bluuebunny/crossref_metadata_2025_split huggingface dataset:
Critical evaluation of heat extraction temperature on soluble microbial products (SMP) and extracellular polymeric substances (EPS) quantification in wastewater processes
Authors: Lim Kahao , Parameswaran Prathap 
Published: March 2022

Abstract
While soluble microbial products (SMP) and extracellular polymeric substances (EPS) in wastewater bioprocesses have been widely studied, a lack of standard quantification procedures make it difficult to compare results between studies. This study investigated the effect of temperature on SMP and EPS profiles for biological nutrient removal (BNR) sludges and aerobic membrane bioreactor sludge by adapting the commonly used heat extraction and centrifugation scheme, followed by colorimetric quantification of the carbohydrate and protein fractions using the phenol-sulfuric acid (PS) and the bicinchoninic acid (BCA) methods, respectively. To overcome known inconsistencies in colorimetry, total carbon (TC), total nitrogen (TN), and fluorometry analyses were performed in tandem. SMP samples marginally benefitted from heat extraction, owing to their mostly soluble nature, while EPS profiles were greatly influenced by temperature. 60 °C appears to be a suitable general-purpose extraction temperature near the lysis threshold for the sludges tested. The PS method's misestimation due to lack of specificity was observed and contrasted by TC analyses, while the TN analyses corroborated the BCA assays. Fluorometry proved to be a sensitive and rapid analytical method that provided semi-quantitative information on SMP and EPS constituents, particularly its proteinaceous components, with positive implications for robust wastewater process control.
Investigating the Influence of ACTN3 R577X Polymorphism on Performance and Angular Kinematics Using Motion Capture Technology
Authors: Moe Thet Hnin , Wongveerakul Pongpanot , Saengsirisuwan Vitoon , Charoenpanich Nongnapas , Papadimitriou Ioannis 
Published: March 2022

Background:
The ACTN3 gene is known as the “sprinter gene” due to the increased frequency of the R allele of the gene in various cohorts of elite sprinters compared to the general population. In situ muscle fibers that express α-actinin-3 protein can produce more force than the muscle fibers that are α-actinin-3 deficient. In vivo analysis showed that individuals lacking the R variant of the gene (ACTN3 XX genotype) encoding α-actinin-3 demonstrated slower running times and lower peak knee torque at higher angular speeds (30–180 deg/s).

Aim:
The aim of this study is to investigate the influence of the ACTN3 gene on performance and angular kinematic characteristics by comparing ACTN3 RR+RX and ACTN3 XX individuals during explosive jumps and sprints using motion capture technology.

Methods:
The kinematic and force data were obtained using a Qualisys Track Manager (QTM) system, and DNA was isolated from white blood cells using standard procedures. The 291-bp PCR fragment was electrophoresed, visualized under UV light, and finally, digested with Hpy8 restriction endonuclease.

Results:
ACTN3 RR+RX individuals demonstrated statistically significant differences (P<0.05) in SJ, CMJ, and DJ jump height, greater mean values of peak vertical ground reaction force (PVGRF), increased angular velocity at the knee joint during the DJ jump, and greater torque production at higher angular speeds during 5-m sprints.

Conclusion:
In conclusion, our study allowed us to deepen our knowledge regarding the role of α-actinin-3 protein in human locomotion. The results indicate that the ACTN3 gene influences force production and certain angular kinematic characteristics during explosive jumps and sprints.
MEMAKSIMALKAN PERAN HUMAS DI LEMBAGA PENDIDIKAN ANAK USIA DINI
Authors: CAHYA NINGRUM EKA SAPTI 
Published: March 2022

