bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS PENGARUH RASIO KEUANGAN TERHADAP PERTUMBUHAN LABA Sudi Pada perusahaan non bank yang tergabung dalam kelompok LQ45 yang terdaftar di Bursa Efek Indonesia periode 2010- 2014”
Authors: Pangaribuan Hasudungan - 
Published: April 2022

ABSTRAK Tujuan dari penelitian ini adalah menganalisis pengaruh variabel Working Capital to Total Asset (WCTA), Current Liabilities To Inventory (CLI), Operating Income to Total Assets (OITL), Total Asset Turnover (TAT), Net Profit Margin (NPM) dan Gross Profit Margin (GPM) terhadap pertumbuhan laba.Data diperoleh dengan metode purposive sampling dengan kriteria (1) Perusahaan non bank yang terdaftar di Bursa Efek Indonesia (BEI) yang masuk ke dalam penghitungan indeks LQ45 periode Agustus 2014 sampai dengan Januari 2015, (2) Perusahaan non bank yang konsisten ada selama periode penelitian (2010 sampai dengan 2014), (3) Perusahaan non bank yang terdaftar di Bursa Efek Indonesia (BEI) yang menyediakan data laporan keuangan selama periode penelitian (2010 sampai dengan 2014) dan (4) Perusahaan non bank tidak menghasilkan laba negatif selama periode 2010 sampai dengan 2014, dan (5) Perusahaan non bank yang data-data keuangannya menghasilkan distribusi normal (tahun 2010 sampai dengan 2014).Hasil analisis menunjukkan bahwa data-data yang digunakan didalam penelitian ini telah memenuhi asumsi klasik, yang meliputi: tidak terjadi gejala multikolinearitas, tidak terdapat autokorelasi, tidak terjadi gejala heteroskedastisitas, dan data terdistribusi normal. Dari hasil analisis regresi menunjukkan bahwa variabel Working Capital to Total Asset (WCTA), variabel Total Asset Turnover (TAT), Net Profit Margin (NPM) secara parsial berpengaruh positif signifikan terhadap pertumbuhan laba dan variabel Current Liability to Inventory (CLI) secara parsial berpengaruh negatif signifikan terhadap pertumbuhan laba. Sedangkan, Operating Income to Total Assets (OITL) dan Gross Profit Margin (GPM) tidak berpengaruh signifikan terhadap pertumbuhan laba. Keenam variabel yang digunakan dalam penelitian ini (WCTA, CLI, OITL, TAT, NPM dan GPM) secara bersama-sama berpengaruh signifikan terhadap pertumbuhan laba. Kemampuan prediksi dari keenam variabel secara simultan adalah sebesar 0,000.Kata kunci: Working Capital to Total Asset (WCTA), Current Liabilities To Inventory (CLI), Operating Income to Total Assets (OITL), Total Asset Turnover (TAT), Net Profit Margin (NPM), Gross Profit Margin (GPM) dan pertumbuhan laba.
PENGARUH BIAYA PROMOSI TERHADAP PENINGKATAN VOLUME PENJUALAN PADA CV SUSU CERIA KIDS DI KOTA DEPOK
Authors: Irmal Irmal - 
Published: April 2022

