bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of isoproterenol infusion during catheter ablation of atrial fibrillation with outcomes: insights from the UC San Diego AF Ablation Registry
Authors: Aldaas Omar M. , Darden Douglas , Mylavarapu Praneet S. , Han Frederick T. , Hoffmayer Kurt S. , Krummen David , Ho Gordon , Raissi Farshad , Feld Gregory K. , Hsu Jonathan C. 
Published: December 2022

Abstract

Background
High-dose isoproterenol infusion is a useful provocative maneuver to elicit triggers of atrial fibrillation (AF) during ablation. We evaluated whether the use of isoproterenol infusion to elicit triggers of AF after ablation is associated with differential outcomes.

Methods
We performed a retrospective study of all patients who underwent de novo radiofrequency catheter ablation of AF enrolled in the University of California, San Diego AF Ablation Registry. The primary outcome was freedom from atrial arrhythmias on or off antiarrhythmic drugs (AAD).

Results
Of 314 patients undergoing AF ablation, 235 (74.8%) received isoproterenol while 79 (25.2%) did not. Among those who received isoproterenol, 11 (4.7%) had additional triggers identified. There were no statistically significant differences in procedure time (p = 0.432), antiarrhythmic drug use (p = 0.289), procedural complications (p = 0.279), recurrences of atrial arrhythmias on or off AAD [adjusted hazard ratio (AHR) 0.92 (95% CI 0.58–1.46); p = 0.714], all-cause hospitalizations [AHR 1.00 (95% CI 0.60–1.67); p = 0.986], or all-cause mortality [AHR 0.14 (95% CI 0.01–3.52); p = 0.229] between groups.

Conclusions
In this registry analysis, use of isoproterenol is safe but was not associated with a reduction in recurrence of atrial arrhythmias.
A Function Approximation Approach for Parametric Optimization
Authors: De Marchi Alberto , Dreves Axel , Gerdts Matthias , Gottschalk Simon , Rogovs Sergejs 
Published: December 2022

AbstractWe present a novel approach for approximating the primal and dual parameter-dependent solution functions of parametric optimization problems. We start with an equation reformulation of the first-order necessary optimality conditions. Then, we replace the primal and dual solutions with some approximating functions and find for some test parameters optimal coefficients as solution of a single nonlinear least-squares problem. Under mild assumptions it can be shown that stationary points are global minima and that the function approximations interpolate the solution functions at all test parameters. Further, we have a cheap function evaluation criterion to estimate the approximation error. Finally, we present some preliminary numerical results showing the viability of our approach.
Vascular anomalies in patients with growth hormone-secreting pituitary adenomas: illustrative case report and systematic review of the literature
Authors: Spille Dorothee Cäcilia , Vorona Elena , Catalino Michael P. , Reuter Gilles , Beckers Albert , Holling Markus , Fava Arianna , Stummer Walter , Laws Edward R. , Suero-Molina Eric 
Published: December 2022

Abstract
Purpose
Endonasal resection is the first-line treatment for patients harboring growth hormone (GH)-secreting pituitary adenomas. The complexity of the parasellar neurovascular structures makes pre-operative diagnostic imaging essential to understanding the anatomy of this region. We aimed to describe vascular anomalies in acromegalic patients and emphasize their relevance for surgery and preoperative planning.

Methods
A systematic review following the PRISMA statement was performed in July 2021.

Results
Thirty-three studies were evaluated. Elevated GH and insulin-like growth factor-1 (IGF-1) levels are linked to the occurrence of cardiovascular risk factors. This is attributed to endothelial dysfunction, mainly caused by changes in flow-mediated dilatation (FMD), which is probably the main cause of vascular anomalies in acromegaly. The occurrence of protrusions of the internal carotid artery (ICA) (35–53%), a narrow intercarotid distance, and an asymmetrical course was described. In 13–18% of acromegalic patients, the presence of an intracerebral aneurysm could be reported (incidence in the general population:0.8–1.3%). The selected studies were however performed with a small patient sample (range:1–257).
We present a case report of a 57y/o male patient with anomalies of the ICA (“kissing carotid arteries”) harboring a GH-secreting adenoma, which was resected via an endoscopic endonasal approach.

