bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thrombotic thrombocytopenic purpura in pregnancy. Giving birth or not giving birth, that is the question
Authors: Galstyan G. M. , Shmakov R. G. , Klebanova Е. Е. , Troitskaya V. V. , Dvirnyk V. N. , Surin V. L. , Pshenichnikova O. S. , Pozdnyakova Yu. M. , Polushkina E. S. , Gaponova T. V. , Mamleeva S. Yu. , Pyregov A. V. , Rogachevskiy О. V. , Sysoeva E. P. , Tsvetaeva N. V. 
Published: April 2022

Introduction. Pregnancy is one of the most frequent triggers of congenital and acquired forms of thrombotic thrombocytopenic purpura (TTP).Aim — to develop tactics for the treatment of pregnant women with TTP.Results. TTP was associated with pregnancy in 55.5 % of all cases of TTP in women. In 5 pregnancies in which the diagnosis of TTP was known before pregnancy, or established in the early stages, TTP was treated throughout the pregnancy. In the congenital form, plasma transfusions were performed once every two weeks until the 20th week of pregnancy, or weekly, if thrombocytopenia < 150 × 109 /L persisted. Plasma transfusions were performed weekly after the 20th week with the goal of achieving clinical remission. With acquired TTP, glucocorticosteroids and plasma exchanges were used as treatment, in 1 case — rituximab, with the aim of achieving a clinical remission and an ADAMTS13 activity > 20 %. In this group of pregnant women, 1 caesarean section was performed and there were 4 cases of vaginal deliveries, with a total of 5 children being born with an average Apgar score of 7.5. In 7 pregnancies in which TTP fi rst manifested late, leading to a delayed diagnosis, preventive and curative measures were not carried out before delivery. In this group there were 2 abortions of pregnancy, 5 surgical deliveries, 3 cases of preeclampsia, 3 acute cerebral circulatory disorders, 1 intraabdominal bleeding, 1 case of acute renal failure, with two women undergoing mechanical ventilation. There was 1 case of antenatal fetal death, with a total of 4 children being born, who were assessed on the Apgar scale with an average of 5 points.Conclusion. Timely diagnosis as well as ongoing therapeutic and preventive measures help to avoid complications during childbirth in pregnant women with TTP.
Chimeric antigen receptor T-cell therapy in adult patients with B-cell lymphoproliferative diseases
Authors: Gavrilina O. A. , Galstyan G. M. , Shchekina A. E. , Kotova E. S. , Maschan M. A. , Troitskaya V. V. , Koroleva D. A. , Zvonkov E. E. , Fidarova Z. T. , Vasilyeva V. A. , Parovichnikova E. N. 
Published: April 2022

Introduction. The introduction of chimeric antigen receptor (CAR) T-cell therapy is a promising treatment of patients with relapsed or refractory (R/R) B-cell lymphoproliferative diseases (LPDs).Aim — to present the results of CAR-T-cell therapy of 6 adult patients with B-cell LPDs.Materials and methods. This is a pilot study conducted in adult patients with R/R or persistent minimal residual disease B-cell LPDs treated with CAR-T-cells. The study was approved by a local ethical committee of National Research Center for Hematology. Patients did not have alternative options for effective and safe treatment. All patients signed an informed consent. All patients were lymphodeplated with fl udarabine and cyclophosphamide for 4 days before the introduction of CAR-T-lymphocytes. Cytokine release syndrome (CRS) was prevented by tocilizumab on the day of CAR-T-cell administration. The effi cacy and safety of CAR-T-cell therapy was evaluated.Results. From 01.01.2020 to 01.01.2022, 10 CAR-T-cell infusions were performed for 6 adult patients (age 19–68 years, median — 32 years) with B-cell LPDs: 4 — R/R B-acute lymphoblastic leukemia, 1 — R/R diffuse large B-cell lymphoma, 1 — persistence of MRD in mantle cell lymphoma. In all patients with a R/R, median — 4 (2–5) lines of chemotherapy and/ or immunotherapy were performed before CAR-T-cell therapy. CD19 CAR-T-cells received 3 patients, CD19/CD22 CAR-Tcells — 2 patients, CD19 and CD20 CAR-T-cells received 1 patient. Autologous CAR-T-cells received 4 (66 %) patients, allogeneic CAR-T-cells received 1 patient, and one patient had two CAR-T-cell administrations — 1 autologous and 1 allogeneic. The median number of CAR-T-cells was 0.5 × 106 /kg (from 0.1 × 106 /kg to 3 × 106 /kg). In 7 (87.5 %) of the 8 cases after CAR-T-cell administration, overall response to therapy (complete or partial remission) was achieved, and complete remission was achieved in 6 (75 %) cases. Side effects were noted after 8 of 10 CAR-T-cell transfusions: CRS in 40 % (CRS 1 — 10 %, CRS 2 — 20 %, CRS 3 — 10 %), ICANS in 10 %, tumor lysis syndrome in 20 %, multi-organ dysfunction syndrome in 10 %. There were no lethal complications due to CAR-T-cell administrations. The median follow-up period was 6 (1–16) months. Of the 6 patients, 2 (33 %) died from relapses and progression of LPD. One (17 %) patient died in complete remission from infectious complications. Three (50 %) patients are observed till now. The median time of CAR-T-cell circulation was 33 (6– 60) days.Conclusion. CAR-T-cell therapy is a promising treatment for R/R B-cell LPDs and LPDs with persistence of MRD after cytoreductive therapy. This type of therapy requires a multidisciplinary approach.
Single-shot chirped pulse digital holography for observing the propagation of ultrafast optical pulses in liquid
Authors: Karasawa Naoki , Ishikawa Tomohiro , Sugo Rika 
Published: April 2022

