bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weekly Isotretinoin Therapy (WIT) Study: A Potential Alternative for the Treatment of Moderate Acne Vulgaris
Authors: Karlin Samantha , Ritter Alexandra , Linkous Courtney , Wehlage Katherine , Wine Lee Lara 
Published: March 2022

Background: Treatment options for moderate acne remain limited.
Methods: We evaluated the efficacy of once-weekly dosed isotretinoin for moderate acne. Nineteen participants took isotretinoin dosed at 1-1.5 mg/kg/week for four months. Patient clinical improvement, quality of life, and adverse effects were measured at baseline and at monthly follow-up visits. Laboratory monitoring was performed at baseline and after two months.
Results: Ninety-five percent of patients (18/19) had improvement in their acne. The majority (68%) went from a baseline of moderate acne (score 3) to either clear (score 0) or almost clear (score 1) by the end of four months. There were no major lab abnormalities or adverse events. Eighty-nine percent of patients (17/19) reported improvement in their quality of life.
Conclusion: Once weekly isotretinoin may be an additional treatment option for patients with moderate acne.
New [4 + 2] Cycloadditions of in situ Generated Indolyl Enol Ethers and Their Anions with Dimethyl Acetylenedicarboxylate: A One-Pot Access to 4-Alkoxy-Substituted Carbazoles
Authors: Pindur Ulf , Rogge Martina 
Published: March 2022

The 3-indolyl(methyl)methoxycarbenium tetrafluoroborates 1a-d were deprotonated with NaH to furnish in situ the highly reactive 3-indolyl enol ethers 2a or their corresponding 3-indolyl enol ether anions 2b. Subsequent trapping of the enol ethers 2 with dimethyl acetylenedicarboxylate gave rise to 4-methoxy-functionalised carbazole derivatives in a HOMO(diene)-LUMO(dienophile)-controlled [4 + 2] cycloaddition. After variation of the 3-indolyl(alkoxy)carbenium tetrafluoroborates 1, Michael-type adducts and a ring-opened, biaryl product 6 were formed additionally.
Simulasi Berbasis MEH untuk Pemodelan Distribusi Potensial Listrik dan Medan Listrik pada Isolator Porselen 20 kV
Authors: NURHAKIM ASHADI AMIR , AR RASYID ROBBY IKHSAN , WALUYO WALUYO 
Published: March 2022

AbstrakIsolator adalah suatu perlengkapan yang cukup berarti dalam saluran udara tegangan menengah. Distribusi potensial serta medan listrik di sekitar isolator ialah wilayah yang masih mendapat pengaruh sifat kelistrikan dari suatu muatan. Riset ini mengulas simulasi distribusi potensial serta medan listrik pada isolator tegangan menengah berjenis porselen berbasis metode elemen hingga (MEH). Metode ini digunakan agar memudahkan dalam mengukur pendistribusian potensial listrik dan medan listrik pada isolator karena merupakan salah satu metode numerik yang lebih praktis untuk memecahkan masalah elektrostatik. Dari hasil simulasi 3D diperoleh pola distribusi potensial listrik selalu mengikuti kontur dari isolator sedangkan untuk distribusi medan listriknya mencapai nilai tertinggi sebesar 5,3 kV/cm. Sedangkan dari grafik distribusi medan listrik terlihat lebih jelas bahwa stress medan listrik yang besar terdapat pada daerah koneksi antara isolator dengan konduktor serta isolator dengan ground.Kata kunci: Isolator Porselen, Medan Listrik, Metoda Elemen Hingga (MEH), Potensial Listrik.AbstractAn insulator is a fairly significant piece of equipment in a medium-voltage overhead line. The distribution of potential and electric field around an insulator is an area that is still affected by the electrical properties of a charge. This research reviews the distribution of potential and electric field simulations on porcelain-type medium-voltage insulators based on the finite element method (FEM). This method is used to make it easier to measure the distribution of electric potential and electric field on an insulator because it is one of the more practical numerical methods for solving electrostatic problems. From the 3D simulation results, the distribution pattern of the electric potential always follows the contours of the insulator, while the electric field distribution reaches the highest value of 5.3 kV/cm. Meanwhile, from the electric field distribution charts, it is clearer that the large electric field stress is found in the area around the insulator with conductors and insulators with ground.Keywords: Porcelain Insulator, Electric Field, Finite Element Method (FEM), Electric Potential.
Metode Simple Additive Weigting dalam Penerapan Sistem Pendukung Keputusan Seleksi Santri Terbaik TPQ Yayasan Hubbu Ahmad Center
Authors: NULHAKIM LUKMAN , FAUSIYAH NANDA 
Published: March 2022

