bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cryptocurrency Curated News Event Database From GDELT
Authors: Gadi Manoel Fernando Alonso , Sicilia Miguel Ángel 
Published: October 2022

Abstract
Event studies in general rely on having a high-quality curated database of events. In this paper we introduce CryptoGDelt2022, a news event dataset extracted from the Global Database of Events, Language and Tone (GDELT) containing more than 243 thousands cryptocurrency related news events between the 31st of March 2021 and 30th of April 2022. The dataset is enriched with supervised machine learning scores for Relevance, Sentiment and Strength. Supervised Relevance Score measures how related to Cryptocurrency the topic is using news web scrapped from Yahoo in general and from the Cryptocurrency part of the site, after a comparison of approaches; Latent Dirichlet Allocation (LDA), BERT and Naive Bayes, Naive Bayes was chosen and the hyper-parameter tuned model reached accuracy: 97.84 % in the train set and 91.70% in the test set. Supervised Sentiment Score measures the negative, neutral or positive tone of the news, after hyper-parameter tuning, the retrained FinBERT model achieved accuracy of 92.63% in the train set and 86.11% in the test set. Supervised Strength Score measures how strong the news by using the abnormal return using Fama French 3-factor model as target output variable, after hyper-parameter tuning, the trained Naive Bayes model reached accuracy of 63.34%. The work concludes that GDELT is more reliable source of event when compared to news selected from cryptocurrency specialized websites as it presents a more balanced positive and negative number of news. All data sets and Python Jupyter Notebooks are available in the project's GitHub.
Dieulafoy's disease of the bronchus: rare but potentially fatal
Authors: Daboussi Salsabil , Kacem Marwa , Boubaker Nouha , Chaabene Mariem , Aichaouia Chiraz , Mhamdi Samira , Moatemri Zied 
Published: October 2022

Abstract
Background: Dieulafoy’s disease of the bronchus can cause massive and even fatal hemoptysis. Even though it is rare, it should be considered by physicians all over the world, as several cases are reported by literature.
Methods and results: We report the case of a 41-year-old man, so far in good health, presenting with massive hemoptysis. Bronchoscopy showed blood clots and a protruding lesion covered by mucosa with a white pointed cap at the entrance of the right upper lobe. Biopsies were not attempted. Embolization of bronchial artery was first realized and was not successful, with post procedure complications. Surgical intervention stopped the bleeding and pathological examination of the resected specimen confirmed Dieulafoy’s disease of the bronchus.
Conclusion: To our knowledge, this is the first case of bronchial Dieulafoy’s disease to be reported in Tunisia and North Africa. When the diagnosis is suspected, bronchoscopy biopsy should be avoided as it might lead to fatal hemorrhage. Selective bronchial artery embolization can stop the bleeding, but surgery can be required.
Dynamics of absorption and evaporation of organic solvents in carbon nanotubes-embedded wood
Authors: Kim Do-Hyun , You Seungyeol , Lee Myeung-jin , Kim Hong-Dae , Kim Gyu Tae 
Published: October 2022

Abstract
Wood, a hygroscopic material, is sometimes exposed to organic solvents for decoration or protection. Compared with measuring water contents, it is still quantitively challenging to estimate the degree of the absorption and evaporation of organic solvents in wood. In this work, we investigated the dynamics of absorption and evaporation of various organic solvents in the wood by monitoring a change in an electric current. To realize this, we fabricated an electrically conductive wood by embedding multi-walled carbon nanotubes (MWCNTs) into the walnut timber. Then, organic solvents such as ethanol, n-hexane, acetone, toluene, benzene, and iso-propyl-alcohol were dropped in the MWCNTs-embedded wood under controlled voltage conditions. The current was changed differently during the absorption and evaporation of the solvents in the woods. As a result, we found that polar and nonpolar solvents exhibited different degrees of absorption and evaporation in walnut wood. Acetone and n-hexane are polar and nonpolar organic solvents absorbed and evaporated rapidly in the conductive wood among organic solvents. In addition, we found that the absorption and evaporation dynamics obeyed different mathematical models. Our work paves the way to study the absorption and evaporation of organic solvents in the frame of electrically conductive wood.
LG-MLFormer: Local and Global MLP for Image Captioning
Authors: jiang Zetao , Wang Xiuxian , Zhai Zhongyi , Cheng Bo 
Published: October 2022

