bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of self-tapping and self-drilling screws in open reduction of mandible fracture
Authors: SANCAR Bahadır , ÜSTÜNDAĞ İrfan 
Published: March 2022

Objective: The purpose of this study is to assess the early postoperative stability of screw systems with mini plates in the treatment of open reduction mandibular angulus fractures.
Material and Method: This study consisted of 3 groups of mini plate or screw fixation: a 1.6 mm diameter drill for Group 1, a 1.2 mm diameter drill for Group 2, and self-drilling screws without drilling in Group 3. We used 9 hemimandibles, 9 plates, and 36 screws in each group. We compared the self-tapping and self-drilling screw systems while maintaining the plate system constant. We generated angulus fractures in 27 hemimandibles taken from 14 sheep mandibles. We separated the samples into 3 groups, each with 9 hemimandibles. All the screws used in the study were 2 mm in diameter and 5 mm in length. We used the servo hydraulic test unit to apply force to the hemimandibles. We applied forces of 10, 20, 30, 40, 50, 60, 70, 80, 90, 100, 110, 120, 130, 140, and 150 N to the hemimandibles and recorded the resulting displacements. Data were analyzed with IBM SPSS V23, and conformity to normal distribution was evaluated by the Shapiro-Wilk test.
Results: There was no difference between the groups in terms of the amount of displacement that occurred as a result of the applied forces.
Conclusion: In the treatment of mandibular fractures with open reduction, surgeons should focus on plate-related parameters rather than self-drilling and self-tapping of screws, or drill diameter.
The effect of altitude difference on gastrointestinal bleeding in the chronic period
Authors: POLAT Esra , İNANÇ İbrahim Halil , ŞABANOĞLU Cengiz 
Published: March 2022

Aim: The susceptibility to gastrointestinal bleeding is observed with an increase in altitude. There is no recommendation regarding altitude in terms of drug selection and dose to be used in diseases requiring antiaggregant and anticoagulant use. In this study, we aimed to determine whether there is a difference between gastrointestinal bleeding requiring hospitalization due to the use of antiaggregant and/or anticoagulant therapy between two populations living at different altitudes.
Material and Method: This retrospective study was performed in two secondary care hospitals. Patients from Group B living in villages with an altitude of 9842 ft and above and Group F patients living in an area with an altitude of 30 ft were included. Patient’s demographic data, co-morbid diseases, antiaggregant and anticoagulant use, hemoglobin, hematocrit, MCV values and platelet count were noted.
Results: The study included a total of 118 patients with gastrointestinal bleeding. There was no statistically significant difference between the groups in terms of the drugs used by the patients, the types and numbers of drugs.
Conclusion: We found that there was no significant difference between the groups with different altitudes in terms of drugs used by patients with gastrointestinal bleeding, drug types and numbers.
Comparison of labral repair and biceps tenodesis concomitant with arthroscopic rotator cuff repair in patients between the age of 40 and 60
Authors: CENGİZ Bertan , OGUZKAYA Sinan 
Published: March 2022

Aim: Superior labrum anterior to posterior (SLAP) lesions are frequently accompanied by rotator cuff tear (RCT). The optimal treatment for type 2 and 4 SLAP lesions with RCT were not established. We aimed to compare the clinical results of SLAP repair and biceps tenodesis (BT) concomitant with arthroscopic rotator cuff repair (ARCR) in patients between 40 and 60 years old.
Material and Method: Forthy three patients (16 male, 27 females) who received ARCR concomitant with SLAP repair or BT for full-thickness rotator cuff tear were evaluated retrospectively. The patients were divided into the two groups based on treatment methods (SLAP repair, Group 1, 20 patients), (BT, Group 2, 23 patients). American Shoulder and Elbow Surgeons (ASES) score, University of California Los Angeles (UCLA) shoulder score, visual analogue scale scores (VASs), and range of motion (ROM) values were used as outcome tools.
Results: The mean age of the patients was 48.8±5.03 years. There was no difference in preoperative shoulder and pain scores (P
Effects of blood group types on risk of infection, disease severity, and mortality in COVID-19 patients
Authors: GEMCİOĞLU Emin , BAŞER Salih , İNAN Osman , ASFUROGLU KALKAN Emra , GULER Bagdagul , KARAAHMETOĞLU Selma , HASANOĞLU İmran , GÜNER Rahmet , COPUROGLU Esra , ATEŞ İhsan 
Published: March 2022

