bluuebunny/crossref_metadata_2025_split huggingface dataset:
PRIMER REGISTRO DE ALBINISMO EN LA CULEBRA NARIZ DE PALA Conopsis nasus (Colubridae)
Authors: Berriozabal Islas Christian Said , Bautista Aurelio Ramírez , Tufiño José Daniel Lara , Jiménez Iris Aurora Nava , Picacho Roberto Arellano 
Published: April 2022

Conopsis nasus es una serpiente endémica a México, habita en bosques de pino-encino, matorrales xerófilos y submontanos, así como zonas perturbadas por la actividad humana. El 15 de enero de 2016, se encontró una hembra adulta de Conopsis nasus con coloración atípica albina, en la cabecera de Tula de Allende, Hidalgo, México. El ejemplar reportado se localizó en una zona de suelo calizo, lo que podría ayudar a explicar por qué logró alcanzar la talla adulta, a pesar de presentar una condición albina completa.
Asociación de factores sociodemográficos y académicos con aprendizaje autodirigido en estudiantes de medicina
Authors: García Franco Cristina , Márquez Celedonio Félix Guillermo , Gutiérrez Aguilar Pedro , Salazar Martínez Luis Lorenzo , Ramos Castro Rafael , Rosas Murga Flor Patricia 
Published: April 2022

Introducción: El aprendizaje autodirigido es una habilidad del estudiante que le permite obtener mayor desempeño académico a través de poner en práctica sus capacidades metacognitivas, motivacionales y conductuales, enfocadas en metas de adquisición de conocimientos y destrezas.Objetivo: Determinar la asociación del nivel de aprendizaje autodirigido con características sociodemográficas y académicas de estudiantes de medicina.Método: Se realizó una encuesta transversal comparativa en estudiantes de medicina, mediante la aplicación de la escala de autoevaluación del aprendizaje autodirigido y un cuestionario estructurado para recabar características sociodemográficas y académicas. También se efectuó un análisis con estadística descriptiva, pruebas de correlación, inferenciales y de asociación.Resultados: Se incluyeron en el estudio a 247 estudiantes de medicina con edad de 21.3 ± 1.9 años, 147 (51.4%) fueron de sexo femenino. La puntuación de aprendizaje autodirigido fue moderada en 116 (47.0%) estudiantes, y quienes tuvieron promedio superior a 9 alcanzaron puntuación de 120.1 ± 12.4 en comparación con 114.5 ± 12.5 de aquellos con promedio escolar de 8.00 a 8.99, y 110.7 ± 12.1 con los de 7.00 a 7.99 (p < 0 .001), r = 0.230. El promedio inferior a 7 obtuvo OR 2.3, IC 95% (1.01 - 5.27) para baja competencia de aprendizaje autodirigido. No hubo diferencia entre grados académicos (p > 0.05).Conclusiones: Estudiantes de medicina presentan desarrollo medio o semiestructurado de aprendizaje autodirigido, que se asoció con estatus académico y promedio escolar, pero no con características sociodemográficas ni grado académico.
Enseñanza de habilidades quirúrgicas: teorías educativas relevantes (segunda parte)
Authors: Gaxiola-García Miguel Ángel , Kushida-Contreras Beatriz Hatsue , Sánchez Mendiola Melchor 
Published: April 2022

Introducción: En el contexto de la educación médica, la educación quirúrgica es un área con características particulares. Múltiples conceptos, modelos y teorías se han desarrollado para caracterizar la educación quirúrgica; sin embargo, la mayoría se han reportado de forma aislada.Objetivo: Identificar los principales conceptos y teorías utilizados en educación quirúrgica para abordarlos de manera conjunta en un panorama integrador.Método: Como parte de una revisión panorámica de la literatura sobre educación quirúrgica se identificaron conceptos y sus potenciales relaciones. El análisis continuó de la siguiente forma: modelos no tradicionales para educación quirúrgica, estrategias tecnológicas para la educación quirúrgica como simulación, aprendizaje en línea y uso de redes sociales, así como el área de evaluación en educación quirúrgica, incluyendo habilidades técnicas y no técnicas.Resultados: En esta segunda parte del artículo, se describen alternativas al modelo tradicional de aprendiz de Osler y Halsted para la educación quirúrgica. El conocimiento e implementación de estos modelos descansa sobre bases teóricas probadas en algunos contextos. El uso de tecnología para la educación quirúrgica es más factible cuando esta es consistente con los modelos de aprendizaje, existe integración al diseño curricular, y se aprovechan las varias opciones disponibles. Existen múltiples herramientas que permiten conocer el grado de pericia psicomotriz del alumno como parte de una estrategia de evaluación formativa. Asimismo, la evaluación de habilidades no técnicas es un componente cada vez más importante de la educación quirúrgica.Conclusiones: Los gestores de programas de educación quirúrgica deben privilegiar un enfoque con sustento teórico en las etapas de planeación e implementación. Esto permitirá determinar objetivos y estrategias para su logro, en el contexto y formalidad de un programa estructurado y no solo calendarizado.
Práctica Basada en Evidencia en Adicciones: Conocimientos y Habilidades de Psicoterapeutas del Noroeste de México
Authors: Jiménez-Pérez Ana Lucía , Vargas-Contreras Eunice , Estrada-Vergara Norma Yadira , Arreola-Sánchez Ilse Abigail 
Published: April 2022

