bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indications, Clinical Impact, and Complications of Critical Care Transesophageal Echocardiography: A Scoping Review
Authors: Prager Ross , Bowdridge Joshua , Pratte Michael , Cheng Jason , McInnes Matthew DF , Arntfield Robert 
Published: July 2022

Background Critical care transesophageal echocardiography (ccTEE) is an increasingly popular tool used by intensivists to characterize and manage hemodynamics at the bedside. Its usage appears to be driven by expanded diagnostic scope as well as the limitations of transthoracic echocardiography (TTE) – lack of acoustic windows, patient positioning, and competing clinical interests (eg, the need to perform chest compressions). The objectives of this scoping review were to determine the indications, clinical impact, and complications of ccTEE. Methods MEDLINE, EMBASE, Cochrane, and six major conferences were searched without a time or language restriction on March 31st, 2021. Studies were included if they assessed TEE performed for adult critically ill patients by intensivists, emergency physicians, or anesthesiologists. Intraoperative or post-cardiac surgical TEE studies were excluded. Study demographics, indication for TEE, main results, and complications were extracted in duplicate. Results Of the 4403 abstracts screened, 289 studies underwent full-text review, with 108 studies (6739 patients) included. Most studies were retrospective (66%), performed in academic centers (84%), in the intensive care unit (73%), and were observational (55%). The most common indications for ccTEE were hemodynamic instability, trauma, cardiac arrest, respiratory failure, and procedural guidance. Across multiple indications, ccTEE was reported to change the diagnosis in 52% to 78% of patients and change management in 32% to79% patients. During cardiac arrest, ccTEE identified the cause of arrest in 25% to 35% of cases. Complications of ccTEE included two cases of significant gastrointestinal bleeding requiring intervention, but no other major complications (death or esophageal perforation) reported. Conclusions The use of ccTEE has been described for the diagnosis and management of a broad range of clinical problems. Overall, ccTEE was commonly reported to offer additional diagnostic yield beyond TTE with a low observed complication rate. Additional high quality ccTEE studies will permit stronger conclusions and a more precise understanding of the trends observed in this scoping review.
Sexual Orientation and Gender Identity-Related State-Level Policies and Perceived Health Among Lesbian, Gay, Bisexual, and Transgender (LGBT) Older Adults in the United States
Authors: Nelson Christi L. , Wardecker Britney M. , Andel Ross 
Published: July 2022

Objectives We examined the associations between state-level policies and the health of lesbian, gay, bisexual, and transgender (LGBT) older adults. Methods: Using data from the 2018–2020 Behavioral Risk Factor Surveillance System surveys, we assessed physical and mental health by the tally of points for enacted LGBT-related policies (Low= <0–49.9% of possible points, High= 50–100% of possible points) in 10,032 sexual minority (i.e., lesbian, gay, and bisexual) and 1,072 transgender (non-sexual minority) adults aged 50 and older from 41 states. Results: Sexual minority adults in low tally states had greater odds of reporting fair or poor general health and 14 or more days of poor physical health in the past 30 days. Transgender participants in low tally states also had greater odds of reporting fair or poor general health. Discussion: Lesbian, gay, bisexual, and transgender adults have significantly greater risk of poor health if they live in a state with fewer LGBT anti-discriminatory policies enacted.
Determination of ash content in silicon dioxide filled epoxy-phenolic prepreg using near infrared spectroscopy
Authors: Wu Yi-Hui , Li Dan 
Published: July 2022

This paper presents an application of near infrared spectroscopy associated with partial least squares regression calibration, for ash content analysis of prepreg in the manufacturing progress of copper clad laminate for printed circuited boards. The performance of the model was assessed by cross validation and external validation. The correlation coefficient and the root mean squared error of calibration and validation were 0.99, 0.25% and 0.98, 0.34%, and the measurement process was accomplished in less than 2 min compared to over 60 min for traditional thermo gravimetric analyzsis. The paired t-test results revealed that there was no significant difference between the two methods.
Are recent trends in poverty and deprivation in Australia consistent with trickle-down effects?
Authors: Saunders Peter , Naidoo Yuvisthi , Wong Melissa 
Published: July 2022

