bluuebunny/crossref_metadata_2025_split huggingface dataset:
Educação bilíngue para Surdos: um olhar para a leitura e a escrita a partir de uma RSL
Authors: Souza Eduarda Monteiro de , Valentini Carla Beatris , Pescador Cristina Maria 
Published: May 2022

Este estudo, de natureza qualitativa, consiste em uma pesquisa de cunho bibliográfico, a partir da Revisão Sistemática de Literatura (RSL). Tem por objetivo analisar como os estudos publicados no Brasil no período compreendido entre 2010 e o primeiro trimestre de 2022 discutem a aquisição da leitura e escrita pela criança surda. A análise busca suporte em um quadro teórico com foco em educação de surdos, língua de sinais e educação bilíngue e abrange um total de 47 artigos científicos publicados em periódicos nacionais e disponíveis nas bases de dados SCIELO e CAPES no período mencionado. O estudo se propõe a responder às perguntas “Como a educação bilíngue para surdos está sendo entendida no Brasil?” e “Qual o papel da Língua Brasileira de Sinais (Libras) no processo de alfabetização da criança surda?”. Foi possível identificar quatro concepções de educação bilíngue, além de diferentes composições para o corpo docente e diferentes possibilidades para a escola bilíngue e escola inclusiva. Percebe-se também que os estudos analisados apresentam um ponto em comum que é a importância atribuída à Libras e como isso se articula no processo de aquisição de uma segunda língua para os surdos. As autoras deste trabalho destacam a necessidade de que se discuta mais a educação para surdos e que isso seja mais difundido e estudado, não somente por pessoas surdas ou que trabalham com surdos, mas que envolva outros profissionais que contribuem e atuam na educação.
Diabetes mellitus y su asociación con el carcinoma oral de células escamosas: una revisión de la literatura
Authors: Vega García Marco Miguel , Martínez León Andrea Margarita , Bravo Calderón Diego Mauricio 
Published: May 2022

El carcinoma oral de células escamosas es un tumor maligno caracterizado por la proliferación incontrolable, excesiva e irreversible de células escamosas del epitelio bucal, representando la mayoría de todos los cánceres orales. Interesantemente, a pesar del avance en los procedimientos terapéuticos como radioterapia, quimioterapia y técnicas quirúrgicas, la tasa de supervivencia no ha mejorado en las últimas décadas. Por otro lado, la diabetes mellitus es una enfermedad crónica con presentaciones clínicas y trastornos metabólicos caracterizados por el aumento de los niveles de la glucosa en sangre. Diversos estudios plantean una posible relación entre estas dos entidades; evidenciando que una persona con diabetes y, además, mal controlada, puede tener diversas manifestaciones orales, como puede ser, el posible desarrollo de lesiones malignas orales. El objetivo del presente manuscrito es presentar y discutir la evidencia científica actualizada sobre la relación entre la diabetes mellitus y el carcinoma oral de células escamosas.
Understanding of Crucial Factors for Improving the Energy Density of Lithium-Sulfur Pouch Cells
Authors: Leonet Olatz , Doñoro Álvaro , Fernández-Barquín Ana , Kvasha Andriy , Urdampilleta Idoia , Blázquez J. Alberto 
Published: May 2022

Rechargeable lithium−sulfur (Li−S) batteries are the most promising next-generation energy storage system owing to their high energy density and low cost. Despite the increasing number of publications on the Li-S technology, the number of studies on real prototype cells is rather low. Furthermore, novel concepts developed using small lab cells cannot simply be transferred to high-energy cell prototypes due to the fundamental differences. The electrolyte and lithium anode excess used in small lab cells is known to have a huge impact on the cycle life, capacity, and rate capability of the Li-S system. This work analyses the performance of pouch cell prototypes demonstrating the potential and hurdles of the technology. The impact of electrolyte variations and the sulfur cathode loading are studied. The energy density of Li-S pouch cell is improved up to 436 Wh kg−1 by a combination of different approaches related to cell manufacturing, sulfur cathode optimization, and electrolyte amount adjustment.
Myocardial Injury Predicts Risk of Short-Term All-Cause Mortality in Patients With COVID-19: A Dose–Response Meta-Analysis
Authors: Li Yuehua , Pei Hanjun , Zhou Chenghui , Lou Ying 
Published: May 2022

