bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of sowing dates and seeding rates on the yield of winter wheat in the conditions of the steppe zone of chernozem soils of the Volgograd region
Authors: Guzenko A. Y. , Sopunkov V. L. 
Published: December 2022

Relevance and methodology. In the conditions of the arid steppe zone of the Volgograd region in the Elansky district in 2018–2021, we studied the effect of sowing dates and seeding rates of seeds of winter wheat Zernogradka 11 on productivity. Sowing dates and seeding rates are considered by various sources as two main factors in increasing grain yields without any additional economic costs. The predecessor was black bare . The technology of cultivation of the variety Zernogradka 11 in field experiments was according to B.A. Dospekhov and the method of state variety testing of agricultural crops. The experiments were carried out for 5 sowing dates (III decade of August; I, II, III decades of September and I decade of October) and seding rates period (4, 5 and 6 million pcs/ha). Seedlings, at different sowing dates, appeared at different intervals, which is associated with a changing temperature regime.Result. Based on the data obtained over the years of research it can be concluded that there is a decrease in productive stalk with advancement to later sowing dates. The highest yield was obtainedthen sowing in I decade of September. For other dates and seeding rates, except for the III decade of August, there was a noticeable decrease in indicators of the yield structure. The optimal seeding rate was found to be 5 and 6 million pcs/m2. Statistical processing of the obtained data was carried out and the dependence of the yield of winter wheat on sowing dates and seeding rates on average for 2018 — 2021 was revealed. It was found that the model describes the phenomenon well in almost all indicators, but the model of relationship between individual factors and the yield oneeds to be improved. The study showed that the influence of sowing dates and seeding rates are not sufficiently interconnected.
Ecological plasticity of winter wheat yield when cultivating on different predecessors in arid conditions of Eastern Caucasus
Authors: Morozov N. A. , Khodzhaeva N. A. , Khripunov A. I. , Obshchiya E. N. 
Published: December 2022

Relevance. The selection of the best winter wheat precursors that provide low yield variability in contrasting years is an important task of farming.Methods. Studies were carried out in 2017–2021 at the Prikumskaya Experimental Breeding Station in a 6-field crop rotation, where winter wheat was placed on bare and full fallow and semifallow. The aim of the research was to evaluate the precursors in different nutritional backgrounds from the position of low variability of yield, ecological stability and high adaptability to the conditions of the arid zone of the Stavropol Territory.Results. The hydro-thermal coefficient of summer-autumn period was 0,22 and of spring-summer period — 0,06 units drier than the average summer value. The pre-sowing period was especially unfavorable (HTC = 0.22). The stocks of productive moisture in a meter layer of soil in autumn were considerably below the norm on bare fallow in 40% of years of experiment and on other predecessors — in 80% of years. Yield of winter wheat varied from 2.43 to 4.46 t/ha on bare fallow on control, 2.86 to 4.93 t/ha — on fertilized variant, 1.98 to 4.72 and 2.15 to 5.35 t/ha— on ful fallow, 0.59 to 2.19 and 0.64 to 2.44 t/ha — on semifallow. And the environmental conditions index ranged from –0.51 to +1.52 and –0.64 to+1.43; from –0.90 to+1.84 and –1.10 to +2.10; from –0.72 to + 0.88 and –1.19 to +0.79 respectively. Maximum yields in all nutritional backgrounds were obtained on bare and full fallow. Only 1 year out of 5 was favorable as it had positive environmental conditions index values. The environmental plasticity ranged from 1.67 to 3.04. The highest yield variability (47.1%) and maximum stress tolerance (–1.6 –1.98 t/ha) was observed for the half fallow Semifallow. Bare fallow was the most flexible under stress conditions of cultivation as it had the highest yield (2.94–3.50 t/ha) and the lowest variability (26.4%) compared to other precursors.
Biologically active substances in raspberry varieties of Kazakhstan selection
Authors: Shingisov A. U. , Alibekov R. S. , Tastemirova U. U. 
Published: December 2022

