bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of a machine learning‐based stroke suicidal ideation prediction model : A retrospective study
Authors: Song Seung Il , Hong Hyeon Taek , Lee Changwoo , Lee Seung Bo 
Published: May 2022

Abstract
Background: Currently, the identification of stroke patients with an increased suicide risk is mainly based on self‐report questionnaires, and this method suffers from a lack of objectivity. This study developed and validated a suicide ideation (SI) prediction model using clinical data and identified SI predictors.Method: Significant variables were selected through traditional statistical analysis based on retrospective data of 385 stroke patients; the data was collected from October 2012 to March 2014. The data was then applied to three boosting models (Xgboost, CatBoost, LGBM) to identify the comparative and best performing models.Results: Demographic variables that showed significant differences between the two groups were age, onset, type, socioeconomic, and education level. Additionally, functional variables also showed a significant difference with regard to ADL and emotion (p<0.05). The CatBoost model (0.900) showed higher performance than the other two models; and depression, anxiety, self-efficacy, and rehabilitation motivation (RM) were found to have high importance. Negative emotions such as depression and anxiety showed a positive relationship with SI and rehabilitation motivation and self-efficacy displayed an inverse relationship with SI.Conclusion: Machine learning-based SI models could augment SI prevention by helping rehabilitation and medical professionals identify high-risk stroke patients in need of SI prevention intervention.
Response of Inflation to the Climate Stress: Evidence from Azerbaijan
Authors: Yusifzada Tural 
Published: May 2022

Abstract
This research analyzes the climate change-related factors’ impact on inflation in Azerbaijan between 2005-2020 and forecasts for the 2021-2030 period. For this purpose, the chain impact of temperature on agricultural producer prices is analyzed by the BVAR model. In the second dimension, the transition requirements to green energy’s effects on inflation are examined through the exchange rate. According to the model results, climate changes’ contribution to inflation is expected to be 1.3 percentage points (pp) in the long run with the normal scenario. On the other hand, climate contribution to inflation is estimated to be 2.2 pp (surpasses half of the inflation target) in the worst scenario of climate change. In the light of these results, the paper highlights the importance of a well-developed climate action plan set by the government and the Central Bank of the Republic of Azerbaijan. JEL Codes: E31, Q54, E37, E58, C32
Text-based recommender system with explanatory capabilities
Authors: Pérez-Núñez Pablo , Díez Jorge , Bahamonde Antonio , Luaces Oscar 
Published: May 2022

Abstract
Recommender systems have proven their usefulness both for companies and customers. The former increase their sales and the latter get a more satisfying shopping experience. These systems can benefit from the advent of explainable artificial intelligence, since a well-explained recommendation will be more convincing and may broaden the customer’s purchasing options. Many approaches offer justifications for their recommendations based on the similarity (in some sense) between users, past purchases, etc., which require some knowledge of the users. In this paper we present a recommender system with explanatory capabilities which is able to deal with the so-called cold-start problem, since it does not require any previous knowledge of the user. Our method learns the relationship between the products and some relevant words appearing in the textual reviews written by previous customers for those products. Then, starting from the textual query of a user’s request for recommendation, our approach elaborates a list of products and explains each recommendation on the basis of the compatibility between the query’s words and the relevant terms for each product.
Congenital Orbital Teratoma: A case report with fetal presentation
Authors: Wheeler Matthew , Pergoretti Kelly , Gore Sri , D'Arco Felice , Merve Ashirward , Mankad Kshitij 
Published: May 2022

Abstract
Congenital orbital teratomas are rare entities with few case reports detailing their prenatal and perinatal imaging features. We present the case of a congenital orbital teratoma initially detected as cystic lesion on prenatal ultrasound, with fetal and postnatal imaging showing evolution of characteristic MRI appearances. Knowledge of these appearances and the ability to diagnose these rare entities in fetal life can aid management and operative planning in the immediate postnatal period.
Mapping and Assessing Spatial Extent of Floods from Multitemporal Synthetic Aperture Radar Images: A Case Study over Chennai City, India
Authors: Sundaram Sreechanth , Devaraj Suresh , Yarrakula Kiran 
Published: May 2022