ObjectivePredictive value of myocardial injury as defined by elevated cardiac tropnins (cTns) in patients with COVID-19 has not been fully investigated. We performed a meta-analysis to evaluate the dose–response relationship between myocardial injury and short-term all-cause mortality.MethodsPubmed, Embase, and the Cochrane Library database were searched for all the studies which evaluated the relationship between cTns and the risk of short-term all-cause mortality in patients with COVID-19.ResultsCompared with patients without myocardial injury, the group with elevated cTns was associated with increased short-term mortality (11 studies, 29,128 subjects, OR 3.17, 95% CI 2.19–4.59, P = 0.000, I2 = 92.4%, P for heterogeneity 0.00). For the dose–response analysis, the elevation of cTns 1 × 99th percentile upper reference limit (URL) was associated with increased short-term mortality (OR 1.99, 95% CI 1.53–2.58, P = 0.000). The pooled OR of short-term mortality for each 1 × URL increment of cTns was 1.25 (95% CI 1.22–1.28, P = 0.000).ConclusionWe found a positive dose–response relationship between myocardial injury and the risk of short-term all-cause mortality, and propose elevation of cTns &gt; 1 × 99th percentile URL was associated with the increased short-term risk of mortality.
Stereotactic Ablative Radiotherapy of Ventricular Tachycardia Using Tracking: Optimized Target Definition Workflow
Authors: Dvorak Pavel , Knybel Lukas , Dudas Denis , Benyskova Pavla , Cvek Jakub 
Published: May 2022

Background and PurposeStereotactic arrhythmia radioablation (STAR) has been suggested as a promising therapeutic alternative in cases of failed catheter ablation for recurrent ventricular tachycardias in patients with structural heart disease. Cyberknife® robotic radiosurgery system utilizing target tracking technology is one of the available STAR treatment platforms. Tracking using implantable cardioverter-defibrillator lead tip as target surrogate marker is affected by the deformation of marker–target geometry. A simple method to account for the deformation in the target definition process is proposed.MethodsRadiotherapy planning CT series include scans at expiration and inspiration breath hold, and three free-breathing scans. All secondary series are triple registered to the primary CT: 6D/spine + 3D translation/marker + 3D translation/target surrogate—a heterogeneous structure around the left main coronary artery. The 3D translation difference between the last two registrations reflects the deformation between the marker and the target (surrogate) for the respective respiratory phase. Maximum translation differences in each direction form an anisotropic geometry deformation margin (GDM) to expand the initial single-phase clinical target volume (CTV) to create an internal target volume (ITV) in the dynamic coordinates of the marker. Alternative GDM-based target volumes were created for seven recent STAR patients and compared to the original treated planning target volumes (PTVs) as well as to analogical volumes created using deformable image registration (DIR) by MIM® and Velocity® software. Intra- and inter-observer variabilities of the triple registration process were tested as components of the final ITV to PTV margin.ResultsA margin of 2 mm has been found to cover the image registration observer variability. GDM-based target volumes are larger and shifted toward the inspiration phase relative to the original clinical volumes based on a 3-mm isotropic margin without deformation consideration. GDM-based targets are similar (mean DICE similarity coefficient range 0.80–0.87) to their equivalents based on the DIR of the primary target volume delineated by dedicated software.ConclusionThe proposed GDM method is a simple way to account for marker–target deformation-related uncertainty for tracking with Cyberknife® and better control of the risk of target underdose. The principle applies to general radiotherapy as well.
B-Lines by Lung Ultrasound Can Predict Worsening Heart Failure in Acute Myocardial Infarction During Hospitalization and Short-Term Follow-Up
Authors: He Jiexin , Yi Shixin , Zhou Yingling , Hu Xiangming , Lun Ziheng , Dong Haojian , Zhang Ying 
Published: May 2022

