bluuebunny/crossref_metadata_2025_split huggingface dataset:
The excellent protection effects of silicon/ytterbium silicate bilayer environmental barrier coatings on SiCf/SiC composites
Authors: Wang Yanfei , Zhang Jin , Chen Xiangjian , Wan Fan , Jian Yingjie , Liu Rongjun 
Published: July 2022

AbstractThe protection effects of an environmental barrier coating (EBC) consisting of silicon bond coat and mixed ytterbium monosilicate and ytterbium disilicate composite topcoat are directly evaluated by measuring the strength retention rate of SiCf/SiC composites completely wrapped up by the previous EBCs after soaking in a mixed oxygen and water vapor environment at 1300°C for up to 200 h. The results show that the mixed topcoat exhibits not only extremely excellent phase stability but also fantastic protection effects toward composites. After 200 h of corrosion, the fully protected composites are unveiled to present not only dramatically reduced weight gain ratios, less than .6%, compared to ∼10% for those unprotected ones, but also extremely higher strength retention rates, more than 90%, compared to only 10%–15% for those unprotected ones. Further, the fully protected composites show a quasi‐ductile load versus displacement curve, suggesting the retention of the oxidation‐prone pyrolytic carbon interphase of current composites.
Changes in miroRNA‐103 expression in wound margin tissue are related to wound healing of diabetes foot ulcers
Authors: Zhao Xiaotong , Xu Murong , Tang Ying , Xie Dandan , Wang Youmin , Chen Mingwei 
Published: July 2022

AbstractTo investigate the relationship between small noncoding microRNA‐103 (miR‐103) and wound healing of diabetic foot ulcers (DFU) and the underlying molecular mechanism, forty type 2 diabetes mellitus with DFU (DFU group), and 20 patients with a chronic skin ulcer of lower limbs and normal glucose tolerance (SUC group) were included. Quantitative real‐time PCR method was used to determine miR‐103 expression levels in the wound margin tissue of subjects, and to analyse the relationship between the expression of miR‐103 and DFU wound healing. In vitro experiments were also performed to understand the effect of miR‐103 on the high glucose‐induced injury of normal human dermal fibroblasts (NHDFs) cells. The results showed that the miR‐103 expression level in the DFU group was significantly higher than that in the SUC group [5.81 (2.25–9.36) vs 2.08 (1.15–5.72)] (P < 0.05). The expression level of miR‐103 in the wound margin tissue of DFU was negatively correlated with the healing rate of foot ulcers after four weeks (P = 0.037). In vitro experiments revealed that miR‐103 could inhibit the proliferation and migration of NHDF cells and promote the apoptosis of NHDF cells by targeted regulation of regulator of calcineurin 1 (RCAN1) gene expression in a high glucose environment. Down‐regulation of miR‐103 could alleviate high glucose‐induced NHDF cell injury by promoting RCAN1 expression. Therefore, the increased expression of miR‐103 is involved in the functional damage of NHDF cells induced by high‐glucose conditions, which is related to poor wound healing of DFU. These research findings will provide potential targets for the diagnosis and treatment of chronic skin wounds in diabetes.
Latent class analysis to characterize neonatal risk for neurodevelopmental differences
Authors: Momany Allison M. , Jasper Elizabeth , Markon Kristian E. , Nikolas Molly A. , Ryckman Kelli K. 
Published: July 2022

