bluuebunny/crossref_metadata_2025_split huggingface dataset:
Innovative financing of the sustainable development goals in the countries of the Western Balkans
Authors: Lukšić Igor , Bošković Bojana , Novikova Aleksandra , Vrbensky Rastislav 
Published: February 2022

AbstractBackgroundThis paper is related to the current stage of development in the Western Balkans. Despite becoming growing instruments to finance sustainable green development, debt swaps and social or sustainability bonds are relative novelties in this region. At the same time, the development needs are huge, especially in the light of the COVID-19 aftermath.ResultsThe review of both historic financial instruments, such as the debt for nature swaps, and more recent ones, such as sustainability bonds in its variations, highlight the potential for use in developing countries. The relatively recent case from Montenegro and the recent issuance of the green bond in Serbia showcase the possibilities. The focus of this paper is an analysis of the public debt position of Western Balkan countries. The growing level of public debt over the past decade points to a lack of adequate interventions and a relatively imminent need for fiscal consolidation. The research suggests that environmental, social, governance/sustainability-linked bonds and debt-for-climate swap investments as innovative financial instruments that hold promise in leveraging additional finance to support the sustainability goals of the six countries of the Western Balkans. This influx of capital would be particularly advantageous, given their needs relative to EU accession and their economic and structural challenges. The recommendations for policymakers are derived based on the history and features of green bonds as well as debt-for-nature swaps and their diverse underlying mechanisms which are adaptable to the respective countries.ConclusionsThe related countries would benefit from exploring more innovative approaches to finance sustainable societies. In close cooperation with the EU and taking the European Green Deal into consideration, it is recommended that the six countries of the Western Balkans design financing mechanisms that will bring increased transparency to the different policies and more accountability for their implementation. Applying the recommended modality may help keep the problem of the public debt at bay, while additional funds may support implementation of structural reforms.
Adapted remote cognitive behavioural therapy for comfort eating with a woman with intellectual disabilities: Case report
Authors: Millar Chris , Greenhill Beth 
Published: February 2022

AbstractBackgroundDiagnostic overshadowing can prevent the treatment of comfort eating in people with intellectual disabilities, and the published literature contains few therapeutic examples. This case study reports a relatively novel, promising, and accessible, remote cognitive behavioural intervention.Case presentationThis case study documents a therapeutic intervention for comfort eating with a client, Sarah, in a National Health Service adult Community Learning Disabilities Service. Sarah is a white, British woman in her late thirties, with a diagnosis of Down syndrome who experienced significant problems with comfort eating and subsequent weight management. Despite dieting and exercising, Sarah was clinically obese and experienced weight related pain and psychological distress. Systemic intervention between Sarah, her mother, and the therapist formulated Sarah’s eating difficulties using a cognitive behavioural framework. This hypothesised how comfort-eating met her emotional needs and maintained her health difficulties. Remote cognitive behavioural therapy interventions included collaborative behavioural experiments, coping strategies, and homework tasks.ConclusionsThe Maslow Assessment of Needs Scale-Learning Disabilities, Glasgow Depression Scale for people with a Learning Disability, Glasgow Anxiety Scale for people with an Intellectual Disability, qualitative feedback from family, as well as frequency data showed significant improvement. Additionally, the case considers the evidence base, assessment, formulation and intervention, before reflecting on its various strengths and limitations. It reflects on the intersectionality of sexuality and intellectual disabilities, and the desire for romantic attachment, which was additionally complicated by the context of coronavirus and social isolation. The environmental influences on comfort eating regarding this case, and in general, the experiences of people with intellectual disabilities are also considered. The potential clinical impact of this case study includes exemplifying an effective comfort eating therapeutic intervention in an often overlooked client group.
Terrain traversability prediction for off-road vehicles based on multi-source transfer learning
Authors: Inotsume Hiroaki , Kubota Takashi 
Published: February 2022