BackgroundAcute myocardial infarction (AMI) with pulmonary edema shows a worse prognosis. Lung ultrasound (LUS) is a new tool for evaluating subclinical pulmonary congestion. It has been proved to predict prognosis in heart failure; however, whether it can be used as a short-term prognostic marker in AMI and provide incremental value to Killip classification is unknown.MethodsWe performed echocardiography and LUS by the 8-zone method in patients enrolled in Guangdong Provincial People's Hospital undergoing percutaneous coronary intervention for AMI from March to July 2021. The lung water detected by LUS was defined as B-lines, and the sum of the B-line number from 8 chest zones was calculated. Besides, the classification into LUS according to the pulmonary edema severity was as follows: normal (B-line numbers &lt;5), mild (B-line numbers ≥5 and &lt;15), moderate (B-line numbers ≥15 and &lt;30), and severe (B-line numbers ≥30). The NT-proBNP analysis was performed on the same day. All patients were followed up for 30 days after discharge. The adverse events were defined as all-cause death, worsening heart failure in hospitalization, or re-hospitalization for heart failure during the follow-up.ResultsSixty three patients were enrolled consecutively and followed up for 30 days. The number of B-lines at admission (median 7[3–15]) was correlated with NT-proBNP (r = 0.37, p = 0.003) and negatively correlated with ejection fraction (r = −0.43; p &lt; 0.001) separately. In the multivariate analysis, B-line number was an independent predictor of short-term outcomes in AMI patients (in-hospital, adjusted OR 1.13 [95% CI: 1.04–1.23], P = 0.006; 30-day follow-up, adjusted OR 1.09 [95% CI: 1.01–1.18], P = 0.020). For in-hospital results, the area under the receiver operating characteristic curves (AUCs) were 0.639 (P = 0.093), 0.837 (P &lt; 0.001), and 0.847 (P &lt; 0.001) for Killip, LUS and their combination, respectively. For the diagnosis of 30-day adverse events, the AUCs were 0.665 for the Killip classification (P = 0.061), 0.728 for LUS (P = 0.010), and 0.778 for their combination (P = 0.002).ConclusionB-lines by lung ultrasound can be an independent predictor of worsening heart failure in AMI during hospitalization and short-term follow-up and provides significant incremental prognostic value to Killip classification.
Seasonal Variation in Chemical Composition of Total Suspended Particles During the COVID-19 Pandemic in the Source Area of Urumqi River, Tianshan, China
Authors: Zheng Cunying , Li Zhongqin , Zhang Xin , Jiang Huimin , Zhou Xi 
Published: May 2022

The research of atmospheric aerosol in mountain glacier areas has attracted more and more people’s attention. For the first time, a field observation study of total suspended particles (TSPs) for four seasons from September 2019 to August 2020 was carried out at the Tianshan Glaciological Station in the source area of Urumqi River, East Tianshan Mountains, China. The TSPs presented typical seasonal characteristics of high in autumn and low in winter, with the annual average value of 181 ± 170 μg m−3. Concentrations of Ca2+, SO42−, NO3−, Cl−, NH4+ and K+, OC, EC were elevated in autumn. The influence of stationary source emissions was stronger than mobile sources, which was explained by the average ratio of NO3−/SO42− (0.31 ± 0.17). The concentration of secondary organic carbon (SOC) was higher in summer and autumn, especially in summer, indicating that secondary formation processes of organic aerosols were frequent in summer. Impact of fossil fuel combustion sources were evident over the Glaciers, corroborated by the diagnostic mass ratios of OC/EC (0–21.4, 3.38) and K+/EC (0–0.31, 0.08). The factor analysis illustrated that aerosols were mainly affected by rock salt, dust, coal combustion, and automobile exhaust. The local sources made significant contributions to TSPs in the source of Urumqi River by the results of Results of Hybrid Single Particle Lagrangian Integrated Trajectory (HYSPLIT) model and potential source contribution function (PSCF).
Modified Hydrological Regime on Irrigation and Water Supply in Lake Areas: A Case Study of the Yangtze River–Dongting Lake
Authors: Fang Juanjuan , Li Yitian , Wang Dong , Xie Shuai 
Published: May 2022

