bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of the Relationship Between of Dependent Personality Trait, Depression, Anxiety, and Stress Levels of Asthmatic and Non-Asthmatic Individuals
Authors: SEKİ ÖZ Hilal , AYDİN Cihan , AYHAN Didem 
Published: August 2022

Aim: There is a complex relationship between asthma and psychiatric problems; therefore, it is important to investigate this relationship for optimal treatment. In this cross-sectional and comparative study, it was aimed to examine the dependent personality trait, depression, anxiety and stress levels of asthmatic and non-asthmatic individuals.
Material and Method: 382 individuals with (n=172) and without (n=210) asthma were included in our study. The study data were collected with Identifying Information Form, Personality Belief Questionnaire, and Depression Anxiety Stress Scale (DASS) 21-Short Form. Comparisons between groups were made using the Chi-square test, Mann Whitney-U test, and Pearson correlation test.
Results: The mean age of the participants was 40.80±12.06, 45% of them were asthmatic, and the disease year was 7.92±8.49. It was observed that asthmatic individuals had high dependent personality trait and anxiety levels (p
Recalculated Orbits Of Binaries and New Linear Solutions
Authors: Cvetković Z. , Pavlović R. 
Published: August 2022

Abstract
In this paper we present recalculated orbital elements for nine binaries: EGG 2Aa, Ab, COU 1085, COU 1897, COU 1006, A 578Aa, Ab, A 1400, A 606, BU 984, and BU 992. Seven binaries have orbital periods longer than 100 yr, and two binaries have shorter orbital periods, 38 and 76 yr. Also, we present linear solutions determined for three double stars: COU 966, J838, and A 1247. In addition to the orbital elements for nine binaries, we give absolute magnitudes, spectral types, estimates of the masses, dynamical parallaxes, and for all 12 pairs the (O − C) residuals in θ and ρ.
Deliverable D3.8 A review of existing citizen science approaches to monitoring farmland biodiversity
Authors: Ruck Andrew , Öckinger Erik , van der Wal Rene , Mauchline Alice , Hood Amelia , Potts Simon , De Vries Michiel Wallis , Gaba Sabrina , Bretagnolle Vincent 
Published: August 2022

This report was researched and written between April and December 2021 by researchers at the Swedish University of Agricultural Sciences (SLU), with support from partners at the University of Reading (UK), De Vlinderstichting (Netherlands), and Centre National de la Recherche Scientifique (CNRS, France). The report consists of a review of existing 'citizen science’ approaches to monitoring biodiversity on farmland, in which we introduce a typology of five different types of approach, and highlight the strengths and weaknesses of these. This forms part of the project “SHOWCASing synergies between agriculture, biodiversity and Ecosystem services to help farmers capitalising on native biodiversity” (SHOWCASE). SHOWCASE aims to encourage the widespread uptake of biodiversity-friendly farming practices across Europe, both through identifying effective incentives for farmers, and gathering further evidence of the ecosystem services provided by increased levels of biodiversity. The project receives funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No.862480. In particular, this report fulfils Deliverable 3.8 within SHOWCASE: “A review of existing citizen science approaches to monitoring farmland biodiversity, including an overview of the different statistical approaches to handling citizen science data”. We at SLU are grateful to all SHOWCASE partners for their contributions.
Age-Stratified 30-day Rehospitalization and Mortality and Predictors of Rehospitalization Among Patients With Systemic Lupus Erythematosus: A Medicare Cohort Study
Authors: Schletzbaum Maria , Kind Amy J. , Chen Yi , Astor Brad C. , Ardoin Stacy P. , Gilmore-Bykovskyi Andrea , Sheehy Ann M. , Kaiksow Farah A. , Powell W. Ryan , Bartels Christie M. 
Published: August 2022

