bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prediction of Urinary Tract Infection in Neonates with Unexplained Indirect Hyperbilirubinemia
Authors: Abdelrheem Shaimaa S. , Aly Hanan Mohammed , Diab Fatma , Maebed Ashraf , Osman Asmaa O. B. , Mhsb Ahmed H. , Alaswad Nadia K. , Darwish Taher M. , Gabri Magda Farghali 
Published: August 2022

Background: Neonates with urinary tract infection (UTI) are susceptible to higher rates of morbidity and mortality, specifically when presented with hyperbilirubinemia. Screening for UTIs in jaundiced neonates is a cost-effective strategy. The aims of this study were to investigate the pattern of UTI (prevalence, etiology, and susceptible antimicrobial agents) in neonates admitted to the NICU with unexplained indirect hyperbilirubinemia, as well as to identify early predictors of UTI in order to reduce the present morbidity and long-term consequences in NICU patients.
. Methods: A cross-sectional hospital-based study that included 140 neonates diagnosed with unexplained indirect hyperbilirubinemia in the first 4 weeks of life. A questionnaire was applied to obtain demographic and clinical data. A number of laboratory parameters were assessed with clinical examination. Bacterial growth of 1 × 103 colony-forming units/mL of a single uropathogen was used to identify the existence of UTI. Multivariate analysis was used to identify the predicting factors of UTIs. Results: In the NICU group investigated, 25.7% of subjects had a culture-proved UTI. The most frequently isolated organism was Escherichia coli. Amikacin was the most common antibiotic that the isolates were susceptible to. In multivariable logistic regression analysis, a positive urine culture was statistically associated with an increase in WBCs (OR= 6.90, p= 0.001), pyuria (OR= 5.55, p= 0.001), small for gestational age (OR= 4.07, p= 0.021), prolonged phototherapy duration (OR= 3.50, p= 0.034), and the presence of obstetric complications (OR= 2.92, p= 0.001). Conclusion: UTI is substantially prevalent among neonates admitted to the NICU with unexplained indirect hyperbilirubinemia. The importance of routine UTI screening (urine culture) as part of the clinical assessment of unexplained hyperbilirubinemia was highlighted in this study, particularly in neonates with leukocytosis, pyuria, small for gestational age, prolonged phototherapy, and those born from mothers with a history of obstetric complications.
Sérialiser la Série Noire
Authors: Frenay Adrien , Quaquarelli Lucia 
Published: August 2022

L’étude du fonds Gallimard/Duhamel conservé à la Bibliothèque des Littératures Policières permet de comprendre le processus de production des romans parus dans la collection « Série Noire ». D’une part, l’analyse des marques présentes sur les exemplaires américains ayant servi à la traduction de 1945 à 1955 et d’une partie de la correspondance de Marcel Duhamel montre que les modifications apportées par l’équipe de la Série Noire aux romans anglo-américains traduits sont significatives et systématiques ; qu’elles réorientent, parfois profondément, la narration ; enfin qu’elles servent avant tout à créer un effet sériel. D’autre part, les interventions, qui prennent principalement la forme de coupes, remettent à l’état d’épreuve ou de brouillon des romans pourtant déjà publiés aux États-Unis ou au Royaume-Uni. Elles mettent donc en question certaines notions de la théorie de traduction comme celle d’« original », de texte « source » et de « fidélité » et, plus généralement, celle d’auctorialité – qui devient en l’occurrence collective et s’élargit à plusieurs acteurs de la fabrique éditoriale.
Génétique du best-seller
Authors: Amir Lucie 
Published: August 2022

