bluuebunny/crossref_metadata_2025_split huggingface dataset:
Collision with Gondwana or with Baltica? Ordovician magmatic arc volcanism in the Marmarosh Massif (Eastern Carpathians, Ukraine)
Authors: Gawęda Aleksandra , Szopa Krzysztof , Golonka Jan , Chew David , Stepanyuk Leonid , Belskyy Volodymir , Waśkowska Anna , Siliauskas Laurynas , Drakou Foteini 
Published: July 2022

AbstractThe pre-Alpine Marmarosh Massif is a tectonically complex unit of the crystalline basement within the Eastern Outer Carpathians. In the eastern (Ukrainian) segment of this massif, two units have been identified—the Bilyi Potok Nappe and the Dilove Nappe. Petrological investigations coupled with zircon U–Pb dating were performed on metavolcanic rocks (porphyroids) and their phyllite host rocks, sampled from three locations within the Dilove Nappe. The geochemical characteristics of the meta-rhyodacite porphyroids revealed a volcanic arc affinity of the protolith, with U–Pb zircon ages of 452.8 ± 1.5 Ma and 461.5 ± 1.6 Ma and zircon saturation temperatures in the range of 823–892 °C. The phyllite host rocks (meta-tuff) yield a U–Pb zircon maximum estimate for the eruption age at 584.7 ± 2.9 Ma. Peak amphibolite-facies metamorphism (M1) was estimated at the pressure of 600–900 MPa with a temperature range of 560–600 °C. Retrogression (M2), possibly related to Alpine nappe stacking and shearing, is assumed to have taken place at 200–250 MPa and 384–222 °C. The volcanic arc is interpreted as an early Caledonian arc that was subsequently accreted to the margin of Baltica during the closure of the easternmost Tornquist Ocean rather than Cenerian (early Paleozoic) orogenic events on the margin of East Gondwana.
Proteomic comparison between physiological degeneration and needle puncture model of disc generation disease
Authors: He Shuangjun , Zhou Xinfeng , Yang Guotao , Zhou Zhangzhe , Zhang Yijian , Shao Xiaofeng , Liang Ting , Lv Nanning , Chen Jianhong , Qian Zhonglai 
Published: July 2022

Abstract
Background
The completeness of the intervertebral disc proteome is fundamental to the integrity and functionality of the intervertebral disc.

Methods
The 20 experimental rats were placed into two groups randomly, normal group (NG) and acupuncture pathological degeneration group-2 weeks (APDG-2w). The ten 24-month-old rats were grouped into physiological degeneration group (PDG). Magnetic resonance imaging, X-ray examination, histological staining (hematoxylin & eosin, safranin-O cartilage, and alcian blue staining), and immunohistochemical examination were carried out for assessing the degree of disc degradation. Intervertebral disc was collected, and protein composition was determined by LC- MS, followed by bioinformatic analysis including significance analysis, subcellular localization prediction, protein domain prediction, GO function and KEGG pathway analysis, and protein interaction network construction. LC-PRM was done for protein quantification.

Results
Physiological degeneration and especially needle puncture decreased T2 signal intensity and intervertebral disc height. Results from hematoxylin & eosin, safranin-O, and alcian blue staining revealed that the annulus fibrosus apparently showed the wavy and collapsed fibrocartilage lamellas in APDG-2w and PDG groups. The contents of the nucleus pulposus were decreased in physiological degeneration group and APDG-2w group compared with NG. Results from immunohistochemical analysis suggested the degeneration of intervertebral disc and inflammation in APDG-2w and PDG groups. The protein composition and expression between needle puncture rat models and the physiological degeneration group showed significant difference.

