bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corpos-manifestos
Authors: Da Silva Lima Fernanda , Delfino das Chagas Maria Eduarda , Da Silva Sousa Leandra 
Published: April 2022

O presente artigo possui como objetivo geral, destacar a atuação das mulheres negras na construção, articulação e sistematização de epistemologias outras desde às margens. O problema de pesquisa consiste em investigar de que forma o feminismo negro pode ser pensado como um projeto político e epistemológico de transformação social a partir dos saberes produzidos pelas mulheres negras no Brasil? Este artigo está estruturado em dois objetivos específicos: (a) estudar a compreensão da dinâmica do poder colonial, que produz e reforça uma desigualdade específica e transversal àquelas concernentes com gênero, raça e classe; e, (b) compreender como as mulheres negras brasileiras reelaboram o discurso e as práticas políticas a partir de epistemologias outras. Evidenciamos que a luta de mulheres negras no Brasil desde a militância popular na contra-narrativa dos movimentos negros e feministas civilizatórios, chegando e universidades na disputa por marcar a si, corpo coletivo, como categoria epistêmica e produtora de conhecimento científico. A pesquisa utiliza o método dedutivo e procedimento monográfico envolvendo pesquisa bibliográfica.
Zachwaszczenie, plonowanie i efektywność ekonomiczna uprawy prosa zwyczajnego (Panicum miliaceum L.) w zależności od rodzaju herbicydów i ich dawki
Authors: Kwiatkowski Cezary A. , Harasim Elżbieta , Klikocka-Wiśniewska Olimpia , Maziarz Piotr 
Published: April 2022

W artykule przedstawiono wyniki badań prowadzonych w Gospodarstwie Doświadczalnym Czesławice (środkowa Lubelszczyzna, Polska) w latach 2014–2016, dotyczące wpływu wybranych herbicydów nalistnych (2,4-D + fluroksypyr; tribenuron-methyl + fluroksypyr; MCPA, dikamba + triasulfuron) na zachwaszczenie, plonowanie i efektywność ekonomiczną uprawy prosa zwyczajnego. Obecnie nie ma zarejestrowanych herbicydów do aplikacji w łanie prosa (w wykazach figurują jedynie herbicydy stosowane przed siewem i przed wschodami prosa). W badaniach uwzględniono herbicydy zalecane do stosowania nalistnego w zasiewach owsa, w dawkach 100% oraz w dawkach pomniejszonych o połowę względem dawek zalecanych. Obiekt kontrolny stanowiły poletka bez aplikacji herbicydów (mechaniczne zwalczanie chwastów). Eksperyment zlokalizowano na glebie płowej wytworzonej z lessu, cechującej się dobrą zasobnością w przyswajalne składniki pokarmowe (II klasa bonitacyjna). Zastosowano klasyczny (płużny) sposób uprawy roli. Przedplonem dla prosa był jęczmień jary. Nawożenie mineralne NPK dostosowano do zasobności gleby. Dowiedziono, że zastosowane herbicydy nalistne (w fazie krzewienia prosa) miały dużą skuteczność chwastobójczą. W efekcie niski stopień zachwaszczenia wpływał na wysoką produkcyjność prosa w porównaniu z uzyskaną w warunkach pielęgnacji mechanicznej (bez herbicydów). Szczególnie pozytywnie oceniono działanie herbicydów 2,4-D + fluroksypyr oraz tribenuron-metyl + fluroksypyr aplikowanych w dawkach 100%. Zastosowanie tych preparatów przyczyniło się do niemal całkowitej eliminacji chwastów. Z kolei herbicyd dikamba + triasulfuron posiadał nieco mniejszą zdolność chwastobójczą. Wykazano zasadność stosowania herbicydów nalistnych w odchwaszczaniu prosa. Ich aplikacja wpływała korzystnie na efekt ekonomiczny uprawy tej rośliny. Największą nadwyżkę bezpośrednią uzyskano stosując pełną dawkę herbicydów Gold 400 EC (2,4-D; fluroksypyr) i Granstar Strong (tribenuron metylowy; fluroksypyr). Pomimo poniesionych większych nakładów na uprawę prosa, koszty preparatów chwastobójczych rekompensowała wysoka wartość uzyskanego plonu.
Complications and outcomes associated with laparoscopic-assisted splenectomy in dogs
Authors: McGaffey Marissa E. S. , Singh Ameet , Buote Nicole J. , Mayhew Philipp D. , Rupnik Nicole , Massari Federico , Case J. Brad , Fransson Boel A. , Oblak Michelle L. , Brisson Brigitte A. , Scott Jacqueline E. , Donovan Victoria A. , Appleby Ryan , Monteith Gabrielle 
Published: April 2022

Abstract

OBJECTIVE
To report the perioperative characteristics and outcomes of dogs undergoing laparoscopic-assisted splenectomy (LAS).

