bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pemetaan Penelitian Terkait Keamanan Data di Indonesia
Authors: Yuadi Imam , Khusniah Lailatul 
Published: November 2022

This research aims to be able to find out the tendency to use keywords in research related to data security in Indonesia. This study uses the method of bibliometric studies. The data was taken from a database published by Scopus in 2019 to 2021. Bibliometric data analyzed and visualized using VosViewer. Total research after the limit was generated 2,497 data globally and research related to security data in Indonesia found 31 studies in the form of journal articles. In Indonesia found 13 main keywords used in the study, namely Data Hiding, Data Protection, Data Security, Information Security, Reversible Data Hiding, Steganography, Cloud Computing, Cryptography, Network Security, Pixels, Security, and Security Of Data. Then after analysis was concluded that keyword Cryptography and Network Security are most often used in research related to data security globally and in Indonesia.

ABSTRAK
Penelitian ini bertujuan agar dapat mengetahui penelitian terkait Keamanan data di Indonesia. Penelitian ini menggunakan metode Studi bibliometrik. Data diambil dari database yang diterbitkan oleh Scopus dalam tahun 2019 hingga 2021. Data bibliometrik yang dianalisis dan divisualisasi menggunakan VosViewer. Hasilnya ditemukan Total penelitian setelah dilakukan limit dihasilkan 2.497 data secara global dan penelitian terkait data security di Indonesia ditemukan 31 penelitian berbentuk artikel jurnal. Di Indonesia ditemukan 13 keyword utama yang digunakan dalam penelitian yaitu Data Hiding, Data Protection, Data Security, Information Security, Reversible Data Hiding, Steganography, Cloud Computing, Cryptography, Network Security, Pixels, Security, Dan Security Of Data. Kemudian setelah dianalisis didapat kesimpulan bahwa keyword Cryptography dan Network Security paling sering digunakan dalam penelitian terkait keamanan data secara global dan di Indonesia.
Twitter-diplomatiasta
Authors: Rikkonen Lassi , Isotalus Pekka 
Published: November 2022

Kansainvälisten suhteiden viestintäympäristö on käynyt viime vuosikymmenten aikana läpi valtavia muutoksia. Viime vuosina erityistä huomiota on saanut Twitterin nousu julkisen diplomatian ja maailmanpolitiikan merkittäväksi areenaksi. Valtiojohtajat, hallitukset ja ulkoministeriöt ympäri maailman ovat valinneet Twitterin keskeiseksi sosiaalisen median viestintäkanavakseen. Tässä tutkimuksessa tarkastellaan suomalaisten ulkopolitiikan ammattilaisten (N = 125) viestintätoimijuutta ja vuorovaikutusosallisuutta Twitterissä. Lisäksi tavoitteena oli tutkia heidän käsityksiään Twitter-diplomatian hyödyistä Suomen kannalta. Viestintätoimijuuden suhteen tarkastelun keskipisteessä olivat henkilökohtaiselle osallistumiselle annetut merkitykset. Vuorovaikutusosallisuus taas liittyy ennen kaikkea yksilön kykyyn olla osana viestintätilannetta ja siten suhteessa muihin viestijöihin. Se tarjoaakin Twitter-diplomatiaan osallistumista selventävän käsitteellisen viitekehyksen, koska siinä ilmenevät viestintäosaamisen kaikki tasot tulkintaosaamisesta viestiosaamiseen. Twitter-diplomatian hyötyjen osalta tarkastelun kohteena olivat mediajulkisuuteen, suhteiden rakentamiseen sekä maineeseen ja maakuvaan liittyvät asiat. Verkkokyselylomakkeella kerätyn aineiston analyysissa yhdisteltiin määrällisiä ja laadullisia tutkimusmenetelmiä. Tulosten mukaan Twitteriä työssään käyttävät diplomaatit ja muut ulkopolitiikan ammattilaiset suhtautuvat positiivisesti sen tarjoamiin hyötyihin julkisen diplomatian kannalta. Osallistujat jaoteltiin viestintätoimijuuden suhteen kolmeen viestijätyyppiin riippuen siitä, korostuivatko heidän vastauksissaan vuorovaikutukseen (julkiset diplomaatit) vai viestinnän näkyvyyteen ja tehokkuuteen (tiedottaja-diplomaatit) liittyvät asiat tai pitivätkö he henkilökohtaista osallistumista lainkaan tärkeänä (häivediplomaatit). Vuorovaikutusosallisuus oli sitä korkeampaa, mitä tärkeämpänä henkilökohtaista osallistumista pidettiin. Vuorovaikutusosallisuus oli myös yhteydessä korkeampiin arvioihin Twitter-diplomatian kokonaishyödyistä sekä suhteiden rakentamiseen ja ylläpitoon liittyvistä hyödyistä.
Development of the Composition and Technology of Orally Dispersed Tablets Based on Ethylthiobenzimidazole Fumarate
Authors: Kasymov I. D. , Basevich A. V. , Marchenko A. L. , Vainshtein V. A. 
Published: November 2022

