bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pelatihan Kewirausahaan Melalui Pembuatan Strap Mask Bagi Warga Desa Sengguruh Kecamatan Kepanjen Kabupaten Malang
Authors: Pradani Yayi , Permadi Luchyto Chandra Permadi , Meditama Ratna Fajarwati , Putra Agus Dwi , Fitriani Indah Martha 
Published: April 2022

Kewirausahaan didasarkan dari proses berpikir seseorang. Proses berpikir dapat menghasilkan sesuatu yang mendorong munculnya proses kewirausahaan, yang dapat berupa ide, kreativitas, bahkan inovasi. Pelatihan kewirausahaan ini diharapkan mampu memberikan dampak positif kepada warga masyarakat ditengah pandemik yang belum berakhir. Secara umum pelatihan merupakan bagian dari pendidikan yang menggambarkan suatu proses dalam pengembangan organisasi maupun masyarakat. Salah satu dampak positif yang diharapkan adalah meningkatnya pendapatan warga melalui penjualan strap mask setelah dilaksanakannya pelatihan ini. Penggunaan strap mask atau tali masker menjadi marak di kalangan masyarakat. Lokasi kegiatan berada di RT. 23 RW. 03 Desa Sengguruh Kecamatan Kepanjen Kabupaten Malang. Kegiatan sosialisasi dilaksanakan selama 3 hari, pada 24-26 Januari 2022. Langkah awal yang dilakukan yaitu identifikasi masalah. Identifikasi masalah tersebut bertujuan untuk menganalisis kebutuhan masyarakat.Dari kegiatan pelatihan yang diberikan ini diharapkan mampu memberikan pendapatan tambahan di masa pandemi seperti sekarang ini.
Pelatihan Pemanfaatan Limbah Kulit Singkong Menjadi Keripik
Authors: Rustantono Hendra , Kusumaningrum Diana , Rasyid Hamidi 
Published: April 2022

Limbah kulit singkong yang biasa banyak dibuang begitu saja oleh masyarakat Dusun Klepu Desa Klepu Kecamatan Sumber Manjing Wetan Kabupaten Malang ternyata dapat dijadikan berbagai jajanan sehat untuk keluarga khususnya untuk anak-anaka. Kegiatan pengabdian pada masyarakat ini merupakan kegiatan berupa pelatihan cara mengolah limbah kulit ketela pohon menjadi bahan makanan yang sehat serta aman bagi masyarakat Dusun Klepu Desa Klepu Kecamatan Sumber Manjing Wetan Kabupaten Malang. Tujuannya adalah untuk memberikan pengetahuan dan pelatihan bagi masyarakat Dusun Klepu Desa Klepu Kecamatan Sumber Manjing Wetan Kabupaten Malang serta untuk mendorong motivasi dan kewirausahaan untuk usaha yang inovatif dan ekonomis untuk meningkatkan pendapatan rumah tangga warga Dusun Klepu Desa Klepu Kecamatan Sumber Manjing Wetan Kabupaten Malang. Metode yang digunakan dalam kegiatan ini terdiri dari empat tahap yaitu identifikasi masalah, sosialisasi di lapangan, persiapan, dan pelaksanaan pengolahan limbah kulit ketela pohon. Setelah mengolah hasil yang diperoleh pada kegiatan ini, kulit ketela pohon dapat diolah menjadi jajanan yang sehat dan aman, khususnya bagi anak-anak.
Live-Birth Prediction of Natural-Cycle In Vitro Fertilization Using 57,558 Linked Cycle Records: A Machine Learning Perspective
Authors: Zhang Yanran , Shen Lei , Yin Xinghui , Chen Wenfeng 
Published: April 2022

