bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reduced Precision Redundancy Systems by Approximation (RPA)
Authors: Junsangsri Salin , Lombardi Fabrizio 
Published: October 2022

<p>This paper proposes new designs for Reduced Precision Redundancy (RPR) systems using Approximation (RPAs). Reduced redundancy is accomplished by utilizing approximate modules, hence requiring substantially different designs for the decision hardware for generating an output. Some of proposed schemes deal with a single erroneous data word generated by a module (in the presence of single and multiple bit errors) using three modules as inputs to the decision hardware of the RPA (denoted as 2E1A and 1E2A where E (A) stands for exact (approximate)). The remaining RPA schemes operate under single and multiple bit errors in at most two modules out of four input modules (denoted as 2E2A). Different from RPRs found in the technical literature, the proposed RPAs operate using only logic operations (so no arithmetic unit is involved as decision hardware). The probability of providing an exact data word at the output of the RPA under the above error conditions is analytically found; simulation results are also provided. It is shown that the difference between simulated and analytical probabilities is at most 5%. Circuit based metrics (such as delay, power dissipation, and area) of the proposed designs are simulated and compared with RPR; the proposed designs outperform RPR in all metrics, except the area of the four-input RPA (2E2A) due to the larger number of modules. The application of the proposed RPAs to image processing is also presented; the results show that the proposed schemes are very efficient for such application. </p>
Peran Penting Komunikasi Pada Era Globalisasi
Authors: Sukarni Sukarni 
Published: October 2022

Komunikasi pada era globalisasi sekarang ini mengalami kemajuan yang sangat pesat, baik komunikasi satu arah maupun dua arah, langsung maupun tidak langsung. Hal tersebut sesuai dengan kebutuhan informasi yang semakin berkembang pula. Kebutuhan terhadap informasi merupakan kebutuhan semua orang termasuk para siswa. Penelitian ini merupakan Penelitiaan Tindakan Kelas (PTK) yang dilakukan oleh guru di dalam kelasnya. Proses pembelajaran dengan menggunakan model pembelajaran kooperatif tipe Jigsaw untuk meningkatkan kompetensi menelaah ejaan surat dinas pada siswa kelas VII B SMP Negeri 1 Cilacap tahun pelajaran 2016/2017 dilakukan dengan membagi siswa dalam kelompok ahli dan kelompok asal. Kelompok ahli membahas penggunaan ejaan sedangkan kelompok asal menelaah ejaan surat dinas. Hasil diskusi dalam kelompok ahli disampaikan dalam kelompok asal, sebagai dasar mengerjakan tugas menelaah ejaan, baik tugas kelompok maupun mandiri.
Treatment Patterns of Follicular Lymphoma in the United States: A Claims Analysis
Authors: Huntington Scott F. , Appukkuttan Sreevalsa , Wang Wenyi , Du Yuxian , Hopson Sari , Babajanyan Svetlana 
Published: October 2022

Background: A consensus is lacking on optimal treatment sequencing for follicular lymphoma (FL), the most common indolent lymphoma. FL is incurable, and many patients require multiple lines of therapy for successive relapses. Guidelines provide numerous recommendations for first-, second-, and third-line therapy; however, treatment patterns in the real world remain poorly understood. Objectives: The primary objective of this study is to evaluate real-world treatment patterns among commercially insured patients with FL in the United States. Methods: A retrospective cohort of patients with newly diagnosed FL was identified from June 2008 to September 2016 using the IBM MarketScan® database. Treatment pattern measures, including time to treatment from diagnosis, days from previous line of therapy, duration of therapy, and distribution of treatment regimens among lines of therapy, were assessed. Descriptive statistics were reported for baseline characteristics, primary outcome, and treatment pattern measures. Results: In total, 4232 patients were identified from the database and 2111 patients received at least 1 line of treatment. The most common first-line treatments included bendamustine + rituximab (39%), rituximab + cyclophosphamide + doxorubicin + vincristine (20%), and rituximab monotherapy (19%). Rituximab monotherapy was the most common second-line (34%) and third or greater line (57%) treatment. The median time from FL diagnosis to initiation of treatment was 50 days (interquartile range [IQR]: 28-191) for first-line treatment, 577 days (IQR: 312-1146) for second-line, and 776 days (IQR: 603-1290) for third-line. Discussion: At a median follow-up of 3.6 years, most patients had 1 or fewer lines of therapy. The use of combination therapy decreased with each line of therapy and the numbers of patients receiving third- or fourth-line therapy were small in this study, potentially due to the short follow-up. Rituximab as monotherapy or in combination was utilized most frequently; however, the variety of other therapies used demonstrates that the standard management of FL remains unclear. Conclusions: Consensus on optimal treatment sequencing is currently lacking, and patients receive a variety of active regimens during routine practice. In this contemporary cohort of patients diagnosed with FL in the United States, rituximab therapy predominated both in monotherapy and in combination.
Approximations of the Mittag-Leffler operator function with exponential accuracy and their application to solving of evolution equations with fractional derivative in time
Authors: Gavrilyuk I. P. , Makarov V. L. 
Published: October 2022