Marchandise culturelle par excellence, le best-seller, et a fortiori le best-seller de genre, qui s’écrit « à la chaîne », a peu intéressé la génétique des textes jusqu’ici. On l’analyse généralement au prisme de sa fabrique médiatique et commerciale, et lorsqu’on s’arrête sur sa création à proprement parler, c’est souvent pour prétendre qu’il existe à l’origine du best-seller une pratique mécaniste de l’écriture, qui reposerait sur la reproduction de « recettes » qui « marchent ». À travers l’exemple de Michel Bussi, l’un des romanciers français qui vend le plus actuellement, cet article confronte les soupçons qui pèsent sur les écrivains à succès à la fabrique littéraire effective de deux de ses romans. Il met au jour la manière dont le best-seller, comme réalité économique et comme expérience auctoriale, peut influencer aujourd’hui la création littéraire.
Creuser les sous-sols de la pensée
Authors: Paone Domenico 
Published: August 2022

Questionnant les motivations qui ont poussé les écrivains à léguer leurs manuscrits à la postérité, l’article se concentre sur le cas d’Ernest Renan, l’un des premiers à avoir exprimé ce vœu. L’analyse de son testament olographe révèle une pulsion narcissique, qui reflète l’importance qu’il avait de son rôle dans le milieu intellectuel de la fin du xixe siècle, mais aussi et surtout une précise conscience philologique de ce qu’un manuscrit peut représenter pour les chercheurs à venir. En suivant le cheminement de l’écriture de Renan à travers une série de notes préparatoires, l’article montre ensuite la dynamique de « fixation » des idées, oscillant entre une écriture de l’intime, du rêve, et le travail minutieux sur les sources textuelles, entre endogenèse et exogenèse. Fouillant le passé des textes pour faire émerger les traces du processus de création, la démarche génétique rencontre ainsi les vœux de l’auteur, qui incitait ses futurs critiques à se faire « archéologues » de sa pensée.
Maternal and child health service readiness among primary health care facilities in Ekiti, Nigeria
Authors: Oluwole Esther O. , Adeniran Adeyinka , Chieme Chisom F. , Ojo Omobola Y. , Akinyinka Modupe R. , Ilesanmi Marcus M. , Olujobi Babatunde A. , Bakare Omowunmi Q. 
Published: August 2022

Background: The availability of adequate infrastructure, diagnostic medical equipment, medicines and commodities and well-trained medical personnel are essential for the effective delivery of health care services.Aim: This study assessed maternal and child health (MCH) services’ specific readiness by type and location of the health facility and compared the readiness between urban and rural primary health care (PHC) facilities in Ekiti State, Nigeria.Setting: The study was conducted amongst the heads (officers in charge) of PHC facilities in Ekiti State, Nigeria between August 2020 and October 2020.Methods: A descriptive cross-sectional study in which all PHC facilities were conducted and data were collected with the aid of the Service Availability and Readiness Assessment (SARA) tool using the KoboCollect app. Data were cleaned and coded on Microsoft Excel 2016 and exported to Stata SE 12 for analysis. The level of significance was set at p 0.05.Results: Overall, the MCH readiness score amongst PHC facilities was 47% (0.47 ± 0.18). About half (52%) of the facilities had necessary and relevant equipment. Health facilities located in urban areas had more medicines and commodities compared with those of rural areas (0.51 ± 0.16 vs 0.45 ± 0.17, p 0.05). Primary health care facilities in Ekiti North I had an overall higher service readiness score (0.63 ± 0.19) compared with other federal constituencies (p 0.001).Conclusion: The overall MCH-specific service readiness in Ekiti State was relatively low. Strategies to address the identified gaps for a smooth journey towards the achievement of Universal Health Coverage (UHC) are recommended.
Mixed Reality in the Reconstruction of Orbital Floor: An Experimental and Clinical Evaluative Study
Authors: Rahimov Chingiz R. , Aliyev Daniz U. , Rahimov Nurmammad R. , Farzaliyev Ismayil M. 
Published: August 2022

Introduction
Orbital floor fractures are common within midface fractures. Their management includes restoration of orbital volume and anatomy. However, these procedures could be associated with the mispositioning of implants and inadequate volume restoration. Nowadays medical rapid prototyping, virtual planning (VP), and navigation systems significantly increase the precision of such procedures. Nevertheless, the application of intraoperative navigation could be associated with intraoperative mistakes related to two-dimensional imaging. The application of mixed reality (MR) could solve this problem. The current study aims to demonstrate the application of MR in orbital reconstruction.

