bluuebunny/crossref_metadata_2025_split huggingface dataset:
Topical natural-origin polynucleotides in radiation-induced skin and mucosal toxicity
Authors: Giudici Stefania , Maggio Francesca , Bertocchi Marco , Lucido Maria Rosaria , Corvò Renzo , Orsatti Marco 
Published: October 2022

Seventy to 90 percent of patients who have received radiation treatment struggle with radiation skin and mucosal toxicity. The inflicted damage to progenitor cells and local microcirculation makes it more likely that wounds, infections, and fibrosis may occur; lesions of variable severity often co-exist. Acute erythema, hyperpigmentation, and mild desquamation usually wane in weeks and require only minor treatment. Conversely, the management of persistent radiation dermatitis and telangiectasia remains unsatisfactory; chronic lesions may progress to tissue atrophy and disfiguring fibrosis.
Protrophic, natural-origin polynucleotides, formulated as Class III medical devices, have long shown to be a reliable topical option to stop the progression of radiation-related lesions. The present review illustrates the rationale of polynucleotides in skin and mucosal radiodermatitis management. It also illustrates the clinical results in a series of exploratory clinical studies carried out with polynucleotide devices over the last decade. The examined studies open the way to the high-level clinical research program, which will develop over the next years.
Gouverner l’adaptation de l’agriculture au changement climatique par projet ?
Authors: Boutroue Bétina , Hrabanski Marie , Diao Camara Astou 
Published: October 2022

L’article nourrit les réflexions du numéro spécial sur la normalisation des études sur le problème climatique et sur les « climatisations » différenciées des politiques publiques en questionnant la dynamique d’intégration des enjeux climatiques dans les politiques agricoles au Sénégal. Ce pays se caractérise par sa forte vulnérabilité aux effets du changement climatique et est marqué par une longue tradition d’extraversion et de dépendance vis-à-vis des bailleurs de l’aide internationale. Nous mobilisons le modèle de Candel et Biesbroek d’analyse processuelle de l’intégration, comprenant quatre variables : policy framing , policy goals , policy subsystem involvement et policy instruments . Nous prenons également appui sur la littérature en socio-anthropologie du développement pour remodeler la variable instrumentale du modèle afin de l’adapter au contexte d’un pays « sous régime d’aide ». Nous montrons ainsi que l’adaptation au changement climatique est un enjeu qui est formellement bien intégré aux politiques agricoles au Sénégal, en raison de la circulation de cette norme de politique publique dans les négociations internationales (variable « policy framing »), de son appropriation à l’échelle de l’État du Sénégal (variable « policy goals ») et de son appropriation par les agences administratives dans le cadre d’une compétition institutionnelle pour les ressources de l’adaptation de l’agriculture (variable « subsystem involvement »). Cette intégration trouve pourtant ses limites dans les difficultés de l’État du Sénégal à financer des instruments propres d’adaptation de l’agriculture au changement climatique et dans l’imposition par les bailleurs du mode de gouvernement de l’adaptation par projet (variable instrumentale adaptée du modèle).
La mise en œuvre locale des instruments comme vecteur de déclimatisation des politiques publiques
Authors: Montouroy Yves , Biabiany Océane , Massardier Gilles 
Published: October 2022

L’article présenté ici participe des travaux sur les processus de climatisation et de déclimatisation des politiques publiques, notamment dans le secteur agricole européen. Notre étude montre que la mise en œuvre de la politique agricole commune favorise les marges de manœuvre des acteurs sectoriels locaux, ce qui augmente leur autonomie. Dans la filière banane en Guadeloupe, ces marges de manœuvre donnent lieu à une réinterprétation en défaveur de la prise en charge du changement climatique. Quatre variables concourent à ce processus de déclimatisation par le bas : une mise en œuvre multi-niveaux organisant une définition au local du contenu des instruments programmatiques européens ; une gouvernance polycentrique locale catalysée par la filière banane ; un agenda environnemental cadré sur la lutte contre les produits phytopharmaceutiques et enfin des arrangements locaux fabriqués pour soutenir la compétitivité de la filière. L’article contribue au numéro spécial en décryptant ce que la mise en œuvre sur un territoire et par un secteur produit sur une politique européenne climatisée. Il montre ainsi que l’appel à programmer le changement ne suffit pas à le générer mais qu’il favorise la résistance des acteurs et la « lutte » des problèmes et leur hiérarchisation. Enfin, l’article contribue à la normalisation de l’étude de l’objet climat. Fondé sur une méthodologie qualitative et une enquête de terrain conduite en Guadeloupe, l’article met ainsi en lumière une déclimatisation de la politique agricole à travers le cas de la filière banane. Cette déclimatisation est rendue possible, tout d’abord, parce que le cadrage de l’agenda politique local marginalise l’intégration du changement climatique dans la programmation de la politique agricole et ce, au profit d’une labélisation en termes de transition agroécologique compétitive définie depuis la filière. Ensuite, le contenu technique des instruments climatisés reste dépendant des barrières sectorielles, ici relégitimées au prisme des vulnérabilités locales et des pratiques agricoles existantes. En effet, nous montrons que la mise en relation entre l’agenda politique local et la mise en œuvre des instruments programmatiques est dépendante d’une action collective fortement structurée par la filière. L’enjeu est de faire des instruments européens climatisés les leviers de la transition agroécologique de la filière. Enfin, cela a été rendu possible car l’association représentant la filière a pallié auprès de ses membres les dysfonctionnements de l’État territorial, alors contraint de travailler étroitement avec celle-ci. L’analyse conclut sur la mise en évidence d’un processus de capture associant acteurs publics et la filière.
Séparations conjugales et reconfigurations familiales
Authors: Régnier-Loilier Arnaud 
Published: October 2022

