bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aminoglycoside antibiotic kanamycin functionalized tetraphenylethylene molecular probe for highly selective detection of bovine serum albumin protein
Authors: Jadhav Ratan W. , Wagalgave Sopan M. , kumbhar Bajarang V. , Khadake Rushikesh M. , Rode Ambadas B. , Bhosale Sidhanath V. , Bhosale Sheshanath V. 
Published: July 2022

AbstractA novel tetraphenylethylene (TPE) functionalized aminoglycoside antibiotic kanamycin (TPE-kana 1) has been successfully synthesized and characterized by means of modern analytical and spectroscopic techniques. The probe TPE-kana 1 showed strong affinity towards bovine serum albumin (BSA) compared to its other biological competitors. The recognition of BSA have been investigated employing UV–Vis absorption and fluorescence emission spectroscopy. The significant color change of TPE-kana 1 with BSA can be observed by necked eye, where the role of AIE-active TPE molecule is handle in both optical and colorimetric changes. The quenching of fluorescence of TPE-kana 1 with BSA was characterized by fluorescence spectroscopy, with 71.16% of quenching efficiency. Moreover, the Stern–Volmer quenching constant was calculated and found to be 2.46 × 107 M−1. Probe TPE-kana 1 showed detection limit of 2.87 nM (nM) towards BSA with binding constant 7.56 × 107 M. A molecular docking study is also performed to investigate the detail interactions between TPE-kana 1 with the sites of BSA via non-covalent i.e., H-bonding, π-cation interactions, π-donor hydrogen bonds and π-π interactions. The lowest binding energy conformation was found at − 10.42 kcal/mol.
KHSRP loss increases neuronal growth and synaptic transmission and alters memory consolidation through RNA stabilization
Authors: Olguin Sarah L. , Patel Priyanka , Buchanan Courtney N. , Dell’Orco Michela , Gardiner Amy S. , Cole Robert , Vaughn Lauren S. , Sundararajan Anitha , Mudge Joann , Allan Andrea M. , Ortinski Pavel , Brigman Jonathan L. , Twiss Jeffery L. , Perrone-Bizzozero Nora I. 
Published: July 2022

AbstractThe KH-type splicing regulatory protein (KHSRP) is an RNA-binding protein linked to decay of mRNAs with AU-rich elements. KHSRP was previously shown to destabilize Gap43 mRNA and decrease neurite growth in cultured embryonic neurons. Here, we have tested functions of KHSRP in vivo. We find upregulation of 1460 mRNAs in neocortex of adult Khsrp−/− mice, of which 527 bind to KHSRP with high specificity. These KHSRP targets are involved in pathways for neuronal morphology, axon guidance, neurotransmission and long-term memory. Khsrp−/− mice show increased axon growth and dendritic spine density in vivo. Neuronal cultures from Khsrp−/− mice show increased axon and dendrite growth and elevated KHSRP-target mRNAs, including subcellularly localized mRNAs. Furthermore, neuron-specific knockout of Khsrp confirms these are from neuron-intrinsic roles of KHSRP. Consistent with this, neurons in the hippocampus and infralimbic cortex of Khsrp−/− mice show elevations in frequency of miniature excitatory postsynaptic currents. The Khsrp−/− mice have deficits in trace conditioning and attention set-shifting tasks compared Khsrp+/+ mice, indicating impaired prefrontal- and hippocampal-dependent memory consolidation with loss of KHSRP. Overall, these results indicate that deletion of KHSRP impairs neuronal development resulting in alterations in neuronal morphology and function by changing post-transcriptional control of neuronal gene expression.
Flexible thermoelectric generator with high Seebeck coefficients made from polymer composites and heat-sink fabrics
Authors: Lin Shuping , Zhang Lisha , Zeng Wei , Shi Dongliang , Liu Su , Ding Xujiao , Yang Bao , Liu Jin , Lam Kwok-ho , Huang Baolin , Tao Xiaoming 
Published: July 2022

