bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perpendicular Magnetization Switching Driven by Spin‐Orbit Torque for Artificial Synapses in Epitaxial Pt‐Based Multilayers
Authors: Zhang Qiqi , Zhao Yunchi , He Congli , Huo Yuping , Cui Baoshan , Zhu Zengtai , Zhang Guangyu , Yu Guoqiang , He Bin , Zhang Yi , Lyu Haochang , Guo Yaqin , Qi Jie , Shen Shipeng , Wei Hongxiang , Shen Baogen , Wang Shouguo 
Published: October 2022

AbstractPerpendicular magnetization switching driven by spin‐orbit torque (SOT) exhibits nonvolatility and adjustability, which has great potential applications in magnetic random‐access memory and neuromorphic computing. In this work, the SOT efficiency in the Pt (001)/NiFe (Py) and Pt (111)/Py bilayers is first investigated, where the single crystal Pt films and polycrystalline Py films are grown by molecular beam epitaxy and magnetron sputtering, respectively. The (001)‐oriented Pt sample shows a larger SOT efficiency than that of the (111)‐oriented one, which is mainly attributed to the facet‐dependent intrinsic spin Hall effect of the Pt layer related to the Berry curvature of the electrical band structure. Then, the epitaxial Pt (001)‐based perpendicularly magnetized multilayers are designed to study the perpendicular magnetization switching driven by SOT. A continuous and stable reversal is successfully achieved, providing a conceivable candidate for reliable and variable imitation of the artificial synapses. The magneto–optical Kerr effect imaging proves that the sustainable change of magnetization state originates from the multiple site domain nucleation and growth in the ferromagnetic layer. This work provides an efficient method to enhance the SOT efficiency, as well as employs the epitaxial thin films in artificial synaptic devices for neuromorphic computing.
The correlation between different ultrasound planes and computed tomography measures of abdominal aortic aneurysms
Authors: Hill Brigid G , Holloway Rossi , Lim Joyce , Clifford Kari , Lesche Sarah , Letts James , Krysa Jolanda 
Published: October 2022

AbstractIntroductionUltrasound measurements of the aorta are typically taken in the axial plane, with the transducer perpendicular to the aorta, and diameter measurements are obtained by placing the callipers from the anterior to the posterior wall and the transverse right to the left side of the aorta. While the ‘conventional’ anteroposterior walls in both sagittal and transverse plains may be suitable for aneurysms with less complicated geometry, there is controversy regarding the suitability of this approach for complicated, particularly tortuous aneurysms, as they may offer a more challenging situation. Previous work undertaken within our research group found that when training inexperienced users of ultrasound, they demonstrated more optimal calliper placement to the abdominal aorta when approached from a decubitus window to obtain a coronal image compared to the traditional ultrasound approach.PurposeTo observe the level of agreement in real‐world reporting between computed tomography (CT) and ultrasound measurements in three standard planes; transverse AP, sagittal AP and coronal (left to right) infra‐renal abdominal aortic aneurysm (AAA) diameter.MethodologyThis is a retrospective review of the Otago Vascular Diagnostics database for AAA, where ultrasound and CT diameter data, available within 90 days of each other, were compared. In addition to patient demographics, the infrarenal aorta ultrasound diameter measurements in transverse AP and sagittal AP, along with a coronal decubitus image of the aorta was collected. No transverse measurement was performed from the left to the right of the aorta.ResultsThree hundred twenty‐five participants (238 males, mean age 76.4 ± 7.5) were included. Mean ultrasound outer to the outer wall, transverse AP and sagittal AP diameters were 48.7 ± 10.5 mm and 48.9 ± 9.9 mm, respectively. The coronal diameter measurement of the aorta from left to right was 53.9 ± 12.8 mm in the left decubitus window. The mean ultrasound max was 54.3 ± 12.6 mm. The mean CT diameter measurement was 55.6 ± 12.7 mm. Correlation between the CT max and ultrasound max was r2 = 0.90, and CT with the coronal measurement r2 = 0.90, CT and AP transverse was r2=0.80, and CT with AP sagittal measurement was r2 = 0.77.ConclusionThe decubitus ultrasound window of the abdominal aorta, with measurement of the coronal plane, is highly correlated and in agreement with CT scanning. This window may offer an alternative approach to measuring the infrarenal abdominal aortic aneurysm and should be considered when performing surveillance of all infra‐renal AAA.
The role of mitochondrial genome abundance in Alzheimer's disease
Authors: Harerimana Nadia V. , Paliwali Devashi , Romero‐Molina Carmen , Bennett David A. , Pa Judy , Goate Alison , Swerdlow Russell H. , Andrews Shea J. 
Published: October 2022