Les ruptures d’union, quelle que soit la forme de celles-ci (mariage, pacs, union libre), sont de plus en plus fréquentes et concernent chaque année de nombreux enfants. À la faveur des remises en couple, les configurations familiales dans lesquelles vivent les enfants se sont diversifiées. Centré sur la situation française, ce « point de repère » revient sur l’ampleur des séparations et leur évolution au cours des dernières décennies. En adoptant à la fois le point de vue des familles mais aussi celui des enfants, il présente la morphologie des familles contemporaines, les modalités de résidence des enfants et aborde diverses formes de vulnérabilité qui peuvent accompagner les séparations.
La tentative de médiation familiale préalable obligatoire (TMFPO) : une obligation qui n’arrive pas à ses fins
Authors: Boussard Valérie , Mato Ornela , Kim Jiyoung 
Published: October 2022

Cet article se propose d’analyser les effets de la tentative de médiation familiale préalable obligatoire instaurée par la loi n° 2016-1547 du 18 novembre 2016 de modernisation de la justice du XXI e siècle (J21), sur le traitement des différends pour lesquels les justiciables saisissent le tribunal. À partir des données statistiques d’un tribunal judiciaire, on peut noter que la médiation obligatoire n’aboutit qu’à un tiers de médiation effective, au sens où les ex-conjoints se sont rencontrés au moins une fois. Elle débouche que très peu d’accords (15 %) et encore moins si on ne compte que les accords totaux (10 %). À partir d’une analyse statistique incluant des données sociodémographiques sur les justiciables, des données sur les raisons de la saisine et des entretiens avec des magistrats, médiateurs et justiciables, l’article donne à voir les cas typiques de déroulement de la médiation : succès (accord partiel ou total) et échec (absence du défendeur à l’entretien d’information, absence de séance de médiation, séance(s) de médiation sans accord). Il montre que le déroulement de la médiation dépend, de façon indépendante ou combinée, du genre, de la raison de la demande, du capital économique, du capital culturel, de l’origine nationale et de l’état des relations entre les ex-conjoints. Hormis de rares cas d’accord et de reprise de dialogue, pour la grande majorité des justiciables, l’obligation de médiation semble essentiellement être une perte de temps et d’énergie.
Teneurs en polyphénols, en flavonoïdes et activités anti oxydantes des rhizomes de Zingiber officinale récoltés dans cinq sites de culture du Cameroun
Authors: Fotsing Stela , Ngogang Marie Paule , Bérenger Nganchouko , Simo Louokdom Josué , Ngogang Jeanne 
Published: October 2022

De nombreuses décoctions de la pharmacopée traditionnelle utilisées pour le traitement de la COVID-19 contiennent des rhizomes de Zingiber officinale ( gingembre). L’un des mécanismes d’action de cette épice serait son action anti oxydante dues à la présence des composés phénoliques. Des échantillons de gingembre sont récoltés à Bangangté, Bafang, Kékem, Santchou et Mélong. Les teneurs moyennes en polyphénols (mEgAT/g ES) des extraits aqueux , hydroalcooliques et éthanoliques sont respectivement de 155,91 ±18,22 ; 321,46 ± 71,90 ; 136,44 ± 28,44 . Celles des flavonoïdes exprimés en mEg Quer/ g ES sont respectivement de 45,24± 13,49 ; 125,43±14,88 ; 76,52±10,80. Les activités antioxydantes varient également en fonction du solvant d’extraction. Avec la méthode FRAP elles sont de 1,34±0,42ng/ ml ; 2,08±0,59 ng/ml ; 1,64±0,49. La méthode PAP confirme ces résultats et donne les valeurs de 1,82±0,51 ng/mL ; 2,46±0,52ng/mL ; 2,06±0,50ng/mL respectivement . Dans tous les cas les rhizomes de Mélong sont plus riches en ces molécules et présentent les meilleures activités antioxydantes /antiradicalaires.