Aim: COVID-19 is an epidemic communicable disease that has been declared as a pandemic caused by severe acute respiratory syndrome coronavirus 2. Clinical studies have demonstrated that advanced age and comorbid conditions enhance the severity of the infection. The objective of this study was to examine the of effects of blood group types on risk of infection, disease severity, and mortality in COVID-19 patients.
Material and Method: Included in this study were 1618 patients who had been diagnosed with PCR confirmed COVID-19 infection. The age, gender, blood type, disease severity, need for intensive care, and deaths of the patients were analyzed retrospectively. For the distribution of the blood types in a healthy population, statistics for the blood types of individuals in Ankara for 2020 were obtained from the Republic of Turkey Red Crescent Blood Services and used as a healthy control group for comparison with the data of the patients included in the study.
Results: Among the COVID-19 patients, blood type A was the most common type at a rate of 46.2%. This was followed by blood type O at a rate of 28.4%. The least common blood type was found to be type AB at a rate of 9%. When compared to the healthy population, blood type A was determined to be statistically significantly more common in COVID-19 infection (p=0.07,). In contrast, blood type O was determined to be less common when compared to the healthy population (p
The role of inflammatory markers derived from complete blood count results in the diagnosis of intrahepatic cholestasis of pregnancy
Authors: IRAK Kader , BAYRAM Mehmet , BECERİK Tüba Fikriye 
Published: March 2022

Objective: This study aimed to investigate complete blood count (CBC) markers, particularly those indicating systemic inflammation, in healthy subjects and those with mild and severe intrahepatic cholestasis of pregnancy (ICP).
Material and Method: Seventy-nine subjects with ICP and 100 healthy age-matched women who were matched based on their scheduled singleton deliveries (on the same day) were included. ICP was defined as the increase in serum bile acid levels ≥10 μmol/L coupled with pruritus which could not be explained by other conditions. Patients with ICP were further categorized to mild and severe ICP according to bile acid levels, as follows: Mild ICP (
Smartphone-based videoconference visits are easy to implement, effective, and feasible in Crohn's disease patients: a prospective cohort study
Authors: YILMAZ Hasan , DUMAN Ali Erkan 
Published: March 2022

Aim: Crohn's disease patients require life-long follow-up resulting in frequent hospital visits. The benefits of telehealth have been established in the remote management of Crohn’s disease but the role of mobile technology is missing. Our goal was to determine the feasibility and effectiveness of smartphone-based real-time video visits.
Material and Method: We followed 139 patients with either traditional (FTF) or online clinics (OLV) at a university hospital between May 2020- December 2020. We measured patients' satisfaction, disease activity, visit outcomes, socioeconomic parameters, and travel expenses to assess the effectiveness and acceptance of OLV.
Results: Satisfaction scores were significantly higher at OLV compared to FTF (89.58±9.93 vs 70.85±18.51, p
Relationship of the CRP/albumin ratio and the systemic immune-inflammation index with Forrest classification in patients with gastrointestinal bleeding
Authors: BOZAN Öner , ATİŞ Şeref Emre 
Published: March 2022

Aim: The present study aimed to investigate CRP/albumin ratio and the systemic immune-inflammation index (SII) and Forrest classification in patients who presented to the emergency department with acute upper gastrointestinal (GI) bleeding.
Materials and Method: Patients over 18 years of age who presented to the emergency department of our hospital with melena, hematemesis, and hematochezia and were diagnosed with upper GI bleeding via esophagoduodenoscopy were included in the study. Esophagoduodenoscopy results, and accordingly, the Forrest classifications, together with complete blood count, including hemoglobin, platelet, and neutrophil values, as well as demographic characteristics were recorded. SII (calculated by multiplying the platelet count with neutrophil count and dividing the value obtained by the lymphocyte count [platelet (P)×neutrophil (N)/lymphocyte (L)]) and CRP/albumin ratio was calculated.
Results: No statistically significant difference was observed among the Forrest classification groups in terms of the median SII values as well as median CRP/albumin ratios. However, a statistically significant difference in median CRP/albumin ratios was observed among the dichotomized Forrest classification groups.
Conclusion: The SII is not a reliable parameter either predicts GI bleeding or the Forrest classification in patients with upper GI bleeding. The CRP/albumin ratio might be a poor predictor of bleeding; however, it can not predict the Forrest classification.
Temperament and character traits in young men diagnosed with idiopathic scoliosis
Authors: MADEN Özgür , UMUR Levent , AKTAŞ Selman , ORHAN Serdar , YILDIRIM Cengiz 
Published: March 2022

