bluuebunny/crossref_metadata_2025_split huggingface dataset:
Das intimale Sarkom der Pulmonalarterie – Fallbericht einer seltenen Differenzialdiagnose der chronisch thromboembolischen pulmonalen Hypertonie
Authors: Pott Julian , Gräfin zu Reventlow Paulina , Simon Marcel , Steurer Stefan , Harbaum Lars , Henes Frank Oliver , Klose Hans 
Published: September 2022

ZusammenfassungDas Angiosarkom ist eine seltene, maligne Erkrankung, die von den Blutgefäßen ausgeht. Das pulmonale Angiosarkom kann sich diagnostisch initial wie eine chronisch thromboembolische pulmonale Hypertonie (CTEPH) darstellen. Die CTEPH ist eine Erhöhung des pulmonal-arteriellen Drucks und Widerstands als Folge einer persistierenden Obstruktion der Lungenstrombahn nach pulmonalen Thromboembolien trotz adäquater Antikoagulation.In unserer Ambulanz für pulmonale Hypertonie stellte sich ein 76-jähriger Patient mit
anamnestisch vor 7 Monaten erlittener subakuter, links zentraler Lungenarterienembolie (LAE)
vor, die seitdem mit Apixaban therapiert wurde. Bei persistierender Belastungsdyspnoe wurde
der Verdacht auf eine CTEPH gestellt und es erfolgte weitere Diagnostik. Passend zur CTEPH
zeigte sich spiroergometrisch eine ineffektive Ventilation und echokardiografisch eine
Rechtsherzbelastung. Eine Verlaufs-CT des Thorax ergab einen persistierenden und
größenkonstanten Füllungsdefekt der linken Pulmonalarterie mit szintigrafischem Nachweis einer
primären Perfusionsstörung des gesamten linken Lungenflügels. Mit dem Verdacht auf ein
malignes Geschehen veranlassten wir eine PET-CT, in welcher sich die Läsion der
Pulmonalarterie stoffwechselaktiv darstellte. Eine unter endobronchialer Ultraschallkontrolle
durchgeführte Punktion der Läsion ergab histologisch den Nachweis eines sarkomatoiden Tumors
mit Amplifikation des MDM2-Gens. Wir stellten die Diagnose eines Intimasarkoms der linken
Pulmonalarterie und führten den Patienten einer Pneumektomie zu.Die Intimasarkome der Pulmonalarterie sind selten und führen durch Wachstum und
Thrombusneigung zur Stenose des Gefäßes. Die damit einhergehende klinische und
echokardiografische Präsentation kann eine CTEPH imitieren und stellt somit eine wichtige
Differenzialdiagnose zu dieser dar. 2015 wurden weniger als 300 Fallberichte
beschrieben.Hinweise auf ein pulmonales Angiosarkom: Kontrastmittel aufnehmende, intraluminale
Gewebsformation mit Dilatation der Pulmonalarterie und Infiltration der Gefäßwand, erhöhte
Stoffwechselaktivität des Befundes in der FDG-PET CT, Größenprogredienz unter Antikoagulation,
anamnestisch keine stattgehabte LAE, B-Symptome.Die Diagnosesicherung erfolgt durch Biopsie. Das mediane Überleben wird mit 1,5–17 Monaten
beschrieben, welches mit therapeutischen Interventionen um einige Monate mit Symptomreduktion
verlängert werden kann. Als therapeutischer Standard gilt die Resektion des Tumors mit ggf.
Metastasenentfernung. Der Nutzen von Radio- und Chemotherapie ist Bestandteil aktueller
Forschung. Eine Behandlung ist in erfahrenen Zentren anzustreben und es bedarf weiterer
Forschung zur Verbesserung von Diagnostik und Therapie.
Antiphospholipid Antibodies in Pregnancy: Maternal and Neonatal Implications
Authors: Gris Jean-Christophe , Guillotin Florence , Chéa Mathias , Bourguignon Chloé , Nouvellon Éva , Bouvier Sylvie 
Published: September 2022

