bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the Relationship between socioeconomic attributes and resilience capacity of Murrah buffalo-based livestock production system in changing climatic scenario
Authors: Singh Ruchi , Maiti Sanjit , Garai Sanchita , Bhakat Mukesh , Dixit A K , Aggarwal Anjali , Gour Anil Kumar , Kadian KS 
Published: June 2022

Abstract
The present study was conducted in farming community who reared specifically Murrah buffalo in their livestock production system for their livelihood. Total 320 Murrah buffalo farmers from 4 district of Trans-Gangetic Plain Region of India were identified and data collected through focused group discussion, PRA tools and face to face interview to measure the resilience capacity and their socioeconomic variables. Statistical tools such as ‘Principal component analysis’ for index development, cumulative square root methods for categorization of respondents and regression analysis were performed for exploring relationship. Result depicted that majority of the farmers have medium level of climate resilience index score i.e. 0.456. Moreover, it was found that farmer’s involvement in social institute such as, gram panchayat, agriculture and dairy co-operative society, self-help group, farmers’ association etc. were effect the resilience capacity of the respondents in changing climatic scenario. Whereas, farmers for seeking information on government subsidies/schemes rely more on village level worker, agriculture development officer, veterinary officer, bank personnel, co-operative official, krishi vigyan kendra scientists, progressive farmers and local money lenders as these provide social safety nets as they are able to provide on time information as sources of adaptation options regarding various climate resilient practices towards climate change. The need for better technology inclusion and access to more formal systems of finance is necessary to increase the overall resilience capacity of households. However, the perceived significance of different indicators of resilience capacity was different across different categories of farming system in different areas.
China's low-carbon economic growth: An empirical analysis based on the combination of parametric and nonparametric methods
Authors: Xiu Jing , Zang Xiaoqiang , Piao Zhenggang , Li Liang , Kim Kwansoo 
Published: June 2022

Abstract
As the world's most populous developing country and the world's largest carbon emitter, China has already completed its 2020 Intended National Determined Contribution set out in the Paris Agreement. It achieved this result by adopting a dual goal strategy of economic growth and reducing carbon emission intensity, that is, low-carbon growth. Based on both parametric and nonparametric methods, quantitative and qualitative conclusions about China's low-carbon growth are presented. It is found that since the beginning of this century, China has maintained an annual growth performance of 1% in low carbon Total Factor Productivity (TFP) and low carbon technological progress rate. The Eastern region has leading advantages in low-carbon TFP, low-carbon technology advancement, low-carbon efficiency, and low-carbon technology leadership. It has the potential to be the first to reach its CO2 turning point. The inefficiency ratio of labor and CO2 is higher at the national level and in the Eastern region, with the two accounting for about seven-tenths and eight to nine-tenths, respectively. The difference is that at the national level, the input-output inefficiency is similar, and the inefficiency in the Eastern region is more from the input side, about eight tenths. At the present stage, China is still lenient in the implementation of low-carbon environmental regulations. In the future, the adjustment of low-carbon policy should pay attention to regional heterogeneity, focus on reducing labor and CO2 inefficiency, and be more stringent in policy implementation.
Efficacy and safety of voriconazole in the treatment of invasive pulmonary aspergillosis in patients with liver failure: study protocol for a randomized controlled clinical trial
Authors: Yu Xue , Xu Lejia , Zheng Jiaxing , Lei Ziying , Pang Yihua , Li Xiaojie , Zhu Jianyun , Liu Jing 
Published: June 2022

