bluuebunny/crossref_metadata_2025_split huggingface dataset:
Environmental Uncertainty as a Moderator of Entrepreneurship Orientation and Innovation Capability during the Pandemic: A Case of Written Batik SMEs in Yogyakarta
Authors: Utomo Humam Santosa , Susanta Susanta 
Published: November 2022

Background: Written batik is one of Indonesia's cultural heritages that must be preserved. During the Covid-19 pandemic, written batik producers in Indonesia experienced increasing challenges due to the uncertainty of the business environment. Innovation is a solution to the problems faced by SMEs during a pandemic to survive. This study aims to examine the effect of entrepreneurship orientation on innovation capability. This study also examines the role of moderating environmental uncertainty in strengthening the effect of entrepreneurship orientation on innovation capability. Methods: The research was conducted at the centre of small and medium-sized batik companies Giriloyo, Bantul, Yogyakarta, Indonesia. Respondents of this study were 130 small and medium companies selected by random sampling. The questionnaire is used as a primary data collection tool. WarpPLS has been used to analyze the effect between variables in this study. Results: Entrepreneurship orientation is an important aspect in improving the innovation capabilities of SMEs. Environmental uncertainty during the COVID-19 pandemic has strengthened the effect of entrepreneurship orientation on innovation capabilities. Conclusions: The findings of this study indicate that entrepreneurship orientation has a significant effect on innovation capabilities. Environmental uncertainty significantly strengthens the effect of entrepreneurship orientation on innovation capability.
Psychosocial family-level mediators in the intergenerational transmission of trauma: Protocol for a systematic review and meta-analysis
Authors: Mew Emma J. , Nyhan Kate , Bonumwezi Jessica L. , Blas Vanessa , Gorman Hannah , Hennein Rachel , Quach Kevin , Shabanova Veronika , Hawley Nicola L. , Lowe Sarah R. 
Published: November 2022

IntroductionFamily-level psychosocial factors appear to play a critical role in mediating the intergenerational transmission of trauma; however, no review article has quantitatively synthesized causal mechanisms across a diversity of trauma types. This study aims to systematically consolidate the epidemiological research on family-level psychosocial mediators and moderators to ultimately produce causal diagram(s) of the intergenerational transmission of trauma.MethodsWe will identify epidemiological peer-reviewed publications, dissertations, and conference abstracts that measure the impact of at least one psychosocial family-level factor mediating or moderating the relationship between parental trauma exposure and a child mental health outcome. English, French, Kinyarwanda, and Spanish articles will be eligible. We will search MEDLINE, PsycINFO, PTSDpubs, Scopus, and ProQuest Dissertations and Theses and will conduct forward citation chaining of included documents. Two reviewers will perform screening independently. We will extract reported mediators, moderators, and relevant study characteristics for included studies. Findings will be presented using narrative syntheses, descriptive analyses, mediation meta-analyses, moderating meta-analyses, and causal diagram(s), where possible. We will perform a risk of bias assessment and will assess for publication bias.DiscussionThe development of evidence-based causal diagram(s) would provide more detailed understanding of the paths by which the psychological impacts of trauma can be transmitted intergenerationally at the family-level. This review could provide evidence to better support interventions that interrupt the cycle of intergenerational trauma.Trial registrationSystematic review registration:PROSPERO registration ID#CRD42021251053.
Training programs in preclinical studies. The example of pulmonary hypertension. Systematic review and meta-analysis
Authors: Jasińska-Stroschein Magdalena 
Published: November 2022

Background
Exercise and cardiopulmonary exercise testing are essential in the evaluation of physiological, biochemical, and molecular responses in the experimental studies on chronic diseases such as diabetes, heart failure and hypertension. The exercise tolerance and seem to be a valuable contribution to the experiments that are performed in animal models of pulmonary hypertension (PH), as well. The current survey uses detailed quantitative analyses to assess the advantages of exercise training programs performed in preclinical studies based on outcomes such as exercise capacity, cardiopulmonary hemodynamics, and mortality.