Many decoctions from traditional pharmacopoeia are used to treat Covid-19 contain zingiber officinale rhizomes (gingembre). One of its mechanism of action would come from its antioxidant proprerty due to the presence of phenolic compounds .We therefore determined the contents of polyphenols, flavonoids and antioxidant activities on water, alcoholic and hydroalcoholic extracts of gingembre harvested from Bangangté, Bafang, Kekem, Santchou and Melong. The mean contents of polyphenols expressed in mEgAT/g ES were 155,91 ±18,22; 321,46 ± 71,90 ; 136,44 ± 28,44 in aqueous, , hydro alcoholic and alcoholic extracts respectively. Those of flavonoids expressed in mEg Quer/g ES were 45,24± 13,49 ; 125,43±14,88 ; 76,52±10,80. Antioxidant activities measured according FRAB (1,34±0,42ng/ ml ; 2,08±0,59 ng/ml ; 1,64±0,49.) and PAP (1,82±0,51 ng/mL ; 2,46±0,52ng/mL ; 2,06±0,50ng/ mL ) methods vary according to the type of extract . Polyphenol, flavonoids contents and antioxidant activities from Melong were higher than those of the other sites .
Cerebrovascular modelling for the management of aneurysm embolization using an intrasaccular flow diverter made by 3D printing
Authors: Algin Oktay , Keles Ayse , Oto Cagdas 
Published: October 2022

IntroductionUsing 3-dimensional (3D) printers, the creation of patient-specific models is possible before and after a therapeutic intervention. There are many articles about replicas for training and simulation of aneurysm clipping. However, no paper has focused on 3D replicas obtained from 3-tesla 3D time of flight (3D-TOF) MR angiography for intrasaccular flow diverter (WEB device) embolization of the cerebral aneurysms. In this paper, we aimed to investigate the feasibility of 3D printing models obtained from 3-tesla 3D-TOF data in the management and training of WEB-assisted embolization procedures.Case presentationWe presented a longitudinal case report with several 3D-TOF MRA prints over time. Three-tesla 3D-TOF data were converted into STL and G-code files using an open-source (3D-Slicer) program. We built patient-specific realistic 3D models of a patient with a middle cerebral artery trifurcation aneurysm, which were able to demonstrate the entire WEB device treatment procedure in the pre-intervention and post-intervention periods. The aneurysmatic segment was well displayed on the STL files and the 3D replicas. They allowed visualization of the aneurysmatic segment and changes within a 6-year follow-up period. We successfully showed the possibility of fast, cheap, and easy production of replicas for demonstration of the aneurysm, the parent vessels, and post-intervention changes in a simple way using an affordable 3D printer.Conclusions3D printing is useful for training the endovascular team and the patients, understanding the aneurysm/parent vessels, and choosing the optimal embolization technique/device. 3D printing will potentially lead to greater interventionalist confidence, decreased radiation dose, and improvements in patient safety.
1831 Tarihli Nüfus Sayımı Verileri Üzerinden Samakov Kazasının Demografik ve İktisadî Yapısının İncelenmesi
Authors: DOĞANAY Pınar 
Published: October 2022

