bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding the pivotal roles of ACE2 in SARS-CoV-2 infection: from structure/function to therapeutic implication
Authors: Pouremamali Amir , Babaei Abouzar , Malekshahi Somayeh Shatizadeh , Abbasi Ardeshir , Rafiee Nastaran 
Published: June 2022

AbstractIn December 2019, a novel respiratory tract infection, from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was detected in China that rapidly spread around the world. This virus possesses spike (S) glycoproteins on the surface of mature virions, like other members of coronaviridae. The S glycoprotein is a crucial viral protein for binding, fusion, and entry into the target cells. Binding the receptor-binding domain (RBD) of S protein to angiotensin-converting enzyme 2 (ACE 2), a cell-surface receptor, mediates virus entry into cells; thus, understanding the basics of ACE2 and S protein, their interactions, and ACE2 targeting could be a potent priority for inhibition of virus infection. This review presents current knowledge of the SARS-CoV-2 basics and entry mechanism, structure and organ distribution of ACE2, and also its function in SARS-CoV-2 entry and pathogenesis. Furthermore, it highlights ACE2 targeting by recombinant ACE2 (rACE2), ACE2 activators, ACE inhibitor, and angiotensin II (Ang II) receptor blocker to control the SARS-CoV-2 infection.
“I See You”
Authors: Fang Karen 
Published: June 2022

Abstract
In the global outpouring during the 2020 racial justice protests and coverage of pandemic-related anti-Asian hate, modest forms of engagement such as reading and viewing lists were often suggested as means of fostering sympathy and understanding. This essay argues that combating contemporary Asian American hate requires a more explicit focus on countering invisibility. This objective, necessitated by the ways in which ethnic Asians have been systematically elided and rendered as foreign throughout US history, should focus exclusively on educating Americans about Chinese Exclusion and other facts of America's systemic racism against ethnic Asians. Such an approach acknowledges the very different modes of racialized surveillance by which Asian Americans have historically been othered.
Orientalism and Wellness in the United States
Authors: Putcha Rumya S. 
Published: June 2022

Abstract
This article explores how consumer practices tether Orientalism to wellness. Relying on ethnographic research, the author uncovers how racialization and racialized expressions of gender are produced by and through performative and discursive practices of wellness. Such practices, which are also sometimes described as mindfulness techniques, encourage participants to understand wellness as a state of mind wherein if a person mirrors the behavior or speech of what qualifies as wellness, then they will also become well themselves. Drawing on methods from critical consumer studies as well as critical race feminist theory, the author argues that contemporary wellness practices expose somatic, rather than literary, forms of Orientalism.
Grief, Translation, and the “Asian American Woman” in Hong Kong
Authors: Ting Grace En-Yi 
Published: June 2022

Abstract
This article draws on Judith Butler's theories of violence and grief in order to outline a self-reflexive narrative of teaching and speaking about the Atlanta shootings of March 2021 as a queer and feminist studies scholar of Japanese studies in Hong Kong. The article briefly explains how teaching about this occurrence of anti-Asian violence in East Asia might lead to important discussions of multiple imperialisms within/around Asia, while providing background on the broader potential of Asian American studies for pedagogical contexts within Asia. However, through a description of the author's own coming into being as a racialized, gendered subject in the act of teaching about the Atlanta shootings in Hong Kong, the focus is on a highly particular account of how grief and vulnerability might offer forms of political solidarity that are not defined by roles as distinct subjects belonging to recognizable groups and communities.
A mixed-methods study on the design of Artificial Intelligence and data science-based strategies to inform public health responses to COVID-19 in different local health ecosystems: A study protocol for COLEV
Authors: González-Uribe Catalina , Yañez Nicolás , Onshuus Niño Alf , Velasco Nubia , Cordovez Juan Manuel , Santos-Vega Mauricio , Niño-Machado Natalia , Burbano Andres , Forbes Angus , Amaya Guio Ciro Alberto , Turner Simon , Higuera-Mendieta Diana , Martínez-Cabezas Sandra 
Published: June 2022

