bluuebunny/crossref_metadata_2025_split huggingface dataset:
Secondary prevention of patients with ischaemic stroke after recanalization treatment
Authors: Benesová Michaela , Krivošík Marek , Kosírová Stanislava , Foltánová Tatiana 
Published: July 2022

Abstract
We performed a retrospective analysis of 100 patients with ischaemic stroke. All patients underwent intravenous thrombolysis in the acute care setting (avg. 2.8 hours, max 4.5 hours) and 10 of them also underwent mechanical thrombectomy. For 20% of the patients, the stroke was fatal. Door to needle time was 38.46 minutes. Although changes in antithrombotic treatment were introduced due to strokes, there was no significant difference in National Institute of Health Stroke Scale scores between the patients who were on antithrombotic treatment and those who were on no antithrombotic treatment.
Reverse Engineering of Parts with Asymmetrical Properties Using Replacement Materials
Authors: Aladag Mehmet , Bernacka Monika , Joka-Yildiz Magdalena , Grodzki Wojciech , Zamojski Przemysław , Zgłobicka Izabela 
Published: July 2022

Abstract
Reverse engineering (RE) aims at the reproduction of products following a detailed examination of their construction or composition. Nowadays, industrial applications of RE were boosted by combining it with additive manufacturing. Printing of reverse-engineered elements has become an option particularly when spare parts are needed. In this paper, a case study was presented that explains how such an approach can be implemented in the case of products with asymmetric mechanical properties and using replacement materials. In this case study, a reverse engineering application was conducted on a textile machine spare part. To this end, the nearest material was selected to the actual material selection and some mechanical tests were made to validate it. Next, a replacement part was designed by following the asymmetric push-in pull-out characteristic. Finally, the finite element analysis with Additive Manufacturing was combined and validated experimentally.
Key Challenges and Opportunities of Industry 4.0 in Metallurgical Industry in Slovakia
Authors: Richnák Patrik 
Published: July 2022

Abstract
The main objective of the paper was to identify and explain the terms related to Industry 4.0 based on a review of foreign literature and then to interpret the results of the quantitative research. In the construction of the theoretical framework, the analysis, synthesis, comparison of scientific terminology from foreign scientific sources from recent years. Interpretation of the studied issues from the practical aspect was realised on the basis of the evaluation of the questionnaire survey. The object of the research were 29 enterprises participating in the metallurgical industry in Slovakia. The research results indicate that the respondents have partial information about Industry 4.0. Data evaluation also indicated that most of the respondents are applying Industry 4.0 in production. Industry 4.0 in metallurgical enterprises mainly optimise business processes. The use of smart sensors from Industry 4.0 technologies as well as advanced simulation is dominant in metallurgical enterprises in Slovakia.
Exposure to nanographene oxide induces gene expression dysregulation in normal human astrocytes
Authors: Rudnytska Olha V. , Kulish Yuliia V. , Khita Olena O. , Minchenko Dmytro O. , Tsymbal Dariia O. , Viletska Yuliia M. , Sliusar Myroslava Y. , Trufanova Dariia D. , Minchenko Oleksandr H. 
Published: July 2022

Abstract

Objective. Nanographene oxide, an oxidation derivative of graphene, is considered to be one of the nanomaterials attractive for biomedical applications, although this nanomaterial is toxic. The increasing exploitation of graphene-based materials necessitates a comprehensive evaluation of the potential impact of these materials on the human health. Moreover, it is necessary to investigate in detail the mechanisms of its toxic effect on living cells particularly at the genome level. The present study aimed to evaluate the impact of low doses of nanographene oxide on the expression of key regulatory genes in normal human astrocytes.

Methods. Normal human astrocytes, line NHA/TS, were exposed to low doses of nanographene oxide (1 and 4 ng/ml) for 24 h. RNA was extracted from the cells and used for cDNA synthesis. The expression levels of NAMPT, TSPAN13, BCAR3, BRCA1, PTGS2, P4HA1, and P4HA2 mRNAs as well as microRNAs were measured by quantitative polymerase chain reaction.

Results. It was found that the low doses of nanographene oxide induced a dysregulation in the expression of the key regulatory genes in normal human astrocytes in dose-dependent (1 and 4 ng/ml) and gene-specific manner. Nanographene oxide also strongly suppressed the expression of NAMPT, BCAR3, and TSPAN13 genes and significantly up-regulated BRCA1, PTGS2, P4HA1, and P4HA2 ones with a more significant effect in P4HA1 and P4HA2 genes. The expression of miR-96-5p and miR-145-5p was also down-regulated in astrocytes treated with nanographene oxide in a dose-dependent manner.

