bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adolescents and young adults with social withdrawal in France: Sociodemographic characteristics and validation of the French version of the Hikikomori Questionnaire-25 (HQ-25)
Authors: Benarous Xavier , Guedj Marie-Jeanne , Lomelo Filomena , Mohamed Faizla , Teo Alan Robert , Pellerin Hugues 
Published: January 2025

Background: Clinical situations marked by severe social withdrawal in youths are increasingly recognized as an important public health issue in European countries, while the relation with the hikikomori syndrome initially described in Japan remains poorly investigated. Aims: This study aims to describe the sociodemographic features of adolescents and young adults with social withdrawal in French and to validate a French version of the Hikikomori Questiuonnaire-25 (HQ-25). Method: An online questionnaire was completed by 450 participants aged 13 to 25 years. In addition to socio-demographic features, participants were questioned about several aspects of social withdrawal behaviors and a version of the HQ-25 previously adapted in French by a group of patients and clinician experts. Results: A minority of participants was found ‘at-risk HKM’ (3.6%). They were approximately younger, and lived more frequently with their parents, with balanced sex ratio and no differences regarding the educational level. The level of distress and concern about physical/mental health did not discriminate between the two groups. Regarding psychometric properties of the HQ-25, Cronbach’s alpha of the total was .93, the ICC was .74, and the indices of fit found in the confirmatory factorial analysis of the original three-factor solution were robust. Conclusions: Considering the social invisibility and the barriers to care access of adolescents and young adults with hikikomori, the development of a self-assessment instrument with good psychometric properties is regarded as an important first step.
The Mediating Role of Commercial FOMO Between Adolescents’ Need to Belong and Psychological Distress: Advertising Implications on Mental Health
Authors: Huțul Tudor-Daniel , Mațcu-Zaharia Mara , Huțul Andreea , Karner-Huțuleac Adina 
Published: January 2025

The present study was designed to investigate the impact of advertising on adolescents’ mental health. To achieve this, we sought to test the mediating effect of commercial fear of missing out (FOMO) related to gadgets and clothing items on the relationship between the need to belong and psychological distress. The research was conducted on a sample of 335 Romanian adolescents (54.9% female, 45.1% male), aged between 14 and 19 years old (M = 17.76; SD = 1.57). They filled out questionnaires that measured FOMO related to gadgets and clothing items, psychological distress, need to belong, and some socio-demographic data. The findings underscored the direct association between the need to belong and psychological distress, as well as the mediating effect of FOMO related to gadgets and clothing on this relationship. This study contributes to advancing understanding of the connections between commercial FOMO associated with gadgets and clothing, psychological distress, and the need to belong, while highlighting the negative impacts of advertising on adolescent mental health. Theoretical and practical implications of the current study are discussed.
Assessing hazards of ancient landslide clusters in the Lancang river basin using multi-temporal remote sensing: A case study of Chaya county
Authors: Li Xude , Zhang Jiajia , Tian You , Zhao Yu 
Published: January 2025

The reactivation of ancient landslides typically exhibits large scales, significant destructive power, and adverse consequences. This has long been a pressing issue for the planning and construction of major projects, and the safety of urban areas. Using high-resolution remote sensing images, SBAS-InSAR, unmanned aerial vehicle (UAV) surveys, and rainfall data, we delved into the evolution, ongoing deformation, and damage of ancient landslide clusters in the Lancang River Basin on the Tibetan Plateau. Two high-precision remote sensing images from 1965 and 2019 were used to analyze the spatial changes of this landslide cluster. The examination of 292-scene radar images and rainfall data from 2018 to 2022 illuminated the spatio-temporal deformation characteristics and trends of the landslide clusters. Our fieldwork indicated that areas with deformation rates exceeding 20 mm/yr, as detected using SBAS-InSAR, have experienced various degrees of collapse and slippage in recent times. Particularly alarming is that areas with deformation rates of up to 68 mm/yr are on the brink of obstructing the river. Rainfall, river slope cutting, and human engineering activities constitute the factors driving continuous deformation failure, resulting in different slip patterns of the landslide cluster. We numerically simulated the hazard potential in susceptible areas using the Massflow software. The results suggest that areas subjected to slippage will pose significant risks to structures and a possibility of river blockage.
A case report on azathioprine induced anagen effluvium, plica polonica, and bicytopenia in a patient of vitiligo
Authors: Gowda Shreya K , Rout Arpita N , Panigrahi Ashutosh , Sirka Chandrashekar 
Published: January 2025

