bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotion regulation difficulties moderate the effects of pandemic-related factors on stress and anxiety during the COVID-19 Pandemic
Authors: Judy Kristen , McGinley Jared , Llera Sandra 
Published: April 2022

Aim of the studyThe COVID-19 pandemic has impacted many people’s standard operating procedures in ways that require behavioral and psychological adjustments. Research indicates widespread stress and anxiety during the pandemic. What is still less known is which pandemic-influenced factors are most directly impacting psychological wellbeing, and whether emotion regulation abilities are moderating this impact.Subject or material and methods182 participants were recruited through Amazon Mechanical Turk (MTurk) to complete an online survey composed of assessments of perceived stress, state anxiety, emotion regulation abilities, and pandemic-related behavioral and lifestyle impacts.ResultsMultiple behavioral and lifestyle impacts were significant predictors of both stress and state anxiety. Additionally, emotion regulation difficulty moderated the relationship between several pandemic-related predictors and both stress and anxiety.DiscussionThe current study provides evidence that emotion regulation moderates the degree to which pandemic-related changes impact stress and state anxiety.ConclusionsEmphasizing adaptive emotion regulation strategies may strengthen one’s ability to cope with these pandemic-related changes and increase mental wellbeing, although even these strategies might have limited efficacy during periods of greater disruption.
Liberalizing and harmful interventions in international trade: case of Poland
Authors: Piekutowska Agnieszka 
Published: April 2022

Motivation: As there is a need to track and analysis — with its practical implications — the responsibility for actions affecting international trade, therefore exploration of trade interventions implemented by Poland has its justification.
Aim: The aim of the paper is to reveal direction, scale and dynamics of both liberalizing and harmful interventions in international trade implemented by Poland. The goal to achieve is to answer crucial question: to what extent, EU protectionism is shaped by EU bodies only — and to what extent by Poland by itself.
Results: An analysis reveals both country-specific direction of interventions as well as country-specific sectors affected by liberalizing and harmful interventions. Although part of all interventions is those of EU bodies, Poland uses for instance state aid to stimulate national businesses as not all kinds of state aid are forbidden by EU law (types listed on not so short list in Article 107 of TFEU). Thus, as member states differ in their economic interests, one can observe differentiation in state interventions in scope of international trade.
Disclosure requirements and their assessment by SMEs traded on alternative markets in Poland (NewConnect) and Germany (m:access)
Authors: Śliwiński Paweł , Woźniak Sonia 
Published: April 2022

Motivation: Financial access limitations are a main barrier to the development of SMEs. One of the methods of bridging the capital gap is SME access to the stock markets, in particular to an alternative market (MTF). Compared to regulated markets, MTFs offer more liberal entry conditions and in many cases prior to MAR implementation they proposed more liberal disclosure requirements.
Aim: The aim of the article is to analyze the disclosure requirements resulting from MAR directive and to test their perception by issuers listed on the alternative markets in Poland (NewConnect) and Germany (m:access). The research focused on the assessment of difficulties in performing disclosure requirements and checking whether there is a difference in perceiving the scale of difficulties in fulfilling disclosure duties in both countries.
Results: Analysed markets are subject to MAR, so as a rule, there are no differences in the reporting requirements. There is, however, a difference in perceiving them in both countries. The analysis of German issuers shows that, unlike Polish companies, most of them defined their disclosure obligations as simple. This may result from higher knowledge of the regulations than in Poland. The opinion on disclosure requirements by NewConnect issuers had an impact on the amount of time and human resources devoted to disclosure obligations. The research has also shown that issuers in both markets generally assess well the cooperation with authorized advisers who help them, inter alia, in disclosure obligations.
Strategic Reviews
Authors: Mostagir Mohamed , Siderius James 
Published: April 2022

