bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comorbidity and Association of Posttraumatic Stress, Depression, Anxiety, and Somatic Complaints in COVID-19 Georgian Patients
at the Beginning of Pandemic
Authors: Sikharulidze Giorgi , Ratiani Levan , Sordia Mariam , Sikharulidze Elene , Khutsishvili Tinatin , Lejava Khatuna , Vermetten Eric 
Published: July 2022

Background:
The global pandemic which the world has been facing for the past two years has demonstrated the need to study the effects of this virus on mental health. Various studies showed that COVID-19 could be a threat to people's mental health and physical health, but the findings are still very limited. The purpose of the study was to fill an existing gap in corresponding literature by analysing Post Traumatic stress disorder (PTSD) symptoms, somatic complaints, depression and anxiety in COVID-19 patients and studying their comorbidity to determine the impact of the virus on the patients’ mental well-being.

Methods:
Patients diagnosed with COVID-19 took part in the study one month after their discharge from the hospital, accounting for 10% of all COVID-19 patients across Georgia during the research. PTSD Checklist (PCL-5) was used. Depression, somatic symptoms and anxiety were assessed using the Patient Health Questionnaire (PHQ).

Results:
The results have shown that COVID-19, as a traumatic event, presents an association with PTSD, depression, anxiety, and somatic complaints. A high prevalence of depression (38,6%), anxiety (34,9%), and somatic symptoms (47%) was displayed. The overall indirect effect of PTSD on somatic symptoms was significant through depression and anxiety: 0.16, 95% CI [0.08, 0.26]. According to the report, the indirect effect of PTSD on somatic symptoms of depression was 0.12, 95% CI [0.05, 0.20].

Conclusion:
The study presents important findings on the relations between COVID-19 and mental health. Somatic complaints, depression, anxiety and PTSD symptoms were prevalent in participants after a month since they had COVID-19. Correlations between somatic complaints, anxiety, depression and PTSD were also demonstrated. Even with various limitations to this study, it shows how COVID-19 could affect mental health and prepares the groundwork for further, more detailed research, which is necessary.
Features of CD4+ lymphocytes apoptosis in children with cryptosporidiosis
Authors: Starikova E. G. , Voronkova O. V. , Shubina N. I. , Starikov Yu. V. 
Published: July 2022

The aim of this study was to identify the features of CD4+ lymphocytes apoptosis in children with cryptosporidiosis. Feces for the detection of cryptosporidium and venous blood for the study of lymphocytes apoptosis were the material of the study. Mononuclear leukocytes were isolated from venous whole blood and cultured in a complete culture medium. Cells were incubated for 24 hours with inducers of the receptor (TNFα) and mitochondrial pathways of apoptosis (dexamethasone).Cryptosporidia have been found in 35% of acute intestinal infections in children. The number of lymphocytes with cytoflurimetric signs of apoptosis in the group of cryptosporidiosis-positive patients did not differ from that in patients without cryptosporidiosis (p=0.421). There were no intergroup differences in the number of CD4+ lymphocytes expressing the Fas receptor on their surface (p=0.462). In cultures incubated in the presence of dexamethasone, a decrease in the number of apoptotically altered CD4+ lymphocytes was registered only in the group of cryptosporidiosispositive patients (p=0.028).The study showed that in cryptosporidiosis, the sensitivity of CD4+ cells to the induction of the mitochondrial pathway of apoptosis changes in favor of slowing down this variant of cell death.
Outcome of COVID-19 in children: results of a 12-month follow-up
Authors: Chernova T. M. , Timchenko V. N. , Barakina E. V. , Zherebtsova A. A. , Gusarova N. S. , Khabarova Yu. S. , Bulygina V. V. , Shakhrai D. E. , Zhiglova A. V. , Ttsvetkova E. A. 
Published: July 2022

