bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional Resistance Training Improves Thigh Muscle Strength after ACL Reconstruction: A Randomized Clinical Trial
Authors: PALMIERI-SMITH RIANN M. , BROWN SCOTT R. , WOJTYS EDWARD M. , KRISHNAN CHANDRAMOULI 
Published: May 2022

ABSTRACT

Purpose
Quadriceps weakness is common after anterior cruciate ligament (ACL) reconstruction, resulting in prolonged disability and increased risk for reinjury and osteoarthritis. Functional resistance training (FRT) combines resistance training with task-specific training and may prove beneficial in restoring quadriceps strength. The primary purpose of this study was to determine if a walking-specific FRT program (e.g., resisted walking) improves knee strength in individuals after ACL reconstruction.

Methods
Thirty participants were randomized into one of three groups: 1) FRT with a customized knee BRACE applied to the ACL leg, 2) FRT with elastic BAND tethered to the ankle of the ACL leg, or 3) a TARGET MATCH condition where no resistance was externally applied. Participants in all groups received training while walking on a treadmill 2–3 times per week for 8 wk. Isometric knee extension and flexion strength were measured before the start of the intervention, after the intervention (POST), and 8 wk after intervention completion (POST-2).

Results
The BRACE group had greater knee extensor strength compared with the TARGET MATCH group at POST and POST-2 (P < 0.05). The BRACE group had greater knee flexor strength than the TARGET MATCH group at POST and POST-2 (P < 0.05) and the BAND group at POST (P < 0.05).

Conclusions
FRT applied via a customized knee brace results in improvements in knee extensor and flexor strength after ACL reconstruction. FRT is a beneficial adjuvant to ACL rehabilitation and leads to better strength compared with standard of care.
Current practices of physiotherapists in Switzerland regarding fall risk-assessment for community-dwelling older adults: A national cross-sectional survey
Authors: Duc Morgane , Mittaz Hager Anne-Gabrielle , Zemp Damiano , Roulet Guillaume , Bridel Alice , Hilfiker Roger 
Published: May 2022

Background: Falls can strongly impact older people’s quality of life, health, and lifestyle. Multifactorial assessment can determine an individual’s risk of falling as the first step for fall prevention intervention. Physiotherapists have an essential role to play in assessing fall risk by older adults living in the community. In the absence of published data on this topic in Switzerland, this study investigated the current practices of physiotherapists to determine whether those are in line with recommendations. Methods: An anonymous cross-sectional survey was undertaken among physiotherapists practising in Switzerland between the 21st of November and the 31st of December 2020. A priori and exploratory hypotheses were tested. Responses to open-ended questions were grouped into themes for analysis. Results: A total of 938 questionnaires from all three language regions of Switzerland was analysed. Participants worked in different settings, with a higher representation of private practice self-employees (56%). Standardised fall risk assessments or instruments were used by 580 (62%) participants, while 235 (25%) preferred subjective assessment of fall risk only. Differences in fall risk assessment were observed according to the workplace setting (adjusted OR 1.93, 95% CI 1.37 to 2.7) and education level (trend test, p<0.001). The standardised assessments most frequently employed were the Berg Balance Scale (57.5%), the Timed-Up-and-Go (56.5%) and the Tinetti Balance Assessment tool (46.7%). Risk factors for falls were frequently queried, particularly history of falls (88.3%), home hazards (84.1%), and functional ability (81%). Technical resources (39.8%), knowledge (30.3%), and time (22.2%) were common barriers to implement a systematic fall risk assessment. Conclusions: This study provides an overview of the current practices of physiotherapists in Switzerland in fall risk assessment. There is still room to optimise the standardisation and systematisation of this assessment to implement a best practice strategy and prevent avoidable falls.
MindKind: A mixed-methods protocol for the feasibility of global digital mental health studies in young people
Authors:   The MindKind Consortium
Published: May 2022

