bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modelling old‐age retirement: An adaptive multi‐outcome LAD‐lasso regression approach
Authors: Lähderanta Tero , Salonen Janne , Möttönen Jyrki , Sillanpää Mikko J. 
Published: March 2022

AbstractUsing unique administrative register data, we investigate old‐age retirement under the statutory pension scheme in Finland. The analysis is based on multi‐outcome modelling of pensions and working lives together with a range of explanatory variables. An adaptive multi‐outcome LAD‐lasso regression method is applied to obtain estimates of earnings and socioeconomic factors affecting old‐age retirement and to decide which of these variables should be included in our model. The proposed statistical technique produces robust and less biased regression coefficient estimates in the context of skewed outcome distributions and an excess number of zeros in some of the explanatory variables. The results underline the importance of late life course earnings and employment to the final amount of pension and reveal differences in pension outcomes across socioeconomic groups. We conclude that adaptive LAD‐lasso regression is a promising statistical technique that could be usefully employed in studying various topics in the pension industry.
Sarcopenia is associated with the Geriatric Nutritional Risk Index in elderly patients with poorly controlled type 2 diabetes mellitus
Authors: Matsuura Shun , Shibazaki Koji , Uchida Reiko , Imai Yukiko , Mukoyama Takuya , Shibata Shoko , Morita Hiroshi 
Published: March 2022

ABSTRACTAims/IntroductionDiabetes and sarcopenia have a two‐way relationship with each other with advanced age. Additionally, malnutrition is correlated with a higher risk of sarcopenia in elderly patients. This study evaluated the association between sarcopenia and geriatric nutritional risk index (GNRI) in elderly patients with type 2 diabetes mellitus.Materials and MethodsPatients with type 2 diabetes mellitus aged ≥60 years were recruited from June 2018 to August 2020. This study analyzed 234 patients, who completed a physical performance test required for the diagnosis of sarcopenia. To investigate the effect of GNRI on sarcopenia, logistic regression analyses was used.ResultsPatients with sarcopenia were significantly older with a lower body mass index (BMI) and GNRI compared with normal patients. The GNRI showed a positive correlation with the skeletal muscle index (SMI) and handgrip strength (SMI: R = 0.486, P < 0.001 for male; R = 0.589, P < 0.001 for female, handgrip strength: R = 0.470, P < 0.001 for male, R = 0.364, P < 0.001 for female). In the multivariate logistic regression model, a higher GNRI was associated with a lower risk of sarcopenia in older men and women with diabetes (adjusted odds ratio [OR], 0.892; 95% confidence interval [CI], 0.839–0.948 for male; adjusted OR, 0.928; 95% CI, 0.876–0.982 for female). One year of diabetes treatment improved the GNRI in the sarcopenia group with type 2 diabetes mellitus.ConclusionsA low GNRI was associated with an increased risk of sarcopenia in elderly patients with type 2 diabetes mellitus. Treatment with glucose‐lowering drugs improved the GNRI in the sarcopenia group.
Thematic analysis of therapists' experiences integrating EMDR and EFT in couple therapy: Theoretical and clinical complementarity, and benefits to client couples
Authors: Linder Jason N. , Niño Alba , Negash Sesen , Espinoza Sandra 
Published: March 2022

AbstractIn this article, we present partial findings from a thematic analysis study that examined integrating emotionally focused therapy (EFT) and eye‐movement desensitization and reprocessing (EMDR) as clinical frameworks in couple therapy. The purpose of the study is to better understand how therapists integrate EFT and EMDR therapy in their clinical work. Thirteen licensed therapists (n = 13) trained in EFT and EMDR were interviewed about their experiences integrating these two models in their couple therapy practice. The findings included in this article are related to how these models complement each other as well as the clinical benefits associated with their integration. Findings provide preliminary evidence that there are benefits and challenges when integrating both models, although we emphasize complementarity in this article. Limitations and implications for future research on the integration and efficacy of these two models are also discussed.
The future of divorce support: Is “digital” enough in presence of conflict?
Authors: Ciprić Ana , Hald Gert Martin , Strizzi Jenna Marie , Lange Theis , Austin David , Sander Søren , Øverup Camilla Stine 
Published: March 2022

