bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uptake of Sotrovimab for prevention of severe COVID-19 and its safety in the community in England
Authors: Patone Martina , Snelling Andrew JHL , Tibble Holly , Coupland Carol AC , Sheikh Aziz , Hippisley-Cox Julia 
Published: August 2022

ABSTRACTSotrovimab is a neutralising monoclonal antibody (nMAB), currently administrated in England to treat extremely clinically vulnerable COVID-19 patients. Trials have shown it to have mild or moderate side effects, however safety in real-world settings has not been yet evaluated. We used national databases to investigate its uptake and safety in community patients across England. We used a cohort study to describe uptake and a self-controlled case series design to evaluate the risks of 49 pre-specified suspected adverse events in the 2-28 days post-treatment. Between December 11, 2021 and May 24, 2022, there were 172,860 COVID-19 patients eligible for treatment. Of the 22,815 people who received Sotrovimab, 21,487 (94.2%) had a positive SARS-CoV-2 test and 5,999 (26.3%) were not on the eligible list. Between treated and untreated eligible individuals, the mean age (54.6, SD: 16.1 vs 54.1, SD: 18.3) and sex distribution (women: 60.9% vs 58.1%; men: 38.9% vs 41.1%) were similar. There were marked variations in uptake between ethnic groups, which was higher amongst Indian (15.0%; 95%CI 13.8, 16.3), Other Asian (13.7%; 95%CI 11.9, 15.8), White (13.4%; 95%CI 13.3, 13.6), and Bangladeshi (11.4%; 95%CI 8.8, 14.6); and lower amongst Black Caribbean individuals (6.4%; 95%CI 5.4, 7.5) and Black Africans (4.7%; 95%CI 4.1, 5.4). We found no increased risk of any of the suspected adverse events in the overall period of 2-28 days post-treatment, but an increased risk of rheumatoid arthritis (IRR 3.08, 95% CI 1.44, 6.58) and of systematic lupus erythematosus (IRR 5.15, 95% CI 1.60, 16.60) in the 2-3 days post-treatment, when we narrowed the risk period.FundingNational Institute of Health Research (Grant reference 135561)
An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors
Authors: Singh Raminder , Rossini Valerio , Stockdale Stephen R. , Saiz-Gonzalo Gonzalo , Hanrahan Naomi , D’ Souza Tanya , Clooney Adam , Draper Lorraine A. , Hill Colin , Nally Ken , Shanahan Fergus , Andersson-Engels Stefan , Melgar Silvia 
Published: August 2022

ABSTRACTConflicting evidence exists on the association between consumption of non-steroidal anti-inflammatory drugs (NSAIDs) and symptomatic worsening of inflammatory bowel disease (IBD). We hypothesise that the heterogeneous prevalence of pathobionts [e.g., adherent-invasiveEscherichiacoli (AIEC)], might explain this inconsistent NSAIDs/IBD correlation. UsingIL10-/-mice, we show aggravation of colitis in AIEC-colonised animals fed NSAID. This is accompanied by activation of the NLRP3 inflammasome, Caspase-8, apoptosis and pyroptosis; features not seen in mice exposed to AIEC or NSAID alone, revealing an AIEC/NSAID synergistic effect. Inhibition of NLRP3 or Caspase-8 activity ameliorated colitis, with reduction in NLRP3 inflammasome activation, cell death markers and activated T-cells and macrophages, improved histology and increased abundance ofClostridiumcluster XIVa species. Our findings provide mechanistic insights into how NSAID and an opportunistic gut-pathobiont can synergise to worsen IBD symptoms. Thus, targeting the NLRP3 inflammasome and Caspase-8 could be a potential therapeutic strategy in patients with NSAID-worsened inflammation.
Distinct roles of forward and backward alpha-band waves in spatial visual attention
Authors: Alamia Andrea , Terral Lucie , D’ambra Malo Renaud , VanRullen Rufin 
Published: August 2022

