bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pain Relief and Safety of Microwave Ablation Combined with Percutaneous Vertebroplasty for Vertebral Metastasis: A Pilot Study
Authors: Hu Ting-Ye , Zhang Gan , Ye Hong , An Cheng-Ling , Wang Kai , Xia Lei , Zhou Xiao-Xing , Zhang Shan-Shan , Lu Yu-He 
Published: December 2022

Abstract
Background We investigate the pain relief and safety of microwave ablation (MWA) combined with percutaneous vertebroplasty (PVP) in the treatment of metastatic vertebral tumors.
Methods This prospective pilot study enrolled patients with metastatic vertebral tumors treated between January 2018 and October 2019. The participants were randomized to the PVP and MWA + PVP groups. Clinical parameters, pain visual analog scale (VAS), analgesic use scores (AUS), and quality-of-life score (QLS) were compared between groups.
Results Sixty-seven participants were enrolled (PVP: n = 35; MWA + PVP: n = 32). There were no differences in bone cement injection volume, extravasation, and X-ray exposure time between the two groups (p > 0.05), but treatment costs were higher for the MWA + PVP group (26,418 ± 194 vs. 15,606 ± 148 yuan; p < 0.05). There were no significant improvements in VAS from baseline to 24 hours, 72 hours, 7 days, 1 month, and 3 months in the two groups (p > 0.05); at 6 and 12 months after the operation, the improvement from baseline was significant in the two groups (p < 0.05). The VAS was lower at 6 months (2.7 ± 0.7 vs. 3.2 ± 0.7) and 12 months (3.5 ± 0.8 vs. 4.0 ± 0.7) in the MWA + PVP group (both p < 0.01 vs. PVP). The AUS and QLS were improved with PVP at 6 and 12 months (p < 0.05) and with MWA + PVP at 12 months (p < 0.05). The AUS was lower at 6 and 12 months in the MWA + PVP group (p < 0.05 vs. PVP).
Conclusion MWA combined with PVP might be a safe and effective palliative treatment for pain from metastatic vertebral tumors.
Case Report of Undifferentiated Hepatic Embryonal Sarcoma with Mesenchymal Hamartoma: A Rare Entity
Authors: Jacob Dhanya , Pratap Thara , Yadav Abhishek , Jalal Muhammed Jasim Abdul , Mahadevan Pushpa , Unnikrishnan Reshmi 
Published: December 2022

AbstractUndifferentiated embryonal sarcoma (UES) is a highly malignant hepatic neoplasm, which occurs mostly in pediatric population. There is a link between embryonal sarcoma and mesenchymal hamartoma as evidenced by clinicopathological overlap and similar genetic abnormality. Here, we report a case of UES in a young female in a background of mesenchymal hamartoma of liver.
Power of Heuristics to Improve Health Information Technology System Design
Authors: Roosan Don , Clutter Justin , Kendall Brian , Weir Charlene 
Published: December 2022

Abstract
Background Clinical decision-making can be prone to error if health system design does not match expert clinicians' higher cognitive skills. There is a gap in understanding the need for the importance of heuristics in clinical decision-making. The heuristic approach can provide cognitive support in designing intuitive health information systems for complex cases.
Objective We explored complex decision-making by infectious diseases (ID) clinicians focusing on fast and frugal heuristics. We hypothesized that ID clinicians use simple heuristics to understand complex cases using their experience.
Methods The study utilized cognitive task analysis and heuristics-based decision modeling. We conducted cognitive interviews and provided clinicians with a fast-and-frugal tree algorithm to convert complex information into simple decision algorithms. We conducted a critical decision method–based analysis to generate if–then logic sentences from the transcript. We conducted a thematic analysis of heuristics and calculated the average time to complete and the number of crucial information in the decision nodes.
Results A total of 27 if–then logic heuristics sentences were generated from analyzing the data. The average time to construct the fast-and-frugal trees was 1.65 ± 0.37 minutes, and the average number of crucial pieces of information clinicians focused on was 5.4 ± 3.1.
Conclusion Clinicians use shortcut mental models to reduce complex cases into simple mental model algorithms. The innovative use of artificial intelligence could allow clinical decision support systems to focus on creative and intuitive interface design matching the higher cognitive skills of expert clinicians.
FAIR Aspects of a Health Information Protection and Management System
Authors: Delgado Jaime , Llorente Silvia 
Published: December 2022

