bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Situasi Masalah Kesehatan Penyakit Menular di Provinsi Kalimantan Barat
Authors: Luqman Luqman , Sudaryo Mondastri Korib , Suprayogi Antonius 
Published: March 2022

Background: Health problems in West Kalimantan are dominated by infectious diseases based on health data showing that the list of the top 10 diseases is dominated by infectious diseases, the CFR rate is still quite high and outbreaks routinely occur due to infectious diseases. The purpose of the situation analysis is to determine priorities for infectious disease problems in West Kalimantan in 2019.Methods: This research was conducted from December 2020 to February 2021 in West Kalimantan Province. The research method used is an assessment method whose results will be presented descriptively with quantitative and qualitative approaches. Determining the priority of the problem using the PAHO-Adapted Hanlon method with assessment criteria based on the size of the problem, seriousness of the problem, intervention effectiveness, inequity and institutional factors by means of interviews with related parties within the West Kalimantan Provincial Health Office.Result: The results of the analysis of infectious disease problems in West Kalimantan Province show that the top 10 diseases are still dominated by infectious diseases such as diarrhea, TB and DHF. The CFR figure which is still quite high is contributed by TB, HIV/AIDS, diphtheria and DHF. In this study, TB was selected as a priority health problem because it obtained the highest PAHO score of 25.16. TB is still a major problem because case finding has not reached the national target of 80%, there is still transmission in the community and cases of TB in children are still quite high.Conclusion: Tuberculosis is a priority infectious disease problem in West Kalimantan. TB is the first priority problem in this study because case finding is not optimal, there is transmission in the community and there are still cases of TB in children. It is hoped that with monitoring and evaluation of training for cadres and health workers, screening of TB patients can be more massive and sensitive for providing complete TB treatment.
Hubungan Kualitas Tidur dengan Kontrol Glikemik pada Penderita Diabetes Melitus : Systematic Review
Authors: Azizah Ulfa Nur , Wurjanto Moh Arie , Kusariana Nissa , Susanto Henry Setyawan 
Published: March 2022

Background: People with Diabetes Mellitus often wake up at night to urinate, thereby reducing the quality of sleep. Sleep quality is related to HbA1c levels. There are many studies regarding the relationship between sleep quality and glycemic control with the results that there is a relationship or no relationship.Methods: This study uses the Systematic Review method with PRISMA guidelines without meta-analysis. Databases used: ScienceDirect, PubMed, Scopus and Portal Garuda. The selected articles were critically assessed with Joanna Briggs Institute questionnaire.Result: There were 17 articles deserved to be analyzed. Many studies state that there is a relationship between global PSQI scores and sleep duration with HbA1c. PSQI is a predictor of HbA1c. The relationship between sleep duration and HbA1c is U-shaped.Conclusion : This study shows that sleep quality is related to glycemic control.
Faktor-Faktor yang Berhubungan dengan Kejadian Coronavirus Disease 2019 (COVID-19) di Provinsi Jawa Tengah
Authors: Damayanti Rahmita , Sutiningsih Dwi , Kusariana Nissa , Hestiningsih Retno 
Published: March 2022

Background: Coronavirus Disease 2019 (COVID-19) is a global pandemic disease which attacked respiratory organ and caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Central Java is the third-ranked province with the most positive COVID-19 cases in Indonesia and is still experiencing additional cases until December 2021. Central Java has also been the province with the highest number of COVID-19 red zones in Indonesia. Factors related to COVID-19 have to be known so the efforts to prevent COVID-19 can be carried out effectively and the risks of infection can be decreased. This study aims to analyze the factors related to COVID-19 infections of Central Java population.Methods: This research is an analytical study with a cross sectional approach. The research method is quantitative. The research samples were 200 citizens of Central Java Province. The sampling technique was proportional to size sampling. This study used a questionnaire for data collection.Result: The results of the research show that the factors related to COVID-19 infections are sex (p-value = 0.007), smoking status (p-value = 0.017), comorbidity status (p-value = 0.000), alcohol consumption behavior (p-value = 0.000), and preventive practice of COVID-19 (p-value = 0.001).Conclusion : It can be concluded that sex, smoking status, comorbidity status, alcohol consumption behavior, and preventive practice of COVID-19 are factors related to COVID-19 infections.
Pemanfaatan Arang Aktif Tempurung Kelapa (Cocos nucifera) untuk Mengikat Kromium (Cr) (Study Pada Limbah Cair Batik)
Authors: A`yunina Ulva , Moelyaningrum Anita Dewi , Ellyke Ellyke 
Published: February 2022

