bluuebunny/crossref_metadata_2025_split huggingface dataset:
DETEKSI BAKTERI Staphylococcus sp. PENYEBAB JERAWAT DENGAN TINGKAT PENGETAHUAN PERAWATAN WAJAH PADA SISWA KELAS XI DI SMK NEGERI 1 PAGERWOJO
Authors: IMASARI TRIFFIT , Emasari Ficka 
Published: August 2022

Jerawat merupakan penyakit kulit yang sering terjadi pada masa remaja bahkan hingga dewasa yang ditandai dengan adanya komedo, papul, pustul, nodus, dan kista pada daerah wajah, leher, lengan atas, dada, dan punggung. Faktor-faktor penyebab timbulnya jerawat antara lain seperti faktor genetik, hormon, makanan, kondisi kulit , psikis, cuaca, infeksi bakteri Staphylococcus sp, pekerjaan, kosmetika dan bahan kimia yang lain. Kebersihan wajah bertujuan untuk mengurangi bakteri atau mikroorganisme dari permukaan kulit dengan cara mengurangi sebum dan kotoran tanpa menghilangkan lipid barrier kulit. Kebersihan wajah yang optimal didukung dengan cara perawatan kulit wajah dengan menggunakan pembersih. Tujuan penelitian yaitu untuk mengidentifikasi adanya Staphylococcus sp. penyebab timbulnya jerawat dan untuk mengetahui korelasi bakteri Staphylococcus sp.dengan tingkat pengetahuan perawatan wajah siswa kelas XI SMK Negeri 1 Pagerwojo Tulungagung. Metode penelitian ini analitik korelasi dengan menggunakan teknik purposive sampling dan sampel yang digunakan sebanyak 14 sampel. Sampel yang digunakan yaitu swab dari penderita jerawat. Penelitian ini dilakukan menggunakan metode uji biakkan kultur pada media BAP, MSA, NAS dan pewarnaan Gram serta kuisioner untuk mengertahui tingkat pengetahuan perawatan wajah. Hasil penelitian yaitu teridentifikasi bakteri Gram positif Staphylococcus aureus sebesar 79% dan Staphylococcus albus sebesar 21% penyebab timbulnya jerawat serta hasil kuisioner pengetahuan perawatan wajah pada siswa kelas XI dengan kategori cukup 78%. Kesimpulan dari penelitian ini yaitu terdapat Staphylococcus aureus dan Staphylococcus albus penyebab timbulnya jerawat dan tidak ada korelasi adanya bakteri Staphylococcus sp dengan tingkat pengetahuan perawatan wajah pada siswa kelas XI di SMKN 1 Pagerwojo Tulungagung
THE EFFECT OF PHYSICAL ACTIVITY AND IMT ON BLOOD GLUCOSE LEVELS AND HYPERTENSION
Authors: Purnadianti Mely , Riyaniarti Maria , Tuna Hartati , Hermawan Rizal Aditya , Hayuningrum Adilia 
Published: August 2022

Aktivitas fisik merupakan gerakan tubuh oleh otot rangka yang bekerja dan memerlukan energi yang meliputi seluruh kegiatan di rumah, di tempat kerja, atau aktivitas lainnya. Aktivitas fisik dapat berpengaruh pada metabolisme tubuh. Aktivitas fisik kurang dapat berpengaruh pada metabolisme tubuh yang disebabkan oleh energi yang masuk dan keluar tidak seimbang serta dapat mempengaruhi indeks massa tubuh. Jika berlangsung lama dan tanpa ada perbaikan, dapat berpengaruh pada kadar glukosa darah, kerja insulin serta reseptor – reseptornya. Kerja insulin den reseptor yang terganggu dapat menimbulkan hiperglikemia. Kadar glukosa darah tinggi yang tidak terkontrol dapat memicu terbentuknya AGEs, yaitu zat yang dibentuk dari gula yang berlebih dan protein pada pembuluh darah. AGEs dapat merusak dinding pembuluh darah dan menarik lemak jenuh sehingga terbentuk plaq yang menghambat aliran darah sehingga tekanan darah meningkat dan menjadi hipertensi. Tujuan penelitian ini untuk mengetahui gambaran pengaruh aktivitas fisik dan IMT terhadap peningkatan glukosa darah dan hubungannya dengan hipertensi pada wanita dewasa. Penelitian ini menggunakan desain penelitian Cross Sectional dan metode penelitian deskriptif dengan pendekatan kuantitatif. Hasil penelitian berdasarkan uji statistik yaitu terdapat pengaruh hubungan antara aktivitas fisik dan IMT terhadap peningkatan glukosa darah dengan p-value 0.001 tetapi tidak terdapat hubungan antara glukosa darah dengan hipertensi dengan p-value 0.336.
PERBANDINGAN KADAR HEMOGLOBIN PADA PEROKOK BERDASARKAN USIA DI RSUD NGANJUK
Authors: Andayani Anik 
Published: August 2022