BackgroundNeonatal risk factors, such as preterm birth and low birth weight, have been robustly linked to neurodevelopmental deficits, yet it is still unclear why some infants born preterm and/or low birth weight experience neurodevelopmental difficulties while others do not. The current study investigated this heterogeneity in neurodevelopmental abilities by examining additional neonatal morbidities as risk factors, utilizing latent class analysis to classify neonates into groups based on similar neonatal risk factors, and including neonates from the full spectrum of gestational age.MethodsNeonates who received neonatal care at an academic public hospital during an almost 10‐year period (n = 19,951) were included in the latent class analysis, and 21 neonatal indicators of health were used. Neonatal class, sex, and the interaction between neonatal class and sex were used to examine differences in neurodevelopment at 18 months of age in a typically developing population.ResultsThe best fitting model included five infant classes: healthy, hypoxic, critically ill, minorly ill, and complicated delivery. Scores on the parent‐rated neurodevelopmental measure differed by class such that infants in the critically ill, minorly ill, and complicated delivery classes had lower scores. There was no main effect of sex on the neurodevelopmental measure scores, but the interaction between sex and neonatal class was significant for three out of five neurodevelopmental domains.ConclusionsThe current study extends the understanding of risk factors in neurodevelopment by including several neonatal medical conditions that are often overlooked and by using a person‐centered, as opposed to variable‐centered, approach. Future work should continue to examine risk factors, such as maternal health during pregnancy and medical interventions for newborns, in relation to neonatal risks and neurodevelopment by using a person‐centered approach.
Material system analysis: Functional and nonfunctional cobalt in the EU, 2012–2016
Authors: Godoy León María Fernanda , Matos Cristina T. , Georgitzikis Konstantinos , Mathieux Fabrice , Dewulf Jo 
Published: July 2022

AbstractA comprehensive data inventory of the current materials cycle in industry and society is crucial for an informed discussion and for decision‐making on the supply of raw materials. Particularly, it is key to understand how these materials are functionally and nonfunctionally recycled, and enable the assessment of recycling indicators needed for the monitoring of circular economy. In this context, a material system analysis (MSA) of cobalt for the European Union (EU) from 2012 to 2016 is presented and discussed. Detailed results are provided for the year 2016, and the evolution of the flows over time is presented from 2012 to 2016. In addition, six indicators are calculated to characterize the cobalt cycle. In 2016, the EU28 embedded around 24,000 metric tons (t) of cobalt in manufactured products, and 33,700 t were put into use. The main losses of the system are due to nonselective collection of postconsumer waste (disposed), and nonfunctional recycling of old scrap. From the years analyzed, it was possible to detect a shift in the imports; the import of primary material decreased more than 99% between 2012 and 2016, and the import of semiprocessed and processed materials increased around 31% in the same period. This indicates that after 2012, the EU became more dependent on imports in downstream stages of the supply chain. One way to decrease this dependency is to establish higher collection targets, and to establish recycling targets based on the recovery of single materials, in order to decrease the amount dissipated through nonfunctional recycling.
Lipoteichoic acid and molecular weight of hyaluronic acid could explain the late inflammatory response trigger by hyaluronic acid fillers
Authors: Moran Marta , Nieto‐Lopez Francisco , Rueda‐Carrasco Javier 
Published: July 2022

AbstractIntroductionHyaluronic acid is a safe dermal filler, but sometimes late granuloma is generated. This adverse effect is an inflammatory process, and its causes are not clear. Late granuloma generation could be due to the reaction to residual components of the bacterial wall present into hyaluronic acid, such as lipoteichoic acid (LTA). Other possibility is hyaluronic acid degraded could be trigger this inflammatory reaction.ObjectiveStudy possible molecular mechanism that could be implicated into the late granuloma formation. We wonder whereas inflammatory response activation is triggered by lower molecular weight hyaluronic acid or Gram‐positive bacterial components as LTA.MethodsWe analyzed one adverse case generated by hyaluronic acid injections. Our study with one nodule through chemical and immunofluorescence histologic technics.ResultsIn this case, observe a late granuloma without infectious process. Histological analysis shown few large Langerhans cells around fillers and multiple immunological cells infiltrated. Immunofluorescent study shown immunological cells (CD45 positives cells) with high TLR2 expression (hyaluronic acid and LTA receptor).LimitationsThe difficulty of obtaining biopsy samples of nodules implies that the number of cases analyzed is very low.ConclusionNew model is proposed in which weight of hyaluronic acid and LTA could be able to trigger inflammation. This process could be mediated by TLR2 expressed in infiltrated immune cells.
Authenticity, meaning in life, and life satisfaction: A multicomponent investigation of relationships at the trait and state levels
Authors: Lutz Paul K. , Newman David B. , Schlegel Rebecca J. , Wirtz Derrick 
Published: July 2022

