bluuebunny/crossref_metadata_2025_split huggingface dataset:
Loss of Neurodevelopmental Gene CASK Disrupts Neural Connectivity in Human Cortical Excitatory Neurons
Authors: McSweeney Danny , Gabriel Rafael , Jin Kang , Pang Zhiping P. , Aronow Bruce , Pak ChangHui 
Published: February 2022

SummaryLoss-of-function (LOF) mutations in CASK cause severe developmental phenotypes, including microcephaly with pontine and cerebellar hypoplasia, X-linked intellectual disability, and autism. Unraveling the pathogenesis of CASK-related disorders has been challenging due to limited human cellular models to study the dynamic roles of this molecule during neuronal and synapse development. Here, we generated CASK knockout (KO) isogenic cell lines from human embryonic stem cells (hESCs) using CRISPR/Cas9 and examined gene expression, morphometrics, and synaptic function of induced neuronal cells during development. While young (immature) CASK KO neurons show robust neuronal outgrowth, mature CASK KO neurons displayed severe defects in synaptic transmission and synchronized burst activity without compromising neuronal morphology and synapse numbers. In developing human cortical neurons, CASK functioned to promote both structural integrity and establishment of cortical excitatory neuronal networks. These results lay the foundation for future studies to identify suppressors of such phenotypes relevant to human patients.HighlightsCASK LOF mutations increase neuronal complexity in immature developing neuronsCASK LOF does not alter synapse formation and neurite complexity in mature neuronsSynaptic transmission and network synchronicity are compromised in CASK KO neuronsDifferential gene expression analysis reveals enrichment of synaptic gene networks in mature CASK KO neurons
Neural correlates of multisensory enhancement in audiovisual narrative speech perception: a fMRI investigation
Authors: Ross Lars A. , Molholm Sophie , Butler John S. , Del Bene Victor A. , Foxe John J. 
Published: February 2022

ABSTRACTThis fMRI study investigated the effect of seeing articulatory movements of a speaker while listening to a naturalistic narrative stimulus. It had the goal to identify regions of the language network showing multisensory enhancement under synchronous audiovisual conditions. We expected this enhancement to emerge in regions known to underlie the integration of auditory and visual information such as the posterior superior temporal gyrus as well as parts of the broader language network, including the semantic system. To this end we presented 53 participants with a continuous narration of a story in auditory alone, visual alone, and both synchronous and asynchronous audiovisual speech conditions while recording brain activity using BOLD fMRI. We found multisensory enhancement in an extensive network of regions underlying multisensory integration and parts of the semantic network as well as extralinguistic regions not usually associated with multisensory integration, namely the primary visual cortex and the bilateral amygdala. Analysis also revealed involvement of thalamic brain regions along the visual and auditory pathways more commonly associated with early sensory processing. We conclude that under natural listening conditions, multisensory enhancement not only involves sites of multisensory integration but many regions of the wider semantic network and includes regions associated with extralinguistic sensory, perceptual and cognitive processing.
Investigation of electromagnetic wave propagation in the bicomplex 3D-FEM using a wavenumber Whitney Hodge operator
Authors: Reum Thomas , Toepfer Hannes 
Published: February 2022

Purpose
The purpose of this paper is to show the applicability of a discrete Hodge operator in the context of the De Rham cohomology to bicomplex-valued electromagnetic wave propagation problems. It was applied in the finite element method (FEM) to get a higher accuracy through conformal discretization. Therewith, merely the primal mesh is needed to discretize the full system of Maxwell equations.

Design/methodology/approach
At the beginning, the theoretical background is presented. The bicomplex number system is used as a geometrical algebra to describe three-dimensional electromagnetic problems. Because we treat rotational field problems, Whitney edge elements are chosen in the FEM to realize a conformal discretization. Next, numerical simulations regarding practical wave propagation problems are performed and compared with the common FEM approach using the Helmholtz equation.

Findings
Different field problems of three-dimensional electromagnetic wave propagation are treated to present the merits and shortcomings of the method, which calculates the electric and magnetic field at the same spatial location on a primal mesh. A significant improvement in accuracy is achieved, whereas fewer essential boundary conditions are necessary. Furthermore, no numerical dispersion is observed.

Originality/value
A novel Hodge operator, which acts on bicomplex-valued cotangential spaces, is constructed and discretized as an edge-based finite element matrix. The interpretation of the proposed geometrical algebra in the language of the De Rham cohomology leads to a more comprehensive viewpoint than the classical treatment in FEM. The presented paper may motivate researchers to interpret the form of number system as a degree of freedom when modeling physical effects. Several relationships between physical quantities might be inherently implemented in such an algebra.
Measurement and modeling of effective cable parameters of unshielded conductors
Authors: Hollaus Karl , Bauer Susanne , Leumüller Michael , Türk Christian 
Published: February 2022

Purpose
Cables are ubiquitous in electronic-based systems. Electromagnetic emission of cables and crosstalk between wires is an important issue in electromagnetic compatibility and is to be minimized in the design phase. To facilitate the design, models of different complexity and accuracy, for instance, circuit models or finite element (FE) simulations, are used. The purpose of this study is to compare transmission line parameters obtained by measurements and simulations.

