bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUASI PROGRAM PEMBERDAYAAN MASYARAKAT DALAM PENGEMBANGAN KOLAM IKAN NILA DIDESA PERHENTIAN LUAS KABUPATEN KUANTAN SINGINGI
Authors: Sutrianika Sutrianika , Febrina Rury 
Published: September 2022

Penelitian ini bertujuan untuk menilai atau mengevaluasi hasil program pemberdayaan masyarakat dalam pengembangan kolam ikan nila.metode penelitian menggunakan kualitatif deskriptif.hasil penelitian evaluasi program menunjukkan dengan adanya evaluasi hasil,evaluasi proses dan evaluasi dampak pada evaluasi pengembangan kolam ikan nila sebagian besar sudah sesuai dengan tujuan program dengan apa yang diharapkan.di evaluasi proses adanya pembinaan dan pelatihan dalam pengembangan kolam ikan,penyedian sarana dan prasarana sertapengembangan usaha kolam ikan yang merupakan strategi yang cukup baik terhadap pelaksanaan program pengembangan kolam ikan nila dan terdapat beberapa kendala pada evaluasi proses yaitu dari segi pemasaran hasil pembudidaya seperti pembeli yang tidak pasti, modal yang tidak jalan dan anggapan masyarakat terhadap pembudidayaan kolam ikan masih kurang.pada evaluasi dampak dalam pengembangan budidaya kolam ikan nila ini sudah membawakan dampak yang positif kepada masyarakat dalam pengembangan kolam ikan nila yang bertujuan untuk meningkatkan ekonomi masyarakat,membuka peluang usaha bagi masyarakat serta untuk mengatasi masalah pengangguran ekonomi.
ANALISIS KINERJA BADAN PUSAT STATISTIK DALAM PENETAPAN STANDAR MASYARAKAT MISKIN DI KOTA BATAM (Studi Kasus di Kecamatan Galang)
Authors: Hasanudin Hasanudin , Lestari Linayati , Sutarto Dendi 
Published: September 2022

Tujuan yang ingin dicapai dalam penelitian ini adalah untuk mengetahui mengetahui analisis kinerja Badan Pusat Statistik (BPS) Kota Batam dalam menetapkan standar masyarakat miskin dengan studi kasus di Kecamatan Galang. Penelitian ini diharapkan dapat menambah wawasan dalam kajian ilmu Pemerintahan yang berkaitan dengan kinerja Badan Pusat Statistik (BPS) Kota Batam dalam menetapkan standar masyarakat msikin dengan studi kasus di Kecamatan Galang tahun 2018. Adapun secara akademis diharapkan skripsi ini dapat dijadikan sebagai referensi bagi peneliti yang akan datang yang akan melakukan penelitian yang lebih luas tentang analisis kinerja Badan Pusat Statistik (BPS) Kota Batam dalam menetapkan standar masyarakat msikin dengan studi kasus di Kecamatan Galang tahun 2018. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif dengan menggunakan studi kasus. Penelitian yang berusaha menggambarkan kenyataan serta keadaan objek yang diteliti secara sistematis, faktual dan akurat untuk dianalisis secara mendalam. Berdasarkan pembahasan pada bab 3 dapat disimpulkan bahwa secara umum penetapan masyarakat miskin berdasarkan kriteria masyarakat misikin yang telah ditetapkan oleh BPS di Kecamatan Galang belum akurat. Hal tersebut dapat dilihat dari hasil pendataan, perilaku petugas dan masyarakat, komparatif atau membandingkan hasil sebelum dan setelah dilaksanakan pendataan terhadap rumah tangga sasaran maupun dari penetapan kriteria masyarakat miskin itu sendiri.
Evaluation of the influence of actual nutrition on sports performance and the quality of performance at competitions
Authors: Badtieva V. A. , Balandin M. Yu. , Vybornov V. D. , Rybakova P. D. , Meshtel A. V. 
Published: September 2022

