bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive responses of aroma production in ‘Benihoppe’ strawberry to low oxygen associated with the changes of key gene expressions and energy levels
Authors: Chen Jingxin , Zhang Demei , Zhang Xiaohan , Feng Xuqiao , Mi Hongbo , Ge Yonghong , Lv Jingyi 
Published: October 2022

AbstractBACKGROUNDThe influence of low oxygen on the biosynthesis of aroma‐related esters and alcohols in strawberries has been well revealed. However, how low‐oxygen conditions affect other volatile compounds, such as terpenes and furans, is still to be elucidated.RESULTSThe effects of 2 kPa O2 low oxygen on the biosynthesis of aroma in ‘Benihoppe’ strawberries were comprehensively investigated in this study. The results showed that, like esters, the accumulations of key terpene alcohols and furans in strawberries were also inhibited by 2 kPa O2 low oxygen during storage and subsequent shelf life, which was associated with the down‐regulation of expression of FaNES1 (nerolidol synthase) and FaOMT (O‐methyltransferase). However, no anaerobic fermentation occurred in ‘Benihoppe’ strawberries since no ethanol and acetaldehyde were produced under the 2 kPa O2 condition. As expected, the 2 kPa O2 condition suppressed the respiratory intensity and lowered the energy charge to maintain the quality of strawberries. The negative effects of low‐oxygen storage on aroma accumulations and the energy charge of strawberries were more pronounced when transferred to the period of shelf life.CONCLUSIONThe 2 kPa O2 condition caused a full‐scale loss of aroma in ‘Benihoppe’ strawberries, including esters and alcohols as well as terpenes and furans, which was mainly reflected in the reduction of aroma emissions rather than the production of off‐flavor, probably due to the reduced expressions of related genes and energy charge. © 2022 Society of Chemical Industry.
Same family, same mutation, different ECG
Authors: Akbuğa Kürşat , Karanfil Mustafa 
Published: October 2022

AbstractBackgroundDifferent types of long QT syndromes (LQTS) have distinct ECG manifestations according to the type and magnitude of ion channel dysfunction. While LQT1 carriers usually have broad‐based T waves and LQT3 carriers have extended ST segments with relatively narrow peaked T waves; LQT2 carriers have low‐amplitude T waves with high incidences of notches.MethodsWe describe three members of a family with the same LQTS2 pathogenic variant, but different surface ECG findings.ConclusionThis case shows ECG differences may also occur between family members who have pathogenic variants associated with long QT syndrome.
Prevalence of depressive symptoms and associated factors among foreign caregivers: A cross‐sectional study
Authors: Su Hsuan‐Cheng , Hu Sophia H. , Chi Mei‐Ju , Lin Yen‐Kuang , Wang Chih‐Yu , Nguyen Trung V. , Chuang Yeu‐Hui 
Published: October 2022

AbstractAimTo understand the prevalence of depressive symptoms among foreign caregivers and the associated factors.DesignA cross‐sectional study.MethodsData from 178 Indonesian foreign caregivers, selected based on convenience and snowball sampling in Taiwan, were collected between July 2019 and February 2020 using questionnaires. Stepwise multiple linear regression was used to identify the factors associated with depressive symptoms.ResultsApproximately 30.3% of the foreign caregivers displayed depressive symptoms. The symptoms were more prevalent among the participants who were younger; had more social support; shared a bed with others; and experienced higher work‐related stress, more loneliness and physical discomfort. The findings suggest that nurses or nurse practitioners visiting patients at home should not only deliver care for them but also show concern for the psychological well‐being of the foreign caregivers of these patients. Moreover, interventions should be developed to alleviate or prevent the emergence of depressive symptoms among foreign caregivers.
A systematic review study on the factors affecting shortage of nursing workforce in the hospitals
Authors: Tamata Adel Tutuo , Mohammadnezhad Masoud 
Published: October 2022