Abstract
The propagation of intense ultrafast optical pulses in liquid was observed using single-shot chirped pulse digital holography for measuring the sequence of ultrafast optical wavefronts. In this method, two non-collinear ultrafast object pulses and a chirped reference pulse were interfered to record the digital hologram of optical wavefronts at two different times. The phase difference images of the propagation of intense optical pulses in water as well as carbon disulfide separated by 0.67 ps were obtained and the densities of generated plasma were estimated.
Low-pressure acidic ammonothermal growth of 2-inch-diameter nearly bowing-free bulk GaN crystals
Authors: Kurimoto Kouhei , Bao Quanxi , Mikawa Yutaka , Shima Kohei , Ishiguro Toru , Chichibu Shigefusa F. 
Published: April 2022

Abstract
Seeded growth of 2-inch-diameter GaN crystals via low-pressure (∼100 MPa) acidic ammonothermal method is demonstrated. Nearly bowing- and mosaic-free GaN crystals exhibiting full-width at half-maximum values for the 0002 X-ray rocking curves below 20 arcsec were achieved on high lattice coherency c-plane SCAATTM seeds with gross dislocation densities in the order of 104 cm−2. The photoluminescence spectra of the grown crystals exhibited a predominant near-band-edge emission at 295 K, of which intensity was one order of magnitude higher than the characteristic deep-state emission bands. A nearly bowing-free 60 mm × 60 mm c-plane GaN crystal was eventually obtained.
توظيف الوثيقة التاريخية في كتابات الشيخ سلطان بن محمد القاسمي(نماذج مختارة)
Authors: حياز خولة , شترة خير الدين 
Published: April 2022

تهدف الدراسة إلى تناول إشكالية رئيسة تتمحور في أهمية الوثيقة في مؤلفات المؤرخ سلطان القاسمي لدورها البارز في أغلب مؤلفاته التاريخية، من خلال دراسة نماذج مختارة من مؤلفاته والتي اعتمد فيها على الوثيقة بصورة شبه كاملة، وذلك لمحاولة إيجاد إجابة عن التساؤلات الآتية: كيف وظّف المؤرخ سلطان القاسمي الوثيقة التاريخية في كتاباته؟ وهل طبق منهج النقد التاريخي على الوثائق التي استخدمها؟ وما الغاية التي سعى إلى تحقيقها من وراء استخدامه لها؟ وما أبرز الصعوبات التي واجهته؟ وللإجابة على هذه التساؤلات اعتمدت الدراسة على نماذج مختارة من مؤلفات المؤرخ سلطان القاسمي التاريخية، وفق منهج استدلالي يهدف إلى التعرف على جزئيات أبحاثه التاريخية، قصد تحديد العلاقات التي تربط بينها وبين مصادره الأرشيفية، وكذا مدى توافقها واتساقها مع الإطار العام لحركية المواضيع التاريخية التي درس وبحث فيها.
حالات الحكم بالإبعاد القضائي في التشريع الإماراتي "دراسة مقارنة"
Authors: الخيلي جمعة , العاني محمد , النوايسه عبدالإله 
Published: April 2022