Introduction: The aim of this study is to examine whether the temperament and character traits of young men diagnosed with idiopathic scoliosis (IS), known as the three-dimensional deformity of the spine and trunk, which begins to emerge during the growth period and progress with changes in the quality of life in adulthood, are different from those without idiopathic scoliosis.
Material and Method: A total of 162 IS and 162 healthy male individuals were included in the study. Scoliosis level was evaluated with the Cobb method and temperament and character traits were evaluated with the Temperament and Character Inventory. The data were evaluated with SPSS ver.22.0 program and p
COVID-19 pandemic: depression and sleep quality in hemodialysis patients
Authors: YAVUZ Demet , DOĞRU BALAKBABALAR Ayşe Pınar , DEMİRAG Mehmet Derya , SEZER Siren 
Published: March 2022

Introduction: Depression and sleep disturbance are prevalent comorbidities in hemodialysis patients. This study aimed to investigate the relationship between depressive mood, sleep disturbance, and the fear of COVID-19 Scale in hemodialysis patients during the pandemic process.
Material and Method: 116 hemodialysis patients followed up in our clinic and volunteered were included in the study. The socio-demographic characteristics of the patients and the laboratory test results studied in their routine follow-ups were obtained from the file records. Beck Depression Inventory (BDI), Pittsburgh Sleep Quality Index (PSQI), and the Fear of COVID-19 Scale (FCV-19S) were applied through face-to-face interviews.
Results: 116 patients (70 males, 46 females) with a hemodialysis duration of 40 months (13-295) and age of 60.2±13.3 years were included in the study. The patients were divided into two groups according to their PSQI score as good sleeper (PSQI ≤ 5, n=66) and poor sleeper (PSQI >5, n=50). When evaluated by gender 28 (56%) female patients were in the poor sleeper group (p=0.002). Dialysis time was longer, BDI score and FCV-19 scale were higher in the poor sleeper group than the good sleeper group. PSQI score was positively correlated with dialysis time (r=0.259 p=0.005), BDI score (r=0.279 p=0.002), and FCV-19 scale (r=0.304 p=0.001). In the Multiple Logistic Regression analysis established to evaluate the risk factors affecting sleep quality, BDI was determined as an independent risk factor for poor sleep (OR: 1.084, 95%CI [1.021-1.152], p=0.008). Subjects were divided into two groups according to their BDI scores as those with depressive mood (BDI score ≥ 17, n=47) (40.5%) and those without (BDI score < 17, n=69) (59.5%). Thirty-two of the cases with depressive mood were women (68.1%) (p
Comparison of the in vitro Demodex folliculorum killing activity of azelaic acid and permethrin
Authors: BOTSALİ Ayşenur , YÜREKLİ Aslan 
Published: March 2022

Aim: Demodex parasites have been linked to dermatological disorders, especially rosacea, without a proven mechanism. Moreover, some anti-Demodex agents demonstrate a dual therapeutic effect related to a direct effect on the skin disorder along with a decreased number of Demodex mites. Despite being considered a first-line treatment approach for rosacea, azelaic acid's efficacy against Demodex mites has not been investigated. In the current study, mites were continuously observed after exposure to the test agents to evaluate the potential anti-Demodex efficacy of azelaic acid. The efficacy of azelaic acid was compared to that of a positive control agent (permethrin).
Material and Method: The wastes of diagnostic standardized skin surface biopsy samples of rosacea patients were collected for the trial. To four active treatment groups were administered 10% azelaic acid, 20% azelaic acid, 30% azelaic acid, and 5% permethrin. In addition, there was a control group, and 20 Demodex mites were included in each of the five groups. The authors conducted the real-time observation of the study groups through a digital microscope. The survival times of the mites were recorded and compared between the groups.
Results: The mean survival time was 12.2±1.5 minutes in the 5% permethrin group. The mean survival times in the 10%, 20%, and 30% azelaic acid groups were 15.8±1.6, 14±1.5, and 12±1.2 minutes, respectively. The differences between the four active treatment groups did not reach statistical significance (p>0.05).
Discussion: The present study’s results revealed that all three concentrations of azelaic acid had anti-Demodex efficacy comparable to that of 5% permethrin.
The effect of colchicine treatment on complete blood cell count-based parameters in patients with Behçet's disease
Authors: TEZCAN Dilek , TURAN Çağrı , YİLMAZ Sema 
Published: March 2022

