bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesizing Structured Optical Vortices
Authors: Ikonnikov Denis A. , Fokin Viacheslav A. , Vyunishev Andrey M. 
Published: May 2022

AbstractA noniterative approach to generation of binary phase holograms is applied for synthesizing complex optical vortex arrays. This approach does not use inverse Fourier analysis and allows one to obtain arbitrary optical vortex arrays with specified topological charges, which cannot be obtained using conventional fork‐shaped gratings. A topological charge of individual optical vortices generated using binary phase holograms can be specified at a given spatial frequency, so that the equidistant array of optical vortices can be generated via illuminating a hologram by a beam with the zero topological charge. The results of the calculation are consistent with the experimental data, including those of the interferometric measurements. The approach also makes it possible to synthesize superimposed optical vortices, where an optical field represents well‐ordered circular arrays of optical singularities. An unusual behavior of phase dislocations in superimposed structures is found. For two optical vortices of same reciprocal lattice vectors, but different topological charges, spatial distribution of singularities are reconfigured in a such manner that a couple of concentric circular arrays of singularities appear. The proposed binary phase holograms offer new opportunities for synthesizing the complex optical vortex light fields, which can find light–matter interaction‐based applications.
A two‐loop group formation tracking control scheme for networked tri‐rotor UAVs using an ARE‐based approach
Authors: Bhowmick Parijat , Bhadra Shantanu , Panda Atanu 
Published: May 2022

AbstractCooperative control of networked unmanned aerial vehicles (UAVs) has received significant research interest over the last decade due to its potential applications in military security and surveillance, search and rescue, planetary exploration, precision agriculture, and so on. Many of these practical activities can be formulated as a group formation tracking problem with multiple targets to track. This paper aims to address such problems via designing a cooperative control scheme for networked tri‐rotor UAVs connected with directed graph topology. The proposed methodology consists of a two‐loop control scheme—the inner loop applies a robust feedback linearization technique to linearize the coupled, nonlinear dynamics of the tri‐rotor UAVs; while the outer loop facilitates an ARE‐based cooperative group formation tracking scheme. Tri‐rotor UAVs are considered in this paper instead of quad‐rotor UAVs, which are more common in drone applications, to conquer a major limitation of the quad‐rotor UAVs that it cannot alter its attitude independently while hovering at a particular height. A rigorous theoretical proof is given to establish the two‐loop control scheme exploiting the Lyapunov stability approach and algebraic Riccati equation (ARE)‐based optimal control policy. An in‐depth case study on a multitarget surveillance mission has been performed in this paper using a virtual reality software simulation platform to demonstrate the usefulness and efficacy of the proposed scheme.
Life cycle assessment of the wood pallet repair and remanufacturing sector in the United States
Authors: Alanya‐Rosenbaum Sevda , Bergman Richard , Gething Brad , Mousavi‐Avval Seyed Hashem 
Published: May 2022

AbstractWood pallets are ubiquitous products that can be recovered and reused to enhance their service life and environmental performance. Repair/remanufacturing has an important role in extending the service life of the wood pallet. To quantify environmental performances of wood pallet reuse, this study developed representative life cycle inventory data for pallet repair/remanufacturing in the United States based on comprehensive industry‐wide production data for 2018. A gate‐to‐gate life cycle assessment covering raw material supply, raw material transportation and pallet repair/remanufacturing showed that repair/remanufacturing often had the highest impacts, including primary energy consumption at 5.09 MJ and global warming impact at 0.355 kg CO2 eq per repaired/remanufactured pallet. Electricity consumed onsite followed by nail input and the fuel used by forklifts during the manufacturing drove much of the impacts on the environment. The results of this study provide valuable information on the repair/remanufacturing impacts, allowing quantification and evaluation of the recovery stage on the overall environmental performance of wood pallets. © 2022 Society of Chemical Industry and John Wiley & Sons, Ltd.
Spectrofluorimetric determination of the anti‐Covid 19 agent, remdesivir, in vials and spiked human plasma
Authors: Attia Tamer Z. , Boushra John M. , Abdel Hakiem Ahmed F. , Lashien Adel S. , Noureldeen Deena A. M. 
Published: May 2022

