bluuebunny/crossref_metadata_2025_split huggingface dataset:
ÇAĞDAŞ TÜRK OYUN YAZARLIĞINDA BİR DIŞLAMA PRATİĞİ OLARAK HOMOFOBİ
Authors: UZUNDEMİR Ezgi , BELKIS Özlem 
Published: June 2022

1960’larda Weinberg tarafından tanımlanan homofobi terimi psikoloji, sosyoloji ve hukuk alanlarında
irdelenen bir meseledir. Günümüzde cinsiyete dayalı ayrımcılığın bir dışlama pratiği olarak tanımlanan
homofobi, etkileri ve sonuçlarıyla farklı alanlarda incelendiği gibi tiyatro alanında da işlenmiş, bu bağlamdaki
deneyimler, sonuçlar, ezilme ve dışlama pratikleri sahneye getirilmiştir. Avrupa ve Amerika tiyatrosunda
homofobiyi ele alan oyunların izleri 1930’larda görülmeye başlar, ancak homofobiyi çarpıcı şekilde işleyen
metinler için 1960’ları beklemek gerekir. Türk oyun yazarlığında ise homofobiyi işleyen oyunlara rastlamak
ancak 2000 sonrasında mümkündür. Peki 2000 sonrası Türk tiyatrosunda homofobik tutum ve davranışlar
hangi bağlamlarda nasıl işlenmiştir? Bu metinlerde homofobiye ilişkin tahakküm ve direnme pratikleri
nelerdir? Çalışmamızın amacı bu soruları yanıtlayarak 2000 sonrası Türk oyun yazarlığında cinsiyete
dayalı ayrımcılık ve homofobi temasının nasıl işlendiğini örneklerle sunmaktır. 2000 sonrasında yazılmış
oyunlardan homofobiyi ele alma, sahnelenme ve yayınlanma kriterleri gözetilerek 12 oyun seçilmiştir.
Oyunlar homofobinin teorik zemini bağlamında incelenmiş, konunun ele alınışı açısından Bireyin Kendisini
Dışlaması, Heteronormativiteden Doğan Sosyal Dışlama ve Kamusal Alanlardan Dışlama şeklinde üç
başlıkta kategorize edilebileceği görülmüştür. Sonuçta oyun yazarlarının homofobiyi aşılması gereken bir
dışlama biçimi olarak gördükleri; bazı oyunlarda direnme stratejisi üretilirken, bazılarında kabullenici bir
tutum sergilendiği görülmüştür. Direnme üreten yazarlardan bazılarının, homofobiyi komedi aracılığıyla,
bazılarının ise trajik öğelerle aşmaya çalıştığı görülmüştür.
Analysis The Effect of Problem Based Approaches and Media Experiment on Learning Interest and Critical Thinking Using Structural Equation Modeling
Authors: Sari Devita , Bektiarso Singgih , Lesmono Albertus Djoko 
Published: June 2022

The 21st-century national education paradigm requires students to have new abilities, such as critical thinking ability. However, students' critical thinking skills are still low. Likewise, interest in studying physics is still low. Physics is often considered a difficult subject, discouraging interest in studying physics. This study aims to examine the effect of a problem-based approach and experimental media on the interest in learning physics and the critical thinking skills of class XI high school students using SEM analysis. This research was conducted at senior high school on 4 Jember. The research data were collected using a questionnaire tested for validity and reliability. Furthermore, the data were analyzed using SEM analysis, developing a theoretical model, developing a flow chart, and evaluating the goodness of fit criteria. The results obtained, the problem-based approach has a significant effect on the interest in learning physics, the media for the experimental tool has a significant effect on the interest in learning physics, the problem-based approach has a significant effect on students' critical thinking skills, and the media for the experimental tool has a significant effect on the critical thinking skills of grade XI high school students. In addition, it was found that the interest in learning physics was able to mediate the effect of a problem-based approach on critical thinking skills and the influence of experimental media on critical thinking skills. So we can conclude that each dependent variable and the independent variable influence each other significantly.
LEARNING TO PREVENT AND BREAK THE CHAIN OF TRANSMISSION OF COVID-19 BY VACCINATE WOMEN, PREGNANT AND BREASTFEEDING MOTHERS THROUGH THE WEBINAR
Authors: Bachnas Muhammad Adrianes , Anggraini Nutria Widya purna , Sulistyowati Sri , Yuliantara Eric Edwin , Prabowo Wisnu , Nugraha Gagah B Adi , Firmansyah Aldi , Prameilita Dympna 
Published: June 2022

