bluuebunny/crossref_metadata_2025_split huggingface dataset:
C60. Management of Symptomatic Wolff-Parkinson-White (WPW) Syndrome: A Case Report
Authors: Lestari Puspa , Rizal Ardian , A Yudi Putra , Fadlan M R , Ardhi R A Lukitasari Ayu Galuh 
Published: April 2022

Abstract

Background
Atrioventricular reentrant tachycardia (AVRT) could be the reentrant tachyarrhythmia that occurs in Wolff-Parkinson-White (WPW) syndrome. In AVRT, the existence of normal AV node and accessory pathway (AP) along with the atria and ventricles establish the electrical circuit that permits impulse re-entry. The incidence of multiple accessory pathways (MAP) is reported 3-15% and incidence of sudden cardiac death (SCD) in WPW syndrome is about 0.25% per year or 3% to 4% over a lifetime.

Case Description
We presented a case of Wolff-Parkinson-White Syndrome. A 28-year old man was admitted for evaluation of frequent episodes of palpitation. The diagnosis of WPW syndrome was established based on the 12 lead surface electrocardiogram (ECG). Echocardiography showed normal resting echocardiography then we performed electrophysiology study (EPS). We conducted the radiofrequency ablation (RFA) to the accessory pathway (AP). The challenging point of this case was multiple accessory pathways (APs) located at right posteroseptal and left lateral.

Discussion
Ablation of multiple accessory pathways (MAP) had a longer fluoroscopic time and large number of unsuccessful attempts than those with a single accessory pathway. We performed RFA at right posteroseptal and left lateral accessory pathway. The radiofrequency ablation has successfully eliminated both accessory pathways. In summary, we conclude that anatomical consideration, EP study, and the ablation strategy was important to improve the safety and success rate of RFA procedure.
C66. Paraaortic abscess complicating an Aerococcus Viridans Endocarditis: A Case Report
Authors: Farissa I P , Goma M S , Permitasari D A , Nugroho M A 
Published: April 2022

Abstract

Background
Infective Endocarditis (IE) associated with high mortality and complication despite improvement in its management. Paravalvular abscess known as feared complication of IE because its association with increased mortality. We describe a case of man with paravalvular abscess complicating IE undergone Aortic Valve Replacement.

Case Summary
A 42 years old man presented with exertional dyspneu since 2 weeks prior to admission, exaggerated with mild activities, accompanied with nausea, vomiting, swollen legs, and subfebrile for weeks. He was conscious and moderately ill with pressure 100/50 mmHg, regular pulse of 70, respiratory rate 25 times/minute, temperature was 37˚C, oxygen saturation was 94% on room air with end diastolic murmur grade II/4 in right upper sternal border. The laboratory result was leucocytosis (12.900/cu mm). The echocardiography revealed calcified in RCC and NCC aortic valve, RCC prolapse, severe aortic insufficiency, hyperechoic in paravalvular area. MSCT Cardiac revealed fistula originating from aortic root to a sac led to left ventricle. Sensitivity cultured revealed Aerococcus viridans. We gave antibiotics for 3 weeks before he undergone Aortic Valve Replacement. 1 month follow up, he had no more symptoms, and the prosthetic valve was normal.

Discussion
The diagnostic of IE remains challenging. It may present as an acute, rapidly progressive infection, but also as a subacute or chronic disease. Its complications need to be monitored vigilantly because it worsens the outcome. Antibiotics use for microbial eradication contributed by removing infected material surgically, might improve successful treatment for IE.
C68. Patient with Zero Coronary Calcium Score and Significant Stenosis in Left Anterior Descending Coronary Artery: a case report
Authors: Dylan R , Suratna K S K , Rampengan S H , Pangemanan J A 
Published: April 2022

Abstract

Background
Coronary heart disease is pathological process characterized by the accumulation of atherosclerotic plaque in the epicardial artery, either obstructive or non-obstructive. Coronary calcium score (CCS) detects and calculates coronary artery calcification (CAC) and CT coronary angiography (CTCA) allows evaluation of the coronary arteries anatomy for luminal stenosis due to atherosclerotic plaque with or without calcification.

