bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refocusing cancer supportive care: a framework for integrated cancer care
Authors: Krishnasamy Meinir , Hyatt Amelia , Chung Holly , Gough Karla , Fitch Margaret 
Published: December 2022

Abstract
Objective

Cancer supportive care comprises an integrative field of multidisciplinary services necessary for people affected by cancer to manage the impact of their disease and treatment and achieve optimal health outcomes. The concept of supportive care, largely driven by Margaret Fitch’s seminal supportive care framework, was developed with the intent to provide health service planners with a conceptual platform to plan and deliver services. However, over time, this concept has been eroded, impacting implementation and practice of supportive care. This study therefore aimed to examine expert contemporary views of supportive care with the view to refocusing the definition and conceptual framework of cancer supportive care to enhance relevance to present-day cancer care.

Methods
A two-round online modified reactive Delphi survey was employed to achieve consensus regarding terminology to develop a contemporary conceptual framework. A listing of relevant cancer supportive care terms identified through a scoping review were presented for assessment by experts. Terms that achieved ≥ 75% expert agreement as ‘necessary’ were then assessed using Theory of Change (ToC) to develop consensus statements and a conceptual framework.

Results
A total of 55 experts in cancer control with experience in developing, advising on, delivering, or receiving supportive care in cancer took part in the Delphi surveys. Expert consensus assessed current terminology via Delphi round 1, with 124 terms deemed relevant and ‘necessary’ per pre-specified criteria. ToC was applied to consensus terms to develop three key statements of definition, and a comprehensive conceptual framework, which were presented for expert consensus review in Delphi round 2.

Conclusion
Finalised definitions and conceptual framework are strongly aligned with relevant international policy and advocacy documents, and strengthen focus on early identification, timely intervention, multidisciplinary collaboration, and end-to-end, cross-sector, cancer supportive care.
On the use of domain knowledge for process model repair
Authors: Revoredo Kate 
Published: December 2022

AbstractProcess models are important for supporting organizations in documenting, understanding and monitoring their business. When these process models become outdated, they need to be revised to accurately describe the new status quo of the processes in the organization. Process model repair techniques help at automatically revising the existing model from behavior traced in event logs. So far, such techniques have focused on identifying which parts of the model to change and how to change them, but they do not use knowledge from practitioners to inform the revision. As a consequence, fragments of the model may change in a way that defies existing regulations or represents outdated information that was wrongly considered from the event log. This paper uses concepts from theory revision to provide formal foundations for process model repair that exploits domain knowledge. Specifically, it conceptualizes (1) what are unchangeable fragments in the model and (2) the role that various traces in the event log should play when it comes to model repair. A scenario of use is presented that demonstrates the benefits of this conceptualization. The current state of existing process model repair techniques is compared against the proposed concepts. The results show that only two existing techniques partially consider the concepts presented in this paper for model repair.
Heterologous expression and functional characterization of Drosophila suzukii OR69a transcript variants unveiled response to kairomones and to a candidate pheromone
Authors: Cattaneo Alberto Maria , Witzgall Peter , Kwadha Charles A. , Becher Paul G. , Walker William B. 
Published: December 2022

