bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unique decompositions into w-ideals for strong Mori domains
Authors: Ay Saylam Başak , Gürbüz Ezgi , Hamdi Haleh 
Published: August 2022

A commutative ring [Formula: see text] has the unique decomposition into ideals (UDI) property if, for any [Formula: see text]-module that decomposes into a finite direct sum of indecomposable ideals, this decomposition is unique up to the order and isomorphism classes of the indecomposable ideals. In [P. Goeters and B. Olberding, Unique decomposition into ideals for Noetherian domains, J. Pure Appl. Algebra 165 (2001) 169–182], the UDI property has been characterized for Noetherian integral domains. In this paper, we aim to study the UDI-like property for strong Mori domains; domains satisfying the ascending chain condition on [Formula: see text]-ideals.
Covariance kernel of linear spectral statistics for half-heavy tailed Wigner matrices
Authors: Lodhia Asad , Maltsev Anna 
Published: August 2022

In this paper, we analyze the covariance kernel of the Gaussian process that arises as the limit of fluctuations of linear spectral statistics for Wigner matrices with a few moments. More precisely, the process we study here corresponds to Hermitian matrices with independent entries that have [Formula: see text] moments for [Formula: see text]. We obtain a closed form [Formula: see text]-dependent expression for the covariance of the limiting process resulting from fluctuations of the Stieltjes transform by explicitly integrating the known double Laplace transform integral formula obtained in [F. Benaych-Georges and A. Maltsev, Fluctuations of linear statistics of half-heavy-tailed random matrices, Stochastic Process. Appl. 126(11) (2016) 3331–3352]. We then express the covariance as an integral kernel acting on bounded continuous test functions. The resulting formulation allows us to offer a heuristic interpretation of the impact the typical large eigenvalues of this matrix ensemble have on the covariance structure.
Effervescent Progesterone Vaginal Tablet Mono-Administration Demonstrated Comparable Pregnancy Rate Across the Different Serum Progesterone Levels on the Day of Embryo Transfer in SHIFT Study
Authors: Fujiwara Toshihiro , Kusumi Maki , Utsunomiya Takafumi , Nomiyama Mari , Yanagida Kaoru , Watanabe Yoshitsugu , Yamaguchi Yukiharu , Tanaka Atsushi 
Published: August 2022

Background: Hormone replacement (HR)-frozen thawed embryo transfer (FET) is preferentially used in Japan. HR-FET needs supplementation of progesterone, but there are few data about the efficacy and safety of vaginal progesterone tablet. The aim of this study is to investigate the efficacy of vaginal progesterone tablet in HR-FET cycle in Japanese patients. Methods: This study was multicenter, single arm, prospective study. Patients with infertility were administered 300 mg/day of vaginal progesterone tablet for luteal phase support in HR-FET cycle from 2015 to 2016. Results: Main outcomes were available for 344 patients, of which 49 in the cleavage stage ET group and 295 in the blastocyst ET group. Ongoing pregnancy rate were 10.2% in cleavage stage ET group and 28.1% in blastocyst ET group. As for the secondary outcomes in the blastocyst ET group, embryo quality of blastocyst, the number of past ET, and maternal age were significantly associated with pregnancy rate at 2 weeks after progesterone administration. Mean serum progesterone level was 12.1 ± 5.3 ng/mL at the day of ET. There was no relationship between the serum progesterone level on ET day and either of pregnancy rates at 2, 4, and 6 weeks after progesterone administration. Conclusions: The efficacy of monotherapy using 300 mg/day of vaginal progesterone tablet in HR-FET was shown and the serum progesterone level on ET day did not affect pregnancy rate. (UMIN000021983)
Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio in Poststroke Depression: A Systematic Review and Meta-Analysis
Authors: Sarejloo Shirin , Abadifard Erfan , Othman Zhian Jamal , Zafarani Fatemeh , Khanzadeh Monireh , Sadigh-Eteghad Saeed , Farajdokht Fereshteh , Mohammadpoorasl Asghar , Khanzadeh Shokoufeh 
Published: August 2022

