bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving static balance ability with trainings supported by somatosensory-based feedback system
Authors: Wang Wei , Wang Wenjing , Shadiev Rustam 
Published: December 2022

AbstractTo support trainings for static balance ability improvement, in this study, we developed a somatosensory-based feedback system (SFS) using Kinect technology. Three training tasks such as knees crouch, rotating upper body and rotating upper body with a ball in hands were designed according to the static balance ability training method. Forty-four participants volunteered to participate in the study. The participants completed these tasks by performing three movements during a six-week period. Feedback, either positive or negative, on the participants’ static balance performance was provided by the SFS to adjust their posture and static balance. We tested the effectiveness of the SFS on improving the static balance ability in an experiment. The participants were randomly assigned to a control group (n = 22) and an experimental group (n = 22). The participants in the experimental group completed the training tasks with the support of the SFS, whereas the participants in the control group completed the training tasks without any feedback. A static balance ability pretest was administered before the training and a static balance ability posttest after the training. Differences between two groups on tests’ results were compared. In addition, the participants in the experimental group completed intermediate tests (the same test as the pre- and post-test) during the training. Three main findings were obtained. First, there was no difference between the two groups in the static balance ability pretest; however, the experimental group outperformed the control group on the static balance ability posttest. Second, the participants’ scores for the single barefoot standing using the dominant leg with eyes opened (SFOE) and single barefoot standing using the dominant leg with eyes closed (SFCE) testing tasks were higher than those in the double barefoot standing with eyes opened (DFOE) and double barefoot standing with eyes closed (DFCE) testing tasks. Third, there were improvements in swing path, swing speed, swing amplitude, and area research variables. According to interviews with the participants, the SFS was useful, as it provided feedback to the static balance performance and they used it to adjust their postures and balance. Based on the results, we suggest applying the SFS to trainings for static balance ability as it can improve the static balance ability.
Dissecting the essential role of N-glycosylation in catalytic performance of xanthan lyase
Authors: Zhao Jingjing , Wang Qian , Ni Xin , Shen Shaonian , Nan Chenchen , Li Xianzhen , Chen Xiaoyi , Yang Fan 
Published: December 2022

AbstractModified xanthan produced by xanthan lyase has broad application prospects in the food industry. However, the catalytic performance of xanthan lyase still needs to be improved through rational design. To address this problem, in this work, the glycosylation and its influences on the catalytic performance of a xanthan lyase (EcXly), which was heterologously expressed in Escherichia coli, were reported. Liquid chromatography coupled to tandem mass spectrometry analysis revealed that the N599 site of EcXly was modified by a single N-glycan chain. Based on sequence alignment and three-dimensional structure prediction, it could be deduced that the N599 site was located in the catalytic domain of EcXly and in close proximity to the catalytic residues. After site-directed mutagenesis of N599 with alanine, aspartic acid and glycine, respectively, the EcXly and its mutants were characterized and compared. The results demonstrated that elimination of the N-glycosylation had diminished the specific activity, pH stability, and substrate affinity of EcXly. Fluorescence spectra further revealed that the glycosylation could significantly affect the overall tertiary structure of EcXly. Therefore, in prokaryotic hosts, the N-glycosylation could influence the catalytic performance of the enzyme by changing its structure. To the best of our knowledge, this is the first report about the post-translational modification of xanthan lyase in prokaryotes. Overall, our work enriched research on the role of glycan chains in the functional performance of proteins expressed in prokaryotes and should be valuable for the rational design of xanthan lyase to produce modified xanthan for industrial application.
Graphical Abstract
A Skill Acquisition Perspective on the Impact of Exergaming Technology on Foundational Movement Skill Development in Children 3–12 Years: A Systematic Review and Meta-analysis
Authors: Oppici Luca , Stell Frederike Marie , Utesch Till , Woods Carl T. , Foweather Lawrence , Rudd James R. 
Published: December 2022

Abstract
Background
Sedentary, digital screen time in children represents a major concern due to its detrimental effect on children’s development. Nowadays, however, advances in technology allow children to actively interact with a digital screen using their whole body (e.g., exergaming), providing potential for movement learning. Exergaming technology may prove valuable in supporting children’s development of foundational movement skills (FMS).

Objective
To examine the impact of exergaming technology on the development of FMS in children 3–12 years through a skill acquisition lens.

