bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of factors that impact the production of anti-SARS-CoV-2 antibodies in patients with COVID-19
Authors: Hussein Nawfal R , Balatay Amer , Mohammad Ameen M , Dhama Kuldeep , Rasheed Narin A 
Published: October 2022

Objectives: The aim of this paper was to investigate the impact of different variables on the production of antibodies in patients who were infected with Covid-19.
Methods: This cross-sectional study was conducted in Duhok City, Kurdistan Region of Iraq. The study was conducted between January 2021 and March 2022. Demographic data were collected via face-to-face interview. Antibody levels were determined using Elecsys Anti-SARS-CoV-2.
Results: The levels of antibody were studied in 138 patients. A significant association was found between antibody levels and the age of the participants (r=0.175; P=0.04). Besides, a significant correlation was found between antibody levels and the duration of symptoms (r=0.206; P=0.015). The antibody levels were not associated with gender; history of chronic diseases; marital status or time interval before testing.
Conclusions: Different variables that may impact the levels of antibody were studied. Significant associations were found between antibody levels and both age and duration of symptoms. Our results can be used by healthcare providers to focus on patients who are at risk of low antibody production.
Explaining the conceptual considerations of virtual university in medical education: a systematic review
Authors: Ahmady Soleiman , Habibi Amin , Koshgoftar Zohreh 
Published: October 2022

Aim: Most of existing literature on the concept of virtual university of medical sciences have been collected in a non-systematic manner. This issue highlights the need to conduct research on virtual university-related topics through systematic research evidence and empirical evaluations. The aim of the present study is to investigate the real complexity and diversity of the concept of virtual university of medical sciences.
Method: This was a systematic review with the BeHEMoTH approach and aimed to identify, review, analyze and integrate models, theories and frameworks related to the concept of virtual university of medical sciences. Eligible articles were searched in PubMed, ERIC, IEEE، ISI ،Scopus, Ecampus research unit from 2001 to 2022 using related keywords in three stages.
Results: A total of 13 articles were finally identified according to inclusion and exclusion criteria. Pedagogical, technology, managerial, educational design, technology implementation, and educational-administrative management components were referred to in 5, 5, 4, 7, 6 and 4 articles, respectively. Thematic analysis of the models was carried out in two theoretical dimensions (pedagogical component, managerial component and technological component) and operational dimension (educational design, administrative-educational management and technology implementation).
Conclusion: The results of the present study emphasize the need to pay attention to these six components in the establishment and development of virtual universities of medical sciences. In order to improve the education process in virtual universities, the process quality evaluation framework can be used.
Development of dental specialties in Iran: A qualitative study
Authors: Rojhanian Tayebe , Jadidfard Mohammad Pooyan , Yazdani Shahram 
Published: October 2022

Objectives: Dental specialties in Iran were first established in 1970s, and developed over time. Considering that information is essential for health policymaking, and lack of it is the main problem; therefore, policymakers require adequate knowledge about development and alterations of healthcare providers to recognize the influential factors on them. Regarding the information gap on development of dental specialties in Iran, this qualitative study aimed to assess it.
Methods: This qualitative case study was conducted through 12 semi-structured interviews with the experts and pioneers of the oral healthcare system in Iran who were selected by purposive and snowball sampling. Data were analyzed by content analysis method, which included transcribing, identifying the meaning units, abstracting the content, sorting codes, and formulating themes using Atlas.ti software.
Results: After data analysis, three main themes were extracted regarding development of dental specialties in Iran according to the interviewees: (A) trend of development, (B) challenges of development, and (C) necessities of development. Trend of development of dental specialties included two comprehensive phases, and one phase focusing on quantity and inadequate attention to quality. The challenges of development of dental specialties included management and policy-making problems, interactions outside the system, popularity of specialization, and process of admission to specialty programs. The necessity of need assessment, paying attention to the costs of healthcare interventions, defining the range of specialization, and revision of dental specialty programs are among the necessities of development of dental specialties.
Conclusion: Dental specialties in Iran were developed at a time with inadequate attention to shortage of infrastructure based on political interactions. The popularity of specialization in dentistry and the associated high costs in a free educational system highlight the significance of need assessment regarding the number of specialists required in academic and therapeutic fields, and setting some criteria for development of specialty programs.
Docking study, Synthesis, Characterization and Preliminary cytotoxic evaluation of new 1,2,3,4-tetrahydroppyrimidine derivatives
Authors: Mohammed Noor M. 
Published: October 2022

