bluuebunny/crossref_metadata_2025_split huggingface dataset:
FIRST REPORT OF BASAL ROT CAUSED BY Fusarium equiseti IN ONION CROPS FROM PUEBLA, MEXICO
Authors: Romero-Arenas Omar , Martínez-Salgado Saira Jazmin , Rivera Antonio , Huerta-Lara Manuel , Laug-García Beatriz , Villa-Ruano Nemesio 
Published: July 2022

<p><strong>Background</strong>: Species of the <em>Fusarium</em> genus are considered as devastating phytopathogens of onion crops around the world. <strong>Objective</strong>: This work aimed to know the causal agent of basal rot in onion crops from Puebla-México recorded in 2019. <strong>Methodology</strong>: The causal agent was isolated from diseased samples by tissue incubation in Potato Dextrose Agar medium (PDA) and the pathogenicity tests were done with the causal agent to demonstrate its involvement in basal rot. Monosporic cultures of the causal agent were generated for further microscopic characterization and molecular identification by Internal Transcribed Spacers ITS1 and ITS2. <strong>Results</strong>: According to the pathogenicity tests, the causal agent produced apical constriction and necrosis in the radicle and leaves accompanied by brown spots surrounded by yellowing as those observed in natural conditions. A 533 bp amplicon of the causative agent was obtained by partial amplification of the 5.8S rDNA gene. The sequence of the amplicon was compared with the sequences deposited in the database of the National Center for Biotechnology Information (NCBI) showing 100% homology with <em>Fusarium equiseti</em>. <strong>Implications</strong>: Our investigation reveals <em>F. equiseti</em> as an emergent causal agent of onion basal rot in crops from the community of “La Soledad” Puebla, México. <strong>Conclusion</strong>: Herein we report for the first time <em>F. equiseti</em> as a new phytopathogen of onion and further strategies should be considered for its control.</p>
NEUROPATHIC PAIN AS A CHALLENGING CLINICAL ENTITY IN OLDER ADULTS
Authors: Benlidayi Ilke Coskun 
Published: July 2022

Neuropathic pain is a challenging clinical entity in older adults. Certain clinical conditions such as diabetes mellitus, cerebrovascular diseases and infections may lead to neuropathic pain in the elderly. Recognizing neuropathic pain is essential for proper management. Neuropathic pain can be related to either peripheral or central conditions. A lesion or disease of the somatosensory system is required to define neuropathic pain. The assessment of neuropathic pain includes anamnesis, detailed physical examination, screening tools/questionnaires, quantitative sensory testing, and objective methods such as electroneuromyography, skin biopsy, and corneal confocal microscopy. The aim of this article was to review common neuropathic pain conditions in older adults and to provide an overview on the assessment tools.
Risk tolerance assessment in real assets investments: a scale validation in Brazil
Authors: Paula Lucas Davi Fernandes Lopes , Silva Luzia Cecília de Souza , Nobre Fábio Chaves , Nobre Liana Holanda Nepomuceno 
Published: July 2022

Purpose – Risk tolerance, understood as the willingness of accepting a certain amount of risk which was perceived in an uncertain scenario, has been broadly studied under the framework of personal financial. This research aims to validate a scale for investment risk tolerance when dealing with real assets, in a business context.
Design/methodology/approach – A survey was performed with 150 managers, directors, and entrepreneurs who make investment decisions regarding real assets in the commerce, industry, and service sectors. Exploratory factorial analysis was performed was applied to detect the dimensionality of Risk Tolerance construct.
Findings – Risk Tolerance in real assets investments is a construct composed by two dimensions, the first factor is related to the familiarity of the decision-maker with the company and its investments, and it was denominated comfort and security, following the original dimension from personal finance research. The second dimension refers to the unpredictability and the complexity of risky investments in real assets, and it was denominated ‘black box effect’. The last factor, however, did not achieve the standards of reliability and it need further research.
Determining factors of entrepreneurial intention: a study with entrepreneurs and potential entrepreneurs of the state of Acre
Authors: Brito Bárbara Alessandra Vieira de , Kuniyoshi Márcio Shoiti , Cappellozza Alexandre , Vieira Almir Martins 
Published: July 2022

