bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comprehensive Literature Review of Allergic Conjunctivitis
Authors: Cahyana Nugraha Wahyu 
Published: April 2022

Allergic disease is a complex disease caused by a combination of genetic and environmental factors. Allergic diseases are on the rise, affecting about 30% to 40% of the world's population. In addition to a decrease in quality of life, this disease can affect thesocial and economic. This study aims to determine the concept of allergic conjunctivitis and its current management. Results: Allergic conjunctivitis is an inflammatory response of the conjunctiva to allergens such as pollen, environmental antigens (eg dust), and animal dander. Conclusion: Allergic diseases can be managed strategically, both non-pharmacologically and pharmacologically. Pharmacological use is usually preferred when non-pharmacological methods prove ineffective or insufficient in reducing allergy symptoms. Topical therapy consists of combination drugs such as antihistamines and vasoconstrictors, or antihistamines with mast cell stabilizing properties. The first are vasoconstrictors that target eye redness and antihistamines that target allergy symptoms.
Keywords: Allergic Conjunctivitis, Concept, Drugs
Determination of α-Amylase Inhibitory potential of leaf extracts of Rhododendron arboreum Sm. and Rhododendron campanulatum D. Don
Authors: Prakash Ved 
Published: April 2022

The biological activity of plant-derived substances/metabolites may be considered as a source of new anti-enzyme drugs. Therefore, traditional Indian plants i.e. Rhododendron arboreum and R. campanulatum which are commonly used as remedies to control different diseases were screened to discover possible plant-derived α-amylase inhibitors. In the present investigation, inhibitory effects of leaf extracts of Rhododendron arboreum and R. campanulatum were determined against porcine α-amylase at a concentration range of 0.2-1.0 mg/mL. R. arboreum displayed 51.10, 44.00 and 35.40% inhibition at a concentration of 1 mg/mL for methanol, acetone and aqueous leaf extracts respectively. On the other hand, R. campanulatum showed 21.15, 18.25 and 15.85% α-amylase inhibition for methanol, acetone and aqueous extracts respectively at 1 mg/mL. The inhibitory activity increased altogether with increasing concentration of each plant extract. The results further indicated that methanol extracts of medicinal plants exhibited maximum inhibitory effects than other solvent (acetone, methanol) extracts.
Keywords: Rhododendron arboreum, Rhododendron campanulatum, porcine α-Amylase, Leaf extracts, Inhibition
Pharmaceutical Process Validation: A Review
Authors: Karthick C , Kathiresan K 
Published: April 2022

Pharmaceutical industries are in now their peak period. There is a need to ensure that pharmaceutical process validations are being done so well and results we obtain is reproducible. Results simply ensure product items consistency. These validations must be done in such a way that final product satisfies all of requirements, is very necessary in pharmaceutical field. Whatever will be the product or whatever will be the protocols, important prerequisite is Quality. Process validation signifies the values of analytical tools, analytical procedures, objective measures and it gives attention towards Knowledge, Detection and control on variabilities So as to assure quality throughout the life cycle of product. The object of this article is to explain the enormous utilities of process validation and their need, methods. This process validation assures the delivery of product just like predetermined. Without the process validation one cannot expect the precision in results.
Keywords: PV- Process validation, CV- Concurrent validation, RV- Retrospective validation
RELIABILITY AND SEX DIFFERENCES OF CHOICE VISUAL-MOTOR REACTION TIME AND FORCE CHARACTERISTICS OF NECK MUSCLES USING A NOVEL TEST
Authors: Nagai Takashi , Shilaty Nathan D , Chang Ryan W. , Keller Valerie , Stiennon Sean T , Wong Hanwen , Stuart Michael J , Krause David A 
Published: April 2022

IntroductionSensorimotor characteristics such as visual-motor reaction time (VMRT), peak force, and rate of force development (RFD) of the neck muscles play an important role in sports-related concussions (SRC). The purpose of this study was to establish reliability and sex differences of neck-specific VMRT and force characteristics of neck muscles using a novel test.
MethodsThis is a two-part study. A total of 15 subjects and 49 subjects participated to examine test–retest reliability and sex differences in multidirectional choice VMRT and peak force and RFD values, respectively.
ResultsReliability was moderate for VMRT (Intraclass Correlation Coefficient, ICC = 0.406–0.624) and moderate to excellent for peak force and RFD (ICC = 0.443–0.948). Females had significantly slower VMRT (P < 0.001–0.012), while no sex differences were found in peak force and RFD (P = 0.079–0.763).
DiscussionFuture investigations should incorporate these characteristics during baseline testing and examine if they can be identified as prospective risk factors of SRC.
Obstructive apnea syndrome as a risk factor for the development of postoperative complications in obese patients
Authors: Skvortsova R. D. , Pavlova V. А. , Anisimova K. A. , Popova K. A. , Obukhova A. A. , Kazachenko A. A. , Rabik Yu. D. , Balandov S. G. , Vasilevsky D. I. , Kulikov A. N. 
Published: April 2022

