bluuebunny/crossref_metadata_2025_split huggingface dataset:
SARS-CoV-2 antibody persistence after five and twelve months: A cohort study from South-Eastern Norway
Authors: Sarjomaa Marjut , Diep Lien My , Zhang Chi , Tveten Yngvar , Reiso Harald , Thilesen Carina , Nordbø Svein Arne , Berg Kristine Karlsrud , Aaberge Ingeborg , Pearce Neil , Kersten Hege , Vandenbroucke Jan Paul , Eikeland Randi , Fell Anne Kristin Møller 
Published: August 2022

ObjectivesTo assess total antibody levels against Severe Acute Respiratory Syndrome CoronaVirus 2 (SARS CoV-2) spike protein up to 12 months after Coronavirus Disease (COVID-19) infection in non-vaccinated individuals and the possible predictors of antibody persistence.MethodsThis is the first part of a prospective multi-centre cohort study.ParticipantsThe study included SARS-CoV-2 real-time polymerase chain reaction (RT-PCR) positive and negative participants in South-Eastern Norway from February to December 2020. Possible predictors of SARS-CoV-2 total antibody persistence was assessed. The SARS-CoV-2 total antibody levels against spike protein were measured three to five months after PCR in 391 PCR-positive and 703 PCR-negative participants; 212 PCR-positive participants were included in follow-up measurements at 10 to 12 months. The participants completed a questionnaire including information about symptoms, comorbidities, allergies, body mass index (BMI), and hospitalisation.Primary outcomeThe SARS-CoV-2 total antibody levels against spike protein three to five and 10 to 12 months after PCR positive tests.ResultsSARS-CoV-2 total antibodies against spike protein were present in 366 (94%) non-vaccinated PCR-positive participants after three to five months, compared with nine (1%) PCR-negative participants. After 10 to 12 months, antibodies were present in 204 (96%) non-vaccinated PCR-positive participants. Of the PCR-positive participants, 369 (94%) were not hospitalised. The mean age of the PCR-positive participants was 48 years (SD 15, range 20–85) and 50% of them were male. BMI ≥ 25 kg/m2was positively associated with decreased antibody levels (OR 2.34, 95% CI 1.06 to 5.42). Participants with higher age and self-reported initial fever with chills or sweating were less likely to have decreased antibody levels (age: OR 0.97, 95% CI 0.94 to 0.99; fever: OR 0.33, 95% CI 0.13 to 0.75).ConclusionOur results indicate that the level of SARS-CoV-2 total antibodies against spike protein persists for the vast majority of non-vaccinated PCR-positive persons at least 10 to 12 months after mild COVID-19.
Fetal size classified using gestational days rather than gestational weeks improves correlation with stillbirth risk: A statewide population study
Authors: Pritchard Natasha L. , Tong Stephen , Walker Susan P. , Lindquist Anthea C. 
Published: August 2022

Objective
Many growth charts provide single centile cutoffs for each week of gestation, yet fetuses gain weight throughout the week. We aimed to assess whether using a single centile per week distorts the proportion of infants classified as small and their risk of stillbirth across the week.

Design
Retrospective cohort study.

Setting
Victoria, Australia.

Population
Singleton, non-anomalous infants born from 2005–2015 (529,261).

Methods
We applied growth charts to identify small-for-gestational-age (SGA) fetuses on week-based charts (single centile per gestational week) and day-based charts (centile per gestational day).

Main outcome measures
Proportions <10th centile by each chart, and stillbirth risk amongst SGA infants.

Results
Using week-based charts, 12.1% of infants born on the first day of a gestational week were SGA, but only 7.8% on the final day; ie. an infant born at the end of the week was 44% less likely to be classed as SGA (p<0.0001). The relative risk of stillbirth amongst SGA infants born on the final day of the week compared with the first was 1.47 (95%CI 1.09–2.00, p = 0.01). Using day charts, SGA proportions were similar and stillbirth risk equal between the beginning and end of the week (9.5% vs 9.9%).

