bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Selenium Supplementation in Acute Ischemic Stroke Outcome
Authors: Sharifi-Razavi Athena , Karimi Narges , Jafarpour Hamed 
Published: January 2022

Background:
Selenium is a trace element that protects against cellular damage by oxygen radicals through selenoproteins. Ischemic stroke is associated with the generation of oxygen free radicals resulting in a condition of oxidative stress.

Objectives:
The present study aimed to evaluate the effect of selenium supplementation on short-term and long-term acute ischemic stroke outcomes.

Methods:
This was a randomized, parallel, outcome assessor blind, placebo-controlled feasibility study on ischemic stroke patients admitted in Bou-Ali Sina Hospital, Sari, Iran (2015–2017). Inclusion criteria were adults with accepted ischemic stroke by neuroimaging during the last 72h with a volume of at least one-third of MCA territory. The primary outcome was the short-term outcome measuring with the National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS) on day 7. The participants (44 patients) were randomized into two groups (22 in each group), one receiving intravenous selenium selenite for 5 days, and the other 40 cc normal saline as a placebo.

Results:
A total of 40 ischemic stroke patients (18 females, 22 males) with mean age of 68.2 ± 10 years were investigated. Selenium supplementation improved short-term outcome, 15.7% by using NIHSS (66% vs 42%, RR = 0.85 with CI = 0.54-1.35; NNT = 10; 95% CI = 5.15- 2.53, P = 0.51) and 46.3% by using mRS (57% vs 12%, RR = 0.52 with CI = 0.31-0.88; NNT = 3; 95% CI = 1.49 -7.59, P = 0.01). The long-term outcome did not change significantly by considering Barthel index >75 after 3 months in comparison to comparator group (33.3% vs 29.4%, RR = 1.13 with CI = 0.40-3.16; NNT = 26; 95% CI = 2.77 -3.54, P = 0.81].

Conclusions:
Selenium selenite supplementation in acute ischemic stroke can improve short-term outcome but cannot influence the long-term outcome.
Is Video-Oculography a Predictive Test for Myasthenia Gravis with Ocular Symptoms?
Authors: Sirin Tuba Cerrahoglu , Karaaslan Zerrin , Arkali Burcu N , Bekdik Pınar , Akinci Tuba , Candan Fatma , Akarsu Emel Oguz , Baslo M Baris , Orhan Elif Kocasoy , Oge A Emre 
Published: January 2022

Background and Objective:
The aim of this study was to evaluate the contribution of extraocular muscle function testing with video-oculography (VOG), which is a noninvasive and easily applicable method of recording eye movement with digital cameras, to the diagnosis of myasthenia gravis (MG) in patients without any clinical eye movement abnormalities.

Methods and Materials:
The study included 18 patients prediagnosed with ocular MG: MG Group (N = 7) with abnormal, and non-MG Group (N = 11) with normal single-fiber electromyography. Control group included 50 healthy volunteers. Ocular movements were recorded with the EyeSeeCam VOG device.

Results:
The inward latency of the 10° horizontal saccade and the downward latency of the 10° vertical saccade were significantly delayed; and the downward amplitude of the 10° vertical saccade was significantly lower in the MG group. Receiver operating characteristic curve analyses showed high specificity values for the discrimination of MG patients.

Conclusions:
This study supports the usefulness of the VOG device in revealing subclinical extraocular muscle involvement in MG.
Predictors of Outcome in Spontaneous Intracerebral Hemorrhage with Special Reference to Hyponatremia
Authors: Porwal Tulika , Mohanty Smita 
Published: January 2022

Objective:
The study was done to find the various clinical, biochemical and radiological predictors of outcome in spontaneous intracerebral hemorrhage (SICH) patients and to assess the role of hyponatremia as a predictor of in-hospital mortality.

Materials and Methods:
This was a hospital based prospective observational study conducted in the department of Medicine, VMMC and Safdarjang Hospital, New Delhi, India on 75 adults (>18 years of age, both male and female) presenting with SICH. Various parameters comprising demographic, clinical, laboratory, and radiological variables along with stroke severity were assessed and studied as predictors of in-hospital outcome, i.e., mortality and disability at the time of discharge as assessed by modified Rankin's Scale (mRS) in 75 SICH patients presenting to the emergency department. Furthermore, the role of hyponatremia as a predictor of in-hospital mortality was studied.

