bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evidence-based practice and management-by-knowledge of disability care: rigid constraint or fluid support?
Authors: Pistone Isabella , Lidström Allan , Bohlin Ingemar , Schneider Thomas , Zuiderent-Jerak Teun , Sager Morten 
Published: January 2022

Background:Although increasingly accepted in some corners of social work, critics have claimed that evidence-based practice (EBP) methodologies run contrary to local care practices and result in an EBP straitjacket and epistemic injustice. These are serious concerns, especially in relation to already marginalised clients.
Aims and objectives:Against the backdrop of criticism against EBP, this study explores the ramifications of the Swedish state-governed knowledge infrastructure, ‘management-by-knowledge’, for social care practices at two care units for persons with intellectual disabilities.
Methods:Data generated from ethnographic observations and interviews were analysed by applying a conceptual framework of epistemic injustice; also analysed were national, regional and local knowledge products within management-by-knowledge related to two daily activity (DA) units at a social care provider in Sweden.
Findings:In this particular case of disability care, no obvious risks of epistemic injustice were discovered in key knowledge practices of management-by-knowledge. Central methodologies of national agencies did include perspectives from social workers and clients, as did regional infrastructures. Locally, there were structures in place that focused on creating a dynamic interplay between knowledge coming from various forms of evidence, including social workers’ and clients’ own knowledge and experience.
Discussion and conclusions:Far from being a straitjacket, in the case studied management-by-knowledge may be understood as offering fluid support. Efforts which aim at improving care for people with disabilities might benefit from organisational support structures that enable dynamic interactions between external knowledge and local practices.
Magnitude and associated factors of Intestinal Parasitosis and Tuberculosis among Tuberculosis suspected patients attending Kuyu General Hospital, North Shewa, Oromia, Ethiopia
Authors: Tesfaye Sahilu , zerfu Biruk , Desta Kassu 
Published: January 2022

Background
Intestinal parasites and Tuberculosis (TB) co-infection is a major public health problem. The parasitic infection suppresses the cell mediated immunity that protects tuberculosis. Helminthes-induced immune modulation promotes progression to active tuberculosis. However, there is paucity of evidences on the intestinal parasites-tuberculosis co-infection in Ethiopia. This study explores the magnitude and associated factors of intestinal parasitic infection and TB among suspected pulmonary Tuberculosis (PTB) patients.

Methodology
A cross-sectional study design was conducted in Kuyu General Hospital from December 2019—March 2020. The socio-demographic data and associated factors were collected by structured questionnaire and then spot-spot sputum and fresh stool samples were collected following standard guidelines and were processed. Descriptive analysis was conducted and reported in frequency and percentage. Bivariate analysis was computed and a multivariable analysis was conducted to provide an adjusted odds ratio (AOR). P-value <0.05 at 95% confidence interval was considered as statistically significant.

Results
The burden of intestinal parasites was 20.2% (49/ 242) and 6.1% (20/ 242) of them were helminths infections and 14.1% (29/ 242) were protozoa infections. Of 242 patients, 14.9% (36/242) were sputum smear-positive for acid fast-bacilli. Of 36 smear positive patients, 9(25%) had TB–intestinal parasites co-infection. Dwelling in rural areas and having untrimmed fingernails were statistically significantly associated with intestinal parasites. Having a contact history of Tb patients was significantly associated with pulmonary tuberculosis.

Conclusions
The magnitude of intestinal parasites and TB among PTB suspected patients were high. Hookworm infection was the predominant helmenthic infection. It is important to consider screening TB patients for intestinal parasites and treat co-infection properly.
The Australian living guidelines for the clinical care of people with COVID-19: What worked, what didn’t and why, a mixed methods process evaluation
Authors: Turner Tari , Elliott Julian , Tendal Britta , Vogel Joshua P. , Norris Sarah , Tate Rhiannon , Green Sally ,   on behalf of the National COVID-19 Clinical Evidence Taskforce
Published: January 2022

