bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facebook management as a tool for client communication and research recruitment in a companion animal university veterinary teaching and research hospital setting
Authors: Müller Anna Vilhelmina , Müller Mark Mikael 
Published: January 2022

AbstractBackgroundThere is little peer‐reviewed information about the strategic use of Facebook in companion animal veterinary settings, including for research recruitment. This study evaluates the implementation and execution of a Facebook strategy in a University Teaching and Research Hospital setting and the use of Facebook as a veterinary communication and recruitment tool.MethodsAll posts published on the hospital's Facebook page, messages sent via Messenger, and Facebook insight data from April 2017 to November 2019 (31 months) were reviewed and categorized. Facebook as a recruitment tool was evaluated through a survey among the faculty.ResultsA total of 113 posts were published, the Facebook page had 3485 followers and altogether 590,877 users were reached. The use of a Facebook strategy supported consistent management of the Facebook page. The content was well aligned with the strategy. The survey showed that the faculty experienced a facilitation effect by their recruitment posts, although the actual recruitment varied and ranged from none to the vast majority of all recruited subjects.ConclusionsThis case‐based, descriptive study gives insight and generates awareness about the possibilities and limitations of communication and research recruitment via Facebook. Further research is needed to evaluate if the findings can be generalized.
Molecular detection of parapoxvirus in Ixodidae ticks collected from cattle in Corsica, France
Authors: Cicculli Vincent , Ayhan Nazli , Luciani Léa , Pezzi Laura , Maitre Apolline , Decarreaux Dorine , de Lamballerie Xavier , Paoli Jean‐Christophe , Vial Laurence , Charrel Remi , Falchi Alessandra 
Published: January 2022

AbstractBackgroundSeveral viruses belonging to the family Poxviridae can cause infections in humans and animals. In Corsica, livestock farming (sheep, goats, pigs, and cattle) is mainly mixed, leading to important interactions between livestock, wildlife, and human populations. This could facilitate the circulation of zoonotic diseases, and makes Corsica a good example for studies of tick‐borne diseases.ObjectivesTo gain understanding on the circulation of poxviruses in Corsica, we investigated their presence in tick species collected from cattle, sheep, horses, and wild boar, and characterized them through molecular techniques.MethodsTicks were tested using specific primers targeting conserved regions of sequences corresponding to two genera: parapoxvirus and orthopoxvirus.ResultsA total of 3555 ticks were collected from 1549 different animals (687 cattle, 538 horses, 106 sheep, and 218 wild boars). They were tested for the presence of parapoxvirus DNA on one hand and orthopoxvirus DNA on the other hand using Pangeneric real‐time TaqMan assays. Orthopoxvirus DNA was detected in none of the 3555 ticks. Parapoxvirus DNA was detected in 6.6% (36/544) of ticks collected from 23 cows from 20 farms. The remaining 3011 ticks collected from horses, wild boars, and sheep were negative. The infection rate in cow ticks was 8.0% (12/148) in 2018 and 6.0% (24/396) in 2019 (p = 0.57). Parapoxvirus DNA was detected in 8.5% (5/59) of Hyalomma scupense pools, 8.2% (15/183) of Hyalomma marginatum pools, and 6.7% (16/240) of Rhipicephalus bursa pools (p = 0.73). We successfully amplified and sequenced 19.4% (7/36) of the positive samples which all corresponded to pseudocowpox virus.ConclusionsObviously, further studies are needed to investigate the zoonotic potential of pseudocowpox virus and its importance for animals and public health.
Genotypic and allelic frequency of a mutation in the NHEJ1 gene associated with collie eye anomaly in dogs in Italy
Authors: Marelli Stefano P. , Rizzi Rita , Paganelli Alessandra , Bagardi Mara , Minozzi Giulietta , Brambilla Paola G. , Polli Michele 
Published: January 2022

