bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGEMBANGAN SISTEM PENGAMAN PINTU LABORATORIUM ROBOTIKA UIN SULTAN SYARIF KASIM BERDASARKAN SIULAN BERBASIS SENSOR FC-04 DAN MIKROKONTROLER ATMEGA 328
Authors: Kharisma Oktaf Brillian , Putra Utama Hanif Burhanuddin 
Published: April 2022

Perkembangan teknologi berdampak positif bagi kehidupan manusia. Sistem rumah pintar yang sedang berkembang pesat dituntut agar dapat melayani konsumen. Sehingga, konsumen dapat merasakan keuntungan dari teknologi tersebut. Mengingat angka pencurian di Indonesia yang semakin meningkat dan perlunya sistem keamanan yang mampu bekerja terus menerus secara otomatis. Maka dari itu, dalam penelitian ini dikembangkan sebuah sistem pengaman kunci pintu otomatis sesuai dengan kondisi laboratorium robotika UIN Sultan Syarif Kasim. Berdasarkan pengujian yang telah dilakukan pada alat tersebut, maka dapat disimpulkan bahwa alat ini telah diuji dan dapat digunakan untuk membantu sistem keamanan pada pintu rumah berdasarkan intensitas suara dari siulan yang diterima oleh sensor suara FC -04 sebesar 91,1 dBA sampai 95,4 dBA.
Identifikasi Iris dengan Snake Model-PSO dan Gabor 2-D
Authors: Diatri Indradewi I Gusti Ayu Agung 
Published: April 2022

Pada penelitian ini dibangun sistem identifikasi biometrik iris dengan menggunakan metode Snake Model-PSO dan Gabor 2-D. Tahap-tahap yang dilakukan pada penelitian ini terdiri dari akuisisi citra, pre-processing, segmentasi, ekstraksi ciri, dan pengenalan. Metode Snake Model-PSO diterapkan dengan memanfaatkan koordinat titik pusat pupil yang telah ditemukan sebelumnya. Proses ekstraksi ciri dilakukan dengan menggunakan tapis Gabor 2-D berukuran 33×33 dan sudut orientasi bernilai 90º, 45º, 0º, dan -45º. Jumlah data referensi yang digunakan sebanyak 117 citra iris. Jumlah data uji yang digunakan sebanyak 78 citra iris. Berdasarkan hasil pengujian dapat disimpulkan bahwa persentase FMR sebesar 3,6737% dan FNMR sebesar 4,2735% untuk database iris kiri. Persentase FMR dan FNMR untuk database iris kanan menghasilkan yang sama, yakni 0%. Unjuk kerja sistem berdasarkan akurasi keputusan menghasilkan persentase terbaik sebesar 91, 0256% untuk database iris kiri dan 98,7179% untuk database iris kanan. Rata-rata waktu proses pada pendaftaran adalah 6,3109 detik, sedangkan pada identifikasi adalah 20,494 detik. Kata kunci: iris, Snake Model-PSO, Gabor 2-D, FMR, FNMR
Implementasi Application Programming Interface (API) Google Calendar Sebagai Reminder Informasi Kegiatan Pondok Pesantren
Authors: Sulastri Heni , Rahmatulloh Alam , Kurniawan Asep 
Published: April 2022

