bluuebunny/crossref_metadata_2025_split huggingface dataset:
How eye tracking may advance the field of mathematics education: a commentary on the ESM Special Issue on eye-tracking research in mathematics education
Authors: Bikner-Ahsbahs Angelika 
Published: February 2025

Abstract
Eye-tracking technologies are increasingly being used for empirical research in mathematics education. However, we do not yet know how they are influencing the field. In this commentary paper, the articles in the Special Issue on research with eye-tracking are examined to reconstruct how they have advanced the field. To address this research aim, the construct of research praxeology is used. Based on the components of a praxeology, four types of progress are identified and characterized: Theoretical progress within a theoretical research program, methodological progress through the development of a research instrument, progress through the establishment of new types of research questions and aims, which address new topics, and progress in relation to a research technique. These types of progress show that the articles on eye tracking may advance the field by consolidating and redirecting previous research, pointing to new lines of research and providing new kinds of tasks. Knowledge of these types of progress can help researchers to shape, situate, and critically reflect on their publications.
Growth rate comparison of three Kappaphycus alvarezii colour strains cultivated using tubular netting and tie-tie methods in the waters of Ecuador
Authors: Cáceres-Farias Lenin , Montúfar-Romero Milton , Lodeiros César , Espinoza-Vera María Mercedes , Cáceres-Farias Lorena Belén , Avendaño Ulises , Ruiz-Chóez Walter , Alfaro-Núñez Alonzo 
Published: February 2025

Abstract

Kappaphycus alvarezii is widely cultivated in tropical regions, with its growth influenced by cultivation techniques. Despite extensive global studies, there is a knowledge gap in Ecuador regarding the performance of different strains and systems under local specific conditions. The growth performance of K. alvarezii strains (green, brown, and red) cultivated in Ecuador using “tubular nets” and “tie-tie systems” was evaluated. Fifteen thalli from each strain were grown for 70 days, with daily measurements of water temperature, salinity, dissolved oxygen, turbidity, and nutrient levels. No significant differences were detected between the systems, and their DGR growth rates were high for algae culture development (4.0 ± 0.92% day⁻1 in the tie-tie and 3.8 ± 0.81% day⁻1 in the tubular net) demonstrating their suitability for commercial cultivation. All strains exhibited DGR > 3%, with the green strain particularly excelling in the tubular system (6.1 ± 5.54% day⁻1). The local environmental conditions were found to be favourable for macroalgal growth, with a particularly strong positive correlation with temperature. The results show that both cultivation systems are viable for the commercial production of K. alvarezii, establishing a foundation for future applications in local aquaculture and highlighting the adaptability of the evaluated strains to Ecuador's environmental conditions.
The minimum orientable genus of the repeated Cartesian product of graphs
Authors: Galea Marietta , Gauci John Baptist 
Published: February 2025

Abstract
Determining the minimum genus of a graph is a fundamental optimisation problem in the study of network design and implementation as it gives a measure of non-planarity of graphs. In this paper, we are concerned with determining the smallest value of g such that a given graph G has an embedding on the orientable surface of genus g. In particular, we consider the Cartesian product of graphs since this is a well studied graph operation which is often used for modeling interconnection networks. The s-cube

$$Q_i^{(s)}$$

Q
i

(
s
)

is obtained by taking the repeated Cartesian product of i complete bipartite graphs

$$K_{s,s}$$

K

s
,
s

. We determine the genus of the Cartesian product of the 2r-cube with the repeated Cartesian product of cycles and of the Cartesian product of the 2r-cube with the repeated Cartesian product of paths.
Spiritual Well-Being and Treatment Adherence in Patients with Type 2 Diabetes in Turkey
Authors: Erden Melikoğlu Seçil , Köktürk Dalcali Berna , Güngörmüş Esra , Kaya Hatice 
Published: February 2025

