bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk for lung-related diseases associated with welding fumes in an occupational population: Evidence from a Cox model
Authors: Li Guangming , Jiang Jinfeng , Liao Yonggang , Wan Siyu , Yao Yong , Luo Yongbin , Chen Xuyu , Qian Huiling , Dai Xiayun , Yin Wenjun , Min Zhiteng , Yi Guilin , Tan Xiaodong 
Published: August 2022

BackgroundWelding fumes are a risk factor for welder pneumoconiosis. However, there is a lack of population information on the occurrence of welding fume-induced lung cancer, and little is known about the welding fume pathogenesis.MethodsWelding fume and metal ion concentrations were assessed in a vehicle factory in Wuhan. A Cox regression model estimated lung-related disease risk in workers by independent and combined factors.ResultsWorkers' exposures were divided into four grades; the highest exposure was among the welders in the maintenance workshop, the highest Mn and Fe exposure was 4 grades, and the highest Cr exposure was 3 grades. Subgroup analysis found that the risk of lung-related disease was 2.17 (95% CI: 1.31–3.57, p &lt; 0.05) in welders compared with non-welders, and the risk of pulmonary disease in male welders was 2.24 (95% CI: 1.34–3.73, p &lt; 0.05) compared to non-welders. Smoking welders had a 2.44 (95% CI: 1.32–4.51, p &lt; 0.01) higher incidence of lung-related diseases than non-welders. Total years of work as an independent protective factor for lung-related disease risk was 0.72 (95% CI: 0.66–0.78, p &lt; 0.01). As an independent risk factor, high-high and high-low exposure had a 5.39 (95% CI: 2.52–11.52, p &lt; 0.001) and 2.17 (95% CI: 1.07–4.41, p &lt; 0.05) higher risk for lung-related diseases, respectively.ConclusionsHigh welding fume exposure is a significant risk factor for lung-related disease in workers.
Determinants of maternal near-miss among women admitted to public hospitals in North Shewa Zone, Ethiopia: A case-control study
Authors: Teshome Hana Nigussie , Ayele Esubalew Tesfahun , Hailemeskel Solomon , Yimer Osman , Mulu Getaneh Baye , Tadese Mesfin 
Published: August 2022

BackgroundA maternal near-miss (MNM) refers to a woman who presents with life-threatening complications during pregnancy, childbirth, or within 42 days of termination of pregnancy but survived by chance or due to the standard care she received. It is recognized as a valuable indicator to examine the quality of obstetrics care as it follows similar predictors with maternal death. Ethiopia is one of the sub-Saharan African countries with the highest rate of maternal mortality and morbidity. Thus, studying the cause and predictors of maternal near-miss is vital to improving the quality of obstetric care, particularly in low-income countries.ObjectiveTo identify determinants of maternal near-miss among women admitted to public hospitals in North Shewa Zone, Ethiopia, 2020.MethodsA facility-based unmatched case-control study was conducted on 264 women (88 cases and 176 controls) from February to April 2020. Data were collected using pretested interviewer-administered questionnaires and a review of medical records. Data were entered into Epi-data version 4.2.2 and exported to SPSS version 25 for analysis. Variables with a p-value &lt;0.25 in the bivariable analysis were further analyzed using multivariable logistic regression analysis. Finally, variables with a p-value &lt;0.05 were considered statistically significant.ResultSevere pre-eclampsia (49.5%) and postpartum hemorrhage (28.3%) were the main reasons for admission of cases. Educational level of women (AOR = 4.80, 95% CI: 1.78–12.90), education level of husbands (AOR = 5.26; 95% CI: 1.46–18.90), being referred from other health facilities (AOR = 4.73, 95% CI: 1.78–12.55), antenatal care visit (AOR = 2.75, 95% CI: 1.13–6.72), cesarean section (AOR = 3.70, 95% CI: 1.42-9.60), and medical disorder during pregnancy (AOR = 12.06, 95% CI: 2.82–51.55) were found to significantly increase the risk of maternal near-miss. Whereas, the younger age of women significantly decreased the risk of maternal near miss (AOR = 0.26, 95% CI: 0.09–0.75).ConclusionAge, educational level, antenatal care follow-ups, medical disorder during pregnancy, mode of admission, and mode of delivery were significant predictors of maternal near-miss. Socio-demographic development, use of ANC services, early detection and management of medical diseases, reducing cesarean section, and improving the referral systems are crucial to minimizing the maternal near-miss.
Efficacy and safety of transarterial chemoembolization with CalliSpheres® Microspheres in head and neck cancer
Authors: Gao Fei , Gao Jinqi , Wang Kuiyang , Song Lei 
Published: August 2022

