bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of a broad-side coupling modal filter by evolutionary strategy algorithm with setting the ranges of the optimization parameters
Authors: Gordeyeva V O , Belousov A O 
Published: July 2022

Abstract
The paper considers the optimization of a modal filter with broad-side coupling by evolutionary strategy algorithm with limitations (i.e., setting the ranges of the optimization parameters). An improved block diagram of the algorithm with limitations is presented. The sequential optimization that uses the original and improved algorithms with different numbers of computations is performed. The performance of the improved algorithm is demonstrated. The main advantages and disadvantages of this algorithm are shown.
Studying the process of holographic formation of multilayer inhomogeneous PPM-LC diffraction structures
Authors: Ivanchenko V G , Dolgirev V O , Rastrygin D S , Sharangovich S N 
Published: July 2022

Abstract
The article describes a theoretical model for the formation of a multilayer diffractive holographic structure (MIHDS) based on a photopolymer composition including liquid crystals (LC). We presented mathematical modeling of spatial profiles kinetics of the refractive index of the first harmonic of MIHDS considering the photoinduced light absorption (PLA) of the non-optimized and optimized composition. Numerical modeling has shown that optimization of the composition of MIHDS at different thicknesses of the diffraction layer requires a difference in the concentration of the dye-sensitizer for subsequent layers.
Power supply output inductance effect on arc parameters of high-power impulse magnetron sputtering
Authors: Oskirko V O , Pavlov A P , Zakharov A Z , Semenov V A , Azhgikhin M I , Solovyev A A 
Published: July 2022

Abstract
The paper studies the influence of the power supply output inductance on the arc parameters, which form on the sputtered target surface during high-power impulse magnetron sputtering. The arc energy, lifetime and maximum current are measured by the up-to-date power source and the proposed arc simulation circuit at various output inductance values. The experimental data are compared with the simulation results. The paper presents a brief model description for the arc parameter calculations. According to the experimental data, the decrease in the output inductance leads to the increase in the peak current, arc lifetime and energy. It is shown that the energy recuperation stored in the output inductance allows reducing the arc energy. Also, self-locking of control transistor occurs at a lower value (∼1 µH) of the output inductance, leading to the reduction in the current amplitude and the additional decrease in the arc energy.
Electron-beam modification of nitrile butadiene rubber in the fore-vacuum pressure range
Authors: Yushkov Yu G , Kazakov A V , Tyunkov A V 
Published: July 2022

Abstract
We have studied the modification of nitrile butadiene rubber surface properties by pulsed and by continuous electron beams generated in inert (argon, helium) and in chemically active (oxygen, nitrogen, air) gas atmosphere in the fore-vacuum range of pressure (∼10 Pa). Relative measurements of the wear rate, friction coefficient, and contact (wetting) angle of the sample surfaces before and after beam treatment have been made. We have found that the electron-beam treatment of nitrile butadiene rubber does not result in any significant thermal damage to its surface, and that dependencies of the coefficient of friction and the wear rate on the surface treatment duration have a non-monotonic character. For optimal electron beam treatment conditions, the friction coefficient decreases by a factor of about two.
3D biomaterial P scaffolds carrying umbilical cord mesenchymal stem cells improve biointegration of keratoprosthesis
Authors: Li Yueyue , Xu Wenqin , Li Qian , Li Xiaoqi , Li Junyang , Kang Li , Fang Yifan , Cheng Shuaishuai , Zhao Peng , Jiang Shumeng , Liu Wei , Yan Xiaojun , Du Yanan , Wang Liqiang , Huang Yifei 
Published: July 2022

