bluuebunny/crossref_metadata_2025_split huggingface dataset:
Finite-temperature infinite matter with effective-field-theory-inspired energy-density functionals
Authors: Burrello Stefano , Grasso Marcella 
Published: February 2022

AbstractFinite-temperature infinite matter is analyzed with the recently introduced effective-field-theory(EFT)-inspired YGLO (Yang–Grasso–Lacroix–Orsay) and ELYO (extended Lee–Yang, Orsay) functionals, which are designed to describe very low-density regimes in symmetric (YGLO) and in pure neutron (YGLO and ELYO) matter. The article deals with neutron matter and aims to verify whether the use of these functionals allows us to correctly incorporate finite-temperature effects. We compare our results for some relevant thermodynamical quantities with the corresponding ones computed with a chosen reference ab-initio model, namely the many-body-perturbation-theory scheme. We validate the reliability of both EFT-inspired functionals at least at rather low densities and not too high temperatures and we discuss the effects related to the effective mass. We conclude that, at the present stage, the ELYO functional, having a higher neutron effective mass around saturation (closer to ab-initio values), allows us to describe finite-temperature properties more satisfactorily, in better agreement with ab-initio predictions up to higher densities and temperatures, compared to YGLO.
How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study
Authors: Widén Elisabeth , Junna Nella , Ruotsalainen Sanni , Surakka Ida , Mars Nina , Ripatti Pietari , Partanen Juulia J. , Aro Johanna , Mustonen Pekka , Tuomi Tiinamaija , Palotie Aarno , Salomaa Veikko , Kaprio Jaakko , Partanen Jukka , Hotakainen Kristina , Pöllänen Pasi , Ripatti Samuli 
Published: February 2022

Background:
Prediction tools that combine polygenic risk scores with clinical factors provide a new opportunity for improved prediction and prevention of atherosclerotic cardiovascular disease, but the clinical utility of polygenic risk score has remained unclear.

Methods:
We collected a prospective cohort of 7342 individuals (64% women, mean age 56 years) and estimated their 10-year risk for atherosclerotic cardiovascular disease both by a traditional risk score and a composite score combining the effect of a polygenic risk score and clinical risk factors. We then tested how returning the personal risk information with an interactive web-tool impacted on the participants’ health behavior.

Results:

When reassessed after 1.5 years by a clinical visit and questionnaires, 20.8% of individuals at high (>10%) 10-year atherosclerotic cardiovascular disease risk had seen a doctor, 12.4% reported weight loss, 14.2% of smokers had quit smoking, and 15.4% had signed up for health coaching online. Altogether, 42.6% of persons at high risk had made one or more health behavioral changes versus 33.5% of persons at low/average risk such that higher baseline risk predicted a favorable change (OR [CI], 1.53 [1.37–1.72] for persons at high risk versus the rest,
P
<0.001), with both high clinical (
P
<0.001) and genomic risk (OR [CI], 1.10 [1.03–1.17],
P
=0.003) contributing independently.

Conclusions:
Web-based communication of personal atherosclerotic cardiovascular disease risk-data including polygenic risk to middle-aged persons motivates positive changes in health behavior and the propensity to seek care. It supports integration of genomic information into clinical risk calculators as a feasible approach to enhance disease prevention.
Moving Towards Equity With Digital Health Innovations for Stroke Care
Authors: Verma Aradhana , Towfighi Amytis , Brown Arleen , Abhat Anshu , Casillas Alejandra 
Published: February 2022