Background: While an estimated 14-20% of young adults experience mental health conditions worldwide, the best strategies for prevention and management are not fully understood. The ubiquity of smartphone use among young people makes them excellent candidates for collecting data about lived experiences and their relationships to mental health. However, not much is known about the factors affecting young peoples’ willingness to share information about their mental health. Objective: We aim to understand the data governance and engagement strategies influencing young peoples’ (aged 16-24) participation in app-based studies of mental health. We hypothesize that willingness to participate in research is influenced by involvement in how their data is collected, shared, and used. Methods: Here, we describe the MindKind Study, which employs mixed methods to understand the feasibility of global, smartphone-based studies of youth mental health. A pilot 12-week app-based substudy will query participants’ willingness to engage with remote mental health studies. Participants will be randomized into one of four different data governance models designed to understand their preferences, as well as the acceptability of models that allow them more or less control over how their data are accessed and used. Enrolees will receive one of two different engagement strategies. A companion qualitative study will employ a deliberative democracy approach to examine the preferences, concerns and expectations of young people, with respect to remote mental health research. We also detail our engagement with young people as co-researchers in this study. This pilot study is being conducted in India, South Africa and the United Kingdom. Conclusions: This study is expected to generate new insights into the feasibility of, and best practices for, remote smartphone-based studies of mental health in youth and represents an important step toward understanding which approaches could help people better manage their mental health.
Nurse staffing and patient care outcomes: protocol for an umbrella review to identify evidence gaps for low and middle-income countries in global literature
Authors: Imam Abdulazeez , Obiesie Sopuruchukwu , Aluvaala Jalemba , Maina Michuki , Gathara David , English Mike 
Published: May 2022

Background: Adequate staffing is key to the delivery of nursing care and thus to improved inpatient and health service outcomes. Several systematic reviews have addressed the relationship between nurse staffing and these outcomes. Most primary studies within each systematic review are likely to be from high-income countries which have different practice contexts to low and middle-income countries (LMICs), although this has not been formally examined. We propose conducting an umbrella review to characterise the existing evidence linking nurse staffing to key outcomes and explicitly aim to identify evidence gaps in nurse staffing research in LMICs. Methods and analysis: This protocol was developed using the Preferred Reporting Items for Systematic Reviews and Meta-analysis Protocols (PRISMA-P). Literature searching will be conducted across Ovid Medline, Embase and EBSCO Cumulative Index to Nursing and Allied Health Literature (CINAHL) databases. Two independent reviewers will conduct searching and data abstraction and discordance will be handled by discussion between both parties. The risk of bias of the individual studies will be performed using the AMSTAR-2. Ethics and dissemination: Ethical permission is not required for this review as we will make use of already published data. We aim to publish the findings of our review in peer-reviewed journals. PROSPERO registration number: CRD42021286908
Obesity treatment - overview of pharmacological and surgical methods
Authors: Osiak Joanna , Mikut Karolina , Wijata Aleksandra , Kędziora-Kornatowska Kornelia 
Published: May 2022

Introduction and purpose of the work: Obesity is a chronic disease that leads to many complications. Almost a third of the world's population is now classified as overweight or obese. This is a huge global problem. The base of treatment is diet and physical activity, but fortunately nowadays we also have pharmacological and surgical treatment - which are increasingly used. The aim of this study is to draw attention to obesity disease which may lead to serious complications and compare available pharmacological and surgical treatment.
State of knowledge (brief description): Treating obesity is a difficult and often multidisciplinary challenge. Currently many drugs with different mechanisms and different efficiencies has been approved for treatment. All of them show efficiency, but the available studies show that surgical treatment produces better results than pharmacological treatment.
Summary: We currently have a huge range of obesity treatment options available. Surgical treatment produces better results than pharmacological treatment. Nevertheless, not every patient qualifies for bariatric surgery. Pharmacological methods are also effective. The treatment method should be individually selected for the patient.
Impact of racial disparities and insurance status in patients with bone sarcomas in the USA
Authors: Hu Xianglin , Fujiwara Tomohiro , Houdek Matthew T. , Chen Lingxiao , Huang Wending , Sun Zhengwang , Sun Yangbai , Yan Wangjun 
Published: May 2022