AbstrakProses seleksi santri terbaik pada Yayasan Hubbu Ahmad Center masih belum optimal. Banyaknya data nilai yang harus diolah dan seleksi hasil nilai tertinggi masih dilakukan dengan cara konvesional dengan memilih santri berdasarkan data yang ada kemudian dibuat kesimpulan bahwa santri tersebut mendapat predikat terbaik, tentu hal ini sangat kurang efektif dan tingkat ke akuratan yang dirasa kurang tepat. Dengan metode Simple Additive Weighting (SAW) proses seleksi dilakukan dengan urutan dan kriteria serta perhitungan yang tepat dan sesuai, sehingg sistem seleksi santri terbaik ini dengan tujuan membantu guru dalam menentukan santri terbaik dan tidak terjadi kesalahan. Dalam perancangan ini penulis menggunakan web base PHP sebagai aplikasi perhitungan seleksi santri terbaik dan MySQL sebagai database sistem. Kata kunci: Santri Terbaik, Mysql, PHP, SAWAbstractThe selection process for the best students at the Hubbu Ahmad Center Foundation is still not optimal. The amount of value data that must be processed and the selection of the highest results is still carried out in the conventional way by selecting students based on existing data and then a conclusion is made that these students get the best predicate, of course this is very less effective and the level of accuracy is felt to be less precise. With the Simple Addtive Weighting (SAW) method, the selection process is carried out with precise and appropriate sequences and criteria as well as calculations, the best student selection system with the aim of helping teachers determine the best students and there are no errors. In this design the author uses a web base PHP as the best student selection application and MySQL as a database system.Keywords: Best Santri, Mysql, PHP, SAW
Analisis Sistem Tanggap Darurat Tumpahan B3 Studi Kasus di Perusahaan Manufaktur
Authors: Pasha Mochamad Ulwan , Soemirat Juli , Deni M Candra Nugraha 
Published: March 2022

AbstrakIndustri semakin banyak menggunakan material dan proses yang tergolong berbahaya yang dikelompokan sebagai bahan berbahaya dan beracun (B3). Setiap proses produksi memiliki risiko terjadinya kecelakaan kerja yang diakibatkan oleh B3 hingga mengakibatkan keadaan darurat yang dapat merugikan secara kesehatan, material, dan finansial. PT X merupakan perusahaan yang bergerak di bidang manufaktur, dengan terdapat 5 proses produksi diantara nya: gudang penyimpanan barang produksi, konstruksi, nailing, assembling, dan finishing. Dalam tahap tersebut terdapat B3 seperti nikel, chromium, asam sulfat, dan solar yang digunakan. Oleh karena itu, perlu dilakukan evaluasi sistem tanggap darurat tumpahan B3 pada PT X, yang terdiri dari manajemen tanggap darurat, sarana dan prasarana tanggap darurat, dan pengelolaan B3 itu sendiri. Evaluasi dilakukan dengan membandingkan kondisi eksisting dengan peraturan diantaranya PermenLHK 74/2019, PermenLH 03/2008, dan beberapa National fire protection association (NFPA). Hasil evaluasi menunjukan nilai penerapan sistem tanggap darurat B3 di PT X sebesar 49,82% dikarenakan terdapat beberapa komponen yang belum tersedia dan beberapa komponen yang tidak sesuai standar. Oleh karena itu diperlukan suatu sistem tanggap darurat tumpahan B3 berupa rencana pengelolaan kedaruratan (RPK), mulai dari merencanakan tindakan pencegahan tumpahan, tindakan pada saat terjadi tumpahan, hingga pada pemulihan pasca tumpahan B3. Kata kunci: Industri, B3, Sistem Tanggap Darurat, rencana pengelolaan kedaruratanAbstractHazardous chemicals are substances that are classified known as hazardous substances. Production processes using such substances may carry a risk of work accidents caused by them resulting in emergencies that can be detrimental to health, and cause material, and financial losses. PT X is a manufacturing company, with 5 production processes i.e: warehouse storage of production, construction, nailing, assembling, and finishing, where hazardous materials such as nickel, chromium, sulfuric acid, and diesel are being used. Evaluation of hazardous materials spill emergency response system at PT X consisting of emergency response management, facilities and infrastructure, and proper management were conducted by comparing existing conditions with regulations including PermenLHK 74/2019, PermenLH 03/2008, and several National fire protection associations. The results showed that the implementation of these hazardous materials emergency response system at PT X only comply for 49.82% due to lack of some components and some were not in accordance with the exisiting standards. Hence the need for a comprehensive hazardous materials emergency response system in the form of an emergency management plan, starting from planning spill prevention measures, taking action in the event of a spillage to post hazardous materials spill recovery.Keywords: Industry, Hazardous Materials, Emergency Response, Emergency Management Plan
Pengendalian Sanitasi Makanan dengan Metode HACCP (Hazard Analysis Critical Control Point) di Asrama Haji Donohudan, Boyolali, Jawa Tengah
Authors: Laksana Muhammad Irfan Agung 
Published: March 2022