Abstract:
Digital health has long been championed as a means to expanding access to health care. Now that the COVID-19 pandemic accelerated many health systems’ integration of digital tools for care, digital health may provide a path towards more accessible stroke prevention and treatment, particularly for historically disadvantaged patient populations. Stroke management is composed of multiple time points where digital health innovations have the potential to augment health access and treatment: from primary prevention, to the time-sensitive detection of ischemic stroke, administration of thrombolytic agents and consideration for endovascular interventions, to appropriate post-acute care, rehabilitation, and lifelong secondary stroke prevention—stroke care relies on a multidisciplinary and standardized approach. However, as we discuss pointedly in this Focused Update, underrepresented individuals face multilevel digital health disparities that potentially diminish the benefits of these digital advances. As such, these multilevel needs must be discussed and accounted for as health systems seek to integrate innovative and equitable digital health solutions towards stroke care.
Arctic Maritime Cyclone Distribution and Trends in the ERA5 Reanalysis
Authors: Chen Zihan , Lynch Amanda H. 
Published: February 2022

Abstract
We present a tracking algorithm for synoptic to meso-α-scale Arctic cyclones that differentiates between cold- and warm-core systems. The algorithm is applied to the ERA5 reanalysis north of 60°N from 1950 to 2019. In this dataset, over one-half of the cyclones that meet minimum intensity and duration thresholds can be classified as cold-core systems. Systems that undergo transition, typically from cold to warm core, make up 27.2% of cyclones and are longer lived. The relatively infrequent warm-core cyclones are more intense and are most common in winter. The Arctic-wide occurrence of maritime cyclones has increased from 1979 to 2019 when compared with the period from 1950 to 1978, but the trends have high interannual variability. This shift has ramifications for transportation, fisheries, and extractive industries, as well as impacts on communities across the Arctic.
Reconciling Conflicting Accounts of Local Radiative Feedbacks in Climate Models
Authors: Hedemann Christopher , Mauritsen Thorsten , Jungclaus Johann , Marotzke Jochem 
Published: February 2022

Abstract
The literature offers conflicting findings about which regions contribute most to increases in the global radiative feedback after a forcing increase. This paper explains the disagreement by discriminating between two common definitions of the local feedback, which use either local temperature or global temperature as their basis. Although the two definitions of feedback have been previously compared in aquaplanet models with slab oceans, here the definitions are compared for the first time in an atmosphere–ocean general circulation model (MPI-ESM1.2) integrated over four doublings of atmospheric CO2 concentrations. Large differences between the definitions can be seen in all feedbacks, but especially in the temperature and water vapor feedbacks. Differences of up to 10 W m−2 K−1 over the Southern Ocean can be explained by the pattern of surface warming, which weights the local feedbacks and reduces their contribution to the global mean. This finding is, however, dependent on the resolution of analysis, because the local-temperature definition is mathematically inconsistent across spatial scales. Furthermore, attempts to estimate the effect of “pattern weighting” by separating local feedbacks and warming patterns at the gridcell level fail, because the radiative change in key tropical regions is also determined by tropospheric stability via the global circulation. These findings indicate that studies of regional feedback change are more sensitive to methodological choices than previously thought, and that the tropics most likely dominate regional contributions to global radiative feedback change on decadal to centennial time scales.

Significance Statement
Radiative feedbacks are processes that either intensify or damp global surface warming. We compare two ways to define local radiative feedbacks in a climate model and find that the choice of definition drastically impacts the results. Differences in feedback between the definitions are up to 10 W m−2 K−1 over the Southern Ocean; by comparison, the estimate of the true global feedback is around −1 W m−2 K−1. Also, one of the definitions is mathematically inconsistent across different scales of spatial aggregation. Our findings matter because they help to reconcile disagreement in previous studies about which regions dominate global radiative feedback change in model simulations of global warming.
Modeling the Convective Boundary Layer in the Terra Incognita: Evaluation of Different Strategies with Real-Case Simulations
Authors: Giani Paolo , Genton Marc G. , Crippa Paola 
Published: February 2022

