bluuebunny/crossref_metadata_2025_split huggingface dataset:
Urbanization and Energy Equity: An Urban-rural Gap Perspective
Authors: Hua Wenyuan , Wang Lu , Fang Xingming , Luo Liangguo 
Published: August 2022

Abstract
Inequality is usually discussed in a monetary perspective, while the disparity in energy access sometimes is more severe. This paper mainly studies the impact of urbanization on urban-rural electricity consumption inequality with a modified STRIPAT model. We find that there is a long-run U-shaped relationship between urbanization and urban-rural electricity consumption inequality, and the estimated turning point arrives at the urbanization level of around 60%. We further carry out a regional heterogeneity analysis and then have two interesting findings: firstly, the colder northern region’s turning point arrives later than the south. Secondly, the baseline U-shaped relationship remains for developed eastern regions, while for the unde- veloped midwest, the relationship is not nonlinear but linearly neg- ative. As an extension, we lastly explore the mechanism underlying the U-shaped relationship, and find that the interaction of urbaniza- tion’s scale and efficiency effect determines the U-shaped relationship.
Giant switchable metallic-like conduction in 180° domain walls in tetragonal Pb(Zr,Ti)O3
Authors: Risch Felix , Tikhonov Yurii , Lukyanchuk Igor , Ionescu Adrian , Stolichnov Igor 
Published: August 2022

Abstract
Conductive domain walls in ferroelectrics offer a promising concept of nanoelectronic circuits with 2D domain-wall channels playing roles of memristors or synoptic interconnections. However, domain wall conduction remains difficult to control and pA-range currents typically measured on individual walls are too low for single-channel devices. Charged domain walls show higher conductivity, but are generally unstable and difficult to create. Here, we show highly conductive and stable channels on ubiquitous 180°-domain walls in the archetypical ferroelectric, tetragonal Pb(Zr,Ti)O3. These electrically erasable/rewritable channels show tens of nanoamperes (200-400nA/μm) at voltages ≤2V and metallic-like non thermally-activated transport properties down to 4K, as confirmed by nanoscopic mapping. The domain structure analysis and phase-field simulations reveal complex switching dynamics, in which the extraordinary conductivity in strained Pb(Zr,Ti)O3 films is explained by an interplay between ferroelastic 90°-domains and 180°-domains. This work demonstrates the potential of accessible and stable arrangements of nominally uncharged domain walls for nanoelectronics.
Genome-wide assessment of genetic variation and genetic differentiation for Gastrodia elata germplasm based on SLAF sequencing
Authors: XU Zhe , Shi Yana , Zhang Lei , Qian Huali , Chen Xiaolei , Su Jianyun , Chen Hao , Dong Jiahong , Cong kun , Ji Pengzhang 
Published: August 2022

Abstract
Gastrodia elata BI. is an important cultivated medicinal plant in China. To analyze the genetic diversity and evolutionary relationship of the germplasm resources of G. elata, specific Single nucleotide polymorphism (SNP) markers were developed. SLAF analysis was used to compare 28 samples of the same G. elata cultivar. Plants from 4 different varieties or different habitats were collected to explore intraspecific variation and to lay a foundation for resource protection. This will facilitate improved variety breeding in future. In this study, Single nucleotide polymorphism (SNP) genetic variation and differentiation of G. elata f. glauca, G. elata f. viridis, and G. elata f. elata were analyzed using Specific-Locus Amplified Fragment Sequencing (SLAF-seq). A total of 75.95M reads with an average sequencing depth of 19.32 × and a mean Q30 of 91.71% were obtained. Based on the 19,675 polymorphic SLAF tags, 60,238 SNPs were identified and a subset of 22,737 SNPs with minor allele frequency > 0.05 and integrity > 0.5 were selected. A model-based analysis divided the accessions into two groups, wild type G. elata f. glauca and G. elata f. viridis groups. Phylogenetic analysis also clustered the samples into the two major groups. G. elata has high genetic diversity. Population diversity was highest in G. elata f. elata and lowest in G. elata f. viridis. Analysis of molecular variance (AMOVA) revealed significant variations within individuals (92.23%). This study provides new insights into the genetic variation and differentiation of G. elata, which can be exploited to improve existing commercial cultivars.
Correlation of Stagnant Wetlands Depth and Their Ecological Status in the Central Tamilnadu District, Tamilnadu.
Authors: Krishnaraj Varunprasath , Mathesh Subha 
Published: August 2022

