bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Gamma Oryzanol on prevention of surgical induced endometriosis development in rat model
Authors: Eisalou Mohammad Yari , Farahpour Mohammad Reza 
Published: February 2022

AbstractInfertility is believed to be triggered by endometriosis whose pathophysiology and the etiology is still unknown. Certain genes play pivotal roles in pathogenesis of endometriosis. Natural products and plants are used as important sources for production of new drugs. The current study assesses the effects of gamma-oryzanol (GO) in a rat model with surgically induced endometriosis. The experimental endometriosis was induced in 24 wistar rats, and the animals were subsequently subdivided into endometriosis-sole (endom group), 3000 and 6000 µg/kg GO (GO-3000 and GO-6000) and Vit C groups. The protein levels of estrogen receptor-alpha (ER-α), Steroidogenic factor 1 (SF1), Sirtuin 1 (SIRT1), heme oxygenase 1 (HO1), light chain 3 (LC3B) and Beclin1 (BECN1) were assessed. TUNEL staining was used for detecting the apoptosis rate. The results revealed that protein levels of SF1, HO1, and total LC3B significantly (P < 0.05) decreased in GO-6000-treated groups compared to endom group. Moreover, the protein level of BECN1 and SIRT-1 significantly (P < 0.05) increased in GO-6000-treated groups compared to endom group. GO treatment did not imply any significant difference (P > 0.05) concerning the protein levels of ER-α. The TUNEL staining results showed higher TUNEL-positive cells reactions in the rats treated with GO-6000 and Vit C. Thus, GO is involved in improving condition rats involved with endometriosis through modulation in the protein levels of some molecules and also induction of apoptosis.
Deep water inflow slowed offshore expansion of the West Antarctic Ice Sheet at the Eocene-Oligocene transition
Authors: Uenzelmann-Neben Gabriele , Gohl Karsten , Hochmuth Katharina , Salzmann Ulrich , Larter Robert D. , Hillenbrand Claus-Dieter , Klages Johann P. ,   Science Team of Expedition PS104, Afanasyeva V. , Arndt J. E. , Bickert T. , Bohaty S. M. , Dziadek R. , Ebermann B. , Ehrmann W. , Esper O. , Frederichs T. , Freudenthal T. , Gebhardt C. , Küssner K. , Kuhn G. , Najman Y. , Pälike H. , Riefstahl F. , Ronge T. , Scheinert M. , Simoes Pereira P. , Smith J. A. , Spiegel C. , Van de Flierdt T. , Zundel M. 
Published: February 2022

AbstractThe stability of the West Antarctic Ice Sheet is threatened by the incursion of warm Circumpolar Deepwater which flows southwards via cross-shelf troughs towards the coast there melting ice shelves. However, the onset of this oceanic forcing on the development and evolution of the West Antarctic Ice Sheet remains poorly understood. Here, we use single- and multichannel seismic reflection profiles to investigate the architecture of a sediment body on the shelf of the Amundsen Sea Embayment. We estimate the formation age of this sediment body to be around the Eocene-Oligocene Transition and find that it possesses the geometry and depositional pattern of a plastered sediment drift. We suggest this indicates a southward inflow of deep water which probably supplied heat and, thus, prevented West Antarctic Ice Sheet advance beyond the coast at this time. We conclude that the West Antarctic Ice Sheet has likely experienced a strong oceanic influence on its dynamics since its initial formation.
Explorations into the sustainable synthesis of cyclic and polymeric carbonates and thiocarbonates from eugenol-derived monomers and their reactions with CO2, COS, or CS2
Authors: Sengoden Mani , Bhat Gulzar A. , Darensbourg Donald J. 
Published: February 2022

The natural product, eugenol, which can be acquired from the flower buds of clove, was converted to an epoxide in excellent yield and examined for its reactivity with CO2 and its sulfur congeners in the presence of metal and organo-catalysts.
Voice Handicap Index Changes After Microflap Surgery for Benign Vocal Fold Lesions Are Not Associated With Recommended Absolute Voice Rest Duration
Authors: King Renee E. , Novaleski Carolyn K. , Rousseau Bernard 
Published: February 2022

Purpose:
Voice rest is frequently prescribed after phonosurgery, but optimal type and duration for voice outcomes have not been demonstrated. Studies to date have been characterized by heterogeneity in surgical procedures and laryngeal diagnoses. We sought to analyze the effect of recommended absolute voice rest duration on outcomes of microflap surgery for benign vocal fold lesions. A secondary purpose was to identify patient factors associated with postoperative voice outcomes.