Abstract
Background: Acute-on-chronic liver failure (ACLF) is a common clinical type of liver failure, and patients with acute-on-chronic liver failure are prone to fungal infections, especially the increasing incidence of invasive pulmonary aspergillosis(IPA). Voriconazole is recommended as the first-line antifungal agent in the treatment of invasive aspergillosis, however, no recommendation has been given for patients with severe liver cirrhosis (Child-Pugh C) and liver failure. This trial aims to examine the therapeutic effects and safety of voriconazole in the treatment of IPA in patients with liver failure.Methods: This study is a non-double-blind randomized controlled trial. The 96 eligible acute-on-chronic liver failure patients complicated with invasive pulmonary aspergillosis will be randomly assigned to receive either the optimized voriconazole regimen or the recommended voriconazole regimen for patients with mild to moderate liver cirrhosis (Child-Pugh A and B), at a 1:1 ratio, with an 8-week follow-up period. The antifungal efficacy of voriconazole will be the primary outcome measure. Plasma voriconazole concentration; the laboratory examination(CRP, PCT, ESR, etc.); chest CT; adverse events; and mortality at week 4 and 8 will be the secondary outcome measures.Discussion: This trial aims to demonstrate the efficacy and safety of voriconazole in the treatment of IPA in patients with liver failure, which is expected to provide a reference for scientific optimization of voriconazole regimens and a realistic basis for the standardized treatment of acute-on-chronic liver failure patients complicated with invasive pulmonary aspergillosis.Trial registration: The trial was registered with the Chinese Clinical Trial Registry, ChiCTR2100048259. Registered on 5 July 2021.
The first cellulose/bentonite doped vanadium from natural bentonite and wheat wastes for oxidation of sulfur compounds
Authors: Naeimi Atena , Ardakani Mehdi Hatefi 
Published: June 2022

Abstract
A novel nanocomposite based on extracted cellulose from wheat wastes and natural bentonite was fabricated. Cellulose and bentonite were attached covalently (Cell/Bent composite) and vanadium complex was immobilized on it to have Cell/Bent@V Complex nanocomposite. It was further evaluated by SEM, TEM, ICP, AFM, XRD, XPS, and FT-IR. Catalytic activity of Cell/Bent@V Complex nanocomposite was evaluated on the oxidation of sulfides and oxidative coupling of thiols. The excellent conversion and selectivity were obtained for oxidation of sulfides to corresponding sulfoxides as a sole product and oxidative coupling of thiol to corresponding disulfides. The SEM, XRD, and FT-IR of recycled and reused catalyst were shown the high stability and activity of Cell/Bent@V Complex nanocomposite.
Treatment with aripiprazole once-monthly injectable formulation is effective in improving symptoms and global functioning in schizophrenia with and without comorbid substance use – A post hoc analysis of the ReLiAM study
Authors: Margolese Howard , Boucher Matthieu , Therrien Francois , Clerzius Guerline 
Published: June 2022

Abstract
Background: ReLiAM, Real-Life Assessment of Abilify Maintena, was the first reported long-term prospective non-interventional study for patients with schizophrenia treated with aripiprazole once-monthly injectable formulation (AOM) under real-life conditions. ReLiAM’s primary aim was to evaluate the evolution of global functional status in patients treated with AOM for 12 months in Canada. Methods: The objective of this post hoc analysis of the ReLiAM study is to investigate the treatment effects of real-life use of AOM over a 1-year period in the subgroup of patients with reported substance use compared with patients without substance use. Results: The results of this post hoc analysis demonstrate that treatment with AOM for 12 months in patients with schizophrenia was comparably effective in improving global functioning in subgroups of patients with and without concomitant substance use. Conclusions: These results support the use of AOM for the treatment of schizophrenia in patients with or without concomitant substance use.Trial registration: NCT02131415 on ClinicalTrials.Gov
An Autonomous Frequency Control Mechanism for Multi-Area Microgrids Incorporating with Distributed Energy Resources
Authors: YILDIZ Süleyman , Gunduz Hasan , Yildirim Burak , Ozdemir Mahmut Temel 
Published: June 2022

Abstract
Due to the intermittent nature of distributed energy resources (DER) utilised in power grids, considerable frequency variations arise when the capacity of the load frequency control (LFC) system is inadequate to correct for electricity generation and consumption imbalances. This issue may significantly increase when the microgrid is operating in isolated mode. Meanwhile, hydrogen-fuel cells are gaining traction as distributed energy storage units, assisting in the transition to a low or zeroemissions while also providing for greater operational flexibility with maintaining frequency stability. Nevertheless, power grids constantly face various uncertainties. To mitigate these uncertainties, this study purposes a new dual-input interval type-2 fuzzy fractional order PI-PD (DIT2-FPI-FPD) cascade controller with recently developed Improved-Salp Swarm Algorithm (I-SSA) for LFC of multi-area microgrids incorporating with various DER. The simulations are performed with real-time sun/wind data and genuine random load changes. Robustness of the proposed controller has been verified by sensitive case studies, which are showing the proposed controller is optimal and highly efficient.
Study on the influence of keratinized mucosa on the evolution of non-surgical peri-implant treatment in implants with peri-implantitis
Authors: Fons-Badal Carla , Panadero Rubén Agustín , Labaig-Rueda Carlos , Solá-Ruiz Maria Fernanda , García-Selva Marina , Font Antonio Fons 
Published: June 2022

