bluuebunny/crossref_metadata_2025_split huggingface dataset:
179 Safety and Feasibility of Platelet-Rich Plasma Injections for Peyronie's Disease: Update From a Single-center Double-blind Placebo-controlled Randomized Trial
Authors: Chu K. , Masterson T. , Efimenko I. , Molina M. , Saltzman R. , Ibrahim E. , Ramasamy R. 
Published: April 2022

ABSTRACT

Introduction
Peyronie's Disease (PD) is prevalent in approximately 7.1% of the general population. Current treatment approaches include medical therapy and surgical intervention, and intervention only occurs once the disease process has entered the chronic, stable phase. The only FDA-approved medical therapy involves use of intralesional collagenase clostridium histolyticum injection and surgical interventions include tunica albuginea plication, plaque excision without grafting, or placement of penile prothesis. Additional PD therapies are needed as current treatment modalities have limited efficacy and considerable side effects. Platelet-derived therapies have seen increased use across various specialties in medicine, especially in orthopedics, due to their potential ability in wound healing and tissue regeneration. As calcified scar plaques are frequently identified in PD patients, autologous platelet rich plasma (PRP) may prove to be a viable treatment for this patient population.

Objective
We reviewed an initial series of patients receiving PRP vs placebo for PD to assess safety and feasibility among men recruited in a double-blind placebo controlled single-center clinical trial.

Methods
We reviewed data for men recruited into the clinical trial treated with PRP vs placebo at our center from April 2021 to July 2021. Patients were observed immediately post-injection and at follow-up for complications and tolerability. Where applicable, International Index of Erectile Function (IIEF-5) scores were reviewed before and after injections for PD.

Results
We report data from the men who have completed 2 completed injections (PRP or placebo). No post-procedural minor adverse events were seen in any of the men. None of them reported adverse effects such as penile bruising, swelling, edema, allergy, penile fracture, or mild pain at injection site. No patients experienced complications at follow-up. No worsening curvature was observed in men completing pre/post evaluations.

Conclusions
PRP appears to be a safe and feasible treatment modality in patients with PD from our limited data accumulated thus far in our ongoing randomized placebo-controlled trial with PRP for PD. Our study is the first study in the USA accruing men with PRP for PD and believe that safety and efficacy data accumulated from our study will be important for patient counseling.

Disclosure
No
Le contrôle excessif dans le contexte des violences basées sur l’honneur au Québec : Analyse juridique et jurisprudentielle d’une violence genrée
Authors: Jimenez Estibaliz 
Published: April 2022

RésuméLe contrôle excessif est considéré par différents organismes communautaires et institutions du Québec comme une des représentations des violences basées sur l’honneur (VBH) au même titre que les mariages forcés, les mutilations génitales féminines (MGF) et les violences physiques ou psychologiques. En 2016, pour la première fois, le législateur québécois a ajouté le contrôle excessif à la liste des mauvais traitements psychologiques explicitement reconnus par la Loi sur la protection de la jeunesse (LPJ). Toutefois, aucune définition juridique, jurisprudentielle, politique ou même doctrinale du contrôle excessif n’accompagne cette reconnaissance juridique. Pourtant, il existe, sur le terrain et dans différentes décisions judiciaires, des situations où l’existence du contrôle excessif est reconnue par divers intervenants du système. L’objectif du présent article est d’appréhender le phénomène du contrôle excessif à partir, d’abord, d’un examen doctrinal et juridique, autant fédéral que provincial, concernant les VBH en général, et ensuite, d’une analyse jurisprudentielle des décisions de la Chambre de la Jeunesse de la Cour du Québec associées particulièrement au contrôle excessif. Le tout permettra de proposer une définition du contrôle excessif dans le contexte des VBH, dans le but de mieux identifier cette violence intrafamiliale spécifique et de mieux intervenir auprès des victimes et de leur famille.
Data mining and knowledge discovery in chemical processes: Effect of alternative processing techniques
Authors: Briceno-Mena Luis A. , Nnadili Miriam , Benton Michael G. , Romagnoli Jose A. 
Published: April 2022