La Práctica Basada en Evidencia (PBE) es un proceso que inicia con el conocimiento de las evidencias disponibles y concluye con la selección de la mejor intervención para su implementación en escenarios clínicos lo cual impacta la efectividad de las intervenciones. Objetivo. Caracterizar el perfil de los terapeutas que laboran en 17 centros de tratamiento ambulatorio en adicciones del noroeste de México, además de sus conocimientos y habilidades en el uso de la PBE (fuentes de consulta, uso de manuales) y percepción de su autoeficacia. Método. Participaron 102 terapeutas, se contemplaron dos etapas: cuantitativa basada en la aplicación del CUTEA y cualitativa con aplicación de entrevista semi-estructurada, buscando contrastar las respuestas. Resultados. La mayoría de los participantes tuvo dificultad para describir el concepto de PBE, solo el 37.25% logró una adecuada definición sin embargo, reportaron altos niveles (95.91%) de autoeficacia para implementarla. En relación a las fuentes de consulta el 50% reportó utilizar cualquier buscador comercial en internet, mientras que el 46.08% referían usar los manuales de la institución. Al ingreso a su trabajo, no contaban con capacitación en adicciones ni en el área clínica. Discusión. Se aborda la necesidad del entrenamiento en la PBE y no solo en la implementación de tratamientos específicos.
The epidemiological profile of donors and non-donors of blood in Morocco
Authors: Jandou Issam , Kbirou Adil , Rachidi Hafida , Moataz Amine , Amaraoui Najia El , Benajiba Mohammed , Dakir Mohammed , Debbagh Adil , Aboutaieb Rachid , Hassoune Samira 
Published: April 2022

Introduction: In Morocco, blood donation is voluntary, anonymous, and voluntary. The promotion of blood donation has evolved favorably thanks to strategies based on the creation of a multi-sector promotion system. The transformation of family donors into voluntary donors and the retention of voluntary donors is the major challenge of the national blood transfusion center.
Materials and methods: This is an analytical quantitative cross-sectional study on a target population made up of 1000 participants. The collection tool was a self-administered, anonymous questionnaire made up of closed questions concerning the socio-demographic profile of the participants, and their knowledge and attitudes about the blood donation operation as well as their motivation and limitations of the donation. The responses were collected and entered by a team of graduate students in sociology. Data were analyzed by SPSS 20 software.
Results: Among the 953 participants, their mean age (Standard Deviation) is 32.56 (12.993) years, with 63.4% of the participants under the age of 34 (n = 429). For data relating to blood donation, 69.3% of the participants thought they did not know the blood group (n = 660), more than 70% thought of the existence of the illegal sale of blood in Morocco (n = 668). 69.3% of the participants think they do not know the blood type (n = 660), more than 70%, though of the existence of the illegal sale of blood in Morocco (n = 668), 70.8% do not know someone who has had or require an organ or tissue transplant (n = 479).
Conclusion: The need for blood is sharply increasing. an enormous shortage hence the need for epidemiological study to highlight the various difficulties that hamper the promotion of blood donation.
Keywords: Blood, transfusion, Blood donation, Promoting blood donation, Faithful donor, Morocco
Dendrimers and their applications
Authors: González Corrales Daniela , Fernández Rojas Nathalie , Solís Vindas Grettel , Santamaría Muñoz Maripaz , Chavarría Rojas Marianela , Matarrita Brenes Daniela , Rojas Salas María Fernanda , Madrigal Redondo German 
Published: April 2022

