bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eficacia del manejo de la litiasis renal con litotricia extracorpórea por ondas de choque (LEOCh) en la población pediátrica de un hospital de tercer nivel en México
Authors: Medrano-Urtecho Harvey Mauricio , Sánchez-Núñez Juan Eduardo , Acevedo-García Christian , Garduño-Arteaga Mateo Leopoldo , Rodríguez-Robles Jonathan Alonso , Sánchez-Meza José Eduardo , Maldonado-Ávila Miguel 
Published: February 2022

Introducción: La incidencia de litiasis urinaria en niños es baja (~3%). La litotricia extracorpórea por ondas de choque (leoch) es una alternativa terapéutica de primera línea para cálculos renales menores a 20mm. Sin embargo, posee algunas desventajas: la tasa de éxito es variable (después de la primera sesión oscila entre 60 - 90%), directamente asociado al tamaño, densidad y composición del lito. Los factores predictores del éxito del procedimiento son la carga litiásica, la longitud infundibular y el ángulo infundibulopélvico (> 45o).
Objetivo: Establecer la eficacia global de la leoch en litiasis renal en la población pediátrica del Hospital General de México.
Material y métodos: Estudio retrospectivo, transversal, analítico; incluyó 45 expedientes de pacientes pediátricos sometidos a leoch como manejo para litiasis renal. Criterios de inclusión: Edad: 1-18 años; lito </= 20mm, localización renal. Criterios de exclusión. Pacientes > 18 años, lito > 20mm, localización extrarrenal, presencia de obstrucción, embarazo y discrasia sanguínea. Criterios de eliminación: Paciente sin seguimiento (1 mes) radiológico.
Resultados: 28 pacientes alcanzaron la resolución de su estado de litiasis, tasa de éxito del 62.2% (ic 95% de 47.5 a 77.0). Los factores asociados a la falla terapéutica fueron el tamaño del lito (p=0.03) y su localización en la unidad renal (p= 0.03).
Conclusiones: Los resultados obtenidos en nuestro estudio para el manejo de la litiasis renal en la población pediátrica son similares a lo reportado en la literatura en cuanto a seguridad, eficacia y estado libre de litiasis.
Descripción de nueva técnica quirúrgica para reparación de pene palmeado
Authors: Chavolla Canal Alan Johan 
Published: February 2022

Antecedentes: El pene palmeado o cuerda peneana, es una patología congénita o adquirida poco comprendida, caracterizada por una cuerda en el escroto unida a la cara ventral del pene, se puede presentar en la población pediátrica con pocos síntomas, pero de grandes repercusiones en la vida adulta, por ello la necesidad de buscar nuevas técnicas quirúrgicas que mejoren el resultado funcional y estético.
Objetivo: Este trabajo pretende describir una nueva técnica quirúrgica en adultos, con los principios considerados como necesarios para corregir esta patología, se pretende describir la técnica a detalle y sus resultados, y así, tener una opción más para corregir la cuerda peneana.
Pacientes y métodos: Se captaron 2 pacientes adultos en un periodo de 4 meses en el Hospital General Regional número 46 del Instituto Mexicano del Seguro Social en Guadalajara Jalisco, México. Los cuales se clasificaron y sometieron a la técnica quirúrgica que se describe, con documentación visual para demostrar los resultados.
Resultados: Se realizo la técnica quirúrgica que consiste en una incisión en forma de v y redistribución del tejido formando una t, se realizó sin complicaciones tempranas o tardías y cumpliendo los estándares establecidos para la resolución de la cuerda peneana. Los pacientes estuvieron satisfechos con los resultados postquirúrgicos funcionales y estéticos
Conclusión: La técnica demostró ser eficaz para la corrección de cuerda peneana al realizar una modificación de la v-y de avance e introduciendo a la literatura el colgajo v-t de redistribución con el cual se mejoró los resultados estéticos y funcionales.
Tumor renal de células claras como debut de la enfermedad de Von Hippel-Lindau: reporte de caso
Authors: Martínez-Valeriano David Alejandro , Vásquez-Ciriaco Sergio , Jiménez-Rivera Elisa , García-Manzano Roberto Armando , Barker-Antonio Alan , Dávila-Ruiz Ediel Osvaldo , García-Espinoza Jaime Aron 
Published: February 2022

