bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seismic Texture of Tertiary Successions: Insights from Tipam and Barail Formations in the Upper Assam Basin, NE India
Authors: Kumar Priyadarshi Chinmoy , Sain Kalachand 
Published: December 2022

ABSTRACT
This work uses high-quality 3D seismic data from the historic oil-producing province of NE India in the Upper Assam Basin for the investigation of structural architecture and textural characteristics that have modulated the Barail and Tipam Formations of the Tertiary successions. The seismic volume was structurally conditioned to improve the contrast at seismic reflectors and thereby preserving their lateral continuity. The conditioned data are interpreted in combination with seismic attributes to examine the seismic textural responses in the interval of interest between the Barail and Tipam formations. The study brings out that the Barail coal-shale unit is associated with deformed, wavy, chaotic and heterogeneous textures, which suggest a deeper basinal condition prevailing during the deposition. However, molassic texture associated with less chaotic and high homogeneity of reflections indicate the occurrence of fluviatile environment that prevailed during the deposition of the Tipam sandstone unit. It is observed that structural compartments within the Miocene interval act as different trap networks for encasing migrated hydrocarbons from the Oligocene source interval. The finding establishes a relationship between the structural and depositional set-ups within the litho-units of the Tertiary successions for plausible hydrocarbon accumulation in the upper Assam basin.
Hydrothermal from – Geology to Nanotechnology and Nanogeoscience (Part - II)
Authors: Namratha K. , Nayan M.B. , Pandareesh M.D. , Basavarajappa H.T. , Byrappa K. 
Published: December 2022

Abstract
Hydrothermal process from a pure geologic science has now become one of the fast-emerging processing technologies to synthesize nanomaterials in the laboratory. Today it is an advanced technological tool, which facilitates to obtain nanomaterials and nanoparticles with desired size, shape, quality and functionality. In fact, hydrothermal technique has its bearing on the nature-inspired or geo-mimetic processes that are being employed extensively in the laboratory. The natural hydrothermal processes are acting ever since earth came into existence, and leading to the formation of a large variety of minerals, rocks and ores. Earth is a blue planet of the universe, where water is a major component which plays an important role in the formation of geological materials and hydrothermal circulation has always assisted by bacteria, photochemical and other related activities. The synthesis of advanced technological materials often occurs in the presence of biomolecules, proteins, organic ligands, DNA and amino acids. An understanding of nanogeoscience is becoming very relevant in the current context and is crossing into almost all the branches of geology including palaeoecology, mineralogy, environmental geology, energy geology, geochemistry, etc. Similarly, the hydrothermal processes in nature cover several branches of geology whether it is the origin of ores, minerals, rocks, but also life on the earth. In the present review, the authors discuss all the above aspects in detail with a future perspective of the field. Also, the authors have described the evolution of hydrothermal process from pure geology to the nanotechnology, nanogeoscience, nano-geopolymers, etc., with specific examples and depicted its relevance to the geologic science.
Subsurface Expressions of the Aravalli-Delhi Fold Belt in the Western Ganga Basin by Magnetotellurics
Authors: Manglik Ajay , Suresh M. , Nagarjuna Danda , Pavankumar G. , Demudu Babu M. , Chakravarthi N.N. , Kandregula Raj Sunil 
Published: December 2022

Abstract
The Aravalli-Delhi fold belt (ADFB) in the NW Indian shield is associated with moderate level of seismicity, including the seismicity of the Delhi seismic zone (DSZ). Several studies have postulated northward extension of the ADFB beneath the alluvium cover of the Ganga basin and its existence beneath the Himalaya. However, subsurface disposition of the ADFB north of Delhi has not been mapped in detail. The results of a recent magnetotelluric study carried out along a profile between Kaithal and Bareilly across the inferred northward extension of the ADFB is presented to address this issue. The results reveal that the concealed ADFB consists of a collage of nearly vertical conductive and resistive blocks buried beneath about 1 to 1.3 km thick alluvial sediments. The boundaries of major inferred tectonic features, such as the western boundary of the Delhi-Haridwar ridge (DHR) and the Great Boundary Fault (GBF), as well as the locations of the Ganga and the Yamuna rivers coincide with such steep contacts. The results suggest the presence of some more concealed geological contacts/tectonic boundaries for which no corresponding surface tectonic features have been mapped. Such a configuration of nearly vertical conductive and resistive blocks has significant implications for the studies aimed at earthquake hazard assessment of the region, especially the DSZ. These results, in conjunction with the MT models available for the Garhwal Himalaya, also indicate continuation of these blocks beneath the Kumaun-Garhwal Himalaya (KGH). Thus, the crust of the KGH below the Main Himalayan Thrust should be highly heterogeneous spatially.
Kuwari Lake: Potentially Dangerous for Landslide Lake Outburst Flood (LLOF)
Authors: Bisht M.P.S. , Bisht Hemant , Luirei Khayingshing , Mehta Manish , Kumar Vinit 
Published: December 2022

