bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graft Patency Assessment with CCTA Using a Comprehensive Singlebranch Bridging Score
Authors: Xiao Jianwei , Wang Xiang , Huang Zengfa , Yang Yang , Du Xinyu , Wang Xi , Li Zuoqin , Hu Yun , Li Xiang 
Published: October 2022

Aims:This study aims to assess the prognostic value of graft patency with coronary computed tomography angiography (CCTA) using a comprehensive single-branch targeted atherosclerotic risk score (CSBS) in patients before coronary artery bypass grafting (CABG).Methods:This retrospective study contains a total of 88 patients who underwent clinical CCTA before off-pump CABG surgery between 2015 and 2018. Graft failure was defined as patients with missing multi-slice CCTA or coronary angiography. The predictive value of CSBS (ranging from 0-70 and divided into 2 groups: < 20 and ≥20) was analyzed using Kaplan–Meier analysis and Cox regression models.Results:Patients' mean age was 61.2 ± 10.5 years, with a mean follow-up of 20.4 ± 15.2 months. A total of 203 grafts (21.5% arterial grafts) were analyzed and 30 of the vessels were occluded (14.8%). There was no significant difference in graft occlusion among the three targeted vessel groups. The Cox proportional hazard analysis showed that CSBS < 20 was a significant predictor of graft failure.Conclusion:Lower comprehensive single-branch targeted atherosclerotic risk score evaluated by CCTA is an independent prognostic factor for graft failure in patients before CABG surgery.
LGR5 As a Potential Therapeutic Target for Breast Cancer: A Systematic
Review and Meta-analysis
Authors: Razavi-Amoli Seyedeh-Kiana , Omrani-Nava Versa , Heydari Keyvan , Kaidarova Dilyara , Alizadeh-Navaei Reza 
Published: October 2022

Background and Objective:
Breast cancer is the world's most common malignancy. Despite
significant advances in the diagnosis and treatment of the disease, the associated mortality rate is still
high. Tumor initiating cells known as cancer stem cells with unique abilities are suspected responsible for
therapy failure and poor prognosis. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5)
is a cancer stem cell marker that promotes aggressive features in breast cancer cells. So, the aim of this
study was to perform a systematic review and meta-analysis to evaluate LGR5 as a therapeutic target for
breast cancer.

Methods:
This systematic review and meta-analysis were performed using databases of Web of Science,
Scopus, and PubMed. We searched these databases with LGR5 and Breast Cancer and related keywords
based on the mesh database until Oct12, 2021. All studies that reported the rate of LGR5 high expression
with Immunohistochemistry in breast cancer patients were included in this review. We used the STATA
and random effect models for data analysis.

Results:
Finally, 7 studies including 2632 breast cancer samples were studied. The pooled prevalence of LGR5 high expression in breast cancer was 36 % (CI95%: 26-47.5%, I2= 95.5) and in triple negative was 48.6% (CI95%: 38.4-58.7%, I2= 0.0).

Conclusion:
Finally, 7 studies including 2632 breast cancer samples were studied. The pooled prevalence of
LGR5 high expression in breast cancer was 48.6 % (CI95%: 40.5-56.7%, I2=0.0) and in triple negative
was 48.6% (CI95%: 38.4-58.7%, I2= 0.0).
Transport Poverty: A Comparative Study between South Africa and Nigeria
Authors: Popoola Ayobami , Akogun Olawale , Magidimisha-Chipungu Hangwelani , Chipungu Lovemore 
Published: October 2022

Background:
Achieving the Sustainable Development Goals (SDGs) and neighbourhood liveability is dependent on an improved transportation sector. Urban transport is conceptualized as either mobility or accessibility; thus, it remains an integral part in enhancing urban livelihood and serves as a hub connecting all sectors of a city's economy. Lack of access to opportunities and/or services, inadequate transport services, and physical or financial inaccessibility to transport options are prevailing in African cities and have been used to conceptualize transport poverty.

Objectives:
This study seeks the relationship between some dimensions of transport poverty and life satisfaction. The argument put forward in this study is that transport poverty predicts life satisfaction that is a vital aspect of subjective wellbeing.

