bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multiple interval mapping of QTLs and epistasis for iron toxicity tolerance in segregating population of Indica rice
Authors: JAHAN Nusrat , JAVED Muhammad A. , KHAN Anwar , TABASSUM Bushra , AGHA Syed I. , PARVEEN Samia , MUZAFFAR Nazish 
Published: December 2022

The global average temperature has increased by approximately 0.5 °C, over a last few decades and is projected to continue to increase. Environmental stress factors such as, elevated temperature, salinity, toxic elements (Fe, Al, Cd, Cr, Pb, Zn and As), drought and rising CO2 affect plant growth and make a growing threat to agriculture. Rice is a primary food crop in the world and the establishment of rice crop in acidic soil and in marginal soil is a major goal for the improvement of rice production to fulfill the food security. Among environmental stresses, Fe2+ toxicity is one of the main stresses in limiting the cereal crops production. Tolerant rice genotypes that can tolerate the high concentration of Fe2+ toxicity are the potential source genes for rice tolerance improvement in Fe2+ toxicity. In this research work, the genetic basis of seed germination traits and growth traits was investigated in rice using (multiple interval mapping) MIM. Many rice genotypes serve as source of tolerant against toxic metal ion like Fe2+, could be an important factor in controlling the sever effect of Fe2+ toxicity on germination and seedling growth traits. The F3 progenies of cross between Fe2+ toxicity tolerant cultivar ‘Pokkali’ and susceptible cultivar ‘Pak basmati’ were test against the optimized level of Fe2+ toxicity at germination, to determine the mode of inheritance to Fe2+ toxicity tolerance. Wide range of continues variation was found in F3 progenies. Among the 49 quantitative germination trait and 23 growth trait loci (QTLs) on chromosomes 1, 2, 4, 6, 8 and 9 linked with tolerance to Fe2+ toxicity was mapped. Additionally, 21 QTLs for germination traits and 9 QTLs for growth traits were classified as major QTLs using MIM. For germination and growth traits, notable epistasis between the chromosome 1, 2, 4, 6 and 11 was detected across germination and growth traits. Our results suggest that the tolerance mechanisms at germination and seedling phases could differ for Fe2+ toxicity. QTLs detected in this study for germination and seedling growth could be a source of new alleles for development of tolerance rice to Fe2+ toxicity varieties and transformation, gene cloning and gene editing in the future
Primary cutaneous diffuse large B-cell lymphoma, leg type, in an 80-year-old female patient. Clinical case
Authors: Ryabukhina Yu. E. , Abbasbeyli F. M. , Timofeeva O. L. , Zeynalova P. A. , Zhukov A. G. 
Published: December 2022

Primary cutaneous diffuse large B-cell lymphoma, leg type, is diagnosed in 20-25 % cases of all primary cutaneous B-cell lymphomas, primarily in elderly women (older than 70 years). The disease has aggressive recurrent progression and worse prognosis than other variants. The standard antitumor drug therapy are such regimens as R-CHOP and CHOP-like programs including anthracycline antibiotics. Use of these programs can be limited by the presence of cardiovascular and other concomitant disorders.Due to the limited variety of combinations of antitumor agents, low frequency of diagnosis of this immunomorphological variant of lymphoproliferative disease and absence of a single algorithm of drug therapy, every clinical case is interesting and informative.In the presented clinical case, an 80-year-old female patient with primary cutaneous diffuse large B-cell lymphoma, leg type, and concomitant pathology of the cardiovascular system underwent 2 courses of R-CVP regimen drug therapy without anthracyclines. A significant antitumor clinical effect was achieved in the form of complete tumor regression. Treatment was not accompanied by significant toxicity which allowed to complete therapy.
Use of transoral ultrasonography technique in tongue cancer: Advantages and disadvantages
Authors: Allakhverdieva G. F. , Mudunov A. M. , Batsev A. F. 
Published: December 2022