تبين لنا من دراسة موضوع حالات الإبعاد القضائي، بأنه موضوع يحظى بأهمية قانونية في مجال قانون العقوبات الاتحادي والتشريعات الجنائية الخاصة في دولة الإمارات العربية المتحدة، باعتباره جزاءً جنائياً قاسياً على الشخص الأجنبي الذي يدان بارتكاب جريمة معينة على أراضي دولة الإمارات التي يقيم فيها. وعليه فإن محل جزاء الإبعاد القضائي يكون الشخص الأجنبي الذي يرتكب إحدى الجرائم المنصوص عليها في كافة القوانين الجزائية الإماراتية. وأن القضاء الإماراتي هو الذي حدد ويقدر جسامة الخطورة الإجرامية التي يترتب عليها حكم تدبير الإبعاد.
وقد فرق المشرع الاتحادي بين نوعين من الإبعاد القضائي، وهما: الإبعاد القضائي الوجوبي، والإبعاد القضائي الجوازي. ففي الحالة الأولى حدد جملة من حالات الحكم بتدبير الإبعاد، وأوجب على المحكمة أن تأمر بإبعاد الأجنبي المحكوم عليه بعقوبة مقيدة للحرية في جميع الجنايات، ومنها الجنايات الواقعة على العرض والجرائم الماسة بأمن الدولة وجريمة الإضراب والجرائم الماسة بالعقائد والشعائر الدينية، هذا بالإضافة إلى بعض الحالات الأخرى الواردة في تشريعات جزائية خاصة نصت عليها قوانين عديدة، كقانون دخول وإقامة الأجانب وقانون مكافحة المواد المخدرة والمؤثرات العقلية وقانون جرائم مكافحة تمويل الإرهاب والاتجار بالبشر وقانون أحداث الجانحين والمشردين.
لوائح الضرورة في التنظيم الدستوري الإماراتي (دراسة مقارنة)
Authors: الكندي ريم , النجيفي مصطفى 
Published: April 2022

تلجأ الدول الى منح رئيس الدولة صلاحية تشريع استثنائية تسمى بلوائح الضرورة، والتي اختلفت الآراء في تعريفها وشروط تطبيقها وطبيعتها، وكيفية إصدارها والرقابة عليها.
ومشكلة البحث تدور حول مخالفة شروط وضوابط إصدار لوائح الضرورة؟ وأثر إقرارها من عدمه أو المدة الزمنية اللازمة أو فوات المدة القانونية لعرضها على المجلس الأعلى للاتحاد، أو حالة سكوته، أو فترة تأجيل أو حل البرلمان، وما أثر ذلك على الحقوق المكتسبة للأفراد.
وقد إتبعنا أسلوب المنهج الوصفي والتحليلي الدستوري المقارن في كل من دولة الامارات العربية ومصر وفرنسا.
وقسمنا البحث الى ثلاث مباحث، الأول التعريف بلوائح الضرورة والأساس الفقهي والدستوري لها، وفي الثاني شروط إصدار لوائح الضرورة وموقف الفقه من التنظيم الدستوري لها، وطبيعتها القانونية وفي الثالث الرقابة البرلمانية والقضائية وأثارها، ثم خاتمة البحث التي تضمنت النتائج والتوصيات.
Analisis Keterlibatan Belajar Siswa Secara Online
Authors: Gusrina Anggi , Sihombing Hulga Ryan Shori , Sitompul Uswatun Hasanah , Nasution Inom 
Published: April 2022