Objective: This study resolved that1 these anew synthesized analogs1 may 1be embodied as1 an 1exploitable foundation of new 1anticancer1 1agents to competition breast 1cancer
Methods: By means of The crystal1 structure of Histone deacetylases (HDACs-8) with Vorinostat (SAHA) as 1a co-crystalized1 ligand 1was gained1 from 1the protein 1data-bank 1 (PDB 1code 4QA0) as a result 1of 1docking the compounds (V a,s, V b,s, V a,t and V b,t) give 1good docking 1scores compared1 to the standard. 1 Compounds (V a,s, V b,s, V a,t and V b,t) was synthesized1 by multistep procedures1 from the reaction of intermediate derivatives (IV a,b) and the thiosemicarbazide or semicarbazide . The chemical1 structures1 of the1 target compounds11 and 1their intermediates1 were1 confirmed by 1FT-IR and1H 1NMR
Results: The in-vitro cytotoxicity1 assay (MTT assay) demonstrated1 that compounds1 V a,t and V b,t showed1 good inhibition 1ratios in Breast1 cancer cell line1 (MCF-7) and human colon adenocarcinoma (HRT-18) 1comparable with drug1 control Vorinostat (SAHA).
Conclusion: 1From the docking1 study, it was1 concluded1 that C=S moiety were very1 1successful to bind 1tightly to the zinc binding group of HDAC enzyme by making numerous 1interaction modes.
Evaluation of the hemoglobin level in gingival crevice fluid and clinical periodontal parameters in patients with chronic periodontitis
Authors: Taheri Sina , Samadaei Mahdis , Pakkhesal Mina , Ahmadinia Amir Reza 
Published: October 2022

Objectives: The present study aimed to evaluate the level of hemoglobin in gingival crevicular fluid (GCF) and its relationship with clinical periodontal parameters in chronic periodontitis.Methods: This cross-sectional study was conducted in patients with chronic periodontitis. Gingival crevicular fluid was sampled and clinical periodontal parameters PI, PPD, CAL, and BOP were measured. The level of hemoglobin in GCF was measured using a hemoglobin kit. Data were analyzed using Spearman's correlation test and Mann-Whitney's test in Stata 14.1 software.
Results: 315 teeth from patients with chronic periodontitis were evaluated. There was a strong and direct correlation between the amount of GCF hemoglobin and the amount of PPD, CAL and PI, their correlation coefficient was equal to 0.78, 0.88 and 0.82, respectively (P<0.001). The mean hemoglobin GCF in the positive BOP group was 68.84 ± 30.89 and in the negative BOP group was 59.28 ± 8.03, which showed a significant difference in the average hemoglobin between the two groups (P<0.001).
Conclusion: According to the findings of this study, there is a strong correlation between periodontal clinical parameters and the level of GCF hemoglobin, and measuring the level of hemoglobin in the gingival crevice fluid can be an accurate measure and a non-invasive method for investigating periodontal conditions.
Model Pembelajaran Aktif Berbantuan Media Fun Thinkers Terhadap Hasil Belajar Siswa Sekolah Dasar
Authors: Putri Ni Putu Ikka , I Gusti Ayu Tri Agustiana  , Alexander Hamonangan Simamora  
Published: October 2022