AbstractFollowing the sudden widespread of the novel coronavirus (COVID‐19) which first appeared in Wuhan city. Remdesivir (REM) was the first medicine licensed by the US Food and Drug Administration (FDA) for COVID‐19 infected hospitalized patients. Hence, there was an urgent demand for the optimization of efficient selective and sensitive methods to be developed for the determination of REM in pharmaceuticals as well as biological samples. A sensitive and simple green spectrofluorimetric method has been developed to determine REM in pharmaceutical formulation, in addition to, spiked human plasma. The technique involves measuring the native fluorescence of REM in distilled water at 410 nm followed by excitation at 241 nm, giving a linear relationship over the range 50.00–500.00 ng/mL, and then improving the sensitivity of REM through micellar formation using 2.00% w/v sodium dodecyl sulfate (SDS). A linear relationship has been obtained over the range 10.00–350.00 ng/mL having detection and quantitation limits of 2.34 and 7.10 ng/mL, respectively. Different analytical parameters have been carefully studied. A validation study has been conducted successfully in accordance with the FDA and the International Council for Harmonization of Technical Requirements for Pharmaceuticals for Human Use (ICH) guidelines. The developed methods' greenness was assessed utilizing a greenness profile and analytical eco‐scale standards. Both methods were discovered to be environmentally friendly and could be successfully used for the determination of the studied drugs in pharmaceutical formulation and human plasma with good accuracy and high precision. As a result, the developed spectrofluorimetric methods could be ideally suited for determination of REM in quality control and medicinal laboratories.
Comparisons make faces more attractive: An ERP study
Authors: Han Shangfeng , Hu Jie , Gao Jie , Fan Jiayu , Xu Xinyun , Xu Pengfei , Luo Yuejia 
Published: May 2022

AbstractFacial attractiveness judgment largely depends on the characteristics of the facial structure and the personality of the observer. However, little is known about the influence of contextual variations on facial attractiveness. In this electroencephalogram study, participants judged the attractiveness of faces presented individually or in pairs with either a higher‐attractive face (HAF) or lower‐attractive face (LAF). The attractiveness judgment rating of the target face was significantly higher when presented in pairs with HAFs or LAFs than when presented individually and was accompanied by a larger late positive complex. These results suggest that contextual faces enhance the attractiveness judgment of target faces. Microstate analyses revealed that the global field power (GFP) of state 3 was significantly correlated with the attractiveness judgment in the HAF condition whereas the GFP of state 2 was significantly correlated with the attractiveness judgment in the LAF condition. Interestingly, the GFP of state 2 mediated the relationship between narcissism and facial attractiveness judgment in the context of LAFs. Source location analyses showed that states 3 and 2 activated the superior and middle frontal gyrus, which are involved in emotion processing. Our findings suggest that facial attractiveness can be enhanced by contextual comparison with other faces, subject to personality of the observer.
Overexpression of BDNF in the ventrolateral periaqueductal gray regulates the behavior of epilepsy–migraine comorbid rats
Authors: Wang Long , Fu Lu‐Lan , Deng Zi‐Ru , Zhang Juan , Zu Mei‐Dan , Wu Jun‐Cang , Wang Yu 
Published: May 2022

AbstractObjectiveTo investigate the effects of brain‐derived neurotrophic factor (BDNF) overexpression in the ventrolateral periaqueductal gray (vlPAG) on behavioral changes in epilepsy–migraine comorbid rats.MethodWe used an adeno‐associated virus (AAV)‐mediated vector to supplement BDNF in the vlPAG area prior to the establishment of a pilocarpine‐nitroglycerin (Pilo‐NTG) combination‐induced comorbid model of epilepsy and migraine. Seizure‐ and migraine‐related behaviors were analyzed. Cell loss and apoptosis in vlPAG were detected through hematoxylin‐eosin (HE) and TUNEL staining. Immunofluorescence staining analyses were employed to detect expressions of BDNF and its receptor, tyrosine kinase B (TrkB), in vlPAG. Immunohistochemical staining was conducted to detect expressions of c‐Fos and calcitonin gene‐related peptide (CGRP) in the trigeminal nucleus caudalis (TNC) and trigeminal ganglion (TG).ResultsComparing to control group, AAV–BDNF injected comorbid group showed lower pain sensitivity, scratching head, and spontaneous seizures accompanied by the downregulation of c‐Fos labeling neurons and CGRP immunoreactivity in the TNC and TG. However, these changes were still significantly higher in the comorbid group than those in both epilepsy and migraine groups under the same intervention.ConclusionThese data demonstrated that supplying BDNF to vlPAG may protect structural and functional abnormalities in vlPAG and provide an antiepileptic and analgesic therapy.
Habitual tea consumption and postoperative delirium after total hip/knee arthroplasty in elderly patients: The PNDABLE study
Authors: Lin Xu , Li Xiao‐xuan , Dong Rui , Wang Bin , Bi Yan‐lin 
Published: May 2022

