bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green Lacewing Chrysoperla rufilabris (Neuroptera: Chrysopidae) is a potential biological agent for controlling crapemyrtle bark scale (Hemiptera: Eriococcidae)
Authors: Wu Bin , Xie Runshi , Gu Mengmeng , Qin Hongmin 
Published: April 2022

AbstractCrapemyrtle bark scale (CMBS; Acanthococcus lagerstroemiae), an invasive sap-sucking hemipteran, has spread across 16 U.S. states. Infestation of CMBS negatively impacts the flowering of crapemyrtles and reduces the aesthetic quality of ornamental plants. The widespread use of soil-applied neonicotinoid insecticides to repress the CMBS infestation could threaten important beneficial insects; therefore, using natural enemies to control CMBS is greatly needed. This study evaluated larval green lacewing (Chrysoperla rufilabris) as a biocontrol agent of CMBS. Predatory behavior of the larval C. rufilabris upon CMBS was documented under a stereomicroscope using infested crapemyrtle samples collected from different locations in College Station. Predation potential of C. rufilabris upon CMBS eggs and foraging performance using Y-maze assay were both investigated in laboratory conditions. Results confirmed that larval C. rufilabris preyed on CMBS nymphs, eggs, and adult females. The evaluation of predation potential results showed that the number of CMBS eggs consumed in 24 hours by 3rd instar C. rufilabris (176.4 ±6.9) was significantly higher than by 2nd instar (151.5±6.6) and by 1st instar (11.8±1.3). The foraging performance results showed that larval C. rufilabris could target CMBS under dark, indicating that some cues associated with olfactory response were likely involved when preying on CMBS. This study is the first report that validated C. rufilabris as a natural predator of CMBS and its potential as a biological agent to control CMBS. Future investigation about the olfactory response of larval C. rufilabris to CMBS would benefit the development of environmental-friendly strategies to control CMBS spread.
The field of protein function prediction as viewed by different domain scientists
Authors: Ramola Rashika , Friedberg Iddo , Radivojac Predrag 
Published: April 2022

AbstractExperimental biologists, biocurators, and computational biologists all play a role in characterizing a protein’s function. The discovery of protein function in the laboratory by experimental scientists is the foundation of our knowledge about proteins. Experimental findings are compiled in knowledge-bases by biocurators to provide standardized, readily accessible, and computationally amenable information. Computational biologists train their methods using these data to predict protein function and guide subsequent experiments. To understand the state of affairs in this ecosystem, centered here around protein function prediction, we surveyed scientists from these three constituent communities. Our objective was to understand their views on this research area, including the importance of the problem, the usefulness of the methods, the bottlenecks in the field, and the level of interaction between the communities. We show that the three core communities have common but also idiosyncratic perspectives on the field. Most strikingly, experimentalists rarely use modern prediction software, but when presented with predictions, report many to be surprising and useful. Ontologies appear to be highly valued by biocurators, less so by experimentalists and computational biologists, yet controlled vocabularies bridge the communities and simplify the prediction task. Additionally, many software tools are not readily accessible and the predictions presented to the users can be broad and uninformative. To meet both the social and technical challenges in the field, a more productive and meaningful interaction between members of the core communities is necessary.
Localization, induction, and cellular effects of tau-phospho-threonine 217
Authors: Rajbanshi Binita , Mandell James W. , Bloom George S. 
Published: April 2022