Methods
Articles were identified through search engines in the online electronic databases Pubmed/Medline, Web of Science following the PRISMA Protocol. Studies conducted between 1991 and 2022 without language restrictions were included in this study. Heterogeneity was assessed using the Cochrane Q-test and I2 test statistics. Subgroup analysis was employed with evidence of heterogeneity. Quality assessment was carried out using SYRCLE’s risk of bias tool for animal studies. Publication bias across studies was determined using the funnel plot and Egger’s regression test statistic.

Results
The available protocols typically included treadmill running, swimming, and voluntary wheel running with a different series of intensities, times and durations; these were also used in studies examining the efficacy of chronic training programs. In 66 interventions, PH induction reduced exercise endurance by half compared to healthy subjects, while exposure to tested medical agents normalized exercise capacity. The other 58 interventions demonstrated the advantages of various exercise training programs for PH. Induction of PH reduced exercise endurance by half compared to healthy subjects (R = 0.52; 0.48 − 0.55 95%CI; P<0.0001; I2 = 98.9%), while the exposure to tested medical agents normalized exercise capacity (R = 1.75; 1.61 − 1.91 95%CI; P<0.0001; I2 = 97.8%).

Conclusion
Despite a wide spectrum of study protocols to measure exercise endurance in animals with PH, there is a significant correlation between worsening of exercise-related parameters and PH development, manifested by alterations in haemodynamic and remodeling parameters. Familiarization with exercise, training program schedule, method used for PH induction, or detailed training parameters such as slope, exercise intensity or individualization, can influence the final outcome. This in turn can impact on the diversity and reproducibility of results being obtained in particular experimental studies.
The effects of environmental prenatal program on environmental health perception and behavior using internet-based intervention in South Korea: A non-randomized controlled study
Authors: Kim Hyun Kyoung , Jeong Geum Hee , Min Hye Young 
Published: November 2022

Purpose
This study aimed to develop and examine the effects of an internet-based intervention program on environmental perception and behavior among Korean pregnant women based on revised protection motivation theory.

Method
This study was a non-equivalent control group pre-post-test design. The experimental program consisted of prenatal education, reduction of fine dust, birth education, environmental health promotion, and postnatal management education using zoom video conferences. The face-to-face interventions were provided through regular prenatal classes at public health services for the control group. The total participant was 49 pregnant women: 25 in the experimental group and 24 in the control group. The program adaptation was conducted between April 2021 and November 2021 in Korea. The data were analyzed by ANCOVA and t-test to examine the effects using SPSS 26.0 program.

Results
After intervention of the program, environmental severity (F = 17.96, p < .001), response efficacy (F = 15.69, p < .001), and total environmental perception (F = 7.80, p = .008) were higher in the experimental group than in the control group. There were no significant differences in feasibility, accessibility, satisfaction, susceptibility, self-efficacy, barrier, personal environmental behavior, and community environmental behavior between the two groups.

Conclusion
The internet-based educational program can be the alternative for the face-to-face prenatal class to promote environmental health perceptions during pregnancy in the pandemic situations.
Education in Japan: A Comprehensive Analysis of Education Reforms and Practices, Yuto Kitamura, Toshiyuki Omomo and Masaaki Katsuno (2019)
Authors: Hosoda Chika 
Published: November 2022

Review of: Education in Japan: A Comprehensive Analysis of Education Reforms and Practices, Yuto Kitamura, Toshiyuki Omomo and Masaaki Katsuno (2019)
Singapore: Springer, 241 pp.,
ISBN 978-9-81132-630-1, e-book, £95.50
Two n × n G-classes of matrices having finite intersection
Authors: Golshan Setareh , Armandnejad Ali , Hall Frank J. 
Published: November 2022

Abstract
Let

M

n

{{\bf{M}}}_{n}

be the set of all

n
×
n

n\times n

real matrices. A nonsingular matrix

A
∈

M

n

A\in {{\bf{M}}}_{n}

is called a G-matrix if there exist nonsingular diagonal matrices

D

1

{D}_{1}

and

D

2

{D}_{2}

such that

A

−
T

=

D

1

A

D

2

{A}^{-T}={D}_{1}A{D}_{2}

. For fixed nonsingular diagonal matrices

D

1

{D}_{1}

and

D

2

{D}_{2}

, let

G

(

D

1

,

D

2

)