AbstractAntiphospholipid antibodies (aPL Abs) have long been associated with the occurrence of certain specific pregnancy morbidities, affecting both mother and fetus. Antithrombotic-based prophylactic regimens are the standard of care. Their intensity is modulated by the thrombotic history and has greatly improved the prognosis related to spontaneous morbidity. Observational studies show that this treatment is still associated with the persistence of excess of late-pregnancy placental diseases, calling for new or complementary developments, yet to be validated. Rigorous prospective multicentric validation of clinical and laboratory parameters capable of identifying those women and fetuses at a risk of pejorative evolution, thus early prognosis, is a priority issue. These will make it possible to develop customized treatments and test them. Furthermore, there are still concerns, particularly neurodevelopmental ones, about children born to aPL Ab-positive mothers, and clarification based on regular, more systematic evaluations is required. Even after pregnancy, women with a pure obstetrical antiphospholipid syndrome are at a greater risk of venous and arterial thrombosis over time, and prevention needs to be improved. These women also appear to develop more psychiatric and mood disorders. Central nervous system imaging using high-resolution techniques has shown subtle impairments in the white matter, associated with the most pathogenic aPL Abs and the clinical significance of this is under investigation. These mothers also seem to develop an excess of cancers. The systemic impact of aPL Abs is gradually being suspected, although this requires further evidence, and prevention should be envisaged.
Ritualized disbelief in Mexican Spanish talk-in-interaction
Authors: Carranza Ariel Vázquez 
Published: September 2022

Abstract
The present investigation is a conversation-analytic study that examines a particular type of informing sequence
where the new information is received with a turn displaying ritualized disbelief. In this paper, I analyze a range of ritualized
disbelief and news-confirmation turn designs in Mexican Spanish talk: I describe the trajectory that different ritualized
disbeliefs have, the composition of the disbelief they display, and how news-producers deal with ritualized disbelief turns. I
argue that a speaker’s knowledge about the matter at hand relates to the type of disbelief expressed in his or her disbelieving
turn; that is, the social actions involved in this type of sequences show a relationship between turn design, epistemics and
disbelief.
The effects of injury, contextual match factors and training load upon psychological wellbeing in English Premier League soccer players via season‐long tracking
Authors: Grimson Sophie , Brickley Gary , Smeeton Nicholas J. , Abbott Will , Brett Adam 
Published: September 2022

ABSTRACTThe study aimed to track psychological wellbeing (PWB) across two consecutive soccer seasons examining the effects of injury, illness, training load (TL) and contextual match factors (playing status, match selection and individual win rate). Furthermore, examine PWB prior to injury or illness event. Thirty‐two English Premier League (EPL) soccer players completed the “Warwick‐Edinburgh Mental Wellbeing Scale” every two weeks. No differences were found for group averaged PWB across the seasons (52.2 ± 0.3 vs. 51.8 ± 1.1) (p > 0.05). Previous 7‐day TL measured using GPS (session duration, total distance, explosive distance, low‐intensity distance, high‐speed distance (HSD) and sprint distance (SD)) were not related to current PWB (p > 0.05). Yet, previous 14‐day HSD (r (385) = −0.095) and 21‐day SD (r (385) = 0.100) were related to current PWB (p < 0.05). Only 100% (vs. 0%) win rate in the previous 14‐days to the questionnaire revealed a higher current PWB score (52.7 ± 4.7 vs. 50.9 ± 5.6 (p < 0.05)). PWB did not differ prior to an injury or illness event, when players were injured or had low contextual match factors at time of questionnaire or previous match, and the previous 7‐days (p > 0.05). In conclusion, PWB fluctuations across the season are associated with prior TL and multiple negative results. But prior PWB was not linked to injury or illness events. Implications for prioritising interventions to improve PWB during periods of chronic high intensity TLs and losing streaks, monitoring PWB, and use in injury and illness prediction are discussed.
Smooth coarse-graining and colored noise dynamics in stochastic inflation
Authors: Mahbub Rafid , De Aritra 
Published: September 2022