Pendekatan belajar modern menyebutkan bahwa siswa sebagai subjek belajar dan guru sebagai fasilitator yang nantinya akan memberikan kemudahan pada siswa dalam melaksanakan aktivitas kegiatan belajar. Guru yang kurang memperhatikan model ataupun media pembelajaran yang digunakan sehingga berdampak pada hasil belajar siswa rendah. Penelitian ini bertujuan untuk menganalisis model pembelajaran aktif berbantuan media Fun Thinkers Terhadap hasil belajar siswa kelas I sekolah dasar. Jenis penelitian ini yaitu eksperimen semu (quasi eksperimen) dengan rancangan non-equivalent post-test only control group design. Populasi berjumlah 91 siswa. Penelitian menggunakan teknik pengambilan random sampling. Sampel penelitian ini berjumlah 37 siswa. Metode mengumpulkan data yaitu tes. Instrument yang digunakan yaitu lembar tes uraian. Teknik yang digunakan untuk menganalisis data yaitu statistik deskriptif dan statistik inferensial. Hasil penelitian yaitu terdapat pengaruh yang signifikan model Pembelajaran Aktif Berbantuan Media Fun Thinkers terhadap hasil belajar siswa kelas I SD. Disimpulkan model Pembelajaran Aktif Berbantuan Media Fun Thinkers dapat meningkatkan hasil belajar siswa
Herramientas learning como medio de apoyo en la disminución de la reprobación en la Universidad Autónoma del Carmen para la modalidad a distancia
Authors: Barradas Arenas Ulises Daniel , Cocón Juárez José Felipe 
Published: October 2022

De acuerdo con datos estadísticos, en la Facultad de Ciencias de la Información 40 % de los estudiantes abandona por casos de deserción y 30 % por rezago escolar, lo cual ocurre durante el primer año escolar debido a reprobación de materias. El modelo Acalán de educación a distancia basado en el constructivismo plantea estrategias de apoyo contra la reprobación, pero estas no son suficientes. Por eso, esta investigación tiene como objetivo evaluar el impacto de un repositorio de herramientas de aprendizaje e-learning y las estrategias didácticas aplicadas para disminuir la reprobación en la licenciatura en Tecnologías de la Información de la Universidad Autónoma del Carmen. En concreto, se utilizaron tres instrumentos con los cuales se validó la viabilidad de la propuesta, que incluyó los objetos de aprendizaje necesarios para integrarlos en el repositorio, para lo cual se midieron las necesidades de estudiantes y profesores. La metodología usada se apoyó en una muestra de 17 alumnos regulares, 10 irregulares y tres profesores que trabajaron en un curso de programación con apoyo del repositorio. Como resultado se obtuvo que de los alumnos inscritos en el curso solo 29 % reprobara la asignatura. Asimismo, la aplicación del modelo de regresión lineal y Anova mostró que las variables falta de interés y mayor calidad en los contenidos son factores que impactan en la reprobación. En síntesis, se recomienda un entrecruzamiento con la carrera de Ingeniería en Diseño Multimedia para la elaboración de materiales de alta calidad que permitan evaluar las herramientas de trabajo e-learning idóneas para un mejor desempeño por parte de los docentes en las unidades didácticas.
Analisis In Silico Naringenin dari Umbi Akar Batu (Gerrardanthus macrorhizus Harv.ex Benth. & Hook.f.) sebagai Antitusif terhadap Reseptor N-methyl-D-aspartate
Authors: Maria Angelina Genere Koban  , Sri Rahayu Lestari  , Frida Kunti Setiowati  
Published: October 2022

