bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coping strategies and associated factors among physically disabled people for psychological distress in Ethiopia
Authors: Tesfaw Getachew , Amare Tadele , Shumet Shegaye , Mirkina Yohannes , Kassew Tilahun , Abebaw Dessie , Salelew Endalamaw 
Published: July 2022

Abstract
Background: Coping strategies are frequently used among physically disabled people when they faced with adversities. In low- and middle-income countries are not investigated coping styles among psychological distress disabled individuals, despite a high prevalence of psychological distress. The aim of this study was to identify coping strategies of physically disabled people in Ethiopia to enhance the development of appropriate interventions. Methods: an institution-based cross-sectional study was employed among individuals at the University of Gondar staff and students living with physical disabilities from May to June 2021. All physically disabled staff and students were screened for psychological distress (n=269). The Brief Cope with Problems Experienced (COPE-28) was used to assess coping strategies for psychological distress. Results: In the present study, emotional-focused coping strategies are most frequently used when dealing with psychological distress among physically disabled participants. The most frequently used coping strategy was spirituality coping from emotional-focused subscales. In the multivariate analyses, urban residence and stigma were positively associated with emotion-focused coping strategies, and WHO quality of life (QOL) was positively associated with problem-focused coping sub-scale. Urban residence was negatively associated with dysfunctional coping strategy, but WHO QOL was positively correlated with dysfunctional coping sub-scale. Conclusions: In this study revealed that religion is the most frequently used coping strategy among the study participants. Urban residents, stigma, and WHO QOL were factors significantly correlated with a coping strategy. The Ministry of Education and Ministry of health may find the present findings useful for early detection, prevention, and interventions of coping strategies among physically disabled persons.
Crustal model of Lake Van Basin and Accurate Hypocentre Determination of 23 October Lake Van Earthquake (Mw:7.1) and Its Aftershocks
Authors: Akkoyunlu Mehveş Feyza , Kaypak Bülent , Oruç Bülent , Kalafat Doğan 
Published: July 2022

Abstract

We present a one-dimensional (1-D) velocity model of Lake Van basin and its surrounding and precise hypocenter locations by using 23 October 2011 (Mw = 7.1) Lake Van earthquake aftershock data, and the VELEST program which calculates 1-D minimum velocity model from body wave travel times together with station corrections. The study area covers a 180x90 km2 area centered at Lake Van. Ten new seismic stations were deployed after the 23 October 2011 Lake Van earthquake covering Lake Van region by Kandilli Earthquake Research Institute. After merging all available seismic station data in the region, we manually analyzed 7643 events that occurred from 23 October 2011 to 21 January 2015. We selected 1193 well-located events recorded by 16 stations with 48387 P- and 26913 S- arrival times for iterative simultaneous inversion of velocity and hypocenter parameters. During the inversion, near-surface velocity heterogeneity and station elevation influence were eliminated by station corrections. We computed Vp and Vp/Vs ratio of eight layers within 39 km depth with a 3 km thick sedimentary layer. Several tests were applied to ensure the stability of the velocity structure and accuracy of the aftershock locations. The aftershock sequence with the new 1-D velocity model was relocated and a drastic change was observed in the distribution whereas the new locations moved to the main shock area.
The Effect of Music on Working Memory Performance in noisy Simulated Open-Plan Offices
Authors: Kazemi Reza , Mohammadian Mostafa , Mollahoseini Sina , Smith Andy 
Published: July 2022

Abstract
The present study aimed to investigate the impact of music on working memory performance in noisy simulated open-plan offices. A simulated laboratory environment was prepared to evaluate the effect of music on individuals' working memory when exposed to irrelevant speech noise (ISN) conditions in open-plan office environments. Thirty students (15 females) aged 18–38 (M = 25.27, SD = 6.03) participated in the study. The participants' mental performance was evaluated when exposed to the ISN only and a combination of the ISN and music. The n-back working memory software was used to evaluate the individuals' working memory. The results indicated that the accuracy of individuals' responses to both simple and difficult tasks of n-back (n = 1, 2) significantly increased when music was played compared to the ISN only condition. However, there was no significant difference between conditions for reaction times in the working memory test. Using music is an easy and inexpensive intervention to increase work performance in open-plan office environments.
Pressure-area loop based phenotypic classification and mechanics of the esophagogastric junction physiology
Authors: Elisha Guy , Halder Sourav , Acharya Shashank , Carlson Dustin A. , Kou Wenjun , Kahrilas Peter J. , Pandolfino John E. , Patankar Neelesh A. 
Published: July 2022

