bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of Ready-to-Cook Functional Food Formulations Based on Cereals and Pulses for Elevated Nutritional, Nutraceutical and Antioxidant Activities
Authors: Chaya Hulegaru Channakeshava , Ku Sandopu Sravan , Jayarama Shankar , Paramesha Mahadevappa 
Published: December 2022

Abstract
Despite their high nutritional and potential health benefits, cereals and pulses intake has not been increased in the last three decades. Several ready-to-eat (RTE) or ready-to-cook (RTC) formulations were implemented to overcome this and increase their consumption in bakery and snack products. In the present study, we selected five (5) different cereals and pulses, i.e., barley, finger millet, chickpeas, green gram, and horse gram, along with skimmed milk and unripe banana, and arrowroot powder, for the development of functional food formulations. The LC-HRMS/MS confirmed a total of 22 compounds with the MS/MS fragment ions for rutin, quercetin rhamnoside, quercetin-3-xyloside, chlorogenic acid, p-coumarylquinic acid, coumaric acid hexoside, epicatechin, ferulic acid, gallic acid, vanillic acid, protocatechuic acid, and trans-cinnamic acid respectively. A dose-dependent antioxidant potential against TAA, FRAP, DPPH, and ABTS radicals. Hence, the RTC formulations could merit balanced nutritional and nutraceutical needs of the growing malnourished population as sustainable, functional foods.
Exploring the Quality of Nexus among the College-going Older Adolescents with their Parents in Bangladesh: A Public Health Perspective
Authors: Chowdhury Farhana Ishrat , Hossain Syed Billal , BakiBillah Abul Hasan , Khan Ayub , Shahjahan Md. , Chowdhury ABM Alauddin 
Published: December 2022

Abstract
This study aims to investigate the relationship between parental bonding and parent-child relationships among the college-going adolescents. A scale suggested by Robert C. Pianta (1992) was used in this quantitative, cross-sectional study with a descriptive design. Among 1000 students of Chattogram Biggan College and Chattogram Commerce College in Chattogram, Bangladesh, 101 individuals were selected. The demographic profile of the participants; 46% of the respondents were male and 54% were female, all of them were aged between 17 to 19. In terms of feelings about spending time with parents, it was discovered that 62.4% of the total 101 participants are very satisfied with their mother, while 49% are very happy with their father. While 5.9% and 3% of participants are unhappy and very unhappy with their mothers, just 3.5% of the total participants are unhappy with their fathers. While a large proportion (almost 40%) have a strong bond with their mother. On the other hand, over three-quarters of respondents have disagreements with their fathers' proximity and dependence, according to the research. While a sizable proportion (about 30%) have a strong bond with their father. Whereas over 40% of respondents calculated overall intimacy with their father was low, and nearly 30% with their mother, the remaining respondents were either medium or highly intimate with their parents. Overall relationship intimacy with mothers and fathers was also found to be linked to various relationship characteristics such as conflict (P < 0.000), closeness (P < 0.000) and dependence (P < 0.000) according to the findings. Things that participants like (P-value = 0.047) and dislike (P-value = 0.040) most about mother, feelings when spending time with mother (P-value = 0.066), and things that dislike most about father (P-value = 0.058) had a marginally significant connection with gender.
A fully implicit parallel solver for MHD instabilities in a tokamak
Authors: Yao Qinghe , Jiang Zichao , Jiang Junyang , Ma Zhiwei 
Published: December 2022

Abstract
Aiming at the long-term and high-precision simulation of the magnetohydrodynamic (MHD) instabilities in the tokamak model, we developed a parallelized solver based on a fully implicit difference scheme. A 4th-order precision difference scheme and the Newton-Krylov method are employed in the proposed solver for both the flow and the electromagnetic field. To achieve high parallel efficiency, we adopt a strategy based on the spatial domain decomposition to partition the large Jacobian matrices in the iteration, and a buffer area based on the grid density is utilized to minimize the memory and time consumption. The accuracy of the methodology is verified, and the numerical results are validated by comparison with recognized results. The numerical results of the tearing mode instability in the tokamak model have demonstrated the precision and reliability of the algorithm, and the high parallel efficiency has been proven by the scalability test on the platform with up to 1280 threads, showing significant potential in the large-scale simulation of MHD problems.
Association Between Urinary Heterocyclic Aromatic Amines and Mortality in Adults
Authors: Zhang Yali , Yu Liang , Lin Xingyu , Zhou Ren , Xu Qi , Zhao Hailei 
Published: December 2022