AbstractDrosophila suzukii is a main pest of berries on all continents. Population control relies on insecticides and a current research challenge is to develop alternative strategies. Methods based on behavior-modifying semiochemicals are widely used against other horticultural insects, and the functional characterization of chemoreceptors facilitates the identification of active compounds. Following heterologous expression of single olfactory receptors (ORs) in ab3A olfactory sensory neurons of D. melanogaster, we screened three transcript variants from the OR69a-locus (DsuzOR69aA, DsuzOR69aB, DsuzOR69aC), demonstrating binding to two possible kairomones (3-octanol and R-carvone) and to a possible fly-emitted volatile compound [(Z)-4-nonenal], although with different pharmacological qualities. By coupling Gas Chromatography to SSR (GC-SSR), these ligands enhanced ab3A-spiking at nanogram-aliquots in a complementary fashion among the different OR69a-variants, and we identified another possible kairomone, methyl salicylate, as the most active and specific ligand for the sole DsuzOR69aB. In testing headspaces collected from D. suzukii females and from the fly-associated yeast Hanseniaspora uvarum we did not observe activation from female headspaces but activation from yeast headspaces. In situ hybridization analysis on D. suzukii antennae suggests unique expression of OR69a-subunits in specific neurons, and points toward co-expression within the same neurons. The OR69a-subunits of D. suzukii constitute cation channels, which binding suggests kairomone specificity, even if effects coexist for a complementary binding of (Z)-4-nonenal. Methyl salicylate is the most active ligand and is specific to the sole DsuzOR69aB, inspiring future investigation to validate potentials of this compound for D. suzukii control strategies.
Improved Selectivity in 7 T Digit Mapping Using VASO-CBV
Authors: de Oliveira Ícaro A. F. , Siero Jeroen C. W. , Dumoulin Serge O. , van der Zwaag Wietske 
Published: December 2022

AbstractFunctional magnetic resonance imaging (fMRI) at Ultra-high field (UHF, ≥ 7 T) benefits from significant gains in the BOLD contrast-to-noise ratio (CNR) and temporal signal-to-noise ratio (tSNR) compared to conventional field strengths (3 T). Although these improvements enabled researchers to study the human brain to unprecedented spatial resolution, the blood pooling effect reduces the spatial specificity of the widely-used gradient-echo BOLD acquisitions. In this context, vascular space occupancy (VASO-CBV) imaging may be advantageous since it is proposed to have a higher spatial specificity than BOLD. We hypothesized that the assumed higher specificity of VASO-CBV imaging would translate to reduced overlap in fine-scale digit representation maps compared to BOLD-based digit maps. We used sub-millimeter resolution VASO fMRI at 7 T to map VASO-CBV and BOLD responses simultaneously in the motor and somatosensory cortices during individual finger movement tasks. We assessed the cortical overlap in different ways, first by calculating similarity coefficient metrics (DICE and Jaccard) and second by calculating selectivity measures. In addition, we demonstrate a consistent topographical organization of the targeted digit representations (thumb-index-little finger) in the motor areas. We show that the VASO-CBV responses yielded less overlap between the digit clusters than BOLD, and other selectivity measures were higher for VASO-CBV too. In summary, these results were consistent across metrics and participants, confirming the higher spatial specificity of VASO-CBV compared to BOLD.
The Use of Children as a Tactic of Intimate Partner Violence and its Impact on Survivors’ Mental Health and Well-being Over Time
Authors: Sullivan Cris M. , Sprecher Mackenzie , Guerrero Mayra , Fernandez Aileen , Simmons Cortney 
Published: December 2022

Abstract
Purpose
This is the first study to longitudinally examine the mental health and well-being impacts on survivors when their abusive partners and ex-partners use their children as an abuse tactic against them.

Methods
The sample included two hundred seventy-seven homeless or unstably housed survivors of intimate partner violence (IPV). All were mothers of minor children. Participants were interviewed shortly after seeking services and again at 6-months, 12-months, 18-months, and 24-months. They were asked about abuse they had experienced in the past six months, including the ways children were used as a form of IPV. They were also asked about their current depression, anxiety, and PTSD symptoms, as well as quality of life.

Results
Many of the participants reported their abusive partners and ex-partners had used their children as a form of IPV to control or hurt them. Further, after controlling for other forms of abuse, use of the children significantly predicted increased anxiety, PTSD symptoms, and quality of life (but not depression) over time.

