bluuebunny/crossref_metadata_2025_split huggingface dataset:
IL-22/IL-22RA1 promotes human Tenon’s capsule fibroblasts proliferation and regulates fibrosis through STAT3 signaling pathway
Authors: Zhao Yang , Zhou Xiaoyu , Zhang Xinyue , Zhou Dengming , Chen Baihua , Duan Xuanchu 
Published: August 2022

AbstractThe study is aimed to investigate that the IL-22/IL-22RA1 signaling pathway regulates scar formation. A total of 31 glaucoma patients who had been previously treated with trabeculectomy surgery and the intraocular pressure was uncontrollable because of scarring and 19 strabismus patients as control patient group. ELISA showed that the IL-22 content of serum from glaucoma patients was 29.80±5.1 ng/μl which is higher than that 5.21±0.9 ng/μl from healthy group significantly. Serum from patients was used to incubate human Tenon’s capsule fibroblasts (HTFs) cells and IL-22 antibody rescued the effect of IL-22 on the biological functions. qPCR and western blot result showed that IL-22 mediates the biological function of HTFs cells via binding IL-22RA1 directly. When transfection of siR-IL-22RA1 or IL-22RA1 gene, the HTFs cells shown significantly anti-fibrosis or pro-fibrosis separately. By using STAT3 inhibitor BAY in IL-22RA1 overexpression group, IL-22-induced proliferation were reduced in HTFS cells. IL-22 promoted fibroblasts cell proliferation and α-SMA via IL-22/IL-22RA1/STAT3 signaling pathway, thereby potentially regulating glaucoma filtration trace fibrosis. This results also show the novel factor in process of postoperative scarring.Summary StatementThe present study suggested that IL-22 expression in glaucoma patient after surgery. IL-22/IL-22RA1 signaling pathway promoted fibroblasts cell proliferation and α-SMA by activating the STAT3 signaling pathway, thereby potentially regulating glaucoma filtration trace fibrosis.
Understanding relationship between topic selection and academic performance of scientific teams based on entity popularity trend
Authors: Zhang Tongyang , Tan Fang , Yu Chao , Wu Jiexun , Xu Jian 
Published: August 2022

PurposeProper topic selection is an essential prerequisite for the success of research. To study this, this article proposes an important concerned factor of topic selection-topic popularity, to examine the relationship between topic selection and team performance.Design/methodology/approachThe authors adopt extracted entities on the type of gene/protein, which are used as proxies as topics, to keep track of the development of topic popularity. The decision tree model is used to classify the ascending phase and descending phase of entity popularity based on the temporal trend of entity occurrence frequency. Through comparing various dimensions of team performance – academic performance, research funding, relationship between performance and funding and corresponding author's influence at different phases of topic popularity – the relationship between the selected phase of topic popularity and academic performance of research teams can be explored.FindingsFirst, topic popularity can impact team performance in the academic productivity and their research work's academic influence. Second, topic popularity can affect the quantity and amount of research funding received by teams. Third, topic popularity can impact the promotion effect of funding on team performance. Fourth, topic popularity can impact the influence of the corresponding author on team performance.Originality/valueThis is a new attempt to conduct team-oriented analysis on the relationship between topic selection and academic performance. Through understanding relationships amongst topic popularity, team performance and research funding, the study would be valuable for researchers and policy makers to conduct reasonable decision making on topic selection.
Reasons for resistance to e-waste recycling: evidence from an emerging economy
Authors: Sajid Muhammed , Zakkariya K.A. 
Published: August 2022

PurposeThe purpose of this paper, an empirical research, is to identify the psychological and functional barriers that result in e-waste recycling resistance.Design/methodology/approachThe study is equipped with the theoretical lens of the innovation resistance theory. Households living in an Indian city were surveyed using a pre-validated questionnaire. Statistical analysis for the study was done with partial least squares – structural equation modeling.FindingsThe outcome of the survey exhibited that the significant factors contributing to e-waste recycling resistance are usage barrier, value barrier, risk barrier and tradition barrier.Practical implicationsThe study offers implications for multiple stakeholders, which aid them in formulating strategies to overcome e-waste recycling resistance.Originality/valueThis research has remarkable importance as it is the pioneering study that extensively investigates the reasons for e-waste recycling resistance in an emerging economy. The study also empirically validates the moderating role of environmental awareness, age, gender and income in the relationship between barriers and resistance to e-waste recycling.
Joint board management meetings and earnings management
Authors: Agustia Dian , Harymawan Iman , Nasih Mohammad , Nowland John 
Published: August 2022

