bluuebunny/crossref_metadata_2025_split huggingface dataset:
A single‐center PICU present status survey of pediatric sepsis‐related acute respiratory distress syndrome
Authors: Zhou Liang , Li Shaojun , Tang Tian , Yuan Xiu , Tan Liping 
Published: April 2022

AbstractBackgroundTo describe the incidence, clinical features, outcomes, and mortality risk factors of sepsis associated with acute respiratory distress syndrome (ARDS) in pediatric patients.MethodsPatients were included in the study if they met the 2005 version of the International Pediatric Sepsis Consensus Conference and met the Pediatric Acute Lung Injury Consensus Conference (PALICC) definition within 48 h of sepsis diagnosis. Patients were classified as mild, moderate, and severe by the worst oxygenation index (OI) within 72 h of sepsis‐related ARDS diagnosis.ResultsBetween January 1, 2015 and March 13, 2020, 9836 patients were admitted to the pediatric intensive care unit (PICU) of the Children's Hospital of Chongqing Medical University and 828 (8.4%) were identified with sepsis and 203 (24.5%) met the PALICC definition with a PICU mortality rate of 24.6% (50/203) and a 90‐day mortality rate of 40.9% (83/203). After adjusting for septic shock, the pediatric logistic organ dysfunction 2 (PELOD‐2), high‐frequency oscillation ventilation (HFOV), and continuous renal replacement therapy (CRRT), the variables that retained an independent association with increased 90‐day mortality in pediatric sepsis‐related ARDS included ARDS severity, the pediatric risk of mortality III (PRISM III), number of organ dysfunctions and use of vasoactive drug types during PICU stay.ConclusionsPICU mortality in pediatric sepsis‐related ARDS was high (24.6%) and severity of hypoxemia based on the worst OI value 72 h after meeting the PALICC definition accurately stratified the patient outcomes. ARDS severity, PRISM III score, comorbid multiorgan dysfunction, and use of multiple vasoactive drugs during PICU stay were independent risk factors for 90‐day mortality in pediatric sepsis‐related ARDS.
Dimeric assembly of human Suv3 helicase promotes its RNA unwinding function in mitochondrial RNA degradosome for RNA decay
Authors: Jain Monika , Golzarroshan Bagher , Lin Chia‐Liang , Agrawal Sashank , Tang Wei‐Hsuan , Wu Chiu‐Ju , Yuan Hanna S. 
Published: April 2022

AbstractHuman Suv3 is a unique homodimeric helicase that constitutes the major component of the mitochondrial degradosome to work cooperatively with exoribonuclease PNPase for efficient RNA decay. However, the molecular mechanism of how Suv3 is assembled into a homodimer to unwind RNA remains elusive. Here, we show that dimeric Suv3 preferentially binds to and unwinds DNA–DNA, DNA–RNA, and RNA–RNA duplexes with a long 3′ overhang (≥10 nucleotides). The C‐terminal tail (CTT)‐truncated Suv3 (Suv3ΔC) becomes a monomeric protein that binds to and unwinds duplex substrates with ~six to sevenfold lower activities relative to dimeric Suv3. Only dimeric Suv3, but not monomeric Suv3ΔC, binds RNA independently of ATP or ADP, and is capable of interacting with PNPase, indicating that dimeric Suv3 assembly ensures its continuous association with RNA and PNPase during ATP hydrolysis cycles for efficient RNA degradation. We further determined the crystal structure of the apo‐form of Suv3ΔC, and SAXS structures of dimeric Suv3 and PNPase–Suv3 complex, showing that dimeric Suv3 caps on the top of PNPase via interactions with S1 domains, and forms a dumbbell‐shaped degradosome complex with PNPase. Overall, this study reveals that Suv3 is assembled into a dimeric helicase by its CTT for efficient and persistent RNA binding and unwinding to facilitate interactions with PNPase, promote RNA degradation, and maintain mitochondrial genome integrity and homeostasis.
The impact of cardiovascular comorbidities associated with risk for left heart disease on idiopathic pulmonary arterial hypertension: Data from the Hellenic Pulmonary Hypertension Registry (HOPE)
Authors: Arvanitaki Alexandra , Vrana Elena , Boutsikou Maria , Anthi Anastasia , Apostolopoulou Sotiria , Avgeropoulou Aikaterini , Demerouti Eftychia , Patrianakos Alexandros , Karyofyllis Panagiotis , Mitrouska Ioanna , Mouratoglou Sophia A. , Naka Katerina K. , Orfanos Stylianos E. , Panagiotidou Evangelia , Pitsiou Georgia , Rammos Spyridon , Stanopoulos Ioannis , Thomaidi Adina , Frogoudaki Alexandra , Boutou Afroditi , Anastasiadis George , Brili Styliani , Tsangaris Iraklis , Tsiapras Dimitrios , Voudris Vassilios , Manginas Athanasios , Giannakoulas George 
Published: April 2022

