bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation and Correlation of Preoperative Serum C- Reactive Protein, Neutrophil-lymphocyte Ratio and Platelet-lymphocyte Ratio for Cervical Metastasis in Patients of Primary Oral Squamous Cell Carcinoma
Authors: Wadewale Sanjana , Bhola Nitin 
Published: February 2022

Background: The influence of cervical metastasis on prognosis in a person who is suffering from oral squamous cell carcinoma (OSCC) has been notorious. C- reactive protein (CRP) is a prior biomarker for inflammation. Recent literature provide evidence of systemic inflammatory markers playing important role in determining survival rate on patient with OSCC. Hence, in current study the “utility of Neutrophil-lymphocyte ratio (NLR) ,Platelet-lymphocyte ratio (PLR), and serum CRP are evaluated and correlated for cervical metastasis”.
Objectives: This study intends to evaluate and correlate preoperative serum CRP, NLR, and PLR for cervical metastasis in patients of primary oral squamous cell carcinoma.
Methodology: The clinicopathological data, CRP and the preoperative complete blood investigation details were obtained from 40 primary OSCC patients who will undergo surgery. The optimal cut-off value of CRP, PLR and NLR was determined. The prognostic significance of markers will be determined by Univariate and multivariate analysis.
Expected Results: The elevation of CRP, NLR, and PLR levels will significantly evaluate and correlate with cervical metastasis.
Conclusion: Preoperative serum CRP, NLR, and PLR level will be a prognosticator in OSCC.
Prevalence of Anaemia in Females of Reproductive Age Group
Authors: Purwar Ananya , Anjankar Vaibhav 
Published: February 2022

Background: Anemia is a significant public health indicator linked to poor health outcomes. The restricted nature of available data makes it difficult to relate the iron status of pregnant women. It is yet unclear whether the therapy option is most successful in reducing postpartum anemia symptoms.
Aim and Objective: To discuss the existence of anemia in females of conceivable age and during pregnancy and the causes and treatments for the condition.
Description: The woman ought to contain bodily stores of irons 500 mg, which corresponds to serum ferritin levels of 60-70 g/L, for completing a normal pregnancy along with no intake of iron supplements even without developing an iron deficiency or iron-deficiency anemia. Iron deficient anemia caused by a lower percentage of iron is the most common anemia worldwide. Anemia is a prevalent problem among HIV-positive persons, especially women. It can make you feel restless, reduce your quality of life, and make it more likely that your HIV infection will worsen.
Conclusion: The experimental relevance of a few good temporary fatigues counting female patients alongside blood transfusion remains unknown. Also, such small benefits must get weighed against understood risks, such as maternal mortality (not stated) as well as maternal immunological sensitization, all of that might disrupt subsequent pregnancies. When comparing oral iron to a placebo, it's unclear if effectiveness (symptom alleviation) overcomes the documented gastrointestinal side effects.
Succinct Review Article on Male Sterility Diagnosis, Symptoms, and Treatment
Authors: Joshi Amey , Sawal Anupama 
Published: February 2022

Background: Interspecific hybrid male sterility is a common occurrence in nature and plays a vital role in species reproductive isolation. Recently several studies have suggested a decline in the quality of semen. About half of the infertile causes are in men; the rate increases in the infertile couples. Some therapy for male sterility; medication, surgery, or assisted reproductive technology (ART). Medicinal effects are not expected, and surgical cases are localized for indication. Moreover, since most male sterility is idiopathic insufficiency of spermatogenesis, a recent tendency in the male-sterile therapy is ART such as IVF-ET, ICSI, TESE, etc.
In oncology and Graves' disease, retraction of the thyroid gland is implicated in the pathogenesis of destruction of the endocrine glands, extraneous division of the superior and inferior laryngeal nerves, collapsed lung associated with cardiovascular destruction, or the possibility of remnant glandular tissue is remaining. This research aimed to identify how common thyroid gland anomalies in anatomy and development are to reduce the risks of thyroid surgical problems. There were a total of 20 corpses dissected. The pyramidal lobe of the thyroid gland, the levator glandule thyroideae, or the half or total disappearance of the isthmus has all been investigated. The gland's right and left lobes were measured length, maximal transverse, and anteroposterior extent. The bulk of these anatomical discrepancies can be attributed to an organogenesis mistake. Thyroid dysgenesis comprises ectopic thyroid, hemiparesis, hemiagensis, hypoplasia, and anatomical abnormalities in the thyroid gland produced by improper organogenesis.
A Retrospective Study on Identification of Anterior Loop Pattern of Mental Nerve Entry into Mental Foramen in Digital Orthopantomography among South Indian Population
Authors: Srithika M. , Prathap Lavanya 
Published: February 2022

