bluuebunny/crossref_metadata_2025_split huggingface dataset:
The PoliTO-UniRoma1 database of cyclic and dynamic laboratory tests: assessment of empirical predictive models
Authors: Ciancimino Andrea , Cosentini Renato Maria , Foti Sebastiano , Lanzo Giuseppe , Pagliaroli Alessandro , Pallara Oronzo 
Published: April 2022

Abstract
The soil nonlinear hysteretic behaviour is usually described, in the moderate strain range, through the shear modulus reduction and material damping ratio (MRD) curves. In the common practice, in absence of specific laboratory tests, the curves are estimated by employing empirical regression models. Such predictive models, typically calibrated on large experimental datasets, correlate the soil response to its physical properties. This research fits within this context, presenting a comprehensive database of cyclic and dynamic laboratory tests conducted on natural Italian soils. The database, publicly available as supplementary data of the paper, contains the results of the tests conducted by the geotechnical laboratories of the Politecnico di Torino (Turin, Italy) and the Sapienza Università di Roma (Rome, Italy) over the past 30 years. The experimental data are employed to assess the performance of some widely used empirical models in predicting the MRD curves of natural uncemented fine-grained soils, emphasizing the importance of using an independent dataset for conducting a reliable statistical analysis. The results show that the use of many soil parameters as proxies for predicting the soil response does not necessarily lead to an improvement in the performance of the model. Therefore according to Occam’s razor principle, simple models are to be preferred.
Near-infrared fluorescence axillary reverse mapping (ARM) procedure in invasive breast cancer: relationship between fluorescence signal in ARM lymph nodes and clinical outcomes
Authors: Abbaci Muriel , Conversano Angelica , Karimi Maryam , Mathieu Marie-Christine , Rouffiac Valérie , De Leeuw Frederic , Michiels Stefan , Laplace-Builhé Corinne , Mazouni Chafika 
Published: April 2022

Abstract

Introduction: Near-infrared (NIR) fluorescence axillary reverse mapping (ARM) procedure is a promising tool to identify and preserve arm lymphatic drainage during axillary lymph node dissection (ALND). The ARMONIC clinical trial was conducted to validate the technique on a large cohort of patients and to analyse predictive clinical factors for ARM lymph node metastasis. For the first time, the fluorescence signal intensity from the ARM lymph nodes was measured and correlated with clinical findings. Materials and methods: 109 patients with invasive breast cancer with an indication of mastectomy and ALND underwent the NIR fluorescence ARM procedure. Indocyanine green was administered by intradermal injection followed by the intraoperative identification and resection of ARM lymph nodes with NIR fluorescence camera guidance. Fluorescence signal intensity and signal distribution were then measured ex vivo and compared with clinical outcomes.Results: ARM lymph nodes were successfully identified by fluorescence in 94.5% of cases. The mean normalised fluorescence signal intensity value was 0.47 with no significant signal difference between metastatic and non-metastatic ARM lymph nodes (p=0.3728). At the microscopic level, fluorescence signal distribution was focally intense in lymphoid tissue areas. Only preoperative diagnosis of metastasis in the axillary nodes of patients was significantly associated with higher ARM node fluorescence signal intensity (p=0.0253) but not the pathological nodal (pN) status (p=0.8081). Based on an optimal cut-off fluorescence value, the final sensitivity and specificity of NIR fluorescence ARM procedure for ARM lymph node metastatic involvement was 64.7% and 47.3%, respectively.Conclusion: Although our preliminary results did not show fluorescence signal intensity is a reliable diagnostic tool, NIR fluorescence ARM procedure may be useful for ARM lymph node identification. Clinical trial registration: NCT02994225
Analysis and Design of Ultra-Wideband PRGW Hybrid Coupler Using PEC/PMC Waveguide Model
Authors: Mousavirazi Zahra , Ali Mohamed Mamdouh M. , Gheisanab Hassan Naseri , Denidni Tayeb A. 
Published: April 2022

