bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lessons from Polio Eradication: A synthesis of implementation strategies for global health services delivery from a scoping review
Authors: Neel Abigail H. , Olateju Adetoun , Peters Michael A. , Schleiff Meike , Alonge Olakunle 
Published: August 2022

Abstract
Introduction: There is limited guidance on strategies for delivering complex global health programs. We synthesized available evidence on implementation strategies and outcomes utilized in the global polio eradication initiative (GPEI) across low and middle-income country (LMIC) settings. Methods: We nested our scoping review into a literature review conducted as part of a parent study, STRIPE. This review systematically searched PubMed for articles between 1 January 1988 and 25 April 2018 using polio search terms. Strategies from included studies were organized according to the Expert Recommendations for Implementing Change (ERIC) framework, specified using Proctor’s framework, and linked to various outcomes (implementation, services delivery, impact).Results: 152 unique articles fulfilled our inclusion criteria (from 1,885 articles included in the parent study). Only 43 out of the 152 articles described a suitable quantitative study design for evaluating outcomes. We extracted 66 outcomes from the 43 unique studies. Study publication dates ranged from 1989-2018 and represented diverse country settings. The most common implementation strategies were developing mechanisms for feedback, monitoring, and evaluation (n=69); increasing awareness among the population (n=58); involving stakeholders, workers, and consumers in the implementation efforts (n=46); conducting workshops (n=33); using mass media (n=31); and building robust record systems to capture outcomes (n=31). Coverage (n=13) and morbidity (n=12) were the most frequently identified outcomes, followed by effectiveness (n=9) and fidelity (n=6). Coverage of polio vaccination was the most common implementation outcome, followed by acceptability and fidelity. Feasibility and sustainability were rarely evaluated.Conclusions: This review provides a catalogue of implementation strategies and outcomes relevant for advancing global health services delivery in LMICs drawing from the GPEI. Implementation strategies reviewed were poorly described and not adequately linked to outcomes. It calls for additional implementation research to unravel the mechanisms of implementation strategies and their effectiveness, and adaptation of the ERIC framework in LMICs. Systematic Review Registration: N/A
Association between Social Network, Social Support, and Life Satisfaction Among Elderly in India: Evidence from LASI Survey
Authors: Mandi Raghunath , Bansod Dhananjay W 
Published: August 2022

Abstract
BackgroundLife satisfaction is an indicator of subjective wellbeing among the elderly and is directly associated with health status, family structure, social support, amount of their social interaction, and the surrounding social environment in which the elderly live and interact. This study aims to investigate the association between family and social relations and life satisfaction among elderly aged 60 and above in India.MethodsUsing the first wave of the Longitudinal Ageing Study in India (2017-18) we had tried to assess how family and social relations contribute to life satisfaction among elderly aged 60 and above using the SWLS scale. Chi-square and ordered logistic regression were used in investigating the association between life satisfaction and varying aspects of family and social relations.ResultsOur result shows that, 45% of the study participants had higher life satisfaction, 22% had medium life satisfaction and 32% reported low life satisfaction. Our results highlight social participation, building social relationships, having close relationships with spouse/partner, receiving social support, and feeling of safety at home and neighborhood environment are strongly associated with life satisfaction among the elderly. Apart from family and social environment respondent’s socio-demographic structure also contributes to life satisfaction, especially at older ages.ConclusionsOur study recognizes that family and social relationships are important domains to promote well-being among the elderly. With rapidly soaring elderly population in India, the policy interventions should focus primarily on family and community to enhance wellbeing and to achieve successful ageing in the near future.
Metabolomic and transcriptomic profiling of DRG reveal a common pattern of changes in early sciatic nerve injury male rats neuropathic pain
Authors: Xu Zhenzhen , Feng Yi-Qi , Wang Yan-Ting , Li Xia , Liu Jie , Xiong Yue , He Yu-Yao , Chen Lu , Liu Guo-Yang , Xie Wan-Li , Wu Qingping 
Published: August 2022