Methods
Systematic review and meta-analysis were conducted following the PRISMA guidelines. Web of Science, PubMed, PsycINFO and SPORTDiscus databases were searched between 2007 and 2022. Studies were eligible if they conducted an exergaming intervention to improve FMS in typically developing children aged three to twelve with a control group, using a baseline and post-intervention assessment design. FMS outcomes were pooled with a random effects model.

Results
Nine trials (4 RCTs, 2 cluster RCTs and 3 non-randomized trials) of varying methodological quality (2 had low, 6 had some concerns, and 1 had a high risk of bias) were included, with a total of 783 participants. FMS outcome measures across studies comprised object control skills, locomotor skills, coordination, agility, balance and balance-related skills. The meta-analysis included showed a small positive effect in favor of the exergaming intervention (r = 0.24 [95% confidence interval: 0.11–0.36]).

Conclusion
Our results indicate that screen-based technology that requires an active engagement of the child can promote the development of FMS. Considering that FMS are the foundation of a child’s physical, mental, health and academic development, this finding could lead to a reshaping of the perception of digital screen-based technology and the role this should play in children’s lives. We speculate that the observed benefits most likely depend upon the quality of information–movement coupling specificity and the motor learning strategies built into the exergame and/or the intervention design. We do not believe this is dependent on the type of FMS being performed or the amount of practice. We recommend therefore that future research should examine how practitioners (school teachers, coaches and parents) can facilitate the interaction between a child and exergaming technology.
Cardiovascular events by different target hemoglobin levels in ESA-hyporesponsive hemodialysis patients: a multicenter, open-label, randomized controlled study
Authors: Nitta Kosaku , Kuragano Takahiro , Joki Nobuhiko , Tsuruya Kazuhiko , Honda Hirokazu , Hamano Takayuki , Fujii Hideki , Uemura Yukari , Tsuchiya Ken ,   the PARAMOUNT-HD Study Investigators, Ohashi Yasuo 
Published: December 2022

Abstract
Background
The incidence of cardiovascular (CV) events is high in hemodialysis (HD) patients and is associated with hyporesponsiveness to erythropoiesis-stimulating agents (ESAs). However, there are no recommended target hemoglobin ranges for ESA-hyporesponsive patients.

Methods
We randomly assigned 304 ESA-treated HD patients with ESA hyporesponsiveness to a proactive treatment group (target hemoglobin level 11 g/dL) or maintenance treatment group (target hemoglobin level 9–10 g/dL), both of which received epoetin beta pegol. The primary outcome was time to the first CV event. CV events included cardiac death, heart failure, and acute coronary syndrome requiring hospitalization. The patients were followed for 24 months.

Results
The proactive and maintenance treatment groups had mean baseline hemoglobin levels of 9.34 and 9.32 g/dL, respectively. Mean hemoglobin levels during the observation period were 10.58 and 10.26 g/dL (P < 0.001), and mean durations of hemoglobin level > 10.5 g/dL were 11.5 and 8.6 months (P < 0.001), respectively. Cox proportional hazards analysis demonstrated a significantly lower risk of CV events in the proactive group (hazard ratio [HR], 0.43; 95% confidence interval [CI], 0.19–0.96). This lower risk was driven by lower incidence of hospitalization-required congestive heart failure. A longer duration of hemoglobin level > 10.5 g/dL was associated with a lower risk of CV events (HR, 0.92/month; 95% CI, 0.87–0.98).

Conclusions
Targeting hemoglobin levels of 11 g/dL with epoetin beta pegol reduces CV risk in Japanese HD patients with ESA hyporesponsiveness.
Trial registration: University Hospital Medical Information Network (UMIN) database (UMIN000010138), registered on March 1, 2013.
Histological study on the skin structure in two mudskippers, Periophthalmus waltoni and Boleophthalmus dussumieri in relation to their terrestrial life
Authors: Dorostghoal Mehran , Jazayeri Ashraf , Ashiri Sara 
Published: December 2022