Abstract
Heterocyclic aromatic amines (HAA) are mutagenic compounds; however, their long-term effects on humans remain poorly studied. This study investigated the association between HAA concentration and mortality in adults. Data from the National Health and Nutrition Examination Survey 2013-2014 were linked to mortality data from 2019 and analyzed using Cox regression analysis to determine the association of different HAA with all-cause, cardiovascular disease (CVD), and cancer mortality. Age, sex, education level, race, poverty income ratio, body mass index, smoking status, drinking status, and serum cotinine were included as covariates in three different Cox regression models. This study included 1,713 adults with a median age of 47 years (49.5% men). During a median follow-up at 71 months, 100 deaths occurred. Owing to detection limits, only four had discernible detection rates and were included in our analysis. Among them, only norharman concentration was significantly associated with all-cause and CVD mortality. The hazard ratio (HR) was 1.50 (95% confidence interval: 1.10–2.04) for all-cause mortality when analyzing norharman concentration as a natural log-transformed continuous variable and 3.33 (95% confidence interval: 2.24–4.95) for CVD mortality. Associations remained consistent when norharman concentrations were analyzed as binary variables (split by median). Urinary harman concentration seemed to show a negative association with cancer mortality. No definitive evidence was found of an association between other HAA and mortality. Urinary norharman concentration is associated with all-cause mortality and CVD mortality in adults.
Nanoscopic Lignin Mapping on Cellulose Nanofiber via Scanning Transmission Electron Microscopy and Atomic Force Microscopy
Authors: Morita Kenta , Takenaka Musashi , Tomita Kohei , Ishii Jun , Kawaguchi Hideo , Murakami Daisuke , Matsumoto Takuya , Nishino Takashi , Ogino Chiaki 
Published: December 2022

Abstract
Cellulose has been developed as an alternative to petrochemical materials. By comparison with refined nanofiber (RCNF), lignocellulose nanofiber (LCNF) shows particular promise because it is produced from biomass using only mild pretreatment. The mechanical properties of LCNF depends on the contained lignin. However, the microscopic location of the lignin contained in LCNF has not been determined. Thus, we developed two methods to detect and visualize lignin. One uses a scanning transmission electron microscope (STEM) equipped with an energy dispersive X-ray spectroscopy (EDS) detector. The other method uses an atomic force microscope (AFM) equipped with a cantilever coated with an aromatic molecule. Both methods revealed that the lignin in LCNF covers a thin cellulose fiber and is precipitated in a grained structure. In particular, the AFM system was able to determine the nanoscopic location of lignin-rich areas. The present study establishes a strong tool for analyzing the characteristics of lignin-containing materials.
Identification of circulating myeloid cells as a potential diagnosis and recurrence marker of pancreatic ductal adenocarcinoma through the single-cell analysis
Authors: Lee Hyung Keun , Kim So Young , Chung Soo-Hyun , Choi Bongkun , Jang Sung Ill , Yoi Arum , Kang Hyun Goo , Lee Jusung , Choi Yoon Ha , Park Joon Seong , Kim Jong Kyoung , Chang Eun-Ju , Lee Dong Ki 
Published: December 2022

Abstract
Background:
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy with a poor survival rate, largely due to the lack of biomarker for early detection. Given the crucial roles of circulating and tumor-infiltrating myeloid cells in PDAC progression, the identification of specific subsets of them can be a biomarker in liquid biopsies for diagnosis and prediction of recurrence risk of PDAC.
Methods:
We analyzed PDAC tissue microarray by immunohistochemistry to measure cytokine expressions. Peripheral blood cells of PDAC patients were subjected to define distinct cell population of PDAC patients by single-cell RNA sequencing and flow cytometry. In addition, the presence of myeloid cells was analyzed by murine xenograft/orthotropic models of PDAC cell lines. Finally, we performed a clinical study to evaluate the correlation of IL-10R2 expression and PDAC diagnosis or recurrence.
Results:
We found enriched IL-10R2+/IL-22R1 + myeloid cells in peripheral blood from PDAC patients, and that they display a signature association with tumor-educated monocytes. In addition, we verified the positive correlation of pancreatic tumor growth with increased IL-10R2+/IL-22R1 + myeloid cells through the murine xenograft/orthotropic models. Most importantly, the IL-10R2 + myeloid cells signaled tumor recurrence 130 days faster than CA19-9 in post-pancreatectomy patients.
Conclusions:
Enriched IL-10R2 + myeloid cells in PDAC patient’s blood may benefit uncomplicated and effective diagnostic marker and indicator of recurrence.
Enumeration of plant-growth promoting bacteria Herbaspirillum seropedicae viable cells by a new propidium monoazide combined with quantitative PCR (PMA-qPCR) assay
Authors: Pedrolo Ana Marina , Cunha Elisandra Triches , Gnecco Nicolle , Arisi Ana Carolina Maisonnave 
Published: December 2022

