bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH CELAH CAMSHAFT TERHADAP NOISE PADA CYLINDER HEAD HONDA CB 150 R
Authors: Hasan Indra , Denur  
Published: January 2022

Noise on a motorcycle is unwanted sound because it does not fit the context of space and time thus affecting ride comfort . Noise caused by the vibrating object or objects collide . Which became the main object causes of noise in the Cylinder Head Honda cb 150 R is due to the large gap camshaft causing collision between the camshaft with holder.
This research was conducted entirely in the workshop by examining the influence of several variations of the gap camshaft to noise generated in the cylinder head . Variations slit used was 0,75 mm , 0,85 mm , 0,95 mm , 1,05 mm, and 1,15 mm . The results showed that the variation of the gap camshaft significant effect on the noise generated , namely : a gap of 0,75 mm camshaft generate noise by 78,12 dB , 0,85 mm gap camshaft generate noise with a value of 78,37 dB , 0,95 mm gap camshaft generate noise 78,93 dB , 1,05 mm gap camshaft generate noise levels at 79,95 dB, and 1,15 mm gap camshafts produce 80,23 dB.
Based on the results of the research with camshaft gap variation can be concluded that the lowest noise level generated by the camshaft gap of 0,75 mm .
Obstacles sur le chemin de la psychothérapie pour les personnes âgées dépressives : un modèle d’accès en plusieurs phases
Authors: Falk Katrin , Kammerer Kerstin 
Published: January 2022

Les maladies dépressives sont aussi répandues en Allemagne parmi les plus de 65 ans que parmi les populations plus jeunes, mais les personnes âgées font beaucoup plus rarement appel à un traitement psychothérapeutique que leurs cadets. L’étude Psychotherapie im Alter – Barrieren und Möglichkeiten des Zugangs (PSYTIA, « Psychothérapie et troisième âge – obstacles et possibilités d’accès ») examine, en Allemagne, à l’aide de méthodes de recherche qualitatives et quantitatives, quels sont les obstacles qui font hésiter les populations âgées atteintes d’une maladie dépressive à s’engager sur le chemin de la psychothérapie, et quelles sont les possibilités d’accès. Sur la base d’entretiens semi-directifs avec des personnes âgées dépressives (n = 18), des médecins généralistes (n = 14) et des psychothérapeutes (n = 11) de Berlin, nous avons reconstitué les étapes de l’accès à la psychothérapie dans son aspect social, un processus dans lequel différents acteurs jouent un rôle, chacun avec sa perception et sa conception propres. On peut distinguer quatre phases dans ce processus : 1. Le ou la patient(e) a besoin d’explications et de recevoir de l’aide (trouver un remède) ; 2. Il/elle envisage une psychothérapie ; 3. Il/elle cherche un psychothérapeute ; 4. Il/elle développe une relation psychothérapeutique bénéfique. La présente contribution révèle, pour chacune de ces phases, quels obstacles se dressent, quelles possibilités existent, et l’importance que cela revêt dans la décision des personnes âgées dépressives de faire appel à un traitement psychothérapeutique. Les résultats montrent qu’il est possible de faciliter l’accès de cette tranche d’âge à un traitement psychothérapeutique, tant à travers l’organisation générale qu’à travers le rôle de chacun des acteurs.
THERMAL PERFORMANCE OF FELT TYPE VEGETATED FACADE SYSTEMS IN A TEMPERATE CLIMATE DURING HEATING AND COOLING PERIODS
Authors: Yüksel Elif Özer , Türkeri Nil 
Published: January 2022