Background: In the premolar location of mandible, the mental nerve's entry into the mental foramen pattern is a significant landmark. Different patterns of mental nerve entrance have been discovered. The current experiment was attempted to detect the different entry routes of the mental nerve into the mandible using panoramic radiographs, which are employed in pre-surgical evaluation.
Materials and Methods: The current study used a total of 200 panoramic radiographs collected for diagnostic purposes. The location and entrance pattern of the mental nerve on the both sides were noted on the radiographs. Straight, looping, and perpendicular entry patterns were identified in the data. The data is tabulated and statistically analysed in SPSS software using Chi-square.
Results: The existence of an anterior loop was determined to be the most usual pattern of entry of the mental nerve, accounting for 79 percent of the total radiographs examined 21 percent , and a perpendicular pattern 6 percent. The p value is 0.432 and p value 0.309, with respect to age and gender respectively which is statistically not significant.
Conclusion: The findings obtained from the study within the limits, it can be stated that the straight pattern of anterior loop of mental nerve was the most common. A panoramic radiograph may be a viable radiological tool for detecting the existence of an anterior loop that should be confirmed in order to plan surgical treatments in the mandibular premolar region prior to surgery.
Assessment of Patient Satisfaction in IPD Settings of AVBRH and Designing Strategies for Providing Patient-centric Care
Authors: Seth Pushpanjali , Shinde Vitthal , Gudhe Vandana 
Published: February 2022

Background: Health industry is changing and growing at a very rapid phase. The patient is the most essential stakeholder in healthcare now. The Healthcare industry is a service industry where patient satisfaction are of paramount importance for the success of any organization. Healthcare is becoming more and more customer-centric. Patient satisfaction encompasses patients’ expectations, perception, and overall experience of healthcare services. Patient feedback helps a lot in improving services to patient satisfaction. This study aims to assess the satisfaction level and causes of dissatisfaction in ABVR Hospital and provide patient-centric healthcare.
Methodology: This will be a descriptive cross-sectional study. Patient satisfaction survey questionnaires will be administered, and personal interviews will be conducted with 50 randomly selected patients admitted to AVBRH. The qualitative and quantitative data will be analysed using appropriate statistical tools.
Results: Key reflections are expected about patient satisfaction level regarding healthcare services at AVBRH which can guide to frame patient-centric care policies.
Conclusion: Patient perception and feedback should be considered for formulating quality improvement strategic decisions. Pas the end-user of service, patients can judge the organizational and environmental dimension, empathetic work culture, and clinical aspect.
Seizures Presenting as ADHD: A Case Report
Authors: K. S. Anies Siya , Kallan Fadi Mohamed , Kolenchery Julianna Jinson , D'silva Vismaya Rachel , Nagdive Amit B. , Sethi Siddharth 
Published: February 2022

ADHD (Attention Deficit Hyperactivity Disorder) is a neurodevelopmental disorder that affects a large proportion of children. ADHD is associated with an increased risk of seizures and is characterised by inattention, restlessness, and impatience.
A 6-year-old boy with ADHD presented to the Psychiatry Out-Patient Department with complaints of aggressive behaviour and restlessness. Trademark symptoms such as difficulty in sustaining concentration, not following instructions, running about, not being able to sit in one place, and verbally and physically abusive behaviour were noted in the patient.
Atomoxetine and Risperidone were prescribed for inattention and behavioural misconduct, respectively. Due to lack of improvement and a seizure suggestive incident an EEG investigation was instigated; it showed seizure activity for which Sodium Valproate was initiated for the same. Due to adverse effects, Oxcarbazepine was additionally included. Oxcarbazepine showed the most effective in treatment and progress continued with the intake of the drug. Currently, the boy is showing near total improvement and is on Atomoxetine 20 mg, Oxcarbazepine 600 mg and Sodium Valproate 400 mg, all of the above in divided doses.
This case report aims at highlighting the manifestation of unprovoked seizure activity in a patient previously diagnosed with ADHD with conduct disorder.
Several medical conditions in children mirror ADHD symptoms, making diagnosis difficult. For accurate treatment, it's crucial to rule out a differential diagnosis. With the help of this case, we can shed some light on the lack of knowledge and protocols in the management of hyperkinetic disorders, which has resulted in the spike of misdiagnosed cases across the country.
Carcinoma of Breast: A Case Report
Authors: Thakare Pratiksha , Ankar Ruchira , Sharma Ranjana , Gujar Samruddhi , Sheikh Shakib 
Published: February 2022