Abstract
Self-attention-based image captioning model exists visual features’ spatial information loss problem, introducing relative position encoding can solve the problem to some extent. However, it will bring additional parameters and greater computational complexity. To solve the above problem, we propose a novel local-global MLFormer (LG-MLFormer) with specifically designed encoder module Local-global Multi-Layer Perceptron (LG-MLP). The LG-MLP can capture the latent correlations between different images and its linear stacking calculation mode can reduce computational complexity. It consists of two independent local MLP (LM) modules and a cross-domain global MLP (CDGM) module. The LM specially designs the mapping dimension between linear layers to realize the self-compensation of visual features’ spatial information without introducing relative position encoding. The CDGM module aggregates cross-domain potential correlations between grid-based features and region-based features to realize the complementary advantages of these global and local semantic associations. Experiments on the Karpathy test split and the online test server reveal that our approach provides superior or comparable performance to the state-of-the-art (SOTA). Trained models and code for reproducing the experiments are publicly available at: https://github.com/wxx1921/LGMLFormer-local-and-global-mlp-for-image-captioning.
Cancer associated fibroblast-dependent and -independent invasion of cancer cells
Authors: Kondo Ryotaro , Sakamoto Naoya , Harada Kenji , Hashimoto Hiroko , Morisue Ryo , Yanagihara Kazuyoshi , Kinoshita Takahiro , Kojima Motohiro , Ishii Genichiro 
Published: October 2022

Abstract
Purpose
Cancer cells are known to exhibit a cancer-associated fibroblast (CAF)-dependent invasive mode in the presence of CAFs. The purpose of this study was to investigate whether intrinsic factors of cancer cells influence the CAF-dependent invasive mode of cancer cells.
Methods
We observed the dynamic movement of CAFs and cancer cells by time-lapse imaging of 2-D and 3-D collagen invasion models and evaluated the invasion modes of gastric cancer cell lines (MKN-7, MKN-45, and HSC44PE). We further examined whether modification of the invasive capacity of CAFs can alter the invasive mode of MKN-7 and HSC44PE cells.
Results
When MKN-7 and MKN-45 were co-cultured with CAFs, CAFs first invade collagen matrix followed by cancer cells (CAF-dependent invasion), whereas HSC44PE invaded collagen matrix independently of CAFs invasion. Overexpression or suppression of podoplanin in CAFs, respectively increased or decreased the invasive capacity of CAFs themselves and significantly increased or decreased the number of invading MKN-7, respectively. CAFs overexpressing a podoplanin mutant lacking the cytoplasmic domain had a significantly reduced invasive capacity compared to CAFs overexpressing wild-type podoplanin, and it also reduced the number of invading MKN-7 cells significantly. When HSC44PE and CAFs were co-cultured, changes in the podoplanin expression in CAFs similarly altered the invasive capacity of CAFs themselves, but it did not affect the number of invading HSC44PE cells.
Conclusion
These results indicate that in the presence of CAFs, there are CAF-dependent and -independent modes of cancer cell invasion, the determinants of which may depend on the intrinsic properties of cancer cells.
Silicone oil as a corneal lubricant to reduce corneal edema and improve visualization during vitrectomy
Authors: Che Danyang , Chan Zhulin , Zhou Jibo , Zhu Dongqing 
Published: October 2022

