bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-stabilization of levitating droplet clusters: A new idea and its experimental confirmation
Authors: Dombrovsky Leonid , Fedorets Alexander , Levashov Vladimir , Shcherbakov Dmitry 
Published: February 2022

Abstract
A method of self-stabilization of a droplet cluster levitating over the locally heated water surface is proposed for the first time. The physical analysis of the problem shows that the desired result can be reached by dissolving a small amount of sodium chloride in a layer of water. This is explained by simultaneous action of two processes with opposite effects on evaporation. On the one hand, when water evaporates, a thin layer of increased salt concentration that prevents evaporation is formed at its surface. On the contrary, diffusion of salt in water decreases the surface concentration of salt. Different combinations of water heating intensity and average salt concentration are expected to result in the stable size of nearly identical levitating droplets, when there is a balance between the droplet evaporation and the condensation of vapor from the ascending vapor-air flow. The predicted phenomenon has been observed experimentally. In a series of laboratory experiments, a range of parameters has been obtained for which self-stabilization of the droplet cluster takes place. An analysis of the combined problem of heat transfer, water evaporation, and salt diffusion in water made it possible to obtain the minimum required value of the salt concentration, which is very close to that obtained experimentally.
Do Physical Activity and COVID-19-Related Anxiety Affect Eating Disorders? Eating disordes and physical activity
Authors: Ahmadabadi Somayeh , Sedaghati parisa 
Published: February 2022

Abstract
Background

Eating disorder is one of the most common disorders among adolescents and young females. The present study aimed to investigate the relationship between eating disorders (nutrition attitude) with nutrition knowledge, physical activity level, and COVID-19-related anxiety in female students.
Methods

The present research was a correlational and causal-comparative study. The statistical population consisted of all female students of Farhangian University of Mashhad (1500 students) in 2021, of whom 247 students were randomly selected. Out of whom, 107 students were active and 140 inactive. Nutrition knowledge, eating disorder, COVID-19-related anxiety, physical activity level, and health-related anthropometric parameters were assessed via the online survey. Statistical analysis was performed using the Kolmogorov-Smirnov test, independent t-test, Pearson correlation, and linear regression in SPSS software.
Results

The results showed that there was a significant difference between active and inactive students in nutrition knowledge (P=0.01), eating disorders (P=0.003), COVID-19-related anxiety, and physical activity level (P=0.001). Additionally, eating disorders correlated significantly with COVID-19-related anxiety and physical activity level (P=0.001). The linear regression results showed that COVID-19-related anxiety could predict eating disorders in female students (P=0.001). Despite a significant negative correlation between eating disorders and physical activity level, the regression model showed that the latter could not predict the former in female students (P>0.05).
Conclusion

According to the results, it can be said that in certain conditions, such as the COVID-19 pandemic, increased anxiety levels can increase the prevalence of eating disorders. It seems that regular physical activity can indirectly reduce eating disorders by alleviating anxiety levels.
Effectiveness of a targeted telephone-based case-management service on activity in an Emergency Department in the UK: a pragmatic difference-in-differences evaluation
Authors: Elston Julian , Gradinger Felix P. , Streeter Adam J. , Macey Stephen , Martin Susan 
Published: February 2022

Abstract
Background: This study evaluates the effectiveness of a targeted telephone-based case management service that aimed to reduce ED attendance amongst frequent attenders, known to disproportionately contribute to demand. Evidence on the effectiveness of these services varies.Methods: A 24-month controlled before-and-after study, following 808 patients (128 cases and 680 controls (41 were non-compliant)) who were offered the service in the first four months of operation within a UK ED department. Patients stratified as high-risk of reattending ED within 6 months by a predictive model were manually screened. Those positively reviewed were offered a non-clinical, nurse-led, telephone-based health coaching, consisting of care planning, coordination and goal setting for up to 9 months. Service effectiveness was estimated using a difference-in-difference (DiD) analysis. Incident rate of ED and Minor Injury Unit (MIU)) attendances and average length of stay in intervention recipients and controls over 12 months after receiving their service offer following ED attendance were compared, adjusting for the prior 12-month period, sex and age, to give an incidence rate ratio (IRR).Results: Intervention recipients were more likely to be female (63.3% versus 55.4%), younger (mean of 69 years versus 76 years), and have higher levels of ED activity (except for MIU) than controls. Mean rates fell between periods for all outcomes (except for MIU attendance). The Intention-to-Treat analysis indicated non-statistically significant effect of the intervention in reducing all outcomes, except for MIU attendances, with IRRs: ED attendances, 0.856 (95% CI: 0.631, 1.160); ED admissions, 0.871 (95% CI: 0.628, 1.208); Length of stay for emergency and elective admissions: 0.844 (95% CI: 0.619, 1.151) and 0.781 (95% CI: 0.420, 1.454). MIU attendance increased with an IRR: 2.638 (95% CI: 1.041, 6.680)Conclusions: Telephone-based health coaching appears to be effective in reducing ED attendances by 14-15% and admissions by 12-13%, with shorter lengths of stay, in intervention recipients over controls. Future studies need to capture outcomes beyond acute activity, and better understand how services like this provide added value.
Detection of Myocardial Dysfunction using Global longitudinal strain with Speckle-Tracking Echocardiography in Patients with vs without Rheumatoid Arthritis: A Systematic Review and Meta-analysis
Authors: Thallapally Vinay Kumar , Bansal Raahat , Thandra Abhishek , Gupta Sonia , Aurit Sarah , Pajjuru Venkat S. , Anugula Dixitha , Ahmed Aboeta , Nahas Joseph 
Published: February 2022