At present, there are isolated data on the clinical outcomes of COVID-19 in children, especially those who have experienced asymptomatic and mild forms of infection.Purpose: to analyze the nature and frequency of postCOVID symptoms in children during 12 months. after recovery.Materials and methods. The influence of demographic indicators, premorbid background, severity of infection and therapy in the acute period of the disease on the nature and frequency of symptoms in 1079 children who underwent laboratory-confirmed COVID-19 was studied. The results are presented with proportions (%) and calculation of 95% confidence interval according to Klopper-Pearson. Differences between groups were assessed using Pearson’s chi-square test. Differences in the groups were considered statistically significant at p < 0,05.Results. Health disorders in the post-COVID period were observed in 8,5% of children, more often in school-children aged 7–17 years (68.4%). Concomitant conditions were found in 38,0%. In most cases, the consequences were noted after a mild form of COVID-19 (77.2%), however, 13,0% of patients experienced an asymptomatic form of infection. Among convalescents, changes in the emotional sphere (2,1%), headache (1,8%), symptoms of asthenia (1,6%), cardiovascular (1,5%), dyspeptic (1,3%) were more often observed, cognitive (1,3%) disorders, neurotic disorders (1,0%), less often respiratory (0.8%), endocrine (0,4%) and visual (0,4%) systems, musculoskeletal system were involved (0.2%). Girls were significantly more likely to have vegetative disorders, while boys were significantly more likely to suffer from cognitive functions. Various antiviral therapy options (interferon-alpha, an oral antiviral drug, or a combination thereof) in the acute period of COVID-19 did not affect the possibility of post-COVID disorders, but there was a tendency to increase the frequency in children who did not receive etiotropic treatment (control group). In 14.1% of cases, post-COVID symptoms appeared late – after 5–10 months. after recovery. The course of rehabilitation therapy, including drug treatment and non-drug methods, made it possible to quickly restore the state of health of the observed children.Conclusion. In most cases, the violations were of a functional nature, due to a disorder of autonomic regulation. Rehabilitation and dispensary observation programs will allow timely restoration of the quality of life of children who have had COVID-19, including in a mild and asymptomatic form.
National Trends in the Achievement of Recommended Strategies for Stroke Prevention in U.S. Adults With Type 2 Diabetes, 2001–2018
Authors: Kuo Shihchen , Yang Chun-Ting , Herman William H. , Lisabeth Lynda D. , Ye Wen 
Published: July 2022

OBJECTIVE
To assess the national prevalence of and trends in achieving current guideline-recommended treatment goals and pharmacotherapies for primary and secondary prevention of stroke among U.S. adults with type 2 diabetes (T2D).

RESEARCH DESIGN AND METHODS
We performed serial cross-sectional analyses in 4,834 adults aged ≥45 years with T2D who participated in the 2001–2018 National Health and Nutrition Examination Survey. With stratification by stroke history, we estimated the proportion of adults with T2D who achieved current guideline-recommended strategies for stroke prevention. Preventive strategies for stroke were benchmarked against diabetes care and cardiovascular risk reduction guidelines.

RESULTS
Overall in 2001–2018, among those without stroke history, the proportion who achieved primary stroke prevention strategies ranged from 8.4% (95% CI 6.8–10.1) for aspirin/clopidogrel treatment in those with a higher cardiovascular disease risk to 80.5% (78.8–82.2) for nonsmoking. Among those with stroke history, the proportion who achieved secondary stroke prevention strategies ranged from 11.8% (8.7–14.8) for weight control to 80.0% (74.9–84.9) for glycemic control. From 2001 to 2018, among those without stroke history, there was a significant increase in statin therapy (Ptrend &lt; 0.0001), smoking abstinence (Ptrend = 0.01), and ACE inhibitor/angiotensin receptor blocker treatment for hypertension (Ptrend = 0.04) but a substantial decline in weight control (Ptrend &lt; 0.001). Among those with stroke history, only statin therapy (Ptrend = 0.01) increased significantly over time.

CONCLUSIONS
During 2001–2018, the achievement of some current guideline-recommended strategies for stroke prevention among U.S. adults with T2D improved but remains a challenge overall. Efforts are needed to improve implementation of strategies for stroke prevention in this population.
Membatik Jumputan untuk Meningkatkan Motorik Halus pada Masa Pandemi Covid 19 Melalui Home Visit
Authors: Tawulo Oshin Santi , Anhusadar Laode 
Published: July 2022

Penelitian ini bertujuan untuk mengetahui gambaran perkembangan motorik halus anak pada kelompok B di TK As-Salam. Penelitian ini menggunakan pendekatan tindakan kelas (PTK) dengan dua siklus model kemmis dan Mc taggart yang memiliki empat tahapan yakni perencanaan, tindakan, observasi, dan refleksi. setiap siklus dilakukan dengan tiga kali pertemuan.Tehnik pengumpulan data yang digunakan adalah observasi, dokumentasi dan penilaian. Hasil penelitian menunjukkan bahwa membatik jumputan dapat meningkatkan perekmbangan motorik halus anak kelas B di TK As-Salam Desa Labokeo Kecamatan Laeya Kabupaten Konawe Selatan. Perkembangan motorik halus anak mengalami perubahan yang sangat baik. Pada siklus 1 menunjukkan kemampuan motorik halus anak dominan berada pada kriteria ketuntasan 58,33% atau berada pada kategori cukup. Pada siklus 2 menunjukkan kemampuan motorik halus anak berada pada rentang penilaian berkembang sesuai harapan dengan kriteria ketuntasan sebanyak 75% atau berada dalam kategori baik kemampuan motorik halusnya pada indikator anak dapat membatik sesuai gagasannya indikator ketuntasannya 75%, anak dapat mengekspresikan diri melalui gerakan membatik kriteria ketuntasannya 75%, indikator anak dapat mengkoordinasikan mata dan tangan untuk melakukan gerakan yang rumit kriteria ketuntasannya 66,66%, indikator anak dapat menggunting sesuai pola kriteria ketuntasannya 75%.
Pengembangan Media Jari Pintar (JAPIN) Untuk Meningkatkan Kemampuan Berhitung Anak Usia 5-6 Tahun
Authors: Nurlidiah Nur , Husnul Bahri Husnul , Fatrica Syafri Fatrica 
Published: July 2022

