bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment of Dyslipidemia in the Elderly
Authors: Карпова И.С. , Суджаева О.А. , Кравченко А.В. , Кошлатая О.В. , Спирина О.В. 
Published: March 2022

В статье приведен обзор литературы, посвященной диагностике и лечению дислипидемий у лиц пожилого и старческого возраста. Проанализированы данные о значимости аполипопротеинов А и В, а также липопротеина А в развитии атерогенной дислипидемии у пожилых пациентов. Проведен анализ значимости коэнзима Q в развитии синдрома старческой астении, в том числе и при проведении терапии статинами. Рассмотрены результаты многоцентровых клинических исследований, посвященных влиянию статинов на развитие сердечно-сосудистых осложнений у лиц пожилого возраста, ранее не имевших диагностированных сердечно-сосудистых заболеваний. Также приведены данные о влиянии статинотерапии на частоту развития новых кардиоваскулярных заболеваний у лиц, имевших их ранее, а также на частоту развития сердечно-сосудистых осложнений у пациентов пожилого возраста, имевших диагностированную патологию сердца и сосудов. Отдельно освещены вопросы безопасности использования статинов у пожилых пациентов. Приведены рекомендации Европейского общества кардиологов и Евразийской ассоциации кардиологов по коррекции дислипидемии у лиц старше 65 и 75 лет.
The article provides a review of literature on the diagnosis and treatment of dyslipidemia in the elderly. The data on the significance of apolipoproteins A and B, as well as lipoprotein A in the development of atherogenic dyslipidemia in elderly patients are analyzed. The analysis of the significance of coenzyme Q in the development of senile asthenia syndrome, including during statin therapy, was carried out. The results of multicenter clinical studies on the effect of statins on the development of cardiovascular complications in elderly people, who previously had no diagnosed cardiovascular diseases, are considered. The data are also given on the effect of statin therapy on the incidence of new cardiovascular diseases in people, who previously had it, as well as on the incidence of cardiovascular complications in elderly patients, who have a diagnosed pathology of the heart and vessels. The issues of safety of using statins in elderly patients are highlighted. The recommendations of the European Society of Cardiology and the Eurasian Association of Cardiology on the problem of correcting dyslipidemia in people over 65 and 75 years are given.
Ischemic Heart Disease and Related Diseases in People of the Older Age Group: Predicting Life Expectancy
Authors: Войнаровская Г.П. , Асанов Э.О. 
Published: March 2022

Цель. Определение прогностического значения основных сопутствующих заболеваний внутренних органов у пациентов с ишемической болезнью сердца (ИБС) пожилого и старческого возраста.Материалы и методы. Проведен ретроспективный анализ историй болезней и сформирована выборка из 236 пациентов с ИБС старше 60 лет, которые наблюдались в ГУ «Институт геронтологии им. Д.Ф. Чеботарева НАМНУ» в 1997–2019 годах и умерли вследствие кардиоваскулярного события.Результаты. Развитие сопутствующих заболеваний (артериальная гипертензия (АГ), сахарный диабет 2-го типа (СД), хроническое обструктивное заболевание легких (ХОЗЛ), дислипидемия) оказывает существенное влияние на снижение продолжительности жизни у пациентов с ИБС старшей возрастной группы. При этом наибольшее негативное влияние на продолжительность жизни у пациентов с ИБС пожилого и старческого возраста оказывает артериальная гипертензия и сахарный диабет. Несколько меньше снижают продолжительность жизни у пациентов с ИБС пожилого и старческого возраста дислипидемия и ХОЗЛ.Выводы. Разработанные математические модели прогнозирования продолжительности жизни пациентов с ИБС пожилого и старческого возраста могут быть использованы в клинической практике при проведении лечебно-диагностического процесса, для оценки эффективности лечебных и реабилитационных мероприятий, а также для разработки профилактических программ.
Purpose. Determination of the prognostic value of the main concomitant diseases of the internal organs in patients with ischemic heart disease (IHD) in the elderly and senile age.Materials and methods. Retrospective analysis of the medical history was performed and a sample of 236 patients with coronary heart disease older than 60 years, who were observed at the Instituteof Gerontology named after D.F. Chebotarev of the NAMS of Ukraine in the period 1997–2019 and died as a result of a cardiovascular event.Results. The development of concomitant diseases (arterial hypertension (AH), type 2 diabetes mellitus (DM), chronic obstructive pulmonary disease (COPD), and dyslipidemia) has a significant impact on reduction of life expectancy in patients with IHD in the older age groups. Moreover, AH and DM have the greatest negative impact on life expectancy in patients with IHD of the elderly and senile age. Dyslipidemia and COPD reduce the life expectancy in patients with ischemic heart disease of the elderly and senile age slightly less.Conclusions. The developed mathematical models for predicting the life expectancy of patients with IHD of the elderly and senile age can be used in clinical practice in the treatment and diagnostic process to assess the effectiveness of treatment and rehabilitation measures, as well as to develop prevention programs.
The Use of Hophytol in the Complex of Preventiveand Therapeutic Measures in Pregnant Women with Early Toxicosis
Authors: Пересада О.А. 
Published: March 2022

