bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design, synthesis, characterization, catalytic, fluorometric sensing, antimicrobial and antioxidant activities of Schiff base ligand capped AgNPs
Authors: Suneetha G. , Manjari P. Sunitha 
Published: June 2022

Abstract
In recent days, the usage of biological and non-biological pollutants increases and it poses a significant threat to environmental and biological systems. Therefore, the present aim is to develop effective methods to treat such pollutants by using highly stable and small-sized Schiff base ligand capped silver nanoparticles (AgNPs) with a face-centered cubic (fcc) crystalline structure and the size range is 5–10 nm. The potent role of the resulting synthesized AgNPs was found as multiple platforms such as catalyst, sensor, antioxidant, and antimicrobial disinfectant. The synthesized AgNPs were characterized through UV–vis spectroscopy, PL, FTIR, XRD, SEM, and TEM. The FTIR spectrum of AgNPs exhibited the interacted functional groups of Schiff base and size was estimated by XRD and TEM. AgNPs were able to catalytically degrade approximately 95% of methylene blue (MB), rhodamine B (RhB), and eosin Y (EY) dyes within 80 min of reaction time using NaBH4. The fluorometric sensor studies of synthesized AgNPs showed selective sensing of the potentially hazardous Fe2+ ion in water. As an antimicrobial agent, the AgNPs are effective against both Gram-positive and Gram-negative bacteria; as well as fungi, with the zones of clearance as approximately compatible with standard drugs. The AgNPs displayed a greater ability to scavenge free radicals, especially DPPH when compared with AgNPs and ascorbic acid. Thus, the results of this study validate the triple role of AgNPs derived via a simple synthesis as a catalyst, sensor, antioxidant, and antimicrobial agent for effective environmental remediation.
Wheat plant –Plant Growth Promoting Rhizobacteria (PGPR) interaction to alleviate the salt stress in vitro and in vivo
Authors: Omar Nabil , iBRAHIM Nahed , Eltahlawy Yasser , El-Egami Hend , serry Soad , Bishara Mounira 
Published: June 2022

Abstract
Posing a great potential of utilizing Plant Growth promoting Rhizobacteria (PGPR) as a promising alternative to alleviate salinity. Purpose: The aim of the current work is to illustrates the mechanistic basis of PGPRs-triggered salinity tolerance in wheat crops. Methods: Two experiments were conducted at Agricultural Research Center (ARC), 2021-2022, to evaluate the interaction between wheat plant var.Misr1 and two bacterial strains as PGPR namely, Azospirillum brasilense NO40 and Bacillus thuringiensis ( Bt ). One experiment were done in the Laboratory and the second was in the greenhouse. In the laboratory, the staining technique utilizing a spermosphere model was employed in order to detect the colonization efficiency of applied bacteria on wheat seedling roots under sterilized and saline conditions. Results: The date showed the red color of the wheat seedling roots that resulted from the reduction of 2,3,5 triphenyl tetrazolium chloride (TTC) to triphenyl formazan (TPF). Intensity of the red color increased as follow; wheat seedling roots inoculated with mixture of A. brasilense and Bt oculated with A. brasilense that inoculated with Bt . The interaction between wheat seedlings and the PGPR that were used in this work was followed up with transmission electron microscopy (TEM). The greenhouse experiment was conducted on saline soil from Sahl Elhosynia, north of Egypt, to evaluate the effect of these inoculation on growth, photosynthetic pigments and capacity, proline, dry weight of shoots and roots, some antioxidant and rhizosphere enzymatic activities. That data showed increase in all of that parameters in the wheat seedlings that inoculated with mixture of A, brasilense and Bt followed by that inoculated with A. brasilense alone, then by that inoculated with Bt . In conclusion: our bacterial strains that used in this work as inoculums for wheat plants under saline conditions could alleviate the salt stress in wheat saline soils. The mixture of the two strains A. brasilense and Bt gave the best results. Thus, we can apply this Mix in open field experiment to confirm this data.
Locality Sensitive Hashing-aware Fruit Fly Optimization Algorithm and its application in Edge Server Placement
Authors: Cao Qian , Liu Bo , Jin Ying 
Published: June 2022