УДК 519.62
Запропоновано та проаналізовано ефективну дискретизацію операторної функції Міттаг-Леффлера

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Anesthesia management and challenges during interventional pulmonology procedures for central airway obstructions
Authors: ÜLGER Gülay , SAZAK Hilal , UZEL ŞENER Melahat , ÖZTÜRK Ayperi , ZENGİN Musa , ALAGÖZ Ali 
Published: October 2022

Aim: Central airway obstructions (CAO) are one of the main reasons for morbidity and mortality, often originate in the lungs, and are generally unresectable. Interventional airway procedure is a preferred method in these cases. This study aimed to analyze anesthesia management in patients undergoing interventional procedures for CAO. We aimed to highlight the problem and solutions that may be encountered in such cases.
Material and Method: The data of 49 patients who had interventional airway procedure were analyzed retrospectively. Patients’ demographic data, type of interventional procedures, localization of the lesion, and duration of the procedure were analyzed. Vital parameters and arterial blood gases (ABG) levels had been recorded before anesthesia induction (T1), after rigid bronchoscope insertion (T2), 20th-minute of the procedure (T3), after extubation (T4), and in the postoperative care unit (T5).
Results: The mean age was 57.90±11.99 years. The mean duration of the procedure was 34.75±15.62 minutes. The majority of the patients had American Society of Anesthesiologists (ASA) III-IV physical status. CAOs were mostly found in the main bronchus. Tumors debulking, biopsy, mechanical dilatation, argon plasma coagulation, and mechanical tumor resection were the most performed procedures. Stent insertion was performed in 3 (6.1%) patients. Two patients (4.1%) had bleeding, 3 (6.1%) patients had desaturation, and 1 (2.1%) patient had atrial fibrillation.
Conclusion: Interventional airway procedures are frequently used for high risk patients with CAO and comorbidities. Detailed preoperative evaluation, periprocedural teamwork, and close hemodynamic and ABG follow-up are keys to success.
Hypothermia: what are the trends in recent studies? – a bibliometric analysis with global productivity
Authors: ZENGİN Emine Nilgün 
Published: October 2022

Aim: Although the number of global studies on hypothermia, which plays an important role in morbidity and mortality in adults and newborns, has increased, there is still no bibliometric research on this subject in the literature. This study, it was aimed to determine trend topics and global productivity by using various statistical analyzes of scientific articles published on hypothermia.
Material and Method: Articles on hypothermia published between 1980 and 2021 were downloaded from the Web of Science (WoS) database and analyzed using various statistical and bibliometric methods. Spearman’s correlation coefficient was used for correlation studies. Network visualization maps were used to identify effective studies, global collaborations, and trend topics with citation analyses.
Results: Out of a total of 14410 publications, 8157 articles were analyzed. The top 5 contributors to the literature are USA (n=2938, 36%), Japan (737, 9%), UK (641, 7.8%), Germany (576, 7%), and China (544, 6%). was. The first 3 journals that published the most articles were Resuscitation (n=296), Critical Care Medicine (146), Therapeutic Hypothermia, and Temperature Management (135). The top 3 most active institutions were League of European Research Universities (n=448), University of California System (274), and Pennsylvania Commonwealth System of Higher Education (221). The most active author was Marianne Thoresen (n=69).
Conclusion: The most studied trend topics in recent years are determined as hypoxic-ischemic encephalopathy, neonatal encephalopathy, out-of-hospital cardiac arrest, neonates, targeted management, therapeutic hypothermia, extracorporeal membrane oxygenation, perioperative hypothermia, emergency medicine, outcome, mortality, and perinatal asphyxia. This study will guide the authors who want to study in this area.
Prognostic factors between the proximal femoral nail and bipolar hemiarthroplasty in femoral intertrochanteric fractures
Authors: AYGÜN Ümit , AYIK Ömer 
Published: October 2022

