bluuebunny/crossref_metadata_2025_split huggingface dataset:
Necklace‐Like Nanostructures: From Fabrication, Properties to Applications
Authors: Zhang Lei , Biesold Gill M. , Zhao Chunyan , Xu Hui , Lin Zhiqun 
Published: June 2022

AbstractThe shape‐controlled synthesis of nanocrystals remains a hot research topic in nanotechnology. Particularly, the fabrication of 1D structures such as wires, rods, belts, and tubes has been an interesting and important subject within nanoscience in the last few decades. 1D necklace‐like micro/nanostructures are a sophisticated geometry that has attracted increasing attention due to their anisotropic and periodic structure, intrinsic high surface area, abundant transport channels, exposure of each component to the surface, and multiscale roughness of the surface. These characteristics enable their unique electrical, optical, and catalytic properties. This review provides a comprehensive summary of the advanced research progress on the fabrication strategies, novel properties, and various applications of necklace‐like structures. It begins with the main fabrication methods of necklace‐like structures and subsequently details a variety of their properties and applications. It concludes with the authors’ perspectives on future research and development of the necklace‐like structures.
Interfacial Exchange Phenomena Driven by Ferromagnetic Domains
Authors: Díez José Manuel , Cuñado José Luis F. , Lapa Pavel , Solís Raúl , Arnay Icíar , Pedraz Patricia , Perna Paolo , Bollero Alberto , Miranda Rodolfo , Schuller Ivan K. , Camarero Julio 
Published: June 2022

AbstractInterfacial proximity effects in antiferromagnetic/ferromagnetic (AFM/FM) bilayers control the exchange‐bias (EB) phenomena exploited in most spintronic devices, although still is lack of full understanding. Discordant results, including different exchange‐bias field (HE), coercivity (HC), or blocking temperature (TB) found even in similar systems, are usually ascribed to uncontrolled parameters, namely dissimilar interfacial defects, structure, and thicknesses. Here, it is shown in the very same sample that the magnetic domain structure during the magnetization reversal of the FM layer controls those mentioned effects. Simultaneous transport and vectorial‐resolved magnetic measurements performed in a V2O3/Co system during warming after different field cooling (FC) procedures exhibit a strong dependence on the FC angle and the domain structure of the FM layer. Remarkably, magnetization reversal analysis reveals 35 K of variation in TB and up to a factor of two in HE. These observations can be explained within the random‐field model for the interfacial exchange coupling with a fixed AFM domain structure in contact with a variable (angle‐dependent) FM domain structure. The results highlight the importance of the domain structure and magnetization reversal of the FM layer (not previously considered) in the EB phenomena, with potential to tailor interfacial effects in future spintronic devices.
Tumor‐Activatable Nanoparticles Target Low‐Density Lipoprotein Receptor to Enhance Drug Delivery and Antitumor Efficacy
Authors: Jiang Xiaomin , Han Wenbo , Liu Jianqiao , Mao Jianming , Lee Morten J. , Rodriguez Megan , Li Youyou , Luo Taokun , Xu Ziwan , Yang Kaiting , Bissonnette Marc , Weichselbaum Ralph R. , Lin Wenbin 
Published: June 2022

AbstractThe binding of plasma proteins to nanomedicines is widely considered detrimental to their delivery to tumors. Here, the design of OxPt/SN38 nanoparticle containing a hydrophilic oxaliplatin (OxPt) prodrug in a coordination polymer core and a hydrophobic cholesterol‐conjugated SN38 prodrug on the lipid shell for active tumor targeting is reported. OxPt/SN38 hitchhikes on low‐density lipoprotein (LDL) particles, concentrates in tumors via LDL receptor‐mediated endocytosis, and selectively releases SN38 and OxPt in acidic, esterase‐rich, and reducing tumor microenvironments, leading to 6.0‐ and 4.9‐times higher accumulations in tumors over free drugs. By simultaneously crosslinking DNA and inhibiting topoisomerase I, OxPt/SN38 achieved 92–98% tumor growth inhibition in five colorectal cancer tumor models and prolonged mouse survival by 58–80 days compared to free drug controls in three human colorectal cancer tumor models without causing serious side effects. The study has uncovered a novel nanomedicine strategy to co‐deliver combination chemotherapies to tumors via active targeting of the LDL receptor.
Humidity‐Enabled Organic Artificial Synaptic Devices with Ultrahigh Moisture Resistivity
Authors: Li Jiayu , Qian Yangzhou , Li Wen , Lin Yen‐Hung , Qian Haowen , Zhang Tao , Sun Ke , Wang Jin , Zhou Jia , Chen Ye , Zhu Jintao , Zhang Guangwei , Yi Mingdong , Huang Wei 
Published: June 2022

