bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benchmarking state-of-the-art approaches for norovirus genome assembly in metagenome sample
Authors: Meleshko Dmitry , Korobeynikov Anton 
Published: July 2022

AbstractMotivationA recently published article in BMC Genomics by Fuentes-Trillo et al (2021) contains a comparison of assembly approaches of several Noroviral samples via different tools and preprocessing strategies. Unfortunately the study used outdated versions of tools as well as tools that were not designed for the viral assembly task. In order to improve the suboptimal assemblies the authors suggested different sophisticated preprocessing strategies that seem to make only minor contributions to the results. We redone the analysis using state-of-the art tools designed for viral assembly.ResultsHere we demonstrate that tools from the SPAdes toolkit (rnaviralSPAdes and coronaSPAdes) allows one to assemble the samples from the original study into a single contig without any additional preprocessing.
Cortical Parvalbumin-positive Interneuron Development and Function are Altered in the APC Conditional Knockout Mouse Model of Infantile Spasm Syndrome
Authors: Ryner Rachael F. , Derera Isabel D. , Armbruster Moritz , Kansara Anar , Sommer Mary E. , Pirone Antonella , Noubary Farzad , Jacob Michele , Dulla Chris G. 
Published: July 2022

AbstractInfantile Spasms syndrome (ISS) is a childhood epilepsy syndrome characterized by infantile or late onset spasms, abnormal neonatal EEG, and epilepsy. Few treatments exist for IS, clinical outcomes are poor, and the molecular and circuit-level etiologies of IS are not well understood. Multiple human ISS risk genes are linked to Wnt/β-catenin signaling, a pathway which controls developmental transcriptional programs and promotes glutamatergic excitation via β-catenin’s role as a synaptic scaffold. We previously showed that deleting adenomatous polyposis coli (APC), a component of the β-catenin destruction complex, in excitatory neurons (APC cKO mice, APCfl/fl x CaMKIIαCre) in mice increased β-catenin levels in developing glutamatergic neurons and led to infantile behavioral spasms, abnormal neonatal EEG, and adult epilepsy. Here, we tested the hypothesis that the development of inhibitory GABAergic interneurons (INs) is disrupted in APC cKOs. IN dysfunction is implicated in human ISS, is a feature of other rodent models of ISS and may contribute to the manifestation of spasms and seizures. We found that parvalbumin positive INs (PV+INs), an important source of cortical inhibition, were decreased in number, underwent disproportionate developmental apoptosis, and had altered dendrite morphology at P9, the peak time of behavioral spasms. PV+INs received excessive excitatory input and their intrinsic ability to fire action potentials was reduced at all timepoints examined (P9, P14, P60). Subsequently, synaptic inhibition of pyramidal neurons was uniquely altered in the somatosensory cortex of APC cKO mice at all ages, with both decreased inhibition at P14 and enhanced inhibition at P9 and P60. These results indicate that inhibitory circuit dysfunction occurs in APC cKOs and, along with known changes in excitation, may contribute to ISS-related phenotypes.Significance StatementInfantile spasms syndrome (ISS) is a devastating epilepsy with limited treatment options and poor clinical outcomes. The molecular, cellular, and circuit disruptions that cause infantile spasms and seizures are largely unknown, but inhibitory GABAergic interneuron dysfunction has been implicated in rodent models of ISS and may contribute to human ISS. Here, we utilize a rodent model of ISS, the APC cKO mouse, in which β-catenin signaling is increased in excitatory neurons. This results in altered parvalbumin-positive GABAergic interneuron development and inhibitory synaptic dysfunction throughout life, showing that pathology arising in excitatory neurons can initiate long-term interneuron dysfunction. Our findings further implicate GABAergic dysfunction in ISS, even when pathology is initiated in other neuronal types.
Linking supervisors’ bottom-line mentality to workplace cheating behavior: examining the mediating and moderating role of organizational cynicism and moral identity
Authors: Farasat Mobina , Azam Akbar , Imam Hassan , Hassan Hamid 
Published: July 2022

PurposeThe purpose of this study is to examine how and when supervisors’ bottom-line mentality (BLM) influences workplace cheating behavior. Specifically, the authors draw upon social exchange theory (Blau, 1964) and the negative reciprocity norm (Gouldner, 1960) argument, to explain that supervisor BLM is likely related to organizational cynicism and subsequently those employees may engage in cheating behavior as a way to make things even with the organization. Furthermore, the authors theorized that organizational cynicism and supervisors’ BLM via organizational cynicism, increase cheating behavior among employees with a weak moral identity.Design/methodology/approachTo test the current model, the authors collected data from 232 employees working in various Pakistani firms.FindingsThe results affirmed the authors’ moderated-mediation model. The positive indirect effects of supervisors’ BLM on workplace cheating behavior, through organizational cynicism, are moderated by employees’ moral identity.Originality/valueThis is the first study that examine the mediating and moderating role of organizational cynicism and employees’ moral identity in the relationship between supervisors’ BLM and workplace cheating behavior.
Early detection of human-related risks in an increasingly digitized work environment
Authors: Dubosson Magali , Fragnière Emmanuel , Meier Samuele 
Published: July 2022

