bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGEMBANGAN INSTRUMEN PENILAIAN MATEMATIKA BERBASIS HOTS PADA CALON GURU SEKOLAH DASAR
Authors: Rahmawati Novia Dwi , Komarudin Komarudin , Suherman Suherman 
Published: August 2022

Penelitian ini bertujuan untuk mengembangkan instrumen penilaian matematika berbasis kemampuan berpikir tingkat tinggi (HOTS) yang valid, reliabel, dan memiliki daya beda dan tingkat kesukaran yang baik. Pengembangan soal mengacu pada model Borg dan Gall. Pengambilan data dilakukan dengan teknik angket dan tes. Instrumen penelitian terdiri dari angket kebutuhan dan tes soal matematika berbasis HOTS. Penelitian ini melibatkan 15 calon guru SD. Hasil analisis data menunjukkan bahwa instrumen penilaian matematika berbasis HOTS memperoleh skor validitas sebesar (kriteria valid), skor reliabelitas sebesar (kriteri valid), skor uji daya beda sebesar (kriteria DB yang baik), dan skor uji tingkat kesukaran sebesar (kriteria tingkat kesukaran sedang). Sehingga telah memenuhi semua kriteria uji instrument tes baik, yaitu valid, reliabel, daya beda yang baik dan tingkat kesukaran sedang. Implikasi hasil penelitian terhadap pembelajaran matematika calon guru sekolah dasar yaitu menjadi salah satu reverensi pedoman dalam mengembangkan instrument penilaian matematika dan dalam mengembangkan kemampuan berpikir tingkat tinggi caloh guru sekolah dasar.This study aims to develop a mathematical assessment instrument based on higher order thinking skills (HOTS) that is valid, reliable, and has good distinguishing power and difficulty level. The development of questions refers to the Borg and Gall models. Data collection was done by using questionnaires and tests. The research instrument consisted of a needs questionnaire and a HOTS-based math test. This study involved 15 prospective elementary school teachers. The results of data analysis showed that the HOTS-based mathematical assessment instrument obtained a validity score of (valid criterion), reliability score of (valid criterion), difference power test score of (good discrimination criteria), and the difficulty level test score is (medium difficulty criteria). So that it has met all the criteria for a good test instrument test, namely valid, reliable, good discriminating power and moderate level of difficulty. The implications of the research results on the mathematics learning of elementary school teacher candidates is to become one of the reference guidelines in developing mathematics assessment instruments and in developing high-level thinking skills for elementary school teachers.
The Evolution Model of Regional Tourism Economic Development Difference Based on Spatial Variation Function
Authors: Zhang WenJian , Ebrahim Ragab 
Published: August 2022

Abstract
The article explores the evolution of regional spatial differences and has important practical significance for promoting the coordinated development of regional tourism. The article analyzes the characteristics of the spatial evolution of the economic tourism pattern from 2010 to 2020. The study found that the development of the regional tourism economy is on the rise, and the development is not balanced. The spatial self-organization of economic development is getting stronger and stronger, and the spatial economic distribution is different. Then this article analyzes the main factors that cause this spatial distribution and proposes corresponding solutions. This provides a theoretical basis for reducing the gap in the tourism economy between regions and promoting the coordinated development of the regional tourism economy.
Higher Education Agglomeration Promoting Innovation and Entrepreneurship Based on Spatial Dubin Model
Authors: Shao Xingyuan , Bao Xiaoping , Al-Ethawi Ahlam 
Published: August 2022

Abstract
We use the panel data of innovation and entrepreneurship for global spatial autocorrelation and model selection testing. At the same time, we applied the Spatial Dubin Model (SDM) to empirically study the knowledge spillover effects of higher education campuses on regional innovation capabilities. Experimental research found that there are significant spatial differences in the innovation efficiency of universities. Specialized agglomeration can effectively improve the innovation efficiency and scale efficiency of colleges and universities. At the same time, the diversified agglomeration has no obvious effect on the innovation efficiency of colleges and universities. The accumulation of high-tech industries can effectively promote the innovation efficiency of universities. Human capital and opening to the outside world can effectively improve the innovation efficiency of universities.
Optimization of Color Matching Technology in Cultural Industry by Fractional Differential Equations
Authors: Wu Shaopeng 
Published: August 2022

