bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efektivitas Model Pakem Dalam Meningkatkan Konsentrasi Belajar Anak Usia Dini
Authors: Wijayanti Wahyu , Efendi Mukhlison 
Published: January 2022

Child development, especially the age from birth to entering primary education or the age of 0-8 years is the golden age in the vulnerable human life that cannot be repeated. Therefore this period is the golden age in the vulnerable human life that cannot be repeated. Therefore this period is the right time to lay the foundations for other developments. The objectives of this research are: 1) To find out, to study the planning of the PAKEM learning model in Khairiah Jimbe Islamic Kindergarten Jenangan Ponorogo, 2) Implementation of the PAKEM learning model ini increasing early childhood learning concentration. 3) Knowing and assessing the evaluation of the implementation of the PAKEM learning model in increasing early childhood learning concentration. This research use qualitative research with the type of case study research. The data collected is in the from of primary data and secondary data and data sources come from data sources derived from observations, interviews, and documentation. The data analysis technique follows the concepts put forward by miles and huberman, namely data reduction, data presentation and conclusion drawing. Specifically, it can be described as follows: 1) PAKEM lerning planning is in accordance with Permendikbud Number 146 of 2014 article 2013. 2) The implementation of the PAKEM learning model in increasing the concentration of early childhood learning has been very good, seen from the teacher actively and creatively in teaching and give assignment. 3) The evaluation of learning in increasing the concentration of early childhood learning has been adjusted to the indicators of developmental achievement and refers to the standard of assessment
Ensemble of Deep Capsule Neural Networks: An Application to Pneumonia Prediction
Authors: Bodapati Jyostna , N Rohith V , Dondeti Venkatesulu 
Published: January 2022

Abstract
Pneumonia is the primary cause of death in children under the age of 5 years. Faster and more accurate laboratory testing aids in the prescription of appropriate treatment for children suspected of having pneumonia, lowering mortality. In this work, we implement a deep neural network model to efficiently evaluate pediatric pneumonia from chest radio graph images. Our network uses a combination of convolutional and capsule layers to capture abstract details as well as low level hidden features from the the radio graphic images, allowing the model to generate more generic predictions. Furthermore, we combine several capsule networks by stacking them together and connected them with dense layers. The joint model is trained as a single model using joint loss and the weights of the capsule layers are updated using the dynamic routing algorithm. The proposed model is evaluated using benchmark pneumonia dataset\cite{kermany2018identifying}, and the outcomes of our experimental studies indicate that the capsules employed in the network enhance the learning of disease level features that are essential in diagnosing pneumonia. According to our comparison studies, the proposed model with Convolution base from InceptionV3 attached with Capsule layers at the end surpasses several existing models by achieving an accuracy of 94.84\%. The proposed model is superior in terms of various performance measures such as accuracy and recall, and is well suited to real-time pediatric pneumonia diagnosis, substituting manual chest radiography examination.
On the Spectroscopic Analyses of Polytetrafluoroethylene Coated with Nano ZnO and SiO2
Authors: Hegazy Maroof A. , Ghoneim Rasha , Ezzat Hend A. , Zahran Heba Y. , Yahia Ibrahim S. , Elhaes Hanan , Ibrahim Medhat 
Published: January 2022