AbstractMitochondrial dysfunction is an early and prominent feature of Alzheimer's disease (AD), with impaired energy metabolism preceding the onset of clinical symptoms. Here we propose an update to the mitochondrial dysfunction hypothesis of AD based on recent results examining the role of mitochondrial genome abundance in AD. In a large post mortem study, we show that lower brain mitochondrial genome abundance is associated with a greater odds of AD neuropathological change and worse cognitive performance. We hypothesize that lower mitochondrial genome abundance impairs mitochondrial function by reducing mitochondrial bioenergetics, thereby impacting neuronal and glial cell function. However, it remains to be determined if mitochondrial dysfunction causes, mediates, or is a by‐product of AD pathogenesis. Additional support for this hypothesis will be generated by linking peripheral blood mitochondrial genome abundance to AD and establishing clinical trials of compounds that upregulate total mitochondrial genome abundance or boost mitochondrial mass.
Ozone‐3,6‐dihydroxynaphtha‐2,7‐disulphonate chemiluminescence system is used for online ozone detection
Authors: Xiong Yalin , Wang Zhuqing , Tang Lianbo , Chen Qi , Feng Yangrun , Xie Zhijin , Fu Dayou 
Published: October 2022

AbstractThe chemiluminescence (CL) reaction between ozone and 3,6‐dihydroxynaphtha‐2,7‐disulphonate (DNDS) was found under alkaline conditions. Therefore, a novel CL system for ozone detection was established. The CL signal of the CL system is weak, and the CL signal is enhanced by adding nonionic surfactants. It was found that adding 16.4 g/l Triton X‐100 can enhance the CL signal. The CL reagent activated by ultraviolet (UV) light produced a CL signal was nearly 10 times stronger than the CL reagent not activated by UV light; the CL signal was enhanced by adding 8 g/l NaHCO3 to the CL reagent irradiated by UV light. Through the optimization of these test conditions, a high‐selectivity, high‐sensitivity online detection method for ozone CL was established. The linear range was 0.5–150 ppbv, and the limit of detection (LOD) was 0.092 ppbv (S/N = 3).
Fertility discussions and concerns in childhood cancer survivors, a systematic review for updated practice
Authors: El Alaoui‐Lasmaili Karima , Nguyen‐Thi Phi Linh , Demogeot Nadine , Lighezzolo‐Alnot Joëlle , Gross Marie José , Mansuy Ludovic , Chastagner Pascal , Koscinski Isabelle 
Published: October 2022

AbstractPurposeTo provide ways to improve the clinical practice of fertility preservation (FP) for children, adolescents, and young adults (AYA) with cancer.DesignA systematic research of online databases was undertaken in March 2020 following the PRISMA criteria, including Medline and Web of Science.ResultsFifty‐nine articles were included. Surveys, interviews, and focus groups were used to collect data from patients, parents, and health care providers (HCPs). Four themes worth exploring emerged: (a) what do patients and professionals think of and know about FP? (b) what makes the fertility discussion happen or not? (c) what, retrospectively, led to FP being pursued or not? and (d) how do patients and HCPs feel about fertility issues?ConclusionA minority of AYAs preserve their fertility (banking assay for 45% of boys and 23% of girls). Yet fertility concerns have a significant impact on the quality of life of young cancer survivors. Although recommendations and guidelines regarding FP are available internationally, there are no specific guidelines as to how to conduct fertility counseling for children and adolescents. Some barriers are not removable, such as a poor prognosis of an obvious severe disease, time constraints for starting treatment, and cultural and religious beliefs. In response to aspects hindering patients and families to be receptive to any discussion at the time of diagnosis, psychological support could reduce the level of emotional distress and help restore a degree of open‐mindedness to open a window for discussion. Moreover, as the lack of knowledge of professionals about fertility is frequently pointed out as a limiting factor for fertility discussion, reinforcing professional training regarding FP could be proposed to promote fertility discussion and eventually referral for FP.
Perspectives surrounding fertility preservation and posthumous reproduction for adolescent and young adults with terminal cancer: Survey of allied health professionals
Authors: Barrett Francesca , Sutter Megan E. , Campo‐Engelstein Lisa , Sampson Amani , Caplan Arthur , Lawrence Morgan , Vadaparampil Susan T. , Quinn Gwendolyn P. 
Published: October 2022