ABSTRAK Penyelenggaraan ibadah haji merupakan tugas negara. Pemerintah memiliki tanggung jawab dalam menjaga kondisi kesehatan jemaah, terutama keamanan pangan yang disediakan pihak katering. Penelitian ini bertujuan untuk menggunakan metode HACCP dalam pengendalian sanitasi makanan. Lokasi penelitian berada di Asrama Haji Donohudan, Boyolali, Jawa Tengah dam menggunakan data sekunder berupa indikator Coliform dan zat kimia pestisida, sianida, formalin, boraks, dan Rhodamin B. Critical Control Point (CCP) didapatkan pada 5 (lima) tahapan proses, yaitu pencucian peralatan masak dan makan, penyajian masakan, penerimaan pastel, kesehatan dan pendidikan higiene pekerja, dan penyiapan jus jambu. Dapat direkomendasikan perlunya tim HACCP yang bertanggungjawab atas sistem HACCP, tersedianya air yang memenuhi syarat kesehatan, disinfeksi peralatan masak dan makan, sertifikasi pekerja serta pendidikan higiene untuk semua manajemen dan pekerja. Kata kunci : Asrama haji, sanitasi makanan, HACCP, Critical Control Point ABSTRACTOrganizing pilgrimage is a state duty. The government has the responsibility to protect their health condition, especially the food safety provided by the caterer. The purpose of this study was to apply HACCP method in food sanitation. This research was conducted in the Donohudan Hajj Boarding House, Boyolali, Central Java and using secondary data consisted of Coliform indicator bacteria, pesticides, formalin, borax, cyanide, and rhodamine B. CCP (Critical Control Point) were obtained at 5 (five) stages of the process, namely washing of cooking and eating utensils, serving foods, receiving pastels, health and hygiene education for workers, and preparing guava juice. It can be recommended that there is a need for a HACCP team responsible for the HACCP system. It is also recommended to provide a safe drinking water supply, disinfection of all cooking and eating utensils, health certification of workers, and food sanitation education for all. Keywords: Hajj boarding house, food sanitation, HACCP, Critical Control Point
Pemilihan Sistem Pengelolaan Air Limbah Domestik di DAS Cisangkan
Authors: Wardhani Eka , Rosmeiliyana Rosmeiliyana 
Published: March 2022

AbstrakKota Cimahi merupakan wilayah penyumbang beban pencemaran yang besar terhadap Sungai Citarum. Terdapat 5 sungai di Kota Cimahi yang terindikasi tercemar berat diantaranya adalah Sungai Cisangkan. DAS Cisangkan ditempati oleh penduduk dengan kepadatan tinggi dan belum dilengkapi dengan sistem pengelolaan air limbah domestik. Penelitian ini bertujuan untuk mengetahui strategi pengendalian pencemaran air yang sesuai untuk Sungai Cisangkan. Pengendalian difokuskan kepada air limbah domestik sesuai dengan PerMenPUPR No. 4 Tahun 2017. Hasil penelitian menyebutkan bahwa mutu air Sungai Cisangkan masuk katagori cemar berat dengan parameter yang tidak memenuhi bakumutu diantaranya BOD, COD, TSS, Fecal coli dan Total Coli. DAS Cisangkan meliputi 10 kelurahan, berdasarkan hasil penapisan 7 diantaranya akan menerapkan sistem terpusat dan 3 kelurahan menerapkan sistem setempat. Pengelolaan secara terpusat akan menggunakan perpipaan yang akan menyalurkan ke instalasi pengolahan air limbah. Sistem setempat direncanakan dengan menggunakan tangki septik biofilter berkapasitas 200 kepala keluarga per unit.Kata kunci: Sungai Cisangkan, limbah, domestik, pengelolaanAbstractCimahi City is an area that contributes a large pollution load to the Citarum River. There are five rivers in Cimahi City that are indicated to be heavily polluted, including the Cisangkan River. The Cisangkan watershed is occupied by a high- density population and is not equipped with a domestic wastewater management system. This study aims to determine the appropriate water pollution control strategy for the Cisangkan River. Control is focused on domestic wastewater in accordance with the regulation of the Minister of Public Works and Public Housing No. 4/2017. The results stated that the quality of Cisangkan River water was categorized as heavily polluted with parameters that did not meet the quality standards, including BOD, COD, TSS, Fecal Coli and Total Coli. The Cisangkan watershed covers ten sub-districts; based on the results of the screening, 7 of them will implement a centralized system, and three villages will apply the local system. Centralized management will use piping that will supply the wastewater treatment plant. The local system is planned using a biofilter septic tank with a capacity of 200 households per unit.Keywords: Cisangkan River, domestic, wastewater, management
PSO based Hybrid PID-FLC Sugeno Control for Excitation System of Large Synchronous Motor
Authors: Duong Hung Quoc , Nguyen Quang Hong , Nguyen Duy Tien , Nguyen Lanh Van 
Published: March 2022

