bluuebunny/crossref_metadata_2025_split huggingface dataset:
How common is acute pelvic fixation failure after adult spine surgery? A single-center study of 358 patients
Authors: Lee Nathan J. , Park Paul J. , Puvanesarajah Varun , Clifton William E. , Kwan Kevin , Morrissette Cole R. , Williams Jaques L. , Fields Michael W. , Leung Eric , Hassan Fthimnir M. , Angevine Peter D. , Mandigo Christopher E. , Lombardi Joseph M. , Sardar Zeeshan M. , Lehman Ronald A. , Lenke Lawrence G. 
Published: August 2022

OBJECTIVE
There is a paucity of literature on pelvic fixation failure after adult spine surgery in the early postoperative period. The purpose of this study was to determine the incidence of acute pelvic fixation failure in a large single-center study and to describe the lessons learned.

METHODS
The authors performed a retrospective review of adult (≥ 18 years old) patients who underwent spinal fusion with pelvic fixation (iliac, S2-alar-iliac [S2AI] screws) at a single academic medical center between 2015 and 2020. All patients had a minimum of 3 instrumented levels. The minimum follow-up was 6 months after the index spine surgery. Patients with prior pelvic fixation were excluded. Acute pelvic fixation failure was defined as revision of the pelvic screws within 6 months of the primary surgery. Patient demographics and operative, radiographic, and rod/screw parameters were collected. All rods were cobalt-chrome. All iliac and S2AI screws were closed-headed screws.

RESULTS
In 358 patients, the mean age was 59.5 ± 13.6 years, and 64.0% (n = 229) were female. The mean number of instrumented levels was 11.5 ± 5.5, and 79.1% (n = 283) had ≥ 6 levels fused. Three-column osteotomies were performed in 14.2% (n = 51) of patients, and 74.6% (n = 267) had an L5–S1 interbody fusion. The mean diameter/length of pelvic screws was 8.5/86.6 mm. The mean number of pelvic screws was 2.2 ± 0.5, the mean rod diameter was 6.0 ± 0 mm, and 78.5% (n = 281) had > 2 rods crossing the lumbopelvic junction. Accessory rods extended to S1 (32.7%, n = 117) or S2/ilium (45.8%, n = 164). Acute pelvic fixation failure occurred in 1 patient (0.3%); this individual had a broken S2AI screw near the head-neck junction. This 76-year-old woman with degenerative lumbar scoliosis and chronic lumbosacral zone 1 fracture nonunion had undergone posterior instrumented fusion from T10 to pelvis with bilateral S2AI screws (8.5 × 90 mm); i.e., transforaminal lumbar interbody fusion L4–S1. The patient had persistent left buttock pain postoperatively, with radiographically confirmed breakage of the left S2AI screw 68 days after surgery. Revision included instrumentation removal at L2–pelvis and a total of 4 pelvic screws.

CONCLUSIONS
The acute pelvic fixation failure rate was exceedingly low in adult spine surgery. This rate may be the result of multiple factors including the preference for multirod (> 2), closed-headed pelvic screw constructs in which large-diameter long screws are used. Increasing the number of rods and screws at the lumbopelvic junction may be important factors to consider, especially for patients with high risk for nonunion.
TREND MOMENT METHOD IN PREDICTING THE NUMBER OF SALES OF MATIC MOTORCYCLES
Authors: Yuma Febby Madonna 
Published: August 2022