Relevance. The most well-known biologically active substances are natural antioxidants, which consist of: polyphenols, flavonoids, various aromatic hydroxy acids, anthocyanins, vitamins C and E, carotenoids and other compounds. Raspberries are rich in phenolic phytochemicals, especially flavonoids, such as anthocyanin pigments, which give raspberries a dark red color. The aim of the study is to analyze biologically active substances of raspberries of Kazakhstan breeding in laboratory conditions. Research objectives: theoretical analysis, collection and structuring of laboratory data on biologically active substances, appropriate conclusion.Methods. The physicochemical properties and chemical indicators in the various raspberry varieties of the Kazakhstan selection were studied, such as: Anar, Arai and Salem. Mostly the recognized and available research methods were used. The method of determining the amount of soluble solids is based on using a refractometer. The found value is expressed in units of the mass fraction of sucrose in an aqueous solution of sucrose, which under given conditions has the same refractive index as the analyzed solution, in % (Brix) (GOST 51433: 1999).Results. Physico-chemical parameters were studied: the dry matter content, total sugars and titrated acidity. It is established that among the raspberry varieties considered, Anar variety has the highest values. Anar also has the highest chemical indicators: the sugar acid index, the content of ascorbic acid (vitamin C), the total content of phenols and the total content of flavonoids. The total content of phenols and flavonoids in the varieties Anar (860 µg/ml and 188 µg/ml, respectively), Arai (870 µg/ml and 189 µg/ml, respectively) and Salem (855 µg/ml and 187 µg/ml, respectively) have similar values. Extracts of these raspberries sorts could be advised for the enrichment of the nutritional value composition of food products.
Assessment of the bioavailability of flavonoids in herbal beverages with antioxidant properties
Authors: Fatkullin R. I. , Kalinina I. V. , Naumenko N. V. , Popova N. V. , Naumenko E. E. , Ivanisova E. , Tokár M. , Antonova A. D. 
Published: December 2022

Relevance. The development of fermented herbal beverages will make it possible not only to process grain crops as efficiently as possible, but also to meet the needs of people with intolerance to milk components, as well as those who adhere to a vegetarian diet. As one of the directions, it is possible to offer production of fermented vegetable drinks with predetermined properties by enriching them with antioxidants of polyphenolic nature. These technologies will minimise the risks of non-communicable diseases in the Russian Federation and stabilise public health in the long term.Methods. Six samples of fermented herbal beverages were identified as objects of study, two of which were obtained by fermentation of wheat and barley grains using "Bifivit" starter, powdered flavonoid taxifolin was added to other two samples at the fermentation stage, while the last two used the hydroxypropyl-betacyclodextrin encapsulated form of taxifolin. Total flavonoid content using spectrophotometric method, antioxidant activity(AOA) using DPPH-method as well as bioavailability index and digestibility criterion were determined in all tested samples.Results. All the samples of fermented herbal beverages with taxifolin are characterized by sufficiently high flavonoid content. The samples containing encapsulated forms of the flavonoid have, on average, 7 to 8% lower values than the samples of herbal drinks containing the native form of the flavonoid. At the same time, the bioavailability index for the samples containing encapsulated forms of flavonoid was on average 40 to 42% higher, indicating the effectiveness of the encapsulation process. The highest values of antioxidant activity were characteristic of the plant drinks enriched with the initial form of taxifolin, which is probably due to the creation of a protective shell and a decrease in the AOA values by 10–12% on average in samples with encapsulated form. The process of fermentation of vegetable raw materials leads to an increase in their digestibility, as evidenced by the growth of the infusoria Tetrahymena pyriformis. Introduction of taxifolin into the formulation of drinks both in its original and encapsulated form increases the growth of protozoa by 187±4–315±3%.
Economic and social importance of residency for improving the quality of experts in the field of veterinary medicine
Authors: Akchurin S. V. , Yuldashbaev Yu. A. , Dyulger G. P. , Akchurina I. V. , Obukhova M. E. , Latynina E. S. , Khrenova Ya. M. 
Published: December 2022

Relevance: In Russia, the issue of conducting an experiment on the implementation of educational programs of residency in veterinary medicine is being discussed. The purpose of the study is to determine the potential relevance of the residency program "Veterinary Medicine" among students of specialty 36.05.01 Veterinary Medicine.Methods. The survey method was used to conduct the study. The questionnaire was posted on the "Google forms" platform. The link to the questionnaire was distributed among students of the 1–5th year of the specialty 36.05.01 Veterinary Medicine through ads on social networks.Results. It was revealed that 40,7% of students of specialty Veterinary Medicine are considering admission to residency. The leading motives for continuing training in residency are: obtaining deeper knowledge and professional skills in the field of interest and increasing competitiveness in the labor market (to take a position of interest, etc.). According to respondents, the veterinary residency program should have a number of characteristics: free tuition; program of interest to students; mixed attendance mode; it is desirable that training would take place in the same city in which the training for specialist›s degree took place. The main reasons why students do not want to continue their studies in residency are: not seeing meaning in formal education at a university if there is an opportunity to study under flexible internship programs and special courses; the desire to try their hand at work; the need to earn a living.
Aspects of the formation of post-vaccination immunity against porcine circovirus infection and its correction
Authors: Burkov P. V. , Scherbakov P. N. , Derkho M. A. , Rebezov M. B. 
Published: December 2022