Objective: To determine the effect of personal diet on sports performance and competition results female handball players of the Major League and Super League.Methods: The study involved athletes of the women’s handball team «LUCH» (Moscow), the major league (16–17 years old) – n=10 and the super league (17–36 years old)-n =16. Athletes are at the competitive stage of sports training. Qualification: Candidate Master of Sports, Master of Sports and Master of Sports of international class. Research methods: diet composition assessment, body composition assessment, assessment of physical performance, the quality of gaming assessment and athlete’s calorie consumption based on heart rate monitoring. The analysis of the relationship between the parameters of diet composition, of the quality of game actions and estimate VO2 capacity was carried out.Results: Handball players have significant deviations in the diet composition from the established norms and identified calorie consumption. The key deviations are: lack of calories of the diet (14 %), lack of carbohydrates (24 %), lack of vitamins (30 %), lack of minerals (31 %), lack of fiber (46 %). A number of significant relationships were revealed between deviations in the quality of nutrition and assessments of the quality of game actions, and the results of a sports performance test.Conclusions: The inclusion of a nutrition specialist in the work of a team is required for individual and group consultations, training events.
Implementasi Kebijakan Sistem Informasi Manajemen (SIM-Siluhtan) dalam Pelaksanaan Program Dekonsentrasi Penyuluhan Pertanian di Provinsi Kalimantan Utara
Authors: Sallolo Yohanis , Aripin Sofjan , Raharjo Djoko 
Published: September 2022

Abstract
SIM-Siluhtan is website-based information system used as a media for reporting the implementing of the deconcentration program of agriculture extention (PDPP) in North Kalimantan Province since 2017. The research wasconducted in three districts, Bulungan, Nunukan, Malinau using data from 2018-2019 to decribe and analyze SIM-Siluhtan implementation policies in the implementing at the deconcentration program activities, as well as the factors that support and hinder the implementation and also the effort made in implementing. This study uses a descriptive qualitative method based on Edward III’s theory to describe and explore the fact that the implementation of public policy can be effective, depending on the four factors thae influence its success, namely communication, resources, disposition, and bureaucratic structure.
The results showed that overall the stage of the SIM-Siluhtan implementation process with a span of control involving the provincial, distric and subdistrict /BPP levels were successful in achieving the performance target and by prioritizing the principles of transparency and publication in the policy implementation which is intensive with support of human resource capabilities of the implementer in carrying out their duties and aothorities so that collaboration and communication are build out which supported by publication of media communication, namely Facebook, WhatsApp, as well as adequate budged support and infrastructure, althouh not maximized due to technical contraints in the field.
Keywords : SIM-Siluhtan Implementation, Communication, Resource, Disposition, Bureaucratic Structure.
Alterations of gut microbiota in cirrhotic patients with spontaneous bacterial peritonitis: A distinctive diagnostic feature
Authors: Zhou Zumo , Lv Hui , Lv Jiawen , Shi Yongming , Huang Heqing , Chen Lin , Shi Ding 
Published: September 2022

BackgroundSpontaneous bacterial peritonitis (SBP) is a severe infection in cirrhotic patients that requires early diagnosis to improve the long-term outcome. Alterations in the gut microbiota have been shown to correlate with the development and progression of liver cirrhosis. However, the relationship between SBP and gut microbiota remains unknown.MethodsIn this study, we applied 16S rRNA pyrosequencing of feces to ascertain possible links between the gut microbiota and SBP. We recruited 30 SBP patients, 30 decompensated cirrhotic patients without SBP (NSBP) and 30 healthy controls. Metagenomic functional prediction of bacterial taxa was achieved using PICRUSt. ResultsThe composition of the gut microbiota in the SBP patients differed remarkably from that in the NSBP patients and healthy individuals. The microbial richness was significantly decreased, while the diversity was increased in the SBP patients. Thirty-four bacterial taxa containing 15 species, mainly pathogens such as Klebsiella pneumoniae, Serratia marcescens and Prevotella oris, were dominant in the SBP group, while 42 bacterial taxa containing 16 species, especially beneficial species such as Faecalibacterium prausnitzii, Methanobrevibacter smithii and Lactobacillus reuteri, were enriched in the NSBP group. Notably, we found that 18 gene functions of gut microbiota were different between SBP patients and NSBP patients, which were associated with energy metabolism and functional substance metabolism. Five optimal microbial markers were determined using a random forest model, and the combination of Lactobacillus reuteri, Rothia mucilaginosa, Serratia marcescens, Ruminococcus callidus and Neisseria mucosa achieved an area under the curve (AUC) value of 0.8383 to distinguish SBP from decompensated cirrhosis.ConclusionsWe described the obvious dysbiosis of gut microbiota in SBP patients and demonstrated the potential of microbial markers as noninvasive diagnostic tools for SBP at an early stage.
Causal associations between thyroid dysfunction and COVID-19 susceptibility and severity: A bidirectional Mendelian randomization study
Authors: Zhang Zhihao , Fang Tian , Lv Yonggang 
Published: September 2022

