bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diseño y evaluación de un curso virtual para referenciar casos de COVID-19 desde farmacias-droguerías en Colombia
Authors: Amariles Pedro , Monsalve Mauricio , Ledezma-Morales Mónica , Rivera-Cadavid Mónica , Salazar-Ospina Andrea , Ceballos Mauricio , Granados Johan , Hincapié-García Jaime 
Published: March 2022

Introducción: es necesario diseñar, implementar y evaluar la aceptación, pertinencia y usabilidad de un curso virtual orientado a favorecer la identificación y referenciación de casos sospechosos de COVID-19 desde farmacias-droguerías en Colombia.
Método: el diseño del curso se fundamentó en una ruta propuesta para la atención de usuarios sospechosos de COVID-19 que acuden a farmacias, complementada con información obtenida de una búsqueda en PubMed/Medline y en sitios Web de organizaciones referentes en el tema. La información se estructuró en un curso virtual, se elaboró y aplicó un instrumento para evaluar la cobertura, aceptabilidad y pertinencia del curso.
Resultados: se diseñó el curso virtual ¿Cómo actuamos frente al COVID-19 desde las droguerías? organizado en 7 unidades con conceptos claves para identificar y referenciar casos sospechosos de COVID-19, desde farmacias-droguerías, disponible en https://udearroba.udea.edu.co/externos/my/. Entre abril/2020 y abril/2021 se registraron 863 personas, 382 (44,3%) finalizaron el curso y se les envió el instrumento de evaluación, y fue regresado por 240 (62,8%). En este grupo, la satisfacción con el curso y material didáctico fue del 95,8% y 97,1%, respectivamente. Además, el 97,9% manifestó que el curso contribuye a identificar y referenciar casos sospechosos de COVID-19; y el 93,3% que, el acceso y navegación por el curso, resultó sencillo.
Conclusiones: se diseña, implementa y evalúa un curso virtual, abierto y usable, orientado a favorecer la identificación y referenciación de casos sospechosos de COVID-19, desde las farmacias-droguerías y, aunque los participantes declaran que contribuye con dicha finalidad, se requiere de un estudio diseñado para valorar esta aportación.
Citotoxicidad diferencial según el régimen de quimioterapia contra las células madre del cáncer de páncreas: estudio preliminar in vitro
Authors: Doello González Kevin , Francisco J.Quiñonero  , Perazzoli Gloria , Gago Lidia , Chico María Ángeles , Mesas Cristina 
Published: March 2022

Introducción: El tratamiento del cáncer de páncreas en estadios avanzados se basa en diferentes regímenes de quimioterapia. Las células madre cancerosas son responsables de la quimiorresistencia tumoral y la recurrencia tras tratamientos en etapa adyuvante y metastásica. El objetivo de este artículo fue evaluar cómo estos regímenes quimioterapéuticos afectan a la proporción de células madre cancerosas y la expresión de sus marcadores.
Método: Utilizamos la línea celular de adenocarcinoma pancreático PANC-1 como modelo para aplicar diferentes protocolos quimioterapéuticos (monoterapia y terapia combinada) utilizando 5-Fluorouracilo, Oxaliplatino, Irinotecán, Gemcitabina y Abraxane.
Resultados: Tras analizar mediante RT-qPCR diferentes marcadores de células madre tumorales (SOX2, OCT4, CD133, CD44 y CD24) en células de cáncer de páncreas tratadas con diferentes protocolos quimioterapéuticos, el Oxaliplatino y la Gemcitabina en monoterapia fueron los quimioterápicos que seleccionaron en mayor medida las células madre cancerosas mientras que el protocolo FOLFIRI las disminuyó.
Conclusiones: En cuanto a la selección de marcadores, ha sido mucho mayor en el caso de Gemcitabina en monoterapia. En conclusión, estos hallazgos podrían mejorar y personalizar la terapia del cáncer de páncreas.
Estudio comparativo de la calidad biofarmacéutica de Diazepam 10 mg comercializados en el mercado peruano
Authors: Saavedra Suárez Segundo Francisco , Curo Vallejos Yuri , Gutierrez Ramos Miriam , Alva Plasencia Pedro , Rodriguez Saavedra Lennin 
Published: March 2022