Background: Artificial Intelligence (AI) and data science research are promising tools to better inform public policy and public health responses, promoting automation and affordability. During the COVID-19 pandemic, AI has been an aid to forecast outbreak spread globally. The overall aim of the study is to contribute to the ongoing public health, socioeconomic, and communication challenges caused by COVID-19. Protocol: COLEV is a five-pronged interdisciplinary mixed methods project based on AI and data science from an inclusive perspective of age and gender to develop, implement, and communicate useful evidence for COVID-19-related response and recovery in Colombia. The first objective is identification of stakeholders’ preferences, needs, and their use of AI and data science relative to other forms of evidence. The second objective will develop locally relevant mathematical models that will shed light on the possible impact, trajectories, geographical spread, and uncertainties of disease progression as well as risk assessment. The third objective focuses on estimating the effect of COVID-19 on other diseases, gender disparities and health system saturation. The fourth objective aims to analyze popular social networks to identify health-related trending interest and users that act as ‘super spreaders’ for information and misinformation. Finally, the fifth objective, aims at designing disruptive cross-media communication strategies to confront mis- and dis-information around COVID-19. To understand stakeholders’ perspectives, we will use semi-structured interviews and ethnographic work. Daily cases and deaths of COVID-19 reported from the National Surveillance System (INS) of Colombia will be used for quantitative analysis, and data regarding the online conversation will be obtained from Facebook and Twitter. Conclusions: COLEV intends to facilitate the dialogue between academia and health policymakers. The results of COLEV will inform on the responsible, safe and ethical use of AI and data science for decision-making in the context of sanitary emergencies in deeply unequal settings.
The acceptability and side effects of COVID-19 vaccine among health care workers in Nigeria: a cross-sectional study
Authors: Ilori Oluwatosin Ruth , Ilori Oluwatosin Stephen , Oluwatobi Awodutire Phillip , Ige Olabisi Roseline , Idowu Adesanmi B , Balogun Oluwafemi Samson , Lawal Olamide Idris 
Published: June 2022

Background: The COVID-19 pandemic is global public health crisis. Mass vaccination, until herd immunity is achieved, is one of the most effective ways of combating the deadly infectious virus. The disposition of health workers towards the AstraZeneca vaccine will most likely determine if other members of the community will be willing to get vaccinated or not. Thus, the purpose of this study is to determine the attitudes of healthcare workers to the COVID-19 vaccine, as well as determine the various side effects experienced by those who have already been vaccinated. Method: Frequency tables were created, and Chi-square was used to determine the relationship between respondents' socio-demographic characteristics, as well as their acceptance or rejection of the COVID-19 vaccine and attitude towards it. Using IBM SPSS Statistics for Windows, version 22.0, multinominal logistic regression was used to determine the key factors which influenced respondents’ decision to have the vaccine. Result: There was a statistically significant relationship between the cadre of health care workers, their tribe, and their involvement in the care of COVID-19 patients and their attitude towards the vaccine. Conclusion: Previous involvement in the care of COVID-19 patients is one of the most important determinants of health care workers' acceptance of the COVID-19 vaccine. Most respondents were positive about the vaccine; however, the fear of side effects was the primary reason why those who were yet to be vaccinated, do not plan to do so. The most common side effect reported by those who had already been vaccinated, was pain at the injection site. Public awareness of the vaccine and its benefits should be increased, and the vaccine should be made available in all health care facilities.
Contribution of the Big Five Personality Factors in predicting psychological hardiness among counselors working in providing psychosocial support for refugees in Jordan
Authors: Almahaireh Abdallah , AlKhawaldeh Mohammad , Salem Hussein 
Published: June 2022

Aim of the studyThe study aimed to identify the level of psychological hardiness and the big five factors of the dominant personality,and to reveal the contribution of those factors in predicting psychological hardiness among counselors working in providing psychosocial support to refugees in Jordan.Subject or material and methodsThe study sample consisted of (110) counselors, they were chosen by the purposive method. The researchers used a questionnaire as the study instrument that consisted of a sixty item of the big five personality factors scale and a twenty-six-item Psychological Hardiness scaleResultsThe results of the study showed the level of psychological hardiness was at a high level. The big five factors of dominant personality among the psychological counselors are in order: conscientiousness, openness, extraversion, agreeableness, all of them at a medium level, then neuroticism at a low level. The results also showed that the big five personality factors explained (48.3%) as a statistically significant predictor of counselor’s psychological hardiness.DiscussionThere is an existence of a statistically significant of the big five personality factors in predicting psychological hardiness among psychological counselors working in providing psychosocial support services to refugees and it is consistent with the results of the various studies of different and special society categories.ConclusionsOrganizations working with Refugees as the Institute for Family Health, the Center for Rehabilitation of Victims of Torture, the Child Protection Foundation, and the Society JRC for the rehabilitation of refugees, must invest the personal factors that characterize the counselors in improving their effectiveness in providing services and psychological support.
C-Reactive protein and Neutrophil lymphocyte ratio in Depressive disorder: a hospital based cross sectional study
Authors: B.M Uma , Bondade Swapna , Puthane Krishnaji Rao Sunil 
Published: June 2022