Abstract
Here a report of a lake of about one km in length that resulted from damming of a river by landslide near Kuwari village at the altitude of 1733 m asl and located between N 30o 5' 16"- 30o 5' 16" and E 79o 48' 30" - 79o 48' 29". On the basis of Google Earth images, it has been observed that a huge landslide took place from 16th to 17th June, 2013 and also in 2019 (as per the local sources) that blocked the Shambhu Gad (Baura Gad) in Bageshwar district and formed a huge lake, which covered ~15666 m2 area. It was also observed that an old landslide was reactivated due to cloud burst or toe erosion and affected an area ~862913 m2 between 2664 and 1761 m asl. The area affected by the landslide is ~4 km, the maximum width is about 650 m. In the vicinity of Kuwari village the impact of this Kuwari landslide also observed in the Jhaliya village (district Chamoli) established over south facing slope in the right bank of Pinder river. Both the villages are separated by E-W trending ridge (3700 m asl).
Integrated Multivariate Analysis, Hydrogeochemical Modelling and Speciation Studies to Reveal Geogenic Origins behind Physical Disabilities: A Case Study in Pure Village, Varanasi, India
Authors: Singh P. K. , Singh S. K. , Debnath Sampriti , Dutta Archisman 
Published: December 2022

Abstract
The study aims to discuss elaborately about the origin of physical disabilities amongst the locals of Pure village in Varanasi district, India through proper hydrogeochemical facies, multivariate statistics and correlations, saturation indices of mineral phases, speciation of heavy metals, radiation surveys, and comparing the values of major ions and heavy metals with respect to the permissible limits of USEPA, WHO, ICRP, and BIS standards. The evolution of water is Ca-Mg-HCO3 type, as evident from Piper trilinear plot, with neutral to feeble alkalinity. From Gibbs’s diagram, origin of major ions in groundwater is found primarily to be chemical weathering of the rock forming minerals as all the samples fall in rock dominance zone. Mineral saturation indices modelling by PHREEQC suggest supersaturation of water with goethite, hematite, Fe(OH)3(a), and dolomite. Speciation studies of PG-4 having high U concentration (13 μg/l) reveal dominance of U4+ and Fe2+ species, thus confirming reducing environment in aquifer. The high concentration of iron minerals in water promotes adsorption of U4+ on their matrices thus reducing effective U concentration in water. The U values are higher in most of the drinking water samples as per safe limits indicated by ICRP and WHO suggesting that long-term use for drinking purpose may cause serious health crisis. Higher Sr values (119 ± 39 μg/l) in groundwaters, greater than minimum reporting level, as per USEPA, may be one of the contributing factors for physical disabilities of inhabitants.
Flood Frequency Analysis: A Case Study of Pohru River Catchment, Kashmir Himalayas, India
Authors: Ahad Ummar , Ali Ummar , Inayatullah Meer , Shah Abdul Rauf 
Published: December 2022

