bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percutaneous pericardial catheter drainage for symptomatic uremic pericardial effusions with narrow safety margins
Authors: Kim Soon Bae , Yang Eun Hye , Shin Ji Hoon 
Published: October 2022

Background
Percutaneous pericardial catheter drainage (PCD) for pericardial effusion is generally known to be limited by the high risk associated with effusions that are less than 10 mm thick. The objective was to report cases who underwent percutaneous PCD for symptomatic uremic pericardial effusions, which were less than 10 mm thick after cardiologist declined to perform the PCDs because of the narrow safety margins.

Materials and methods
Thirteen consecutive cases (11 patients) (median age, 56 years, range, 31–83) with symptomatic uremic pericardial effusion (thickness <10 mm) affecting the pericardial space anterior to the right ventricle underwent ultrasound- and fluoroscopy-guided percutaneous PCD between September 2015 and April 2022. Information regarding the clinical criteria, echocardiographic features, PCD details, nature of effusion, and outcomes, including success and complications were retrospectively evaluated.

Results
Pigtail catheter (8.5-Fr) insertion was successful for all patients, with a median procedure time of 7 minutes (range 4~12) without procedure-related complications. The median amount of drainage on the day of PCD was 700 mL (range, 250–1100). The median duration of catheter indwelling was 5 days (range, 1~32). In one case, the catheter was removed after 1 day due to chest pain. For all patients, pericardial effusion evacuation was achieved with relief of associated symptoms, representing 100% clinical success.

Conclusion
Percutaneous PCD may be safely performed for patients with symptomatic uremic pericardial effusions and narrow safety margins of less than 10 mm.
Optic Chiasmal Fungal Granuloma - Rare Cause of Blindness
Authors: Saket Saurabh  , Nimesh Jain  , Hrushikesh Kharosekar  , Vernon Velho  
Published: October 2022

Intracranial fungal infections are rare. Their presentation is mostly subtle, clinically atypical in presentation, and they are usually mistaken for tuberculosis or brain tumour. Aspergillosis is the most common cause of intracranial fungal infections. Fungal infection enters the brain directly from the paranasal sinuses, ear, skull bone, or haematogenous spread from the lungs and gastrointestinal tract, or direct inoculation during surgery or trauma. The pathology depends on the route of spread, host immunity, and type of fungus. Intracranially, fungal infection invades brain matter or blood vessels. [1]
The rarity of brain fungal infection, with nonspecific clinical picture, and progression to a fatal outcome provides considerable challenges for both diagnosis and management. Invasive sino-orbital fungal infections are rarely reported in immunocompetent patients in literature. We could not find anything related to primary fungal granuloma of the optic tract reported in literature. We report a case of primary fungal granuloma of optic chiasm in an immunocompetent patient.[2]
13-year-old female patient presented to us with sudden onset of loss of vision in both eyes. There were no other complaints. On neurological examination, there was no vision in both eyes (no perception of light). On fundoscopy, there was bilateral optic atrophy. Rest of the neurological examination was normal. Patient was investigated for magnetic resonance imaging (MRI) of brain with contrast study. MRI of brain was suggestive of a 2.2 x 1.8 x 1.6 cm mass in suprasellar region with its epicentre in the optic chiasma and extending to both optic nerves and optic tract. The lesion was separate from the underlying pituitary gland. The lesion was iso-intense on T1 weighted images and hyper-intense on T2 weighted images. It showed homogenous post-contrast enhancement. Our primary differential diagnosis was optic nerve glioma.
Patient underwent immediate surgery, right peritoneal craniotomy, for excision of lesion. Intra-operatively, a firm yellowish white colored lesion arising from the optic chiasm was seen. Safe subtotal excision was done. Post-operative, there was no improvement in vision.
KADAR ANTIOKSIDAN DAN UJI KESUKAAN TERHADAP MINUMAN KOMBINASI DAUN KELOR DAN BUAH KURMA UNTUK MENINGKATKAN PERFORMA ATLET
Authors: Violeta Dyan , Mardiana Mardiana 
Published: October 2022

