bluuebunny/crossref_metadata_2025_split huggingface dataset:
Somatic status of adolescent girls with gynecological disorders born with low and excessive weight
Authors: Tuchkina I. , Pylypenko N. , Tuchkina M. , Piontkovska O. , Romanova N. , Kachaylo I. 
Published: January 2022

In modern conditions, health problems (somatic, reproductive, mental) of adolescent girls occupy a special place in the health care system, as a reserve in reducing maternal and infant mortality, maintaining the fertility of the expectant mother.
The aim. To study the frequency and character of extragenital diseases of adolescent girls with gynecological pathology, born with low and excessive body weight.
Materials and methods. The project design is a population-based prospective cohort study. To achieve the goal and the implementation of the tasks, a prospective examination of girls and adolescent girls born with deficiency or excess body weight was carried out. The sample size was 77 people. Additionally, statistical processing was carried out using the Excell software.
Results. Thus, the study of somatic health indicates its deterioration in the groups of girls born with polar values ​​of body weight. In groups 1 and 3, infectious diseases were identified, which can serve as a starting point in the development of reproductive system disorders. In girls of group 1, mumps prevailed (20.0%), which could cause damage to the follicular apparatus, while in group 3, girls were more likely to have influenza (25.8%), the virus of which has a damaging effect not only on the structure of the ovaries, but also on endometrium.
Conclusions. Comparative analysis of the structure of somatic morbidity made it possible to identify the most significant pathology characteristic of each of the groups. Girls born with a large body weight have an increased risk of endocrine pathology. In girls born with low body weight, somatic diseases associated with manifestations of diseases of the musculoskeletal system prevail.
This dictates the need to single out girls born with polar values ​​of body weight in the risk group for the development of somatic pathology and requires complex therapeutic and prophylactic measures.
Myocardial stunning in patients with coronary artery disease before and after treatment by method of coronary artery bypass grafting (own studies)
Authors: Kundina V. , Babkina T. 
Published: January 2022

Aim of the study: Determination of quantitative radiological indicators of myocardial revascularization effectiveness in patients with coronary artery disease in the early postoperative period.
Materials and methods of research: For the implementation of the clinical objectives, 62 patients with coronary artery disease, heart failure, with preserved systolic function and systolic dysfunction were examined in the early postoperative period (up to 7 days). The patients' age ranged from 40 to 79 years, the average age of the examined was 59.6 ± 8.2 years. 35 (56%) patients had HF with LV systolic dysfunction with EF of 49% or less. 27 (44%) patients had preserved systolic function - ejection fraction greater than or equal to 50%.
Results: In the group before treatment, the average value ​​of MV was 69.4% CI 95% [65.3%; 73.5%], and after treatment the value of MV was 75.0% CI 95% (70.8%; 79.3%], p = 0.0000. Percentage of RFP inclusion in the anterior wall was 69.5% CI [66.2%; 72.8%] before treatment and significantly improved to 72.3% CI [69.1%; 75.4%] after treatment (p = 0.023). Lateral wall had a parameter value of 73.9% CI [70.7%; 77.1%] before treatment and improved perfusion up to 77.2% CI [74.3%; 80.2%] (p = 0.018). Parameter values for the intraventricular septum were 64.5% CI [60.7%; 68.3%] before treatment and 69% CI [65.2%; 72.8%] after treatment (p = 0.000034) and for the inferior wall those were 54.0% CI (49.7%; 58.3%] and 61.7% CI (57.9%); 65.6%] before and after treatment respectively (p = 0.000032).
Conclusion: The determination of quantitative radiological parameters proposed as a result of this study is extremely important for the early postoperative period (7-10 days) for determination of stunned myocardial reserve and late stage of patients` management (1-1.5 years) for determination of hibernation reserve and final assessment of CABG effectiveness.
Fast reconstruction technology of a laser beam spatial transmission characteristic curve
Authors: Liu Jianing , Meng Jin , Lyu Jiahang , Wang Shifeng 
Published: January 2022