Abstract
Urban floods are more concerned in recent days due to their substantial effect in loss of human lives and properties. Due to climate change, urban floods are frequently observed in many parts of the world. Flood events in Chennai city is a frequent scenario due to rapid increase in the density of population. Adyar river watershed and surrounding urban cover is focused in the present study. The present study aims at mapping flooded region using Sentinel 1 datasets over Chennai city. Series of Sentinel-1A image is collected before, during and after floods for mapping the extent of flood and mapping risk zones in Adyar watershed. Methodologies such as ISODATA Technique, Multi-Temporal Analysis, Thresholding Method, PCA and ICA Analysis and Grey Level Co-Occurrence Matrix are adopted for the extraction of flooded extent from the SAR datasets. Analysis performed over the Chennai city provided promising results in the extraction of flooded extent with Thresholding Method and Grey Level Co-Occurrence Matrix being the dominant of all the methods. Though higher accuracy is obtained in the extraction of flooded extent, limitation of layover, foreshortening and shadow is experienced in the built up region for the extraction of flooded pixels.
Association of Greenness Exposure with Asthma, Allergic rhinitis: A Systematic Review and Meta-analysis
Authors: Wu Birong , Guo Xianwei , Liang Mingming , Sun Chenyu , Gao Juan , Xie Peng , Feng Linya , Xia Weihang , Ma Shaodi , Liu Haixia , Sun Yehuan 
Published: May 2022

Abstract
Peer-reviewed literature was systematically searched before 23 December 2021 to summarize existed evidence on the relationship between greenness exposure (residential greenery/greenery around schools) and some allergic respiratory diseases, including asthma and allergic rhinitis (AR). A systematic review was conducted, together with a meta-analysis. Pooled odds ratio (OR) with 95% confidence interval (CI) was used to estimate the effect of Normalized Difference Vegetation Index (NDVI) on asthma and AR. Cochran's Q chi-square test and I2 statistics were used to assess heterogeneity and sensitivity analysis was performed for high heterogeneity. Publication bias was assessed by Egger's tests. This study finally included 26 articles with positive, negative or no correlation between greenness exposure and asthma and AR. Eight of these studies underwent finite meta-analysis in different groups. The results showed no relationship between NDVI and asthma or AR. Two articles with high heterogeneity were identified by sensitivity analysis. There was no publication bias. This study protocol was registered with PROSPERO, number CRD42022299861.
Cost Sensitivity, Partisan Cues, and Support for the Green New Deal
Authors: Benegal Salil , Green Jon 
Published: May 2022

Abstract
Opponents of climate policy proposals frequently ground their objections in terms of costs. However, it is unclear whether these objections are persuasive to voters considering whether to support such programs. Not only do people have difficulties in understanding large numbers, partisans in particular may place more weight on the originator of a given proposal – supporting it if their own party proposed it, and opposing it otherwise. We test these dynamics using a survey experiment that varied the costs associated with real-world climate policy proposals attributed to each of the two major U.S. political parties, compared to a control group where no cost was made salient. We find little evidence that citizens are systematically sensitive to program cost, and that partisans tend to prefer policies proposed by their own party. The results provide reason for skepticism that cost-based objections to climate spending programs are persuasive at scale, after accounting for partisan cue-taking.
Preventive Strategies for Anthracyclines and Trastuzumab induced Cardiotoxicity: A systematic review and meta-analysis
Authors: Oliveira Cátia , Campos Rui , Flores Rui , Fontes Raquel , Pereira Vitor Hugo 
Published: May 2022