Introducción: el Diazepam pertenece a un grupo de medicamentos llamados benzodiazepinas. Se sabe que estos medicamentos actúan en el cerebro a través del GABA. Se utiliza para aliviar la ansiedad y control de la agitación causada por la abstinencia de alcohol.
Método: se evaluó la variación de peso, friabilidad, dureza, tiempo de desintegración, cuantificación de principio activo, velocidad y perfil de disolución entre el medicamento innovador y medicamentos multifuentes comercializados en el mercado peruano, según lo establecido en la USP 42.
Resultados: los resultados permitieron establecer que todas las tabletas multifuente de Diazepam 10 mg incluidos en esta investigación son bioequivalentes con la marca innovadora elegida y, por lo tanto, pueden ser intercambiables.
Conclusiones: se estableció que las tabletas multifuentes de Diazepam 10 mg incluidos en esta investigación son bioequivalentes con el innovador y, por lo que permite proponer a la comunidad científica la determinación de la equivalencia farmacéutica como elemento de apoyo en la toma de decisiones de compra en el servicio farmacéutico.
Of Self and Polity: Writing Resistance in Dixit’s Madhavi
Authors: Phuyal Komal Prasad 
Published: March 2022

Madan Mani Dixit’s novel Madhavi (1983) subtly argues for change in the existing rigid political order of his time by projecting self larger than the polity. Borrowing a narrative from the Mahabharata, the novelist develops it into a full length novel to point out the cracks in the political system of his time: as a political order, the Panchayat had lost the sense of justice within the first two decades after its promulgation in 1962. Dixit employs Galav and Madhavi as dissenting voice of the age, upholding the spirit of resistance and seeking for transformation in consciousness. The tale from the post-Vedic society serves as an instance to imply the parallel situation of the country that attempts to transcend beyond the contemporary context. In this study, I have approached the novel from the new historicist vantage point to dissect the text in the changing political context of its writing. The paper claims that as a Nepali novel, Dixit’s Madhavi rewrites the episode of political struggle between the person and polity in an oppressive political order in the 1970s in Nepal when the political self and polity were in tension as the outcome of their struggle for a new order in society. Moving beyond the existing situation, the maestro novelist picks the narrative of Madhavi and Galav from the Mahabharata and sets them in quest of new order in the form of agrarian society from the crumbling order of slavery. Dixit’s work critiques the limitations of both self and polity in leaving the impact of one on the other, thereby exposing the brutal treatment and fall of an oppressive political order. This paper reads historical reality of the 1970s in Dixit’s Madhavi in which the author writes the political history of Nepal.
Spatial Memory and Ecologically Displaced Subjectivity in Western Tharu Folk Songs of Nepal
Authors: Dangaura Mohan 
Published: March 2022

This paper critically examines the folk dance songs of Dangaura Tharu fromthe perspective of space, memory, and performance. The paper establishes the relationship between Tharu subjectivity and conscience of their past topography inherent intheir folk dance songs. In one aspect where the overall folk performance of Tharu reflects their lifestyle, in another aspect, their folk songs and rituals assist them to connect with the natural environment where they inhabit. This paper has brandied their performance as the art reflecting their bucolic lifestyle and melancholic memory. The songs have been collected, translated, and interpreted from different visual sources and personal communications. To analyze the primary texts, the notion of folklore performance from Alan Dundes, Richard Schechner, and other different folklorists have been utilized as the theoretical and review guidelines. The paper also includes the translated version of the songs. As for the indigenous culture aspirant like me, the study of folklores of Tharu indigeneity helps us to understand the spatial memory of one of the largest ethnicity of Nepal and their socio-economic history. It will provide a new perspective of their historical changes from literature which have not been critically assessed in the already conducted studies. Hence, the findings of the research help us to understand the necessary social index of one of Nepal’s largest indigeneity.
Cultural Practice of Natural Theology and Environmental Ethics in the Vedas
Authors: Chalise Keshav Raj 
Published: March 2022

Vedic texts have established the cult of worshipping natural phenomena, which from the surface understanding is the process of personification, but in real, Vedic hymns show on how the Vedic people have understood the underlying power of nature. Vedas, Rig Veda, Sama Veda, Yajur Veda and Atharva Veda, have joined the human culture with the philosophy of nature in the mode of natural theology. The culture of sacrifice taught through Vedic hymns has conveyed the knowledge of mutual dependence of man, God and nature. Vedas have proven the natural theological notion of nature-God relation with the hymns devoted to nature phenomena as the metaphors of power, creativity, essence and purity in the forms of deities. Vedas have pertained ecocentrism as the cultural practice of nature eminence. They have further addressed the idea of environmental ethics through the Vedic view of cosmological and ontological unity in nature, and the ethics of natural law in the form of rita, dharma and karma. With the examination of Vedic priority to nature, especially from the Rig Veda, this study anticipates to link Vedic natural religion with the nineteenth century philosophy of natural theology and late twentieth century ecological study of environmental ethics.
VIRTUAL CFRP STRENGTHENING OF NON-PRISMATIC RC BEAMS WITHOUT LATERAL REINFORCEMENT
Authors: Hameed Aziz Ali 
Published: March 2022