AbstractThis article examines trends in social disadvantage in Australia over the decade to 2018 using two approaches: a monetary approach using poverty and a living standards approach using deprivation. We compare the two approaches, highlight their implications and assess whether the evidence produced by each is consistent with trickle-down effects. The estimates allow for variations in thresholds, the treatment of housing costs and relative and absolute measures. The findings indicate an overall decline in poverty that is dependent on the treatment of housing costs and a more consistent decline in deprivation but with little or no improvement for many experiencing poverty or deprivation. Poverty and deprivation among unemployed households were above those for people in other labour force states throughout the period and while these differentials have narrowed, the findings suggest that trickle-down effects did not reach many of those highly disadvantaged or are subject to long delays.
Vibratory Anesthesia’s Effect on Pain Perception in Upper Extremity Corticosteroid Injections
Authors: Weeks Dexter W. , Faillace John J. 
Published: July 2022

Background: Prior studies have investigated the use of vibratory anesthesia for injectional pain reduction in dental, ophthalmologic, and plastic surgery literature. Scarce research has been aimed at determining the effect of vibratory anesthesia on hand and upper extremity injections. It is common practice for surgeons to use vapocoolant spray prior to injection, but there is no strong evidence to support its widespread use. No prior studies have performed a head-to-head analysis of vibratory anesthesia versus vapocoolant spray effect on injectional pain. We hypothesized that both vibratory anesthesia and cold spray anesthesia decrease patient-reported pain of corticosteroid injections compared with injection without anesthesia. Methods: We performed a randomized, prospective study to compare patient-reported pain of injection when the participants were randomly assigned to 1 of the 3 groups: injection without anesthesia, injection with vapocoolant(cold) spray, and injection with vibratory anesthesia. All participants completed a preinjection survey to assess the expected pain of injection and an identical postinjection survey to assess the actual perceived pain. Results: Sixty injections were performed in each intervention, for a total of 180 injections. We found that both vapocoolant spray and vibratory anesthesia decreased patient-reported injection pain compared with no intervention, but only vibratory anesthesia reached statistical significance. Conclusion: Vibratory anesthesia is a useful adjunct for injections of the hand and upper extremity, as has been demonstrated in other specialties’ literature. Although our statistical findings on vapocoolant spray are consistent with prior studies, there may still be clinical benefit in its application.
Understanding Barriers and Facilitators to Physical Activity Engagement to Inform a Precision Prescription Approach during Pregnancy
Authors: Sparks Joshua R. , Flanagan Emily W. , Kebbe Maryam , Redman Leanne M. 
Published: July 2022

Physical activity during pregnancy is an important health behavior. However, many pregnant individuals are provided with little-to-no guidance to adequately engage in physical activity. The purpose of this quantitative and quasi-qualitative study of currently or previously pregnant women was to examine physical activity behaviors in pregnancy and understand barriers and facilitators to achieving physical activity recommendations. Overall, 431 women (18+ years), White/Caucasian (84.5%), married (84.9%), and currently pregnant (66.6%), completed an online survey study. Most women (69.4%) reported engaging in cardio-based physical activity and willing to engage in physical activity to meet guidelines between 2 and 5 days per week (77.4 –88.8%). The most frequently reported barriers were feeling too tired (72.8%) or uncomfortable (71.8%) and childcare needs (57.8%). Being able to choose time of day (96.0%), accessing home workouts (92.9%), and having a personalized prescription (95.6%) were the most reported facilitators. Open comment feedback resulted in additional barriers, such as ensuring proper energy intake, while motivation and support from other pregnant individuals were fundamental facilitators. Individualized physical activity prescription is lacking in routine prenatal care. To support pregnant individuals to achieve physical activity recommendations, developing a prescription with suitable modalities, at-home options, and consideration for physical activity timing are required.
Is Engagement in Physical Activity Related to Its Perceived Mental Health Benefits Among People With Depression and Anxiety? A Population-Scale Survey Study
Authors: Onyeaka Henry , Zambrano Juliana , Szlyk Hannah , Celano Christopher , Baiden Philip , Muoghalu Chioma , Enemuo Valentine , Oghenetega Esther Ayisire , Huffman Jeff. C , Torous John , Firth Joseph 
Published: July 2022

