bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk of adenoma recurrence after polypectomy in patients younger than 50 years vs. 50 years old and over with diminutive or small adenomas
Authors: Cai Sicheng , Shi Huiying , Fan Mengke , Zhang Qin , Lin Rong 
Published: October 2022

Background and aimsCurrent studies have shown that polyp recurrence occurs after colonic adenomas polypectomy (AP), but the difference in recurrence risk between patients in patients older than 50 years and younger than 50 years has not been clearly studied.Methods490 patients after AP were enrolled in the study. The patients were classified according to age (&lt;50 years old or ≥50 years old), and then further categorized according to the baseline adenoma characteristics: Group 1: 1–2 non-advanced adenomas (NAAs) 1–5 mm in size; Group 2: ≥3 NAAs, 1–5 mm; Group 3: 1–2 NAAs, 6–9 mm; Group 4: ≥3 NAAs, 6–9 mm; and Group 5: advanced adenomas.ResultsDuring a mean follow-up interval of 2.52 years (2.51 years for ≥50 years old and 2.55 years for patients &lt;50 years old), NAA recurrence was detected in 147 patients (30.0%). Overall, the hazard ratio (HR) for NAA recurrence after AP was higher in patients ≥50 years old than that in patients &lt;50 years old (HR, 1.774, P = 0.003). For patients &lt;50 years old, HRs (Group 2-5 vs. G1, respectively) for NAA recurrence were 0.744 (P = 0.773), 3.885 (P = 0.007), 5.337 (P = 0.003), and 3.334 (P = 0.015). For patients ≥50 years old, HRs (Group 2-5 vs. G1, respectively) for NAA recurrence were 1.033 (P = 0.965), 1.250 (P = 0.405), 2.252 (P = 0.015), and 1.887 (P = 0.009). For G1, the risk of NAA recurrence was significantly higher in patients ≥50 years old (HR, 2.932, P = 0.011) than that in patients &lt;50 years old; for G2–G5, the risk was similar in the two age groups (P &gt; 0.05).ConclusionsFor patients &lt;50 years old with less than 3 NAAs that are 1–5 mm in size, the recurrence rate of NAA is less than that of patients ≥50 years old with the same index colonoscopy findings. When the adenomas are ≥5 mm, or their number exceeds 3, they have similar recurrence risk as that for patients ≥50 years old.
Predictive value of C-reactive protein levels for the early and later detection of postoperative complications after cytoreductive surgery and HIPEC
Authors: Roux Alexia , David Valentin , Bardet M Sylvia , Auditeau Emilie , Durand Fontanier Sylvaine , Taibi Abdelkader 
Published: October 2022

SynopsisC-reactive protein (CRP), white blood cells and procalcitonin (PCT) participate in the systemic response to inflammation and increase after postoperative infective complications. Postoperative complications after CRS and HIPEC could be predicted using the CRP cut-off value (169 mg/L at PODs 3-5 and 62 mg/L at PODs 7-10).BackgroundPostoperative elevation of C-reactive protein (CRP) can be used in order to predict the postoperative complications in many indications. Cytoreduction surgery (CRS) associated with hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with high morbidity.ObjectivesThe aim of the study was to demonstrate the CRP predictive value for the occurrence of complications.MethodsAll patients who had CRS and HIPEC, regardless of the origin of peritoneal metastasis, were included in this retrospective study. Postoperative complications and CRP and white blood cell (WBC) counts were recorded from postoperative day (POD) 1 through 10.ResultsAmong the 127 patients included, 58 (45.7%) had no complications (NCs), 53 (41.7%) had infective complications (ICs), and 16 (12.6%) had non-infective complications (NICs). The IC group had a higher CRP value than the NC group, which was statistically significant from POD7 to POD10 (41.1 versus 107.5 p = 0.023 and 77.8 versus 140 p = 0.047, respectively). A cut-off CRP value was 169 mg/L at PODs 3-5 and 62 mg/L at PODs 7-10. The area under the curve (AUC) at POD5 was 0.56 versus 0.76 at POD7, p=0.007. The sensibility, specificity, positive and negative predictive values of these cut-offs were 55%, 83%, 74% and 67%, respectively. Moreover, 17 patients (32%) with ICs had a CRP value higher than these cut-offs before the diagnosis was made by the medical team.ConclusionThis study suggested that postoperative complications could be predicted using the CRP cut-off value on PODs 3-5 (169 mg/l) and PODs 7-10 (62 mg/l) after CRS and HIPEC.
Three-dimensional ultrasound integrating nomogram and the blood flow image for prostate cancer diagnosis and biopsy: A retrospective study
Authors: Chen Dong , Niu Yingjie , Chen Haitao , Liu Dequan , Guo Rong , Yao Nan , Li Zhiyao , Luo Xiaomao , Li Hongyang , Tang Shicong 
Published: October 2022