Abstract
Objective: Neuropathic Pain (NP) is a clinically common chronic refractory pain syndrome which threat to approximately 7–10% of the global population physical and mental health. However, the mechanism of metabolism alteration in NP remains unclear. This study is intended to figure out the relationship between the alternation of metabolism and the progression of NP. Methods: In this study, metabolites of dorsal root ganglion (DRG) in sciatic nerve injury (SNI) rats and Sham rats were detected using liquid chromatography mass spectrometer (LC‐MS). Transcriptomic data were obtained from Beijing Genomics institution (BGI) which used to detect transcriptomic genes. Kyoto Encyclopedia of Genes and Genomes (KEGG) database was performed to enrich the pathways. Joint-pathway combined analysis performed on Metaboanalyst.ca. Results: A total of 199 metabolites have been identified and measured, of which 6 compounds exhibited the differential expression between SNI group and Sham group. Metabolites set enrichment analysis (MSEA) displayed that there were 5 significantly enriched pathways in all. Through the KEGG database, downregulated 26 genes were found closely correlated with the altered metabolic pathways. BGI transcriptomic profiling revealed that 274 genes significantly changed between SNI group and Sham group. Integrating these genes with the transcriptomic data from the corresponding KEGG data set, we identified most of the differential expressed genes were related to amino acid metabolism, especially β-alanine acid metabolism. A total of 21 different expression genes were hub integrating genes, where in gene C0099 expression of β-alanine and ALDH was significantly effective in the prediction of therapeutic target of NP. Conclusions: Combining with the transcriptomic and metabolomics data, we found that the dysregulation of amino acid metabolism pathway β-alanine accumulation might affect the progression of NP.
Suckling hierarchy and performance of piglets in the farrowing phase with artificial ventilation and roof sprinkles
Authors: Vaz Gisele Dela Ricci , Titto Cristiane Gonçalves 
Published: August 2022

Abstract
The hierarchy between pigs occurs in the first days after birth and can be influenced by the sequence in which piglets breastfeed on teats. This study aimed to evaluate whether the artificial ventilation and roof sprinklers causes hierarchical changes in feeding and weight gain of piglets. The study was conducted at a farrowing unit with 26 individual stalls, half of them with fans and roof sprinklers. Twenty-six females and 281 piglets, of second birth order, with weaning at 21 days were evaluated. The piglets were numbered and distributed in weight categories. The teats were delimited on the left and right sides, forming classes. The recording of the teats where the piglets breastfed and the disputes were carried out from the second day of birth to weaning, three times a week, in two daily evaluations. The imposition of the hierarchy was attributed to the registration of agonistic behaviors among the piglets, identifying the sender, receiver, the type of behavior performed by the aggressor and the counter-reaction of the victim. Higher means of seeking teats were found in the intermediate, upper and lower classifications, with no statistical difference between environments and periods of the day. In the establishment of the hierarchy, no strictly dominant, intermediate or subordinate animal was found. Piglets classified as heavier at birth were heavier at weaning in both environments evaluated. It was concluded that the sequence of piglets in the mammary gland influences the weight gain of pigs at the end of the farrowing phase.
Comparative study of Au, Al, and Ag metal based SPR sensor using nickel and antimonene to enhance the sensitivity in visible range
Authors: Pandey Sushant , Singh Sachin , Lohia Pooja , Yadav Rajesh Kumar , Dwivedi D.K. 
Published: August 2022

