bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving hypertension control and cardiovascular health: An urgent call to action for nursing
Authors: Hannan Judith A. , Commodore‐Mensah Yvonne , Tokieda Natsuko , Smith Alison P. , Gawlik Kate Sustersic , Murakami Linda , Cooper Jennifer , Koob Susan , Wright Kathy D. , Cassarino Doreen , Arslanian‐Engoren Cynthia , Melnyk Bernadette Mazurek 
Published: February 2022

AbstractBackgroundHypertension is a leading cause of cardiovascular disease (CVD) and affects nearly one in two adults in the United States when defined as a blood pressure of at least 130/80 mm Hg or on antihypertensive medication (Virani et al., 2021, Circulation, 143, e254). Long‐standing disparities in hypertension awareness, treatment, and control among racial and ethnic populations exist in the United States. High‐quality evidence exists for how to prevent and control hypertension and for the role nurses can play in this effort. In response to the 2020 Surgeon General's Call to Action to Control Hypertension, nursing leaders from 11 national organizations identified the critical roles and actions of nursing in improving hypertension control and cardiovascular health, focusing on evidence‐based nursing interventions and available resources.AimsTo develop a unified “Call to Action for Nurses” to improve control of hypertension and cardiovascular health and provide information and resources to execute this call.MethodsThis paper outlines roles that registered nurses, advanced practice nurses, schools of nursing, professional nursing organizations, quality improvement nurses, and nursing researchers can play to control hypertension and prevent CVD in the United States. It describes evidence‐based interventions to improve cardiovascular health and outlines actions to bring hypertension and CVD to the forefront as a national priority for nursing.Linking Evidence to ActionEvidence‐based interventions exist for nurses to lead efforts to prevent and control hypertension, thus preventing much CVD. Nurses can take actions in their communities, their healthcare setting, and their organization to translate these interventions into real‐world practice settings.
Open AR-Sandbox: A haptic interface for geoscience education and outreach
Authors: Wellmann Florian , Virgo Simon , Escallon Daniel , de la Varga Miguel , Jüstel Alexander , Wagner Florian M. , Kowalski Julia , Zhao Hu , Fehling Robin , Chen Qian 
Published: February 2022

Abstract
Virtual reality concepts have been widely adapted to teach geoscientific content, most notably in virtual field trips—with increased developments due to recent travel restrictions and challenges of field access. On the spectrum between real and fully virtual environments are also combinations of digital and real content in mixed-reality environments. In this category, augmented-reality (AR) sandboxes have been used as a valuable tool for science outreach and teaching due to their intuitive and haptic interaction-enhancing operation. Most of the common AR-sandboxes are limited to the visualization of topography with contour lines and colors, as well as water simulations on the digital terrain surface. We show here how we can get beyond this limitation, through an open-source implementation of an AR-sandbox system with a versatile interface written in the free and cross-platform programming language Python. This implementation allows for creative and novel applications in geosciences education and outreach in general. With a link to a 3-D geomodelling system, we show how we can display geologic subsurface information such as the outcropping lithology, creating an interactive geological map for structural geology classes. The relations of subsurface structures, topography, and outcrop can be explored in a playful and comprehensible way. Additional examples include the visualizations of geophysical fields and the propagation of seismic waves, as well as simulations of Earth surface processes. We further extended the functionality with ArUco-marker detection to enable more precise and flexible interaction with the projected content. In combination, with these developments, we aim to make AR-sandbox systems, with the additional dimension of haptic interactions, accessible to a wider range of geoscientific applications for education and outreach.
Exploring the impact of pulse oximeter selection within the COVID-19 home-use pulse oximetry pathways
Authors: Stell David , Noble Jonathan James , Kay Rebecca Hazell , Kwong Man Ting , Jeffryes Michael John Russell , Johnston Liam , Glover Guy , Akinluyi Emmanuel 
Published: February 2022

