bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maternal vaccination—current status, challenges, and opportunities
Authors: Kurasawa Kentaro 
Published: November 2022

AbstractAimMaternal vaccination is a promising strategy for protecting pregnant women and newborns against severe infections. This review aims to describe the current status and challenges associated with maternal vaccination against seasonal influenza, tetanus‐diphtheria‐pertussis (Tdap/DTaP), and novel coronavirus disease of 2019 (COVID‐19) in Japan and other countries, mainly the United States and the United Kingdom.MethodsA literature search was conducted in PubMed and other public websites (e.g., Centers for Disease Control and Prevention) to obtain information on maternal vaccination.ResultsInactivated vaccines are recommended for pregnant women by gynecologic societies in Japan, the United States, and the United Kingdom. Among pregnant Japanese women, the influenza and COVID‐19 (two doses) vaccine coverage rates were 27.0%–53.5% (six studies) and 73.6% (one study), respectively; there are no studies on maternal vaccination with DTaP. Concerns regarding vaccine safety are a major barrier to maternal vaccination across countries. Maternal vaccination is effective in preventing severe disease in pregnant women and protecting infants aged <6 months, is generally safe, and does not increase the risk of adverse maternal and fetal outcomes. Providing accurate information regarding vaccination through healthcare providers and the government and government funding for vaccines may help improve maternal vaccination rates in Japan.ConclusionCurrent coverage for maternal vaccination is still low globally mainly because of vaccine hesitancy among pregnant women. The government, drug‐regulatory authorities, and healthcare professionals must educate pregnant women about the effectiveness and safety of maternal vaccines and encourage vaccination when the benefits outweigh the risks.
Fetal heart rate patterns complicated by chorioamnionitis and subsequent cerebral palsy in Japan
Authors: Yamaguchi‐Goto Tomoko , Ohashi Masanao , Kodama Yuki , Sameshima Hiroshi 
Published: November 2022

AbstractAimThis retrospective study was performed to investigate whether certain fetal heart rate patterns were associated with subsequent cerebral palsy (CP) in infants with chorioamnionitis at or near term.MethodsWe used cases registered by the Japan Obstetric Compensation System for CP, which is a nationwide population‐based database. Among them, 133 infants with chorioamnionitis who were born at ≥34 weeks of gestation were enrolled. All infants underwent magnetic resonance imaging (MRI), and all fetal heart rate charts had been interpreted according to the National Institute of Child Health and Human Development criteria, focusing on antepartum and immediately before delivery.ResultsThe incidence of CP after chorioamnionitis at ≥34 weeks of gestation was 0.3 per 10 000 in Japan. Between the clinical (24%) and subclinical groups (76%), the incidence of abnormal fetal heart rate patterns did not differ. According to the MRI classification, 88% of the infants with CP showed hypoxic–ischemic encephalopathy. Half of the infants with CP experienced terminal bradycardia, leading to severe acidosis and exclusively to hypoxic–ischemic encephalopathy. In another half, who did not experience bradycardia, 80% had moderate acidosis (pH 7.00–7.20) resulting in hypoxic–ischemic encephalopathy, and the remaining 20% showed non‐acidosis resulting in brain damage other than hypoxic–ischemic encephalopathy. The fetal heart rate patterns before the terminal bradycardia showed that the incidence rates of late deceleration or decreased variability were high (>60%).ConclusionFifty percent of pregnant women with chorioamnionitis‐related CP had terminal bradycardia that exclusively resulted in hypoxic–ischemic encephalopathy.
Mental Maps of Eastern Europe: States, Mentalities, Modernisation
Authors: Varga Mihai 
Published: November 2022

AbstractEastern Europe has been the object of orientalising discourses portraying it as a region defined by problematic statehood, underdevelopment, and nationalist‐religious warmongering. These discourses have produced 19th‐century mental maps of Europe contrasting a perceived ‘core’ European area ending with the Frankish Empire's eastern border and coinciding with later Enlightenment influence and an indistinct ‘Orient’ or ‘East’, bypassed by “modernising” processes. This contribution focuses on (post‐)Cold War discourses in social science and shows how these discourses re‐produce 19th‐century layers of orientalising map‐making and keep East‐West differences alive by tracing deficient, fragile or repressive state institutions back to alleged Eastern European ‘mentalities’.
Protein foods from animal sources and risk of nonalcoholic fatty liver disease in representative cohorts from North and South China
Authors: Zhang Shunming , Yan Yan , Meng Ge , Zhang Qing , Liu Li , Wu Hongmei , Gu Yeqing , Wang Xuena , Zhang Juanjuan , Sun Shaomei , Wang Xing , Zhou Ming , Jia Qiyu , Song Kun , Borné Yan , Qi Lu , Chen Yu‐Ming , Niu Kaijun 
Published: November 2022