Objective Recent studies suggest young adults with systemic lupus erythematosus (SLE) have high 30-day readmission rates, which may necessitate tailored readmission reduction strategies. To aid in risk stratification for future strategies, we measured 30-day rehospitalization and mortality rates among Medicare beneficiaries with SLE and determined rehospitalization predictors by age. Methods In a 2014 20% national Medicare sample of hospitalizations, rehospitalization risk and mortality within 30 days of discharge were calculated for young (aged 18-35 yrs), middle-aged (aged 36-64 yrs), and older (aged 65+ yrs) beneficiaries with and without SLE. Multivariable generalized estimating equation models were used to predict rehospitalization rates among patients with SLE by age group using patient, hospital, and geographic factors. Results Among 1.39 million Medicare hospitalizations, 10,868 involved beneficiaries with SLE. Hospitalized young adult beneficiaries with SLE were more racially diverse, were living in more disadvantaged areas, and had more comorbidities than older beneficiaries with SLE and those without SLE. Thirty-day rehospitalization was 36% among young adult beneficiaries with SLE—40% higher than peers without SLE and 85% higher than older beneficiaries with SLE. Longer length of stay and higher comorbidity risk score increased odds of rehospitalization in all age groups, whereas specific comorbid condition predictors and their effect varied. Our models, which incorporated neighborhood-level socioeconomic disadvantage, had moderate-to-good predictive value (C statistics 0.67-0.77), outperforming administrative data models lacking comprehensive social determinants in other conditions. Conclusion Young adults with SLE on Medicare had very high 30-day rehospitalization at 36%. Considering socioeconomic disadvantage and comorbidities provided good prediction of rehospitalization risk, particularly in young adults. Young beneficiaries with SLE with comorbidities should be a focus of programs aimed at reducing rehospitalizations.
Pediatric Sarcoidosis: Retrospective Analysis of Biopsy-Proven Patients
Authors: Nott Kerstin , Nott Veronica , Lever Elliot , Deakin Claire , Galloway James , Fisher Corinne , Compeyrot-Lacassagne Sandrine 
Published: August 2022

ObjectiveTo describe the phenotype, disease course, and treatment of a large cohort of children with sarcoidosis.MethodsPatients with biopsies consistent with sarcoidosis, performed between 2010 and 2020, were included in this study. Patients’ notes were reviewed retrospectively. Children with disease onset before 5 years of age were compared with older children. Regression analysis was performed to determine predictors of treatment outcome.ResultsIn total, 48 children with a mean age at diagnosis of 9.5 years, with a male to female ratio of 0.71, were identified. In total, 72% of the children were of Black race and 94% had multiorgan disease, with an average of 4.8 organs involved, most commonly lymph nodes (65%), skin (63%), and eyes (60%). Laboratory findings of note included raised serum calcium in 23% of patients and raised angiotensin-converting enzyme in 76% of patients. Out of 14 patients tested, 6 had mutations inNOD2. In total, 81% of patients received systemic steroids and 90% received conventional disease-modifying antirheumatic drugs (DMARDs); in 25% of patients, a biologic was added, mostly anti–tumor necrosis factor (anti-TNF). Although most patients could be weaned off steroids (58%), most remained on long-term DMARDs (85%). Children under the age of 5 years presented more often with splenomegaly (P= 0.001), spleen involvement (P= 0.003), and higher C-reactive protein (P= 0.10). Weight loss was more common in adolescents (P= 0.006). Kidney (P= 0.004), eye (P= 0.005), and liver involvement (P= 0.03) were more common in Black patients. Regression analysis identified no single factor associated with positive treatment outcomes.ConclusionMultiorgan involvement, response to steroids, and chronic course are hallmarks of pediatric sarcoidosis. The phenotype significantly varies by age and race. Where conventional DMARDs were not efficacious, the addition of an anti-TNF agent was beneficial.
Case Report: Tuberculosis Autoregression after Minimal Treatment and Review of the Literature
Authors: Walter Chelsea , Acuña-Villaorduna Carlos , Hochberg Natasha S. , Sinha Pranay 
Published: August 2022

ABSTRACT.
Mycobacterium tuberculosis (Mtb) is a complex pathogen causing multiple possible disease states in its host including latency, active disease, and elimination. While there is reasonable indirect evidence of elimination of tuberculosis (TB) in the absence of treatment, direct reports of autoregression are rare. We report a case of smear-negative, polymerase chain reaction (PCR)-positive TB disease regression in the absence of therapy due to severe adverse effects from antimycobacterial drugs. Indirect reports of TB autoregression, or self-cure, in the literature are reviewed, and an updated framework for conceptualizing Mtb infection is discussed.
An Assessment of a Rapid SARS-CoV-2 Antigen Test in Bangladesh
Authors: Kawser Zannat , Hossain Mohabbat , Suliman Sara , Lockman Shahin , Gitaka Jesse , Bandawe Gama , Rahmat Redwan , Hasan Imrul , Siddik Abu Bakar , Afrad Mokibul Hassan , Rahman Mohammed Ziaur , Miller Glenn , Walt David R. , Ivers Louise C. , LaRocque Regina C. , Harris Jason B. , Qadri Firdausi 
Published: August 2022