Abstract
This article combines the fractional differential theory with the total variation method and applies it to defining cultural industry image color matching. At the same time, we propose a new image color matching denoising model based on fractional partial differential equations. The model achieves simultaneous denoising in the time direction and the spaceplane. Experiments have proved that the fractional partial differential equations method has more advantages than integer-order partial differential equations in denoising and reducing step effects. It can effectively improve the contrast and clarity of image color matching in the cultural industry.
Expression of bovine leukaemia virus (BLV) gp51 protein in blood and milk cells of cows with leukosis
Authors: Szczotka Maria , Kuźmak Jacek 
Published: August 2022

Abstract

Introduction
Bovine leukaemia virus (BLV) is the retroviral causative agent of enzootic bovine leukosis, the most common neoplastic disease of cattle and a serious problem worldwide. Its diagnosis is commonly by tests for antibodies recognising the p24 capsid protein and structural glycoprotein (gp) 51. With flow cytometry recently having come to veterinary immunology, applications for it may now include BLV. The study determined BLV gp51 expression in blood and milk lymphocytes of naturally infected cows by flow cytometry.

Material and Methods
Nineteen Polish Black and White Lowland breed cows aged 4–9 years and naturally infected with BLV and ten uninfected counterparts had blood and milk sampled and cultured. The immunological status of the animals was confirmed with ELISA and PCR. Dual-colour flow cytometry analysis was performed with specific monoclonal antibodies for lymphocyte cluster of differentiation (CD) markers and gp51 viral envelope protein and conjugates labelled with fluorescein isothiocyanate or phycoerythrin. Bovine leukaemia virus gp51 was confirmed in lymphocytes by immunofluorescence with anti-gp51 monoclonal antibodies.

Results
The gp51 antigen was detected in blood and milk lymphocytes of infected cows, but the percentage of cells expressing it in milk was much lower than in blood. A depleted number of CD4+ lymphocytes, an augmented number of CD8+ lymphocytes, a lower ratio of CD4+ to CD8+ and a proliferation of CD19+ immunoglobulin M+ cells were also found.

Conclusion
These proliferated cells were immature, gave no sign of a tendency to differentiation and were characterised by prolonged vitality.
Is serological monitoring a fit-for-purpose tool to assess the epidemiological situation of tuberculosis in the sylvatic species of European bison (Bison bonasus) in Poland?
Authors: Krzysiak Michał K. , Larska Magdalena , Zabost Anna , Didkowska Anna , Krajewska-Wędzina Monika , Anusz Krzysztof , Augustynowicz-Kopeć Ewa 
Published: August 2022

Abstract

Introduction
Bovine tuberculosis is one of the most dangerous zoonotic diseases. Despite the near-complete elimination of the disease from cattle breeding in Poland achieved in 2009, its re-emergence is now observed. Globally, the number of human cases is underestimated and the importance of free-living animals as reservoirs of tuberculosis is growing. As a species highly susceptible to Mycobacterium tuberculosis complex infection, the European bison (Bison bonasus) has a role in the transmission of the disease in Poland. The purpose of the investigation was to assess the epidemiological situation of tuberculosis in Polish European bison serologically.

Material and Methods
A total of 460 serum samples were collected from 436 European bison from 15 out of 26 national populations between 2013 and 2020. An M. bovis ELISA was used, and its sensitivity and specificity were assessed with an eyelid tuberculin skin test (TST) and interferon gamma release assay (IGRA).

Results

Mycobacterium bovis antibodies were detected in nine serum samples. The presence of antibodies was found in two animals from the Białowieża Forest (1.2% of the population), and one each from the Borecka Forest (2.4%) and the Warsaw Zoo (14.3%). One European bison among the 14 sampled (7.1%) from Smardzewice was positive on five occasions. Other samples from Smardzewice and the Bieszczady Mountains, where tuberculosis had previously been reported, were negative.