Introduction. The article presents the results of the development of the composition and technology of orally dispersed tablets of ethylthiobenzimidazole fumarate – a new actoprotective and adaptogenic agent.Aim. Development and substantiation of the composition and technology of orally dispersed tablets based on ethylthiobenzimidazole fumarate.Materials and methods. The technological properties of tablet samples were studied according to the methods of the State Pharmacopoeia of the XIV edition using the PGR-10 tablet press (LLC "LabTools", Russia), TBH 125 TDP tablet hardness tester (ERWEKA GmbH, Germany), ZT 322 m tablet disintegration tester (ERWEKA GmbH, Germany), TAR 220 abrasion tester (ERWEKA GmbH, Germany).Results and discussion. As a result of the study, the composition of orally dispersed tablets based on a new substance – ethylthiobenzimidazole fumarate was developed and justified. As a justification, the data of the analysis of the technological properties of the substance and excipients, the results of a multifactorial experiment planned using the Minitab 17 program, as well as data on the strength characteristics of the tablets obtained and the dependence of the disintegration time of the tablets and their strength characteristics on the pressing pressure are given.Conclusion. Based on the results of the study, the optimal composition of orally dispersed tablets based on ethylthiobenzimidazole fumarate is proposed.
Hypothyroidism predicts worsened prognosis in patients undergoing percutaneous coronary intervention
Authors: Cohen Ben , Bental Tamir , Perl Liat , Vaknin Assa Hana , Codner Pablo , Orvin Katia , Barkan Yeela Talmor , Levi Amos , Kornowski Ran , Perl Leor 
Published: November 2022

BackgroundThe link between thyroid dysfunction and cardiovascular disease is well established. Hypothyroidism has been significantly associated with increased risk of dyslipidemia, atherosclerosis and heart failure. However, little is known regarding its effect on patients undergoing percutaneous coronary intervention (PCI).AimThe aim of study was to examine the impact of concomitant hypothyroidism on mortality and major adverse cardiac event (MACE) in patients undergoing PCI.MethodsThe Rabin Medical Center PCI registry includes all consecutive patients who have undergone PCI between 2004 and 2020. We identified patients with prior diagnosis of hypothyroidism, and compared rates of mortality and MACE (comprising death, myocardial infarction, target vessel revascularization and/or coronary bypass surgery).ResultsAmong 28,274 patients, 1,922 (6.8%) were found to have hypothryoidism. These patients were older (70.3 ± 10.4 vs. 66.0 ± 11.8 y.o, P &lt; 0.001) and more likely to be women (34.2% vs. 26.1%, P &lt; 0.001). They had a higher prevalence of atrial fibrillation (10.8% vs. 7.7%, P &lt; 0.001), chronic renal dysfunction (25.1% vs. 18.7%, P = 0.04) and dementia (2.9% vs. 1.8%, P = 0.004). PCI was performed on ACS setting in 52–54% of patients in both groups (p = 0.569). Unadjusted 5-year rates of all-cause mortality (26.9% vs. 20.3%, P &lt; 0.001) and MACE (40.3% vs. 29.4%, P &lt; 0.001) were higher for hypothyroid patients. A propensity match score was able to form 672 matched pairs of HT and control patients, showing similar results. Moreover, following multivariate analysis, TSH as a continuous parameter was associated with a higher risk of mortality and MACE (HR, 1.06 per additional 1 mIU/L; CI, 1.02–1.11; P &lt; 0.001 and HR, 1.07; CI, 1.02–1.12; P &lt; 0.001, respectively) at 5-year follow up.ConclusionIn our study, hypothyroidism confers worse outcomes in patients undergoing PCI. Further research is needed to establish effective ways to mitigate this augmented risk.
Perioperative outcomes of robotic lobectomy for early-stage non-small cell lung cancer in elderly patients
Authors: Gallina Filippo Tommaso , Tajè Riccardo , Forcella Daniele , Gennari Valeria , Visca Paolo , Pierconti Federico , Coccia Cecilia , Cappuzzo Federico , Sperduti Isabella , Facciolo Francesco , Melis Enrico 
Published: November 2022

