bluuebunny/crossref_metadata_2025_split huggingface dataset:
Matriks Circulant Kompleks Bentuk Khusus 3 × 3 Berpangkat Bilangan Bulat
Authors: Mamula Dewinta , Achmad Novianita , Resmawan Resmawan 
Published: January 2022

This article identifies the general form of matrix power and trace of an integer power of Special Form of the 3 × 3 Complex Circulant matrix. The research begins to determine the general form of an integer power of Special Form of the 3 × 3 Complex Circulant matrix, followed by determining the general form trace of an integer power of Special Form of the 3 × 3 Complex Circulant matrix. The proof is done by using mathematical induction. The final result of this article is to obtain the general form of the matrix A^n and tr(A^n) for n integers in special form of the 3 × 3 complex Circulant matrix.
The canonical FGF-FGFR signaling system at the molecular level
Authors: Szybowska Patrycja , Haugsten Ellen Margrethe , Wiedlocha Antoni 
Published: January 2022

Abstract
Extracellular signaling molecules, among them the fibroblast growth factors (FGFs), enable cells to communicate with neighboring cells. Such signaling molecules that receive and transmit a signal require specific tyrosine kinase receptors located at the cell surface (fibroblast growth factor receptors, FGFRs). The binding of a signaling molecule to its specific receptor results in receptor dimerization and conformational changes in the cytoplasmic part of the receptor. The conformational changes lead to trans-autophosphorylation of the tyrosine kinase domains of the receptors and subsequently to induction of several downstream signaling pathways and expression of appropriate genes. The signaling pathways activated by FGFs control and coordinate cell behaviors such as cell division, migration, differentiation, and cell death. FGFs and their transmembrane receptors are widely distributed in different tissues and participate in fundamental processes during embryonic, fetal, and adult human life. The human FGF/FGFR family comprises 22 ligands and 4 high affinity receptors. In addition, FGFs bind to low affinity receptors, heparan sulfate proteoglycans at the cell surface. The availability of appropriate ligand/receptor pair, combined with the co-receptor, initiates signaling. Inappropriate FGF/FGFR signaling can cause skeletal disorders, primarily dwarfism, craniofacial malformation syndromes, mood disorders, metabolic disorders, and Kallman syndrome. In addition, aberrations in FGF/FGFR signaling have already been reported in several types of malignant diseases. Knowledge about the molecular mechanisms of FGF/FGFR activation and signaling is necessary to understand the basis of these diseases.
Comparative Toxicity of Lunar, Martian Dust Simulants, and Urban Dust in Human Skin Fibroblast Cells
Authors: Wise James T.F. , Xie Hong , Wise John Pierce , Mason Michael , Jeevarajan Antony , Wallace William , Wise John Pierce 
Published: January 2022

ABSTRACT
The National Aeronautics and Space Administration (NASA) has plans to further their manned space exploration to Mars and possibly beyond. The potential toxicity of lunar and Martian dusts to astronauts is a big concern. Primary routes of exposure for astronauts are dermal contact, ocular contact, and inhalation. In this study, we focused on dermal contact exposure using human skin cells to investigate the cytotoxic and genotoxic effects of two fractions of lunar dust simulant (JSC-1A-vf, JSC-1A-f) and a Mars dust simulant (Mars-1A), and compared them to urban dust (urban particulate matter), as urban dust toxicity is better understood and thus, provides a good comparison. Our data show the three simulants and urban dust are cytotoxic to human skin cells. The JSC-1A-vf lunar dust simulant is more cytotoxic than the JSC-1A-f and urban dust. Urban dust cytotoxicity is similar to Mars dust simulant after 120 h exposure. All three dust simulants and urban dust show similar low genotoxicity effects. Our data suggest extraterrestrial dust can damage skin cells and may have the potential to be harmful to humans.
Mapping by VESGEN of Wing Vein Phenotype in Drosophila for Quantifying Adaptations to Space Environments
Authors: Parsons-Wingerter Patricia , Hosamani Ravikumar , Vickerman Mary B. , Bhattacharya Sharmila 
Published: January 2022