AbstractBackgroundA 7.8‐kb deletion in intron 4 of the NHEJ1 canine gene is associated with Collie Eye Anomaly (CEA). This deletion has been described in sheep‐herding breeds related to the collie lineage and in several other dog breeds. A genetic test based on this association can distinguish three genotypes: normal, carrier and affected. The present study is a retrospective investigation of the presence of the CEA allele frequencies in selected breeds from the Italian dog population over a 10‐year time span.MethodsGenotype data, for the 7.8 kb deletion in intron 4 of the NHEJ1 gene, from 496 dogs belonging to Border collie (BC, n = 334), Shetland Sheepdog (SS, n = 74), Australian Shepherd (AS, n = 52), Nova Scotia Duck Tolling Retriever (NS, n = 20) and Rough Collie (RC, n = 16) were analysed. The genetic frequency of CEA allele was estimated in breeds with higher observations (BC, SS and AS).ResultsHealthy carriers were 50%, 45%, 29.6%, 17.3% and 12.5% in SS, NS, BC, AS and RC, respectively. The affected recessive homozygotes were 81.3%, 10.8% and 1.5% in RC, SS and BC, respectively. The CEA allelic frequencies were 0.36, 0.16 and 0.087 in SS, BC and AS, respectively.ConclusionThe results support the usefulness of this type of genetic analysis to optimize the care of dogs where the CEA mutation is present, including assessing the health risk to susceptible dogs within a breed and to provide an objective basis for breeding programmes.
Copulas for hydroclimatic analysis: A practice‐oriented overview
Authors: Tootoonchi Faranak , Sadegh Mojtaba , Haerter Jan Olaf , Räty Olle , Grabs Thomas , Teutschbein Claudia 
Published: January 2022

AbstractA warming climate is associated with increasing hydroclimatic extremes, which are often interconnected through complex processes, prompting their concurrence and/or succession, and causing compound extreme events. It is critical to analyze the risks of compound events, given their disproportionately high adverse impacts. To account for the variability in two or more hydroclimatic variables (e.g., temperature and precipitation) and their dependence, a rising number of publications focuses on multivariate analysis, among which the notion of copula‐based probability distribution has attracted tremendous interest. Copula is a mathematical function that expresses the joint cumulative probability distribution of multiple variables. Our focus is to re‐emphasize the fundamental requirements and limitations of applying copulas. Confusion about these requirements may lead to misconceptions and pitfalls, which can potentially compromise the robustness of risk analyses for environmental processes and natural hazards. We conducted a systematic literature review of copulas, as a prominent tool in the arsenal of multivariate methods used for compound event analysis, and underpinned them with a hydroclimatic case study in Sweden to illustrate a practical approach to copula‐based modeling. Here, we (1) provide end‐users with a didactic overview of necessary requirements, statistical assumptions and consequential limitations of copulas, (2) synthesize common perceptions and practices, and (3) offer a user‐friendly decision support framework to employ copulas, thereby support researchers and practitioners in addressing hydroclimatic hazards, hence demystify what can be an area of confusion.This article is categorized under:
Science of Water > Hydrological Processes
Science of Water > Methods
Nanomedicine, a valuable tool for skeletal muscle disorders: Challenges, promises, and limitations
Authors: Colapicchioni Valentina , Millozzi Francesco , Parolini Ornella , Palacios Daniela 
Published: January 2022

AbstractMuscular dystrophies are a group of rare genetic disorders characterized by progressive muscle weakness, which, in the most severe forms, leads to the patient's death due to cardiorespiratory problems. There is still no cure available for these diseases and significant effort is being placed into developing new strategies to either correct the genetic defect or to compensate muscle loss by stimulating skeletal muscle regeneration. However, the vast anatomical extension of the target tissue poses great challenges to these goals, highlighting the need for complementary strategies. Nanomedicine is an actively evolving field that merges nanotechnologies with biomedical and pharmaceutical sciences. It holds great potential in regenerative medicine, both in supporting tissue engineering and regeneration, and in optimizing drug and oligonucleotide delivery and gene therapy strategies. In this review, we will summarize the state‐of‐the‐art in the field of nanomedicine applied to skeletal muscle regeneration. We will discuss the recent work toward the development of nanopatterned scaffolds for tissue engineering, the efforts in the synthesis of organic and inorganic nanoparticles for gene therapy and drug delivery applications, as well as their use as immune modulators. Although nanomedicine holds great promise for muscle and other degenerative diseases, many challenges still need to be systematically addressed to assure a smooth transition from the bench to the bedside.This article is categorized under:
Implantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and Replacement
Coming of Age in the Secular Republic of Fiction
Authors: Verkaaik Oskar 
Published: January 2022

