bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of preoperative risk factors for early recurrence after curative pancreatoduodenectomy for resectable pancreatic adenocarcinoma
Authors: Burasakarn Pipit , Thienhiran Anuparp , Fuengfoo Pusit , Hongjinda Sermsak 
Published: June 2022

Abstract

Objectives
To investigate the risk factors for early recurrence after curative pancreatoduodenectomy for resectable pancreatic ductal adenocarcinoma.

Methods
All data were retrospectively collected from patients with resectable pancreatic ductal adenocarcinoma who had undergone pancreatoduodenectomy at the Department of Surgery, Phramongkutklao Hospital, from January 2015 to December 2020. The preoperative and perioperative risk factors were included into the analysis.

Results
In total, 34 patients were included in the study. The median time for recurrence and median survival time were 17 and 20 months, respectively. The 1, 3, and 5 year disease-free survival rates were 59.6%, 23.87%, and 23.87%, respectively, while the 1, 3, and 5 year overall survival rates were 81%, 24.7%, and 12.4%, respectively. Seventeen patients (50%) from a total of 34 patients had recurrence, and ten patients (29.41%) had recurrence within 12 months. The independent preoperative risk factor associated with adverse disease-free survival was tumor size > 4 cm (hazard ratio [HR], 14.34, p=0.022). The perioperative risk factors associated with adverse disease-free survival were pathological lymphovascular invasion (HR, 4.31; p=0.048) and non-hepatopancreatobiliary surgeon (HR, 5.9; p=0.022). Risk factors associated with poor overall survival were microscopical margin positive (R1) resection (HR, 3.68; p=0.019) and non-hepatopancreatobiliary surgeon (HR, 3.45; p=0.031).

Conclusions
Tumor size > 4 cm from the preoperative imaging study was a poor prognostic factor for early recurrence after curative pancreatoduodenectomy for resectable pancreatic adenocarcinoma indicated that they may have radiological occult metastasis, thus, staging laparoscopy may reduce the number of unnecessary laparotomies and avoid missing radiologically negative metastases.
Energy and Entropy in Open and Irreversible Chemical Reaction–Diffusion Systems with Asymptotic Stability
Authors: Ledesma-Durán Aldo , Santamaría-Holek Iván 
Published: June 2022

Abstract
This work proposes a novel approach for the study of open systems described by completely irreversible reaction mechanisms in non-homogeneous systems and subject to non-equilibrium boundary conditions. Using the non-equilibrium thermodynamics framework, we consider that in an autonomous system of reaction–diffusion equations, the thermodynamic potentials can be constructed from a Lyapunov function that depends directly on the eigenvalues and eigenvectors of the linearized problem. By interpreting this Lyapunov function as the free energy and redefining the chemical potentials, we were able to demonstrate the local stability properties of non-equilibrium stationary states, i. e., states that do not change with time due to a complex equilibration of internal and external flows. We demonstrate the consistency of our hypotheses with basic thermodynamic principles such as the spectral decomposition of entropy production and the Glansdorff–Prigogine evolution criterion. We discuss how our approach allows us to understand thermodynamic systems without assuming equilibrium or any kind of reversibility.
The Contributions of Public Libraries to Satisfy Intellectual Curiosity of Rural Inhabitants in West Bengal: An Indian Case Study
Authors: Munshi Shamim Aktar , Ansari Mehtab Alam , Barsha Sayantoni 
Published: June 2022

Abstract
The purpose of this study is to investigate the contributions of public libraries to the satisfaction of the intellectual needs of rural inhabitants in West Bengal, India. The study applied a quantitative survey method with the help of a well-structured questionnaire. Questionnaires were distributed among to the users (students, officers/professionals, self-employed individuals, businessmen, jobseekers, retired persons, and housewives) of 45 rural public libraries in five selected districts of West Bengal. The study found that the largest group of respondents belonged to the students and jobseekers categories, who visit the rural public libraries for seeking academic and job-related information. Many students from humble backgrounds were solely dependent on public libraries because they have procured some textbooks from middle school up to graduation level. Jobseekers were mostly consulting the Career Guidance Section of the library to prepare for various competitive exams. The study also revealed that public libraries have been trying to satisfy the intellectual and informational needs of the rural inhabitants by providing various services and facilities. Respondents have further reported that public libraries should adopt modern technologies and provide ICT-based library services as well. The outcome of this study would help to develop and upgrade the public library collection, services, and facilities in developing countries in a way that reflects patrons’ stated needs.
The University Library’s Strategic Process: Competing Through Plans, Positions, and Resources
Authors: Edgar William B. 
Published: June 2022

