bluuebunny/crossref_metadata_2025_split huggingface dataset:
Professional Master's Athletic Training Students' Career Influences Part II: Short-Term and Long-Term Career Intentions
Authors: Nokes Ryan D. , Pitney William A. , Nottingham Sara , Bowman Thomas G. 
Published: February 2022

Context
As athletic training education continues to evolve to a professional master's degree, understanding the career intentions of students preparing to graduate from professional master's programs is essential.

Objective
To examine the career intentions of second-year professional master's athletic training students and identify the factors that influence their intentions.

Design
Convergent mixed methods.

Setting
Online surveys and individual phone interviews.

Patients or Other Participants
A total of 80 second-year professional master's students (63 women, 13 men, 4 no response, age = 24.63 ± 2.29 years) who were enrolled in the final semester of their program in spring 2019 participated in the online survey. Ten survey respondents participated in follow-up phone interviews.

Data Collection and Analysis
An online survey was designed and administered to answer the research questions. Semistructured phone interviews were conducted as a follow-up to the survey to gain further insight into the research questions. The data from the survey and interviews were woven together and merged to provide a comprehensive display of results. Triangulation, member checks, memos, and peer debriefing were completed for trustworthiness.

Results
Two higher-order themes emerged from the data: career progression and factors influencing career intentions. We identified 3 lower-order themes for career progression: short-term career plans, concerns over lack of experience, and long-term career plans. Two lower-order themes were identified for factors influencing career intentions: clinical experience and mentorship.

Conclusions
Second-year professional master's athletic training students have short-term and long-term career plans. Their career intentions were influenced by past clinical experiences and the mentorship received from their clinical preceptors and faculty members during their professional education. Unfortunately, many students were having difficulty obtaining positions after graduation due to a lack of professional experience. As a result, some turned to internship or residency positions to gain experience.
Effectiveness of Multimodal Intervention to Improve Blood Culture Collection in the Emergency Department
Authors: Shaji Rosemary , Madigubba Haritha , Priyadarshi Ketan , Anandh P , Nathan Balamurugan , Vivekanandan M , Sastry Apurba Sankar 
Published: February 2022

Introduction:
The blood culture (BC) contamination was a significant problem in our hospital, especially in the emergency department (ED). The study, therefore, was undertaken to improve the BC collection in the ED.

Methods:
The study was conducted for 1 year divided into two phases of 6 months each: Preintervention phase and intervention phase (regular and phlebotomist groups). The interventions comprised implementing standard protocol for BC collection and conducting educational sessions. In preintervention and regular groups, the BCs were collected by interns and technicians, while dedicated phlebotomist did so in the phlebotomist group. Data were analyzed and interpreted for the contamination rate as well as compliance in adequate filling of the requisition form. Statistical Package for the Social Sciences (SPSS) version 22. A value of P < 0.005 was considered statistically significant, and P < 0.01 was considered statistically significant.

Results:
In the preintervention group, 13.7% of specimens were reported as contaminated which was reduced to 4.2% and 3.2% in the regular and phlebotomist group, respectively, after intervention. Compliance of health-care workers to various elements of BC collection protocol was also found to be significantly improved in the intervention phase compared to the preintervention phase (P < 0.001).

Conclusions:
Implementation of this multimodal intervention resulted in a drastic reduction in BC contamination and improvement in compliance to BC collection protocol and filling of various parameters in the BC requisition form, thus improving the overall effectiveness of BC testing. It was also noted that the contamination rate was further reduced by implementing dedicated phlebotomist.
Clinicopathological Spectrum and Response Pattern of Adolescent-onset Idiopathic Nephrotic Syndrome
Authors: Roy Ranjit Ranjan , Tonny Rummana Tazia , Akbar Romana , Sultana Nadira , Ali Asif , Ray Ashish Kumar , Sharmim Shanjida , Mamun Abdullah Al , Jesmin Tahmina , Huque Syed Saimul , Uddin Golam Muin , Begum Afroza 
Published: February 2022

Background:
There is a scarcity of published data regarding the clinical and pathological pattern of idiopathic nephrotic syndrome in adolescents in our country.

Materials and methods:
A retrospective analytical study was undertaken on 550 children with idiopathic nephrotic syndrome admitted to Bangabandhu Sheikh Mujib Medical University from January 2019 to July 2021. Data regarding clinical and laboratory parameters, current clinical status of the patients and their steroid responsiveness, complications, types of histopathological lesions, and treatment profile were retrieved from departmental automation. These parameters of the patients whose disease onset between 1 and <10 years of age (Group A) were compared to the same parameters of those with onset of disease between 10 and 18 years (Group B).

