bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards the attainment of climate-smart PPP infrastructure projects: A critical review and recommendations
Authors: Akomea-Frimpong Isaac , Agyekum Amma Kyewaa , Amoakwa Alexander Baah , Babon-Ayeng Prosper , Pariafsai Fatemeh 
Published: October 2022

Abstract

Extreme climate change is an existential threat to humanity and infrastructure development. At the same time, the construction and operation of carbon-intense public-private partnership (PPP) infrastructure such as road transport, water, public houses, energy supply and saniation unleash most of the greenhouse gas emissions that impacts negatively on the climate. Increasingly, there is a heightened interests in the development and financing of climate-smart PPP solutions to save our planet from climate disaster. Therefore, in this present study, a critical review to identify the key driving factors and challenges for climate-smart PPP solutions was undertaken together with recommendations. The paper utilised a systematic literature review (SLR) method where data was sourced from prominent academic databases of Scopus, Web of Science, Google Scholar, and PubMed. The outcomes of the review demonstrate key drivers such as the urgent need to attain net-zero carbon emission targets and climate activisim to transition to low-carbon public infrastructures. The barriers identified include poor responses to resolving climate crisis in the PPP infrastructures, and lapses in project policies and practices to achieve climate-resilient PPPs. The results of this article highlight relevant gaps and recommendations for further research and management of PPP projects.
Simultaneously evaluation of physiological and biochemical responses in the leaves and roots of common Iranian bermudagrass [Cynodon dactylon L. (Pers.)] accessions that can tolerate a wide range of temperature fluctuations
Authors: Amini Zohreh , Salehi Hassan , Chehrazi Mehrangiz , Etemadi Mohammad 
Published: October 2022

AbstractThe average temperature of the earth's surface is increasing swiftly, negatively affecting the urban space's green cover. Using local genetic variation based on retrieving native populations has been proposed as a useful option to deal with global warming and preserve turfgrass quality. In this study, to identify Iranian common bermudagrass [Cynodon dactylonL. (Pres.)] accessions which could endure a wide range of temperature fluctuations, eight Iranian accessions of common bermudagrass were collected from eight provinces with different climatic conditions including Taft, Naein, Malayer, Gardane-Heyran, Safashahr, Gorgan (as cold tolerant accessions) and Ahvaz (as a native accession to tropical regions) along with a foreign cultivar (California origin named Blackjack). They were subjected to five temperature regimes, including 35/30°C, 40/35°C, 45/40°C, 50/45°C, and 50/50° day/night cycles for 21 days. Evaluation of physiological parameters (total chlorophyll, leaf relative water content, electrolyte leakage, root viability and total soluble proteins), osmolytes (proline, total soluble carbohydrates and starch), antioxidants (superoxide dismutase, ascorbic peroxidase, catalase, and peroxidase enzymes) in the leaves and roots simultaneously revealed that among investigated accessions Gorgan with low electrolyte leakage in leaves and starch storage in roots and high Tchl, RWC, antioxidant enzymes activity and total soluble carbohydrates in leaves and roots could endure the harsh conditions of the 50/45°C temperature regime with acceptable turfgrass quality. Gorgan can endure almost 65°C temperature fluctuations and could be introduced as a cold- and heat-stress tolerant accession. These findings provided that a heat tolerant plant with controlling respiratory rate in roots and efficiently breaking down starch storage to carbohydrates could provide the energy required for whole plant metabolic activities. This experiment also highlights the importance of simultaneously investigating evaluated parameters in leaves and roots.
Power Quality Enhancement based on Type 2 Fuzzy logic direct power control of a Microgrid connected photovoltaic system with battery storage feeding nonlinear load
Authors: Bouziane Maroua , Zarour Laid , Mehazzem Fateh 
Published: October 2022

