bluuebunny/crossref_metadata_2025_split huggingface dataset:
LUNTURNYA SEKTOR PERTANIAN DI PERKOTAAN
Authors: Gultom Ferdi , Harianto Sugeng 
Published: February 2022

<p><em>The agricultural sector is an important sector for food security in Indonesia. However, the government only focused on development through the industrial sector, that agriculture faded away due to the entry of the modern sector through the central state-satellite relationship. This can be seen in the increasingly widespread conversion of agricultural land in urban areas. This study aims to describe how the decline of the agricultural sector in urban areas. This research uses a literature study approach. Data is obtained from news sources, to journals that explain the development of the industrial sector that shifts agricultural land. The data were analyzed using the Miles and Huberman model. The data are classified according to the problem formulation, then reduced to an understandable conclusion. This study uses dependency theory to help analyze the data. Dependency theory was chosen because it can explain the underdevelopment of satellite countries due to the modern sector. The results of this study indicate that the agricultural sector in urban areas is fading, due to the decrease in agricultural land, due to the widespread conversion of land for industry, infrastructure, and settlements. The regeneration of farmers has decreased, due to the lack of interest in becoming a farmer.</em></p><p><strong><em>Keywords: Agricultural Sector, Urban, Addiction, Fade</em></strong><em></em></p><p><em> </em></p><h2>Abstrak</h2><p>Sektor pertanian merupakan sektor penting untuk ketahanan pangan di Indonesia. Namun demikian, pemerintah hanya berfokus pada pembangunan melalui sektor industri, sehingga pertanian luntur akibat masuknya sektor modern melalui hubungan negara pusat-satelit. Hal tersebut terlihat alih fungsi lahan pertanian yang sering terjadi di perkotaan. Penelitian ini bertujuan menggambarkan bagaimana lunturnya sektor pertanian di perkotaan. Penelitian ini menggunakan pendekatan studi kepustakaan. Data didapatkan melalui sumber berita, hingga jurnal yang menjelaskan pembangunan sektor industri yang menggeser lahan pertanian. Analisis data menggunakan menggunakan Model Miles dan Huberman. Data diklasifikasikan sesuai dengan rumusan masalah, kemudian direduksi menjadi kesimpulan yang dapat dipahami. Penelitian ini menggunakan teori ketergantungan untuk membantu menganalisis data. Teori ketergantungan dipilih sebab dapat menjelaskan keterbelakangan negara satelit dikarenakan sektor modern. Hasil penelitian ini menunjukan bahwa sektor pertanian di perkotaan semakin luntur, karena lahan pertanian yang semakin berkurang, karena maraknya alih fungsi lahan untuk industri, infrasturkur, dan pemukiman. Regenerasi petani menurun, akibat tidak ada minat menjadi petani.</p><p><strong>Kata Kunci: Sektor Pertanian, Perkotaan, Ketergantungan, Luntur</strong></p>
Evaluation of a Pre-clinic Diabetes Assessment and Mapped Care Planning Intervention: a Multi-Centre Randomised Controlled Trial
Authors: Barnard-Kelly Katharine Katharine , Kelly Ryan Charles , Phiri Peter , Price Hermione , Ali Amar , Stratton Irene , Austin Kayleigh , Neave Alice 
Published: February 2022