Abstract
Purpose

Rheumatoid arthritis (RA) is a systemic autoimmune disorder primarily involving the peripheral joints. Systemic involvement can occur, including myocardial dysfunction. Speckle tracking echocardiography (STE) is a novel diagnostic study that is recently being used to detect subclinical cardiac dysfunction. Global longitudinal strain (GLS) by STE is more sensitive than standard echocardiographic parameters to detect occult cardiac dysfunction.

Methods

A systematic search of PUBMED, EMBASE, Cochrane, and Google Scholar databases was performed to identify studies comparing the STE parameters between RA and non-RA patients.

Results

Left ventricular (LV) GLS was significantly lower in patients with RA compared to non-RA patients with a standard mean difference (SMD) of -1.09 (-1.48 to -0.70, P < 0.001). LV Global Circumferential Strain (GCS) was reported in five studies and it was found to be lower in RA patients with an SMD of -1.25 (-2.59 to -0.10; P < 0.0010). Meta-regression analysis studies failed to show any significant impact of disease duration, activity, age, sex, and BMI on LV GLS and RV GLS.

Conclusions

RA patients have lower LV GLS and LV GCS compared to controls suggesting impaired myocardial dysfunction. Further studies need to be done to delineate the importance of lower GLS in asymptomatic rheumatoid patients to guide disease management and risk factor modification in this selected population.
A Novel Feature Selection Method Based on Binary Differential Evolution and Feature Subset Correlation for Microarray Data
Authors: Xie Weidong , Chi Yuhuan , Wang Linjie , Yu Kun , Li Wei 
Published: February 2022

Abstract
Obtaining diagnostically important features from microarray data can help researchers understand diseases and study drugs. The challenges come from the high dimensionality, small sample size of the data and the high redundancy among features. To solve this problem, we propose a new hybrid feature selection method based on differential evolution algorithm. The proposed method the proposed method adopts a new binary quantization method to adapt to the characteristics of high-dimensional data, and improves the scaling factor and mutation operator to balance the global search performance and convergence speed of the algorithm. The proposed method also proposes the concept of feature subset correlation in the fitness function to ensure the low redundancy of feature subsets. The experimental results show that the proposed method is advanced and the selected features, are with low redundancy and can effectively distinguish between positive and negative samples.
Transforming Growth Factor Beta Isoforms and TGF-βR1 and TGF-βR2 Expression in Systemic Sclerosis Patients
Authors: Lomelí-Nieto José Alvaro , Muñoz-Valle José Francisco , Baños-Hernández Christian Johana , Navarro-Zarza José Eduardo , Godínez-Rubí Juliana Marisol , García-Arellano Samuel , Ramírez-Dueñas María Guadalupe , Parra-Rojas Isela , Villanueva-Pérez Arisbeth , Hernández-Bello Jorge 
Published: February 2022

Abstract
Systemic sclerosis (SSc) is characterized by chronic inflammation and fibrosis, two processes associated with transforming growth factor β (TGF-β) functions. In the present study, we investigated the expression of TGF-β isoforms in serum and the skin distribution of TGF-β and two receptors (TGF-βR1 and TGF-βR2) in SSc patients. A total of 56 SSc patients and 120 control subjects (CS) were included. The serum levels of TGF-β isoforms were quantified by immunoassay with magnetic microspheres, and the skin biopsies were processed by immunohistochemistry (IHC). The soluble levels of the three active TGF-β isoforms were lower in SSc patients than in CS (p < 0.0001). However, sTGF-β1 and sTGF-β3 levels were positively correlated with C-reactive protein (CRP) levels in SSc patients. Additionally, sTGF-β2 and sTGF-β3 levels were positively correlated with the number of platelets in SSc patients. In skin biopsies, TGF-β1, TGF-βR1, and TGF-βR2 expression levels were higher in SSc patients than CS. In conclusion, this is the first study showing a joint decrease of the 3 active TGF-β isoforms in SSc patients. However, TGF-β1, TGF-βR1, and TGF-βR2 are possibly increased in clinically involved skin. Therefore, it is likely that a distinct role is played by TGF-β at the local (skin lesions) and systemic levels in SSc patients.
Alarmingly Low Physical Activity in Pakistani College Students Compared to American College Students
Authors: Jaffri Abbis , Jaffri Ume Abbiyha , Corbett R. O. 
Published: February 2022

