bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facile synthesis of hierarchically structured MIL-53(Al) with superior properties using an environmentally-friendly ultrasonic method for separating lead ions from aqueous solutions
Authors: Ahadi Niusha , Askari Sima , Fouladitajar Amir , Akbari Iman 
Published: February 2022

AbstractThe present study aims at investigating sonochemically synthesized MIL-53(Al) and its applications in adsorption lead ions from aqueous solution. XRD, FESEM, BET, and FTIR analyses were employed to identify and characterize MIL-53(Al). The ultrasonic-assisted synthesis procedure results in reducing the synthesis time to 24 h; however, the conventional synthesis of MIL-53(Al) takes 3 days. Applying ultrasonic waves also leads to increase of the specific surface area up to 50% more than that of synthesized by the conventional method, as well as creating the hierarchical MIL-53(Al) structure which reduces the mass transfer limitation of ions into internal micropores. The optimum conditions for removing lead ions are pH of 6, Pb+2 ion concentration of 20 mg/L, contact time of 60 min, adsorbent dose of 0.04 g, and temperature of 318 K with the removal efficiency of 97.63%. The experimental adsorption equilibrium and kinetic data fit the Langmuir isotherm and pseudo-second-order kinetic models, respectively. Moreover, the usage of sonochemically synthesized MIL-53(Al), for the first time as an adsorbent in heavy metal removal points to the great potential of this new environmentally-friendly adsorbent in removing lead ions from aqueous solutions
Prediction of serine phosphorylation sites mapping on Schizosaccharomyces Pombe by fusing three encoding schemes with the random forest classifier
Authors: Tasmia Samme Amena , Kibria Md. Kaderi , Tuly Khanis Farhana , Islam Md. Ariful , Khatun Mst Shamima , Hasan Md. Mehedi , Mollah Md. Nurul Haque 
Published: February 2022

AbstractSerine phosphorylation is one type of protein post-translational modifications (PTMs), which plays an essential role in various cellular processes and disease pathogenesis. Numerous methods are used for the prediction of phosphorylation sites. However, the traditional wet-lab based experimental approaches are time-consuming, laborious, and expensive. In this work, a computational predictor was proposed to predict serine phosphorylation sites mapping onSchizosaccharomyces pombe(SP) by the fusion of three encoding schemes namely k-spaced amino acid pair composition (CKSAAP), binary and amino acid composition (AAC) with the random forest (RF) classifier. So far, the proposed method is firstly developed to predict serine phosphorylation sites forSP. Both the training and independent test performance scores were used to investigate the success of the proposed RF based fusion prediction model compared to others. We also investigated their performances by 5-fold cross-validation (CV). In all cases, it was observed that the recommended predictor achieves the largest scores of true positive rate (TPR), true negative rate (TNR), accuracy (ACC), Mathew coefficient of correlation (MCC), Area under the ROC curve (AUC) and pAUC (partial AUC) at false positive rate (FPR) = 0.20. Thus, the prediction performance as discussed in this paper indicates that the proposed approach may be a beneficial and motivating computational resource for predicting serine phosphorylation sites in the case of Fungi. The online interface of the software for the proposed prediction model is publicly available athttp://mollah-bioinformaticslab-stat.ru.ac.bd/PredSPS/.
Enhanced antibacterial effect of a novel Friunavirus phage vWU2001 in combination with colistin against carbapenem-resistant Acinetobacter baumannii
Authors: Wintachai Phitchayapak , Phaonakrop Narumon , Roytrakul Sittiruk , Naknaen Ampapan , Pomwised Rattanaruji , Voravuthikunchai Supayang Piyawan , Surachat Komwit , Smith Duncan R. 
Published: February 2022