AbstractWhereas younger female patients were diagnosed with idiopathic pulmonary arterial hypertension (IPAH) in 1980s, it is now frequently encountered in elderly patients with cardiovascular comorbidities (CVCs) associated with increased risk for left heart disease. We present data until November 2019 regarding specific features and clinical outcomes of IPAH population from the Hellenic Pulmonary Hypertension Registry (HOPE). Patients were divided into two groups based on the presence of ≥ or <3 CVCs, arterial hypertension, diabetes mellitus, obesity, presence of coronary artery disease, or atrial fibrillation. Overall, 77 patients with IPAH (55.1 [interquartile range, IQR: 24.1] years, 62.8% women) have been recorded. Fifteen patients (19.2%) had ≥3 CVCs, while 25 (32%) were over 65 years old. Patients with ≥3 CVCs were older, presented an almost equal female to male ratio, walked less in 6‐min walk test, and had lower mean arterial pulmonary pressure and pulmonary vascular resistance at baseline than patients with less CVCs. Fewer patients with ≥3 CVCs received PAH‐specific treatment compared to patients with less comorbidities (n = 11 [73.3%] versus n = 58 [95.5%], p = 0.02). During a median follow‐up period of 3.8 (IQR: 2.7) years, 18 patients died (all‐cause mortality 24.3%). Male sex and older age were independent predictors of mortality and/or lung transplantation, while CVCs did not have a significant impact on clinical outcomes. In this nationwide, register‐based study, the epidemiology of IPAH involves older patients with CVCs, who seem to have less hemodynamic compromise, but worse functional impairment and are treated less aggressively with PAH pharmacotherapy.
Structures, electronic and thermodynamic properties of NiB2n (n = 7–11) and their anions: A theoretical study
Authors: Li Chenggang , Cui Yingqi , Tian Hao , Shao Qinqin , Zhang Jie , Shen Zigang , Ren Baozeng 
Published: April 2022

AbstractParticle Swarm Optimization (CALYPSO) searching method and density functional theory (DFT) were used to study structures, electronic, and thermodynamic properties of NiB2n0/− (n = 7–11) clusters at the TPSSh/6‐311 + G(d) level of theory. Results found that the lowest energy structures possess a Ni atom‐centered double ring tubular boron structures, NiB180/− except. Relative stabilities were analyzed via computing their vertical ionization potentials (VIP), vertical electronic affinity (VEA), adiabatic electronic affinity (AEA), HOMO‐LUMO gaps and hardness. The infrared spectra, Raman spectra and photoelectron spectra were computationally simulated to facilitate their experimental characterizations. At last, aromatic properties (nucleus independent chemical shift and anisotropy of the current induced density) and thermodynamic properties (enthalpy and entropy) with temperature were discussed in detail for studied systems.
Application of 5G technology to conduct tele‐surgical robot‐assisted laparoscopic radical cystectomy
Authors: Yang Xuecheng , Wang Yonghua , Jiao Wei , Li Jianmin , Wang Bingqiang , He Long , Chen Yongjian , Xuesong Gao  , Li Zhaoyu , Zhang Yu , Li Huanting , Wang Chen , Luo Lei , Song Mengqi , Lijiang Sun  , Zheng Jilu , Weidong Guo  , Yu Cao  , Zongyi Yu  , Xiao Hu  , Xuemei Ding  , Fengju Guan  , Wei Feng  , Kun Li  , Linlin Li  , Xinjuan Kong  , Lili Wei  , Hao Wang  , Bin Wei  , Hongmei Xue  , Wang Xinsheng , Zhang Guiming , Dong Qian , Niu Haitao 
Published: April 2022

