bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eye ball deviation patterns in traumatic cataract among children in Uttar Pradesh of India
Authors: Dave Sanjev , Manchanda J K , Manchanda Sameer , Manchanda Sheena , Rekha Chitra 
Published: October 2022

Paediatric cataract is an important cause of treatable childhood blindness, provided it is recognized and managed early. Timely diagnosis, management, and visual rehabilitation of a child with a paediatric cataract are crucial determinants of a favourable prognosis. This particular topic, study of pattern of deviation of eye ball after traumatic cataract in children was selected because of the difference between the firm literature of Keith Lyle and the clinical observations. This study includes analysis of 25 patients. The key findings of this study were: Maximum incidence of traumatic cataract was seen in 6-10 years of age group, that too more commonly in boys and it was 2.5 times more than that of girls. lncidence of perforating injuries leading to cataract was 1.5 times more common than blunt trauma. In paediatrics cataract, the Diminution of vision in cases of traumatic cataract is usually at the level of mature or hypermature cataract. 40% of cases showed deviation in the range of 11-20° (irrespective to divergence or convergence). There was higher incidence of Exotropia than esotropia. Originally eye was divergent as per evolution of binocular vision in primates & our study also came out with a conclusion that when there is no force or compulsion of binocular Vision, most of the eyes tended to be Divergent in children after traumatic cataract.
A comparative study of subtenon’s anaesthesia with peribulbar anaesthesia for manual small incision cataract surgery in patients with age related cataracts
Authors: Bhonsale Gayatri , Mehta Ishita , Gandhi Priyanka Hitesh , Ramakrishnan Reshma , Hussain Syed Faraaz 
Published: October 2022

To compare the safety, efficacy and ease of administration of subtenon’s anaesthesia with peribulbar anaesthesia in manual small incision cataract surgery(MSICS) and assess the surgeon and patient comfort.A prospective longitudinal study was conducted among 200 patients undergoing MSICS at a rural tertiary care hospital wherein patients were randomly divided into the two groups of peribulbar (P) and subtenon’s (ST) block.After randomization, 200 patients were assessed for various factors including pain at the time of administration of anaesthetic, time to attain akinesia, patient’s comfort and satisfaction score.200 eyes of 200 patients who underwent MSCIS were divided into Peribulbar and Subtenon’s group by random number table; of which 122 were women (61%) and 78 were men (39%). There was a significant difference in the amount of anaesthetic used, with the group P (8.37+1.19 ml) usage being more than the group ST(4.02+0.91 ml) (p&#60;0.001). Group P took significantly lesser time to attain akinesia compared to group ST. Group P achieved significantly higher degree of akinesia than group ST. (p&#60;0.001) Significantly greater number of eyes in the group ST required additional anaesthetic injection compared to the group P (p&#60;0.001). A significantly more number of patients experienced pain in the group P. (p=0.008)Significantly greater number of eyes in group ST had mild and moderate chemosis and subconjunctival haemorrhage compared to group P(p&#60;0.001).We found that subtenon’s anaesthesia was an equally effective technique for achieving analgesia and akinesia when compared to peribulbar anaesthesia in patients undergoing MSICS.
EQUIDAD EN LA EDUCACIÓN SUPERIOR TECNOLÓGICA: EL CASO DE LA UNIVERSIDAD TECNOLÓGICA DE TULA-TEPEJI, 2012-2016
Authors: Méndez Viera Sandra Patricia 
Published: October 2022

