bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parallelism Between Sentence Structure and Nominal Phrases in Japanese: Evidence from Scrambled Instrumental and Locative Adverbial Phrases
Authors: Tamaoka Katsuo , Ito Takane , Mansbridge Michael P. 
Published: April 2022

AbstractThe present study investigated the canonical position of instrumental and locative adverbial phrases in both Japanese sentences and noun phrases to determine whether the canonical positions are parallel. A series of sentence/phrase decision tasks were used to compare sentences with different word-orders, including sentences with SAdvOV (S is subject phrase, Adv adverb, O object phrase and V verb), AdvSOV, SAdvOV and SOAdvV word orders. SAdvOV word order was found to be the most quickly processed, for both instrumental adverbial (Experiment 1) and locative adverbial phrases (Experiment 2). Thus, the canonical position for these adverbial phrases is identified as the position immediately preceding the object (Theme argument). This finding was replicated when the same experimental methods were applied to event-denoting noun phrases. Adverbial adjuncts in the initial position (AdvON, N is noun phrase) were processed more quickly and accurately than noun phrases with adverbial phrases in the second position (OAdvN), for both instrumental adverbial (Experiment 3) and locative adverbial phrases (Experiment 4). Therefore, the position immediately preceding the object is the canonical position for both instrumental and locative adverbial phrases in sentences and in noun phrases. In conclusion, this indicates that the base structure of a sentence is shared by its related noun phrase.
Minority and Majority Adolescents’ Attitudes toward Mutual Acculturation and its Association with Psychological Adjustment
Authors: Sidler Petra , Baysu Gülseli , Kassis Wassilis , Janousch Clarissa , Chouvati Raia , Govaris Christos , Graf Ulrike , Rietz Christian 
Published: April 2022

AbstractAlthough acculturation is considered a mutual process, no measure assesses attitudes toward mutual acculturation. Through a novel four-dimensional measurement, this study addresses this research gap by assessing attitudes toward minority and majority acculturation and its relation to psychological adjustment for immigrant-background minority and non-immigrant majority adolescents in public secondary schools in three European countries: in Germany (n = 346, 46% female,Mage = 12.78 years, range 11–16), Greece (n = 439, 56% female,Mage = 12.29 years, range 11–20), and Switzerland (n = 375, 47% female,Mage = 12.67 years, range 11–15). Latent profile analyses led to three distinct acculturation profiles in all three countries: strong and mild mutual integration profiles, where both migrant and majority students are expected to integrate, and a third profile assuming lower responsibility upon the majority. Additionally, those in the strong- and mild-integration profiles reported stronger psychological adjustment than those assuming lower responsibility upon the majority, which held for all students in Switzerland and mostly for those without a migration background in Germany. The findings demonstrate the importance of a mutual acculturation framework for future research. Moreover, as most adolescents fit in with one of the mutual integration patterns, findings stress that no matter their migration background, adolescents favor mutual integration including the expectation on schools to enhance intercultural contact.
Can Flip-Chart Assisted Maternal Education Improve Essential New Born Care Knowledge and Skills? A Randomized Controlled Trial
Authors: Eluri Swathi , Baliga B. Shantharam , Rao Suchetha S. , Vinayagamoorthy V. , Kamath Nutan 
Published: April 2022

Abstract
Background
Despite the implementation of essential newborn care (ENC) by the World Health Organization, knowledge gaps among postpartum women persist. Inappropriate breastfeeding practices and lack of knowledge regarding ENC among mothers has resulted in higher neonatal mortality.

Purpose
Our study focused on evaluating the effectiveness of flip-chart assisted postpartum maternal education in improving ENC knowledge and skills.

Material and Methods
A single blind parallel randomized controlled trial was carried out with 120 primigravidae. Participants were allocated to the intervention group (IG) or the control group (CG) by block randomization. A pretested validated questionnaire was administered to participants in both groups within 24 h post-delivery. Women in the IG were provided flip-chart assisted education regarding ENC approximately 24 h post-delivery. Women in both groups received verbal advice on ENC from the postnatal ward nurses, as per the existing hospital policy. ENC skills were observed in all participants in postnatal wards by independent observers. 6 months later, knowledge retention was assessed and analyzed in both groups.