AbstractIn this paper, a novel terrain traversability prediction method is proposed for new operation environments. When an off-road vehicle is operated on rough terrains or slopes made up of unconsolidated materials, it is crucial to accurately predict terrain traversability to ensure efficient operations and avoid critical mobility risks. However, the prediction of traversability in new environments is challenging, especially for possibly risky terrains, because the traverse data available for such terrains is either limited or non-existent. To address this limitation, this study proposes an adaptive terrain traversability prediction method based on multi-source transfer Gaussian process regression. The proposed method utilizes the limited data available on low-risk terrains of the target environment to enhance the prediction accuracy on untraversed, possibly higher-risk terrains by leveraging past traverse experiences on multiple types of terrain surface. The effectiveness of the proposed method is demonstrated in scenarios where vehicle slippage and power consumption are predicted using a dataset of various terrain surfaces and geometries. In addition to predicting terrain traversability as continuous values, the utility of the proposed method is demonstrated in binary risk level classification of yet to be traversed steep terrains from limited data on safer terrains.
Genetic regulation of the ompX porin of Salmonella Typhimurium in response to hydrogen peroxide stress
Authors: Briones A. C. , Lorca D. , Cofre A. , Cabezas C. E. , Krüger G. I. , Pardo-Esté C. , Baquedano M. S. , Salinas C. R. , Espinoza M. , Castro-Severyn J. , Remonsellez F. , Hidalgo A. A. , Morales E. H. , Saavedra C. P. 
Published: February 2022

Abstract
Background
Salmonella Typhimurium is a Gram-negative pathogen that causes a systemic disease in mice resembling typhoid fever. During its infective cycle, S. Typhimurium is phagocytized by macrophages and proliferates inside a Salmonella-containing vacuole where Salmonella is exposed and survives oxidative stress induced by H2O2 through modulation of gene expression. After exposure of Salmonella to H2O2, the expression of the porin-encoding gene ompX increases, as previously shown by microarray analysis. Expression of ompX mRNA is regulated at a post-transcriptional level by MicA and CyaR sRNAs in aerobiosis. In addition, sequence analysis predicts a site for OxyS sRNA in ompX mRNA.

Results
In this work we sought to evaluate the transcriptional and post-transcriptional regulation of ompX under H2O2 stress. We demonstrate that ompX expression is induced at the transcriptional level in S. Typhimurium under such conditions. Unexpectedly, an increase in ompX gene transcript and promoter activity after challenges with H2O2 does not translate into increased protein levels in the wild-type strain, suggesting that ompX mRNA is also regulated at a post-transcriptional level, at least under oxidative stress. In silico gene sequence analysis predicted that sRNAs CyaR, MicA, and OxyS could regulate ompX mRNA levels. Using rifampicin to inhibit mRNA expression, we show that the sRNAs (MicA, CyaR and OxyS) and the sRNA:mRNA chaperone Hfq positively modulate ompX mRNA levels under H2O2-induced stress in Salmonella during the exponential growth phase in Lennox broth.

Conclusions
Our results demonstrate that ompX mRNA is regulated in response to H2O2 by the sRNAs CyaR, MicA and OxyS is Salmonella Typhimurium.
Body Fat of Basketball Players: A Systematic Review and Meta-Analysis
Authors: Sansone Pierpaolo , Makivic Bojan , Csapo Robert , Hume Patria , Martínez-Rodríguez Alejandro , Bauer Pascal 
Published: February 2022

Abstract
Background
This study aimed to provide reference values for body fat (BF) of basketball players considering sex, measurement method, and competitive level.

Methods
A systematic literature research was conducted using five electronic databases (PubMed, Web of Science, SPORTDiscus, CINAHL, Scopus). BF values were extracted, with analyses conducted using random-effects models and data reported as percentages with 95% confidence intervals (CI).

