bluuebunny/crossref_metadata_2025_split huggingface dataset:
Caustic Ingestion in Children
Authors: Shcherbaeva Tanya , Muallem Kalmovich Limor , Shalem Tzippora , Broide Efrat , Gavriel Haim , Pitaro Jacob 
Published: May 2022

Objectives
Caustic ingestion in children is a significant cause of morbidity despite preventive measures. Upon arrival to the emergency department, these children are often initially seen by the otolaryngologist and later on by the gastroenterologist. This study aimed to determine which otolaryngological and gastrointestinal signs and symptoms can better predict abnormal findings on imaging, esophagogastroduodenoscopy (EGD), and complications development.

Methods
We performed a retrospective chart review of children 18 years or younger admitted because of caustic ingestion between January 2007 and November 2019.

Results
Forty-one children with a median age of 4.2 years (interquartile range, 1.7–16.7 years) were included; of them, 22 (53.6%) were males. Nineteen children (46.3%) underwent EGD, which revealed no pathology in 13 cases (68.4%). Most ingested substances were in the form of liquid (82.9%), accidentally ingested (82.9%), and with an alkaline pH (57.5%). Stridor, dyspnea, drooling, abnormal oral cavity findings, dysphagia, and vomiting were significantly associated with pathological findings on imaging and/or EGD and/or complications development (P = 0.028, P = 0.028, P = 0.022, P = 0.02, P < 0.001, and P = 0.01 respectively). Laryngopharyngeal group of findings (dyspnea, stridor, hoarseness, sore throat, and/or drooling) predicted a higher risk for complications development than the gastrointestinal group (dysphagia, abdominal pain, vomiting, or abdominal swelling and/or tenderness) (P = 0.011, P = 0.31 respectively).

Conclusions
In children, after caustics ingestion, laryngopharyngeal signs and symptoms may predict a higher risk for complications development in comparison with gastrointestinal signs and symptoms. We therefore stress the importance of otolaryngological examination upon arrival to the emergency department.
Point-of-Care Ultrasound Assessment of Orbital Rhabdomyosarcoma in a Pediatric Patient
Authors: Nichols Francesca R. , Nguyen Mylinh T. , Ekpenyong Atim , Pade Kathryn H. 
Published: May 2022

Abstract
Rhabdomyosarcoma is the most common soft tissue tumor in children and orbital lesions account for 10% of these diagnoses. This case describes a young boy who presented with eyelid swelling that was initially concerning for an expanding hematoma given a history of recent trauma to the eye. Point-of-care ultrasound identified 2 distinct lesions surrounding the globe, which prompted further investigation, including ophthalmology consult and computed tomography. The case presented highlights the initial misdiagnosis on both point-of-care ultrasound and computed tomography and the importance of using color Doppler on ultrasound to distinguish an orbital rhabdomyosarcoma from a posttraumatic hematoma.
Prediction Of The Impact Of Genetic Variability On Drug Sensitivity For Clinically Relevant EGFR Mutations
Authors: Suriñach Aristarc , Hospital Adam , Westermaier Yvonne , Jordà Luis , Orozco-Ruiz Sergi , Beltrán Daniel , Colizzi Francesco , Andrio Pau , Soliva Robert , Municoy Martí , Gelpí Josep Lluís , Orozco Modesto 
Published: May 2022

ABSTRACTMutations in the kinase domain of the Epidermal Growth Factor Receptor (EGFR) can be drivers of cancer and also trigger drug resistance in patients under chemotherapy treatment based on kinase inhibitors use. A priori knowledge of the impact of EGFR variants on drug sensitivity would help to optimize chemotherapy and to design new drugs effective against resistant variants. To this end, we have explored a variety of in silico methods, from sequence-based to ‘state-of-the-art’ atomistic simulations. We did not find any sequence signal that can provide clues on when a drug-related mutation appears and what will be the impact in drug activity. Low-level simulation methods provide limited qualitative information on regions where mutations are likely to produce alterations in drug activity and can predict around 70% of the impact of mutations on drug efficiency. High-level simulations based on non-equilibrium alchemical free energy calculations show predictive power. The integration of these ‘state-of-the-art’ methods in a workflow implementing an interface for parallel distribution of the calculations allows its automatic and high-throughput use, even for researchers with moderate experience in molecular simulations.
Comparative genomics reveals insight into the evolutionary origin of massively scrambled genomes
Authors: Feng Yi , Neme Rafik , Beh Leslie Y. , Chen Xiao , Braun Jasper , Lu Michael , Landweber Laura F. 
Published: May 2022