Method:
Forty-three patients were included in this retrospective review of patients aged 18 years and above who underwent direct microlaryngoscopy with microflap for vocal fold polyp or cyst over a 5-year period at a multidisciplinary voice center. Duration of recommended postoperative absolute voice rest was classified as less than 7 days, 7 days, and more than 7 days. Demographic and vocal hygiene data and voice treatment history were collected. Outcome measures consisted of one pre- and two postoperative Voice Handicap Index (VHI) scores. Effects of recommended voice rest on outcomes were analyzed using mixed models for repeated measures. Effects of patient factors on outcomes were analyzed as exploratory measures. Stroboscopy ratings were analyzed descriptively.

Results:
Thirteen patients were recommended 7 days of absolute voice rest, 15 were recommended less than 7 days, and 15 were recommended more than 7 days. Postoperatively, VHI scores significantly improved for all patients. Voice rest as a continuous variable was associated with the Functional subscale score in the short term, but there was no effect on VHI total score and no longer term effect of voice rest on any outcome. Age, sex, and preoperative voice therapy were associated with at least one VHI subscale score on at least one time point.

Conclusion:
VHI outcomes of microflap surgery for polyps and cysts do not differ by duration of recommended absolute postoperative voice rest.

Supplemental Material:

https://doi.org/10.23641/asha.19178459
Words Versus Pictures: Bilingual Performance on Verbal and Pictorial Measures of Executive Functions
Authors: Alateeq Halah , Azuma Tamiko 
Published: February 2022

Purpose:
This study examined bilinguals' performance on functional executive function map tasks such as the Zoo Map from the Behavioural Assessment of the Dysexecutive Syndrome and the extent to which working memory, set-shifting, and inhibition measures predicted bilinguals' performance on these tasks. Additionally, we explored the utility of pictorial map tasks as a measure of complex executive function in bilinguals. We hypothesized that bilinguals would perform better on the pictorial map tasks due to the reduced language processing demand.

Method:
The analyses included 131 bilingual young adults who completed a comprehensive language history questionnaire, an English proficiency test, a battery of working memory and executive function tasks, and verbal and pictorial map tasks.

Results:
Contrary to predictions, bilinguals' performance on the verbal maps did not differ significantly from that on the pictorial maps. Two multiple regression models significantly predicted performance on the verbal and pictorial maps, accounting for 7%–25% of the variance in the map scores. Working memory and interference control were the most prominent predictors within these models.

Conclusions:
In our study, bilinguals' performance on the verbal maps did not differ significantly from that on the pictorial maps. Additionally, English proficiency did not correlate with the participants' verbal map scores. These results suggest that executive function map tasks (e.g., the Zoo Map) are a useful clinical tool for assessing executive function in bilinguals. The findings of this study are discussed in light of the current literature on executive functions in bilinguals.
Influence of musical elements on the perception of ‘Chinese style’ in music
Authors: Zhang Yu , Zhou Ziya , Sun Maosong 
Published: February 2022

AbstractRecently Chinese music has been regarded as an independent music school. However, the definition of Chinese music has been an abstract and subjective concept. That makes music information retrieval (MIR) tasks hard to perform on Chinese music. Previous musicological studies have explained how musical elements like melody and instruments shape a certain kind of music genre including Chinese music, but the findings cannot be directly applied to relevant MIR tasks towards large‐scale users and real‐world problems. In this study, a pipeline of performing a perceptual survey is designed to explore how different musical elements influence people's perception of ‘Chinese style’ in music. Participants with various backgrounds were presented with categorised music excerpts performed in the Erhu or violin and then gave ‘Chinese style’ ratings. Statistical analysis indicates that music content contributes more than instruments. Results were compared between musicians and non‐musicians. Subsequently, a supplementary automatic music classification experiment is conducted in comparison with the survey results to discuss the authors’ choice of stimuli in the survey and similarities between computer auditory and human perception. In general, the results in this study can be useful for MIR tasks, such as understanding, representation, and recommendation of Chinese music.
Analysis on the mechanism of sound production and effects of musical flue pipe
Authors: Jiang Jing , Liu Jingyu , Li Zijin , Zhang Tingyu , Yang Hong 
Published: February 2022