IntroductionThe Australian National COVID-19 Clinical Evidence Taskforce is producing living, evidence-based, national guidelines for treatment of people with COVID-19 which are updated each week. To continually improve the process and outputs of the Taskforce, and inform future living guideline development, we undertook a concurrent process evaluation examining Taskforce activities and experience of team members and stakeholders during the first 5 months of the project.MethodsThe mixed-methods process evaluation consisted of activity and progress audits, an online survey of all Taskforce participants; and semi-structured interviews with key contributors. Data were collected through five, prospective 4-weekly timepoints (beginning first week of May 2020) and three, fortnightly retrospective timepoints (March 23, April 6 and 20). We collected and analysed quantitative and qualitative data.ResultsAn updated version of the guidelines was successfully published every week during the process evaluation. The Taskforce formed in March 2020, with a nominal start date of March 23. The first version of the guideline was published two weeks later and included 10 recommendations. By August 24, in the final round of the process evaluation, the team of 11 staff, working with seven guideline panels and over 200 health decision-makers, had developed 66 recommendations addressing 58 topics. The Taskforce website had received over 200,000 page views. Satisfaction with the work of the Taskforce remained very high (>90% extremely or somewhat satisfied) throughout. Several key strengths, challenges and methods questions for the work of the Taskforce were identified.ConclusionsIn just over 5 months of activity, the National COVID-19 Clinical Evidence Taskforce published 20 weekly updates to the evidence-based national treatment guidelines for COVID-19. This process evaluation identified several factors that enabled this achievement (e.g. an extant skill base in evidence review and convening), along with challenges that needed to be overcome (e.g. managing workloads, structure and governance) and methods questions (pace of updating, and thresholds for inclusion of evidence) which may be useful considerations for other living guidelines projects. An impact evaluation is also being conducted separately to examine awareness, acceptance and use of the guidelines.
Social jetlag and sleep debts are altered in different rosters of night shift work
Authors: Casjens Swaantje , Brenscheidt Frank , Tisch Anita , Beermann Beate , Brüning Thomas , Behrens Thomas , Rabstein Sylvia 
Published: January 2022

Background
Night and shift work are suspected to cause various adverse effects on health and sleep. Sleep deprivation through shift work is assumed to be compensated on free days. So far it is not clear how different shift systems and shift lengths affect sleep structure on work and free days. Especially working night shifts disrupts the circadian rhythm but also extended working hours (12h) might affect sleep characteristics. Hitherto, the magnitude of sleep debt, social jetlag, and Locomotor Inactivity During Sleep (LIDS) in different shift systems is unknown.

Methods
Here, we investigated the impact of five different shift rosters on sleep in 129 industrial workers from Germany. Permanent night work with multiple shift systems with and without night shifts and with different shift lengths were compared. Wrist-activity was monitored over 28 days revealing sleep on- and offsets as well as LIDS as proxy for sleep quality. Overall, 3,865 sleep bouts comprising 22,310 hours of sleep were examined.

Results
The mean daily age-adjusted sleep duration (including naps) was 6:43h and did not differ between shift workers of different rosters. However, sleep duration on workdays was particularly low in rotational shift systems with 12h-shifts (5:00h), while overall sleep debt was highest. Shift workers showed a median absolute social jetlag of 3:03h, which differed considerably between shift types and rosters (p<0.0001). Permanent night workers had the highest social jetlag (5:08h) and latest mid-sleeps on workdays and free days. Sleep quality was reduced in permanent night shift workers compared with shift workers in other rosters and differed between daytime and nighttime sleep.

Conclusions
Shift work leads to partial sleep deprivation, which particularly affects workers in 12h-shifts and permanent night shifts. Working these shifts resulted in higher sleep debts and larger absolute social jetlag whereas sleep quality was especially reduced in permanent night shift workers compared with shift workers of other rosters.
Functional MRI-based study of emotional experience in patients with psychogenic non-epileptic seizures: Protocol for an observational case-control study–EMOCRISES study
Authors: Fauvé Pierre , Tyvaert Louise , Husson Cyril , Hologne Emmanuelle , Gao Xiaoqing , Maillard Louis , Schwan Raymund , Banasiak Claire , El–Hage Wissam , Hossu Gabriela , Hingray Coraline 
Published: January 2022

Background
Psychogenic non epileptic seizures (PNES) are a frequent, disabling and costly disorder for which there is no consensual caring. They are considered as a dissociative disorder and they share many common characteristics with post-traumatic stress disorder (PTSD). Nevertheless, their pathophysiology is still unclear. In this study, we plan to obtain new data comparing functional brain activity of participants suffering from PNES, from PTSD and healthy controls via functional brain MRI during resting state and under emotional visual stimulation. The protocol presented hereunder describes an observational study with no direct treatment implication. Nevertheless, it could lead to a better understanding of PNES and to identifying targets for specialised cares of post-traumatic or dissociative disorders, like repetitive transcranial magnetic stimulation.