Objectives. Evidence shows that stroke-induced inflammatory responses play an essential role in the development of poststroke depression (PSD). The goal of this systematic review and meta-analysis was to critically evaluate the literature regarding the use of the neutrophil to lymphocyte ratio (NLR) as a reliable means to detect early PSD development, to help clinicians institute early interventions and improve outcomes. Methods. Electronic databases, including Web of Science, PubMed, Google Scholar, and Scopus, were searched, and eight studies were included. We assessed the certainty of the associations with GRADE methods. Results. We found that patients with PSD had higher NLR than the stroke patients with no depression (

SMD
=
0.51

;

CI

95
%
=
0.29

-0.73,

p
<
0.001

). Also, we found a significantly higher PLR in the patients with PSD when compared to the stroke patients with no depression (

SMD
=
0.66

;

CI

95
%
=
0.19

-1.13,

p
<
0.001

). Conclusion. These findings indicated that NLR and PLR could be considered inexpensive biomarkers for the prediction of PSD.
A Comprehensive Nursing Model Combined with High-Quality Nursing Intervention for Antiviral Therapy in Patients with Chronic Hepatitis B
Authors: Yang Wei , Tian Xiaofeng , Liang Jing 
Published: August 2022

Objective. To investigate the effect of comprehensive nursing combined with high-quality nursing intervention on the compliance, anxiety, and mental state of patients with chronic hepatitis B undergoing antiviral therapy. Methods. A total of 100 patients with chronic hepatitis B admitted to China-Japan Union Hospital from December 2017 to August 2020 were recruited and assigned to receive either routine nursing (control group, n = 50) or comprehensive nursing plus high-quality nursing (observation group, n = 50) via the random number table method. The outcome measures included compliance, psychological state, and treatment effects. Results. Before the nursing, there was no significant difference in the compliance scores between the two groups of patients

P
>
0.05

. After the nursing, the observation group had higher compliance scores than the control group

P
<
0.001

. Before the intervention, the two groups had similar Self-Rating Anxiety Scale (SAS) scores

P
>
0.05

. After the intervention, patients in the observation group showed lower SAS scores and a lower incidence of negative emotions as compared to the control group

P
<
0.001

. The observation group showed a better outcome in terms of quality of life, Medical Coping Modes Questionnaire (MCMQ) scores, and the General Self-Efficacy Scale (GSES) scores when compared to those of the control group

P
<
0.001

. A higher treatment effective rate was witnessed in the observation group in contrast to the control group

P
<
0.001

. Conclusion. The comprehensive nursing model combined with high-quality nursing intervention improves the psychological state and compliance of patients with chronic hepatitis B, with favorable treatment efficiency, which shows good potential for clinical promotion.
Agencias infantiles en la escuela
Authors: Fatyass Rocio 
Published: August 2022

(analítico)Se abordan prácticas de agencia de niñas y niños de clases populares en una escuela primaria en Villa María, Córdoba, Argentina. Desde un método etnográfico, el problema de investigación se vincula con la agencia infantil en contextos escolares. El interrogante refiere a cuáles son las modalidades que asumen las prácticas de agencia infantil, según cómo niñas y niños resisten a los ordenamientos temporales y espaciales en la escuela, resignifican miradas y clasificaciones de las docentes y disputan por la distribución de recursos materiales. Los resultados señalan que niñas y niños producen diversos procesos de agencia desde discursos e interacciones intergeneracionales que se tejen en la cotidianidad escolar. Estas prácticas no son instrumentales ni en todos los casos reflexivas, más bien están socialmente incorporadas.
Palabras clave: Infancias; escuela; agencia; autoridad adulta; desigualdad.
Manager, coach and sports club participant perceptions of health promotion
Authors: Van Hoye Aurelie , Johnson Stacey , Lemonnier Fabienne , Crochet Laurianne , Maso Freddy , Lecoarer Tiphaine , Rostan Florence , Tezier Benjamin , Vuillemin Anne 
Published: August 2022

