bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evolution of the French Guiana coast from Late Pleistocene to Holocene based on chenier and beach sand dating
Authors: Brunier Guillaume , Tamura Toru , Anthony Edward J. , Dussouillez Philippe , Gardel Antoine 
Published: October 2022

Abstract The 1500-km-long Guianas coast between the Amazon delta in Brazil and the Orinoco delta in Venezuela is characterized by alternations of muddy shoreline advance and retreat caused by large mud banks migrating alongshore from the mouths of the Amazon. In this dominantly muddy environment, wave reworking of sand and shells results in the formation of beaches, termed ‘cheniers’, that provide valuable information on coastal evolution, especially on past erosional phases. Twenty-eight depositional ages showing the long-term patterns of shoreline mobility in French Guiana were obtained from optically stimulated luminescence. Twenty-one ages younger than 7 ka define three clusters centred on 4.5 ka, 1.0–1.3 ka, and 0.30 ka. They indicate that chenier formation was relatively synchronous and significantly affected by alongshore diversions of river mouths and changes in river-mouth position over time under the influence of muddy shoreline advance. A prominent cluster at 1.0–1.3 ka reveals a clear hiatus after the 4.5 ka cluster, indicating that the present muddy coastal plain of French Guiana was largely formed and preserved after 1.0–1.3 ka. This cluster also implies either an episode of coastal retreat or no coastal advance around 1.0–1.3 ka. The remaining seven samples were derived from Late Pleistocene deposits of headland-bound beaches and probable cheniers capped by aeolian sand, suggesting similar conditions of coastal Amazon mud-dominated sedimentation. By informing on past patterns of shoreline mobility, these results have broader implications for coastal land-use planning and shoreline management between the mouths of the Amazon and Orinoco Rivers.
Predictive factors for functional failure of ventral mesh rectopexy in the treatment of rectal prolapse and obstructed defecation
Authors: Solari S. , Martellucci J. , Ascanelli S. , Sturiale A. , Annicchiarico A. , Fabiani B. , Prosperi P. , Carcoforo P. , Naldini G. 
Published: October 2022

Abstract
Background
Ventral mesh rectopexy (VMR) is widely accepted for the treatment of rectal prolapse or obstructed defecation. However, despite good anatomical results, the improvement of functional symptoms (constipation or incontinence) cannot always be obtained and in some cases these symptoms may even worsen. The aim of the present study was to identify possible predictors of functional failure after VMR.

Methods
Data of all consecutive patients who had VMR for the treatment of rectal prolapse and/or obstructed defecation between January 2017 and December 2020 in three different pelvic floor surgical centres in Italy were analysed to identify possible predictors of functional failure, intended as persistence, worsening or new onset of constipation or faecal incontinence. Symptom severity was assessed pre- and postoperatively with the Wexner Constipation score and Obstructed Defecation Syndrome score. Quality of life was assessed, also before and after treatment, with the Patients Assessment of Constipation Quality of Life questionnaire, the Pelvic Floor Disability Index and the Pelvic Floor Impact Questionnaire. Faecal incontinence was evaluated with the Cleveland Clinic Incontinence Score. The functional outcomes before and after surgery were compared.

Results
Sixty-one patients were included (M:F ratio 3:60, median age 64 years [range 33–88 years]). Forty-two patients (68.9%) had obstructed defecation syndrome, 12(19.7%) had faecal incontinence and 7 patients (11.5%) had both. A statistically significant reduction between pre- and postoperative Obstructed Defecation Syndrome and Wexner scores was reported (p < 0.0001 in both cases). However, the postoperative presence of constipation occurred in 22 patients (36.1%) (this included 3 cases of new-onset constipation). The presence of redundant colon and the pre-existent constipation were associated with an increased risk of persistence of constipation postoperatively or new-onset constipation (p = 0.004 and p < 0.0001, respectively). The use of postoperative pelvic floor rehabilitation (p = 0.034) may reduce the risk of postoperative constipation.