AbstractAimThis study aimed to determine factors that influence the nursing workforce shortage and their impact on nurses.DesignThis study applied a systematic review design.MethodsUsing Cochrane library guidelines, five electronic databases were systematically searched (Research 4life—PubMed/Medline, Scopus, Embase, CINAHL) from 2010–2021. The remaining articles with pertinent information were presented in a data extraction sheet for further thematic analysis. A Reporting Items for Systematic Reviews and Meta‐Analysis Flow Diagram was adopted and used. The studies published from 2010–2021 and in English language were examined and included in the systematic review.ResultsFour themes were identified as factors influencing the nursing workforce shortage, including Policy and planning barriers, Barriers to training and enrolment, Factors causing nursing staff turnover and Nurses' stress and burnout. Nursing workforce shortage is a global challenge that roots in multiple causes such as individual, educational, organizational and managerial and policy‐making factors.
Norwegian nursing students' experience during clinical placement in an African country: Communication, relationship building and nursing identity. A qualitative study
Authors: Greaker Tove Kristin , Grudt Solveig Kirsti , Aune Ingvild 
Published: October 2022

AbstractAimThe aim of this study was to gain a deeper understanding of the experience of Norwegian bachelor nursing students during clinical placement in an African country, with a focus on communication, relationship building and nurse identity.DesignExplorative, qualitative methods were used.MethodsThe data consisted of individual written reflection notes from 8 students' clinical placement in Africa, and transcripts from one semi‐structured focus group interview. The materials were analysed with systematic text condensation.ResultsThe students described their experience with the community of practice as challenging and enlightening. They found themselves in contexts where communication and language problems occurred. The students described how important relationships were for their practical training, and how this helped shape their nursing identity.
Electromagnetic interference shielding effectiveness of compression molded carbon nanofiber‐reinforced polyvinylidene difluoride film
Authors: Serrato Veronica M. , Padilla Victoria , Jones Daniel , Herrera Sergio , Campos Luis , Serrato Ignacio , Foltz Heinrich , Lozano Karen 
Published: October 2022

AbstractIn this study, vapor grown carbon nanofiber (VGCNF) reinforced polyvinylidene difluoride (PVDF) composites were developed. Composites were fabricated by high shear mixing using a Banbury type mixer. The material was then subjected to compression molding resulting in films with an average thickness of 0.82 mm. The developed films were subjected to physico‐thermal, and electrical characterization including analysis of the shielding effectiveness (SE) of electromagnetic interference (EMI). Morphological analysis was conducted by scanning electron microscopy and characterization complemented with Fourier transform infrared spectroscopic and X‐ray diffraction analyses. The thermal properties were studied by differential scanning calorimetry and thermogravimetric analysis, which revealed the influence of carbon nanofibers on thermal stability and phase transitions. The electrical conductivity for in‐plane and through‐plane was gradually enhanced by increasing the concentration of VGCF loading; a percolation threshold was initiated at 5 wt% loadings. In plane and through plane resistivity decreased from 1011 Ω‐cm to 103 Ω‐cm and 102 Ω‐cm, respectively. An in‐depth EMI SE study was conducted depicting the influence of VGCNFs on skin depth, EMI power coefficients for reflection, absorption and transmission, and EMI SE for reflection, absorption, and total. The total SE of the developed nanocomposite films was observed to range between 6.6–16.4 dB in a frequency range of 30 kHz to 1.5 GHz. This study presents the processing‐structure–property relationships for lightweight and flexible NC films with enhanced electrical conductivity.
HDOCK update for modeling protein‐RNA/DNA complex structures
Authors: Li Hao , Huang Eddie , Zhang Yi , Huang Sheng‐You , Xiao Yi 
Published: October 2022

AbstractProtein‐nucleic acid interactions are involved in various cellular processes. Therefore, determining the structures of protein‐nucleic acid complexes can provide insights into the mechanisms of the interactions and thus guide the rational drug design to modulate these interactions. Due to the high cost and technical difficulties of solving complex structures experimentally, computational modeling such as molecular docking has been playing an important role in the study of molecular interactions. In order to make it easier for researchers to obtain biomolecular complex structures through molecular docking, we developed the HDOCK server for protein–protein and protein–RNA/DNA docking (accessed at http://hdock.phys.hust.edu.cn/). Since its first release in 2017, HDOCK has been widely used in the scientific community. As nucleic acids may include single‐stranded (ss) RNA/DNA and double‐stranded (ds) RNA/DNA, we now present an updated version of HDOCK, which offers new options for structural modeling of ssRNA, ssDNA, dsRNA, and dsDNA. We hope this update will better help the scientific community solve important biological problems, thereby advancing the field. In this article, we describe the general protocol of HDOCK with emphasis on the new functions on RNA/DNA modeling. Several application examples are also given to illustrate the usage of the new functions.
On the stochastic finite‐time stability for switched stochastic nonlinear systems
Authors: Hu Wei , Zhu Quanxin 
Published: October 2022