The traditional multiposition method of the

M
2

factor measurement system is a good method, but it is relatively time consuming, so it cannot meet the requirements of the transient test of a Gaussian beam. To solve this problem, a quadriwave lateral shearing interferometer and a wavefront construction method based on a difference Zernike polynomial are analyzed. This interferometer uses a special grating to select four replicas of the wavefront, and the interferogram generated by four replicas includes difference wavefront information. Then the difference Zernike polynomial method is used to analyze quadriwave lateral shearing interferograms. The characteristic parameters are obtained after finding the optimal terms of the Zernike polynomials. As a result, the errors of F-number, beam radius, and radius of curvature are 3.7%, 3.8%, and 0.6%, respectively, which verifies this method to calculate parameters of Gaussian beam. In addition, we also find that the shear amount has influence on the reconstructed wavefront. It is showed that as the amount of shear increases from 20 pixels to 90 pixels, the peak-to-valley (P-V) values and RMS values both gradually decrease with a nonlinear relationship, which could be used to decrease the error of wavefront reconstruction further.
Chronic kidney disease biomarkers and mortality among older adults: A comparison study of survey samples in China and the United States
Authors: Miao Hui , Liu Linxin , Wang Yeli , Wang Yucheng , He Qile , Jafar Tazeen Hasan , Tang Shenglan , Zeng Yi , Ji John S. 
Published: January 2022

Objectives
Among older adults in China and the US, we aimed to compare the biomarkers of chronic-kidney-diseases (CKD), factors associated with CKD, and the correlation between CKD and mortality.

Setting
China and the US.

Study design
Cross-sectional and prospective cohorts.

Participants
We included 2019 participants aged 65 and above from the Chinese Longitudinal Healthy Longevity Study (CLHLS) in 2012, and 2177 from US National Health and Nutrition Examination Survey (NHANES) in 2011–2014.

Outcomes
Urinary albumin, urinary creatinine, albumin creatinine ratio (ACR), serum creatinine, blood urea nitrogen, plasma albumin, uric acid, and estimated glomerular filtration rate (eGFR). CKD (ACR ≥ 30 mg/g or eGFR< 60 ml/min/1.73m2) and mortality.

Analytical approach
Logistic regression and Cox proportional hazard models. Covariates included age, sex, race, education, income, marital status, health condition, smoking and drinking status, physical activity and body mass index.

Results
Chinese participants had lower levels of urinary albumin, ACR, and uric acid than the US (mean: 25.0 vs 76.4 mg/L, 41.7 vs 85.0 mg/g, 292.9 vs 341.3 μmol/L). In the fully-adjusted model, CKD was associated with the risk of mortality only in the US group (hazard ratio [HR], 95% CI: 2.179, 1.561–3.041 in NHANES, 1.091, 0.940–1.266 in CLHLS). Compared to eGFR≥90, eGFR ranged 30–44 ml/min/1.73m2 was only associated with mortality in the US population (HR, 95% CI: 2.249, 1.141–4.430), but not in the Chinese population (HR, 95% CI: 1.408, 0.884–2.241).

Conclusions
The elderly participants in the US sample had worse CKD-related biomarker levels than in China sample, and the association between CKD and mortality was also stronger among the US older adults. This may be due to the biological differences, or co-morbid conditions.
Effects of SGLT2 inhibitors on cardiovascular outcomes in patients with stage 3/4 CKD: A meta-analysis
Authors: Li Ning , Zhou Guowei , Zheng Yawei , Lv Dan , Zhu Xiangjun , Wei Ping , Zheng Min , Liu Shijia , Zhou Enchao , Sun Wei , Zhang Lu 
Published: January 2022

Introduction
After stage 3 CKD, the risk of adverse cardiovascular events increased significantly. Therefore, we performed a meta-analysis to investigate the cardiovascular protective effect of SGLT2 inhibitors in patients with stage 3/4 CKD with different baseline kidney function or underlying diseases.

Method
To identify eligible trials, we systematically searched the Embase, PubMed, Web of Science, and Cochrane library databases from inception to April 15, 2021. The primary cardiovascular outcome was defined as a combination of cardiovascular mortality and hospitalization due to heart failure. Baseline kidney functions (stage 3a CKD: eGFR45-59mL/min per 1.73m2, stage 3b CKD: eGFR30-44mL/min per 1.73m2, stage 4 CKD: eGFR<30mL/min per 1.73m2) and underlying diseases (Type 2 diabetes, heart failure (Preserved ejection fraction or reduced ejection fraction), atherosclerotic cardiovascular disease) were used to stratify efficacy and safety outcomes. The results were subjected to a sensitivity analysis to ensure that they were reliable.