Objectives - this article aimed to analyze, from the perspective of the Theory of Planned Behavior, the determining factors of the entrepreneurial intention of entrepreneurs and potential entrepreneurs of Acre.
Design / Methodology / Approach - The research covered graduates of the Empretec Seminar (SEBRAE), using the quantitative methodology of Structural Equation Modeling by Partial Least Square Structural Equation Modeling (PLS-SEM).
Results - Results showed that Attitude Towards Behavior is the construct that most positively influences the entrepreneurial intention, followed by the constructs of the subjective norms and the perception of control.
Limitations / implications of the research - The limitations of the study are related to the population because the list of participants includes only graduates of the Empretec Seminar, as well as the fact that it was not considered whether the individuals were temporally close to the triggering event.
Practical implications - Entrepreneurial intention is considered as the first step in the process of discovering and exploiting opportunities, which makes it a fundamental part of the understanding of entrepreneurship. The study contributes in diminishing the gap of theoretical and empirical studies on this subject in the Brazilian scenario.
Originality / value - The hypothesis that the need for achievement positively influences the entrepreneurial intention has not been accepted, which can occur due to the fact that the psychological characteristics of the entrepreneurs can undergo changes as the entrepreneur moves away from the motivating event of entrepreneurship.
Tibrone, un armosta poco intraprendente? Note su uno spartano in Asia
Authors: Tuci Paolo 
Published: July 2022

This paper focuses on the Spartan harmost Thibron, who led two expeditions to Asia in the first decade of the 4th century. It aims both to reconstruct the historical events, which are set in a context in which Sparta’s political action is characterised by both panhellenic and imperialistic traits, and the different representations of the harmost provided by the sources, in particular Xenophon and Diodorus.
Mapeamento Tecnológico de Processos Microbianos Aplicados na Biorremediação de Metais Pesados
Authors: Santos Sidnei Cerqueira dos , Castro Danielly Cristina Marques de , Assunção Palloma Sales de , Santos Thais Lopes dos , Quintella Cristina M. 
Published: July 2022

Este estudo objetivou avaliar o desenvolvimento tecnológico de produtos e processos de origem microbiana aplicados no tratamento de áreas contaminadas por metais pesados, por meio de um mapeamento tecnológico de patentes, uma ferramenta estratégica para identificar inovações tecnológicas. Para tal, foram realizadas buscas em bases de dados na plataforma do Instituto Nacional de Propriedade Industrial (INPI) e na do European Patent Office (EPO), utilizando-se uma combinação de palavras-chave e dois códigos da Classificação Internacional de Patentes (CIP). Foram selecionadas 247 patentes dos bancos de dados referidos. O maior número de depósito de patentes ocorreu nos anos de 2012 e 2013, sendo a China o maior depositante. As inovações tecnológicas mais depositadas foram relacionadas com a técnica de bioacumulação. Concluiu-se que a técnica de biorremediação está em ascensão, tornando-se uma interessante ferramenta para o tratamento de ambientes contaminados por metais pesados.
Is a weekly qualitative picket fence test sufficient? A proposed alternate EPID‐based weekly MLC QA program
Authors: Kalavagunta Chaitanya , Xu Huijun , Zhang Baoshe , Mossahebi Sina , MacFarlane Michael , Jiang Kai , Lee Sung‐Woo , Chen Shifeng , Sawant Amit , Gopal Arun , Yi ByongYong 
Published: July 2022

