bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does indocyanine green fluorescence angiography impact the intraoperative choice of procedure in free vascularized medial femoral condyle grafting for scaphoid nonunions?
Authors: Mulica Markus , Horch Raymund E. , Arkudas Andreas , Cai Aijia , Müller-Seubert Wibke , Hauck Theresa , Ludolph Ingo 
Published: September 2022

BackgroundFree vascularized medial femoral condyle (MFC) bone grafts can lead to increased vascularity of the proximal pole and restore scaphoid architecture in scaphoid nonunions. The intraoperative perfusion assessment of the bone graft is challenging because the conventional clinical examination is difficult. Indocyanine green (ICG) angiography has previously been shown to provide a real-time intraoperative evaluation of soft tissue perfusion in reconstructive surgery. The present study investigated the utility of ICG angiography in patients treated with a free medial femoral condyle graft for scaphoid nonunions.MethodsWe performed a retrospective analysis of patients with scaphoid nonunions, in which ICG angiography was used intraoperatively for perfusion assessment. The medical records, radiographs, intraoperative imaging, and operative reports of all patients were reviewed. Intraoperative ICG dye was administered intravenously, and laser angiography was performed to assess bone perfusion. The scaphoid union was examined using postoperative CT scans.ResultsTwo patients had documented osteonecrosis of the proximal pole at the time of surgery. Four patients received a nonvascularized prior bone graft procedure, and a prior spongiosa graft procedure was performed in one patient. The mean time from injury to the MFC bone graft surgery was 52.7 months, and the mean time from prior failed surgery was 10.4 months. Perfusion of the vascular pedicle of the MFC and the periosteum could be detected in all patients. In two patients, even perfusion of the cancellous bone could be demonstrated by ICG angiography. Following transplantation of the bone graft, patency of the vascular anastomosis and perfusion of the periost were confirmed by ICG angiography in the assessed cases. No additional surgery regarding a salvage procedure for a scaphoid nonunion advanced collapse was necessary for the further course.ConclusionICG-angiography has shown to be a promising tool in the treatment of scaphoid nonunion with medial femoral condyle bone grafts. It enables intraoperative decision making by assessment of the microvascular blood supply of the periosteum and the vascular pedicle of the MFC bone graft. Further studies need to evaluate the impact on union rates in a long-term follow-up.
Hybrid surgery versus endovascular intervention for patients with chronic internal carotid artery occlusion: A single-center retrospective study
Authors: Sun Tao , He Yiming , Wang Fei , Mao Bo , Han Mengtao , Zhao Peng , Wu Wei , Wang Yunyan , Li Xingang , Wang Donghai 
Published: September 2022

ObjectiveChronic internal carotid artery occlusion (CICAO) can cause transient ischemic attack (TIA) and ischemic stroke. Carotid artery stenting (CAS) with embolic protection devices and hybrid surgery combining carotid endarterectomy and endovascular treatment are effective methods for carotid revascularization. The objective of this study was to evaluate and compare the effect and safety of the two surgical procedures.MethodsThis was a single-center retrospective study. In this study, 44 patients who underwent hybrid surgery and 35 who underwent endovascular intervention (EI) at our center were enrolled consecutively between May 2016 and March 2022. All patients were classified into four groups (A-D), as described by Hasan et al. We recorded and analyzed clinical data, angiographic characteristics, technical success rate, perioperative complications, and follow-up data.ResultsThere was no significant difference in baseline characteristics between hybrid surgery group and EI group, except for plasma high density lipoproteins (HDL) levels (median [interquartile range]: hybrid surgery, 0.99 [0.88–1.18] vs. EI, 0.85 [0.78–0.98] mmol/L, P = 0.001). The technical success rate of hybrid surgery was higher than that of EI (37/44 [84.1%] vs. 18/35 [51.4%], P = 0.002; type A: 15/16 [93.8%] vs. 10/11 [90.9%], P = 1.000; type B: 9/10 [90.0%] vs. 5/7 [71.4%], P = 0.537; type C: 12/15 [80.0%] vs. 3/12 [25.0%], P = 0.004; type D: 1/3 [33.3%] vs. 0/5 [0%], P = 0.375). No significant difference was observed in the incidence of perioperative complications between the two procedures (hybrid surgery: 7/44 [15.9%] vs. EI: 6/35 [17.1%], P = 0.883). In addition, there were no significant differences in the rates of stroke and restenosis during follow-up.ConclusionsFor patients with symptomatic CICAO, hybrid surgery may have an advantage over EI in successfully recanalizing occluded segments. There was no significant difference in safety and restenosis between hybrid surgery and EI.
Evaluation of immune responses to Brucella vaccines in mouse models: A systematic review
Authors: Darbandi Atieh , Alamdary Shabnam Zeighamy , Koupaei Maryam , Ghanavati Roya , Heidary Mohsen , Talebi Malihe 
Published: September 2022

