bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANTROPOLOGIA E FEMINISMO: UMA DISCUSSÃO NECESSÁRIA NA SOCIEDADE
Authors: Martins Gabrielle Aparecida , Cezar Bonin Joel 
Published: February 2022

A pesquisa em questão pretende debater a antropologia e sua relação com o feminismo, demonstrando como essas vertentes se diferenciam, necessitando atentar-se sobre a questão das mulheres e o seu trabalho dentro da ciência da Antropologia. O problema da pesquisa gira em torno da importância de definir um termo que envolva as mulheres em relação aos estudos sociais. O objetivo geral do trabalho é pontuar um debate acerca da antropologia e do feminismo. A presente pesquisa é considerada, exclusivamente, de cunho bibliográfico, a qual se utiliza de vários autores, que abordam o assunto de maneira enriquecedora, buscando delimitar as questões da Antropologia, feminismo e a ideia do neologismo da “Antropologia Feminina”. Os resultados desejados foram alcançados, visto que, com a pesquisa aprofundada sobre o tema em pauta, pode-se compreender melhor a necessidade do desenvolvimento de um novo termo que coloque as mulheres como elementos principais nos escritos antropológicos.
PALAVRAS CHAVE: Antropologia. Feminismo. Antropologia Feminista.
ABSTRACT
The research in question intends to debate anthropology and the relationship with feminism, demonstrating how these aspects differ, needing attention to the issue of women and their work within Anthropology science. The research problem revolves around the importance of defining a term that involves women in relation to social studies. The general objective of the work is to punctuate a debate about anthropology and feminism. The present research is considered, exclusively, of bibliographic nature, in which it uses several authors, who approach the subject in an enriching way, seeking to delimit the issues of Anthropology, Feminism, Female Anthropology and the idea of the neologism of "Female Anthropology". The results were achieved, since, with in-depth research on the topic at hand, one can better understand the need to develop a new term that places women as the main elements in anthropological writings.
Keywords: Anthropology. Feminism. Feminist Anthropology.
CONTRATOS NA INTERNET E A TRANSNACIONALIZAÇÃO DOS CONSUMIDORES
Authors: Piffer Carla , Schoning Raquel 
Published: February 2022

O presente artigo possui como objetivo geral analisar os contratos na Internet e a transnacionalização dos consumidores, partindo-se do pressuposto de que tais negócios jurídicos transpassam fronteiras ante os efeitos da globalização na Era da Informação. Considerando o consumo na Internet um novo direito fundamental transnacional, transindividual e transfronteiriço, busca-se investigar, à luz dos princípios contratuais, a demanda transnacional em que estes estão inseridos. Para a realização desta pesquisa foi utilizado, na fase de investigação, o método indutivo e na fase de tratamento de dados, o método cartesiano, seguidos, quando do relato dos resultados, da base lógica foi indutiva.
Palavras-chave: Contratos; Internet; Meio eletrônico; Consumidores; Transnacionalidade.
Pelatihan Kecakapan Masyarakat Dalam Pengembangan Daya Tarik Wisata dan Pemanduan Perjalanan Wisata Desa di Desa Durian Demang Kabupaten Bengkulu Tengah
Authors: Marianata Anita , Perdana Dionni Ditya 
Published: February 2022

Pengabdian ini dilakukan di Desa Durian Demang, Kabupaten Bengkulu Tengah. Tujuan dari pengabdian ini meliputi (1) pelatihan kecakapan masyarakat dalam pengembangan daya tarik wisata dan pemanduan perjalanan wisata desa; (2) penambah wawasan bagi masyarakat mengenai pentingnya pengembangan daya tarik wisata dan pemanduan perjalanan wisata desa. Pengumpulan data dilakukan dengan cara observasi, wawancara, dan focus group discussion (FGD). Hasil pengabdian menunjukkan Desa Durian Demang melalui BUMDes sudah mengalokasikan untuk pengembangan wisata Bukit Kandis, pembahasan materi dimulai dari kepengurusan desa wisata, tantangan dan peluang desa wisata, dan kesiapan masyarakat untuk berperan aktif dalam keberhasilan desa wisata.Kata kunci: Desa Wisata, Bukit Kandis, Masyarakat Lokal
Pengenalan Oximeter sebagai Deteksi Kejenuhan Oksigen dalam Darah Kepada Satgas Covid-19 Kalurahan Serut, Gunung Kidul
Authors: Salamah Umi , Kusuma Damar Yoga 
Published: February 2022