Aim of the studyTo evaluate High sensitive C-reactive Protein (Hs CRP) and neutrophil lymphocyte ratio (NLR) in patients with Depression and to compare HsCRP and NLR in Major Depressive disorder (MDD) and Recurrent depressive disorder (RDD)Subject or material and methodsThis was a hospital-based case control study conducted in year 2019 for 3 months duration. Ninety eight patients with Depressive disorder and 50 healthy controls were included. HAM-D, HsCRP and NLR was assessed for all subjects.ResultsHsCRP and NLR was more in patients with Depression than in controls and this was statistically significant. HsCRP and NLR was more in RDD compared to MDD. Both HsCRP, NLR were positively correlated with age, duration of illness, number of depressive episodes and HAMD scores. The odds of suicidal ideas in depressive patients was more with increase in HsCRP and NLR.DiscussionTo the best of our knowledge, this is the first study to compare inflammatory parameters in MDD and RDD. In our study, CRP and NLR were more in RDD compared to MDD. This could be explained by immune dysregulation and chronic inflammation in RDD. Resistance to antidepressant therapy, and relapse of depression causes an activation of inflammatory response. In the present study, we observed an association between suicidal ideas and CRP, NLR.ConclusionsInflammation plays a significant role in depression as indicated by elevated HsCRP and NLR. These parameters help to assess suicidal risk. A futuristic study can be taken up to assess the effect of antidepressants on their levels.
A 45-year follow-up study of juvenile schizophrenia. Part III: clinical picture and effect of the first hospitalization in the context of disease course and long-term social functioning of patients
Authors: Ślosarczyk Mariusz , Ślosarczyk Katarzyna , Ślosarczyk Mariusz 
Published: June 2022

Cel pracyW literaturze przedmiotu rzadko spotyka się badania nad predyktorami przebiegu schizofrenii młodzieńczej, zwłaszcza oparte na danych pochodzących z długoterminowych katamnez. W naszej analizie badamy zależności pomiędzy obrazem i efektem klinicznym pierwszej hospitalizacji a wskaźnikami klinicznymi i społecznymi przebiegu choroby.Metoda69 pacjentów hospitalizowanych w wieku średnio 16 lat (punkt 0) z powodu schizofrenii (rediagnozowanej retrospektywnie wg kryteriów ICD-10) i powtórnie zbadanych w 5 lat później (punkt 1 – badanie osobiste dotyczyło 41 osób) zostało po raz kolejny poddanych ocenie pod kątem parametrów klinicznych i społecznych w 45 lat po wyjściowej hospitalizacji (punkt 2 – badanie osobiste dotyczyło 21 osób).WynikiObraz kliniczny pierwszego epizodu schizofrenii w zakresie objawów autyzmu, apatii i abulii, objawów rozszczepiennych, formalnych zaburzeń myślenia, objawów katatonicznych, objawów hebefrenicznych, urojeń, omamów oraz sumarycznego nasilenia całej schizofreniczne psychopatologii, a także efekt pierwszej hospitalizacji (mierzony poziomem poprawy, wglądu oraz zdolności relacyjnych) ujawniły liczne i różnorodne korelacje zarówno z obrazem objawowym i klinicznym przebiegiem schizofrenii, jak i odległym funkcjonowaniem społecznym badanych. Zmiennymi o największym znaczeniu rokowniczym okazały się wyjściowy autyzm oraz poziom poprawy klinicznej, wglądu i zdolności do tworzenia relacji mierzone na końcu pierwszej hospitalizacji.WnioskiObjawy negatywne podczas pierwszego epizodu schizofrenii oraz jakość poprawy w obszarach objawów, wglądu chorobowego i zdolności do tworzenia związków osiągniętej podczas pierwszego pobytu szpitalnego okazały się istotnymi czynnikami prognostycznymi w schizofrenii młodzieńczej.
Evaluation of the relationship between some mental state parameters and the quality of life in patients with allergic diseases.
Authors: Badura Brzoza Karina , Piegza Magdalena , Błachut Michał , Gorczyca Piotr , Brzoza Zenon 
Published: June 2022

