bluuebunny/crossref_metadata_2025_split huggingface dataset:
Negative affect increases reanalysis of conflicts between discourse context and world knowledge
Authors: Lai Vicky Tzuyin , van Berkum Jos , Hagoort Peter 
Published: December 2022

IntroductionMood is a constant in our daily life and can permeate all levels of cognition. We examined whether and how mood influences the processing of discourse content that is relatively neutral and not loaded with emotion. During discourse processing, readers have to constantly strike a balance between what they know in long term memory and what the current discourse is about. Our general hypothesis is that mood states would affect this balance. We hypothesized that readers in a positive mood would rely more on default world knowledge, whereas readers in a negative mood would be more inclined to analyze the details in the current discourse.MethodsParticipants were put in a positive and a negative mood via film clips, one week apart. In each session, after mood manipulation, they were presented with sentences in discourse materials. We created sentences such as “With the lights on you can see...” that end with critical words (CWs) “more” or “less”, where general knowledge supports “more”, not “less”. We then embedded each of these sentences in a wider discourse that does/does not support the CWs (a story about driving in the night vs. stargazing). EEG was recorded throughout.ResultsThe results showed that first, mood manipulation was successful in that there was a significant mood difference between sessions. Second, mood did not modulate the N400 effects. Participants in both moods detected outright semantic violations and allowed world knowledge to be overridden by discourse context. Third, mood modulated the LPC (Late Positive Component) effects, distributed in the frontal region. In negative moods, the LPC was sensitive to one-level violation. That is, CWs that were supported by only world knowledge, only discourse, and neither, elicited larger frontal LPCs, in comparison to the condition where CWs were supported by both world knowledge and discourse.DiscussionThese results suggest that mood does not influence all processes involved in discourse processing. Specifically, mood does not influence lexical-semantic retrieval (N400), but it does influence elaborative processes for sensemaking (P600) during discourse processing. These results advance our understanding of the impact and time course of mood on discourse.
Genetic characterization of juvenile sudden cardiac arrest and death in Tuscany: The ToRSADE registry
Authors: Girolami Francesca , Spinelli Valentina , Maurizi Niccolò , Focardi Martina , Nesi Gabriella , Maio Vincenza , Grifoni Rossella , Albora Giuseppe , Bertaccini Bruno , Targetti Mattia , Coppini Raffaele , Favilli Silvia , Olivotto Iacopo , Cerbai Elisabetta 
Published: December 2022

BackgroundSudden cardiac arrest (SCA) in young people represents a dramatic event, often leading to severe neurologic outcomes or sudden cardiac death (SCD), and is frequently caused by genetic heart diseases. In this study, we report the results of the Tuscany registry of sudden cardiac death (ToRSADE) registry, aimed at monitoring the incidence and investigating the genetic basis of SCA and SCD occurring in subjects &lt; 50 years of age in Tuscany, Italy.Methods and resultsCreation of the ToRSADE registry allowed implementation of a repository for clinical, molecular and genetic data. For 22 patients, in whom a genetic substrate was documented or suspected, blood samples could be analyzed; 14 were collected at autopsy and 8 from resuscitated patients after SCA. Next generation sequencing (NGS) analysis revealed likely pathogenetic (LP) variants associated with cardiomyopathy (CM) or channelopathy in four patients (19%), while 17 (81%) carried variants of uncertain significance in relevant genes (VUS). In only one patient NGS confirmed the diagnosis obtained during autopsy: the p.(Asn480Lysfs*20) PKP2 mutation in a patient with arrhythmogenic cardiomyopathy (AC).ConclusionSystematic genetic screening allowed identification of LP variants in 19% of consecutive patients with SCA/SCD, including subjects carrying variants associated with hypertrophic cardiomyopathy (HCM) or AC who had SCA/SCD in the absence of structural cardiomyopathy phenotype. Genetic analysis combined with clinical information in survived patients and post-mortem evaluation represent an essential multi-disciplinary approach to manage juvenile SCD and SCA, key to providing appropriate medical and genetic assistance to families, and advancing knowledge on the basis of arrhythmogenic mechanisms in inherited cardiomyopathies and channelopathies.
Follow-up study of neuropsychological scores of infant patients with cobalamin C defects and influencing factors of cerebral magnetic resonance imaging characteristics
Authors: Chen Tao , Sui Chaofan , Lin Suna , Guo Bin , Wang Yuanyuan , Yang Linfeng 
Published: December 2022