ANIMALS
136 client-owned dogs.

PROCEDURES
Multicentric retrospective study. Medical records of dogs undergoing LAS for treatment of naturally occurring splenic disease from January 1, 2014, to July 31, 2020, were reviewed. History, signalment, physical examination and preoperative diagnostic test results, procedural information, complications, duration of hospitalization, histopathologic diagnosis, and perioperative outcomes were recorded. Perioperative complications were defined using the Veterinary Cooperative Oncology Group – Common Terminology Criteria for Adverse Events (VCOG-CTCAE v2) guidelines.

RESULTS
LAS was performed for treatment of a splenic mass (124/136 [91%]), immune-mediated disease (7/136 [5%]), splenomegaly (4/136 [3%]), or immune-mediated disease in conjunction with a splenic mass (1/136 [1%]). Median splenic mass size was 1.3 cm3/kg body weight. Conversion to open laparotomy occurred in 5.9% (8/136) of dogs. Complications occurred in 78 dogs, with all being grade 2 or lower. Median surgical time was 47 minutes, and median postoperative hospital stay was 28 hours. All but 1 dog survived to discharge, the exception being postoperative death due to a suspected portal vein thrombus.

CLINICAL RELEVANCE
In the dogs of this report, LAS was associated with low rates of major complications, morbidity, and mortality when performed for a variety of splenic pathologies. Minimally invasive surgeons can consider the LAS technique to perform total splenectomy in dogs without hemoabdomen and with spleens with modest-sized splenic masses up to 55.2 cm3/kg, with minimal rates of complications, morbidity, and mortality.
POLA MAKAN, AKTIVITAS FISIK, DAN STATUS GIZI SISWA SMA NEGERI 1 SINGARAJA DI MASA PANDEMI COVID-19
Authors: Kumara Kadek Dhiyo Mamhista , Putra I Wayan Gede Artawan Eka 
Published: April 2022

The policy of learning from home as the effect of pandemic situation can change the diet, physical activity, and the nutritional status of students. This study is an observational study with a cross-sectional design used in SMA Negeri 1 Singaraja with a sample size of 283 students. This study was collecting diet, physical activity, and nutritional status data using an online questionnaire. Data were analyzed descriptively. The results showed that most of the students had a good diet (61,48%), did light physical activity (84,81%), and had normal nutritional status (77,74%). Most students often consume vegetables (>50%), but fruit consumption was still lacking (<10,00%). The consumption of sugary drinks and junk food in adolescents was quite high (>50%). We suggest students to apply a balanced nutritious diet and continue to do physical activity during the pandemic so that they can achieve optimal nutritional and health status.
Keywords: Adolecent, Diet, Physical Activity, Nutritional Status
PENERAPAN PROTOKOL KESEHATAN COVID-19 OLEH REMAJA DI KECAMATAN MENGWI KABUPATEN BADUNG TAHUN 2021
Authors: Pratiwi Ni Ketut Ita , Kardiwinata Made Pasek 
Published: April 2022

The implementation of the health protocol is one of the efforts to break the chain of transmission and reduce the COVID-19 death rate. The low level of implementation of health protocols can lead to violations and risk being vulnerable to COVID-19 transmission. Based on the results of a survey conducted in six regions in Indonesia, 41.30% of violations of the application of the protocol were dominated by teenagers. The purpose of this study was to determine the relationship between sociodemographic characteristics, knowledge and attitudes towards the implementation of the COVID-19 health protocol in Mengwi District, Badung Regency. Quantitative research design with a cross sectional approach on 149 respondents selected by probability sampling, namely multi-stage sampling. The results in this study indicate that most of the adolescents in Mengwi District have implemented health protocols which are categorized as good 75.17%. It was also found that the variables that had a significant relationship to the implementation of the COVID-19 health protocol were age, gender, knowledge and attitudes. While the variables that do not have a significant relationship to the implementation of the COVID-19 health protocol are the level of education, parents' income, and place of residence. The policy makers in Mengwi District are optimizing education, counseling and health promotion to improve the behavior of implementing health protocols as an effort to prevent COVID-19 in adolescents in Mengwi District.
Keywords : Health Protocol, COVID-19, Adolescents , Mengwi
PERBANDINGAN KEPUASAN PASIEN PESERTA JKN DAN NON JKN TERHADAP PELAYANAN RAWAT INAP DI RUMAH SAKIT UMUM PRIMA MEDIKA TAHUN 2020
Authors: Suryaningrat Anak Agung Sagung Istri Maradi , Indrayathi Putu Ayu 
Published: April 2022