AbstractPrevious research has associated alpha-band [8-12Hz] oscillations with inhibitory functions (Klimesch et al., 2007; Jensen and Mazaheri, 2010): for instance, several studies showed that visual attention increases alpha-band power in the hemisphere ipsilateral to the attended location (Thut et al., 2006; Händel et al., 2011). However, other studies demonstrated that alpha oscillations positively correlate with visual perception (Busch et al., 2009; Vanrullen and MacDonald, 2012), hinting at different processes underlying their dynamics. Here, using an approach based on traveling waves, we demonstrate that there are two functionally distinct alpha-band oscillations propagating in different directions. We analyzed EEG recordings from two datasets of human participants (N=32, both genders) performing a covert visual attention task. Participants were instructed to detect a brief target by covertly attending to the screen’s left or right side. Our analysis reveals two distinct processes: allocating attention to one hemifield increases top-down alpha-band waves propagating from frontal to occipital regions ipsilateral to the attended location, both with or without visual stimulation. These top-down oscillatory waves correlate positively with alpha-band power in frontal and occipital regions. Yet, different alpha-band waves propagate from occipital to frontal regions and contralateral to the attended location. Crucially, these forward waves were present only during visual stimulation, suggesting a separate mechanism related to visual processing. Together, these results reveal two distinct processes reflected by different propagation directions, demonstrating the importance of considering oscillations as traveling waves when characterizing their functional role.
Evaluation of the performance of the multi-objective scalarization methods for the aircraft sequencing and scheduling problem using multi-criteria decision-making
Authors: Dönmez Kadir 
Published: August 2022

Purpose
This study aims to evaluate the performance of the most popular multi-objective programming scalarization methods in the literature for the aircraft sequencing and scheduling problem (ASSP). These methods are the weighted sum method, weighted goal programming, the ε-constraint method, the elastic constraint method, weighted Tchebycheff and augmented weighted Tchebycheff.

Design/methodology/approach
First, the ASSP for a single runway case was modeled using mixed-integer programming considering the safety and operational constraints and the objectives of the minimization of total delay and total flight time for a sample airport. The objectives were then combined by using the multi-objective programming scalarization methods and various expected times of arrival–departure samples were run for the mathematical models. Finally, the methods were evaluated in terms of the number of nondominated solutions, superior nondominated solution and the average solution time using the Measurement of Alternatives and Ranking according to Compromise Solution method, which is a popular multi-criteria decision-making method.

Findings
Augmented Weighted Tchebycheff was found to be the most effective approach to ASSP in terms of the evaluation criteria followed by Weighted Tchebycheff and then weighted sum method.

Practical implications
The methodology presented in this study could provide more efficient air traffic management in terminal maneuvering areas when multiple objectives need to be optimized.

Originality/value
Although there are studies including the comparison of several scalarization methods for other problems, the comparison of the methods for ASSP has not yet been handled in the literature. As there are several stakeholders in the air traffic system, ASSP includes several objectives, and as a result, this problem can benefit from analyses using this comparison.
Reducing perseverative requesting and other problem behavior in a young girl with autism: a sequentially implemented intervention package
Authors: Chen Mo , Kreibich Shelley 
Published: August 2022

Purpose
This study aims to use a sequentially implemented intervention package to reduce the occurrence of perseverative requesting and other problem behavior in a young girl with autism spectrum disorder (ASD).

Design/methodology/approach
In this single-case study, subsequent to a functional analysis and a preference assessment, an intervention package consisting of three components (i.e. a tolerance for delay to reinforcement, choice-making and visual schedule) was implemented sequentially to address perseverative requesting and other problem behavior maintained by access to preferred items/activities in a young girl with ASD.

Findings
Via the intervention package, the girl demonstrated higher self-control skills (i.e. delaying access to preferred items/activities, choosing more preferred items/activities with delayed access over less preferred ones with immediate access, completing tasks before having access to preferred items/activities) with a reduction of perseverative requesting or other problem behavior.

