bluuebunny/crossref_metadata_2025_split huggingface dataset:
Życie i śmierć męczenników przykładem wierności Bogu
Authors: Mazurowski Wiesław 
Published: July 2022

L'articolo tratta del martirio dei preti di Pelplin, di cioe le vittime delta seconda guerra mondiale, morti in nome della fedelta a Dio ed alla loro vocazione. Tutti che hanno subito la morte dalle mani dei nazisti per causa del loro odio verso la fede, hanno conservato la fede ed hanno dato agli altri la testimonianza delta fedelta a Dio.Le varie forme delta fedelta a Dio e alla loro vocazione si puo intravedere da tutti i candidati all'onore di martirio. Dagli uni dominava un ministero sacramentale, dagli altri un lavoro intellettuale, ancora dagli altri una preoccupazione per i poveri e bisognosi. ,,Vi sono diversita di carismi, ma uno solo e lo Spirito; vi sono diversita di ministeri, ma uno solo e il Signore; vi sono diversita di operazioni, ma uno solo e Dio, che opera tutto in tutti" (1 Corinzi 12,4-6).Si presenta la fedelta a Dio ed alla Nocazione sacerdotale: coll'assistenza per i poveri sull'esempio di vita e martirio di Rev. Antoni Henryk Szuman ( 1882-1939); coll'edilizia degli oggetti sacrali di Rev. Konstantyn Krefft ( 1867 -1940); col paziente subire di picchiate ed umiliazioni di Rev. Paweł Prabucki (1893-1942). Pure anche un lavoro intellettuale e una forma di fedelta a Dio. Ce ne hanno dato un esempio il Rev. Józef Roskwitalski (1893-1939) e Rev. Piotr Sosnowski (1899-1939). La difesa della castita e intoccabilita della natura umana davanti al martirio e stata una forma di fedelta presentata da Rev. Reginald Krzyżanowski (1894-1939) e Rev. Jan Lesiński (1908-1940). Rev. Bernard Łosiński (1865-1940) ha dato un esempio di un uomo umile, particolarmente davanti alla morte. Rev. Jan Hamerski (1880-1939) ha sperimentato una particolare forza di proclamazione della parola di Dio. Rev. Cyryl Karczyński (1884-1940) fu un eccezionale propagatore della cultura popolare polacca. Infine Rev. Franciszek Nogalski (1911-1939) ha dato la sua vita per gli altri, e Rev. Stefan Radtke (1890-1940) s'e dimostrato veritiero dichiarando davanti degli oppressori di essere un sacerdote.Dei martiri presentati sono come una risposta ai dubbi dell'uomo contemporaneo che si chiede sulla possibilita e lo stato di una familianta dell'uomo con Dio. G li esempi di vita dei martiri che umanamente parlando si sono trovati in una situazione senza uscita, sono un ammonimento su come non abbattersi davanti al male ed alla violenza trionfanti.
Sługa Jahwe (Iz 53,10-11a) i problem zmartwychwstania
Authors: Lemański Janusz 
Published: July 2022

Il testo di Is 52,13-53,12 presenta un vasto panorama dei probierni di natura esegetica. Questi, oltre i termini stessi e la loro sintassi, riguardano soprattutto l'identita del Servo interpretato sia in maniera collettiva sia quella individuale. Anche ił messaggio della pericope riguardo alla risurrezione possa essere capito sia metaforicamente sia in modo reale. Nella presente analisi viene scelta l'interpretazione colettiva del Servo. Non si esclude peró della possibilita di capire la persona del Servo in maniera individuale e la sua risurrezione doppo la marte come un primo tentativo di decrivere una realta post mortem. La ragione per questo, oltre alcuni elementi esegetici tratti dal testo masoretico, si trova anche nel postesilico sviluppo della idea di sostituzione: un giusto individuo per tanti peccatorii.
Popaschalne świadectwo Parakleta o sądzie Boga nad „światem” w ujęciu J 16,8-11
Authors: Kot Piotr 
Published: July 2022