AbstractBackgroundThe aim of this study was to test the effectiveness, safety and stability of the 5G communication technology in clinical laparoscopic telesurgery.MethodsAn ultra‐remote radical cystectomy (network communication distance of nearly 3000 km) was performed on patient diagnosed with T2N0M0 stage bladder cancer using a domestically produced “MicroHand” surgical robot.ResultsThe network delay, operative time, blood loss, intraoperative complications, postoperative recovery, and hospitalisation time were recorded. The 5G network was used throughout the operation, with an average total delay of 254 ms. The operation went well and the patient recovered smoothly.ConclusionsUltra‐remote clinical laparoscopic surgery can be performed safely and smoothly. More importantly, our model can provide insights for promoting the future development of telesurgery in China.
The relationship of sense of school belonging to physics attitude among high school students in advanced physics courses
Authors: Smith Thomas J. , Hong Zuway‐R , Hsu Wen‐Yi , Lu Ying‐Yan 
Published: April 2022

AbstractThis study examined how high school students' attitudes toward advanced physics were predicted by their sense of school belonging, and how gender moderated this relationship. The Trends in International Math and Science (TIMSS) 2015 Advanced data, consisting of responses from 12th grade students enrolled in advanced physics courses among nine countries were used for analysis. Results indicated that students' sense of school belonging significantly predicted the extent that students liked learning advanced physics and their valuing of advanced physics and, among Lebanese students, it was the most important predictor. Additionally, the relationship between students' sense of school belonging and liking advanced physics was stronger for males than for females in Norway and Sweden, while the relationship between the sense of school belonging and valuing advanced physics was stronger for males than females in France and Sweden.
Recent Advances in Bimetallic Catalysts for Hydrogen Production from Ammonia
Authors: Khan Wasim U , Alasiri Hassan S , Ali Syed A , Hossain Mohammad M 
Published: April 2022

AbstractThe emerging concept of the hydrogen economy is facing challenges associated with hydrogen storage and transport. The utilization of ammonia as an energy (hydrogen) carrier for the on‐site generation of hydrogen via ammonia decomposition has gained attraction among the scientific community. Ruthenium‐based catalysts are highly active but their high cost and less abundance are limitations for scale‐up application. Therefore, combining ruthenium with cheaper transition metals such as nickel, cobalt, iron, molybdenum, etc., to generate metal‐metal (bimetallic) surfaces suitable for ammonia decomposition has been investigated in recent years. Herein, the recent trends in developing bimetallic catalyst systems, the role of metal type, support materials, promoter, synthesis techniques, and the investigations of the reaction kinetics and mechanism for ammonia decomposition have been reviewed.
A Review on SAPO‐34 Zeolite Materials for CO2 Capture and Conversion
Authors: Usman Muhammad , Ghanem Akram S. , Niaz Ali Shah Syed , Garba Mustapha D. , Yusuf Khan Mohd , Khan Sikandar , Humayun Muhammad , Laeeq Khan Asim 
Published: April 2022