<p><strong>Background</strong>: The incidence of Covid-19 in women, pregnant, and breastfeeding mothers is still high. Currently, the government is trying to prevent and break the chain of Covid-19 transmission by vaccination. However, knowledge about Covid-19 vaccination is still limited. Therefore, Indonesian Obstetrics and Gynecology Association/<em>Perkumpulan Obstetri dan Ginekologi Indonesia</em> (POGI) members, as the spearhead of women's health, play an essential role in breaking the chain of transmission by providing knowledge about Covid-19 vaccination.</p><p><strong>Methods</strong>: All member of POGI and Youth POGI in Surakarta was educated by online method via the webinar zoom application. The level of knowledge was evaluated pre and post-webinar by using a questionnaire to see the significance.</p><p><strong>Result:</strong> Analysis of 110 participants with paired t-test obtained an average pretest value of 44.82 while the average post-test value was 57.45, with a significance value of p=0.001 (p&lt;0.05). The results of the analysis with the Chi-square test obtained p = 0.002 (p &lt;0.05) and OR = 23.40.</p><p><strong>Conclusion</strong>: There is an increased understanding of preventing and breaking the chain of transmission of Covid-19 in women, pregnant, and breastfeeding mothers by vaccinating youth POGI and POGI members after webinar and discussion, with a significance value of p=0.001 (p&lt;0.05). Webinars and discussions on preventing and breaking the chain of transmission of Covid-19 to women, pregnant, and breastfeeding mothers with vaccination by researchers provided 23.40 times better understanding than before the webinar and discussions were given.</p><p> </p><p> </p><p> </p>
Same-Day Outpatient Lower-Extremity Joint Replacement
Authors: Barra Matthew F. , Kaplan Nathan B. , Balkissoon Rishi , Drinkwater Christopher J. , Ginnetti John G. , Ricciardi Benjamin F. 
Published: June 2022

➢ The economics of transitioning total joint arthroplasty (TJA) to standalone ambulatory surgery centers (ASCs) should not be capitalized on at the expense of patient safety in the absence of established superior patient outcomes.
➢ Proper patient selection is essential to maximizing safety and avoiding complications resulting in readmission.
➢ Ambulatory TJA programs should focus on reducing complications frequently associated with delays in discharge.
➢ The transition from hospital-based TJA to ASC-based TJA has substantial financial implications for the hospital, payer, patient, and surgeon.
Mechanism and Prevention of Rockburst in Deep Multipillar Gob-Side Entry
Authors: Pan Junfeng , Du Taotao , Gao Jiaming , Xie Fei 
Published: June 2022

Abstract
Rockburst frequently occurs in deep multipillar gob-side entry in Inner Mongolia and Shaanxi, China. A case study of the Hongqinghe coal mine was analyzed to reveal the occurrence mechanism of rockburst in deep multipillar gob-side entry through theoretical and applied research. And new control methods were put forward. The results show that there is an essential difference between the surrounding rock load characteristics of multipillar gob-side entry and single-pillar gob-side entry. Within the influence area of the lateral goaf, more coal pillars will promote stress concentration, and the high stress concentration area will migrate to the coal pillar of mining roadway. The hanging roof of the working face can cause the stress concentration in the area of leading coal pillar to reach 5 times. The multipillar gob-side entry is less affected by the dynamic load of the roof of the lateral goaf. The ‘F-shaped and L-shaped’ stress source structure model of the deep gob-side multipillar entry was established, and the occurrence mechanism of rockburst is revealed. On the one hand, the static load of rockburst start foundation is formed under the superposition of lateral goaf, rear goaf, and multicoal pillar. On the other hand, the superposition of the foundation static load and the opportune static load induces the start of rockburst. Aiming at the two types of load sources, the fracturing method of kilometer bedding drilling in the roof of coal pillar area is proposed to reduce the foundation static load. The treatment method of periodic tendency blasting fracture of leading roadway roof in a working face reduces opportune static load. The field test has been carried out, and the effect was good.
An Investigation into the Mathematical and Physical Origins of the Fine-Structure Constant
Authors: Williams Lamont 
Published: June 2022