BackgroundNatural-cycle in vitro fertilization (NC-IVF) is an in vitro fertilization (IVF) cycle without gonadotropins or any other stimulation of follicular growth. Previous studies on live-birth prediction of NC-IVF were very few; the sample size was very limited. This study aims to construct a machine learning model to predict live-birth occurrence of NC-IVF using 57,558 linked cycle records and help clinicians develop treatment strategies.Design and MethodsThe dataset contained 57,558 anonymized register patient records undergoing NC-IVF cycles from 2005 to 2016 filtered from 7bsp;60,732 records in the Human Fertilisation and Embryology Authority (HFEA) data. We selected matching records and features through data filtering and feature selection methods. Two groups of twelve machine learning models were trained and tested. Eight metrics, e.g., F1 score, Matthews correlation coefficient (MCC), the area under the receiver operating characteristic curve (AUC), etc., were computed to evaluate the performance of each model.ResultsTwo groups of twelve models were trained and tested. The artificial neural network (ANN) model performed the best in the machine learning group (F1 score, 70.87%; MCC, 50.37%; and AUC score, 0.7939). The LogitBoost model obtained the best scores in the ensemble learning group (F1 score, 70.57%; MCC, 50.75%; and AUC score, 0.7907). After the comparison between the two models, the LogitBoost model was recognized as an optimal one.ConclusionIn this study, NC-IVF-related datasets were extracted from the HFEA data, and a machine learning-based prediction model was successfully constructed through this largest NC-IVF dataset currently. This model is universal and stable, which can help clinicians predict the live-birth success rate of NC-IVF in advance before developing IVF treatment strategies and then choose the best benefit treatment strategy according to the patients’ wishes. As “use less stimulation and back to natural condition” becomes more and more popular, this model is more meaningful in the decision-making assistance system for IVF.
Causal Association of Type 2 Diabetes Mellitus and Glycemic Traits With Cardiovascular Diseases and Lipid Traits: A Mendelian Randomization Study
Authors: Huang Mingkai , Laina-Nicaise Loum-Davadi , Zha Lingfeng , Tang Tingting , Cheng Xiang 
Published: April 2022

ObjectiveWe aimed to evaluate the causal effect of type 2 diabetes mellitus (T2DM) and glycemic traits on the risk of a wide range of cardiovascular diseases (CVDs) and lipid traits using Mendelian randomization (MR).MethodsGenetic variants associated with T2DM, fasting glucose, fasting insulin, and hemoglobin A1c were selected as instrumental variables to perform both univariable and multivariable MR analyses.ResultsIn univariable MR, genetically predicted T2DM was associated with higher odds of peripheral artery disease (pooled odds ratio (OR) =1.207, 95% CI: 1.162-1.254), myocardial infarction (OR =1.132, 95% CI: 1.104-1.160), ischemic heart disease (OR =1.129, 95% CI: 1.105-1.154), heart failure (OR =1.050, 95% CI: 1.029-1.072), stroke (OR =1.087, 95% CI: 1.068-1.107), ischemic stroke (OR =1.080, 95% CI: 1.059-1.102), essential hypertension (OR =1.013, 95% CI: 1.010-1.015), coronary atherosclerosis (OR =1.005, 95% CI: 1.004-1.007), and major coronary heart disease event (OR =1.003, 95% CI: 1.002-1.004). Additionally, T2DM was causally related to lower levels of high-density lipoprotein cholesterol (OR =0.965, 95% CI: 0.958-0.973) and apolipoprotein A (OR =0.982, 95% CI: 0.977-0.987) but a higher level of triglycerides (OR =1.060, 95% CI: 1.036-1.084). Moreover, causal effect of glycemic traits on CVDs and lipid traits were also observed. Finally, most results of univariable MR were supported by multivariable MR.ConclusionWe provided evidence for the causal effects of T2DM and glycemic traits on the risk of CVDs and dyslipidemia. Further investigations to elucidate the underlying mechanisms are warranted.
Mechanism of Abelmoschus manihot L. in the Treatment of Contrast-Induced Nephropathy on the Basis of Network Pharmacology Analysis
Authors: Xu Zhongchi , Qian Lichao , Niu Ruge , Wang Yibei , Yang Ying , Liu Chunling , Lin Xin 
Published: April 2022