Results:
Out of 75 patients enrolled in the study, 40% (n = 30) of the patients died in the hospital and 60% (n = 45) were discharged. Out of the discharged category, 80% (n = 36) had mild disability with mRS 1–3 and 20% (n = 9) had moderate-to-severe disability with mRS 4-5. National Institute of Health Stroke Scale (NIHSS) at the time of hospitalization was found to be the significant independent predictor of in-hospital mortality and higher mRS score at discharge. Furthermore, Glasgow Coma Scale (GCS) ≤4 and NIHSS >12 were significantly associated with in-hospital mortality. Hyponatremia was found in 44% (n = 33) of the patients at the time of hospitalization and out of them sodium level got corrected in 15.15% (n = 5). Out of the 42 normonatremic patients 31% (n = 13) developed hyponatremia in subsequent days during hospitalization. No association was found between hyponatremia and in-hospital mortality.

Conclusion:
Our study highlights the fact that SICH is associated with high in-hospital mortality. NIHSS score at the time of hospitalization is an independent predictor of in-hospital mortality and disability at discharge. Furthermore, GCS ≤4 and NIHSS >12 are significantly associated with in-hospital mortality. Although hyponatremia is a common occurrence in patients with SICH, our study failed to show association between hyponatremia and in-hospital mortality.
Aortic Elasticity Indices as Predictors of Coronary Artery Disease Severity Assessed by SYNTAX Score
Authors: El-Naggar Heba M. , Anwar Helen S. , Helmy Hatem A. , Demitry Salwa R. 
Published: January 2022

Background:
Aortic elastic properties have been related to coronary artery disease (CAD) morbidity and mortality. We aimed to assess the relation of aortic elasticity indices to the severity and complexity of CAD assessed using the SYNTAX Score (SS), evaluating which of these indices have better predictivity for CAD severity.

Materials and Methods:
We prospectively enrolled 150 individuals who underwent elective coronary angiography for suspected CAD, out of them 29 (19.3%) had normal or nonsignificant angiographic findings (Group I), whereas 121 (80.7%) had significant CAD (Group II) for whom the SS was calculated. Echo-derived aortic elasticity indices were performed for all patients.

Results:
Logistic regression analyses showed that each of aortic distensibility, stiffness index, elastic modulus, aortic strain, and aortic peak early diastolic velocity were predictors for significant CAD and further for more complex CAD as indicated by intermediate-high SS. Receiver operator characteristic curves-derived cutoff points were performed for each of the aortic elasticity indices. Along with diabetes, decreased aortic strain ≤10.2% was the only independent predictor of intermediate-high SS (odds ratio = 4.31, 95% confidence interval = 1.38–13.50, P = 0.01).

Conclusion:
Simple M-mode derived aortic elasticity indices, particularly aortic strain ≤10.2%, might predict patients with more severe and complex CAD.
A Subtle Decline in Cardiac Mechanics is correlated with Albuminuria in Asymptomatic Normotensive Patients with Type 2 Diabetes Mellitus
Authors: Abdellatif Yasser A , Nazmy Nour Eldin M. , Bastawy Islam M. , Raafat Sameh S. 
Published: January 2022

Background:
Type 2 diabetes mellitus (T2DM) insidiously affects the myocardium with subsequent cardiomyopathy and induces microvascular damage in the kidneys reflected by albuminuria. We aimed to investigate the relationship between albuminuria and subclinical left ventricular (LV) systolic dysfunction in asymptomatic normotensive patients with T2DM assessed by two-dimensional speckle-tracking echocardiography.

Materials and Methods and Results:
Sixty normotensive patients with T2DM were included and subdivided into two subgroups, each including thirty patients according to the presence of albuminuria, together with thirty control subjects. All underwent echocardiographic examination, including LV regional and global longitudinal strain (GLS) measurements. Laboratory tests were withdrawn, including serum glycated hemoglobin (HbA1C) and albumin–creatinine ratio (ACR). When compared to the control group, patients with T2DM had a significantly lower average peak systolic LV GLS (−16.18% ± 2.78% vs. −18.13% ± 2.86%, P < 0.001), however, there was no significant difference in average peak systolic LV GLS between both diabetic subgroups (−15.57% ± 2.77% in the albuminuric subgroup vs. −16.79% ± 2.70% in the nonalbuminuric subgroup, P = 0.077). Moreover, there was a significant correlation between ACR and reduction of GLS in patients with T2DM and albuminuria (r = 0.55, P = 0.002). However, this correlation was absent in patients with T2DM without albuminuria (r = 0.107, P = 0.573).