Methods & analysis
This is a prospective, single-centre, interventional, non-randomized, open, controlled and exploratory clinical study. It will involve 75 adult French, right-handed women in 3 groups, either suffering from PNES or PTSD, or healthy controls. An informed consent will be signed by each participant. All of them will be given psychiatric tests to assess dissociation and alexithymia, psychopathological profile and history, and emotional recognition. Each participant will undergo a functional brain MRI. We will record anatomical images and five functional imaging sequences including emotional periodic oscillatory stimulation, standard emotional stimulation, Go / No Go task under emotional stimulation, and resting state. Analysis will include a descriptive analysis of all participants and the treatment for functional magnetic resonance imaging images of each sequence.

Registration, ethics & dissemination
This study was approved the regional Protection of Persons Committee under the reference 16.10.01 and by the French National Medical Security Agency under the reference 2016-A01295-46. The protocol and results will be published in peer-reviewed academic medical journals and disseminated to research teams, databases, specialised media and concerned patients’ organisations.
Quantile-specific heritability of plasma fibrinogen concentrations
Authors: Williams Paul T. 
Published: January 2022

BackgroundFibrinogen is a moderately heritable blood protein showing different genetic effects by sex, race, smoking status, pollution exposure, and disease status. These interactions may be explained in part by “quantile-dependent expressivity”, where the effect size of a genetic variant depends upon whether the phenotype (e.g. plasma fibrinogen concentration) is high or low relative to its distribution.PurposeDetermine whether fibrinogen heritability (h2) is quantile-specific, and whether quantile-specifich2could account for fibrinogen gene-environment interactions.MethodsPlasma fibrinogen concentrations from 5689 offspring-parent pairs and 1932 sibships from the Framingham Heart Study were analyzed. Quantile-specific heritability from offspring-parent (βOP,h2= 2βOP/(1+rspouse)) and full-sib regression slopes (βFS,h2= {(1+8rspouseβFS)0.05–1}/(2rspouse)) were robustly estimated by quantile regression with nonparametric significance assigned from 1000 bootstrap samples.ResultsQuantile-specifich2(±SE) increased with increasing percentiles of the offspring’s age- and sex-adjusted fibrinogen distribution when estimated from βOP(Ptrend= 5.5x10-6): 0.30±0.05 at the 10th, 0.37±0.04 at the 25th, 0.48±0.05 at the 50th, 0.61±0.06 at the 75th, and 0.65±0.08 at the 90thpercentile, and when estimated from βFS(Ptrend= 0.008): 0.28±0.04 at the 10th, 0.31±0.04 at the 25th, 0.36±0.03 at the 50th, 0.41±0.05 at the 75th, and 0.50±0.06 at the 90thpercentile. The larger genetic effect at higher average fibrinogen concentrations may contribute to fibrinogen’s greater heritability in women than men and in Blacks than Whites, and greater increase from smoking and air pollution for theFGB-455G>A A-allele. It may also explain greater fibrinogen differences between: 1)FGB-455G>A genotypes during acute phase reactions than usual conditions, 2)GTSM1and IL-6-572C>G genotypes in smokers than nonsmokers, 3)FGB-148C>T genotypes in untreated than treated diabetics, andLPL PvuIIgenotypes in macroalbuminuric than normoalbuminuric patients.ConclusionFibrinogen heritability is quantile specific, which may explain or contribute to its gene-environment interactions. The analyses do not disprove the traditional gene-environment interpretations of these examples, rather quantile-dependent expressivity provides an alternative explanation that warrants consideration.
Протестный экоактивизм в цифровой среде (на примере «Красноярского кейса»)
Authors: Расторгуев Сергей Викторович , Тян Юлия Сергеевна 
Published: January 2022

