bluuebunny/crossref_metadata_2025_split huggingface dataset:
РЕЖИМЫ РАБОТЫ УСТАНОВОК ЭЛЕКТРОПИТАНИЯ ЦЕНТРОБЕЖНЫХ НАСОСОВ С МНОГОУРОВНЕВОЙ ШИРОТНО-ИМПУЛЬСНОЙ МОДУЛЯЦИЕЙ
Authors: Михальченко Сергей Геннадьевич , Тимошкин Вадим Владимирович , Воронина Наталья Алексеевна , Семенов Сергей Михайлович , Попов Семен Семенович , Афанасьев Кирилл Сергеевич 
Published: August 2022

Актуальность исследования обуславливается необходимостью улучшения показателей качества выходных напряжения и тока автономных инверторов напряжения в установках электроцентробежных насосов, применяющихся в нефтедобыче. К основным факторам, позволяющим повысить эти показатели качества, можно отнести: использование перспективных топологий силовой части и современных силовых полупроводниковых ключей, внедрение новых алгоритмов управления. В электроприводах, где применяются частотные преобразователи, возникают негативные факторы, влияющие на функционирование нефтепогружного кабеля и погружного асинхронного двигателя. Несинусоидальность напряжений на выходе преобразователя частоты приводит к повышенному износу изоляции питающей кабельной линии, а также негативно влияет на изоляцию обмоток асинхронного двигателя и снижает показатели качества систем управления электроприводом. Следовательно, поиск путей для улучшения качества выходного напряжения и тока автономных инверторов напряжения в установках электроцентробежных насосов является актуальной задачей. Цель: разработка алгоритмов для улучшения показателей надежности работы многоуровневых преобразователей и повышение качества гармонического состава выходного напряжения и тока автономных инверторов напряжения в составе электропривода погружного нефтедобывающего насоса. Объект: автономные инверторы напряжения в составе электропривода погружного нефтедобывающего насоса. Методы и средства: теория надежности, гармонический анализ, функциональные схемы, коммутационные функции, топология электрических цепей силовых преобразователей, численные методы решения дифференциальных уравнений, быстрое преобразование Фурье, Matlab Simulink. Результаты. Продемонстрировано значительное улучшение показателей качества тока и напряжения в многоуровневых преобразователях в составе электропривода погружного нефтедобывающего насоса. Рассмотрены возможные способы повышения показателей надежности путем изменения варианта компоновки топологии схемы, при этом вероятность безотказной работы по сравнению с классической компоновкой повысилась с 23,70 до 66,10 %. Установлено, что регулирование частоты коммутации в зависимости от режимов работы в многоуровневых инверторах позволит рационально управлять динамическими потерями и нагрузками на силовые ключи.
Peran Masyarakat dalam Menarik Minat Kunjungan Wisatawan: Studi di Kampung Adat Prailiu Kabupaten Sumba Timur
Authors: Afifa Putri Nur Aini , Nugroho M. Setyo 
Published: August 2022

This study aims to find out how the role and strategy of traditional village community prailiu attract tourist visit interest in east sumba regency. This study uses descriptive qualitative approach with three data collection techniques. First, field observation in traditional village Prailiu. Second, Interview with informants (pusposive sampling). Third, documentation that is related to traditional village prailiu. Data analysis technique uses SWOT analysis to formulate traditional village community strategy prailiu in attracting tourist visit interest in east sumba regency. This study shows that traditional village community has firm desire and commitment in developing tourism village. Then, there are a number of alternative strategies that have been formulated to attract tourist visit interest based on SWOT analysis namely : (1) S-O strategy such as tourism product development, Having a partnership with sector private, Increasing production quality of Tenun (woven fabric), increasing promotion and marketing. (2) S-T strategy such as making tourism package and conducting strengthen product packaging. (3) W-O strategy such as developing SDM, having partnership between woven fabric craftsman and expanding woven fabric marketing network. (4) W-T Strategy such as constructing public awareness, making serftification CHSE, providing health protocol training and providing training about tourism village management.
Analisis Prediksi Motion Sickness Incidence (MSI) Pada Kapal Penyeberangan Di Perairan Makassar
Authors: Bawias Ishak , Lungari Fitria , Risal Risal 
Published: August 2022