BackgroundDuring the COVID-19 pandemic, portable pulse oximeters were issued to some patients to permit home monitoring and alleviate pressure on inpatient wards. Concerns were raised about the accuracy of these devices in some patient groups. This study was conducted in response to these concerns.ObjectivesTo evaluate the performance characteristics of five portable pulse oximeters and their suitability for deployment on home-use pulse oximetry pathways created during the COVID-19 pandemic. This study considered the effects of different device models and patient characteristics on pulse oximeter accuracy, false negative and false positive rate.MethodsA total of 915 oxygen saturation (spO2) measurements, paired with measurements from a hospital-standard pulse oximeter, were taken from 50 patients recruited from respiratory wards and the intensive care unit at an acute hospital in London. The effects of device model and several patient characteristics on bias, false negative and false positive likelihood were evaluated using multiple regression analyses.Results and conclusionsAll five portable pulse oximeters appeared to outperform the standard to which they were manufactured. Device model, patient spO2and patient skin colour were significant predictors of measurement bias, false positive and false negative rate, with some variation between models. The false positive and false negative rates were 11.2% and 24.5%, respectively, with substantial variation between models.
Coupled micromechanical resonator for mass detection
Authors: Yu Hong , Wang Min , Mao Shihan , Chen Ying , Lei Shuangying 
Published: February 2022

A resonator composed of two coupled doubly-clamped beams is fabricated and used as a mass sensor. Five mass blocks made of IP-L780 photoresist are printed on each resonator beam by 3D microprinting technology as mass loading. The minimum mass which the sensor can detect is as low as 10 ng. The experimental results show that the asymmetric resonant mode of this resonator has a higher Q factor than the symmetric mode when doing mass detection. The responsivity of the coupled resonator for the mass sensing reaches 58.5 Hz/ng.
Disruption of DNA Repair and Survival Pathways through Heat Shock Protein Inhibition by Onalespib to Sensitize Malignant Gliomas to Chemoradiation Therapy
Authors: Xu Jihong , Wu Pei-Jung , Lai Tzung-Huei , Sharma Pratibha , Canella Alessandro , Welker Alessandra M. , Beattie Christine E. , Elder J. Brad , Easley Michelle , Lonser Russell , Jacob Naduparambil K. , Pietrzak Maciej , Timmers Cynthia M. , Lang Frederick , Sampath Deepa , Puduvalli Vinay K. 
Published: February 2022

Abstract

Purpose:
Proficient DNA repair by homologous recombination (HR) facilitates resistance to chemoradiation in glioma stem cells (GSC). We evaluated whether compromising HR by targeting HSP90, a molecular chaperone required for the function of key HR proteins, using onalespib, a long-acting, brain-penetrant HSP90 inhibitor, would sensitize high-grade gliomas to chemoradiation in vitro and in vivo.

Experimental Design:
The ability of onalespib to deplete HR client proteins, impair HR repair capacity, and sensitize glioblastoma (GBM) to chemoradiation was evaluated in vitro in GSCs, and in vivo using zebrafish and mouse intracranial glioma xenograft models. The effects of HSP90 inhibition on the transcriptome and cytoplasmic proteins was assessed in GSCs and in ex vivo organotypic human glioma slice cultures.

Results:
Treatment with onalespib depleted CHK1 and RAD51, two key proteins of the HR pathway, and attenuated HR repair, sensitizing GSCs to the combination of radiation and temozolomide (TMZ). HSP90 inhibition reprogrammed the transcriptome of GSCs and broadly altered expression of cytoplasmic proteins including known and novel client proteins relevant to GSCs. The combination of onalespib with radiation and TMZ extended survival in a zebrafish and a mouse xenograft model of GBM compared with the standard of care (radiation and TMZ) or onalespib with radiation.

Conclusions:
The results of this study demonstrate that targeting HR by HSP90 inhibition sensitizes GSCs to radiation and chemotherapy and extends survival in zebrafish and mouse intracranial models of GBM. These results provide a preclinical rationale for assessment of HSP90 inhibitors in combination with chemoradiation in patients with GBM.
Nuestros años Lefort. Notas sobre la recepción de Claude Lefort en la argentina de la transición a la democracia
Authors: Hilb Claudia 
Published: February 2022