PurposeJoint board management meetings bring boards of directors and top management teams together to share information and discuss company matters. The authors investigate whether these joint meetings are associated with higher agency costs or information sharing benefits in the context of firm earnings management.Design/methodology/approachUsing publicly disclosed data on the frequency of joint board management meetings in Indonesian firms, the authors examine the relationship between joint board management meetings and earnings management during 2010–2017.FindingsThe authors find that more joint board management meetings are associated with lower earnings management. This is consistent with joint board management meetings providing net information sharing benefits. Additional testing indicates that the results are the strongest when firms hold more joint board management meetings than regular board meetings.Originality/valueThe findings suggest that in addition to holding regular board and audit committee meetings, formal meetings between boards of directors and top management teams are beneficial to shareholders by restricting opportunistic accounting choices by firm management.
Does green intellectual capital affect green innovation performance? Evidence from the Spanish wine industry
Authors: Marco-Lajara Bartolomé , Zaragoza-Sáez Patrocinio Carmen , Martínez-Falcó Javier , Sánchez-García Eduardo 
Published: August 2022

PurposeThe purpose of this study is to focus on analyzing how the set of green intangibles held by wineries and their members, i.e. green intellectual capital (GIC), affects green innovation performance (GIP). Specifically, the study aims to investigate how GIP is influenced by GIC through the mediating role of the variable knowledge management (KM) and corporate social responsibility (CSR).Design/methodology/approachThe study proposes a conceptual model, based on previous studies, which is tested through structural equations (PLS-SEM) with data collected from 202 Spanish wineries.FindingsThe results of the research indicate that there is a positive and significant relationship between GIC and GIP. Furthermore, CSR and KM partially mediate the relationship between these two variables, playing a key role in the environmental management of wineries.Originality/valueThe present research, therefore, contributes to the literature in several ways. First, the study advances the understanding of GIC as well as its link with GIP. Second, the research aims to fill the gap in the literature through the study of CSR and KM as mediating variables in such a link. Third, to the best of the authors’ knowledge, the model proposed has not been previously addressed in the academic literature, thus representing an advance in scientific knowledge. Fourthly, no research has addressed the study of environmental intangibles in the wine industry, with this research, therefore, being a pioneer in contextualizing the study of GIC in this increasingly knowledge-intensive industry.
Integrating knowledge management and BIM for safety risk identification of deep foundation pit construction
Authors: Chen Dawei , Zhou Jianliang , Duan Pinsheng , Zhang Jiaqi 
Published: August 2022

PurposeThe outbreak of COVID-19 pandemic has posed severe challenges to infrastructure construction in China. Particularly, the complex technology and high process uncertainty of deep foundation pit construction make its safety risk identification a challenging issue of general concern. To address these challenges, Building Information Modeling (BIM) can be used as an important tool to enhance communication and decision-making among stakeholders during the pandemic. The purpose of this study is to propose a knowledge management and BIM-integrated safety risk identification method for deep foundation pit construction to improve the management efficiency of project participants.Design/methodology/approachThis paper proposes a risk identification method that integrates BIM and knowledge management for deep foundation pit construction. In the framework of knowledge management, the topological relationships between objects in BIM are extracted and visualized in the form of knowledge mapping. After that, formal expressions of codes are established to realize the structured processing of specification provisions and special construction requirements. A comprehensive plug-in for deep foundation pit construction is designed based on the BIM software.FindingsThe proposed method was verified by taking a sub-project in deep foundation pit project construction as an example. The result showed the new method can make full use of the existing specification and special engineering requirements knowledge. In addition, the developed visual BIM plug-in proves the feasibility and applicability of the proposed method, which can help to increase the risk identification efficiency and refinement.Originality/valueThe deep foundation pit safety risk identification is challenged by the confusion of deep foundation pit construction safety knowledge and the complexity of the BIM model. By establishing the standardized expression of normative knowledge and special construction requirements, the efficiency and refinement of risk identification are improved while ensuring the comprehensiveness of results. Moreover, the topology-based risk identification method focuses on the project objects and their relations in the way of network, eliminating the problem of low efficiency from the direct BIM-based risk identification method due to massive data.
Much blame – little gain? The effects of single vs multi-blaming on labelling and third-party intervention in workplace bullying
Authors: Zedlacher Eva , Snowden Allison 
Published: August 2022