Abstract
Purpose: To evaluate the efficacy and safety of silicone oil (SO) as a corneal lubricant to improve visualization during vitrectomy.
Design: A retrospective, interventional, observational study.
Methods: Patients who underwent vitreoretinal surgery were divided into two groups. Group 1 was operated on with initial SO as a corneal lubricant. Group 2 was operated on with initial lactated ringer’s solution(LRS) and then replaced with SO as required. Fundusclarity was scored during the surgery. Fluorescein staining was performed to determine the damage to corneal epithelium.
Results: 114 eyes of 114 patients were included. Single SO use maintained a clear cornea and provided excellent visualization of surgical image. In group 1, the fundus clarity was grade 3 in 41/45 eyes and grade 2 in 4/45 eyes. In group 2, corneal edema frequently occurred after initial LRS use. The fundus clarity was grade 3 in 19/69 eyes, 2 in 37/69 eyes and 1 in 13/69 eyes. This difference between two groups was statistically significant. SO was applied in 29 eyes of initial LRS use with subsequent corneal edema, which eliminated the corneal edema in 26 eyes. Corneal fluorescein staining score in group 1 was 0 in 28 eyes, 1 in 11 eyes and 2 in 6 eyes, and 40, 20 and 9, respectively, in group 2. This difference between two groups was not statistically significant.
Conclusion: The use of SO as a corneal lubricant is effective and safe for preserving and improving corneal clarity and providing clear surgical field during vitrectomy.
5 cases of mirror man combined with colorectal cancer treated surgically and literature review
Authors: Chen Xiao-Qiong , Chen Wei , Yang Lin-Qing , Chen Gui-Ting , Wang Xiao-Fang , Huang Yao-Yi , Huang Mei-Jin , Tan Shu-Yun 
Published: October 2022

Abstract
Background
Situs inversus totalis (SIT) is a rare congenital malformation in which the viscera is positioned in the opposite direction of normal, like a mirror. The patients of SIT with colorectal cancer (CRC) requiring surgical treatment are even more rare.
Methods
From January 2013 to May 2022, the clinical data of 5 SIT patients with CRC diagnosed in the Sixth Affiliated Hospital of Sun Yat-sen University were reviewed.
Results
Five SIT patients with CRCwere all female, aged 53-76 years. One patient died of complications after surgery due to poor cardiopulmonary function; One patient presented with a recurrent lesion of the side of the urethra after surgery and was readmitted for chemoradiotherapy. One patient died of tumor recurrence after surgery and chemotherapy. One patient with IIA was indicated by pathology after operation, and no recurrence was found. No tumor recurrence was found in one patient with early pathological indication. After reviewing 17 related literatures, together with 5 cases in our hospital, the most common primary sites of tumors were the sigmoid node and ascending colon, and the median survival of patients with combined chemotherapy was longer.
Conclusions
It is safe and feasible to perform surgery on the SIT patients with CRC after the preoperative examination and evaluation.
Association among epigenetic modifications by DNA methylation, telomere length, and physical fitness in biological aging
Authors: Seki Yasuhiro , Aczel Dora , Torma Ferenc , Jokai Matyas , Boros Anita , Suzuki Katsuhiko , Higuchi Mitsuru , Tanisawa Kumpei , Boldogh Istvan , Horvath Steve , Radak Zsolt 
Published: October 2022

Abstract
Cellular senescence is greatly accelerated by telomere shortening, and the steps forward in human aging is strongly influenced by environmental and life-style factors, whether DNA methylation (DNAm) is affected by exercise training, remains unclear. In the present study we investigated the relationships between physiological functions, maximal oxygen uptake (VO2max), vertical jump, working memory, telomere length (TL) assessed by RT-PCR, DNAmethylation based estimation of TL (DNAmTL) and DNA methylation based biomarkers of aging of master rowers (N = 151) and sedentary subjects (N = 90), aged between 37–85 years. It was found that the TL inversely correlated with chronological age, while no gender dependent difference was found. We could not detect association between telomere length and VO2max, vertical jump and working memory by RT-PCR method, while these physiological test results showed correlation with DNAmTL. DNAmGrimAge and DNAmPhenoAge acceleration were inversely associated with telomere length assessed by both methods. It appears that there is no powerful beneficial effects of exercise or physiological fitness on telomere shortening, however the degree of DNA methylation is associated with telomere length. DNAm based estimation of TL shows stronger relationships with physiological functions than RT-PCR measured data.
Fitting Concentric Elliptical Shapes Under General Model
Authors: Al-Sharadqah Ali , Piga Giuliano 
Published: October 2022

