bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical simulation of nanofluid flow between two parallel disks using 3-stage Lobatto III-A formula
Authors: Alotaibi Hammad , Rafique Khuram 
Published: July 2022

Abstract
The development of nanofluid technology has become a key research area in physics, mathematics, engineering, and materials science. Nowadays, in many industrial applications, nanofluids are widely used to enhance thermophysical properties such as thermal diffusivity, thermal conductivity, and convective heat transfer. Scientists and engineers have established interests in the direction of flow problems developed via disk-shaped bodies. There are various logics to discuss flow phenomenon due to rotating bodies, but its applications include in thermal power engineering system, gas turbine rotors, air cleaning machines, aerodynamics, etc. Nowadays manufacturing industries have inaugurated to select liquid based on heat transfer properties. Therefore, this article focuses on studying the laminar incompressible nanofluid between two parallel disks. Mathematical formulations of the law of conservation of mass, momentum, and heat transfer are investigated numerically. By using suitable similarities, the flow equations are converted into nonlinear ordinary differential equations. The resulting equations were solved numerically via MATLAB software. The effects of physical parameters of interest, such as Reynolds number, magnetic factor, Brownian parameter, and thermophoresis parameter on normal velocity, streamwise velocity, temperature, and concentration profiles are computed and presented using the graphs. The results revealed that the energy profile significantly rises, and the profile moves closer to the upper disk by enhancing the Brownian motion and thermophoresis parameter. The dynamics behind this is that by increasing the Brownian motion, the boundary layer wideness increases which increases the temperature. Moreover, streamwise velocity increases for large values of Reynolds number. Besides, the thermophoresis profile increases for large values of the thermophoresis factor. It could be observed that shear stress at nonporous/porous disk is adjusted by selecting a suitable value of injection velocity at the porous disk. Also, normal velocity decreases by increasing the parameter M.
Policijos pareigūnų darbo aplinkoje patiriamo streso ypatumai, jų analizė
Authors: Jeriomenkaitė Aistė , Zakaraitė Agnė , Strukčinskienė Birutė , Pačiauskaitė Ineta , Mažrimienė Gražina , Strazdienė Neringa 
Published: July 2022

Policininkų psichoemocinė būsena, jų patiriamo streso darbe ypatumai, streso valdymas yra aktualios visuomenės sveikatos problemos. Darbe patiriamas stresas gali lemti pareigūnų atliekamo darbo kokybės prastėjimą, prastą darbo funkcijų atlikimą. Straipsnyje keliamas tyrimo tikslas – policijos pareigūnų darbe patiriamo streso analizė. Tyrime dalyvavo 138 Lietuvos komisariatų policijos pareigūnai. Atliktas kiekybinis tyrimas, apklausa raštu. Naudota SPSS programa, taikytas chi kvadrato kriterijus. Duomenys reikšmingi, kai p ≤0,05. Tyrimas atskleidė, kad policijos pareigūnams reikėtų kurti palankesnę, saugesnę ir sveikesnę darbo aplinką, vis dar trūksta vadovų palaikymo ir pasitikėjimo jais.
Duplex Labeling and Manipulation of Neuronal Proteins Using Sequential CRISPR/Cas9 Gene Editing
Authors: Droogers Wouter J. , Willems Jelmer , MacGillavry Harold D. , de Jong Arthur P. H. 
Published: July 2022