Case Description
A 70 years-old man, admitted to the emergency department with a chief complain of chest pain. Physical examination was within normal limits. His treadmill stress testing was positive ischemic response one month prior. Then patient undergoing CTCA, the result was zero calcium score with 90-99% stenosis at proximal left anterior descending (LAD) due to soft plaque. Invasive coronary angiography (ICA) confirmed the CT findings and showed total occlusion with grade V thrombus in osteal LAD.

Discussion
A study showed that 1-2% of symptomatic patients with zero CAC potentially had obstructive CAD. It is supported with this report that the patient had typical chest pain with zero calcium score. CCTA has high sensitivity and negative predictive value for the detection of CAD but has a relatively low positive predictive value, especially for moderate severity coronary. In this report CTCA showed 90% -99% stenosis at the proximal LAD and correlate with ICA findings.
C76. Primary Cardiac Tumors : Benign or Malignant ? The Importance of Clinicopathologic Confirmation : a case series
Authors: Andryan D P , Lestiadi I D , Siswanto B B 
Published: April 2022

Abstract

Background
Cardiac tumor is a rare condition of space-occupying lesion mass in cardiac chamber. The incidence of clinically diagnosed Primary Cardiac Tumors is approximately 1,380/100 million individuals. Majority of cases are benign, with nearly half of them are cardiac myxoma. Although early clinical symptom of benign and malignant cardiac tumor are similar, the management and prognosis are much different.

Objective
To present serial cases of benign and malignant primary cardiac tumor.

Case Description
Mrs. RH, a 60-year-old woman referred to heart failure clinic National Cardiovascular Center Harapan Kita with chief complaint of short of breath on exercise. Echocardiography confirmed a huge mass obstructed her left atrium. She was hospitalized urgently with giant Left Atrial Myxoma with normal coronary artery, then underwent surgery of LA myxoma extirpation, Mitral Valve repair and Tricuspid Valve repair. Histopathological analysis confirmed of LA myxoma.
Mr. RBM, a 42-years-old man came to emergency unit at National Cardiovascular Center Harapan Kita with chief complaint shortness of breath and palpitation in about 1 month. A history of a cardiac tumor extirpation and mitral valve replacement was done in Penang Adventist hospital 10 months before. Transthoracal and transesophageal echocardiography found solid mass obstructing mechanical valve. Histopathology analysis showed undifferentiated cardiac sarcoma and against LA myxoma.

Discussion
Clinical course and management of cardiac tumor depends on early detection and histopathologic analysis. Although surgery is the cornerstone for cardiac tumor management, but confirmation of histopathologic findings is important.
C81. Pulse Dose Corticosteroid Improves Clinical Outcome in Pulmonary Hypertension Patient: A Potential of Immense Affordability and Availability Medication in Suburban Area
Authors: Sudirman A R , Sitompul S I 
Published: April 2022

Abstract

Background
Pulmonary hypertension (PH) in adolescence is a devastating diagnosis with significant morbidity and mortality. Despite limited literature exists on treating PH with anti-inflammatory medications in humans, hereby we present the case of prednisolone induced clinical outcomes improvement in PH patient.

Case Summary
A 20-year-old woman presented with exertional dyspnea. Her past-two-years medical history was remarkable for tricuspid regurgitation with multiple readmission. Upon arrival, her saturation-75% and BP-110/60. She was in respiratory distress with JVP increased and high-pitched-holosystolic murmur. Laboratory studies was unremarkable. The x-ray revealed cardiomegaly and ECG showing RVH-RAE. Initial echocardiography demonstrated TR-Vmax 4.55m/s and PR-Vmax 3.62m/s. The RVSP estimated around 107mmHg, which was highly suggestive for PH. Due to the aggressive nature of the disease, her condition deteriorated despite management with IV-furosemide-(40mg/d), beta-blocker-(2.5mg/d), and sodium beraprost-(60µg/d). Following days, a 5-days pulse-dose-steroid (methylprednisolone) at 2mg/kg/day was administered. Her condition improved with saturation from 50% to 90% and significant reduced in dyspnea. The steroid was tapering down for another 7 days and she was discharged for further referral.

