bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety and Immunogenicity of Inactivated and Recombinant Protein SARS-CoV-2 Vaccines in Patients With Thyroid Cancer
Authors: Han Yuling , Yang Jiaxin , He Danshuang , Feng Yang , Liu Xiaoman , Min Yu , Fan Shenghao , Yin Guobing , Hu Daixing 
Published: May 2022

BackgroundThis study aimed at assessing the safety and immunogenicity of SARS-CoV-2 vaccines in patients with thyroid cancer.MethodsThis observational study included thyroid cancer patients between April 1, 2021, and November 31, 2021, in the Second Affiliated Hospital of Chongqing Medical University. All participants received at least one dose of the SARS-CoV-2 vaccine. SARS-CoV-2 IgG was tested, and the interval time between the last dose and humoral response test ranged from &lt;1 to 8 months. The complications after SARS-CoV-2 vaccines were recorded.ResultsA total of 115 participants at least received one dose of SARS-CoV-2 vaccines with a 67.0% IgG-positive rate. Among them, 98 cases had completed vaccination, and the positivity of SARS-CoV-2 IgG antibodies was 96% (24/25) with three doses of ZF2001. SARS-CoV-2 IgG antibodies’ positivity was 63.0% (46/73) of two doses of CoronaVac or BBIBP-CorV vaccine. Additionally, after 4 months of the last-dose vaccination, the IgG-positive rate (31.6%, 6/19) significantly decreased in thyroid cancer patients. The IgG-positive rate (81.0%, 64/79) was satisfactory within 3 months of the last-dose vaccination. Ten (10.2%) patients had side effects after SARS-CoV-2 vaccination. Among them, two (2.0%) patients had a fever, five (5.1%) patients had injection site pain, one (1.0%) patient felt dizzy, and one patient felt dizzy and had injection site pain at the same time.ConclusionSARS-CoV-2 vaccines (CoronaVac, BBIBP-CorV, and ZF2001) are safe in thyroid cancer patients. The regression time of SARS-CoV-2 IgG is significantly shorter in thyroid cancer patients than in healthy adults. Therefore, a booster vaccination dose may be earlier than the systematic strategy for thyroid cancer patients.
Immunocytes Rapid Responses Post-ischemic Stroke in Peripheral Blood in Patients With Different Ages
Authors: Zhang Haiyue , Guan Jingwei , Lee Hangil , Wu Chuanjie , Dong Kai , Liu Zongjian , Cui Lili , Song Haiqing , Ding Yuchuan , Meng Ran 
Published: May 2022

ObjectivesTo explore the alterations in immune cell composition in peripheral blood in patients with acute ischemic stroke (AIS) based on their age group.MethodsPatients with imaging confirmed AIS were enrolled from April 2019 to January 2020 and were divided into three groups according to their ages: &lt;55 years (group-A), 55–65 years (group-B), and &gt;65 years (group-C). Blood samples were collected immediately when the patients were admitted to our ward prior to any intervention. Flow cytometry was used to analyze immune cell composition in peripheral blood.ResultsA total of 41 eligible patients were included for final analysis. Among the three groups, the proportions of CD56+ CD16dim NK cells were least to greatest in group-B, group-A, then group-C, respectively. With increasing age, there was a decrease in the proportion of CD3+ T-cells (group-A vs. group-C, P = 0.016) and CD3+CD4+ T-cells (group-C vs. group-A, P = 0.008; group-C vs. group-B P = 0.026). Meanwhile, no significant differences in proportions of monocytes and B cells were observed.ConclusionsThe compositions of immune cells in peripheral blood of AIS patients were distinct when divided by age groups. Differences in immune cell ratios may affect clinical outcomes and foreshadows possible need for customized treatment of AIS in different age groups.
Prognostic Factors and Treatment Strategies for Elderly Patients with Malignant Meningioma: A SEER Population-Based Study
Authors: Feng Songshan , Li Jing , Fan Fan , Wang Zeyu , Zhang Qian , Zhang Hao , Dai Ziyu , Zhang Xun , Luo Peng , Liu Zaoqu , Zhang Jian , Liu Zhuoyi , Cheng Quan 
Published: May 2022