Conclusions
Growth standards using a single cutoff for a gestational week overestimate the proportion of infants that are small at the beginning of the week and underestimate the proportion at the end. This distorts the risk of stillbirth amongst SGA infants based on when in the week an infant is born. Day-based charts should be used.
All trans-retinoic acid modulates hyperoxia-induced suppression of NF-kB-dependent Wnt signaling in alveolar A549 epithelial cells
Authors: Tsotakos Nikolaos , Ahmed Imtiaz , Umstead Todd M. , Imamura Yuka , Yau Eric , Silveyra Patricia , Chroneos Zissis C. 
Published: August 2022

IntroductionDespite recent advances in perinatal medicine, bronchopulmonary dysplasia (BPD) remains the most common complication of preterm birth. Inflammation, the main cause for BPD, results in arrested alveolarization. All trans-retinoic acid (ATRA), the active metabolite of Vitamin A, facilitates recovery from hyperoxia induced cell damage. The mechanisms involved in this response, and the genes activated, however, are poorly understood. In this study, we investigated the mechanisms of action of ATRA in human lung epithelial cells exposed to hyperoxia. We hypothesized that ATRA reduces hyperoxia-induced inflammatory responses in A549 alveolar epithelial cells.MethodsA549 cells were exposed to hyperoxia with or without treatment with ATRA, followed by RNA-seq analysis.ResultsTranscriptomic analysis of A549 cells revealed ~2,000 differentially expressed genes with a higher than 2-fold change. Treatment of cells with ATRA alleviated some of the hyperoxia-induced changes, including Wnt signaling, cell adhesion and cytochrome P450 genes, partially through NF-κB signaling.Discussion/ConclusionOur findings support the idea that ATRA supplementation may decrease hyperoxia-induced disruption of the neonatal respiratory epithelium and alleviate development of BPD.
Políticas educativas y equidad: Introducción al monográfico
Authors: Rodríguez-Martínez Carmen , Martín-Alonso Diego , Marrero-Acosta Javier 
Published: August 2022

En este texto se presenta el monográfico Políticas Educativas y Equidad, cuyo interés recae en profundizar en diferentes contextos -políticos, de gestión administrativa, educativos y formativos, para identificar, describir y comprender políticas y prácticas relacionadas con la promoción de la equidad entendida como el derecho fundamental a la educación, combatiendo la vulnerabilidad, la dependencia y la dominación, y con la reducción de la desigualdad y discriminación. Tras una breve introducción del marco teórico desde el que se plantea este monográfico, se presentan los artículos que lo componen. Los temas que se abordarán, desde los marcos de la investigación cualitativa, giran en torno a: los diferentes niveles del proceso de formulación de políticas educativas; las políticas de privatización y las relaciones entre lo público y lo privado; los procesos de digitalización de las escuelas; los procesos de globalización y sus consecuencias para los agentes y la democracia; las políticas de diversificación; la formación del profesorado y su impacto en la equidad; así como programas educativos que buscan la construcción de prácticas que se orientan a la inclusión y la equidad.
A Working Paper on the Regulatory Environment for Autonomous Vehicles
Authors: Chieppo Charles , Giglio Joseph M. 
Published: August 2022

Whether it be 5, 10 or 20 years from now, fully self-driving care, also known as autonomous vehicles, are coming in the not-too-distant future. Yet despite the fact that driverless robo-taxis are already operating in some jurisdictions, there are still no federal regulations to guide their deployment. Autonomous vehicles will have – in in some places are already having – dramatic impacts on consumer mobility habits, the transportation and technology industries, and the economy as a whole. Yet despite the major disruption they represent, there are no national regulations guiding autonomous vehicle development. Instead, it is a state-by-state patchwork of regulations that guide the industry. The lack of standardization a uniform national regulatory framework would delay the development of autonomous vehicles and make it impossible for developers to achieve the the economies of scale standardization would bring – economies of scale that are critical for this new technology to be economically viable.
Individual corpus data predict variation in judgments: testing the usage-based nature of mental representations in a language transfer setting
Authors: Barking Marie , Backus Ad , Mos Maria 
Published: August 2022

Abstract
This study puts the usage-based assumption that our linguistic knowledge is based on usage to the test. To do so, we explore individual variation in speakers’ language use as established based on corpus data – both in terms of frequency of use (as a proxy for entrenchment) and productivity of use (as a proxy for schematization) – and link this variation to the same participants’ responses in an experimental judgment task. The empirical focus is on transfer by native German speakers living in the Netherlands, who oftentimes experience transfer from their second language Dutch to their native language German regarding the placement of prepositional phrases. The analyses show a large amount of variation in both the corpus and experimental data with a strong link across data types: individual speakers’ usage – but not the usage by other speakers – is a significant predictor for the speakers’ judgments. These results strongly suggest that, in line with a usage-based approach, variation between speakers in experimental tasks is linked to their variation in usage. At the same time, such usage-based predictions do not explain all of the variation, suggesting that other individual factors are also at play in such experimental tasks.
LncRNA-p21 suppresses cell proliferation and induces apoptosis in gastric cancer by sponging miR-514b-3p and up-regulating ARHGEF9 expression
Authors: Ma Xiaobin , Yan Wenyu , Xu Peng , Ma Li , Zan Ying , Huang Lanxuan , Wang Guanying , Liu Lili , Hui Wentao 
Published: August 2022