AbstractThe emergence of carbapenem-resistant Acinetobacter baumannii (CRAB) has been increasingly reported, leading to greater challenges in treating infections. With the development of phage therapy and phage-antibiotic combinations, it is promising to improve the treatment of bacterial infections. In the present study, a novel vB_AbaP_WU2001 (vWU2001) phage-specific CRAB with a genome of 40,792 bp was isolated. Genomic analysis disclosed that it belongs to the Autographiviridae family of the order Caudovirales. Phage vWU2001 had a broad host range with a high adsorption rate, short latent period, large burst size and good stability. The phage could reduce preformed biofilms and inhibit biofilm formation. The combination of phage vWU2001 and colistin had significantly higher bacterial growth inhibition activity than that of phage, or colistin alone. The efficacy of the combined treatment was also evaluated in Galleria mellonella. Evaluation of its therapeutic potential showed that the combination of phage and colistin resulted in a significantly greater increase in G. mellonella survival and in bacterial clearance, as compared with that of phage or colistin alone, indicating that the combination was synergistic against CRAB. The results demonstrated that phage vWU2001 has the potential to be developed as an antibacterial agent.
Mechanical strength variability of deformed reinforcing steel bars for concrete structures in Ethiopia
Authors: Achamyeleh Tariku , Çamur Hüseyin , Savaş Mahmut A. , Evcil Ali 
Published: February 2022

AbstractThe paper presents statistical analysis of mechanical strength and linear density properties of deformed reinforcing Grade 60 steel bars. Two different lots of samples are identified based on test years for the years 2015–2017 as Lot 1 and 2018–2020 as Lot 2. Yield strength (YS), tensile strength (TS), elongation, mass per length and characteristic ratio of TS and YS are analyzed for rebar diameters of 8, 10, 12 and 16 mm considering both lots. Mechanical and linear density properties are compared statistically using range, mean, standard deviation, coefficient of variance, skewness and kurtosis of the recorded sets of values. Moreover, the results of YS, TS and elongation are analyzed separately by one-way analysis of variance for both lots. The result shows that the aggregate mean values of YS, TS and elongation for Lot 1 and Lot 2 are 593.1 MPa, 701.1 MPa, 14.78%; and 572.5 MPa, 673.8 MPa, 15.47%, respectively. Even though there is a slight decrement in values of YS and TS and increment in elongation from Lot 1 to Lot 2, both lots exceeded values recommended by ASTM A615 standard. Furthermore, with 95% confidence interval, one-way analysis of variance showed that the aggregate data of rebars are dissimilar in terms of YS, TS and percentage elongation with figures showing decrement from Lot 1 to Lot 2.
Citral mitigates inflammation of Caco-2 cells induced by Cronobacter sakazakii
Authors: Guo Du , Bai Fangting , Zhan Xiangjun , Zhang Wenting , Jin Tong , Wang Yutang , Xia Xiaodong , Shi Chao 
Published: February 2022

The anti-inflammatory effect and mechanism of citral in Cronobacter sakazakii-stimulated Caco-2 cells.
A Cross-Linguistic Validation of the Test for Rating Emotions in Speech: Acoustic Analyses of Emotional Sentences in English, German, and Hebrew
Authors: Carl Micalle , Icht Michal , Ben-David Boaz M. 
Published: February 2022

Purpose:
The Test for Rating Emotions in Speech (T-RES) has been developed in order to assess the processing of emotions in spoken language. In this tool, spoken sentences, which are composed of emotional content (anger, happiness, sadness, and neutral) in both semantics and prosody in different combinations, are rated by listeners. To date, English, German, and Hebrew versions have been developed, as well as online versions, iT-RES, to adapt to COVID-19 social restrictions. Since the perception of spoken emotions may be affected by linguistic (and cultural) variables, it is important to compare the acoustic characteristics of the stimuli within and between languages. The goal of the current report was to provide cross-linguistic acoustic validation of the T-RES.

Method:
T-RES sentences in the aforementioned languages were acoustically analyzed in terms of mean F0, F0 range, and speech rate to obtain profiles of acoustic parameters for different emotions.

