bluuebunny/crossref_metadata_2025_split huggingface dataset:
Training peer recovery specialists in behavioral activation: preliminary outcomes and predictors of competence
Authors: Anvari Morgan S. , Kleinman Mary B. , Dean Dwayne , Rose Alexandra L. , Bradley Valerie D. , Hines Abigail C. , Abidogun Tolulope M. , Felton Julia W. , Magidson Jessica F. 
Published: December 2022

Abstract
Background: The peer recovery specialist (PRS) workforce has rapidly expanded to increase access to substance use disorder services for underserved communities. PRSs are not typically trained in evidence-based interventions (EBIs) outside of motivational interviewing, though evidence demonstrates the feasibility of PRS delivery of certain EBIs, such as a brief behavioral intervention, behavioral activation (BA). However, characteristics that predict PRS competency in delivering EBIs such as BA remain unknown, and are critical for PRS selection, training and supervision if the PRS role is expanded. This study aimed to explore the outcomes of a brief PRS training in BA and identify predictors of competence.
Method: Twenty PRSs completed a two-hour training on PRS-delivered BA. Participants completed baseline and post-training assessments, including role plays and assessments of PRS characteristics, attitudes towards EBIs, and theoretically-relevant personality constructs. Role plays were coded for competence (BA specific and PRS skills more broadly, ie., PRS competence) and changes were assessed from baseline to post-training. Linear regression models tested factors predicting post-training competence, controlling for baseline competence.
Results: There was a significant pre-post change in BA competence (t = -7.02, p= <0.001) such that post-training competency was higher. Years working as a PRS significantly predicted post-training BA skills (B=.16, p=.005). No variables predicted post-training PRS competence.
Conclusions: This study provides preliminary evidence that BA may be appropriate for dissemination to PRSs through brief trainings, particularly for PRSs with more work experience. However, additional research is needed to examine predictors of competence among PRSs.
Immunosuppressed children and young people, psychosocial wellbeing, and the COVID-19 pandemic
Authors: Driessens Corine , Mills Lynne , Patel Ravin , Culliford David , Gbesemete Diane , Lee Emma , Shaunak Meera , Chappell Harry , Faust Saul N. , Graaf Hans 
Published: December 2022

Abstract
Purpose: Early on in the COVID-19 pandemic, research highlighted the impact of the pandemic on the psychosocial wellbeing of children and young people (CYP). The long-term consequences of the pandemic on clinically vulnerable CYP is however unclear. This study aims to describe the psychosocial experiences of immunosuppressed CYP while Britain moved from the COVID-19 pandemic to epidemic.
Methods: We invited 1021 CYP participating in the ImmunoCOVID-19 study to complete a mental wellbeing survey in November/December 2021, January/February 2022, and March/April 2022, 467 accepted the invitation. At these 3 timepoints we assessed health-related quality of life (HRQOL) using the Kidscreen-27 and mood using the positive and negative affect scale. A linear mixed model repeated measure approach was used to analyse this prospective cohort data.
Results: At the first 2 timepoints, the COVID-19 pandemic timepoints, the CYP reported HRQOL levels that were noticeably lower compared to pre-COVID-19 norm levels. However, as the immunosuppressed CYP moved towards the COVID-19 epidemic, HRQOL levels significantly increased and negative mood decreased, indicating that these CYP were recovering from the impact the COVID-19 pandemic had on their psychosocial wellbeing. Our findings confirmed early pandemic findings indicating that younger children were less affected by the COVID-19 pandemic and that individuals living in low-income households were more affected by the pandemic. Moreover, parental anxiety and/or depression decreased CYP’s psychosocial wellbeing.
Conclusion: Health care provided to immunosuppressed CYP should include family guidance and interventions to support not only the psychosocial wellbeing of the paediatric patients but also other family members.
Diurnal variations in light intensity and different temperatures play an important role in controlling cyanobacterial blooms
Authors: Rahman Mizanur , Asaeda Takashi , Abeynayaka Helayaye Damitha Lakmali 
Published: December 2022

