bluuebunny/crossref_metadata_2025_split huggingface dataset:
Control of a Wheelchair-Mounted 6DOF Assistive Robot With Chin and Finger Joysticks
Authors: Rulik Ivan , Sunny Md Samiul Haque , Sanjuan De Caro Javier Dario , Zarif Md Ishrak Islam , Brahmi Brahim , Ahamed Sheikh Iqbal , Schultz Katie , Wang Inga , Leheng Tony , Longxiang Jason Peng , Rahman Mohammad H. 
Published: July 2022

Throughout the last decade, many assistive robots for people with disabilities have been developed; however, researchers have not fully utilized these robotic technologies to entirely create independent living conditions for people with disabilities, particularly in relation to activities of daily living (ADLs). An assistive system can help satisfy the demands of regular ADLs for people with disabilities. With an increasing shortage of caregivers and a growing number of individuals with impairments and the elderly, assistive robots can help meet future healthcare demands. One of the critical aspects of designing these assistive devices is to improve functional independence while providing an excellent human–machine interface. People with limited upper limb function due to stroke, spinal cord injury, cerebral palsy, amyotrophic lateral sclerosis, and other conditions find the controls of assistive devices such as power wheelchairs difficult to use. Thus, the objective of this research was to design a multimodal control method for robotic self-assistance that could assist individuals with disabilities in performing self-care tasks on a daily basis. In this research, a control framework for two interchangeable operating modes with a finger joystick and a chin joystick is developed where joysticks seamlessly control a wheelchair and a wheelchair-mounted robotic arm. Custom circuitry was developed to complete the control architecture. A user study was conducted to test the robotic system. Ten healthy individuals agreed to perform three tasks using both (chin and finger) joysticks for a total of six tasks with 10 repetitions each. The control method has been tested rigorously, maneuvering the robot at different velocities and under varying payload (1–3.5 lb) conditions. The absolute position accuracy was experimentally found to be approximately 5 mm. The round-trip delay we observed between the commands while controlling the xArm was 4 ms. Tests performed showed that the proposed control system allowed individuals to perform some ADLs such as picking up and placing items with a completion time of less than 1 min for each task and 100% success.
The impact of a group based, remotely delivered weight loss intervention in women with polycystic ovary syndrome on ovulation, quality of life and body composition
Authors: Gorczyca Anna M. , Steger Felicia L. , Ptomey Lauren T. , Montgomery Robert N. , Mickelsen Riley , Smith Patricia , Donnelly Joseph E. , Marsh Courtney A. 
Published: July 2022

BackgroundObesity and visceral adiposity are associated with anovulation. The most common cause of anovulatory infertility in women of reproductive age is polycystic ovary syndrome (PCOS). We conducted this formative study to examine the effects of a remotely delivered, group-based lifestyle program for women with overweight/obesity and PCOS on ovulation, PCOS related quality of life (PCOSQ) and body composition.MethodsWomen with anovulatory infertility caused by PCOS (N = 12) were enrolled in a 6-month high-intensity weight management intervention. Participants were asked to attend 45 min., group behavioral lifestyle sessions, delivered remotely by a registered dietitian weekly across the 6-mo. study and comply with a reduced energy diet, increased physical activity (225 min/wk.), and self-monitoring of weight, physical activity and diet. Diets consisted of five portion-controlled meals (three shakes + two entrees), at least five servings of fruits/vegetables, and ad libitum non-caloric beverages daily. Wilcoxon signed-rank tests were used to assess changes in outcomes across the intervention.ResultsTwelve women received the weight loss intervention (mean age = 32.7 ± 4.2 yrs., BMI = 36.8 ± 4.5 kg/m2, 92% college educated), and 8 completed the intervention. Eight (67%) women reported ovulating during the intervention with an average time to ovulation of 57 ± 45 days. Women lost an average of 3.85 ± 5.94 kg (p = 0.02), decreased their BMI (−1.61 ± 1.09 kg/m2; p = 0.04), and waist circumference (−4.54 ± 3.03 cm; p = 0.04) over the 6-mo. intervention. Additionally, self-reported menstrual problems measured by PCOSQ significantly improved over the study (p = 0.03).ConclusionA multicomponent group-based, remotely delivered, lifestyle intervention delivered remotely is a feasible and potentially scalable option to achieve clinically relevant (&gt;3%) weight loss in women with PCOS.Clinical trial registrationwww.clinicaltrials.gov, identifier: NCT03677362.
Assessment of a novel smartglass-based point-of-care fusion approach for mixed reality-assisted targeted prostate biopsy: A pilot proof-of-concept study
Authors: Sparwasser P. , Haack M. , Frey L. , Boehm K. , Boedecker C. , Huber T. , Stroh K. , Brandt M. P. , Mager R. , Höfner T. , Tsaur I. , Haferkamp A. , Borgmann H. 
Published: July 2022

