bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differential responses of soybean genotypes to off‐target dicamba damage
Authors: Canella Vieira Caio , Zhou Jing , Cross Cory , Heiser James W. , Diers Brian , Riechers Dean E. , Zhou Jianfeng , Hernandez Jarquin Diego , Nguyen Henry , Shannon J. Grover , Chen Pengyin 
Published: April 2022

AbstractSince the commercialization and widespread adoption of dicamba‐tolerant (DT) soybean cultivars across the United States, numerous cases of off‐target damage to non‐DT soybean have been reported. Soybean is naturally highly sensitive to dicamba, a synthetic auxin herbicide. Previous studies have focused on understanding the impact of growth stage, dosage, frequency, and duration of dicamba exposure on the severity of symptomology and yield loss. To date, little research has investigated the effect of genetic components in the observed responses. Therefore, this study was conducted to estimate yield losses caused by prolonged off‐target dicamba exposure and to identify genotypes with varying responses to off‐target damage. A total of 553 soybean genotypes derived from 239 unique biparental populations were evaluated in nine environments over 3 yr. A yield penalty of 8.8% was observed for every increment in damage score on a 1–4 scale with losses as high as 40%. Although the interaction between damage and maturity group (MG) significantly affected yield, genotypes showing the most tolerance had similar yields independent of their MG. This indicated that natural tolerance to off‐target dicamba may be conferred by physiological mechanisms other than the length of the recovery window. Given the widespread adoption of DT systems and potential yield losses in non‐DT soybean genotypes, identification of non‐DT soybean genotypes with higher tolerance to off‐target dicamba may sustain and improve the production of other non‐DT herbicide soybean production systems, including the niche markets of organic and conventional soybean.
Corporate sustainability and analysts' earnings forecast accuracy: Evidence from environmental, social and governance ratings
Authors: Luo Kun , Wu Sirui 
Published: April 2022

AbstractWe investigate the effect of corporate sustainability on analysts' forecast accuracy. Specifically, this paper documents how financial analysts respond to environmental, social and governance factors (hereinafter ESG) in earnings forecasts. Using a novel dataset from the Bloomberg ESG ratings, we find that ESG ratings increase analysts' forecast accuracy by reducing information risks and operation risks. The results are robust to a series of robustness checks, including propensity score matching, Heckman two‐stage estimation, staggered difference‐in‐differences (DID), placebo test, firm and year fixed effects and alternative proxies. The effect of ESG ratings on analysts' forecast accuracy is more pronounced for firms audited by accounting firms with low industry expertise and for firms tracked by analysts with low industry expertise. This paper responds to the calls for more research on ESG ratings and analysts' earnings forecast accuracy and provides implications that ESG assurance can effectively improve the quality of nonfinancial information of a company. In addition, the paper is valuable for policymakers to improve the ESG disclosure system.
Automation and Microfluidics for the Efficient, Fast, and Focused Reaction Development of Asymmetric Hydrogenation Catalysis
Authors: van Putten Robbert , Eyke Natalie S. , Baumgartner Lorenz M. , Schultz Victor L. , Filonenko Georgy A. , Jensen Klavs F. , Pidko Evgeny A. 
Published: April 2022

AbstractAutomation and microfluidic tools potentially enable efficient, fast, and focused reaction development of complex chemistries, while minimizing resource‐ and material consumption. The introduction of automation‐assisted workflows will contribute to the more sustainable development and scale‐up of new and improved catalytic technologies. Herein, the application of automation and microfluidics to the development of a complex asymmetric hydrogenation reaction is described. Screening and optimization experiments were performed using an automated microfluidic platform, which enabled a drastic reduction in the material consumption compared to conventional laboratory practices. A suitable catalytic system was identified from a library of RuII‐diamino precatalysts. In situ precatalyst activation was studied with 1H/31P nuclear magnetic resonance (NMR), and the reaction was scaled up to multigram quantities in a batch autoclave. These reactions were monitored using an automated liquid‐phase sampling system. Ultimately, in less than a week of total experimental time, multigram quantities of the target enantiopure alcohol product were provided by this automation‐assisted approach.
Highly Robust Rhenium(I) Bipyridyl Complexes Containing Dipyrromethene‐BF2 Chromophores for Visible Light‐Driven CO2 Reduction
Authors: Qiu Li‐Qi , Yang Zhi‐Wen , Yao Xiangyang , Li Xiao‐Yang , He Liang‐Nian 
Published: April 2022

