bluuebunny/crossref_metadata_2025_split huggingface dataset:
First morphological and phylogenetic data on Ligophorus kaohsianghsieni (Platyhelminthes: Monogenea) from the Black Sea and the Sea of Japan and molecular evidence of deep divergence of sympatric Ligophorus species parasitizing Planiliza haematocheilus
Authors: Vodiasova E. , Atopkin D. , Plaksina M. , Chelebieva E. , Dmitrieva E. 
Published: November 2022

Abstract
Ligophorus kaohsianghsieni (Gusev, 1962) Gusev, 1985 was collected from the so-iuy mullet Planiliza haematocheilus (Temminck & Schlegel, 1845) from the Black Sea and the Sea of Japan. DNA sequences data for L. kaohsianghsieni, as well as its morphological characters from the Sea of Japan were obtained for the first time. Significant morphometric and genetic diversity between specimens of L. kaohsianghsieni from the Black-Azov Sea region and the Sea of Japan were not found. For the first time, the molecular phylogeny of L. kaohsianghsieni based on three fragments of the nuclear DNA ribosomal cluster (18S, internal transcribed spacer 1 and 28S) was reconstructed. Molecular analysis of Ligophorus species from the Atlantic and Pacific Oceans revealed a significant phylogenetic distance between L. kaohsianghsieni and two others species (Ligophorus pilengas and Ligophorus llewellyni) from the same host (P. haematocheilus) and region. This result indicates the lack of correspondence between the phylogenetic and geographical closeness of the hosts and the relation of their parasites from the genus Ligophorus.
In vitroliquid culture of the mollusc-parasitic nematodePhasmarhabditis(Rhabditida: Rhabditidae)
Authors: Pieterse A. , Haukeland S. , Půža V. , Ross J. L. , Malan A. P. 
Published: November 2022

AbstractThe success of the mollusc-parasitic nematode,Phasmarhabditis hermaphrodita(Schneider) Andrássy (Rhabditida: Rhabditidae), as a biological control agent in Europe has led to worldwide interest in phasmarhabditids as biocontrol agents. In this study, the mass culture potential of three phasmarhabditids, namelyPhasmarhabditis papillosa,Phasmarhabditis kenyaensisandPhasmarhabditis bohemica, was assessed. In addition, ten bacterial candidates, consisting of seven associated with slugs and three associated with entomopathogenic nematodes, were investigated. The bacteria were tested for their ability to cause mortality toDeroceras invadens, as well as to support nematode growth. Initial mortality studies demonstrated thatKluyvera,AeromonasandPseudomonasspp. (AP3) caused 100% mortality when they were injected into the haemocoel ofD. invadens. However, in growth studies,Pseudomonassp. (AP4) was found to be the most successful bacterium, leading to recovery and reproduction in almost all nematode species, except forP. kenyaensis. In flask studies,P. bohemica, which showed exceptional growth withPseudomonassp. (AP1), was chosen for further investigation. The effect of inoculating flasks with different concentrations ofPseudomonassp. (AP1), as well as with different concentrations ofP. bohemica, was evaluated by assessing the nematode populations for 14 days. The results indicated that the lowest, 1% (v/v), bacteria inoculation led to higher total nematode and to infective juvenile (IJ) yield, with flasks with the highest IJ inoculum (3000 IJs/ml) having a positive effect on the total number of nematodes and IJs in cultures ofP. bohemica. This study presents improvements for the mass-culturing of nematodes associated with molluscs.
On the presence of the deep-water mytilid Gigantidas horikoshii (Bivalvia: Mytilidae) in Taiwanese waters
Authors: Mellado Claudio , Zambrano Nicolás , Aliaga Juan Antonio , Ballesteros Luis , Araya Juan Francisco 
Published: November 2022

AbstractWe present the first record of the very large deep-sea mytilid Gigantidas horikoshii Hashimoto & Yamane, 2005 outside of its type distribution, based on a juvenile specimen collected by fishermen at the Tashi fishing grounds east of Taiwan. This record extends the distribution of the species in about 20 latitudinal degrees to the west (about 1916 km), and it is the first record for this species outside the Izu-Ogasawara Island-arc, southern Japan, representing the westernmost geographic limit of this species and the first record in Taiwanese waters.
Religion, political parties, and Thailand’s 2019 election: Cosmopolitan royalism and its rivals
Authors: Larsson Tomas 
Published: November 2022