Cel pracyCelem pracy była ocena związku objawów depresji, poziomu poczucia koherencji z jakością życia pacjentów z chorobami alergicznymi.MetodaW badaniu udział wzięło 50 chorych na astmę oskrzelową, 72 chorych na sezonowy alergiczny nieżyt nosa, oraz 48 chorych na atopowe zapalenie skóry. Grupę kontrolną stanowiło 50 zdrowych ochotników. W ocenie depresji użyto skali BDI, w ocenie poczucia koherencji skali SOC-29, w ocenie jakości życia skali SF-36.WynikiŚrednie wartości nasilenia depresji były w grupie chorych na alergiczny nieżyt nosa oraz chorych na atopowe zapalenie skóry wyższe niż w grupie kontrolnej. Chorzy w tej ostatniej grupie wykazywali ponadto wyższe niż chorzy na astmę oskrzelową wartości nasilenia depresji. We wszystkich grupach badanych wykazano, w porównaniu z osobami zdrowymi, znamiennie statystycznie niższe wartości parametrów całkowitego poczucia koherencji. Nie zaobserwowano różnic w wartościach poczucia koherencji, w porównaniach między grupami badanymi. We wszystkich grupach chorych, w porównaniu z grupą kontrolną, obserwowano niższe wartości w zakresie funkcjonowania fizycznego (PCS) skali jakości życia.
Nasilenie objawów depresji we wszystkich grupach wykazywało negatywne korelacje z parametrami jakości życia oraz poczuciem koherencji. Parametry poczucia koherencji korelowały ponadto negatywnie z parametrami funkcjonowania w wymiarze psychicznym (MCS) skali jakości życia.Wnioski1.	Pacjenci z atopowym zapaleniem skóry wykazali największe nasilenia objawu depresyjnych.
2.	Chorzy na sezonowy alergiczny nieżyt nosa wykazują lepszą jakości życia niż chorzy na przewlekłą astmę oskrzelową i chorzy na atopowe zapalenie skóry
3.	Niskie poczucie koherencji u osób cierpiących na atopowe choroby alergiczne oraz występowaniem objawów depresji może pogarszać jakością życia.
The specificity and the affective sign of autobiographical memories in individuals with depressive disorders and alcohol use disorder
Authors: Rybak-Korneluk Anna , Wichowicz Hubert , Stankiewicz-Wróblewska Joanna , Żuk Krzysztof , Dziurkowski Maciej , Adrych Krystian 
Published: June 2022

Cel pracyZaburzenia psychiczne mogą zakłócać Pamięć Autobiograficzną (PA). Przykładem są nadmiernie generalne wspomnienia tj. pozbawione detali wspomnienia o uogólnionym i semantycznym charakterze. Głównym celem badania była ocena funkcjonowania PA u pacjentów z epizodem depresji (DEP) i zespołem zależności alkoholowej (ALK).MetodaBadanie porównało dwie grupy badane: hospitalizowanych pacjentów z DEP i ALK (grupy badane) oraz dwie grupy kontrolne: osoby hospitalizowane z powodu chorób gastroenterologicznych (CON) i zdrowe (PAN) (N = 39 dla każdej; średnia wieku: 46,0 ± 13,6, brak różnic).
Testem Pamięci Autobiograficznej sprawdzono specyficzność PA. Uczestnicy ocenili wspomnienia pod względem wyrazistości, intensywności i znaku afektywnego.WynikiGrupy badane przywołały mniej specyficznych wspomnień niż kontrolne (p < ,001 dla: wszystkich, pozytywnych i negatywnych słów bodźcowych), z najniższymi wynikami w DEP. Grupy kliniczne przywołały również więcej negatywnych i mniej pozytywnych wspomnień (p < ,001) niż kontrolne; z deficytem pozytywnych wspomnień w DEP i nadmiarem negatywnych w ALK.
Analiza odpowiedzi niespecyficznych ujawniła, że grupa ALK przywoływała więcej wspomnień „rozszerzonych” niż CON (p < ,005) i „kategorycznych” niż grupy kontrolne (p < ,05). Grupa DEP przywoływała więcej „skojarzeń semantycznych” niż PAN (p < ,001).WnioskiWyniki potwierdziły obecność NGW w grupach klinicznych. ZZA zakłóca mechanizm generowania wspomnień specyficznych w mniejszym stopniu niż zaburzenia nastroju. Ponadto osoby z grup klinicznych oceniają swoją przeszłość bardziej pesymistycznie niż z grup kontrolnych. Wzorzec wyników obejmuje zmniejszoną liczbę wspomnień pozytywnych u osób z epizodem depresji, a prawdopodobnie zwiększoną negatywnych – u osób z ALK.
Mental Health Centers. Preliminary evaluation of the pilot program implementation process
Authors: Biechowska Daria , Cechnicki Andrzej , Godyń Jan , Balicki Marek , Wciórka Jacek , Ciuńczyk Izabela , Galińska-Skok Beata 
Published: June 2022