Introduction. Early detection of patients with obstructive sleep apnea syndrome (OSAS) using preoperative screening is necessary to reduce risks in the perioperative period.The objective was to assess the effect of OSAS on the perioperative management of patients.Methods and materials. 54 patients with a BMI of more than 30 kg/m2 were examined, for whom a bariatric operation was performed as planned. Before the operation, all patients underwent respiratory polygraph with the calculation of the apnea/ hypopnea index (AHI), mean saturation (SpO2 m) during sleep and spirometry.Results. Patients were divided into 2 groups according to AHI: gr. 1 (n=33) with AHI<15/hour, OSAS, gr. 2 (n=21) with a AHI ≥15/hour. In gr. 2 VC and FVC should be significantly lower than in gr. 1 (p<0.01). A significant decrease in SpO2 m was noted (p<0.001). On the first day after the operation, there was an increase in pCO2 of arterial blood in gr. 2, in comparison with gr. 1 (p<0.05).Conclusions. OSAS can be considered as an independent adverse risk factor for potential perioperative complications. Early detection of OSAS will reduce the risks of postoperative complications.
Single-stage and two-stage approaches in the management of acute biliary pancreatitis: indications and contraindications
Authors: Nikitina T. O. , Korolkov A. U. , Smirnov A. A. , Popov D. N. , Saadylaeva M. M. , Bagnenko S. F. 
Published: April 2022

The objective was to improve the management of patients with acute biliary pancreatitis against the background of cholecystocholedocholithiasis.Methods and materials. 133 patients with acute biliary pancreatitis against the background of cholecystocholedocholithiasis were treated between 2017 and 2021 years. Patients suffering from mild and moderately severe acute biliary pancreatitis underwent single-step (laparoscopic cholecystectomy with endoscopic papillosphincterotomy) or two-step (endoscopic papillosphincterotomy with delayed laparoscopic cholecystectomy) surgical interventions. Patients with severe acute pancreatitis underwent endoscopic papillosphincterotomy with or without common bile duct and pancreatic duct stenting. The comparative analysis was made to estimate the efficiency of different surgical interventions in different groups of patients.Results. Patients with mild or moderately severe acute biliary pancreatitis showed better outcomes after single-step surgical intervention. Patients with severe acute biliary pancreatitis – after endoscopic papillosphincterotomy with common bile duct and pancreatic duct stenting.Conclusion. Single-step surgical interventions (laparoscopic cholecystectomy with endoscopic papillosphincterotomy) are shown for patients with mild or moderately severe acute biliary pancreatitis, because this approach helps to preserve the complications, specific for two-step interventions. The single-step approach authentically helps to decrease the duration of hospital stay and reduce treatment costs. The two-step approach is shown for patients with severe acute biliary pancreatitis, but endoscopic papillosphincterotomy with lithoextraction should be supplemented by common bile duct and pancreatic duct stenting, in order to reduce the number of complications associated with delayed cholecystectomy.
Pengaruh Ease of Use, Trust, dan Privacy Concern terhadap Repurchase Intention pada Situs Jual Beli Online Bukalapak
Authors: Buntarman Calvin , Rodhiah Rodhiah 
Published: April 2022