ABSTRACT
Using vegetated facade systems (VFS) as a sustainable solution for existing and new buildings and evaluating thermal performance of these sytems are not a new concept. However, there is a gap in literature about measuring thermal performance of VFS applied on an insulated wall. Also, in the research literature, there are few studies measuring thermal performance of felt type VFS in temperate climates, and data about the thermal performance of VFS during winter periods is still scarce. Thus, the aim of the present study is to measure the thermal performance of a felt type VFS applied on a thermal insulated existing wall that us located in Kocaeli, Turkey, under Csa climate conditions during heating and cooling periods. Test results indicate that the felt type VFS acts as a shading device and has a positive contribution to the thermal performance of building walls during a cooling period. In daytime when there is a high amount of solar radiation, felt type VFS decreased exterior surface temperatures of the insulated existing wall by a maximum of 24.4°C, 32.2°C and 37.2°C, in spring, summer and fall periods, respectively. Additionally, indoor air temperatures of the vegetated facade were lower than indoor air temperatures of the reference facade with the maximum difference of 1.8°C during the cooling period. Also, test results indicate that the vegetated facade never dropped to below 0°C while exterior surface temperatures of the reference facade dropped below 0°C at nighttime in the winter period. Thus, it can be claimed that the felt type VFS behaves as a thermal buffer and enhances the thermal performance of the exterior wall of the existing building during heating periods at nighttime. As a conclusion, although differences between exterior surface temperatures of vegetated and reference walls were high, differences between interior surface temperatures of vegetated and reference walls were not meaningful. That is due to the fact that the existing building exterior wall assembly includes 5 cm thickness thermal insulation material which enhance the thermal performance of the brick wall. Finally, according to solar reflectance results, it can be claimed that vegetated facade systems have a positive effect on reducing urban heat island effect.
EXPERIMENTAL STUDY OF ACOUSTICAL INSULATION OF CEMENT-BASED BOARD PREPARED WITH WASTE COCONUT COIR AND OIL PALM FIBERS
Authors: Lertwattanaruk Pusit , Makul Natt , Masuwan Kanokwan 
Published: January 2022

ABSTRACT
Among the major challenges facing the modern era of technological and industrial advancements are pollution and exponentially growing energy consumption. Pollution continues to be a menace affecting different aspects of life such as health, productivity, and comfort. This paper focuses on the elimination or reduction of sound pollution in buildings using cement-based boards made from pretreated coconut coir and oil palm fibers obtained from agricultural residues. The study includes an account of the preparation of fiber cement boards made from Portland cement Type 1, limestone powder, water, sand, and pretreated coconut coir and oil palm fibers at 5, 10, 15, and 20% by weight of powder materials, respectively, and a high-range water reducer in order to make sure that the natural materials would be spread in an even way throughout the specimens. Sound insulation tests were performed as key indicators of the performance of the fiber cement boards. It was found that an increase in the proportion of natural materials resulted in fiber cement boards with decreased density, compressive strength, and flexural strength. Furthermore, in relation to both physical and mechanical performance, the boards incorporating coconut fibers were superior to those incorporating oil palm fibers. With an increased proportion of natural fibers, sound insulation performance tended to improve. The boards prepared with coconut coir and oil palm fibers in this study yielded acceptable physical and mechanical properties and showed promise in relation to providing insulative protection against sound.
Single-Cell–Based High-Throughput Ig and TCR Repertoire Sequencing Analysis in Rhesus Macaques
Authors: Walsh Evan S , Tollison Tammy S , Brochu Hayden N , Shaw Brian I , Diveley Kayleigh R , Chou Hsuan , Law Lynn , Kirk Allan D , Gale Michael , Peng Xinxia 
Published: January 2022

Abstract
Recent advancements in microfluidics and high-throughput sequencing technologies have enabled recovery of paired H and L chains of Igs and VDJ and VJ chains of TCRs from thousands of single cells simultaneously in humans and mice. Despite rhesus macaques being one of the most well-studied model organisms for the human adaptive immune response, high-throughput single-cell immune repertoire sequencing assays are not yet available due to the complexity of these polyclonal receptors. We used custom primers that capture all known rhesus macaque Ig and TCR isotypes and chains that are fully compatible with a commercial solution for single-cell immune repertoire profiling. Using these rhesus-specific assays, we sequenced Ig and TCR repertoires in &gt;60,000 cells from cryopreserved rhesus PBMCs, splenocytes, and FACS-sorted B and T cells. We were able to recover every Ig isotype and TCR chain, measure clonal expansion in proliferating T cells, and pair Ig and TCR repertoires with gene expression profiles of the same single cells. Our results establish the ability to perform high-throughput immune repertoire analysis in rhesus macaques at the single-cell level.
Comprehensive Immune Profiling Reveals CD56+ Monocytes and CD31+ Endothelial Cells Are Increased in Severe COVID-19 Disease
Authors: Dutt Taru S , LaVergne Stephanie M , Webb Tracy L , Baxter Bridget A , Stromberg Sophia , McFann Kim , Berry Kailey , Tipton Madison , Alnachoukati Omar , Zier Linda , Ebel Greg , Dunn Julie , Henao-Tamayo Marcela , Ryan Elizabeth P 
Published: January 2022