ObjectiveTransarterial chemoembolization with CalliSpheres® Microspheres (CSM-TACE) presents favorable efficacy and tolerable safety in several cancers, while its application in head and neck cancer (HNC) is unclear. Thus, the current pilot study aims to evaluate the efficacy and safety of CSM-TACE in treating HNC.MethodsA total of 15 HNC patients receiving CSM-TACE at the Second Affiliated Hospital of Dalian Medical University from March 2017 to December 2021 were enrolled in this study. Moreover, treatment information, treatment response, progression-free survival (PFS), overall survival (OS), changes in liver and renal function indices, and adverse events were recorded.ResultsThere were nine patients receiving CSM-TACE as first-line treatment and six patients receiving CSM-TACE as second- or above-line treatment; meanwhile, there were seven, seven, and one patient undergoing one time, two times, and three times of CSM-TACE, respectively. Furthermore, the objective response rate (ORR) and the disease control rate (DCR) were 60.0% and 100%, respectively, at the first month; meanwhile, the ORR and the DCR were 53.3% and 73.3%, respectively, at the second month. Moreover, the 1-year PFS rate was 34.1%, and the 1-year OS rate was 38.9%. Additionally, no change in liver function indices (namely, total protein, albumin, total bilirubin, alanine aminotransferase, and aspartate aminotransferase) or in renal function indices (namely, creatinine and blood urea nitrogen) was found before and 1 month after treatment (all P &gt; 0.05). Meanwhile, no severe adverse events were found during and after CSM-TACE.ConclusionCSM-TACE illustrates favorable treatment response and survival benefits as well as a tolerable safety profile in HNC patients.
Community-Based Malaria Testing Reduces Polypharmacy in a Population-Based Survey of Febrile Illness in Western Kenya
Authors: Laktabai Jeremiah , Platt Alyssa C. , Turner Elizabeth , Saran Indrani , Kipkoech Joseph , Menya Diana , O’Meara Wendy Prudhomme 
Published: August 2022

Objective: The objective was to describe the relationship between the location of care, the malaria test result, and the type of medicine consumed for the fever, and to determine whether community-based access to malaria testing reduced polypharmacy.Methods: This is a secondary analysis of a cluster-randomized trial of an intervention designed to increase diagnostic testing and targeting of Artemesinin Combined Therapies (ACTs). Data collected at baseline, 12, and 18 months were analyzed to determine the impact of diagnostic testing on drug consumption patterns among febrile individuals.Results: Of the 5,756 participants analyzed, 60.1% were female, 42% were aged 5–17 years, and 58.1% sought care for fever in a retail outlet. Consumption of both ACT and antibiotics was 22.1% (n = 443/2008) at baseline. At endline, dual consumption had declined to 16.6%. There was reduced antibiotic consumption among those testing positive for malaria (39.5%–26.5%) and those testing negative (63.4%–55.1%), accompanied by a substantial decline in ACT use among malaria-negative participants.Conclusion: Diagnostic testing for malaria reduces dual consumption of ACTs and antibiotics, especially among those testing outside the formal healthcare sector.
Liver Transplant Recipient Characteristics Associated With Worse Post-Transplant Outcomes in Using Elderly Donors
Authors: Shimada Shingo , Shamaa Tayseer , Ivanics Tommy , Kitajima Toshihiro , Collins Kelly , Rizzari Michael , Yoshida Atsushi , Abouljoud Marwan , Moonka Dilip , Lu Mei , Nagai Shunji 
Published: August 2022