В статье приводятся основные причины развития раннего токсикоза беременных, его классификация, описывается клиническая картина разных форм. Указываются основные методы современного лечения данной патологии, включающего применение антиоксиданта Хофитола.
The article presents the main reasons for the development of early toxicosis in pregnant women and its classification; the clinical picture of different forms is described. The main methods of modern treatment of this pathology, including the use of the antioxidant Hophytol, are indicated.
Molecular-Biological Factors Influencing Diagnostic Reliabilityof the Results of Laboratory Studies Based on PCR Analysis. Report II
Authors: Костюк С.А. , Полуян О.С. 
Published: March 2022

Тема лабораторных ошибок в постановке полимеразной цепной реакции (ПЦР) в режиме реального времени, или менеджмент риска ошибок, продолжает оставаться весьма актуальной и недостаточно изученной, требующей выделения отдельного направления в области применения технологий молекулярно-биологического анализа. Разрозненные, недостаточно систематизированные знания, касающиеся фундаментальных основ обеспечения процедуры молекулярно-биологического исследования, не позволяют специалистам ПЦР-лабораторий практического здравоохранения эффективно организовать работу по выявлению лабораторных ошибок, которые могут возникать на любом из этапов процедуры исследования, носить методический или аналитический характер.Разработать единую типовую модель борьбы с лабораторными ошибками при проведении ПЦР-исследований сложно, поскольку каждая лаборатория может отличаться от других по своей организационной структуре, видам оборудования, используемым реагентам, перечню видов исследований. В этой связи необходимо на основе научного анализа возможных лабораторных ошибок сформировать профессиональное мышление у врачей лабораторной диагностики, работающих в практическом здравоохранении. Этой проблеме и посвящена настоящая публикация.
The topic of laboratory errors in real-time PCR or the error risk management continues to be very relevant and insufficiently studied, requiring a separate direction in the application of molecular biological analysis technologies. Scattered, insufficiently systematized knowledge regarding the fundamental principles of the molecular biological research procedure does not allow the specialists of practical healthcare PCR laboratories to effectively organize the work on detecting laboratory errors that may occur at any stage of the research procedure, be methodical or analytical.It is difficult to develop a single standard model for combating laboratory errors during PCR studies, since each laboratory may differ from others in its organizational structure, types of equipment, reagents, and the list of types of studies. In this regard, it is necessary, on the base of the scientific analysis of possible laboratory errors, to form professional thinking among laboratory diagnostics doctors, who work in practical health care. This problem is the subject of this publication.
Anosognosia in Individuals with Aggressive Behavior, with Alcohol Dependence
Authors: Сайков А.Д. , Скугаревский О.А. 
Published: March 2022

В статье анализируются результаты собственных исследований феномена анозогнозии у пациентов с зависимостью от алкоголя с разным характером гетероагрессивного поведения в анамнезе. Проверялась гипотеза о том, связана ли агрессивность зависимых от алкоголя лиц с отрицанием у себя проблемы неконтролируемого приема алкоголя. При этом принимали во внимание сложную структуру анозогнозии, имеющую когнитивный, эмоциональный и мотивационный компоненты. Пришли к выводу, что как психологический феномен анозогнозия имеется у всех пациентов с синдромом зависимости от алкоголя. Однако у лиц, склонных к гетероагрессивному поведению, явно преобладает мотивационный компонент анозогнозии, что важно при планировании лечебных и реабилитационных мероприятий.
The article analyzes the results of our own studies of the phenomenon of anosognosia in patients with alcohol dependence with a different history of hetero-aggressive behavior. The hypothesis was tested whether the aggressiveness of alcohol-dependent individuals is associated with their denial of the problem of uncontrolled alcohol intake. At the same time, the complex structure of anosognosy, which has cognitive, emotional, and motivational components, was taken into account. We came to the conclusion that, as a psychological phenomenon, anosognosia is present in all patients with alcohol dependence syndrome. However, in individuals prone to hetero-aggressive behavior, the motivational component of anosognosia clearly prevails, which is important when planning treatment and rehabilitation measures.
Complex Rehabilitation Program for Children with Sensorineural Hearing Loss
Authors: Заставная О.М. , Попович В.И. , Войчишин Л.И. , Богославец Р.Я. 
Published: March 2022