AbstractCRISPR/Cas9-mediated knock-in methods enable the labeling of individual endogenous proteins to faithfully determine their spatiotemporal distribution in cells. However, reliable multiplexing of knock-in events in neurons remains challenging because of cross talk between editing events. To overcome this, we developed conditional activation of knock-in expression (CAKE), allowing efficient, flexible, and accurate multiplex genome editing. To diminish cross talk, CAKE is based on sequential, recombinase-driven guide RNA (gRNA) expression to control the timing of genomic integration of each donor sequence. We show that CAKE is broadly applicable in rat neurons to co-label various endogenous proteins, including cytoskeletal proteins, synaptic scaffolds, ion channels and neurotransmitter receptor subunits. To take full advantage of CAKE, we resolved the nanoscale co-distribution of endogenous synaptic proteins using super-resolution microscopy, demonstrating that their co-organization correlates with synapse size. Finally, we introduced inducible dimerization modules, providing acute control over synaptic receptor dynamics in living neurons. These experiments highlight the potential of CAKE to reveal new biological insight. Altogether, CAKE is a versatile method for multiplex protein labeling that enables the detection, localization, and manipulation of endogenous proteins in neurons.
Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications
Authors: Ghzaiel Imen , Sassi Khouloud , Zarrouk Amira , Ghosh Shubhrima , Dias Irundika H K , Nury Thomas , Ksila Mohamed , Essadek Soukaina , Tahri Joutey Mounia , Brahmi Fatiha , Mihoubi Wafa , Rup-Jacques Sandrine , Samadi Mohammad , Rezig Leila , Meziane Smail , Ghrairi Taoufik , Masmoudi-Kouki Olfa , Hammami Sonia , Nasser Boubker , Hammami Mohamed , Wang Yuqin , Griffiths William J , Vejux Anne , Lizard Gérard 
Published: July 2022

Graphical abstract

Abstract
7-Ketocholesterol (or 7-oxocholesterol) is an oxysterol essentially formed by cholesterol autoxidation. It is often found at enhanced levels in the body fluids and/or target tissues of patients with age-related diseases (cardiovascular, neuronal, and ocular diseases) as well as in subjects concerned with civilization diseases (type 2 diabetes, bowel diseases, and metabolic syndrome). The involvement of increased 7-ketocholesterol levels in the pathophysiology of these diseases is widely suspected. Indeed, 7-ketocholesterol at elevated concentrations is a powerful inducer of oxidative stress, inflammation, and cellular degeneration which are common features of all these diseases. It is important to better know the origin of 7-ketocholesterol (diet, incidence of environmental factors, and endogenous formation (autoxidation and enzymatic synthesis)) and its inactivation mechanisms which include esterification, sulfation, oxidation, and reduction. This knowledge will make it possible to act at different levels to regulate 7-ketocholesterol level and counteract its toxicity in order to limit the incidence of diseases associated with this oxysterol. These different points as well as food and biomedical applications are addressed in this review.
El derecho humano a la educación primaria ante el COVID-19, en Tecpan de Galeana, Guerrero, México
Authors: Ramírez Izazaga Cinthia 
Published: July 2022

The purpose of this article is to show the challenges and difficulties faced by primary school students in the municipality of Tecpan de Galeana, Guerrero, derived from the COVID-19 pandemic, since they have been significantly affected, because the Mexican State has been overwhelmed by the negative effects of the pandemic, and with it, various students have not been able to access or continue their education. The research is of a socio-legal type, due to the level and timing of the research carried out, it is descriptive, for the purpose is that of applied research, the inductive method was used and the paradigm used is the interpretive one. The techniques and instruments used were: data collection directly from reality, surveys and interviews, books, legislation, jurisprudence, magazines, among others. To do this, we will get to know what the reality is like for primary school children who reside in said municipality, in the same way we will get to know the measures that the Mexican State has taken in this regard and how effective they have been. In addition, all the recommendations made by various international organizations will be consulted. Among the main conclusions, it was found that undoubtedly the human right to primary education is a human right recognized not only by international organizations, but also by the Political Constitution of Mexico, as well as by State constitutions and laws. Therefore, the State has the obligation to comply with guaranteeing this human right. It was concluded that the Mexican State did not know how to take the appropriate measures, and did not invest enough to face the difficulties that arose in educational matters as a result of the COVID-19 pandemic. In addition to this, many parents were unable to pay for the various expenses involved in distance education, due to the unemployment that was triggered by the pandemic.
La deconstrucción del enemigo: Aportes para edificar la paz en Colombia
Authors: Ballesteros Guerrero Elkin Aleixi , Inampués Borda Andrés Ricardo , Rivera Gómez Andrés Felipe 
Published: July 2022