AbstractDivorce conflict is the main driver of adverse postdivorce health adjustments among divorcing families. Despite the growing potential of online divorce support programs, there is concern that such solutions might not be sufficient to impact health‐related disparities among high‐conflict divorcees. The present study examined the effectiveness of the digital “Cooperation after Divorce” intervention as a function of conflict among 1856 recently divorced Danish residents. Linear mixed‐effect regression modeling suggested that, although higher levels of divorce conflict at judicial divorce predicted worse health outcomes up to 1 year following divorce, the effectiveness of the digital divorce intervention did not vary as a function of the initial level of divorce conflict. Individuals in the intervention group with higher conflict in divorce still reported worse health at 12 months follow‐up than those with lower levels of divorce conflict; however, much lower than the control group.
Simple automation of SEM‐EDS spectral maps analysis with Python and the edxia framework
Authors: Georget Fabien , Wilson William , Scrivener Karen L. 
Published: March 2022

AbstractIn a recent article, we described the edxia framework, a user‐friendly framework to analyse the microstructure of cementitious materials using SEM‐EDS hypermaps. The manual approach presented was shown to be efficient to answer the relevant scientific questions. However, it is limited for batch analysis and (semi‐)automated treatments. In this article, we show how the framework can be used to customise the analysis to the problem at hand. We first present some possible extensions, and then we provide a simple example of automatic clustering, using the flexible Python scientific libraries which will allow to define more custom workflows in the future.
More money, more problems? An examination of the dynamic relationship between income and work–family conflict
Authors: Rubenstein Alex L. , Morrison Hayley M. , Whiting Steven W. , Bosco Frank A. 
Published: March 2022

Income from regular employment is a primary means by which individuals support themselves. Yet, little research has examined how making more money over time relates to employees’ ability to simultaneously manage work and family role obligations. Drawing from resource allocation theory, in two studies we examined the dynamic relationship between income and work–family conflict (WFC). We hypothesized that income trends would positively predict WFC trends, as making more money could demand employees devote greater resources to their work role, depleting remaining resources to devote to family. In Study 1, with data from a large sample surveyed over 4 years, we found that income trends were positively associated with WFC trends. Further, this relationship was more accentuated for women than men. In Study 2, we sought to replicate and extend the Study 1 findings by modelling theoretical mechanisms that could account for the positive dynamic income–WFC relationship. We again found a positive relationship, although the income–gender interaction failed to replicate. Mediation analyses revealed increased investments of the self into work explained the link between increased income and increased WFC, compared to other mechanisms. As a whole, in terms of WFC, more money earned ultimately conferred more, not less, problems for employees.Practitioner points

Our findings suggest that income changes over time positively predict work–family conflict changes over time. Although pay is of course a significant motivator of desired work behaviour, our results highlight some of the peripheral consequences that might result as employees make more money.

Our research suggests this dynamic relationship is best explained by employees’ increased investments of the self into work, and therefore concerns a need for well‐paid employees to think more about how they balance work and family goals.

In one of two samples, the positive income–WFC dynamic relationship was stronger for women than for men, highlighting not only that making more money can increase WFC over time but also for whom it is more likely to do so.
Identification, biological characteristics and fungicide sensitivity of Colletotrichum species that cause anthracnose on Anemarrhena asphodeloides in China
Authors: Wei Ruofan , Wang Rong , Li Yong , Yue Moyi , Ding Wanlong 
Published: March 2022