AbstractThe political salience of religious issues and identities has been rising in Thailand, and this is increasingly reflected in electoral politics. Thai political parties seek to position themselves in relation to struggles over the location of the ideological centre of gravity, which has pitted defenders of the religio-political status quo—a monarchy-centred civil-religious nationalism—against Buddhist nationalists, on the one hand, and proponents of greater secularization, on the other. In the 2019 general election, political entrepreneurs ‘particized’ these religio-political differences, which has far-reaching implications for majority-minority relations, to an extent that appears unprecedented in recent Thai political history. This argument is developed through an analysis of the platforms, policies, and rhetoric put forward by political parties contesting the election, which concluded an almost five-year period of direct military rule. This analysis suggests we need to pay greater attention to the role of political parties and electoral competition in maintaining and contesting the secular settlement in Thailand.
Predicting adolescent depression and anxiety from multi-wave longitudinal data using machine learning
Authors: Hawes Mariah T. , Schwartz H. Andrew , Son Youngseo , Klein Daniel N. 
Published: November 2022

AbstractBackgroundThis study leveraged machine learning to evaluate the contribution of information from multiple developmental stages to prospective prediction of depression and anxiety in mid-adolescence.MethodsA community sample (N = 374; 53.5% male) of children and their families completed tri-annual assessments across ages 3–15. The feature set included several important risk factors spanning psychopathology, temperament/personality, family environment, life stress, interpersonal relationships, neurocognitive, hormonal, and neural functioning, and parental psychopathology and personality. We used canonical correlation analysis (CCA) to reduce the large feature set to a lower dimensional space while preserving the longitudinal structure of the data. Ablation analysis was conducted to evaluate the relative contributions to prediction of information gathered at different developmental periods and relative to previous disorder status (i.e. age 12 depression or anxiety) and demographics (sex, race, ethnicity).ResultsCCA components from individual waves predicted age 15 disorder status better than chance across ages 3, 6, 9, and 12 for anxiety and 9 and 12 for depression. Only the components from age 12 for depression, and ages 9 and 12 for anxiety, improved prediction over prior disorder status and demographics.ConclusionsThese findings suggest that screening for risk of adolescent depression can be successful as early as age 9, while screening for risk of adolescent anxiety can be successful as early as age 3. Assessing additional risk factors at age 12 for depression, and going back to age 9 for anxiety, can improve screening for risk at age 15 beyond knowing standard demographics and disorder history.
Epidemiological evaluation of mass testing in a small municipality in the Netherlands during the SARS-CoV-2 epidemic
Authors: Heijmink Lisanne , Tönis Juul , Gilhuis Niek , Gerkema Maartje , Hart Lotte , Raven Stijn , van den Boogaard Jossy , Hofhuis Agnetha , van den Hof Susan , Visser Olga 
Published: November 2022

Abstract
During 6 weeks in February–March 2021, the Dutch municipal health service Utrecht studied the epidemiological effects on test incidence and the detection of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mass testing (MT). During MT, inhabitants of Bunschoten could repeatedly test regardless of symptoms and as often as desired at the close-by test facilities in the municipality. Data from the regular COVID-19 registration was used for analysis. In Bunschoten, MT caused a significant increase in test incidence and an immediate increase in the number of detected active infections, in contrast to a stabilisation in the rest of the province of Utrecht. Age distribution of test incidence shifted to the older population in Bunschoten during MT. During MT, there was a 6.8 percentage point increase in detected asymptomatic cases, a 0.4 percentage point increase in pre-symptomatic cases and a decrease of 0.5 days between onset of symptoms and test date. This study has shown that MT increases test incidence and helps to obtain a more complete view of the presence of SARS-CoV-2 in a community, which can be useful in specific situations with a defined target group or goal. However, the question remains open whether the use of MT is proportionate to the overall gain.
Biased adult sex ratios in Western Europe populations of Little BustardTetrax tetraxas a potential warning signal of unbalanced mortalities
Authors: Serrano-Davies Eva , Traba Juan , Arroyo Beatriz , Mougeot François , Cuscó Francesc , Mañosa Santi , Bota Gerard , Faria Nuno , Villers Alexandre , Casas Fabián , Attie Carole , Devoucoux Pierrick , Bretagnolle Vincent , Morales Manuel B. 
Published: November 2022