Batuk merupakan refleks pertahanan tubuh alami yang membersihkan saluran pernapasan dari benda asing. Dekstrometorfan merupakan obat antitusif yang bersifat antagonis non-competitive chanel blocker terhadap reseptor N-Methyl-D-aspartate yang mampu menekan batuk di pusat ambang batuk. Penelitian ini bertujuan untuk menganalisis potensi naringenin sebagai antitusif berdasarkan nilai afinitas pengikatannya dengan reseptor NMDA, sifat farmakokinetik, potensi biooral dan toksisitas melalui pendekatan in silico dengan teknik molecular docking. Hasil penelitian menunjukkan, bahwa dekstrometorfan dan naringenin berikatan di residu asam amino yang sama dengan NMDA pada MET A: 145, ILE A: 85, ALA B: 888 dengan ikatan hidrofobik, SER A: 81 dengan ikatan hidrogen pada dekstrometorfan dan ikatan unfavorabel donor-donor pada naringenin. Nilai binding affinitas naringenin -6,7 kkal/mol lebih kecil dibandingkan dengan dekstrometorfan -6,4 kkal/mol, hal ini menunjukkan bahwa naringenin berpotensi sebagai antitusif yang hampir sama dengan dekstrometorfan. Hasil uji toksisitas, menunjukan bahwa naringenin dan dekstrometorfan dapat dikonsumsi secara oral dan tidak berbahaya bagi kesehatan. Analisis potensi bioral dan uji farmakokinetik membuktikan bahwa naringenin mampu diabsorbsi, didistribusi, dimetabolisme dan diekskresi, sehingga berpotensi sebagai kandidat obat antitusif.
GRADUATION DALAM PANYANDRA PANGGIH PERNIKAHAN ADAT YOGYAKARTA
Authors: Annisa Ifriani 
Published: October 2022

Pesan dapat disampaikan dalam berbagai moda. Moda tersebut dapat berbentuk tulisan, lisan atau verbal, gambar, atau campuran. Penelitian ini menggunakan moda verbal dan tulisan pada suatu teks. Teks yang digunakan dalam penelitian ini adalah teks panyandra panggih pernikahan adat Yogyakarta. Pada teks ditemukan beberapa penekanan atas ekspresi emotif yang disampaikan oleh pembawa acara (pranatacara). Penekanan ekspresi emotif dapat memberikan gambaran mengenai sikap pihak-pihak yang terkait dalam acara panggih. Penelitian ini bertujuan untuk menelaah penekanan ekspresi emotif yang terdapat pada teks panyandra panggih. Adapun masalah penelitian yang diangkat adalah bagaimana ekspresi emotif ditegaskan dalam teks. Teori yang digunakan adalah bagian dari teori appraisal (Martin dan White, 2005) yaitu graduation. Appraisal berfokus pada ekspresi emotif yang terdapat pada suatu wacana atau teks. Hasil penelitian ini menunjukkan terdapat dua macam penekanan yaitu leksikalisasi dan repetisi. Kekhasan pada penekanan ekspresi emotif dalam bahasa Jawa pada teks adalah leksikalisasi. Leksikalisasi yang terdapat pada teks termasuk pada tembung saroja pada bahasa Jawa. Penelitian ini diharapkan dapat menambah wawasan terkait bahasa dan kebudayaan Jawa. Selain itu, penelitian ini juga diharapkan dapat berkontribusi untuk bidang linguistik khususnya teori appraisal yang dapat diaplikasikan pada teks berbahasa Jawa.
Analisis Statistika dalam Riset-Riset Psikologi Komunikasi: Sebuah Studi Literatur
Authors: Santoso Agung 
Published: October 2022

The increasing number of studies in psychology on communication demanded the use of more relevant statistical analysis techniques that can meet the needs for these studies. Conventional analysis techniques, such as ones that were based on linear model, assume that the observation are independent. Such assumption were often violated in studies on communication. Therefore, it was imperative to develop statistical analysis techniques that could address problems related to data with dependent observation either in communication events. Such efforts could not be separated from literature studies addressing several research questions: (1) What kind of research questions that frequently arose in communication in Psychology?, (2) What statistical analysis techniques that were commonly used to answer the questions in such studies?, (3) What potential statitical analysis techniques that could be used in the studies?, and (4) How were the discrepancies between the needs in communication studies in Psychology with the statistical analysis techniques currently available? The current studies attempted to address those questions by conducting a study of literature review. It was shown that there was still a big space for improvement for studies on communication particularly in Indonesia. Many statistical techniques that were currently available, such as dyadic analysis or social network analysis, have not been employed to address the issues related to dependence of observation or social relations data. Moreover, statistical models or techniques should be developed to measure communication events to reduce the dependence on self-report assessments.
Analysis and design of scalable pre-processing techniques of instances for imbalanced Big Data problems. Applications in humanitarian emergencies situations.
Authors: Basgall María José 
Published: October 2022

