bluuebunny/crossref_metadata_2025_split huggingface dataset:
In vivo through-range passive stiffness of the lumbar spine: a meta-analysis of measurements and methods
Authors: Watt Andrew A. , Callaway Andrew J. , Williams Jonathan M. 
Published: July 2022

Abstract
Passive spinal stiffness is an important property thought to play a significant role in controlling spinal position and movement. Measuring through-range passive stiffness in vivo is challenging with several methods offered in the literature. Currently, no synthesis of values or methods exists to which to compare literature to. This study aims to provide a contemporary review and quantitative synthesis of the through-range in vivo passive lumbar spinal stiffness values for each of the cardinal planes of movement. A structured systematic search, following PRISMA guidelines, of 28 electronic databases was conducted in 2022. Articles were restricted to peer-reviewed English language studies investigating in vivo through-range passive stiffness of the lumbar spine. Thirteen studies were included, ten relating to flexion/extension, four to lateral bending and five to axial rotation. Average stiffness values, as weighted means and confidence intervals, for each of the four sections of the moment-movement curves were synthesised for all planes of movement. Lateral bending was found to be the comparatively stiffest movement followed by flexion and then axial rotation. Future research should focus on the validity and reliability of measurement techniques. Axial rotation would also benefit from further study of its latter stages of range.
Graphical abstract
A Multiscale Mathematical Model of Plasmodium Vivax Transmission
Authors: Anwar Md Nurul , Hickson Roslyn I. , Mehra Somya , McCaw James M. , Flegg Jennifer A. 
Published: July 2022

AbstractMalaria is caused by Plasmodium parasites which are transmitted to humans by the bite of an infected Anopheles mosquito. Plasmodium vivax is distinct from other malaria species in its ability to remain dormant in the liver (as hypnozoites) and activate later to cause further infections (referred to as relapses). Mathematical models to describe the transmission dynamics of P. vivax have been developed, but most of them fail to capture realistic dynamics of hypnozoites. Models that do capture the complexity tend to involve many governing equations, making them difficult to extend to incorporate other important factors for P. vivax, such as treatment status, age and pregnancy. In this paper, we have developed a multiscale model (a system of integro-differential equations) that involves a minimal set of equations at the population scale, with an embedded within-host model that can capture the dynamics of the hypnozoite reservoir. In this way, we can gain key insights into dynamics of P. vivax transmission with a minimum number of equations at the population scale, making this framework readily scalable to incorporate more complexity. We performed a sensitivity analysis of our multiscale model over key parameters and found that prevalence of P. vivax blood-stage infection increases with both bite rate and number of mosquitoes but decreases with hypnozoite death rate. Since our mathematical model captures the complex dynamics of P. vivax and the hypnozoite reservoir, it has the potential to become a key tool to inform elimination strategies for P. vivax.
A Dark Side of Telework: A Social Comparison-Based Study from the Perspective of Office Workers
Authors: Maier Christian , Laumer Sven , Weitzel Tim 
Published: July 2022

AbstractTelework became a necessary work arrangement during the global COVID-19 pandemic. However, practical evidence even before the pandemic also suggests that telework can adversely affect teleworkers’ colleagues working in the office. Those regular office workers may experience negative emotions such as envy which, in turn, can impact work performance and turnover intention. In order to assess the adverse effects of telework on regular office workers, the study applies social comparison theory and suggests telework disparity as a new theoretical concept. From the perspective of regular office workers, perceived telework disparity is the extent to which they compare their office working situation with their colleagues’ teleworking situation and conclude that their teleworking colleagues are slightly better off than themselves. Based on social comparison theory, a model of how perceived disparity associated with telework causes negative emotions and adverse behaviors among regular office workers was developed. The data were collected in one organization with telework arrangements (N = 269). The results show that perceived telework disparity from the perspective of regular office workers increases their feelings of envy toward teleworkers and their job dissatisfaction, which is associated with higher turnover intentions and worse job performance. This study contributes to telework research by revealing a dark side of telework by conceptualizing telework disparity and its negative consequences for employees and organizations. For practice, the paper recommends making telework practices and policies as transparent as possible to realize the maximum benefits of telework.
Rethinking Maker: Hegel's Realism Revisited
Authors: Webster George 
Published: July 2022