Abstract
In this simulation work, comparative study of surface plasmon resonance (SPR) based sensor designed with gold (Au), Aluminium (Al), Silver (Ag) are numerically investigated to improve the performance parameter of device using Ni-Antimonene layer in the visible range of light at wavelength of 633nm. In this device configuration, different metals (Ag/Au/Al), a diamagnetic material (Fe2O3), Nickel (Ni) and 2D material Antimonene (Sb) is used with CaF2 glass prism using Kretschmann configuration with angle interrogation method. The angle interrogation method is used to examine the performance of the device. The performance parameters of SPR sensor such as sensitivity, detection accuracy (DA), quality factor (QF) has been calculated. The thickness of metals (Au/Al/Ag) and number of different material thickness has been optimized by using genetic algorithms to improve the performance of device. The present study reveals that Ag metal based SPR Sensor exhibit a higher sensitivity as compared to Al and Au based SPR sensor at 55 nm of thickness. At 55nm thickness of Ag minimum reflectance curve has been obtained in comparison with Au and Al. The studied multilayer configuration of SPR sensor device using different metal Au/Al/Ag with Fe2O3, Ni and Antimonene in presence of glass prism, the maximum sensitivity 3100/RIU is obtained in case of Ag. The sensitivities of Au and Al metals are 660RIU-1, 2040RIU-1 respectively which is less in comparison to Ag metal. The different performance parameter of SPR sensor such as sensitivity, full width at half maximum (FWHM) value, DA, figure of merit (FoM), limit of detection (LoD) is calculated for all three metals but in the case of Ag performance is good compared to Au and Al. The penetration depth (PD) 110.5nm and 3D plot of transverse electric (TM) field intensity have also been plotted. The proposed SPR sensor using Ag metal with highest sensitivity value has capability to detect the different liquid analytes in the field of biosensing application with large uses in biomedical field in visible range.
Macroeconomic determinants of balance of payments performance in selected African countries
Authors: Abille Adamu Braimah , Meçik Oytun 
Published: August 2022

Abstract
Most African countries are open and are still opening up for international trade such that they are signatories to various trade agreements such as the Economic Partnership Agreement (EPA) with the EU, and Forum on China-Africa Cooperation (FOCAC), among others. However, these countries face a common persistent balance of payment deficit challenges, but the existing literature investigates this problem at specific country levels. Meanwhile, African countries are also rapidly transitioning towards economic integration with the establishment of the African Continental Free Trade Area (AFCFTA) to deepen intra-Africa trade. Therefore, for unionized policy proposition purposes, this study seeks to investigate the determinants of the balance of payments performance of African countries as a group based on panel data from 1990 to 2020 for 33 of these countries. For robustness checks, the system-GMM, the Random, and Fixed effects models are employed for estimating the determinants of BOP chosen based chiefly on the MABOP theory. The results show that domestic income, trade openness, and the broad money supply are the critical determinants of BOP performance in Africa. Further, the findings do not confirm the domestic income growth-BOP performance trade-off hypothesis, and an inverted U-shape rather than J-curve phenomenon is observed for Africa relative to the exchange rate. Based on the findings, the study recommends inter-alia that, African countries pursue value-creation-oriented investment, import substitution industrialization, as well as zero central bank budgetary financing policies to improve their BOP performances.
Multidisciplinary ocular and periocular cancers meetings: implementation in a tertiary referral center and analysis over a 12-months period
Authors: Savino Gustavo , Piccinni Fabrizio , Pagliara Monica Maria , Sammarco Maria Grazia , Caputo Carmela Grazia , Moro Alessandro , Barbera Giorgio , Tagliaferri Luca , Fionda Bruno , Schinzari Giovanni , Rossi Ernesto , Zagaria Luca , Peris Ketty , Stefani Alessandro Di , Musarra Teresa , Cefaro Luca Ausili , Martucci Matia , Blasi Maria Antonietta 
Published: August 2022

