bluuebunny/crossref_metadata_2025_split huggingface dataset:
Night shift occupational risk related to breast cancer in nurses: A systematic review. [Riesgo laboral en turno nocturno relacionado al cáncer de mama en enfermeras: Una revisión sistemática]
Authors: Osorio Calle Yuli Pilar , Sebastian Aquino Katterin J. , Rodriguez  Matos Roxana L. , Meneses La Riva Mónica Elisa 
Published: September 2022

Objective: To identify the scientific evidence of occupational risk in night shift related to breast cancer in nurses.
Methods: A review of the literature was carried out by consulting the following databases: PubMed, Science Direct, Scielo and Dialnet. Records were selected from 2012 to 2022, in Spanish, Portuguese and English on the topic of interest.
Results: After critical reading analysis, a total of 16 studies were identified. Most studies report the occupational risk of the nurse is related to breast cancer with night shifts more than 3 per month, melatonin, exposure to artificial light during the night, circadian rhythm among others.
Conclusions: Occupational risks are present, so the nurse in the face of increased risk of cancer should assume preventive-promotional self-care actions to promote their quality of life.
Edukasi Gizi 1000 Hari Pertama Kehidupan (HPK) untuk Meningkatkan Pengetahuan Ibu di Komunitas Kesehatan Keluarga
Authors: Dwijayanti Ira , Wulandari Catur , Mauhibah Farah Uma 
Published: September 2022

Inadequate nutrient intake during the first 1000 days plays a role in increasing multiple nutritional problems and chronic diseases in the future. In addition, the quality of human resources will be hampered due to low cognitive abilities in the long term. The objective of this nutrition education is to increase the mother’s knowledge about the first 1000 days. The education was carried out using presentation and discussion. 121 respondents were members of the family health community. The education is held online once a week in November 2021. The material provided consists of 4 educational sessions, namely (1) Nutrition for pregnancy, (2) Nutrition for breastfeeding mother, (3) Nutrition for infant aged 6-24 months; and (4) The importance of appropriate complementary feeding. The measurement of knowledge was carried out using pre-test and post-test questionnaires. The result showed that 49 participants (40,5%) experienced an increase in knowledge which was indicated by higher score in post-test than pre-test. A total 47 participants (38,9%) had the same score before and after education. Howeverm there were 25 participants (20,6%) who had lower score of post-test than pre-test. An increase in nutritional knowledge is expected to increase the ability to meet the nutritional needs of 1000 HPK. This nutrition education can be continued with nutrition training to improve the ability to meet nutritional needs.
ABSTRAK
Asupan gizi yang tidak optimal pada masa 1000 HPK berperan meningkatkan beban masalah gizi ganda dan penyakit kronis di masa depan. Disamping itu, kualitas sumber daya manusia akan terhambat akibat rendahnya kemampuan kognitif pada jangka panjang. Kegiatan edukasi gizi ini bertujuan untuk meningkatkan pengetahuan ibu tentang 1000 HPK. Kegiatan dilakukan menggunakan metode edukasi ceramah dan diskusi. Peserta terdiri dari 121 orang yang merupakan anggota komunitas dan ikut aktif pada seluruh sesi edukasi. Edukasi dilaksanakan secara daring setiap satu minggu sekali pada Bulan November 2021. Materi yang diberikan terdiri dari 4 sesi edukasi yaitu (1) Asupan gizi optimal pada ibu hami; (2) Asupan gizi optimal ibu menyusui; (3) Asupan gizi optimal bayi usia 6-24 bulan; dan (4) Pemberian MP-ASI yang tepat. Pengukuran peningkatan pengetahuan dilakukan menggunakan kuesioner pre-test dan post-test. Hasil menunjukkan bahwa 49 peserta (40,5%) mengalami peningkatan pengetahuan yang ditunjukkan dengan nilai post-test lebih tinggi daripada nilai pre-test. Sejumlah 47 peserta (38,9%) memiliki nilai nilai yang sama sebelum dan sesudah edukasi. Namun, terdapat 25 peserta (20,6%) memiliki nilai post-test lebih rendah dibandingkan nilai pre-test. Adanya peningkatan pengetahuan gizi diharapkan dapat meningkatkan kemampuan dalam memenuhi kebutuhan gizi pada 1000 HPK. Edukasi gizi ini diharapkan dapat dilanjutkan dengan pelatihan gizi untuk meningkatkan kemampuan dalam memenuhi kebutuhan gizi.
Pemeriksaan Kesehatan Lansia pada Era Pandemik Covid-19 di Panti Sosial Tresna Werdha Provinsi Bengkulu
Authors: Lina Liza Fitri , Fredrika Larra , Angraini Wulan 
Published: September 2022

