bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybrid asynchronous sliding mode control for hidden Markovian jump systems under optimized design
Authors: Zhou Sai , Song Jun , Yang Yekai 
Published: June 2022

AbstractThis article is concerned with the hybrid design of transition rates and asynchronous sliding mode control (SMC) law for continuous‐time Markovian jump systems with matched disturbances. First, a sufficient condition is established to ensure the stochastic ultimate boundedness (SUB) of the unforced systems, which are driven only by using the designed stabilizing transition rates. Furthermore, by considering the system modes are unavailable for the controller, a hidden Markov mode detector is introduced to emit the detection modes. Based on the mode detection probabilities, a hybrid design approach is proposed by co‐designing of transition rates and asynchronous SMC law, which ensures the SUB and disturbance attenuation performance of the resulted closed‐loop systems. The obtained sufficient conditions are solved via two iterative optimization algorithms, which combine cone complementarity linearization and genetic algorithm. Finally, a numerical example with three comparison cases is provided to illustrate the proposed results.
Exploring factors affecting developer abandonment of open source software projects
Authors: Kaur Rajdeep , Chahal Kuljit Kaur 
Published: June 2022

AbstractOpen Source Software (OSS) projects have long been studied to understand the need of community support for their growth and survival. However, there has been limited research on developers' abandonment, though it is found to have detrimental effect on quality and sustainability of OSS projects. This paper examines the impact of developer and project‐related factors on developer abandonment in OSS projects. Factors include developer attributes: experience, role, coding language, and joining date, and project attributes: change complexity and sentiments in commit logs. The findings are (1) for developer experience, core/non‐core member, and joining date; there exists a pattern of developers abandoning the projects. (2) There is no definite answer for coding language. (3) It does not relate to the change profile of a project except a few indicators. Sentiments can also not be linked. These results provide OSS community and researchers with useful insights on developer abandonment and the factors influencing it or not.
A Network Analysis of L2 Motivational Factors: Structure, Connectivity, and Central Relational Links
Authors: Kiss Tamas , Pack Austin 
Published: June 2022

AbstractMotivational factors have long attracted the attention of researchers and educators with their potential to shed light on what drives effective language learning. Although current research now views language learning motivation as a Complex Dynamic System (CDS), there is a dearth of empirical studies utilizing network analysis to understand how motivational systems operate. This exploratory study investigated the structure and connectivity of a second language (L2) motivational factor network, as well as its central relational links by using network analysis and graph visualizations. Findings suggest that L2 motivational factors rarely act alone and unique communities of L2 motivational factors can be identified. Furthermore, certain factors play a central role by connecting together a multitude of other factors and act as bridges between these communities. Learners' physical and emotional states, as initial conditions in the CDS, were key factors in tying communities together. The findings also indicate that motivating and demotivating factors do not only connect with factors of similar polarity (i.e., motivating or demotivating), they are also well‐connected to each other, suggesting their interaction keeps the motivational system dynamic.
Creeping flow around a sphere placed at the axis of a circular tube filled with non‐Newtonian power‐law fluid
Authors: Pantokratoras Asterios 
Published: June 2022

AbstractThe creeping flow of a non‐Newtonian, power‐law fluid, around a sphere is considered in the present paper. The sphere is placed at the axis of a circular tube filled with non‐Newtonian power‐law fluid which moves in the tube. The problem is investigated by means of a three‐dimensional numerical simulation with the SIMPLE algorithm. The investigation covers the power‐law index from 0.2 up to 2 and tube‐to‐sphere ratio from 1.1 up to 100. For small values of the gap between the sphere and the tube the force acting on the sphere takes very high values in shear‐thickening fluids. When the tube‐to‐sphere ratio is lower or equal to 2 the force and the pressure drop increase exponentially with the power‐law index. The existing equation of Bungay and Brenner (1973) for a Newtonian fluid is very accurate for tube‐to‐sphere up to 100.
Asymptotic and Non-asymptotic Results in the Approximation by Bernstein Polynomials
Authors: Adell José A. , Cárdenas-Morales Daniel 
Published: June 2022