Relevance. Prevention of circovirus diseases in swine management is one of the urgent problems in the industry. The article provides data on the results of the use of two regimens for administering vaccines against circovirus infection to piglets according to immunological, biochemical and zootechnical indicators.Methods. The work was carried out on piglets, which were vaccinated with "Ingelvak CircoFLEX" vaccine (Germany) against circovirus at the age of 21 days, in the experimental group it was administered together with "leukocytic lysate" obtained from donors hyperimmunized with this vaccine. Evaluation of the effectiveness of post-vaccination immunity formation was carried out based on the results of immunological, biochemical, zootechnical and statistical studies.Results. It was established that when the vaccination was combined with the introduction of «leukocytic lysate» from hyperimmunized donors, the number of piglets with a positive test for the presence of viral neutralizing antibodies was 79.30–82.33%, in the control — 67.80–71.60%, as a result of changes in the leukocytic blood pool within the normal limits. In piglets of experimental group blood concentration of total protein and albumins starting from 60-day age exceeds control level by 7.73–8.68 and 17.84–30.27% respectively. In the experimental group, compared with the control group, the co-storage of animals is increased by 9.02%, the live weight of piglets at the end of the nursery period is increased by 12.88 kg, or 31.85%, based on one head and the value of medium increases in live weight — by 90 g, or 26.01%.
Risiko Keamanan Data Pribadi Pelanggan Dalam Penggunaan Big Data
Authors: Prayoga Dimas , Hayati Fisilmy , Putra Hanif Athar Yuana , Rizki Irfan Nur , Fitroh Fitroh 
Published: December 2022

Abstrak— Seiring zaman yang terus berkembang, teknologi pun semakin canggih. Dewasa ini, teknologi telah menjadi kebutuhan sekaligus menjadi ‘teman hidup’ manusia. Berbagai macam teknologi yang ada mulai dari teknologi di bidang telekomunikasi, transportasi, kesehatan, bahkan dalam bidang pertahanan dan keamanan sangat membantu bagi manusia dalam menjalankan aktivitas nya sehari-hari. Dimana dalam penerapannya teknologi ini memerlukan data pengguna yang akan dijadikan sebagai bahan dalam pertimbangan mengenai kegunaan dari teknologi tersebut. Data-data ini dapat dikumpulkan dan diolah dengan menggunakan suatu teknologi yang dinamakan Big Data. Diantara data-data yang dikumpulkan, ada data yang sensitif. Data yang sensitif yaitu data pribadi yang rentan untuk dicuri, dirusak, dan dimanipulasi. Pada paper ini akan dibahas mengenai solusi untuk mencegah risiko yang ditimbulkan oleh penggunaan Big data terhadap data pribadi, mulai dari melakukan pengamanan kode komputasi, menerapkan validasi dan penyaringan input yang menyeluruh, menerapkan access control granular, mengamankan penyimpanan dan perhitugan data, serta meninjau dan menerapkan privasi, pemeliharaan data mining, dan analisis.Kata kunci: Big Data, keamanan, data pribadi, data pengguna
The Effect of Leaflet as Educational Media on the Pre-Conception Nutrition for Prospective Bride and Groom
Authors: Husna Arfah , Marniati Marniati , Silvia Putri Enda , Maisyaroh Fitri Siregar Siti , Arafah Carolina Siti 
Published: December 2022