Results
In the present study, a total of eleven trials were included that involved a total of 27,823 patients with stage 3/4 CKD. The treatment and control groups contained 14,451 and 13,372 patients, respectively. In individuals with stage 3/4 CKD, SGLT2 inhibitors reduced the risk of primary cardiovascular outcomes by 26% (HR 0.74, [95% CI 0.69–0.80], I2 = 0.00%), by 30% in patients with stage 3a CKD (HR 0.70, [95% CI 0.59–0.84], I2 = 18.70%), by 23% in patients with stage 3b CKD (HR 0.77, [95% CI 0.66–0.90], I2 = 2.12%), and by 29% in patients with stage 4 CKD (HR 0.71, [95% CI 0.53–0.96], I2 = 0.00%). The risk of primary outcomes was reduced by 29% (HR 0.71, [95% CI 0.63–0.80], I2 = 0.00%) in patients with type 2 diabetes, by 28% (HR 0.72, [95% CI 0.56–0.93], I2 = 37.23%) in patients with heart failure with preserved ejection fraction, by 21% (HR 0.79, [95% CI 0.70–0.89], I2 = 0.00%) in patients with heart failure with reduced ejection fraction, and by 25% (HR 0.75, [95% CI 0.64–0.88], I2 = 0.00%) in patients with atherosclerotic cardiovascular disease.

Conclusions
For stage 3/4 CKD, SGLT2 inhibitors significantly decreased the risk of primary cardiovascular outcomes, and these benefits were consistent throughout the spectrum of different kidney functions, even in stage 4 CKD. There was no evidence of increased adverse outcomes across different baseline clinical complications, such as type 2 diabetes, heart failure, or atherosclerotic cardiovascular disease.
Upper extremity deep vein thrombosis in COVID-19: Incidence and correlated risk factors in a cohort of non-ICU patients
Authors: Mumoli Nicola , Dentali Francesco , Conte Giulia , Colombo Alessandra , Capra Riccardo , Porta Cesare , Rotiroti Giuseppe , Zuretti Francesca , Cei Marco , Tangianu Flavio , Evangelista Isabella , Vitale Josè , Mazzone Antonino , Giarretta Igor 
Published: January 2022

Background
Venous thromboembolism is a frequent complication of COVID-19 infection. Less than 50% of pulmonary embolism (PE) is associated with the evidence of deep venous thrombosis (DVT) of the lower extremities. DVT may also occur in the venous system of the upper limbs especially if provoking conditions are present such as continuous positive airway pressure (CPAP). The aim of this study was to evaluate the incidence of UEDVT in patients affected by moderate-severe COVID-19 infection and to identify potential associated risk factors for its occurrence.

Methods
We performed a retrospective analysis of all patients affected by moderate-severe COVID-19 infection admitted to our unit. In accordance with the local protocol, all patients had undergone a systematic screening for the diagnosis of UEDVT, by vein compression ultrasonography (CUS). All the patients were receiving pharmacological thromboprophylaxis according to international guidelines recommendations. Univariate and multivariate analyses were used to identify risk factors associated with UEDVT.

Results
257 patients were included in the study, 28 patients were affected by UEDVT with an incidence of 10.9% (95% CI, 7.1–14.7). At univariate analysis UEDVT appeared to be significantly associated (p< 0.05) with pneumonia, ARDS, PaO2/FiO2, D-dimer value higher than the age adjusted cut off value and need for CPAP ventilation. Multivariate analysis showed a significant association between UEDVT and the need for CPAP ventilation (OR 5.95; 95% IC 1.33–26.58). Increased mortality was found in patients affected by UEDVT compared to those who were not (OR 3.71; 95% CI, 1.41–9.78).