IntroductionDespite the accessibility of several live attenuated vaccines for animals, currently, there is no licensed vaccine for brucellosis in human populations. Available and confirmed animal vaccines may be harmful and considered inappropriate for humans. Thus, human vaccines for brucellosis are required. We aimed to evaluate the effects of Brucella vaccines on mouse models and discuss the potential mechanisms of these vaccines for the design of the appropriate human vaccines.Materials and methodsA systematic search was carried out in Web of Science, Embase, and PubMed/Medline databases. The following MeSH terms were applied: brucellosis, vaccine, Brucella, and vaccination. The original manuscripts describing the Brucella vaccines on mouse models were included. The review articles, editorials, correspondences, case reports, case series, duplicate publications, and articles with insufficient data were excluded.ResultsOf the 163 full texts that were screened, 17 articles reached to inclusion criteria. Combining the results of these trials revealed a reduction in bacterial load and colonization rate of Brucella in the spleen, an increase in inflammatory markers, especially IFN-γ and IL-4, and the highest levels of antibody classes in vaccinated animals compared to animals challenged with various virulent strains of Brucella. The majority of studies found that different anti-Brucella vaccines induced a significant protective effect in animals challenged with Brucella strains. Additionally, mice were given the highest level of Brucella vaccine protection and significant clearance of Brucella strains when the immunization was delivered via the IP (intraperitoneal) or IP-IN (intranasal) routes.ConclusionBrucella is responsible for half-million new cases globally annually, and the lack of a proper human vaccine poses the risk of brucellosis. A variety of vaccines are used to prevent brucellosis. Subunit vaccines and recombinant human vaccines have higher safety and protective properties. Although vaccination helps brucellosis control, it does not eradicate the disease. Thus, we recommend the following strategies. (a) establishment of a registration system; (b) close monitoring of slaughterhouses, markets, and herds; (c) training veterinarians; (d) legal protection of the consequences of non-compliance with preventive measures.
Risk Perception Related to COVID-19 and Future Affective Responses Among Healthcare Workers in Switzerland: A Mixed-Methods Longitudinal Study
Authors: Grazioli Véronique S. , Tzartzas Konstantinos , Blaser Jérémie , Graells Madison , Schmutz Elodie , Petitgenet Isabelle , Favrat Bernard , Zozaya Javier Sanchis , Kokkinakis Ioannis , Marion-Veyron Regis , Bodenmann Patrick 
Published: September 2022

Objectives: Whereas early findings suggest that risk perceptions related to COVID-19 affect psychological well-being in healthcare workers (HCWs), the temporal associations between these variables need to be clarified and HCWs lived experience further explored. This study proposes a mixed evaluation of COVID-19-related risk perception and affective responses among HCWs.Methods: A longitudinal mixed-method study was conducted. HCWs (N = 138) completed measures of COVID-19 risk perceptions, depression, anxiety, burnout and secondary traumatic stress (STS) at baseline and 6 months later. A subsample (n = 20) participated in semi-structured interviews exploring both risk perceptions and affective responses.Results: Main quantitative findings showed positive associations between worry to contaminate others and depression (IRR = 1.04, p &lt; 0.05), anxiety (IRR = 1.03, p &lt; 0.01), STS (b = 0.3, p &lt; 0.05), and perceptions of lacking protection (IRR = 1.04, p &lt; 0.05) with anxiety scores. Four themes emerged from the thematic content analysis: 1) life was turned upside down; 2) skills were put in quarantine; 3) dealing with patient discomfort; 4) balance to be found between protection and restrictions.Conclusion: These findings emphasize the importance to develop tailored interventions, such as group discussion sessions, to optimize risk perception and help manage uncertainty.
Penerapan Metode SARIMA dalam Model Intervensi Fungsi Step untuk Memprediksi Jumlah Pegunjung Objek Wisata Londa (Application of the SARIMA Method in the Step Function Intervention to Predict the Number of Visitors at Londa Tourism Object)
Authors: Christie Geovani , Hatidja Djoni , Tumilaar Rinancy 
Published: September 2022