Abstract
Temperature and light intensity have a significant impact on cyanobacteria. This study conducted laboratory experiments to evaluate the combined effect of different temperatures and diurnal light intensities on cyanobacteria. The sufficient Microcystis aeruginosa and Phormidium ambiguum cells were transferred into three incubators at 30°C, 20°C, and 10°C temperatures for 23 days to acclimatize. After 23 days of incubation, the light intensities were changed diurnally hourly by 100 µmol m-2 s-1 starting from 6:00 to 18:00, where maximum light intensity reached 600 µmol m-2 s-1 at 11:00 to 13:00 and then decreased parallel till 18:00. The samples were collected at three-hour intervals — 6:00, 9:00, 12:00, 15:00, 18:00, and 21:00 — to analyze hydrogen peroxide (H2O2) concentration, protein concentration, chlorophyll-a (Chl-a) content, and catalase (CAT) activity. M. aeruginosa and P. ambiguum showed an increasing trend of H2O2, Chl-a, and CAT for 30°C, 20°C, and 10°C until 15:00, and after that, it decreased with decreasing PAR variations. There was a significant positive effect of temperature in M. aeruginosa and P. ambiguum on H2O2 concentration (30°C to 10°C, p< 0.001 and p<0.01 respectively), protein concentration (30°C to 10°C, p< 0.001 in both species), and Chl-a content (30°C to 10°C, p< 0.001 in both species). CAT activity was directly proportional to H2O2 concentration at each temperature. Chl-a/protein content in lowering temperatures (30°C to 10°C) harms both species' growth conditions. These findings would provide the necessary tools for treating cyanobacterial blooms.
An A-typical Anatomical Variation of the Petrosphenoidal Ligament in a Newborn Cadaver
Authors: KARAPINAR Burak Oğuzhan , WARILLE Aymen A. , BAŞ Orhan , EMİRZEOĞLU Mehmet , BİLGİÇ Sait 
Published: December 2022

Abstract
Purpose:To report an atypical anatomical variation of the petrosphenoidal ligament in a newborn cadaver and to discuss its clinical significance.
Methods: During a study of 10 newborn cadavers, the skull base was dissected to reveal the anatomy of the petrosphenoidal ligament and its relationship with the abducens nerve. An atypical anatomical variation was observed, and this is described. The length of the right and left ligaments to the point where it splits into two arms, the joint length of the two ligaments at the junction of the clivus, the length of the ligament proceeding to the posterior clinoid process, and the abducens nerve’s diameter as it passes below the ligament were measured on ImageJ software.
Results: The petrosphenoidal ligaments were y-shaped, and the attachment of the proximal ligaments was bifid. In the midline above the clivus, some ligament bundles joined the contralateral petrosphenoidal ligament, whilst another group of bundles originated at the posterior clinoid process. At the entry to Dorello's canal, the abducens nerve had a diameter of 0.59 mm on the left and 0.65 mm on the right. The part of the ligaments converging on the clivus in the midline after dividing into two arms was 10.68 mm.
Conclusions: We think that this case report will provide useful information for surgical procedures to the petroclival region, transnasal surgical anpproaches, and surgical interventions involving the carotid artery.
The Bared External Anal Sphincter (BEAS), a New Technique for High Horseshoe Anal Fistula: a Hospital-based Cohort Study
Authors: Du Peixin , Wang Zhenyi , Wang Qingming , Mei Zubing 
Published: December 2022

