bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antenatal couples’ counselling in Uganda (ACCU): study protocol for a randomised controlled feasibility trial
Authors: Mubangizi Vincent , McGrath Nuala , Kabakyenga Jerome Kahuma , Muller Ingrid , Stuart Beth L. , Raftery James P. , Natukunda Sylvia , Ngonzi Joseph , Goodhart Clare , Willcox Merlin Luke 
Published: April 2022

AbstractBackgroundCommon avoidable factors leading to maternal, perinatal and neonatal deaths include lack of birth planning (and delivery in an inappropriate place) and unmet need for contraception. Progress has been slow because routine antenatal care has focused only on women. Yet, in Uganda, many women first want the approval of their husbands. The World Health Organization recommends postpartum family planning (PPFP) as a critical component of health care. The aim of this trial is to test the feasibility of recruiting and retaining participants in a trial of a complex community-based intervention to provide counselling to antenatal couples in Uganda.MethodsThis is a two-group, non-blinded cluster-randomised controlled feasibility trial of a complex intervention. Primary health centres in Uganda will be randomised to receive the intervention or usual care provided by the Ministry of Health. The intervention consists of training village health teams to provide basic counselling to couples at home, encouraging men to accompany their wives to an antenatal clinic, and secondly of training health workers to provide information and counselling to couples at antenatal clinics, to facilitate shared decision-making on the most appropriate place of delivery, and postpartum contraception. We aim to recruit 2 health centres in each arm, each with 10 village health teams, each of whom will aim to recruit 35 pregnant women (a total of 700 women per arm). The village health teams will follow up and collect data on pregnant women in the community up to 12 months after delivery and will directly enter the data using the COSMOS software on a smartphone.DiscussionThis intervention addresses two key avoidable factors in maternal, perinatal and neonatal deaths (lack of family planning and inappropriate place of delivery). Determining the acceptability and feasibility of antenatal couples’ counselling in this study will inform the design of a fully randomised controlled clinical trial. If this trial demonstrates the feasibility of recruitment and delivery, we will seek funding to conduct a fully powered trial of the complex intervention for improving uptake of birth planning and postpartum family planning in Uganda.Trial registrationPan African Clinical Trials RegistryPACTR202102794681952. Approved on 10 February 2021. ISRCTN Registry ISRCTN97229911. Registered on 23 September 2021
Feasibility of video recording interpersonal interactions between patients and hospital staff during usual care
Authors: Todd Angela L. , Roberts Lynette , Foster Kirsty 
Published: April 2022

Abstract
Background
Video-reflexive ethnography (VRE) has been used to record aspects of patient care which are then shared with staff to drive self-identified improvements. Interpersonal interactions between patients and hospital staff are key to high-quality, patient-centred care and mostly occur randomly throughout a patient’s hospital stay. One of the most common types of hospital admission is for women giving birth.

Aims
To assess the feasibility of adapting the VRE methodology to capture naturally occurring interactions between patients and health staff over an extended period during hospital admission, and to assess whether the approach would yield useful interaction data.

Participants
Twelve women, who had a planned caesarean section at 37+ weeks, were considered low risk (no known medical or obstetric complication) and were admitted to a postnatal unit after giving birth, and the staff who attended them.

Methods
This study took place in a large hospital in Sydney, Australia, where approximately 2200 women give birth each year. Continuous unattended video recordings were made during each woman’s hospital stay to capture interactions with hospital staff. The recordings were reviewed to determine what kinds of interaction data could be obtained.

Results
In order to recruit 12 eligible women, we needed to invite 45 to participate. The estimated recruitment period of 3–4 months had to be extended to 8 months. A fixed video camera was successfully installed in the hospital room of each woman and a remote control provided. A total of 246.5 h of video recordings was obtained, of which 38 h (15.5%) involved interpersonal interactions with staff. Two women reported negative responses from staff about being video recorded. Both quantitative and qualitative data could be obtained from the recordings.