PurposeOrganizational practitioners must often interpret accounts of workplace bullying. However, they are frequently reluctant to confirm the target's account and often fail to set effective intervention measures. Building on novel approaches in attribution theory, this study explores how causal explanations and blame pattern shape the labelling of a complaint and the subsequent recommended intervention measures.Design/methodology/approach187 Austrian human resource professionals, employee representatives and other practitioners were confronted with a fictional workplace bullying complaint including conflicting actors' accounts and diverse possible internal, relational and external causes. Since the prior low performance of a target might affect blame attributions, the previous performance ratings of the target were manipulated. Data were analysed via qualitative content analysis.FindingsWhen respondents reject the complaint, they predominately identify single internal causes and blame the target, and/or trivialize the complaint as “normal conflict”. Both low and high performance of the target trigger (single) internal blame. When the complaint is supported, deontic statements and blame attributions against the perpetrator prevail; however, blame placed on the perpetrator is often discounted via multi-blame attributions towards supervisors, colleagues and the target. Structural causes were rarely mentioned. Relational attributions are infrequent and often used to trivialize the complaint. Irrespective of the attributional blame patterns, most third parties recommend “reconciliatory measures” (e.g. mediation) between the actors.Practical implicationsTrainings to temper single internal blaming and raise awareness of organizational intervention measures are essential.Originality/valueThis is the first study to investigate workplace bullying blaming patterns and organizational responses in detail.
The Palestinian health-care providers’ perceptions, challenges and human rights-related concerns during the COVID-19 pandemic
Authors: Mahamid Fayez Azez , Veronese Guido , Bdier Dana 
Published: August 2022

Purpose
One of the most affected groups during the COVID-19 pandemic was health-care providers due to the direct and continuous exposure to the virus and a lack of sufficient medical equipment. Palestinian health-care providers were exposed to several challenges related to their work environment as they worked in war-like conditions; therefore, this study aims to explore health-care providers’ perceptions, perspectives, challenges and human rights-related concerns during the COVID-19 Pandemic in Palestine.

Design/methodology/approach
The sample comprised 30 health-care providers 26–35 years, who were purposively selected from among health-care providers in two Palestinian cities, Nablus and Tulkarm, located in the north of the West Bank. Thematic content analysis was applied to transcripts of interviews with the practitioners to identify key themes.

Findings
The thematic content analysis showed that the pandemic and quarantine negatively affect the mental health outcomes, daily routine and social relations of health-care providers. The main challenges related to human rights violations and faced by the health-care providers include a lack of sufficient infrastructure, lack of medical equipment’s and protective gear, military occupation and a shortage of health-care providers in general, especially those who practice in speciality fields such as neurology, oncology, pediatric surgery and clinical psychology.

Practical implications
Further investigations are recommended to test different variables related to health-care providers’ work during the COVID-19 pandemic. This paper also recommends conducting studies targeting Palestinian health-care providers’ training and supervision services to improve their skills and resiliency in dealing with future crises.

Originality/value
The present work is the first to examine health-care providers’ perceptions, perspectives, challenges and human rights concerns during the COVID-19 pandemic in Palestine. This novel sample resides in a political and social environment characterized by high environmental stressors due to decades of military and political violence (e.g. militarization, poverty, lack of employment opportunities, cultural pressures, human rights violations, etc.)
Supply chain design for industrial additive manufacturing
Authors: Friedrich Anne , Lange Anne , Elbert Ralf 
Published: August 2022

PurposeThis study extends and refines the current knowledge on emerging supply chain designs (SCDs) for industrial additive manufacturing (AM) and manufacturing firms' rationales in selecting them.Design/methodology/approachFollowing an exploratory research design, a multiple-case study is conducted in the context of industrial AM. It focuses on two key dimensions of SCD, the geographic dispersion and governance structure. Four cohesive AM SCD configurations are characterized and form the basis for exploring the rationales for the SCD decision of manufacturing firms.FindingsThe findings indicate that manufacturing firms' SCD for industrial AM depends on the trade-off between economies of scale in a centralized setting and the market potential from customer proximity realized by decentral AM. Furthermore, the control of suppliers and the reevaluation of manufacturing firms' core competencies guide the governance choice. Many of the identified rationales currently drive manufacturing firms toward in-house AM at a centralized location or distributed AM in a secure, firm-owned network.Practical implicationsThe arguments for the AM SCD choices are illustrated. They provide guidance for managers of manufacturing firms when implementing industrial AM.Originality/valueThe study reveals and enhances the understanding of why the extant academic expectation of decentralized and outsourced AM is not sufficiently reflected in current industry practice. Thereby, the study provides a basis for elaborative decision-support research on AM SCDs.
Empowering resources recombination through dynamic capabilities of an enterprise
Authors: Muneeb Dilnaz , Ahmad Syed Zamberi , Abu Bakar Abdul Rahim , Tehseen Shehnaz 
Published: August 2022