Objective: To examine the prevalence of awareness of PA (physical activity) benefits among those with mental disorders and explore how this is related to actual PA levels in this population. Methods: We queried data from the Health Information National Trends Survey 2019. A sample of 1,139 adults with self-reported depression and anxiety (61% female; mean age of 52.5 years) was analyzed. Multivariable logistic regression was employed to investigate the association between awareness that PA benefits mental health and respondents’ levels of PA. Results: Of the entire sample, a total of 904 individuals (80.9%) endorsed awareness that PA helps reduce symptoms of depression and anxiety. In multivariable analysis, awareness that PA improves mental health was significantly associated with greater odds of being less sedentary (OR 2.31; P = 0.025) and meeting national recommendations for weekly physical activity (OR 2.35; P = 0.046). Conclusion: Overall, findings from this nationally representative survey data indicates that about 4 in 5 adults living with depression and anxiety in the United States endorsed awareness of the mental health benefits of PA. Furthermore, we found that the awareness of these benefits is related to PA engagement.
Does registered nurse involvement in improving healthcare services, influence registered nurse retention?
Authors: Robinson Jane , Engward Hilary , Godier-McBard Lauren , Jones Kerry 
Published: July 2022

Background Registered nurses are ‘critical’ to population health, international responses to emergencies, epidemics and disasters. Retention of registered nurses (RNs) is an international nursing priority. In England, RNs are encouraged to be involved in improving healthcare services. This benefits quality of care, operational and financial performance. However, RN involvement in improvement may reduce RN retention. It is important to understand this relationship when developing effective RN retention strategies. Aim The purpose of this research is to describe possible relationships between RN involvement in improving healthcare services and RN retention, using published 2018 data for National Health Service (NHS) Trusts in England. Methods The relationship between RN involvement in improving healthcare services and RN retention was explored using a correlational design, involving secondary data from the annual NHS Staff Survey and Model Hospital. Results In mental health NHS Trusts in England, a statistically significant, positive correlation of 0.24 was found between RN ‘ab(ility) to make suggestions for improvement’ and RN retention. In mental health NHS Trusts, a statistically significant correlation of 0.278 was found between RNs ‘making improvements happen’ and RN retention. In acute NHS Trusts in England, a statistically significant, negative correlation of −0.15 was identified between RNs ‘mak(ing) improvements happen’ and RN retention. Conclusions The findings suggest that RN retention factors in mental health and acute NHS Trusts differ from community and specialist NHS Trusts in England. This is an important consideration for national RN retention programmes as a single approach to RN retention may not be effective across all healthcare settings.
The Application of Digital Frailty Screening to Triage Nonhealing and Complex Wounds
Authors: Mishra Ram Kinker , Bara Rasha O. , Zulbaran-Rojas Alejandro , Park Catherine , Fernando Malindu E. , Ross Jeffrey , Lepow Brian , Najafi Bijan 
Published: July 2022

