bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of a PMMA tube on performances of a Vereos PET/CT system adapted for BSL-3 environment according to the NEMA NU2-2012 standard
Authors: Kahlaoui Nidhal , Naninck Thibaut , Le Grand Roger , Chapon Catherine 
Published: March 2022

Abstract
Introduction
A Vereos PET/CT device was adapted to be compatible with the experimentation in large animals within BSL-3 environment. The aim of this study was to investigate the impact of this modification on the performance according to NEMA NU2-2012 standard.

Methods
Spatial resolution, sensitivity, count rate performance, accuracies of corrections and image quality were assessed using the NEMA NU2-2012 standards before and after installation of a transparent poly-methyl methacrylate tube of 8 mm thickness, 680 mm diameter and 2800 mm long inside the tunnel of the system. In addition, CT performance tests were performed according to manufacturer standard procedure.

Results
Although the presence of the tube led to a slight decrease in sensitivity, performance measurements were in accordance with manufacturer preconisation ranges and comparable to previous performance published data.

Conclusion
Modifications of Vereos PET/CT system allowing its use in BSL-3 conditions did not affect significantly its performance according to NEMA NU2-2012 standard.

Key points
Question. Does a BSL-3 compatible modification alter Philips Vereos PET/CT performances according to NEMA NU2-2012 standards?
Pertinent findings. Our Vereos PET/CT system was modified by a wall separating BSL-1 and BSL-3 sides and an 8 mm thickness PMMA tube inserted into the bore of the camera in order to extend the BSL-3 containment along the bed movement. The performances of our modified system according to NEMA NU2-2012 standards were not significantly impacted by the modifications and were in accordance with the values prescribed by the manufacturer.
Implications for patients care. Our clinical PET/CT device was modified for human infectious diseases studies in Non-Human Primates. This unusual set up may then provide truly transposable data from preclinical studies into clinical application in infected patients.
Forensically important fly larvae on floating corpses in Malaysia: three case reports
Authors: Abdullah Syamsa Rizal , Shafie Mohamed Swarhib , Wahid Shahrom Abd 
Published: March 2022

AbstractBackgroundUnderstanding how environmental conditions can influence the insect distribution on corpses is essential to determine the postmortem interval. However, literatures related to forensically important flies in an aquatic environment were scarce. We report herewith a case series comprising three forensic cases related to floating corpses infested with fly larvae in Kuala Lumpur, Malaysia.Case presentationCase 1 involved the corpse of a 43-year old male found in the waterside of an abandoned mine. Case 2 was a 40-year-old male floating on a river stream, while case 3 was an 11-year-old boy who was found trapped in a monsoon drain after heavy rain. Numerous larvae of various stages, identified asChrysomya megacephala(Calliphoridae) species, were collected in all cases even though the number of larvae was relatively lower compared to those usually collected on corpses found on terrestrial areas. Besides, the larvae ofEristalisspp. (Syrphidae), which are known to be exclusively associated with water bodies, were found in two of the cases. The blowflyCh. rufifacies(Calliphoridae) larvae were collected only in case 3.ConclusionsThese findings show that bothCh. megacephalaandCh. rufifaciescan be found in the ecologically varied death scene habitats including aquatic areas. Meanwhile, the presence ofEristalisspp. can be used as an indicator of death location associated with an aquatic environment. The challenges and limitations of analyzing entomological evidence on bodies discovered in aquatic environments were also discussed.
Midline Brain Shift After Hemispheric Surgery: Natural History, Clinical Significance, and Association With Cerebrospinal Fluid Diversion
Authors: Phillips H. Westley , Maniquis Cassia A.B. , Chen Jia-Shu , Duby Shannon L. , Nagahama Yasunori , Bergeron David , Ibrahim George M. , Weil Alexander G. , Fallah Aria 
Published: March 2022

BACKGROUND:
Hemispherectomy and its modern variants are effective surgical treatments for medically intractable unihemispheric epilepsy. Although some complications such as posthemispherectomy hydrocephalus are well documented, midline brain shift (MLBS) after hemispheric surgery has only been described anecdotally and never formally studied.

OBJECTIVE:
To assess the natural history and clinical relevance of MLBS and determine whether cerebrospinal fluid (CSF) shunting of the ipsilateral surgical cavity exacerbates MLBS posthemispheric surgery.

