bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fatal Venous Gas Embolism During Endoscopic Retrograde Cholangiopancreatography After Simultaneous Deployment of 2 Self-Expandable Metallic Stents
Authors: Chuang Justin , Kuang Rebecca , Ramadugu Ajit , Patel Dipen , Sharma Sachit , Shrestha Kishan , Burlen Jordan , Nawras Ali 
Published: October 2022

ABSTRACT
Gas embolisms are a rare complication of endoscopic retrograde cholangiopancreatography (ERCP). While there have been multiple reports of ERCP-associated air embolisms, only 2 case reports using oral cholangioscopy and CO2 insufflation have been reported in the literature. We present a unique case of a fatal CO2 venous air embolism during ERCP without using cholangioscopy and with no intentional CO2 insufflation of the biliary tree.
Open-Capsule Budesonide for the Treatment of Isolated Immune Checkpoint Inhibitor-Induced Enteritis
Authors: Hussain Nadeen , Robert Marie , Al-Bawardy Badr 
Published: October 2022

ABSTRACT
Immune checkpoint inhibitors (ICIs) have revolutionized the management of various advanced-stage malignancies. The utilization of ICIs can be limited by their immune-related adverse events such as diarrhea and enterocolitis. Isolated ICI-induced enteritis is an uncommon presentation compared with ICI-induced colitis/enterocolitis. ICI withdrawal and systemic corticosteroids can lead to resolution of enterocolitis in up to 70% of patients. We present a rare case of isolated ICI-induced enteritis refractory to high-dose systemic corticosteroids and responsive to a course of open-capsule budesonide only.
Techno-Economic Assessment of a 100 kWp Solar Rooftop PV System for Five Hospitals in Central Southern Thailand
Authors: Khamharnphol Rawit , Kamdar Ismail , Waewsak Jompob , Chiwamongkhonkarn Somphol , Khunpetcha Sakrapee , Kongruang Chuleerat , Gagnon Yves 
Published: October 2022

This paper presents a techno-economic assessment of a 100 kWp solar rooftop photovoltaic (PV) system at five hospitals in central southern Thailand. The system encompasses 100 kWp PV panels, 100 kW grid-tied inverters and balance of system (BOS) under the grid code of the Provincial Electricity Authority (PEA). The latest PV technology of bifacial mono-crystalline solar panels, inverters and BOS were simulated along with the Meteonorm 7.3 database using the PVsyst simulation toolkit with different tilt angles, orientations, solar radiations and ambient temperature. The technical aspects of solar rooftop PV power generation systems include the annual energy output and the performance ratio (PR) under IEC standard. Further, an economic analysis of the model was examined using a cost benefit analysis (CBA) and various assumptions. Four main financial criteria, i.e., benefit cost ratio (BCR), net present value (NPV), internal rate of return (IRR), and payback period (PBP) were evaluated under three different scenarios: (1) self-consumption scheme, (2) feed-in tariff (FiT) scheme, and (3) private power purchase agreement (PPA) scheme. Finally, the levelized cost of energy (LCOE) was also calculated. The results reveal that the Takua Thung hospital is characterized by the maximum average global horizontal irradiation (GHI) and the maximum annual produced energy of 199 kWh/m2 and 164.8 MWh/year, respectively. The PR calculated for all hospital sites is above 85%. The outcomes of the financial analysis show that the optimum scenarios are PPA and FiT schemes. The LCOE analysed in this study indicates that the Takua Thung hospital site has the lowest LCOE at 2.47 THB/kWh (0.07 USD/kWh). This research confirms the potential for hospitals and stakeholders in central southern Thailand for investments in solar rooftop PV systems
Consistent Regime-Switching Lasso Model of the Biomass Proximate Analysis Higher Heating Value
Authors: Kijkarncharoensin Akara , Innet Supachate 
Published: October 2022