PurposeThe purpose of this study was to investigate whether baseline cerebral magnetic resonance imaging (MRI) characteristics could predict therapeutic responsiveness in patients with cobalamin C (cblC) defects.Materials and methodsThe cerebral MRI results of 40 patients with cblC defects were evaluated by a neuroradiologist. Neuropsychological scores and imaging data were collected. Neuropsychological tests were performed before and after standardized treatment.ResultsThirty-eight patients initially underwent neuropsychological testing [developmental quotient (DQ)]. CblC defects with cerebellar atrophy, corpus callosum thinning and ventricular dilation had significantly lower DQs than those without (P &lt; 0.05). Through a multivariate linear stepwise regression equation after univariate analysis, ventricular dilation was the most valuable predictor of lower DQs. Thirty-six patients (94.7%) underwent follow-up neuropsychological testing. The pre- and post-treatment DQ values were not significantly different (Z = −1.611, P = 0.107). The post-treatment DQ classification (normal, moderately low, or extremely low) showed nearly no change compared to the pretreatment DQ classification (k = 0.790, P &lt; 0.001).ConclusionVentricular dilation, cerebral atrophy and corpus callosum thinning are the main MRI abnormalities of cblC defects, and these manifestations are significantly correlated with delayed development in children. MRI findings can be considered an important tool for determining the severity of cblC defects.
Global research status and frontiers on microvascular invasion of hepatocellular carcinoma: A bibliometric and visualized analysis
Authors: He Tao , Zou Jieyu , Sun Ke , Yang Juan , Lei Tingting , Xu Lin , Liu Jinheng , Yin Sineng , Li Guangkuo 
Published: December 2022

IntroductionOver the past decade, several studies on the microvascular invasion (MVI) of hepatocellular carcinoma (HCC) have been published. However, they have not quantitatively analyzed the remarkable impact of MVI. Therefore, a more comprehensive understanding of the field is now needed. This study aims to analyze the evolution of HCC-MVI research and to systematically evaluate the scientific outputs using bibliometric citation analysis.MethodsA systematic search was conducted on the Web of Science Core Collection on 2 May 2022 to retrieve studies on HCC-MVI published between 2013 and 2022. Then, a bibliometric analysis of the publications was performed using CiteSpace, VOSviewer, and other visualization tools.ResultsA total of 1,208 articles on HCC MVI were identified. Of these, China (n = 518) was the most prolific country, and Fudan University (n = 90) was the most notable institution. Furthermore, we observed that Lau Wan Yee participated in most studies (n = 26), and Frontiers in Oncology (IF2020:6.24) published the highest number of documents (n = 49) on this subject, with 138 publications. The paper “Bray F, 2018, CA-CANCER J CLIN, V68, P394” has the highest number of co-cited references, with 119 citations. In addition, the top three keywords were “survival”, “recurrence”, and “microvascular invasion”. Moreover, the research hot spots and frontiers of HCC-MVI for the last 3 years included imaging characteristics and transarterial chemoembolization (TACE) therapy studies.ConclusionsThis study comprehensively summarized the most significant HCC-MVI documents from past literature and highlighted key contributions made to the advancement of this subject and the advancement of this field over the past decade. The trend of MVI research will gradually shift from risk factors and prognosis studies to imaging characteristics and TACE therapy studies.
Genome-wide identification and characterization of the NPF genes provide new insight into low nitrogen tolerance in Setaria
Authors: Cheng Jinjin , Tan Helin , Shan Meng , Duan Mengmeng , Ye Ling , Yang Yulu , He Lu , Shen Huimin , Yang Zhirong , Wang Xingchun 
Published: December 2022