AbstractObjectiveThe present study sought to examine: (1) how the components of authenticity (i.e., authentic living, self‐alienation, accepting external influence) relate to one another at between‐ and within‐person levels of analysis; (2) how the authenticity facets relate to meaning in life (i.e., purpose, comprehension, mattering) and life satisfaction at these levels of analysis; and (3) whether these relationships persist when controlling for affect and self‐esteem.MethodCanadian undergraduates (N = 203) completed a trait questionnaire and end‐of‐day reports on these constructs for two weeks (n = 2335).ResultsAt between‐ and within‐person levels, authentic living was negatively associated with self‐alienation and accepting external influence, while the latter two facets were positively associated. Authentic living was positively related to well‐being and predicted greater well‐being the following day. Alternatively, self‐alienation and accepting external influence were negatively related to well‐being, and self‐alienation predicted lower well‐being the following day. Relationships involving authentic living and self‐alienation were more robust than those involving accepting external influence.ConclusionExtending research on authenticity beyond between‐person relationships, our findings show that daily states of authenticity predict well‐being in nuanced ways, depending on the facet of authenticity. This highlights the importance of distinguishing levels of analyses and facets of authenticity.
#Insta personality: Personality expression in Instagram accounts, impression formation, and accuracy of personality judgments at zero acquaintance
Authors: Osterholz Sarah , Mosel Emily I. , Egloff Boris 
Published: July 2022

AbstractObjectiveThis study examined personality expression, impression formation, and the consensus and accuracy of zero‐acquaintance personality judgments that were based on people's Instagram accounts.MethodSelf‐ and informant reports of the Big Five personality traits, self‐esteem, and narcissism were collected for 102 Instagram users. Screenshots were taken of Instagram users' profiles, including up to the 102 latest available Instagram posts. A number of Instagram cues were objectively retrieved, counted, and rated by independent trained cue coders from the screenshots. 100 unacquainted observers then judged the Big Five traits, self‐esteem, and narcissism on the basis of Instagram screenshots only.ResultsWe identified Instagram account characteristics that were associated with users' personality traits (measured with self‐reports, informant reports, and self‐informant composites) and observers' zero‐acquaintance personality judgments. Personality judgments that were based on Instagram accounts demonstrated consensus and significantly converged with Instagram users' Big Five traits, self‐esteem, and narcissism across all three personality criteria. Averaged‐observer accuracy correlations for self‐informant composite scores ranged from r = .44 (p < .001) for extraversion to r = .25 (p = .013) for conscientiousness.ConclusionsOur findings provide insight into cue processes of online self‐portrayal and impression formation on Instagram and the level of zero‐acquaintance accuracy.
Pyroptosis may play a crucial role in modifications of the immune microenvironment in periodontitis
Authors: Chen Hang , Wang Zhenxiang , He Yujuan , Peng Limin , Zhu Junlin , Zhang Xiaonan 
Published: July 2022

AbstractBackground and objectivePublished studies proved that both pyroptosis and periodontitis owned a substantial relationship with immunity, and recent research revealed a solid correlation between periodontitis and pyroptosis. While abundant findings have confirmed pyroptosis has a strong impact on the tumor microenvironment, the function of pyroptosis in influencing the periodontitis immune microenvironment remains poorly understood. Thus, we aimed to identify pyroptosis‐related genes whose expression signature can well discriminate periodontitis from healthy controls and to comprehend the role of pyroptosis in the periodontitis immune microenvironment.Materials and methodsThe periodontitis‐related datasets were acquired from the Gene Expression Omnibus (GEO) database. A series of bioinformatics analyses were conducted to investigate the underlying mechanism of pyroptosis in the periodontitis immune microenvironment. Infiltrating immunocytes, immunological reaction gene sets, and the human leukocyte antigen (HLA) gene were all investigated as potential linkages between periodontitis immune microenvironment and pyroptosis.ResultsTwenty‐one pyroptosis‐related genes were dysregulated. A four‐mRNA combined classification model was constructed, and the receiver operating characteristic (ROC) curve analysis demonstrated its prominent classification capabilities. Subsequently, the mRNA levels of the four hub markers (CYCS, CASP3, NOD2, CHMP4B) were validated by quantitative real‐time PCR (qRT‐PCR). The correlation coefficients between each hub gene and immune characteristics were calculated, and CASP3 exhibited the most significant correlations with the immune characteristics. Furthermore, distinct pyroptosis‐related expression patterns were revealed, along with immunological features of each pattern. Afterward, we discovered 1868 pyroptosis phenotype‐related genes, 134 of which were related to immunity. According to the functional enrichment analysis, these 134 genes were closely related to cytokine signaling in immune system, and defense response. Finally, a co‐expression network was constructed via the 1868 gene expression profiles.ConclusionFour hub mRNAs (CYCS, CASP3, NOD2, and CHMP4B) formed a classification model and concomitant results revealed the crucial role of pyroptosis in the periodontitis immune microenvironment, providing fresh insights into the etiopathogenesis of periodontitis and potential immunotherapy.
Semantic reasons
Authors: Cumming Samuel 
Published: July 2022