Motion sickness pada kapal dikenal juga dengan istilah mabuk laut, mabuk laut adalah gejala sakit yang diakibatkan karena gerakan kapal yang mengakibatkan gejala fisik yang tidak nyaman yang ditandai dengan susah bernafas, pusing, mual ,pucat dan muntah. Penyebab utama mabuk laut adalah tidak adanya kesamaan rangsang atau conformity antara stimulus, mata dan labirin telinga yang diterima oleh otak manusia. Arah datang gelombang sangat berpengaruh terhadap stabil atau tidaknya kapal yang ditumpangi. Metode penelitian menggunakan simulasi software motion kapal. Hasil penelitian menyimpulkan bahwa, kondisi kapal stabil ditunjukkan oleh gelombang yang datang dari arah 0 atau kondisi kapal berlayar searah dengan gelombang yang datang. Sehingga, diprediksikan tidak ada penumpang yang mengalami mabuk perjalanan. Sedangkan kondisi kapal tidak stabil ditunjukkan oleh kapal dengan arah gelombang 180 atau kondisi kapal berlayar berlawanan dengan arah datangnya gelombang. Sehingga diprediksikan penumpang akan mengalami mabuk laut setelah 2 jam perjalanan.
Pengaruh Performa Turbocharger Terhadap Kinerja Mesin Induk Di MT. Green Park
Authors: Marsudi Sugeng 
Published: August 2022

Mesin Penggerak Utama (MPU) atau Mesin Induk di atas kapal merupakan sebuah mesin yang berfungsi untuk menggerakkan kapal maju dan mundur. MPU memiliki dua sistem pemasukan udara pembakaran ke dalam silinder yaitu sistem pemasukan hisap yang mengandalkan kevakuman ruang bakar akibat gerakan piston atau dengan sistem pemasukan tekan yaitu dengan melengkapi mesin dengan Turbocharger. Tujuan utam Turbocharger, menaikkan tekanan udara pembakaran dengan cara mengkompresi udara tersebut sehingga massa aliran udara masuk ruang pembakaran menjadi lebih tinggi dibandingkan udara atmosfir. Jika massa aliran udara pembakaran menurun yang disebabkan oleh berbagai kondisi, maka akan berpengaruh pada proses pembakaran yang tidak sempurna yang secara visual bisa ditandai dengan asap yang berwarna lebih hitam. Pembakaran yang tidak sempurna akan mempengaruhi daya dan kinerja mesin diesel tersebut.
Association of lower back pain(LBP) and knee osteoarthritis(KOA); a systematic review
Authors: Amarasinge Piyumi Lakmali , Wadugodapitiya Surangika , Weerasekara Ishanka 
Published: August 2022

Abstract
Background: Osteoarthritis and lower back pain (LBP) are among most common health problems worldwide leading pain and disability. The purpose of this study was to systematically review the evidence to find any association between knee osteoarthritis (KOA) and LBP.Methods: The databases of Scopus, Medline and EMBASE were searched from inception to 22.02.2021. Any study published in English assessing live humans over 18 years with KOA and LBP were eligible to be included. Data were independently assessed by two researchers. Data were extracted based on the participants, outcomes related to knee, outcomes related to lumbar spine, association between LBP and KOA and study design approach. Results: Of 8620 titles and abstracts, duplicates were removed and 6219 were screened. Altogether 87 full texts were screened and 12 were eligible for the final inclusion.Conclusions: There were some biomechanical and clinical associations observed between LBP and KOA. High pelvic incidence is a risk factor for development of spondylolisthesis and KOA. Development and progression of KOA in patients with degenerative spondylolisthesis may be induced by significantly greater mismatches of lumbo-pelvic sagittal alignment. Elderly patients with degenerative lumbar spondylolisthesis and comorbid severe KOA reported a different pelvic morphology, increased sagittal malalignment with a lack of lumbar lordosis due to double-level listhesis, and greater knee flexion contracture than in patients with no to mild and moderate KOA. Knee pain intensity was higher in KOA when presents with LBP. People with concurrent LBP and KOA have reported poor function with more disability. Assessing both back and knee joints should be considered when treating KOA and vice-versa, to clinically manage, and to prevent further progression. High quality RCTs with a long-term follow-up should be designed to assess the exercise programs consist of both lumbar and knee exercises for these patients. Systematic review registration: PROSPERO (CRD42022238571)
Those who speak survive: The value of the verbal component of GCS in trauma
Authors: Cevik Arif , Alao David , Alyafei Eman , Abu-Zidan Fikri 
Published: August 2022

