bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the dynamics of extensions of free-abelian times free groups endomorphisms to the completion
Authors: Carvalho André 
Published: August 2022

AbstractWe obtain conditions of uniform continuity for endomorphisms of free-abelian times free groups for the product metric defined by taking the prefix metric in each component and establish an equivalence between uniform continuity for this metric and the preservation of a coarse-median, a concept recently introduced by Fioravanti. Considering the extension of an endomorphism to the completion, we count the number of orbits for the action of the subgroup of fixed points (respectively periodic) points on the set of infinite fixed (respectively periodic) points. Finally, we study the dynamics of infinite points: for automorphisms and some endomorphisms, defined in a precise way, fitting a classification given by Delgado and Ventura, we prove that every infinite point is either periodic or wandering, which implies that the dynamics is asymptotically periodic.
A person-centered approach to resilience and vulnerability in emerging adulthood: Predictions from parenting and personality in adolescence
Authors: de Maat Donna A. , Lucassen Nicole , Shiner Rebecca L. , Prinzie Peter 
Published: August 2022

AbstractIn this person-centered study, we identified different profiles of resilience and vulnerability in emerging adulthood in response to previously experienced stressful life events. Additionally, we examined whether mothers’ and fathers’ parenting and participants’ personality traits in adolescence predicted these profiles. Data from the Flemish Study on Parenting, Personality, and Development (N= 346 families) were used. At T1 (2004;Mage= 11 years), T2 (2007), and T3 (2009), mothers and fathers reported on their parenting and their child’s personality. At T4 (2018;Mage= 25 years), emerging adults retrospectively self-reported the occurrence and impact of 22 stressful life events and rated current behavior problems and subjective well-being. Latent profile analysis revealed three profiles: Competent (71%; low stress, low behavior problems, high subjective well-being), Vulnerable (21%; average stress, high behavior problems, low subjective well-being), and Resilient (9%; high stress, average behavior problems, average subjective well-being). Emerging adults in the Resilient profile had experienced higher levels of maternal positive parenting and were less emotionally stable and conscientious than those in the Competent profile. Furthermore, emerging adults in the Vulnerable profile were less emotionally stable than their peers in the Competent profile. These findings reveal new insights into the heterogeneous patterns of emerging adults’ adaptation following stressful life events.
The role of adolescent social relationships in promoting alcohol resistance: Interrupting the intergenerational transmission of alcohol misuse
Authors: Stephenson Mallory , Aliev Fazil , Kuo Sally I-Chun , Edwards Alexis C. , Pandey Gayathri , Su Jinni , Kamarajan Chella , Dick Danielle , Salvatore Jessica E. 
Published: August 2022

AbstractGenetic factors contribute to the intergenerational transmission of alcohol misuse, but not all individuals at high genetic risk develop problems. The present study examined adolescent relationships with parents, peers, and romantic partners as predictors of realized resistance, defined as high biological risk for disorder combined with a healthy outcome, to alcohol initiation, heavy episodic drinking, and alcohol use disorder (AUD). Data were from the Collaborative Study on the Genetics of Alcoholism (N = 1,858; 49.9% female; mean age at baseline = 13.91 years). Genetic risk, indexed using family history density and polygenic risk scores for alcohol problems and AUD, was used to define alcohol resistance. Adolescent predictors included parent-child relationship quality, parental monitoring, peer drinking, romantic partner drinking, and social competence. There was little support for the hypothesis that social relationship factors would promote alcohol resistance, with the exception that higher father-child relationship quality was associated with higher resistance to alcohol initiation (
$$\hat \beta $$
= −0.19, 95% CI = −0.35, −0.03). Unexpectedly, social competence was associated with lower resistance to heavy episodic drinking (
$$\hat \beta $$
= 0.10, 95% CI = 0.01, 0.20). This pattern of largely null effects underscores how little is known about resistance processes among those at high genetic risk for AUD.
Palliative care in pediatric patients with central nervous system cancer: Descriptive and comparative study
Authors: de Noriega Iñigo , Martino Alba Ricardo , Herrero Velasco Blanca , Madero López Luis , Lassaletta Álvaro 
Published: August 2022