Conclusions
UEDVT can occur in COVID-19 patients despite adequate prophylaxis especially in patients undergoing helmet CPAP ventilation. Further studies are needed to identify the correct strategy to prevent DVT in these patients.
Protecting brains and saving futures guidelines: A prospective, multicenter, and observational study on the use of telemedicine for neonatal neurocritical care in Brazil
Authors: Variane Gabriel Fernando Todeschi , Magalhães Maurício , Pietrobom Rafaela Fabri Rodrigues , Netto Alexandre , Rodrigues Daniela Pereira , Gasperini Renato , Sant’Anna Guilherme Mendes 
Published: January 2022

Background
Management of high-risk newborns should involve the use of standardized protocols and training, continuous and specialized brain monitoring with electroencephalography (EEG), amplitude integrated EEG, Near Infrared Spectroscopy, and neuroimaging. Brazil is a large country with disparities in health care assessment and some neonatal intensive care units (NICUs) are not well structured with trained personnel able to provide adequate neurocritical care. To reduce this existing gap, an advanced telemedicine model of neurocritical care called Protecting Brains and Saving Futures (PBSF) Guidelines was developed and implemented in a group of Brazilian NICUs.

Methods
A prospective, multicenter, and observational study will be conducted in all 20 Brazilian NICUs using the PBSF Guidelines as standard-of-care. All infants treated accordingly to the guidelines during Dec 2021 to Nov 2024 will be eligible. Ethical approval was obtained from participating centers. The primary objective is to describe adherence to the PBSF Guidelines and clinical outcomes, by center and over a 3-year period. Adherence will be measured by quantification of neuromonitoring, neuroimaging exams, sub-specialties consultation, and clinical case discussions and videoconference meetings. Clinical outcomes of interest are detection of seizures during hospitalization, use of anticonvulsants, inotropes, and fluid resuscitation, death before hospital discharge, length of hospital stay, and referral of patients to specialized follow-up.

Discussion
The study will provide evaluation of PBSF Guidelines adherence and its impact on clinical outcomes. Thus, data from this large prospective, multicenter, and observational study will help determine whether neonatal neurocritical care via telemedicine can be effective. Ultimately, it may offer the necessary framework for larger scale implementation and development of research projects using remote neuromonitoring.

Trial registration
NCT03786497, Registered 26 December 2018, https://www.clinicaltrials.gov/ct2/show/NCT03786497?term=protecting+brains+and+saving+futures&draw=2&rank=1.
The International Brigades: Fascism, Freedom and the Spanish Civil War, Giles Tremlett (2020)
Authors: Pinheiro Teresa 
Published: January 2022

Review of: The International Brigades: Fascism, Freedom and the Spanish Civil War, Giles Tremlett (2020)
London: Bloomsbury, 720 pp.,
ISBN 978-1-40885-398-6, h/bk, £30.00
ISBN 978-1-52664-454-1, e-book, £11.99
Narrativas precarias: Crisis y subjetividad en la cultura española actual, Christian Claesson (ed.) (2019)
Authors: Usoz de la Fuente Maite 
Published: January 2022

Review of: Narrativas precarias: Crisis y subjetividad en la cultura española actual, Christian Claesson (ed.) (2019)
Xixón: Hoja de Lata Editorial, 348 pp.,
ISBN 978-8-41653-745-7, p/bk, €18.90
Limited Access to Integral Care: Digital Therapeutics Show Promise of Scalable Solutions to Behavioral Interventions
Authors: Riehl Megan E. 
Published: January 2022

Abstract
Functional gastrointestinal disorders, or disorders of gut-brain interaction, present significant biological, psychological, and social burdens to the individual and society at large. Emerging research shows that because of the multifactorial nature of these conditions, multidisciplinary treatment is typically needed. Traditional medical approaches now benefit from the addition of nutrition therapy and psychogastroenterology, or the use of evidence-based psychological treatments tailored to gastrointestinal conditions. Currently, there are significant barriers to receiving psychogastroenterology services and it is likely that digital therapeutics have an important place in improving treatment access and outcomes for a select group of patients.
The Effectiveness of Using Big Book Media on Early Reading Skills in 5-6 Years Old
Authors: Oktaviana Winda , Warmansyah Jhoni , Trimelia Utami Winda 
Published: January 2022