Abstract
This study aimed to identify the correlation between treatment adherence and spiritual well-being in patients with Type 2 Diabetes. A descriptive and correlational design was used. The study consisted of 203 patients. The data were collected through a patient information form, The Scale for Compliance to the Treatment in Type 2 Diabetes Mellitus and the FACIT-Sp-12 and analyzed by using descriptive and Pearson’s Correlation analysis. A correlation was found between patients treatment adherence and their peace, faith, and meaning sub-dimensions of the FACIT Sp-12. This study shows a need for interventions for patients with Type 2 diabetes to increase their spiritual well-being and, therefore, their treatment adherence. For this reason, individuals’ needs should be met with a holistic approach by integrating spiritual care into nursing care practices.
Probabilistic numerical simulation of morphology development from non-isothermal calorimetric crystallization curves
Authors: Lelik Alíz , Bubenkó Lilla , Koncz Medárd , Molnár János , Sepsi Örs , Menyhárd Alfréd 
Published: February 2025

Abstract
This work introduces a probabilistic numerical simulation method to describe or predict the spherulitic morphology of semicrystalline polymer formed during non-isothermal crystallization process. The numerical simulation is based on the general crystallization theory, which consists of random nucleation and subsequent growth of supermolecular formations. The model is capable for prediction of morphology from the conversion curve of crystallization recorded by calorimetry during crystallization at a constant cooling rate. Samples made of polypropylene nucleated by different nucleating agents were used as a model material for testing the simulation approach. The results indicated that valuable structural information can be predicted from the conversion curve, like nucleus density, average spherulite size and size distribution as well. In addition, the simulation method also capable to predict the mechanism of nucleation during the crystallization process, namely, whether the number of nuclei is constant or continuously changing. The results also indicated that nucleus density increases significantly as a consequence of heterogeneous nucleation, which indicates that the simulation results in realistic and reliable structural data both in nucleated and non-nucleated samples.
Strategies for Promoting Doula Inclusivity in the Labor and Delivery Setting
Authors: Perkins Holly DeBernard , Isaacs Christine 
Published: February 2025

Abstract

Purpose
Our facility aimed to establish a standardized process to guide healthcare team members to incorporate doulas in the labor and delivery setting while meeting regulatory and safety requirements and promoting operational transparency.

Description
Doulas provide emotional, physical, and educational support to patients and families throughout the pregnancy, birth, and postpartum journey. Doula care has been identified with improved maternal and neonatal birth outcomes, as well as improved perceptions of the birthing process.

Assessment
Our facility lacked a standard operating procedure for successfully incorporating doulas into the healthcare team.

Conclusion
We developed strategies to promote doula inclusivity in our labor and delivery environment with safety and quality at the core of our focus.
Patient and hospital staff perspectives on introducing pharmacist-led medication reviews at an orthopedic ward: a mixed methods pilot study
Authors: Revell Joo Hanne Poulsen , Schlünsen Maja , Kandasamy Abisha , Meijers Annette , Eggers Jens , Kjeldsen Lene Juel 
Published: February 2025

Abstract

Background
Multi-morbidity is associated with multiple medication use, which potentially increases the risk of adverse drug events. Pharmacist-led medication reviews have been introduced to meet these challenges.

Aim
To evaluate the implementation of pharmacist-led medication reviews for older patients admitted to an orthopedic ward in terms of quality and safety from the perspectives of patients, hospital-based physicians, nurses, and healthcare assistants.

Method
Patients (n=11) were interviewed, with the interviews having a reflexive thematic analysis using the hermeneutic approach, while healthcare-professionals’ (HCPs) (n=26) perspectives on pharmacist-led medication reviews were assessed using questionnaires.

Results
The qualitative patient interviews revealed four themes: (1) Positive perception of pharmacists’ medication communication, (2) Mixed perceptions of a medication review, (3) Satisfaction with the general outcome of the medication review, and (4) Safety perception with medication treatment. Twenty-six HCPs completed the questionnaire (response rate 48%) with a distribution of 10 hospital-based physicians (38%), eight nurses (31%), and eight healthcare assistants (31%). Almost 85% of the HCPs (n = 22) were familiar with the pharmacist conducting medication reviews. More than 70% of the HCPs reported that pharmacist-led medication reviews contributed to increased quality of admitted patients’ medication use.

