bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rare cause of a resistant hypertension in a middle‐aged man: A case report
Authors: Marecek Renata , De Keyzer Eva , Taujan Georgiana , Baleanu Felicia , Rosu Mihaela , Papadopoulou Ioanna , Kosmopoulou Olga , Laura Iconaru 
Published: December 2022

AbstractCongenital adrenal hyperplasia associated to 11‐beta‐hydroxylase deficiency is a rare cause of secondary hypertension, usually discovered during childhood; however, a late diagnosis in adults has also been reported. Despite low cortisol levels, accumulated adrenal steroid precursors can activate the glucocorticoid receptor and thus protect the patient against adrenal crisis.
A child resides within a young adult: The first reported case of Alström syndrome in Bangladesh
Authors: Ahmed Mushfiq Newaz , Jabin Nowshin , Iktidar Mohammad Azmain , Arafat Shohael Mahmud , Khan Abed Hussain , Mitra Avrow , Chowdhury Romana 
Published: December 2022

AbstractA 32‐year‐old male case with short stature presented to us with audio‐visual impairment, obesity, impaired glucose tolerance, dyslipidemia, and hypogonadism. The single‐gene genetic analysis revealed an ALMS1 gene mutation. A diagnosis of ALMS was reached for meeting one major and four minor criteria.
A parallel algorithm for direct simulation of fluidized beds
Authors: Keating Johnwill , Minev Peter D. 
Published: December 2022

AbstractThis paper presents a parallel algorithm for massive direct simulations of fluidized beds. It is based on an implicit–explicit (IMEX) technique for efficient and stable time integration of the incompressible Navier–Stokes equations in a domain that fits the boundaries of the particles at any time moment. The only modelling element in the algorithm is the model for particle–particle collisions, which is of the so‐called soft‐sphere type. The parallel performance of this technique is comparable to the performance of fully explicit methods. The numerical simulations of fluidized beds show very realistic effects that demonstrate the relevance of the simulation approach.
Recent progress in the fabrication and processing of triboelectric yarns
Authors: Chen Qian , Akram Wasim , Cao Yuying , Ge Can , Lin Tong , Fang Jian 
Published: December 2022

AbstractTriboelectric nanogenerators (TENGs) have recently enjoyed rapid development due to their easy fabrication, stable outputs, and wide range of applications. By combining conventional textiles with TENGs, textile‐based TENGs (t‐TENGs) can be employed with wearable devices and smart textiles. The t‐TENGs with a yarn structure, triboelectric yarns, can be directly used to conduct energy conversion and be processed into other energy‐harvesting textile structures due to their lightweight, flexibility, and processability. This review summarizes the research progress in triboelectric yarns. It starts with a systematic discussion of the working mechanism and manufacturing materials of triboelectric yarns. Subsequently, we discuss the four major methods of constructing triboelectric yarns including twisting/wrapping, coating, electrospinning, and other/composite methods. In particular, details about the energy harvesting performance, the triboelectric yarns' physical properties, and weaving/knitting capability are given. Finally, comments and perspectives are provided for the future design of high‐performance triboelectric yarns.
CeO2‐Supported Pt−Au Nanoparticles as Efficient Catalyst for CO Oxidation
Authors: Wang Haiyang , Gao Jianjing , Zhang Ruiyin , Ma Hao , Ma Cheng , Yao Ruijuan , Liang Miaomiao , Zhao Yuzhen , Miao Zongcheng 
Published: December 2022

AbstractThe nanorod shaped (Pt−Au)/CeO2 catalysts with varied Pt/Au ratio were achieved from Al91.7Ce8AuXPt0.15−X (X=0.05, 0.075, 0.1) precursor alloys through combined dealloying and calcination treatment. The surface morphology, microstructure as well as physicochemical features were characterized through XRD, SEM, TEM, XPS, Raman spectroscopy and N2 adsorption‐desorption tests. The catalytic measurement results imply that the (Pt0.075−Au0.075)/CeO2 catalyst displays optimal catalytic property with 50% and 99% reaction temperature as low as 37 °C, 80 °C, respectively. The (Pt0.075−Au0.075)/CeO2 was also stable after 60 h successive catalytic oxidation reaction. The outstanding catalytic performance is ascribed to the joint introduction of Pt and Au, which can suppress the agglomeration and growth of noble metal active phases during the catalytic process. What's more, the nanoscale interface formed between Pt&Au nanoparticles and CeO2 nanorods can also promote electron transfer rate, thus catalytic reaction efficiency is enhanced. The results will be of importance for design of novel nanoporous noble metal‐oxide‐based catalysts and application in exhaust treatment of fuel vehicles.
Myoglobin‐mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans
Authors: Christen Lisa , Broghammer Helen , Rapöhn Inka , Möhlis Kevin , Strehlau Christian , Ribas‐Latre Aleix , Gebhardt Claudia , Roth Lisa , Krause Kerstin , Landgraf Kathrin , Körner Antje , Rohde‐Zimmermann Kerstin , Hoffmann Anne , Klöting Nora , Ghosh Adhideb , Sun Wenfei , Dong Hua , Wolfrum Christian , Rassaf Tienush , Hendgen‐Cotta Ulrike B. , Stumvoll Michael , Blüher Matthias , Heiker John T. , Weiner Juliane 
Published: December 2022