Abstract
The plant growth-promoting bacteria Herbaspirillum seropedicae is an endophytic diazotroph found in several economically important crops. Reliable, high-yield, and cost-effective methods are needed to determine bacterial viability in inoculant formulations or in plant. The present study aims to develop a PMA-qPCR assay to evaluate viable cells of H. seropedicae in pure culture and maize roots grown in vitro. H. seropedicae grown in a culture medium was submitted to heat treatment at 48°C for different periods of time. Maize roots were inoculated, grown in vitro and collected seven days after inoculation. The bacteria viable cells were quantified using qPCR, PMA-qPCR assays, and plate counting. Standard curves were prepared, and the efficiency obtained ranged from 85 to 99%. The limit of detection (LOD) was 101 genome copies, corresponding to 60.3 pg of DNA. Enumeration obtained in pure cultures by qPCR, PMA-qPCR and plate count were 8.85 ± 0.16, 6.51 ± 0.12 and 2.25 ± 0.30 log CFU.mL− 1 after heat treatment, respectively. These results showed that PMA-qPCR is a powerful approach for quantifying viable and viable but non-culturable cells in inoculants and plants. PMA-qPCR allowed reliable obtained results much faster than culture-dependent methods.
Attitude and practice of Yemeni physicians toward the integration of herbal medicines into patient care practice
Authors: Al-Worafi Yaser Mohammed , Ming Long Chiau 
Published: December 2022

Abstract
Objectives
The aim of this study was to explore the attitude and practice of Yemeni physicians toward the integration of herbal medicines into patient care practice and the factors affecting the attitude and practice.
Methods
A cross-sectional study was conducted over a period of four months, from January 2019 to April 2019, among physicians in Sana’a, Yemen.
Results
A total of 25 physicians were interviewed. There were males, and the mean age was 39.84 ± 6.95 years. The finding of this study showed that the study physicians used herbal medicine on a daily and weekly basis for many reasons. The findings of this study show that the attitude of 56 % was positive towards the integration of herbal medicines. Furthermore, they recommended herbal medicines to their patients. The attitude and practice were influenced by many factors, such as the severity of the disease/condition, evidence-based/rationality of using herbal medicines, and experience/personal use.
Conclusion
Herbal medicine use was common among physicians in Yemen. More than half of this study participants had a positive attitude towards integrated herbal medicines, and they recommended herbal medicines to their patients.
ACE2 Receptor Polymorphism and its Correlation with Anti-SARS-CoV-2
IgM Antibodies - A Case-Control Study
Authors: Yahya Saira , Siraj Anum , Khan Amber , Awan Saleem 
Published: December 2022

Background:
The SARS-CoV-2 pandemic originated in Wuhan, China in December 2019
and spread rapidly worldwide. The virus gets entry into target cells via angiotensin-converting enzyme
2 (ACE2) receptors and its gene is highly polymorphic.

Introduction:
The variations in SARS-CoV-2 susceptibility and severity can be explained on a genetic
level by studying the polymorphism in ACE2 receptor polymorphism.

Objective:
A prospective case-control study was designed to compare the ACE2 levels in SARS-CoV-
2 patients with the healthy controls in the local population, for which a total of 100 EDTA-containing
blood samples were included (50 SARS-CoV-2 IgM positive case and 50 healthy controls).

Methods:
PCR-RFLP was performed to investigate the polymorphism of ACE2 in genomic DNA and
the ACE2 plasma levels were determined through ELISA.

Results:
No significant difference in allelic and genotype frequencies (GG, GA, AA) were observed
while the ACE2 plasma levels were found to be decreased in positive samples.