Abstract
As is well known that global optimization ability of Fruit fly Optimization Algorithm (FOA)is weak because it is easy to fall into local optimum. In this paper a Fruit Fly Optimization Algorithm based on Locality Sensitive Hashing-aware (LSHFOA)was proposed. The locality sensitive hashing mechanism to optimize the generation mechanism for swarm population individuals was used, which can improve the individual diversity of the population. Meanwhile, when the fruit fly population falls into local optimum, the locality sensitive hashing mechanism was adopted to change the population location, which is used for jumping out of local optimal limits. To verify the performance of LSHFOA, it was compared with FOA and its improvement algorithms CFOA, and IFFO with 8 representative benchmark functions. A large number of experimental results showed that LSHFOA has a faster convergence speed and higher precision of optimization for function optimization, especially in high-dimensional multi-peak functions. In the end, we apply this new Algorithm to solve the edge server placement (ESP) problem in the edge computing environment, the experimental results show that the new algorithm has excellent application effect.
Calculation error estimation without assuming a theoretical solution in the numerical calculation of the 1D Poisson equation by IFDM
Authors: Fukuchi Tsugio 
Published: June 2022

Abstract
The extreme high-accuracy calculation of the 1D Poisson equation by the interpolation finite difference method (IFDM) is possible. Numerical calculation errors have conventionally been evaluated by comparison with theoretical solutions. However, it is not always possible to obtain a theoretical solution. In addition, when trying to obtain numerical values from the theoretical solution, the exact numerical value may not be obtained because of inherent difficulties, that is, a theoretical solution equal to the exact numerical solution does not hold. In this paper, we focus on an ordered structure of the error calculated by the high-order accuracy finite difference (FD) scheme. This approach clarifies that in the numerical calculation of the 1D Poisson equation, which is the most basic ordinary differential equation, the error of the numerical calculation can be evaluated without comparison with the theoretical solution. Furthermore, in the numerical calculation by the IFDM, not only the discrete solution but also the continuous approximate solution is defined by piecewise interpolation polynomials.
Enhancing Physical Layer Security via Information Hiding and Chaotic Frequency-Hopping Signal
Authors: Fan MingQuan 
Published: June 2022

Abstract

With the development of super computation ability and invention of quantum computer, the conventional calculation quantity based encryption system suffers great impact. Safeguarding data confidentiality in physical layer of wireless satellite communication system has attracted many eyes from academia and industry. In this paper, we propose a groundbreaking revolution method to enhance physical layer security (PLS) by information hiding technique, that is, embedding secret information into chaotic frequency-hopping signal using MFSK modulation. First, secret information to be transmitted is encrypted with chaotic binary sequence. Secondly, according to frequency-hopping pattern, select suitable modulation order and specific frequency corresponding to each encrypted data block under chaotic address sequence. Finally, the encrypted information is embedded into frequency-hopping Sine signal by MFSK modulation. The experimental results indicate that the proposed scheme is robust against various jamming attacks, such as power attenuation, noise adding, single-tone jamming, key exhaustive search, etc.
Molecular Mimicry Between Tumor Associated Antigens and Microbiota-derived Epitopes
Authors: Ragone Concetta , Manolio Carmen , Mauriello Angela , Cavalluzzo Beatrice , Buonaguro Franco M , Tornesello Maria Lina , Tagliamonte Maria , Buonaguro Luigi 
Published: June 2022

Abstract
Background
The gut microbiota profile is unique for each individual and are composed by different bacteria species according to individual birth-to-infant transitions. In the last years, the local and systemic effects of microbiota on cancer onset, progression and response to treatments, such as immunotherapies, has been extensively described. Here we offer a new perspective, proposing a role for the microbiota based on the molecular mimicry of tumor associated antigens by microbiome-associated antigens.
Methods
In the present study we looked for homology between published TAAs and non-self microbiota-derived epitopes. Blast search for sequence homology was combined with extensive bioinformatics analyses.
Results
Several evidences for homology between TAAs and microbiota-derived antigens have been found. Strikingly, three cases of 100% homology between the paired sequences has been identified. The predicted average affinity to HLA molecules of microbiota-derived antigens is very high (< 100nM). The structural conformation of the microbiota-derived epitopes is, in general, highly similar to the corresponding TAA. In some cases, it is identical and contact areas with both HLA and TCR chains are indistinguishable. Moreover, the spatial conformation of TCR-facing residues can be identical in paired TAA and microbiota-derived epitopes, with exactly the same values of planar as well as dihedral angles.
Conclusions
The data reported in the present study show for the first time the high homology in the linear sequence as well as in structure and conformation between TAAs and peptides derived from microbiota species of the Firmicutes and the Bacteriodetes phyla, which together account for 90% of gut microbiota. Cross-reacting CD8+ T cell responses are very likely induced. Therefore, the anti-microbiota T cell memory may turn out to be an anti-cancer T cell memory, able to control the growth of a cancer developed during the lifetime if the expressed TAA is similar to the microbiota epitope. This may ultimately represent a relevant selective advantage for cancer patients and may lead to a novel preventive anti-cancer vaccine strategy.
Efficacy of two different dosages of prednisolone for treatment of subacute thyroiditis: a single-center, prospective, randomized, open-label, non-inferiority trial
Authors: Xu Yiqi , Liu Shu , Zeng Xiaofan , Wu Qian , Chen Yueping , He Chunling , Zhai Qing , Zhang Binhua , Gao Jialin 
Published: June 2022