IntroductionMinimally invasive surgery has become the standard for the early-stage non-small cell lung cancer (NSCLC). The appropriateness of the kind of lung resection for the elderly patients is still debated.MethodsWe retrospectively reviewed patients with older than 75 years who underwent robotic lobectomy between May 2016 to June 2022. We selected 103 patients who met the inclusion criteria of the study. The preoperative cardiorespiratory functional evaluations were collected, and the risk of postoperative complications was calculated according to the Charlson Comorbidity Index, the American College of Surgery surgical risk calculator (ACS-NSQIP), EVAD score, and American Society of Anesthesiology (ASA) score. The patients were divided in two groups according to the presence of postoperative complications.ResultsForty-three patients were female, and 72.8% of the total population were former or active smokers. Thirty-five patients reported postoperative complications. The analysis of the two groups showed that the predicted postoperative forced expiratory volumes in the first second (FEV1) and forced vital capacity (FVC) were significantly lower in patients presenting postoperative complications (p=0.04). Moreover, the upstaging rate and the unexpected nodal metastases were higher in the postoperative complication groups.ConclusionRobotic-assisted lobectomy for early-stage lung cancer is a safe and feasible approach in selected elderly patients. The factors that could predict the complication rate was the predicted postoperative FEV1 and the nodal disease.
Pathological complete remission in ALK-positive lung cancer patient after multiple lines of conversion therapy
Authors: Que Dan , Zou Hongbo , Mao Bijing , Zhang Huan , Liang Wei , Liu Qin , Ke Leiyu , Guo Lijie , Xie Qichao 
Published: November 2022

IntroductionTraditional therapeutic approaches for the treatment of advanced non-small-cell lung cancer (NSCLC) are based on chemotherapy. However, the discovery and understanding of oncogenic driver alterations has led to the development of targeted therapies that have substantially improved patient outcomes. Still, to date, there have been no reports of patients with advanced anaplastic lymphoma kinase (ALK)-positive lung cancer achieving clinical complete response (cCR) in the systemic lesion and pathological complete remission (pCR) in primary lung lesion after multiple lines of conversion therapy.MethodsIn this case, a 55-year-old man was diagnosed with ALK-positive, stage IV lung adenocarcinoma using immunohistochemistry and next generation sequencing (NGS) tests.ResultsCrizotinib and two other ATP-competitive ALK inhibitors, ceritinib and alectinib, were used respectively as first-line, second-line, and third-line therapy. The patient received treatment with crizotinib and achieved partial response (PR), but 5 months later the efficacy was evaluated as progressive disease (PD). Ceritinib was used as the second-line treatment, but the disease progressed 6 months later. Alectinib was used as the third-line treatment, but the efficacy was evaluated as PD. From April 2019 to November 2019, the patient received 4 cycles of induction chemotherapy with pemetrexed/carboplatin/bevacizumab and then switched to pemetrexed/bevacizumab as the fourth-line treatment, and received the fifth line treatment, cetuximab/paclitaxel liposome/nedaplatin, for 1 cycle, but the disease still progressed. Then the patient received the sixth line of treatment, camrelizumab/lorlatinib, for 9 antitumor cycles, resulting in PR. The patient underwent surgery followed by maintenance treatment with lorlatinib and achieved cCR. To our knowledge, this is the first documented case of cCR in a patient with ALK-positive advanced lung adenocarcinoma treated with multiple lines of therapy followed by surgical treatment.DiscussionThis case reveals the possible survival benefit of immunotherapy after multiple line treatment in ALK-positive advanced lung adenocarcinoma, indicating that it is possible find new therapeutic targets based on NGS molecular detection and provide precise therapeutic strategies for clinical practice when drug resistance or progression occurs in cancer therapy.
Manipulating plasma thyroid hormone levels alters development of endothermy and ventilation in nestling red-winged blackbirds
Authors: Sirsat Tushar S. , Sirsat Sarah K. G. , Price Edwan R. , Pineda Megan , Dzialowski Edward M. 
Published: November 2022