AbstractMicroscopic structure of skin in two amphibious mudskipper fish; Boleophthalmus dussumieri Valenciennes, 1837 (B. dussumeri) and Periophthalmus waltoni Koumans, 1941 (P. waltoni) were investigated in relation to their lifestyle. The general structure of skin is the same among the two species. Epidermis in B. dussumeri was thicker significantly than P. waltoni. The dermal bulges were only well developed in the skin of B. dussumeri. Mucous cells were absent in the epidermis of P. waltoni but present in B. dussumeri. Both B. dussumeri and P. waltoni have well-developed swollen middle cells as a shared epidermal feature. The thickness of the middle cell layer of the epidermis in B. dussumeri was significantly greater than in P. waltoni. Capillaries in the dorsal and ventral parts of the body are more closely distributed to the epidermal surface in P. waltoni than in B. dussumeri. The diffusion distance in the dorsal epidermis of P. waltoni was less than that in the ventral epidermis of B. dussumeri. A comparative examination of the skin of mudskipper species suggests that, due to the more terrestrial lifestyle adopted by P. waltoni, the skin contributes more to respiration.
Effects of industrialization on Tanzania’s economic growth: a case of manufacturing sector
Authors: Lugina Eunice Jonathan , Mwakalobo Adam Beni Swebe , Lwesya Francis 
Published: December 2022

AbstractThis article examines the impact of industrialization on economic growth in Tanzania focusing on the drivers of structural changes in the manufacturing sector. We apply the vector error correction model based on a parsimonious model covering the period from 1970 to 2017. Our results demonstrate the existence of a positive relationship between the manufacturing sector through its value added and economic growth in Tanzania. We have also observed a similar pattern of relationship in other sectors of the economy such as construction, agriculture, and services. Furthermore, the interaction model shows that foreign direct investment inflows and net domestic credit are the drivers of manufacturing growth. However, the real exchange rate coefficient is negative and significant, suggesting that it has had a negative impact on manufacturing output. The results are consistent with postulations of economic models found in economic growth theories. The article also presents some policy implications regarding the need for consistent policy implementation in the manufacturing sector and further improvement of the investment climate.
Identification of modal parameters of long-span bridges under various wind velocities
Authors: Lu Siying , Yan Lei , He Xuhui , Guo Hui 
Published: December 2022

AbstractThe modal parameters identification of bridges under non-stationary environmental excitation has caught the attention of researchers. This paper studies the non-stationarity of wind velocity, and extracts the time-varying mean wind velocity based on a discrete wavelet transform and recursive quantitative analysis. The calculated turbulence intensity and turbulence integral scale under the non-stationary model are smaller than those under the stationary model, especially the turbulence integral scale. The empirical wavelet transform is used to identify the modal parameters of long-span bridges, and the power spectral density spectrum is proposed as a replacement for the Fourier spectrum as the basis of the frequency band selection. The bridge modal parameters are then compared using the covariance-driven stochastic subspace system identification method (SSI-COV) and the Hilbert transform method based on an improved empirical wavelet transform (EWT-HT). Both methods can accurately identify the modal frequency, and the absolute difference between these two methods is equal to 0.003 Hz. The wind velocity results in a change of less than 1% in the modal frequency. The absolute difference between the modal damping ratios identified using SSI-COV and EWT-HT is significant and can reach 0.587%. The modal damping ratios are positively correlated with the mean wind velocities, which aligns with the quasi-steady assumption. In addition, the applicability of SSI-COV and EWT-HT is also evaluated using the standard deviation, coefficient of variation, and range dispersion indicators. The results show that the EWT-HT is more applicable to the identification of the modal parameters of long-span bridges under non-stationary wind velocities.
Evaluation of microplastics sediment sampling techniques—efficiency of common methods and new approaches
Authors: Adomat Yasmin , Kahl Melanie , Musche Fabian , Grischek Thomas 
Published: December 2022

AbstractCommon sediment samplers for microplastics (MP) such as grab samplers or corers are limited to certain grain sizes and known to cause disruption of sediments which results in a loss of fine and low-density particles such as MP. However, this loss has not been quantified yet and its occurrence is commonly tolerated during MP sediment sampling. In the present study we evaluate the recovery of MP of various common sediment samplers used in most recent studies. The samplers were tested on a model plant simulating a riverine environment with MP spiked sediments. Also, we investigated the feasibility of less frequently used freeze coring. The results of this study suggest that a combination of common methods is crucial in order to sufficiently evaluate a sampling site until standardized MP samplers for sediments are available. Freeze coring indicates a promising potential to monitor MP in river sediments in the future but is costly and should be optimized for regular field sampling campaigns.
Graphical Abstract
Evaluation of modified cashew nutshell liquid as natural surfactants for chemical flooding in sandstone oil reservoirs
Authors: Obuebite Amalate Ann , Eke William Iheanyi , Udoh Tinuola 
Published: December 2022

