bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Report: Fatal Outcome for a Preterm Newborn With Meningitis Caused by Extended-Spectrum β-Lactamase-Producing Escherichia coli Sequence Type 1193
Authors: Oldendorff Frida , Linnér Agnes , Finder Mikael , Eisenlauer Peter , Kjellberg Malin , Giske Christian G. , Nordberg Viveka 
Published: April 2022

IntroductionIn this case report, we describe an extended-spectrum beta-lactamase (ESBL) – Escherichia coli (E. coli) strain of sequence type (ST) 1193, a novel, virulent, multidrug-resistant (MDR) clone with a rapid global spread. ST 1193 has been more commonly associated with invasive disease than other ESBL-E. coli STs. To our knowledge, this is the first known case in Sweden where a newborn died of an ESBL-E. coli ST 1193 meningitis. We emphasize that the clinical knowledge about the properties of certain MDR-clones should be increased.Case ReportA moderately preterm boy was born after preterm prolonged rupture of membranes. The mother had an ESBL-E. coli urinary tract infection during pregnancy. At 36 h of age he developed signs of infection and was given first-line therapy for early onset sepsis. Thereafter he developed seizures. The treatment was changed to cover suspected meningitis. Culture showed growth of the same ESBL- E. coli ST 1193 strain in the child’s blood and cerebrospinal fluid, as well as in the mother’s urine. Antibiotics were adapted. His condition deteriorated and he developed fulminant septic shock with treatment-resistant seizures. The boy passed away at 3 days of age.ConclusionThis case highlights the risk of delay in diagnosis when a marking for carriage of MDR-bacteria is falsely removed from a medical record of a pregnant women. Further, it demonstrates that ESBL-E. coli ST 1193 infection in neonates can be fatal. Thus, studies regarding virulence factors of ESBL-E. coli infections in pregnant women and their children are needed to understand the association between this infection and severe invasive disease in newborn children.
Choice of Antimicrobials in Surgical Prophylaxis - Overuse and Surgical Site Infection Outcomes from a Tertiary-Level Care Hospital
Authors: Vippadapu Prasanna , Gillani Syed Wasif , Thomas Dixon , Ahmed Fiaz , Gulam Shabaz Mohiuddin , Mahmood Rana Kamran , Menon Vineetha , Abdi Semira , Rathore Hassaan Anwer 
Published: April 2022

Background: This study was aimed to describe the choice of Surgical Antimicrobial Prophylaxis at a tertiary-level care hospital in United Arab Emirates. It also associated the choice between two leading antimicrobials for the SAP to the site of surgery.Methods: A descriptive drug use evaluation was performed retrospectively to study choices of antimicrobials in surgical antibiotic prophylaxis. An analytical cross-sectional study design was used to develop a hypothesis regarding the choice of ceftriaxone. Data were collected from the medical records of Hospital from July 2020 to December 2020. Results were presented in numbers and percentages.Results: SAP data were collected from 199 patients, of which 159 were clean or clean-contaminated. Dirty surgeries (18) needed a higher level of antimicrobials as there were infections to be treated. For other surgeries with no infection, overuse of antimicrobials was found regarding the choice of antimicrobials. Surgical antibiotic Prophylaxis was administered within the recommended time prior to surgeries. Ceftriaxone was preferred over cefuroxime in all types of surgeries based on the timing of Surgical Antibiotic Prophylaxis, wound classification, and the surgical site. A statistically significant association for choice of ceftriaxone over cefuroxime was found regarding surgical sites (p-value &lt;0.05). About 99% of the patients were prescribed discharge antimicrobials when 158 (80%) surgeries were clean or clean-contaminated.Conclusion: Overuse of antimicrobials was found in surgical antimicrobial prophylaxis. Ceftriaxone was preferred more than cefuroxime in all types of surgeries. No surgical site infections were reported. A follow-up comparative study is recommended to decrease antimicrobial use without increasing risk of surgical site infection.
Poorer Well-Being in Children With Misophonia: Evidence From the Sussex Misophonia Scale for Adolescents
Authors: Rinaldi Louisa J. , Smees Rebecca , Ward Jamie , Simner Julia 
Published: April 2022