Since the emergence of Covid-19 in Indonesia in early 2020, it has spread throughout Indonesia, including rural areas. The Serut District, which is a border area, namely the Klaten district with Gunung Kidul, cannot be separated from the spread of Covid-19. The condition of the people of Serut Village, which is a genuine rural community, causes a lack of understanding of the dangers of the virus. The confusion of news in the mass media and social media has made the understanding of Covid-19 blurry. One of them is a non-invasive oxygen saturation detection system technology using an oximeter to monitor blood health conditions. This is very important, especially for patients who have confirmed Covid-19 and are self-isolating at home. In this service, the implementing team collaborates with the Serut Village government and the ranks of the Covid-19 task force to mitigate Covid-19 in the Serut Village area. The programs that will be implemented include providing materials and demonstrations for detecting oxygen saturation in the blood using an oximeter to the Covid-19 task force. The provision of materials and demonstrations will be continued with data sampling and analysis to the people of Serut Village. This program aims to introduce the system of measuring oxygen saturation in the blood and how to measure it independently. This is very important considering that oxygen saturation in the blood is one of the parameters in Covid-19 patients. Keywords: Oximeter; Blood Oxygen Saturation ;Satgas Covid-19; Kalurahan Serut
PERANAN GURU PENDIDIKAN AGAMA ISLAM DALAM MENGATASI KESULITAN PESERTA DIDIK MEMBACA AL-QUR’AN DI SMP NEGERI 3 TANIWEL KECAMATAN TANIWEL BARAT KABUPATEN SERAM BAGIAN BARAT
Authors: Assel Rini 
Published: February 2022

Abstract: The purpose of this study was to determine the role of Islamic religious education teachers in overcoming the difficulties of students reading the Qur'an at SMP Negeri 3 Taniwel, West Taniwel District, West Seram Regency. The type of research is descriptive qualitative research. The results of the study indicate that the role of Islamic religious education teachers in overcoming the difficulties of students reading the Koran at SMP Negeri 3 Taniwel includes; a. The teacher as a teacher, the role of the teacher as a coach, the teacher as an example. Factors supporting the implementation of the duties or roles of Islamic religious education teachers are facilities and infrastructure (learning media), teacher awareness in carrying out responsibilities and student learning motivation. Inhibiting factors are the lack of time allocation and lack of parental attention. Keywords: Islamic Religious Education, Difficulty Reading The Qur'an. Abstrak: Tujuan penelitian ini untuk mengetahui peranan guru pendidikan agama Islam dalam mengatasi kesulitan peserta didik membaca al-Qur’an di SMP Negeri 3 Taniwel Kecamatan Taniwel Barat Kabupaten Seram Bagian Barat. Tipe penelitian adalah penelitian deskriptif kualitatif. Hasil penelitian menunjukkan bahwa peranan guru pendidikan agama Islam dalam mengatasi kesulitan peserta didik membaca al-Qur’an SMP Negeri 3 Taniwel meliputi; a. Guru sebagai pengajar, Peran guru sebagai pelatih, Guru sebagai teladan. Faktor pendukung pelaksanaan tugas atau peranan guru pendidikan agama islam adalah Sarana dan prasarana (media pembelajaran), Kesadaran guru dalam melaksanakan tanggung jawab dan Motivasi belajar peserta didik. Faktor penghambat yakni Kurangnya alokasi waktu dan Kurangnya perhatian orang tua.
Molecular Patterns Based on Immunogenomic Signatures Stratify the Prognosis of Colon Cancer
Authors: Shen Cong , Luo Cong , Xu Zhijie , Liang Qiuju , Cai Yuan , Peng Bi , Yan Yuanliang , Xia Fada 
Published: February 2022