AbstractThis paper deals with the approximation of functions by the classical Bernstein polynomials in terms of the Ditzian–Totik modulus of smoothness. Asymptotic and non-asymptotic results are respectively stated for continuous and twice continuously differentiable functions. By using a probabilistic approach, known results are either completed or strengthened.
Die Marginalvene – nach wie vor eine seltene Entität: Fallserie von 16 Patienten
Authors: Liebetrau D. , Marnoto R. , Goßlau Y. , Zerwes S. , Stangl Franz , Wohlgemuth W. A. , Hyhlik-Dürr A. 
Published: June 2022

Zusammenfassung
Hintergrund
Die Marginalvene (MV) ist eine angeborene, vorwiegend venöse Gefäßmalformation, die auf einer fehlenden Rückbildung des embryonalen Venensystems an den unteren Extremitäten beruht. Sie geht mit einer Vielzahl an Komplikationen einher. Bisher werden in der Literatur keine einheitlichen Therapieregime beschrieben.

Fragestellung
Welche Behandlungsstrategien und Ergebnisse gibt es bei Patienten mit MV?

Material und Methoden
Im Zeitraum 01.01.2008 bis 31.12.2020 wurden alle am Universitätsklinikum Augsburg behandelten Patienten mit Marginalvene retrospektiv aufgearbeitet.

Ergebnisse
Das mediane Alter zum Diagnosezeitpunkt lag bei 14,8 Jahren (3–42 Jahre). 12/16 Patienten hatten eine Beinlängendifferenz. 75 % der Patienten (12/16) hatten bereits zur Diagnosestellung MV eine chronisch-venöse Insuffizienz (CVI). Im untersuchten Kollektiv wurden 62,5 % (10/16) der Patienten zum Zeitpunkt der Diagnosestellung mittels Kompression konservativ behandelt. Bei weiteren 31,3 % (5/16) der Patienten erfolgte primär eine offen-chirurgische Entfernung der MV und bei 1/16 Patienten wurde die MV primär mittels endovenöser Lasertherapie (EVLT) verschlossen; 15/16 Patienten wurden sekundär therapiert. 2,6 ± 2,4 (MW ± SD) Sekundärprozeduren wurden pro Patient im Follow up durchgeführt. Das mittlere Follow-up lag bei 8,1 Jahren.

Diskussion
Zur Prävention/Vermeidung einer Progression einer CVI und Thrombembolieprophylaxe sollte nach Diagnosestellung die MV zeitnah verschlossen/entfernt werden. Die Anwendung chirurgisch-konventioneller Techniken zur Entfernung der MV scheint gegenüber der Behandlung mit minimal-invasiven Prozeduren hinsichtlich der Anzahl der erforderlichen Sekundäreingriffe von Vorteil.
Swedish validation of the Pelvic Floor Questionnaire for pregnant and postpartum women
Authors: Jesberg Ute , Gutke Annelie 
Published: June 2022

Abstract
Introduction and hypothesis
The German “Pelvic Floor Questionnaire for pregnant and postpartum women” is a self-administered questionnaire customized for pregnancy and the postpartum period that assesses four domains of pelvic floor function regarding perceived symptoms, suffering, and impact on quality of life: bladder, bowel, prolapse, and sexual function. No similar questionnaire is available in Swedish, despite a high prevalence of pregnancy and postpartum pelvic floor dysfunction. Thus, we aimed to translate the validated German questionnaire into Swedish and test its validity and reliability in a Swedish population.

Methods
Translation and cultural adaptation were performed according to guidelines. Of the 248 women who answered the Swedish questionnaire, 57 filled out the questionnaire twice to evaluate test-retest reliability. We also assessed internal consistency and discriminant validity.

Results
The Swedish version of the questionnaire showed good face and content validity. Cronbach’s alpha was in the acceptable to excellent range (bladder 0.82, bowel 0.78, prolapse 0.91, and sexual 0.83), showing adequate internal consistency. A comparison of means (≥ 1 point) showed that the questionnaire significantly (p < 0.05) distinguished between women who reported suffering and those who did not. Cohen's kappa for all individual items showed fair to almost perfect agreement (0.24–0.87) between test and retest scores. The intraclass correlation coefficients for domain scores (0.92–0.97) were all in an optimal range.