ObjectiveMisophonia is an unusually strong aversion to a specific class of sounds – most often human bodily sounds such as chewing, crunching, or breathing. A number of studies have emerged in the last 10 years examining misophonia in adults, but little is known about the impact of the condition in children. Here we set out to investigate the well-being profile of children with misophonia, while also presenting the first validated misophonia questionnaire for children.Materials and MethodsWe screened 142 children (10–14 years; Mean 11.72 SD 1.12; 65 female, 77 male) using our novel diagnostic [the Sussex Misophonia Scale for Adolescents (SMS-Adolescent)]. This allowed us to identify a group of children already manifesting misophonia at that age – the first population-sampled cohort of child misophonics examined to date. Children and their parents also completed measures of well-being (for convergent validation of our SMS-Adolescent) and creative self-construct (for discriminant validation).ResultsData show that children with misophonia have significantly elevated levels of anxiety and obsessive compulsive traits. Additionally children with misophonia have significantly poorer life-satisfaction, and health-related quality of life. As predicted, they show no differences in creative self-construct.ConclusionTogether our data suggest the first evidence in population sampling of poorer life outcomes for children with misophonia, and provide preliminary convergent and discriminant validation for our novel misophonia instrument. Our data suggest a need for greater recognition and therapeutic outlets for adolescents with misophonia.
Relationship Between Psychological Impacts of COVID-19 and Loneliness in Patients With Dementia: A Cross-Sectional Study From Iran
Authors: Mohammadian Fatemeh , Rezaee Mahya , Kalantar Arash , Mohebbi Niayesh , Motamed Mahtab 
Published: April 2022

ObjectivesAlthough the COVID-19 pandemic has affected people all around the world, the elderly is at a higher risk of suffering from its consequences. One of the serious concerns is developing loneliness and post-traumatic stress symptoms, which may contribute to cognitive decline at older ages. This study aimed to examine the psychological responses and loneliness in elderly patients diagnosed with dementia.MethodsTwenty-one patients diagnosed with dementia, with ages older than 40, and 19 caregivers were enrolled in the study. The patients have undergone a comprehensive neuropsychiatric interview and were assessed with De Jong Gierveld Scale for loneliness and Impact of Event Scale—Revised (IES-R). The severity of dementia was assessed by Functional Assessment Staging Tool (FAST Scale) and the Montreal Cognitive Assessment (MoCA).ResultsNo significant difference was seen in patients and caregivers in the IES-R and loneliness scales. A higher level of avoidance and social and total loneliness were seen in higher FAST levels (p-value: 0.046). There was a negatively significant correlation between MoCA score and avoidance. Hyperarousal was significantly correlated with emotional loneliness in patients.ConclusionWe found a direct relationship between cognitive decline and the psychological impacts of COVID-19. Our results highlight the need for more comprehensive studies to further investigate the influence of the pandemic on the worsening of cognitive impairment and loneliness in patients with dementia.
How Two-Child Policy Affects China's Energy Consumption: The Mediating Role of Lifestyle
Authors: Chen Fengzhang , Wang Wei , Wang Yanfei , Wu Yongqiu 
Published: April 2022

BackgroundExisting literature believed that the birth control policy affects energy consumption through the change in population size, but ignored the changes in people's lifestyle. This may mislead the government's policy-making about population and energy consumption.MethodThis article proposed a Population-Lifestyle-Energy (PLE) model to provide new insights into how birth control policy affects energy consumption if the changes in people's lifestyle are considered. The ProFamy software is used to forecast the changes in demographic characteristics. The methods of regression analysis and Input-Output Analysis are used to predict the impacts of lifestyle changes on energy consumption.ResultsWe find that China's two-child policy will result in the total energy consumption increase by 16.2% in 2050, far outpacing the population increase of 9.3% when considering the indirect effect of lifestyle changes. This is significantly different from the optimistic wisdom in the existing literature. We also find the non-linear relationships between fertility rate and energy consumption.ConclusionIgnoring lifestyle changes will lead to an underestimation of energy consumption. Contrary to conventional optimistic wisdom, we believe that the two-child policy will make it difficult for China to meet promised energy conservation goals.
Transparency of COVID-19-Related Research in Dental Journals
Authors: Sofi-Mahmudi Ahmad , Raittio Eero 
Published: April 2022