AbstractObjectivesData regarding the palliative needs of pediatric patients with central nervous system (CNS) cancer are scarce. We aimed to describe the attention provided by a pediatric palliative care (PPC) team to patients with CNS cancer and the differences in care compared to patients who did not receive PPC.MethodThis retrospective study was based on the clinical records of deceased patients with CNS cancer attended by a PPC team over 10 years, analyzing their trajectory and provision of PPC, including medical, psychological, social, and nursing interventions. Furthermore, we compared the last month of life care of deceased patients with CNS cancer in the same institution, based on whether they were attended by the PPC team.ResultsOf 71 patients, 59 received PPC, with a median of 1.6 months (Interquartile range: 0.6–5.2) from referral to death. Home hospitalization was provided to 84.8%, nursing interventions were registered in 89.8%, psychological characteristics in 84.7%, and social interventions in 88.1%. The most common symptoms were pain, dyspnea, and constipation. When comparing patients from the same hospital who received PPC (n = 36) with those who did not (n = 12), the former spent fewer days in the hospital in their last month and last week (p < 0.01) and were more likely to die at home (50% vs. 0%; p < 0.01).Significance of resultsPatients with CNS cancer show various medical, social, and psychological needs during end-of-life care. Providing specific PPC interventions decreased the number of days spent at the hospital and increased the rate of death at home.
Extension and Evaluation of University of Washington Moist Turbulence Scheme to Gray‐Zone Scales
Authors: Wei Wei , Peng Xindong , Lin Yanluan , Li Jianduo , Zhang Guo , Yang Yang , Long Jingchao 
Published: August 2022

AbstractWith the rapid improvement in computational resources, it has become possible to structure numerical weather model simulations to use sub‐kilometer grid spacing. Traditional turbulence‐mixing closures have become obsolete within the context of the gray zone of turbulence. Here, a new scale‐aware algorithm (SA‐UW) is developed based on the UW (University of Washington Moist Turbulence) scheme. By dividing both the local and nonlocal vertical turbulence flux into sub‐grid and resolved parts, the partition of sub‐grid turbulence is tuned by a set of well‐acknowledged scale‐dependent relationships. Idealized simulations confirm that the newly developed scheme can adequately reproduce sub‐grid turbulence transport at gray‐zone scales. The inclusion of a nonlocal transport term in the SA‐UW scheme is essential, as it vastly improves the distribution and intensity of coherent structures. The SA‐UW scheme recovers the conventional UW scheme when grid spacing is larger than the turbulence length scale, thereby evincing the sale‐aware capability of the new method. For real‐case simulations, the SA‐UW scheme can capture the diurnal cycle and provide a more accurate vertical structure of temperature and humidity.
Soil CO2 Controls Short‐Term Variation but Climate Regulates Long‐Term Mean of Riverine Inorganic Carbon
Authors: Stewart Bryn , Zhi Wei , Sadayappan Kayalvizhi , Sterle Gary , Harpold Adrian , Li Li 
Published: August 2022

AbstractThe evasion of CO2 from inland waters, a major carbon source to the atmosphere, depends on dissolved inorganic carbon (DIC) concentrations. Our understanding of DIC dynamics across gradients of climate, geology, and vegetation conditions however have remained elusive. To understand its large‐scale patterns and drivers, we collated instantaneous and mean (multiyear average) DIC concentrations from about 100 rivers draining minimally‐impacted watersheds in the contiguous United States. Within individual sites, instantaneous concentrations (C) measured at daily to seasonal scales exhibit a near‐universal response to changes in river discharge (Q) in a negative power law form. High concentrations occur at low discharge when DIC‐enriched groundwater dominates river discharge; low concentrations occur under high flow when relatively DIC‐poor shallow soil water predominates river discharge. Such patterns echo the widely observed increase of soil CO2 and DIC with depth and the shallow‐and‐deep hypothesis that emphasizes the importance of flow paths and source water chemistry. Across sites, mean concentrations (Cm) decrease with increasing mean discharge (Qm), a long‐term climate measure, and reachs maxima at around 200 mm/yr. A parsimonious model reveals that high mean DIC arises from soil CO2 accumulation when rates of DIC‐generating reactions are relatively high compared to its export fluxes in arid climates. Although instantaneous and mean DIC concentrations similarly decrease with increasing discharge, results here highlight their distinct drivers: daily to seasonal‐scale instantaneous concentration variations (C) are controlled by subsurface CO2 distribution over depth (from below), whereas long‐term mean concentrations (Cm) are regulated by climate (from above). The results emphasize the significance of land‐river connectivity via subsurface flow paths. They also underscore the importance of characterizing subsurface CO2 distribution to illuminate belowground processes in order to project the future of water and carbon cycles in a warming climate.
Occurrence and Distribution Patterns of Magnetic Particles Within Stalagmite Growth Laminae
Authors: Shi Taiheng , Ding Jianyv , Zhu Zongmin , Zhang Hongbin , Huang Junhua 
Published: August 2022