ABSTRACT
Vascular patterning is a key, genetically responsive phylogenetic classifier of tissues in major organisms flown in space, such as the wings of Drosophila melanogaster (the fruit fly), mouse retina, and leaves of Arabidopsis thaliana. Phenotypes of increasingly abnormal ectopic wing venation in the highly stereotyped Drosophila wing generated by overexpressing the H-C2 construct of Notch antagonist Hairless (Johannes and Preiss, 2002) were mapped and quantified by NASA’s VESsel GENeration Analysis (VESGEN) software. By several confirming vascular parameters, the eight stereotyped wing veins remained quite constant in wild type compared to Class 5 H-C2, the most perturbed category of the H-C2 overexpression phenotypes. However, ectopic veins increased in number from 1 in the wild type, to 18 in Class 5 H-C2. We therefore demonstrate the feasibility of using VESGEN to quantify microscopic images of altered wing venation in Drosophila melanogaster. We further determined that several of the signal transduction pathways affecting wing vein patterning were altered by spaceflight, according to gene expression differences observed in our transcriptomic data from a previous shuttle flight experiment. Future studies will help characterize the extent to which these gene expression changes can cause even subtle developmental changes using model organisms, such as Drosophila. Therefore, we propose that the sensitive analyses provided by VESGEN software will not only serve as a useful tool to map the genetics of wing vein patterning for terrestrial applications, but also for future phenotypic studies with Drosophila for spaceflight missions.
ANASIR BABAD DESA SIRKANDI DALAM PERSFEKTIF STRUKTURALISME LEVI-STRAUSS
Authors: Kurnianto Ery Agus 
Published: January 2022

The Babad Desa Sirkandi is one of the folklore that lives and develops in the social community of the Banjarnegara community. Babad Desa Sirkandi is an interesting topic of this study because as far as the author's knowledge there has been no research that examines the chronicle (Babad). Babad Desa Sirkandi is a baboon of folklore in the village of Sirkandi. To analyze the chronicle, researcher used descriptive methods. The approach used to analyze the Babad Sirkandi is an objective approach. This approach was carried out to analyze the intrinsic elements that built the Babad Desa Sirkandi story. the object this research is folklore from Banjarnegara in the form of babad, namely Babad Desa Sirkandi. Based on the research result, it can be concluded that (1) Babad Desa Sirkandi consists of eight episodes.; (2) the babad is formed by 56 mythems: (3) the identified myths have five binary opposition structures; (4) Babad Desa Sirkandi has three historical life structures: (5) Babad Desa Sirkandi has three layers of social strata, namely the upper layer, middle layer, and lower layer; (6) Karanggintung Village community believes in the concept of Manunggaling Kawula Gusti: (7) there are three symbolic messages.
NILAI-NILAI MULTIKULTUR DALAM ANTOLOGI CERITA RAKYAT SINGKAWANG
Authors: Febrianti Binar Kurniasari 
Published: January 2022

This paper aims to describe multicultural values in Singkawang folklore. Singkawang folklore anthology, which reveal past socio-cultural life inherited from generation to another generation, underlies the paper. Folklore tells things related to natural phenomena, the social life of the community, and customs of origin. This paper is descriptive analysis with a literature study method and uses the theory of sociology of literature. The data source of this paper is Singkawang folklore text by applying the technique of reading and writing. The results showed that Singkawang folklore contained multicultural values, including tolerance values, equality values, religious values, cultural values, solidarity values, trade values, family values, simplicity, unyielding values, values of appreciation, and values of keeping promises. These multicultural values are still relevant and applied today. Thus, Singkawang folklore shows cultural diversity that is important as a socio-cultural reality.
LANSKAP LINGUISTIK PADA RUMAH SAKIT DI KABUPATEN KULON PROGO
Authors: Riani NFN 
Published: January 2022

Penelitian ini membahas pemakaian bahasa di lingkungan rumah sakit dalam perspektif linguistik lanskap. Papan nama dan petunjuk di rumah sakit memiliki peranan penting dalam memberikan informasi kepada para praktisi kesehatan dan terutama pasien yang berobat. Oleh sebab itu, penelitian ini bertujuan untuk mendeskripsikan pengunaan bahasa Indonesia pada ruang publik di lingkungan rumah sakit dari aspek situasi kebahasaan, bentuk bahasa, kesalahan dalam pemakaian bahasa, dan fungsinya. Penelitian ini merupakan penelitian deskriptif kualitatif. Data penelitian ini adalah teks bahasa Indonesia atau Inggris pada rumah sakit di Kabupaten Kulon Progo, DIY. Metode penelitian meliputi mengobservasi, mendokumentasikan data dengan cara difoto, mengklasifiasikan data, menganalisis data. Hasil penelitian menunjukkan bahwa berdasarkan aspek situasi, penggunaan bahasa di rumas sakit terdiri atas (1) monolingual (bahasa Indonesia atau bahasa Inggris) dan (2) bilingual (bahasa Indonesia dan bahasa Inggris). Berdasarkan bentuknya terdapat lima jenis, yaitu (1) kata, (2) frase, (3) kalimat, dan (4) wacana. Berdasarkan penggunaan bahasa diketahui terdapat kesalahan pada aspek (1) ejaan, (2) diksi, (3) kalimat, dan (4) wacana. Berdasarkan fungsinya ada tiga jenis, yaitu (1) informasi, (2) imbauan, (3) petunjuk, dan (4) ungkapan fatis.
Sistem Traksi Kereta Rel Listrik Dengan Teknologi VVVF
Authors: Taufik Hidayat  
Published: January 2022