Masyarakat pada saat ini hampir seluruhnya memiliki akun di dunia maya, terutama akun Googlesebagai salah satu raksasa internet yang menyediakan berbagai macam fasilitas untuk memudahkan penggunanya, dengan fitur yang disediakan sebagai Application Programming Interface (API) yaitu API Google Calendarmerupakan salah satu fasiliitas yang digunakan untuk pengingat (reminder) dan penjadwalan kegiatan.Pondok Pesantren memiliki jadwal kegiatan dan informasi yang harus diketahui oleh anggota Pondok Pesantren sebagai pengetahuan dan panduan kegiatan belajar mengajar atau kegiatan lainya yang akan dilakukan. Pondok Pesantren ini jadwal kegiatan dan informasi dipublikasikan dengan cara manual, maka dibutuhkan suatu sistem yang mengelola jadwal kegiatan dan informasi, serta mempublikasikan menggunakan Google Calendaruntuk memberikan pengingat (reminder)atau notifikasi agar tersampaikan kepada anggota Pondok Pesantren. Penelitian ini menggunakan metodologi pengembangan sistem Personal Extreme Programming (PXP)dan hasil dari penelitian ini yaitu API Google Calendartelah berhasil diimplementasikan pada apliksi pesantren reminder, yang dapat mengelola kegiatan dan menyampaikan informasi kegiatan kepada anggota Pondok Pesantren menggunakan Google Calendar.
IDENTIFIKASI GEN PENYANDI PROTEIN TRANSPORT SEBAGAI KANDIDAT VAKSIN SUBUNIT TERHADAP BAKTERI Escherichia coli PENYEBAB DIARE WISATAWAN
Authors: Rasyid Burhannuddin , Karta I Wayan , Sari Ni Luh Putu Eka Kartika , Putra I Gusti Ngurah Dwija 
Published: April 2022

Diare masih menjadi masalah global dengan derajat kesakitan dan kematian yang tinggi di berbagai negara. Diare dapat menyerang wisatawan yang mengunjungi objek wisata di kawasan negara berkembang, termasuk Indonesia. Salah satu penyebab diare wisatawan adalah bakteri Escherichia coli pathogen yang memiliki gen penyandi protein transport yang berperan dalam patogenesis diare. Penelitian ini bertujuan untuk mengisolasi dan mengkarakterisasi gen penyandi protein transport sebagai kandidat vaksin subunit terhadap E. coli penyebab diare wisatawan.. Pengambilan sampel feses dilakukan di Ubud Care Clinic pada wisatawan yang melakukan pemeriksaan diare. Sampel dikultur pada media Eosin Metilen Blue, koloni tersangka kemudian diuji biokimia untuk mengkonfirmasi jenis bakteri yang ditemukan. Isolat positif E.coli selanjutnya disubkultur pada media Nutriet Broth, kemudian DNA E.coli diisolasi dengan GeneJET Genomic DNA Purification Kit. DNA hasil isolasi selanjutnya digunakan sebagai template reaksi PCR menggunakan pasangan primer yang mengenali gen aidA penyandi protein transport pada E.coli. Berdasarkan hasil kultur pada media EMB dan hasil uji biokimia pada media TSIA, SIM, Simon Citrat dan uji gula-gula didapatkan sebanyak 20 (59 %) dari 34 sampel feses penderita diare wisatawan positif bakteri E. coli. DNA dari 20 isolat E.coli berhasil diisolasi dengan ukuran sekitar 12000-13000 bp. Hasil PCR dari 20 sampel DNA bakteri E. coli terdapat 5 sampel positif mengandung gen aidA yang ditunjukkan dengan adanya pita DNA tunggal dengan ukuran sekitar 585 bp. Keberadaan gen aidA yang menyandi protein transport menunjukkan sifat patogenitas, yang membedakan antara E.coli pathogen dengan E.coli non-patogen
EVALUASI TATA KELOLA TEKNOLOGI INFORMASI DI DINAS KOMUNIKASI DAN INFORMATIKA MENGGUNAKAN FRAMEWORK COBIT 5
Authors: Hanif Asnita , Giatman M. , Hadi Ahmaddul 
Published: April 2022