AbstractData mining and knowledge discovery (DMKD) focuses on extracting useful information from data. In the chemical process industry, tasks such as process monitoring, fault detection, process control, optimization, etc., can be achieved using DMKD. However, the selection of the appropriate method for each step in the DMKD process, namely data cleaning, sampling, scaling, dimensionality reduction (DR), clustering, clustering analysis and data visualization to obtain meaningful insights is far from trivial. In this contribution, a computational environment (FastMan) is introduced and used to illustrate how method selection affects DMKD in chemical process data. Two case studies, using data from a simulated natural gas liquid plant and real data from an industrial pyrolysis unit, were conducted to demonstrate the applicability of these methodologies in real-life scenarios. Sampling and normalization methods were found to have a great impact on the quality of the DMKD results. Also, a neighbor graphs method for DR, t-distributed stochastic neighbor embedding, outperformed principal component analysis, a matrix factorization method frequently used in the chemical process industry for identifying both local and global changes.
Accumulation set of critical points of the multipliers in the quadratic family
Authors: FIRSOVA TANYA , GORBOVICKIS IGORS 
Published: April 2022

AbstractA parameter
$c_{0}\in {\mathbb {C}}$
in the family of quadratic polynomials
$f_{c}(z)=z^{2}+c$
is a critical point of a period n multiplier if the map
$f_{c_{0}}$
has a periodic orbit of period n, whose multiplier, viewed as a locally analytic function of c, has a vanishing derivative at
$c=c_{0}$
. We study the accumulation set
${\mathcal X}$
of the critical points of the multipliers as
$n\to \infty $
. This study complements the equidistribution result for the critical points of the multipliers that was previously obtained by the authors. In particular, in the current paper, we prove that the accumulation set
${\mathcal X}$
is bounded, connected, and contains the Mandelbrot set as a proper subset. We also provide a necessary and sufficient condition for a parameter outside of the Mandelbrot set to be contained in the accumulation set
${\mathcal X}$
and show that this condition is satisfied for an open set of parameters. Our condition is similar in flavor to one of the conditions that define the Mandelbrot set. As an application, we get that the function that sends c to the Hausdorff dimension of
$f_{c}$
does not have critical points outside of the accumulation set
${\mathcal X}$
.
Thermal conductivity of polar firn
Authors: Oster Simon E. , Albert Mary R. 
Published: April 2022

AbstractThe vast Greenland and Antarctic Ice Sheets are covered by many tens of meters of polar firn, which is snow that is years to centuries old and has experienced significant metamorphism. Both ice-sheet modeling and decoding satellite data require knowledge of the thermal conductivity of polar firn with depth, yet direct measurements are not available for depths below the top several meters. We present the first direct measurements of the effective thermal conductivity of polar firn over depths down to 48 m. A custom guarded hot plate has been designed and constructed, and validation of this device using materials of known thermal conductivity is presented. Using the validated device, measurements were made on firn core samples spanning depths from 4 to 48 m from an undisturbed site near the South Pole, Antarctica. Results show that the thermal conductivity of polar firn at South Pole increases with depth and with density. The thermal conductivity of polar firn from the surface to 48 m depth is well-explained as a function of density by the relationship kfirn(ρ) = 0.144 e0.00308·ρ and as a function of depth by the relationship kfirn(z) = 0.536 e0.0144·z. The associated thermal diffusivities range from 19.0 to 28.5 m2 a-1.
The FAST Ultra-Deep Survey (FUDS): Observational strategy, calibration and data reduction
Authors: Xi Hongwei , Peng Bo , Staveley-Smith Lister , For Bi-Qing , Liu Bin 
Published: April 2022

