bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilising gamification for online evaluation through Quizizz: Teachers’ perspectives and experiences
Authors: Arifin Zainal , Setiawan Budi 
Published: June 2022

During the pandemic, the 2019 novel coronavirus disease (COVID-19) has had a tremendous and massive impact on the entire cross-level education system in Indonesia and the global realm. This study aimed to look at the reflections of gamification activities that are used as a formative assessment tool in learning environments based on academic accomplishment and teachers’ engagement. The existing resource presented in this study in the form of ‘Quizizz’ can effectively transform formal education patterns into online education patterns assisted by virtual classrooms and other online learning media for the evaluation process. The method used in this research is phenomenology to investigate the perspectives and experiences of Indonesian secondary school teachers about remote Quizizz evaluation during the COVID19 pandemic to determine the teacher’s perspectives and experiences for media utilisation strategies in the online evaluation. The results of this study indicate that in learning activities during the COVID-19 pandemic, training is needed for teachers to respond to and overcome problems related to changes in the online evaluation process in the education system. Identifying teachers’ perspectives and experiences for an online-based evaluation process during the pandemic will contribute positively to achieving maximum student-learning goals and outcomes.

Keywords: Perspectives; experiences; evaluation; online learning; covid-19;
The development of research activity with schoolchildren
Authors: Kayumova Maiya , Xembayeva Saule , Fominykh Nataliia , Pfeifer Nelli , Zumadirova Kainysh 
Published: June 2022

The primary goal of this study was to unveil the key features of research activity in the context of school education and identify the most significant barriers to it. This was to be achieved by conducting a structured survey of 174 teachers. Further interviewing of 10 teachers of the most successful schools in these terms intended to detail the characteristics of research activities in the considered educational institutions. The systematization and generalization of the collected results was the final stage of this analysis. The data obtained in the course of the investigation confirmed the idea that most students should take a special course on introduction to research from their first days at a university. In practice, the research results can be used in the implementation of STEM methods, scientific education, and the involvement of schoolchildren in research activities in the educational programs of most developing countries that have similar problems.

Keywords: entrepreneurial education; research activity; science education; soft skills; STEM; university preparation programs.
Pedagogical technologies for the emotional intelligence of a music teacher
Authors: Kakimova Laura Sh. , Balagazova Svetlana T. , Mukeyeva Nurzhamal E. , Berdenova Assel Zh. , Azhgereyeva Kalamkas B. 
Published: June 2022

Today, in higher artistic and artistic-pedagogical educational institutions, emphasis is placed on the formation of the technological culture of future music teachers through the application of innovative technologies in vocal education. In higher artistic and artistic-pedagogical educational institutions, special attention is paid to the formation of the technological culture of future music teachers through the application of innovative technologies in vocal education. The teacher is considered to be a professional with personal phenomenon thinking, technical knowledge, practical skills, and the ability to use creative pedagogical tools, based on the value of technological culture, the ability and the way of technology worldview, and this is formed and applied to creative artistic and pedagogical activities. In this study, it was requested to determine the opinions of the music teachers who teach in modern education conditions on the pedagogical approaches to the concept of emotion. Within the scope of this research, interviews were conducted with 25 music teachers. The study group was selected on the basis of volunteerism for the research. Three unstructured interview questions prepared by the researcher were asked. As a result of the research, it was explained by using the content analysis method. It has been concluded that emotional intelligence gains positive attitudes in the music education process.

Key words: Music teacher, emotional, technology, pedagogy, education, teaching;
Roteiros de difusão das geociências sob a nova visão da sociedade pós-pandemia
Authors: Carneiro Celso Dal Ré , Pereira Sueli Yoshinaga , Ricardi-Branco Fresia Soledad Torres , Gonçalves Pedro Wagner 
Published: June 2022