Abstract
Planning, design, and management of hydraulic structures such as barrages, dams, spillways, and bridges all need estimation of Peak Flood Discharge for a desired return time. The findings of a research, examining the frequency of Pohru river floods using the Gumbel’s distribution and Log Pearson type III approaches, widely used models in hydrological studies for the probability distribution to simulate stream flows, are presented in this work. For a period of two decades, the approach has been used to predict the yearly maximum discharge of the river from (1998 to 2018). The analysis also reveals that the observed and anticipated peak discharges of the Log Pearson type III (LP3) and Gumble (EV1) models have a positive correlation (R2 = 0.71) and (R2 = 0.52). As a result, the best-fit models for modeling and flood frequency analysis of yearly peak flows on the Pohru River are the LP3 and G(EV1). Peak flood values for 2, 5, 10, 25, 50, 100, 200, and 500 year return periods were also determined using the same approach, which might be valuable for flood management in the area.
SPI1 is a prognostic biomarker of immune infiltration and immunotherapy efficacy in clear cell renal cell carcinoma
Authors: Feng Huayi , Wang Tao , Ye Jiali , Yang Yang , Huang Xing , Lai Dong , Lv Zheng , Huang Yan , Zhang Xu 
Published: December 2022

Abstract
Background
Spi-1 proto-oncogene (SPI1), which encodes an ETS-domain transcription factor, can activate gene expression in myeloid and lymphoid lineages. The role of SPI1 in the tumor immune microenvironment in clear cell renal cell carcinoma (ccRCC) remains unknown. In this study, we investigated the possible role of SPI1 in ccRCC using an independent cohort and a comprehensive bioinformatics analysis.

Materials and methods
Quantitative real-time PCR, western blot and immunohistochemistry assays were used to compare the SPI1 expression levels between ccRCC tissues and normal tissues, analyze the relationships between SPI1 and CD68, CD8, CD4 expression levels, and explore the link between SPI1 and the efficacy of immunotherapy in our cohort. Tumor Immune Estimation Resource, UALCAN, cBioPortal, TISIDB database, and LinkedOmics database were used in our study.

Results
SPI1 expression level was higher in ccRCC bulk tissues than in normal bulk tissues. SPI1 was an independent prognostic factor for poor overall survival and progression-free survival in patients with ccRCC. SPI1 expression was strongly related to the infiltration of immune cells and immune-related molecules. SPI1 was more highly expressed in tumor-infiltrating immune cells rather than in cancer cells. Non-responders to immunotherapy against ccRCC were more likely to express higher SPI1 levels than responders. Genes co-expressed with SPI1 primarily correlated with immune-related pathways.

Conclusions
SPI1 expression in tumor bulk tissues is associated with disease progression and poor prognosis, as well as high expression levels of immune markers and infiltration of immune cells. SPI1 can be used as a prognostic biomarker to monitor and evaluate immunotherapy efficacy.
An improved method for the production of biogenic silica from cornhusk using sol–gel polymeric route
Authors: Prempeh Clement Owusu , Formann Steffi , Hartmann Ingo , Nelles Michael 
Published: December 2022

AbstractPorous silica was synthesized from cornhusk using the sol–gel polymeric route and compared with ash obtained from the direct combustion process under laboratory conditions. The unmodified ash from the direct combustion process was dissolved in NaOH for 1 h to form sodium silicate, which was subsequently hydrolyzed with citric acid to yield a silica xerogel. The obtained xerogel was characterized using inductively coupled plasma–optical emission spectrometry (ICP-OES), Fourier transforms infrared (FTIR) spectroscopy, X-ray diffraction (XRD), simultaneous thermal analysis (STA), gas sorption techniques to determine their elemental constituents, functional groups, crystalline phases, thermal stability, and porosity, respectively. The results showed that the synthesized silica xerogel exhibited porous network structures with a high-specific surface area and mesopore volume of 384 m2/g and 0.35 cm3/g, respectively. The pore size distribution revealed a complete transformation of the pore network structures of the unmodified ash from a monomodal to a bimodal pore system, with micro- and mesopore peaks centered around 1.5 and 3.8 nm, respectively. The ICP-OES results showed that the silica content significantly increased from 52.93 to 91.96 wt.% db after the sol–gel treatment. XRD diffraction confirmed the amorphicity of the silica particles obtained from the sol–gel extraction method. In addition, the STA data showed that the silica xerogel has high thermal stability compared to the unmodified ash, as the latter exhibited poor thermal stability and low textural properties. The high surface area and narrow pore cavity size distribution of the porous silica xerogel make it an ideal substrate for catalysts and an excellent template for growing other nanoparticles within the pores.
Knockdown of lncRNA-ASLNC12002 alleviates epithelial–mesenchymal transition of type II alveolar epithelial cells in sepsis-induced acute respiratory distress syndrome
Authors: Feng Kaixuan , Huang Weifeng , Shang Jiawei , Ping Feng , Tan Qin , Wang Wei , Li Yingchuan , Cao Yongmei 
Published: December 2022

