bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weighted composition operators on Hardy–Smirnov spaces
Authors: Matache Valentin 
Published: December 2022

Abstract
Operators of type f → ψf ◦ φ acting on function spaces are called weighted composition operators. If the weight function ψ is the constant function 1, then they are called composition operators. We consider weighted composition operators acting on Hardy–Smirnov spaces and prove that their unitarily invariant properties are reducible to the study of weighted composition operators on the classical Hardy space over a disc. We give examples of such results, for instance proving that Forelli’s theorem saying that the isometries of non–Hilbert Hardy spaces over the unit disc need to be special weighted composition operators extends to all non–Hilbert Hardy–Smirnov spaces. A thorough study of boundedness of weighted composition operators is performed.
Clinician factors associated with delayed diagnosis of appendicitis
Authors: Michelson Kenneth A. , McGarghan Finn L.E. , Patterson Emma E. , Waltzman Mark L. , Samuels-Kalow Margaret E. , Greco Kimberly F. 
Published: December 2022

Abstract

Objectives
To evaluate the association of clinician demographics and practice patterns with delayed diagnosis of appendicitis.

Methods
We included children with appendicitis at 13 regional emergency departments (EDs). We screened patients with a previous ED visit within 7 days for delayed diagnosis by chart review. We evaluated the association of clinician characteristics using logistic regression with random intercepts for site and clinician and delay as the outcome.

Results
Among 7,452 children with appendicitis, 105 (1.4%) had delayed diagnosis. Clinicians in the lowest quartile of obtaining blood in their general practice were more likely to have delayed diagnosis (odds ratio 4.9 compared to highest quartile, 95% confidence interval 1.8, 13.8). Clinicians’ imaging rates, specialty, sex, and experience were not associated with delayed diagnosis.

Conclusions
Clinicians who used more blood tests in their general practice had a lower risk of delayed diagnosis of appendicitis, possible evidence that lower risk tolerance has benefits.
Inhibition of miR-21 improves pulmonary vascular responses in bronchopulmonary dysplasia by targeting the DDAH1/ADMA/NO pathway
Authors: Zhong Ying , Zhang Zhiqun , Chen Xiaoqing 
Published: December 2022

Abstract
miR-21 has been confirmed to be overexpressed in neonatal rat lungs with hyperoxia-mediated bronchopulmonary dysplasia (BPD). The specific function of miR-21 in BPD is still unclear. We established the hyperoxia-induced BPD rat model in vivo and the hyperoxia-induced pulmonary microvascular endothelial cells (PMVECs) model in vitro. Transwell assay was utilized to detect the migratory capability of PMVECs. Tube formation assay was utilized to measure angiogenesis ability. ELISA was utilized to test nitric oxide (NO) production and the intracellular and extracellular Asymmetric Dimethylarginine (ADMA) concentration. Furthermore, the interaction between miR-21 and dimethylarginine dimethylaminohydrolase 1 (DDAH1) was evaluated using luciferase reporter assay. We found that miR-21 expression in PMVECs was increased by hyperoxia stimulation. Inhibition of miR-21 improved the migratory and angiogenic activities of PMVECs and overexpression of miR-21 exerted the opposite effects. Furthermore, knockdown of miR-21 increased NO production and decreased intracellular and extracellular ADMA concentration in hyperoxia-treated PMVECs. Next we proved that miR-21 could bind to DDAH1 and negatively regulate its expression. Rescues assays showed that DDAH1 knockdown reversed the effects of miR-21 depletion on hyperoxia-mediated PMVEC functions, NO production, and ADMA concentration. Importantly, miR-21 downregulation restored alveolarization and vascular density in BPD rats. This study demonstrates that inhibition of miR-21 improves pulmonary vascular responses in BPD by targeting the DDAH1/ADMA/NO pathway.
COVID-19 Y TELEDOCENCIA UNIVERSITARIA EN ESPAÑA. EL CASO PRÁCTICO DE LAS TITULACIONES DE PERIODISMO Y COMUNICACIÓN
Authors: Gómez  López Concepción 
Published: December 2022