Abstract
The traditional notion of university library strategy has been that of a pattern of goal-oriented activities that implement a strategic plan. Through conceptual analysis, this paper integrates strategic planning with two other perspectives—strategy based upon competitive position and upon library resources—to propose that a university library can best serve its academic community through a “strategic process” when supporting research and teaching. Drawing extensively upon applicable library science and strategic management literature, the paper presents the potential contribution of each perspective and of the entire strategic process using relevant examples. Successfully applying the strategic process enables university library managers to move forward with optimism in difficult competitive and financial situations. The process enables the university library to gain sustainable competitive advantage over its competitors by providing faculty and students with intellectual value in support of their discovery and education. As it operates, the strategic process empowers the university library to fulfill its traditional mission—providing persistent, generalized access to information—but to do so in transformed ways. The process also enhances library managers’ ability to communicate such successes to university decision-makers, illuminating the library’s effective use of scarce financial resources.
Prolonged APTT and autoimmune overt hypothyroidism identified postpartum: a case report
Authors: Hjelm Lundgaard Maja , Carlé Allan , Birgitte Christiansen Ulla , Sørensen Anne , Risom Kristensen Søren , Andersen Stine Linding 
Published: June 2022

Introduction
Thyroid disorders have been linked to abnormalities in the coagulation system, and a hypocoagulant state has been proposed in hypothyroidism. The assessment of thyroid function is, however, not routinely recommended as part of the assessment for coagulation disorders.

Case presentation
We present a 32-year-old woman who had no history of thyroid disease and who recently gave birth preterm because of severe preeclampsia and intrauterine growth restriction. Due to severe placental dysfunction, she underwent a routine biochemical assessment of the coagulation system 6 months postpartum, and a prolonged activated partial thromboplastin time (APTT) (43 s) was identified along with a low level of coagulation factor VIII (0.44 IU/mL), and a low level of von Willebrand factor (vWF) antigen (0.35 IU/mL), vWF activity (0.38 IU/mL) as well as reduced generation of thrombin. The assessment of thyroid function in the patient identified autoimmune, overt hypothyroidism with a thyroid-stimulating hormone (TSH) concentration of 139 mIU/L, low levels of the peripheral thyroid hormones (total thyroxine: 43 nmol/L, total triiodothyronine: 0.9 nmol/L), and high levels of thyroid peroxidase antibodies (296 U/mL) as well as thyroglobulin antibodies (927 U/mL).

Conclusion
In this case, prolonged APTT provided a diagnostic clue for the assessment of thyroid function in a young woman with a recent history of severe placental dysfunction. The identification of autoimmune, overt hypothyroidism emphasizes that measurement of TSH may be of clinical importance in cases of unexplained prolonged APTT or other biochemical signs of abnormalities in the coagulation system.

Established facts

Hypothyroidism has been associated with alterations of the coagulation system suggesting a hypocoagulant state.

At present, measurement of thyroid-stimulating hormone is not routinely recommended as part of the assessment for coagulation disorders.

Novel insights

In this case, biochemical assessment of the coagulation system was routinely performed following a pregnancy complicated by severe placental dysfunction.

Overt hypothyroidism of autoimmune origin was identified secondary to prolonged activated partial thromboplastin time (APTT) postpartum along with low levels of coagulation factor VIII, von Willebrand factor, and thrombin generation.

Measurement of thyroid-stimulating hormone may be considered in cases of unexplained prolonged APTT.
Parental Depression Screening in Pediatric Health Care Settings: A Scoping Review
Authors: Hunt Ava Marie , Uthirasamy Nila , Porter Sallie , Jimenez Manuel E. 
Published: June 2022

BACKGROUND AND OBJECTIVES
Parental depression affects as many as 1 in 5 US families. Pediatric professionals can play an important role in detecting parental depression, yet most studies on parental depression screening focus only on the postpartum period. The authors performed this scoping review to understand the existing literature on parental depression screening outside the postpartum period (child &gt;12 months old) and to identify knowledge gaps.

METHODS
Sources for this research include PubMed, CINAHL, SCOPUS, Web of Science, and APA Psych Info. We included English language papers concerning screening for maternal and/or paternal depression or mood disorders outside of the postpartum period by pediatric clinicians or in a pediatric health care setting. Extracted variables included publication year, title, author(s), country, geographic setting, clinical setting, child age range (in years), parental focus, sample size, study type, approach, screening instrument(s), and findings.