Conclusions
VMR is a safe and effective intervention for correcting the anatomical defect of rectal prolapse. The degree of prolapse, the presence of dolichocolon and pre-existing constipation are risk factors for the persistence or new onset of postoperative constipation. Postoperative rehabilitation treatment may reduce this risk.
How to evaluate and assess the epileptogenic/seizure potential of periodic discharges along the ictal-interictal continuum?
Authors: Gélisse Philippe , Kaplan Peter W. 
Published: October 2022

AbstractThe ictal–interictal continuum (IIC) is a concept used for those particular EEG patterns that do not meet the strict criteria for status epilepticus but may be associated with neuronal injury. The aim of this article is to review equivocal periodic patterns and to discuss their clinical significance along the IIC. The risk of seizures increases when the frequency of periodic discharges exceeds 2 Hz and when the pattern has features of superimposed rhythmic, sharp, or fast activity (plus modifier). Lateralized periodic discharges (LPDs) are one of the best examples of the IIC. Criteria have been proposed for identifying patterns along the IIC that we called “peri-ictal” LPDs. There is ongoing debate about when to treat patients with these EEG patterns along this spectrum. The term IIC is only an EEG description, and does not in itself reflect a clinical diagnosis, hence management is based on EEG alone. The decision to intensify treatment is based on the combination of EEG, the underlying etiology, the level of consciousness, comorbidities, imaging, and other surrogates of “damage.”
The scope of food fraud revisited
Authors: Gussow K. E. , Mariët A. 
Published: October 2022

AbstractFood fraud is an emerging field of study in academic literature. The aim of this paper is to evaluate whether current understanding of food fraud in literature is in congruence with incidents of food fraud in the Netherlands. The discussion that follows is based on an analysis of 53 empirical cases on food fraud investigations conducted at the Netherlands Food and Consumer Product Safety Authority (NVWA), the nationwide enforcement body tasked with investigating food fraud. The findings elucidate the differences between food fraud and other (food) crime and highlight the discrepancies with academic definitions to date, most notably with respect to incidents of ‘food laundering’ and by emphasizing the existence of intentional facilitators. We thus suggest adjusting the scope of what type of behavior can be considered as food fraud by conceptualizing three forms of food fraud: food laundering, fraudulent food enhancement, and facilitative food fraud. Food laundering encompasses the use of illegal material as food, whereas fraudulent food enhancement describes a situation where legal food is value-enhanced through deceitful cost-cutting measures. Facilitative food fraud captures the role of facilitative actors that operate illegally and intentionally for economic advantage. Based on these concepts, we suggest a modified definition as follows: food fraud is committed by any actor who is intentionally involved in illegal acts for economic advantage, thus causing or facilitating illegal food to be laundered into the supply chain or for food to be fraudulently value-enhanced. Future research should focus on testing these concepts and this definition with empirical studies from different regions and regulatory settings, and introduce additional data sources outside of enforcement, such as employee or victim surveys.
Practical joint human-machine exploration of industrial time series using the matrix profile
Authors: Nilsson Felix , Bouguelia Mohamed-Rafik , Rögnvaldsson Thorsteinn 
Published: October 2022

AbstractTechnological advancements and widespread adaptation of new technology in industry have made industrial time series data more available than ever before. With this development grows the need for versatile methods for mining industrial time series data. This paper introduces a practical approach for joint human-machine exploration of industrial time series data using the Matrix Profile, and presents some challenges involved. The approach is demonstrated on three real-life industrial data sets to show how it enables the user to quickly extract semantic information, detect cycles, find deviating patterns, and gain a deeper understanding of the time series. A benchmark test is also presented on ECG (electrocardiogram) data, showing that the approach works well in comparison to previously suggested methods for extracting relevant time series motifs.
Making sense of change in higher education research: exploring the intersection of science and policy
Authors: Brankovic Jelena , Cantwell Brendan 
Published: October 2022