The impact of product reviews on consumer purchasing behavior is empirically well documented. This can create perverse incentives for firms to offer reviewers side payments (“bribes”) in exchange for biased reviews for their products. The presence of bribes distorts the information in reviews and leads to detrimental effects on consumer utility. This paper builds a two-sided reputation model where a reviewer can inflate her reviews in exchange for bribes. If the reviewer accepts bribes and misrepresents her reviews, then she builds her reputation as an inaccurate reviewer and makes consumers less likely to follow her recommendations. This in turn makes firms no longer interested in offering her a bribe. Can the reviewer retain influence over consumers’ purchasing decisions while simultaneously accepting bribes and misrepresenting her reviews? We provide a characterization of the environments that allow this kind of manipulation and show that regulatory policies that aim to reduce bribes can lead to undesirable outcomes. Finally, we show that eliminating bribes from the market can increase the welfare of all market participants, even for those firms who would have otherwise bribed in exchange for more favorable reviews. This paper was accepted by Gabriel Weintraub, revenue management and market analytics. Supplemental Material: The online appendix is available at https://doi.org/10.1287/mnsc.2022.4376 .
Technical Note—Stochastic Scheduling with Abandonment: Necessary and Sufficient Conditions for the Optimality of a Strict Priority Policy
Authors: Chen Gang , Gayon Jean-Philippe , Lemaire Pierre 
Published: April 2022

Strict priority policies in a stochastic system with abandonment In the technical note “Stochastic scheduling with abandonment: Necessary and sufficient conditions for the optimality of a strict priority policy,” Chen, Gayon, and Lemaire consider a stochastic scheduling problem in which jobs abandon when their waiting time exceeds their lifetime. Such a problem arises, for example, in call centers or emergency systems. It is known that the optimal policy is a strict priority policy under some sets of conditions. The authors provide the first set of necessary and sufficient conditions for a problem with two types of jobs. They also provide conjectures to guide toward generalizations of the proposed conditions.
Manufacturing Popularity: An Ecological Model of Time-Based Competition
Authors: Barnett William P. , Rhee Mooweon , Tak Elise 
Published: April 2022

Many markets are characterized by the rapid coming and going of successive products, each lasting in the market for only a short period of time before it is replaced by another. Such markets confront firms with the strategic challenge of trying to enhance the success and longevity of their products. We develop a model to understand such time-based competition among products and how it is shaped by different organizational strategies. We estimate the model using data on Korean popular music. The results highlight the importance of social exposure to a transitory product’s chances of becoming and remaining popular. They also show that efforts by large organizations to manufacture popularity in that context have triggered a self-defeating dynamic. These efforts not only improve the competitiveness of songs trying to become popular but also increase competition from rival songs, thereby intensifying the brevity of success.Funding: This research was supported by the Stanford Graduate School of Business, as well as an International Joint Research Grant by Yonsei Graduate School [to Rhee].
Total knee arthroplasty in patients with severe obesity provides value for money despite increased complications
Authors: Elcock Katie L. , Carter Thomas H. , Yapp Liam Z. , MacDonald Deborah J. , Howie Colin R. , Stoddart Andrew , Berg Guy , Clement Nick D. , Scott Chloe E. H. 
Published: April 2022