AbstractOrganic memristors with homogeneous resistive switching behaviors can emulate the functionalities of biological synapses, making them promising candidates for use in brain‐inspired neuromorphic computing. Among various environmental parameters, humidity affecting device operational stability is a critical issue that organic memristors face in practical applications. A high humidity resistant organic memristor is demonstrated here using a small molecule material F16CuPc. Unencapsulated devices show excellent moisture stability, maintaining reliable memristive switching behavior after 1 year of exposure to air at 60% high relative humidity and remaining operational when immersed in water for 96 h. A proton conduction mechanism is discovered responsible for the resistive switching effect. The continuously adjustable conductance in F16CuPc‐based memristive devices enables the mimicking of biological synapse functions. These results open up a path to a humidity tolerant neuromorphic computing system based on high humidity resistant artificial synapse devices.
Comprehensive reaction kinetics model of CO2 absorption into 1‐dimethylamino‐2‐propanol solution
Authors: Liu Helei , Jiang Xiaotong , Idem Raphael , Dong Shoulong , Tontiwachwuthikul Paitoon 
Published: June 2022

AbstractIn the present work, the kinetics of the reactive absorption of CO2 in 1‐dimethylamino‐2‐propanol (1DMA2P) solution were experimentally measured using a laminar jet absorber over a temperature range of 298–313 K, 1DMA2P concentration range of 0.5–2.0 mol/L, and CO2 loading range of 0–0.06 mol CO2/mol amine. The measured kinetics data were then used to develop a comprehensive numerical kinetics model using a FEM‐based COMSOL software. The reaction rate model of the CO2 absorption into 1DMA2P solution were then validated by comparing model rates with the experimental rates. An excellent agreement of model data with experimental data was achieved with an absolute average deviation (AAD) of 6.5%. In addition, vapor–liquid equilibrium plots of all ions in the 1DMA2P‐H2O‐CO2 system were also developed. Further, this work has provided an effective criterion for evaluating CO2 absorption, that can be used for both the conventional amines and alternative amines for the purpose of providing guidelines or information on how to effectively screen solvents.
Rh(III)‐Catalyzed C6‐Selective C−H 3‐Oxoalkylation of 2‐Pyridones with Allylic Alcohols
Authors: Shan Yujia , Huang Gao , Yu Jin‐Tao , Pan Changduo 
Published: June 2022

AbstractRhodium(III)‐catalyzed C6‐selective C−H 3‐oxoalkylation of 2‐pyridones was developed with commercially available allylic alcohols as the 3‐oxoalkyl sources. In this reaction, the excellent site selectivity was controlled by the 2‐pyridyl directing group on the nitrogen of the pyridone ring. This reaction features good functional group tolerance and the generation of 6‐(3‐oxoalkyl) pyridones in moderate to good yields.
Combined superposition effect of hypertension and dyslipidemia on left ventricular hypertrophy
Authors: Zhang Xueyao , Li Guangxiao , Shi Chuning , Zhang Dongyuan , Sun Yingxian 
Published: June 2022