AbstractBackgroundEmerging evidence suggests that animal protein foods may increase the risk of nonalcoholic fatty liver disease (NAFLD). We therefore examined the NAFLD risk reduction related to substituting plant protein foods for animal protein foods.MethodsThe cohort in North China included 14,541 participants from the Tianjin Chronic Low‐Grade Systemic Inflammation and Health (TCLSIH) study, and the cohort in South China included 1297 participants from the Guangzhou Nutrition and Health Study (GNHS). Dietary intake was assessed using validated food frequency questionnaires. NAFLD was ascertained by abdominal ultrasound. The Cox model was used to fit the substitution analysis.ResultsIn the TCLSIH cohort, when replacing one type of animal protein food (eggs, processed meat, unprocessed red meat, poultry, and fish) with an equivalent serving of plant protein foods (nuts, legumes, and whole grains), the replacement of animal protein foods with whole grains showed the strongest benefit; substituting one serving per day of whole grains for an equal amount of eggs (hazard ratio [HR] = 0.89; 95% confidence interval [CI]: 0.79, 1.00), processed meat (HR = 0.76; 95% CI: 0.64, 0.91), unprocessed red meat (HR = 0.90; 95% CI: 0.81, 1.00), poultry (HR = 0.81; 95% CI: 0.72, 0.92), or fish (HR = 0.87; 95% CI: 0.78, 0.97) was associated with a lower risk of NAFLD. In both the TCLSIH and GNHS cohorts, replacing poultry with fish, nuts, legumes, or whole grains was associated with a lower risk of NAFLD. When different numbers of protein foods were simultaneously replaced, the risk reduction of NAFLD was stronger.ConclusionsOur findings suggest that replacing animal protein foods with plant protein foods is related to a significant reduction in NAFLD risk.
The ‘legal’ in socio‐legal history: Woods and Pirie v. Cumming Gordon
Authors: DERRY CAROLINE 
Published: November 2022

AbstractThis article explores the Scottish defamation case Woods and Pirie v. Cumming Gordon (1810–1812) in order to demonstrate the value of legal readings across the broadest spectrum of socio‐legal history. While the case has attracted attention from social historians, particularly historians of sexuality, it was shrouded in secrecy and thus did not contribute to the development of legal doctrine. Nonetheless, careful attention to the specifically legal nature of the archive and proceedings deepens our understanding of them and their social implications. Woods and Pirie concerned an allegation of lesbianism made by a half‐Indian, half‐Scottish schoolgirl against her teachers. Its extensive records offer particularly rich material relating to gender, sexuality, race, nationality, and empire, the significance and limitations of which are only fully grasped if it is analysed with an understanding of its legal context. Ultimately, such engagements also expand our knowledge of the law's operation.
Just noticeable difference in sweetness perception of cola: Small changes in sugar are noticeable
Authors: Valicente Vinicius M. , Sharpe Kassidy B. , Gletsu‐Miller Nana , Running Cordelia A. 
Published: November 2022

AbstractSugar‐sweetened beverage consumption contributes to obesity and related diseases. Fortunately, beverages with reduced sweetness are a growing category in the beverage industry. These lower sweetness products could be useful for reducing the total dietary intake of sugar, but publicly available data are sparse on how much sweetness can be reduced without the change becoming noticeable to consumers. We investigated the just noticeable difference (JND) in sweetness of a cola‐flavored carbonated beverage. Two sensory tests were conducted to detect the JND from 12.00% w/w sucrose. In each test, we used cola‐flavored seltzer water with five decreasing sucrose concentrations (test 1:8.02–12.00% w/w; test 2:10.21–12.00% w/w). In both tests, samples were paired with the 12.00% reference, and participants were instructed to identify the sweeter sample. Participants correctly identified the reference sample at 10.21% in test one (p = .0039) and at 10.89% (p = .014) in test two. The data indicate that in a cola beverage, sucrose can be reduced by ~9.25% of the original concentration (12.00–10.89% w/w) before the sweetness becomes apparent to consumers. However, further work should consider whether sugar reductions greater than 9.25% would be acceptable, even if the difference in sweetness is apparent.Practical ApplicationsThese data could help researchers and industry product developers know how much sugar can be reduced from a cola‐flavored beverage before the change is apparent to consumers.
Continuous light exposure influences luteinization and luteal function of ovary in ICR mice
Authors: Li Xiao‐Long , Zhu Hai‐Jing , Zhang Qin , Li Yong‐Shi , Li Yan‐Chu , Feng Xie , Yuan Rui‐Ying , Sha Qian‐Qian , Ma Jun‐Yu , Luo Shi‐Ming , Sun Qing‐Yuan , Chen Lei‐Ning , Ou Xiang‐Hong 
Published: November 2022

