bluuebunny/crossref_metadata_2025_split huggingface dataset:
The “Mellanby effect” in alcoholised e-scooter drivers
Authors: Zube Katharina , Lau Michael , Daldrup Thomas , Bruch Gina Maria , Tank Anne , Hartung Benno 
Published: November 2022

Abstract

Purpose
Several studies tried to discuss and clarify the so-called Mellanby effect: Similar blood alcohol concentrations (BACs) supposedly lead to more signs of impairment in the phase of alcohol resorption than elimination. To assess this effect for alcoholised e-scooter driving, results of a real-driving fitness study were subanalysed.

Methods
Sixteen subjects (9 females; 7 males) who completed runs at comparable BACs in the phases of alcohol resorption and elimination were chosen to assess a possible “Mellanby effect”. The data of the subjects was taken from a prior e-scooter study by Zube et al., which included 63 subjects in total.

Results
In the phase of alcohol resorption, the relative driving performance was approx. 92% of the phase of elimination (p value 0.21).
Statistically significant more demerits were allocated to the obstacle “narrowing track” in the phase of resorption than elimination.
Subjects also needed significantly more time to pass the obstacles “narrowing track”, “driving in circles counterclockwise” and “thresholds” in the phase of resorption than elimination.

Discussion
The most relevant obstacle to discriminate between the two different states of alcoholisation was the narrowing track. Insofar, measurements of the standard deviation of the lateral position (SDLP) might also be a sensitive component for the detection of central nervous driving impairment during shorter trips with an e-scooter.
Additionally, driving slower during the phase of alcohol resorption seems to be the attempt to compensate alcohol-related deficits.

Conclusion
The results of the study suggest a slight Mellanby effect in e-scooter drivers.
The multisensory nature of human action imagery
Authors: Krüger Britta , Hegele Mathias , Rieger Martina 
Published: November 2022

AbstractImagination can appeal to all our senses and may, therefore, manifest in very different qualities (e.g., visual, tactile, proprioceptive, or kinesthetic). One line of research addresses action imagery that refers to a process by which people imagine the execution of an action without actual body movements. In action imagery, visual and kinesthetic aspects of the imagined action are particularly important. However, other sensory modalities may also play a role. The purpose of the paper will be to address issues that include: (i) the creation of an action image, (ii) how the brain generates images of movements and actions, (iii) the richness and vividness of action images. We will further address possible causes that determine the sensory impression of an action image, like task specificity, instruction and experience. In the end, we will outline open questions and future directions.
Movement disorders in hereditary spastic paraplegia (HSP): a systematic review and individual participant data meta-analysis
Authors: Fereshtehnejad Seyed-Mohammad , Saleh Philip A. , Oliveira Lais M. , Patel Neha , Bhowmick Suvorit , Saranza Gerard , Kalia Lorraine V. 
Published: November 2022

Abstract
Background

Hereditary spastic paraplegia (HSP) is a rare genetic disorder associated with mutations in > 80 loci designated SPG (SPastic parapleGia). The phenotypic spectrum of HSP can extend to include other neurologic features, including movement disorders. Our aim was to investigate genotype–phenotype associations in HSP with a focus on movement disorders.

Methods
We performed a systematic review and individual participant data (IPD)-level meta-analysis by retrieving publications from Medline/EMBASE/Web of Science on HSP with a SPG genotype. Studies were included only if individual-level information was accessible and at least one patient with a movement disorder was reported for that genotype. Out of 21,957 hits, 192 manuscripts with a total of 1413 HSP cases were eligible. Data were compared between two HSP groups: manifested with (HSP-MD, n = 767) or without (HSP-nMD, n = 646) a movement disorder.

Results
The HSP-MD group had an older age of onset (20.5 ± 16.0 vs. 17.1 ± 14.2 yr, p < 0.001) and less frequent autosomal dominant inheritance (7.6% vs. 30.1%, p < 0.001) compared to HSP-nMD. SPG7 (31.2%) and SPG11 (23.8%) were the most frequent genotypes in the HSP-MD group. HSP-MD with SPG7 had higher frequency of later onset during adulthood (82.9% vs. 8.5%), ataxia (OR = 12.6), extraocular movement disturbances (OR = 3.4) and seizure (OR = 3.7) compared to HSP-MD with SPG11. Conversely, SPG11 mutations were more frequently associated with consanguinity (OR = 4.1), parkinsonism (OR = 7.8), dystonia (OR = 5.4), peripheral neuropathy (OR = 26.9), and cognitive dysfunction (OR = 34.5).