IntroductionNitrogen (N) is essential for plant growth and yield production and can be taken up from soil in the form of nitrate or peptides. The NITRATE TRANSPORTER 1/PEPTIDE TRANSPORTER family (NPF) genes play important roles in the uptake and transportation of these two forms of N.MethodsBioinformatic analysis was used to identify and characterize the NPF genes in Setaria. RNA-seq was employed to analyze time-series low nitrate stress response of the SiNPF genes. Yeast and Arabidopsis mutant complementation were used to test the nitrate transport ability of SiNRT1.1B1 and SiNRT1.1B2.ResultsWe identified 92 and 88 putative NPF genes from foxtail millet (Setaria italica L.) and its wild ancestor green foxtail (Setaria viridis L.), respectively. These NPF genes were divided into eight groups according to their sequence characteristics and phylogenetic relationship, with similar intron-exon structure and motifs in the same subfamily. Twenty-six tandem duplication and 13 segmental duplication events promoted the expansion of SiNPF gene family. Interestingly, we found that the tandem duplication of the SiNRT1.1B gene might contribute to low nitrogen tolerance of foxtail millet. The gene expression atlas showed that the SiNPFs were divided into two major clusters, which were mainly expressed in root and the above ground tissues, respectively. Time series transcriptomic analysis further revealed the response of these SiNPF genes to short- and long- time low nitrate stress. To provide natural variation of gene information, we carried out a haplotype analysis of these SiNPFs and identified 2,924 SNPs and 400 InDels based on the re-sequence data of 398 foxtail millet accessions. We also predicted the three-dimensional structure of the 92 SiNPFs and found that the conserved proline 492 residues were not in the substrate binding pocket. The interactions of SiNPF proteins with NO3− were analyzed using molecular docking and the pockets were then identified. We found that the SiNPFs NO3− binding energy ranged from-3.4 to -2.1 kcal/mol.DiscussionTaken together, our study provides a comprehensive understanding of the NPF gene family in Setaria and will contribute to function dissection of these genes for crop breeding aimed at improving high nitrogen use efficiency.
The relationship between gratitude and adolescents’ prosocial behavior: A moderated mediation model
Authors: Zhang Ding 
Published: December 2022

IntroductionThe development of prosocial behavior is an important embodiment of youth socialization. Cultivating adolescents’ prosocial behaviors can be beneficial to individuals form correct outlook on life and values, and has a profound impact on promoting the harmonious development of society.MethodsThis manuscript constructs a model to explain the mediating role of sense of meaning in life between gratitude and prosocial behavior and the moderating role of self-esteem in the mediating path. From the analysis of the data of 2,735 questionnaires utilizing SPSS 22.Results(1) Gratitude has a significant positive effect on prosocial behavior; (2) sense of meaning in life plays a mediating influence on the relationship between gratitude and prosocial behavior; and (3) self-esteem has a moderating impact on relationship between sense of meaning in life and prosocial behavior, which means that adolescents with high self-esteem experience a stronger positive effect of a sense of life’s meaning on their prosocial behavior.DiscussionThese findings not only add to research on the relationship between gratitude and prosocial behavior, but also provide ideas for improving adolescent prosocial behavior. Theoretical and practical implications, along with limitations and future research directions, were discussed.
Structural validity of the Norwegian version of the Strengths and Difficulties Questionnaire in children aged 3–6 years
Authors: Aadland Katrine Nyvoll , Lervåg Arne , Ommundsen Yngvar , Aadland Eivind 
Published: December 2022

IntroductionThis study examined the structural validity of the teacher-report Strength and Difficulties Questionnaire (SDQ) in Norwegian preschoolers aged 3–6 years. We tested the original five-factor structure, the five-factor structure with two broader second-order factors, and a three-factor structure, all suggested in the literature. Since the positively worded items in SDQ have been shown to introduce noise, we also examined all three structures with a positive construal method factor for these items.MethodsPreschool teachers from 43 preschools completed the SDQ questionnaire for 1,142 children [48% girls, mean age 4.3 (SD 0.9) years]. Confirmatory factor analyses were used to estimate and compare the six models. Measurement invariance was tested across sex (multi-group approach) and age (multiple-indicator multiple-cause approach).ResultsThe original five-factor structure of SDQ was supported, where the model fit improved when including a method factor for positively worded items. Both models showed scalar invariance across sex and age. The second-order and the three-factor structures were not supported.ConclusionWe recommend using the original five-factor structure when using SDQ for both clinical and research purposes in young children and adding a method factor when using structural equation modeling.
The Concussion Challenge Assessment: Development and reliability of a novel gross motor assessment tool for paediatric concussion
Authors: Tanel Michelle R. , Gupta Christopher , Wilson Katherine E. , Murphy James , Wright F. Virginia , Reed Nick 
Published: December 2022