Conclusions
Our studies produced point-reference datasets of normal rats, physiological degeneration rats, and needle puncture rat models, which is beneficial to subsequent pathological studies. There is differential expression of protein expression in degenerative discs with aging and acupuncture, which may be used as a potential discriminating index for different intervertebral degenerations.
Reuniting the Three Sisters: collaborative science with Native growers to improve soil and community health
Authors: Kapayou D. G. , Herrighty E. M. , Hill C. Gish , Camacho V. Cano , Nair A. , Winham D. M. , McDaniel M. D. 
Published: July 2022

AbstractBefore Euro-American settlement, many Native American nations intercropped maize (Zea mays), beans (Phaseolus vulgaris), and squash (Cucurbita pepo) in what is colloquially called the “Three Sisters.” Here we review the historic importance and consequences of rejuvenation of Three Sisters intercropping (3SI), outline a framework to engage Native growers in community science with positive feedbacks to university research, and present preliminary findings from ethnography and a randomized, replicated 3SI experiment. We developed mutually beneficial collaborative research agendas with four Midwestern US Native American nations. Ethnographic data highlighted a culturally based respect for 3SI as living beings, the importance it holds for all cultural facets of these Native nations, and the critical impact the practice has on environmental sustainability. One concern expressed by Native growers during ethnographic research was improving soil health—part of the rationale for establishing the 3SI agronomic experiment. To address this, we collaboratively designed a 3SI experiment. After 1 year, 3SI increased short-term soil respiration by 24%, decreased salt-extractable nitrate by 54%, had no effect on soil microbial biomass (but increased its carbon-to-nitrogen ratio by 32%) compared to the average of monoculture crops. The overarching purpose of this collaborative project is to develop a deeper understanding of 3SI, its cultural importance to Native communities, and how reinvigorating the practice—and intercropping in general—can make agroecosystems more sustainable for people and the environment.
Discrimination between softwood and hardwood based on hemicellulose content obtained with portable nuclear magnetic resonance
Authors: Stagno Valeria , Ricci Sara , Longo Sveva , Verticchio Elena , Frasca Francesca , Siani Anna Maria , Capuani Silvia 
Published: July 2022

AbstractWood is a hygroscopic material that can reach an equilibrium moisture content when ambient temperature and relative humidity are constant. Moisture affects all properties of wood, as well as its preservative treatment. The hygroscopic behavior of wood can be attributed to the hydroxyl groups of its constituents. Since hemicellulose shows the greatest water affinity, it can be considered the main responsible for the ingress of water into the wood mass. Below the fiber saturation point, wood moisture is only stored in the cell walls. Proton Nuclear Magnetic Resonance (NMR) is a relative method used for the evaluation of moisture content distribution in wood and NMR relaxation is an excellent tool to study the hygroscopic behavior of different woods below the fiber saturation point. This work aimed to test the hypothesis of discriminating among softwoods and hardwoods of different botanical species and identifying further sub-clusters of woods based on the NMR proton spin–spin (T2) and spin–lattice (T1) relaxation times of their cell wall water in the hygroscopic moisture range. Importantly, the study was performed using a portable low-cost NMR instrument with which it is possible to investigate wood samples of any size. The main result of this study was that at RH = 94% the relaxation time T2,2, associated with the cell wall bound water, can be used as a marker to discriminate among softwoods and hardwoods.
Graphical abstract
Exploring land use determinants in Italian municipalities: comparison of spatial econometric models
Authors: Punzo Gennaro , Castellano Rosalia , Bruno Emma 
Published: July 2022

AbstractThis study sets up a spatial econometric framework to explore the factors that best describe land consumption in Italy at the municipal level. By modelling the different types of spatial interactions and geographical proximity between all Italian municipalities, the direct effects of land use drivers are assessed together with spillover effects. Land use data are drawn from the ISPRA-SNPA 82/18 Report and cover all 7,998 Italian municipalities. The results highlight the existence of endogenous and exogenous interaction effects and the crucial role of the demographic, socio-economic and institutional structure on land use intensity. Hence the need for a planning policy aimed at: i) strengthening institutional cooperation to deal with excessive administrative fragmentation; ii) improving institutional and governmental quality to trigger virtuous mechanisms for sustainable land use management.
Janina Hosiasson-Lindenbaum on Analogical Reasoning: New Sources
Authors: Sznajder Marta 
Published: July 2022