Results:
We found that hypertension, hematuria, and azotemia were more prevalent in childhood group than adolescent group. IFRNS was the most common disease course in Group B (56.2%) and more of them were currently on remission (80%). SRNS was more common in Group A (16.7%) and more of them were on relapse (76.16%) currently during the last follow-up. Precipitating factors such as infection and asthma were more in younger children. The rate of complication was more in childhood group in comparison to adolescent group. On renal biopsy specimen, minimal change disease (MCD) was the most common histological lesion in adolescent group (24.86%) compared to childhood group (16.16%). Adolescents (Group B) required less amount of second- and third-line immunosuppressive drugs than younger children (Group A).

Conclusions:
The overall clinical and histological condition was more favorable in adolescent group in comparison to childhood group in our setup. These findings necessitate larger prospective study in the future for further validation of this observation.
Andrographolide Protects Retinal Ganglion Cells in Rats with Glaucoma by Regulating the Bcl-2/Bax/caspase-3 Signaling Pathway
Authors: Li Jun , Lu Jing , Chen Guang , Li Dan 
Published: February 2022

Objective:
The aim is to investigate the protective effect of andrographolide (AP) on retinal ganglion cells (RGC) in rats with glaucoma and its mechanism.

Methods:
ninety-six adult male Wistar rats were randomly divided into normal control (NC) group, chronic ocular hypertension (CHOT) group, vehicle group, and AP group. The density of RGCs and the number of apoptotic cells in retinal slices were evaluated, and the function of RGC was evaluated by photopic negative wave response (PhNR). The expression of Bcl-2, Bax, and caspase-3 in the retina was detected.

Results:
(1) The density of RGC in the CHOT and vehicle groups were significantly lower than that in the NC and AP (P < 0.01). After AP intervention, the RGC density of the rats significantly increased (P < 0.01). The ganglion cell layer (GCL) of the CHOT and vehicle groups was obviously thinner, and the thickness of the GCL was partially restored in the AP group. (2) A large number of terminal deoxytransferase mediated dUTP nick end labeling (TUNEL) positive cells were found in the GCL of the CHOT and vehicle groups, but only a few TUNEL positive cells were found in the AP group. The percentage of TUNEL positive cells was 8.80 ± 4.97%, 37.00 ± 5.27%, 46.16 ± 6.50%, and 22.29 ± 3.52% for groups NC, CHOT, vehicle, and AP, respectively. (3) At 2 weeks, the amplitude of PhNR in the CHOT and vehicle groups decreased by 63.22 ± 13.89% and 57.88 ± 6.95%, respectively. The amplitude of PhNR in the AP group was only 22.56 ± 6.44% lower than that in the NC group. The AP intervention significantly reduced the decrease of the PhNR amplitude in CHOT eyes. (4) Compared with the NC group, the expression of anti-apoptotic protein Bcl-2 was decreased in the CHOT and vehicle groups, and the expression of the pro-apoptotic protein Bax and caspase-3 significantly increased in the CHOT and vehicle groups, which could be reversed by AP treatment. The trend of the reverse transcription-polymerase chain reaction was consistent with that of the western blot analysis.

Conclusion:
The protective effect of caspase-3/Bcl-2 may be achieved through the regulation of the Caspase-3/Bcl-2 pathway in the rat retina.
Cryopreserved Sporozoites with and without the Glycolipid Adjuvant 7DW8-5 Protect in Prime-and-Trap Malaria Vaccination
Authors: Watson Felicia N. , Shears Melanie J. , Matsubara Jokichi , Kalata Anya C. , Seilie Annette M. , Cruz Talavera Irene , Olsen Tayla M. , Tsuji Moriya , Chakravarty Sumana , Sim B. Kim Lee , Hoffman Stephen L. , Murphy Sean C. 
Published: February 2022