AbstractI provide a metaphysically realist interpretation of Hegel’sPhilosophy of Nature—one that allows us to make sense of one of the more puzzling references to nature in hisScience of Logic. I do so by affording William Maker’s under-appreciated account of Hegel’s realism more of the attention and scrutiny it deserves—not least because it involves a distinctively simple and elegant account of the famously obscure move from logic to nature in Hegel’s system. Though I point out its limitations, I claim that Maker’s arguments can be revised in order to recover more of the rigour and complexity of Hegel’s metaphysics.
FOLD-RM: A Scalable, Efficient, and Explainable Inductive Learning Algorithm for Multi-Category Classification of Mixed Data
Authors: WANG HUADUO , SHAKERIN FARHAD , GUPTA GOPAL 
Published: July 2022

AbstractFOLD-RM is an automated inductive learning algorithm for learning default rules for mixed (numerical and categorical) data. It generates an (explainable) answer set programming (ASP) rule set for multi-category classification tasks while maintaining efficiency and scalability. The FOLD-RM algorithm is competitive in performance with the widely used, state-of-the-art algorithms such as XGBoost and multi-layer perceptrons, however, unlike these algorithms, the FOLD-RM algorithm produces an explainable model. FOLD-RM outperforms XGBoost on some datasets, particularly large ones. FOLD-RM also provides human-friendly explanations for predictions.
Strong Equivalence of Logic Programs with Ordered Disjunction: A Logical Perspective
Authors: CHARALAMBIDIS ANGELOS , NOMIKOS CHRISTOS , RONDOGIANNIS PANOS 
Published: July 2022

AbstractLogic Programs with Ordered Disjunction (LPODs) extend classical logic programs with the capability of expressing preferential disjunctions in the heads of program rules. The initial semantics of LPODs, although simple and quite intuitive, is not purely model-theoretic. As a result, certain properties of programs appear non-trivial to formalize in purely logical terms. For example, the current characterization of strong equivalence for LPODs, does not coincide with logical equivalence in some specific logic. This comes in sharp contrast with the well-known characterization of strong equivalence for classical logic programs, which coincides with logical equivalence in the logic of here-and-there. In this paper we obtain a purely logical characterization of strong equivalence for LPODs as logical equivalence in a four-valued logic. Moreover, we provide a new proof of the coNP-completeness of strong equivalence for LPODs, which has an interest in its own right since it relies on the special structure of such programs. Our results are based on the recent logical semantics of LPODs, a fact which we believe indicates that this new semantics may prove to be a useful tool in the further study of LPODs.
Next-Generation Agreements and the WTO
Authors: Claussen Kathleen 
Published: July 2022

AbstractThis paper reviews the trade agreement landscape and argues that the conventional understanding of trade agreements as encapsulated in the WTO Agreements is now outdated. This misperception about trade agreements is not just an institutional insufficiency. Concentration on those agreements has led many practitioners and commentators to underestimate the variable texture of the global trade agreement fabric. But these shortcomings have not inhibited states from concluding innovative alternatives to regulate and manage the cross-border movement of goods and services. As this paper shows, trade-related agreements that do not fit the perceived traditional mold have proliferated. Given these advances, more policy and scholarly attention is required. Accordingly, this paper serves as a roadmap for the accommodation of trade agreements within the WTO and as an agenda for additional research.
Rethinking materialism and Asia: Miki Kiyoshi and Hiromatsu Wataru
Authors: Murthy Viren 
Published: July 2022

AbstractThis paper argues that the interwar Japanese Marxists Miki Kiyoshi and more contemporary Hiromatsu Wataru each moved towards developing this perspective beyond simple distinctions between idealism, which is confined to concepts, and materialism, conceived as presupposing that ideas are determined by matter. Japanese Marxism was in a unique place to affect such a synthesis because of the existence of Kyoto School philosophy, with whom both Miki and Hiromatsu were associated. The proponents of the Kyoto School combined Eastern and Western philosophical perspectives, which had the aim of criticizing modernity. Miki Kiyoshi and other members of the Kyoto School eventually supported Japan's wartime effort, which delegitimized their concerns about modernity during the postwar. However, in postwar Japan, Hiromatsu developed a creative reading of Marx's materialism and in the 1994 surprised everyone by advocating a pan-Asianist critique of modernity. Hiromatsu suggested that despite problems that Miki and the Kyoto School represented, one had to grasp the rational kernel, which could save Marxism from slipping into an equally dangerous modernization theory. This task remains for us today when the dystopia of globalized capitalism seems to have become a reality that threatens the survival of our planet.
Feasibility evaluation of a dual-mode ankle exoskeleton to assist and restore community ambulation in older adults
Authors: Fang Ying , Harshe Karl , Franz Jason R. , Lerner Zachary F. 
Published: July 2022