Objective: We investigated the association between the complexity of diabetic foot ulcers (DFUs) and frailty. Research Design and Methods: Individuals (n = 38) with Grade 2 Wagner DFU were classified into 3 groups based on the Society for Vascular Surgery risk-stratification for major limb amputation as Stage 1 at very low risk (n = 19), Stage 2 at low risk (n = 9), and Stage 3 to 4 at moderate-to-high risk (n = 10) of major limb amputation. Frailty status was objectively assessed using a validated digital frailty meter (FM). The FM works by quantifying weakness, slowness, rigidity, and exhaustion over a 20-second repetitive elbow flexion-extension exercise using a wrist-worn sensor. FM generates a frailty index (FI) ranging from 0 to 1; higher values indicate progressively greater severity of frailty. Skin perfusion pressure (SPP), albumin, and tissue oxygenation level (SatO2) were also measured. One-way analysis of variance (ANOVA) was used to identify group effect for wound complexity. Pearson’s correlation coefficient was used to assess the associations with frailty and clinical endpoints. Results: Frailty index was higher in Stage 3 and 4 as compared to Stage 1 ( d = 1.4, P < .01) and Stage 2 ( d = 1.2, P < .01). Among assessed frailty phenotypes, exhaustion was correlated with SPP ( r = −0.63, P < .01) and albumin ( r = −0.5, P < .01). Conclusion: Digital biomarkers of frailty may predict complexity of DFU and thus triage individuals who can be treated more simply in their primary clinic versus higher risk patients who require prompt referral to multidisciplinary, more complex care.
Effects of continuous hypoxia on flow-mediated dilation in the cerebral and systemic circulation: on the regulatory significance of shear rate phenotype
Authors: Ogoh Shigehiko , Washio Takuro , Stacey Benjamin S. , Tsukamoto Hayato , Iannetelli Angelo , Owens Thomas S. , Calverley Thomas A. , Fall Lewis , Marley Christopher J. , Bailey Damian M. 
Published: July 2022

AbstractEmergent evidence suggests that cyclic intermittent hypoxia increases cerebral arterial shear rate and endothelial function, whereas continuous exposure decreases anterior cerebral oxygen (O2) delivery. To examine to what extent continuous hypoxia impacts cerebral shear rate, cerebral endothelial function, and consequent cerebral O2 delivery (CDO2), eight healthy males were randomly assigned single-blind to 7 h passive exposure to both normoxia (21% O2) and hypoxia (12% O2). Blood flow in the brachial and internal carotid arteries were determined using Duplex ultrasound and included the combined assessment of systemic and cerebral endothelium-dependent flow-mediated dilatation. Systemic (brachial artery) flow-mediated dilatation was consistently lower during hypoxia (P = 0.013 vs. normoxia), whereas cerebral flow-mediated dilation remained preserved (P = 0.927 vs. normoxia) despite a reduction in internal carotid artery antegrade shear rate (P = 0.002 vs. normoxia) and CDO2 (P < 0.001 vs. normoxia). Collectively, these findings indicate that the reduction in CDO2 appears to be independent of cerebral endothelial function and contrasts with that observed during cyclic intermittent hypoxia, highlighting the regulatory importance of (hypoxia) dose duration and flow/shear rate phenotype.
Attention to renal involvement: report of 17 Joubert syndrome cases in children of a single center in China
Authors: Ying Liang , Hui Wang , FuQian  , Nan Zhou , Yeping Jiang , Lan Mi 
Published: July 2022

Abstract
Background
Joubert Syndrome (JS) is a rare genetic developmental disorder. We are aiming for increasing awareness of this disease especially kidney involvement in children with JS.

Methods
Clinical and genetic data of 17 cases of JS in Beijing children’s hospital in the past 21 years were collected retrospectively.

Results
Twelve males and 5 females, aged from 12d to 15y8m. The most common involvement was neurological system involvement. The second most common involvement was renal involvement: end stage kidney disease in 6 cases (35%), hematuria in 5 cases (29%), proteinuria in 5 cases (29%), renal diffuse lesions in 4 cases (24%), renal cystic lesions in 2 cases (12%), and echogenic enhancement of parenchyma in 2 cases (12%). 10 cases did genetic tests. 3 cases with renal deficiency all had RPGRIP1L gene mutation.