AbstractBackgroundRecruitment and activation of brown adipose tissue (BAT) results in increased energy expenditure (EE) via thermogenesis and represents an intriguing therapeutic approach to combat obesity and treat associated diseases. Thermogenesis requires an increased and efficient supply of energy substrates and oxygen to the BAT. The hemoprotein myoglobin (MB) is primarily expressed in heart and skeletal muscle fibres, where it facilitates oxygen storage and flux to the mitochondria during exercise. In the last years, further contributions of MB have been assigned to the scavenging of reactive oxygen species (ROS), the regulation of cellular nitric oxide (NO) levels and also lipid binding. There is a substantial expression of MB in BAT, which is induced during brown adipocyte differentiation and BAT activation. This suggests MB as a previously unrecognized player in BAT contributing to thermogenesis.Methods and ResultsThis study analyzed the consequences of MB expression in BAT on mitochondrial function and thermogenesis in vitro and in vivo. Using MB overexpressing, knockdown or knockout adipocytes, we show that expression levels of MB control brown adipocyte mitochondrial respiratory capacity and acute response to adrenergic stimulation, signalling and lipolysis. Overexpression in white adipocytes also increases their metabolic activity. Mutation of lipid interacting residues in MB abolished these beneficial effects of MB. In vivo, whole‐body MB knockout resulted in impaired thermoregulation and cold‐ as well as drug‐induced BAT activation in mice. In humans, MB is differentially expressed in subcutaneous (SC) and visceral (VIS) adipose tissue (AT) depots, differentially regulated by the state of obesity and higher expressed in AT samples that exhibit higher thermogenic potential.ConclusionsThese data demonstrate for the first time a functional relevance of MBs lipid binding properties and establish MB as an important regulatory element of thermogenic capacity in brown and likely beige adipocytes.
A heterogeneous fault diagnosis approach to enhance performance of connected vehicles
Authors: Ranjan Senapati Biswa , Swain Sipra , Ranjan Swain Rakesh , Mohan Khilar Pabitra 
Published: December 2022

SummaryEvolution of wireless access technology, availability of smart sensors, and reduction in the size of the set up of the communication system have engrossed many researchers toward vehicular ad hoc network (VANET). Vehicle‐to‐vehicle and vehicle‐to‐access‐point communication in a vehicular environment facilitates the deployment of VANET for many different purposes. The success of any application implemented in a VANET relies on timely and accurate data dissemination across the nodes of the network. Implementation of any application is not going to be fruitful if the communication unit transmits incorrect sensor data due to the presence of a fault. This article focuses on the automatic detection of hard and soft faults for vehicular sensors and the classification of faults into permanent, intermittent, and transient faults using cloud‐based VANET. For the cloud service, ThingSpeak cloud is used. At the RSU of the VANET, hard fault detection is performed, and for this purpose, a time‐out strategy is proposed. The observation center, after receiving sensor status data over a vehicular cloud, does soft failure detection. The soft fault is identified by utilizing a comparative‐based technique during soft fault diagnosis. Soft faults are categorized using two machine learning algorithms: Support vector machine and logistic regression. The effectiveness of the suggested work is assessed using performance metrics like fault detection accuracy, false alarm rate, false positive rate, precision, accuracy, recall, and F1 score.
Auswirkungen des neuen Entwurfs zur EN 1996‐3 auf die Bemessung von Porenbeton‐Mauerwerk
Authors: Loderer Franz , Schoch Torsten 
Published: December 2022