Conclusion
This systematic IPD-level meta-analysis provides the largest data on genotype–phenotype associations in HSP-MD. Several clinically relevant phenotypic differences were found between various genotypes, which can possibly facilitate diagnosis in resource-limited settings.
Gender Differences in HIV, HCV risk and Prevention Needs Among People who Inject drug in Vietnam
Authors: Giang Hoang Thi , Duc Nguyen Quang , Khue Pham Minh , Quillet Catherine , Oanh Khuat Thi Hai , Thanh Nham Thi Tuyet , Vallo Roselyne , Feelemyer Jonathan , Vinh Vu Hai , Rapoud Delphine , Michel Laurent , Laureillard Didier , Moles Jean Pierre , Jarlais Don Des , Nagot Nicolas , Huong Duong Thi 
Published: November 2022

AbstractWe examined gender differences among people who inject drug (PWID) in Hai Phong, Vietnam in term of blood-borne infections, risk behaviors, and access to care. Using respondent-driven-sampling surveys, we recruited 3146 PWID from 2016 to 2018. Inclusion criteria included a positive urine test for heroin and recent injection marks. There were 155 female PWID (4,9%), including 82 at RDS-2016, 32 at RDS-2017 and 38 at RDS-2018. The age mean was 36.3 ± 7.2 years. The majority of female PWID had less than high school education (90.9%) and were unemployed (51.3%). There was no difference in the proportion of HIV and HCV positive by gender. However, women had several significant differences in risk behaviors than men in multivariable logistic regression. Being a woman was independently associated with being unemployed, being a sex worker, having unstable housing, having uses drugs for less than 5 years, more use of methamphetamine, having a partner who ever injected drugs, and less access to methadone treatment. Interventions targeting female PWID are needed, possibly through community organizations and peer educators.
Virtual field trips in hydrological field laboratories: The potential of virtual reality for conveying hydrological engineering content
Authors: Grosser Paula Farina , Xia Zhongxin , Alt Jannik , Rüppel Uwe , Schmalz Britta 
Published: November 2022

AbstractWith the start of the COVID-19 pandemic and the resulting contact restrictions, conducting field trips to hydrological research basins became close to impossible. Hydrological field knowledge is an essential part of hydrological education and research. In order to impart this knowledge to students of hydrological engineering subjects in times or situations where on-site exploration is not possible, the VR4Hydro tool was developed. VR4Hydro is a virtual reality platform built from 360° panoramas that allows users to interactively explore the Gersprenz River basin in Germany. The following study seeks to investigate the applicability of performing virtual field trips in the context of hydrological education by evaluating user experience. Sixteen students of the subject engineering hydrology were asked to document their experiences with VR4Hydro using a qualitative approach by answering a series of multiple-choice questions as well as long-answer text questions. The analysis and discussion of the results showed that virtual excursions generally met with great interest among users. The majority rated the virtual tour as a valuable addition to traditional teaching methods. All students found the tool particularly appealing in cases where external circumstances did not allow for a real excursion. The findings of this study show that the application of virtual field trips (VFT) in hydrological engineering can be a valuable supplement to real field trips to improve the interest and learning outcome of students.
Do mothers get lost at the postdoc stage? Event history analysis of psychologists at German universities (1980–2019)
Authors: Habicht Isabel M. 
Published: November 2022

Abstract Women in academia are typically outnumbered by men, a phenomenon metaphorically known as “the leaky pipeline.” This study contributes by showing a motherhood penalty in the career pipeline at the postdoctoral stage in Germany—that is, during habilitation. Based on CV information and an email survey, the paper examines which factors are associated with being awarded a habilitation and whether these factors differ between women and men as well as mothers and fathers. Using Cox regressions of retrospective career trajectories of almost all psychologists at German universities in 2019 (2527 scientists with 37,423 publications), the study shows that SSCI/SCIE articles and having a PhD from abroad increase the habilitation risk more strongly for women and mothers than for men and fathers. Net of career factors observed by CVs, however, mothers have a 42% significantly lower habilitation risk.
Vulnerability Factors of Intimate Partner Violence Among Victims of Partner Only and Generally Violent Perpetrators
Authors: Edhammer Helene , Petersson Joakim , Strand Susanne J.M. 
Published: November 2022