Abstract
The long non-coding RNA p21 (lncRNA-p21) was a tumor suppressor gene in most cancer types including gastric cancer (GC). We aimed to identify a specific lncRNA-p21-involved pathway in regulating the proliferation and apoptosis of GC cells. A lower lncRNA-p21 expression in tumors was associated with advanced disease stage and predicted worse survival of GC patients. LncRNA-p21 overexpression in GC cell line somatic gastric cancer (SGC)-7901 and human gastric cancer (HGC)-27 suppressed cell proliferation and enhanced apoptosis, while lncRNA-p21 knockdown caused the opposite effects. Through bioinformatics analysis and luciferase-based reporter assays, we identified miR-514b-3p as a sponge target of lncRNA-p21. Cdc42 guanine nucleotide exchange factor 9 (ARHGEF9), functioned as a tumor suppress factor in GC, was found as the downstream target of miR-514-3p, and their expressions were negatively correlated in GC tumor tissues. In addition, like lncRNA-p21 overexpression alone, miR-514-3p inactivation alone also led to decreased proliferation and increased apoptosis in SGC-7901 and HGC-27 cells, which were markedly attenuated by additional ARHGEF9 knockdown. Xenograft SGC-7901 cells with more lncRNA-p21 or ARHGEF9 expressions or with less miR-514-3p expression exhibited obviously slower in vivo growth than the control SGC-7901 cells in nude mice. Our study reveals a novel lncRNA-p21/miR-514b-3p/ARHGEF9 pathway that can be targeted for GC therapy.
Aboriginal linguistic exchange in an Australian city
Authors: Mansfield John 
Published: August 2022

AbstractTropical northern Australia is a region of high linguistic diversity, with dozens of language varieties each spoken by a small number of people. Traditionally, this level of diversity has been supported by egalitarian linguistic ecologies, where Aboriginal people use multiple languages alongside one another in each local region. In this study, I explore new types of multilingual practices that are emerging in Darwin, the only major city in the area. Aboriginal people from the homelands often visit Darwin, and some become permanent residents, which provides the context for new types of multilingual encounters. Kriol and English are also used as a ‘fall-back’ languages to mitigate gaps in understanding, which allows multilingual interaction to occur between people who have only partial knowledge of eachothers’ languages. I characterise these practices as ‘linguistic exchange’, used by speakers to establish their links to kin and country, while also showing respect for their interlocutor’s social connections. Linguistic exchange also supports the distinctive Aboriginal mode of demand-driven resource sharing. Aboriginal language use in Darwin suggests that urban mobility is not necessarily detrimental to the future vitality of the region’s rich linguistic heritage.
LncRNA LINC01857 reduces metastasis and angiogenesis in breast cancer cells via regulating miR-2052/CENPQ axis
Authors: Qian Weiwei , Yang Linlin , Ni Yi , Yin Fei , Qin Lili , Yang Yang 
Published: August 2022

Abstract
Long non-coding RNAs have been confirmed closely related to the metastasis and angiogenesis of breast cancer (BC). LINC01857 can promote the growth and metastasis of BC cells. The present work focused on exploring the role of LINC01857 in BC metastasis and angiogenesis and investigating the possible mechanisms. The results showed that LINC01857 and CENPQ were highly expressed in BC tissues and cells, while miR-2052 was contrarily expressed. In vitro study showed that low expression of linc01857 could inhibit the migration ability and vascularization of BC cells, and mir-2052 inhibitor partially restored the effect of si-LINC01857 on the migration ability and vascularization of BC cells. Likewise, inhibition of CENPQ can partially rescue the effects of miR-2052 inhibitor on the migration ability and vascularization of BC cells. In vivo studies showed that down-regulation of LINC01857 notably suppressed tumor growth and angiogenesis in nude mice. The miR-2052 inhibitor partially restored the effects of si-LINC01857. CENPQ suppression partially rescued the effects of the miR-2052 inhibitor. To conclude, LINC01857/miR-2052/CENPQ is the potential novel target for BC treatment.
Stories worth sharing: high school students from diverse backgrounds tell their stories
Authors: Johnston Vickie , Martelli Cynthia Dawn 
Published: August 2022