Цель. Оценка эффективности комплексной программы реабилитации детей с сенсоневральной тугоухостью, которая включала: занятия на аппарате «Верботон», занятия с дефектологом, занятия по сенсорной интеграции, логопедический массаж и лечебную гимнастику, в которую были включены упражнения на развитие мелкой моторики рук.Материалы и методы. Нами было обследовано 32 ребенка с диагнозом «сенсоневральная тугоухость III степени». Для обследования слуха у детей мы использовали метод «гороховых проб». Для тестирования мелкой моторики рук мы использовали систему классификации BFMF (Bimanual fine motor function).Результаты. Анализируя результаты «гороховых проб», мы заметили, что у детей, которые занимались по нашей программе реабилитации, достоверно улучшился слух по сравнению с детьми группы контроля. Мы также отметили, что достоверно увеличилось количество детей основной группы, у которых улучшилась мелкая моторика рук.Выводы. Анализируя вышеописанное, мы пришли к выводу, что при систематических занятиях на аппарате «Верботон» у детей с сенсоневральной тугоухостью III степени можно значительно улучшить слух, а занятия с дефектологом, логопедом, психологом и физическим терапевтом способствуют социализации ребенка, улучшению языка, мелкой моторики и общего физического развития.
Purpose. Evaluation of the effectiveness of a comprehensive rehabilitation program for children with sensorineural hearing loss, which included the following: the classes on the Verboton apparatus, classes with defectologist, classes with sensory integration, speech therapy massage and therapeutic gymnastics with exercises for development of fine motor skills of the hands.Materials and methods. We examined 32 children with sensorineural hearing loss of the 3rd degree. For examination of hearing in children, we used the“pea test” method. We used the BFMF (Bimanual fine motor function) classification system to test motor skills of the hands.Results. Analyzing the results of the “pea tests”, we noticed that the children who took part in our rehabilitation program significantly improved their hearing if compared to the children of the control group. We also noted that there was a significant increase of the number of children in the main group in who the fine motor skills of hands improved.Conclusions. We came to the conclusion that with systematic exercises on the Verboton apparatus in children with sensorineural hearing loss of the 3rd degree, it is possible to significantly improve hearing; the lessons with defectologist, speech therapist, psychologist and physical therapist contribute to child’s socialization, language improvement, fine motor skills, and general physical development.
Pengetahuan Tentang Covid 19 Dan Sikap Tentang Vaksin Covid 19
Authors: Alfianur Alfianur 
Published: March 2022

Covid 19 merupakan penyakit infeksi yang disebabkan oleh corona virus, penyakit ini telah menjadi pandemik, Pemerintah melalui Kementerian Kesehatan (Kemenkes) tengah menggenjot pelaksanaan vaksinasi massal Covid-19 sejak awal tahun ini. Hingga April 2021, Indonesia telah mencapai angka 12,7 juta vaksinasi Dengan perolehan tersebut, Namun angka ini masih jauh jika dibandingkan dengan jumlah penduduk Indonesia saat ini yang mencapai sekitar 270 juta jiwa Tujuan dari penelitian ini adalah untuk menggambarkan tingkat pengetahuan responden tentang Covid 19 dan Sikap responden tentang vaksin covid 19. Jenis penelitian ini adalah penelitian kuantitatif dengan desain Cross sectional. Sampel penelitian ini adalah pesepeda (Goweser). Menggunakan total sampling dan pengolahan data menggunakan pendekatan statistic deskriptif (distribusi frekuensi).Hasil analisis data didapatkan Responden memiliki tingkat pengetahuan yang baik sebanyak 49 orang (94%) sisanya memiliki pengetahuan ditingkat cukup sebanyak 3 orang (6%) dan sebanyak 47 orang (90%) responden memiliki sikap positif tentang vaksin covid 19 namun masih ada sebanyak 5 orang (10%) yang masih memiliki sikap negatif tentang vaksin covid 19
Evaluation of the thermal effusivity of intermetallic compounds using a modulated thermoreflectance method
Authors: Nakamura Fumiya , Murakami Taichi , Miyake Shugo 
Published: March 2022