Abstract

Background
Age-related deficits in plantar flexor muscle function during the push-off phase of walking likely contribute to the decline in mobility that affects many older adults. New mobility aids and/or functional training interventions may help slow or prevent ambulatory decline in the elderly.

Objective
The overarching objective of this study was to explore the feasibility of using an untethered, dual-mode ankle exoskeleton as a mobility aid to reduce energy consumption, and as a resistive gait training tool to facilitate functional recruitment of the plantar flexor muscles.

Methods
We recruited six older adults (68–83 years old) to evaluate acute metabolic and neuromuscular adaption to ankle exoskeleton assistance and to evaluate the potential for ankle resistance with biofeedback to facilitate utilization of the ankle plantar flexors. We also conducted a 12-session ankle resistance training protocol with one pilot participant.

Results
Participants reached the lowest net metabolic power and soleus integrated electromyography (iEMG) at 6.6 ± 1.6 and 5.8 ± 4.9 min, respectively, during the 30-min exoskeleton assistance adaptation trial. Four of five participants exhibited a reduction (up to 19%) in metabolic power during walking with assistance. Resistance increased stance-phase soleus iEMG by 18–186% and stance-phase average positive ankle power by 9–88%. Following ankle resistance gait training, the participant exhibited increased walking speed, endurance, and strength.

Conclusions
Our results suggest that dual-mode ankle exoskeletons appear highly applicable to treating plantar flexor dysfunction in the elderly, with assistance holding potential as a mobility aid and resistance holding potential as a functional gait training tool.
Banding Together in Cape Town and Lagos: Engaging Reciprocity as Applied Ethnomusicology
Authors: BRUINDERS SYLVIA , KUNNUJI JOSEPH 
Published: July 2022

AbstractThis article discusses reciprocity in research as engaged scholarship and, more specifically, applied ethnomusicology. It draws on two ethnographic studies and their associated activism in Cape Town, South Africa and Lagos, Nigeria. The article investigates the histories of engaged scholarship and applied ethnomusicology and suggests that each community requires a method of engagement based on its contextual specifics. Hence, the case studies may be seen to animate workable approaches in different socio-cultural contexts. The paper concludes that these methods may serve as frameworks for developing site-specific strategies of engaged scholarship in other parts of Africa.
Impacts of Changes in Land Use and Land Cover Between 2001 and 2018 on Summertime O3 Formation in North China Plain and Surrounding Areas–A Case Study
Authors: Yu Jiaoyang , Zhou Weijian , Wu Jiarui , Li Xia , Liu Suixin , Wang Ruonan , Liu Lang , Jiang Qian , Tie Xuexi , Li Guohui 
Published: July 2022

AbstractChanges in land use and land cover (LULC) influence meteorological fields and biogenic emissions, further affecting the atmospheric chemistry and air quality. Combining the satellite measurements and WRF‐Chem model simulations, we evaluate the impacts of the LULC change between 2001 and 2018 on the summertime ozone (O3) formation in North China Plain and surrounding areas (NCPs). Satellite measurements have revealed that from Taihang to Yanshan Mountain, the fraction of broadleaf and needle forest coverage has increased by 5%–20% and the urban area has increased by up to 25% in the NCP. Additionally, the vegetation density has increased significantly in the NCPs except for urban areas. The LULC change generally enhances biogenic volatile compounds emissions in the NCPs, particularly over Taihang and Yanshan mountain, but the O3 variation is divergent. The maximum daily 8‐ihr average (MDA8) O3 concentrations are reduced by 1%–7% over Taihang and Yanshan Mountain because the raised vegetation density increases O3 dry deposition velocity to accelerate the O3 loss. The raised vegetation density enhances the evapotranspiration to decrease the near‐surface temperature by 0.1°C–1.5°C, which also generates a divergence in the low‐level atmosphere in the NCPs, causing secondary northerly or easterly winds in the NCP. The O3 enhancement along the coastal areas of the NCP is attributed to the perturbation of wind fields and photolysis induced by the LULC change. The divergent variation of the MDA8 O3 concentrations in the NCP is generally caused by the variations of biogenic emissions and photolysis.
Active Back‐Arc Thrust in North West Java, Indonesia
Authors: Aribowo Sonny , Husson Laurent , Natawidjaja Danny H. , Authemayou Christine , Daryono Mudrik R. , Puji Anggraini R. , Valla Pierre G. , Pamumpuni Astyka , Wardhana Dadan D. , de Gelder Gino , Djarwadi Didiek , Lorcery Manon 
Published: July 2022