Thyroid hormones are key regulators of development and metabolism in vertebrates. During the nestling period, young of altricial species transition from an ectothermic phenotype to an endothermic phenotype. Red-winged blackbirds are an altricial species that exhibit an increase in plasma 3,3’, 5-triiodo-L-thyronine (T3) levels during the first 5 days post-hatch (dph), begin to develop endothermic metabolic responses by 7 dph, and fledge within 10 days of hatching. We propose that thyroid hormones play an important role in regulating development of endothermy during the nestling period in altricial birds. To better understand the effects of thyroid hormones on endothermic metabolic development in an altricial species, we treated nestling red-winged blackbirds on 2, 3, and 5 dph with either methimazole (MMI) to induce hypothyroidism or supplemental T3 to induce hyperthyroidism. We then measured on 5, 7, and 9 dph morphology and whole animal O2 consumption (V˙o2) and ventilation in the thermal neutral zone and during gradual cooling. Treatment of nestlings with MMI resulted in lower plasma T3 levels on 5 dph that recovered by 7 dph, while supplementing with T3 did not affect plasma T3 levels on 5, 7 and 9 dph. Treatment with MMI resulted in smaller nestlings with smaller hearts and structural characters such as wing chord and femur length, but larger lungs and kidneys. Treatment with T3 produced smaller nestlings with smaller body masses and shorter femur and tarsus lengths. The development of V˙o2 and ventilation endothermic responses to gradual cooling in MMI treated nestlings were delayed when compared with control nestlings. In 9 dph nestlings, hypothyroidism resulted in alterations in the responses of ventilation frequency and tidal volume to cooling when compared with the control nestlings. Supplemental T3 had no effect on the development of V˙o2 and ventilation in the thermal neutral zone or in response to cooling. Our data suggest plasma thyroid hormone levels play an active role in the systemic development of endothermic capacity and the development of ventilatory control. In the nestling avian, multiple systems develop in concert to produce an endothermic phenotype, but reduced thyroid hormone delays maturation of endothermic capacity.
Effect of video tutorial delivery method on D/HH students’ content comprehension
Authors: Almalhy Khalid M. 
Published: November 2022

IntroductionUsing video tutorials to deliver instructional content has become common practices nowadays. However, it is required to investigate how to implement new methods to deliver instructional content to deaf students to ensure success of their learning and reduce their reliance on personnel support or consultation from hearing peers. Therefore, and in light of cognitive theory of multimedia learning, this study experimented three different video tutorial methods to deliver instructional content that are tailored to deaf students’ learning needs. The three methods included: (a) sign language only, (b) captioned text only, and (c) sign language and captioned text combined.MethodsThe study applied a mixed methods research design using pretest-posttest quasi-experimental design (tests scores) and qualitative research design (interviews). Fifty-four undergraduate deaf students from a large university in Saudi Arabia participated in this study, and of those participants, fifteen deaf students participated in semistructured interviews.Results and discussionOne-way analysis of variance results showed that using video tutorial that presents declarative content with captions only was significantly effective in comparison with the other methods. While the video tutorial that presents procedural content with sign language only was significantly effective in comparison with the other methods. Interview results confirmed the quantitative results. Practical and theoretical implications are discussed.
Adverse childhood experiences as risk factors for recurrent admissions in young psychiatric inpatients
Authors: Fellinger Matthäus , Knasmüller Philipp , Kocsis-Bogar Krisztina , Wippel Andreas , Fragner Laura , Mairhofer Dunja , Hochgatterer Paulus , Aigner Martin 
Published: November 2022

BackgroundPatients who require psychiatric inpatient treatment early in life are a particularly at-risk population. Factors such as adverse childhood experiences (ACEs) are, however, not well studied in those requiring psychiatric inpatient treatment during both childhood or adolescence and adulthood. Thus, the aim of the current study was to investigate, in young adult inpatients, the risk factors for prior admissions in Child and Adolescent Psychiatry, with a focus on ACEs.Materials and methodsAn explorative population-based systematic chart investigation of psychiatric inpatients aged 18–25 was conducted at the University Hospital Tulln, Austria. Data analysis was done with descriptive methods and Pearson’s chi- squared-, Fisher’s exact-, Mann–Whitney-U-tests and predictive logistic regression models.ResultsThe sample comprised 390 inpatients (51.8% female), with an average age of 20 years at first psychiatric hospital admission. Those with a former child and adolescent psychiatry inpatient treatment (10.3%) were predominantly female (77.5%). Their number of documented ACEs was increased compared to those without former child and adolescent psychiatry admissions (2 vs 1.1), with up to twice as many experiences of family dysfunction, neglect or abuse. Sexual abuse (OR: 3.0), having been an adopted or fostered child (OR: 4.5), and female sex (OR: 3.0) were identified as main risk factors. Furthermore, former child and adolescent psychiatry inpatients suffered from higher rates of psychosomatic or personality disorders, comorbidities and functional impairment, and were readmitted twice as often in young adulthood.ConclusionYoung adult inpatients with reoccurring psychiatric inpatient treatments have increased rates of severe ACEs. Thus, special attention should be given to identifying ACEs, evaluating needs for psychosocial support and therapy, and meeting these needs after discharge.
Changes in general practice use and costs with COVID-19 and telehealth initiatives: analysis of Australian whole-population linked data
Authors: Butler Danielle C , Joshy Grace , Douglas Kirsty A , Sayeed Muhammad Shahdaat Bin , Welsh Jennifer , Douglas Angus , Korda Rosemary J ,   The ANU Telehealth in Primary Care Study team
Published: November 2022