Holy Spirit plays an important role in the theology of the fourth Evangelist. During the Last Super, and therefore right before his death, Jesus from Nazareth not only foretold the coming of the Holy Spirit, but also designated the nature of his mission. The Paraclete, as Jesus calls him, will “testify about” Jesus (John 15:26) and “will demonstrate to the world what sin, righteousness and judgment are about” (John 16:8). Many scholars, while interpreting these words, point to the juridical function of the Paraclete. Accordingly, the Paraclete would pass right judgment on the world in view of the sin of unbelief. However, a detailed exegetical analysis, taking into account the various narrative techniques employed by the author of the fourth Gospel, among them the technique of misunderstanding, allows for a different interpretation of Jesus’ words. Accusations against Jesus are very frequent in the fourth Gospel. The “world” calls him a “sinner” (8:46) and “one who blasphemes” (10:36). In the context of such charges, the passing of judgment on Jesus, as well as his crucifixion and death, were understood as a revelation of God’s justice in regard to Jesus. The Paraclete’s mission will consist in revealing to the “world” and to the disciples the meaning of these events in a reversed perspective. John describes his task by the use of the technique of irony. The Paraclete will reveal as true that Jesus indeed accepted death as a “sinner”, but in the sense of expiatory sacrifice antitype. For that reason, the justice of God has been realized not “in regard” to Jesus, but “in Jesus.” As a result, the “world’s” judgment on Jesus has, in fact, initiated God’s judgment on the “world” and its ruler. The Paraclete is to give a testimony about the victory of life over death in Jesus Christ, and thus to lead the “world” to faith, and the disciples to the fullness of faith.
Shortest paths in a diagraph with an underestimated arc weight
Authors: Ciupala L. , Deaconu A. , Majercsik L. 
Published: July 2022

There are many real-world problems that can be modeled and solved as shortest path problems. Among them, single-pair shortest path problems appear most frequently. Sometimes the weighted digraph, in which the shortest path problem is stated, suffers a minor data change (for instance, an arc weight might increase by a given amount a) due to the changes occurring in the corresponding real-life problem. In this case, one needs to solve the shortest path problem in the modified digraph. If shortest paths are already determined in the initial digraph, these can be used as a starting point when determining shortest paths in the modified digraph or a known shortest path algorithm can be applied, from scratch, in the modified digraph. We will describe an algorithm that determines the shortest paths from a given source
node s in the new weighted digraph starting from the already known shortest paths in the original weighted digraph.
Analysis of the dynamics of the nomenclature of medicines in the government program «Available medicines»
Authors: Костюк І. А. , Пелих Ю. В. 
Published: July 2022

The availability of medicines the public is a problem with the most acute health care systems. Not only the issue of physical availability of medicines, their availability in pharmacies, but also the economic assistance of the population to purchase drugs is relevant. To overcome these problems, the Government has recognized the introduction of a reimbursement process in the pharmaceutical sector. The content of improving the quality and life expectancy of the population, with increasing physical and economic accessibility of drugs for the treatment of the most socially significant diseases, April 1, 2017 the Government introduced a reimbursement program «Available medicines». In the beginning there were spreads with cardiovascular disease, type II diabetes and bronchial asthma. From October 1, 2021, the program includes drugs for the treatment of diabetes mellitus, mental and behavioral disorders, epilepsy.
The aim of the work is to study the dynamics of the range of drugs included in the government programs «Available medicines» for 2017–2022.
The content analysis of 13 issues of Registers of medicines subject to reimbursement shows the updating and growth of the number of international non-proprietary names and in accordance with the trade names of drugs for the treatment of nosologies, which countries have recognized as the best. The nomenclature of medicines has been updated twice with international non-proprietary names and in almost 3 varieties – by trade names compared to the first issue, which is associated with both the expansion of names for the treatment of the disease, which were in programs since 2017 and the emergence of new nosology from 2021. On average, the share of drugs of domestic pharmaceutical companies is only 60%, which opens a significant prospect of import substitution, reduces drug prices under the government program «Available medicines» and, for example, increase the physical and economic availability of drugs.
The conducted studies allow us to conclude that there is a need to improve the assortment policy of the government program «Available medicines» using the population of Ukraine available drugs in accordance with the needs of the population and the standards for the treatment socially significant diseases.
Results of clinical and economic analysis of pharmacotherapy of patients epilepts
Authors: Олєйнікова Н. В. , Корж Ю. В. , Сурікова І. О. , Афанасенко О. В. 
Published: July 2022