The electrical system of electric railcar with the variable voltage variable frequency (VVVE) technology has been equipped with different devices functioning to change the DC-link voltage from the overhead line in undesired conditions. It also transmits energy powered by the motor due to a braking process not able to be transmitted back to the overhead line, and keeps the DC-link voltage stable during the braking process. The inverter functions to change the DC-link voltage into a source of AC 3 phase whose voltage and frequency can be regulated. The voltage and frequency variables produced are used to power four induction motors. The rotation speed of the motor can be set as desired by regulating the voltage and frequency of the AC source. Another function is to transmit back the force generated by the motor during the braking to the overhead line.
Perancangan Alat Bantu Proses Penyortiran Alumina Ball Pada Mesin Ball Mill Departemen Body Preparation
Authors: Cucu Wahyudin  , Ikhsan Maulana  
Published: January 2022

XYZ adalah perusahaan yang bergerak dalam bidang manufaktur yangmemproduksi keramik.

Penelitian ini dilakukan di departemen body preparation, tempat terjadinya proses penyortiran alumina bal
Alumina ball adalah sebuah batuan yang digunakan untuk proses penggilingan bahan baku utama di mesin ball mill.
Hasil pengamatan di lantai produksi, menunjukan bahwa kegiatan penyortiran alumina ball masih dilakukan secara manual dan merupakan kegiatan yang rutin. Proses penyortiran alumina ball yang umumnya berlangsung lamban menyebabkan berbagai keluhan operator, seperti timbulnya rasa pegal-pegal dan nyeri atau sakit pada bagian punggung, kaki, leher, dan kaki. Kegiatan penyortiran secara manual menghasilkan 2 ton alumina ball tersortir per hari, hanya 26 dari yang seharusnya disortir, dengan melibatkan empat orang operator.
Oleh karenanya, perbaikan sistem kerja perlu segera dilakukan, diantaranya dengan merancang alat saringan yang dapat mempermudah, mempercepat dan memperbaiki posisi kerja operator sehingga selama bekerja memiliki rasa rasa nyaman dengan hasil sortiran yang lebih banyak.
Proses perancangan alat saringan pada penelitian ini menggunakan metode Ouality Function Deplovment (OFD) yang dikombinasikan dengan pendekatan engineering design yang banyak digunakan pada proses perancangan mesin.
Pengaruh Waktu Penahanan Proses Pengerasan Permukaan Cyaniding Terhadap Laju Difusi Nitrogen Terhadap Struktur Dan Sifat Mekanik Baja Perkakas Assab Xw-42
Authors: Abrianto Akuan  
Published: January 2022

Salah satu metoda pengerasan permukaan dengan jalan merubah komposisi kimia yaitu dengan proses Cyaniding. Atom N (Nitrogen) diperoleh dari hasil reaksi garam KFe(CN), dengan oksigen/udara dengan aktivator Na2CO3. Atom N akan berdifusi masuk kedalam permukaan sehingga pada permukaan akan diperoleh lapisan white keras Fe4N dan Fe2N yang sifatnya keras. Proses cyaniding ini dilakukan dengan memyvariasikan waktu yaitu 3, 9 dan 21 jam dengan temperatur 580oC. Dari hasil penelitian ini lapisan yang terbentuk pada proses 3 jam yaitu dengan rata rata 40,870Âµm , untuk proses 9 jam lapisan yang terbentuk rata-rata 58Âµm dan proses 21 jam lapisan yang terbentuk rata-rata 61,109Âµm. Sedangkan kekerasan yang dihasilkan akibat terbentuknya lapisan nitrida besi: Fe4N adalah untuk proses 3 jam 771,61 Hv, proses 9 jam 763,13Hv dan 21 jam 760,27 Hv.
PENERAPAN KOMUNIKASI RISIKO BENCANA PADA THE CANGKRINGAN JOGJA VILLAS & SPA
Authors: Negoro Sherly Hindra 
Published: January 2022