Abstract
Modeling atmospheric turbulence in the convective boundary layer is challenging at kilometer and subkilometer resolutions, as the horizontal grid spacing approaches the size of the most energetic turbulent eddies. In this range of resolutions, termed terra incognita or gray zone, partially resolved convective structures are grid dependent and neither traditional 1D mesoscale parameterizations nor 3D large-eddy simulations closures are theoretically appropriate. Leveraging on a new set of one-way nested, full-physics multiscale numerical experiments, we quantify the magnitude of the errors introduced at gray zone resolutions in a real-case application and we provide new perspectives on recently proposed modeling approaches. The new set of experiments is forced by real-time-varying boundary conditions, spans a wide range of scales, and includes traditional 1D schemes, 3D closures, scale-aware parameterizations, and strategies to suppress resolved convection at gray zone resolutions. The study area is Riyadh (Saudi Arabia), where deep CBLs develop owing to strong convective conditions. Detailed analyses of our experiments, including validation with radiosonde data, calculations of spectral features, and partitioning of turbulent fluxes between resolved and subgrid scales, show that (i) grid-dependent convective structures entail minor impacts on the first-order characteristics of the fully developed boundary layer due to some degree of implicit scale awareness of 1D parameterizations and (ii) 3D closures and scale-aware schemes outperform traditional 1D schemes especially in the surface layer, among other findings. The new suite of experiments provides a benchmark of real simulations that can be extended to assess how new turbulence closures perform at gray zone resolutions.

Significance Statement
As recent advances in high-performance computing are leading to a new era in numerical simulations, regional atmospheric models can now increase their resolution to the widely unexplored kilometer and subkilometer range. While increasing the resolution of atmospheric models is desirable to (i) have more realistic weather and air quality predictions and (ii) better represent boundary conditions for microscale models, kilometer and subkilometer grid spacings pose some theoretical challenges that need to be addressed by the atmospheric modeling community. In this work we run a set of numerical experiments for a real case study that aim to offer new perspectives on recently developed modeling strategies and identify the most promising directions that should be investigated by follow-up studies.
The Meteorology of the Tathra Bushfire
Authors: Wilke David J. , Kepert Jeffrey D. , Tory Kevin J. 
Published: February 2022

Abstract
The meteorological conditions over the South Coast of New South Wales, Australia, are investigated on 18 March 2018, the day of the Tathra bushfire. We present an analysis of the event based on high-resolution (100- and 400-m grid-length) simulations with the Bureau of Meteorology’s ACCESS numerical weather prediction system and available observations. Through this analysis we find several mesoscale features that likely contributed to the extreme fire event. Key among these was the development of horizontal convective rolls, which emanated from inland and aided the fire’s spread toward Tathra. The rolls interacted with the terrain to produce complex regions of strongly ascending and descending air, likely accelerating the lofting of firebrands and potentially contributing to the significant lee-slope fire behavior observed. Mountain waves, specifically trapped lee waves, occurred on the day and are hypothesized to have contributed to the strong winds around the time the fire began. These waves may also have influenced conditions during the period of peak fire activity when the fire spotted across the Bega River and impacted Tathra. Finally, the passage of the cold front through the fireground was complex, with frontal regression observed at a nearby station and likely also through Tathra. We postulate that interactions between the strong prefrontal flow and the initially weak change resulted in highly variable and dangerous fire weather across the fireground for a significant period after the change initially occurred.

Significance Statement
The town of Tathra on the South Coast of New South Wales, Australia, was devastated on 18 March 2018, when a wildfire ignited in nearby bushland and quickly intensified to impact the town. Using high-resolution numerical weather simulations, we investigate the conditions that led to the extreme fire behavior. The simulations show that the fire ignited and intensified under highly variable conditions driven by complex interactions between the flow over nearby mountains and the passage of a strong cold front. This case study highlights the value of such models in understanding high-impact weather for the purpose of hazard preparedness and emergency response. Additionally, it contributes to a growing number of case studies that indicate the future direction of high-impact forecast services.
Relationship Between Blood Lipid Levels and Mortality in Hospitalized COVID-19 Patients
Authors: Aydın Sidar Ş , Aksakal Emrah , Aydınyılmaz Faruk , Gülcü Oktay , Saraç İbrahim , Kalkan Kamuran , Aydemir Selim , Doğan Remziye , Aksu Uğur , Tanboğa İbrahim H 
Published: February 2022

