bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developmental dyslexia biomarker detection with Quantitative electroencephalography (QEEG) data in children: feasibility, acceptability, economic impact
Authors: Eroglu Gunet , Köprülü Mertali , Karabacak Berdan 
Published: November 2022

INTRODUCTION
Developmental dyslexia awareness is not high in societies. Although 5-17% of the population is thought to be dyslexic in every global society, only 0.05 % of the population gets a formal diagnosis in Turkey. The financial situation of families of children with dyslexia is not enough to get an early diagnosis and investigate intensive remedial opportunities. Mobile apps have been used to diagnose health conditions in recent years. Worldwide solutions for dyslexia do not exist as the solutions were language-dependent. We need an easily reachable, affordable, language-independent, and worldwide acceptable biomarker detection app for dyslexia at schools because it potentially helps to prevent severe consequences through an early diagnosis that helps provide early intervention. No other research assessed the feasibility and acceptability of using this mobile app to detect dyslexia at home or school. Here we present a dyslexia biomarker detection app based on Z-scored Quantitative Electroencephalogram (QEEG) data that can be used at home or school and has accomplished a high accuracy rate in diagnosing dyslexia. The mobile app can be used at home by parents or teachers at school.

METHODS
We have collected data from 207 children (96 of them have dyslexia, 111 of them are typically developing) between 7-10 years old for 40 sessions on average. The data consists of the eyes-open resting state 2-minute QEEG data from 14 channels.

RESULTS
Using the Artificial Neural Network (ANN) machine learning method, children with dyslexia/ typically developing children (TDC) classification has been done with a high accuracy rate (98.8%). ANN yields the highest accuracy results with standardized QEEG data in the literature. A survey is created to assess the dyslexia biomarker detection app’s feasibility, acceptability, and economic impact. The results have shown that the biomarker detection app is found feasible and acceptable by families, however, it is found expensive to use at home as it includes the costly electroencephalography (EEG) headset.

CONCLUSION
In order for this biomarker detection method to be used extensively at home, EEG headset prices should become more affordable or this dyslexia biomarker detection method can be used at schools.
Dynamics of Volatility Spillover between Energy and Environmental, Social and Sustainable Indices
Authors: Babu Manivannan , Lourdesraj A. Antony , Hariharan C. , Jayapal Gayathri , Indhumathi G. , Sathya J. , Kathiravan Chinnadurai 
Published: November 2022

The purpose of this research was to examine the dynamics of volatility spillover between energy and environmental, social, and sustainable indices. COVID19 prompted the research to select April 2019 to March 2022 as a sample period, and the respective data (Daily Prices) of the Nifty Energy and Nifty ESG indices were obtained from the National Stock Exchange of India Limited. The outcomes of the study confirmed that the daily returns of Nifty Energy and Nifty 100 ESG indices were not normally distributed and reached stationarity at level difference. Further, the study employed GARCH Models such as ARCH, GARCH (1,1), and GARCH-M to determine conditional volatility, and it validated the ARCH influence on the daily returns of the Nifty Energy and Nifty 100 ESG, during the study period
On the Newen’s Person Model Theory
Authors: Ponomarev A. I. , Frolov K. G. 
Published: November 2022

Introduction. Strategies for understanding another person, which play an important role in social interactions, are focused on recognizing the mental states of the person who is under consideration. These various strategies require a general theoretical conceptualization. One of attempts of this kind of conceptualization is carried out by A. Neven's person model theory. This theory is a subject of our investigation and the aim of this study is to critically analyze A. Neven's person model theory and demonstrate its advantages and disadvantages in comparison with other approaches.Methodology and sources. A. Neven's approach is compared with three competing approaches: folk psychology theory, A. Goldman's simulation theory, and S. Gallagher's interaction theory. Conceptual analysis shows that these theories face a number of serious difficulties, which are discussed in article.Results and discussion. Based on our analysis, we conclude that none of these three theories can be accepted as universal. At the same time, A. Newen's person model theory suggests a multiple strategy for understanding another person and seeks to incorporate the merits of other theories. Thus, the main advantage of this approach is that it allows us to consider the process of understanding another person not as a predetermined one, but as a variable dynamic process. Conclusion. This approach allows considering as a person not only an adult, but also a collective of people, as well as artificial intelligence, which has a great importance for the further improvement of moral practices. At the same time, the person model theory is not devoid of weaknesses; however, when overcoming them, it is able to present the most complete mechanism for understanding the personality
Slow Science and Slow Education in a Digitalized University: an Anthropopractic Approach
Authors: Gorbunova Yu. A. , Boronikhina I. O. 
Published: November 2022