Conclusion:
No significant association of the ACE2 gene polymorphism (G8790A) was found with
the SARS-CoV-2 susceptibility in the Pakistani population which intimates the search for other genetic
factors within the local population.
Prediction of Recurrence of Atrial Fibrillation Post-ablation Based on
Atrial Fibrosis Seen on Late Gadolinium Enhancement MRI: A Metaanalysis
Authors: Regmi Manjari Rani , Bhattarai Mukul , Parajuli Priyanka , Botchway Albert , Tandan Nitin , Abdelkarim Jumana , Labedi Mohamed 
Published: December 2022

Objectives:
This meta-analysis aims to investigate the recurrence of atrial fibrillation
(AF) post-ablation based on the various stages of fibrosis seen in the late gadolinium enhancement
magnetic resonance imaging (LGE-MRI).

Methods:
Electronic databases were searched using specific terms and identified nine studies that
met the inclusion criteria. A total of 1,787 patients underwent LGE-MRI to assess atrial fibrosis
before catheter ablation for AF. We performed three analyses: first, we compared stage IV versus
stage I (reference group). The second set examined the combined stages III and IV versus stages I
and II (reference group). The third set compared stage IV versus combined stages I, II, and III. The
metanalysis relied on a random-effects model to pool the odds ratios (OR) and 95% confidence intervals
(CI) using the DerSimonian and Laird method. The data was analyzed using StatsDirect
software in England.

Results:
The study showed a higher rate of AF recurrence after ablation in stage IV atrial fibrosis
than in stage I (OR, 9.54; 95% CI, 3.81 to 28.89; P<00001). Also, in patients with combined stages
III & IV of atrial fibrosis, AF recurrence was significantly higher after ablation than in stages I &
II groups (OR, 2.37; 95% CI, 1.61 to 3.50; P<00001). Similarly, compared to combined stages I,
II, and III, patients with stage IV have higher odds of recurrence post-ablation (OR, 4.24; 95% CI,
2.39- 7.52, P < 0.001).

Conclusion:
This metanalysis demonstrates the strong association between left atrial fibrosis in
LGE-MRI and AF post-ablation recurrence. The finding of this study will further assist clinicians
in predicting the recurrence rate of AF based on the amount of fibrosis and tailor therapeutic decisions
for further management.
Estándares del sistema interamericano en relación al derecho a un recurso efectivo
Authors: Dávila Pérez Martha Elba 
Published: December 2022

La actividad jurisdiccional se revela como aquella dirigida a resolver las controversias que surgen entre particulares o entre particulares y entes públicos. Esta actividad tiene dos finalidades: el aseguramiento del orden jurídico; y, la realización de dos valores, la seguridad y la justicia. El derecho a un recurso efectivo previsto en el artículo 25 de la Convención Americana sobre Derechos Humanos es un derecho en sí mismo y un instrumento para ejercer la defensa de otros derechos y ha sido materia de frecuentes pronunciamientos por parte de la Comisión y la Corte Interamericana de Derechos Humanos. Esta jurisprudencia conviene que sea sistematizada para establecer los requisitos mínimos con los que debería contar un recurso para que pueda ser considerado efectivo para la protección de los derechos humanos. PALABRAS CLAVES: Recurso efectivo – Protección judicial – Estándares Interamericanos – Sistema Interamericano de Derechos Humanos – Corte Interamericana de Derechos Humanos – Comisión Interamericana de Derechos Humanos
Entangled Tangos: Passionate Displays, Intimate Dialogues
Authors: Cara Ana C. 
Published: December 2022

Abstract
While tango is known internationally, it is not a universal dance. The home tango and export tango exemplify the coexistence of distinct but entangled tango traditions. Together these practices have been central in giving Argentines a cultural and political voice, as well as economic agency, both at home and globally.
Routes to Roots: Searching for the Streetlife of Memory
Authors: Dyen Doris J. 
Published: December 2022

Abstract
Routes to Roots: Searching for the Streetlife of Memory looks at the challenge of creating a driving guide whose aim is to enable visitors to discover and experience the folklife of a region previously unused by visitors, a region whose folklife, while vital and significant, is now often invisible even to residents’ eyes. The driving guide’s primary purpose was to encourage community revitalization through cultural tourism, but it evolved beyond that into a way of telling the region’s industrial story though its folklife sites, events, and activities. The author explores how members of the interdisciplinary project team influenced each other as the project progressed through the stages of conception, research, and design and how the resulting travel guide both fulfilled and reinterpreted the project’s original mission.
Performance de um corpo ao avesso
Authors: Takaesu Emily Mayumi 
Published: December 2022