Abstract
Background

The wetland stagnation is the premise of the wetland depth (WD) but is lacking in detail. The research looks into correlation of stagnant wetland’s depth and their ecological status in the Central Tamil Nadu district (CTN) because of few studies. Seventy-five chosen stagnant wetlands are hydrologically isolated, depths were categorized into less than 5 feet, 6 to 10, and above 10 feet, surveyed by the range of methods from districts as Karur (KD), Namakkal (ND), and Tiruchirappalli district (TD). The human disturbance score (HDS) categorized as least impacted (0-33), moderately impacted (33-67), and highly impacted (67-100).The impacts of LULC changes over nine years (2010–2019) through the maximum likelihood method. Overall, wetland depth (WD) showed that 54% (less than 5 feet), 25.6% (5-10 feet) 20.2% (100 feet). District-wise, wetland degradation was the utmost in the TD, followed by ND and KD. Except In KD, the remaining district wetlands were MI category with diverse HDS. The correlation test revealed a positive relationship between WD against the alteration of the buffer zone, habitat, hydrology, and HDS. However, a negative relation between landscape alteration and wetland pollution. The impacts of LULC changes confirm that severe decline in wetlands habitat and water bodies’ area due to built-up area, cultivated land expansion and, increasing population. Our study supported that the WD is associated with quantified impact on wetlands conditions, but further research will need due to limited surveyed wetlands with similar geographical locations.
Impact of Pilot Zones for Green Finance Reform and Innovations on Green Technology Innovations: Evidence from Chinese Manufacturing Corporates
Authors: Sun Xinyu , Zhang Aili , Zhu Mengze 
Published: August 2022

Abstract
Green technology innovation is a crucial factor in the global quest for sustainability. In 2017, China approved the establishment of pilot zones for green financial reform and innovations to build and improve the green financial system. Using a Difference-in-Difference (DID) model, this paper examines the impact of this pilot policy on corporate green technology innovation and its transmission mechanism based on the data of green patents of Chinese A-share listed manufacturing companies between 2014 and 2019. It finds that pilot zones for green financial reform and innovations have contributed to the growth of green technology innovations. This conclusion was confirmed after a series of robustness tests. The pilot policy’s promotion of green technology innovations is mainly reflected in the application of corporate green invention patents. However, it is more significant for non-heavy polluting enterprises, high-tech certified enterprises and large enterprises. The paper also finds that the pilot policy promotes corporate green technology innovation by promoting social financing, talent support and government financial support.
On-demand and Fast Recyclable Bio-epoxy
Authors: Hong Young Gi , Jeong Jisu , Oh Dongki , Kim Minkook , Lee Min Wook , Goh Munju 
Published: August 2022

Abstract

Thermoset applications that require high mechanical and chemical stability during service life, such as windmill blades and airplanes, do not allow for biodegradability that degrades naturally over time. In this study, we developed an eco-friendly epoxy resin that maintains high chemical and mechanical stability in normal times but can be chemically decomposed under certain conditions when we want. The new bio-based EP was prepared from vanillin and raspberry ketone via an L-proline-catalyzed aldol condensation reaction. The bio-based EP exhibited excellent tensile strength (58 MPa), flexural strength (183 MPa). In addition, CFRP prepared by using synthesized EP exhibited excellent tensile strength (957 MPa), Young’s modulus (77 GPa), and interlaminar shear strength (49 MPa). Very interestingly, the synthesized EP and CFRP applicants were very rapidly degraded only under specific conditions. Therefore, this study is expected to give a great insight into solving the problems of eco-friendliness and recycling of thermoset resin applications.
Shielding effect enables ultrafast ion transfer through nanoporous membrane for highly energy-efficient electrodialysis
Authors: Lin Jiuyang , Ye Wenyuan , Xie Shuangling , Du Jiale , Liu Riri , Zou Dong , Chen Xiangyu , Yu Zijian , Fang Shengqiong , Ang Elisa Yun Mei , Toh William , Han Dan Dan , Ng Teng Yong , Seo Dong Han , Zhao Shuaifei , Bruggen Bart Van der , Xie Ming , Lee Young Moo 
Published: August 2022