AbstractAmong several known zeolites, silicoaluminophosphate (SAPO)‐34 zeolite exhibits a distinct chemical structure, unique pore size distribution, and chemical, thermal, and ion exchange capabilities, which have recently attracted considerable research attention. Global carbon dioxide (CO2) emissions are a serious environmental issue. Current atmospheric CO2 level exceeds 414 parts per million (ppm), which greatly influences humans, fauna, flora, and the ecosystem as a whole. Zeolites play a vital role in CO2 removal, recycling, and utilization. This review summarizes the properties of the SAPO‐34 zeolite and its role in CO2 capture and separation from air and natural gas. In addition, due to their high thermal stability and catalytic nature, CO2 conversions into valuable products over single metal, bi‐metallic, and tri‐metallic catalysts and their oxides supported on SAPO‐34 were also summarized. Considering these accomplishments, substantial problems related to SAPO‐34 are discussed, and future recommendations are offered in detail to predict how SAPO‐34 could be employed for greenhouse gas mitigation.
Color‐blind or racially conscious? How college science faculty make sense of racial/ethnic underrepresentation in STEM
Authors: Russo‐Tait Tatiane 
Published: April 2022

AbstractScholars across disciplines and throughout PK‐20 education have argued that color‐blind ideology works to perpetuate racial inequities in education via policies, research, curriculum, instruction, and student‐teacher interactions. This study explores an underexamined issue in relation to color‐blind ideology in STEM education. Specifically, it examines how a sample of college science faculty members use color‐blind framings to make sense of the underrepresentation of Black, Indigenous, and Latinx students in their fields. Interviews were conducted with 42 professors (majority tenured/tenure‐track, white, male, and continuing generation to college) in a College of Sciences at a research‐intensive, historically white institution in the United States. Thematic analysis showed that while many faculty members implicated systemic racism in their sense making about the underrepresentation of racially minoritized students in STEM, the majority used color‐blind frames (abstract liberalism, cultural racism, and minimization of racism) by focusing on individual behaviors and choices, cultural deficits, under‐preparation, and poverty. Consistent with the research on color‐blind ideology, professors were able to explain racial phenomena without implicating race/racism, which allowed them to absolve themselves from responsibility in addressing racial inequality issues in higher education. Faculty members who made sense of underrepresentation through systemic racism framings tended to recognize that they had a role to play in ameliorating these issues for students of color. These findings have implications for future research and professional development efforts.
Talent management in English universities during the coronavirus pandemic
Authors: Martin Lynn , Dabic Marina , Lord Gemma 
Published: April 2022

AbstractThis article reports a longitudinal study exploring talent management, through narratives provided by a group of managers of doctoral programmes in eight UK universities during the 2020 coronavirus outbreak. These managers were also academics, researchers and doctoral supervisors and their perspectives were gathered before and during “lockdown,” and then into the subsequent confused period of semi‐lockdown / second lockdown, as cases of Coronavirus increased again in late 2020. Changing socio‐economic circumstances, together with the added pressures of family responsibilities, impacted on participants' perceptions of changing roles and relationships during the pandemic. Over 12 months, six semi‐structured online interviews (each lasting between 50 and 120 minutes) were conducted, using available platforms, with intervening emails. The narratives showed both formal and informal “talent management methods” and emphasized the need to use both to attract and retain international students.
A novel holographic quantum phase transition and butterfly velocity
Authors: Fu Guoyang , Wang Xi-Jing , Liu Peng , Zhang Dan , Kuang Xiao-Mei , Wu Jian-Pin 
Published: April 2022

