bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Foliar Application of Iron (Fe) and Zinc (Zn) on Growth, Yield and Quality of Strawberry (Fragaria ananassa) Cv. Winter Dawn
Authors: Bopparaju Aruna Kumari , Deepanshu . , Mishra Saket , Bahadur Vijay 
Published: October 2022

An experiment on strawberry (Fragaria ananassa) cv. winter dawn was conducted during December 2021 to April 2022, in Horticulture Research Farm of Horticulture Department, Naini Agricultural Institute, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj (U.P) India. The experiment was performed on strawberry variety of winter dawn. There are 16 treatments, viz., T0 (water spray),T1(Zn 0.2%+Fe 0.2%),T2 ( Zn 0.4%+Fe 0.4%),T3 ( Zn 0.6%+Fe 0.6%),T4(Zn 0.2%+Fe 0.4%),T5 (Zn 0.2%+Fe 0.6%)T6(Zn 0.4%+Fe 0.2%)T7 (Zn 0.4%+Fe 0.6%)T8(Zn 0.6%+Fe0.4%)T9(Zn 0.6%+Fe 0.2%) ,T10 (Zn 0.2%),T11(Zn 0.4%),T12(Zn 0.6%) ,T13(Fe 0.2%),T14 (Fe 0.4%),T15 (Fe 0.6%) replicated thrice in Randomized Block Design (RBD). The results of the present investigation, regarding the cultivation of strawberry with different concentrations of Zinc (Zn) and Iron (Fe) found as the best option for higher productivity whereas the treatment T3 with concentration of Zn (0.6% )+ Fe (0.6%) showed the best result in terms of plant height at 30 days to transplanting (8.1 cm), 60 days to transplanting (15.4 cm) and 90 days to transplanting (22.1 cm), Number of leaves plant-1 at 30 days to transplanting (7.3), 60 days to transplanting (21.3) and 90 days to transplanting (27.4), Plant Spread (27.2 cm), runner plant-1 (5.9), yield/ha (6.0 t), fruit length (4.3 cm), fruit weight (29.3 g), fruit diameter (3.4 cm), TSS (9.3o Brix), showed the best results in terms of vegetative growth, yield, quality. Hence the T3 Zn (0.6%) + Fe (0.6%) is best suited for the farmers in terms of growth, yield, quality and net returns.
Neurocognitive Outcomes at Age 2 Years After Neonatal Hypoglycemia in a Cohort of Participants From the hPOD Randomized Trial
Authors: Edwards Taygen , Alsweiler Jane M. , Gamble Greg D. , Griffith Rebecca , Lin Luling , McKinlay Christopher J. D. , Rogers Jenny A. , Thompson Benjamin , Wouldes Trecia A. , Harding Jane E. 
Published: October 2022

ImportanceNeonatal hypoglycemia is common, but its association with later neurodevelopment is uncertain.ObjectiveTo examine associations between neonatal hypoglycemia and neurocognitive outcomes at corrected age 2 years.Design, Setting, and ParticipantsExploratory cohort analysis of the Hypoglycaemia Prevention With Oral Dextrose (hPOD) randomized clinical trial was conducted. The trial recruited participants from January 9, 2015, to May 5, 2019, with follow-up between January 26, 2017, and July 31, 2021. Infants were recruited from 9 maternity hospitals in New Zealand and assessed at home or in a research clinic. Children born late preterm and at term at risk of neonatal hypoglycemia but without evidence of acute or imminent illness in the first hour after birth were screened and treated to maintain blood glucose concentrations greater than or equal to 47 mg/dL.ExposuresHypoglycemia was defined as any blood glucose concentration less than 47 mg/dL, recurrent as 3 or more episodes, and severe as less than 36 mg/dL.Main Outcomes and MeasuresNeurologic examination and tests of development (Bayley III) and executive function. The primary outcome was neurosensory impairment (any of the following: blindness, deafness, cerebral palsy, developmental delay, or executive function total score worse than 1.5 SD below the mean).ResultsA total of 1197 of 1321 (91%) eligible children were assessed at a mean of corrected age 24 months; 616 (52%) were male. Compared with the normoglycemia group, children who experienced hypoglycemia were more likely to have neurosensory impairment (111 [23%] vs 125 [18%]; adjusted risk ratio [aRR], 1.28; 95% CI, 1.01-1.60), particularly if they experienced severe episodes (30 [28%] vs 125 [18%]; aRR, 1.68; 95% CI, 1.20-2.36), but not recurrent episodes (12 [19%] vs 125 [18%]; aRR, 1.06; 95% CI, 0.63-1.80). The risk of cognitive, language, or motor delay was similar between groups, but children who experienced hypoglycemia had lower Bayley-III composite cognitive (adjusted mean difference [aMD], −1.48; 95% CI, −2.79 to −0.18) and motor scores (aMD, −2.05; 95% CI, −3.30 to −0.79).Conclusions and RelevanceIn children born at risk of hypoglycemia but otherwise well, those who experienced neonatal hypoglycemia were more likely to have neurosensory impairment at corrected age 2 years, with higher risks after severe episodes. Further research is required to determine causality.
Mitochondrial network expansion and dynamic redistribution during islet morphogenesis in zebrafish larvae
Authors: Freudenblum Julia , Meyer Dirk , Kimmel Robin A. 
Published: October 2022