Abstract
A key to sustainable management of hypersaline organic-rich wastewaters is to precisely fractionate organic components and inorganic salts (NaCl) as individual resources. Conventional nanofiltration and electrodialysis processes suffer from membrane fouling and compromise the fractionation efficacy. Here, we develop a thin-film composite nanoporous membrane (NPM) via co-deposition of dopamine and polyethyleneimine as a highly anion-conducting membrane (ACM). Experimental results and molecular dynamics simulations show that co-deposition of dopamine and polyethyleneimine effectively tailors the membrane surface properties, intensifying the charge shielding effect and enabling ultrafast anion transfer for highly efficient electrodialysis. The resulting NPM exhibits unprecedented electrodialytic fractionation of organics and NaCl (> 99.3% desalination efficiency; >99.1% organics recovery) with negligible membrane fouling, dramatically outperforming state-of-the-art anion exchange membranes. Our study sheds light on facile design of high-performance ACMs and associated new mass transport mechanisms in electrodialytic separation, paving the way for sustainable management of complex waste streams.
Analysis of differences in lymphocyte subsets and CD4+ T cells immune activation between re-detectable positive and non-re-detectable positive COVID-19 convalescent patients
Authors: Huang Zhimin , Li Guilian , Yang Zhengrong , Zhou Lin , Jiang Min , Li Hao , Zhong Yifan , Jiang Yixiang , Wang Xiaohui , He Taiping 
Published: August 2022

AbstractBackground:Recently many literature were reported on the re-detectable positive phenomenon of COVID-19 patients during recovery, but there were few studies on the lymphocyte subsets and T-lymphocyte activation indicators between the RP (re-detectable positive) and NRP (non-re-detectable positive) patients. The aim of this study was to analyze immunological characteristics of RP and NRP patients among convalescent patients from post-discharge COVID-19 patients.Methods:Anticoagulated whole blood samples were collected from 11HCs (healthy controls) and 66 COVID-19 convalescent patients, then the percentage of lymphocyte subsets and CD4+CD38+/HLA-DR+ T cells were tested with flow cytometry, SARS-CoV-2 S RBD-IgG antibody ( anti-spike protein receptor-binding domain IgG antibody) was detected by chemiluminescence.Results:B cells (%) in RP group was significantly lower than that in HC group (P=0.005), and B cells (%) decreased successively in HC, NRP and RP group, with significant differences among the three groups (P=0.016). CD3+ and CD8+T cells (%) in RP group were noticeably higher than that in NRP group (P=0.004,0.019, respectively), but there was no difference in CD4+T cells (%) and NK cells (%) among the three groups. The CD4+CD38+ and CD4+HLA-DR+T cells (%) in RP group were noticeably higher than that in HC group (P=0.025,0.018). ANOVA (Analysis of variance) of the three groups showed that CD4+CD38+ and HLA-DR+T cells (%) were also significant difference (P=0.037, 0.029), and CD4+HLA-DR+T cells (%) in the three groups increased in turn. Meanwhile, there was a substantial positive correlation between RBD-IgG titer and CD4+HLA-DR+(%) (P=0.003,r=0.517), and the RBD-IgG titer of HLA-DR+ highgroup was obviously higher than that of HLA-DR+ Lowgroup (P=0.005).Conclusions:In this work, we analyzed the immunological characteristics of re-detectable positive COVID-19 convalescent patients through lymphocyte subsets, suggesting that the low B cells (%) and the increased CD4+HLA-DR+T cells (%) in the convalescent patients of COVID-19 may be related to re-detectable positive phenomenon.
Optimization and design of fractional-order PID controller based on an improved sparrow search algorithm
Authors: Cu Wenkai , Fang Jiabin , Yuan Qing , Wei Jinjia , Yang Guidong , Zhou Zhi 
Published: August 2022

Abstract
Compared with the classical integer-order PID controller, fractional-order [[EQUATION]] (FOPID) controller is more difficult to adjust due to the introduction of two additional parameters. Aiming at the problem, a novel improved sparrow search algorithm, abbreviated as IMSSA, is proposed to perform the selection of optimal parameters for the FOPID controller. The algorithm, integrating strategies of adaptive exponential weighting factor and the stochastic mutation, enhances the searching efficiency and convergence performance of the sparrow search algorithm (SSA). The results carried on 12 benchmark functions show that the IMSSA has excellent performance in terms of convergence speed, accuracy and robustness compared with other popular algorithms, proving the effectiveness of the improved strategies. Finally, the feasibility of the IMSSA algorithm for parameter tuning of the FOPID controller is further verified by two simulation cases. The IMSSA proposed in this paper offers a novel approach to apply intelligent algorithms to solve fractional-order control problems.
Fine mapping and gene silencing pinpoint Capana10g002229 as a strong candidate gene regulating the deciduous character of ripe pepper fruit (Capsicum spp.)
Authors: Hu Fang , Dong Jichi , Zhang Shaobin , Song Zhao , Guan Wendong , Yuan Fanchong , Zhong Jian , Liu Jia , Hu Kailin , Cheng Jiaowen 
Published: August 2022