Originality/value
The current case study presents concrete steps that could be applied to address tangible-maintained perseverative requesting using more natural and educationally relevant signals while improving the child’s appropriate skills (e.g. delay to reinforcement, self-control and task engagement).
Drivers for SMEs participation in entrepreneurial ecosystems: evidence from health tech ecosystem in Northern Finland
Authors: Mohammadparast Tabas Abdollah , Kansheba Jonathan Mukiza Peter , Komulainen Hanna 
Published: August 2022

PurposeThe entrepreneurial ecosystem (EE) literature is dominated by conceptual studies with insufficient theoretical foundations and empirical evidence on the micro-level. This study aims to explore the largely overlooked question of what the drivers that motivate small and medium-sized enterprises (SMEs) to participate in an ecosystem are.Design/methodology/approachThe study adopts a qualitative exploratory approach. The empirical data consists of 19 semi-structured interviews with top management of SMEs in the health tech ecosystem in Finland. The data were analyzed using a thematic content analysis.FindingsThis study reveals a typology of drivers that motivate SMEs to participate in an ecosystem. These include social drivers (networking and cooperation and communication and knowledge sharing), resource drivers (access to resources, formal and informal support and market access) and cognitive drivers (shared goals and common values).Research limitations/implicationsThe study contributes to the EE research by highlighting the drivers that motivate health tech SMEs to become members of the local ecosystem. It suggests that managers and entrepreneurs need to be aware of the factors related to social, resource and cognitive drivers to ensure the future success of their business.Originality/valueThe study draws evidence from a micro-level perspective which enriches the understanding of the EE phenomenon. It also explores an increasingly relevant but under-researched field, the health tech ecosystem.
Foreign ownership and liquidity: evidence from a frontier market
Authors: Bousnina Amina , Gana Marjène Rabah , Dakhlaoui Mejda 
Published: August 2022

PurposeThis study aims to provide empirical evidence on the impact of foreign share ownership on the liquidity of the Tunisian Stock Exchange (TSE).Design/methodology/approachThe authors hypothesize in the first strand that stock liquidity could be positively affected by foreign ownership based on the real friction channel. The authors then hypothesize in the second strand, based on the information friction channel, that foreign ownership's impact on stock liquidity could be insignificant or negative and that foreign investors raise the level of information asymmetry. A sample of 318 firm-year observations from Tunisia over the 2012–2017 period and a random-effects estimation were used. Moreover, using the 2SLS estimator, a robustness check framework was applied in order to address any potential reverse causality concerns.FindingsThe authors find strong evidence that higher foreign ownership improves stock liquidity. More specifically, firms with higher foreign ownership engender a lower bid-ask spread, a better stock ability to absorb a large amount of trading volume, and a larger depth. These findings are still valid when reverse causality concerns are addressed through the use of the 2SLS estimator.Originality/valueThe paper contributes to the existing literature by focusing on the ownership–liquidity relationship on a frontier market. It provides further empirical support that higher corporate governance quality reduces the information asymmetry problem and enhances stock market liquidity.
Magneto-radiative gas near an unsmooth boundary with variable temperature
Authors: He Ji-Huan , Elgazery Nasser S. , Abd Elazem Nader Y. 
Published: August 2022

Purpose
This paper aims to study the magneto-radiative gas (water vapor) on an unsmooth boundary.

Design/methodology/approach
This paper provided a numerical treatment via the implicit Chebyshev pseudo-spectral method to investigate unsteady compressible magneto-radiative gas (water vapor Pr = 1) flow near a heated vertical wavy wall through porous medium in the presence of inclined magnetic field. The impacts of viscous dissipation, temperature-dependent fluid properties, thermal conductivity and viscosity in the presence of nonlinear thermal radiation are studied. The sinusoidal surface is transformed into a flat one using a suitable transformation. The comparison figures of published data with the present outcomes illustrate a good match. The present steady-state outcomes are presented for the temperature, velocity, Nusselt number and the shearing stress through figures for several interested physical parameters, namely, compressibility, magnetic, radiation, viscosity–temperature variation, thermal conductivity–temperature variation, surface sinusoidal waveform and porous parameters.