Abstract
Background Privacy management is a key issue when dealing with storage and distribution of health information. However, FAIR (Findability, Accessibility, Interoperability, and Reusability) principles when sharing information are in increasing demand in several organizations, especially for information generated in public-funded research projects.
Objectives The two main objectives of the presented work are the definition of a secure and interoperable modular architecture to manage different kinds of medical content (xIPAMS [x, for Any kind of content, Information Protection And Management System] and HIPAMS [Health Information Protection And Management System]), and the application of FAIR principles to that architecture in such a way that privacy and security are compatible with FAIR.
Methods We propose the concept of xIPAMS as a modular architecture, following standards for interoperability, which defines mechanisms for privacy, protection, storage, search, and access to health-related information.
Results xIPAMS provides FAIR principles and preserves patient's privacy. For each module, we identify how FAIR principles apply.
Conclusions We have analyzed how xIPAMS, and in particular HIPAMS (Health content), support the FAIR principles focusing on security and privacy. We have identified the FAIR principles supported by the different xIPAMS modules, concluding that the four principles are supported. Our analysis has also considered a possible implementation based on the concept of DACS (Document Access and Communication System), a system storing medical documents in a private and secure way. In addition, we have analyzed security aspects of the FAIRification process and how they are provided by xIPAMS modules.
Anastomotic Considerations in Crohn's Disease
Authors: Kann Brian R. 
Published: December 2022

AbstractA number of factors should be considered when performing an intestinal anastomosis in the setting of surgery for Crohn's disease. Preoperative risk factors, such as malnutrition, abdominal sepsis, and immunosuppressive medications, may increase the risk of postoperative anastomotic complications and alter surgical decision-making. The anatomical configuration and technique of constructing the anastomosis may have an impact on postoperative function and risk of recurrence, particularly in the setting of ileocolic resection, where the Kono-S anastomosis has gained popularity in recent years. There may be circumstances in which it may be more appropriate to perform an ostomy either without an anastomosis or to temporarily divert an anastomosis when the risk of anastomotic complications is felt to be high. In the setting of total abdominal colectomy or proctocolectomy for Crohn's colitis, restorative procedures may appropriate in lieu of a permanent stoma in certain scenarios.
Modelling and predicting enterprise-level cyber risks in the context of sparse data availability
Authors: Zängerle Daniel , Schiereck Dirk 
Published: December 2022

AbstractDespite growing attention to cyber risks in research and practice, quantitative cyber risk assessments remain limited, mainly due to a lack of reliable data. This analysis leverages sparse historical data to quantify the financial impact of cyber incidents at the enterprise level. For this purpose, an operational risk database—which has not been previously used in cyber research—was examined to model and predict the likelihood, severity and time dependence of a company’s cyber risk exposure. The proposed model can predict a negative time correlation, indicating that individual cyber exposure is increasing if no cyber loss has been reported in previous years, and vice versa. The results suggest that the probability of a cyber incident correlates with the subindustry, with the insurance sector being particularly exposed. The predicted financial losses from a cyber incident are less extreme than cited in recent investigations. The study confirms that cyber risks are heavy-tailed, jeopardising business operations and profitability.
Secondary school students’ attitude towards mathematics word problems
Authors: Wakhata Robert , Mutarutinya Védaste , Balimuttajjo Sudi 
Published: December 2022