Results
Antenatal education remained at 32% among all postnatal women. Postnatal flip-chart-assisted maternal education had a significant impact on ENC skills in the IG (p < 0.01) and precipitated higher knowledge scores at the end of 6 months (p < 0.01) in the IG.

Conclusion for Practice
Flip-chart assisted education soon after delivery had a sustained effect on ENC knowledge and practices that persisted for 6 months post-delivery.
Does corporate social responsibility impact equity risk? International evidence
Authors: Monti Alice , Pattitoni Pierpaolo , Petracci Barbara , Randl Otto 
Published: April 2022

AbstractBased on a large panel of listed firms from 52 countries in the period 2002–2020, we investigate the relationship between corporate social responsibility (CSR) and equity risk. We confirm previous evidence that higher CSR scores are related to lower risk measures, considering all types of risks: total, systematic, and idiosyncratic. Analyzing a large international sample allows us to investigate the role of country and company characteristics in the relationship between CSR scores and risk measures. The risk-reducing effect is more pronounced in weaker institutional environments. It is stronger in civil-law countries, in countries with low security regulation or disclosure requirement levels and where financial information is less widespread. Firms in high impact or high profile industries benefit more from CSR than firms in other industries as do firms that are not cross-listed. The financial crisis has increased the risk-reducing effect of CSR. The main results are confirmed in the COVID-19 period.
What is it like to be a chimpanzee?
Authors: Tomasello Michael 
Published: April 2022

AbstractChimpanzees and humans are close evolutionary relatives who behave in many of the same ways based on a similar type of agentive organization. To what degree do they experience the world in similar ways as well? Using contemporary research in evolutionarily biology and animal cognition, I explicitly compare the kinds of experience the two species of capable of having. I conclude that chimpanzees’ experience of the world, their experiential niche as I call it, is: (i) intentional in basically the same way as humans’; (ii) rational in the sense that it is self-critical and operates with logically structured causal and intentional inferences; but (iii) not normative at all in that it does not operate with “objective” evaluative standards. Scientific data do not answer philosophical questions, but they provide rich raw material for scientists and philosophers alike to reflect on and clarify fundamental psychological concepts.
A coupled hydro-mechanical model for subsurface erosion with analyses of soil piping and void formation
Authors: Scheperboer I. C. , Suiker A. S. J. , Bosco E. , Clemens F. H. L. R. 
Published: April 2022

AbstractA coupled hydro-mechanical erosion model is presented that is used for studying soil piping and erosion void formation under practical, in-situ conditions. The continuum model treats the soil as a two-phase porous medium composed of a solid phase and a liquid phase, and accounts for its elasto-plastic deformation behaviour caused by frictional sliding and granular compaction. The kinetic law characterizing the erosion process is assumed to have a similar form as the type of threshold law typically used in interfacial erosion models. The numerical implementation of the coupled hydro-mechanical model is based on an incremental-iterative, staggered update scheme. A one-dimensional poro-elastic benchmark problem is used to study the basic features of the hydro-mechanical erosion model and validate its numerical implementation. This problem is further used to reveal the interplay between soil erosion and soil consolidation processes that occur under transient hydro-mechanical conditions, thereby identifying characteristic time scales of these processes for a sandy material. Subsequently, two practical case studies are considered that relate to a sewer system embedded in a sandy soil structure. The first case study treats soil piping caused by suffusion near a sewer system subjected to natural ground water flow, and the second case study considers the formation of a suffosion erosion void under strong ground water flow near a defect sewer pipe. The effects on the erosion profile and the soil deformation behaviour by plasticity phenomena are elucidated by comparing the computational results to those obtained by modelling the constitutive behaviour of the granular material as elastic. The results of this comparison study point out the importance of including an advanced elasto-plastic soil model in the numerical simulation of erosion-driven ground surface deformations and the consequent failure behaviour. The numerical analyses further illustrate that the model realistically predicts the size, location, and characteristic time scale of the generated soil piping and void erosion profiles. Hence, the modelling results may support the early detection of in-situ subsurface erosion phenomena from recorded ground surface deformations. Additionally, the computed erosion profiles may serve as input for a detailed analysis of the local, residual bearing capacity and stress redistribution of buried concrete pipe systems.
The Role of Outward FDI in Creating Korean Global Factories
Authors: Buckley Peter J. , Driffield Nigel , Kim Jae-Yeon 
Published: April 2022