Aim: In the treatment of intertrochanteric femur fractures, proximal femoral nail (PFN), and bipolar hemiarthroplasty (BPH) are widely used. This study aimed to compare these two types of implants depending on risk factors regarding patients.
Material and Method: PFN (Group 1) was applied to 40 of the 89 patients (44 female, 45 male) aged between 51-80 (mean 68.16±6.78) and BPH (Group 2) was applied to 49 of them. Age, gender, fracture side, fracture mechanism, additional disease, Body mass index (BMI), Albumin level, Hemoglobin (Hb) decrease level, T-score, American Society of Anesthesiologists (ASA) classification, type of anesthesia, surgery type, operation time, hospital stay and full weight-bearing time, Harris Hip Score (HHS) in preoperative and postoperative periods, classification of intertrochanter fracture according to the AO Foundation and Orthopedic Trauma Association (AO/OTA), postoperative complications were recorded.
Results: Group 1 was younger with a mean age of 64.55±6.23 years compared to Group 2 (p 0.05). In group 1, operation time was 46.78±5.29 minutes and hospital stay was 2.48±0.75 days, which was shorter, most surgery types were closed, T-score was -2.49±0.59 and better, the time of full weight-bearing was 3.48±0.78 months, Hb decrease was 1.17±0.37 g/dL and less, Albumin level was 3.11±0.4 g/dL and higher (p
Comparision of the scoring systems to predict clinical outcomes in older adults with biliary pancreatitis: a cross-sectional study
Authors: İNAN Osman , ACEHAN Muhammed Fatih , ŞAHİNER Enes Seyda , ASLAN Meryem , ALTIPARMAK Emin , ATEŞ İhsan 
Published: October 2022

Aim: The issue of which scoring system is appropriate in older adults patients with acute biliary pancreatitis is an ongoing debate. We aimed to compare the efficiency of four existing scoring systems in predicting clinical outcomes in the elderly with acute biliary pancreatitis.
Material and Method: The study included patients aged 60 years and older with a diagnosis of acute biliary pancreatitis. Clinical findings, routine laboratory examinations, and imaging findings were retrospectively accessed through the hospital information system and reviewed. Then, the efficacy of Ranson, Bedside Index of Severity in Acute Pancreatitis (BISAP), Glasgow-Imrie, and Acute Physiology and Chronic Health Evaluation (APACHE) II scoring systems in predicting mortality, severity, organ failure, complications, intensive care unit (ICU) admission, and prolonged hospital stay (PHS) were compared.
Results: The Ranson score was compared with three other existing scoring systems in primary and secondary outcomes in 364 eligible patients. The area under the curve (AUC) values of the Ranson, BISAP, Glasgow, and APACHE II scores were 0.787 (95% CI: 0.649-0.925), 0.856 (95% CI: 0.784-0.929), 0.908 (95% CI: 0.854-0.961), and 0.836 (95% CI: 0.702-0.971) for mortality. Although the AUC of the Ranson score for mortality was lower than that of the other scores, no significant difference was found in pairwise comparisons with the other three scores (p>0.05 for all).
Conclusion: The Ranson scoring system was the weakest among the assessed scoring systems in predicting clinical outcomes in older adults with biliary pancreatitis.
The effect of body satisfaction on female sexual life after bariatric surgery: a follow-up study
Authors: ŞAHİN CAN Merve , ÇAY Ferhat 
Published: October 2022