BackgroundObservational studies have reported an association between coronavirus disease 2019 (COVID-19) risk and thyroid dysfunction, but without a clear causal relationship. We attempted to evaluate the association between thyroid function and COVID-19 risk using a bidirectional two-sample Mendelian randomization (MR) analysis.MethodsSummary statistics on the characteristics of thyroid dysfunction (hypothyroidism and hyperthyroidism) were obtained from the ThyroidOmics Consortium. Genome-wide association study statistics for COVID-19 susceptibility and its severity were obtained from the COVID-19 Host Genetics Initiative, and severity phenotypes included hospitalization and very severe disease in COVID-19 participants. The inverse variance-weighted (IVW) method was used as the primary analysis method, supplemented by the weighted-median (WM), MR-Egger, and MR-PRESSO methods. Results were adjusted for Bonferroni correction thresholds.ResultsThe forward MR estimates show no effect of thyroid dysfunction on COVID-19 susceptibility and severity. The reverse MR found that COVID-19 susceptibility was the suggestive risk factor for hypothyroidism (IVW: OR = 1.577, 95% CI = 1.065–2.333, P = 0.022; WM: OR = 1.527, 95% CI = 1.042–2.240, P = 0.029), and there was lightly association between COVID-19 hospitalized and hypothyroidism (IVW: OR = 1.151, 95% CI = 1.004–1.319, P = 0.042; WM: OR = 1.197, 95% CI = 1.023-1.401, P = 0.023). There was no evidence supporting the association between any phenotype of COVID-19 and hyperthyroidism.ConclusionOur results identified that COVID-19 might be the potential risk factor for hypothyroidism. Therefore, patients infected with SARS-CoV-2 should strengthen the monitoring of thyroid function.
Chemical characteristics of three-stage fog water in an agricultural city in China
Authors: Ge Panyan , Fan Shuxian , Wang Yuan , Zhang Sirui , Wu Haopeng , Shao Naifu , Zu Fan 
Published: September 2022

To investigate the relationships among the chemical compositions of fog droplets, atmospheric pollutants, and the fog microphysical characteristics, four fog cases were sampled in a comprehensive field experiment conducted at the Donghai site in an agricultural city, China, in the winter of 2020. The pH, electrical conductivity (EC), total ion concentration (TIC), and chemical compositions of the fog water were all size-dependent. High concentrations of non-sea-salt calcium (nssCa2+) and NH4+ led to the alkaline pH of 6.13–7.32. The TIC of fog water was relatively high, especially in small droplets of diameter within 4–16 μm (463527.9 μeq/L). The relatively high NO2− concentration was also found in the fog water, dominated by the non-homogeneous chemical reaction between NO2 and fog droplets. An interesting finding is that the TIC of fog water measured on December 12 was much higher than that measured on December 11. Compared to the first fog, the stronger thermal inversion and local emissions led to the higher concentration of atmospheric particles in the second fog. Generally, the relatively high concentration of atmospheric particles resulted in a large number of small-sized droplets, which had fast liquid-phase oxidation reaction rates and high gas-liquid conversion efficiencies, leading to a higher TIC in the fog water during the second fog.
Differential characteristics and driving forces of the spatial distribution of heritage trees in Luoyang, an ancient capital of China
Authors: Hou Heping , Zhang Longchong , Bi Huitao , He Jing , Cai Enxiang , Ren Wanqian 
Published: September 2022

Heritage trees have important historical, landscape, and ecological value. Exploring the spatial distribution pattern of heritage trees is of great importance to the construction of ecological civilization and the connotation of regional history and culture. This paper took 5,216 heritage trees in Luoyang, an ancient capital of China, as the research object and used geospatial analysis methods and a geographically weighted regression model to analyze the differences and driving forces of the spatial distribution of heritage trees. Results show that 1) the heritage trees in Luoyang were primarily Gleditsia sinensis, Sophora japonica, and Platycladus orientalis, and more than half of these trees were under 300 years old; 2) the high-density area formed a distribution pattern of “three cores, one ring, and two belts,” and the distribution of heritage trees had a positive spatial autocorrelation; 3) different driving factors in different regions had complex influences on the spatial distribution of heritage trees, and the order of influence was as follows: area of forest and orchard land &gt; elevation &gt; number of POIs (points of interest) &gt; distance to the nearest river &gt; slope &gt; number of immovable relics. The results could provide a comprehensive understanding of the spatial distribution of heritage trees to protect the ecological function of heritage trees and mine the cultural value of heritage trees.
Emerging trends and research foci of oncolytic virotherapy for central nervous system tumors: A bibliometric study
Authors: Cheng Kunming , Zhang Huan , Guo Qiang , Zhai Pengfei , Zhou Yan , Yang Weiguang , Wang Yulin , Lu Yanqiu , Shen Zefeng , Wu Haiyang 
Published: September 2022