AbstractBackgroundWhile all reproductive‐aged individuals with cancer should be offered fertility preservation (FP) counseling, there is little guidance over offers to adolescent and young adults (AYA) with terminal diagnoses, especially when considering posthumous assisted reproduction (PAR). The Enriching Communication skills for Health professionals in Oncofertility (ECHO/ENRICH) trains Allied Health Professionals (AHPs) to improve communication with AYAs with cancer. Little is known about AHPs' role in assisting in FP and PAR decisions.MethodsThis is a cross‐sectional survey of ECHO/ENRICH trainees' attitudes and experience with FP and PAR in AYA with terminal cancer.ResultsThe response rate was 61% (365/601). While 69% felt comfortable discussing FP with terminal AYA after ECHO/ENRICH training, 85% desired further education. The majority (88%) agreed FP should be an option for AYA with cancer, though some agreed offering FP provided false hope (16%) or was a waste of resources (7%). Most shared that avoidance of FP discussions was common practice, especially in the medically fragile, late‐stage disease, or among minors. Many attributed lack of conversations to oncology team goals. Only 9% had prior experience with PAR. Many were conflicted about how PAR reproductive material should be gifted and who should be permitted to use PAR. Several raised moral concerns for PAR, or discomfort advising family. Many voiced desire for additional PAR‐specific education.ConclusionECHO/ENRICH trainees had varied levels of exposure to FP in terminal AYA and limited experiences with PAR. Many expressed uncertainties with PAR, which may be alleviated with further training and transparent institutional policies.
Open trial of a brief, web‐assisted behavioural intervention to reduce thwarted belongingness and suicidal ideation among adolescents: The Supporting Grieving Teens intervention
Authors: Hill Ryan M. , Oosterhoff Benjamin , King Cheryl A. , Kaplow Julie B. 
Published: October 2022

AbstractBackgroundBereavement during childhood is associated with elevated rates of suicide‐related behaviours among youth. However, no interventions explicitly address suicidal ideation among bereaved youth. The Supporting Grieving Teens (SGT) programme was created as a preventive intervention to reduce suicide risk among bereaved youth.MethodsThis preliminary open trial evaluated the feasibility, acceptability and preliminary outcomes of the SGT intervention among a sample of bereaved adolescents. Participants were 32 adolescents, 12–17 years of age (M = 14.44, SD = 1.56; 87.5% female, 31.3% Hispanic, 31.3% African American/Black and 25.0% non‐Hispanic White), seeking bereavement‐related services at a trauma and grief speciality outpatient clinic. Participants completed a two‐session web‐assisted intervention prior to enrolling in standard outpatient therapy.ResultsThere was a high rate of completion of the intervention, with 93.8% of those who provided assent completing both intervention sessions. Youth reported high levels of satisfaction with the intervention. Preliminary evaluation of outcomes demonstrated that the intervention was associated with small but significant reductions in thwarted belongingness and suicide ideation over the course of treatment and follow‐up. However, reliable change indices indicated reliable improvements for only a subset of participants.LimitationsThis study utilised an open trial design without a control group, and so causality cannot be inferred. Additional limitations include the small sample size and limited variability in suicidal ideation in the sample.ConclusionsThe intervention shows promise as a brief, web‐assisted psychosocial intervention for activating youths' existing social support networks. Further research is needed to more rigorously evaluate the intervention.
Antidepressant‐Like Effect and Phenolic Profile of Brazilian Native and Exotic Species from Psidium Genus
Authors: Cavichioli Natalia , Dalmagro Ana Paula , Sasse Otto Rodolfo , Junges Lucas Henrique , Rebelo Andrey Martinez , Reinke Cássia Katrin , Zeni Ana Lúcia Bertarello 
Published: October 2022