Mitochondria, organelles critical for energy production, modify their shape and location in response to developmental state and metabolic demands. Mitochondria are altered in diabetes, but the mechanistic basis is poorly defined, due to difficulties in assessing mitochondria within an intact organism. Here, we use in vivo imaging in transparent zebrafish larvae to demonstrate filamentous, interconnected mitochondrial networks within islet cells. Mitochondrial movements highly resemble what has been reported for human islet cells in vitro, showing conservation in behaviour across species and cellular context. During islet development, mitochondrial content increases with emergence of cell motility, and mitochondria disperse within fine protrusions. Overall, this work presents quantitative analysis of mitochondria within their native environment and provides insights into mitochondrial behaviour during organogenesis.
Off‐Stoichiometry Quaternary Heusler‐Like Semiconductors with Magnetism and Disorder
Authors: Ruan Yurong , Zhong Ke , Zhang Ying , Zhang Fang , Zhang Yubo , Zhang Wenqing 
Published: October 2022

AbstractThe theoretical finding of a large group of intrinsic off‐stoichiometry quaternary Heusler‐like semiconductors with mixing and tunable occupation of 4c‐4d atomic sites, such as FexCoyTiSb with non‐integer x + y > 1 are reported. Those semiconductors are never reported before, and they radically break the well‐recognized 18‐ (or 24‐) valence electron counting (VEC) rule and the exact 4c‐ (or both 4c‐ and 4d‐) atomic sites stoichiometry for the traditional quaternary half‐Heusler (or full‐Heusler) semiconductors. Physically, the novel semiconductors can be designed by following a d‐orbital‐determined compensation rule. The extra atoms fill in the tetrahedral vacancies of the half‐Heusler structure, introduce symmetry‐constrained d orbitals near the Fermi level, large crystal field splitting, and then form a bandgap at appropriate fractional compositions, which leads to an exact compensated electronic structure. The newly established compensation rule reveals an abundant phase space of the quaternary Heusler‐like (2x + 3y = 3 for VECY+Z = 9, 2x + 3y = 4 for VECY+Z = 8, and 2x + 3y = 5 for VECY+Z = 7) compounds. High‐throughput screenings reveal many new FexCoyYZ semiconductors, all of which possess strong disorder, weak magnetism, spin compensation, and wide composition‐range tunability. The intertwined orders may either find functionalities surpassing the existing materials or give rise to new potential applications.
Mapping of Spatiotemporal Auricular Electrophysiological Signals Reveals Human Biometric Clusters
Authors: Huang Qingyun , Wu Cong , Hou Senlin , Yao Kuanming , Sun Hui , Wang Yufan , Chen Yikai , Law Junhui , Yang Mingxiao , Chan Ho‐yin , Roy Vellaisamy A. L. , Zhao Yuliang , Wang Dong , Song Enming , Yu Xinge , Lao Lixing , Sun Yu , Li Wen Jung 
Published: October 2022

AbstractUnderneath the ear skin there are rich vascular network and sensory nerve branches. Hence, the 3D mapping of auricular electrophysiological signals can provide new biomedical perspectives. However, it is still extremely challenging for current sensing techniques to cover the entire ultra‐curved auricle. Here, a 3D graphene‐based ear‐conformable sensing device with embedded and distributed 3D electrodes for full‐auricle physiological monitoring is reported. As a proof‐of‐concept, spatiotemporal auricular electrical skin resistance (AESR) mapping is demonstrated for the first time, and human subject‐specific AESR distributions are observed. From the data of more than 30 ears (both right and left ears), the auricular region‐specific AESR changes after cycling exercise are observed in 98% of the tests and are clustered into four groups via machine learning‐based data analyses. Correlations of AESR with heart rate and blood pressure are also studied. This 3D electronic platform and AESR‐based biometrical findings show promising biomedical applications.
Decoupled Solar Energy Storage and Dark Photocatalysis in a 3D Metal–Organic Framework
Authors: Stanley Philip M. , Sixt Florian , Warnan Julien 
Published: October 2022

