bluuebunny/crossref_metadata_2025_split huggingface dataset:
STRATEGI PEMASARAN DALAM MEMPERTAHANKAN EKSISTENSI BISNIS OLEH-OLEH KHAS LOMBOK DITENGAH PANDEMI COVID 19 ( Studi Kasus Pada Toko Oleh-Oleh Sasak Maiq)
Authors: Septika Baiq Herdina , Krisnahadi Tama , Aryani Menik 
Published: December 2022

Abstract: This study aims to determine the marketing strategy implemented by Sasak Maiq SMEs during the Covid 19 pandemic, especially related to the marketing mix. This study uses a qualitative method, namely a case study that produces descriptive data set out in words. Sources of data in this study using purposive sampling and data collection techniques in this study the authors made a direct visit to UKM Sasak Maiq to conduct personal interviews with the main director, employees and several consumers. The strategy carried out by Sasak Maiq to be able to survive in the midst of the Covid 19 Pandemic is the Bauran 4P (Product, Promotion, Price and Place) mix. Based on the research that has been done, the researcher concludes that there are several strategies used related to the Marketing Mix, namely the product strategy, namely food innovation, the promotion strategy, namely participating in major events related to MSME product exhibitions and sales through social media, the price strategy, namely price discounts, and the marketing strategy. place, namely flexibility in product delivery. Even though there are financial constraints, Sasak Maiq can still find solutions and alternatives, namely by managing finances, namely by product innovation, maximizing social media and maximizing delivery services. Keywords: Marketing Strategy, Marketing MixAbstrak: Penelitian ini bertujuan untuk mengetahui strategi pemasaran yang diterapkan UKM Sasak Maiq selama pandemi Covid 19 khususnya terkait dengan bauran pemasaran (Marketing Mix). Penelitian ini menggunakan metode kualitatif, yaitu studi kasus yang menghasilkan data- data deskriptif yang dituangkan dalam kata-kata. Sumber data pada penelitian ini menggunakan teknik Purposive Sampling dan teknik pengumpulan data pada penelitian ini penulis melakukan kunjungan langsung ke UKM Sasak Maiq untuk melakukan wawancara pribadi dengan Direktur utama, karyawan-karyawan dan beberapa konsumen. Strategi yang dilakukan oleh Sasak Maiq untuk bisa tetap bertahan ditengah Pandemi Covid 19 yaitu Bauran 4P (Product, Promotion, Price and Place). Berdasarkan penelitian yang sudah dilakukan maka peneliti menyimpulkaan ada beberapa strategi yang digunakan terkait dengan Marketing Mix yaitu strategi product yaitu inovasi makanan, strategi promotion yaitu mengikuti event-event besar terkait pameran produk UMKM dan penjualan melalui sosial media, strategi price yaitu potongan harga, dan strategi place yaitu fleksibilitas dalam pengiriman produk. Meskipun ada kendala keuangan tetapi Sasak Maiq masih bisa menemukan solusi dan alternatifnya yaitu dengan mengelola keuangan yaitu dengan inovasi produk, memaksimalkan media sosial dan memaksimalkan layanan antar atau delivery. Kata Kunci : Strategi Pemasaran, Bauran Pemasaran
ANALISIS KINERJA GURU MENGGUNAKAN TEKNOLOGI INFORMASI DALAM PEMBELAJARAN DI SEKOLAH DASAR 44 MATARAM
Authors: Anam M Chairul 
Published: December 2022