Objectives: Sports clubs’ investment in health promotion (HP) has so far been limited, and efforts to understand where gaps exist in implementation are few and far between. This mixed-method study analysed managers’, coaches’ and sports participants’ perceptions of HP in a single sports club. Design: A mixed-method cross sectional design was used. Setting: The goal was to assess HP perceptions at the macro (club), meso (managers) and micro (coaches) levels with respect to four key health determinants. Method: Quantitative data were collected from 237 participants using e-PROSCeSS questionnaires. Qualitative data collection included two meetings with managers and a focus group with sports club participants. Data analysis took place by means of a hybrid thematic analysis informed by the health promoting sports club (HPSC) model. Results: Similar answer patterns among managers, coaches and sports club participants illustrated that social and environmental determinants scored higher than organisational and economic determinants, which was consistent with qualitative findings. Only one significant difference was found between managers and sports club participants – for organisational determinants at the macro level. In others words, all club actors agreed that sports clubs needed to invest in HP policy and funding, and not only acknowledge that HP is an integral outcome of sports participation. Gender differences in HP perceptions were identified, while being a volunteer compared to a non-volunteer did not make any significant difference. Conclusion: Study findings raise questions about how best to implement and evaluate sports club HP, especially in relation to policies and resources. This is essential to understand the interactions between macro, meso and micro level health determinants and the temporal implications of implementing a HPSC’s approach.
Two important factors affecting the prognosis of patients treated with sorafenib followed by regorafenib for advanced hepatocellular carcinoma
Authors: Li Ning , Zheng Hongxia , Yu Qingtan , Chen Fei , Su Xiaoqing , Qiu Xuan 
Published: August 2022

Objective To investigate the effects of hand–foot syndrome (HFS) and fatigue on disease progression and survival in patients treated with sorafenib followed by regorafenib for advanced hepatocellular carcinoma. Methods A retrospective analysis of patients with advanced hepatocellular carcinoma treated with sorafenib in our hospital from 1 October 2018 to 31 October 2021 was performed, and clinical and pathological data and follow-up results were obtained. Patients were divided into groups according to the severity of HFS and fatigue. Survival analysis among the groups was performed using the Kaplan–Meier method, continuous variables were analyzed using the t-test, and factors associated with survival were evaluated using multivariate Cox regression analysis. Results The study included 150 men and 23 women with a mean age of 60.77 years (range: 40–85 years). The median overall survival (OS), progression-free survival (PFS), and time to tumor progression (TTP) increased with increasing severity of HFS. Conversely, the median OS, PFS, and TTP decreased with increasing severity of fatigue Conclusion HFS and fatigue were independent risk factors affecting TTP, PFS, and OS among patients treated with sorafenib followed by regorafenib for advanced hepatocellular carcinoma.
Exploring the perspectives of ‘young adults’ (18–24) who have been in formal care and their experiences of attending a socially prescribed community allotment gardening group
Authors: Moore Emma J , Thew Miranda 
Published: August 2022

Introduction: Young adults who have experienced periods of time being ‘in care’ are one of the most socially deprived populations within society, with their needs largely unmet and often not fully understood. Despite the significant attempts to invest in community-based ‘social prescribing’ interventions to address such health inequalities, there is a dearth of understanding regarding how such occupation-based community groups are experienced by this particular population. This UK based qualitative study aimed to explore the experiences of young adult ‘Care Leavers’ regarding their participation in a socially prescribed community gardening group. Method: Semi-structured online interviews were conducted with six young care leavers aged between 18 and 24 years who regularly participated in a community gardening group. Interviews were recorded transcribed verbatim and analysed Braun and Clarke’s Thematic Analysis process by two researchers to maximise validity. Findings: Four key themes emerged: ‘Social belonging and connection’, ‘A safe space’, ‘Sense of achievement from active engagement’ and ‘The facilitatory aspects of nature’. The findings suggested nature-based co-occupation within a local group, enhanced social capital, self-identity and wellbeing. Conclusion: This study supports the emerging scope of using community occupation-based interventions with young adult ‘Care Leavers’ and offers an insight into their particular needs.
A “Human Rights” of our own? Chinese and Turkish Encounters with a Western Concept
Authors: Üngör Çağdaş 
Published: August 2022