Aim: Discomfort with body shape is common among individuals with obesity and has effects on their sexual life. We aimed to investigate the effects of bariatric surgery on the body satisfaction and sexual life of women in this study.
Material and Method: The study consisted of 63 female patients who were aged between 20 and 55. Pre-operative psychiatric evaluations of the candidates were conducted and Hamilton Anxiety Scale , Hamilton Depression Scale, Arizona Sexual Experiences Questionnaire and Body Shape Questionnaire were used. Psychiatric evaluations of the patients were re-evaluated in the first year after surgery.
Results: The mean age was 35.4±8.6 years. While 87.3% of the participants had moderate-severe anxiety about the appearance of their bodies before the operation, 57.1% described problems in their sexual life. After the operation, 63.5% of the participants stated that they did not have any concerns about their body appearance, and 73% stated that they did not have any problems in their sexual life. The BSQ-34 scale score was found to be higher in those with an Arizona score of 11 and above before the operation (p=0.045; p
Correlation of the transcutaneous bilirubin and serum bilirubin levels measured before and after phototherapy in newborns: a prospective observational study
Authors: EKMEN Sadrettin , DENİZ Yusuf 
Published: October 2022

Aim: The purpose of the present study was to show the reliability of the transcutaneous bilirubin (TcB) measurement as an alternative method to total serum bilirubin (TSB) when starting treatment with phototherapy (PT), which is one of the most important treatment methods of hyperbilirubinemia as a very common practice in the neonatal period and eliminates the disadvantages of blood collection.
Materyal and Method: Two measurements were made to evaluate whether there was a correlation between the total serum bilirubin and transcutaneous bilirubin level measurement for follow-up in newborns who were hospitalized and prospectively followed up in the Newborn Intensive Care Unit of Karabuk University Medical Faculty Training and Research Hospital between April 13 and June 30, 2022 (Level III Neonatal Center) who were scheduled for starting phototherapy. The primary result was the correlation between TcB and TSB at the first 24 hours and after, at the initiation of FT, termination of FT, and 12 hours after PT was discontinued.
Results: The TSB and TcB values of the newborns ​​were measured at the beginning of PT, at the end of PT, and 12 hours after PT was ended. The first measurement values ​​were 11.60±5.16 and 10.72±4.02, respectively; the second measurement values ​​were 7.45±2.34 and 6.35±2.83, respectively; and the third measurement values ​​were 8.03±2.45 and 7.35±2.63 mg/dL, respectively. A strong positive correlation was found among all measurement values. Also, when the newborns who received FT for the first 24 hours were evaluated by subgrouping, the high correlation between TcB and TSB levels continued.
Conclusion: The present study showed that there is a significant relationship between TcB taken from the covered skin and TSB at the start, end, and 12 hours after PT. Also, when the newborns who received PT for the first 24 hours were evaluated in a subgroup, it was found that TCB measurement predicted the TSB level at a high level before and after PT. Based on these findings, it was concluded that TcB measurement, including in the first 24 hours, is reliable in the follow-up of newborns receiving PT for the treatment of hyperbilirubinemia. However, we think that larger prospective controlled studies are required in this respect.
Erythromycin resistance in Group A Beta-hemolytic streptococci
Authors: BALCI Pervin 
Published: October 2022

Aim: Streptococcus pyogenes (Group A Beta-hemolytic streptococci, GABHS) is one of the important bacterial pathogens in clinical microbiology. It often causes upper respiratory tract infections such as tonsillitis, pharyngitis, and laryngitis. It also leads to complications such as acute rheumatic fever and post-streptococcal glomerulonephritis. Early diagnosis and treatment of these bacterial infections will prevent suppurative and non-suppurative complications, the transmission of infection to other people, and chronic carriage. Today, the treatment of streptococcal infections relies entirely on chemotherapy. Beta hemolytic group A streptococci and generally other beta-hemolytic streptococci in groups B (GBBHS), C, and G are generally sensitive to many chemotherapeutics, especially Penicillin and Erythromycin. In patients with penicillin allergy, erythromycin, amoxicillin-clavulanate, or oral cephalosporins are used instead of penicillin. However, it has recently been understood that there are strains resistant to Erythromycin in GABHS and are increasing. In this study, the situation in our region of Erythromycin resistance, which is used as an alternative for people allergic to Penicillin in the treatment of streptococcal infections, was investigated.
Material and Method: In our study, throat swab samples were taken from 150 pharyngitis patients and 94 GABHS were obtained by applying the Bacitracin-SXT test with the culture method, and antibiotic susceptibility tests were performed on these 94 GABHS by Kirby-Bauer agar disc diffusion method.
Result: GABHS was found susceptible to Bacitracin and resistant to SXT. GBBHS is resistant to Bacitracin and SXT. other beta-hemolytic streptococci were resistant to Bacitracin and susceptible to SXT.
Conclusion: In this study, Erythromycin’s resistance was found to be 19.1%. it is observed that Erythromycin resistance has increased over the years when compared to previous studies. Erythromycin should not be used empirically in treatment. An antibiotic susceptibility test should be performed and the antibiotic should be selected according to the results of the antibiogram test.
The effect of COVID-19 infection on anti mullerian hormone
Authors: AYAR MADENLİ Asena , GÜRKAN Naziye , ALANYA TOSUN Şebnem 
Published: October 2022