Abstrak: Penelitian ini bertujuan untuk mendeskripsikan keterampilan guru menggunakan teknologi informasi dalam pembelajaran di sekolah dasar. Metode penelitian yang digunakan adalah metode penelitian deskriptif kualitatif dengan langkah-langkah pendahuluan, lapangan dan analisis data. Sumber data seluruhnya adalah 8 orang di SDN 44 Mataram, 3 guru laki-laki dan 5 guru perempuan. Teknik pengumpulan data yang digunakan adalah observasi. Lembar analisis dan lembar observasi kinerja guru dijadikan sebagai alat penelitian. Teknik analisis data dilakukan dengan menggunakan teknik analisis data kualitatif. Hasil penelitian menunjukkan bahwa keterampilan guru untuk mengintegrasikan laptop, internet dan Infocus di pendidikan dasar berada pada tingkat menengah. Sebagian besar guru sudah memahami penggunaan teknologi informasi dalam pembelajaran dan dapat merancang presentasi dan menampilkan materi pembelajaran dengan mudah, tetapi mereka juga menggunakan teknologi informasi untuk mengembangkan media pembelajaran dan merancang pembelajaran online.Keterampilan menggunakan fungsi-fungsi masih rendah. Kesimpulan dari penelitian ini adalah keterampilan guru dalam menggunakan teknologi informasi dalam pembelajaran di sekolah dasar berada pada kategori sedang. Mengembangkan media pembelajaran dan meningkatkan keterampilan dalam menggunakan fitur desain pembelajaran online memerlukan bimbingan dan dukungan ahli.Kata kunci: Guru; Keterampilan; Pembelajaran; Sekolah dasar; Teknologi informasi.Abstract: This study aims to describe the skills of teachers using information technology in learning in elementary schools. The research method used is descriptive qualitative research method with preliminary steps, field and data analysis. Sources of data are 8 people at SDN 44 Mataram, 3 male teachers and 5 female teachers. The data collection technique used is observation. The analysis sheet and the teacher's performance observation sheet were used as research tools. The data analysis technique was carried out using qualitative data analysis techniques. The results showed that the teacher's skills in integrating laptops, internet and Infocus in basic education were at the secondary level. Most teachers already understand the use of information technology in learning and can design presentations and display learning materials easily, but they also use information technology to develop learning media and design online learning. Skills in using functions are still low. The conclusion of this study is that the skills of teachers in using information technology in learning in elementary schools are in the medium category. Developing learning media and improving skills in using online learning design features requires expert guidance and support.Keywords: Teachers; Skills; Learning; Elementary school; Information technology.
SOLUSI REALITAS DALAM MENDESAIN PARADIGMA PENDIDIKAN MASA DEPAN
Authors: Ardiansyah Vendra , Nuraini Novi , Panjianum Andi 
Published: December 2022

Abstract : The purpose of this study is to identify and describe the reality solutions in designing the future educational paradigm. The method used in this research is a literature study and is included in qualitative descriptive research. The researcher tries to examine various literatures about reality solutions in designing future educational paradigms that are sourced from various scientific journal articles and other book sources. This study was carried out through stages, starting with a literature search and then organizing the study followed by a Content Analytic analysis in order to understand reality solutions in designing future educational paradigms. The results of this study are in the form of descriptions of solutions in solving problems faced by future educational paradigms in terms of two aspects of education, namely traditional education and modern education. Keywords: Solution, Paradigm, Traditional and Modern EducationAbstrak : Tujuan penelitian ini ialah untuk mengetahui dan mendeskripsikan solusi realitas dalam mendesain paradigm pendidikan masa depan. Metode yang digunakan dalam penelitian ini ialah kajian studi literature dan termasuk kedalam penelitian deskriptif kualitatif. Peneliti berusaha mengkaji dari berbagai literature tentang solusi realitas dalam mendesain paradigma pendidikan masa depan yang bersumber dari berbagai artikel jurnal ilmiah maupun sumber buku lainnya. Kajian ini dilakukan melalui tahapan tahapan yakni dimulai dari pencarian literature lalu pengorganisasian kajian disambung dengan menganalisis secara Content Analytic guna memahami solusi realitas dalam mendesain paradigma pendidikan di masa depan. Hasil penelitian ini berupa uraian dari solusi dalam pemecahan masalah yang dihadapi paradigam pendidikan masa depan yang ditinjau dari dua aspek pendidikan yakni pendidikan tradisional dan pendidikan modern.Kata Kunci: Solusi, Paradigma, Pendidikan Tradisional dan Modern
IMPLEMENTASI SISTEM PENDIDIKAN NON FORMAL SANTRIWATI YANG BERSEKOLAH MADRASAH ALIYAH DI PONDOK PESANTREN ANWARUL HALIMY SESELE LOMBOK BARAT
Authors: Kholisussa`di Kholisussa`di , Fahmi Agus , Purmadi Ary 
Published: December 2022