Methods:
The study utilise an exploratory, comparative design that will enable the comparison of dimensions of Transport Poverty in Ibadan, Nigeria, and Durban, South Africa. For this study, communities in both Ibadan and Durban were randomly selected; while data were collected through an online survey method. The hypothesis that spatial exclusion mediates the relationship between service availability and satisfaction with life, transport disadvantaged and satisfaction with life, and transport reliability and satisfaction with life were tested through mediation analysis.

Results:
For the first hypothesis, partial mediation existed; for the second hypothesis, no mediation existed; for the third hypothesis, total mediation existed. Lastly, spatial exclusion varied between the two countries.

Conclusion:
The study concludes that a transport network that is not reliable leads to spatial exclusion, which in turns affects satisfaction with life. Likewise, all dimensions of transport poverty are similar except for spatial exclusion which differs between the countries, with South Africans experiencing more cases of spatial exclusion as compared to Nigerians.
An Autonomous Adaptive Enhancement Method Based on Learning to
Optimize Heterogeneous Network Selection
Authors: Sucharitha Yadala , Shaker Reddy Pundru Chandra 
Published: October 2022

Aims and Background:
Mobile workstations are frequently used in challenging environments
of heterogeneous networks. Users must move between various networks for a myriad of purposes,
including vertical handover. At this time, it is critical for the mobile station to quickly pick the
most appropriate networks from all identified alternative connections with the decision outcome,
avoiding the ping-pong effect to the greatest extent feasible.

Objectives and Methodology:
Based on a combination of network characteristics as well as user
choice, this study offers a heterogeneous network selection method. This technique integrates three
common Multi-Attribute Decision-Making (MADM) techniques, notably the Fuzzy Analytic Hierarchy
Process (FAHP), Entropy, and Technique for Order Preference by Similarity to Ideal Solution
(TOPSIS), to take into consideration user preferences for every prospective network as well as the real
scenario of heterogeneous networks. For different traffic classes, FAHP is first utilized to determine
the weights of network parameters and the utility numbers of total options available. Next, entropies
and TOPSIS are utilized to obtain only the unbiased weights of network factors and utility principles
of totally different options.

Results:
The most suitable networks, whose utility number is the greatest and larger than that of the
equivalent number of present networks of the phone station, are chosen to provide accessibility based
on the utility numbers of each prospective system as a limit. The suggested method not only eliminates
a particular algorithm's one-sided character but also dynamically changes the percentage of each
method in the desired outcome based on real needs.

Conclusion:
The proposed model was compared to the three existing hybrid methods. The results
showed that it could precisely choose the optimized network connectivity and significantly reduce the
value of vertical handoffs. It also provides the requisite Quality of Service (QoS) and Quality of Everything
(QoE) in terms of the quantitative benefits of vertical handovers.
Frequency Coordinated Control of Wind Power Flexible Direct System
Based on Voltage Sourced Converter Based Multi-Terminal High Voltage
Direct Current
Authors: Li Congshan , Zhen Zikai , He Ping , Liu Yan , Zhong Pu 
Published: October 2022

Background:
With the continuous penetration of renewable energy in modern power
systems, the problem of excessive frequency deviation of power systems, which is caused
by the integration of wind power into electricity grids, needs to be solved urgently.

Objective:
Make up for frequency fluctuations when AC systems fail, improve the frequency
characteristics of main system networks, and reasonably distribute unbalanced power.

Methods:
According to the principle of active power distribution, a frequency division coordinated
control strategy that uses low-pass filter control to divide power fluctuations into highfrequency
fluctuations and low-frequency fluctuations is proposed. High-frequency fluctuations
are attached to the wind farm side, and low-frequency fluctuations are attached to the DC
system to realize frequency division control.

Result:
The simulation results showed that the coordination of the frequency division control
of the wind farm and flexible DC system could effectively reduce the main grid’s frequency
fluctuations, which are caused by the AC system failure, and improve the stable operation
ability of the AC and DC systems.