ABSTRACT.
Repeated intravenous (IV) administration of radiation-attenuated sporozoite (RAS) vaccines induces Plasmodium-specific CD8+ liver-resident memory T (Trm) cells in mice and achieves sterile protection against challenge. Our heterologous “prime-and-trap” vaccine strategy was previously shown to simplify and improve upon RAS vaccination. Prime-and-trap vaccination combines epidermal priming by DNA-encoded circumsporozoite protein (CSP) antigen followed by a single IV dose of freshly dissected RAS (fresh-RAS) to direct and trap activated and expanding CD8+ T cells in the liver. Prime-and-trap vaccination protects mice against wild-type sporozoite (spz) challenge. Assessment of prime-and-trap vaccines in nonhuman primate (NHP) models and/or humans would be greatly enabled if fresh-RAS could be replaced by cryopreserved RAS (cryo-RAS). Here, we investigated if fresh-RAS could be replaced with cryo-RAS for prime-and-trap vaccination in BALB/cj mice. Despite a reduction in spz vaccine liver burden following cryo-RAS administration compared with fresh-RAS, cryo-RAS induced a similar level of Plasmodium yoelii (Py) CSP-specific CD8+ liver Trm cells and completely protected mice against Py spz challenge 112 days after vaccination. Additionally, when the glycolipid adjuvant 7DW8-5 was co-administered with cryo-RAS, 7DW8-5 permitted the dose of cryo-RAS to be reduced four-fold while still achieving high rates of sterile protection. In summary, cryo-RAS with and without 7DW8-5 were compatible with prime-and-trap malaria vaccination in a mouse model, which may accelerate the pathway for this vaccine strategy to move to NHPs and humans.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEPUASAN KERJA DAN KINERJA KARYAWAN
Authors: Atmaja Sukarta 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui dan menjelaskan : pengaruh dari faktorfaktor kepuasan (kompensasi, lingkungan kerja dan karakteristik pekerjaan terhadap kepuasan kerja; pengaruh kepuasan kerja terhadap kinerja; pengaruh faktor-faktor kepuasan kerja (kompensasi, lingkungan kerja, karakteristik pekerjaan terhadap kinerja. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian explanatory research dengan pendekatan kuantitatif. variabel dalam penelitian ini adalah kompensasi, lingkungan kerja dan karakteristik pekerjaan sebagai variabel bebas, kepuasan kerja sebagai variabel mediator dan kinerja karyawan sebagai variabel terikat. Penelitian ini menggunakan data yang didapatkan dari kuesioner oleh responden . Metode analisis data yang digunakan adalah analisis deskriptif dan analisis jalur. Hasil analisis jalur menunjukkan bahwa kompensasi, lingkungan kerja dan karakteristik pekerjaan berpengaruh tidak signifikan terhadap kepuasan kerja; kepuasan kerja berpengaruh signifikan dan positif terhadap kinerja karyawan; kompensasi, lingkungan kerja dan karakteristik pekerjaan berpengaruh tidak signifikan terhadap kinerja karyawan.
Pengaruh Peran Orang Tua Terhadap Pemberian Vaksinasi Covid 19 di MAN I Kota Serang
Authors: Kurniatillah Nia , Hayat Fauzul , Nurjaman Nurjaman 
Published: February 2022

Penelitian ini dilatar belakangi oleh keinginan peneliti untuk mengetahui seberapa pengaruhnya peran orang tua siswa dalam pelaksanaan pemberian vaksinasi Covid-19 akan berdampak pada percepatan pelaksanaan kegiatan pembelajaran tatap muka di masa pandemi covid-19 dengan aman. Sehingga penelitian ini bertujuan untuk mengetahui pengaruh peran orang tua terhadap pemberian Vaksin Covid-19 pada siswa kelas XI MAN 1 Kota Serang. Penelitian dilaksanakan pada bulan Juni s/d Agustus 2021. Subjek dalam penelitian ini adalah siswa kelas XI MAN 1 Kota Serang, dengan keseluruhan sampel sebanyak 34 siswa. Metode penelitian yang digunakan adalah kuantitatif analitik. Analisis data menggunakan analisis regresi dengan bantuan program SPSS. Hasil penelitian yang diperoleh yaitu pengaruh signifikan antara Peran Orang Tua terhadap Pemberian Vaksin Covid-19 pada Siswa Kelas XI di MAN I Kota Serang. Hal ini dibuktikan dengan perolehan nilai sig = 0,015 < 0,05 dan F-hitung = 6,648. Dapat disimpulkan bahwa peran orang tua membawa dampak terhadap pemberian vaksin Covid-19.
Comprehensive Physiotherapy Program Improves the Medial Longitudinal Arch of a Male Adolescent with Bilateral Flexible Flat Foot: A Case Report
Authors: Thanaya Sayu Aryantari Putri , Jamaluddin Chika Nabella 
Published: February 2022