ObjectiveMalignant meningioma (MM) is a relatively rare disease with poor survival. Few studies had focused on MM in the elderly population. This study aims to explore the prognostic factors and optimal therapeutic strategy in elderly patients with MM.MethodsWe took advantage of the Surveillance, Epidemiology, and End Results (SEER) database to include 275 adult patients with histologically confirmed MM between 2011 and 2018. The Kaplan–Meier curves were plotted by different covariates to reveal the survival probability. Univariate and multivariable Cox proportional hazard regression analyses were applied to identify prognostic factors for cancer-specific survival (CSS).ResultsThe multivariable analysis in the elderly group revealed that when compared with patients receiving gross total resection (GTR), patients receiving biopsy had significantly worse CSS (HR = 3.72; 95% CI: 1.35–10.21; P = 0.011), whereas patients receiving subtotal resection (STR) had nearly the same CSS (HR = 0.83; 95% CI: 0.37–1.86; P = 0.653). Meanwhile, postoperative radiotherapy (PORT) showed no significant association with CSS in the elderly patient group (HR = 0.94; 95% CI: 0.42–2.12; P = 0.888).ConclusionSurgical resection is recommended for elderly patients with MM in the absence of surgical contraindications, but GTR does not present survival benefit in the elderly patients compared with STR. Additional large-scale clinical studies are needed to explore the survival benefit of PORT applied in patients with MM.
Measuring the Reliability of Postural Sway Measurements for a Static Standing Task: The Effect of Age
Authors: Lo Pei-Yi , Su Bo-Lin , You Yu-Lin , Yen Chen-Wen , Wang Shih-Ting , Guo Lan-Yuen 
Published: May 2022

Background: A force plate is used to determine the ability to balance ability. However, only some medical centers or laboratories are equipped with force plates because they are costly so a low-cost force plate is required for home care or health care institutes. Few studies compare the reliability of postural sway measurements in terms of age. This study proposes a low-cost force plate to select reliable parameters to evaluate postural sway.Objectives: To determine the intra-rater reliability of a novel force plate and the effect of age difference on the intra-rater test-retest reliability for the center of pressure (COP).Methods: Forty participants were enrolled for this study: 20 youths and 20 older adults. Participants stood on a custom-made and low-cost force plate with eyes opened and eyes closed to measure COP-related parameters. The within-day test-retest reliability was measured at two sessions on the same day and the between-days reliability was measured on two different days. The COP-related parameters include the average velocity of COP, the average velocity in the antero-posterior and medio-lateral directions, the mean distance of COP and the mean distance in the antero-posterior and medio-lateral directions. An intra-class correlation coefficient test with one-way random model was performed to determine the reliability of different variables within-days and between-days. The results were presented in single measurement of intraclass correlation coefficient (ICC), the standard error of measurements, and the minimal detectable changes of each COP-related parameters.Results: The novel low-cost force plate demonstrates excellent reliability in terms of the COP velocity related parameters for within- and between-day measurements. The ICC of COP distance related parameters were good to excellent reliability for between-day measurements (range: 0.43–0.84). Older adults demonstrated excellent reliability in terms of the mean distance for antero-posterior and the results were better than those for younger participants for the eyes-opened and eyes-closed conditions. The reliability in terms of the mean distance for medio-lateral was poor to good for older adults (range: 0.38–0.55), and excellent for younger participants.Conclusion: The novel and low-cost force plate reliably measured balance and age affects the reliability of different COP variables, so the results of this study were pertinent to the selection of COP measures.
Reading Ability in Patients With Tuberous Sclerosis Complex: Results of Chinese Character Reading and Reading Comprehension Tests
Authors: Lee Hom-Yi , Yang Sheng-Hui , Sheu Ji-Nan , Tsai Jeng-Dau 
Published: May 2022