AbstractIm Zuge der Entwicklung einer neuen Generation von Eurocodes werden auch die europäischen Mauerwerksnormen einer Evolution unterzogen. Dabei werden neue Entwürfe für alle vier Teile der EN 1996 erarbeitet – die finalen Entwurfsfassungen liegen mittlerweile vor. Für die Bemessung von Mauerwerkswänden in Deutschland sind insbesondere die in der DIN EN 1996‐3 geregelten vereinfachten Berechnungsmethoden für unbewehrte Mauerwerksbauten relevant. Bei Vergleichsberechnungen mit den aktuell in Deutschland bauaufsichtlich eingeführten Normen (DIN EN 1996‐3 in Verbindung mit DIN EN 1996‐3/NA) und dem vorliegenden Entwurf der europäischen Norm (prEN 1996‐3:2021) haben sich besonders für Mauerwerkswände mit Druckfestigkeiten von fk ≤ 2,0 N/mm2 und für Konstruktionen mit teilaufliegender Decke deutliche Unterschiede in den maximal möglichen Tragfähigkeiten gezeigt. Die Unterschiede in den Regelungen und die daraus resultierenden Abweichungen in den Bemessungsergebnissen werden in diesem Beitrag aufgezeigt und erläutert. Der inhaltliche Fokus des Dokuments liegt dabei auf Porenbeton‐Mauerwerk.
Implantation of sigmoid colon cancer into the endoscopic resection site of intramucosal rectal cancer: A case report
Authors: Nishino Kyohei , Hongo Masanori , Mori Naoko , Shimamoto Kazumi , Kobayashi Yu , Nakamura Fumiyasu , Hino Michiko , Togawa Takeshi , Andoh Akira , Ban Hiromitsu 
Published: December 2022

AbstractA 70‐year‐old woman was diagnosed with intramucosal rectal cancer and advanced sigmoid colon cancer at the same time. First, the intramucosal rectal cancer was curatively resected by endoscopic submucosal dissection, and surgery was subsequently performed for sigmoid colon cancer. After 20 months, a follow‐up colonoscopy revealed a tumor growth at the ulcer scar of the endoscopic submucosal dissection. Histological findings and KRAS mutation analysis suggested implantation of sigmoid colon cancer to the post‐endoscopic submucosal dissection site of intramucosal rectal cancer.
A survey on state of the inter body radio communication channel: Performance and solutions
Authors: Mezher Mohanad , Alabbas Amjed Razzaq , Ilyas Muhammad 
Published: December 2022

AbstractThe development of in‐vivo communications and networking systems has the potential for improving the healthcare delivery while also enabling the creation of new services and applications. In‐vivo communications provide wireless networked cyber‐physical systems of the embedded devices that enable accurate, quick, and cost‐effective responses under a variety of circumstances. Also, it is focused upon modeling and characterizing in‐vivo wireless channel, as well as contrasting it to other well‐known channels. In this paper, channel coding is also mentioned because it improves data rates and performance gain. This work also discusses present problems and potential research topics for in‐vivo communications. This article aims to show the researchers how the orthogonal frequency multiple access (OFDMA) technique improved the performance of in‐vivo channel and how it is outperformed compared to the other techniques (TDM, TDMA, CDMA and OFDM) also how the OFDMA outperformed equalizers and channel coding in terms of bit error rate with giving a significant improvement of data transmitting and avoiding inter symbol interference. However, when it comes to the in‐vivo communications, the modeling of in‐vivo wireless channel is vital. Understanding the features of the in‐vivo channel is critical for achieving optimal processing and designing successful procedures that allow WBANs to be arranged inside the human body.
Trends in the sample size, statistics, and contributions to the BrainMap database of activation likelihood estimation meta‐analyses: An empirical study of 10‐year data
Authors: Yeung Andy Wai Kan , Robertson Michaela , Uecker Angela , Fox Peter T. , Eickhoff Simon B. 
Published: December 2022