Prediction accuracy is crucial for higher heating value (HHV) models to promote renewable biomass energy, especially its consistency is crucial when retraining data and knowledge of the range are unavailable. Current HHV models lack consistency in accuracy and interpretability due to various reasons. Thus, this study aimed to construct an interpretable and consistent proximate-based biomass HHV model on a wide-range dataset. The model, regime-lasso, integrated the concepts of regime-switching, lasso regression, and federated averaging to construct a consistent HHV model. The regime-switching partitioned the dataset into optimal regimes, and the lasso trained the regime models. The regime-lasso model is a collection of these models. It provided root mean square error of 0.4430– 0.9050, mean absolute error of 0.2743–0.6867, and average absolute error of 1.512–4.5894% in the literature’s wide-range datasets. The Kruskal–Wallis test confirmed the in-sample performance consistency at α=0.05, regardless of the training sets. In the out-of-sample situations without retraining, the model preserved its accuracy in six out of 11 datasets at α = 0.01. The interpretability of regime-lasso indicated the regime characteristic to be a factor of inconsistent prediction. The increase in FC had the maximum positive impact on HHV in the 2nd and 3rd regimes, while the increase in ASH negatively impacted the 1st and 2nd regimes. VM variation had neutral effects in all regimes. The regime-lasso solves the issues of accuracy declination and addresses the challenges in sensitivity analysis of the HHV model. The prediction accuracy issues of the model’s direct implementation were fixed.
Expansão Urbana da zona sul de Ilhéus-BA: os condomínios fechados horizontais e a segregação
Authors: Lanza Fabiana Portilho de Resende , Batata Adriane Gomes Rodrigues 
Published: October 2022

Os processos de expansão urbana tanto nas cidades de médio porte, como nas de grande, têm sido influenciados por uma nova forma de produção do espaço urbano, os condomínios fechados. Cada vez mais presentes na paisagem das cidades, essa tipologia reflete o desejo de grupos sociais específicos que, estimulados pelo mercado imobiliário, impactam o tecido urbano e social estabelecendo diferentes formas de segregação. O trabalho busca contribuir para a discussão a respeito do impacto da proliferação e consolidação de condomínios fechados horizontais em cidades de médio porte, como o município de Ilhéus, BA. Os principais resultados encontrados sugerem certa ineficiência da administração pública municipal em fazer cumprir a legislação urbana, associada a uma forte pressão do mercado imobiliário em negociar a paisagem. Tal contexto resulta em diferentes processos de segregação, como o associado à mobilidade urbana.

PALAVRAS-CHAVE: Cidades médias. Produção do espaço. Segregação. Agentes sociais. Paisagem.
Cidade e Natureza: conflitos e alternativas para melhoria de problemas ambientais na cidade de Fernandópolis-SP
Authors: Macedo Larissa Martioli , Santos Thaís Vicente 
Published: October 2022

O espaço urbano e áreas verdes devem buscar uma integração harmônica para a construção de cidades ambientalmente saudáveis. Entretanto, possíveis desenhos benéficos entre área urbanizada e mais naturalizadas não têm sido adotados pelas cidades que suprem as áreas verdes e canalizam suas águas. Este é o caso de Fernandópolis, cidade do interior do estado de São Paulo, que invisibilizou seus córregos, têm uma ausência de áreas de preservação permanente e demais áreas verdejadas e sofre com problemas de drenagem urbana em diversos pontos de seu território. No entanto, existem possibilidades de redesenho de áreas já consolidadas, adotando medidas de infraestrutura verde, necessárias para evitar desastres ambientais e reintroduzir a vegetação em meio a infraestrutura cinza (concreto). Propôs-se assim, a análise de áreas críticas do município de Fernandópolis e adoção de tipologias verde como resolução dos problemas de enchentes.

PALAVRAS-CHAVE: natureza, cidade, infraestrutura verde.
Urbanização e Gestão do Território: A Barrinha Nos Séculos XX e XXI
Authors: Costa Maria de Lourdes Pinto Machado , Casut Pâmela Lack 
Published: October 2022

Este artigo contempla o entendimento do papel desempenhado pelo tradicional setor urbano do Rio de Janeiro - Barrinha, Largo da Barra ou Barra Antiga, situado na Barra da Tijuca, Zona Oeste da cidade. O objetivo principal da pesquisa cumpriu-se ao avaliar a formação histórica e diferenciação da Barrinha, de suas particularidades e identidade, que a faz exemplar na preservação de seus ambientes natural e construído, nessa microescala urbana, assim como a afirmação da aproximação de seus moradores mais antigos entorno de atuantes associações locais. A metodologia se pautou pelo tratamento qualitativo e quantitativo de dados e informações, na aproximação com a realidade representada e transparecida. As conclusões responderam ao escopo da investigação desenvolvida sobre o percurso trilhado de uso e ocupação de seus espaços, a formação de sua morfologia, as caraterísticas que marcaram o percurso de sua urbanização, paralelamente ao constatado por seu crescimento, no contexto do bairro em que se inscreve. Mapas e fotos subsidiam análises e resultados.