Conclusion
Video recordings of interpersonal interactions between patients and staff in an in patient hospital care setting can be obtained and can provide unique insights into the complexity of healthcare delivery. However, significant contextual barriers can exist to engaging staff in quality improvement initiatives that are not part of their usual healthcare activities.
Suubi4Stigma study protocol: a pilot cluster randomized controlled trial to address HIV-associated stigma among adolescents living with HIV in Uganda
Authors: Nabunya Proscovia , Ssewamala Fred M. , Bahar Ozge Sensoy , Michalopoulos Lynn T. M. , Mugisha James , Neilands Torsten B. , Trani Jean-Francois , McKay Mary M. 
Published: April 2022

Abstract
Background
Sub-Saharan Africa (SSA) is heavily burdened by HIV, with 85% of the global new infections among adolescents happening in the region. With advances in medication and national policies promoting antiretroviral therapy (ART), children < 15 years living with HIV (CLWH) continue to grow with a chronic, highly stigmatized disease. Unfortunately, the stigma they experience results in much lower quality of life, including poor mental health and treatment outcomes. Family members also experience stigma and shame by virtue of their association with an HIV-infected family member. Yet, stigma-reduction interventions targeting CLWH and their families are very limited. The goal of this study is to address HIV-associated stigma among CLWH and their caregivers in Uganda.

Methods
This three-arm cluster randomized control trial, known as Suubi4Stigma, will evaluate the feasibility, acceptability, and preliminary impact of two evidence-based interventions: (1) group cognitive behavioral therapy (G-CBT) focused on cognitive restructuring and strengthening coping skills at the individual level and (2) a multiple family group (MFG) intervention that strengthens family relationships to address stigma among CLWH (N = 90, 10–14 years) and their families (dyads) in Uganda. Nine clinics will be randomized to one of three study arms (n = 3 clinics, 30 child-caregiver dyads each): (1) usual care; (2) G-CBT + usual care; and (3) MFG + usual care. Both treatment and control conditions will be delivered over a 3-month period. Data will be collected at baseline (pre-intervention) and at 3 months and 6 months post-intervention initiation.

Conclusion
The primary aim of the proposed project is to address the urgent need for theoretically and empirically informed interventions that seek to reduce HIV-associated stigma and its negative impact on adolescent health and psychosocial well-being. As several countries in SSA grapple with care and support for CLWH, this study will lay the foundation for a larger intervention study investigating how HIV-associated stigma can be reduced to foster healthy child development—especially for CLWH as they transition through adolescence.

Trial registration
ClinicalTrials.gov: NCT04528732; Registered August 27, 2020
Tunable narrow-band single-channel add-drop integrated optical filter with ultrawide FSR
Authors: Sun Chunlei , Yin Yuexin , Chen Zequn , Ye Yuting , Luo Ye , Ma Hui , Wang Lichun , Wei Maoliang , Jian Jialing , Tang Renjie , Dai Hao , Wu Jianghong , Li Junying , Zhang Daming , Lin Hongtao , Li Lan 
Published: April 2022

AbstractFree-spectral-range (FSR)-free optical filters have always been a critical challenge for photonic integrated circuits. A high-performance FSR-free filter is highly desired for communication, spectroscopy, and sensing applications. Despite significant progress in integrated optical filters, the FSR-free filter with a tunable narrow-band, high out-of-band rejection, and large fabrication tolerance has rarely been demonstrated. In this paper, we propose an exact and robust design method for add-drop filters (ADFs) with an FSR-free operation capability, a sub-nanometer optical bandwidth, and a high out-of-band rejection (OBR) ratio. The achieved filter has a 3-dB bandwidth of < 0.5 nm and an OBR ratio of 21.5 dB within a large waveband of 220 nm, which to the best of our knowledge, is the largest-FSR ADF demonstrated on a silicon photonic platform. The filter exhibits large tunability of 12.3 nm with a heating efficiency of 97 pm/mW and maintains the FSR-free feature in the whole tuning process. In addition, we fabricated a series of ADFs with different periods, which all showed reliable and excellent performances.
Association of high Body Mass Index and postdates pregnancy
Authors: Qazi Qudsia , Liaqat Nazia , Hussain Shehzadi Saima , Syed Wajeeha 
Published: April 2022