Abstract
Background: The aim of study was to explore the efficacy and safety of low-dose(LD) and regular dose(RD) prednisone (PDN) for treatment of subacute thyroiditis (SAT).Methods: Patients were randomly allocated using the block randomization method to the two groups. The primary outcome was the time required for PDN treatment. Secondary outcomes included percentages of relapse, mean score for the Morisky Medication Adherence Scale-8©（MMAS-8）, time required for symptoms to resolve, cumulative PDN dose (mg) and mean erythrocyte sedimentation rate (ESR) at 2 weeks and baseline.Results: The study cohort included 45 patients, randomized 40 participants, and 36 completed the study. There was no significant difference in the treatment duration between the LD and RD groups (48.25±11.42vs.53.30±21.85 days, p=0.379). The mean difference in the time required for PDN treatment between the LD and RD groups was -5.05 (95%CI =-16.61 to 6.51) days, which was within the non-inferiority margin of 7 days. There was a significant difference in the mean score for MMAS-8 between the LD and RD groups (5.94± 0.77vs.5.25±1.12, p=0.037). Also, there was a significant difference in the cumulative PDN dose between the LD and RD groups (447.34±156.74vs.964.75±300.83, p=0.0001).The ESR at 2 weeks was statistically significant as compared to baseline values in both groups, with pre-treatment and post-treatment ESRs of 53.60±26.80 and 18.63±15.00/mm/h, (p<0.0001), in the LD group and 64.20±22.06 and 17.00±8.99/mm/h (p<0.0001) in the RD group.Conclusions: Low-dose PDN therapy may be sufficient to achieve complete recovery and better outcomes of SAT.This study is registered with Chinese Clinical Trial Registry (ChiCTR2100051762).
Approximate Solutions for Nash Differential Games
Authors: Hemeda A. A. , Megahed A. A. , Madkour H. F. A. 
Published: June 2022

Abstract
In this paper, we are concerned with an open-loop Nash differential game. We found the necessary conditions for an open loop Nash equilibrium solution and studied the existence for the solution of the dynamical system of the differential game. Also, we used Picard method to find an approximate solution and the uniform convergence is proved. Finally, we constructed figures for the analysis of the differential game. The results can be applied between economic and financial firms as well as industrial firms.Subject classification: 91A05, 91A10, 91A23, 34A12 and 65L03
The anatomy of the sphenoid sinus and pterygomaxillary junction region in Le Fort I osteotomy
Authors: Ueki Koichiro , Yoshizawa Kunio , Moroi Akinori 
Published: June 2022