Abstract
In this study, we evaluated thermal properties of the matrix phase and intermetallic compounds in solder joints by a frequency-domain thermoreflectance method with high spatial resolution realized by two two laser beams and considering thermal diffusion length. The values of the thermal effusivities of a tin matrix phase (Sn matrix) and the intermetallic compounds (IMCs) in solder joints were determined for each heating frequency using calibration curves given by standard samples with known thermal properties. These measured heat effusivities of these Sn matrix and IMCs were estimated various values affected thermal conductivity of addition elements. Moreover, to convert from thermal effusivity to thermal conductivity, numerical calculations were conducted with assumed various thermal conductivity of molybdenum-reflector film on the sample surface and the volumetric heat capacity of IMCs. Finally, it is found that the apparent thermal conductivity of the Mo film was 0.5 W m−1 K−1 and the thermal conductivity of IMCs were shown 25–37 W m−1 K−1 with composition dependence clearly.
Limited current conduction due to various types of stacking faults in n-type 4H-SiC epilayers
Authors: Asada Satoshi , Murata Koichi , Tsuchida Hidekazu 
Published: March 2022

Abstract
Impacts of various types of stacking faults (SFs) on electron conduction in an n-type 4H-SiC epilayer were experimentally investigated. N-type Schottky barrier diodes were fabricated, containing a SF plane in the active area with a covering ratio of unity, whereupon the current–voltage characteristics were evaluated within a temperature range of 293–523 K. The forward current was significantly limited due to the SFs, the degree of which depended on the type of SF, and the current limitation was moderated by increasing the temperature. These results could be consistently explained by the well-known quantum well model.
Pengembangan Pembelajaran Online Menggunakan Metode Contextual Learning Berbasis Film Animasi di Masa Pandemi
Authors: Amalia Dita Rizki , Narasati Riri , Dana Raditya Danar 
Published: March 2022

Belajar adalah proses seseorang memperoleh pengetahuan, dari tidak bisa menjadi bisa. Belajar juga biasanya melibatkan antara dua individu yaitu pendidik dan peserta didik.Melalui pengalaman belajar yang telah dipersiapkan oleh pendidik di dalam nya ada proses melihat, mendengar,mengamati, dan memahami segala sesuatu yang ada di sekitar peserta didik.Dalam proses pembelajaran mata kuliah Desain Web (User Experience) dimana dalam prakteknya pendidik mengaitkan antara materi dengan situasi di lapangan dengan menggunakan model pembelajaran Contextual Teaching And Leraning membutuhkan media pembelajaran untuk dapat melakukan proses pembelajaran dengan baik. Media yang digunakan adalah media film berbasis animasi dimana mahasiswa mendapat gambaran tentang bagaimana riset dari User Experience dilakukan. Hasilnya setelah dilakukan pengujian secara statistik ditemukan bahwa data berdistribusi normal walapun hasil uji t menunjukkan H0 diterima yang berarti peningkatan nilai mahasiswa secara kognitif tidak ada perbedaan pada nilai pretest dan postest yang disebabkan oleh beberapa faktor diantaranya proses belajar yang dilakukan tidak secara langsung diakibatkan pandemi sehingga tugas pun tidak dikerjakan maksimal.
Metode Multi Attributive Border Approximation Area Comparison (MABAC) Untuk Penilaian Kinerja Dalam Pengelolaan Alokasi Dana Desa (ADD)
Authors: Handayani Cucu - , Muhsidi Adi Muhamad , Khomalia Nur Isti 
Published: March 2022

