bluuebunny/crossref_metadata_2025_split huggingface dataset:
The individual and combined benefits of different non-equilibrium proofreading mechanisms
Authors: Mohr Adélaïde A. , Busiello Daniel M. , Zamuner Stefano , De Los Rios Paolo 
Published: July 2022

AbstractGenome duplication, transcription and translation are among many crucial cellular processes that need to be performed with high fidelity. However those extremely low error rates cannot be explained with simple equilibrium thermodynamic considerations. They instead require considering irreversible, energy consuming reactions in the overall mechanism. We develop here a model of substrates selection comprising energy consuming steps and which aims at selecting right substrates among wrong ones. With this model, we investigate the impact of energy consumption on the accuracy and the speed of the selection, as well as different selection strategies. The model presented here encompasses the classic kinetic proofreading scheme and a different mechanism whereby the rates of the energy consuming step are modulated by the nature of the substrate. We show that, in our framework, the fastest and most accurate selection strategy relies on a combination of both mechanisms. A structurally and biochemically informed coarse-grained description of real biological processes such as DNA replication and protein translation, traditionally used as examples of kinetic proofreading at work, shows that, as a matter of fact, a combination of both mechanisms explored here is exploited.
A Physcomitrella PIN protein acts in spermatogenesis and sporophyte retention
Authors: Lüth Volker M. , Rempfer Christine , van Gessel Nico , Herzog Oliver , Hanser Melanie , Braun Marion , Decker Eva L. , Reski Ralf 
Published: July 2022

SummaryThe auxin efflux PIN-FORMED (PIN) proteins are conserved in all land plants and important players in plant development. In the moss Physcomitrella (Physcomitrium patens) three canonical PINs (PpPINA-C) are expressed in the leafy shoot (gametophore). PpPINA and PpPINB show functional activity in vegetative growth and sporophyte development. Here, we examined the role of PpPINC in the life cycle of Physcomitrella.We established reporter and knockout lines for PpPINC and analysed vegetative and reproductive tissues using microscopy and transcriptomic sequencing of moss gametangia.PpPINC is expressed in immature leaves, mature gametangia and during sporophyte development. The sperm cells (spermatozoids) ofpinC knockout mutants exhibit increased motility and an altered flagella phenotype. Further, thepinC mutants have a higher portion of differentially expressed genes (DEGs) related to spermatogenesis, increased fertility, and an increased abortion rate of premeiotic sporophytes.Here, we show that PpPINC is important for spermatogenesis and sporophyte retention. We propose an evolutionary conserved way of polar growth during early moss embryo development and sporophyte attachment to the gametophore, while suggesting the mechanical function in sporophyte retention of a ring structure, the Lorch ring.
Specialty beers market: a comparative study of producers and consumers behavior
Authors: Haddad Felipe Furtini , Ribeiro Ana Paula Lima , Vieira Kelly Carvalho , Pereira Rafaela Corrêa , Carneiro João de Deus Souza 
Published: July 2022

PurposeThis study aimed to identify, with producers of specialty beers (SBs), producers' perceptions regarding the consumers, besides analyzing the consumer's behavior of SBs regarding consumers' preferences, perceptions and determining buying factors.Design/methodology/approachIn the qualitative analysis, interviews were performed with 14 professionals from the SB industry. In the quantitative study, 301 consumers of SB answered a questionnaire about preferences, perception and determining buying factors of special beer. Techniques such as content analysis, frequency analysis, cross-tabulation and hierarchical cluster analysis were used in this study.FindingsThe study demonstrated an important convergence in the perceptions of producers about consumers and the real behavior of SB consumers, mainly on factors of beer packaging, label, style and price. Those respondents consuming just SB were characterized by having higher income, frequency and time of beer consumption and willingness to pay more for the product. Cluster analysis allowed to segment respondents into three groups: (1) beginners in the universe of SBs who also drink commercial beers; (2) regular consumers willing to pay more for SB and (3) legitimate consumers of SB averse to commercial beer.Practical implicationsThere are practical implications in this study such as new products development and assertive creation of labels and packaging for special beers.Social implicationsThere are social implications in this study such as the convergence between industry professionals and consumers.Originality/valueBy addressing professionals and consumers, this study generated scientific information and knowledge to assist the specialty brewing industry in developing new products and defining marketing strategies as well as creating actions for bringing producers and consumers closer together to benefit both parties.
Brand hate: a literature review and future research agenda
Authors: Aziz Rahila , Rahman Zillur 
Published: July 2022

Purpose
A conceptual confusion has evolved in brand hate (BH) research mainly due to multiple conceptualizations, models and constructs in the field. As such, there is an urgent need to bring these insights together for a holistic understanding of research in BH, fostering its growth. This paper aims to fill this theoretical gap by bringing together the field of BH and delineating opportunities for further research.