Abstract
There are no studies that have investigated the physical activity (PA) trends in Pakistan, the 5 th most populated country in the world. Therefore, the aim of this study was to identify trends and differences in PA between intercollegiate students in Pakistan and the US. Three hundred (167 US; 133 Pakistani) intercollegiate students completed a cross-sectional survey used to gauge the PA levels, barriers, and literacy of intercollegiate students in both countries. American students are more likely (í µí±¥ 2 =97.27, p-value <.001) to be moderate to highly physically active in comparison to Pakistani students. American female students were more (í µí±¥ 2 =97.27, p-value <.001) active than female students in Pakistan. Independent t-test showed significantly more major barriers to PA in Pakistani intercollegiate students (6.860 ± 5.56) when compared to American intercollegiate students (3.78 ± 3.94). Out of all students 59.6%, regardless of nationality, correctly recounted the standard PA recommendations, with 1.2% of those students being Pakistani. Pakistani students were physically inactive, faced more barriers, and had lower literacy of PA. This is a novel yet extremely valuable data set for understanding the current trends in the PA status of college students in the fifth most-populated country, 60% of which is younger than 30 years of age.
A Phenotypic and Genetic Study of Semen Production and Semen Quality Traits Among Young and Adult Cattle Bulls in India
Authors: Bhave Kaustubh Gajanan , Koilpillai Thilak Pon Jawahar , Ragothaman Venkataramanan , Sontakke Shivaji , Joshi Gautami , Jadhav Rajesh , Khadse Jayant , Swaminathan Marimuthu , Ducrocq Vincent 
Published: February 2022

Abstract
Semen characteristics of 97,112 ejaculates from 399 adult bulls of 2 exotic breeds, 2 indigenous breeds and crossbred sub-populations with 50% and 75% of exotic inheritance, and of 3,293 ejaculates from 292 test bulls were analysed. The traits considered were: ejaculate volume, sperm concentration, total number of sperms, initial and post-thaw motility, and a theoretical number of doses produced from each given ejaculate. The objective was to measure the semen production potential of different genetic groups of cattle breeds, to identify factors affecting semen production and quality traits, and to assess the correlation between semen characteristics measure on test and adult bulls. A linear mixed model was used to evaluate the effect of different fixed and random effects. For adult bulls, the first ejaculate of a bull on a particular day and longer collection intervals lead to better characteristics for all the parameters but short collection interval with two ejaculate on particular day lead to a larger number of total semen doses produced without hampering semen quality. Repeatability estimates for semen traits were found to be low to moderate. Low to moderate and negative bull correlation was observed between concentration and volume in all the breed groups while the correlations of bull effects of the two motility traits were comparatively large. The moderate to high correlation for all semen traits between their testing and when they are adult highlights the importance of andrology evaluation in predicting future semen production of AI bulls in order to discard the less productive bulls.
Vocabularies And Rituals of Climate Grief In Canada: A Typology
Authors: Zurba Melanie , Boyd Sara , Lamoureux Bryanne , Mendritzki Erica , Park Andrew , Busolo David , Binkley Lisa , Woodgate Roberta 
Published: February 2022

Abstract
Climate change has become a reality for many people across Canada. Environmental changes occurring in Canadian ecoregions include: increasing temperature, more severe storms, increasing wildfire occurrence, and decreasing sea ice thickness and duration. These events are impacting mental health due to the psychological experience of grieving and loss associated with climate change. In this study, we use the term ‘climate grief’ to describe the feelings connected to both the experienced and anticipated loss due to climate change. The purpose of this study was to explore the different ways that Canadian’s express and process climate grief. A scoping review was conducted to create a typology of existing vocabularies and rituals for expressing and processing climate grief. The results of the typology found that the primary types included peer-reviewed research, media, religious/spiritual practices, education, mental health support, social action gatherings, grey literature, guiding frameworks, and artistic expression. Secondary types included 25 subtypes and 37 tertiary types/approaches. It is important for governments and medical boards to have a proactive and not a reactive position in regard to mental and physical health effects from climate change. The way that people express and process feelings associated with climate change can provide important insights for developing climate change policy and programs. Furthermore, climate change strategies should include recognition of psychological wellbeing.
CircDDX17 enhances CVB3 replication by N6-methyladenosine regulation through miR-1248/NOTCH2 targeting
Authors: Shen Hongxing , Liu Tingjun , Li Yuhan , Wang Yan , Qiao Xiaorong , yang qingru , tong jing , Deng Xintao , wang hua 
Published: February 2022