The level of public health in Indonesia, especially the community is still relatively low, including the community or residents of the Wedha social tresna home, this is because there are still obstacles to carrying out physical health checks that are not strong enough, difficult access to health services. The purpose of this activity is to treat sick residents of the orphanage with curative therapy and can slightly reduce the cost of treatment for the residents of the orphanage. The method used to solve these health problems is to conduct a health examination and provide treatment. This is certainly inseparable from the demands and needs needed by the community, especially the residents of the orphanage. From the free health checks provided, many participated, especially the residents of the orphanage, both the elderly and nursing home staff, there were 57 people who had been given health checks, both cholesterol and blood sugar tests, with the results of an examination for cholesterol of 15.7% which had a score of 15.7%. which is not normal, 10.52% for blood sugar and 33.33% for uric acid. From the health checks carried out, many elderly people were able to take part in the activities, although there were also some that had to be done at their respective guesthouses, due to the limitations of the elderly to walk to the hall where the health checks were carried out.
ABSTRAK
Derajat kesehatan masyarakat di Indonesia terutama masyarakat masih tergolong rendah termasuk masyarakat atau penghuni panti sosial tresna Wedha, Hal tersebut diakibatkan karena masih adanya kendala lansia untuk melakukan pemeriksaan kesehatan kendala fisik yang kurang kuat, sulitnya akses terhadap pelayanan kesehatan. Tujuan dilaksanakan kegiatan ini adalah untuk mengobati warga panti yang sakit dengan terapi kuratif dan dapat sedikit meringankan biaya pengobatan warga panti. Metode yang digunakan untuk memecahkan permasalahan kesehatan tersebut adalah dengan mengadakan pemeriksaan kesehatan serta memberi pengobatan. Hal ini tentu tidak terlepas dari permintaan dan kebutuhan yang diperlukan di masyarakat khususnya warga panti. Dari kegiatan pemeriksaan kesehatan gratis yang diberikan, banyak yang mengikuti terutama warga panti baik lansia maupun petugas panti, terdapat 57 orang yang sudah diberikan pemeriksaan kesehatan, baik pemeriksaan kolesterol, asam urat, maupun gula darah sewaktu, dengan hasil pemeriksaan untuk kolesterol 15,7% yang mempunyai nilai yang tidak normal, 10,52% untuk Gula darah dan 33,33% untuk asam urat. Dari pemeriksaan kesehatan yang dilakukan banyak lansia yang bisa mengikuti kegiatan, walaupun ada beberapa juga yang harus dilakukan pemeriksaan ke wisma masing-masing, karena keterbatasan lansia untuk berjalan ke aula tempat pemeriksaan kesehatan yang dilakukan.
Layanan Pusat Pangan Serba Lima Ratus (Layangan Putus): Pemberdayaan Ibu Rumah Tangga Perum Griya Satria Brebes
Authors: Rahmawati Titi , Wulandari Hilda Kumala , Purwanti Yunika 
Published: September 2022

Food processing skills are the ability of the average housewives in Griya Satria Housing. However, knowledge about the value of the Nutritional Adequacy Rate (AKG) is still low. The term of satiety on the breakfast menu is still an everyday habit. This condition influenced by the limited types and variations of breakfast menus in the environment around Perum Griya Satria. The layangan putus program aimed to increase the knowledge and appearance of environmentally friendly entrepreneurship; increase knowledge and skills in family and business financial management by utilizing applications; increase knowledge and skills in the processing of healthy breakfast foods. These activities carried out at Perum Griya Satria Brebes, Central Java. A total of 50 people were involved as participants. The form of this activity was counseling and training which was divided into two stages. The counseling method was delivered in the form of lectures and discussions while the training was carried out with food processing practices in the food laboratory. The pretest results showed an average score of 63.84 and there was an increase in the post-test score to 85.25. This showed an increase in the score of 21.41 points. Assistance and training in healthy food processing is very important for nutritional adequacy, especially in breakfast intake.

