bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neoplastic Cellularity Assessment in Molecular Testing
Authors: Devereaux Kelly A. , Souers Rhona J. , Graham Rondell P. , Portier Bryce P , Surrey Lea F. , Yemelyanova Anna , Vasalos Patricia , Trembath Dimitri G. , Moncur Joel T. 
Published: January 2022

Context.—
Neoplastic cellularity assessment has become an essential component of molecular oncology testing; however, there are currently no best practice recommendations or guidelines for this potentially variable step in the testing process.

Objective.—
To describe the domestic and international practices of neoplastic cellularity assessment and to determine how variations in laboratory practices affect neoplastic cellularity assessment accuracy.

Design.—
Data were derived from 57 US and international laboratories that participated in the 2019 College of American Pathologists Neoplastic Cellularity Proficiency Testing Survey (NEO-B 2019). NEO-B 2019 included 29 laboratory practice questions and 5 images exhibiting challenging histologic features. Participants assessed the neoplastic cellularity of hematoxylin-eosin–stained digital images, and results were compared to a criterion standard derived from a manual cell count.

Results.—
The survey responses showed variations in the laboratory practices for the assessment of neoplastic cellularity, including the definition of neoplastic cellularity, assessment methodology, counting practices, and quality assurance practices. In some instances, variation in laboratory practice affected neoplastic cellularity assessment performance.

Conclusions.—
The results highlight the need for a consensus definition and improved standardization of the assessment of neoplastic cellularity. We put forth an initial set of best practice recommendations to begin the process of standardizing neoplastic cellularity assessment.
Closed fishing season law a positive instrument to minimize illegal fishing of the remaining stock of Arapaima sp. In the Brazilian Amazon
Authors: Freitas Helen Cristina Parazzi de , Sousa Raniere Garcez Costa 
Published: January 2022

The increasing demand for fish on a global level has caused an intensification of fishing and, as a consequence, overfishing of fish stock. The pirarucu (Arapaima sp.) is no exception since it is a highly appreciated fish species in the Amazon region, and the growth in fishing activities of this species was responsible for its inclusion in the International Union for Conservation of Nature's red list of Threatened species (IUNC). The current study assessed illegal fishing of pirarucu in the Brazilian Amazon, for the periods preceding and following the implementation of the Closed Fishing Season Law (CFSL), and was carried out using the analysis of data issued by the Brazilian Institute of the Environment and Renewable Natural Resources (IBAMA) Agency for the Brazilian Amazon, from January 1992 to December 2017. A total of 1,829 metric tons of pirarucu were confiscated, and of this amount, 78.13% corresponded to fiscalization which occurred in the basins of the Solimões and Negro rivers. The mean rates in the 26 years of confiscation of illegally fished pirarucu proved that before the implantation of the CFSL, the illegal fishing of this specie was intense, whereas after the implementation of this law, there was a significant reduction in the number of confiscations. The implementation of the CFSL combined with other restrictive procedures (fishing agreements and inspections) regarding pirarucu fishing has inhibited the illegal fishing of the species. However, in order to maintain this resource, government fishing management policies need to be aware of the need for the preservation of natural renewable resources (fish and their habitats) and the interaction between them, while also considering social and economic development in the region.
Noticias en Tierra de Nadie, de Concha Jerez y José Iges. La utopía fragmentaria, bromas aparte
Authors: Álvarez-Fernández Miguel 
Published: January 2022

Este análisis de la obra radiofónica Noticias en Tierra de Nadie, realizada conjuntamente por los artistas intermedia Concha Jerez y José Iges en 2003, permite cotejar la dimensión política de este proyecto con las aproximaciones al espacio público radiofónico propias de otras creaciones como La guerra de los mundos, de Orson Welles, o Clases de música en la granja, de Llorenç Balsach. Se perfila así el concepto de “interferencia” (asociado aquí al “principio de yuxtaposición”), que se propone dividir en tres tipologías: técnicas, programáticas y conceptuales. Esta última modalidad se pone en relación con la idea de “parodia”, si bien Noticias en Tierra de Nadie escapa de esa categoría (como también de otras estrategias relacionadas con el humorismo, cuya presencia en trabajos estéticamente cercanos al de Jerez/Iges es igualmente analizada) y propone, más bien, una particular aproximación a la noción de utopía, entendida de una manera característicamente fragmentaria.
Claves para la estética y la filosofía a partir de Theodor Wiesengrund Adorno
Authors: Notario Ruiz Antonio 
Published: January 2022