AbstractHigher education studies give considerable attention to understanding change. The interest in change reflects the historical conditions in which higher education emerged as a distinct field of study. Around the mid-twentieth century, a pragmatic need for an academic response to managing larger and more complex higher education institutions and systems was taking shape. This need gave rise to a tradition of studying change in higher education, which has continued into the present. To explore how higher education researchers have been grappling with the problem of change, we examine a selection of works published in this and other higher education outlets since the 1970s. We organize our exploration around three distinct yet interrelated lines of research: (a) change within higher education institutions, which in higher education studies are typically conceptualized as organizations; (b) change concerning nation-states, which are usually conceptualized as systems; and (c) transnational change, sometimes referred to also as global. Each line of research features the field’s telltale dual orientation: (i) contributing to abstract knowledge through academic inquiry, on the one hand, and (ii) generating practical and actionable insights for decision makers, on the other. We find that the field’s dual orientation shapes knowledge creation along each line of inquiry, yet with important variations. We propose more generally that higher education studies’ ability to balance the two orientations is an important source of its legitimacy as a field of research.
A model-based cost-effectiveness analysis of fracture liaison services in China
Authors: Li Nannan , Si Lei , Boonen Annelies , van den Bergh Joop P. , Hiligsmann Mickaël 
Published: October 2022

Abstract

Summary

This study is a model-based cost-effectiveness analysis of fracture liaison services (FLS) in China, suggesting that FLS could potentially lead to lifetime cost-saving in patients who have experienced a fracture. However, Chinese-specific real-world data is needed to confirm the results of our study.

Purpose
The study aimed to assess the potential cost-effectiveness of fracture liaison services (FLS) from the Chinese healthcare perspective with a lifetime horizon.

Methods
A previously validated Markov microsimulation model was adapted to estimate the cost-effectiveness of FLS compared to no-FLS. The evaluation was conducted in patients aged 65 years with a recent fracture. Treatment pathways were differentiated by gender, FLS attendance, osteoporosis diagnosis, treatment initiation, and adherence. Given the uncertainty in FLS cost, the cost in the base-case analysis was assumed at US$200. Analyses were also performed to determine the maximum cost for making the FLS cost-saving and cost-effective at the Chinese willingness-to-pay (WTP) threshold. One-way sensitivity analyses were conducted.

Results
When compared with no-FLS, the FLS was dominant (lower costs, higher quality-adjusted life years) in our target population at the FLS cost of US$200 per patient. For every 100 patients who were admitted to the FLS, approximately four hip fractures, nine clinical vertebral fractures, and three wrist fractures would be avoided over their lifetimes. Our findings were robust to numerous one-way sensitivity analyses; however, the FLS was not cost-effective in patients aged 80 years and older.

Conclusion
FLS could potentially lead to lifetime cost-saving in patients who have experienced a fracture. Our study informs the potential cost-effectiveness of FLS and the knowledge gap in China; more future research incorporating Chinese-specific real-world data are needed to confirm the results of our study and to better evaluate the cost-effectiveness of FLS in China.
COMPAS: zu einer wegweisenden Debatte über algorithmische Risikobeurteilung
Authors: Räz Tim 
Published: October 2022

Zusammenfassung„Correctional Offender Management Profiling for Alternative Sanctions“ (COMPAS) ist ein Risikobeurteilungsinstrument, das im Bereich der Strafjustiz in den USA eingesetzt wird. An COMPAS hat sich eine lebhafte Diskussion über Fairness entzündet, die bis heute andauert. Jedoch wurde diese Diskussion im deutschsprachigen Kontext bisher nicht stark rezipiert. In diesem Beitrag wird zuerst die Risikobeurteilung durch COMPAS systematisch dargestellt und diskutiert, wie COMPAS in den USA eingesetzt wird. Es wird dann auf drei wichtige Aspekte der Diskussion über COMPAS eingegangen, nämlich Fairness, Transparenz und Daten. Schließlich wird angedacht, welche Konsequenzen man aus der Diskussion für den deutschsprachigen Kontext ziehen kann.
Assessment of personal deposited dose of bioaerosols and particles in a wastewater treatment plant facility
Authors: Chalvatzaki Eleftheria , Katsivela Eleftheria , Raisi Louiza , Lazaridis Mihalis 
Published: October 2022

