bluuebunny/crossref_metadata_2025_split huggingface dataset:
MANEJO DE ANTIBIÓTICOS EN INFECCIONES INTRAABDOMINALES BAJO LA PERSPECTIVA DE LA RESISTENCIA A LOS ANTIMICROBIANOS EN EL SERVICIO DE CIRUGIA DEL HOSPITAL GENERAL DE LATACUNGA
Authors: Chicaiza Tayupanta Jesús Onorato , Chicaiza Quishpe Diana Cristina 
Published: December 2022

El desarrollo de la resitencia a los antimicrobianos en las infecciones intraabdominales requiere de un especial cuidado en la selección del esquema antibiótico para tartarlas. Objetivo: Nos proponemos revisar los esquemas de antibióticos primario y secudario utilizados en un servicio de cirugía bajo la perspectiva de la resistencia a los antimicrobianos. Materiales y metodos: se realizaron 165 cultivos en igual número de pacientes intervenidos quirurgicamente por infecciones intraabdominales en un Hospital de II nivel de atención de los cuales 134 desarrollaron especies de enterobacterias, 47 sensibles a los antimicrobianos y 87 resistentes en algun grado a antibioticos disponibles. Resultados: El esquema antibiótico primario incluyó los siguientes antibióticos: ceftriaxona/metronidazol 75,37%, Ampicilina/sulbactam 17,91%, ceftriaxona (sola), 2,99%, ciprofloxacina/metronidazol, 2,24% y ampicilina/metronidazol 1,49%. Las enterobacterias identificadas fueron en orden de frecuencia: fue E. coli (79%), K. neumonía (10%), P. aeruginosa (5%), P. vulgaris (4%), otras enterobacterias menos frecuentes fueron, C. freundi y E. cloacale.(2%), K. oxitoca, hafnia A, K. ozonea y S. marcenses menos de 2%. La resistencia de las Enterobactericeas: un 89,76% a la Ampicilina, 66,14% a la cefalotina y 66,20% a las sulfas. En cuanto a la E. coli los procentajes de resistencia fueron los siguientes: Ampicilina 89,62%, Cefalotina 62,26%; Mayor sensibilidad a: Aminoglucosidos 85,85%, Ciprofloxacina 66,04%, con porcentajes de sensibilidad bajos a las Cefalosporinas de tercera generación (63 a 67%). Al imipenem se mantine altos niveles de sensibilidad (97,71% y 99,6%). Se cambió en un 40% de casos a un nuevo esquema antibiótico que representó los siguientes porcentajes: Ceftriaxona/metronidazol en 20 pacientes (35,71%), seguido al esquema Piperacilina/tazobactam en 10 pacientes (17,86%), a Imipenem en 7 pacientes (12,5%) y en menores porcentajes a varios antimicrobianos identificados como efectivos en el tratamiento por los niveles de sensibilidad por las enterobacterias identificadas. La estancia hopitalaria estuvo en un promedio de 12,63 dias, las complicaciones se presentaron en 34% de los pacientes y la mortalidad global en 15,67%. Conclusiones:en hospitales de II nivel en el Ecuador el esquema antimicrobiano primario puede ser la combinación de ceftriaxona/meronidazol aunque en casos seleccionados podría asociarse un aminoglucosido/metronidazol. Es conveniente reservar esquemas antibióticos con carbapenémicos (imepenem) para casos con resistencia a los antimicrobianos del tipo PDR.
Pendampingan Hukum di Desa Selokang dalam mengoptimalisasikan Ekonomi Kreatif Berbasis Pariwisata
Authors: Wardani Sheila Kusuma 
Published: December 2022

Tujuan utama pelaksanaan kegiatan ini yaitu untuk memberikan pelatihan kepada masayrakat dalam mengoptimalisasi ekonomi kretaif di Desa Selokajang dengan memanfaatkan sektor Pariwisata. Program kerja dilakukan dalam rangka melakukan pemberdayaan UMKM di Desa Selokajang. Pada Masa pandemi Covid-19 diperlukan upaya lebih konkret agar produk UMKM tetap menunjukkan geliatnya. Pelaksanaan pengabdian ini dilakukan selama dua minggu dengan menggunakan media tatap muka secara langsung. Pelaksanaan kegiatan pengabdian kali ini dilakukan diantaranya (1) Membantu memasarkan produk UMKM; (2) Membuat design produk; (3) Membantu rebranding dengan pemasaran online di marketplace; (4) Membantu pengolahan produk susu etawa; (5) Membantu marketisasi produk melalui poster. Berdasarkan analisis hasil kegiatan maka dapat disimpulkan bahwa setelah kegiatan dilaksanakan terjadinya peningkatan omset, penyebarluasan akses produk UMKM serta kemampuan melakukan marketisasi produk UMKM menggunakan media sosial dan market place meningkat
PKM Pendaftaran PIRT dan Manajemen Promosi Produk Guna Peningkatan Pemasaran Industri Rumah Tangga Gula Merah di Desa Pasuruhan Kecamatan Mertoyudan Kabupaten Magelang
Authors: Dakum Dakum , Nuryani Tri , Khusna Atina , ‘Adnan Nasrulloh Akhmad , Aby Facturrohman Wimanda , Andri Ani Evi 
Published: December 2022

