bluuebunny/crossref_metadata_2025_split huggingface dataset:
Shifting narrative strategies: How monument advocates change their stories in response to conflict over time
Authors: Rupinsky Shae , Schomburg Madeline , Chandler Gabriel , Gelardi Carrington 
Published: October 2022

AbstractThis paper expands the Narrative Policy Framework (NPF) by employing an exploratory case study approach to examine the construction of narratives temporally. A large‐N Twitter dataset concerning the Bears Ears and Grand Staircase‐Escalante monuments controversy is utilized to examine the question: how does the use of narrative strategies change over time? Through the application of change‐point analysis, we determine time points of significant shifts towards use of the devil‐angel shift, scope of the conflict, and causal mechanism strategies. Overall, we find that organizations do not vary their use of narrative strategies over the course of a policy conflict but instead demonstrate discrete changes in response to certain policy events. Based on our findings, we conclude with suggestions for refining and expanding NPF hypotheses. Specifically, we recommend a more contextual analysis of shifts in narrative strategy use in response to specific events over time.
The Nordic governments' responses to the Covid‐19 pandemic: A comparative study of variation in governance arrangements and regulatory instruments
Authors: Christensen Tom , Jensen Mads Dagnis , Kluth Michael , Kristinsson Gunnar Helgi , Lynggaard Kennet , Lægreid Per , Niemikari Risto , Pierre Jon , Raunio Tapio , Adolf Skúlason Gústaf 
Published: October 2022

AbstractGovernment responses to the Covid‐19 pandemic in the Nordic states—Denmark, Finland, Iceland, Norway, and Sweden—exhibit similarities and differences. This article investigates the extent to which crisis policymaking diverges from normal policymaking within the Nordic countries and whether variations between the countries are associated with the role of expertise and the level of politicization. Government responses are analyzed in terms of governance arrangements and regulatory instruments. Findings demonstrate some deviation from normal policymaking within and considerable variation between the Nordic countries, as Denmark, Finland, and to some extent Norway exhibit similar patterns with hierarchical command and control governance arrangements, while Iceland, in some instances, resembles the case of Sweden, which has made use of network‐based governance. The article shows that the higher the influence of experts, the more likely it is that the governance arrangement will be network‐based.
‘The very wound of this ill news’: Maximilien Morillon and the impact of bad news during the early years of the Dutch Revolt, 1566–74
Authors: Baars Rosanne M. 
Published: October 2022

AbstractThis article demonstrates the importance that inhabitants of the sixteenth‐century Netherlands, in particular members of the elite, attached to the unpleasant effects of bad news, such as ill health, feelings of uncertainty, and discouragement. It aims to show this through the case study of the correspondence of Maximilien Morillon (1517–1586), vicar‐general of Mechelen and one of the most prolific letter writers from this period. Historians have conceded that the study of news and propaganda constitutes an essential part in understanding the dynamics of early modern conflicts. Yet while they have focused on the content of reports and methods of dissemination, little attention has been paid to the perceived effects of news on its recipients. Within the emotional turn, historians have studied early modern emotional states of grief, anxiety, and depression. Yet their connection with the study of news can arguably be made more explicit. In this article I will synthesize both areas of research, demonstrating how Morillon perceived the impact of bad news during the first years of the Dutch Revolt.
Flexible Domain Prediction using Mixed Effects Random Forests
Authors: Krennmair Patrick , Schmid Timo 
Published: October 2022

AbstractThis paper promotes the use of random forests as versatile tools for estimating spatially disaggregated indicators in the presence of small area-specific sample sizes. Small area estimators are predominantly conceptualised within the regression-setting and rely on linear mixed models to account for the hierarchical structure of the survey data. In contrast, machine learning methods offer non-linear and non-parametric alternatives, combining excellent predictive performance and a reduced risk of model-misspecification. Mixed effects random forests combine advantages of regression forests with the ability to model hierarchical dependencies. This paper provides a coherent framework based on mixed effects random forests for estimating small area averages and proposes a non-parametric bootstrap estimator for assessing the uncertainty of the estimates. We illustrate advantages of our proposed methodology using Mexican income-data from the state Nuevo León. Finally, the methodology is evaluated in model-based and design-based simulations comparing the proposed methodology to traditional regression-based approaches for estimating small area averages.
Two novel platelet biotinylation methods and their impact on stored platelet concentrates in a blood bank environment
Authors: Muret Charlotte , Crettaz David , Martin Agathe , Aliotta Alessandro , Bertaggia Calderara Debora , Alberio Lorenzo , Prudent Michel 
Published: October 2022