AbstractBio-based oilfield chemicals are gaining attention due to their availability, cost-effectiveness, and non-toxic nature. Surfactants facilitate recovery of residual oil by reducing the interfacial tension between two immiscible fluids. Cashew nutshell liquid (CNSL) extracted from Anacardium occidentale waste shells was modified using triethanolamine and evaluated as a natural alternative to traditional surfactants. Phase behavior analysis, interfacial tension, critical micelle concentration (CMC) measurements, and core flooding analysis were performed to ascertain the compatibility and recoverability of the cashew nutshell liquid derivatives on sandstone reservoirs. Interfacial tension was reduced from 10.46 to 1.66 mN/m at CMC of 1 g/L. Additional recovery factor and displacement efficiency of 12% OOIP and 32.5%, respectively, was achieved at laboratory temperature. The effect of temperature on residual oil recovery was determined by subjecting the oil displacement experiment to reservoir temperature of 80˚C, resulting in recovery factor and displacement efficiency of 9% OOIP and 25%, respectively.
Postoperative Adjuvant Hepatic Arterial Infusion Chemotherapy With FOLFOX in Hepatocellular Carcinoma With Microvascular Invasion: A Multicenter, Phase III, Randomized Study
Authors: Li Shao-Hua , Mei Jie , Cheng Yuan , Li Qiang , Wang Qiao-Xuan , Fang Chong-Kai , Lei Qiu-Cheng , Huang Hua-Kun , Cao Ming-Rong , Luo Rui , Deng Jing-Duo , Jiang Yu-Chuan , Zhao Rong-Ce , Lu Liang-He , Zou Jing-Wen , Deng Min , Lin Wen-Ping , Guan Ren-Guo , Wen Yu-Hua , Li Ji-Bin , Zheng Lie , Guo Zhi-Xing , Ling Yi-Hong , Chen Huan-Wei , Zhong Chong , Wei Wei , Guo Rong-Ping 
Published: December 2022

PURPOSE To report the efficacy and safety of postoperative adjuvant hepatic arterial infusion chemotherapy (HAIC) with 5-fluorouracil and oxaliplatin (FOLFOX) in hepatocellular carcinoma (HCC) patients with microvascular invasion (MVI). PATIENTS AND METHODS In this randomized, open-label, multicenter trial, histologically confirmed HCC patients with MVI were randomly assigned (1:1) to receive adjuvant FOLFOX-HAIC (treatment group) or routine follow-up (control group). The primary end point was disease-free survival (DFS) by intention-to-treat (ITT) analysis while secondary end points were overall survival, recurrence rate, and safety. RESULTS Between June 2016 and August 2021, a total of 315 patients (ITT population) at five centers were randomly assigned to the treatment group (n = 157) or the control group (n = 158). In the ITT population, the median DFS was 20.3 months (95% CI, 10.4 to 30.3) in the treatment group versus 10.0 months (95% CI, 6.8 to 13.2) in the control group (hazard ratio, 0.59; 95% CI, 0.43 to 0.81; P = .001). The overall survival rates at 1 year, 2 years, and 3 years were 93.8% (95% CI, 89.8 to 98.1), 86.4% (95% CI, 80.0 to 93.2), and 80.4% (95% CI, 71.9 to 89.9) for the treatment group and 92.0% (95% CI, 87.6 to 96.7), 86.0% (95% CI, 79.9 to 92.6), and 74.9% (95% CI, 65.5 to 85.7) for the control group (hazard ratio, 0.64; 95% CI, 0.36 to 1.14; P = .130), respectively. The recurrence rates were 40.1% (63/157) in the treatment group and 55.7% (88/158) in the control group. Majority of the adverse events were grade 0-1 (83.8%), with no treatment-related death in both groups. CONCLUSION Postoperative adjuvant HAIC with FOLFOX significantly improved the DFS benefits with acceptable toxicities in HCC patients with MVI.
Long-Term Morbidity and Mortality Among Survivors of Neuroblastoma Diagnosed During Infancy: A Report From the Childhood Cancer Survivor Study
Authors: Friedman Danielle Novetsky , Goodman Pamela J. , Leisenring Wendy M. , Diller Lisa R. , Cohn Susan L. , Howell Rebecca M. , Smith Susan A. , Tonorezos Emily S. , Wolden Suzanne L. , Neglia Joseph P. , Ness Kirsten K. , Gibson Todd M. , Nathan Paul C. , Weil Brent R. , Robison Leslie L. , Oeffinger Kevin C. , Armstrong Gregory T. , Sklar Charles A. , Henderson Tara O. 
Published: December 2022