Abstract
The esophagogastric junction (EGJ) is located at the distal end of the esophagus and acts as a valve allowing swallowed food to enter the stomach and preventing acid reflux. Irregular weakening or stiffening of the EGJ muscles results in changes to its opening and closing patterns which can progress into esophageal disorders. Therefore, understanding the physics of the opening and closing cycle of the EGJ can provide mechanistic insights into its function and can help identify the underlying conditions that cause its dysfunction. Using clinical functional lumen imaging probe (FLIP) data, we plotted the pressure-cross-sectional area loops at the EGJ location and distinguished two major loop types – a pressure dominant loop (PDL) and a tone dominant loop (TDL). In this study, we aimed to identify the key characteristics that define each loop type and determine what causes the inversion from one loop to another. To do so, the clinical observations are reproduced using 1D simulations of flow inside a FLIP device located in the esophagus, and the work done by the EGJ wall over time is calculated. This work is decomposed into active and passive components, which reveal the competing mechanisms that dictate the loop type. These mechanisms are esophagus stiffness, fluid viscosity, and the EGJ relaxation pattern.
Patterns of Child and Adolescent Psychiatric Admissions Before and After the Onset of the COVID-19 Pandemic: A Clinical Study from Istanbul
Authors: Ekinci Özalp , Adak İbrahim , Temel Gülhan , Taylan Gülser , Aydın Zeynep Ece , Gamlı İpek Süzer , Kocabaş Şükrücan , Boztepe Çağla , Karakoç Sevcan 
Published: July 2022

Abstract
Background
Very few studies compared the rates of child psychiatry diagnoses between the initial phase of the pandemic and the pre-pandemic records in clinical samples. This study from Istanbul aimed to compare the child and adolescent psychiatric admissions and diagnosis rates between the first three months of the pandemic, the previous three months in the same year and the same months in the previous year.
Methods
Children and adolescents were grouped according to the admission dates. Group A, between March 11 to June 1 2020; Group B, between January 1st to March 11 2020 and; Group C, between March 11 to June 1 2019. Only clinical interviews and diagnoses according to Kiddie Schedule for Affective Disorders and Schizophrenia-Present and Lifetime Version (K-SADS-PL) interview were included.
Results
The total number of admissions were n = 1052 for group A, n = 5792 for group B and n = 5800 for group C. In the group A; mean age of the sample was 11.21 ± 3.77 (%33 girls), while the same findings were 10.42 ± 3.91 (%34 girls) and 10.02 ± 3.87 (%33 girls) in group B and C, respectively. Regarding the diagnostic groups; Autism Spectrum Disorder (ASD), Obsessive Compulsive Disorder (OCD)/Tic Disorder and Intellectual Disability (ID) diagnoses were found to be higher in group A than group B and C (for ASD, 6.4%, 4.3% and 3.6%; for OCD/Tic Disorder 2.9%, 1.8%, 1.7%; for ID, 3.7%, 2.5%, 2.1%, respectively) (p < 0.001). Attention-Deficit Hyperactivity Disorder (ADHD) diagnosis was higher in group A than only group B (59.8%, 49.7%, respectively) (p < 0.001). Depression was higher in group A than only group C (4.1%, 2.2%, respectively) (p < 0.001). Conduct Disorder (CD) diagnosis was lower in group A than only group B (3.6%, 6.4%, respectively) (p < 0.005). The diagnoses of Adjustment Disorder (AD) and others (psychiatric problems apart from the aforementioned diagnoses) were lower in group A than group B and C (for AD, 0.7%, 3.1%, 3.4%; for others 3.3%, 12.6%, 9.6%, respectively) (p < 0.001).
Discussion
Child psychiatry diagnosis rates, and related healthcare needs, were found to change significantly during the inital phase of the pandemic period. Children and adolescents with neurodevelopmental disorders appear to be more affected than other diagnostic groups.
Clinical efficacy of different open approaches in the surgical treatment of thoracolumbar tuberculosis: A single-center retrospective comparative study
Authors: Wang Tianji , Lei Wei , Wu Zixiang , Xu Huifa , Ma Tiancheng , Ma Zhensheng , Li Tianqing 
Published: July 2022

