bluuebunny/crossref_metadata_2025_split huggingface dataset:
Human infection with a reassortment avian influenza A H3N8 virus: an epidemiological investigation study
Authors: Bao Pengtao , Liu Yang , Zhang Xiaoai , Fan Hang , Zhao Jie , Mu Mi , Li Haiyang , Wang Yanhe , Ge Honghan , Li Shuang , Yang Xin , Cui Qianqian , Chen Rui , Gao Liang , Sun Zhihua , Gao Lizhen , Qiu Shuang , Liu Xuchun , Horby Peter W. , Li Xiubin , Fang Liqun , Liu Wei 
Published: November 2022

AbstractA four-year-old boy developed recurrent fever and severe pneumonia in April, 2022. High-throughput sequencing revealed a reassortant avian influenza A-H3N8 virus (A/Henan/ZMD-22-2/2022(H3N8) with avian-origin HA and NA genes. The six internal genes were acquired from Eurasian lineage H9N2 viruses. Molecular substitutions analysis revealed the haemagglutin retained avian-like receptor binding specificity but that PB2 genes possessed sequence changes (E627K) associated with increased virulence and transmissibility in mammalian animal models. The patient developed respiratory failure, liver, renal, coagulation dysfunction and sepsis. Endotracheal intubation and extracorporeal membrane oxygenation were administered. H3N8 RNA was detected from nasopharyngeal swab of a dog, anal swab of a cat, and environmental samples collected in the patient’s house. The full-length HA sequences from the dog and cat were identical to the sequence from the patient. No influenza-like illness was developed and no H3N8 RNA was identified in family members. Serological testing revealed neutralizing antibody response against ZMD-22-2 virus in the patient and three family members. Our results suggest that a triple reassortant H3N8 caused severe human disease. There is some evidence of mammalian adaptation, possible via an intermediary mammalian species, but no evidence of person-to-person transmission. The potential threat from avian influenza viruses warrants continuous evaluation and mitigation.
Fertilization mode differentially impacts the evolution of vertebrate sperm components
Authors: Kahrl Ariel F. , Snook Rhonda R. , Fitzpatrick John L. 
Published: November 2022

AbstractEnvironmental change frequently drives morphological diversification, including at the cellular level. Transitions in the environment where fertilization occurs (i.e., fertilization mode) are hypothesized to be a driver of the extreme diversity in sperm morphology observed in animals. Yet how fertilization mode impacts the evolution of sperm components—head, midpiece, and flagellum—each with different functional roles that must act as an integrated unit remains unclear. Here, we test this hypothesis by examining the evolution of sperm component lengths across 1103 species of vertebrates varying in fertilization mode (external vs. internal fertilization). Sperm component length is explained in part by fertilization mode across vertebrates, but how fertilization mode influences sperm evolution varies among sperm components and vertebrate clades. We also identify evolutionary responses not influenced by fertilization mode: midpieces evolve rapidly in both external and internal fertilizers. Fertilization mode thus influences vertebrate sperm evolution through complex component- and clade-specific evolutionary responses.
Hole-doping induced ferromagnetism in 2D materials
Authors: Meng Ruishen , da Costa Pereira Lino , Locquet Jean-Pierre , Afanas’ev Valeri , Pourtois Geoffrey , Houssa Michel 
Published: November 2022

AbstractTwo-dimensional (2D) ferromagnetic materials are considered as promising candidates for the future generations of spintronic devices. Yet, 2D materials with intrinsic ferromagnetism are scarce. Hereby, high-throughput first-principles simulations are performed to screen 2D materials that present a non-magnetic to a ferromagnetic transition upon hole doping. A global evolutionary search is subsequently performed to identify alternative possible atomic structures of the eligible candidates, and 122 materials exhibiting a hole-doping induced ferromagnetism are identified. Their energetic and dynamic stability, as well as magnetic properties under hole doping are investigated systematically. Half of these 2D materials are metal halides, followed by chalcogenides, oxides, and nitrides, some of them having predicted Curie temperatures above 300 K. The exchange interactions responsible for the ferromagnetic order are also discussed. This work not only provides theoretical insights into hole-doped 2D ferromagnetic materials, but also enriches the family of 2D magnetic materials for possible spintronic applications.
Crystal twins: self-supervised learning for crystalline material property prediction
Authors: Magar Rishikesh , Wang Yuyang , Barati Farimani Amir 
Published: November 2022