Background Anagen effluvium is described as abrupt hair loss during the anagen phase due to reduced follicular mitotic activity. Chemotherapeutic medicines, toxic metals, and sporadically bismuth, levodopa, colchicine, and cyclosporine are often implicated in etiology. Plica polonica is a rare disorder that develops when the scalp hair mats completely and abruptly, resulting in an extended stiff mass of hair that resembles dreadlocks. Objective We are describing this case because it is unusual to see plica polonica linked with azathioprine-induced pancytopenia in the literature and since the source of the condition was cuticular damage to the hair shaft as a result of the medication rather than carelessness or excessive bathing of the patient’s hair. Case description A 32-year-old lady presented to dermatology OPD, with vitiligo over bilateral forearm and lips for 6 months. She was started on azathioprine 50 mg daily for the past 1 month, and then she complained of sudden onset of extensive hair loss on attempting to comb her hair associated with matting of rest of uncombable hairs, multiple oral ulcers, and mild grade fever for 15 days. The possibility of systemic lupus erythematosus and azathioprine-induced anagen effluvium and neutropenic ulcers was thought. Results We started on injectable granulocyte colony-stimulating factor for 3 days, and antibiotics and antifungals for 1 week. Improvement in clinical (oral ulcers, fever) and hematological profiles were noted. Conclusion Although azathioprine is not often associated with the development of anagen effluvium, it is probable that the patient’s abrupt pancytopenia caused damage to the hair shaft, which resulted in hair loss, and cuticular damage to the hair shaft, which led to the formation of Plica.
Utilisation patterns of immunomodulators and pregnancy outcomes in systemic lupus erythematosus: Insights from Korean national data
Authors: Jung Yu-Seon , Song Yeo-Jin , Lee Hyeon Ji , Kim Eunji , Cho Soo-Kyung , Sung Yoon-Kyoung , Jung Sun-Young 
Published: January 2025

Objectives To investigate the trends in immunomodulator use and pregnancy outcomes among pregnant women with systemic lupus erythematosus (SLE), a condition requiring medication to maintain disease activity. Methods This descriptive study used data from the National Health Information Database in Korea from 2002 to 2018. We included 5,044 pregnancies initiated between 2005 and 2017 in 3,120 SLE patients. Annual trends in SLE therapy, drug utilisation patterns during the preconception and pregnancy periods, and pregnancy outcomes were analysed. Results Pregnancy compatible immunosuppressant (PC-IS) and hydroxychloroquine use during the first trimester were 10.7% and 41.4%, respectively. Most SLE medications exhibited a decline in usage from the preconception period to the first trimester. A prescription rate of 0.9% for pregnancy incompatible immunosuppressants (PIC-IS) was observed during the first trimester, and the incidence of live births, stillbirths, and abortions remained consistent from 2005 to 2017. Conclusions Insufficient usage of hydroxychloroquine and PC-IS, along with a reduction in PIC-IS usage primarily during early pregnancy rather than before conception, highlights the unmet need for preconceptional family planning with appropriate medication management strategies in SLE pregnancies.
An ethical model for smart home-based elder care
Authors: Cao Lina , Feng Shengjie , Chen Kunfeng , Wu Xinchun , Jia Yuxiu 
Published: January 2025