SummaryCiliates are microbial eukaryotes that undergo extensive programmed genome rearrangement that converts long germline chromosomes into smaller gene-rich somatic chromosomes. Three well-studied ciliates includeOxytricha trifallax,Tetrahymena thermophilaandParamecium tetraurelia, but only theOxytrichalineage has a massively scrambled genome whose assembly requires hundreds of thousands of precise DNA joining events. Here we study the emergence of genome complexity by examining the origin and evolution of discontinuous and scrambled genes in theOxytrichalineage.We sequenced, assembled and annotated the germline and somatic genomes ofEuplotes woodruffiand the germline genome ofTetmemena sp., and compared their genome rearrangement features to that of the model ciliateOxytricha trifallax. The germline genome ofTetmemenais as massively scrambled and interrupted asOxytricha’s: 13.6% of its gene loci rearrange via translocations and/or inversions. This study revealed that the earlier-diverged spirotrich,E. woodruffi, also has a scrambled genome, but approximately half as many loci (7.3%) are scrambled, supporting its position as a possible evolutionary intermediate in this lineage, in the process of accumulating complex genome rearrangements. Scrambled loci are more often associated with local duplications, supporting a simple model for the origin of scrambled genes via DNA duplication and decay.
The effects of utilitarian value on omnichannel continuance intention: the moderating role of product involvement
Authors: Geng Lixiao , Chang Yaping 
Published: May 2022

PurposeThis study aims to examine the factors that motivate consumers’ omnichannel continuance intention from the utilitarian value perspective and to test the moderating role of product involvement.Design/methodology/approachStructural equation modeling was used to analyze the research model with data on 382 omnichannel consumers.FindingsThree perceived utilitarian value dimensions – quality, monetary savings and convenience – positively influence consumers’ omnichannel continuance intention through their attitudes. Convenience is the main driver of consumers’ omnichannel shopping. Moreover, the effect of perceived quality on attitude is greater for consumers with low rather than high product involvement.Research limitations/implicationsThis study refines the research on omnichannel consumer behavior, adds to the factors known to influence consumers’ omnichannel selection and identifies the critical role of product involvement in retaining consumers. However, it only investigates the basic dimensions of perceived utilitarian value and does not distinguish between types of omnichannel services. Future research can expand upon consumer intention by considering more utilitarian values and omnichannel services.Practical implicationsOmnichannel retailers should consider the significance of these findings in guiding consumer retention and channel integration. Specifically, they may suggest more convenient methods for shopping and measures of consumer product involvement to provide utilitarian value.Originality/valueThis study adds to the literature on omnichannel selection by investigating consumers’ continuance intention. Analyzing the effects of utilitarian value extends prior research on information systems, channel integration, supply chain management and consumer experience.
How does technology sourcing in organizational ambidexterity produce high venture performance?
Authors: Su Taoyong , Yu Yuzhu , Li Yuanqing , Zhang Jintao 
Published: May 2022

Purpose
Based on a theoretical framework of ambidexterity in technology sourcing beyond organizational and technological boundaries, this study aims to explore how start-ups balance technology sourcing in organizational ambidexterity (TSOA) to produce high venture performance.

Design/methodology/approach
A questionnaire survey is distributed among start-ups in the science and technology park of a university in eastern China, producing a total of 45 valid responses. The fuzzy-set approach to qualitative comparative analysis is used in this study.

Findings
The findings show that start-ups achieve high venture performance through external technology sourcing (external exploration and exploitation) in the initial stage. In the growth stage, start-ups adopt external and internal technology sourcing (internal exploration and exploitation) to produce high venture performance. The technology sourcing strategy in ambidextrous activity for start-ups is punctuated equilibrium and evolving from the external ambidexterity to internally and externally coordinate ambidexterity at entrepreneurial stages.

Originality/value
This study creatively adopts configuration-based thinking to investigate how to balance TSOA for high venture performance, extending the literature on technology sourcing and contributing to the balance theory of exploration and exploitation.
Towards co-created food well-being: culinary consumption, braggart word-of-mouth and the role of participative co-design, service provider support and C2C interactions
Authors: Taheri Babak , Pourfakhimi Shahab , Prayag Girish , Gannon Martin J. , Finsterwalder Jörg 
Published: May 2022

PurposeThis study aims to investigate whether the antecedents of co-creation influence braggart word-of-mouth (WoM) in a participative leisure context, theorising the concept of co-created food well-being and highlighting implications for interactive experience co-design.Design/methodology/approachA sequential mixed-method approach was used to test a theoretical model; 25 in-depth interviews with cooking class participants were conducted, followed by a post-experience survey (n= 575).FindingsQualitative results suggest braggart WoM is rooted in active consumer participation in co-designing leisure experiences. The structural model confirms that participation in value co-creating activities (i.e. co-design, customer-to-customer (C2C) interaction), alongside perceived support from service providers, increases consumer perceptions of co-creation and stimulates braggart WoM. Degree of co-creation and support from peers mediate some relationships.Research limitations/implicationsLimited by cross-sectional data from one experiential consumption format, the results nevertheless demonstrate the role of active participation in co-design and C2C interactions during value co-creation. This implies that co-created and co-designed leisure experiences can intensify post-consumption behaviours and potentially enhance food well-being.Practical implicationsThe results highlight that integrating customer participation into service design, while also developing opportunities for peer support on-site, can stimulate braggart WoM.Originality/valueExtends burgeoning literature on co-creation and co-design in leisure services. By encouraging active customer participation while providing support and facilitating C2C interactions, service providers can enhance value co-creation, influencing customer experiences and food well-being. Accordingly, the concept of co-created food well-being is introduced.
Understanding the role of users’ socio-location attributes and their privacy implications on social media
Authors: Vgena Katerina , Kitsiou Angeliki , Kalloniatis Christos 
Published: May 2022

