bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adherence and retention to the self-managed community-based Step Into Health program in Qatar (2012–2019)
Authors: Chrismas Bryna C. R. , Majed Lina , Al-Mohannadi Abdulla Saeed , Sayegh Suzan 
Published: September 2022

PurposeInvestigate adherence and retention to the “Step Into Health (SIH)” initiative (www.stepintohealth.qa [website access only available from within the State of Qatar]), a Qatari self-managed community-based health program, from 2012 to 2019.MethodsParticipants (16,711; 16–80 years; 37% females, 34% Qatari) used a pedometer or smartphone application (app) to measure step count. Absolute adherence (ADH) and retention (RET) were calculated, with ADH (%) the ratio between number of days data and SIH enrollment length (RET). Linear Mixed Models identified differences in ADH between RET groups, main effects (i.e., sex, device, age, BMI, nationality) and interaction effects for ADH (RET entered as a covariate).ResultsAverage ADH and RET to SIH (irrespective of sex, age, device and BMI) was 50% (±31%), and 16% (±20%), respectively, with ADH differing significantly between RET groups (F = 460.2, p &lt; 0.001). RET (as a covariate) revealed a significant main effect for device (F = 12.00, p &lt; 0.001) and age (F = 4.31, p = 0.001) on ADH observed. There was a significant association between RET and sex (p &lt; 0.001), device (p &lt; 0.001), and age groups 16–25 y (p &lt; 0.001), and 26–35 y (p &lt; 0.001). There were no significant main effects for sex or BMI on ADH, and no interaction effects (p ≥ 0.21) observed.ConclusionsFollow-up data (e.g., interviews, focus groups, etc.) determining why differences in ADH and RET are observed appears prudent. To convert those that lapsed and/or abandoned SIH/PA into committed long-term PA adherers. This would be a first step to develop targeted public health promotions and initiatives to enhance health outcomes at a population level.
The adverse impact of excessive internet use during the COVID-19 pandemic on adolescents' coping skills: A case study in Hanoi, Vietnam 2021
Authors: Bui Quyen Thi Tu , Pham Chi Thi Lan , Le Anh Ha , Pham Duy Quang 
Published: September 2022

IntroductionThe COVID-19 pandemic has created significant stressors in Vietnamese adolescents' lives. Coping skills play important roles in helping adolescents contend with stress. This study aimed to evaluate adolescents' coping skills during the COVID-19 pandemic and examine how those skills are impacted by excessive internet use during this pandemic.MethodsThe study used respondent-driven sampling and Google online survey forms to collect data. The study sample included 5,315 high school students aged 11- 17 years in Hanoi's rural and urban areas. The Kid Coping Scale was applied to examine adolescents' coping, and the coping score was compared among adolescents with different levels of internet use.ResultsThe average coping score measured by Kid Coping Scale was 20.40 (std = 2.13). About half of adolescents often “avoid the problem or the area where it happened” when experiencing a hard time. One-third of adolescents often stopped thinking about the problem they faced. More than one-fourth of respondents stayed online for at least 8 h per day. The online time for learning/other activities showed a reverse dose-response relationship with the coping score; the longer the internet use duration, the lower the coping score.ConclusionThe mean score of coping of Hanoi adolescents was moderate. Internet use has an adverse impact on their coping skills.
Whole-genome sequencing for surveillance of fluoroquinolone resistance in rifampicin-susceptible tuberculosis in a rural district of Shanghai: A 10-year retrospective study
Authors: Zhang Yangyi , Jiang Yuan , Yu Chenlei , Li Jing , Shen Xuhui , Pan Qichao , Shen Xin 
Published: September 2022

BackgroundFluoroquinolones (FQs) are the most important second-line anti-tuberculosis (anti-TB) drugs, primarily used for the treatment of multidrug- or rifampicin-resistant TB (MDR/RR-TB). However, FQs are also commonly used to treat other bacterial infections. There are few published data on the rates of FQ resistance among rifampicin-susceptible TB.MethodsWe used whole-genome sequencing (WGS) to determine the prevalence of FQ resistance among rifampicin-susceptible TB in a rural district of Shanghai. This was a population-based retrospective study of all culture-positive pulmonary TB patients diagnosed in the Chongming district of Shanghai, China during 2009–2018.ResultsThe rate of FQ resistance was 8.4% (29/345) among TB, 6.2% (20/324) among rifampicin-susceptible TB, and 42.9% (9/21) among MDR/RR-TB. Transmission of FQ-resistant strains was defined as strains differing within 12 single-nucleotide polymorphisms (SNPs) based on WGS. Among the rifampicin-susceptible TB, 20% (4/20) of FQ resistance was caused by the transmission of FQ-resistant strains and 45% (9/20) of FQ resistance was identified as hetero-resistance.ConclusionsThe prevalence of FQ resistance in rifampicin-susceptible TB was higher than expected in Shanghai. Both the transmission and the selection of drug-resistant strains drive the emergence of FQ resistance in rifampicin-susceptible TB isolates. Therefore, the WGS-based surveillance system for TB should be urgently established and the clinical awareness of the rational use of FQs for respiratory infections should be enhanced to prevent the premature occurrence of FQ resistance.
Getting acquainted: First steps for child-robot relationship formation
Authors: Ligthart Mike E. U. , Neerincx Mark A. , Hindriks Koen V. 
Published: September 2022