Dendrimers are symmetric molecules; their size is within the nanoscale. Its structure is usually homogeneous and monodisperse; they are composed of a nucleus and several layers 1. The number of layers that the dendrimer has defines its generation. There are different types of dendrimers. The synthesis of these macromolecules is carried out following steps of growth and activation, and organic reactions are required to obtain their branched structure2. Although size is essential, the determining factor of toxicity in dendrimers is the charge of the surface; it has been found that the higher generation dendrimers and the cationic ones are the most toxic compared to the lower generation anionics that evaluated at low concentrations did not show any toxicity 3. The dendrimers will favor the pharmacokinetics of a drug through the dendritic structure, the generation of the dendrimer to be used, the intramolecular interaction force between the adjacent functional groups in the dendrimer, the conditions of the environment such as pH, solvent polarity, strength ionic, saline concentration or presence of counterions, among others 4. Due to dendrimers' size and surface composition, the use of dendrimers in drug delivery has been increasingly studied. There are different interaction mechanisms between drugs in dendrimers, and these can be broadly divided into simple encapsulation, electrostatic interaction, and covalent bonds 5. The use of dendrimers in ocular administration has greatly impacted the complexity of this administration route. Gene therapy has also benefited from the emergence of these molecules as it facilitates targeted therapy.
Keywords: Dendrimers, Drug delivery, Gene therapy, Pharmacokinetic, Transport System
Ki-67 Expression Level in placentas with COVID-19 Infected Women
Authors: Kıratlı Sevil , Aktaş Ayfer , Aşır Fırat , Ermiş Işılay Sezen , Deveci Engin 
Published: April 2022

Objective: The SARS-CoV-2 virus, which emerged in December 2019 in Wuhan, China, spread very quickly in a short time and was declared a pandemic by the World Health Organization in March 2020. Physiological and immunological changes during pregnancy cause complications in respiratory tract infections. Complications by COVID-19 lead to a systemic effect that causes maternal and fetal mortality and morbidity. In this study, we aimed to investigate histopathological changes and Ki-67 expression in placentas of women with positive COVID-19 infection.
Study Design: Placentas of 10 samples COVID-19 positive and 10 samples Covid-19 negative pregnant patients who were hospitalized in the Gynecology and Obstetrics Clinic of Dicle University Faculty of Medicine were included in the study. Placental tissues were fixed in 10% formaldehyde (24 hours) and processed for routine paraffin wax tissue staining. Hematoxylin Eosin dye and Ki-67 immunohistochemical staining were performed.
Results: Decidual cell degeneration, increased numbers of syncytial nodes, dilatation in vessels, degenerated villi were observed in the placentas of COVID-19 positive pregnant women. COVID-19 damage regular histology of placental structures. Ki-67 expression was intensely increased in COVID-19 positive placentas compared to COVID-19 negative placentas.
Conclusion: We suggest that COVID-19 causes some abnormalities in the histology of placentas and cell death, which leads to new cell proliferation.
Keywords: COVID-19, placenta, villi, Ki-67, histopathology
Minocycline abrogates lung oxidative damage and haematological perturbations in mice exposed to hypoxia
Authors: Eduviere Anthony , Otomewo Lily 
Published: April 2022

Objectives: Hypoxia results from the unavailability of sufficient oxygen to tissues. Since previous studies have shown that hypoxia results in inflammation, this research has found it necessary to investigate the impact of chronic hypoxia on the lungs and blood of mice and also the potential benefit of minocycline which is a well-known antibiotic.
Design: Thirty mice were split into 5 groups of 6 animals each. A physical model of hypoxia was used. Here, mice were locked in a 250 mL airtight container for 20 mins each day for seven consecutive days.
Interventions: One hour before exposure to hypoxia, mice in all groups except the vehicle group, were treated with varying doses of minocycline (10, 20, 40 mg/kg, p.o.).
Main Outcome Measures: The mice in the positive control group expressed a sign of lung inflammation with an increase in myeloperoxidase activity, as well as lung oxidative stress with an increase of prooxidants over antioxidants. While in the blood, white blood cells were significantly increased whereas red blood cell count depreciated as blood volume did too.
Results: The various effects of hypoxia on the blood and lungs of the mice were significantly prevented and attenuated to an acceptable degree by minocycline
Conclusion: In conclusion, minocycline expresses an acceptable benefit in the respiratory and circulatory systems of mice in hypoxic conditions.
Keywords: Hypoxia, Lungs, Blood, Haematology, Oxidative stress, Minocycline
A Brief History of the Development and Liquidation of the Permanent System of Medical and Technical Tests and Medical Research at the Rzhevka Landfill оr 80 years in the ranks. (1928–2008)
Authors: Bobrus V. V. , Dmitrochenko I. V. , Matveev S. A. 
Published: April 2022