AbstractThe daily deposited dose of bioaerosols and particle mass or number in the human respiratory tract using an exposure dose model (ExDoM2) was quantified in the present study. The dose was calculated for the extrathoracic (ET), tracheobronchial (TB), and alveolar-interstitial (AI) regions of the human respiratory tract. The calculations were performed for viable, cultivable airborne heterotrophic bacteria, mesophilic fast-growing fungi, and total coliforms at a municipal wastewater treatment plant (WWTP) located at a suburban area at a Mediterranean site. The human dose was determined using data from two locations at the WWTP which correspond to two different wastewater treatment stages (aerated grit chamber (indoor) and primary settling tanks (outdoor)) and one outdoor location at the urban background site. In addition, the model simulations were performed for two exposure periods (March to April and May to June 2008). Higher daily deposited dose in the total human respiratory tract was observed for heterotrophic bacteria at the aerated grit chamber, whereas lower values of heterotrophic bacteria were observed at the primary settling tanks. These findings were associated with the corresponding stage of wastewater treatment activities and may be valuable information for determining future dose–response relationships. In addition, higher daily deposited dose was determined in the ET region for the three categories of bioaerosols. Regarding PM10 and PN1, the higher daily deposited dose received by a worker at the aerated grit chamber. Finally, the hazard quotients were estimated and the results showed that the non-carcinogenic effects can be ignored for bioaerosols and PM10 except for workers present at aerated grit chamber. Regarding PM2.5, the non-carcinogenic effects are of concern and cannot be ignored for all cases.
Rho-associated kinase1 promotes laryngeal squamous cell carcinoma tumorigenesis and progression via the FAK signaling pathway
Authors: Yang Liyun , Qiao Peipei , Zhang Jianwei , Huang Shuixian , Hu An 
Published: October 2022

AbstractLaryngeal squamous cell carcinoma (LSCC) is one of the most common head and neck squamous cell carcinomas (HNSCC). Rho-associated kinase1 (ROCK1) is considered to promote progression of numerous cancers, however, its role in LSCC is still unknown. Here, the expression level of ROCK1 is higher in LSCC tissues than non-tumor tissues, and the expression level of ROCK1 is positively correlated with advanced stage and poor survival prognosis. ROCK1 knockdown in TU686 and TU212 cells dramatically inhibits cellular proliferation, migration and invasion. Whereas the overexpression of ROCK1 reversed these changes. FAK signaling pathway plays an essential role in promoting LSCC progression. Inhibiting FAK activity with TAE226 observably impairs the tumor-promoting effects. In conclusion, ROCK1 promotes LSCC tumorigenesis and progression via the FAK signaling pathway, targeting the ROCK1 molecule may represent potential targets for clinical LSCC treatment.
On the RO(Q)-graded coefficients of Eilenberg–MacLane spectra
Authors: Sikora Igor 
Published: October 2022

AbstractLet Q denote the cyclic group of order two. Using the Tate diagram we compute the RO(Q)-graded coefficients of Eilenberg–MacLane Q-spectra and describe their structure as modules over the coefficients of the Eilenberg–MacLane spectrum of the Burnside Mackey functor. If the underlying Mackey functor is a Green functor, we also obtain the multiplicative structure on the RO(Q)-graded coefficients.
Norwegian Cross-Cultural Adaptation of the Social and Communities Opportunities Profile-Mini for Persons with Concurrent Mental Health and Substance Use Disorders
Authors: Leonhardt Marja , Kyrdalen Ellen , Holstad Atle , Hurlen-Solbakken Heidi , Chiu Marcus Yu-Lung , Lien Lars 
Published: October 2022