AbstractLight and flexible thermoelectric generators working around room temperature and within a small temperature range are much desirable for numerous applications of wearable microelectronics, internet of things, and waste heat recovery. Herein, we report a high performance flexible thermoelectric generator made of polymeric thermoelectric composites and heat sink fabrics. The thermoelectric composites comprise n- and p-type Bi2Te3 particles and poly(3,4-ethylenedioxythiophene) polystyrene sulfonate, exhibiting a synergic effect that results in Seebeck coefficients higher than those of the constituent alloys and conductive polymer. The flexible and light thermoelectric generator produces an output power of 9.0 mW, a specific output power of 2.3 mW/g, and an areal power density of 6.5 W/m2 at ΔT = 45 K. By using the heat sink fabrics to maintain a large and uniform distribution of temperature difference across the generator, a three-fold increment of the output power is obtained.
COVID-19 Resulting in Potential Hearing Damage of Rodents
Authors: Miao Jinxin , Xu Hongen , Tian Yongan , Wang Jianyao , Tang Wenxue , Wang Yaohe , Miao Mingsan , Liu Jianbo , Xue Xia , Guo Yongjun 
Published: July 2022

Abstract
Objectives To find out the association between the sensorineural hearing loss and coronavirus disease 2019 (COVID-19), the expression of ACE2 and TMPRSS2 in hamsters and mice was detected.
Design Using the public data from the National Center for Biotechnology Information and the Global Initiative on Sharing All Influenza Data, the expression of ACE2 and TMPRSS2 at the transcriptomic, DNA, and protein levels of ACE2 in the brain, inner ear, and muscle from the golden Syrian hamsters (Mesocricetus auratus) and mice (Mus musculus) was assessed.
Results We identified ACE2 and TMPRSS2 expressed at different levels in the inner ear and brain at DNA and transcriptomic levels of both mice and hamsters. The protein expression from the brain and inner ear showed a similar pattern, while the expression of ACE2 from the inner ear was relatively higher than that from the muscle.
Conclusion Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shows genetic potential to infect the hearing system of rodents and lead to sudden sensorineural hearing loss that can be used as a characteristic to detect asymptomatic patients of COVID-19.
Cerebral Aspergillosis in an Immunocompetent Patient after COVID-19 Infection
Authors: Almeida Laryssa C. Azevedo , Braga Henrique Moura , Costa Bruno Silva 
Published: July 2022

AbstractFungal brain abscesses are an uncommon condition in the immunocompetent population, especially due to the etiologic agent Aspergillus sp. The emerging coronavirus disease 2019 (COVID-19) pandemic brought about neurological manifestations that were previously little known, caused by the direct manifestations of the virus, as well as by the therapy itself, with hospitalization and use of corticosteroids. This manuscript highlights the need for attention in the management of patients with neurological disorders and history of COVID-19 infection. In the current paper, we report the case of a patient without comorbidities who presented multiple brain abscesses caused by Aspergillus fumigatus, after infection by Severe Acute Respiratory Syndrome Coronavírus 2 (SARS-CoV-2).
Assessment of oil quality traits in some important exotic and indigenous collections of
Authors: Kumari Nisha , Avtar Ram , Singh Vivek K. , Kumar Neeraj , Bishnoi Mahavir , Singh Manjeet 
Published: July 2022

Context In the breeding of oilseed Brassica crops for human consumption and animal feed, the main objective is the expansion of commercial varieties with low erucic acid, low glucosinolates, and high oleic acid content. Indian cultivars are high in erucic acid and glucosinolates. Aims This study examined variation among species and genotypes of Brassica for early screening potential in breeding programs for enhanced oil quality of rapeseed mustard. Methods Seeds of 165 Brassica genotypes including exotic and indigenous collections from India were analysed for oil content, fatty acid composition of seed oil, and glucosinolate content in seed meal. Species represented were B. juncea (159 genotypes), B. rapa (2), B. napus (2), B. carinata (1) and Eruca sativa (1). Correlation, principal component and cluster analyses were performed. Key results Substantial genetic variability was detected among genotypes for all studied traits. Oil content ranged from 32% to 45%. Oleic (11.93–54.13%), linoleic (13.33–35.85%), linolenic (3.42–20.77%) and erucic (0–50.70%) acids were the dominant fatty acids. Erucic acid had a significant and negative association with oleic, linoleic, linolenic and eicosenoic acids. Glucosinolate content varied from 7.32 to 282.17 μmol/g in the defatted meal. The first two principal components accounted for 48.10% of cumulative variation. Genotypes were grouped into five major clusters. Genotypes of one cluster had high oleic acid (46.73%) and low erucic acid (1.72%). Conclusions Five promising genotypes were found with low glucosinolate (<30 μmol/g defatted meal) and low erucic acid (<2%) content (i.e. ‘00’ characteristics). Implications The inherent variation for seed oil quality traits across assessed Brassica genotypes suggests their potential for application in future breeding operations.
Production aspects of hay of tropical pasture of
Authors: Nascimento K. S. , Edvan R. L. , Santos C. O. , Sousa J. M. S. , Nascimento R. R. , Miranda R. S. , Bezerra L. R. , Biagiotti D. , Lima Neto A. F. , Araújo M. J. 
Published: July 2022