METHODS:
A retrospective review of consecutive pediatric patients who underwent hemispheric surgery for intractable epilepsy and at least 6 months of follow-up at UCLA between 1994 and 2018 was performed. Patients were grouped by MLBS severity, shunt placement, valve type, and valve opening pressure (VOP). MLBS was evaluated using the paired samples t-test and analysis of covariance adjusting for follow-up time and baseline postoperative MLBS.

RESULTS:
Seventy patients were analyzed, of which 23 (33%) required CSF shunt placement in the ipsilateral surgical cavity for posthemispherectomy hydrocephalus. MLBS increased between first and last follow-up for nonshunted (5.3 ± 4.9-9.7 ± 6.6 mm, P < .001) and shunted (6.6 ± 3.5-16.3 ± 9.4 mm, P < .001) patients. MLBS progression was greater in shunted patients (P = .001). Shunts with higher VOPs did not increase MLBS relative to nonshunted patients (P = .834), whereas MLBS increased with lower VOPs (P = .001). Severe MLBS was associated with debilitating headaches (P = .048).

CONCLUSION:
Patients undergoing hemispheric surgery often develop postoperative MLBS, ie, exacerbated by CSF shunting of the ipsilateral surgical cavity, specifically when using lower VOP settings. MLBS exacerbation may be related to overshunting. Severe MLBS is associated with debilitating headaches.
Intracranial–Intracranial Bypass for Aneurysms: Quantitative Intraoperative Assessment of Flow Preservation
Authors: Koch Matthew J. , Stapleton Christopher J. , Charbel Fady T. , Russin Jonathan , Amin-Hanjani Sepideh 
Published: March 2022

BACKGROUND:
Intraoperative flow measurement has proven utility in extracranial–intracranial bypass, particularly in assessing the adequacy of donors by measurement of cut flow. The nature of intracranial–intracranial (IC–IC) bypass precludes cut flow measurement, but quantitative intraoperative flow measurements may evaluate augment assessment of the bypass.

OBJECTIVE:
To retrospectively evaluate flow measurements performed in IC–IC bypass to determine the adequacy of the constructs in preserving flow.

METHODS:
With institutional review board approval, we performed a retrospective review of our bypass database from 2001 to 2021 for aneurysms treated with IC–IC bypass and with intraoperative flow measurements. Patients' preoperative characteristics, bypass indications, prebypass and postbypass intraoperative flow measurements, and patient outcomes were recorded.

RESULTS:
Of 346 bypasses, 21 cases using 22 IC–IC bypasses were included. The median age was 55 years; 13 of 21 cases were ruptured aneurysms. Aneurysms involved posterior inferior cerebellar artery (n = 7), middle cerebral artery (n = 6), distal anterior cerebral artery (n = 5), and anterior communicating artery (n = 3). Six bypasses were end-to-side (ETS), 10 were side-to-side (STS), and 6 were excisional with reanastomosis (end-to-end, ETE). Intraoperatively, 21 of the bypasses were patent; the postbypass/prebypass flow index averaged 1.15 (±0.32): ETE (n = 6) 1.22 ± 0.34 and ETS/STS bypasses (n = 15) 1.11 ± 0.32. All intraoperatively patent bypasses were patent on postoperative angiography. One occluded on delayed angiography without clinical sequelae.

CONCLUSION:
Despite advances in endovascular therapy, IC–IC bypass remains essential to the treatment of large and fusiform aneurysms. We demonstrate quantitatively that IC–IC donors provide adequate direct (ETE) and redistributed (STS ETS) flow to the recipient territory. Flow measurement provides valuable information regarding the patency and adequacy of IC–IC bypass for flow preservation.
A Novel 5-Aminolevulinic Acid-Enabled Surgical Loupe System—A Consecutive Brain Tumor Series of 11 Cases
Authors: Zhang Xiaoran , Jaman Emade , Habib Ahmed , Ozpinar Alp , Andrews Edward , Amankulor Nduka M. , Zinn Pascal O. 
Published: March 2022

BACKGROUND:
The concept of maximally safe resection (MSR) has been shown to improve clinical outcomes in the treatment of high-grade gliomas (HGGs). To achieve MSR, surgical adjuncts such as functional imaging, neuronavigation, intraoperative mapping, ultrasound, and fluorescence-guided surgery are routinely used. 5-Aminolevulinic acid (5-ALA) is an oral agent that has been increasingly adopted in fluorescence-guided resection of HGG. In randomized clinical trials of 5-ALA, it has been shown to increase the extent of resection and progression-free survival in HGG. Current commercially available 5-ALA detection systems are all microscope-based and can sometimes be cumbersome to use.