Design/methodology/approach
A systematic literature review was conducted for a period of about two decades, from 1998 to August 2021. The authors included the English articles published in peer-reviewed academic journals with full texts relevant to this study, leading to a usable sample of 55 articles.

Findings
The authors’ findings reveal that the literature has inadequately distinguished BH as emotion and relationship, while the theoretical domain used to explore BH remains largely dominated by the psychology literature. Furthermore, BH research has primarily focused on services, with little distinction made between hatred across product and service context, with most studies set in developed countries. The authors further identify the need to investigate boundary conditions influencing BH and develop a more robust measure of BH to capture its dynamic facet.

Research limitations/implications
By presenting a comprehensive and up-to-date overview of the research in BH and highlighting the future research avenues, this study is believed to spur scholarly research and serve as a valuable tool for the researchers in advancing the research in BH.

Practical implications
Analysis of determinants and antecedents of BH provide managers an opportunity to nip the evil in the bud by preventing such situations that may lead to BH. Furthermore, insights into different BH consequences and boundary conditions allow brand managers to devise appropriate strategies to mitigate adverse reactions and foster positive consumer–brand relationships.

Originality/value
This study provides a thorough analysis of the current state of BH research in one place and draws a road map for scholars to further the research in this area.
How to enhance supply chain resilience: a logistics approach
Authors: Song Malin , Ma Xiaowei , Zhao Xin , Zhang Liangliang 
Published: July 2022

PurposeLogistics capability is an important enabler of supply chain resilience (SCR). However, few studies have analyzed the underlying influence mechanism of logistics capability on SCR in extreme conditions, such as those of the COVID-19 pandemic. The purpose of this study is to increase understanding of the role of logistics capabilities in constituting a resilient supply chain.Design/methodology/approachDrawing upon the dynamic capability perspective and contingency theory, the proposed conceptual framework aims to demonstrate the relationship between a firm's logistics capabilities and SCR. Furthermore, the conceptual framework is illustrated by empirical evidence from a case study of a Chinese manufacturing company, which focuses on extracting practical lessons from the COVID-19 pandemic.FindingsThe findings suggest that digitalization, innovativeness, and modularization comprise potential mediating pathways for firm logistics capability to affect SCR and government policies, risk management culture, trust and cooperation moderate the effect positively. The potential associations are identified and elucidated by detecting the corresponding strategies and practices of a Chinese manufacturer that performed well amid the COVID-19 pandemic.Practical implicationsThis study provides specific guidelines for logistics managers to enhance SCR during the COVID-19 pandemic. Seeing SCR as a dynamic capability, the framework is also instructive for manufacturers, supply chain members, and policymakers to achieve the sustained competitive advantage of supply chains.Originality/valueThe findings expand the understanding of enhancing SCR in a logistics approach. The empirical validation of propositions in the case study reveals a new vista for research on SCR.
“Unus pro omnibus, omnes pro uno”: understanding unauthorised file sharing in online communities from a public goods contribution perspective
Authors: Shao Xiuyan , Jiang Hemin , Siponen Mikko , Cao Cong , Huang Xiaohua 
Published: July 2022

PurposeUnauthorised file sharing (UFS) in online communities (OCs) is a major intellectual property concern. Researchers have traditionally viewed UFS as digital piracy and have suggested that deterrents, such as legal actions, should be in place. However, previous research has not considered the OC context and cannot explain why OC members share unauthorised files even when there is legislation against this in place. In OCs, UFS exhibits features of public goods contribution. Therefore, the authors claim that public goods contribution motivations can provide a compelling explanation for UFS in OCs.Design/methodology/approachThe authors propose a theoretical model in which two egoistic public goods contribution motivations (namely, warm-glow giving and demand for resources) are tested alongside motivations informed by the sanctions described by deterrence theory, a theory widely used within the digital piracy perspective.FindingsThe authors find that warm glow and demand for resources are positively related to UFS in OCs; the effect of warm glow is moderated by users' attachment to OCs. Importantly, the results suggest that although sanctions significantly predict UFS, the effect of sanctions on UFS becomes insignificant in the presence of warm glow, demand for resources and attachment.Originality/valueThe study offers new insights into why users engage in UFS and highlights that public goods contribution should be taken into account in developing anti-piracy policies and practices.
Drivers of foreign direct investment: new evidence from West African regions
Authors: Korsah Emmanuel , Amanamah Richmell Baaba , Gyimah Prince 
Published: July 2022