Conclusion. The data obtained demonstrate that the low doses of nanographene oxide disturbed the genome functions by changing the expression levels of key regulatory genes in gene-specific and dose-dependent manner. Moreover, a higher dose of nanographene oxide induced more pronounced changes in expression of genes indicating for both genotoxic and neurotoxic possible effects in the normal human astrocytes.
The dilemmas of systematic literature review: the context of crowdsourcing in science
Authors: Lenart-Gansiniec Regina 
Published: July 2022

Abstract

Purpose
The proliferation of knowledge in management sciences is accelerating rapidly. The condition of reliability and originality of research underlies all research activities. Therefore, literature review as a research method is more important than ever. However, searching the enormous and still growing number of published studies can be a difficult undertaking, especially for new concepts for which there is no well-established theory and related conceptualisation or operationalisation. Such newness in turn may limit the conduct of any literature review. The aim of the article is to identify, assess, and classify dilemmas that researchers may face during the planning stage of a systematic literature review.

Findings
Based on the literature review and the author's own experience, a list of ten dilemmas was formulated using the example of a systematic literature review in the context of crowdsourcing in science.

Practical implications
Due to the consolidation of publications in the field of systematic literature review methodology, this article focuses on the dilemmas and challenges that may be faced by researchers conducting systematic literature reviews, especially in the context of new and poorly identified issues. We present dilemmas but also ways to solve them. Our article is aimed at researchers, scientists, and PhD students who may need to conduct a systematic literature review.
Extension and Validation of the Self-care Index to Predict Transfer to a Post-acute Care Institution in Internal Medicine Patients / Erweiterung und Validierung des Selbstpflegeindexes bei internistischen Patienten mit dem Ziel eine Verlegung in eine post-akute Nachsorgeinstitution vorauszusagen
Authors: Conca Antoinette , Koch Daniel , Regez Katharina , Kutz Alexander , Haubitz Sebastian , Schuetz Philipp , Mueller Beat , Schindler Christian , Spirig Rebecca , Petry Heidi 
Published: July 2022

Abstract
A systematic screening of patients with a need for post-acute care is a helpful support for interprofessional discharge planning teams. We aimed to test self-care abilities, measured by the self-care index (SPI) as predictors of post-acute care transfer and to update the existing SPI prediction model.
We analysed data from a prospective, observational cohort study conducted at the Kantonsspital Aarau between February and October 2013. We updated the SPI model, adding age and gender using a training and validation data set. Logistic regression models were run on the outcome “transfer to a post-acute care facility” and judged based on their AUC (area under curve), AIC (Akaike information criterion), and BIC (Bayesian information criteria) values. ROC curves (receiver operating characteristic) were derived from the models; and cut-points for the linear predictors of the models were defined (thus defining the new scores). Sensitivities and specificities were calculated.
This study included 1372 adult internal medicine in-patients admitted from home, who either returned home or were transferred to a post-acute care institution. The total SPI score was a significant predictor for post-acute care referral (p < 0.001). Including age and gender in the SPI model increased the AUC to 0.85 (training) and 0.84 (validation). An improvement in the AUC by 3% (0.81 [95% CI: 0.77–0.85] to 0.84 [95% CI: 0.80–0.87]), compared to the original SPI was achieved (p = 0.004). The new score reached a sensitivity of 81% and specificity of 74% compared to a sensitivity of 64% and specificity of 84% for the original score.
The extended SPI can be used as a tool for individualised discharge organisation of internal medicine patients with higher accuracy.
First Fifty Cases with En-Bloc Holmium Laser Enucleation of the Prostate
Authors: Georgiev Georgi S. , Kolev Nikolay H. , Dunev Vladislav R. , Atanasov Boyan S. 
Published: July 2022