Abstract
Background
Despite the widespread use of anthracyclines (ANT) and anti-HER2 antibodies as trastuzumab (TZB) in chemotherapy schemes, it is known the potential cardiotoxic effects that can limit its use.
Aim
To study the benefit of drugs commonly used to treat heart failure with reduced ejection fraction or drugs known for an antioxidative effect on the prevention of ANT and TZB induced cardiotoxicity.
Methods
an extensive search was made in PubMed, Embase and Cochrane trials since inception to November 2020. Randomized controlled trials in which the drugs mentioned were given to adult patients treated with ANT and/or TZB were included. The outcomes of interest were left ventricular ejection fraction (LVEF), global longitudinal strain (GLS), E/A ratio, E/e’ ratio, left atrium diameter, BNP/NT-pro-BNP and Troponin I levels. Subgroup analysis were made accounting for combinations of exposure to ANT and/or TZB
Results
24 randomized controlled trials were included with a total of 3159 participants (94% were women). A meta-analysis showed betablockers to lower E/A ratio (combined effect of 0,12 decrease (95% CI:[0,05; 0,19], I2 = 11%), and did not show any effect on LVEF, except perhaps for nebivolol, which in one study demonstrated a mean difference of 6,30% [3,32; 9,28] (p < 0,05) between groups. Angiotensin Conversion Enzyme Inhibitors and Angiotensin Receptor Antagonists did not show any protective effect. Dexrazoxane also showed to reduce the incidence of cardiac events with a combined risk ratio of 0,28 (95% CI: [0,16; 0,47], I2 = 9%). Rosuvastatin also showed to preserve LVEF and left atrium diameter and spironolactone showed to preserve LVEF, E/A and E/e’ ratio, however with only one trial each.
Conclusions
Prophylactic administration of either beta-blockers or dexrazoxane may prevent the development of ANT and TZB cardiotoxicity and therefore allow for fewer treatment interruptions and a better long-term prognosis of cancer patients.
Myricitrin promotes osteogenesis and prevents ovariectomy bone loss through PI3K/AKT signaling pathway
Authors: Li Jianliang , Mai JiaLe , Zhang Meng , He Qi , Ma YanHuai , Xiao Jiacong , Li Miao , Chen WeiJian , Li Zhen , Gong Dawei , Chen Shuai , Pan ZhaoFeng , Li Shaocong , Wang Haibin 
Published: May 2022

Abstract
Background: Osteoporosis is characterized by reduced bone mass and destruction of trabecular bone microstructure, increasing fracture risk. Newly marketed drugs have certain advantages in osteoporosis, but high health care expenditures and side effects limit their application. Therefore, it is urgent to explore new approaches to break the therapeutic deadlock in the current clinical condition. Myricitrin has many biological activities. However, the effect on antiosteoporosis has not fully been elucidated yet.Methods: The effect of myricitrin on the proliferation of immortalized bone marrow mesenchymal stem cells was evaluated using Cell Counting Kit-8 assays. Alizarin Red staining, Alkaline phosphatase staining, and activity were performed to elucidate osteogenesis. qRT-PCR and Western blot were performed to evaluate the expression of osteo-specific genes and proteins. To screen for candidate targets, sequencing of mRNA transcriptome genes was used through bioinformatics analysis. Western blot and Molecular docking analysis were used to examine target signaling markers. Rescue experiments were used to confirm myricitrin can enhance osteogenic differentiation of imBMSCs reversely. Moreover, ovariectomy mice were used to assess the effect of myricitrin on bone loss in vivo by Western blot, Micro-CT, Hematoxylin and Eosin staining, and immunochemistry.Results: Myricitrin can significantly enhance osteo-specific genes and proteins expression, alkaline phosphatase activity, and calcium deposition in imBMSCs in vitro. These phenomena were accompanied by an upregulation of the PI3K/AKT signaling pathway via bioinformatics analysis and Western blot. In addition, the improvement of osteogenesis due to myricitrin intervention was partially reversed by copanlisib, which is a PI3K inhibitor. Osteopontin (OPN), osteoprotegerin (OPG), p-PI3K, and p-AKT were significantly increased in the low dose and high dose myricitrin groups compared with the OVX group. Micro-CT, H&E staining, and immunochemistry showed that bone mass was significantly increased in low dose and high dose groups compared with the OVX group. Furthermore, myricitrin can attenuate bone loss in ovariectomy mice.Conclusion: These data suggest that myricitrin enhances the osteogenic differentiation of imBMSCs, partly via activation of the PI3K/AKT signaling pathway. Myricitrin may be a potential drug development for the treatment of postmenopausal osteoporosis.
Effect of patient position change during the colonoscopy withdrawal phase on increasing adenoma detection rate: a randomized controlled trial
Authors: Emami Abdolreza , Shirvani Javad Shokri , Alhooei Saman , Hosseini Akramasadat , Ahangar Hemmat Gholinia 
Published: May 2022