ABSTRAK
Keahlian pengolahan pangan merupakan kemampuan rata-rata ibu rumah tangga di Perumahan Griya Satria. Namun pengetahuan tentang nilai Angka Kecukupan Gizi (AKG) masih sangat rendah. Istilah yang penting kenyang pada menu sarapannya masih menjadi kebiasaan setiap hari, kondisi tersebut juga dipengaruhi oleh terbatasnya jenis dan variasi menu sarapan di lingkungan sekitar Perum Griya Satria. Program layangan putus bertujuan meningkatkan pengetahuan dan keterampilan kewirausahaan ramah lingkungan; meningkatkan pengetahuan dan keterampilan manajemen keuangan keluarga dan usaha dengan memanfaatkan aplikasi; meningkatkan pengetahuan dan keterampilan dalam pengolahan panganan sarapan yang sehat. Kegiatan abdimas dilaksanakan di Perum Griya Satria Brebes, Jawa Tengah. Sebanyak 35 orang terlibat sebagai peserta. Bentuk kegiatan ini adalah penyuluhan dan pelatihan yang terbagi dalam dua tahap. Metode penyuluhan disampaikan dalam bentuk ceramah dan diskusi sedangkan pelatihan dilakukan dengan praktik pengolahan pangan di laboratorium pangan. Hasil pre-test menunjukkan rerata skor sebanyak 63,84 dan terjadi peningkatan skor post-test menjadi 85,25. Hal tersebut menunjukkan peningkatan skor sebanyak 21,41 poin. Pendampingan dan pelatihan pengolahan panganan sehat sangat penting bagi ketercukupan gizi terutama pada asupan sarapan.
Combined analysis of finite element model and audiometry provides insights into the pathogenesis of conductive hearing loss
Authors: Hirabayashi Motoki , Kurihara Sho , Ito Ryuya , Kurashina Yuta , Motegi Masaomi , Okano Hirotaka James , Yamamoto Yutaka , Kojima Hiromi , Asakura Takumi 
Published: September 2022

The middle ear transmits sound to the inner ear via vibrations in the eardrum and ossicles, and damage to the middle ear results in conductive hearing loss. Although conductive hearing loss can be corrected by surgery, the currently available clinical investigations cannot always diagnose the ossicular chain pathology underlying the conductive hearing loss, and even intraoperative findings can be equivocal. Acoustic analysis using finite element models (FEMs) can simulate the sound pressure change at an arbitrary site for each frequency. FEMs are used in acoustic engineering to simulate the frequency-dependent sound pressure distribution at discrete cells in a simulated model and analyze the effects of specific parameters on the audiogram. However, few reports have compared the numerical results obtained using FEMs with data from clinical cases. We used FEMs to simulate audiograms of the air-bone gap (ABG) for various ossicular chain defects and compared these with preoperative audiograms obtained from 44 patients with a normal tympanic membrane who had otosclerosis, middle ear malformations or traumatic ossicular disruption. The simulated audiograms for otosclerosis and attic fixation of the malleus-incus complex both exhibited an up-slope but could be distinguished from each other based on the ABG at 1000 Hz. The simulated audiogram for incudostapedial joint discontinuity exhibited a peak at around 750 Hz and a down-slope above 1000 Hz. In general, the simulated audiograms for otosclerosis, attic fixation and incudostapedial joint discontinuity were consistent with those obtained from clinical cases. Additional simulations indicated that changes in ossicular mass had relatively small effects on ABG. Furthermore, analyses of combination pathologies suggested that the effects of one defect on ABG were added to those of the other defect. These FEM-based findings provide insights into the pathogenesis of conductive hearing loss due to otosclerosis, middle ear malformations and traumatic injury.
Evaluating the adsorption performance of functional building material with HCHO remover
Authors: Jung Chuloh , Alqassimi Nahla , El Samanoudy Gamal 
Published: September 2022