Abstract
In this paper, we deal with control performance and power qualityimprovement of Microgrid connected Photovoltaic System (PVS) withstorage. A comparative study was conducted between two versions of Fuzzy Logic Controllers: Type 1 (T1FLC) and Type 2 (T2FLC). DCside of the proposed microgrid system is composed of a photovoltaic systemand battery storage. Both are controlled by fuzzy logic algorithmsto extract maximum power from solar panels, and guarantee optimalmanagement of battery storage. AC side is composed of a two-level MultifunctionalVoltage Source Inverter (MVSI) associated with a ShuntActive Power Filter (SAPF) connected to the grid and supplies a nonlinearload. This side is controlled by a Direct Power Control strategyassociated with Space Vector-Modulation technique (DPC-SVM),and an Fuzzy Logic Controller (FLC) algorithm to inject the extractedactive power into the network and compensate the reactive power.The growing integration of Renewable Energy Sources (RES) poses several challenges to Microgrid systems. The T2FLC structureis proposed to better handle those challenges and enhance performance.Simulation of the proposed solution is validated under MATLAB/Simulink. The obtained simulation results show that T2FLC technique provides the best solution in terms of good tracking andoptimization performance, reactive power compensation, Total HarmonicDistortion (THD) elimination caused by non-linear loads,and robustness against irradiance and nonlinear load variations.
Reduced order homogenization of thermoelastic materials with strong temperature-dependence and comparison to a machine-learned model
Authors: Sharba Shadi , Herb Julius , Fritzen Felix 
Published: October 2022

Abstract
In this work, an approach for strongly temperature-dependent thermoelastic homogenization is presented. It is based on computational homogenization paired with reduced order models (ROM) that allow for full temperature dependence of material parameters in all phases. In order to keep the model accurate and computationally efficient at the same time, we suggest the use of different ROMs at few discrete temperatures. Then, for intermediate temperatures, we derive an energy optimal basis emerging from the available ones. The reduced homogenization problem can then be solved in real-time.
Other than in classical homogenization where only the effective behavior, i.e. the effective stiffness and the effective thermal expansion, of the microscopic reference volume element (RVE) are of interest, our ROM delivers also accurate full-field reconstructions of all mechanical fields on the RVE scale.
We show that the proposed method referred to as optimal field interpolation is on par with linear interpolation in terms of its numerical cost but with an accuracy that matches direct numerical simulation (DNS) in many cases, i.e. very accurate real-time predictions are anticipated with minimal DNS inputs that range from two to six temperatures at which simulations are pursued. Further, we pick up a black box machine-learned model as an alternative route and show its limitations in view of the limited training data.
Long-term observation of monovision surgery using femtosecond laser- assisted laser in situ keratomileusis for myopia correction in early presbyopia
Authors: Ye Yuhao , Zhang Zhe , Niu Lingling , Shi Wanru , Lu Zhong-Lin , Zhao Jing , Zhou Xingtao 
Published: October 2022

Abstract
Purpose: This study aimed to investigate the long-term safety and efficacy of femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) in patients with myopia with presbyopia.
Methods: This case series study included 30 eyes of 15 patients who underwent monovision designed FS-AISK for myopia correction with presbyopia (male/female, 8/7; age, 49.20±7.05 years; spherical equivalent [SE], –6.97±1.82 D). Parameters including SE; uncorrected distal visual acuity (VA); corrected distal VA; intraocular pressure; presbyopic add power; VA of dominant eyes (D-eye), non-dominant (nD-eye) eyes, and both eyes (Bi) at 0.4 m, 0.8 m, and 5 m; wavefront aberration; and contrast sensitivity (CS) were recorded. Follow-up was performed for 2.5 years. Differences were considered statistically significant at p<0.05.
Results: The safety indicesand efficacy indices were 1.08±0.19 and 0.77±0.29 at 2.5 years postoperatively. The VAs (logMAR) of D-eyes, nD-eyes, and Bi at 5.0 m, 0.8 m, and 0.4 m were –0.02±0.08, 0.26±0.19 (D-eyes vs. nD-eyes, p<0.01), and –0.29±0.06; 0.05±0.14, 0.02±0.11 (D-eyes vs. nD-eyes, p>0.05), and –0.03±0.07; and 0.21±0.17, 0.01±0.07 (D-eyes vs. nD-eyes, p<0.001), and –0.02±0.07, respectively. The binocular VA was >20/25 (Snellen lines) at three distances in 100% of the subjects. Between the D-eyes and nD-eyes in CS, a minor but significant difference was observed at 1.5–12.0 cpd.
Conclusions: FS-LASIK is safe and practical for the correction of myopes with presbyopia, with long-term efficacy at near and far distances. Compared with D-eyes, the CS in nD-eyes may be impaired at low and moderate spatial frequencies.
Association between sleep duration and depressive symptoms in Chinese aged 45 years and older: an empirical study based on 2018CHARLS
Authors: Du Jin , Yuan Mei , Ma Guifeng , Ma Anning 
Published: October 2022