Abstract
In this paper, a new method to facilitate the design of Printed Ridge Gap Waveguide (PRGW) structures is introduced. One of the main difficulties in designing such structures is related to their simulation process which is really time and energy-consuming. Therefore, a suitable boundary condition is considered to bring about the primary structure without involving the bed of nails or mushroom unit cells. Using this technique, a wideband PRGW 3dB hybrid double-box coupler is designed to serve in mm-wave frequencies at a center frequency of 30 GHz, which can be deployed for the next generation of mobile communication. The designed coupler provides a wide matching and isolation bandwidth with low output amplitude imbalance, which is unique in comparison with current couplers. The prototype of the proposed coupler is fabricated and measured where the simulation and measurement results show a good agreement indicating the strength of the proposed method in PRGW structure design as well. The measured results show the couplers achieve better than 10-dB return loss and isolation over the frequency range from 25 to 40 GHz (46% BW) with the power-split unbalance and phase error within ±1 dB and ±5 degrees, respectively. In addition, square mushrooms are chosen here to satisfy the high impedance surface. Not only do they bring about larger stop bandwidth, but also their configuration facilitates the arrangement of them around the coupler. The proposed design has superb characteristics such as low profile, low loss, and easy integration with microwave circuits and systems that can be suitable for designing mm-wave beamforming networks.
Description of pathogenic bacteria in patients with respiratory symptoms associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Colombia
Authors: Zuluaga Nathalia , Martínez David , Hernández Carolina , Ballesteros Nathalia , Castañeda Sergio , Ramírez Juan David , Muñoz Marina 
Published: April 2022

Abstract
Viral respiratory infections may predispose to co-infections with other pathogenic microorganisms. In this study, pathogenic respiratory bacteria were detected in patients with and without severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suffering respiratory symptoms such as cough, fever, odynophagia, rhinorrhea, respiratory distress, and fatigue. Patients without respiratory symptoms were included as controls. Haemophilus influenzae and Streptococcus pneumoniae were the main bacteria found in patients with respiratory symptoms (including hospitalized patients) in both positive and negative for SARS-CoV-2 infections. Pathogenic bacteria possibly proliferate due to the limited immune response of patients with SARS-CoV-2, perhaps due to dysbiosis generated by the viral infection.
Prioritize biologically relevant ions for data-independent acquisition (BRI- DIA) in LC-MS/MS-based lipidomics analysis
Authors: Duan Likun , Scheidemantle Grace , Lodge Mareca , Cummings Magdalina J , Pham Eva , Wang Xiaoqiu , Kennedy Arion , Liu Xiaojing 
Published: April 2022

Abstract
Introduction Data-dependent acquisition (DDA) is the most commonly used MS/MS scan method for lipidomics analysis on orbitrap-based instrument. However, MS instrument associated software decide the top N precursors for fragmentation, resulting in stochasticity of precursor selection and compromised consistency and reproducibility. We introduce a novel workflow using biologically relevant lipids to construct inclusion list for data-independent acquisition (DIA), named as BRI-DIA workflow. Objectives To ensure consistent coverage of biologically relevant lipids in LC-MS/MS-based lipidomics analysis. Methods Biologically relevant ion list was constructed based on LIPID MAPS and lipidome atlas in MS-DIAL 4. Lipids were extracted from mouse tissues and used to assess different MS/MS scan workflow (DDA, BRI-DIA, and hybrid mode) on LC-Orbitrap Exploris 480 mass spectrometer. Results DDA resulted in more MS/MS events, but the total number of unique lipids identified by three methods (DDA, BRI-DIA, and hybrid MS/MS scan mode) is comparable (580 unique lipids across 44 lipid subclasses in mouse liver). Major cardiolipin molecular species were identified by data generated using BRI-DIA and hybrid methods and allowed calculation of cardiolipin compositions, while identification of the most abundant cardiolipin CL72:8 was missing in data generated using DDA method, leading to wrong calculation of cardiolipin composition. Conclusion The method of using inclusion list comprised of biologically relevant lipids in DIA MS/MS scan is as efficient as traditional DDA method in profiling lipids, but offers better consistency of lipid identification, compared to DDA method. This study was performed using Orbitrap Exploris 480, and we will further evaluate this workflow on other platforms, and if verified by future work, this biologically relevant ion fragmentation workflow could be routinely used in many studies to improve MS/MS identification capacities.
Antarctic krill (Euphausia superba) distributions, aggregation structures and predator interactions in Bransfield Strait
Authors: Annasawmy Pavanee , Horne John K , Reiss Christian S , Cutter George R , Macaulay Gavin J 
Published: April 2022