Perkembangan teknologi dan informasi telah memberikan dampak terhadap organisasi, baik instansi swasta maupun pemerintahan, maka diperlukan evaluasi untuk memberikan saran dan masukan. Tujuan penelitian ini adalah untuk menganalisis keadaan tata kelola teknologi informasi di Dinas Komunikasi dan Informatika Kota Payakumbuh. Metode penelitian ini yakni deskriptif kualitatif, dengan subjek Dinas Komunikasi dan Informatika Kota Payakumbuh, dan objek penelitian ini adalah tingkat kapabilitas tata kelola teknologi dan informasi. Penelitian ini menggunakan framework COBIT 5 sebagai alat ukur model proses kapabilitas. Metode pengumpulan data yang digunakan adalah metode observasi dan studi literatur. Data yang telah diperoleh dianalisis menggunakan metode analisis statistik deskriptif kualitatif. Hasil pelenitian ini adalah proses DSS01 (Manage Operasional), DSS03 (Manage Problems) dan DSS05 (Manage Security Services) telah mencapai level 1 Performed Process karena atribut PA 1.1 mencapai kategori L. Simpulan penelitian ini adalah terdapat kelemahan dalam tata kelola dan manajemen teknologi dan informasi pada Dinas Komunikasi dan Informatika Kota Payakumbuh.
A Functional Equation with Biadditive Functions
Authors: Łukasik Radosław 
Published: May 2022

Abstract
Let S, H, X be groups. For two given biadditive functions A : S
2 → X, B : H
2 → X and for two unknown mappings T : S → H, g : S → S we will study the functional equation

B(T (x), T (y)) = A(x, g(y)), x, y ∈ S,

which is a generalization of the orthogonality equation in Hilbert spaces.
Effect of dietary β-Mannanase addition on performance, pododermatitis, and intestinal morphology as well as digesta Clostridium perfringens in broiler chickens: a pilot study
Authors: El-Wahab Amr Abd , ElMetwaly Ahmed Marwa Fawzy , Reckels Bernd , Schiel Benjamin , Visscher Christian , Kamphues Josef 
Published: May 2022

Abstract
This preliminary study was conducted to evaluate the effects of β-mannanase in diets of broilers on performance, pododermatitis, intestinal morphology, and digesta Clostridium perfringens counts. A total of 264 broilers (Ross 308) were randomly allotted to four treatments. A wheat-soybean based diet (CO) was supplemented with either 0.15 g xylanase/kg (XY), 0.15 g xylanase/kg + 110 mL β-mannanase/ton (MA1) or 0.15 g xylanase/kg + 220 mL β-mannanase/ton (MA2). At the end of the experiment, only significant differences in body weight were noted between groups fed MA1 and MA2 diets (2501 g vs 2641 g, respectively). Birds fed MA1 had significantly the lowest pododermatitis scores (2.26) compared to other groups. Ileal villus height measurements revealed that birds fed CO and MA2 diets had significantly higher values (1614 and 1651 µm, respectively) than those fed the MA1 diet (1489 µm). The positive percent of Clostridium perfringens in intestinal digesta at d 36 was significantly the highest in the XY group. Overall, although not improving performance, supplementing the diet with β-mannanase (110 mL/ton) contributed positively to foot pad health.
Surface, Elemental and Electrochemical Characterizations of Ancient Coins By Non – Destructive Techniques
Authors: Ion Rodica-Mariana , David Mădălina Elena , Gheboianu Anca Irina 
Published: April 2022

Abstract
The cultural heritage field represents a witness to artifacts values in a continuous evolution, it strongly influences our sense of identity and our behavior as people. To protect these archaeological treasures, different conservation and restoration methods are required. Considering the field of priceless artifacts, our research direction led us to preliminary studies of metallic coins from 20th century through non–destructive techniques. Copper–based coins were subjected to the surface characterization through optical microscopy (OM) in transmitted light, elemental composition analysis using Wavelength Dispersive X-ray Fluorescence (WDXRF) and electrochemical corrosion using Tafel extrapolarization technique. The microscopic investigations showed that the patina layer is due to presence of copper content in coins composition confirmed by X-ray fluorescence spectroscopy technique. Also, the electrochemical tests disclosed different corrosion rate according to each chemical composition of coins. This study provide a broad overview of ancient coins to preserve their value in the future.
Virtual Studies on the Behavior of Polyurethane on Mechanical Stresses
Authors: Negrea Alexis , Enescu Maria Cristiana , Stoian Elena Valentina , Petre Ivona 
Published: April 2022