PurposeThis paper aims to empirically investigate the factors attracting foreign direct investment (FDI) inflows into emerging economies.Design/methodology/approachThis study uses secondary data from the World Bank and the Global State of Democracy Indices of 16 West African countries (WACs) over the period from 1989 to 2018. Fixed- and random-effects econometric regression models are used to assess the nexus between 12 macroeconomic indicators (including political risk and cultural factors) and FDI inflows into WACs.FindingsThe critical drivers of FDI inflows into WACs are the richness of natural resources, market size or gross domestic product (GDP), imports and exports of goods and services, trade openness and the currency's strength as measured by the exchange rate. The result also reveals that French-speaking countries attract more FDI than other English-speaking countries. The previously cited determinants of FDI, such as infrastructural development, inflation, tax and political stability, are insignificant in determining FDI inflows into WACs.Originality/valueThis study uncovers the critical drivers explaining the FDI inflows into WACs, where FDI accounts for 39% of external finance. The study's contribution is that Francophone WACs attract more FDI than Anglophone WACs. The most important drivers of FDI are abundant natural resources, GDP, imports, exports, trade openness and exchange rate.
The effect of superfine grinding on physicochemical properties of three kinds of mushroom powder
Authors: Gong Pin , Huang Zihan , Guo Yuxi , Wang Xiaojuan , Yue Shan , Yang Wenjuan , Chen Fuxin , Chang Xiangna , Chen Lei 
Published: July 2022

AbstractThe effects of superfine grinding on apparent structure, physicochemical properties, and functional characteristics of three kinds of mushroom (Lentinus edodes, Hericium erinaceus, and Cordyceps militaris) powders were investigated. Coarse and 100‐mesh powders of the mushrooms were prepared by common grinding, while a superfine powder was obtained by superfine grinding. By comparing the mushrooms before and after grinding, it was found that the mushroom fines did not produce new chemical groups but increased crystallinity. The results of the physicochemical properties revealed that the fines became less fluid after grinding. The protein content and solubility increased as the particle size decreased. The water and oil holding capacity, glucose binding capacity, cation exchange capacity, and antioxidant activity of the mushroom fines increased after grinding. This study provides a theoretical basis for the development process of edible mushroom food, as well as new ideas for the development of edible mushrooms.
Did conversion to thoracotomy during thoracoscopic lobectomy increase post‐operative complications and prejudice survival? Results of best evidence topic analysis
Authors: Fiorelli Alfonso , Forte Stefano , Santini Mario , Petersen René Horsleben , Fang Wentao 
Published: July 2022

AbstractThe potential complications related to unplanned conversion to thoracotomy remains a major concern in thoracoscopic lobectomy and may limit the wide adoption of this strategy. We reviewed the literature from 1990 until February 2022, analyzing all papers comparing successful thoracoscopic lobectomy versus converted thoracoscopic lobectomy and/or upfront thoracotomy lobectomy to establish whether unplanned conversion negatively affected outcomes. Thirteen studies provided the most applicable evidence to evaluate this issue. Conversion to thoracotomy was reported to occur in up to 23% of cases (range, 5%–16%). Vascular injury, calcified lymph nodes, and dense adhesions were the most common reasons for conversion. Converted thoracoscopic lobectomy compared to successful thoracoscopic lobectomy was associated with longer operative time and hospital stay in all studies, with higher postoperative complication rates in seven studies, and with higher perioperative mortality rates in four studies. No significant differences were found between converted thoracoscopic lobectomy and upfront thoracotomy lobectomy. Five studies evaluated long‐term survival, and in all papers conversion did not prejudice survival. Surgeons should not fear unplanned conversion during thoracoscopic lobectomy, but to avoid unexpected conversion that may negatively impact surgical outcome, a careful selection of patients is recommended–especially for frail patients.
A systematic method for hypothesis synthesis and conceptual model development
Authors: Grames Eliza M. , Schwartz Danielle , Elphick Chris S. 
Published: July 2022

Abstract

Conceptual models are necessary to synthesize what is known about a topic, identify gaps in knowledge and improve understanding. The process of developing conceptual models that summarize the literature using ad hoc approaches has high potential to be incomplete due to the challenges of tracking information and hypotheses across the literature.

We present a novel, systematic approach to conceptual model development through qualitative synthesis and graphical analysis of hypotheses already present in the scientific literature. Our approach has five stages: researchers explicitly define the scope of the question, conduct a systematic review, extract hypotheses from prior studies, assemble hypotheses into a single network model and analyse trends in the model through network analysis.

