bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing the effects of multimedia and face-to-face pain management education on pain intensity and pain catastrophizing among patients with chronic low back pain: A randomized clinical trial
Authors: Shaygan Maryam , Jaberi Azita , Firozian Roghayyeh , Yazdani Zahra 
Published: June 2022

Introduction
Previous studies into Low Back Pain (LBP) assessed the effects of physical interventions or face-to-face (FTF) education mostly in western cultures. The present study aimed to compare the effects of multimedia and FTF pain management education (PME) on pain intensity and pain catastrophizing among participants with chronic LBP.

Methods
This double-blind randomized controlled clinical trial was conducted on ninety participants with chronic LBP randomly allocated to either multimedia, FTF, or control groups. Participants in the multimedia group received PME through watching seven educational CDs at home and their counterparts in the FTF group received the same educations in seven weekly FTF educational sessions. Pain intensity (using a numerical rating scale) and pain catastrophizing (using the Pain Catastrophizing Scale) were assessed before, immediately after, and one month after the study intervention. The effects of the interventions were assessed using the repeated-measures multivariate analysis of variance (MANOVA). Effect size and minimal detectable change (MDC) were reported for both variables. The regression model used in the present study was Generalized Estimating Equations (GEE).

Findings
The findings of MANOVA showed the significant effects of time on pain intensity and pain catastrophizing (P<0.001). The Tukey’s test showed that before and immediately after the intervention, the mean scores of pain intensity and pain catastrophizing in the FTF and PME groups were significantly different from the control group (P<0.001 and P = 0.001, respectively). MDC did not show clinically significant changes in the mean score of pain intensity and GEE revealed significant difference among the groups.

Conclusion
The findings suggested that multimedia PME is as effective as FTF education in reducing pain intensity and pain catastrophizing among participants with LBP. Future studies into the effects of education on LBP are recommended to consider longitudinal designs, a reliable cutoff score for pain catastrophizing, and participants’ physical ability.

IRCT registration code
IRCT20180313039074N1.
Augmented risk of dementia in hypertrophic cardiomyopathy: A propensity score matching analysis using the nationwide cohort
Authors: Lee Heesun , Kim Hyung-Kwan , Kim Bongseong , Han Kyungdo , Park Jun-Bean , Hwang In-Chang , Yoon Yeonyee E. , Park Hyo Eun , Choi Su-Yeon , Kim Yong-Jin , Cho Goo-Yeong 
Published: June 2022

Background
Dementia is a big medical and socioeconomic problem on aging society, and cardiac diseases have already shown a significant contribution to developing dementia. However, the risk of dementia related to hypertrophic cardiomyopathy (HCM), the most common inherited cardiomyopathy, has never been evaluated.

Methods
In a large-scale longitudinal cohort using National Health Insurance database, 4,645 subjects with HCM aged ≥50 years between 2010 and 2016 were collected and matched with 13,935 controls, based on propensity scores (1:3). We investigated the incidence and risk of dementia, Alzheimer’s disease (AD), and vascular dementia (VaD) between groups.

Results
During follow-up (median 3.9 years after 1-year lag), incident dementia occurred in 739 subjects (4.0%): 78.2% for AD and 13.0% for VaD. The incidence of dementia, AD, and VaD were 23.0, 18.0, and 2.9/1,000 person-years, respectively, and was generally more prevalent in HCM. HCM group had a 50% increased risk of dementia, particularly AD, whereas there was no difference in the risk of VaD. The impact of HCM on AD (HR 1.52, 95% CI 1.26–1.84, p<0.001) was comparable with that of diabetes mellitus and smoking. Increased risk of AD in relation to HCM was consistent in various subgroups including younger healthier population.