ABSTRACTIntroductionTau phosphorylation at T217 is a promising AD biomarker, but its functional consequences were unknown.MethodsHuman brain and cultured mouse neurons were analyzed by immunoblotting and immunofluorescence for total tau, taupT217, taupT181, taupT231 and taupS396/pS404. dSTORM super resolution microscopy was used to localize taupT217 in cultured neurons. EGFP-tau was expressed in fibroblasts as wild type and T217E pseudo-phosphorylated tau, and fluorescence recovery after photobleaching (FRAP) reported tau turnover rates on microtubules.ResultsIn brain, taupT217 appears in neurons at Braak stages I-II, becomes more prevalent later and co-localizes partially with other phospho-tau epitopes. In cultured neurons taupT217, is increased by extracellular tau oligomers (xcTauOs), and is associated with developing post-synaptic sites. FRAP recovery was fastest for EGFP-tauT217E.ConclusionTaupT217 increases in brain as AD progresses and is induced by xcTauOs. Post-synaptic taupT217 suggests a role for T217 phosphorylation in synapse impairment. T217 phosphorylation reduces tau’s affinity for microtubules.
Sequence characterization of the complete chloroplast genome of Eupatorium fortunei
Authors: Yan Kan , Ran Juan , Bao Songming , Zhang Nai , Zhao Wei , Ma Yanni , Ishimwe Marie Angela 
Published: April 2022

AbstractEupatorium fortunei has been utilized as herbal medicine to cure various diseases in various regions of the world especially China, Korea, and other Asian countries. The available literature shows Eupatorium fortunei contain anti-metastatic, anti-angiogenic, anti-bacterial, and anti-oxidant, along with compounds to cure human cancer. In present study, Eupatorium fortunei was used as an experimental material, and its genome was sequenced based on high-throughput sequencing technology. We assembled the complete chloroplast genome of Eupatorium fortunei and obtained NCBI accession number (OK545755). We analyzed chloroplast genome structure of Eupatorium fortunei and systematic analysis was conducted, including the size of the entire genome sequence, genome volume, large single-copy (LSC), small single-copy (SSC), inverted repeat region (IR)-LSC/SSC boundaries, etc. The obtained results showed that chloroplast genome of Eupatorium fortunei is a typical tetrad structure with a total length of 152,401 bp and a sum of 133 annotated genes, including eight ribosomal RNA (rRNA)-encoding genes, 37 transfer RNA (tRNA)-encoding genes, 87 protein-encoding genes, and one pseudo-gene. A sum of 29 Single Sequence Repeats (SSR)s were identified for mono-nucleotide, di-nucleotide and tri-nucleotide microsatellites with mono-nucleotides in majority. The phylogenetic analysis revealed that Eupatorium fortunei is more closely related to Litothamnus nitidus and belongs to the same branch. The genome assembly and analysis of the chloroplast genome of Eupatorium fortunei provides more accurate evidence for further taxonomic identification and localization of Asteraceae/Compositae plant.
Fleeting Effects of Incentives: Adult Age Differences in ERP Measures of Motivated Attention
Authors: Sullivan Margot D. , Kudus Farrah , Dyson Benjamin J. , Spaniol Julia 
Published: April 2022

AbstractReward-based motivation is associated with transient and sustained dopaminergic activity and with modulatory effects on attention and cognitive control. Age-related changes in the dopamine system are well documented, but little is known about age differences in the temporal dynamics of motivational influences on cognitive functions. The current study examined the effects of financial incentives on visual attention using event-related potentials (ERPs). Participants (26 younger, aged 18-33; 24 older, aged 65-95) completed an incentivized flanker task in which trial-level incentive cues signaled the availability of performance-contingent reward, and subsequent alerting cues signaled the onset of the flanker target. ERP components of interest included incentive-cue P2 and CNV, alerting-cue N1, target N1, and target P3. Transient effects of incentives were assessed by comparing ERP amplitudes across incentive and non-incentive trials from mixed-incentive blocks. Younger adults showed transient effects of incentives on all components, whereas older adults showed effects for incentive-cue P2 and alerting-cue N1 only. Sustained effects of incentives were assessed by comparing ERP amplitudes across non-incentive trials from mixed-incentive blocks and non-incentive trials from pure non-incentive blocks. Both age groups showed sustained effects of incentives on cue-locked ERPs, but only younger adults showed sustained effects on target-locked ERPs. Reaction-time patterns mirrored the ERP findings, in that younger adults showed greater incentive-based modulation than older adults. Overall, these findings suggest that both transient and sustained effects of incentives on visual attention are more fleeting for older than younger adults, consistent with widespread alterations in dopaminergic neuromodulation in aging.
genomeSidekick: a user-friendly epigenomics data analysis tool
Authors: Chen Junjie , Zhu Ashley J. , Packard René R. Sevag , Vondriska Thomas M. , Chapski Douglas J. 
Published: April 2022