PALAVRAS-CHAVE: Urbanização, identidade, preservação, Barrinha, Barra da Tijuca, Rio de Janeiro.
Ações Sociais em um Parque Urbano da Zona Leste da Cidade De São Paulo Durante A Pandemia De Covid-19
Authors: França José Ulisses Bezerra de , Nascimento Ana Paula Branco do , Marinho Francisca Jane Furtado , Régis Milena de Moura , Simões André Felipe 
Published: October 2022

O momento pandêmico proporcionou o fortalecimento de ações sociais voltadas à população de comunidades com alto índice de vulnerabilidade social. Dentre os princípios da sustentabilidade urbana, está a mitigação das disparidades sociais, assunto relevante no planejamento urbano sustentável. A presente pesquisa, neste contexto, tem como objetivo relatar os serviços socioambientais oferecidos por um parque urbano durante a ainda vigente Pandemia de COVID-19; o recorte espacial escolhido, em vista da considerável disponibilidade de dados primários, foi o Parque Municipal Jardim da Conquista (PMJC), localizado na Zona Leste da cidade de São Paulo não. Trata-se de uma pesquisa descritiva e exploratória que observou, registrou, analisou e correlacionou eventos e fatos, além de usar procedimentos técnicos documentais para descrever de forma qualitativa as ações sociais realizadas no e pelo parque. O isolamento social, consequência da pandemia em curso, implicou, via de regra, no fechamento de parques urbanos, mesmo assim, o PMJC não interrompeu a prestação de serviços socioambientais aos cidadãos e passou a protagonizar, além desses serviços, determinadas ações sociais que beneficiaram cerca de seis mil famílias residentes em favelas na Zona Leste da cidade e na Região Metropolitana de São Paulo (RMSP). Fato este que apontou para a possibilidade de os parques públicos urbanos também serem espaços de promoção de ações socioambientais as quais mitiguem externalidades negativas associáveis à vulnerabilidade social de moradores dessas regiões. As parcerias com a Central Única das Favelas (CUFA), com Organizações Não Governamentais (ONGs) locais e com lideranças regionais, que atuaram enquanto colaboradores para a efetivação das ações, tornaram o supracitado parque urbano o pioneiro na condição de entreposto para o recebimento e distribuição de doações (por exemplo de gêneros alimentícios, cobertores e botijões de gás) a esta população tipicamente vulnerável.

Palavras-chave: Espaços Verdes. Parques Urbanos. Cidade de São Paulo. Pandemia de COVID-19. Vulnerabilidade. Sustentabilidade Urbana. Mitigação de Desigualdades Sociais.
Inhibitory activity of aqueous extracts of tea compositions, individual ingredients for their preparation and some plants against replication of Herpes simplex virus type 2 <i>in vitro</i>
Authors: Каzachinskaia E. I. , Chepurnov A. A. , Shelemba A. A. , Guseinova S. A. , Magomedov M. G. , Коnonova Yu. V. , Romanyuk V. V. , Shestopalov A. M. 
Published: October 2022