Materials and Methods
The current study included experimental and clinical implementation of MR in orbital reconstruction. Within the experimental part, 10 residents and 5 experienced maxillofacial surgeons were added. All data and customised software were well documented and then used in a single clinical case of orbital floor reconstruction.

Results
Visual assessment of plate positioning within the experiment revealed proper plate positioning in 8 cases. A comparison of virtual and real measurements showed a stable deviation of 0.65–1.15 (mean 0.9 mm). As a result of the clinical implementation of MR technology, after surgical reconstruction, the patient showed improvement in ocular mobility and reduction of diplopia. A postoperative computed tomography scan showed proper plate positioning.

Discussion
Implementation of MR based on VP could significantly improve the results of preoperative planning, intraoperative navigation, and surgery. However, existing technical limitations that relate to navigation principles could produce mistakes and errors. Therefore, further investigations related to the 6 degrees of freedom problem solution are considered reasonable in the elimination of listed issues.
Comparison of Functional and Survival Outcomes in Pedicled and Microsurgical Flap Reconstruction for Near-Total and Total Glossectomies
Authors: Saldanha Elroy , Patel Dhruv G. , Desai Sanjay M. , Dhakad Vinod , Joseph Bonny , Ghosh Sandeep , Monteiro Ashma 
Published: August 2022

Introduction
Patients with advanced carcinoma tongue end up with near-total/total glossectomy (NTG/TG). We intended to compare functional, oncological, and survival outcomes of patients undergoing pedicled and microsurgical flap reconstruction in NTG/TG patients at our hospital.

Methodology
A prospective study was conducted for 7 years on 91 patients with carcinoma tongue who underwent NTG/TG at our institute. Patients underwent anterolateral thigh (ALT), free radial artery forearm flap (FRAFF), and pectoralis major myocutaneous (PMMC) flap reconstruction and were followed up for immediate complications and functional outcomes for speech, swallowing, and decannulation after completion of adjuvant treatment and then for survival rates for a period of 60 months and statistically analysed with log rank test and Fisher’s exact test for correlation.

Results
Ninety-one (42.85%) patients underwent NTG, while 57.14% underwent TG. 85% of patients had >5 mm margin, 14% had ≤ of 5 mm, and none were positive. 57% of patients did not have postoperative complications and 10% underwent re-exploration. During follow-up, 85.7% of patients were able to take orally: 52% soft diet and 32% liquid diet. Multivariate analysis of individual flaps, swallowing, and speech intelligibility values were significant. After 5 years of postadjuvant therapy, there was 76% overall survival, 11% local recurrence and 12% had regional recurrence.

Discussion
Morbidity and functional outcome depends on the extent of resection. PMMC flaps can be done on lack of expertise. FRAFF has better functional outcomes owing to pliability of flap. ALT and other bulky flaps require expertise and are prone to flap-related complications. Planning of reconstruction should be based on the defect size together with counseling of patients regarding the risk of complications and delay in adjuvant therapy.
Management of Mandibular Nonunion Fracture with Single-Piece Implant - A Case Report
Authors: Gaur Vivek , Doshi Anita Gala , Bengani Aroon K. S. 
Published: August 2022

Rationale
This paper presents the treatment of noninfected hypertrophic, horse hoof nonunion edentulous mandible accompanied with a Luhr class fracture.

Patient Concerns
The patient reported with complaints of pain and an unstable lower denture at the right side of the lower jaw post mandibular fracture.

Diagnosis
Upon inspection and post cone-beam computed tomography, it was determined that it was a case of a noninfected hypertrophic, horse hoof nonunion edentulous mandible with Luhr class 1 fracture.