Purpose
The purpose of this paper is to establish reciprocity among socio-location attributes while underlining the additional users’ privacy implications on social media (SM).

Design/methodology/approach
Digital identity theories, social software engineering theory and the Privacy Safeguard (PriS) methodology were considered while reviewing 32 papers for identifying users’ SM attributes. After proposing interrelations among socio-location attributes, the PriS method was used to match social aspects of privacy in designing case studies to illustrate the associations through potential users’ privacy implications.

Findings
Eighteen users’ SM attributes were collected and correlated to the Face, Frame, Activity, Time and Stage (FFrATS) 4 W (socio-location attributes), which provoke further privacy implications due to the notions of self-determination and self-disclosure on SM. The authors draw on the PriS methodology to address privacy’s multidimensionality while creating case studies to examine privacy issues arising due to socio-location attribute disclosure and users’ trajectories and normativity lines.

Research limitations/implications
Supplementary case studies and research are needed to enable the design of a socio-spatially and privacy-aware designing methodology.

Practical implications
Designing proper methodologies and techniques to address users’ privacy implications deriving from socio-location attributes can provide designers with a technical solution to SM platforms.

Social implications
Socio-location attribute disclosure constructs representative SM profiles; however, the revelation of attributes and their interrelations create additional privacy implications for SM users.

Originality/value
Deepening the understanding of disclosing socio-location attributes on SM while bridging the socio-technical gap will provide the necessary background for proposing technical solutions to protecting users’ privacy.
Can developmental culture enhance team service innovation? Quantitative and qualitative analyses in the hospitality industry
Authors: Yang Mingjun , Luu Tuan Trong , Qian David 
Published: May 2022

Purpose
Service innovation benefits hospitality organizations’ service quality and competitive advantages. However, how and when team culture amplifies team service innovation is still not fully comprehended. Thus, this study aims to reveal the mediation and moderation mechanisms behind the team-level culture and service innovation nexus.

Design/methodology/approach
This study used both quantitative and qualitative methods to validate the research model. The authors collected data from leaders and their members working in the hospitality sector in China.

Findings
The results demonstrated the positive nexus of developmental culture and team service innovation. This nexus was sequentially mediated by aggregated creative role identity and aggregated creative self-efficacy and was also strengthened by task interdependence.

Practical implications
The results indicated that hospitality practitioners should consistently instill the values of developmental culture into their members to trigger their teams’ service innovative endeavors. They should also design more tasks requiring intensive teamwork and encourage members to complete these tasks collaboratively.

Originality/value
This study advances the understanding of the direct, mediating and moderating effects behind team service innovation.
Understanding the adoption or rejection of management accounting innovations within an SME using Rogers’ conceptual frameworks
Authors: Ben Hamadi Zouhour , Fournès Christine 
Published: May 2022

Purpose
The purpose of this paper is to understand the adoption or rejection of management accounting innovations (MAIs) in the specific context of small and medium entreprises (SMEs) through a constructivist approach of the theory of the diffusion of innovations.

Design/methodology/approach
The paper uses a case study approach during the rollout of two MAIs run by the company’s management controller. One of them was adopted, and the other was rejected. To understand the perception of different actors in the company, the authors carried out 28 semistructured interviews at different periods of time: when the management controller started his job, when he/she was introduced to the two MAIs and at the decision-making to adopt or reject the innovations. The approach of Rogers’ framework is here constructivist. The case study allows us to analyze qualitatively the intrinsic perceived attributes of the innovations as well as the organizational innovativeness and to put them into context.

Findings
MAIs are not merely technical innovations but social practices. The relative advantage is necessary but not sufficient for their adoption. This paper also demonstrates the importance of the champion in the specific context of SMEs. This key player in the promotion and adoption of MAIs in SMEs has to be endorsed by the leader of the organization to ensure the innovation’s adoption. In addition, Rogers’ framework underlines that the predominant factor is complexity as both an endogenous and a heterogeneous element, underscoring the information and training that the project’s promoter should organize for the staff.

Research limitations/implications
The main limit is due to the methodological approach (case study): Would these factors be as significant in a completely different sector to management accounting or in another type of enterprise?