Kurangnya variasi media yang mendukung proses belajar anak sesuai dengan karakteristik anak dalam perkembangan kognitif terkait kemampuan berhitung pada anak usia 5-6 tahun. Penelitian ini bertujuan untuk menghasilkan media jari pintar (JAPIN) yang sesuai dengan karakteristik kelompok B TK Islam integral DARUL FIKRI kota Bengkulu. Jenis penelitian yang digunakan adalah penelitian dan pengembangan (R&D) dengan menggunakan model ADDIE yang terdiri dari lima tahap yaitu Analisis, Perancangan, Pengembangan, Implementasi, dan Evaluasi. Namun karena peneliti menyesuaikan dengan kebutuhan yang ada, maka peneliti menggunakan uji coba produk skala kecil dengan diujicobakan kepada 8 orang anak.di TK Islam integral DARUL FIKRI kota Bengkulu dengan memperoleh hasil lembar kegiatan pre- test 44.92%, sedangkan lembar kegiatan post-test 85,15%. Dengan demikian terjadi peningkatan sebesar 44,23%, sehingga dapat dikatakan produk yang dikembangkan berupa media jari pintar (JAPIN) untuk meningkatkan kemampuan berhitung anak usia 5-6 tahun di TK Islam Integral DARUL FIKRI kota Bengkulu layak untuk digunakan. Kata Kunci : Media Jari Pintar (JAPIN), Kemampuan berhitung anak usia 5-6 tahun .
El castigo
Authors: Cano S Carlos Alberto 
Published: July 2022

Dentro del recorrido histórico que estamos haciendo de la cultura universal me llama la atención el castigo, pero tengo necesidad de advertir que la exigencia que me inspira a realizar este ensayo es más conceptual que histórica, pues el objetivo es examinar a grandes rasgos lo que ha significado el vocablo castigo en las diferentes épocas de la historia, es decir, tratar de establecer más su origen jurídico que el histórico, ya que con el primero se busca la fuente de un derecho, mientras con el estudio del origen histórico se indaga un hecho. Lo anterior no obsta para que logremos ubicar algunos hechos, cosa que es muy propia de la historia.
Epistemología y lenguaje en la obra de jürgen habermas
Authors: Salcedo Gutiérrez Hernando 
Published: July 2022

Jürgen Habermas es hoy el tipo de filósofo que no necesita presentación. Su extensa y conocidaobra, empezada a desarrollar en forma sistemática a mediados de la década del60, cuando apenas contaba con 35 años, ha sido reflejo del espíritu de la época. Polémico, analista de primera mano de lo que sucede y de lo que se dice en Alemania y el mundo, es el tipo de filósofo «que va a la plaza de mercado», es decir, que no concibe la filosoña como un metadiscurso propio de mandarines elegidos que encuentran la esencia de las cosas. Por el contrario, la filosoña es. para él la posibilidad de aclarar la acción cotidiana.
Jurisdicción judicial
Authors: Montaño Bedoya Julia Victoria 
Published: July 2022

Jurisdicción; del latín iurisdictio, iuris: jus (derecho) y dictio: (acto de decir) . En la Roma clásica, para la época de la orden judicial privada, la jurisdicción fue privada, ejercida por árbitros; desde la Roma postclásica, época del conocimiento extraordinario, ha sido pública, con resurgimiento de la jurisdicción privada en la figura del arbitraje.
El recurso de amparo y el tribunal constitucional español. Estudio sobre la tutela procesal cualificada de protección de los derechos fundamentales en el país ibérico
Authors: Agudelo Ramírez Martín 
Published: July 2022