Conclusion
High levels of satisfaction with the outcomes of the medication reviews—particularly regarding quality, patient safety, and their overall positive impact on the ward—indicate that both patients and HCPs perceived the service as highly valuable in supporting patient care throughout the medication process.
Life Satisfaction and Internet Use in Later Life in Italy: The Role of Online Activities and Living Arrangements
Authors: Furlan Claudia , Meggiolaro Silvia 
Published: February 2025

Abstract
This study aimed to provide new insights into the role of internet use in the life satisfaction of older people in Italy, considering, in detail, the types of their online activities and the potential differences between these activities according to the old people’s genders and living arrangements. The data came from the survey Aspects of Daily Life conducted by the Italian National Institute of Statistics in 2021. The results of the logistic regression models used suggest that some online activities have associations with life satisfaction that vary according to gender and living arrangement. In particular, men living alone seem to benefit from voice and video calls, and men living with others, from messaging. On the other hand, for women living alone, online activities do not seem to be significantly associated with life satisfaction, but for women living with others, voice and video calls seem to be positively related to life satisfaction. Thus, not all online activities can be considered significant tools of empowerment for older adults. Specifically, internet use may have a beneficial effect among older Italians (excluding women living alone) when it is used to maintain or reinforce a real social network that is already present.
Happiness and productivity: a research synthesis using an online findings archive
Authors: Fang Yizhen , Veenhoven Ruut , Burger Martijn J. 
Published: February 2025

Abstract
The ‘happy productive worker’ thesis (HPW) holds that the happiness of workers has a positive impact on their productivity. In this study, we take stock of the research findings about the relationship between happiness on the productivity of workers that have been collected in the World Database of Happiness. We considered both objective and subjective productivity measures. In total, we drew on 33 studies that yielded 197 correlational findings over 27 countries and regions. The following questions were addressed: (1) Does happiness have a positive association with productivity? (2) Does the positive association between happiness and productivity differ across sectors and occupations? (3) Which component of happiness relates most to a productive workplace: how well a worker feels most of the time (the affective component) or the degree to which a worker feels able to get what they want from life (the cognitive or evaluative component)? (4) To what extent can we speak of a causal effect of happiness on productivity at work? Overall, the findings provide evidence of a positive relationship between happiness and productivity. The association between happiness and productivity at work differ across occupations and sectors and seems to be particularly strong for the affective component of happiness (how well a worker feels most of the time). More comparison studies are necessary to examine the relative importance of the affective and cognitive component. A causal effect of happiness on productivity is likely to exist but empirical evidence is thin on the ground.
Comparison of physiological and physical demands between small-sided games and official matches in youth football players
Authors: Carril-Valdó Jorge J. , Ferrandis Jordi , Claver Fernando , Gil-Arias Alexander , González-Rodenas Joaquín 
Published: February 2025

Abstract

Purpose
This study aimed to compare the physiological and physical demands between two spatial formats of small-sided games (SSGs) and competitive matches in youth football players.

Method
Fifteen U14 sub-elite players were monitored using WIMU PRO™ devices (Huddle, USA) during competition and training. The training involved two 7 vs. 7 SSGs formats: small (SSGs-S; 132 m2 per player) and large (SSGs-L; 232 m2 per player). Variables such as relative maximum heart rate (HRMAX), total distance (TD), high-intensity running distance (HIRD), high-metabolic load distance (HMLD), maximum speed (SpeedMAX), average speed (SpeedAVG), and acceleration distance were evaluated.

Results
Repeated measures ANOVA revealed that players covered more TD, HIRD, and HMLD per minute during SSGs-L than in both competition and SSGs-S (p < .01; effect size [ES] = .81, .76, .73, respectively). Competitive matches showed higher SpeedMAX (p < .01; ES = .93) and SpeedAVG (p < .01; ES = .84) compared to SSGs. Both SSGs formats exhibited higher distances covered in accelerations (> 2 m/s2) than competitive matches (p < .01; ES = .86).