Abstract
Immune response dysregulation plays a key role in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogenesis. In this study, we evaluated immune and endothelial blood cell profiles of patients with coronavirus disease 2019 (COVID-19) to determine critical differences between those with mild, moderate, or severe COVID-19 using spectral flow cytometry. We examined a suite of immune phenotypes, including monocytes, T cells, NK cells, B cells, endothelial cells, and neutrophils, alongside surface and intracellular markers of activation. Our results showed progressive lymphopenia and depletion of T cell subsets (CD3+, CD4+, and CD8+) in patients with severe disease and a significant increase in the CD56+CD14+Ki67+IFN-γ+ monocyte population in patients with moderate and severe COVID-19 that has not been previously described. Enhanced circulating endothelial cells (CD45−CD31+CD34+CD146+), circulating endothelial progenitors (CD45−CD31+CD34+/−CD146−), and neutrophils (CD11b+CD66b+) were coevaluated for COVID-19 severity. Spearman correlation analysis demonstrated the synergism among age, obesity, and hypertension with upregulated CD56+ monocytes, endothelial cells, and decreased T cells that lead to severe outcomes of SARS-CoV-2 infection. Circulating monocytes and endothelial cells may represent important cellular markers for monitoring postacute sequelae and impacts of SARS-CoV-2 infection during convalescence and for their role in immune host defense in high-risk adults after vaccination.
The public-private partnership (PPP) initiative in healthcare system: as the pathways to achieve the SDGs in Nepal
Authors: Bhatt Laxman Datt , Shrestha Ramesh , Bhandari Ved Prasad 
Published: January 2022

Globally, financing healthcare is one of the biggest challenges and it becomes a life or death issue in poor countries. Nepal is strongly committed to universal health coverage and Sustainable Development Goals. Existing public health services are inadequate to cater to the growing demands of quality health care and Public Private Partnership (PPP) evolved as newer arrangement for robust healthcare system, improved healthcare quality and enhance cost-effectiveness. Nepal has successfully utilized the PPP model in multiple sectors, however there is limited experience in healthcare. Strengthening PPP models in healthcare could be the pathway for Nepal toward SDG’s and UHC achievement.
Factors Predicting Spiritual Well-Being among Dependent Older People
Authors: Trapsinsaree Doungmon , Pothiban Linchong , Chintanawat Rojanee , Wonghongkul Tipaporn 
Published: January 2022

Spiritual well-being is a deep feeling within the mind that represents peacefulness and the inner strength of individuals, resulting from an understanding of the nature of life and acceptance of changes occurring to themselves. Spiritual well-being is; therefore, very important to dependent older people. The objectives of this study were to identify the levels of spiritual well-being of dependent older people, to examine the relationships between religious belief, religious practice, self-esteem, social support, depression, and spiritual well-being, and to examine the ability of those factors to predict spiritual well-being among dependent older people. The study sample were 395 of people aged 60 years and above who are dependent and live in three provinces in southern Thailand. Data were collected using questionnaires, including the Spiritual Well-Being Scale for Dependent Older People, Thai version of the Rosenberg Self-Esteem Scale, Thai version of the Multidimensional Scale of Perceived Social Support, Thai Geriatric Depression Scale, the Religious Practices Questionnaire, and the Buddhist Belief Questionnaire. Data were analyzed using descriptive statistics, Spearman’s rank correlation coefficient, and multiple regression analysis. The study results were as follows: 1) The spiritual well-being among dependent older people was at a moderate level (x̅ = 46.97, SD = 7.22). 2) Religious belief, religious practice, self-esteem, and social support significantly related positively to spiritual well-being (p < 0.01), while depression significantly related negatively to spiritual well-being (p < 0.01). 3) Religious belief, self-esteem, and social support together could explain 46.00 % of the variance in spiritual well-being. The results of this study can be used by nurses and health care providers to determine interventions for enhancing spiritual well-being in this particular group of older people.
HIGHLIGHTS