Advanced age of liver donor is a risk factor for graft loss after transplant. We sought to identify recipient characteristics associated with negative post-liver transplant (LT) outcomes in the context of elderly donors. Using 2014–2019 OPTN/UNOS data, LT recipients were classified by donor age: ≥70, 40–69, and &lt;40 years. Recipient risk factors for one-year graft loss were identified and created a risk stratification system and validated it using 2020 OPTN/UNOS data set. At transplant, significant recipient risk factors for one-year graft loss were: previous liver transplant (adjusted hazard ratio [aHR] 4.37, 95%CI 1.98–9.65); mechanical ventilation (aHR 4.28, 95%CI 1.95–9.43); portal thrombus (aHR 1.87, 95%CI 1.26–2.77); serum sodium &lt;125 mEq/L (aHR 2.88, 95%CI 1.34–6.20); and Karnofsky score 10–30% (aHR 2.03, 95%CI 1.13–3.65), 40–60% (aHR 1.65, 95%CI 1.08–2.51). Using those risk factors and multiplying HRs, recipients were divided into low-risk (n = 931) and high-risk (n = 294). Adjusted risk of one-year graft loss in the low-risk recipient group was similar to that of patients with younger donors; results were consistent using validation dataset. Our results show that a system of careful recipient selection can reduce the risks of graft loss associated with older donor age.
Analysis of Sanitizer Rotation on the Susceptibility, Biofilm Forming Ability and Caco-2 Cell Adhesion and Invasion of Listeria
Authors: Rahman Md Asfakur , Sahoo Nirakar , Yemmireddy Veerachandra 
Published: August 2022

The purpose of this study was to determine the effect of sanitizer use conditions on the susceptibility, biofilm forming ability and pathogenicity of Listeria monocytogenes. Two different strains of L. monocytogenes and a non-pathogenic L. innocua were exposed to sodium hypochlorite, benzalkonium chloride and peroxyacetic acid at different concentrations (4 to 512 ppm) and treatment times (30 s to 5 min), respectively. Under the tested conditions, no significant difference (p > 0.05) in reduction was observed among the three tested sanitizers. A reduction of 1 to 8 log CFU/mL was observed depending upon the sanitizer concentration and treatment times. The survived cells at the highest sublethal concentration and treatment time of a particular sanitizer upon re-exposure to the same or different sanitizer showed either no change or increased susceptibility when compared to parent strains. Upon repeated exposure to sanitizers at progressively increasing concentrations from 1 to 128 ppm, L. innocua was able to survive concentrations of up to 32 ppm benzalkonium chloride and 64 ppm peroxyacetic acid treatments, respectively. At the tested sub-lethal concentrations, no significant difference (p > 0.05) in biofilm formation was observed among the tested strains. Caco-2 interaction with L. innocua showed a reduction in invasion ability with sublethal concentrations of sanitizers.
Programa de fortalecimiento familiar en unidades educativas. Un ejercicio de vinculación con la sociedad
Authors: Moreira Chica Tatiana Katiuska , Romero Chávez Sandra Auxiliadora , Montesdeoca Espinoza Mercedes Alexandra 
Published: August 2022

El objetivo de esta investigación fue fortalecer el vínculo familiar de los padres de familia, de los estudiantes y su incidencia en el rendimiento académico, a través del programa impartido por el área de vinculación denominado Fortalecimiento Familiar, que abarca una serie de proyectos ejecutados, por estudiantes de la escuela de Trabajo Social de la Universidad Técnica de Manabí (UTM). Esta iniciativa responde a las demandas sociales y a lo que establece el Plan Nacional del Buen Vivir. La Escuela de Trabajo Social en el año 2015 intervino con un programa de Fortalecimiento Familiar y cinco proyectos. En el proceso de implementación de los proyectos se realizaron 10 sesiones de trabajos con padres de familias y estudiantes de las Unidades Educativas: Portoviejo, Pedro Zambrano Izaguirre, Luis Dueñas Vera, Otto Arosemena Gómez y Aquiles Valencia, de los cantones de Portoviejo y Rocafuerte. La metodología cualitativa se apoyó en talleres que incluían técnicas expositivas, dialogadas, lluvias de ideas y videos. En cada actividad realizada se ejecutaron talleres de concientización e integración, para padres de familia, estudiantes y docentes, incluyendo temas como valores, hábitos de estudio, resilencia, autoestima, crecimiento personal, entre otros.
Webinar como recurso de capacitación formal y no formal, caso: Titulados en Secretariado Ejecutivo
Authors: Morales Intriago Juan Carlos , García Castro Mayra Elizabeth , Arteaga Pita Iván Gasendy 
Published: August 2022