Esta breve presentación no tiene mucha mayor pretensión que la de constituir un homenaje a Claude Lefort, quien sin duda alguna marcó de manera absolutamente determinante mi trayectoria intelectual, y la de algunos pocos otros colegas en Argentina, a partir de principios de la década del ’80. Mi propósito se limita a reseñar de qué manera se produjo la recepción de la obra de Lefort en Argentina en esa década, quiénes, en qué condiciones, desde qué cruces o intereses, empezaron a leerlo, a prestarle atención, a pensar con él, o contra él, o a través de él, y lo incluyeron explícitamente o no tanto en sus textos, en sus referencias, en sus clases.
Responsive strategies of three sympatric small rodents to the altitudinal effects on microhabitats
Authors: Lee Jae-Kang , Eom Tae-Kyung , Bae Ho-Kyoung , Lee Dong-Ho , Rhim Shin-Jae 
Published: February 2022

Abstract
This study evaluated the effects of altitudinal gradients on small-rodent populations and microhabitat conditions. We selected three altitudinal bands: lowland, mid-land, and highland. We captured three small-rodent species, the striped field mouse (Apodemus agrarius), the Korean field mouse (A. peninsulae), and the red-backed vole (Myodes regulus). A. agrarius preferred microhabitats with dense ground vegetation and sparse mid-story vegetation, basal area, downed trees, and stone coverage. A. peninsulae utilized ground vegetation, overstory vegetation, and downed trees. M. regulus occupied microhabitats with abundant stone coverage and little ground vegetation coverage. Ground vegetation coverage was higher in the mid-land. The lowland was characterized by high understory vegetation, bulky downed trees, and high stone coverage. A. agrarius mostly occupied the mid-land, whereas A. peninsulae and M. regulus mainly inhabited the lowland. Our results show that each small-rodent species had its own strategy for utilizing the key habitat factors in altitudinally affected microhabitats and for reducing competition among the populations. This finding contributes to improving knowledge of the ecological altitudinal features of microhabitat conditions, as well as the altitudinal distributions and abundances of three small-rodent species.
Amplitude of the daily pattern of rest – activity in different species of Leopardus kept in captivity
Authors: Giannetto Claudia , Cerutti Raul Delmar , Scaglione Maria Cristina , Sciabarrasi Antonio Alejandro , Pennisi Melissa , Piccione Giuseppe 
Published: February 2022

Abstract
Closer examination of the diurnal or nocturnal nature of wildlife species improves the knowledge necessary for landscape identity and biodiversity preservation. The aim of this study was to evaluate the daily rhythmicity of total locomotor activity in wild felids of several species of Leopardus of similar body weight housed in captivity: Geoffroy’s cat (Leopardus geoffroyi), ocelot (Leopardus pardalis), oncilla (Leopardus tigrinus) and margay (Leopardus wiedii). Twenty-four felids, six animals for each species, were housed under a natural light/dark cycle. The activity was recorded for thirteen consecutive days by means of an actimeter attached to a neck collar. Using cosinor rhythmometry, circadian rhythmic parameters (mesor, amplitude and acrophase) were assessed and compared among the several species. The daily and individual chronobiological variations of rest and activity showed a well-defined pattern. A nocturnal daily rhythmicity of locomotor activity was observed in Geoffroy’s cat, ocelot, oncilla and margay. The acrophase was observed shortly after midnight in margay and Geoffroy’s cat, and early at night in oncilla and ocelot. Our results improve the knowledge about the circadian system in wild animals. They can be a contribution to understanding the adaptive behaviour of wild felid species kept in zoological parks and rehabilitation agencies in providing the proper care for these animals
The Role of Technology in Increasing Competitiveness: An Examination of the Indian Garment Clusters
Authors: Ray Saon , Miglani Smita 
Published: February 2022

In this article, we examine the Indian garment industry to examine the effect of clusters on the sales of this industry. The data has been collected through a primary survey in five garments clusters in India. The variable that is significant in explaining sales in most equations is technology proxied by imported machinery. It has been argued that inter-firm linkages and linkages between firms, service providers and institutions are crucial for competitiveness and this is best achieved through a cluster. Studies on clusters have shown that some clusters have been able to deepen their inter-firm division of labour, raise their competitiveness and break into international markets. The development of the cluster in India has followed the ‘top-down’ approach and the natural process through which linkages are developed are yet to occur in most clusters. JEL Codes: F14, L67, L23
Clinical Outcomes of Adults With Diagnosed HIV Living in Ending the HIV Epidemic Priority Areas, Medical Monitoring Project, 2018
Authors: Chowdhury Pranesh P. , Beer Linda , Crim Stacy M. , Bosh Karin A. , Desamu-Thorpe Rodel G. , Shouse Luke R. 
Published: February 2022