ABSTRAK Tujuan penelitian ialah untuk mengetahui biaya promosi, jumlah penjualan dan pengaruh biaya promosi (sebagai variabel X) terhadap penjualan (sebagai variabel Y) pada CV Susu Ceria Kids di Kota Depok. Rancangan hipotesis penelitian ialah H0:rxy=0, bahwa tidak terdapat pengaruh signifikan antara x dan y; dan Ha:rxy≠0, bahwa terdapat pengaruh signifikan antara x dan y. Pengujian hipotesis dilakukan dengan membandingkan nilai t-hitung (th) koefisien korelasi x dan y (rxy) dengan nilai kritis t-tabel (tt) maka H0 ditolak, Ha diterima dan sebaliknya apabila th<tt maka H0 diterima, Ha ditolak. Metode penelitian yang digunakan pada tulisan ini ialah metode kuantittaif asosiatif (korelatif) sedangkan pengolahan data kuantitatif dengan menggunakan analisis statistik. Populasi dan sampel penelitian ini ialah data laporan keuangan CV Susu Ceria Kids periode tahun 2012 sampai dengan tahun 2016.Berdasarkan hasil analisis korelasi pearson’s product moment diperoleh koefisien korelasi rxy =0,867 dengan koefisien determinan Kd= 82,63%, uji hipotesis;th=3.88>tt=2.57 (dua arah) dan persamaan regresi y=-341.14 + 8.46 X. Ini dapat dijelaskan bahwa nilai konstanta dari persamaan regresi di atas, yakni sebesar 341.14, nilai konstanta merupakan nilai konstan atau nilai tetap jika diasumsikan biaya promosi bernilai 0, sehingga apabila diasumsikan demikian, maka penjualan produk tetap pada 341.14, selain nilai konstanta, dari persamaan regresi di atas juga diketahui nilai koefisien regresi, yaitu sebesar 8.46, nilai ini menggambarkan besarnya kenaikan biaya promosi naik Rp.1.000.000, maka penjualan naik Rp. 8.460.000 Kata Kunci: Biaya Promosi terhadap penjualan
“PENGARUH TASK IDENTITY, TASK SIGNIFICANCE, DAN KEPUASAN KERJA TERHADAP KINERJA GURU SMP AL AMANAH”
Authors: Rahmanita Fika - 
Published: April 2022

ABSTRAK Tujuan utama dari penelitian ini adalah untuk mengetahui hubungan antara task identity, task significance, kepuasan kerja, terhadap kinerja.Metode survei digunakan, dengan purposive sampling dipilih sebagai teknik pengambilan sampel. Sampel terdiri dari 24 responden. Dimana variabel dalam penelitian bisa memperkuat atau justru menjadi kelemahan yang berperan untuk hubungan antara antara task identity, task significance, kinerja, dan kepuasan kerja. Kemudian, variabel yang memiliki hubungan terkuat adalah faktor utama yang perlu ditingkatkan untuk meningkatkan kinerja.Hasil penelitian menunjukkan bahwa task identity, task significance dan kepuasan kerja mempengaruhi kinerja, namun task identity dan task significance tidak memiliki pengaruh signifikan terhadap kepuasan kerja. Task identity memiliki pengaruh paling besar terhadap kinerja. Oleh karena itu untuk meningkatkan kinerja guru SMP Al Amanah, perlu ditingkatkan faktor-faktor yang mempengaruhi task identity. Kata kunci: task identity, task significance, kepuasan kerja, kinerja
Application of Standardized Nursing in the Perioperative Period of Patients with Idiopathic Scoliosis
Authors: Liang Weijing 
Published: April 2022

Objective — To explore the standardized nursing program for idiopathic scoliosis deformity correction under general anesthesia during perioperative period. Methods — Retrospective analysis 28 patients with adolescent idiopathic scoliosis (AIS) as the research object admitted from 2020 July to August 2021. The nursing plan formulated in the operating room of our hospital was strictly implemented, patients and surgical risks were comprehensively evaluated before surgery, the operating room, surgical instruments and intraoperative drugs were carefully prepared, the operation was performed with strict aseptic techniques, the surgical medical team cooperated skillfully, and the changes of the condition were closely observed after surgery. Results — Operations were smoothly conducted for all the 28 patients with full recovery. The patients were proved without presence of symptoms of skin pressure injury, nervous system injury, serious timeout, postoperative paralysis, hemorrhagic shock and other serious adverse events. Conclusions — Posterior orthopaedic surgery for scoliosis is proved to be difficult for operation with long duration and high risks. There are many risk factors in perioperative nursing. According to standardized and specialized nursing programs, strict intervention throughout the perioperative period can improve the quality of nursing in the operating room, which can improve the efficiency of surgery, reduce the risk of surgery, ensure the safety of patients, and promote the rapid recovery of patients.
Gestor em saúde na SES Tocantins: Avaliação de conhecimentos e competências
Authors: Barbosa César Martins , Pinto Isabela Cardoso de Matos 
Published: April 2022