Percorremos 2021 concentrados na seleção e editoração dos 56 trabalhos que integram o volume 17 de Terræ Didatica, com a esperança de que um dia haverá maior controle sobre a pandemia de Covid-19 e seus terríveis efeitos, mas o desafio do combate ao vírus ainda demandará esforços dos pesquisadores, das autoridades e da população. As páginas da revista foram permeadas por resultados de pesquisas sobre os efeitos da pandemia na educação geocientífica, com destaque para propostas inovadoras, que revelam o potencial de contribuição das Ciências da Terra ao esforço coletivo de enfrentamento da catástrofe. Reunimos exemplos, ao longo do ano, bem como resultados experimentais e evidências notáveis, de que “as sociedades humanas precisam reaprender a se relacionar com a natureza” (Apresentação de Terræ Didatica, 2021). Plantam-se sementes de inovação quando o pesquisador-educador contextualiza aspectos da realidade local para trabalhar com seus alunos questões polêmicas sobre a relação entre as sociedades humanas e a natureza. Antes de iniciar o trabalho em sala-de-aula, porém, é necessário ampliar e reformular pontos-de-vista para problematizar temas sobre a complexa e intrincada teia da vida na Terra. Cada educador precisa se capacitar e aprofundar conhecimentos sobre a dinâmica ambiental. Os temas da Geoética e da Geoconservação inspiram pesquisas ininterruptas, ao mesmo tempo em que se acumulam estudos-de-caso sobre problemas significativos de degradação ambiental que podem ser mais bem compreendidos a partir das dificuldades elementares – e extremamente desiguais – vivenciadas pelas comunidades.
Não se trata de assuntos novos; são temas estudados e debatidos há um bom tempo. Contudo, após o evento crítico da pandemia, conceitos relacionados à dinâmica da Terra e aos impactos da interferência humana nos processos naturais virão à tona e poderão mostrar que o modelo de sociedade atual deixou de ser eficaz; ao contrário, revela-se frágil e agressivo aos ambientes terrestres e aos ecossistemas. Pequenas boas mudanças poderão advir, e a educação exercerá papel importante na mudança de paradigmas.
The Effect of Trehalose Sugar on Insulin Resistance in Old Rats by Assessing HOMA-IR (Homeostasis Model Assessment-Insulin Resistance)
Authors: Ismi Desya Faradila , Aminuddin Aminuddin , Santoso Arif , As'ad Suryani , Yustisia Ika , Idris Irfan 
Published: June 2022

Background: Insulin resistance is a condition in which insulin cannot take up glucose, increasing blood glucose. Elderly people are more exposed to insulin resistance, requiring dietary interventions that extend longevity. Trehalose, a naturally occurring sugar, showed potentially reduce insulin resistance which can be measured using the HOMA-IR index.
Objectives: This study aimed to assess HOMA-IR levels as a parameter of insulin resistance in old rats after giving trehalose sugar.
Methods: Experimental research with 28 male Wistar rats (Rattus novergicus) was separated into 4 groups, the control group of young rats (Group A), the control group of old rats (Group B), a group of old rats that were given 2% Trehalose solution (Group C), and a group of old rats that given 2% sucrose solution (Group D) that observed for 8 weeks.
Results: The results showed differences in HOMA-IR levels (p<0.001) between old and young subjects. The intervention in Group C was optimal in reducing levels of HOMA-IR (p<0.001) by 18.2% compared with the old control, while Group D increased levels of HOMA-IR by 14.3% (p<0.001) compared with the old control. The age of the subjects with HOMA-IR level is positively correlated (p<0.001; r=0.721) and the weight of subjects with the HOMA-IR level is also positively correlated (p<0.001; r=0.698), indicating that the older and the greater weight of subject resulting in the bigger of HOMA-IR value.
Conclusion: Trehalose is effective in reducing HOMA-IR levels as a parameter of insulin resistance in old rats.
Tumor-to-Tumor Metastasis: Renal Cell Carcinoma Metastasizing to a Lipoma of the Thigh
Authors: Martin Kelsey , Rivera-Pintado Christopher , Cerniglia Katherine , Usmani Kudret , Zhu Gord , Kim Tae Won B. 
Published: June 2022

Case:
A 73-year-old man with a medical history significant for renal cell carcinoma (RCC) presented with widespread osseous metastases and imaging suspicious for RCC metastasizing to a lipoma interdigitated within the right vastus lateralis. The patient's pathological fractures were surgically addressed, and the lipoma excised. Final histology revealed a thigh lipoma involved by metastatic RCC without direct extension.