Pembelajaran secara daring atau online menciptakan permasalahan baru dan bentuk beban yang baru dalam teknik pendidikan yang berbeda. Dikarenakan media hingga metode yang disajikan dalam pembelajaran akan berpengaruh besar terhadap hasil belajar siswa atau peserta didik. Tujuan penelitian ini untuk menganalisa dalam keterlibatan siswa atau peserta didik serta hambatan yang dilalui mereka dalam menjalankan pembelajaran secara online. Jenis penelitian yang digunakan adalah penelitian kualitatif yang dimana bersifat lebih deskriptif, dengan subjek para peserta didik 1 hingga 6 SD Negeri 013864 tepatnya di Desa Lubuk Palas dusun II, dan tingkat Mts Al-washliyah punggulan Air joman kelas 8-9 dan tenaga pendidik dan kependidikan yang mengajar di tingkat SD/MI, SMP/MTS hingga SMA/SMK serta sejumlah masyarakat yang anak-anaknya masih mengemban pendidikan dan melakukan proses pembelajaran secara daring atau online. Adapun pengumpulan data melalui dua macam angket keterlibatan dan hambatan peserta didik yang diperkuat dengan wawancara, observasi dan kajian dokumentasi penelitian yang dilakukan sebelumnya oleh para ahli, sedangkan untuk analisis data yang digunakan adalah kualitatif berdasarkan hasil wawancara, observasi dan kajian dokumentasi penelitian yang dilakukan. Hasil dari penelitian ini adalah keterlibatan peserta didik atau siswa dalam pembelajaran secara online atau daring cukup memperlihatkan keterlibatan dan pengaruh yang ada, yang tanpa disadari dan kurangnya kesadaran dan cekatan dalam penanganan kendala atau hambatan yang dialami para peserta didik atau siswa. Pelaksanaan pembelajaran secara online pada peserta didik, tidak mencapai target yang diinginkan dalam dunia pendidikan dikarenakan banyaknya hambatan yang dilalaikan atau dibiarkan. Meskipun pembelajaran secara online dapat dilakukan dimana saja, dan kapan saja. Namun, respon dan pemahaman siswa atau peserta didik menurun akibat tidak memperhatikan poin-poin pengaruh yang perlu diperhatikan dalam pembelajaran secara online atau daring
Implementasi Hadis dalam Membentuk Karakter Siswa di SDIT Madani Parung Panjang Pada Pembelajaran PAI
Authors: Fauziah Fauziah , Elisa Elisa , Indrawati Dewi 
Published: April 2022

Pendidikan karakter adalah proses transfer keilmuan yang dimaksudkan untuk membangun peserta didik menjadi pribadi yang mandiri, bertanggung jawab dan percaya diri dalam kehidupannya sehari-hari. Pendidikan dan pembinaan karakter peserta didik seyogyanya menjadi yang utama, karena pribadi peserta didik akan menjadi wajah dari Lembaga pendidikan tersebut, terlepas dari baik atau buruknya kepribadian peserta didiknya. di antara berbagai cara yang relevan untuk meningkatkan karakter peserta didik adalah dengan mempelajari hadis tentang kemandirian, yang mana pelajaran hadis tersebut sudah teruji dapat meningkatkan kemandirian, tanggung jawab dan percaya diri peserta didik yang diperagakan oleh para guru sebagai contoh dan suri teladan mereka. Tujuan dari penelitian ini adalah untuk mengetahui keefektifan pembelajaran hadis dalam membangun karakter peserta didik di SDIT Madani Parung Panjang, Bogor. Penelitian ini menggunakan pendekatan kualitatif yang diperoleh dari hasil wawancara, pengumpulan data dan angket. Hasil penelitian menunjukkan bahwa: 1. Pembelajaran hadis dikelas III sangat relevan bagi keseharian peserta didik, 2. Peserta didik cenderung lebih disiplin, 3. Peserta didik mampu membedakan antara sesuatu yang baik dan buruk.
Epidemiology and Surgical Outcome of Traumatic Sub Axial Cervical Spine Injuries in a Tertiary Care Hospital of KPK, Pakistan
Authors: Tahir Hamayun , Naseer Hassan  , Afzal Raza  , Hina Arooj  , Samina Feroz  , Farooq Azam  
Published: April 2022