Con el vertiginoso avance tecnológico en las diversas áreas del conocimiento, las formas de comunicación han ido evolucionando en cuanto a medios, canales y soportes, lo que ha permitido la creación de herramientas que optimizan los procesos de formación profesional, sea ésta formal e informal. Los denominados Webinars o Seminarios web evolucionan la forma tradicional de organizar eventos como: talleres, seminarios o conferencias. El trabajo demuestra los beneficios de los procesos de formación ambientados en Webinar, como generador de competencias informacionales y de trabajo cooperativo para el apoyo y transferencia de ciencia y tecnología entre investigadores. La metodología tiene un enfoque cuali-cuantitativo apoyado en el método descriptivo para determinar factores como disponibilidad de recursos, conectividad, accesibilidad, aplicaciones, acompañamiento, entre otros indicadores, de manera que se logró una mirada integral al proceso de formación ambientado en Webinar, tomando como caso de estudio a los profesionales en Secretariado Ejecutivo. Los resultados de la investigación demuestran como los usuarios de ReHuSo. Publicación cuatrimestral. Vol. 1, Año 2016, No. 3 (Septiembre– Diciembre) estos entornos virtuales mejoran significativamente su desempeño individual y colectivo en sus actividades profesionales.
Incidencia de la usabilidad de la intranet en la Pontificia Universidad Católica del Ecuador, sede Manabí
Authors: Ormaza Pincay María De Los Ángeles 
Published: August 2022

La usabilidad estudia la forma de presentar los recursos educativos y de entretenimiento de manera que puedan ser accedidos por todos sus usuarios independientemente del conocimiento que tengan de las tecnologías de la información y comunicación y de la tecnología que estos usuarios dispongan. En la presente investigación se examinaron los antecedentes teóricos y conceptuales de la usabilidad. Se aborda la importancia de la intranet como un espacio para la comunicación en las organizaciones, se exponen sus características y se presenta la problemática relacionada con la calidad. Se describen algunos de los principales métodos de evaluación de la usabilidad y se diseña el instrumento para evaluar la intranet de la Pontificia Universidad Católica del Ecuador, sede Manabí; donde se analizan los niveles de usabilidad de la misma, aplicando el instrumento elaborado. Se evidenció buena aceptación de la intranet, los usuarios se mostraron satisfechos en cuanto al diseño gráfico, los contenidos ofrecidos y la variedad de los servicios.
Corpo e violência na construção das intersubjetividades juvenis no ensino médio: lutas por reconhecimento
Authors: Link Elmer Erico , Silva Jeferson da , Ratto Cleber Gibbon 
Published: August 2022

Busca-se neste ensaio, apresentar de forma sucinta os primeiros passos de um projeto de tese de doutorado, na intenção de entender a construção da intersubjetividade juvenil e luta por reconhecimento no corpo, na integração pessoal no contexto escolar do ensino médio. A partir do fenômeno intersubjetivo que os jovens apresentam no ambiente escolar, na tensão potente, dos estereótipos de jovens violentos e apáticos, que dão indícios de patologias sociais na contemporaneidade. Essa transição tem causado uma crise nas formas de viver, de educar e nas instituições tradicionais. No intuito de compreender o jovem e seu discurso contemporâneo marcado pelos sintomas da cultura, fundamentar-se-á na Teoria de Luta por reconhecimento de Axel Honneth e na teoria psicanalítica do Amadurecimento pessoal de Donald Winnicott, uma pesquisa investigativa, exploratória e descritiva. A partir dos dados que serão coletados junto aos jovens do Ensino Médio, através de grupo de discussão, numa fusão de horizontes na perspectiva fenomenológica-hermenêutica em Hans-Georg Gadamer que permita compreender o fenômeno social.
Lessons Learned process case study: An unintended enabler of upstream and downstream knowledge management capabilities at the European Space Agency
Authors: Herd Andrew , Piretti Francesca 
Published: August 2022