AbstractPatients with sepsis-induced acute respiratory distress syndrome (ARDS) have higher mortality and poor prognosis than pneumonia-induced ARDS. Pulmonary fibrosis is an irreversible accumulation of connective tissue in the interstitium of the lung and closely associated with the epithelial–mesenchymal transition (EMT) of type II alveolar epithelial cells (AECIIs). Therefore, it is undoubtedly worth studying whether the EMT of AECIIs in sepsis-induced ARDS patients is different from that in patients with pneumonia-induced ARDS in the regulatory mechanism. Here, we will report for the first time that an lncRNA-ASLNC12002 is highly expressed in AECIIs of patients with sepsis-induced pneumonia and promotes EMT in AECIIs. The research results showed that the expression of ASLNC12002 in AECIIs derived from patients with sepsis-induced ARDS is significantly higher than that in normal people and pneumonia-induced ARDS patients. Mechanism research showed that ASLNC12002 can cause the inactivation of the anti-EMT pathway NR2F2/miR128-3p/Snail1 by acting as the sponge of miR128-3p. Functional experiments showed that targeted silencing of ASLNC12002 could effectively inhibit EMT progression in AECIIs of patients with sepsis-induced pneumonia by restoring NR2F2/miR128-3p/Snail1 pathway. In a word, our study shows for the first time that the inactivation of NR2F2/miR128-3p/Snail1 pathway caused by the enhanced expression of ASLNC12002 is the direct reason why AECIIs in sepsis-induced ARDS patients are prone to get EMT progress. ASLNC12002 has the potential to become a biological target for the prevention and treatment of pulmonary fibrosis in patients with sepsis-induced ARDS. At the same time, the expectation that ASLNC12002 and its related products may be used as clinical markers for the evaluation of early pulmonary fibrosis in ARDS patients should not be ignored.
Neural network fusion with fine-grained adaptation learning for turnover prediction
Authors: Xue Xia , Sun Xia , Wang Hongyu , Zhang Hao , Feng Jun 
Published: December 2022

AbstractTurnover prediction has an important impact on alleviating the brain drain, which can help organizations reduce costs and enhance competitiveness. Existing studies on turnover are mainly based on analyzing the turnover correlation, using different models to predict various employee turnover scenarios, and only predicting turnover category, while the class imbalance and turnover possibility have been ignored. To this end, in this paper, we propose a novel fine-grained adaptation-based turnover prediction neural network (FATPNN) model. Specifically, we first employ a GRU to learn profile-aware features representations of the personnel samples. Then, to evaluate the contribution of various turnover factors, we further exploit an attention mechanism to model the profile information. Finally, we creatively design a weighted-based probability loss function suitable for our turnover prediction tasks. Experimental results show the effectiveness and universality of the FATPNN model in terms of turnover prediction.
Synthesis and catalytic behavior of FCC catalysts obtained from kaolin by the in-situ method
Authors: Padilla Jessyka , Guzman Alexander , Poveda-Jaramillo Juan Carlos 
Published: December 2022

AbstractIn-situ zeolites NaY and Na[B]Y were synthesized on microspherical matrices of kaolin to obtain FCC catalysts. An alkaline pretreatment of the matrix was investigated in order to evaluate its effect on matrix properties and crystallization of the in-situ synthetized zeolites. Catalysts were characterized by SEM, TEM, Ar adsorption, XRD and NH3-TPD. It was observed an increase in the surface area and mesoporosity of the alkaline treated catalysts either synthetized with the presence of boron or with no boron in the hydrothermal reaction mixture. Ammonia TPD analyses have shown an increase in the amount and strength of the acidity of the catalysis with the zeolites crystallized on the pretreated matrices and exchanged with lanthanum ions. Thus, a combination between higher concentration of stronger acid sites and higher proportion of mesoporous generated in the matrices treated with alkaline solution had resulted in more active catalyst as shown by the triisopropylbenzene cracking experiments conducted here.
Graphical abstract
Accelerating diversity, equity, and inclusion goals: a qualitative assessment from the lens of scientists at the 2020 Clinical Translational Science Awards Annual Meeting
Authors: Fernandez Claudia S.P. , Taylor Monica M. , Dave Gaurav , Brandert Kathleen , Mollenkopf Katherine , Larkin Suzanna , Corbie Giselle 
Published: December 2022