PurposeHuman-related risks are practices in a given organization that lead to harmful behaviors that prevent managers and their teams from achieving goals. The purpose of this article is to enable the organization to provide a preventive and simple response to risks in the event that deterioration in employee well-being is detected.Design/methodology/approachIn the literature, many questionnaires based on a variety of metrics have been developed and tested to measure and assess the quality of work life (e.g. stress, commitment, satisfaction, etc.). The approach of this study was to identify the most meaningful items and combine them into a unique score integrated into an effective decision-making module.FindingsA long process of trial and error was necessary to collect confidential information from employees, both anonymously and longitudinally, to measure well-being in the workplace objectively and globally. The unique score generated provides an indication of potential human risk.Research limitations/implicationsThis research and its practical implementation have demonstrated the importance of personal-data protection and the need to work harder to maintain employees' digital trust while using a digitized tool.Practical implicationsDevelopment of a new app that was used for the first time to regularly assess ill-being in several companies.Social implicationsThe social implication of this research is to contribute to health policies related to well-being in the workplace.Originality/valueTo the authors’ knowledge, this is the first time that a software module measuring the human risk of an entire company has been embedded in Enterprise Risk Management (ERM).
Information system assisted knowledge accounting and cognitive managerial implications
Authors: Karagiorgos Alkiviadis , Lazos Grigorios , Stavropoulos Antonios , Karagiorgou Dimitra , Valkani Fani 
Published: July 2022

PurposeThis paper examines issues that focus on the importance of accounting data generated knowledge information and its role in modern business. The cognitive aspect of this research reflects the ability of companies and its employees to apply knowledge for managerial purposes using accounting data.Design/methodology/approachUsing a questionnaire, a five-factor model related to information communication, information cognitive utilization, functional optimization, applicability and cognitive efficiency was created.FindingsFindings present a series of complex correlations highlighting possible actions to utilize knowledge as a tool for management. Information is obtained regarding the management of knowledge and the adoption of information systems.Research limitations/implicationsThe results reflect the limited implementation of intellectual capital practices and understanding of knowledge as a financial tool for executives and employees. Based on the above, an attempt was made to formulate the questions for the careful identification of the factors.Practical implicationsRapid developments in information and communication technologies, together with a realization that knowledge is a resource of general and cost strategic importance, changed the operational structures of companies, shifting value from materials to intangible assets. This paper demonstrates how multiple variables are correlated and how small changes could help increase intellectual capital and facilitate the construction of knowledge based systems.Social implicationsThe need for an accounting valuation of intellectual capital in order to present the true picture of business value is evident. This paper illustrates factors such as interactive communication and systematic cognitive efficiency or the monetization of information as a preliminary step for future valuation and management intellectual capital models.Originality/valueDirect access to sufficient and reliable information, lead to the search for effective tools for the creation, aggregation and exchange of knowledge. The latter becomes a key goal for information systems. Emphasis is placed on the benefits and critical success factors of knowledge management systems, as essential information systems to support and enhance organizational processes.
Lean supply chain management and Industry 4.0 interrelationships: the status quo and future perspectives
Authors: El Jaouhari Asmae , Arif Jabir , Fellaki Soumaya , Amejwal Mohamed , Azzouz Khaoula 
Published: July 2022

Purpose
This study aims to address Industry 4.0 (I4.0) technologies that can improve the research and implementation of lean supply chain management (LSCM) and the enhanced LSCM subfields in I4.0 technologies.

Design/methodology/approach
The authors conducted a systematic literature review to detect, categorize and assess recent data, highlighting patterns and providing suggestions for potential research in this field, to investigate I4.0 literature and its effect on LSCM. The authors examined 79 published types of research from the Scopus database that were published between 2010 and 2021 and classified them into four LSCM fields: logistics, production, supply chain and marketing.

Findings
The authors can emphasize the fact that the literature on this topic is in progress, from early German academic research to the current creation of new effects around the world. The majority of the potential effects investigated were discovered to improve specific areas that ultimately enhance the practices of the four LSCM domains as well as performance outcomes. The authors were also able to assess the extent to which present and upcoming I4.0 technologies can improve LSCM research and implementation.