AbstractPurposeWell‐designed routine multileaf collimator (MLC) quality assurance (QA) is important to assure external‐beam radiation treatment delivery accuracy. This study evaluates the clinical necessity of a comprehensive weekly (C‐Weekly) MLC QA program compared to the American Association of Physics in Medicinerecommended weekly picket fence test (PF‐Weekly), based on our seven‐year experience with weekly MLC QA.MethodsThe C‐Weekly MLC QA program used in this study includes 5 tests to analyze: (1) absolute MLC leaf position; (2) interdigitation MLC leaf position; (3) picket fence MLC leaf positions at static gantry angle; (4) minimum leaf‐gap setting; and (5) volumetric‐modulated arc therapy delivery. A total of 20,226 QA images from 16,855 tests (3,371 tests × 5) for 11 linacs at 5 photon clinical sites from May 2014 to June 2021 were analyzed. Failure mode and effects analysis was performed with 5 failure modes related to the 5 tests. For each failure mode, a risk probability number (RPN) was calculated for a C‐Weekly and a PF‐Weekly MLC QA program. The probability of occurrence was evaluated from statistical analyses of the C‐Weekly MLC QA.ResultsThe total number of failures for these 16,855 tests was 143 (0.9%): 39 (27.3%) for absolute MLC leaf position, 13 (9.1%) for interdigitation position, 9 (6.3%) for static gantry picket fence, 2 (1.4%) for minimum leaf‐gap setting, and 80 (55.9%) for VMAT delivery. RPN scores for PF‐Weekly MLC QA ranged from 60 to 192 and from 48 to 96 for C‐Weekly MLC QA.ConclusionRPNs for the 5 failure modes of MLC QA tests were quantitatively determined and analyzed. A comprehensive weekly MLC QA is imperative to lower the RPNs of the 5 failure modes to the desired level (<125); those from the PF‐Weekly MLC QA program were found to be higher (>125). This supports the clinical necessity for comprehensive weekly MLC QA.
Ion‐Implantation in Titania‐Based Plasmonic Photo‐anodes: A Review
Authors: Vemula Sai Krishna , Raavi Sai Santosh Kumar 
Published: July 2022

AbstractThe metal‐oxide semiconductors exhibit remarkable optoelectronic properties and have immense implication in applications involving energy conversion, light emission, environmental remediation, etc. The presence of metal nanostructures in titanium dioxide (TiO2), zinc oxide metal‐oxide semiconductors have enhanced the photo‐activity, due to the plasmon resonances and are predominantly researched for organic and perovskite photovoltaics. Generally, the metal nanoparticle dopants are introduced by methods like sputtering, sol–gel, etc. However, compared with conventional doping methods, ion‐implantation technique is a purely physical process, and a high controllability and repeatability can be achieved. Here, the current status of synthesis of nanocomposites in TiO2‐based photo‐anodic applications by ion‐implantation method is reviewed, and there is no elaborate review on this topic. Finally, the future prospects of ion‐implantation technique for controlling the excitonic behavior in TiO2 are discussed.
Resilient iterative learning control for a class of discrete‐time nonlinear systems under hybrid attacks
Authors: Zhao Xuyang , Yin Yanling , Bu Xuhui 
Published: July 2022

AbstractThe security control problem for a class of unknown nonlinear systems is considered in this paper. For the nonlinear system running in the network environment, the measurement channel is subjected to hybrid attacks. Intermittent denial of service attacks and false data injection attacks are modeled as the hybrid attacks. According to the characteristics of the repetitive system, a resilient iterative learning control (ILC) algorithm under hybrid attacks is devised. Subsequently, the stability of the system is proved by mathematical derivation and theoretical analysis in the sense of mathematical expectation. The theoretical analysis results indicate that the resilient ILC algorithm can ensure the stability of the system, and the tracking error converges with the increased number of iterations. Finally, the validity of the algorithm is illustrated by numerical simulation and mobile robot simulation.
Model predictive control‐based longitudinal control for autonomous electric vehicle with changing mass
Authors: Wang Yijing , Deng Yuxiang , Wang Haoyu , Zuo Zhiqiang 
Published: July 2022

AbstractIn this paper, a longitudinal control strategy in terms of model predictive control (MPC) and mass estimator is investigated for an autonomous electric vehicle (AEV). A driving force table (DFT) is established to represent the relationship among throttle opening, speed, and driving force. A mass estimator is designed to obtain the actual mass of AEV. An MPC‐based controller with constraints is suggested to get the desired acceleration. Moreover, a feedforward controller is developed to calculate the throttle opening directly. Both the iterative feasibility and stability of the MPC are ensured. The experimental results are given to show the effectiveness of our strategy with mass estimator.
Autistic people outperform neurotypicals in a cartoon version of the Reading the Mind in the Eyes
Authors: Cross Liam , Piovesan Andrea , Atherton Gray 
Published: July 2022