BackgroundMost tuberous sclerosis complex (TSC) patients have neurological disorders and are at high risk of academic difficulties. Among academic skills, reading ability is the most important academic skill. The study applied the Chinese character fluency test to measure the word recognition and reading comprehension of TSC children to observe whether they have the characteristics of reading disability, as an indicator of the spectrum of reading ability in TSC patients.MethodsThe patients were assessed using the Chinese character fluency test and reading comprehension test to explore the differences in reading ability in terms of gender, age, epilepsy history, genotype, and intelligence level.ResultsOf the 27 patients, the assessment of reading accuracy showed statistical differences between intellectual level &gt; 80, PR (p = 0.024), and pass numbers (p = 0.018). For the fluency assessment, there was a difference between different intellectual level (p = 0.050). In the reading comprehension test, there was differences for intellectual level in positivity (p = 0.07) and pass numbers (p = 0.06).ConclusionThe Chinese character fluency and reading comprehension test measure the word recognition and reading comprehension and the spectrum of reading ability in TSC patients. All individuals with TSC, especially those with below average of intellectual ability, should be considered for potential academic difficulties.
Hydrochemical Assessment of Water Used for Agricultural Soil Irrigation in the Water Area of the Three Morava Rivers in the Republic of Serbia
Authors: Pivić Radmila , Maksimović Jelena , Dinić Zoran , Jaramaz Darko , Majstorović Helena , Vidojević Dragana , Stanojković-Sebić Aleksandra 
Published: May 2022

The assessment of the suitability and status of irrigation water quality from the aspect of its potential negative impact on soil salinization and mapping of spatial distribution within the area of the three Morava rivers, which includes the South, West, and Great Morava basins, was the purpose of this research. A total of 215 samples of irrigation water were tested, and their quality was evaluated based on the analysis of the following parameters: pH, electrical conductivity (EC), total dissolved salt (TDS), sodium adsorption ratio (SAR), and content of SO42−, Cl−, HCO3−, CO3 2−, Mg2+, Ca2+, Na+, and K+. The results showed that the average content of ions was as follows: Ca2+ > Mg2+ > Na+ > K+ and HCO3− > SO42− > Cl− > CO32−. The assessment of irrigation water suitability was determined by calculating the following indices: percentage sodium (Na %), residual sodium carbonate (RSC), permeability index (PI), magnesium hazard (MH), potential salinity (PS), Kelley’s index (KI), total hardness (TH), irrigation water quality index (IWQI). Based on Wilcox’s diagram, the USSL diagram, and the Doneen chart, it was concluded that most of the samples were suitable for irrigation. Using multivariate statistical techniques and correlation matrices in combination with other hydrogeochemical tools such as Piper’s, Chadha’s, and Gibbs diagrams, the main factors associated with hydrogeochemical variability were identified.
The Relationship between Stress Levels and the Performance of Nurses Caring for Covid-19 Patients at Private Hospital, Central Jakarta
Authors: Songka Karina , Ides Stefanus 
Published: May 2022

Covid-19 is a type of disease that is transmitted from one person to another through (droplets) when coughing or sneezing and the incubation period for COVID-19 is estimated to be between 1-14 days. The purpose of research are known the relationship between stress levels and the performance of nurses caring for Covid-19 patients at St Carolus Hospital, Central Jakarta. Descriptive correlation research with cross-sectional design was used. The sampling technique used purposive sampling and totaled 103 respondents. Data collected with questionnares using Google Forms. The results showed that the majority of respondents had severe stress levels (81.6%) and good performance (88.3%). The results of statistical analysis using Kendal Tau C showed there was no significant relationship between stress levels and nurse performance with p value (p = 0.597). Severe stress levels will affect the health of individuals physically, psychologically, socially and spiritually and have an impact on their performance. The suggestion for hospital can handle stress problems for nurses and maintain good nurse performance.
The Effect of Drill Method Through Handover In Improving Nurses' Ability To Use Personal Protective Equipment (PPE)
Authors: Arantha E. A Fransisca Renata , Wati Ni Made Nopita , Jayanti Desak Made Ari Dwi 
Published: May 2022

The provision of effective and efficient personal protective equipment (PPE) is very important for health workers who are vulnerable to contracting in treating COVID-19 patients. Drill method is a method of learning by providing repeated skill training. The purpose of this study was to find out the influence of drill method through handover in improving the ability of nurses to use PPE. Types of Pre-Experimental Research with a pre-post test design approach of one group. The number of sample was 13 respondents, the sampling technique used was purposive sampling. Data collection instrument used observation sheet. Data was analysed using the Wilcoxon Signed Ranks Test. The results showed that the average pre-test ability of nurses was mostly 75.95, namely 6 people (45.2%) fall into the category of sufficient, while the average ability of post test was mostly 93.62 which is as many as 13 people (100%) fall into the good category. Wilcoxon Signed Ranks Test analysis results obtained asymp. 0.001, meaning there is an influence of drill method through handover in improving the ability of nurses to use PPE. Drill methods can improve the ability of nurses, especially in using PPE through continuous training in accordance with the stages in the SPO.
Use of AI Techniques on Photonic Crystal Sensing for the Detection of Tumor
Authors: Sharma Sunil , Tharani Lokesh 
Published: May 2022