Abstract
Biointegration of a keratoprosthesis (KPro) is critical for the device stability and long-term retention. Biointegration of the KPro device and host tissue takes place between the surrounding corneal graft and the central optic (made by poly (methyl methacrylate)). Our previous clinical results showed that auricular cartilage reinforcement is able to enhance the KPro biointegration. However, the auricular cartilage is non-renewable and difficult to acquire. In this study, we developed a novel type of biomaterial using a three-dimensional porous polyethylene glycol acrylate scaffold (3D biological P-scaffold) carrier with chondrocytes differentiated from induced human umbilical cord mesenchymal stem cells (hUC-MSCs) and tested in rabbit corneas. The results showed hUC-MSCs bear stem cell properties and coule be induced into chondrocytes, P-scaffold is beneficial to the growth and differentiation of hUC-MSCs both in vivo and in vitro. Besides, after implanting the P-scaffold into the corneal stroma, no serious immune rejection response, such as corneal ulcer or perforation were seen, suggested a good biocompatibility of P-scaffold with the corneal tissue. Moreover, after implanting P-scaffold in together with the differentiated chondrocytes into the rabbit corneal stroma, they significantly increased corneal thickness and strengthened the host cornea, and chondrocytes could stably persist inside the cornea. In summary, the 3D biological P-scaffold carrying differentiated hUC-MSCs could be the preferable material for KPro reinforcement.
The SAGEX review on scattering amplitudes Chapter 5: Analytic bootstraps for scattering amplitudes and beyond
Authors: Papathanasiou Georgios 
Published: July 2022

Abstract
One of the main challenges in obtaining predictions for collider experiments from perturbative quantum field theory, is the direct evaluation of the Feynman integrals it gives rise to. In this chapter, we review an alternative bootstrap method that instead efficiently constructs physical quantities by exploiting their analytic structure. We present in detail the setting where this method has been originally developed, six- and seven-particle amplitudes in the large-color limit of

N
=
4

super Yang–Mills theory. We discuss the class of functions these amplitudes belong to, and the strong clues mathematical objects known as cluster algebras provide for rendering this function space both finite and of relatively small dimension at each loop order. We then describe how to construct this function space, as well as how to locate the amplitude inside of it with the help of kinematic limits, and apply the general procedure to a concrete example: the determination of the two-loop correction to the first nontrivial six-particle amplitude. We also provide an overview of other areas where the realm of the bootstrap paradigm is expanding, including other scattering amplitudes, form factors and Feynman integrals, and point out the analytic properties of potentially wider applicability that it has revealed.
Morphisms and automorphisms of skew-symmetric Lotka–Volterra systems*
Authors: Evripidou C A , Kassotakis P , Vanhaecke P 
Published: July 2022

Abstract
We study the basic relation between skew-symmetric Lotka–Volterra (LV) systems and graphs, both at the level of objects and morphisms, and derive a classification from it of skew-symmetric LV systems in terms of graphs as well as in terms of irreducible weighted graphs. We also obtain a description of their automorphism groups and of the relations which exist between these groups. The central notion introduced and used is that of decloning of graphs and of LV systems. We also give a functorial interpretation of the results which we obtain.
Raman imaging of twist angle variations in twisted bilayer graphene at intermediate angles
Authors: Schäpers A , Sonntag J , Valerius L , Pestka B , Strasdas J , Watanabe K , Taniguchi T , Wirtz L , Morgenstern M , Beschoten B , Dolleman R J , Stampfer C 
Published: July 2022

Abstract
Van der Waals layered materials with well-defined twist angles between the crystal lattices of individual layers have attracted increasing attention due to the emergence of unexpected material properties. As many properties critically depend on the exact twist angle and its spatial homogeneity, there is a need for a fast and non-invasive characterization technique of the local twist angle, to be applied preferably right after stacking. We demonstrate that confocal Raman spectroscopy can be utilized to spatially map the twist angle in stacked bilayer graphene for angles between 6.5∘ and 8∘ when using a green excitation laser. The twist angles can directly be extracted from the moiré superlattice-activated Raman scattering process of the transverse acoustic (TA) phonon mode. Furthermore, we show that the width of the TA Raman peak contains valuable information on spatial twist angle variations on length scales below the laser spot size of ∼500 nm.
Relationships between trunk radial growth and fruit yield in apple and pear trees on size-controlling rootstocks
Authors: Plavcová Lenka , Mészáros Martin , Šilhán Karel , Jupa Radek 
Published: July 2022