OBJECTIVE:
To present our experience using a novel 5-ALA–enabled surgical loupe system.

METHODS:
5-ALA–enabled loupes were used in 11 consecutive patients with either suspected HGG on magnetic resonance imaging or recurrence of known lesions. Lesion appearance was examined under white light, 5-ALA loupes, and a 5-ALA microscope. Tumor specimens were checked for fluorescence and sent for pathologic examination.

RESULTS:
In our experience, a 5-ALA–enabled surgical loupe system offers excellent visualization of 5-ALA in patients with HGG. In 10 of 11 patients, fluorescent tissue was confirmed to be high-grade glioma by pathology. In 1 patient, tissue was not fluorescent, and final pathology was World Health Organization grade I meningioma.

CONCLUSION:
A 5-ALA–enabled surgical loupe system offers excellent intraoperative visualization of 5-ALA fluorescence in HGG and can be a viable surgical adjunct for achieving MSR of HGG.
Facile Synthesis of 1,7-Phenanthroline Derivatives and Evaluation of Their Properties as Hole-Blocking Materials in Organic Light-Emitting Diodes
Authors: Yamamoto Sachie , Yasuda Takeshi , Kanbara Takaki , Kuwabara Junpei 
Published: March 2022

Abstract
Phenanthroline derivatives are typical simple aza-polycyclic aromatic hydrocarbons that have been used as hole-blocking and electron-transporting materials in organic light-emitting diodes (OLEDs). In contrast to the widely used 1,10-phenanthroline derivatives, other isomers, including 1,7-phenanthrolines, have been explored less, partly due to the lack of effective and selective synthesis methods. This study demonstrates the facile synthesis of 1,7-phenanthroline derivatives bearing various substituents via a multicomponent reaction based on the aza-Diels-Alder reaction. By investigating the correlation between the substituents and their performance as hole-blocking materials in OLEDs, we gained insight into the molecular design of 1,7-phenanthroline derivatives for material applications.
Perceived risk of infection and death from COVID-19 among community members of low- and middle-income countries: A cross-sectional study
Authors: Gachabayov Mahir , Sharun Khan , Felsenreich Daniel M. , Nainu Firzan , Anwar Samsul , Yufika Amanda , Ophinni Youdiil , Yamada Chika , Fahriani Marhami , Husnah Milda , Raad Rawan , Khiri Namareg ME. , Abdalla Rashed YA. , Adam Rashed Y. , Ismaeil Mohajer IH. , Ismail Asma Y. , Kacem Wajdi , Teyeb Zeineb , Aloui Khaoula , Hafsi Montacer , Ferjani Manel , Dahman Nasrine Ben Hadj , Deeb Dalia A. , Emad Dina , Abbas Kirellos Said , Monib Fatma A. , Sami Farah S. , Ramanarayanan Subramaniam , Panchawagh Suhrud , Anandu Sunil , Haque Md Ariful , Ferreto Lirane ED. , Briones María FC. , Morales Rocío BI. , Lazcano-Díaz Sebastián , Aburto José TO. , Rojas Jorge ET. , Balogun Emmanuel O. , Kusuma Hendrix I. , Yeni Cut Meurah , Utami Niken Asri , Enitan Seyi S. , Yomi Akele R. , Durosinmi Abiodun , Adejumo Esther N. , Ezigbo Eyiuche D. , Babadi Elham , Kakemam Edris , Ullah Irfan , Malik Najma I. , Rosiello Francesco , Emran Talha B. , Imelda Eva , Wendt Guilherme W. , Arab-Zozani Morteza , Dhama Kuldeep , Mudatsir Mudatsir , Harapan Harapan 
Published: March 2022