Originality/value
To the best of the authors’ knowledge, this is the first study of its kind. Although some research looked into various areas of I4.0 and LSCM topics, there has been no research specifically looking into the impact of I4.0 on LSCM. The originality of this study lies in the treatment of the main fields and sub-fields of LSCM, which can benefit from the technologies of I4.0. Academic scholars interested in the research topics may benefit from the findings of this study. Organizations in various industrial sectors, particularly manufacturing, where lean thinking is used, business professionals specialized in lean operations and supply chain management, along with anyone else who wants to learn more about the interrelationships between I4.0 and LSCM.
Parental roles, financial literacy and budgeting behaviour: a survey during the COVID-19 pandemic
Authors: Phung Trang M.T. 
Published: July 2022

PurposeThis study aims to provide evidence on the importance of parental financial heads in the family in promoting students' financial literacy levels and budgeting habits.Design/methodology/approachUsing survey data on 730 college students in Vietnam, this study investigated the relationship between parental financial heads, students' financial literacy and budgeting habits. Multiple regression and logit function are the primary approaches in the study.FindingsThis study found a positive association between parental head roles and students' financial literacy and budgeting habits after controlling for demographics. Students whose parents are primarily responsible for financial decisions in the family perform higher in financial literacy and make a budget more frequently. The results are robust to alternative approaches.Practical implicationsThis study’s results help parents, especially mothers who are often more vulnerable in the family, better understand the important role of being the financial deciders in the family and how this can increase their children's financial literacy and help their children manage money more effectively.Originality/valueThis is the first study to address the importance of parents' head roles in enhancing students' financial literacy and budgeting behaviour.
Chronic alcohol consumption alters home‐cage behaviors and responses to ethologically relevant predator tasks in mice
Authors: Neira Sofia , Hassanein Leslie A. , Stanhope Christina M. , Buccini Michelle C. , D'Ambrosio Shannon L. , Flanigan Meghan E. , Haun Harold L. , Boyt Kristen M. , Bains Jaideep S. , Kash Thomas L. 
Published: July 2022

AbstractBackgroundAlcohol withdrawal is a key component of severe alcohol use disorder. Animal models of alcohol withdrawal tend to focus on traditional anxiety/stress tests. While these have been essential to advancing our understanding of the biology of alcohol withdrawal, abrupt cessation of drinking following heavy alcohol consumption can also trigger withdrawal‐related affective states that impact responses to a variety of life events and stressors. To this end, we show that behaviors in a variety of tasks that differ in task demand and intensity are altered during withdrawal in male and female mice after voluntary alcohol access.MethodsMale and female miceunderwent six weeks of intermittent two‐bottle choice alcohol exposure followed by behavioral tests. The tests included—Home cage: low‐stress baseline environment to measure spontaneous natural behaviors; Open field: anxiety‐inducing bright novel environment; Looming disc: arena with a protective hut where mice are exposed to a series of discs that mimic an overhead advancing predator, and Robogator‐simulated predator task: forced foraging behavioral choice in the presence of an advancing robot predator that “attacks” when mice are near a food pellet in a large open arena.ResultsA history of alcohol exposure impacted behaviors in these tasks in a sex‐dependent manner. In the home cage, alcohol induced reductions in digging and heightened stress coping through an increase in grooming time. In males, increased rearing yielded greater vigilance/exploration in a familiar environment. The open‐field test revealed an anxiety phenotype in both male and female mice exposed to alcohol. Male mice showed no behavioral alterations to the looming disc task, while females exposed to alcohol showed greater escape responses than water controls, indicative of active stress‐response behaviors. In males, the Robogator task revealed a hesitant/avoidant phenotype in alcohol‐exposed mice under greater task demands.ConclusionsFew drugs show robust evidence of efficacy in clinical trials for alcohol withdrawal. Understanding how withdrawal alters a variety of behaviors in both males and females that are linked to stress coping can increase our understanding of alcohol misuse and aid in developing better medications for treating individuals with AUD.
Internal capital allocation in IPOs and corporate innovation: The moderating role of political connections
Authors: Tang Jinghua , Liu Qigui 
Published: July 2022

AbstractWe explore the effect of initial public offering (IPO) capital allocation on corporate innovation. We document that IPOs enhance corporate innovation through allocation of internal capital to innovative projects. While political connections moderate the IPO‐innovation relation in that connected firms allocate less IPO capital to innovative projects and are more likely to reallocate their resource from innovative to non‐innovative projects. Resource allocation to innovative projects results in better post‐IPO performance, especially in non‐connected firms. Overall, this study identifies intra‐firm capital allocation as an important factor that contribute to firm innovation and the distortion of resource allocation linked to political ties.
First detection and eradication of a structural infestation by western drywood termite, Incisitermes minor (Hagen) (Isoptera: Kalotermitidae), in Australia
Authors: Horwood Martin , Lo Nathan 
Published: July 2022