PURPOSE To describe the risk of late mortality, subsequent malignant neoplasms (SMNs), and chronic health conditions (CHCs) in survivors of neuroblastoma diagnosed in infancy by treatment era and exposures. METHODS Among 5-year survivors of neuroblastoma in the Childhood Cancer Survivor Study diagnosed age < 1 year between 1970 and 1999, we examined the cumulative incidence of late (> 5 years from diagnosis) mortality, SMN, and CHCs (grades 2-5 and 3-5). Multivariable Cox regression models estimated hazard ratios (HRs) and 95% CIs by decade and treatment (surgery-alone v chemotherapy with or without surgery [C ± S] v radiation with or without chemotherapy ± surgery [R ± C ± S]) among survivors and between survivors and 5,051 siblings. RESULTS Among 1,397 eligible survivors, the 25-year cumulative incidence of late mortality was 2.1% (95% CI, 1.3 to 3.9) with no difference by treatment era. Among 990 participants who completed a baseline survey, fewer survivors received radiation in more recent eras (51.2% 1970s, 20.4% 1980s, and 10.1% 1990s; P < .001). Risk of SMN was elevated only among individuals treated with radiation-containing regimens compared with surgery alone (HR[C ± S], 3.2 [95% CI, 0.9 to 11.6]; HR[R ± C ± S], 5.7 [95% CI, 1.2 to 28.1]). In adjusted models, there was a 50% reduction in risk of grade 3-5 CHCs in the 1990s versus 1970s (HR, 0.5 [95% CI, 0.3 to 0.9]; P = .01); individuals treated with radiation had a 3.6-fold risk for grade 3-5 CHCs (95% CI, 2.1 to 6.2) versus those treated with surgery alone. When compared with siblings, risk of grade 3-5 CHCs for survivors was lowest in the most recent era (HR[1970s], 4.7 [95% CI, 3.4 to 6.5]; HR[1980s], 4.6 [95% CI, 3.3 to 6.4]; HR[1990s], 2.5 [95% CI, 1.7 to 3.9]). CONCLUSION Neuroblastoma survivors treated during infancy have a relatively low absolute burden of late mortality and SMN. Encouragingly, risk of CHCs has declined in more recent eras with reduced exposure to radiation therapy.
George Floyd in Papua: Image-Events and the Art of Resonance
Authors: Strassler Karen 
Published: December 2022

Abstract
This article offers an introduction to the “image-event” as both concept and method through a focus on the circulation of images around the killing of George Floyd. It examines how these images reverberated and resonated in West Papua, a restive region of Indonesia that has been the site of a long-standing separatist movement. It critically examines a celebratory media discourse that sees the US-based Black Lives Matter movement as expanding outward to spark similar movements elsewhere, a logic that reiterates long-standing colonialist narratives that figure places like Papua as backwaters belatedly receiving and imitatively taking up ideas that flow from the metropole outward. Questioning such assumptions, the article suggests that attention to image-events and the art of resonance can better reveal the ways that long-standing global asymmetries affect the flow of images and the course of political action.
Three Histories and Seven Lives: Investigating the Archives of South Indian Photo Studios, Tamil Nadu, 1880–1980
Authors: Headley Zoé E. 
Published: December 2022

AbstractThis article explores the diffusion and productions of commercial studio photography in South India (Tamil Nadu) from the time the first Indian-run studios opened in the 1880s up to the demise of analog photography—and thereby of many family-run studios—a century later. The particular focus of the article is on research carried out to constitute the stars.archive (Studies in Tamil Studio Archives and Society), the first digital archive of Tamil studio photography, which includes around forty-two thousand photographic images digitized inside studios, private homes, and secondhand shops all over Tamil Nadu. Through examination of the archive, the article suggests that a history of photography in this region needs to attend more closely to the specificities of appropriation of the photographic apparatus and its social uses by sourcing empirical data outside institutional archives. A closer examination of the content of the stars.archive reveals the diversification over time of the social uses of studio photography, far beyond the ubiquitous “studio portrait.”