This paper proposes a hybrid control system integrating a PID controller and a fuzzy logic controller, using the particle swarm optimization (PSO) algorithm to optimize control parameters. The control object is an excitation system for a large synchronous motor, which is widely used in large power transmission systems. In practice, the change in load and excitation source can affect the operating mode of the motor. Therefore, a hybrid controller is designed to stabilize the power factor, resulting in better working performance. In the control algorithm, a PID controller is initially designed using PSO to optimize the control coefficients. The FLC-Sugeno control is then integrated with the PID, in which PSO is utilized to optimize membership functions. Numerical simulation results demonstrate the advantages of the proposed approach. Doi: 10.28991/ESJ-2022-06-02-01 Full Text: PDF
Positioning Climate Therapy Stays as a Health Tourism Product: An Evidence-Based Approach
Authors: Droli Maurizio , Bašan Lorena , Vassallo Fabio Giuseppe 
Published: March 2022

Background: The relationship between Length Of Stay (LOS) and Metres Above Sea Level (MASL) of Climate Therapy Stays (CTSs) and their therapeutic effectiveness and efficiency has been under-researched in the last four decades. As a consequence, the potentials of short-term and low-altitude CTSs remain unknown. Objectives: The purpose of this study is twofold. Firstly, it aims to ascertain whether LOS and MASL are related to the percentage change of Forced Expiratory Volume in 1 second (FEV1) and the percentage change of FEV1 Compound Daily Improvement Rate (FEV1 CDIR % Change). Secondly, it aims to provide an evidence-based positioning of CTSs by considering the same specific variables. Methods/Analysis: The study focuses on young people (age ˂18) who have asthma problems. The Resource-Based Theory, postulating the valuability of natural resources generating above-average benefits, has been adopted as a conceptual lens. Primary studies carried out in eastern and western European countries and separately reviewed have been considered jointly. Spearman’s rank correlation coefficient was used to determine the relationship between LOS and MASL of CTSs with FEV1Change (%) and FEV1Change CDIR (%) as indicators of health improvements. The descriptive statistics were implemented in calculating standardized and aggregated values. Findings: Negative and significant relationships have been highlighted between FEV1 Change (%) and MASL and between FEV1 Change CDIR % and LOS. In other words, subjects can achieve significant health improvements even by experiencing very short climate therapy stays at very low altitude mountain centres. Considering the FEV1Change (%) and the FEV1 Change CDIR (%) of climate stays by duration and elevation, the evidence-based knowledge platform has been established as a possible framework for developing an evidence-based marketing strategy for new health tourism products. Novelty/Improvement:Notwithstanding the need for further research, the metrics facilitating interdisciplinary, human health and economic studies have been devised. Further research on the effects of low altitude climate therapy stays could help define the healing potentials of macro and microclimatic conditions as potentially valuable ‘health devices’ for those suffering from respiratory diseases living in the COVID-19 era. Quantifying these effects through further studies, an evidence-based approach to formulating marketing strategies may be devised, useful both for supporting public health provision and policies, and for facilitating practitioners in health tourism interested in offering nature-based activities for their clients. Doi: 10.28991/ESJ-2022-06-02-04 Full Text: PDF
Reducing the New Inmates' Anxiety through Rational Emotive Behavior Therapy with Patronage Counseling Technique
Authors: Junaedi Farid , Hanurawan Fattah , Setiowati Arbin Janu , Ramli Muhammad 
Published: March 2022