Abstract
Introduction: Existing therapeutic interventions to treat diabetes are well known, yet the majority of people with diabetes do not consistently achieve blood glucose targets (even individual therapy targets) for optimal health, despite the large range of treatment options available. Such outcomes have remained stubbornly poor for decades with <25% adults with diabetes achieving glycaemic targets. Patient behaviour, individually supported in routine clinical care, is an important missing component to improved outcomes, in a medical healthcare model not ideally suited to supporting successful diabetes management. Participants: Adults with type 1, type 2 or pre-diabetes attending routine care outpatient appointments.Design: A multi-centre, parallel group, individually randomised trial comparing consultation duration in adults with type 1, type 2 or pre-diabetes using the Spotlight Consultations pre-clinic assessment compared to usual care in the Spotlight-AQ study.Intervention: An outpatient pre-clinic intervention delivered within one week prior to scheduled routine outpatient appointment.Sample size: 200 recruited across up to 10 sites.Primary outcome measure: Duration of routine outpatient consultation.Secondary outcome measures:· Functional health status· diabetes distress · depression· treatment satisfaction· impact on self-care behaviours· HCP burnout· HCP treatment satisfaction and burden · hypoglycaemia (time less than 70mg/dL)· hyperglycaemia (time above 180 mg/dL)· Change in weight · Change in HbA1c · Cost effectiveness of interventionEthics and dissemination: The trial was approved by the Wales REC7 Research Ethics Committee (21/WA/0020). Results will be disseminated through national and international conferences, scientific journals, newsletters, magazines and social media. Target audiences include consultants and other clinicians in diabetes, and medical professionals or scientists overall. Trial Registration: ISRCTN15511689
Factors Influencing the Elderly's Adoption of mHealth: An Empirical Study Using Extended UTAUT2 Model
Authors: Palas Jahir , Sorwar Golam , Hoque Md. , Sivabalan Achchuthan 
Published: February 2022

Abstract
Background: mHealth (mobile health) has a far-reaching impact on delivering health services to a low-resource and remote population, especially elderlies with regular and emergency health needs in developing nations. Even though the high usage of mobile phones in daily life in developing countries like Bangladesh, adoption, and usage of mHealth services have been significantly low among the elderly population. Hence, this study aimed to identify key factors that influence elderlies’ intention to adopt and use mHealth services by extending the Unified Theory of Acceptance and Use of Technology (UTAUT2) model.Methods: A face-to-face structured questionnaire survey method was used to collect data from 493 elderlies (aged 60 years and above) in Bangladesh. The data were analyzed with the Structural Equations Modelling (SEM) and Fuzzy Set Qualitative Comparative Analysis (fsQCA).Results: SEM results suggested that Social Influence, Hedonic Motivation, Price Value, Habit, and Service Quality had significant impact (p<0.05) on the elderlies’ behavioral intention to adopt mHealth services. Service Quality, Quality of Life, and elderlies’ Habit were found significant in explaining the Use Behavior of mHealth services. Quality of Life did not show significant (p>0.05) effect on Behavioral Intention which is inconsistent with existing literature. In addition, fsQCA findings suggest how the intensity of the influencers may contribute to high vs low m-health behavioral outcomes.Conclusions: The findings have significant implications for theory, practice and future research as explained in the concluding section of the paper. The extension of UTUAT2 in this study would contribute in the literature of mHealth especially considering the fact that elderlies' quality of life is an important determinant of the continued mHealth use behavior. Overall, the findings may contribute to shaping appropriate policies for designing and implementing mHealth services effectively for elderlies in developing countries.
A predictive model for recurrence after upfront surgery in patients with resectable pancreatic ductal adenocarcinoma (PDAC) by using preoperative clinical data and CT characteristics
Authors: Tian Ningzi , Wu Dong , Zhu Lei , Zeng Mengsu , Li Jianke , Wang Xiaolin 
Published: February 2022

Abstract
Background

The purpose of this study was to develop and validate a predictive model to assess recurrence survival risk in patients with PDAC after upfront surgery by using preoperative clinical data and CT characteristics.
Methods

The predictive model was developed based on a retrospective set of 141 pancreatic cancer patients after surgery. A separate set of 77 patients was used to validate model. Between January 2017 and December 2019, all patients underwent multidetector pancreatic CT and upfront surgery. Univariable and multivariate Cox regression was used to determine the risk factors related to recurrence and then establish a nomogram to estimate the 1-year recurrence probability. Area under curve (AUC) and calibration curve are employed in evaluating the discrimination and calibration of the model.
Results

A total of 218 patients in this retrospective cohort. A recurrence model in nomogram form was developed with predictors including tumor size, tumor density in the portal vein phase, peripancreatic infiltration, suspicious metastatic lymph node, and Neutrophils/Lymphocytes ratio (109/L). The predictive nomogram had good discrimination capability with these predictors achieved an area under the curve for 1 year of 84.2(95%CI: 77.2, 91.2) in the development set and 0.82(95% CI: 0.72, 0.92) and 0.84 (95% CI: 0.74, 0.94) in the validation set for two radiologists reading respectively.
Conclusions