Background: Risk perceptions of coronavirus disease 2019 (COVID-19) are considered important as they impact community health behaviors. The aim of this study was to determine the perceived risk of infection and death due to COVID-19 and to assess the factors associated with such risk perceptions among community members in low- and middle-income countries (LMICs) in Africa, Asia, and South America. Methods: An online cross-sectional study was conducted in 10 LMICs in Africa, Asia, and South America from February to May 2021. A questionnaire was utilized to assess the perceived risk of infection and death from COVID-19 and its plausible determinants. A logistic regression model was used to identify the factors associated with such risk perceptions. Results: A total of 1,646 responses were included in the analysis of the perceived risk of becoming infected and dying from COVID-19. Our data suggested that 36.4% of participants had a high perceived risk of COVID-19 infection, while only 22.4% had a perceived risk of dying from COVID-19. Being a woman, working in healthcare-related sectors, contracting pulmonary disease, knowing people in the immediate social environment who are or have been infected with COVID-19, as well as seeing or reading about individuals infected with COVID-19 on social media or TV were all associated with a higher perceived risk of becoming infected with COVID-19. In addition, being a woman, elderly, having heart disease and pulmonary disease, knowing people in the immediate social environment who are or have been infected with COVID-19, and seeing or reading about individuals infected with COVID-19 on social media or TV had a higher perceived risk of dying from COVID-19. Conclusions: The perceived risk of infection and death due to COVID-19 are relatively low among respondents; this suggests the need to conduct health campaigns to disseminate knowledge and information on the ongoing pandemic.
Can Positive Emotions Predict Consumer Satisfaction in Adverse Services?
Authors: Akthar Nahima , Nayak Dr. Smitha , Pai P Dr. Yogesh 
Published: March 2022

Background:Managing emotions during hospital visits is important to enhance patient satisfaction. The purpose of this paper is to explore the relationship between patients’ happiness and satisfaction through patients’ mood and perceived service quality at a healthcare setup.Methods:This study was conducted in a tertiary care hospital located in coastal Karnataka during the period from November to December 2021. Primary data was collected through a structured questionnaire from 227 respondents. “Statistical Package For The Social Sciences (SPSS) 27.0” and “SmartPLS 3.0” software was used for data analysis.Results:Hypotheses proposed in this study were examined by comparing the direct effect of patients’ happiness level on perceived service quality and the indirect effect of the level of patients’ happiness on patient satisfaction. The influence of all the exogenous latent variables namely, happiness, mood, perceived service quality, on the endogenous latent variable of patient satisfaction is estimated to be moderate (R2=62.5%)Conclusion:This study empowers hospital managers to recognize how patient satisfaction is dependent on patients’ happiness. In order to enhance patient satisfaction, the quality of care provided by health services, human resources, and infrastructure must be improved. As a result, the entire service encounter can be made enjoyable to the customers by reducing the distress caused by adverse services. Managers can utilize the outcomes of the study to develop marketing strategies to influence patients’ emotions in the healthcare setup by modifying the servicescape elements.
Digital taxation to promote frugal innovation in institutions of higher learning: a three-decade systematic literature review
Authors: Kwan Wei Ling , Dorasamy Magiswary , Bin Ahmad Abdul Aziz , Jayabalan Jayamalathi , Kumar Pradeep , Subermaniam Lingeswaran 
Published: March 2022

Background: In the era of the Fourth Industrial Revolution (IR 4.0), digital taxation emerged as a tool for accelerating the economic growth of a nation. While Industry 4.0 focuses on enabling real-time decision-making with sophisticated technology to enhance productivity, digital taxation can serve as an important tool for improving business sustainability. Institutions of higher learning (IHL), which aim to design an IR 4.0 educational ecosystem, can embrace digital taxation, as they face various challenges with different resources. The literature indicates that frugal innovation through digital taxation in institutions of higher learning, can solve emerging resource challenges. Method: We present a systematic review of studies on digital taxation to promote frugal innovation published in the past three decades (1991 to 2021). We obtained a total of 21 papers from a ‘digital taxation’ keyword search, 10 of which were related to digital taxation. However, the 10 papers were not related to frugal innovation. Result: We present two major findings. Firstly, research on digital taxation for frugal innovation is scant. Secondly, challenges exist in digital taxation implementation, which requires further attention. Conclusion: We conclude this review with a recommendation for the conceptual framework, to highlight potential research warranting the attention of the research community.
Alat Pembasmi Hama Otomatis Berbasis Solar Cell di Desa Pranggang, Kabupaten Kediri
Authors: Asfani Dimas Anton , Satriyadi Hernanda I Gusti Ngurah , Yulistya Negara I Made 
Published: March 2022