AbstractCriticizing the concept of culture as bounded, static and intrinsically connected to the nation, Peter van der Veer emphasized global connections and showed how global notions like the nation or religion are translated locally. This emphasis on global connections took him from India, his first ethnographic region, back to Europe—Britain and the Netherlands in particular—before he moved on to work on China. This ‘enigma of return’ perspective stirred up received ideas within the academic milieus in these countries. My aim in this chapter is to try and do something similar by returning to questions about religion, the secular and the nation after working on similar issues in Pakistan. I do this by rereading novels from the 1960s and 1970s that not only expressed changing ways of thinking and living, but also took these ideas further. I argue that the Dutch literary scene reflects the secular culture of the post-war generation, which still informs political debates about the place of religion, such as Islam, in the nation in the contemporary Netherlands. I also argue that contemporary secular culture is artistically and creatively barren in comparison to what it was in the 1960s and 1970s.
The Oeuvre of Peter van der Veer
Authors: Ahmad Irfan 
Published: January 2022

AbstractThis chapter critically evaluates the corpus of writings by Peter van der Veer, a Dutch anthropologist described by Dipesh Chakrabarty as ‘one of the foremost scholars in comparative studies of religion, nationalism, and urban life in Asia’. Divided into three parts, in part one I dwell on van der Veer’s work from 1985 to 1994, discussing his contributions to the study of Hinduism, orientalism and nationalism. In part two, I analyse his works during the second phase, that is, from 1995 to the present. Though diverse, I have arranged the analysis of these works under the overarching category of comparison. The final brief section identifies the style and mode of van der Veer’s interventions, thesine qua nonof which I call, after Nietzsche, ‘theorization with a hammer’. In the conclusion, I highlight themes and questions that van der Veer’s works do not squarely address but that gainfully work as analytical enablers of future research.
Muslim Bare Life in Contemporary India
Authors: Ahmad Irfan , van der Veer Peter 
Published: January 2022

AbstractToday Hindutva has become hegemonic to the extent that Muslims not only have to fear for their way of life but also for their own bare lives. The election of Narendra Modi as prime minister is a sign of the changes that have occurred from the Rashtriya Swayamsevak Sangh (RSS)-led Hindutva campaigns of the 1980s to the firm grip on government by the BJP-RSS today. Analyses of ‘the success of India’s democracy’ (Kohli,The Success of India’s Democracy. Cambridge: Cambridge University Press, 2001; Banerjee,Why India Votes. New Delhi: Routledge, 2014) never seem to take fully into account the importance of religion and religious divisions. This chapter attempts to address the consequences of the rise to power of Hindu civilizational nationalism.
Moral Labour, the Nation and the State in Contemporary China
Authors: He Xiao 
Published: January 2022

AbstractWhile the socialist state in China has attempted to elevate the labour of working people as a symbol of national identity, it restricts rural migrant workers’ access to public goods and equal citizenship rights. While rural migrants perform the public identity of the hard worker in order to claim both respect and benefits that go beyond legal recognition, the value of their hard work is also constrained by dubious state institutions and particularistic relationships. In rural-urban migration and market expansion, money mediates the imagination of the nation, but it also devalues rural migrants’ labour, highlighting the social inequality and disjunction between rural and urban, the rich and ordinary people, within the nation. Rural migrants imagine their inclusion in the nation through investment opportunities which always involve an opaque state.
Swampland conditions for higher derivative couplings from CFT
Authors: Kundu Sandipan 
Published: January 2022