The Public Relations Satisfaction Survey of Prima Medika Hospital (RSPM) states that an inpatient feels a difference in hospital staff services when he comes for treatment using the Jaminan Kesehatan Nasional (JKN). This study aims to determine differences in patient satisfaction with inpatient services between JKN and non-JKN patients at the RSPM by using quantitative research methods and case survey data collection methods. The sample survey was conducted in a cross-sectional manner with 96 patient respondents consisting of 48 JKN respondents and 48 non-JKN respondents. The satisfaction questionnaire data includes the dimensions of reliability, responsiveness, competence, accessibility, communication, ethics, credibility, security and completeness. Data were analyzed by univariate and bivariate, then hypothesis testing was carried out with the Mann Whitney U. The mean score of JKN patient satisfaction was 3.29 (quite satisfied) and non-JKN patients 3.73 (quite satisfied). The results of the Mann-Whitney statistical test showed a significant difference in satisfaction (p = 5.0704E-10) between JKN and non-JKN respondents. Significant differences were found in doctor's visite service (p = 2.3144E-7), suitability of prescription drugs (p = 7.0098E-11), ease of obtaining inpatient rooms (p = 9.5274E-15) and information on room availability (p = 4.3919E -13). In general, there are differences in satisfaction, where JKN patient satisfaction average is lower than non-JKN patients.
Keywords: Satisfaction, JKN, Non JKN, Hospital
Analisis Faktor Risiko Pasien Gagal Jantung dengan Reduced Ejection Fraction di RSUD Dr. H. Abdul Moeloek Provinsi Lampung
Authors: Prakasa Rama Agung , Valentina Debby Cinthya D. , Abdiana Riestya , Handayani Riana , BP Nurulando Imansyah 
Published: April 2022

ABSTRACT
Introduction: The number one cause of death for non-communicable diseasesis cardiovascular disease. Congestive heart failure (CHF) is one of the health problems in the cardiovascular systems with increasing incidence every year.
Methods: This study used a retrospective analytic study design using secondary data from patients medical recordsto observethe characteristics of heart failure patients in RSUD Dr. H. Abdul Moeloek Hospital Lampung fromJanuary to June 2018. Data was then processed by using IBM SPSS Statistics v.24.0.
Results : The results of statistical analysis with chi square on risk factors of patients with HFERF showed that age had p-value of 0.85; gender had 0.611and other risk factors such as hypertension, diabetes mellitus (DM), coronary heart disease (CHD) and smoking had p-valuesof 0.113; 0.044; 0.057 and 0.083 respectively. Statistically, the risk factor whichcorrelated to the incidence of HFERF was diabetes mellitus.
Discussion : Patients with DM havegreater risk factor to heart failure. In the Framingham study, it showed that DM independently increases the risk of heart failure bytwo times in men and five times in women. The increased incidence of heart failure in DM also persists despite of other factors like age, hypertension, hypercholesterolemiaand CHD.
Conclusions : DM risk factors significantly related to the high incidence of HFrEF. Gender, age, hypertension, CHD and smoking did not significantly related to the incidence of HFrEF at RSUD Dr. H. Abdul Moeloek. Thisshowedthathe risk factors observed were notsignificantlydifferent from HFrEFandothertypesofheartfailure.
Keywords: ejection fraction, heart failure, risk factor
PERAN TANAMAN SEBAGAI INSEKTISIDA NABATI TERHADAP GIGITAN NYAMUK Aedes aegypt VEKTOR DEMAM BERDARAH DENGUE
Authors: Iqbal Elka Putra Fuad 
Published: April 2022

Introduction: Dengue hemorrhagic fever (DHF) caused by the female dengue virus Aedes aegypt causes nearly 390 million people to be infected each year. the number of dengue cases is increasing from year to year and extraordinary events (KLB) tend to occur every 5 years. Vector mosquito control still uses chemical insecticides, so alternative insecticides such as plant-based insecticides from plants that are cheap, easy to obtain, environmentally friendly and effective in killing adult mosquitoes are needed.
Discussion: Test repelens of some plant extracts are at a dose of 100% which is able to reject mosquito bites above 80% per hour including leaf extracts of Zodia linalol and apinene as mosquito repellent fluids. Tobacco leaf extract is able to resist for 3 hours with the active substances of nicotine and alkaloid tobacco leaves. Gondopuro leaf extract is able to resist for 1 hour containing saponins. Serai Wangi leaf extract can resist for 2 hours because it contains geraniol, citronellol, citronellal, and citral. Clove leaf extract was able to resist for 4 hours as much as 81.7%. Chrysanthemum flower extract was able to resist for 1 hour as much as 89.6%, while suren leaf extract, tuba root and lavender were only able to resist Aedes aegypti mosquito bites below 80%.
Conclusion: Plants can be plant-based insecticides and are proven effective in preventing Aedes aegypt mosquito vector bites