AbstractThis study examines Korean foreign direct investment (FDI) in the context of the organization and development of local firms into global factories. Specifically, we explore the relationship between FDI decisions and the nature of Korea’s imported and exported goods. We argue that the global factory approach explains the mechanisms by which FDI can lead to technological upgrading. We employ a unique dataset that incorporates information on FDI motive from South Korea, as well as the unit value of traded goods within sectors. Our findings indicate that FDI location and motive vary by trade destinations and trade unit prices; something that has not received attention in existing literature.
Improved guidelines for any-aged forestry
Authors: Pukkala Timo 
Published: April 2022

AbstractAny-aged forest management (AAF) is a means to reduce clear-felling without compromising profitability or timber production. The concept of AAF is to choose between clear-felling or thinning one harvest at a time based on what is better at that time in terms of the management objectives for the forest. No permanent choice is made between rotation forest management (RFM) and continuous cover forestry (CCF). Optimized AAF is never less profitable than RFM or CCF because all cutting types of both RMF and CCF are also allowed in AAF. This study developed a new set of guidelines for managing boreal forest stands under AAF when the forest landowner maximizes economic profitability. The first part of the guidelines indicates whether the stand should be cut or left to grow. This advice is based on stand basal area, mean tree diameter, minimum allowable post-thinning basal area, site productivity, and discount rate. If the optimal decision is harvesting, the second instruction determines whether the harvest should be clear-felling or thinning. In the case of thinning, the remaining two steps determine the optimal harvest rate in different diameter classes. The guidelines were developed using two different modeling approaches, regression analysis, and optimization, and applied to two Finnish forest holdings, one representing the southern boreal zone and the other the northern parts of the boreal zone. The results show that AAF improves profitability compared to current Finnish management instructions for RFM. The use of clear-felling also decreased the lower the minimum acceptable post-thinning basal area of the stand.
Impact of the temporary closure of a major bridge on local air quality in two large German cities: an accountability study
Authors: Brach B. , Pikmann J. , Fachinger F. , Kemmerer P. , Büchler B. , Singer S. , König J. , Blettner M. , Drewnick F. , Gianicolo Emilio A. L. 
Published: April 2022

AbstractDespite recent achievements in reducing the contribution of road traffic to air pollution, agreed pollutant standards are exceeded frequently in large parts of Europe. Previous studies assessed the effectiveness of traffic interventions in improving local air quality. However, little research exists on the effect of closures of short road sections over longer periods. The multi-week maintenances on the Theodor Heuss Bridge, the main connection over the river Rhine between the German cities Mainz and Wiesbaden, offered the opportunity to investigate its effect on local air pollution. We measured ambient concentrations of major air pollutants and meteorological parameters at the Theodor Heuss Bridge before, during, and after its closure on 800 m in early 2020. We carried out time-series and closure-dependent evaluations of pollutant concentrations at the bridge accounting for wind direction. Furthermore, we performed regression analyses accounting for wind speed additionally. We compared the results with data from surrounding monitoring stations. We recorded higher concentrations at the Theodor Heuss Bridge compared to outside the closure, especially for particulate matter, nitric oxide, and black carbon. Only with wind from specific directions, we could detect reductions of concentrations during the closure for many pollutants as nitrogen dioxide (− 9.8%; 95% confidence interval: − 10.8– − 8.7%), but not for particulate matter. Since we found similar meteorology-dependent pollution reductions during the closure at both the bridge and the surrounding monitoring stations, we assume that regional meteorological factors overlaid a potential closure-related effect on local air quality. These factors must be accounted for in accountability studies on interventions focusing on short roads.
An Update on Refractory Hypertension
Authors: Matanes Faris , Khan M. Bilal , Siddiqui Mohammed , Dudenbostel Tanja , Calhoun David , Oparil Suzanne 
Published: April 2022

Abstract
Purpose of Review
To update on definition, diagnosis, prevalence, patient characteristics, pathophysiology, and treatment of refractory hypertension (RfHTN).