Toplumların sosyal ve ekonomik yapısı başta olmak üzere idarî, askerî, dinî ve kültürel alanında bilgi edinilmesine olanak sağlayan nüfus sayımlarının, Osmanlı Devleti’nde tam olarak hangi tarihte yapılmaya başlandığı bilinmemektedir. Günümüze ulaşan en erken kayıtları H.835/M.1431 yılına ait olan bu sayımların amacı, vergi mükellefi olan kimseleri tespit etmektedir. XIX. yüzyıla kadar benzer sebeplerle birkaç farklı sayım sisteminin denendiği Osmanlı Devleti’nde, modern anlamda ilk nüfus sayımı, 1831 yılında yapılmıştır. Asâkir-i Mansûre-i Muhammediyye Ordusu’nun gereksinimi olan erkek nüfus sayısını tespit etmek amacıyla yapılan bu sayımın bir diğer amacı ise halktan alınacak vergileri hesaplamaktır.
Bulgaristan sınırları içerisinde yer alan Samakov Kazasının H.1246/M.1831 tarihli nüfus defterlerinin temel kaynak olarak kullanıldığı bu çalışmada, Samakov Kazasının demografik ve iktisadî yapısı üzerine bir çıkarım oluşturulmaya çalışılmıştır.
XVI. Yüzyıl Osmanlı-Avusturya İlişkileri Tarihine Katkı: 1574 Tarihli Avusturya Ahidnamesi
Authors: AKTAŞ KÜTÜKÇÜ Büşra 
Published: October 2022

Uluslararası hukukun en önemli belgeleri olan Osmanlı ahidnamelerinden günümüze orijinal olarak az sayıda belge ulaşmıştır. Bu belgelerin birçoğu ilgili devletlerin arşivlerinde muhafaza edilmekte olup kimileri bilinmeyen yollarla bu arşivlerden çıkarılmıştır. XVI. yüzyılın birbirine oldukça benzeyen çok uluslu iki güçlü devleti olan Osmanlı ve Avusturya arasındaki doğrudan diplomatik temaslar sonucunda üretilen ahidnamelerden günümüze yalnızca 1562 ve 1565 tarihli iki tanesinin ulaştığı bilinmekte idi. Yakın zamanda Sultan II. Selim’e ait 1574 tarihli ahidnamenin orijinali tarafımızca British Library’de tespit edilmiştir.
Bu makalede öncelikle Sultan II. Selim döneminin sonuna kadar Osmanlı-Avusturya ilişkileri ahidnameler bağlamında incelenmiştir. Daha sonra bu dönem sonuna kadar verilmiş ahidnamelerin neşirleri hakkındaki bilgiler derlenmiştir. Son olarak 1574 tarihli ahidname diplomatik hususiyetleri açısından tahlil edilmiştir. Bu ahidnamenin metni ve dijital nüshası ilk defa bu makale ile neşredilmiş ve diplomatik bilimi açısından XVI. yüzyıl Osmanlı ahidnameleri arasındaki konumu belirlenmeye çalışılmıştır.
The current state of search work in the penal system
Authors: Чайковский Алексей Александрович 
Published: October 2022

В статье рассматриваются особенности деятельности розыскных подразделений уголовно-исполнительной системы на современном этапе. Предметом статьи выступили правовые, теоретические и организационные аспекты деятельности розыскных подразделений пенитенциарного ведомства. Цель исследования - охарактеризовать современное состояние розыскной работы в уголовно-исполнительной системе. Методологическую основу исследования составили анализ, синтез, индукция, системно-структурный метод. В результате проведенной работы определены категории лиц, разыскиваемых розыскными подразделениями уголовно-исполнительной системы, обобщены функции розыскных подразделений службы на федеральном и региональном уровнях, рассмотрено их техническое обеспечение. Кроме того, выявлен ряд проблем, имеющихся в деятельности розыскных подразделений УИС, связанных с задержанием лиц, находящихся в розыске; с основаниями применения сотрудниками в ходе розыскных мероприятий физической силы, специальных средств и огнестрельного оружия; с проведением розыскными подразделениями УИС оперативно-розыскных мероприятий, ограничивающих конституционные права человека и гражданина.
In the article the author discusses the features of the activities of the search units of the penitentiary system at the present stage. The subject of the article is the legal, theoretical and organizational aspects of the activities of the search units of the penitentiary department. The purpose of the study is to characterize the current state of investigative work in the penal system. The methodological basis of the study includes analysis, synthesis, induction, system-structural method. As a result of the work carried out, the categories of persons wanted by the search units of the penitentiary system were determined, the functions of the search units of the service at the federal and regional levels have been summarized, and their technical support have been considered. In addition, a number of problems have been identified in the activities of the search units of the penal system related to the detention of wanted persons; with the grounds for the use by employees in the course of search activities of physical force, special means and firearms; with the conduct of search units of the penitentiary system of operational-search measures that limit the constitutional rights of a person and a citizen.
Effects of temperature and salinity on bubble-bursting aerosol formation simulated with a bubble-generating chamber
Authors: Sofieva Svetlana , Asmi Eija , Atanasova Nina S. , Heikkinen Aino E. , Vidal Emeline , Duplissy Jonathan , Romantschuk Martin , Kouznetsov Rostislav , Kukkonen Jaakko , Bamford Dennis H. , Hyvärinen Antti-Pekka , Sofiev Mikhail 
Published: October 2022