Introduction. The slow movement in universities is a reaction to the economic-centricity and commodification of higher education and science, the standardization and quantifiability of research and educational activities, the expansion of digital technologies` use in the generation and assimilation of knowledge, the imposition of the cult of speed on the academic and student communities. Rapid knowledge practices are becoming a trend in the context of digitalization of higher education. At the same time, the slow movement in Russian universities remains marginal and poorly institutionalized. The article analyzes the philosophical concepts that underlie the slow movement in universities and substantiates the importance of an anthropopractical approach to the study of slow science and slow education.Methodology and sources. The technocratic approach to the digitalization of higher education contributes to the spread of high-speed science and learning practices based on the reduction of knowledge to information, the growth of knowledge – to extension and cumulation, the cognitive motivation – to competition, greed and ambition. Turning to an anthropopractic approach allows us to overcome this reductionism. Slow science and slow education as anthropological practices are based on the desire of subjects of cognition for dialogue, reflection, improvisation and creative self-realization, self-organization and autodesign, intellectual enjoyment, sustainable, ecological coexistence. Digital technologies are only driving tools for this practice.Results and discussion. Slow practices in education and science are considered in this article, firstly, as an antithesis to the practices of posthumanism and futuro design, overcoming imperfect human nature and movement towards a posthuman with the help of nano-, bio-, information, cognitive and social technologies. Secondly, slow science and slow education as anthropological practices are opposed to managerial practices that form educational environments hostile to a person, the characteristic features of which are competition and hierarchy in the system “effective – ineffective”, “winners – losers”, “successful – catching up – lagging behind”. Conclusion. The authors see the optimal scenario for the transfer of slow practices to the sphere of higher education in Russia in achieving a balance between pragmatism, a shortterm policy and effectivenes, and a reflective position that ensures an anthropological orientation and sustainable development of modern universities.
Students’ Values of Various Training Profiles in the Digitalization of Society Context: Results of an Empirical Study
Authors: Deryugin P. P. , Bannova O. S. 
Published: November 2022

Introduction. The upcoming digitalization has a peculiar effect on the purposefulness of students' behavior, ensuring the transition to a new stage in the development of a postindustrial society. Social norms, values, and value orientations are subject to change. All this is formed into a new group of student digital values, which are shaped differently among students of various professional training profiles. These new phenomena involve the search for new methodological and methodological approaches to conducting empirical sociological research, the search for relevant approaches to measuring the digital values of students of various training profiles, and identifying special characteristics and meaningful features of these values.Methodology and sources. The research methodology is mixed, and is based on provisions about values and their specific forms of manifestation, particularly digital values (M. Weber, F. Znanetsky, T. Parsons, E. Durkheim, A. Toffler). The digital society is a new perspective, the nature of which is inconsistently consistent with some of the principles of the traditional approach to the study of values that have developed in theoretical concepts earlier. The concepts of modern authors were used, such as M. Tomasello, F. Warneken, R. Hogan, B.W. Roberts, E.F. Zeer, R. Kadakal, and Nguyen Hoang Huu. Results and discussion.The methodological approaches to the study of the values of the digital society as an object of study are generalized, in particular, the relevance of the system approach. The differences between the study of traditional values and the values of the digital society are shown, as a result of the analysis of which the accumulation of human capital by students with special (digital) characteristics could be considered as a main value of the digital society. Under these conditions, students of the humanitarian direction (journalists, sociologists) more often define for themselves value-goals as the most important values, and programming students define value-means as such. Conclusion. The study used a systematic approach to building a methodology for diagnosing digital values, which allows identifying the main value preferences of students of various training profiles. It is concluded that students of different training profiles understand the digital society differently, which implies different methodological approaches to the study and diagnosis of these values.
PENGARUH PIUTANG USAHA DAN UTANG USAHA TERHADAP ARUS KAS OPERASI MASA DEPAN PADA PERUSAHAAN SUB SEKTOR TRANSPORTASI YANG TERDAFTAR DI BURSA EFEK INDONESIA (BEI) TAHUN 2019-2021
Authors: Apriliani Ria , Martaseli Evi , Sudarma Ade 
Published: November 2022