Abstract
The fine-structure constant, α, unites fundamental aspects of electromagnetism, relativity, and quantum physics. As such, it is one of the most important constants in nature. However, why it has the value of approximately 1/137 has been a mystery since it was first identified more than 100 years ago. This study explores the possibility that the value of α is linked to the spacetime geometry of the electromagnetic field between two elementary charges, connecting the smooth manifold responsible for gravity with the discreteness of the electromagnetic field. In a step-by-step manner, the study presents a logical basis for the establishment of a particular equation for α, connecting concepts from general relativity and the Standard Model, and data from experiments to measure the value of elementary electric charge. It is shown how the equation and the model upon which it is built can help explain the Landau pole in such a way that avoids the substantial problem the pole creates in quantum electrodynamics.
Investigating a Self-Management Strategy for Symptoms of Attention-Deficit Hyperactive Disorder and Drug Use.
Authors: Connolly Ross D. , Hesson Jacqueline 
Published: June 2022

Abstract
Introduction: The purpose of the present research was to examine the mediating effect that self-management has on the relationships between ADHD symptoms and nicotine dependence,alcohol use, and drug use among an undergraduate student population.Method: Data were drawn from undergraduate psychology students (N=141). We tested self-management as a mediator between (1) ADHD symptoms and nicotine use, (2) ADHD symptoms and alcohol use, and (3) ADHD symptoms and drug use.Results: Self-management was a significant mediator between ADHD symptoms and drug use, but not nicotine dependence or alcohol use.Conclusion: Self-management was a significant mediator between ADHD symptoms and drug use, which suggests that self-management may play a role in the relationship between ADHD symptoms and drug use. Individuals who have symptoms associated withADHD and who also have high levels of self-management are less likely to use drugs.
Circulating levels of PCSK9, ANGPTL3 and Lp(a) in stage III breast cancers
Authors: Chong Emilie Wong , Joncas France-Hélène , Seidah Nabil G. , Calon Frédéric , Diorio Caroline , Gangloff Anne 
Published: June 2022

Abstract
Background/ Synopsis:Cholesterol plays an important role in sustaining tumor growth and metastasis in a large variety of cancers. New and powerful cholesterol-lowering drugs are being used in combination to treat cardiovascular diseases. Thus, it becomes intuitive to verify whether these drugs could be combined to induce a cholesterol shortage sufficient to impede tumor progression. Circulating levels of the targets of a new generation of lipid-lowering drugs have not been fully investigated in cancers. Given that drugs directed against PCSK9 (evolocumab, alirocumab, inclisiran), ANGPTL3 (evinacumab) and Lp(a) (pelacarsen) are available, it becomes important to assess circulating levels of these drug targets and their role in cancers. Objective/Purpose: To compare circulating levels of PCSK9, ANGPTL3, and Lp(a) in women with stage III breast cancer versus women with premalignant or benign breast lesions. Methods: Twenty-three plasma samples from women diagnosed with a stage III breast cancer (ductal, lobular or mixed) were matched for age with twenty-three plasma samples from women bearing premalignant (stage 0, n = 9) or benign (n = 14) breast lesions. The lipid profile (Apo B, total cholesterol, HDL cholesterol and triglycerides levels) and Lp(a) were measured on a Roche Modular analytical platform, whereas LDL levels were calculated with the Friedewald formula. ANGPTL3 and PCSK9 plasma levels were quantitated by ELISA. All statistical analyses were performed using SAS software version 9.4. Results: PCSK9 levels were significantly higher in women with stage III breast cancer compared to age-matched counterparts presenting a benign lesion (95.9 +/- 27.1 ng/mL vs. 78.5 +/- 19.3 ng/mL, p < 0.05, n = 14). Moreover, PCSK9 levels positively correlated with breast disease severity (benign, stage 0, stage III) (Rho = 0.34, p < 0.05, n = 46). In contrast, ANGPTL3 and Lp(a) plasma levels did not display any association with breast disease status and lipids did not correlate with disease severity. Conclusion: In this cohort of 46 women, PCSK9 levels increased along with the severity of breast disease. Given that PCSK9 plays an important role in maintaining cholesterolemia and has been shown to degrade MHC-I on tumor cells, impeding immune T-cells response to tumors, the association between PCSK9 levels and breast disease severity needs to be further investigated in larger studies.
Effect of probiotics on growth performance, immune function, serum indices and intestinal flora of broilers
Authors: Zhao Shuo , Zhang Ning , Lu Bingxia , He Ying , Liang Jiaxing , Zhou Yingning , Xu Xinting , Quan Chenyu , Duan Qunpeng , Li Bin , Jiang Dongfu , Qin Yibin , Lu Jingzhuan , Chen Zhongwei , Zhao Wu 
Published: June 2022