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh ease of use, trust dan privacy concern terhadap repurchase intention pada situs jual beli online Bukalapak. Populasi dari penelitian ini adalah pengguna Marketplace Bukalapak yang sudah pernah bertransaksi di Bukalapak minimal 4 kali. Penelitian ini menggunakan metode non probability. Sampel dipilih menggunakan metode purposive sampling berjumlah 100 responden yang sudah pernah berbelanja di marketplace bukalapak minimal 4 kali. Teknik pengumpulan data menggunakan kuesioner yang disebarkan secara online malalui google form. Penelitian ini menggunakan teknik analisis structural equation modeling (SEM) dengan menggunakan software SMART PLS 3 untuk mengolah data. Hasil penelitian ini menunjukkan bahwa ease of use berpengaruh positif dan signifikan terhadap repurchase intention, trust berpengaruh positif dan signfikan terhadap repurchase intention dan privacy concern berpengaruh positif dan signifikan terhadap repurchase intention. The purpose of this study was to determine the effect of ease of use, trust and privacy on repurchase intentions on the online buying and selling site Bukalapak. Data collection techniques were carried out by distributing questionnaires using a Likert scale of 1-5. Data collection techniques used questionnaires distributed online via google form. The sample selected using the purposive sampling method was 100 respondents who had shopped at the Bukalapak marketplace 4 times. This study uses structural equation modeling (SEM) analysis techniques using SMART PLS 3 software to process data. The results of this study indicate that ease of use has a positive effect on repurchase intentions, trust has a positive effect on repurchase intentions and attention to privacy has a significant effect on repurchase intentions.
Pengaruh Entrepreneurial Attitude Orientation dan Latar Belakang Pribadi terhadap Minat Berwirausaha
Authors: Teddy Daniel Immanuel , Nuringsih Kartika 
Published: April 2022

Untuk mengatasi masalah pengangguran, perlu dikembangkan beberapa solusi, salah satunya adalah mendukung kegiatan kewirausahaan mikro terutama pada kalangan generasi muda. Pemerintah mempunyai peran penting yang mempengaruhi terciptanya kewirausahaan pada masyarakat dengan memasukkan kurikulum kewirausahaan dalam perguruan tinggi. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh dari lingkungan keluarga dan motivasi terhadap minat berwirausaha mahasiswa di Jakarta Barat. Metode penelitian ini menggunakan metode kuantitatif dengan menggunakan sampel yang berjumlah 100 yang diambil dari mahasiswa di Jakarta Barat, penelitian ini menggunakan skala likert dan analisis menggunakan PLS sebagai alat bantu dalam melakukan pengolahan data. Hasil penelitian menunjukkan bahwa latar belakang pribadi berpengaruh negatif dan tidak signifikan terhadap minat berwirausaha, entrepreneurial attitude berpengaruh positif dan signifikan terhadap minat berwirausaha dan entrepreneurial orientation berpengaruh positif dan signifikan terhadap minat berwirausaha. To overcome the existing unemployment problem, it is necessary to develop several solutions, one of which is by supporting micro-entrepreneurial activities, especially among the younger generation. The government has an important role in influencing the creation of entrepreneurship in society by including the entrepreneurship curriculum in universities. The purpose of this study was to determine the effect of family environment and motivation on entrepreneurial interest of students in West Jakarta. This research method uses quantitative methods using a sample of 100 taken from students in West Jakarta, this study uses a Likert scale and analysis using PLS as a tool in data processing. The results showed that personal background had a negative and insignificant effect on interest in entrepreneurship, entrepreneurial attitude had a positive and significant effect on interest in entrepreneurship and entrepreneurial orientation had a positive and significant effect on interest in entrepreneurship.
Pengaruh Investment Opportunity, Capital Structure, dan Dividend Policy terhadap Firm Value pada Perusahaan LQ45 di Bursa Efek Indonesia
Authors: Frendy Frendy , Yusbardini Yusbardini 
Published: April 2022

Tujuan dari dilakukannya penelitian ini untuk mengetahui pengaruh dari investment opportunity, capital structure, dan dividend policy terhadap firm value pada perusahaan yang terdaftar dalam indeks LQ45 di Bursa Efek Indonesia (BEI) periode 2015-2019. Dengan menggunakan metode purposive sampling pada pemilihan sampel, didapatkan sebanyak 23 perusahaan yang telah memenuhi kriteria yang telah ditentukan. Metode yang akan digunakan pada penelitian ini berupa regresi linier berganda dengan bantuan dari program Eviews 10 dalam pengolahan data yang ada. Melalui pengolahan data yang ada, didapatkan hasil investment opportunity memiliki pengaruh yang positif dan tidak signifikan terhadap firm value, capital structure memiliki pengaruh yang positif dan tidak signifikan terhadap firm value, dan dividend policy memiliki pengaruh yang positif dan signifikan terhadap firm value. The aims of this study is to determine the effect of investment opportunities, capital structure, and dividend policy on firm value in companies listed in the LQ45 index on the Indonesia Stock Exchange (IDX) for the period of 2015-2019. By using purposive sampling method in the selection of samples, obtained 23 companies that have met the criteria that have been determined. The method that will be used in this study is multiple regression analysis which is processed with Eviews 10 software in processing data. Through the processing of the data, it is found that investment opportunities have a positive and insignificant effect on firm value, capital structure has a positive and insignificant effect on firm value, and dividend policy has a positive and significant effect on firm value.
Pengaruh Financial Knowledge, Financial Self-Efficacy, dan Risk Perception terhadap Investment Intention di Pasar Saham
Authors: Florencia Irene , Arifin Agus Zainul 
Published: April 2022