Conclusion:
The frequency division control can overcome the unbalanced power distribution
caused by traditional droop control, reduce the frequency deviation of the AC system, realize
frequency autonomy, and enhance system robustness.
INFORMATION AND PSYCHOLOGICAL SECURITY AS A SCIENTIFIC RESEARCH DEFINITION
Authors: Рерке Виктория Игоревна , Бубнова Ирина Сергеевна , Демаков Владимир Иванович 
Published: October 2022

Изучается научная дефиниция «информационно-психологическая безопасность» как проблемное поле пересечения информационной и психологической безопасности. Научно обосновано, что информационно-психологическая безопасность личности – это сегмент вопроса общей безопасности. Актуализированы научные представления о проблемах информационной безопасности и психологической опасности. Анализируются разные подходы к проблеме информационно-психологической безопасности личности: безопасность как чувство защищенности личности; отсутствие угроз; умение управлять собой; наличие социального опыта. Определены и сопоставлены объекты психологической и информационной безопасности. Доказано, что информационно-психологическая безопасность входит в категорию «Психологическая безопасность личности». Обосновано положение, что информационно-психологическая безопасность состоит из возможности личности противостоять негативному влиянию социума. В заключение выделены направления развития информационно-психологической безопасности: способности определять и противодействовать негативному информационно-психологическому воздействию и психологическая безопасность личности.
The scientific definition of “information and psychological security” as a problematic field of intersection of information and psychological security is studied. Scientific ideas about the problems of information security and psychological danger are updated. It is scientifically substantiated that the information and psychological security of a person is a segment of the issue of general security. Different approaches to the problem of information and psychological security of individual are analyzed: a security as a sense of protection among the individual; an absence of threats; an ability to control yourself; a presence of social experience. It is proved that information-psychological security is included in the category of psychological security of the individual. The objects of psychological and information security are defined and compared. The objects and their content for the study of psychological safety are determined. The position is substantiated that information-psychological security consists of the ability of the individual to resist the negative influence of society. It has been proved that informational and psychological security falls into the category of psychological security of the person. Thus, the directions of information’s development and psychological security are highlighted. Such as the ability to identify and counteract negative informational and psychological impact and psychological security of the person.
Aplikasi Pengukuran Luas Daun Tanaman Menggunakan Pengolahan Citra Digital Berbasis Android
Authors: Andrian Rico , Agustiansyah Agustiansyah , Junaidi Akmal , Lestari Dian Indah 
Published: October 2022

Leaves are the most important organ in plants in the process of photosynthesis and will affect plant growth and productivity. Leaves also have a function as the main food maker. Leaf area is a very important parameter in the science of plant nutrition, measurement of plant protection, the relationship between water and soil in plants, plant ecosystems, plant fertility, etc. The use of leaf area measuring instruments that exist today has its drawbacks in terms of portability and practicality. The development of smartphone technology, one solution that can be used to overcome this is to design an application to measure the area of leaves by utilizing an android based smartphone camera. This research has been successfully made a leaf area calculation application that utilizes smartphone cameras using the OpenCV library. The application provided in this study is able to provide convenience and speed up the calculation of the leaf image area with an error rate of 4.9% and an accuracy of 95.1% from the average results of 10 leaf samples tested. Keywords : Image Processing, Leaf Area, Opencv, Android.
The Impact of Internal Control Practices on Fraud Prevention: The Case of Lebanese Small-Medium Enterprises
Authors: Alayli Sahar 
Published: October 2022

When compared to large corporations, Small and Medium Enterprises (SMEs) are far more likely to suffer from employee losses and much less likely to be able to absorb these losses. Small and Medium Enterprises (SMEs) are better able to handle internal control than large corporations. It appears that the people of Lebanon view this issue with sensitivity, it is rarely brought up in casual conversation. Since internal control is the main issue facing Lebanese businesses, they would rather not address it. Only 308 of 400 responders filled out the survey, and the results were evaluated with the use of the SPSS statistical package. Findings showed that businesses in the modern era urgently require monitoring systems, as new evidence shows that monitoring frameworks affect performance evaluations. The environment in which it operates shapes a company's management mindset. The monitoring setup provides the backbone upon which further layers of internal control may be built. Consequently, the study's subjects include the organizations' cultures and working styles and the ethics and ethical beliefs of the employees who create and execute controls. Many factors interact to maintain a stable ecosystem. A subset of the executive board and representatives from each board committee have been tasked with gathering the information necessary to complete this report at the request of the board of directors.
Effect of Biofertilizers and Farmyard Manure on Growth and Tuber Yield of Potatoes (Solanum tuberosum L.) in Highlands of Kenya
Authors: Abdirahman Said Hassan , Mafurah Joseph J. , Kimurto Paul K. , Nyongesa Moses W. 
Published: October 2022