Abstract
Background: Improvement in adenoma detection rate (ADR) reduces colorectal cancer incidence by increasing the colonoscopy quality. Using dynamic patient position changes during the withdrawal phase has shown promise in increasing ADR. We conducted this study to assess the effectiveness of the supine position on the improvement of ADR to improve its feasibility and avoid frequent patient position changes, particularly in sedated patients.Methods: This was a randomized, single-blind, parallel-group, single-center study implemented in the Mehregan private in Babol. Inclusion criteria were 40 to 85 years old, 4 L application of polyethylene glycol from the day before the procedure, no history of inflammatory bowel disease, bowel surgery, musculoskeletal problems, and negative familial history of colorectal cancer. Patients were allocated in a 1:1 ratio to the supine or left lateral positions during the withdrawal phase. All colonoscopies were performed by a single physician using a Fujifilm colonoscope. A P-value of <0.005 was considered statistically significant.Results: A total of 880 patients were assessed for eligibility, of which 472 patients were included in the final analysis; 53.4% were female, the mean age of participants was 55.86±10.30 years old, 95.1% of patients had adequate bowel preparation, and adenomatous polyps were the most common histopathologic type (63.7%). Despite the intervention group’s higher rate of ADR and PDR (19.5% vs. 17.7% for ADR and 27.2% vs. 26.5% for PDR), no statistically significant difference in ADR or PDR was detected (P=0.613 and 0.866). Conclusion: No statistical significance was observed despite the increase in ADR when the supine position was used exclusively during the withdrawal phase. As a result, we recommend that the dynamic position change method be used if a position change is required. Nonetheless, additional research is required to determine a more effective alternative to dynamic position change in obese or heavily sedated patients.Trial registration: IRCTID: IRCT20110721007080N5, registration date: 04/05/2020
Vortex dynamics downstream two-side lateral expansion in shallow open channel
Authors: Han Lei , Guo Chuanliang , Sun Erliang , Tan Heping 
Published: May 2022

Abstract
As an expansion existing in an open channel, a recirculation zone is formed downstream the expansion, and then a mixing layer is formed between the main flow zone, where vortex structures exist which dominate the material and momentum exchange process between the former two zones. This research focuses on the vortex dynamics downstream two-side lateral expansions in shallow open channels. First, the length of the recirculation zone is measured in a sudden lateral expansion channel by particle image velocimetry and also simulated by large eddy simulation. Second, to analyze the vortex dynamics, the flow fields are reconstructed based on proper orthogonal decomposition (POD). POD results indicate that the vortex energy decreases as S increases. Furthermore, the Reynolds stress and turbulent kinetic energy characteristics are compared among different S conditions that could be linked to the vortex energy dissipation process. Finally, a one-dimensional spectrum analysis is performed in the center of the mixing layer that reflects the vortex shedding frequency of the vortex. In summary, in the small S condition, the flow is significantly more confined by the free surface, the vortex energy peak frequency decays more slowly, and the vortex energy dissi-pation slows down.
Regolith at Chang'E-5 landing site: mature lunar soils from Fe-rich and young mare basalts
Authors: Lu Xuejin , Chen Jian , Ling Zongcheng , Liu Changqing , Fu Xiaohui , Qiao Le , Zhang Jiang , Cao Haijun , Liu Jianzhong 
Published: May 2022