Trata-se de um estudo exploratório descritivo, cujo objetivo principal é a caracterização do perfil do gestor em saúde, através do mapeamento dos conhecimentos e competências. No que diz respeito ao conhecimento e aplicação das leis que regem o processo licitatório, 93% dos entrevistados conhecem as leis de licitação e as utilizam no seu dia a dia de trabalho, enquanto 6,7% têm conhecimento sobre o assunto, porém, não o utilizam no desempenho de suas tarefas. Em relação às bases legais do SUS é conhecida por apenas 73,3% da amostra. Os dados demonstram que 80% dos profissionais conhecem a LRF. Sobre a LOA, apenas 40% dos profissionais entrevistados afirmam conhecê-la. Quando os sujeitos foram indagados sobre o seu conhecimento em relação à PPA, apenas 60% disseram conhecer o instrumento. O SIOPS é conhecido por apenas 40% do grupo. 86,7% dos profissionais conhecem o RAG. Já a PPI é conhecida por 66,7% dos profissionais entrevistados. Quanto ao PS, somente, 66,7% afirmam conhecê-lo, o PES é conhecido por 86,7% dos entrevistados. Indagados sobre a agenda de prioridades, 66,7% afirmam conhecê-la. Algumas competências gerenciais são muito estimuladas, outras não. Dentre as estimuladas, estão: abertura para mudanças, ética e profissionalismo e consciência da qualidade, com 46,7% dos entrevistados respondendo de forma positiva a estes estímulos. Outras competências como atuação de forma preventiva e expressar-se de modo crítico (40% cada) e conhecimento sobre as políticas de saúde (53,3%). Além disso, vê-se: trabalho em equipe (40%), comunicação (46,7%) e visão estratégica (33,3%). Outras competências são razoavelmente estimuladas: iniciativa e criatividade; e capacidade de liderar pessoas (26,7% cada). 40% dos gestores não se sentem estimulados a participar dos processos decisórios. Ao final do estudo, percebeu-se a influência do perfil dos gestores no aperfeiçoamento das práticas de gestão, já que mostrou as potencialidades e os desafios enfrentados e servirá de base para o processo de qualificação permanente dos profissionais envolvidos na gestão, traduzida em ações mais efetivas e eficientes, proporcionadas pelo conhecimento e uso dos mecanismos de apoio ao gerenciamento do SUS.
Dos documentos inéditos: Las escrituras del Banco de Tacna en los 150 años de su fundación
Authors: Quenta Loza Paolo Mario , Villanueva Quispe Alonso Anibal , Peralta Casani Pedro Pablo 
Published: April 2022