Discussion
Inflammation plays unequivocal role in the pathogenesis of PH, which was involved in the development of pulmonary vascular remodeling. The possible mechanism of prednisolone were related with the inhibition of platelet-derived growth factor (PDGF)-induced accelerated proliferation and migration of pulmonary artery smooth muscle cell, and prevented the activation of NF-κB, key transcription factor that controls inflammation, cell-proliferation, and apoptosis. Thus, given the ready availability and features of this medication compared with other PH-medication, we decided to utilize steroid in this patient.
C93. Temporary Pacemaker Lead Insertion with Echocardiography Guided Technique in Emergency Setting: a Case Report
Authors: Kristanto H , Rizal A 
Published: April 2022

Abstract

Background
The implantation of the temporary pacemaker (TPM) must be done in symptomatic bradycardia to provide adequate heart rate and stabilize hemodynamic. Transvenous TPM is inserted under the fluoroscopy guidance. However, in an extraordinary situation, such as the unavailability of the catheterization laboratory, transvenous TPM insertion can be performed with echocardiography guiding.

Case Summary
A 27 years old male came to our ER with symtomatic bradicardia. Emergency procedure like medical treatment and transcutaneous pacing were done, but failed to increase heart rate. We planned transvenous pacing with fluoroscopy but the catheterization laboratory was not immediately available. Echocardiography guided temporary pacemaker were done in ER successfully and the patient was strabilized.

Discussion
Emergency transvenous pacemaker implantation with echocardiography guiding can be accomplished successfully in our case without complication. There are several techical aspect that we should consider in temporary pacemaker insertion without fluoroscopy. We use femoral access and with echocardiography guided in our case. The confirmation of the lead placement using fluoroscopy was needed to ensure that the tip of the electrode was in the proper position. Future research that focuses on the safety and effectiveness of the technique across the range of operator skill levels is needed.
Long-Term Effects of Crop Tree Release on Growth and Quality in White-Oak (Quercus alba L.)-Dominated Stands
Authors: Vogel Philip J , Lhotka John M , Stringer Jeffrey W 
Published: April 2022

Abstract
Crop tree release (CTR) can be an effective intermediate silvicultural treatment for culturing high-value stems in mixed hardwood stands. The lengthy rotation of hardwoods requires long-term evaluations if silvicultural treatment effectiveness is to be fully evaluated. Our study provides a 35-year evaluation of individual-tree and stand response to CTR imposed in small sawtimber-sized white-oak (Quercus alba L.)-dominated stands. The focus on white oak is justified based on the significant biologic and economic values of the species, and this study furthers our ability to optimize use of CTR as management tool for sustaining our oak resources. The replicated experiment included three treatment levels: 20 crop trees ac−1, 34 crop trees ac−1, and a control. Using a repeated-measures framework, we analyzed (1) how CTR affects growth and stem quality of white oak crop trees and (2) stand-level effects of CTR on basal area, stocking, and ingrowth. CTR increased crop tree diameter growth and proportion of crop trees reaching their maximum potential grade. However, crop tree diameter growth and proportion achieving maximum potential grade did not differ between the 20 and 34 crop trees ac−1 treatments. Finally, CTR stimulated stand-wide growth without altering the patterns of ingrowth density or species distributions.
Effects of edible whole citrus fruits on endogenous antioxidant enzymes of HepG2 cells
Authors: Sun Yujing , Liu Miaomiao , Tao Wenyang , Ye Xingqian , Sun Peilong 
Published: April 2022

Abstract
The effects of eating fresh citrus fruits including two varieties of mandarins, one of sweet oranges, one of grapefruit, two of pomelo, and one of kumquat cultivated in China on endogenous antioxidant enzymes were investigated by in vitro digestion and HepG2 cells. The correlations between enzyme activity and cell uptake of phytochemicals and cellular antioxidant capacities were analyzed. The results showed that most fresh citrus fruits increased the endogenous antioxidant activity. Bairoumiyou, Hongroumiyou, Ponkan, and Jinju after digestion significantly increased the activity of catalase (P&lt;0.05). Hongroumiyou, Bairoumiyou, Ponkan navel orange, and Jinju after digestion significantly increased glutathione peroxidases (GPxs) activity (P&lt;0.05), while Huyou and satsuma could not increase the activity of GPxs after digestion. Thioredoxin oxidoreductase activity was improved significantly by most of the digested whole citrus fruits except Ponkan (P&lt;0.05) and thioredoxin oxidoreductase added whole citrus fruits had a higher increase than added citrus fruits extracts. The results indicated that edible whole citrus fruits had similar effects as extracts on enzymes.
A Gelfand-Type Duality for Coarse Metric Spaces With Property A
Authors: Braga Bruno M , Vignati Alessandro 
Published: April 2022