Background: Von Hippel-Lindau disease is caused by mutations of the VHL tumor-suppressor gene and results in the development of different neoplasias in the central nervous system, eye, and abdomen. Its incidence is low, but patients that develop clear cell renal cell carcinoma have the highest mortality rate.
Clinical case: A 45-year-old woman, with a family history of central nervous system and abdominal neoplasias, sought medical attention due to a progressively growing mass in the left flank. A kidney tumor was corroborated through an imaging study, and she underwent left radical nephrectomy. The diagnosis of clear cell renal cell carcinoma was confirmed. In the subsequent approach, she was also diagnosed with von Hippel-Lindau type I disease.
Conclusions: Von Hippel-Lindau disease presents with different neoplastic manifestations, and that of clear cell renal cell carcinoma has the highest morbidity and mortality rates. When there is a family history, its early detection is essential for improving outcome and opportunely diagnosing other neoplasias resulting from the disease.
Novedades en el diagnóstico y tratamiento de la infección de tracto urinario en adultos
Authors: Guzmán Natalia , García-Perdomo Herney Andrés 
Published: February 2022

Summary description of the topic: Urinary tract infections (UTIs) encompass any infection that involves the urinary tract. It is a frequent pathology in the hospitalization and outpatient services, which makes it essential to have knowledge of the risk groups, the causality, to offer prevention in patients who require it, follow-up protocols, understand who really requires extension studies and measures more specialized
Relevance: Being such a common clinical condition, it is not enough to achieve identification and treatment, but it is mandatory for health personnel to be aware of the conditions that require special care and timely treatments. In cases where it can be handled more specifically, it should be very reasonable with antibiotic treatments to avoid antimicrobial resistance.
Conclusions: The UTIs has high costs dedicated to initial management and complications. The new diagnostic methods will be of vital importance in their management, as they can offer therapies directed to the pathogen in a more timely manner and avoid the antimicrobial resistance that is one of the great conflicts today. The new medications may offer more accurate management in cases of multiple antimicrobial resistance.
El poder de las redes sociales en urología. Panorama actual del gremio de residentes de la Sociedad Mexicana de Urología (SMU)
Authors: Sánchez-Núñez Juan Eduardo , Cabrera-Mora Norma Alejandra , Magaña-González Jorge Esteban , Rosas-Nava Jesús Emmanuel , Jaspersen-Gastélum Jorge , Acevedo-García Christian 
Published: February 2022

Introduction: Social networks enable their users to create, share, comment on, and transfer multimedia among millions of internet users in real time. The urology social media hashtag, #UroSoMe, provides an excellent opportunity to find and exchange health information.
Objective: To evaluate the current situation in relation to #UroSoMe among the community of urologists in training associated with the Sociedad Mexicana de Urología (SMU), a highly relevant Mexican professional organism.
Materials and methods: : A descriptive, cross-sectional study was conducted by means of an online survey on the sociodemographic characteristics of social media users and their associated perceptions and use of social media. Fifty-two questionnaires were completed.
Results: A total of 80.8% (n=42) of those surveyed were men and 19.2% (n=10) were women. Facebook ® (78.8%) and Instagram ® (51.9%) were the favored social networks utilized for social communication among residents and 78.8% (n=41) used them personally (for leisure) and professionally.
Discussion: #UroSoMe is useful in urologic activity, especially from the perspective of communication and connectivity among professionals.
Conclusions: Social networks have become a tool for healthcare professionals to communicate with one another. Urology residents associated with the SMU find them useful for keeping updated and establishing professional connections. Safeguarding the quality, security, and correct use of information shared on social media is a great challenge.
Incidencia y características clínicas de pacientes con tuberculosis genitourinaria durante el período 2003 a 2019 en un centro hospitalario de tercer nivel.
Authors: Gallegos-Sánchez Gustavo , Rosales-Velázquez César Eduardo , Ruvalcaba-Oceguera Guillermo Enrique , Aragón-Castro Marco Antonio , Gutiérrez-Rosales Rubén , Ordoñez-Jurado Aldo Uriel 
Published: February 2022