Conclusions:
Patients with T2DM have subclinical LV systolic dysfunction with a reduction of average LV GLS that correlates with ACR in patients with T2DM and albuminuria.
Left Atrial Volume Index to Left Ventricular Ejection Fraction Ratio Predicted Major Adverse Cardiovascular Event in ST-Elevated Myocardial Infarction Patients during 8 Years of Follow-up
Authors: Yilmaz Ahmet Seyda , Kahraman Fatih , Ergül Elif , Çetin Mustafa 
Published: January 2022

Objective:
It is crucial to determine the high-risk group in ST-elevated myocardial infarction (STEMI). Left ventricle ejection fraction (LVEF) and left atrial volume index (LAVI) are the well-established parameters for risk prediction. However, major adverse cardiovascular events (MACEs) may be predicted less than actual when LVEF or LAVI are in the normal range. It was investigated LAVI to LVEF ratio (LAVI/LVEFr) for more accurate MACE prediction.

Methods:
Patients with STEMI were included in the study. LAVI and LVEF were obtained at admission. The LAVI/LVEFr was calculated as LAVI dividing by LVEF. The composite primary endpoint of the study was all-cause mortality and new-onset heart failure for 8 years follow-up.

Results:
A total of 176 patients were divided into two groups according to the presence of MACE. MACE (+) group consisted of 70 (39.7%) patients who were older and more likely to be male. While LVEF (P < 0.001) was lower, LAVI (P < 0.001) and LAVI/LVEFr (P < 0.001) were higher in MACE (+) group. Age (P = 0.003), serum creatinine (P < 0.001), and LAVI/LVEFr (P < 0.001) were independent predictors of MACE.

Conclusion:
Combined usage of LAVI and LVEF (LAVI/LVEFr), increased age, and serum creatinine level were the independent predictors of MACE during 8 years of follow-up in STEMI patients.
Assessment of Intra and Extra-Hospital Outcome after Takotsubo Syndrome in a Single-Center Population
Authors: Licordari Roberto , Manganaro Roberta , Cusmà-Piccione Maurizio , Dattilo Giuseppe , Citro Rodolfo , Khandheria Bijoy K. , Bella Gianluca Di , Zito Concetta 
Published: January 2022

Objectives:
To evaluate short- and long-term outcome in a single prospective cohort of Takotsubo syndrome (TTS) patients, trying to early identify those with better prognosis and to assess the prevalence of left ventricular ejection fraction (LVEF) recovery over time.

Methods:
Forty-nine patients prospectively enrolled underwent to assessment of demographic, clinical, and echocardiographic characteristics, and later were followed to identify the outcomes during a mean follow-up (FU) of 93 months. At the end of the FU phase, a subgroup of patients underwent to a clinical and echocardiographic re-evaluation. As major adverse cardiac events (MACE) were considered: Intra and extra-hospital death, re-hospitalizations for acute heart failure or atrial fibrillation (AF) or acute myocardial infarction (AMI) and TTS recurrence; minor events were considered minor symptoms of heart failure and angina not requiring hospitalization.

Results:
The prevalence of re-hospitalizations (MACE) over time was: 41% (n = 12) for HF; 6.8% (n = 2) for AMI; 3.4% (n = 1) for TTS relapse and 20% (n = 6) for AF. Minor events were the symptoms of chest pain and dyspnea not requiring hospitalization in 6 (20.7%) and 12 (34.4%) patients, respectively. LVEF at the time of admission was predictor for MACE. Stratifying patients on the LVEF admission median value (40%). Patients with LVEF <40% at admission had a significantly lower survival free from adverse cardiac events compared to patients with LVEF ≥40%. Twenty-seven (93%) patients underwent to a clinical reassessment with electrocardiogram and echocardiographic examination. LVEF value showed a statistically significant increase (P = 0.004) at the end of FU.

Conclusions:
At admission, “high-risk” patients (LVEF <40%) can be easily detected, allowing an appropriate pharmacological and/or mechanical support strategy and a more “careful” FU.
Prácticas de mediación de artistas y artistas-docentes en Chile. Artes relacionales como formas de enseñanza
Authors: García-Huidobro Munita María Rosario , Hoecker Gil Gabriel 
Published: January 2022

El artículo entrega parte de los resultados de un estudio que buscó comprender cómo artistas y artistas-docentes que trabajan en contextos formales e informales en Chile, vinculan la práctica artística con la pedagógica y cómo estos cruces generan propuestas en la producción artística y la educación artística. Se desarrolló una metodología cualitativa, a través de la Investigación Basada en las Artes, en donde se desarrollaron Talleres Artísticos de Discusión con grupos de artistas y artistas-docentes de diferentes regiones del país. En los resultados se muestra que artistas realizan prácticas artísticas donde se promueven elementos relacionales en la producción y en la experiencia de creación con otros/as, las cuales son prácticas mediadoras. Además, se aprecia que artistas-docentes desarrollan prácticas artísticas que son mediadoras en los contextos escolares y que a través de las artes promueven la transformación.
An analytical study about the operational effectiveness of the Covid Control Room in a Medical College of Northern India
Authors: Sehgal Shruti , Manchanda Gurdip Singh , Muzammil Khursheed , Raghav Santosh Kumar , Sehgal Shreyak 
Published: January 2022