Abstract
On polytetrafluoroethylene (PTFE) polymer nanocomposites coated with basically two metal oxides (MOs), SiO2 and ZnO, as well as a mixture of the two MOs, density functional theory (DFT) computations were performed. The B3LYPL/LAN2DZ model was used to evaluate PTFE polymer nano composites suggested model structures. The physical and electrical properties of PTFE modified on surface with ZnO and SiO2 coated layer by layer change Total dipole moment (TDM) and HOMO/LUMO band gap energy ∆Eto be 13.0082 Debye and 0.6889 eV, respectively. Moreover, TDM and band gap energy (∆E) improved to 10.6053 Debye and 0.2727 eV, respectively, when the nanofiller was increased to 8 atoms. In addition, the results of the Molecular Electrostatic Potential (MESP) and the Quantitative Structure Activity Relationship (QSAR) showed that PTFE coated with ZnO and SiO2 improved electrical characteristics and thermal stability. As PTFE coated with ZnO and SiO2 layer by layer, all stability characteristics, including electrical and thermal stability, were enhanced. The improved PTFE can be used as a corrosion-inhibiting layer for astronaut suits, according to the predicted results.
Effect of Non-surgical Periodontal Therapy on Levels of Inflammatory Markers in Gingival Crevicular Fluid and Serum of Patients With Breast Cancer and Periodontitis.
Authors: Dantas Felipe Torres , Silva Pedro Henrique Felix , Carrara Hélio Humberto Angotti , Reis Francisco Jose Candido dos , Frantz Fabiani Gai , Messora Michel Reis , Messora Flávia Aparecida Chaves Furlaneto , Palioto Daniela Bazan 
Published: January 2022

Abstract
Purpose: studies have demonstrated the positive impact of non-surgical periodontal therapy (NSPT) on the control of local and systemic infection/inflammation in normosystemic and systemically compromised patients, represented by the improvement of periodontal clinical parameters and reduction in the levels of inflammatory markers in the gingival crevicular fluid (GCF), saliva and serum. This study aimed to evaluate periodontal clinical parameters and inflammatory mediators in GCF and serum, before and after NSPT, in patients with periodontitis and breast cancer, before chemotherapy. Methods: seventeen women with histopathological diagnosis of invasive ductal carcinoma and periodontitis were submitted to the evaluation of clinical periodontal parameters (plaque index – PI, bleeding on probing – BOP, probing depth – PD, clinical attachment level – CAL) and submitted to scaling and root planing (SRP), at an interval of 24 hours. At the beginning of the study (baseline), before NSPT, samples of tumor microenvironment fluid (TM), GCF and peripheral blood (serum) were collected for the determination of inflammatory markers IL-1β, TNF-α, TGF-β and IL-17, using the LUMINEX methodology. Seven days after SRP, new GCF and serum samples were obtained and analyzed.Results: TGF-β levels were significantly decreased in GCF and serum (p<0.05), while IL-17 concentrations were statistically reduced in GCF (p<0.05). Conclusion: NSPT decreased local and systemic inflammatory markers and may be an important tool in the multidisciplinary approach of women with breast cancer and periodontitis before chemotherapy.
Immune Responses and Protective Immunity in Pangasius Pangasius (Hamilton, 1822) as Induced by Outer Membrane Proteins of Edwardsiella Tarda and Aluminium Hydroxide Adjuvant Complex
Authors: Adikesavalu Harresh , Abraham Thangapalam Jawahar , Joardar Siddhartha Narayan 
Published: January 2022

Abstract
Edwardsiella tarda is considered one of the important bacterial fish pathogens. The outer membrane proteins (OMPs) of E. tarda are structurally and functionally conserved, and immunogenic. This study assessed the effects of the OMPs of E. tarda CGH9 as a vaccine without aluminium hydroxide [AH] (T1) and with AH adjuvant (T2) on the respiratory burst (ROB) activity, lymphocyte proliferation of head kidney (HK) leukocytes, and serum antibody production in pangas catfish Pangasius pangasius. The ROB activity and lymphocyte proliferation of HK leukocytes increased in both vaccinated groups compared to control. Nonetheless, the T2 group showed a gradual increase in ROB activity and lymphocyte proliferation of HK leukocytes up to 3-weeks post-vaccination (wpv). The serum antibody production in the T1 group decreased initially for up to 2-wpv and increased from 3-wpv; whereas, in the T2 group, the serum-specific antibody levels were significantly high from 1-wpv compared to control. Simultaneously, the protective efficacy in terms of relative percentage survival (RPS) in the T2 group after injecting with a lethal dose of E. tarda CGH9 was high (89.00±15.56) compared to the T1 group (78.00±0.00). Furthermore, the catfish administered with a booster dose of E. tarda OMPs with or without AH adjuvant showed no additional increase in immune response or protective immunity. These results suggested that E. tarda OMPs and AH adjuvant complex has a higher potential to induce protective immunity, which may be a good choice as a vaccine to combat E. tarda infection in catfish.
Spatial Analysis of Urban Thermal Island in Northern Iran (Case Study: Rasht City)
Authors: Mohammadpourzeid Ali , Alijani Bohloul , Akbary Mehry , Zeaieanfirouzabadi Parviz 
Published: January 2022

