bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of Production System of Shale Oil Development in Ordos basin, China
Authors: WAN Xiaolong , MA Shuwei , Fan Jianming , Zhang Yuanli , Zhang Chao 
Published: September 2022

Abstract
In this paper, production system(PS) of shale oil is optimized according to production data and indoor experiments, including core and fluid tests. Results showed that: ① Pressure drop rate at wellhead is a reasonable reference for the determination of post-fracture shut-in duration (PFSID). When pressure at a wellhead of horizontal well is relatively stable and the pressure drop less than 0.1mpa per day for three consecutive days, PFSID ends; ② Flowback intensity of fracturing fluid affects the effectiveness of proppant underground, thus flowback intensity can be determined by the critical flow rate and safety factor of each proppant; ③ Flowback intensity should be varied during different development stages, which could be divided into four according to production gas and oil ratio(GOR) of a shale oil horizontal well: low, medium-high, high and high-low production GOR. During the stage of low production GOR, ratio of flow pressure and saturation pressure should be maintained greater than 1.0, and the initial daily liquid productivity for a hundred-meter oil-bearing lateral length in a horizontal well is 2.0-2.5m3/d; and during the medium -high production GOR, high production GOR and high-low production GOR stages, the responding initial daily liquid productivity should be maintained between 0.8-1.0 or less than 0.8 respectively.
High Temperature Failure and Microstructural Investigation of Additive Manufactured Rene 41
Authors: James William Sean , Ganguly Supriyo , Pardal Goncalo 
Published: September 2022

Abstract
In developing a wire-arc direct energy deposition process for creep resistant alloys used in high-speed flight applications, structures were built from nickel-based superalloy Rene 41. Samples of AM material were analysed for their microstructural and mechanical properties, in both as deposited (AD) and heat-treated (HT) conditions. Tensile specimens were tested at room-temperature, 538, 760, and 1000 °C. Macroscopically, large columnar grains made up of a typical dendritic structure were observed. Microscopically, significant segregation of heavier elements, grain boundary precipitates, and secondary phases were observed, with key differences observed in HT material. There was a clear distinction between failure modes at different testing temperatures and between AD and HT variants. A fractographic investigation found a progressive move from brittle to ductile fracture with increasing testing temperature in both AD and HT conditions, as well as microstructural features which support this observation.
Path planning and pose correction of robot laser cleaning process for specific surfaces of parts
Authors: Pan Zhigui , Liu DeFu , Li Shudan , Deng Zixin , Liu Jian , Chen Tao 
Published: September 2022

Abstract
The purpose of this paper is to solve a series of problems, such as the difficulty in accurately controlling the specific surfaces, and the interference between the laser beam and the parts, when the laser is used to clean mechanical parts with complex surfaces by using robots. Firstly, a region segmentation algorithm of the stereo lithography (STL) model was designed, and the feature surfaces of the model were obtained by using the dihedral angle as the criterion. Then the path points which could easily cause interference between the laser beam and the part to be cleaned were detected by the method of ray intersection, and the pose of the robot was modified according to the normal vector of two non-interference points that were adjacent to the continuous interference points respectively. Finally, the proposed method was validated by scanning path visualization and robot laser cleaning process experiments. The results showed that the robot can successfully clean the specific surface of the test workpiece without interference by following the laser cleaning path generated by the proposed algorithm, and the transition of the robot pose is smooth, which proves the effectiveness of this study. The method is also useful for the path planning of robots in other processing fields.
Observation and simulation investigation for the crater formation under discharge plasma movement in RT-WEDM
Authors: Xi Xue-Cheng , Li Zi-Lun , Gao Qiang , Zhang Ya-Ou , Zhao Wan-Sheng 
Published: September 2022