Conclusion:
Tumor-to-tumor metastasis is a rare occurrence, with RCC typically being the most common “recipient” tumor. This is the first case to the best of our knowledge of RCC metastasizing to a lipoma, highlighting a rare phenomena in a patient with metastatic disease.
Fatal Fulminant Fat Embolism Syndrome in Adult Spine Deformity Surgery
Authors: Mohar Janez 
Published: June 2022

Case:
A 68-year-old woman was scheduled to undergo elective correction of coronal spinal malalignment after a previous lumbar instrumented fusion. In the final stages of the operation, the patient became hemodynamically unstable. Her systemic condition worsened subsequently, leading to cardiac arrest followed by unsuccessful resuscitation. An autopsy revealed a massive fat embolism in the lungs.

Conclusions:
The diagnosis of fat embolism syndrome (FES) is clinical, and treatment is supportive, with no clinical or investigative criteria that can facilitate diagnosis in a patient under general anesthesia. This is the first description of FES in adult spinal deformity surgery.
Bilateral Incomplete Atypical Femur Fractures with Severe Bowing Treated Using Elastic Intramedullary Nails
Authors: Okubo Naoki , Yoshida Takashi , Tanaka Kazuya , Asano Mizuki , Nakazawa Taku , Ohara Masato , Hosoi Kunihiko , Takahashi Kenji 
Published: June 2022

Case:
A 77-year-old woman with bilateral symptomatic atypical femoral fractures (AFFs) and severe anterolateral bowing due to long-term bisphosphonate administration was treated using stainless elastic intramedullary nails. Weight-bearing pain disappeared immediately after surgery. Radiographs obtained 1 year postoperatively showed fracture healing.

Conclusion:
Although intramedullary nail insertion has been recommended for symptomatic incomplete AFFs, in cases of severe bowing, rigid nail insertion was often challenging, and the complication rates were higher than those with mild bowing. The advantage of our method is easy insertion, suggesting effective treatment.
Identifying Pauli spin blockade using deep learning
Authors: Ares Natalia , Schuff Jonas , Lennon Dominic , Geyer S. , Craig David , Fedele Federico , Vigneau Florian , Camenzind Leon , Kuhlmann Andreas , Briggs Andrew , Zumbuhl Dominik , Sejdinovic Dino 
Published: June 2022

Abstract
Pauli spin blockade (PSB) can be employed as a great resource for spin qubit initialisation and readout even at elevated temperatures but it can be difficult to identify. We present a machine learning algorithm capable of automatically identifying PSB using charge transport measurements. The scarcity of PSB data is circumvented by training the algorithm with simulated data and by using cross-device validation. We demonstrate our approach on a silicon field-effect transistor device and report an accuracy of 96% on different test devices, giving evidence that the approach is robust to device variability. The approach is expected to be employable across all types of quantum dot devices.
Bile Microbiome in Patients with Recurrent Common Bile Duct Stones and correlation with the Duodenal Microbiome
Authors: Lee Jungnam , Park Jin-Seok , Bae Jaewoong , Lee Sohee , Hwang Yeonju 
Published: June 2022

Abstract
Background
Common bile duct (CBD) stone recurrence is a common late adverse event after CBD stone treatment. In this preliminary study, we compared the bile fluid and duodenum microbial profiles of patients with or without recurrent CBD stones to identify risk factors associated with recurrence.
Methods
Bile fluid samples of 47 consecutive patients who underwent ERCP for biliary diseases were subjected to microbiome analysis. Nineteen patients were stone recurrent (SR), and 28 patients were non-stone recurrent (NSR). Paired samples (duodenum biopsy tissue and bile fluid samples) from 5 SR patients were used to compare microbiome compositions in the biliary system and duodenum. In addition, we compared the microbiome compositions of these duodenal tissue samples with those 12 controls (gastric ulcer patients without recurrent CBD stones).
Results
Enterococcaceae_unclassified and enterococcus were more abundant in bile fluid in the SR group than in the NSR group (p = 0.002 and p = 0.003, respectively). A comparison of the microbiome compositions of duodenum tissue and bile fluid samples of the 5 recurrent CBD stone patients revealed proteobacteria compositions were almost identical from the phylum to genus level. In these 5 patients, alpha and beta diversities were no different in bile fluid and duodenal tissues. Furthermore, a comparison of the microbiome compositions of duodenal mucosa in patients with recurrent CBD stone patients (n = 5) and controls (n = 12) revealed significant differences between microbiome compositions.
Conclusions
Enterococcus seems to contribute to CBD stone development. Furthermore, our results indicate retrograde migration of the duodenal microbiome may contribute to bile microbiome alterations. We recommend that more research be conducted to confirm this hypothesis.
Racial/Ethnic and Income Disparities in Neighborhood-Level Broadband Access in 766 US Cities, 2017- 2019
Authors: Li Yuruo , Spoer Benjamin R. , Lampe Taylor , Hsieh Pei Yang , Nelson Isabel S. , Thorpe Lorna E. , Gourevitch Marc N. 
Published: June 2022