Abstract
This qualitative case study examined the effect of writing sessions, conducted at a university literacy festival, on the construction of college admission essays. Sessions were conducted by authors of multicultural young adult literature and university writing center staff and students. Each session focused on helping 132 high school students from Title 1 schools use their voice to share their social and cultural experiences. Essays and reflective responses from participants, authors, university writing center staff, and university freshman mentors were analyzed. Analysis of essays revealed four themes: overcoming hardship, involvement in academic and extracurricular programs, cultural and ethnic identity, and positive role models; analysis of reflections revealed three themes: an increase in confidence in writing, a new understanding that participants’ stories could affect others, and barriers to attending college. Findings indicated that author and university writing sessions were effective in promoting writing strategies for under-supported high school students constructing college essays.
The Background to “Fight the Good Fight” in 1 Timothy 1:18, 6:12, and 2 Timothy 4:7
Authors: Beale G. K. 
Published: August 2022

Abstract
The combined wording in 1 Tim 1:18 of στρατεύω + στρατεία can be rendered in English “fight the fight,” “battle the battle,” or more generally “perform military service” or “serve in a military campaign.” The combination surprizingly occurs often throughout Greco-Roman literature to express a patriotic warfare idiom for good character revealed by persevering through warfare or military campaigns. This idiom is applied to Timothy to demonstrate his good Christian character and reputation over against the false teachers’ bad character. The idiom also occurs often in a legal context to affirm a person’s character and good reputation, which qualifies a person to be an officer of the court or endorses a person’s character before the court in a legal dispute, showing him to be worthy of an innocent verdict. In 1 Timothy this idiom is used in a legal context (accompanied repeatedly by the μάρτυς word group, as in the Hellenistic occurrences of the idiom) that demonstrates and acquits Timothy’s character and reputation before the false teachers. The redundant word combination of ἀγωνίζομαι + ἀγών (“struggle the struggle”) in 1 Tim 6:12 and 2 Tim 4:7 is recognized by commentators as a development of the phrase in 1 Tim 1:18. In the Greek world, this also is a well-worn idiom used in the same way as the στρατεύω + στρατεία expression, most likely highlighting the difficulty of the fight. This is why the expression ἀγωνίζομαι + ἀγών is synonymous with the expression in 1 Tim 1:18, even with the added adjective “good.” This is also why some English translations even translate the redundant expressions in 1 Tim 1:18, 1 Tim 6:12, and 2 Tim 4:7 as “fight the good fight,” clearly seeing στρατεύω + στρατεία and ἀγωνίζομαι + ἀγών as synonymous. This lexical study of Greco-Roman backgrounds endorses the conclusion that the two expressions are idioms and are synonymous.
What Are These Sons Doing? Filial Agency in New Testament and Early Rabbinic Writings
Authors: Oegema Albertina 
Published: August 2022

Abstract
Scholarship on children and childhood in the New Testament and the Hebrew Bible increasingly uses the term “agency” for children’s actions. However, the use of this term remains undertheorized. This article offers a theoretically informed usage of the concept “agency” so as to analyze the dynamics in children’s actions. With a comparative study of Synoptic and early rabbinic parables, it is examined how a son’s agency interrelates with his father’s exercise of authority. It is also shown how the behaviour of these sons is implicitly or explicitly assessed from the adult male perspective of the head of the household. Finally, since the agency of sons frequently represents the human free will in relation to God, the article explains how the Synoptic and early rabbinic parables socialize their audiences in their correct attitude toward God.
The Criterion Validity and Between-Day Reliability of the Perch for Measuring Barbell Velocity During Commonly Used Resistance Training Exercises
Authors: Weakley Jonathon , Munteanu Gabriella , Cowley Nicholas , Johnston Rich , Morrison Matthew , Gardiner Carissa , Pérez-Castilla Alejandro , García-Ramos Amador 
Published: August 2022

Abstract
Weakley, J, Munteanu, G, Cowley, N, Johnston, R, Morrison, M, Gardiner, C, Pérez-Castilla, A, and García-Ramos, A. The criterion validity and between-day reliability of the Perch for measuring barbell velocity during commonly used resistance training exercises. J Strength Cond Res XX(X): 000–000, 2022—This study aimed to assess the criterion validity and between-day reliability (accounting for technological and biological variability) of mean and peak concentric velocity from the Perch measurement system. On 2 testing occasions, 16 subjects completed repetitions at 20, 40, 60, 80, 90, and 100% of 1-repetition maximum in the free-weight barbell back squat and bench press. To assess criterion validity, values from the Perch and a 3-dimensional motion capture system (criterion) were compared. Technological variability was assessed by determining whether the differences between the Perch and criterion for each load were comparable for both testing sessions, whereas between-day reliability with both technological and biological variability was calculated from Perch values across days. Generalized estimating equations were used to calculate R