Industri Rumah Tangga di Desa Pasuruhan berkembang cukup baik, khususnya industri olahan gula merah. Walaupun, pemasaran yang dilakukan masih secara tradisional dan juga belum memiliki legalitas PIRT dari pemerintah. Kegiatan pengabdian ini bertujuan agar mitra dapat melakukan pendaftaran PIRT dan meningkatkan pemasaran produk. Metode yang digunakan adalah penyuluhan dan pendampinan kepada mitra secara langsung di lapangan (mitra terlibat aktif dalam kegiatan). Kegiatan ini dilakukan dengan melakukan persiapan, pelaksanaan inti, penyajian hasil pengabdian, dan pelaporan pengabdian. Hasil kegiatan pengabdian ini mitra mampu memahami terkait tata cara pendaftaran PIRT dan dapat melakukan pemasaran produk secara modern (online). Kegiatan serupa dengan ini sangat penting dilakukan di kemudian hari agar dapat membantu pelaku Industri Rumah Tangga dalam melakukan pendaftaran PIRT dan mampu melakukan pemasaran secara online.
SEBUAH STUDI KASUS KEBUTUHAN PSIKOSOSIAL DENGAN MASALAH KETIDAKBERDAYAAN PADA PASIEN PPOK
Authors: Yagi Jois Katrin , Agustine Uly , Boa Grasiana Florida 
Published: December 2022

Pendahuluan
: PPOK adalah gangguan pada paru-paru yang dapat menyebabkan sumbatan pada saluran pernapasan. Meningkatnya angka terjadinya penyakit ini sangat mempengaruhi psikososial penderitanya, hal ini disebabkan karena program pengobatan yang kompleks atau jangka panjang yang dapat menimbulkan masalah ketidakberdayaan. Peran perawat dalam memenuhi kebutuhan Psikososial pasien perlu diterapkan sehingga penulis berencana untuk melakukan pendekatan dengan melakukan proses keperawatan kepada Pasien PPOK dengan masalah keperawatan yaitu Ketidakberdayaan. Tujuan dilakukannya penelitian ini adalah untuk mendapatkan bagaimana gambaran mengenai tindakan proses keperawatan pada pasien jiwa dengan pasien PPOK dalam pemenuhan kebutuhan Psikososial dalam hal ini masalah Ketidakberdayaan. Metode pengumpulan data yang digunakan dalam melakukan studi kasus dengan jumlah responden 1 pasien adalah wawancara, observasi dan pemeriksaan fisik. Hasil: pengkajian yang didapat pada pasien Ny. R. usia 77 tahun mengatakan pasien merasa bosan saat dirawat di Rumah Sakit, dengan data objektif menunjukkan TD: 160/90 mmHg, N: 90x/menit, S: 36,6˚c dan RR: 24x/menit, pasien merasa putus asa, ADL pasien dibantu oleh keluarga, pasien tampak mengeluh dengan kondisi yang dialami, pasien terlihat gelisah dan menolak tindakan medis yang diberikan. Diagnosa yang ditegakkan adalah Ketidakberdayaan berhubungan dengan program perawatan/pengobatan yang kompleks atau jangka panjang. 3 hari dilakukan asuhan keperawatan hasil evaluasi yaitu ADL pasien dibantu oleh keluarga, pasien tampak tenang, pasien menerima tindakan medis yang diberikan, dan pasien ditemani oleh anak-anaknya. Kesimpulan: Setelah pasien mendapatkan tindakan keperawatan selama 3 hari, masalah ketidakberdayaan yang dialami pasien Ny. R sudah teratasi. Saran: asuhan keperawatan yang dilakukan di RS tidak hanya secara fisik namun harus secara holistik, dan juga melibatkan keluarga
Al-Ghazali's Concept of Happiness in The Alchemy of Happiness
Authors: Achmad Khudori Soleh  
Published: December 2022