PurposeWhile several biopsy techniques and platforms for magnetic resonance imaging (MRI)-guided targeted biopsy of the prostate have been established, none of them has proven definite superiority. Augmented and virtual reality (mixed reality) smartglasses have emerged as an innovative technology to support image-guidance and optimize accuracy during medical interventions. We aimed to investigate the benefits of smartglasses for MRI-guided mixed reality-assisted cognitive targeted biopsy of the prostate.MethodsFor prospectively collected patients with suspect prostate PIRADS lesions, multiparametric MRI was uploaded to a smartglass (Microsoft® Hololens I), and smartglass-assisted targeted biopsy (SMART TB) of the prostate was executed by generation of a cognitive fusion technology at the point-of-care. Detection rates of prostate cancer (PCA) were compared between SMART TB and 12-core systematic biopsy. Assessment of SMART-TB was executed by the two performing surgeons based on 10 domains on a 10-point scale ranging from bad (1) to excellent (10).ResultsSMART TB and systematic biopsy of the prostate were performed for 10 patients with a total of 17 suspect PIRADS lesions (PIRADS 3, n = 6; PIRADS 4, n = 6; PIRADS 5, n = 5). PCA detection rate per core was significant (p &lt; 0.05) higher for SMART TB (47%) than for systematic biopsy (19%). Likelihood for PCA according to each core of a PIRADS lesion (17%, PIRADS 3; 58%, PIRADS 4; 67%, PIRADS 5) demonstrated convenient accuracy. Feasibility scores for SMART TB were high for practicality (10), multitasking (10), execution speed (9), comfort (8), improvement of surgery (8) and image quality (8), medium for physical stress (6) and device handling (6) and low for device weight (5) and battery autonomy (4).ConclusionSMART TB has the potential to increase accuracy for PCA detection and might enhance cognitive MRI-guided targeted prostate biopsy in the future.
Antitumor Effects of Cannabinoids in Human Pancreatic Ductal Adenocarcinoma Cell Line (Capan-2)-Derived Xenograft Mouse Model
Authors: Sakarin Siriwan , Meesiripan Nuntana , Sangrajrang Suleeporn , Suwanpidokkul Nuntakan , Prayakprom Piyaporn , Bodhibukkana Chatchada , Khaowroongrueng Vipada , Suriyachan Kankanit , Thanasittichai Somchai , Srisubat Attasit , Surawongsin Pattamaporn , Rattanapinyopituk Kasem 
Published: July 2022

BackgroundPancreatic cancer is considered a rare type of cancer, but the mortality rate is high. Cannabinoids extracted from the cannabis plant have been interested as an alternative treatment in cancer patients. Only a few studies are available on the antitumor effects of cannabinoids in pancreatic cancer. Therefore, this study aims to evaluate the antitumor effects of cannabinoids in pancreatic cancer xenografted mouse model.Materials and MethodsTwenty-five nude mice were subcutaneously transplanted with a human pancreatic ductal adenocarcinoma cell line (Capan-2). All mice were randomly assigned into 5 groups including negative control (gavage with sesame oil), positive control (5 mg/kg 5-fluorouracil intraperitoneal administration), and cannabinoids groups that daily received THC:CBD, 1:6 at 1, 5, or 10 mg/kg body weight for 30 days, respectively. Xenograft tumors and internal organs were collected for histopathological examination and immunohistochemistry.ResultsThe average tumor volume was increased in all groups with no significant difference. The average apoptotic cells and caspase-3 positive cells were significantly increased in cannabinoid groups compared with the negative control group. The expression score of proliferating cell nuclear antigen in positive control and cannabinoids groups was decreased compared with the negative control group.ConclusionsCannabinoids have an antitumor effect on the Capan-2-derived xenograft mouse model though induce apoptosis and inhibit proliferation of tumor cells in a dose-dependent manner.
The Seroprevalence and Hidden Burden of Chikungunya Endemicity and Malaria Mono- and Coinfection in Nigeria
Authors: Asaga Mac Peter , Airiohuodion Philomena E. , Yako Andrew B. , Makpo James K. , Kroeger Axel 
Published: July 2022

