bluuebunny/crossref_metadata_2025_split huggingface dataset:
Automated imaging-based abdominal organ segmentation and quality control in 20,000 participants of the UK Biobank and German National Cohort Studies
Authors: Kart Turkay , Fischer Marc , Winzeck Stefan , Glocker Ben , Bai Wenjia , Bülow Robin , Emmel Carina , Friedrich Lena , Kauczor Hans-Ulrich , Keil Thomas , Kröncke Thomas , Mayer Philipp , Niendorf Thoralf , Peters Annette , Pischon Tobias , Schaarschmidt Benedikt M. , Schmidt Börge , Schulze Matthias B. , Umutle Lale , Völzke Henry , Küstner Thomas , Bamberg Fabian , Schölkopf Bernhard , Rueckert Daniel , Gatidis Sergios 
Published: November 2022

AbstractLarge epidemiological studies such as the UK Biobank (UKBB) or German National Cohort (NAKO) provide unprecedented health-related data of the general population aiming to better understand determinants of health and disease. As part of these studies, Magnetic Resonance Imaging (MRI) is performed in a subset of participants allowing for phenotypical and functional characterization of different organ systems. Due to the large amount of imaging data, automated image analysis is required, which can be performed using deep learning methods, e. g. for automated organ segmentation. In this paper we describe a computational pipeline for automated segmentation of abdominal organs on MRI data from 20,000 participants of UKBB and NAKO and provide results of the quality control process. We found that approx. 90% of data sets showed no relevant segmentation errors while relevant errors occurred in a varying proportion of data sets depending on the organ of interest. Image-derived features based on automated organ segmentations showed relevant deviations of varying degree in the presence of segmentation errors. These results show that large-scale, deep learning-based abdominal organ segmentation on MRI data is feasible with overall high accuracy, but visual quality control remains an important step ensuring the validity of down-stream analyses in large epidemiological imaging studies.
Anisotropic magnetic property, magnetostriction, and giant magnetocaloric effect with plateau behavior in TbMn2Ge2 single crystal
Authors: Huang Shuai , Bai Yuming , Wan Kaiqi , Zhu Changming , Huo Dexuan , Tian Zhaoming 
Published: November 2022

AbstractThe ternary RMn2Ge2 (R = rare earth) intermetallic compounds have attracted great attention due to their interesting magnetic behaviors and magnetotransport responses. Here, we reported our observation of anisotropic magnetic property, magnetostriction, and magnetocaloric effect (MCE) in TbMn2Ge2 single crystal. Below the transition temperature of Tb magnetic sublattices ($$T_{{\text{C}}}^{{{\text{Tb}}}}$$

T

C

Tb

~ 95 K), strong Ising-like magnetocrystalline anisotropy is observed with an out-of-plane ferromagnetic moments 5.98 μB/f.u. along the easy c axis, which is two orders of magnitude larger than that of field along a axis. Above $$T_{{\text{C}}}^{{{\text{Tb}}}}$$

T

C

Tb

, a field-induced metamagnetic transition is observed from the spin-flip of Mn sublattices. During this transition, remarkable magnetostriction effect is observed, indicating of strong spin–lattice coupling. The responses of Tb and Mn sublattices to the magnetic field generate a giant magnetic entropy change ($$- \Delta S_{M}$$

-
Δ

S
M

) and large values of relative cooling power (RCP) and temperature-averaged entropy change (TEC). The calculated maximum magnetic entropy change ($$- \Delta S_{M}^{\max }$$

-
Δ

S

M

max

), RCP, and TEC(10) with magnetic field change of 7 T along c axis reach 24.02 J kg−1 K−1, 378.4 J kg−1, and 21.39 J kg−1 K−1 near $$T_{{\text{C}}}^{{{\text{Tb}}}}$$

T

C

Tb

, which is the largest among RMn2Ge2 families. More importantly, this giant MCE shows plateau behavior with wide window temperatures from 93 to 108 K, making it be an attractive candidate for magnetic refrigeration applications.
Abdominal aortic aneurysm monitoring via arterial waveform analysis: towards a convenient point-of-care device
Authors: Yavarimanesh Mohammad , Cheng Hao-Min , Chen Chen-Huan , Sung Shih-Hsien , Mahajan Aman , Chaer Rabih A. , Shroff Sanjeev G. , Hahn Jin-Oh , Mukkamala Ramakrishna 
Published: November 2022