Results
After screening, 80 articles representing 4335 basketball players were selected. Pooled mean BF was 13.1% (95% CI 12.4–13.8%) for male players and 20.7% (95% CI 19.9–21.5%) for female players. Pooled mean BF was 21.4% (95% CI 18.4–24.3%) measured by dual-energy X-ray absorptiometry (DXA), 15.2% (95% CI 12.8–17.6%) via bioelectrical impedance analysis (BIA), 12.4% (95% CI 10.6–14.2%) via skinfolds and 20.0% (95% CI 13.4–26.6%) via air displacement plethysmography. Pooled mean BF across competitive levels were 13.5% (95% CI 11.6–15.3%) for international, 15.7% (95% CI 14.2–17.2%) for national and 15.1% (95% CI 13.5–16.7%) for regional-level players. As the meta-regression revealed significant effects of sex, measurement method and competitive level on BF, the meta-analysis was adjusted for these moderators. The final model revealed significant differences in BF between male and female players (p < 0.001). BF measured by DXA was significantly higher than that measured by BIA or skinfolds (p < 0.001). International-level players had significantly lower BF than national and regional-level players (p < 0.05).

Conclusions
Despite the limitations of published data, this meta-analysis provides reference values for BF of basketball players. Sex, measurement method and competitive level influence BF values, and therefore must be taken into account when interpreting results.
COVID-19 and the expanding role of international urban search and rescue (USAR) teams: the case of the 2020 Beirut explosions
Authors: Okita Yosuke , Glassey Steve , Shaw Rajib 
Published: February 2022

AbstractThe paper conducts a case study on the international urban search and rescue (USAR) response to the Beirut explosions in August 2020. The incident is worth analysing because it was the first of the international USAR deployments under global travel restrictions arising from the COVID-19 pandemic. It will closely look at the activity of @fire Germany, which is self-recognised as a light USAR team, deployed to Beirut. Due to the arrangements imposed for COVID-19 prevention, it becomes more difficult for international USAR teams to arrive in affected areas quickly, meaning that the possibility for life-saving further decreases. Thus, international USAR teams must be flexible to contribute to early recovery activity after the completion of the search and rescue phase. The @fire Germany’s response gives a good example of how light international USAR teams could contribute to early recovery. Also, some countries might not want to receive or send international USAR teams due to the COVID-19 pandemic. In the COVID-19 era, strengthening national and local teams, or first responders, who are already in-country becomes critical to saving more lives.
Transcriptome sequencing reveals core regulation modules and gene signatures of Zusanli acupoints in response to different moxibustion warm stimulation in adjuvant arthritis rat
Authors: Zeng Li , Guo Jing , Du Ping , Yu Shuguang , Yin Haiyan 
Published: February 2022

Abstract
Background
The efficacy of moxibustion in treating rheumatoid arthritis is recognized, but its molecular mechanism is still unclear. This study aimed to characterize the molecular map and potential key genes in the process of different moxibustion warm at Zusanli acupoint treatment of adjuvant arthritis (AA) model.

Methods
AA rat model was induced by complete Freund’s adjuvant (CFA) and then accessed by foot swelling and thermal hyperalgesia test. Transcriptome sequencing, series test of cluster (STC) and weighted gene co-expression network analysis (WGCNA) were used in this study.

Results
CFA-induced inflammation, foot swelling, and pain in AA rats were significantly improved by moxibustion warm. Differentially expressed genes (DEGs) were screened in nine different comparison groups and a total of 4535 DEGs were identified, and these DEGs were preferentially clustered in inflammatory and immune-related pathways, such as MAPK signaling pathway. Only 1 DEG of heat shock protein 90, alpha (cytosolic), class A member 1 (Hsp90aa1) was shared in comparison groups of model with moxibustion treatment. STC analysis also revealed that Hsp90aa1 was increased in AA model, but decreased after 37 °C moxibustion intervention, and constantly decreased after 42 °C moxibustion treatment. GO and KEGG pathway analysis revealed that these genes enriched in inflammatory and immune-related pathways. Moreover, WGCNA identified that violet module was positively correlated with model temperature while negatively correlated with control, and the paleturquoise module was positively correlated with model. The violet and paleturquoise module gene were significantly enriched in MAPK signaling pathway. Importantly, Hsp90aa1 also played a central role in the violet module by interacting with multiple proteins.

