bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using a socio-ecological framework to understand how 8–12-year-olds build and show digital resilience: A multi-perspective and multimethod qualitative study
Authors: Hammond Simon Patrick , Polizzi Gianfranco , Bartholomew Kimberley Jane 
Published: September 2022

AbstractEducationalists’, researchers’, and policy makers’ work on children’s digital resilience has marginalised the role of the broader context within which digital resilience is constituted, experienced and derived. We aimed to address this lacuna by exploring how pre-teen’s digital resilience operates as a dynamic socio-ecological process. Addressing this aim, we employed participatory methods and thematically analysed eight focus groups with children aged 8–12 years (n = 59) and 20 telephone interviews with parents/carers and teachers of 8–12-year-olds and internet safety experts to examine this issue. We used purposive sampling and collected data over three months (January-March 2020). Our analysis constructed a matrix of main themes, constituent, and cross-cutting sub-themes. By placing this within a socio-ecological framework, we illustrate how pre-teens’ digital resilience operates within and across differing four levels (individual, home, community and societal) and four domains (learning, recognising, managing, and recovery). The paper advances the literature by illustrating how children can be supported to build and show digital resilience within and across different levels and domains. It is argued that digital resilience should be re-conceptualised as a collective endeavour involving children at an individual level, parents/carers within home environments, youth workers, civil society, teachers, and schools at a community level, along with governments, policymakers, and the education system and internet corporations at a societal level. We conclude by providing practice and research recommendations guiding those supporting children to facilitate opportunities to thrive online.
Automated conduction velocity estimation based on isochronal activation of heart chambers
Authors: Santurri Michela , Bonga Jennifer , Schmid Maurizio , Cauti Filippo Maria , Solimene Francesco , Polselli Marco , Bura Mauro , Piccolo Francesco , Malacrida Maurizio , Pelargonio Gemma , Spera Francesco Raffaele , Bianchi Stefano , Rossi Pietro 
Published: September 2022

Abstract

Background
Spatial differences in conduction velocity (CV) are critical for cardiac arrhythmias induction. We propose a method for an automated CV calculation to identify areas of slower conduction during cardiac arrhythmias and sinus rhythm.

Methods
Color-coded representations of the isochronal activation map using data coming from the RHYTHMIA™ Mapping System were reproduced by applying a temporal isochronal window at 20 ms. Geodesic distances of the 3D mesh were calculated using an algorithm selecting the minimum distance pathway (MDP). The CV estimation was performed considering points on the boundary of two spatially and temporally adjacent isochrones. For each of the boundary points of a given isochrone, the nearest boundary point of the consecutive isochrone was chosen, the MDP was evaluated, and a map of CV was created. The proposed method has been applied to a population of 29 patients.

Results
In all cases of perimitral atrial flutter (16 pts out of 29 (55%)), areas with significantly low CV (< 30 cm/s) were found. Half of the cases present regions with low CV located in the anterior wall. No case with low CV at the so-called LA isthmus was observed. Right atrial maps during common atrial flutters showed low CV areas mainly located in the inferior inter-atrial septum. No areas of low CV were observed in subjects without a history of atrial arrhythmia while pts affected by paroxysmal AF showed areas with a limited extension of low CV.

Conclusions
The proposed software for automated CV estimation allows the identification of low CV areas, potentially helping electrophysiologists to plan the ablation strategy.
The Use of Drones in the Area of Minimizing Health Risk during the COVID-19 Epidemic
Authors: Król-Całkowska Esthera Justyna , Walczak Daniel 
Published: September 2022