AbstractPurposeTo clarify the effects of habitual tea consumption on postoperative delirium (POD) in elderly patients undergoing total hip/knee arthroplasty.Patients and MethodsA prospective cohort study was carried out at Qingdao Municipal Hospital Affiliated to Qingdao University between June 2020 and June 2021. A total of 332 patients aged 65–85 years undergoing total hip/knee arthroplasty under combined spinal and epidural anesthesia were enrolled from the Perioperative Neurocognitive Disorder and Biomarker Lifestyle (PNDABLE) study in the final analysis, consisting of 168 patients with habitual tea consumption and 164 patients with infrequent tea consumption. The primary endpoint was the effects of habitual tea consumption on POD and the incidence of POD, which was assessed by the Confusion Assessment Method (CAM) twice daily during the first 7 postoperative days, and POD severity was measured by the Memorial Delirium Assessment Scale (MDAS). The secondary endpoints were the concentrations of caffeine and tea polyphenols in plasma and cerebrospinal fluid (CSF), which were detected by the enzyme‐linked immunosorbent assay.ResultsPOD occurred in 61 of 332 patients (18.37%), among whom 19 had habitual tea consumption (5.72%) and 42 had infrequent tea consumption (12.65%). Habitual tea consumption (odds ratio [OR] = 0.370, 95% confidence interval [CI]: 0.205–0.670, P = .001) was significantly associated with POD in the logistic analysis, and then after adjusting for age and American Society of Anesthesiologists (ASA) physical status (OR = 0.353, 95% CI: 0.190–0.655, P = .001). Furthermore, caffeine in T0 plasma (OR = 0.834, 95% CI: 0.752–0.924, P = .001), T1 plasma (OR = 0.818, 95% CI: 0.738–0.908, P < .001), and CSF (OR = 0.899, 95% CI: 0.820–0.984, P = .022) and tea polyphenols in T0 plasma (OR = 0.541, 95% CI: 0.416–0.704, P < .001), T1 plasma (OR = 0.477, 95% CI: 0.359–0.633, P < .001), and CSF (OR = 0.526, 95% CI: 0.397–0.696, P < .001) were associated with POD after adjusting for age and ASA physical status.ConclusionHabitual tea consumption may be associated with a lower incidence of POD in elderly patients.
Exploring moderators of the relationship between adolescents' social responsibility and civic actions
Authors: Le Trang U. , Johnson Sara K. , Lerner Jacqueline V. 
Published: May 2022

AbstractScholars have regarded social responsibility as a motivator of civic actions. Social responsibility, however, does not consistently lead to civic actions. Informed by sociopolitical development theory and social cognitive theory, the present study examined critical reflection about societal inequalities and intentional self‐regulation as potential moderators of the relationships between adolescents' social responsibility and political activities, social activism and community service. Survey data were collected from 737 adolescents in the Northeastern United States (Mage = 14.52, 58.2% girls, 57.5% White/European American). Path analysis indicated that social responsibility was associated with all three types of civic actions, and critical reflection moderated the relationship between social responsibility and political activities. We discussed limitations, implications and directions for future research. See Supplementary Material section to find this article's Community and Social Impact Statement.
Transcatheter aortic valve implantation with the novel‐generation Navitor device: Procedural and early outcomes
Authors: Corcione Nicola , Berni Andrea , Ferraro Paolo , Morello Alberto , Cimmino Michele , Albanese Michele , Nestola Luisa , Bardi Luca , Pepe Martino , Giordano Salvatore , Biondi‐Zoccai Giuseppe , Rigattieri Stefano , Giovannelli Francesca , Giordano Arturo 
Published: May 2022