AbstractString instruments, wind instruments and percussion instruments are three traditional categories of musical instruments, among which wind instruments play an important role. Usually, pitches of wind instruments are determined by the vibrating air column, and the musical pitches will be affected by multiple factors of the air flow. In this article, the mechanism of sound production by a pipe is analysed in terms of the coupling of the edge tone and the air column's vibration in the tube. Experiments and computational fluid dynamics numerical calculations are combined to study the influence of the jet velocity on the oscillation frequency of the edge tone and the musical sound produced by the tube, which help to gain deeper insight into the relation between physics and music.
Impartial near‐optimal control and sizing for battery hybrid energy system balance via grey wolf optimizers: Lead acid and lithium‐ion technologies
Authors: Ramadan Haitham S. , Haes Alhelou Hassan , Ahmed Abdelsalam A. 
Published: February 2022

AbstractThe balance of renewable‐energy‐based power systems has witnessed significant importance particularly with their rapid integration within these systems. The optimal sizing and control of energy storage systems (ESS) in hybrid power systems (HPSs) based on renewable energy becomes of particular interest. In this research, the HPS under study comprises PV, wind, and energy storage system. Two battery technologies, lead acid (LA) and lithium‐Ion (LI)—are conducted to reach a near‐optimal solution via metaheuristic optimization algorithms in HPS. This paper aims at reaching the equilibrium of the generation consumption for HPS through applying a novel technique, grey wolf optimization (GWO) through the optimal battery sizing of the HPS. The optimization is used for reaching the due balance between the production of power and that absorbed by the load, by minimizing the difference between the final and initial state of charge. Based on numerical simulations, the two different battery technologies are considered in the sizing of the ESS using GWO approach. From the simulation results, the proposed GWO leads to more enhanced performance with LI rather than LA by 3.1% with reduced number of parallel/series cells (Np/Ns) of 240/3450 and 270/3500. Accordingly, the GWO provides an adequate dynamic controlled performance.
Effect of Fatigue and Graded Running on Kinematics and Kinetics
Parameters in Triathletes
Authors: Mateus Greyce Any Sousa , Assumpção Claudio Oliveira , Cabido Christian Emmanuel Torres , Veneroso Christiano Eduardo , Oliveira Saulo Fernandes Melo , Fermino Rogério César , Mortatti Arnaldo , Lima Leonardo Coelho Rabellode , Vilas Boas Joao Paulo , Banja Fernandes Túlio Luiz 
Published: February 2022

AbstractThis study aimed to evaluate the effect of cycling-induced fatigue on subsequent
running with different ground inclinations on triathletes. Twenty male
triathletes ran on a treadmill at individual speeds, on three inclines: level
(0%), 7% uphill (7%), and 7% downhill
(−7%). Subsequently, the athletes performed an incremental
ramp-to-exhaustion (RTE) protocol on an ergometric bicycle until task failure
and repeated the running protocol (POST-RTE). During running and cycling was
monitored perceived exertion (RPE) and heart rate (HR). Plantar pressure
distribution, peak plantar pressure, total foot area, and ground contact time
were measured by an in-shoe sensor. Analysis of variance showed that HR
(p=0.001; η2=0.63) and RPE (p=0.001;
η2=0.82 large effect) were higher in POST-RTE, without
interactions between slopes and fatigue. The heel load showed difference between
0 and 7% and 7 and −7% (p=0.001;
η
2=0.44 large effect) with higher value in
−7%. The midfoot showed differences between 0 and
−7% with higher value in 0% (p=0.03;
η
2=0.15 small effect). The contact time
showed interactions between fatigue and slopes with a higher value in POST-RTE.
Coaches should be aware that training on the uphill and downhill surfaces can
alter the plantar load on different foot parts.
Chiral Polyoxygenated Tertiary Alcohols through Kiyooka Aldol Reaction
Authors: Kalesse Markus , Lücke Daniel 
Published: February 2022

AbstractHere we present our work on a Kiyooka aldol protocol for the stereoselective synthesis of tertiary alcohols. In the obtained products, three oxygenated carbon atoms that could further be differentiated flank the chiral tertiary alcohol. This methodology can be applied to simple aromatic or aliphatic aldehydes and more complex substrates bearing a chiral center in the α- and/or β-position. For complex substrates, an unexpected dependency between stereoselectivity and double-bond geometry of the ketene acetal was observed. Furthermore, applications in or towards the synthesis of natural products are presented.1	Introduction2	Scope of the Reaction3	Synthetic Applications4	Conclusion
Complications of Percutaneous Peritoneal Dialysis Catheter
Authors: Oza-Gajera Bharvi P. , Abdel-Aal Ahmed K. , Almehmi Ammar 
Published: February 2022