Merokok adalah suatu kebiasaan yang mengganggu dan merugikan kesehatan. Merokok dapat dilakukan oleh berbagai macam kalangan usia. Kebiasaan merokok bagi perokok aktif maupun kebiasaan menghirup asap rokok yang tidak di sengaja bagi perokok pasif adalah salah satu faktor yang dapat meningkatkan kadar karbon monoksida di dalam tubuh. Penelitian ini bertujuan untuk mengetahui Perbandingan Kadar Hemoglobin Berdasarkan Usia Di Rumah Sakit Umum Daerah Nganjuk. Desain penelitian yang digunakan oleh peneliti yaitu Cross sectional survey. Teknik sampling yang dilakukan dengan non-probability sampling dengan cara Purposive sampling. Pengambilan data hasil pemeriksaan dilakukan pada bulan April 2021. Pada penelitian ini terdapat 64 responden yang berpartisipasi. Berdasarkan analisa data yang telah dilakukan diperoleh kadar kadar Hemoglobin rata-rata adalah 14.43 g/dL. Berdasarkan nilai probabilitas atau p value dengan uji komparasi Mann-Whitney, hasil= 0,000 . Dimana hasil ini <0,05 artinya terdapat perbandingan yang bermakna antara dua variabel yang diuji. Jadi interpretasi hasil uji hipotesa adalah H0 ditolak, artinya ada Perbandingan antara Kadar Hemoglobin Berdasarkan Usia Di Rumah Sakit Umum Daerah Nganjuk.
Optimalisasi ekstraksi kulit bawang merah (Allium cepa L) menggunakan metode maserasi
Authors: Badriyah Lailatul , Farihah Dewi 
Published: August 2022

Bawang merah diambil bagian umbi, untuk bagian kulit bawang merah penggunaanya masih terbatas. Kulit bawang merah (Allium cepa L.) merupakan limbah yang belum dimanfaatkan. Tujuan Penelitian ini untuk mengetahui pelarut antara ekstrak etanol 96%, ekstrak air, ekstrak campuran etanol 96%-air menghasilkan ekstrak kulit bawang merah (Allium cepa L.) paling tinggi dan mengetahui perbedaan kandungan golongan senyawa kimia dari ekstrak etanol 96%, ekstrak air, ekstrak campuran etanol 96% dan air pada kulit bawang merah (Allium cepa L.). Penelitian dilakukan secara eksperimen, sampel di ekstraksi dengan cara di maserasi selama 3 X 24 jam dengan menggunakan pelarut etanol 96%, pelarut air dan pelarut campuran etanol-air. Hasil rata-rata rendemen ekstrak etanol 96% 10,66%, ekstrak air 10,29% dan ekstrak campuran etanol-air 13,27%. Berdasarkan hasil penelitian bahwa rendemen optimal pada ekstraksi kulit bahwa merah menggunakan pelarut campuran etanol-air yaitu sebesar 13,27% dengan analisis fitokimia secara kualitatif mengandung senyawa alkaloid, flavonoid, saponin.