Abstract
The main objective of this study was to evaluate the response to treatment in implants with peri-implantitis depending on the presence or absence of keratinized mucosa. Materials and Methods: 100 implants with peri-implantitis were treated non-surgically at the Prosthodontics and Occlusion Teaching Unit of the University of Valencia. Records were registered at day zero (recession, bleeding on probing, suppuration, probing depth, bone loss and plaque index), at 1, 3 and 6 months. Results: In both groups a slight increase in recession and disappearance of suppuration took place, and no bone loss was observed during the 6 months. However, both probing depth, bleeding on probing and plaque index, after an initial reduction, increased again in the group without keratinized mucosa (KM). Conclusions: Implants with KM presented better results after non-surgical treatment as well as in their medium-term evolution, although it would be advisable to increase the number of samples in order to achieve greater scientific evidence and standardization in the treatment protocol. Clinical relevance: The role of keratinized mucosa in the development of peri-implantitis has been mentioned in many publications, but less has been emphasized regarding its influence on the success of the treatment of this pathology. The presence of keratinized mucosa has been found to play a determinant role in the evolution of non-surgical treatment of peri-implantitis. The amount of keratinized mucosa should be considered in the treatment of peri-implantitis, as well as when planning connective tissue grafts accompanying the decontamination of implants in the absence of keratinized mucosa.
Safety of online MR-based adaptive ultra-hypofractionated radiotherapy for prostate cancer in China: Preliminary analysis of data from a phase II trial
Authors: Lu Ning-Ning , Han Su-Jun , Tian Yuan , Qin Shi-Rui , Guan You-Yan , Wang Dong , Xiao Ze-Jun , Shou Jian-Zhong , Xiao Zhen-Dong , Song Yong-Wen , Xia Wen-Long , Yan Ling-Ling , Xing Nian-Zeng , Li Ye-Xiong 
Published: June 2022

Abstract
Background This study aimed to evaluate the feasibility and safety of online adapt-to-shape (ATS) workflow for prostate cancer patients on 1.5-T MR linac in China. Methods This prospective phase II study enrolled patients with localized or oligometastatic prostate cancer. Ultra-hypofractionated radiotherapy (UHF-RT) with dose of 36.25-40 Gy in five fractions was delivered every other day. After each fraction, feasibility and tolerability of the treatment were assessed. The primary endpoints were acute grade 2 or above genitourinary (GU) and gastrointestinal (GI) toxicities after up to 12 weeks follow-up. Results From March 2021 to November 2021, 26 patients were enrolled (23 with localized prostate cancer, 3 with oligometastatic prostate cancer). For all fractions, the online ATS plans met the dose criteria for both the target volume and normal tissues. The median on-couch time was 55 (34–95) minutes and 39 (24–50) minutes with T2WI 6-minute sequence and 2-minute sequence scans, respectively. For 98.4% fractions, treatment was well tolerated. Twenty-four patients completed treatment and were followed-up for at least 2 weeks. Grade 2 or above GU and GI toxicities occurred in 33.3% and 8.3% patients, respectively; two patients had RTOG grade 3 GU toxicity (hourly nocturia). IPSS remained unchanged during UHF-RT, increased from week 2 (mean, 9.1) to week 4 (mean, 12.4), and then gradually decreased at week 6. Patient-reported urinary and bowel scores were consistent with IPSS. Conclusions UHF-RT with ATS workflow is well tolerated by patients with localized and oligometastatic prostate cancer, with only moderate GU and mild GI toxicities. Trial Registration: NCT05183074, ChiCTR2000033382
Making visible the cost of informal caregivers’ time in Latin America: a case study for major cardiovascular, cancer and respiratory diseases in eight countries
Authors: Espinola Natalia , Pichon-Riviere Andrés , Casarini Agustín , Alcaraz Andrea , Bardach Ariel , Cairoli Federico Rodriguez , Augustovski Federico , Palacios Alfredo 
Published: June 2022

