bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Analysis of the Complete Chloroplast Genomes of Eight Ficus Species and Insights into the Phylogenetic Relationships of Ficus
Authors: Xia Xi , Peng Jingyu , Yang Lin , Zhao Xueli , Duan Anan , Wang Dawei 
Published: June 2022

The genus Ficus is an evergreen plant, the most numerous species in the family Moraceae, and is often used as a food and pharmacy source. The phylogenetic relationships of the genus Ficus have been debated for many years due to the overlapping phenotypic characters and morphological similarities between the genera. In this study, the eight Ficus species (Ficus altissima, Ficus auriculata, Ficus benjamina, Ficus curtipes, Ficus heteromorpha, Ficus lyrata, Ficus microcarpa, and Ficus virens) complete chloroplast (cp) genomes were successfully sequenced and phylogenetic analyses were made with other Ficus species. The result showed that the eight Ficus cp genomes ranged from 160,333 bp (F. heteromorpha) to 160,772 bp (F. curtipes), with a typical quadripartite structure. It was found that the eight Ficus cp genomes had similar genome structures, containing 127 unique genes. The cp genomes of the eight Ficus species contained 89–104 SSR loci, which were dominated by mono-nucleotides repeats. Moreover, we identified eight hypervariable regions (trnS-GCU_trnG-UCC, trnT-GGU_psbD, trnV-UAC_trnM-CAU, clpP_psbB, ndhF_trnL-UAG, trnL-UAG_ccsA, ndhD_psaC, and ycf1). Phylogenetic analyses have shown that the subgenus Ficus and subgenus Synoecia exhibit close affinities and based on the results, we prefer to merge the subgenus Synoecia into the subgenus Ficus. At the same time, new insights into the subgeneric classification of the Ficus macrophylla were provided. Overall, these results provide useful data for further studies on the molecular identification, phylogeny, species identification and population genetics of speciation in the Ficus genus.
DAYA HAMBAT INFUSED WATER JAHE PUTIH (Zingiber officinale var. amarum) TERHADAP PERTUMBUHAN BAKTERI STAPHYLOCOCCUS SP
Authors: Khusuma Ari 
Published: June 2022

The bacteria found in the sputum of patients with cough due to respiratory tract infections are Streptococcus bacteria and Staphylococcus aureus. Symptoms of cough can be treated with herbal remedies, one of which is drinking water from fruit juices, vegetables, herbs, and spices or what is later known as infused water. Plants that are believed to be able to inhibit bacterial growth are white ginger (Zingiber officinale var. amarum) because based on the results of phytochemical identification, ginger contains essential oil compounds and phenolic compounds that are antibacterial. This research aims to determine the inhibition of white ginger infused water on the growth of Staphylococcus sp. This research is a True Experiment with Completely Randomized Design (CRD), with white ginger infused water treatment with various concentrations. The results of the isolation and identification of sputum samples found Staphylococcus sp. The results of the sensitivity test of white ginger infused water as an antibacterial against Staphylococcus sp at all concentrations of 100%, 80%, 60%, and 40% were unable to inhibit the growth of Staphylococcus sp. The results showed that white ginger (Zingiber officinale var. amarum) infused water had no effect on inhibiting the growth of Staphylococcus sp.
CURRENT CHANGES LEGISLATION UNDER MARTIAL STATUS
Authors: Sizintsova Y. Y. 
Published: June 2022

The purpose of the study is to analyze the current labor, criminal and criminal procedure legislation, which was adopted in the martial law and events occurring in Ukraine.
Materials and Methods. The analysis of normative-legal acts adopted from
February 24, 2022, directly related to the rules and responsibilities of citizens of Ukraine, the work of public institutions in martial law. The provisions of labor, criminal and criminal procedure legislation of Ukraine are substantiated, which are extremely necessary during the investigation of criminal proceedings that are important for citizens of Ukraine, institutions of any form of ownership, working and continuing to implement state policy in hostilities.
Results and conclusions. The provisions of labor, criminal and criminal procedure legislation of Ukraine are substantiated, which are extremely necessary during the investigation of criminal proceedings that are important for citizens of Ukraine, institutions of any form of ownership, working and continuing to implement state policy in hostilities.
The procedure for conducting investigative actions by authorized persons, violation of current legislation and realization of the right to protection have been determined on the basis of study and analysis of legislative norms.
THE NOVEL MARKER OF REACTIVE HEPATITIS IN INJURED WITH GUNSHOT WOUNDS
Authors: Osodlo G. V. , Savichan K. V. 
Published: June 2022