Treatment
The clinicians in this study treated the fracture with single-piece corticobasal jaw implants successfully with 10 BECES® corticobasal single-piece jaw implants in the maxilla by engaging double pterygoids bilaterally and eight implants in the mandible.

Outcomes
After two years, complete unification of the fracture line and callus adaptation was observed on a panoramic radiograph.

Take-away Lessons
The authors propose a new treatment option for the correction of nonunion mandibular fracture.
Rigid versus Resorbable Plate Fixation in Fronto-Orbital Advancement in Unicoronal Stenosis - A Retrospective Study
Authors: Balaji S. M. , Balaji Preetha 
Published: August 2022

Introduction
Rigid plating fixation (RPF) and resorbable plating systems (RPS) advanced the field of reconstruction in craniomaxillofacial region. However, their performance in patients, particularly the effect on bone remodeling at site of hardware placement is not much documented. This manuscript aims to compare the performance of RPF and RPS in a cohort using a retrospective audit of case records.

Methods
Archival records were searched for patients who had undergone cranial metal-RPF or RPS or combination for the correction of craniofacial deformities following inclusion-exclusion criteria. From records, data of the quality and quantity of bone formed along the site of plate fixation as compared with the adjacent site, accommodating or facilitating brain growth, and persistence of bone deformity at the site of hardware placement were collected at the end of the follow-up period. A total of 128 sites from 18 individuals (6 with exclusive metal-RPF and 12 with RPS) mean age of 7.45 ± 7.28 (Median 4; IQR of 8.88;2.6–11.5) who underwent cranial bone remodeling surgery formed the study group.

Results
There was a statistically significant difference between the RPF and PRS system at the fronto-orbital suture (P = 0.002) and coronal suture (P = 0.036) with bone quality and quantity.

Discussion
The RPF system was rigid but had a set of issues, while RPS has advantages and limitations. The qualitative difference in between the two systems is different. Due to inherent dissimilarity, the two systems cannot be interchanged and due diligence has to be exercised while deciding on the system. More prospective studies are needed to validate the findings.
Melanotic Neuroectodermal Tumour of Infancy - A Case Report and Review of Literature
Authors: Jakka Sabareesh , Roy Indranil Deb Brig. , Rangan Mohan , Pandey Satyanarayan , Singh Anup Kumar 
Published: August 2022

Rationale
Melanotic neuroectodermal tumour of infancy (MNTI) is universally described as a rare, benign, pigmented lesion which most frequently involves the maxilla. Its origin is well established to be in the neural crest cells. Due to the high recurrence rate and aggressive behaviour mimicking malignancy, it poses a great challenge in their diagnosis, treatment planning, and prognosis.

Patient Concern
Two-year-old female with no known comorbidities was brought in with the chief complaint of a growing swelling in the upper lip region.

Diagnosis and Treatment
She was taken up for resection of the tumour under general anaesthesia. The specimen was subjected to histological and immunological examination confirming the diagnosis of MNTI.

Outcome
The postoperative period was uneventful. After regular follow-up, the patient showed satisfactory healing with no signs of recurrence.

Take-Away Lessons
Based on our experience, we feel that the diagnosis of MNTI is mainly clinical. Early conservative surgical excision and regular follow-up provide an excellent result with good prognosis.
IDENTIFIKASI STRUKTUR BAWAH PERMUKAAN BERDASARKAN DATA ANOMALI MEDAN GRAVITASI GGMPLUS DI KABUPATEN KONAWE SELATAN, SULAWESI TENGGARA
Authors: Utami subhan Ainun Ayu , Hamimu La , Rubaiyn Al 
Published: August 2022