Abstract
We consider stochastic inflation coarse-grained using a general class of exponential filters. Such a coarse-graining prescription gives rise to inflaton-Langevin equations sourced by colored noise that is correlated in e-fold time. The dynamics are studied first in slow-roll for simple potentials using first-order perturbative, semi-analytical calculations which are later compared to numerical simulations. Subsequent calculations are performed using an exponentially correlated noise which appears as a leading order correction to the full slow-roll noise correlation functions of the type 〈ξ(N)ξ(N')〉(n) ∼ (cosh[n(N-N'+1])-1. We find that the power spectrum of curvature perturbations 𝒫
ζ
is suppressed at small e-folds, with the suppression controlled by n. Furthermore, we use the leading order, exponentially correlated noise and perform a first passage time analysis to compute the statistics of the stochastic e-fold distribution 𝒩 and derive an approximate expression for the mean number of e-folds 〈𝒩〉. Comparing analytical results with numerical simulations of the inflaton dynamics, we show that the leading order noise correlation function can be used as a very good approximation of the exact noise, the latter being more difficult to simulate.
Test of the statistical isotropy of the universe using gravitational waves
Authors: Galloni Giacomo , Bartolo Nicola , Matarrese Sabino , Migliaccio Marina , Ricciardone Angelo , Vittorio Nicola 
Published: September 2022

AbstractSince WMAP and Planck some anomalous features appeared in the Cosmic Microwave Background (CMB) large-angle anisotropy, the so-called anomalies. One of these is the hemispherical power asymmetry, i.e. a difference in the average power on the two hemispheres centered around (l,b) = (221, -20), which shows a relatively high level of significance. Such an anomaly could be the signature of a departure from statistical isotropy on large scales. Here we investigate the physical origin of this anomaly using the Cosmological Gravitational Wave Background (CGWB) detectable by future GW detectors. Indeed, the CGWB offers a unique window to explore the early universe and we show that it can be used in combination with CMB data to shed light on the statistical isotropy of our universe. Specifically, we study the evolution of gravitons in the presence of a modulating field in the scalar gravitational potentials accounting for the hemispherical power asymmetry and we infer the amplitude of this modulating field through a minimal variance estimator exploiting both constrained and unconstrained realizations of the CGWB. We show that the addition of the CGWB will allow an improvement in the assessment of the physical origin of the CMB power asymmetry. Accounting for the expected performances of LISA and BBO, we also show that the latter is expected to be signal-dominated on large-scales, proving that the CGWB could be the keystone to assess the significance of this anomaly.
Estimating the impact of foregrounds on the future detection of Rayleigh scattering
Authors: Zhu Yijie , Beringue Benjamin , Choi Steve K. , Battaglia Nicholas , Meerburg P. Daniel , Meyers Joel 
Published: September 2022

Abstract
Rayleigh scattering of the cosmic microwave background (CMB) by neutral hydrogen shortly after recombination leaves frequency-dependent imprints on intensity and polarization fluctuations. High signal-to-noise observations of CMB Rayleigh scattering would provide additional insight into the physics of recombination, including greater constraining power for parameters like the primordial helium fraction, the light relic density, and the sum of neutrino masses. However, such a measurement of CMB Rayleigh scattering is challenging due to the presence of astrophysical foregrounds, which are more intense at the high frequencies, where the effects of Rayleigh scattering are most prominent. Here we forecast the detectability of CMB Rayleigh scattering including foreground removal using blind internal linear combination methods for a set of near-future surveys. We show that atmospheric effects for ground-based observatories and astrophysical foregrounds pose a significant hindrance to detecting CMB Rayleigh scattering with experiments planned for this decade, though a high-significance measurement should be possible with a future CMB satellite.
Quercetin improves rapid endothelialization and inflammatory microenvironment in electrospun vascular grafts
Authors: Gui Yuan , Qin Kang , Zhang Ye , Bian Xiangyu , Wang Zhiguang , Han Dianpeng , Peng Yuan , Yan Hongyuan , Gao Zhixian 
Published: September 2022