Abstract
Background: Informal care is a key element of health care and well-being for society; however it is scarcely visible and studied in economic evaluations of healthcare. This study aims to estimate the use time and cost of informal care associated with cardiovascular diseases, pneumonia and ten different cancers in eight Latin American countries (Argentina, Brazil, Chile, Colombia, Costa Rica, Ecuador, Mexico and Peru). Methods: The good proxy approach was used to estimate the monetary value of informal care. To estimate the use of time, a compilation of data from an exhaustive literature review and econometric estimation was carried out. This data was validated through a survey of professional caregivers and interviews with experts. The national household surveys databases were processed to obtain the average wage per hour of a proxy of informal caregiver. Estimates are expressed in 2020 US dollars. Results: The study estimates approximately 1,900 million hours of informal care annually and $ 4,300 million per year in average use time cost for these fifteen diseases and eight countries analyzed. Cardiovascular diseases accounted for an informal care burden that ranged from 374 to 555 hours per year, while cancers varied from 512 to 1,825 hours per year. The informal care cost on GDP varied from 0.26% (Mexico) to 1.38% (Brazil), with an average of 0.82% in the eight Latin American countries. The cost of informal care time represents between 16% and 44% of the total economic cost (direct medical and informal care cost) associated with health conditions. Conclusions: The study shows that there is a significant informal care economic burden in different chronic and acute diseases in Latin American countries. The study highlights the relevance of including the economic value of informal care in the economic evaluations of healthcare.
The rich meteorology of Jezero crater over the first 250 sols of Perseverance on Mars
Authors: Rodriguez-Manfredi Jose , Juarez Manuel de la Torre , Sanchez-Lavega Agustin , Hueso Ricardo , Martinez German , Lemmon Mark , Newman Claire , Munguira Asier , Hieta Maria , Tamppari Leslie , Polkko Jouni , Toledo Daniel , Sebastian Eduardo , Smith Michael , Jaakonaho Iina , Genzer Maria , de Vicente-Retortillo Alvaro , Viudez-Moreiras Daniel , Ramos Miguel , Saiz-Lopez Alfonso , Lepinette Alain , Wolff Michael , Sullivan Robert , Gómez-Elvira Javier , Apestigue Victor , Conrad Pamela , Río-Gaztelurrutia T. del , Murdoch Naomi , Arruego Ignacio , Banfield Donald , Boland Justin , Brown Adrian , Ceballos Joaquin , Dominguez-Pumar Manuel , Espejo Servando , Fairen Alberto , Ferrandiz Ricardo , Fischer Erik , Garcia-Villadangos Miriam , Gimenez Silvia , Gomez-Gomez Felipe , Guzewich Scott , Harri Ari-Matti , Jimenez Juan , Jimenez Vicente , Makinen Teemu , Marin-Jimenez Mercedes , Martin-Rubio Carolina , Martin-Soler Javier , Molina Antonio , Mora-Sotomayor Luis , Lopez Sara Navarro , Peinado Veronica , Perez-Grande Isabel , Pla-Garcia Jorge , Postigo Marina , Prieto-Ballesteros Olga , Rafkin Scot , Richardson Mark , Romeral Julio , Romero Catalina , Savijärvi Hannu , Schofield John , Torres Josefina , Urqui Roser , Zurita Sofia , team MEDA 
Published: June 2022

Abstract
Perseverance's Mars Environmental Dynamics Analyzer (MEDA) is collecting data at Jezero Crater, characterizing the physical processes in the lowest layer of the atmosphere as no previous instrument did before. Here we show that temperature measurements at four heights capture the response of the atmospheric surface layer to multiple phenomena. We observe the transition from a stable nighttime thermal inversion to a diurnal, highly turbulent convective regime, with large vertical thermal gradients, and where local surface properties (such as Thermal Inertia) play an essential role. Recording multiple daily optical depths yielded higher aerosol concentrations in the morning than in the afternoon. Measured wind patterns are mainly driven by local topography, with a small contribution from regional winds. Daily and seasonal variability of relative humidity shows a complex hydrologic cycle. These observations raise new puzzles in which changes in surface albedo and thermal inertia may play an influential role. On a larger scale, surface pressure shows typical signatures of gravity waves and baroclinic eddies in a part of the seasonal cycle characterized before as low wave activity. These observations, combined and simultaneous, show the rich Jezero’s meteorology, and unveil the diversity of processes driving change on today’s Martian surface.
Design and Research of Form Controlled Planar Scaling Mechanism based on 4D Printing Technology
Authors: Zhang Wencai , Ge Zhenghao , Li Duanling 
Published: June 2022