BackgroundCentral nervous system tumor (CNST) is one of the most complicated and lethal forms of human tumors with very limited treatment options. In recent years, growing evidence indicates that oncolytic virotherapy (OVT) has emerged as a promising therapeutic strategy for CNSTs. And a considerable amount of literature on OVT-CNSTs has been published. However, there are still no studies summarizing the global research trends and hotspots of this field through a bibliometric approach. To fulfill this knowledge gap, bibliometric analysis was conducted based on all publications relating to OVT-CNSTs since 2000s.MethodsWe searched the Web of Science Core Collection for all relevant studies published between 2000 and 2022. Four different tools (online analysis platform, R-bibliometrix, CiteSpace and VOSviewer) were used to perform bibliometric analysis and network visualization, including annual publication output, active journals, contribution of countries, institutions, and authors, references, as well as keywords.ResultsA total of 473 articles and reviews were included. The annual number of publications on OVT-CNSTs showed a significant increasing trend. Molecular Therapy and Cancer Research were the most active and co-cited journals, respectively. In terms of contributions, there is no doubt that the United States occupied a leading position with the most publications (n=307, 64.9%) and the highest H-index (57). The institution and author that contributed the largest number of publications were Ohio State University and Chiocca EA, respectively. As can be seen from citation analysis, the current studies mainly focused on preclinical and phase I/II clinical results of various oncolytic virus for CNSTs treatment. Keywords co-occurrence and burst analysis revealed that the following research topics including immunotherapy, T-cells, tumor microenvironment, vaccine, blood-brain-barrier, checkpoint inhibitors, macrophage, stem cell, and recurrent glioblastoma have been research frontiers of this field and also have great potential to continue to be research hotspots in the future.ConclusionThere has been increasing attention on oncolytic viruses for use as CNSTs therapeutics. Oncolytic immunotherapy is a topic of great concern in this field. This bibliometric study provides a comprehensive analysis of the knowledge base, research hotspots, development perspective in the field of OVT-CNSTs, which could become an essential reference for scholars in this area.
The efficacy of paxlovid in elderly patients infected with SARS-CoV-2 omicron variants: Results of a non-randomized clinical trial
Authors: Zhong Weijie , Jiang Xiufeng , Yang Xiaosheng , Feng Tiantong , Duan Zhixin , Wang Wei , Sun Zhaoliang , Chen Lingyan , Nie Xin , Zhu Chuanlong , Zhang Wenchuan , Li Yi 
Published: September 2022

ObjectiveTo evaluate the efficacy of Paxlovid in treating Chinese elder patients infected with SARS-CoV-2 omicron variants.Materials and methodsWe performed a non-randomized, controlled trial in Shanghai, China. Participants infected with SARS-CoV-2 omicron variants were enrolled. All patients were divided into the Paxlovid group or the control group according to the Chinese guideline (version 9). The nucleic acid shedding time was the primary endpoint.ResultsAccording to the inclusion criteria, 142 patients infected with omicron variants were enrolled, 36 patients who did not receive paxlovid were assigned to the control group, and 106 were in the Paxlovid group. The baseline characteristics were similar in either group. No significant difference in BMI, age, time from onset to patient enrollment, the severity on first admission, vaccination status, comorbidity, first symptoms, and laboratory results were recorded. Compared to the control group, participants in the Paxlovid group had a shorter viral shedding time [11.11 (2.67) vs. 9.32 (2.78), P = 0.001].ConclusionIn Chinese elder patients infected with the variant of SARS-CoV-2 omicron, our data suggest that Paxlovid can significantly reduce the nucleic acid shedding time.
Effect of traditional Chinese exercise combined with massage on pain and disability in patients with lumbar disc herniation: A multi-center, randomized, controlled, assessor-blinded clinical trial
Authors: Zhou Xin , Kong Lingjun , Ren Jun , Song Pengfei , Wu Zhiwei , He Tianxiang , Lv Zhizhen , Zhang Shuaipan , Sun Wuquan , Zhang Jiafu , Cai Junhao , Zhu Qingguang , Fang Min 
Published: September 2022