AbstractIn this paper, the stochastic finite‐time stability (SFTS) criteria for switched stochastic nonlinear systems (SSNS) with nonlocal Lipschitz coefficients are established. The main tools that we used here are mode‐dependent limiting average dwell time (MD‐LADT), stopping time technology and the stochastic analysis theory. The established criteria show that the diffusion coefficient, the drift coefficient and the switching law play crucial roles in obtaining the SFTS for the SSNS. Besides, our criteria provide some approaches on how to design the switching law to achieve the SFTS if a switched stochastic system contains SFTS subsystems and stochastic finite‐time instable (SFTI) subsystems simultaneously. Finally, an example is given to illustrate the importance and usefulness of the theoretical results.
A biomimetic systems method to organizational sustainable development and harmony: The Zen Business Model
Authors: Coll Josep M. 
Published: October 2022

AbstractIn a global knowledge and socioeconomic system dominated by the Western worldview, this paper introduces, from a practical point of view, the Zen Business Model. This is an emerging systems approach grounded on ancient Eastern wisdom that explores the symbiotic relationship between Taoism and Buddhism applied to organizational sustainable development and transformation. The model brings a universal and natural understanding of the organization as a living system whose value generating behaviour biomimics the natural cycles of transformation explained in Taoist systems theories. By doing so, the paper argues, on one hand, that business organizations can learn from nature‐based Eastern systems approaches as a way to increase their positive contribution to society, the environment and the economy. And, on the other hand, it explains the five corporate stars and its value dynamics as a principles‐based pathway to sustainable transformation.
XAV‐939 inhibits epithelial‐mesenchymal transformation in pulmonary fibrosis induced by crystalline silica via the Wnt signaling pathway
Authors: Lv Zhihao , Xu Hao , Si Xuezhe , Xu Shushuo , Li Xinxiao , Li Ning , Zhou Qiang , Chang Meiyu , Yao Sanqiao , Li Haibin 
Published: October 2022

AbstractSilicosis is an occupational lung disease that results from long‐term inhalation of free silica dust, the expression is sustained inflammation response, fibroblast hyperplasia, and excessive collagen deposit, bringing about pulmonary interstitial fibrosis. Wnt signaling pathway exists in various kinds of eukaryotic cells, is a highly conservative signaling pathway in biological evolution, and participates in cell proliferation, differentiation, migration, and polarity of physiological activity, such as in embryonic development, organ morphology, and tumor. In addition, it plays an important role in the progress of fibrosis disease. At present, studies related to silicosis are increasing, but the pathogenesis of silicosis still is not clear. In recent years, more and more studies have suggested that the Wnt signaling pathway could participate in the pathogenesis of silicosis fibrosis. In the study, we explored the mechanism of the Wnt signaling pathway in the pathogenesis of silicosis fibrosis and evaluated the effect of XAV‐939 treatment epithelial‐mesenchymal transformation (EMT) induced by silica. In addition, the results showed that EMT and activation of the Wnt signaling pathway would occur after stimulation of silica or TGF‐β1. However, after treatment with the Wnt signaling pathway inhibitor XAV‐939, EMT was reversed and the expression of the β‐catenin decreased. These results suggested that the Wnt signaling pathway is associated with EMT induced by silica and it could be a potential target for the treatment of silicosis.
Validation of the Burden Transfer Inventory‐abbreviated and examination across veterinary medicine positions and settings in the United States
Authors: Spitznagel Mary B. , Martin John T. , Carlson Mark D. , Fulkerson Christopher M. 
Published: October 2022