Objective. The aim of the study was to improve the diagnosis of reactive hepatitis in injured with gunshot wounds.
Methods. A retrospective analysis of 373 medical histories of servicemen wounded during the war in eastern Ukraine in 2014-2020, 233 of whom were hospitalized at the National Military Medical Clinical Center (NMMCC) and military medical clinical centres of the North, South, Eastern regions of the Ministry of Defense of Ukraine for more than 14 days. All servicemen had laboratory examinations using unified methods of laboratory tests. The obtained data were processed using non-parametric statistical methods.
Results. The median baseline of ALT and, to a greater extent, AST (in the first period of traumatic illness) exceeds the upper limit of normal (40 IU / l). The highest values ​​of ALT were observed in the second period of traumatic illness on the 5th and 10th day of observation with a slight decrease in the next stage of the study. The concentration of AST increased significantly in the first period of traumatic illness, almost did not decrease in the second period, but approached normal values ​​≥14 days after injury. The strongest correlation between transaminases and albumin levels was found. A new calculated indicator in the form of the ratio of ALT concentration to albumin concentration (coefficient of reactive hepatitis of the injured, CRGI) is proposed. The development of post-traumatic reactive hepatitis was confirmed in all cases with the wounded with the value of CRGI ≥2.0.
Conclusions.
1. Based on a retrospective analysis of 373 case histories of wounded in different periods after a gunshot wound, a new calculated indicator is proposed - the coefficient of reactive hepatitis of the injured (CRGI) in the form of the ratio of ALT/albumin concentrations, the increase of which indicates hepatocellular damage of hepatocytes with simultaneous suppression of the protein-synthetic function of the liver on the background of catabolic reactions.
2. CRGI ≥2 indicates the development of reactive hepatitis, is most often observed in the second period of traumatic illness and tends to normalize in the background of effective treatment. In the wounded who died as a result of injuries, CRGI steadily increased and was significantly higher than in the wounded with the uncomplicated course, especially in the third period of traumatic illness - after 14 days or more (4.0 vs. 2.3, respectively), which indicates the possible use of the proposed indicator as a prognostic criterion for worsening the prognosis in the wounded.
CLINICAL CASE OF TUBEROUS SCLEROSIS AND DIAGNOSTIC POSSIBILITIES OF OPTICAL COHERENT TOMOGRAPHY AND ANGIOGRAPHY
Authors: Lutsenko N. S. , Rudycheva O. A. , Isakova O. A. , Kyrylova T. S. , Unguryan N. V. 
Published: June 2022

Objective(s). The aim is to determine the possibilities of optical coherence tomography (OCT), optical coherence tomography angiography (OCTA) of the eye in the diagnosis of tuberous sclerosis and to assess the dynamics of this rare pathological process.
Methods. The clinical case of a 19-year-old patient with tuberous sclerosis with involvement in the pathological process of the visual organ is presented. Ophthalmological examination and also examination of related specialists are carried out. Visual acuity was of the right eye was 1.0 and of the left eye was 1.0 with correction. One pathological focus was detected on the right eye during ophthalmoscopy. Two focuses were revealed on the left eye. OCT and OCTA of the eye were performed on the device Optovue RTVue 100 XR Avanti (Optovue Inc, USA). OCT was analyzed in different modes. Automatic and manual segmentation were used in OCTA analysis.
Results. OCT of the retina allowed to visualize homogeneous formations at the level of the inner layers of the neuroepithelium in the areas detected by ophthalmoscopy, and to exclude from the pathological process of the vitreous and choroid. The foci had clear boundaries and protruded into the vitreous. The retinal layers under the foci were dislocated and thinned, but the structure of all layers was clearly visible. Manual segmentation of OCTA showed a change in the location of large vessels of the superficial plexus and allowed to exclude the growth of abnormal vessels. Differential diagnosis was performed with retinoblastoma and inflammatory diseases, such as chorioretinitis. Confirmation of the type of phacomatosis in the patient was obtained by examination of other organs. The patient had 4 primary signs and 2 secondary signs of tuberous sclerosis.
Conclusion. The use of OCT and OCTA allowed to segment the retina and choroid, localize the pathological process and detect signs of retinal hamartoma. Identified primary and secondary signs of tuberous sclerosis in combination with ophthalmic manifestations (presence of retinal hamartomas) made it possible to establish the diagnosis.
Abnormal Uterine Bleeding in Early Reproductive Age. Outlook of Therapy with Dydrogesterone Duphaston
Authors: Иванишкина-Кудина О.Л. 
Published: June 2022