Abstract
Broadband access is an essential social determinant of health, the importance of which has increased due to the ongoing COVID-19 outbreak. Using data from the City Health Dashboard and American Community Survey, we found that in 2017, 30% of urban households in 766 large US cities still had no access to high-speed broadband internet. After controlling for household income, broadband access in majority Black and Hispanic neighborhoods was 10-15% lower than in White or Asian majority neighborhoods. In 2019, lack of broadband access in urban households decreased to 28%, but substantial broadband disparities still persist in these cities.
Microbial community in resistant and susceptible Churra sheep infected by Teladorsagia circumcincta
Authors: de Agüero Verónica Castilla Gómez , Esteban-Blanco Cristina , Argüello Héctor , Valderas-García Elora , Andrés Sonia , Arranz Juan José , Gutiérrez-Gil Beatriz , Martínez-Valladares María 
Published: June 2022

Abstract
Gastrointestinal nematodes (GIN) are a major threat to health and welfare in small ruminants worldwide. Teladorsagia circumcincta is a nematode that inhabits the abomasum of sheep, especially in temperate regions, causing important economic losses. Given that T. circumcincta and microbiome share the same niche, interactions between them and the host are expected. Although it is known that within a sheep breed there are animals that are more resistant than others to infection by GIN, it is not known if the microbiome influences the phenotype of these animals. Under this condition, 12 sheep were classified according to their cumulative faecal egg count (cFEC) at the end of a first experimental infection, 6 as resistant group (RG) and 6 as susceptible group (SG) to T. circumcincta infection. Then, all sheep were experimentally infected with 70,000 L3 of T. circumcincta and at day 7 days post-infection were euthanized. At necropsy, gastric mucosa and gastric content from abomasum were collected to extract bacterial DNA and sequence V3-V4 region from 16S rRNA gene using Ilumina technology. After bioanalysis performed, results showed that α-diversity and β-diversity remained similar in both groups. However, resistant phenotype sheep showed a higher number of bacteria butyrate-fermenting species as Clostridium sensu stricto-1 (abundance in RG: 1.29% and in SG: 0.069%; p = 0.05), and Turicibacter (abundance in RG: 0.31% and in SG: 0.027%;p = 0.07) in gastric content but also Serratia spp in gastric mucosa (abundance in RG: 0.12% and in SG: 0.041%; p = 0.07). A trend towards a significant negative correlation between cFEC and Clostridium sensu stricto-1 abundance in gastric content was detected (r = -0.537; p = 0.08). These data suggest that microbiome composition could be another factor that influence in the development of the resistant phenotype modifying the interaction with the host and the in last instance affecting the individual risk of infection.
Research on Competition and Cooperation of Central Ports in the Guangdong-Hong Kong-Macao Greater Bay Area Based on the Multi-group Lotka-Volterra Model
Authors: Wang Xuanfei , Liang Shan , Liao Zhenjie 
Published: June 2022

Abstract
The construction of the Guangdong-Hong Kong-Macao Greater Bay Area requires the establishment of a comprehensive port cooperation mechanism. Coordination is key to port integration. This paper establishes a multi-group Lotka-Volterra model based on the theory of competition and cooperation to study the evolution of the relationships among Hong Kong Port, Shenzhen Port, and Guangzhou Port. The results show that the three major ports have predator-prey roles and form a symbiotic competition and cooperation ecological pattern. The extended Hotelling model is established to study the central ports’ spatial differences; the results show that whether it is the central port cooperation body or the entire central port group, the gains from Shenzhen Port–Guangzhou Port cooperation are greater than between either and Hong Kong Port for Guangdong-Hong Kong-Macao Greater Bay Area’s container business. The biggest competitor to Hong Kong Port in the container business is Guangzhou Port. Hong Kong Port will gain more from cooperation with Shenzhen Port and should strengthen such cooperation. The study provides quantitative support and reference for positioning the strategic development of the high-end shipping business in Hong Kong Port, the pilot free-trade port in Shenzhen Port, and the exploration of the Shenzhen-Hong Kong composite port, Guangzhou Port’s comprehensive shipping hub.
The influence of a coupling nonlinear spring-mass system on dynamic responses of a generally restrained double-beam structure
Authors: Zhao Yuhao , Du Jingtao , Chen Yilin , Liu Yang 
Published: June 2022