Context Tropical pasture have been little explored for haymaking, due to lack of information regarding loss of nutrients and of forage dehydration. Aims This study aimed to evaluate the production aspects of tropical pasture hays. Methods To characterise forage dry mass yield and dehydration rate, we studied the grasses Marandú, Xaraés, Massai, Paredão, Planaltina and Tupã. The water soluble carbohydrates concentration curve, chemical composition and in situ rumen degradability of dry mass, crude protein and neutral detergent fibre were also determined. Key results The highest forage dry mass yield was observed in 2018, when Planaltina and Paredão performed best (6.28 and 5.26 ± 0.41 t of dry matter ha−1, respectively). There was no genotype × dehydration time interaction (P = 0.81) on water soluble carbohydrates. Exposure to sun resulted in a linear decreasing effect (P < 0.01) on water soluble carbohydrates content, with loss of 5.03 g kg−1 for each hour of exposure to the sun during the haymaking process. There was an interaction effect (P < 0.01) between type of material and genotype on the content of dry matter, mineral matter, crude protein and neutral detergent fibre (P < 0.01). In situ degradability of Massai grass dry mass was higher for the hay (758.0 and 253.8 ± 7.9 g kg−1 for hay and in natura material, respectively). Conclusions and implications The greater amount of leaves in relation to stem indicates that Massai grass is more efficient in dehydration during the first hours of exposure to the sun, as well as sustaining lower losses.
Apparent resistance to brodifacoum in
Authors: Sran Suman P. K. , Gartrell Brett G. , Fisher Penny , Armstrong Doug P. 
Published: July 2022

Context Anticoagulants have been used in New Zealand for decades, but few data are available on the sustainability of these toxins for rodent control. It is important to regularly monitor for resistance in long-term brodifacoum-use areas and establish a database for future references. Aims This study aimed to estimate the effective dose (ED50) of brodifacoum for ship rats from an area of New Zealand with no history of brodifacoum use, in order to establish a blood-clotting response test for assessing resistance in rodent populations from other areas. Methods A ranging study was conducted whereby successive groups of ship rats were administered brodifacoum doses that were increased or decreased progressively, until an International Normalised Ratio (INR) of 3.6 was reached. Linear regression was used to model the relationship between dose and INR, and ED50 dose was estimated using the resulting model. Results None of the rats appeared susceptible to brodifacoum at previously reported LD50 exposures for this species. The ED50 of brodifacoum was estimated to be 2.88 mg/kg for males and 3.81 mg/kg for females. These values are 6–8 times greater than the previously published lethal dose values for ship rats in New Zealand. Conclusions Blood-clotting inhibition was detected in the rats only following high doses of brodifacoum, which may indicate resistance within the sampled population. Implications Relatively low susceptibility, or resistance, to brodifacoum in New Zealand ship rats may be mediated by spatial connections between areas with different histories and patterns of anticoagulant rodenticide use.
Peat subsidence in a tropical rubber plantation during a strong El Niño year
Authors: Wakhid Nur 
Published: July 2022

Abstract
El Niño usually induces peat fires because dry season was prolonged and rainfall was low. This event potentially increases soil CO2 emissions and peat subsidence on tropical peat due to low groundwater level. Despite this, El Niño impacts on peat soil subsidence is understudied in Indonesia. To fill the gap, we measured peat surface elevation to determine peat soil subsidence at monthly basis during dry season, from June to November, in the strong El Niño year of 2015 and the normal year of 2014. A rubber plantation cultivated on peat soil was selected as a representative area for this research. Subsidence (in cm) was determined by calculating the difference in ground elevation between June and November for 2014 and 2015. Measurement was done by inserting three steel pipes vertically until underlying mineral substrate. We found that peat soil subsidence in strong El Niño year was larger than that of normal year. This finding can be further exploited as the baseline information for peatland management under climate change and or in extreme weather.
Re-wetted peatland management through selection of native species in Sinarmas Forestry
Authors: Wahno I , Nugraheni M , Herdyantara B , Gafur A , Tjahjono B 
Published: July 2022