This thesis addresses the distributed and scalable pre-processing of Big Data sets, in order to obtain good quality data, known as Smart Data. Particularly, it focuses on classification problems, and on addressing the following characteristics: (a) imbalanced data; (b) redundancy; (c) high dimensionality; and (d) overlapping.The following specific objectives are established for the aforementioned purpose:

Enable a state-of-the-art algorithm widely used for the treatment of class imbalance in traditional data scenarios (Small Data), to be able to obtain adequate results from large datasets in a distributed manner and in reasonable execution times.
To design and to implement a fast and scalable methodology for the reduction in both instances and attributes for Big Data sets with high redundancy and dimensionality, while maintaining the predictive capacity of the original dataset.
To design and to implement a strategy for scalable data characterisation in the context of Big Data classification, focusing on the ambiguous areas of the problem.
To apply the knowledge acquired during the development phase to solve problems of interest related to humanitarian emergencies.
Covid-19 pandemic: Psychosocial effect among physical and health education staff in Kogi State Nigeria
Authors: Olowoleni Victor , Ayodele Kolade Babatunde , Olaseyo Toyosi , Adeola Moses Folusayo 
Published: October 2022

Fear and anxiety have always been a negative affect in performance and job settings, especially when there are external pressures. The Corona virus-19, took the world by surprise just when everybody was enthusiastic about the long-expected year 2020. Movements were restricted, offices, businesses, and public places shut down with imposed curfews allowing only “essential workers” do their jobs. These, invariably affected the way work and associations would later become even after the lockdown. The study aimed to know whether the psychosocial effect of COVID-19 (fear and anxiety) affect physical and health education staff of Kogi State Nigeria. Descriptive survey method was adopted for the research. 200 respondents (male & female) that included physical and health education staff (350) from all higher institutions in Kogi state were part of the study. The average age of respondents was 48.5years. The Fear of COVID-19 Scale (FCV-19S) (α =.74) and the Corona Virus Anxiety Scale (α =.82) was used to collect data. Descriptive statistics of frequency counts, means and percentages were used to analyze data. It is concluded that physical and health education staff in Kogi State do not experience anxiety and fear due to COVID-19. A limitation encountered was most respondents feared been stigmatized with COVID as was the case at the time. It is significant in the sense that employees are greatly influenced by the views of their employer. Further research should be on the attitude of physical and health educators in Kogi State Nigeria to work during COVID-19 pandemic.
گوهورینا دیروكى یا ڤاولێن زمانێ كوردی
Authors: Ahmed Mezgin A. 
Published: October 2022