Results:
Significant within-language discriminability of prosodic emotions was found, for both mean F0 and speech rate. Similarly, these measures were associated with comparable patterns of prosodic emotions for each of the tested languages and emotional ratings.

Conclusions:
The results demonstrate the lack of dependence of prosody and semantics within the T-RES stimuli. These findings illustrate the listeners' ability to clearly distinguish between the different prosodic emotions in each language, providing a cross-linguistic validation of the T-RES and iT-RES.
Feasibility of Assessing Expressive and Receptive Vocabulary via Telepractice for Early Elementary-Age Children With Language Impairment
Authors: Schmitt Mary Beth , Tambyraja Sherine , Thibodeaux Megan , Filipkowski Jen 
Published: February 2022

Purpose:
Due to the COVID-19 pandemic, millions of school-age children with language impairment (LI) and their speech-language pathologists (SLPs) relied on telepractice service delivery models. Unfortunately, the dearth of evidence and procedural guidance available to SLPs has made this transition challenging at best.

Method:
The current study utilized a sample of 20 young children with LI to determine the feasibility of procedures necessary for conducting vocabulary assessments via telepractice platforms and the reliability of scoring participant responses using standardized assessments.

Results:
Study findings resulted in numerous practical suggestions for SLPs working with young children with LI via telepractice. Results suggest that these adaptations result in strong interrater reliability for scoring participant responses in an online format.

Conclusion:
Study findings suggest that conducting telepractice assessments can be a useful and reliable tool for school-based SLPs, with implications reaching beyond the pandemic era.
Shaped beam synthesis via semidefinite relaxation (SDR) based on magnitude least squares (MLS)
Authors: Hu Mengkai , Dou Xiuquan , Liu Qifan , Zhu Xingsheng 
Published: February 2022

AbstractShaped beam synthesis of array antennas has attracted the attention of many researchers in recent years and has been widely used in many scenarios. In the previous methods, finding the feasible solution with beam pattern mask constraints has been applied widely, but the solution may not exist with an improper mask. Besides, if the array size is large, the dimension of solution is high, which causes the solution procedure slow. In this study, from the perspective of the magnitude least squares (MLS) model, combined with the semidefinite relaxation (SDR) technique, a new beam pattern synthesis algorithm is derived. The MLS model can guarantee that the solution always exists and can reduce the dimension of solution via introducing auxiliary variable and non‐uniform angular sampling. Simulation results show that this algorithm is effective, can approximate the main lobe well and obtain lower side lobes in contrast to the reference method.
Impact of non-thermal particles on the spectral and structural properties of M87
Authors: Fromm Christian M. , Cruz-Osorio Alejandro , Mizuno Yosuke , Nathanail Antonios , Younsi Ziri , Porth Oliver , Olivares Hector , Davelaar Jordy , Falcke Heino , Kramer Michael , Rezzolla Luciano 
Published: February 2022

Context. The recent 230 GHz observations of the Event Horizon Telescope are able to image the innermost structure of M 87 and show a ring-like structure that agrees with thermal synchrotron emission generated in a torus surrounding a supermassive black hole. However, at lower frequencies, M 87 is characterised by a large-scale and edge-brightened jet with clear signatures of non-thermal emission. In order to bridge the gap between these scales and to provide a theoretical interpretation of these observations, we perform general relativistic magnetohydrodynamic simulations of accretion onto black holes and jet launching.
Aims. M 87 has been the target for multiple observations across the entire electromagnetic spectrum. Among these, very large baseline interferometry (VLBI) observations provide unique details of the collimation profile of the jet down to several gravitational radii. We aim to model the observed broad-band spectrum of M 87 from the radio to the near-IR regime and at the same time, fit the jet structure as observed with global millimeter-VLBI at 86 GHz.
Methods. We used general relativistic magnetohydrodynamics and simulated the accretion of the magnetised plasma onto Kerr black holes in 3D. The radiative signatures of these simulations were computed taking different electron distribution functions into account, and a detailed parameter survey was performed in order to match the observations.
Results. The results of our simulations show that magnetically arrested disks around fast-spinning black holes (a⋆ ≥ 0.5) together with a mixture of thermal and non-thermal particle distributions are able to simultaneously model the broad-band spectrum and the innermost jet structure of M 87.
Outcome-relevante Anästhesiologie: präoperative Vorbereitung und Optimierung
Authors: Neef Vanessa , Zacharowski Kai , Piekarski Florian 
Published: February 2022

