bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effects of Turmeric Powder Addition in Fish Feed toward Hematology of Common Carp (Cyprinus carpio)
Authors: Pridayem Putri , Windarti Windarti , Fitria M Dian 
Published: November 2022

Turmeric (Curcuma longa) contains curcumin that can be used to improve the health as well as the immune system of the fish. The health and immune system condition of the fish can be predicted based on the hematology of the fish. A study that aims to understand the effects of turmeric addition in fish feed pellets on the hematology condition of common carp has been conducted from March to May 2022. The turmeric powder was mixed well with the feed pellets and the dosages of the turmeric powder were as follows: 0 (Control, no turmeric addition), P1 (0.5 g/kg), P2 (1 g/kg), and P3 (1.5 g/kg). The fish was reared in circular plastic containers (25 L), completed with an aerator and circulation pump) for 49 days, 15 fish/ container. During the research, the fish was fed 3 times/ day, at satiation. Samplings were conducted 2 times before the treatment was applied and by the end of the experiment (the 49th day). Results show that the addition of turmeric powder in the fish feed pellets clearly affects the hematological of the fish. Fish that was fed with turmeric-enriched pellets showed a higher percentage of lymphocyte and which means that the immunity of the fish is improved. The best treatment P3 showed 81.55% lymphocyte, 6.55% monocyte, 5.44% neutrophil, and 5.44% thrombocyte. Data obtained indicate that the fish fed with turmeric pellets perform better in hematological conditions than the fish with no turmeric-enriched pellets.
Growth Performance of Striped Catfish (Pangasianodon hypopthalmus) Fed by Fermented Water Hyacinth
Authors: Ramayani Santi , Suharman Indra , Lukistyowati Iesje 
Published: November 2022

Fermented water hyacinth by Aspergillus niger can be used as alternative ingredient replacing soymeal for feed in striped catfish. The experimental designed consist of five treatment substitution of soymeal used fermented water hyacinth and three repliacate: T0 (feed without FWH); T1 (25% FWH); P2 ( 50% FWH); P3 (75% FWH); and P4 (100% FWH. ). A total of 375 Striped catfish weight 4.21 ± 0.42 g were stocked with a density of 25 fish m-3 in fixed net cages. The study was conducted for 42 days. The results showed that the treatment given improved growth, feed convertion, and survival rate of striped catfish at dose FWH 50% It is recommended that substitution FWH 50% can used to replacing soymeal for feed striped catfish
A South Indian Cadaveric Study on the Prevalence of Gallstones
Authors: Nayak S. B. , Soumya K. V. 
Published: November 2022

Background Gallstone disease (GSD) is one among the most prevalent diseases that affects approximately 10-15% of the population. It is associated with many other diseases like gallbladder cancer, renal stones, atherosclerosis, coronary heart disease and stroke.
Objective Objective of this study is to document the prevalence of gallstones among south Indian cadavers.
Method One hundred and twenty three South Indian cadaveric livers/gallbladders were observed for the presence of gallstones. The age range was 40 to 70 years. The gallbladders were palpated to know the presence of stones. They were then dissected and the stones were classified based on appearance. Gall bladder walls were also observed to know the associated fibrosis.
Result Among the cadavers studied, 0.81% possessed cholesterol stones and 4.06% had pigment stones. Among the stones, 83.33% were pigment stones and 16.66% were cholesterol stones.
Conclusion Compared to the western countries and north Indian studies, the prevalence of gallstone disease is low in the south Indian population (4.87%). The low prevalence was probably due to the low socioeconomic status and the diet and lifestyle.
Microalbuminuria as a Predictor of Pre-eclampsia in Pregnant Women Presenting in the Antenatal Clinic at Dhulikhel Hospital
Authors: Dongol A. , Timilsina N. , Bastakoti R. , Bhatta R. D. , Risal P. 
Published: November 2022

Background Pre-eclampsia is described as a pregnancy-specific syndrome that can affect virtually every organ system. The appearance of proteinuria remains an important diagnostic criterion. Proteinuria is an objective marker and reflects system-wide endothelial leak, which characterizes the pre-eclampsia syndrome.
Objective To determine protein values using the spot urinary albumin/creatinine ratio amongst the pregnant women and to identify whether this test can be used as the investigation of choice for predicting pre-eclampsia in near future.
Method A hospital based observational cross-sectional study conducted from February 2016 to August 2017. The study included pregnant women from 20-28 weeks of gestation. They were tested for spot urinary albumin and creatinine. They were all followed up till term, delivery and post partum.
Result The mean age of the study patients was 28 years (N+335), the most common age group being 25 to 29 years (43.6%). Pregnant women with higher values of urinary albumin/creatinine ratio were found to develop hypertension compared to women with normal values of urinary albumin/creatinine ratio in the third trimester with insignificant difference (p < 0.283) statistically.
Conclusion Microalbuminuria is one of the predictor of pre-eclampsia however it cannot be used as routine investigation for predicting pre-eclampsia in future; further studies in large scales are needed to prove whether urinary albumin/creatinine ratio can be utilized as predictor for pre-eclampsia or not.
Prescription Pattern Monitoring and Off-label Use of Medicines in the Pediatric Department at Tertiary Care Teaching Hospital
Authors: Pandey S. , Yadav C. K. , Ghimire P. , Shrestha A. C. 
Published: November 2022