Abstract
Background The relationship between sleep time and depressive symptoms in middle-aged and elderly people has not been fully revealed, and there are few empirical studies from China. Objective An empirical study was conducted based on 2018CHARLS to explore the association between sleep duration and depressive symptoms in middle-aged and elderly people. Methods A total of 17293 middle-aged and elderly people aged ≥ 45 years were selected as the study subjects. Sleep duration was measured by the sum of night and day sleep duration, and depressive symptoms were detected by the Center for Depression Rating Scale (CES-10). Restricted cubic spline model (RCS) and multivariate logistic regression analysis were used to explore the association between them. Results Among the 17293 middle-aged and elderly people, 27.0%, 53.5% and 19.5% had sleep duration < 6 h, 6-8.9 h and ≥ 9 h, respectively. The detection rate of depressive symptoms was 40.2%. RCS analysis showed that there was a U-shaped association between depressive symptoms and sleep duration (χ2 = 512.59, P < 0.001). The results of multivariate logistic regression analysis showed that compared with 7-7.9 h, sleep time < 6 h (OR = 1.309, 95%CI: 1.169–1.466) and 6-6.9 h (OR = 2.393, 95%CI: 2.156–2.656) were associated with high risk of depressive symptoms in middle-aged and elderly people; Sleep duration < 6 h (OR = 1.323, 95%CI: 1.132–1.545) and 6-6.9 h (OR = 2.677, 95%CI: 2.312-3.100) were associated with high risk of depressive symptoms in women; Sleep duration < 6 h (OR = 1.493, 95%CI: 1.291–1.728), 6-6.9 h (OR = 3.454, 95%CI: 3.027–3.940), ≥ 9 h (OR = 1.287, 95%CI: 1.111–1.491) were associated with high risk of depressive symptoms in males; Sleep duration < 6 h (OR = 1.608, 95%CI: 1.295–1.997), 6-6.9 h (OR = 3.584, 95%CI: 2.930–4.385), ≥ 9 h (OR = 1.358, 95%CI: 1.053–1.735) were associated with depressive symptoms in urban middle-aged and elderly men Occurrence of high risk correlation; The sleep duration < 6 h (OR = 1.368, 95%CI: 1.209–1.547) and 6-6.9 h (OR = 3.073, 95%CI: 2.747–3.439) in rural middle-aged and elderly were associated with high risk of depressive symptoms, and the differences were statistically significant (P < 0.05). Conclusion There is a U-shaped association between sleep duration and the risk of depressive symptoms in middle-aged and elderly people. Insufficient sleep-in women and insufficient or too long sleep-in men may increase the risk of depressive symptoms.
Computational analysis revealed Triamcinolone acetonide produced by Bacillus velezensis YEBBR6 as having antagonistic activity against Fusarium oxysporum f. sp. cubense
Authors: U Krishna Nayana R , S Nakkeeran , N Saranya , R Saravanan , K Mahendra , Ashraf Suhail 
Published: October 2022

Abstract

Fusarium oxysporumf. sp.cubenseis one of the most serious and threatening pathogens of banana causing Panama wilt worldwide. Bacterial endophytes were reported to have antifungal action through various mechanisms, which include the production of secondary metabolites during their interaction with pathogen. One such endophyte,Bacillus velezensisYEBBR6 antagonistic toFusarium oxysporumf. sp.cubenseproduced antimicrobial biomolecules against the pathogen during confrontation assay. Those molecules were screened for their antifungal property by anin-silicoapproach. Modelling of the fungal targets and docking them with those biomolecules was done to refine the potential antifungal compounds among the various biomolecules they generated during their di-trophic interaction with the pathogen. Protein targets were selected based on literature mining and those targets were modelled and validated for docking with the biomolecules through the AutoDock Vina module of the PyRx 0.8 server. Among the compounds screened, Triamcinolone acetonide was possessing the maximum binding affinity with chosen pathogen targets. It had the maximum binding affinity of 11.2 kcal/mol with XRN2 (5´ → 3´ Exoribonuclease 2) an enzyme involved in degrading m-RNA -. Kinetics of the protein-ligand complex formation for the further validation of docking results was done through Molecular Dynamic Simulation studies. Besides, the antifungal nature of the biomolecule was also confirmed againstFocby screening in wet lab through poisoned plate technique.
Fiber-specific micro- and macroscopic white matter alterations in progressive supranuclear palsy and corticobasal syndrome
Authors: Kamagata Koji , Uchida Wataru , Andica Christina , Takabayashi Kaito , Saito Yuya , Owaki Mana , Fujita Shohei , Hgiwara Akifumi , Wada Akihiko , Akashi Toshiaki , Sano Katsuhiro , Hori Masaaki , Aoki Shigeki 
Published: October 2022