Abstract
Objective
To assess the clinical efficacy of three different surgical approaches in the treatment of thoracolumbar tuberculosis.
Methods
138 patients with thoracolumbar tuberculosis treated by open surgery were retrospectively analyzed. The surgical methods were divided into anterior, posterior and anterior-posterior combined. The hospital stays, amount of bleeding, operative time, preoperative, postoperative and last follow-up ESR, CRP, Frankel score, ODI, VAS, correction and loss rate of kyphosis, fusion rate and complications were recorded and analyzed.
Results
The average follow-up was 66 months. The average hospital stay, operative time and amount of bleeding of anterior-posterior combined group were higher than other groups (P < 0.05). ESR and CRP of all patients were reduced postoperatively (P < 0.05). No significant difference among the three groups was found in the postoperative correction angle of kyphosis (P < 0.05), while the pre- and postoperative Cobb angle as well as correction rate had significant difference. The posterior approach could achieve better correction, ang the loss of correction was more in the anterior group, 40.9 percent of patients performed correction loss. The Frankel score, VAS and ODI were significantly reduced among three groups, and the incidence rate of complications of anterior approach was lower than the other groups, with significant difference (P < 0.05).
Conclusion
The anterior approach has more advantages and less complications, which is supposed to give preference to and could not be replaced by posterior and anterior-posterior combined approach.
miR-221-5p and miR-186-5p are the critical exosomal miRNAs in bladder cancer induced natural killer cells dysfunction
Authors: Huyan Ting , Li Mengjiao , Wang Chaochao , Chen Wenting , Zhou Xiaojie , Zhang Xuanshuo , Duan Suyang , Gao Shan , Li Qi 
Published: July 2022

Abstract
Bladder cancer (BC) is the 10th most commonly diagnosed cancer worldwide, its carcinogenesis mechanism has not been fully elucidated. BC is able to induce natural killer (NK) cells dysfunction and escape their immune surveillance. The present study found that exosome plays an important role in BC induced NK cell dysfunction by impairing viability, and inhibit the cytotoxicity of NK cell on target cells. Meanwhile, BC derived exosome inhibited the expression of important functional receptors NKG2D, NKp30, and CD226 on NK cells and the secretion of perforin and granzyme-B. Through high-throughput sequencing, the critical miRNAs with high expression in BC exosomes were identified. Furthermore, after Dual-Luciferase reporter assay and transfection experiment, miR-221-5p and miR-186-5p was confirmed can interfere the stability of mRNAs of DAP10, CD96, and perforin gene in NK cells and may be the potential targets using in the therapeutic application of BC.
Resectable Remnant Gastric Cancer: Worse Prognosis or Unsuitable Stage Classification System? A Retrospective Propensity Score Matching Analysis
Authors: Cui Hangtian , Yang Biao , Qin Jing , Lu Zhengmao , Fang Guoen , Xue Xuchao , Luo Tianhang 
Published: July 2022

Abstract
Purpose: Currently, the characteristics, and prognosis of remnant gastric cancer (RGC) were not fully understood yet. The present study aimed to describe the details of clinicopathological features of resectable RGC and investigated the factors affecting survival after the curative operation.Methods: From Jan. 2006 to Dec. 2015, a total of 118 resectable RGC patients (the RGC group) and 236 age-, sex- and TNM stages matched resectable gastric cancer (GC) patients (the control group) were recruited retrospectively. Clinicopathological characteristics and overall survival were compared between the two groups.Results: The overall survival rate was 46.61% for RGC patients compared to 55.08% for control groups (P < 0.01), and the mean overall survival time of RGC patients was 40.23 ± 32.27 months, compared with 55.06 ± 34.29 months in the control group (P = 0.023 after matching). The overall survival (OS) of RGC patients with stage IIb was much worse than IIa (P < 0.001) and similar to Ⅲa (P = 0.463) and Ⅲb (P = 0.014 ), which indicated that the current TNM classification was not suitable for the patients with RGC. Multivariate Cox proportional hazards model analysis revealed that TNM stage (HR: 3.899, P < 0.001) and metastatic lymph nodes ratio (LNR) (HR: 2.405, P = 0.028) were independent prognostic significance to OS.Conclusions: The OS of RGC was much worse than GC with similar TNM stages, which might be caused by an unsuitable TNM stage classification system for RGC. And LNR might consider a highly reliable indicator to evaluate the N status in RGC.
Scenario-based assessment of emergency management of urban infectious disease outbreaks
Authors: Yuan Pengwei , Liu Huifang , Shi Xiaoyi , Dong Xiaoqing 
Published: July 2022