Abstract
Observations of the discharge gap were conducted to investigate the discharge plasma motion in reciprocated traveling wire electrical discharge machining (RT-WEDM). It was found that the discharge plasma continuously slides on the surface of a workpiece. An oscillating moving heat source is proposed to better conform the characteristics of the discharge plasma motion. Based on the oscillating moving heat source, a novel thermal-fluid coupling model by adopting a level-set method was proposed to investigate the formation of a crater and the effects of machining parameters on the crater. Discharge plasma sliding, latent heat, and molten pool forces are comprehensively considered in the proposed model. Simulation and experimental results show that the sliding discharge plasma has a significant effect on a crater. At the end of a discharge, a considerable proportion of molten material remains in the molten pool. A high sliding speed of discharge plasma can lead to a low aspect ratio in a crater and a thin recast layer. Besides, due to the discharge plasma sliding, an increase in pulse duration can significantly increase the length of the crater and decrease the aspect ratio, while an increase in peak current can significantly increase the depth and volume of a crater. Simulation and experimental results also show that the morphologies of the simulated crater and experimental crater are consistent, verifying the feasibility and accuracy of the proposed simulation model in explaining the mechanisms of crater formation in RT-WEDM.
Relationship between spatial topology and loess permeability based on computed tomography–scanning technology
Authors: Yang Guohui , Li Chi , Shang Yan , Gao Yu , Li Shuanhu 
Published: September 2022

Abstract
Loess’s permeability properties increase under alternating wet and dry conditions, a phenomenon that is closely related to the soil’s pore structure. Among the pore structure properties, spatial topology is important. To further investigate the relationship between loess’s spatial topography and its infiltration properties under alternating wet and dry conditions, loess with different water contents is scanned by an industrial computed tomography (CT) scanner, and single-phase seepage simulations are performed. The results show that the diameters of the connected pore spaces increase along with water content; the pore throat length is positively correlated with the water content, reaching a maximum of 753.32 μm; and greater water contents result in stronger pore connectivity and larger increases of connected pore space coordination numbers. The results of the permeability simulation show that increases in connected pores, pore throat lengths, and coordination numbers lead to increased permeability, and the correlation is strongest between the coordination number and permeability. It is important to study the relationship between spatial topology and loess permeability for practical engineering applications.
Calmodulin Modulation of Insect Ryanodine Receptor
Authors: Lin Lianyun , Jiang Heng , Hadiatullah Hadiatullah , Korza Henryk , Gu Yucheng , Yuchi Zhiguang 
Published: September 2022

Abstract
Ryanodine receptor (RyR) is a giant calcium release channel located on the membrane of the endoplasmic reticulum (ER). As a key protein in the calcium signaling pathway, RyR function is modulated by a number of protein and small molecule modulators. Although RyR has been identified as an important insecticide target, the regulation of insect RyR by some of these modulators is still largely unknown. Here, we report the regulation of RyRs from two major agricultural pests, diamondback moth and fall armyworm, by insect calmodulin (CaM). The recombinantly expressed full-length insect RyR could be pulled down by insect CaM in the presence of Ca2+, but the efficiency is lower compared to rabbit RyR1 and insect RyR with the CaM-binding domain (CaMBD) replaced by a mammalian RyR sequence. Interestingly, the enhanced binding of CaM in the mutant insect RyR resulted in increased sensitivity to the diamide insecticide chlorantraniliprole (CHL), suggesting that this CaM-CaMBD interface could be targeted by potential synergists. The thermodynamics of the binding between insect CaM and CaMBD was characterized by ITC and the key residues responsible for the insect-specific regulation were identified through mutagenesis studies. Finally, a homology model was created to predict the CaM-binding mode in insect RyR, which can be used to guide the structure-based design of future pesticides.
Performance Evaluation of Reinforced Concrete Building
Authors: Amatya Nikshan 
Published: September 2022

Abstract
High rise buildings are increasing rapidly in all over the world. The overall performance of building must be evaluated to ensure the safety of all the structural component of a building against multiple hazards. A 36-story building with 3-story basement was selected to study the effect of seismic and wind load on the performance of reinforced concrete building. Three different analyses; linear static analysis for gravity and wind load, response spectrum analysis for design-basis earthquake (DBE) using code-based design and nonlinear time-history analysis (NLTHA) for maximum considered earthquake (MCE) using performance-based design was conducted. The elastic model was created in ETABS for linear static wind analysis and traditional code-based response spectrum analysis at DBE level. The inelastic model was created in Perform 3-D for performance-based analysis at MCE level. The result obtained from analyses were evaluated using these three analyses and the overall performance of building was compared. The study demonstrated that the demands obtained from the MCE level using performance-based design were higher and it must be considered for the design of high-rise building to ensure the overall serviceability and safety.
Characterization of Lantana camara roots (Pentacyclic Triterpenoid)and Mutagenicity Testing of extracted Oleanolic acid Using Salmonella typhimurium.
Authors: Gupta Navika Gupta Navika , Chandra Saurabh Chandra Saurabh , Singh Anu T.Singh Anu T , Jaggi Manu jaggi Manu 
Published: September 2022