AbstractThe FAST Ultra-Deep Survey (FUDS) is a blind survey that aims for the direct detection of Hiin galaxies at redshifts$z<0.42$. The survey uses the multibeam receiver on the Five-hundred-metre Aperture Spherical Telescope (FAST) to map six regions, each of size$0.72\ \textrm{deg}^2$at high sensitivity (${\sim}50\,\mu \textrm{Jy}$) and high-frequency resolution (23 kHz). The survey will enable studies of the evolution of galaxies and their Hicontent with an eventual sample size of${\sim}1\,000$. We present the science goals, observing strategy, the effects of radio frequency interference at the FAST site, our mitigation strategies and the methods for calibration, data reduction and imaging as applied to initial data. The observations and reductions for the first field, FUDS0, are completed, with around 128 Higalaxies detected in a preliminary analysis. Example spectra are given in this paper, including a comparison with data from the overlapping GAL2577 field of Arecibo Ultra-Deep Survey.
Relocated tigers and relocated villagers: Ferality and human–animal entanglement in Indian conservation
Authors: Runacres Adam 
Published: April 2022

AbstractThis article will examine state intervention in the lives of tigers and people living in and around Panna Tiger Reserve in Madhya Pradesh, Central India. It explores how, over a decade after a reintroduction project rebuilt the tiger population from extinction and the central government launched a new compensation scheme to relocate villagers away from the national park, relocated tigers and not-yet relocated villagers resist and challenge conservation interventions to eradicate human life in Panna Tiger Reserve and (re)construct it as a wild tiger landscape. It will show how discourses of conservation and development that motivate state intervention seek to depoliticize and obfuscate programmes of control over human and tiger lives through their separation and purported ‘care’, contiguous with colonial policies and discursive practices that have intertwined the fate of wild animals and forest-dependent villagers in this part of India. In their feral subversions against these interventions, relocated tigers and not-yet relocated villagers expose the problematic contradictions and tensions that plague animal management, wildlife conservation, and rural development in India today. Based on 15 months of ethnographic fieldwork, the article draws on case studies and accounts from communities living around Panna Tiger Reserve to present alternatives to colonial and post-colonial discursive legitimizations of state intervention and control, revealing alternate understandings of the entanglement of humans and animals and the categories of ‘wild’ and ‘tame’.
Needs for nurses to provide spiritual care and their associated influencing factors among elderly inpatients with stroke in China: A cross-sectional quantitative study
Authors: Wang Zhangyi , Zhao Haomei , Zhu Yue , Zhang Siai , Xiao Luwei , Bao Haiqin , Wang Zhao , Wang Yue , Li Xuechun , Zhang Yajun , Pang Xiaoli 
Published: April 2022

AbstractObjectivesTo investigate the spiritual care needs and associated influencing factors among elderly inpatients with stroke, and to examine the correlations among spiritual care needs, spiritual well-being, self-perceived burden, self-transcendence, and social support.MethodsA cross-sectional quantitative design was implemented, and the STROBE Checklist was used as the foundation of the study. A convenience sample of 458 elderly inpatients with stroke was selected from three hospitals in China. The sociodemographic characteristics questionnaire, the Nurse Spiritual Therapeutics Scale, the Functional Assessment of Chronic Illness Therapy—Spiritual Well-being, the Self-Perceived Burden Scale, the Chinese Self-Transcendence Scale, and the Perceived Social Support Scale were used. Descriptive statistics, correlation, Student's t-test, ANOVA, non-parametric, and multiple linear regression analyses were used to analyze the data.ResultsThe total score of spiritual care needs was 29.82 ± 7.65. Spiritual care needs were positively correlated with spiritual well-being (r = 0.709, p < 0.01), self-transcendence (r = 0.710, p < 0.01), and social support (r = 0.691, p < 0.01), whereas being negatively correlated with self-perceived burden (r = −0.587, p < 0.01). Religious beliefs, educational level, residence place, disease course, spiritual well-being, self-perceived burden, self-transcendence, and social support were found to be the main influencing factors.Significance of resultsThe spiritual care needs were prevalent and moderate. It is suggested that nurses should enhance spiritual care knowledge and competence, take targeted spiritual care measures according to inpatients’ individual personality traits or characteristics and differences of patients, reduce their self-perceived burden and improve their spiritual well-being, self-transcendence and social support in multiple ways and levels, so as to meet their spiritual care needs to the greatest extent and enhance their spiritual comfort.
Improving the Calibration of the Swiss Plate Geophone Bedload Monitoring System by Filtering Out Seismic Signals From Extraneous Particle Impacts
Authors: Nicollier Tobias , Antoniazza Gilles , Rickenmann Dieter , Hartlieb Arnd , Kirchner James W. 
Published: April 2022