Aim. To evaluate advantages and disadvantages of transoral ultrasonography (US) in tongue cancer.Materials and methods. US was performed in 165 patients between the ages of 15 and 85 years with malignant tumors of the mobile tongue (74 (44.9 %) women, 91 (55.1 %) men).Among 165 patients, 144 had primary tongue tumor. The study also included 21 (12.7 %) patients with recurrent tumor which clinically could be represented by a true recurrence (tumor development 6 months after the end of treatment) or by continued growth (tumor development less than 6 months after the end of treatment). The study included patients with tongue tumors Т1 - 50 (30.3 %) patients, Т2 - 78 (47.3 %) patients, Т3 - 16.4 % of patients, Т4 - 6.1 % of patients.Three types of approach to tongue tumor visualization were used: submandibular, transoral, and transbuccal with a standard linear transducer (4-9 MHz) and intraoperative linear transducer (5-14 MHz). In total in 165 patients with tongue tumors, 147 (89.1 %) transoral US, 86 (52.1 %) submandibular US and 25 (15.2 %) transbuccal US examinations were performed.Results. Among 165 patients, agreement between the sizes measured using US and histological examination was observed in 142 (86.1 %) patients taking into account 15 % error.With increasing tumor thickness and, correspondingly, T criterion, increased frequency of agreement between US data and histological data was observed. Thus, for T1 stage frequency of agreement with US data was observed in 61.8 % of cases, for Т2 stage in 81.1 % of cases, for Т3 stage in 93.8 %, and for Т4 stage agreement was observed in 100 % of cases.Frequency of agreement with histological data in evaluation of tongue tumor thickness for transoral approach was significantly higher than for submandibular approach (р = 0.014). Transoral technique was more accurate for measurement of thickness of primary tumors - 80.3 % of results agreed with histological examination, and for recurrences frequency of agreement was only 33.3 %. Submandibular approach for primary tumors showed accurate measurements only in 67.6 % of cases, in recurrent tumors in 58.3 % of cases. Transbuccal approach also showed higher measurement accuracy for tumor thickness in primary patients (70.0 %) compared to recurrent tumors (40.0 %).Conclusion. Use of transoral ultrasonography significantly improves clinical staging of tongue tumors at the preoperative stage.
A case of combination treatment of femoral osteosarcoma
Authors: Filimonov A. A. , Kutakov N. M. , Chekini D. A. , Musaev E. M. , Akhov A. O. , Zhukov A. G. , Timofeeva O. L. , Abbasbeyli F. M. , Ryabukhina Yu. E. , Zeynalova P. A. , Fedenko A. A. , Ibragimov E. K. 
Published: December 2022

Osteosarcomas are rare tumors with aggressive biology. It is important to refer such patients to a high-volume center, where an accurate diagnosis and optimal treatment are more likely to be performed. In contrast to Ewing's sarcoma, conventional osteosarcomas are believed to be generally resistant to radiation therapy, and the main treatment modalities are surgery and chemotherapy. In this clinical case, we demonstrate the efficacy of combined treatment of osteosarcoma of the femur.Preoperative chemotherapy allowed to evaluate tumor sensitivity to systemic treatment in vivo and optimize adjuvant treatment after R0 resection which allowed to achieve complete clinical response to treatment.
A Novel Hybrid Spotted Hyena-Swarm Optimization (HS-FFO) Framework for Effective Feature Selection in IOT Based Cloud Security Data
Authors: Lohitha N. Sai , Pounambal M. 
Published: December 2022

Internet of Things (IoT) has gained its major insight in terms of its deployment and applications. Since IoT exhibits more heterogeneous characteristics in transmitting the real time application data, these data are vulnerable to many security threats. To safeguard the data, machine and deep learning based security systems has been proposed. But this system suffers the computational burden that impedes threat detection capability. Hence the feature selection plays an important role in designing the complexity aware IoT systems to defend the security attacks in the system. This paper propose the novel ensemble of spotted hyena with firefly algorithm to choose the best features and minimise the redundant data features that can boost the detection system's computational effectiveness. Firstly, an effective firefly optimized feature correlation method is developed. Then, in order to enhance the exploration and search path, operators of fireflies are combined with Spotted Hyena to assist the swarms in leaving the regionally best solutions. The experimentation has been carried out using the different IoT cloud security datasets such as NSL-KDD-99 , UNSW and CIDCC -001 datasets and contrasted with ten cutting-edge feature extraction techniques, like PSO (particle swarm optimization), BAT, Firefly, ACO(Ant Colony Optimization), Improved PSO, CAT, RAT, Spotted Hyena, SHO and BOC(Bee-Colony Optimization) algorithms. Results demonstrates the proposed hybrid model has achieved the better feature selection mechanism with less convergence time and aids better for intelligent threat detection system with the high performance of detection.
Seismic Response of Nenana Sedimentary Basin, Central Alaska
Authors: Smith Kyle , Tape Carl , Tsai Victor C. 
Published: December 2022