Objective: To evaluate the incidence, clinical characteristics, and treatment of genitourinary tuberculosis (GUTB) in adult patients at our hospital, within the time frame of 2003-2019.
Design and methodology: A retrospective study was conducted on 18 patients (11 men and 7 women). The inclusion criteria were patients >18 years of age with GUTB (ICD-10-CM Diagnosis Code A18.1) that were hospitalized and treated at the Centro Médico ISSEMyM Toluca, within the period of January 2003 to December 2019.
Results: Renal tuberculosis was found in 7 patients and bladder tuberculosis in 3. Testicular, prostate, and ovarian tuberculosis were each found in 2 patients, one case presented with ureteral tuberculosis, and one case with adrenal gland tuberculosis. Mean patient age was 44.1 years (range: 23-79 years). Men accounted for 61.1% of the patients and women, 38.9%. Mean time from symptom onset to clinical diagnosis was ≥12 months (50%). Signs and symptoms: fever (61.1%), hematuria (55.6%), weakness (44.4%), lumbar pain (38.9%), weight loss (38.9%), and irritative symptoms of the urinary tract (33.3%). Diagnoses were confirmed through bacteriologic (55%), histopathologic (83%), and molecular (11%) methods. Urologic or gynecologic intervention was required in 100% of the patients. The standard 4-drug treatment was the preferred regimen (88.9%) and mean treatment duration was 11 ± 2 months. There were no posttreatment-related deaths.
Limitations: A retrospective study with a small number of patients.
Originality or value: To know the epidemiology of GUTB at our hospital center to improve the evaluation approach to patients and make opportune diagnoses, in an effort to reduce morbidity and mortality.
Conclusions: The early approach to GUTB is extremely important for ruling it out, treating it opportunely, and reducing permanent damage and death as much as possible.
Fístula arteriovenosa como complicación de nefrolitotomía percutánea en paciente con riñón en herradura
Authors: Pulido-Contreras Enrique , Medrano-Sánchez Javier , González Villegas Hedler Olaf , Bautista López German 
Published: February 2022

Clinical case description: A 48-year-old man had a history of giant platelet disorder and diagnosis of horseshoe kidney with kidney stones. Standard 24 Fr percutaneous nephrolithotomy was performed. Ten days after surgery, the patient presented with clot-forming gross hematuria, resulting in anemia. Arteriovenous fistula was suspected and evaluation at the interventional cardiology service was ordered. Arteriovenous fistula diagnosis was confirmed and superselective embolization was performed in the anterior and posterior segmental artery, with complete resolution of the hematuria.
Relevance: To present the uncommon, post-percutaneous nephrolithotomy complication of hematuria secondary to arteriovenous fistula that was resolved through a minimally invasive technique in a patient with a kidney fusion anomaly.
Clinical implications: To take measures in that patient group to reduce what can be a life-threatening complication, managing it through superselective embolization to prevent kidney function deterioration.
Conclusions: Color Doppler ultrasound-guided percutaneous access aids in the prevention of injury to the renal vasculature during puncture and the use of miniaturized tracts can reduce the development of segmental artery lesion that could later condition fistula formation. Embolization is safe and effective in that group of patients.
Antimicrobial resistance and extended spectrum beta-lactamases in urinary tract infections: A serious problem in Northern Mexico
Authors: Robles-Torres José Iván , Ocaña-Munguía Marco Alberto , Madero-Morales Pedro Antonio , Ruíz-Galindo Efraín , Garza-González Elvira , Gómez-Guerra Lauro Salvador 
Published: February 2022

Objective: To describe the causal agents, prevalence of antimicrobial resistance, and risk factors associated with extended spectrum beta-lactamase (ESBL)-producing agents in urinary tract infections (UTIs).
Materials and methods: A retrospective study was conducted at a tertiary care hospital in Monterrey, Mexico. Inclusion criteria were patients that clinically presented with a UTI and had a positive urine culture, within the time frame of March to October 2017. The association with ESBL-producing agents was determined through the Χ2 test for categorical variables. Statistical significance was set at a p <0.05, utilizing SPSS version 20.0 software.
Results: A total of 353 positive urine cultures were confirmed. ESBL production was found in 21.5% of the strains. There was a high level of resistance (>50%) to amoxicillin-clavulanate, ciprofloxacin, levofloxacin, fosfomycin, and trimethoprim-sulfamethoxazole and moderate resistance (10-50%) to gentamicin and ceftriaxone. Amikacin, ertapenem, nitrofurantoin, and colistin had the lowest resistance rates (<10%). The ESBL-producing agents were associated with complicated UTI (p≤0.0001). The comorbidities associated with ESBL-positive UTIs were diabetes mellitus (p=0.02) and immunodeficiency (p=0.008), as was having undergone radiotherapy (p=0.025) and previous antibiotic use (p≤0.001).
Limitations: The clonal relationship of isolates, especially of E. coli, was not analyzed. We could not establish whether there was a high level of genetic diversity between the isolates or whether independent acquisition or cross-transmission occurred.
Value: We evaluated the epidemiologic characteristics of the ESBL-producing agents in UTIs at a Mexican tertiary care hospital.
Conclusions: One out of every five UTIs was caused by ESBLs in our study population. There was a high level of resistance to the antibiotics used as first-line empiric therapy in the patients studied.
Acute bacterial nephritis. A descriptive study of an underdiagnosed entity
Authors: Madero-Morales Pedro Antonio , Pallares-Méndez Rigoberto , Romero-Mata Rodrigo , Vizcarra-Mata Guillermo , Guillén-Lozoya Andrés 
Published: February 2022