Tujuan dari penelitian ini yaitu menentukan model intervensi pada data jumlah pengunjung di objek wisata Londa dan memprediksi jumlah pengunjung objek wisata Londa pada bulan Desember 2021 sampai Juni 2022 menggunakan model Seasonal Autoregresive Integrated Moving Average (SARIMA). Data yang digunakan adalah data jumlah pengunjung bulanan pada periode bulan Januari 2018 sampai bulan November 2021, yang diperoleh dari pihak pengelolah objek wisata Londa. Pola data jumlah pengunjung pada objek wisata Londa mengalami fluktuasi yang signifikan, yaitu pada bulan April 2020 (T=28). Model intervensi yang digunakan dalam penelitian ini yaitu fungsi step karena pengaruh yang terjadi berlangsung dalam kurun waktu cukup lama yaitu pada bulan April 2020 sampai November 2021 (T=28 sampai T=47). Model terbaik yang diperoleh dari hasil analisis data yaitu SARIMA (1,1,0)(1,1,0)[6] dengan orde intervensi b=0, s=5, dan r=2, dengan nilai MAPE dan MAE masing-masing sebesar 4,38% dan 0,397. Hasil prediksi dari bulan Desember 2021 sampai Juni 2022 secara berturut-turut yaitu 2550, 756, 347, 515, 1585, 1287 dan 2247 orang. Jumlah pengunjung akan meningkat pada waktu musim liburan yaitu Bulan Desember dan Juni.Kata kunci: Model intervensi; fungsi step; objek wisata Londa,ABSTRACTThe object of this study are to determine the intervention model of the number of visitors at the Londa tourism object and predict the number of visitors at the Londa tourism object for December 2021 to June 2020 using Seasonal Autoregresive Integrated Moving Average (SARIMA) models. The data used is monthly data for the period from January 2018 to November 2021, which was obtained from the manager of the Londa tourist object. The data pattem on the number of visitors at the Londa tourism object experienced significant fluctuations on April 2020 (T=28). The suspected intervention model is a step function because the effect of the intervention that occurred took place over a long period of time, from April 2020 to November 2021 (T=28 to T=47). The best model obtained from the results of data analysis is SARIMA (1,1,0)(1,1,0)[6] with an intervention order of b=0, s=5, and r=2, with MAPE and MAE values are 4,38% and 0,397. Forecasting results from December 2021 to June 2022 respectively, are 2550, 756, 347, 515, 1585, 1287 and 2247 people. The number of visitors will increase during the holiday season, i.e. December and June.Keywords: Intervention model; Londa tourism object; step function
Reverse sorting of immortalized megakaryocyte progenitor cell lines (imMKCLs) by femtosecond laser scanning
Authors: Anggraini Dian , Mubarok Wildan , Hosokawa Yoichiroh , Eto Koji , Suetsugu Shiro , Yalikun Yaxiaer 
Published: September 2022

Abstract
Immortalized megakaryocyte progenitor cell lines (imMKCLs) are multipotent cells which are used for the treatment of various blood diseases. One of the challenges in the expansion of imMKCLs is the sensitivity of the cells to the handling procedures, including the cell sorting process. In this study, we aimed to develop a reverse sorting system in which the non-target cells were detached by using femtosecond laser scanning. Using this system, a rapid cell sorting process with a high success rate of cell detachment was achieved. More importantly, the sorted target cells showed negligible changes in cell proliferation.
A Novel Spatial Gait Parameter-Based Vibrotactile Cueing for Freezing of Gait Mitigation Among Parkinson’s Patients
Authors: Khatavkar Rohan , TIWARI ASHUTOSH , Bhat Priyanka , Srivastava Achal , Kumaran S Senthil , Joshi Deepak 
Published: September 2022