AbstractAbdominal aortic aneurysms (AAAs) are lethal but treatable yet substantially under-diagnosed and under-monitored. Hence, new AAA monitoring devices that are convenient in use and cost are needed. Our hypothesis is that analysis of arterial waveforms, which could be obtained with such a device, can provide information about AAA size. We aim to initially test this hypothesis via tonometric waveforms. We study noninvasive carotid and femoral blood pressure (BP) waveforms and reference image-based maximal aortic diameter measurements from 50 AAA patients as well as the two noninvasive BP waveforms from these patients after endovascular repair (EVAR) and from 50 comparable control patients. We develop linear regression models for predicting the maximal aortic diameter from waveform or non-waveform features. We evaluate the models in out-of-training data in terms of predicting the maximal aortic diameter value and changes induced by EVAR. The best model includes the carotid area ratio (diastolic area divided by systolic area) and normalized carotid-femoral pulse transit time ((age·diastolic BP)/(height/PTT)) as input features with positive model coefficients. This model is explainable based on the early, negative wave reflection in AAA and the Moens-Korteweg equation for relating PTT to vessel diameter. The predicted maximal aortic diameters yield receiver operating characteristic area under the curves of 0.83 ± 0.04 in classifying AAA versus control patients and 0.72 ± 0.04 in classifying AAA patients before versus after EVAR. These results are significantly better than a baseline model excluding waveform features as input. Our findings could potentially translate to convenient devices that serve as an adjunct to imaging.
Reprogramming of pancreatic adenocarcinoma immunosurveillance by a microbial probiotic siderophore
Authors: Chaib Mehdi , Hafeez Bilal B. , Mandil Hassan , Daria Deidre , Pingili Ajeeth K. , Kumari Sonam , Sikander Mohammed , Kashyap Vivek K. , Chen Guo-Yun , Anning Emmanuel , Tripathi Manish K. , Khan Sheema , Behrman Stephen , Yallapu Murali M. , Jaggi Meena , Makowski Liza , Chauhan Subhash C. 
Published: November 2022

AbstractThere is increasing evidence suggesting the role of microbiome alterations in relation to pancreatic adenocarcinoma and tumor immune functionality. However, molecular mechanisms of the interplay between microbiome signatures and/or their metabolites in pancreatic tumor immunosurveillance are not well understood. We have identified that a probiotic strain (Lactobacillus casei) derived siderophore (ferrichrome) efficiently reprograms tumor-associated macrophages (TAMs) and increases CD8 + T cell infiltration into tumors that paralleled a marked reduction in tumor burden in a syngeneic mouse model of pancreatic cancer. Interestingly, this altered immune response improved anti-PD-L1 therapy that suggests promise of a novel combination (ferrichrome and immune checkpoint inhibitors) therapy for pancreatic cancer treatment. Mechanistically, ferrichrome induced TAMs polarization via activation of the TLR4 pathway that represses the expression of iron export protein ferroportin (FPN1) in macrophages. This study describes a novel probiotic based molecular mechanism that can effectively induce anti-tumor immunosurveillance and improve immune checkpoint inhibitors therapy response in pancreatic cancer.
Melanesia holds the world’s most diverse and intact insular amphibian fauna
Authors: Oliver Paul M. , Bower Deborah S. , McDonald Peter J. , Kraus Fred , Luedtke Jennifer , Neam Kelsey , Hobin Louise , Chauvenet Alienor L. M. , Allison Allen , Arida Evy , Clulow Simon , Günther Rainer , Nagombi Elizah , Tjaturadi Burhan , Travers Scott L. , Richards Stephen J. 
Published: November 2022