Poor soil fertility is among the significant constraints to potato production in Kenya. Increased potato production currently depends on the use of chemical fertilizers for nutrients. The prices of chemical fertilizers continuously increase, becoming unaffordable for small-scale farmers who mostly grow potatoes. Therefore, the continuous use of chemical fertilizers such as NPK may cause complete depletion of other macro and micronutrients in potato production areas of Kenya. In addition, it increases the cost of inputs and triggers environmental pollution. The objective of this study was to evaluate alternative soil amendments using different biofertilizers in potato production. Two field experiments were conducted during the 2019 and 2020 seasons using two potato varieties (Shangi and Kenya mpya). The treatments were 30 t ha-1 of farmyard manure (FYM), two different biofertilizers (Trichoderma asperellum, T.R., and Bacillus subtilis, B.A.) applied at a rate of (150 mL/10 kg) and NPK (0 and 100 kg ha-1) as negative and positive controls respectively. Field experiments were carried out in randomized complete block design in a split-plot arrangement. The results indicated that FYM+TR increased potato yield and plant height by 19.81% and 18.99%, respectively, compared to the control. FYM+TR also increased tuber dry matter, marketable tuber weight, and potato grade by 25.15% 18.99%, respectively, compared to the positive control. The study recommends using FYM+TR and FYM+ BA for potato production in Kenya as they were found to increase crop performance and subsequent yield, which is beneficial to the environment and safe for farmers.
On the position of onomatopoeia in adult language. Evidence from Slovak
Authors: Gregová Renáta 
Published: October 2022

AbstractOnomatopoeic expressions are usually defined as verbal imitations of the sounds from the extra-linguistic reality. The position of onomatopoeia in languages varies cross-linguistically. In standard Slovak, onomatopoeia represents a sub-category of interjections. Onomatopoeic words are considered an important part of child’s vocabulary due to their sound-imitative nature and simple structure, but their role in language of the adults is not clear. The study presents the results of the research aimed at the analysis of the place of onomatopoeia in language of adult native Slovak language speakers. The research was carried out on the basis of two questionnaires in which the respondents were asked to (1) identify the sound imitated by the given onomatopoeia, that is, to identify the meaning of the onomatopoeia and (2) to capture the sound they heard by an existing lexicalized onomatopoeia. The research results indicate that although standard Slovak is a language relatively rich in lexicalized onomatopoeic expressions, adult natives are not very familiar with their meaning. Most of the respondents could not identify the sound mimicked by the given onomatopoeia and were not able to capture the sound by the existing lexicalized sound-imitating word. This finding supports the views about the marginal position of onomatopoeia in adult language.
Omotic lexicon in its Afro-Asiatic setting VI: Addenda to Omotic roots with *ḅ-, *ṗ-, *p- (or *f-)a
Authors: Takács Gábor 
Published: October 2022

Abstract
The paper is a new contribution to revealing the Afro-Asiatic heritage in the lexicon of the Omotic languages by means of interbranch comparison using a.o. the ancient Egypto-Semitic evidence.
Changes in the Lactoferrin Concentration in the Bovine Colostrum During Postpartum Period
Authors: Trajkovska Biljana , Kochoski Ljupche , Dimitrovska Gordana , Hajrulai-Musliu Zehra , Uzunov Risto , Petkov Vladimir , Badgujar Prarabdh C. 
Published: October 2022