AbstractBackgroundHypertension and dyslipidemia are considered reversible risk factors for cardiovascular disease. The purpose of this study was to explore the impact of traditional and nontraditional blood lipid profiles on the risk of left ventricular hypertrophy (LVH) and to explore the superposition effect of dyslipidemia combined with hypertension.MethodsData on 9134 participants (53.5 ± 10.3 years old) from the Northeast China Rural Cardiovascular Health Study (NCRCHS) were statistically analyzed. The blood lipid profile was measured by total cholesterol (TC), low‐density lipoprotein cholesterol (LDL‐C), high‐density lipoprotein cholesterol (HDL‐C), total glyceride (TG), and calculated nontraditional blood lipid indices including non‐HDL‐C, atherosclerosis index (AI), TC/HDL‐C, and residual cholesterol (RC).ResultsAfter the adjustment of age and gender, the odds ratios (ORs) of LVH in patients with hypertension, high LDL‐C, high non‐HDL‐C, high AI, and high TC/HDL‐C were 3.97 (3.31–4.76), 1.27 (1.02–1.59), 1.21 (1.04–1.39), 1.33 (1.15–1.53), and 1.42 (1.22–1.65), respectively. After full adjustment of potential confounding factors, high AI and TC/HDL‐C were associated with LVH rather than traditional blood lipid indices. The combination of hypertension and nontraditional dyslipidemia (defined by high AI and TC/HDL‐C) was associated with the highest risk of LVH, especially in participants under 45 years of age. The risk was more significant in men, 5.09‐fold and 6.24‐fold, respectively, compared with 3.66‐fold and 4.01‐fold in women.ConclusionsPeople with dyslipidemia defined by nontraditional blood lipid indices (high AI and high TC/HDL‐C) and hypertension were more likely to develop LVH.
Mouse Cyp2c expression and zonation structure in the liver begins in the early neonatal stage
Authors: Kawamura Taisuke , Ichikawa Mako , Hatogai Jo , Koyama Yuya , Tachibana Misa , Kuwahara Misaki , Negishi Keita , Matsumoto Miyu , Miyazaki Masafumi , Ochiai Wataru 
Published: June 2022

AbstractIn the adult liver, drug‐metabolizing enzymes such as cytochrome P450 (CYP) efficiently metabolize drugs by forming an expression pattern called “zonation” structure around the central veins (CV). However, most previous studies on CYPs have focused on the expression levels of CYP mRNA and proteins in the whole liver. In this study, we analyzed not only the expression levels of Cyp2c family mRNAs and proteins in mice during fetal liver development, but also the relationship with their localization. In the whole fetal liver, Cyp2c mRNA and protein were hardly expressed. On the other hand, zonation analysis results showed that only some cells around the CV of the fetal liver expressed Cyp2c. In addition, the protein expression level of Cyp2c in the whole liver during the neonatal period started from postnatal day (P) 7 in both males and females, while the zonation was weakly formed from P5. This study suggested that fetal liver cannot metabolize Cyp2c substrate drugs transferred from mother to fetus due to the low expression of Cyp2c and unformed zonation. The expression level of Cyp2c protein in neonates was lower than that in adult liver, and the zonation structure was not clear, suggesting that drug metabolism was not sufficient. Furthermore, this study revealed that the expression level of Cyp2c does not correlate with the formation of zonation structures, because Cyp2c expression is found in hepatocytes near the CV even in the fetal and neonatal stages, when Cyp2c protein expression is hardly detectable in the whole liver.
13,13′‐Diphenalkyl β‐carotenes as pi‐stacking models of chlorophylls and carotenoids in photosynthesis
Authors: Lim Boram , Kim Young‐Hun , Kim Hyein , Park Myeongnam , Yeo Huisu , Koo Sangho 
Published: June 2022

Abstract2,7‐Diphenalkyl‐4‐octenedials 3 were prepared for the syntheses of 13,13′‐diphenalkyl β‐carotenes 1b–1d, which serve as the intramolecular models for the π‐stacking interactions of chlorophylls and carotenoids. The optimal tether length of the 13‐phenalkyl substituents in carotenes 1b–1d for the maximum π–π interactions with the polyene chain was decided to be a three‐methylene unit based on the most up‐field chemical shifts of the nearby protons of H11 and H15 by the magnetic anisotropic effect of benzene rings, which would provide a valuable information in the assembly of a single molecular light‐harvesting/energy‐transferring unit for artificial photosynthetic system.
Is ESG mutual fund quality in the eye of the beholder? An experimental study of investor responses to ESG fund strategies
Authors: Carlsson Hauff Jeanette , Nilsson Jonas 
Published: June 2022