Aim: Behçet's disease (BD) is a systemic disease, with still unknown etiology and pathogenesis and varying disease presentations, characterized by recurrent oral aphthae, followed by genital ulcers, arthritis, variable skin and ocular lesions, gastrointestinal and central nervous system involvement, as well as, vascular disease. Colchicine is one of the oldest remedies still in use today. The study aimed to investigate the effect of colchicine on levels of the complete blood cell count-based parameters in BD.
Material and Method: A total of 117 (participants 60 healthy control and 57 patients with BD) were recruited from the rheumatology department in a single-center case-control study. The laboratory data were obtained from the electronic registration database. Laboratory findings of patients and healthy controls were evaluated. In addition, patients with BD were evaluated for these parameters before colchicine therapy and after 3-month from the beginning of colchicine treatment.
Results: The levels of inflammatory markers such as neutrophil count, neutrophil to lymphocyte ratio (NLR), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and systemic immune-inflammation index (SII), significantly higher than the control group before treatment, decreased to similar levels with the control group in the third month of colchicine use. However, red blood cell distribution width (RDW), mean platelet volume (MPV), and plateletcrit (PCT) were still statistically significantly different from the control group in BD patients.
Conclusion: SII, CRP, ESR, and NLR are useful parameters to evaluate the colchicine response of patients with mucocutaneous BD.
The effect of the COVID-19 pandemic on the increase of hyperlipidemia and metabolic syndrome in the Turkish population: a retrospective study
Authors: KARABULUT Alpaslan , ŞAHİN Mustafa 
Published: March 2022

Aim: With the Coronavirus Disease 2019 (COVID-19) pandemic starting in late 2019 and continuing into 2020, permanent or periodic quarantine processes and curfews have been implemented. The objective of the study was to investigate the impact of extended quarantine processes during the pandemic on the development of metabolic syndrome (MET-S) due to physical inactivity.
Material and Method: This retrospective study consists of two groups. The first group consists of patients who applied to our hospital in the 12 months preceding the pandemic. The second group consists of the same patients who applied to the same hospital within 12 months of the onset of the pandemic. A total of 44,024 participants who had lab data prior to and during the pandemic were included in the study. Fasting plasma glucose (FPG), Triglyceride (TRIG), Total Cholesterol (T-Chol), High Density Lipoprotein-Cholesterol (HDL-C), Low Density Lipoprotein-Cholesterol (LDL-C) levels and demographic characteristics of the patients were recorded. The test averages were compared between the two groups and their effects on the development of MET-S were subjected to statistical analysis.
Results: When we compared our patients' HDL-C, FPG and TRIG levels measured during the pandemic and the pre-pandemic period, we found a statistically significant increase (p100 mg/dL and TRIG>150 mg/dL during the pandemic was statistically significantly higher than during the pre-pandemic period (51.7% vs 45.8%, p
Severity of subchondral insufficiency knee fracture: is it associated with increasing age, femorotibial angle, and severity of meniscus extrusion?
Authors: BALTA Orhan , ŞAHİN Kübra , ZENGİN Çağatay , EREN Mehmet Burtaç , ALTINAYAK Harun , DEMİR Osman 
Published: March 2022