AbstractPrior research suggests that while autistic people may demonstrate poorer facial emotion recognition when stimuli are human, these differences lessen when stimuli are anthropomorphic. To investigate this further, this work explores emotion recognition in autistic and neurotypical adults (n = 196). Groups were compared on a standard and a cartoon version of the Reading the Mind in the Eyes test. Results indicated that autistic individuals were not significantly different from neurotypicals on the standard version. However, autistic people outperformed neurotypicals on the cartoon version. The implications for these findings regarding emotion recognition deficits and the social motivation account of autism are discussed and support the view of socio‐cognitive differences rather than deficits in this population.Lay SummaryThe Reading the Mind in the Eyes test and a cartoon version were tested on autistic and neurotypical adults. Autistic adults were not significantly different on the original test compared to neurotypicals, but they outperformed neurotypical adults on the cartoon version.
The meanings, risk factors and consequences of religious extremism: The perceptions of Islamic education teachers from Israel
Authors: Saada Najwan 
Published: July 2022

AbstractThis multiple case study examines the attitudes of 14 Islamic education teachers from Israel towards the meaning, causes and consequences of religious extremism among students in their Arab and Muslim‐majority middle and high schools. These teachers define religious extremism as belief in absolute religious truth, inflexibility in religious interpretation, or strict adherence to Islamic teachings. In addition, the teachers distinguish the personal (adolescence, family problems and psychosocial needs), religious (unquestioned following of extremist imams or religion scholars; adopting of selective, literal and decontextualised readings of the religious text; influence of partisan teachers) and socio‐political factors (students' feelings of fear and anger towards Israel and its unjust and oppressive role in the Palestinian–Israeli conflict) that push students towards religious extremism. Religious extremism, the teachers conclude, may lead to hatred or violence against followers of other religions, antagonism between Muslims and Jews in Israel, increased Islamophobia in Western societies, the rejection of Islam, the oppression of female students and reduced student achievement and diminished future prospects.
The effect of compatibility of Aconiti Radix and honey on the pharmacokinetics of five Aconitum alkaloids in rat plasma
Authors: Wu Jiaofeng , Duan Rong , Deng Haoran , Li Lele , Zhao Yunli , Yu Zhiguo 
Published: July 2022

AbstractAconiti Radix [Chuanwu (CW)] is widely used to treat chronic and intractable diseases due to its remarkable curative effect. CW has been combined with honey for thousands of years to reduce toxicity and enhance efficacy. This study first determined the compatibility mechanism of CW with honey using a comparative pharmacokinetic concept. We developed and validated a simple, sensitive, specific, and accurate UHPLC–MS/MS method to simultaneously determine five Aconitum alkaloids in rat plasma after the oral administration of CW decoction and CW–honey concentrated solution. Pharmacokinetic parameters were significantly different between the two groups (P < 0.01 and P < 0.05). Compared with the CW group, Cmax and AUC0 → t decreased in the CW–honey group for three diester‐diterpenoid alkaloids (hypaconitine, mesaconitine, and aconitine); Tmax and T1/2 were prolonged. However, Cmax and AUC0 → t increased in the CW–honey group for two monoester‐diterpenoid alkaloids (benzoylaconine and benzoylmesaconine); Tmax was shortened, and T1/2 was prolonged. These findings suggest that honey affected the pharmacokinetic behaviors of five Aconitum alkaloids. We speculate that the detoxification and synergism of honey might result from reducing the toxicity of diester‐diterpenoid alkaloids and promoting the biological activity of monoester‐diterpenoid alkaloids in vivo. This study provides a theoretical basis for the clinical use of CW combined with honey.
Green innovation and enterprise reputation value
Authors: Chen Zhongfei , Hao Xinyue , Chen Fanglin 
Published: July 2022

AbstractUsing the data of Chinese listed enterprises in 2007–2020, we investigate the relationship between green innovation (GI) and enterprise reputation via OLS regression, IV‐Lasso, and random forest. Findings show that GI can improve enterprise reputation, and it has a significant positive lag effect. Additionally, we compare the different effects of green patent applications and approved green patents. A possible mechanism is that GI reduces the pollution emission of enterprises. GI also performs better in improving the reputation of coastal enterprises, state‐owned enterprises and large‐scale enterprises, and old enterprises. Our finding on the causal relationship between GI and enterprise reputation is of great significance in further understanding the practical value of GI activities, and it has certain reference value for the policy formulation of governments and decision making of enterprises.
Localization of the nerves innervating the pelvic floor muscles: An application to pelvic pain treatment
Authors: Hu Xiangnan , Hu Shuangjiang , Wang Meng , Xiong Wei , Yang Shengbo 
Published: July 2022