Latar Belakang: Logam berat kromium (Cr) dapat menurunkan kualitas lingkungan yang berdampak pada kesehatan manusia. Sumber Cr sering berasal dari proses pewarnaan industri batik yang keluar melalui lingkungan. Limbah tempurung kelapa dapat dijadikan arang aktif yang berpotensi mengikat cemaran. Penelitian ini bertujuan untuk menganalisis penurunan kromium pada air dengan pemanfaatan limbah arang aktif tempurung kelapa.Metode: Sampel adalah air yang mengandung Cr dikontakkan dengan arang tempurung kelapa selama 60 menit, dimana terdiri dari kelompok kontrol (K) 0g/0,5L dan kelompok perlakuan 35g/0,5L (P1), 40g/0,5L (P2), dan 45g/0,5L(P3). Metode penelitian menggunakan true experiment dengan desain penelitian post-only control group design dan menggunakan Rancangan Acak Lengkap dengan enam kali pengulangan setiap kelompok. Data dianalisa menggunakan SPSS 20 dengan uji homogenitas Saphiro wilk dilanjutkan dengan one-way ANOVA. Kandungan kromium pada air di ukur dengan metode Atomic Absorption Spectrophometry (AAS).Hasil: Rerata kadar kromium pada kelompok kontrol (K) sebesar 0,04117 mg/L; kelompok 0,03069 mg/L (P1); 0,02061 mg/L (P2), dan 0,01090 mg/L (P3). Terdapat perbedaan yang signifikan (p<0,05) antara kelompok kontrol (K) dengan kelompok perlakuan.Simpulan: Arang aktif tempurung kelapa dapat menurunkan kadar kromium pada air. Semakin banyak arang aktif tempurung kelapa yang dikontakkan maka semakin menurun kadar kromium dalam air. ABSTRACT Title: The Utilitation of Coconut Shell Activated Charcoal (Cocos nucifera) to Binding the Chromium (Cr) In the Water (Study in Batik Wastewater). Background: Chromium (Cr) can effect the environment and effected on human health. Chromium can emit from batik industries because of colouring proceses. The coconut shell activated charcoal may binding the pollution. This aims of the study is analyze the the coconut shell activated charcoal to binding chromium levels in batik wastewater.Method: Samples consisted of the control group (K) is 0g / 0.5L, the first treatment group (T1) was 35g / 0.5L; 40g / 0.5L (T2), and 45g / 0.5L (T3) which contacted 60 minute. The method in this research is true experiment with post-only control group design and a completely randomized design with six times of repetitions. Data were analyzes with SPPS 20, analysis with saphiro wilk and one-way ANOVA. The Atomic Absorption Spectrophometry (AAS) method using to identified the chromium in the water.Result: The average chromium in control group (K) was 0.04117 mg / L, treatment 1 (P1) was 0.03069 mg / L, treatment2 (P2) was 0.02061 mg / L, and treatment3 (P3) was 0.01090 mg / L. There were sig correlation (p<0,05) between control group (K) and treatment groups. Conclution: Coconut Shell Activated Charcoal (Cocos nucifera) can binding the chromium in the water.
ANALISIS KETERSEDIAAN LOKASI PEMUKIMAN BERBASIS MITIGASI LONGSOR
Authors: Sudarto Arif , Utami Westi 
Published: March 2022

Pertumbuhan penduduk serta keterbatasan lahan untuk permukiman mengakibatkan sebagian masyarakat membangun permukiman pada lokasi rawan bencana. Penelitian ini bertujuan memetakan potensi lokasi permukiman berdasarkan peruntukan ruang serta aman dari ancaman longsor. Metode penelitian dilaksanakan melalui analisis spasial dengan melakukan overlay peta serta pemberian skoring dan pembobotan. Variabel fisik yang digunakan meliputi kemiringan tanah, drainase, erosi, penggunaan lahan, aksesibilitas jalan, aksesibilitas tempat penting dan kerawanan bencana longsor. Prioritas lokasi permukiman ditentukan berdasarkan kesesuaian secara fisik dan ketersediaan lokasi menurut rencana tata ruang wilayah (RTRW). Hasil analisis kesesuaian lokasi secara fisik untuk permukiman di Kecamatan Ngargoyoso menunjukkan terdapat 28,99% area sesuai untuk pemukiman, 38,83% sesuai bersyarat dan 32,18% tidak sesuai. Sementara berdasarkan ketersediaan lokasi untuk permukiman dan kesesuaian dengan RTRW, lokasi yang tersedia untuk permukiman dikelaskan menjadi lokasi tersedia (I) seluas 788,28 Ha dan lokasi tersedia (II) seluas 351,62 Ha. Pemetaan ketersediaan lokasi pemukiman diharapkan mampu memberikan arahan kepada masyarakat agar dapat bermukim pada wilayah aman dari bencana dan sesuai dengan RTRW.
The Pluralistic Foundations of Conceptual Veiling
Authors: Morley Julia 
Published: February 2022