AbstractZhi mu (Anemarrhena asphodeloides Bunge.) is an important medicinal plant in China, and its growth is greatly threatened by the fungal disease anthracnose, which can be caused by a number of species of Colletotrichum. Studying the phytopathogen and its sensitivities to fungicides will help to control anthracnose on zhi mu. Ten isolates of Colletotrichum were collected from zhi mu in Hebei, Anhui and Shanxi Provinces in China for this study. The isolates were identified as C. gloeosporioides, C. liriopes and C. spaethianum based on multi‐locus phylogenetic analyses, including ACT, CHS‐1, GADPH, HIS3 and ITS, micromorphological characteristics and the characteristics of colonies. Koch's postulates were confirmed by inoculating the leaves of zhi mu in vitro. The levels of virulence of 10 isolates varied significantly. Isolate YC‐1 was the most virulent, while BZ‐2 was the least virulent. The sensitivity of isolates YC‐1, BY‐1 and BY‐2 (C. spaethianum, C. gloeosporioides and C. liriopes respectively) to fungicides were examined. The EC50 values of BY‐1, BY‐2, and YC‐1 to tebuconazole, difenoconazole, prochloraz, fludioxonil, pyraclostrobin, carbendazim and azoxystrobin confirm that all of the isolates were markedly sensitive to the seven fungicides tested, strongly suggesting that these fungicides could be used to control anthracnose on zhi mu in the field.
Development of the Japanese Version of the Short Scale of Creative Self1, 2
Authors: Ishiguro Chiaki , Matsumoto Kazuki , Agata Takumitsu , Okada Takeshi 
Published: March 2022

AbstractThis study aimed to translate the Short Scale of Creative Self (SSCS) into Japanese and examine its psychometric properties. In total, 1,436 participants (Study 1: N = 957, Study 2: N = 479) completed the questionnaires. In Study 1, confirmatory factor analyses for Japanese versions of the scales resulted in bi‐factor structures comprising one general factor and two subfactors; namely, creative self‐efficacy (CSE) and creative personal identity (CPI). However, the Japanese version of the SSCS (SSCS‐J) was essentially unidimensional, and scoring based on CSE and CPI lacked support. Therefore, it was necessary to calculate the total SSCS‐J item scores to measure the creative self. Study 2 provided evidence for the concurrent, convergent, and discriminant validity of the scale. The current study also found that the SSCS‐J had adequate test–retest reliability. The present findings suggest that the SSCS‐J has sufficient reliability and validity.
Spindle‐targeted acoustic stimulation may stabilize an ongoing nap
Authors: Choi Jinyoung , Jun Sung Chan 
Published: March 2022

SummaryThere have been numerous attempts over the decades to introduce closed‐loop feedback to induce sleep oscillations. Recently, our group also introduced closed‐loop acoustic feedback to the sleep spindle and reported improved procedural memory consolidation during a nap with spindle‐targeted pink noise stimulation. In this study, we replicated our previous work with a control condition in an attempt to investigate the effect of closed‐loop feedback on procedural memory. The results demonstrated a significant improvement in the subjects’ procedural learning and reduced wake time during the nap with closed‐loop acoustic stimulation compared with the control condition. Further, we found that randomized acoustic stimuli lead to more frequent spindle activity and a faster decrement in slow oscillation power compared with the sham condition. There were strong correlations between slow oscillation and measures related to sleep efficiency as well. Interestingly, we found a marginal enhancement in procedural learning during the nap with the closed‐loop acoustic stimulation compared with the sham nap. We also found a marginal decrement in theta power during the nap with closed‐loop feedback compared with the sham nap, and a negative correlation between slow oscillation and theta power. We speculate that the marginal improvement in procedural learning may be related to closed‐loop acoustic feedback’s stabilization of non‐rapid eye movement sleep. Taken together, this study shows that the closed‐loop feedback method has the potential to stabilize sleep and improve procedural memory.
Trichoderma harzianum antagonistic activity and competition for seed colonization against seedborne pathogenic fungi of sunflower
Authors: Güçlü T. , Özer N. 
Published: March 2022

Abstract
This study investigated the antagonistic effects of Trichoderma harzianum isolate (TRIC8) on mycelial growth, hyphal alteration, conidial germination, germ tube length and seed colonization by the seedborne fungal pathogens Alternaria alternata, Bipolaris cynodontis, Fusarium culmorum and F. oxysporum, the causes of seedling rot in over 30% of sunflowers. The antagonistic effect of TRIC8 on mycelial growth of pathogens was evaluated on dual culture that included two inoculation assays: inoculation of antagonist at 48 h before pathogen (deferred inoculation) and inoculation at the same time with pathogen (simultaneous inoculation). TRIC8 inhibited mycelial growth of the fungal pathogens between 70·67 and 76·87% with the strongest inhibition seen with deferred inoculation. Alterations in hyphae were observed in all pathogens. Conidial germination of F. culmorum was inhibited by most of the fungal pathogens (38·28%) by TRIC8. Inhibition of germ tube length by the antagonist varied from 31·83 to 37·67%. In seed colonization experiments, TRIC8 was applied in combination with each pathogen to seeds of a sunflower genotype that is highly tolerant to downy mildew. Seed death was inhibited by TRIC8 and the antagonist did not allow growth of A. alternata, B. cynodontis and F. culmorum on seeds and inhibited the growth of F. oxysporum at the rate of 58·32%.
The Payer License Agreement, or “Netflix model,” for hepatitis C virus therapies enables universal treatment access, lowers costs and incentivizes innovation and competition
Authors: Matthews David W. , Coleman Samantha , Razavi Homie , Izaret Jean‐Manuel 
Published: March 2022