Conclusion
ELISA testing is an effective, easy and cost-efficient tool for monitoring of tuberculosis-naïve populations. Serological testing in tuberculosis control programmes can significantly improve the detection of infected herds. Antibody ELISAs may supplement TST and IGRA, but cannot replace them.
Israel’s changing geostrategic posture
Authors: Eiran Ehud 
Published: August 2022

Abstract
This paper analyzes Israel’s changing understanding of its geostrategic posture from its establishment in 1948 to the current era. It starts by reviewing traditional Israeli geostrategic ideas and their implementation, mostly, as reflected in the nation’s national security doctrine. The paper then investigates the effect of Israel’s territorial expansion after 1967 on Israeli ideas about geostrategy. Finally, the paper shows how changing global, regional, and technological variables in the last two decades have transformed how Israeli elites understand their geostrategic realities and how they allocate resources in response to these changing conditions.
The Use of Balanced Scorecard to Support Achievement of Business Plan in Digestive Endoscopy Center, 2013
Authors: Abdullah Murdani , Makmun Dadang , Fauzi Achmad , Santi Aan 
Published: August 2022

Background: Digestive Endoscopy Center, Cipto Mangunkusumo Hospital was established in 2011 in which the concept was developed as center of excellence (CoE). The business plan was created based on safety and patient satisfaction, fast, accurate, quality and one stop services. 2013 is the 2nd year in Digestive Endoscopy Center business plan development and it is expected to increase in many aspects. The aim of this study is to measure the performance of business plan in Digestive Endoscopy Center.Method: This study was conducted from April-December 2013 with quantitative method and cross sectional studies on 76 subjects and also used secondary data from endoscopy’s reports. The balanced scorecard contains 4 measurements, such as financial approach, customer approach, internal process approach, and learning and growth approach. Results: The financial approach resulted that income from 2 types of patients (cash and insurance) were increased in 2013. The customer approach resulted a high satisfaction rate with mean 4.69 of 5 for patient satisfaction and the employee satisfaction increased in 2013 (mean: 3.88 of 5) and in 2010 (mean: 3.64 of 5). Internal process approach was measured using facilities and infrastructure discovered is increased too. Learning and growth approach resulted that accumulation of trainings, achievement of target of the trainings was increased.Conclusion: The achievement of bussiness plan has been evaluated using balanced scored card and showed that there is a balance on the financial approach, customer approach, internal process approach, and learning and growth approach.Keywords: business plan, digestive endoscopy center, balance scorecard
Azithromycin and the Outcome of Treated COVID-19 Patients: A Hospital-Based Study
Authors: Usman Elly 
Published: August 2022

COVID-19 is an infectious disease that has been declared a pandemic. Currently, there is no validated pharmacological treatment for use in COVID-19 disease and is still in the clinical trial stage. The aim of this study to determine the association of azithromycin and the outcome of treated COVID-19 patients. This study used a retrospective cohort. The number of samples in this study were 40 subjects in each group of azithromycin and non-azithromycin. The research sample was all COVID-19 patients who were treated at Dr. M Djamil Hospital Padang with moderate and severe grades receiving treatment with azithromycin and non-azithromycin. The inclusion criteria in this study were moderate and severe COVID-19 patients and data related to research variables were complete and well-documented. Sampling technique with convenience sampling. Data analysis was performed using the Chi-square test. P < 0.05 was significant, and the data were analyzed using the SPSS version 21.0 program. The mortality of COVID-19 patients in patients receiving azithromycin therapy (80.0%) compared to non-azithromycin (85.0%). The results of the statistical test showed that there was no relationship of azithromycin administration with the outcome of COVID-19 patients (p>0.05), with OR (0.71, 95% CI 0.22-2.26). In this study, it is hoped that the decision on the use of azithromycin should consider the potential benefits and risks, evaluated that the possibility of the drug being effective is greater than the risk to the patient.
Literasi sikap kemandirian dalam berwirausaha melalui metode pembelajaran daring bagi mahasiswa peserta PMM prodi Pendidikan Sejarah UNIPMA
Authors: Soebijantoro S , Septianingrum Bela 
Published: August 2022