Pendidikan yang diberikan kapada anak sebelum memasuki sekolah dasar merupakan salah satu alternatif yang harus dikembangkan dalam mempersiapkan anak menuju wajib belajar pendidikan dasar (9 tahun). Pendidikan dan perhatian terhadap anak pada usia 0-6 tahun sangat membantu perkembangan sosial, emosi, fisik, den kognitif anak. Perhatian terhadap pcrkembangan anak sejak dini sangat menentukan perkembangan anak secara menyeluruh. Sebelum memasuki pendidikan formal di bangku sekolah dasar, anak-anak perlu orientasi di bangku prasekolah. Persiapan ini bisa dilakukan melalui pendidikan formal (TK), nonformal (TPA KB), maupun informal (Keluarga). Pada sisi yang lain pemerintah melindungi hak anak mendapatkan layanan pendidikan. Ini terbukti pada pasal 28 Undang-undang Nomor 20 Tahun 2003 tentang Sistem Pendidikan Nasional yang mengatur PAUD, namun implementasinya di lapangan masih jauh dari apa yang diharapkan. Proporsi antara lembaga pendidikan anak usia dini di Indonesia didominasi oleh masyarakat, mencapai lebih dari 80% dengan variasi biaya pendidikan mulai dari yang sangat murah hingga yang sangat mahal. Penyebaran lembaga pendidikan anak usia dini di Jawa relatif merata, sedangkan di luar Jawa cenderung berada di daerah-daerah yang maju. Tingginya lembaga pendidikan anak usia dini yang difasilitasi oleh masyarakat menunjukkan dukungan berbagai dari pihak untuk pengembangan lembaga PAUD. Hubungan masyarakat dalam hal ini menjadi sebuah keharusan mengingat banyaknya kebutuhan pengembangan berkelanjutan. Keberhasilan hubungan dengan masyarakat pada lembaga pendidikan menentukan dukungan masyarakat dalam hal pendanaan maupun pemikiran dan perhatian untuk menjaga kelangsungan lembaga sekaligus meningkatkan kualitasnya.
Professional development and interpersonal communication: Influence on vocational teachers teaching performance
Authors: Ahmad Masduki , Rochimah Heni 
Published: March 2022

This research was conducted to see the impact of professional development and interpersonal communication on the teaching performance of vocational teachers in West Cikarang, West Java Province, Indonesia. The research method used is the survey method and data examination, namely multiple linear regression. The populace in this research was 119, with the Slovin formula with a 5% of significance level, then the research sample obtained was 92 vocational teachers. Data collection techniques using questionnaires and hypothesis testing using t-test and F-test. The outcome of this calculation shows that professional development and interpersonal communication on teacher teaching performance have simultaneous effects as indicated by the Fcount 34.453 Ftable 3.10 and the significance value 0.000 0.05. The large effect of professional development and interpersonal communication on teaching performance is shown throughout the coefficient determination of 0.443 or 44.3%, with the influence of professional development variables of 13.9% while interpersonal communication variables of 30.2%.
Curriculum and learning management: Integration of creative economy value to improve students’ life skill
Authors: Malaikosa Yes Matheos Lasarus , Widyadharma Andhika Putra , Pangestu Widya Trio 
Published: March 2022

The impact of the ASEAN economic community on the development of industry 4.0 is increasingly massive. The education system needs a new buzz to respond to the development of industry 4.0. The Indonesian government continues to make changes and developments in the field of education to prepare learners to become knowledgeable, capable, creative, independent, and responsible human beings. The research uses a qualitative approach, with data collection techniques through observation, interview, and one in the documentation of strengthening life skills with integrase creative economic value. In this study, researchers successfully interviewed the principal, teacher, student, and creative ruler of the alumni element of Grafika Desa Putera Vocational High School (SMK Grafika Desa Putera). The results showed that SMK Grafika Desa Putera integrates the important value of the creative economy for students in adaptive programs, local content, normative, productive, and self-development to produce productive, creative work. Vocational education aims to prepare graduates to be ready to work and innovate. The main purpose of this research is to know the content of the creative economy in shaping learners' life skills.
Discussions and Misinformation About Electronic Nicotine Delivery Systems and COVID-19: Qualitative Analysis of Twitter Content
Authors: Sidani Jaime E , Hoffman Beth , Colditz Jason B , Wolynn Riley , Hsiao Lily , Chu Kar-Hai , Rose Jason J , Shensa Ariel , Davis Esa , Primack Brian 
Published: March 2022

Background
Misinformation and conspiracy theories related to COVID-19 and electronic nicotine delivery systems (ENDS) are increasing. Some of this may stem from early reports suggesting a lower risk of severe COVID-19 in nicotine users. Additionally, a common conspiracy is that the e-cigarette or vaping product use–associated lung injury (EVALI) outbreak of 2019 was actually an early presentation of COVID-19. This may have important public health ramifications for both COVID-19 control and ENDS use.

Objective
Twitter is an ideal tool for analyzing real-time public discussions related to both ENDS and COVID-19. This study seeks to collect and classify Twitter messages (“tweets”) related to ENDS and COVID-19 to inform public health messaging.

Methods
Approximately 2.1 million tweets matching ENDS-related keywords were collected from March 1, 2020, through June 30, 2020, and were then filtered for COVID-19–related keywords, resulting in 67,321 original tweets. A 5% (n=3366) subsample was obtained for human coding using a systematically developed codebook. Tweets were coded for relevance to the topic and four overarching categories.