Reseña del libro: Vidal, Vanessa, Esto no tiene sentido: la interpretación materialista del arte. Valencia, Universitat de València, Servei de Publicacions, Estética & Crítica 45, 2021
The Immediate Effect of Steam Bath and Sauna Bath on Heart Rate Variability and Body Composition in Obese Individuals: A Comparative Study
Authors: Tripathi Mayank , Sujatha K. J. , Shetty Prashanth 
Published: January 2022

Aim: The present study was designed to evaluate and compare the immediate effects of steam bath and sauna bath on body composition and Heart Rate Variabilities in individuals with obesity.
Study Design: Prospective randomised comparative trial.
Materials and Methods: Participants visiting Shantivana Nature cure hospital with age ranging from 18 to 32, without any comorbidities and Body Mass Index (BMI) more than 31 kg/m2 were appraised about the study protocol and after getting informed consent were divided into Steam bath group (n = 50) and Sauna bath group (n = 50) and were administered one sitting of Steam bath and sauna bath for 15 minutes. The Heart Rate Variability (HRV) and Body Fat Analyser data was recorded before and after one sitting of treatment. The data was analysed using JASP (version 0.14.1.0) software and parametric and non-parametric tests were employed based on the normal distribution.
Results: Marked changes were observed in BMI (p= 0.022), Total Body Water (TBW; p<0.0001), Heart Rate (HR; p= 0.002), RR Interval (p< 0.001), NN50 (p=0.013), pNN50 (p=0.0001), variables in the Steam bath group after comparing with the baseline. In the Sauna bath group significant changes (in %) were seen in Body weight (BW; p<0.001), BMI (p<0.001), Free-Fat Mass (FFM; p= 0.004), Basal Metabolic Rate (BMR; p< 0.001), Systolic Blood Pressure SBP; p= 0.008), HR (p<0.001), Mean RR (p<0.0001), RMSSD (p=0.005), pNN50 (p<0.0001), Very low frequency (VLF; p<0.0001), Low Frequency (LF; p<0.001), High Frequency (HF; p<0.001), LF/HF (p<0.001). When comparing steam bath with sauna bath group, the variables Diastolic Blood Pressure (DBP; p=0.002), HR (p= 0.021), RMSSD (p<0.001), RMSSD (p<0.001), NN50 (p<0.001), pNN50 (p<0.001), VLF (p<0.001) showed significant changes.
Conclusion: The present study concludes that single dose of steam bath and sauna bath reduces the body weight by acting on the total body water percentage, reduces diastolic blood pressure, and causes vagal dominance. Sauna bath also increases basal metabolic rate which further helps in improving metabolism in the body and further helps in reducing body weight.
Evolutionarily relevant aggressive functions: Differentiating competitive, impression management, sadistic and reactive motives
Authors: Dane Andrew V. , Lapierre Kiana R. , Andrews Naomi C. Z. , Volk Anthony A. 
Published: January 2022

AbstractThis study investigated early adolescents' (ages 9–14; M = 11.91) self‐reported, evolutionarily relevant motives for using aggression, including competitive, impression management, sadistic, and reactive functions, and examined differential relations with a range of psychosocial characteristics. As expected, competitive functions were associated with aggression and victimization in which the perpetrator had equal or less power than the victim, in line with the view that these are aversive and appetitive motives related to competition with rivals. Impression management and sadistic functions were associated with bullying and coercive resource control strategies (the latter for boys only), consistent with expectations that these are appetitive motives, with the former being more goal‐directed and the latter somewhat more impulsive. Finally, as hypothesized, reactive functions were associated with emotional symptoms, hostility, victimization by bullying, and aggression by perpetrators with equal or less power than the victim, consistent with theory and research conceptualizing reactive aggression as an impulsive, emotion‐driven response to provocation. The benefits of studying a wide range of evolutionarily relevant aggressive functions are discussed.
The fading affect bias is disrupted by false memories in two diary studies of social media events
Authors: Gibbons Jeffrey A. , Dunlap Spencer , Friedmann Emma , Dayton Clare , Rocha Gabriela 
Published: January 2022