AbstractRecent advances in epigenomics measurements have resulted in a preponderance of genomic sequencing datasets that require focused analyses to discover mechanisms governing biological processes. In addition, multiple epigenomics experiments are typically performed within the same study, thereby increasing the complexity and difficulty of making meaningful inferences from large datasets. One gap in the sequencing data analysis pipeline is the availability of tools to efficiently browse genomic data for scientists that do not have bioinformatics training. To bridge this gap, we developed genomeSidekick, a graphical user interface written in R that allows researchers to perform bespoke analyses on their transcriptomic and chromatin accessibility or chromatin immunoprecipitation data without the need for command line tools. Importantly, genomeSidekick outputs lists of up- and downregulated genes or chromatin features with differential accessibility or occupancy; visualizes ‘omics data using interactive volcano plots; performs Gene Ontology analyses locally; and queries PubMed for selected gene candidates for further evaluation. Outputs can be saved using the user interface and the code underlying genomeSidekick can be edited for custom analyses. In summary, genomeSidekick brings wet lab scientists and bioinformaticians into a shared fluency with the end goal of driving mechanistic discovery.
Phylogeny and Metadata Network Database for Epidemiologic Surveillance
Authors: Stott Garrick , Lyu Leke , Veytsel Gabriella , Kuo Jacky , Lewis Ryan , Brown Armand , Fujimoto Kayo , Bahl Justin 
Published: April 2022

AbstractThe ongoing SARS-CoV-2 pandemic has highlighted the difficulty in integrating disparate data sources for epidemiologic surveillance. To address this challenge, we have created a graph database to integrate phylogenetic trees, associated metadata, and community surveillance data for phylodynamic inference. As an example use case, we divided 22,713 SARS-CoV-2 samples into 5 groups, generated maximum likelihood trees, and inferred a potential transmission network from a forest of minimum spanning trees built on patristic distances between samples. We then used Cytoscape to visualize the resultant graphs.
Key components of successful post–hurricane reconstruction of transportation infrastructures
Authors: Safapour Elnaz , Kermanshachi Sharareh , Rouhanizadeh Behzad 
Published: April 2022

PurposeIn the aftermath of hurricanes, the damage levied on transportation infrastructures increases the timeliness of emergency responses and recovery procedures, making it essential that they are reconstructed as quickly as possible – on time and within budget. The aim of this study was to determine significant performance indicators (PIs) that considerably affect cost and schedule performance as well as reworks in post–hurricane reconstruction of transportation infrastructure including highways, bridges, roadways, etc. Additionally, the determined PIs were clustered to investigate key components.Design/methodology/approachThe root causes of reconstruction projects' poor performance were identified through the existing literature, and 30 transportation infrastructure case studies were analyzed to determine the significant PIs that corresponded to cost, schedule performance and reworks. The factor analysis method was used to cluster the significant PIs and determine the key components affecting them.FindingsEight key components were found for cost, eight for schedule performance and six for reworks. The key components of cost performance are shortage of resources, information management, coordination, safety, location, quality of materials, quality of resources and project complexity. The key components of reconstruction schedule performance are human resources, risk management, work suspension, material resources, productivity, on-site inspections, geometrical characteristics and level of reconstruction complexity. The six key components of reconstruction reworks are logistic management, pace of decision-making, accommodation for staff, environmental issues, available temporary paths and volume of debris.Originality/valueThe outcomes of this research will assist authorities and decision makers in identifying and evaluating the critical root causes of poor cost performance, poor schedule performance and reworks and will enable them to facilitate the timely and effective allocation of resources.
Integrating the extended theory of planned behavior model and the food-related routines to explain food waste behavior
Authors: Chen Mei-Fang 
Published: April 2022