Aim. In vitro analysis of the inhibitory activity of aqueous extracts of tea compositions, plant raw materials and as well as plants from different families against replication of Herpes simplex virus type 2.Material and Methods. The viral strain MS of HSV‐2 was passivated on Vero cell culture. Antiviral (inhibitory) activity of aqueous extracts was studied in vitro according to the classical scheme of neutralization (inactivation) of the virus.Results. For comparison we used control samples of aqueous extracts of Chaga mushroom (Inonotus obliquus) and grass of Alchemilla vulgaris L. with EC50 equal to 21.36±3.92 and 39.67±8.75 µg/ml (for dry raw materials) versus 103 PFU/ml HSV‐2. As a result the prevailing activity (from 15.25±3.92 to 1.71±0.54 µg/ml) was identified for extracts of tea compositions based on black and green tea, as well as individual ingredients for their composition – black tea, leaves of Mentha piperita L., flowers of Lavandula angustifolia Mill. and clove spices (Syzygium aromaticum L.). Extracts obtained from plants that are not part of tea compositions of interest are fermented leaves of Epilobium angustifolium L. (Onagraceae) and grass of two species Euphorbia (E. pilosa L. and E. esula L., Euphorbiaceae) with inhibitory activity at concentrations of 10.675±1.96; 2.29±0.57 and 1.71±0.54 µg/ml, respectively.Conclusion. The results presented can become the basis for the search for individual biologically active substances of plant origin that inhibit HSV‐2 replication as well as for the development of effective medicines in the form of tea beverages and/or formulations for topical use to reduce relapses of chronic herpes.
Biological agents and their metabolites to control <i>Meloidogyne</i> spp. when growing vegetables (review)
Authors: Churikova A. K. , Nekoval S. N. 
Published: October 2022

Aim. Analysis of modern studies on the effectiveness of fungi and antagonist bacteria against Meloidogyne root‐knot nematodes on vegetable crops.Materials and Methods. Studies of Russian and foreign scientists on the use of biological agents and their metabolites to control Meloidogyne spp. when growing vegetables have been carefully analysed.Results. The harmfulness of gall nematodes on vegetable crops is described. Studies on the most pathogenic species of Meloidogyne, including those common in Russia, are summarised. Information is given regarding features of the relationship between the host plant and phytoparasites are highlighted. An analysis of the range of chemical and biological nematicides is presented. The problem of the lack of effective environmentally friendly products able to control root‐knot nematodes on vegetables, including the prospect of using biological agents, has been identified. The features of ongoing research on the study of the nematicidal activity of biological agents and their metabolites to control various stages of development of Meloidogyne species have been collected, analysed, systematised and described. The prospect of studying the mechanisms of action of microorganisms against root‐knot nematodes is substantiated in order to create new effective biological nematicides that allow the growth of high‐quality and healthy vegetable products.Conclusion. Gall nematodes (Meloidogyne spp.) remain a current pest of soil‐grown vegetables. Scientists are actively working on the study of nematophagous fungi and antagonist bacteria to create environmentally friendly biological nematicides. With proper use, biological agents and their metabolites can help protect plants from phytoparasites at the level of chemical nematicides and have an additional beneficial effect on the growth and development of vegetable crops.
The modern green course of Russia: problems and prospects of implementation
Authors: Gadzhiev N. G. , Konovalenko S. A. , Trofimov M. N. , Rozhkova N. V. , Saipullaev A. M. 
Published: October 2022

Aim. To study the impact of the Green Deal of Russia program on the development of the country's economy, to analyze the main problems and prospects for its implementation in the medium and long term.Methods. The study was conducted using theoretical system analysis, induction, deduction, comparative‐descriptive analysis, general scientific method of accounting.Results. Currently, the most dynamically developing countries of the world are looking for ways to ensure the establishment and development of a green economy and the conservation of existing biodiversity in ecosystems. The Russian Green Deal project is a large‐scale concept for the development of the country until 2050 with an emphasis on decarbonizing the economy and restoring the environment. The authors made an attempt to answer the question, what are the prospects for the implementation of the "Green Course of Russia" program in the country. The implementation of the strategic initiatives of the "Green Deal of Russia", according to the study, will require significant both current and investment costs. The authors concluded that it is necessary to carry out a set of organizational, rule‐making, administrative and managerial measures on the part of the state and society aimed at structural modernization of the entire socio‐economic system of the country.Conclusion. The need to implement the main provisions of the "Green Deal for Russia" program is beyond doubt, as the whole world is facing serious global environmental challenges that can destroy humanity itself. At the same time, the issue of readiness for the structural modernization of the Russian economy through the transition to the development of clean energy, energy efficiency, and the development of a cyclical economy remains open and uncertain.
Cryptolemus in the integrated fight against the Australian Grooved Worm (<i>Icerya purchasi</i> Mackall)
Authors: Bugaeva L. N. , Kashutina E. V. , Ignateva T. N. 
Published: October 2022