People with comorbid conditions are at increased risk of developing severe/fatal coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between lipid levels and mortality in patients hospitalized for COVID-19 infection. In this retrospective study, we collected the details of 5274 COVID-19 patients who were diagnosed using the polymerase chain reaction and/or computed tomography and were hospitalized between March and November 2020. Patients (n = 4118) whose blood lipid levels were checked within the first 24 h after hospitalization were included in the study. Multivariable cox proportional hazards regression was used to assess the relationship between lipid variables such as low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) and death. There was a statistically significant association between LDL-C, HDL-C, and TG levels and the risk of death ( P =.002, <.001, and .035, respectively). Low and high LDL-C, low HDL-C, and high TG levels were negatively associated with COVID-19-related mortality. Blood lipid levels may be useful predictors of mortality in COVID-19 patients.
Recidivism of Low-Risk People That Receive Residential Community-Based Correctional Programs: The Role of Risk Contamination
Authors: Ostermann Michael 
Published: February 2022

Objectives Placing low-risk individuals into residential community-based correctional programs often results in minimal or iatrogenic impacts upon recidivism. Contamination through exposure to higher-risk program participants is a mechanism that has been used to explain these effects. This study empirically explores this phenomenon. Methods A series of survival models examine data from low-risk paroled people released from a state’s prisons from 2005 to 2011 (n = 3,862) to assess the impact of residential community-based program participation upon recidivism. The daily rate of exposure to higher-risk people while attending programs is modeled for a subset of program participants (n = 202) to assess impacts upon time to failure within 18-months of program completion. Results Program participation increased the hazards of failure by approximately 66% for low-risk paroled people. Exposure to higher-risk people did not have significant impacts upon recidivism. Conclusions The current study coincides with past work demonstrating that policy makers and practitioners should be mindful of the potential iatrogenic or minimal recidivism effects associated with treating low-risk people through residential community-based programs. The mechanisms by which these effects are produced are in need of further exploration. Particular attention should be paid to whether programs can disrupt pro-social aspects of low-risk peoples’ lives.
Vision Rehabilitation Therapists Teaching Technology: Association Between Their Age and the Frequency at Which Technology Job Tasks Are Performed
Authors: Connors Elyse M. , Pavone Rachel C. 
Published: February 2022

Introduction This study seeks to examine the association between the age of the Vision Rehabilitation Therapist (VRT) and the frequency at which they carry out technology job tasks. Methods A secondary data analysis was performed, using chi square to test for an association between the age of the VRT and the frequency at which they carry out 11 specific job tasks related to technology. Results Age of the VRT was shown to be negatively associated with the frequency at which 6 of the 11 technology job tasks are performed. Discussion Overall, younger VRTs are teaching access technology at higher frequencies than older VRTs. Newer specific technologies are being taught more often by younger VRTs, such as mobile technologies, voice-controlled devices, and social media. Older technologies such as keyboarding and OCR are being taught at similar frequencies regardless of age. Given the aging population of VRTs and the small number of university VRT programs, it may not be sustainable to rely on recent graduates or younger VRTs to fulfill access training needs for persons with visual impairment. With the availability, affordability, and quick emergence of new technologies, it is critical that all VRTs have access to continuing education to become comfortable and proficient in teaching newer technologies. Implication for Practitioners Technology training is critical for employment and independence for many persons with vision impairment. Continuing education for VRTs to be comfortable and competent in teaching emerging technologies may be important in ensuring that access technology training is available to all persons with visual impairment.
Care Pathways, Health Service Use Patterns and Opportunities for Justice Involvement Prevention Among Forensic Mental Health Clients
Authors: Leclair Marichelle C. , Charette Yanick , Caulet Malijaï , Crocker Anne G. 
Published: February 2022