Introduction: Flat foot is a common foot deformity marked by the absence of the medial longitudinal arch of the foot. Flexible flat foot is usually symptomless but can affect the biomechanics of the lower extremity and lumbar spine, possibly increasing the risk of pain and injury. Conservative management, including physiotherapy, is important in flat foot management, yet the number of reports regarding physiotherapy for flat foot is scarce. Therefore, this case report aimed to describe a case of bilateral flexible flat foot in a male adolescent who was treated with a comprehensive physiotherapy program.
Case Description: A 17-year-old male presented to the physiotherapy clinic with flat foot deformity on both feet. The patient received an hour of comprehensive physiotherapy program per session, twice per week, which included lower extremity stretching, various foot and leg strengthening exercises, proprioception exercises, and an educational aspect. The footprint test was conducted and the patient was evaluated using the Arch Index. The Arch Index measurements according to Cavanagh and Rodgers decreased from 0.38 to 0.32 (left foot) and 0.35 to 0.28 (right foot). Likewise, Staheli’s Arch Index measurements also decreased from 1.54 to 1.02 (left foot) and 1.5 to 0.7 (right foot).
Conclusion: Following 20 physiotherapy sessions, the patient’s Arch Index measurements demonstrated an overall reduction, indicating noteworthy improvements in the medial longitudinal arch height. Hence, it can be concluded that a comprehensive physiotherapy program can help improve the medial longitudinal arch height, and thereby foot posture, of an adolescent with bilateral flexible flat foot.
Temporally resolved coastal hypoxia forecasting and uncertainty assessment via Bayesian mechanistic modeling
Authors: Katin Alexey , Del Giudice Dario , Obenour Daniel R. 
Published: February 2022

Abstract. Low bottom water dissolved oxygen conditions (hypoxia) occur almost every summer in the northern Gulf of Mexico due to a combination of nutrient loadings and water column stratification. Several statistical and mechanistic models have been used to forecast the midsummer hypoxic area, based on spring nitrogen loading from major rivers. However, sub-seasonal forecasts are needed to fully characterize the dynamics of hypoxia over the summer season, which is important for informing fisheries and ecosystem management. Here, we present an approach to forecasting hypoxic conditions at a daily resolution through Bayesian mechanistic modeling that allows for rigorous uncertainty quantification. Within this framework, we develop and test different representations and projections of hydrometeorological model inputs. We find that May precipitation over the Mississippi River basin is a key predictor of summer discharge and loading that substantially improves forecast performance. Accounting for spring wind conditions also improves
forecast performance, though to a lesser extent. The proposed approach generates forecasts for two different sections of the Louisiana–Texas shelf (east and west), and it explains about 50 % of the variability in the total hypoxic area when tested against historical observations (1985–2016). Results also show how forecast uncertainties build over the summer season, with longer lead times from the nominal forecast release date of 1 June, due to increasing stochasticity in riverine and meteorological inputs. Consequently, the portion of overall forecast variance associated with uncertainties in data inputs increases from 26 % to 41 % from June–July to August–September, respectively. Overall, the study demonstrates a unique approach to assessing and reducing uncertainties in temporally resolved hypoxia forecasting.
PREVENTION OF THE RISK OF POSTOPERATIVE VENTRAL HERNIAS WITH OPEN SURGICAL INTERVENTIONS ON THE ANTERIOR ABDOMINAL WALL
Authors: Мадьяров В.М. , Турсунов Р.Б. , Мухаметова С.П. , Кусманов М.Е. 
Published: February 2022

Предупреждение риска развития послеоперационных наружных грыж (ПНГ) живота является одной из актуальных проблем современной хирургии. ПНГ является серьезным поздним осложнением, которое встречается у 5-14 % прооперированных пациентов. Целью исследования было сформулировать наиболее важные меры для предотвращения возникновения вентральных грыж после лапаротомных оперативных вмешательств, а также прогнозирование возникновения или рецидива путем определения коллагена. В результате разработана концептуальная модель для улучшения профилактики ПНГ и ее рецидивов.
Prevention of the risk of developing postoperative external hernias (PEH) of the abdomen is one of the urgent problems of modern surgery. PEH is a serious late complication that occurs in 5-14% of operated patients. The aim of the study was to formulate the most important measures to prevent the occurrence of ventral hernias after laparotomy surgery, as well as to predict the occurrence or recurrence by determining collagen. As a result, a conceptual model has been developed to improve the prevention of PEH and its relapses.
STRESS AND PATHOGENETIC MECHANISMS OF DEVELOPMENT OF HYPOXIC-ISCHEMIC BRAIN DAMAGE IN THE FETUS AND NEWBORN (LITERATURE REVIEW)
Authors: Бережанская С.Б. , Созаева Д.И. , Каушанская Е.Я. , Кравченко Л.В. , Пузикова О.З. 
Published: February 2022