Abstract
The deciduous character of ripe fruit, which is controlled by the dominant S locus, is a domesticated trait with potential value in the pepper processing industry (Capsicum spp.). However, the gene associated with the S locus has not been identified. Here, one major QTL designated S10.1 was detected by using the F2 population (n=155) derived from BA3 (C. annuum)×YNXML (C. frutescens) and was further verified in an intraspecific backcross population (n=254) derived from the cross between BB3 (C. annuum) and its wild relative Chiltepin (C. annuum var. glabriusculum) with BB3 as the recurrent parent. Then, a large BC1F2 population derived from the self-pollination of BB3×(BB3×Chiltepin) plants and comprising 4,217 individuals was used to screen the recombinants, and the S locus was ultimately delimited into a 38.03 kb region on chromosome P10 harbouring four annotated genes. Capana10g002229, encoding a polygalacturonase (PG), was proposed as the best candidate gene for S based on sequence comparison and expression pattern analyses. Downregulation of Capana10g002229 in fruits through VIGS significantly delayed fruit softening and abscission from the fruit-receptacle junction. Taken together, the results show that Capana10g002229 could be regarded as a strong candidate gene associated with the S locus in pepper. These findings not only lay a foundation for deciphering the molecular mechanisms underlying pepper domestication but also provide a strategy for genetic improvement of the deciduous character of ripe fruit using a marker-assisted selection approach.
Aberrant cerebellar-cerebral functional connectivity in patients with obsessive-compulsive disorder, and its trajectory after pharmacotherapy and potential for diagnosis and prediction of early treatment effects
Authors: Guo Wenbin , Yan Haohao , Shan Xiaoxiao , Li Huabing , Liu Feng , Xie Guojun , Li P 
Published: August 2022

Abstract
The trajectory of abnormal cerebellar-cerebral functional connectivity (FC) in patients with obsessive-compulsive disorder (OCD) after pharmacotherapy and the association between alterations in the cerebellar-cerebral FC and changes in the clinical features of patients with OCD, as well as the possibility of building models for diagnosis and prediction of early treatment effects of OCD were unclear. We performed a longitudinal study involving 37 patients with OCD and 37 healthy controls (HCs). Patients with OCD received a 5-week treatment with paroxetine. Resting-state functional magnetic resonance imaging, seed-based FC analyses, support vector machine (SVM), support vector regression (SVR), and correlation analyses were applied to acquire and analyze the imaging and clinical data. Compared with HCs, patients with OCD showed decreased cerebellar-cerebral FC in the executive, affective-limbic, and sensorimotor networks. After treatment, patients showed significant clinical improvement and a part of the decreased cerebellar-cerebral FCs were restored. Negative correlations between abnormal cerebellar-cerebral FC at baseline and severity of compulsions, and impairment of social function were observed. Alterations in the cerebellar-cerebral FC were correlated with changes in cognition. Abnormal cerebellar-cerebral FC at baseline could serve as potential neuroimaging biomarkers for diagnosis of OCD and prediction of early treatment effects. These findings suggested that cerebellar-cerebral FC had an important role in the neuropsychological mechanisms underlying OCD and the pharmacological mechanism underlying the treatment for OCD. It was possible to develop precision medicine to identify individuals with OCD and which patients would maximally benefit from pharmacotherapy through SVM and SVR which were based on cerebellar-cerebral FC.
Exogenous melatonin alleviates neuropathic pain-induced affective disorders by suppressing NF-ᴋB/ NLRP3 pathway and apoptosis
Authors: Mokhtari Tahmineh , Yue Lu-Peng , Hu Li 
Published: August 2022