Предмет исследования настоящей статьи — протестный экоактивизм в цифровой среде на примере резонансного «Красноярского кейса». С использованием тематического моделирования методом латентного размещения Дирихле (LDA) проанализированы комментарии к постам на экологическую тематику в социальных сетях «ВКонтакте», «Одноклассники», Twitter, Facebook, Instagram за период 1 января 2021 г.—14 июня 2021 г. Выделены шесть ключевых тем, две из которых идентифицированы как наиболее протестные. Эти две протестные темы обусловлены негативными экстерналиями хозяйственной деятельности предприятий, недовольством качеством политического менеджмента государственных органов.
«Красноярский кейс» протестного онлайн экоактивизма исследован по региональным эко-сообществам «ВКонтакте» с использованием информационно-аналитической системы «Медиалогия». Анализ офлайн активности митингующих и данных вовлеченности пользователей эко-сообществ «ВКонтакте» по «Красноярскому кейсу» не позволяет утверждать, что существует прямая зависимость между высокой вовлеченностью и большим количеством митингующих. Авторы пришли к выводу о ситуативном, контекстном характере офлайн-протестов. Цифровое участие в кейсе лидеров общественного мнения способствует привлечению внимания широкой интернет-аудитории и рассмотрению локальной ситуации как части национальной или мировой повестки.
Предложенный авторами индекс протестного экоактивизма позволяет произвести скоринг конкретного кейса на основе критериев локализации, интенсивности, политизации, текущего статуса ситуации и потенциала конфликтности. Ранг индекса дает информацию ключевым стейкхолдерам в лице общества, бизнеса, государства о текущем положении и потенциальных вариантах развития событий для принятия стратегических и тактических решений.
Pád karierního systému pro pedagogické pracovníky v roce 2017 – případová studie vzdělávací politiky
Authors: Michek Stanislav , Spilková Vladimíra 
Published: January 2022

Cíle: Cílem případové studie vzdělávací politiky je přispět k poznání a porozumění fenoménu nepřijetí karierního systému pro pedagogické pracovníky v roce 2017 v širším kontextu přístupů vzdělávací politiky k učitelské profesi po roce 1989. Uvedený případ demonstruje silné a slabé stránky vzdělávací politiky realizované v průběhu posledních let.
Metody: K získání odpovědí na hlavní výzkumné otázky - (1) V čem byly hlavní příčiny nepřijetí karierního systému v roce 2017? (2) Jaká byla role klíčových aktérů v procesu ne/přijetí? - byly využity metody kvalitativního výzkumu, zejména analýza dokumentace z jednání Poslanecké sněmovny a Senátu ČR, analýzy masmédií, polostrukturované rozhovory s klíčovými aktéry procesu schvalování a zamítnutí karierního systému.
Výsledky: Jsou popsány procesy komunikace a interakce klíčových aktérů vzdělávací politiky a vliv nového subjektu (Pedagogická komora), který se v situaci atomizace profesní komunity do mnoha asociací, zájmových a vlivových skupin stává hlasitým, organizovaným hlasem reprezentujícím populistické postoje učitelské veřejnosti. Dále jsou analyzovány ne/schopnost komunikace ministerstva se zástupci školské praxe a s „opinion makery“, míra politizace v rozhodování, věcná znalost a porozumění politiků odborným otázkám, vliv odborníků a expertních názorů v politickém rozhodování o odborných otázkách řízení školství, vliv sociálních sítí při ovlivňování veřejného mínění apod.
Diskuze výsledků a závěry: Je reflektován fenomén „krize expertnosti“ (Nichols, 2017) – trend k ignorování expertních znalostí a výzkumně doložených dat, mizí dialog mezi experty a širší veřejnosti, zesílení jisté formy politické korektnosti, kdy všechny názory jsou považovány za stejně hodnotné, každý názor musí zaznít apod. Součástí tohoto trendu ve veřejném rozhodování je vzestup „agresivní nevědomosti“ chápané jako lpění na vlastním názoru i tváří v tvář protiřečícím faktům. Agresivní nevědomost posilují sociální sítě. Výzkum otevírá řadu otázek věcných, metodologických i etických. Studie nastiňuje příležitosti a rizika české vzdělávací politiky v kontextu dalších aktivit ovlivňujících de/profesionalizaci učitelské profese v ČR.
Results of the surgical treatment of diffuse pigmented villonodular synovitis (diffuse-type tenosynovial giant-cell tumor) of the knee
Authors: Herasymenko S. I. , Kostogryz O. A. , Kostogryz Yu. O. , Babko A. M. , Mayko V. M. 
Published: January 2022