Al-Ghazali's book entitled The Alchemy of Happiness describes happiness. It often becomes a reference of behavior of mysticism and psychology, especially Islamic psychology. However, there are no studies that specifically examine this book. This study analyzes al-Ghazali's concept of happiness in The Alchemy of Happiness. The research data sources consist of literature having The Alchemy of Happiness as their main references. The researcher uses the content analysis method to analyze the data. The research results show that (1) Al-Ghazali's concept of happiness refers to the Qur'an, Hadīths, Islamic philosophy, Sufism teachings, and al-Farabi’s leadership concept. (2) Al-Ghazali's principle of happiness is twofold: that happiness must be pursued and tiered. Al-Ghazali's concept of happiness consists of four aspects: appetence, reason, heart, and love for Allah. (3) Furthermore, the method of achieving happiness has three stages, (1) recognizing the nature and character of the self, (2) placing the heart as the leader of the self, and (3) contemplation of God. Al-Ghazali's concept of happiness has several advantages, namely use many Quarnic references; does not eliminate the potential for lust; and does not teach fatalism. In fact, he motivates people to pursue their happiness.
Keywords: Al-Ghazali, Alchemy of Happiness, Concept of happiness, aspects of happiness, Methods of achieving happiness
Islam and Nationalism in the Thought of Jamal Al-Din Al-Afghani
Authors: Azlan Ariff Aizuddin 
Published: December 2022

The dynamic of nationalism’s theoretical position has facilitated the unfolding complexities throughout history; and it still triggers an intellectual debate among the contemporary scholars. Carved out as a formidable socio-political force, nationalism today stands out as a substantial brand of resistance that defies all odds. This study has employed the qualitative method of analysis to build a framework to explore the ideas and thoughts of Jamal al-Din al-Afghani pertaining to the concepts of Islam and nationalism. Furthermore, this study argued that Afghani’s conception of Islam and nationalism was an effective tool in balancing the principles of modernity. In similar vein, Afghani’s core ideas and its underlying values suggested some different trajectories of fundamental synthesis of the nationalism and Islam. To elucidate further, Islam is viewed as a dominant force that perpetuated the development of Afghani’s comprehension on nationalism. This study culminates that Afghani’s concept of nationalism is the fundamental source of social unity that has consolidated the backbone of Islamic movement within the framework of Pan-Islamism by emphasizing the concept of unity and ummah.
Keywords: Jamal al-Din al-Afghani, Nationalism, Pan-Islamism, Social-unity, Western thought
IMPLEMENTASI STRATEGI PEMBELAJARAN DENGAN PENDEKATAN INDEX CARD MATCH DALAM MENINGKATKAN MOTIVASI BELAJAR SISWA DI MTS NEGERI 2 SLEMAN
Authors: Hasanah Nur Zaytun , Nurafni Nurafni 
Published: December 2022

In the some units of educational institutions, there are still use monotonous learning strategies, the teacher lecturing and students listening, it has an impact on students who are not enthusiastic to participating in the class. The index card match strategy is not implemented in all educational units, due to the lack of teachers in applying this method in classroom learning. In fact, with this method, it can overcome the problems that exist in the field related to the learning process.
The purpose of this study is to interpret the implementation of learning strategies with the index card match to increasing student motivation at MTS N 2 Sleman. This research is qualitative. Data collection techniques used are observation methods, documentation methods and interview methods. The data analysis technique used is Miles, Huberman and Saldana with the stages of data collection, data condensation, data presentation and drawing conclusions.
The results showed that the implementation of the learning strategy with the index card match approach was successful and successful in increasing students learning motivation at MTS N 2 Sleman. Therefore, with the index card match strategy, it will provide a new nuance for education, especially in the learning process. Learning with this strategy will make the learning atmosphere more fun and not boring.
Mesoporous crystalline Ti1-xSnxO2 (0 < x < 1) solid solution for a high-performance photocatalyst under visible light irradiation
Authors: Yu Wen , Geng Nankun , Han Jianming , Yu Wenjun , Peng Yiting 
Published: December 2022

