bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frequent pattern mining algorithms in fog computing environments: A systematic review
Authors: Fadaei Tehrani Ahmad , Sharifi Mahdi , Rahmani Amir Masoud 
Published: July 2022

SummaryRecent advances in technology have resulted in generating or collecting massive volumes of data from rich data resources such as sensors and mobile devices in Internet of Things (IoT). Using data mining techniques can help overcome the mining problem in Fog computing environments which include millions of IoT devices. In addition, it can optimize response times, recourse consumption, and scalability in IoT applications. Frequent pattern mining, as one of the fundamental data mining tasks, is used for finding hidden patterns in such large datasets. The traditional data mining algorithms have many challenges such as scalability and resource consumption. This systematic review aimed to investigate the data mining algorithms, which focus on handling massive datasets, and present a technical taxonomy including the transaction‐centric, item‐centric, distributed, and parallel topics. The transaction‐centric and MapReduce‐based approaches were mostly utilized by 37% and 38%, respectively. Additionally, item‐centric, distributed, and parallel algorithms were employed 12% and 13%, respectively. The response time as a Quality of Service (QoS) factor had the highest percentage in the estimations of data mining algorithms (55%), followed by scalability (25%), and cost (20%). To the best of our knowledge, no study has focused on fog‐computing frequent pattern mining algorithms as one of the most important data mining tasks. This article aims to present a systematic review of the frequent pattern mining algorithms in fog computing and discuss the issues, challenges, and research perspectives for helping academia and industry leverage the power of data mining algorithms in fog computing.
Was the decline of saltmarsh tabanid populations after the 2010 oil spill associated with change in the larval food web?
Authors: Husseneder Claudia , Bhalerao Devika R. , Foil Lane D. 
Published: July 2022

AbstractHorse flies of the species Tabanus nigrovittatus and Tabanus acutus are native to coastal marshlands. Their larvae are apex invertebrate predators, and their development is dependent on the food web in the marsh sediment. Surveillance of T. nigrovittatus after the 2010 Deepwater Horizon Oil Spill in the Gulf of Mexico showed population crashes of adult flies in southeast Louisiana marshes near oil landfall, but not in southwest Louisiana where oil did not reach. Sediment collection in 2011 from Louisiana marshes showed a near‐complete absence of larvae in the southeast yet high numbers in the southwest. We hypothesized that oil contamination destroyed critical components of the larval food web and/or residual toxicity led to larval death. We used 18S rRNA gene metagenomics to identify components of the food web in larval guts and sediment from southeast and southwest Louisiana marshes. Sediment oil contamination, biochemistry, and toxicity could not explain the lack of larvae in the southeast, because oiling at our high‐tide mark sites was low at the time of the study and toxicity was independent of sediment biochemistry. Hexapods were the main food web components in tabanid larval guts. Abundance of stink bug, vinegar fly, and mosquito species in the sediment was positively associated with the presence of larvae. However, these taxa were enriched in southeastern (near oil) versus southwestern (unoiled reference) sediment, and thus, lack of major food web components due to oiling could not explain lack of larva in the east. We conclude that the immediate crash in adult populations in oiled regions was the main cause for the absence of larvae the following year. While most saltmarsh arthropod groups had rebounded within a year after the oil spill, recovery of saltmarsh horse flies was ongoing for 5 years.
Complete operational voltage assessment of Shandong pilot offshore wind project
Authors: Cai Deyu , Liu Xumin , Xu Dapeng 
Published: July 2022

AbstractThis article presents a thorough methodology for the voltage assessment of pilot offshore wind project in Shandong province, China. The results presented in this paper can be considered as the milestone of the offshore wind research in Shandong Province since there is still no grid codes for offshore wind power plant grid connection in the local electrical power grid. It mainly consists of three parts. In the first part, a detailed model of the offshore wind farm created in the DIgSILENT PowerFacotry simulation platform is presented, including wind turbines, power converters, transformers, submarine cables and relevant control schemes. In the second part, nonlinear time‐domain simulations were performed to analyze the wind farm's active power, reactive power, and voltage conditions under different wind scenarios. Based on the simulations results, a dynamic reactive power compensation system was proposed, and the consequence of the reactive power compensation was also demonstrated using nonlinear time‐domain simulations.
Desmodium adscendens (Sw.) DC.: A magnificent plant with biological and pharmacological properties
Authors: Manzione Maria Giulia , Herrera‐Bravo Jesús , Sharifi‐Rad Javad , Kregiel Dorota , Sevindik Mustafa , Sevindik Emre , Salamoglu Zeliha , Zam Wissam , Vitalini Sara , Hano Christophe , Kukula‐Koch Wirginia , Koch Wojciech , Pezzani Raffaele 
Published: July 2022