AbstractBackground and AimsHigh unit prices of treatments limit access. For epidemics like that of hepatitis C virus (HCV), reduced treatment access increases prevalence and incidence, making the infectious disease increasingly difficult to manage. The objective of the current study was to construct and test an alternative pricing model, the Payer License Agreement (PLA), and determine whether it could improve outcomes, cut costs and incentivize innovation versus the current unit‐based pricing model.MethodsWe built and used computational models of hepatitis C disease progression, treatment, and pricing in historical and future scenarios and quantitatively analyzed their economic and epidemiological impact in three high‐income countries.ResultsThis study had three key results regarding HCV treatment. First, if the PLA model had been implemented when interferon‐free direct‐acting antiviral (DAA) combinations launched, the number of patients treated and cured would have more than doubled in the first three years, while the liver‐related deaths (LRDs) would have decreased by around 40%. Second, if the PLA model had been implemented beginning in 2018, the year that several Netflix‐like payment models were under implementation, the number of treated and cured patients would nearly double, and the LRDs would decline by more than 55%. Third, implementing the PLA model would result in a decline in total payer costs of more than 25%, with an increase to pharmaceutical manufacturer revenues of 10%. These results were true across the three healthcare landscapes studied, the USA, the UK and Italy, and were robust against variations to critical model parameters through sensitivity analysis.Conclusions and RelevanceThese results suggest that implementation of the PLA model in high‐income countries across a variety of health system contexts would improve patient outcomes at lower payer cost with more stable revenue for pharmaceutical manufacturers. Health policy‐makers in high‐income countries should consider the PLA model for application to more cost‐effective management of HCV, and explore its application for other infectious diseases with curative therapies available now or soon.
As the virus sowed, the fungus reaped! A comparative analysis of the clinico‐epidemiological characteristics of rhino‐orbital mucormycosis before and during COVID‐19 pandemic
Authors: Muraleedharan Manjul , Panda Naresh Kumar , Angrish Prerna , Arora Kanika , Patro Sourabha Kumar , Bansal Sandeep , Chakrabarti Arunaloke , Rudramurthy Shivaprakash Mandya , Bakshi Jaimanti , Mohindra Satyawati , Gupta Rijuneeta , Virk Ramandeep Singh , Verma Roshan Kumar , Ramavat Anurag Snehi , Nayak Gyanaranjan 
Published: March 2022

AbstractBackgroundThe sudden surge of mucormycosis cases which happened during the second wave of COVID‐19 pandemic was a significant public health problem in India.ObjectivesThe aim of this study was to analyse the clinico‐epidemicological characteristics of the mucormycosis cases to determine the changes that had occurred due to COVID‐19 pandemic.MethodologyA retrospective cross‐sectional study was conducted at the Department of Otolaryngology Head and Neck Surgery, PGIMER, Chandigarh, India. Patients diagnosed with rhino‐orbital mucormycosis were categorised into the following groups: Pre‐pandemic(May 2019 to April 2020), Pandemic Pre‐epidemic (May 2020 to April 2021) and Epidemic (1 May 2021 to 12 July 2021). The epidemiological, clinical and surgical data of all the patients were retrieved from the hospital records and analysed.ResultsThe epidemic period had 370 cases, compared with 65 during pandemic period and 42 in the pre‐pandemic period. Diabetes mellitus was seen in 87% of cases during epidemic period, 92.9% in the pre‐pandemic period and 90.8% in the pre‐pandemic pre‐epidemic period. The proportion of patients suffering from vision loss, restricted extra‐ocular movements, palatal ulcer and nasal obstruction was higher in the pre‐epidemic groups, and the difference was significant (p, <.01). There was no history of oxygen use in 85.9% of patients and no steroid use in 76.5%. The death rates were the lowest during epidemic (10%).ConclusionCOVID‐19 has caused a statistically significant increase in the number of mucormycosis infections. The mortality and morbidity which showed an increase during the first wave of COVID‐19 decreased significantly during the epidemic period.
Differential environmental and genomic architectures shape the natural diversity for trichome patterning and morphology in different Arabidopsis organs
Authors: Arteaga Noelia , Méndez‐Vigo Belén , Fuster‐Pons Alberto , Savic Marija , Murillo‐Sánchez Alba , Picó F. Xavier , Alonso‐Blanco Carlos 
Published: March 2022