Practical implications
The analytical grid combines different organizational and individual factors described by Rogers and provides us with a predictive approach to the innovation’s chances of adoption and the risk of rejection.

Social implications
Complexity, both as an innovation attribute perceived by individuals and as an internal characteristic of the organization, is a decisive factor in the rejection or adoption decision.

Originality/value
This paper answers to two main research gaps. Most of papers analyze the introduction of one unique innovation in different entities. Here, the authors focus on one entity with two different innovations. In addition, most of papers were retrospective. In this paper, thanks to the case study, the introduction and the process of adoption of two innovations were studied at the time it happened and not after the events had occurred. Moreover, while most papers using Roger’s framework are quantitative, the authors pay attention to the meaning of the different characteristics at different stages and in the specific context of one SME with a constructivist qualitative approach.
Earnings management and tone management: evidence from FTSE 350 companies
Authors: Kayed Salah , Meqbel Rasmi 
Published: May 2022

Purpose
This paper aims to examine whether firms meeting or just beating an earnings benchmark engage in tone management in earnings conference calls to complement earnings management in the UK context. It also investigates whether the audience tone in beating or just meeting earnings fails to predict future performance.

Design/methodology/approach
This study was performed using a sample of non-financial UK firms listed in the FTSE 350 index over the period 2010–2015.

Findings
The findings show that firms that exercise more earnings management to meet or just beat earnings are positively associated with the abnormal tone during earnings conference calls. The outcomes also reveal that the audience’s tone of firms meeting or just beating an earnings benchmark fails to predict future performance. This confirms the effectiveness of the tone management in managing the perception of audience.

Practical implications
This study highlights the need for increased accountability by firms on earnings conference call. It also supports academics and practitioners in understanding the management discretion used in reporting and communication during the earnings conference call. Overall, the results of this study are beneficial for regulators, policymakers and professionals, regarding confirming the need for the earnings conference calls to be regulated.

Originality/value
To the best of the authors’ knowledge, this is the first study that examines the association between earnings management and tone management in the UK earnings conference calls. It adds to the existing literature by examining the self-serving behaviour of managerial tone during earnings conference calls within a sitting in which meeting or just beating a benchmark is used. Unlike several studies that explain the behaviour of tone as a signalling strategy, this study reveals that the tendency of impression management behaviour can explain the tone management.
Can religiosity alter luxury and counterfeit consumption? An empirical study in an emerging market
Authors: Kasber Aya , El-Bassiouny Noha , Hamed Sara 
Published: May 2022

Purpose
The purpose of this study is to describe the effect of religiosity on luxury and counterfeit purchase intentions and to determine the role of consumer ethics in the context of counterfeit purchase intention. The conceptual framework is based on Theory of Planned Behavior (TPB). In the context of counterfeit consumption, religiosity is proposed to be an added component to the theory, while ethical consumption is proposed to mediate the relationship between religiosity and counterfeit purchase intention. In the context of luxury consumption, religiosity is proposed to precede TPB components which then affect luxury purchase intention.

Design/methodology/approach
This is a descriptive study; this study uses a mixed-methods approach, where eight semi-structured in-depth interviews and 500 surveys were conducted and distributed to Egyptian luxury consumers.

Findings
The major results suggest that religiosity and ethical consumption negatively affect counterfeit purchase intention as proposed. The results also reveal that religiosity did not necessitate a negative attitude toward luxury consumption. Religiosity was found to have a positive effect on attitudes, subjective norms and perceived behavioral control. Only subjective norms had significant effect on luxury purchase intention in the research context.

Originality/value
This paper contributes to the TPB by adding religiosity to the theory components as well as integrating the theory of planned behavior with Consumer’s Ethics theory in the context of counterfeit consumption. The study is an attempt to compare between luxury and counterfeit purchase intention while considering the role of individual’s religiosity in these purchases.
Impact of brand familiarity on attitude formation: insights and generalizations from a meta-analysis
Authors: Junior Ladeira Wagner , Santiago Joanna Krywalski , de Oliveira Santini Fernando , Costa Pinto Diego 
Published: May 2022

Purpose
This study aims to investigate the effects of brand familiarity on attitude formation across different advertising channels, product types and brand settings.

Design/methodology/approach
A meta-analysis containing 107 empirical studies with 183 effects sizes tests a theoretical model according to situational moderators and methodological factors of brand familiarity.

Findings
Brand familiarity has stronger positive impacts on attitude formation under particular advertising tools (online and real advertising), product types (hedonic and mature products) and brand characteristics (memory-based recall). The findings also depend on methodological factors such as student samples, laboratory settings and non-estimated effect sizes.

Originality/value
This meta-analytic study reconciles prior inconsistencies and advances the understanding of brand familiarity across key advertising, product and brand moderators.