Recurring cases of suicide, escapement, riots, and overcapacity have been observed in correctional institutions in Indonesia. Mental health issues are one of the causes of such a phenomenon. The emergence of this mental health issue may negatively impact inmates and cause disturbances in correctional institutions. Rational Emotive Behavior Therapy (REBT) focuses on transforming an irrational concept into a rational belief. This study aims to investigate the effects of REBT counseling with patronage technique on reducing anxiety levels. This new Patron-Client platform, equipped with the signification of gratitude and contentment, becomes a new form of proper counseling in a correctional institution. This study adopted the quasi-experiment before-after method with the Solomon four-group design. To garner the data, it involved four groups divided into two experimental and two control groups, consisting of 240 research population and 160 research subjects. ANOVA and T-test analysis were used to further analyze the obtained data. The findings show significantly different anxiety levels in the inmate groups before and after the treatment. Besides, no difference was observed in the inmates who did not receive the treatment. This study concludes that REBT counseling with patronage technique significantly decreases the inmates’ anxiety levels in the correctional institution. Doi: 10.28991/ESJ-2022-06-02-08 Full Text: PDF
Clinical and radiological outcome measures in patients after reconstruction of displaced acetabular fractures.
Authors: Adnan Latif Malik  , Muhammad Abdul Basit  , Muhammad Shakeel  , Muhammad Iqbal  , Muhammad Hanif  
Published: March 2022

Objective: To determine the clinical and radiological outcome parameters of surgical treatment of acetabular fractures in patients after reconstruction of displaced acetabular fractures. Study Design: Prospective study. Setting: Department of Orthopedics, Lahore General Hospital, Lahore. Period: January 2014 to December 2019. Material & Methods: A total of 27 cases of acetabular fractures operated with open reduction and internal fixation were included. Seven patients were lost to follow-up. The outcome measures were noted in 20 patients after three years follow-up. Modified Merle D'Aubigné and Postal score and Matta radiological scoring systems were utilized to note the outcomes. Results: There were 14 (70.0%) male and 6 (30.0%) female. Overall mean age was 35.5+8.4 years ranging between 25 to 65 years. Road traffic accidents were the most frequent mechanism of injury noted in 16 (80.0%) patients. The Kocher-Langenback approach was the most commonly adopted surgical approach done in 14 (70.0%) patients. The functional outcome according to Modified Merle D’Aubigné and Postal score was excellent in 9 (45%) patients and poor in 4 (20%). The radiological conclusion according to Matta’s radiological score was excellent in 8 (40%) patients and poor in 4 (20%). Four patients developed avascular necrosis of head of femur for which total hip replacement was done later. Conclusion: Complications were common and outcome was variable after reconstructing of displaced acetabular fractures.
Pemanfaatan Tepung Daun Eceng Gondok (Eichhornia crassipes) Difermentasi Menggunakan Cairan Rumen Sapi Terhadap Pertumbuhan Ikan Baung (Hemibagrus nemurus)
Authors: Kurniawan Rahmat , Suharman Indra , Adelina Adelina 
Published: March 2022

Eceng gondok mempunyai kandungan protein serta kandungan serat kasar yang cukup tinggi sehingga perlu dilakukan pengolahan sebelum digunakan sebagai bahan pakan. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan tepung daun eceng gondok terfermentasi terhadap pertumbuhan benih ikan baung. Penelitian ini dilaksanakan pada September-November 2019 yang bertempat di BBI, Sei Tibun, Kabupaten Kampar, Riau. Ikan uji yang digunakan dalam penelitian ini adalah benih ikan baung yang berukuran 5 cm dengan rata-rata bobot awal 1,26±1,17 g sebanyak 400 ekor. Benih ini diperoleh di Desa Lipat Kain Kampar, Riau. Penelitian ini menggunakan metode Rancangan Acak Lengkap satu faktor dengan 5 taraf perlakuan dan 3 kali ulangan. Perlakuan adalah pemberian pakan persentase subsitusi tepung kedelai dengan tepung daun eceng gondok terfermentasi yang berbeda yaitu (100:0%), (90:10%), (80:20%), (70:30%), dan (60:40%). Wadah yang digunakan pada penelitian ini adalah keramba yang berukuran 1x1x1m3 sebanyak 15 unit, dengan padat tebar sebanyak 20 ekor/wadah. Hasil penelitian menunjukkan bahwa penggunaan tepung daun eceng gondok terfermentasi sebagai bahan pakan ikan baung mampu mengurangi penggunaan tepung kedelai, ini terlihat dari pertambahan bobot rata-rata benih ikan baung setiap periodenya. Penggunaan tepung daun eceng gondok terfermentasi dalam pakan sebanyak 30% menghasilkan pertumbuhan benih ikan baung terbaik yang menghasilkan efisiensi pakan 46,64%, retensi protein 18,73%, laju pertumbuhan spesifik 3,85% dan kelulushidupan 99-100%.