bluuebunny/crossref_metadata_2025_split huggingface dataset:
A gestão de projetos como ferramenta para administração pública eficiente: estudo de caso da Fundação Cecierj
Authors: Dahmouche Mônica Santos , Bernstein Marianna Augusta Ferrari do Outeiro , Fernandes Michelle Casal , Santos Beatriz Ferreira Oliveira 
Published: July 2022

Neste artigo apresentamos e discutimos a metodologia de gestão de projeto no âmbito da administração pública, além de usarmos a sua aplicação na Fundação Cecierj como um estudo de caso. Um benchmark cuidadoso acerca do uso da metodologia de gestão de projetos no âmbito de todas as esferas da administração pública é apresentado com as particularidades de cada caso. Descrevemos a pesquisa situacional inédita realizada junto aos servidores da Fundação Cecierj, com adesão da maioria. Os resultados mostram que o corpo técnico da instituição, a conhece bem e demanda por ações de planejamento e transparência que possam contribuir para a melhoria da governança institucional. As conclusões indicam que os servidores são receptivos à gestão amparada em um Escritório de Gestão de Projetos. Embora o escritório ainda não tenha sido implementado, já é possível observar algumas iniciativas da alta gestão que vão ao encontro das demandas do corpo técnico.
A lei 12.858 e a aplicação de royalties em saúde nos municípios fluminenses produtores de petróleo no regime da partilha
Authors: Smiderle Carlos Gustavo Sarmet Moreira , Ney Marlon Gomes 
Published: July 2022

O objetivo desse artigo é identificar e analisar os primeiros efeitos da vinculação legal à saúde (Lei 12.858/2013) de parte dos royalties e participações especiais gerados por campos de produção amparados por contratos posteriores a 03 de dezembro de 2012. Para tanto, foram levantados todos os campos enquadráveis nessa normativa e identificados os municípios com eles confrontantes, os quais concentram a maior parte da fatia de royalties geradas por esses campos e distribuídas à instância municipal. Em seguida selecionamos os quatro municípios fluminenses incluídos nessa lista e sujeitos à fiscalização do Tribunal de Contas do Estado do Rio de Janeiro (TCE-RJ), a saber, Araruama (RJ), Arraial do Cabo (RJ), Quissamã (RJ) e Saquarema (RJ). Não consideramos a capital do estado por estar sujeita a seu próprio tribunal de contas municipal e porque os valores envolvidos são insignificantes frente a seu orçamento. Os resultados apontam que, como a proporção das rendas petrolíferas geradas por campos contratados a partir de dezembro de 2012 na RCL ainda é pequena, a Lei 12.858/2013 não chegou a gerar, no período de 2015 a 2020, um aumento da participação dos gastos com saúde no total das despesas liquidadas.
Medida de la precariedad laboral en Centroamérica: propiedades psicométricas en base a la II Encuesta Centroamericana de Condiciones de Trabajo y Salud
Authors: Palma-Vasquez Claudia , Vives Alejandra , Gimeno Ruiz de Porras David , Rojas-Garbanzo Marianela , G. Benavides Fernando 
Published: July 2022

Objetivo: Establecer las propiedades psicométricas de una medida de Precariedad Laboral (PL) en seis países centroamericanos de habla española (Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua y Panamá) mediante un conjunto de ítems incluidos en la II Encuesta Centroamericana de Condiciones de Trabajo y Salud (II ECCTS) de 2018 que se correspondían con ítems de la Escala de Precariedad Laboral (EPRES).
Método: A partir de una muestra de 3.782 personas asalariadas de 18 años o más, formales e informales, en la II ECCTS, se construyó una medida de PL de 10 ítems representando cuatro dimensiones: temporalidad, salario, derechos y ejercicio de derechos.
Resultados: La muestra estuvo compuesta en su mayoría por hombres, con contrato permanente, con antigüedad laboral de entre 2 a 5 años, un salario entre 301 a 500 dólares, que reportaban tener derechos laborales y ejercerlos. La estructura factorial no pudo ser comprobada. Sin embargo, nueve de los diez ítems arrojaron alta carga factorial en sus dimensiones correspondientes. Se observó una alta aceptabilidad de medida de PL y los coeficientes de Alpha de Cronbach de las cuatro dimensiones fueron >0,59 excepto para temporalidad (0,30). La confiabilidad de la escala fue de 0,68 y los patrones de PL en mujeres, jóvenes, temporales y países con menores ingresos fueron los esperados.