Objectives: The Ending the HIV Epidemic (EHE) initiative prioritizes treatment and prevention efforts in counties where most new HIV diagnoses occur and states with substantial incidence of new HIV diagnoses in rural areas. Understanding the characteristics of adults with HIV living in EHE priority areas, and how these characteristics compare with adults with HIV living in non–EHE priority areas, can inform EHE efforts. Methods: We analyzed data from the 2018 Medical Monitoring Project (MMP) to understand the characteristics of adults with HIV living in 36 of 48 EHE priority counties; San Juan, Puerto Rico; and 1 of 7 EHE priority states. We calculated weighted percentages of sociodemographic characteristics, behaviors, and clinical outcomes of adults with diagnosed HIV living in MMP EHE priority areas and compared them with characteristics of adults who did not live in MMP EHE priority areas using prevalence ratios (PRs) with predicted marginal means. Results: Living in an MMP EHE priority area was more common among adults who were non-Hispanic Black or Hispanic, experienced homelessness, or were food insecure compared with adults who were non-Hispanic White (59.3% and 58.4% vs 41.0%), not experiencing homelessness (60.9% vs 51.9%), or not food insecure (59.8% vs 51.0%). Adults who lived in MMP EHE priority areas were significantly less likely to be adherent to their HIV medications (PR = 0.95; 95% CI, 0.91-0.99) and durably virally suppressed (PR = 0.94; 95% CI, 0.91-0.97), and more likely to miss scheduled appointments for HIV care (PR = 1.31; 95% CI, 1.10-1.56) than adults who did not live in MMP EHE priority areas. Conclusion: To increase viral suppression and reduce HIV transmission, it is essential to strengthen public health efforts to improve medication and appointment adherence in this population.
Teachers as Grantseekers: The Privatization of the Urban Public School Teacher
Authors: Freedman Sara 
Published: February 2022

This article explores the impact of grantseeking on urban public school teachers. It first analyzes how grantseeking, primarily but not exclusively promoted by numerous private and corporate foundations, has introduced urban teachers to and fostered among them some of the central tenets of the movement to privatize education—to “market” one's teaching as a product and oneself as a valuable commodity; to embrace competition and the creation of self-selected communities; and to replace a commitment to a broad-based democracy in which the needs of all are met with fulfilling the needs of the “deserving” few.The article next discusses the ways in which specific assumptions about urban teachers have influenced the development of such grant competitions. It also discusses the ways these assumptions promote the ability of a very limited number of high status urban teachers to successfully compete in such competitions while working to exclude others, particularly teachers of color and those whose native language is not English.The article then presents a case history of one grantseeker to illustrate the contradictory effects of teachers’ participation in privately funded grant programs. It ends by raising questions about the purpose and effect of grantseeking in education and its potential role in changing the dominant means of educating children in the United States from a public school system subject to community wide support and governance—in theory if not in practice—to an increasingly privatized one.
“Open Education” Revisited: Promise and Problems in American Educational Reform (1967–1976)
Authors: Smith Lydia A. H. 
Published: February 2022

Between 1967 and 1976, that period of social/political protest and reform, the ideas and practices of “open education” spread rapidly across this country. Educators were caught up in a kind of education that seemed to answer the many strident criticisms of American public schools. News of successful English informal schools fanned the flames. It was a time of excitement, progress, and optimism that schools could make a positive difference in the lives of children, contribute to the search for alternatives to existing social institutions, and promote the liberation of the human mind and spirit, so long desired and so seldom achieved. This informal, nontraditional style of education seemed to promise much, but it brought serious problems with it because it would require fundamental changes, both in institutional practices and policies and in basic assumptions about children, teaching and learning, and the role of schools in the American society. Support was gradually withdrawn and America went “bask to basics.” However, contemporary educational research seems now to bear out the basic notion of the open classroom, namely, that children can and should be taught in the ways they learn best. It is time for another look at “open education.”
Clinical Outcomes in Patients With Humeral Avulsion Glenohumeral Ligament Lesions in the Setting of Anterior Shoulder Instability: A Retrospective Comparative Study
Authors: Davey Martin S. , Hurley Eoghan T. , Gaafar Mohamed , Delaney Ruth , Mullett Hannan 
Published: February 2022