Abstract
Land surface temperature (LST) is one of the key parameters in hydrology, meteorology, and the surface energy balance.The one-window algorithm of Kim et al. Uses Landsat satellite imagery to model the earth's surface temperature.These trends are validated using meteorological data. Two main and basic factors play a major role in the temporal and spatial trend of the thermal islands of Rasht. These two factors of climate change that have occurred in the last two decades in the region of Gilan province and the city of Rasht. The second factor that has greatly enhanced the effect of the first factor is the human factor that has greatly included other urban factors in Rasht, including urban management and proper urban planning in the province and the city of Rasht. These two factors in the temporal and spatial trend of urban thermal islands have caused thermal islands to rapidly increase the growth of the city and urban population from the urban center to the western and southwestern regions and have very negative effects on land use changes and human areas. It has caused the construction of Rasht city.
Patients´ experiences in a newly established clinic for late complications after colorectal and anal cancer treatment: a qualitative study
Authors: Oggesen Birthe Thing , Akbar Momena , Hamberg Marie Louise Sjødin , Danielsen Anne Kjaergaard , Thomsen Thordis , Rosenberg Jacob 
Published: January 2022

Abstract
Purpose
Treatment of late complications is not systematically provided in Denmark. We therefore established a clinic to treat patients´ late complications. With this study we wanted to explore patients´ experiences with treatment and care in the clinic, including their recommendations for the future organization and structure of the clinic.
Methods
We conducted a qualitative semi-structured interview study with patients who had attended our late complication clinic after treatment for colorectal or anal cancer.
Results
We included 14 patients. We found two main categories: 1: benefitting from the late complication clinic and 2: preparation and delivery of the consultations. Patients benefitted from attending the late complication clinic and some experienced complete relief from symptoms. Others did not, but they gained hope that they might be able to receive treatment in the future. Patients wished for more information about late complications, preferring that the most common symptoms were described along with patient-friendly treatment options. The patients were satisfied with telephone consultations, as they were easy to fit into a daily schedule, and patients found it easy to express themselves openly.
Conclusions
Patients were satisfied with the late complication clinic as they felt it gave them a safety net. For the future, patients recommended provision of more information about late complications and possible treatments.
Self Efficiency And Symptom Control of Cancer Patients
Authors: Kurt Seda , Sarıkaya Nihan Altan 
Published: January 2022

Abstract
Objective: This cross-sectional study was planned to evaluate the self-efficacy and symptom control of cancer patients and to determine the factors affecting them. Methods: The sample of the study consisted of 329 cancer patients who were treated in the Medical Oncology Clinic of a university hospital between April and June 2019 and accepted to participate in the study. Data were collected using the Patient Characteristics Information Form, Cancer Behavioral Inventory-Short Version (CBI-SV), and Edmonton Symptom Assessment Scale (ESAS). Percentage, mean, Mann Whitney U test, Kruskal Wallis analysis of variance were used in the analysis of the data. Results: The mean CBI-SV score of the patients was 79.10±17.55. It was determined that the highest mean score of ESAS of the patients was in the symptom of fatigue (3.53±2.81). Some symptoms were statistically lower in patients with good income, working, and non-smokers. Also it was determined that the self-efficacy levels of the patients with good income and quitting smoking were higher (p<0.05). At the same time, as the patients' self-efficacy scores increased, the severity of the symptoms they experienced decreased statistically (p<0.05). Conclusion: It was found that the patients' self-efficacy score was above the moderate level, the most intense symptom experienced by the patients was fatigue, and the severity of the symptoms decreased as the patients' self-efficacy level increased. In line with these results; the symptoms, self-efficacy perceptions and affecting factors of cancer patients should be evaluated by nurses at regular intervals, and care and consultancy services should be provided.
Evaluation of VEP Parameters in Patients Before and After Cardiopulmonary By-Pass Surgery
Authors: Güneş Alper , Konuk Serife Gulhan , Demir Helin Deniz , Kurt Semiha , Naseri Erdinç , Erkorkmaz Ünal 
Published: January 2022