Penelitian ini dilakukan dengan tujuan untuk mengetahui bagaimana implementasi literasiÂ kemandirian dapat meningkatkan sikap kemandirian mahasiswa peserta Pertukaran Mahasiswa Merdeka (PMM) melalui metode daring pada pembelajaranÂ historiopreneurship di eraÂ pandemi Covid 19. Metode penelitian yang dipergunakan adalah metode deskriptif kualitatif yaitu berupa studi kasus. Sumber data diperoleh melalui wawancara, angket , studi arsip dan dokumen serta observasi langsung. Adapun pengumpulan data dilakukan melalui observasi, wawancara, dan studi dokumentasi. Observasi dilakukan dengan pengamatan langsung secara non partisipasi dalam berbagai kegiatan pembelajaran di kampus. Wawancara dilakukan baik secara terstruktur dengan daftar pertanyaan yang telah disistematisasikan berdasarkan gambaran awal yang didapat ataupun secara. Sedangkan data peningkatan sikap kemandirian dilakukan dengan menggunakan angket yang dianalisa melalui skala likert. Secara keseluruhan analisis data penelitian ini berpedoman pada langkah-langkah analisis data penelitian kualitatif dari Moleong (2011), yaitu: reduksi data, penyajian data, danÂ penarikan simpulan. Dari analisis data diperoleh hasil 1)Â Diperlukan literasi kesejarahan sebagai sebuah ilmu pengetahuan tentang masa lampau yang bermanfaat bagi manusia serta melakukan komersialisasi dengan jiwa dan semangat yang mampu menghadirkan produk-produk hasil kajian kesejarahan yang bisa diterima oleh masyarakat.2) Terdapat data peningkatan sikap kemandirian mahasiswa yaitu dengan 75,2 % responden mahasiswa PMM menunjukkan sikap sangat setuju bahwaÂ sikap kemandirian merupakan kunci keberanian seseorang untuk menekuni bidang kewirausahaan, 3) 81,3 % mahasiswa menyatakan bahwa di era transformasi digital, pariwisata sejarah merupakan bidang garapan lulusan prodi Pendidikan sejarah serta merupakan peluang bisnis yang sangat menjanjikan.
Situs mangiran Desa Sidorejo Kabupaten Madiun sebagai sumber belajar sejarah lokal
Authors: Lestari Anida Putri , Soebijantoro S 
Published: August 2022

Penelitian bertujuan untuk mengetahui potensi yang terdapat pada Situs Mangiran yang dapat dipergunakan sebagai sumber belajar sejarah lokal. Penelitian dilakukan di situs mangiran Desa Sidorejo Kecamatan Saradan Kabupaten Madiun. Metode yang dipergunakan adalah deskriptif kualitatif melalui observasi, wawancara dan studi dokumentasi. Observasi dilakukan secara non partisipasi dalam berbagai kegiatan masyarakat. Wawancara dilakukan secara terstruktur dengan daftar pertanyaan yang telah disistematisasikan berdasarkan gambaran awal yang di peroleh. Analisis data berpedoman pada reduksi data, penyajian data danÂ penarikan simpulan. Dari hasil analisa data ditemukan bahwa potensi situs mangiran sebagai sumber belajar sejarah lokal adalah Pertama, memberikan pemahaman kepada siswa bahwa situs tersebut semakin memperkuat fakta bersama situs lain yang diketemukan di wilayah Kabupaten Madiun tentang dinamika sosial ekonomi dan budaya masyarakatÂ yang mencerminkan corak budaya Majapahit, Kedua menambah dan memperluas pengetahuan siswa bahwa sejarah Madiun diwarnai sejumlah kekuatan politik yang silih berganti untuk menguasai wilayah Madiun sejak zaman klasik, mulai dari kekuatan politik yang bersifat lokal hingga kekuatan politik yang merupakan bagian dari kerajaan besar, seperti Singosari, Majapahit, Demak hingga Mataram Islam.
SALUD PERIODONTAL EN LOS PACIENTES QUE SUFRIERON COVID 19
Authors: Palma Chuque Grisselda del Rosario , Odiaga López Diana Carolina , Fernández Arrascue María Julia , Ojeda Gomez Roberto 
Published: August 2022