Abstract
Purpose
The aim of this study was to examine how victims of intimate partner violence (IPV) differ in terms of vulnerability factors and risk of being re-victimized, by comparing victims of the two most consistently identified IPV male perpetrator subtypes: the Partner Only (PO) violent and the Generally Violent (GV).

Methods
The current study analyzed IPV reported to the Swedish police and consisted of a sample of 1479 cases of male-to-female perpetrated IPV. The material mainly consisted of IPV risk assessments conducted by the police.

Results
The results showed that vulnerability factors were significantly more common among victims of GV perpetrators, including inconsistent attitudes or behaviors, extreme fear of the perpetrator, inadequate support or resources, an unsafe living situation, and health problems. Moreover, victims of GV perpetrators were generally assessed by the police with a significantly higher risk of being re-victimized by IPV. Finally, in relation to the victim vulnerability factors most strongly associated with an elevated assessed risk for IPV re-victimization, the presence of extreme fear of the perpetrator and having an unsafe living situation were significantly related to such outcomes for both groups of victims.

Conclusion
In sum, the results of this study contribute to the scant body of knowledge on IPV victim subtypes and their vulnerability profiles. In addition to facilitating the risk assessment of repeated IPV, such knowledge could also indicate what type of support different victim subtypes require in order to prevent IPV.
6D object position estimation from 2D images: a literature review
Authors: Marullo Giorgia , Tanzi Leonardo , Piazzolla Pietro , Vezzetti Enrico 
Published: November 2022

AbstractThe 6D pose estimation of an object from an image is a central problem in many domains of Computer Vision (CV) and researchers have struggled with this issue for several years. Traditional pose estimation methods (1) leveraged on geometrical approaches, exploiting manually annotated local features, or (2) relied on 2D object representations from different points of view and their comparisons with the original image. The two methods mentioned above are also known as Feature-based and Template-based, respectively. With the diffusion of Deep Learning (DL), new Learning-based strategies have been introduced to achieve the 6D pose estimation, improving traditional methods by involving Convolutional Neural Networks (CNN). This review analyzed techniques belonging to different research fields and classified them into three main categories: Template-based methods, Feature-based methods, and Learning-Based methods. In recent years, the research mainly focused on Learning-based methods, which allow the training of a neural network tailored for a specific task. For this reason, most of the analyzed methods belong to this category, and they have been in turn classified into three sub-categories: Bounding box prediction and Perspective-n-Point (PnP) algorithm-based methods, Classification-based methods, and Regression-based methods. This review aims to provide a general overview of the latest 6D pose recovery methods to underline the pros and cons and highlight the best-performing techniques for each group. The main goal is to supply the readers with helpful guidelines for the implementation of performing applications even under challenging circumstances such as auto-occlusions, symmetries, occlusions between multiple objects, and bad lighting conditions.
An efficient compression technique for Foetal phonocardiogram signals in remote healthcare monitoring systems
Authors: Fathi Islam S. , Ahmed Mohamed Ali , Makhlouf M. A. 
Published: November 2022