Objective: The purpose of this study was to characterize the epidemiologic characteristics, a pattern of traumatic subaxial cervical spine injuries, and their surgical outcomes in a tertiary care hospital in Khyber Pakhtunkhwa, Pakistan.
Materials and Methods: This retrospective descriptive study was conducted at the Department of Neurosurgery at Lady Reading Hospital Peshawar. The records of 40 patients between the ages of 15 and 60 who had cervical spine injuries were evaluated to characterize the injuries and surgical outcomes. We employed the anterior route for surgery regularly and the posterior method only when the reduction failed or substantial instability. We used a tricortical bone graft or titanium cages with autologous bone and secured them through titanium plates to achieve fusion.
Results: 80% of patients presented with sub axial cervical injury. Regarding the etiology of injury, 37.5 % had motor vehicle accidents, 28.12% had a history of height falls, and the remaining had sustained injuries due to other causes. The majority of the patients, 68.75% (n = 22), had isolated subluxation injury.87.5% (n = 28) underwent surgical intervention; surgical outcomes such as pain relief were measured using the VAS, which was 6.09 ± 1.42 preoperatively while 4.5 ± 1.29 postoperatively with a difference of means of 1.59. There was a significant improvement in neurological functions as measured through the ASIA impairment scale.
Conclusion: Most cervical spine injuries occurred in young male patients, motor vehicle accidents were the most prevalent cause, and isolated subluxation was the most frequent injury pattern.
Comparison of the Efficacy of Multi Dural Stab Craniectomy with Open Dural Flap Craniectomy in Patients Having Acute Subdural Hematoma
Authors: Wahab Anum , Asghar Inamullah , Rehman Muhammad Abdur , Anwar Taimoor , Hussain Muhammad Akmal 
Published: April 2022

Background/Objective: We compared the efficacy of multi-dural stab craniectomy with open dural flap craniectomy in patients having acute subdural hematoma.
Materials and Methods: A randomized controlled trial was conducted in the Department of Neurosurgery, Allied hospital, Faisalabad. 70 patients having acute subdural hematoma were included. All of the patients were randomized in two groups: group A received a multi-dural stab craniectomy, while group B received an open dural flap craniectomy. Efficacy was assessed after 3 months of treatment in terms of a good recovery.
Results: Out of 70 patients, the mean age was 34.51 ± 8.712 years. Because of similar age and presenting GCS, the data show a non-significant difference in clinical outcomes between patients undergoing multi dual stab and open dural flap operations. However, a significant difference between the clinical results occurred at 3 months after the surgery (p-value 0.004). The efficacy of the multi-dural stab procedure was significantly higher from the open dural flap surgery (p-Value 0.006). The efficacy of the multi-dural stab surgery was significantly higher in the under 35 years age group of patients compared to open dural flap surgery. The results highlight those better results were seen in both surgeries when the presenting GCS of patients was higher (GCS= 6 – 8) compared to poor outcomes in patients with GCS of less than 5/15.
Conclusion: Multi-dural stabs are a safer alternative to the open dural flap for removing acute SDH with satisfactory recovery.
A Study of 90 GHz Dust Emissivity on Molecular Cloud and Filament Scales
Authors: Lowe Ian , Mason Brian , Bhandarkar Tanay , Clark S. E. , Devlin Mark , Dicker Simon R. , Duff Shannon M. , Friesen Rachel , Hacar Alvaro , Hensley Brandon , Mroczkowski Tony , Naess Sigurd , Romero Charles , Sadavoy Sarah , Salatino Maria , Sarazin Craig , Orlowski-Scherer John , Schillaci Alessandro , Sievers Jonathan , Stanke Thomas , Stutz Amelia , Xu Zhilei 
Published: April 2022

Abstract
Recent observations from the MUSTANG2 instrument on the Green Bank Telescope have revealed evidence of enhanced long-wavelength emission in the dust spectral energy distribution (SED) in the Orion Molecular Cloud (OMC) 2/3 filament on 25″ (0.1 pc) scales. Here we present a measurement of the SED on larger spatial scales (map size 0.°5–3° or 3–20 pc), at somewhat lower resolution (120″, corresponding to 0.25 pc at 400 pc) using data from the Herschel satellite and Atacama Cosmology Telescope (ACT). We then extend the 120″-scale investigation to other regions covered in the Herschel Gould Belt Survey (HGBS), specifically the dense filaments in the southerly regions of Orion A, Orion B, and Serpens-S. Our data set in aggregate covers approximately 10 deg2, with continuum photometry spanning from 160 μm to 3 mm. These OMC 2/3 data display excess emission at 3 mm, though less (10.9% excess) than what is seen at higher resolution. Strikingly, we find that the enhancement is present even more strongly in the other filaments we targeted, with an average excess of 42.4% and 30/46 slices showing an inconsistency with the modified blackbody to at least 4σ. Applying this analysis to the other targeted regions, we lay the groundwork for future high-resolution analyses. Additionally, we also consider a two-component dust model motivated by Planck results and an amorphous grain dust model. While both of these have been proposed to explain deviations in emission from a generic modified blackbody, we find that they have significant drawbacks, requiring many spectral points or lacking experimental data coverage.
An Open-source Bayesian Atmospheric Radiative Transfer (BART) Code. II. The Transit Radiative Transfer Module and Retrieval of HAT-P-11b
Authors: Cubillos Patricio E. , Harrington Joseph , Blecic Jasmina , Himes Michael D. , Rojo Patricio M. , Loredo Thomas J. , Lust Nate B. , Challener Ryan C. , Foster Austin J. , Stemm Madison M. , Foster Andrew S. D. , Blumenthal Sarah D. 
Published: April 2022