AbstractThe Java Back‐arc Thrust scars the entire back‐arc area of Java Island, but the faults' nature, timing, and activity remain partly elusive. Characterizing the structure and activity of the seismogenic Java Back‐arc Thrust (historical earthquakes up to 7 Mw) is a cornerstone to evaluate associated geohazards. We focus on the western part of Java Back‐arc Thrust that reaches the megalopolis of Jakarta. We combine morphotectonic data, seismic reflection, electric resistivity profiles, kinematic, structural field measurements, paleoseismological trenching, and sediment dating (optically stimulated luminescence and14C). Our results suggest that the interplay between the faults, volcanoes, and sedimentary basin modulates the propagation of the fault system across and along‐strike. The West Java Back‐arc Thrust has been active from Pliocene to Recent, but with a laterally variable tempo and tectonic regime. While tectonic activity was sustained for longer times in the eastern part, the West Java Back‐arc Thrust broke through the Jakarta Basin in the west, possibly only since the Late Pleistocene, and partitions into a network of immature transpressive structures. We conclude that the West Java Back‐arc Thrust has a high seismic hazard that requires a careful risk evaluation along its trace, as it threatens the numerous infrastructures of the densely populated West Java.
Heralds of Future Volcanism: Swarms of Microseismicity Beneath the Submarine Kolumbo Volcano Indicate Opening of Near‐Vertical Fractures Exploited by Ascending Melts
Authors: Schmid F. , Petersen G. , Hooft E. , Paulatto M. , Chrapkiewicz K. , Hensch M. , Dahm T. 
Published: July 2022

AbstractThe Kolumbo submarine volcano in the southern Aegean (Greece) is associated with repeated seismic unrest since at least two decades and the causes of this unrest are poorly understood. We present a ten‐month long microseismicity data set for the period 2006–2007. The majority of earthquakes cluster in a cone‐shaped portion of the crust below Kolumbo. The tip of this cone coincides with a low Vp‐anomaly at 2–4 km depth, which is interpreted as a crustal melt reservoir. Our data set includes several earthquake swarms, of which we analyze the four with the highest events numbers in detail. Together the swarms form a zone of fracturing elongated in the SW‐NE direction, parallel to major regional faults. All four swarms show a general upward migration of hypocenters and the cracking front propagates unusually fast, compared to swarms in other volcanic areas. We conclude that the swarm seismicity is most likely triggered by a combination of pore‐pressure perturbations and the re‐distribution of elastic stresses. Fluid pressure perturbations are induced likely by obstructions in the melt conduits in a rheologically strong layer between 6 and 9 km depth. We conclude that the zone of fractures below Kolumbo is exploited by melts ascending from the mantle and filling the crustal melt reservoir. Together with the recurring seismic unrest, our study suggests that a future eruption is probable and monitoring of the Kolumbo volcanic system is highly advisable.
Climatology of Deep O+ Dropouts in the Night‐Time F‐Region in Solar Minimum Measured by a Langmuir Probe Onboard the International Space Station
Authors: Debchoudhury Shantanab , Barjatya Aroh , Minow Joseph I. , Coffey Victoria N. , Parker Linda N. 
Published: July 2022