Conclusions
This is the first to demonstrate the increased risk of dementia, mainly AD rather than VaD, in subjects with HCM. Early surveillance and active prevention for cognitive impairment could help for a better quality of life in an era that HCM is considered a chronic manageable disease with low mortality.
Association of Celiac Serology Normalization With the Risk of Hypothyroidism: A Cohort Study
Authors: Golan Maya Aharoni , Feldman Becca , Ollech Jacob E. , Hoshen Moshe , Shamir Raanan , Belfer Rachel-Gingold , Levi Zohar 
Published: June 2022

INTRODUCTION:
We evaluated whether persistent-positive celiac serology is associated with the risk of hypothyroidism.

METHODS:
We extracted a cohort of subjects aged 1–80 years with a positive IgA anti–tissue transglutaminase between January 1, 2008, and December 31, 2012, and a repeat anti–tissue transglutaminase test within 6–36 months from a large population-based electronic medical record database. Based on serology tests, we categorized the pediatric (age <21 years) and adult cohorts into normalized or persistent-positive serology groups. All subjects were followed up for incident diagnosis of hypothyroidism from the last serology date up to December 31, 2017. Hazard ratio (HR) along 95% confidence intervals (CIs) were prepared to evaluate the association of celiac serology group with a diagnosis of hypothyroidism, crude, and adjusted for age, sex, and diagnosis of type 1 diabetes mellitus.

RESULTS:
Among the pediatric cohort (n = 2,687), during a median follow-up of 64 months (interquartile range 48–80), 2.3% (16/681) of the persistent-positive serology group and 1.0% (20/2,006) of the normalized serology group developed hypothyroidism (HR 2.07 [95% CI 1.07–4.44], adjHR 1.77 [95% CI 0.91–3.46]). The rate among the pediatric cohort with an established diagnosis of celiac disease was 3.4% (10/486) vs 1.0% (5/481), HR 2.83 (0.96–8.32). In the adult cohort (n = 1,286), 4.5% (20/442) of the persistent-positive group and 3.9% (33/811) of the normalized serology group developed hypothyroidism (HR 1.13 [95% CI 0.65–1.97]).

DISCUSSION:
In this retrospective, age-stratified analysis, we report that persistent-positive serology may be associated with the risk of hypothyroidism among the pediatric population. Prospective cohorts are needed to validate our findings.
Step by Step Innovation without Mutually Exclusive Patenting: Implications for the Inverted U
Authors: Sedgley Norman 
Published: June 2022

Abstract
The step by step model of innovation is a benchmark model in research investigating the relationship between competition and innovation. The model assumes an industry can be in one of two states; leveled or unleveled. In an unleveled state the lagging firm is the only innovator. In a leveled state firms compete in a patent race. In this patent race successful innovation probabilities are mutually exclusive. This formulation provides mathematical tractability, but it has no other justification. I relax this assumption and use numerical simulation to demonstrate that allowing for non mutually exclusive success in innovation has important consequences for the inverted U relationship. The inverted U relationship is no longer a prediction of the model. In addition, the model predicts that patent measures will under count innovation from the leveled state, allowing for an inverted U relationship between competition and patenting under a narrow set of parameter restrictions. This theoretical exercise has important implications for understanding the current state of the empirical record on this topic.
Cross-reactivity in assays for prolactin and optimum screening policy for macroprolactinaemia
Authors: Smith Thomas P. , Kelly Sinead , Fahie-Wilson Michael N. 
Published: June 2022

Abstract

Objectives
Macroprolactin cross-reacts in immunoassays for prolactin causing apparent hyperprolactinaemia (macroprolactinaemia) and consequent misdiagnosis and mismanagement of patients.

Methods
We determined the prevalence of macroprolactinaemia using prolactin immunoassays with reported “high” (Tosoh) or “low” cross-reactivity (Roche) with macroprolactin. We additionally modelled the effects of increasing the screening threshold on workload and sensitivity in the detection of macroprolactinaemia.