Kata Kunci : Ekstrak Kulit Bawang Merah, maserasi, pelarut
Study the Impact of Cramming in Medical Students
Authors: Siagian Forman Erwin 
Published: August 2022

Aim: To reveal pre- exam cramming among pre-clinical medical students, what drives this practice, failure due to cramming and the problems and difficulties related to the act of cramming.
Discussion: Cramming is common practice among struggling medical students. The prevalence of cramming is like an iceberg phenomenon. The act of stacking too many information just the night before an exam probably authorize the perpetrator to remember some information in the short term period and enable them to take in enough information for the exam. Along with this practice also comes sleep deprivation, mental and emotional disturbances and even substance abuse in order to achieve good marks and passing the exam. Unfortunately for some experts, cramming is not considered as learning. Procrastination and some other reason are believed to be the reason the culprit commits cramming.
Conclusion: Cramming not only changes the behavior of the perpetrator, but also has an impact on his family, classmates, environment and future.
Studies on Genetic Variability in Ridge Gourd (Luffa acutangula L. Roxb.) under Prayagraj Agro-Climatic Condition
Authors: Yadav Anirudh , Singh Devi 
Published: August 2022

Aim: To study the genetic variability of ridge gourd uber Prayagraj Agro-climatic condition.
Study Design: Randomised Complete Block Design (RCBD).
Place and Duration of Study: Horticultural Research Farm, Department of Horticulture, Naini Agricultural Institute, SHUATS, Prayagraj. Between August 2021 to October 2021.
Methodology: 11 genotypes of fennel were sown in three replications in RCB design. In each replication data were observed on five plants and averaged for all 21 characters under study.
Results: Analysis of variance showed the presence of significant variation among different genotypes for all characters studied. Days to germination and plant height [30DAS] exhibited high estimates of GCV and PCV both. Genetic parameters revealed that high heritability (broad sense) was observed for fruit yield per hectare, plant height [30DAS], fruit length, plant height [60DAS], days to first harvest of fruits, days to germination, leaf length, sex ratio, fruit girth, fruit yield per plant, days to first male flowering, shelf life, leaf per plant [30DAS], Vitamin C content and number of primary branches per plant. Fruit yield per hectare, fruit yield per plant, fruit girth, fruit length, leaf length, plant height [60DAS], plant height [30DAS] and days to germination exhibited high heritability broad sense coupled with high values for genetic advance as percent of mean.
Conclusion: Selection in these traits will lead to higher efficiency in breeding programme for improving yield. Thus these traits may be ranked as most important attributing traits for seed yield per plant in fennel.
A Rare Breast Carcinosarcoma in a Young Female
Authors: Al-Share Mohammad , Al-Awabdeh Michleen , Al-Khalaileh Maysaa , Abu-Jeyyab Mohammad , Al-Asbahi Hanan 
Published: August 2022

Metaplastic breast cancer (MBC) is a rare aggressive type of breast cancer, as this form of cancer makes up only 1% of overall breast cancers. It mainly presents with a rapid-growing mass. Establishing the diagnosis is based on histopathology, as imaging studies show the same features as other types of breast cancer. The treatment protocol for MBC is similar to those for invasive ductal carcinomas owing to the lack of standardized management modality for metaplastic breast cancer per se.
Study on Frequency of Impaired Lung Function in Treated Tuberculosis Patients in Tertiary Care Hospital of Pakistan
Authors: Hussain Riaz , Hussain Sagheer , Baig Mirza Saifullah , Rao Nisar Ahmed , Ali Rizwan , Ali Safdar , Qalb-i-Hyder Syed 
Published: August 2022