Tujuan dari penelitian ini yaitu untuk menjelaskan pengaruh piutang usaha terhadap arus kas operasi masa depan, pengaruh utang usaha terhadap arus kas operasi masa depan, serta pengaruh piutang usaha dan utang usaha terhadap arus kas operasi masa depan. Subjek dalam penelitian ini yaitu perusahaan sub sektor transportasi yang terdaftar di Bursa Efek Indonesia (BEI) periode 2019-2021. Jumlah sampel yang digunakan dalam penelitian ini sebanyak 12 perusahaan dengan teknik random sampling. Metode penelitian yang digunakan peneliti dalam penelitian ini adalah metode asosiatif dengan pendekatan kuantitatif. Serta menggunakan uji asumsi klasik, analisis regresi linear berganda, dan uji hipotesis dengan SPSS 25.Hasil yang didapatkan dari penelitian ini yakni secara parsial piutang usaha memiliki dampak positif yang signifikan terhadap arus kas operasi di masa depan dengan nilai signifikansi 0,000, utang usaha memiliki dampak positif yang signifikan terhadap arus kas operasi di masa depan dengan nilai signifikansi 0,013, serta secara simultan piutang usaha dan utang usaha berpengaruh terhadap arus kas operasi masa depan dengan nilai signifikansi 0,000. Kata Kunci: Piutang Usaha, Utang Usaha, Arus Kas Operasi Masa Depan.
A Community and Hospital cAre Bundle to improve the medical treatment of severe cLaudIcation and critical limb iSchaemia (CHABLIS)
Authors: Watson Emma , Bridgwood Bernadeta , Saha Prakash , Bown Matthew , Benson Ruth , Lawrence Vanessa , Le Boutillier Clair , Lasserson Daniel , Messeder Sarah , Saratzis Athanasios 
Published: November 2022

Background: Patients with peripheral artery disease (PAD) often do not receive optimal best medical therapy (BMT). Through interaction with patients and haealthcare-professionals (HCPs) we developed the LEaflet Gp letter Structured checklist (LEGS) complex clinical intervention to support HCPs provide guideline-compliant PAD BMT. Methods: This was a prospective multicentre study assessing the feasibility and fidelity of delivering the LEGS intervention in primary and secondary care over 6 months. Intervention fidelity was scored based on the proportion of intervention components used correctly at discharge, 30 days, and 6 months. Results: Overall, 129 individuals were screened and 120 took part (33% female, 74% with chronic limb threatening ischaemia; 93% recruitment rate). Of those, 118 (98% retention rate) completed follow-up. Mean intervention fidelity score at discharge (primary outcome measure) was 63% [95% Confidence Interval (CI): 39-68%, SD: 5%], exceeding the success criteria set at 60% by a panel of HCPs and patients. This, however, declined to 51% at 6 months. Eight patients (6.7%) died (all cardiovascular deaths), 4 (3.3%) had a major lower limb amputation, 12 (10%) had a cardiovascular event, and 13 (11%) were admitted due to limb ischaemia at 6 months. Incomplete lipid therapy prescriptions and LEGS intervention documents not received by primary care CHPs were the most common reasons for not complying with the LEGS intervention. Conclusion: The LEGS intervention can be delivered in PAD care pathways across different hospitals, primary, and community healthcare settings with acceptable fidelity, to streamline and improve PAD BMT short and medium term.
Determinan Kegagalan Pemberian Asi Eksklusif Pada Ibu Menyusui Di Wilayah Puskesmas Banda Raya Kota Banda Aceh
Authors: Oktaviyana Cut , Pratama Urip , Igbal Muhammad , Fitriya Ika Rahmi , Adha Mutiara Nurul , Nelly Zia Novia 
Published: November 2022