BackgroundsProstate cancer (PCa) is the second most common male cancer in the world and based on its high prevalence and overwhelming effect on patients, more precise diagnostic and therapeutic methods are essential research topics. As such, this study aims to evaluate the value of three-dimensional transrectal ultrasound (3D-TRUS) in the detection, diagnosis and biopsy of PCa, and to provide a basis for clinical practice of PCa.MethodsRetrospective analysis and comparison of a total of 401 male patients who underwent prostate TRUS in our hospital from 2019 to 2020 were conducted, with all patients having prostate biopsy. Nomogram was used to estimate the probability of different ultrasound signs in diagnosing prostate cancer. The ROC curve was used to estimate the screening and diagnosis rates of 3D-TRUS, MRI and TRUS for prostate cancer.ResultsA total of 401 patients were randomly divided into two groups according to different methods of prostate ultrasonography, namely the TRUS group (251 patients) and the 3D-TRUS group (150 patients). Of these cases, 111 patients in 3D-TRUS group underwent MRI scan. The nomogram further determined the value of 3D-TRUS for prostate cancer. The ROC AUC of prostate cancer detected by TRUS, MRI and 3D-TRUS was 0.5580, 0.6216 and 0.6267 respectively. Biopsy complications were lower in 3D-TRUS group than TRUS group, which was statistically significant (P&lt;0.005).ConclusionsThe accuracy of 3D-TRUS was higher in diagnosis and biopsy of prostate cancer. Meanwhile, the positive rate of biopsy could be improved under direct visualization of 3D-TRUS, and the complications could be decreased markedly. Therefore, 3D-TRUS was of high clinical value in diagnosis and biopsy of prostate cancer.
The moderating effect of alexithymia on the relationship between stress and cyberchondria
Authors: Zhou Yi , Dai Lisha , Deng Yunlong , Zeng Hongling , Yang Lifeng 
Published: October 2022

ObjectivesThe pandemic has increased the level of perceived stress and provided a fertile soil for Cyberchondria. This study aims to investigate the relationship between stress, cyberchondria, and alexithymia.MethodsThis cross-sectional study used convenience sampling to carried out on a total 1,117 college students (female/male:536/581; mean age: 19.95 ± 1.32). Cyberchondria Severity Scale (CSS), Toronto Alexithymia Scale (TAS) and Short Depression Anxiety Stress Scales (DASS-21) were used to assessed the present study variables.ResultsSignificant differences emerged for CSS scores by gender (t = 3.74, p &lt; 0.01) and had any comorbid disease (t = 2.47, p &lt; 0.05), The Pearson correlation showed Cyberchondria has a significant positive correlation with stress and alexithymia (r = 0.50, p &lt; 0.01, r = 0.36, p &lt; 0.01). Furthermore, the regression analysis described that stress (β = 0.50, p &lt; 0.01) and alexithymia (β = 0.36, p &lt; 0.01) were the significant positive predictors of cyberchondria. Moreover, moderation analysis showed that alexithymia significantly strengthened the association between stress and cyberchondria (F = 107.20, p &lt; 0.01).ConclusionThe study will help medical practitioners to understand how stress and alexithymia can cause an increase in cyberchondria. This will help them to elaborate operational indications for prevention and psychological support.
Religious affiliation as a driver of immunization coverage: Analyses of zero-dose vaccine prevalence in 66 low- and middle-income countries
Authors: Santos Thiago M. , Cata-Preta Bianca O. , Wendt Andrea , Arroyave Luisa , Hogan Daniel R. , Mengistu Tewodaj , Barros Aluisio J. D. , Victora Cesar G. 
Published: October 2022