Abstract
There is a great need for small diameter vascular grafts among patients with cardiovascular diseases annually. However, continuous foreign body reactions and fibrosis capsules brought by biomaterials are both prone to poor vascular tissue regeneration. To address this problem, we fabricated a polycaprolactone (PCL) vascular graft incorporated with quercetin (PCL/QCT graft) in this study. In vitro cell assay showed that quercetin reduced the expressions of pro-inflammatory genes of macrophages while increased the expressions of anti-inflammatory genes. Furthermore, in vivo implantation was performed in a rat abdominal aorta replacement model. Upon implantation, the grafts exhibited sustained quercetin release and effectively enhanced the regeneration of vascular tissue. The results revealed that quercetin improved endothelial layer formation along the lumen of the vascular grafts at four weeks. Furthermore, the thickness of vascular smooth muscle layers significantly increased in PCL/QCT group compared with PCL group. More importantly, the presence of quercetin stimulated the infiltration of a large amount of M2 phenotype macrophages into the grafts. Collectively, the above data reinforced our hypothesis that the incorporation of quercetin may be in favor of modulating the inflammatory microenvironment and improving vascular tissue regeneration and remodeling in vascular grafts.
Impacts and synergies of weather index insurance and microcredit in rural areas: a systematic review
Authors: Lu Yu , Yu Lu , Li Wen-Jun , Aleksandrova Mariya 
Published: September 2022

Abstract
Weather constitutes a major source of risks facing households in rural areas, which are being amplified under climate change. In this context, two main rural financial services, weather index insurance and microcredit, have been increasingly adopted by farmers worldwide. However, the understanding of the socioeconomic and ecological impacts of these rural finance schemes, including potential maladaptive outcomes, remains ambiguous. We review the recent literature on weather index insurance and microcredit for farmers and find that both rural financial services have positive economic impacts, though benefits to the poorest populations remain controversial. Moreover, their impacts on the ecological systems are less studied and are found to be mainly negative. In addition, considering that both financial instruments have strengths and limitations, we argue that combination schemes (e.g. a hybrid product) may generate positive synergistic effects on building socioeconomic resilience to climate risks in agricultural regions. However, this may also add new economic risk to local financial institutions. This comprehensive review provides a reference for the potential benefits and risks of agricultural finance innovations. Further studies on the ecological impacts of rural financial services and the synergistic effects of the combination on socioeconomic and ecosystem resilience in rural contexts are needed to fill the current research gap.
The nitrogen footprint of Swedish food consumption
Authors: Einarsson Rasmus , Henriksson Maria , Hoffmann Markus , Cederberg Christel 
Published: September 2022

Abstract
Food systems are major drivers of environmental and health impacts. While the emissions and other pressures causing these impacts mainly occur in primary agricultural production, the deeper causes and much of the mitigation potential are distributed throughout food systems, including dietary choices and multiple inefficiencies in the whole chain from agricultural production to consumption and waste management. An environmental indicator based on this systems perspective is the nitrogen (N) footprint, defined as the emissions of reactive N due to the consumption of an individual or other entity. Here, we present a method to estimate the N footprint of Swedish food consumption, using a detailed inventory of agricultural production, food and feed processing, food waste, waste management, and wastewater treatment. Limitations of data sources and methods are discussed in detail. The estimated Swedish food N footprint is 12.1 kg N capita−1 yr−1, of which 42% is emitted in Swedish production, 38% in production abroad, 1% in consumer waste management, and 19% in wastewater treatment. Animal food products account for 81% of the food N footprint and 70% of the protein intake. Average protein intake exceeds nutritional requirements by about 60%, which suggests that at least 35% reduction of food-related reactive N emissions could be achieved through dietary change. Of the apparent food N consumption (6.9 kg N capita−1 yr−1), about 22% is food waste N (1.5 kg N capita−1 yr−1). We estimate that 76% of food waste N is unavoidable (bones and other parts not commonly eaten). Avoidable food waste is about 7% of the edible food supply, implying that a hypothetical complete elimination of food waste would reduce emissions by about 7%. In summary, we present a detailed method, discuss its limitations, and demonstrate possible uses of the N footprint as a complement to existing territorial and sectoral environmental indicators.
Something in the wind: the influence of wind speed and direction on African lion movement behavior
Authors: Wijers Matthew , Trethowan Paul , du Preez Byron , Loveridge Andrew J , Markham Andrew , Macdonald David W , Montgomery Robert A 
Published: September 2022