Background: Mosquito-borne infections are of global health concern because of their rapid spread and upsurge, which creates a risk for coinfections. Chikungunya, an arbovirus disease transmitted by Aedes aegypti or A. albopictus, and malaria, a parasitic disease transmitted by Anopheles gambiae, are prevalent in Nigeria and neighbouring countries, but their burden and possible coinfections are poorly understood. In this study, we investigated the seroprevalence, hidden burden and endemicity of chikungunya and malaria in three regions in Nigeria. Methods: A cross-sectional sero-survey was conducted on 871 participants in three regions of Nigeria. The samples were collected from outpatients employing simple random sampling. All serum sample analyses were performed using CHIKV virus-like particle recomLine Tropical Fever for the presence of arboviral antibody serological marker IgG immunoblot for chikungunya and malaria RDT (Rapid Diagnostic Test) for malaria parasites. Results: The seroprevalences of chikungunya and malaria mono-infection were 64.9% and 27.7%, respectively, while the coinfection seroprevalence was 71.9%. The central (69.5%) and northern (67.0%) regions showed more significant seroprevalences than the southern region (48.0%). The seroprevalence and the hidden burden of chikungunya and malaria infections varied across the three geographical regions. Conclusions: This study highlighted an unexpectedly high seroprevalence and hidden endemicity of chikungunya and a less surprising high malaria endemicity in three regions of Nigeria.
Spontaneous and Ionizing Radiation-Induced Aggregation of Human Serum Albumin: Dityrosine as a Fluorescent Probe
Authors: Radomska Karolina , Wolszczak Marian 
Published: July 2022

The use of spectroscopic techniques has shown that human serum albumin (HSA) undergoes reversible self-aggregation through protein–protein interactions. It ensures the subsequent overlapping of electron clouds along with the stiffening of the conformation of the interpenetrating network of amino acids of adjacent HSA molecules. The HSA oxidation process related to the transfer of one electron was investigated by pulse radiolysis and photochemical methods. It has been shown that the irradiation of HSA solutions under oxidative stress conditions results in the formation of stable protein aggregates. The HSA aggregates induced by ionizing radiation are characterized by specific fluorescence compared to the emission of non-irradiated solutions. We assume that HSA dimers are mainly responsible for the new emission. Dityrosine produced by the intermolecular recombination of protein tyrosine radicals as a result of radiolysis of an aqueous solution of the protein is the main cause of HSA aggregation by cross-linking. Analysis of the oxidation process of HSA confirmed that the reaction of mild oxidants (Br2•−, N3•, SO4•−) with albumin leads to the formation of covalent bonds between tyrosine residues. In the case of •OH radicals and partly, Cl2•−, species other than DT are formed. The light emission of this species is similar to the emission of self-associated HSA.
Efecto de la capacitación sobre autocuidado de niños y adolescentes con DM1 en el conocimiento del personal de enfermería
Authors: Chávez Valle Hilda Noemí , González Ofarrill Santa Caridad , Zayas Torriente Georgina María , Araujo Herrera Orlando , Rodríguez Salvá Armando , Jordán Quintans Ana Marlene 
Published: July 2022

La diabetes mellitus tipo 1 se encuentra entre las enfermedades no trasmisibles más frecuentes de la infancia. La educación terapéutica que ejerce el personal de enfermería durante la hospitalización juega un papel importante en el autocuidado, por tal motivo deben de mantener una capacitación activa. El objetivo fue evaluar el efecto de la capacitación sobre autocuidado de niños y adolescentes con diabetes mellitus tipo 1 en el conocimiento del personal de enfermería. Estudio descriptivo longitudinal, en 100 enfermeros del Hospital Pediátrico Centro Habana, mediante muestreo no probabilístico de tipo intencional por conveniencia. Se aplicó test de conocimiento antes y después de la capacitación. Se realizó prueba no paramétrica de los rangos con signos de Wilcoxon para medidas pareadas. El 57 % del personal de enfermería era técnico. El 58 % tenía más de 10 años de experiencia laboral y el 100 % no había recibido capacitación en diabetes. El pre- test arrojó conocimiento bajo en 100 % de los enfermeros, mientras que el post test después de la capacitación arrojó conocimiento alto en el 80 %. La capacitación tuvo un efecto favorable en el conocimiento del personal de enfermería sobre el autocuidado de los niños y adolescentes con diabetes mellitus tipo 1.
Palabras clave: autocuidado; capacitación; diabetes mellitus tipo 1; educación continua; niños y adolescentes.
Blast Plasmocytoid Dendritic Cell Neoplasia – Diagnosis and Results of the First Stage of Treatment (Clinical Observations)
Authors: Рукавицын О.А. , Клеина И.В. , Новосельцева Л.Г. , Филиппович Т.В. , Смирнов Р.Н. , Алексеев С.А. , Троян В.Н. 
Published: July 2022