El recurso de amparo en España es la principal garantía jurisdiccional para la protección dederechos definidos como fundamentales por la Constitución frente a actos concretos de las autoridades públicas y secundariamente de particulares. En este estudio se reflexiona sobre el referido mecanismo de tutela reforzada y privilegiada existente en el país europeo. El amparo constitucional es una garantía que sólo es posible considerar frente a aquellos derechos que en España se comprenden como fundamentales, no incluyendo numerosos derechos constitucionales o derechos humanos que no se ajustan a la referida categoría conceptual.El Tribunal Constitucional se constituye en la sede básica para la resolución del amparo considerado como un recurso extraordinario, excepcional y subsidiario de protección de derechos fundamentales. Aunque sus sentencias de amparo resuelven casos concretos, sus motivaciones o consideraciones contienen parámetros para la interpretación de los referidos derechos, vinculando los poderes públicos frente a un razonamiento que pasa a tener un valor erga omnes.En este ensayo se busca contribuir, en cuanto a derecho comparado, en el estudio de las vecindades y diferencias del amparo con la acción de tutela en el caso colombiano.
Evaluación de la sustitución del maíz por camote en la alimentación de gallinas ponedoras en un sistema de producción orgánico
Authors: Fogaça Giovana , Camargo Eliezer Ferreira , Da Silva Araújo Ednaldo 
Published: July 2022

El artículo tiene como objetivo evaluar la respuesta productiva de las aves cuando se alimentan con harina de camote en lugar de harina de maíz. El experimento se realizó en campo en dos propiedades rurales con certificación orgánica en la región de Londrina-PR. Se utilizaron 48 aves ponedoras de raza mixta roja. Se evaluaron los parámetros de producción, estándares de calidad externa e interna de los huevos durante 4 ciclos de 21 días. Para parámetros de producción como tasa de postura, conversión alimenticia y masa de huevo, hubo diferencia estadística (p<0.05) con un resultado superior para salvado de maíz. Para las variables de calidad externa del huevo no se encontraron diferencias estadísticas (p<0.05) entre tratamientos. Para el parámetro peso de cascarilla se encontró diferencia estadística con un resultado superior para el tratamiento con salvado de maíz. Para el análisis de calidad interna de huevos se encontró diferencia significativa para el salvado de maíz para las variables altura, peso y diámetro de yema. Para altura de albumen, color de yema, unidad Haugh, porcentaje de yema, porcentaje de albumen, índice de yema, pH de yema y albumen, no se encontró significación estadística. Al no diferir del tratamiento con maíz, los parámetros fueron satisfactorios para la producción de huevos con harina de camote. porcentaje de albúmina, índice de yema, pH de la yema y albúmina, no se encontró significancia estadística. Al no diferir del tratamiento con maíz, los parámetros fueron satisfactorios para la producción de huevos con harina de camote. porcentaje de albúmina, índice de yema, pH de la yema y albúmina, no se encontró significancia estadística. Al no diferir del tratamiento con maíz, los parámetros fueron satisfactorios para la producción de huevos con harina de camote.
Instituciones, democracia y subjetividad: los valores de la democracia en México
Authors: Rocha Romero Raul , García Feria Diana Laura 
Published: July 2022

Se plantea la problemática epistemológica, teórica y metodológica que existe en el abordaje de los valores y la consiguiente dificultad para investigar empíricamente los valores de la democracia. Se establece teóricamente la relación entre las instituciones políticas, la subjetividad de las personas y los valores de la democracia. Posteriormente se proporciona una definición psicosocial acerca de los valores. Se diseñó el Inventario de Valores de la Democracia (IVADE), considerando los siguientes indicadores: Igualdad, Libertad, Fraternidad, Pluralismo, Tolerancia, Participación, Legalidad, Responsabilidad, Justicia, Solidaridad. El inventario tiene 30 reactivos y es una escala tipo Likert de 5 puntos, y se aplicó a 186 ciudadanos mexicanos. Los resultados indican que los mexicanos reportan profesar en un nivel alto todos los valores de la democracia. Sin embargo, ello debe de contrastarse con el comportamiento democrático real de los mexicanos.
Factores Socioeconómicos Asociados a la Felicidad y Bienestar en Estudiantes Universitarios del Noroeste de México
Authors: Abril Valdez Elba , Cubillas Rodríguez Maria José , Domínguez Ibáñez Sandra Elvia 
Published: July 2022