AbstractMachine learning (ML) models have been widely successful in the prediction of material properties. However, large labeled datasets required for training accurate ML models are elusive and computationally expensive to generate. Recent advances in Self-Supervised Learning (SSL) frameworks capable of training ML models on unlabeled data mitigate this problem and demonstrate superior performance in computer vision and natural language processing. Drawing inspiration from the developments in SSL, we introduce Crystal Twins (CT): a generic SSL method for crystalline materials property prediction that can leverage large unlabeled datasets. CT adapts a twin Graph Neural Network (GNN) and learns representations by forcing graph latent embeddings of augmented instances obtained from the same crystalline system to be similar. We implement Barlow Twins and SimSiam frameworks in CT. By sharing the pre-trained weights when fine-tuning the GNN for downstream tasks, we significantly improve the performance of GNN on 14 challenging material property prediction benchmarks.
Computational screening of transition metal-doped CdS for photocatalytic hydrogen production
Authors: Li Yuting , Bahamon Daniel , Sinnokrot Mutasem , Vega Lourdes F. 
Published: November 2022

AbstractA novel computational screening study of single transition metal (TM), TM-doped, and dual TMs-doped on CdS (110) surfaces via DFT calculations is presented, focusing on their stability and catalytic activity, searching for efficient photocatalysts for hydrogen production. Criteria based on key performance descriptors allowed to fine-tune the selection. Results indicate that TM dopants can reduce the energy band gap and enhance impurity d-states. Pt, Rh, and Pd were found to be the best dopants in TM-doped CdS, since their $$\left| {\Delta G_H} \right|$$

Δ

G

H

is 80% smaller compared to the pristine CdS surface. Moreover, TM1-TM2-co-doped CdS catalysts show better performance for the hydrogen evolution reaction (HER) due to synergistic effects of the two TMs, where Co-Pt, Pd-Pt and Co-Rh co-doping CdS significantly reduced $$\left| {\Delta G_H} \right|$$

Δ

G

H

to less than 0.1 eV. Results point out four promising novel co-catalysts (i.e., Co, Co-Pt, Co-Rh, Rh-Ag) with very good performance in HER, to be further explored in experimental studies.
Highly sensitive active-powering pressure sensor enabled by integration of double-rough surface hydrogel and flexible batteries
Authors: Huang Yuan , Liu Binbin , Zhang Wenyue , Qu Gangrui , Jin Shunyu , Li Xianbo , Nie Zanxiang , Zhou Hang 
Published: November 2022

AbstractA conductive, elastic, and biocompatible hybrid network hydrogel was prepared by cross-linking of locust bean gum, polyvinyl alcohol, and carbon nanotubes, yielding a rough top surface and smooth bottom surface. The merging of the two pieces of hydrogel flat face to flat face forms a highly elastic hydrogel with double-rough surfaces. A piezoresistive sensor assembled with the double-rough surface hydrogel sandwiched between two carbon cloth electrodes exhibits a high sensitivity (20.5 kPa-1, 0-1kPa), a broad detection range (0.1–100 kPa) and a reliable response for 1000 cycles. The rough contact area between the hydrogels and the carbon cloth is found critical in achieving ultra-high sensitivities in the low-pressure range. Moreover, further monolithic integration of the sensor with a flexible solid-state zinc ion battery ensures the self-powering of the sensor for various human motions detection applications.
Stress-assisted corrosion behaviour of Hastelloy N in FLiNaK molten salt environment
Authors: Gu Yufen , Zhang Wenzhu , Xu Youwei , Shi Yu , Volodymyr Korzhyk 
Published: November 2022

AbstractThe use of molten-salt–based energy production and storage systems requires high-temperature corrosion- and creep-resistant structural materials. This study investigated the microstructure evolution and corrosion characteristics of Hastelloy N under working stress in a molten salt environment. Selective diffusion of Cr at the grain boundaries (GBs) of the Hastelloy N degraded the properties of the GBs, making them preferred locations for corrosion crack invasion. Stress further promoted Cr diffusion and accelerated GB carbide precipitation, thereby forming a corrosion couple between the carbide and matrix that facilitated the expansion of intergranular corrosion cracks into the grains. These findings are useful for providing advances in the design of novel structural alloys with extraordinary property-microstructure stability combinations for resistant to complex molten salt environments.
Al2O3-modified 7YSZ thermal barrier coatings for protection against volcanic ash corrosion
Authors: Zhang Xiaofeng , Zhuo Xueshi , Fan Zhengjie , Mao Jie , Deng Chunming , Deng Changguang , Mei Xuesong , Cui Jianlei , Zhou Kesong , Liu Min 
Published: November 2022