AbstractWith the rapid change of people's lifestyle, more childbearing couples live with irregular schedules (i.e., staying up late) and suffer from decreased fertility and abortion, which can be caused by luteal phase defect (LPD). We used continuous light‐exposed mice as a model to observe whether continuous light exposure may affect luteinization and luteal function. We showed that the level of progesterone in serum reduced (p < .001), the number of corpus luteum (CL) decreased (p < .01), and the expressions of luteinization‐related genes (Lhcgr, Star, Ptgfr, and Runx2), clock genes (Clock and Per1), and Mt1 were downregulated (p < .05) in the ovaries of mice exposed to continuous light, suggesting that continuous light exposure induces defects in luteinization and luteal functions. Strikingly, injection of melatonin (3 mg/kg) could improve luteal functions in continuous light‐exposed mice. Moreover, we found that, after 2 h of hCG injection, the level of pERK1/2 in the ovary decreased in the continuous light group, but increased in the melatonin administration group, suggesting that melatonin can improve LPD caused by continuous light exposure through activating the ERK1/2 pathway. In summary, our data demonstrate that continuous light exposure affects ovary luteinization and luteal function, which can be rescued by melatonin.
Computed tomographic findings in dogs with suspected aspiration pneumonia: 38 cases (2014‐2019)
Authors: Constantinescu R. , Istrate A. , Sumping J. C. , Dye C. , Schiborra F. , Mortier J. R. 
Published: November 2022

ObjectivesTo describe computed tomographic (CT) findings in dogs diagnosed with aspiration pneumonia and to assess for any correlation with patient outcome.Materials and MethodsRetrospective analysis of 38 cases with a presumptive diagnosis of aspiration pneumonia at two UK referral centres. Medical records were reviewed for signalment, history, physical examination and clinicopathologic data. CT examinations of the thorax were reviewed by the European College of Veterinary Diagnostic Imaging board‐certified radiologist for all dogs to describe the characteristics and distribution of the pulmonary lesions.ResultsThe most common CT findings were lung lobe consolidation associated with air bronchograms (100%) followed by ground‐glass attenuation (89.4%), bronchial wall thickening (36.8%), bronchiolectasis (31.5%) and bronchiectasis (15.7%). Large‐breed dogs were overrepresented. Duration of hospitalisation ranged between 0 and 8 days (mean 3 days). Overall, 89.4% of dogs survived the aspiration event and were discharged from the hospital. The four dogs that did not survive to discharge had five or more lobes affected on CT.Clinical SignificanceCT findings in dogs with aspiration pneumonia are described. CT is a useful imaging modality to diagnose aspiration pneumonia.
Recovery of Salmonella bacterial isolates from pooled fecal samples from horses
Authors: Goni Jose I. , Hendrix Kenitra , Kritchevsky Janice 
Published: November 2022

AbstractBackgroundIt is important to determine if a horse is shedding Salmonella spp., but a complete culture series can be cost prohibitive.ObjectivesDetermine the optimal pooling technique to maintain high sensitivity of Salmonella spp. culture using spiked samples, and then demonstrate the efficacy of this protocol on clinical submissions.HypothesisPooled fecal samples are as sensitive as 5 individual cultures for the detection of Salmonella shedding.AnimalsA single Salmonella‐negative horse from the university herd, and 19 hospitalized horses.MethodsSalmonella‐free fecal samples were spiked with different amounts of Salmonella spp. (102, 103, 104, and 105 colony forming units [cfu]) and homogenized to evaluate pooled samples. Five individual fecal samples were collected from 19 hospitalized horses. Ten‐gram aliquots of each individual sample were combined to make a pooled sample. Both individual and pooled samples were cultured for Salmonella spp. The identity of bacterial isolates was confirmed by matrix‐assisted laser desorption‐ionization time of flight mass spectrometry.ResultsA 102 cfu concentration of Salmonella spp. could be recovered from a spiked Salmonella‐free fecal sample. Homogenization protocols indicated that the addition of 20 mL of broth to the pooled sample improved recovery, whereas homogenization time did not. Of the 19 horses tested, 5 were positive for Salmonella. In all instances, Salmonella spp. were recovered from the fecal pool as well as individual samples.Conclusions and Clinical ImportancePooling of 5 fecal samples for Salmonella culture is a sensitive and cost‐effective diagnostic approach to detect horses that are shedding the organism.
Society for Medical Anthropology Statement on Supreme Court Dobbs v. Jackson Women's Health Organization Decision
Authors: Buchbinder Mara , Mishtal Joanna , Singer Elyse O. , Wendland Claire L. 
Published: November 2022