AbstractThe aim of this study was to achieve accurate localization of the body surface position and depth of the center of the intramuscular nerve dense region (CINDR) of the pelvic floor muscles and to establish a target site for treating pelvic floor muscle spasm or weakness. Thirty‐six adult cadavers were studied in the prone position. To locate the CINDR of the levator ani and coccygeus muscles, horizontal (H) and longitudinal (L) reference lines were used. Sihler's staining revealed the intramuscular nerve dense region of the pelvic floor muscles. The CINDR was labeled with barium sulfate and spiral computed tomography scanning, and three‐dimensional reconstructions were obtained. The anterior and posterior CINDR projection points (P and P′), the position of point P projected on to the H and L lines (PH and PL), and the CINDR depth were determined using the Syngo system. The PH of the CINDR of the levator ani and the coccygeus muscle were located at (24.73 ± 0.17)% and (15.93 ± 0.31)% of the H line, respectively. The PL were located at (84.30 ± 2.47)% and (6.76 ± 0.93)% of the L line. The puncture depth of the levator ani muscle was located at (5.56 ± 0.53) cm, and the depth of the coccygeus muscle at (22.08 ± 2.11)% of the PP' line. The body surface position and depth of the CINDR of the pelvic floor muscles were conducive to locating the target more efficiently and enhancing the efficacy of botulinum toxin A injection for treating pelvic floor muscle spasm and weakness with electrical stimulation or biofeedback.
ANKHD1 contributes to the malignant phenotype of triple‐negative breast cancer cells
Authors: de Almeida Bruna O. , de Almeida Larissa C. , Costa‐Lotufo Leticia V. , Machado‐Neto João A. 
Published: July 2022

AbstractAnkyrin repeat and KH domain‐containing protein 1, ANKHD1, has been identified as a regulator of signaling pathways and cellular processes of relevance in carcinogenesis. However, the role of ANKHD1 in breast cancer remains unclear. The aim of the present study was to characterize the expression pattern and involvement of ANKHD1 in the malignant phenotype of breast cancer cell lines and to investigate the clinical relevance of ANKHD1 in a breast cancer context. Gene and protein expressions were assessed in the cell lines by quantitative reverse transcription PCR and Western blot analysis, respectively, and ANKHD1 silencing through siRNA transfection was conducted for further in vitro functional assays. The expression of ANKHD1 was identified in non‐tumorigenic breast epithelium and breast cancer cell lines, but differences in cellular localization were found among the neoplasia subtypes. ANKHD1 silencing reduced the viability, clonogenicity, and migration of triple‐negative breast cancer (TNBC) cells. Bioinformatics analyses demonstrated that patients with triple‐negative basal‐like 2 and mesenchymal breast cancer subtypes had high ANKHD1 expression associated with poor recurrence‐free survival. Therefore, these data indicate that ANKHD1 relevance in breast cancer varies among its subtypes, indicating the importance of ANKHD1 in TNBC.
LMCD1 facilitates the induction of pluripotency via cell proliferation, metabolism, and epithelial‐mesenchymal transition
Authors: Ye Zhikai , Chen Ge , Hou Cuicui , Jiang Zhenlong , Wang Erkang , Wang Jin 
Published: July 2022

AbstractSomatic cell reprogramming was achieved by lentivirus mediated overexpression of four transcription factors called OSKM: OCT3/4, SOX2, KLF4, and c‐MYC but it was not very efficient. Here, we reported that the transcription factor, LMCD1 (LIM and cysteine rich domains 1) together with OSKM can induce reprogramming of human dermal fibroblasts into induced pluripotent stem cells (iPSCs) more efficiently than OSKM alone. At the same time, the number of iPSCs clones were reduced when we knocked down LMCD1. Further study showed that LMCD1 can enhance the cell proliferation, the glycolytic capability, the epithelial‐mesenchymal transition (EMT), and reduce the epigenetic barrier by upregulating epigenetic factors (EZH2, WDR5, BMI1, and KDM2B) in the early stage of reprogramming, making the cells more accessible to gain pluripotency. Additional research suggested that LMCD1 can not only inhibit the developmental gene GATA6, but also promote multiple signaling pathways, such as AKT and glycolysis, which are closely related to reprogramming efficiency. Therefore, we identified the novel function of the transcription factor LMCD1, which reduces the barriers of the reprogramming from somatic to pluripotent cells in several ways in the early stage of reprogramming.