Conclusiones: La medida de PL construida a partir de ítems disponibles de la escala EPRES en el cuestionario de la II ECCTS evidencia propiedades psicométricas aceptables para aproximarnos a la cuantificación epidemiológica de la precariedad laboral en Centroamérica.
Real Time Skin Color Detection Based on Adaptive HSV Thresholding
Authors: Moumene Mohammed Elamine , Benkedadra Khadidja , Berras Fatima Zohra 
Published: July 2022

The detection of human skin color has been studied extensively during the past two decades. It is an essential task for various computer vision applications such as biometric authentication, face/hands tracking and gesture analysis. New machine learning methods are effective for skin color detection. However, they are not suitable for real time applications since they are computationally heavy. A lightweight approach for skin color detection consists of using segmentation rules extracted by an investigation on skin color distribution. The kin appearance varies with diversity of image types, acquisition parameters and scene illumination. There are no general segmentation rules that provide effective skin segmentation for different scene conditions. In this paper we present a real-time skin color detector which adapts itself according to tracked human parts. First, initial thresholds are calculated using two popular skin datasets. Those thresholds can also be calculated quickly using small training sets. The proposed skin color detector showed comparable skin segmentation to DeepLabV3++ application and an improvement in term of F1 measure when compared to methods that relies on static rules.
More than 6  kW near single-mode fiber amplifier based on a bidirectional tandem pumping scheme
Authors: Li Ruixian , Wu Hanshuo , Xiao Hu , Leng Jinyong , Huang Liangjin , Zhou Pu 
Published: July 2022

We demonstrate the first all-fiber monolithic bidirectional tandem pumping amplifier, to the best of our knowledge, based on a 30/250 µm conventional ytterbium-doped double-clad fiber. By optimizing the bidirectional pumping power distribution, an output power of 6.22 kW is obtained with near single-mode beam quality (

M

2

=
1.53

), and no transverse mode instability is observed. This work could provide an excellent reference for high-power, higher-brightness fiber lasers.
Cardiometabolic outcomes up to 12 months after COVID-19 infection. A matched cohort study in the UK
Authors: Rezel-Potts Emma , Douiri Abdel , Sun Xiaohui , Chowienczyk Phillip J. , Shah Ajay M. , Gulliford Martin C. 
Published: July 2022

BackgroundAcute Coronavirus Disease 2019 (COVID-19) has been associated with new-onset cardiovascular disease (CVD) and diabetes mellitus (DM), but it is not known whether COVID-19 has long-term impacts on cardiometabolic outcomes. This study aimed to determine whether the incidence of new DM and CVDs are increased over 12 months after COVID-19 compared with matched controls.Methods and findingsWe conducted a cohort study from 2020 to 2021 analysing electronic records for 1,356 United Kingdom family practices with a population of 13.4 million. Participants were 428,650 COVID-19 patients without DM or CVD who were individually matched with 428,650 control patients on age, sex, and family practice and followed up to January 2022. Outcomes were incidence of DM and CVD. A difference-in-difference analysis estimated the net effect of COVID-19 allowing for baseline differences, age, ethnicity, smoking, body mass index (BMI), systolic blood pressure, Charlson score, index month, and matched set. Follow-up time was divided into 4 weeks from index date (“acute COVID-19”), 5 to 12 weeks from index date (“post-acute COVID-19”), and 13 to 52 weeks from index date (“long COVID-19”). Net incidence of DM increased in the first 4 weeks after COVID-19 (adjusted rate ratio, RR 1.81, 95% confidence interval (CI) 1.51 to 2.19) and remained elevated from 5 to 12 weeks (RR 1.27, 1.11 to 1.46) but not from 13 to 52 weeks overall (1.07, 0.99 to 1.16). Acute COVID-19 was associated with net increased CVD incidence (5.82, 4.82 to 7.03) including pulmonary embolism (RR 11.51, 7.07 to 18.73), atrial arrythmias (6.44, 4.17 to 9.96), and venous thromboses (5.43, 3.27 to 9.01). CVD incidence declined from 5 to 12 weeks (RR 1.49, 1.28 to 1.73) and showed a net decrease from 13 to 52 weeks (0.80, 0.73 to 0.88). The analyses were based on health records data and participants’ exposure and outcome status might have been misclassified.ConclusionsIn this study, we found that CVD was increased early after COVID-19 mainly from pulmonary embolism, atrial arrhythmias, and venous thromboses. DM incidence remained elevated for at least 12 weeks following COVID-19 before declining. People without preexisting CVD or DM who suffer from COVID-19 do not appear to have a long-term increase in incidence of these conditions.
Quantitative longitudinal T2* mapping for assessing placental function and association with adverse pregnancy outcomes across gestation
Authors: Schabel Matthias C. , Roberts Victoria H. J. , Gibbins Karen J. , Rincon Monica , Gaffney Jessica E. , Streblow Aaron D. , Wright Adam M. , Lo Jamie O. , Park Byung , Kroenke Christopher D. , Szczotka Kathryn , Blue Nathan R. , Page Jessica M. , Harvey Kathy , Varner Michael W. , Silver Robert M. , Frias Antonio E. 
Published: July 2022