The provision of the international codes does not cover clearly the design of non-prismatic reinforced concrete beams and the design has been left to the experience and judgment of design engineers. In the present paper, four beam specimens were cast and tested, one of which was poured as a prismatic beam (reference beam), while, the others were poured with non-prismatic sections. Virtual strengthening with bonded CFRP strips was adopted as an alternative technique instead of the real lateral reinforcement (stirrups) to evaluate the degree at which the load-carrying capacity of tested beam specimens was enhanced. Finite element method, as a numerical solution by ANSYS software, was adopted to simulate all the tested beam specimens which presented as three-dimensional problems. Experimental results show that the degradation due to tapering was varied between (50-94%) and (53-81%) for the ultimate and cracking load respectively, in comparison with the reference beam. While the analysis results indicated that the adopted technique plays important parameters to enhance the performance of the strengthened beams and the presence of CFRP increased the strength in the case of stirrups-less beams.
EFFECT OF ULTRAVIOLET ON OUTDOOR WORKERS
Authors: B. Mohsin Bushra , A. Khaleefa Ali Seroor 
Published: March 2022

The sunlight mainly affected the development of this life on the surface of the globe, most people love and enjoy the sunlight and its warmth, but fear its harmful effects from sunburn and long-term damage to the skin due to excessive exposure to the sun, and thus people began to seek for protection from the sun's rays. To avoid the pain of sunburn and its harmful effects, and since the internal workers are protected from the sun's rays, outdoor workers are more exposed to ultraviolet rays and are more exposed to adverse consequences from the effects on the eyes and skin, although most of the body is protected by clothing, it is not sufficient, the size of the risks depends. On the skin and the increase in skin cancer incidence based on several factors, climatic factors or according to the sensitivity of the personality to ultraviolet rays, this is wholly related to personal habits related to sunlight. This research paper measured ultraviolet rays on Baghdad's outdoor workers, although temperature and UV index. At the beginning of November 2020, the results showed that exposure to ultraviolet rays is significantly related to temperature, UV index, and cloud cover, where P-vale is less than 0.001. Farther more, there is increased exposure to UVB as well as UVA.
Anti-fungal Activity of Punica Granatum I.peels Powder and Extracts from Pathogenic Samples
Authors: S.Shaokat Siham , A.Hameed Hamoudi , J.Mohammad Hassan 
Published: March 2022

Thirty five samples were collected from patients (1-30) years old, suffered from, infected skin , rushes, boils , oral thrush, anal & vaginal itches. Candida albicans 57.3% (20 isolates) and Candida tropicalis 22.5% (8 isolates) Aspergillus fumegatus 11.5% (4 isolates) Aspergillus nigar 8.7%(3 isolates) , were isolated & identified from these samples. Alcoholic & water hot extracts of the punica granatum (Pomegranate) peels as well as the dried powder were prepared. The anti-fungal activity of the extracts was evaluated by means of the agar-well diffusion assay. The extract exhibited potent activity against yeast. The Minimum inhibitory concentrations were 128-1024 Î¼g/ml against Candida albicans and Candida tropicalis .Their was little difference between the activities of alcoholic extract & aqueous extract. These results suggest the Pomegranate Peels extract which contains gallotanic acid as a promising anti-fungal agent.
Key wards : Antifungal agents, Plant extracts, Candida isolation
The Release of Diazepam from Different Conventional and Hollow Type Suppository Bases
Authors: A. Kamal Balkis 
Published: March 2022

The objective of this study was to investigate the release profile of different fat and water soluble bases using diazepam as a model drug , and then to develop a satisfactory formula with a rapid release of diazepam from suppository bases .The study was conducted using theobroma oil ,glycerol-gelatin and glycerol-PEG1540 bases using conventional mold method for preparation .while the later base was utilized to incorporate diazepam ( buffered solution ) in a hollow type suppositories. The results indicated that all types of bases can be utilized to formulate diazepam as rectal suppositories with acceptable disintegration time ( 12, 10, 6, and 6min.), respectively . While 100% of the released drug had been shown different release profiles with different storage time ( 15, 30, and 45 days ) in a refrigerator at 5Â°C , best results were obtained , when glycerol- PEG1540 used as a base for both conventional and hollow type mold methods .However , a decrease in the release rate of the drug was seen with glycerol-gelatin and glycerol-PEG1540 and to a lesser extent for glycerol-PEG1540 prepared
by hollow type method .
Key words: Diazepam , Hollow type suppository
Characterization of the biochemical and nutritional content in simple white grain maize (Zea mays L.) crosses
Authors: Sánchez-Ramírez Francisco J. , Mendoza-Castillo M.C. , Mendoza-Mendoza C.G. , Delgado-Alvarado A. 
Published: March 2022