SummaryAdult sex ratios (ASRs) have proved to correlate with population trends, which make them potential useful indicators of a species’ population trajectory and conservation status. We analysed ASRs and proportion of juveniles in flocks of an endangered steppe bird, the Little BustardTetrax tetrax, using surveys made during the non-breeding period in seven areas within its Western European range (one in Portugal, four in Spain, and two in France). We found overall male-biased ASRs, as all the seven surveyed areas showed a male-biased ASR mean value. Five areas were below the threshold median value (female sex ratio = 0.4) considered to be consistent with an increased probability of extinction, according to earlier population viability analyses for the species. We also found a significant positive correlation between female ratio and the proportion of young individuals in the non-breeding flocks surveyed. Our results (strongly male-biased ASRs) support the hypothesis that the viability of Little Bustard populations in Western Europe is threatened by an excess of female mortality, something that should be quantified in the future, and emphasise the value of monitoring sex ratio as a population viability indicator in species where monitoring survival is difficult to achieve.
The impact of particular safety behaviours on perceived likeability and authenticity during interpersonal interactions in social anxiety disorder
Authors: Dabas Grishma , Rowa Karen , Milosevic Irena , Moscovitch David A. , McCabe Randi E. 
Published: November 2022

AbstractBackground:Safety behaviours are hypothesized to play a vital role in maintaining social anxiety disorder (SAD), in part by orienting socially anxious individuals to adopt an avoidance-based mindset focused on self-protection and self-concealment. Evidence suggests an association between safety behaviour use and negative social outcomes for individuals with SAD. However, research has largely focused on the broad group of safety behaviours, whereas specific subtypes have received less attention.Aim:The present study aimed to further our understanding of the negative interpersonal consequences of specific types of safety behaviours for individuals with SAD by examining whether active, inhibiting/restricting, or physical symptom management safety behaviour use affects perceived likeability and authenticity during a conversation with a stranger.Method:Individuals with SAD (n = 29; mean age 35.5 years) and healthy control (non-SAD) participants (n = 40; mean age 18.6 years) engaged in a semi-structured social interaction with trained confederates.Results:Participants with SAD were perceived as significantly less likeable and authentic by the confederates, and rated themselves as significantly less authentic compared with those without SAD. The association between group status and likeability was mediated by the use of inhibiting/restricting safety behaviours and the association between group status and participant-rated authenticity was mediated by the use of both inhibiting/restricting and active safety behaviours, but not physical symptom management strategies.Conclusions:These results contribute to a growing literature suggesting that some, but not all, safety behaviours may play an important role in creating the negative social outcomes that individuals with SAD experience.
Unifying Framework for Optimizations in Non-Boolean Formalisms
Authors: LIERLER YULIYA 
Published: November 2022

AbstractSearch-optimization problems are plentiful in scientific and engineering domains. Artificial intelligence (AI) has long contributed to the development of search algorithms and declarative programming languages geared toward solving and modeling search-optimization problems. Automated reasoning and knowledge representation are the subfields of AI that are particularly vested in these developments. Many popular automated reasoning paradigms provide users with languages supporting optimization statements. Recall integer linear programming, MaxSAT, optimization satisfiability modulo theory, (constraint) answer set programming. These paradigms vary significantly in their languages in ways they express quality conditions on computed solutions. Here we propose a unifying framework of so-called extended weight systems that eliminates syntactic distinctions between paradigms. They allow us to see essential similarities and differences between optimization statements provided by distinct automated reasoning languages. We also study formal properties of the proposed systems that immediately translate into formal properties of paradigms that can be captured within our framework.
Trapezoidal pulse-switching strategy for failure correction of multi-pattern time-modulated linear array
Authors: Mukherjee Ananya , Mandal Sujoy , Mandal Sujit K. , Ghatak Rowdra 
Published: November 2022