AbstractDepression is one of the disorders involving mental health that most affects the population worldwide. Considering the available pharmacological therapies for the treatment of depression are ineffective in most patients, the search for new alternatives is crucial. In line with this, we investigated the phenolic profile, antidepressant‐like, and antioxidant effects triggered by the administration of aqueous extracts from Psidium guajava L. (GUA), Psidium cattleianum Sw. (CAT), and Psidium guineense Sabine (GUI) leaves in mice. Our results show that quercetin is the major compound of GUA and GUI, and o‐coumaric acid in CAT extracts. The acute and subchronic administrations of the three plant extracts exerted an antidepressant‐like effect in mice exposed to the tail suspension test, without changes on locomotor performance evaluated by the open field test. Furthermore, the GUI and CAT decreased oxidative stress markers, mainly lipid peroxidation and nitrites in the hippocampus, prefrontal cortex, liver, and plasma. Notably, GUA and CAT increased non‐protein thiols in all tissues. Therefore, the Psidium extracts demonstrated an antidepressant‐like effect in mice, and the antioxidant capacity of the extracts seems to underlie the behavioral effect.
The Effect of Dried Ginger (Gan Jiang) on Stomach Energy Metabolism and the Related Mechanism in Rats Based on Metabonomics
Authors: Chen Limei , Wang Hui , Chen Zhao , Zhuo Wenhao , Xu Ruixiang , Zeng Xin , He Qirui , Guan Yongmei , Li Hui , Liu Hongning 
Published: October 2022

AbstractDried ginger is a commonly used stomachic. Dried ginger is often used as a gastric protector to treat stomach‐related diseases. However, the effect of dried ginger on energy metabolism in stomach tissue of rats under physiological condition has not been studied. In this study, different doses of water extract of dried ginger were given to rats for 4 weeks. The activity of Na+‐K+‐ATPase, Ca2+‐Mg2+‐ATPase, SDH (succinate dehydrogenase) enzyme, ATP content, mitochondrial metabolic rate and mitochondrial number in stomach tissue of rats were measured. Analysis of potential biomarkers related to the effect of dried ginger on energy metabolism in stomach tissue of rats by metabonomics, and their metabolic pathways were also analyzed. The results revealed that there was no significant difference in Na+‐K+‐ATPase in high‐dose group (GJH), medium‐dose group (GJM) and low‐dose group (GJL) compared to the Control group. The Ca2+‐Mg2+‐ATPase activity was significantly increased in stomach tissue of GJH group and GJM group, but there were no significant changes in stomach tissue of GJL group. The SDH activity and the ATP levels were significantly increased in stomach tissue of GJH group, GJM group and GJL group. The mitochondrial metabolic rate was significantly increased in GJL group, but there was no significant change in GJM group and was inhibited in GJH group. These effects might be mediated by arginine biosynthesis, glutathione metabolism, arachidonic acid metabolism, glycerophospholipid metabolism, arginine and proline metabolism, purine metabolism pathway.
Microencapsulation of Phenolic Extract from Sea Grape (Coccoloba uvifera L.) with Antimutagenic Activity
Authors: Calderón‐Santoyo Montserrat , González‐Cruz Elda Margarita , Iñiguez‐Moreno Maricarmen , Ramos‐Martínez Osvaldo , Burgos‐Hernández Armando , Ragazzo‐Sánchez Juan Arturo 
Published: October 2022

AbstractThis study aimed to microencapsulate the sea grape ethanolic extract by the spray drying process, characterizing the obtained powder, and evaluating its antimutagenicity activity. Microparticles showed a mean size of 6.28 μm and a spherical shape with a smooth surface. The powder had a low moisture content (4.02±0.92 %) and water activity (0.27±0.01), and high solubility (76±3.60 %). Moreover, hygroscopicity (14.75±2.63 g/100 g of powder) and bulk density (0.63±0.03 g/cm3) values suggested that this powder can be easily handled at a pilot or industrial scale. In addition, microencapsulation protected the extract against oxidation by ultraviolet light, improved its thermal stability, and its antimutagenicity activity was similar to fresh sea grape extract. In conclusion, the microencapsulation with maltodextrin by spray drying technique is an alternative to protect bioactive compounds from sea grapes against environmental conditions, maintaining their antimutagenic activity.
A case of left foot drop as initial symptom of granulomatosis with polyangiitis: Triggered by COVID‐19 disease?
Authors: Weynand Marjolaine , Raftakis Ioannis , Chérif Mohammad Yassine , Lecomte Sophie , Badot Valérie 
Published: October 2022

AbstractIn Granulomatosis with polyangiitis (GPA), involvement of the peripheral nervous system is frequent but its occurrence as an initial presentation is unusual. This case highlights the importance of this occurrence to permit an early diagnosis. Moreover, GPA started after a coronavirus disease 2019 infection and could have been induced by this.
Guillain–Barré syndrome following COVID‐19 vaccine: A case report
Authors: Fakhari Mohammad Sadegh , Poorsaadat Leila , Mahmoodiyeh Behnam 
Published: October 2022