Abstract
There are effective field theories that cannot be embedded in any UV complete theory. We consider scalar effective field theories, with and without dynamical gravity, in D-dimensional anti-de Sitter (AdS) spacetime with large radius and derive precise bounds (analytically) on the coupling constants of higher derivative interactions ϕ2□kϕ2 by only requiring that the dual CFT obeys the standard conformal bootstrap axioms. In particular, we show that all such coupling constants, for even k ≥ 2, must satisfy positivity, monotonicity, and log-convexity conditions in the absence of dynamical gravity. Inclusion of gravity only affects constraints involving the ϕ2□2ϕ2 interaction which now can have a negative coupling constant. Our CFT setup is a Lorentzian four-point correlator in the Regge limit. We also utilize this setup to derive constraints on effective field theories of multiple scalars. We argue that similar analysis should impose nontrivial constraints on the graviton four-point scattering amplitude in AdS.
Dynamics, symmetries, anomaly and vortices in a rotating cosmic string background
Authors: Inzunza Luis , Plyushchay Mikhail S. 
Published: January 2022

Abstract
Non-relativistic conformally invariant systems in a rotating cosmic string (conical) spacetime are analyzed at the classical and quantum levels by means of the gravitoelectromagnetic interpretation of the background. Solutions of the equations of motion are found by employing a local canonical transformation, that leads to their natural interpretation in terms of Riemann surfaces. The cone parameter α and the angular velocity Ω of the background determine the existence of hidden symmetries. Globally defined higher order integrals associated with perihelion of geodesic orbits appear at rational values of α. For the harmonic oscillator system with frequency ω, the integrals responsible for the trajectory closure arise only for rational values of α and |γ| = |Ω/ω|, with |γ| = 1 corresponding to the Landau problem. We face a quantum anomaly problem since the hidden symmetry operators can only be constructed when α is integer. Such operators are non-local in the case of the free particle. For the harmonic oscillator, the symmetry generators are obtained with the help of the conformal bridge transformation. We also study a multi-particle version of the harmonic oscillator system with |γ| = 1 using the mean-field theory and find that the emerging vortex structure respects a singular point of the background.
Macrophage migration inhibitory factor family proteins are multitasking cytokines in tissue injury
Authors: Song Shanshan , Xiao Zhangping , Dekker Frank J. , Poelarends Gerrit J. , Melgert Barbro N. 
Published: January 2022

AbstractThe family of macrophage migration inhibitory factor (MIF) proteins in humans consist of MIF, its functional homolog D-dopachrome tautomerase (D-DT, also known as MIF-2) and the relatively unknown protein named DDT-like (DDTL). MIF is a pleiotropic cytokine with multiple properties in tissue homeostasis and pathology. MIF was initially found to associate with inflammatory responses and therefore established a reputation as a pro-inflammatory cytokine. However, increasing evidence demonstrates that MIF influences many different intra- and extracellular molecular processes important for the maintenance of cellular homeostasis, such as promotion of cellular survival, antioxidant signaling, and wound repair. In contrast, studies on D-DT are scarce and on DDTL almost nonexistent and their functions remain to be further investigated as it is yet unclear how similar they are compared to MIF. Importantly, the many and sometimes opposing functions of MIF suggest that targeting MIF therapeutically should be considered carefully, taking into account timing and severity of tissue injury. In this review, we focus on the latest discoveries regarding the role of MIF family members in tissue injury, inflammation and repair, and highlight the possibilities of interventions with therapeutics targeting or mimicking MIF family proteins.
Matrix-Valued Truncated Toeplitz Operators: Unbounded Symbols, Kernels and Equivalence After Extension
Authors: O’Loughlin Ryan 
Published: January 2022

AbstractThis paper studies matrix-valued truncated Toeplitz operators, which are a vectorial generalisation of truncated Toeplitz operators. It is demonstrated that, although there exist matrix-valued truncated Toeplitz operators without a matrix symbol in $$L^p$$

L
p

for any $$p \in (2, \infty ]$$

p
∈
(
2
,
∞
]

, there is a wide class of matrix-valued truncated Toeplitz operators which possess a matrix symbol in $$L^p$$

L
p

for some $$p \in (2, \infty ]$$

p
∈
(
2
,
∞
]

. In the case when the matrix-valued truncated Toeplitz operator has a symbol in $$L^p$$

L
p

for some $$p \in (2, \infty ]$$

p
∈
(
2
,
∞
]