Aims Socioeconomic and racial disparities have been recognized as impacting the care of patients with cancer, however there are a lack of data examining the impact of these disparities on patients with bone sarcoma. The purpose of this study was to examine socioeconomic and racial disparities that impact the oncological outcomes of patients with bone sarcoma. Methods We reviewed 4,739 patients diagnosed with primary bone sarcomas from the Surveillance, Epidemiology and End Results (SEER) registry between 2007 and 2015. We examined the impact of race and insurance status associated with the presence of metastatic disease at diagnosis, treatment outcome, and overall survival (OS). Results Patients with Medicaid (odds ratio (OR) 1.41; 95% confidence interval (CI) 1.15 to 1.72) and uninsured patients (OR 1.90; 95% CI 1.26 to 2.86) had higher risks of metastatic disease at diagnosis compared to patients with health insurance. Compared to White patients, Black (OR 0.63, 95% CI 0.47 to 0.85) and Asian/Pacific Islander (OR 0.65, 95% CI 0.46 to 0.91) were less likely to undergo surgery. In addition, Black patients were less likely to receive chemotherapy (OR 0.67, 95% CI 0.49 to 0.91) compared to White patients. In patients with chondrosarcoma, those with Medicaid had worse OS compared to patients with insurance (hazard ratio (HR) 1.65, 95% CI 1.06 to 2.56). Conclusion In patients with a bone sarcoma, the cancer stage at diagnosis varied based on insurance status, and racial disparities were identified in treatment. Further studies are needed to identify modifiable factors which can mitigate socioeconomic and racial disparities found in patients with bone sarcomas. Cite this article: Bone Joint Res 2022;11(5):278–291.
Study on Water Regulation of Yong’an River Basin Based on Ecological Flow Guarantee
Authors: Guo Huifang , Yin Fangfang , Ma Haibo , Tian Chuanchong , Zhang Shixia 
Published: May 2022

Water resources are the necessary guarantee to support the development of human society and one of the most important resources to maintain the health and stability of the ecological environment. With the gradual increase of China’s population and the gradual increase of water consumption for industry, life and agriculture, the water consumption for ecological environment can not be met. As a result, some rivers have dried up, biological habitat has been lost and species diversity has been reduced. Therefore, how to ensure the river ecological flow is a very urgent problem to be solved. This paper selects Yong’an River Basin as the research object. Yong’an river is a mountainous river with the characteristics of uneven distribution of natural runoff throughout the year and seasonal water shortage. At present, the ecological flow demand of the river has not been considered in the reservoir operation. In this paper, four different scheduling schemes are set up according to the two constraints of ecological base flow and target ecological flow. Finally, the reservoir group operation scheme with better water supply assurance rate and ecological flow assurance rate is determined.
Laser radius measurement method based on the amplitude jump of a
thermal wave
Authors: Hu Dongjin , Qin Xunpeng , Hu Zeqi , Zeng Yan , Ji Feilong 
Published: May 2022

The laser radius should be calculated with high precision when analyzing the
characteristics of a Lamb wave excited by a laser in a thin plate.
However, traditional methods for measuring the radius of a laser beam
are complex. The paper aims to propose a novel convenient method, to
the best of our knowledge, for measuring the radius of a laser
ultrasonic beam. A laser interferometer (receiving laser) is used to
receive ultrasonic signals excited by the laser to be measured
(exciting laser) on the surface of a test block. Considering the
characteristics represented by the thermal wave, positions where the
receiving beam contacts and separates from the exciting beam are
determined, and the spot of the radius is calculated by corresponding
geometric relations. Experiments show that the accuracy of the
proposed method is in the order of magnitude of 0.01 mm, and the
relative errors of experimental data are within 2%. This paper
provides an alternative method for the measurement of the laser beam
radius and has great significance for the application of laser
ultrasonic detection in the thin plate and the calculation and
analysis of the dispersion curve.
Establishing a framework towards monitoring HCV microelimination among men who have sex with men living with HIV in Germany: A modeling analysis
Authors: Marquez Lara K. , Ingiliz Patrick , Boesecke Christoph , Krznaric Ivanka , Schewe Knud , Lutz Thomas , Mauss Stefan , Christensen Stefan , Rockstroh Jürgen K. , Jain Sonia , He Feng , Wertheim Joel O. , Martin Natasha K. 
Published: May 2022