Abstract
The problem of fitting concentric ellipses is a vital problem in image processing, pattern recognition, and astronomy. Several methods have been developed but all address very special cases. In this paper, this problem has been investigated under a more general setting and two estimators for estimating the parameters have been proposed. Since both estimators are obtained iteratively fashion, several numerical schemes are investigated and the best initial guess is determined. Furthermore, the constraint Crame Rao lower bound for this problem is derived and it is compared with the variance of each estimator. Finally, our theory is assessed and validated by a series of numerical experiments.
Study on Rural Sewage Ecological Treatment System in China
Authors: WAN Ajun , Chen Hongling , Tu Runqiu , Qi Xiaolei , Wang Jiucheng 
Published: October 2022

Abstract
The rapid development of Chinese rural economy has led to an increasingly serious environmental pollution in rural areas, especially the random discharge of sewage to pollute water sources and endanger the health of villagers. This article combines the existing resources and needs in rural areas to study and establish a rural sewage ecological treatment system involving septic tanks, interception wells, improved integrated treatment equipment and waterlogging ponds, and takes Liutian Village in Shaanxi Province as an example. The system is based on the functional and practical principles from the rainwater and sewage collection system to drainage system, treatment system and recovery system. Ecological, economic and effective solutions are adopted in all aspects after comparative analysis. The input cost of the whole treatment system is relatively low, the effect is better and the functions are more. The sewage treated by this system meets the national emission standards. For rural sewage treatment, the system has good economic, social and ecological value and has broad application and promotion prospects.
WITHDRAWN: A PCA-EM hybrid model based on the spatial pattern of ecological vulnerability and correlation study
Authors: Wu Siqi , Kang Hou , Li Xuxiang 
Published: October 2022

Abstract
Ecological vulnerability reflects the ability of an ecosystem to resist adverse factors, and has become a global research hotspot. As an energy city in China and a city in the hinterland of the Loess Plateau, the study of Taiyuan's ecological vulnerability is of great importance. Most of the studies had used individual models, whose indicator weights were subject to large human factors or large compression of indicator information. In this study, an indicator evaluation system was developed based on the pressure state response (PSR). In order to overcome the shortcomings of a single model, a hybrid data processing model based on principal component analysis-entropy method (PCA-EM) was constructed in this study to study the ecological vulnerability of the area and compared with the principal component analysis model (PCA). Meanwhile, this study used Pearson correlation coefficients for analysis to evaluate the model performance and the influence of each parameter on ecological vulnerability. The research results illustrated that from 2000 to 2019, the EVI of Taiyuan showed a trend of first increasing and then gradually decreasing, indicating that it’s ecology was gradually improving. By comparing PCA method and PCA-EM method, the PCA-EM model could more objectively and reasonably evaluate the ecological environment of the region. Most of the indicators were negatively correlated with EVI, the highest correlation coefficient between per capita arable land and EVI. Furthermore, this study proposed a hybrid model to explore the ecological vulnerability status and influencing factors of the study area, providing an idea for data processing model.
Impact of WACC on Firm Profitability: Evidence from Food and Allied Industry of Bangladesh
Authors: Rahman Farhana 
Published: October 2022

Abstract
The research paper aims to analyze the underlying relationship in between the profitability and cost of funds of a firm. A total of twelve companies were selected as a sample for this study which are listed in Dhaka Stock Exchange under Food and Allied Industry. A panel data set of 15 years from 2005 to 2019 was used to conduct the necessary analysis. In this paper, Return on Asset (ROA) is used as the accounting criteria of profitability. WACC is the independent variable while Firm Size, Firm Age and Firm Leverage are used as control variable for the study. Fixed Effects Panel Regression Model is used to analyze the dataset. The result of the analysis shows that WACC is negatively related with the profitability measure and this relationship is significant. The study has potential to be replicated by other industries like textile, cement, pharmaceutical & chemical, fuel & power, tannery etc.
Research on the Impact of Face Threat and Perceived Sincerity on Online Shopping Service Recovery Satisfaction
Authors: Wei Jiahua , Li Lei 
Published: October 2022