ABSTRACT.
Early detection of SARS-CoV-2 infection is crucial to prevent its spread. This study aimed to document test sensitivity/specificity, correlation with cycle threshold value from polymerase chain reaction (PCR), fitness-for-use in different populations and settings, and user perspectives that could inform large-scale implementation. In this study, we evaluated the performance of a rapid antigen detection test, BD Veritor, and compared this (and another rapid test, Standard Q) against reverse transcription PCR (RT-PCR) in terms of sensitivity and specificity in 130 symptomatic and 130 asymptomatic adults. In addition, we evaluated the suitability and ease of use of the BD Veritor test in a subsample of study participants (n = 42) and implementers (n = 5). At 95% confidence interval, the sensitivity of the BD Veritor and Standard Q test were 70% and 63% in symptomatic and 87% and 73% in asymptomatic individuals, respectively, regarding positive SARS-CoV-2 RT-PCR results. Overall, the BD Veritor test was 78% sensitive and 99.5% specific compared with RT-PCR irrespective of the cycle threshold. This warrants large field evaluation as well as use of the rapid antigen test for quick assessment of SARS-CoV-2 for containment of epidemics in the country.
Murine Typhus in Latin America: Perspectives of a Once Recognized but Now Neglected Vector-Borne Disease
Authors: Faccini-Martínez Álvaro A. , Walker David H. , Blanton Lucas S. 
Published: August 2022

ABSTRACT.
Murine typhus is an undifferentiated febrile illness. Historically recognized throughout Latin America, it has been seldom reported in recent decades. When clinicians and researchers are attuned, endemic foci have reemerged. The demonstrable seroprevalence in areas devoid of reported cases indicates murine typhus is an underappreciated infectious disease in Latin America.
Two-Stage Detection of Plasmodium spp. by Combination of Recombinase Polymerase Amplification and Loop-Mediated Isothermal Amplification Assay
Authors: Lai Meng Yee , Lau Yee Ling 
Published: August 2022

ABSTRACT.
We developed a combination of recombinase polymerase and loop-mediated isothermal amplification methods (RAMP) for rapid screening of five human Plasmodium spp. simultaneously. RAMP is a two-stage isothermal amplification method, which consists of a first-stage recombinase polymerase amplification and a second-stage loop-mediated isothermal amplification. Under these two isothermal conditions, five Plasmodium spp. were amplified in less than 40 minutes. We demonstrated RAMP assay with 10-fold better limit of detection than a single (loop-mediated isothermal amplification) LAMP. As compared with microscopy, RAMP assay showed 100% sensitivity (95% CI: 95.65–100.00%) and 100% specificity (95% CI: 69.15–100.00%). The end products were inspected by the color changes of neutral red. Positive reactions were indicated by pink while the negative reactions remained yellow. The combination assay established in this study can be used as a routine diagnostic method for malaria.
SELECTED SCHOOL BASED FACTORS’ INFLUENCE ON VALUE ADDITION IN SECONDARY EDUCATION IN PUBLIC SECONDARY SCHOOLS IN RACHUONYO SOUTH SUB-COUNTY, KENYA
Authors: Odera Odera , Sika James , Olel Maureen 
Published: August 2022

Purpose: The study sought to determine value addition in secondary education of 2013 and 2014 cohorts in public secondary schools in Rachuonyo South Sub-county and to examine selected school based factors’ influence on value addition in secondary education.
Methodology: The study adopted a correlational design. Correlational research design was appropriate for this study since it enabled the researcher to collect independent and dependent variable data sets with a view to determine the relationship between them (Creswell, 2012). The population comprised 49 public secondary schools in Rachuonyo South Sub-County, 49 Deputy Principals and 5132 students. The researcher used Yamane’s formula to compute a sample of 39 public secondary schools, from where 39 Deputy Principals and 4351 students were purposively sampled. Data were collected using document analysis guide and questionnaires and analysed using frequencies, means and regression analysis with the aid of SPSS V.25 software.
Findings: Findings revealed value additions of -1.563125 for 2013 cohort. Regression analysis revealed that performance appraisal accounts for 17% change in value addition in secondary education of the 2013 cohort and that teachers’ professional development (β=0.325, p=0.040) has a weak significant positive relationship with value addition in secondary education of 2013 cohort. For the 2014 cohort, findings revealed value addition of -1.9363125. Regression analysis revealed that teachers’ performance appraisal account for 12% change in value addition in secondary education and that teachers’ performance appraisal (β=0.386, p=0.009) has a weak significant positive relationship with value addition in secondary education.
Unique contribution to model and practice: The study contributes to literature by providing analysis of value addition in secondary education and teacher performance appraisal contribution to value addition in the context of Kenya.
Pengaruh Model Pembelajaran Reciprocal Teaching terhadap Hasil Belajar Matematika Kelas V di SDN 23 Dompu
Authors: Sari Fifi Fitriana 
Published: August 2022