AbstractThis article aims to compare the Turkish and Chinese reception of the “human rights” term, which enjoyed wide currency across the globe after the end of the Cold War. During the 1990s, as the global human rights discourse was embraced by dissidents in Turkey and China, the state elites remained skeptical of this concept, which was often perceived as a tool of Western imperialism. Unlike nationalists, Muslim and Confucianist conservatives saw some merit in the term “human rights” and discussed ways to appropriate it in their local contexts. In China and Turkey, “human rights” was often instrumental in promoting collective identities during the 1990s. Although the term's original emphasis on the individual somewhat disappeared in these countries, its embrace by various groups demonstrates that “human rights” discourse resonates with non-Western audiences.
Polylactic acid/polycaprolactone bionanocomposites containing zinc oxide nanoparticles: Structure, characterization and cytotoxicity assay
Authors: Babaei Amir , Haji Abdolrasouli Mehdi , Rostami Amir 
Published: August 2022

In the present study, zinc oxide nanoparticles (ZnO-NPs) were synthesized by a hydrothermal method followed by the fabrication of polylactic acid/polycaprolactone blend (PLA/PCL, 80/20 wt/wt) at various loadings of ZnO-NPs (2, 4, and 6 wt%) via melt mixing. FTIR and XRD patterns confirmed that the ZnO-NPs were successfully synthesized. The ZnO-NPs with an average diameter of about 46–73 nm were observed by the FESEM analysis. The effect of ZnO-NPs on morphological, thermal, UV absorption, mechanical, photochemical degradation, rheological and cell viability properties of PLA/PCL blend were investigated. FESEM micrographs of bionanocomposites demonstrated that polycaprolactone was dispersed as a droplet to the Polylactic acid matrix phase. DSC analysis showed that the addition of ZnO-NPs increased the degree of crystallinity and melting temperature of the PLA. Mechanical assessment of the bionanocomposites reveals that the addition of 2, 4 and 6 wt.% of ZnO-NPs into the blend sample leads to increase in the tensile modulus by about 5.4, 11 and 24%. The MTT assay results implied that cell viability of the both filled and unfilled samples is greater than 90% indicating their biocompatibility to the fibroblast cells. It is observed that the melt linear viscoelastic properties of the prepared bionanocomposites are under control of LA/PCL chain degradation and hydrodynamic nanoparticles interaction.
Effect of evidence-based information management and practice training on librarians’ critical thinking: A randomized educational trial
Authors: Esmaeilzad Sima , Gavgani Vahideh Zarea , Zarei Atefeh , Familrouhany Seyed Ali Akbar 
Published: August 2022