Keywords: Aedes aegypt, dengue hemorrhagic fever, plant insecticide
DEFEK TRABECULAR MESHWORK OLEH MUTASI GEN CYP1B1 PADA PATOGENESIS GLAUKOMA KONGENITAL PRIMER
Authors: Agverianti Theodora , Samosir Renti Kusumaningrum , Theodorus Emeraldha , Valentina Debby Cinthya Damiri 
Published: April 2022

Abstract
Introduction: Primary congenital glaucoma is type of congenital glaucoma that often occurs. The incidence of congenital glaucoma is 1 per 10.000 births. About 65% cases of congenital glaucoma affect men. Congenital glaucoma is associated with an autosomal recessive gene.
Discussion: Congenital glaucoma is glaucoma that occurs in infants or children that occurs due to congenital disorders of aqueous humor flow. This condition is usually progressive and bilateral which has the potential to damage the optic nerve. Early symptoms that can occur are epiphora, which is then followed by photophobia and enlargement of the eyeball or buphthalmos. The most important physical examination that must be done is intraocular pressure examination, visual examination which can be done by fix-and-follow method, and funduscopic examination. The most common cause of congenital glaucoma is a mutation in the CYP1B1 gene. The CYP1B1 gene plays a role in the production of several morphogens that play an important role in the development of trabecular meshwork and other components in aqueous humor secretion. Structural abnormalities caused by mutations in this gene can inhibit fluid drainage resulting in increased intraocular pressure. Another mechanism reported was the CYP1B1 mutation can cause defects in the neural crest.
Conclusion: CYP1B1 gene mutation plays role in the pathophysiology of congenital glaucoma.
TERAPI MESENCHYMAL STEM CELL SEBAGAI MODALITAS TATALAKSANA OSTEOARTRITIS
Authors: Theodorus Emeraldha , Cinthya D Valentina Debby , Agverianti Theodora , Kusumaningrum Samosir Renti 
Published: April 2022

ABSTRACT
MESENCHYMAL STEM CELL THERAPY AS OSTEOARTHRITIS TREATMENT MODALITY
Introduction: Osteoarthritis (OA) is a degenerative and progressive disease with articular cartilage degradation, osteophyte formation, subcondral bone damage, and inflammation of the synovial membrane. The incidence of joint disease aged over 15 years in Indonesia as much as 15%, with 60% is OA in the knee. Recent research mentions the potential for mesechymal stem cell (MSC) as OA treatment.
Discussion: The pathogenesis of OA involves activation of the immune system which causes a decrease in cartilage synthesis and cartilage damage. The immune system also triggers the activation of c-Jun NH 2-terminal Kinase (JNK) signaling pathway which causes cartilage degeneration. OA treatment has evolved into intra-articular therapy, one of which is mesenchymal stem cell (MSC). The mechanism of MSC in OA therapy is to stimulate type two collagen for cartilage regeneration, accelerate cartilage differentiation, and have anti-inflammatory effects. The use of MSC by autotransplantation can be taken through adipose tissue liposuction and bone marrow aspiration. The best use of allotransplantation MSC comes from Wharthon’s Jelly cells from human umbilical cord tissue (HUCT).
Conclusion: Potency of mesechymal stem in cell cartilage’s tissue regeneration process and anti-inflammatory after oxidative stress exposure could be developed as a novel therapy modality to prevent worsening of the disease of patients with OA.
Keywords: Osteoarthritis, Stem cell, Therapy
Kombinasi Nanopartikel Quercetin-Kaempferol Berpolimer Kitosan sebagai Penatalaksanaan Kanker Kolorektal
Authors: Indrakusuma Anak Agung Bagus Putra , Prasetyo Aizar Vesa , Pawestri Nareswara , Sinardja Ketut Adhi Pramana 
Published: April 2022