Background
Prior to direct-acting antivirals (DAAs), HCV incidence rose among men who have sex with men (MSM) living with HIV infection in Germany despite high hepatitis C virus (HCV) treatment rates. We establish a HCV elimination modeling framework to evaluate whether existing treatment rates can achieve the World Health Organization (WHO) incidence target among MSM living with HIV in Germany.

Methods
To evaluate progress towards HCV elimination in Germany, we adapted a previously published HCV transmission model among MSM living with diagnosed HIV. We modelled HCV incidence and prevalence until 2030 (relative to 2015) under existing treatment and DAA scale-up and explored potential impacts of disruptions in treatment and behavioral risk reduction due to the COVID-19 pandemic.

Results
Continuing current treatment rates will result in stable HCV incidence among MSM living with HIV in Germany between 2015–2030. The WHO HCV incidence target is achievable under DAA scale-up to 100% treatment combined with treatment of those previously diagnosed and untreated (at a rate of 15%/year) and would result in greater reductions with early treatment (3 vs 6 months) reducing incidence from 4.0/100person-years to 0.8/100person-years by 2030. A 12-month disruption to HCV treatment (20% reduction) and risk behaviors (25%,50%,75% reduction) during the COVID-19 pandemic would result in a 15% relative increase in total HCV incidence in 2030 compared to that expected under the status quo.

Conclusions
HCV elimination among MSM living with HIV in Germany requires further DAA scale-up among those newly diagnosed combined with efforts to treat those previously diagnosed but untreated. Prospective monitoring will establish whether Germany is on track for HCV microelimination.
Effectiveness of a home telemonitoring program for patients with chronic obstructive pulmonary disease in Germany: Evidence from the first three years
Authors: Hofer Florian , Schreyögg Jonas , Stargardt Tom 
Published: May 2022

Introduction
Chronic obstructive pulmonary disease (COPD) affects more than 6 million people in Germany. Monitoring the vital parameters of COPD patients remotely through telemonitoring may help doctors and patients prevent and treat acute exacerbations of COPD, improving patients’ quality of life and saving costs for the statutory health insurance system.

Objective
To evaluate the effects from October 2012 until December 2015 of a structured home telemonitoring program implemented by a statutory health insurer in Germany.

Methods
We conducted a retrospective cohort study using administrative data. After building a balanced control group using Entropy Balancing, we calculated difference-in-difference estimators to account for time-invariant heterogeneity. We estimated differences in mortality rates using Cox regression and conducted subgroup and sensitivity analyses to check the robustness of the base case results. We observed each patient in the program for up to 3 years depending on his or her time of enrolment.

Results
Among patients in the telemonitoring cohort, we observed significantly higher inpatient costs due to COPD (€524.2, p<0,05; €434.6, p<0.05) and outpatient costs (102.5, p<0.01; 78.8 p<0.05) during the first two years of the program. Additional cost categories were significantly increased during the first year of telemonitoring. We also observed a significantly higher number of drug prescriptions during all three years of the observation period (2.0500, p < 0.05; 0.7260, p < 0.05; 3.3170, p < 0.01) and a higher number of outpatient contacts during the first two years (0.945, p<0.01, 0.683, p<0.05). Furthermore, we found significantly improved survival rates for participants in the telemonitoring program (HR 0.68, p<0.001).