Tujuan dalam penelitian ini adalah Untuk mengetahui pengaruh model pembelajaran Reciprocal Teaching terhadap hasil belajar kelas V SDN 23 Dompu Tahun ajaran 2021/2022. Jenis pendekatan penelitian ini ialah penelitian kuantitatif. Bentuk penelitian ini menggunakan satu kelas dan, peneliti hanya mengfokuskan penelitian pada kelas V. Adapun tehnik pengumpulan data terdiri dari angket, tes dan dokumen, serta tehnik analisis data menggunakan Analisis regresi linear sederhana, Analisis koefisien korelasi, Anlisis koefisien determinasi, dan Pengujian hipotesis penelitian (uji T), dan fokus penyajian dalam penelitian ini adalah (1) Model Pembelajaran Reciprocal Teaching, (2) pemberian tes Reciprocal Teaching. Data tersebut dianalisis dengan mengunakan metode statistik yaitu dengan dengan nilai harga konstant α 54,89 > konstant harga b 0,640 dari hasil nilai harga konstant α hitung lebih besar dari konstant harga b maka data berdistribusi normal. Selanjutnya pengujian dilakukan menggunakan uji hipotesis (uji T) yaitu dapat melihat pengaruh penggunaan Model Pembelajaran Reciprocal Teaching, pernyataan tersebut ditandai dengan nilai thitung 0,766 > tabel 0,532 maka hipotesis diterima. Berdasarkan hasil analisis tersebut maka dapat dinyatakan bahwa ada pengaruh yang signifikan dengan taraf 0,05 atau 5% pada penggunaan Model Pembelajaran Reciprocal Teaching terhadap hasil belajar kelas V SDN 23 Dompu Tahun pelajaran 2021/2022.
MARCA TERRITORIAL COMO ESTRATÉGIA NOS PLANOS ESTADUAIS DE TURISMO: OS CASOS RN, RO E RS
Authors: Almeida Giovana Goretti Feijó de , Bridi Guilherme , Araújo Júnior Edson Modesto de , Silva Nayara Cristina Santana da , Damasceno Mellyssa Layla Barbosa 
Published: August 2022

O presente estudo contempla a discussão das relações entre planos estaduais de turismo e marcas territoriais na realidade de estados brasileiros. O objetivo é compreender se (e como) Rio Grande do Norte, Rondônia e Rio Grande do Sul estariam desenvolvendo seus planos de turismo estadual baseados nas marcas territoriais como estratégia para o desenvolvimento turí­stico, estendendo essa compreensão para o grau de inserção dessas marcas nesses documentos especí­ficos. A metodologia é de natureza qualitativa, sendo um estudo descritivo-explicativo. Utiliza-se de pesquisa bibliográfica e documental, com coleta de dados nos sites oficiais de turismo, além dos Planos Estratégicos e de Marketing Turí­stico e marcas territoriais adotadas nos três estados analisados. Faz-se a análiseÂ comparativa entre as realidades investigadas a partir do aprofundamento de oito categorias analí­ticas preestabelecidas. Os resultados apontam que o RN se encontra num patamar mais avançado nas estratégias para expansão de sua marca turí­stica. No RS, as ações de desenvolvimento do turismo vêm perdendo espaço, identificando-se a necessidade de recuperar e renovar sua marca.Â Já a realidade de RO revela que estado ainda se encontra num estágio inicial do desenvolvimento de ações estruturantes e estratégicas voltadas ao desenvolvimento de sua marca. A conclusão reitera a existência de marcas territoriais nos planos estaduais do turismo nos três estados do Brasil.
TINJAUAN YURIDIS TINDAK PIDANA MENIKAH TANPA IZIN DARI ISTRI YANG SAH DI KOTA MAKASSAR
Authors: Jannah Hamzah Andi Mursyidatul , Taba Hamzah , Zubaidah Siti 
Published: August 2022