BackgroundContrast-induced nephropathy (CIN) is increasingly seen in patients receiving contrast medium. Abelmoschus manihot (L.) Medik. (Malvaceae) and its preparations are widely used and effective in the treatment of various chronic kidney diseases and CIN in China. It is supposed to be an important adjuvant therapy for CIN.MethodsPubMed and CNKI were searched for the main compounds of A. manihot L. The Swiss target prediction platform, OMIM, GeneCards, DisGeNET, and DrugBank databases were mined for information relevant to the prediction of targets that A. manihot L. in the treatment of CIN. Subsequently, STRING database was applied for the construction of the PPI protein interaction network, meanwhile, the core targets were screened. DAVID database was used to perform the GO function and Kegg signal pathway enrichment analysis. AutoDockTools and PYMOAL were used for molecular docking. Vitro experiments were used to verify the effect of TFA, the main active component of A. manihot L., in the intervention of iopromide-induced cells injury.ResultsA total of 17 chemical components and 133 potential targets in A. manihot L. were obtained. The top 15 proteins with higher degree value were selected from the PPI network model, AKT1, PIK3R1, EGFR, SRC,AR, APP, TNF, GAPDH, MMP9, and PTPN1, etc. may be core targets. The enrichment analysis indicated that A. manihot L. was involved in the regulation of PI3K/AKT signaling pathway, FoxO signaling pathway, VEGF signaling pathway, HIF-1, TNF signaling pathway, melanoma, hepatitis B, and other signaling pathways which were mainly associated with the regulation of transcription and apoptosis, protein phosphorylation, inflammatory response, aging, and cell proliferation. Molecular docking indicated that the key components and core targets had a good binding ability. The vitro experiments illustrated that TFA reduces iopromide induced renal tubular cell injury and apoptosis, which may be related to regulating the phosphorylation of AKT.ConclusionThe study preliminarily revealed the multi-component, multi-target, and multi-pathway synergistic effects of A. manihot L. on CIN, which provide theoretical reference and basis for the study of the pharmacological mechanism of A. manihot L. in the treatment of CIN.
Student Counseling Centers in Europe: A Retrospective Analysis
Authors: Franzoi Isabella Giulia , Sauta Maria Domenica , Carnevale Giuliano , Granieri Antonella 
Published: April 2022

ObjectiveTertiary education can be stressful for many young people, who consistently report high levels of distress. The issue has major implications for campus health services and mental health policymaking more widely. The present study proposes to map student counseling services in Europe.MethodsThe sample of institutions was sourced, using standardized data extraction, from the European Tertiary Education Register (ETER). Then, each institution’s website was analyzed for information about the availability of student counseling centers and the services provided. Data extracted from the ETER database were: ETER ID, national identifier, institution name, English institution name, number of students, legal status (in English), institution category (in English), and institutional website. Data extracted from institutions’ websites concerned the availability of students’ psychological centers and the services provided. Analyses were carried out using the SPSS Statistics software package (IBM Corp., Armonk, NY, United States), version 26.ResultsOverall, it was found that most institutions do not provide mental health counseling services for their students. Institutions of medium dimensions showed a higher probability of reporting students’ psychological centers than small institutions. Moreover, private institutions and public institutions were more likely to report having such centers, while private government-dependent institutions were less likely. Universities of applied sciences and universities were more likely to report having them, while other institutions were less likely. Regarding provision according to geographic area, compared to Northern Europe, every other European region was less likely to report featuring such centers. Most institutions reported offering counseling, career counseling, or not otherwise specified psychological services, but only a small number reported providing services such as psychotherapy, psychiatric services, or counseling for learning-specific disabilities.ConclusionIt is critically important to catalog European data on student counseling centers and services, to encourage tertiary education institutions to invest in such services as key sites for mental health promotion. Indeed, professionally trained staff and the possibility of long-term treatment options would go a long way in supporting students who might not otherwise have access to treatment.
Is It a Gut Feeling? Bodily Sensations Associated With the Experience of Valence and Arousal in Patients With Inflammatory Bowel Disease
Authors: Atanasova Konstantina , Lotter Tobias , Bekrater-Bodmann Robin , Kleindienst Nikolaus , Reindl Wolfgang , Lis Stefanie 
Published: April 2022