Existing methods for evaluating in vivo placental function fail to reliably detect pregnancies at-risk for adverse outcomes prior to maternal and/or fetal morbidity. Here we report the results of a prospective dual-site longitudinal clinical study of quantitative placental T2* as measured by blood oxygen-level dependent magnetic resonance imaging (BOLD-MRI). The objectives of this study were: 1) to quantify placental T2* at multiple time points across gestation, and its consistency across sites, and 2) to investigate the association between placental T2* and adverse outcomes. 797 successful imaging studies, at up to three time points between 11 and 38 weeks of gestation, were completed in 316 pregnancies. Outcomes were stratified into three groups: (UN) uncomplicated/normal pregnancy, (PA) primary adverse pregnancy, which included hypertensive disorders of pregnancy, birthweight <5th percentile, and/or stillbirth or fetal death, and (SA) secondary abnormal pregnancy, which included abnormal prenatal conditions not included in the PA group such as spontaneous preterm birth or fetal anomalies. Of the 316 pregnancies, 198 (62.6%) were UN, 70 (22.2%) PA, and 48 (15.2%) SA outcomes. We found that the evolution of placental T2* across gestation was well described by a sigmoid model, with T2* decreasing continuously from a high plateau level early in gestation, through an inflection point around 30 weeks, and finally approaching a second, lower plateau in late gestation. Model regression revealed significantly lower T2* in the PA group than in UN pregnancies starting at 15 weeks and continuing through 33 weeks. T2* percentiles were computed for individual scans relative to UN group regression, and z-scores and receiver operating characteristic (ROC) curves calculated for association of T2* with pregnancy outcome. Overall, differences between UN and PA groups were statistically significant across gestation, with large effect sizes in mid- and late- pregnancy. The area under the curve (AUC) for placental T2* percentile and PA pregnancy outcome was 0.71, with the strongest predictive power (AUC of 0.76) at the mid-gestation time period (20–30 weeks). Our data demonstrate that placental T2* measurements are strongly associated with pregnancy outcomes often attributed to placental insufficiency.
Trial registration: ClinicalTrials.gov: NCT02749851.
Albadejo García, M. D. (2020). Aprovechamiento didáctico de textos narrativos en el aula de español como lengua extranjera. Editorial Universidad de Jaén
Authors: Gimeno Gimeno Neus 
Published: July 2022

Reseña del libro: Albadejo García, Mª Dolores (2020). Aprovechamiento didáctico de textos narrativos en el aula de español como lengua extranjera. Jaén: Editorial Universidad de Jaén. (272 páginas, ISBN 978-84-9159-349-2).
Role of insulin resistance and the gut microbiome on urine oxalate excretion in ob/ob mice
Authors: Xiang Hong , Chen Haoqing , Liu Yuanyuan , Dodd Dylan , Pao Alan C. 
Published: July 2022

AbstractOb/ob mice have recently emerged as a model for obesity‐related hyperoxaluria as they are obese and excrete more urine oxalate compared to wild type mice. Ob/ob mice are deficient of leptin and develop obesity with hyperphagia and hyperinsulinemia. We hypothesized that insulin resistance and the gut microbiome contribute to hyperoxaluria in ob/ob mice. We developed a new liquid chromatography–mass spectrometry assay for urine oxalate and first compared urine oxalate excretion in ob/ob mice before and after ablation of intestinal bacteria with a standard antibiotic cocktail. We then compared urine oxalate excretion in ob/ob mice before and after leptin replacement or pioglitazone treatment, two maneuvers that reduce insulin resistance in ob/ob mice. Ob/ob mice excreted more oxalate into the urine in a 24‐h period compared to wild type mice, but antibiotic, leptin, or pioglitazone treatment did not change urine oxalate excretion in ob/ob mice. Unexpectedly, we found that when food intake was carefully matched between ob/ob and wild type mice, the amount of 24‐h urine oxalate excretion did not differ between the two mouse strains, suggesting that ob/ob mice excrete more urine oxalate because of hyperphagia. Since the level of urine oxalate excretion in wild type mice in our study was higher than those reported in prior studies, future work will be needed to standardize the measurement of urine oxalate and to define the range of urine oxalate excretion in wild type mice so that accurate and valid comparisons can be made between wild type mice and ob/ob mice or other mouse models.
Robo-Advice as a Digital Finance Platform
Authors: Zunzunegui Fernando 
Published: July 2022