Aim: The possible impact of COVID-19 infection on female reproductive system is a controversial issue. The aim of this study was to investigate the effect of COVID-19 infection on anti mullerian hormone (AMH) as a predictor of ovarian response to ovarian stimulation.
Material and Method: This prospective study was conducted at a university-affiliated tertiary medical center between June 2021–February 2022. The study population included 79 reproductive-aged women (22-34 years) with COVID-19 infection. Blood samples were collected for AMH levels before COVID-19 infection and after three months of COVID-19 disease.
Results: The mean age of the study group was 28.11±3.49 years. Estradiol and Luteinizing Hormone (LH) was found to be lower after three months of COVID-19 disease (p
Evaluation of effect of nilotinib in an experimental corneal neovascularization model
Authors: YILDIRIM Hakan , BALBABA Mehmet , ERDAĞ Murat , CANLEBLEBİCİ Mehmet , DAL Ali , İLHAN Nevin , ERÖKSÜZ Yesari , GÜNGÖR KOBAT Sabiha 
Published: October 2022

Aim: This study aims to investigate the neovascularization-inhibiting effect of topical nilotinib and to determine the effective dose of nilotinib.
Material and Method: In this study, 42 healthy Wistar albino rats were randomly divided into six groups. The left corneas of all rats except group 1 were cauterized with silver nitrate. Group 1 was the healthy control, with no corneal vascularization, which did not receive any treatment; Group 2 (sham) did not receive treatment, only topical DMSO; Groups 3, 4, and 5 received topical nilotinib at doses of 10, 20, and 40 μM three times a day, respectively; Group 6 received 5 mg/dL topical bevacizumab three times for a day for seven days. On the 8th day, photographs of the corneas were taken, and the percentage of corneal neovascularization area was calculated. Following all rats being killed via anesthesia, the corneas were removed to determine the levels of vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) ELISA and corneal immune staining.
Results: Other than Group 3, the percentage of neovascular corneal area was lower in the treatment groups compared to Group 2 (p
Our experience with percutaneous endoscopic gastrostomy and long-term follow-up results
Authors: DURAK Serdar , FİDAN Sami , ERKUT Murat , COŞAR Arif Mansur 
Published: October 2022

Aim: Percutaneous endoscopic gastrostomy (PEG) is the preferred method for long-term enteral feeding of patients who cannot be fed orally for various reasons and have a functioning gastrointestinal system. In this study, we aimed to present and discuss the demographic characteristics, indications, and early and late complications of patients implanted with the endoscopic PEG in our center.
Material and Method: In this study, we retrospectively evaluated age, gender, chronic diseases, indication for PEG, complications during the procedure, complications arising from PEG during patient follow-up, and survival times of 84 patients who underwent PEG between January 2016 and January 2020 from the electronic medical file system.
Results: Of the 84 patients enrolled in the study, 59.5% (n=50) were male and 40.5% (n=34) were female. The mean age of the patients was 61.35±19.52 years. The endoscopic PEG success rate was 97.6%. Of the requests for PEG, 58.6% (n=50) were for patients in intensive care units. The most common indications for PEG insertion were cerebrovascular accident (CVA), chronic nervous system disease, and hypoxic-ischemic encephalopathy. Complications related to PEG were observed in 11 patients. All complications were mild, and no severe complications were observed. While one of the complications developed in the early period ( 30 days). No deaths from causes related to the PEG procedure have been observed.
Conclusion: In patients with inadequate oral intake, PEG is a safe and appropriate option for continuous enteral feeding because of its low complication and mortality rates.