Recent Findings
Refractory hypertension (RfHTN) is defined as blood pressure (BP) that is uncontrolled despite using ≥ 5 antihypertensive medications of different classes, including a long-acting thiazide diuretic and a mineralocorticoid receptor antagonist (MRA) at maximal or maximally tolerated doses. This new phenotype is different from resistant hypertension (RHTN), defined as BP that is uncontrolled despite using ≥ 3 medications, commonly a long-acting calcium channel blocker (CCB), a blocker of the renin-angiotensin system (angiotensin-converting enzyme [ACE] inhibitor or angiotensin receptor blocker [ARB]), and a diuretic. The RHTN phenotype includes controlled RHTN, BP that is controlled on 4 or more medications. RfHTN is largely attributable to increased sympathetic activity, unlike RHTN, which is mainly due to increased intravascular fluid volume frequently caused by hyperaldosteronism and chronic excessive sodium ingestion. Compared to those with controlled RHTN, patients with RfHTN have a higher prevalence of target organ damage and do not have elevated aldosterone levels. Ongoing clinical trials are assessing the safety and efficacy of using devices to aid with BP control in patients with RfHTN.

Summary
RfHTN is a separate entity from RHTN and is generally attributable to increased sympathetic activity.
Assessing Ecosystem Services Provision as a Support for Metropolitan Green Infrastructure Planning: the Case of Three Spanish Metropolitan Areas
Authors: Santiago-Ramos Jesús , Hurtado-Rodríguez Claudia 
Published: April 2022

AbstractThe main purpose of this paper is to develop a systematic, spatially explicit approach to the analysis of the ecosystem services provided by the metropolitan landscape that can act as a support for green infrastructure planning. To achieve this, we have proposed a set of indicators to assess and map nine ecosystem services—including regulating, provisioning, habitat and cultural services. This methodology has been applied to three case studies in the south of Spain: the metropolitan areas of Seville, Malaga-Marbella and Cordoba. Despite the geographical proximity of these areas to one another, the indicators show that there are significant differences in their potentialities and available resources to form a multipurpose green space system. The results suggest that further reflection is needed on how the concept of green infrastructure can be applied to metropolitan areas, especially in the Mediterranean region and other similar geographical contexts. Instead of understanding green infrastructure strictly in terms of a network of interconnected green spaces and natural areas, planning initiatives should assign a more important role to the landscape matrix and, in particular, to the multifunctional cultivated space on the urban fringe. In addition, more thought needs to be given to how to create functional green corridors in the metropolitan landscape for public use and habitat conservation. From the perspective of spatial planning, the methodology proposed has been demonstrated to be a useful tool to identify key spaces for the provision of ecosystem services.
Sarcomas of fat and bone: a case report
Authors: Honnicke Miriam Beate , Tharun Lars , Sieren Malte Maria , Barkhausen Jörg 
Published: April 2022

AbstractOsteosarcomas are the most common primary malignant bone tumors and are classified by the WHO into several intramedullary and surface subtypes. One of these is the rare parosteal osteosarcoma. Liposarcomas are the second most common soft tissue sarcoma and are classified into several types ranging from intermediate to high grade tumors. In one of our recent patients we found an unusual combination of a parosteal osteosarcoma and a large fatty component, which fluorescence-in-situ-hybridization revealed as liposarcoma. Radiologists, pathologists, and surgeons should consider the possibility of bone and soft tissue malignancies consisting of different components, as this may be of paramount importance for oncologically complete resection.
Circulating concentrations of free triiodothyronine are associated with central adiposity and cardiometabolic risk factors in young euthyroid adults
Authors: Merchan-Ramirez Elisa , Sanchez-Delgado Guillermo , Arrizabalaga-Arriazu Cristina , Acosta Francisco M , Arias-Tellez Maria Jose , Muñoz-Torres Manuel , Garcia-Lario Jose V , Llamas-Elvira Jose M , Ruiz Jonatan R 
Published: April 2022