Lake systems are of fundamental significance for the ecological environment and social development. Driven by climatic changes and human activities, the hydrological situation of rivers and lakes has been altered considerably, and it has directly affected the reliability of irrigation and water supply in lake areas. In the case of the Yangtze River–Dongting Lake area, the quasi-equilibrium of their hydrological states and water balance have been affected by the operation of the Three Gorges Project that has led to irrigation and water supply problems across the lake area. Ever since, the available water supply in the Dongting Lake area has decreased by 31.5% and 47.7% during the months of September and October, and the overall water level in the lake area has dropped by 0.8–2.0 m. The proportion of domestic and agricultural irrigation water demands to available water supply in the Dongting Lake area is very small, and the decline of water level is the main reason for the lack of water supply in Dongting Lake area, Although the total amount of water in the lake area is still above the water supply threshold, an obvious decreasing trend has been observed in the fulfillment of the demand for both irrigation and water supply in urban and rural regions. Additionally, the fulfillment of secured water supply and irrigation requirements has respectively dropped from 95% to 78% before the operation of the Three Gorges Project to 82% and 46% after it. Meanwhile, the total water shortage increased from 57.683 to 143.607 million cubic meters. By advancing or postponing impoundment schedules, the impact of the Three Gorges Reservoir on irrigation and water supply in the lake area during September and October can be alleviated, and the water supply capacity can be respectively increased by approximately 1.3% and 1.4%. The highlights of this study include the quantification of the impacts of the operation of large-scale water conservancy projects at the level at which the requirements on irrigation and water supply in the lake area are satisfied, and the prediction of the trends for future evolvement. In addition, corresponding strategies that provide a technical reference for the comprehensive regulation and control over water resources and the security of water supply in the river basin are discussed.
Fasting Serum IGFBP-1 as a Marker of Insulin Resistance in Diverse School Age Groups
Authors: Bhangoo Amrit , Gupta Rishi , Shelov Steve P. , Carey Dennis E. , Accacha Siham , Fennoy Ilene , Altshuler Lisa , Lowell Barbara , Rapaport Robert , Rosenfeld Warren , Speiser Phyllis W. , Ten Svetlana , Rosenbaum Michael 
Published: May 2022

IntroductionThe known markers of insulin resistance in obese children are well studied. However, they require serial measurements and complicated calculations. The objective is to study IGFBP-1 and its relation with other known risk measures.Materials and MethodsThe study included 98 New York City school students of diverse ethnic/racial backgrounds (57 males and 41 females), 11–15 years of age. Subjects were enrolled in a cross-sectional study, and anthropometric measures were collected. They underwent fasting intravenous glucose tolerance tests (IVGTT), and glucose, insulin, lipids, IGFBP-1, adiponectin and inflammatory markers were collected.ResultsThe subjects were stratified into 3 groups based upon the BMI Z-score. Out of all the subjects, 65.3% were in the group with a BMI Z-score &lt;1 SDS, 16.3% subjects were in the group with a BMI Z-score of 1 to 2 SDS, and 18.4% of the subjects were in the group with a BMI Z-score of more than 2 SDS. The group with a BMI Z-score of more than 2 SDS had increased waist circumference (WC), body fat, increased fasting insulin, and triglycerides (TG). This group had decreased levels of adiponectin and HDL and low IGFBP-1 as compared to the group with BMI &lt;1 SDS. The group with a BMI Z-score of 1 to 2 SDS had a decreased level of IGFBP-1 as compared to the group with a BMI Z-score less than 1 SDS. IGFBP-1 inversely correlated with age, WC, BMI, body fat, TG, and insulin levels. IGFBP-1 positively correlated with adiponectin and HDL levels.ConclusionIGFBP-1 in children can identify the presence of insulin resistance in the group with BMI 1 to 2 SDS, even before the known markers of insulin resistance such as elevated triglycerides and even before decreased HDL and adiponectin levels are identified.
Obesity and Its Impact on Adverse In-Hospital Outcomes in Hospitalized Patients With COVID-19
Authors: Keller Karsten , Sagoschen Ingo , Schmitt Volker H. , Sivanathan Visvakanth , Espinola-Klein Christine , Lavie Carl J. , Münzel Thomas , Hobohm Lukas 
Published: May 2022