We report a facile and effective inorganic polycondensation combined with aerosol-spray strategy towards high-performance photocatalyst by fabricating mesoporous Ti1-xSnxO2 (0 &lt; x &lt; 1) solid solution. Such Ti1-xSnxO2 nanocrystals with high Sn-doped contents are self-assembled into mesoporous spheres can effectively promote visible-light harvest and high quantum yield, leading a longer lifetime of the photoelectron-hole pairs and less recombination. Such the photocatalysts enhanced photocatalytic activity for the degradation of Rhodamine B (RhB). The representative Ti0.9Sn0.1O2 and Ti0.8Sn0.2O2 compounds reach an optimum degradation of ≈50% and 70%, respectively, after 120 min irradiation under visible irradiation. The mesoporous Ti1-xSnxO2 solid solution could inhibit the recombination of electron-hole pairs, which promote reaction thermodynamics and kinetics for RhB degradation.
Premature stroke and cardiovascular risk in primary Sjögren's syndrome
Authors: Zippel Clara L. , Beider Sonja , Kramer Emelie , Konen Franz F. , Seeliger Tabea , Skripuletz Thomas , Hirsch Stefanie , Jablonka Alexandra , Witte Torsten , Sonnenschein Kristina , Ernst Diana 
Published: December 2022

IntroductionPrimary Sjögren's syndrome (pSS) is associated with an increased prevalence of traditional risk factors and cardiovascular diseases (CVDs). The study aimed to identify specific risk factors for CVD in pSS patients.MethodsPSS patients with and without CVD were compared. All patients fulfilled the EULAR/ACR classification criteria. Patients with CVD presented at least one of the following manifestations: myocardial infarction, transient ischemic attacks, ischemic or hemorrhagic stroke, peripheral artery disease, coronary artery disease, and carotid plaques. Data were collected by a standardized protocol and review of medical records.Results61/312 (19.6%) pSS patients presented with CVD. Traditional risk factors such as hypertension, hypercholesterinemia and diabetes (p &lt; 0.05), pSS manifestations, in particular vasculitis (p = 0.033) and Raynaud's phenomenon (p = 0.018) were associated with CVD. Among patients with ischemic events (28/312, 9%), particularly cerebrovascular disease (n = 12/28, 42.9%), correlations with increased EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI) (p = 0.039) and EULAR Sjögren's Syndrome Patient Reported Index (ESSPRI) (p = 0.048) were observed. Age at first cerebrovascular event was 55.2 [48.9–69.6] years. Multivariate analysis confirmed hypertension [odds ratio (OR) 3.7, 95% confidence interval (CI) 1.87–7.18, p &lt; 0.001], hypercholesterinemia (OR 3.1, 95% CI 1.63–5.72, p &lt; 0.001), male gender (OR 0.4, 95% CI 0.17–0.78, p = 0.009), Raynaud's phenomenon (OR 2.5, 95% CI 1.28–4.82, p = 0.007), and CNS involvement (OR 2.7, 95% CI 1.00–7.15, p = 0.048) as independent CVD predictors.ConclusionRaynaud's phenomen as well as vasculitis and high ESSDAI have shown a significant association to CVD. PSS patients with cerebrovascular events were younger than expected. Knowledge about risk factors may help clinicians to identify pSS patients at risk for CVD. After diagnosis of pSS, patients should be screened for risk factors such as hypertension and receive appropriate therapy to prevent or at least reduce sequelae such as infarction. However, further investigations are necessary in order to achieve a reliable risk stratification for these patients.
Association between weight-adjusted-waist index and heart failure: Results from National Health and Nutrition Examination Survey 1999–2018
Authors: Zhang Daoliang , Shi Wenrui , Ding Zhaohui , Park Jieun , Wu Shaohui , Zhang Jian 
Published: December 2022

BackgroundWeight-adjusted waist circumference index (WWI) is a novel index positively associated with excessive fat accumulation. The current study aims to evaluate the association between WWI and the prevalent heart failure (HF), and to assess the value of WWI to improve the detection of HF in the general population.MethodsA total of 25,509 subjects from National Health and Nutrition Examination Survey 1999–2018 were included into our study. WWI was calculated as WC (cm) divided by the square root of weight (kg). HF was identified according to the subjects’ reports.ResultsThe prevalence of reported HF was 2.96%. With adjustment of demographic, anthropometric, laboratory, and medical history data, one SD increment of WWI could cast an additional 19.5% risk for prevalent HF. After separating WWI into quartiles, the fourth quartile had a 1.670 times risk of prevalent HF compared to the first quartile. Furthermore, smooth curve fitting suggested that the association was linear in the entire range of WWI. Moreover, the association was robust to subgroups of age, sex, race, obesity, hypertension, and diabetes. Additionally, ROC analysis revealed a significant improvement for the detection of prevalent HF from WWI (0.890 vs. 0.894, P &lt; 0.001); And continuous net reclassification index (0.225, P &lt; 0.001) and integrated discrimination index (0.004, P &lt; 0.001) also supported the improvement from WWI.ConclusionOur data demonstrated a significant, linear, and robust association between WWI, a simple surrogate for fat mass accumulation, and the risk for prevalent HF in a representative population. Moreover, our results also suggested the potential value of WWI to refine the detection of prevalent HF in the general population.
Association of alcohol consumption with abortion among ever-married reproductive age women in Ethiopia: A multilevel analysis
Authors: Ayana Galana Mamo , Raru Temam Beshir , Deressa Alemayehu , Regassa Lemma Demissie , Gamachu Mulugeta , Negash Belay , Birhanu Abdi , Merga Bedasa Taye 
Published: December 2022