Conclusion
It is important to recognize the widespread use of children as a common and injurious form of IPV, and its impact on the mental health and well-being of survivors.
A Trilaminar-Thermosensitive Hydrogel Catalytic Reactor Capable of Single/Tandem Catalytic Switchable Ability
Authors: Pu Lei , Luo Gang , Zhu Maiyong , Shen Xiaojuan , Wei Wenjing , Li Songjun 
Published: December 2022

AbstractThe present endeavor is to develop a highly-intelligent catalytic reactor prototype which is able to autonomously adapt to the environment and provides an in-situ double-shift catalytic ability. By seeking inspiration from nature, this objective is achieved by developing a self-adaptive hydrogel catalytic reactor which held a catalytic trilaminar structure capable of reverse thermosensitive properties. With increasing temperatures, the catalytic tri-layers of this catalytic reactor would function in a sequential way (i.e., one negative temperature response layer, one support layer and one positive temperature response layer) and as a result, led to the single-tandem double-shift catalytic ability. This catalytic reactor individually presented single/tandem catalytic process at relatively low temperatures or high temperatures through the cooperative work of the three layers. In this way, this catalytic reactor showed the single-tandem controllable catalytic ability. The novel protocol not only provides a new solution to complicated catalytic processes but also inspires the further application of smart polymers in a broader spectrum of areas.
The Emergence of Habitual Ochre Use in Africa and its Significance for The Development of Ritual Behavior During The Middle Stone Age
Authors: Dapschauskas Rimtautas , Göden Matthias B. , Sommer Christian , Kandel Andrew W. 
Published: December 2022

AbstractOver the last two decades, red ochre has played a pivotal role in discussions about the cognitive and cultural evolution of early modern humans during the African Middle Stone Age. Given the importance of ochre for the scholarly debate about the emergence of ‘behavioral modernity’, the lack of long-term spatio-temporal analyses spanning large geographical areas represents a significant gap in knowledge. Here we take a continent-wide approach, rather than focusing on specific sites, regions or technocomplexes. We report the most comprehensive meta-analysis of ochre use to date, spanning Africa between 500 and 40 thousand years ago, to examine data from more than a hundred archaeological sites. Using methods based on time averaging, we identified three distinct phases of ochre use: the initial phase occurred from 500,000 to 330,000; the emergent phase from 330,000 to 160,000; and the habitual phase from 160,000 to 40,000 years ago. The number of sites with ochre increased with each subsequent phase. More importantly, the ratio of sites with ochre compared to those with only stone artifacts also followed this trend, indicating the increasing intensity of ochre use during the Middle Stone Age. While the geographical distribution expanded with time, the absolute number of ochre finds grew significantly as well, underlining the intensification of ochre use. We determine that ochre use established itself as a habitual cultural practice in southern, eastern and northern Africa starting about 160,000 years ago, when a third of archaeological sites contain ochre. We argue that this pattern is a likely material manifestation of intensifying ritual activity in early populations ofHomo sapiens. Such ritual behavior may have facilitated the demographic expansion of early modern humans, first within and eventually beyond the African continent. We discuss the implications of our findings on two models of ritual evolution, theFemale Cosmetic Coalitions Hypothesisand theEcological Stress Hypothesis,as well as a model about the emergence of complex cultural capacities, theEight-Grade Model for the Evolution and Expansion of Cultural Capacities.
From philosophical traditions to scientific developments: reconsidering the response to Brouwer’s intuitionism
Authors: Kish Bar-On Kati 
Published: December 2022

AbstractBrouwer’s intuitionistic program was an intriguing attempt to reform the foundations of mathematics that eventually did not prevail. The current paper offers a new perspective on the scientific community’s lack of reception to Brouwer’s intuitionism by considering it in light of Michael Friedman’s model of parallel transitions in philosophy and science, specifically focusing on Friedman’s story of Einstein’s theory of relativity. Such a juxtaposition raises onto the surface the differences between Brouwer’s and Einstein’s stories and suggests that contrary to Einstein’s story, the philosophical roots of Brouwer’s intuitionism cannot be traced to any previously established philosophical traditions. The paper concludes by showing how the intuitionistic inclinations of Hermann Weyl and Abraham Fraenkel serve as telling cases of how individuals are involved in setting in motion, adopting, and resisting framework transitions during periods of disagreement within a discipline.
UAV LiDAR Metrics for Monitoring Crop Height, Biomass and Nitrogen Uptake: A Case Study on a Winter Wheat Field Trial
Authors: Hütt Christoph , Bolten Andreas , Hüging Hubert , Bareth Georg 
Published: December 2022