ObjectiveWe aimed to assess the adherence to transparency practices (data availability, code availability, statements of protocol registration and conflicts of interest and funding disclosures) and FAIRness (Findable, Accessible, Interoperable, and Reusable) of shared data from open access COVID-19-related articles published in dental journals available from the Europe PubMed Central (PMC) database.MethodsWe searched and exported all COVID-19-related open-access articles from PubMed-indexed dental journals available in the Europe PMC database in 2020 and 2021. We detected transparency indicators with a validated and automated tool developed to extract the indicators from the downloaded articles. Basic journal- and article-related information was retrieved from the PMC database. Then, from those which had shared data, we assessed their accordance with FAIR data principles using the F-UJI online tool (f-uji.net).ResultsOf 650 available articles published in 59 dental journals, 74% provided conflicts of interest disclosure and 40% funding disclosure and 4% were preregistered. One study shared raw data (0.15%) and no study shared code. Transparent practices were more common in articles published in journals with higher impact factors, and in 2020 than in 2021. Adherence to the FAIR principles in the only paper that shared data was moderate.ConclusionWhile the majority of the papers had a COI disclosure, the prevalence of the other transparency practices was far from the acceptable level. A much stronger commitment to open science practices, particularly to preregistration, data and code sharing, is needed from all stakeholders.
Diagnostic Ideas and Management Strategies for Thrombocytopenia of Unknown Causes in Pregnancy
Authors: Li Jie , Gao Yue-Hua , Su Jing , Zhang Lu , Sun Yan , Li Zeng-Yan 
Published: April 2022

ObjectiveTo summarize the clinical characteristics and treatment options together with the maternal and neonatal prognoses in women with different degrees of thrombocytopenia of unknown causes during pregnancy.Materials and MethodsOne hundred twenty-nine cases meeting the inclusion and exclusion criteria were retrospectively analyzed. Patients were divided into group A (50*109/L) and group B (50*109/L to 100*109/L) according to the lowest level of platelet count during pregnancy. Patients were divided into those found to have thrombocytopenia in the relatively early, middle, and late stages according to the detection period of maternal thrombocytopenia during pregnancy.ResultsThere were 72 cases in group A, and 57 cases in group B. There existed statistically significant differences in terms of the proportion of primipara, the proportion with a history of thrombocytopenia, and the median length of pregnancy between the two groups (p &lt; 0.05). The proportion of patients with severe thrombocytopenia as an indication for cesarean delivery was higher in group A than in group B (p &lt; 0.05). More cases were detected at the relatively early stages of pregnancy in group A than in group B (p &lt; 0.05). There was no difference in neonatal hemorrhage and events of thrombocytopenia between the two groups.ConclusionPatients with platelet counts below 50*109/L were mostly primipara with a history of thrombocytopenia, most often detected at a relatively early stage of pregnancy, and continued pregnancy might lead to aggravation of the disease. Combination therapy was required for patients with platelet counts below 30*109/L to maintain the platelet counts within a safe range. Cesarean delivery was selected to terminate the pregnancies, and platelet counts should be raised above 50*109/L before surgery. Close monitoring was required for those with platelet counts above 30*109/L. There was no direct correlation between the maternal and neonatal platelet counts.
Recurrence and Prognostic Value of Circulating Tumor Cells in Resectable Pancreatic Head Cancer: A Single Center Retrospective Study
Authors: Zhang Qiao , Xia Feng , Sun Qiang , Cao Wenjing , Mo Ali , He Weiming , Chen Jiazhen , Zhang Weiqiao , Chen Weiqiang 
Published: April 2022