Epilepsy is one of the most common serious diseases of the central nervous system in the world. The effective system of pharmaceutical care for epileptic patients requires the involvement of appreciable budgetary financial resources. In order to determine the actual state of pharmaceutical care to the population, clinical and economic studies are used, the results of which allow to optimize the cost of pharmacotherapy and ensure the implementation of the constitutional rights of Ukrainian citizens to available medical and pharmaceutical care.
The aim of the study was to conduct a clinical and economic analysis of pharmacotherapy of epilepsy.
The object of the study was the data of 118 medical records of patients diagnosed with epilepsy, who were treating at specialized healthcare facilities. Evaluation of the degree of pharmacotherapy rationality in epileptic patients was taken using frequency, VEN, ABC analysis.
The results of the investigation of patients’ medical records showed that 87 trade names of medications (76 international non-proprietary names of medications) were prescribed for epileptic patients. The total number of prescriptions is 918. The average number of prescriptions per patient is 7, which indicates polypragmasy. It was found that the leader in the number of appointments were carbamazepine – 11.11% of the total number of prescriptions and valproic acid – 3.49%. It is proved that in the structure of prescriptions for epileptic patients the part of medication with index V was 7.89%, which indicates a low degree of prescriptions compliance with healthcare standards. According to the results of the integrated ABC and VEN analysis, it was proved that among the groups A/V, A/E, A/N, the group A/V has the largest amount of expenditures – 36.38% of total cost. In general, group N accounts for 41.97% of total costs, which may indicate the irrational use of drugs in the provision of pharmaceutical care to epileptic patients.
The results of clinical and economic analysis of medical records of epileptic patients allowed to identify features in the organization of pharmaceutical care, as well as to substantiate the main directions of improving pharmacotherapy of epileptic patients with limited budget funding for healthcare.
Study of structural-mechanical properties for choosing the basis of pharmaceutical composition in ointment form
Authors: Луцька А. В. , Дроздова А. О. 
Published: July 2022

Rational treatment of wounds is a pressing problem of our time, especially during hostilities. Practice has shown that currently there is no universal method of local wound healing. Therefore, a differentiated approach to the development of drugs for the local treatment of the wound process is needed. Among the dosage forms for topical use, soft drugs are a convenient dosage form for topical use. Thanks to the excipients which are a part of soft medicines, it is possible to regulate release of active pharmaceutical ingredients that, in turn, provides medical action of drug. The technology of drug preparation, which includes the substantiation of the temperature regime of drug production, the study of their physico-chemical and structural-mechanical properties affects the therapeutic efficacy of the drug.
The aim of the work was to study the structural and mechanical properties of model samples for choosing the basis of the pharmaceutical composition in the form of an ointment.
The object of the study were model samples of bases made on the basis of oil/water emulsion and water/oil. Measurements of rheological parameters of ointment bases and their homogeneity were performed according to the methods of the State Pharmacopoeia of Ukraine (2.2.10 and SPU 1 in Annex I).
Studies of thermal stability and colloidal stability were performed according to DSTU 4765: 2007. Cosmetic creams. General technical conditions. [Effective from 2009-01-01]. Rheological studies of model samples of ointment bases immediately after their manufacture and their physicochemical properties (homogeneity, thermal stability and colloidal stability) both after fabrication and during 6 months of storage at room temperature. It is proved that all samples have elastic-plastic-viscous properties, thixotropy and ability to lubricate well, homogeneity and thermal and colloidal stability.
The study of the structural and mechanical properties of model bases has shown that these samples of bases can be used as carriers of drugs in the development of soft drugs.
The prospect of this study is to study the osmotic properties of model samples in order to choose the basis that the medical and biological requirements will meet a certain phase of the wound process.
Research of the assortment and information support of medical products and cosmetics
Authors: Городецька І. Я. , Левицька О. Р. , Чухрай І. Л. 
Published: July 2022