BackgroundIn response to the COVID-19 pandemic, general practice in Australia underwent a rapid transition, including the roll-out of population-wide telehealth, with uncertain impacts on GP use and costs.AimTo describe how use and costs of GP services changed in 2020 — following the COVID-19 pandemic and introduction of telehealth — compared with 2019, and how this varied across population subgroups.Design and settingLinked-data analysis of whole-population data for Australia.MethodMulti-Agency Data Integration Project data for ∼19 million individuals from the 2016 census were linked to Medicare data for 2019–2020. Regression models were used to compare age- and sex-adjusted GP use and out-of-pocket costs over time, overall, and by sociodemographic characteristics.ResultsOf the population, 85.5% visited a GP in Q2–Q4 2020, compared with 89.5% in the same period of 2019. The mean number of face-to-face GP services per quarter declined, while telehealth services increased; overall use of GP services in Q4 2020 was similar to, or higher than, that of Q4 2019 for most groups. The proportion of total GP services by telehealth stabilised at 23.5% in Q4 2020. However, individuals aged 3–14 years, ≥70 years, and those with limited English proficiency used fewer GP services in 2020 compared with 2019, with a lower proportion by telehealth, compared with the rest of the population. Mean out-of-pocket costs per service were lower across all subgroups in 2020 compared with 2019.ConclusionThe introduction of widespread telehealth maintained the use of GP services during the COVID-19 pandemic and minimised out-of-pocket costs, but not for all population subgroups.
Assistência de Enfermagem a pessoas com Doença Falciforme: uma revisão integrativa
Authors: Vilela Réche da Motta Franciane , Muniz dos Reis Rocha Pâmella , Francy da Silva Mendes Sophia , Soares de Abreu Giovana , Mariana Alves da Cruz Carla , Andrade e Silva Érika 
Published: November 2022

Objetivo: Conhecer ações de enfermagem para assistência integral à pessoa com Doença Falciforme nos serviços de saúde e identificar a presença desses cuidados nos serviços, a partir da literatura científica. Método: Trata-se de uma revisão integrativa da literatura com recorte temporal de 2013 a 2019. Resultados: Selecionaram-se nove artigos para análise e construção dessa revisão. Originaram-se duas categorias de discussão: O cuidado de enfermagem às pessoas com DF na Atenção Primária; O cuidado de enfermagem às pessoas com DF na Atenção Secundária e na Rede de Urgência e Emergência. Conclusão: Identificaram-se ações como: a orientação aos pacientes e familiares acerca de alimentação, uso de sulfato ferroso, palestras educativas sobre a doença, olhar e escuta ativa, prestação de conforto e bem-estar ao paciente, entre outros. Percebeu-se a carência de estudos e aperfeiçoamento em relação ao manejo da DF por parte dos profissionais de enfermagem.
Conhecimento da equipe de enfermagem sobre a parada cardiorrespiratória em adultos
Authors: Dos Santos Elisa Adriana , Martins Bock Patricia , Vanz Ana Paula , Martins Edna Thais Jeremias 
Published: November 2022

Objetivo: avaliar o conhecimento da equipe de enfermagem sobre o atendimento de uma parada cardiorrespiratória (PCR) em adultos com identificação dos fatores associados ao conhecimento. Metodologia: estudo quantitativo, transversal, realizado com profissionais de enfermagem da região do Vale do Paranhana, no Rio Grande do Sul, em 2018. Os dados foram coletados por meio de um questionário autoaplicável, com variáveis socioeconômicas e questões sobre o conhecimento da PCR. Foi considerado grupo “bom conhecimento”, aqueles que acertavam quatro questões primordiais para atendimento de PCR. Já conhecimento limitado foi quem acertou uma, duas ou três questões. Os dados foram coletados e analisados pelos softwares Survey Monkey e Statistical Package for Social Science (SPSS). Resultados: participaram 100 profissionais de enfermagem. Identificou-se que 37% possuíam bom conhecimento para atendimento de PCR. A renda maior que R$5.200,00 foi associada ao maior conhecimento (RP 2,1; IC95%=1,1-3,9; P=0, 017). Conclusões: o conhecimento para atendimento de uma PCR é limitado, e pode impedir a sobrevivência e o manejo de vítimas de PCR.