ZusammenfassungDie präoperative Vorbereitung und Optimierung ist zentraler Bestandteil der anästhesiologischen Prämedikationsvisite. Ziel ist es, postoperative Komplikationen zu vermeiden und die
Patientensicherheit zu erhöhen. In diesem Artikel werden kardiale, respiratorische und metabolische Risikofaktoren von Patienten vor elektiven nicht herz-thoraxchirurgischen Eingriffen
behandelt und deren Diagnostik- und Optimierungsmöglichkeiten dargestellt.
Outcome-relevante Anästhesiologie: peri- und postoperative Anämiebehandlung
Authors: Helmer Philipp , Kranke Peter , Schlesinger Tobias , Hottenrott Sebastian , Zacharowski Kai , Choorapoikayil Suma , Meybohm Patrick 
Published: February 2022

ZusammenfassungPatient Blood Management (PBM) hat sich zum Ziel gesetzt, das Ausmaß einer präoperativen Anämie zu reduzieren, unnötige Blutverluste zu vermeiden und einen rationalen Umgang mit
Blutprodukten zu ermöglichen. Aufgrund verschiedenster Limitationen gelingt bislang nur in wenigen deutschen Krankenhäusern eine frühzeitige Behandlung einer präoperativen Anämie. Vor diesem
Hintergrund rückt die peri- und postoperative Phase zunehmend in den Fokus, um verschiedene präventive und therapeutische Maßnahmen zur Behandlung einer (postoperativen) Anämie umzusetzen.
Diese werden in diesem Beitrag umfassend vorgestellt.
Extrakorporale Behandlungsstrategien der Sepsis
Authors: Stahl Klaus , Bode Christian , David Sascha 
Published: February 2022

Zusammenfassung
Hintergrund Die Mortalität der Sepsis bleibt auch im 21. Jahrhundert sehr hoch. Verschiedene adjuvante Strategien zur extrakorporalen Zytokinelimination wurden als zusätzliche
therapeutische Maßnahmen bei Sepsis und septischem Schock untersucht.
Ziele Zusammenfassung einer Auswahl extrakorporaler Blutreinigungstechniken und der aktuellen Erkenntnisse in der klinischen Anwendung mit besonderem Schwerpunkt auf dem
therapeutischen Plasmaaustausch.
Methoden Nicht systematische Literaturrecherche.
Ergebnisse Verschiedene extrakorporale Blutreinigungstechniken mit unterschiedlichen Evidenzniveaus hinsichtlich Zytokinelimination, Verbesserung der Hämodynamik und Verringerung der
Mortalität werden derzeit klinisch eingesetzt. Die am ausführlichsten untersuchten Modalitäten umfassen die hochvolumige Hämofiltration/Dialyse mit und ohne High-Cut-off-Filter sowie
Hämoadsorptionstechniken (einschließlich CytoSorb- und Polymyxin-B-Filter). Trotz teilweise ermutigender Beobachtungen bezüglich der Entfernung proinflammatorischer Zytokine und verbesserten
Hämodynamik zeigten randomisierte Outcome-Studien bislang keinen positiven Einfluss auf das Überleben. Aufgrund der Verwendung von Spenderplasma als Substitutionsflüssigkeit stellt der
therapeutische Plasmaaustausch das einzige Verfahren dar, das neben einer reinen Elimination zusätzlich verbrauchte protektive Faktoren ersetzen kann.
Schlussfolgerungen Die Anwendung extrakorporaler Blutreinigungsmethoden kann für Sepsispatienten außerhalb klinischer Studien bisher nicht empfohlen werden, da derzeit keine Beweise
für ihre Wirksamkeit vorliegen. Zukünftige Untersuchungen sollten darauf abzielen, das Patientenkollektiv hinsichtlich des klinischen Schweregrads, des Zeitpunkts der Intervention und
verschiedener inflammatorischer (Sub-)Phänotypen zu homogenisieren.
Anästhesie und perioperatives Management der Karotis-Endarteriektomie (CEA)
Authors: Gaik Christine , Wiesmann Thomas 
Published: February 2022