Abstract
Online shopping has become a part of people's life, but the services failure has made online stores face huge challenges. It is urgent to explore the impact mechanism and strategies of its service recovery. Based on such psychological theories as face threat, perceived sincerity, consumer forgiveness and relationship strength, this study collected research data through scenario experiments and conducted empirical research. The results show that: Face threat and perceived sincerity have a negative and positive impact on consumer forgiveness, respectively; consumer forgiveness has a positive impact on service recovery satisfaction; relationship strength plays a positive moderating effect in the relationship between consumer forgiveness and service recovery satisfaction; consumer forgiveness plays a mediating effect between related variables. This study is conducive to analyzing the impact mechanism of online shopping service recovery from the perspective of consumer psychology, so as to provide theoretical basis and operational guidance for online stores to conduct scientific service recovery, improve online stores’ service recovery ability, and promote the healthy development of online shopping industry.
Comparative analysis of long-term precipitation trends and its implication in the Modjo catchment, central Ethiopia
Authors: Zena Besha Kokeb , Demissie Tamene Adugna , Feyessa Fekadu Fufa 
Published: October 2022

Abstract
Understanding trends and variability of precipitation is essential to improve water resources utilization as well as agricultural activities. This study aims to investigate the spatiotemporal trends and variability of rainfall in the Modjo watershed, central Ethiopia. The Mann-Kendall trend (M–K) test, innovative trend analysis (ITA) and Sen's slope estimator were used to determine temporal trends, while the inverse distance weighted interpolation technique was adopted to visualize the spatial trends in time series. The result showed that complex patterns of rainfall variability that range from 16 to 59%, 18 to 63%, and 50 to 90% for the annual, summer, and spring seasons, respectively was observed over the study watershed. The result also indicated that significant trend (p &lt; 0.05) in annual rainfall was detected only in 28.6% and 42.9% of the stations under the M-K test and ITA method, respectively, which indicates relatively more significant trends are displayed by the ITA method than the M–K test. At the seasonal scale, positive trends have been more dominant in the summer season (Z &gt; 0, SITA &gt; 0), whereas negative trends (Z &lt; 0, SITA &lt; 0) were detected in the spring season. Comparatively, the ITA method is found to be robust and allows more detailed trend analysis results using graphical illustrations for extreme events. The study concludes that the increasing and decreasing trends in summer and spring rainfall patterns could have implications leading to an increase in extreme events and lower agricultural productivity, respectively. The result suggests the need for planning effective adaptation strategies at the regional and local scales.
Influence of Quercetin Pretreatment on Pharmacokinetics of Warfarin in
Rats
Authors: Ahmad Ejaz , Jahangir Muhammad , Ismail Muhammad Akhter , Afzal Hafsa , Bano Shehar , Shamim Rahat , Bukhari Nadeem Irfan 
Published: October 2022

Background:
Warfarin (WAR) is an anticoagulant with a narrow therapeutic index and
is principally metabolized by CYP3A4 and CYP2C9 enzymes. The inhibitors of these enzymes
may alter the systemic exposure to WAR. Quercetin (QUE), a bioflavonoid, may modify the bioavailability
of drugs used concurrently by inhibiting CYP3A4, CYP2C8, CYP2C9, CYP1A2, and Pglycoprotein
(P-gp).

Objective:
The current study scrutinized the influence of QUE on WAR pharmacokinetics in rats.

Method:
QUE was orally administered to animals for 14 consecutive days, followed by WAR as a
single oral dose on the 15th day in the pre-treatment group. The co-administration group received a
single dose of QUE and WAR concomitantly. Only carboxymethylcellulose (CMC) 0.5% was administered
as a vehicle to control group.

Result:
In the pre-treated group, WAR’s Cmax was increased by 30.43%, AUC0-∞ by 62.94%, and t1/2 by
10.54%, while Cl decreased by 41.35%, relative to control. In co-administered animals, WAR’s Cmax increased
by 10.98%, AUC0-∞ by 20.20%, and t1/2 by 8.87%, while Cl declined by 16.40%.

Conclusion:
QUE alters the pharmacokinetics of WAR, warranting possibly WAR dose adjustment
after confirmatory clinical investigations, specifically in patients with thrombotic disorders
and a pre-treatment history of QUE or its product.