AbstractBackground and AimsUnderstanding the mutual co-ordination of vegetative and reproductive growth is important in both agricultural and ecological settings. A competitive relationship between vegetative growth and fruiting is often highlighted, resulting in an apparent trade-off between structural growth and fruit production. However, our understanding of factors driving this relationship is limited.MethodsWe used four scions grafted onto a series of size-controlling rootstocks to evaluate the relationships between the annual fruit yield and radial growth of trunks, branches and roots. To assess tree radial growth, we measured ring widths on extracted tree cores, which is an approach not frequently used in a horticultural setting.Key ResultsWe found that the yield and radial growth were negatively related when plotted in absolute terms or as detrended and normalized indices. The relationship was stronger in low vigour trees, but only after the age-related trend was removed. In contrast, when trunk radial growth was expressed as basal area increment, the negative relationship disappeared, suggesting that the relationship between trunk radial growth and fruit yield might not be a true trade-off related to the competition between the two sinks. The effect of low yield was associated with increased secondary growth not only in trunks but also in branches and roots. In trunks, we observed that overcropping was associated with reduced secondary growth in a subsequent year, possibly due to the depletion of reserves.ConclusionsOur results show that variation in annual fruit yield due to tree ageing, weather cueing and inherent alternate bearing behaviour is reflected in the magnitude of secondary growth of fruit trees. We found little support for the competition/architecture theory of rootstock-induced growth vigour control. More broadly, our study aimed at bridging the gap between forest ecology and horticulture.
Multicenter Pivotal Study Demonstrates Safety and Efficacy of a New Cellulite Procedure: 3-Month Results
Authors: Stevens W Grant , Green Jeremy B , Layt Craig , Kaminer Michael S , Harrington Jennifer , Fan Larry , Wall Holly , Fabi Sabrina , Magnusson Mark R 
Published: July 2022

Abstract

Background
Cellulite is an aesthetic condition affecting the appearance of skin in certain body regions and is associated with body dissatisfaction, psychosocial stress, and decreased quality of life. Previous studies established the safety and feasibility of a novel, minimally invasive device to identify and release septa responsible for cellulite depressions: targeted verifiable subcision (TVS).

Objectives
The objective of this single-arm, open-label, multicenter study was to evaluate the safety and efficacy of TVS for reducing the appearance of moderate to severe cellulite in adult women.

Methods
Adult women aged 21 to 55 years and a BMI &lt; 30 kg/m2 with moderate or severe cellulite on the buttocks and/or thighs were eligible to enroll at 9 sites. Endpoint data included results from 4 of the postprocedural follow-up visits at 24 hours, 7 days, 30 days, and 90 days. The primary endpoints were a mean ≥1 point reduction in the Cellulite Severity Scale at 90 days and no related serious adverse events at 30 days.

Results
Seventy-four female participants with a mean BMI of 24.8 ± 2.7 and age of 41.4 ± 7.4 years received this single procedure. The mean improvement in Cellulite Severity Scale (N = 68) was 1.5 ± 0.9 (P &lt; 0.0001). There were no device-related serious adverse events at 30 days.

Conclusions
TVS for selectively identifying and verifiably releasing septa responsible for cellulite depressions is an effective and safe means to improve the appearance of moderate to severe cellulite in adult women.

Level of Evidence: 2
Hiplot: a comprehensive and easy-to-use web service for boosting publication-ready biomedical data visualization
Authors: Li Jianfeng , Miao Benben , Wang Shixiang , Dong Wei , Xu Houshi , Si Chenchen , Wang Wei , Duan Songqi , Lou Jiacheng , Bao Zhiwei , Zeng Hailuan , Yang Zengzeng , Cheng Wenyan , Zhao Fei , Zeng Jianming , Liu Xue-Song , Wu Renxie , Shen Yang , Chen Zhu , Chen Saijuan , Wang Mingjie ,   Hiplot Consortium
Published: July 2022