Abstract
Structural members and kinematic pairs made of rigid materials can be flexibly used in practical applications and obtain shape-changing mechanisms. However, it also leads to a relatively complex mechanical structure and overmuch kinematic pairs, which increases the difficulty of controlling the mechanism and thus limits its application. The emergence of 4D printing technology and smart materials provides new ideas for simplifying shape-changing mechanism structure and innovation. Although smart materials are already being used in many types of mechanisms, they are almost always unique cases. How to organically combine with a specific mechanism, innovate the type of mechanism, and systematically research from structural design to deformation control is still a blank area. Therefore, this paper designs a type of novel mechanism consisting of an angulated scissor unit and a form-controlled unit, the form-controlled planar scaling mechanism, which can achieve drivable self-adjustment of size ratio under predetermined thermal stimulation. The shape-changing mechanism is thus extended to a form-controlled mechanism. This mechanism's construction method and structural principles are analyzed, and the critical structural design parameters required for deformation control are derived. Based on the above research, the core form-controlled unit that controls the deformation of this type of mechanism is designed structurally and extended to deformation control research. Finally, two sets of prototype machines are manufactured and verified the feasibility of the construction method and deformation control scheme and the correctness of the theoretical analysis. This type of mechanism promotes the innovation of mechanism design methods. It shows many application prospects in satellite deployment structures and space probe walking systems.
A Psychometric Examination of Persian Self-Care Activities Screening Scale (SASS-14) during COVID-19
Authors: Rahmani Rasol , Rostamian Morteza ,   3.	Fatemeh Mohammadzadeh, Rahmani Mohamad Reza , moghadam Fatemeh yaghoobi 
Published: June 2022

Abstract

Introduction: Self-care is an important and valuable principle in today's society due to its emphasis on the active role of individuals in maintaining their health. This study aims to investigate the psychometric properties of the Persian version of the Self-Care Activities Screening Scale (SASS-14) during COVID-19.Methods: After obtaining the written permission, SASS-14 was translated into Persian from the original English version. A convenient sampling of 400 Iranian people from March to November 2021 completed the online Persian questionnaire through social media. The construct validity evaluated via Explanatory Factor Analyses (EFA) and confirmed using Confirmatory Factor Analysis (CFA). The convergent validity was evaluated using Spearman correlation coefficients between the SASS-14 and Satisfaction With Life Scale (SWLS) and 36-Item Short-Form Health Survey (SF-36). It’s reliability was assessed through internal consistency and test-retest intra-class correlation coefficient (ICC). Results: The results of the present study showed that the Persian version of the scale (SASS-14) has the desired content and construct validity for use in Iranian society as the original scale. All items of the questionnaire obtained CVR scores greater than 0.62 and only two items were revised for CVI value. The results of the CFA confirmed the structure of the four-factor model with 14 items, and the indices of model fit showed that the model was sufficiently consistent with the data. Moreover, Cronbach's alpha coefficient and ICC values indicate a desirable level of internal consistency and test-retest reliability.Conclusion: The results of the study showed that the Persian SASS-14 scale enjoys good reliability and validity. This scale is useful for assessing the self-care activities in Iranian people during COVID-19.
Spatial-ID: a cell typing method for spatially resolved transcriptomics via transfer learning and spatial embedding
Authors: Shen Rongbo , Liu Lin , Wu Zihan , Zhang Ying , Yuan Zhiyuan , Guo Junfu , Yang Fan , Zhang Chao , Chen Bichao , Liu Chao , Guo Jing , Fang Guozhen , Zhang Yong , Li Yuxiang , Xu Xun , Yao Jianhua 
Published: June 2022

Abstract
Spatially resolved transcriptomics (SRT) provides the opportunity to investigate the gene expression profiles and the spatial context of cells in naive state. Cell type annotation is a crucial task in the spatial transcriptome analysis of cell and tissue biology. In this study, we propose Spatial-ID, a supervision-based cell typing method, for high-throughput cell-level SRT datasets that integrates transfer learning and spatial embedding. Spatial-ID effectively incorporates the existing knowledge of reference scRNA-seq datasets and the spatial information of SRT datasets. A series of quantitative comparison experiments on public available SRT datasets demonstrate the superiority of Spatial-ID compared with other state-of-the-art methods. Besides, the application of Spatial-ID on a SRT dataset with 3D spatial dimension measured by Stereo-seq shows its advancement on the large field tissues with subcellular spatial resolution.