Abstract
Objective
The objective of the present study was to isolate oleanolic acid from the roots of Lantana camara, and characterize it chemically using DSC, HPLC, and FTIR methods, and additionally carrying out a short term assay for assessment of its mutagenic potential by conducting bacterial reverse mutation test to evaluate the ability of the “Oleanolic acid (Pentacyclic Triterpenoid)” to induce point mutations in tester strains of Salmonella typhimurium in both presence and absence of exogenous metabolic activation system (S9) containing microsomal enzymes.
Methods
Differential scanning calorimetry (DSC), High Performance Liquid chromatography (HPLC), and Fourier transform infrared (FTIR) spectrometers were used to chemically analyze the isolated molecule. Oleanolic acid was utilized to carry out Preliminary Cytotoxicity and mutagenicity study.
Results
According to the results of spectrophotometric research, oleanolic acid extracted from Lantana camara roots exhibits identical spectrum characteristics to standard oleanolic acid also the mutagenic potential of Oleanolic acid (Pentacyclic Triterpenoid). Oleanolic acid was found to be non-mutagenic in all five test strains of Salmonella typhimurium—TA98, TA100, TA102, TA1535, and TA1537 employing plate incorporation assays
Conclusion
It may be determined that oleanolic acid isolated from Lantana camara roots gives identical, identifiable signals and absorbance like previously reported reference standard based on the results of DLC, HPLC, and FTIR spectra and their interpretation and was determined that oleanolic acid purified from Lantana camara roots is non-mutagenic in Salmonella typhimurium.
Mechanical thrombectomy combined with Intravenous thrombolysis for acute ischemic stroke: A systematic review and meta-analyses
Authors: Zheng Meiling , Li Li , Chen Lizhou , Li Bin , Feng Cuiling 
Published: September 2022

Abstract
Purpose
To assess the clinical value of mechanical thrombectomy (MT) combined with intravenous thrombolysis (IVT) in acute ischemic stroke (AIS) by comparing it with the direct MT (dMT).
Method
We conducted a systematic review and meta-analysis involving studies from four databases including PubMed, Embase, WOS, and Cochrane Library. We collected observational studies and randomized controlled studies (RCTs) published from January 2011 to June 2022, providing data about outcomes in terms of functional independence (FI), excellent outcomes (mRS score:0–1), successful recanalization (SR), symptomatic intracerebral hemorrhage (sICH), any intracerebral hemorrhage (aICH), and mortality at three-month or discharge.
Results
A total of 55 eligible studies (nine RCTs and 46 observational studies) were included. For RCTs, the MT + IVT group was superior in FI (OR:1.27, 95%CI:1.11–1.46), excellent outcomes (OR:1.21, 95%CI:1.03–1.43), SR (OR:1.23, 95%CI:1.05–1.45), mortality (OR:0.72, 95%CI: 0.54–0.97) in crude analyses. In adjusted analyses, the MT + IVT group reduced the risk of mortality (OR:0.65, 95%CI: 0.49–0.88). For observational studies, the results of FI (OR:1.34, 95%CI:1.16–1.33), excellent outcomes (OR:1.30, 95%CI:1.09–1.54), SR (OR:1.23, 95%CI:1.05–1.44), mortality (OR:0.70, 95%CI:0.64–0.77) in the MT + IVT group were better. Additionally, the MT + IVT group increased the risk of hemorrhagic transformation (HT) including sICH (OR:1.16, 95%CI:1.11–1.21) and aICH (OR:1.24, 95%CI:1.05–1.46) in crude analyses. In crude analyses, significant better outcomes were seen in the MT + IVT group on FI (OR:1.36, 95%CI:1.21–1.52), excellent outcomes (OR:1.49, 95%CI:1.26–1.75), and mortality (OR:0.73, 95%CI: 0.56–0.94).
Conclusions
The MT + IVT therapy did improve the prognosis for AIS patients and did not increase the risk of HT compared with dMT therapy.
Risk factors and prognosis of early neurological deterioration in patients with posterior circulation cerebral infarction
Authors: Li Hui , Zheng Yi , Zhang Ding-Ding , Cui Xiu-Ying , Zhao Xin , Zhang Guan-Wen , Yang Fei , Yu Fu , Fan Xiao-Tian , Jiang Hao , Shi Jian-Ming , Wang Bo , Zhang Jiang-Tao , Zhang Ran 
Published: September 2022