Abstract
Aggregation structures of Antarctic krill (Euphausia superba) and predator interactions were investigated using active acoustic data collected for approximately one month by WBAT and Signature100 echosounders deployed on moorings in two hydrographically different sites in Bransfield Strait. Near Nelson Island, water flows from the northwest to southeast while Deception Island is influenced by the Bransfield Front with stronger net current velocities from the southwest to northeast. Krill aggregations were identified and then classified in three clusters using a swarm-identification algorithm and hierarchical clustering using aggregation morphological characteristics: acoustic density, mean depth, center of mass, inertia, equivalent area, aggregation index, and proportion occupied. A total of 693 and 736 aggregations were detected at the mooring sites close to Nelson and Deception Islands. The three aggregation categories ranged from high to low densities, evenness and dispersion and were distributed throughout the water column. Krill aggregation densities and mean thickness are influenced by current velocities, direction, mean depth, and predator foraging. The majority of observed predator dive profiles occurred over the aggregation type with highest krill densities at both Nelson and Deception Islands, and within the first 25 m of the water column. The heterogeneity of krill aggregations potentially impacts predator foraging strategies and predator-krill interactions in the hydrodynamically active Bransfield Strait.
COVID19 induced immunosuppression and aggressive progression of primary cranial vault lymphoma presented as a management challenge, a case report, and a review of the literature.
Authors: Jha vikas Chandra , Alam Mohammad shahnawaz 
Published: April 2022

Abstract

Primary Large cell Non-Hodgkin's Lymphoma of the cranial vault is rare and association with COVID19 needs to be studied as in our patient.Our patient, a 53-year-old male noticed fast growth of posterior cranial vault tumour from 2cm to 10 cm size in last 6months after COVID 19 affliction. MRI brain with contrast revealed lesions mimicking multicentric meningioma. The whole-body PET scan was normal. Following Subtotal excision of the mass, histopathology revealed large B-cell Non-Hodgkin's lymphoma (DLBCL). Immunohistochemistry showed positive for CD10, CD20, CD45 (LCA), ALK, and BCL-VE with Ki-67 index 90–95%. Following radiotherapy and chemotherapy patient is disease-free on imaging and doing well at 5 months of follow-up.Early intervention with excisional biopsy and timely chemo and radiotherapy in presence of favourable immunostaining may add survival benefit even in the presence of malignant features induced by immunosuppressing disease as COVID19.Although this association was noticed in this single case study but role of Covid 19 infection in inducing the fast progression of tumours which can be expedited in immunosuppressive condition cannot be ignored.
Effects of changes of osteocyte shape on fluid flow and fluid shear stress of loaded bone
Authors: Yu WeiLun , Huo Xuyang , Li Hongliang , Yang Fengjian , Qi Qiuju , Wu Xiaogang , Chen Weiyi 
Published: April 2022

Abstract
Background: Load-induced pressure gradients (PG) result in interstitial fluid flow in bone tissue, which is not only provides sufficient nutrient supply and metabolic pathway for the bone cells, but also enables bone cells to accept external mechanical signals. Methods: We calculate the number and distribution of bone canaliculus around the osteocyte based on the varying shape of osteocyte, and then use these calculated parameters and other microstructure data of bone tissue to estimate the anisotropy permeability of the lacunar–canalicular. Finally, according to the calculated parameters, the poroelastic finite element models of the osteon are established, and the influence of the osteocyte shape on the fluid flow properties of osteon under the axial displacement load is analyzed. Two kinds of boundary conditions are considered on the cement line of osteon, elastic restrained (BC1) and displacement confined (BC2). Results: In the range of parameters we studied, the changes of osteocyte shape (Case1-Case6) make the maximum value of PG, pore pressure (PP), fluid velocity (FV) and fluid shear stress (FSS) 33.36%, 67.67%, 8.6% and 26.6% larger than the Reference model in BC1, respectively. And the maximum value of PG, PP, FV and FSS are 65.39%, 67.67%, 8.4% and 29% larger than reference model in BC2. The maximum PG, PP, FV and FSS in BC2 are 96.72%, 95.51%, 97.87% and 97.13% larger than that in BC1, respectively. The permeability of elongated osteocyte model (Case 3, Case 4 and Case 6) have a difference of one magnitude order in X and Y direction. Conclusion: The changes of osteocyte shape has a significant impact on the degrees of anisotropy for fluid flow and porous media of osteon. This model can facilitate better accurately quantifying the fluid flow in lacuna-canalicular system.
Comparison of Self Versus Expert-assisted Feedback for Cricothyroidotomy Training
Authors: Aldinc Hasan , Gun Cem , Yaylaci Serpil , Senuren Cigdem Ozkaya , Guven Feray , Sahiner Melike , Kayayurt Kamil , Turkmen Suha 
Published: April 2022