Background The smart home-based elder care presents a promising technological solution to address the challenges of aging. However, it has also unveiled a spectrum of ethical concerns, which may cause older adults to submit to negative emotions and psychological pressure. Aim To delineate the ethical dilemmas encountered by older adults in the context of smart home-based elder care, and to construct a model that elucidates the ethical issues across different dimensions. Research design This study follows a qualitative phenomenological research design. Participants and research context The sample comprised 15 older adults and 10 adult children in two communities in Jinan, Shandong, China. Structured, in-depth interviews were performed to collect data and the Colaizzi descriptive analysis framework was adopted to analyze data. An ethical dilemma model was constructed based on framework of the Society Ecosystems Theory. Ethical considerations The proposal was approved by the Research Ethics Committee of the Second Hospital of Shandong University, China. Participation in this study was voluntary. Written and verbal consent was gained. All recordings were kept under the principle of confidentiality. Results Ethical dilemmas of smart home-based elder care were grouped into three themes with 10 sub-themes, and a model composed of three systems was built based on these findings. Discussion The ethical dilemmas experienced by the older adults with smart home-based elder care were various and multi-layered, which could be elucidated by the ethical dilemma model. Conclusion The model emphasizes the necessity for collaborative efforts among the whole society and the elderly individuals. Tailored support strategies should be implemented to address the ethical dilemmas of the macro, meso, and micro system. The results may improve the elderly population to receive a more content and convenient elder care experience.
Monetary Policy, Interbank Liquidity, and Lending Behavior of Banks in India
Authors: Ansari Md Gyasuddin , Sensarma Rudra 
Published: January 2025

We investigate the role of interbank liquidity in monetary policy transmission in India. We employ standard and dynamic panel regression methods to analyze data for 48 commercial banks during the period 1999–2018 and 2019–2023. We find a significant role of interbank liquidity in easing the negative impact of monetary policy tightening on bank lending during the first period when the reliance of banks on the interbank market was rising. We also find a heterogeneous role of interbank liquidity in monetary policy transmission across public sector and private sector banks. The policy implication for the monetary authority in India is that, at times of high reliance on the interbank market, managing the net liquidity positions of banks is necessary to realize the desired effects of monetary policy. JEL Codes: C23, E52, E58, G21
Contextualizing Psychological First Aid for the Pacific Island Countries
Authors: Nair Malini , Meirmanov Serik 
Published: January 2025

Objective This article explores the views towards contextualizing Psychological First Aid (PFA) to address the specific needs of communities in Pacific Island Countries (PICs) impacted by disasters. The methodological approach involved a review of existing literature on PFA’s relevance, adaptation, and effectiveness in disaster response settings. Findings In disaster response, PFA is a recognized, evidence-informed psychosocial support activity internationally, yet measuring its effectiveness in real-time disasters remains challenging. Practical evaluation of evidence-based PFA requires a more strategic approach emphasizing localization and incorporating community participation and needs contextualization. This approach is essential to ensuring cultural relevance and acceptance within the diverse environments of the PICs. Conclusion A contextualized understanding of PFA can enhance its effectiveness and contribute to psychological resilience in communities marked by significant diversity and disaster vulnerability.
Pesticide Residues, Glyphosate Adsorption and Degradation Characteristics in Ethiopian Agricultural Soils
Authors: Ayenew Bereket , Getu Endalkachew 
Published: January 2025

Background: The decline in wheat output in Ethiopia is widely attributed to pests, which has led to a rise in the usage of pesticides to boost productivity. The degree of pesticides sorption and degradation which influence the likelihood of environmental contamination from pesticides seeping into water bodies from soil has not yet been published for Ethiopian soils. The study aimed at to quantify the levels of pesticide residues, assess glyphosate’s adsorption capabilities and degradation rate in the soils. Materials and methods: QuEChERS method of extraction was employed to determine the concentration of the respective pesticides. The adsorption capacities of glyphosate in agricultural soils of Cheha and Dinsho districts were measured using batch adsorption techniques. Results: Six pesticide residues were found in 12 soil samples at varied quantities. Glyphosate (24.00-219.31 µg kg−1), s-metolachlor (23.67-220.67 µg kg−1), chlorpyrifos (27.74 202.67 µg kg−1), pyroxulam (14.67-50.65 µg kg−1), florasulam (78.00-250.67 µg kg−1), malathion (15.00-49.67 µg kg−1). The experimental results showed that glyphosate was slightly sorbed at SD10 soil (18.91 μg−1−n mLn g−1) in comparison to SC1 soil (114.66 μg−1−n mLn g−1). Organic matter and clay content proving to be the principal factors influencing the process. According to adsorption experimental data, chemisorption is the major process in glyphosate adsorption, with the pseudo-second order kinetic model providing the best fit ( R2 = .99). The soils in the study area exhibit notable variations in glyphosate rate of degradation (0.0076-0.0221 week−1). The findings show that the main soil variables affecting the half-life (glyphosate degradation) were clay concentrations ( R2 = .48; P = .013), pH ( R2 = .55; P = .0055), Organic matter ( R2 = .74; P = .00027), Feox ( R2 = .50; P = .0105), and Alox ( R2 = .73; P = .00046). Conclusion: The weak glyphosate adsorption capabilities of soils can be a good indicator that the pesticide residues in the soil are poised to endanger soil organisms and contaminate nearby water bodies through runoff and leaching.
Botulinum Therapy for Pain Caused by Spasticity in Advanced Stages of Brain Tumor in Adolescents: A Case Report
Authors: Mano Tomoo , Murakami Toshiharu , Mori Haruki , Masuda Takashi 
Published: January 2025