The model developed based on preoperative clinical data and CT characteristics of resectable pancreatic ductal adenocarcinoma patients, which can helpfully estimate the recurrence-free survival (RFS). It may be a useful tool for clinician to select optimal candidates for upfront surgery or neoadjuvant therapy.
Bayesian Parametric Modeling of Time to Tuberculosis Co-infection of HIV/AIDS Patients Under Antiretroviral Therapy Treatment at Jimma University Medical Center, Ethiopia
Authors: Umeta Abdi Kenesa , Yermosa Samuel Fikadu , Dufera Abdisa G. 
Published: February 2022

Abstract
Background: Tuberculosis is the most common opportunistic infection among HIV/AIDS patients, including those following Antiretroviral Therapy treatment. The risk of Tuberculosis infection is higher in people living with HIV/AIDS than in people who are free from HIV/AIDS. Many studies focused on prevalence and determinants of Tuberculosis in HIV/AIDS patients without taking into account the censoring aspects of the time to event data. Therefore, this study was undertaken with aim to model time to Tuberculosis co-infection of HIV/AIDS patients following Antiretroviral Therapy treatment using Bayesian parametric survival models. Methods: A data of a retrospective cohort of HIV/AIDS patients under Antiretroviral Therapy treatment follow-up from January 2016 to December 2020 until Tuberculosis was clinically diagnosed or until the end of the study was collected from Antiretroviral Therapy treatment center of Jimma University Medical Center, Ethiopia. In order to identify the risk factors which have association with Tuberculosis co-infection survival time, Bayesian parametric Accelerated failure time survival models were fitted to the data using Integrated Nested Laplace Approximation methodology. Results: About 26.37% of the study subjects had been co-infected with tuberculosis during the study period. Among the parametric Accelerated failure time models, the Bayesian log-logistic Accelerated failure time model was found to be the best fitting model for the data. Conclusions: Tuberculosis co-infection survival time was significantly associated with place of residence, smoking, drinking alcohol, family size, WHO clinical stages, functional status, CD4 count, BMI and hemoglobin level. The finding of this study provide timely information on the risk factors associated with TB co-infection survival time for healthy policy makers and planners.
Diagnostic Accuracy of Cardiac Computed Tomographic Angiography and Transesophageal Echocardiography in Evaluation of Patients with Prosthetic Paravalvular Leakage
Authors: Youssef Amr , Kassem Hussien Heshmat , Salem Mohamed Ali , Kandil Hossam Ibrahim 
Published: February 2022

Abstract
Introduction and purpose:
Computed Tomography (CT) scan has been well addressed to provide a diagnostic information for patients with prosthetic heart valve dysfunction. However, its role in the assessment of patients with prosthetic paravalvular leakage (PVL) has not been studied thoroughly. So, this study was conducted to assess the feasibility, reproducibility, and accuracy of CT for diagnosis of prosthetic PVL using surgical findings as the reference standard.
Methods and results:
This was a prospective cohort study that was conducted on 26 consecutive patients with suspected prosthetic PVL who underwent both transesophageal echocardiography (TEE) and 64-slice ECG-gated CT. The gold standard was the intraoperative findings. Surgery was performed in twenty-six patients. There was an excellent degree of agreement between CT and intraoperative findings for diagnosis, localization of prosthetic PVL. The perimeter of prosthetic PVL measured by CT was strongly correlated with echocardiographic severity of PVL by TEE (Spearman’s Correlation Coefficient, r = 0.83, P value = 0.0014).
Conclusion
This study demonstrates that cardiac CT showed comparable diagnostic accuracy to TEE and intraoperative findings for the detection, localization, and assessment of severity of prosthetic PVL. Moreover, CT was shown to be useful in detection of other findings related to prosthetic cardiac valves.
OXR1 Signaling Pathway as a Possible Mechanism of Elastase-Induced Oxidative Damage in Pulmonary Cells: The Protective Role of Ellagic Acid
Authors: Bayati Vahid , Radan Maryam , Dianat Mahin , Mansouri Zahra , Souhrabi Farzaneh 
Published: February 2022