Abstract. A new bubble-generating glass chamber with an extensive set of aerosol production experiments is presented. Compared to the experiments described in the literature since the ground-setting works of Edward C.​​​​​​​ Monahan et al. in 1980s, the current setup is among the medium-sized
installations allowing for accurate control of the air discharge, water
temperature, and salinity. The size and material of the chamber offer a
variety of applications due to its portability, measurement setup
adjustability, and sterilization option. The experiments have been conducted
in a cylindrical bubbling tank of 10 L volume that was filled by
∼ 30 %–40 % with water of controlled salt content and temperature and covered with a hermetic lid. The chamber was used to study the characteristics of aerosols produced by bursting bubbles under different conditions. In line with previous findings, the sea spray aerosol production was shown to depend
linearly on the surface area covered by the bubbles, which in turn is a
near-linear function of the air discharge through the water. Observed
dependencies of the aerosol size spectra and particle fluxes on water
salinity and temperature, being qualitatively comparable with the previous
experiments, substantially refined the existing parameterizations. In
particular, the bubble size was practically independent from the air
discharge through the water body, except in the case of very small flows. Also, the
dependence of aerosol spectrum and amount on salinity was much weaker than
suggested in some previous experiments. The temperature dependence, to the
contrary, was significant and consistent, with a transition in the spectrum
shape at ∼ 10 ∘C. Theoretical analysis based on the
basic conservation laws supported the main results of the experiments but
also highlighted the need for a better understanding of the aerosol production
from a cold water surface.
Using On -Line Media “The Jakarta Post News Report” to Teach English to Government Program Students of STISIP NH Jambi
Authors: Hendrayani Santi 
Published: October 2022

The use of media such as on-line media “The Jakarta Post” newspaper can support teachers and students in teaching English process. It will improve the students ability, skill, knowledge, attitude , language content, reading and vocabulary by providing on-line media ”The Jakarta Post “newspaper . The purpose of using on-line media can be used by the students in the classroom to develop their skill and also used as the learning resources. Teaching English to Government Program has many problem. Commonly the students lack ability in English because of education background and at this program English as Compulsory Subject. At STISIP NH Jambi learning English as Compulsory Subject (MKDU) mata Kuliah Umum. Based on Curriculum the students must follow the English Subject. In teaching process many students lack of ability in English. The students knowledge as long as Junior and Senior High School give the impact of teaching process. The writer for this paper would like to share the information , experience and the way to teach English as a compulsory Subject . The existence of On-Line Media The Jakarta Post for the Government Program. The writer do the technique observation( do direct observation of the students as the object), interview, documentations and library research. The result of the research showed that: The continuously of learning English by using on-line media must be formed to reach the target of mastering English and the students of English Program must relay that the existence of English for Government program must mastery English to can compete in employment field.
Parasitological analysis of vegetables sold in supermarkets and free markets in the city of Taguatinga, Federal District, Brazil
Authors: Kennedy Souza Araújo Renato , Rios da Silva Adriano , Souza Nara Rúbia , Santos de Melo Krain 
Published: October 2022

Parasitosis are the most common diseases in the world, they are responsible for relevant negative consequences in the individuals´ health. The consumption of vegetables in Brazil and in the world is common due to their high nutritional value and they are recommended to be included in the population´s diet. Contaminations in vegetables are most often caused by irrigation water which is contaminated by feces, other forms of contamination are through organic manure containing fecal waste and the contact of vegetables with animals where they are grown. This research evaluated the contamination in vegetables with the purpose of warning the community about hygiene and the correct approach of food handling in order to prevent parasitic infections, contributing to people´s health. Samples were collected from supermarkets and farmers´ markets, where we obtained a total of 30 samples that were analyzed using Hoffman, centrifugation and slide reading´s techniques. In all samples, parasites were found. In six samples non-pathogenic amoebas were found, however this finding means that there was contamination from human or animal feces. And, in the other 24 samples, parasitic structures that cause damage to health were found. This work showed a high level of contamination of the vegetables that are consumed daily by the population and the diseases caused by food which are a concern for the public health. Contaminated vegetables are dangerous considering the transport of parasites that may generate human infections, therefore the importance to create public policies in order to avoid parasitic infections.
KEY WORDS: Parasitic infections; food contamination; parasitology; food parasitology;neglected diseases.