AbstractA functional peritoneal dialysis (PD) catheter is the cornerstone for the success of renal replacement therapy. This success is largely dependent on adhering to best practices during catheter insertion, which starts with a comprehensive preoperative evaluation that helps in determining the catheter configuration type and both entry and exit sites. Additionally, following the best practice guidelines during PD catheter insertion minimizes undesirable complications and provides a durable functional access for dialysis. However, adverse complications are still encountered despite abiding with these clinical guidelines. These complications are categorized into mechanical and infectious groups. The description and management of these adverse events are discussed in detail in this article with particular attention to the technical pitfalls that can occur during catheter insertion. Avoiding these pitfalls can minimize PD catheter complications and potentially improve clinical outcomes.
Fraturas intertrocantéricas fixadas com parafuso dinâmico de quadril: Ensaio clínico randomizado comparando a via lateral de Hardinge e o acesso minimamente invasivo
Authors: Abreu Eduardo Lima de , Byk Jonas , Westphal Fernando 
Published: February 2022

Resumo
Objetivo Comparar as técnicas de osteossíntese de fraturas intertrocantéricas com o parafuso dinâmico de quadril (dynamic hip screw, DHS, em inglês) pelas vias de acesso de Hardinge e minimamente invasiva do quadril, avaliando o tempo cirúrgico, o grau de dor no pós-operatório imediato, a perda hematimétrica, e os aspectos funcionais de mobilidade ativa.
Métodos Estudo clínico randomizado e duplo-cego, em que 66 pacientes com fratura intertrocantérica foram submetidos a osteossíntese com DHS. Os pacientes foram divididos em um grupo teste, submetidos ao acesso minimamente invasivo, e um controle, em que a cirurgia foi realizada pela via de Hardinge.
Resultados Os pacientes submetidos ao tratamento pela via minimamente invasiva apresentaram um grau de dor pós-operatória inferior em comparação ao grupo tratado pela via lateral de Hardinge (p < 0,001), assim como menor perda hematimétrica (p < 0,001), menor tempo operatório (p < 0,001), e melhora nos testes de mobilidade ativa pós-operatória imediata (p < 0,05).
Conclusão O estudo demonstrou a superioridade clínica nos parâmetros analisados da via de acesso minimamente invasiva em relação ao acesso de Hardinge para a fixação de fraturas intertrocantéricas, quando o DHS for a opção de osteossíntese escolhida.Nível de evidência I.
Devices and Techniques for Percutaneous Creation of Dialysis Arteriovenous Fistulas
Authors: Abdel Aal Ahmed Kamel , Jefferson Xavier , Klusman Carleigh , Garcia Laurynn , Hassanein Haydi , Abdel Aal Talal , Shahin Mohamed M. 
Published: February 2022

AbstractDialysis treatment for chronic kidney disease was first developed by Dr. Willem Kolff in 1943, and its availability began to grow in 1962 after which it has become a mainstay treatment for patients with chronic kidney disease. It is estimated that, in 2021, 15% of adults in the United States (∼37 million people) have chronic kidney disease, of which 661,000 individuals have renal failure, and 468,000 individuals require dialysis. There have been several advancements in dialysis treatment since its advent, most notably the creation of arteriovenous fistulas (AVFs) for venous access in 1966. In recent years, the U.S. Food and Drug Administration approved two new devices for AVF creation using a percutaneous approach. These are the WavelinQ (Becton Dickinson, New Jersey) and the Ellipsys (Avenu Medical, California) endovascular AVF (endoAVF) devices that use radiofrequency and thermal technologies, respectively, to create the AVF. Since the introduction of these technologies, several studies have shown that they are safe and effective, with favorable durability and low rate of serious adverse events. In this article, we will discuss these two devices and the techniques used for percutaneous creation of dialysis AVF as an alternative to traditional open surgical techniques.
Stent Graft Outcomes in Dialysis Circuits: A Review of Clinical Trials and Literature
Authors: Pourmoussa Austin J. , Mahendra Ashwin M. , Peña Constantino S. , Powell Alex , Schiro Brian J. , Herrera Raul , Katzen Barry T. , Narayanan Govindarajan , Niekamp Andrew S. , Gandhi Ripal T. 
Published: February 2022