Abstract
The self-video feedback method may have the potential to provide a low-cost alternative to physician-driven simulation-based training. This study aimed to assess the utility of video feedback by comparing the improvement in procedural performance when trainees received self-video feedback (trainees review their performance alone) and expert-assısted video feedback (trainees review their performance while an emergency physician provides additional feedback). This study was performed at a university simulation center with 89 final-year medical students and used a cricothyroidotomy simulation model. Following the educational presentation and the best practice video, trainees were randomized into two groups (self video-feedback and expert assisted video-feedback). They performed the cricothyroidotomy before and after the feedback, The procedures were recorded and scored. Scoring were made using a pre-defıned checklist. Mann Whitney U test and Wilcoxon test were used to analyze non-normally distributed data. For the analysis of normally distributed data, Student t-test and Paired Samples t-test were used. Results demonstrated significant improvement in cricothyroidotomy performance with both types of video feedback. The improvement was significantly greater in the expert-assisted video feedback group. We think that simulation-based training is effective with self video feedback.
„Teachers’ Beliefs“: Inklusionsbezogene Überzeugungen von angehenden Lehrkräften hinsichtlich eines gemeinsamen Unterrichts
Authors: Endres Annika , Risch Björn , Schehl Marie , Weinberger Philip 
Published: April 2022

Professionelle Kompetenz gilt als zentrale Handlungsressource unterrichtlichen Handelns. Berufsbezogene Überzeugungen und Werte (beliefs) können dessen Qualität maßgeblich beeinflussen und sind Gegenstand zahlreicher empirischer Untersuchungen. Eine Vielzahl von Forschungsvorhaben präzisieren den gewählten Beliefbegriff hinsichtlich fachwissenschaftlicher, fachdidaktischer oder (sonder)pädagogischer Fragestellungen. In dem vorliegenden Beitrag wird zunächst unser Begriffsverständnis von professioneller Handlungskompetenz, Inklusion und Teachers’ Beliefs theoretisch begründet. Von diesen Betrachtungen ausgehend, wird das Forschungsdesign einer qualitativen Studie abgeleitet, welches die inklusionsbezogenen Überzeugungen von angehenden Lehrkräften hinsichtlich eines gemeinsamen Unterrichts beschreibt sowie Implikationen für die Hochschullehre aus Studierendenperspektive ermöglicht. Die Ergebnisse geben Aufschluss über das Heterogenitätsverständnis von Lehramtsstudierenden der Regelschule, deren vorherrschenden Rollenbildern und ideellen Überzeugungen zu inklusivem Unterricht. Sie skizzieren außerdem hochschuldidaktische Maßnahmen, welche aus Studierendenperspektive einen Beitrag für die Vorbereitung im Unterricht inklusiver Klassen leisten können. Konsequenzen, die sich aus unserer Sicht für die Ausbildung von Lehramtsstudierenden ergeben, werden mit Fokus auf die Entmystifizierung inklusionsbezogener Überzeugungen diskutiert.Abstract
Professional competence is regarded as a central resource for teaching action. Job-related beliefs and values (beliefs) can significantly influence its quality and are the subject of numerous empirical studies. Research projects in various fields of educational science specify the chosen concept of belief with regard to scientific, didactic or (special) pedagogical questions. In this article, our understanding of the concepts of professional competence, inclusion and the teacher belief is first theoretically justified. Based on these considerations, the research design of a qualitative study is derived, which allows to describe the inclusion-related future teachers' beliefs regarding joint teaching as well as implications for higher education teaching from the student perspective. The results provide information about the heterogeneity of students in mainstream schools, prevailing role models, and ideological ideas about inclusive teaching. They also outline university didactic measures which, from a student perspective, can contribute to the preparation of inclusive classes. Consequences which, in our view, arise for the training of student teachers are discussed with a focus on demystifying inclusion-related convictions.
A stochastic simulation-based risk assessment method for water allocation under uncertainty
Authors: Chen Shu , Yuan Zhe , Lei Caixiu , Li Qingqing , Wang Yongqiang 
Published: April 2022