AbstractThe Floating Potential Measurement Unit onboard the International Space Station includes a Wide sweeping Langmuir Probe that has been operating in the F‐region of the ionosphere at ∼400 km since 2006. While traditional Langmuir probe estimates include critical plasma parameters like electron density and temperature, we have also extracted the O+ percentage from the total ion constituents. This O+ composition data set from the recent minimum in the Solar Cycle 24 reveals orbits with dropouts in O+ to below 80% of the total background ion density at International Space Station orbital altitudes. The observed O+ percentages during these dropouts are much lower than the values predicted by the International Reference Ionosphere 2016 (IRI2016) empirical model. In this paper, we present the climatology of these O+ dropouts with their dependency on season, local time and geographical location. The results show that the lowered O+ percentages are more significant in the winter hemispheres and are routinely observed for orbits in the pre‐sunrise periods. The patterns in O+ dropouts can be explained in part from the lowering of the O+/H+ transition height during solar minimum along with patterns in neutral wind variation.
Quantifying the Impact of Lagged Hydrological Responses on the Effectiveness of Groundwater Conservation
Authors: Glose Thomas J. , Zipper Sam , Hyndman David W. , Kendall Anthony D. , Deines Jillian M. , Butler James J. 
Published: July 2022

AbstractMany irrigated agricultural areas seek to prolong the lifetime of their groundwater resources by reducing pumping. However, it is unclear how lagged responses, such as reduced groundwater recharge caused by more efficient irrigation, may impact the long‐term effectiveness of conservation initiatives. Here, we use a variably saturated, simplified surrogate groundwater model to: (a) analyze aquifer responses to pumping reductions, (b) quantify time lags between reductions and groundwater level responses, and (c) identify the physical controls on lagged responses. We explore a range of plausible model parameters for an area of the High Plains aquifer (USA) where stakeholder‐driven conservation has slowed groundwater depletion. We identify two types of lagged responses that reduce the long‐term effectiveness of groundwater conservation, recharge‐dominated and lateral‐flow‐dominated, with vertical hydraulic conductivity (KZ) the major controlling variable. When high KZ allows percolation to reach the aquifer, more efficient irrigation reduces groundwater recharge. By contrast, when low KZ impedes vertical flow, short term changes in recharge are negligible, but pumping reductions alter the lateral flow between the groundwater conservation area and the surrounding regions (lateral‐flow‐dominated response). For the modeled area, we found that a pumping reduction of 30% resulted in median usable lifetime extensions of 20 or 25 years, depending on the dominant lagged response mechanism (recharge‐ vs. lateral‐flow‐dominated). These estimates are far shorter than estimates that do not account for lagged responses. Results indicate that conservation‐based pumping reductions can extend aquifer lifetimes, but lagged responses can create a sizable difference between the initially perceived and actual long‐term effectiveness.
Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancer
Authors: Nicholson Hugh A. , Sawers Lynne , Clarke Rosemary G. , Hiom Kevin J. , Ferguson Michelle J. , Smith Gillian 
Published: July 2022

AbstractBackgroundOvarian cancer patients frequently develop chemotherapy resistance, limiting treatment options. We have previously shown that individuality in fibroblast growth factor 1 (FGF1) expression influences survival and chemotherapy response.MethodsWe used MTT assays to assess chemosensitivity to cisplatin and carboplatin following shRNA-mediated knockdown or heterologous over-expression of FGF1 (quantified by qRT-PCR and immunoblot analysis), and in combination with the FGFR inhibitors AZD4547 and SU5402, the ATM inhibitor KU55933 and DNA-PK inhibitor NU7026. Immunofluorescence microscopy was used to quantify the FGF1-dependent timecourse of replication protein A (RPA) and γH2AX foci formation.ResultsPharmacological inhibition of FGF signalling reversed drug resistance in immortalised cell lines and in primary cell lines from drug-resistant ovarian cancer patients, while FGF1 over-expression induced resistance. Ataxia telangiectasia mutated (ATM) phosphorylation, but not DNA adduct formation was FGF1 dependent, following cisplatin or carboplatin challenge. Combining platinum drugs with the ATM inhibitor KU55933, but not with the DNA-PK inhibitor NU7026 re-sensitised resistant cells. FGF1 expression influenced the timecourse of damage-induced RPA and γH2AX nuclear foci formation.ConclusionDrug resistance arises from FGF1-mediated differential activation of high-fidelity homologous recombination DNA damage repair. FGFR and ATM inhibitors reverse platinum drug resistance, highlighting novel combination chemotherapy approaches for future clinical trial evaluation.