Abstract: Abstract: Non-formal education is education that can be carried out in stages but is not official and the material is strengthening in formal educational institutions, such as educational units for courses, packages A, B, and C. Islamic non-formal education includes Islamic boarding schools. The focus of the problem is how to implement the non-formal education system for female students. The purpose of the study was to determine the implementation of the non-formal education system "santriwati" who attended Madrasah Aliyah at the Anwarul Halimy Sesele Islamic boarding school, West Lombok. The research method used in this study is a qualitative research method, namely an approach whose research findings are not obtained through statistical procedures or other forms of calculation. The results showed that the Anwarul Halimy Islamic boarding school applied the same learning method as other Islamic boarding schools throughout Indonesia and abroad in general and the materials and books taught or presented were the same as the standards of Islamic boarding schools throughout Indonesia and elsewhere. abroad, because basically the study books discussed have the same reference source. Keywords: Santriwati Non Formal Education System Abstrak: Pendidikan non formal adalah pendidikan yang dapat dilakukan secara berjenjang tapi tidak bersifat resmi dan materinya bersifat penguatan pada lembaga pendidikan formal, Seperti satuan pendidikan kursus-kursus, paket A, B, dan C. Pendidikan non formal Islam diantaranya Pesantren. Fokus masalahnya adalah bagaimana Implementasi sistem pendidikan Non Formal santriwati. tujuan penelitian adalah untuk mengetahui Implementasi sistem pendidikan Non Formal “santriwati” yang bersekolah Madrasah Aliyah di pondok pesantren Anwarul Halimy Sesele Lombok Barat. Metode penelitian yang digunakan pada penelitian ini adalah metode penelitian kualitatif yaitu pendekatan yang temuan-temuan penelitiannya tidak diperoleh melalui prosedur statistik atau bentuk perhitungan lainnya. Hasil penelitian menunjukkan bahwa pondok pesantren Anwarul Halimy menerapkan metode pembelajaran yang sama dengan pembelajaran pondok pesantren lainnya yang ada di seluruh indonesia maupun luar negeri pada umumnya dan materi-materi beserta kitab-kitab yang diajarkan atau disajikan sama dengan standar pondok pesantren di seluruh indonesia maupun di luar negeri, karena pada dasarnya kitab-kitab kajian yang dibahas sumber refrensinya sama. Kata Kunci: Sistem Pendidikan Non Formal Santriwati
‘Informal Infrastructure’ of Prototyping: Practicing Organisation by Performing Materiality
Authors: García Sandra Fernández , Valle Francisco Sánchez 
Published: December 2022

In recent years, sheltered by the so-called ‘ontological turn’ in the social sciences, organisational analysis has paid special attention to artefacts. Nevertheless, there is still a dominant account grounded in a dichotomist view of the subject-object relationship either in teleological (mind-body) or in hylomorfic (form-matter) terms when analysing organising practices. On the contrary, our argument is based on non-dualistic approaches in an attempt to foreground relational aspects of practices.From a practice-based approach, the article addresses the role of three ‘prototypes’ aimed at the management of the ‘air’ by citizenship, in the re-configuration of bodies, technics and ethical-political engagement. Specifically, it focuses on the normative dimensions of organising by which knowledges, materials and values converge in the open-ended process of prototyping. The argument is deployed by relying on qualitative research based on multi-sited ethnographic fieldwork, developed both at different workshops and by online ethnography.The main aim of the article is to show how bodies and artefacts are mutually in/trans/formed when negotiating the social implications for the ontological category of ‘air’. In doing so, the concept of ‘informal infrastructure’ is proposed to account for those practices (which appear somewhat contingent, mundane or, at best, taken for granted) by which agents do not only commit to a particular ethical implication embedded in the category of ‘air’, as a symbolic result, but also to distinctive ways of practicing organisation as a political process of performing materiality. To this end, adopting the analytical concept of ‘informal infrastructure’ allows to simultaneously consider both the formal and informal aspects that emerge in these collaboration-driven practices, as well as to address their effects on the maintenance within and expansion into other networks.
Robust automatic hexahedral cartilage meshing framework enables population-based computational studies of the knee
Authors: Gibbons Kalin D. , Malbouby Vahid , Alvarez Oliver , Fitzpatrick Clare K. 
Published: December 2022