Abstract: PT. Panca Niaga Mandiri is an authorized motorcycle dealer in Sei Piring which is engaged in selling Honda motorcycles both in cash and on credit. Dealer Problems PT. Tunas Dwipa Putra at this time is that there is no definite calculation to predict the motorcycle sales target each month and the problems that occur are that sometimes there is an increase or decrease in motorcycle sales for each month because currently, business competition is very tight so that it makes business people compete with each other in their way. Many strategies have been carried out by marketing for how monthly motorcycle sales continue to increase. Therefore, it is necessary to use a forecasting method to predict sales of Honda motorcycles, especially automatic-type Honda motorcycles. The method used is the Trend Moment method. It is hoped that this method can help predict sales of automatic motorcycles for the next month.Keywords: honda motorcycle; prediction; sales; Abstrak: PT. Panca Niaga Mandiri merupakan dealer resmi sepeda motor yang ada di Sei Piring yang bergerak pada penjualan sepeda motor honda baik secara tunai maupun secara kredit. Permasalahan Dealer PT. Tunas Dwipa Putra pada saat ini yaitu tidak adanya perhitungan yang pasti untuk memprediksi target penjualan motor disetiap bulannya dan permasalahan yang terjadi terkadang mengalami kenaikan maupun penurunan penjualan sepeda motor untuk setiap bulannya, Karena saat ini persaingan bisnis sangat ketat sekali sehingga membuat para pelaku bisnis saling bersaing dengan cara mereka sendiri. Banyak strategi yang sudah dilakukan oleh marketing untuk bagaimana penjualan sepeda motor setiap bulanya terus meningkat. Oleh karena itu, maka diperlukan metode peramalan untuk memprediksi penjualan sepeda motor honda khususnya sepeda motor honda type matic. Metode yang digunakan yaitu metode Trend Moment diharapakan metode ini dapat membantu dalam memprediksi penjualan sepeda motor matic untuk bulan kedepannya. Kata kunci:penjualan; prediksi;sepeda motor honda
Perancangan ERP Menu Hr-Training Berbasis Odoo Menggunakan Metode SDLC Studi Kasus PT.XYZ
Authors: Jamal Saeful , Kusnadi Kusnadi 
Published: August 2022

Dalam mengelola sumber daya manusia di dalam suatu perusahaan, dihadapi oleh berbagai permasalahan yang ada. Salah satunya adalah permasalahan administrasi dalam mengelola suatu sumberdaya manusia di dalam perusahaan. ERP memberikan suatu solusi bagaimana permasalahan tersebut dapat diatasi. Sehingga pengelolaan sumber daya manusia dalam suatu perusahaan dapat lebih terautomisasi. Salah satu permasalahan dalam mengelola sumber daya manusia adalah permasalahan bagaimana pengelolaan pelatihan pada karyawan. Mengingat banyaknya karyawan dan banyaknya materi pelatihan yang diberikan. Maka diperlukanlah suatu suatu rancangan manajemen ERP untuk mengelola bagaimana pelatihan pada karyawan. Adapun ERP yang digunakan adalah ERP berbasis Odoo, dimana Odoo merupakan ERP sumber terbuka, yang artinya bebas digunakan dan dikembangkan oleh siapapun secara gratis. Adapun pengembangan ERP ini menggunakan metode SDLC yang memiliki beberapa tahapan seperti tahap analisis, tahap desain, tahap implementasi, tahap pengujian, dan tahap pemeliharaan. Pada tahap analisis, dianalisis lebih lanjut mengenai kebutuhan apa yang yang ingin dikembangkan dalam sistem. Kemudian dilanjut dengan mendesain bagaimana sistem ini bekerja. Kemudian dilanjutkan dengan pengimplementasian bagaimana sistem ini diterapkan. Kemudian dilanjutkan dengan tahap pengujian, sehingga diketahui bagaimana hasil dari pengujian sistem yang telah diimplementasikan. Dan terakhir merupakan tahap pemeliharaan dimana sistem yang berjalan dilakukan pemeliharaan secara berkala pada sitem untuk melakukan pengembangan yang lebih baik kedepannya.
Aplikasi Absensi Mahasiswa dan Dosen Politeknik Ganesha Medan Berbasis Web Menggunakan PHP dan MySql
Authors: Ramadhan Wisnu , Putra Surya Hendra 
Published: August 2022

Masalah manipulasi absensi sering terjadi saat proses belajar mengajar, baik dilakukan mahasiswa maupun dosen itu sendiri, mahasiswa yang tidak datang masih bisa menitipkan tanda tangan ke teman sekelas, begitu juga dosen yang seharusnya tidak ada jam mengajar tetap membuat tanggal masuknya di absensi maupun berita acara pengajaran, sehingga terjadinya kesalahpahaman pihak akademik saat perekapan kehadiran mahasiswa maupun perekapan honor dosen.Laporan Magang ini bertujuan membuat aplikasi absensi mahasiswa dan dosen guna memudahkan dalam pelaporan mahasiswa dan dosen yang datang, juga dapat menyimpan hasil laporan sehingga pihak akademik dapat melihat kembali laporan kehadiran mahasiswa dan dosen bila diperlukan. Tahapan pembuatan yang dilakukan pada penelitian ini menggunakan metode waterfall dan berbasis website. Pembuatan aplikasi ini menggunakan prosedur pengolahan data, Data Flow Diagram, Flowchart dan peranganan Database. Output akhir dari rancangan system yang telah di usulkan yaitu meliputi laporan kehadiran dosen dan mahasiswa.
A thermostable and CBM2-linked GH10 xylanase from Thermobifida fusca for paper bleaching
Authors: Wu Xiuyun , Shi Zelu , Tian Wenya , Liu Mengyu , Huang Shuxia , Liu Xinli , Yin Hua , Wang Lushan 
Published: August 2022