AbstractMaterials enabling solar energy conversion and long‐term storage for readily available electrical and chemical energy are key for off‐grid energy distribution. Herein, the specific confinement of a rhenium coordination complex in a metal–organic framework (MOF) unlocks a unique electron accumulating property under visible‐light irradiation. About 15 C gMOF−1 of electric charges can be concentrated and stored for over four weeks without loss. Decoupled, on‐demand discharge for electrochemical reactions and H2 evolution catalysis is shown and light‐driven recharging can be conducted for >10 cycles with ≈90% of the initial charging capacity retained. Experimental investigations and theoretical calculations link electron trapping to MOF‐induced geometry constraints as well as the coordination environment of the Re‐center, highlighting the key role of MOF confinement on molecular guests. This study serves as the seminal report on 3D porous colloids achieving photoaccumulation of long‐lived electrons, unlocking dark photocatalysis, and a path toward solar capacitor and solar battery systems.
A Rapid Effervescent Route to Rational Activation of Cu/g‐C3N4 and bulk MoS2 Cocatalyst for Highly Efficient and Robust Photo‐Fenton Process
Authors: Li Wenxin , Ding Chenjie , Kang Shifei , Gao Weikang , Yang Yang , Cui Lifeng 
Published: October 2022

AbstractHeterogeneous Fenton‐like process with a wide pH range is a promising alternative to traditional homogeneous Fenton reactions. Recently, the boosting effect of MoS2 cocatalysts is widely recognized in Fenton reactions, and the primary mechanism is the promotion of the reduction and recycling of high‐valence metal ions. Unfortunately, integrating heterogeneous Fenton‐like catalysts and MoS2 cocatalyst to form an efficient system remains challenging due to the severe deactivation of MoS2 and the inability of simple physical mixing to speed up the reaction. For the first time, the direct activation of commercially available bulk MoS2 powder in a durable acidic microenvironment is achieved. The foam‐modified photo‐Fenton catalyst (Cu‐CN‐ef) promotes the rapid activation and formed an ideal MoS2‐excited photo‐Fenton system. The significant synergistic effect of the system is ascribed to the outstanding sustainability of Cu‐Mo redox cycling and favorable local acidic microenvironment on the surface of Cu‐CN‐ef. This system works well in outdoor cases with a tiny amount of commercially available Cu‐CN/MoS2 powder, promising a new route for portable and rapid solar‐powered wastewater treatment. The unique effervescence modification method shows great potential in the rational reconstruction of the affinity interface of composite catalysts and efficient solar energy utilization systems.
Whole‐Device Mass‐Producible Perovskite Photodetector Based on Laser‐Induced Graphene Electrodes
Authors: Qu Menglong , Tian Yingxin , Cheng Yi‐Bing , Zhong Jie , Zhang Cheng 
Published: October 2022

AbstractPerovskites have attracted enormous attention in optoelectronics, owing to their excellent optoelectronic properties, low‐cost constituents, and simple solution fabrication approaches. Despite significant advances in large‐scale production of perovskite films, electrode layers—indispensable components of an optoelectronic device—are typically fabricated by depositing noble metals onto perovskite films using complicated techniques, which hinder the large‐scale production of optoelectronic devices. Herein, a whole‐device mass‐producible perovskite photodetector is developed using low‐cost and high‐scalability direct laser writing (DLW) of laser‐induced graphene on a flexible polyimide (PI) film as electrodes, followed by depositing a formamidinium cesium lead triiodide perovskite film using solution methods as the sensing element. The fabricated device exhibits a broad bandwidth (from 365 to 940 nm), a decent responsivity (15.1 mA W−1) and detectivity (5.12 × 1013 Jones), a large photo‐to‐dark current ratio (47.2), and short response time (rise time = 0.4 s and decay time = 0.4 s). The device demonstrates a high humidity (relative humidity = 85%) stability, a long‐term (>48 days) stability, and a high flexibility (0°/90° bending cycles > 1000 times) after encapsulation. The developed whole‐device scalable fabrication sheds light on the mass production and commercialization of perovskite based optoelectronic devices and flexible electronics.
Age at menarche, environmental stress, and social inequality: Evidence from Poland in the 1930s–1950s
Authors: Liczbińska Grażyna , Brabec Marek , Piontek Janusz , Malina Robert M. 
Published: October 2022