This article presents the results of an investigation where the construction of the enemy was analyzed from educational contexts in Colombia. The methodology used was action research (AR) using interviews that, from the critical discourse analysis (CDA), allowed to evidence some practices and discourses that establish imaginaries about the other being, which in the end helped to understand the need to promote new strategies that allow the deconstruction of these practices that facilitate processes to strengthen the development of peace, achieve greater bonding between family and the educational sphere, and link the social whenimplementing a pedagogical strategy that favors a culture of stronger peace from the territories.
Correlation Between Allergy History in Family and Allergy Manifestation in School Age Children
Authors: Mahrunnisa Fitria , Sumadiono Sumadiono , Mulatsih Sri 
Published: July 2022

Background: Asthma, eczema and allergic rhinitis are influenced by both genetic factor and environtment factors. Based on family history of allergy, allergic trace cards can identify the level of allergic risk in children. The relationship between family history of allergy and manifestation of allergic disease as a single allergy disease and allergic multimorbidity still need to be explored. The objective of this study was to identify the associations between family history of allergic disease and manifestation of allergic disease in school-age children.Methods: We conducted a cross sectional study on school age children with 6-13 years old at eight elementary schools in Yogyakarta. Family history of allergy was defined as reported asthma, eczema and allergic rhinitis in a parent or sibling and classified the level of allergic risk based on allergic trace cards. Subjects were questioned by standardized ISAAC questionnaire. The relationship between the two was analyzed by the Chi-squared analysis to assess the prevalence ratio (PR).Results: A total of 272 children with an average age of 8.4 years, allergic manifestations occurred more as multimorbidity (53%) with the highest incidence of RA+asthma (9%) compared with one allergic disease (47%) with the highest incidence of RA (11%). There was a significant relationship between family history of allergy and all manifestations of allergic disease with an increased risk of developing allergies by 3.3 (PR 3.3; 95% CI 2.3-4.8) and 2.8 times (PR 2.8; IK95% 1.8-4.3) in the moderate and high-risk score group. Asthma, RA and DA have a risk for coexistence with 2 other diseases of 2.5 (RP 2.5 IK95%; 1.9-3), 2.25 (PR 2.25 IK95%; 1.7 -3) and 1.9 times (PR 2.5 IK95%; 1.45-2.4).Conclusion: Family history of allergic disease is a risk factors for the development of allergic manifestation both a single allergic disease and multimobidity.
The importance of digitalization and robotization in vehicle production in the European Union
Authors: Török László 
Published: July 2022

AbstractVehicle manufacturing is an industry in which the technologies used by Industry 4.0 and their evolution can best be traced. Digitalization-robotization is paramount to the technical methods used in the Fourth Industrial Revolution. The question is how close a correlation between productivity and digitalization robotics in vehicle production is in the Member States of the European Union. I perform the relationship between the two variables by correlation calculation. Then I classify the member states according to the closeness of the relationship between the two variables using the method of hierarchical cluster analysis. Empirical results show a robust relationship, with the highest per capita production value in those Member States with the highest degree of digitalization-robotization in vehicle production. In conclusion, the countries in Central and Eastern Europe and the end of the productivity rankings need to increase the degree of digitalization of their vehicle production to increase their productivity and competitiveness.
News of the 90th Congress of the European Society of Atherosclerosis (EAS), Milan May 21-25, 2022
Authors: Yezhov M. V. 
Published: July 2022

С 21 по 25 мая 2022г в г. Милане (Италия) в гибридном формате прошел 90-й конгресс Европейского общества атеросклероза (EAS).
Suspensión al ejercicio de los derechos a la libertad de tránsito y de reunión en el marco de la pandemia por covid-19
Authors: Hernández-López Luís Ernesto 
Published: July 2022