Aims Access to total knee arthroplasty (TKA) is sometimes restricted for patients with severe obesity (BMI ≥ 40 kg/m2). This study compares the cost per quality-adjusted life year (QALY) associated with TKA in patients with a BMI above and below 40 kg/m2 to examine whether this is supported. Methods This single-centre study compared 169 consecutive patients with severe obesity (BMI ≥ 40 kg/m2) (mean age 65.2 years (40 to 87); mean BMI 44.2 kg/m2 (40 to 66); 129/169 female) undergoing unilateral TKA to a propensity score matched (age, sex, preoperative Oxford Knee Score (OKS)) cohort with a BMI < 40 kg/m2 in a 1:1 ratio. Demographic data, comorbidities, and complications to one year were recorded. Preoperative and one-year patient-reported outcome measures (PROMs) were completed: EuroQol five-dimension three-level questionnaire (EQ-5D-3L), OKS, pain, and satisfaction. Using national life expectancy data with obesity correction and the 2020 NHS National Tariff, QALYs (discounted at 3.5%), and direct medical costs accrued over a patient’s lifetime, were calculated. Probabilistic sensitivity analysis (PSA) was used to model variation in cost/QALY for each cohort across 1,000 simulations. Results All PROMs improved significantly (p < 0.05) in both groups without differences between groups. Early complications were higher in BMI ≥ 40 kg/m2: 34/169 versus 52/169 (p = 0.050). A total of 16 (9.5%) patients with a BMI ≥ 40 kg/m2 were readmitted within one year with six reoperations (3.6%) including three (1.2%) revisions for infection. Assuming reduced life expectancy in severe obesity and revision costs, TKA in patients with a BMI ≥ 40 kg/m2 costs a mean of £1,013/QALY (95% confidence interval £678 to 1,409) more over a lifetime than TKA in patients with BMI < 40 kg/m2. In PSA replicates, the maximum cost/QALY was £3,921 in patients with a BMI < 40 kg/m2 and £5,275 in patients with a BMI ≥ 40 kg/m2. Conclusion Higher complication rates following TKA in severely obese patients result in a lifetime cost/QALY that is £1,013 greater than that for patients with BMI < 40 kg/m2, suggesting that TKA remains a cost-effective use of healthcare resources in severely obese patients where the surgeon considers it appropriate. Cite this article: Bone Joint J 2022;104-B(4):452–463.
Management of periprosthetic fractures of the humerus
Authors: Mourkus Hany , Phillips Nick J. , Rangan Amar , Peach Chris A. 
Published: April 2022

Aims The aim of this study was to investigate the outcome of periprosthetic fractures of the humerus and to assess the uniformity of the classifications used for these fractures (including those around elbow and/or shoulder arthroplasties) by performing a systematic review of the literature. Methods A systematic search was conducted using the National Institute for Health and Care Excellence Healthcare Databases Advance Search. For inclusion, studies had to report clinical outcomes following the management of periprosthetic fractures of the humerus. The protocol was registered on the PROSPERO database. Results Overall, 40 studies were included, involving a total of 210 patients. The fractures were reported using very heterogeneous classification systems, as were the functional outcome scores. A total of 60 patients had nonoperative treatment with a 50% rate of nonunion. Fixation was undertaken in 99 patients; successful union was obtained in 93 (93%). Revision of either the humeral stem or the whole arthroplasty was reported in 79 patients with a high rate of union (n = 66; 84%), and a mean rate of complications of 29% (0% to 41%). Conclusion This study highlighted a lack of uniformity in classifying these fractures and reporting the outcome of their treatment. The results may help to inform decision-making with patients, particularly about the rate of complications of nonoperative treatment. There is a need to improve the reporting of the pattern of these fractures using a uniform classification system, and the harmonization of the collection of data relating to the outcome of treatment. Based on this review, we propose a minimum dataset to be used in future studies. Cite this article: Bone Joint J 2022;104-B(4):416–423.
Does cumulative topical antibiotic powder use increase the risk of drug induced acute kidney injury in fracture patients?
Authors: O'Hara Nathan N. , Carullo Jessica , Joshi Manjari , Banoub Mary , Claeys Kimberly C. , Sprague Sheila , Slobogean Gerard P. , O'Toole Robert V. ,   PREP-IT Investigators
Published: April 2022