Osteoarthritis of the knee is increasingly prevalent as our population ages, representing an increasing financial burden, and severely impacting quality of life. The invasiveness of in vivo procedures and the high cost of cadaveric studies has left computational tools uniquely suited to study knee biomechanics. Developments in deep learning have great potential for efficiently generating large-scale datasets to enable researchers to perform population-sized investigations, but the time and effort associated with producing robust hexahedral meshes has been a limiting factor in expanding finite element studies to encompass a population. Here we developed a fully automated pipeline capable of taking magnetic resonance knee images and producing a working finite element simulation. We trained an encoder-decoder convolutional neural network to perform semantic image segmentation on the Imorphics dataset provided through the Osteoarthritis Initiative. The Imorphics dataset contained 176 image sequences with varying levels of cartilage degradation. Starting from an open-source swept-extrusion meshing algorithm, we further developed this algorithm until it could produce high quality meshes for every sequence and we applied a template-mapping procedure to automatically place soft-tissue attachment points. The meshing algorithm produced simulation-ready meshes for all 176 sequences, regardless of the use of provided (manually reconstructed) or predicted (automatically generated) segmentation labels. The average time to mesh all bones and cartilage tissues was less than 2 min per knee on an AMD Ryzen 5600X processor, using a parallel pool of three workers for bone meshing, followed by a pool of four workers meshing the four cartilage tissues. Of the 176 sequences with provided segmentation labels, 86% of the resulting meshes completed a simulated flexion-extension activity. We used a reserved testing dataset of 28 sequences unseen during network training to produce simulations derived from predicted labels. We compared tibiofemoral contact mechanics between manual and automated reconstructions for the 24 pairs of successful finite element simulations from this set, resulting in mean root-mean-squared differences under 20% of their respective min-max norms. In combination with further advancements in deep learning, this framework represents a feasible pipeline to produce population sized finite element studies of the natural knee from subject-specific models.
Large-conductance Ca2 +-activated K+ channel β1-subunit maintains the contractile phenotype of vascular smooth muscle cells
Authors: Wang Meili , Li Shuanglei , Liu Hongshan , Liu Mingyuan , Zhang Jin , Wu Yang , Xiao Cangsong , Huang Haixia 
Published: December 2022

BackgroundVascular smooth muscle cells (VSMCs) phenotype switching is very important during the pathogenesis and progression of vascular diseases. However, it is not well understood how normal VSMCs maintain the differentiated state. The large-conductance Ca2+-activated K+ (BKCa) channels are widely expressed in VSMCs and regulate vascular tone. Nevertheless, there is limited understanding of the role of the BKCa channel in modulation of the VSMC phenotype.Methods and resultsWe assessed BKCa channel expression levels in normal and injured carotid arteries from rats of the balloon-injury model. A strong decrease of BKCa-β1 was seen in the injured carotid arteries, accompanied by a parallel decrease of the VSMC contractile markers. BKCa-β1 in primary rat aortic VSMCs was decreased with the increase of passage numbers and the stimulation of platelet-derived growth factor (PDGF)-BB. Conversely, transforming growth factor β upregulated BKCa-β1. Meanwhile, the BKCa-β1 level was positively associated with the levels of VSMC contractile proteins. Intravenous injection of PDGF-BB induced downregulation of BKCa-β1 expression in the carotid arteries. Knockdown of BKCa-β1 favored VSMC dedifferentiation, characterized by altered morphology, abnormal actin fiber organization, decreased contractile proteins expression and reduced contractile ability. Furthermore, the resultant VSMC dedifferentiated phenotype rendered increased proliferation, migration, enhanced inflammatory factors levels, and matrix metalloproteinases activity. Studies using primary cultured aortic VSMCs from human recapitulated key findings. Finally, protein level of BKCa-β1 was reduced in human atherosclerotic arteries.ConclusionBKCa-β1 is important in the maintenance of the contractile phenotype of VSMCs. As a novel endogenous defender that prevents pathological VSMC phenotype switching, BKCa-β1 may serve as a potential therapeutic target for treating vascular diseases including post-injury restenosis and atherosclerosis.
Impact of turbulence on magnetic alignment in sediments
Authors: Philippe Édouard G. H. , Valet Jean-Pierre , St-Onge Guillaume , Egli Ramon 
Published: December 2022