In this article we discuss two studies of children getting acquainted with an autonomous socially assistive robot. The success of the first encounter is key for a sustainable long-term supportive relationship. We provide four validated behavior design elements that enable the robot to robustly get acquainted with the child. The first are five conversational patterns that allow children to comfortably self-disclose to the robot. The second is a reciprocation strategy that enables the robot to adequately respond to the children’s self-disclosures. The third is a ‘how to talk to me’ tutorial. The fourth is a personality profile for the robot that creates more rapport and comfort between the child and the robot. The designs were validated with two user studies (N1 = 30, N2 = 75, 8–11 years. o. children). The results furthermore showed similarities between how children form relationships with people and how children form relationships with robots. Most importantly, self-disclosure, and specifically how intimate the self-disclosures are, is an important predictor for the success of child-robot relationship formation. Speech recognition errors reduces the intimacy and feeling similar to the robot increases the intimacy of self-disclosures.
The feasibility of virtual reality for anatomic training during temporal bone dissection course
Authors: Timonen Tomi , Iso-Mustajärvi Matti , Linder Pia , Vrzakova Hana , Sinkkonen Saku T. , Luukkainen Veera , Laitakari Jaakko , Elomaa Antti-Pekka , Dietz Aarno 
Published: September 2022

Introduction: In recent decades, the lack of educational resources for cadaveric dissections has complicated the hands-on otological surgical training of otorhinolaryngology residents due to the poor availability of cadaver temporal bones, facilities, and limited hours for practice. Since students must gain adequate and patient-safe surgical skills, novel training methods need to be considered. In this proof-of-concept study, a new virtual reality (VR) software is described; this was used during a national temporal bone dissection course where we investigated its feasibility for otological surgical training.Methods: A total of 11 otorhinolaryngology residents attended the annual 2-day hands-on temporal bone dissection course; they were divided into two groups with similar experience levels. Both groups received a lecture on temporal bone anatomy. A total of 22 cadaver temporal bones were harvested for the course; 11 of these bones were imaged by computed tomography. VR software designed for preoperative planning was then used to create 3D models of the imaged temporal bones. Prior to dissection training, the first group underwent a 30-min VR session, where they identified 24 surgically relevant anatomical landmarks on their individual temporal bone. The second group proceeded directly to dissection training. On the second day, the groups were switched. The feasibility of VR training was assessed with three different metrics: surgical performance evaluation using a modified Hopkins objective structured assessment of technical skill (OSATS), time for the surgical exposure of anatomical landmarks, and the user experience collected with a Likert scale questionnaire.Results: No differences were noted in the overall performance between the groups. However, participants with prior VR training had a lower mean time for surgical exposure of anatomical landmarks (antrum 22.09 vs. 27.64 min, p = 0.33; incus 60.00 vs. 76.00, p = 0.03; PSCC 71.83 vs. 88.50, p = 0.17) during dissection training. The participants considered VR beneficial for anatomy teaching, surgery planning, and training.Conclusion: This study demonstrated the feasibility of implementing VR training in a temporal bone dissection course. The VR training demonstrated that even short expert-guided VR sessions are beneficial, and VR training prior to the dissections has a positive effect on the time needed to perform surgical tasks while maintaining comparable performance scores.
A qualitative cross-sectional study exploring the implementation of disability-inclusive WASH policy commitments in Svay Reing and Kampong Chhnang Provinces, Cambodia
Authors: Wilbur Jane , Pheng Pharozin , Has Rithysangharith , Nguon Sophak Kanika , Banks Lena Morgon , Huggett Chelsea , Scherer Nathaniel , Biran Adam 
Published: September 2022