<p> <em>Objective:</em> Auditory and visual cues have been shown to be efficacious in laboratory-based freezing of gait (FoG) mitigation in Parkinson’s disease (PD). However, the real-life applications of these cues are restricted due to inconvenience to the users and lower social acceptance. Recently developed closed loop vibrotactile cues based on temporal gait events have overcome the shortcomings of auditory and visual cueing. However, spatial gait parameter driven vibrotactile cueing has not been explored yet. Previous studies have suggested spatial gait parameter driven cueing to be more effective than temporal cueing based on FoG pathophysiology. Therefore, we developed and validated a novel cueing scheme in which foot to ground angle at heel strike (FGA_HS) is estimated using indigenous instrumented shoes to drive vibrotactile cueing. <em>Methods:</em> Eight PD freezers underwent a 6-meter timed walk test including reverse counting and hurdles to induce FoG. PD freezers underwent the protocol in the off-medication state with and without cue, and after medication without cue. Indigenous instrumented shoes were used for objective gait assessment. <em>Results:</em> Freezing severity, quantified by the ratio of time spent freezing to the total walking time, reduced with the cue in the off-medication state. The reduced freezing severity was accompanied by increased antero-posterior stance center of pressure excursion (CoP_AP) and FGA_HS. <em>Conclusion:</em> The novel spatial gait parameter-based cue was effective in mitigating FoG through improvement in associated gait parameters. <em>Significance:</em> With a future comprehensive validation on a larger number of participants, the novel cueing method has significant potential for practical use and commercialization.</p>
Purple Urine Bag Syndrome
Authors: Dharmawan Ade 
Published: September 2022

Purple Urine Bag Syndrome (PUBS) merupakan kasus yang jarang, namun dapat terjadi pada pasien dengan pemasangan kateter yang berkepanjangan, terutama pada keadaan imobilisasi. Kejadian PUBS dikaitkan dengan diet yang mengandung triptofan, urine yang bersifat alkali, konstipasi dan banyaknya bakteri yang menghasilkan sulfatase/fosfatase pada urine. Warna ungu yang terjadi disebabkan oleh adanya kombinasi pigmen indigo (warna merah) dan indirubin (warna biru) sebagai hasil metabolisme dari diet yang mengandung triptofan. PUBS biasanya tidak berbahaya namun sering membuat pasien cemas. Tatalaksana PUBS adalah dengan mengganti kateter urin dan pemberian antibiotik yang sesuai.
Implementation of Corporate Waqf Core Principles in the Development of Waqf in Indonesia
Authors: Huda Miftahul , Santoso Lukman 
Published: September 2022

The development of corporate waqf in Indonesia is relevant in creating an alternative model for the sustainability of waqf benefits and contributing to the national economic growth. This study aims to explore the implementation of Corporate Waqf Core Principles (CWCP), a set of sharia principles for corporate waqf implemented in the growth of waqf in Indonesia. This study uses qualitative research with a specific focus on comparative analysis of the advantages of waqf management at two different institutions that develop corporate waqf, Waqf Board Foundation of Universitas Islam Indonesia (YBW UII) Yogyakarta and Pesantren Tebuireng in Jombang. YBW UII Yogyakarta has developed productive waqf assets and immovable objects through professional and profitable multi-company institutions, ensuring that the waqf’s results expand and the benefits fly. Pesantren Tebuireng, on the other hand, understands the implementation of CWCP in the framework of productive waqf administration and management by conceptualizing the productivity of waqf assets through corporate and institutional management. The two models of waqf management methods ensure that waqf management within the corporate institutional framework is more productive and produces long-term outcomes and benefits. However, there are certain deviations in the implementation of the CWCP which has not used shares as waqf assets. The development of this waqf model in Indonesia can accelerate community economic development.