Abstract
In this part of the paper, we will study the behavior of PUR polyurethane at different mechanical and thermal stresses, stresses for which this material behaves very well. It is known that this material behaves well as a protective material against shocks, so it is used as protection against mechanical elements. PUR behaves excellently at uneven static stresses and dynamic stresses. That is why it is used in the construction of the rollers of medium weight mobile devices or rollers that have cam functionality, strongly required for static and dynamic contact. PUR has very good thermal properties, it is used as a thermal insulator when it is in the form of high-density polyurethane foam (PUR / PIR).
Pyridoxamine alleviates high glucose induced fibrosis in renal tubular epithelial cell by inhibiting the activity of TGF-β1/Smad3 signaling pathway
Authors: Wang Ziqiang , Li Ying , Wang Ying , Zhao Kunxiao , Chi Yanqing , Wang Baoxing 
Published: April 2022

Abstract

Background
Renal fibrosis is one of the main characteristics of diabetic nephropathy. TGF-β1/Smad3 pathway is expected to reveal the pathogenesis of renal fibrosis in diabetic nephropathy (DN). Pyridoxamine (PM), a natural form of vitamin B6, is a powerful inhibitor of advanced glycation end products (AGEs). PM plays an anti-apoptotic, anti-oxidative stress, and fibrosis role in DN. The purpose of this study was to assess whether PM has a protective effect in renal tubular epithelial and to investigate its possible mechanism.

Methods
The effects of PM were investigated in HK-2 cells induced by high glucose. HK-2 cells were administered with PM at a dose of 1 mmol/L. Western blot and Realtime PCR were used to detect the expression levels of renal fibrosis related proteins. The possible mechanism of PM was examined by expression of transforming growth factor-β1 (TGF-β1)/Smad3 pathway.

Results
PM could reduce the expression of Fibronectin (FN) and α-smooth muscle actin (α-SMA) induced by high glucose. PM could also affect the activity of TGF-β1/Smad3 pathway in HK-2 cells. FN and α-SMA were up-regulated by overexpression of Smad3 for 48 h. After adding PM, the levels of FN and α-SMA are significantly decreased.

Conclusion
Our findings indicate that PM showed a protective effect in HK-2 cells through the inhibition of TGF-β1/Smad3 pathway.
The hydroperoxyl antiradical activity of Trolox in water: The effects of pH values on rate constants
Authors: Hoa Nguyen Thi 
Published: April 2022

Abstract
Trolox (6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid) is a highly hydrophilic α-tocopherol analog that is widely used as a standard against which the antioxidant ability of other chemicals is measured and represented in Trolox equivalents. However, the effect of pH values on the hydroxyl radical scavenging activity has not been fully studied yet. In this study, the HOO• antiradical activity of Trolox in water was studied. It was found that the H-abstraction of the O1-H bond determined the activity of the neutral and monoanion states, whereas the electron transfer reaction of the hydroxyl anion state determined the activity of the dianion state. Although the total rate constant increased following the increase in pH levels, the overall rate constant of the Trolox + HOO• reaction in water changed when pH levels rose due to the decrease in HOO• molar fraction. The results also revealed that at pH < 2, the O1-radical was the main intermediate of the Trolox + HOO• reaction in water, whereas, at pH ---gt--- 5, the anion-radical was the significant intermediate. Thus the rate constants and the reaction intermediates vary with the pH values.
Genetically modified mice for research on human diseases: A triumph for Biotechnology or a work in progress?
Authors: Brown Richard E. 
Published: April 2022