BackgroundThe Government of Cambodia references core concepts of human rights of people with disabilities in their water, sanitation and hygiene (WASH) policies and guidance. However, few references clearly articulate activities to achieve these.MethodsThis cross-sectional study in Cambodia explores the implementation of core concepts of human rights referenced in Cambodia's WASH policies in Kampong Chhnang and Svay Reing Provinces: Individualized services, Entitlement/affordability, Participation, Family resource, Access. Seven government officials and 10 service providers working in Phnom Penh and the two provinces, 16 women and men with disabilities (aged 18–65+), and four caregivers living in the study sites were included. Purposive sampling was applied to select participants. In-depth interviews were conducted via Zoom and over the telephone and analyzed data thematically using Nvivo 12.ResultsThe Three Star Approach for WASH in Schools was noted as a promising approach for implementing policy commitments to make school WASH services accessible. However, policy commitments to disability-inclusive WASH were not always enacted systematically at all levels. Organizations of Persons with Disabilities faced challenges when advocating for disability rights at WASH sector meetings and people with disabilities were inconsistently supported to participate in commune WASH meetings. Poor access to assistive devices (e.g., wheelchair) and inaccessible terrain meant few people with disabilities could leave home and many had inadequate WASH services at home. Few could afford accessible WASH services and most lacked information and knowledge about how to improve WASH access for people with disabilities. Caregivers had no guidance about how to carry out the role and few had assistive devices (e.g., commodes, bedpans) or products (i.e., lifting devices), so supporting WASH for people with disabilities was physically demanding and time-consuming.ConclusionThis study has noted several areas where Cambodia's WASH systems are focusing efforts to ensure people with disabilities gain access to WASH, but it has also highlighted aspects where implementation of policy commitments could be strengthened. A more comprehensive and cross-sectoral approach to progressively realizing the rights to water and sanitation for people with disabilities and challenging disability discrimination more broadly could significantly disrupt the vicious cycle of poverty and disability.
Sublingual misoprostol vs. oral misoprostol solution for induction of labor: A retrospective study
Authors: Amini Mahdi , Wide-Swensson Dag , Herbst Andreas 
Published: September 2022

IntroductionInduction of labor (IOL) is one of the most common obstetrical procedures, with an increasing rate. The prostaglandin E1 analogue misoprostol is frequently used as a primary method of labor induction. The optimal dose and route of administration is yet to be ascertained.AimTo compare efficiacy and safety between a regimen of sublingually administered misoprostol and a regimen of orally administered misoprostol, with cesarean delivery as primary outcome.MethodsA retrospective study was conducted including women carrying a live, singleton fetus in a cephalic position with labor induced at &gt;37 + 0 gestational weeks at Skåne University hospital, Lund, between January 1st 2013 to December 31st 2017. Data was obtained from computerized obstetrical charts.ResultsTotally 2,404 women were included; 974 induced with sublingual misoprostol and 1,430 with oral solution. In primiparous women the cesarean delivery rate was lower in primiparous women induced with oral compared to sublingual misoprostol (20.5% vs. 28.6%, p &lt; 0.001), whereas in parous women the rates did not differ significantly 4.9% vs. 7.5%; NS). The increased risk of caesarean remained after controlling for potential confounding factors (adjusted odds ratio 1.49 (1.14–1.95). Women induced with sublingual misoprostol had a shorter time to vaginal delivery when compared to oral solution (primiparous median 16.7 h vs. 21.7 h; p &lt; 0.001, parous median 9.9 h vs. 13.3 h; p = 0.01), and a higher rate of vaginal delivery within 24 h (primiparas 77.7% vs. 63.3%, p &lt; 0.001, parous 93.2% vs. 84.2%; p = 0.01).ConclusionIOL with oral misoprostol solution was associated with a significantly higher vaginal delivery rate when compared to sublingual misoprostol, whereas sublingual misoprostol was associated with a significantly shorter time from induction to vaginal delivery. Oral administration is considered the most safe and efficient administration of misoprostol, although more studies are needed to find the optimal route and dosage of misoprostol for IOL.
Prediction for 2-year mortality of metastatic ovarian cancer patients based on surveillance, epidemiology, and end results database
Authors: Wang Yongxin , Shan Xue , Dong He , Li Man , Yue Ying 
Published: September 2022