Purpose – This study aims to determine the effectiveness of using Big Book media on early reading skills in children aged 5-6 years old.Design/methods/approach – This study used a quantitative approach which was carried out in an experimental method with a pre-post-test design. The sampling technique uses a simple random technique with 30 children. Data collection technique is by means of tests. The analysis technique for testing the hypothesis uses the difference test (t-test).Findings – The results showed that children in the experimental group who used Big Book media had a higher average score when compared to children in the control group who used magazine media. Based on the t-test calculation, findings indicate that there was a significant difference between the two groups. Thus, it can be concluded that the Big Book media is effective on early reading skills in children aged 5-6 years old.Research implications/limitations – This study was limited to one location, Mutiara Al-Madani Kindergarten, Jambi Indonesia, and with a small sample size, so the generalizability of the findings was also limited. It is necessary for future researchers to conduct studies with a wider scope and a more diverse population.Practical implications – The use of Big Book media can be an alternative learning media that can attract children's interests and can actively involve children in gaining rich literacy experiences in improving early reading skills.Originality/value – This study contributes to understanding of teacher's reference material in using learning media for early reading skills in children aged 5-6 years old.
Paper type Research paper
Exploring Children's Science and Mathematics Ability with Leaf Diary: A Case Study
Authors: Yulia Resti , Mahyuddin Nenny , Nurhafizah Nurhafizah , Sulong Komareeyah 
Published: January 2022

Purpose – This study aims to explore Leaf diary activity to develop the Science and Mathematics ability of children aged 6 years.Design/methods/approach – The method used is a case study. The unit of analysis is based on predetermined criteria, using the purposive sampling technique. Research informants are mentors and children involved in leaf diary activity in Solok, Indonesia. The data collection process used participant observation, documentation, and in-depth interviews. Data analysis used structural analysis techniques.Findings – The results showed that leaf diary activity could develop: (1) children's ability to classify leaves based on their shape; (2) the ability to compare leaf size based on length, as well as large or small size.Research implications/limitations – All research informants were from Solok District, Indonesia, which may limit the generalizability of the findings.Practical implications – This case study contributes to the implementation of Leaf diary as an alternative activity that teachers or parents can do to develop children's science and mathematics ability.Originality/value – Leaf diary activity can help children explore the natural environment so that basic science and math abilities and concepts in this activity are carried out well.
Paper type Case study
IMPLEMENTASI KEADILAN GENDER DI PONDOK PESANTREN SABILURROSYAD KOTA MALANG
Authors: Sanah Bella Fadhilatus , Nafisah Ika Wildah , Mukmina Maulidina Zahrah , Cholid Satria Adli , Prayoga Taufan Adi 
Published: January 2022

Gender equality still becomes a sensitive issue in Islamic educational institutions, especially in pesantren, a traditional Islamic educational institution. There is a strong assumption that in the socio-religious tradition of pesantren, women's subordination still practices widely. However, some pesatren take serious attention to overcome this issue through their daily activities within pesantren. One of which is Pesantren Sabilurrosyad in Malang, East Java. This article aims to elaborate on the realization of gender justice in the pesantren. This research uses a qualitative approach through observation and in-depth interviews with the board members of pesantren, as well as its male and female students. The results showed that the Pesantren Sabilurrosyad had implemented the values of gender justice in their socio-religious activities. The implementation forms include providing opportunities for female students to become head of student association; female students are given freedom to recite the Koran directly to the kyai; and female teachers (ustadzah) are given the opportunity to share in one forum with male students.Kesetaraan gender masih menjadi isu sensitive di lembaga pendidikan Islam, khususnya di pondok pesantren. Terdapat anggapan bahwa dalam tradisi sosial-keagamaan di pesantren subordinasi perempuan masih terjadi. Hal ini menjadi perhatian bagi beberapa pesantren yang ingin menjadikan isu ini sebagai bagian dari aktivitas pesantren, salah satunya adalah Pondok Pesantren Sabilurrosyad di Malang. Artikel ini bertujuan untuk mengelaborasi perwujudan keadilan gender di pondok tersebut. Penelitian ini menggunakan pendekatan kualitatif melalui observasi dan wawancara mendalam terhadap para pengurus ponpes dan santri putra dan santri putri. Hasil penelitian menunjukkan bahwa pondok pesantren Sabilurrosyad telah mengimplementasikan nilai-nilai keadilan gender dalam tradisi sosial-keagamaan pesantren. Wujud implementasi tersebut diantaranya adalah memberikan kesempatan kepada santri putri untuk menjadi ketua pondok, santri putri diberikan kebebasan untuk mengaji langsung kepada kyai, serta pengajar putri (ustadzah) diberikan peluang untuk bersama 1 (satu) forum dengan santri putra.