AbstractStudents’ positive attitude towards mathematics leads to better performance and may influence their overall achievement and application of mathematics in real-life. In this article, we present the findings of an investigation on students’ attitude towards linear programming (LP) mathematics word problems (LPMWPs). An explanatory sequential quasi-experimental design involving a pre-intervention-intervention-post-intervention non-equivalent control group was adopted. A sample of 851 grade 11 Ugandan students (359 male and 492 female) from eight secondary schools (public and private) participated. Cluster random sampling was applied to select respondents from eight schools; four from central Uganda and four from eastern Uganda. The attitude towards mathematics inventory-short form (ATMI-SF) was adapted (with α = 0.75) as a multidimensional measurement tool for measuring students’ attitude towards LPMWPs. The results revealed that students’ attitude towards LPMWPs was generally negative. Enjoyment, motivation, and confidence were weekly negatively correlated while usefulness was positively correlated. Additionally, the results found no significant statistical relationship between students’ attitudes towards LPMWPs and their age, gender, school location, school status, and school ownership. The discrepancy is perhaps explained by both theoretical and/or psychometric limitations, and related factors, for instance, students’ academic background, school characteristics, and transitional beliefs from primary to secondary education. This study acknowledges the influence of and supplements other empirical findings on students’ attitude towards learning mathematics word problems. The present study provides insight to different educational stakeholders in assessing students’ attitude towards LPMWPs and may provide remediation and interventional strategies aimed at creating students’ conceptual change. The study recommends that teachers should cultivate students’ interests in mathematics as early as possible. Varying classroom instructional practices could be a remedy to enhance students’ understanding, achievement, and, motivation in learning mathematics word problems. The teachers’ continuous professional development courses should be enacted to improve instruction, assessment, and students’ attitude. Overall, the study findings support the theoretical framework for enhancing the learning of mathematics word problems in general and LP in particular.
Designing fair annual bonus formulations for workers: A case study of the state-owned enterprise cement holding in Indonesia
Authors: Subiyanto Effnu , Kurniawan Roy 
Published: December 2022

AbstractA bonus is an additional annual incentive for labour, as part of remuneration package systems, that goes hand-in-hand with a tantième for boards of commissioners and directors. This practical business is common in industrial relations for maintaining a spirit of productivity and loyalty. However, practices to distribute bonuses remain undisclosed and unknown, according to the views of labour. Without an earlier mutual agreement between parties, consisting of labour representatives and management, management unilaterally decides a specific bonus formulation that takes effect immediately. The management ignored suggestions and advice from labour as its partner; worse, there were no discussions between parties in advance. There are no equal labour and management rights to build a better industrial relations climate. We employed mixed methods and conducted multidisciplinary studies to determine cluster and bonus pool allocation with relevant peers to investigate how to build a fair bonus formulation. We adopted a target-based method rather than an outcome-based framework after several exercises. The most important finding is that the bonus formulation, configured from the annual bonus, utilised three underpinning percentiles (P): P-25, P-50, and P-75 implying the lowest, medium, and highest total remuneration for labour, respectively. We determine that success indicators in developing fair bonus formulation stand on how high total remuneration has been achieved by labour towards the median level of peers. The higher the value passed over the median line, the higher the success rate. The present findings contribute to building fair annual bonus formulations in the cement sector; however, other industrial sectors can use them with adequate adjustments.
Realization of homogeneous dielectric barrier discharge in atmospheric pressure argon and the effect of beads on its characteristics
Authors: RAN Junxia , ZHANG Xuexue , ZHANG Yu , WU Kaiyue , ZHAO Na , HE Xingran , DAI Xiuhong , LIANG Qihang , LI Xuechen 
Published: December 2022