AimTo establish prediction models for 2-year overall survival of ovarian cancer patients with metastasis.MethodsIn total, 4,929 participants from Surveillance, Epidemiology, and End Results (SEER) database were randomly divided into the training set (n = 3,451) and the testing set (n = 1,478). Univariate and multivariable regression were conducted in the training set to identify predictors for 2-year overall survival of metastatic ovarian cancer patients. The C-index was calculated for assessing the performance of the models. The nomogram for the model was plotted. The prediction value of the model was validated in the testing set. Subgroup analysis were performed concerning surgery and chemotherapy status of patients and the metastatic site of ovarian cancer in the testing set. The calibration curves were plotted and the decision curve analysis (DCA) were conducted.ResultsAt the end of follow-up, 2,587 patients were survived and 2,342 patients were dead within 2 years. The 2-year survival rate was 52.5%. The prediction models were constructed based on predictors including age, radiation, surgery and chemotherapy, CA125, and bone, liver, and lung metastasis. The prediction model for 2-year overall survival of ovarian cancer patients with metastasis showed good predictive ability with the C-index of the model of 0.719 (95% CI: 0.706–0.731) in the training set and 0.718 (95% CI: 0.698–0.737) in the testing set. In terms of patients with bone metastasis, the C-index was 0.740 (95% CI: 0.652–0.828) for predicting the 2-year overall survival of ovarian cancer patients. The C-index was 0.836 (95% CI: 0.694–0.979) in patients with brain metastasis, 0.755 (95% CI: 0.721–0.788) in patients with liver metastasis and 0.725 (95% CI: 0.686–0.764) in those with lung metastasis for predicting the 2-year overall survival of ovarian cancer patients.ConclusionThe models showed good predictive performance for 2-year overall survival of metastatic ovarian cancer patients.
Angiosome-directed endovascular intervention and infrapopliteal disease: Intraoperative evaluation of distal hemodynamic changes and foot blood volume of lower extremity
Authors: Wang Chaonan , Chen Junye , Lei Jinsong , Shao Jiang , Lai Zhichao , Li Kang , Cao Wenteng , Liu Xiaolong , Yuan Jinghui , Liu Bao 
Published: September 2022

ObjectivesTo evaluate foot blood volume and hemodynamics and explore whether quantitative techniques can guide revascularization.Materials and methodsA prospective single-center cohort study included thirty-three patients with infrapopliteal artery occlusion who underwent percutaneous transluminal angioplasty (PTA) between November 2016 and May 2020. The time-to-peak (TTP) from color-coded quantitative digital subtraction angiography (CCQ-DSA) and parenchymal blood volume (PBV) were used to evaluate the blood volume and hemodynamic changes in different regions of the foot before and after the operation.ResultsAfter the intervention procedure, the overall blood volume significantly increased from 25.15 ± 21.1 ml/1,000 ml to 72.33 ± 29.3 ml/1,000 ml (p &lt; 0.001, with an average increase of 47.18 ml/1,000 ml. The overall TTP decrease rate, postoperative blood flow time significantly faster than those preoperatively, from 22.93 ± 7.83 to 14.85 ± 5.9 s (p &lt; 0.001, with an average decrease of 8.08 s). Direct revascularization (DR) resulted in significant blood volume improvement than compared with indirect revascularization (IR) [188% (28, 320) vs.51% (10, 110), p = 0.029]. Patients with DR had a significantly faster blood flow time than those with IR [80% (12, 180) vs. 26% (5, 80), p = 0.032]. The ankle-brachial index (ABI) of the affected extremity also showed an significant change from 0.49 ± 0.3 to 0.63 ± 0.24 (p &lt; 0.001) after the intervention. The relative values of ΔTTP and ΔABI showed a weak correlation (r = −0.330).ConclusionsThe quantitative measurement results based on PBV and CCQ-DSA techniques showed that the overall blood volume increased significantly and that the foot distal hemodynamics were significantly improved after endovascular treatment. DR in the ischemic area could r improve foot perfusion.
HUBUNGAN POLA ASUH PEMBERIAN MAKAN DENGAN KEJADIAN STUNTING PADA BALITA DI UPT PUSKESMAS BAHOROK KABUPATEN LANGKAT TAHUN 2021
Authors: Hayati Nila , Helty Mestika Rija 
Published: September 2022