Abstract
The theoretical foundations of Karthik Ramanna’s “Unreliable Accounts” are investigated, demonstrating the pluralistic approach which underlies his critique of the accountability and governance of the FASB. In particular, I highlight Ramanna’s use of multiple units of analysis and theoretical frameworks in his arguments for the existence of conceptual veiling, but I question the extent to which extent Ramanna’s account can be viewed as a generalisable causal explanation. Finally, avenues for future research are noted.
Infinitely many radial and non-radial sign-changing solutions for Schrödinger equations
Authors: Li Gui-Dong , Li Yong-Yong , Tang Chun-Lei 
Published: February 2022

Abstract
In the present paper, a class of Schrödinger equations is investigated, which can be stated as

−
Δ
u
+
V
(
x
)
u
=
f
(
u
)
,

x
∈

ℝ
N

.

- \Delta u + V(x)u = f(u),\;\;\;\;x \in {{\rm{\mathbb R}}^N}.

If the external potential V is radial and coercive, then we give the local Ambrosetti-Rabinowitz super-linear condition on the nonlinearity term f ∈ C(ℝ, ℝ) which assures the problem has not only infinitely many radial sign-changing solutions, but also infinitely many non-radial sign-changing solutions.
Plattformzentrierte Arbeitskoordination im kommerziellen und kooperativen Fahrradkurierwesen
Authors: Schreyer Jasmin , Schrape Jan-Felix 
Published: February 2022

Zusammenfassung
Dieser Aufsatz vergleicht den Einsatz digitaler Plattformen in kommerziellen und kooperativen Arbeitszusammenhängen. Auf der Basis zweier qualitativer Fallstudien zu dem automatisierten Arbeitsmanagement in der kommerziellen Gig Economy (Lieferando.de) und der kollektiven Nutzung informationstechnischer Plattformen in kooperativen Projekten (Crow Cycle Courier Collective) diskutieren wir das veränderte Zusammenspiel von technischen und sozialen Strukturierungsleistungen in der Koordination von Arbeit.
Two co-inherited hemoglobin variants revealed by capillary electrophoresis during quantification of glycated hemoglobin
Authors: Antonello Giovanni , Lo Monaco Carlo , Napoli Patrizia , Solimando Daniela , Curcio Cristina , Barberio Giuseppina , Maoggi Sauro , Ivaldi Giovanni , Nigra Marco 
Published: February 2022

Abstract

Objectives
The observation of numerous new structural defects in hemoglobin (Hb) has often been linked to the evolution and development of device technologies used for the separation and quantification of hemoglobin components. However, the increased use of preventive tests for hemoglobinopathies and separative methods to quantify glycated hemoglobin (HbA1c) also contributed to these observations, as demonstrated by the case described here. Our aim is to emphasize that different separative method can provide more useful information in patient management.

Methods
A 64-year-old diabetic woman of Moroccan descent was examined in the context of HbA1c monitoring. The test was performed using high performance liquid chromatography (HPLC) and capillary electrophoresis (CE) systems. Molecular characterization was performed by direct sequencing of the β and α globin genes.

Results
The two methods used showed the presence of an anomalous fraction identified as HbS, already observed previously, but only through CE it was possible to observe the presence of another variant and its hybrid components. Direct sequencing of β and α globin genes confirmed heterozygous HbS [β6 (A3) Glu→Val; HBB: c.20A>T] and allowed to identify a mutation on the α
2, [α114 (GH2) Pro→Leu gene; HBA2: c.344C>T] corresponding to the rare Hb Nouakchott variant.

Conclusions
The two Hb variants highlighted by the EC and the molecular characterization therefore allowed adequate advice, the correct assessment of HbA1c and metabolic status and therefore better clinical management of the patient. The availability of different instruments in the same laboratory, confirming situations of diagnostic uncertainty, represents a valuable opportunity that should be encouraged.
SIKM – a smart cryptographic key management framework
Authors: Chaeikar Saman Shojae , Ahmadi Ali , Karamizadeh Sasan , Chaeikar Nakisa Shoja 
Published: February 2022