Abstract
Purpose.
The purpose of this study was to examine the location and morphology of sphenoid sinus, pterygoid plate and great palatine canal at the pterygomaxillary region in Le Fort I osteotomy.
Method.
The subjects consisted of 144 Japanese patients with jaw deformity patients. Lateral cephalograms and computed tomography (CT) were analyzed for all patients. The measurements of the sphenoid sinus, pterygoid plate and great palatine canal were assessed using 2 bilateral sagittal planes (right and left) involving the great palatine canals and mid-sagittal plane involving ANS and PNS.
Results.
The subjects were divided into three groups (47 class II female, 62 class III female and 35 class III male). Sphenoid sinus existed on the sagittal plane involving the great palatine canal in 81 of 94 sides (86.2%) in class II female, 85 of 124 sides (68.5%) in class III female and 57 of 70 sides (81.4%) male. The distribution was significant difference (P = 0.0386). There was significant difference in the right maxillary sinus length (ML) between class II female and class III female (P = 0.0049). Ramus inclination in cephalometric measurements was selected as a variable related to the vertical distance between the sphenoid sinus wall and PNS (VDS) by stepwise regression analysis (P = 0.003 right, P = 0.0210 left).
Conclusions
. These results suggest that the sphenoid sinus exist more frequently recognized close to superior site of the pterygoid plate in class II female. However, the location of the sphenoid sinus at the pterygomaxillary junction region could not be predicted accurately using cephalometric measurements analysis.
Health Care Personnel’s Perspectives on Human Papillomavirus (HPV) Self-Sampling for Cervical Cancer Screening: A Pre-Implementation, Qualitative Study
Authors: Xiong Serena , Lazovich DeAnn , Hassan Faiza , Ambo Nafisa , Ghebre Rahel , Kulasingam Shalini , Mason Susan , Pratt Rebekah 
Published: June 2022

Abstract
Background: Persistent infection with high-risk human papillomavirus (hrHPV) types are well-documented causes of cervical cancer. Since the implementation of cervical cancer screening methods (e.g., Pap tests), cervical cancer rates have declined. However, Pap tests are still unacceptable to many women and require complex infrastructure and training. Self-sampling techniques for collecting HPV specimens (or “HPV self-sampling”) have been proposed as a possible alternative to overcome these barriers. The objective of this study was to understand various health care personnel’s perspectives on the potential implementation of an HPV self-sampling practice in US primary care settings. Methods: Between May – July 2021, a study invitation was emailed to various health care professional networks across the Midwest, including a snowball sampling of these networks. Eligible participants were invited to a 45-60 minute Zoom-recorded interview session and asked to complete a pre-interview survey. The survey collected sociodemographics on age, occupation, level of educational attainment, race/ethnicity, gender, and an awareness of HPV self-sampling. The semi-structured interview was guided by the Consolidated Framework for Implementation Research and asked participants about their views on HPV self-sampling and its potential implementation. All interviews were audio-recorded, transcribed, and analyzed using NVivo 12. Results: Key informant interviews were conducted with thirty health care professionals - 13 health care providers, 6 clinic staff, and 11 health care leaders - from various health care systems. Most participants had not heard of HPV self-sampling but reported a general enthusiasm for wanting to implement it as an alternative cervical cancer screening tool. Possible barriers to implementation were knowledge of clinical evidence and ease of integration into existing clinic workflows. Potential facilitators included previous adoption of similar self-sampling tools (e.g., stool-based testing kits) and key decision-makers.Conclusion: Although support for HPV self-sampling is growing, its intervention’s characteristics (e.g., advantages, adaptability) and the evidence of its clinical efficacy and feasibility needs to be better disseminated across US primary care settings and its potential adopters. Future research is also needed to support the integration of HPV self-sampling within various delivery modalities (mail-based vs. clinic-based).
Pardosa pseudoannulata mother adopts a compensatory strategy for reproduction deficiency resulting from the suppression of EcR/USP-1-mediated ecdysteroid signaling
Authors: Yang Zhiming , Yan Yangyang , Wu Yong , Yu Na , Liu Zewen 
Published: June 2022

Abstract
Spiders express specific maternal care to their offsprings. The predatory spider Pardosa pseudoannulata mother constructs an eggsac to protect her eggs and juvenile spiderlings. However, here we found that the female spiders ate their eggsacs when ecdysteroid signaling was suppressed. Nuclear receptors (NRs), especially ecdysone receptor (EcR) and ultraspiracle (USP), have attracted extensive attention in arthropods because of their pivotal roles in ecdysteroid signaling cascades. An EcR and two USPs were identified in P. pseudoannulata genome. RNAi against EcR and USP-1 restrained the development of spiderlings, such as delaying moulting and decreasing moulting rate. EcR- and USP-1-silenced adult females produced more invalid eggsacs full of nonviable eggs than the control counterpart, and they ate the invalid eggsacs. EcR and USP-1 responded to the changes of ecdysteroid, and CYP307A1 knockdown led to the similar phenotypes to dsEcR and dsUSP-1 treatments. It proposed that EcR/USP-1-mediated ecdysteroid signaling regulated the development and reproduction in P. pseudoannulata. The period of the first reproduction cycle was 17.87 d in the ecdysteroid signaling-suppressed females, which was 7.19 d shorter than that of the control (25.06 d). The result meant that, when the female spiders detected the nonviable eggs in eggsac, they forwardly ate the invalid eggsac to terminate the useless reproduction cycle and start a new cycle by generating a new eggsac. The strategy can partially compensate for the loss of population growth due to the nonviable eggs, and eating the invalid eggsac also provide a compensation for the physiological consumption during the invalid eggsac care.
The imaging and clinical characteristics of patients with immune breakthrough Omicron-variant infected patients, Tianjin China: Is the vaccine effective?
Authors: Chang Junqi , Wang Li , Yu Zhuo , Ji Xiaodong , Wang Hong , Ge Xihong , Gao Guangfeng , Xia Shuang , Xing Zhiheng , Shen Wen 
Published: June 2022