Abstract
Genetically modified mice are engineered as models for human diseases. These mouse models include inbred strains, mutants, gene knockouts, gene knockins, and ‘humanized’ mice. Each mouse model is engineered to mimic a specific disease based on a theory of the genetic basis of that disease. For example, to test the amyloid theory of Alzheimer’s disease, mice with amyloid precursor protein genes are engineered, and to test the tau theory, mice with tau genes are engineered. This paper discusses the importance of mouse models in basic research, drug discovery, and translational research, and examines the question of how to define the “best” mouse model of a disease. The critiques of animal models and the caveats in translating the results from animal models to the treatment of human disease are discussed. Since many diseases are heritable, multigenic, age-related and experience-dependent, resulting from multiple gene-gene and gene-environment interactions, it will be essential to develop mouse models that reflect these genetic, epigenetic and environmental factors from a developmental perspective. Such models would provide further insight into disease emergence, progression and the ability to model two-hit and multi-hit theories of disease. The summary examines the biotechnology for creating genetically modified mice which reflect these factors and how they might be used to discover new treatments for complex human diseases such as cancers, neurodevelopmental and neurodegenerative diseases.
Bredemolic acid restores glucose utilization and attenuates oxidative stress in palmitic acid-induced insulin-resistant C2C12 cells
Authors: Matee Karabo R. , Akinnuga Akinjide M. , Siboto Angezwa , Ngubane Phikelelani , Khathi Andile 
Published: April 2022

Abstract

Objective. Due to insulin resistance and oxidative stress that are associated with type 2 diabetes mellitus (T2DM), T2DM has become a prevalent metabolic disorder that presents various side effects. However, alternative antidiabetic treatment has commonly been used in treating diabetes mellitus in diabetic patients. In our previous studies, bredemolic acid has been reported as an antidiabetic agent that improves glucose uptake, ameliorates insulin resistance, and oxidative stress in the liver, heart, kidney, and skeletal muscle of prediabetic rats. However, these effects have not been validated in vitro. Therefore, this study was aimed to investigate the effects of bredemolic acid on insulin-mediated glucose utilization, lipid peroxidation, and the total antioxidant capacity (TOAC) in palmitic acid-induced insulin-resistant C2C12 skeletal muscle cells in vitro.

Methods. Insulin resistance was induced in the skeletal muscle cells after 4 h of exposure to palmitic acid (0.5 mmol/l). Different cell groups were incubated in culture media DMEM supplemented with fetal calf serum (10%), penicillin/streptomycin (1%), and L-glutamine (1%) and then treated with either insulin (4 µg/ml) or bredemolic acid (12.5 mmol/l) or with both. Thereafter, the cells were seeded in 24- or 96-well plates for determination of the cell viability, glucose utilization, glycogen formation, and antioxidant capacity.

Results. The results showed that bredemolic acid significantly improved TOAC and promoted glucose utilization via attenuation of lipid peroxidation and increased glycogen formation in the insulin-resistant cells, respectively.

Conclusion. This study showed that bredemolic acid restored the insulin resistance through improved glucose utilization, glycogen formation, and TOAC in the skeletal muscle cells.
Rheumatoid arthritis: current therapeutics compendium
Authors: Dariushnejad Hassan , Chodari Leila , Sedighi Mehrnoosh , Akbari Soheila , Ghorbanzadeh Vajihe 
Published: April 2022

Abstract
Rheumatoid arthritis is a common chronic inflammatory disease with substantial economic, social, and personal costs. Its pathogenesis is multifactorial and complex. The ultimate goal of rheumatoid arthritis treatment is stopping or slowing down the disease progression. In the past two decades, invention of new medicines, especially biologic agents, revolutionized the management of this disease. These agents have been associated with an improved prognosis and clinical remission, especially in patients who did not respond to traditional disease-modifying anti-rheumatic drugs (DMARDs). Improvement in the understanding of the rheumatoid arthritis pathogenesis leads to the development of novel biologic therapeutic approaches. In the present paper, we summarized the current therapeutics, especially biologic agents, available for the treatment of rheumatoid arthritis.
Measures to reduce stress in the workplace – results from focus group interviews with health professionals / Maßnahmen zur Reduktion von Stress am Arbeitsplatz – Resultate aus Fokusgruppeninterviews mit Gesundheitsfachpersonen
Authors: Golz Christoph , Renggli Fabienne Josefine , Gurtner Caroline , Peter Karin Anne 
Published: April 2022