Tujuan penelitian ini adalah untuk menganalisis apakah 1) pengetahuan keuangan dapat mempengaruhi niat investasi; 2) efikasi diri dapat mempengaruhi niat investasi; 3) persepsi risiko dapat mempengaruhi niat investasi. Sampel diperoleh dengan metode purposive sampling dengan total 283 responden di Jabodetabek dan dianalisa dengan SmartPLS 3.0.0. Hasil penelitian ini menunjukkan bahwa pengetahuan keuangan, efikasi diri, dan persepsi risiko memiliki pengaruh yang signifikan terhadap niat investasi. The purpose of this study is to analyze whether 1) financial knowledge can affect investment intentions; 2) self-efficacy can affect investment intentions; 3) the perception of risk can affect investment intentions. The sample was collected by purposive sampling method with a total of 283 respondents in JABODETABEK and analyzed using SmartPLS 3.0.0. The results of this study show that financial knowledge, self-efficacy, and risk perception have a significant influence on investment intentions.
Pengaruh Pendidikan Kewirausahaan dan Efikasi Diri Kewirausahaan terhadap Intensi Berwirausaha: Sikap Kewirausahaan sebagai Variabel Mediasi
Authors: Natasha Jocelin , Puspitowati Ida 
Published: April 2022

Penelitian ini bertujuan untuk menguji secara empiris pengaruh dari Pendidikan Kewirausahaan dan Efikasi Diri terhadap Intensi Berwirausaha dengan Sikap Kewirausahaan sebagai variabel mediasi. Populasi dari penelitian ini sebesar 150 responden yang merupakan Mahasiswa Fakultas Ekonomi dan Bisnis Universitas Tarumanagara. Teknik pengumpulan data dilakukan dengan penyebaran kuesioner melalui Google Form dan diolah menggunakan software SmartPLS-SEM versi 3.3.3. Metode pengambilan sampel yang digunakan dalam penelitian adalah dengan Non-Probability Sampling melalui Convenience Sampling. Hasil dari penelitian ini menunjukkan bahwa Pendidikan Kewirausahaan dan Efikasi Diri berpengaruh positif dan signifikan terhadap Intensi Berwirausaha. Pendidikan Kewirausahaan dan Efikasi Diri berpengaruh positif dan signifikan terhadap Sikap Kewirausahaan. Demikian juga Sikap Kewirausahaan sebagai variabel mediasi berpengaruh positif dan signifikan mampu memediasi hubungan dari Pendidikan Kewirausahaan dan Efikasi Diri terhadap Sikap Kewirausahaan. The purpose of this research is to empirically examine the effect of Entrepreneurial Education and Entrepreneurial Self Efficacy on Entrepreneurial Intention with Entrepreneurial Attitude as a Mediation Variable. The population of this research is 150 respondents of Students on Faculty of Economics and Business, Universitas Tarumanagara. Data are collected by using Google Form questionnaires and processed using SmartPLS-SEM software version 3.3.3. The sampling method used in this research is Non-Probability Sampling technique with Convenience Sampling. The results of this study indicate that Entrepreneurial Education and Entrepreneurial Self Efficacy have a positive and significant effect on Entrepreneurial Intention, Entrepreneurial Education and Entrepreneurial Self Efficacy have a positive and significant effect on Entrepreneurial Attitude, and Entrepreneurial Attitude as a mediating variable has a positive and significant effect and able to mediate the relationship between Entrepreneurial Education and Entrepreneurial Self. Efficacy towards Entrepreneurial Intention.
Pengaruh Brand Experience, Brand Personality, dan Brand Satisfication terhadap Brand Loyalty Produk Sepatu Compass pada Generasi Z di Jakarta
Authors: Janitra Renardi , Tjokrosaputro Miharni 
Published: April 2022