AbstractBackgroundBurden transfer, when veterinary client caregiver burden underlies stressful encounters with providers, elevates risk for occupational distress in veterinary medicine. To date, burden transfer has been primarily examined in veterinarians working in general practice, using methods that are time consuming. The current work validates an abbreviated Burden Transfer Inventory (BTI‐A) and explores burden transfer across positions of employment and veterinary settings.MethodsParticipants completed online measures of burden transfer, stress and burnout. A BTI‐A with items representing each BTI domain was created with an initial validation sample (n = 1151 veterinarians). Confirmatory psychometric analyses were conducted in a cross‐validation sample (n = 440 veterinarians and support staff), followed by exploration of the BTI and BTI‐A across veterinary settings and position of employment.ResultsThe BTI‐A correlated with the full‐length BTI (r = 0.89–0.96) shows good internal consistency (α = 0.72–0.88) and 1‐month test–retest reliability (r = 0.69–0.74). The BTI‐A correlated significantly (p < 0.001) with stress and burnout. Exploratory comparisons suggested group differences including greater reactivity in general compared to specialty referral/emergency practice (p = 0.02).ConclusionThe BTI‐A can be used in place of the original measure when brevity is important. Use of the BTI‐A may help guide allied mental health professionals in providing support for wellbeing in veterinary healthcare team members.
Carcinosarcoma of the nasal cavity and paranasal sinuses: Review of the national cancer database
Authors: Harris Jacob C. , Eide Jacob G. , Kshirsagar Rijul S. , Brant Jason A. , Palmer James N. , Adappa Nithin D. 
Published: October 2022

AbstractBackgroundCarcinosarcomas are rare, aggressive malignancies that can arise in the nasal cavity and paranasal sinuses. There are limited outcome data available. Accordingly, we sought to use the National Cancer Database (NCDB) to characterize patient demographics and outcomes.MethodA retrospective analysis of the NCDB from 2004 to 2016 for patients with sinonasal carcinosarcoma was conducted.ResultsThirty patients were included. The patients were predominantly male (n = 20), white (n = 23), and privately insured (n = 15), with an average age of 62.4 years. The nasal cavity was the most common subsite (n = 14), followed by the maxillary sinus (n = 8). Most patient were treated with surgery followed by radiation (n = 23), with the remaining undergoing surgery alone (n = 4), radiation alone (n = 2), or no treatment (n = 1). One‐third (n = 10) received adjuvant chemotherapy. The 1‐ and 5‐year overall survival (OS) in the cohort were 79.2% and 43.3%, respectively. Univariate log‐rank testing showed OS varied based on intervention (P < 0.029), sex (P < 0.042), and age (P < 0.025), while on multivariate analysis none of these factors independently predicted OS.ConclusionsWe describe the demographics and presenting features of a national cohort of sinonasal carcinosarcoma patients. Future research is needed to identify predictors of overall survival, and to assess the optimal roles for radiation and systemic chemotherapy.
Virtual Reality (VR) in Anatomy Teaching and Learning in Higher Healthcare Education
Authors: Aasekjær K. , Gjesdal B. , Rosenberg I. , Bovim L. P. 
Published: October 2022

AbstractThis chapter provides information for teachers in higher education who are interested in collaborative learning combined with the use of immersive virtual reality (VR). It presents an introduction to VR and experiences from implementing and using VR in training midwifery students on the master’s level and radiography students in anatomy on the bachelor’s level.
Playful Learning with VR-SIMI Model: The Use of 360-Video as a Learning Tool for Nursing Students in a Psychiatric Simulation Setting
Authors: Haugan Siri , Kværnø Eivind , Sandaker Johnny , Hustad Jonas Langset , Thordarson Gunnar Orn 
Published: October 2022

AbstractEducational institutions can elevate student perspective and activation so that playful learning is formed by looking for new teaching possibilities. Didactical methods need to provide a safe environment where students can focus on interpersonal interactions with patients while being aware of how their own emotions can influence their situational awareness and decisions. The authors believe that relevant scenarios in a 360-degree video format will be beneficial for nursing students, specifically in preparation for the clinical setting. The potential of 360-degree video in virtual reality (VR) gives the instructor flexibility to create systematic, experiential learning and shapes emotional learning in collaboration with students. 360-Degree video can be seen as a playful way to learn in new situations. Playfulness of this kind can affect teachers and students motivation, as well as the opportunity to promote learning. This field lacks studies exploring the use of 360-degree videos in psychiatric simulation settings. This chapter will provide knowledge about the practical use of 360-degree video in VR, insight into technical potential, as well as challenges. Background information on why this method is suitable for promoting nursing students’ competence in mental health work will be presented. Another function of this chapter is to give an introduction and inspire exploration of 360-degree video in VR in professional education, with particular focus on how this can be used as a tool for nursing students in psychiatric simulation settings, like the VR-SIMI model, which is discussed later in the chapter.
Locality and analyticity of the crossing symmetric dispersion relation
Authors: Chowdhury Debapriyo , Haldar Parthiv , Zahed Ahmadullah 
Published: October 2022