Background: Pulmonary impairment is a common manifestation in previously treated pulmonary tuberculosis (PTB) patients. Approximately 40-60% of patients with history of complete anti-tuberculosis therapy (ATT) developed the obstructive, restrictive or mixed patterns of lung disease.
Objective: To determine the frequency and type of impairment of lung function in previously treated PTB patients.
Methods: A descriptive cross-sectional study was conducted at Ojha Institute of Chest diseases, Dow University of Health Sciences, Karachi during the period of six months from April 2021 to September 2021. One hundred and forty four previously treated PTB patients with age of 18-60 years were selected through consecutive sampling. Spirometry of each patient was performed by trained spirometry technician and lung function was assessed by an experienced pulmonologist. Data was interpreted with SPSS v. 25.0.
Results: Out of 144 previously treated PTB patients, male were 83 (57.6%) and female were 61 (42.4%). Impaired pulmonary function was present in 87 (60.4%) patients, out of which 49 (56.3%) patients had obstructive impairment; 23 (26.4%) patients had restrictive impairment while 15 (17.2%) patients had mix pattern.
Conclusion: Prevalence rate of impaired pulmonary function was higher in treated PTB patients who have completed ATT. Obstructive pulmonary impairment was the most common pulmonary impairment followed by restrictive and mixed pulmonary impairment.
Origin of Lithiophilicity of Lithium Garnets: Compositing or Cleaning?
Authors: Zheng Hongpeng , Li Guoyao , Ouyang Runxin , Han Yao , Zhu Hong , Wu Yongmin , Huang Xiao , Liu Hezhou , Duan Huanan 
Published: August 2022

AbstractGarnet‐type Li6.5La3Zr1.5Ta0.5O12 (LLZTO), a promising solid‐state electrolyte, is reported to exhibit lithiophobicity. Herein, it is demonstrated that the origin of the lithiophobicity is closely related to the surface compositions of both the lithium and LLZTO. Surface impurities with high melting points such as Li2O, Li2CO3, LiOH, or LiF inhibit the wettability between lithium metal and LLZTO, and the widely adopted compositing strategy may improve the wettability by merely breaking the surface impurity layers. A simple but effective “polishing‐and‐spreading” strategy is proposed to remove the surface impurities and obtain clean Li/LLZTO interfaces. Thus, a tight and continuous Li/LLZTO interface with an interfacial resistance of 17.5 Ω cm2 is achieved, which leads to stable cycling of the symmetric Li cells and a critical current density up to 2.8 mA cm–2. This work provides a new perspective to understand the lithiophilicity of garnet‐type electrolytes and contributes to designing robust Li/garnet interfaces.
Transient Photodegradability of Photostable Gel Induced by Simultaneous Treatment with Acid and UV–Light for Phototuning of Optically Functional Materials
Authors: Russell Go M. , Kaneko Takashi , Ishino Saqura , Masai Hiroshi , Terao Jun 
Published: August 2022

AbstractAlthough photodegradability is promising for on‐demand tuning of material properties, phototuned materials cannot be utilized under ambient light irradiation owing to their photoinstability. Herein, a novel photostable gel that photodegrades only in the presence of an acid is fabricated. The unique reactivity of a supramolecular platinum‐acetylide complex is uncovered to incorporate into poly(methyl methacrylate) gel as the cross‐linker to exhibit softening and swelling under simultaneous treatment with UV‐light and acid. Conversely, when the acid is removed, the gel reacquires its photostability. A cross‐linker amount of only 0.7 wt.% is sufficient to realize the material property. Notably, the unique cross‐linkers, which change phosphorescence to fluorescence via photocleaving of PtC bonds, enable a photoprocess of optical functions. The controllable optical properties can be applied to information hiding technology and in visualizing the locally modified elasticity of the material, because of the photostability in absence of the acid.
Regulating Competitive Doping in Solution‐Mixed Conjugated Polymers for Dramatically Improving Thermoelectric Properties
Authors: Suh Eui Hyun , Kim Sang Beom , Yang Han Sol , Jang Jaeyoung 
Published: August 2022