Abstract
Participants in the leadership breakout session at the Clinical Translational Science Awards (CTSA) virtual 2020 conference discussed and ranked six recommendations in terms of feasibility, impact, and priority for advancing Diversity, Equity, and Inclusion (DEI) efforts to elevate underrepresented populations to leadership positions in CTSAs and their broader institutions. A thematic analysis of chat and polling data identified challenges and opportunities to achieve DEI goals, with the three most promising recommendations as: cross-institutional Principal Investigator (P.I.) action-learning workgroups, transparent policies for recruiting and promoting underrepresented minorities (URM) leadership, and a clear succession plan to nurture and elevate URM leaders. Suggestions are made to improve DEI in CTSA leadership and allow for greater representation in the translational science field.
Attacks on Health Care Workers in Historical Pandemics and COVID-19
Authors: van Stekelenburg Brett C. A. , De Cauwer Harald , Barten Dennis G. , Mortelmans Luc J. 
Published: December 2022

Abstract
Previous pandemics have been (mis)used for (geo)political reasons, for terrorism purposes, and in times of conflict. Coronavirus disease (COVID-19) has been no exception with populist politicians challenging the relations with China, calling it the “Chinese virus,” certain state actors setting up cyberterrorist actions against health care organizations in the United States and Europe, and a reported increase of violent acts against health care workers.
Aside from state-driven factors, both left- and right-wing activists and anti-vaccination activists adhering to conspiracy theories are a threat for health care organizations. Furthermore, socioeconomic, religious, and cultural factors play a role in why health care is a possible target of violence. Fear of viral pathogens, fury about financial losses due to the pandemic and governmental measures such as lockdowns, anger because of mandatory quarantines, and the disruption of burial rituals are among the reasons for people to revolt against health care providers.
Here, we provide a narrative review of the impact of violence against health care workers during the COVID-19 pandemic and earlier pandemics, and suggest preventive strategies.
Association of urinary phytoestrogens with hormone-related cancers and cancer biomarkers: NHANES 1999–2010
Authors: Liu Fubin , Peng Yu , Qiao Yating , Wang Peng , Si Changyu , Wang Xixuan , Zhang Ming , Song Fangfang 
Published: December 2022

AbstractPhytoestrogens may have potential effects on hormone-related cancers (HRC) and cancer biomarkers, but the findings have been inconsistent so far. Participants from the National Health and Nutrition Examination Survey 1999–2010 with information on the levels of urinary phytoestrogens, serum cancer biomarkers and cancer history were included. Sampling-weighted logistic regression models examined the association between urinary phytoestrogens concentrations (creatinine-standardised and log-transformed) and HRC, followed by stratified analyses by race/ethnicity, age and menopausal status for different gender. Correlation analyses between phytoestrogens and cancer biomarkers were performed. Of the total 8844 participants, there were 373 with HRC. We observed total isoflavone and enterodiol excretion were positively associated with HRC, especially in non-Hispanic white female subpopulations (Ptrend < 0·05). Similar association also existed in the total isoflavones and enterodiol levels with breast cancer. Whereas the highest concentration of total isoflavones was significantly linked to a reduced prevalence of HRC (OR = 0·40, 95 % CI: 0·19, 0·84) in white males and of prostate cancer (OR = 0·40, 95 % CI: 0·18, 0·86). Among twenty-four participants with HRC, urinary equol concentration was positively correlated with CA15.3. Also, an inverse correlation of total prostate-specific antigens (PSA) and positive correlation of the PSA ratio with urinary enterolactone were detected in thirteen prostate cancer patients. Our findings indicated that higher concentrations of total isoflavones and enterodiol were positively associated with HRC. Urinary certain phytoestrogen excretion may affect serum cancer biomarker levels in cancer patients. But further prospective studies are needed to provide stronger evidence.