Results
A review of routine requests for prolactin received in a 12 month period identified 670 sera with hyperprolactinaemia (Tosoh assay). Treatment with polyethylene glycol (PEG) precipitation demonstrated normal levels of monomeric prolactin in 165 sera (24.6%) indicating macroprolactinaemia. In the macroprolactinaemic cohort, total prolactin levels were lower with the Roche assay (473 ± 132 mU/L; mean ± SD) compared to the Tosoh assay (683 ± 217 mU/L), p < 0.005. The prevalence of macroprolactinaemia was also lower with the Roche assay (6.2%). The number of samples that required screening for macroprolactinaemia fell by 14% when Roche gender specific total prolactin reference limits were applied. Use of a higher screening threshold (700 mU/L) reduced the screening workload considerably (Roche by 45%, Tosoh by 37%) however, the sensitivity of detection of macroprolactinaemia decreased markedly (Roche 90%, Tosoh 59%).

Conclusions
Macroprolactin interferes in both Tosoh and Roche prolactin immunoassays. Use of an assay with a relatively low cross reactivity with macroprolactin, e.g. Roche, will lead to a modest reduction in the screening workload. Increasing the screening threshold above the upper limit of the assay reference interval will also reduce the screening workload but leads to disproportionate increases in the number of cases of macroprolactinaemia which are missed.
Co-operative actions in Chinese freestyle rap battles: a case ofIron Mic
Authors: Jia Mian 
Published: June 2022

AbstractRap battles are a growing phenomenon in China, but few studies have examined their interactional structure, especially from a multimodal perspective. In this paper, I conducted a microethnographic analysis of the sequential and simultaneous co-operation in Chinese rap battles from the national finals ofIron Mic. Results showed that in sequential co-operation, rappers accumulated the pre-existing end rhymes and created situated rhyming patterns in different rounds of battle performances, which helped them to outflow their opponents. Rappers also transformatively adapted lyrics and bodily movements from their opponents, demonstrating their ability to improvise and their superior lyricism over others. Moreover, battle emcees simultaneously used hand gestures to rebut their opponents’ accusations or show respect to the rap community. The study demonstrates that co-operative action is a viable theory to account for the interactional structure in rap battles and potentially other similar genres, highlighting the importance of a multimodal approach to social interactions.
Crosslinking of surface-sizing starch with cyclodextrin units enhances the performance of paper as essential oil carrier
Authors: Aguado Roberto , Ferreira A. Cláudia S. , Gramacho Sílvia , Murtinho Dina , Valente Artur J. M. 
Published: June 2022

Abstract
We present a feasible method to produce coated papers with long-lasting presence of natural active compounds. First, the composition of essential oils from Eucalyptus globulus was analyzed by gas chromatography-mass spectrometry (GC-MS), revealing high proportions of eucalyptol (73 %) and α-pinene (15 %) in the case of the leaves, and sesquiterpenoids like globulol and epiglobulol (55 %) for the wood essential oil. These compounds were incorporated onto paper sheets by conventional coating processes, using surface starch as binder. Nonetheless, the main source of novelty lies in the functionalization of starch with β-cyclodextrin by two-step esterification, resulting in enhanced binding capabilities. Release to air was evaluated by headspace-solid phase microextraction, using a divinylbenzene/Carboxen/polydimethylsiloxane fiber, whose adsorbates were analyzed by GC-MS. One week after coating a paper sheet with native starch and essential oil from E. globulus, terpineol, eucalyptol and pinene were below the limit of detection. The insertion of cyclodextrin moieties improved the protection of the most volatile active compounds from fast evaporation. Likewise, cyclodextrin units enhanced the preservation of antioxidant activity, but the weak scavenging potential of E. globulus essential oils was the limiting factor. In this sense, promising results were obtained by replacing said essential oil with hydroxytyrosol.
Mechanical properties and microstructure of nano-SiO2 and basalt-fiber-reinforced recycled aggregate concrete
Authors: Zheng Yuanxun , Zhuo Jingbo , Zhang Yamin , Zhang Peng 
Published: June 2022