Stunting is a chronic malnutrition problem caused by an inadequate nutritional intake for a long time due to a feeding that is not by nutritional needs. One of the causes of stunting are feeding a parenting. This study aims to find out about the Relationship between Feeding Parenting Patterns with Stunting the incidence in Toddlers at UPT Bahorok Health Center, Langkat Regency in 2021. This research is descriptive correlation research with the cross-sectional approach. This research has been carried out from September 13, 2021, to September 25, 2021. The population is 716 children under five. Sampling using purposive sampling with a sample of 30 people. The results of the study showed that the majority of the Parenting Feeding Patterns at the Bahorok Health Center, Langkat Regency in 2021, and the majority of stunting in toddlers at the Bahorok Health Center, Langkat Regency in 2021 were very short: < -3.0 SD to <-2, 0 SD. Based on the results of the chi-square test, it was found that the p-value = 0.001 <0.05. So it can be concluded that there is a relationship between feeding parenting and stunting in toddlers at UPT Puskesmas Bahorok, Langkat Regency in 2021. Suggestions in this study are UPT Puskesmas Bahorok, Langkat Regency actively pay more attention to children by taking a persuasive approach to mothers by providing information about nutrition to pregnant women to toddlers to avoid stunting.
PENGARUH DOSIS DAN INTERVAL WAKTU PEMBERIAN UNSUR MAKRO KALSIUM (Ca) TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN TOMAT (Solanum lycopersicum L)
Authors: Karim Harli A , M Amir , Iinnaninengseh Iinnaninengseh , Anwar Sarina , Syutriani Syuriani 
Published: September 2022

Abstrak Tanaman Tomat merupakan sayuran penting berfungsi untuk menjaga tubuh dari serangan penyakit, upaya peningkatan produksi tanaman tomat dapat dilakukan dengan penambahan unsur makro yang berperan terhadap perkembangan tanaman. Penelitian ini di laksanakan di Desa Indo Makkombong Kecamatan Matakali Kabupaten Polewali Mandar. Yang dilaksanakan pada bulan Maret 2019 sampai dengan bulan Mei 2019. Pengaruh Dosis dan Interval Waktu Pemberian Unsur Makro Kalsium (Ca) terhadap Pertumbuhan dan Produksi Tanaman Tomat (Solanum lycopersicum L). Penelitian ini dilaksanakan dengan menggunakan Rancangan Acak Kelompok (RAK) dalam bentuk faktorial yang terdiri atas 2 faktor : Faktor pertama dosis pupuk (D) terdiri dari tiga taraf yaitu : takaran pupuk kalsium 50, 100 dan 150 gram/liter air. Faktor kedua interval waktu pemberian pupuk makro kalsium dengan interval waktu 1 kali dalam satu minggu, 1 kali dalam dua minggu dan 1 kali dalam tiga minggu. Dari hasil penelitian dan analisis statistik yang dilakukan dapat diambil kesimpulan sebagai berikut : Interaksi antara dosis dan interval waktu pemberian pupuk kalsium tidak berpengaruh baik terhadap semua parameter pengamatan, Pemberian dosis pupuk kalsium tidak terdapat pengaruh baik terhadap semua parameter pengamatan (D), Interval waktu pemberian pupuk kalsium tidak terdapat pengaruh baik terhadap semua parameter pengamatan (C).
PENGARUH MEDIA TANAM YANG BERBEDA DAN PEMBERIAN DOSIS PUPUK ORGANIK CAIR NASA TERHADAP PERTUMBUHAN DAN HASIL TANAMAN SELADA (Lactuca sativa L.)
Authors: Hasniar Hasniar , Iinnaninengseh Iinnaninengseh , Satriani Satriani 
Published: September 2022

Selada (Lactuca sativa L.) adalah sayuran yang disukai oleh masyarakat, dikomsumsi dalam keadaan mentah atau segar. Penggunaan bahan anorganik yang secara terus menerus mengakibatkan terjadinya residu dan penurunan produksi dan produktivatas tanaman selada, penggunaan media tanam organik dan pupuk organik cair merupakan cara mengatasi permasalahan tersebut. Penelitian ini dilaksanakan di Desa Duampanua, kecamatan Anreapi, Kabupaten Polewali Mandar, Provinsi Sulawesi Barat, dilaksanakan pada Bulan April sampai Juli 2020. Peneltian ini menggunakan rancangan Petak Terpisah (RPT) yang terdiri dari : Petak Utama yaitu Media Tanam yang terdiri dari: tanah + arang sekam + pupuk kandang ayam, tanah + arang sekam + pupuk kandang kambing, tanah + arang sekam + pupuk kandang sapi. Dan Anak Petak pemberian POC Nasa: 0, 2, 4 cc/liter air. Hasil analisis statistik menunjukkan bahwa Penggunan media tanam tanah + arang sekam + pupuk kandang kambing (2:1:1) memberikan pegaruh yang baik pada parameter Berat Basah. Pemberian POC Nasa 2 cc/liter air memberikan pengaruh baik pada parameter jumlah daun. interaksi antar amedia tanam dan pemberian POC Nasa memberikan pengaruh terbaik terhadap parameter Berat Basah.