AbstractDespite their general availability, drones are not currently widely used in emergency medicine, distribution of medication and other medical products, as well as in epidemiological emergencies, in which limiting interpersonal contact is crucial for minimizing the public health risk. Given the current epidemiological situation, it is pertinent to consider, whether implementing activities with the use of drones can significantly contribute to minimizing health risks, and whether such initiatives are acceptable in the light of applicable legal regulations. The main objective is supported by an analysis of the usefulness of applicable provisions, indicating the direction of possible changes in existing legal regulations. Additionally, the article aims to demonstrate the feasibility of drone use in activities related to combating epidemics, as well as to emphasize their practical importance. Reports on the commercial use of drones in the distribution of goods and services have also been used as material for comprehensive analysis. Simultaneously, the article also includes data on quantities of equipment available to healthcare units in Poland for saving life and health. The present work uses the method of analysis of applicable legal regulations, as a criterion for the usefulness of existing solutions in the area of improving the quality of medical services, including preventive measures and combating the effects of an epidemic.
Biological small-calibre tissue engineered blood vessels developed by electrospinning and in-body tissue architecture
Authors: Su Zhixiang , Xing Yuehao , Wang Fei , Xu Zeqin , Gu Yongquan 
Published: September 2022

AbstractThere are no suitable methods to develop the small-calibre tissue-engineered blood vessels (TEBVs) that can be widely used in the clinic. In this study, we developed a new method that combines electrospinning and in-body tissue architecture(iBTA) to develop small-calibre TEBVs. Electrospinning imparted mechanical properties to the TEBVs, and the iBTA imparted biological properties to the TEBVs. The hybrid fibres of PLCL (poly(L-lactic-co-ε-caprolactone) and PU (Polyurethane) were obtained by electrospinning, and the fibre scaffolds were then implanted subcutaneously in the abdominal area of the rabbit (as an in vivo bioreactor). The biotubes were harvested after four weeks. The mechanical properties of the biotubes were most similar to those of the native rabbit aorta. Biotubes and the PLCL/PU vascular scaffolds were implanted into the rabbit carotid artery. The biotube exhibited a better patency rate and certain remodelling ability in the rabbit model, which indicated the potential use of this hybridization method to develop small-calibre TEBVs.
Microwave-synthesized ZrO2/ZnO heterostructures: fast and high charge separation solar catalysts for dyes-waste degradation
Authors: Wahba Mohammed Ahmed , Yakout Saad Mabrouk 
Published: September 2022

AbstractIn 60 min, microwave-synthesized ZrO2/ZnO heterostructures exhibited high and fast sunlight photodegradation efficiencies for 50 ppm Congo red (CR) and 50 ppm methylene blue (MB) pollutants. ZrO2/ZnO heterostructures were characterized by XRD, SEM, EDX, FTIR, and diffuse reflectance (DR) techniques. The XRD analysis showed that these heterostructures have combined components of tetragonal ZrO2 and hexagonal ZnO phases. The SEM micrographs of all ZrO2/ZnO nanocomposites demonstrate the formation of nanospherical particles (major) and rod-like (minor) structures. The EDX spectra verified the presence of Zr, Zn and O elements with percentage ratios equivalent or close to that used during the experimental preparation. The FT-IR spectra showed the vibrational characteristic absorption modes of ZrO2 and ZnO bonds around 400–600 cm−1. Two band gap energies were estimated corresponding to ZrO2 (5.05–5.16 eV) and ZnO (3.1–3.16 eV) components. Remarkably, in presence of ZrO2/ZnO (30/70 at%) heterostructure, the free solar energy initiated photodegradation efficiencies of 87% and 98% for 50 ppm CR and 50 ppm MB dyes after 60 min, respectively, which indicates the fast and superior photocatalytic activity of microwave-synthesized ZrO2/ZnO heterostructure. As well, this composition reveals good reusability and stability for three photocatalytic cycles. This uppermost photodegradation performance can be assigned to the high separation of charge carriers, especially for the ZrO2/ZnO (30/70 at%) nanocomposite.
The cytoprotective role of GM1 ganglioside in Huntington disease cells
Authors: Hart Hannah S. , Valentin Madeline A. , Peters Stephanie Toering , Holler Susan W. , Wang Hongmin , Harmon Aaron F. , Holler Larry D. 
Published: September 2022