AbstractESG‐profiled mutual funds (funds incorporating some form of Environmental, Social, or Governance‐related concern) is an increasingly prominent part of the financial services industry. While this category of funds may look homogenous on the surface, the fact is that there is there is considerable variation in how funds choose to account for ESG concern in the investment portfolio. In this paper, we ask whether these strategic choices surrounding the implementation of ESG affect retail investors' perception of sustainable quality, financial quality, and/or perceived overall quality of the ESG‐fund. Through two experiments (n = 261; n = 437), we find that choice of ESG‐strategy (exclusion, inclusion, or engagement) impacts perceived mutual fund quality, with a marked preference for the inclusion strategy. Surprisingly, however, we find that the impact on overall fund quality is mediated by perceived financial quality, not perceived sustainable quality. In a similar fashion, we also find that implementing the strategy through in‐house sustainability experts, as opposed to relying on external sustainability expertise, positively affect perceived quality, through perceived financial quality. In all, these results highlight that the manner in which ESG‐factors are integrated in the investment portfolio can affect perceived quality of mutual funds, as investors consciously or unconsciously assign different financial expectations to the strategies.
A Highly Stable Bimetallic Transition Metal Phosphide Catalyst for Selective Dehydrogenation of n‐Heptane
Authors: Stöber Robert , Mai Florian , Sebastian Oshin , Körner Andreas , Hutzler Andreas , Schühle Patrick 
Published: June 2022

AbstractIn this work, we demonstrate RuP2‐MoP catalysts being highly stable and selective for the dehydrogenation of long‐chain alkanes like n‐heptane. Compared to a monometallic MoP catalyst, the bimetallic system substantially increases n‐heptene selectivity from 40 % towards 80 %. This effect can be traced back to a reduced surface acidity, suppressing the competitive hydrogenolysis reaction. The active transition metal phosphide is, furthermore, compared to its phosphorous‐free RuMo‐counterpart. As revealed by STEM‐EDX investigations, incorporation of phosphorous results in the formation of separated metal phosphide clusters instead of an intermetallic alloy. In the dehydrogenation of n‐heptane the phosphorous modification clearly avoids catalyst deactivation and maintains the high n‐heptene selectivity. X‐ray diffraction, elemental analysis and STEM‐EDX further reveal that catalyst coking and the formation of less active molybdenum carbide phases is effectively suppressed by phosphorous incorporation, making RuP2‐MoP an attractive system for selective dehydrogenation of long‐chain alkanes.
Levulinic Acid Hydrogenation with Homogeneous Cu(I) Catalyst
Authors: Jurado‐Vázquez Tamara , Rosaldo Efrén , Arévalo Alma , García Juventino J. 
Published: June 2022

AbstractWe report the first well‐defined homogeneous copper‐based catalyst for levulinic acid (LVA) hydrogenation using complex [(PPh3)2Cu(k2‐O,O‐LVA)] as a copper source and (1,2‐bis(diisopropyl phosphino)ethane (dippe) as an ancillary ligand. This catalytic precursor has high activity in LVA hydrogenation and yields γ‐valerolactone (GVL) under relatively mild reaction conditions (24 h, 140 °C) in a base‐free system using H2 (300 psi) as a reductant. Under optimized conditions, GVL was obtained with excellent yield (>99 %) and selectivity (>99 %) using a low catalytic load (0.025 mol %), allowing a TON=4000.
Chondroid syringoma of the axilla: A potential for misdiagnosis as metastatic carcinoma on fine needle aspiration cytology
Authors: Kim Nah Ihm , Lim Hyo Soon , Lee Ji Shin 
Published: June 2022

AbstractChondroid syringoma is a rare benign adnexal tumor and tends to occur in the head and neck region. Involvement in the axilla is very unusual, and the differential diagnosis of such presentations includes lymphadenopathy and cyst. Fine needle aspiration cytology (FNAC) is a very useful tool for the diagnosis of chondroid syringoma. The characteristic feature of chondroid syringoma in cytology is the presence of distinct biphasic cell populations of epithelial and myoepithelial cells in the chondromyxoid stroma. If the typical biphasic cellular and chondromyxoid stromal elements are not visible in smears, it may be misdiagnosed in cytology. Here, we describe a case of axillary chondroid syringoma that was initially misdiagnosed as a metastatic carcinoma by FNAC. Although chondroid syringoma rarely occurs in the axilla, it should be included among the differential diagnoses of an axillary mass. Cytopathologists need to discern the unique cytological features of chondroid syringoma and avoid misdiagnosis for prompt management of the patient.
Condition dependence in biosynthesized chemical defenses of an aposematic and mimetic Heliconius butterfly
Authors: Mattila Anniina L. K. , Jiggins Chris D. , Saastamoinen Marjo 
Published: June 2022