Abstract
Background and objective: Oxidative stress is a process that occurs through free radicals on the cell membranes which causes damage to the cell and intracellular organelles especially mitochondria membranes. H2O2 induced oxidative stress in human cells is of interest in toxicological research since oxidative stress plays a main role in the etiology of several pathological conditions. Neutrophil Elastase (Serine proteinase) is involved in the pathology process of emphysema as a respiratory disease through lung inflammation, and destruction of alveolar walls. The present study investigated the direct oxidative stress effects of Elastase in comparison with H2O2 on human lung epithelial cells (A549 cells) in relation to the generation of reactive oxygen species (ROS) and modulation of oxidation resistance 1 (OXR1) and its downstream pathway using the well-known antioxidant Ellagic acid as an activator of antioxidant genes. Materials and methods: The human pulmonary epithelial cells (A549) were divided into the 9 groups including: Negative control, Positive control (H2O2), Elastase (15, 30, and 60 mU/ml), Ellagic acid (10 μmol/L), and Elastase+Ellagic acid. Cytotoxicity, reactive oxygen spices generation, oxidative stress profile, level of reactive metabolites, and gene expression of OXR1 and its downstream genes were measured in all groups. Results: The obtained data demonstrated that Elastase exposure caused to oxidative stress damage in a dose-depended manner which was associated with decreases in antioxidant defense system genes. Conversely, treatment with Ellagic acid as a potent antioxidant showed improved antioxidant enzyme activity and content which was in line with the upregulation of OXR1 signaling pathway genes. Conclusions: The present findings can highlight the novel mechanism underlying the oxidative stress induces by Neutrophil Elastase through OXR1 and related genes. Moreover, the benefit of Ellagic acid on cytoprotection, resulting from its antioxidant properties was documented.
Dental Students’ Emotions, Knowledge, Awareness And Learning Intention On The Applications of Nanotechnology In Dentistry
Authors: Senocak Erdal , Sarıkaya Işıl , Hatırlı Hüseyin , Coşgun Alem 
Published: February 2022

Abstract
Background: Dentistry includes vast applications of nanotechnology from preventive dentistry to diagnostics. However, we have limited knowledge about dentistry students’ perceptions of the emerging applications of nanotechnology in dentistry. This study aims to reveal a group of dental students’ knowledge, emotions, awareness and learning intentions on the emerging applications of nanotechnology in dentistry. Methods: This study was carried out through a quantitative research design. A questionnaire including four parts was administered to a total of 269 dental students from different grade levels. Data were summarized using descriptive statistics and the chi-square test. All statistical analysis were done by using the SPSS Version 22.Results: Findings of the dataset indicated that most of the participants had heard some or a lot about nanotechnology. Also, they displayed positive emotions toward nanotechnology. Almost 60% of participants stated that they know what nanotechnology means, whereas more than 70% of them reported that they don’t know how nanotechnology works. Findings also showed that as the grade level increased, more students became aware of the applications of nanotechnology. In addition, the participants thought that they needed to get more information about the applications of nanotechnology in dentistry education and in future dental practices.Conclusion: The results of the study revealed that dental students were familiar with nanotechnology and displayed positive emotions towards nanotechnology. Also they desired to learn more information about the applications of nanotechnology. In addition, findings showed that as the grade level increased, more students became aware of the applications of nanotechnology.
Functional and Morphologic Dysfunctions on Airways of Rats Submitted to an Experimental Model of Obesity-exacerbated Asthma
Authors: Ferreira Sarah Rebeca Dantas , Pessoa Rayane Fernandes , Figueiredo Indyra Alencar Duarte , Lima João Pedro Moura , Moura Thayna Maria Costa Fernandes , Bezerra Cleyton Oliveira , Martins Alissa Maria Oliveira , Carvalho Leila Moreira , Madruga Marta Suely , Cavalcante Hassler Clementino , Aquino Jailane Souza , Alves José Luiz Brito , Alves Adriano Francisco , Vasconcelos Luiz Henrique César , Cavalcante Fabiana Andrade 
Published: February 2022