BackgroundA miscarriage or a spontaneous loss of a pregnancy that occurs before the 20th week is an abortion. Even though numerous recommendations state that pregnant women should abstain from alcohol at all stages of pregnancy, alcohol intake among pregnant women is common. However, there are few papers addressing the effect of alcohol use on miscarriage using nationally representative data. Moreover, the association of alcohol use with abortion and its mechanisms is not well studied in the Ethiopian region. Therefore, the objective of the current study was to estimate the association of alcohol use with abortion rates among reproductive age (15–49) women in Ethiopia.MethodsUsing the most recent findings of the Ethiopian Demographic and Health Survey (EDHS), secondary data analysis was performed among pregnant women in Ethiopia. A total of 11,396 women between the ages of 15 and 49 years who were of reproductive age were included in the research. To characterize the study population, descriptive statistics were used. The variability was considered using the multilevel binary logistic regression model. A multilevel binary logistic model was used to determine the effect of alcohol intake on abortion while controlling for potential confounders. In the multivariable analysis, variables with a P-value of less than 0.05 were considered statistically significant for the response variable.ResultsThe proportion of women who had an abortion was 10.46% with a 95% CI of 9.92–11.03. In the ﬁnal model of the multilevel analysis, age group [adjusted odds ratio (AOR) = 6.13; 95% CI: 3.86–9.73], education level (AOR = 1.29; 95 and CI: 1.10–1.51), alcohol consumption (AOR = 1.38; 95% CI: 1.18–1.61), age at first sex (AOR = 1.20; 95% CI: 1.03–1.39), media exposure (AOR = 1.28, CI: 1.10–1.48), contraceptive use (AOR = 1.34, CI: 1.16–1.56), and occupation of respondent (AOR = 1.21, CI: 1.06–1.38) were identified to be significant determinants of abortion in Ethiopia.ConclusionSexual and reproductive health education and family planning programs should target older women in the reproductive age group, women with primary educational status, working women, and those who initiated sexual intercourse at a younger age considering it could reduce abortion and unintended pregnancy. Furthermore, as part of sexual and reproductive health education, the adverse effect of alcohol consumption on abortion should be emphasized.
Complement C3b contributes to Escherichia coli-induced platelet aggregation in human whole blood
Authors: Landsem Anne , Emblem Åse , Lau Corinna , Christiansen Dorte , Gerogianni Alexandra , Karlsen Bård Ove , Mollnes Tom Eirik , Nilsson Per H. , Brekke Ole-Lars 
Published: December 2022

IntroductionPlatelets have essential functions as first responders in the immune response to pathogens. Activation and aggregation of platelets in bacterial infections can lead to life-threatening conditions such as arterial thromboembolism or sepsis-associated coagulopathy.MethodsIn this study, we investigated the role of complement inEscherichia coli(E. coli)-induced platelet aggregation in human whole blood, using Multiplate®aggregometry, flow cytometry, and confocal microscopy.Results and DiscussionWe found that compstatin, which inhibits the cleavage of complement component C3 to its components C3a and C3b, reduced theE. coli-induced platelet aggregation by 42%-76% (p = 0.0417). This C3-dependent aggregation was not C3a-mediated as neither inhibition of C3a using a blocking antibody or a C3a receptor antagonist, nor the addition of purified C3a had any effects. In contrast, a C3b-blocking antibody significantly reduced theE. coli-induced platelet aggregation by 67% (p = 0.0133). We could not detect opsonized C3b on platelets, indicating that the effect of C3 was not dependent on C3b-fragment deposition on platelets. Indeed, inhibition of glycoprotein IIb/IIIa (GPIIb/IIIa) and complement receptor 1 (CR1) showed that these receptors were involved in platelet aggregation. Furthermore, aggregation was more pronounced in hirudin whole blood than in hirudin platelet-rich plasma, indicating thatE. coli-induced platelet aggregation involved other blood cells. In conclusion, theE. coli-induced platelet aggregation in human whole blood is partly C3b-dependent, and GPIIb/IIIa and CR1 are also involved in this process.