AbstractObjectiveTo address the relationship between socioeconomic factors and age of menarche among Polish women born and reared in periods that varied considerably in environmental stresses: the Great Depression of the 1930s, the interval of World War II, and the interval of communist rule following World War II through the 1950s.MethodsThe data set included information on age at menarche and socioeconomic status (SES) of 718 women born during the Great Depression (n = 182), WWII (n = 189), and post‐WWII through the 1950s (n = 347). A structured semi‐parametric statistical model (generalized additive model [GAM] class) was used for analysis. An ANOVA‐like linear model was used to test for marginal effects of SES‐related factors and their interactions together with nonparametric seasonal effect.ResultsThe influence of period of birth, month of birth, region of early childhood, and father's education, and the interaction between period of birth and father's education on age at menarche were statistically significant. During the economic crisis and the interval of WWII, differences in ages at menarche between the extreme categories of father's education were marked. The differences in ages at menarche between women from the lowest and highest social groups were markedly reduced among women born during the post‐war interval. In addition, women born in February–March attained menarche earlier than women born in September–October.ConclusionsUnpredictable conditions associated with the economic crisis and war conditions had a stronger impact on age at menarche among women from families of lower SES compared to women from better economic circumstances. Individuals born and reared in low SES conditions likely suffered more severe deterioration across the spectrum of the standard of living and quality of life compared to those with a higher SES.
Biologische Effekte von auf schwarzem Phosphor basierenden Nanomaterialien auf Zellen und Tiere
Authors: Zhang Xuejiao , Donskyi Ievgen S. , Tang Weihao , Deng Shuo , Liu Daxu , Zhang Siyu , Zhao Qing , Xing Baoshan 
Published: October 2022

AbstractDie bedeutenden Fortschritte bei der Anwendung von auf schwarzem Phosphor basierenden Nanomaterialien (SPNMs) sind auf deren hervorragende Eigenschaften zurückzuführen. Aufgrund der vielfältigen Anwendungsmöglichkeiten dieser Materialien sind die Freisetzung in die Umwelt und eine anschließende Exposition des Menschen praktisch unvermeidlich. Daher muss untersucht werden, wie sich SPNMs auf biologische Systeme und die menschliche Gesundheit auswirken. In dieser umfassenden Übersicht werden die neuesten Erkenntnisse in Bezug auf Wirkungsweise, Mechanismen und Regulierungsfaktoren der endogenen Toxizität von SPNMs in Säugetieren vorgestellt. Diese Ergebnisse bilden die Grundlage für das Verständnis der biologischen Auswirkungen und haben das Ziel, Regulierungsprinzipien zur Minimierung gesundheitsschädlicher Auswirkungen festzulegen.
Electroretinography in adults with high‐functioning autism spectrum disorder
Authors: Friedel Evelyn B. N. , Schäfer Mirjam , Endres Dominique , Maier Simon , Runge Kimon , Bach Michael , Heinrich Sven P. , Ebert Dieter , Domschke Katharina , Tebartz van Elst Ludger , Nickel Kathrin 
Published: October 2022

AbstractThe electroretinogram (ERG) allows the investigation of retinal signaling pathways and has increasingly been applied in individuals with mental disorders in search for potential biomarkers of neurodevelopmental disorders. Preceding ERG examinations in individuals with autism spectrum disorders (ASD) showed inconsistent results, which might be due to the small number of participants, heterogeneity of the ASD population, differences in age ranges, and stimulation methods. The aim of this study was to investigate functional retinal responses in adults with ASD by means of the light‐adapted (photopic) ERG. Light‐adapted ERG measurements were obtained with the RETeval® system applying three different stimulation protocols. In the final analysis, the ERG parameters a‐wave, b‐wave, the photopic negative response (PhNR), the photopic hill parameters as well as additional amplitude ratios were compared between 32 adults with high‐functioning ASD and 31 non‐autistic controls. Both groups were matched with regard to sex and age. No significant functional retinal differences in amplitude or peak time of the a‐ or b‐wave, PhNR, the photopic hill parameters or the ERG‐amplitude ratios could be detected in individuals with ASD compared to non‐autistic participants. The absence of electrophysiological functional retinal alterations in ASD, suggests that changes in visual perception, such as increased attention to detail or visual hypersensitivity in ASD, are not due to impairments at early levels of retinal signal processing.
Innervation of the human vulvar vestibule: A comprehensive review
Authors: Velikonja Leah , Giovannetti Olivia , Adams Michael A. , Tomalty Diane 
Published: October 2022