Abstract
Aim: To evaluate the predictive value of the individual components of GCS in predicting the survival of trauma patients on arrival in the emergency department. Methods: This is a post-hoc analysis of previously published data on trauma patients in Al Ain City. We obtained data on patients that presented with trauma to Al-Ain Hospital who were admitted for more than 24 hours or died at the Emergency Department or hospital from January 2014 to December 2017. Studied variables included demographics, vital signs, Glasgow Coma Scale (GCS), GCS components, Injury Severity Score (ISS), and in-hospital mortality. We entered factors found to have a p value of <0.1 in univariate analysis into a direct logistic regression model to define factors that predict survival.Results: There were 3519 trauma patients in the registry. The median (range) of age, respiratory rate, and ISS were significantly lower in patients who survived 31(0-105) versus 37 (1-76) years, p = 0.031; 18 (6-56) versus 22 (0-35) breaths per minutes, p = 0.019, and 4 (1-75) versus 16.5 (1-75), p < 0.001, respectively). Systolic blood pressure and GCS were significantly higher in patients who survived (median (range) 133 mmHg (21-265) versus 117mmHg (0-209), p = 0.003, and 15 (3-15) versus 6 (3-15), p < 0.001, respectively). Logistic regression analysis revealed that ISS and GCS-Verbal Response (GCS-VR) were significant predictors of survival. GCS-VR was the most significant predictor for survival, with Area Under the Curve of 0.89, p < 0.001.Conclusion: In general trauma patients, acute trauma care professionals can use GCS-VR to predict survival instead of the total GCS score or ISS.
Development of lacrimal gland organoids from iPSC derived multizonal ocular cells
Authors: Asal Melis , Koçak Gamze , Sarı Vedat , Reçber Tuba , Nemutlu Emirhan , Utine Canan Aslı , Guven Sinan 
Published: August 2022

Abstract
Background
Lacrimal gland plays a vital role in maintaining the health and function of the ocular surface. Dysfunction of the gland leads to disruption of ocular surface homeostasis and can lead to severe outcomes. Approaches evolving through regenerative medicine have recently gained importance to restore the function of the gland. The aim of this study is to use tissue engineering strategy to develop a functional lacrimal gland from human induced pluripotent stem cells (iPSCs).
Methods
Using human iPSCs, we generated functional in vitro lacrimal gland organoids by adopting the multi zonal ocular differentiation approach. We differentiated human iPSCs and confirmed commitment to neuro ectodermal lineage, following ocular differentiation. Gene expression and protein levels were measured at several time points up to 45 days for differentiation.
Results
We identified emergence of mesenchymal and epithelial lacrimal gland progenitor cells by the third week of differentiation. Differentiated progenitors underwent branching morphogenesis in the following weeks, typical of lacrimal gland development. We were able to confirm the presence of lacrimal gland specific acinar, ductal, and myoepithelial cells and structures during weeks 4–7. Further on, we demonstrated the role of miR-205 in regulation of the lacrimal gland organoid development by monitoring miR-205 and FGF10 mRNA levels throughout the differentiation process. In addition, we assessed the functionality of the organoids using the β-Hexosaminidase assay, confirming the secretory function of lacrimal organoids. Finally, metabolomics analysis revealed a shift from amino acid metabolism to lipid metabolism in differentiated organoids.
Conclusions
These functional, tear proteins secreting human lacrimal gland organoids harbor a great potential for the improvement of existing treatment options of lacrimal gland dysfunction and can serve as a platform to study human lacrimal gland development and morphogenesis.
Characterization of an Italian landrace of Cyclanthera pedata (L.) Schrad. of herbal and horticultural interest
Authors: Zuccolo Marco , Pedrali Davide , Leoni Valeria , Borgonovo Gigliola , Bassoli Angela , Giorgi Annamaria , Giupponi Luca 
Published: August 2022