Capaian pemberian ASI eksklusif di kota Banda Aceh berada di bawah capaian nasional 80%, yaitu 59% tahun 2020 sehingga jauh dari capaian program Sustainable Development Goals (SDGs). ASI eksklusif tidak dijalankan menyebabkan berbagai masalah kesehatan bayi terutama pada pertumbuhan, perkembangan bayi, imunologis, psikologis serta ekonomi orang tua bayi. Cakupan pemberian ASI terendah berada di wilayah Puskesmas Banda Raya (34,2%). Rendahnya capaian menunjukkan program ASI eksklusif belum maksimal. Beberapa faktor seperti pengetahuan, dukungan sosial, Breastfeeding Self-Efficacy (BSE) serta sosial budaya adalah hal yang dikaitkan dengan ASI eksklusif. Penelitian bertujuan mengetahui hubungan determinan kegagalan pemberian ASI eksklusif di wilayah kerja Puskesmas Banda Raya Kota Banda Aceh. Penelitian cross sectional dengan 67 sample ibu menyusui usia bayi 6 – 11 bulan dengan kondisi tanpa riwayat penyakit kongenital dan kronis serta menggunakan purposive sampling. Data dikumpulkan melalui pembagian kuesioner tanggal 8 – 12 Agustus 2022 di wilayah kerja Puskesmas Banda Raya. Hasil analisis uji regresi logistik sederhana bahwa ibu memiliki pengetahuan baik berpeluang 43% (OR 0,43) menjalankan ASI eksklsuif. Ibu memiliki BSE tinggi berpeluang 5,11 kali (OR 5,11) tetap memberikan ASI eksklusif. Ibu dengan sosial budaya yang mendukung berpeluang 18% (OR 0,18) memberikan ASI eksklusif. Variabel tersebut menjadi penentu kegagalan ibu untuk memberikan ASI eksklusif. Promosi kesehatan ASI eksklusif perlu ditingkatkan kepada orang tua bayi, keluarga serta tenaga kesehatan terkait.
ADAPTASI SOSIAL DALAM MASYARAKAT MULTIKULTURAL ERA KETERBUKAAN INFORMASI
Authors: Ramadani Helsi , Indraddin Indraddin , Azwar Azwar 
Published: November 2022

Transmigration is one of the government programs in the context of solving population problems which was reopened in 2016 in Sijunjung Regency, namely Kenagarian Padang Tarok. Consisting of ethnic Javanese and ethnic Minangkabau. Given the two different ethnic backgrounds, it is necessary to make an adaptation. The purpose of this study was to determine social adaptation in a multicultural society in the era of information disclosure. This study uses the theory of Arnold Toynbee Challenge and Response. Qualitative method. Data collection with observation and in-depth interview techniques. Informants were taken using purposive sampling technique. Based on the results of the study, it was concluded that the challenges of the Padang Tarok transmigrant community were in the form of language differences, a feeling of being ignored which gave rise to negative sentiments, the emergence of camps and groups between blocks, job choices. and the response to these challenges is to apply Indonesian as a means of communication, to apply an attitude of mutual openness and sharing, to participate in community activities, and to gain gold as a new form of work. The people of Padang Tarok live in a high sense of respect and have an attitude of helping each other.AbstrakTransmigrasi merupakan salah satu program pemerintah dalam rangka pemecahan masalah kependudukan yang dibuka kembali pada tahun 2016 di Kabupaten Sijunjung yaitu Kenagarian Padang Tarok. Terdiri dari Etnis Jawa dan Etnis Minangkabau. Mengingat kedua latar belakang etnis berbeda maka perlu dilakukan sebuah adaptasi. Tujuan penelitian ini adalah Mengetahui adaptasi sosial dalam masyarakat multikultural era keterbukaan informasi. Penelitian ini menggunakan teori Arnold Toynbee Challenge and Respons. Metode kualitatif. Pengumpulan data dengan teknik observasi dan wawancara mendalam. Pengambilan informan menggunakan teknik Purposive sampling. Berdasarkan hasil penelitian disimpulkan bahwa tantangan masyarakat transmigran Padang Tarok berupa Perbedaan bahasa, timbul rasa tidak dipedulikan yang memunculkan sentimen negatif, munculnya kubu-kubu dan kelompok antar blok, pilihan pekerjaan. serta respon dari tantangan tersebut adalah menerapkan Bahasa Indonesia sebagai alat komunikasi, menerapkan sikap saling terbuka dan saling berbagi, berpatisipasi dalam kegiatan masyarakat, dan mendulang emas sebgai bentuk pekerjaan baru. Masyarakat Padang Tarok hidup dalam menerapkan rasa harga-menghargai yang tinggi dan memiliki sikap saling tolong-menolong antar sesama.
The impact of early life maternal deprivation on the perineuronal nets in the prefrontal cortex and hippocampus of young adult rats
Authors: Jakovljevic Ana , Agatonovic Gorana , Aleksic Dubravka , Aksic Milan , Reiss Gebhard , Förster Eckart , Stamatakis Antonios , Jakovcevski Igor , Poleksic Joko 
Published: November 2022