AbstractRemote Healthcare Monitoring Systems (RHMs) that employ fetal phonocardiography (fPCG) signals are highly efficient technologies for monitoring continuous and long-term fetal heart rate. Wearable devices used in RHMs still face a challenge that decreases their efficacy in terms of energy consumption because these devices have limited storage and are powered by batteries. This paper proposes an effective fPCG compression algorithm to reduce RHM energy consumption. In the proposed algorithm, the Discrete Orthogonal Charlier Moment (DOCMs) is used to extract features of the signal. The householder orthonormalization method (HOM) is used with the Charlier Moment to overcome the propagation of numerical errors that occur when computing high-order Charlier polynomials. The proposed algorithm’s performance is evaluated in terms of CR, PRD, SNR, PSNR, and QS and provides the average values 18.33, 0.21, 48.85, 68.86, and 90.88, respectively. The results of the comparison demonstrate the proposed compression algorithm’s superiority over other algorithms. It also tested in terms of compression speed and computational efficiency. The results indicate that the proposed algorithm has a high Compression speed (218.672 bps) and high computational efficiency (21.33). Additionally, the results reveal that the proposed algorithm decreases the energy consumption of a wearable device due to the transmission time decreasing for data by 3.68 s.
Kommunal verankerte Versorgungsstrukturen zur Förderung der Ernährungsgesundheit in den ersten 1000 Tagen – eine Analyse des aktuellen Status quo
Authors: Schrameyer Lena , Wittler Linda , Schmidt Lisa , Wessely Stefanie , Flothkoetter Maria , Eiser Stefanie , Reiss Katharina , Paul Mechthild , Ferrari Nina , Joisten Christine 
Published: November 2022

Zusammenfassung
Ziel
Die Ernährung in den ersten 1000 Tagen stellt einen relevanten Einflussfaktor für eine gesunde (Gewichts)entwicklung von Kindern dar. Verhältnispräventive, kommunalbasierte Ansätze scheinen am Erfolg versprechendsten in der Bekämpfung von (kindlichem) Übergewicht bzw. nicht übertragbaren Erkrankungen zu sein. Ziel dieser Arbeit war es, Strategien zum Gelingen der Ernährungsgesundheit in den ersten 1000 Tagen herauszuarbeiten.

Methodik
Auf Basis einer internetbasierten Recherche möglicher kommunalbasierter Praxisprojekte wurden standardisierte, leitfadengestützte Interviews mit Expertinnen und Experten aus Wissenschaft und Praxis durchgeführt. Der Fokus lag auf der allgemeinen Einschätzung der Versorgungslage bzw. einem möglichen Handlungs- und Versorgungsbedarf sowie konkreten Handlungsempfehlungen unter besonderer Berücksichtigung von Schwangeren bzw. jungen Familien in belasteten Lebenslagen. 14 von 40 im Schneeballverfahren ausgewählten Personen nahmen teil.

Ergebnisse
Alle Teilnehmenden schätzen die aktuelle primärpräventive Versorgung als nicht ausreichend ein. Als kritisch wurden von ihnen v. a. die fehlenden strukturellen und politischen Rahmenbedingen, insbesondere die häufig bestehenden zeitlich begrenzten Programme, gesehen. Dadurch seien Maßnahmen zur Förderung der Ernährungsgesundheit oder vergleichbare Interventionen nicht erfolgreich zu etablieren. Gefordert wurde daher eine deutlichere Unterstützung durch politische und andere relevante Stakeholder, z. B. Krankenversicherungen und Vernetzung mit bzw. Einbettung dieses Themenfeldes in den öffentlichen Gesundheitsdienst.

Schlussfolgerung
Unsere Ergebnisse bestätigen aus Sicht von Expertinnen und Experten, dass die Förderung der Ernährungsgesundheit in den ersten 1000 Tagen sinnvoll und wichtig ist. Allerdings ist ein deutlicher Optimierungsbedarf hinsichtlich der Versorgungsstrukturen und der konkreten nachhaltigen Umsetzung von primärpräventiven Angeboten sowie niederschwelligen Zugängen für belastete Schwangere und Familien erkennbar.
Assessment of Amphora coffeaeformis and Scenedesmus dimorphus algae as immunostimulant agents on Biomphlaria alexandrina snails against Schistosoma mansoni
Authors: Mansour Shereen Mahfouz , Taha Rania Gamal , Youssef Alaa Ahmed 
Published: November 2022