Results
A total of 1930 (57.3%) tweets were coded as relevant to the research topic. Half (n=1008, 52.2%) of these discussed a perceived association between ENDS use and COVID-19 susceptibility or severity, with 42.4% (n=818) suggesting that ENDS use is associated with worse COVID-19 symptoms. One-quarter (n=479, 24.8%) of tweets discussed the perceived similarity/dissimilarity of COVID-19 and EVALI, and 13.8% (n=266) discussed ENDS use behavior. Misinformation and conspiracy theories were present throughout all coding categories.

Conclusions
Discussions about ENDS use and COVID-19 on Twitter frequently highlight concerns about the susceptibility and severity of COVID-19 for ENDS users; however, many contain misinformation and conspiracy theories. Public health messaging should capitalize on these concerns and amplify accurate Twitter messaging.
MINAT MAHASISWA AKUNTANSI UNTRIM SEBAGAI PENGGUNA E-WALLET DENGAN MEMPERTIMBANGKAN PERSEPSI KEMANFAATAN, PERSEPSI KEMUDAHAN, DAN PERSEPSI KEPERCAYAAN
Authors: Afolo Salepa Celik Misrami , Dewi Ni Nyoman Sri Rahayu Trisna 
Published: March 2022

Penelitian ini bertujuan untuk mengetahui Pengaruh Persepsi Kemanfaatan (X1), Persepsi Kemudahan (X2), dan Persepsi Kepercayaan (X3), Terhadap Minat Mahasiswa Akuntansi Untrim sebagai Pengguna E-wallet (Y). Penelitian ini, menggunakan metode penelitian kuantitatif dengan jenis penelitian asosiatif. Populasi dalam penelitian ini yaitu mahasiswa Program Studi Akuntansi di Universitas Triatma Mulya angkatan 2017, 2018, dan 2019. Sampel diambil menggunakan metode purposive sampling dengan jumlah sampel 74 responden. Pada masa pandemi Covid-19 yang mana sesuai dengan kebijakan pemerintah, bahwa kegiatan pembelajaran dilaksanakan secara online, maka pengumpulan data dalam penelitian ini menggunakan kuesioner online melalui google form dan pengukurannya menggunakan skala likert. Dan metode analisis data yang digunakan adalah Uji Kualitas Data, Uji Asumsi Klasik, Analisis Regresi Berganda, Uji F (Kelayakan Model), dan Uji t. Hasil penelitian yang didapat dari analisis data menunjukan bahwa Persepsi Kemanfaatan, Persepsi Kemudahan, dan Persepsi Kepercayaan secara parsial berpengaruh positif dan signifikan terhadap Minat Pengguna E-wallet.
PENGARUH KOMPETENSI BAHASA INGGRIS TERHADAP KINERJA PEGAWAI
Authors: Putu Shinta Novianty  , Eka Ayu Purnama Lestari  , Komang Trisnadewi  
Published: March 2022

Banyak pendapat yang mengatakan bahwa kompetensi Bahasa Inggris menjadi modal dasar bagi SDM yang berkualitas. Penelitian ini dilakukan dengan tujuan untuk mengetahui seberapa besar pengaruh kompetensi Bahasa Inggris terhadap kinerja pegawai. Penelitian ini merupakan penelitian deskriptif dnegan pendekatan kualitatif dan kuantitatif. Subjek penelitian adalah para alumni STMIK STIKOM Indonesia yang sudah bekerja dengan ruang lingkup di bidang TI. Beberapa tahapan yang dilakukan pada penelitian ini mencakup perencanaan, pengumpulan data, analisis data, serta penyajian data. Perencanaan dilakukan dengan merumuskan pertanyaan dalam bentuk kuesioner. Selanjutnya pada tahapan pengumpulan data, kuesioner tersebut disebar melalui online kepada alumni STMIK STIKOM. Data yang telah diperoleh berupa jawaban kuesioner kemudia dianalisis. Proses analisis melalui beberpa tahpan mencakup membaca secara keseluruhan, mengelompokkan, kemudian meberikan penjelasan. Tahapan terakhir adalah menyajikannya dalam bentuk laporan. Hasilnya, kompetensi Bahasa Inggris memiliki pengaruh yang signifikan terdahap kinerja pegawai. Hal ini mengindikasikan bahwa pengaruh kompetensi terhadap kinerja pegawai adalah sebesar 67.0 %. Terkait kompetensi Bahasa, menyimak merupakan ketrampilan yang paling sering digunakan oleh pegawai bidang Teknologi Informasi.
Escala para medir actitudes de estudiantes de diseño gráfico hacia la investigación
Authors: Chamosa Sandoval María Esther 
Published: March 2022