ئه‌ڤ لێكولینه‌ ب ناڤ و نیشانێ (گوهورینا دیروكی یا ڤاولێن زمانێ كوردى) ئاسته‌كێ گرنك یێ زمانى كو فۆنۆلۆجییه‌ دئێخیته‌ بن لێكولینێ، شێوازێ لێكولینێ، وه‌سفى، شیكارى و دیروكى یه‌ كو تێدا قوناغێن گوهورینا ڤاولێن زمانێ كوردى د سه‌رده‌مێن كه‌ڤنار هه‌تا كوردىیا نها رووهن دكه‌ت.
ئه‌ڤ لێكولینه‌، ل پێشه‌كیه‌ك و چه‌ند ته‌وه‌ره‌كا پێك دهێت ئه‌و ژى:
هوكارێن گوهورینا زمانى(كو تێدا ئه‌و هوكارێن سه‌ره‌كى وگرنگ بو گوهورینا زمانان ده‌ستنیشان دكه‌ت).
ئارمانجێن گوهورینا زمانى(ده‌ره‌نجام و ئه‌و ئارمانجێن كو هه‌ر زمانه‌كى بو ڤان گوهرینان هه‌یه‌ دیار دكه‌ت).
یاسایێن گوهورینا ده‌نگان(ئه‌و ژى یاسایێن فۆنۆلۆجى و چه‌واى یا هه‌لویستا ڤان یاسایان د كوردیدا ده‌ردئێخیت).
پاشى د ته‌وه‌ره‌كا دى دا، دچیته‌ سه‌ر كاكلا ڤێ لێكولینێ ئه‌و ژى لێكولینه‌ ل گوهورینا دیروكیا (7) ڤاولێن زمانێ كوردى و سمتا دیروكیا ڤان گوهورینان د زمانێن هندوئه‌وروپى هه‌تا كوردیا نها دا. د دوماهیكێدا ب ئه‌نجامه‌كێ لێكولین ته‌مام دبیت و ئه‌نجام ژى ب ده‌رخستنا خشته‌كێ گوهورینا ڤاولێن كه‌ڤنار بو كوردیا نها رووهن دكه‌ت. و هه‌روه‌ها به‌حسى به‌رده‌وامیا ڤان گوهورینا دكه‌ت كو نها ژى د دیالێكتێن كوردیدا هه‌ست پێ دهێته‌كرن.
مفهوم العدالة وضوابطها عند المحدثين
Authors: Al - Warmili First A. 
Published: October 2022

يتناول هذا البحث دراسة شرط من شروط صحة الحديث النبوي ألاّ وهو شرط العدالة في رواة الحديث، فالعدالة شرط لقبول الرواية وصحتها عند جماهير أهل العلم بالحديث والفقه والأصول؛ لأنها ملكة عند المرء تحمله على ملازمة التقوى واجتناب المحظور، فمن لم يكن على هذه الصفة يجب عدم السماع منه والعدول عنه، حيث أجمع العلماء المسلمون قاطبة من أهل الحديث والفقه والأصول أن الراوي لا تقبل روايته إلا إذا اجتمعت فيه صفتان (العدالة، والضبط).
فالبحث يبين مفهوم العدالة عند المحدثين وشروطها، والأمور التي تثبت بها عدالة الراوي وما تخل بها، كما يلقي البحث الضوء على ضوابط العدالة عند المحدثين من خلال بيان هل يثبت التعديل بقول معدل واحد؟ وبيان مراتب التعديل وحكم هذه المراتب، واختلاف علماء الحديث في تعديل المرأة والصبي، ويبين البحث أقوال العلماء في اجتماع الجرح والتعديل في راوٍ واحد وأيهما يقدم في هذه الحالة، كما يبين الفرق بين العدالة في الراوية والشهادة.
Intervención didáctica para minimizar la ciber victimización de adolescentes
Authors: Haz Lídice , Dávila Araceli , Domínguez Mariela , Gabriela Campuzano María 
Published: October 2022

Los avances tecnológicos en los últimos años han contribuido a grandes cambios sociológicos. La globalización y los cambios en los diferentes ámbitos de la comunicación han propiciado una temprana adopción de las tecnologías de la información y la comunicación (TIC). Esta situación, conlleva a que los usuarios especialmente menores de edad se expongan a riesgos y amenazas derivados del mal uso de las TIC y el internet. La victimización en entornos virtuales es más evidente en menores de edad quienes sufren una violencia silenciada pero con consecuencias psicológicas graves. Es importante conocer y hacer visible este fenómeno para saber cómo abordarlo. El objetivo de este trabajo es describir las características y las consecuencias de las diferentes formas de victimización en entornos virtuales, tales como grooming, sexting y ciberbullying. También, se presentan algunos mecanismos de prevención para mitigar estos tipos de acosos; además, se detalla la propuesta de un programa de formación académica en seguridad informática dirigida a menores de edad, con la finalidad de que aprendan a utilizar y convivir de manera adecuada en los entornos virtuales generando mayor interés, conciencia y reflexión sobre los riesgos presentes en estos medios.