Based on open documentary and information sources, the authors of the article show the historical stages of creation, formation, and work in the structure of the Rzhevka research and testing artillery range of a specialized medical unit responsible for the quality and compliance of prototype weapons with the basic ergonomic requirements set out in the tactical and technical specifications for their development. Such a unit was created in 1928 on the initiative of the People’s Commissar of Defense M. N. Tukhachevsky. For 80 years of its interaction with the test site, up to 2008, it made a significant contribution to increasing the combat power of the domestic land and naval artillery. Despite the wide range of experimental studies and the large volume of tasks facing this unit, its employees have always been distinguished by the highest level of professionalism, innate military intelligence, and exemplary responsibility for the execution of the task assigned to them. For such an approach to the profession, the test site testers have always treated colleagues in medical uniforms with great respect. This article tells, about who these people were, what they did for their native country, what universal and moral principles they were guided by.
AKTIVITAS ANTIBAKTERI MINYAK SERAI DAPUR dan MINYAK ADAS pada Staphylococcus aureus di RUANG INAP RUMAH SAKIT
Authors: Nisyak Khoirun , Hartiningsih Susi 
Published: April 2022

ABSTRACT
Pathogenic microbial contamination is one of the causes of nosocomial infection in hospitals. Lemongrass oil and fennel oil are essential oils that are used as antimicrobials especially against Staphylococcus aureus. The purpose of this study was to determine the antibacterial activity of lemongrass oil and fennel oil against S. aureus isolated from Anwar Medika Sidoarjo hospital ward through the air diffusion method using essential oil diffuser. The compounds in lemongrass oil and fennel oil were analyzed by Gas Chromatography-Mass Spectrometer. The antibacterial activity test was conducted by the air capture method and continued with the Gram staining, catalase test, coagulase test, and calculation of the number of colonies. The results obtained from this study showed a decrease in the number of S. aureus colonies after the use of essential oils for 48 hours. Based on these results it can be concluded that lemongrass oil and fennel oil can suppress the growth of S. aureus bacteria isolated from hospital wards.
Keywords: antibacterial, lemongrass oil, fennel oil, S. aureus, hospital
ABSTRAK
Kontaminasi mikroba patogen adalah salah satu penyebab terjadinya infeksi nosokomial di rumah sakit. Minyak serai dapur dan minyak adas merupakan minyak atsiri yang dapat dimanfaatkan sebagai antimikroba khususnya pada bakteri Staphylococcus aureus. Tujuan penelitian ini untuk mengetahui aktivitas antibakteri minyak serai dapur dan minyak adas terhadap S. aureus di ruang rawat inap rumah sakit melalui metode difusi udara dengan menggunakan Diffuser Essensial Oil. Kandungan senyawa dalam minyak sereh dapur dan adas dianalisa dengan GC-MS. Analisa aktivitas antibakteri menggunakan metode tangkap udara dan dilanjutkan uji perhitungan jumlah koloni, pewarnaan Gram, uji katalase, dan uji koagulase. Hasil yang diperoleh dari penelitian ini menunjukkan penurunan jumlah koloni S. aureus setelah penggunaan minyak atsiri dalam jangka waktu 48 jam. Berdasarkan hasil tersebut dapat disimpulkan bahwa minyak serai dapur dan minyak adas memiliki kemampuan untuk menekan pertumbuhan bakteri S. aureus dalam ruang perawatan inap rumah sakit kelas III.
Kata kunci: antibakteri, minyak serai dapur, minyak adas, S.aureus, rumah sakit
Entre cañaduzales Mudarra
Authors: Vargas G. Bibiana 
Published: April 2022

Reflexionar sobre los modos de producción en el área de lo territorial, implica dar cuenta de la apropiación y pertenencia a un espacio que enmarca actividades productivas, materiales y simbólicas, así como de relaciones de poder y de sentido desde lo vivencial y lo institucional que convergen en un mismo lugar, como la vereda Mudara en el municipio de Supía, en el departamento de Caldas - Colombia. El propósito de este artículo es evidenciar las dinámicas socioproductivas alrededor de la producción de la caña panelera que generan procesos de cambio y continuidad. El método etnográfico permitió desde el trabajo in situ, el análisis de las narrativas y prácticas tanto cotidianas como institucionales. Los resultados dan cuenta de diferentes modos de producción alrededor del sistema productivo de la caña panelera: el tradicional, el comunitario y el empresarial, y estos, por un lado, muestran que persiste un modo de producción tradicional-familiar y, por otro, la existencia de estrategias de producción emergentes que contribuyen al desarrollo local de las comunidades campesinas; aspectos que inciden en la configuración productiva y social de los territorios rurales.
Effect of Dentin Moisture in Posterior Restorations Performed with Universal Adhesive: A Randomized Clinical Trial
Authors: Castro AS , Maran BM , Gutierrez MF , Chemin K , Mendez-Bauer ML , Bermúdez JP , Reis A , Loguercio AD 
Published: April 2022