Background: Spasticity is an upper motor neuron syndrome that exacerbates motor paralysis and is rarely associated with pain. This report elucidates the management of drug-resistant pain attributed to an adolescent brain tumor using botulinum therapy. Case presentation: A 15-year-old female patient experienced dizziness, developed muscle weakness in her upper extremities, and was diagnosed with diffuse glioblastoma of the pons. The tumor responded partially to radiation therapy. Three years later, at the time of recurrence, she had high muscle tone and pain in her extremities. On stimulation, her upper and lower extremities would bend and extend, respectively, causing excruciating pain. Despite experiencing pain-induced insomnia and restlessness, she was reluctant to use drugs, citing concerns about respiratory depression. She received botulinum therapy for her extremities 3 times (200, 300, and 500 U), with pain improvement after repeated treatments (Numerical rating scale from 7.5 to 1 and Short-form McGill Pain Questionnaire-2 score from 78 to 16). The effect lasted for more than three months after the final injection. Conclusion: Thus, botulinum therapy can potentially alleviate spasticity-associated pain in advanced stages of brain tumors in adolescents.
Unusual Presentation of Large Retroperitoneal Lipoma in a 3-Year-Old Child: A Case Report
Authors: Wubishet Mesfin , Shimelis Betre , Tigabie Workye , Lemma Ashenafi 
Published: January 2025

Background: Lipomas can occur almost anywhere in the body, but they are exceptionally rare in the retroperitoneal region. While lipomas are common in adults, they are quite uncommon in children. Even among adults, retroperitoneal lipomas are not frequently encountered. When symptomatic, retroperitoneal lipomas may present with abdominal swelling, pain, or constipation, as noted in previous literature. However, there have been no reported cases of retroperitoneal lipomas causing recurrent diarrhea in children. Case presentation: We present a rare case of a large retroperitoneal lipoma in a 3-year-old child who experienced recurrent diarrhea and intermittent abdominal pain for 2 months, without any urinary symptoms. All Laboratory investigations were within reference ranges for his age. A CT scan showed a large abdominal mass likely from the retroperitoneum, potentially a lipogenic tumor, though liposarcoma could not be excluded. The patient was successfully treated with complete surgical excision, and histopathological analysis confirmed the diagnosis of a benign lipoma. Conclusion: Retroperitoneal lipoma is a rare variant of lipoma in children, often presenting with various nonspecific and misleading symptoms. Due to the rarity of this condition and the limited awareness among clinicians, it frequently leads to misdiagnosis. Radiologic imaging, particularly CT and MRI scans, are essential diagnostic tools for identifying these tumors. This case report emphasizes the importance of maintaining a high index of suspicion for this rare condition when clinicians encounter recurrent diarrhea and concerning radiological findings. The characteristic behavior of retroperitoneal lipomas in children is still not well-defined; therefore, long-term follow-up is recommended.
An approach on sustainable leather production system and method: Chromium tanning in vacuum operated reaction vessel for sheepskins
Authors: Onem Ersin , Yorgancioglu Ali , Bitlisli Behzat Oral , Yilmaz Onur , Cavdar Ugur , Yilmaz Yalcin , Isbecer Alperen 
Published: January 2025