E
Objective: To characterize the nutritional and biochemical content of 25 genotypes: 5 S4 inbred lines and the 20 possible single crosses formed between them.
Design/Methodology/Approach: The content of oil, starch, protein, ash and phytic acid was determined in kernels of each genotype, using the American Association of Cereal Chemists’ methods; the information obtained was analyzed by a complete randomized experimental design and Tukey’s means tests.
Results: For the parents and the crosses, correspondingly, the intervals of the substances under study were: a) Oil: from 5.99 to 3.84 and 6.40 to 3.55 g ∙ 100 g-1, b) Protein: from 8.26 to 5.43 and 9.83 to 5.56 g ∙ 100 g-1, c) Starch: from 88.25 to 74.48 and 96.64 to 72.57 g ∙ 100 g-1, d) Ash: from 1.90 to 1.20 and 2.0 to 0.89 g ∙ 100 g-1, e) Phytic acid: from 2.40 to 1.08 and 2.29 to 1.11 g ∙ 100 g-1.
Study Limitations/Implications: The study shows that in comparison to the parents, the crosses were only significantly superior in the content of starch, although there were statistical differences of the contents within each group. The crosses that showed higher contents for a nutritional component were those in which at least one parent had a high composition of the nutrient.
Findings/Conclusions: The variation in the nutritional and biochemical content showed that there is diversity among genotypes, which is linked to the contrasting genetic origin of the inbred lines and is feasible to be used. This research showed the potential of taking advantage of the nutritional components of white maize through crosses (specially its starch content).
Young Invesment 2021: Webinar Dan Training Untuk Generation Z
Authors: Genoveva Genoveva , Sukarno Fujianti Nur L. , Fajrin M. Akbar , Dong Zi Yuan 
Published: March 2022

ABSTRAK Perkembangan teknologi digital dan kondisi pandemi COVID-19 yang melanda Indonesia membawa berbagai dampak, salah satunya adalah peluang bagi generasi Z dalam mempelajari investasi. Berdasarkan hasil penelitian generasi Z adalah jumlah terbesar yang melakukan investasi yaitu 46,75%. Kemudahan mengakses lembaga keuangan secara digital, termasuk belajar secara mandiri melalui platform digital serta pengaruh sosial media meningkatkan jumlah investor yang berasal dari generasi Z yang sudah akrab dengan teknologi. Hasil penelitian ini didukung oleh hasil survei pelaksana PKM ke SMA dan perguruan tinggi, dimana para siswa dan mahasiswa sudah melakukan investasi dengan uang saku mereka. Namun, generasi Z sebagai generasi yang masih kurang pengalaman serta secara emosional masih labil memerlukan pendampingan dan pemahaman yang baik mengenai cara berinvestasi. Tim pelaksana PKM mengadakan webinar dan pelatihan untuk memberikan pengetahuan dalam berinvestasi dan memberikan rasa percaya diri ketika mengambil keputusan dalam berinvestasi. Hasil pelaksanaan PKM menyimpulkan bahwa para peserta mempeoleh manfaat berupa bertambahnya pengetahuan dan meningkatnya kepercayaan diri serta kemandirian dalam berinvestasi, disamping itu terdapat manfaat sosial yaitu mendapat teman baru dan relasi. Kata kunci: investasi; generasi Z; Pengabdian kepada masyarakat ABSTRACTThe development of digital technology and the COVID-19 pandemic has brought various impacts to Indonesian citizens, one of which was an opportunity for generation Z to study investment. Research has shown that generation Z makes up the majority of investors today, which is 46.75%. The ease of accessing financial institutions digitally, including learning independently through digital platforms, as well as the influence of social media has increased the number of investors from generation Z who are already familiar with technology. The results of this study are supported by the results of a social community team survey on high schools and colleges, where students have invested with their pocket money. However, generation Z, as a less experienced and emotionally unstable generation, requires assistance and a good understanding of how to invest. Our social community team has been holding webinars and providing training for young investors. The participants have greatly benefited from our social community as well as increased self-confidence and independence in making investment decisions. Keywords: investment; generation Z; social community
Sistem Informasi Manajemen Berbasis Android Di SMK Kabupaten Peringsewu
Authors: Rini Riswanti , Hariri Hasan , Nurbanati Eis , Hermanto Deddy , Efendi Ujang 
Published: March 2022