Abstract
This and companion papers by Harrington et al. and Blecic et al. present the Bayesian Atmospheric Radiative Transfer (bart) code, an open-source, open-development package to characterize extrasolar planet atmospheres. bart combines a thermochemical equilibrium abundance (tea), a radiative transfer (Transit), and a Bayesian statistical (mc3) module to constrain atmospheric temperatures and molecular abundances for given spectroscopic observations. Here we describe the Transit radiative transfer package, an efficient line-by-line radiative transfer C code for one-dimensional atmospheres, developed by P. Rojo and further modified by the UCF exoplanet group. This code produces transmission and hemisphere-integrated emission spectra. Transit handles line-by-line opacities from HITRAN, Partridge & Schwenke (H2O), Schwenke (TiO), and Plez (VO) and collision-induced absorption from Borysow, HITRAN, and ExoMol. Transit emission spectra models agree with models from C. Morley (private communication) within a few percent. We applied bart to the Spitzer and Hubble transit observations of the Neptune-sized planet HAT-P-11b. Our analysis of the combined HST and Spitzer data generally agrees with those from previous studies, finding atmospheric models with enhanced metallicity (≳100× solar) and high-altitude clouds (≲1 mbar level). When analyzing only the HST data, our models favor high-metallicity atmospheres, in contrast with the previous analysis by Chachan et al. We suspect that this discrepancy arises from the different choice of chemistry modeling (free constant-with-altitude versus thermochemical equilibrium) and the enhanced parameter correlations found when neglecting the Spitzer observations. The bart source code and documentation are available at https://github.com/exosports/BART.
An Open-source Bayesian Atmospheric Radiative Transfer (BART) Code. III. Initialization, Atmospheric Profile Generator, Post-processing Routines
Authors: Blecic Jasmina , Harrington Joseph , Cubillos Patricio E. , Oliver Bowman M. , Rojo Patricio M. , Stemm Madison , Challener Ryan C. , Himes Michael D. , Foster Austin J. , Dobbs-Dixon Ian , Foster Andrew S. D. , Lust Nathaniel B. , Blumenthal Sarah D. , Bruce Dylan , Loredo Thomas J. 
Published: April 2022

Abstract
This and companion papers by Harrington et al. and Cubillos et al. describe an open-source retrieval framework, Bayesian Atmospheric Radiative Transfer (BART), available to the community under the reproducible-research license via https://github.com/exosports/BART. BART is a radiative transfer code (transit; https://github.com/exosports/transit; Rojo et al.), initialized by the Thermochemical Equilibrium Abundances (TEA; https://github.com/dzesmin/TEA) code (Blecic et al.), and driven through the parameter phase space by a differential-evolution Markov Chain Monte Carlo (MC3; https://github.com/pcubillos/mc3) sampler (Cubillos et al.). In this paper we give a brief description of the framework and its modules that can be used separately for other scientific purposes; outline the retrieval analysis flow; present the initialization routines, describing in detail the atmospheric profile generator and the temperature and species parameterizations; and specify the post-processing routines and outputs, concentrating on the spectrum band integrator, the best-fit model selection, and the contribution functions. We also present an atmospheric analysis of WASP-43b secondary eclipse data obtained from space- and ground-based observations. We compare our results with the results from the literature and investigate how the inclusion of additional opacity sources influences the best-fit model.