BackgroundPrevious studies have shown dysfunctional emotion processing in patients with inflammatory bowel diseases (IBD), characterized by a hypersensitivity to negative emotions and a hyposensitivity to positive emotions. Models of emotion processing emphasize the importance of bodily sensations to the experience of emotions. Since there have been no studies on whether emotion-associated bodily sensations are changed in IBD, we investigated the experience of bodily sensations related to valence and arousal, together with their links to emotional awareness, as one domain of interoceptive sensibility relevant to emotion processing.MethodsUsing a topographical self-report measure, 41 IBD patients in clinical remission and 44 healthy control (HC) participants were asked to indicate where and how intensely in their body they perceive changes when experiencing emotions of positive and negative valence, as well as relaxation and tension. Additionally, we used self-report questionnaires to assess emotional awareness as one domain of an individual’s interoceptive sensibility, gastrointestinal-specific anxiety (GSA), and psychological distress.ResultsPatients with IBD reported higher emotional awareness but lower intensities of perceived changes in their bodily sensations related to valence and arousal of emotional processing. IBD patients reported less intense bodily activation during positive emotions and less intense bodily deactivation during negative emotional states in comparison to HC participants. Higher emotional awareness and psychological distress were linked to stronger experiences of emotion-related bodily sensations in IBD patients.ConclusionInflammatory bowel diseases patients exhibited alterations in how they link bodily sensations to their emotional experience. Such persistent changes can affect a patient’s wellbeing and are related to higher levels of anxiety and depression among IBD patients, even in remission.
ANALISIS PENGARUH ZAT POLIMER PAVING BLOCK FABA (FLY ASH & BOTTOM ASH) DENGAN VARIABEL SEMEN DAN FLY ASH PLTU TJB JEPARA
Authors: Rio Bobby , Hidayati Nor , Qomaruddin Mochammad , Ferdiasah FERI FIRMAN 
Published: April 2022

Penelitian ini dilatarbelakangi oleh rendahnya pemanfaatan limbah batu bara di PLTU Tanjung Jati B Jepara. Batu bara yang dimanfaatkan untuk sumber energi akan menghasilkan residu berupa fly ash dan bottom ash. Di Indonesia khususnya di Jepara banyak ditemukan fly ash dan bottom ash yang dimana jumlahnya akan bertambah setiap tahunnya bila tidak ditangani secara serius. Guna mengatasi hal itu maka dilakukan pengkajian untuk memanfaatkan limbah batu bara khususnya fly ash dan bottom ash. Dan salah satu cara pemanfaatan limbah tersebut adalah dengan menggunakan material fly ash dan bottom ash sebagai bahan pengganti sebagian semen dan agregat pada campuran pembuatan paving block. [1]Oleh karena itu, perlu dilakukan pengujian tentang pengaruh fly ash dan bottom ash sebagai pengganti sebagian semen dan agregat terhadap uji kuat tekan beton dan daya serap air pada paving block. Komposisi sudah ditentukan dengan perbandingan yaitu : A (PC 100% : FA 0%), B (PC 97% : FA 3%), C (PC94% : FA 6%), D (PC 91% : FA 9%), E (PC 88% : FA 12%), F (PC 85% : FA 15%) dengan keadaan BA (bottom ash) dengan keadaan konsisten menggunakan perbandingan dengan bindernya 3 : 1 masing-masing bottom ash : binder. Metode perbandingan komposisi campuran paving block diatur untuk mutu beton k 175 dan k 225 dengan memaksimalkan subtitusi fly ash dan bottom ash dalam campuran pembuatan paving block. Hasil yang didapatkan setelah melakukan pengujian selama 28 hari paving dengan menggunakan polimer 1% lebih tinggi dibandingkan dengan paving blok dengan kandungan polimer 2%. Sedangkan dalam perbandingan terhadap subtitusi FA terhadap PC mengalami penurunan setiap penambahan fly ash.
Relationship Pattern Of Working Parents To The Independence Of Toilet Training Pre School Children (Literature Study)
Authors: Rahayu Suci Fitri 
Published: April 2022

The success of toilet training occurs because there are many factors including age, sex, culture, parents' motivation, children's readiness physically, psychologically and intellectually. In addition, one of the important factors for the success of toilet training is the parenting style applied by parents in educating their children at home. This study aims to determine the relationship between working parents' parenting styles and children's independence in toilet training. In this study, a literature study was used by analyzing 5 national journals and 2 international journals. This research study is a type of literature study research by looking for theoretical references that are relevant to the cases or problems found. Based on the results of the analysis of several journals above, there are many who say that the parenting style of working parents is related to children's independence in toelite trening. The results of the research can be used as material to evaluate and prepare health promotion strategies for health workers, especially nurses, in increasing the knowledge and attitudes of parents, especially parents who work outside the home to apply parenting to pre-school children (3 - 5 years) according to the child's personality development.
Keywords: parenting style, toilet training
Effect of Concentrations of Basil Seed Gum on the Sensory Properties of Chicken Sausage
Authors: A. A. Abdulrahem Batool , M. K. Al-Aubadi Inas , M. A. Mohamed Mahmoud 
Published: April 2022