La crisis del coronavirus modificó las rutinas laborales de todos los ámbitos profesionales,
La crisis del coronavirus modificó las rutinas laborales de todos los ámbitos profesionales, incluso el de la enseñanza universitaria con la clausura temporal de los edificios académicos. Las universidades españolas siguieron funcionando pese a la restricción de movimientos (Decreto de Estado de Alarma del 14 de marzo de 2020) ya que el profesorado modificó sus rutinas ajustando los procedimientos de su actividad docente teórico-práctica a los requerimientos de la docencia no presencial.
Este artículo es una aproximación a las percepciones y a la experiencia del profesorado universitario durante la pandemia y la etapa pospandémica. Metodológicamente se compara el estudio de caso realizado previamente en la Facultad de Ciencias Sociales y Comunicación de Pontevedra (Gómez López y Alende Castro, 2022) con los hallazgos de la presente publicación facilitados por docentes de las universidades de Navarra, Pontificia de Salamanca, Complutense de Madrid, Salamanca, Pompeu Fabra, La Laguna, Santiago de Compostela y A Coruña. El estudio conlleva una metodología mixta, con datos recogidos a partir de un cuestionario tipo y de una entrevista.
Los resultados determinan que el esfuerzo realizado por los docentes españoles y los centros de educación superior suplieron las limitaciones del aula física durante la pandemia, pero trasladando al aula virtual los recursos propios de la metodología presencial, no apreciándose, sin embargo, progresos significativos en nuevas metodologías docentes que permitan avanzar hacia modelos educativos más flexibles.
The possible influence of socio-cultural and socio-economic parameters on local languages: the case of Šalčininkai District
Authors: Čepaitienė Agnė 
Published: December 2022

The aim of the study is to use GIS tools and methods to identify the mobility trends of the members of the local communities of Šalčininkai district and surrounding areas and their impact on the local languages on the basis of socio-economic and socio-cultural parameters. The research material consists of: 1) survey data, on the basis of which the coefficients of the influence of attractions on the language were calculated; 2) statistical socio-economic data for 2020-2021; 3) geo-spatial data of Lithuania; 4) linguistic studies of Šalčininkai district. GIS tools and methods were used to assess the infrastructure of residential areas, a heat map of attractions with the greatest impact on linguistic shift was created based on the results of the survey, and a link network of Atlas of Lithuanian Language (ALL) points and infrastructures was implemented through accessibility analysis. Based on social network theory, the structure of socio-cultural networks and their influence on linguistic shift, as well as the influence of additional socio-economic and socio-cultural factors was assessed. The analysis has highlighted the linguistic, socio-economic and socio-cultural uniqueness of Šalčininkai district. The study area is a zone with a more internal mobility level: there is less migration between areas where different languages (Slavic and Lithuanian) are spoken, and more migration between different dialects (Eastern Aukštaitians of Vilnius and Southern Aukštaitians). However, due to the disappearance of ALL points in almost half of Šalčininkai district, the well-developed infrastructure in the district centre and the abundance of elderly communities in the district, the intensity of mobility is low. Therefore, all the areas surveyed can be considered socio-culturally non-isolated, but linguistically quite isolated. This ensures the survival and dominance of the Slavic language. The centre of the district – Šalčininkai (ALL 666) - is considered to be the most socio-economically and socio-culturally stable in the study area. However, this town attracts residents from socially unstable areas and residents of different dialects. This creates favourable socio-economic and socio-cultural conditions for the Slavic languages (partly also for Lithuanian dialects) to compete, but remain viable. The other ALL points in Šalčininkai district belong to the open zone, where the processes of shift in the characteristics of Slavic languages and/or Lithuanian dialects are taking place.
Coding for Pediatrics 2023: A Manual for Pediatric Documentation and Payment
Authors:   Committee on Coding and Nomenclature,   American Academy of Pediatrics
Published: December 2022

This year’s completely updated 28th edition of Coding for Pediatrics includes all changes in CPT® codes, complete with expert guidance for their application. Also included are the new changes to office and outpatient evaluation and management (E/M) coding. The book’s many clinical vignettes, examples, and coding pearls add the guidance needed to ensure accuracy and payment.
View a message from Coding for Pediatrics 2023 editor Dr Linda Parsi to learn about using this title in your practice as well as key updates to this year’s edition.
Access to this ebook also includes access to an exclusive supplementary materials site located at www.aap.org/cfp2023.
Protective and Unequal? Caregiver Presence During Pediatric Hospitalizations
Authors: Lin Karen , White Michelle J. , Holliday Katelyn M. , Parnell Lisa S. , Parente Victoria M. 
Published: December 2022

OBJECTIVES:
Describe the association between caregiver presence on hospital day 1 and outcomes related to readmissions, pain, and adverse events (AE).