AbstractTranscatheter aortic valve implantation (TAVI) has proved beneficial in patients with severe aortic stenosis, especially when second‐generation devices are used. We aimed at reporting our experience with Navitor, a third‐generation device characterized by intrannular, large cell, and cuffed design, as well as high deliverability and minimization of paravalvular leak. Between June and December 2021, a total of 39 patients underwent TAVI with Navitor, representing 20% of all TAVI cases. Mean age was 80.0 ± 6.7 years, and 14 (36.8%) women were included. Severe aortic stenosis was the most common indication to TAVI (37 [97.4%] cases), whereas 2 (5.3%) individuals were at low surgical risk. Device and procedural success was obtained in all patients, with a total hospital stay of 6.6 ± 4.5 days. One (2.9%) patient required permanent pacemaker implantation, but no other hospital events occurred. At 1‐month follow‐up, a cardiac death was adjudicated in an 87‐year‐old man who had been at high surgical risk. Echocardiographic follow‐up showed no case of moderate or severe aortic regurgitation, with mild regurgitation in 18 (47%), and none or trace regurgitation in 20 (53%). The Navitor device, thanks to its unique features, is a very promising technology suitable to further expand indications and risk‐benefit profile of TAVI.
Right ventricular hematoma: A rare but potentially fatal complication of percutaneous coronary artery intervention
Authors: van Hattem Veerle A. E. , Otterspoor Luuk C. , Lipsic Erik , Vlaar Pieter‐Jan J. J. 
Published: May 2022

AbstractRight ventricular hematoma secondary to coronary artery perforation during the percutaneous coronary intervention (PCI) is a rare complication. Nevertheless, with the growth of complex PCIs, including chronic total occlusion procedures, this complication may increase in frequency. We describe three cases of subepicardial right ventricular hematoma after complex right coronary artery PCI with different outcomes. Two cases were successfully managed with medication only. One case was managed with medication and pericardial drainage, unfortunately with a fatal outcome. All cases emphasize the need for awareness concerning this complication, which warrants prompt diagnosis and adequate therapy.
Harlequin syndrome: An asymmetric face
Authors: Korbi Mouna , Boumaiza Sirine , Achour Asma , Belhadjali Hichem , Zili Jameleddine 
Published: May 2022

AbstractHarlequin syndrome corresponds to unilateral dysfunction of the sympathetic system, characterized by flush and unilateral hyperhidrosis associated with hypo or anhidrosis and paleness of the opposite side. It is, usually, idiopathic. Rarely, it may be associated with compressive organic processes, iatrogenic causes, and general diseases. It is a real therapeutic challenge.
Individual Dye Removal Efficiencies in a Ternary Dye Mixture by Electrocoagulation
Authors: Yücel Arzu Nur , Keskin Can Serkan , Özdemir Abdil 
Published: May 2022

AbstractElectrocoagulation (EC) of a synthetic ternary dye mixture was investigated using sacrificial iron electrodes. Erionyl Red (ER), Isolan Bordeaux (IB), and Remazol Red (RR) textile dyes were used for preparing the ternary solution. Different operational parameters, including initial dye concentrations, salt amount, current density, EC time, and pH, were analyzed to optimize removal efficiency and energy consumption conditions. After EC treatment, the individual remaining dye concentrations were calculated by applying classical least squares (CLS). The fastest removed dye was RR and the obtained efficiency was the highest as compared to the other two dyes. The energy consumption was also investigated.
Renewable Diesel from Palm Oil Using Bio‐Syngas from Palm Empty Fruit Bunches as a Hydrogen Source
Authors: Orozco Laura M. , Cardeño Fernando , Echeverri David A. , Rios Luis A. 
Published: May 2022

AbstractBiofuels have emerged as alternatives to fossil fuels for reducing CO2 emissions. Bio‐syngas obtained from palm empty fruit bunches was used in the hydrotreating of palm oil, yielding an oil conversion and a renewable diesel purity very similar to the values obtained when using pure H2, under similar reaction conditions. The presence of CO in bio‐syngas decreases the stability of the catalyst by coke deposition. However, this drawback can be circumvented by regenerating the catalyst or by converting CO into CO2 and H2 through the water‐gas shift (WGS) reaction. The use of bio‐syngas and its WGS product eliminates the need of an expensive H2 purification process, and the lower H2 purity in syngas is compensated by a moderate increase in the reaction time.
Further Exploration of the Benzimidazole Scaffold as TRPC5 Inhibitors: Identification of 1‐Alkyl‐2‐(pyrrolidin‐1‐yl)‐1H‐benzo[d]imidazoles as Potent and Selective Inhibitors
Authors: Sharma Swagat , L. Pablo Juan , Tolentino Kirsten T. , Gallegos Wacey , Hinman Jennifer , Beninato Madison , Asche MacKenzie , Greka Anna , Hopkins Corey R. 
Published: May 2022