Background and Objective: Obesity with its growing prevalence is a major public health problem influencing gestational age at delivery. Raised Body Mass Index (BMI) has been shown to be associated with significantly increased risk of prolonged pregnancy; which is an important contributor to perinatal morbidity and mortality. Obesity needs modified antenatal, intrapartum and postpartum care by obstetrician. Limited data is found regarding association of obesity with prolonged pregnancy and the same fact led us to search for this association.
Methods: This cohort study was carried out in Gynecology and Obstetrics department, MTI Lady Reading Hospital Peshawar from March 2020 to April 2021. Patients were enrolled in third trimester at 37 weeks of gestation with primary exposures of interest being either self-reported pre-pregnancy weight or obtained from first trimester antenatal record. Patients were divided into two classes based on BMI i.e., one with BMI <25 and other with BMI ≥ 25. Patients in both classes were followed till their delivery to determine outcome of gestational age at delivery.
Results: Statistically significant difference between the two groups was seen at lower age range of 18-21 years(p-0.04) and higher age range of 39-42 years (p-0.0001). Statistically significant association was found between high pre pregnancy BMI and postdates pregnancy (OR:4.93 ;95%CI:1.98-12.26, p-0.001). Association of induction of labor with high pre pregnancy BMI was not significant. (OR 0.56, 95%CI:0.21-1.48, P < 0.001). Higher rates of Instrumental deliveries(p-0.0005) and cesarean sections (p-0.0001) were seen in higher BMI group.
Conclusion: Higher pre-pregnancy BMI is associated with increased risk of postdates pregnancy.
doi: https://doi.org/10.12669/pjms.38.5.4815
How to cite this:Qazi Q, Liaqat N, Hussain SS, Syed W. Association of high Body Mass Index and postdates pregnancy. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.4815
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Efficacy and Safety of N-Butyl 2 Cyanoacrylate Injection for Treatment of Gastric Varices: A five year experience from a tertiary care hospital in Karachi, Pakistan
Authors: Butt Nazish , Haleem Farhan , Khan Muhammad Ali , Abbasi Amanullah 
Published: April 2022

Objectives: To evaluate the efficacy and safety of N-Butyl 2 Cyanoacrylate injection for treatment of gastric varices.
Methods: This was a retrospective observational cohort conducted at Medical Unit IV, Department of Gastroenterology, JPMC, Karachi from January 2014 to December 2018 (five years). All patients irrespective of age and gender that presented to the emergency department with complain of hematemesis or stigmata of UGIB were potential candidates. Once they were resuscitated and endoscopic evidence of gastric varices requiring intervention was found, the patients were inducted into the study. N-Butyl 2 Cyanoacrylate injection was performed until hemostasis and obliteration of gastric varices was achieved. Response to therapy was analyzed at three weeks with repeat endoscopy. Mortality was analyzed at six weeks. Major and minor complications recorded as well.
Results: A total of 159 patients were inducted into the study. Isolated gastric varices Type-I was mostly encountered. A singular session was sufficient to achieve obliteration and hemostasis in over three quarter of the patients. Complications affected 11.30% of the patients. Six weeks mortality was exceptionally low at 1.20%.
Conclusions: N-Butyl 2 Cyanoacrylate is safe and effective for treatment of gastric varices. There were few complications seen with this procedure in this study. It significantly reduces mortality at six weeks.
doi: https://doi.org/10.12669/pjms.38.5.4999
How to cite this:Butt N, Haleem F, Khan MA, Abbasi A. Efficacy and Safety of N-Butyl 2 Cyanoacrylate Injection for Treatment of Gastric Varices: A five year experience from a tertiary care hospital in Karachi, Pakistan. Pak J Med Sci. 2022;38(5):---------. doi: https://doi.org/10.12669/pjms.38.5.4999
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Knowledge, attitudes and practices relating to antibiotic use and resistance among prescribers from public primary healthcare facilities in Harare, Zimbabwe
Authors: Olaru Ioana D. , Ferrand Rashida A. , Yeung Shunmay , Chingono Rudo , Chonzi Prosper , Masunda Kudzai P.E. , Dixon Justin , Kranzer Katharina 
Published: April 2022