Received: 6 June 2022 / Accepted: 20 August 2022 / Published: 2 September 2022
Face-to-Display Work: Czech Managers’ Experiences and Expectations
Authors: Beňo Michal , Křížová Kateřina 
Published: September 2022

There has been a clear increase in the number of e-workers across countries and industries. But the experience of working from home has not been the same in all countries. The purpose of this quantitative study was to explore and understand the managers’ perspectives of and attitudes towards face-to-display working, namely the reactions of managers working from home, their use of the home-office during the ongoing Covid-19 epidemic, advantages and disadvantages, their productivity, how they cooperated and organised teleworking, and how they evaluated the reasons that led to their experience and their views on future home-office development. One hundred and sixty-two respondents from the Czech Republic participated in the online survey from February to March 2022. Eleven hypotheses were established that needed to be proved or disproved (six hypotheses were confirmed and five were not). Face-to-display working was identified as an effective, time-saving tool that fostered increased productivity and satisfaction (especially among the younger generation), promoted cost-saving and provided a future work model option. Conversely, management professionals were concerned that face-to-display working affected work-life balance and resulted in a lack of physical human interaction, also that productivity was not affected by less support from colleagues, by gender or by having an at-home work space and that workers were not spending more time at their desks. The findings from this study demonstrate positive social change involving the adoption of face-to-display working in businesses. Understanding the management perspective regarding face-to-display working in the Czech Republic may lead to ways of dealing with problems that will allow more employees to work in other premises.

Received: 23 May 2022 / Accepted: 16 August 2022 / Published: 2 September 2022
The Impact of Good Governance on Human Development in Jordan: A Case Study
Authors: Radaideh Ramzy M. H. 
Published: September 2022

This study investigates the correlations between indicators of good governance and human development in Jordan during the period (2010-2019). The study relies on the indicators of the World Bank for good governance and the Human Development Index for the United Nations Development Program (UNDP) about Jordan. It analyzes the indicators of the two variables in Jordan by employing statistical analysis. The study found that there are no statistically significant correlations between the indicators of good governance and human development at the significance level (0.05). It also found a weakness in the levels of good governance, and that there is a decline in the growth rates of human development during the studied period which may due to the negative impact of regional conditions related to the Arab Spring and its direct and indirect repercussions on the human development in Jordan. This indicates that human development in Jordan is affected by the consequences of regional conditions rather than just internal factors such as good governance. The study recommends the Jordanian government to build a productive national economy in a manner that reduces vulnerability to regional and international conditions, and provide support for education and health sectors, as well as to control high population growth rates.

Received: 26 May 2022 / Accepted: 17 August 2022 / Published: 2 September 2022
The Gender and Academic Year Difference among Vietnamese Undergraduates’ Attitude towards Decision Making Related to Solutions in Life
Authors: Le Ha Thi Thu , Phan Long Thanh , Pham Hoa Thi Thu 
Published: September 2022

Modern civilization is undergoing tremendous change at a breakneck pace, bringing both possibilities and difficulties to our everyday existence. Under these conditions, youngsters, particularly undergraduates, are frequently confronted with situations requiring them to make a choice. The ability to make decisions about many aspects of social life includes the following: medical, health, sexuality, mating, and professional route. As a result, education in decision making skills is critical in our era. This study was conducted with the major aims was to explore the differences in undergraduates’ attitude towards decision making skill regard of their genders and academic years. 697 individuals were randomly recruited from six colleges around the country using a random sample approach. According to the findings of our study, there was no statistically significant difference between the views of males and females, nor was there a statistically significant difference between the attitudes of freshmen and seniors.

Received: 19 June 2022 / Accepted: 20 August 2022 / Published: 2 September 2022
Improving Students Learning Strategy Trough Mobile Counselling Online Application
Authors: Fahyuni Eni Fariyatul , Taurusta Cindy , Hariastuti Retno Tri , Arifin Moch. Bahak Udin By 
Published: September 2022

This study aims to implement an online guidance and counselling service-based mobile counselling online application (MCO) to make it easier for students to recognize their learning potential and create effective learning strategies. Quantitative and qualitative data collection methods simultaneously compare the presence or absence of convergence, difference, or combination. The results of multivariate statistical analysis showed differences in self-efficacy and achievement between students who used online guidance and counselling services and those who used face-to-face guidance and counselling services. The MCO application results effectively increase the linkage of their learning potential with learning styles. They help develop, select, and plan effective learning strategies with individual and individual characteristics. The MCO application during the COVID-19 pandemic is an alternative for unlimited guidance and counselling services that can be anytime and with anyone.

Received: 11 July 2022 / Accepted: 24 August 2022 / Published: 2 September 2022