Abstract
Progressive supranuclear palsy (PSP) and corticobasal degeneration, which frequently present as a corticobasal syndrome (CBS), are characterized by progressive white matter (WM) alterations associated with the prion-like spreading of four-repeat tau. Considering the interplay of tau pathologies with clinical symptoms, capturing the disease-specific patterns of WM alterations might provide valuable clinical information; however, the mechanisms of loss of WM integrity and its involvement in the clinical deficits in tauopathies remain unknown, likely due to the difficulties in estimating complex WM structure. Here, a novel fibre-specific fiber density and fiber cross-section, and their combined measure estimated using fixel-based analysis (FBA), were cross-sectionally and longitudinally assessed in PSP (n = 20) and CBS (n = 17), and healthy controls (n = 20). Cross-sectional and longitudinal FBA indicated disease-specific progression patterns of fiber density loss and subsequent bundle atrophy consistent with the tau propagation patterns suggested in previous histopathological findings. Furthermore, longitudinal changes in fixel-wise metrics in WM tracts which control motor and cognitive functions exhibited strong correlations with changes in clinical dysfunction in both diseases. Our findings suggest that the FBA can be useful in determining the mechanisms of clinical deficits related to sequential WM alterations in PSP and CBS.
WITHDRAWN: Hydrothermal synthesis of rGO loaded CuTiO2 nanocomposite with enhanced visible light photo-catlytic activity for the removal of Rose Bengal dye
Authors: Manikandan Venkatachalam , Krishnamoorthy Umapathi 
Published: October 2022

Abstract
Technological development and Environmental Sustainability are mutually exclusive terms before the Nanotechnology era. With the advent of a diverse variety of nano-materials and composites, an eco-friendly technological development is made possible. One such application is the use of nano-composites in removing pollutants from industrial effluents. Rose Bengal (RB) is an organic dye that belongs to Xanthenes. RB is used extensively in textile, for printing and dying. It also finds an application as insecticide. A particular stain of RB is used in ophthalmology. Also about 20% of the dyes are lost in dyeing, and 19% of the dye is discharged to the environment which in turn pollutes it. Hence it becomes important to treat the effluents before they are discharged or dumped in the environment. Knowing the importance of removing harmful particles from the effluent, present research work synthesizes rGO/CuTiO2 nanocomposite in such a way to improve the photocatalytic dye degradation properties. Standard Hummers method is used for the preparation of Graphene Oxide and hydro-thermal method is adapted for the synthesis of rGO/CuTiO2 nanocomposite. The nano composites so prepared were characterized by UV, FT-IR, XRD, SEM with EDAX and TEM analysis. The structural analysis of monoclinic CuTiO2 composites shows that as the grain size and calcination temperature affects the photocatalytic degradation efficiency. The Degradation efficiency of various nanocomposites say GO, CuTiO2 and rGO/CuTiO2 were evaluated against Rose Bengal dye and it is found that the photocatalytic degradation efficiency is optimum for a RB concentration of 2.28 × 10–5 M, pH of RB = 9.0, and a nanocomposite used is = 0.20 g. It is found that rGO/CuTiO2 nanocomposites calcination temperature at 450oC exhibit superior photocatalystic behavior against Rose Bengal dye (k = 0.0228min-1) under visible light irradiation.
The efficacy and safety of remdesivir and its combination with other drug for the treatment of COVID-19: a systematic review and meta-analysis
Authors: Chen Chuizhe , Fang Junde , Chen Shu , Rajaofera Mamy Jayne Nelly , Li Xuemiao , Wang Bo , Xia Qianfeng 
Published: October 2022

Abstract
Background

Remdesivir was considered to be a specific drug for Corona Virus Disease 2019. This systematic review aims to evaluate remdesivir monotherapy and combination therapy related clinical efficacy and risk.

Research design and methods

PubMed, Embase, SCIE, Cochrane Library, and American Clinical trial Center were searched up to 1 April 2022. We included randomized controlled trials (RCTs) comparing Remdesivir monotherapy with control drugs, or comparing different combination therapy.