RESULTS
Forty-one papers were included. The proportion of positive parental depression screens was consistently high across the included studies. Relatively few structured screening programs outside of the postpartum period were identified, especially for fathers. The included studies suggest that screening can be accomplished in pediatric settings, but appropriate referral and follow-up of positive screens poses a major challenge. This review was limited to English language papers concerning parental depression outside of the postpartum period.

CONCLUSIONS
These findings suggest that screening for parental depressive symptoms outside the postpartum period could identify families in need of support. Research is required to identify best practices for referral and follow-up of parents who screen positive.
Decreasing Misdiagnoses of Urinary Tract Infections in a Pediatric Emergency Department
Authors: Ostrow Olivia , Prodanuk Michael , Foong Yen , Singh Valene , Morrissey Laura , Harvey Greg , Campigotto Aaron , Science Michelle 
Published: June 2022

BACKGROUND AND OBJECTIVES
Urinary tract infection (UTI) is a common diagnosis in the emergency department (ED), often resulting in empirical antibiotic treatment before culture results. Diagnosis of a UTI, particularly in children, can be challenging and misdiagnosis is common. The aim of this initiative was to decrease the misdiagnosis of uncomplicated pediatric UTIs by 50% while improving antimicrobial stewardship in the ED over 4 years.

METHODS
By using the Model for Improvement, 3 interventions were developed: (1) an electronic UTI diagnostic algorithm, (2) a callback system, and (3) a standardized discharge antibiotic prescription. Outcome measures included the percentage of patients with UTI misdiagnosis (prescribed antibiotics, but urine culture results negative) and antibiotic days saved. As a balancing measure, positive urine culture results without a UTI diagnosis were reviewed for ED return visits or hospitalization. Statistical process control and run charts were used for analysis.

RESULTS
From 2017 to 2021, the mean UTI misdiagnosis decreased from 54.6% to 26.4%. The adherence to the standardized antibiotic duration improved from 45.1% to 84.6%. With the callback system, 2128 antibiotic days were saved with a median of 89% of patients with negative culture results contacted to discontinue antibiotics. Of 186 patients with positive urine culture results with an unremarkable urinalysis, 14 returned to the ED, and 2 were hospitalized for multiresistant organism UTI treatment.

CONCLUSIONS
A UTI diagnostic algorithm coupled with a callback system safely reduced UTI misdiagnoses and antibiotic usage. Embedding these interventions electronically as a decision support tool, targeted audit and feedback, reminders, and education all supported long-term sustainability.
СИНТЕЗ ЦЕОЛІТУ З ПРИРОДНОЇ ГЛИНИ І ЗОЛИ РИСОВОГО ЛУШПИННЯ В ЯКОСТІ ПЕРСПЕКТИВНОГО ФОТОКАТАЛІЗАТОРА ДЛЯ ЗМЕНШЕННЯ ЗАБОРОНЕНОЇ ЗОНИ ДІОКСИДУ ТИТАНУ
Authors: Сюкрі Сюкрі , Факрі Ахмад , Сафні Сафні , Норта Тетра Оллі 
Published: June 2022

In this study, we have utilized clay from Pariaman, Indonesia enriched with silica from rice husk ash to produce zeolite through a hydrothermal process. The resulting zeolite is then composited with the most common semiconductor photocatalyst, an anatase titanium oxide, to increase the semiconductor efficiency in terms of particle distribution and light sources activation. From X-Ray Fluorescence (XRF) measurement, it can be seen that the Si/Al mole ratio in the clay has been successfully increased from 1.8 to 2.0. These data are strengthened by the results of X-Ray Diffraction (XRD) analysis which shows the formation of zeolites of several types consisting of zeolite faujasite, P1, sodalite, X, and nu-6. When the synthesized zeolite is mixed with titania anatase, a composite is formed as evidenced by FTIR analysis with the appearance of Si-O-Si and Si-O-Al absorption bands for zeolite and Ti-O-Ti from titania. This zeolite has been shown to reduce the bandgap energy of titanium oxide after the two materials have been composited. Measurements with Ultraviolet-Visible Diffuse Reflectance Spectroscopy (UV-Vis DRS) showed that the TiO2-anatase band gap decreased by about 20 %, from 3.20 to 2.56 eV allowing theoretically the composite to be considered as a promising photocatalyst.
ОБҐРУНТУВАННЯ ВИБОРУ МОЛОЧНОЇ СИРОВИНИ ДЛЯ ОДЕРЖАННЯ ДОБАВОК ДІЄТИЧНИХ СЕЛЕН-БІЛКОВИХ ЗА ПОКАЗНИКАМИ ЇЇ СТРУКТУРИ
Authors: Применко Владислав Г. , Сефіханова Катерина A. , Геліх Анна O. , П. Головко Микола , Василенко Ольга О. 
Published: June 2022