Abstract
To exploring the effects of probiotics on growth performance, immune function, blood biochemical indicators and cecal flora of broilers, 5 native experimental probiotics (Bacillus coagulans, Lactobacillus fermentum, Bacillus subtilis, Bacillus licheniformis and Enterococcus faecalis) were isolated and purified. Broilers Fufeng and Sanhuang were divided: 5 single experimental probiotic groups, 1 mixed experimental probiotic group (Lactobacillus fermentum, Bacillus subtilis, Bacillus licheniformis, Enterococcus faecalis), commercial probiotics group and negative control group. Each group had 10 replicates of each type of broilers. The experimental probiotics were added to broiler’s diet during experimental period. The growth performance was measured on 21d, 42d and 77d while the immune function, blood biochemical indexes and cecal flora were measured on 77d. The growth performance results showed that experimental probiotics could effectively increase the FCR and BWG (P &lt;0.05); Thymus indexes (P &lt;0.05), spleen indexes and bursa indexes were increased; The levels of IgA, IgG and IL-2 were significantly increased (P &lt;0.05); The contents of total protein (P &lt;0.05) and albumin increased while the total cholesterol, triglycerides (P &lt;0.05), urea nitrogen and blood glucose (P &lt;0.05) were decreased; The population of LAB increased (P &lt;0.05) while E.coli decreased (P &lt;0.05) in caecal. These results indicated that different experimental probiotics had different degree of effects on experimental broilers, but their effects were similar. And the combination of several types of experimental probiotics had a more stable beneficial effects which indicated that the isolated experimental probiotics can be used as broiler feed additives to improve broiler s immunity and health in Guangxi.
Two targets that play a role in the immune microenvironment of breast cancer
Authors: Zhou Ya-Qing , Li Yue-Xuan , Wang Li-Ning , Zhang Qing , Wang Lu 
Published: June 2022

Abstract
Breast cancer (BRCA) is a malignancy that occurs in breast epithelium or ductal epithelium. The progression of BRCA is greatly influenced by the tumor microenvironment (TME). Studies have shown that Pachymic acid (PA) had an inhibitory effect on the proliferation and metastasis of BRCA cells and could also enhance immunity. We planned to use the methods of network pharmacology and bio-information analysis to clarify the role of this molecule in the TME of BRCA and its target. We predicted the potential targets of PA. In addition, by comparing the cancer profiles in the The Tumor Genome Atlas (TCGA) genome with normal profiles, differentially expressed genes (DEGs) were obtained. At the intersection of predicted targets and DEGs were 16 important genes. Enrichment analysis and survival analysis were performed on these genes. Two hub genes were found in combination with the RNA-seq expression and protein expression in T cell subsets by Immunohistochemical analysis. Finally, we used the GSE42568 data to construct a risk prediction model and obtained independent prognostic indicators. And we identified two PA targets that played a role in the TME, thus providing new ideas for research on BRCA.
Effect of poly(vinyl alcohol) (PVA) concentration on rheological behaviors of TEMPO-mediated oxidized cellulose nanofiber/PVA suspensions
Authors: Zhou Zhijun , Yao Yongbo , Zhang Junfeng , Shen Liangen , Xu Huawei , Liu Jie , Shentu Baoqing 
Published: June 2022