Background: In Indian women, breast cancer is the most frequent type of cancer. Breast cancer affects 30 out of every 100,000 women in India.
Case Report: A female patient of 70 years old was admitted to Female surgery Ward-33, Unit-3, AVBRH on 19th January with a chief complaint of lump in upper outer quadrant of the right breast, hardness and non-tenderness of right breast since 2 months. The patient was ok. She had complained of a lump in the upper outer quadrant of her breast for 2 months, and it had appeared gradually. During a physical examination, some clinical findings were obtained i.e., lump in a breast was gradually progressive, and non-tenderness and a nonmobile lump in upper outer quadrant of right breast, no history of fever, nausea vomiting, bloody discharge from a nipple. After that patient was undergone on the routine investigation in that Haemoglobin- 8.4gm% was decreased, Total Red Blood Cell count 2.88 cumm decreased, Total Leucocyte Count -17800 cumm increased. Fine needle aspiration cytology show metastasis of breast and ultrasonography shows an irregular strangulated hypoechoic mass of approximately 3.5*1.9 cm at the outer upper quadrant of the right breast. After histopathology report revealed that patient having metastasis of right breast and she was undergone on treatment of chemotherapy.
Conclusion: This case report was of great relevance for academics, its provided to improve knowledge about breast cancer, to encourage the practice of BSE making women aware of the importance of this exam.
Assessment of Compliance Level of Healthcare Personnel at AVBRH to Appropriate Hand Hygiene Practices: A Study Protocol
Authors: Ramteke Prachi , Naik Rupali , Gudhe Vandana 
Published: February 2022

Background: In COVID scenario World Health Organization (WHO) recommends washing hands with water and soap or alcohol-based hand rubs for cleaning hands. Hand hygiene has been considered a central component in every program related to infection control. It is applicable to healthcare personnel handling critical patients as well. Poor hand hygiene during intrapartum and newborn care is associated with increased death rates among newborns due to sepsis. This study aims to assess the knowledge, attitude, and practices of handwashing by healthcare staff in the hospital.
Methodology: This is an observational study which is conducted among the healthcare personnel at AVBRH hospital, Wardha. A tool consisting of a self-administered observation record form on knowledge and practices of handwashing will be used for data collection from 60 healthcare workers. Data will be analyzed using appropriate statistical tests.
Expected Results: Appropriate levels of knowledge and practices about proper hand hygiene are expected within healthcare workers of AVBRH. Availability of alcohol-based hand rubs, sanitizers, soap and water is expected at all times.
Conclusion: Considering the pandemic situation, the availability and use of hand sanitizers can be effective to limit the spread of infections COVID -19.
Case Report on Acute Pancreatitis
Authors: Hadke Sonal , Sakharkar Sheetal , Raut Arati , Dhengare Archna , Gujar Samrudhi , Morey Swapna , Taksande Archana , Kumari Darshna , Pande Khushbu 
Published: February 2022