AbstractNew rhenium bipyridyl complexes with dipyrromethene‐BF2 chromophores (A‐ReBDP‐CZ, A‐ReBDP2, ReBDP‐CZ, and ReBDP2) were developed for highly efficient photocatalytic carbon dioxide (CO2) reduction to carbon monoxide (CO). These catalysts consisted of two moderate electron‐deficient groups (dipyrromethene‐BF2, BDP) as the visible‐light‐harvesting antenna as well as both electron donor (N‐phenylcarbazole, CZ) and acceptor (BDP) on Re bipyridyl framework. Among ReBDP‐CZ and ReBDP2 complexes, the ReBDP2 incorporating two electron‐deficient BDP chromophores had a longer‐lived photoexcited state (182.4 μs) and a twofold enhanced molar absorption coefficient (ϵ=157000 m−1 cm−1) compared with ReBDP‐CZ. Thus, ReBDP2 achieved the superior photocatalytic reactivity and stability with a CO turnover number (TONCO) value as high as 1323 and quantum yield (ΦCO) up to 55 %, which was the most excellent photocatalysis efficiency among the single‐active‐site Re catalysts without additional photosensitizer. Furthermore, the acetylene‐bridged linker was detrimental to the photoactivity and durability of the catalyst. In brief, two BDP‐based Re bipyridyl systems with outstanding catalytic performance and significant visible‐light‐harvesting capabilities in the solar spectrum offer a promising strategy for solar‐to‐fuel conversion schemes.
A ternary memristor full adder based on literal operation and module operation
Authors: Lin Mi , Han Qi , Luo Wenyao , Wang Xuliang , Chen Junjie , Lyu Weifeng 
Published: April 2022

AbstractA ternary memristor full adder is designed based on the literal operation and module‐3 plus operation. Literal operation and module‐3 plus operation are the important operations in the tri‐valued algebra system. Multiple‐valued logic can increase the amount of information carried by the signals and reduce the number of devices and connections. The combination of multiple‐valued logic and memristor is an exploration of new devices and new structures. The novel ternary memristor full adder owns the advantage of simpler structure without decoding units to convert ternary signals to binary at the terminals, and all the signals operated by the circuit are ternary. Compared with the traditional ternary full adder, the number of devices and the power consumption are greatly reduced. Simulation results of different memristor models verified the correctness and applicability of the circuit design. It provides a new idea for the design method of memristor circuits, especially multiple‐valued memristors.
A case of walled‐off necrosis extending into the pelvic cavity successfully treated by endoscopic necrosectomy using a lumen‐apposing metal stent
Authors: Morita Makoto , Yokota Tomoyuki , Yano Ryo , Amano Michiko , Ochi Hironori , Azemoto Nobuaki , Mashiba Toshie , Joko Kouji 
Published: April 2022

AbstractA 31‐year‐old man developed massive walled‐off necrosis extending into the pelvic cavity following severe acute alcoholic pancreatitis. Endoscopic ultrasound‐guided fistula drainage was performed using a lumen‐apposing metal stent, but this was insufficiently effective, and endoscopic necrosectomy was also performed, after which the patient improved. Percutaneous drainage and surgery are other options for the treatment of walled‐off necrosis extending into the pelvic cavity, but a valuable case in which the patient improved with endoscopic treatment alone is presented.
Polypyrimidine tract binding protein 1 regulates the activation of mouse CD8 T cells
Authors: D'Angeli Vanessa , Monzón‐Casanova Elisa , Matheson Louise S. , Gizlenci Özge , Petkau Georg , Gooding Clare , Berrens Rebecca V. , Smith Christopher W. J. , Turner Martin 
Published: April 2022