AbstractThe spatio‐temporal variability of bedload transport processes poses considerable challenges for bedload monitoring systems. One such system, the Swiss plate geophone (SPG), has been calibrated in several gravel‐bed streams using direct sampling techniques. The linear calibration coefficients linking the signal recorded by the SPG system to the transported bedload can vary between different monitoring stations by about a factor of six, for reasons that remain unclear. Recent controlled flume experiments allowed us to identify the grain‐size distribution of the transported bedload as a further site‐specific factor influencing the signal response of the SPG system, along with the flow velocity and the bed roughness. Additionally, impact tests performed at various field sites suggested that seismic waves generated by impacting particles can propagate over several plates of an SPG array, and thus potentially bias the bedload estimates. To gain an understanding of this phenomenon, we adapted a test flume by installing a partition wall to shield individual sensor plates from impacting particles. We show that the SPG system is sensitive to seismic waves that propagate from particle impacts on neighboring plates or on the concrete bed close to the sensors despite isolating elements. Based on this knowledge, we designed a filter method that uses time‐frequency information to identify and eliminate these “apparent” impacts. Finally, we apply the filter to four field calibration datasets and show that it significantly reduces site‐to‐site differences between calibration coefficients and enables the derivation of a single calibration curve for total bedload at all four sites.
GeoHealth Perspectives on Integrated, Coordinated, Open, Networked (ICON) Science
Authors: Barnard M. A. , Emani S. R. , Fortner S. K. , Haygood L. , Sun Q. , White‐Newsome J. L. , Zaitchik B. 
Published: April 2022

AbstractGeoHealth research both characterizes and predicts problems at the nexus of earth and human systems like climate change, pollution, and natural hazards. While GeoHealth excels in the area of integrated science, there is a need to improve coordinated and networked efforts to produce open science to enable environmental justice. There is a need to resource and empower frontline populations that are disproportionately marginalized by environmental injustice (i.e., the unequal protection from environmental harms and lack of access and meaningful engagement in decision making for a healthy environment; EPA, 2022, https://www.epa.gov/environmentaljustice). GeoHealth practice has the opportunity to advance environmental justice or the “fair treatment and meaningful involvement of all people regardless of race, color, national origin, or income” with respect to how research and collaboration of GeoHealth professionals supports the “development, implementation, and enforcement of environmental laws, regulations, and policies” that produce equal protection from environmental and health hazards and access to the decision making for a health environment (EPA, 2022, https://www.epa.gov/environmentaljustice). Here we highlight barriers and opportunities to apply an equity‐centered ICON framework to the field of GeoHealth to advance environmental justice and health equity.
Controls on the Boundary Between Thermally and Non‐Thermally Driven pCO2 Regimes in the South Pacific
Authors: Prend Channing J. , Hunt Jess M. , Mazloff Matthew R. , Gille Sarah T. , Talley Lynne D. 
Published: April 2022

AbstractRegional and temporal patterns of air–sea carbon exchange are strongly linked to the surface ocean partial pressure of carbon dioxide (pCO2), which varies with sea surface temperature (SST), salinity, dissolved inorganic carbon (DIC), and alkalinity. It is well‐known that temperature controls the pCO2 seasonal cycle in the subtropics, whereas DIC dominates at high latitudes. The balance of mechanisms governing the boundary between these regimes, however, are not well characterized due to lack of year‐round pCO2 data. Here, we use autonomous biogeochemical float measurements from the South Pacific to investigate the processes that control meridional variations in pCO2 seasonality. We find that the transition between pCO2 regimes is linked to the poleward decrease in SST seasonal cycle amplitude, which is closely associated with the northern boundary of deep winter mixed layers. Processes that determine the annual SST range are, therefore, central to the response of oceanic carbon uptake to anthropogenic forcing.
Deciphering the State of the Lower Crust and Upper Mantle With Multi‐Physics Inversion
Authors: Moorkamp Max 
Published: April 2022