ABSTRACTNenana basin in central Alaska is a long (90 km), narrow (12 km), and deep (7 km) sedimentary basin aligned with an active fault zone producing Mw≥6 earthquakes. From 2015 to 2019, 13 broadband seismic stations were deployed in the region as part of the Fault Locations and Alaska Tectonics from Seismicity project. These stations recorded a wide range of earthquakes, including Mw 3–4 directly below the basin as well as several regional earthquakes Mw&gt;6. These 43 local and regional earthquakes, in addition to five teleseismic events and continuously recorded ambient noise, provide a data set that we use to quantify the response of Nenana basin to the seismic wavefield. We calculate spectral ratios between each station and a bedrock reference station for 48 earthquakes. We find amplification of 11–14 dB (amplification ratio 3.5–5.0) for low frequencies (0.1–0.5 Hz), and 8–15 dB (amplification ratio 2.5–5.6) for high frequencies (0.5–4.0 Hz) on the vertical component. At low frequencies, amplification of the earthquake wavefield agrees well with amplification of seismic noise, with both data sets exhibiting stronger amplification on the horizontal components, in comparison with the vertical component. Furthermore, stations overlying the deeper part of the basin exhibit stronger amplification, whereas stations at the margin of the basin exhibit minimal low-frequency amplification. At higher frequencies, amplification occurs at both deeper basin stations and also marginal basin stations. Our study establishes a catalog of diverse events for future theoretical and numerical studies that can use Nenana basin to better understand the complex influence of sedimentary basins on the seismic wavefield.
Exploring the Role of Influencers and Customer Engagement on Purchase Intention in TikTok Live Streaming Shopping
Authors: Lin Qianyu , Nuangjamnong Chompu 
Published: December 2022

Purpose – The purpose of this study is to explore the role of influencer and customer engagement on purchase intention of live-streaming shopping, taking the TikTok platform as an example. The factor that affects customer engagement is customer trust.
Design/Methodology/Approach – This study examines the variables affecting customer engagement and purchase intention using secondary data analysis and archival research techniques. 400 respondents of TikTok's live streaming shopping service provided the information. Additionally, this study adopted three frameworks from other studies in order to create a new conceptual framework.
Findings – This study examines the factors influencing customer engagement and purchase intention. The results of the study showed that Customer trust (trust in community members, broadcast and product) has an impact on customer engagement. Furthermore, purchase intention is influenced by customer engagement and Influencers’ credibility in (attractiveness, trustworthiness and expertise).
Research Limitations/Implications – Researching the variables that affect customer engagement and purchase intention has several limitations. This study's findings may not be entirely applicable to companies who operate on other live streaming platforms since this study was based on users of the TikTok platform.
Originality/value - This study is on the important influencing variables of customer engagement and purchase intention.
The level of physical activity of women during COVID-19 pandemic
Authors: Dąbrowska-Galas Magdalena , Szymańska Joanna 
Published: December 2022

WstępRegularna aktywność fizyczna (<i>physical activity</i> – PA) niesie za sobą wiele korzyści zdrowotnych. Jednak podczas pandemii COVID-19 (<i>coronavirus disease 19</i>) zmieniły się styl życia, codzienna praca, zachowania społeczne, jakość życia, sposoby i formy spędzania wolnego czasu. Celem badania była ocena wpływu pandemii COVID-19 na poziom PA kobiet w okresie okołomenopauzalnym.Materiał i metodyMateriał badawczy stanowiło 126 kobiet przed wybuchem pandemii i 114 kobiet podczas pandemii COVID-19. Badania prowadzono na terenie Śląska. Narzędziem badawczym były skrócone wersje Międzynarodowego Kwestionariusza Aktywności Fizycznej (International Physical Activity Questionnaire – IPAQ) oraz Skali Oceny Menopauzy (Menopause Rating Scale – MRS).WynikiIstotną statystycznie korelację zaobserwowano w przypadku różnicy w umiarkowanym poziomie PA (627,32 MET-min/tydzień przed COVID-19 i 138,6 podczas COVID-19, p = 0,01) i chodzeniu (1952,25 MET-min/tydzień przed COVID-19 i 422,63 MET-min/tydzień podczas COVID-19, p = 0,03). Wyniki pokazały, że statystycznie uległ skróceniu czas poświęcany na umiarkowaną PA. Średnia liczba dni zmniejszyła się z 2,8 do 0,96 (p = 0,02), a średni czas trwania umiarkowanej PA z 39,92 do 15,61 minuty (p < 0,001).WnioskiPandemia COVID-19 istotnie wpłynęła na poziom PA kobiet w okresie okołomenopauzalnym. Kobiety ćwiczyły znacznie rzadziej, skrócono również czas poświęcany na PA. Jako formę PA badane najchętniej wybierały chód.
COVID-19 MOLECULAR-BASED TESTING CAPACITY IN FIVE CUSTOMARY AREAS OF PAPUA
Authors: Imaniar Clara , Widiyanti Mirna 
Published: December 2022