Conclusions
The Swedish version of the questionnaire is a reliable and valid instrument for assessing pelvic floor disorders, symptom severity, and impact on quality of life during pregnancy and the postpartum period.
Kann man Super-Shrinks ausbilden?
Authors: Taubner Svenja , Evers Oliver 
Published: June 2022

ZusammenfassungEs werden die Ergebnisse einer von der Deutschen Forschungsgemeinschaft (DFG) geförderten längsschnittlichen Studie zur Kompetenzentwicklung von Psychotherapeut*innen in Ausbildung zusammenfassend dargestellt. Die Studie verfolgte das Ziel, die Entwicklung globaler verfahrensübergreifender Kompetenzen über einen Zeitraum von 3 Jahren zu untersuchen. Der Studie wurde das Kompetenzmodell der Bundespsychotherapeutenkammer zugrunde gelegt, das zwischen fachlichen, interpersonalen und personalen Kompetenzen unterscheidet. Die Kompetenzentwicklung wurde von Psycholog*innen zu Beginn der therapeutischen Ausbildung in kognitiver Verhaltenstherapie (KVT), tiefenpsychologisch fundierter Psychotherapie (TfP) oder Psychoanalyse (PA) im Vergleich zu einer Kontrollgruppe auf der Grundlage von Selbstberichten, Tests und Fremdauswertungen untersucht. Die Ergebnisse zeigten eine Verbesserung in Fachwissen, Fallformulierung, „healing involvement“ und der affiliativen Kommunikation mit Patient*innen, jedoch eine Stagnation und teilweise Verschlechterung im therapeutischen Arbeitserleben, in der Attributionskomplexität und der Introjektaffiliation. Veränderungen des positiven therapeutischen Arbeitserlebens wurden eher von Aspekten der Ausbildung beeinflusst, während Veränderungen im negativen therapeutischen Arbeitserleben von Aspekten der individuellen Persönlichkeit bestimmt wurden. Veränderungen im Introjekt wurden durch die Bindungsstile der Teilnehmenden erklärt. Die Studie zeigt, dass die erfolgreiche Kompetenzentwicklung durch eine stärkere Förderung globaler Kompetenzen, die als bedeutsam für das Erreichen eines Super-Shrink-Level eingeschätzt werden, ausgebaut werden könnte. Hierbei erscheinen die Aspekte Persönlichkeit und Bindungsstil als wichtige Bereiche der individuellen Förderung und einer Verringerung des ausbildungsbezogenen Stresslevels.
Bioprosthetic valve dysfunction and failure after TAVI in bicuspid aortic valve stenosis during one-year follow-up according to VARC-3
Authors: Veulemans Verena , Nuyens Philippe , Goh Shouheng , Maier Oliver , Binnebößel Stephan , Heermann Jacqueline , Jung Christian , Westenfeld Ralf , Kelm Malte , de Backer Ole , Zeus Tobias 
Published: June 2022

Abstract
Background
Transcatheter aortic valve implantation (TAVI) in bicuspid aortic valve (BAV) stenosis has become more frequent in the last years. This may pose challenges for long-time valve durability. Therefore, we aimed to evaluate the prevalence of bioprosthetic valve dysfunction (BVD) with the newest-generation devices in BAV stenosis up to one-year follow-up (FU).

Methods
The primary endpoint was defined as the prevalence of BVD during the first procedural year according to Valve Academic Research Consortium (VARC)-3 criteria. Secondary endpoints were defined as failure in device success and clinical endpoints according to VARC-3.

Results
A total of 107 patients were included. Of these, 34 subjects (31.8%) met the criteria for BVD during a mean FU of 263 ± 180 days, of which 20.2% were already documented after thirty days. Device success after one year was lower in the + BVD cohort (57.6% vs. 98.7%, p < 0.0001*). The rates of structural valve deterioration were 6.5%, non-structural valve deterioration (NSVD) 17.8%, subclinical leaflet thickening 10.3%, and endocarditis 0.9%. NSVD was foremost triggered by patient prosthesis mismatch in balloon-expandable valves. Hemodynamic valve deterioration stage 1 and 2 was confirmed in 16.8% of + BVD patients, while stage 1 and 3 bioprosthetic valve failure occurred in 1.9%. There was no impact of BVD on mortality.