O presente artigo pretende abordar a ideia de dispêndio ligada à experiência artística. Investigaremos os fundamentos da violência, dos interditos e da transgressão com base nas proposições filosóficas de Georges Bataille. Nesse sentido, tomamos como referência artística a obra do artista austríaco Hermann Nitsch, que resgata elementos mitológicos e religiosos de celebração e afirmação profunda da existência pela via da sublimação do sofrimento. Tal sublimação se daria no enfrentamento da morte através do caráter simbólico dos dispositivos de seu “Teatro das Orgias e Mistérios” (Das Orgien Mysterien Theater).
PALAVRAS-CHAVES: dispêndio; performance; morte; erotismo.
Algumas questões estéticas e políticas nos murais zapatistas: um ensaio de interpretação fotográfica
Authors: Hilsenbeck Filho Alexander Maximilian 
Published: December 2022

Nos ocuparemos sobre alguns conteúdos presentes nos murais em territórios zapatistas, especificamente no Caracol de Oventik. O que pretendemos aqui é articular uma discussão sobre o que retrata-se em alguns murais zapatistas e como essas imagens refletem as concepções histórias e políticas do movimento.
Can policy coordination facilitate unimpeded trade? An empirical study on factors influencing smooth trade along the Belt and Road
Authors: Yu Zhenni , Yu Jian 
Published: December 2022

Abstract
There are 94 countries and regions along the Belt and Road (CRBR). China proposed the Belt and Road Initiative (BRI) in 2013, and it encompasses five core elements: unimpeded trade (UT), policy coordination (PC), infrastructure connectivity (IC), financial integration (FI) and people-to-people bond (PPB). The BRI has facilitated international relations and multilateral trade, in addition to building a community with a shared future for mankind. However, factors such as political relations and cultural distance have affected bilateral trade (BT) between China and CRBR. Further analysis is required to explore the association between UT and policy, infrastructure, financial and people-to-people connectivity. A multiple linear regression analysis using SPSS 20 revealed that: (1) IC, FI, PPB and improved economic levels can promote BT to varying degrees, but spatial distance inhibits the development of BT; and (2) the coordination between policy subjects does not promote UT up to any significant level. Accordingly, strengthening infrastructure and FI, promoting people-to-people and bilateral exchanges, and opening extra China–Europe freight trains and maritime transport will enhance UT, expand BT and invigorate the global economy.
Computer Aided Design Process for Hydraulic Servo
Authors: Ułanowicz Leszek , Sabak Ryszard 
Published: December 2022

Abstract
This study presents a method of computer support for the design of a hydraulic servo dedicated to the aircraft control system. A 3D geometric model of the servo was developed, which enabled the simulation of its kinematics. The paper presents a simulation model of a hydraulic servo that enables simulation of the dynamics of its mechanisms. The servomechanism model takes into account the dynamics of the movement of the distributor slider and the dynamics of the actuator piston rod movement under the influence of forces occurring in the servo. As a result of the simulation, step characteristics and static characteristics of the servo response were obtained. The presented model makes it possible to visualize the dynamics of operation of the prototype servo in various modes of its operation with different parameters of its control. It allows you to quickly and conveniently test the concept of an hydraulic servo and evaluate its functioning.
Technology of Making Airfield Pavements in Relation to the Existing Requirements in Terms of Texture
Authors: Wesołowski Mariusz , Blacha Krzysztof , Włodarski Piotr 
Published: December 2022

Abstract
The assessment of the texture of airfield pavements, in addition to assessing their roughness, is a component of the broader concept of anti-skid properties, which significantly affect the safety of air operations. The roughness of the pavement directly affects the adhesion of the aircraft tire to the pavement, and the texture additionally affects the effectiveness of dynamic drainage of water from the pavement. The current standard requirements in terms of roughness and texture of airfield pavements do not distinguish the technology used. In the paper, the authors focused on the analysis of the results in terms of the texture of airfield pavements and presented the resulting conclusions in relation to whether the technology of its implementation has an impact on the texture parameter.