Антенатальный период - короткий, но один из самых важных в жизни индивидума. Именно он является первым этапом существования человека, определяющим благополучие в последующем, которое зависит от экологической и социальной ситуации, состояния здоровья матери к моменту зачатия и на протяжении всей гестации. При их нарушениях развивающаяся ишемия плаценты сопровождается различными патогенетическими процессами, стимулирующими состояние хронического воспаления, активацию иммунных клеток, апоптоз трофобластов, присутствующих в децидуальной оболочке. Чрезмерная активация этих механизмов приводит к аномальной плацентации с нарушением инвазии, ремоделирования сосудов и микроциркуляции плаценты, что приводит к одному из самых сильных стрессов, лежащих в основе гипоксически-ишемического поражения головного мозга у плода и новорожденного.
The antenatal period is short, but one of the most important in the life of an individual. It is he who is the first stage of human existence, determining well-being in the future, which depends on the ecological and social situation, the state of health of the mother at the time of conception and throughout gestation. With their violations, the developing ischemia of the placenta is accompanied by various pathogenetic processes that stimulate the state of chronic inflammation, activation of immune cells, apoptosis of trophoblasts present in the decidua. Excessive activation of these mechanisms leads to abnormal placentation with impaired invasion, vascular remodeling and microcirculation of the placenta, which leads to one of the most severe stresses underlying hypoxic-ischemic brain damage in the fetus and newborn.
K PROBLEMU SEOSKE KUCE I EKONOMSKOG DVORIŠTA KAO PREBIVALIŠTA I RADNOG CENTRA
Authors: Dubić Slavoljub 
Published: February 2022

Seoska kuća i dvorište, kao mjesto gdje seoska porodica prebiva i obavlja privrednu djelatnost, problem su opće društvene i kulturne adekvatnosti. Pri tome se s gledišta nastambe postavlja u prvom redu problem higijene, a s gledišta privredne djelatnosti problem izgradnje kuće i dvorišta u skladu s potrebama uspješnog rada u poljoprivredi.
Kao što se seoska kuća ne ograničava samo na funkciju stana, nego vrši i ekonomske funkcije, jer služi kao spremište zaliha i mjesto pripremanja hrane za stoku, preradu raznih biljnih i životinjskih proizvoda, kao mlijeka i dr., tako seosko dvorište uopće nije ograničeno samo na ekonomske funkcije, jer se članovi porodice u tolikoj mjeri po njemu kreću, da je dvorište zajedno s kućom mjesto rada i prebivanja porodice. Seosko dvorište služi osim toga svojim zgradama kao prebivalište stoci.
U tom smislu su seoska kuća, i dvorište napose, problem adekvatnosti potrebama higijene ljudi i stoke i podesnosti za ekonomske svrhe.
COMPARISON OF ALLUVIAL SOILS OF DIFFERENT LAND USE IN THE AREA OF THE NATIONAL PARK "UNA" WITH SPECIAL EMPHASIS ON THE DISTRIBUTION OF CADMIUM, NICKEL AND ARSENIC
Authors: Muhamedagić Fatima , Veladžić Mirsad , Zgorelec Željka , Žužul Silva , Rinkovac Jasmina 
Published: February 2022

UDK 631.41:631.482(1-751.2 Una)(497.6)
The paper presented results of a comparison of alluvial soils of different land use at two sites within the National Park "Una". The sites were related to a natural meadow (BUK) and artificial meadow (KLISA). The main objective of the research, in addition to the physical and chemical parameters of soil quality, was to determine the distribution of the total content of cadmium (Cd), nickel (Ni) and arsenic (As). The total content of these elements were observed in composite samples at two depths of 0-10 cm and 0-20 cm and horizons profile. Their total content was measured by atomic AAS. The results were analyzed using Kruskal – Wallis test (p≤0.05) using coefficient χ2. The results showed a single legality of the distribution of Cd, Ni and As in samples of soil profile, while the average soil samples showed unique legality of the distribution of observed elements.