BackgroundThe literature on the association between religion and immunization coverage is scant, mostly consisting of single-country studies. Analyses in low and middle-income countries (LMICs) to assess whether the proportions of zero-dose children vary according to religion remains necessary to better understand non-socioeconomic immunization barriers and to inform interventions that target zero-dose children.MethodsWe included 66 LMICs with standardized national surveys carried out since 2010, with information on religion and vaccination. The proportion of children who failed to receive any doses of a diphtheria-pertussis-tetanus (DPT) containing vaccine – a proxy for no access to routine vaccination or “zero-dose” status – was the outcome. Differences among religious groups were assessed using a test for heterogeneity. Additional analyses were performed controlling for the fixed effect of country, household wealth, maternal education, and urban-rural residence to assess associations between religion and immunization.FindingsIn 27 countries there was significant heterogeneity in no-DPT prevalence according to religion. Pooled analyses adjusted for wealth, maternal education, and area of residence showed that Muslim children had 76% higher no-DPT prevalence than Christian children. Children from the majority religion in each country tended to have lower no-DPT prevalence than the rest of the population except in Muslim-majority countries.InterpretationAnalyses of gaps in coverage according to religion are relevant to renewing efforts to reach groups that are being left behind, with an important role in the reduction of zero-dose children.
Prognostic nutrition index predicts short-term surgical complications in patients with rectal cancer after laparoscopic surgery
Authors: Xu Fengming , Meng Cong , Yang Zhengyang , Li Haoze , Gao Jiale , Sun Liting , Zhang Xiao , Wei Qi , Wu Guocong , Yao Hongwei , Zhang Zhongtao 
Published: October 2022

PurposeSurgical complications following laparoscopic rectal cancer surgery remain a major clinical problem. The prognostic nutritional index (PNI) is reportedly associated with postoperative outcomes. We aimed to evaluate the correlation between PNI and short-term surgical complications in patients with rectal cancer after laparoscopic surgery.MethodsThe prospective clinical data of 225 patients with rectal cancer receiving laparoscopic surgery between January 2021 and April 2022 were retrospectively analyzed. The cut-off values and diagnostic accuracy of PNI preoperatively and on postoperative day (POD) 1 were determined using receiver operating characteristic (ROC) curves. Univariate and multivariate analyses were performed to identify clinical characteristics and risk factors for surgical complications.ResultsIn total, 81 (36.0%) patients developed surgical complications. The optimal cut-off value for preoperative PNI was 40.15, and that for PNI on POD 1 was 35.28. The DeLong test found no statistically between–group difference in the area under the ROC curve (P = 0.598). Multivariate analysis identified that a preoperative PNI ≤40.15 [odds ratio (OR): 2.856, 95% confidence interval (CI): 1.287–6.341, P = 0.010] and PNI on POD 1 ≤35.28 (OR: 2.773, 95% CI: 1.533–5.016, P = 0.001) were independent risk factors for surgical complications. Patients with a preoperative PNI ≤40.15 or PNI on POD 1 ≤35.28 were more likely to have surgical complications after laparoscopic surgery for rectal cancer (61.1% vs. 31.2%, P = 0.001; 53.0% vs. 28.9%, P = 0.001).ConclusionPreoperative and POD 1 PNI were independent predictors of short-term surgical complications after laparoscopic surgery for rectal cancer.
Primary closure combined with C-tube drainage through cystic duct after laparoscopic common bile duct exploration is safe and feasible for patients
Authors: Sui Xin , Sui Zhenghui , Gu Xingwei , Ding Mingjin , Miao Ganggang 
Published: October 2022

ObjectiveBiliary duct management is of great significance after laparoscopic cholecystectomy (LC) combined with laparoscopic common bile duct exploration (LCBDE) in the treatment of cholecystolithiasis accompanied with common bile duct (CBD) stones. This study is to evaluate the safety and effectiveness of primary closure with C-tube drainage through cystic duct after LC + LCBDE.MethodsThrough a retrospective study, 290 patients who underwent LC + LCBDE in our hospital from January 2019 to April 2022 were enrolled and divided into 2 groups. 143 patients underwent primary closure with C-tube drainage through cystic duct (C-tube group) and the other 147 patients underwent traditional T-tube drainage (T-tube group). Personal information, perioperative examinations, surgical results, and follow-up results were collected and analyzed.ResultsThere were no significant differences in the average age, gender, the mean of CBD diameters and the rate of comorbidities (acute cholecystitis, obstructive jaundice, acute pancreatitis and acute cholangitis) between the two groups (P &gt; 0.05). Hospital stay, postoperative hospital stay were significantly shorter in the C-tube group than T-tube group (P &lt; 0.05). In addition, the average time of placing and removal the drainage tubes was significantly less than those of the T-tube group (P &lt; 0.05). This study also showed significant differences in the incidence of postoperative abdominal infection and soft tissue infection in the two groups (P &lt; 0.05). There were no significant differences in the incidence of postoperative complications including cholangitis, bile duct stenosis, mortality in two groups. There were also no significant differences between the two groups of the recurrence of CBD stones, reoperation and readmition in 30 days during the median follow-up of 6 months.ConclusionsCompared with T tube drainage, patients with C-tube drainage after LC + LCBDE with primary closure of cystic duct recovered faster and had fewer complications. C-tube drainage is a safe and feasible treatment option for patients with cholecystolithiasis and choledocholithiasis.
Satisfação e percepção de médicos atuantes na atenção primária à saúde sobre a implementação de educação continuada em endocrinologia
Authors: Reis Baruqui Rafael , Vargas Ferreira Lize , Feres Gomes Chamon Assú Gabriel , Rocha Firmo Camila , Guedes Ezequiel Andrade Danielle , De Souza Tolêdo Leal Christianne 
Published: October 2022