Background and AimTo investigate the effect of preoperative circulation tumor cells (CTCs) on postoperative recurrence and overall survival prognosis of pancreatic head cancer after pancreaticoduodenectomy (PD).MethodsFrom March 2014 to January 2018, 73 patients with pancreatic head cancer underwent radical resection (R0) in Zhongshan People's Hospital. CTCs in peripheral blood of patients with pancreatic head cancer were detected by “Cyttel” method before PD. Seventy-three patients were divided into positive and negative groups according to the positive criteria. To explore the relationship between the clinical data of CTCs and disease-free survival (DFS) and overall survival (OS). Cox proportional hazards model was used to analyzing the risk factors affecting the postoperative recurrence and the survival prognosis of patients.Results41 patients (56.2%) were in the CTC-positive group. Preoperative CTCs were correlated with tumor vascular invasion, CA199 level and postoperative liver metastasis (P &lt; 0.05). Preoperative CTC-positive, lymph node metastasis, vascular invasion, and nerve invasion were independent risk factors for DFS (P &lt; 0.05). Preoperative CTC-positive, tumor diameter &gt; 2 cm and vascular invasion were independent risk factors for OS of patients (P &lt; 0.05).ConclusionThe detection of CTCs before PD is an important factor affecting the DFS and OS of pancreatic head cancer, which is significant in guiding clinical work.
Novel Hypertrophic Cardiomyopathy Diagnosis Index Using Deep Features and Local Directional Pattern Techniques
Authors: Gudigar Anjan , Raghavendra U. , Samanth Jyothi , Dharmik Chinmay , Gangavarapu Mokshagna Rohit , Nayak Krishnananda , Ciaccio Edward J. , Tan Ru-San , Molinari Filippo , Acharya U. Rajendra 
Published: April 2022

Hypertrophic cardiomyopathy (HCM) is a genetic disorder that exhibits a wide spectrum of clinical presentations, including sudden death. Early diagnosis and intervention may avert the latter. Left ventricular hypertrophy on heart imaging is an important diagnostic criterion for HCM, and the most common imaging modality is heart ultrasound (US). The US is operator-dependent, and its interpretation is subject to human error and variability. We proposed an automated computer-aided diagnostic tool to discriminate HCM from healthy subjects on US images. We used a local directional pattern and the ResNet-50 pretrained network to classify heart US images acquired from 62 known HCM patients and 101 healthy subjects. Deep features were ranked using Student’s t-test, and the most significant feature (SigFea) was identified. An integrated index derived from the simulation was defined as 100·log10(SigFea/2) in each subject, and a diagnostic threshold value was empirically calculated as the mean of the minimum and maximum integrated indices among HCM and healthy subjects, respectively. An integrated index above a threshold of 0.5 separated HCM from healthy subjects with 100% accuracy in our test dataset.
Vieillir et mourir en institution d’hébergement collectif
Authors: Brigand Jean-Marie , Gres Sylvaine , Raphaël Freddy , Grimm Marie-Antoinette , Herberich-Marx Geneviève 
Published: April 2022