Introduction: Upper-abdominal pain is frequently caused by acute pancreatitis. A diagnosis based purely on symptoms and signs is difficult because its clinical features are similar to those of a range of other acute diseases. Acute pancreatitis is diagnosed using two of the 3 criteria given below: Stomach pain, increased serum lipase and/or amylase levels, and abnormal abdominal image processing are all signs of pancreatitis. When it comes to diagnosing acute pancreatitis, lipase has been demonstrated to have good specificity and sensitivity. Pain in the stomach that appears to originate from the pancreas When it comes to diagnosing acute pancreatitis, abnormal abdominal imaging and/or serum lipase and/or amylase values larger than three times the upper period of normal Lipase have been proven to have good sensitivity and accuracy.
MAIN Symptoms And / OR Important Clinical Findings: For 5 days, I had abdominal pain, difficulty swallowing, decreased appetite, generalized weakness, fever, and loose movements.
Diagnostic Evaluation: He is a male patient who is 22 years old. And all diagnostic testing has been completed. Contrast-enhanced computed tomography of the abdomen, ultrasonography, complete blood count: 12.8 gm/dl.
Therapeutic Intervention: Patient was treated injection meropenem 500 milligram thrice a day, injection Levoflox 500 milligram one time a day, injection pan 40 milligram one time a day, injection Emeset 4 milligram thrice a day, injection Tramadol 100 milligram thrice a day, injection Thiamine 100 milligram thrice a day, injection mucomix 600 milligram twice a day, injection Doxy 100 milligram twice a day, Injection Hydrocort 100 milligram thrice a day, Syrup, Kesol 2TSP thrice a day.
Outcome: The patient’s overall condition gotten better.
Nursing Perspectives: Changing the fluid dextrose normal saline and ringer lactate were set up in the first place. On an hourly basis, keep track of your vital signs and blood pressure. Maintaining the patient’s intake and output chart, as well as providing adequate rest and sleep. Administered drugs as directed by the doctor.
Conclusion: During the past five days, patients complained of abdominal pain, nausea and vomiting after each meal, difficulty swallowing, decreased appetite, generalised weakness, fever, and loose movements at Acharya Vinoba Bhave Rural Hospital. These symptoms were eased with proper treatment, and the patient is currently in good health.
A Study Protocol for Evaluation of Microcytic Hypochromic Anemia by High-Performance Liquid Chromatography (HPLC)
Authors: Kharche Kaustubh Vilasrao , Bhake Arvind , Vagha Sunita 
Published: February 2022

Background: One of the most regularassessments done in clinical practice is anemia. Different levels classify the anemiasbased onthe numerical value of hemoglobin, alteration in the morphology and chromium, underlying etiologies, red cell volumetric parameters and functionally depending on pathophysiologic processes of anemia. Microcytic hypochromic anemia (MCHC) has different underlying causes, including iron deficiency anemia, beta-thalassemia trait, and hemoglobinopathies. Before planning the treatment, assessing the hemoglobin for its variants and the detection of abnormal hemoglobinis mandatory. High-performance liquid chromatography (HPLC) has proved to be significant for the evaluation of MCHC because of its superior separation and quantification analytical powers.The present study has been undertakingthat anemia is the most prevailing and commonly treated clinical state managed by numerous nutritional supplements without much being done to know the underlying etiology or without evaluation of hemoglobin for its abnormalities.
Methods: This will bean observational (Prospective and Retrospective) study. Blood samples of 100 patients will be evaluated by HPLCBio-Rad variant,and various hemoglobin patterns; associate dhemoglobinopathies will be evaluated.
Results: The observations will be made according to the objectives and tabulated, which will be subjected to statistical tests for their significance and conclusions.
Conclusion: This study would contribute to understanding and knowing the etiology of MCHC in the population that our tertiary care hospitals serve.
The Effects of Plasma Exchange on Diffuse Alveolar Hemorrhage in Severe Vasculitis – A Case Study
Authors: Sahu Monali Rajendrakumar , Wairagade Tanvi Dilip , Wairagade Sonali Dilip , Ambad Ranjit S. , Muley Parikshit 
Published: February 2022

Introduction: Rapidly progressive glomerulonephritis (RPGN) and widespread alveolar hemorrhage define ANCA-associated vasculitis (AAV), a rare, life-threatening illness (DAH).
Case Presentation: An elderly female came with lower limb weakness and oliguria had features suggestive of RPRF and fluid overload. She developed hemoptysis with respiratory failure despite hemodialysis and intravenous steroids. The diagnosis of patients was pulmonary-renal syndrome– DAH in the setting of ANCA and based on the HRCT chest and positive p-ANCA report. She had excellent responses to intravenous pulse steroids, cyclophosphamide, and plasma exchange.
Conclusion: Based on observation showed the importance of immediate intervention in potentially fatal disease DAH in AAV.
Nutrient fertilization by dogs in peri‐urban ecosystems
Authors: De Frenne Pieter , Cougnon Mathias , Janssens Geert P. J. , Vangansbeke Pieter 
Published: February 2022

Abstract

(Semi‐)natural ecosystems provide many important benefits to nature and people, but are often located near populated and urbanized areas across the globe. During recreational activities, many people bring dogs into peri‐urban forests and nature, but their nutrient inputs per unit space and time via dog faeces and urine into ecosystems remain scarcely quantified.