AbstractPain of the vulvar vestibule, including provoked vestibulodynia, is prevalent among women, yet challenging to treat due to its multifactorial etiology. Recent evidence indicates a neuroproliferative subtype in which hypersensitivity of the vulvar vestibule is due, in part, to hyperinnervation. Detailed knowledge regarding the innervation of the vulvar vestibule is crucial to understanding and treating pain conditions impacting this region. The purpose of this review is to consolidate the current evidence regarding the innervation of the human vulvar vestibule and discuss the implications of this innervation for pathological conditions affecting this tissue. A comprehensive review of the literature was conducted using keywords including vulvar vestibule, innervation, and vestibulodynia to identify articles concerning the innervation of the vulvar vestibule. Fifteen studies published between 1998 and 2017 were reviewed. Evidence from immunohistochemical investigations support that the vulvar vestibule has nociceptive, mechanosensory, sympathetic, and parasympathetic innervation. In pathological samples, hyperinnervation supports the neuroproliferative etiology of provoked vestibulodynia. Additionally, there is some evidence supporting the role of the pudendal nerve in vulvar vestibule innervation, although no cadaveric studies have been reported to date. Progress has been made in our understanding of the innervation of the vulvar vestibule, though further research into the origin of sensory and autonomic innervation of this region is needed. Advancing the knowledge of vulvar vestibule innervation is crucial towards improving our understanding of the function of this tissue, in addition to informing the etiology and management of pain syndromes impacting this region.
A longitudinal analysis of person‐centred therapy with suicidal clients
Authors: Sohal Amrita , Murphy David 
Published: October 2022

AbstractBackgroundThere have been substantial research efforts demonstrating the effectiveness of person‐centred therapy. However, little research has investigated whether person‐centred therapy is effective in facilitating psychological growth amongst clients experiencing suicidal ideation and serious mental health difficulties.AimThis study aimed to determine whether suicidal clients who received person‐centred therapy experienced increased levels of authenticity, well‐being and psychological distress. The predictive validity of authenticity and well‐being upon psychological distress was also tested.MethodThe study utilised quantitative, longitudinal methodology. Data were collected from a clinical sample of clients receiving person‐centred therapy at a counselling research clinic (N = 56) over the course of 20 sessions.ResultsThere were statistically significant improvements in levels of authenticity, well‐being and psychological distress over 20 sessions of therapy; a minimum of 15 sessions were required for significant change to be observed. Authenticity and well‐being were negatively associated with psychological distress, whilst authenticity and well‐being were positively associated with each other. Early authenticity and well‐being predict levels of distress later in therapy. These results provide initial evidence to support Rogers' theory of therapy, which is suitable for clients experiencing both mild and severe distress; the findings refute the view that person‐centred therapy is only suitable for the “worried well.”ImplicationsThere is now preliminary justification for person‐centred therapy being suitable for suicidal clients. Person‐centred therapists could consider offering suicidal clients at least 15 sessions to achieve meaningful change; ethical considerations pertaining to this are explored.
Virtual testing of a new conjecture for the stone ascending device in Egyptian pyramids by means of a multibody dynamics simulation
Authors: Sarbia Franco , Cirelli Marco , Giannini Oliviero , Cera Mattia , Valentini Pier Paolo , Pennestrì Ettore 
Published: October 2022

AbstractThe ascending of rock blocks for building the Egyptian pyramids has been the topic of many discussions among Egyptologists. One of the authors (F.S.) conjectured a method that could be used for the task. In his own words: “This is the story of the random discovery of an oscillating machine, capable of using gravity to ascend, as the sail goes upwind.” In this article, by means of a virtual prototype and multibody dynamics simulation, the physical feasibility of such method is tested for the first time. From historical and archeological bases, this investigation presents the fundamental functional features of the virtual model components for the ascending of the stones. Furthermore, the methodological details for the model setup, as well as the discussion on the stone ascending movements, are herein addressed. The main results obtained from the simulation include the evaluation of the advancement‐per‐cycle of the conjectured ascending device and the corresponding required driving forces.
Engineering Human Neuroglobin into a Cytochrome c‐Like Protein with a Single Thioether Bond in Non‐native State
Authors: Chen Lei , Yuan Hong , Wang Xiao‐Juan , Li Lianzhi , Tan Xiangshi , Lin Ying‐Wu 
Published: October 2022

AbstractA double mutant of human H64M/V71C neuroglobin (Ngb) was engineered, which formed a single thioether bond as that in atypical cytochrome c, whereas the heme distal Met64 was oxidized to both sulfoxide (SO‐Met) and sulfone (SO2‐Met). By contrast, no Cys‐heme cross‐link was formed in V71C Ngb with His64/His96 coordination, as shown by the X‐ray crystal structure, which indicates that an open distal site facilitates the activation of heme iron for structural modifications.