Abstract
Caigua (Cyclanthera pedata (L.) Schrad.) is a native species of the Andes whose fruits are recently gaining attention as herbal and healthy product. A genotype of Caigua traditionally cultivated in Camonica Valley (Italian Alps), called “Ciuenlai” (or “Milione/Milioncino”), is almost unknown. For this reason, the phytochemical, nutritional and ecological (functional strategy) characterization of “Ciuenlai” was carried out. Phytochemical and nutritional analyses were performed considering its fruits, leaves, sprouts, and seeds, and compared with commercial South American plant material. Fruits of “Ciuenlai” showed a similar content of phenolic compounds but a lower content of saponins and flavanones and dihydroflavonols than the comparison samples. Conversely, the content in caffeoylquinic acid (frequently considered a quality marker for herbal use) was four times higher for “Ciuenlai” (0.64 ± 0.04%) comparing with the commercial genotype grown in the same area (0.15 ± 0.01%). Interestingly, leaves and sprouts of “Ciuenlai” resulted rich in secondary metabolites, including saponins and flavanones and dihydroflavonols, suggesting that these parts could be eligible for herbal use. Considering the ecological and agronomical features, “Ciuenlai” showed a more ruderal strategy, and different growth, producing more fruit earlier in the season, much smaller than the South American genotype. “Ciuenlai” could have developed an ecological adaptation to the peculiar climatic conditions of the mountain areas of Camonica Valley, different from the native area. The herbal use of “Ciuenlai” could be a useful strategy for its valorisation, other than the promotion of this product as typical food.
Parallel MS-Kmeans clustering algorithm based on MapReduce
Authors: Li Guodong , Wang Chunhong , Li Kai 
Published: August 2022

Abstract
Aimed at the problems of initial points selection, outliers influence and cluster instability of traditional K-means algorithm in big data clustering, an MS-Kmeans algorithm based on MapReduce framework was proposed. The algorithm selected multiple non-outlier points as the candidate center points, and mean shifted the candidate center points, used the maximum-minimum principle to select K initial center points from the candidate center points, and then executed the K-means algorithm to find the final center points. In order to improve the running speed of the algorithm for clustering large data sets, the algorithm used MapReduce framework to implement parallel computing on Hadoop platform. The experimental results showed that the parallel MS-Kmeans algorithm is feasible in big data clustering, and the algorithm performs well in terms of performance, speed and stability
Changes in pelvic tilt related to body position measured with Smart Navigated Ultrasound mobile system
Authors: Kochman Andrzej , Morawska-Kochman Monika , Kozak Jozef , Daniol Mateusz , Sibiński Marcin 
Published: August 2022

Abstract
The aim of the study was to assess the changes of pelvic tilt between standing and supine position with the Smart Navigated Ultrasound (SNU) mobile system. In this prospective study, the pelvic tilt in the standing and supine pelvis was recorded in 16 orthopedically healthy female volunteers, mean age 37.5 years. All measurements were performed with SNU mobile system, consisting of a smartphone-based optical tracking device, medical-grade tablet, an ultrasound device with a transducer, and two rigid body optical markers. Anterior pelvic tilt was noted in all but two patients in the standing position and in all but one in the supine position. For 13 subjects, the pelvis rotated posteriorly during movement from the supine to standing position, in three cases, the change was in the opposite direction. Mean anterior pelvic tilt significantly reduced from lying down (-9.8) to (-4.9) standing (p = 0.04). The study showed that pelvic tilt is different in supine and standing position and is changing from anterior to more posterior, respectively in most cases. The SNU navigation system may be a useful to prevent complications related to cup position due to differences in pelvic tilt between those positions and could be used for large-scale screening purposes.
Dorzagliatin improves glucose-stimulated GLP-1 secretion in T2D and is synergistic with sitagliptin in glycemic control
Authors: Chen Li , Zhang Jiayi , Sun Yu , Zhao Yu , Liu Xiang , Fang Zhiyin , Feng Lingge , He Bin , Zou Quanfei , Tracey Gregory 
Published: August 2022