Background: Acute bacterial nephritis is an infectious process diagnosed through imaging studies. The clinical course of the disease has been shown to be more aggressive than acute pyelonephritis. It continues to be underdiagnosed, thus there are few studies on the entity in the literature.
Objective: To describe the clinical characteristics and imaging features of acute bacterial nephritis, as well as its clinical course.
Design: A descriptive, retrospective case series was conducted.
Materials and methods: Thirty-two cases of acute bacterial nephritis in patients admitted to the hospital within the time frame of 2009 to 2016 were reviewed. The patients’ clinical characteristics upon admission were registered, as well as inpatient clinical progression, culture results, and antibiotic therapy response. The imaging studies were re-evaluated and the diagnostic consistency with either the focal or multifocal disease presentation was confirmed.
Results: Cases predominated in women (n=29, 90.62%) and the most frequently associated comorbidities were diabetes (n=16, 50%) and obesity (n=9, 28.25%). The most important clinical findings upon admission were fever (n=15, 46.87%) and leukocytosis (n=27, 84.38%). Escherichia coli was the most commonly isolated bacterium (63.63%). Both acute focal bacterial nephritis and acute multifocal bacterial nephritis were observed in 46.87% (n=15) and 53.13% (n=17) of the patients, respectively. Imaging studies were required for all diagnoses.
Conclusion: Fever and leukocytosis are the main findings in acute bacterial nephritis. Imaging studies are necessary for making the diagnosis, given that acute pyelonephritis and acute bacterial nephritis cannot be clinically differentiated.
Nefrectomía parcial laparoscópica y asistida por robot en pacientes con tumor renal
Authors: Soto-Vázquez Teresita , Almeida-Magaña Ricardo , Villeda-Sandoval Christian Isaac 
Published: February 2022

Background: Kidney cancer accounts for 2% of cancer deaths in Mexico. Partial nephrectomy has become the treatment of choice for renal tumors <4cm and can be carried out utilizing minimally invasive techniques.
Aim: To describe the perioperative, oncologic, and follow-up characteristics of patients that underwent partial laparoscopy with the robotic-assisted or laparoscopic approach at our hospital center.
Methods: A descriptive, retrospective cases series was conducted on patients that underwent minimally invasive partial nephrectomy at the Centro Médico Naval, within the time frame of February 2016 to February 2019.
Results: Sixteen patients had a BMI >25 kg/m2, initial creatinine was 0.97mg/dl, surgery duration was 202 minutes, blood loss was 300 ml, and 13 patients underwent warm ischemia, for a median of 24 minutes. Hospital stay was 3 days, 2 patients presented with complications, and serum creatinine at day 30 was 1.05 mg/dl. The 17 patients that presented with cancer all had clear cell renal cell carcinoma. Thirteen of those patients had nuclear grade 2 and 3 had positive margins.
Conclusions: Our good short-term oncologic and functional results were similar to those reported in the international literature. Comparison with the national literature is difficult, given the lack of studies employing the robotic approach.
Recurrencia de estenosis ureteropiélica posterior a tratamiento primario: prevalencia, factores asociados y tratamiento laparoscópico
Authors: Gonzalez-Cuenca Eduardo , Medrano-Urtecho Harvey Mauricio , Corona-Montes Víctor Enrique , Maldonado-Ávila Miguel , Rosas-Nava Jesús Emmanuel 
Published: February 2022