Conventional leather chromium tanning requires long process time, excessive water usage and results in low float exhaustion of chrome salts. Our study aimed to eliminate the negative aspects of chromium tanning by designing a vacuum operated reaction vessel/drum and suitable production recipe for sheepskins. Tanning time decreased from 10 h to 6 h under vacuum. Float uptake was increased almost 30% according to the chrome oxide (Cr2O3) contents in leather and residual floats. Using the process water was also considerably saved. Process success was proved with Cr2O3 contents in leather and wastewater by chemical analyses after tanning operations. Shrinkage temperature (Ts) controls as hydrothermal stability indicator of collagen were also realized on the tanned skins. Pollution loads of conventional and vacuum operated chromium tanning were discussed with chemical oxygen demand (COD), total suspended solids (TSS), conductivity and salinity in the tanning baths. Physico-mechanical properties were also compared of the final products by tensile strength and tear load analyses. The results showed that vacuum operated chromium tanning was highly effective and promised for the sustainable production of leather products.
Evaluating the Role of Professional Identity and Future Orientation in Enhancing Learning Engagement Among Special Education Majored Students: A Moderated Mediation Effect
Authors: Shaojie Tan 
Published: January 2025

This research delves into the intricate relationship between special education majored students’ perceptions of classroom atmosphere and their learning engagement, while also investigating the mediating influence of professional identity and the moderating effect of future orientation. A survey involving 582 special education majored students was conducted, utilizing the Student Perceived Class Atmosphere Scale, Learning Engagement Scale, College Students Professional Identity Scale, and Future Orientation Questionnaire for data collection. The collected data underwent thorough organization and statistical analysis using SPSS 24 software. The research results show that: (1) Special education majored students’ perception of class atmosphere has a positive predictive effect on learning engagement; (2) Professional identity plays an important mediating role between perception of class atmosphere and learning engagement; (3) Future orientation significantly moderates the direct path between special education majored students’ perceived class atmosphere and learning engagement, and moderated the second half of mediation models, the relationship between professional identity and special education majored students’ learning engagement. These research results enrich the theory of special education and have practical significance for improving the quality of special education teacher training.
Left ventricular disease as a risk factor for adverse outcomes and stroke recurrence in patients with embolic stroke of undetermined source
Authors: Cascio Rizzo Angelo , Schwarz Ghil , Bonelli Andrea , Magi Andrea , Agostoni Elio Clemente , Moreo Antonella , Sessa Maria 
Published: January 2025

Background: Severe left ventricular (LV) systolic dysfunction (ejection fraction [EF] < 30%) is a known cardiovascular risk factor and a major cause of cardioembolism. However, less severe forms of LV disease (LVD), such as mild-to-moderate LV dysfunction and LV wall motion abnormalities (LVWMAs), are considered potential minor cardiac sources in Embolic Stroke of Undetermined Source (ESUS), but their role is underexplored. This study aims to evaluate the prevalence of LVD in ESUS and its association with adverse vascular events and mortality. Methods: Retrospective, single-center study including consecutive ESUS patients admitted from January 2016 to May 2024. LVD was defined as either global systolic dysfunction (LV ejection fraction 30%–49%) or regional LVWMAs, unrelated to acute or recent (within 4 weeks) myocardial infarction. Univariate and multivariate Cox regression analyses evaluated the association of LVD with a primary composite outcome (including ischemic stroke recurrence, acute coronary events, and all-cause mortality), and its components separately. Results: Among the 556 ESUS patients (median age 71 years [IQR 60–80], 44.6% female), 95 (17.1%) had LVD, including 51 (53.7%) with reduced LVEF (30%–49%), and 81 (85.3%) presenting LVWMAs. During follow-up (median 30 months), LVD(+) patients had significantly higher rates of the composite outcome (41.0% vs 21.3%, p < 0.001), ischemic stroke recurrence (13.7% vs 5.9%, p = 0.007), acute coronary events (7.4% vs 2.4%, p = 0.012), and all-cause mortality (28.4% vs 15.2%, p = 0.002), compared to LVD(−) patients. Multivariate Cox regression analysis showed that LVD independently increased the risk of ischemic stroke recurrence (adjusted HR 2.13, 95%CI 1.08–4.24, p = 0.032) and the composite outcome (aHR 1.92, 95%CI 1.27–2.90, p = 0.002), but not acute coronary events (aHR 1.65; 95%CI 0.54–5.01, p = 0.374), or all-cause mortality (aHR 1.62; 95%CI 0.98–2.70, p = 0.062). Conclusions: LVD is significantly associated with an increased risk of ischemic stroke recurrence and adverse outcomes in ESUS patients. These findings highlight the clinical importance of identifying and optimizing LVD management among ESUS to improve long-term outcomes in this population.