AbstractLargely soluble tris(pentafluorophenyl)borane (BCF) has recently emerged as a promising molecular dopant for preparing highly conductive organic thermoelectrics (TEs) using a one‐step solution‐mixing method. However, the unique doping mechanisms that include both undesirable Lewis acid doping with BCF and effective Brønsted acid doping with BCF–water complexes limit its widespread applications. Herein, the feasibility of modulating the two doping mechanisms by utilizing the competitive Lewis acid–base interactions of BCF with H2O or Lewis basic groups in conjugated polymers is demonstrated. The polymer without strong Lewis basic groups undergoes Brønsted acid doping, which efficiently forms delocalized free charge carriers and leads to superior TE power factors and figures of merit of 49.6 µW m−1 K−2 and 0.061, respectively. However, the polymer with strong Lewis basic groups undergoes both doping mechanisms competitively. BCF–polymer Lewis complexes not only generate free charge carriers inefficiently, but also hinder possible Brønsted acid doping and localize charge carriers, significantly lowering the TE properties. Nevertheless, the reduced TE properties can be dramatically improved by thermally annealing the predoped polymer films because Lewis acid doping can be substantially replaced by Brønsted acid doping owing to the different thermal stabilities between the BCF–polymer and BCF–water complexes.
Synthesis of Perdeuterated Linoleic Acid‐d31 and Chain Deuterated 1‐Palmitoyl‐2‐linoleoyl‐sn‐glycero‐3‐phosphocholine‐d62
Authors: Moir Michael , Yepuri Nageshwar Rao , Marshall David L. , Blanksby Stephen J. , Darwish Tamim A. 
Published: August 2022

AbstractHerein, we report a gram‐scale synthesis of perdeuterated linoleic acid‐d31. The starting materials for the synthesis are two saturated fatty acids, azelaic acid‐d14 and pentanoic acid‐d9, which can be obtained by metal catalysed hydrothermal hydrogen‐deuterium exchange. The synthesis utilises the fatty acids directly via decarboxylative coupling. Copper catalysed coupling of a terminal alkyne intermediate with a propargyl bromide derivative affords a skipped diyne, which can be reduced using P‐2 nickel to obtain the desired cis,cis‐diene geometry. The subsequent synthesis of the tail‐deuterated phospholipid, 1‐palmitoyl‐2‐linoleoyl‐sn‐glycero‐3‐phosphocholine‐d62 (PLPC‐d62) is also described. Optimised reaction conditions were developed to access this phospholipid and its regioisomeric purity was characterised by two complementary mass spectrometry techniques.magnified image
Nonmalignant respiratory disease mortality in male Colorado Plateau uranium miners, 1960–2016
Authors: Kelly‐Reif Kaitlin , Bertke Stephen , Daniels Robert D. , Richardson David B. , Schubauer‐Berigan Mary K. 
Published: August 2022

AbstractBackgroundTo evaluate trends of nonmalignant respiratory disease (NMRD) mortality among US underground uranium miners on the Colorado Plateau, and to estimate the exposure–response association between cumulative radon progeny exposure and NMRD subtype mortality.MethodsStandardized mortality ratios (SMRs) and excess relative rates per 100 working level months (excess relative rate [ERR]/100 WLM) were estimated in a cohort of 4021 male underground uranium miners who were followed from 1960 through 2016.ResultsWe observed elevated SMRs for all NMRD subtypes. Silicosis had the largest SMR (n = 52, SMR = 41.4; 95% confidence interval [CI]: 30.9, 54.3), followed by other pneumoconiosis (n = 49, SMR = 39.6; 95% CI: 29.6, 52.3) and idiopathic pulmonary fibrosis (IPF) (n = 64, SMR = 4.77; 95% CI 3.67, 6.09). SMRs for silicosis increased with duration of employment; SMRs for IPF increased with duration of employment and calendar period. There was a positive association between cumulative radon exposure and silicosis with evidence of modification by smoking (ERR/100 WLM≥10 pack‐years = 0.78; 95% CI: 0.05, 24.6 and ERR/100 WLM<10 pack‐years = 0.01; 95% CI: −0.03, 0.52), as well as a small positive association between radon and IPF (ERR/100 WLM = 0.06, 95% CI: 0.00, 0.24); these associations were driven by workers with prior employment in hard rock mining.ConclusionsUranium mining workers had excess NMRD mortality compared with the general population; this excess persisted throughout follow‐up. Exposure‐response analyses indicated a positive association between radon exposure and IPF and silicosis, but these analyses have limitations due to outcome misclassification and missing information on occupational co‐exposures such as silica dust.
Radical Hydro‐Fluorosulfonylation of Unactivated Alkenes and Alkynes
Authors: Wang Peng , Zhang Honghai , Zhao Mingqi , Ji Shuangshuang , Lin Lu , Yang Na , Nie Xingliang , Song Jinshuai , Liao Saihu 
Published: August 2022