El objetivo del estudio fue analizar, a partir del Índice de Felicidad (PHI), la relación entre percepción de bienestar y variables sociodemográficas familiares. Se realizó un estudio descriptivo, transversal con técnica de encuesta. Participaron 1106 estudiantes universitarios seleccionados, a través de un muestreo no probabilístico e intencional, de 8 universidades localizadas en la región norte, sur, centro y sierra del estado de Sonora. Para recabar la información se utilizó el Índice de Felicidad de Pemberton y un cuestionario que recabó datos sociodemográficos tales como sexo, tipo de familia, escolaridad de los padres, entre otros. Los resultados muestran que hombres y mujeres presentan un nivel de felicidad medio sin que las diferencias entre ambos sean significativas (p≥0.05). En cuanto a las variables sociodemográficas, el tipo de familia, la escolaridad del padre, la ocupación de la madre y el ingreso familiar fueron variables significativas en algunos elementos del PHI para percibir mayor felicidad o bienestar en su entorno.
НІМФИ КЛІЩІВ ВИДУ IXODES RICINUS, ЇХ ЖИВЛЕННЯ НА ТВАРИНАХ І ЛЮДИНІ ТА ЕПІДЕМІОЛОГІЧНА РОЛЬ
Authors: Podobivskiy S. S. , Fedoniuk L. Ya. , Rujytska О. Yu. 
Published: July 2022

Studies show that rodents are only one link in the food chain of the forest mite. J. Anderson [2] points out that in Europe this species attracts more than 300 species of warm-blooded animals and humans. The populational ecology and distribution of certain rodent species are related to the epidemiological situation among humans, mainly in the case of transmission of certain tick-borne pathogens, such as Borrelia burgdorferi sensu lato or tick-borne encephalitis virus (CE). Randolph S. E. [15] and Krebs C. J. [6] point to certain patterns in the biology of Ixodes mites and rodents. In particular, it has been noticed that in the spring the life cycle of mites is dominated by adults that feed on macro-mammals.
During 2017–2019, larvae, nymphs and adult mites of the Ixodes ricinus were collected from humans and animals and studied in a specialized laboratory of I. Horbachevsky Ternopil National Medical University. During 2017–2021, more than 1,900 specimens of mites were identified and studied. In this article, special attention is paid to the nymphs of this species. This is due to the fact that nymphs feed not only on animals, as in most other Ixodes mites, but also actively attack humans. The analysis of the ratio of nymphs and adults attacking people in the spring-summer and autumn periods of 2017–2019 has been carried out and the peculiarities of their epidemiological condition during the highest activity of ticks have been studied.
Certain patterns have been established, in particular, the frequency of their attacks on humans compared to adults correlates from 1.16 to 3.55 and is highest in April-May and then in September. The frequency of attacks of different stages of mites is obviously due to the life cycle of this type of mite and the ability to provide itself with food. It is possible that the high number of nymphs in April-May due to the inability to complete its life cycle in autumn, due to the lack of a host-host and the need to overwinter at the larval or nymph stage. Those individuals that manage to complete their life cycle in the fall, overwinter in the adult stage and in the spring they are already active in this life form. The lack of a host can be explained by the factor of a small number of murine rodents, due to which a large number of larvae and nymphs cannot continue their development.
Analysis of the epidemiological situation showed that in May, the infection with pathogens in nymphs ranges from 33 % to 48 % and in females - from 50 % to 65 %. In June, this indicator decreases significantly, and in September it rises again to 35–56 % in nymphs and 25–38 % in females.
SPATIAL THINKING OF STUDENTS OF HIGHER EDUCATION INSTITUTIONS AS AN INDICATOR OF THEIR INTELLECTUAL DEVELOPMENT
Authors: MAMUS HALYNA , URUSKUI ANDRII , HAVRYSHCHAK HAVRYSHCHAK 
Published: July 2022

The peculiarities of formation of spatial thinking in students of engineering and pedagogical specialties in the course of study of the graphic cycle disciplines have been substantiated. The definitions of “spatial thinking” and “spatial imagination” are clarified. The legitimacy of spatial thinking as an independent mental process, which is associated with the analysis of spatial features and the relationship between elements of real objects (or their graphic images) and application of these features in resolution of design problems by students of engineering specialties of higher education is mentioned.
The content and basic operational units of spatial thinking in undergraduates during their study of graphic disciplines have been described. The dependence of the level of development of spatial thinking of students on the type of spatial images operating in Descriptive Geometry, drawing, engineering and computer graphics lessons has been specified. There has been offered the typology of students of engineering and pedagogical specialties of pedagogical high school, depending on their level of spatial thinking development and ability to explicit spatial transformations. The initial level of spatial thinking development of the students of the first year of study before the study of the cycle of graphic disciplines in higher education institutions has been also analyzed. The prospects of resolution of the issue of increasing the level of spatial thinking in undergraduates as an indicator of their intellectual development have been outlined in the study.