Latar belakang: Sumber potensial terbentuknya stress oksidatif adalah olahraga yang memiliki latihan dengan intensitas tinggi yang akan mengakibatkan adanya ketidakseimbangan prooksidan dan antioksidan dalam tubuh atlet yang berisiko pada penurunan performa atlet. Tujuan: penelitian bertujuan untuk mengembangkan formulasi minuman daun kombinasi daun kelor dan buah kurma terhadap kadar antioksidan dan penerimaan uji kesukaan oleh atlet sepak bolaMetode: penelitian ini merupakan penelitian kuantitatif, dengan 3 kali perlakuan yaitu Formula 1 (75 g daun kelor dan 10g buah kurma), Formula 2 (100g daun kelor dan 10g buah kurma) serta Formula 3 (125g daun kelor dan 10g buah kurma) dan 2 kali pengulangan. penilaian kandungan antioksidan menggunakan metode DPPH, serta uji kesukaan dengan panelis tidak terlatih sebanyak 25 orang. pengolahan data menggunakan analisis data kruskall walls dan dilanjutkan dengan uji mann whitney jika diketahui hasil uji kruskall walls menunjukkan terdapat pengaruh nyata.Hasil: Hasil penelitian menunjukkan bahwa formula dengan kadar antioksidan tertinggi adalah formula 3 (125g daun kelor dan 10g buah kurma) ) menghasilkan kadar antioksidan yaitu 26 ppm termasuk kedalam kategori sangat kuat, hasil menunjukkan tidak ada perbedaan signifikan (p=0,952) antar variasi formula minuman kombinasi daun kelor dan buah kurma dan uji organoleptik yang paling dominan disukai pada masing perlakuan adalah Formula 3 (75 g daun kelor dan 10g buah kurma) dengan warna coklat terang, aroma tidak terlalu langu dan tidak menyengat, tekstur cair dan rasa yang tidak pahit.Simpulan: Kombinasi formula daun kelor dan buah kurma dengan kadar antioksidan tertinggi yaitu formula 3 dengan 125gram daun kelor dan 10gram buah kurma menghasilkan nilai 26ppm. Sedangkan uji kesukaan didominasi oleh Formula 1 (75gram daun kelor dan 10gram kurma) dengan warna coklat muda, tidak terlalu menyengat, tekstur cair dan tidak pahir rasanya.Kata Kunci: Antioksidan; Buah kurma; Daun kelor; Uji kesukaan
SOSIO EKONOMI ORANG TUA, UANG SAKU, DAN MEDIA SOSIAL BERHUBUNGAN DENGAN PERILAKU KONSUMSI FAST FOOD PADA REMAJA PUTRI DI KOTA KUPANG
Authors: Zogara Asweros Umbu , Loaloka Meirina Sulastri , Pantaleon Maria Goreti 
Published: October 2022

Latar Belakang: Konsumsi makanan yang kurang sehat, contohnya fast food, akan mempengaruhi kesehatan remaja putri. Fast food mengandung kalori, lemak, protein, gula dan garam yang relatif tinggi dan rendah serat. Jika fast food dikonsumsi secara berlebihan dapat mengakibatkan masalah gizi lebih dan penyakit degeneratif di masa mendatangTujuan: Penelitian ini dilakukan untuk menganalisis hubungan antara sosio ekonomi orang tua, uang saku dan media sosial dengan konsumsi fast food pada remaja putri di Kota Kupang.Metode: Penelitian ini menggunakan desain cross sectional yang dilakukan pada bulan Januari sampai Mei 2022 di Kota Kupang. Sampel penelitian adalah remaja putri di Kota Kupang sebanyak 349 orang yang dipilih dengan teknik accidental sampling. Variabel bebas yaitu sosio ekonomi orang tua, uang saku dan penggunaan media sosial, sedangkan variabel terikat yaitu konsumsi fast food. Uji statistik yang digunakan yaitu uji chi square (p-value <0,05) dan dilanjutkan dengan uji multivariat menggunakan uji regresi logistik (p-value <0.05). Hasil: Sebanyak 58,2% remaja putri mengkonsumsi fast food >3x seminggu. Faktor-faktor yang berhubungan dengan konsumsi fast food pada remaja putri adalah pendidikan ayah (p value<0,001; OR=3,587), pendidikan ibu (p value<0,001; OR=3,069), uang saku (p value=0,035; OR=1,660) dan media sosial (p value=0,011; OR=1,857)Simpulan: Pendidikan orang tua, uang saku dan media sosial berhubungan dengan konsumsi fast food pada remaja putri. Orang tua memiliki peran penting dalam mengontrol konsumsi fast food dengan cara mengatur jumlah uang saku remaja dan dapat menyiapkan lebih banyak makanan sehat di rumah sehingga remaja tidak sering membeli fast food.Kata kunci: Fast food; Media sosial; Sosio ekonomi; Uang saku,
“Writing-to-learn”: the influence of task repetition on CSL writers’ attention to form
Authors: Cui Yachong , Luo Shaoqian 
Published: October 2022