BackgroundHerniation of the nucleus pulposus caused by disc degeneration and other reasons can cause low back pain and disability. In China, traditional Chinese exercises (TCEs) and traditional Chinese massage (TCM) are widely used to improve symptoms of pain and disability in patients with lumbar disc herniation (LDH). The safety and efficacy of combination therapy have not been studied.ObjectivesTo assess the effect of traditional Chinese exercise combined with massage vs. traditional Chinese massage alone on pain, disability, lumbar mobility and gait performance in patients with LDH.MethodsMulti-center, randomized clinical trial conducted at 4 hospitals in China and enrolling 272 patients with LDH. Participants were randomly assigned to TCEs plus TCM group or TCM alone group. The combined therapy group received 18 Tai Chi training sessions (30-min sessions 3 times a week) and regular TCM treatments over 6 weeks. The control group received TCM therapy alone and was instructed to maintain their usual daily physical activity. Outcome variables measured included Visual Analog Scale (VAS), Short Form of McGill Pain Questionnaire (SF-MPQ), Oswestry Disability Index (ODI), lumbar spine range of motion (ROM) and gait performance.ResultsAmong the 272 randomized participants, 259 completed the study. The mean VAS score was 51.77 mm at baseline in the TCEs plus TCM group, and 50.93 mm for the TCM alone group. The reduction in the VAS score at week 6 was greater in the TC group than in the TCM group with a mean difference of 4.05 (95% CI, 2.15–5.95; P &lt; 0.001), and the ODI score with between-group differences of 3.57 points (95% CI, 2.84–4.30 points; P &lt; 0.001). Similar significantly different results were observed in SF-MPQ, walking speed, cadence, and lumbar ROM. No serious adverse events were reported throughout the study period.ConclusionCompared with TCM alone, TCEs combined with TCM treatment performed better in reducing pain and improving disability. The combination therapy could be considered a valuable treatment option for LDH patients, with potential therapeutic utility for middle-aged and elderly patients with LDH.
The patient journey with NMOSD: From initial diagnosis to chronic condition
Authors: Delgado-Garcia Guillermo , Lapidus Sheryl , Talero Rosa , Levy Michael 
Published: September 2022

ObjectiveTo better understand the patient experience with neuromyelitis optica spectrum disorder (NMOSD) through the course of the illness.BackgroundNMOSD is a rare autoimmune disorder that causes recurrent inflammatory attacks of the optic nerve, spinal cord, and brain. Knowledge and awareness of NMOSD in the general medical community are often limited, resulting in potential delays in diagnosis and treatment.Design/methodsWe developed a comprehensive 101-question survey to understand the patient's perspective on their journey from initial presentation to present condition. The survey covered basic demographics, symptoms, medical tests used to reach a diagnosis, and the patient's psychosocial responses to their diagnosis. The survey included questions to determine internal consistency in responses. We shared the survey with members of the Neuromyelitis Optica (NMO) Clinic Facebook group and received responses from 151 patients. All data collected were self-reported and presented as summary statistics.ResultsThe majority of survey responses were from patients who were female (83%) and White (76%), Asian (7%), or African American (7%). Initial symptoms of disease included fatigue, pain, stiffness/spasticity, bladder and bowel dysfunction, cognitive/emotional symptoms, and visual disturbances. Initial reactions to NMOSD diagnosis were frequently fear, anxiety, and/or depression. Mean (SD) time to diagnosis was 2.2 (3.2) years. First contact with a medical professional was felt to be not helpful or somewhat helpful for many patients (71%), in part due to uncertain diagnosis and/or treatment. However, once referred to specialists (primarily neurologists), the majority of patients (87%) reported finding a professional who could help. Tests leading to diagnosis included magnetic resonance imaging, lumbar puncture, and blood tests for autoantibodies including aquaporin-4 (AQP4) and myelin oligodendrocyte glycoprotein (MOG). While approximately 30% of patients still felt challenged for a variety of reasons, most patients reported that having a diagnosis and being under the care of a specialist contributed to a comprehensive plan with hope for their future.ConclusionsThe NMOSD patient journey frequently begins with anxiety, fear, and frustration. Finding the right specialist and identifying appropriate screening tests can lead to earlier diagnosis and progression toward better patient outcomes.