Tumors can cause severe problem to human beings. Sometime it can be a cause of death. Earlier there were lack of treatment and technological deficiency, due to which it was unable to detect tumor cells and even unable to offer proper treatment for these diseases. This study aims to use Photonic crystal (PhC) due to their ample choice of structures and litheness to endure with every sphere of influence has been utilized them twenty decade back to now a day and have extremely huge prospects in imminent future also. They have revealed their incidence in the field of imaging, sensing, fabricating industries, automation, medical, mechatronics, computronics, mechanochromic, underwater acoustic detection, pharma industries and nanoimprinting etc. If we are discussing about current and impending applications of PhC then it comprises smart sensing and detection of disunite diseases, anonymous viruses and a range of tumors. Artificial intelligence (AI) is also playing incredibly essential role in analyzing and creating entities equivalent to the change in human behavior. AI tools and techniques are utilizing to create intelligent entities through which it is accomplishing countless feats. The PhC along with the artificial intelligence are utilizing as Optical Neural Network (ONN), Artificial Neural Network (ANN), Cellular Computing, Plasma Technology, Parallel Processing, Image Processing etc. Here in this study designated photonic crystal has been used for the detection of infected cell in human body. Sometimes these infected cells are unable to trace by normal pathological investigations and slowly they take a shape of Tumors. But thanks to Photonics crystal sensors that they have made it true not only for detection but we can say for early detection of such tumors in human body. These early detection and proper investigation is possible only because of AI impacts on photonics crystal. This study focuses on detection and observation of bio molecules for selectivity, sensitivity, reflectivity and concentration. By change in wavelength i.e. from 1.5 μm to 4 μm the refractive index (RI) of tumor cell can be measured which is observed by measuring sensitivity between 11258 nm/RIU to 32358 nm/RIU. Tumors have refractive indices varies between 1.3342 to 1.4251. It is observed that sarcoma level is directly proportional to the RI of tumor. Various AI algorithms like support vector machine (SVM) obtained accuracy as 96%, K- nearest neighbor (KNN) shows as 70%, logistic regression (LR) shows as 88%, random forest (RF) show it as 90%, fuzzy logic (FL) and artificial neural network (ANN) observed accuracy as 93% and 95% respectively.
ANALISA WEBSITE MOODLE PT XYZ DENGAN MENGGUNAKAN METODE WEBQUAL 4.0
Authors: Rasman Emeraldi Destian 
Published: May 2022

Kualitas adalah fitur-fitur atau produk yang memenuhi kebutuhan pelanggan dan dapat memenuhi kepuasan pelanggan. Website merupakan hal yang harus diperhatikan oleh institusi dalam hal ini institusi pendidikan, karena digunakan oleh pengguna yang ada didalam institusi tersebut. Untuk mengetahui kualitas website maka perlu dilakukan pengukuran kualitas website akademik yang dimiliki oleh PT XYZ. Instrumen yang digunakan pada penelitian ini adalah Webqual 4.0 (Barnes & Vidgen, 2001) yang terdiri dari 4 variabel yaitu Usability, Information Quality, Service Interaction, User Satisfaction, dan memiliki 14 indikator. Teknik analisis yang digunakan adalah Regresi Linear Berganda yang akan memberikan gambaran mengenai hubungan antara kualitas website dengan kepuasan pengguna. Penelitian ini dilakukan dengan menyebarkan kuesioner kepada 68 mahasiswa PT XYZ. Uji validitas, reliabilitas, dan analisa data dilakukan dengan menggunakan aplikasi SPSS 16. Hasil analisa dalam uji parsial menunjukkan bahwa kualitas kegunaan (Usability) dan layanan interaksi (Service Interaction) memiliki pengaruh terhadap kepuasan pengguna (User Satisfaction). Sedangkan kualitas informasi (Information Quality) tidak memiliki pengaruh terhadap kepuasan pengguna (User Satisfaction) karena dari hasil uji menunjukkan pengaruh negatif dan tidak memenuhi syarat uji signifikansi dan uji t . Pada hasil uji F, menunjukkan bahwa Kualitas kegunaan (Usability), Kualitas Informasi (Information Quality), dan (Service Interaction) secara bersama-sama berpengaruh signifikan terhadap kepuasan pengguna (User Satisfaction). Dan hasil pengujian seluruh variabel bebas Usability, Information Quality, dan Service Interaction menunjukkan tingkat kepuasan pengguna atau User Satisfaction sebesar 41,9%. Dimana semua variabel bebas mempengaruhi kepuasan pengguna sebesar 41,9%.
ELT During The Covid-19 Pandemic; Practices and Challenges
Authors: Syafi'i Ahmad 
Published: May 2022