AbstractCoronavirus disease is a viral infection affecting different organs with various morbidities and mortality. Vaccines are used to control the disease. COVID‐19 vaccines have brought many benefits but their adverse effects should not be ignored. Here, we report a case of Guillain–Barré Syndrome Following Sinopharm COVID‐19 Vaccine.
A case of Hashimoto's thyroiditis following Graves' disease
Authors: Oueslati Ibtissem , Salhi Salma , Yazidi Meriem , Chaker Fatma , Chihaoui Melika 
Published: October 2022

AbstractGraves' disease is characterized by the presence of circulating autoantibodies that stimulate the TSH receptor, inducing hyperthyroidism and goiter. Hashimoto's thyroiditis is an autoimmune disease leading to thyroid tissue destruction by cell and antibody‐mediated immune processes. The occurrence of Hashimoto's thyroiditis following Graves' disease has been rarely reported. Its pathogenesis is not clear. Herein, we report the case of a 40‐year‐old woman who was referred to our department for thyrotoxicosis. Laboratory tests revealed overt hyperthyroidism. Thyroid scintigraphy showed an enlarged gland with diffusely increased tracer uptake, confirming the diagnosis of Graves's disease. The patient was treated with propranolol and thiamazole. Two months later, she received radioactive iodine therapy. Three years and 9 months later, the patient presented with hypothyroidism and very high levels of thyroperoxidase antibodies consistent with the diagnosis of Hashimoto's thyroiditis. She was treated with levothyroxine. The shift from Graves' disease to Hashimoto's thyroiditis was reported in the literature. However, its pathogenesis has not been clearly elucidated.
Unlocking G‐Quadruplexes as Targets and Tools against COVID‐19
Authors: Qin Geng , Zhao Chuanqi , Yang Jie , Wang Zhao , Ren Jinsong , Qu Xiaogang 
Published: October 2022

Comprehensive SummaryThe applicability of G‐quadruplexes (G4s) as antiviral targets, therapeutic agents and diagnostic tools for coronavirus disease 2019 (COVID‐19) is currently being evaluated, which has drawn the extensive attention of the scientific community. During the COVID‐19 pandemic, research in this field is rapidly accumulating. In this review, we summarize the latest achievements and breakthroughs in the use of G4s as antiviral targets, therapeutic agents and diagnostic tools for COVID‐19, particularly using G4 ligands. Finally, strength and weakness regarding G4s in anti‐SARS‐CoV‐2 field are highlighted for prospective future projects.
A Framework for Assessing Peaola Land and Nutrient Use Efficiency in the Field
Authors: Madsen Isaac 
Published: October 2022

AbstractCanola and pea intercropping (peaola) promises a number of benefits that could improve the efficiency and resilience of dryland agricultural systems. Using the correct methods for assessing these intercropping systems is important for determining whether or not an intercropping method is suitable in a particular instance. This article describes methods to assess two of the most common resource use efficiencies: land and nutrients. Earn 1 CEU in Crop Management by reading the article and taking the quiz at https://web.sciencesocieties.org/Learning‐Center/Courses.
Optimal soybean maturity group selection is influenced by planting date in northern production systems
Authors: Siler Thomas B. , Singh Maninder P. 
Published: October 2022

AbstractChanging climate conditions have resulted in a shift towards longer growing seasons in Michigan and other northern U.S. states, providing soybean [Glycine Max (L.) Merr.] growers an opportunity to achieve early planting dates (PDs). However, increasingly variable spring precipitation may result in a wide range of PDs. Current soybean maturity group (MG) recommendations are based only on optimal PD and may not fully utilize the available growing season. To determine how MG selection should be adjusted based on PD, six varieties ranging from MG 1.0 to 3.5 were planted on four PDs (from late April to late June) during the 2018 and 2019 growing seasons at two locations in Michigan. Seed yield increased by an average of 286, 171, and 73.0 kg ha−1 for each 0.5‐MG increase when planting was conducted on day of year (DOY) 120, 140, and 160, respectively. When planting was delayed to DOY 180, there was a yield reduction of 51.4 kg ha−1 for each 0.5‐MG increase. The increase in yield from using a late MG in early planting was correlated with an increase in seeds m−2 which was mainly driven by a consistent increase in cumulative growing degree days during pod and seed set. Results from this study indicate that soybean growers can increase seed yield and profitability by adjusting MG selection based on PD such that the maximum available growing season is utilized. Specifically, using a late MG when planting early and an early MG in late‐season planting can maximize yield and profits.