Abstract
In this paper, we make a systematical and in-depth exploration on the phase structure and the behaviors of butterfly velocity in an Einstein-Maxwell-dilaton-axions (EMDA) model. Depending on the model parameter, there are two kinds of mechanisms driving quantum phase transition (QPT) in this model. One is the infrared (IR) geometry to be renormalization group (RG) unstable, and the other is the strength of lattice deformation leading to some kind of bifurcating solution. We also find a novel QPT in the metal phases. The study on the behavior of the butterfly velocity crossing QPT indicates that the butterfly velocity or its first derivative exhibiting local extreme depends on the QPT mechanism. Further, the scaling behaviors of the butterfly velocity in the zero-temperature limit confirm that different phases are controlled by different IR geometries. Therefore, the butterfly velocity is a good probe to QPT and it also provides a possible way to study QPT beyond holography.
Dualities in quantum integrable many-body systems and integrable probabilities. Part I
Authors: Gorsky A. , Vasilyev M. , Zotov A. 
Published: April 2022

Abstract
In this study we map the dualities observed in the framework of integrable probabilities into the dualities familiar in a realm of integrable many-body systems. The dualities between the pairs of stochastic processes involve one representative from Macdonald-Schur family, while the second representative is from stochastic higher spin six-vertex model of TASEP family. We argue that these dualities are counterparts and generalizations of the familiar quantum-quantum (QQ) dualities between pairs of integrable systems. One integrable system from QQ dual pair belongs to the family of inhomogeneous XXZ spin chains, while the second to the Calogero-Moser-Ruijsenaars-Schneider (CM-RS) family. The wave functions of the Hamiltonian system from CM-RS family are known to be related to solutions to (q)KZ equations at the inhomogeneous spin chain side. When the wave function gets substituted by the measure, bilinear in wave functions, a similar correspondence holds true. As an example, we have elaborated in some details a new duality between the discrete-time inhomogeneous multispecies TASEP model on the circle and the quantum Goldfish model from the RS family. We present the precise map of the inhomogeneous multispecies TASEP and 5-vertex model to the trigonometric and rational Goldfish models respectively, where the TASEP local jump rates get identified as the coordinates in the Goldfish model. Some comments concerning the relation of dualities in the stochastic processes with the dualities in SUSY gauge models with surface operators included are made.
Dynamics of the stream–lake transitional zone affect littoral lake metabolism
Authors: Ward Nicole K. , Brentrup Jennifer A. , Richardson David C. , Weathers Kathleen C. , Hanson Paul C. , Hewett Russell J. , Carey Cayelan C. 
Published: April 2022

AbstractLake ecosystems, as integrators of watershed and climate stressors, are sentinels of change. However, there is an inherent time-lag between stressors and whole-lake response. Aquatic metabolism, including gross primary production (GPP) and respiration (R), of stream–lake transitional zones may bridge the time-lag of lake response to allochthonous inputs. In this study, we used high-frequency dissolved oxygen data and inverse modeling to estimate daily rates of summer epilimnetic GPP and R in a nutrient-limited oligotrophic lake at two littoral sites located near different major inflows and at a pelagic site. We examined the relative importance of stream variables in comparison to meteorological and in-lake predictors of GPP and R. One of the inflow streams was substantially warmer than the other and primarily entered the lake’s epilimnion, whereas the colder stream primarily mixed into the metalimnion or hypolimnion. Maximum GPP and R rates were 0.2–2.5 mg O2 L−1 day−1 (9–670%) higher at littoral sites than the pelagic site. Ensemble machine learning analyses revealed that > 30% of variability in daily littoral zone GPP and R was attributable to stream depth and stream–lake transitional zone mixing metrics. The warm-stream inflow likely stimulated littoral GPP and R, while the cold-stream inflow only stimulated littoral zone GPP and R when mixing with the epilimnion. The higher GPP and R observed near inflows in our study may provide a sentinel-of-the-sentinel signal, bridging the time-lag between stream inputs and in-lake processing, enabling an earlier indication of whole-lake response to upstream stressors.
Full ellipsoid embeddings and toric mutations
Authors: Casals Roger , Vianna Renato 
Published: April 2022