Abstract
N6-methyladenosine (m6A) is the most prevalent internal mRNA modification in eukaryotes. m6A is necessary for RNA metabolism and function, and influences RNA viruses replication. Methyltransferase-like protein 3 (METTL3) is a “writer” to regulating m6A. Coxsackievirus B3 (CVB3), belonging to the genus Enterovirus of the Picornaviridae family, are species of non-enveloped, positive single-stranded RNA virus. CVB3 infection reduces circular RNA_DDX17 (circDDX17) expression level in HeLa and HL-1 cells, as in viral myocarditis (VM). CircDDX17 enhanced CVB3 replication in HeLa and HL-1 cells and regulated NOTCH Receptor 2 (NOTCH2) by targeting microRNA-1248 (miR-1248) as microRNAs (miRNAs) sponge. NOTCH2 interaction with METTL3, through m6A proteins like methyltransferase-like protein 14 (METTL14), AlkB Homolog 5 (ALKBH5), and YTH N6-Methyladenosine RNA Binding Protein 1 (YTHDF1) to improve CVB3 replication in host cells. Taken together, this study suggests that circDDX17 targets miR-1248 to regulate NOTCH2 expression and regulates METTL3 to enhance CVB3 replication in cells by m6A relation protein.
Efficacy of Negative Pressure Wound Therapy (NPWT) Monitoring System for Postoperative Flap Management in Diabetic Foot Patients
Authors: Park Jun Ho , Park Ji-Ung 
Published: February 2022

Abstract
Background: Various types of flaps are considered as reconstructive options for patients with diabetic foot ulcer (DFU). However, flap reconstruction for DFU treatment is particularly challenging because of the relatively limited collateral perfusion in the distal lower extremity. This study evaluated the efficacy and safety of a novel postoperative monitoring procedure implemented in conjunction with NPWT immediately after flap operations for treating diabetic foot. Methods: A retrospective analysis was performed on DFU patients who underwent free flaps and perforator flaps from March 2019 through August 2021. The surgical outcomes of interest were the rates of survival and complications. On the third postoperative day, patients underwent computed tomography (CT) angiography to check for pedicle compression or fluid collection in the sub-flap plane. Monitoring time, as well as comparisons between NPWT and conventional methods, were analyzed. Statistical analysis was performed between the two groups. Results: This study included 26 patients. Among DFU patients, the NPWT group included 14 flaps and the conventional monitoring group included 12 flaps. There was no significant intergroup difference in flap survival rate (p = 0.83). In addition, there was no significant intergroup difference in the diameters of perforators or anastomosed vessels before and after NPWT (p = 0.97). Compared with conventional monitoring, the novel NPWT monitoring system was associated with a significantly lower mean monitoring time per flap up to postoperative day 5. Conclusion: Although conventional monitoring is widely recommended, especially for DFU management, the novel NPWT monitoring system investigated in this study enabled effortless serial flap monitoring and was associated with reduced infection risk compared with conventional monitoring. The novel flap monitoring technique was safe for DFU patients and is a promising candidate for future recognition as the gold standard for flap monitoring.
An Analytical Literature Review on Environmental Innovations Concepts
Authors: POPA VASILE N. , POPA LUMINITA I. , (BUTNARIU) Anca N. IUGA 
Published: February 2022

Abstract
Background: The importance of environmental innovation concepts is growing in the private sector, in academia and at the level of government policies. The concept of environmental innovation is closely related to two other notions: eco-innovation and green innovation. The purpose of this paper is to contribute to a clarification of the concept of environmental innovation and to provide an overview of the existing scientific literature in this field, identifying the most active authors, countries, publishers and relevant publications.Results: We created a matrix with a proposed eco-innovation model that is focused on the correlation between the measures related to the model application in the process of eco-innovation and the main areas of application.Conclusion: This review draws from the resource-based theory and investigates the interrelationships between three types of innovation (environmental innovation, eco-innovation, green innovation) and their impact on firm’s business performance using the proposed eco-innovation model. We found that the most active scholars are situated in US and Europe (i.e. USA, UK. Swiss, Germany, Singapore, Netherlands, Canada and France) and identified OECD as author of seven publications and Jens Horbach as author of six publications in the field of environmental innovations journals, leading the field.