Background: Colon cancer is an aggressive and heterogeneous disease associated with high morbidity and mortality. The immune system is intimately involved in tumorigenesis and can influence malignant properties at the protein, epigenetic, and even genomic levels by shaping the tumor immune microenvironment (TIM). However, immune-related molecules that can effectively predict the prognosis of colon cancer remain under exploration.Methods: A total of 606 patients from TCGA and GEO databases were employed in our study, in which 429 cases were set as the training cohort and 177 were defined as the validation cohort. The immune infiltration was evaluated by ESTIMATE, TIMER, and CIBERSORT algorithms. The risk signature was constructed by LASSO Cox regression analysis. A nomogram model was generated subsequent to the multivariate Cox proportional hazards analysis to predict 1-, 3-, and 5-year survival of patients with colon cancer.Results: Infiltrating immune cell profiling identified two colon cancer clusters (Immunity_L group and Immunity_H group). The abundances of immune cells were higher in the Immunity_H group, which indicated a better prognosis. Through further statistical analysis, we identified four genes which were highly correlated with prognosis and representative of this gene set, namely ARL4C, SERPINE1, BST2, and AXIN2. When the patients were divided into low- and high-risk groups based on their risk scores, we found that patients in the high-risk group had shorter overall survival time. Moreover, a nomogram including clinicopathologic features and the established risk signature could robustly predict 1-, 3-, and 5-year survival in patients with colon cancer.Conclusion: We identified two distinct immune patterns by analyzing clinical and transcriptomic information from colon cancer patients. A subsequently constructed immune-related gene-based prognostic model as well as a nomogram model can be used to predict the prognosis of colon cancer, thereby guiding risk stratification and treatment regimen development for colon patients.
Pb2+ Responsive Cu-In-Zn-S Quantum Dots With Low Cytotoxicity
Authors: Han XiaoLe , Yu Fan , Lei JiaWen , Zhu Jiahua , Fu HaiYan , Hu JunCheng , Yang Xiao-Long 
Published: February 2022

Water-soluble Cu-In-Zn-S quantum dots (CIZS QDs) with orange fluorescence have been synthesized with a glutathione (GSH) as stabilizer via facile a one-step hydrothermal method. The optimal reaction conditions of CIZS QDs including temperature, time, pH, and the molar ratios of precursors were studied. TEM results indicate that the aqueous-dispersible CIZS QDs are quasi-spherical, and the average diameters are 3.76 nm with excellent fluorescent stability. Furthermore, the cytotoxicity of CIZS QDs was investigated by the microcalorimetry combining with TEM and the IC50 was 10.2 μM. CIZS QDs showed a promising perspective in applications such as a fluorescent probe for bioimaging and biolabeling due to the low cytotoxicity and good biocompatibility. Moreover, the CIZS QDs can distinguish Pb2+ ion from other ions, offering great potentials in lead ion determination in drinking water. According to the results of UV, XRD, FL, PL, and ITC methods, the mechanism of CIZS QDs-Pb2+ assay is due to hydrogen bonding or van der Waals forces in the formation of Pb2+ and CIZS QDs.
Visual Search in Naturalistic Scenes Reveals Impaired Cognitive Processing Speed in Multiple Sclerosis
Authors: Gehrig Johannes , Bergmann Heinrich Johannes , Fadai Laura , Soydaş Dilara , Buschenlange Christian , Naumer Marcus J. , Kaiser Jochen , Frisch Stefan , Behrens Marion , Foerch Christian , Yalachkov Yavor 
Published: February 2022

BackgroundStandardized neuropsychological testing serves to quantify cognitive impairment in multiple sclerosis (MS) patients. However, the exact mechanism underlying the translation of cognitive dysfunction into difficulties in everyday tasks has remained unclear. To answer this question, we tested if MS patients with intact vs. impaired information processing speed measured by the Symbol Digit Modalities Test (SDMT) differ in their visual search behavior during ecologically valid tasks reflecting everyday activities.MethodsForty-three patients with relapsing-remitting MS enrolled in an eye-tracking experiment consisting of a visual search task with naturalistic images. Patients were grouped into “impaired” and “unimpaired” according to their SDMT performance. Reaction time, accuracy and eye-tracking parameters were measured.ResultsThe groups did not differ regarding age, gender, and visual acuity. Patients with impaired SDMT (cut-off SDMT-z-score &lt; −1.5) performance needed more time to find and fixate the target (q = 0.006). They spent less time fixating the target (q = 0.042). Impaired patients had slower reaction times and were less accurate (both q = 0.0495) even after controlling for patients' upper extremity function. Exploratory analysis revealed that unimpaired patients had higher accuracy than impaired patients particularly when the announced target was in unexpected location (p = 0.037). Correlational analysis suggested that SDMT performance is inversely linked to the time to first fixation of the target only if the announced target was in its expected location (r = −0.498, p = 0.003 vs. r = −0.212, p = 0.229).ConclusionDysfunctional visual search behavior may be one of the mechanisms translating cognitive deficits into difficulties in everyday tasks in MS patients. Our results suggest that cognitively impaired patients search their visual environment less efficiently and this is particularly evident when top-down processes have to be employed.
The Impact and Clinical Prediction of Hyperglycemia During Parenteral Nutrition for Nondiabetic Patients After Gastrectomy for Gastric Cancer
Authors: Lan Ning , Chen Xiaohua , Lu Ying , Zhou Yujie , Kong Fei , Zhao Yining , Jiao Fuzhi , Zhang Lin , Yuan Wenzhen 
Published: February 2022