Abstract
Background
Huntington disease (HD) is a neurodegenerative disease where a genetic mutation leads to excessive polyglutamine (Q) repeats in the huntingtin protein. The polyglutamine repeats create toxic plaques when the protein is cleaved, leading to neuron death. The glycolipid GM1 ganglioside (GM1) has been shown to be neuroprotective in HD models, as it prevents the cleavage of the mutant huntingtin protein by phosphorylation of serine 13 and 16. Previous studies have tested GM1 in both adult-onset and juvenile-onset HD models, but this study set out to investigate whether GM1 mediated cytoprotection is influenced by the length of polyglutamine repeats.

Method and result
This study utilized cell culture to analyze the effect of GM1 on cell viability, directly comparing the response between cells with adult-onset HD and juvenile-onset HD. HEK293 cells expressing either wild-type huntingtin (Htt) (19Q) exon 1, adult-onset HD mutant Htt exon 1 (55Q), or Juvenile HD mutant Htt exon 1 (94Q) were assessed for cell viability using the WST-1 assay. Our results suggested moderate doses of GM1 increased cell viability for all cell lines when compared to untreated cells. When comparing HEK293 55Q and 94Q cells, there was no difference in cell viability within each dose of GM1.

Conclusion
These data suggest cellular responses to GM1 are independent of polyglutamine repeats in HD cells and provide insight on GM1’s application as a therapeutic agent for HD and other diseases.
Dispersion compensation: impact of integration of soliton transmission and cascaded apodized FBGs
Authors: Mustafa Fathy M. , Abdelhalim Mohamed M. , Aly Moustafa H. 
Published: September 2022

AbstractIn this paper, we present a tanh apodized FBG as a dispersion compensator in optical fiber communication systems. This grating is integrated as a hybrid system of four cascaded apodized FBGs with soliton transmission technique. This enhances the linewidth of the light source to get the most out of transmission per-channel bit rate of 9.687 Tbps at a temperature of 20 °C, a relative refractive index difference of 0.002, a Germania doping ratio of 0.2, and a signal wavelength of 1.65 µm.
Time trade-off health state utility values for depression: a systematic review and meta-analysis
Authors: Balázs Péter György , Erdősi Dalma , Zemplényi Antal , Brodszky Valentin 
Published: September 2022

Abstract
Purpose
This study aims to systematically review the literature on health utility in depression generated by time trade-off (TTO) method and to compare health state vignettes.

Methods
Systematic literature search was conducted following PRISMA guideline in 2020 November (updated in 2022 March) in Pubmed, Web of Science, PsycInfo, and Cochrane Database of Systematic Reviews. Random effect meta-analysis was conducted to pool vignette-based utility values of mild, moderate, and severe depression and to compare the preferences of depressed and nondepressed population.

Results
Overall, 264 records were found, 143 screened by title and abstract after removing duplicates, 18 assessed full text, and 14 original publications included. Majority of the studies (n = 9) used conventional TTO method, and most of the studies (n = 8) applied 10-year timeframe. Eight studies evaluated self-experienced health (own-current depression). Six studies assessed vignette-based health states of remitted, mild, moderate, and severe depression, half of them applied McSad measure based health description. Altogether, 61 different utility values have been cataloged, mean utility of self-experienced depression states (n = 33) ranged between 0.89 (current-own depression) and 0.24 (worst experienced depression). Pooled utility estimates for vignette-based mild, moderate, and severe depression was 0.75, 0.66 and 0.50, respectively. Meta-regression showed that severe depression (β = −0.16) and depressed sample populations (β =  −0.13) significantly decrease vignette-based utility scores.