AbstractIdentifying hotspots of biological diversity is a key step in conservation prioritisation. Melanesia—centred on the vast island of New Guinea—is increasingly recognised for its exceptionally species-rich and endemic biota. Here we show that Melanesia has the world’s most diverse insular amphibian fauna, with over 7% of recognised global frog species in less than 0.7% of the world’s land area, and over 97% of species endemic. We further estimate that nearly 200 additional candidate species have been discovered but remain unnamed, pointing to a total fauna in excess of 700 species. Nearly 60% of the Melanesian frog fauna is in a lineage of direct-developing microhylids characterised by smaller distributions than co-occurring frog families, suggesting lineage-specific high beta diversity is a key driver of Melanesian anuran megadiversity. A comprehensive conservation status assessment further highlights geographic concentrations of recently described range-restricted threatened taxa that warrant urgent conservation actions. Nonetheless, by world standards, the Melanesian frog fauna is relatively intact, with 6% of assessed species listed as threatened and no documented extinctions; and thus it provides an unparalleled opportunity to understand and conserve a megadiverse and relatively intact insular biota.
Impact of physio-chemical spinning conditions on the mechanical properties of biomimetic spider silk fibers
Authors: Schmuck Benjamin , Greco Gabriele , Bäcklund Fredrik G. , Pugno Nicola M. , Johansson Jan , Rising Anna 
Published: November 2022

AbstractArtificial spider silk has emerged as a biobased fiber that could replace some petroleum-based materials that are on the market today. Recent progress made it possible to produce the recombinant spider silk protein NT2RepCT at levels that would make the commercialization of fibers spun from this protein economically feasible. However, for most applications, the mechanical properties of the artificial silk fibers need to be improved. This could potentially be achieved by redesigning the spidroin, and/or by changing spinning conditions. Here, we show that several spinning parameters have a significant impact on the fibers’ mechanical properties by tensile testing more than 1000 fibers produced under 92 different conditions. The most important factors that contribute to increasing the tensile strength are fast reeling speeds and/or employing post-spin stretching. Stretching in combination with optimized spinning conditions results in fibers with a strength of >250 MPa, which is the highest reported value for fibers spun using natively folded recombinant spidroins that polymerize in response to shear forces and lowered pH.
Chemical weathering over hundreds of millions of years of greenhouse conditions on Mars
Authors: Ye Binlong , Michalski Joseph R. 
Published: November 2022

AbstractChemical weathering profiles on Mars which consist of an upper Al clay-rich, Fe-poor layer and lower Fe/Mg clay-rich layer are believed to have formed due to precipitation-driven top down leaching process in an ancient, reducing greenhouse climate. Here we use remote sensing imagery and spectroscopy coupled with topographic data and crater chronology to explore the geological characteristics, stratigraphy and relative age of >200 weathering profiles across the southern highlands of Mars. We find that nearly all exposures show a similar, single stratigraphic relationship of Al/Si materials over Fe/Mg clays rather than multiple, interbedded mineralogical transitions. This suggests either one single climate warming event or, perhaps more likely, chemical resetting of weathering horizons during multiple events. While the time required to form a typical martian weathering profile may have been only ∼106−107years, the profiles occur in deposits dating from the Early Noachian into the Hesperian and suggest that chemical weathering may have occurred over a large range of geologic time, with a peak around 3.7–3.8 billion years ago.
Two-dimensional porous CeO2@Co3O4 sheet-like heterostructures for high-performance aqueous hybrid supercapacitors
Authors: Yang Guiyuan , Cheng Qihui , Liao Fangfang , Mao Lei , Zhao Xun , Chen Lingyun 
Published: November 2022

In this work, we have propose a simple and facile hydrothermal method for the synthesis of 2D porous CeO2@Co3O4 sheet-like heterostructures with superior supercapacitor performance.
One-to-One or One
Too Many
? Linking Sound-to-Letter Mappings to Speech Sound Perception and Production in Early Readers
Authors: Jevtović Mina , Stoehr Antje , Klimovich-Gray Anastasia , Antzaka Alexia , Martin Clara D. 
Published: November 2022

Purpose:
Effects related to literacy acquisition have been observed at different levels of speech processing. This study investigated the link between orthographic knowledge and children's perception and production of specific speech sounds.

Method:
Sixty Spanish-speaking second graders, differing in their phonological decoding skills, completed a speech perception and a production task. In the perception task, a behavioral adaptation of the oddball paradigm was used. Children had to detect orthographically consistent /t/, which has a unique orthographic representation (〈t〉), and inconsistent /k/, which maps onto three different graphemes (〈c〉, 〈qu〉, and 〈k〉), both appearing infrequently within a repetitive auditory sequence. In the production task, children produced these same sounds in meaningless syllables.

Results:
Perception results show that all children were faster at detecting consistent than inconsistent sounds regardless of their decoding skills. In the production task, however, the same facilitation for consistent sounds was linked to better decoding skills.