Abstract
Background
The aim of this study was to introduce a new technique, the bared external anal sphincter technique, and to evaluate its effectiveness and safety for primary or recurrent high horseshoe anal fistula (HHAF).
Methods
We used data from a tertiary referral hospital’s prospective database of a hospital-based cohort. All the patients underwent the bared external anal sphincter procedure. The main outcomes were the 6-month cure rate, Visual Analog Scale pain score (VAS-PS) and Cleveland Clinic Florida incontinence score (CCF-IS). The secondary outcomes included the Quality of Life in Patients with Anal Fistula Questionnaire score (QoLAF-QS), Bristol stool chart and postoperative complications.
Results
A total of 48 HHAF patients (39 males) with a mean age of 34.20 years (SD 9.04; range, 21-54) were analyzed in this prospective study. At the 6-month follow-up, the average VAS-PS and CCF-IS were 0.81 (SD 2.28; range, 0-10) and 1.29 (SD 2.87; range, 0-13), respectively. Three patients (6.25%) experienced recurrent symptoms but recovered after surgical management. Urinary retention occurred in 1 case (2.78%). No other postoperative complications were reported. No patient had anal incontinence.
Conclusion
The bared external anal sphincter procedure is a safe, effective and sphinctersparing modality for patients with primary or recurrent HHAF.
Ethics and dissemination
Ethical approval was obtained from the ethics committee of Shuguang Hospital Affiliated with Shanghai University of Traditional Chinese Medicine (Approval No. 2020-823-30-01). Written informed consent was obtained from each participant.
Molecular mechanism of phosphopeptide neoantigen immunogenicity
Authors: Patskovsky Yury , Natarajan Aswin , Patskovska Larysa , Nyovanie Samantha , Joshi Bishnu , Morin Benjamin , Brittsan Christine , Huber Olivia , Gordon Samuel , Michelet Xavier , Schmitzberger Florian , Stein Robert B. , Findeis Mark A. , Hurwitz Andy , Dijk Marc Van , Buell Jennifer S. , Underwood Dennis , Krogsgaard Michelle 
Published: December 2022

AbstractAltered protein phosphorylation in cancer cells often leads to surface presentation of phosphopeptide neoantigens. However, their role in cancer immunogenicity remains unclear. Here we describe a mechanism by which an HLA-B*0702-specific acute myeloid leukemia phosphoneoantigen pMLL747-755(EPR(pS)PSHSM) is recognized by cognate TCR27, which is a candidate for immunotherapy of AML. We show that the replacement of phosphoserine P4with serine or phosphomimetics does not affect the pMHC conformation or peptide-MHC affinity but abrogates the TCR27-dependent T cell activation and weakens binding between TCR27 and pMHC. We determined the crystal structures for TCR27 and cognate pMHC, mapped the pMHC-TCR interface by TROSY-NMR, generated a ternary pMHC-TCR complex using information-driven protein docking, and identified key polar interactions between phosphate group at P4and TCR27 that are crucial for ternary complex stability and TCR27 specificity. These data will support development of cancer immunotherapy through target expansion and TCR optimization. *The authors would like to note that Yury Patskovsky and Aswin Natarajan contributed equally.
Abundance of Ruminococcaceae is Associated with Claudin 22 Gene Expression and Body Weight in Mice
Authors: Nemoto Shino , Kubota Tetsuya , Ohno Hiroshi 
Published: December 2022

Abstract
We aimed to identify gut microbiota that influences body weight by elucidating the association with diets and host genes. Germ-free (GF) mice with and without fecal microbiota transplant (FMT) were fed a normal, high-carbohydrate, or high-fat diet. FMT mice exhibited greater total body weight, adipose tissue and liver weights, blood glucose, insulin, and total cholesterol levels, and oil droplet size than the GF mice, regardless of diet. However, the extent of weight gain and metabolic parameter levels associated with gut microbiota depended on the nutrients ingested. For example, a disaccharide- or polysaccharide-rich diet caused more weight gain than a monosaccharide-rich diet. An unsaturated fatty acid-rich diet had a greater effect on increased insulin by microorganisms than a saturated fatty acid-rich diet. Perhaps the difference in microbial metabolites produced from substances taken up by the host created metabolic differences. Therefore, we analyzed such dietary influences on gut microbiota, differentially expressed genes between GF and FMT mice, and metabolic factors including body weight. The results revealed a correlation between increased weight gain, a fat-rich diet, increased Ruminococcaceae abundance, and decreased claudin 22 gene expression. Thus, prevention of claudin 22 downregulation by manipulating Ruminococcaceae metabolism may inhibit weight gain.
Physiological Parameters Response to Hydraulic Resistance Training of College Students: a Study of Women Health
Authors: Karthikeyan K.Manosakthi , K.Divya  
Published: December 2022