Abstract
On various engineering occasions, complex structures are typically simplified as several-beam structures jointed by coupling devices. Coupling devices can be divided into rigid and elastic coupling cases. The elastic coupling device is regarded as a spring-mass system. When the coupling device is high-elastic, the equivalent stiffness of the elastic coupling device exhibits nonlinear characteristics. The existing studies related to double-beam structures are mainly limited to the linear case. There are few studies investigating the dynamic responses of the double-beam structure jointed by a nonlinear spring-mass system. Considering the engineering practice, this study establishes the vibration analysis model of a generally restrained double-beam structure coupled with a nonlinear spring-mass system. The governing equations of the double-beam structure and the coupling nonlinear spring-mass system are derived through the generalized Hamiltonian principle and the variational procedure. The Galerkin truncation method (GTM) is employed to predict the dynamic response of such a double-beam structure. On this basis, the influence of the coupling nonlinear spring-mass system on dynamic responses of the double-beam structure is investigated. It can be concluded that the GTM has good stability and correctness for predicting dynamic responses of the double-beam structure with a coupling nonlinear spring-mass system. Dynamic responses of such a double-beam structure are sensitive to their initial calculation values. Suitable coupling nonlinear stiffness beneficially influences vibration suppression and significantly changes the kinetic energy transfer characteristics of the double-beam structure. Additionally, single-frequency responses can be transferred into multi-frequency responses under a suitable coupling nonlinear stiffness.
Comprehensive analysis of survival related ceRNA regulatory net- work in Cholangiocarcinoma
Authors: Gao Xiaoling , Zhang Wenhao , Jia Yanjuan , Xu Hui , Zhu Yuchen , Pei Xiong 
Published: June 2022

Abstract
Background: Cholangiocarcinoma (CCA) is a highly malignant disease with poor prognosis. Its occurrence and development mechanisms remain unearthed. The ceRNA network describes the relationship between cancer-related RNAs and reveals the potential regulatory mechanism in CCA pathogenesis. Method: The genome transcriptome dataset of CCA was downloaded from the TCGA database. Differential expressional and survival analysis were performed by "edgeR" and "survival" package in R soft (|logFC|≥2, adjusted P-value<0.05), respectively. The interaction of miRNA-lncRNA and miRNA-mRNA were predicted by the miRanda and TargetScan. The ceRNA networks were visualized by the cytoscape 3.7. The heat maps, PCA analysis, KEGG and GO enrichment analysis, and prognostic model were performed and visualized on the online platform. Result: 6837 DEmRNAs, 2771 DElncRNAs, and 173 DEmiRNAs were screened out and ceRNA was constructed consisting of 434 lncRNA-miRNA pairs and 284 miRNA-mRNA pairs with 200 lncRNAs, 21 miRNAs and 245 mRNAs. Moreover, 3 lncRNAs (AC090772.1, LINC00519 and THAP7-AS1) and their downstream mRNAs (MECOM, MBNL3, RCN2) were significantly related to survival time. Finally, four key networks associated with survival-related DElncRNAs and DEmRNAs (LINC00519/hsa-mir-22/MECOM, THAP7-AS1/hsa-mir-429/MBNL3, THAP7-AS1/hsa-mir-155/MBNL3 and THAP7-AS1/hsa-mir-155/RCN2) were obtained. The disease-specific survival (DSS) prognostic model was established and showed the predictive ability based on these candidate ceRNA networks (AUC=0.66~0.83). Conclusion: The study provided a novel ceRNA network related to survival time that had broaden our understanding of the regulatory mechanisms in the development of CCA, as well as served as potential targets for drug development to improve the prognosis of CCA.