Background: COVID-19 (Corona Virus Disease-19) is a disease that emerged at the end of December 2019 and was declared a world pandemic by the WHO (World Health Organization) in March 2020. The gold standard for testing for covid-19 until now is molecular-based virus detection with RT-PCR (Real Time-Polymerase Chain Reaction) and TCM (Molecular Rapid Test). In the early of this pandemic, Indonesia, especially Papua, still had difficulty examining COVID-19 due to limited laboratories that could carry out these tests.
Aims: This study aimed to see the laboratory's ability from various regencies representing five customary Papuan areas
Methods: This research was a descriptive study that uses primary data and secondary data collected from the Provincial and Regency Papua COVID-19 Response Acceleration Task Force and the representative hospitals of 5 customary Papuan areas (Saireri, Ha anim, Mee Pago, Lapago, Mamta)
Results: There are several challenges and things that need to be considered by all stakeholders involved in examining COVID-19 in Papua so that the examination capacity can be maximally increased.
Conclusion: Regency that only has GeneXpert are recommended to have qPCR so that the acceleration of COVID-19 testing in Papua Province can be carried out. The qPCR can be procured in several cities/regencies within one customary area so that sample delivery can be done more quickly without having to send samples to Jayapura City
ONLINE TEACHING AND LEARNING DURING THE CORONAVIRUS PANDEMIC: ADVANTAGES AND DISADVANTAGES IN HIGHER EDUCATION
Authors: Saranpuetti Chayaporn , Khajornchaikul Piyatida , Pobkeeree Vallerut 
Published: December 2022

Everything is changing rapidly and the development of technology and information has changed significantly in the last few decades. Education, like other aspects of society, needs to change and adapt appropriately. Online teaching and learning is a new approach for the authors to use information technology via distance learning programs, especially the way relationships and interactions altered between students and teachers or instructors when the Coronavirus disease (COVID-19) pandemic occurred last year. Mahidol University responded to the situation rapidly and announced that academics can use online teaching of students free of charge. The authors of this paper have identified the advantages and disadvantages we have encountered while applying this method of instruction. The online program has made teaching possible but it has disadvantages which may decrease the quality of education. Nevertheless, it was used to replace traditional teaching methods by utilizing the web–based program, Webex Meetings, across the whole university. This new approach has changed and opened horizons earlier than the authors thought and far beyond our beliefs concerning traditional education methods for future generations.
Peran Pengetahuan dan Pengalaman Nasabah Bank Syariah Dalam Memajukan Perbankan Syariah
Authors: Sukardi Sukardi 
Published: December 2022

Bank syariah merupakan bank yang operasionalnya mengikuti syariah agama Islam, bank syariah dikembangkan supaya menjadi mitra masyarakat menggunakan bank yang berkeadilan dan terhindar dari riba. Tujuan penelitian ini adalah (1) menganalisis pengaruh pengalaman terkait bank syariah terhadap pengetahuan bank syariah dan (2) menganalisis pengaruh pengalaman terkait bank syariah terhadap niat menggunakan bank syariah, (3) menganalisis pengaruh pengetahuan terkait bank syariah terhadap niat menggunakan bank syariah. Populasi penelitian ini adalah mahasiswa Fakultas Ekonomi dan Bisnis Universitas Ahmad Dahlan Yogyakarta, dengan sampel 133 responden, teknik mengambil sampel dengan stratified randem sampling dan teknik pengumpulan data dengan angket atau kuesioner. Kuesioner disebarkan dengan google form. Data dianalisis dengan regresi linier berganda dan hasil analisisnya adalah: (1) pengalaman terkait bank syariah tidak berpengaruh terhadap pengetahuan bank syariah, (2) pengalaman terkait bank syariah berpengaruh pada niat menggunakan bank syariah, (3) pengetahuan bank syariah berpengaruh pada niat menggunakan bank syariah.
Relação entre saúde mental e uso de substâncias psicoativas em escolares
Authors: Fogolin Fernandes Beatrice , Xander Russo Letícia , De Lucas Bondezan Kezia de Lucas 
Published: December 2022