AbstractAn analysis of a predicate normally takes the form of a condition that is both necessary and sufficient for the predicate's application. Here I consider the idea, due originally to Friedrich Waismann, that semantic analyses might include conditions that are defeasible, and so allow for exceptions. Analyses of this sort can be expressed in nonmonotonic logic, a post‐Waismann development. I'll argue that defeasibility makes analysis tractable, without making it trivial. I'll also show that a defeasible account of vague predicates can predict our intuitions about particular cases (for instance, that a seven‐foot person counts as tall) without drawing artificial boundaries.
Theorising labour unrest and trade unionism in the platform economy
Authors: Joyce Simon , Stuart Mark , Forde Chris 
Published: July 2022

AbstractThe article develops a novel conceptualisation of labour unrest and trade unionism in the platform economy, extending current understandings in two ways. First, we situate platform work historically, in thelongue duréeof paid work under capitalism. Secondly, we introduce a consideration of social structure into debates on union practices often framed in terms of agency. Building on Silver and the Webbs, we highlight the importance in platform work of associational power over structural power; legal enactment over collective bargaining; and geographical over workplace unionism. While mainly a theoretical article, we draw on empirical evidence from research into platform work over five years, comprising interviews, case study, observation and documentary analysis. We conclude that platform labour unrest and unionism bear marked similarities with 19th century forms rather than the 20th century models that often dominate industrial relations perspectives. Consequently, unions organising platform workers should consider adapting their approach accordingly.
Global studies and human geography: A view from Aotearoa New Zealand
Authors: Gillen Jamie 
Published: July 2022

AbstractThis article introduces global studies to an Aotearoa New Zealand audience with the goal of thinking through what human geographers might learn by comparing elements of global studies with their own discipline. It begins by reviewing global studies and its establishment at The University of Auckland and then considers how global studies relates to human geography. A number of areas of mutual benefit are identified. The relationship between global studies and human geography is important to consider during a time of change within higher education in Aotearoa, a point discussed in the conclusion.
Progression of Spinal Ligament Ossification in Patients with Thoracic Myelopathy
Authors: Zhai Jiliang , Guo Shigong , Li Jiahao , Chen Bingrong , Zhao Yu 
Published: July 2022

ObjectiveTo evaluate the rate of increase in thickness and cross‐section area (CSA) of the ossification in thoracic myelopathy with or without cervical and lumbar spinal ligament ossification.MethodsA total of 24 patients with 170 segments (47 ligamentum flavum [OLF] and 123 cases of ossification of the posterior longitudinal ligament [OPLL]) of spinal ligament ossification between January 2012 and March 2019 at a single institution were retrospectively reviewed. Demographic data, classification of OPLL, Sato classification of OLF, pre‐ and postoperative neurological function and complications were recorded. The thickness and CSA at the segment of maximum compression were measured with Image J software on the axial CT image.ResultsTwelve female and 12 male patients with thoracic myelopathy and spinal ligament ossification were enrolled in the study. The mean age of the patients was 54.0 ± 11.9 years with an average follow‐up of 22.2 ± 23.5 months. Overall, the mean rate of progression in thickness and CSA was 1.2 ± 1.6 and 18.4 ± 50.6 mm2/year, respectively. Being female, aging (≥45 years), and lower BMI (<28 kg/m2) predisposed patients to have faster ossification growth in thickness and CSA. The difference between the rate of OPLL and OLF progression in thickness and CSA was not significant. However, the rate of OPLL progression in the thoracic spine was significantly higher than that in the cervical spine regarding thickness (1.4 ± 1.9 vs. 0.6 ± 0.7 mm/year) and CSA (27.7 ± 72.0 vs. 7.3 ± 10.3 mm2/year).ConclusionThis is the first study to investigate ligament ossification progression in patients with thoracic myelopathy. The difference between the rate of OPLL and OLF progression in thickness and CSA was not significant. However, the rate of thoracic OPLL progression in thickness and CSA was significantly higher than that in the cervical spine.
Role of extracellular vesicles in intercellular communication during reproduction
Authors: Godakumara Kasun , Dissanayake Keerthie , Hasan Mohammad Mehedi , Kodithuwakku Suranga. P. , Fazeli Alireza 
Published: July 2022