Introdução: A atenção primária à saúde (APS) é responsável pelo cuidado integral e longitudinal do usuário dentro do contexto de sua família e comunidade, além de organizar o fluxo de pacientes pelo sistema de saúde, logo há importância de constante atualização científica da equipe de saúde. Ademais, o acompanhamento de indivíduos com doenças endocrinológicas é demanda frequente nas unidades básicas de saúde. Objetivo: Avaliar a satisfação e a percepção dos profissionais com essa estratégia educacional. Material e Métodos: Foi realizado projeto de educação continuada virtual em endocrinologia durante 6 meses de encontros semanais com 128 médicos da APS. Após esse período, foi realizado um questionário semi-aberto on-line. A análise quantitativa foi realizada por meio da distribuição das frequências dos dados tabulados e os dados qualitativos foram analisados por meio de análise de conteúdo temática proposta por Bardin. Resultados: Foram obtidas 44 respostas do questionário on-line pelos médicos da APS. O formato de aula que resultou em melhor aproveitamento foi o modelo de "apresentação e discussão”. Por outro lado, o formato de “só apresentação de slides” possuiu a pior avaliação. Na avaliação dos diversos temas apresentados, observou-se maior repercussão positiva à prática clínica temas como insulinoterapia e tratamento medicamentoso no diabetes mellitus 2, doença renal crônica e estadiamento do risco cardiovascular. Alguns profissionais relataram que a implementação da educação continuada possibilitou aos médicos da APS experiências de maior aprendizado, desde aspectos fisiopatológicos até abordagens direcionadas para problemas reais da prática clínica. Outros relataram desafios quanto ao horário dos encontros e à forma de apresentação da aula. Obteve-se doze respostas discursivas: sete (58,3%) referiram satisfação e benefícios, duas (16,7%) críticas e três (25%) sugestões referentes ao projeto. Conclusão: Os resultados mostraram que a educação continuada virtual em endocrinologia se apresentou como uma ferramenta adequada e satisfatória para os médicos da APS.
Análise da mortalidade infantil no leste de Minas Gerais, 2008-2019
Authors: Reis Silva Fillipe , Nilson Aguiar e Moura Davi , Figueiredo Gonçalves Mateus , Batista Gusmão Rômulo , Dias de Freitas Eulilian , De Oliveira Simões Milena , Alexandra Alves Waneska 
Published: October 2022

Introdução: A taxa de mortalidade infantil (TMI) é a frequência de óbitos de crianças menores de um ano de idade a cada mil crianças nascidas vivas. Objetivo: Caracterizar a incidência dos óbitos e o desempenho da TMI em relação às principais variáveis sociodemográficas e clínicas da criança e da mãe, na Macrorregião Leste de Minas Gerais, de 2008 a 2019. Materiais e Métodos: Foram utilizados dados secundários de domínios público dos Sistemas de Informação de Mortalidade e de Nascidos Vivos da Secretaria Estadual de Saúde de Minas Gerais na construção de um estudo ecológico de series temporais e abordagem descritiva observacional de caráter transversal. Resultados: Foram registrados 1.517 óbitos e TMI acumulada de 14,3/1000 nascidos vivos (NV). Na análise ano a ano não foi possível observar um padrão temporal conforme observado no âmbito nacional e estadual, sendo que a curva da evolução temporal da TMI mostrou-se anárquica. O componente neonatal precoce registrou as maiores taxas. Na análise dos dados maternos, destacou-se por estarem atreladas às taxas mais elevadas, a baixa escolaridade (123,5 e 21,5/1000 NV), a idade reprodutiva em extremos (27,5 e 52,6/1000 NV) e o parto vaginal (15,7/1000 NV). Já em relação à criança, o sexo masculino (15,6/1000 NV), a raça/cor branca (20,3/1000 NV) e nascimentos ocorridos em domicílio (328,24/1000 NV) apresentaram maior TMI. Observou-se um alto percentual de mortes evitáveis (68%) destacando aquelas que são evitáveis por adequada atenção a mulher na gestação como a mais pronunciada. Conclusões: Com base nesses achados, nota-se a necessidade da gestão integrada nas redes de atenção à saúde materno-infantil ampliando assim a capacidade dos municípios de assistir com qualidade a gestação, o parto e o nascimento, a fim de atuar na redução da mortalidade infantil.
estudo de caso dos alunos com altas habilidades/superdotação na perspectiva da inclusão social e da interdisciplinaridade no contexto da educação básica em Mato Verde – MG
Authors: Barbosa Verônica Cruz Silveira , Silva Ana Cláudia Soares da , Silva Jaete Pinto da 
Published: October 2022