Findings
The present numerical outcomes confirm the importance of applying nonlinear thermal radiation cases in all studies that investigate heat transfer under the influence of thermal radiation.

Originality/value
A mathematical model is established for a wavy boundary, and Chebyshev pseudo-spectral method is adopted for the numerical study.
Does practicing spirituality at workplace make teachers more engaged? Examining the role of emotional intelligence
Authors: Pradhan Rabindra Kumar , Jandu Kailash , Samal Jayalaxmi , Patnaik Janaki Ballav 
Published: August 2022

Purpose
Drawing on the positive activity model, this study aims to investigate the impact of workplace spirituality on the level of engagement shown by the teachers at higher education institutions. This study also tries to explore if emotional intelligence acts as a mediator in the relationship between workplace spirituality and employee engagement.

Design/methodology/approach
Using the purposive sampling technique, data were collected from the teachers (N = 287) teaching at various Indian educational institutions imparting tertiary education. The variables under study were measured using standardized instruments. The data were analyzed by means of Statistical Package for Social Sciences 20.0 and Analysis of Moment Structures software tools.

Findings
The findings generated from structural equation modeling analysis revealed that the teachers who practiced spirituality at their workplace were more engaged. Furthermore, emotional intelligence partially mediated this relationship.

Practical implications
This study underscores the importance of providing a spiritually conducive work milieu and nurturing emotional intelligence among the higher education teachers for better job outcomes.

Originality/value
This study offers insights into the mechanism linking spirituality at the workplace (a positive activity) and employee engagement (an indicator of well-being) in the context of higher education sector.
A meta-analysis of the factors associated with s-commerce intention: Hofstede's cultural dimensions as moderators
Authors: Jadil Yassine , Jeyaraj Anand , Dwivedi Yogesh K. , Rana Nripendra P. , Sarker Prianka 
Published: August 2022

PurposeIn recent years, the proliferation of social commerce (s-commerce) has attracted many researchers to investigate the drivers of individuals' intentions. However, the empirical results reported in these studies were fragmented and inconsistent. This has led various meta-analyses to synthesize these findings, but without including a large number of s-commerce studies. In addition, investigating meta-analytically the effects of moderators such as the six dimensions of Hofstede's national culture is still lacking.Design/methodology/approachDrawing on nine theories and models, this meta-analysis aims to summarize the findings reported in 109 s-commerce studies published between 2011 and 2021 and to examine the moderating role of national culture. The correlation coefficient (r) has been used as the main effect size for this study. Based on the random-effects method, the CMA V3 software has been employed to calculate the weighted mean effect sizes.FindingsThe meta-analysis results showed that all the 11 hypothesized direct relationships are positive and significant. The moderator results also revealed that five out of six cultural dimensions significantly moderate the examined associations.Originality/valueThis research serves to enrich the existing s-commerce literature by addressing contradictory and mixed results reported in the empirical studies. This study is one of the first of its kind to investigate the role of Hofstede's six cultural dimensions as moderators in the field of s-commerce using the meta-analytic techniques.
Cashew contract farming in Ghana: implications on farm performance and household welfare
Authors: Danso-Abbeam Gideon , Ogundeji Abiodun Akintunde , Fosu Samuel 
Published: August 2022