Pembangunan yang masif di Indonesia diikuti dengan semakin tingginya kebutuhan pangan untuk masyarakat mengakibatkan permintaan bahan pangan yang meningkat. Akan tetapi, beberapa tahun terakhir hasil pertanian di Indonesia mengalami penurunan. Hal itu disebabkan oleh meningkatnya kerusakan pada tanaman, salah satunya serangan hama yang meningkat. Namun, pengendalian yang masih kurang efektif mengakibatkan setiap tahun petani mengalami kerugian. Hama yang sering menyerang persawahan diantaranya adalah wereng, belalang, walang sangit, ulat, gangsir, dan tikus. Oleh sebab itu, pembasmian hama perlu dilakukan sebagai tindakan pengendalian pada tanaman. Solusi dari permasalahan ini adalah dengan cara membuat alat penangkap hama serangga dan pengusir tikus dengan sumber panel surya. Dengan menggunakan alat ini petani dapat mengurangi atau bahkan tidak memerlukan lagi untuk menggunakan pestisida yang dapat membahayakan kesehatan manusia dan lingkungan. Disamping itu, panel surya merupakan suatu alat yang dapat mengkonversi pancaran sinar matahari menjadi energi listrik. Teknologi panel surya merupakan salah stau teknologi yang praktis dan ramah lingkungan. Oleh karena itu, melalui skema pengabdian masyarakat yang dilakukan Laboratorium Tegangan Tinggi Departemen Teknik Elektro ITS turut membantu dalam pengendalian hama tikus dan serangga dalam meningkatkan produktivitas hasil panen dengan: (i) Pembuatan alat pengusir tikus dan serangga secara otomatis, (ii) Melaksanakan sosialisasi mengenai pengendalian hama dan penggunaan alat untuk meningkatkan produktivitas hasil panen, (iii) Melakukan konsultasi online untuk menjaga dan merawat alat dengan mitra.
Failure of Gan CRM Overcome by Successful Semont Manoeuvre in BPPV Post Head Trauma: A Case Study
Authors: Zainun Zuraida , Zuber Ahmadi Muhammad Munzir , Abdullah Jafri Malin , Bt Che Mat Amin Nur Syakirah 
Published: March 2022

Objective: Benign paroxysmal positional vertigo (BPPV) is one of common peripheral vestibular problem reported that head injury is one of common cause among young age. In current situation it only treated by medication or injection by medical officer and specialist. Medication is not an optimal treatment and it only symptomatic therapy and often need chronic prescriptions if not treated properly. There are an optimum specific manoeuvre offers curative therapy in majority of BPPV cases such as Epley’s manoeuvre, Gan Canal repositioning Manoeuvrer (CRM) and Semont manoeuvre. Semont manoeuvre is one of selected manoeuvre that recently done in posterior BBPV case if Epley’s and Gan CRM failed, but less practice among our clinician due to less exposure.
Case Studies: A 22 -year-old gentleman, complain of imbalance, difficulty in walking and vertigo for the past few days. He history of moderate traumatic brain injury (left parietooccipital Epidural Haemorrhage) and surgical intervention done last 5 days ago. He also complained of reduced hearing and on off left tinnitus over left side. No prominent psychological involvement reported.
Detail physical and balance assessment done using BAL EX Foam test Modified Dix Hallpike Test (DHT) done. During the left DHT there is rotatory up beating nystagmus then it proceeds with GRM three-time, 1 session on previous day and 2 session on the current day but it was failed. Then proceed with Semont manoeuvre by specialist in vestibular rehabilitation. After 10 minutes of manoeuvre, modified DHT done and show negative result found there is no nystagmus.
Consanguinity Among Refractive Error, Intraocular Pressure and Etiology of Glaucoma in Diabetics Among Wheatish Population
Authors: Ravuri Ravi Prasad 
Published: March 2022

The objective of this paper is to explore the connotation among refractive error, intraocular pressure (IOP), and primary open-angle glaucoma (POAG) among the Wheatish populace. Population-based studies give significant data with respect to the predominance and hazard factors which include refractive error for glaucoma. The connotation between myopia and glaucoma is robust at lower IOP levels and deteriorated slowly with increasing IOP. This study shows the relationship between IOP and glaucoma is solid at a lower mean value of 15 ±± 3.23 levels and debilitated progressively with expanding IOP of 17.59 ±± 3.33 for PACG, 18.85 ±± 1.20 for POAG, 18.59 ±± 2.52 for PIGM and 19.12 ±± 1.42 for OH among Wheatish population. The illustration of glaucoma in myopic eyes deteriorated with growing IOP and no association has been detected with IOP ≥≥35 mmHg.