AbstractUnpleasant affect fades faster than pleasant affect, and this phenomenon is referred to as the fading affect bias (FAB). The FAB is moderated and mediated by many variables, including rehearsal and memory specificity, and researchers have emphasized the importance of memory for the FAB, but research has not evaluated the link of the FAB to objective memory measures. Using diary methodology across the span of 1 week, the current study examined the relation of event memory to the FAB for (1) social media events in Experiment 1 (n = 30) and (2) social media and non‐social media events with longer titles in Experiment 2 (n = 63) than in Experiment 1. The FAB was negatively predicted by false memories for (1) social media events in Experiment 1 and (2) both social media and non‐social media events in Experiment 2. These relations were mediated by rehearsals in both experiments. Implications are discussed.
Modulating the Ferroelectricity of Hafnium Zirconium Oxide Ultrathin Films via Interface Engineering to Control the Oxygen Vacancy Distribution
Authors: Lee Joonbong , Song Myeong Seop , Jang Woo‐Sung , Byun Jinho , Lee Hojin , Park Min Hyuk , Lee Jaekwang , Kim Young‐Min , Chae Seung Chul , Choi Taekjib 
Published: January 2022

AbstractHafnium oxides‐based ferroelectric materials are promising for applications in nonvolatile memory devices. To control the ferroelectricity of such materials, it is necessary to tune their polymorphism, interfacial features, and defect (oxygen vacancy) distribution. A strategy is described for enhancing the ferroelectric properties of polycrystalline hafnium zirconium oxide (HZO) ultrathin films by modifying the oxygen pressure during the device preparation stage, which involves thermal annealing of TiN electrodes that serve as oxygen reservoirs. Microstructural and chemical characterizations along with theoretical analysis reveal that interfacial layers of TiO2−x (or TiOxNy) can characteristically form between the TiN electrode and the HZO thin film, depending on the oxygen treatment conditions. These interfacial layers directly affect the polymorphic distribution of the as‐deposited HZO. In particular, the engineered interfacial TiO2−x layer facilitates the generation and stabilization of ferroelectric orthorhombic phase HZO by promoting the uniform distribution of oxygen vacancies. Electric field cycling tests further highlight the enhanced ferroelectric polarization and coercive voltage following interfacial engineering. The results presented herein demonstrate successful tuning of the structural and interfacial properties of polycrystalline HZO devices, thus enabling control over their ferroelectric characteristics, which is critical for the fabrication of devices with designed functionality.
Investigations of Intramolecular Hydrogen Bonding Effect of a Polymer Brush Modified Silicon in Lithium‐Ion Batteries
Authors: Hailu Alem Gebrelibanos , Ramar Alagar , Wang Fu‐Ming , Wu Nae‐Lih , Yeh Nan‐Hung , Hsu Chun‐Chuan , Chang Yung‐Jen , Tiong Pei‐Wan Lester , Yuwono Rio Akbar , Khotimah Chusnul , Wang Chun‐Chieh 
Published: January 2022

AbstractSilicon (Si) has the maximum capacity compared with the conventional graphite, which can dramatically increase the energy density of the battery. However, due to some tremendous drawbacks of Si material such as electrochemical irreversibility and volume expansion on alloy reaction, pure Si cannot be used in large quantities in the anode electrode. In this research, a polymer brush core‐shell structure (PBCS) on Si nanoparticle provides three significant functions because of the intramolecular effect of hydrogen bonding with PBCS and the binder delivers a good dispersion in the slurry, a mechanical protection during cycling, and excellent ionic conductivity for high‐rate tests. The carbonyl groups of polymer brush on Si surface are fabricated to enhance lithium‐ion diffusion and the adjustment of attraction and repulsion by intramolecular hydrogen bonding effect with binder in between each Si particles. The PBCS‐Si electrode shows the first coulombic efficiency is 87.1%; the retentions are 92.5% (0.1C/ 0.1C) for 200 cycles and 86.2% (0.5C/ 0.5C) for 400 cycles. Operando TXM displays that the PBCS structure significantly protects the nano Si from cracking owing to the high elastic function and intramolecular hydrogen bonding effect of the PBCS. With this novel PBCS‐Si material, a high energy density lithium‐ion battery can be expected.
Progress and Trends in Nonaqueous Rechargeable Aluminum Batteries
Authors: Shen Linghua , Du Xianfeng , Ma Mingbo , Wang Shixin , Huang Shan , Xiong Lilong 
Published: January 2022