AbstractThe literature of neuroimaging meta‐analysis has been thriving for over a decade. A majority of them were coordinate‐based meta‐analyses, particularly the activation likelihood estimation (ALE) approach. A meta‐evaluation of these meta‐analyses was performed to qualitatively evaluate their design and reporting standards. The publications listed from the BrainMap website were screened. Six hundred and three ALE papers published during 2010–2019 were included and analysed. For reporting standards, most of the ALE papers reported their total number of Papers involved and mentioned the inclusion/exclusion criteria on Paper selection. However, most papers did not describe how data redundancy was avoided when multiple related Experiments were reported within one paper. The most prevalent repeated‐measures correction methods were voxel‐level FDR (54.4%) and cluster‐level FWE (33.8%), with the latter quickly replacing the former since 2016. For study characteristics, sample size in terms of number of Papers included per ALE paper and number of Experiments per analysis seemed to be stable over the decade. One‐fifth of the surveyed ALE papers failed to meet the recommendation of having >17 Experiments per analysis. For data sharing, most of them did not provide input and output data. In conclusion, the field has matured well in terms of rising dominance of cluster‐level FWE correction, and slightly improved reporting on elimination of data redundancy and providing input data. The provision of Data and Code availability statements and flow chart of literature screening process, as well as data submission to BrainMap, should be more encouraged.
The effect of health financing systems on health system outcomes: A cross‐country panel analysis
Authors: Gabani Jacopo , Mazumdar Sumit , Suhrcke Marc 
Published: December 2022

AbstractSeveral low‐ and middle‐income countries are considering health financing system reforms to accelerate progress toward universal health coverage (UHC). However, empirical evidence of the effect of health financing systems on health system outcomes is scarce, partly because it is difficult to quantitatively capture the ‘health financing system’. We assign country‐year observations to one of three health financing systems (i.e., predominantly out‐of‐pocket, social health insurance (SHI) or government‐financed), using clustering based on out‐of‐pocket, contributory SHI and non‐contributory government expenditure, as a percentage of total health expenditures. We then estimate the effect of these different systems on health system outcomes, using fixed effects regressions. We find that transitions from OOP‐dominant to government‐financed systems improved most outcomes more than did transitions to SHI systems. Transitions to government financing increases life expectancy (+1.3 years, p < 0.05) and reduces under‐5 mortality (−8.7%, p < 0.05) and catastrophic health expenditure incidence (−3.3 percentage points, p < 0.05). Results are robust to several sensitivity tests. It is more likely that increases in non‐contributory government financing rather than SHI financing improve health system outcomes. Notable reasons include SHI's higher implementation costs and more limited coverage. These results may raise a warning for policymakers considering SHI reforms to reach UHC.
Effective personal development plans contextualized: The role of the autonomy‐supportive people manager in sustaining employees' self‐directed learning
Authors: Lejeune Christophe , Beausaert Simon , Raemdonck Isabel 
Published: December 2022

AbstractThis qualitative research explores how the broader social context supports employees' self‐directed learning (SDL) when using a personal development plan (PDP), focusing especially on the people manager's role. Based on deductive and inductive analysis of verbatim transcripts from 28 semi‐structured interviews with employees and people managers in a non‐profit organization, the study reaches three main findings. First, it confirms the key role that people managers play within PDP practices and their need to balance autonomy support, and structure, adapting their leadership style to employees. Second, it confirms the added value of PDPs for long‐term learning goals and for creating a “humanitarian corridor” for personal and professional development, where efficient formal learning is complemented by informal learning activities embedded and situated in the work itself. Finally, it articulates a new conceptualization of SDL within a broader social context. These findings are complemented by practical implications and directions for future research.
Efficacy of generic sofosbuvir with daclatasvir compared to sofosbuvir/ledipasvir in genotype 4 hepatitis C virus: A prospective comparison with historical control
Authors: Joharji Hala , Alkortas Delal , Ajlan Aziza , Ahmed Mohamed , Al‐Ashgar Hamad , Al‐Quaiz Mohammed , Broering Dieter , Al‐Sebayel Mohammed , Elsiesy Hussien , Alkhail Faisal A. , Al‐Hamoudi Waleed K. , De Vol Edward , Amirah Almuhayshir Epi , Al‐Jedai Ahmed 
Published: December 2022