Одной из самых сложных проблем в гинекологии является терапия острых маточных кровотечений репродуктивного периода, выбор метода гемостаза и определение противорецидивной тактики лечения. Действия специалистов ограничены возрастными рамками, отсутствием четких клинических рекомендаций, наличием сопутствующих заболеваний, желанием избежать полипрагмазии. В статье представлены данные по клиническому обзору проблемы, собственные данные, касающиеся эффективности комплексной терапии маточных кровотечений пубертатного и раннего репродуктивного периода с применением препарата дидрогестерона Дюфастон, которые были проведены в период COVID-пандемии.
One of the most difficult problems in gynecology is the treatment of acute uterine bleeding of the reproductive period and the choice of a hemostasis method and the determination of anti-relapse treatment tactics. The actions of specialists are limited by age limits, the lack of clear clinical recommendations, the presence of concomitant diseases, and the desire to avoid polypharmacy. The article presents data on a clinical review of the problem, own data regarding the effectiveness of complex therapy for uterine bleeding in the puberty and early reproductive period with the use of dydrogesterone Duphaston, which were carried out during the COVID pandemic.
Organo-Functional Significance of the Small Salivary Glands and the Weber Gland in the Tonsillar Zone
Authors: Насыров В.А. , Насыров М.В. , Бакиева К.К. 
Published: June 2022

Цель. На основании патогистологических исследований ткани миндалин изучить типы локализации малых слюнных желез в тонзиллярной зоне и их функциональное значение.Материалы и методы. В исследование включены 226 пациентов от 3 до 70 лет, проведено патоморфологическое и гистологическое исследование удаленного материала миндаликовой ткани после тонзиллэктомии, абсцесс-тонзиллэктомии и после расширенных тонзиллэктомий. В исследование включались пациенты с гетерогенными нозологиями тонзиллярной области: с хроническим декомпенсированным тонзиллитом, неоплазмами и различными кистами миндалин и пр.Результаты. Результаты исследования показали, что наиболее заметными находками у всех обследованных, перенесших тонзиллэктомию, несмотря на отсутствие в анамнезе эпизодов ангин, в миндалинах являются признаки воспалительных изменений различной давности. При патогистологической верификации из всех миндалин слюнные железы присутствовали в 23% случаев. В качестве материала взяты 226 миндалин после различных способов тонзиллэктомии. В 5,7% случаев произведена операция абсцесс-тонзиллэктомии, и в 3 случаях из 4 обнаружены фрагменты малых слюнных желез.Заключение. Синтопия этих малых слюнных желез была обнаружена в верхней, средней и нижней частях тонзиллярного пространства. Это небольшое выборочное исследование исключает какое-либо определенное утверждение относительно связи малых слюнных желез и железы Вебера в генезе разного рода заболеваний.
Purpose. Based on pathohistological studies of tonsillar tissue, to study the types of localization of small salivary glands in the tonsillar zone, and their functional significance.Materials and methods. The study included 226 patients aged 3–70 years, pathomorphological and histological examination of the removed tonsillar tissue material after tonsillectomy, abscess-tonsillectomy and after extended tonsillectomies. The study criteria were patients with heterogeneous nosologies of the tonsillar region: with chronic decompensated tonsillitis, neoplasms and various tonsillar cysts, etc.Results. The results of the study showed that the most noticeable findings in all the examined patients who underwent tonsillectomy, despite the absence of angina episodes in the anamnesis, signs of inflammatory changes of various prescription were found in the tonsils. During pathohistological verification of all tonsils, salivary glands were present in 23% of cases. As a material, 226 tonsils were taken after various methods of tonsillectomy. An abscess-tonsillectomy operation was performed in 5.7% of cases, and fragments of small salivary glands were found in 3 out of 4 cases.Conclusion. The syntopia of these small salivary glands were found in the upper, middle and lower parts of the tonsillar space. This small sample study excludes any definite statement regarding the connection of the small salivary glands and the Weber gland in the genesis of various diseases.
Evaluation of Labors in COVID-19 Pandemic at Prof. Dr. R. D. Kandou Hospital Manado from January to August 2021
Authors: Dompas Virgyano L. , Tendean Hermie M. M. , Suparman Erna 
Published: June 2022