Abstract
Olfaction is a key sense, enabling animals to locate forage, select mates, navigate their environment, and avoid predation. Wind is an important abiotic factor that modulates the strength of olfactory information detected by animals. In theory, when airflow is unidirectional, an animal can increase odor detection probability and maximize the amount of olfactory information gained by moving crosswind. Given energetic costs inherent to activity and locomotion, behavioral search strategies that optimize the benefit-cost ratio should be advantageous. We tested whether African lions (Panthera leo) modify their movement directionality and distance according to wind speed and direction during hours of darkness when they are most active. We tracked 29 lions in southern Zimbabwe using GPS collars and deployed a weather station to collect detailed abiotic data. We found that when wind speeds increased lions were more likely to move crosswind. We also found that female lions, which tend to hunt more often than males, traveled farther when wind speeds were stronger. The results of our analysis suggest that lions adjust their movement behavior according to wind speed and direction. We inferred that this was a behavioral decision to maximize the amount of olfactory information gained per unit of energy spent. Our findings not only offer one of the first detailed insights on large carnivore anemotaxis (movement direction relative to wind) but also make an important contribution towards understanding the influence of wind on predator ecology in general which remains understudied to date.
Experience Using Adjuvant Bacteriophage Therapy for the Treatment of 10 Recalcitrant Periprosthetic Joint Infections: A Case Series
Authors: Doub James B , Johnson Aaron J , Nandi Sumon , Ng Vincent , Manson Theodore , Lee Myounghee , Chan Benjamin 
Published: September 2022

Abstract
Periprosthetic joint infections are a devastating complication of joint replacement surgery. One novel therapeutic that has potential to change the current treatment paradigm is bacteriophage therapy. Herein, we discuss our experiences with bacteriophage therapy for 10 recalcitrant periprosthetic joint infections and review the treatment protocols utilized to achieve successful outcomes.
Intergovernmental dynamics in responding to COVID-19 in English and Australian cities
Authors: Broadhurst Kate , Steane Edward , Mykhnenko Vlad , Gray Nicholas 
Published: September 2022

AbstractThis comparative study, conducted at the height of the COVID-19 pandemic, explores how the contrasting governance systems in Australia and England responded to complex and rapidly evolving problems presented by the crisis. Comparing how national and local governments worked together and alongside other forms of subnational governance, the findings highlight the efficacy of multi-scalar governance arrangement in Australia over the fragmented, overly-centralised and inconsistent arrangements in England. As nations plan their recovery paths from the economic and social challenges of the crisis, the findings encourage a reset of spatial policy towards one that values and resources greater decentralisation and place-based recovery.
When the personal becomes political: Rethinking legal fatherhood
Authors: Margaria Alice 
Published: September 2022

Abstract
Inspired by my personal experience as a working mother during the pandemic, this contribution reflects on the urgent need, and possible ways, to rethink legal fatherhood. If the aim is to make fathers (more) active carers, making family-leave policies more assertive in encouraging fathers’ uptake is certainly an important first step towards bringing men into the care frame. Yet, to counter the multiple negative effects of the pandemic on women, legal fatherhood must undergo a structural rethinking, which extends to legal regulation more broadly. A legal venue where this rethinking is long overdue is filiation law, whose rules function as channels through which notions and arrangements of (child)care are created and can, therefore, also be recreated. Driven by the desire to promote a substantive vision of equality, this article argues for a relational rethinking of legal fatherhood, which is mindful of the interconnectedness between the lives of women, men, and children, and places care at its core.
Liking versus commenting on online news: effects of expression affordances on political attitudes
Authors: Wang Jinping , Sundar S Shyam 
Published: September 2022

AbstractBy performing actions such as “liking” a post, commenting on it, or sharing it with others, we are constantly expressing our opinions about ongoing news and public affairs on online media platforms. How do these acts of expression affect our feelings and opinions? We address this question from an “affordance” perspective, focusing on the effects of both the presence of the expression affordance (cue effects) and users’ actual engagement with it (action effects). We conducted an online experiment (N = 368) on a news website with thumbs-up/down and/or commenting as low-effort and high-effort expression affordances, respectively. Data revealed that the low-effort affordance led to more affective polarization while the high-effort affordance promoted increased interest in deliberation. Merely presenting a commenting cue mitigated affective polarization by increasing perceived interactivity. However, when users engaged the affordance by providing comments, it tended to reinforce pre-existing opinions. These findings have theoretical and practical implications.