AbstractThe concentrations of magnetic particles in stalagmites depend greatly on the regional hydrologic condition, and thus can act as an important proxy for paleoclimate reconstruction. The central axis region of a stalagmite is usually selected for such magnetism study. However, little is known about the distribution and influence factors of exogenetic magnetic particles within the growth laminae. In this study, the occurrence and variations of magnetic particles along the growth laminae of three shape stalagmites were investigated by a set of magnetic measurements, including isothermal remanent magnetization (IRM) acquisition curves and low‐temperature magnetic analysis. The results show the main magnetic remanence carrier is detrital magnetite/maghemite, coexisting with small amounts of hematite and goethite. The distribution of soft magnetic particles along the growth laminae showed different patterns among the three shape stalagmites (dome, cone, and candle). For the dome shape stalagmite, the soft magnetic particle concentrations in all studied growth layers showed an increasing trend from center to edge. Similar patterns were also appeared in the bottom growth layers of the cone and candle shape stalagmites. This edge enrichment of magnetic particles is caused by drip water washing effect. However, such enrichment pattern became weaker or even inverse in the top growth layers of the cone and candle shape stalagmites, indicating that the shapes of stalagmites could also affect the surface distribution of soft magnetic minerals. These uneven distributions of magnetic particles imply that the central axis region of a stalagmite may not always be the optimal specimen for environmental magnetism study.
Trans-genetic effects of circular RNA expression quantitative trait loci and potential causal mechanisms in autism
Authors: Mai Te-Lun , Chen Chia-Ying , Chen Yu-Chen , Chiang Tai-Wei , Chuang Trees-Juen 
Published: August 2022

AbstractGenetic risk variants and transcriptional expression changes in autism spectrum disorder (ASD) were widely investigated, but their causal relationship remains largely unknown. Circular RNAs (circRNAs) are abundant in brain and often serve as upstream regulators of mRNAs. By integrating RNA-sequencing with genotype data from autistic brains, we assessed expression quantitative trait loci of circRNAs (circQTLs) that cis-regulated expression of nearby circRNAs and trans-regulated expression of distant genes (trans-eGenes) simultaneously. We thus identified 3619 circQTLs that were also trans-eQTLs and constructed 19,804 circQTL-circRNA-trans-eGene regulatory axes. We conducted two different types of approaches, mediation and partial correlation tests (MPT), to determine the axes with mediation effects of circQTLs on trans-eGene expression through circRNA expression. We showed that the mediation effects of the circQTLs (trans-eQTLs) on circRNA expression were positively correlated with the magnitude of circRNA-trans-eGene correlation of expression profile. The positive correlation became more significant after adjustment for the circQTLs. Of the 19,804 axes, 8103 passed MPT. Meanwhile, we performed causal inference test (CIT) and identified 2070 circQTL-trans-eGene-ASD diagnosis propagation paths. We showed that the CIT-passing genes were significantly enriched for ASD risk genes, genes encoding postsynaptic density proteins, and other ASD-relevant genes, supporting the relevance of the CIT-passing genes to ASD pathophysiology. Integration of MPT- and CIT-passing axes further constructed 352 circQTL-circRNA-trans-eGene-ASD diagnosis propagation paths, wherein the circRNA-trans-eGene axes may act as causal mediators for the circQTL-ASD diagnosis associations. These analyses were also successfully applied to an independent dataset from schizophrenia brains. Collectively, this study provided the first framework for systematically investigating trans-genetic effects of circQTLs and inferring the corresponding causal relations in diseases. The identified circQTL-circRNA-trans-eGene regulatory interactions, particularly the internal modules that were previously implicated in the examined disorders, also provided a helpful dataset for further investigating causative biology and cryptic regulatory mechanisms underlying the neuropsychiatric diseases.
The design of a novel arthroscopy shaver
Authors: Gu Xuelian , Yuan Shiting , Xu Pengju , Xiao Shanshe , Liu Wentao , Lai Weiguo , Chen Zhi , Liang Peng , Zhao Gaiping 
Published: August 2022