Xylanases have the potential to be used as bio-deinking and bio-bleaching materials and their application will decrease the consumption of the chlorine-based chemicals currently used for this purpose. However, xylanases with specific properties could act effectively, such as having significant thermostability and alkali resistance, etc. In this study, we found that TfXyl10A, a xylanase from Thermobifida fusca, was greatly induced to transcript by microcrystalline cellulose (MCC) substrate. Biochemical characterization showed that TfXyl10A is optimally effective at temperature of 80 °C and pH of 9.0. After removing the carbohydrate-binding module (CBM) and linker regions, the optimum temperature of TfXyl10A-CD was reduced by 10°C (to 70°C), at which the enzyme’s temperature tolerance was also weakened. While truncating only the CBM domain (TfXyl10AdC) had no significant effect on its thermostability. Importantly, polysaccharide-binding experiment showed that the auxiliary domain CBM2 could specifically bind to cellulose substrates, which endowed xylanase TfXyl10A with the ability to degrade xylan surrounding cellulose. These results indicated that TfXyl10A might be an excellent candidate in bio-bleaching processes of paper industry. In addition, the features of active-site architecture of TfXyl10A in GH10 family were further analyzed. By mutating each residue at the -2 and -1 subsites to alanine, the binding force and enzyme activity of mutants were observably decreased. Interestingly, the mutant E51A, locating at the distal -3 subsite, exhibited 90% increase in relative activity compared with wild-type (WT) enzyme TfXyl10A-CD (the catalytic domain of TfXyl110A). This study explored the function of a GH10 xylanase containing a CBM2 domain and the contribution of amino acids in active-site architecture to catalytic activity. The results obtained provide guidance for the rational design of xylanases for industrial applications under high heat and alkali-based operating conditions, such as paper bleaching.
Multi-instrumental investigation of the solar flares impact on the ionosphere on 05–06 December 2006
Authors: Barta Veronika , Natras Randa , Srećković Vladimir , Koronczay David , Schmidt Michael , Šulic Desanka 
Published: August 2022

The sudden increase of X-radiation and EUV emission following solar flares causes additional ionization and increased absorption of electromagnetic (EM) waves in the Earth’s atmosphere. The solar flare impact on the ionosphere above Europe on 05 and 06 December 2006 was investigated using ground-based (ionosonde and VLF) and satellite-based data (Vertical Total Electron Content (VTEC) derived from GNSS observations and VLF measurements from DEMETER satellite). Based on the Kp and Dst indices, 05 December 2006 was a quiet day, while there was a geomagnetic storm on 06 December 2006. The total fade-out of the EM waves emitted by the ionosondes was experienced at all investigated stations during an X9 class flare on 05 December 2006. The variation of the fmin parameter (first echo trace observed on ionograms, it is a rough measure of the “non-deviative” absorption) and its difference between the quiet period and during the flares have been analyzed. A latitude dependent enhancement of fmin (2–9 MHz) and Δfmin (relative change of about 150%–300%) was observed at every station at the time of the X9 (on 05 December) and M6 (on 06 December) flares. Furthermore, we analyzed VTEC changes during and after the flare events with respect to the mean VTEC values of reference quiet days. During the X9 solar flare, VTEC increased depending on the latitude (2–3 TECU and 5%–20%). On 06 December 2006, the geomagnetic storm increased ionization (5–10 TECU) representing a “positive” ionospheric storm. However, an additional peak in VTEC related to the M6 flare could not be detected. We have also observed a quantifiable change in transionospheric VLF absorption of signals from ground transmitters detected in low Earth orbit associated with the X9 and M6 flare events on 05 and 06 December in the DEMETER data. Moreover, amplitude and phase of ground-based, subionospherically propagating VLF signals were measured simultaneously during the investigated flares to analyze ionosphere reaction and to evaluate the electron density profile versus altitude. For the X9 and M6 flare events we have also calculated the ionospheric parameters (sharpness, reflection height) important for the description and modelling of this medium under forced additional ionization.
Yield, nitrogen-use efficiency, and distribution of nitrate-nitrogen in the soil profile as influenced by irrigation and fertilizer nitrogen levels under zero-till wheat in the eastern Indo-Gangetic plains of India
Authors: Sahoo Samaresh , Mukhopadhyay P. , Sinha A. K. , Bhattacharya P. M. , Rakesh S. , Kumar Rajkishore , Padbhushan Rajeev , Bijay-Singh  , Parmar Brajendra , Vishwakarma Anand , Kumar Amarendra , Yadav Brahamdeo Kumar , Bhushan Shanti , Kumar Atul , Kaviraj Megha , Kumar Upendra 
Published: August 2022