AbstractEnd-stage renal disease is a prevalent medical condition causing significant problems as the majority of patients are being treated with dialysis. While dialysis provides a means to compensate for the renal impairment, arteriovenous grafts and fistulas are often complicated by neointimal hyperplasia, loss of primary patency, and graft failure. Over the last decade, stent grafts have emerged as an alternative to balloon angioplasty and bare metal stents for revascularization in the event of arteriovenous graft occlusion or stenosis. Several randomized controlled trials have investigated the efficacy of stent grafts compared with balloon angioplasty for improving the function and durability of dialysis circuits. In this review, we present a comprehensive review of clinical trials. Stent grafts appear to offer increased primary patency over balloon angioplasty in the treatment of dialysis circuit stenosis. However, there is generally no significant difference between the two treatment modalities on other clinically relevant measures like complication rates and overall survival.
Effect of Menopausal Status on Chemotherapy-Induced Peripheral Neuropathy: Single-Institution Retrospective Audit
Authors: Singh Akshita , Nair Nita S. , Gupta Sudeep , Parmar Vani , Prabhu Aruna , Hawaldar Rohini , Badwe Rajendra A. 
Published: February 2022

Abstract
Introduction Paclitaxel can cause peripheral neuropathy in up to 60% of patients. Chemotherapy-induced peripheral neuropathy (CIPN) compromises quality of life and often leads to dose reduction or discontinuation of lifesaving chemotherapy. Preclinical models have suggested the possible neuroprotective effect of progesterone through remyelination and other mechanisms.
Objectives The aim of this study was to evaluate the incidence of CIPN for different menopausal status.
Materials and Methods We evaluated the effect of menopausal status, as a surrogate for circulating progesterone levels, on the risk of developing paclitaxel-induced peripheral neuropathy, in an audit of breast cancer patients. Data on CIPN (by clinical history and examination) and other variables were collected from the case charts of patients who had received paclitaxel-based chemotherapy for breast cancer at our institution.
Results Five hundred and fifty women were treated with either neoadjuvant or adjuvant paclitaxel in this period. Of these, 262 (47.6%) women were premenopausal, 49 (8.9%) were perimenopausal, and 239 (43.5%) were postmenopausal at the time of diagnosis. Forty-five (8.1%) women had pre-existing diabetes mellitus. Two hundred and fifty-six (82.31%) developed chemotherapy-induced amenorrhea (CIA).CIPN was seen in 32.7% of women who continued to be premenopausal after receiving chemotherapy and 62.3% of postmenopausal women. Thirty-five (77.8%) out of forty-five diabetic women developed CIPN. On a multivariate logistic regression model, pre-existing diabetes mellitus (risk ratio [RR] = 2.64, 95% confidence interval [CI]: 1.26–5.52, p = 0.009), postmenopausal (RR = 2.84, 95% CI = 1.48–5.45, p = 0.002), and CIA status (RR = 2.17, 95% CI = 1.14–4.12, p = 0.018) were significantly associated with the development of CIPN. Number of cycles did not appear to have an impact (p= 0.819).
Conclusions Postmenopausal status was independently associated with higher incidence of CIPN. One of the possible mechanisms could be lower circulating progesterone levels in these patients. A randomized controlled trial (CTRI/2015/11/006381) is ongoing to test this hypothesis.
Micro-Raman characterization of homo-epitaxial n doped GaN layers for vertical device applications
Authors: Eric N’Dohi Atse Julien , Sonneville Camille , Phung Luong Viet , Ngo Thi Huong , De Mierry Philippe , Frayssinet Eric , Maher Hassan , Tasselli Josiane , Isoird Karine , Morancho Frédéric , Cordier Yvon , Planson Dominique 
Published: February 2022

N-doped homo-epitaxial GaN samples grown on freestanding GaN substrates have been investigated by micro-Raman spectroscopy. Quantitative analysis of the E2h and the A1(LO) modes’ behavior has been performed while intentionally increasing the carrier density using silicon doping. We noticed that as the carrier concentration increases up to 1.8 × 1018 cm−3, the E2h mode remains unchanged. On the other hand, when the doping gets higher, the A1(LO) position shifts to a higher frequency range, its width becomes larger, and its intensity drastically diminishes. This change in the A1(LO) behavior is due to its interaction and its coupling with the free negative charge carriers. Furthermore, we calibrated the A1(LO) frequency position shift as a function of the n-carrier concentration. We found out that for low n doping, the change in the A1(LO) position can be considered as a linear variation while in the overall doping range, a sigmoid growth trend with a Boltzmann fit can be tentatively applied to describe the A1(LO) position shift. This calibration curve can also be used to describe the coupling strength between the carriers and the A1(LO) phonon. Eventually, this study shows that micro-Raman spectroscopy is a powerful non-destructive tool to probe the doping concentration and the crystalline quality of GaN material with a microscopic spatial resolution.