Abstract
The “writing-to-learn” dimension of the second language (L2) writing has generated theoretical and empirical intrigue in the past decade. Task repetition is one variable of interest; however, little attention has been given to its role in individuals’ writing processes. This study explores the influence of task repetition on L2 Chinese learners’ attention to form by analyzing their writing processes. Four advanced learners of Chinese as a second language (CSL) were asked to complete one writing task twice in 10 days under think-aloud conditions. Language-related episodes (LREs), the representation of writers’ attention to form, in participant-produced think-aloud protocols were analyzed along three dimensions: language-related problems, problem-solving strategies, and depth of processing. Results indicated that task repetition in individual writing contributed to learners’ Chinese acquisition, as learners 1) attended closely to the typological characteristics and new/complex forms of Chinese; 2) strove for precise language expression; and 3) were granted time to access external resources and expand their linguistic repertoire. Implications related to task repetition in L2 writing, L2 Chinese instruction, and associated research are discussed.
Cube test applied to the study of orthogonal projections: spatial development promoted by Qubism 3D Modeling
Authors: Chivai Cacilda , Soares A.A. , Catarino P. 
Published: October 2022

AbstractEducation benefits from the globalization of effective tools that facilitate student learning. Education in Mozambique is still traditional without any technological resources, such as computers, data show, applied software and smartphones. This traditional model drives some difficulties in 3D perception in technical drawing (TD) subjects. Technological tools with 3D visualization allow the enhancement of the learning process in an interactive and innovative way, giving the teacher the power to select the most appropriate technological resource for the desired subject. Qubism 3D modeling (Q3DM) and the cube test (CT) are the technological resources selected for this study, as they present usability features capable of promoting 3D spatial skills in the study of orthogonal projections (OP). The research was conducted in a secondary school in southern Mozambique, it is a quasi-experimental case study, supported by a mixed quantitative and qualitative approach. The instruments used were a pre-test and a post-test applied to two groups of students; one experimental and one control. Fifty students solved practical exercises on OP and their level of spatial visualization was measured with the CT. The study aims to investigate whether the use of Q3DM as a teaching-learning tool promotes 3D spatial visualization of objects in the context of technical drawing. From the analysis of the CT results it is inferred that the students who used Q3DM had better results on the cube test.
Fractal dimension of wood pores from pore size distribution
Authors: Tibebu Dessie T. , Avramidis Stavros 
Published: October 2022

Abstract
Understanding wood pore geometry and distribution is the basis for studying its macroscopic properties. This research investigated the pore fractal dimension using the pore size distribution of selected softwoods and hardwoods. Mercury intrusion porosimetry explored the detailed structural parameters of wood pore size distributions and assessed their fractal dimension. The results revealed significant variability in pore size distribution, porosity, pore volume, and fractal dimension values. The threshold pressure extracted from porosimetry data can be used as the main parameter to distinguish the pore size distribution regions. Pore sizes ranged from 3 to 35,000 nm, with a corresponding porosity that ranged from 58 to 76%. Three pore size classes were determined and ranged as: macropores (radius 350,000–5000 nm), mesopores (radius 5000–100 nm), and micropores (radius 100–3 nm). The fractal dimension values in the corresponding macropore, mesopore, and micropore size intervals were 2.98–2.998, 2.6–2.92, and 2.53–2.72, respectively, indicating a higher degree of complexity for larger pores.
Bio-lubricant production based on epoxidized oleic acid derived dated palm oil using in situ peracid mechanism
Authors: Tunku Ozir Tunku Arif Zafri , Bin Ab Kadir Mohd Zulkipli , Azmi Intan Suhada , Yeop Mohamad Zarqani , Rahman Siti Mariam A. , Jalil Mohd Jumain 
Published: October 2022