The Village Fund Allocation is one income proceed for the Village Revenue and Expenditure Budget of the rural government. For the implementation of financial governance, the Department of Community and Rural Empowerment does not yet have a performance appraisal system in managing the Fund Allocations. The Performance Appraisal System which is developed in this study aims to determine the optimality of rural governments in managing the Village Fund Allocation. The research methodology used in the study is MABAC (Multi-Attributive Border Approximation Area Comparison), a multi-alternative decision type. This method was chosen because of its stability and consistency in the solutions of decision making, compared to other decision support methods. The study was carried out on 11 villages with predetermined criteria data. From this data, an analysis is carried out resulting in values of performance assessment as well as the optimality of Fund Management.
KARAKTERISTIK WARNA L* a* b* DAN TEKSTUR DENDENG DAGING KELINCI YANG DIFERMENTASI DENGAN Lactobacillus plantarum
Authors: Fadlilah Anik , Rosyidi Djalal , Susilo Agus 
Published: March 2022

ABSTRACT
This study aims to determine the concentration of L plantarum and the best fermentation time to make fermented rabbit meat dendeng based on L*a*b color and texture of rabbit meat dendeng. The material used was rabbit meat dendeng which was fermented using L. plantarum. The method of research was a experiment of laboratory with a factorial randomized block design and repeated 3 times consisting of concentrations of L. plantarum (0%, 6%, 8%, and 10%) and fermentation time (12, 18 and 24 hours). Based on the analysis of variance, it was found that different concentrations of L. plantarum and fermentation time did not have a significant effect (P>0.05) on the dendeng color of L (brightness), a* (redness) and texture, while the concentration of L. plantarum had a significant effect (P<0.05) and the fermentation time was a significant effect (P<0.05) on the color b* (yellow). The mean of L (Brightness) of dendeng was 33.94-35.72, the mean of a* of rabbit meat dendeng was 13.72-14.63, and b* was 12.53-14.83. The mean of rabbit meat dendeng texture was 22.94-25.25 N. The concentration of L. plantarum and the fermentation time that produced the best characteristic L*a*b* color and texture dendeng was 6% with 18 hours of fermentation time.
Key words: Dendeng; Rabbit; Fermentation; Color; Texture
Wanprestasi Dalam Perjanjian Kredit Kendaraan Bermotor Serta Penyelesaian Hukumnya
Authors: Retnowati Tutiek , Darmadi Sujarwo 
Published: March 2022

Penjualan kendaraan bermotor secara kredit mengalami peningkatan seiring dengan meningkatnya pertumbuhan ekonomi di Indonesia. Peningkatan daya beli mendorong masyarakat untuk meningkatkan konsumsi. Perjanjian kredit kendaraan bermotor pada dasarnya selalu menggunakan Perusahaan Pembiayaan Konsumen yang notabene lembaga finance akan memberlakukan perjanjian jaminan dalam memberikan kredit untuk memiliki kendaraan bermotor. Perjanjian kredit kendaraan bermotor tersebut adalah sah dan mengikat. Oleh karena itu para pihak yang membuat kesepakatan dalam perjanjian tersebut harus tunduk dan patuh melaksanakan isi perjanjian yang telah disepakatinya. Jika perjanjian tersebut diingkari, atau salah satu pihak melakukan wanprestasi, maka segala akibat hukum dari perjanjian tersebut akan membebaninya. Penyelesaian wanprestasi terhadap perjanjian kredit kendaraan bermotor dapat diselesaikan dengan dua cara yaitu secara mediasi dan litigasi.
Kekerasan Fisik Yang Dilakukan Oleh Residivis Terhadap Anak Ditinjau Dari Undang-Undang Nomor 35 Tahun 2014 Tentang Perubahan Atas Undang-Undang Nomor 23 Tahun 2002 Tentang Perlindungan Anak
Authors: Pualam Cindy Febriana 
Published: March 2022

Children, as apart of the young generation, are one of the potential human resources and the successor of the nation’s goals who hold strategic roles. Children’s teenager’s protection is an act or an effort consciously made by some parties for the security and welfare, and the fulfiiment of rights thant should be received and owned by the child, even before they were born. It is protected by the law. Children’s right and obligation has become the things that must be fullfilled and worth fighting for. There is a sentence in the Child Protection Law, in which consideration, that states every child has the right to live, grow, and thrive, and they have the right for protection from violence and discrimination as mandated in the Indonesian Constitution Year 1945. In relation to the constitution, special protection towards a child as a victim of violence is regulated in Article 68 Child Protection Law. Meanwhile, the restriction of violence towards children is regulated on Article 76C Child Protection Law. Next, recidivist is the repetition of similar criminal action by the same perpetrator who has been convicted in a certain period of time. It is regulated in Article 486,487 and 488, Criminal Code where there is a heavier criminal punishment for the crime included in the articles.