Abstract
Introduction: Coronary bypass surgery is emphasized in aetiology of ischemic optic neuropathy. Our aim in this study was to investigate the pattern visual evoked potentials (PVEP) in patients before and after coronary bypass surgery.Methods: Thirty-one patients were included in the study. After a full ophthalmological evaluation, PVEP was assesed in the pre and postoperative periods. Operative times, hematological parameters, blood pressures, number of transfusions, body temperatures, anaesthetic drugs and systemic illnesses were recorded for each patient. Results: The mean age of the patients were 59±10.4 years. There was 22 men and 9 women in the study. Only 3 of them needed transfusion during the surgery. The mean duration of the surgery was 3.2±0.7 hours. None of the patients had a history of visual disturbance or postoperative ischemic optic neuropathy. The mean VEP P100 amplitude was not statistically significantly different but the mean VEP P100 latency showed statistically significant difference between the preoperative and postoperative periods. (p=0.014) This significance was more appereant in patients with systemic illnesses. (p= 0.023) There was a positive correlation between the age and VEP P100 latency. (r = 0.402, p< 0.05) Conclusions: Although surgical techniques and equipments are developing each day in the field of cardiopulmonary bypass surgery, the contributing factors such as hypothermia, anemia and diabetes still seem to affect neurophysiological functions even after a noncomplicated surgery.
Mesoscale geomorphic change on barrier estuarine regime at the tropical coast of Chandipur, India: Evidence from assessment of grain-size distribution
Authors: Saha Koushik , SINHA SUBHAJIT 
Published: January 2022

Abstract
It is crucial for policy makers and environmental managers to determine the future dynamics of coastal wetlands, especially the existence of their response, disruption, and recovery regimes. Reconstruction of meso-scale evolution in coastal ecosystems can help to adapt coastal resource management techniques to the natural scales of system activity, thereby encouraging true biodiversity. This research provides an overview of decadal (mesoscale) geomorphic transition by high-resolution grain size analysis of a sediment deposit from a barrier estuary regime on the Chandipur coast, India. Coastal marshland’s grain size distribution (GSD) has generally been analyzed using End Member Mixing Models (EMMA) and Probability Density Function (PDF) methods (e.g. log-normal, log skew-Laplace). Although these techniques do not consider the compositional nature of the records, which can undermine the outcomes of the interpretation of sedimentary deposits. The approach to reliable granulometric analysis of lithostratigraphic sequences aims at establishing direct links between fluid dynamics and subsequent shifts in the texture of sediments. In this study, GSD analysis of marsh sediment is represented by compositional data analysis (CoDa) and a multivariate statistical framework. Barrier estuary evolution, presented by time lapses of satellite maps coupled with grain size and carbon content of marsh sediment, primarily reflects the evolving hydrodynamics of the back barrier area. These findings will provide a statistically robust analysis of the depositional system in coastal marshland. Multiannual environmental variations in the back barrier configuration illustrate the importance of this applied approach with respect to bridging the basis of estuarine evolution and process information.
Practical Tracking Control Under Actuator Saturation for a Class of Flexible-Joint Robotic Manipulators Driven by DC Motors
Authors: Li Jian , Zhu Lingling 
Published: January 2022