AbstractEfficient monitoring of crop traits such as biomass and nitrogen uptake is essential for an optimal application of nitrogen fertilisers. However, currently available remote sensing approaches suffer from technical shortcomings, such as poor area efficiency, long postprocessing requirements and the inability to capture ground and canopy from a single acquisition. To overcome such shortcomings, LiDAR scanners mounted on unmanned aerial vehicles (UAV LiDAR) represent a promising sensor technology. To test the potential of this technology for crop monitoring, we used a RIEGL Mini-VUX-1 LiDAR scanner mounted on a DJI Matrice 600 pro UAV to acquire a point cloud from a winter wheat field trial. To analyse the UAV-derived LiDAR point cloud, we adopted LiDAR metrics, widely used for monitoring forests based on LiDAR data acquisition approaches. Of the 57 investigated UAV LiDAR metrics, the 95th percentile of the height of normalised LiDAR points was strongly correlated with manually measured crop heights (R2 = 0.88) and with crop heights derived by monitoring using a UAV system with optical imaging (R2 = 0.92). In addition, we applied existing models that employ crop height to approximate dry biomass (DBM) and nitrogen uptake. Analysis of 18 destructively sampled areas further demonstrated the high potential of the UAV LiDAR metrics for estimating crop traits. We found that the bincentile 60 and the 90th percentile of the reflectance best revealed the relevant characteristics of the vertical structure of the winter wheat plants to be used as proxies for nitrogen uptake and DBM. We conclude that UAV LiDAR metrics provide relevant characteristics not only of the vertical structure of winter wheat plants, but also of crops in general and are, therefore, promising proxies for monitoring crop traits, with potential use in the context of Precision Agriculture.
Free to choose or free to lose? Understanding individual attitudes toward paternalism
Authors: Lassen David Dreyer , Mahler Daniel 
Published: December 2022

AbstractIn the past decades, behavioral economics has credibly identified numerous decision-making biases leading people to make choices they would not have made if better informed about the long-term consequences of their actions. This has given rise to a new reason for government interventions: internalities. In contrast to traditional reasons for government intervention, such as redistribution and externalities, overcoming internalities often involves the use of paternalistic policies. We investigate theoretically and empirically the formation of attitudes toward paternalistic policies. Theoretically, we focus on the role of self-interest and distinguish between self-interest as construed for the rational decision-maker, self-interest when self-control problems are present, and self-interest when procedural or expressive elements, such as autonomy, matter. Empirically, we employ two novel data sets: a Danish survey on political opinion combined with administrative data on actual behavior and a large-scale cross-country survey to analyze attitudes toward paternalistic policies in the health and financial domains. We show that targets of paternalism are more opposed to paternalism than non-targets both in Denmark and across nine Western democracies and rely on our theoretical priors to explore mechanisms that can explain these attitudes.
Elections and Immigration Policy in Autocracy: Evidence from Russia and Kazakhstan
Authors: Joo Song Ha 
Published: December 2022

AbstractWhy do some authoritarian states adopt more restrictive immigration policies than others? Much of the existing literature focuses on the politics of immigration in democracies, despite the presence of large-scale immigration to autocracies. In this article, I argue that the level of electoral competition can be a key factor in immigration policymaking in electoral autocracies. Autocrats who face high levels of electoral competition tend to impose immigration restrictions as a way of mobilizing anti-outgroup sentiment and boosting their own popularity. I test this hypothesis by conducting comparative case studies on Russia and Kazakhstan, both of which are major immigrant-receiving autocracies. Based on the analysis of original data gathered from 11 months of fieldwork in the two countries, I find that the relatively high level of electoral competition in Russia in the 2010s facilitated increased immigration restrictions, while Kazakhstan depoliticized labour immigrants and enacted a de facto open immigration policy in the absence of electoral competition.
Observations and simulations of new snow density in the drifting snow-dominated environment of Antarctica
Authors: Wever Nander , Keenan Eric , Amory Charles , Lehning Michael , Sigmund Armin , Huwald Hendrik , Lenaerts Jan T. M. 
Published: December 2022