AbstractTo prevent volcanic ash corrosion using thermal barrier coatings (TBCs), a novel method using Al2O3-modification was proposed to reduce molten CMAS wettability on TBCs surface through a lotus effect. Plasma spray-physical vapor deposition (PS-PVD), a third-generation method for TBCs fabrication, was adopted to deposit 7YSZ TBCs with a feather-like microstructure. Then, Al2O3 modification was introduced to fabricate a dense Al2O3 overlay with nano/micro-sized grains on the TBCs surface. The wetting ability of CMAS on APS/EB-PVD/PS-PVD 7YSZ TBCs was comparatively in situ observed at 1250 °C for 3600 s. The results indicated that the dense Al2O3 overlay inhibited penetration of molten CMAS. Additionally, the micro/nano dual-sized structure, which is similar to the papillary structure of a lotus leaf, reduced molten CMAS wettability on the TBCs surface. The results demonstrated that the Al2O3-modified TBCs had better CMAS corrosion resistance than the as-deposited APS/EB-PVD/PS-PVD TBCs.
Attempts to quit smoking, use of smoking cessation methods, and associated characteristics among COPD patients
Authors: Pashutina Yekaterina , Kotz Daniel , Kastaun Sabrina 
Published: November 2022

AbstractWe explored past-year quit attempts, cessation methods used, and associations with sociodemographic, smoking, and health-related characteristics among smoking patients with chronic obstructive pulmonary disease (COPD) in Germany. Cross-sectional survey data of 509 past-year smokers (current smokers and ≤12 months abstinent) with COPD (ICD-10 code J44.x and FEV1/FVC <0.70) from 19 pulmonary primary care practices were used. Associations were explored between age, sex, educational qualification, lung function, urges to smoke, psychological distress, and (a) ≥1 past-year quit attempt (yes/no), (b) use of ≥1 evidence-based smoking cessation method (yes/no). Of all patients, 48.5% (n = 247, 95% confidence interval (CI) 44.2–52.9) reported ≥1 past-year quit attempt. Such an attempt was positively associated with the male sex (Odds Ratio (OR) = 1.50, 95% CI 1.01–2.24) and negatively associated with time spent with urges to smoke (OR = 0.69, 95% CI 0.52–0.91). During the most recent past-year quit attempt, one-third of the patients used ≥1 evidence-based smoking cessation method (31.2%, 95% CI 25.4–37.0), which was positively associated with the strength of urges to smoke (OR = 1.62, 95% CI 1.09–2.41). Combined behavioural and pharmacological treatments were used by 4.0% (n = 10, 95% CI 1.6–6.5). Electronic cigarettes were used most frequently (21.5%, 95% CI 16.3–26.6). Although a high proportion of COPD patients in German pulmonary primary care attempt to quit smoking, only a few of them use evidence-based methods as assistance for quitting.
Bordetella pertussis whole cell immunization protects against Pseudomonas aeruginosa infections
Authors: Blackwood Catherine B. , Mateu-Borrás Margalida , Sen-Kilic Emel , Pyles Gage M. , Miller Sarah Jo , Weaver Kelly L. , Witt William T. , Huckaby Annalisa B. , Kang Jason , Chandler Courtney E. , Ernst Robert K. , Heath Damron F. , Barbier Mariette 
Published: November 2022

AbstractWhole cell vaccines are complex mixtures of antigens, immunogens, and sometimes adjuvants that can trigger potent and protective immune responses. In some instances, such as whole cell Bordetella pertussis vaccination, the immune response to vaccination extends beyond the pathogen the vaccine was intended for and contributes to protection against other clinically significant pathogens. In this study, we describe how B. pertussis whole cell vaccination protects mice against acute pneumonia caused by Pseudomonas aeruginosa. Using ELISA and western blot, we identified that B. pertussis whole cell vaccination induces production of antibodies that bind to lab-adapted and clinical strains of P. aeruginosa, regardless of immunization route or adjuvant used. The cross-reactive antigens were identified using immunoprecipitation, mass spectrometry, and subsequent immunoblotting. We determined that B. pertussis GroEL and OmpA present in the B. pertussis whole cell vaccine led to production of antibodies against P. aeruginosa GroEL and OprF, respectively. Finally, we showed that recombinant B. pertussis OmpA was sufficient to induce protection against P. aeruginosa acute murine pneumonia. This study highlights the potential for use of B. pertussis OmpA as a vaccine antigen for prevention of P. aeruginosa infection, and the potential of broadly protective antigens for vaccine development.
Coevolution of religious and political authority in Austronesian societies
Authors: Sheehan Oliver , Watts Joseph , Gray Russell D. , Bulbulia Joseph , Claessens Scott , Ringen Erik J. , Atkinson Quentin D. 
Published: November 2022