Background Overuse of antibiotics is one of the main drivers for antimicrobial resistance (AMR). Globally, most antibiotics are prescribed in the outpatient setting. This survey aimed to explore attitudes and practices with regards to microbiology tests, AMR and antibiotic prescribing among healthcare providers at public primary health clinics in Harare, Zimbabwe. Methods This cross-sectional survey was conducted in nine primary health clinics located in low-income suburbs of Harare between October and December 2020. In Zimbabwe, primary health clinics provide nurse-led outpatient care for acute and chronic illnesses. Healthcare providers who independently prescribe antibiotics and order diagnostic tests were invited to participate. The survey used self-administered questionnaires. A five-point Likert scale was used to determine attitudes and beliefs. Results A total of 91 healthcare providers agreed to participate in the survey. The majority of participants (62/91, 68%) had more than 10 years of work experience. Most participants reported that they consider AMR as a global (75/91, 82%) and/or national (81/91, 89%) problem, while 52/91 (57%) considered AMR to be a problem in their healthcare facilities. A fifth of participants (20/91, 22%) were unsure if AMR was a problem in their clinics. Participants felt that availability of national guidelines (89/89, 100%), training sessions on antibiotic prescribing (89/89, 100%) and regular audit and feedback on prescribing (82/88, 93%) were helpful interventions to improve prescribing. Conclusions These findings support the need for increased availability of data on AMR and antibiotic use in primary care. Educational interventions, regular audit and feedback, and access to practice guidelines may be useful to limit overuse of antibiotics.
Incidence of invasive non-typhoidal Salmonella in Blantyre, Malawi between January 2011-December 2019
Authors: Wilson Catherine N. , Chunga Angeziwa , Masesa Clemens , Denis Brigitte , Silungwe Niza , Bilima Sithembile , Galloway Heather , Gordon Melita , Feasey Nicholas A. 
Published: April 2022

Background: The Malawi-Liverpool Wellcome Trust Clinical Research Programme (MLW) has undertaken sentinel surveillance of bloodstream infection and meningitis at Queen Elizabeth Central Hospital (QECH), Blantyre, Malawi for 20 years. Previously, three epidemics of Salmonella bloodstream infection have been identified. Here we provide updated surveillance data on invasive non-typhoidal Salmonella disease from 2011 – 2019. Methods: Surveillance data describing trends in invasive non-typhoidal Salmonella disease and associated antimicrobial susceptibility profiles are presented for the period January 2011 – December 2019. Results: Between January 2011-December 2019, 128,588 blood cultures and 40,769 cerebrospinal fluid cultures were processed at MLW. Overall, 1.00% of these were positive for S. Typhimurium, 0.10% for S. Enteritidis, and 0.05% positive for other Salmonella species. Estimated minimum incidence of invasive non-typhoidal Salmonella (iNTS) disease decreased from 21/100,000 per year in 2011 to 7/100,000 per year in 2019. Over this period, 26 confirmed cases of Salmonella meningitis were recorded (88.5% S. Typhimurium). Between 2011-2019 there was a substantial decrease in proportion of S. Typhimurium (78.5% to 27.7%) and S. Enteritidis (31.8% in 2011 to 0%) that were multidrug-resistant. Resistance to fluoroquinolones and third-generation generation cephalosporins (3GC) remained uncommon, however 3GC increased amongst Salmonella spp. and S. Typhimurium in the latter part of the period. Conclusions: The total number of iNTS bloodstream infections decreased between 2011-2019. Although the number multidrug resistance (MDR) S. Typhimurium and S. Enteritidis isolates has fallen, the number of MDR isolates of other Salmonella spp. has increased, including 3GC isolates.
Just Diverse Among Themselves: How Does Negative Performance Feedback Affect Boards’ Expertise vs. Ascriptive Diversity?
Authors: Jung HeeJung , Lee Yonghoon G. , Park Sun Hyun 
Published: April 2022