El trabajo incluye parte de los resultados de una investigación realizada en la Universidad Tecnológica de Tula-Tepeji (UTTT). La problemática que aborda refiere a que la política pública en materia de equidad educativa en México sólo ha sido evaluada a partir de indicadores generales que sólo miden el desempeño y los resultados en el acceso a educación superior, principalmente de grupos pertenecientes a los sectores más vulnerables de la sociedad, pero deja de lado el análisis de circunstancias y diferencias particulares que tienen los jóvenes estudiantes y que pueden ocasionar desigualdades a lo largo de su trayectoria educativa.
Por lo anterior, el estudio pretende examinar otras particularidades en las dimensiones de la equidad aplicadas a la educación superior, a fin de presentar resultados que contribuyan a valorar los alcances y retos de la política educativa que dio origen y desarrollo al SUT.
Se trata de una investigación explicativa y descriptiva que utilizó un enfoque mixto a través de un estudio de caso de corte transversal sobre el seguimiento de la trayectoria escolar de una generación de estudiantes que ingresó en septiembre 2012 y que egresó en enero del 2016.
El desarrollo del trabajo incluye un apartado de fundamentos teóricos, la descripción del problema, aspectos metodológicos que orientaron el proceso de la investigación y los resultados derivados del seguimiento de las trayectorias escolares (ingreso, permanencia y egreso) de la generación que se tomó como muestra y un apartado de discusión y conclusiones finales.
DETERMINANTS OF TRANSMISSION COVID-19 IN SOUTH SULAWESI
Authors: Masriadi Masriadi , Ulmy Mahmud Nur , Javid Nazli , Sarwin Muhammad , Lukman  , Hutami Megantari Sitti , Angraeni Suprianti Ayu 
Published: October 2022

Background: Corona Virus (COVID-19) is a new respiratory viral infectious disease that can cause illnesses ranging from the common cold to severe acute respiratory syndrome. Subsequently, as of May 31, 2022, the government of South Sulawesi reported 143,276 confirmed cases, 2,463 deaths, and 140,395 recovered patients. Purpose: To analyze the impact of behavior, travel history, and comorbidities on the incidence of COVID-19 in South Sulawesi. Methods: This is observational research with a cross-sectional study design and was conducted from January–April 2022 in 7 districts of South Sulawesi Province. A population of 650 respondents with a total sample of 161 patients confirmed positive and 189 suspected of having COVID-19. The Chi-square test and multiple logistic regression were used to analyze the data. Results: There was a relationship between travel history (p0.00; OR 2.19), knowledge (p0.03; OR 1.74), and actions (p0.00; OR 0.18) on the incidence of COVID-19. Additionally, no relationship was reported between comorbidities (p0.85), attitudes (p0.90), and level of knowledge (p0.08>(0.05) on the incidence of COVID-19. The most influential variable in the rapid spread was travel history, with an exp(B) value of 2.19 CI (95%) (LL=1.26; UL=3.80). Conclusion: The results showed that travel history, knowledge, and actions made a major contribution to the spread of COVID-19 in South Sulawesi Province.
MAPPING OF CHILDREN'S TUBERCULOSIS INCIDENCE BY COVERAGE OF BCG IMMUNIZATION, MALNUTRITION, AND HOME ENVIRONMENT
Authors: Brillianti Galih Haniin , Yovita Hendrati Lucia 
Published: October 2022

Background: Based on the Global Tuberculosis (TB) Report, Indonesia is one of the countries with a triple burden of TB, and TB disease can attack all age groups, including children. East Java Province in 2019 was ranked third in the highest number of pediatric TB cases in Indonesia. Purpose: This study aims to describe the distribution trend of tuberculosis cases in children in East Java Province in 2017-2018 based on BCG immunization coverage, cases of malnutrition, amount of healthy houses, and households with PHBS. Methods: The research design was a descriptive study with a correlation study design. The populations were all districts/cities in East Java Province, with as many as 38 districts. The data analysis technique to describe the trend distribution of tuberculosis in children was the health mapper software on a computer developed by World Health Organization (WHO). Results: The distribution of the incidence of tuberculosis in children in East Java from 2017 to 2018 tends to increase. The city of Surabaya became the area with the highest incidence of tuberculosis in children from 2017 to 2018. Based on a spatial map, most districts or cities with BCG immunization coverage, cases of malnutrition, several healthy homes, and high PHBS households experience tuberculosis incidence in children is high. Conclusion: Based on the map, spatially, districts or cities with high cases of tuberculosis in children mainly occur in areas with cases of malnutrition, the number of healthy home environments, and high coverage of BCG immunization as well.
The Role of Teacher's Pedagogic Competence in Cultivating Character Based on Scientific Learning in Elementary Schools
Authors: Mukhlisah Siti , Nurdyansyah Nurdyansyah 
Published: October 2022