AbstractThe mammalian reproduction is a process of controlled cellular growth and development regulated by constant communication between the gametes, the subsequent embryo and the maternal system. Extracellular vesicles (EVs) are involved in these communications to a significant degree from the gamete production and maturation to fertilization, embryo development and implantation. They regulate the cellular physiology and the immune reaction to bring about a favourable environment for a successful pregnancy. Deciphering the mechanisms employed in EV‐mediated embryo maternal communication could improve our knowledge in mammalian reproduction and increase the efficiency of animal breeding.
Revised Attentional Fixation on Suicide Experiences Questionnaire and its relationship with suicidal ideation and behavior: A cross‐sectional study
Authors: Mandel Abby Adler , Revzina Olga , Jessani Zohaib , Brown Gregory K. 
Published: July 2022

AbstractIntroductionThe Attentional Fixation on Suicide Experiences Questionnaire (AFSEQ) was developed to measure attentional fixation on suicide, a cognitive process characterized by a preoccupation with suicide as a solution. This study investigated a revised version (AFSEQ‐R) and examined differences between those who made a recent suicide attempt and those with suicidal ideation (SI).MethodParticipants were 57 inpatients who attempted suicide within 14 days of study participation and 57 inpatients who presented with SI but no suicidal behavior within the past year. Analyses examined the internal reliability, multidimensionality, and construct validity of the AFSEQ‐R, and whether attentional fixation moderated the correlation between SI and attempt status.ResultsExploratory factor analysis revealed a two‐factor structure, and subscale and total scores demonstrated excellent internal consistency. Cognitive Stuckness (and total score) correlated with SI, anxiety, impulsivity, and specific problem‐solving deficits, while Cognitive Dysfunction correlated with anxiety and acted as a moderator of the correlation between Stuckness and SI. AFSEQ‐R scores did not moderate the relationship between SI and attempt status.ConclusionAFSEQ‐R is a psychometrically sound and valid measure of attentional fixation. Attentional fixation on suicide is correlated with SI, and prospective studies are needed to uncover its directional effect on suicidal crises.
Patient ABO blood type is a major predictor of a positive DAT following a transfusion reaction
Authors: Schnieders Eric , Leon Judith , Chapman James M. , Knudson C. Michael 
Published: July 2022

AbstractBackgroundA direct antiglobulin test (DAT) checks for antibody or complement on the surface of RBCs and is often done following a transfusion reaction. While passive anti‐A and anti‐B antibodies are known to cause positive DATs, the extent this occurs following transfusion is unknown.Study Design and MethodsDAT results, ABO type, eluate information, and blood product information were recorded on 1097 transfusion reactions at a large academic hospital over 8 years. The effect of patient blood type, product type, and plasma compatibility of blood product transfused on DAT results were determined. Statistical significance was determined using Chi‐squared testing.ResultsPatient ABO blood type was a strong predictor of a positive DAT, with type O patients having 6.7% positive rate and non‐O patients having a positive rate of 20.6% (p < .0001). Plasma compatibility of the product was a strong predictor of a positive DAT, with plasma compatible transfusions having a 9.4% positive rate while plasma incompatible transfusions were positive 44% of the time (p < .0001). Elution studies found that anti‐A/B antibodies were the most common antibody identified. Platelets were more likely to be associated with a positive DAT when compared with RBC transfusions (p < .05).ConclusionsThese results demonstrate the patient ABO type and plasma incompatibility are strong predictors of positive DAT results following a transfusion reaction. Anti‐A and anti‐B antibodies are estimated to account for about 50% of positive DATs in this study.