Summary
In the last decade, the Holmium Laser Enucleation of the Prostate (HoLEP) has become the new gold standard for surgical treatment of benign prostatic hyperplasia (BPH). This treatment has several modifications, and the latest one is en bloc (single piece) enucleation. This new method reduces the operative time and risk of early incontinence. The long-term effect is much better than transurethral resection of the prostate (TURP). We applied an effective method for treating benign prostatic hyperplasia with maximum safety, minimal hospital stays, short operative time, and minimal complications. We operated on 50 patients with BPH with a prostate volume between 30-120 cc. Transrectal ultrasound, uroflowmetry, PSA test, IPSS (International Prostate Symptom Score), residual urine, digital rectal examination, and laboratory blood and urine tests were performed preoperatively. We used Holmium laser (Auriga XL) 50 W, 600 μm fiber and morcellator (Richard Wolf PIRANHA). During the procedure, the laser’s operating power was 36 W. En bloc Holmium enucleation was performed in all patients, followed by morcellation of the prostatic tissue. The time for enucleation was 11-52 min, morcellation time - 1-10 min, the weight of the enucleated tissue - 15-100 g, enucleation efficiency - 0.67-3.03 g/min, postoperative catheterization time - 24-72h, and hospital stay was 1 to 3 days. One blood transfusion was required. There were no patients with postoperative incontinence or other complications. We conclude that еn bloc Holmium enucleation in BPH is an effective method of treatment that offers maximum performance combined with short operative time, shorter hospital stays, and minimal risk of complications. The learning curve requires at least twenty cases. The recommended prostate gland size for the initial trial should be between 50-60 cc. Starting with small-sized glands increases the risk of capsule perforation, and the enucleation plane is more difficult to find.
A Retrospective Analysis of Treatment of Covid-19 with Favipiravir
Authors: Kulzhanova Sholpan A. , Konkayeva Maiya E. , Smagulova Zauresh K. , Beisenbieva Nazira N. , Tuleshova Gulnara T. , Utegenova Aigul M. , Turebaeva Gulsimzhan O. , Nurakhmetova Gaukhar A. 
Published: July 2022

Summary
One of the potential therapeutic agents for treating COVID-19 is favipiravir (FPV). This retrospective study compared the treatment of COVID-19 with (FVP group) or without (control group) favipiravir. Demographic characteristics and initial clinical indicators in the two groups were comparable. The level of oxygen saturation, respiratory rate, and prevalence of chest pain in the FVP group returned to normal significantly earlier (on the seventh day) compared to the control group (p<0.05). Improvement of patients’ condition in the FVP group occurred significantly earlier than in the control group (p <0.001). In conclusion, FVP treatment’s efficacy was higher than the control management strategy and established an individualized set of therapeutic agents. However, more detailed studies are needed to evaluate the efficacy of COVID-19 treatment with favipiravir fully.
Successes and obstacles in the work of upper-secondary schools with newly arrived students: A constructivist-inspired analysis of teachers’ verbal accounts regarding their schools’ organizational and practical work
Authors: Medegård Emma , Henrixon Karolina , Basic Goran 
Published: July 2022

Abstract
This study presents new knowledge arising from teachers’ verbal accounts of successes and obstacles in the organizational and practical work of upper-secondary schools with newly arrived students. The analysis reveals several dimensions contributing to the construction and reconstruction of successes and obstacles in the teachers’ accounts. Teachers are constructed as actors with a power advantage relative to the “newly arrived student.” They set the agenda for student behavior, with an inclusive approach that is crucial to achieving success and counteracting obstacles. The approach imposes demands on how upper-secondary schools organize their work with newly arrived students and plays a role in determining supports and room for maneuvering that teachers have. Through the presented analysis, the study contributes to the development of knowledge in terms of four areas. First is the narrative processing of the combination of success and obstacles in the work with newly arrived students. Second is the importance of these stories for the representation of social pedagogical recognition and lack of recognition in the school context. The third area is identity creation and re-creation of professional actors (teachers), and the fourth area of knowledge involves alternative approaches to analysis compared to the typically expected didactic perspective. The study also contributes to the development of knowledge regarding the question of how a school’s morals function in relation to the previous and current experiences of teachers and newly arrived students.
Movement belongs to all of us? Thinking interdisciplinarity with early childhood studies and kinesiology
Authors: Land Nicole 
Published: July 2022

Abstract
This article takes up a question of how early childhood studies and kinesiology might undertake interdisciplinarity together. Working with the provocation of the phrase ‘movement belongs to all of us’, this article probes the character of three particular interdisciplinary alliances between early childhood studies and kinesiology, asking what becomes possible and impossible for interdisciplinary work amid each collision. These intersections include moving with humans and new materialist movements, dancing childhoods and bodily boundaries, and doing collaboratories and social justice. Working closely with each of these intersections, I propose discord, perceptibility, and collectivity as three possible practices toward inventing unfamiliar interdisciplinarity between early childhood studies and kinesiology.
School, forced displacement and teacher knowledge in Bogota, Colombia
Authors: Rodríguez Ana María León , Becerra Absalón Jiménez 
Published: July 2022

Abstract
This article presents an analysis of the links between teacher practice and forced displacement based on a theoretical conceptualization and the narratives of the main actors: teachers and students of the first cycle of two schools in the city of Bogota. We analyze the contexts of the schools and the dynamics of the school scenarios. The research enabled us to identify the territories’ importance in the construction of identities and people’s life histories; to reaffirm the school as a political and social ground; the teacher´s role in mediating and encouraging new experiences and life projects, and finally the importance to generate qualification processes with and for the teachers who enhance their practices with forced displaced children in a “welcoming” community.
Qualities Required for Accounting Professionals from the Perspective of Capitalizing the Accounting Information
Authors: Ciuhureanu Alina-Teodora 
Published: July 2022