Abstract
There are a lot of uncertainties in the water resources system, which makes the water allocation plan very risky. In order to analyze the risks of water resources allocation under uncertain conditions, a new methodology called the stochastic simulation-based risk assessment approach is developed in this paper. First, the main hydrological stochastic variable is fitted by a proper probability distribution. Second, suitable two-stage stochastic programming is constructed to obtain the expected benefit and optimized water allocation targets. Third, the Monte Carlo method is used to obtain a suitable stochastic sample of the hydrological variable. Fourth, a pre-allocated water optimization model is proposed to obtain optimized actual benefit. The methodology can give a way for risk analysis of water allocation plans obtained by uncertain optimization models, which provides reliable assistance to water managers in decision-making. The proposed methodology is applied to the Zhanghe Irrigation District and the risk of the water allocation plan obtained under the randomness of annual inflow is assessed. In addition, three different division methods of the annual inflow are applied in the first step, namely three levels, five levels and seven levels, respectively. From the results, the risk of the water allocation scheme obtained by the TSP model is 0.372–0.411 and decreases with the increase of the number of hydrological levels. Considering both the risk and model complexity, seven hydrological levels are recommended when using the TSP model to optimize water allocation under stochastic uncertainty.
Coliform removal efficacy of polyurethane foam impregnated with chitosan nanoparticles and silver/silver oxide nanoparticles
Authors: Sasidharan Anjali P. , V Meera , Raphael Vinod P. 
Published: April 2022

Abstract
This study was intended to synthesise, characterise and evaluate the antibacterial activity and Escherichia coli removal efficacy of a novel polyurethane foam impregnated with nanochitosan and nanosilver/silver oxide (PFCA). The study also exposed the effectiveness of nanochitosan as a disinfectant and as a binder for AgNPs, which has not been explored so far. The E. coli removal mechanism and antibacterial activity of PFCA were established by FTIR spectroscopy, XRD pattern and SEM analysis. PFCA achieved complete removal of E. coli with sufficient reusing capacities and possessed 100% antibacterial efficiency in a bacterial suspension of 5 × 106 CFU/mL. The study also showed that varying pH from 5 to 9 did not make any significant changes in the removal of E. coli. The presence of co-existing ions and organic matter did not reduce the efficiency of PFCA. The elution of silver ions (a very common limitation in treatment processes involving silver ions) was found to be much less, well below the drinking water limit. The study proved excellent potential of PFCA in removing E. coli, making it a viable disinfectant for water/wastewater treatment.
Facial Asymmetry Detected with 3D Methods in Orthodontics: A Systematic Review
Authors: Pedersoli Laura , Dalessandri Domenico , Tonni Ingrid , Bindi Marino , Isola Gaetano , Oliva Bruno , Visconti Luca , Bonetti Stefano 
Published: April 2022

Background:
Historically, the development of two-dimensional (2D) imaging techniquesforerun that of three-dimensional (3D) ones. Some 2D methods are still considered valid and effective to diagnose facial asymmetry but 3D techniques may provide more precise and accurate measurements.

Objective:
The aim of this work is to analyze the accuracy and reliability of the imaging techniques available for the diagnosis of facial asymmetry in orthodontics and find the most reliable.

Methods:
A search strategy was implemented using PubMed (National Library of Medicine, NCBI).

Results:
A total of 3201 papers were identified in electronic searches. 90 articles, available in full text, were included in the qualitative synthesis consisting of 8 reviews on the diagnosis of facial asymmetry, 22 in vivo and in vitro studies on 2D methods and 60 in vivo and in vitro studies on 3D methods to quantify the asymmetry.

Conclusion:
2D techniques include X-ray techniques such as posterior-anterior cephalogram, which still represents the first level exam in the diagnosis of facial asymmetry. 3D techniques represent the second level exam in the diagnosis of facial asymmetry. The most current used techniques are CBCT, stereophotogrammetry, laser scanning, 3D optical sensors and contact digitization. The comparison between bilateral parameters (linear distances, angles, areas, volumes and contours) and the calculation of an asymmetry index represent the best choices for clinicians who use CBCT. The creation of a color-coded distance map seems to represent the most accurate, reliable and validated methods for clinicians who use stereophotogrammetry, laser scanning and 3D optical sensors.