PurposeThis study aims to provide insights on the importance of reconfiguring new and existing enterprise resources in a heterogeneous manner. This will lead to improved efficiencies, strategies and resource usage as such leading to more synergetic and innovative outcomes. This study highlights the importance of dynamic capabilities (DC) during the process of resources recombination (RR). It suggests that DC can be a source of competitive advantage, but the effect is contingent on the RR capabilities of enterprises.Design/methodology/approachData were obtained from 349 faculty members of higher education institutions (HEIs) from seven states in the United Arab Emirates (UAE). Partial least squares structural equation modeling (PLS-SEM) using SmartPLS was employed as a statistical tool to analyze the structural model.FindingsThe findings confirm the proposed role of DC in the realization of RR, in integrating and reconfiguring internal and external organizational skills and resources for efficiency and performance, since DC helps RR to reconfigure the resource base by extending, creating, and modifying innovative RRs.Practical implicationsThe study has important implications for resource managers and policymakers of HEIs. By prioritizing DC, firms can develop novel products and services as a result of a heterogenous mix of new RR. Additionally, since firms have limited resources in ever-changing, complex environmental conditions, this study provides explicit directions on how enterprises can strategically manage their resources in an innovative manner to attain a sustainable competitive advantage.Originality/valueInsights from the DC and RR perspective in HEI sectors, particularly in the Middle East region, are scarce. This is the first empirical study to delve in this area and exemplify the relationship between these significant constructs.
Identifying how the time on the market affects the selling price: a case study of residential properties in Paphos (Cyprus) urban area
Authors: Nikiforou Philippos , Dimopoulos Thomas , Sivitanides Petros 
Published: August 2022

PurposeThe purpose of this study is to investigate how the degree of overpricing (DOP) and other variables are associated with the time on the market (TOM) and the final selling price (SP) for residential properties in the Paphos urban area.Design/methodology/approachThe hedonic pricing model was used to examine the association of TOM and SP with various factors. The association of the independent variable of DOP and other independent variables with the two dependent variables of TOM and SP were investigated via ordinary least squares (OLS) regression models. In the first set of models the dependent variable was TOM and in the second set of models the dependent variable was SP. A sample of N = 538 completed transactions from Q1 2008 to Q2 2019 was used to estimate the optimum DOP that a seller must apply on the current market value of a property in order to achieve highest SP price in the shortest TOM.FindingsThe results of this study also suggest that the degree of overpricing in thin and less transparent markets is higher than that in transparent markets with high property transaction volumes. In mature markets like the USA and the UK where the actual sold prices are published, the DOP is around 1.5% which is much lower than the 11% DOP identified in this study.Practical implicationsIt was found that buyers are willing to pay more for the same house in a bigger plot than a bigger house in the same plot. The outcome is that smaller houses sell faster at a higher price per square meter than larger houses. Smaller houses are more affordable than larger houses.Social implicationsThere is a large pool of buyers for smaller houses than bigger houses. Higher demand for smaller houses results in a higher price per square meter for smaller houses than the price per square meter for bigger houses. Respectively the TOM for smaller houses is shorter than the TOM for bigger houses.Originality/valueThe database used is unique, from an estate agent located in Paphos that managed to sell more than 27,000 properties in 20 years. This data set is the most accurate information for Cyprus' property transactions.
Does the COVID-19 affect tenants’ adherence to lease obligations in rental market? Property managers’ perspective
Authors: Gbadegesin Job Taiwo 
Published: August 2022

PurposeThe purpose of this paper is to investigate how the pandemic affects tenants’ response to their lease obligations. This paper commences with examining the adopted tenant selection criteria during the COVID-19 pandemic. Then, this paper statistically tests if there is a relationship between selection criteria and response on whether the pandemic has effects or not. Then, this paper investigates the specific areas of impact on tenants’ ability to adequately keep to lease agreements in the Nigerian rental market. Finally, this paper proceeds to confirm if there is a relationship between selection criteria and the aspects of tenants’ deficiencies in rental obligations because of COVID-19.Design/methodology/approachSurvey data, backed with interviews, is elicited from practicing estate surveyors and valuers and licensed property managers in Lagos, the largest property market in Nigeria and sub-Sahara Africa. Policy solutions and implications were solicited from personnel at the ministry of housing and senior professionals in the property sector. Data were analyzed using descriptive statistics, factor analysis and computer-aided qualitative data analysis, Atlas.ti.FindingsTenant’s health status is now accorded a priority together with others. Numbers of tenants are challenged with keeping to the prompt-rent-payment rule. Other areas of slight breaches included livestock rearing, subletting, alteration and repair covenants. Except for tenant reputation and tenant family size, there was no significant relationship between tenant’s health status consideration and the COVID-19 effect on tenant non-compliance with lease obligation. Tenants’ non-compliance with tenancy obligations has a connection with the tenants’ affordability, reputation, ability to sign an undertaking and health conditions during the pandemic. This paper recommends rental housing policy review.Practical implicationsIt is recommended that the rental policy should be reviewed to give room for rental allowance or palliatives, private rental market regulation, exploration of the national housing fund and, if possible, social housing adoption policy in Nigeria.Originality/valueThis paper draws policymakers’ attention to the need to prepare for the future safety net that caters to citizenry welfare in challenging times.