Design/methodology/approach
Transmission line parameters were determined by means of measurements in the frequency and time domain and by FE simulations in the frequency domain and compared. Finally, a Spice simulation with lumped elements was performed.

Findings
The determination of the effective permittivity of insulated wires seems to be a key issue in comparing measurements and simulations.

Originality/value
A space decomposition technique for a guided wave on an infinite configuration with constant cross-section has been introduced, where an analytic representation in the direction of propagation is used, and the transversal fields are approximated by FEs.
Simulation of heat and fluid flow in porous medium and fractures by material point method
Authors: Wang Guilin , Sun Fan , Wang Runqiu , Zhang Liang , Cao Tianci , Li Boyi 
Published: February 2022

Purpose
The material point method (MPM)is a particle-based numerical method suitable for solid–liquid simulation and large deformation problems. However, MPM is generally used in solid deformation at present, to develop a multi-physics coupling MPM; the purpose of this study is to extend the MPM to simulate the heat and fluid flow and address the thermal-hydrological (TH) coupling problems.

Design/methodology/approach
The porous medium was discretized into two sets of Lagrangian points, and the motion of fluid points follows the Darcy’s law. Two sets of heat transport equations were established for the heat conduction and heat exchange in the pore fluid and solid skeleton. Fractures were considered by adding the porosity gradient term in the governing equations; also a transition function was introduced to smoothen the fracture boundary.

Findings
Four cases of heat and fluid flow in porous medium and fractures were presented to verify the feasibility of the proposed method. And the effects of fractures on heat and fluid flow were investigated. Additionally, a case of geothermal extraction was solved and the importance of the interstitial convective heat transfer coefficient was analyzed.

Originality/value
The proposed method extends the conventional MPM, using two sets of material points and two sets of heat transport equations to simulate the heat and fluid flow and address the TH coupling problems, which can be applied in both porous medium and fractures.
Using hotel reviews to assess hotel frontline employees’ roles and performances
Authors: Hu Feng , Trivedi Rohit , Teichert Thorsten 
Published: February 2022

Purpose
This study aims to explore how marketers can use text mining to analyze actors, actions and performance effects of service encounters by building on the role theory. This enables hotel managers to use introduced methodology to measure and monitor frontline employees’ role behavior and optimize their service.

Design/methodology/approach
The authors’ approach links text mining and importance-performance analysis with role theory’s conceptual foundations taking into account the hotel industry’s specifics to assess the effect of frontline hotel employees’ actions on consumer satisfaction and to derive specific management implications for the hospitality sector.

Findings
This study identifies different actors involved in hotel frontline interactions revealing distinct role behaviors that characterize consumers’ perspectives of service encounters with different role types associated with front-office employees. This research also identifies role performance related to role behavior to improve service encounters.

Practical implications
Customer–employee interactions can be assessed by user-generated contents (UGC). Performance evaluations relate to frontline employee roles associated with distinct role scripts, whereby different hotel segments require tailored role designs. Insights of this study can be used for service optimization, market positioning as well as for improving human resource management practices in the hotel industry.

Originality/value
This study contributes to the service encounter literature by applying role theory in the text mining of UGC to assess frontline employees as actors and the effects of their actions on service quality delivery.
Empowering undergraduate students to take action: an empathetic mindset toward education for sustainable development
Authors: Lin Chi-I , Li Yuh-Yuh 
Published: February 2022

Purpose
This study aims to investigate the potential of an empathetic mindset aimed at empowering undergraduate students to work toward sustainable development (SD), addressing both theoretical and practical dimensions.

Design/methodology/approach
A mixed quantitative and qualitative research method was used in this study. Cross-sectional quantitative survey data on students’ mindsets and actions toward SD was collected to examine the theoretical relationship between belief and behavior. Qualitative inquiry using focus-group interviews explored students’ on-site learning experiences.

Findings
This study provides evidence for the impact of an empathetic mindset on education for sustainable development (ESD). Results showed that students with a more empathetic mindset showed better attitudes and behaviors toward SD actions. Findings suggest that developing an empathetic mindset improves students’ attitudes toward taking substantial action to protect the environment.