Conclusion
Our review revealed extent heterogeneity both in TTO methodology and health state vignette development. Patient’s perception of depression health states was worse than healthy respondents.
The livelihood impacts of COVID-19 in urban South Africa: a view from below
Authors: Schotte Simone , Zizzamia Rocco 
Published: September 2022

AbstractThis paper investigates the impact of the COVID-19 pandemic and related policy measures on livelihoods in urban South Africa. Using qualitative research methods, we analyse two rounds of semi-structured phone interviews, conducted between June and September 2020 in the township of Khayelitsha, Cape Town. We contextualise these by presenting a snapshot of the nationwide dynamics using quantitative panel data. Our findings describe how the shock of the COVID-19 pandemic has deepened the economic vulnerability which preceded the crisis. Survivalist livelihood strategies were undermined by the economic disruption to the informal sector, while the co-variate nature of the shock rendered social networks and informal insurance mechanisms ineffective, causing households to liquidate savings, default on insurance payments, and deepen their reliance on government grants. In addition, the impact of the pandemic on schooling may deepen existing inequalities and constrain future upward mobility.
Monitoring of metal content in the tissues of wild boar (Sus scrofa) and its food safety aspect
Authors: Lénárt Zoltán , Bartha András , Abonyi-Tóth Zsolt , Lehel József 
Published: September 2022

Abstract
The study was performed on 10 female and 10 male wild boars (Sus scrofa) after shooting during the regular hunting season to investigate the concentration of metals in the muscle and fat tissue. The concentrations of essential and non-essential elements were determined (arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), lead (Pb), manganese (Mn), mercury (Hg), and zinc (Zn)) using inductively coupled plasma optical emission spectrometry. The concentrations of As, Hg, and Cd were below the limit of detection (As, Hg: < 0.5 mg/kg, Cd: < 0.05 mg/kg) in every tissue sample of both sexes. The lead was detected as 0.36 ± 0.16 mg/kg and 0.22 ± 0.06 mg/kg in the muscle of females and males, respectively, showing a significant difference between the sexes (p = 0.0184). The measured concentration of Cr was 0.14 ± 0.08 mg/kg and 0.13 ± 0.06 mg/kg, and that of copper was 1.22 ± 0.14 mg/kg and 1.06 ± 0.16 mg/kg in the muscle of females and males, respectively. The same tendency was observed in the case of copper content of fat tissues (female: 0.13 ± 0.10 mg/kg; male: 0.13 ± 0.04 mg/kg; p = 0.2707). Manganese concentration of muscle was 0.45 ± 0.30 mg/kg (female) and 1.36 ± 0.96 mg/kg (male), and that of fat tissue was 0.32 ± 0.22 mg/kg (female) and 0.74 ± 0.75 mg/kg (male). The Zn was detected as 56.75 ± 7.86 mg/kg and 1.83 ± 0.76 mg/kg in the muscle and fat of females and 52.12 ± 11.51 mg/kg and 1.94 ± 0.57 mg/kg in males, respectively. Based on data, the consumption of fat and muscle tissues of the wild boars tested can be food toxicologically objectionable, mainly due to the lead content, and thus pose a risk to frequent consumers of this type of game meat.
Critical events and pivotal factors as tools for analyzing the sustainability of online study programs
Authors: Suhonen Jarkko , Sutinen Erkki 
Published: September 2022

AbstractA critical aspect of designing and running online study programs is the identification of factors and elements that could potentially threaten the continuation of studies. In this study, we first identified a set of critical events that occurred in the running of a Finnish online doctoral study program over 16 years. Next, we analyzed the events using a four-pillar sustainability model, which consisted of the economic, social, environmental, and ethical pillars. We detected several contextually relevant and dynamic pivotal factors related to each of the pillars, which had effects on the sustainability of the program at the time of the critical events. The analysis revealed that positive pivotal factors in one sustainability pillar can be used to compensate for negative pivotal factors in the other pillars. Two aspects that were crucial for the sustainability of the online doctoral study program were the resilience and shared commitment of the community involved in its activities, which helped in overcoming any challenges encountered. Based on this study, we recommended that future research should design novel solutions that help online study programs to proactively identify potential critical events and related pivotal factors. Furthermore, studies should find creative approaches for constructively coping with critical events that have been identified.
Physics-Based Flow Stress Model for Alloy 718
Authors: Moretti Marie Anna , Lindgren Lars-Erik , Åkerström Paul 
Published: September 2022