AbstractJanina Hosiasson-Lindenbaum is a known figure in philosophy of probability of the 1930s. A previously unpublished manuscript fills in the blanks in the full picture of her work on inductive reasoning by analogy, until now only accessible through a single publication. In this paper, I present Hosiasson’s work on analogical reasoning, bringing together her early publications that were never translated from Polish, and the recently discovered unpublished work. I then show how her late work relates to Rudolf Carnap’s approach to “analogy by similarity” developed in the 1960s. Hosiasson turns out to be a predecessor of the line of research that models analogical influence as inductive relevance. A translation of Hosiasson’s manuscript concludes the paper.
Higher intracranial pressure variability is associated with lower cerebrovascular resistance in aneurysmal subarachnoid hemorrhage
Authors: Svedung Wettervik Teodor , Engquist Henrik , Howells Timothy , Hånell Anders , Rostami Elham , Ronne-Engström Elisabeth , Lewén Anders , Enblad Per 
Published: July 2022

AbstractHigher intracranial pressure variability (ICPV) has been associated with a more favorable cerebral energy metabolism, lower rate of delayed ischemic neurologic deficits, and more favorable outcome in aneurysmal subarachnoid hemorrhage (aSAH). We have hypothesized that higher ICPV partly reflects more compliant and active cerebral vessels. In this study, the aim was to further test this by investigating if higher ICPV was associated with lower cerebrovascular resistance (CVR) and higher cerebral blood flow (CBF) after aSAH. In this observational study, 147 aSAH patients were included, all of whom had been treated in the Neurointensive Care (NIC) Unit, Uppsala, Sweden, 2012–2020. They were required to have had ICP monitoring and at least one xenon-enhanced computed tomography (Xe-CT) scan to study cortical CBF within the first 2 weeks post-ictus. CVR was defined as the cerebral perfusion pressure in association with the Xe-CT scan divided by the concurrent CBF. ICPV was defined over three intervals: subminute (ICPV-1m), 30-min (ICPV-30m), and 4 h (ICPV-4h). The first 14 days were divided into early (days 1–3) and vasospasm phase (days 4–14). In the vasospasm phase, but not in the early phase, higher ICPV-4h (β =  − 0.19, p < 0.05) was independently associated with a lower CVR in a multiple linear regression analysis and with a higher global cortical CBF (r = 0.19, p < 0.05) in a univariate analysis. ICPV-1m and ICPV-30m were not associated with CVR or CBF in any phase. This study corroborates the hypothesis that higher ICPV, at least in the 4-h interval, is favorable and may reflect more compliant and possibly more active cerebral vessels.
A variational framework for the inverse Henderson problem of statistical mechanics
Authors: Frommer Fabio , Hanke Martin 
Published: July 2022

AbstractThe inverse Henderson problem refers to the determination of the pair potential which specifies the interactions in an ensemble of classical particles in continuous space, given the density and the equilibrium pair correlation function of these particles as data. For a canonical ensemble in a bounded domain, it has been observed that this pair potential minimizes a corresponding convex relative entropy functional, and that the Newton iteration for minimizing this functional coincides with the so-called inverse Monte Carlo (IMC) iterative scheme. In this paper, we show that in the thermodynamic limit analogous connections exist between the specific relative entropy introduced by Georgii and Zessin and a proper formulation of the IMC iteration in the full space. This provides a rigorous variational framework for the inverse Henderson problem, valid within a large class of pair potentials, including, for example, Lennard-Jones-type potentials. It is further shown that the pressure is strictly convex as a function of the pair potential and the chemical potential, and that the specific relative entropy at fixed density is a strictly convex function of the pair potential. At a given reference potential and a corresponding density in the gas phase, we determine the gradient and the Hessian of the specific relative entropy, and we prove that the Hessian extends to a symmetric positive semidefinite quadratic functional in the space of square integrable perturbations of this potential.
Two new parasitic copepods of the family Sphyriidae (Copepoda: Siphonostomatoida) from Australian elasmobranchs
Authors: Boxshall Geoff A. , Barton Diane P. , Kirke Amy , Zhu Xiaocheng , Johnson Grant 
Published: July 2022