METHODS:
Caregiver presence during general pediatrics rounds on hospital day 1 was recorded, along with demographic data and clinical outcomes via chart review. AE data were obtained from the safety reporting system. χ2 tests compared demographic characteristics between present and absent caregivers. Background elimination determined significant predictors of caregiver presence and their association with outcomes.

RESULTS:
A total of 324 families were assessed (34.9% non-Hispanic white, 41.4% Black, 17% Hispanic or Latinx, 6.8% other race or ethnicity). Adolescents (aged ≥14 years) had increased odds of not having a caregiver present compared with 6- to 13-year-olds (36.2% vs 10%; adjusted odds ratio [aOR] 5.11 [95% confidence interval (CI) 1.88–13.87]). Publicly insured children were more likely to not have a caregiver present versus privately insured children (25.1% vs 12.4%; aOR 2.38 [95% CI 1.19–4.73]). Compared with having a caregiver present, children without caregivers were more likely to be readmitted at 7 days (aOR 3.6 [95% CI 1.0–12.2]), receive opiates for moderate/severe pain control (aOR 11.5 [95% CI 1.7–75.7]), and have an AE reported (aOR 4.0 [95% CI 1.0–15.1]).

CONCLUSIONS:
Adolescents and children with public insurance were less likely to have a caregiver present. Not having a caregiver present was associated with increased readmission, opiate prescription, and AE reporting. Further research is needed to delineate whether associations with clinical outcomes reflect differences in quality of care and decrease barriers to caregiver presence.
Music Analysis as a Description of Eventing in Time: A Phenomenological Description of Bartók's Improvisation op. 20 no. 3
Authors: Mohammad Iyad A. 
Published: December 2022

AbstractThis article offers a phenomenological description of Béla Bartók's Improvisation op. 20 no. 3, with a focus on temporality as experienced in listening. Such a description aims at understanding the structure of eventings, through which we encounter and experience, grasp and take up the work's Gestalt in time as a singular dynamic whole, which is its being as becoming, its presentation in its idea and form. As a result, what we hear, perceive and understand as we listen to the work is revealed as the unfolding of a complex network of intersecting eventings, the crossing of contrarily directed motions, interpenetration of intonations and gestures, circularities on different perceptual levels from delaying and returning notes, intonations, gestures and themes, to thematic repetition and variation, their recallings and cross-referencing. These micro-eventings yield eventings on a larger perceptual level that include ternarity, cyclicity in its broadest sense and a concentric concave-shaped contour. This is the work's Gestalt; the unique balance as ratio, correlation and interrelation, not equilibrium, of all these eventings and temporalities.
Before The Wooden Prince: Károly Szabados's Ballet Vióra (1891) in the Context of the History of Hungarian Ballet
Authors: Ujvári Hedvig 
Published: December 2022

AbstractFollowing the debut of Károly Szabados's ballet Vióra on March 14, 1891, the daily newspaper Pesti Hírlap called the date a glorious day not only for Hungarian music, but also for Hungarian genius and spirit in general, and treated the debut at the Hungarian Royal Opera House in Budapest as an allegory for spring: “It was as if the refreshing, revitalizing breaths of that traditional March breeze had blown across the hall of muses on Andrássy Road: such was the enthusiasm dominating the spectators' benches and the stage alike.”1 According to the newspaper, it was the long-anticipated victory of “the Hungarian genius, which some had begun to consider as almost alien to the Hungarian royal theater,” and it was all thanks to Géza Zichy (1849–1924), one of whose first acts as intendant was bringing this long neglected piece to the stage.2 In the context of Vióra's premiere, the “Hungarian genius” and the “Hungarian spirit” manifested on several levels, as it was the decision of a Hungarian intendant to present the evening-long ballet of a Hungarian author revolving around Hungarian themes; but this raises the question, why did a Hungarian ballet carry such significance at the time? What place does Károly Szabados, the author of the ballet, occupy in the history of Hungarian music, and how was the ballet and its music received by contemporaries in and out of the limelight? This study attempts to answer these questions by examining contemporary Hungarian and German news articles and music critiques published in Budapest.
Legende und Wirklichkeit •
Authors: Enyedi Pál 
Published: December 2022