BackgroundAn increasing level of evidence suggests that obesity not only is a major risk factor for cardiovascular diseases (CVDs) but also has adverse outcomes during COVID-19 infection.MethodsWe used the German nationwide inpatient sample to analyze all hospitalized patients with confirmed COVID-19 diagnosis in Germany from January to December 2020 and stratified them for diagnosed obesity. Obesity was defined as body mass index ≥30 kg/m2 according to the WHO. The impact of obesity on in-hospital case fatality and adverse in-hospital events comprising major adverse cardiovascular and cerebrovascular events (MACCE), acute respiratory distress syndrome (ARDS), venous thromboembolism (VTE), and others was analyzed.ResultsWe analyzed data of 176,137 hospitalizations of patients with confirmed COVID-19 infection; among them, 9,383 (5.3%) had an additional obesity diagnosis. Although COVID-19 patients without obesity were older (72.0 [interquartile range (IQR) 56.0/82.0] vs. 66.0 [54.0/76.0] years, p &lt; 0.001), the CVD profile was less favorable in obese COVID-19 patients (Charlson comorbidity index 4.44 ± 3.01 vs. 4.08 ± 2.92, p &lt; 0.001). Obesity was independently associated with increased in-hospital case fatality (OR 1.203 [95% CI 1.131–1.279], p &lt; 0.001) and MACCE (OR 1.168 [95% CI 1.101–1.239], p &lt; 0.001), ARDS (OR 2.605 [95% CI 2.449–2.772], p &lt; 0.001), and VTE (OR 1.780 [95% CI 1.605–1.973], p &lt; 0.001) and also associated with increased necessity of treatment on intensive care unit (OR 2.201 [95% CI 2.097–2.310], p &lt; 0.001), mechanical ventilation (OR 2.277 [95% CI 2.140–2.422], p &lt; 0.001), and extracorporeal membrane oxygenation (OR 3.485 [95% CI 3.023–4.017], p &lt; 0.001).ConclusionsObesity independently affected case fatality, MACCE, ARDS development, VTE, and other adverse in-hospital events in patients with COVID-19 infection. Obesity should be taken into account regarding COVID-19 prevention strategies, risk stratification, and adequate healthcare planning. Maintaining a healthy weight is important not only to prevent cardiometabolic diseases but also for better individual outcomes during COVID-19 infection.
Rainwater Harvesting Systems That Reduce Water Consumption With Optimal Locations of Solar Concentration Power Plants
Authors: Murillo-Alvarado Pascual Eduardo , Cárdenas Gil Marco Antonio 
Published: May 2022

At present, the increase in population has caused an increase in the demand for electrical energy, which creates saturation in the national electrical system. In addition to this, the main source of energy for the generation of electricity is fossil fuels, which causes environmental pollution problems due to the increase in the concentration of greenhouse gases. To counteract the negative environmental impact, new energy sources that are friendlier to the environment have been sought, such as solar energy through power generation plants using solar concentrators. In this sense, this research proposes a mathematical optimization model to determine the feasibility of installing electric power generation plants through solar concentrators, to satisfy the energy demand in cities with the highest demand for electric power in the state of Michoacán. The proposed model considers the availability of water resources, the demand for energy, the costs involved for the installation of power generation plants, and the sizing of water collection systems to reduce the consumption of fresh water that is extracted from natural sources. It is a linear integer mixed programming model, where two scenarios are analyzed, considering variation in the operating time of the thermal storage system and the incorporation of the rainwater harvesting system to reduce freshwater consumption. The results show that 237,600 MW can be produced by installing three of the six power generation plants considered and considering a 19 h operation with thermal storage, generating a profit from the sales of the energy produced of 6,326,700 USD/year. Likewise, with the sizing of the rainwater harvesting system, it is possible to collect 1,678 m3 for the operation of the three determined power generation plants.
Analyzing the Spatial Distribution of LST and Its Relationship With Underlying Surfaces in Different Months by Classification and Intersection
Authors: Wei Xiao , Wang Xiao-Jun 
Published: May 2022

Urban heat islands (UHIs) have become one of the most critical issues around the world, especially in the context of rapid urbanization and global climate change. Extensive research has been conducted across disciplines on the factors related to land surface temperature (LST) and how to mitigate the UHI effect. However, there remain deficiencies in the exploration of LST changes across time and their relationship with underlying surfaces in different temperature ranges. In order to fill the gap, this study compared the LST of each month by using the quantile classification method taking the Landsat 8 images of Nanjing on May 18th, July 21st, and October 9th in 2017 as the subject and then calculated the differences between July and May as well as that between July and October by an intersection tool taking the LST classes of July as the baseline. Additionally, the spatial pattern of each temperature class and intersection area was analyzed with the help of several landscape metrics, and the land contribution index (LCI) was utilized to better quantify the thermal contribution of each underlying surface to the area. The results indicated that the difference between months mainly reflected in the medium temperature area, especially between July and October, in which landscape patterns illustrated a trend of fragmentation and decentralization. The proportions of underlying surfaces in different types of intersection revealed the distinction of their warming and cooling degrees over time, in which the warming degree of other rigid pavement was higher in the warming process from May to July, and the cooling degree of buildings was greater in the cooling process from July to October. The LCI of each underlying surface in the entire study area was different from that in each temperature class, indicating that underlying surfaces had distinguished thermal contributions in different temperature ranges. This study is expected to fill the gap in previous studies and provide a new perspective on the mitigation of UHI.