Abstract

Infectious diseases pose a severe threat to human health and are accompanied by significant economic losses. Studies of urban outbreaks of infectious diseases are diverse. However, previous studies have neglected the issue of how to identify critical events and evaluate scenario-based modeling of urban infectious disease outbreak emergency management mechanisms. In this paper, we conduct an empirical analysis and scenario extrapolation using a questionnaire survey of 18 experts, based on the CIA-ISM method and scenario theory, to obtain the key factors influencing urban infectious disease outbreaks. Then, the effectiveness of the urban infectious disease outbreak emergency management mechanism is evaluated. Finally, the actual situation of COVID-19 in China is compared and verified, and the following conclusions and recommendations are drawn. (1) The scenario-based urban infectious disease emergency management model can be used to reproduce the development of urban infectious diseases. (2) The establishment of an emergency command center and the isolation and observation of people exposed to infectious diseases are the most critical key factors in the emergency management of urban outbreaks of infectious disease.
Sampling environmental DNA from trees and soil to detect cryptic arboreal mammals
Authors: Allen Michael C. , Kwait Robert , Vastano Anthony , Kisurin Alex , Zoccolo Isabelle , Jaffe Benjamin D. , Angle Jordan C. , Maslo Brooke , Lockwood Julie L. 
Published: July 2022

Abstract
Environmental DNA (eDNA) approaches to monitoring biodiversity in terrestrial environments have largely focused on sampling water bodies, potentially limiting the geographic and taxonomic scope of eDNA investigations. We assessed the performance of two strictly terrestrial eDNA sampling approaches to detect arboreal mammals, a guild with many threatened and poorly studied taxa worldwide, within two central New Jersey (USA) woodlands. We compared detection rates between two eDNA collection methods (tree bark vs. soil sampling), and two detection methods (qPCR vs. metabarcoding). Our survey, which included 94 sampling events at 21 trees, detected 16 species of mammals, representing over 60% of the diversity expected in the area. More DNA was found for the 8 arboreal vs. 8 non-arboreal species detected (mean: 2466 vs. 289 reads / sample). Tree bark sampling showed 1.8-3.0x higher detection probability than soil sampling among the 5 most common species (overall effect size: β = 1.39, 95% CI: [0.85, 1.91]). Comparing detection methods for big brown bat revealed 3.4x higher detection rates for qPCR over metabarcoding, illustrating the enhanced sensitivity of single-species approaches. Our results suggest that sampling eDNA from trees could serve as a useful new monitoring tool for cryptic arboreal mammal communities globally.
Less immune cell infiltration and worse prognosis for NSCLC patients with XPO1 copy number alterations
Authors: Li Xuanzong , Li Wanlong , Fan Xinyu , Zhang Dai , Wang Linlin 
Published: July 2022

Abstract
Background: Exportin 1 (XPO1) plays an important role in the maintenance of cellular homeostasis. However, the clinical implications of XPO1 alterations in non-small-cell lung cancer (NSCLC) patients are still unclear. Methods: We collected 5792 samples and 5644 patients with both mutation and CNA data from the cBioPortal database. The potential relationship between XPO1 alterations and survival of NSCLC patients was evaluated. Besides, we analyzed the tumor infiltration immune cells in patients with NSCLC harboring XPO1 CNA by TIMER database. Results: The total incidence of XPO1 alterations was 2.8 % (158/5644) in the entire NSCLC cohort, including 95 XPO1 CNA cases, 63 XPO1 mutation cases and one case coharboring XPO1 mutation and amplification. Our results showed that XPO1 CNA were more common in male NSCLC patients (p < 0.001). Importantly, XPO1 mutations were not associated with OS (p = 0.412), but XPO1 CNA was significantly associated with poor clinical outcomes of NSCLC patients (p < 0.001). Furthermore, we found that different categories of XPO1 CNA were associated with decreased immune cell infiltration in lung adenocarcinoma and lung squamous cell carcinoma. Conclusions: XPO1 CNA was correlated with several immune cell infiltration and significant poor clinical outcomes of NSCLC patients.
Analysis of the clinical effect of femoral neck system compared with three cannulated cancellous screws in the treatment of femoral neck fractures in young adults
Authors: Kuang Ximu , Jian Guojian , Chen Feixiong , Xie Desheng , Huang Yanpeng , Liu Haoyuan 
Published: July 2022