AbstractAuthority, an institutionalized form of social power, is one of the defining features of the large-scale societies that evolved during the Holocene. Religious and political authority have deep histories in human societies and are clearly interdependent, but the nature of their relationship and its evolution over time is contested. We purpose-built an ethnographic dataset of 97 Austronesian societies and used phylogenetic methods to address two long-standing questions about the evolution of religious and political authority: first, how these two institutions have coevolved, and second, whether religious and political authority have tended to become more or less differentiated. We found evidence for mutual interdependence between religious and political authority but no evidence for or against a long-term pattern of differentiation or unification in systems of religious and political authority. Our results provide insight into how political and religious authority have worked synergistically over millennia during the evolution of large-scale societies.
Divergent SARS-CoV-2 variant emerges in white-tailed deer with deer-to-human transmission
Authors: Pickering Bradley , Lung Oliver , Maguire Finlay , Kruczkiewicz Peter , Kotwa Jonathon D. , Buchanan Tore , Gagnier Marianne , Guthrie Jennifer L. , Jardine Claire M. , Marchand-Austin Alex , Massé Ariane , McClinchey Heather , Nirmalarajah Kuganya , Aftanas Patryk , Blais-Savoie Juliette , Chee Hsien-Yao , Chien Emily , Yim Winfield , Banete Andra , Griffin Bryan D. , Yip Lily , Goolia Melissa , Suderman Matthew , Pinette Mathieu , Smith Greg , Sullivan Daniel , Rudar Josip , Vernygora Oksana , Adey Elizabeth , Nebroski Michelle , Goyette Guillaume , Finzi Andrés , Laroche Geneviève , Ariana Ardeshir , Vahkal Brett , Côté Marceline , McGeer Allison J. , Nituch Larissa , Mubareka Samira , Bowman Jeff 
Published: November 2022

AbstractWildlife reservoirs of broad-host-range viruses have the potential to enable evolution of viral variants that can emerge to infect humans. In North America, there is phylogenomic evidence of continual transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from humans to white-tailed deer (Odocoileus virginianus) through unknown means, but no evidence of transmission from deer to humans. We carried out an observational surveillance study in Ontario, Canada during November and December 2021 (n = 300 deer) and identified a highly divergent lineage of SARS-CoV-2 in white-tailed deer (B.1.641). This lineage is one of the most divergent SARS-CoV-2 lineages identified so far, with 76 mutations (including 37 previously associated with non-human mammalian hosts). From a set of five complete and two partial deer-derived viral genomes we applied phylogenomic, recombination, selection and mutation spectrum analyses, which provided evidence for evolution and transmission in deer and a shared ancestry with mink-derived virus. Our analysis also revealed an epidemiologically linked human infection. Taken together, our findings provide evidence for sustained evolution of SARS-CoV-2 in white-tailed deer and of deer-to-human transmission.
Near-real-time daily estimates of fossil fuel CO2 emissions from major high-emission cities in China
Authors: Huo Da , Liu Kai , Liu Jianwu , Huang Yingjian , Sun Taochun , Sun Yun , Si Caomingzhe , Liu Jinjie , Huang Xiaoting , Qiu Jian , Wang Haijin , Cui Duo , Zhu Biqing , Deng Zhu , Ke Piyu , Shan Yuli , Boucher Olivier , Dannet Grégoire , Liang Gaoqi , Zhao Junhua , Chen Lei , Zhang Qian , Ciais Philippe , Zhou Wenwen , Liu Zhu 
Published: November 2022

AbstractCities in China are on the frontline of low-carbon transition which requires monitoring city-level emissions with low-latency to support timely climate actions. Most existing CO2emission inventories lag reality by more than one year and only provide annual totals. To improve the timeliness and temporal resolution of city-level emission inventories, we present Carbon Monitor Cities-China (CMCC), a near-real-time dataset of daily CO2emissions from fossil fuel and cement production for 48 major high-emission cities in China. This dataset provides territory-based emission estimates from 2020-01-01 to 2021-12-31 for five sectors: power generation, residential (buildings and services), industry, ground transportation, and aviation. CMCC is developed based on an innovative framework that integrates bottom-up inventory construction and daily emission estimates from sectoral activities and models. Annual emissions show reasonable agreement with other datasets, and uncertainty ranges are estimated for each city and sector. CMCC provides valuable daily emission estimates that enable low-latency mitigation monitoring for cities in China.
Chitosan oligosaccharide alleviates renal fibrosis through reducing oxidative stress damage and regulating TGF-β1/Smads pathway
Authors: Wu Jun , Xu Yingtao , Geng Zikai , Zhou Jianqing , Xiong Qingping , Xu Zhimeng , Li Hailun , Han Yun 
Published: November 2022