Spiritual well-being is one of the important dimensions of holistic care. Spiritual well-being has a positive effect on physical, mental and social health
The conceptual framework is guided by the Buddhism Principles
Religious belief, self-esteem, and social support together could explain 46.00 % of the variance in spiritual well-being
Prevalence of osteopenia and osteoporosis among the population of southern Kyrgyzstan - A cross-sectional observational study
Authors: Tagaev Tugolbai , Imanalieva Farida , Mamatov Sagynali , Vityala Yethindra , Zhumabekova Altynai 
Published: January 2022

Introduction and Aim: Osteoporosis is a skeletal disorder characterized by diminished bone strength that increases the risk of fracture in instances of trivial trauma. The objective was to conduct ultrasound bone densitometry in different age groups (18-60 years and older) in southern Kyrgyzstan, to identify and study the prevalence of osteopenia and osteoporosis.

Materials and Methods: In this cross-sectional observational study a total of 1200 participants were included, where 580 men and 620 women were aged between 18-60 years and older. Based on the age, the participants were divided into three groups. Bone mineral density in participants was measured using a SONOST-3000 densitometer model. The study was conducted among the population of the Osh and Jalal-Abad regions.

Results: Among the population of Osh state in the first group, normal values were found in 65.0%, osteopenia in 26.0%, and osteoporosis in 9.0% of participants. In the second group, values were significantly higher than in the first group. In the third age group, values exceeded significantly compared to the first and second groups. Similar data were obtained from the population of Jalal-Abad state, but a significant difference was found in the elderly people group with a higher percentage of osteopenia and osteoporosis.

Conclusion: The results showed the prevalence of osteopenia and osteoporosis in participants of different age categories of Osh and Jalal-Abad states, and especially in the elderly. Depending on the gender distribution, the prevalence of osteopenia and osteoporosis in our study is significantly higher in women than in men.
Nutrigenetics and nutrigenomics: A brief review with future prospects
Authors: Bahinipati Jyotirmayee , Sarangi Rajlaxmi , Mishra Sanjukta , Mahapatra Srikrushna 
Published: January 2022

Individual’s genetic makeup best describes the properties regarding its growth and development. It is stored and passed on to generations and is in dynamic equilibrium with the environmental and other non-living factors. The most predominant environmental stimuli are diet/nutrition. Diet/nutrition interacts and modulates varying underlying molecular mechanisms central to various physiological functions basically at three different levels: genome, proteome, and metabolome. Advances in genomic studies are paving the way to the development of scientific insights into nutritional sciences. Nutrigenetics and nutrigenomics are closely associated but two different areas of nutritional research. Both the fields involved the study of the implication between nutrition, metabolism, and genetic mechanism. The primary goal is to pinpoint nutrient-dependent health characteristics and nutrition dependent diseases. Another important area connected to these sciences concerns food composition and performance of quality assessment by studying proteomics and metabolic pathways. Nutrigenomics explains how the nutrients influences or effects the expression of the, while the response of different gene variants to nutrients or different dietary components is called Nutrigenetics. A personalized based diet can help us to know the right nutrient to take or avoid those who may potentially harm overall health. The goals are intended to alter or decrease the impact of hostile dietary changes that have occurred in since past in the developed world and more recently in the developing countries.
In-vitro antidiabetic activity of methanolic extract of leaves and fruits of Pouteria campechiana (Kunth) Baehni
Authors: Pai Akshata , Shenoy K. Chandrakala 
Published: January 2022

Introduction and Aim: Herbal medicine have been used to treat several ailments since decades. Pouteria campechiana (Kunth) Baehni belongs to the family Sapotaceae which is widely found around the world. In folk medicine, various parts of P. campechiana is used to treat various illness. Inhibition of alpha-amylase and alpha-glucosidase enzymes can be an important strategy in management of postprandial blood glucose level in non-insulin dependent diabetic patient. Hence, present study focused to evaluate the in vitro antidiabetic activity of leaf and fruit methanolic extract of Pouteria campechiana (Kunth) Baehni.

Materials and Methods: Methanolic extract of P. campechiana leaf (PCL) and fruit (PCF) was screened by biochemical assay such as ?-amylase inhibition activity by CNPG3 method (2-chloro-p-nitrophenyl-?-D-maltotrioside) and ?- glucosidase inhibition activity and in vitro cellular assay such as glucose uptake assay in 3T3-L1 cell line.