Abstract
In this study, nano-SiO2 (NS) and basalt fiber (BF) were used to improve the quality of recycled aggregate concrete (RAC). The crushing value, water absorption, and apparent density of NS-modified recycled coarse aggregate (RA) were determined, and the effects of BF with different contents and lengths on the slump, compressive strength, splitting tensile strength, and flexural strength of RAC and BF-reinforced RAC containing NS-modified RA were analyzed. Finally, the filling effect of NS, the toughening and crack resistance mechanism of BF, and the micro-composite effect between NS and BF were analyzed based on scanning electron microscope (SEM) and energy-dispersive detector (EDS) measurement. The results show that the optimum modified concentration of NS solution is 2%, the content of BF is the main factor affecting the mechanical properties of concrete, and the optimum length and content of BF are 12 mm and 0.2%, respectively. For BF-reinforced RAC containing NS-modified RA, the 28 day compressive strength, splitting tensile strength, and flexural strength of RAC increase by 34.28, 40.55 and 54.5%, respectively. Based on SEM and EDS measuring, NS can react with Ca(OH)2 crystal to form flocculent C–S–H gel, which makes RAC compact and enhances the bonding properties of the interfacial transition zone (ITZ) between BF and the matrix.
Social robot – Jack of all trades?
Authors: Kühne Katharina , Jeglinski-Mende Melinda A. , Fischer Martin H. , Zhou Yuefang 
Published: June 2022

AbstractBackgroundSocial robots have been used in different roles, for example, in caregiving, companionship, and as a therapy tool, in recent years – with growing tendency. Although we still know little about factors that influence robots’ acceptance, studies have shown that robots are possible social companions for humans that help overcome loneliness, among other use cases. Especially in the given situation of forced social isolation, social companions are needed. Thissocial gapmight be filled by robots. We hypothesized that loneliness and the need to belong increase acceptance of social robots.MethodsOne hundred forty participants were asked to fill out an online survey on social robots and their acceptance in society. Questions on robots, demographical factors, and external factors (lockdown length) were asked and personal traits were also assessed.Results and interpretationAs expected, among other findings, loneliness of participants was positively linked to robots’ acceptance. Nevertheless, need to belong was not. We conclude from these results that social robots are a possiblesocial instrumentto overcome loneliness and that interaction with a robot cannot replace belonging to a social group because robots lack needs that humans or animals have. Also, personality traits and demographic factors were linked to robots’ acceptance. This means that, even though there are generalizable connections between robots’ acceptance and factors as loneliness, personal traits are at least of similar importance.DiscussionOur results provide important new insights into relationships between humans and robots and their limitations. Robots can ease our loneliness but are not seen as human. Future research needs to investigate factors that influence perception and acceptance of robots. Future lab-based studies with realistic human–robot interactions will deepen our insights of human understanding, perception, and acceptance of robots.
Construction-specific effects of phonological similarity avoidance
Authors: Czaplicki Bartłomiej 
Published: June 2022

AbstractPrevious research on similarity avoidance has focused on such phonological factors as featural similarity and adjacency. This paper additionally investigates the phonology-morphology interface and draws attention to morphological and lexical effects of similarity avoidance. Avoidance of identical or similar sounds may give rise to a variety of strategies, including periphrastic category formation, an unexpected allomorph of the stem or affix and a lexical gap. It is argued that, although similarity avoidance has a universal basis in language processing, the various strategies to implement it are construction specific. In particular, it is shown that one construction may exhibit a different scope of OCP effects than another, which entails that the constraints regulating OCP effects should be morphosyntactically indexed, in turn requiring reference to multiple cophonologies with distinct properties. A novel finding is that cophonologies may be delimited by the syntactic category of the base of category formation. Drawing on the insight of Construction Morphology, the analysis represents dissimilation as an interaction of construction-specific OCP constraints with schemas that include reference to the base. In order to derive the gradience of OCP effects, the relevant constraints are ranked on the basis of a similarity metric and formal complexity. The proposed constraint-based analysis aims to represent the construction-specific strategies for dealing with dissimilation and capture the observed gradience of the pressure.
Are Polish “DLA” and “KU” really synonymic purposive prepositions?
Authors: Kisiel Anna 
Published: June 2022