Conclusions
The most common involvement of JS is neurological involvement, and the second is renal involvement. Pediatricians should improve awareness of JS and conduct systemic evaluation of children. More attention should be paid to renal involvement which may be onset hidden but fatal. Early recognition and diagnosis are the goals to delay the start to dialysis and improve quality of patients’ life. The RPGRIP1L gene mutation maybe the most common gene mutation in JS and may have correlations with renal involvement.
SARS-CoV-2 Catalonia contact tracing program: evaluation of key performance indicators
Authors: Herrero Mercè , Ciruela Pilar , Mallafré-Larrosa Meritxell , Mendoza Sergi , Patsi-Bosch Glòria , Martínez-Solanas Èrica , Mendioroz Jacobo , Jané Mireia ,   Epidemiological Surveillance Network of Catalonia, Carmona Parcerisa Gloria , Martinez Mateo Ana Isabel , Pequeño Saco Sandra , Leon Garcia Agata Raquel , Domenech Elisabet , Pericas Escalé Carles , Barrabeig Fabregat Irene , Rovira Faixa Ariadna , Carol Torrades Mònica , Guadalupe Fernandez Victor , Bes Montalat Nuria , Follia Alsina M. Nuria , Ferras Prats Joaquim , Minguell Verges Sofía , Ferrús Serra Gloria , Godoy Garcia Pere , Alseda Graells Miquel , Parron Bernabe Ignacio , Cirera Viladot Anna , Rius Gibert Cristina , García de Olalla Rizo Patricia , Pérez Albarracín Glòria , Sala Farre Maria-Rosa , Clotet Romero Laura , Herrero Garcia Mercè , Ciruela Navas Pilar , Mallafré-Larrosa Meritxell , Mendoza Funes Sergi , Patsi-Bosch Glòria , Martínez-Solanas Èrica , Mendioroz Peña Jacobo , Jané Checa Mireia 
Published: July 2022

Abstract
Background
Guidance on SARS-CoV-2 contact tracing indicators have been recently revised by international public health agencies. The aim of the study is to describe and analyse contact tracing indicators based on Catalonia’s (Spain) real data and proposing to update them according to recommendations.

Methods
Retrospective cohort analysis including Catalonia’s contact tracing dataset from 20 May until 31 December 2020. Descriptive statistics are performed including sociodemographic stratification by age, and differences are assessed over the study period.

Results
We analysed 923,072 contacts from 301,522 SARS-CoV-2 cases with identified contacts (67.1% contact tracing coverage). The average number of contacts per case was 4.6 (median 3, range 1–243). A total of 403,377 contacts accepted follow-up through three phone calls over a 14-day quarantine period (84.5% of contacts requiring follow-up). The percentage of new cases declared as contacts 14 days prior to diagnosis evolved from 33.9% in May to 57.9% in November. All indicators significantly improved towards the target over time (p < 0.05 for all four indicators).

Conclusions
Catalonia’s SARS-CoV-2 contact tracing indicators improved over time despite challenging context. The critical revision of the indicator’s framework aims to provide essential information in control policies, new indicators proposed will improve system delay’s follow-up. The study provides information on COVID-19 indicators framework experience from country’s real data, allowing to improve monitoring tools in 2021–2022. With the SARS-CoV-2 pandemic being so harmful to health systems and globally, is important to analyse and share contact tracing data with the scientific community.
COVID-19 information and self-protective behaviors among rural communities in tropical forests
Authors: Takasaki Yoshito , Coomes Oliver T. , Abizaid Christian 
Published: July 2022

Abstract
Background
Health risk communication plays a key role in promoting self-protective measures, which are critical in suppressing COVID-19 contagion. Relatively little is known about the communication channels used by rural poor populations to learn novel measures and their effectiveness in promoting self-protective behaviors. Behavioral change can be shaped by people’s trust in government institutions which may be differentiated by social identity, including indigeneity.

Methods
During an early phase of the pandemic, we conducted two telephone surveys with over 460 communities – both Indigenous and mestizo – without road access and limited communication access in the Peruvian Amazon. This is the first report on the association of information sources about self-protective measures against COVID-19 with the adoption of self-protective behaviors in remote rural areas in developing countries.

Results
People mainly relied on mass media (radio, television, newspapers) and interpersonal sources (local authorities, health workers, neighbors/relatives) for information and adopted handwashing, mask-wearing, social distancing, and social restrictions to varying degrees. Overall, self-protective behaviors were largely positively and negatively associated with mass media and interpersonal sources, respectively, depending on the source-measure combination. Mistrust of the government seems to have shaped how Indigenous and mestizo peoples distinctively responded to interpersonal information sources and relied on mass media.

Conclusions
Our findings call for improved media access to better manage pandemics in rural areas, especially among remote Indigenous communities.