Abstract
Background: The incidence, risk factors, and pathogenesis of early neurological deterioration (END) in posterior circulation stroke are still unclear. In this study, we aimed to determine the risk factors and prognosis of END in patients with acute posterior circulation cerebral infarction.
Methods: Acute posterior circulation ischemic stroke patients who had completed neuroimaging within 72 hours of onset were selected from a prospective registry study.
Demographic characteristics, physiological data, medical history, laboratory data, in-hospital evaluation, neurological severity and TOAST classification, treatment, and the modified Rankin Scale (mRS) score of patients were assessed. Early neurological deterioration was defined as an increase of ≥2 points in the National Institutes of Health Stroke Scale score between the baseline and 72-hour evaluation. Favorable and poor outcomes were defined as mRSs of 0–2 and ≥3, respectively, at 3 months. The incidence and risk factors were evaluated by univariate and multivariate regression analysis (step-back method).
Results: The analysis included 455 subjects with an acute posterior circulation non-cardiac ischemic stroke, 330 (72.53%) of them male, with an average age of 63.12 (±10.14) years and with 47 (10.33%) having END. The results of univariate and multivariate logistic regression analysis showed that BATMAN scores ≥5 (OR: 0.1, 95% CI: 0.02–0.53, P < 0.01), large artery atherosclerosis (OR: 11.55, 95% CI: 4.18–31.93, P < 0.01), vascular stenosis >50% (OR: 2.44, 95% CI: 1.1–5.42, P = 0.029), reperfusion therapy (OR: 4.21, 95% CI: 1.66–10.64, P < 0.01), and the distribution of pontine lesions (OR: 5.66, 95% CI: 2.39–13.44, P< 0.01) were significantly associated with END. Patients with END had a lower rate of favorable outcomes at discharge and long-term follow-up (P < 0.001), regardless of whether they received reperfusion therapy.
Conclusion: The lesion distribution of the pons, the progression of temporo-occipital lobe lesions, and large arterial atherosclerosis are independent risk factors of END that might predict a poor short- and long-term prognosis.
Switchable moiré potentials in ferroelectric WTe2/WSe2 superlattices
Authors: Kang Kaifei , Zhao Wenjin , Zeng Yihang , Watanabe Kenji , Taniguchi Takashi , Shan Jie , Mak Kin Fai 
Published: September 2022

Abstract
Moiré materials, with superlattice periodicity many times the atomic length scale, have enabled the studies of strong electronic correlations and band topology with unprecedented tunability. However, nonvolatile control of the moiré potentials, which could allow on-demand switching of the superlattice effects, has not been achieved to date. Here we demonstrate the switching of the correlated and moiré band insulating states and the associated nonlinear anomalous Hall effect by the ferroelectric effect. This is achieved in a ferroelectric WTe2 bilayer of the Td structure with a centered-rectangular moiré superlattice induced by interfacing with a WSe2 monolayer of the H structure. The results can be understood in terms of polarization-dependent charge transfer between two WTe2 monolayers, which possess very different moiré potential depths; ferroelectric switching thus turns on/off the superlattice. Our study demonstrates the potential of creating new functional moiré materials by incorporating intrinsic symmetry-breaking orders.
Clinical Characteristics of Rheumatoid Arthritis Patients with Interstitial Lung Disease: Baseline Data of a Single-Centre Prospective Cohort
Authors: Kim Hyoungyoung , Cho Soo-Kyung , Song Yeo-Jin , Kang Juyeon , Jeong Seung-A , Kim Hye Won , Choi Chan-Bum , Kim Tae-Hwan , Jun Jae-Bum , Bae Sang-Cheol , Yoo Dae-Hyun , Lee Hyun , Park Dong Won , Sohn Jang Won , Yoon Ho Joo , Hong Su Jin , Yoo Seung-Jin , Choi Yo Won , Lee Youkyung , Kim Sang Heon , Sung Yoon-Kyoung 
Published: September 2022