Background: Humeral avulsion glenohumeral ligament (HAGL) lesions are often underreported but have been shown to occur in up to 10% of cases of anterior shoulder instability. Purpose: To compare clinical outcomes and recurrence rates of patients with HAGL lesions undergoing open stabilization for anterior shoulder instability versus a pair-matched control. Study Design: Cohort study; Level of evidence, 3. Methods: A retrospective review of all patients who underwent both arthroscopic and open stabilization procedures with a minimum 24-month follow-up was performed. Patients with HAGL lesions were pair-matched in a 1:6 ratio for age, sex, sport, level of preoperative play, and follow-up length with those without HAGL lesions who underwent arthroscopic Bankart repair alone. Return to play (RTP), the level of return, and the timing of return were assessed. In addition, recurrence, visual analog scale for pain (VAS), Subjective Shoulder Value (SSV), Rowe score, satisfaction, and whether they would undergo the same surgery again were compared. Results: A total of 15 patients with HAGL lesions who underwent shoulder stabilization procedures were included, with a mean age of 21.5 ± 4.1 years and mean follow-up of 53.5 ± 17.4 months, and were pair-matched to 90 patients without HAGL lesions. Overall, there was no significant difference in any of the clinical outcome scores (VAS, Rowe, SSV, satisfaction) used between the 2 groups (1.6 vs 1.7, P = .86; 83.4 vs 88.0, P = .06; 85.7 vs 87.2, P = .76; and 86.7% vs 94.5%, P = .26, respectively). In addition, there were no significant differences in terms of overall rates, levels, and timing of RTP between the 2 groups (93.3% vs 90.0%, P > .99; 80.0% vs 78.9%, P > .99; and 5.3 ± 2.2 vs 5.9 ± 2.9 months, P = .45, respectively). There was no significant difference in the rates of apprehension, subluxation, and recurrent instability between the HAGL and pair-matched control groups (26.7% vs 26.7%, P > .99; 6.7% vs 3.3%, P = .47; and 13.3% vs 6.7% months, P = .32, respectively). Conclusion: Patients with anterior shoulder instability undergoing surgical stabilization with open HAGL repair demonstrate excellent functional outcomes and high rates of RTP, with low rates of recurrence in the medium term compared with a control group without HAGL lesions who underwent arthroscopic Bankart repair alone.
The Association Between Maternal Employment and Breastfeeding Duration With Household Income in Mexico
Authors: Campos Ana Paola , Hawkins Summer Sherburne 
Published: February 2022

Background: Breastfeeding offers the best nutrition during the first months of life. Scholars have identified a dose-response association between breastfeeding duration and reduced risk for child morbidity and mortality. In upper-middle-income countries, including Mexico, maternal employment has been negatively associated with breastfeeding duration. Despite increasing numbers of women entering the workforce and disproportionately participating in the informal sector, where they are un-entitled to paid maternity leave, little is known about how these factors may affect breastfeeding practices. Research Aim: To determine whether household income moderated the association between maternal employment status (defined as unemployed, formal, and informal full- and part-time employed) and any breastfeeding for ≥ 6 months. Methods: We conducted a cross-sectional study using retrospective secondary data from the 2018–2019 Mexican Health and Nutrition Survey. The analytic sample included data about 2,156 children aged 6–36 months. We computed logistic regression models stratified by household income. Results: The association between maternal employment and breastfeeding duration varied by household income. Compared to unemployed women, among lower-income households, children were less likely to be breastfed for ≥ 6 months when the participants was part-time informally employed ( AOR = 0.30, 95% CI [0.13, 0.69]). Among higher-income households, children were less likely to be breastfed for ≥ 6 months when the participants was full-time formally employed ( AOR = 0.52, 95% CI [0.30, 0.88]). Conclusions: To increase breastfeeding duration, stakeholders need to continue strengthening and enforcing policies among formally employed women, and strategies are urgently needed to support women in the informal sector, particularly those in lower-income households.