=

{

A
∈

M

n

:

A

−
T

=

D

1

A

D

2

}

,

{\mathbb{G}}\left({D}_{1},{D}_{2})=\left\{A\in {{\bf{M}}}_{n}:{A}^{-T}={D}_{1}A{D}_{2}\right\},

which is called a G-class. The purpose of this short article is to answer the following open question in the affirmative: do there exist two

n
×
n

n\times n

G-classes having finite intersection when

n
≥
3

n\ge 3

?
Brief Opioid Exposure Paradoxically Augments Primary Afferent Input to Spinal Excitatory Neurons via α2δ-1–Dependent Presynaptic NMDA Receptors
Authors: Chen Shao-Rui , Chen Hong , Jin Daozhong , Pan Hui-Lin 
Published: November 2022

Treatment with opioids not only inhibits nociceptive transmission but also elicits a rebound and persistent increase in primary afferent input to the spinal cord. Opioid-elicited long-term potentiation (LTP) from TRPV1-expressing primary afferents plays a major role in opioid-induced hyperalgesia and analgesic tolerance. Here, we determined whether opioid-elicited LTP involves vesicular glutamate transporter-2 (VGluT2) or vesicular GABA transporter (VGAT) neurons in the spinal dorsal horn of male and female mice and identified underlying signaling mechanisms. Spinal cord slice recordings revealed that µ-opioid receptor (MOR) stimulation with DAMGO initially inhibited dorsal root–evoked EPSCs in 87% VGluT2 neurons and subsequently induced LTP in 49% of these neurons. Repeated morphine treatment increased the prevalence of VGluT2 neurons displaying LTP with a short onset latency. In contrast, DAMGO inhibited EPSCs in 46% VGAT neurons but did not elicit LTP in any VGAT neurons even in morphine-treated mice. Spinal superficial laminae were densely innervated by MOR-containing nerve terminals and were occupied by mostly VGluT2 neurons and few VGAT neurons. Furthermore, conditionalGrin1knockout in dorsal root ganglion neurons diminished DAMGO-elicited LTP in lamina II neurons and attenuated hyperalgesia and analgesic tolerance induced by repeated treatment with morphine. In addition, DAMGO-elicited LTP in VGluT2 neurons was abolished by protein kinase C inhibition, gabapentin,Cacna2d1knockout, or disrupting the α2δ-1–NMDA receptor interaction with an α2δ-1 C terminus peptide. Thus, brief MOR stimulation distinctively potentiates nociceptive primary afferent input to excitatory dorsal horn neurons via α2δ-1–coupled presynaptic NMDA receptors, thereby causing hyperalgesia and reducing analgesic actions of opioids.SIGNIFICANCE STATEMENTOpioid drugs are potent analgesics for treating severe pain and are commonly used during general anesthesia. However, opioid use often induces pain hypersensitivity, rapid loss of analgesic efficacy, and dose escalation, which can cause dependence, addiction, and even overdose fatality. This study demonstrates for the first time that brief opioid exposure preferentially augments primary sensory input to genetically identified glutamatergic excitatory, but not GABAergic/glycinergic inhibitory, neurons in nociceptive dorsal horn circuits. This opioid-elicited synaptic plasticity is cell type specific and mediated by protein kinase C–dependent and α2δ-1–dependent activation of NMDA receptors at primary sensory nerve terminals. These findings elucidate how intraoperative use of opioids for preemptive analgesia paradoxically aggravates postoperative pain and increases opioid consumption and suggest new strategies to improve opioid analgesic efficacy.
Profile of The National Level 1 Physical Coach in 2022
Authors: Munawar Ahmad Al , Marpaung Hakim Irwandi , Azandi Fili , Abady Andi Nur 
Published: November 2022