Мета. Обґрунтувати вибір сировини для селен-білкових дієтичних добавок, а саме виду сироватки в якості матриці для їх виробництва, і визначити подальшу можливість використання добавок в технології кулінарних виробів спеціального призначення. Методи. Визначення структурних характеристик зразків молочної сироватки проводили за допомогою електронного мікроскопа Quattro ESEM при збільшенні в 10000 і 1000 разів. Аналіз кількісних і розмірних характеристик досліджуваних частинок проводився з використанням програми MS Excel. Одержані результати. Обґрунтовано спосіб і режим згущення сироватки, проведено аналіз однорідності зразків сироватки безлактозної і з її вмістом при різних режимах згущення. Визначено співвідношення складових селен-білкових добавок і характер взаємодії їх компонентів. Висновки. Аналіз структури модельних систем з використанням низьколактозної молочної сироватки і солей селену, конденсованих контактним способом, дозволив встановити раціональний вміст останніх в діапазоні 0.0087...0.0176 %, при якому спостерігається утворення однорідної дрібнодисперсної мікроструктури. Це дозволяє передбачати високі технологічні властивості, стабільність стуктури готових селен-білкових добавок при їх зберіганні і застосуванні.
ІЗОТЕРМІЧНИЙ ПЕРЕРІЗ ДІАГРАМИ СТАНУ СИСТЕМИ ZrO2–HfO2–Sm2O3 ПРИ 1600 C
Authors: В. Юрченко Юрій , Корнієнко Оксана А. , І. Биков Олександр , Самелюк Анатолій В. 
Published: June 2022

За результатами зразків досліджених методом рентгенофазового та мікроструктурного аналізів досліджено фазові рівноваги в потрійній системі ZrO2–HfO2–Sm2O3. Утворення нових фаз у системі ZrО2–HfO2–Sm2O3 при 1600 °С не спостерігалося. Встановлено, що в дослідженій системі при 1600 °С утворюються поля твердих розчинів на основі тетрагональної (Т) модифікації ZrО2, моноклинної (М) модифікацій HfO2 і моноклинної (В) модифікацій Sm2O3, а також упорядкованої фази зі структурою типу пірохлору (Ру) Ln2Zr2O7 (Ln2Hf2O7). Визначено границі фазових полів та параметри елементарних комірок утворених фаз. Досліджений ізотермічний переріз системи ZrО2–HfO2–Sm2O3 характеризується утворення неперервних рядів кубічних твердих розчинів на основі фази зі структурою типу пірохлору Sm2Zr2O7 (Sm2Hf2O7) та зі структурою типу флюориту F-ZrO2 (HfO2). Встановлено, що в дослідженій системі утворюється дві області гомогенності кубічних твердих розчинів зі структурою типу флюориту. Існування цих областей гомогенності обумовлено розривом розчинності фази F-ZrO2 (HfO2) в області існування упорядкованої фази зі структурою типу пірохлору Sm2Zr2O7 (Sm2Hf2O7). Встановлено, що твердий розчин на основі кубічної модифікації зі структурою типу флюориту існує в рівновазі з усіма фазами, що спостерігаються в системі. Ізотермічний переріз дослідженої діаграми стану системи ZrO2–HfO2–Sm2O3 при 1600 °С характеризується наявністю однієї трифазної (F+T+M), а також п’яти двофазних (B+F, дві – F+Py, M+F, T+F) областей.
КВАНТОВО-ХІМІЧНЕ МОДЕЛЮВАННЯ АЦИДОХЛОРОКОМПЛЕКСІВ Cu2+, ЩО МІСТЯТЬ АНІОНИ ОРГАНІЧНИХ КИСЛОТ
Authors: Варгалюк Віктор Ф. , Полонський Володимир А. , Курасова Юлія Д. 
Published: June 2022