The purpose of this study is to evaluate the practices and challenges of online learning or so called Learning From Home (LFH) in English Department during the even semester 2019/2020 academic year. The subject of this study are 8 lecturers of English Department at STKIP Al Hikmah. This study employed descriptive qualitative research design. The instrument used is daily online teaching monitoring and evaluation questionnaire. The result of this study is categorized into five aspects namely 1) online learning applications frequently used by the lecturers are WhatsApp, Google Classroom, Schoology, Quizizz, E-mail, Zoom Cloud Meeting, Email, and Youtube 2) online learning activities frequently conducted by the lecturers are uploading materials, discussion forum, conducting quizzes, uploading assigment,, and video conferences, 3) scheduled assignment submission rate, 4) students’ participation rate and 5) challenges and alternative solution proposed by the lecturers during the online learning.
An Analysis of The Politeness Strategy used in Mata Najwa Talk Show on Trans7
Authors: Silitonga Dwi Handayani 
Published: May 2022

This study aimed to describe the Politeness Strategies used in Mata Najwa Talk Show. This study applied a qualitative research design to explore the politeness strategies used by the participants in Mata Najwa Talk Show in their interactions. The participants in this study were Najwa Shihab as a host, Erick Thohir and Nadiem Makarim as guests. The data in this study were in the form of utterances that contain politeness strategies.
The result showed that the host not only use Positive Strategy to reveal the guests’ issue but also use a Negative strategy to reduce the interference with the guests’ freedom of action. The guests tend to use Positive Politeness because they tried to convince society about their new policies and state that they share the same specific wants, goals, or values, namely a better condition for this country. From the analysis, the researcher found out the result that Positive politeness (76,32%), Negative Politeness (18,42%) and off Record Strategy (5,27%) and there is no Bald Record Strategy used in this analysis.
The Correlation Between English Language Learning Strategies And Students Thinking Style At The Second Grade Of Man 1 Kolaka
Authors: Suryadi Ray , Kamaruddin Firdayana 
Published: May 2022

This research was conducted at MAN 1 Kolaka. The objective of this reaseach is to find out information and data weather there is any correlation between English language learning strategy and students’ thinking style at the second grade AGAMA I of MAN 1 Kolaka. The research design is descriptive quantitative. The data were collected through questionnaires. English Language Learning Strategy at the second grade AGAMA I of MAN 1 Kolaka are Metacognitive with the total frequency is 47% percent and Studets’ Thinking Style are Extrovert with the total persentage is 53%. The Population of the research was the second grade students of MAN 1 Kolaka and the sample of the research was class AGAMA I which consisted of 15 students. The data analysis used in this research was product moment formula which showed that there was no any correlation between English Language Learning Strategy and Students’ Thinking Style. It could be synthesized that hypothesis were r-count was lower than r-table. So H1 was rejected and H2 was accepted. The coefficient Correlation between English Language Learning Strategies and Students’ Thinking Style did not have any significant correlation with the r-count = -0,218 was lower than r-table 0,514 at the significance level 5% and degree of freedom (df) was 15 (-0,218>0,514). Therefore, it was categorized as low correlation. H0 and H1 was rejected and H2 was accepted.