AbstractSchistosoma mansoni is the main factor of human schistosomiasis which is responsible for high rates of mortality. Recently, the use of alternative biological control agents has gained importance in disease control because the intensive use of molluscicides is very harmful to human health and poses risks to the environment. In the present work, the potential effect of two freshwater algae, Amphora coffeaeformis and Scenedesmus obtusus, on the immune response of Biomphalaria alexandrina snails against infection with S. mansoni was investigated. Two different concentrations 1 and 2 g L− 1 from each dried algal material were tested on snails before exposure to miracidial infection by one day. The use of Amphora coffeaeformis has a greater immunostimulatory effect than Scendesmus obtusus at a low concentration of 1.0 g L− 1. The tested algae affected the snail’s hemocytes and its immune response to S. mansoni as evidenced by a significant decrease in infection rate and cercariae production. In addition, increasing in total hemocyte count, the formation of vacuoles, the appearance of several pseudopodia, and the formation of coarse granules in hemocytes of infected snails treated with A. coffeaeformis. Intense tissue reactions were also observed. In conclusion, it was confirmed that these algae can be used as an immunostimulant in the prevention and control of S. mansoni.
Immune Metabolism in TH2 Responses: New Opportunities to Improve Allergy Treatment — Disease-Specific Findings (Part 1)
Authors: Goretzki A. , Zimmermann J. , Rainer H. , Lin Y.-J. , Schülke Stefan 
Published: November 2022

Abstract

Purpose of Review
Recent high-level publications have shown an intricate connection between immune effector function and the metabolic state of the respective cells. In the last years, studies have begun analyzing the metabolic changes associated with allergies. As the first part of a two-article series, this review will briefly summarize the basics of immune metabolism and then focus on the recently published studies on metabolic changes observed in allergic patients.

Recent Findings
In the last 3 years, immune-metabolic research in allergology had a clear focus on asthma with some studies also reporting findings in food allergy and atopic dermatitis. Current results suggest asthma to be associated with a shift in cellular metabolism towards increased aerobic glycolysis (Warburg metabolism), while also displaying substantial changes in fatty acid- and amino acid metabolism (depending on investigated patient collective, asthma phenotype, and disease severity).

Summary
Understanding immune-metabolic changes in allergies will allow us to (I) better understand allergic disease pathology and (II) modulate immune-metabolic pathways to improve allergy treatment.
Physiological Roles of β-amyloid in Regulating Synaptic Function: Implications for AD Pathophysiology
Authors: Cai Wenwen , Li Linxi , Sang Shaoming , Pan Xiaoli , Zhong Chunjiu 
Published: November 2022

AbstractThe physiological functions of endogenous amyloid-β (Aβ), which plays important role in the pathology of Alzheimer's disease (AD), have not been paid enough attention. Here, we review the multiple physiological effects of Aβ, particularly in regulating synaptic transmission, and the possible mechanisms, in order to decipher the real characters of Aβ under both physiological and pathological conditions. Some worthy studies have shown that the deprivation of endogenous Aβ gives rise to synaptic dysfunction and cognitive deficiency, while the moderate elevation of this peptide enhances long term potentiation and leads to neuronal hyperexcitability. In this review, we provide a new view for understanding the role of Aβ in AD pathophysiology from the perspective of physiological meaning.
According to their Numbers: Assessing the Pew Research Center’s Estimate of 7.5 Million Jewish Americans
Authors: Tighe Elizabeth , Saxe Leonard , Parmer Daniel , Nussbaum Daniel , de Kramer Raquel Magidin 
Published: November 2022

AbstractThe Pew Research Center’s survey, Jewish Americans in 2020, was designed to provide estimates of the size of the US Jewish population, sociodemographic data on issues such as intermarriage, child-rearing, engagement in Jewish communal life, and a description of American Jewish attitudes. A sophisticated sample design was employed to ensure accurate and generalizable assessments of the population. Because Jews are a small sub-group and the US government does not collect census data on religious groups, creating estimates is a non-trivial task. The focus of this paper is on the validity of Pew’s estimate of 7.5 million US Jewish adults and children, 2.4% of the overall US population. The estimate is an important standalone indicator and is the basis for assessments of current Jewish attitudes and behavior. This paper considers the underlying construct of Jewish identity and its operationalization by Pew and evaluates the convergent validity of Pew’s findings. The efforts to define “who is a Jew” in sociodemographic surveys is described, and a set of methodological challenges to creating estimates are considered. The results of this review indicate that Pew’s criteria for inclusion in the population estimate comports with long-standing views of how to assess the Jewish population. Furthermore, Pew’s estimate of 7.5 million Jewish Americans is consistent with other recent demographic studies of the population. Their conclusions about a growing US Jewish population suggest a new narrative of American Jewish life that reflects the diversity of ways in which Jewish identity is expressed.