Abstract
In this study, we aimed to evaluate the anti-inflammatory and anti-apoptotic effects of melatonin (MLT) on NP-induced emotional disturbances (i.e., anxiety and depression) in a rat brain. Adult male rats were separated into three groups of sham, chronic constrictive injury (CCI): nerve ligation received the vehicle, and CCI + MLT: received MLT (10 mg/kg). Next, we used behavioral tests to evaluate pain severity, anxiety, and depression. Finally, rats were scarified for molecular and histopathological studies. Behavioral tests showed that NP could induce depression-and anxiety-like behaviors. NP activated NF-ᴋB/NLRP3 inflammasome pathways by upregulating NF-ᴋB, NLRP3, ASC, and active Caspase-1 and enhancing the concentrations of cytokines (IL1β and IL-18) in the prefrontal cortex (PFC) and hippocampus (HC). NP upregulated Bax, downregulated Bcl2, and increased cell apoptosis in the HC and PFC. The rats treated with MLT eliminated the effects of NP, as the reduced pain severity, improved anxiety- and depressive-like behaviors, ameliorated NF-ᴋB/NLRP3 inflammasome pathways, and modulated levels of cytokines in the HC and PFC had indicated this result. MLT could promote cell survival from apoptosis by modulating Bax and Bcl2. Therefore, it might be inferred that its anti-inflammatory and anti-apoptotic properties mediate the beneficial effects of MLT in NP-induced affective disorders.
Can parasitism by Tamarixia radiata (Hymenoptera: Eulophidae) affect the movement and oviposition behavior of Diaphorina citri (Hemiptera: Psyllidae)?
Authors: Oliveira Juliana S. , Reigada Carolina , Diniz Alexandre J.F , Lara Idemauro A.R. , Moral Rafael A. , Parra José R.P. 
Published: August 2022

Abstract
Diaphorina citri is the vector of the bacteria that cause HLB. The psyllid acquires the pathogen after feeding on infected plants and transmits it to other trees as it moves through the grove. The psyllid’s movement is directly affected by abiotic and biotic factors, such as the presence of conspecific insects and natural enemies. This study evaluated the effects of the presence of conspecific nymphs either not parasitized or parasitized by Tamarixia radiata on the movement and oviposition of adult female D. citri. D. citri females were released into cages containing a row of four equidistant Murraya paniculata plants. The first plant, the release point, had one of three conditions: no nymphs; non-parasitized nymphs (high and low densities); or previously parasitized nymphs. At 24, 48, and 72 h following release, the females on each plant in the cage were counted. At the end of the observations (72 h), the females were removed, and the eggs laid on the plants were counted. Discrete data analysis showed that in the presence of a high density of non-parasitized nymphs, adult psyllids were more homogeneously distributed among the plants. However, the highest oviposition rates were observed on plants without nymphs. On the other hand, in the presence of nymphs, the largest number of females remained at the release site and more eggs were deposited on plants with parasitized nymphs. This information will help to improve psyllid management techniques and releases of their natural enemy, according to their distribution in the grove.
Outcomes in Critically Ill HIV-infected patients between 1997 and 2020: analysis of the OUTCOMEREA multicenter cohort
Authors: Gaillet Antoine , Azoulay Elie , de Montmollin Etienne , Garrouste-Orgeas Maité , Cohen Yves , Dupuis Claire , Schwebel Carole , Reignier Jean , Siami Shidasp , Argaud Laurent , Adrie Christophe , Mourvillier Bruno , Ruckly Stéphane , Forel Jean-Marie , Timsit Jean-Francois 
Published: August 2022

Abstract
Background: Despite antiviral therapy (ART), 800,000 deaths still occur yearly and globally due to HIV infection. In parallel with the good virological control and the aging of this population, multiple comorbidities (HIV-associated-non-AIDS (HANA) conditions) may now be observed.Methods: Prospective, multicenter cohort, including HIV adult patients hospitalized in intensive care unit (ICU) over a 24-year period.Results: Of the 24,298 stays registered, 630 (2.6%) were a first ICU stay for HIV patients. Over time, the mean age and comorbidities level (diabetes, renal and respiratory history, solid neoplasia) of patients increased. The proportion of HIV diagnosed on ICU admission decreased significantly, while the median duration of HIV disease as well as the percentage of ART-treated patients increased. The distribution of main reasons for admission remained stable over time (acute respiratory distress > shock > coma). We observed a significant drop in the rate of active opportunistic infection on admission, while the rate of active hemopathy qualifying for AIDS increased -non significantly- with a significant increase in the anti-cancer chemotherapy administration in ICU. Admissions for HANA or non-HIV reasons were stable over time. In multivariate analysis, predictors of 60-day mortality were advanced age, chronic liver disease, past chemotherapy, SOFA score >4 at admission, hospitalization duration before ICU admission >24h, AIDS status, but not the period of admission.Conclusion: Whereas the profile of ICU-admitted HIV patients has evolved over time (HIV better controlled but more associated comorbidities), mortality risk factors remain stable, including AIDS status.