AbstractThe RNA‐binding protein polypyrimidine tract binding protein 1 (PTBP1) has been found to have roles in CD4 T‐cell activation, but its function in CD8 T cells remains untested. We show it is dispensable for the development of naïve mouse CD8 T cells, but is necessary for the optimal expansion and production of effector molecules by antigen‐specific CD8 T cells in vivo. PTBP1 has an essential role in regulating the early events following activation of the naïve CD8 T cell leading to IL‐2 and TNF production. It is also required to protect activated CD8 T cells from apoptosis. PTBP1 controls alternative splicing of over 400 genes in naïve CD8 T cells in addition to regulating the abundance of ∼200 mRNAs. PTBP1 is required for the nuclear accumulation of c‐Fos, NFATc2, and NFATc3, but not NFATc1. This selective effect on NFAT proteins correlates with PTBP1‐promoted expression of the shorter Aβ1 isoform and exon 13 skipped Aβ2 isoform of the catalytic A‐subunit of calcineurin phosphatase. These findings reveal a crucial role for PTBP1 in regulating CD8 T‐cell activation.
Calix[8]quinone: A new promising macrocyclic molecule as an efficient organic cathode in lithium ion batteries with a highly‐concentrated electrolyte
Authors: Huang Weiwei , Liu Shuai , Li Chaobo , Lin Yilin , Hu Pandeng , Sun Zhaopeng , Zhang Qichun 
Published: April 2022

AbstractOrganic cathode materials have potential applications in rechargeable batteries due to their several advantages such as high specific capacity, flexible designability, plentiful raw materials, environmental friendliness, and renewability. However, their high solubility in organic electrolytes strongly impedes the further research progress. Thus, it is highly desirable to develop some new strategies to address this issue. Herein, we report one method to address this dissolution issue by increasing molecular weight without reducing theoretical capacity, where a novel Calix[8]quinone (C8Q) with 8p‐benzoquinone units connected by methylene groups was designed and prepared in a good yield (total: 23%). C8Q exhibits higher cycle stability (268 mAh g−1) in lithium‐ion batteries (LIBs) compared to the same series of substances Calix[4]quinone (C4Q, 30 mAh g−1) and Calix[6]quinone (C6Q, 207 mAh g−1) after 100 cycles at 0.2 C. Moreover, C8Q shows better electrochemical performance in 4.2 M LiTFSI‐AN highly‐concentrated electrolyte with special aggregate structure configured with high‐dissociation salt LiTFSI and low‐viscosity solvent acetonitrile (AN), namely, C8Q possesses high capacity (340 mAh g−1after 100 cycles at 0.2 C), superior rate ability (440 mAh g−1at 0.1 C and 167 mAh g−1at 5 C), and ultra‐long cycle life (220 mAh g−1after 1000 cycles at 0.5 C). This work could provide a promising strategy to address the dissolution issue of organic electrode materials in organic electrolyte.image
Weight‐loss interventions for improving emotional eating among adults with high body mass index: A systematic review with meta‐analysis and meta‐regression
Authors: Chew Han Shi Jocelyn , Lau Siew Tiang , Lau Ying 
Published: April 2022

AbstractObjectivesTo evaluate the effectiveness of weight‐loss interventions on emotional eating among adults with high body mass index (BMI).MethodsA systematic review, meta‐analysis and meta‐regression were performed on randomized controlled trials published from inception until 19 March 2021.ResultsThirty‐one studies were included, representing 1203 participants with mean ages ranging from 21.8 to 57.3 years old and BMI 27.2–43.5 kg/m2. We found small‐to‐medium interventional effects on emotional eating (n = 18; Hedges' g = 0.22; p = 0.01, I2 = 61.7%), uncontrolled eating (n = 16; Hedges' g = 0.46; p < 0.001, I2 = 71.6%) and cognitive restraint (n = 18; Hedges' g = 0.42; p < 0.001, I2 = 75.8%). Small‐to‐medium interventional effects were only found for emotional eating (n = 8; Hedges' g = 0.45; p = 0.02, I2 = 74.3%) 3‐month post‐intervention, and on BMI (n = 4; Hedges' g = 0.43; p < 0.05, I2 = 33.4%) and weight (n = 6; Hedges' g = 0.36; p < 0.01, I2 < 10.4%) 12‐month post‐intervention. Age, male proportion, baseline BMI, attrition rate and intervention length were not significant moderators of the heterogeneity between studies.ConclusionInterventions improved emotional eating and weight loss along a year‐long trajectory.
A privacy‐preserving mechanism for social mobile crowdsensing using game theory
Authors: Esmaeilyfard Rasool , Esmaili Reyhaneh 
Published: April 2022