ABSTRACT
Introduction: Colorectal cancer is a type of cancer, originates in the colon tissue. Colorectal cancer causes 2 million new cases and 1 million deaths globally. The prevalence of colorectal cancer in Indonesia is 12.8% per 100,000 adult population with a 9.5% mortality rate. Current treatment of colorectal cancer are surgery, radiotherapy, and administration of anti-cancer drugs is considered less effective because expensive and its side effects.
Discussion: Quercetin and kaempferol are flavonoids that could manage colorectal cancer through a series of mechanisms at carcinogenesis process stage, blocking proliferation by inhibiting NF-kB, increase apoptosis process by affecting CASP2, CLEC4M, and NTR3K genes, cause antiangiogenesis effects by decreases the expression of MMP-2 and MMP-9. Limitation of this modality is the low bioavailability, therefore it packaged in chitosan polymerized nanoparticles. Quercetin is most obtained from the skin of onions while kaempferol is obtained from leeks. Quercetin-kaempferol chitosan nanoparticles were prepared using the top down method (maceration) and administered orally. Chitosan as a polymer will dissolve when it enters gastric acid. The pharmacokinetics will begin with absorption by small intestine, excretion by kidneys, and elimination by large intestine. Quercetin 15 ?M-30 ?M was able to reduce cell viability to 63 ± 1.3% to 41 ± 0.3%. Meanwhile, kaempferol 30 ?M-60 ?M was able to reduce cell viability to 62 ± 0.83% to 26 ± 0.91%.
Conclusion: Combination of quercetin and kaempferol can increase apoptosis process externally and internally also inhibit proliferation and angiogenesis of colorectal cancer cells.
Keyword: Colorectal cancer, Quercetin, Kaempferol
Efek Skopoletin dari Ekstrak Buah Mengkudu (Morinda Citrifolia) sebagai Modalitas Herbal dalam Penanganan Preeklamsia
Authors: Christopher Michael , Debora Stevina , Louisa Eunike 
Published: April 2022

ABSTRACT
Introduction: Preeclampsia is a disorder which usually occurs in normotensive women and characterized by hypertension. Preeclampsia often causes morbidity and mortality in both mother and fetus. Lots of deaths have been caused by preeclampsia every year. Thus, good and proper treatment need to be done. The aim of this writing is to find out and make a literature review about preeclampsia’s herbal-based treatment which is safe for pregnant women.
Discussion: Many factors take part in the pathogenesis of preeclampsia, including increased oxidative stress and decreased nitric oxide (NO). Increased oxidative stress can cause placental dysfunction which will cause clinical manifestations of preeclampsia. Decreased NO can also cause clinical manifestations of preeclampsia. Scopoletin antioxidant from Morinda citrifolia fruit extract is able to prevent cell damage caused by oxidative stress and prevent inactivation of NO due to free radicals. Scopoletin was proven to significantly decrease blood pressure in rats with oxidative stress-related hypertension (PNL) and to significantly increase NO in the PNL group and the general hypertension group (PN).
Conclusion: Treatment of preeclampsia can be done by scopoletin antioxidant, resulting in the effect on systolic and diastolic blood pressure and mean arterial pressure. Scopoletin also increases NO, resulting in a vasodilation effect. This writing is expected to be a help in advancing the treatment of preeclampsia in the future.
Keywords: Morinda citrifolia, preeclampsia, scopoletin
Pengaruh Probiotik Terhadap Aktivitas Penyembuhan Luka Pada Pasien Dengan Ulkus Kaki Diabetes
Authors: Adnan Muhammad Luthfi 
Published: April 2022

Pendahuluan: Insidensi penyakit diabetes semakin meningkat setiap tahunnya. Salah satu komplikasi terkait pneyakit diabetes adalah ulkus kaki diabetes (UKD). Kejadian ulserasi pada UKD dapat diakibatkan oleh timbulnya infeksi bakteri pada luka. Probiotik merupakan mikroorganisme yang telah lama dimanfaatkan dalam produk makanan karena efek menyehatkannya. Tujuan dari tinjauan ini adalah untuk membahas peran probiotik dalam perbaikan kondisi pasien diabetes mellitus tipe 2 dan pengaruh probiotik dalam proses penyembuhan luka pada luka ulkus kaki diabetes.
Pembahasan: UKD dipengaruhi dari penyakit arteri perifer (PAP) dan neuropati pasien diabetes dengan infeksi bakteri yang terjadi pada luka pasien. Probiotik memiliki efek perbaikan kondisi metabolik pasien diabetes dan meningkatkan kemampuan penyembuhan pasien dengan UKD melalui modulasi pada sistem imun untuk meningkatka kemampuan penyembuhan luka pasien.
Simpulan: Probiotik dapat meningkatkan kemampuan penyembuhan pasien UKD. Penelitian lebih lanjut diperlukan untuk meningkatkan keefektifitas probiotik sebagai terapi penyembuhan pada pasien UKD di masa depan.