Os alunos com déficits de aprendizagens e superdotação devem estar inseridos em salas regulares e com professores de apoio, mediante as normas do Ministério da Educação e Cultura (MEC). Para tanto, o objetivo do presente estudo é conhecer a realidade dos alunos no Atendimento Educacional Especializado (AEE) de Altas Habilidades/ Superdotagem (AH/SD) na Escola Estadual Professor José Américo Barbosa localizada em Mato Verde-MG. O AEE na escola supracitada é caracterizado pela necessidade de conhecer e entender as relações de ensino e aprendizagem estabelecidas neste atendimento devido à grande demanda. Nesse contexto, a interdisciplinaridade configura-se pela realidade de articulação entre os educadores do ensino regular e o professor de apoio juntamente com os educandos. Portanto, aproximar as áreas do saber e promover uma nova forma de pensar e articular a interdisciplinaridade, portanto, este estudo contribui para a produção de conhecimento científico, social e educacional.
Simulasi Morfodinamika Longsor Kalisari, Kabupaten Magelang Berdasarkan Data LiDAR dan Model Numerik
Authors: Samodra Guruh 
Published: October 2022

ABSTRAK Simulasi morfodinamika longsor dapat digunakan untuk memprediksi proses dan hasil proses geomorfologi di masa mendatang. Tujuan penelitian ini adalah untuk memetakan topografi Longsor Kalisari secara rinci dengan menggunakan UAV LiDAR dan memodelkan secara spasial morfodinamika Longsor Kalisari di masa mendatang khusunya jarak luncur, area yang mungkin terpapar, kecepatan, dan ketebalan material longsoran. Metode yang digunakan meliputi pemetaan topografi, estimasi volume material yang akan longsor (initial source), penentuan reologi, dan pemodelan spasial morfodinamika longsor. Model elevasi digital (DEM) yang terdiri atas model permukaan digital (DSM) dan model medan digital (DTM)dihasilkan dari fotogrametri Unmanned Aerial Vehicle (UAV) foto udara dan LiDAR. Penentuan volume longsor awal berdasarkan data geolistrik dan model medan digital. Reologi material longsor ditentukan berdasarkan uji laboratorium sampel tanah. Pemodelan spasial morfodinamika longsor menggunakan model numerik berbasis raster. Pemetaan topografi menggunakan UAV LiDAR sangat superior dibandingkan dengan menggunakan Structure-from-Motion (SfM) foto udara. Pemindaian dengan LiDAR dapat menghasilkan model medan dengan mengeliminasi kenampakan vegetasi. Kombinasi teknologi LiDAR dan pemodelan numerik dapat diandalkan untuk memprediksi morfodinamika Longsor Kalisari di masa mendatang. Hasil pemodelan morfodinamika dapat dikonversi menjadi peta kerawanan longsor yang dapat digunakan sebagai acuan perencanaan penggunaan lahan berbasis pengurangan risiko bencana longsor pada skala rinci.Kata kunci: geomorfologi, morfodinamika longsor, LiDAR, model numerik ABSTRACT Landslide morphodynamic analysis can be employed to predict geomorphological processes and landforms in the future. The objectives of the research are to map detailed topographical features of Kalisari Landslide using UAV LiDAR and to model its morphodynamic spatially including runout distance, inundated area, velocity and height of the material. Digital Elevation Model (DEM) consisting of Digital Surface Model (DSM) and Digital Terrain Models (DTM) were obtained from UAV photography and LiDAR. The volume of material was estimated from elecrical resistivity data and DTM. Rheology was estimated from the laboratory soil test. Landslide morphodynamics were generated from raster-based numerical model. Topographic mapping using LiDAR is more superior to that of UAV photogrammetry. LiDAR scanning can generate digital terrain model by eliminating vegetation. The combination of UAV LiDAR and numerical model can be well-implemented to predict the morphodynamic of future Kalisari Landslide. The results of the model can be directly converted to landslide susceptibility map which can be used as a reference for large scale/ detailed land use planning based on landslide disaster risk reduction. Keywords: geomorphology, landslide morphodynamic, LiDAR, numerical model