Natural disaster are one the form of crisis that comes from external organization. Natural disaster are unpredictable. For organization, risk communication is important as part of prevention or need anticipation effort. This research discusses risk communication in the context of disaster that implemented by hotels located in high risk disaster area especially Merapi eruption. Disaster areas can be a tourist attraction. On the other hand, the natural disaster can also decrease the number of tourist visit. This research is a qualitative research with case study method. The results showed that The Cangkringan Jogja Villas Spa carries out risk identification and analysis to prevent a bad situation for the public. Risk analysis is carried out with knowledge approach and cultural approach. The Cangkringan Jogja Villas Spa involves internal and external parties to communicate risk. In order to anticipate ambiguous information, The Cangkringan Jogja Villas Spa formed an Emergency Response Unit. They are responsible for carrying out the functions and roles based on Standard Operating Procedure (SOP).
Migraine Headache: A Bangladesh Perspective
Authors: Ahmed Kazi Gias Uddin , Mahmud Reaz , Islam Md Rafiqul , Chowdhury Ahmed Hossain , Alam Iftekher , Aftab Rassel Mohammad , Monayem Farhana Binte 
Published: January 2022

Background: Migraine headache is one of the commonest cause of primary headache. This study aims to reveal the clinical profile of migraine headache in Bangladeshi people presented in Headache clinic, Dhaka Medical College Hospital. It will give an overview on presentation of migraine and its functional consequences among the people of Bangladesh.
Methods: The study was a hospital based cross sectional observational study. It was conducted in the Headache clinic Dhaka Medical college Hospital from January 2018 to December 2018. About 854 patients with headache was attended in the headache clinic during the study period. Of that 234 patients were diagnosed as migraine according to ICHD-3 classification and 75 patents were enrolled in this study by systematic sampling. Details were collected using a preformed questioner.
Results: In this study migraine burden among the headache patients found to be about 25%.The mean age of the onset of the migraine headache in this study was found to be 25.2±11.86 years, in most of the cases (4 68%) in 15-34 years age group. In this study 36% of the patient with migraine had positive family history which is significantly higher in patients with migraine with aura (52% vs. 30% p value <0.5). In this study about 81% of the patient has single or multiple trigger factors. Along with other known factor sun exposure and journey was found to be the important trigger factors for Bangladeshi population. In this study 22% of the female migraineurs and 33% of male migraineurs had aura. About 53% of the patient with aura had combinations of aura and 47% patient had exclusive visual aura. In the present study 100% of the patient had visual aura, 42% had brainstem aura and 10% had sensory aura. The study revealed that 25% patient had chronic daily headache due to migraine, 26% patient had >5 attack/ month and 15% patient had < 4 attack per month. In this study 44% had moderate headache and 56% had severe headache according to VAS score. Chronic migraine with anxiety, chronic migraine with medication overuse Migralepsy, Status migrainosus were found as a complications of migraine in this study. According to MIDAS score Patient largely had Mild (32%) to Moderate (34.67%) disability.
Conclusions: Clinical profile of migraine in Bangladesh differs in some trigger points and migraine subtypes than the western world. Sun exposure and journey found to be most important triggers. Migraine with brainstem aura occurs in a significant number of the patient.
Bangladesh Journal of Neuroscience 2019; Vol. 35 (1): 1-9
Risk Factors Analysis in Various Subtypes of Ischemic Stroke According to TOAST Criteria in a Tertiary Care Hospital
Authors: Mohammad Rakib Hasan , Islam Md Rafiqul , Md Shahidullah - , Rahman Hasan Zahidur , Hossain Refayet Chowdhury Neamul , Rashid Mohammad Bazlur 
Published: January 2022