Abstract
Complex biomedical data generated during clinical, omics and mechanism-based experiments have increasingly been exploited through cloud- and visualization-based data mining techniques. However, the scientific community still lacks an easy-to-use web service for the comprehensive visualization of biomedical data, particularly high-quality and publication-ready graphics that allow easy scaling and updatability according to user demands. Therefore, we propose a community-driven modern web service, Hiplot (https://hiplot.org), with concise and top-quality data visualization applications for the life sciences and biomedical fields. This web service permits users to conveniently and interactively complete a few specialized visualization tasks that previously could only be conducted by senior bioinformatics or biostatistics researchers. It covers most of the daily demands of biomedical researchers with its equipped 240+ biomedical data visualization functions, involving basic statistics, multi-omics, regression, clustering, dimensional reduction, meta-analysis, survival analysis, risk modelling, etc. Moreover, to improve the efficiency in use and development of plugins, we introduced some core advantages on the client-/server-side of the website, such as spreadsheet-based data importing, cross-platform command-line controller (Hctl), multi-user plumber workers, JavaScript Object Notation-based plugin system, easy data/parameters, results and errors reproduction and real-time updates mode. Meanwhile, using demo/real data sets and benchmark tests, we explored statistical parameters, cancer genomic landscapes, disease risk factors and the performance of website based on selected native plugins. The statistics of visits and user numbers could further reflect the potential impact of this web service on relevant fields. Thus, researchers devoted to life and data sciences would benefit from this emerging and free web service.
gofasta: command-line utilities for genomic epidemiology research
Authors: Jackson Ben 
Published: July 2022

AbstractSummarygofasta comprises a set of command-line utilities for handling alignments of short assembled genomes in a genomic epidemiology context. It was developed for processing large numbers of closely related SARS-CoV-2 viral genomes and should be useful with other densely sampled pathogen genomic datasets. It provides functions to convert sam-format pairwise alignments between assembled genomes to fasta format; to annotate mutations in multiple sequence alignments, and to extract sets of sequences by genetic distance measures for use in outbreak investigations.Availability and implementationgofasta is an open-source project distributed under the MIT license. Binaries are available at https://github.com/virus-evolution/gofasta, from Bioconda, and through the Go programming language’s package management system. Source code and further documentation, including walkthroughs for common use cases, are available on the GitHub repository.
Advances in studying human gametogenesis and embryonic development in China
Authors: Liu Qiang , Chen Xi , Qiao Jie 
Published: July 2022

AbstractReproductive medicine in China has developed rapidly since 1988 due to support from the government and scientific exploration. However, the success rate of assisted reproduction technology is around 30–40% and many unknown “black boxes” in gametogenesis and embryo development are still present. With the development of single-cell and low-input sequencing technologies, the network of transcriptome and epigenetic regulation (DNA methylation, chromatin accessibility, and histone modifications) during the development of human primordial germ cells, gametes, and embryos has been investigated in depth. Furthermore, preimplantation genetic testing has also rapidly developed. In this review, we summarize and analyze China’s outstanding progress in these fields.
Introduction: Global TV Images of Female Masculinity in the 2010s
Authors: Zhao Jamie J , Ng Eve 
Published: July 2022

Abstract
This introductory article to the special Forum “Global TV Images of Female Masculinity in the 2010s” offers a reflection on the concept of “female masculinity” in global media and gender studies. Witnessing a growing number of TV representations of masculine girls and women worldwide, we present a summary of the four articles which comprise this themed Forum and address a number of key issues in their case studies, including televisual imaginaries of heterosexual, masculine women, the cultural legitimization of global female masculinities on reality TV, and the racialization and stigmatization of masculine women in White heteronormative societies. The Forum thus promotes a critical dialogue that aims to stimulate further interest in this interdisciplinary field by emphasizing the mutual implications of gendered TV genres and tropes, cross-cultural currents of gender, sexual, and racial knowledge and politics, and the intersectionality of female gender, sexuality, race, and nationality in TV representations.
Loading Cost-Aware Model Caching And Request Routing In Edge-enabled Wireless Sensor Networks
Authors: Yao Mianyang , Chen Long , Wu Yalan , Wu Jigang 
Published: July 2022