Abstract
2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidized cellulose nanofiber (TEMPO-CNF)/poly (vinyl alcohol) (PVA) suspension can be used to prepare composite. Therefore, understanding the viscoelastic property of TEMPO-CNF/PVA suspension is necessary. The analysis of the rheological dates from steady and dynamic rheology indicates that the suspension is pseudoplastic fluid with thixotropic behavior. When the concentration of PVA is in the dilute regime, the gel like behavior of the suspensions turns to liquid like state with the increasing frequency. Such behaviors are related to the entangled network among cellulose fibrils and the hydrogen bond interaction between TEMPO-CNFs and PVA. When the concentration of PVA is in semidilute and entangled regime, the suspensions show liquid character, because the viscosity of the suspensions are mainly determined by the entanglement of PVA molecules in homogeneous state. Furthermore, the TEMPO-CNF/PVA membranes were prepared by solution casting method. The Fourier transform infrared spectroscopy and atomic force microscope data proved the interaction between TEMPO-CNFs and PVA. This research reveals the importance of PVA concentration on the fluid characters of TEMPO-CNF/PVA suspensions, providing the approach to adjust the viscosity of TEMPO-CNF suspensions.
Evaluation of the climate change impact on Legedadi and Dire reservoirs using R-R-V-criteria
Authors: Alebel Surafel , Tura Amare 
Published: June 2022

Abstract
This study mainly deals with evaluation of the climate change impact on Legedadi and Dire reservoirs which is found in north-east Awash River Basin, Ethiopia. Projection of the future climate variables is done by using Max Planck Institute for Meteorology – Earth System Model (MPI-ESM). In the present study, future rainfall MPI-ESM product corrected by using BFTV (Bias factor time variance).The 1996–2016 was taken as baseline period against which comparison was made. A hydrological model, HEC-HMS was utilized to simulate Runoff in the study area. The performance of the model was assessed through calibration and validation process and resulted NSE = 0.87 and PEV = 7.5% during calibration and NSE = 0.84 and PEV = 7.85% during validation. The projected future climate variables has two future time series 2040s and 2080s, for both future time series an increasing trend evaporation from the open water surface of reservoirs when the projected average maximum and Minimum temperatures increase from the baseline period and precipitation shows a fluctuation event. Evaluation to the base and the future period average annual inflow volume shows an increase of 2.44% and decrease 0.99% at Dire reservoir and an increase of 5.15% and decrease 1.15% at Legedadi reservoir during 2040s and 2080s periods respectively.In general analysis of the reservoirs with current and future climate change output indicates that the reliability and resilience of the reservoirs is sensitive to precipitation change than change in temperature on differing dimensionless vulnerability of the reservoirs doesn’t demonstration extraordinary difference for both the change in precipitation and temperature.
RNA-seq provides novel insights into response to acute salinity stress in oriental river prawn Macrobrachium nipponense
Authors: Fan Yaoran , Feng Jianbin , Xie Nan , Ling Feiyue , Wang Zefei , Ma Keyi , Hua Xueming , Li Jiale 
Published: June 2022

Abstract
The oriental river prawn Macrobrachium nipponense is an important aquaculture species in China, Vietnam, and Japan. This species could survive in the salinity ranging from 7 to 20 ppt and accelerate growth in the salinity of 7 ppt. To identified the genes and pathways in response to acute high salinity stress, M. nipponense were exposed to the acute high salinity of 25 ppt. Total RNA from hepatopancreas, gills, and muscle tissues was isolated, and then sequenced using high throughput sequencing method. Differentially expressed genes (DGEs) were identified, and total of 632, 836, and 1246 DEGs with a cutoff of significant two-fold change were differentially expressed in hepatopancreas, gills, and muscle tissues, respectively. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genome pathway enrichment analysis were conducted. These DEGs were involved in the GO terms of cellular process, metabolic process, membrane, organelle, binding, and catalytic activity. The DEGs of hepatopancreas and gill tissues were mainly enriched in PPAR signaling pathway, longevity regulating pathway, protein digestion and absorption, and the DEGs of muscle tissue in arginine biosynthesis, adrenergic signaling in cardiomyocytes, cardiac muscle contraction, and cGMP-PKG signaling pathway. Real-time PCR conducted with fifteen selected DEGs indicated high reliability of digital analysis using RNA-Seq. This work provides a comprehensive insight into the molecular responses to high salinity stress in M. nipponense, which provide a novel contribution to understanding of the molecular mechanisms of adaptation to salinity stress in euryhaline crustaceans.