, an approach is developed which bypasses some of the technical difficulties which arise when dealing with problems concerning matrix-valued truncated Toeplitz operators with unbounded symbols. Using this new approach, two new notable results are obtained. The kernel of the matrix-valued truncated Toeplitz operator is expressed as an isometric image of an $$S^*$$

S
∗

-invariant subspace. Also, a Toeplitz operator is constructed which is equivalent after extension to the matrix-valued truncated Toeplitz operator. In a different yet overlapping vein, it is also shown that multidimensional analogues of the truncated Wiener–Hopf operators are unitarily equivalent to certain matrix-valued truncated Toeplitz operators.
Explicit Diagrammatic Solution of Normalised, Nondegenerate Rayleigh–Schrödinger Perturbation Theory
Authors: Pommerening Joel C. , DiVincenzo David P. 
Published: January 2022

AbstractWe solve the coupled recurrence relations for eigenenergies and -vectors in nondegenerate Rayleigh–Schrödinger perturbation theory under the constraint that the approximate eigenvector is normalised to 1 in every order. The series can be expressed in terms of diagrams that were first introduced by Bloch (Nucl Phys 6:329, 1958) for the degenerate, unnormalised case. Normalisation increases the number of terms and introduces a nontrivial dependence on the diagrams’ topology to the coefficients.
Blue collar with tie: a human-centered reformulation of the ironies of automation
Authors: Meisinger Norman 
Published: January 2022

AbstractWhen Lisanne Bainbridge wrote about counterintuitive consequences of the increasing human–machine interaction, she concentrated on the resulting issues for system performance, stability, and safety. Now, decades later, however, the automized work environment is substantially more pervasive, sophisticated, and interactive. Current advances in machine learning technologies reshape the value, meaning, and future of the human workforce. While the ‘human factor’ still challenges automation system architects, inconspicuously new ironic settings have evolved that only become distinctly evident from a human-centered perspective. This brief essay discusses the role of the human workforce in human–machine interaction as machine learning continues to improve, and it points to the counterintuitive insight that although the demand for blue-collar workers may decrease, exactly this labor class increasingly enters more privileged working domains and establishes itself henceforth as ‘blue collar with tie.’
Mapping the Green-Lipped Mussel (Perna canaliculus) Microbiome: A Multi-Tissue Analysis of Bacterial and Fungal Diversity
Authors: Li Siming , Young Tim , Archer Stephen , Lee Kevin , Sharma Shaneel , Alfaro Andrea C. 
Published: January 2022

AbstractPoor health and mortality events of the commercially important and endemic New Zealand green-lipped mussel (Perna canaliculus) pose a threat to its industry. Despite the known importance of microbiomes to animal health and environmental resilience, the host-associated microbiome is unexplored in this species. We conducted the first baseline characterization of bacteria and fungi within key host tissues (gills, haemolymph, digestive gland, and stomach) using high-throughput amplicon sequencing of 16S rRNA gene and ITS1 region for bacteria and fungi, respectively. Tissue types displayed distinctive bacterial profiles, consistent among individuals, that were dominated by phyla which reflect (1) a fluid exchange between the circulatory system (gills and haemolymph) and surrounding aqueous environment and (2) a highly diverse digestive system (digestive gland and stomach) microbiota. Gammaproteobacteria and Campylobacterota were mostly identified in the gill tissue and haemolymph, and were also found in high abundance in seawater. Digestive gland and stomach tissues were dominated by common gut bacterial phyla, such as Firmicutes, Cyanobacteria, Proteobacteria, and Bacteroidota, which reflects the selectivity of the digestive system and food-based influences. Other major notable taxa included the family Spirochaetaceae, and genera Endozoicomonas, Psychrilyobacter, Moritella and Poseidonibacter, which were highly variable among tissue types and samples. More than 50% of fungal amplicon sequence variants (ASVs) were unclassified beyond the phylum level, which reflects the lack of studies with marine fungi. However, the majority of those identified were assigned to the phylum Ascomycota. The findings from this work provide the first insight into healthy tissue microbiomes of P. canaliculus and is of central importance to understanding the effect of environmental changes on farmed mussels at the microbial level.