El Banco de Tacna fue una sociedad y/o compañía de carácter privado que inició sus operaciones siete años antes de la guerra con Chile, para facilitar las actividades comerciales que articulaban a Tacna y Arica con el vecino país de Bolivia, principalmente.
Además de estas operaciones, el Banco de Tacna realizaba empréstitos para la ejecución de obras públicas en la ciudad, como ocurrió con la refacción del hospital San Ramón, el cual tuvo que ser demolido a consecuencia de las torrenciales lluvias de 18774. Dicha labor continuaría durante la ocupación chilena, con préstamos para el ﬁnanciamiento de servicios públicos como la Empresa Eléctrica de Arica, así como empréstitos a empresas mineras, comerciales y a personas naturales con créditos hipotecarios (Ministerio de Relaciones Exteriores del Perú, 1927, pp. 405-406).
Durante la guerra con Chile, el Banco de Tacna brindó importantes servicios al Ejército del Sur, por los cuales se amplió el plazo para la circulación de sus billetes hasta después de culminado el conﬂicto bélico (Campubri, 1957, p.336). Luego de la batalla del Campo de la Alianza, el 26 de mayo de 1880, el ejército chileno inició la ocupación de Tacna e impuso contribuciones forzosas solidarias a los principales comerciantes y propietarios del departamento, entre los cuales se incluyó al Banco de Tacna con una cuota de cinco mil soles. Varios de sus accionistas tuvieron que pagar montos similares (Choque, 2009, p. 74).
En el periodo de la ocupación chilena de Tacna y Arica, el gobierno peruano usó los servicios del Banco de Tacna para el pago de las subvenciones a las escuelas, diarios peruanos y organizaciones de beneﬁcencia que funcionaban en ambas ciudades (González, 2017, p. 100). Incluso uno de sus gerentes, M. Artidoro Espejo, quien actuaba como un agente peruano encubierto, fue obligado a renunciar a su cargo por las autoridades chilenas, al conocerse sus actividades en las ciudades cautivas (Barreto, 1912, pp. 226-227).
POEMAS
Authors: Pomacosi Mansilla Jhener 
Published: April 2022

Lobo estepario
Un ser extraño, salvaje y sombríodía y noche recorre solitariotristes calles al borde del vacío
por donde arrastra en las horas finalessus pasos heridos, un lobo esteparioperdido entre nosotros, los normales.
Acecha desde lejos los hogares,los dignos no lo ven, no quieren verlo,conformes como están con sus azares.
El lobo los observa conmovido,porque nadie se atreve a conocerlomás allá de dos promesas y un olvido.
No pertenece a ellos su morada,no nació para vivir en manada.
Fire Behaviour of Treated Insulation Fibreboards and Predictions of its Future Development Based on Natural Aging Simulation
Authors: Osvaldová Linda Makovická , Mitrenga Patrik , Jancík Juraj , Titko Michal , Efhamisisi Davood , Košútová Katarína 
Published: April 2022

Wood-based composite materials represent a major fire safety risk. The application of water-based fire retardants (FR) can improve their fire performance. However, it is important to investigate the performance and stability of this protective system over time, as the ageing of materials and their exposure to climatic conditions can change their properties. The aim of this research work was to evaluate the effect of long-term aging on the combustibility of low-density insulation fibreboards (IFs) treated with a water-soluble flame retardant (FR) based on inorganic salts. Both natural and accelerated aging simulations were conducted. The accelerated aging simulation was performed using climate chambers. The FR efficiency was evaluated by the mass loss rate of the tested specimen. As expected, the FR formulation used significantly enhanced the fire properties of the boards, reaching maximum efficiency 6 months after its application onto the fibreboards. Markedly, after 4 years the efficiency of the investigated FR additive was considerably decreased with weight loss values comparable with the values of the untreated samples. Markedly, besides the apparent protection of wood fibers, the retardant did not prevent the gradual increase in mass loss rate of samples, it just slowed down the process. The main result of the study is to determine the effectiveness of the investigated FR on IFs during their natural ageing. The development of accurate datasets on the thermal behaviour of IFs is critical for their proper utilisation in building and construction applications.
Opioid Receptor Expression in Colorectal Cancer: A Nested Matched Case-Control Study
Authors: Belltall Amparo , Mazzinari Guido , Garrido-Cano Iris , Giner Francisco , Marí Anabel Marqués , Eroles Pilar , Argente-Navarro María Pilar , Cata Juan Pablo , Diaz-Cambronero Oscar 
Published: April 2022