Abstract
Objectives: To establish a prospective cohort for rheumatoid arthritis (RA) patients with interstitial lung disease (ILD) and to identify their clinical features compared to those without ILD.
Methods: With a multidisciplinary collaborative approach, a single-centre cohort for RA patients with ILD (RA-ILD) was established in May 2017, and enrolment data from May 2017 to March 2021 was used to compare the clinical features of RA patients without ILD (RA-non ILD). Multivariable logistic regression analysis was used to identify factors associated with ILD in RA patients.
Results: Among 148 RA-ILD patients and 410 RA-non ILD patients, the RA-ILD group were older (65.8 ± 9.9 vs. 58.0 ± 10.4 years, P < 0.001) and included more males (35.8% vs. 14.6%, P < 0.001) than the RA-non ILD group. The RA-ILD group had a higher proportion of late-onset RA patients (age ≥ 60 years) than in comparators (43.9% vs. 14.2%, P < 0.001). Multivariable logistic regression analysis showed that higher age at RA onset (OR 1.056, 95% CI 1.021-1.091), higher body mass index (BMI) (OR 1.65, 95% CI 1.036-2.629), smoking history (OR 2.484, 95% CI 1.071-5.764), and oral glucocorticoid use (OR 3.562, 95% CI 2.160-5.874) were associated with ILD in RA patients, whereas methotrexate use was less likely to coexist with ILD (OR 0.253, 95% CI 0.155-0.412).
Conclusions: Higher RA onset age, smoking history, and higher BMI were associated with presence of ILD among RA patients. Oral glucocorticoids were more frequently used whereas methotrexate was less likely to be used in RA-ILD patients.
An Effective Security Comparison Protocol in Cloud Computing
Authors: Chen Yuling , Tao Junhong , Li Tao , Cai Jiangyuan , Ren Xiaojun 
Published: September 2022

Abstract
Secure comparison protocol is an important branch of secure multi-party computation(SMPC), which compares the size of input data without disclosing any information between participants. The development of cloud computing provides an application platform for SMPC, but it also brings new challenges. In cloud computing with SMPC, clients need to process their own data and submit the processed data to a cloud server, which then performs the computation. In this process, not only the clients need to maintain an honest state at all times, but sensitive data on the cloud server side may also be exposed. In this paper, zero-knowledge proof and homomorphic encryption techniques are used to improve Damgård-Geisler-KrØigaard(DGK) comparison protocol. The improved secure comparison protocol can not only safely calculate private data, but also be applicable to malicious participant model. Finally, the security analysis shows that the proposed scheme not only ensures the privacy security of participants, but also ensures the data fairness of comparison protocols.
The ways our hearts tick together – A vegetative hyperscanning study involving a self-paced interpersonal motor entrainment task
Authors: Flory Stephan , Guglielmini Sabino , Scholkmann Felix , Marcar Valentine , Wolf Martin 
Published: September 2022

Abstract
Cardiac physiological synchrony between two persons is considered to be an important component of social interaction. Yet, the processes underlying physiological synchrony remain unclear. We aim to investigate these processes. 20 dyads (19 men, 21 women, age: mean 23.7, range: 18–35) engaged in a self-paced interpersonal tapping synchronization task under different conditions of blocking sensory communication channels. Applying wavelet transform coherence analysis, a significant increase in heart rate synchronization from baseline to task execution was found while there was no statistically significant difference across conditions. Furthermore, the control analysis, which assessed the synchrony between randomly combined dyads of participants showed no difference from the original dyads’ synchrony. We showed that interindividual cardiac physiological synchrony during self-paced synchronized finger tapping resulted from a task-related stimulus equally shared by all individuals. We hypothesize that by applying mental effort to the task, individuals changed into a similar mental state, altering their cardiac regulation. This so-called psychophysiological mode provoked more uniform, less variable oscillation patterns across all individuals leading to similar heart rate coherence independent of subsequent pairings. With this study, we provide new insights into heart rate coherence and highlight the importance of appropriate study design and control analysis.