Originality/value
This study introduces a novel perspective extending the application of empathetic mindset in ESD.
High-contact services of the transient and high-uncertainty type: managing customer experience
Authors: Yee Rachel W.Y. , Choi Thomas Y. , Yeung Andy C.L. , Cheng T.C.E. 
Published: February 2022

PurposeMany small-to-medium sized service shops (e.g. jewelry shops, fine-dining restaurants etc.) operate in a unique service environment. They often face customers in transit (i.e. transient delivery) and with minimal information of their preferences (i.e. high uncertainty). This study investigates how such shops create service experience to customers by focusing on three constructs, namely, customer orientation, management commitment to service quality and quality of leader-member exchange in service systems with the uncertain and transient nature. Building on a systems approach of service experience design, the authors examine all possible effects (main effects and two-way and three-way interaction effects) on customer experience. Specifically, to frame the two-way and the three-way interaction effects, the authors adopt the contingency and configuration approaches, respectively.Design/methodology/approachThis study employs a multiple respondent approach involving managers, employees and customers to collect data from 225 service shops in Hong Kong. Hierarchically moderated regression analysis is employed to analyze the collected data.FindingsContrary to our initial conceptualization, most of the direct effects and two-way interaction effects among the three constructs are insignificant. The authors do, however, uncover a significant effect of the three-way interaction term. The authors analyze the results from the configuration perspective.Originality/valueThe finding suggests that the configuration approach is necessary to determine the configuration concerning how design elements align with one another to generate an integrative effect on customer experience. The authors conclude that for high-contact services of the transient and high-uncertainty type, all three constructs must operate simultaneously to evoke favorable customer experience. Customer experience is holistically developed in a service system with high-uncertainty and transient nature, requiring simultaneous alignment across a range of design choices among those involved in service delivery (manager, employee and customer).
Credit rating announcement and bond liquidity: the case of emerging bond markets
Authors: Saadaoui Amir , Elammari Anis , Kriaa Mohamed 
Published: February 2022

PurposeThis study examines the effect of the informational content of local credit rating announcements in emerging markets on the liquidity of their bond markets. This study analyses the liquidity of bonds in various emerging bond markets using a sample of nine countries: Argentina, Mexico, Peru, Hungary, Poland, Spain, Turkey, Hong Kong and Greece. The sample includes daily data on sovereign bonds that go from July 2009 to July 2017. The main focus is on the period before and after the sovereign debt crisis. This study notes that the bond liquidity is affected due to the sign of the rating granted by the rating agencies for each country.Design/methodology/approachThis study aims to question the sources of liquidity problem of sovereign bonds issued by the emerging countries. The study’s database consists of daily data of all nine emerging countries for the period from July 2009 to July 2017. Panel data were collected from the Datastream database.FindingsThis study first directly tests the information content of bond ratings announcements and their effect on bond market liquidity. Next, the impact of rating changes on sovereign bond liquidity around the rating announcements is studied. Rating changes can affect sovereign bond's price, trading and liquidity around the announcement date. In particular the rating changes that move the bonds out of the investment grade category can elicit selling pressure or even fire sale of the fallen angels.Originality/valueThis research aims to present data on the prices of sovereign bonds that react to changes in credit rating by studying the price movements around the announcement of changes in credit rating. The literature is very rich in studies on credit rating changes on stocks and corporate bonds, but this study is perhaps the first attempt on sovereign bonds.
Exploring British advertising and marketing history through records of The National Archives of the UK
Authors: Howells Katherine Margaret 
Published: February 2022

Purpose
This paper aims to showcase the range of historical records held at The National Archives of the UK which are potentially highly useful to researchers in marketing and advertising history, but have so far been under-appreciated in these fields.

Design/methodology/approach
By taking key record collections, primarily intellectual property records and records of government publicity, and examining them from the perspective of different fields of study, the potential of these collections is brought to light. This paper also draws out key examples of past research with these collections to show both the effectiveness of these records as sources for research and at the same time the limited way they have so far been approached by academics.

Findings
This review of the records demonstrates how researchers working in advertising and marketing history fields might supplement their research or open up new research avenues with the benefit of new sources. It shows how assumptions about government archives need to be reconsidered to avoid missing research opportunities.

Practical implications
Sharing knowledge and increasing connections between government archives and academics in these fields may encourage archives to improve their own approaches to archival practice and academic engagement, to make records more accessible to these new research audiences. This would of course be beneficial both to researchers and government archives.

Originality/value
This paper provides a detailed examination of government records in the specific context of the field of marketing history. This unique focus makes a valuable contribution to the literature exploring historical sources for this field.
Viewpoint: shaping resilient service ecosystems in times of crises – a trans-Tasman perspective
Authors: Fehrer Julia A. , Bove Liliana L. 
Published: February 2022

Purpose
The purpose of this paper is to develop a holistic understanding for the shaping of resilient service ecosystems that considers tactics that act as stabilizing forces, and tactics that promote diversity and change and act as destabilizing forces – both central for service ecosystems to bounce forward in times of crises and beyond.