Abstract
Background
The protective effect of the inactivated vaccine against the omicron variant of COVID-19 is unclear. The purpose of this study was to investigate the protective effect of different vaccination status on omicron infection.
Methods
In this retrospective study, we analyzed patients over 14 years old, and were diagnosed with immune breakthrough Omicron-variant infection between December 2021 and February 2022 in Tianjin, China, as well as data from several previous study infected by other types of SARS-CoV-2. The data were subdivided into three groups: patients with fully, partially and unvaccine. Differences of clinical and imaging characteristics were compared based on the different vaccination status using Pearson Chi-square test, Fisher's accuracy test and non-parametric test. All of the data were also compared with other types of SARS-CoV-2. Logistic regression and mediation effect analysis were used to assess the association between vaccination status and pneumonia progression during hospitalization.
Results
Among the 314 cases of immune breakthrough Omicron-variant infected patients, 21(7%) patients were unvaccinated, 134 (43%) were partially vaccinated, and 159 (50%) were full vaccinated. Among fully vaccinated patients, the proportion of patients with positive CT findings (32%) and CT score 2 (6%) was significantly lower than that of partially vaccinated (46%, 14%) and unvaccinated patients (67%, 19%) (P < 0.05). CT score by vaccination status are similar between Omicron and other types, only partially vaccinated group of Omicron infected patients show lower CT score than other types infected patients (P = 0.005). Increased age and lower IgG levels were associated with the risk of disease progression. IgG level had a complete mediating effect between vaccination status/ days after vaccination and disease progression.
Conclusion
The inactivated vaccine provided similar protection against Omicron infection of SARS-CoV-2, compared to the patients who received other types vaccines. Compared with partially vaccinated and unvaccinated patients, fully vaccinated patients had a higher CT negative rate and a lower rate of severe pneumonia. Vaccination status and days after vaccination affect disease progression through IgG levels.
Rotenone Disrupts Meiotic Maturation via Inhibition of Mitochondrial Function in Porcine Oocytes
Authors: Heo Geun , Sun Ming-Hong , Jiang Wen-Jie , Li Xiao-Han , Lee Song-Hee , Guo Jing , Zhou Dongjie , Cui Xiang-Shun 
Published: June 2022

Abstract
Background: Rotenone is a commonly used insecticidal chemical in agriculture and it is an inhibitor of mitochondrial complex 1. Previous studies have found that rotenone induces the production of reactive oxygen species (ROS) by inhibiting electron transport in the mitochondria of somatic and germ cells. However, there is little precise information on the effects of rotenone exposure in porcine oocytes during in vitro maturation, and the mechanisms underlying these effects have not been determined.Results: First, we found that the maturation rate and expansion of cumulus cells was significantly reduced in the 3 and 5 μM rotenone-treated groups. Further experiments showed that rotenone treatment induced mitochondrial dysfunction and failure of mitochondrial biogenesis by repressing the levels of PGC1-α and SIRT1 during in vitro maturation of porcine oocytes. In addition, rotenone treatment reduced the ratio of active mitochondria to total mitochondria, increased ROS production, and decreased ATP production. The levels of LC3 and active-caspase 3 were significantly increased by rotenone treatment, indicating that mitochondrial dysfunction induced by rotenone increased mitophagy but eventually led to apoptosis.Conclusions: Collectively, these results suggest that rotenone interferes with porcine oocyte maturation by inhibiting mitochondrial function.