Aims There is increasing evidence to support the use of topical antibiotics to prevent surgical site infections. Although previous research suggests a minimal nephrotoxic risk with a single dose of vancomycin powder, fracture patients often require multiple procedures and receive additional doses of topical antibiotics. We aimed to determine if cumulative doses of intrawound vancomycin or tobramycin powder for infection prophylaxis increased the risk of drug-induced acute kidney injury (AKI) among fracture patients. Methods This cohort study was a secondary analysis of single-centre Program of Randomized Trials to Evaluate Pre-operative Antiseptic Skin Solutions in Orthopaedic Trauma (PREP-IT) trial data. We included patients with a surgically treated appendicular fracture. The primary outcome was drug-induced AKI. The odds of AKI per gram of vancomycin or tobramycin powder were calculated using Bayesian regression models, which adjusted for measured confounders and accounted for the interactive effects of vancomycin and tobramycin. Results Of the 782 included patients (mean age 48 years (SD 20); 59% male), 83% (n = 648) received at least one vancomycin dose (cumulative range 1 to 12 g). Overall, 45% of the sample received at least one tobramycin dose (cumulative range 1.2 to 9.6 g). Drug-induced AKI occurred in ten patients (1.2%). No association was found between the cumulative dose of vancomycin and drug-induced AKI (odds ratio (OR) 1.08 (95% credible interval (CrI) 0.52 to 2.14)). Additional doses of tobramycin were associated with a three-fold increase in the adjusted odds of drug-induced AKI (OR 3.66 (95% CrI 1.71 to 8.49)). Specifically, the risk of drug-induced AKI rose substantially after 4.8 g of tobramycin powder (7.5% (95% CrI 1.0 to 35.3)). Conclusion Cumulative doses of vancomycin were not associated with an increased risk of drug-induced AKI among fracture patients. While the risk of drug-induced AKI remains less than 4% with three or fewer 1.2 g tobramycin doses, the estimated risk increases substantially to 8% after four cumulative doses. Level of evidence: Therapeutic Level III Cite this article: Bone Jt Open 2022;3(4):284–290.
Static and dynamic disturbance compensation for optical misalignment of large ground-based wide field survey telescope
Authors: Cao Yuyan , Wang Jianli , Fan Wenqiang , Wang Zhichen , Wang Honghao , Liu Yang , Wang Fuguo , Li Hongwen , Xu Wei 
Published: April 2022

For large ground-based telescopes, static and dynamic disturbances would greatly degrade the optical performance. This is especially true for wide field survey telescopes with prime focus optics. The estimation of disturbance effects on large telescopes is becoming increasingly important during the design phase. Therefore, a wide field survey telescope with 2.5 m aperture and 3.5 deg field of view is studied in this research. This telescope is under construction now, and its first light is expected at the beginning of 2023. The estimation method for the optical performance under static and dynamic disturbances in the temporal domain and the active compensation method to improve the optical alignment, are investigated, which is a supplement for the simulation in the frequency domain. First, based on the mechanical model, the optical misalignment is established, where the deviation of the primary mirror is obtained from the length gauges and the deviation of the corrector is computed using the fitting method. Second, a method for compensating the static and dynamic disturbances is proposed, improving the optical performance. This method uses the disturbed primary mirror as the reference, and the corrector is actively controlled to align with it. Finally, a series of experimental tests and numerical simulations is conducted. The results show that the mechanical modeling error is within 10% and the maximum optical misalignment is reduced from

12

′
′

/

0.27

to

0.2

′
′

/

0.006

m
m

for static disturbance and from

1.3

′
′

/

0.03

to

0.4

′
′

/

0.01

m
m

for dynamic disturbance. Through active compensation, the telescope optical property is greatly improved. The modeling method and the simulation process mentioned in this research can also be used in the other relevant fields.
Magnitude and associated factors of urinary tract infections among adults living with HIV in Ethiopia. Systematic review and meta-analysis
Authors: Birhanu Molla Yigzaw , Habtegiorgis Samuel Derbie , Gietaneh Wodaje , Alemu Simegn , Tsegaye Tesfa Birlew , Bekele Getamesay Molla , Abebaw Abtie , Dilnessa Tebelay , Elmneh Haymanot Tewabe , Amha Haile , Bekele Ketema Daniel , Gebre Anto Tsige , Desta Melaku , Jemberie Selamawit Shita 
Published: April 2022

Background
Urinary tract infection is a major public health problem in developing countries among immunocompromized populations where there are limited health-care services. People living with human immunodeficiency virus (HIV) are more likely to develop urinary tract infections (UTI) due to the suppression of their immunity. There is no single representative figure as well as the presence of significant heterogeneity among studies conducted on people living with HIV in Ethiopia. Hence, this study tried to pool the magnitude of UTI among people living with HIV in Ethiopia.