Dubai Municipality is making significant efforts to reduce the concentration of chemical substances in major buildings via Green Building Regulations &amp; Specifications. However, it has limitations to the problem because it simply regulates the indoor air concentration of some harmful substances from building materials. The functional building materials capable of adsorbing and decomposing indoor pollutants such as Formaldehyde (HCHO) and Volatile Organic Compounds (VOCs) are gradually spreading. This paper aims to evaluate the performance of functional building materials and analyze the effect of improving the indoor air environment. As a methodology, the investigation was done to research trends and standards for functional building standards. 20 L small chamber experiment was performed for wallpaper with 0%, 5%, 7%, 10%, and 15% of the ethylene urea (C5H10N2O3), HCHO remover. The result showed standard wallpaper’s adsorption rate on the seventh day was 6.21%. The formaldehyde remover adsorption rate for 7 days was 50.43% when formaldehyde remover was added at a 5 wt% (weight percentage); 60.21% when it was added at 7 wt%; 63.45% when it was added at 10 wt%; and 73.58% when it was added at 15 wt%. The adsorption rate on the seventh day with 7 wt%, 10 wt%, and 15 wt% HCHO remover showed a 60% or more (IS O 16000-24 standard). However, wallpaper with 15 wt%, displayed the highest value, was 5.736 μg/m2, which did not satisfy the IS O 16000-24 standard (6.000 μg/m2). It was statistically proven when the amount of the HCHO remover is increased; the adsorption performance is improved in proportion to the amount added. This study will serve as primary data to prepare UAE standards for the functional building materials with adsorption and decomposition performance of harmful chemicals, moisture absorption and moisture-proof performance, and antibacterial/anti-fungal performance.
Exploration of the core protein network under endometriosis symptomatology using a computational approach
Authors: El Idrissi Fatima , Fruchart Mathilde , Belarbi Karim , Lamer Antoine , Dubois-Deruy Emilie , Lemdani Mohamed , N’Guessan Assi L. , Guinhouya Benjamin C. , Zitouni Djamel 
Published: September 2022

BackgroundEndometriosis is defined by implantation and invasive growth of endometrial tissue in extra-uterine locations causing heterogeneous symptoms, and a unique clinical picture for each patient. Understanding the complex biological mechanisms underlying these symptoms and the protein networks involved may be useful for early diagnosis and identification of pharmacological targets.MethodsIn the present study, we combined three approaches (i) a text-mining analysis to perform a systematic search of proteins over existing literature, (ii) a functional enrichment analysis to identify the biological pathways in which proteins are most involved, and (iii) a protein–protein interaction (PPI) network to identify which proteins modulate the most strongly the symptomatology of endometriosis.ResultsTwo hundred seventy-eight proteins associated with endometriosis symptomatology in the scientific literature were extracted. Thirty-five proteins were selected according to degree and betweenness scores criteria. The most enriched biological pathways associated with these symptoms were (i) Interleukin-4 and Interleukin-13 signaling (p = 1.11 x 10-16), (ii) Signaling by Interleukins (p = 1.11 x 10-16), (iii) Cytokine signaling in Immune system (p = 1.11 x 10-16), and (iv) Interleukin-10 signaling (p = 5.66 x 10-15).ConclusionOur study identified some key proteins with the ability to modulate endometriosis symptomatology. Our findings indicate that both pro- and anti-inflammatory biological pathways may play important roles in the symptomatology of endometriosis. This approach represents a genuine systemic method that may complement traditional experimental studies. The current data can be used to identify promising biomarkers for early diagnosis and potential therapeutic targets.
Cardiovascular and renal burdens among patients with MAFLD and NAFLD in China
Authors: Wang Yuying , Yu Yuetian , Zhang Haojie , Chen Chi , Wan Heng , Chen Yi , Xia Fangzhen , Yu Shiyan , Wang Ningjian , Ye Lin , Lu Yingli 
Published: September 2022

Background/PurposeMetabolic associated fatty liver disease (MAFLD) was proposed as a new definition to put emphasis on the metabolic aspects of nonalcoholic fatty liver disease (NAFLD). We aim to compare the cardiovascular and renal burden between MAFLD and NAFLD patients.Methods12183 participants were enrolled in East China. The cardiovascular burden (Framingham risk score and previous cardiovascular diseases (CVD)) and renal burden (eGFR and chronic kidney disease (CKD)) were measured.ResultsThe risk of hypertension, dyslipidemia, diabetes, overweight/obesity, and central obesity of MAFLD patients were higher than those of NAFLD. Patients with MAFLD have a similar or higher beta coefficients in Framingham risk score [beta (95%CI): male 0.062 (0.055,0.069) vs 0.041 (0.033,0.048); female 0.014 (0.012,0.016) vs 0.012 (0.01,0.014)], and higher odds ratio in previous CVD [odds ratio (95%CI): male 1.50 (1.22,1.85) vs 1.35 (1.1,1.66); female 1.58 (1.33,1.87) vs 1.45 (1.22,1.72)], compared with those with NAFLD. However, compared with males with MAFLD, the odds ratio of CKD was higher in those with NAFLD [eGFR: -2.731 (-3.422, -2.041) vs-3.578 (-4.268, -2.887). CKD: 1.44 (1.05,1.96) vs 1.56 (1.14,2.12)]. In female, CKD was only marginally associated with NAFLD [0.8 (0.62,1.02), P=0.075], but not MAFLD [0.87 (0.68,1.11), P=0.268].ConclusionsPatients with MAFLD have a similar or higher risk of future and previous CVD compared with those with NAFLD, but the risk of CKD was higher in male with NAFLD.
Specific classification and new therapeutic targets for neuroendocrine prostate cancer: A patient-based, diagnostic study
Authors: Wang YouZhi , Wu Ning , Wang KeKe , Liao YiHao , Guo JiaNing , Zhong BoQiang , Guo Tao , Liang JiaMing , Jiang Ning 
Published: September 2022