Rapidly deposited layers (RDL) such as turbidites or hyperpycnites are mostly studied for their sedimentological properties, but are carefully avoided in paleomagnetic studies due to the disturbances caused by such sudden and rapid sediment accumulation. Therefore, these layers can also be seen as potential indicators of sediment parameters susceptible of affecting the alignment of magnetic grains and ultimately the acquisition of the natural remanent magnetization (NRM). We have compiled 13 Holocene rapidly deposited layers from core MD99-2222 in the Saguenay Fjord, eastern Canada (St-Onge and al., 2004) with varying thicknesses (from 7.1 cm to 1,510 cm) and 4 Quaternary turbidites of different origins, to document the influence of sedimentary and magnetic parameters on natural remanent magnetization acquisition. We found a logarithmic relationship between rapidly deposited layers thickness on the one hand, and the amplitude of inclination changes and magnetic grain sizes on the other. Inclination and magnetic grain sizes are themselves correlated to each other by a logarithmic law. As there is no relationship between inclination deviation and stratigraphic depth, compaction alone cannot account for such large effects on inclination. Flocculation is grain size sensitive, but it is expected to affect mainly the natural remanent magnetization intensity, rather than its direction. Turbulence that prevails during the rapid deposition of sediments during such events is most likely the dominant factor.
Interventions associated with brown adipose tissue activation and the impact on energy expenditure and weight loss: A systematic review
Authors: Perez Luis C. , Perez Laura T. , Nene Yash , Umpierrez Guillermo E. , Davis Georgia M. , Pasquel Francisco J. 
Published: December 2022

BackgroundBrown adipose tissue (BAT) plays a role in modulating energy expenditure. People with obesity have been shown to have reduced activation of BAT. Agents such as β-agonists, capsinoids, thyroid hormone, sildenafil, caffeine, or cold exposure may lead to activation of BAT in humans, potentially modulating metabolism to promote weight loss.MethodsWe systematically searched electronic databases for clinical trials testing the effect of these agents and cold exposure on energy expenditure/thermogenesis and the extent to which they may impact weight loss in adults.ResultsA total of 695 studies from PubMed, Web of Science, and Medline electronic databases were identified. After the removal of duplicates and further evaluation, 47 clinical trials were analyzed. We observed significant heterogeneity in the duration of interventions and the metrics utilized to estimate thermogenesis/energy expenditure. Changes observed in energy expenditure do not correlate with major weight changes with different interventions commonly known to stimulate thermogenesis. Even though cold exposure appears to consistently activate BAT and induce thermogenesis, studies are small, and it appears to be an unlikely sustainable therapy to combat obesity. Most studies were small and potential risks associated with known side effects of some agents such as β-agonists (tachycardia), sibutramine (hypertension, tachycardia), thyroid hormone (arrhythmias) cannot be fully evaluated from these small trials.ConclusionThough the impact of BAT activation and associated increases in energy expenditure on clinically meaningful weight loss is a topic of great interest, further data is needed to determine long-term feasibility and efficacy.
Occupational and domestic physical activity and diabetes risk in adults: Results from a long-term follow-up cohort
Authors: Wang Jialu , He Liyun , Yang Na , Li Ziyi , Xu Lingling , Li Wei , Ping Fan , Zhang Huabing , Li Yuxiu 
Published: December 2022

BackgroundPhysical activity (PA) has been associated with decreased incidence of diabetes. However, few studies have evaluated the influence of occupational and domestic PA on the risk of diabetes with a long-term follow-up. We aimed to examine the association between occupational and domestic PA and the risk of diabetes in a long-term prospective cohort of Chinese adults.MethodsA total of 10,343 adults who were followed up in the China Health and Nutrition Survey from 1997 to 2015 were included in our analysis. Occupational and domestical PA were collected with detailed seven-day data and were converted into metabolic equivalents values. Total PA included occupational, domestic, transportation, and leisure time PA. Diabetes cases were identified by self-reported doctor/health professional diagnosis of diabetes, fasting blood glucose ≥7.0 mmol/L, and glycosylated hemoglobin (HbA1c) ≥6.5%. Cox proportional hazards models were used to calculate hazard ratios (HR) and 95% confidence intervals (CI).ResultsDuring up to 18 years of follow-up (median 10 years), there were 575 diabetes cases documented. Occupational PA accounted for the majority of total PA (68%) in Chinese population, followed by domestic PA (25%). With adjustments for possible covariates, the highest quartiles of total PA (HR, 0.728 [95% CI, 0.570–0.929]) and occupational PA (HR, 0.765 [95% CI, 0.596–0.982]) were significantly associated with a lower risk of diabetes compared with lowest quartiles. The association between domestic PA and the risk of diabetes was insignificant (P &gt;0.05).ConclusionHigher levels of occupational PA were associated with a decreased risk of diabetes risk in the Chinese population. Domestic PA was not associated with the incidence of diabetes.