Aim: Our primary aim was to report the prevalence of recurrent stricture following primary pyeloplasty and the secondary treatment performed. The secondary aim was to identify the clinical or surgical factors related to recurrent ureteropelvic junction obstruction (UPJO).
Materials and methods: A retrospective study was conducted on patients diagnosed with UPJO at the Hospital General de México “Dr. Eduardo Liceaga”, between 2011-2019. Patients that underwent primary pyeloplasty, and developed recurrent UPJO, underwent secondary treatment, and had follow-up ³6 months were included in the study. A descriptive analysis was carried out.
Results: A total of 52 patients underwent open or laparoscopic pyeloplasty as primary treatment and 6 of them (11.5%) presented with recurrent UPJO at 44 months (median). Two of those patients presented with a non-functioning kidney and underwent simple laparoscopic nephrectomy and the remaining 4 patients underwent transperitoneal laparoscopic redo pyeloplasty as secondary treatment. The mean age of the patients with recurrence was 46 years, their mean BMI was 32.57±5 kg/m2, and two of them had urinary diversion prior to the primary pyeloplasty. Surgery duration was longer for laparoscopic redo pyeloplasty versus primary pyeloplasty (192 minutes versus 113 minutes) and intraoperative bleeding was similar (52cc versus 52.9cc). The surgical and histologic finding in laparoscopic redo pyeloplasty was peri-ureteral fibrosis. No aberrant vessels were found. Stricture was longer than 15 mm in the patients that underwent laparoscopic redo pyeloplasty (n=4). Obesity, lithiasis, and stricture length >15mm were more frequent in the patients with recurrence.
Conclusions: The prevalence of UPJO in our study population was 11.5%, which concurs with international parameters. Laparoscopic redo pyeloplasty is a useful tool in cases of UPJO.
Radium 223 en tiempos de COVID-19
Authors: Barreiro Diego , Mena-Cortes Danny Roberto 
Published: February 2022

Contexto clínico
Para el tratamiento del cáncer de próstata resistente a la castración (CPRC) metastásico se deben utilizar tratamientos que proporcionen beneficio en sobrevida global.
Los pacientes metastásicos sensibles a castración recibirirán tratamientos hormonales de segunda generación o taxanos. Aproximadamente el 80% de estos pacientes son tratados con hormonas de última generación.
Etiology of testicular pain 2019: Classification into ten logical subgroups
Authors: Uribe-Arcila Juan Fernando , Delgado-Montoya Andrés , Gaviria-Gil Federico 
Published: February 2022

Background: Testicular pain encompasses a vast medical diagnostic field, with numerous organ and system convergence. Acute testicular pain is a medical emergency that requires accurate evaluation and immediate resolution, whereas chronic testicular pain is enigmatic and requires sound knowledge of the mechanisms of testicular pain and the differential diagnosis.
Objective: To review the causes of testicular pain and propose a new etiologic classification consisting of 10 subgroups.
Methods: A bibliographic search was carried out utilizing Google and the National Library of Medicine’s PubMed databases to identify original articles and review articles (hard copy or electronic) published on testicular pain, up to March 2020. The search included: MeSH terms: testicular disease (classification, complications, etiology, trauma, microbiology, pathology, pathophysiology, secondary, surgery, treatment) and vasectomy; Non-MeSH terms: acute and chronic orchialgia, scrotalgia, orchidynia, groin pain, epididymalgia, testalgia, chronic testicular pain, chronic scrotal pain syndrome, testicular pain syndrome, epididymal pain syndrome, and post-vasectomy pain syndrome. The initial search produced 625 articles, of which 143 were included in the present review.
Results: To better understand testicular pain etiology, 100 possible diagnoses were divided into ten subgroups: infectious, neoplastic, traumatic, torsional, vascular, immunologic, neurologic, pharmacologic, obstructive, and miscellaneous causes. Likewise, treatment can be divided into two main groups, according to therapeutic options: pharmacologic and non-pharmacologic, with the latter subdivided into: noninvasive and the increasingly performed invasive (surgical) alternatives.
Conclusions: Testicular pain should be understood as a complex pain syndrome of enigmatic origin. Treatment success depends on the correct identification, from hundreds of possibilities, of the cause of pain. Logical grouping of those possibilities could aid in making the accurate etiologic identification.
Virus del papiloma humano (VPH): microbiología, relación con el cáncer de pene y características de la vacuna
Authors: Rengifo-Rodríguez Javier Eduardo , Osorio Julio César , García-Perdomo Herney Andrés 
Published: February 2022

Over the past two decades, human papillomavirus (HPV) has been an important object of study due to its causal relation to cervical cancer and its association as a risk factor for anogenital neoplasias, especially penile cancer (PC).
The molecular study of HPV and the identification of essential proteins led to the development of the vaccine, and a clear epidemiologic relation between HPV and PC has also been identified. With respect to the molecular aspect of that association, the alteration of the P16 cellular pathway by the oncoproteins of the virus is evident, but it is not thought to be the only pathogenic mechanism. The vaccine appears to be effective in preventing HPV infection but there is not sufficient evidence that it protects against PC.
Therefore, more research is needed, both in the clinical area, to determine whether the vaccine is definitively effective/efficacious in the prevention of PC, and in molecular biology, studying the molecular mechanisms involved in the pathogeny of that neoplasia.