Conclusions
There is an association between acromegaly and endothelial dysfunction, which increases cardiovascular risk factors and vascular anomalies. Preoperative vascular imaging, e.g., CT angiography, should be implemented as a standard to identify patients at risk and estimate surgical morbidity. However, no evidence-based recommendations exist so far, so future studies are necessary.
PerHeFed: A general framework of personalized federated learning for heterogeneous convolutional neural networks
Authors: Ma Le , Liao YuYing , Zhou Bin , Xi Wen 
Published: December 2022

AbstractIn conventional federated learning, each device is restricted to train a network model of the same structure. This greatly hinders the application of federated learning where the data and devices are quite heterogeneous because of their different hardware equipment and communication networks. At the same time, existing studies have shown that transmitting all of the model parameters not only has heavy communication costs, but also increases risk of privacy leakage. We propose a general framework for personalized federated learning (PerHeFed), which enables the devices to design their local model structures autonomously and share sub-models without structural restrictions. In PerHeFed, a simple-but-effective mapping relation and a novel personalized sub-model aggregation method are proposed for heterogeneous sub-models to be aggregated. By dividing the aggregations into two primitive types (i.e., inter-layer and intra-layer), PerHeFed is applicable to any combination of heterogeneous convolutional neural networks, and we believe that this can satisfy the personalized requirements of heterogeneous models. Experiments show that, compared to the state-of-the-art method (e.g., FLOP), in non-IID data sets our method compress ≈ 50% of the shared sub-model parameters with only a 4.38% drop in accuracy on SVHN dataset and on CIFAR-10, PerHeFed even achieves a 0.3% improvement in accuracy. To the best of our knowledge, our work is the first general personalized federated learning framework for heterogeneous convolutional networks, even cross different networks, addressing model structure unity in conventional federated learning.
Optimization of the cooling strategy during cryogenic milling of Ti-6Al-4 V when applying a sub-zero metalworking fluid
Authors: Gutzeit Kevin , Berndt Maximilian , Schulz Jonas , Müller Daniel , Kirsch Benjamin , von Harbou Erik , Aurich Jan C. 
Published: December 2022

AbstractDue to an excellent ratio of high strength to low density, as well as a strong corrosion resistance, the titanium alloy Ti-6Al-4 V is widely used in industrial applications. However, Ti-6Al-4 V is also a difficult-to-cut material because of its low thermal conductivity and high chemical reactivity, especially at elevated temperatures. As a result, machining Ti-6Al-4 V is characterized by high thermal loads and a rapidly progressing thermo-chemical induced tool wear. An adequate cooling strategy is essential to reduce the thermal load and therefore tool wear. Sub-zero metalworking fluids (MWF) which are applied at liquid state but at supply temperatures below the ambient temperature, offer great potential to significantly reduce the thermal load when machining Ti-6Al-4 V. Within the presented research, systematically varied sub-zero cooling strategies are applied when milling Ti-6Al-4 V. The influences of the supply temperature, as well as the volume flow and the outlet velocity are investigated aiming at a reduction of the thermal loads that occur during milling. The milling experiments were recorded using high-speed cameras in order to characterize the impact of the cooling strategies and resolve the behavior of the MWF. Additionally, the novel sub-zero cooling approach is compared to a cryogenic CO2 cooling strategy. The results show that the optimized sub-zero cooling strategy led to a sufficient reduction of the thermal loads and does outperform the cryogenic cooling even at elevated CO2 mass flows.
Transcriptional analysis reveals formation of axillary solitary hook in vine plant Uncaria rhynchophylla
Authors: Wan Lingyun , Pan Limei , Song Lisha , Fu Jine , Huang Qiulan , Ji Xiaowen , Wei Shugen , Zhang Zhanjiang 
Published: December 2022