Aim: To evaluate the relationship between severity of subchondral insufficiency fracture of the knee (SIFK) and age, gender, knee alingment, meniscus tear, type and location, severity of meniscus extrusion, and degree of knee osteoarthritis.
Material and Method: This retrospective study included 308 patients with SIFK seen on MRI. SIFK lesions were categorized as grade 1 to 4, with distinction between low grade (1 and 2) and high grade (3 and 4). The relationships between SIFK grade and patients' age, body mass index (BMI), femorotibial angle (FTA), meniscus tear,type and location meniscusextrusiongrade and osteoarthritis (grade 0 to grade 4) evaluated.
Results: According to the gender, 39.3% were men and 60.7% were women. The distrubutin of the SIFK grades were respectively 42.2% grade 1, 30.8% grade 2, 22.7% grade 3 and 4.2% grade 4. FTAwas positively correlated with SIFK grade (from grade 1 to grade 4, respectively; 4.42±2.57, 5.09±2.26, 5.74±2.78 and 5.95±2.54) (p=0.002). No statistically significant difference was observed between height, weight and BMI and the degree of SIFK.The mean FTA was 4.99±2.57° in SIFK. The FTA angles showed a stastistically significance between low (4.73±2.48°) and high (5.71±2.69°)grade SIFK (p:0.003). Roc analysis showed that the FTA above 3.1° and the age above 52 year old were at risk. The mean extent of meniscal extrusion was larger in high grade SIFK (p=0.001). Multivariable logistic regression analysis showed that compared with low grade SIFK, high grade SIFK was more closely associated with age, FTA, lateral meniscus extrusion and medial meniscus tear type.
Conclusion: High-grade SIFK lesions are associated with higher FTA and older age. In particular, patients with acute knee pain, older than 52 years of ageanda higher FTA than 3.1°, we recommend to perform knee MRI if possible.
Our convalescent plasma experiences in COVID-19 patients hospitalized in the intensive care unit
Authors: GÜVEN Bülent Barış , ERTÜRK Tuna , YILDIZ Egemen , DURMAYÜKSEL Esra , ERSOY Aysin , TANOĞLU Alpaslan 
Published: March 2022

Objective: Despite vaccine and drug studies, convalescent plasma (CP) therapy remains an alternative treatment for coronavirus disease 2019 (COVID-19). In this study, we aimed to reveal the efficacy of CP therapy on mortality and the factors affecting it for the patients diagnosed with COVID-19 and acute respiratory distress syndrome (ARDS) which were followed in our intensive care unit (ICU).
Material and Method: The data (demographic characteristics, the amount of CP used, PaO2/FiO2, leukocyte, neutrophil, lymphocyte, D-Dimer, C-reactive protein (CRP), procalcitonin, ferritin values, and the clinical findings) of the patients who were hospitalized in the ICU with the diagnosis of COVID-19 and received CP treatment between 20 March and 20 October 2020 were analyzed retrospectively. Data of deceased patients (n=29) and survivors (n=50) were compared with each other and logistic regression analysis was performed to investigate the relationship with mortality.
Results: 79 patients who received 166 units of CP therapy after a mean of 13.45±3.6 days symptom onset, were identified. 96.2% of the patients had at least one concomitant disease. Mortality was observed in 29 (36.7%) of the patients. Mortality (5.1%) was less common in those receiving CP therapy within the first 14 days after the onset of symptoms. Patient age (p=0.041), neutrophil/lymphocyte ratio (p=0.004), CRP values (p=0.002), the number of comorbidities (p
Evaluation of the health literacy level of the patients who applied to a tertiary hospital family medicine clinic
Authors: PALA Emin 
Published: March 2022

Aim: This study aimed to reveal the level of health literacy of the patients who applied to the family medicine clinic of a tertiary hospital in Turkey and its relationship with demographic parameters.
Material and Method: This study is a cross-sectional descriptive study. Study conducted in the family medicine clinic of an education hospital. Demographic characteristics and health literacy levels of the participants such as age, gender, marital status, educational status, professions, and financial status were noted. The health literacy levels of the participants were determined by using the Turkish Health Literacy Scale-32.
Results: A total of 443 participants were included in the study. the median age of the participants was 36. The median health literacy of the participants was 33.9 (25th and 75th quartiles: 29.2-40.8). The health literacy index of 57 (12.9%) participants were inadequate 139 (31.4%) participants was problematic, 147 (33.2%) participants were sufficient, and 100 (22.6%) participants was excellent. There was a statistically significant, negative, and weak correlation between age and health literacy index. (r=-0.200, p=0.01, Spearman correlation test).
Conclusion: Low health literacy is an important public health problem. Health literacy can be considered a priority policy issue. Legal arrangements can be made to carry out activities for health literacy.