AbstractSmartphones and mobile networks have created a new paradigm called mobile crowdsensing for data gathering and processing about a large‐scale phenomenon. This paradigm's development allows untrustworthy people to gather large amounts of information over time from the reported events. In this regard, mobile crowdsensing increases the possibility of violating users' privacy. Recently, social communication has added potential capabilities to mobile crowdsourcing environments. Based on these social communications, this article presents an analysis of user's interactions for privacy‐preserving using a signaling game with a dynamic approach and incomplete information. First, the analysis identifies the pure‐strategy profiles and mixed‐strategy profiles and the user's best strategy for accepting access requests in a single time slot. This analysis is then extended into a dynamic multistage game. In this analysis, users' beliefs about the violation of their privacy are analyzed and updated at every stage. As a result, the best response from users will be determined. Following this analysis, a mechanism is presented for privacy‐preserving in social mobile crowdsensing. The experimental results have also indicated the success of the proposed method in dealing with different types of user interaction.
Doppler estimation based on linear interpolation for underwater acoustic communication
Authors: Li Shibao , Wang PengHao , Wang Shuqi , Cong Yujie , Liu Jianhang , Cui Xuerong 
Published: April 2022

AbstractIn this article, we develop a Doppler estimation approach based on linear interpolation for underwater acoustic (UWA) OFDM system. Linear interpolation is used to achieve the resampling of the received signal. By interpolating the sampled signal with different compensation factors at the receiving end, the repeating structure of the CP‐OFDM symbol is used to maximize the correlation value at the fixed window to obtain the estimated value of the Doppler factor. The fixed window is determined based on the length of the cyclic prefix and the maximum path delay. In addition, we deduced the expression of the received discrete sequence to perform correlation operations after interpolation, which is the theoretical basis of our proposed algorithm. Moreover, in order to reduce the number of iterations, which means computational complexity in this algorithm, we recommend using the dichotomy to quickly find the maximum correlation value. Simulation proves that the proposed algorithm perform better than other CP‐OFDM‐based time‐domain autocorrelation algorithms.
Anti‐Black Racism as a Chronic Condition
Authors: Sederstrom Nneka , Lasege Tamika 
Published: April 2022

AbstractBecause America has a foundation of anti‐Black racism, being born Black in this nation yields an identity that breeds the consequences of a chronic condition. This article highlights several ways in which medicine and clinical ethics, despite the former's emphasis on doing no harm and the latter's emphasis on nonmaleficence, fail to address or acknowledge some of the key ways in which physicians can—and do—harm patients of color. To understand harm in a way that can provide real substance for ethical standards in the practice of medicine, physicians need to think about how treatment decisions are constrained by a patient's race. The color of one's skin can and does negatively affect the quality of a person's diagnosis, promoted care plan, and prognosis. Yet racism in medicine and bioethics persist—because a racist system serves the interests of the dominant caste, White people. As correctives to this system, the authors propose several antiracist commitments physicians or ethicists can make.
From a Reckoning to Racial Concordance: A Strategy to Protect Black Mothers, Children, and Infants
Authors: Johnson Nia 
Published: April 2022

AbstractThe grave state of health among Black Americans warrants reexamination of how to mitigate health disparities. In this commentary, which responds to the important concerns Nneka Sederstrom and Tamika Lasege raise in “Anti‐Black Racism as a Chronic Condition,” I argue that the use of racial concordance for Black patients can be a step toward reducing mortality rates and health care negligence for Black people. Racial concordance involves aligning patients with providers of their same race to mitigate implicit bias. Racial concordance is imperfect, but the unjust rates of mortality and other adverse health outcomes that Black Americans face each day in health care facilities may warrant taking seriously this solution.
Exploring the misalignment on the value of further research between payers and manufacturers. A case study on a novel total artificial heart
Authors: Federici Carlo , Pecchia Leandro 
Published: April 2022