AbstractBackgroundStorage of platelet concentrates (PCs) has an impact on platelet quality and possibly affects their functions after transfusion. The influence of processing and storage conditions of PCs on their in vivo function upon transfusion is unknown. One option for investigating this question is to implement an ex vivo labeling of human platelets, to analyze them after transfusion into heathy volunteers and/or patients. In this study, we developed two labeling methods employing biotin.MethodsTwo methods of biotinylation were compared to a control (standard PC). The “Bio‐Wash” process used washing steps to label all platelets within the PC; for the other method, “Bio‐Direct,” one fifth of the PC were directly labeled without washing steps. The control and the two biotinylated PCs were analyzed over 7 days of storage. Labeling efficiency, platelet counts, phenotypes, and functions, along with time and costs, were evaluated to select the best process.ResultsBoth methods achieved a stable labeling through the storage, with similar platelet counts and metabolism in comparison to control PCs. Bio‐Wash showed higher activation phenotype and lower aggregation response in comparison to the Bio‐Direct method. The Bio‐Direct was performed within 1.5 h versus 3 h for the Bio‐Wash. However, the Bio‐Direct required 12 mg of biotin instead of 8 mg for the other process.ConclusionWe set up two methods of biotinylation that can be easily implemented in a blood bank environment. The Bio‐Direct process was preferred to the Bio‐Wash because of its similarity, from a functional and phenotypic point of view, with standard PCs.
ACVR and ECVDI consensus statement for the standardization of the abdominal ultrasound examination
Authors: Seiler Gabriela S. , Cohen Eli B. , d'Anjou Marc‐André , French John , Gaschen Lorrie , Knapp Stephanie , Salwei Rochelle M. , Saunders H Mark 
Published: October 2022

AbstractThis consensus statement is designed to provide a standard of care document and describes the ACVR and ECVDI definition for performing a standard abdominal ultrasound examination in dogs and cats. The ACVR and ECVDI define a standard abdominal ultrasonographic examination as a complete exam of the abdominal organs which is appropriately documented. The consensus statement intends to provide guidance to veterinary sonographers and veterinarians for the performance and documentation of high‐quality diagnostic ultrasound examination. The document may also serve as a teaching aid for veterinary students, veterinarians, and residents in diagnostic imaging who seek proficiency in diagnostic ultrasound. Finally, it may serve an additional role in educating the public as to what a high‐quality abdominal ultrasound examination should entail.
Estimation of the Daily Utilizability of a Flat Plate Solar Collector for Different Climatic Zones in Algeria
Authors: Smaili K. , Kasbadji Merzouk N. , Merzouk M. , Boukenoui R. 
Published: October 2022