Objectives The objective of the present study is to describe the patterns of health service use and of prescription claims in the year preceding an offense leading to a verdict of not criminally responsible on account of a mental disorder (NCRMD). Methods Provincial health administrative databases were used to identify medical services, hospitalizations, and ambulatory prescription claims among 1,014 individuals found NCRMD in Québec. Contacts in the year preceding the offense were analyzed using descriptive analyses and latent class analysis. Results Overall, 71.4% of subjects were in contact with services for mental health reasons within a year of their NCRMD offense. Among those that received services and not hospitalized for psychiatric reasons at the time of the offense, 20.7% committed the NCRMD offense within a week of the most recent mental health contact. Among those that had at least one prescription claim for an antipsychotic, 45.8% were not taking any antipsychotic at the time of the offense. Latent class analysis provided a multidimensional representation of mental health service use and showed that 58.4% of subjects had no or very rare contact with services. Conclusions Many forensic patients are likely to have experienced service disruption or discontinuity while in the community, for reasons that may relate to perceived need for care, to service organization, or to the acceptability, availability, and accessibility of services. Given the serious impact of the “forensic” label on the lives of service users, not to mention the increased pressure on resources, the considerable economic costs, and the impact on victims, there is reason to advocate for a greater involvement of mental and physical health service providers in early prevention of violence, which requires reorganizing resources to share the forensic knowledge upstream, before an offense is committed.
“Till Death Do Us Part”, Dying Matters, Beyond the Individual: Advance Care Planning Patterns Among Older Couples
Authors: Lee Hyo Jung , Kim Bon 
Published: February 2022

Objective We examined the formal and informal advance care planning (ACP) patterns of older couples and determined how these patterns are associated with individual and spousal characteristics. Methods Using data from the 2014 and 2016 Health and Retirement Study, we performed latent class analysis to identify ACP patterns and multinomial regression models to describe characteristics of older couples ( N = 2195 couples). Results We identified four ACP patterns: high engaging couple (47%); high engaging husband—low engaging wife (11%); high engaging wife—low engaging husband (11%); and low engaging couple (31%). High engaging couples were more likely to be older, educated, and financially better off, whereas high ACP engagement in discordant ACP patterns was associated with health and wives’ constraints. Discussion A couple-based approach was recommended to promote the merits of ACP where spouses were older, had limited resources, or where one or both partners were suffering from poor health.
The association between patient satisfaction with information and adherence to oral anticancer agents
Authors: Melis Eward J , Zwart-van Rijkom Jeannette EF , Egberts Toine CG , van den Bemt Bart JF , Witteveen Petronella O , Gardarsdottir Helga 
Published: February 2022

Introduction Adherence to anticancer agents is a critical factor in achieving adequate clinical response, and became a major challenge for patients and caregivers since the increased substitution of parenteral cytostatic by oral drugs. One of the factors that influences adherence is how well informed patients are about their therapy. This study assesses the association between patient satisfaction with information about oral anticancer agents and adherence. Materials and Methods This study was conducted among patients (≥18 years) who began oral anticancer therapy. Patients satisfaction with information and adherence were assessed using validated questionnaires. Adherence was also assessed using refill data. Logistic regression was applied to assess the association between overall patient satisfaction with information and both self-reported adherence and adherence based on an MPR value of above 80%. Results In total, 124 patients were included in the study. The median (IQR) satisfaction with information was 15.0(4) on a scale of 0–17. Eighty-two percent of participants reported adherence, while the refill data demonstrated that 64.5% of patients had an adherence rate of 80% or higher. Overall satisfaction with information was not significantly associated with self-reported adherence (OR adj 0.98 [95% CI 0.85–1.15]) or refill-based adherence (OR adj 1.11 [95% CI 0.99–1.24]). Conclusion The findings indicate no significant relationship between patient satisfaction with information and adherence. The population was highly satisfied with information about the oral anticancer agents, which indicates a high level of satisfaction with usual care. However, the refill data reveals that 35.5% of patients were not adherent.