Altern und sterben im altersheim .
Alter ist eine Erfahrung die ein Jeder in seinem tiefsten sein erlebt, aber das sich auch in einem Kulturellen Kodex einfiigt und somit Sinn bekommt. Es ist in ein Nestz von sozialen Regeln eingetragen die eine bestimmte handlung-sart hervorrugen. Was von Claudine Herzlich von Kran heit behauptet wird, ist auch vom Alter wahr : Alter bezieht sich auf sich selbst aber auch auf die Gesellschaft und gemäss der Gesellschaft. Alt werden, ein totales Gesellschaftlisches Phänomen.
Alt werden ist für den Soziologen ein komplexes Phänomen das sich zu dem physiologischen sowie zu dem gesellschaftlichen bezieht. Die gesellschaftliche Struktur prägt ihre Marke auf das Individuum, nicht nur durch Erziehung der Bedürfnisse und der Korperstatigkeiten, aber auch durch die Stazung und dem Gebahren die sie den Alten aufzwingt.
Die neue Kunst gut ait zu werden indem man die voile Aktivität des körpers und des Geistens beibehaltet, will die objektive Vorbedingungen einer solchen Möglichkeit nicht kennen. So der Bericht Laroque : (4) : Jeder wird das Alter so erleben wie er es sich vorbereitet hat. Diese Begrenzung ist wichtig. Dazu die Frage : ist es eigentlich übersehbar dass dieses Willensimperativ besondere Verwandstchaften mit «der Rücktrittspraxix di man bei den neuen Mittelklassen, Arbeitsnehmen wie Stammpersonal, Ingenieure, Teckniker», beobachten kann, besitzt ?
«Alter nicht hinter die Gitter !» : Dieses mobilmachende Schlagwort mit seinen anarchistischen Akzenten überdeckt sicherlich physiologische, psycholo-gische und soziale Schwierigkeiten, die viele alte Leute, die allein ihre Existenz übemehmen, erfahren müssen. Es tut jedoch Kund, wohl etwas übermässig, des «grossen Verschliesens» des Wahnsinns, Wahmehmung der gegenwartigen westlichen Gesellschaft, also einer unüberschreitbaren Grenze zu ihrem Projekt.
Diese Gesellschaft kümmert sich eher um ein Zustand als um Existenzen. Mehr als die ökonomische Hindernisse die sehr schwer wiegen seitens dem Pflegepersonal um die altéré Person zu einem Maximum von Autonomie zu bringen ist es klar geworden dass die totale übemahme der letzteren, zu dem Verlust ihrer sozialen Identitat führen.
Ein neues Integrationsprojekt ersetzt die traditionelle Hilfs und Absonderungs Politik und will damit die Behauptung an den Tag bringen dass es zugleich möglich und vorteilhaft für den einzehlen, sowie für die Gesellschaft sein Raum, seine soziale Einfügung sowie eine gewisse Autonomie der alteren Bevölkerung, zur verlaügem, mit Hilfe von Einsetzung einer Reihe leichter Hilfseinrichtungen dessen Koordination besonders Wirksam werden kann. Jedoch, in diesen Zeiten der Krise wurde dieses Programm durch Struktur und Organisationschranken gehemmt.
Unsere Arbeit untersuchte die Vorbedingungen und die Grenzen der Heimpflege, und auch der Wartungslisten um in die kollektive Strukturen eintreten zu konnen, sowie die der Beziehung der Alteren Leuten Zeit und Raum in der kollektiven Stiftung.
Convocation de la mémoire en milieu ouvrier
Authors: Raphaël Freddy , Herberich-Marx Geneviève 
Published: April 2022

Gedächtnisberufung in Arbeiterkreisen

Wie es Maurice Halbwachs darlegt (Die soziale Ramen der Erinnerung, Paris 1925), ist die Sittenvorstellung hauptsächlich ein Gedenken das auf einem kollektiven Inhalt beruht. «Doch, so meint er, allein diejenige Erinnerungen und allein derjenige Inhalt verbleiben von ihnen, die die Gesellschaft zur jedem Zeitalter wieder herstellen kann, indem sie ihre aktuellen Rahmen als Objekt einer Untersuchungsarbeit aufnimmt».
Die Einfügunsschwierigkeit in einer ständig wechselnder Welt, das Machtlosigkeitsgefühl gegenüber von komplexen, brutal und zutiefst sich veränderden Lagen, kann dazu beiführen zitterig in einer verschönerten Vergangheit Zuflucht zu suchen, oder, im Gegenteil, Die Modernität mit dem Lichterglanz das Neuen, des Konfortes, ja sogar des spielerichen Schöpfungsgefühls, zu beschmücken. Die verwickelte Beziehung der Handwerkerischen Vergangheitsvorstellung mit der technischen Kultur sowie ihre Gliederung zu dem personalem Erlebnisgedenken, zu gewerkschaflich und politisch geprägten Erinnerungen, soll das Ziel dieser vorliegenden Untersuchung sein, mit besonderer Aufmerksamkeit für Berichtsstrategie sowie für die in Korper eingeprägten Spuren. Dazu sind wir auch Zeugen interessanter Versuche Kandwerkererlebnisse wieder auf zu erwecken, ohne jedoch sehnsuchstvoller Heraufbeschwörung einer Verschonerten Vergangheit zu huldigen, und die somit die Herausfordeungen der Gegenwart besser zum Verständniss bringen.
Droit et forêt : les chemins de l’identité
Authors: Bloch-Raymond Anny , Richez Jean-Claude 
Published: April 2022