Abstract
In recent years, research on the epoxidation of fatty acids has attracted a great deal of attention due to the increased need for eco-friendly epoxides generated from vegetable oils. The purpose of this research is to produce bio-lubricant from optimized epoxidized oleic acid by alcoholysis with methanol, tert-butyl alcohol, and ethanolamine. Epoxidation is carried out using in situ performic acid formation under a constant temperature of 60 °C where formic acid acts as an oxygen carrier and hydrogen peroxide acts as an oxygen donor. The determination of the optimum process parameters uses one factor at a time (OFAT) method and is based on the optimized process parameters until the maximum relative conversion to oxirane of 65% is achieved. The bio-lubricants are confirmed using the Fourier Transform Infrared (FTIR) analysis and the results show that the hydroxyl group is present at 3400 cm−1 of wavenumber. A kinetic modeling is performed using the MATLAB optimization tool. After 100 iterations, the reaction rate constant based on optimized epoxidized dated palm oil production were obtained as follows: k
11 = 0.4251 mol⋅L−1⋅min−1, k
12 = 11.345 mol⋅L−1⋅min−1, and k
2 = 0.6761 mol⋅L−1⋅min−1.
Comparative toxic effect of bulk zinc oxide (ZnO) and ZnO nanoparticles on human red blood cells
Authors: Salami Maryam , Khosravi Maryam , Zarei Mohammad Hadi 
Published: October 2022

Abstract
Metal oxide nanoparticles (NPs) are a member of nanomaterials family that have been produced on a large scale and their toxicity affected by their high surface-to-volume ratio. The hemolytic toxic effects of metal oxide NPs may be completely different from those observed in their bulk counterparts. So, the main purpose of this research was to measure the difference between the hemolytic effects of ZnO (NPs and bulk) on isolated human red blood cells (RBCs). Hemolysis was measured after incubation of human RBCs with 0.01–1 mM of ZnO (bulk and NPs) for 6 h. For measurement of other variables, human RBCs were treated with 0.1 mM of ZnO (NPs and bulk) for 1, 2, and 3 h. Our results demonstrate that bulk ZnO did not show any toxic effects in the concentrations tested, while ZnO NPs caused toxic hemolytic effects through formation of ROS, lipid peroxidation, and glutathione depletion.
Prokop, ein glaubwürdiger Berichterstatter? Der Gotenkrieg im Ager Gallicus und im Picenum und seine Auswirkungen auf die Region
Authors: Oswald Pascal Dominic 
Published: October 2022

Abstract
By applying both traditional source analysis and archeological research this paper examines two questions related to the Gothic War in Picenum and Ager Gallicus: First, it deals with the credibility of Procopius’ reporting; second, it looks at the scope of the destructions caused by the 20-year-long conflict in the region and, hence, sheds light on the problem of whether the changes this war brought about – especially in contrast with the following invasion of the Lombards – justify the claim that its end clearly marked the transition from antiquity to the Middle Ages.
Crystal structure of (E)-3-(2-(4-(diethylamino)-2-hydroxystyryl)-3,3-dimethyl-3H-indol-1-ium-1-yl)propane-1-sulfonate – methanol (1/2), C25H32N2O4S⋅2CH3OH
Authors: Zhao Wen-Ze 
Published: October 2022

Abstract
C27H40N2O6S, monoclinic, P21/c (no. 14), a = 11.2654(15) Å, b = 21.630(3) Å, c = 12.2868(17) Å, β = 111.422(3)°, V = 2787.1(7) Å3, Z = 4, R
gt(F) = 0.0493, wR
ref(F
2) = 0.1313, T = 198(2) K.
Coordinated Regulation of CB1 Cannabinoid Receptors and Anandamide Metabolism Stabilizes Network Activity during Homeostatic Downscaling
Authors: Ye Michael , Monroe Sarah K. , Gay Sean M. , Armstrong Michael L. , Youngstrom Diane E. , Urbina Fabio L. , Gupton Stephanie L. , Reisdorph Nichole , Diering Graham H. 
Published: October 2022