AbstractIn this paper, a novel approach for simultaneously correcting multiple degraded patterns under the failure condition of time-modulated linear arrays is proposed. The approach is based on the use of trapezoidal pulse with non-zero rise/fall time to control the switching status of the radio frequency switches that enables ON-OFF keying modulation of the array elements. After deriving a closed form expression of harmonic power loss and through the in-depth analysis, it is explored that the proposed trapezoidal pulse, because of having non-zero rise/fall time, provides less undesired harmonic power loss as compared to the conventionally used rectangular pulse with ideally zero rise/fall time. With the aim of reconstructing the degraded patterns with improved directivity and suppressed higher sideband power, three pulse-switching strategies based on rectangular and trapezoidal pulse have been employed, and their comparative performances prove the superiority of the proposed approach.
Characteristics of a Jumping Cirrus Retrieved From Rapid Scans by Himawari‐8
Authors: Iwasaki S. , Yamaguchi T. 
Published: November 2022

AbstractA jumping cirrus (JC) is a cloud that forms a few kilometers above an anvil cloud downwind of an overshooting top (OT). A JC transports water vapor from the troposphere into the stratosphere, where water vapor is an important greenhouse gas. However, the microphysics of JC has not been explored thus far. Herein, 2.5‐min rapid scan images obtained from the geostationary weather satellite Himawari‐8 were analyzed for JC observations. A dark plume was observed to appear suddenly above an anvil cloud downwind of OTs and moved 1 km upwind within 2.5 min. The brightness temperature of the plume showed that it overlaid the anvil cloud. These characteristics matched those of a JC. The reflectivity of the assumed JC at a wavelength of 0.64 μm was 0.62, whereas that of the anvil cloud on the sunny side of the JC was 1.02. The measured reflectivities were compared to those simulated using ray tracing to retrieve the microphysics of the JC. The results indicated that dark reflectivity occurred because the JC was isolated above the anvil cloud, and bright reflectivity occurred because the anvil was illuminated by the sun and scattered light from the JC. The retrieved effective radius and ice water content of the JC were 23.4–28.0 μm and 0.12–0.15 g m−3, respectively. The JC appeared to transport 10 × 103 t of ice water above deep convection within 10 min. We applied the results to analyzing the best satellite geometry for detecting and measuring JC.
Hydro Economic Asymmetries and Common‐Pool Overdraft in Transboundary Aquifers
Authors: Mullen Connor , Müller Marc F. , Penny Gopal , Hung Fengwei , Bolster Diogo 
Published: November 2022

AbstractThe common‐pool nature of groundwater resources creates incentives to over pump that contribute to their rapid global depletion. In transboundary aquifers, users are separated by a territorial border and might face substantially different economic and hydrogeologic conditions that can alternatively dampen or amplify incentives to over pump. We develop a theoretical model that couples principles of game theory and groundwater flow to capture the combined effect of well locations and user asymmetries on pumping incentives. We find that heterogeneities across users (here referred to as asymmetries) in terms of either energy cost, groundwater profitability or aquifer response tend to dampen incentives to over pump. However, combinations of two or more types of asymmetry can substantially amplify common‐pool overdraft, particularly when the same user simultaneously faces comparatively higher costs (or aquifer response) and profitability. We use this theoretical insight to interpret the emergence of the Disi agreement between Saudi Arabia and Jordan in association with the Disi‐Amman water pipeline. By using bounded non‐dimensional parameters to encode user asymmetries and groundwater connectivity, the theory provides a tractable generalized framework to understand the premature depletion of shared aquifers, whether transboundary or not.
The mitochondrial unfolded protein response (UPRmt) protects against osteoarthritis
Authors: Zhou Zhibin , Lu Jiajia , Yang Mei , Cai Jiao , Fu Qiang , Ma Jun , Zhu Lei 
Published: November 2022