Design/methodology/approach
This conceptual paper draws on theory on complex adaptive service ecosystems and work on organizational resilience and resilient systems. With a focus on Australia and New Zealand, stalwarts of the top three economies in Bloomberg’s COVID Resilience Ranking before the arrival of the Delta variant, this study illustrates how resilient service ecosystems can be shaped.

Findings
This study explicates complexity related to navigating service ecosystems toward a new order in response to the pressures of major crises. It points to the importance of understanding both, how service ecosystems stabilize and change over time. It documents a portfolio of tactics that service organizations can use to influence resilience in the service ecosystems of which they are part. It further reflects on the potential downside of resilient service ecosystems, as they tilt toward rigid structures, failure to learn and an inability to transform or alternatively chaos.

Originality/value
Service research has made progress in explicating how a service ecosystems perspective can inform crises management. This paper extends this work and explains how service ecosystems can be shaped to bounce not only back from the imposed pressures of a disruptive event but also forward toward a new order.
Thermal properties of woven fabric as a function of its structural parameters: experimentation and modeling
Authors: Umair Muhammad , Javaid Muhammad Usman , Nawab Yasir , Jabbar Madeha , Riaz Shagufta , Abid Hafiz Affan , Shaker Khubab 
Published: February 2022

PurposeThis paper aims to investigate the influence of picking sequence, weave design and weft yarn material on the thermal conductivity of the woven fabrics.Design/methodology/approachThis work includes the development of 36 woven samples with two weave designs (1/1 plain and 3/1 twill), three picking sequences (single, double and three pick insertion) and six different weft yarn materials (cotton, polyester having 48 filaments, polyester with 144 filaments, spun coolmax having Lycra in core and coolmax in sheath, filament coolmax and polypropylene). The thermal conductivity was measured using ALAMBETA tester.FindingsThe results showed that weft yarn material, weave design and picking sequence have a meaningful impact on the thermal conductivity of woven fabric. The value of thermal conductivity was lowest for the fabrics with three pick insertion and 3/1 twill weave in all weft yarn materials.Research limitations/implicationsPlain woven fabric with single pick insertion is feasible for summer wear to enhance the comfort of wearer. By changing the warp yarn grouping and material, improved thermal conductivity/resistance can also be achieved.Originality/valueThe authors have studied the combined effect of different weft yarn materials with different picking sequences and different weave designs on thermal conductivity of the woven fabrics.
The moderating effect of communication on congruence and incongruence of openness to change: is communication always beneficial for learning organization culture and knowledge sharing?
Authors: Koo Yohan , Kim Soo Jung , Song Ji Hoon 
Published: February 2022

Purpose
The purpose of this study was to explore the moderating role of communication in the relationship between person-organization fit (P-O fit) of openness to change, learning organization and knowledge sharing.

Design/methodology/approach
A total of 1,015 faculty and staff participants from three private universities in South Korea was included in the analysis. Individual and organizational aspects of openness to change were examined based on the P-O fit theory. Moderated polynomial regression and response surface methodology were used for data analysis.

Findings
At a higher level of communication, the congruence of openness to change between the individual and organization showed a positive fit effect on learning organization. The incongruence of openness to change between individual and organization, in which the organizations’ openness to change was higher than that of individuals, decreased the level of knowledge sharing when the level of communication was higher.

Originality/value
The results of this study support the theory and practice that consideration of P-O fit on openness to change and a strategic approach of communication are needed to succeed in organizational change.
Continuous veno‐venous hemodiafiltration in neonates with maple syrup urine disease
Authors: Deger İbrahim , Çelik Muhittin , Taş İbrahim , Samancı Serhat 
Published: February 2022

AbstractIntroductionHerein, we aimed to discuss our experience in 16 newborn patients with Maple syrup urine disease (MSUD) who were treated with urgent renal replacement therapy (RRT).MethodsThe patients underwent continuous veno‐venous hemodiafiltration (CVVHDF) or peritoneal dialysis (PD) as renal replacement therapy.ResultsEleven (68.75%) patients underwent CVVHDF and five (31.25%) underwent peritoneal dialysis. The median leucine reduction rate per hour was 2.56% (1.75–7.6) in the CVVHDF group, 0.78% (0.54–1.83) in the PD group, and was significantly higher in the CVVHDF group (p = 0.001). Posttreatment plasma leucine levels were found to be 198 (20–721) μmol/L in the CVVHDF group and 600 (250–967) μmol/L in the PD group, and CVVHDF was found to be significantly lower (p = 0.08). Complications such as hypotension, electrolyte imbalance, and filter obstruction occurred in the CVVHDF group.ConclusionThis study showed that CVVHDF is more effective than PD for rapidly eliminating elevated leucine levels caused by MSUD in the newborn and it is not associated with increased complication rates.