AbstractTwo new species of the genus Tripaphylus Richiardi in Anonymous, 1878 (family Sphyriidae) are described from elasmobranch hosts caught as bycatch within the Demersal and Timor Reef Fisheries which operate in the Northern Territory exclusive economic zone. Tripaphylus squidwardin. sp. was collected from Carcharhinus coatesi Whitley and had a prevalence of 11.6%. Tripaphylus dippenaaraen. sp. was collected from Rhizoprionodon acutus (Rüppell) and had a prevalence of 28.2%. The new species are distinguished from existing congeneric species by the body proportions and shape of the adult female and by the arrangement of lobes on the ventral surface of the cephalothorax.
Plasma nervonic acid levels were negatively associated with attention levels in community-living older adults in New Zealand
Authors: de Seymour Jamie V , Beck Kathryn L , Conlon Cathryn A , von Hurst Pamela R , Mumme Karen D , Haskell-Ramsay Crystal F , Jones Mary Beatrix 
Published: July 2022

AbstractThe global population is aging. Preserving function and independence of our aging population is paramount. A key component to maintaining independence is the preservation of cognitive function. Metabolomics can be used to identify biomarkers of cognition before noticeable deterioration. Our study investigated the plasma metabolome of 332 community-living New Zealanders between 65 and 74 years of age, using gas chromatography-mass spectrometry. Six cognitive domains were assessed. Of the 123 metabolites identified using an in-house mass spectral libraries of standards, nervonic acid had a significant, inverse association with the attention domain (P-value = 1.52E− 4; FDR = 0.019), after adjusting for covariates (apolipoprotein E -ε4 genotype, sex, body fat percentage (standardised by sex), age, education, deprivation index, physical activity, metabolic syndrome, polypharmacy, smoking status, and alcohol intake) and multiple testing. Attention is defined as the ability to concentrate on selected aspects of the environment while ignoring other stimuli. This is the first study to identify nervonic acid as a potential biomarker of attention in older adults. Future research should confirm this association in a longitudinal study.
Development and validation of three colorimetric charge transfer complexes for estimation of fingolimod as an antineoplastic drug in pharmaceutical and biological samples
Authors: Salem Hesham , Mazen Dina Z. , Heshmat Dina , Mahmoud Mohamed M. , Ali Ebtisam , Abdelaziz Amany 
Published: July 2022

AbstractAn inexpensive, simple, sensitive and validated approach is developed for estimation of fingolimod through production of colored charge transfer complexes of fingolimod with different electron acceptor reagents, including a reaction of fingolimod as n-donor with 7,7,8,8-tetracyanoquinodimethane, tetrachloro 1,4-benzoquinone and tetracyanoethylene and as n-acceptors, yielding colored and stable anions which were measured spectrophotometrically. The range that obeyed Beer’s law is 50–300 µg mL−1 for fingolimod with all the studied reagents. The various parameters that affect the reaction were studied and optimized. The results were statistically compared with a reported method showing equal precision and accuracy. The researched approaches were utilized to determine the cited drug in its pharmaceutical form and spiked human plasma with accepted accuracy and precision.
Adjustable superlubricity system using polyalkylene glycol with various acid aqueous solutions
Authors: Liu Wenrui , Wang Hongdong , Liu Yuhong 
Published: July 2022

AbstractPolyalkylene glycol (PAG) aqueous solutions have recently been demonstrated to exhibit an ultralow friction coefficient (COF, μ < 0.01). However, the prolonged running-in period and low bearing capacity have limited its widespread application. In this study, we determined that the running-in period can be decreased by more than 75% when the pH value of the lubricant is controlled at 3 by introducing various acid solutions. Additionally, less time was required to realize stable superlubricity with inorganic acid at lower pH values. This was mainly attributed to the acceleration effect of hydrogen ions around the contact region. In case of PAG aqueous solution with organic acid, the wear loss between sliding solid surfaces was reduced, and thus the bearing pressure during the superlubricity period was significantly improved from approximately 30 to 160 MPa. Furthermore, the organic acid molecules were considered to form strong hydrogen bonds with PAG macromolecules and solid surfaces. This in turn strengthened the structure of the adsorption layers. The unique effect of different acids in aqueous polymer lubrication can potentially significantly aid in advancing the study of polymer tribology and broadening industrial applications.
Stable oral lubrication enhancer obtained from thiolated polyethylene glycol and mucin
Authors: He Xiaoyan , Smart Pravin , Taufiqurrakhman Mohamad , Wang Chun , Bryant Michael 
Published: July 2022