Chicken meat is a low-fat, high-protein food that is increasingly growing in popularity around the world. Therefore, various food ingredients have been added to improve the characteristics of the chicken sausage. Among them, Basil seed gum (BSG) was extracted, and the effect of adding it in percentages of 0.5, 1.0, 1.5, and 2.0 % was studied as- a partial replacement- for animal fat in processed sausages and its effect on the proximate composition, sensory and quality characteristics of chicken sausages. The yield of gum extract was 17.5% on a dry-weight basis. Moreover, the results of analyzing the proximate composition of prepared sausage showed an increase in the moisture, protein, and ash percentage. However, the percentage of fat, carbohydrates, and caloric value in them decreased. The results also showed increased water holding capacity, emulsion stability, and cooking yield in the prepared sausages. In contrast, the percentage of cooking loss and loss of thaw loss decreased. It was also noted that the peroxide value, free fatty acids, and cholesterol decreased by increasing the concentration of gum added, up to 2%. Besides that, the addition of gum concentrations resulted in a clear improvement in the sensory characteristics and acceptability of the assessor, especially colour, tenderness, juiciness, and overall acceptability. It can be concluded from this research that the possibility of using BSG as a fat replacer to manufacture low-fat chicken sausages, which contributes to reducing the cost of sausage mixtures and giving a healthy, low-calorie product.
Learning Mindset In Today's Business: Leading To Innovation And Consumer-Centrix Motives
Authors: Wangsa Ign Heri Satrya 
Published: April 2022

Innovation has become relevant keywords for business that may intend to be competitive as there will be a creation of new breakthrough which has the orientation to form consumer-centrix motives. Innovative business could label consurner-centrix touch toward its products. Old result­oriented mindset will then go through how to ideally accomplish consumer's expectation. The growing number of various customized products or tailor-made products has brought an important indication that consumer has become major issue. Innovative activities could not be continuously applied unless the business has mindset to renew its cycle. As an organism, a business should have learning mindset which could motivate itself to keep innovative. This is an introductory paper which hopefully facilitates those who want to conduct thorough srudy related to learning mindset on innovation and consumer-centrix motives.
Conceptualizing Human Capital As A Free-Exploitation Instrument In Economic Development
Authors: Wangsa Ign Heri Satrya 
Published: April 2022

Human capital with in the context of economic development means efforts to revitalize meaning of development which is more on developing economic capacity for human within the concept of homo economicus. It means that, the appropriate meaning of economic development is to replace pt of human as an economic man who is free from exploitation. Economic development should be directed at human as potential resources which contribute to productivity. Therefore, within the context of economic development, the concept of homo economicus should be clearly defined as human who recognizes himself consciously as economic man and economic instrument as well. Consequently, it is necessaery to create and develop economic values potensials to increase productivity. Process of human capital accumulation which consciously accomplished has placed human as subject in economic development. Facts of capitalism has reduced and minimized human as resources that run a risk of exploitation. The human dimension in economic development should be directed to the concept of homo economicus perceived as “human who is completely conscious” and a free-exploitation resources.
Faktor-Faktor Yang Berpengaruh Terhadap Kepatuhan Pembayaran Pajak
Authors: Purnomolastu N. 
Published: April 2022

Tax is Indonesian country main source which should be increased in income. In order to increase the income in tax field, so the effort done by the government is by improving taxpayer obedience. The taxpayer obedience about tax payment needs to be improved continually, remembering the comparation ratio of tax income total and gross domestic product that is also called as tax ratio is still low. Indonesian Tax Ratio about 12% is still far from the hoped. The efforts for improving taxpayer obedience continue to be done by the government, i.e. through several ways. They are improving tax socialization by various kinds of campaign, improving service toward taxpayer through prime service and law enforcementtoward taxpayer through taxation sanctions. In this research, the writer expresses the socialization factor influences, law service and enforcement toward the obedience level of taxpayer payment. The obedience itself can characterize as formal, i.e. the obedience in delivering reports and material obedience, it is the paid nominal amounts.