A adolescência é uma fase do desenvolvimento de grande exposição e vulnerabilidade a comportamentos de risco, como os relacionados às substâncias psicoativas. Devido ao elevado número de usuários e a experimentação precoce dessas substâncias, há um interesse crescente em identificar os fatores de risco e mecanismos subjacentes associados a esse comportamento. Nesse sentido, o presente artigo busca analisar a relação entre o estado de saúde mental e a experimentação e frequência do uso de drogas lícitas (álcool e tabaco) em escolares. Foram consideradas três variáveis de saúde mental: insônia, solidão e ausência de amigos. Com base nos dados da Pesquisa Nacional de Saúde do Escolar (PeNSE) de 2015, o modelo de regressão logit ordenado foi estimado. As características individuais, o contexto familiar e a região de residência foram incluídas no modelo como covariáveis. Observou-se uma menor probabilidade de nunca ter experimentado substâncias psicoativas, tanto álcool quanto cigarro, em escolares que se sentem sozinhos e apresentam dificuldades para dormir. Além disso, solidão e insônia foram relacionadas com maior frequência ao uso dessas substâncias. Tais resultados fornecem evidências da importância de integrar a saúde mental às políticas públicas e práticas educativas de prevenção e redução do uso de substâncias psicoativas na adolescência.
Module Development with Problem Based Learning (PBL) Model Based on Environmental Wetland to Increase Students’ Learning Outcomes
Authors: Aufa Mohamad Nor , Iriani Rilia , Saadi Parham , Hasbie Muhammad , Fitri Muhammad Awaluddin , Yunita Amalia 
Published: December 2022

<p>Research has been carried out on the development of modules with the Problem Based Learning (PBL) model based on wetland environments on the topic of acid-base solutions. This study aims to determine: the validity, practicality and effectiveness of module development. This study used a research &amp; development design of a 4-D development model that was modified into 3-D, the data collection techniques used a test of student learning outcomes and a questionnaire. The research was conducted at SMAN 3 Banjarmasin with a sample of 10 students of class of XI PMIA 3 for small-scale trials, 24 students of XI PMIA 3 for limited-scale trials, and class of XI PMIA 1 and XI PMIA 2 with total 74 students for testing in a wide scale. Validity can be seen based on the results of the validation, the practicality of the students’ responses, and the effectiveness of the students' learning outcomes. The results showed that the module was considered valid with an average score of 146.4 and a percentage of 91.58% (very valid), practical with a percentage of 82.90% (good), effective with an average N-gain score of 0.84 (high), the average score of N-gain is 0.87 (high) for class of XI PMIA 1 and 0.86 (high) for class of XI PMIA 2. The results of this study indicate that the module with the Problem Based Learning (PBL) model based on the wetland environment on the topic of acid-base solutions is declared valid, practical and effective for use as a learning resource for students.</p><p> <strong><em></em></strong></p>
Effectiveness of The Guided Inquiry-Based Flipped Classroom Learning System on Buffer Solution Materials on Students’ Learning Outcomes
Authors: Hartandi Megi , Mawardi Mawardi 
Published: December 2022

This study aims to reveal the effectiveness of the Guided Inquiry-based Flipped Classroom learning System on the buffer solution material on student learning outcomes. This research was conducted with a non-equivalent control group design using a sample of 72 students divided into a control group and an experimental group. The instrument used in this study was a test of students learning outcomes in the form of a written test for student assessment. The test is carried out by giving pretest (Pretest) and posttest (Posttest) questions that have adjusted to the learning objectives. Based on the study's results, the N-Gain Value found in the experimental class was higher than in the control class, with values of 0.82 and 0.70 respectively. From the results of the t-test using the Microsoft Excel application, t<sub>count</sub> is 2.47, and the t<sub>table</sub> with a significance level of 0.05 is 1.99, so t<sub>count </sub> value is greater than t<sub>table</sub>value. So can be concluded that using the flipped classroom learning system based on guided inquiry on buffer materials effective improves student learning outcomes