AbstractThe hook of Uncaria rhynchophylla is an important external phenotype representing the quality of Gou-Teng. The hook formation pattern of U. rhynchophylla displays a unique feature that solitary hook and opposite hooks alternately occur in the leaf axils forming a liner series. The solitary hook only grows on the lower side of the leaf axil, resulting from the decline in the total yield of hooks. However, the reasons for solitary hook formation in U. rhynchophylla are not clear. Therefore, a survey on the molecular mechanisms of solitary hook formation needs to be performed urgently. We obtained 250.67 million high-quality clean reads from the lower side of axillary stem segments (HS) and the upper side of axillary stem segments (HSCK) libraries. We detected 42 DEGs (differentially expressed genes) between HS and HSCK libraries; 11 were down-regulated, and 31 were up-regulated. Gene ontology functional classification of the DEGs indicated that they included two genes that encoded LAZY1 related to the regulation of polar auxin transport, two genes that encoded AUX/IAA and AP2/ERF related to plant hormone signaling transduction, and two genes that encoded F3H related to the flavone synthase activity. These six genes were associated with lateral polar auxin transport (PAT) regulation, and their expression level had a high correlation with the pattern of IAA distribution upon gravity stimulation. And the inhibition of solitary hook development was observed after treatment with N-1-naphthylphthalamic acid (NPA) or quercetin, which was known as the polar auxin inhibitor. The above findings might provide new information about the molecular mechanisms of regulation of lateral PAT in the axillary bud development process under gravity.
Thermoelastic analysis of semiconducting solid sphere based on modified Moore-Gibson-Thompson heat conduction with Hall Effect
Authors: Kaur Iqbal , Singh Kulvinder 
Published: December 2022

AbstractThe main contribution of this study is to present a unique new mathematical model of photo-thermoelastic interactions with Hall current effect in an infinite semiconducting solid sphere due to high magnetic field acting along its axis. A variable heat flux is applied to the boundary surface of a solid semiconductor sphere. A generalized modified Moore-Gibson-Thompson-Photo-Thermal (MGTPT) theory is used to express the governing equations. In the Green Nagdhi (GN III) model, a thermal relaxation parameter and carrier density parameter is introduced to obtain the new modified Moore-Gibson-Thompson equation (MGT). This mathematical model is solved using Laplace's transforms. Various components of displacement, thermodynamic temperature, conductive temperature, carrier density and axial stress as well as couple stress are obtained in the transformed domain. To get the solution in physical domain, numerical inversion techniques have been employed. The effect various thermoelasticity theories and Hall current is shown graphically on the physical quantities.
Optimizing the shape anisotropy of gold nanoparticles for enhanced light harvesting and photocatalytic applications
Authors: Antony Jibin , Bandyopadhyay Sulalit , Yang Jia , Rønning Magnus 
Published: December 2022

AbstractHybrid nanoparticles (NP) of bismutite nanodisks (BSC ND) with gold nanoparticles (Au NP) of different aspect ratios (AR), such as spheres, rods and etched rods were synthesized via a facile sonochemical method. To better control the shapes of Au NP deposited on the substrate, these were pre-synthesized prior to the deposition using a modified seed mediated growth method by altering the pH and supersaturation of the growth solution. The shift in the peak position and shape of the localized surface plasmon resonance (LSPR) absorption band associated with fine-tuning of the shape of Au NP, led to enhanced light harvesting capabilities of the hybrid. Introducing shape anisotropy in the NP brought about narrowing of bandgap and lowering of PL intensity in the hybrids, suggesting better electronic contact of the NP with BSC, and effective suppression of recombination effects. Hybrids of BSC with Au nanorods showed 14% improved degradation of methylene blue (MB) dye compared to the hybrids with nanospheres. With this study, we provide a novel promising strategy to maximize the light harvesting capacity of semiconductors by tailoring the AR of Au NP, for improved solar to chemical energy conversion.
Graphical abstract
Imperfect Patients: Disparities in Treatment of Stroke Patients with Premorbid Disability
Authors: Cruise Cera , Mfoafo M’Carthy Nicole , Ganesh Aravind , Lashewicz Bonnie 
Published: December 2022