Early life stress negatively impacts brain development and affects structure and function of parvalbumin immunopositive (PV+) inhibitory neurons. Main regulators of PV+ interneurons activity and plasticity are perineuronal nets (PNNs), an extracellular matrix formation that enwraps PV+ interneurons mainly in the neocortex and hippocampus. To experimentally address the impact of early life stress on the PNNs and PV+ interneurons in the medial prefrontal cortex and dorsal hippocampus in rats, we employed a 24 h maternal deprivation protocol. We show that maternal deprivation in the medial prefrontal cortex of adult rats caused a decrease in density of overall PNNs and PNNs that enwrap PV+ interneurons in the rostral cingulate cortex. Furthermore, a staining intensity decrease of overall PNNs and PNN+/PV+ cells was found in the prelimbic cortex. Finally, a decrease in both intensity and density of overall PNNs and PNNs surrounding PV+ cells was observed in the infralimbic cortex, together with increase in the intensity of VGAT inhibitory puncta. Surprisingly, maternal deprivation did not cause any changes in the density of PV+ interneurons in the mPFC, neither had it affected PNNs and PV+ interneurons in the hippocampus. Taken together, our findings indicate that PNNs, specifically the ones enwrapping PV+ interneurons in the medial prefrontal cortex, are affected by early life stress.
Succinate aggravates intestinal injury in mice with necrotizing enterocolitis
Authors: Yan Xiao-Lin , Liu Xiao-Chen , Zhang Yu-Ni , Du Ting-Ting , Ai Qing , Gao Xiong , Yang Jing-Li , Bao Lei , Li Lu-Quan 
Published: November 2022

BackgroundNecrotizing enterocolitis (NEC) is the most prevalent gastrointestinal disorder that predominantly threatens preterm newborns. Succinate is an emerging metabolic signaling molecule that was recently studied in relation to the regulation of intestinal immunity and homeostasis. We aimed to investigate the relationship between NEC and gut luminal succinate and preliminarily explored the effect of succinate on NEC pathogenesis.MethodsFecal samples from human neonates and mouse pups were analyzed by HPLC – MS/MS and 16S rRNA gene sequencing. C57BL/6 mice were randomly divided into four groups: control, NEC, Lsuc, and Hsuc. The mortality, weight gain, and intestinal pathological changes in four mouse groups were observed. Inflammatory cytokines and markers of macrophages were identified by quantitative real-time PCR. Succinate receptor 1 (SUCNR1) localization was visualized by immunohistochemistry. The protein levels of SUCNR1 and hypoxia-inducible factor 1a (HIF-1a) were quantified by western blotting.ResultsThe levels of succinate in feces from NEC patients were higher than those in feces from non-NEC patients (P &lt;0.05). In the murine models, succinate levels in intestinal content samples were also higher in the NEC group than in the control group (P &lt;0.05). The change in succinate level was closely related to intestinal flora composition. In samples from human neonates, relative to the control group, the NEC group showed a higher abundance of Enterobacteriaceae and a lower abundance of Lactobacillaceae and Lactobacillus (P &lt;0.05). In the murine models, relative to the control group, increased abundance was observed for Clostridiaceae, Enterococcaceae, Clostridium_sensu_stricto_1, and Enterococcus, whereas decreased abundance was observed for Lactobacillaceae and Lactobacillus (P &lt;0.05). Increased succinate levels prevented mice from gaining weight, damaged their intestines, and increased their mortality; upregulated the gene expression of interleukin-1β (IL-1β), IL-6, IL-18 and tumor necrosis factor (TNF); and downregulated the gene expression of IL-10 and transforming growth factor (TGF)-β. Exogenous succinic acid increased inducible nitric oxide synthase (iNOS) gene expression but decreased Arginase-1 (Arg1) gene expression; and increased the protein expression of SUCNR1 and HIF-1a.ConclusionSuccinate plays an important role in the development of necrotizing enterocolitis severity, and the activation of the HIF-1a signaling pathway may lead to disease progression.