Abstract

This paper is about automated financial advice, known as Robo-Advice. Its origin and development are analysed as a prominent Fintech activity. After tackling its legal nature as a service platform and showing how it is different from traditional human advice, its legal framework is addressed, particularly in the European Union, to conclude with some legislative policy proposalsto regulate it as a digital finance platform.
Enhancement of visual perception by combining transcranial electrical stimulation and visual perceptual training
Authors: He Qing , Yang Xin-Yue , Zhao Daiqing , Fang Fang 
Published: July 2022

Abstract
The visual system remains highly malleable even after its maturity or impairment. Our visual function can be enhanced through many ways, such as transcranial electrical stimulation (tES) and visual perceptual learning (VPL). TES can change visual function rapidly, but its modulation effect is short-lived and unstable. By contrast, VPL can lead to a substantial and long-lasting improvement in visual function, but extensive training is typically required. Theoretically, visual function could be further improved in a shorter time frame by combining tES and VPL than by solely using tES or VPL. Vision enhancement by combining these two methods concurrently is both theoretically and practically significant. In this review, we firstly introduced the basic concept and possible mechanisms of VPL and tES; then we reviewed the current research progress of visual enhancement using the combination of two methods in both general and clinical population; finally, we discussed the limitations and future directions in this field. Our review provides a guide for future research and application of vision enhancement and restoration by combining VPL and tES.
Copper ternary oxides as photocathodes for solar-driven CO2reduction
Authors: Gonzaga Ian Lorenzo E. , Mercado Candy C. 
Published: July 2022

AbstractThe sun’s energy, though free and virtually limitless, is a largely unexploited resource, as its conversion into a storable form presents several technological challenges. A promising way of capturing and storing solar energy is in the form of “solar fuels,” in a process termed artificial photosynthesis. In a photoelectrochemical (PEC) system, the reduction of CO2to carbon-based fuels is driven on the surface of an illuminated semiconductor electrode. Through the decades, many different classes of semiconducting materials have been studied for this purpose, to varying successes. Because of their cheap and abundant nature, semiconducting transition metal oxides are good candidates to realize this technology in an economic scale and have thus attracted considerable research attention. In this review article, the progress achieved with a specific class of metal oxides, namely, the copper ternary oxides such as copper iron oxide and copper bismuth oxide, for PEC CO2reduction is examined. Although there have been significant advances in terms of strategies to improve the efficiency and stability of these materials, further studies are warranted to address the many challenges to PEC CO2reduction and solar fuel production.
Was bei Vereinsbeteiligungen beharrlich übersehen wird
Authors: Beuthien Volker 
Published: July 2022

Zusammenfassung

In Frage steht, ob und inwieweit sich ein eingetragener Verein an erwerbswirtschaftlich tätigen Gesellschaft beteiligen darf, ohne schon dadurch seinen nichtwirtschaftlichen Charakter zu verlieren. Anzuknüpfen ist dabei an die Regel, dass sich ein nichtwirtschaftlicher Verein die für die Erreichung seines Idealzwecks erforderlichen Mittel nicht nur durch Beiträge und Umlagen, sondern auch dadurch verschaffen kann, dass er ein Nebengewerbe betreibt oder einen Zweckausführungsbetrieb unterhält (sog. Kostendeckungsprivileg).
Cortisol-producing adenoma-related somatic mutations in unilateral primary aldosteronism with concurrent autonomous cortisol secretion: their prevalence and clinical characteristics
Authors: Wu Wan-Chen , Peng Kang-Yung , Lu Jin-Ying , Chan Chieh-Kai , Wang Chih-Yuan , Tseng Fen-Yu , Yang Wei-Shiung , Lin Yen-Hung , Lin Po-Chih , Chen Ting-Chu , Huang Kuo-How , Chueh Jeff S , Wu Vin-Cent 
Published: July 2022

Abstract

Objective
Concurrent autonomous cortisol secretion (ACS) in patients with primary aldosteronism (PA) is being reported more frequently. Several somatic mutations including PRKACA, GNAS, and CTNNB1 were identified in cortisol-producing adenomas (CPAs). The presence of these mutations in unilateral PA (uPA) patients concurrent with ACS (uPA/ACS) is not well known. This study aimed to investigate the prevalence of these mutations and their clinical vs pathological characteristics in uPA/ACS.