Бластная плазмоцитоидная дендритно-клеточная неоплазия – редкое заболевание, исходящее из плазмоцитоидных дендритных клеток. В статье приведены данные, характеризующие процесс диагностики и лечения двух пациентов, почти одновременно поступивших в клинику. На первом этапе лечение оказалось успешным. Сделан акцент на необходимости накопления информации, что должно привести к формированию стандартных подходов к терапии этой редкой гематологической опухоли.
Blast plasmocytoid dendritic cell neoplasia is a rare disease originating from plasmocytoid dendritic cells. The data characterizing the process of diagnosis and treatment of two patients admitted to the clinic almost simultaneously are presented. At the first stage, the treatment was successful. Emphasis is placed on the need to accumulate information, which should lead to the formation of standard approaches to the treatment of this rare hematological tumor.
Local structure analysis of BiFeO3-BaTiO3 solid solutions
Authors: Yoneda Yasuhiro , Kim Sangwook , Mori Shigeo , Wada Satoshi 
Published: July 2022

Abstract
The average and local structures of solid solutions of (1 – x)BiFeO3–xBaTiO3 were investigated. At room temperature, pseudo-cubic phases appear in BaTiO3 compositions with x values ranging from 0.3 to 0.7. The ferroelectricity was not lost even in the cubic structure with the highest ferroelectricity observed at x = 0.3. We used a pair distribution function and an X-ray absorption fine structure to perform a structural analysis to determine the source of this ferroelectricity. These solid solutions’ local structures were consistent with the pure limits of BiFeO3 and BaTiO3, respectively, but when the composition of BaTiO3 was 0.3, a structure peculiar to the structural boundary in the solid solutions appeared. We discovered that the structure had the greatest randomness around this composition by performing a model fit of this local structure. Local structure changes to improve nanoscale dipole interactions while maintaining the ferroelectric long-range order structure. As a result, the domain size grows and the ferroelectricity improves.
A bibliometric study of AI techniques in Antenna Research over three decades
Authors: MANI GULLAPURAM 
Published: July 2022

<p> The present study uses bibliometric analysis of about 6000 documents over the period 1991-2020 to look at the growth profile of Antenna research in relation to Genetic Algorithms, Artificial Neural networks, Deep Learning, Machine Learning, Swarm Intelligence, Automation, and Robotics. The objective of the study is to help the veteran to recap old thoughts and also a new researcher to obtain an overview of the research trends in antennas and associated fields, which could be helpful in planning his research activity</p>
Carrierless Amplitude and Phase Modulation for Terahertz Communications
Authors: Shehata Mohamed , Wang Ke (Desmond) , Withayachumnankul Withawat 
Published: July 2022

<p>Terahertz communications has been foreseen as a key enabler to the sixth generation (6G) of wireless communications systems. However, the design of spectrally-efﬁcient waveforms and modulation schemes is an ongoing challenge in this regime. In this paper, we propose and experimentally demonstrate the transmission of M-ary carrierless amplitude and phase (CAP) modulated signals using a 253 GHz photo-mixing-based terahertz wireless communications system combined with the optical transmission over a 10-km standard single mode ﬁber (SSMF). Experimental results show that the CAP modulation technique has a capability to support the high-speed transmission of terahertz signals over a wide range of data rates from 4 Gbit/s to 96 Gbit/s based solely on optical intensity modulation at the transmitter side and terahertz envelope detection at the receiver side. Consequently, M-ary CAP can potentially be adopted as a low-complexity waveform and modulation contender to simplify the transceivers architectures for the sixth generation (6G) terahertz communications systems, without sacriﬁcing the high throughput targeted by these systems.</p>
BLENDED LEARNING: THE “NEW NORMAL” IN EDUCATION DELIVERY
Authors: Tom Foley  , Alicia Curtin  
Published: July 2022

Successful blended learning contexts engage students in highly interactive virtual learning environments through a mix of online and face-to-face teaching, learning and assessment modalities. This paper explores some of the affordances and constraints of blended learning for one Higher Education Institution in Ireland. TPACK (Mishra & Koehler, 2006) and Multimodal (Picciano, 2009) models frame the discussion opportunities and challenges more broadly for blended learning instructional and pedagogical design post pandemic in Higher Education.
A HYBRID INTERNATIONAL CO-TEACHING MODEL: CASE STUDY FOR BIOMEDICAL ENGINEERING DEGREE
Authors: Garcia-Zapirain Begonya , Mendez-Zorrilla Amaia , Lago-Vilariño Ana Belen 
Published: July 2022