This study aims to determine the profile of the national level 1 physical trainer in 2022 who has an important role in athlete achievement in the world of achievement sports. This research was conducted on training participants who have passed the National Accreditation Institute for Sports (Lankor) in collaboration with STOK Bina Guna. The method used is descriptive with survey data collection techniques.
From the data obtained, it can be concluded that the profile of the national level 1 physical trainer in 2022 when viewed from the age side is still very productive, in terms of the licenses they have are already qualified as trainers even though some trainers are considered to be very beginners, in terms of the length of time they train, they are considered physical trainers. The national level 1 has experience that can be applied when training, and in terms of educational background it is still dominated by sports graduates.
Elimination of E. faecalis and C. albicans Biofilm: A Comparison Between Single and Multiple File Systems in an Ex Vivo Study
Authors: Méndez-González Verónica , Casillas-Contreras Claudia , Vitales-Noyola Marlen , Alvarado-Hernández Diana Lorena , González-Amaro Ana María , Aragón-Piña Antonio , Pozos-Guillén Amaury 
Published: November 2022

To evaluate whether the WaveOne Gold and Reciproc single file instrumentation systems, are effective in reducing the microbial load of a mixed biofilm and the cleaning of apical third compared to the Twisted File Adaptive system (multiple-file system). Seventy mesial roots of the first and second molars were included and randomly divided into three experimental groups (n=20, n=10 controls). Biofilms were formed inside canals over 31 days. After instrumentation with the unique file systems, WaveOne Gold and Reciproc and the multiple file system Twisted File Adaptive, using 2.25% sodium hypochlorite as an irrigant in all cases, a count of colony forming units was performed using serial dilutions, cleaning of the apical third was evaluated using scanning electron microscopy. Comparisons amongst groups were made by using parametric and non-parametric statistics, according to a normal or non-normal data distribution, respectively. No significant differences in the reduction of the microbial load after employing a single-file system in comparison to the multiple-file system were found; in addition, the cleaning of the apical third was similar for the three different instrumentation systems. The single-file system is equal in effectiveness compared with the multiple-file system in reducing the microbial load.
Prácticas de ocio en universitarios modalidad distancia del programa Pedagogía Infantil de la Universidad del Tolima, Colombia
Authors: Tovar Torres Hernan Gilberto , Rodríguez Mendoza Gilberto , Gómez-Mazorra Mabel 
Published: November 2022

Objetivo: Describir las prácticas de ocio en universitarios modalidad distancia del programa académico de Pedagogía Infantil en Tolima, Colombia. Metodología: Estudio descriptivo transversal de tipo cuantitativo. Se analizan dos dimensiones del cuestionario ad hoc, “Características sociodemográficas y Prácticas de Ocio”. Resultados: los hallazgos evidencian, menos tiempo libre entre semana que los fines de semana, por alto porcentaje de ocupación laboral (60%), asimismo, los solteros y separados presentan mayor tiempo libre (50%). Predominan prácticas de ocio sedentario (ver televisión), las prácticas de fin de semana se diversifican en culturales, deportivas y recreativas. Al interior de la universidad, las prácticas se realizan con compañeros (50%), siendo las principales barreras: no tener tiempo (44%) y no tener dinero (22%). Los universitarios solicitan oferta de prácticas físico-deportivas (31%), culturales (23%) y lúdico-recreativas (17%). Conclusión: se sugiere organizar estrategias curriculares y extracurriculares que incorporen prácticas de ocio en estudiantes universitarios que fomenten el desarrollo humano.
SENSORIAMENTO REMOTO NO ESTUDO DA VEGETAÇÃO: PRINCÍPIOS FÍSICOS, SENSORES E MÉTODOS.
Authors: Guedes Jânio , Da Silva Sebastião Milton Pinheiro 
Published: November 2022