AbstractThe composition of the lower crust is a key factor in understanding tectonic activity and deformation within the Earth. In particular, the presence or absence of melt or fluids has strong control on tectonic evolution. Multi‐physics inversion results from the western United States indicate that tectonic inheritance plays a much stronger role in determining the location of melt in the lower crust than previously thought. Even in a currently active area such as the Yellowstone Hotspot, the results suggest that fluid dominated structures and fluid free regions are located directly next to each other. This is incompatible with the commonly used model of recent tectonic activity as a main controlling factor for the presence of fluids or melt. These results have global implications for how geophysical models are interpreted and how they can be related to geodynamic simulations.
Satellite In Situ Electron Density Observations of the Midlatitude Storm Enhanced Density on the Noon Meridional Plane in the F Region During the 20 November 2003 Magnetic Storm
Authors: Lin Chin S. , Sutton Eric K. , Wang Wenbin , Cai Xuguang , Liu Guiping , Henney Carl J. , Cooke David L. 
Published: April 2022

AbstractIonospheric storm enhanced density (SED) has been extensively investigated using total electron content deduced from GPS ground and satellite‐borne receivers. However, dayside in situ electron density measurements have not been analyzed in detail for SEDs yet. We report in situ electron density measurements of a SED event in the Northern Hemisphere (NH) at the noon meridian plane measured by the Challenging Minisatellite Payload (CHAMP) polar‐orbiting satellite at about 390 km altitude during the 20 November 2003 magnetic storm. The CHAMP satellite measurements render rare documentation about the dayside SED's life cycle at a fixed magnetic local time (MLT) through multiple passes. Solar wind drivers triggered the SED onset and controlled its lifecycle through its growth and retreat phases. The SED electron density enhancement extended from the equatorial ionization anomaly to the noon cusp. The midlatitude electron density increased to a maximum at the end of the growth phase. Afterward, the dayside SED region retreated gradually to lower magnetic latitudes. The observations showed a hemisphere asymmetry, with the NH electron density exhibiting a more significant enhancement. The simulations using the Thermosphere Ionosphere Electrodynamic General Circulation model show a good agreement with the CHAMP observations. The simulations indicate that the dayside midlatitude electron density enhancement has a complicated dependence on vertical ion drift, neutral wind, magnetic latitude, MLT, and the height of the F2 layer. Finally, we discuss the notion of using the mean cross‐polar cap electric field as a proxy for assessing the effects of solar wind drivers on producing midlatitude electron density enhancement.
Seismic Traveltime Tomography of Southern California Using Poisson‐Voronoi Cells and 20 Years of Data
Authors: Fang Hongjian , White Malcolm C. A. , Lu Yang , Ben‐Zion Yehuda 
Published: April 2022

AbstractWe derive new, 3D, isotropic models of seismic compressional and shear wavespeeds, Vp and Vs, respectively, their ratio, Vp/Vs, and a catalog of relocated earthquakes for Southern California from more than 10 million P‐ and S‐wave arrivals associated with over 0.3 million earthquakes that occurred between 2000 and 2020. We augment high‐quality analyst‐reviewed phase arrival picks from the Southern California Earthquake Data Center with S‐wave arrival picks obtained with an automated algorithm, and we derive new wavespeed models via traveltime tomography formulated using Poisson‐Voronoi cells (Fang et al., 2020, https://doi.org/10.1785/0220190141). The results contribute to improved regional wavespeed models, particularly the Vp/Vs model, and absolute event locations. The obtained models correlate well with regional geological features and yield more accurate synthetic waveforms than other regional models do for waves with periods shorter than 5 s in much of the modeled region. The derived event catalog exhibits tighter spatial clustering than the standard regional catalog, thereby helping to characterize subsurface features of major faults. The regional 1D averaged Vp/Vs ratio shows high values at shallow depths, decreases to a minimum at about 10 km, then increases again at greater depths below 15 km. Deep seismicity correlates well with regions of Vp/Vs ratio lower than 1.75, which may indicate an increased brittle‐to‐ductile transition depth with an important influence on crustal mechanics. The new wavespeed models and seismic catalog can be useful for various studies including analyses of seismicity patterns and simulations of crustal deformation and ground motion.