Abstract“Dla” and “ku” are widely considered to be multifunctional and polysemous prepositions sharing at least some semantic components. While agreeing with their wide functional spectrum, the author argues for them to be monosemous: “dla” brings a positive evaluation of something from a given perspective, whereas “ku” points to something happening when something else occurs. By analysing their connectivity and interchangeability, the author proves that, against lexicographic descriptions, the semantic structures of these prepositions are not identical and, in fact, do not share any semantic components.The semantic differences between the two prepositions make them prone to different types of contexts. “Dla” appears in purposive-intentional and benefactive contexts and collocates with various types of nouns, from gerunds to personal nouns. “Ku” prefers resultative sentences, in which it introduces a special stylistic tone of sobriety. Due to this, possible collocations of this preposition are very limited, and many are reported to be undergoing lexicalization.
Polgem – The recorded corpus of Polish geminate consonants
Authors: Rojczyk Arkadiusz , Porzuczek Andrzej 
Published: June 2022

AbstractThe report describes the recorded corpus of Polish geminate consonants. It is available at<http://www.prospeech.pl/kategorie/polgem>It contains 111 words with double consonant letters produced by 54 native speakers of Polish, yielding a total of 5994 recorded tokens. The corpus may be used for future research on the production of Polish geminates or for perception experiments with speakers of other geminating or non-geminating languages. The report provides information on the lexical structure of the corpus, recruited speakers and recording specification. It also contains basic statistics of the rate of observed degemination and rearticulation.
Platform Pricing Choice: Exclusive Deals or Uniform Prices
Authors: Shekhar Shiva 
Published: June 2022

Abstract
Platforms choose between offering exclusive deals or uniform prices to content providers in a setting where content providers can multi-home or single-home. We find that platforms offer exclusive deals for sufficiently large or sufficiently small values of standalone benefits. For sufficiently large or small standalone benefits, there are relatively large or small proportion of multi-homers to single-homers, exclusive deals allow to extract more efficiently from the content provider type that is relatively large in the market. Hence, it becomes more lucrative to employ exclusive deals regardless of the pricing strategy chosen by rival platform. We find that for standalone benefits being sufficiently small, exclusive deals equilibrium is also the industry profit enhancing outcome. On the other hand, when standalone benefits are large, exclusive pricing deals equilibrium leads to a prisoner’s dilemma type of outcome.
Of pharmakon: Hallucination in Amerindian perspectivism and speculative materialism
Authors: Šatkauskas Ignas 
Published: June 2022

Abstract

Aims
The paper discusses the concepts of hallucination and psychedelic experience in philosophical and anthropological contexts, where these terms bring in presuppositions regarding body and soul, nature and culture.

Method
The discussion of the concepts is presented in the context of the debate between Viveiros de Castro's Amerindian perspectivism and Meillassoux's speculative materialism, where in the former the concepts have undergone an anthropological epoché in addressing the problematic presuppositions of unreality and in the latter hallucination and related concepts appear in a canonical western sense as imitations of the real.

Results
This debate appears to be closely related to the project of naturalization of spirituality. The critique also extends to concepts such as psychedelic and entheogen. In respect to certain indigenous concepts like kepigari of the Matsigenka, observed in anthropology (Shepard, 2018; Danowski, Viveiros de Castro, 2021) and by revisiting Derrida's Plato's Pharmacy (1981) we suggest that the philosopheme of pharmakon suits the role of proximity with indigenous thought for comparative analyses and offers a perspective for psychedelic philosophy.

Conclusions
The suggestion of considering psychedelics as an existential medicine (Letheby, 2017) could be interpreted as offering a pharmakon with ambiguous, indeterminate possibilities which would emphasize its theoretical soundness.