La pandemia por sars-CoV-2 (covid-19) ha supuesto un reto no solo para el sistema social, sanitario y económico del Estado mexicano, sino también para su respectivo sistema jurídico y para la garantía de los derechos humanos reconocidos por su Carta fundamental en favor de todas las personas. Pues en aras de garantizar la seguridad, la salud y la contención del virus, los distintos niveles de organización política (federal, estatal y municipal) han optado por la emisión de medidas que afectan el pleno goce y ejercicio de prerrogativas como la libertad de reunión y de tránsito.
Sin embargo, para que aquellas medidas se consideren legítimas, deben efectuarse en el marco de una situación excepcional para la vida de un país; y cumplir con los requisitos y con los estándares normativos previstos por el artículo 29 de la Constitución Política de los Estados Unidos Mexicanos, así como por el ordinal 27 de la Convención Americana sobre los Derechos Humanos. Condiciones generales que abordaremos de conformidad con los criterios establecidos en la jurisprudencia interamericana, desde una perspectiva teleológica de esos preceptos, con la intención de dilucidar el contexto jurídico y social en que las referidas libertades serían susceptibles de suspensión.
Visibilización de personas con discapacidad en Cúcuta
Authors: Vanegas Sáenz Héctor Daniel , Rodríguez Peña Alejandra del Mar 
Published: July 2022

Introducción: el concepto de inclusión social está ligado al de equidad, ya que permite el empoderamiento, la vinculación y la participación de todas las personas en la vida social, económica y política del país. Lograr que las personas con discapacidad alcancen la plena integración, reconozcan sus potencialidades y no se les encasille en su déficit es un compromiso que debe ser respaldado desde las políticas públicas del país, las cuales deberán incentivar la transformación cultural.
Metodología: durante los años 2017 y 2018, se organizaron dos ediciones de la Feria de la Inclusión en las que se invitó a diferentes instituciones de la ciudad de Cúcuta que trabajan en pro de las personas con discapacidad y a diez empresas privadas. En la segunda versión de la feria, se aplicó una encuesta a 465 personas asistentes, dándole un enfoque descriptivo y deductivo al estudio.
Resultados: se percibe una gran aceptación en torno al concepto de inclusión laboral por parte de los encuestados, pues más del 98% de ellos manifestó estar de acuerdo con brindar oportunidades laborales a personas con discapacidad.
Conclusiones: este proyecto ha contribuido a la identificación de puntos que hay que revisar para llevar a cabo procesos de inclusión social y laboral de personas con discapacidad.
The Yoga Instructor Beliefs Scales Epistemic (YIBS-E) and Pedagogic (YIBS-P): Development and Initial Assessment of the Factor Structure
Authors: Reeves Tegan Jemma , Harrell-Williams Leigh , Khalsa Sat Bir Singh , Mueller Christian E. , Groessl Erik 
Published: July 2022

Abstract
Yoga is a multidimensional and heterogeneous mind-body practice led by a therapist or teacher (e.g., yoga instructor). Although they constitute an integral part of delivery, content, and curriculum, factors that influence yoga instructors’ choices have yet to be explored. Using a mixed methods sequential design for development of an instrument that identifies measurable epistemic (YIBS-E) and pedagogic (YIBS-P) beliefs, the Yoga Instructor Beliefs Scale (YIBS) reports validity evidence from four distinct phases. Phase I presents qualitative findings from literature-informed semistructured interviews to give a comprehensive construct model of yoga instructor beliefs from diverse styles/ schools/lineages of yoga (nine content-specific clusters). In Phase II, focus group panels of experts evaluated construct novelty and importance of themes, resulting in a pool of potential questionnaire items. Phase III employed cognitive interviews to assess the perceived meaning and clarity of using the preliminary YIBS items. Phase IV included exploratory factor analysis and correlational analyses using 204 yoga instructor responses, suggesting a 44-item instrument with distinct epistemic (Experiential, Energetic, Systems-Based, Affectual, Mindful, and Physical) and pedagogic (Curricular Integration, Student Awareness, Accessibility, and Differentiated Instruction) factors (YIBS- E α = 0.90, YIBS-P α = 0.85). Measurable belief constructs can inform research on individual yoga instructor differences that may influence curriculum content choices and delivery. The purpose of this instrument is to enable research linking instructor beliefs to the presence of various components of a yoga program and to contextualize defining qualities of yoga programs. Long-term use of this instrument should enable in-depth analyses such as mediation or moderation of yoga instructor beliefs on intervention components/content or outcomes.
Traffic congestion prevention system
Authors: TOULNI Hamza , MIYARA Mounia , NSIRI Benayad , BOUDHANE Mohcine 
Published: July 2022