Conclusions
Moxibustion warm improved AA in rat, and we obtained the transcriptome profile and excavate a critical gene of Hsp90aa1, and provided insight into gene signatures for moxibustion warm at Zusanli acupoint in AA rat.
Patients’ perspectives of telemedicine appointments for psoriatic arthritis during the COVID-19 pandemic: results of a patient-driven pilot survey
Authors: Jethwa Hannah , Brooke Melanie , Parkinson Andrew , Dures Emma , Gullick Nicola J. 
Published: February 2022

Abstract
Background
Over recent years the lack of patient involvement in the design, set-up and implementation of clinical research studies has been well recognised; as such there has been a drive within research communities to increase patient participation. Patient perspectives on telemedicine differ widely, with variation in whether patients feel remote consultations are beneficial. By means of a patient-driven survey, we aimed to formally evaluate patient perspectives on its benefits and pitfalls, focusing on patients with psoriatic arthritis (PsA).

Methods
An e-survey was developed by two patient representatives on the BritPACT steering committee, with a view to determining unmet needs and the perceived impact on clinical care of virtual consultations amongst patients with PsA.

Results
128 patients responded to the e-survey. 109 patients rated the effectiveness of their telemedicine appointment and, of these, 18% felt their virtual consultation was very/extremely effective compared to an in-clinic consultation and 49% felt it was somewhat/equally as effective; furthermore, 48% (51/107) felt that such virtual consultations would be of benefit to them after the pandemic. 36% of respondents felt their virtual consultation was not as effective as an in-clinic review. Themes identified from open-ended questions included the lack of visual cues, lack of physical examination and effect on rapport and ease of open communication as the main pitfalls of virtual consultations. Patients with well-controlled symptoms appeared more satisfied with remote reviews compared to those with active disease, though on the whole respondents recognised the benefits, such as saving travel time and costs. Those who had an established relationship with their health professional appeared less concerned regarding virtual consultations though a recurring view was that newly diagnosed patients should have in-clinic appointments to build rapport and improve symptom control at an early stage.

Conclusions
Overall patients’ perspectives on virtual consultations varied widely though patients with well-controlled symptoms and those who had a previously established relationship with their healthcare professionals and well-controlled disease appeared more satisfied with remote reviews.
Enhanced recovery after surgery for major orthopedic surgery: a narrative review
Authors: Choi Yun Seong , Kim Tae Woo , Chang Moon Jong , Kang Seung-Baik , Chang Chong Bum 
Published: February 2022

Abstract
Background
With increasing interest in enhanced recovery after surgery (ERAS), the literature on ERAS in orthopedic surgery is also rapidly accumulating. This review article aims to (1) summarize the components of the ERAS protocol applied to orthopedic surgery, (2) evaluate the outcomes of ERAS in orthopedic surgery, and (3) suggest practical strategies to implement the ERAS protocol successfully.

Main body
Overall, 17 components constituting the highly recommended ERAS protocol in orthopedic surgery were identified. In the preadmission period, preadmission counseling and the optimization of medical conditions were identified. In the preoperative period, avoidance of prolonged fasting, multimodal analgesia, and prevention of postoperative nausea and vomiting were identified. During the intraoperative period, anesthetic protocols, prevention of hypothermia, and fluid management, urinary catheterization, antimicrobial prophylaxis, blood conservation, local infiltration analgesia and local nerve block, and surgical factors were identified. In the postoperative period, early oral nutrition, thromboembolism prophylaxis, early mobilization, and discharge planning were identified. ERAS in orthopedic surgery reduced postoperative complications, hospital stay, and cost, and improved the patient outcomes and satisfaction with accelerated recovery. For successful implementation of the ERAS protocol, various strategies including the standardization of care system, multidisciplinary communication and collaboration, ERAS education, and continuous audit system are necessary.