Розглядаються результати квантово-хімічного моделювання (Gaussian 09, функціонал B3LYP) комплексних структур, які можуть утворюватися з аквакомплексів Cu2+, хлорид-іонів та аніонів органічних кислот (малонова, бурштинова, малеїнова, фумарова, мурашина, оцтова, пропіонова, бутанова, акрилова). Показано, що досліджуваний ряд органічних кислот утворює дві лінійні кореляційні залежності pК монозаміщених ацидоаквакомплексів Cu2+ від ефективного заряду центрального атома. Одна відноситься до аніонів одноосновних кислот, інша – до аніонів двоосновних кислот. Використання параметрів відповідної pК, z*(Cu2+)-залежності та результатів розрахунку z*(Cu2+) дозволило визначити значення pК для акрилатних комплексів Cu2+, що дорівнює 1.778, відомості про яку у літературі відсутні. За ступенем зміни ефективного заряду іонів Cu2+ у комплексах [Cu2+(L)] оцінено електронодонорність лігандів: аніони органічних кислот (−51.95 %) > Cl− (−47.75 %) > H2O (−21.45 %). Однак, у полілігандних аквакомплексах, за рахунок утворення гідрату L · H2O, аніони органічних кислот поступаються хлорид-іонам. При введенні аніонів хлору у внутрішню координаційну сферу монозаміщених аніонами органічних кислот аквакомплексу Cu2+ спостерігається закономірне послаблення зв'язків Cu2+–L. Ступінь зменшення Eb(Cu2+-L) залежить від природи органічної кислоти. Для насичених структур ΔEb знаходиться в інтервалі 2–8 кДж/моль, для ненасичених досягає 20 кДж/моль. Синхронно змінюється і енергетика реакції заміщення молекул води в ацидоаквакомплексі Cu2+ аніонами хлору (з −4 до −30 кДж/моль). Це, а так само те, що енергетичний ефект реакції приєднання Cl− до ацидоаквакомплексів Cu2+ з ненасиченими аніонами є ще більшим, досягаючи −62 кДж/моль у присутності фумарат-іонів, створює сприятливі початкові умови для синтезу змішаних ацидохлорокомплексів Cu2+, які містять аніони ненасиченних кислот. У розчинах насичених кислот очікується утворення тільки комплексів виду [Cu2+(H2O)4(Cl)] та [Cu2+(H2O)4(L)].
New Insights into Debussy's Sketches for the String Quartet Op. 10
Authors: Delécluse François 
Published: June 2022

Abstract
This article provides new perspectives on Claude Debussy's compositional process in his String Quartet through a fresh examination of existing sources, particularly a sketchbook kept in the Bibliothèque nationale de France. First, the fragmentary nature of the material contained in the sketchbook implies the existence of another manuscript, now lost. By analyzing Debussy's notations for his String Quartet in greater detail, it is possible to question the different functions the latter took on in the compositional process: in addition to the musical ideas simply noted as an aide-memoire, there are more exploratory musical fragments. Furthermore, the description and analysis of the sources of the String Quartet's creative process enhance our knowledge of Debussy's compositional methods and techniques. These new insights into the sources also show how Debussy adapted to certain social and aesthetic constraints when writing the String Quartet. The compositional context, the very genre of the quartet, and the fact that Debussy was close to Chausson and the Société nationale, led him to seek compositional solutions to combine the techniques of the Franck school with the personal aesthetic he was developing at the time. In particular, the article reconstructs part of the composer's reflection on the cyclic design, which is at the heart of the questions raised in the sketches.
Adoption and Transformation of Traditional Forms in the Fourth String Quartet of Béla Bartók
Authors: Borio Gianmario 
Published: June 2022

Abstract
In describing the form of his Fourth String Quartet, Bartók employed the terminology of the German Formenlehre with which he was acquainted thanks to the teaching of Hans Koessler. Bartók's elucidation suggests that the models for the construction of thematic units, contrasts, developments and closing segments, which were normative for the sonata cycle in the nineteenth century, continued to exercise their influence despite the distance from functional tonality. An analysis of the five movements of the Fourth String Quartet with systematic reference to Bartók's synopsis shows that a subtle dialectic between adoption and transformation was at stake. The principles of traditional form gained new strength through the reinvention of harmonic structures, melodic lines and hypermetric groups. The symmetrical–architectural framework was preserved but filled with unconventional tone progressions, irregular phraseology, and a new sense for development and reprise.