Conclusion
There is critical evidence of early BVD after TAVI in BAV during one-year FU in one-third of patients, also lowering device success. The most frequently observed bioprosthetic valve dysfunction was NSVD due to patient prosthesis mismatch following TAVI with a balloon-expandable valve.
Landmark-based retrieval of inflamed skin vessels enabled by 3D correlative intravital light and volume electron microscopy
Authors: Mildner Karina , Breitsprecher Leonhard , Currie Silke M. , Stegmeyer Rebekka I. , Stasch Malte , Volkery Stefan , Psathaki Olympia Ekaterini , Vestweber Dietmar , Zeuschner Dagmar 
Published: June 2022

AbstractThe nanometer spatial resolution of electron microscopy imaging remains an advantage over light microscopy, but the restricted field of view that can be inspected and the inability to visualize dynamic cellular events are definitely drawbacks of standard transmission electron microscopy (TEM). Several methods have been developed to overcome these limitations, mainly by correlating the light microscopical image to the electron microscope with correlative light and electron microscopy (CLEM) techniques. Since there is more than one method to obtain the region of interest (ROI), the workflow must be adjusted according to the research question and biological material addressed. Here, we describe in detail the development of a three-dimensional CLEM workflow for mouse skin tissue exposed to an inflammation stimulus and imaged by intravital microscopy (IVM) before fixation. Our aim is to relocate a distinct vessel in the electron microscope, addressing a complex biological question: how do cells interact with each other and the surrounding environment at the ultrastructural level? Retracing the area over several preparation steps did not involve any specific automated instruments but was entirely led by anatomical and artificially introduced landmarks, including blood vessel architecture and carbon-coated grids. Successful retrieval of the ROI by electron microscopy depended on particularly high precision during sample manipulation and extensive documentation. Further modification of the TEM sample preparation protocol for mouse skin tissue even rendered the specimen suitable for serial block-face scanning electron microscopy (SBF-SEM).
Comprehensive bioinformatics analyses reveal immune genes responsible for altered immune microenvironment in intervertebral disc degeneration
Authors: Hai Bao , Song Qingpeng , Du Chuanchao , Mao Tianli , Jia Fei , Liu Yu , Pan Xiaoyu , Zhu Bin , Liu Xiaoguang 
Published: June 2022

AbstractWe sought to identify novel biomarkers and related mechanisms that might shape the immune infiltration in IDD, thereby providing novel perspective for IDD diagnosis and therapies. Gene expression data sets GSE124272 (for initial analysis) and GSE56081 (for validation analysis) involving samples from IDD patients and healthy controls were retrieved from the Gene Expression Omnibus (GEO) database. Immune genes associated with IDD were identified by GSEA; module genes that exhibited coordinated expression patterns and the strongest positive or negative correlation with IDD were identified by WGCNA. The intersection between immune genes and module genes was used for LASSO variable selection, whereby we obtained pivotal genes that were highly representative of IDD. We then correlated (Pearson correlation) the expression of pivotal genes with immune cell proportion inferred by CIBERSORT algorithm, and revealed the potential immune-regulatory roles of pivotal genes on the pathogenesis of IDD. We discovered several immune-associated pathways in which IDD-associated immune genes were highly clustered, and identified two gene modules that might promote or inhibit the pathogenesis of IDD. These candidate genes were further narrowed down to 8 pivotal genes, namely, MSH2, LY96, ADAM8, HEBP2, ANXA3, RAB24, ZBTB16 and PIK3CD, among which ANXA3, MSH2, ZBTB16, LY96, PIK3CD, ZBTB16, and ADAM8 were revealed to be correlated with the proportion of CD8 T cells and resting memory CD4 T cells. This work identified 8 pivotal genes that might be involved in the pathogenesis of IDD through triggering various immune-associated pathways and altering the composition of immune and myeloid cells in IDD patients, which provides novel perspectives on IDD diagnosis and treatment.
Non-negative moment fitting quadrature for cut finite elements and cells undergoing large deformations
Authors: Garhuom Wadhah , Düster Alexander 
Published: June 2022