Muzzafarnagar Medical College (MMC), Muzzafarnagar was declared a designated covid hospital by the Uttar Pradesh State Government. A Covid Control Room (CCR) was hence established to manage the disaster. Aims & Objectives: The CCR worked as the operational brain of MMC. Study Setting: Muzzafarnagar Medical College, Muzzafarnagar, Uttar Pradesh, India. Study Design: A hospital record based observational study. Material Methods: A total of 1132 admitted covid positive patients in three months constituted the study population. The CCTV cameras were installed inside the isolation wards, and the ICUs with 24/7 video coverage. The DGME (Uttar Pradesh) developed the Patient Information System (PIS) wherein information was uploaded in a database and WhatsApp messages were sent to the relatives twice daily. Results: The CCR received on an average 200 calls per day. A total of 12,622 calls were received in two months. With, PIS in function the no. of calls received in CCR reduced drastically. 100% coverage of the patients’ information was achieved. Conclusion: The scope of the control room has expanded considerably to address various aspects of the covid-19 pandemic crisis. These findings will be helpful as a reference for future. It is one of the first studies and unique in nature.
Factores asociados a disfunción sexual durante el embarazo: estudio multicéntrico en la ciudad de Medellín
Authors: Jaramillo-Saldarriaga Maria Isabel , Colonia-Toro Alejandro , Posada Gina Andrea , Uribe Maria del Pilar 
Published: January 2022

El embarazo y el parto es un período especial en la vida de la mujer, ya que tiene implicaciones físicas, hormonales y psicológicas, además de cambios sociales y culturales que pueden influir en su sexualidad. Múltiples factores se han asociado con un aumento en la frecuencia de disfunción sexual durante la gestación y el posparto, la cual puede alcanzar una incidencia hasta del 50% en estas etapas. Objetivo: Evaluar la prevalencia de disfunción sexual durante la gestación y su relación con algunos factores de riesgo y describir el comportamiento sexual de las mujeres embarazadas y postparto. Métodos: Estudio de corte transversal de pacientes embarazadas y postparto inmediato de tres centros médicos de atención obstétrica de la ciudad de Medellín. Resultados: Por medio de una encuesta personal se evaluaron 259 mujeres en embarazo y posparto en 3 diferentes centros de atención obstétrica de la ciudad de Medellín. Se encontró una prevalencia de disfunción sexual femenina del 60,2%. El tipo más frecuente de relaciones sexuales fue la vaginal (69%). El 85% de las madres y el 71,4% de los padres consideraban que existía riesgo de un posible daño al bebe con las relaciones sexuales. El 59,1% de las embarazadas recibieron información sobre sexualidad durante la gestación, siendo el 30% por parte del médico y se asoció como factor protector para disfunción sexual, junto con la estabilidad de la pareja. Como factores de riesgo se identificó el régimen subsidiado del sistema de seguridad social y la idea de daño al embarazo por parte de la madre.
Conclusión: La disfunción sexual es una entidad con una mayor prevalencia y algunas consideraciones especiales durante el embarazo, comparado con la población general. Debido a esto, los profesionales de la salud deben explorar este aspecto en la atención prenatal y brindar una adecuada información sobre la seguridad de las relaciones sexuales durante el embarazo y los posibles cambios en el deseo, el alcance del orgasmo y la satisfacción sexual.
BEA PEROLEHAN HAK ATAS TANAH DAN BANGUNAN (BPHTB)
Authors: Bonita Shavira Bonita 
Published: January 2022