Background: Stroke is the third leading cause of death in adult population throughout the world and is the most common cause of severe adult physical disability. The aim of the study is to identify the major risk factors in various subtypes of ischemic stroke according to TOAST criteria. Methods: A Cross-sectional observational study was conducted from January, 2018 to December 2018 in the department of Neurology, Bangabandhu Sheikh Mujib Medical University, Dhaka. All the patients of first ever ischemic stroke within 14 days diagnosed by history, clinical examination and neuroimaging (CT scan of head / MRI of brain), meeting the inclusion and exclusion criteria were included in the study. Results: Present study showed that among the 52 ischemic stroke patients mean age of the respondents was 57 ± 12.37 years with a slightly higher male predominance. Male to female ratio was 1.2:1. Dyslipidemia 44 (84.6 %) and hypertension 37 (71.2 %) were the most common risk factors, followed by obesity and overweight 33(63.5%), smoking 32 (61.5%), diabetes mellitus 29 (55.8%), family history of vascular event 27(51.9 %) and past history of vascular event 14 (26.9%). TOAST Subtype distribution of study population was large-artery atherosclerosis 18 (34.6%) followed by cardioembolism 11(21.2%), small-vessel occlusion 10(19.2%), stroke of other determined etiology 3(5.8%), and stroke of undetermined etiology 10(19.2 %) of patients. In cardioembolic subtype significant association was found with ischemic heart disease (P=0.001) and chronic rheumatic heart disease (P= <0.001). Conclusion: In this study large-artery atherosclerosis was the most common subtype, followed by cardioembolism, small vessel occlusion, stroke of undetermined etiology and stroke of other determined etiology subtypes. Dyslipidemia was found to be the most common risk factor, others were HTN, diabetes and smoking. Ischemic heart disease and rheumatic heart disease were very important cause and comorbidities of cardioembolic types of ischemic stroke.
Bangladesh Journal of Neuroscience 2019; Vol. 35 (1): 14-21
Socio Demographic and Headache Characteristics of Migraine Patients in a Tertiary Care Hospital in Bangladesh
Authors: Bhattacharjee Manabendra , Karim MD Rezaul , Hossain Akmal , Mondol Gurudas , Biswas Rajib 
Published: January 2022

Migraine is a common type of headache. After tension type headache, it is the second common cause of primary headache disorder with a female preponderance.This cross sectional study was done toassess the sociodemographic characteristics of migraine patients in Bangladeshi population and to see the characteristics of headache and associated comorbidities of migraine patients.The study was conducted in a tertiary care hospital (Mymensingh medical college) of Bangladesh.The study subjects consisted of 60 patients with migraine headache seen in neurology OPD.Mean age was 32.03± 11.74 yrs. Male female ratio was 1: 2.7.Most of them are housewives (61.6%). 22% had family history of headache. Most of the patients had severe (53.4%) and frequent (e”3 per month) headache attacks. Aura was present in 25% patients. Depressive illness was the associated comorbid condition which was found in 15% patients.
Bangladesh Journal of Neuroscience 2019; Vol. 35 (1): 22-26
Progressive Limb Weakness in A Young Man: A Case Report of POEMS Syndrome
Authors: Chowdhury Ashish , Saha Sujan , Al Muzahid Md Abdullah , Roy Uttam , Kabir Md Suman , Agarwalla Ajay Kumar , Reza Samim , Sarker Imran , Islam Md Rafiqul 
Published: January 2022

Polyneuropathy is an initial presentation and essential feature of POEMS ( polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome. Neuropathy is typically distal, symmetric and slowly progressive with demyelinating changes. After a gradual proximal spread, it usually results in severe muscle weakness and functional disabilities. In the present report, we describe a 40-year-old diabetic male presented with gradually progressive weakness of both lower limbs for 1 year followed by the involvement of both upper limbs for the last 3 months. On examination hyperpigmentation, lymphadenopathy, gynecomastia, anasarca, hepatomegaly, bilateral optic disc swelling, sensory-motor polyneuropathy was found. Laboratory findings showed IgG lambda monoclonal gammopathy, raised VEGF, sensory-motor demyelinating and axonal polyneuropathy. All findings were consistent with POEMS syndrome. The patient was treated with lenalidomide and dexamethasone cyclical therapy with some clinical improvement.
Bangladesh Journal of Neuroscience 2019; Vol. 35 (1): 51-56
Understanding Hemifacial spasm: A Review Of An Uncommon Movement Disorder
Authors: Anwar Nayeem , Nahar Shamsun , Anwar Nawreen Binte , Ullah AKM Anwar 
Published: January 2022

Hemifacial Spasm is a rare condition and often misdiagnosed even by neurologists. Although etiology, pathophysiology is clear, treatment is unsuccessful in many cases. In this review article we focus on etiology, pathophysiology, diagnosis and management of this infrequent movement disorder.
Bangladesh Journal of Neuroscience 2019; Vol. 35 (2): 104-109