AbstractFictitious domain methods, such as the finite cell method, simplify the discretization of a domain significantly. This is because the mesh does not need to conform to the domain of interest. However, because the mesh generation is simplified, broken cells with discontinuous integrands must be integrated using special quadrature schemes. The moment fitting quadrature is a very efficient scheme for integrating broken cells since the number of integration points generated is much lower as compared to the commonly used adaptive octree scheme. However, standard moment fitting rules can lead to integration points with negative weights. Whereas negative weights might not cause any difficulties when solving linear problems, this can change drastically when considering nonlinear problems such as hyperelasticity or elastoplasticity. Then negative weights can lead to a divergence of the Newton-Raphson method applied within the incremental/iterative procedure of the nonlinear computation. In this paper, we extend the moment fitting method with constraints that ensure the generation of positive weights when solving the moment fitting equations. This can be achieved by employing a so-called non-negative least square solver. The performance of the non-negative moment fitting scheme will be illustrated using different numerical examples in hyperelasticity and elastoplasticity.
Evaluation of the SPARTACUS-Urban Radiation Model for Vertically Resolved Shortwave Radiation in Urban Areas
Authors: Stretton Megan A. , Morrison William , Hogan Robin J. , Grimmond Sue 
Published: June 2022

AbstractThe heterogenous structure of urban environments impacts interactions with radiation, and the intensity of urban–atmosphere exchanges. Numerical weather prediction (NWP) often characterizes the urban structure with an infinite street canyon, which does not capture the three-dimensional urban morphology realistically. Here, the SPARTACUS (Speedy Algorithm for Radiative Transfer through Cloud Sides) approach to urban radiation (SPARTACUS-Urban), a multi-layer radiative transfer model designed to capture three-dimensional urban geometry for NWP, is evaluated with respect to the explicit Discrete Anisotropic Radiative Transfer (DART) model. Vertical profiles of shortwave fluxes and absorptions are evaluated across domains spanning regular arrays of cubes, to real cities (London and Indianapolis). The SPARTACUS-Urban model agrees well with the DART model (normalized bias and mean absolute errors < 5.5%) when its building distribution assumptions are fulfilled (i.e., buildings randomly distributed in the horizontal). For realistic geometry, including real-world building distributions and pitched roofs, SPARTACUS-Urban underestimates the effective albedo (< 6%) and ground absorption (< 16%), and overestimates wall-plus-roof absorption (< 15%), with errors increasing with solar zenith angle. Replacing the single-exponential fit of the distribution of building separations with a two-exponential function improves flux predictions for real-world geometry by up to half. Overall, SPARTACUS-Urban predicts shortwave fluxes accurately for a range of geometries (cf. DART). Comparison with the commonly used single-layer infinite street canyon approach finds SPARTACUS-Urban has an improved performance for randomly distributed and real-world geometries. This suggests using SPARTACUS-Urban would benefit weather and climate models with multi-layer urban energy balance models, as it allows more realistic urban form and vertically resolved absorption rates, without large increases in computational cost or data inputs.
A mixed method study of medical oncologists’ perceived barriers and motivators to addressing long-term effects in breast cancer survivors
Authors: Fauer Alex J. , Ganz Patricia A. , Brauer Eden R. 
Published: June 2022

Abstract
Purpose
The purpose of this study was to identify oncologist-reported barriers and motivators in addressing long-term effects with breast cancer survivors.

Methods
This study is a secondary analysis of data from a survey of U.S. medical oncologists (n = 217) about breast cancer survivorship care in clinical practice. Using both closed- and open-ended questions, we asked oncologists to report barriers and motivators they perceived in addressing long-term effects with breast cancer patients. Descriptive statistics were used to summarize and rank items endorsed by oncologists in analyses of quantitative data; content analysis was used to identify salient categories of barriers and motivators in qualitative data.

Results
Key barriers to managing physical long-term effects included lack of time during appointments (n = 128 oncologists, 59%) and perceived lack of evidence-based interventions (n = 89, 41%). With respect to psychosocial effects, oncologists reported lack of knowledge (n = 88, 40.6%) and challenges making referrals to mental health providers (n = 115, 53%). From the qualitative data, three distinct barrier categories emerged: “Competing priorities during brief appointments;” “Discussing long-term effects—Who? What? When?;” and “Beyond my expertise and comfort level.” Two motivator categories emerged: “I owe it to them;” and “Giving people a life worth living.”

Conclusion
Oncologists’ key motivators for addressing long-term effects were focused on professional values, relationships with survivors, and their commitment to prioritizing patients' quality of life. Future efforts should leverage oncologists' professional and interpersonal motivators to enhance the delivery of survivorship care for breast cancer.