Bea Perolehan Hak Atas Tanah dan Bangunan (BPHTB) ialah pajak yang dikenakan untuk setiap perolehan hak atas tanah dan bangunan di Indonesia, baik dikarenakan pemindahan hak dari orang pribadi atau badan hukum kepada orang pribadi atau badan hukum lainnya maupun pemberian hak baru oleh pemerintah atau Negara kepada orang pribadi maupun badan hukum. Penelitian ini bertujuan untuk mengetahui bagaimana pelaksanaan pemungutan BPHTB baik dalam menentukan besaran nilai, cara penyetoran, hambatan yang dihadapi dan sanksi bagi wajib pajak yang tidak membayarnya. Hambatan yang timbul biasanya diakibatkan oleh kurangnya pengetahuan wajib pajak tentang BPHTB, tidak adanya Surat Pemberitahuan Pajak Terutang (SPPT), adanya upaya untuk menghindari pajak, dan yang terakhir ialah tidak dipenuhinya kewajiban melaporkan SSB lembar ketiga ke Kantor Pelayanan Pajak Bumi dan Bangunan. Disarankan kepada pihak pihak yang bersangkutan pada pelaksanaan pemungutan pajak BPHTB di seluruh indonesia untuk mensosialisaiskan terlebih dahulu tentang pentingnya pembayaran pajak khususnya BPHTB untuk menumbuhkan kesadaran masyarakat dalam mewujudkan peran serta masyarakat dalam pembangunan. Metode penelitian yang digunakan ialah penelitian normatif yang mengunakan pendekatan perundang – undangan (statue approach) dan pendekatan konsep (conceptual approach)
ISSUE OF HOTEL TAX IN DKI JAKARTA PROVINCE
Authors: Gultom Oliver 
Published: January 2022

ABSTRAK
Pajak adalah kontribusi wajib kepada negara yang terutang oleh orang pribadi atau badan yang bersifat memaksa berdasarkan Undang-Undang, dengan tidak mendapatkan imbalan secara langsung dan digunakan untuk keperluan negara bagi sebesar-besarnya kemakmuran rakyat.
Terdapat beberapa permasalahan terkait dengan pajak yaitu kelemahan peraturan terkait perpajakan itu sendiri, lalu sosialisasi terkait peraturan pajak yang masih kurang, tingkat kesadaran wajib pajak yang kurang, pengetahuan dan tingkat ekonomi yang rendah, data yang tidak lengkap, lemahnya penegakan hukum berupa pengawasan dan sanksi yang belum konsisten dan tegas. Pada makalah ini yang menjadi permasalahan terkait pajak adalah tidak adanya pengaturan terkait suatu permasalahan khusus yang terjadi di negara Indonesia.
Solusi penyelesaian permasalahan tersebut adalah menyempurnaan peraturan atau regulasi, melakukan sosialisasi untuk menambah pengetahuan untuk menumbuhkan kesadaran wajib pajak taat pajak, meningkatkan penegakan hukum dalam pengawasan dan pemberian sanksi secara konsisten dan tegas, dan melakukan pemungutan pajak yang Adil, berdasarkan undang-undang, tidak mengganggu perekonomian, efisien dan sistemnya harus sederhana.
ABSTRACT
Tax is a mandatory contribution to the state that is owed by an individual or entity that is coercive in nature based on the law, with no direct compensation and is used for the needs of the state for the greatest prosperity of the people.
There are several problems related to taxes, namely the weakness of regulations related to taxation itself, then socialization related to tax regulations that are still lacking, the level of awareness of taxpayers is lacking, knowledge and low economic levels, databases that are not complete and accurate, weak law enforcement in the form of supervision and imposing sanctions that have not been consistent and firm. In this paper, the problem related to taxes is the absence of regulations related to a special problem that occurs in Indonesia.
The solution to solving these problems is perfecting regulations or regulations, conducting socialization to increase knowledge to raise awareness of tax-abiding taxpayers, increasing law enforcement in monitoring and imposing sanctions consistently and firmly, and conducting fair tax collection, based on the law, not disturbing economy, efficient and the system must be simple.
IDENTITY CHANGES IN CRISIS SITUATIONS. ANXIETY, FRUSTRATION AND ANGUISH DUE TO THE COVID-19 PANDEMIC
Authors: SANDU ANTONIO 
Published: January 2022

In this article, a review of the socio-anthropological literature on the impact of pandemics on the mental health of the population is made. Also, the way this pandemic affects the construction of identity of the population affected by pandemic is taken into discussion. The historical-anthropological perspective refers to the plague epidemic that affected Europe during the Middle Ages, to its psychological impact from the perspective of the individual's relationship with otherness - as a possible source of danger. The article presents a series of similarities and differences from the perspective of anguish, anxiety and frustration caused to the population by the plague pandemic and the Covid-19 pandemic, highlighting the results of studies published during 2020 in journals indexed in Web of Science, dedicated to the impact of the pandemic. of Coronavirus on the mental health of the population. The research focused on several dimensions of the social construction process of the Covid-19 pandemic, among which we mention: information on the pandemic, restrictions imposed by the authorities as elements of social
(re)construction of the limit of the human condition, medicalization of the social life and the perception of the contemporary society as a risk society. In this article we will refer exclusively to the results aimed at changes in the identity construction of people affected by the pandemic.