Conclusion
This study emphasizes the importance for fitness coaches to manipulate pitch size during SSGs to replicate, increase or decrease physiological and physical demands relative to competitive conditions.
Recent aspects of chemical enhanced oil recovery
Authors: Nagy Roland , Hartyányi Máté , Bejczi Rebeka , Bartha László , Puskás Sándor 
Published: February 2025

Abstract
The majority of the world’s current crude oil production comes from mature fields. In addition, the rate of replenishment of reserves produced by new discoveries has been decreasing steadily over the past decades. This article provides a comprehensive overview of the status of CEOR and the opportunities for increasing ultimate recovery factors in reservoirs ranging from extra heavy oil to gas condensate. The review specifically discusses the status of CEOR and the chemicals used. Our aim in this work was to present both traditional and newer chemicals used. The relevant pilot tests were collected, because the literature on these is scarce. The published pilot projects are for the period after 2018. This article also describes chemical EOR opportunities, which also represent new CEOR drivers and challenges, especially economics. Recent CEOR technological developments and future CEOR opportunities will be discussed. State-of-the-art CEOR technologies were presented. This review provides comprehensive information on chemical EOR applications in sustainable energy production. After studying the professional publications, it is clear that CEOR technologies will be increasingly needed in the future.
Immunomodulatory Significance of Mast Cell Exosomes (MC-EXOs) in Immune Response Coordination
Authors: Elieh-Ali-Komi Daniel , Shafaghat Farzaneh , Alipoor Shamila D. , Kazemi Tohid , Atiakshin Dmitrii , Pyatilova Polina , Maurer Marcus 
Published: February 2025

Abstract
Mast cells (MCs) communicate with other cells by direct cell-to-cell interaction, secreting mediators, and releasing exosomes (EXOs). MC-exosomes (MC-EXOs) contain proteins, lipids, mRNAs, and noncoding RNAs (ncRNAs), exhibit typical EXO markers such as heat shock proteins, tetraspanins, tumor susceptibility gene 101 protein (TSG101), and ALG-2-interacting protein X (ALIX), and are released constitutively or following MC degranulation. MC-EXOs also have signature MC markers like FcεRI and KIT (CD117), which allows for their identification and comparison with other EXO populations. Following their release, MC-EXOs may interact with the recipient cell(s) directly or be internalized and then release their protein and nucleic acid content. This may contribute to the regulation of immune responses and other biological processes and reprogramming of recipient cells. MC-EXO proteins may integrate and become a functional part of the recipient cell membrane. The mRNA transferred by MC-EXOs is functional and the transfer of exosomal RNA to other MCs results in the expression of donor MC proteins in the recipient MCs. Moreover, MCs may function as the recipients of EXOs that are released by other non-immune and immune cells, altering the secretome of MCs. In this review, we focus on how MC-EXOs modulate the biology of other cells and vice versa; and we highlight the role of MC-EXOs in the pathogenesis of allergic and non-allergic diseases.
What will justice in the European Union look like in 10 years, and how could the legal professions in the EU innovate together?
Authors: Depasquale Francesco 
Published: February 2025

Abstract
The future of justice will certainly be characterised by the advance and development of artificial intelligence and the ability of the legal world to adapt and adopt such new technologies so as to provide a more efficient and effective outcome to the end users. Collaboration and co-operation among the various stakeholders, both locally and internationally, as well as the sharing of good practices, will certainly ensure that any developments retain, at its core, the fundamental principles of human rights, which are at the core of a just and unbiased judicial process. The article attempts to address these issues, making reference to documents and resources of the CEPEJ.
Spatiotemporal investigation of scaling properties of precipitation using high resolution data
Authors: Ozger Mehmet 
Published: February 2025