El propósito del trabajo aquí reportado fue diseñar y validar una escala para medir las actitudes hacia el aprendizaje de metodologías de investigación y la producción de conocimiento entre estudiantes de diseño gráfico. Para ello, se utilizó un instrumento conformado de 45 ítems distribuidos en seis dimensiones relacionadas con la utilidad de la investigación para la profesión, valoración positiva y negativa hacia la investigación, entre otros. Para garantizar la confiabilidad del cuestionario, se le sometió a un proceso de validación por juicio de nueve expertos, se calculó la razón de validez de contenido mediante el estándar de Lawshe (1975) y la conveniencia global alcanzó un índice de validez de 0.85. Tras una primera aplicación piloto, se aplicó una segunda a 130 estudiantes y recién egresados de diseño, provenientes de dos instituciones públicas y dos privadas de la Ciudad de México y Toluca, y se obtuvo un alfa de Cronbach de 0.90, lo que confirma una confiabilidad muy alta. Los hallazgos obtenidos durante el segundo piloto ubicaron a los participantes en un nivel “neutro” hacia la investigación, un promedio de 3.53 para las universidades privadas y 3.64 para las homólogas públicas, esto es, por debajo del rango “medianamente positivo”, que requiere al menos cuatro puntos. Tras un análisis de género, se evidenció (con 20 décimas arriba) que las mujeres mostraron mejor actitud hacia la investigación que los varones y 75 % de los promedios más favorables fueron obtenidos por mujeres.
Pengembangan Desa Sendangsari dengan Pengolahan Potensi Desa dan Pendidikan Anak dengan Buku Ajar
Authors: Visnhu Bartolomeus Galih 
Published: March 2022

Pendidikan anak dan pengelolaan potensi desa merupakan dua faktor yang penting bagi penelitian di Desa Sendangsari. Komoditas pertanian singkong yang tinggi di Desa Sendangsari dirasa kurang diolah dengan baik sehingga Kelompok 99 berinovasi untuk memajukan komoditas singkong untuk meningkatkan nilai jual produk desa dengan sentuhan yang lebih sehat dan modern yaitu dengan mengembangkan pengelelolaan singkong menjadi kue brownies menggunakan alternatif gula sehat dengan buah pisang yang juga merupakan komoditas pertanian di Desa Sendangsari. Pendidikan anak diangkat dalam isu ini dikarenakan banyaknya sekolah jenjang PAUD dan SD yang ada pada desa ini. Pentingnya mengenalkan dasar-dasar pendidikan bagi anak-anak usia dini diharapkan dapat menjadi bekal bagi pendidikan di masa depan seperti mengenal angka, warna, benda, dan etika dalam kehidupan sehari-hari lewat buku ajar sederhana
Effects of Antihypertensive Drugs on Alveolar Bone Loss in Patients with Chronic Periodontitis: A Retrospective Study
Authors: Al-Bayaty FH , Ibrahim OE , William C , Khairuddin NA 
Published: March 2022

Objective: This retrospective study aims to evaluate the possible effects of antihypertensive drugs on alveolar bone loss in patients with chronic periodontitis. Methods: 50 patients on antihypertensive drugs selected as the experimental group and 50 patients with chronic periodontitis with no known systemic illnesses as control group were randomly selected as the study samples. Orthopantomographs were obtained, calibration and assessment of alveolar bone loss was performed by using the computer software program available in the faculty, through radiographic linear measurement procedure. Premolars, first and second molars of both maxilla and mandible were measured from the most apical point to the cementoenamel junction for mesial and distal aspects in the form of millimetres and percentile of the root length. Data was statistically analyzed using independent t-test and Analysis of Covariance in SPSS Version 23 with significance at P-value, p<0.05. Results: A total of 2428 sites were measured. Analysis has shown that there is significant difference in alveolar bone loss in experimental group and control group (p=0.002). Bone loss in the experimental group was less (16.28 ± 9.48) compared to the control group (22.66 ± 12.58). Within the experimental group, there was no significant difference for the duration of antihypertensive drug intake. However, the bone loss was more among the males (19.71 ± 11.22) than the females (12.99 ± 5.99). Conclusion: Antihypertensive drugs appear to have a positive effect on alveolar bone loss progression. Patients under these drugs exhibit lower levels of bone loss compared to those who are not.
It Starts at Home
Authors: Cooke Nicole A. , Warren Kellee E. , Brown Molly , Jackson Athena N. 
Published: March 2022