Abstract
This paper describes the realization of a homogeneous dielectric barrier discharge (DBD) in argon at atmospheric pressure. The effect of the morphology of the dielectric surface (especially the dielectric surface covered by hollow ceramic beads (99% Al2O3) with different diameters) on discharge is investigated. With different dielectrics, the argon DBD presents two discharge modes: a filamentary mode and a homogeneous mode. Fast photography shows that the filamentary mode operates in a streamer discharge, and the homogeneous mode operates in a Townsend discharge regime. It is found that a homogeneous discharge can be generated within a certain voltage range. The voltage amplitude range decreases, and the breakdown voltage increases with the increase in the mean diameter of the ceramic beads. Waveforms of the total current and optical emission signal present stochastic pulses per half voltage cycle for the filamentary mode, whereas there is one single hump per half voltage cycle for the homogeneous mode. In the homogeneous mode, the intensity of the optical emission decreases with the mean diameter of the ceramic beads. The optical emission spectrum is mainly composed of atomic lines of argon and the second positive system of molecular nitrogen. It reveals that the electron density decreases with the increasing mean diameter of the ceramic beads. The vibrational temperature increases with the increasing mean diameter of the ceramic beads. It is believed that a large number of microdischarges are formed, and smaller ceramic beads have a larger activation surface area and more point discharge. Electrons liberated in the shallow well and electrons generated from microdischarges can increase the secondary electron emission coefficient of the cathode and provide initial electrons for discharge continuously. Therefore, the breakdown electric field is reduced, which contributes to easier generation of homogeneous discharge. This is confirmed by the simulation results.
Symbiotic Fungi Associated With Xyleborine Ambrosia Beetles (Coleoptera: Curculionidae: Scolytinae) and the Imperative of Global Collaboration
Authors: Osborn Rachel K , Castro Jessenia , Duong Tuan A , Hulcr Jiri , Li You , Martínez Malena , Cognato Anthony I 
Published: December 2022

AbstractAmbrosia beetles from the tribe Xyleborini are part of nearly all forest ecosystems. Because of their small size, haplodiploid mating structure, and protected lives inside the sapwood of woody plants, they have a unique ability to expand into new regions via inadvertent human transport. A small number of invasive xyleborines cause significant damage to forests, lumber concerns, and agricultural systems. Most ambrosia pests damage or kill trees by the accumulation of beetle attacks, one is known to cause tree death through the introduction of pathogenic fungus into susceptible Lauraceae trees. The relationships between ambrosia fungi and their beetle vectors range from mutualistic symbiosis to facultative association, but most remain unstudied. Unresolved taxonomies, convergent morphologies, and the difficulty of sampling ambrosia fungi over their entire global ranges make comprehensive surveys of ambrosia fungi difficult to achieve. Ambrosia fungi from Europe and North America are moderately well documented, however, we have yet to sufficiently document those from Africa, Asia, Australia, and South America. Worldwide cooperation to improve and standardize scientific study of the ambrosia symbioses is needed to better understand these impactful organisms.
Smoking-Related Interstitial Fibrosis (SRIF) in Patients Presenting With Diffuse Parenchymal Lung Disease
Authors: Vehar Susan J , Yadav Ruchi , Mukhopadhyay Sanjay , Nathani Avantika , Tolle Leslie B 
Published: December 2022

AbstractObjectivesTo describe the clinical, radiologic, and pathologic findings in cases where smoking-related interstitial fibrosis (SRIF) was diagnosed in surgical lung biopsy specimens from patients with clinical and imaging features of diffuse parenchymal lung disease (DPLD).MethodsCases were included in this study if patients had clinical and imaging evidence of DPLD and surgical lung biopsy specimens revealed SRIF. A dedicated multidisciplinary conference was held to correlate clinical, radiologic, and pathologic findings.ResultsSix cases met inclusion criteria; all six (five women/one man, aged 42-57 years, mean age 47 years) were either current smokers (five of six) or ex-smokers (one of six) and were evaluated for respiratory symptoms and abnormal pulmonary function tests, most commonly reduced forced vital capacity (n = 3) and diffusing capacity for carbon monoxide (n = 6). The most common imaging abnormalities were bilateral ground-glass opacities, which correlated with histopathologic SRIF. Follow-up of up to 10 years showed stable or improved clinical symptoms, pulmonary function tests, and radiologic findings with smoking cessation (three patients) or a decrease in smoking (three patients). No specific treatments were given, and those treated with empiric corticosteroid tapers did not show discernible responses.ConclusionsSRIF can present as clinically meaningful diffuse parenchymal lung disease in relatively young heavy smokers, characterized by bilateral ground-glass opacities and a stable clinical course.
Hyaline Protoplasmic Astrocytopathy in the Setting of Epilepsy
Authors: Alzoubi Hiba , Nobile Giulia , d’Amati Antonio , Nobili Lino , Giacomini Thea , Tortora Domenico , Gaggero Gabriele , Gianno Francesca , Giangaspero Felice , Antonelli Manila , Consales Alessandro 
Published: December 2022