O termo Sensoriamento Remoto foi criado para designar o desenvolvimento dessa nova tecnologia de instrumentos capaz de obterem imagens da superfície terrestre a distâncias remotas. Avanços científicos e tecnológicos, conhecimentos referentes a equipamentos, plataformas e sensores, estão cada vez mais sofisticados, fornecendo enormes quantidades de dados sobre processos e fenômenos da superfície terrestre. O elo entre os objetos da superfície terrestre e os sensores remotos que os observam é a radiação eletromagnética (REM) e, desta forma, o entendimento sobre o funcionamento das interações entre a REM e os diferentes materiais (rochas, solos, vegetação, água, construções antrópicas, p.ex.) constitui-se em requisito chave para a interpretação dos dados coletados pelos diferentes sensores. Os sistemas imageadores fornecem como produto uma imagem da área observada, como por exemplo, os “scaners” e as câmaras fotográficas, enquanto que os sistemas não-imageadores, também denominados radiômetros ou espectroradiômetros, apresentam o resultado em forma de dígitos ou gráficos, sendo classificados como sensores passivos e ativos. No estudo dos recurss naturais, os índices de vegetação, constituim-se como algumas das inúmeras opõçes no estudo do mesmo, destacando pelos seus resultados satisfatórios nos últimos anos.
Palavras chaves: Corrida espacial, Imagens de satélite, índices de vegetação.
Evaluation of efficacy of ketamine nebulization on reduction of incidence and severity of postoperative sore throat due to tracheal intubation- A prospective randomized controlled study
Authors: Mehta Heli , Brahmbhatt Nimisha P , Patel Ankita , Bhamri Stuti 
Published: November 2022

Postoperative sore throat (POST) following endotracheal intubation during general anaesthesia (GA) is a common complication that leads to patient pain and is estimated to occur in approximately 21-65 percent of patients. The purpose of this study was to determine the efficacy of topical ketamine administration by nebulization in reducing the occurrence and severity of POST.After given written informed consent, a total of 134 patients with ASA I-II in the age range of 18-60 years, of either sex, undergoing surgery under GA were selected for this prospective, randomised, placebo-controlled, and double-blind trial. Patients were randomly assigned to one of two groups: group S received 5.0 ml saline nebulisation, while group K got ketamine 50 mg (1.0 ml) in combination with 4.0 ml saline nebulization for 15 minutes. GA was induced 10 minutes after nebulization was completed. After extubating, and at 2, 4, 6, 8, 12, and 24 hours post-operatively, POST monitoring was performed. POST was graded on a scale of 0 to 3.POST occurred in 44.03 percent of patients overall, with 41 patients in group S (61.19 percent) and 18 patients in group K (26.86 percent) experiencing POST throughout the study period. (0.001) (P = 0.001). At 2, 4, 6, 12, and 24 hours postoperatively, the use of ketamine nebulization significantly reduced POST (P 0.05). At 2 h (P=0.04) and 4 h (P = 0.002) postextubation, the severity of sore throat was also greater in the saline group than in the ketamine group.Preoperative nebulized ketamine is helpful at reducing the occurrence and severity of postoperative sore throat without causing any adverse effects.
A prospective study evaluating the effect of nebulised lidocaine on haemodynamic responses during nasotracheal intubation
Authors: Gaurav Shivani , Verma Reetu , Verma Hemlata , Verma Sateesh , Kuswaha Brij , Chaudhary Ajay Kumar , Singh Dinesh 
Published: November 2022

: Laryngoscopy and endotracheal intubation result in a significant increase in haemodynamic stress response which is well tolerated by healthy patients but in patients with significant coronary artery or cerebrovascular diseases, if it is not prevented adequately may lead to myocardial ischemia and cerebral haemorrhage.: This prospective comparative study was conducted between August 2019-July 2020 to study the effect of nebulised lidocaine on haemodynamic stress responses (primarily mean arterial blood pressure also heart rate, systolic blood pressure and diastolic blood pressure) during nasotracheal intubation. 94 patients who underwent head and neck surgery under general anaesthesia requiring nasotracheal intubation were randomised into two groups using a computational random number, Group A (control group): was nebulised with 5 ml of normal saline. Group B: was nebulised with 5ml of Lidocaine 4% solution. Heart rate(HR), systolic blood pressure(SBP), diastolic blood pressure(DBP), mean arterial blood pressure(MAP), and SpO2 were observed before and after nebulisation, just before intubation, immediately after intubation and at 3, 5 10 min after intubation.: On comparing SBP, DBP, MAP and heart rate immediately after intubation with pre-intubation values, there was a significant surge in both groups but an increase in the control group was more in comparison to the lidocaine group(p&#60;.05). Thereafter MAP, SBP, DBP and HR gradually decreased till the duration of study i.e. 10 minutes.: The administration of nebulised 4% Lidocaine inhalation before induction attenuates cardiovascular response (primarily in terms of MAP also SBP, DBP and HR) that occurs due to nasotracheal intubation.