AbstractThis statement summarizes key findings from anthropological and related scholarship on the harmful consequences of inadequate abortion access, leading the Society for Medical Anthropology to register profound concern about the recent Supreme Court decision inDobbs v. Jackson. After circulation to SMA members for input, a finalized version passed a membership vote by an overwhelming margin. This statement complements one produced by the Council for Anthropology and Reproduction,available here.
Towards automatic detection and classification of orca (Orcinus orca) calls using cross‐correlation methods
Authors: Palmero Stefano , Guidi Carlo , Kulikovskiy Vladimir , Sanguineti Matteo , Manghi Michele , Sommer Matteo , Pesce Gaia 
Published: November 2022

AbstractOrcas (Orcinus orca) are known for complex vocalization. Their social structure consists of pods with unique call repertoires and clans sharing vocal traditions. Call repertoires are typically established visually and aurally and are used for pod identification. Automatic tools are, however, more suited for large data sets. An Icelandic orca pod occurring in 2019 in the Ligurian Sea provided a unique occasion for collecting recordings of an isolated pod in natural conditions. Recordings were analyzed visually and aurally to create a pod catalog. The R package “warbleR” was used for the first time on a small subsample of orca data to automatically detect sound samples and classify sound types. We found cross‐correlation methods with the Pearson correlation coefficient (PCC) to successfully classify sound types, though false positives occur. We compared our catalog to Icelandic and Antarctic ones checking for similarities and dissimilarities. We found five matches in the Icelandic catalog, two of which had high PCCs ranges (0.62–0.67; 0.60–0.65). Our automatic approach was limited by background noise and variability of orca vocalizations, and it was computationally demanding. We show cross‐correlation methods with the PCC can be a powerful tool to verify audio‐visual repertoire matches between orca from different regions.
Turnip crinkle virus‐encoded suppressor of RNA silencing interacts with Arabidopsis SGS3 to enhance virus infection
Authors: Liu Linyu , Wang Haiyan , Fu Yan , Tang Wen , Zhao Pingjuan , Ren Yanli , Liu Zhixin , Wu Kunxin , Zhang Xiuchun 
Published: November 2022

AbstractMost plant viruses encode suppressors of RNA silencing (VSRs) to protect themselves from antiviral RNA silencing in host plants. The capsid protein (CP) of Turnip crinkle virus (TCV) is a well‐characterized VSR, whereas SUPPRESSOR OF GENE SILENCING 3 (SGS3) is an important plant‐encoded component of the RNA silencing pathways. Whether the VSR activity of TCV CP requires it to engage SGS3 in plant cells has yet to be investigated. Here, we report that TCV CP interacts with SGS3 of Arabidopsis in both yeast and plant cells. The interaction was identified with the yeast two‐hybrid system, and corroborated with bimolecular fluorescence complementation and intracellular co‐localization assays in Nicotiana benthamiana cells. While multiple partial TCV CP fragments could independently interact with SGS3, its hinge domain connecting the surface and protruding domains appears to be essential for this interaction. Conversely, SGS3 enlists its N‐terminal domain and the XS rice gene X and SGS3 (XS) domain as the primary CP‐interacting sites. Interestingly, SGS3 appears to stimulate TCV accumulation because viral RNA levels of a TCV mutant with low VSR activities decreased in the sgs3 knockout mutants, but increased in the SGS3‐overexpressing transgenic plants. Transgenic Arabidopsis plants overexpressing TCV CP exhibited developmental abnormalities that resembled sgs3 knockout mutants and caused similar defects in the biogenesis of trans‐acting small interfering RNAs. Our data suggest that TCV CP interacts with multiple RNA silencing pathway components that include SGS3, as well as previously reported DRB4 (dsRNA‐binding protein 4) and AGO2 (ARGONAUTE protein 2), to achieve efficient suppression of RNA silencing‐mediated antiviral defence.
Professionalising care into compliance: The challenge for personalised care models
Authors: Cole Clare , Mummery Jane , Peck Blake 
Published: November 2022