Abstract: Failure to prioritize maternal health during the COVID-19 pandemic will affect maternal mortality ratio (MMR). This study aimed to obtain the evaluation of labor during the COVID-19 pandemic. This was a descriptive and retrospective study with a cross-sectional design using the medical record data of Prof. Dr. R. D. Kandou Hospital in Manado. The results obtained 858 cases of labor. Based on maternal characteristics, most labors were carried out in the age group of 20-34 years (69.23%), household work (72.14%), senior high school education (51.52%), and parity of 1-4 times (60.72%). The highest percentage of labor was cesarean section (62.35%). Most of the antenatal care was carried out 4-6 times(34.62%) by obstetrician-gynecologists (40.09%). The most common labor complication was fetal distress (27.29%). Maternal deaths were 20 cases, most were caused by respiratory failure (50%). Perinatal mortality was 82 cases with the most common cause of death was intra uterine fetal death/IUFD (41.46%). The maternal mortality rate was 2442 cases per 100,000 live births meanwhile the perinatal mortality rate was 100.12 per 1000 live births. In conclusion, the most common labor was section caesarea. Respiratory failure was the most common cause of maternal mortality and IUFD was the most common cause of perinatal mortality.Keywords: labor, COVID-19, characteristics, maternal mortality, perinatal death Abstrak: Kegagalan dalam mengutamakan kesehatan ibu selama pandemi COVID-19 akan memengaruhi angka kematian ibu (AKI). Penelitian ini bertujuan untuk mengetahui evaluasi persalinan di masa pandemi COVID-19. Jenis penelitian ialah retrospektif deskriptif dengan desain potong lintang menggunakan data rekam medik Januari s/d Agustus 2021 di RSUP Prof Dr. R. D. Kandou Manado. Hasil penelitian mendapatkan 858 kasus persalinan. Berdasarkan karakteristik, persalinan paling banyak dilakukan pada kelompok usia 20-34 tahun (69,23%), pekerjaan ibu rumah tangga (IRT) (72,14%), pendidikan SLTA (51,52%), serta paritas 1-4 kali (60,72%). Jenis persalinan tertinggi yaitu persalinan seksio sesarea (62,35%). Pelayanan antenatal paling banyak dilakukan oleh dokter spesialis obstetri dan ginekologi (40,09%). Frekuensi pelayanan antenatal tertinggi yaitu sebanyak 4-6 kali (34,62%). Komplikasi persalinan tertinggi yaitu gawat janin (27,29%). Kematian maternal sebanyak 20 kasus dengan penyebab kematian tertinggi gagal napas (50%). Kematian perinatal sebanyak 82 kasus dengan penyebab kematian tertinggi IUFD (41,46%). Angka kematian maternal yaitu 2442 kasus per 100.000 kelahiran hidup. Angka kematian perinatal yaitu 100,12 per 1000 kelahiran hidup. Simpulan penelitian ini ialah jenis persalinan tertinggi seksio sesarea dengan gagal napas sebagai penyebab utama kematian maternal dan intrauterine fetal death (IUFD) sebagai penyebab utama kematian perinatal.Kata kunci: persalinan; kematian maternal; kematian perinatal; COVID-19
Change in surface properties of hemoglobin induced by heme reaction with O2 and CO
Authors: Maehira Ai , Che Dock-Chil , Matsumoto Takuya 
Published: June 2022

Abstract
The surface properties of hemoglobin bound to O2 (HbO2) or CO (HbCO) were investigated by ethanol precipitation, particle size analysis, and ζ potential measurements. We found that, compared with HbO2, HbCO is surrounded by more hydration water molecules, resulting in the greater physicochemical stability of HbCO in aqueous conditions. The intermolecular interactions of HbO2 and HbCO were studied by acquiring atomic force microscopy images under ambient air conditions. HbCO molecules easily aggregated on the hydrophilic mica substrate compared with HbO2 molecules during the dewetting process. We discuss these results in terms of a competing process between dispersion forces and adsorption on the hydrophilic mica substrate. The observed results suggest that the local structural differences between Fe–O2 and Fe–CO influence the surface structure of the protein, leading to the observed dissimilar physicochemical properties of HbO2 and HbCO.
Review for State-of-the-Art Health Monitoring Technologies on Airframe Fuel Pumps
Authors: Verhulst Tedja , Judt David , Lawson Craig , Chung Yongmann , Al-Tayawe Osama , Ward Geoff 
Published: June 2022