Abstract
The essential aim of this study is to estimate the daily utilizability and useful energy of a flat-plate solar collector in Algeria for different climatic zones. For this purpose, a program based on Klein’s method was developed to estimate the daily utilizability and the useful energy characterized by the optical efficiency and the global loss coefficient that are equal to 0.72 and 7.9 W/m2K, respectively. The seasonal potentials of the whole studied zones are represented by geographical maps; then, a parametric study is performed to see the influence of the inlet temperature of the heat transfer fluid, the optical efficiency, and the global coefficient losses on the average utilizability per month for each site. Subsequently, the utilizability variations considering different sites and during various months are analyzed in terms of the average temperature of the heat transfer fluid, the optical efficiency, and the coefficient of global losses. The results show that the usable potential produced by this type of solar collector is 1500–1700 MJ/m2 in climatic zones E5 (Tanegrouft), E4 (Sahara), and E3 (Pre-Sahara) and is 1300 MJ/m2 in climatic zones E2 (Highlands) and E1 (Coastal) during the summer season. While for the winter season, the usable potential is 500–700 MJ/m2 in climatic zones E1 and E2, and 700–900 MJ/m2 in E3, E4, and E5, which can be considered the most favorable zones for the conversion of the available solar energy into thermal one through the flat-plate solar collector. The study of the effect on the system performance considering usability has shown that the effects of the overall loss coefficient are more significant compared to optical efficiency.
Tribo-Oxidation and Tribological Behavior of TaC–20%SiC Composites at Elevated Temperatures
Authors: Wu Zihao , Zhang Shubo , Chen Hao , Hai Wanxiu , Liu Meiling , Sun Wenzhou , Qin Falian 
Published: October 2022

Abstract
Tribo-oxidation mechanism and tribological behavior of TaC–20 vol%SiC composites from 25 to 800 °C coupled with aluminum oxide (Al2O3) and cemented carbide (WC–Co) were investigated. Tribo-oxidation products on the worn surface were analyzed by X-ray photoelectron spectroscopy (XPS). The results showed that as temperature increased from 25 °C to 800 °C, the specific wear-rates (WRs) of the composites decreased from 10−3 mm3N−1m−1 to 10−4 mm3N−1m−1 when coupled with Al2O3, while the WRs increased from 10−6 mm3N−1m−1 to 10−3 mm3N−1m−1 continuously when coupled with WC–Co. At 25 °C, TaC in the composite was partially oxidized into TaO2 as coupled with the two dualities. At 400 °C, the TaC in composite was oxidized into Ta2O5, while SiC was oxidized into SiCOx as coupled with Al2O3, while they were oxidized into Ta2O5 and SiO2−x as coupled with WC–Co. At 800 °C, the composites were oxidized into Ta2O5, SiCOx, and SiO2−x as coupled with the two dualities. The segregation of Ta compounds on the surface was promoted by friction. For the composites–Al2O3 tribo-pair, the wear mechanism changed from abrasion and adhesion at low temperature, to abrasion, adhesion, and tribochemical reaction (oxidation) at medium temperature, and adhesion and tribochemical reaction at high temperature. For composites–WC–Co tribo-pair, the wear mechanism was adhesion and tribochemical reaction in the whole temperature range.
A Model for Sound Propagation Through Corrugated Porous Structures With Mean Flow
Authors: Ronge Harshavardhan , Upalkar Shripad , Wagh Akshay , Choudhary Radhika , Krishnan Shankar , Ramamoorthy Sripriya 
Published: October 2022

Abstract
For applications of porous materials where mean pressure drop is a concern, packaging the material into a corrugated structure is better compared to other geometries such as block or wedge shapes. The goal of this study is to integrate noise reduction functionality within that material, which requires an understanding of sound propagation through corrugated porous structures, including flow effects. The corrugated porous structure involves porous partitions separating inlet and outlet fluid channels. The porous materials considered are periodic octet-truss and body-centered cubic unit cells, and sound propagation across these porous partitions is modeled using the Johnson–Champoux–Allard model. The predicted transmission loss (TL) is benchmarked using designed additively manufactured corrugated structures measured using a flow duct. The laminar flow regime is maintained across the porous structure to reduce flow-noise effects. It is shown that the TL for a given corrugated structure increases with a decrease in porosity, and the impact of flow becomes significant as the porosity decreases. The influence of flow on TL also depends on the unit cell configuration. Furthermore, the model provides insights into pressure and acoustic particle velocity distributions within the corrugated structure and reveals regions of the porous material that effectively participate in noise reduction.
Dynamic changes and prognosis of pulmonary congestion by lung ultrasound in hemodialysis patients: a systematic review and meta-analysis
Authors: Zhou Jianan , An Qi , Hou Xiukun 
Published: October 2022