Tujuan dari penelitian ini adalah untuk menguji apakah pengalaman merek, kepuasan merek, kepribadian merek dapat mempengaruhi loyalitas merek pada brand sepatu Compass pada generasi Z di Jakarta. Jumlah sampel yang digunakan dalam penelitian ini sebanyak 202 responden pelanggan sepatu Compass. Jenis penelitian ini adalah penelitian deskriptif. Pengumpulan data pada penelitian ini menggunakan cross-sectional. Penelitian ini menggunakan teknik pengambilan sampel non-probability sampling dengan menggunakan metode convenience sampling. Metode analisis data yang digunakan dalam penelitian ini dengan menggunakan software SmartPLS versi 3.32. Hasil dari penelitian ini menunjukkan pengalaman merek secara positif dapat digunakan untuk mempengaruhi loyalitas merek sepatu Compass pada generasi Z di Jakarta, kepuasan merek secara positif dapat digunakan untuk mempengaruhi loyalitas merek sepatu Compass pada generasi Z di Jakarta dan kepribadian merek secara positif dapat digunakan untuk mempengaruhi loyalitas merek pada generasi Z di Jakarta. The purpose of this study is to examine whether brand experience, brand satisfaction, and brand personality on brand loyalty for compass shoes product at generation Z in Jakarta. The number of samples used in this study were 202 compass shoes customer respondents. This type of research is descriptive research. The data collection in this study used a cross sectional method. This study uses a non-probability sampling technique with a convenience sampling method. The data analysis method used in this study is the Smart Partial Least Square (PLS) software version 3.32. The results of this study indicate that positive brand experience can be used to effect Compass brand loyalty at generation Z in Jakarta, Brand Satisfaction can be used positively to effect Compass brand loyalty at generation Z in Jakarta, Brand Personality can be used positiv to effect Compass brand personality at generation Z in Jakarta.
Pengaruh Profitability, Non Performing Loan, dan Firm Size terhadap Corporate Value
Authors: Wijaya Sharon Angelina , Ruslim Herman 
Published: April 2022

Tujuan dari penelitian ini adalah untuk menguji pengaruh profitabilitas, non performing loan dan ukuran perusahaan terhadap nilai perusahaan secara simultan dan parsial. Sampel pada penelitian ini adalah perusahaan perbankan yang tercatat di Bursa Efek Indonesia (BEI) pada tahun 2018-2020. Teknik analisis data menggunakan analisis regresi berganda, uji-F, uji-t dan uji koefisien determinasi. Sampel dipilih dengan metode purposive sampling yang berjumlah 24 perusahaan. Analisis data menggunakan program Eviews 10. Secara simultan, menunjukkan profitabilitas, non performing loan dan ukuran perusahaan berpengaruh terhadap nilai perusahaan. Secara parsial, menunjukkan profitabilitas berpengaruh terhadap nilai perusahaan, non performing loan tidak berpengaruh terhadap nilai perusahaan, ukuran perusahaan berpengaruh terhadap nilai perusahaan. The purpose of this research is to analyze the influence of profitability, non performing loan and firm size on corporate value simultaneously and partially. The population of this research are the listed banking firms in the Indonesia Stock Exchange (IDX) from 2018-2020 period. The data analysis technique used multiple regression analysis, F-test, t-test and coefficient determination test. Sample was selected using purposive sampling method amounted to 24 firms. Data processed using Eviews 10 program. Simultaneously, the result of this study shows that profitability, non performing loan and firm size do affect corporate value. Partially, the result of this tudy shows that profitability does affect corporate value, non performing loan does not affect corporate value, firm size does affect corporate value.
Faktor-Faktor yang Mempengaruhi Kepuasan Kerja Karyawan Mini Plaza A di Kota X
Authors: Tanjung Silva Tasya , Turangan Joyce Angelique 
Published: April 2022

Penelitian ini bertujuan untuk mengetahui apakah lingkungan kerja, motivasi kerja dan kompensasi dapat mempengaruhi kepuasan kerja karyawan Mini Plaza A. Sampel penelitian adalah sebanyak 86 karyawan. Metode penelitian ini menggunakan SmartPLS dan dengan cara menyebarkan kuesioner melalui Google Form. Hasil dari penelitian ini adalah terdapat pengaruh positif dan signifikan lingkungan kerja, motivasi kerja dan kompensasi terhadap kepuasan kerja karyawan Mini Plaza A. This study aims to determine whether the work environment, work motivation and compensation can affect the job satisfaction of employees of Mini Plaza A. The research sample was 86 employees. This research method uses SmartPLS and by distributing questionnaires through Google Form. The result of this research is that there is a positive and significant effect of work environment, work motivation and compensation on job satisfaction of Mini Plaza A employees.