Data gravitasi citra satelit GGMplus merupakan data yang menyediakan peta medan gravitasi terkomputerisasi dengan resolusi antar titik yaitu 220 m sehingga baik dalam penentuan struktur bawah permukaan. Telah dilakukan penelitian pengukuran medan gravitasi untuk mengetahui pola persebaran anomaly Bouguer dan mengidentifikasi struktur geologi di daerah Kabupaten Konawe Selatan khususnya pada daerah Pamandati. Pengukuran data medan gravitasi menggunakan data gravitasi citra satelit GGMPlus (Global Gravity Model Plus). Pengolahan data dilakukan menggunakan Software Oasis Mountaj. Koreksi yang dilakukan berupa koreksi Bouguer, koreksi terrain, proyeksi pada bidang datar, analisis spektrum, pemisahan anomali regional dan residual menggunakan metode Moving Average dan pemodelan struktur bawah permukaan. Hasil anomali Bouguer lengkap dan anomali lokal menunjukkan pola persebaran anomali dari Barat Laut-Tenggara, yang relatif sama dengan dengan arah struktur di daerah penelitian. Berdasarkan hasil pemodelan peta anomali residual mengindikasikan adanya intrusi batuan beku di bagian Tenggara daerah penelitian. Intrusi pertama terletak pada kedalaman ±800 meter, dan intrusi kedua terletak pada kedalaman ±1200.
Urgensi Minat Menghafal Al-Qur’an dan Kemampuan Berbahasa Arab Bagi Peningkatan Prestasi Tahfizh Al-Qur’an
Authors: Nasier Gamal Abdel 
Published: August 2022

Secara umum tujuan pengajaran bahasa Arab di Indonesia tidak terlepas dari fungsinya sebagai sarana untuk mengkaji dan mendalami ilmu agama Islam, kebudayaan, ilmu pengetahuan, dan sebagai sarana komunikasi antar bangsa. Oleh karena itu pelaksanaan pengajaran bahasa Arab di Indonesia haruslah memperhatikan keseimbangan antara pengusaan secara lisan dan tulisan.
Mempelajari bahasa Arab bagi masyarakat non Arab, tetap saja memiliki banyak kendala dan problematika yang dihadapi karena bahasa Arab bukanlah bahasa yang mudah untuk dikuasai secara total. Namun mempelajarinya menjadi sesuatu yang tak bisa diabaikan begitu saja. Kebutuhan akan bahasa Arab bagi masyarakat dunia saat ini cukup tinggi, baik bagi muslim maupun non muslim.
Sebagaimana telah dijelaskan di atas kandungan bahasa Al-Qur’an yang berasal dari bahasa Arab memberikan keunikan tersendiri bagi setiap orang untuk menghafal Al-Qur’an, mengingat bahasa setiap negara berbeda hal ini merupakan tantangan bagi setiap individu yang akan memantapkan diri untuk menghafal Al-Qur’an.
Adanya kekhususan bahasa Al-Qur’an ini telah memberikan semangat dan kemauan masyarakat dalam belajar bahasa Arab. Upaya yang dilakukan tersebut adalah untuk mempermudah dalam menghafal Al-Qur’an. Selain itu dengan memahami bahasa Arab memungkinkan seseorang seseorang dapat dengan mudah mengerti dan memahami isi kandungan Al-Qur’an. Minat menghafal Al-Qur’an dan kemampuan berbahasa Arab kiranya dapat menjadi pengaruh seseorang dalam berprestasi terhadap hafalan Al-Qur’an
Claudin-18
Authors: Wong Mary T. , Singhi Aatur D. , Larson Brent K. , Huynh Carissa A. T. , Balzer Bonnie L. , Burch Miguel , Dhall Deepti , Gangi Alexandra , Gong Jun , Guindi Maha , Hendifar Andrew E. , Kim Stacey A. , de Peralta-Venturina Mariza , Waters Kevin M. 
Published: August 2022

Context.—
Claudin-18 is expressed in some gastric cancers. Clinical trials are evaluating it as a therapeutic target.

Objectives.—
To evaluate claudin-18 expression in intestinal metaplasia, dysplasia, and adenocarcinoma of the distal esophagus/gastroesophageal junction and stomach and to evaluate claudin-18 expression in gastric and nongastric neuroendocrine tumors as a marker of gastric origin.