AbstractNeurons express overlapping homeostatic mechanisms to regulate synaptic function and network properties in response to perturbations of neuronal activity. Endocannabinoids (eCBs) are bioactive lipids synthesized in the postsynaptic compartments to regulate synaptic transmission, plasticity, and neuronal excitability primarily through retrograde activation of presynaptic cannabinoid receptor type 1 (CB1). The eCB system is well situated to regulate neuronal network properties and coordinate presynaptic and postsynaptic activity. However, the role of the eCB system in homeostatic adaptations to neuronal hyperactivity is unknown. To address this issue, we used Western blotting and targeted lipidomics to measure adaptations in eCB system to bicuculline (BCC)-induced chronic hyperexcitation in mature cultured rat cortical neurons, and used multielectrode array (MEA) recording and live-cell imaging of glutamate dynamics to test the effects of pharmacological manipulations of eCB on network activities. We show that BCC-induced chronic hyperexcitation triggers homeostatic downscaling and a coordinated adaptation to enhance tonic eCB signaling. Hyperexcitation triggers first the downregulation of fatty acid amide hydrolase (FAAH), the lipase that degrades the eCB anandamide, then an accumulation of anandamide and related metabolites, and finally a delayed upregulation of surface and total CB1. Additionally, we show that BCC-induced downregulation of surface AMPA-type glutamate receptors (AMPARs) and upregulation of CB1 occur through independent mechanisms. Finally, we show that endocannabinoids support baseline network activities before and after downscaling and is engaged to suppress network activity during adaptation to hyperexcitation. We discuss the implications of our findings in the context of downscaling and homeostatic regulation ofin vitrooscillatory network activities.
Intramembrane client recognition potentiates the chaperone functions of calnexin
Authors: Bloemeke Nicolas , Meighen‐Berger Kevin , Hitzenberger Manuel , Bach Nina C , Parr Marina , Coelho Joao PL , Frishman Dmitrij , Zacharias Martin , Sieber Stephan A , Feige Matthias J 
Published: October 2022

AbstractOne‐third of the human proteome is comprised of membrane proteins, which are particularly vulnerable to misfolding and often require folding assistance by molecular chaperones. Calnexin (CNX), which engages client proteins via its sugar‐binding lectin domain, is one of the most abundant ER chaperones, and plays an important role in membrane protein biogenesis. Based on mass spectrometric analyses, we here show that calnexin interacts with a large number of nonglycosylated membrane proteins, indicative of additional nonlectin binding modes. We find that calnexin preferentially bind misfolded membrane proteins and that it uses its single transmembrane domain (TMD) for client recognition. Combining experimental and computational approaches, we systematically dissect signatures for intramembrane client recognition by calnexin, and identify sequence motifs within the calnexin TMD region that mediate client binding. Building on this, we show that intramembrane client binding potentiates the chaperone functions of calnexin. Together, these data reveal a widespread role of calnexin client recognition in the lipid bilayer, which synergizes with its established lectin‐based substrate binding. Molecular chaperones thus can combine different interaction modes to support the biogenesis of the diverse eukaryotic membrane proteome.
Sydney Harbour: Seiches, tides and mean circulation
Authors: Petrie Brian 
Published: October 2022

Beginning with observations from 1901, sea level elevations and currents from Sydney Harbour are examined across a broad frequency range. The mean currents, annual components of sea level, tides and seiches, mainly in the South Arm, are the focus. Tidal and mean currents are ~0.01 m s-1. The general circulation is estuarine-like with a thin, near-surface outflow layer and a thicker, deeper inflow. The distribution of contaminants in bottom sediments suggests the circulation, though weak, plays a retentive role in the Arm, transporting sediments towards its head. Analysis of 11-years of sea level data indicates a strong annual cycle, more energetic during winter than from late spring to early fall. The increased energy occurred at all frequencies except for tides. Seiches, with periods of ~0.5 to 2 h, emerge as a strong contributor to sea level and currents. The distributions of elevation and flow amplitudes associated with seiches were derived. With maximum observed values of 0.74 m and 0.24 m s-1, seiche displacements and currents can exceed those associated with tides and the mean circulation. While earlier studies identified only the dominant fundamental seiche mode, recent sea level data sampled at 1-minute show that modes 2-4 occur. Keywords: Sydney Harbour, sea level, mean circulation, tides, seiches