AbstractOne of the most basic understandings of nursing is that a nurse is a caregiver for a patient who helps to prevent illness, treat health conditions, and manage the physical needs of patients. Nursing is often presented as a caring profession, which provides patient care driven by ideals of empathy, compassion and kindness. These ideals of care have further been foregrounded through the development and implementation of stress on patient centred care (PCC) and/or person‐centred practice (PCP). Although the idealisation of nursing as a caring profession is common, and one certainly seen as integral by nurses and written into the heart of regulatory documentation, we contend that the actual delivery of care is being undercut by the very regulatory climate that strives to professionalise care. As we outline, with specific reference to the context of Australian Nursing, this transformation delivers a commodified, even McDonaldized, model of patient management rather than care. It seems that even with its explicit stress on PCC and PCP, Australian Nursing cannot live up to its own care ideals. Having outlined this problem, the paper then demonstrates the ways in which PCC is thwarted at the coal face of nursing practice and that there must be an institutionalised change to be able to provide genuine patient‐centred care.
Radiation‐induced osteosarcoma involving the mandible—Report of a rare diagnosis
Authors: Mahmood Hanya , Hankinson Paul , Andrew David , Nusrath Muzzammil , Khurram Syed Ali 
Published: November 2022

AbstractBackgroundRadiation‐induced osteosarcomas of the jaws are a rare but often fatal consequence of radiation therapy in the head and neck region. Here we present a case of radiation‐induced osteosarcoma of the mandible.Case PresentationA male presented with severe trismus and marked left lingual alveolus expansion 1 year following extractions in the lower left quadrant. Four years previously, he had radical radiotherapy (70Gy) and chemotherapy for a p16‐positive T1N2cM0 squamous cell carcinoma of the left tonsil with a positive left level II node. Initial bone biopsies of the left mandible showed a bony sequestrum suggestive of osteoradionecrosis with the presence of abnormal osteoid suspicious of osteosarcoma. Imaging demonstrated an abnormal exophytic bone‐forming lesion in the left mandibular body and parasymphysis and ruled out a metastatic lesion. The patient underwent bilateral neck dissection, left mandibulectomy with fibula flap reconstruction and full‐thickness skin graft.ConclusionsOsteosarcoma should be considered if changes are seen in previously stable irradiated bone with bony destruction and a soft tissue mass. This case highlights the importance of synthesis of clinical, radiological and pathological findings in the diagnosis of such lesions, especially where the histology initially suggested a benign process.
Significance of mitral L‐waves in predicting late recurrences of atrial fibrillation after radiofrequency catheter ablation
Authors: Wada Ryo , Shinohara Masaya , Fujino Tadashi , Matsumoto Shingo , Yao Shintaro , Yano Kensuke , Dobashi Shintaro , Akitsu Katsuya , Koike Hideki , Ohara Hiroshi , Kinoshita Toshio , Yuzawa Hitomi , Nakanishi Rine , Ikeda Takanori 
Published: November 2022

AbstractBackgroundThe mitral L‐wave, a prominent mid‐diastolic filling wave in echocardiographic examinations, is associated with severe left ventricular diastolic dysfunction. The relationship between the mitral L‐wave and outcome of catheter ablation (CA) in patients with atrial fibrillation (AF) has not been established. This study aimed to evaluate the predictive value of mitral L‐waves on AF recurrence after CA.MethodsThis was a retrospective and observational study in a single center. One hundred forty‐six patients (mean age; 63.9 [56.0–72.0] years, 71.9% male) including 66 non‐paroxysmal AF patients (45.2%) who received a first CA were enrolled. The mitral L‐waves were defined as a distinct mid‐diastolic flow velocity with a peak velocity ≥20 cm/s following the E wave in the echocardiographic examinations before CA. The patients enrolled were divided into groups with (n = 31, 21.2%) and without (n = 115, 78.8%) mitral L‐waves. Univariate and multivariate analyses were carried out to determine the predictive factors of late recurrences of AF (LRAFs), which meant AF recurrence later than 3 months after the CA.ResultsDuring a follow‐up of 28.8 (15.0–35.8) months, the ratio of LRAFs in patients with mitral L‐waves was significantly higher than that in those without mitral L‐waves (15 [46.9%] vs. 16 [14.0%], p < .001). A multivariate analysis using a Cox proportional hazard model revealed that the mitral L‐waves were a significant predictive factor of LRAFs (hazard ratio: 3.09, 95% confidence interval: 1.53–6.24, p = .002).ConclusionThe appearance of mitral L‐waves could predict LRAFs after CA.