AbstractPayers and manufacturers can disagree on the appropriate level of evidence that is required for new medical devices, resulting in high societal costs due to decisions taken with sub‐optimal information. A cost‐effectiveness model of a hypothetical total artificial heart was built using data from the literature and the (simulated) results of a pivotal study. The expected value of perfect information (EVPI) was calculated from both the payer and manufacturer perspectives, using net monetary benefit and the company's return on investment respectively. A function was also defined, linking effectiveness to market shares. Additional constraints such as a minimum clinical difference or maximum budget impact were introduced into the company's decisions to simulate additional barriers to adoption. The difference in the EVPI between manufacturers and payers varied greatly depending on the underlying decision rules and constraints. The manufacturer's EVPI depends on the probability of being reimbursed, the uncertainty on the (cost‐)effectiveness of the technology, as well as other parameters relating to initial investments, operating costs and market dynamics. The use of Value of information for both perspectives can outline potential misalignments and can be particularly useful to inform early dialogs between manufacturers and payers, or negotiations on conditional reimbursement schemes.
Surgical technique for superselective neck dissection under local anesthesia in recurrent head and neck cancer
Authors: Kobayashi Kenya , Ikeda Atsuo , Matsumoto Yoshifumi , Matsumura Satoko , Omura Go , Eguchi Kohtaro , Sakai Azusa , Ito Akiko , Matsumoto Fumihiko , Yoshimoto Seiichi 
Published: April 2022

AbstractThe aim of this paper is to describe a safe and effective surgical technique for neck dissection under local anesthesia. An increasing number of patients cannot undergo general anesthesia due to systemic complication arising from old age. Moreover, the long‐term survival of patients with recurrent or metastatic cancer due to advances in chemotherapy has increased the necessity of neck dissection under local anesthesia. Appropriate pain control and selection of medical devices are important factors for success of the surgery under local anesthesia. In addition to the usual subcutaneous infiltration anesthesia for pain control, nerve blocks for each cervical nerve encountered during surgery are extremely effective. Since muscle relaxants are not available, sharp devices such as knife or scissors, instead of electric scalpel, should be used to prevent unexpected muscle contractions caused by electric current. This video presents well‐proven techniques and technical tips for superselective neck dissection under local anesthesia.
B‐cell activating factor (BAFF), BAFF promoter and BAFF receptor allelic variants in hepatitis C virus related Cryoglobulinemic Vasculitis and Non‐Hodgkin's Lymphoma
Authors: Gragnani Laura , Lorini Serena , Marri Silvia , Rattotti Sara , Madia Francesco , Zibellini Silvia , Monti Monica , Basile Umberto , Di Stasio Enrico , Libra Massimo , Arcaini Luca , Zignego Anna Linda 
Published: April 2022

AbstractCryoglobulinemic Vasculitis (CV) is an autoimmune/lymphoproliferative disorder associated with HCV infection that in 5%–10% of cases evolves into a B cell Non‐Hodgkin's Lymphoma (NHL). B‐cell activating factor (BAFF) is a key regulator in B‐cell development and survival. Particular genetic variants are responsible for BAFF signaling impairment in autoimmune and neoplastic diseases. We evaluated BAFF and BAFF‐receptor (BAFF‐R) polymorphisms in order to determine if they predispose to HCV‐related CV and NHL. The analysis was performed on 416 HCV‐chronically infected patients: 136 HCV without signs/symptoms of lymphoproliferations/autoimmunity (HCV), 166 HCV with CV (HCV‐CV) and 114 HCV with NHL (HCV‐NHL). Rs9514828 SNP on BAFF promoter, rs61756766 on BAFF‐R and rs12428930 on the BAFF gene were evaluated by Real‐Time PCR. Concerning rs9514828, the frequency of C/T genotype was significantly higher in HCV‐CV than in HCV. The difference in the distribution of the T/T mutant genotype in HCV‐CV compared to HCV was significant as well as the distribution of C/T and T/T genotype in HCV‐NHL versus HCV. T minor allele was more frequent in HCV‐NHL and HCV‐CV than in HCV. The distribution of C/T + T/T (for the dominant model of penetrance C/T + T/T vs. C/C) was significantly higher in HCV‐CV and HCV‐NHL than in HCV. Genotyping of rs61756766 on BAFF‐R coding gene, revealed C/T heterozygosis at a frequency of 11% in HCV‐NHL versus 3% in HCV. The T minor allele frequency was higher in HCV‐NHL than in HCV. No differences emerged by genotyping rs12428930 SNP on BAFF coding gene. Our results reinforce the hypothesis that BAFF/BAFF‐R genetic pattern has a role in the pathogenesis of HCV‐related lymphoproliferations. BAFF/BAFF‐R variants could identify a risk haplotype for HCV related CV and NHL and a BAFF/BAFF‐R genetic profile assessment could potentially contribute to tailoring anti‐BAFF therapy by identifying patients with BAFF alterations in which the treatment could be more beneficial.