Nutritional status of the prospective bride or pre-wedding woman for three or six months during the preconception period will determine the condition of the baby being born. Pre-conception perfect nutrition is the key to the birth of a normal and healthy baby as one of the specific nutrition intervention efforts is the prevention of stunting cases.. This study aims to examine the effect of the intervention of leaflet media education methods on increasing knowledge about preconceptional nutrition of the bride and groom. Methods: This study uses a Quasi-Experimental design with one group before and after intervention design on 20 prospective brides at KUA, Johan Pahlawan District, West Aceh Regency. Result: Based on the results of the bivariate test, it is known that there is a significant effect of the leaflet media education method on increasing knowledge about preconception nutrition of the bride and groom. To conclude, the intervention of the leaflet media education method has an effect on increasing knowledge, about preconception nutrition of the bride and groom. Keywords: Prospective Bride and Groom, Preconception Nutrition, Knowledge, Leaflet
Strategi manajemen produksi untuk memaksimalkan profitabilitas pada provider perspektif islam
Authors: Syukur Musthafa , Fitri Yoviana 
Published: December 2022

Penelitian ini bertujuan untuk mengungkap strategi manajemen produksi dalam menghasilkn profitabilitas pada persuasahaan provider sehingga dapat mengahsilkan kemaksimlakan dalam laba perusahaan. Metode yang di gunakan adalah kualitatif dengan pendekatan studi literatur. Hasil dari penelitian ini dikemukan bahwa starategi yang dilakukan oleh provider dengan mengatasnamakan embel embel islam terbukti efektif untuk menarik custumer dalam membeli yang di tawarkan oleh provider, sehingga provider menghasilkan laba profit yang melebiha standart yang ditentukan oleh perusahaan.
AUF-1 knockdown in mice undermines gut microbial butyrate-driven hypocholesterolemia through AUF-1–Dicer-1–mir-122 hierarchy
Authors: Das Oishika , Kundu Jayanta , Ghosh Atanu , Gautam Anupam , Ghosh Souradeepa , Chakraborty Mainak , Masid Aaheli , Gauri Samiran Sona , Mitra Debmalya , Dutta Moumita , Mukherjee Budhaditya , Sinha Surajit , Bhaumik Moumita 
Published: December 2022

Introduction and objectiveCholesterol homeostasis is a culmination of cellular synthesis, efflux, and catabolism to important physiological entities where short chain fatty acid, butyrate embodied as a key player. This discourse probes the mechanistic molecular details of butyrate action in maintaining host-cholesterol balance.MethodsHepatic mir-122 being the most indispensable regulator of cholesterol metabolic enzymes, we studied upstream players of mir-122 biogenesis in the presence and absence of butyrate in Huh7 cells and mice model. We synthesized unique self-transfecting GMO (guanidinium-morpholino-oligo) linked PMO (Phosphorodiamidate-Morpholino Oligo)-based antisense cell-penetrating reagent to selectively knock down the key player in butyrate mediated cholesterol regulation.ResultsWe showed that butyrate treatment caused upregulation of RNA-binding protein, AUF1 resulting in RNase-III nuclease, Dicer1 instability, and significant diminution of mir-122. We proved the importance of AUF1 and sequential downstream players in AUF1-knock-down mice. Injection of GMO-PMO of AUF1 in mouse caused near absence of AUF1 coupled with increased Dicer1 and mir-122, and reduced serum cholesterol regardless of butyrate treatment indicating that butyrate acts through AUF1.ConclusionThe roster of intracellular players was as follows: AUF1-Dicer1-mir-122 for triggering butyrate driven hypocholesterolemia. To our knowledge this is the first report linking AUF-1 with cholesterol biogenesis.
The clinical application of metagenomic next-generation sequencing in infectious diseases at a tertiary hospital in China
Authors: Wang Chuwen , Yan Danying , Huang Jiajia , Yang Naibin , Shi Jiejun , Pan Shou , Lin Gaoqiang , Liu Ying , Zhang Yingying , Bian Xueyan , Song Qifa , Qian Guoqing 
Published: December 2022