AimsThe aim of this study was to develop a gross motor performance clinical assessment tool, the Concussion Challenge Assessment (CCA), for paediatric concussion populations.MethodsAn expert panel evaluated tasks from the Acquired Brain Injury Challenge Assessment to determine relevant tasks for a paediatric concussion population. These tasks were administered to a convenience sample of 854 healthy youth. An analysis of the response options for each task, considering task difficulty, was performed. The test–retest reliability of each task was considered to finalise the tool.ResultsThe Acquired Brain Injury Challenge Assessment was reduced to six tasks (three coordination, two speed and agility, and one strength) to create the CCA. Population-specific 4-point response options were generated, which, upon examination of task difficulty, were revised as 5-point response sets to better capture performance differences. The test–retest reliability results led to acceptance of all six: three performance tasks and three exertion tasks.ConclusionThis development of the CCA is an important step in creating a gross motor performance assessment tool that can assist in the determination of when youth are able to safely return to activity following a concussion.
ISLAM MODERATE IN INDONESIA
Authors: Faqihuddin Ahmad 
Published: December 2022

Islam is a religion of peace, meaning that Islam does not justify violent practices, in a radical way to achieve a political goal or to maintain a belief that is considered sacred. Religion, which should be a guide for a friendly and tolerant life, has resulted in violence and terrorism. This means that there is a mistake in understanding and implementing fundamental religious teachings. Isn't it the opposite, Islam taught by the Prophet Muhammad SAW, in fact, proves to be a religion that upholds peace, compassion, and respects peace? The mission of Islam brought by the Prophet Muhammad SAW to mankind is peace (salam), this is why this religion is not called Mohammadanism, Arabism, or other isms, but this religion is called Islam which means safety, peace and peace, anyone who preaches Islam must have the principle of prioritizing peace not the other way around. Terrorism and religious radicalism are actually not only a problem of the perpetrators, and not the people who are victims of these actions, but terrorism and radicalism that must be paid attention to are problems of theological beliefs, meaning that the perpetrators can be arrested, imprisoned, and killed, but ideological beliefs and doctrines are not easily abolished. Therefore, it is necessary to discuss a friendly, tolerant, and soothing paradigm of Islamic understanding. This understanding is more suitable for Islamic moderation (Islam Wasathiyah).
Islam adalah agama damai, artinya Islam tidak membenarkan praktek kekerasan, dengan cara radikal untuk mencapai suatu tujuan politik atau untuk mempertahankan keyakinan yang dianggap suci, sangat tidak Islami. Agama yang seharusnya menjadi panduan hidup yang ramah dan toleran jusru menjadi timbulnya kekerasan dan terorisme. Hal ini berarti ada kesalahan dalam memahami dan mengimplementasi ajaran agama yang fundamental. Bukankah sebaliknya, Islam yang diajarkan oleh Nabi Muhammad SAW, justru membuktikan sebagai agama yang menjunjung tinggi perdamaian, kasih sayang, dan memahargai perdamaian? misi Islam yang dibawa oleh Nabi Muhammad SAW kepada ummat manusia adalah perdamaian (salam), dari sinilah mengapa agama ini tidak dinamakan Mohammadanisme, Arabisme, atau isme lain, akan tetapi agama ini dinamakan Islam yang berarti selamat, tentram dan damai, siapapun yang mendakwahkan Islam harus berprinsip mengutamakan perdamaian bukan sebaliknya. Terorisme dan radikalisme agama sebenarnya tidak hanya masalah pelakunya, dan bukan pula para orang-orang yang menjadi korban dari aksi tersebut, akan tetapi terorisme dan radikalisme yang harus di perhatikan adalah masalah keyakinan teologis, artinya pelaku bisa ditangkap, dipenjarakan, dan dibunuh, akan tetapi keyakinan dan doktrin ideologinya tidak mudah dihapuskan begitu saja. Oleh karena itu, perlu mewacanakan paradigma pemahaman keislaman yang ramah, toleran, dan menyejukkan. Pemahaman ini lebih cocok pada moderasi Islam (Islam Wasathiyah)
IMPLEMENTATION OF CASH WAQAF MANAGEMENT IN ASSALAM SOCIAL INSTITUTION, JAYAPURA CITY
Authors: Wahib Mohammad 
Published: December 2022