Abstract
For a secure data transmission in symmetric cryptography, data are encrypted and decrypted using an identical key. The process of creating, distributing, storing, deploying, and finally revoking the symmetric keys is called key management. Many key management schemes are devised that each one is suitable for a specific range of applications. However, these schemes have some common drawbacks like the hardness of key generation and distribution, key storage, attacks, and traffic load. In this article, a key management framework is proposed, which is attack resistant and transforms the current customary key management workflow to enhance security and reduce weaknesses. The main features of the proposed framework are eliminating key storage, smart attack resistant feature, reducing multiple-times key distribution to just one-time interpreter distribution, and having short key intervals – minutely, hourly, and daily. Moreover, the key revocation process happens automatically and with no revocation call.
Simultaneous supersingular reductions of CM elliptic curves
Authors: Aka Menny , Luethi Manuel , Michel Philippe , Wieser Andreas 
Published: February 2022

Abstract
We study the simultaneous reductions at several supersingular primes of elliptic curves with complex multiplication.
We show – under additional congruence assumptions on the CM order – that the reductions are surjective (and even become equidistributed) on the product of supersingular loci when the discriminant of the order becomes large.
This variant of the equidistribution theorems of Duke and Cornut–Vatsal is an(other) application of the recent work of Einsiedler and Lindenstrauss on the
classification of joinings of higher-rank diagonalizable actions.
Connectedness of Kisin varieties associated to absolutely irreducible Galois representations
Authors: Chen Miaofen , Nie Sian 
Published: February 2022

AbstractWe consider the Kisin variety associated to ann-dimensional absolutely irreducible modpGalois representationρ¯{\bar{\rho}}of ap-adic fieldKtogether with a cocharacter μ. Kisin conjectured that the Kisin variety is connected in this case. We show that Kisin’s conjecture holds ifKis totally ramified withn=3{n=3}or μ is of a very particular form. As an application, we get a connectedness result for the deformation ring associated toρ¯{\bar{\rho}}of given Hodge–Tate weights. We also give counterexamples to show Kisin’s conjecture does not hold in general.
Robust numerical method for singularly perturbed differential equations with large delay
Authors: Abdulla Murad Ibrahim , Duressa Gemechis File , Debela Habtamu Garoma 
Published: February 2022

Abstract
In this paper, a singularly perturbed differential equation with a large delay is considered. The considered problem contains a large delay parameter on the reaction term. The solution of the problem exhibits the interior layer due to the delay parameter and the strong right boundary layer due to the small perturbation parameter ε. The resulting singularly perturbed problem is solved using the fitted non-polynomial spline method. The stability and parameter uniform convergence of the proposed method is proved. To validate the applicability of the scheme, two model problems of the variable coefficient are considered for numerical experimentation.
Kolaviron ameliorates chronic unpredictable mild stress-induced anxiety and depression: involvement of the HPA axis, antioxidant defense system, cholinergic, and BDNF signaling
Authors: Ishola Ismail O. , Olubodun-Obadun Taiwo G. , Bakre Oluwasayo A. , Ojo Emmanuel S. , Adeyemi Olufunmilayo O. 
Published: February 2022

Abstract

Objectives
This study sought to investigate the beneficial effect of kolaviron (KV) (a biflavonoid) isolated from Garcinia kola seed on chronic unpredictable mild stress (CUMS)-induced anxiety- and depressive-like behavior.

Methods
Male albino mice were randomly divided into six groups (n=8) as follows; Group I: vehicle-control unstressed; Group II: CUMS-control; Group III-V: CUMS + KV 1, 5 or 50 mg/kg, respectively, Group VI: KV (50 mg/kg, p.o.) unstressed mice. Animals were subjected to CUMS for 14 days, followed by estimation of depressive- and anxiety-like behavior from days 14–16. This was followed by biochemical assays for oxidative stress, hypothalamo-pituitary axis, cholinergic, and BDNF signaling.

Results
CUMS caused significant reduction in time spent in open arms of elevated plus maze test (EPM) and increase in immobility time in tail suspension test (TST) and forced swim test (FST) ameliorated by KV treatments. KV administration also attenuated CUMS-induced malondialdehyde/nitrite generation and decrease in antioxidant enzymes activities in the prefrontal cortex and hippocampus. CUMS increased serum corticosterone, acetylcholinesterase activity, and reduced BDNF level in the PFC and hippocampus were attenuated by KV administration.