Conclusion
On one hand, telemonitoring was associated with higher health care expenditures, especially in the first year of the program. For example, we were able to identify a statistically significant increase in inpatient costs due to COPD, outpatient contacts and drug prescriptions among individuals participating in the telemonitoring program. On the other hand, the telemonitoring program was accompanied by a survival benefit, which might be related to higher adherence rates, more intense treatment, or an improved understanding of COPD among these patients.
Development and initial validation of the Japanese healthy work environment assessment tool for critical care settings
Authors: Kitayama Mio , Unoki Takeshi , Matsuda Yui , Matsuishi Yujiro , Kawai Yusuke , Iida Yasuo , Teramoto Mio , Tatsuno Junko , Hamamoto Miya 
Published: May 2022

Aim
This study aims to translate the Healthy Work Environment Assessment Tool (HWE-AT) into Japanese and evaluate its validity and reliability.

Design and methods
The authors followed the guidelines for scale translation, adaptation, and validation in cross-cultural healthcare research. After translation and back-translation, a series of pilot studies were conducted to assess comprehensibility. Subsequently, an expert panel established the content validity. Content validity was calculated using the content validity index (CVI). Finally, we verified the construct validity and calculated the test-retest reliability.

Results
The updated HWE-AT achieved sufficient comprehensibility after conducting the two pilot tests. Content validity was calculated using the scale-level CVI/average and all the items were 1.00. The content validity indices CFI and RMSEA were 0.918 and 0.082, respectively. Intraclass correlation coefficients for all dimensions ranged from 0.618 to 0.903, indicating acceptable test-retest reliability. Our findings suggest that the Japanese version of the HWE-AT has good validity and reliability.
Prognostic value of upper respiratory tract microbes in children presenting to primary care with respiratory infections: A prospective cohort study
Authors: McGeoch Luke J. , Thornton Hannah V. , Blair Peter S. , Christensen Hannah , Turner Nicholas L. , Muir Peter , Vipond Barry , Redmond Niamh M. , Turnbull Sophie , Hay Alastair D. 
Published: May 2022

Background
The association between upper respiratory tract microbial positivity and illness prognosis in children is unclear. This impedes clinical decision-making and means the utility of upper respiratory tract microbial point-of-care tests remains unknown. We investigated for relationships between pharyngeal microbes and symptom severity in children with suspected respiratory tract infection (RTI).

Methods
Baseline characteristics and pharyngeal swabs were collected from 2,296 children presenting to 58 general practices in Bristol, UK with acute cough and suspected RTI between 2011–2013. Post-consultation, parents recorded the severity of six RTI symptoms on a 0–6 scale daily for ≤28 days. We used multivariable hurdle regression, adjusting for clinical characteristics, antibiotics and other microbes, to investigate associations between respiratory microbes and mean symptom severity on days 2–4 post-presentation.

Results
Overall, 1,317 (57%) children with complete baseline, microbiological and symptom data were included. Baseline characteristics were similar in included participants and those lacking microbiological data. At least one virus was detected in 869 (66%) children, and at least one bacterium in 783 (60%). Compared to children with no virus detected (mean symptom severity score 1.52), adjusted mean symptom severity was 0.26 points higher in those testing positive for at least one virus (95% CI 0.15 to 0.38, p<0.001); and was also higher in those with detected Influenza B (0.44, 0.15 to 0.72, p = 0.003); RSV (0.41, 0.20 to 0.60, p<0.001); and Influenza A (0.25, -0.01 to 0.51, p = 0.059). Children positive for Enterovirus had a lower adjusted mean symptom severity (-0.24, -0.43 to -0.05, p = 0.013). Children with detected Bordetella pertussis (0.40, 0.00 to 0.79, p = 0.049) and those with detected Moraxella catarrhalis (-0.76, -1.06 to -0.45, p<0.001) respectively had higher and lower mean symptom severity compared to children without these bacteria.

Conclusions
There is a potential role for upper respiratory tract microbiological point-of-care tests in determining the prognosis of childhood RTIs.