ABSTRAKSistem Informasi Manajemen adalah seperangkat prosedur gabungan yang mengumpulkan dan menghasilkan data yang andal, relevan, dan terorganisir dengan baik yang mendukung proses pengambilan keputusan suatu organisasi. Tujuan Sistem informasi manajemen (SIM) digunakan oleh sekolah untuk mendukung serangkaian kegiatan administarasi termasuk pemantauan kehadiran, catatan penilaian, pelaporan, manajemen keuangan, dan alokasi sumber daya dan staf. SIM memberikan informasi yang dibutuhkan manajer untuk mengelola organisasi secara efisien dan eefektif. Metode dalam penelitian ini adalah metode praktek pelatihan dan diskusi sosialisasi. Hasilnya meningkatkan pemahaman tentang SIM Berbasis Android dengan meniingkatan layanan pendidikan yang efektif dan efesian. Saran kedepannya dengan pelatihan SIM Android yang sudah diaplikasikan dapat digunakan di skeolah lainnya. Kata Kunci: SIM, Android, Manajemen ABSTRACTManagement Information System is a set of combined procedures that collects and produces reliable, relevant and well-organized data that supports the decision-making process of an organization. Objectives The management information system (MIS) is used by schools to support a range of administrative activities including attendance monitoring, assessment records, reporting, financial management, and resource and staff allocation. MIS provides the information managers need to manage an organization efficiently and effectively. The method in this research is the method of training practice and socialization discussion. The results increase understanding of Android-Based MIS by increasing effective and efficient educational services. Suggestions in the future with Android SIM training that has been applied can be used in other schools.Key Words: MIS, Android, Management
Edukasi Vaksin Covid 19 Dan Penerapan Protokol Kesehatan Dengan 5M Serta Membagikan Masker, Handsanitizer Di RSUD Arifin Achmad Pekanbaru
Authors: Ekaputri Mersi , Jannaim Jannaim , Rahmaniza Rahmaniza , Ramadia Arya 
Published: March 2022

ABSTRAKIndonesia masih menjadi penyumbang angka penderita Covid 19 yang masih terus meningkat di dunia padahal pemerintah dan seluruh elemen masyarakat telah berupaya mensosialisasikan penerapan protokol kesehatan. Dalam upaya pemutusan penyebaran Covid 19 dinilai masih lemah dan masyarakat pun masih belum sepenuhnya patuh menerapkan protokol kesehatan. Sebagai upaya menanggulangi permasalahan tersebut perlu sosialisasi dan edukasi seputar vaksin Covid 19 dan penerapan protokol kesehatan dengan 5M. Tujuan dari kegiatan ini memberikan informasi dan meningkatkan kesadaran pasien dan keluarga yang berkunjungnke rumah sakit tentang pentingnya vaksin covid 19 dan penerapan protokol kesehatan dengan 5M. Sasaran kegiatan ini adalah pasien dan keluarga pasien yang datang ke RSUD Arifin Achmad Pekanbaru. Metode yang digunakan adalah dengan melakukan presentasi materi, membagikan masker dan handsanitizer. Hasil dari kegiatan ini adalah pasien dan keluarga lebih dari separoh (75%) memahami tentang pentingnya vaksin dan penerapan protokol kesehatan dengan 5M dalam kehiduap sehari hari terutama pada kondisi pandemi covid 19. Kata Kunci : Edukasi, Covid 19, Protokol Kesehatan. ABSTRACT Indonesia is still a contributor to the number of COVID-19 sufferers, which is still increasing in the world, even though the government and all elements of society have tried to socialize the implementation of health protocols. In an effort to stop the spread of Covid-19, it is still considered weak and the community is still not fully compliant with implementing health protocols. As an effort to overcome these problems, it is necessary to socialize and educate about the Covid 19 vaccine and the application of the 5M health protocol. The purpose of this activity is to provide information and increase awareness of patients and families visiting hospitals about the importance of the COVID-19 vaccine and the implementation of health protocols with 5M. The target of this activity is patients and their families who come to Arifin Achmad Hospital Pekanbaru. The method used is by presenting the material, distributing masks and hand sanitizer. The result of this activity is that more than half (75%) of patients and families understand the importance of vaccines and the application of health protocols with 5M in their daily lives, especially during the COVID-19 pandemic. Keywords: Education, Covid 19, Health Protocol.