Aims: Lung ultrasound (LUS) has been rapidly developed to evaluate pulmonary extravascular fluid. A systematic review was conducted to study the dynamic changes of LUS findings of pulmonary congestion before and after hemodialysis and examine the application of LUS for the prognosis of hemodialysis patients.Material and methods: This study searched online databases for articles on hemodialysis patients that used LUS to evaluate dynamic changes during hemodialysis or prognosis. Articles published in English or Chinese until September 2021 with ≥30 patients were included in this study.Results: Of the 1329 articles, 14 met the inclusion criteria: 9 reported dynamic changes during dialysis in LUS (438 patients), and 5 reported the prognosis of hemodialysis patients in LUS (1274 patients). As indicated by a further meta-analysis, eight studies found that the combined standardized effect size was -0.74. The all-cause mortality rate of the dialysis patient group with high B-line scores was three times that of the dialysis patient group with low B-line scores. In dialysis patients, no difference was found between the LUS guided treatment and the conventional care in reducing the all-cause mortality (HR=0.92 95%CI: 0.67-1.27) and cardiovascular events (HR=0.98 95%CI: 0.72 -1.34).Conclusions: LUS can be used to effectively evaluate the volume status of hemodialysis patients in real time. The level of B-line before dialysis is significantly correlated with the poor prognosis. However, compared with the routine nursing group, the treatment of hemodialysis patients with LUS-guided volume management cannot effectively reduce mortality and cardiovascular events.
Consistency of covid-19 trial preprints with published reports and impact for decision making: retrospective review
Authors: Zeraatkar Dena , Pitre Tyler , Leung Gareth , Cusano Ellen , Agarwal Arnav , Khalid Faran , Escamilla Zaira , Cooper Matthew Adam , Ghadimi Maryam , Wang Ying , Verdugo-Paiva Francisca , Rada Gabriel , Kum Elena , Qasim Anila , Bartoszko Jessica Julia , Siemieniuk Reed Alexander Cunningham , Patel Chirag , Guyatt Gordon , Brignardello-Petersen Romina 
Published: October 2022

ObjectiveTo assess the trustworthiness (ie, complete and consistent reporting of key methods and results between preprint and published trial reports) and impact (ie, effects of preprints on meta-analytic estimates and the certainty of evidence) of preprint trial reports during the covid-19 pandemic.DesignRetrospective review.Data sourcesWorld Health Organization covid-19 database and the Living Overview of the Evidence (L-OVE) covid-19 platform by the Epistemonikos Foundation (up to 3 August 2021).Main outcome measuresComparison of characteristics of covid-19 trials with and without preprints, estimates of time to publication of covid-19 preprints, and description of differences in reporting of key methods and results between preprints and their later publications. For the effects of eight treatments on mortality and mechanical ventilation, the study comprised meta-analyses including preprints and excluding preprints at one, three, and six months after the first trial addressing the treatment became available either as a preprint or publication (120 meta-analyses in total, 60 of which included preprints and 60 of which excluded preprints) and assessed the certainty of evidence using the GRADE framework.ResultsOf 356 trials included in the study, 101 were only available as preprints, 181 as journal publications, and 74 as preprints first and subsequently published in journals. The median time to publication of preprints was about six months. Key methods and results showed few important differences between trial preprints and their subsequent published reports. Apart from two (3.3%) of 60 comparisons, point estimates were consistent between meta-analyses including preprints versus those excluding preprints as to whether they indicated benefit, no appreciable effect, or harm. For nine (15%) of 60 comparisons, the rating of the certainty of evidence was different when preprints were included versus being excluded—the certainty of evidence including preprints was higher in four comparisons and lower in five comparisons.ConclusionNo compelling evidence indicates that preprints provide results that are inconsistent with published papers. Preprints remain the only source of findings of many trials for several months—an unsuitable length of time in a health emergency that is not conducive to treating patients with timely evidence. The inclusion of preprints could affect the results of meta-analyses and the certainty of evidence. Evidence users should be encouraged to consider data from preprints.
COVID-19 during pregnancy and risk of pregnancy loss (miscarriage or stillbirth): a systematic review protocol
Authors: Campbell Jennifer , Williams Rachael , Harley Mia , Bhaskaran Krishnan 
Published: October 2022