AbstractThe mitochondrial unfolded protein response (UPRmt) is a mitochondrial-to-nuclear signaling pathway that is activated to maintain mitochondrial function when there is an accumulation of misfolded proteins within mitochondria. Mitochondrial function is essential for chondrocyte homeostasis, and mitochondrial dysfunction is a characteristic of osteoarthritis (OA). However, the role of the UPRmt in OA remains unclear. In the present study, the level of the UPRmt was examined in primary mouse chondrocytes subjected to different stresses and in the articular cartilage of OA model mice and OA patients. The relationship between UPRmt activation and OA progression was studied. The UPRmt was induced in primary mouse chondrocytes subjected to diverse stresses and in the cartilage of OA mice. Enhancement of the UPRmt with nicotinamide riboside (NR) significantly improved mitochondrial function, reduced chondrocyte death, attenuated OA pain, and ameliorated OA progression, and the protective effects decreased significantly in chondrocyte-specific Atf5 knockout (ATF5f/fCol2a1-CreERT2) mice. UPRmt induction was also identified in the articular cartilage of OA patients and was associated with reduced chondrocyte death, less severe hip pain, and lower levels of inflammation in synovial fluid. These findings identify the induction of the UPRmt in primary mouse chondrocytes exposed to pathological stresses and in the articular cartilage of OA model mice and OA patients. Enhancement of the UPRmt ameliorates OA progression, suggesting that the UPRmt exerts a protective effect against OA and may be a potential diagnostic and therapeutic strategy for OA.
Metformin can mitigate skeletal dysplasia caused by Pck2 deficiency
Authors: Li Zheng , Yue Muxin , Heng Boon Chin , Liu Yunsong , Zhang Ping , Zhou Yongsheng 
Published: November 2022

AbstractAs an important enzyme for gluconeogenesis, mitochondrial phosphoenolpyruvate carboxykinase (PCK2) has further complex functions beyond regulation of glucose metabolism. Here, we report that conditional knockout of Pck2 in osteoblasts results in a pathological phenotype manifested as craniofacial malformation, long bone loss, and marrow adipocyte accumulation. Ablation of Pck2 alters the metabolic pathways of developing bone, particularly fatty acid metabolism. However, metformin treatment can mitigate skeletal dysplasia of embryonic and postnatal heterozygous knockout mice, at least partly via the AMPK signaling pathway. Collectively, these data illustrate that PCK2 is pivotal for bone development and metabolic homeostasis, and suggest that regulation of metformin-mediated signaling could provide a novel and practical strategy for treating metabolic skeletal dysfunction.
Evaluating complete remission with partial hematologic recovery (CRh) as a response criterion in myelodysplastic syndromes (MDS)
Authors: Brunner Andrew M. , Gavralidis Alexander , Ali Najla Al , Hunter Anthony , Komrokji Rami , Zeidan Amer , Sallman David A. 
Published: November 2022

AbstractMyelodysplastic syndromes (MDS) treated with DNMTI therapy have responses according to the 2006 IWG response criteria. CR responses have had the strongest association with OS. Recently, CR with partial hematologic recovery (CRh; i.e. blasts <5%, ANC > 500, platelets > 50) has been evaluated in AML, but its relevance is unknown in MDS. We identified adult patients with MDS treated with DNMTIs. We assessed best overall response to therapy according to IWG 2006 criteria, and subsequently identified patients meeting CRh criteria from the subgroup with SD or mCR. We evaluated duration of therapy and overall survival according to response. We identified 311 patients with MDS who received treatment between 2007 and 2018. The median age at the time of therapy was 69 years (range 23–91). Median follow up was 60 months. According to IWG 2006, responses included CR (n = 43, 14%), PR (n = 2, 1%), mCR (n = 57, 18%), SD (n = 149, 48%) and PD (n = 60, 19%). 79 patients (25%) achieved HI. A total of 62 patients (20%) met CRh criteria leading to reclassification of mCR (now n = 26, 8%) or SD (now n = 118, 38%). Patients achieving CR had similar time on therapy (median 8.1mo) compared to CRh (median 6mo, HR 1.4, 95% CI 0.9–2.0), and longer than other responses (p < 0.001). OS varied according to response; median OS was similar between CR (23.3mo) and CRh (25mo, HR 1.28 [0.79–2.08]), which was longer than those with mCR (17.2mo, HR 1.71 [0.96–3.05]), SD (16.3mo, HR 1.61 [1.04–2.48]), and PD (8.7mo, HR 3.04 [1.91–4.83]) (p < 0.001). OS associations with CR/CRh were confirmed in multivariable analysis accounting for allogeneic transplant. MDS patients who achieve a CRh response had similar survival and duration on therapy as patients who achieve CR response and superior to other IWG responses. These data support further evaluation of CRh into future response criteria and clinical trials.