Abstract
Objective

Whom sports for health aims to ensure a healthy and safe event for women. The study aims to determine college women students' physiological responses to hydraulic resistance training. Although this hydraulic resistance training effect can reflect the resting pulse rate, systolic pressure and diastolic pressure, resistance exercise may be safer for all populations, especially for untrained women.

Methods

They were randomly divided and assigned into two groups of fifteen each as the experimental group (HRTG) 1(n = 15) and control group 1 (n = 15). The data were collected before and after the training of 8 weeks, paired sample t-test was used to find the significant difference between the groups.

Results

The Statistical analysis of the HRTG, the control group of paired sample t-test. The obtained t-test of significant improvement in resting pulse rate is 41.01, systolic pressure is 40.44, and diastolic pressure is 31.59 of post-test was more significant than the table value of the degree of freedom 2.76 (14) required for the significance at 0.05 level. The hydraulic resistance training group responded to the training with a more positive influence on physiological variables, when compared hydraulic resistance training group better than the CG.

Conclusion

It concluded that the study significantly improved the hydraulic resistance training and improved their resting pulse rate, systolic pressure and diastolic pressure and enhanced their daily activity level of fitness and improved lifestyle.
Does Professional Development Effectively Support the Implementation of Inclusive Education? A Systematic Review and Meta-Analysis
Authors: Donath Johanna L. , Lüke Timo , Graf Elisabeth , Tran Ulrich , Götz Thomas 
Published: December 2022

Abstract
Inclusive education is a reform aimed at educating all students in general classrooms, independent of diversity features such as special educational needs, giftedness, or migration. Its successful implementation requires teachers with professional knowledge about inclusive education, skills to address the diverse needs in the classroom, and positive beliefs toward inclusive education. Teachers are provided with professional development opportunities, but are these effective in improving their learning process and positively impacting students’ behavior and achievement? We conducted a systematic review and meta-analysis to address this question. The screening of 12,050 search results revealed 342 eligible studies with more than 155,000 participants and 1,123 effects from four outcome categories: teachers’ knowledge, skills, and beliefs and students’ behavior and achievement. We observed positive, though varying, effects on all four outcome categories: large effects on knowledge regarding inclusive education (g = 0.93), moderate effects on teachers’ skills (g = 0.49), small effects on teachers’ beliefs (g = 0.23) and small-to-moderate effects on student behavior (g = 0.37). We also examined factors that might explain the differences in the strength of training effects. The data suggest that long-term training with high practical relevance and active learning opportunities facilitates transfer to schools.
Ökopassionen
Authors: Lötscher Christine 
Published: December 2022

[English title and abstract below]
Die environmental humanities florieren auch im deutschsprachigen Raum, und Konzepte der neomaterialistischen Theorie finden mehr und mehr Eingang in populäre Narrative rund um Klimawandel und Ökologie. Das zeigt sich in Genres wie Nature Writing und Climate Fiction, die mit Metaphern von Verwobenheit (entanglement) operieren, ebenso wie in den zahllosen Kinder- und Jugendbüchern, die ökologische Themen aufgreifen und Geschichten erzählen, in denen es um eine besondere Affinität zwischen Kindern und nichtmenschlichen Wesen geht. Dabei stehen oft die Emotionen der kindlichen und jugendlichen Figuren im Zentrum, ihre Angst, Sorge, Empörung und Wut angesichts des Schwindens der Artenvielfalt. Diese Emotionen, wie ich in diesem Beitrag zeigen möchte, bieten für Kinder- und Jugendmedien Zugang zu einer Vielfalt von Erzählungen rund um das Zusammenleben von Menschen und nichtmenschlichen Wesen, rund um die Bedeutung, die den vielfältigen Erfahrungen mit Tieren, Pflanzen und Landschaften zugeschrieben wird. So entsteht aus der Tradition des Erzählens aus der Perspektive von Kindern und Jugendlichen ein neuer Blick auf eine vielfach verwobene Welt – mitunter begleitet von einer kritischen Auseinandersetzung mit popularisierten neomaterialistischen Topoi. Kindliche und jugendliche Protagonist:innen werden mit ihren Ökopassionen zu Reflexionsfiguren im Verhältnis von Mensch, Natur und Medien.