Abstract
We prove the following two results for a given uniformly locally finite metric space with Yu’s property A: 1. The group of outer automorphisms of its uniform Roe algebra is isomorphic to its group of bijective coarse equivalences modulo closeness. 2. The group of outer automorphisms of its Roe algebra is isomorphic to its group of coarse equivalences modulo closeness. The main difficulty lies in the latter. To prove that, we obtain several uniform approximability results for maps between Roe algebras and use them to obtain a theorem about the “uniqueness” of Cartan masas of Roe algebras. We finish the paper with several applications of the results above to concrete metric spaces.
Connecting plant phenotyping and modelling communities: lessons from science mapping and operational perspectives
Authors: Saint Cast Clément , Lobet Guillaume , Cabrera-Bosquet Llorenç , Couvreur Valentin , Pradal Christophe , Tardieu François , Draye Xavier 
Published: April 2022

Abstract
Plant phenotyping platforms generate large amounts of high-dimensional data at different scales of plant organization. The possibility to use this information as inputs of models is an opportunity to develop models that integrate new processes and genetic inputs. We assessed to what extent the phenomics and modelling communities can address the issues of interoperability and data exchange, using a science mapping approach (i.e. visualization and analysis of a broad range of scientific and technological activities as a whole). In this paper, we (i) evaluate connections, (ii) identify compatible and connectable research topics and (iii) propose strategies to facilitate connection across communities. We applied a science mapping approach based on reference and term analyses to a set of 4332 scientific papers published by the plant phenomics and modelling communities from 1980 to 2019, retrieved using the Elsevier’s Scopus database and the quantitative-plant.org website. The number of papers on phenotyping and modelling dramatically increased during the past decade, boosted by progress in phenotyping technologies and by key developments at hardware and software levels. The science mapping approach indicated a large diversity of research topics studied in each community. Despite compatibilities of research topics, the level of connection between the phenomics and modelling communities was low. Although phenomics and modelling crucially need to exchange data, the two communities appeared to be weakly connected. We encourage these communities to work on ontologies, harmonized formats, translators and connectors to facilitate transparent data exchange.
Effects of ferulic acid on the growth performance, antioxidant capacity, and intestinal development of piglets with intrauterine growth retardation
Authors: Wan Jin , Yu Qiong , Luo Junqiu , Zhang Li , Ruan Zheng 
Published: April 2022

Abstract
Neonates with intrauterine growth retardation (IUGR) are prone to suffer from delayed postnatal growth and development during the early stages of life. Ferulic acid (FA) is a phenolic compound that is abundantly present in fruits and vegetables and has various health benefits. Hence, we explored whether FA supplementation could favorably affect the growth performance, antioxidant capacity, and intestinal development of piglets with IUGR. In total, eight normal-birth-weight (NBW) piglets and 16 piglets with IUGR (age, 7 d) were assigned to be fed either basic formula milk (NBW and IUGR groups, respectively) or basic formula milk supplemented with 100 mg/kg FA (IUGR + FA group) for 21 d. At necropsy, the serum and intestinal tissues were collected. FA supplementation increased (P &lt; 0.05) the feed conversion ratio and serum total superoxide dismutase and catalase activities in piglets with IUGR. Moreover, FA supplementation elevated (P &lt; 0.05) the duodenal lactase and maltase activities, jejunal villus height and jejunal maltase activity but reduced (P &lt; 0.05) the duodenal crypt depth and duodenal and jejunal cell apoptosis, cleaved cysteinyl aspartic acid protease-3 (caspase-3) content and cleaved caspase-9 content in piglets with IUGR. In summary, FA supplementation could elevate antioxidant capacity and facilitate intestinal development, thus resulting in increased feed efficiency in piglets with IUGR.
Analysis of fourth-grade fluid model over a stretchable surface with Riga plate subject to permeable medium
Authors: Hua Bian , Shah Faisal , Khan M Ijaz , El-Zahar Essam Roshdy , Farooq Shahid , Khan Sami Ullah , Guedri Kamel , Wu Wen-jing 
Published: April 2022