Abstract
This paper discusses the locality and analyticity of the crossing symmetric dispersion relation (CSDR). Imposing locality constraints on the CSDR gives rise to a local and fully crossing symmetric expansion of scattering amplitudes, dubbed as Feynman block expansion. A general formula is provided for the contact terms that emerge from the expansion. The analyticity domain of the expansion is also derived analogously to the Lehmann-Martin ellipse. Our observation of type-II super-string tree amplitude suggests that the Feynman block expansion has a bigger analyticity domain and better convergence.
Zum Verzehr ungeeignete Botanicals wie Cannabis und Kurkuma in Lebensmitteln – Anwendung des § 12 LFGB in Abgrenzung von Artikel 14 der Basis-Verordnung
Authors: Beisel Julia M. , Schaumann Theresa , Bock Verena , Rajcic de Rezende Tabata , Sproll Constanze , Walch Stephan G. , Lachenmeier Dirk W. 
Published: October 2022

AbstractThe assessment of foods containing botanicals above toxicological thresholds poses challenges, as administrative court decisions have set high barriers for the application of Art. 14 para. 2a or 2b of the General Food Law Regulation (EC) No 178/2002. If the application of Art. 14 para. 2b of the General Regulation is restricted by a narrow interpretation of para. 5 to contamination, putrefaction, spoilage or decomposition, a regulatory loophole emerges. The examples of tetrahydrocannabinol in hemp products with cannabidiol and curcumin in food supplements with turmeric illustrate the challenge of food regulatory evaluation, as there is no contamination by definition in the products mentioned. In such cases, where Art. 14 of the General Regulation cannot be applied, an assessment as unfit for consumption according to § 12 food and feed law (LFGB) has to be considered. The legal basis transferred to German national § 12 LFGB was historically used for the assessment of so-called disgust cases. However, § 12 LFGB is not explicitly limited to these, but is openly formulated for cases that are not subject to Art. 14 of the General Regulation. Accordingly, in the opinion of the authors, a food regulatory assessment of products containing botanicals that exceed toxicological threshold values is possible under § 12 LFGB.
Modelling the spatial distribution of the classification error of remote sensing data in cocoa agroforestry systems
Authors: Kanmegne Tamga Dan , Latifi Hooman , Ullmann Tobias , Baumhauer Roland , Thiel Michael , Bayala Jules 
Published: October 2022

AbstractCocoa growing is one of the main activities in humid West Africa, which is mainly grown in pure stands. It is the main driver of deforestation and encroachment in protected areas. Cocoa agroforestry systems which have been promoted to mitigate deforestation, needs to be accurately delineated to support a valid monitoring system. Therefore, the aim of this research is to model the spatial distribution of uncertainties in the classification cocoa agroforestry. The study was carried out in Côte d’Ivoire, close to the Taï National Park. The analysis followed three steps (i) image classification based on texture parameters and vegetation indices from Sentinel-1 and -2 data respectively, to train a random forest algorithm. A classified map with the associated probability maps was generated. (ii) Shannon entropy was calculated from the probability maps, to get the error maps at different thresholds (0.2, 0.3, 0.4 and 0.5). Then, (iii) the generated error maps were analysed using a Geographically Weighted Regression model to check for spatial autocorrelation. From the results, a producer accuracy (0.88) and a user’s accuracy (0.91) were obtained. A small threshold value overestimates the classification error, while a larger threshold will underestimate it. The optimal value was found to be between 0.3 and 0.4. There was no evidence of spatial autocorrelation except for a smaller threshold (0.2). The approach differentiated cocoa from other landcover and detected encroachment in forest. Even though some information was lost in the process, the method is effective for mapping cocoa plantations in Côte d’Ivoire.