Cel pracyCelem zaprezentowanych badań jest charakterystyka działających centrów zdrowia psychicznego oraz wstępna ocena procesu wdrażania modelu pilotażowego w obszarze opieki psychiatrycznej w Polsce.MetodaW badaniu wykorzystano polską wersję niemieckiej ankiety, która obejmuje cztery obszary: Podstawowe warunki projektu modelowego/pilotażu; Charakterystyka struktury organizacyjnej podmiotu leczniczego; Charakterystyka statystyczna świadczonych usług; Szczególne cechy systemu opieki psychiatrycznej w regionach modelowych/pilotażowych centrach zdrowia psychicznego.WynikiAnkietę wypełniło 19 z 27 centrów zdrowia psychicznego. Centra dysponują 428 miejscami w oddziałach dziennych i 1 971 łóżkami w oddziałach stacjonarnych. Większość centrów (15 z 19) współpracuje z podwykonawcami i wszystkie są finansowane ze środków publicznych. W odniesieniu do struktury organizacyjnej, to 8 centrów zostało założonych przez szpital psychiatryczny, a 11 centrów przy oddziałach psychiatrycznych szpitali wielospecjalistycznych. Usługi medyczne świadczone w centrach obejmują głównie psychiatrię i psychoterapię. W 2019 roku centra udzieliły usług medycznych łącznie 65 614 pacjentom. 8 432 pacjentów korzystało z co najmniej trzech form leczenia.WnioskiPierwszy pełen rok funkcjonowania CZP w pilotażu wskazuje na spodziewany kierunek zmian w opiece psychiatrycznej - osiągnięcie znacznego poziomu wdrożenia standardów opieki środowiskowej. W celu weryfikacji tego kierunku badania wymagają powtórzenia. Ograniczeniem przeprowadzonych badań był brak odpowiedzi na ankietę z 30% CZP. W przyszłości należy dążyć do co najmniej 90% wypełnionych ankiet.
Impact of Traceability Technology Adoption in Food Supply Chain Networks
Authors: Dong Lingxiu , Jiang Puping (Phil) , Xu Fasheng 
Published: June 2022

Improving traceability in food supply chains has been a big part of ongoing effort to reduce contamination risks and food waste. Recent technology advancement such as blockchain technology has propelled innovative retailers to promote food traceability system adoption in their supply chains. We develop a three-tier supply chain model with multiple upstream (tier 2) suppliers to investigate how traceability technology adoption affects incentives of supply chain members and whether and how its anticipated benefits can be realized. We find that full traceability brings direct revenue benefit to every supply chain member by saving uncontaminated food from disposal (pure traceability effect) but also leaves each tier of the supply chain vulnerable to its immediate downstream buyer’s exploitation through strategically lowering the purchasing price (strategic pricing effect). The interplay of the two effects may result in some of the supply chain members (even the retailer) being worse off with traceability adoption and the system being exposed to higher contamination risk; the latter is because of the weakened upstream supplier’s incentive to exert contamination risk-reduction effort. Moreover, we find that the supply chain network structure also influences the benefit distribution of traceability adoption: The retailer always benefits from traceability adoption in network structures where the tier 1 supplier’s strategic pricing power is eliminated or weakened; all supply chain members benefit from traceability adoption in a network with a large number of tier 2 suppliers. Finally, we show that alternative risk-mitigation schemes such as tier 2 coordination can diminish the value of traceability adoption, and partial traceability enabled by tier 1 product inspection can be more beneficial to the retailer than full traceability. This paper was accepted by Victor Martínez-de-Albéniz, operations management. Supplemental Material: The online appendices are available at https://doi.org/10.1287/mnsc.2022.4440 .
Single-shot ultrafast multiplexed coherent diffraction imaging
Authors: Xu Yingming , Pan Xingchen , Sun Mingying , Liu Wenfeng , Liu Cheng , Zhu Jianqiang 
Published: June 2022

Classic interferometry was commonly adopted to realize ultrafast phase imaging using pulsed lasers; however, the reference beam required makes the optical structure of the imaging system very complex, and high temporal resolution was reached by sacrificing spatial resolution. This study presents a type of single-shot ultrafast multiplexed coherent diffraction imaging technique to realize ultrafast phase imaging with both high spatial and temporal resolutions using a simple optical setup, and temporal resolution of nanosecond to femtosecond scale can be realized using lasers of different pulse durations. This technique applies a multiplexed algorithm to avoid the data division in space domain or frequency domain and greatly improves the spatial resolution. The advantages of this proposed technique on both the simple optical structure and high image quality were demonstrated by imaging the generation and evaluating the laser-induced damage and accompanying phenomenon of laser filament and shock wave at a spatial resolution better than 6.96 μm and a temporal resolution better than 10 ns.