ZusammenfassungNachdem in Teil 1 des Beitrags die Anästhesieverfahren vorgestellt wurden 1, befasst sich der 2. Teil mit dem apparativen und nicht-apparativen
intraoperativen Neuromonitoring sowie den perioperativen Komplikationen und vermittelt relevante Aspekte des Neuromonitorings im Rahmen der CEA. Die perioperativen Komplikationen werden
insbesondere für die frühe postoperative Phase im Aufwachraum und auf der Station erläutert und Lösungsstrategien dargestellt.
Vorausschauende Entlassungskriterien nach Lu-177-PSMA-Therapie – Diskussion unterschiedlicher Szenarien
Authors: Kranert Wolfgang Tilman , Bockisch Benjamin , Wichert Jennifer , Gröner Daniel , Sabet Amir , Baumgarten Justus , Nguyen Ngoc Linh Quyen Christina , Grünwald Frank , Happel Christian 
Published: February 2022

Zusammenfassung
Ziel Ziel ist es, einen praxisorientierten Beitrag zur Diskussion eines Algorithmus zur Entlassung unter Strahlenschutzgesichtspunkten von Patienten nach Therapien mit Lu-177 markiertem PSMA zu leisten. Dieser kann als Basis zur Weiterentwicklung von Vorgaben für die Entlassungspraxis für andere zukünftige Therapien mit offenen radioaktiven Stoffen dienen.
Material und Methoden Anhand der Analyse der Behandlungsdaten von 478 Zyklen Lu-177-PSMA-617 (140 Patienten) wurde der Zusammenhang zwischen Restaktivität im Patienten und der damit verbundenen Dosisleistung erstellt. Aus den kinetischen Daten regelmäßiger intratherapeutischer Ganzkörpermessungen mit einer Sonde (biexponentieller Fit) wurden daraus Szenarien für die Entlassung entwickelt.
Ergebnis 34 % der Patienten wurden 3- bis 5-mal in einem Kalenderjahr behandelt. 1 mSv pro Kalenderjahr in 2 m Entfernung kann bei der prospektiven Entlassung von 3 bzw. 4 Therapiezyklen pro Jahr nach 72 Stunden stationärem Aufenthalt in 10 % bzw. 15 % der Fälle nicht eingehalten werden. Die mittlere spezifische Dosisleistung im Patienten betrug 0,00462µSv/(h MBq) in 1 m Entfernung. Ein allgemeingültiger quantitativer Zusammenhang der Dosisleistung mit der Restaktivität im Patienten konnte nicht gefunden werden.
Schlussfolgerung Wegen des Ansatzes einer Mehrfachbehandlung der mit Lu-177-PSMA therapierten Patienten müssen die Entlassungsbedingungen prospektiv angepasst werden. Die Zugrundelegung der physikalischen Halbwertszeit von Lu-177 und von 4 Behandlungen im Kalenderjahr führt zu einer konservativen, übersichtlichen Regelung.
Visualized Urethral Mobility Profile During Urine Leakage in Supine and Standing Positions
Authors: Zhao Baihua , Wen Lieming , Liu Dan , Huang Shanya 
Published: February 2022