BackgroundCompared with traditional diagnostic methods (TDMs), rapid diagnostic methods for infectious diseases (IDs) are urgently needed. Metagenomic next-generation sequencing (mNGS) has emerged as a promising diagnostic technology for clinical infections.MethodsThis retrospective observational study was performed at a tertiary hospital in China between May 2019 and August 2022. The chi-square test was used to compare the sensitivity and specificity of mNGS and TDMs. We also performed a subgroup analysis of the different pathogens and samples.ResultsA total of 435 patients with clinical suspicion of infection were enrolled and 372 (85.5%) patients were finally categorized as the ID group. The overall sensitivity of mNGS was significantly higher than that of the TDMs (59.7% vs. 30.1%, P &lt; 0.05). However, there was no significant difference in the overall specificity between the two methods (83.3% vs. 89.6%, P = 0.37). In patients with identified pathogens, the positive rates of mNGS for detecting bacteria (88.7%), fungi (87.9%), viruses (96.9%), and Nontuberculous mycobacteria (NTM; 100%) were significantly higher than those of TDMs (P &lt; 0.05). The positive rate of mNGS for detecting Mycobacterium tuberculosis was not superior to that of TDMs (77.3% vs. 54.5%, P = 0.11). The sensitivity rates of mNGS for pathogen identification in bronchoalveolar lavage fluid, blood, cerebrospinal fluid, pleural fluid, and tissue were 72.6%, 39.3%, 37.5%, 35.0% and 80.0%, respectively.ConclusionWith the potential for screening multiple clinical samples, mNGS has an overall advantage over TDMs. It can effectively identify pathogens, especially those that are difficult to identify using TDMs, such as NTM, chlamydia, and parasites.
Thermal structure and sediment bulk density of the MV420 mud volcano on the continental slope of the Canadian Beaufort Sea and its implications for the plumbing system
Authors: Kim Young-Gyun , Jin Young Keun , Hong Jong Kuk , Paull Charles , Caress David , Jang ChanHee , So Byung-Dal 
Published: December 2022

The shallow migration path of mudflow of the mud volcano MV420 on the continental slope of the Canadian Beaufort Sea is investigated in terms of thermal and geotechnical characteristics. MV420 is a nearly flat topped active mud volcano that emits methane and fluidized mud. Its top is at a depth of water of 420 m, within the gas hydrate stability zone. During the summer 2017 IBRVAraonexpedition, several measurements of marine heat flow were conducted in the area of juvenile mud mound/pond morphologies identified by multibeam bathymetry and backscatter intensity images obtained by the Monterey Bay Aquarium Research Institute’s autonomous underwater vehicle. The heat probe (a gravity corer with temperature, pressure, and tilt sensors) appeared to penetrate to a depth of &gt;70 m below the seafloor. The sediment bulk density in the mudflow migration path of MV420, estimated by pressure change with controlled stretches of a winch cable, was 1.56 g/cm3. The subsurface temperature reaches up to 18°C and profiles show that the maximum local temperature occurs from 20 to 40 m below the seafloor, implying substantial vertical variability of geothermal gradients. Our finding of large positive and small negative geothermal gradients above and below the depth of the local temperature maximum may represent stagnant hot mud along the mudflow migration path, indicating a pulsative eruption of the mudflow. Gas hydrate is stable only within a few meter thick layer near the seafloor above the path because of the cold bottom water (0.4°C) covering the top of the mud volcano. Furthermore, the thermal conductivity of 0.939 W/m/K and the marine heat flow of 22.5 mW/m2at a control site outside MV420 is estimated as the background heat flow in the slope, for which little data exists.
Well-controlled gestational diabetes mellitus without pharmacologic therapy decelerates weight gain in infancy
Authors: Li Chao , Cai Yixi , Li Yinying , Peng Bin , Liu Yongfang , Wang Zhenming , Yang Ting , Hu Yirong , Fu Yajun , Shi Tingmei , Peng Hong , Zhang Yue , Chen Jie , Li Tingyu , Chen Li 
Published: December 2022

AimThere are no prospective longitudinal studies on the association between well-controlled gestational diabetes mellitus (GDM) without pharmacologic therapy and the physical growth of offspring in infancy. We aimed to identify the trajectories in physical growth (from 0–12 months of age) in the offspring of mothers with well-controlled GDM without pharmacologic therapy in a prospective cohort in China.MethodsThis study included 236 offspring of mothers with GDM and 369 offspring of mothers without GDM. Mothers with GDM were not on pharmacologic therapy. The length and weight of infants were measured at 0, 1, 3, 6, and 12 months. Linear mixed-effect models and linear mixed-effect models were applied.ResultsThe fully adjusted model showed that the weight-for-age z-score (WAZ), length-for-age z-score (LAZ), and BMI-for-age z-score (BMIZ) were similar at birth for the GDM and control groups. However, subsequent increases in WAZ and BMIZ for the GDM group lagged the increases for the control group at the subsequent periods of observation, 0–1, 0–6, and 0–12 months.ConclusionsWell-controlled GDM without pharmacologic therapy may normalize physical growth of offspring at birth and decelerate their weight gain in infancy. Whether glycemic control can mitigate the long-term effects of GDM on the growth trajectory in offspring remains unclear.