Conclusions
KV prevented CUMS induced anxiety- and depression-like behavior in mice through enhancement of antioxidant defense mechanisms, neurotrophic factors, and cholinergic systems.
Evaluation of the stability of furosemide in tablet form during six-month storage in spaceflight and peculiarities of its pharmacokinetics and pharmacodynamics under conditions of anti-orthostatic hypokinesia
Authors: Polyakov Alexey V. , Svistunov Andreу A. , Kondratenko Svetlana N. , Kovachevich Irina V. , Repenkovа Lyudmila G. , Savelyevа Marina I. , Shikh Evgenia V. , Noskov Victor B. 
Published: February 2022

Abstract

Objectives
The present study investigated the stability of furosemide under space-flight conditions on board the International Space Station, as well as its pharmacokinetics and pharmacodynamics under conditions simulating exposure to some space-flight factors.

Methods
Quantitative analysis of furosemide tablets by HPLC was performed before spaceflight (background), then after six months storage under normal ground conditions (control) and under spaceflight conditions (SF). The pharmacokinetics and pharmacodynamics of furosemide were studied in six healthy volunteers after a single oral dose of 40 mg under normal conditions (background) and under anti-orthostatic hypokinesia (ANOH).

Results
Quantitative content of furosemide in tablets before SF was 40.19 ± 0.28 mg (100.47 ± 0.71%), after 6 months storage: under normal conditions (control) – 39.9 ± 0.39 mg (99.73 ± 0.98%), under SF – 39.24 ± 0.72 mg (98.11 ± 1.80%), which was within the prescribed limits. Studying basic hemodynamic parameters showed that in ANOH conditions 6 h after furosemide administration there was a statistically significant increase of the stroke volume (SV) (+36.5 Δ%), a tendency for increasing of the stroke index (SI) (+36.5 Δ%) and decreasing of the total peripheral resistance (TPR) (−21.9 Δ%) compared to baseline study.

Conclusions
It has been established that various factors of space flight (overloading, excessive vibration, microgravity, etc.) do not negatively influence the stability of furosemide in tablet form during storage for 6 months on board the International Space Station.
Datura stramonium abrogates depression- and anxiety-like disorders in mice: possible involvement of monoaminergic pathways in its antidepressant activity
Authors: Akanji Murtala A. , Elijah Oyinloye O. , Oyedolapo Alabi A. , Aderonke Aderionla A. , Opeoluwa Ogunjimi L. , Omoloye Adesina A. , Oladoja Farouk A. , Olatundun Shonde O. , Edatomolaosi Osipitan L. 
Published: February 2022

Abstract

Objectives
Ethno-botanical surveys uncovered the use of Datura stramonium in the management of mental health abnormalities. Antidepressant- and anxiolytic-like activities of hydroethanol leaf extract of D. stramonium (HLDS) in mice and its possible mechanism of action were investigated in this study.

Methods
The hole-board test (HBT), open field test (OFT), elevated plus maze test (EPMT), and social interaction test (SIT) were used to investigate the anxiolytic-like activity while forced swim test (FST) and tail suspension test (TST) were employed for the antidepressant effect. Mice were pre-treated orally with purified water (10 mL/kg), bromazepam (1 mg/kg), fluoxetine (20 mg/kg) and D. stramonium (25, 50, 100 and 200 mg/kg). One hour post-treatment, mice were subjected to the various tests.

Results
In HBT, D. stramonium increased the head dips and sectional crossings turnover. D. stramonium increased the number of square crossed and rearings/assisted rearings in OFT. DS increased the time spent in open arms of EPM. In SIT, D. stramonium increased the frequency/duration of interactions. In FST and TST, D. stramonium decreased the duration of immobility which were reversed by doxazosin (α1 adrenoceptor antagonist) and ondasentron (5-HT3 receptor antagonist).

Conclusions
HLDS has anxiolytic- and antidepressant-like activities through modulation of serotoninergic and adrenergic neurotransmissions.
DriVE-MATH: Reimagining Education
Authors: Pinto Carla M.A. , Mendonça Jorge 
Published: February 2022

Abstract
In this paper we provide a description of the project DrIVE-MATH, highlighting the main goals, intellectual outputs, outcomes, the involved partners, and activities and reports from the three-years’ project. At the end we discuss the impact of the new proposed Education models at various levels, from students, to HEIs, to stakeholders.
Impact of Financial Crisis on Economic Growth: A Stochastic Model
Authors: Tadmon Calvin , Njike Tchaptchet Eric Rostand 
Published: February 2022

Abstract
In this paper, we develop a stochastic model to analyze how financial contagion may affect economic activity.
In the deterministic case, we show that, according to specific parameter values, the economy may converge either to a stress-free equilibrium or to a stressed equilibrium: in the former situation, the level of economic growth is maximal, while in the latter, it is reduced by financial contagion.
In the stochastic case, we compute a value around which the level of economic growth oscillates.
Numerical simulations are performed to illustrate theoretical results obtained.