Design
This is a retrospective cohort study.

Methods
Totally 98 uPA patients from the Taiwan Primary Aldosteronism Investigation registry having overnight 1-mg dexamethasone suppression test (DST) and adrenalectomy from 2016 to 2018 were enrolled. Their adrenal tumors were tested for PRKACA, GNAS, and CTNNB1 mutations.

Results
11 patients had CPA-related mutations (7 PRKACA and 4 GNAS). The patients carrying these mutations had higher post-DST cortisol (5.6 vs 2.6 μg/dL, P = 0.003) and larger adenoma (2.2 ± 0.3 vs 1.9 ± 0.7 cm, P = 0.025). Adenomas with these mutations had a higher prevalence of non-classical uPA (72.7% vs 26.3%, P = 0.014). Numerically, slightly more complete clinical success of uPA patients with these mutations was noticed after adrenalectomy, although it was statistically non-significant. Post-DST cortisol levels, adenoma size &gt;1.9 cm, and the interaction of adenoma size &gt;1.9 cm with potassium level were found to be associated with the presence of these mutations.

Conclusion
Our study showed that CPA-related mutations were detected in 36.7% of uPA/ACS adenomas. The presence of these mutations was associated with higher post-DST cortisol levels, larger adenoma sizes, and a high percentage of non-classical uPA. However, these mutations did not significantly affect the clinical and biochemical outcomes after adrenalectomy of uPA/ACS patients but they showed a better trend.
Design and Validation of a Self-care Evaluation Instrument to Prevent Diabetic Foot
Authors: Herrera Guerra Eugenia del Pilar , Bautista Arellanos Lili Rosa 
Published: July 2022

Objective. This work sought to design and validate a self-care instrument to prevent diabetic foot in Colombian adults with diabetes.
Methods. Psychometric study in which an instrument was designed to measure self-care to prevent diabetic foot according to the Medium Range Theory of Self-care in chronic diseases. With a sample of 230 people with type-2 diabetes, construct validity was determined through exploratory and confirmatory factor analysis. Internal consistency was calculated with Cronbach's alpha coefficient.
Results. Favorable evidence of construct validity was obtained with a model consisting of three scales: self-care maintenance with a three-factor structure (accumulated variance 43%), α = 0.7, with good fit (????2= 64.698, p = 0.001; RMSEA = 0.066; RMSSR = 0.071; CFI = 0.936, NNFI = 0.910). Monitoring of self-care with presence of symptoms a two-factor structure was found, α = 0.950, with good fit (????2 = 266.837, p = 0.000; RMSEA = 0.321; RMSSR = 0.057; CFI = 0.848; NNFI = 0.789); and without symptoms, a single-factor structure (cumulative variance 84%), α = 0.9, acceptable fit (????2= 377.327, p < 0.001; RMSEA = 0.355; RMSSR = 0.073; CFI = 0.832; NNFI = 0.764). And self-care management with two-factor structure (cumulative variance 53.7%) α = 0.7, with good fit (????2 = 14.317, p = 0.014; RMSEA = 0.144; RMSSR = 0.063; CFI = 0.905; NNFI = 0.809).
Conclusions. The resulting instrument has adequate psychometric properties, consistent with the theoretical model of self-care in chronic diseases. Its use is recommended to evaluate self-care to prevent diabetic foot in populations similar to the study population.
Role of immunohistochemical markers in breast carcinoma and other breast pathologies: A review with a note on recent update
Authors: Roy Asitava Deb , Roy Ritu , Bhattacharyya Kali Sankar 
Published: July 2022

Breast cancer is the most common cause of malignancy worldwide in women & second most common cause of death among them. Higher number of cases have been observed from more developed regions than in less developed. In India age adjusted incidence rate of breast cancer is 2.8/100000 than United Kingdom (95/100000).Breast specimens for histopathological evaluation are one of the most common surgical pathology specimens encountered by a surgical pathologist. In regular breast pathology, immunohistochemistry is a useful tool for both diagnostic and prognostic purposes. Although, most breast lesions may be diagnosed using routine hematoxylin and eosin sections; but, in a few situations, such as morphologically equivocal instances or metastatic cancers of unknown source, immunohistochemistry can help to make a more accurate diagnosis.This review will focus on diagnostic immunomarkers. However, the main goal of this review is to assess the diagnostic value of the most commonly investigated immunomarkers in the field of breast pathology by a review of the literature utilising the PubMed (US National Library of Medicine, Bethesda, Maryland) database of indexed publications from 1976 to 2022.