AbstractIt is important to research new energy storage technology for substituting the deficiencies of current energy storage devices, i.e., the poor energy density of lead‐acid batteries, the high cost of lithium‐ion batteries, etc. Rechargeable aluminum batteries (RABs) are regarded as one of the most promising storage devices due to the abundance of the materials required, superior security, and decent energy density of aluminum anodes. Nevertheless, there are some significant challenges, such as the developing energy density of cathodes, corrosion, and the high cost of electrolytes, which set obstacles to the industrialization of RABs. For avoiding the pitfalls of RABs research and boosting the development of RABs, the recent progress and trends in RABs covering mechanisms, components of RABs (electrodes, electrolytes, separators, and current collectors) and technology of assembly and packaging of devices are summarized and proposed.
2D Polymer Nanosheets for Membrane Separation
Authors: Wang Fei , Zhang Zhao , Shakir Imran , Yu Chengbing , Xu Yuxi 
Published: January 2022

AbstractSince the discovery of single‐layer graphene in 2004, the family of 2D inorganic nanosheets is considered as ideal membrane materials due to their ultrathin atomic thickness and fascinating physicochemical properties. However, the intrinsically nonporous feature of 2D inorganic nanosheets hinders their potential to achieve a higher flux to some extent. Recently, 2D polymer nanosheets, originated from the regular and periodic covalent connection of the building units in 2D plane, have emerged as promising candidates for preparing ultrafast and highly selective membranes owing to their inherently tunable and ordered pore structure, light weight, and high specific surface. In this review, the synthetic methodologies (including top–down and bottom–up methods) of 2D polymer nanosheets are first introduced, followed by the summary of 2D polymer nanosheets‐based membrane fabrication as well as membrane applications in the fields of gas separation, water purification, organic solvent separation, and ion exchange/transport in fuel cells and lithium‐sulfur batteries. Finally, based on their current achievements, the authors’ personal insights are put forward into the existing challenges and future research directions of 2D polymer nanosheets for membrane separation. The authors believe this comprehensive review on 2D polymer nanosheets‐based membrane separation will definitely inspire more studies in this field.
Genetic Aberrations and Interaction of NEK2 and TP53 Accelerate Aggressiveness of Multiple Myeloma
Authors: Feng Xiangling , Guo Jiaojiao , An Gang , Wu Yangbowen , Liu Zhenhao , Meng Bin , He Nihan , Zhao Xinying , Chen Shilian , Zhu Yinghong , Xia Jiliang , Li Xin , Yu Zhiyong , Li Ruixuan , Ren Guofeng , Chen Jihua , Wu Minghua , He Yanjuan , Qiu Lugui , Zhou Jiaxi , Zhou Wen 
Published: January 2022

AbstractIt has been previously shown that (never in mitosis gene A)‐related kinase 2 (NEK2) is upregulated in multiple myeloma (MM) and contributes to drug resistance. However, the mechanisms behind this upregulation remain poorly understood. In this study, it is found that amplification of NEK2 and hypermethylation of distal CpG islands in its promoter correlate strongly with increased NEK2 expression. Patients with NEK2 amplification have a poor rate of survival and often exhibit TP53 deletion, which is an independent prognostic factor in MM. This combination of TP53 knockout and NEK2 overexpression induces asymmetric mitosis, proliferation, drug resistance, and tumorigenic behaviors in MM in vitro and in vivo. In contrast, delivery of wild type p53 and suppression of NEK2 in TP53−/− MM cell lines inhibit tumor formation and enhance the effect of Bortezomib against MM. It is also discovered that inactivating p53 elevates NEK2 expression genetically by inducing NEK2 amplification, transcriptionally by increased activity of cell cycle‐related genes like E2F8 and epigenetically by upregulating DNA methyltransferases. Dual defects of TP53 and NEK2 may define patients with the poorest outcomes in MM with p53 inactivation, and NEK2 may serve as a novel therapeutic target in aggressive MM with p53 abnormalities.
Transcriptome‐wide identification and analysis of the KT/HAK/KUP family in black goji under NaCl stress
Authors: Wei Jia , Tiika Richard John , Ma YanJun , Yang HongShan , Cui GuangXin , Tian FuPing , Zhang YongTao , Duan HuiRong , Ma Rui 
Published: January 2022