Cash waqf has the advantage of being easy to collect because it is not constrained by the complexity of immovable waqf objects such as land and buildings. People can donate their money directly or through the transfer line in a very easy, fast and practical way. One of the organizations actively managing cash waqf in Jayapura City, Papua Province is the Assalam Social Wallet (DSA). This study describes the implementation of cash waqf management in the Assalam Social Wallet in Jayapura City. This research uses descriptive qualitative type with data collection techniques using observation and interviews. From the results of this study it is known that the response of Muslims to the cash waqf program in the Social Institution of Assalam is quite good and significant. However, the empowerment programs run by Dompet Sosial Assalam are still limited and not yet optimal, not yet leading to dynamic, innovative and varied program forms. Cash waqf funds are only used to buy land designated for the location of the Assalam foundation education.
Wakaf tunai atau wakaf uang memiliki keunggulan, yaitu mudah dihimpun karena tidak terkendala dengan kerumitan benda wakaf yang tidak bergerak seperti tanah dan bangunan. Orang yang berwakaf dapat mewakafkan uangnya secara langsung atau lewat jalur transfer dengan cara yang sangat mudah, cepat dan praktis. Salah satu lembaga yang aktif mengelola wakaf tunai di Kota Jayapura Provinsi Papua adalah Dompet Sosial Assalam (DSA). Penelitian ini mendeskripsikan mengenai implementasi pengelolaan wakaf tunai di Dompet Sosial Assalam Kota Jayapura. Penelitian ini menggunakan jenis kualitatif deskriptif dengan teknik pengumpulan data menggunakan observasi dan wawancara. Dari hasil penelitian ini diketahui bahwa respon umat Islam terhadap program wakaf tunai di Dompet Sosial Assalam cukup baik dan signifikan. Namun program pemberdayaan yang dijalankan DSA masih terbatas dan belum maksimal, belum mengarah kepada bentuk program yang dinamis, inovatis dan variatif. Dana wakaf tunai hanya dimanfaatkan untuk membeli tanah yang diperuntukkan bagi lokasi pendidikan yayasan Assalam.
THE IMPORTANCE OF ARABIC LANGUAGE IN DA’WAH ACTIVITIES: A STUDY OF WOMEN IN DA’WAH
Authors: Yahaya Atiku Garba , Sani Fatima Muhammad 
Published: December 2022

This paper is on the importance of Arabic language and its usage in Da’awah activities by women in Da’awah in Nigeria. It also discussed how Arabic is used in Da’awah by Muslim women in Nigeria. It explained the mission and vision of Women in Da’awah (WID) and their various approaches to Da’awah that includes encouragement of the use and study of Arabic language. Likewise, the paper discusses the Da’awah activities of the Women in Da’awah and outline most the da’awah activities carried out by the organization. It also deliberates the importance of the use of the language for Da’awah purpose with evidence from the Qur’an and Sunnah. The paper adopted and used descriptive approach combined with content analysis approach. Arabic is a compulsory language. When Islam stretched and came into contact with other civilizations, Arabic acted as a bridge of scholarship through the movement of translation.
Makalah ini membahas tentang pentingnya bahasa Arab dan penggunaannya dalam kegiatan Dakwah oleh wanita dalam Dakwah di Nigeria. Dibahas pula bagaimana bahasa Arab digunakan dalam dakwah oleh wanita Muslim di Nigeria. Dijelaskan misi dan visi Women in Dakwah (WID) dan berbagai pendekatan mereka terhadap Dakwah yang mencakup dorongan penggunaan dan studi bahasa Arab. Demikian pula, makalah ini membahas kegiatan Dakwah para Wanita dalam Dakwah dan menguraikan sebagian besar kegiatan dakwah yang dilakukan oleh organisasi tersebut. Hal ini juga membahas pentingnya penggunaan bahasa untuk tujuan Dakwah dengan bukti dari Al-Qur'an dan Sunnah. Makalah ini mengadopsi dan menggunakan pendekatan deskriptif yang dikombinasikan dengan pendekatan analisis isi. Bahasa Arab adalah bahasa wajib. Ketika Islam merentang dan bersentuhan dengan peradaban lain, bahasa Arab berperan sebagai jembatan keilmuan melalui gerakan penerjemahan.