Abstract
Space weathering process on airless bodies produces metallic iron (Fe0) particles widely existing in the rim and interior of mineral grains, which complicate visible and near-infrared spectra of surface materials. Although these space weathering products and their spectroscopic effects on the Moon have been extensively investigated based on returned Apollo samples and orbital datasets, the Chang’E-5 (CE-5) mission provides an unprecedent opportunity to couple information gained from newly returned CE-5 samples with in situ observations and investigate space weathering process on extremely Fe-rich basalts. The in situ detections, returned soils, and orbital measurements of soil maturity at CE-5 landing site are cross-validated and provide a new ground truth (Is/FeO value of 66.4) for lunar surface. The age of Xu Guangqi crater was determined to be 240 ~ 300 Ma and its ejecta is the main source of CE-5 soils. Further, abundant larger-sized Fe0 particles were observed in the regolith at CE-5 landing site, which indicates that the inherited Fe0 particles from late-stage mare basalts and dense clustering of oversaturated Fe0 in extremely FeO-rich (> 17 wt.%) basalts both contribute to observed Fe0 abundances. We suggest that space weathering of Fe-richer basalt generates Fe0 particles with larger grain size and faster production rate.
Evaluation of surface urban heat island intensity in arid environments (case study: Isfahan metropolitan area)
Authors: Montazeri Majid , Masoodian Seyed Abolfazl , Guo Xulin 
Published: May 2022

Abstract
Heat island is formed due to the expansion of a city in a vast geographic area. The traditional index is used to describe the urban heat island based on the temperature difference between the urban and rural areas. Other indices have been suggested in the literature for this purpose. However, the heat island characteristics depend on the background climate of the place where the city is located. Therefore, an index was defined based on the background climate of the Isfahan metropolitan area in order to quantify the heat island intensity. This new index is based on the representative pixels of the urban and the non-urban areas. For this purpose, the MODIS land cover type product (MCD12Q1) data was used to distinguish between the urban and non-urban areas. Also, the data from the MODIS/Terra/Aqua land surface temperature product (MOD11A1/MYD11A1) from 2000 to 2016 was utilized for the day time and night time to study the heat island intensity. Then, the representative pixels of urban and the non-urban areas were identified using the spatial correlation method and the heat island index was calculated for the metropolitan area of Isfahan. The study showed that the frequency distribution for the nighttime heat island index in the metropolitan area of Isfahan follows a normal distribution and is often 3.5-4 K above the temperature of the surrounding areas at night. Investigating the temporal and spatial behavior of surface urban heat island in the metropolitan area of Isfahan showed that the intensity of the surface urban heat island is maximum in January and becomes weaker in summer. The 365-day floating mean of the surface urban heat island showed that this index has increased in recent years. The core of heat island in the metropolitan area of Isfahan is extended to downtown areas where the oldest part of the city is located.
Plant functional, biogeographical and phylogenetic diversity are related to native and non-native plant abundance in invaded Hawaiian forests
Authors: Hibit Joshua , Daehler Curtis C. 
Published: May 2022

Abstract
Numerous introduced species from cosmopolitan biogeographic origins have naturalized in the Hawaiian Islands and are spreading while native plant cover has declined. Phylogenetic, functional, and biogeographical diversity have been shown to influence invasion success, but relationships between these diversity measures and native plant abundance in invaded oceanic island forests has not been well established. Here we surveyed plant cover in 50 plots (400 m2) on the island of Oʻahu, Hawaiʻi. We measured four performance-related functional traits (specific leaf area, stem specific density, seed dry mass, and maximum plant height), and determined the growth form of each species. We calculated the differences between native and non-native community weighted mean trait values and assessed whether these differences, as well as measures of diversity, were associated with native and non-native cover. We found that average trait values were significantly higher for maximum height in natives, and significantly higher for specific leaf area and stem specific density in non-natives. The difference in maximum height of natives and non-natives was correlated with reduced non-native cover. Functional divergence and phylogenetic diversity of natives were positively correlated with native cover. Functional divergence and richness of non-natives were correlated with non-native cover. Biogeographical diversity was not significantly correlated with non-native cover but had indirect effects via its significant correlation with non-native functional richness, which was positively correlated with non-native cover. These findings suggest that diversity and competition for light may be important determinants of native and non-native species cover in invaded Hawaiian forests. An increasing number of distinct non-native plant introductions is thus likely to be associated with continued declines in native plant cover.