PurposeThis study aimed to explore the determinants of household food waste behavior to mitigate the negative effects of consumption on climate change through a model that extends the theory of planned behavior (TPB) by integrating motivations to reduce food waste – in addition to moral norms – as well as situational factors – in addition to planning and shopping routines – that affect food waste.Design/methodology/approachOnline self-report questionnaires were used to collect empirical data in Taiwan; a total of 304 responses were retrieved. Two-step structural equation modeling was subsequently conducted.FindingsThe results indicated that the extended TPB model, which notably included motivations to reduce food waste and moral norms regarding reducing food waste, explained 56.84% of the variance in intention not to waste food. Perceived behavioral control regarding reducing food waste was associated with food planning and shopping routines. Intention not to waste food, food shopping routines, and situational factors were determinants of food waste behavior and explained 15.72% of the variance in food waste behavior.Originality/valueThe main theoretical contribution of this study is that the extended TPB model that includes both moral norms and motivation to reduce food waste elucidates the role of motivations in the formation of attitudes. In addition, not only intention not to waste food and shopping routines but also situational factors explained food waste behavior. These findings provide practical and policy implications for enhancing people's intention not to waste food and for reducing their actual food waste behavior.
Common conceptual flaws in realizing maqāṣid al-Sharīʿah vis-à-vis Islamic finance
Authors: Al-Nahari Ameen Ahmed Abdullah Qasem , Monawer Abu Talib Mohammad , Haji Abdullah Luqman Bin , Ali Abdul Karim Bin , Abdul Rahman Noor Naemah Binti , Achour Meguellati 
Published: April 2022

PurposeThis paper aims to scrutinize the misconceptions about maqāṣid al-Sharīʿah (objectives of Islamic law) that complicate its actualization, particularly in Islamic finance.Design/methodology/approachThis study adopts a qualitative inductive method to identify the flaws in understanding maqāṣid al-Sharīʿah vis-à-vis Islamic finance. It uses the views of classical and modern maqāṣid scholars to critically examine the flaws.FindingsThis study concludes that the five objectives of the Sharīʿah constitute the framework of maṣlaḥah (well-being). The levels of maṣlaḥah ― namely ḍarūriyyāt (essentials), ḥājiyyāt (needs) and taḥsīniyyāt (embellishments) ― are the categories of the means to ends. The demand for financial products falls under the ḥājiyyāt and taḥsīniyyāt categories, not ḍarūriyyāt. The maqāṣid (objectives) are derived from aḥkām (provisions) being verified by the parameters, while aḥkām are guided by maqāṣid.Research limitations/implicationsThis study recommends further research to theorize the concepts of ḍarūriyyāt, ḥājiyyāt, taḥsīniyyat and mukammilāt (complements); to harmonize the maqāṣid with their essential elements and to formulate a conceptual framework for actualizing maqāṣid al-Sharīʿah in Islamic finance.Practical implicationsThis paper will improve perceptions and bridge gaps between the understanding of maqāṣid theory and existing practices. It suggests that instead of ḍarūriyyāt, Islamic financial institutions (IFIs) should refer to ḥājiyyāt and taḥsīniyyāt.Originality/valueThis paper identifies and clarifies the misconceptions about maqāṣid al-Sharīʿah vis-à-vis Islamic finance in the existing literature. The findings align with the views of leading maqāṣid scholars in understanding the idea.
Analysis of time-varying seismic fragility of rigid frame pier of offshore bridge
Authors: Liang Yan , Wei Yingying , Li Panjie , Niu Huan , Shu Jingxiao 
Published: April 2022