Method
To find relevant studies, researchers looked through Web of Science, Science Direct, PubMed, EMBASE, the Cochrane Library, Google Scholar, and Worldwide Science. The I2 statistic was used to examine for heterogeneity among the studies that were included. To evaluate the pooled effect size across studies, a random-effects model was used. The presence of publication bias was determined using a funnel plot and Egger’s regression test. STATATM version 14.0 software was used for all statistical analyses.

Results
A total of 7 studies with 2257 participants were included in this meta-analysis. UTI was shown to be prevalent in 12.8% (95% CI: 10.8–14.79, I2 = 50.7%) of HIV patients. Being male (0.35, 95% CI:0.14, 1.02), rural residents(OR:1.41,95% CI: 0.85, 2.34), no history of catheterization (OR: 0.35, 95% CI: 0.06, 1.85), had no history of DM (OR:0.84, 95% CI:0.12, 0.597) and having CD4 count greater than 200 (OR:0.36 95% CI: 0.06, 2.35) were the factors which were the associated factors assessed and having association with UTI among people living with HIV but not statistically significant.

Conclusions
In Ethiopia, one in every eight HIV-positive people is at risk of acquiring UTI. Regardless, we looked for a link between sex, residency, CD4, catheterization history, and DM and UTI, but there was none. To avoid this phenomina, every HIV patient should have a UTI examination in every follow-up.
The efficacy and safety of roxadustat for the treatment of anemia in non-dialysis dependent chronic kidney disease patients: An updated systematic review and meta-analysis of randomized clinical trials
Authors: Abdelazeem Basel , Shehata Joseph , Abbas Kirellos Said , El-Shahat Nahla Ahmed , Malik Bilal , Savarapu Pramod , Eltobgy Mostafa , Kunadi Arvind 
Published: April 2022

Background
Roxadustat (ROX) is a new medication for anemia as a complication of chronic kidney disease (CKD). Our meta-analysis aims to evaluate the efficacy and safety of ROX, especially on the cardiovascular risks, for anemia in NDD-CKD patients.

Methods
Electronic databases were searched systematically from inception to July 2021 to look for randomized control trials (RCTs) that evaluated ROX NDD-CKD patients. Hemoglobin level and iron utilization parameters, including ferritin, serum iron, transferrin saturation (TSAT), total iron-binding capacity (TIBC), transferrin, and hepcidin were analyzed for efficacy. Pooled risk ratios (RRs) and standardized mean differences (SMDs) were calculated and presented with their 95% confidential intervals (CIs).

Results
Nine RCTs included a total of 3,175 patients in the ROX group and 2,446 patients in the control group. When compared the control group, ROX increased Hb level significantly (SMD: 1.65; 95% CI: 1.08, 2.22; P< 0.00001) and improved iron utilization parameters by decreasing ferritin (SMD: -0.32; 95% CI: -0.51, -0.14; P = 0.0006), TSAT (SMD: -0.19; 95% CI: -0.32, -0.07; P = 0.003), and hepcidin (SMD: -0.74; 95% CI: -1.09, -0.39; P< 0.0001) and increasing TIBC (SMD: 0.99; 95% CI: 0.76, 1.22; P< 0.00001) and transferrin (SMD: 1.20; 95% CI: 0.70, 1.71; P< 0.00001). As for safety, ROX was associated with higher serious adverse effects (RR: 1.07; 95% CI: 1.01, 1.13; P = 0.01), deep venous thrombosis (DVT) (RR: 3.80; 95% CI: 1.5, 9.64; P = 0.08), and hypertension (HTN) (RR: 1.37; 95% CI: 1.13, 1.65; P = 0.001).

Conclusion
We concluded that ROX increased Hb level and improved iron utilization parameters in NDD-CKD patients, but ROX was associated with higher serious adverse effects, especially DVT and HTN. Our results support the use of ROX for NDD-CKD patients with anemia. However, higher-quality RCTs are still needed to ensure its safety and risk of thrombosis.