AbstractBlack goji (Lycium ruthenicum Murr.) is a typical salt‐tolerant plant that can maintain normal growth under high NaCl treatment and is distributed in saline areas in northwestern China. The KT/HAK/KUP (KUP) gene family plays an essential role in K absorption and transport process. However, the role of the KUP gene family in the salt tolerance of black goji has not yet been investigated. Therefore, the objective was to identify the members of LrKUPs in black goji by bioinformatics based on Illumina sequencing transcriptome data. Moreover, the expression profiles of LrKUPs under different NaCl treatments were analyzed based on fragments per kilobase of exons per million mapped reads (FPKM) values above 5, using real‐time quantitative polymerase chain reaction (RT‐qPCR). A total of 31 LrKUPs were identified, and 19 LrKUPs containing the same K+ transporter domain were used to construct a phylogenetic tree and classified into four clusters. Six LrKUPs with full‐length sequences were discovered by open reading frame (ORF). They were localized to the plasma membrane and the predicted transmembrane regions were 12–14. The selected LrKUPs exhibited different expression patterns under NaCl stresses. It is noteworthy that LrKUPs (‐4, ‐9, ‐11, ‐31) from leaves and stems could withstand higher concentration and longer duration of salt stress compared with roots. In the present study, the KUP gene family was discovered as a potential stress resistance regulator for black goji growth and development, this provides candidate genes for future functional research of LrKUPs.
Synthesis and properties of a novel autocatalytic phthalonitrile monomer and its copolymerization with multi‐functional fluorene‐based benzoxazine monomers
Authors: Wang Ting , Wang Zi‐long , Dayo Abdul Qadeer , Shi Cheng‐yu , Liu Hui‐bo , Pan Zhong‐cheng , Gorar Athar Ali Khan , Wang Jun , Zhou Heng , Liu Wen‐bin 
Published: January 2022

AbstractA novel autocatalytic phthalonitrile monomer [4,4′‐(((((oxy‐bis [4,1‐phenylene]) bis (azanediyl)) bis (methylene)) bis (2‐methoxy‐4,1‐phenylene)) bis (oxy)) diphthalonitrile, OPD] is obtained by nucleophilic substitution of 4‐nitro‐phthalonitrile and bisphenol compound [4,4′‐(((oxy bis [4,1‐phenylene]) bis (azanylylidene)) bis (methanylylidene)) bis (2‐methoxyphenol)]. Bisphenol compound is a reductant with secondary amine groups of Schiff base derived from the reaction of vanillin and 4,4′‐diaminodiphenylether. The OPD monomer has a self‐catalytic polymerizing reaction. OPD monomer has good processability, and the processing window was 130°C. Moreover, OPD polymer [poly(OPD)] shows higher glass‐transition temperature (345°C). The 5% and 10% thermal decomposition temperatures of poly(OPD) and char yield at 800°C are 407, 451°C, and 69%, respectively. To further improve the properties of poly(OPD), the OPD monomer was modified by multi‐functional fluorene‐based benzoxazine monomers (MFFB) due to their excellent reaction activities. The results showed that OPD/MFFB systems had high reaction activities. The similar thermal stabilities between OPD and MFFB can give stable and excellent thermal stability to the poly(OPD/MFFB). Compared with poly(OPD), the Tg values of poly(OPD/MFFB) were significantly increased, and their stiffness values were reduced. The tensile, flexural, and impact properties for poly(OPD/MFFB) were improved significantly.
The mitochondrial genome of Chelonus formosanus (Hymenoptera: Braconidae) with novel gene orders and phylogenetic implications
Authors: Yuan Rui‐Zhong , Zhou Jin‐Jin , Shu Xiao‐Han , Ye Xi‐Qian , Tang Pu , Chen Xue‐Xin 
Published: January 2022

AbstractChelonus formosanus Sonan is an important egg‐larval parasitoid of noctuid moths and a potential candidate for understanding interactions between host and parasitoid mediated by polydnavirues (PDVs). We sequenced and annotated the mitochondrial genome of C. formosanus, which is 15,466 bp in length and possesses 38 mitochondrial genes. However, unlike most animal mitochondrial genomes, it contains one extra trnF gene. There are five transfer RNA (tRNA) rearrangement events compared with the ancestral gene order, which is a novel rearrangement type in Hymenoptera for all published mitogenomes so far. Phylogenetic trees supported C. formosanus from the subfamily Cheloninae was closely related to the subfamily Cardiochilinae and Microgastrinae.