PurposeAlthough mechanical behavior of rigid frame pier has been clearly recognized, their time-varying seismic performance are yet to be well characterized due to some offshore piers that are eroded by chloride ion and located in earthquake-prone area. In this study, the time-variant seismic fragility analysis was conducted to evaluate seismic performance of rigid frame pier under four damage states with considering the time-varying characteristics of the material.Design/methodology/approachThis paper establishes the nonlinear finite element model for the investigated offshore reinforcement concrete (RC) pier with considering the time-varying durability damage of the materials and defines the damage state, damage position and damaged index of the offshore RC pier. It also analyzes the time-varying seismic fragility of the offshore RC pier by using the capacity demand ratio method in the whole life cycle.FindingsThe results show that chloride induced corrosion has a significant effect on the rigid frame pier and bending capacity of top section is less than that of bottom section. The rate of decline accelerates after the service life reaching 30 years under the coupling of the earthquake and the environmental erosion. In the early years of service, the seismic fragility of the structure changed slowly.Originality/valueThis paper analyzes the influencing factors of seismic performance of rigid structure pier, and analyzes the seismic capacity and seismic performance of rigid structure pier under different service periods.
The impact of tourism promotion in tourist destinations: a bibliometric study
Authors: Florido-Benítez Lázaro 
Published: April 2022

Purpose
This paper aims to provide an assessment of tourism promotion in tourist destinations and airports (TPTDs) and to organize and classify the literature on tourism promotion, with the aim of staging the importance of this topic and encouraging future research in the projection of tourism and marketing sectors.

Design/methodology/approach
The paper uses the Social Sciences Citation Index (SSCI) database to analyze the bibliometric in TPTDs topic from 2000 to 2021. Additionally, the paper also uses the visualization of similarities (VOS) viewer software to map graphically the bibliographic material. The graphical analysis uses bibliographic coupling, co-citation, citation and co-occurrence of keywords.

Findings
This study provides an amended new definition of tourism promotion, which is the efficient management of a destination’s resources and strategic plans by destination marketing organizations (DMOs) to adapt the tourism supply to market trends and will empower tourists to visit such destinations. Furthermore, results also show a new paradigm applied to TPTDs topic and classified in five first-order research streams. Digital and mobile marketing, infrastructure, branding, quality, accessibility and information factors about a specific destination which are mostly demanded by tourists are considered as an important means of promotion for the tourism industry.

Originality/value
The contribution of this study is important to identify new challenges and opportunities for researchers, DMOs, airport and airlines operators and stakeholders, as disentangling existing contradictions and applying new theoretical framework to make better future decisions by researchers and organizations to provide higher quality to new research in the context of the TPTDs.
Revealing or concealing: privacy information disclosure in intelligent voice assistant usage- a configurational approach
Authors: Cao Gaohui , Wang Ping 
Published: April 2022

PurposeBased on communication privacy management (CPM) theory, this study aimed to explore how gender and age criteria, motivational criterion (locatability), benefit-risk ratio criteria (perceived benefits of privacy information disclosure and privacy concerns), contextual criteria (privacy experience) and boundary coordination and turbulence (perceived effectiveness of privacy policy) interact and combine in leading to voice assistant (VA) users' intention to reveal or conceal their privacy information.Design/methodology/approachA questionnaire was designed and distributed to car drivers who have intelligent VA use experience while driving. A total of 230 valid responses were collected. The fuzzy-set qualitative comparative analysis (fsQCA) approach was used to analyse the data.FindingsVia configuration analysis with fsQCA, five equivalent configurations leading to the high intention of disclosing privacy information, and one configuration leading to the intention of concealing privacy information were identified. Four theoretical configurational propositions were proposed. Moreover, the theoretical and practical implications of the findings are discussed.Originality/valueThis study offers some insightful implications in the field of private information communication in artificial intelligence applications as well as practical implications for intelligent VA application design. The findings provide empirical evidence of privacy communication management in the context of smart VA usage.