Objective: Neuroendocrine prostate cancer (NEPC) is an aggressive variant of prostate cancer (PC) that may arise de novo or in patients previously treated with hormonal therapies for prostate adenocarcinoma as a mechanism of resistance. In our investigation, there appeared to be a strong correlation between neuroendocrine differentiation prostate cancer (NEDPC) and NEPC. The objectives of this study included exploring whether NEDPC is an intermediate stage in the progression of high-risk prostate cancer (HRPC) to NEPC and identifying risk factors and new targets associated with survival in the treatment of NEPC.Methods: The selected prostate cancer patients were progressed to high-risk and characterized by neuroendocrine. We collected the clinical data and characteristics of patients with three types of cancer: the incidence of metastasis, site and time of metastasis, recurrence rate, related treatment methods, etc. The similarity and differences of the three groups were compared through experiment and database.Results: By analyzing the clinical data and immunohistochemical results, we found that there seems to be a clinical feature of neuroendocrine differentiation (NED) status in between when patients progress from PC to NEPC. Finding novel treatment targets would therefore be beneficial by taking into account NEDPC as the stage of PC progression prior to NEPC. The metastasis-free survival curve and the immunohistochemical results are informing us that NEDPC can be a pre-state for diagnosing NEPC.Conclusion: NEPC is a late PC symptom that is frequently disregarded and has a bad prognosis. Finding novel treatment targets would therefore be beneficial by taking into account NEDPC as the stage of PC progression prior to NEPC.
Ultrasound radiomics features predicting the dosimetry for focused ultrasound surgery of benign breast tumor: A retrospective study
Authors: Liang Mengdi , Zhang Cai , Xia Tiansong , Chen Rui , Wang Xinyang , Weng Miaomiao , Xie Hui , Chen Lin , Liu Xiaoan , Wang Shui 
Published: September 2022

Purpose: To investigate the correlation between pre-ablation ultrasound radiomics features and the sonication energy for focused ultrasound surgery (FUS) of benign breast tumors.Method: 53 benign breast tumors of 28 patients treated by ultrasound-guided focused ultrasound surgery (USgFUS) were included in this study. The sonication energy per unit volume of each tumor was calculated. Three-quarter point was chosen as the cut-off to divide the 53 included tumors into high sonication energy (HSE, n = 14) and low sonication energy (LSE, n = 39) groups. For each tumor, the region of interest (ROI) of both the tumor itself (tROI) and the near field tissue (nfROI) were delineated and analyzed separately using ImageJ software. Pearson correlation coefficient and multiple linear regression analysis were used for radiomics feature selection. To explore the diagnostic performance of different ultrasound radiomics features, a receiver operating characteristic (ROC) curve analysis was performed.Results: In total of 68 radiomics features were extracted from pre-ablation ultrasound images of each tumor. Of all radiomics features, BX in tROI (p &lt; 0.001), BX (p = 0.001) and Circ (p = 0.019) in nfROI were independently predictive features of sonication energy per unit volume. The ROC curves showed that the area under the curve (AUC) values of BX in tROI, BX, and Circ in nfROI were 0.797, 0.787 and 0.822, respectively.Conclusion: This study provided three radiomics features of pre-ablation ultrasound image as predictors of sonication dose for FUS in benign breast tumors. Further clinical trials are needed to confirm the predictive effect of these radiomics features.