AbstractThis study examines the earliest data of the history of the organ in Transylvania collected in the past one hundred and fifty years. A thorough examination proved that data, based on incomplete documentation, on erroneous hypotheses or conclusions, had been quite unprofessionally put into contexts to which they had no proven connection. Thus, legends regarding the first representation of an organ, the first organ, the earliest organ builders etc. appeared in the costume of historicity and were widely circulated among different authors.
Attilio Ariosti as a Composer of Vocal Duets
Authors: Ćurković Ivan 
Published: December 2022

AbstractIn the first seasons of the Royal Academy of Music in London, its directors saw George Frideric Handel as one among several composers whose style reflected expectations of what Italian opera in London should be like. At one point, Handel’s slightly older Italian contemporaries Giovanni Bononcini and Attilio Ariosti were in equal positions to compete for success. This paper will focus on Attilio Ariosti as the seemingly most moderate party in the rivalry between the three composers to see if the specificities of the centers he was active in affected his output in the realm of the vocal duet, a less common and somewhat less important constituent of dramatic vocal genres as opposed to the dominant arias. The examination of duets in some of Ariosti’s works written for Berlin, Vienna, and London, and some comparisons with the duets by both Bononcini and Handel will shed a light on these relationships affected by competition and rivalry.
Pengembangan Kapasitas Nelayan Tangkap Gillnet Di Dusun Talaga Nipa, Kabupaten Seram Bagian Barat
Authors: Haruna Haruna , Tawari Ruslan H.S. , Sangadji Selfi 
Published: December 2022

Kegiatan pengabdian ini bertujuan memberikan pemahaman dan pengetahuan kepada nelayan jaring insang dasar pada aspek teknis, bio-ekologi, dan manajemen pengelolaan perikanan berkelanjutan di Dusun Talaga Nipa Kabupaten, Seram Bagian Barat. Prosedur kegiatan menerapkan metode eksperimental fishing terhadap tiga ukuran mata jaring 1,75 inch, 2,0 inch, 2,25 inch 3 inch. Konstruksi dan pengoperasian alat tangkap dilakukan bersama dengan nelayan. Komposisi hasil tangkapan jaring insang terdiri dari 7 spesies. Distribusi ikan sampel yaitu ikan kembung (Rasterlliger kanagurta) pada ukuran 21,5-31,5 cm, dan ukuran dominan mata jaring 2,0 inch adalah 24,5 cm, sedangkan mata jaring 2,25 dan 2,5 inch adalah 25,5 cm. Proporsi tertangkap optimum pada mata jaring 2,0 inch adalah 23,35 cm, mata jaring 2,25 inch adalah 26,27 cm, dan mata jaring 2,5 inch adalah 27,62 cm. Tahapan diskusi dan sharing berdasarkanhasil analisis ini menunjukkan nelayan telah memahami tentang keberlanjutan sumberdaya perikanan keterkaitannya secara teknis alat tangkap, bio-ekologi, dan manajemen pengelolaan. Hasil kegiatan ini diharapkan dapat menjadi pengetahuan sehingga keberlanjutan sumberdaya perikanan di wilayah pesisir pantai optimal.
SYNTHESIS AND PHOTOLUMINESCENCE PROPERTIES OF ELLIPSOIDAL La2O2SO4:Eu3+ PHOSPHORS
Authors: Li Xing , Gao Lutong , Lian Jingbao 
Published: December 2022