Abstract
Often, the relationship between professional accountant and manager works on the principle “I offer you if you ask” but, in our opinion, a good professional is the one who knows how to emphasize the need to “request”. Thus, in order to have this capacity, professional training is not enough but it requires many other qualities of the accounting team, namely the ability to perceive and act very quickly, adaptability, creativity (not in a negative sense), teamwork, ability to learn etc. In this context, the paper aims to analyze the perception of managers regarding the qualities needed by professional accountants from the perspective of capitalizing the accounting information.
Fundamentals of Financial Operations in the Military Organisation
Authors: Milandru Marius , Floştoiu Sebastian 
Published: July 2022

Abstract
Public financial resources are constituted at the level of the state budget and are used and allocated to institutions for the general interests of the community in accordance with national legislation. Their optimal use requires the application of appropriate financial management, which in concrete terms is the science and art of conducting operations for the full use of financial resources to efficiently achieve the proposed objectives. Thus, financial management starts with the organization of financial planning, through forecasting, and is completed by the execution of the allocated budget. The coordination of public financial resources leads to the achievement of financial discipline, as well as to the obligation to respect the legality and conformity of public expenditure regulations applicable to the military organisation.
The Impact of Public Budget Distortion on the Defence Capabilities of the New European Nato Member States
Authors: Müllner Vojtěch , Nečas Kamil 
Published: July 2022

Abstract
Armies’ capabilities are determined by their endowments of resources. The economic crisis that began in 2008 has distorted public budgets, which forced states to start cost-cutting policies. If we focus on the policy of new NATO member states, we can observe that public expenditure cuts affect defense budgets in different states in various ways. If we compare the defense capabilities of countries at the beginning of the economic crisis and ten years after the outbreak of the crisis, the reduction in defense spending is reflected in the loss of some defense capabilities due to the limited possibilities of maintaining and modernizing existing military equipment. Countries that have reduced their defense spending over the long term show a more significant loss of defense capability than countries that reduced their defense spending only in the period immediately after the economic crisis. The different approach to defense spending confirms the previously described phenomenon of free-riding by some NATO member states, which rely on the defense capabilities of their alliance partners while they are slowly losing their defense capabilities.
Effects of Globalization on the Internationalization and Management of the Activity of the Multinational Companies
Authors: Stanciu Leontin , Stanciu Cristian-Lucian 
Published: July 2022

Abstract
Under the conditions of the contemporary economy, the intensification of foreign trade is a fundamental requirement of economic growth, of business internationalization and, implicitly, of economic globalization. On the other hand, business development in the international environment, regardless of the size of the economic entities or their field of activity, tends to become a prerequisite of organizational existence. For this reason, the business strategies must be synchronized with the requirements and demands of the economic globalization. In this context, the authors of the present paper aimed to identify and briefly present the main effects of the globalization on the business internationalization and the management of the multinational companies.
Economic Imbalances Caused By the Abuse of Some Clauses Inserted in Credit Contracts
Authors: Țîrlea Mariana Rodica 
Published: July 2022

Abstract
Credit agreements are membership contracts. Sometimes, within these types of contracts, significant imbalances can occur caused by the insertion of abusive clauses in the credit agreements. Significant imbalances are of an economic nature, created in order for professionals to obtain economic benefits in a manner that is contrary to good faith. The finding of abusive clauses is made “in concrete” only by the court. Once these abusive clauses have been found by the court, the abusive clauses can follow two variants of solutions, respectively: a). Within the contract they may be replaced by other clauses and b). they can be completely removed from bank credit agreements. In the first variant, the abusive clauses will be replaced with other clauses that will have as objective, the correction of the significant imbalances and the assurance of the balance of the credit agreements. In the second variant, the abusive clauses are struck by nullity and can sometimes have major consequences, materialized even in the cancellation of the entire credit agreement. The adopted solution will be based on the concrete situation of each case. The practice further proves the existence of these abusive clauses in one form or another, in credit agreements.
International Ideation for Hybrid ESP Teaching
Authors: Georgieva Valentina 
Published: July 2022

Abstract
The paper shares some of the experience gained in the ideation process of generating and designing tasks in Specialised Military English for a hybrid learning environment. The product of the ideation is targeted at military and security specialists and is the result of an international project under the EU’s Erasmus+ programme N 2020-1-BG01-KA203-079117. Definitions of ideation, interactive activity/learning, hybrid learning, and ESP are suggested. The main phases of the HELPSec international ideation process of the project partners are presented and some techniques of this process are exemplified.