Abstract
To evaluate the clinical pharmacokinetics and pharmacodynamics of dorzagliatin in glycemic control and glucose sensitivity alone or in combination with sitagliptin in obese T2D subjects. Fifteen obese T2D subjects were treated with sitagliptin 100 mg QD followed by a combination of sitagliptin 100 mg QD with dorzagliatin 75 mg BID at second stage and the third stage of dorzagliatin 75 mg BID alone. Together with improvement in early-phase insulin secretion, an additional 30% glucose-lowering effect was observed in combination (dorzagliatin + sitagliptin) in glucose iAUC0 − 4h. A significant increase of iCmax of glucose-stimulated GLP-1 secretion (GLP-1total) was observed in dorzagliatin monotherapy. The pharmacokinetic GMRs (AUC0 − 24h and Cmax) of dorzagliatin and sitagliptin for combination/either monotherapy fell within 80% -125%. Dorzagliatin regulates glucose-stimulated GLP-1 release and synergizes with sitagliptin in optimizing glycemic control in obese T2D patients. Lack of clinically meaningful pharmacokinetic interactions between dorzagliatin and sitagliptin supports their oral co-administration for diabetes management.
Specialized neuronal modules for economic and single-attribute choice in the orbitofrontal cortex
Authors: Cai Xinying , Xu Chengze , Ni Kuntan 
Published: August 2022

Abstract
An important aspect of biological intelligence is the ability of quick task switching. Such ability may be realized through a neural system equipped with functionally specialized modules subserving each task. The orbitofrontal cortex (OFC) harbors a persistent circuit supporting economic decisions under different contexts. To examine the specialization of this circuit, we contrasted the coding of the same neurons in the OFC of rhesus monkeys under economic choice (EC) and single-attribute choice (SC). In EC, OFC neurons largely encoded offer value, chosen value and choice outcome in goods space. Strikingly, these neurons were tuned out in SC while a complementary set of neurons encoded SC-related variables in a spatial reference frame. Moreover, in EC, neurons encoding the same value-related variable are anatomically clustered and the noise correlation among these neurons dropped significantly when the animal switched from EC to SC, suggesting altered functional organization. Thus, specialized modules in the OFC may support cognitive flexibility in choice.
Net-zero CO2 emissions scenarios for Switzerland
Authors: Panos Evangelos , Kannan Ramachandran , Hirschberg Stefan , Kober Tom 
Published: August 2022

Abstract
Switzerland has one of the lowest CO2 intensities among industrialised countries. The transition to net-zero emissions is further complicated by limited domestic mitigation options, which tend to have high costs, raise energy security concerns, and trigger socio-economic barriers in policy implementation. Research on these issues is also relevant to the societal and political debates on country energy transitions worldwide. We apply robust techno-economic energy systems modelling to highlight the challenges of the Swiss energy transition under different technical, socio-economic, and geopolitical contexts and suggest feasible technical solutions based on low-carbon technologies, efficiency, and flexibility. Import independency and net-zero emissions by 2050 require an additional cumulative discounted investment of 300 BCHF2019 in energy efficiency, domestic renewable and hydrogen technologies. The average per capita costs of net-zero emissions are 320–1390 CHF2019/yr., depending on domestic mitigation options exploitation, integration of Switzerland in international energy markets, energy security and resilience ambition.
An investigation of the shearing performance and sheared surface characterization of Ultra-Strength DP Steel-Al Explosive Welded Plate Composite
Authors: DEMİR Bilge , Ali Khalil Belras , Gürün Hakan , Acarer Mustafa 
Published: August 2022

Abstract
Piercing/blanking-cutting sheet metals with a punch are still the industry's most preferred process. This study previously aimed to fabricate the Ultra Strength DP1200 Steel-AA1100 sheet composite and then research punch shearing performance and surface characterization of this plate composite and original materials. Experimental studies include various applications such as metallography and micro image analysis, explosive welding of DP1200-Al dissimilar materials, punching operations, and tensile testing. Five different shaped punches were used in the Punching process. The force graphs corresponding to the procedure times were obtained thanks to the load-cell computer system. The resulted surface qualities of the cutting edges of the punched samples were evaluated by image analysis using digital and SEM microscopy. Shear analyzes were also performed using Finite element analysis to ensure consistency with experimental studies. As a result, the composite plate of DP1200 steel − 1100 aluminium sheet metals has been fabricated successfully by an explosive welding technic. Besides, the punching results showed good agreement between modelling and experimental punching forces. The highest cutting forces were observed when the punch "0" (flat-punch, 0°). The lowest cutting forces were obtained from the other used punch forms using punch R2, V16, R1, and 16, respectively. Moreover, the punched surfaces have been observed by comparing the force-time graphs. In addition, this study is a pioneer in the literature on its concepts, such as explosive weld materials and their punch process.