IntroductionThe COVID-19 pandemic has led to concerns about potential adverse pregnancy outcomes associated with infection, resulting in intensive research. Numerous studies have attempted to examine whether COVID-19 is associated with an increased risk of pregnancy loss. However, studies and reviews to date have drawn differing conclusions. The aim of this systematic review is to provide a summary of all quantitative research on the relationship between pregnancy loss and COVID-19 infection and, if appropriate, to synthesise the evidence into an overall effect estimate.Methods and analysisThree publication databases (Embase, PubMed and Cochrane) and four preprint databases (medRxiv, Lancet Preprint, Gates Open Research and Wellcome Open Research) will be searched. Boolean logic will be used to combine terms associated with pregnancy loss and COVID-19. The population of interest are pregnant women. Retrieved results will be assessed in two phases: (1) abstract screening and (2) full text evaluation. All studies which compare pregnancy loss outcomes in women who had COVID-19 versus those who did not quantitatively will be included. Narrative and non-English studies will be excluded. Two reviewers will screen independently, with results compared and discrepancies resolved by the study team. Study quality and risk of bias will be assessed using a quality appraisal tool. Results will be summarised descriptively and where possible synthesised in a meta-analysis.Ethics and disseminationThis systematic review requires no ethical approval. This review will be published in a peer-reviewed journal and provide an important update in a rapidly evolving field of research.PROSPERO registration numberCRD42022327437.
TiO2nanoparticles abrogate the protective effect of the Crohn’s disease-associated variation within the PTPN22 gene locus
Authors: Schwarzfischer Marlene , Niechcial Anna , Handler Kristina , Morsy Yasser , Wawrzyniak Marcin , Laimbacher Andrea S , Atrott Kirstin , Manzini Roberto , Baebler Katharina , Hering Larissa , Katkeviciutė Egle , Häfliger Janine , Lang Silvia , Keller Maja E , Woodtli Jérôme , Eisenbeiss Lisa , Kraemer Thomas , Schraner Elisabeth M , Wiesendanger Mahesa , Zeissig Sebastian , Rogler Gerhard , Moor Andreas E , Scharl Michael , Spalinger Marianne R 
Published: October 2022

ObjectiveInflammatory bowel disease (IBD) is a multifactorial condition driven by genetic and environmental risk factors. A genetic variation in the protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene has been associated with autoimmune disorders while protecting from the IBD subtype Crohn’s disease. Mice expressing the murine orthologous PTPN22-R619W variant are protected from intestinal inflammation in the model of acute dextran sodium sulfate (DSS)-induced colitis. We previously identified food-grade titanium dioxide (TiO2, E171) as a neglected IBD risk factor. Here, we investigate the interplay of the PTPN22 variant and TiO2-mediated effects during IBD pathogenesis.DesignAcute DSS colitis was induced in wild-type and PTPN22 variant mice (PTPN22-R619W) and animals were treated with TiO2nanoparticles during colitis induction. Disease-triggering mechanisms were investigated using bulk and single-cell RNA sequencing.ResultsIn mice, administration of TiO2nanoparticles abrogated the protective effect of the variant, rendering PTPN22-R619W mice susceptible to DSS colitis. In early disease, cytotoxic CD8+T-cells were found to be reduced in the lamina propria of PTPN22-R619W mice, an effect reversed by TiO2administration. Normalisation of T-cell populations correlated with increasedIfngexpression and, at a later stage of disease, the promoted prevalence of proinflammatory macrophages that triggered severe intestinal inflammation.ConclusionOur findings indicate that the consumption of TiO2nanoparticles might have adverse effects on the gastrointestinal health of individuals carrying the PTPN22 variant. This demonstrates that environmental factors interact with genetic risk variants and can reverse a protective mechanism into a disease-promoting effect.