AbstractBackground and AimManagement of genotype 4 hepatitis C virus (HCV) has shifted to interferon‐free regimens with a high sustained virological response (SVR‐12), especially with NS5B/NS5A inhibitor combinations such as sofosbuvir and ledipasvir (Sof‐Led). The guidelines have recommended the combination of sofosbuvir and another NS5A inhibitor, daclatasvir, to manage HCV genotypes 1–3. However, its use was extended to genotype 4 HCV based on extrapolating evidence. Our aim is to assess the efficacy of generic sofosbuvir + branded daclatasvir (Sof‐Dac) compared to the Sof‐Led combination in treating genotype 4 HCV.MethodsThis study is an open‐label, 2‐period, noninferiority study that compared patients receiving a combination of generic sofosbuvir 400 mg and daclatasvir 60 mg orally daily (Group 2) prospectively to a historical control (Group 1) that included patients who received a combination of sofosbuvir/ledipasvir 400/90 mg orally daily. The primary endpoint is the proportion of patients who achieved SVR‐12.ResultsThe study included 111 patients in the (Sof‐Led) Group 1 and 109 patients (Sof‐Dac) Group 2. For the primary outcome, SVR‐12 was achieved in 106 (95.5%) of the patients in Group 1 versus 108 (99.1%) in Group 2 (p = 0.2). In addition, all patients who achieved SVR‐12 also achieved SVR‐24.ConclusionGeneric sofosbuvir combined with branded daclatasvir was safe and effective for treating genotype 4 HCV compared to Sof‐Led. This combination may significantly reduce the cost burden, enabling a larger pool of treated patients. Office of research affairs at KFSHRC RAC# 2171 036.
Factors controlling shallow subsurface dissolved reactive phosphorus concentration and loss kinetics from poorly drained saturated grassland soils
Authors: Smith Gen J. , McDowell Richard W. , Daly Karen , Ó hUallacháin Daire , Condron Leo M. , Fenton Owen 
Published: December 2022

AbstractShallow subsurface pathways dominate dissolved reactive phosphorus (DRP) losses in grassland soils that are: poorly drained, shallow, or have a perched water table in wetter months causing saturation‐excess runoff. Saturated conditions can lead to anoxia, which can accelerate phosphorus (P) loss. Two scales of investigation were utilized in this study. First, at the field scale, soil cores were extracted to 2.5 m, subdivided and samples extracted using water extractable P (WEP) and sodium‐bicarbonate‐dithionite extractable P (NaBD‐P). Second, at the laboratory scale, detailed incubation studies using field‐moist grassland topsoils from sites in Ireland and New Zealand examined the kinetics of WEP under anoxic (WEPanox) and oxic (WEPox) conditions with imposed temperature and soil P fertilizer input treatments. Results from soil‐core samples showed that redox‐sensitive NaBD‐P concentrations were depleted where artificial drainage lines were installed (100 cm deep), but WEP concentrations available to shallow flow were enriched in topsoil. The laboratory scale incubation experiment investigated the influence of temperature (3 vs. 18 °C), anoxia (designed to simulate saturation following a rainfall event), and superphosphate fertilizer (10 to 60 kg P ha−1 yr−1) on WEP concentrations over 24 h in three grassland topsoils (clay, silt, and sandy loam textures). Concentrations increased with fertilizer rate, temperature, and—in two soils—anoxic conditions. This was commensurate with nitrate (NO3−) depletion and the reductive dissolution of iron and manganese. The release of P during anoxia was complete within 24 h. The results highlighted late winter to spring as the riskiest period for topsoil P losses in shallow subsurface flow due to wet soil conditions, increasing temperatures, and low soil NO3− concentrations. This knowledge highlights the necessity to consider and refine tests used to assess topsoil P loss risk, where in the landscape P losses are likely, and what strategies can be used to mitigate losses.
Effect of surfactant compounding on the wettability of talcum powder
Authors: Meng Junqing , Chang Chenxi , Liang Yimin , Chen Haiyan 
Published: December 2022

AbstractTalcum powder is one of the leading causes of pneumoconiosis, adding compound surfactants to the dust removal process can significantly increase the effectiveness of the dust removal. Therefore, it is of great significance to study the effect of compound surfactants on the wettability of talcum powder. This paper focuses on the ability of compound surfactants to increase the wettability of talcum powder surface by using Materials Studio 8.0. The simulation results were analyzed from the water adsorbed amount, interaction energy, and water molecule concentration profile. Combined with the experimental data of contact angle, the optimal surfactant compounding method was obtained. The simulation results revealed that stable adsorption structures can be formed by the compound of anionic and nonionic surfactants, which can reduce the electrostatic repulsion between anionic surfactants effectively and promote the directional arrangement of nonionic surfactants on the talcum powder surface. When the molar ratio of sodium dodecyl sulfate (SDS) and Polysorbate 80 was 0.4:0.6, the amount of absorbed water reached 113, which is better than monomers and other compound surfactants. The contact angle experiment results indicated a consistent variation law with the simulation results. The contact angle decreased from 68.48° to 19.84° using the compounding method mentioned above, which has the optimum wetting effect among the four compounding methods. The research results will provide a reference for the application of compound surfactants in talcum powder dustproof work.