2
and root mean square error, whereas Bland-Altman plots assessed magnitude of difference between measures. To support monitoring of athletes over time, standard error of measurement and minimum detectable changes (MDC) were calculated. There was excellent agreement between the Perch and criterion device, with mean velocity in both exercises demonstrating a mean bias ranging from −0.01 to 0.01 m·s−1. For peak velocity, Perch underestimated velocity compared with the criterion ranging from −0.08 to −0.12 m·s−1 for the back squat and −0.01 to −0.02 m·s−1 for the bench press. Technological variability between-days were all less than the MDC. These findings demonstrate that the Perch provides valid and reliable mean and peak concentric velocity outputs across a range of velocities. Therefore, practitioners can confidently implement this device for the monitoring and prescription of resistance training.
Biografien und Netzwerke im Kaffeehandel zwischen Deutschland und Zentralamerika 1920–1959
Authors: Berth Christiane 
Published: August 2022

Kaffee ist nicht nur ein beliebtes Getränk, sondern vernetzte auch unterschiedliche Welten: Der Kaffeehandel band Hamburg und Bremen in transnationale Netzwerke ein, die sich zwischen Europa und Lateinamerika erstreckten.
Zentralamerika war für den globalen Kaffeehandel wichtig, weil die Region als erste die „nasse“ Form der Aufbereitung einführte. Die hohe Qualität dieser „gewaschenen“ Kaffees machte sie auf dem Weltmarkt begehrt. Deutsche Einwanderer prägten die Handelsverbindungen zwischen den zentralamerikanischen Kaffee-Anbauregionen und den norddeutschen Hafenstädten: Sie gründeten Exportfirmen, erwarben Kaffeeplantagen und beteiligten sich an der Vorfinanzierung der Ernten.
Christiane Berth analysiert Biografien und Netzwerke deutscher Kaffee-Akteure in Guatemala, Costa Rica und Chiapas. Dabei zeigt sie, wie deren Handelsnetzwerke durch wirtschaftliche Krisen und neue außenpolitische Konstellationen brüchig wurden, im Nationalsozialismus unter Druck gerieten und während des Zweiten Weltkrieges zerbrachen. Trotzdem blieben auch in der Nachkriegszeit Handelsbeziehungen zwischen Nationalstaaten, Netzwerke in der Kaffeebranche und Biografien der Kaffee-Akteure eng miteinander verknüpft.
Effect of Aronia melanocarpa fruit juice on glucose tolerance, lipid metabolism, and obesity in a rat model of metabolic syndrome
Authors: Reyzov M. , Eftimov M. , Gancheva S. , Todorova M. , Zhelyazkova-Savova M. , Tzaneva M. , Valcheva-Kuzmanova S. 
Published: August 2022

Abstract
Metabolic syndrome (MS) is a serious health condition. The purpose of this study was to investigate the effects of polyphenol-rich Aronia melanocarpa fruit juice (AMFJ) on glucose tolerance, triglyceride levels, and adipose tissue in rats with MS induced by high-fat high-fructose (HFHF) diet. Fifty rats were allocated in 5 groups: control, MS, MS+AMFJ2.5, MS+AMFJ5, and MS+AMFJ10. In the course of 10 weeks, the control group was on a regular rat diet while the other groups received HFHF diet. During the experiment, control and MS groups were treated daily orally with distilled water (10.0 mL kg−1) and the other three groups – with AMFJ at doses of 2.5, 5.0, and 10.0 mL kg−1, respectively. In MS rats, glucose intolerance, hypertriglyceridemia, visceral obesity, and increased adipocyte size were observed. In AMFJ-treated groups, the serum glucose and triglycerides, as well as visceral fat and adipocyte size decreased significantly and did not differ from those of the control group. AMFJ at doses 2.5 and 5.0 mL kg−1 showed an anti-apoptotic activity in adipocytes, while at the dose of 10 mL kg−1 a pro-apoptotic effect was detected. In conclusion, AMFJ could antagonise most of the negative consequences of HFHF diet on carbohydrate and lipid metabolism in a rat MS model.