Conclusion
The ERAS pathway enhanced patient recovery with a shortened length of stay, reduced postoperative complications, and improved patient outcomes and satisfaction. However, despite the significant progress in ERAS implementation in recent years, it has mainly focused on major surgeries such as arthroplasty. Therefore, further efforts to apply, audit, and optimize ERAS in various orthopedic surgeries are necessary.
Analysis of clinical and radiological outcomes of long tibial stemmed total knee arthroplasty in knee osteoarthritis complicated by tibial stress fracture
Authors: Reddy Neelam V. Ramana , Saini Mukesh Kumar , Reddy Pera Jayavardhan , Thakur Ajay Singh , Reddy Challa Dinesh 
Published: February 2022

Abstract
Objective
Knee arthritis associated with tibial stress fractures represents an uncommon and difficult clinical scenario to treat. The use of long, fluted tibial extension rods has been vital in the management of such cases owing to immediate fracture stability and single-stage surgery without the need to open the fracture site. This study investigates clinical and radiological outcomes following total knee arthroplasty using a tibial extension stem in cases of knee osteoarthritis with tibial stress fracture.

Methods
From February 2015 to December 2020, 17 patients who had total knee arthroplasty implanted with a long stemmed tibial component were included in the study. Patient data were analyzed for knee range of motion, deformities, Knee Society score, knee function score, and time to fracture union in the pre- and postoperative periods.

Results
The mean follow-up duration was 22.7 ± 11.68 months (range 12–60 months), and mean time to fracture healing was 10.23 ± 2.81 weeks (range 8–20 weeks). The preoperative mean fixed flexion deformity improved from 8.53 ± 3.43° to a mean of 0.29°, and knee flexion improved from 79.4 ± 13.90° to 125.29 ± 8.74° on postoperative assessment. The Knee Society score improved from a mean preoperative score of 18.94 ± 5.55 (range 8–28) to 89.41 ± 7.5 (range 74–102, p value < 0.001). Similarly, the knee function score improved significantly from a mean preoperative score of 15.5 ± 4.48 (range 8–26) to a mean of 85 ± 6.09 (range 72–94, p value < 0.001).

Conclusion
Total knee arthroplasty using long tibial extenders has been an effective and safe surgical option for patients with advanced osteoarthritis with tibial stress fractures.
Mechanical performance of strain-hardening cementitious composites (SHCC) with bacterial addition
Authors: Zhang Zhigang , Liu Dawei , Ding Yuanzhao , Wang Shuping 
Published: February 2022

AbstractIncorporation of bacteria can realize self-healing and enhance strength of concrete, which has been drawn extensive attention in past decades. The studies focused on the properties of fiber reinforced concrete with bacterial addition are still very limited. In this paper, mechanical performance of strain hardening cementitious composites (SHCC) with directly adding vegetative bacterial cells was investigated. The experimental results revealed that the compressive, first cracking, and tensile strength of SHCCs was increased due to the addition of bacteria, while the tensile strain capacity tended to decline. At micro-scale level, the matrix containing bacteria has relative higher fracture toughness to that of reference mix. Interestingly, the bacteria notably lowered chemical bond between PVA fiber and its surrounding hydrates; on the other hand, the frictional bond was enhanced. The findings in this study can provide a reference for modifying the surface of hydrophilic fibers.
Text-rating review discrepancy (TRRD): an integrative review and implications for research
Authors: Almansour Amal , Alotaibi Reem , Alharbi Hajar 
Published: February 2022

AbstractThe large number of online product and service review websites has created a substantial information resource for both individuals and businesses. Researching the abundance of text reviews can be a daunting task for both customers and business owners; however, rating scores are a concise form of evaluation. Traditionally, it is assumed that user sentiments, which are expressed in the text reviews, should correlate highly with their score ratings. To better understand this relationship, this study aims to determine whether text reviews are always consistent with the combined numeric evaluations. This paper reviews the relevant literature and discusses the methodologies used to analyse reviews, with suggestions of possible future research directions. From surveying the literature, it is concluded that the quality of the rating scores used for sentiment analysis models is questionable as it might not reflect the sentiment of the associated reviews texts. Therefore, it is suggested considering both types of sources, reviews’ texts and scores in developing Online Consumer Reviews (OCRs) solution models. In addition, quantifying the relationship degree between the text reviews and the scores might be used as an instrument to understand the quality of rating scores, hence its usefulness as labels for building OCRs solution models.