Background Off-label use means the use, concerning dosage, indication, route of administration, or age, of pharmaceutical products which are beyond the terms of the product license. For regulatory bodies and physicians, the global challenge is to achieve optimum pediatric drug therapy.
Objective This prospective observational work was carried out in the paediatric department to evaluate the prescribing pattern of medicines and to identify the use of off-label drugs.
Method A cross-sectional study was carried in 200 paediatric patients of ages between 0 and 12 years at the paediatric outpatient department of Universal College of Medical Sciences, Bhairahawa. Data were collected by reviewing the prescription paper and the required information was recorded using a structured data collection sheet prepared for study. The prescribing pattern was assessed by using the World Health Organization (WHO) Prescription Indicators and off-label use was assessed using the WHO Children Formulary 2010.
Result Among 413 total prescriptions, only 5.56% of drugs were found to be prescribed by generic name, 16.7% of prescriptions were found to be antibiotic and 57.62% of prescribed drugs were from essential drug list. Out of 413 prescribed drugs, 16.46% of drugs were found to be off-label. The maximum extent of off-label prescribing was 51.47% in the child, followed by infants (42.6%) and neonates (5.8%). Fexofenadine; antihistaminic (23.56%), Amoxicillin+clavulanic acid; antibiotic (22.06%) had higher off-label use. Off-label dose (71.8%) was the most common cause of off-label prescribing.
Conclusion Off-label prescribing among pediatric patients is common. More eminence data on the safety and efficacy of off-label medicines must be generated to rationalize paediatric pharmacotherapy.
A Study on Variations of Branching Pattern of Hepatic Arteries with its Clinical Significance
Authors: Mansur D. I. , Karki S. , Shrestha A. , KC B. 
Published: November 2022

Background Variation of hepatic artery is very frequent and may predispose the patients to inadvertent injury to the vessels during hepato-billiary surgery. With the advancement of new diagnostic, therapeutic and operative techniques for abdomen, the sound knowledge of variations of hepatic arterial system have become increasingly important for dealing clinicians, surgeons and interventional radiologists.
Objective To study the variations of hepatic artery and to evaluate the possible clinical significances.
Method A total of 104 images of abdominal computed tomography scans were used for this study. The origin and branching patterns of hepatic artery were recorded. After collecting the data, statistical analysis was done.
Result The present study concluded that normal branching pattern of hepatic artery was seen in 86.54% cases, whereas 13.46% cases showed different types of variations. Among them, type II and IV pattern were seen in 0.96% in each, type VI in 1.93%, type VII in 2.87% and the most common variation type IX was seen in 3.85%. There were not a single case of type III, V, VIII and X recorded in this study. Addition to these, one of the variants was common hepatic artery originating from abdominal aorta, was seen in 1.93% of cases while the other variant is unnamed artery arising from superior mesenteric artery, was seen in 0.96% of cases.
Conclusion The knowledge of the branching pattern of hepatic artery might be helpful for clinicians to the better understanding of the arterial supply of the liver and may reduce the risk of complications.
Knowledge and Attitude Regarding Pubertal Changes among Secondary Level Students of Selected Schools of Dhulikhel Municipality
Authors: Shrestha S. , Neupane B. 
Published: November 2022

Background Adolescence is a transition phase of life during which a lot of pubertal changes occur. If not dealt properly, many mental and behavioral disturbances can result. Adolescents must have good knowledge and attitude regarding physical and psychosocial pubertal changes. Objective To assess the knowledge and attitude regarding pubertal changes among secondary level students of selected school of Dhulikhel Municipality.
Method A quantitative, descriptive cross-sectional study was conducted among secondary level students of Dhulikhel Municipality. Study was conducted among students of grade 9 and 10 of four government and three private schools of municipality. After selection of seven schools, proportionate stratified random sampling technique was done followed by lottery method to select required number of students. Both descriptive statistics and inferential statistics were applied using Statistical Package for Social Science (SPSS) Version 25.0 for data analysis.
Result The mean score of knowledge regarding pubertal changes was 26.2±2.9. Likewise, the mean attitude score regarding pubertal changes was 55.4±1.2. Knowledge regarding pubertal change was significantly higher among age group 15-17 years. Females had higher knowledge compared to males. Attitude related to pubertal change was significantly more in respondents who studied in government school.
Conclusion Adolescents of Dhulikhel municipality schools had good knowledge and attitude about pubertal changes.
Perception Regarding Care of Attempted Suicide Patients among Nursing Students in Kathmandu University School of Medical Sciences
Authors: Bajracharya J. , Bhandari N. , Chalise P. , Tiwari D. 
Published: November 2022