Transport is one of the key elements in the development of any country; it can be a powerful catalyst for economic growth. However, the infrastructure does not give enough to the huge number of vehicles which produces several problems, particularly in terms of road safety, and loss of time and pollution. One of the most significant problems is congestion, this is a major handicap for the road transport system. An alternative would be to use new technologies in the field of communication to send traffic information such as treacherous road conditions and accident sites by communicating, for a more efficient use of existing infrastructure. In this paper, we present a CPS system, which can help drivers in order to have a better trip. For this raison we find the optimal way to reduce travel time and fuel consumption. This system based on our recent work [1]. It´s new approach aims to avoid congestion and queues, hat assure more efficient and optimal use of the existing road infrastructure. For that we concentrate by analyzing the useful and reliable traffic information collected in real time. The system is simulated in several conditions, Experimental result show that our approach is very effective. In the future work, we try to improve our system by adding more complexity in our system.
Inflammatory cell distribution accrediting Th2 inflammation in Sinonasal polyp in Indian Population
Authors: Singh Rakesh Kumar , Kumari Priyanka , Singh Reecha , Mishra Sarita Kumari , Kumar Prateek , Prakash Piyush 
Published: July 2022

The pathophysiology of Chronic Rhino-Sinusitis with Nasal Polyposis (CRSwNP) showed distinct ethnic and geographic differences whereas the Western Caucasian population revealed Th2 eosinophilic inflammation in contrary to the Asian Mongolian population with Th1-Th17 non-eosinophilic inflammatory pattern. Prospective Observational study was undertaken from December 2019 to December 2021 on 50 patients who were diagnosed to have sinonasal polyposis. The collected polyp tissue was sent to the histopathological department for further microscopic evaluation. The types of inflammatory cell infiltrate studied in the tissue specimens obtained during surgery included lymphocytes, eosinophils, neutrophils, mast cells, and plasma cells. The age of patients ranged from 11 to 70 years with a mean age of 31.80±17.69 years. The male to female ratio was 1.3:1. The 62% of patients showed the predominance of eosinophil which was of grade III and grade IV category, Lymphocyte infiltrate of grades III and IV was present in 46% of cases, Mast cell was 30% and 10% of grade III and Grade IV respectively, and the Neutrophils were found only in 22% and 105 of cases of grade III & Grade IV, respectively which was the least of all inflammatory cells found in polyp tissue. The cellular predominance was shifted toward the Th2 type of inflammation with the predominance of Eosinophil, Lymphocytes, Plasma cells, and mast cells in the Asian Aryan sub origin population contrary to the Th17 type of inflammation as indicated by the least infiltration of Neutrophils as reported in Asian Mongolian Populations.
The THE EFFECT OF LEARNING NAHWU SHOROF IN PONDOK PESANTREN TOWARD STUDENT UNDERSTANDING OF ARABIC
Authors: Falihah Fina Aimmatul , Mahirah Maulida Afra 
Published: July 2022

The Effect of Learning Nahwu Sorof in Pondok Pesantren toward Student Understanding of Arabic
Arabic language education students at UIN Salatiga have the same courses as the material obtained at Islamic Boarding Schools. One of them is the Nahwu Shorof course. Based on the observations that have been made, the teaching methods between the two educations have several differences that cause the level of understanding of students to also differ. As in Islamic boarding schools, the method used is the book method where the method is sourced directly from Arabic-language books. From this method, students can get several skills at once in one type of lesson, namely when studying it students not only take the core of the material being taught but can also expand their vocabulary through explanations of the material available in Arabic. From this, students are able to implement and practice directly the nahwu shorof material they get.
On the other hand, the teaching method at the university almost all lecturers only convey the translation without interpreting the Arabic material one by one. So that students only understand the core material of nahwu shorof learning without being able to implement it directly because explanations are already available in different languages.
Keywords: Education , Learning, Teaching Methods, Language, Islamic