Abstract
Objectives To describe the urethral course and position during urine leakage based on the visualized urethral mobility profile (UMP) and to explore the differences between supine and standing positions.
Method This was a prospective study of 100 women with SUI and 100 control women who underwent a cough stress test (CST) with transperineal ultrasound (TPUS) in supine and standing positions. In the mid-sagittal plane, the UMP software automatically placed six equidistant points from the bladder neck (point 1) to the external urethral meatus (point 6). It determined the x and y coordinates of the points relative to the symphysis pubis. The distance between the points and symphysis pubis (dist. 1 to 6) was calculated using the formula SQRT (x2 + y2). The visualized UMP was created by reproducing the six points on a bitmap.
Results Valid UMP data of 78 control women and 90 women with SUI were analyzed. In the two positions, distances 1 to 6 were significantly greater in the SUI group than the continent group (all p < 0.05). During Valsalva, the distance between the mid-urethra (dist. 3 and 4) and the symphysis was significantly increased (all p < 0.001) in the SUI group. The visualized UMP showed a similar upper-urethral course in the two groups. The gap between the mid-urethra (points 3 and 4) and symphysis was wider in the SUI group.
Conclusion The visualized UMP in supine and standing positions showed no difference in the bladder neck and upper urethral stability between incontinent and continent women, but mid-urethral stability was weaker in SUI.
Step-By-Step Segmental Analysis of the Fetal Heart with an Uncommon
Situs Anomaly
Authors: Ergani Seval Yilmaz , Yılmaz Osman 
Published: February 2022

AbstractCongenital heart diseases are the most common congenital anomalies during the
fetal period. The diagnosis of complex congenital heart diseases in the fetal
period is not always easy. While evaluating cardiac abnormalities, performing
segmental analysis and step-by-step evaluation will facilitate the diagnosis of
prenatal cardiac diseases. Here, we report a rare variant AV (atrioventricular)
and VA (ventriculoarterial) discordance pattern detected in utero and identified
based on step-by-step segmental analysis.
Convenient Approach to Bicyclic Sultams
Authors: Kostyuk Aleksandr , Filimonchuk Sergiy L. , Nazarenko Kostiantyn , Shvydenko Tetiana , Shvydenko Kostiantyn , Rusanov Eduard B. 
Published: February 2022

AbstractA method for the synthesis of aminomethyl-substituted five-membered sultams has been developed. The aminomethyl sultams were synthesized from the corresponding iodomethyl derivatives by nucleophilic substitution of the iodine atom with sodium azide followed by reduction on Pd/C. This method was further expanded to side-chain-substituted sultams, starting from amino acid esters, to obtain aminomethyl-containing bicycles. The simple practical procedure and available starting amino acid esters, including chiral examples, make various bicyclic sultams readily available.
Nickel-Catalyzed Regioselective Thiolation of Anilides with Thiols
Authors: Kianmehr Ebrahim , Foroumadi Alireza , Doraghi Fatemeh 
Published: February 2022

AbstractAn efficient method for direct thiolation of anilides with thiols using NiCl2·6H2O as the catalyst is developed. Using this method, the desired products were successfully synthesized in moderate to good yields. Initial mechanistic studies suggest that this reaction proceeds through a radical pathway.
Retrograde Percutaneous Intervention of Chronic Total Occlusion Step by Step
Authors: Rao V. Suryaprakasa 
Published: February 2022

AbstractRetrograde approach for chronic total occlusion percutaneous intervention is the ultimate technique for success in cases of high Japan-CTO (JCTO) score, ostial locations, long calcific lesions with calcium, and in retry cases. There are various methods of collateral cross, reverse controlled antegrade and retrograde tracking, and externalization, which are practiced by various experts. Intravascular ultrasound-guided procedures will minimize complications and increase chances of stent optimization for better outcomes.