AbstractThe transient receptor potential cation channel 5 (TRPC5) plays an important role in numerous cellular processes. Due to this, it has gained considerable attention over the past few years as a potential therapeutic target. Recently, TRPC5 has been shown to be involved in the regulation of podocyte survival, indicating a potential treatment option for chronic kidney disease. In addition, a recent study has shown TRPC5 to be expressed in human sensory neurons and suggests that TRPC5 inhibition could be an effective treatment for spontaneous and tactile pain. To understand these processes more fully, potent and selective tool compounds are needed. Herein we report further exploration of the 2‐aminobenzimidazole scaffold as a potent TRPC5 inhibitor, culminating in the discovery of 16 f as a potent and selective TRPC5 inhibitor.
The early‐life stress induced by oxytocin inhibition in p53 knockout mouse dams increases adulthood tumorigenesis in first and second generations
Authors: Stendardo Massimo , Renzi Chiara , Pallavi Rani , Roda Niccolò , Gambino Valentina , Casciaro Francesca , Persico Giuseppe , Giorgio Marco 
Published: May 2022

AbstractBackgroundEarly‐life stress due to poor parental care has been suggested to increase cancer risk, though, so far, no experimental evidence established a link between defective parental behavior and spontaneous tumorigenesis in progeny. Essential maternal behavior is regulated, in particular, by the oxytocin (OT) hormonal circuit, which in turn responds to stimuli from the offspring and impinges on the central nervous systems.MethodsBy providing L‐368,899 OT receptor (OTR) inhibitor to lactating mothers, we set up a model of defective maternal care in p53 knockout mice.ResultsThe progeny of these dams showed, later in life, higher cortisol levels, shortened life span and increased tumorigenic potential of bone marrow cells (BMC). Notably, these phenotypes were transmitted to the following generation.ConclusionsTherefore, the inhibition of OT function in mothers is a novel paradigm of early‐life stress that is inherited across generations and increases cancer risk in tumor‐prone mice.
The impact of corporate social responsibility directed toward employees on contextual performance in the banking sector: A serial model of perceived organizational support and affective organizational commitment
Authors: Bhatti Sabeen Hussain , Iqbal Kamran , Santoro Gabriele , Rizzato Fabio 
Published: May 2022

AbstractUsing the lenses of stakeholder and social exchange theory, we propose that both perceived organizational support (POS) and affective organizational commitment (AOC) play sequential mediating roles in the relationship between corporate social responsibility (CSR) directed toward employees and organizational citizenship behaviors (OCBs) of employees. The theoretical model was tested using a time lagged data. Further, the information pertaining to the organizational citizenship behaviors of the employees was collected by their immediate supervisors. The mediation hypotheses were tested using process method. Results confirmed a positive and significant relationship between perceived CSR directed toward employees and OCBs, as well as the sequential mediation effect of both POS and AOC between CSR directed toward employees and OCBs. Although the majority of the literature has studied the impact of CSR at the macro level, recently researchers have shifted their focus on the behavioral impact of such activities at the individual level. We particularly focus on CSR directed toward employees and our findings confirm that such CSR activities prove be critical for improving the performance outcomes of the employees.
Investigation of injection‐locked ring oscillators for process, voltage, and temperature‐aware low phase‐noise reference clock generation
Authors: Larijani Mohammad M. , Jalali Mohsen 
Published: May 2022

AbstractIn this paper, injection‐locked coupled ring oscillators (ROs) are studied regarding their capabilities for process, voltage, and temperature (PVT) compensated reference clock generation. A PVT resilient RO is implemented by means of injection‐locked coupled ROs where the injection locking mechanism is realized by employing adjustable coupling factors. It is shown that the oscillation frequency can be highly compensated for temperature‐related variations through the coupling factors. In addition, it is possible to compensate the center oscillation frequency for process‐induced variations and supply voltage fluctuations. The proposed technique is fully open loop without any frequency tracking loop and can be easily adopted by other architectures of oscillators such as RC and LC counterparts. A 2.4 GHz reference clock generator is implemented in a 0.18 μm standard CMOS process. While the temperature coefficient (TC) of the free‐running ROs is about 640 ppm/°C, the coupled structure offers a TC of 80 ppm/°C. Furthermore, the phase‐noise of the coupled structure is about 4 dB lower compared with the free‐running ROs. The proposed RO consumes about 2.8 mW and occupies a silicon area of 0.09 mm2.