BackgroundThere is growing interest in the possible effect of perioperative anesthetic management on the growth and spread of cancer. The impact of perioperative use of opioids on cancer recurrence remains controversial and an assessment cannot yet be established based on current publications. This study aimed to assess the differential expression of opioid receptors between healthy and tumor tissues in patients with stage II and III colorectal cancer undergoing elective surgery by immunohistochemistry (IHC).MethodsPropensity–score matched case–control study nested in a retrospective cohort of patients with stage II or III colorectal. The primary endpoint was the difference in µ–opioid receptor (MOR) expression measured by IHC between tumor and healthy tissue in subject with or without recurrence. Secondary endpoints were to evaluate the differences in Opioid Growth Factor Receptor (OGFR), cyclic adenosine monophosphate (cAMP) production and protein kinase A (PKA) in the matched sample and from a from samples of colorectal cancer stored in the Cancer Genome Atlas (TCGA) and Genotype Tissue Expression Project (GTEx).ResultsThere was a significant difference in MOR receptor (median 3 [intequartile range IQR: 1–3] and 0 [IQR: 0–2], P&lt;0.001) and OGFR receptor (median 6 [IQR: 5–6] and 2 [IQR: 1–2], P&lt;0.001) in tumor and control tissue respectively. However, there were no significant differences in cAMP nor PKA expression between both types of tissues and in expression in any of the analyzed variables by recurrence status. The MOR and OGFR expression data from TCGA database were similar to our sample size data with lower expression of MOR and higher expression of OGFR in tumoural samples with a skewed distribution for MOR expression in tumor tissue both in patients with and without recurrence.ConclusionIn patients with stage II and III colorectal cancer, overall expression of MOR and OGFR was significantly increased but was not different between previously matched patients with or without recurrence. No differences were found in the analyzed metabolic pathway of cAMP–PKA: These results were confirmed by an in silico analysis of samples from the TCGA–GTEx database.
Target-Based Virtual Screening of Natural Compounds Identifies a Potent Antimalarial With Selective Falcipain-2 Inhibitory Activity
Authors: Uddin Amad , Gupta Sonal , Mohammad Taj , Shahi Diksha , Hussain Afzal , Alajmi Mohamed F. , El-Seedi Hesham R. , Hassan Imtaiyaz , Singh Shailja , Abid Mohammad 
Published: April 2022

We employed a comprehensive approach of target-based virtual high-throughput screening to find potential hits from the ZINC database of natural compounds against cysteine proteases falcipain-2 and falcipain-3 (FP2 and FP3). Molecular docking studies showed the initial hits showing high binding affinity and specificity toward FP2 were selected. Furthermore, the enzyme inhibition and surface plasmon resonance assays were performed which resulted in a compound ZINC12900664 (ST72) with potent inhibitory effects on purified FP2. ST72 exhibited strong growth inhibition of chloroquine-sensitive (3D7; EC50 = 2.8 µM) and chloroquine-resistant (RKL-9; EC50 = 6.7 µM) strains of Plasmodium falciparum. Stage-specific inhibition assays revealed a delayed and growth defect during parasite growth and development in parasites treated with ST72. Furthermore, ST72 significantly reduced parasite load and increased host survival in a murine model infected with Plasmodium berghei ANKA. No Evans blue staining in ST72 treatment indicated that ST72 mediated protection of blood–brain barrier integrity in mice infected with P. berghei. ST72 did not show any significant hemolysis or cytotoxicity against human HepG2 cells suggesting a good safety profile. Importantly, ST72 with CQ resulted in improved growth inhibitory activity than individual drugs in both in vitro and in vivo studies.
Biohardening of Banana cv. Karpooravalli (ABB; Pisang Awak) With Bacillus velezensis YEBBR6 Promotes Plant Growth and Reprograms the Innate Immune Response Against Fusarium oxysporum f.sp. cubense
Authors: Saravanan R. , Nakkeeran S. , Saranya N. , Kavino M. , Ragapriya V. , Varanavasiappan S. , Raveendran M. , Krishnamoorthy A. S. , Malathy V. G. , Haripriya S. 
Published: April 2022