Background Suicide is an act of deliberately killing oneself. It is a global health problem and is the second leading cause of death in 15 to 29 years. Thus, studying nursing students’ perception towards suicide attempters has paramount importance in understanding and addressing the existing gaps in healthcare delivery system.
Objective To assess the nursing students’ perception towards attempted suicide and to find out the association between perception and selected variables.
Method A descriptive, cross sectional design was carried out to assess the nursing students’ perception towards suicide attempters in Kathmandu University School of Medical Sciences. The respondents were 193 nursing students. A structured questionnaire was used in order to collect data. Descriptive statistics including frequency, percentage, mean and standard deviation were calculated to summarize the data and inferential statistics, Mann Whitney-U test was used for the association between perception and selected variables.
Result A total 193 nursing students participated in this study. The scores between 1 and 2.4 were considered ‘positive’, ‘unsure’ or ‘uncertain’, between 2.5 and 3.4 and negative for 3.5 and above’ over all nurses showed relatively negative perception towards suicide attempters. According to results from eight domains of perception, those who did not attend the courses on psychiatry nursing presented higher score, which was found to have significant association with permissiveness, unpredictability and incomprehensibility. A younger nursing student shows significant association with incomprehensibility. Younger nursing student showed statistically significant association with duration of suicide process.
Conclusion Nursing students are frequently encountered with attempted suicide patients. Therefore, they must be aware of their attitudes toward this group of patients as part of their professional and therapeutic role. Thus a nurse’s positive perception towards attempted suicide can play a key role in communicating and preventing a future suicide attempt.
Prevalence and Associated Factors of Malnutrition in Under Five Children in a Rural Mountainous Area of Nepal: A Community Based Cross Sectional Study
Authors: Chataut J. , Jonchhe S. 
Published: November 2022

Background Nutrition is believed to be very essential for socio economic development of the country and is an essential component of sustainable development goals. Malnutrition is a major public health problem in Nepal and is more common among under-five year children. Malnutrition among children is complex problem globally, affecting the physical, mental and social development.
Objective To estimate the prevalence and explore the associated factors of malnutrition in study population.
Method It was a community based cross-sectional study conducted among rural population of Nepal. Wards were selected by simple random sampling technique and household in each ward were selected by systemic random sampling. The mothers of 302 participants aged 12 to 59 months were interviewed for requisite information using pretested questionnaire and anthropometric measurements were taken using standard technique for each participant. Statistical Package for Social Sciences (SPSS) version 16.0 was used for data analysis.
Result The prevalence of underweight, stunting and wasting was 36.8%, 37.5%, and 14.6% respectively. We found statistical significant association between underweight and children in lower age group, larger family size, lower level of mother’s education and illness in past one month. Factors that are significantly associated with stunting are children in lower age group, lower level of mother’s education and illness in past one month and wasting is significantly associated with children in lower age group.
Conclusion This study showed the prevalence of malnutrition is high in study population. Factors associated with malnutrition were child’s age, family size, mother’s education and illness in past one month.
Misleading Diagnosis of Dysgerminoma in a Young Asymptomatic Patient
Authors: Maharjan O. , Bajracharya N. , Dangal G. , Karki A. , Pradhan H. K. , Shrestha R. , Bhattachan K. , Tiwari K. , Bharati S. , Maharjan S. 
Published: November 2022

Dysgerminomas account for approximately one third of all malignant ovarian germ cell tumors (tumors arising from ovarian germinal elements) and are the most common ovarian malignancy detected during pregnancy. They are the only germ cell malignancy with a significant rate of bilateral ovarian involvement that is 15-20 percent. They have a variable gross appearance, but in general are solid, pink to tan to cream colored lobulated masses. They have the best prognosis of all malignant ovarian germ cell tumor variants. Two thirds are stage I at diagnosis, and prognosis is excellent even for those with advanced disease due to exquisite tumor chemosensitivity. The 5 year disease specific survival rate approximates 99 percent.
This is a case report of a huge ovarian dysgerminoma in a young unmarried lady that was quite asymptomatic. She underwent laparotomy with right ovarian cystectomy.
METHODOLOGICAL ASPECTS OF THE FORMATION OF PROFESSIONAL EXPERIENCE IN THE PREPARATION OF FUTURE SPECIALISTS IN ACTIVE TYPES OF TOURISM
Authors: Kollehaiev Mykhailo 
Published: November 2022