An urgent problem of the contemporary domestic pharmaceutical market is the availability of a large number of products and goods that are not registered as medicines in the prescribed manner, but declare in different ways the medicinal properties and uses for therapeutic purposes. Without unified and comprehensible information resources on such products, this function is partially performed by the site Compendium.onLine.
The aim of the research was to consider of the assortment and accompanying information of medical products and cosmetics.
The object of our study was the data provided by the Internet resource Compendium.onLine. The subgroup «Liquids» from group 13 «Other products for treatment» of the section «Medical devices» and group 06 «Cosmetics for health» from the section «Cosmetics» were selected for the analysis, as their assortment was more typical for pharmacies.
147 items were presented in the subgroup «Liquids», which were offered by 51 manufacturers, one third of which were native companies. The predominant form of release was nasal spray – 42.2%, solutions (including for inhalation, for the oral cavity, ophthalmology, ear hygiene, for nails) represented 12.9% of the range items, eye drops – 8.2%, and throat spray – 4.8%. The subgroup «Cosmetics for Health» contained 634 products, which were produced by 163 manufacturers, two thirds of which were native firms. The predominant forms of release were cream (20.3%), gel (13.2%) and balm (11.5%). It was found that the analysed subgroups included some tools, the release forms of which did not correspond to the names of these subgroups.
94.3% of the range of health cosmetics contains recommendations for medical use. At the same time, 26.0% of them were diagnosed according to the International Classification of Diseases. Health cosmetics offered by drug manufacturers in 100% of cases have recommendations for their medical use. As cosmetics are not medicines, it is prohibited by law to declare their medicinal properties.
The study made it possible to characterize the structure of the range and accompanying information of two subgroups of medical products and cosmetics, the nomenclature of which is more typical of pharmacies. The problems inherent in the circulation of these groups of pharmaceutical products were identified and ways to solve them were suggested.
Modern approaches to studying the antimicrobial and antifungal activities of new 1,2,4-triazole derivatives
Authors: Оглобліна М. В. , Бушуєва І. В. , Парченко В. В. 
Published: July 2022

1,2,4-Triazole and its derivatives are a promising class of organic compounds. For a long time, they remain in the spotlight due to a number of unique properties: high ability to chemical transformations, the presence of various types of biological activity and, of course, low toxicity. Also, a number of 1,2,4-triazole derivatives are currently well studied and implemented in various spheres of human life as effective drugs, various plant protection products (growth stimulants, fungicides, herbicides), anti-corrosion materials, plasticizers, etc.
The aim of the work was to analyze and systematize new data on antimicrobial and antifungal activity of 1,2,4-triazole derivatives and to select a promising area of ​​research based on the accumulation of a large amount of information on the properties of new 1,2,4-triazole derivatives.
The analysis of modern sources of information in recent years argues and proves the prospects for finding new biologically active compounds in a number of 1,2,4-triazole derivatives. The information obtained clearly indicates the possibility of using 1,2,4-triazoles, which contain a Sulfur atom, as objects of study.
1,2,4-Triazole is one of the most well-known classes of biologically active compounds, which has a wide range of biological action. Derivatives of 1,2,4-triazole are characterized by the presence of antibacterial, antifungal, hypoglycemic, antihypertensive, analgesic, anti-inflammatory, antitumor, antiviral activities. The trend of creating new effective drugs based on 1,2,4-triazole derivatives is growing.
Some of the drugs are 1,2,4-triazole derivatives: ribavirin (an antiviral agent), risatriptan (a selective 5HT1 serotonin receptor agonist), alprazolam (an anxiolytic agent), fluconazole, and itraconazole (antifungal drugs). Derivatives of this compound have proven themselves well in veterinary medicine. Drugs such as Avesstim, Trifuzol, Trifuzol-neo are immunostimulants and in various dosage forms (1%, 2% solutions, suppositories) are used in veterinary farms, in the private livestock sector and for pets.
These facts are the best example for understanding the prospects of finding new molecules among 1,2,4-triazole derivatives.
Primary Actinomycosis of the Foot in a 37-year-old female Patient: A Case Study and Review of the Literature.
Authors: Xhaferi Nusret , Gavrilovski Antonio , Jakimova Marija , Ukaj Fatime , Dyla Dea , Ukaj Skender 
Published: July 2022