Aircraft maintenance is an essential cost borne by the airline. Improving maintenance practices for day-to-day operations can lead to significant financial savings. The benefits of effective maintenance are derived from the avoided costs caused by unexpected breakdowns and from maximising aircraft flight time transporting passengers. The fuel system is a crucial part of the entire aircraft as it ensures delivery of the fuel to the engine and a key component within this system are the fuel pumps. These airborne fuel pumps are classified between the pumps installed in the airframe fuel system and in the engine fuel system. Past works have investigated the performance characteristics of these pumps during flight, however there are no reviews related to the present Health Monitoring (HM) capabilities under flight conditions. HM refers to the field of diagnosing faults or predicting the remaining useful life (RUL) of the pump and the focus of this review is to highlight the HM technologies suitable for aircraft fuel pumps. This is done by first reviewing the technologies and concepts related to HM of fuel pumps. Second a literature review is carried out on pump and motor faults is carried out, drawing on examples from aerospace and other relevant industries. Section 6: Conclusion, discusses the HM technologies have been applied to aerospace fuel pumps and highlights the gaps in capabilities, based on the findings of the literature review carried out in Section 4: Common Faults and Section 5: HM Sensing Methods to suggest future developments in this field. It was found that there is a large scope for development for the HM airframe fuel pumps, based on reviewing the present state of the art. Furthermore, there are no clear strategies formulated by airframe manufacturers and equipment suppliers to test and implement existing HM solutions to operate under flight conditions. This highlights the need to develop HM in this field and a requirement for further research to allow this technology to be a part of routine aircraft
ДО ВИЗНАЧЕННЯ СТІЙКОСТІ РУХУ ТРИЛАНКОВОГО ПРИЧІПНОГО АВТОПОЇЗДА У ГАЛЬМІВНОМУ РЕЖИМІ
Authors: CАХНО Володимир , ПОЛЯКОВ Віктор , СТЕЛЬМАЩУК Валерій , ПOПЕЛИШ Денис 
Published: June 2022

У процесі екстреного гальмування ймовірність порушення стійкості автопоїзда зростає, особливо при нерівних гальмівних силах на колесах осей автопоїзда. В роботі розглядається стійкість автопоїзда в режимі гальмування. Зважаючи на те, що у випадку, що розглядається, сили взаємодії в тягово-зчіпних пристроях автобусів не впливають на перерозподіл навантажень по бортам ланок автопоїзда, досить складну систему – триланковий причіпний автопоїзд можна розглядати як три системи – три автобуси, що гальмують незалежно.
При дослідженні стійкості руху автопоїзда розглядають, як правило, плоскопаралельний рух його ланок. При цьому вважають, що нормальні реакції опорної поверхні на колеса правого і лівого борту однакові. За такої умови стійкість руху розглядають для плоскої моделі автопоїзда.
Розглянута динаміка гальмування триланкового пасажирського автопоїзда у складі трьох автобусів МАЗ-206. Показано, що врахування перерозподілу навантаження по осям і бортам автобуса за нерівності гальмівних сил по колесам його осей призводить до суттєвої зміни ГСР автобусного поїзда. Так, якщо при жорстких підвісках і шинах за швидкості 15 м/с автобусний поїзд за односторонньої нерівномірності гальмівних сил вже виходив за межі допустимої смуги руху, то з урахуванням деформацій підвіски і шин він за цієї швидкості залишався ще в межах допустимої смуги руху. Пояснюється це збільшенням кутів відведення коліс передніх осей у порівнянні із задніми, що забезпечило більший радіус повороту траєкторії автобуса, а відповідно і зменшенню відхилення траєкторії автобусів від прямолінійної.
Ключові слова: автобус, гальмування, нерівність гальмівних сил, стійкість, габаритна смуга руху
Analisis SWOT pada Pelaksanaan Kegiatan Pemilihan Pustakawan Berprestasi Terbaik Tingkat Nasional di Masa Pandemi COVID-19
Authors: Kinanti Kamilah , Herwati Novi 
Published: June 2022

Selection of the Best Outstanding Librarian at the National Level is one way to appreciate librarians who are highly dedicated to their duties. This event is carried out by the National Library of Indonesia through the Center for Librarian Development in a systematic and tiered manner, starting from the election at the provincial level to the national level. The COVID-19 pandemic brought a different color to the Selection of National Best Outstanding Librarian year 2020, which was held online for the first time. Through this study, it provides an overview of the differences in the offline and online selection process for Outstanding Librarians, as well as a SWOT strategy analysis for each mechanism. The studywas conducted with a descriptive qualitative approach. Data collection is done by document review and observation, analysis is done by SWOT analysis. The results obtained the portrait of the change in the mechanism for the Selection ofOutstanding Librarians, where the online selection process is fully carried out via the virtual meeting application and eliminating of visit activities. Meanwhile, in the SWOT analysis, the results obtained are the ST strategy on the offline mechanism and the WO strategy on the online mechanism.