Results: Methanolic extract of P. campechiana leaf and fruit showed inhibition of ??Amylase and ??Glucosidase enzymes. The methanolic extract of P. campechiana leaf and fruit at varying concentrations (?g/ml), did not exhibit cytotoxicity against 3T3-L1 cell line after 24 hours of incubation. The test compounds PCL and PCF induced the uptake of 2?(N?(7?Nitrobenz?2?oxa?1,3?diazol?4?yl) Amino) ? 2?Deoxyglucose (2-NBDG) in 3T3L1 cells. PCF and PCL both showed almost similar activity of standard drug, Metformin at higher concentrations.

Conclusion: Based on the results, it can be concluded that methanolic leaf and fruit extract of P. campechiana possess antidiabetic activity.
Chest CT findings and experience in 100 COVID19 patients in Mosul city, Iraq
Authors: Wali Ahmed Abeer , Ahmed Rasha Nadeem , Muyaser Naif Mohamed , Tahseen Yahya Mohammed , Maulood Khalid Salih , Alchalabi Ghassan Basil , Mohammed Ahmed Ghiath 
Published: January 2022

Introduction: Due to lack of PCR kits in our area, as well as the extensive dissemination and peaking of COVID-19 since March 2020, our knowledge as radiologists has become increasingly relevant for recognizing CT patterns in order to diagnose and isolate COVID-19-infected patients. In 100 instances, the investigation began with the most prevalent CT chest abnormalities and the CT severity score index in relation to sex. The goal of this study is to better diagnose COVID-19-related lung injuries, enhance the diagnostic accuracy of chest CT scans, and track disease development in Mosul City.
Materials and Methods: From June 2020 to January 2021, one hundred patients were enrolled in this cross-sectional study in Mosul, with 71 males (71%) and 29 females (29%) ranging in age from 15 to 85 years, mean SD (53.2317.80). Non contrast chest CT were done as part of investigation tool on patients were suspected COVID-19 infection.
Results: A radiologist gathered data between 4 and 10 days after the onset of symptoms and evaluated it for lesion pattern, location, and severity. The commonest CT changes (ground glass opacity 55.23%, consolidation 17.44%, broncho vascular thickening 9.88%, crazy paving 5.81% and tree in bud 5.23%) were seen, along with less common pattern (bronchiectasis 1.74%, nodules 2.33%, reversed halo sign and pleural effusion 1.17%), and no lymphadenopathy were seen. Multilobe involvement was detected in 52/100 instances (68.92%), while peripheral affection was seen in 52/100 cases (65%). The higher CT severity score 4 and 5 with male gender were found to have a significant link (P value 0.002).
Conclusion: CT pulmonary are useful as a physician's helper for management and as an excellent predictor of disease severity and patient outcome. In patients with COVID-19 positive infection, the CT scan severity score is highly linked to laboratory findings, hospital stay, and oxygen demands.
Novel urinary markers: taurine, dopamine and L-fucose levels in predicting neonatal seizures
Authors: B. S. Varashree , Poduri Sravya , Lewis Leslie Edward , Shenoy Belle Vijetha 
Published: January 2022

Introduction and Aim: Neonatal seizure is an age specific neurological emergency. Their unique pathophysiological mechanism has become subject of interest for many research studies. The recurrence risk for seizures is high during neonatal period and currently used treatment strategies have limited efficacy in preventing it. From past decades although the treatment has not changed, there is a gradual progress in various mechanisms that are involved in generation of seizures and their response to anti-epileptics. With the emergence of new biochemical parameters for risk assessment in patients with seizures, there is a strong need for their comparative evaluation in order to evaluate their potential clinical application. So, this study was carried out to compare the urine levels of taurine, dopamine and fucose in assessing their role in mechanism of seizure.

Materials and Methods: After obtaining ethical approval and consent from parents total 43 neonates, urine taurine, dopamine and fucose were measured in 24 cases of seizures and 19 apparently healthy normal controls. Dopamine and Taurine were measured using ELISA and L-fucose by Dische and Shettles method.

Results: The median level of urine fucose was significantly higher in male neonates, taurine was significantly decreased in cases compared to that of controls. Males had higher preponderance to develop seizures. The median levels of urine dopamine were high in cases compared to controls but has not showed any significance.

Conclusion: Amino acid like taurine, carbohydrate moiety like fucose and a neuromodulator like dopamine may have a mechanistic role in development of seizures in neonatal period.