AbstractOwing to drifting snow processes, snow accumulation and surface density in polar environments are variable in space and time. We present new field data of manual measurements, repeat terrestrial laser scanning and snow micro-penetrometry from Dronning Maud Land, Antarctica, showing the density of new snow accumulations. We combine these data with published drifting snow mass flux observations, to evaluate the performance of the 1-D, detailed, physics-based snow cover model SNOWPACK in representing drifting snow and surface density. For two sites in East Antarctica with multiple years of data, we found a coefficient of determination for the simulated drifting snow ofr2= 0.42 andr2= 0.50, respectively. The field observations show the existence of low-density snow accumulations during low wind conditions. Successive high wind speed events generally erode these low-density layers while producing spatially variable erosion/deposition patterns with typical length scales of a few metres. We found that a model setup that is able to represent low-density snow accumulating during low wind speed conditions, as well as subsequent snow erosion and redeposition at higher densities during drifting snow events was mostly able to describe the observed temporal variability of surface density in the field.
Performance analysis of high-resolution ice-sheet simulations
Authors: Bueler Ed 
Published: December 2022

AbstractNumerical glacier and ice-sheet models compute evolving ice geometry and velocity fields using various stress-balance approximations and boundary conditions. At high spatial resolution, with horizontal mesh/grid resolutions of a few kilometers or smaller, these models usually require time steps shorter than climate-coupling time scales because they update ice thickness after each velocity solution. High-resolution performance is degraded by the stability restrictions of such explicit time-stepping. This short note, which considers the shallow ice approximation and Stokes models as stress-balance end members, clarifies the scaling of numerical model performance by quantifying simulation cost per model year in terms of mesh resolution and the number of degrees of freedom. The performance of current-generation explicit time-stepping models is assessed, and then compared to the prospective performance of implicit schemes. The main results highlight the key roles played by the algorithmic scaling of stress-balance solvers and coupled, implicit-step solvers.
Three Types of Science
Authors: Haas Michael 
Published: December 2022

Hollywood applauds Glendon Schubert's script for a possible soap opera in his pre-view of Approaches to the Study of Political Science. Stereotypic characters, miscasting of actors, words put in the mouths of fictitious persons, and maudlin grief are all present in his poignant ad hominen remarks, while a task which I regard as important — the development of a science of politics — is curiously overlooked by Mr. Schubert as the main purpose of the volume. And, in a manner similar to David Easton's eloquent 1969 presidential address, it is important to tune out Mr. Schubert's solipsistic One Man's Family and to discuss instead the real reasons for all the current fuss about postbehavioral options.My own view is that political science has achieved considerable maturity as a discipline in recognizing a fundamental symbiosis between three facets of science as the 1970's begin. At one level, a scientist may seek to describe an individual case, to calibrate measuring Instruments, and to engineer specific changes in the real world. At a second level a scientist can search for relationships between two or more variables across several cases in order to state generalizations that will serve as guides to the future and to cases as yet unexamined. Yet myriad generalizations do not cumulatively add up to higher and higher levels of scientific achievement until we consider a third facet of science, wherein one seeks analytical explanations for empirical findings and smooths out the idiosyncracies of particular research investigations into analytically parsimonious paradigms, models, and theories concerning how the world is put together. These three levels or types of science may be called clinical, empirical, and theoretical, respectively.
The Road to a Closed Forum: The Council's Membership Amendments
Authors: Knoll George H. 
Published: December 2022

I have just read with dismay, Council-proposed amendments to the proposed Constitution, PS, Winter, 1971, page 17, Article III.Apparently Council members feel only those who possess Doctor of Philosophy degrees are capable of knowledge and perceiving “truth”. This type of blatant elitism is difficult to believe or understand coming from those professing a concern for the minorities within APSA who have difficulty communicating and developing. I wonder if Council members feel restricting membership will increase the participation of the minorities.