Design.—
Samples included gastroesophageal junction with intestinal metaplasia (n = 40), dysplasia (n = 54), and adenocarcinoma (n = 20) and stomach with intestinal metaplasia (n = 79), dysplasia (n = 43), and adenocarcinoma (n = 25). Additionally, gastric (n = 40) and nongastric (n = 322) neuroendocrine tumors were included. Claudin-18 expression was evaluated for any staining as positive and by meeting clinical trial inclusion criteria (≥2+ intensity in ≥50% of tumor).

Results.—
Claudin-18 staining was not significantly different across dysplasia categories in the gastroesophageal junction (P = .11) or stomach (P = .12). The rate of positive staining was higher in gastroesophageal junction than stomach for intestinal metaplasia (37 of 40 [92.5%] versus 37 of 79 [46.8%]; P &lt; .001) and high-grade dysplasia (33 of 38 [86.8%] versus 9 of 16 [56.3%]; P = .03). Intestinal metaplasia showed staining in 7 of 37 autoimmune gastritis samples (18.9%) compared with 30 of 42 samples without autoimmune gastritis (71.4%) (P &lt; .001). Adenocarcinoma showed similar staining in gastroesophageal junction (15 of 20; 75.0%) and stomach (17 of 25; 68.0%) (P = .85). Eighty percent (32 of 40) of gastric neuroendocrine tumors were positive for claudin-18 expression, with 57.5% (23 of 40) meeting clinical trial inclusion criteria. Comparatively, 0.62% (2 of 322) of nongastric neuroendocrine tumors showed staining (P &lt; .001).

Conclusions.—
Claudin-18 staining was similar in intestinal metaplasia, dysplasia, and adenocarcinoma. Claudin-18 was negative in most cases of intestinal metaplasia in autoimmune gastritis, indicating that intestinal metaplasia in this setting may differ from other forms. Claudin-18 was sensitive and specific for gastric origin in neuroendocrine tumors.
Nephrogenic Adenoma Intermixed With Urothelial Carcinoma
Authors: Kryvenko Oleksandr N. , Wasco Matthew J. , Williamson Sean R. 
Published: August 2022

Context.—
Nephrogenic adenoma (NA) is a common urinary tract lesion typically associated with urothelial disruption, leading to implantation of shed renal tubular cells. NA may demonstrate a spectrum of architectural and cytologic features mimicking urothelial carcinoma (UC), adenocarcinoma (including clear cell adenocarcinoma and prostatic adenocarcinoma), and invasion. However, admixed UC and NA has not been described.

Objective.—
To describe cases where the NA was intimately intermixed with UC, potentially mimicking variant differentiation or invasion.

Design.—
In 3 health care systems we identified specimens of NA and UC intimately intermixed with each other to the extent that they could mimic a spectrum of one lesion. We assessed patterns of NA and clinical implications of misdiagnosing NA as glandular differentiation of UC.

Results.—
There were 4 women and 29 men (median age, 72 years; range, 31–89 years). Twenty-four patients had transurethral resections, 3 had biopsies, and 6 had major resections. Fourteen had noninvasive high-grade papillary UC, 6 had carcinoma in situ, and 11 had invasive high-grade UC. In 2 patients, NA developed in a papillary urothelial neoplasm with extensive denudation. Three patients had fibromyxoid NA infiltrated by invasive UC. Classical NA (n = 30) had tubulopapillary (n = 18), pure tubular (n = 7), or pure papillary architecture (n = 5). In 1 lesion, NA was present in muscularis propria, and 2 lesions involved adventitia. NA could have been misdiagnosed as invasion in 17 of 22 (77%) noninvasive tumors or higher stage in 19 of 33 (58%).

Conclusions.—
NA can be intermingled with high-grade UC, expanding the spectrum of entities that must be considered in the differential diagnosis, as it may mimic glandular or tubular differentiation, invasion, and a higher stage of disease. Misinterpretation of NA in such a setting may incorrectly convey a more aggressive biological potential of cancer to clinicians.