AbstractA dislocation density-based model for alloy 718 in the annealed state is proposed in order to accurately describe the deformation behavior of this alloy for a wide range of thermo-mechanical loadings. The model accounts for numerous microstructural mechanisms, including strain hardening, grain size effect, dynamic strain aging (DSA), solid solution strengthening, as well as phonon and electron drag which affects dislocation movements at high strain rates. Two types of recovery mechanisms are also included: recovery due to dislocation glide and recovery associated with cross-slip of screw dislocations. The model is calibrated using experimentally determined stress–strain curves for both low and high strain rates in the order of 10–3to 103 s−1, and for temperatures in the range 20 °C to 800 °C. The stress–strain data computed with the model are in good agreement with the experimental data. The inclusion of DSA is found to be effective in the combination of temperatures and strain rates corresponding to experimental observations. The solid solution strengthening contribution increases with decreasing temperature and increasing strain rate. The drag effect in the model proves to be significant only for deformation at high strain rate (~ 103 s−1).
Performance evaluation of CNN and R-CNN based line by line analysis algorithms for fibre placement defect classification
Authors: Meister Sebastian , Wermes Mahdieu 
Published: September 2022

AbstractThe Automated Fibre Placement process is commonly used in aerospace for the manufacturing of structural components, but requires a subsequent inspection to meet the corresponding safety requirements. In order to improve this mostly manual inspection step, machine learning methods for the interpretation of 2D surface images are being increasingly utilised in research. Depending on the manufacturing process, a very long time can elapse between the appearance of a manufacturing defect and its recognition. Hence, in this paper Convolutional and Recurrent Neural Network techniques are presented that allow a line-by-line analysis of the incoming height profile scans of a Laser Line Scan Sensor as a 1D signal, which enables a direct reaction to a defect, even if only one or a few individual height profiles of the defect have been recorded. The combination of Convolutional and Recurrent Neural Network structures is particularly beneficial for this application. The investigations in this paper are especially interesting for developers of automated inspection systems in composite engineering.
Adult quality of life patterns and trajectories during the COVID-19 pandemic in Germany
Authors: Cohrdes Caroline , Wetzel Britta , Pryss Rüdiger , Baumeister Harald , Göbel Kristin 
Published: September 2022

AbstractEarly investigations of subjective well-being responses to the COVID-19 pandemic indicated average deterioration but also high variability related to vulnerability of population groups and pandemic phase. Thus, we aimed to gain new insights into the characteristics of certain groups and their differences in subjective well-being response patterns over time. First, we performed Latent Class Analyses with baseline survey data of 2,137 adults (mean age = 40.98, SD = 13.62) derived from the German CORONA HEALTH APP Study to identify subgroups showing similarity of a comprehensive set of 50 risk and protective factors. Next, we investigated the course of quality of life (QoL) as an indicator of subjective well-being grouped by the identified latent classes from July 2020 to July 2021 based on monthly and pandemic phase averaged follow-up survey data by means of Linear Mixed-Effects Regression Modeling. We identified 4 latent classes with distinct indicators and QoL trajectories (resilient, recovering, delayed, chronic) similar to previous evidence on responses to stressful life events. About 2 out of 5 people showed a resilient (i.e., relative stability) or recovering pattern (i.e., approaching pre-pandemic levels) over time. Absence of depressive symptoms, distress, needs or unhealthy behaviors and presence of adaptive coping, openness, good family climate and positive social experience were indicative of a resilient response pattern during the COVID-19 pandemic. The presented results add knowledge on how to adapt and enhance preparedness to future pandemic situations or similar societal crises by promoting adaptive coping, positive thinking and solidary strategies or timely low-threshold support offers.