AbstractMucins are vital components contributing to the unique lubrication properties of human whole saliva. For patients receiving medication and or treatment such as diabetes or radiotherapy, xerostomia (dry mouth) is a common with numerous and deleterious side effects. Although products exist on the market to relive the symptoms of Xerostomia there remains a drive to formulate a biocompatible lubricant that replicate the functionality offered by the natural biological environment. Herein, a combination of mucin and thiolated polyethylene glycol (PEG-SH) was proposed as a new saliva substitute. Mucin and PEG-SH molecules could form hydrated layers immediately by chemisorption. Meanwhile, the chemical interactions between mucin and PEG-SH molecules also promoted the formation of a mixed layer. All the pre-formed layers could decrease friction and had the potential to decrease wear, especially mucin and PEG-SH mixed layer when compared to mucin only solutions. Further investigations of tribological mechanism implied that the excellent lubrication performance of mixed layer with long effectiveness was contributed to the friction-reducing effect of PEG/mucin molecules and the mucoadhesive property of mucin. The study provides a guide for using mucin as a mucoadhesive agent to stable lubricative polymers with low molecular weight as novel salivary substitutes for lubrication.
Cartilage-bone inspired the construction of soft-hard composite material with excellent interfacial binding performance and low friction for artificial joints
Authors: Chen Qin , Zhang Xinyue , Liu Siyu , Chen Kai , Feng Cunao , Li Xiaowei , Qi Jianwei , Luo Yong , Liu Hongtao , Zhang Dekun 
Published: July 2022

AbstractInspired by the cartilage-bone structure in natural joints, soft-hard integrated materials have received extensive attention, which are the most promising candidates for artificial joints due to their combination of excellent load-bearing properties and lubricating properties. The latest progress showed that the combination of hydrogel and titanium alloy can realize a bionic natural joint lubrication system on the surface of titanium alloy. However, obtaining a tough interface between the hydrogel (soft and wet) and the titanium substrate (hard and dry) is still a great challenge. Here, we designed a “soft (hydrogel)-hard (Ti6Al4V)” integrated material with outstanding combination, which simulates the structure and function of cartilage-bone in the natural joint. The load-bearing properties, binding performance, and tribological behaviors for different forms of the soft-hard integrated materials were investigated. The results showed that the hydrogel layer and Ti6Al4V substrate possess ultra-high interfacial toughness (3,900 J/m2). In addition, the combination of the hydrogel layer and Ti6Al4V substrate provided a good lubrication system to endow the “soft (hydrogel)-hard (Ti6Al4V)” integrated material with high load-bearing and excellent tribological properties. Therefore, this study provided an effective strategy for prolonging the service life of Ti6Al4V in the biomedical field.
Conjoined Twins: Unicephalus Non-Janiceps Tetrapus Tetrabrachius
Authors: Yener Cem , Sayın N. Cenk , Altan Esra , Varol Füsun 
Published: July 2022

AbstractConjoined twins are an uncommon type of monoamniotic twins with an incidence of about 1.5 per 100,000 births worldwide. Non-janiceps is the extremely rare sub-type of cephalopagus which is reported as 1 in 58 of all conjoined twins or 1 in 3 million births. We present a G6, P5 31-year-old pregnant who was diagnosed with a unicephalus non-janiceps conjoined twins. Due to its incompatibility with life, the pregnancy was electively terminated. The prognosis of conjoined twins depends on the location and extent of the conjoined area and the accompanying congenital anomalies of the fetuses. Early diagnosis is vital because it can help in assessing the type of conjoined twins and subsequently pre-postnatal decision making. Elective termination of non-janiceps type of conjoined twins which is incompatible with life is a justifiable possibility.