AbstractObjectivesCerebral hyaline protoplasmic astrocytopathy (HPA) is a clinicopathologic entity characterized by eosinophilic cytoplasmic inclusions within astrocytes. It has been observed in a subset of patients with early-onset epilepsy, brain malformations, and developmental delay. The exact association of this entity with epilepsy is still unknown. This report, with its review of the literature, aims to summarize HPA features to raise awareness regarding this entity.MethodsWe report on 2 HPA cases and critically review the literature.ResultsApproximately 42 cases of HPA have been reported, including the 2 cases presented here, consisting of 23 female and 19 male patients. Patient age ranged from 3 to 39 years. All patients had early-onset seizures (3-20 months of age), ranging from partial to generalized, that were refractory despite treatment with antiepileptic drugs. Postoperative follow-up intervals ranged from 2 to 93 months, and the clinical outcome was graded according to the Engel classification, showing variable results.ConclusionsClinicians should consider HPA in differential diagnosis in patients with intractable seizures, especially when they are associated with developmental delay and brain malformations. Increasing awareness of this entity among pathologists may promote better understanding of this condition as well as better diagnosis and treatment for these patients.
Computer-Based Natural Language Search Applied to the Electronic Medical Record for Tonsil Triage
Authors: Pacheco M Cristina , Hiraiwa Paul , Finn Laura S , Kapur Raj 
Published: December 2022

AbstractObjectivesTo determine significant histologic findings in tonsils and categorize clinical settings in which they occur to identify cases benefiting from histopathologic examination using a computer-based natural language search (NLS) applied to the electronic medical record.MethodsThe pathology database was queried for tonsillectomy cases accessioned between 2002 and 2018. Tonsils with microscopic examination were reviewed, and indication for examination and diagnoses were tallied. Clinical risk of malignancy was correlated with findings. A NLS was used to interrogate preoperative clinical records of the same group of patients. The search identified cases at risk of significant histologic findings and was implemented as part of standard practice.ResultsOf the 18,733 bilateral tonsillectomies identified in the pathology database, 494 were palatine tonsils that underwent microscopic examination, 134 had indications concerning for malignancy, and 14 had significant findings on histologic examination. When the NLS was applied to the medical record of the same group, 223 cases were identified as having risk of malignancy, including all flagged by surgeons and pathologists and 89 additional cases. Clinical implementation resulted in identification of all cases benefiting from examination.ConclusionsA NLS applied to the electronic medical record to select tonsils for examination was superior to relying on surgeons and pathologists.
Destabilizing Racial Discourses in Casual Talk-in-interaction
Authors: Blain Hayden , Diskin-Holdaway Chloé 
Published: December 2022

Abstract
Racialized descriptions are a constant practice in our societies and a fundamental aspect of racial discourses. This paper uses conversation analytic tools within a Foucauldian perspective on discourse to investigate how discourses of race are (re)produced, and consequently navigated, in talk-in-interaction among speakers of Chinese. Four instances of racialized person description, taken from a larger corpus of 16 hours of casual conversation among Chinese migrants in Melbourne and their acquaintances, are explored in detail. The analysis identifies two interactional sequences, joking and accounting sequences, which allow participants to resist racialized descriptions while still orienting to the interactional preference for sociality in casual conversation. The paper argues that casual and friendly interaction may provide empirical evidence for how discourses of race are destabilized at the level of talk-in-interaction.