AbstractRecently, radical fluorosulfonylation is emerging as an appealing approach for the synthesis of sulfonyl fluorides, which are highly in demand in various disciplines, particularly in chemical biology and drug discovery. Here, we report the first establishment of radical hydro‐fluorosulfonylation of alkenes, which is enabled by using 1‐fluorosulfonyl 2‐aryl benzoimidazolium (FABI) as an effective redox‐active radical precursor. This method provides a new and facile approach for the synthesis of aliphatic sulfonyl fluorides from unactivated alkenes, and can be further applied to the late‐stage modifications of natural products and peptides, as well as ligation of drugs in combination with click chemistry. Remarkably, this system could enable the radical hydro‐fluorosulfonylation of alkynes, affording valuable alkenylsulfonyl fluoride products with a rare, highZ‐selectivity, which are normally less stable and more challenging to synthesize in comparison with theE‐configured products.
Role, relevance, and possibilities of in vitro fermentation models in human dietary, and gut‐microbial studies
Authors: Singh Vineet , Son HyunWoo , Lee GyuDae , Lee Sunwoo , Unno Tatsuya , Shin Jae‐Ho 
Published: August 2022

AbstractDietary studies play a crucial role in determining the health‐benefiting effects of most food substances, including prebiotics, probiotics, functional foods, and bioactive compounds. Such studies involve gastrointestinal digestion and colonic fermentation of dietary substances. In colonic fermentation, any digested food is further metabolized in the gut by the residing colonic microbiota, causing a shift in the gut microenvironment and production of various metabolites, such as short‐chain fatty acids. These diet‐induced shifts in the microbial community and metabolite production, which can be assessed through in vitro fermentation models using a donor's fecal microbiota, are well known to impact the health of the host. Although in vivo or animal experiments are the gold standard in dietary studies, recent advancements using different in vitro systems, like artificial colon (ARCOL), mini bioreactor array (MBRA), TNO in vitro model of the colon (TIM), Simulator of the Human Intestinal Microbial Ecosystem (SHIME), M‐SHIME, Copenhagen MiniGut, and Dynamic Gastrointestinal Simulator, make it easy to study the dietary impact in terms of the gut microbiota and metabolites. Such a continuous in vitro system can have multiple compartments corresponding to different parts of the colon, that is, proximal, transverse, and distal colon, making the findings physiologically more significant. Furthermore, postfermentation samples can be analyzed using metagenomic, metabolomic, quantitative‐polymerase chain reaction, and flow‐cytometry approaches. Moreover, studies have shown that in vitro results are in accordance with the in vivo findings, supporting their relevance in dietary studies and giving confidence that shifts in metabolites are only due to microbes. This review meticulously describes the recent advancements in various fermentation models and their relevance in dietary studies.
Transforming silicon slag into high‐capacity anode material for lithium‐ion batteries
Authors: Vanpeene Victor , Heitz Alexandre , Herkendaal Natalie , Soucy Patrick , Douillard Thierry , Roué Lionel 
Published: August 2022

AbstractThe conception of cheaper and greener electrode materials is critical for lithium (Li)‐ion battery manufacturers. In this study, a by‐product of the carbothermic reduction of SiO2 to Si, containing 65 wt% Si, 31 wt% SiC, and 4 wt% C, is evaluated as raw material for the production of high‐capacity anodes for Li‐ion batteries. After 20 h of high‐energy ball milling, C is fully converted to SiC and a micrometric powder (D50 ∼1 μm) is obtained in which submicrometric SiC inclusions are embedded in a nanocrystalline/amorphous Si matrix. This material is able to maintain a capacity >1000 mAh g−1 (>3 mAh cm−2) over 100 cycles. No crystalline Li15Si4 phase is formed upon cycling as shown from the differential dQ/dV curves. The good mechanical resiliency of the electrode is evidenced by monitoring its morphological changes from sequential focused ion beam scanning electron microscopy analyses. However, a progressive and irreversible increase in the electrode mass and thickness is observed over cycling (reaching 125% and 60% after 200 cycles, respectively), which is mainly attributed to the accumulation of solid electrolyte interphase products in the electrode.