Critical thinking is one of the most important elements in making the right decision in every profession. Evidence based practice shows potential to empower the critical thinking skills of practitioners. The aim of this study was to determine the effect of evidence-based information management and practice (EBIMP) training course on the promotion of medical librarians’ critical thinking. This study is a randomized double-blind educational trial in the form of a parallel trial. A sample of 60 librarians were recruited nationwide in the study through the volunteer enrollment to the evidence-based information management and practice training course. Intervention group received a 10-module virtual course focusing on evidence-based information management. But the control group received a basic course of evidence-based medicine. The courses were delivered through virtual learning system and data was collected through California Standard Critical Thinking Skills Questionnaire Form B (CCTST). Data were analyzed with Covariance Analysis (ANCOVA), Chi-square (χ²), Kolmogorov-Smirnov and Levin tests, and t-test, using SPSS 25. The findings showed that the critical thinking skills of participants after training of the information management and evidence-based practice (EBIMP) had significant improvement in the intervention group compared with the control group regarding the “inference” (4.86 ± 1.94 vs 4.20 ± 1.32), “assessment” (7.90 ± 1.77 vs 5.90 ± 1.70), “Inductive reasoning” (8.67 ± 2.32 vs 6.37 ± 1.87), “deductive reasoning” (6.47 ± 2.04 vs 5.77 ± 1.97) subskills. Education of evidence-based information practice could be effective in promotion of critical thinking skills of medical librarians. This study suggests evidence-based information practice to be added to the curriculum of medical library and information science fields. Trial registration: This study was registered with number 9000.1v1 in Registry of Efficacy and Effectiveness Studies (REES).
Contribution of an anticancer drug compounding robot in reducing the risks of manual preparation in a hospital pharmacy unit specialized in oncology
Authors: Cherif Chefchaouni Ali , Boudina Yassine , Chennaq Meryem , Belahcen Mohammed Jaouad , Rahali Younes 
Published: August 2022

Introduction In the last few years, pharmaceutical technology has evolved. In the field of oncology pharmacy, robots for the preparation of anti-cancer drugs have appeared to progressively replace manual preparation. The objective of this study is to evaluate the contribution of the robot in reducing the risk of manual preparation. Methods The study was conducted at the pharmacy of the National Institute of Oncology in Rabat (May–August 2021). The method used to compare the two types of preparation is the method of analysis of failure modes, their effects and their criticality (FMECA). It will calculate the criticality index (CI = severity × frequency × detectability). The risks have been categorized into human, technical, and environmental risks. Results The anticancer drugs reconstitution step was the most critical in manual preparation (CI = 126.7) and robotic preparation (CI = 40.7). The robot has made it possible to reduce several CIs of manual preparation including: musculoskeletal disorders of pharmacy operators −93 (89%), error in cancer drug and diluent selection −72 (60%), as well as lack of traceability −145 (97%). Conclusion The preparation robot has made it possible to reduce many of the risks of manual preparation, and constitutes an important advance in the field of oncology pharmacy.
KRAS-targeted therapy in the treatment of non-small cell lung cancer
Authors: Yun Jina , Nakagawa Reid , Tham Kenneth 
Published: August 2022

Objective KRAS mutations are one of the most common driver mutations in non-small cell lung cancer. Though previously believed to be an undruggable target, recent advances in therapeutics have seen new targeted agents against KRAS mutations. The objective of this article is to review currently available and upcoming KRAS-targeted treatments. Data sources Currently available trials examining KRAS-targeted therapy in non-small cell lung cancer were examined by searching for the keyword “ KRAS inhibitors.” The pivotal trials for sotorasib and adagrasib were reviewed for this article. Data summary Mutated KRAS can be challenging to target for a variety of reasons. In 2021, the US Food and Drug Administration approved sotorasib for the treatment of adult patients with locally advanced or metastatic non-small cell lung cancer with KRAS G12C mutation as determined by a Food and Drug Administration-approved test, who have received at least one prior systemic therapy. A multicenter, single-group, open-label, phase 2 trial was able to demonstrate that sotorasib was able to demonstrate objective response, progression-free survival, and overall survival in this patient population. A phase 3 trial comparing sotorasib to docetaxel in the subsequent-line treatment of KRAS G12C non-small cell lung cancer is currently ongoing. There are other KRAS-targeted agents currently under study, including adagrasib, with growing interest in targeting KRAS downstream pathways. Conclusion Further trials need to be conducted in order to identify other targeted agents for KRAS and the appropriate place in therapy among currently approved treatments for non-small cell lung cancer.