AbstractAposematic animals advertise their toxicity or unpalatability with bright warning coloration. However, acquiring and maintaining chemical defenses can be energetically costly, and consequent associations with other important traits could shape chemical defense evolution. Here, we have tested whether chemical defenses are involved in energetic trade‐offs with other traits, or whether the levels of chemical defenses are condition dependent, by studying associations between biosynthesized cyanogenic toxicity and a suite of key life‐history and fitness traits in a Heliconius butterfly under a controlled laboratory setting. Heliconius butterflies are well known for the diversity of their warning color patterns and widespread mimicry and can both sequester the cyanogenic glucosides of their Passiflora host plants and biosynthesize these toxins de novo. We find energetically costly life‐history traits to be either unassociated or to show a general positive association with biosynthesized cyanogenic toxicity. More toxic individuals developed faster and had higher mass as adults and a tendency for increased lifespan and fecundity. These results thus indicate that toxicity level of adult butterflies may be dependent on individual condition, influenced by genetic background or earlier conditions, with maternal effects as one strong candidate mechanism. Additionally, toxicity was higher in older individuals, consistent with previous studies indicating accumulation of toxins with age. As toxicity level at death was independent of lifespan, cyanogenic glucoside compounds may have been recycled to release resources relevant for longevity in these long‐living butterflies. Understanding the origins and maintenance of variation in defenses is necessary in building a more complete picture of factors shaping the evolution of aposematic and mimetic systems.
Research on the mixed control strategy of the battery energy storage considering frequency modulation, peak regulation, and SOC
Authors: Liu Shuo , Zhao Lining , Huang Senyu , You Honghao , Li Jianlin , Yang Liyong 
Published: June 2022

AbstractThe battery energy storage system (BESS) is considered as an effective way to solve the lack of power and frequency fluctuation caused by the uncertainty and the imbalance of renewable energy. Based on these, this paper proposes a mixed control strategy for the BESS. First, this paper divides the demand for frequency modulation, peak regulation, and state of charge (SOC) of the battery into different zones. Then the Kuramoto model modulates the frequency, and the self‐recovery strategy is used to optimize the SOC. Meanwhile, the proposed mixed control strategy is used to integrate frequency control, demand control, and SOC optimization. Finally, the simulation results verify the rationality of the strategy.
Hepatitis C is associated with more adverse pregnancy outcomes than hepatitis B: A 7‐year national inpatient sample study
Authors: Chen Bing , Wang Yichen , Lange Marcia , Kushner Tatyana 
Published: June 2022

Abstract
Prior international studies have shown mixed results regarding the association of hepatitis B and hepatitis C with adverse pregnancy outcomes. We performed an updated evaluation of the prevalence of associated adverse pregnancy outcomes and evaluated trends over time of diagnosis of chronic hepatitis B (HBV) and chronic hepatitis C (HCV) in pregnant women in a national database. All pregnant women with HBV and HCV were identified from the National Inpatient Sample database 2012 to 2018. Multivariate logistic regression analyses were performed to compare pregnancy‐related complications, including rates of preeclampsia/eclampsia, gestational diabetes, intrauterine growth restriction, antepartum/intrapartum hemorrhage, preterm labor, and Cesarean section. We evaluated all‐cause in‐hospital mortality, length of stay, and total cost of hospitalizations. A total of 28.7 million pregnancy‐related hospitalizations that met our eligibility criteria were identified, including 51,200 with HBV and 131,695 with HCV. In comparison with the uninfected controls, the HBV group was significantly more likely to develop gestational diabetes (12.94% vs. 6.94%, p < 0.001). The HCV group was more likely to have preterm labor (9.63% vs. 6.27%, p < 0.001), intrauterine growth restriction (6.04% vs. 2.89%, p < 0.001), longer length of stay (3.4 days vs. 2.7 days, p < 0.001), and higher hospitalization cost (15,052 dollars vs. 14,258 dollars, p < 0.001). These findings should inform counseling of women who are found to have HBV or HCV during pregnancy regarding the risk of adverse pregnancy outcomes and support the need for an interdisciplinary approach to optimize maternal and neonatal outcomes.