The aim. To develop a treatment algorithm with the aim of improving the treatment results of diffuse pigmented villonodular synovitis of the knee. To study and analyze the results of surgical treatment of diffuse pigmented villonodular synovitis of the knee.
Materials and methods. The study was based on the results of treatment of 48 patients with pathohistologically verified diagnosis of diffuse pigmented villonodular synovitis (tenosynovial giant cell tumor) of the knee undergoing treatment at the State Institution “Institute of Traumatology and Orthopedics of the National Academy of Medical Sciences of Ukraine” from 2010 to 2019.
Results. The best functional results can be achieved in patients with diffuse pigmented villonodular synovitis of the knee in stage I of the disease. Using the method of mathematical statistics to evaluate the results obtained, we see that scores obtained through the Lysholm Scoring Scale were statistically significantly different in stages before a surgery (P = 0.000782), 3 months (P = 0.00005) and 6 months after the surgery (P = 0.04); but over time, these differences diminished and became actually insignificant 12 months after the surgery (P = 0.89).
Conclusions. Applying our therapeutic algorithm for the treatment of patients with diffuse pigmented villonodular synovitis of the knee, the outcome of the Lysholm score was excellent in 22 % of patients, good – in 45 %, satisfactory – in 21 % and poor – in 12 % of patients.
Entrepreneurs’ Networking Styles and Normative Underpinnings during Institutional Transition
Authors: Zhang Chenjian , Wang Tao , Ahlstrom David 
Published: January 2022

Abstract
Existing network research has mainly adopted functional and/or structural approaches to study the instrumental goals behind entrepreneurs’ networking as well as the influence of personal position on access to resources and eventual performance. The variety of entrepreneurs’ networking styles and their normative underpinnings have not been adequately explored. Contextualized in China, this study asks: How do entrepreneurs’ understandings of social norms shape their networking styles? Through an inductive comparison of two entrepreneur generations in China, we identify three networking styles: guanxi-oriented networking, market-based networking, and mixed networking. We theorize that three types of norms shape these styles: market-inferred norms, dyadically formed norms, and identity-induced norms. This study provides new insights into the understanding of Chinese entrepreneurs’ distinctive networking styles and their normative underpinnings. Further, it suggests implications both for the wider study of entrepreneurs’ networking behaviors in transition economies, and for practitioners wishing to enhance their network building in China.
Evaluation of thickened liquid viscoelasticity for a swallowing process using an inclined flow channel instrument
Authors: Yoshida Masanori , Tsuruta Yuko , Takako Yuichiro , Kudo Ayaka , Fujiwara Ryosuke 
Published: January 2022

Abstract
An inclined flow channel instrument that can be developed to be a structurally simple and easy-to-use rheometer was applied to control the thickness, specifically the viscosity and elasticity, of liquids thickened to support swallowing in nursing-care practice. Aqueous solutions containing salt or acid, which might be used as ingredients in drinks, were thickened with a commercial thickener. The thickener efficacy decreased because of the salt or acid in liquid phase. Analysis of the flows in the instrument by experimentation yielded a dimensionless relation representing changes of the Deborah number in the flow process, as indicated by the relative flow length, considering the shear rate in oral processing. One unique methodology to evaluate the viscoelasticities of thickened liquids during the swallowing process was presented utilizing the measurements such as elapsed time and velocity in the instrument.
Forschungsdatenmanagement als Arbeitsschwerpunkt für Informationswissenschaftler/innen
Authors: Zeunert Miriam , Schneemann Carsten 
Published: January 2022

Zusammenfassung
Forschungsdatenmanagement ist ein informationswissenschaftliches Thema, das kontinuierlich an Bedeutung gewinnt. Zur Abgrenzung von Arbeitsschwerpunkten für Informationswissenschaftler/innen wurde ein aktuelles Stellenanzeigenkorpus mit Bezug zum Forschungsdatenmanagement (FDM) ausgewertet und in einem erweiterten Forschungsdatenlebenszyklus verortet. Dieser Praxisrepräsentation wurde eine Literaturanalyse gegenübergestellt. Die abschließende Zusammenführung und Auswertung innerhalb des Forschungsdatenlebenszyklus zeigt eine hohe Kongruenz der Schwerpunktverteilung zwischen Theorie und Praxis.
Diabetic wound healing approaches: an update
Authors: Keni Raghuvir , Begum Farmiza , Gourishetti Karthik , Viswanatha Gollapalle Lakshminarayanashastry , Nayak Pawan Ganesh , Nandakumar Krishnadas , Shenoy Rekha R 
Published: January 2022

Abstract
Diabetic wounds are of profound clinical importance. Despite immense efforts directed towards its management, it results in the development of amputations, following a diagnosis of diabetic foot. With a better understanding of the complexities of the microbalance involved in the healing process, researchers have developed advanced methods for the management of wounds as well as diagnostic tools (especially, for wound infections) to be delivered to clinics sooner. In this review, we address the newer developments that hope to drive the transition from bench to bedside in the coming decade.