The role of teacher pedagogical competence in character building is the teacher's ability to design and implement learning that educates and is adapted to existing character values, and can direct the potential of students and evaluate learning. The purpose of this study 1). Analyzing the role of teacher pedagogical competence in character building based on scientific learning at SD Muhammadiyah 2 Tulangan, 2) Analyzing what factors support and hinder the cultivation of scientific-based character. This study uses qualitative research with descriptive methods. The research subjects were class III homeroom teachers, principals of SD Muhammadiyah 2 Tulangan and administrative staff. Data collection techniques using 1) Observation 2) Interview 3) Documentation. While the data analysis technique used the data triangulation technique. ,and has been made with a variety of techniques and methods that are interesting and fun. 2) Factors that influence character building in SD Muhammadiyah Tulangan are internal and external factors, namely the collaboration between teachers and parents.
Highlights:

Teacher pedagogical competence plays a crucial role in character building through adaptable and value-based learning.
Factors influencing character building include internal and external elements, with collaboration between teachers and parents being vital.
This study utilizes qualitative research with descriptive methods, employing observation, interviews, and documentation for data collection and triangulation.

Keywords: Teacher pedagogical competence, Character building, Scientific learning, Qualitative research, Data triangulation
Impact of Beyond Fistula Programming on Economic, Psychosocial and Empowerment Outcomes Following Female Genital Fistula Repair: A Retrospective Study
Authors: Ayadi Alison El , Alway Jessica , Matityahu Debra , Kichwen Celine , Wilson Susan , Mabeya Hillary 
Published: October 2022

Abstract
Background
The severe physical, psychosocial, and economic consequences of fistula suggest that post-surgical reintegration programming that incorporates a holistic approach may optimize recovery. However, there is a gap in knowledge around best practices for women’s post-surgical reintegration programming and limited assessment of reintegration programming among women who have undergone genital fistula repair. Thus, the objective of this study was to retrospectively assess changes in economic status, psychosocial status and empowerment among women who participated in Beyond Fistula reintegration programming following surgical fistula repair.
Methods
We conducted a retrospective survey among 100 Beyond Fistula (El Doret, Kenya) participants capturing sociodemographic characteristics, obstetric and fistula history, program participation, economic status (income and employment), psychosocial status (reintegration, self-esteem, depressive symptoms), and empowerment (engagement in household decision-making and intimate partner violence). Economic status, psychosocial status and empowerment were captured for two time points: prior to program participation and currently and compared using paired t-tests or McNemar’s tests.
Results
Specifically, when comparing economic status prior to program participation to afterwards, we noted statistically significant increases in the proportion of individuals owning property (28.0% vs. 38.0%, p=0.0063), having current source of income (19.0% vs. 56.0%, p<0.001), and saving or investing income (11.0% vs. 37.0%, p<0.001). We also identified statistically significant increases from pre to post programming in self-esteem (5.0 (IQR 4.0-5.0) vs. 5.0 (IQR 5.0-5.0), p=0.0001), reintegration (53.0 (IQR 43.0-69.0) vs. 65.0 (IQR 51.0-72.0), p<0.001) and level of input into household economic decision-making (2.0 (SD 1.0) vs. 2.3 (SD 1.0), p=0.004).
Conclusions
Our findings suggest that participation in Beyond Fistula programming improved economic status, psychosocial status, and empowerment of participants. Post-surgical interventions incorporating a holistic approach can advance recovery through supporting psychosocial and economic wellbeing and should be offered to women undergoing genital fistula repair.
Global warming accelerates soil heterotrophic respiration
Authors: Nissan Alon , Alcolombri Uria , Peleg Nadav , Galili Nir , Jimenez-Martinez Joaquin , Molnar Peter , Holzner Markus 
Published: October 2022