Abstract
Obesity-exacerbated asthma phenotype is characterized by more severe asthma symptoms and glucocorticoid resistance. The aimed of this study is to standardize an obesity-exacerbated asthma model by high glycemic level index (HGLI) diet and ovalbumin (OVA) sensitization and challenges in Wistar rats. Animals were divided into groups: control (CG), obese (OG), asthmatic (AG), obese asthmatic (OAG) and obese asthmatic treated with dexamethasone (OADEXAG) and in vivo and in vitro functional and morphological parameters were measured. After HGLI consumption there was an increase in body weight, abdominal circumferences, body mass index, retroperitoneal, epididymal, inguinal adipose tissues and adiposity index. Respiratory function showed reduction in pulmonary tidal and minute-volume. In isolated trachea, the cumulative concentration-response curves for carbachol showed increase in contractile efficacy in OG, AG, OAG and OADEXAG, while OAG showed the greatest contractile efficacy. Histological sections of lungs showed an increased peribronchovascular inflammatory area on OAG, smooth muscle hypertrophy and remodeling area filled by extracellular matrix, and these changes were not reversed by treatment with dexamethasone. Obesity-exacerbated asthma model was successfully established. Therefore, this model allows further molecular investigations and the search for new therapeutic alternatives for the treatment and relief of symptoms of patients of obesity-induced resistant asthma.
Effect of TiC0.4 Addition on Microstructures and Properties of Ti3SiC2 Matrix Composites
Authors: Zou Qin , Lou Zhichao , Liu Junlong , Li YanGuo , Xu Jiangbo , Li Yuanyuan , Bu Lingyu , Wang Peng , Luo Yong’an 
Published: February 2022

Abstract
TiC0.4-Ti3SiC2 composites were manufactured using spark plasma sintering (SPS) at 1400°C for 10 min, with an applied pressure of 40 MPa. The effect of TiC0.4 additions on microstructures and properties of Ti3SiC2 matrix composites was investigated. The addition of TiC0.4 induced the formation of TiCx (0.4༜x≤1) and promoted the decomposition of Ti3SiC2, yielding TiCx and Ti5Si3. The mechanical and tribological properties of the TiC0.4-Ti3SiC2 composite improved with the TiC0.4 content due to C vacancy present in TiC0.4, although the friction distance in the initial stage of friction test was increased. The 30 vol.% TiC0.4-Ti3SiC2 composites exhibited the highest hardness and fracture toughness of 14.87 GPa and 5.45 MPa⋅m1/2. At the same conditions, the wear rate at room temperature reached a minimum value of 4.32×10−7mm3N−1m−1, while the friction coefficient was 0.74. The friction distance in the initial friction stage of 30 vol.% TiC0.4-Ti3SiC2 was about 38 m, and the wear mechanism of the composite at room temperature was mainly adhesive wear.
On Electric Conductivity of Greases
Authors: Reddy Akepati Bhaskar , Shah Faiz Ullah , Leckner Johan , Rutland Mark , Glavatskih Sergei 
Published: February 2022

Abstract
The development of new lubricant systems compatible with modern e-drive conditions, including stray voltages and currents, has gained momentum in recent years. One of the strategies being widely evaluated to achieve these goals is the development of conductive lubricants. Greases, however, have a complex architecture which renders measurement and analysis of their electrical properties challenging; this has severely limited the implementation of the strategy for this class of materials. In this work, a measurement methodology implementing electrochemical impedance spectroscopy to evaluate the electrical properties of grease samples is introduced. Compared to the commonly used conductivity meters, this method, through its multi-frequency alternating current (AC) impedance measurement approach, is able to effectively distinguish the separate contributions of the bulk and the sample-electrode interface to the measured electrical response. Thus, the bulk conductivity of a range of greases with different electrical properties could be obtained independently of their interfacial behavior at the electrode. The temperature dependent bulk conductivity of lithium complex grease doped with different ionic liquids and non-ionic solids (copper and graphite) has accordingly been evaluated and the rather different conductivity mechanisms explained. Bulk ionic conductivity of neat ionic liquids has also been measured using a liquid sample specific electrochemical cell, which aids in the interpretation of the ionic liquid based greases.