Abstract
Purpose The complexity of multimodal approaches in cancer management has lately led to the establishment of multidisciplinary tumor boards (MDTBs) to define targeted, patient-centered treatment strategies. However, few data are available regarding the application of this approach in Ocular Oncology. The Authors analyze the implementation and outcomes of a trained MDTB in a tertiary ocular oncology referral center. Methods A retrospective descriptive analysis of MDTB meetings of patient with ocular and periocular cancers, over a 12-months period, was carried out. Data were grouped by main site involved, topics discussed and final clinical decisions therefore taken. Meetings were held by a constant ‘Core team’ or – when required – by a broader ‘Extended team’. Results During the observational period 86 cases were discussed. In 27 patients ocular surface tissues were involved (31%), in 25 patients orbital tissues (29%), in 22 patients eyelids (26%), and in 12 patients intraocular tissues (14%). In 13 cases (15%) naïve or referred new patients, in 34 cases (40%) imaging or histopathologic reports and in 39 cases (45%) treatment plans were discussed. Regarding final decisions, a treatment plan was scheduled in 47 cases (55%) and a diagnostic ascertainment was required in 27 patients (31%); locally advanced and/or systemic diseases were referred or teamed up with other specialists in 12 cases (14%). Conclusions Ocular Oncology multidisciplinary team, by sharing expertise of different specialists, ensures a comprehensive evaluation of patients improving the accuracy of diagnosis and staging upon which planning a proper treatment. Further studies are needed to assess if this approach may also improve the outcomes and prognosis of patients.
Quality Management System Implementation Status and Its Associated Factors Among Clinical Staffs at Governmental Hospitals in Addis Ababa, Ethiopia
Authors: Getachew Yeworkwuha , Mekuria Mulugeta , Ketsela Admasu , Gebremariam Zewdu Minwuyelet , Kebede Mebratu Abraha 
Published: August 2022

Abstract
Introduction: Quality management system is a set of coordinated activities to direct and control an organization in order to continually improve the effectiveness and efficiency of its performance. So, information about the status of health sector quality management system implementation is necessary. However, there is limited information about the quality management system implementation in the study area as well as at national level.Objective: the aim of this study is to assess quality management system implementation and its associated factors at governmental hospitals in Addis Ababa, Ethiopia. Methods: An institution-based cross-sectional study was conducted among 422 health care providers working in public hospitals in Addis Ababa. Simple random technique was used to select both the study settings and study participants. Data were collected by using structured written questionnaire after obtaining written consent from the respondents. The collected data were entered into Epi-data version 3.1 and analyzed using SPSS Version 25. Bivariate and multivariate analysis was done. Variables which had p-value <0.05 at 95%CI were considered as statistically significant association with dependent variable in multivariate analysis. Result was presented in text, table and figures. Result: A total of 422 study participants were participated in the study with the response rate 100%. The mean age of the study participants was 31.46 (SD=5.77) years. The majority (44.5%) of the study participants were below 30 years of age and 55.0% were female by sex. This study revealed that nearly 52% of quality management system were not implemented in the selected health facilities. Being 35 years and above (AOR =1.99) in age, ever heard about QMS (AOR 1.56) by the staff, and those staff knows the availability of QMS (AOR= 2.31) were among variables that identified as predictors of QMS implementation in the study area.Conclusion and recommendation; This study concluded that the level of QMS implementation in the current study area is suboptimal. Age of the study participants, previous hearing about QMS, and knows the availability of QMS were among variables that identified as predictors of QMS implementation in the study area. Therefore, health facilities are recommended to educate their staff about QMS implementation.
Present and future: the effects and possible solutions of microplastics in the marine/aquatic environment
Authors: Sharma Anuj , Prakash Sanchu , B.R Malavika , Mathew Meril Mary , Arrigo Federica , Lakshmi Sreeja , Elumalai Preetham , Freitas Rosa , Faggio Caterina 
Published: August 2022