Abstract
Carbon efflux from soils is the largest terrestrial carbon source to the atmosphere, yet it remains one of the most uncertain fluxes in the Earth’s carbon budget. A dominant component of this flux is heterotrophic respiration, influenced by several environmental factors, most notably soil temperature and moisture. We developed a mechanistic model from micro to global scale to explore how changes in soil water content and temperature affect soil heterotrophic respiration. Simulations, laboratory measurements, and field observations validate the new approach. Estimates from the model show that heterotrophic respiration has been increasing since the 1980s at a rate of about 1.7% per decade globally. Using future projections of surface temperature and soil moisture, the model predicts a global increase of about 40% in heterotrophic respiration by the end of the century under the worst-case emission scenario, which is driven principally by the reduction of soil moisture rather than temperature increase.
WITHDRAWN: Effects of Nitrogen and Zinc Fertilization on Alleviating Cadmium Accumulation in Durum Wheat Grains
Authors: TOSUN Yener Kortan , Erdem Halil , GENCE Cabir Çağrı 
Published: October 2022

Abstract
The health of the people, which frequently consume bakery items in their diets, is threatened by the production of cereals in cadmium (Cd) contaminated soils. Durum wheat (Triticum durum L.) is extensively cultivated in the world and of special concern due to its higher Cd accumulation potential than other cereals. This study sought to determine how zinc (Zn) and nitrogen (N) applications affected the grain Cd concentration of durum wheat cultivated in a soil contaminated with Cd. The experiment was set up with randomized plots and four replications. The conditions used to develop the durum wheat included low (0.05 mg Zn kg− 1) and sufficient (5 mg Zn kg− 1) Zn, as well as inadequate (200 mg kg− 1) and optimal (400 mg N kg− 1) and high (600 mg N kg− 1) N levels. Application rates for Cd were 0 and 5 mg Cd kg− 1. The findings demonstrated that 5 mg kg− 1 application resulted in a statistically significant (p < 0.01) rise in grain Cd contents of durum wheat in low and sufficient Zn and all N regimens, although straw and grain yields considerably decreased (p < 0.01). However, increasing N applications with sufficient soil Zn concentration caused an increase in the straw and grain yield of durum wheat and a significant decrease in grain Cd concentrations. The grain Cd concentration in low Zn and optimum N treatment under Cd application was 6206 µg kg− 1, while the grain Cd concentration decreased by 26.3% in the Zn and optimum N treatment to 4574 µg kg− 1. In addition, Cd application caused a decrease in the grain Zn concentrations of durum wheat under low Zn conditions, whereas Zn concentration of wheat grain increased in sufficient soil Zn concentration under Cd application to soil. The results revealed that N applications alone are not sufficient to prevent Cd accumulation in wheat grain, therefore Zn fertilization is needed, especially in Zn deficient soils to lower the Cd concentration of wheat grain in addition to N application.
Targeting PIEZO1 refines macrophage function in atherosclerosis
Authors: Pourteymour Shirin , Fan Jingxue , Majhi Rakesh Kumar , Guo Shuyuan , Huang Zhen , Liu Ying , Sun Xin , Winter Hanna , Bäcklund Alexadra , Skenteris Nikolaos Taxiarchis , Chernogubova Ekaterina , Werngren Olivera , Skogsberg Josefin , Li Yuhuang , Matic Ljubica , Hedin Ulf , Maegdefessel Lars , Ehrenborg Ewa , Tian Yen , Jin Hong 
Published: October 2022

Abstract
The increasing prevalence of global atherosclerosis and its complications demand efforts to discover novel targets for therapeutic interventions. In the present study, we identified increased expression of the mechanosensitive calcium channel Piezo 1 transcripts in mouse and human atherosclerosis, driven by infiltration of PIEZO1-expressing macrophages. We pharmacologically activated or inhibited PIEZO1 both in vitro and in vivo to investigate its role in atherosclerosis. In vitro administration of Yoda1, a PIEZO1 specific agonist, increased foam cell apoptosis and enhanced phagocytosis by macrophages. Mechanistically, we found intracellular F-actin rearrangement, elevated mitochondrial ROS levels and induction of mitochondrial fragmentation upon PIEZO1 activation, as well as increased expression of anti-inflammatory genes. In vivo, Yoda1 treated ApoE−/− mice showed regression of atherosclerosis, enhanced plaque stability in advanced lesions, reduced plaque size and necrotic core, increased collagen content, coupled with reduced expression levels of inflammatory markers. Our data suggest that the Ca2+-permeable channel PIEZO1 is a novel and promising therapeutic target to enhance macrophage functions towards atherosclerosis treatment.
Response to budesonide formoterol and omalizumab combination therapy: a retrospective study in adults with allergic asthma
Authors: Li Na , Cao Lingfeng , Zhang Ming , Fei Chunyuan , Deng Jingjing 
Published: October 2022