Abstract
The health condition of the mammary gland is highly crucial for obtaining good quality colostrum. The lactoferrin (LF), as an iron-binding protein, plays a key role in the defense mechanisms of the mammary gland due to its’ bacteriostatic properties. The study aimed to investigate the factors affecting the LF concentration in the bovine colostrum milk during the postpartum period, and the effect of somatic cell count (SCC) on the LF concentration and milk composition. The cows were randomly selected at a dairy farm in Pelagonia region. Colostrum samples from 12 cows were collected. Samples were taken at different time intervals after parturition, 1, 6, 12, 24, 48, 72, 96, and 120 h after parturition. Cows in their second parity were found to have higher levels of LF compared to cows in the third and higher parity (p>0.05). Time had a significant effect on the LF concentration (p<0.01), with the highest value recorded 1 h after parturition remaining stable for one hour. LF concentration and SCC in the colostrum showed a weak positive correlation (r=0.40; p<0.01). The highest LF concentration was noticed when SCC was above 800,000 cells/mL. In conclusion, the colostrum LF concentration was significantly affected by the interactions of the two factors, i.e., time after parturition and SCC (p<0.05). Milk composition was affected by elevated SCC. Parity showed no association with LF. The SCC can be used as a reliable means of assessing colostrum quality.
Suppression Effects of Excessively Expressed Gene BCL-2 in Cell Lines of Prostate Cancer
Authors: Esmerov Igor , Atanasov Branko , Angelevska Aleksandra , Chrcheva Radmila , Mickov Ljupco , Angelovski Ljupco , Josifovska Slavica , Markov Nikolaj , Adamov Nikola 
Published: October 2022

Abstract
The aim of this study was to construct two plasmid-specific shRNA transcripts of the bcl-2 gene in order to prepare for reverse of cell apoptosis. The plasmid was designed according to a previously published sequence of interfering RNA following an appropriate reference, using appropriate software. By annulling complementary oligonucleotides, double-stranded inserts were formed. Recombinant shRNA-encoding plasmids were constructed by digestion of psiRNA-x7SKGFPzeo plasmid (psiRNA-x7SKGFPzeo, with restrictive endonuclease BbsI electrophoresis in ultra-pure agarose with low melting point (LMP-Agarose). For each of the constructs, a suitable double-stranded insert downstream of x7SK (strong RNA III promoter) with T4 DNA ligase was cloned. The control plasmid psiRNAScr was used directly for transformation. The PC-3 cell lines were transfected with 2 plasmids, psiRNA-Bcl-2 and psiRNAScr to suppress the bcl-2 gene construct. The results have shown that the lowest level of bcl-2 genes was 48 h, and even lower 72 h after the transfer, and the mRNA levels returned to normal in 120 h. An increase in the percentage of cells with spontaneous apoptosis has been observed with successful inhibition of the bcl-2 gene. The induction of apoptosis in transfected cells increased the percentage of necrotic cells proportionally. The percentage of apoptotic cells transfected with psiRNA-bcl-2 plasmid increased proportionally to the increase of hydrogen peroxide concentration. The transfection of the PC-3 cell line from prostate cancer with constructed shRNA plasmid has induced suppression of bcl-2 gene expression versus control Scr plasmid. Suppression of bcl-2 gene expression significantly increased cell sensitivity to apoptosis induction.
Sea Buckthorn Diseases Caused by Pathogenic Fungi
Authors: Drevinska Kristīne , Moročko-Bičevska Inga 
Published: October 2022

Abstract
Sea buckthorn (Hippophae rhamnoides L.) is a native species in various regions of Asia and Europe. It is cultivated as a multipurpose horticultural species in northern temperate regions of Europe, Asia, and North America with large economic potential used for food, pharmacology, cosmetics, and environmental conservation. Diseases in natural populations and managed landscapes have increased, endangering sea buckthorn growth and cultivation worldwide. This review article focuses on sea buckthorn canker, wilt and decline diseases caused by pathogenic fungi, their distribution, hosts of involved pathogenic fungi and symptoms. Published information on sea buckthorn fungal diseases is available only about a few diseases, such as wilt (Verticillium dahliae), the dried-shrink disease caused by various fungi and abiotic factors, and stem canker (Hymenopleella hippophaeicola, Cytospora spp., Stigmina sp.). Some fungi reported on sea buckthorn are poorly studied, or the sea buckthorn is a newly discovered host, as in the case of Eutypa spp. The most often reported symptoms of these diseases are cankers and cracks on trunks and main branches, dead buds and leaves, necrosis of various tissues on branches, and root necrosis, resulting in the death of the shrubs. In general, the fungal diseases on sea buckthorn are not sufficiently addressed, and more research is needed.