Abstract
Anthropogenic activities have degraded the marine ecosystem badly, among which microplastic (MPs) is the primary cause. The use of MPs is increasing at extraordinary haste while the recycling and reuse are very low. They are dumped in water bodies that sequentially enter the marine ecosystem. Recently scientists have observed the presence of MPs in various tissues such as the gastrointestinal tract and some immune organs. The major problem arises when it affects the human population severely. The consumption of MPs-affected fish cause accumulation in the food chain resulting in biomagnification. It affects human health by interfering with the gut microbiome, immune response, etc. We can decrease the impact of MPs by reducing their production and detecting them in aqua-consuming organisms. There are different techniques to diagnose the concentration of MPs inside marine organisms before processing. Removal of the gut of marine food organisms before consumption is also an excellent way to reduce the impact of MPs on health, but it is not possible for small fish. So, some limits should be applied to impose the production of MPs and enhance the use of biodegradable products for human health considerations. Some protocols should be set on the boundary of MPs’ concentration for fish marketing and processing.
Alteration of gut microbiota in polycystic ovary syndrome patients and the correlated clinical parameters: a cross-sectional analysis study from Chinese women
Authors: Huang Jianqin , Su Chunlin , Zhang Xiaojin , Dai Ruoxi , Jiang Liwen , Zhang Tingting , Sun Yan , Zhu Zhiling 
Published: August 2022

Abstract
Purpose
To investigate gut microbiota in patients with PCOS and explore their relationships with metabolic and endocrine parameters.
Methods
The fecal samples obtained from patients with PCOS (n = 90) and healthy women without PCOS (n = 30) were analyzed by 16S rRNA gene sequencing. Anthropometry parameters of all subjects were measured and bloods were collected to detect endocrine, biochemical indexes and brain-gut peptides. Spearman correlation between 31 clinical parameters and 31 CAGs was performed to explore the relationship between gut microbiota and PCOS phenotype.
Results
Compared to the healthy controls, women with PCOS showed significant higher levels of weight, BMI, waist circumference, hip circumference, WHR, LH, LH/FSH, E2 and T. The PCOS group owned lower richness than the control both in PD whole tree and sobs indexes. There was no significance in β diversity between the two groups. LDA analysis showed that Bacteroides coprocola, Lachnoclostridium, Bifidobacterium pseudocatenulatum, Veillonella, Sutterella wadsworthensis, Megasphaera micronuciformis, Clostridium butyricum and Paraprevotella xylaniphila were the dominant bacteria in the PCOS patients. CAG 6 and 19, which were enriched in PCOS group, showed a positive correlation with the obesity, inflammation and hyperlipemia but a negative correlation with the Ghrelin and 5-HT. CAG18, 21, 25, 26 and 27 were enriched in controls but an opposite trend.
Conclusion
Diversity and abundance of gut microbiota decreased in patients with PCOS, which presented a negative correlation with the Ghrelin and 5-HT and positively connected to metabolic disorder and inflammation. The alteration of gut microflora might be an important pathological factor in the PCOS.
The effect of CO2 in the feed stream of TRM process compared to the partial oxidation of methane.
Authors: Soares Auta , Roseno Karina T. C. , Giudicci Reinaldo , Schmal Martin 
Published: August 2022

Abstract
In this work, we studied the effect of CO2 in the feed stream of the TRM process performance of nickel supported on LaFeO3 perovskite for hydrogen production compared to the POM reaction. The perovskite and nickel supported on LaFeO3 were synthesized and characterized by Thermogravimetric Analysis (TGA/DTA), X-Ray Diffraction (XRD), Transmission Electron Microscopy (TEM), and Programmed Reduction Temperature (TPR). The catalytic tests were carried out in temperatures varying from 700 to 800°C with feed flow of 350 cm3/min and 200 cm3/min for TRM and POM, respectively. The hydrogen selectivity for the tri-reforming was 78%, while for the partial oxidation reaction, only 55% H2 at 700°C. Results showed that the hydrogen selectivity for the Ni/LaFeO3 catalyst is significantly higher for the tri-reforming process, suggesting that CO2 enhanced the hydrogen selectivity compared to the partial oxidation of methane. Analyses by Raman spectroscopy and thermogravimetric calculations showed structural modifications of the catalysts after the reaction. The Raman spectrum showed segregated NiO and Fe3O4 and low carbon formation at 700°C. The proposed mechanism suggests methane and oxygen adsorbed preferentially on metallic Ni0 sites and CO2 on Fe2O3 sites.