Due to the introduction of zero-till wheat in the Indo-Gangetic plains (IGP) in India, irrigation and fertilizer nitrogen (N) management needs to be modified from that followed under conventionally tilled fields. A field experiment was conducted to study the effect of irrigation and N levels on yield and N uptake by zero-till wheat, fertilizer N-use efficiency, and distribution of nitrate-N (NO3-N) in a soil profile under zero-till conditions in an acidic alluvial soil of the eastern IGP. The experiment was laid out in a split-plot design with four levels of irrigation as main plots (I0-no irrigation, rain-fed, I1-122 mm in one irrigation at 21 days after sowing (DAS), I2-263 mm in two irrigations at 21 and 42 DAS, and I3-386 mm in three irrigations at 21, 42, and 84 DAS) and 4 N levels [0 (N0), 60 (N1), 120 (N2), and 150 (N3) kg N ha−1] as subplots. Grain and straw yields were significantly higher at the irrigation level-I2 and 120 kg N ha−1-N2 over the control (I0 and N0) and were at par with the highest applied levels of irrigation and N (I3 and N3). The nitrogen uptake by wheat followed a trend similar to yield for irrigation levels; however, it increased significantly up to 150 kg N ha−1. After the harvest of wheat crop, more NO3-N was observed in the 60–90 cm subsurface soil layer than in the surface 0–15 cm and/or 15–30 cm and 30–60 cm subsurface soil layers. The highest NO3-N concentration was recorded in the treatment I2N2. Accumulation of NO3-N in the soil increased up to irrigation levels I2 and with increasing doses of fertilizer N application. Combined applications of irrigation and N had a positive and significant influence on agronomic efficiency (AE) and apparent N recovery (ANR) but had no significant effect on physiological efficiency (PE). This study suggests that an appropriate combination of irrigation and N levels in zero-till wheat can lead to not only high-yield levels and N-use efficiency but also adequately control NO3-N leaching under acidic alluvial soils in the eastern IGP.
Construction of a novel Wheat 55 K SNP array-derived genetic map and its utilization in QTL mapping for grain yield and quality related traits
Authors: Fan Xiaoli , Liu Xiaofeng , Feng Bo , Zhou Qiang , Deng Guangbing , Long Hai , Cao Jun , Guo Shaodan , Ji Guangsi , Xu Zhibin , Wang Tao 
Published: August 2022

Wheat is one of the most important staple crops for supplying nutrition and energy to people world. A new genetic map based on the Wheat 55 K SNP array was constructed using recombinant inbred lines derived from a cross between Zhongkemai138 and Kechengmai2 to explore the genetic foundation for wheat grain features. This new map covered 2,155.72 cM across the 21 wheat chromosomes with 11,455 markers. And 2,846 specific markers for this genetic map and 148 coincident markers among different maps were documented, which was helpful for improving and updating wheat genetic and genomic information. Using this map, a total of 68 additive QTLs and 82 pairs of epistatic QTLs were detected for grain features including yield, nutrient composition, and quality-related traits by QTLNetwork 2.1 and IciMapping 4.1 software. Fourteen additive QTLs and one pair of epistatic QTLs could be detected by both software programs and thus regarded as stable QTLs here, all of which explained higher phenotypic variance and thus could be utilized for wheat grain improvement. Additionally, thirteen additive QTLs were clustered into three genomic intervals (C4D.2, C5D, and C6D2), each of which had at least two stable QTLs. Among them, C4D.2 and C5D have been attributed to the famous dwarfing geneRht2and the hardness locusPina, respectively, while endowed with main effects on eight grain yield/quality related traits and epistatically interacted with each other to control moisture content, indicating that the correlation of involved traits was supported by the pleotropic of individual genes but also regulated by the gene interaction networks. Additionally, the stable additive effect of C6D2 (QMc.cib-6D2andQTw.cib-6D2) on moisture content was also highlighted, potentially affected by a novel locus, and validated by its flanking Kompetitive Allele-Specific PCR marker, andTraesCS6D02G109500, encoding aleurone layer morphogenesis protein, was deduced to be one of the candidate genes for this locus. This result observed at the QTL level the possible contribution of grain water content to the balances among yield, nutrients, and quality properties and reported a possible new locus controlling grain moisture content as well as its linked molecular marker for further grain feature improvement.
Exploration of barriers to postnatal care service utilization in Debre Libanos District, Ethiopia: A descriptive qualitative study
Authors: Girma Tareke Kasahun , Feyissa Garumma Tolu , Kebede Yohannes 
Published: August 2022