Degrees in Biomedical Engineering are increasingly present among the international offer. The study plans of each of them allow to provide a certain specialization towards the different sub-areas within biomedical engineering through electives: orthopedics, microbiology, robotics, biosensors or artificial intelligence applied to clinical data. The fact of including 4 subjects of artificial intelligence is another of the particularities and/or differential elements of the curriculum. The University of Deusto offers a new degree in Biomedical Engineering of 240 ECTS where all the subjects of the "Bio" subject are taught in English, and include "master class" among other teaching methodologies. The teaching modality is hybrid, with a module of 24 ECTS dedicated to state-of-the-art frameworks in bioengineering that is entirely taught virtually and where international experts in each subject participate as online teachers. This is what we call "international co-teaching" which allows students to have a more realistic view of the use of technologies for biomedical applications but in an international framework. These teaching modules will follow a methodology that will combine synchronous videoconference sessions by international experts with an asynchronous methodology that includes the use of gamified activities for both content presentation and evaluation. Moreover, the teaching modules will be designed and developed according to a number of learning cycles that promote the development of the independent and meaningful learning of students and promotes the development of their knowledge, skills, attitudes, competences and values. Each learning cycle has five stages: experiential context, reflective observation, conceptualisation, active experimentation and assessment. These stages facilitate students' active construction of the learning content and the meaningful integration of that knowledge that will allow subsequent recovery, application and transfer.
Meningkatkan Hasil Belajar Pendidikan Kewarganegaraan pada Materi Sistem Hukum dan Peradilan di Indonesia melalui Penggunaan Media Audiovisual untuk Membentuk Karakter Berpikir Kritis Siswa Kelas XI MIA 3 SMAN 1 Tenggarong Tahun Pelajaran 2021-2022
Authors: Jiati Jiati 
Published: July 2022

Setiap anggota masyarakat sangat mendambakan seluruh masyarakatnya dipersiapkan untuk menjadi warganegara yang baik dan dapat berpartisipasi dalam kehidupan masyarakat dan negaranya. Namun pada pembelajaran PKN tentang system hukum dan peradilan di Indonesia, hal itu telah terdeteksi oleh peneliti dari hasil belajar siswa yang rendah. Pendidikan Kewarganegaraan seharusnya menjadi perhatian utama.Tidak ada tugas yang lebih penting dari pengembangan warganegara yang bertanggung jawab, efektif dan terdidik. Tujuan penelitian ini untuk mengetahui bahwa dengan penggunaan media audiovisual dapat meningkatkan hasil belajar PKn siswa kelas XI MIA 3 di SMA Negeri 1 Tenggarong pada materi sistem hukum dan peradilan di Indonesia. Penelitian ini menggunakan metode penelitian tindakan kelas. Hasil penelitian menunjukkan bahwa media audivisual dapat meningkatkan hasil belajar siswa kelas XI MIA 3 SMA Negri 1 Tenggarong Kabupaten Kutai Kartanegara ditunjukkan dengan ketuntasan belajar (hasil belajar) baik secara individu maupun klasikal.
O lixo eletrônico e seus riscos à saúde: uma abordagem voltada para a Educação Básica
Authors: De Oliveira Souza Kauany Andressa , Loureiro Santos Alcides 
Published: July 2022

As metodologias de ensino consideradas tradicionais estão sendo gradativamente substituídas por novas abordagens de ensino, de modo a integrar diversas áreas do conhecimento por meio de determinados temas. A temática do lixo eletrônico, presente na proposta do novo Currículo do estado do Acre, busca desenvolver competências e habilidades que estimulem o estudante a pensar de forma crítica e reflexiva, além de identificar os riscos à saúde causados pela composição química de objetos do cotidiano. Este trabalho tem como objetivo relatar como a aplicação de uma aula desenvolvida à luz da BNCC, trabalhando os riscos à saúde das pessoas e do meio ambiente, enfatizado os conhecimentos químicos envolvidos. A aula foi realizada de forma remota e contou com a participação de estudantes de química, professores da UFAC e de outras instituições. Percebeu-se que os estudantes não possuíam conhecimento prévio sobre o assunto e que não descartavam adequadamente o lixo eletrônico. Por meio de um questionário, verificou-se que mesmo após a discussão da temática na aula, nem todos os participantes se demonstraram conscientes dos impactos negativos causados pela omissão quanto ao manuseio e o descarte inadequado dos resíduos eletrônicos.