AbstractThyroid dysfunction is associated with classic cardiometabolic risk factors in humans. However, this relationship remains unclear in young euthyroid adults. The present work examines the associations of circulating thyroid hormones (THs) and thyroid-stimulating hormone (TSH) concentrations with body composition and cardiometabolic risk factors in young euthyroid adults. A total of 106 sedentary, euthyroid adults (72 women; 22 ± 2 years old) participated in this cross-sectional study. THs and TSH serum concentrations were determined in fasting conditions (6 h). Body composition (fat mass (FM), lean mass (LM), and visceral adipose tissue (VAT)) was determined by dual-energy X-ray absorptiometry, anthropometric parameters (weight, height, and waist circumference) were measured, and neck adipose tissue mass was quantified through computed tomography (CT) scanning. Cardiometabolic risk factors including fasting glucose and lipid metabolism markers, hepatic phosphatase and transaminases, and blood pressure were also assessed. Free triiodothyronine (FT3) concentration was positively associated with body mass index, LM, VAT, and waist circumference (all P ≤ 0.038). FT3 was also associated with glucose, insulin, HOMA-IR, fatty liver index, and blood pressure (all P < 0.024). All the associations were attenuated when adjusting for sex. In contrast, we found no associations of TSH or free thyroxine with any body composition parameter or cardiometabolic risk factors. In conclusion, FT3 is associated with central adiposity and cardiometabolic risk factors including insulin resistance, fatty liver index, and mean, systolic and diastolic blood pressure in young euthyroid adults. ClinicalTrials.gov identifier: NCT02365129.
Targeting papain-like protease for broad-spectrum coronavirus inhibition
Authors: Yuan Shuofeng , Gao Xiaopan , Tang Kaiming , Cai Jian-Piao , Hu Menglong , Luo Peng , Wen Lei , Ye Zi-Wei , Luo Cuiting , Tsang Jessica Oi-Ling , Chan Chris Chun-Yiu , Huang Yaoqiang , Cao Jianli , Liang Ronghui , Qin Zhenzhi , Qin Bo , Yin Feifei , Chu Hin , Jin Dong-Yan , Sun Ren , Chan Jasper Fuk-Woo , Cui Sheng , Yuen Kwok-Yung 
Published: April 2022

AbstractThe emergence of SARS-CoV-2 variants of concern and repeated outbreaks of coronavirus epidemics in the past two decades emphasize the need for next-generation pan-coronaviral therapeutics. Drugging the multi-functional papain-like protease (PLpro) domain of the viral nsp3 holds promise. However, none of the known coronavirus PLpro inhibitors has been shown to be in vivo active. Herein, we screened a structurally diverse library of 50,080 compounds for potential coronavirus PLpro inhibitors and identified a noncovalent lead inhibitor F0213 that has broad-spectrum anti-coronaviral activity, including against the Sarbecoviruses (SARS-CoV-1 and SARS-CoV-2), Merbecovirus (MERS-CoV), as well as the Alphacoronavirus (hCoV-229E and hCoV-OC43). Importantly, F0213 confers protection in both SARS-CoV-2-infected hamsters and MERS-CoV-infected human DPP4-knockin mice. F0213 possesses a dual therapeutic functionality that suppresses coronavirus replication via blocking viral polyprotein cleavage, as well as promoting antiviral immunity by antagonizing the PLpro deubiquitinase activity. Despite the significant difference of substrate recognition, mode of inhibition studies suggest that F0213 is a competitive inhibitor against SARS2-PLpro via binding with the 157K amino acid residue, whereas an allosteric inhibitor of MERS-PLpro interacting with its 271E position. Our proof-of-concept findings demonstrated that PLpro is a valid target for the development of broad-spectrum anti-coronavirus agents. The orally administered F0213 may serve as a promising lead compound for combating the ongoing COVID-19 pandemic and future coronavirus outbreaks.