The resulting network can be analysed to identify shifts in thinking over time, variation in the application of ideas over different axes of investigation (e.g. geography, taxonomy, ecosystem type) and the most important hypotheses based on the network structure. To illustrate the approach, we present examples from a case study that applied the method to synthesize decades of research on the effects of forest fragmentation on birds.

This approach can be used to synthesize scientific thinking across any field of research, guide future research to fill knowledge gaps efficiently and help researchers systematically build conceptual models representing alternative hypotheses.
How is illiquidity priced in the Chinese stock market?
Authors: Liu Jun , Wu Kai , Jiang Fuwei , Shen Zhiqi 
Published: July 2022

AbstractThis study investigates the liquidity premium in the Chinese stock market. We found that the expected stock returns increase monotonically with the quintile sort on characteristic liquidity with descending patterns. The characteristic liquidity premium ranges from 0.82% to 1.28% per month, which is much higher than that of their US counterparts. Moreover, our multivariate decomposition approach highlights that characteristic illiquidity premiums can be explained mainly by size, idiosyncratic volatility and momentum. The net systematic liquidity premium reaches 0.84% per month, driven mainly by commonality beta. The finding shows that a liquidity‐based strategy forecasts cross‐section and time‐series expected returns.
Decreased severity of COVID‐19 in vaccinated pregnant individuals during predominance of different SARS‐CoV‐2 variants
Authors: Eid Joe , Abdelwahab Mahmoud , Williams Hayley , Caplan Madeleine , Hajmurad Sema , Venkatesh Kartik K , Costantine Maged M. , Rood Kara M. 
Published: July 2022

AbstractProblemSince the start of the pandemic, Pregnant individuals have been disproportionately affected by the severe acute respiratory syndrome coronavirus 2. Vaccination has been shown to be protective against severe disease. However, data on effectiveness of vaccine in reducing disease severity are limited in pregnant individuals who later developed COVID‐19.Method of studyThis is a single academic center retrospective cohort study of pregnant individuals who tested positive for COVID‐19 from December 2020 through January 2022. The cohort was divided into two groups based on vaccination status. The primary outcome of our study was progression to severe or critical disease. A secondary analysis was performed based on the timeframes of predominance of different variants of SARS‐CoV‐2, to determine whether the effect of vaccination was different during these epochs.ResultsOur cohort included 472 patients among which 125 (26.5%) were vaccinated and 347 were unvaccinated. None of the patients in the vaccinated group who later developed COVID‐19 progressed to severe or critical disease compared to 7.2% in the unvaccinated one (p < .01). Similarly, after adjusting for medical comorbidities, obesity, receipt of monoclonal antibodies, and trimester at diagnosis, vaccinated individuals who later developed COVID‐19 were less likely to be admitted to the hospital (1.6% vs. 14.7%, aOR .14, 95% CI .22–.47) compared with unvaccinated ones.ConclusionVaccination against SARS‐CoV‐2 in pregnant individuals who later develop a breakthrough infection, is associated with decreased progression to severe or critical COVID‐19, and need for hospital and ICU admissions. Vaccination is specifically effective during the predominance of the more severe Delta variant.
Morphological aspects of the digestive tract of insectivorous bats of the species Molossus rufus (E. Geoffroy, 1805)
Authors: Geronimo Edson , Favetta Paula M. , Palin Gustavo C. , Trindade Wesley A. , Serenini Grazielli F. , Martins Lisiane A. , Otutumi Luciana K. , Germano Ricardo M. 
Published: July 2022

AbstractFive male specimens of the species Molossus rufus from north‐western Parana were captured, identified, packaged and transported to the laboratory for weighing and later euthanasia with isoflurane. They were laparatomized for evaluation of macroscopic characteristics and the digestive tube segments were collected for fixation in 10% neutral formalin for histological processing, after 48 h of fixation. Macroscopically, the digestive tube had an oesophageal segment in the abdominal cavity, with a J‐shaped saccular stomach, in addition to a small intestine divided into duodenum, jejunum‐ileum and terminal ileum. In the large intestine, an organ dilatation was observed from the small intestine with a one‐way oral‐aboral ending in the anus, which was called the descending colon. Morphological similarity of the walls of all segments with those of other mammals was observed; however, it presented some peculiarities such as the absence of oesophageal glands, Brunner in the intestine, cecum and appendages. The anatomical disposition and tissue pattern were similar to that found in other insectivorous species. The adaptations of the digestive tube of this species are possibly due to the insectivorous feeding habits, which can be impacted due to anthropic actions in foraging environments.