Abstract
Natural systems, driven by complex processes, exhibit variations in their behavior across different time scales. These variations often follow power-law relationships, providing valuable insights into the underlying physical mechanisms. This study investigates the scaling and multifractal behavior of precipitation using high-resolution (1-minute) data from nine stations across diverse climatic zones in Istanbul. By using high-resolution data, the study investigates precipitation scaling at sub-daily time scales, which is crucial for understanding short-duration rainfall events and their potential impacts on urban areas like Istanbul. The research employs a combination of spectral scaling, detrended fluctuation analysis (DFA), wavelet variance, and multifractal analysis to examine precipitation scaling. The calculated scaling exponents were then compared to identify potential interdependencies. Notably, the multifractal analysis revealed an apparent multifractal character in the precipitation data for all stations. The results of the study indicate that the precipitation data exhibits multifractal characteristics at all stations, with spectral scaling exponents ranging from 0.58 to 0.98 and Hölder exponents tending towards 0.5, indicating weak positive serial correlations. The findings of this research have important implications for various hydrological applications, including the development of intensity-duration-frequency (IDF) curves and the evaluation of global circulation models (GCMs).
Genetically predicted inflammatory proteins mediate the association between gut microbiota and renal cell carcinoma
Authors: Zou Xinyun , Li Dong , Zhang Ling , Shen Jinlan 
Published: February 2025

Abstract

Background
Studies have indicated a potential relationship between gut microbiota and renal cell carcinoma. However, the causal relationship between various types of gut microbiota and renal cell carcinoma, as well as the role of inflammatory protein as mediators, remains unclear.

Methods
This study aimed to identify the relationship between gut microbiota, inflammatory protein, and renal cell cancer through a large-scale genome-wide association study (GWAS) utilizing pooled data. We employed Mendelian randomization (MR) to investigate the causal relationship among these variables. Inverse variance weighting (IVW) was utilized as the primary statistical method. Furthermore, we examined the mediating role of inflammatory protein in the pathway through which gut microbiota influences the development of renal cell cancer.

Results
The analysis revealed 12 positive causal relationships and 15 negative causal relationships between the genetic liability of gut microbiota and renal cell cancer. Furthermore, there were three positive causal relationships and one negative causal relationship between inflammatory proteins and renal cell cancer. There were two axes of relationships in which gut microbiota promote the development of renal cell cancer. through inflammatory proteins acting as mediators.

Conclusions
Gut microbiota and inflammatory protein were causally related to renal cell cancer, and inflammatory protein were intermediary factors in the pathway between gut microbiota and renal cell cancer.
The other side of variant transthyretin amyloidosis with polyneuropathy: psychosocial experience of members of Portuguese families with late onset of the disease
Authors: Pereira José D. , Santos Andreia , Cisneros-Barroso Eugenia , Anan Intissar , Lemos Marina S. , Paneque Milena 
Published: February 2025

Abstract
This study is the first to explore the psychosocial experience of members of Portuguese families with late-onset variant transthyretin amyloidosis with polyneuropathy (A-ATTRv-PN). Based on a constructivist worldview, this phenomenological investigation followed a qualitative approach by conducting eight interviews and analyzing qualitative data. The main results suggest that the psychosocial experience of the members of families interviewed is marked by: (a) a delayed awareness of the family disease (viz., in adulthood), (b) psychosocial impacts (viz., emotional and other impacts related to work, parenting, caregiving) experienced and anticipated in an adult phase of the life cycle, and (c) the use of approach strategies (e.g., seeking information about A-ATTRv-PN and seeking social support) and/or avoidance strategies (e.g., avoiding seeking information and talking to others about the condition) with a view to accommodating A-ATTRv-PN in personal and family life. These results differ from the life trajectories of members of Portuguese families with A-ATTRv-PN described previously and extend previous scientific evidence on the psychosocial experience of members of families where the disease typically appears late, contributing to further study on this topic and to the optimization of genetic counseling practices and health policies that respond to the psychosocial needs of members of Portuguese families with late onset of the condition. Future studies should continue to deepen our understanding of the psychosocial experience of this population to improve the clinical response provided to patients, families, and caregivers.