Al término del año 2019 en la ciudad de Wuhan en China, surgió el brote de un virus llamado SARS-CoV2 (COVID-19). Este virus es tan mortal que en pocos meses afecto alrededor de 180 países. Las personas infectadas por ese virus, presentan un Síndrome de dificultad respiratoria aguda o eventos trombóticos pulmonares y lo penoso es que aquellas que sobrevivieron ante esta situación, quedan con un alto porcentaje de secuelas pulmonares. Además, existen pacientes que están en un estado crítico por COVID-19, los cuales son más propensos a desarrollar lesiones periodontales, ulcerativas y también hiperpigmentación del paladar duro, tanto por los fármacos utilizados para su recuperación como también por la entubación del paciente y la disminución del microbiota, apareciendo nuevos patógenos que agraven las lesiones bucales.
Para la redacción de este artículo de revisión se utilizó el buscador académico Google Scholar y se seleccionaron 10 artículos como criterios de inclusión: estaban en español, publicados hace menos de 10 años y mostraban datos sobre enfermedades Periodontales. Los resultados indican que los medicamentos como los corticoides dañan la cavidad bucal.
Por eso es importante mencionar que aquellos pacientes que sufrieron de COVID 19, tuvieron una deficiencia en el aseo de sus dientes, dado que, por estar con oxígeno o con respirador artificial la limpieza oral no se realizaba cada 12 horas o al encontrarse inmovilizados esta tampoco se realizaba. Por otro lado, se debe recalcar que el uso excesivo de terapia farmacológica puede agravar las enfermedades bucales a través de mecanismos inmunes.
Fourth World Congress of Sports Physical Therapy Scientific Abstracts
Authors:   International Federation of Sports Physical Therapy,   International Journal of Sports Physical Therapy
Published: August 2022

The International Journal of Sports Physical Therapy is pleased to publish abstracts from the 4th World Congress of Sports Physical Therapy, which will take place in Nyborg, Denmark, August 26-27, 2022. The theme of the Congress is “Translating Science into Actioon.” The variety of presentations during this congress are examples of the contemporary sports physical therapy research activities taking place around the world. The abstracts presented in the following pages were selected by the Scientific Committee, which included members from and from the International Federation of Sports Physical Therapy. It should be noted that abstracts have not been reviewed by the Editorial Board, Associate Editors or Editor-in- Chief of the International Journal of Sports Physical Therapy. After careful review by an international team of reviewers, research abstracts will be presented by authors at the World Congress. Each abstract presents only a brief summary of a research project / presentation and does not permit full assessment of the scientific rigor with which the work was conducted. While the abstracts offer only preliminary results that may require further refinement and future validation, they do serve an important role of sharing new research ideas from around the world. This sharing of ideas helps to encourage worldwide dialogue among researchers, clinicians, and educators that will ultimately contribute to the sports physical therapy body of knowledge. Notice: The abstracts below are presented as prepared by the authors. The accuracy and content of each abstract remain the responsibility of the authors.
A Comparison of Pitching Biomechanics and Sport Specialization in High School Pitchers
Authors: Hamer Tyler J. , Rosen Adam B. , Wilkins Samuel J. , Nicholson Kristen F. , Bullock Garrett S. , Knarr Brian A. 
Published: August 2022

Background The prevalence of sport specialization in high school athletes continues to rise, particularly among baseball players. Previous research has focused on the incidence of injury among specialized and non-specialized athletes but has yet to examine the level of sport specialization and pitching biomechanics. Hypotheses/Purpose The purpose of this study was to investigate differences in pitching volume and biomechanics between low-, moderate-, and high-level specialized baseball pitchers. It was hypothesized that high-level specialized pitchers would have the most pitching volume within the current and previous years while low-level specialized pitchers would exhibit the least amount. The second hypothesis states that kinematics and kinetics commonly associated with performance and injury risk would differ between low-, moderate-, and high-level specialized pitchers. Study Design Case-Control Study Methods Thirty-six high school baseball pitchers completed a custom sport specialization questionnaire before participating in a three-dimensional pitching motion analysis. Sport specialization was based off current guidelines and categorized as low-, moderate-, and high-level specialized based upon self-reported outcomes. Pitchers then threw ≈10 fastballs from a mound engineered to professional specifications. Data averaged across fastballs was used for biomechanics variables. Key pitching biomechanical and pitching volume variables were compared between low-, moderate-, and high-level specialized pitchers. Results High-level specialized pitchers were older (p = 0.003), had larger body mass (p = 0.05) and BMI (p = 0.045), and threw faster (p = 0.01) compared to low-level specialized pitchers. Pitching volume and pitching biomechanics were similar across groups. Conclusions Pitching biomechanics were similar across groups, although high-level specialized pitchers threw with significantly higher throwing velocity compared to low-level pitchers. The low amount of pitching volume throughout the season may be responsible for the lack of additional observed differences. Further research should examine the relationship between pitching biomechanics, upper extremity strength and flexibility, and sport specialization. Level of Evidence Level III