Abstract
Existing works on caching in multi-access edge computing focus on service caching and request routing. However, loading cost and execution time influenced by resource sharing have not been well exploited. To fill this gap, we investigate the joint optimization problem over deep neural network (DNN) model caching and DNN request routing with edge collaboration in edge-enabled wireless sensor networks. A problem is formulated, with the objective of maximizing throughput, under constraints of budget, accuracy and latency etc. The proof of NP-hardness for the formulated problem is provided. To solve the problem, an approximation algorithm based on randomized rounding is presented. In addition, the approximation ratio for the presented algorithm is proved to be $1/(1-\sqrt{4\ln S/\xi^\dagger})$, where $S$ is the number of edge servers and $\xi^\dagger$ is the objective value from linear relaxation. Extensive experiments demonstrate that the system throughput for the presented algorithm can be improved by 58.8% on average, compared with that of the baseline algorithm.
Multi-omics molecular biomarkers and database of osteoarthritis
Authors: Li Jianhua , Yang Xiaotian , Chu Qinjie , Xie Lingjuan , Ding Yuwen , Xu Xiaoxu , Timko Michael P , Fan Longjiang 
Published: July 2022

AbstractOsteoarthritis (OA) is the most common form of arthritis in the adult population and is a leading cause of disability. OA-related genetic loci may play an important role in clinical diagnosis and disease progression. With the rapid development of diverse technologies and omics methods, many OA-related public data sets have been accumulated. Here, we retrieved a diverse set of omics experimental results from 159 publications, including genome-wide association study, differentially expressed genes and differential methylation regions, and 2405 classified OA-related gene markers. Meanwhile, based on recent single-cell RNA-seq data from different joints, 5459 cell-type gene markers of joints were collected. The information has been integrated into an online database named OAomics and molecular biomarkers (OAOB). The database (http://ibi.zju.edu.cn/oaobdb/) provides a web server for OA marker genes, omics features and so on. To our knowledge, this is the first database of molecular biomarkers for OA.
Effects of cannabis on congenital limb anomalies in 14 European nations: A geospatiotemporal and causal inferential study
Authors: Reece Albert Stuart , Hulse Gary Kenneth 
Published: July 2022

Abstract
Cannabinoid exposure is increasing in some European nations. Europe therefore provides an interesting test environment for the recently reported link between cannabis exposure and congenital limb anomaly (CLA) rates (CLARs). Exponential genotoxic dose–response relationships make this investigation both intriguing and imperative. Annual CLAR in 14 nations were from Epidemiological Surveillance of Congenital Anomalies. Drug use rates were from European Monitoring Centre for Drugs and Drug Dependency. Median household income was from the World Bank. E-values provide a quantitative measure of robustness of results to confounding by extraneous covariates. Inverse probability weighting is an important technique for equalizing exposures across countries and removing sources of bias. Rates of CLA, hip dysplasia and the whole group of limb anomalies were higher in countries with increasing daily cannabis use (P = 1.81 × 10−16, 0.0005 and 2.53 × 10−6, respectively). In additive inverse-probability-weighted panel models, the limb reduction-resin Δ9-tetrahydrocannabinol (THC) concentration E-value estimate was 519.93 [95% lower bound (mEV) 49.56], order Resin &gt; Herb ≫ Tobacco &gt; Alcohol. Elevations were noted in 86% E-value estimates and 70.2% of mEVs from 57 E-value pairs from inverse-probability-weighted panel models and from spatial models. As judged by the mEV the degree of association with metrics of cannabis exposure was hip dysplasia &gt; polydactyly &gt; syndactyly &gt; limb anomalies &gt; limb reductions with median E-value estimates from 3.40 × 1065 to 7.06 and median mEVs from 6.14 × 1033 to 3.41. Daily cannabis use interpolated was a more powerful metric of cannabis exposure than herb or resin THC exposure. Data indicate that metrics of cannabis exposure are closely linked with CLAR and satisfy epidemiological criteria for causality. Along with Hawaii and the USA, Europe now forms the third international population in which this causal link has been demonstrated. Cannabis as a predictor of limb anomalies was more potent than tobacco or alcohol. Cannabinoid access should be restricted to protect public health and the community genome/epigenome transgenerationally.