Graphical AbstractInduction of innate immune response and growth promotion in banana by B. velezensis against Foc.
Parecoxib Reduced Postsurgical Pain and Facilitated Movement More Than Patient Controlled Analgesia
Authors: Chiu Szu-Ching , Livneh Hanoch , Chen Jin-Cheng , Chang Chia-Ming , Hsu Honda , Chiang Tsay-I , Tsai Tzung-Yi 
Published: April 2022

BackgroundPostoperative pain management is an imperative issue for patients undergoing lumbar spinal fusion surgery. Delayed pain relief is associated with poor clinical outcomes. This study compared the effects of intravenously administered patient-controlled analgesia (PCA) with intravenous parecoxib, both commonly used methods for analgesic pain control after surgery.MethodsA non-randomized study was used to recruit 68 patients who were scheduled to receive lumbar spinal fusion surgery at a hospital in Taiwan from April through December of 2020. The group treated with parecoxib received an initial perioperative dose of parecoxib 40 mg during a 30-min period and then postoperative intravenous parecoxib at 40 mg per 12-h period, for 72 h. Those with PCA received morphine (0.4 mg/ml), droperidol (0.02 mg/ml), diphenhydramine (0.48 mg/ml), midazolam (0.02 mg/ml) and saline solution during the 3-day study course. Major outcomes, including visual scale pain score and Barthel index of activities of daily living, were collected via review of medical records at 4 times: 12, 24, 48 and 72 h after surgery. Comparative effects between two groups were assessed by the generalized estimating equations.ResultsAfter adjusting for potential confounders, the administration of parecoxib was associated with a significant decrease in pain scores and an increase in the Barthel Index, when compared with the PCA group (all p &lt; 0.05). Notably, both effects would maintain for 72 h after surgery.DiscussionThis is the first trial of which the authors are aware, that supports intravenous parecoxib as significantly enhancing patient mobility, in addition to having pain control efficacy, when compared with PCA. This study could be used as a reference when instituting interventions to improve the adaptation process and clinical prognoses after lumbar spinal fusion surgery.
How to Identify the Indications for Early Intervention in Acute Necrotizing Pancreatitis Patients: A Long-Term Follow-Up Study
Authors: Lu Jiongdi , Cao Feng , Zheng Zhi , Ding Yixuan , Qu Yuanxu , Mei Wentong , Guo Yulin , Feng Yu-Lu , Li Fei 
Published: April 2022

AimTo explore the indications for early intervention in patients with acute necrotizing pancreatitis (ANP) and evaluate the effect of early intervention on the prognosis of ANP patients.MethodsThe clinical data of patients with ANP who underwent general surgery at Xuanwu Hospital of Capital Medical University from January 1, 2014, to December 31, 2020, were collected retrospectively. The patients were followed-up every 6 months after discharge, and the last follow-up date was June 30, 2021.ResultsA total of 98 patients with ANP were included in the study. They were divided into an early group (n= 43) and a delayed group (n = 55) according to the first percutaneous drainage (PCD) intervention time (≤ 4 weeks or &gt; 4 weeks). Body temperature, inflammatory factor levels, and the number of patients with persistent organ failure (POF) were higher in the early group than in the delayed group. After the minimally invasive intervention, the body temperature and inflammatory factors of the two groups decreased significantly, most patients with POF improved, and the number of patients with reversal of POF in the early group was higher than that in the delayed group. Although the patients in the early group required more surgical intervention than those in the delayed group, there was no significant difference in mortality, incidence of postoperative complications, total length of hospital stay, or operation cost between the two groups. During long-term follow-up, there was no significant difference in the incidence of short-term and long-term complications and overall survival between the two groups.ConclusionsCompared to patients in the delayed group, early intervention did not affect the prognosis of patients with ANP. It may be more suitable for patients with ANP with deterioration [such as POF or infected pancreatic necrosis (IPN)].