Background and PurposeHyperglycemia (HG) is associated with increased postoperative complications. This study aims to evaluate the effect of HG during supplemental parenteral nutrition (SPN) on short-term prognosis in non-diabetic patients undergoing gastrectomy for cancer and to analyse the risk factors and prevention methods for HG.MethodsA total of 359 patients were divided into three groups according to blood glucose (BG) during SPN: normoglycemic patients ( ≤ 125 mg/dL), mild HG (125~200 mg/dL), and severe HG (&gt;200 mg/dL). The effect of BG on postoperative short-term outcomes was analyzed. Multivariate regression was performed to investigate influencing factors for severe HG. The safety and efficacy of insulin addition to total nutrient admixture (TNA) for the prevention and management of HG were assessed by propensity score matching (PSM). In addition, regression analysis was performed in the noninsulin group to investigate the predictive factors of severe HG, and a nomogram was plotted.ResultsThe postoperative complication rate was 18.9%, but it was significantly higher in patients with severe HG than in mild HG and normoglycemic patients (25.2, 15.0, and 10.0%, respectively, p &lt; 0.05). Multivariate logistic regression analysis showed that anemia, myosteatosis, higher postoperative capillary blood glucose (CBG) before TNA infusion, and insulin in the TNA were independent influencing factors for severe HG. Based on the above factors, 75 pairs of patients (insulin group and non-insulin group) with comparable baseline data were successfully matched by PSM. The HG incidence and the glycemic fluctuation were significantly improved through 1 U insulin/6 g glucose (1/6 scheme) to TNA. A nomogram containing hemoglobin, skeletal muscle radiodensity, pre-SPN CBG, and pTNM stage with good predictive efficacy (C-index: 0.750) was constructed based on the noninsulin group.ConclusionPoor postoperative glycemic control was related to worse outcomes in non-diabetic patients undergoing gastrectomy for cancer. Pre-operative anemia, myosteatosis, and high postoperative CBG before TNA infusion are risk factors for severe HG. Insulin in TNA can improve the blood glucose control of patients. Our proposed nomogram rendered an individualized predictive tool for HG during SPN, which helps screen high-risk patients requiring insulin therapy. Future studies with larger samples are needed to develop a complete insulin application protocol for SPN.
SP1-Mediated Upregulation of circFAM126A Promotes Proliferation and Epithelial-Mesenchymal Transition of Oral Squamous Cell Carcinoma via Regulation of RAB41
Authors: Wang Jun , Ouyang Shaobo , Zhao Siyu , Zhang Xianhua , Cheng Mingyang , Fan Xin , Cai Ying , Liao Lan 
Published: February 2022

BackgroundAccumulating evidence indicates that circular RNAs have major roles in the progression of human cancers. Nevertheless, the molecular mechanism and effects of circFAM126A in oral squamous cell carcinoma (OSCC) remain unclear.MethodsQuantitative real-time PCR (qRT-PCR) was used to detect expression levels of circFAM126A in OSCC tumor tissues and cell lines; the effects of circFAM126A small hairpin RNA (shRNA) on the proliferation, migration, and invasion of OSCC cells were detected by MTT, colony formation, and transwell assays; xenograft mouse models were used to determine the effects of circFAM126A shRNA on the growth of OSCC tumors in vivo; the expression of miR-186 and RAB41 in OSCC tissues and cells was examined by qRT-PCR; the targeting relationship between circFAM126A and miR-186 was verified by dual-luciferase reporter and RNA pull-down assays; and the relationship between miR-186 and RAB41 was explored.ResultsThe expression of circFAM126A was significantly upregulated in OSCC tissues and cells. The transcription factor SP1 transcriptionally activated circFAM126A. However, knockdown of circFAM126A markedly suppressed the proliferation, migration, and invasion of OSCC cells in vitro and inhibited tumor growth and distant metastasis in vivo. Moreover, circFAM126A increased the expression of RAB41 and promoted its mRNA stability via binding to miR-186 and RNA-binding protein FUS. Overexpression of RAB41 antagonized the effects of circFAM126A knockdown and induced an aggressive phenotype of OSCC cells.ConclusionSP1 transcriptionally activated circFAM126A modulated the growth, epithelial-mesenchymal transition (EMT) of OSCC cells via targeting the miR-186/FUS/RAB41 axis, suggesting that circFAM126A is a potential biomarker for the treatment of OSCC.
Characterizing Esophageal Motility in Neonatal Intensive Care Unit Patients Using High Resolution Manometry
Authors: Rayyan Maissa , Omari Taher , Cossey Veerle , Allegaert Karel , Rommel Nathalie 
Published: February 2022