Abstract
Purpose To evaluate the effect of femoral neck system (FNS) internal fixation device compared with three cannulated screws (CCS) in the treatment of femoral neck fracture in young adults. Methods This retrospective study collected the data of 60 young adults with femoral neck fractures admitted to Chenggong Hospital Affiliated to Xiamen University from August 2020 to August 2021. They were divided into FNS group and CCS group according to the surgical method. Statistical methods were used to compare the operative and postoperative situation of two groups. Results Patients were followed up for 8 to 20 months. There was no statistically significant difference in the general baseline data, and they were comparable. The operation duration and operative blood loss and times of fluoroscopies in FNS group were greater than those of the CCS group（P＜0.05）；The partial and complete weight-bearing time and fracture healing time were earlier than those of the CCS group(P＜0.05). The Harris hip function score at 12 months postoperatively in FNS group (89.50±2.45) was greater than that in the CCS group (84.60±3.14)(P＜0.05); Overall complications rate (including nonunion, necrosis of the femoral head, internal fixation failure) occurred in the FNS group (3.3%) was lower than CCS (23.3%,P＜0.05).Conclusion FNS has both good biomechanical properties and relatively less invasiveness. FNS can effectively resist shear force, avoid further shortening of femoral neck and accelerate fracture healing. FNS is a reliable internal fixation device for femoral neck fractures in young adults.
A new method to identify the Position-Independent Geometric Errors in the Rotary axes of Five-axis Machine Tools
Authors: Osei Seth , Wang Wei , Qicheng Ding 
Published: July 2022

Abstract
Position-independent geometric errors (PIGEs), caused by assembly imperfection, affect the machine tool’s accuracy. Moreover, the rotary axes of five-axis machine tools introduce more PIGEs during parts machining, hence, the need to identify them to improve the accuracy. However, the identification of rotary axes centerlines and the use of extension bars, using double ball bar (DBB), introduce additional setup errors and uncertainties during error measurements and sometimes make the process tedious. This work proposes a new method to identify the eight (8) PIGEs in the rotary axes of a five-axis machine tool with a tilting table. The homogeneous transformation matrix (HTM) was used to construct the relative motion matrix to the established coordinate systems and then deduced the error model. Three different DBB installation setups were employed for the identification of the PIGEs in each rotary axis using the planar test, the recorded DBB length data was substituted into the model to obtain the PIGEs. The results show that the proposed PIGEs identification method is accurate and can improve the accuracy of the five-axis machine tool effectively, which shows a good improvement in the manufacturing industry.
Natural Convection of Williamson Nanofluid Over a Semi- Infinite Vertical Plate in the Presence of Radiation
Authors: LOGANATHAN P , SANGEETHA S 
Published: July 2022

Abstract
This paper analyzes a theoretical study of the effects of incompressible Williamson nanofluid flow over a semi-infinite vertical plate in the presence of radiation. The numerical solution of dimensionless partial differential equations is accomplished using the Crank-Nicholson finite difference method. The impact on fields of velocity and temperature of various types of non-dimensional prominence parameters, such as the Weissenberg number (We), Prandtl number (Pr), and radiation coefficient (R), is graphically illustrated and discussed. A discussion of fluid behavior in the form of isolines is provided. Velocity and temperature boundary layer thicknesses generally decrease as they move away from the vertical plate surface. However, the Williamson parameter appears to retard velocity and decrease temperature profiles near the surface. Moreover, smaller nanoparticles display uniform volume fractions, which reduces the variation in heat transfer rates.