Abstract

Introduction
Stress and poor working conditions can affect the health and satisfaction of health professionals. Until now, the perspective of the staff has not been sufficiently considered in the development of solutions. The aim was to capture the wishes and recommendations of health professionals that could contribute to an improvement of the work situation from their perspective.

Method
Semistructured focus group interviews with health professionals (nurses, midwifes, medical-technical-therapeutic professions and physicians) were conducted and analyzed using knowledge mapping and a deductive approach.

Results
Between June and November 2018, 128 health professionals from Swiss acute hospitals, psychiatric hospitals, nursing homes, and outpatient services participated in a total of 24 focus group interviews. They expressed the need to incorporate wishes into staff scheduling and to address vacation planning at an early stage. Other suggestions were to be able to take advantage of further training opportunities and to live a positive feedback and error culture, as well as to establish a clear division of roles and tasks.

Conclusions
The healthcare staff interviewed showed clear ideas about what should be improved to reduce workload. There is a great need for action in the general conditions as well as in leadership and management.
Bank-Specific and Macroeconomic Determinants of Bank Liquidity Creation: Evidence from MENA Countries
Authors: Mdaghri Anas Alaoui , Oubdi Lahsen 
Published: April 2022

Abstract
This study measures liquidity creation within a sample of 153 banks operating in 12 Middle Eastern and North African (MENA) countries from 2008 to 2017. We found that these banks created a total of $461.32 billion in liquidity in 2017, approximately 1.51 times the total liquidity created in 2008, mainly driven by commercial banks in Gulf Cooperation Council (GCC) countries. We also conducted an econometric analysis to investigate the internal and external factors affecting bank liquidity creation, applying a Fixed Effects model and the new Method of Moments Quantile Regression (MMQR). The results show that, among bank-specific factors, bank liquidity creation in MENA countries is related to capital, size, bank risk, deposits and profitability whilst market concentration does not appear to play a significant role. Regarding macroeconomic factors, inflation, unemployment, savings and monetary policy explain the variations in bank liquidity creation.
Adaptive Early Warning Systems: An Axiomatic Approach
Authors: Bhimjee Diptes C. P. 
Published: April 2022

Abstract
The U.S. Subprime Crisis and the subsequent Great Recession have highlighted a renewed interest in the proper design and implementation of Early Warning Systems (E.W.S.), in order to help deter the onset of subsequent extreme financial events, through the implementation of adequate crisis detection mechanisms. The present article describes the Adaptive Early Warning Systems (A.E.W.S.) axiomatic approach, as a natural operational extension to E.W.S. testing. This novel protocol upholds the operational dimension of implementing an efficient holistic crisis detection mechanism, a domain which has been hitherto overlooked by the E.W.S. literature. The paper first describes the major axiomatic principles sustaining the A.E.W.S. protocol, which seek to establish universal principles in support of the said protocol. Second, the article also describes a basic universal template for an A.E.W.S. surveillance platform, which duly describes how multiple testing procedures can be integrated into a single crisis detection framework, while targeting multiple segments of the financial markets (such as the conventional and non-conventional segments of the financial markets). Third, the paper also describes the major advantages and disadvantages associated with the implementation of this novel protocol. It is hoped that the effective implementation of the A.E.W.S. protocol as a novel operational framework in the global macroprudential toolkit might help deter the onset of future extreme financial events, by enabling a greater cohesiveness in E.W.S.-related central banking procedures, as well as promoting a greater international central banking cooperation prior to and during financial distress episodes.