The article deals with the problems of training specialists for active types of tourism in the context of the formation of their professional experience. The forms and methods of formation and correction of situational formalization of professional experience in the world’s leading training systems are analyzed. In particular: the training of adventure tourism guides at the universities of Canada and New Zealand, as well as certified IFMGA / UIAGM / IVBV mountain guide training.The article analyzes the existing systems of sports and tourist, and mountaineering training, which were methodically developed and formed in the USSR. It is shown that these programs have limited effectiveness in terms of the situational diversity of experience formation at the stage of sports growth of tourists and climbers. At the same time, it is precisely the insufficient variety of situational design of experience that is the reason for the emergence of the “extreme situation” factor. It is shown that the negative impact of the “extreme situation” factor can manifest itself either in the form of erroneous actions that affect the safety or in the form of depletion of the body’s functional reserves or even damaging effects from excessive compensatory mechanisms of the adaptive response.The article analyzes the results of the implementation of preparation for complex combined trips in the Arctic, based on the author’s method of purposeful formation of a diverse situationally designed hiking experience.It is shown that the implemented author’s technique made it possible to exclude the occurrence of the “extreme situation” effect among the participants, despite the impact of strong and prolonged stress factors during difficult hikes.In addition, the applied methodology made it possible to avoid the shortcomings of the traditional system of training in hiking tourism and significantly reduce the time for the formation of universal high-class sportsmen-tourists by at least half.
Keywords: sports and tourism training; mountain guide; adventure tourism guide; professional experience; individual professional experience; situational design of experience; factor of “extreme situation”; category of difficulty; combined hike.
FEATURES OF THE ORGANIZATION OF LABORATORY WORKS IN THE STUDY OF PHYSICS BY STUDENTS OF IT SPECIALTIES
Authors: Varganova Dina , Kolomiiets Roman 
Published: November 2022

In this article, we analyze the problems of organizing laboratory work in physics for students of IT specialties in terms of distance learning. We show the possibility of convenient use of WEB technologies and JavaScript programming language for this purpose. The choice of JavaScript is due to the true platform-independence of this programming language: it is possible to write code in any text editor and run it in any web browser. Unlike specialized environments (Skratch), JavaScript is one of the most common languages of true programming, but the simplicity of syntax is also quite accessible to high school and first-year students. We give two examples: the first with deterministic motion (rectilinear uniform and accelerated) and the second with chaotic motion (Brownian motion). The article describes the structure of a typical mini-project (laboratory work) and shows that this approach in the organization of training is related to the specifics of the IT specialty. Now we consider only “static” cases – that is, without the use of animation. However, JavaScript tools also allow you to implement “dynamics”, i.e. with animation. According to such a scheme, it is possible to implement almost any of the known physical processes. As a result, students acquire skills in programming models of physical processes with visual visualization of the results. Such models make it possible to change the initial conditions for the development of the physical process and see the process of its course, to compare the program-experimental results with the calculated, deeper and more complete understanding of the physical process during its programming. Thus, the foundation of knowledge of the future engineer – CAD designer (computer-aided design systems, which are widely used in real production and especially in its preparation).
Keywords: educational technologies of distance learning; modeling of motion processes in physics; modeling of Brownian motion; development of simulators of physical processes; JavaScript; WEB technologies in education; laboratory works in physics; virtual learning environment.
PSYCHOLOGICAL AND PEDAGOGICAL SUPPORT FOR THE INDIVIDUAL-CREATIVE PROFESSIONAL FORMATION OF FUTURE FOOD INDUSTRY ENGINEERING TEACHERS
Authors: Kurilo Olga 
Published: November 2022

The article presents theoretical aspects of psychological and pedagogical support for the individual-creative professional formation of future engineers in the industry of food.According to the purpose, the following tasks of the study are defined: to investigate the features of psychological and pedagogical support in the educational process; to disclose the content of psychological and pedagogical support of future food industry engineers-teachers; to identify the expected results of the individual-creative professional formation of future food industry engineering teachers.To achieve the goal and solve the defined tasks a set of interrelated theoretical research methods was used. They are the analysis of psychological and pedagogical literature and scientific research on the problem of psychological and pedagogical support (to identify the features of psychological and pedagogical support in the educational process), generalization and systematization (to predict the expected results of the individual-creative professional formation of future food industry engineering teachers).It is determined that psychological and pedagogical support contributes to the activation of higher education applicants and the formation of their desire for professional growth, taking into account the acquired knowledge about themselves, their abilities and prospects of their development. The organization of psychological and pedagogical support accelerates the processes of disclosure and realization of the personal potential of future food industry engineering teachers in the professional formation process at the stage of study at the institution of higher education.
Keywords: psychological and pedagogical support; individual-creative professional formation; engineering teacher; food industry; individual training program; personal experience; potential opportunities; readiness for creative professional activity.