EcopassionsTowards a New Materialist Reading of Children’s and Young Adult Media in the Anthropocene
Environmental humanities are flourishing in the German-speaking world, and concepts of new materialist theory are increasingly finding their way into popular narratives about climate change and ecology. This is evident in genres such as nature writing and climate fiction that operate with metaphors of entanglement, but also in the countless books for children and young adults books that take up ecological themes and tell stories about special affinities between children and non-human beings. These often focus on the emotions of the child and adolescent characters, on their fear, concern, outrage and anger in the face of disappearing biodiversity. These emotions, as I will show in this article, allow children's and youth media to access a variety of narratives about the coexistence of human and nonhuman beings, and about the meaning ascribed to the wide range of experience with animals, plants, and landscapes. A new perspective on a multiply interwoven world thus emerges from the tradition of storytelling from the point of view of children and young people, sometimes accompanied by a critical examination of popularised new materialist topoi. With their ecopassions, young protagonists become tropes of reflection in the relationship between humans, nature and media.
Was kannst du tun?
Authors: Ritter Alexandra , Ritter Michael 
Published: December 2022

[English title and abstract below]
Gerade das Sachbilderbuch widmet sich in den letzten Jahren mit innovativen Darstellungs- und Erzählkonzepten verstärkt den Themen Klimawandel und Umweltschutz. Dem Medium wird dabei ein hohes Wirkungspotenzial hinsichtlich der Einstellungsänderung und Handlungswirksamkeit bei jungen Leser:innen zugeschrieben. Wie werden in diesem Kontext aber Klimawandel und Umweltschutz dargestellt? Wie informieren Sachbilderbücher und wie erzeugen sie Anschaulichkeit, Dichte und Verbindlichkeit? Solchen Fragen und den damit adressierten literarischen Phänomenen wendet sich der folgende Beitrag unter Rückgriff auf den Ecocriticism zu. Besonders in den Blick gerät dabei die lerntheoretische Konstruktion der Adressat:innen, die sich aus der impliziten Didaktisierung des Themas in der Buchgestaltung rekonstruieren lässt. Den Ausgangspunkt der Untersuchung bildet eine deskriptive Fragestellung: Wie wird mit der Problematik und Multierspektivität dieses komplexen Gegenstands (Klimawandel/Umweltschutz) umgegangen und wie wird der Gegenstand im Buch konstruiert und inszeniert? Die Befunde werden dann, normativ gewendet, vor dem Hintergrund der genrespezifischen Entwicklungen der Bilderbuchliteratur diskutiert.

What Can You Do?Climate and Environmental Protection in Information Picturebooks
In recent years, information picturebooks have turned increasingly, and with innovative presentational and narrative concepts, to the topics of climate change and environmental protection. It is assumed that these books have significant potential for changing attitudes and motivating action among young readers. But how are climate change and environmental protection presented in them? How do they create graphic clarity, density and commitment? This article addresses these questions in the context of ecocriticism studies while examining two contemporary information picturebooks. We ask how these issues are presented and staged in multimodal texts. We focus on the literary construction of the addressees from a pedagogical perspective, which can be reconstructed from the implied didacticism in the design of the picturebooks. The findings are discussed in terms of how the books can encourage and increase engagement with climate change and environmental protection.