AbstractCases of arthroscopic surgery have increased over the past two decades, and arthroscopic shaver systems have become a commonly used orthopedic tool. Nevertheless, most shavers generally have problems such as the cutting edge is not sharp enough and easy to wear. This paper aims to discuss the structural characteristics of BJKMC’s (Bojin◊ Kinetic Medical) novel arthroscopic shaver, the double serrated blade. The product's design and verification process are outlined. BJKMC’s articular arthroscopy shaver has a “tube in a tube” structure, comprising a stainless steel outer sleeve and a rotating hollow inner tube. The outer sleeve and inner tube have corresponding suction and cutting windows, and there are serrated teeth on the inner and outer casing. To verify the design rationality, it was compared to Dyonics◊’s equivalent product, the Incisor◊ Plus Blade. The appearance, cutting tool hardness, metal pipe roughness, cutting tool wall thickness, tooth profile, and angle, overall structure, and the key dimensions were examined and compared. Compared with Dyonics◊’s Incisor◊ Plus Blade, BJKMC’s Double Serrated Blade had a smoother working surface, harder and thinner blade head. Therefore, BJKMC’s product may have satisfactory performance when it comes to surgery.
Role of Keap1-Nrf2/ARE signal transduction pathway in protection of dexmedetomidine preconditioning against myocardial ischemia/reperfusion injury
Authors: Li Hui-xian , Wang Tai-hang , Wu Lin-xin , Xue Fu-shan , Zhang Guo-hua , Yan Tao 
Published: August 2022

Abstract
Objective: To explore the role and mechanism of the Kelch sample related protein-1-nuclear factor erythroid-2 related factor 2/antioxidant response element (Keap1-Nrf2/ARE) signaling pathway in protection of dexmedetomidine (DEX) preconditioning against myocardial ischemia/reperfusion injury (MIRI). Methods: A total of 70 male SD rats were randomly divided into seven equal groups (n=10): blank control (S group), ischemia/reperfusion injury (C group), DEX preconditioning (DEX group), tertiary butylhydroquinone (tBHQ) control (tBHQ group), combined tBHQ and DEX preconditioning (tBHQ+DEX group), all-trans retinoic acid (ATRA) control (ATRA group), and combined ATRA and DEX preconditioning (ATRA+DEX group). Serum creatine kinase-MB (CK-MB) and cardiac troponin I (cTnI) concentrations were measured by ELISA kits, and the infarct size (IS) was assessed by Evan’s blue and 2,3,5-triphenyltetrazolium chloride (TTC) staining. Oxidative stress was assessed through Western blotting for expression of Keap1-Nrf2/ARE pathway members and oxidative stress markers. Results: Cardioprotection of DEX, tBHQ, and tBHQ+DEX preconditioning treatments were shown as lower concentrations of serum CK-MB and cTnI and a smaller IS following MIRI in rats compared with those of MIRI rats without pre-treatment. In addition, tBHQ+DEX preconditioning exhibited stronger myocardial protection compared with DEX preconditioning. Mechanistically, the cardioprotection offered by DEX, tBHQ, and tBHQ+DEX preconditioning treatments was mediated via exerting antioxidant stress through activation of the Keap1-Nrf2/ARE signal transduction pathway. Conversely, the protective effects of DEX were diminished by blocking the Keap1-Nrf2/ARE pathway with inhibitor ATRA. Conclusion: DEX preconditioning protects against MIRI by exerting antioxidant stress through activation of the Keap1-Nrf2/ARE signal transduction pathway, while inhibition of the Keap1-Nrf2/ARE signal transduction pathway reverses the protective effect of DEX preconditioning on MIRI.
Paramagnetic probes in an organic semiconductor: μSR and DFT calculations of the Mu adducts of Alq3 and 8-hydroxyquinoline
Authors: McKenzie Iain , Cannon Joseph , Cordoni-Jordan Danaan , Mulley Brian P. , Scheuermann Robert 
Published: August 2022