We investigate how negative performance feedback affects board diversity, which is instrumental in shaping a firm’s strategic change. When a firm underperforms compared with its aspiration, its board is motivated to promptly address the underperformance. The board needs to not only help search for strategic alternatives but also quickly build consensus around its strategic reorientation. These two motivations lead the board to value two dimensions of diversity among its members differently. On the one hand, to understand the problem of underperformance and find a solution, the board is motivated to seek new expertise, avoiding redundancy in the pool of expertise already represented in the boardroom. This results in a higher level of diversity in director expertise. On the other hand, the urgent need to build consensus prompts the board to value trust and solidarity and to avoid potential conflict among directors. Because people perceive others with similar ascriptive backgrounds as trustworthy, changes in the board of an underperforming firm are likely to yield a lower level of diversity in its members’ ascriptive backgrounds. These changes in board are affected by the committee chairs of the board whose power and influence are significant in the boardroom. Analyses of the boards of 733 U.S. listed manufacturing firms show that when a firm underperforms compared with its aspirations, it increases the board expertise diversity, but decreases the board ascriptive diversity. When chairs on the board are gender or racial minorities, the negative association between underperformance and the board ascriptive diversity is weakened. Supplemental Material: The e-companion is available at https://doi.org/10.1287/orsc.2022.1595 .
Shift Share Location Quotient, and ARIMA Forecasting Methods in the Analysis of the Competitiveness of Tual City and the Economic Growth of the Maluku Province.
Authors: La Adisamu Nova Prista , Endroyono Endroyono , Nugroho Sumpeno Mardi Susiki 
Published: April 2022

Abstract— Economic development and high competitiveness are significant factors in a region’s success, especially since the enactment of Law Number 32 of 2004 on Regional Government, which converted the centralized to a decentralized system. This study analyzes the GRDP data of Tual City and Maluku Province using the shift share method and the Location Quotient method, resulting in a shift share assessment of Tual City’s regional competitiveness. It can be seen that the economic state of Tual City is still influenced by the Maluku Province’s economic growth of 593,688 with an overall slowdown in Proportional Shift of (-633.686) and an differential shift of (-5,756.040) during 9 years. The ARIMA forecasting method was then used to project the province’s 5th-year economic growth of 8,486,707 (billions) in the 5th period.
Fiber optic sensor for nondestructive detection of microbial growth on a silk surface
Authors: Xue Zhengda , Yu Qiuhui , Zhong Nianbing , Zeng Tan , Tang Huan , Zhao Mingfu , Zhao Ya , Tang Bing 
Published: April 2022

To nondestructively detect the mold growth process on silk, a coaxial concave reflection conical fiber optic sensor was developed using conical quartz fibers, fiber connectors, fiber couplers, and a plastic fixator. We established a theoretical model of this sensor and studied the influence of its structural parameters on its sensitivity, characterized the morphology of Aspergillus niger, and detected its growth process on a silk surface. A linear relationship between the sensor’s output signal and the mold height was found. The sensor sensitivity, maximum detection error, and low limit of detection were 2.4 E-5 AU/µm, 7.83%, and 10 µm, respectively.
Deep reinforcement with spectrum series learning control for a mode-locked fiber laser
Authors: Li Zhan , Yang Shuaishuai , Xiao Qi , Zhang Tianyu , Li Yong , Han Lu , Liu Dean , Ouyang Xiaoping , Zhu Jianqiang 
Published: April 2022

A spectrum series learning-based model is presented for mode-locked fiber laser state searching and switching. The mode-locked operation search policy is obtained by our proposed algorithm that combines deep reinforcement learning and long short-term memory networks. Numerical simulations show that the dynamic features of the laser cavity can be obtained from spectrum series. Compared with the traditional evolutionary search algorithm that only uses the current state, this model greatly improves the efficiency of the mode-locked search. The switch of the mode-locked state is realized by a predictive neural network that controls the pump power. In the experiments, the proposed algorithm uses an average of only 690 ms to obtain a stable mode-locked state, which is one order of magnitude less than that of the traditional method. The maximum number of search steps in the algorithm is 47 in the 16°C–30°C temperature environment. The pump power prediction error is less than 2 mW, which ensures precise laser locking on multiple operating states. This proposed technique paves the way for a variety of optical systems that require fast and robust control.