The paper presents a case study of the European Space Agency which has been coordinating internal knowledge management activities at the corporate level of the Agency for just over 6 years. In this time, previous, current, and future knowledge management activities have been respectively collected, supported, and planned with the immediate intent of addressing potential knowledge loss due to an on-going retirement wave – which will last until 2030. One of the ranges of knowledge management techniques applied is the lessons learned process, with associated means and tools being realised for the capture and exchange of experience.
Through the focus on using the validated and evaluated lessons to achieve systematic learning, the lessons learned process has achieved learning at the point of use, rather than mostly keeping the learning within the established Lessons Learned tool, which has also had (unintentionally) caused an enabling effect for other organisational capabilities relating to not only knowledge but also information and data management.
The Agency has then made a relatively rapid transition to adopting a systematic approach to Lessons Learned – by both creating the need for (pre-requisite) upstream and “downstream” capabilities. The downstream benefits (learning flowing out of the experience capture) has been achieved by identifying the process, product and people involved in the desired learning outcome, and assuring the learning is placed at this point. In taking the approach of broadening the reach of a traditional lessons learned process (mostly with the aim of more effectively addressing user needs), the establishment of lessons learned capabilities has also enabled the needed upstream development activities for the deployment of lessons learned itself. Aspects such as a solid IT infrastructure (common platform), a robust set of classification terms (taxonomy), and the existence of users with a clear identity (communities of practice).
The paper will present the current (but rapidly progressing) status of lessons learned at ESA, and the upstream and downstream effects from the perspective of lessons learned as part of an overall organisational strategy to create a culture and climate of openness and sharing (knowledge management) and digitalisation (information and data management).
The Dynamics of Power and Micropolitics on Project Management
Authors: Olaisen Johan , Jevnaker Birgit Helene 
Published: August 2022

The empirically investigated problem of our paper is what impact do micropolitics and power have upon the conduct of project management in an organization? The informal power and micropolitics played a massive role in the projects, and personal and relational knowledge appeared in all projects to achieve the expected results. The project manager uses personal networks, personal relations, and mentor's network together with cognitive, affective, and emotional influence as power and politics if needed to achieve expected results. Power and micropolitics were necessary skills and tools for a successful project manager. The findings relate to the manager's intentions. The informal power and micro-politics process are reused in every project because informal power and micropolitics are a part of project work. Power accumulation and wise handling are essential leadership tools for every manager. Employees work for managers who have power over those who do not. The former can get them what they want: visibility, upwards mobility, and resources. Micropolitics and power represent a unique competence (i.e., knowledge, experiences, and attitudes) and tool for handling any project. A democratic and consensus-oriented decision process opens for power games and micropolitics rather than hedging them in more hierarchical organizations. A complex matrix organization involving employees in many projects is also open to micropolitics and power. Micropolitics and power might prolong and complicate decisions processes in ordinary projects and improve processes in fast-track projects. Micropolitics and power might thus both increase and reduce the effectiveness and efficiency of an organization.
Facilitating Cyber Security Threat Modelling: A Social Capital Perspective
Authors: Orjatsalo Johanna 
Published: August 2022

To identify and manage their cyber security risks, organisations need to form a thorough understanding of various factors that may expose them to these risks. While cyber security professionals and scholars have developed a plethora of practical methodologies and frameworks to support cyber security risk identification and mitigation, the theoretical foundations on what promotes effective knowledge creation when using these methodologies and frameworks are nascent. Yet, theories developed in the field of knowledge management and intellectual capital may provide valuable insight on how to enhance cyber security risk related knowledge creation in organisations. For example, social capital is considered as an important prerequisite for knowledge exchange and combination when creating new intellectual capital (Nahapiet & Ghoshal, 1998). However, more focused research is required to understand how social capital affects knowledge creation in the context of organisational cyber security risk related activities.

Using qualitative data gathered from three cyber security threat modelling workshops, this paper examines how social capital enables conditions for exchanging and combining knowledge on cyber security threats. By comparing the empirical observations with Nahapiet and Ghoshal’s (1998) model, this study identifies practical approaches that are used by threat modelling workshop facilitators to create conditions for effective knowledge exchange and combination. This study provides both cyber security scholars and professionals with an example on how to use knowledge creation related academic theories to analyse and further enhance cyber security risk management approaches by creating a connection between Nahapiet and Ghoshal’s (1998) social capital model and cyber security threat modelling.