BackgroundIn Ethiopia, postnatal care (PNC) service utilization was low although many interventions had been implemented. Previous studies showed community-/caregiver-related barriers to PNC service utilization, but limited evidence was available on the health facilities and health care provider-related barriers. Therefore, the study was aimed at exploring both community and health care provider-related barriers to PNC service utilization.MethodsA descriptive qualitative study was conducted at Debre Libanos District, Ethiopia, from 11 March to 7 April 2019. A purposive sampling technique was used to recruit study participants among recently delivered women (&lt;2 months), health care providers, and community members. A total of five in-depth interviews, 12 key informant interviews, and four FGDs were conducted. Data were audio-recorded, transcribed verbatim, and translated, and inductive thematic analysis was used to analyze the data using the atlas ti.7.1 software.ResultsA total of 51 participants were involved in the study. The findings were organized into two major themes: (1) Community/caregiver-related barriers to PNC service utilization: lack of awareness about PNC, its importance, and schedules; lack of awareness about postnatal danger signs, sociocultural and religious beliefs, topographical and transportation problems, non-functionality of the health developmental armies (HDA); (2) health facility and health care provider-related barriers to PNC service utilization: poor supportive supervision and monitoring, lack of health extension workers' (HEW) commitment, lack of an organized system to notify delivery to HEW, shortage of HEWs, the residence of the HEWs, closure of health posts (HP) on working hours, and non-functionality of HPs.ConclusionsThe study findings underscore the need to develop different strategies and take actions. Therefore, the health centers and district health offices should have to assign the required number of HEWs at HPs, regularly supervise and monitor HEWs, and develop an organized system to facilitate early notification of delivery to HEWs. The HEWs should have to live near the HP, re-organize HDAs, create awareness of maternal and newborn danger signs, and conduct social and behavioral change communications to increase the health-seeking behavior of community members for utilizing PNC services.
Construction of an easily detectable transgenic Synechococcus elongatus PCC 7942 against White Spot Syndrome Virus using vp28 and mOrange Gene and its metabolism in shrimp
Authors: Peng Wen , Bao Qunjing , Jia Rui , He Peimin 
Published: August 2022

White spot syndrome is an epidemic disease caused by the highly contagious and lethal white spot syndrome virus (WSSV), resulting in huge economic losses to the global aquaculture industry. VP28 is the main structural protein in the capsule of WSSV and is important in the early stage of infection. Under an excitation wavelength of 548 nm, the mOrange fluorescent protein releases a 562 nm emission wavelength, which is different from the autofluorescence of cyanobacteria. Therefore, using this characteristic combined with the receptor system of Synechococcus elongatus PCC 7942, we constructed transgenic S. elongatus to express the recombinant protein VP28-mOrange. In addition, PCR and western blotting were used to confirm the stable expression of the target gene in cyanobacteria. Using mOrange tracer features, we explored the recombinant protein VP28-mOrange in the metabolic cycle of young Litopenaeus Vannamei after feeding. After the young shrimp had stopped consuming transgenic cyanobacteria, the 24 to 33 h fluorescence signal in the intestine was very weak, and almost disappeared after 36 h. We explored the protective effect of transgenic vp28-mOrange S. elongatus within 48 h of being ingested by L. vannamei and set WSSV challenges at 2, 12, 24, and 48 h post-immunization. However, the survival rate of L. vannamei decreased as the time of the WSSV challenge increased. The survival rate on the seventh day was 81%, 52%, 45.5%, and 33.3% for shrimps challenged for 2, 12, 24, and 48 h, respectively. Enzyme activity can also support this conjecture, the enzyme activity indexes of the experimental groups were significantly reduced compared to positive and wild-type controls. Therefore, this immune agent functioned as a preventive agent. Compared with the traditional method, this method was easy to detect and can visualize the digestion of transgenic cyanobacteria in the Litopenaeus vannamei intestine.