Aim. To study the possibility of using cryptolemus in an integrated system for combating the Australian grooved worm in the conditions of the southern coast of Crimea.Material and Methods. The population of Icerya purchasi Mackall on plants was determined during regular surveys of agrobiocenoses by counting the number of pest individuals per unit area. The biological effectiveness of cryptolemus from the unique scientific installation «State collection of living entomoacariphages and entomopathogens» in relation to the Australian grooved worm on pittosporum in the conditions of the Southern Coast of Crimea was studied in the following variants: beetle release, larval release and joint release of imago and predator larvae. The possibility of joint use of bioagent and pesticides was studied in the laboratory according to generally accepted methods.Results. It was established that the biological efficacy of Cryptolaemus montrouzieri Muls. in relation to Icerya purchasi Mackall in the conditions of the Southern Coast of Crimea amounted to 50–75% and the possibility of joint use of an entomophage with a number of pesticides is also shown.Conclusion. The potential possibility of controlling the pest population with a bioagent, without the use of chemical means of protection, which is especially important in the conditions of a resort area, has been experimentally proven.
Epi-Clock: A sensitive platform to help understand pathogenic disease outbreaks and facilitate the response to future outbreaks of concern.
Authors: Ji Cong , Shao Junbin (Jack) 
Published: October 2022

Abstract
Determining how viruses originated and diverged and how infectious diseases are transmitted are serious challenges. Surprisingly, some inter-species genetic distances among Coronaviridae were shorter than intra-species distances, possibly representing the intermediate states of different species or subspecies in the evolutionary history of Coronaviridae. The indels of whole genome sequences between different hosts were separately associated with new functions or turning points, clearly indicating their important roles in the host transmission and shifts of Coronaviridae. Furthermore, we believe that non-nucleosomal DNA may play dominant roles in the divergence of different lineages of SARS-CoV-2 in different regions of the world because of the lack of nucleosome protection. We suggest that strong selective variation among different lineages of SARS-CoV-2 is required to produce strong codon usage bias. Interestingly, we found that an increasing number ofother types of substitutions, such as those resulting from the hitchhiking effect, have accumulated, especially in the pre-breakout phase. Topredict potential epidemic outbreaks, we tested our strategy, Epi-Clock, which applies the ZHU algorithm on different SARS-CoV-2 datasets to search for real significant mutational accumulation patterns correlated with the outbreak events. We could accurately predict the potential pre-phase of outbreaks with a median interval of 5 days before the outbreaks. Using our pipeline, users may review updated information on the website https://bioinfo.liferiver.com.cnwith easy registration. Therefore,we propose Epi-Clock, a sensitive platform similar toa clock that can signal the need to assist individuals at focal locations by using diagnostics, isolation control, vaccines or therapy at any time.
The Solar Asymmetric Activity – Does The Sun Have a Face?
Authors: Mizrahi Ezra , Hazan Suzan 
Published: October 2022

Abstract
The east-west asymmetrical, longitudinal distribution of solar activity has a long history, and has been recorded for prolonged periods.
In order to explore these observations further this paper focuses on the space and time, of magnetic fluxes in the photosphere that were harvested from images and data from the SOHO/MIDI magnetogram during 2006. Our research documented the distribution of the time and the location of the birth of sunspots, while taking into consideration evidence from other tracers, and comparing them to other solar activity observations.
The fluxes’ longitudinal distribution indicates east-west asymmetry and shows remarkably similar behavior to other observational results that have been observed over prolonged periods. Distinguishing between initial and advanced stages demonstrates how most fluxes near the east limb are brought into view in their formation stage .
The preponderance of “new” fluxes on the Eastern limb indicates an active longitude belt on the Eastern side thereby causing E-W asymmetry.
When observed from an Earth-located perspective, the evidence of east-west asymmetry leads us to conclude that the active longitudinal belt can only exist on one side of the hemisphere and, in fact, can be observed only from an Earth-located perspective.
In order to further explore these observations, our research draws on the 2006 results to calculate how the same photospheric activity pattern would be viewed from the perspective of the planets Mars and Venus; as if using virtual observers. In contrast to the Earth-located observer, our calculations indicate an apparent random spread of sunspot longitudinal distribution, with no clear evidence of an active longitudinal belt, and no evidence of an east-west asymmetry as observed from Earth. This empirical evidence leads us to suggest that the sun has a face.