Abstract
Sinarmas Forestry R&D has initiated studies on development of native species in peatland since 2000. This paper describes progress of the research, especially in the last 5 years, which coincided with the implementation of the Government Regulation 71 of 2014 and in collaboration with Asia Pulp and Paper (APP), Forest Research and Development Agency of KLHK, Gadjah Mada University (UGM), Deltares and Euroconsult Mott MacDonald (EMM). The main objective was to identify alternative local species apart from Acacia crassicarpa as pulp and paper raw materials in peat areas with water table of < 40 cm (rewetted areas). Series of different trials have been established, including progeny and species trials. This paper focuses on the species trials. The trials were conducted in Siak Regency, Riau, in a randomized complete block design with 5 replicates and plot size of 6 x 6 trees. Based on the survival rate and growth data, 4 native trees, i.e. Geronggang (Cratoxylon arborescens), Gelam (Melaleuca leucadendra), Balangeran (Shorea balangeran), and Bush Merah (Lophostemon suaveolens) were great potentials as alternatives to A. crassicarpa. Propagation procedures of these species, including tissue culture techniques, are currently being explored.
The performance of grain yield and variability of ten high yielding varieties of rice at tidal swampland
Authors: Saleh M , Khairullah I 
Published: July 2022

Abstract
Rice is the main food crop for Indonesians; hence, increasing population leads to expanding demand for this commodity. This research was carried out over potential acid sulfate soils of tidal swamplands in Matang Danau village, Sambas regency, West Kalimantan during 2018 Dry Season. The aim of the research was to evaluate grain yields and the variability of ten rice varieties. The study employed completely randomized block design with three replications. Ten rice varieties, namely Inpara 1, Inpara 2, Inpara 3, Inpara 4, Inpara 6, Inpara 8, Inpara 9, Margasari, Inpari 32 and Cillosari (as control) were investigated. The results showed that all varieties performed good phenotypic acceptabilily (score 3), without symptoms of Fe toxicity. Yielded grain ranged from 2.44 to 5.39 tons/ha in dry milled grain. The highest yield was shown by Inpari 32 (5.33 t/ha) and Inpara 1 (5.39 t/ha), suggesting that these varieties suit acid sulfate soils as an alternative to existing Cilosari cultivar.
Does the exposure of water shortage in peat soil affect the nutrient uptake of seedlings between different oil palm varieties?
Authors: Farrasati Rana , Muhayat  , Ginting Eko N , Pradiko Iput , Winarna  
Published: July 2022

Abstract
Soil water content is an important property to indicate the quality of peat in supporting plant growth. Soil nutrient is affected by water content, and each plant has varied adaptation to encounter water stress. This study aimed to observe the effect of water stress to leaf nutrients, nutrient uptake dynamics, and biomass on oil palm seedlings with three different varieties (540, Langkat, Dumpy) and four different water stoppage periods (0, 14, 21, 28 days). Results showed that after 28 days, biomass, leaf nutrients, and plant nutrient uptake (N, P, K, Ca, Mg) from 3 varieties were not statistically different. However, different N, P, K, and Mg uptake only occurred if we compared watering period’s data. The highest water content and biomass correlation were shown in Langkat variety (r = -0.630). The pH increased longest water stoppage period (r = 0.116). Significant correlation was only found in Langkat and Dumpy’s N uptake (r = -0.431 - (- 0.420)), and P uptake of Langkat (r = -0.368). Sensitivity order of nutrient uptake in relation with low water content for 540 variety was N > Ca > Mg > P > K; Langkat variety was N > Ca > Mg > P > K, and Dumpy variety was N > Ca > P > Mg > K.
Understanding Material Selection Challenges in Geothermal Well and Systematic Qualification Approach
Authors: Tayactac R G , Manuel M C 
Published: July 2022