Conclusions:
These findings demonstrate differences in speech sound processing related to literacy acquisition. Literacy acquisition may therefore affect already-formed speech sound representations. Crucially, the strength of this link in production is modulated by individual decoding skills.
Vaginal Birth at Term – Part 1. Guideline of the DGGG, OEGGG and SGGG (S3-Level, AWMF Registry No. 015/083, December 2020)
Authors: Abou-Dakn Michael , Schäfers Rainhild , Peterwerth Nina , Asmushen Kirsten , Bässler-Weber Susanne , Boes Ulrike , Bosch Andrea , Ehm David , Fischer Thorsten , Greening Monika , Hartmann Katharina , Heller Günther , Kapp Claudia , von Kaisenberg Constantin , Kayer Beate , Kranke Peter , Lawrenz Burkhard , Louwen Frank , Loytved Christine , Lütje Wolf , Mattern Elke , Nielsen Renate , Reister Frank , Schlösser Rolf , Schwarz Christiane , Stephan Volker , Kalberer Barbara Stocker , Valet Axel , Wenk Manuel , Kehl Sven 
Published: November 2022

AbstractPurpose This guideline aims to summarize the current state of knowledge about vaginal birth at term. The guideline focuses on definitions of the physiological stages of labor as well as differentiating between various pathological developments and conditions. It also assesses the need for intervention and the options to avoid interventions. This first part presents recommendations and statements about patient information and counselling, general patient care, monitoring of patients, pain management and quality control measures for vaginal birth.Methods The German recommendations largely reproduce the recommendations of the National Institute for Health and Care Excellence (NICE) CG 190 guideline “Intrapartum care for healthy women and babies”. Other international guidelines were also consulted in specific cases when compiling this guideline. In addition, a systematic search and analysis of the literature was carried out using PICO questions, if this was considered necessary, and other systematic reviews and individual studies were taken into account. For easier comprehension, the assessment tools of the Scottish Intercollegiate Guidelines Network (SIGN) were used to evaluate the quality of the additionally consulted studies. Otherwise, the GRADE system was used for the NICE guideline and the evidence reports of the IQWiG were used to evaluate the quality of the evidence.Recommendations Recommendations and statements were formulated based on identified evidence and/or a structured consensus.
The Evolution of Pelvic Pouch Surgery: Optimal Pouch Design for an Ileal Pouch Anal Anastomosis
Authors: Miller-Ocuin Jennifer L. , Dietz David W. 
Published: November 2022

AbstractThe history of pouch surgery is rooted in surgical innovation to improve quality of life in patients requiring surgical extirpation of the colon and rectum. From the early straight ileoanal anastomosis to the continent ileostomy to the modern ileal pouch anal anastomosis (IPAA), techniques have evolved in response to pitfalls in design. Optimal IPAA design and construction have changed in response to functional outcomes. Nowadays, restorative proctocolectomy with IPAA is the optimal treatment for patients with ulcerative colitis or familial adenomatous polyposis. The J-pouch with stapled anastomosis has become the preferred procedure. Historical configurations and technical pearls, as described in this article, should be considered by surgeons who regularly care for patients requiring ileal pouch surgery.
Interpreting idioms in a second language
Authors: van Dijk Demi , Vogels Jorrig , de Vries Mark 
Published: November 2022

Abstract
How do people understand figurative speech in a foreign language? What strategies do they use? By means of an
online questionnaire, this study investigated to what extent contextual information and transfer play a role in the interpretation
of idioms in a second language, controlling for familiarity. Sixty-one native speakers of Dutch were asked to guess the correct
interpretation of English idioms with and without a Dutch equivalent, presented with and without context, out of four answer
options. The results showed that correctly interpreting an idiom depends on both the presence of context and the possibility of
transfer. More correct interpretations were given when an idiom was presented in a context, but only for English idioms without an
equivalent in the native language. English idioms with an equivalent in Dutch, often rated as familiar, were mostly understood
correctly. We interpret this result as the involvement of transfer from the native language.
The use of the Dutch discourse particle eigenlijk by native and non-native speakers
Authors: van Rossem Naomi , Hogeweg Lotte , de Hoop Helen , Hubers Ferdy 
Published: November 2022