AbstractRenal fibrosis (RF) is the common pathway for a variety of chronic kidney diseases that progress to end-stage renal disease. Chitosan oligosaccharide (COS) has been identified as possessing many health functions. However, it is not clear whether COS can prevent RF. The purpose of this paper was to explore the action and mechanism of COS in alleviating RF. First, an acute unilateral ureteral obstruction operation (UUO) in male BALB/c mice was performed to induce RF, and COS or fosinopril (positive control drug) were administered for 7 consecutive days. Data from our experiments indicated that COS treatment can significantly alleviate kidney injury and decrease the levels of blood urea nitrogen (BUN) and serum creatinine (SCr) in the UUO mouse model. More importantly, our results show that COS can reduce collagen deposition and decrease the expression of fibrosis proteins, such as collagen IV, fibronectin, collagen I, α-smooth muscle actin (α-SMA) and E-cadherin, ameliorating experimental renal fibrosis in vivo. In addition, we also found that COS suppressed oxidative stress and inflammation in RF model mice. Further studies indicated that the mechanism by which COS alleviates renal fibrosis is closely related to the regulation of the TGF-β1/Smad pathway. COS has a therapeutic effect on ameliorating renal fibrosis similar to that of the positive control drug fosinopril. Taken together, COS can alleviate renal fibrosis induced by UUO by reducing oxidative stress damage and regulating the TGF-β1/Smad pathway.
Green enhancement of wood plastic composite based on agriculture wastes compatibility via fungal enzymes
Authors: Hasanin Mohamed S. , Abd El-Aziz Mahmoud E. , El-Nagar Islam , Hassan Youssef R. , Youssef Ahmed M. 
Published: November 2022

AbstractThis study deals with the production of natural fiber plastic composites (NFPCs) to reduce environmental pollution with agricultural and plastic waste. Where the NFPCs were prepared from waste/pure polyethylene (WPE) (pure polyethylene (50%)/recycled polyethylene (50%)) and modified sunflower waste via an eco-friendly and economic biological process. The sunflower fibers (SF) were treated via whole selective fungal isolate, namely,Rhizopus oryzae(acc no. OM912662) using two different incubation conditions; submerged (Sub), and solid-state fermentation (SSF) to enhance the fibers' compatibility with WPE. The treated and untreated fibers were added to WPE with various concentrations (10 and 20 wt%). The morphology and structure of fibers were characterised by a scanning electron microscope (SEM) and attenuated total reflection-Fourier transform infrared (ATR-FTIR). Furthermore, the mechanical properties, morphology, biodegradation and water vapour transmission rate (WVTR) for the prepared NFPCs were investigated. The results showed that compatibility, mechanical properties and biodegradation of NFPCs were improved by the addition of sunflower fibers treated by SSF conditions.
The role of preoperative albumin and white blood cell count in surgical site infections following whipple surgery
Authors: Tfaily Mohamad Ali , Ghanem Paola , Farran Sarah H. , Dabdoub Fatema , Kanafani Zeina A. 
Published: November 2022

AbstractWhipple surgery is associated with a high risk of surgical sites infections (SSIs). Nutritional deficiency has been associated with an increased risk of wound infections. This study aims at exploring the role of preoperative albumin levels in predicting the risk of SSIs following Whipple surgery. A total of 23,808 individuals were identified from the ACS-NSQIP database from years 2011 to 2017. The primary exposure was pre-operative albumin while the secondary exposure was white blood cell (WBC) count. The primary outcome was divided into superficial and deep surgical site infections (S/D SSI) and organ-space SSI. All statistical analyses were conducted using IBM Statistical Package for Social Sciences version 26. Levels of pre-operative serum albumin less than 3.73 g/L, dirty and contaminated wounds and longer operative time were associated with increased odds for developing S/D SSIs (OR = 1.14, OR = 1.17, OR = 1.06, respectively, p-value < 0.05). Pre-operative WBC level (/L) was associated with a risk of developing an organ-space SSI but not S/D SSI (OR = 1.02, p-value  0.003). This study demonstrates the predictive role of pre-operative albumin in developing S/D SSIs and highlights the need to develop therapeutic strategies to optimize the pre-operative nutritional health status of patients undergoing Whipple surgery.