Abstract
This paper is devoted to the practical tracking control for a class of flexible-joint robotic manipulators driven by DC motors. Different from the related literature where control constraint is neglected and the disturbances are excluded or only exist in one subsystem, actuator saturation is considered in this paper while the disturbances are present in all the three subsystems. This leads to the incapability of the traditional schemes on this topic. For this, a novel control design scheme is proposed by skillfully incorporating adaptive dynamic compensation technique, constructive methods of command filters and an auxiliary system for the actuator saturation into the backstepping framework, and in turn to design a practical tracking controller which ensures that all the states of the resulting closed-loop system are bounded and the system output practically tracks the reference signal. It is worthwhile strengthening that a more wider class of reference signals can be tracked since they are only first order continuously differentiable but twice or more in the related literature. Finally, a numerical example is provided to validate the effectiveness of the proposed theoretical results.
Research on the Promotion of New Energy Vehicles Based on Multi-Source Heterogeneous Data
Authors: Sun Bing , Ju Zhuofang 
Published: January 2022

Abstract
Under the background of green development, new energy vehicles(NEVs), as an important strategic emerging industry, play a crucial role in energy conservation and emission reduction. In the post-epidemic era, steadily promoting the promotion of NEVs will be a hot topic. Based on heterogeneous source data, combined with the Latent Dirichlet Allocation (LDA) topic model, Social Network Analysis (SNA), and econometric methods, this paper explores whether individual purchase decisions and company-level cooperative research and development will promote the promotion of new energy vehicles. The results show that whether BEV, HEV, or PHEV, users are more concerned about space dimension, power performance, and design style; Patent collaboration network analysis indicates that NEV enterprises are establishing close partnerships, which will urge the promotion of NEVs; For BEV and HEV models, new energy vehicle companies will invest more patents and R&D investment will better expedite the advancement of NEVs.
Hepatic serine and lipid metabolism drive diabetic peripheral neuropathy
Authors: Metallo Christian , Handzlik Michal , Gengatharan Jivani , Frizzi Katie , McGregor Grace , Martino Cameron , Rahman Gibraan , Gonzalez Antonio , Moreno Ana , Green Courtney , Lin Terry , Ideguchi Yoichiro , Fallon Regis , Chaix Amandine , Wallace Martina , Mali Prashant , Gantner Marin , Calcutt Nigel , Knight Robin 
Published: January 2022

Abstract
Type 2 diabetes represents a disease spectrum in which chronic metabolic dysfunction damages multiple organ systems including liver, kidneys, and peripheral nerves1,2. While onset and progression of these co-morbidities are linked with insulin resistance, hyperglycaemia and dyslipidemia3-7, aberrant amino acid metabolism also contributes to pathogenesis of diabetes and potentially its complications8-10. Serine and glycine are closely related non-essential amino acids11,12 that are consistently reduced in patients with metabolic syndrome10,13-16, but the mechanistic drivers of serine deficiency and the downstream metabolic and phenotypic consequences remain unclear. Low systemic serine, a serine-opathy, is also emerging as a hallmark of macular and peripheral nerve disorders. Specifically, serine deficiency correlates positively with impaired visual acuity and peripheral neuropathy (PN)17-19. Here we demonstrate that aberrant serine homeostasis in the liver drives serine and glycine deficiencies in genetically obese and hyperglycaemic mice. This serine-opathy can be diagnosed with a serine tolerance test that quantifies systemic serine disposal. Mimicking these metabolic alterations via dietary serine/glycine restriction together with high fat intake dramatically accelerates thermal hypoalgesia in mice and reduces epidermal sensory nerve density, which are accompanied by extensive sciatic nerve lipid remodeling. These phenotypes were subsequently normalized by myriocin, linking serine-associated PN with sphingolipid biosynthesis. These findings identify systemic serine deficiency and dyslipidemia as novel risk factors for PN that may be exploited therapeutically.