Abstract:
A parasitic disease called actinomycosis occurs when bacteria spread through body tissues, causing abscesses, inflammation, and pain. It affects the skin or deeper parts of the body and can sometimes affect the blood.[1] The symptoms of actinomycosis may mimic those of other diseases or even neoplasms. Remission and exacerbation of symptoms occurring in parallel sequence with the initiation and cessation of therapy is a phenomenon that should increase suspicion of actinomycosis in any of its manifestations. [2]
Microbiology, histopathology, and MRI revealed the presence of an unusual infectious agent, Actinomyces spp., which is also known as Madura foot [3] This implies a serious difficulty in getting a bactericidal concentration of the effective drug into areas of active infection and seriously questions the possibility of restoring the involved tissues [4, 8]
The diagnosis was confirmed by isolation of the organisms by anaerobic culture giving typical molar tooth colonies. Final confirmation was done by histopathological examination.
Case report; The patient's condition dates back 5 years before the operative treatment when for the first time the patient reported that she was stabbed with a foreign body in the area of ​​the left foot.
The patient was treated at home and in the beginning, did not go to the doctor. She occasionally complained of pain and swelling but the pain was not distressing, with no fever and no swelling of the foot…
Functional Outcome of Arthroscopic Meniscal Root Repair.
Authors: Antao Nicholas , Desouza Clevio 
Published: July 2022

Objectives: The aim of the study was to assess the functional outcome of the knee in patients before and after meniscal root repair.
Material and Methods: This study was a prospective study done on 52 patients with Meniscal Root tear treated by arthroscopic repair. The follow-up period was 6 weeks, 3 months, and 6 months. Functional outcome was assessed using the VAS and Lysholm Knee Score.
Results: The VAS pre-operative was 7.46, the VAS post-operative at 6 weeks was 4.23, the VAS post-operative at 3 months was 3.12 the VAS post-operative at 6 months was 1.19. As compared to preoperative scores at the end of 6 months the difference was statistically significant with a p-value < 0.001. Following surgery there was an excellent outcome in most of the cases with respect to the range of motion, overall, the improvement in the range of motion was statistically significant with a p-value < 0.001. On the evaluation of the Lysholm Knee Score, there was a significant difference between the pre-operative and post-operative scores at each follow-up. The pre-op was 68.52, the Lysholm Knee Score post-op - 6 weeks was 81.72, the Lysholm Knee Score post-op - 3 months was 85.72, and the Lysholm Knee Score post-op - 6 months was 92.23. As compared to preop scores at the end of 6 months the difference was statistically significant with a p-value < 0.001.
Conclusion: In the present study we found that sports-related injuries were commoner, seen more in males and in young. Following meniscus repair, it is possible to get a good range of motion back post-operatively. A fair number of cases get back their knee function if appropriate post-operative physiotherapy rehabilitation protocol is followed.
Success Rate and Complications Associated with the Surgical Treatment of Cervical Spondylosis Myelopathy in Albania.
Authors: Halili Nehat , Xhumari Artur 
Published: July 2022

Background: Patients suffering from cervical spondylotic myelopathy (SCM) and that do not respond to conservative treatment could benefit from anterior cervical spine surgery. However, surgical intervention is associated with increased risk of complications and therefore the decision to operate should be weighed against benefits. The purpose of this study was to describe the effectiveness and the rate of complications of anterior cervical spine surgery among CSM who do not respond to conservative treatment in Albania.
Material and Methods: A total of 100 CSM patients who did not respond to conservative treatment and who showed up at our Service during 2014-2019 were subjected to anterior cervical spine surgery to resolve the CSM related signs and symptoms. The success rate as well as short-term and long-term complication of surgery were evaluated and reported.
Results: The mean age of CSM patients (59% males) in the study was 51.5 years. One surgical procedure was employed in 90% of CSM patients whereas two procedures were necessary in the remaining 10%. The overall success rate of anterior cervical spine surgery was 70% (excellent in 40% of CSM patients and good in 30% of patients) whereas in 30% of CSM patients’ surgery did not bring any benefit or there were no changes compared to before the surgery. The overall rate of complications was 16%; no patients died following surgery. Specific complications were rare and varying from 1% of patients (Brown-Sequard syndrome, vocal cord paresis, wound infection) to 3% (subcutaneous hematoma).
Conclusion: Anterior cervical spine surgery is associated with a relatively high success rate and a low level of post-operative complications and it might be regarded as a safe treatment among these CSM patients who do not respond to conservative treatment.