Gesetze und Waldbestand : Auf dem Wege zu einer Identität.

Der Waldbestand wurde im Elsass zum Objekt gleichsam einer Aneignung auf dem Gebiet sowohl des Gesetzes, der Wirtschaft, als auch der Gesellschaft und der Symbolik.
Er hat eine echte Sozialstruktur aufgebaut, die fortbesteht, während die historischen Emergenz-Bedingungen verloren gingen. Diese Sozialstruktur gilt nun als Identifikationsfaktor, der spezifischen Vorschriften unterliegt. Jeder Eingriff in dieses System bewirkt eine soziale Deregulierung. Demnach tendiert diese Struktur zu einer Erstar-rung und folglich zu einer Entwertung der Identitäten, deren Träger sie ist. Ihre Zukunft hängt nun davon ab, ob sie fähig ist, sich zu verändern, sich an neuen sozialen Anforderungen anzupassen. Ihre Erneuerung fordert eine nicht nur lokale sondern nationale Anerkennung, in einer Umwelt, die mehr als je die Normalisierung der Aneignungsmethoden dieser «forstlichen Umwelt» begünstigt.
Localité et liens sociaux résidentiels : La réalisation expérimentale d’habitat social à Lutterbach
Authors: Jonas Emmy , Jonas Stéphane 
Published: April 2022

Ein experimentaler Entwurf sozialer Wohnungen in Lutterbach.
Das REX-Lutterbach Experiment ist eines der ministeriellen experimentalen Bauprogramme fiir Sozialwohnungen und Stadtplanungen genannt «Banlieue 89». Dieses Beispiel betrifft den Bau von 24 Sozialwohnungen auf der Lage einer ehemaligen berühmten Brauerei in diesem Vorort von Mulhouse, im Rahmen eines Projekts fur eine neu-Entwicklung des Stadtzentrums.
Die Soziologe/Beobachter dieses Experiments berichten hier über Aspekte des Entwurf-Prozeβes, über die Verhältniβen zwischen den betreffenden Part-nern, und über die Rolle des soziologischen Beobachters und Forschers. Unter andern psychosoziologischen Tests haben sie die Methodik der Kennzeichen Konstellation benutzr, im Laufe der aktiven Mitwirkung der zukünftigen Einwohnern zum Entwurf der Architektur.
Passeport périmé pour une mémoire collective et une identité locale
Authors: Dubinsky-Titz Monique 
Published: April 2022

A passport no longer valid for a collective memory and local identity.
Passport is a frontier, an ephemeral one which is sanctioned by an administrative and military device on the crest of the Vosges, a separation between Alsace and Lorraine, and between 1870 and 1918.
This «modern» frontier followed after a moving (blurred) frontier which was challenged and contested during centuries always situated at the boarders of the property belonging to Dukes, Kings and the central authority of the Republic.
These frontiers left traces which are still visible 70 years after their disappearance.
These physical traces and the traces in the memories, whether conscious or unconscious, are voted in the survival of original cultural characteristics of the local population, which continue to be a reference for them.