It has been claimed that longitudinal field muon spin relaxation (LF-μSR) experiments on the organic semiconductor (OSC) tris-(8-hydroxyquinoline)aluminum(III) (Alq3) have measured electron hopping rates of ∼1012s−1, while density functional theory (DFT) calculations suggest that electron hopping between a muoniated radical and a neighboring molecule is energetically unfavorable and that the LF-μSR experiments were probing muoniated radicals with localized spin density. We have performed avoided level crossing muon spin resonance (ALC-μSR) and transverse field muon spin rotation (TF-μSR) measurements on Alq3 and 8-hydroxyquinoline (8hq), which is meant to model the muoniated radicals present in Alq3 when they are not in an OSC. These are supplemented by benchmarked DFT calculations. The ALC-μSR and TF-μSR spectra of 8hq and Alq3 are best explained by Mu adding to all six secondary carbons of the quinolate rings with roughly equal yields and localized spin density. There is no evidence in the TF-μSR spectrum of Alq3 for the formation of radicals with muon hyperfine coupling constants of 23 or 91 MHz as reported earlier by others. Our measurements support the view that there is localized spin density on the molecule to which Mu is covalently bound and the muon is not a passive probe in organic systems as it can be incorporated into radicals that have different electronic structures to the parent compounds. The muoniated radicals in Alq3 are more short-lived than in 8hq, which could be due to interactions with mobile electrons in the OSC, but with electron spin flip rates on the order of ∼107s−1.
Individual differences in identifying creative metaphors from video Ads
Authors: Pan Molly Xie , Tay Dennis 
Published: August 2022

Abstract
Reliable identification of metaphors from multimodal discourse has attracted scholarly attention in recent years. However, the role of individual differences in identifying creative metaphors from video ads is underexplored from an empirical perspective. This includes the extent to which individual differences influence metaphor identification in multimodal discourse and how the individual differences result in divergent identification. Our study contributes to addressing these issues by investigating how the background of researching metaphors influences identifying creative metaphors from video ads. We compared results of creative metaphor identification from three metaphor analysts and three external annotators who were novice to metaphor research and probed into the underlying reasons for divergent identification through discussions among six annotators. Both groups of annotators applied Creative Metaphor Identification Procedure for Video Advertisements (C-MIPVA) (Pan & Tay, 2021) into the same 20 Chinese video ads through a systematic process of inter-rater reliability examinations. Results from Fleiss’ Kappa and Percentage Agreement provided substantial support for reliable identification, regardless of the metaphor research background. Discussions among annotators revealed that the interplay between the individual differences in life experience and the influences of temporal and dynamic discourse lead to extra identification, different content, and missing cases of metaphors.
Comment on ‘Thermodynamic relations and ro-vibrational energy levels of the improved Pöschl–Teller oscillator for diatomic molecules’
Authors: Yanar Hilmi 
Published: August 2022

Abstract
In this comment, it is shown that the vibrational energies of the X
1Σ+ state of the RbH molecule via improved generalized Pöschl–Teller potential reported by Eyube et al (2021 J. Phys. B: At. Mol. Opt. Phys.
54 155102) are calculated incorrectly. Accurate calculations are given in the present study.
Low power implementation of high frequency SiPM readout for Cherenkov and scintillation detectors in TOF-PET
Authors: Cates Joshua W , Choong Woon-Seng 
Published: August 2022

Abstract
State-of-the-art (SoA) electronic readout for silicon photomultiplier (SiPM)-based scintillation detectors that demonstrate experimental limits in achievable coincidence time resolution (CTR) leverage low noise, high frequency signal processing to facilitate a single photon time response that is near the limit of the SiPMs architecture. This readout strategy can optimally exploit fast luminescence and prompt photon populations, and promising measurements show detector concepts employing this readout can greatly advance PET detector CTR, relative to SoA in clinical systems. However, the technique employs power hungry components which make the electronics chain impractical for channel-dense time-of-flight (TOF)-PET detectors. We have developed and tested a low noise and high frequency readout circuit which is performant at low power and consists of discrete elements with small footprints, making it feasible for integration into TOF-PET detector prototypes. A 3 × 3 mm2 Broadcom SiPM with this readout chain exhibited sub-100 ps single photon time resolution at 10 mW of power consumption, with a relatively minor performance degradation to 120 ± 2 ps FWHM at 5 mW. CTR measurements with 3 × 3 × 20 mm3 LYSO and fast LGSO scintillators demonstrated 127 ± 3 ps and 113 ± 2 ps FWHM at optimal power operation and 133 ± 2 ps and 121 ± 3 ps CTR at 5 mW. BGO crystals 3 × 3 × 20 mm3 in size show 271 ± 5 ps FWHM CTR (1174 ± 14 ps full-width-at-tenth-maximum (FWTM)) at optimal power dissipation and 289 ± 8 ps (1296 ± 33 ps FWTM) at 5 mW. The compact and low power readout topology that achieves this performance thereby offers a platform to greatly advance PET system CTR and also opportunities to provide high performance TOF-PET at reduced material cost.