AbstractThis article introduces a new method to construct volume-filling symplectic embeddings of 4-dimensional ellipsoids by employing polytope mutations in toric and almost toric varieties. The construction uniformly recovers the full sequences for the Fibonacci Staircase of McDuff–Schlenk, the Pell Staircase of Frenkel–Müller and the Cristofaro-Gardiner–Kleinman Staircase, and adds new infinite sequences of ellipsoid embeddings. In addition, we initiate the study of symplectic-tropical curves for almost toric fibrations and emphasize the connection to quiver combinatorics.
Fast spatial behavior in higher order in time equations and systems
Authors: Fernández José R. , Quintanilla Ramón 
Published: April 2022

AbstractIn this work, we consider the spatial decay for high-order parabolic (and combined with a hyperbolic) equation in a semi-infinite cylinder. We prove a Phragmén-Lindelöf alternative function and, by means of some appropriate inequalities, we show that the decay is of the type of the square of the distance to the bounded end face of the cylinder. The thermoelastic case is also considered when the heat conduction is modeled using a high-order parabolic equation. Though the arguments are similar to others usually applied, we obtain new relevant results by selecting appropriate functions never considered before.
Innovationsfonds und Primärversorgung – Welche Erwartungen und Erfahrungen vertreten Hausärzt*innen in Bezug auf die Teilnahme an innovativen Versorgungsmodellen?
Authors: Wangler Julian , Jansky Michael 
Published: April 2022

Zusammenfassung
Hintergrund
Zur Verbesserung der medizinischen Versorgung wurde im Jahr 2015 der Innovationsfonds eingerichtet. Damit Interventionen bzw. neue Versorgungsformen erprobt und perspektivisch in die Regelversorgung übernommen werden können, bedarf es der Einbeziehung der allgemeinmedizinischen Versorgung.

Ziel der Arbeit
Die Studie exploriert hausärztliche Einstellungen, teilnahmerelevante Erwartungen und Erfahrungen mit Blick auf Innovationsfondsprojekte.

Methoden
Zwischen Juli und Oktober 2021 wurden sämtliche 13.170 als Behandler*innen aktive Hausärzt*innen in Baden-Württemberg, Hessen und Rheinland-Pfalz zu einer Onlinebefragung eingeladen. 3556 vollständig ausgefüllte Fragebögen gingen in die Auswertung ein (Rücklauf: 27 %). Neben der deskriptiven Analyse kam zur Feststellung von signifikanten Unterschieden zwischen 2 Gruppen ein t-Test bei unabhängigen Stichproben zum Einsatz.

Ergebnisse
83 % der Befragten kennen den Innovationsfonds. Die Befragten verbinden ihn mehrheitlich mit Chancen und Potenzialen (u. a. Intensivierung anwendungsnaher Versorgungsforschung, unabhängige Finanzierung, Einbeziehung der Primärversorgung). Dennoch sind sich viele Hausärzt*innen unsicher, inwiefern speziell die Primärversorgung längerfristig vom Innovationsfonds wird profitieren können. Hinsichtlich der Bereitschaft zur Mitwirkung an Innovationsfondsstudien zeigen sich die Befragten gespalten. Befragte, die bereits an Innovationsfondsprojekten teilgenommen haben (24 %), ziehen eine überwiegend positive Bilanz (Nutzen der Intervention, Aufwand-Nutzen-Verhältnis). Dennoch werden auch Hürden und Belastungsfaktoren berichtet, etwa Dokumentationspflichten und Eingriffe in Praxisabläufe.

Diskussion
Um die Attraktivität des Innovationsfonds für die hausärztliche Versorgung zu erhöhen, gilt es, die Hausarztkonformität von Projekten umfassend sicherzustellen, v. a. mit Blick auf ärztliche Entscheidungsspielräume, die Limitierung von Dokumentationspflichten, die Gewährleistung von Praxisroutinen, eine stärkere Involvierung in die Forschungsplanung sowie eine Aufwertung des hausärztlichen Settings.