SUMMARYObjectivesThis double-blind, randomized clinical trial evaluated the influence of dentin moisture on postoperative sensitivity (POS), as well as, on clinical performance in posterior bulk-fill composite restorations, using a universal adhesive, until 12 months after clinical service.Methods and MaterialsIn accordance with a split-mouth design, 45 patients received posterior restorations, restored with a bulk-fill resin composite (Filtek Bulk Fill, 3M Oral Care) and a universal adhesive used in etch-and-rinse mode (SBU; Single Bond Universal Adhesive), which were applied on dry or moist dentin, with a cavity depth of at least 3 mm. Three operators placed 90 Class I/Class II restorations. Patients were evaluated for spontaneous and stimulated POS in the baseline, and after 48 hours, 7 days, and at 6 and 12 months. In addition, secondary parameters (marginal discoloration, marginal adaptation, fracture, and recurrent caries) were evaluated by World Dental Federation (FDI) criteria after 7 days and at 6 and 12 months. Statistical analyzes were performed using the Chi-square, Fisher exact, Friedman, Kruskall–Wallis, and Mann–Whitney tests (α=0.05).ResultsNo significant spontaneous and stimulated POS was observed when SBU was applied in dry and moist dentin (p&gt;0.05). A significant and higher risk of spontaneous POS (20.0%; 95%CI 10.9–33.82 for dry dentin and 22.22%; 95%CI 12.54–36.27 for moist dentin) occurred up to 48 hours after restoration placement for the dry and moist dentin groups (p&lt;0.02). However, the POS intensity was mild up to 48 hours with no significant difference between dry and moist dentin groups (p&gt;0.79). When secondary parameters were evaluated, no significant differences between the groups were observed.ConclusionDentin moisture did not influence POS in posterior bulk-fill composite restorations when associated with a universal adhesive applied in etch-and-rinse mode.
Currículo y crisis epistemológica cultural
Authors: Sánchez Janina Moquillaza , Gutiérrez María Flores , Huamaní Oscar Gutiérrez 
Published: April 2022

El objetivo del artículo es analizar por medio de reflexión cualitativa hermenéutica cultural, las bases para la formación de profesores, frente a la epistemología cultural racionalista, eurocéntrica, en uso en estudios e investigaciones en la educación en el Perú. Nuestro objeto de reflexión, el Proyecto Educativo Nacional, al 2036. El problema: se mantiene paradigma excluyente en el currículo nacional, la alienación a realidades del cotidiano contemporáneo, en la relación escuela-sociedad y la filosofía ancestral andina, el principio del Allin Kawsay, generando conflictos didáctico pedagógicos, fragmentaciones, tensiones éticas, antropológicas, sociológicas y de identidades. Preguntamos: ¿El Proyecto posibilita percibir la larga crisis vigente? ¿Reconoce la necesidad de cambio epistemológico cultural? Recurrimos a teorías de Bachelard, Jung, Durand, Giroux, Morin y, nuestra propia experiencia de docentes e investigadores. Resultados encontrados: la educación se mantiene ajena a la concientización de responsabilidades y elecciones colectivas en la historia de vida escolar cotidiana. Finalizando, como el Ministerio de Educación desea formar nuevos educadores-investigadores, proponemos la ciencia cualitativa holística y el Allin Kawsay.
Phase Field Modeling of Ghost Diffusion in Sn-Ag-Cu Solder Joints
Authors: Weerasekera Naveen , Cao Siyua , Shingdon Dawa Ram 
Published: April 2022

In this paper, we have introduced a phase field modeling technique to simulate ghost diffusion phenomena of intermetallic compounds in a bulk mettalic matrix phase. We used Zenner-Frank phase field approach to define free energy density functional which is to be evolved using Chan-Hilliard and Alan-Chan equations to simulate time evolution of the precipitates. We verified our simulation results with intermetallic compound growth of Sn-Ag-Cu solder joints in isothermal aging process attributing to the diffusion of Ag3Sn intermetallic compound. Herewith we present that Zenner-Frank model demonstrates sound validity and provides a best understanding of such phenomena.