ABSTRACT:Background:Despite the high proportion of stroke patients with a pre-existing impairment, patients with disabilities are often excluded from stroke treatment trials. Trials are designed for “perfect patients”: patients who are functionally independent and thus generally younger with fewer comorbidities; ironically, such patients are less likely to experience stroke than those with premorbid disability. Exclusionary practices in trials may translate into disparities in stroke care in practice. Through a review of literature, our purpose is to illuminate how people with disabilities are treated across the care continuum following a stroke.Methods:We completed a qualitative systematized review of articles pertaining to the care of patients with premorbid disability and stroke and their outcomes. Using a critical disability studies' theoretical lens, we analyzed inequity across the stroke care continuum.Findings:Among 24 included studies, we found evidence that people with disabilities did not receive equitable access to treatment ranging from being admitted to stroke units to receiving post-stroke rehabilitation. However, observational studies suggest that stroke therapies may be beneficial in selected patients with disabilities when measures of success are framed more achievable (e.g. return to pre-stroke status). This leaves us concerned about how people with pre-existing impairments might be structurally disabled within current systems of stroke care.Conclusion:We use our critical disability studies' theoretical lens to argue that an intersectional approach to stroke treatment is much needed if we are to remedy structural inequities embedded throughout the care continuum.
Military Response to Medical Crises—Consensus Recommendations for Military–Civilian Transitions of Care
Authors: Goolsby Craig , Schuler Keke , Tilley Laura , Zebrowski Alexis , Dacuyan-Faucher Nicole , Kim Claire , Redlener Michael 
Published: December 2022

Abstract

Objective:
The threat that New York faced in 2020, as the COVID-19 pandemic unfolded, prompted an unprecedented response. The US military deployed active-duty medical professionals and equipment to NYC in a first of its kind response to a “medical” domestic disaster. Transitions of care for patients surfaced as a key challenge. Uniformed Services University and the Icahn School of Medicine at Mount Sinai hosted a consensus conference of civilian and military healthcare professionals to identify care transition best practices for future military-civilian responses.

Methods:
We performed individual interviews followed by a modified Delphi technique during a two-day virtual conference. Patient transitions of care emerged as a key theme from pre-conference interviews. Twelve participants attended the two-day virtual conference and generated best practice recommendations from an iterative process.

Results:
Participants identified 19 recommendations in 10 “sub-themes” related to patient transitions of care: needs assessment and capability analysis; unified command; equipment; patient handoffs; role of in-person facilitation; dynamic updates; patient selection; patient tracking; daily operations; and resource typing.

Conclusions:
The COVID-19 pandemic resulted in an unprecedented military response. This study created 19 consensus recommendations for care transitions between military and civilian healthcare assets that may be useful in future military-civilian medical engagements.
Big-Five model of personality and word formation: role of open-mindedness in semantic transparency and economy of expression
Authors: Kačmár Pavol , Körtvélyessy Lívia 
Published: December 2022

AbstractAs word formation can be conceptualized as an act of creativity with considerable space for differences among speakers, we present pilot research aimed at the examination of the role of Big-Five personality domains in the formation of new complex words. The sample consisted of 197 participants who underwent a word formation test and a personality assessment via The Next Big-Five Inventory. The results indicate that when ordinal regression is conducted with an aim of accounting for age and gender, open-mindedness is shown as a potentially important predictor – it positively predicted economy of expression and negatively predicted semantic transparency. Furthermore, a more nuanced approach differentiating three facets of open-mindedness shows that creative imagination predicted semantic transparency positively while esthetic sensitivity predicts semantic transparency negatively (the reverse is true for the economy of expression). These findings provide a promising starting point for future research.
ON THE FIBRES OF AN ELLIPTIC SURFACE WHERE THE RANK DOES NOT JUMP
Authors: CARO JERSON , PASTEN HECTOR 
Published: December 2022

AbstractFor a nonconstant elliptic surface over
$\mathbb {P}^1$
defined over
$\mathbb {Q}$
, it is a result of Silverman [‘Heights and the specialization map for families of abelian varieties’, J. reine angew. Math.342 (1983), 197–211] that the Mordell–Weil rank of the fibres is at least the rank of the group of sections, up to finitely many fibres. If the elliptic surface is nonisotrivial, one expects that this bound is an equality for infinitely many fibres, although no example is known unconditionally. Under the Bunyakovsky conjecture, such an example has been constructed by Neumann [‘Elliptische Kurven mit vorgeschriebenem Reduktionsverhalten. I’, Math. Nachr.49 (1971), 107–123] and Setzer [‘Elliptic curves of prime conductor’, J. Lond. Math. Soc. (2)10 (1975), 367–378]. In this note, we show that the Legendre elliptic surface has the desired property, conditional on the existence of infinitely many Mersenne primes.
QUISTCLOSE TRUSTS FROM A CORPORATE INSOLVENCY PERSPECTIVE: A POSITIVE AND NORMATIVE ANALYSIS
Authors: Hofri-Winogradow Adam S. , David Gal 
Published: December 2022