PurposeEfforts to reduce farmers' market risks and improve buyers' access to farm commodities have encouraged contract farming (CF) in Ghana's cashew sector in recent years. Consequently, the existence of CF shows that farmers who use it may be benefiting from it, as it is their economic responsibility to decide how to sell agricultural products. However, the magnitudes of these benefits or otherwise have been inadequately explored. This paper aims to empirically estimate the impact of CF on farm performance and welfare of smallholder cashew farmers.Design/methodology/approachThe study used probit-two-stage least square (probit-2sls) as a primary estimator to account for self-selection bias and endogeneity that could arise from both observed and unobserved heterogeneities among farming households to estimate the causal effects of CF on farm performance and household welfare.FindingsThe results indicated that participation in CF contribute significantly to the gains in farm performance (price margins, yields and net farm revenue) and welfare (consumption expenditure per capita), and that the non-participants of CF would have benefited substantially if they had participated. An analysis of the farm size disaggregated into small, medium and large with regards to the outcome variables produces mixed results.Research limitations/implicationsIt can be concluded that participating in CF enhances farm performance and household welfare.Originality/valueWhile many other studies do not account for changes in farm performance and welfare due to differences in farm size or other observed factors, this study fills a crucial void.
The mediating role of cooperative norms in the formation of buyer commitment in the buyer–seller relationship
Authors: Vieira Valter Afonso , Mayberry Robert , Boles James , Johnson-Busbin Julie , Pereira Rita Cassia 
Published: August 2022

Purpose
Drawing on Foa and Foa’s elaboration of social exchange theory, the authors propose that buyers reciprocate perceived commitment on the part of the salesperson and supplier with commitment on their own parts because of strengthening of the relationship’s tacit governance mechanism – cooperative norms.

Design/methodology/approach
This study uses data from 155 buyers doing business with a multinational supplier. The buyers were from firms generating less than $100,000 in billings. The salesforce of the supplier firm sponsoring the research is responsible for account management and communicating directly with buyers.

Findings
Buyers, who feel that their suppliers are providing a symbolic, long-term, particularistic benefit (commitment), respond with their own strengthened commitment to the relationship; this mutualism is explained entirely by the mediating effect of the relationship’s cooperative norms. Where buyers perceive generally favorable treatment (satisfaction), without these three qualities, their own reciprocal commitment increases directly and cooperative norms play no part. The results also demonstrate the transition of buyer perceptions of the salesperson as they develop into beliefs about the selling firm as a whole.

Practical implications
Drawing on the “reciprocation-in-kind” principle, supplier firms seeking long-term, open-ended commitment from their customers should cultivate it via similarly long-term and open-ended commitments of their own. Attention must be given to the unwritten, often unstated “rules of the road” for business relationships, as these rules represent the mechanism through which investments in long-term, profitable partnerships bear fruit.

Originality/value
The conceptual model draws on and empirically tests Foa and Foa’s framework within social exchange theory to predict what form of buyer reciprocation will result, based on the characteristics of perceived seller-provided benefits. This study illustrates that the tacit governance structure of a B2B relationship – its cooperative norms – plays a critical role in the strength of a buyer’s commitment to its supplier.
Role of customers’ multidimensional perceived equity in the mobile food delivery industry
Authors: Kwon Jookyung , Ahn Jiseon 
Published: August 2022

Purpose
Existing service research has revealed that customers’ perceived equity influences the sustainability of a business. Despite the importance of food service mobile applications during the COVID-19 pandemic, studies that have examined customers’ loyalty toward mobile applications remain limited. Thus, this study aims to examine the impact of mobile application-related attributes on customers’ behavior in the food delivery industry.

Design/methodology/approach
The authors collected data from 214 US customers to extend knowledge on perceived equity by examining the effect of multidimensional equity (i.e. value equity, brand equity and relationship equity) on loyalty in the mobile food service context.

Findings
Results of partial least square structural equation modeling suggest that three aspects of customers’ perceived equity are positively related to customers’ attitudinal loyalty, which is linked to behavioral loyalty. Moreover, the role of attitudinal loyalty and demographic characteristics (i.e. gender and age) is described.

Originality/value
This empirical research explores how food delivery brands can increase customers’ positive behavior by investigating the role of multidimensional equity. Service providers must understand certain aspects of customers’ perceived equity to increase food service brand sustainability.