AbstractDespite the adaptive and taxonomic relevance of the natural diversity for trichome patterning and morphology, the molecular and evolutionary mechanisms underlying these traits remain mostly unknown, particularly in organs other than leaves. In this study, we address the ecological, genetic and molecular bases of the natural variation for trichome patterning and branching in multiple organs of Arabidopsis (Arabidopsis thaliana). To this end, we characterized a collection of 191 accessions and carried out environmental and genome‐wide association (GWA) analyses. Trichome amount in different organs correlated negatively with precipitation in distinct seasons, thus suggesting a precise fit between trichome patterning and climate throughout the Arabidopsis life cycle. In addition, GWA analyses showed small overlapping between the genes associated with different organs, indicating partly independent genetic bases for vegetative and reproductive phases. These analyses identified a complex locus on chromosome 2, where two adjacent MYB genes (ETC2 and TCL1) displayed differential effects on trichome patterning in several organs. Furthermore, analyses of transgenic lines carrying different natural alleles demonstrated that TCL1 accounts for the variation for trichome patterning in all organs, and for stem trichome branching. By contrast, two other MYB genes (TRY and GL1), mainly showed effects on trichome patterning or branching, respectively.
A study about return policies in the presence of consumer social learning
Authors: Liu Bingsheng , Zhu Wenwen , Shen Yinghua , Chen Yuan , Wang Tao , Chen Fengwen , Liu Maggie Wenjing , Zhou Shi‐Hao 
Published: March 2022

Sellers are conventionally generous with their return policies for valuation‐uncertain products, such as experience products and new products. However, with the development of online review platforms, an increasing number of consumers are engaging in social learning by referring to others' reviews to reduce valuation uncertainty. In this study, we investigate how social learning interacts with sellers' return policies. There are three main conclusions. First, when sellers have a relatively higher expectation of product quality (or simply the product quality is high), social learning makes the sellers offering either no‐refund policies or partial‐refund policies better off in terms of the increased profit. It will cause the no‐refund sellers to choose higher prices and inventory, and the partial‐refund sellers to set lower prices and refund amounts. Second, under social learning, the partial‐refund policy tends to be more beneficial to sellers than both full‐refund and no‐refund policies; although, when the product quality is high, the no‐refund policy tends to bring more benefits to sellers than the full‐refund policy. Hence, sellers may finally switch to the partial‐refund policy. Third, for partial‐refund policies, more often than not, social learning increases social welfare when the product quality is high; specifically, in many cases, it increases not only the profit of the seller but also the welfare of consumers.
Microfinance competition and multiple borrowing: Evidence using panel data from Bangladesh
Authors: Mahmud Minhaj , Sawada Yasuyuki , Tanaka Mari 
Published: March 2022

AbstractWe examine the causes and consequences of multiple borrowing in rural Bangladesh using long‐term household and village panel data covering the years 2000–2014. We find that the sharply growing number of microfinance institutions (MFIs) in a wider set of villages over time coincides with a corresponding increase in household borrowing from multiple MFIs and households accessing loans generally as well as significant rises in the total values of household assets, especially in the form of agricultural equipment. Although the increasing number of MFIs resulted in some households borrowing to repay previous loans, the fraction of such households is relatively small.