Results

11 RCTs and 32 observational studies were included in analysis. In the main outcome, remdesivir use reduced mortality in patients with severe COVID-19 and improve recovery in patients. In other clinical outcomes, remdesivir use was associated with improved clinical status. In safety outcomes, remdesivir use did not cause liver or kidney damage. Compared with remdesivir alone, remdesivir combined with other drugs-steroids, favipiravir, and convalescent plasma- had no effect on mortality. In addition, remdesivir combined with tocilizumab may increase mortality.

Conclusion

Results of the systematic review showed that remdesivir was positive in COVID-19, especially patients with severe COVID-19. The more effective treatment of COVID-19 with other drugs combined with remdesivir is urgent and challenging research.

Trial registration number

PROSPERO registration number: CRD42022322859.
Effects of Betula platyphylla invasion in north China on soil aggregate stability, soil organic carbon and active carbon composition of larch plantation
Authors: Ma Ying , Wu Huifeng , Hu Baoan , Cheng Xiaoqin , Kang Fengfeng , Han Hairong 
Published: October 2022

Abstract
Aims
In order to better understand the changes in the potential carbon sequestration capacity of forest soil after the invasion of broad-leaved trees into pure larch plantations, the effects of broadleaf tree invasion on soil aggregate stability and carbon sequestration by soil organic carbon and active carbon components were studied.
Methods
In northern China, the pure Larix principis-rupprechtii plantations and the Larix principis-rupprechtii plantations invaded by Betula platyphylla at various degrees with the same site conditions were selected (Betula platyphylla had a mixed degree of 0.2 and 0.4, respectively). ANOVA, correlation analysis, principal component analysis and structural equation were conducted to interpret the relations between Betula platyphylla invasion and soil properties.
Results
The distribution of soil macroaggregates (> 0.25 mm) increased with the increase in the mixed degree of Betula platyphylla. The mixture of Betula platyphylla could effectively increase the organic carbon and active carbon components of the original soil and soil aggregates of different diameter classes. The forest growth in this study area was mainly limited by nitrogen. The invasion of Betula platyphylla had an indirect impact on soil carbon sequestration by affecting the soil physical and chemical properties and the aggregate stability.
Conclusions
The invasion of Betula platyphylla had significant positive effects on soil aggregate stability, erosion resistance and soil nutrient status in Larix principis-rupprechtii plantation. The coniferous and broad-leaved mixture was a good strategy to increase the soil quality and soil organic carbon sequestration of the Larix principis-rupprechtii plantation in this area.
Short-term hypothyroidism transiently impaired endothelial function in differentiated thyroid cancer patients
Authors: Hou Li-ying , Li Xiao , Zhang Guo-qiang , Xi Chuang , Shen Chen-tian , Song Hong-jun , Bai Wen-kun , Qiu Zhong-ling , Luo Quan yong 
Published: October 2022

Abstract
Purpose:

Endothelial dysfunction, which was associated with chronic hypothyroidism, was an early event in atherosclerosis. Whether short-term hypothyroidism following thyroxine withdrawal during radioiodine (RAI) therapy was associated with endothelial dysfunction in patients with differentiated thyroid cancer (DTC) was unclear. Aim of the study is to assess whether short-term hypothyroidism could impair endothelial function in the whole process of RAI therapy.

Methods:

We recruited fifty-one patients who underwent surgery and would accept RAI therapy for DTC. We analyzed thyroid function, endothelial function and serum lipids levels in patients at three time points: the day before thyroxine withdrawal (P1), the day before RAI administration (P2) and 4–6 weeks after RAI therapy (P3). A high-resolution ultrasound named flow-mediated dilation (FMD) was used to measure endothelial function of the patients.

Results:

We defined the FMD(%) value decreasing by more than 1% as impaired value. We analyzed the changes of FMD, thyroid hormone and lipids at three time points. FMD (%) was impaired at P2 compared to P1 and was recovered at P3 after restoring LT4 therapy (P1 vs P2 vs P3, 8.05±1.55 vs 7.26±1.50 vs 7.79 ± 1.38, P = 0.438). Among all parameters, the change of LDL cholesterol (ΔLDL) was the only factor correlated negatively with the change of FMD (ΔFMD) throughout the RAI therapy process (P1 − 2, r=-0.326, P = 0.020; P2 − 3, r=-0.306, P = 0.029).

Conclusion:

Endothelial function was transiently impaired in DTC patients at short-term hypothyroidism state during the RAI therapy, and immediately returned to the same state before RAI therapy after restoring LT4 therapy.