AbstractLeading cases show Quistclose trusts being used by companies nearing insolvency. Their use in this context raises serious normative problems: it may prefer the beneficiary to the company's other creditors, and creates a misleading impression that trust funds are in fact free of trust. Building on the emergent normative literature on Quistclose trusts, we first examine which Quistclose trusts are currently allowed under company law and the law of corporate insolvency. We then discuss the normative question as to which Quistclose trusts should be allowed, given the principles of these branches of the law.
How we do it: using the nasion as a landmark for identifying the anterior ethmoidal artery
Authors: Patel T A , Lubbe D 
Published: December 2022

AbstractBackgroundIn severe refractory epistaxis, the anterior ethmoidal artery may need to be ligated. Previously described endonasal or transorbital approaches are not always effective, or they have suboptimal aesthetic outcomes. This paper describes a safe and effective surgical technique, with a consistent landmark allowing quick identification.Technical descriptionA transcaruncular incision is made, oriented medially in the direction of the medial orbital wall towards the level of the nasion. Once onto bone, a subperiosteal plane is developed and an endoscope is used to dissect posteriorly at the level of the nasion, until the anterior ethmoidal artery is identified, and subsequently ligated.ConclusionThe nasion is an easy, constant landmark to use for ligation of the anterior ethmoidal artery in refractory epistaxis. The traditional method of identifying the anterior ethmoidal artery is not applicable or constant enough for use during the transorbital approach. The described technique avoids injury to surrounding structures and has a satisfactory aesthetic outcome.
Mining tourism in abandoned and existing mines in the Swedish Far North
Authors: Byström Joakim 
Published: December 2022

Abstract
The Swedish North is sometimes described as a resource periphery, while others choose to label it a pleasure periphery. Regardless of the terms used, the region is characterised by problems such as out-migration and demographic issues. This study investigates why there are such different perceptions of the same area, and whether there is any contradiction between extractive resource industries and the tourism industry. This is done by collecting visitor data from mining companies and conducting interviews with a variety of respondents in three mining communities in northern Sweden. Mining tourism is a phenomenon occurring in this region and can be regarded as a context in which the two main narratives meet while being a rather overlooked form of tourism. This is partly due to the low level of knowledge regarding its impacts, but also to a somewhat established idea of mining tourism as a “bad” form of tourism. Individuals’ perceptions of mining tourism as a phenomenon seem to be highly value-related and influenced by both location and occupation. As such, various opinions can be explained by social exchange theory, which proposes that attitudes will be influenced by individuals’ evaluation of outcomes for themselves and their community. In this paper, the emergence of mining tourism is understood as knowledge creation rooted in a regional path dependency on mining and tourism. Hence, mining tourism becomes a new regional tourism product that contributes to tourism, at least in terms of standard technical visits and, at best, a well-developed tourist attraction that appeals to visitors in quantities similar to iconic regional attractions such as the Icehotel. Then again, a tourism industry selling dreams of “untouched nature” argues that this tourism product produces “bad imaging”.
Greenwashing and public demand for government regulation
Authors: Kolcava Dennis 
Published: December 2022

AbstractEnvironmental governance in many high-income democracies relies to some extent on self-regulation by the private sector. Yet, this policy mode is contested and proponents of top-down government regulation argue that voluntary corporate sustainability commitments remain shallow and rarely are more than greenwashing. I assess to what extent firms’ business conduct is subject to societal checks and balances, in particular, whether public support for regulation constitutes a control mechanism of corporate contributions to environmental goods. I rely on an original survey experiment (N = 2112) conducted with a representative sample of the Swiss voting population. The analysis shows that accusing firms of greenwashing reduces both citizens’ perceived effectiveness of self-regulation and perceived synergy of corporate profits and environmental protection. However, this attitudinal shift only translates into modest updates in respondents’ policy preferences. As a result, short-run shifts in public support for regulation are an unlikely societal control mechanism of business conduct.