AbstractPersons with concurrent mental health and substance use disorders often do not participate actively in society and remain marginalized. The promotion of social inclusion is important for the care of persons with concurrent disorders. To measure social inclusion, the Social and Communities Opportunities Profile (SCOPE) was developed, followed by its mini version for English-speaking people in Singapore. In Norway, there is no instrument available to measure social inclusion. Thus, the aim was cross-cultural adaptation of SCOPE Mini for persons with concurrent disorders. The Norwegian adaptation was performed using the systematic approach recommended by Beaton et al. After a forward–backward translation, the Norwegian SCOPE-Mini was pre-tested among 30 persons with a concurrent mental health and substance use disorder in three areas to check its psychometric properties. To evaluate comprehensibility and applicability, participants were asked five open questions. The Norwegian cross-cultural adaptation of SCOPE Mini showed acceptable psychometric properties and was considered comparable to the original version. The results of the pre-test showed no linguistic inconsistency, but some indications of the necessity of semantic adaptation regarding the cultural context and persons with concurrent disorders. The Norwegian SCOPE Mini may be a practical tool for health professionals, social workers, and researchers to measure social inclusion among a vulnerable group such as persons with a concurrent mental health and substance use disorder. However, given the relatively small sample size in our study, further research on the validity and reliability of the instrument is recommended.
Iitaka fibrations for dlt pairs polarized by a nef and log big divisor
Authors: Hashizume Kenta 
Published: October 2022

AbstractWe study lc pairs polarized by a nef and log big divisor. After proving the minimal model theory for projective lc pairs polarized by a nef and log big divisor, we prove the effectivity of the Iitaka fibrations and some boundedness results for dlt pairs polarized by a nef and log big divisor.
Indigena Self-Identity in Ecuador and The Rejection of Mestizaje
Authors: Beck Scott H. , Mijeski Kenneth J. 
Published: October 2022

AbstractIndigenous peoples of Ecuador have organized and mobilized over the past thirty years, partly to reshape their identities after centuries of domination. This research is a preliminary effort to explore the contemporary complexity of that identity. Best viewed as a quantitative case study, this analysis uses responses from seventy-six indigenous college students to a self-administered questionnaire. The authors found that indigenous students with greater “acculturation experiences” with mestizo culture were more strident in rejecting elements of that culture than were their colleagues who had had fewer encounters with mestizo elements of Ecuadorian society. While the tendency to identify oneself ethnically by rejecting the dominant culture represents only one dimension of ethnic identity (maintaining distinctiveness), the authors consider the findings important for future research on the dynamics of the process of ethnic identification.
Latin American Materials in the Comintern Archive
Authors: Ching Erik , Pakkasvirta Jussi 
Published: October 2022

AbstractWith the collapse of the Soviet Union, restrictions on archives in Russia have diminished markedly. Some of the repositories have potential interest for Latin Americanists, including the Comintern Archive. This research note discusses the objectives of the archive and the types of material it contains. A list of the major collections relevant to Latin America is followed by comments on how to use the archive and websites that will facilitate research in Russia. Also provided are bibliographic references to academic studies on Latin America based on Comintern materials.
Income Distribution and Environmental Degradation in the Argentine Interior
Authors: Sawers Larry 
Published: October 2022

AbstractThis article analyzes the environmental degradation of the Argentine interior, emphasizing the roles played by different income groups. Argentina beyond the pampa is composed of fragile ecosystems that have been substantially degraded through decades or even centuries of overuse and abuse. This study ascertains the nature and extent of environmental degradation for each part of the interior, the relative importance of various income groups in agricultural production, and the differential tendency to degrade the environment of agriculturalists at different income levels. These variables are used to show that both the wealthy and the poor have played crucial roles in the environmental degradation of the Argentine interior.
Periodicos y Formacion Nacional: Bolivia en sus primeros años
Authors: Unzueta Fernando 
Published: October 2022

ResumenEste artículo examina el papel constitutivo de los periódicos bolivianos en los inicios del proceso deformación nacional (1825–1855, aproximadamente). Discute su intervención en los debates políticos y legales del momento, sus esfuerzos por definir los elementos que identifican con la nacionalidad, su inserción en un precario mercado, su promoción de los valores patrios y participación en la formación de ciudadanos. El artículo muestra la capacidad incorporadora de elementos heterogéneos que tienen las hojas impresas y, sobre todo, la reconceptualización del tiempo y el espacio que articulan en términos de lo nacional. Finalmente, sin minimizar las contribuciones del proyecto letrado de construcción nacional, destaca también las tensiones y limitaciones que le son inherentes.