Here, we estimate net fertilization rates of dogs in peri‐urban ecosystems, with a focus on nitrogen (N) and phosphorus (P) because of their evident effects on plant biodiversity. We used 487 direct‐count censuses over 1.5 years to collect accurate dog abundance data per hectare per year in four sites in peri‐urban forests and nature reserves in Belgium. Based on estimated dog densities and a systematic literature search of nutrient concentrations in urine and faeces, we calculate N and P fertilization rates from urine and faeces deposits, also propagating uncertainty and variability in these estimates.

We find that canine N and P fertilization rates on average amount to 11 kg N (more or less equally from urine and faeces) and 5 kg P (predominantly from faeces) per hectare per year, respectively. These estimated amounts are substantial when compared to atmospheric inputs of N and extractable amounts via traditional nature management (e.g. mowing and hay removal).

Our estimated dog N and P fertilization rates in peri‐urban forests and nature are substantial. Such levels of nutrient inputs may considerably influence biodiversity and ecosystem functioning, and co‐determine restoration outcomes. Our results underpin the need for managers and policy makers to more often (i) consider currently neglected nutrient inputs by dogs in management plans and restoration goals, (ii) communicate to dog walkers the role of their dog as ‘fertilizer’ and highlight the necessity to remove at least canine solid faecal waste, (iii) in sensitive oligotrophic ecosystems with species adapted to nutrient‐poor soils, establish nearby off‐leash dog parks, enforce the use of short leashes and/or apply dog bans such that high dog abundances can be avoided.
Onboard cone‐beam CT‐based replan evaluation for head and neck proton therapy
Authors: Stanforth Alexander , Lin Liyong , Beitler Jonathan J. , Janopaul‐Naylor James R. , Chang Chih‐Wei , Press Robert H. , Patel Sagar A. , Zhao Jennifer , Eaton Bree , Schreibmann Eduard E. , Jung James , Bohannon Duncan , Liu Tian , Yang Xiaofeng , McDonald Mark W. , Zhou Jun 
Published: February 2022

AbstractPurposeQuality assurance computed tomography (QACT) is the current clinical practice in proton therapy to evaluate the needs for replan. QACT could falsely indicate replan because of setup issues that would be solved on the treatment machine. Deforming the treatment planning CT (TPCT) to the pretreatment CBCT may eliminate this issue. We investigated the performance of replan evaluation based on deformed TPCT (TPCTdir) for proton head and neck (H&N) therapy.Methods and materialsTwenty‐eight H&N datasets along with pretreatment CBCT and QACT were used to validate the method. The changes in body volume were analyzed between the no‐replan and replan groups. The dose on the TPCTdir, the deformed QACT (QACTdir), and the QACT were calculated by applying the clinical plans to these image sets. Dosimetric parameters’ changes, including ΔD95, ΔDmean, and ΔD1 for the clinical target volumes (CTVs) were calculated. Receiver operating characteristic curves for replan evaluation based on ΔD95 on QACT and TPCTdir were calculated, using ΔD95 on QACTdir as the reference. A threshold for replan based on ΔD95 on TPCTdir is proposed. The specificities for the proposed method were calculated.ResultsThe changes in the body contour were 95.8 ± 83.8 cc versus 305.0 ± 235.0 cc (p < 0.01) for the no‐replan and replan groups, respectively. The ΔD95, ΔDmean, and ΔD1 are all comparable for all the evaluations. The differences between TPCTdir and QACTdir evaluations were 0.30% ± 0.86%, 0.00 ± 0.22 Gy, and −0.17 ± 0.61 Gy for CTV ΔD95, ΔDmean, and ΔD1, respectively. The corresponding differences between the QACT and QACTdir were 0.12% ± 1.1%, 0.02 ± 0.32 Gy, and −0.01 ± 0.71 Gy. CTV ΔD95 > 2.6% in TPCTdir was chosen as the threshold to trigger QACT/replan. The corresponding specificity was 94% and 98% for the clinical practice and the proposed method, respectively.ConclusionsThe replan evaluation based on TPCTdir provides better specificity than that based on the QACT.