AbstractThe western drywood termite, Incisitermes minor, is one of the most economically damaging termites in the United States of America. Although native to the southwestern USA and northwestern Mexico, it has spread widely across the USA and to other countries including China and Japan. The first structural infestation by I. minor in Australia was detected in the timber roofing of a house in Sydney, NSW, in July 2019. Imported exotic timbers, including Douglas fir from the USA, installed approximately 20 years prior to the detection, were the likely source of the infestation. Measures undertaken to eradicate I. minor were (1) ‘tent’ fumigation of the house with sulphuryl fluoride; (2) trap deployment for termite alates; and (3) delimiting surveillance in nearby homes. No I. minor termites were detected outside the infested premises. The haplotype observed by way of DNA sequencing was similar to those of I. minor specimens collected from Louisiana, USA, and Japan. Given the potential economic impacts of I. minor, should it establish in Australia, along with other drywood termites, especially West Indian drywood termite, Cryptotermes brevis, government biosecurity organisations should devote more resources to the design and implementation of drywood termite management systems for new and existing buildings.
The Turkish version of the Camberwell Assessment of Need for the Elderly: A validity and reliability study
Authors: Güzel Aysun 
Published: July 2022

AbstractObjectivesThe present study attempted to adapt and validate the Turkish version of the Camberwell Assessment of Need for the Elderly (CANE‐T).MethodsThe data of this methodological study were collected from 610 older people who volunteered between September 10 and December 15, 2019. The SPSS 20 and LISREL software were used to perform reliability (internal reliability, parallel forms reliability/equivalent forms, and test–retest reliability) and validity (exploratory factor analysis and confirmatory factor analysis) analyses for the CANE‐T.ResultsThe Kaiser–Meyer–Olkin test revealed the sampling adequacy to be 0.72. After deleting four items (psychological distress, behavior, alcohol, and money) with a factor loading below 0.30 from the dataset, it was found that the scores on the scale explained 55% of the total variance. Besides, the confirmatory factor analysis revealed the following fit indices: p < 0.05, root mean square error of approximation (RMSEA) = 0.08, root mean square residuals (RMR) = 0.07, standardized root mean square residual (SRMR) = 0.07, goodness‐of‐fit index (GFI) = 0.88, and adjusted goodness‐of‐fit index (AGFI) = 0.84. Concerning reliability, Cronbach's α values were calculated to be 0.78 for ‘Physical Needs’, 0.74 for ‘Psychophysiological Needs’, 0.75 for ‘Security Needs’, 0.75 for ‘Social Needs’, and 0.75 for ‘Health Needs’.ConclusionsOverall, it was concluded that the 20‐item five‐factor CANE‐T is a valid and reliable tool to measure the needs of older adults in the Turkish context.
A prospective cohort study comparing neonatal outcomes of waterbirth and land birth in an Australian tertiary maternity unit
Authors: Seed Emma , Kearney Lauren , Weaver Edward , Ryan Elizabeth G. , Nugent Rachael 
Published: July 2022

BackgroundMaternal preference for warm water immersion (WWI) and waterbirth is increasing, but adoption into obstetric guidelines and clinical practice remains limited. Concerns regarding safety and a paucity of evidence have been cited as reasons for the limited adoption and uptake.AimThe aim was to investigate maternal and neonatal outcomes after WWI and/or waterbirth compared with land birth.Materials and methodsA prospective cohort study was conducted in an Australian public maternity hospital between 2019 and 2020. Maternal and neonatal outcomes for 1665 women who had a vaginal birth were studied.Primary outcome was admission to the neonatal unit (NNU). Secondary outcomes included neonatal antibiotic administration, maternal intrapartum fever, epidural use and perineal injury. Multivariate logistical regression analyses compared the outcomes between three groups: waterbirth, WWI only and land birth.ResultsNNU admissions for a suspected infectious condition were significantly higher in the land birth group (P = 0.035). After accounting for labour duration, epidural use and previous birth mode, no significant difference was detected between groups in the odds of NNU admission (P = 0.167). No babies were admitted to NNU with water inhalation or drowning. Women birthing on land were more likely to be febrile (2 vs 0%; P = 0.007); obstetric anal sphincter injury and postpartum haemorrhage were similar between groups. Regional analgesia use was significantly lower in the WWI group compared to the land birth group (21.02 vs 38.58%; P = <0.001). There was one cord avulsion in the waterbirth group (0.41%).ConclusionMaternal and neonatal outcomes were similar between groups, with no increased risk evident in the waterbirth and WWI groups.