ObjectiveTo characterize esophageal motility and esophago-gastric junction (EGJ) function during feeding in neonatal intensive care unit (NICU) patients.Patients and MethodsHigh resolution manometry with impedance (HRIM) was used to investigate esophageal motility and EGJ function in patients admitted to the NICU. Twenty-eight preterm born infants with bronchopulmonary dysplasia (BPD), 12 born with isolated congenital diaphragmatic hernia (iCDH), and 10 with esophageal atresia (EA) were included. Thirteen healthy infants were included as controls. Esophageal motility and EGJ function were analyzed using objective esophageal bolus transport parameters.ResultsNormal esophageal peristaltic wave patterns were observed in all investigated infants without EA. Nine of 10 patients with EA presented with abnormal esophageal motor wave patterns. A total of 224 nutritive swallows were analyzed (controls, n = 48; BPD, n = 96; iCDH, n = 60; EA, n = 20). Infants with BPD and iCDH had similar distal contractile strength (DCI) compared to healthy controls, while in patients with EA, DCI was significantly lower (Kruskal-Wallis test, p = 0.001). In most infants, EGJ relaxation after swallowing was unaffected. EGJ barrier function, in terms of EGJ-contractile integral, also appeared well-developed and did not differ significantly among patient groups.ConclusionsWe conclude that esophageal motility studies using pressure-impedance analysis are feasible in young infants. Bolus transport mechanisms following nutritive swallows appeared well-established in all investigated infants with the exception of those with EA. EGJ relaxation was also functional after deglutition and EGJ function as an anti-reflux barrier appeared well-developed in all investigated NICU groups.
Alarming Increase of Ketoacidosis Prevalence at Type 1 Diabetes-Onset in Austria—Results From a Nationwide Registry
Authors: Nagl Katrin , Waldhör Thomas , Hofer Sabine E. , Fritsch Maria , Meraner Dagmar , Prchla Christine , Rami-Merhar Birgit , Fröhlich-Reiterer Elke 
Published: February 2022

ObjectiveWe analyzed the annual prevalence of onset-DKA (diabetic ketoacidosis) from 2012 to 2020 with a sub-analysis for lockdown-periods during the COVID-19 pandemic in 2020.DesignAll newly diagnosed children with type 1 diabetes (T1D) aged &lt;15 years are prospectively registered in the population-based Austrian Diabetes Incidence Study in Austria.Main Outcome MeasuresThe annual DKA prevalence was analyzed using Joinpoint regression. Definition of DKA: pH &lt;7.3, mild DKA: pH 7.3 to ≤ 7.1, severe DKA: pH &lt;7.1. DKA prevalence during the lockdown periods in 2020 and the corresponding periods in 2015–2019 were examined using Fisher's exact test.ResultsIn the years 2012–2020 the mean prevalence for onset-DKA in Austria was 43.6% [95%CI (confidence interval): 41.6, 45.7] and thus above the mean prevalence of previous decades (1989–2011) of 37,1 % (95%CI: 35.6, 38.6). A particularly high prevalence was found among children &lt;2 years of age (72.0% DKA, 32.8% severe DKA). No significant gender difference was found. Prevalence of severe DKA at T1D-onset increased significantly since 2015 (p = 0.023). During the lockdown in 2020, 59.3% of children were diagnosed with DKA at T1D-onset, compared to 42.1% during the previous 5 years (p = 0.022). Moreover, 20% of children had severe DKA at T1D diagnosis, compared to 14% during the comparison period.ConclusionsThe previously already high prevalence of DKA at T1D-onset has further increased over time. The COVID-19 pandemic has exacerbated the problem of a late or delayed diagnosis of diabetes in children resulting in onset-DKA. The alarmingly increased prevalence of DKA in Austrian children with T1D calls for urgent action.