This research was focused on the homogeneous precipitation synthesis of a series of Eu3+ ion-activated ellipsoidal La2O2SO4 phosphors based on the La2(SO4)3-CO(NH2)2 reaction system. The structural identification, thermal analysis, morphology and luminescence properties of the as-prepared products were characterized with Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), thermogravimetry and differential scanning calorimetry (TG/DSC), field emission scanning electron microscopy (FESEM) and photoluminescence (PL) spectra. Pure La2O2SO4 ellipsoidal particles with a long radius of about 2 µm and a short radius of about 1 µm were successfully prepared by calcining a rhombus-like precursor at 800 °C for 2 h in air. The formation mechanism of the precursor and its corresponding calcination product were also proposed. Photoluminescence results revealed that the strongest red emission peak was centered at 619 nm upon 249-nm ultraviolet (UV) light excitation in La2O2SO4:x%Eu3+ (x = 3, 6, 9, 12 and 15) phosphors. The exchange interaction was responsible for the concentration quenching mechanism of the 5D0→7F2 transition of Eu3+ ions in the La2O2SO4 host lattice. The optimal x value was 15 and the corresponding decay process showed a single exponential decay behavior whose lifetime t and color correlation temperature (CCT) were calculated to be 2.112 ms and 2752 K, respectively.
<i>NF-Y</i> genes in the somatic embryo development
Authors: Potsenkovskaia Elina A. , Tvorogova Varvara E. , Lutova Ludmila A. 
Published: December 2022

For many important legumes, protocols for their efficient transformation and regeneration have not yet been developed. Somatic embryogenesis (SE) the embryo development from somatic cells has an important application in biotechnology: reproduction and obtaining of transgenic plants.
There are transcription factors involved in embryogenesis processes, which can stimulate the development of somatic embryos, such as the LEC1 gene in Arabidopsis thaliana.
The LEC1 belongs to the NF-YB family. NF-YB together with NF-YA and NF-YC subunits form heterotrimeric complex NF-Y. In plants, each subunit is encoded by several genes, and combinations of different subunits are able to regulate various processes in plant.
We hypothesized that the LEC1 orthologues in legumes can stimulate SE in combination with specific NF-YA and C subunits. The aim of our study was to find new SE regulators among NF-Y genes in legumes.
In the model legume object Medicago truncatula we find NF-Y genes highly expressed during SE. Among these genes, potential LEC1 partners were selected with the use of the yeast two-hybrid system. Analysis of calli with overexpression of LEC1 orthologues didnt demonstrate increased SE capacity, but overexpression of one of the NF-YA genes increased callus weight.
We are planning to investigate the effect of co-overexpression of NF-YA, B and C genes on the regeneration processes.
This work was supported by the Ministry of Science and Higher Education of the Russian Federation in accordance with agreement No. 075-15-2022-322 date 22.04.2022 on providing a grant in the form of subsidies from the Federal budget of Russian Federation. The grant was provided for state support for the creation and development of a World-class Scientific Center Agrotechnologies for the Future.
Methylotrophic yeast Komagataella phaffii as Neoleukin producer
Authors: Makeeva Anastasia S. , Shubert Maria A. , Al Shanaa Ousama , Rumyantsev Andrei M. 
Published: December 2022

Methylotrophic yeast Komagataella рhaffii (also known as Pichia pastoris) is widely applied in biotechnology for recombinant protein production. K. рhaffii particularly proved to be a successful host system for the synthesis of immunomodulators such as interferons [1].
In this study, we engineered K. рhaffii strains capable of producing the immunomodulatory protein Neoleukin (Neo-2/15). Neo-2/15 is an interleukin-2 mimetic, designed by in silico methods [2]. In preclinical studies on murine cancer models, Neo-2/15 showed superior therapeutic effect to inerleukin-2 with reduced toxicity.
In this work, we show that K. рhaffii can successfully synthesize and secrete Neo-2/15. We have obtained a number of K. phaffii strains, including MutS and Mut+, with different Neo-2/15 expression cassettes integrated into the genome, carrying up to five copies of Neo-2/15 gene. In fact, the higher number of Neo-2/15 gene copies in K. рhaffii genome allowed a higher protein yield.
In this study, we further developed a split marker approach [3] for yeast transformation using two DNA fragments, comprising of the expression cassette and the overlapping fragments of the marker gene. This allowed us to generate MutS strains with two copies using pPICZB vector, which is not originally intended for MutS strain generation.
As a result, we demonstrated that K. phaffii is a perspective producer of Neo-2/15, providing wide opportunities to increase the production of this therapeutic protein.