Abstract
In this paper, we investigate whether non-native speakers of Dutch use the interpersonal discourse particle
eigenlijk differently than native speakers of Dutch. Particles such as eigenlijk are considered to be very difficult to learn for
non-native speakers. Eigenlijk might be even more difficult to learn than other particles, because of its complex effect on the
discourse. We tested whether non-native speakers of Dutch used eigenlijk differently than native speakers of Dutch by means of an
online cloze test in which native speakers (control group, N = 109) and non-native speakers
(N = 73) had to choose between eigenlijk and an adverb in a variety of contexts. Results indicated that
non-native speakers used eigenlijk differently than native speakers, but non-native speakers did somewhat understand that
eigenlijk marks a contrast with a contextually raised expectation. Moreover, more proficient native speakers were more similar to
native speakers in their use of eigenlijk than less proficient native speakers.
Multimodality as civic participation
Authors: de Groot Freek Olaf , Jocuns Andrew 
Published: November 2022

Abstract
In October 2018, a collaboration between young rap artists in Thailand’s Indy rap scene, Rap Against Dictatorship (RAD), launched a video criticizing the ruling Junta that went viral within days of publication. The Junta soon after released its own video as a response to RAD. The production and publication of both videos are what Scollon (2001) calls social actions mediated by a distinct cultural toolkit. This study analyzed how modes such as music, text, color, camera angle, gestures, voice, image and iconicity emerged in both videos to realize scalar differences in civic participation. The Junta’s video represents a high sociolinguistic scale, whereas RAD realizes a lower scale. In a time of political unrest in Thailand, sociolinguistic scale and the semiotic resources that people employ to realize scales are a lens to analyze how different stakeholders address various perspectives of the political situation and appeal to different levels of civic participation.
Visions of the good future
Authors: Friberg Anna 
Published: November 2022

Abstract
The relationship between time and politics is complex and multilayered, especially in issues such as global
warming. This facilitates political playing with and about time; political actors use and frame time in various ways. Drawing upon
the work of Reinhart Koselleck, this article examines temporal statements about the environment and the climate in Swedish
election campaigns 1988 to 2018 and shows how political rhetoric has been constituted by several competing modalities of time.
However, these modalities can become problematic for political thinking about the future. To resolve the climate crisis, we need a
politics that acknowledges both historical and political contingency. Engaging with the past, without seeking to extrapolate a
unified narrative of historical progress, explores the past from various perspectives and shows how the present is contingent.
This could enable a renegotiation of possible futures and a politics for the future that facilitates both understanding and
action.
Is it Possible to Use the HCR-20 V2 to Assess the Risk of Violent Recidivism of French Offenders?
Authors: Bertsch Ingrid , Courtois Robert , Gallard Elodie , Réveillère Christian , Pham Thierry H. 
Published: November 2022

Abstract
The Historical-Clinical-Risk Management Scale 20 (HCR-20) is a structured tool to assess the risk of violence and assist in its management. French professionals are reluctant to use it because only a few studies have shown its psychometric qualities with French samples. The objective of this study is to test the psychometric qualities of the HCR-20 with samples of violent detainees in France. The HCR-20 and Level of Service/Case Management Inventory (LS/CMI) were administered to 128 violent offenders with an average age of (44.16±12.30) years. We evaluated the reliability, internal consistency and validity of the HCR-20 and conducted an exploratory factor analysis. The results show that the HCR-20 has good psychometric qualities with a sample of French prisoners. Only the Risk domain presents weak results due to the data collection locations and the participants’ age. Correlations were observed between certain factors. The exploratory factor analysis shows four factors explaining 44% of the variance. The continuation of this work will enable French professionals to use sound tools to assess the risk of recidivism.
Recovering the fragmentation rate in the growth-fragmentation equation
Authors: Almeida Gomez Alvaro , Zubelli Jorge P 
Published: November 2022

Abstract
We consider the inverse problem of determining the fragmentation rate from noisy measurements in the growth-fragmentation equation. We use Fourier transform theory on locally compact groups to treat this problem for general fragmentation probabilities. We develop a regularization method based on spectral filtering, which allows us to deal with the inverse problem in weighted

L

2

spaces. As a result, we obtain a regularization method with error of order

O
(

ε

2
m

2
m
+
1

)

, where ɛ is the noise level and m > 0 is the a priori regularity order of the fragmentation rate.