Abstract
Background
Omalizumab is an anti-IgE humanised monoclonal antibody marketed in China for the conventional treatment of poorly controlled moderate to severe allergic asthma. Numerous clinical trials have demonstrated the effectiveness of omalizumab, but data from studies in actual clinical treatment are still relatively limited.
Methods
Data were collected on 32 patients who met the inclusion criteria. Clinical characteristics before and after omalizumab treatment were collected to analyze the relationship between changes in serum total IgE levels and peripheral blood EOS levels, FEV1, PEF, OCS dosage, ATC score and number of acute exacerbations and treatment response, to observe the efficacy of omalizumab treatment and to investigate whether baseline clinical characteristics such as serum total IgE and EOS levels could predict treatment response.
Results
Using the ACT score as an evaluation, 68.75% of patients benefited from omalizumab treatment at the end of 16 weeks. Response group has a reduction in OCS dosage (P values 0.026, 0.039), a significant reduction in ACT scores (both P < 0.001) and a reduction in the number of acute exacerbations (P 0.034, 0.025 respectively) after omalizumab treatment. The Binary logistics analysis of factors affecting the effectiveness of omalizumab in the treatment of allergic asthma were total serum IgE and the presence of comorbidities (p-values of 0.039 and 0.046 respectively).
Conclusions
Omalizumab combined with budesonide formoterol was effective after 16 weeks of treatment. Serum IgE levels and the presence of comorbidities predicted response to omalizumab treatment.
Mitigation of Aflatoxin metabolites in food and feed using phenolic compounds identified by insilico study
Authors: Sajid Muhammad Wasim , Sarfraz Ayesha 
Published: October 2022

Abstract
Milk is considered a complete diet that contains nutrients in balance. Apart from different possible concerns, mycotoxins are considered a serious cancer-causing compound from which many are considered extremely toxic. With the industrialization and rapid increase in population, there is a serious concern to be managed with respect to food safety. The permissible limit (0.05µg/l) defined by the EU is being followed in Pakistan. The purposed study was to screen out AFM1 contamination in goat milk and In-silico identification of possible ways to interrupt the pathway of AFM1. The maximum concentration of AFM1 0.0669 µg/l exceeds the permissible limit and minimum 0.0015µg/l below the permissible limit was observed in some Goat milk sample collected in surroundings of Sahiwal Pakistan. 10% milk samples were reported highly contaminated with AFM1 as exceeds permissible limit value. For pathway intruption, an enzyme (O- methylsterigmatocystin oxidoreductase) was identified directly involved in AFB1 synthesis and further conversion. The molecular docking was performed against this enzyme to inhibit the conversion into toxic compound. Essential oil was used to inhibit fungal growth and detoxification of toxic substances. The ligand compounds were extracts of naturally occurring plants such as walnut, black currants, blueberries, raspberries, red currants, cranberries and Adhatoda vasica (Nees). Docking of compounds was performed by AutoDock Vina and after and interaction visualization. A Lead ZINC000030729894 was identified with good docking results and interaction.
Primary squamous cell carcinoma of the duodenum: a case report and literature review
Authors: Yi-fan Hui , Xia Zheng , Wei Lu 
Published: October 2022

Abstract
Duodenal squamous cell carcinoma is extremely uncommon among gastrointestinal malignancies. The diagnosis and treatment were less understood. We report a case of duodenal squamous cell carcinoma with liver and adrenal metastasis, who was treated with gemcitabine and S-1 and obtained a PFS of 8 months eventually. Additionally, the features and treatment of primary duodenal carcinoma reported so far were reviewed in this paper. Obviously, further case reports such as ours can generate deeper cognition, which is essential for the nature of this entity and establish management guidelines.