This research aims to find out: 1) The elements of Article 279 of the Criminal Code can be proven in court decisions number 190/Pid. B/2017/ PN. Mks 2) the application of sanctions in Article 279 of the Criminal Code in cases of marriage without the wife's permission in Makassar City.
This research method is a type of qualitative research. The types of data used are primary data and secondary data, data from primary legal materials in the form of court decisions and laws and secondary legal materials referring to books, journals and other readings obtained from interviews with the Panel of Judges, Public Prosecutors, Police Investigators , Head of KUA, and Imam of Kelurahan to complete the required information.
The results of this research indicate that: 1) Specifically the defendant in the court decision number 190/Pid. B/2017/ PN. Mks is considered to have fulfilled the elements of Article 279 Paragraph (2) of the Criminal Code after the Public Prosecutor was able to prove it with evidence in the form of witness statements, letters and statements from the defendant which were mutually compatible. 2) The application of sanctions in Article 279 of the Criminal Code in cases of marriage without the wife's permission in this study the criminal penalty applied is imprisonment. Based on the theory of sentencing theory, the judge's verdict on the criminal act of marrying without the wife's permission is more likely to be in accordance with the relative theory or purpose (Doel Theorien). In addition, differences in the application of criminal sanctions (disparity) were also found. This happened apart from the judge's consideration factor, the disparity was also inseparable from the Public Prosecutor's demand factor.
Analysis of Nutritional Factors and Physical Conditions Affecting Growth and Monoclonal Antibody Production of the Hybridoma KB‐26.5 Cell Line
Authors: Sanfeliu Anna , Cairó Jordi J. , Casas Carles , Solà Carles , Gòdia Francesc 
Published: July 2002

AbstractThe effect of medium composition and physical conditions on the growth pattern and monoclonal antibody production of the hybridoma cell line KB‐26.5 has been studied in batch and fed‐batch cultures. Different aspects have been analyzed both individually and in combination, as it is expected that not only one component plays a predominant role in this process but a combination of a number of them. Modification of the concentrations of glucose and glutamine, supplementation of the medium with vitamins and amino acids, influence of lactate and ammonium accumulation, and pulse addition of fetal calf serum have been studied in detail, contributing to an improvement in the cell growth and IgG3 production. Finally, the combined effect of all these factors in a fed‐batch culture leads clearly to a major improvement in the cultures, with a 10‐fold increase in the final monoclonal antibody concentration with respect to nonoptimized batch experiments.
Sequential δ‐Integration for the Regulated Insertion of Cloned Genes in Saccharomyces cerevisiae
Authors: Lee Frank W. F. , Da Silva Nancy A. 
Published: July 2002

AbstractA novel δ‐integration vector was developed to allow the sequential insertion of multiple cloned genes in the yeast Saccharomyces cerevisiae. To allow repetitive integrations, the reusable URA3 Blaster selection cassette was employed; the insertions (of CUP1p‐lacZ in this study) were selected using the URA3 marker which was subsequently “popped” out by recombination between flanking direct repeats. Transformants contained only one new integrated copy after the loss of the URA3 marker, and subsequent transformations were effective for the sequential insertion of a series of genes (one at a time) into dispersed chromosomal δ sequences. The structural stability of the integrations was location‐dependent (ranging from 75% to 100% after 50 generations in complex medium with or without gene expression), and the integrations (at least up to five) had no significant effects on the growth of the cells. In addition, β‐galactosidase specific activity levels varied linearly with integrated copy number. The repetitive, regulated nature of integration with this vector is not possible with traditional δ‐integration or other homologous recombination methods, and is promising for fine‐tuning cloned gene copy number and for the insertion of metabolic pathway genes.
A new in vitro model for the study of microbial microleakage around dental restorations: a preliminary qualitative evaluation
Authors: Matharu S. , Spratt D. A. , Pratten J. , Ng Y‐L. , Mordan N. , Wilson M. , Gulabivala K. 
Published: July 2002

AbstractAimThe aim of this study was to develop an in vitro model to replicate microbial microleakage at a tooth/restoration interface using a constant depth film fermentor (CDFF).MethodologyAmalgam restorations were placed in machined bovine dentine cylinders and sealed externally with varnish, leaving a 1‐mm perimeter exposed around the tooth/restoration interface. The dentine cylinders were housed in a CDFF and 300‐µm thick microcosm dental plaques were grown over their exposed surfaces. The biofilms were maintained with a mucin‐containing artificial saliva for up to 8 weeks. Cylinders were aseptically removed from the CDFF (at 1, 2, 4, & 8 weeks) and surface‐decontaminated with validated protocols prior to splitting and sampling of apposing amalgam and dentine surfaces. Scanning electron microscopy (SEM) was used to ascertain the position and structure of the bacterial aggregates. Bacterial viability was determined by vital staining of the bacteria in situ.ResultsAt all sampling times, SEM showed cocci, rods and filaments on both amalgam and dentine surfaces; some originated as cascades from the surface biofilm and extended into the tooth/restoration microspace. Vital staining showed the majority of bacteria from both dentine and amalgam surfaces to be viable.ConclusionThis preliminary investigation showed that the CDFF may be a valuable tool for the in vitro study of the dynamics of microbial microleakage around dental restorations.