This interview features a conversation between a library and information science educator (Cooke) and three archival and special collections professionals with varying levels of experience in the field (Warren, Brown, and Jackson). Among the goals of this frank conversation is to highlight the lived experiences of practicing archivists and educators and discuss why it’s becoming increasingly important to talk about empathy, diversity, equity, and inclusion in greater context. As part of that context, we must discuss the need to continuously infuse these values into graduate education, professional development, research, writing, and peer mentoring. Espousing and implementing an ethics of care is an ongoing and necessary process and commitment - to ourselves, to the professions, and to our communities.
Pre-print first published online 10/04/2020
Radical Empathy in Peer Education
Authors: Winn Samantha R. 
Published: March 2022

Since 2015, I have provided a workshop on deconstructing whiteness through community narratives. Although the exercises, readings, and content changed to meet the needs of each host institution, all iterations of the workshop have aimed to build radical empathy through a combination of relational dialogue and storytelling. In this essay, I will recount the events and people who shaped this workshop over time, reflect on my experiences as an instructor and facilitator, and discuss various shortcomings of my approach.
Pre-print first published online 05/18/2021
Revisiting a Feminist Ethics of Care in Archives
Authors: Caswell Michelle , Cifor Marika 
Published: March 2022

In this featured commentary, Michelle Caswell and Marika Cifor revisit their article, “From Human Rights to Feminist Ethics: Radical Empathy in Archives”* and update its insights to reflect care work in our present time of crisis.
Pre-print first published online 06/11/2021

*Michelle Caswell and Marika Cifor, “From Human Rights to Feminist Ethics: Radical Empathy in Archives,” Archivaria 81 (Spring 2016): 23-43.
PIWI-interacting RNA (piRNA): a narrative review of its biogenesis, function, and emerging role in lung cancer
Authors: Mukherjee Pritha , Bhattacharjee Shamee , Mandal Deba Prasad 
Published: March 2022

Abstract
Cancer remains elusive in many aspects, especially in its causes and control. After protein profiling, genetic screening, and mutation studies, scientists now have turned their attention to epigenetic modulation. This new arena has brought to light the world of noncoding RNA (ncRNA). Although very complicated and often confusing, ncRNA domains are now among the most attractive molecular markers for epigenetic control of cancer. Long ncRNA and microRNA (miRNA) have been studied best among the noncoding genome and huge data have accumulated regarding their inhibitory and promoting effects in cancer. Another sector of ncRNAs is the world of PIWI-interacting RNAs (piRNAs). Initially discovered with the asymmetric division of germline stem cells in the Drosophila ovary, piRNAs have a unique capability to associate with mammalian proteins analogous to P-element induced wimpy testis (PIWI) in Drosophila and are capable of silencing transposons. After a brief introduction to its discovery timelines, the present narrative review covers the biogenesis, function, and role of piRNAs in lung cancer. The effects on lung cancer are highlighted under sections of cell proliferation, stemness maintenance, metastasis, and overall survival, and the review concludes with a discussion of recent discoveries of another class of small ncRNAs, the piRNA-like RNAs (piR-Ls).
Development and Validation of Bioanalytical Method for Determination of Nebivolol and Valsartan in Human Plasma by Using RP-HPLC
Authors: Kachave R. N. , Mundhe A. G. 
Published: March 2022

Abstract

Aim
Nebivolol and valsartan are used in the treatment of hypertension. So, this study was conducted for the purpose of determining bioavailability/bioequivalence of nebivolol and valsartan in human plasma.

Materials and Methods
The chromatographic separation was performed on Symmetry C18 (150 × 4.6 mm, 5 μm) column using 0.01 N potassium dihydrogen phosphate (pH 3.0):acetonitrile (60:40) as the mobile phase at a flow rate of 1.0 mL/min and a detector wavelength of 280 nm. The retention times of nebivolol and valsartan in plasma were found to be 3.1 and 4.3 min, respectively.

Results
The method was validated statistically and by recovery studies. The linearity concentration was acceptable in the range of 0.5–10 ng/mL for nebivolol and 400–8000 ng/mL for valsartan. The lower limits of quantification were 0.5 ng/mL for nebivolol and 400 ng/mL for valsartan, which reached the levels of both drugs possibly found in human plasma. Per cent recoveries were obtained as 97.78% and 98.11% for nebivolol and valsartan, respectively.

Conclusion
The proposed method is simple, rapid, accurate, precise and gives us knowledge about the pharmacokinetics and therapeutic drug monitoring in clinical laboratories.