Abstract
Geothermal wells are usually operated under High Temperature High Pressure (HTHP) conditions where corrosion is the major threat to the well integrity. As a result, high operation cost and production time loss due to a short life span of steel casing reported in less than two years. This paper describes a study of the casing problems and failures observed in geothermal wells and a possible approach to optimize material selection and qualification of geothermal wellhead system materials.
Effect of Increasing Solar Radiation Reflected with Mirrors Perpendicularly on the Power Output of Photovoltaic System with Cooling
Authors: Kolamroudi Mohammad Karimzadeh , Ilkan Mustafa , Egelioglu Fuat , Safaei Babak 
Published: July 2022

Abstract
Solar energy is one of the most popular renewable energies in the world as solar energy can be easily accessed throughout most places of the world. However, converting solar energy into other sources of energy is not very cheap and numerous efficiency improvements methods are under investigation by researchers around the world. The current study proposes a low concentration photovoltaic system (LCPVS) with 4 mirrors and cooling. The aim of this project was to examine how using mirrors to concentrate solar radiation affects the amount of power generated by solar panels. The mirrors (ranging from 1 to 4) radiated the sun reflection onto the panel with a cooling system. The results obtained from the proposed project were compared to the results collected from the normal panel without concentration to measure the differences which revealed that the proposed system output power was almost three times more than conventional photovoltaic (PV) panel without concentration.
A Review – Earth-air Heat Exchanger: Applications, Advances and Challenges
Authors: Zeitoun Wael , Lin Jian , Siroux Monica 
Published: July 2022

Abstract
Due to global warming and energy security, renewable energy systems became a subject of interest in research. Earth-air heat exchanger is one of these systems that can decrease the primary energy consumption using shallow layers of the ground as a source or sink of heat. Different configurations and designs of EAHEs were under research to assess their performance and find the optimal designs. It is important to identify and classify these designs to further develop innovative research on this topic. This review sheds light on the different classifications of EAHEs and their applications.
Wave Conditions Variation Effects on Energy Recovery for a Dexa Wave Energy Converter
Authors: Jabrali Ahmed , Khatyr Rabha , Naciri Jaafar Khalid 
Published: July 2022

Abstract
The aim of this paper is to present the effects of wave amplitude and wave frequency variations on the energy recovered by a DEXA Wave, which is a wave energy converter (WEC) device. The two-body articulated floating WEC consists of two connected rigid bodies, the energy is recovered by taking advantage of the relative movement between the two parts set in motion differently by the wave. The results show that the value of the wave amplitude and wave period have an impact on the recovered energy by the WEC. The present work shown that for this type of WEC, an increase in the amplitude of the wave does not necessarily improve the energy recovered by the WEC also it is shown that the considered WEC could be typical for low wave amplitude areas.
Comparative Study of Biogas Production from Cassava Pulp in a Sequencing Batch Reactor and a Continuous Stirred Tank Reactor
Authors: Ruttithiwapanich T. , Waewsak C. , Laopitinan O. , Saengchan K. , Lueangwattanapong K. , Songkasiri W. 
Published: July 2022

Abstract
Thai cassava starch industry generates solid waste or pulp approximately of 9.5 Mt/y (with a moisture content of 70–80%). Biogas production technology has been introduced for several decades in Thailand. However, the implementation of biogas production using cassava pulp as a feedstock is still limited due to the complex lignocellulosic structure, which diminishes hydrolysis. This work investigated biogas production from cassava pulp in a 50-m3 pilot-scale sequencing batch reactor (SBR) and continuous stirred tank reactor (CSTR). Both reactors were fed with cassava pulp, under the organic loading rate (OLR) of 8 kg-COD/m3-d and the average hydraulic retention time (HRT) of 7 d. Under the batch operation, more than 60% of the starch content was utilized within the first three days. The SBR achieved methane production of 1.87 m3-CH4/ton-pulpfresh-d and acids production of 2.19 kg-TVA/ton-pulpfresh-d while the CSTR had methane production of 0.22 m3-CH4/ton-pulpfresh-d and acids production of 7.07 kg-TVA/ton-pulpfresh-d. The methane production was higher in the SBR because the settling process helped microorganisms remain in the system. In CSTR, acids rather than methane were produced due to the washout of methanogenic microorganisms. This work revealed that the SBR yielded higher biogas production, while the CSTR produced intermediate acids, which could be supplied to the biochemical industry.