AbstractThe current investigation is concerned with the rheological impact of fourth-grade confined by Riga surface. The flow behaviour is analysed over a Riga plate in the presence of stagnation point and porous medium. The relevant similarity variables and corresponding boundary conditions are adopted to model the current problem. The highly non-linear coupled differential system is via optimal homotopy scheme. The outcomes of relevant dimensionless parameters on the velocity profile have been visualized with physical exploration. It is observed from the obtained outcomes that the fluid velocity declines against rising estimations of modified magnetic variable and inverse Darcy number. The increasing velocity change is noted for boosting values of third-grade fluid parameter. Moreover, the velocity pattern for fourth-grade material is comparatively higher than viscous, second-grade, and third-grade materials. The comparative analysis against obtained simulations is also listed.
Current trend of radiotherapy for glioblastoma in the elderly: a survey study by the brain tumor Committee of the Korean Radiation Oncology Group (KROG 21–05)
Authors: Wee Chan Woo , In Yoon Hong , Lee Sea-Won , Lim Do Hoon 
Published: April 2022

Abstract

Background
To investigate the current variability in radiotherapy practice for elderly glioblastoma patients.

Methods
A questionnaire comprising general information on elderly glioblastoma, treatment selection, radiotherapy and 16 clinical case-scenario-based questions (based on age, performance, extent of resection and MGMT promoter methylation) was sent to brain tumor radiation oncologists.

Results
Twenty-one responses were recorded. Most (71.4%) stated that 70 years is an adequate cut-off for ‘elderly’ individuals. The most preferred hypofractionated short-course radiotherapy schedule was 40–45 Gy over 3 weeks (81.3%). The median margin for high-dose target volume was 5 mm (range, 0–20 mm) from the T1-enhancement for short-course radiotherapy. The case-scenario-based questions revealed a near-perfect consensus on 6-week standard radiotherapy plus concurrent/adjuvant temozolomide as the most appropriate adjuvant treatment in good performing patients aged 65–70 years, regardless of surgery and MGMT promoter methylation. Notably, in 75-year-old patients with good performance, the most preferred treatment was 6-week radiotherapy (81.0–90.5%) plus concurrent/adjuvant temozolomide (71.4–95.2%) rather than short-course radiotherapy or radiotherapy alone. Although the use of 3-week short-course radiotherapy increased with age and decreased performance status (all P &lt; 0.05), 6-week radiotherapy was adopted in a significant proportion of responders (14.3–23.8%) even for wheelchair-bound, 75-year-old patients. Temozolomide use was affected by age, performance and MGMT promoter (all P &lt; 0.05).

Conclusions
A high level of consensus was observed in treating elderly glioblastoma patients with good performance status. However, the variability increased, especially for older patients and those with poor performance. This study serves as a basis for designing future clinical trials in elderly glioblastoma.
Older Refugees and Internally Displaced People in African Countries: Findings from a Scoping Review of Literature
Authors: Böcker Anita , Hunter Alistair 
Published: April 2022

Abstract
By and large, the attention and resources of governments, NGOs, and humanitarian actors have been directed at children and working-age displaced people, ignoring the needs and perspectives of displaced elders. Africa is the continent with the largest number of displaced people aged 60 and over. To help achieve equity and better representation for this latter group, it appears essential to delineate and clarify the evidence base on displaced elders in Africa. We systematically searched bibliographic databases in the social and health sciences. One hundred forty-one papers met our inclusion criteria globally, of which 16 were based on data collected in African countries. The scoping review establishes that the main focus has been the specific vulnerabilities faced by older African displaced people, particularly with regard to physical health and the erosion of social support systems. Contrary to research on older displaced populations elsewhere, studies on the mental health of displaced elders in Africa are lacking. Similarly, more priority should be given to phenomenological and life course approaches to better understand the lived experience of displaced African elders.