AbstractDesmodium adscendens (Sw.) DC. is a plant of the Fabaceae family especially rich in flavonoids but also in alkaloids, terpenoids, steroids, phenols, phenylpropanoids, glycosides, and volatiles. This herb has been traditionally used in numerous countries all over the world for its pharmacological and biological properties (i.e., it has been used for the treatment of diarrheas, fever, epilepsy, asthma, leishmaniasis, gastroduodenal ulcer, diabetes, hepatic diseases, etc.). Given the wide uses of D. adscendens, this review summarizes all recent data on D. adscendens evaluating its phytochemistry as well as its ethno‐traditional and pharmacological properties. In addition, an association between the phytocompounds of this plant and its potential mechanism of action in cell and animal models has been investigated, focusing with a special emphasis on human experiments.
Consumption of probiotic yogurt and vitamin D‐fortified yogurt increases fasting level of GLP‐1 in obese adults undergoing low‐calorie diet: A double‐blind randomized controlled trial
Authors: Hajipoor Shima , Hekmatdoost Azita , Pasdar Yahya , Mohammadi Reza , Alipour Meysam , Rezaie Mansour , Nachvak Seyed Mostafa , Balthazar Celso Fasura , Sobhiyeh Mohammad Reza , Mortazavian Amir Mohammad , Cruz Adriano G. 
Published: July 2022

AbstractEnergy restriction and manipulation of macronutrient composition of the diet are the main approaches that are used by people who aim to lose weight. When such strategies are employed, appetite and endocrine regulators of satiety, such as gut peptides, all are deeply affected. The gut microbiota–brain axis controls energy homeostasis in humans by affecting central satiety and gut peptides. The purpose of this study was to evaluate if the synergistic effect of probiotics and vitamin D in yogurt matrix can modulate this effect. In the double‐blind, randomized, placebo‐controlled trial, 140 obese adults were randomly allocated into four groups: 1) regular yogurt plus low‐calorie diet; 2) PY plus low‐calorie diet; 3) vitamin D‐fortified yogurt plus low‐calorie diet, and 4) probiotic and vitamin D co‐fortified yogurt plus low‐calorie diet. All groups were encouraged to increase their physical activity. Glucagon‐like peptide‐1 (GLP‐1), peptide Tyrosin‐Tysrosin (PYY), ghrelin, anthropometric variables, insulin, fasting blood sugar (FBS), insulin resistance/sensitivity, 1,25(OH)2 D3, dietary intake, and physical activity were measured before and after 10 weeks. The difference between groups for GLP‐1 after 10 weeks was significant after adjusting for baseline GLP‐1 and protein intake as confounders. PY showed the largest effect size (ES) on GLP‐1 (p = 14.2) and FBS (p = 14) compared with others. Pairwise comparison of yogurts effect sizes on GLP‐1 showed a significant difference in group 1 vs. group 2 (p = .001), group 1 vs. group 3 (p = .003), and group 1 vs. group 4 (p = .048). Vitamin D‐fortified yogurt had the largest effect size on the serum level of vitamin D and it showed a significant difference with RY (p = .018) and PY (p = .002). Consumption of vitamin D‐fortified yogurt and PY could be regarded as a promising approach during calorie restriction.
Effects of Allium roseum L. extracts on the proliferation and the differentiation of the acute myeloid leukemia cell line U937
Authors: Ben Arfa Abdelkarim , Boulaaba Mondher , Merhi Faten , Bauvois Brigitte , Ingrid Arnault , Auger Jacques , Neffati Mohamed , Najjaa Hanen 
Published: July 2022

AbstractEpidemiologic studies keep up the proposition that Allium vegetables can lower the risk of cancers. Acute myeloid leukemia (AML) cells exhibit high proliferative potency and have a reduced capacity of undergoing apoptosis and maturation. The beneficial effects of Allium seem related to the organosulfur products generated upon processing of these species. For this purpose, the aim of this study was to test Allium roseum fresh (FAE), crude (CAE) and dried (DAE) aqueous extracts for activity against the human acute leukemia cell line (U937). As assessed by flow cytometry, inhibited cell proliferation was in a dose‐dependent manner. Firstly, study showed that cell growth was inhibited with 20 mg/mL using FAE and CAE (60% and 73% respectively). Secondly, our experiments clearly indicate that all A. roseum extracts do not induce cell apoptosis. This was confirmed by the soft binding of Annexin V to phosphatidylserine. Finally, the high expression of macrophage's marker CD11 associated with adequate morphological changes proves clearly the differentiation aspect produced by A. roseum extract. Taken together, these data suggest that A. roseum could be a promising candidate for the alternative medicine in the field of cancer therapy.
Rheological characterization and fouling deposition behavior of coconut cream emulsion at heat processing temperature range
Authors: Maghazechi Avan , Mohammadi Nafchi Abdorreza , Tan Thuan‐Chew , Easa Azhar Mat 
Published: July 2022

AbstractFouling deposition in the coconut cream emulsion (CCE) is considered a severe technical issue in the industry. Since the fouling deposition results from the heating effect on the CCE bulk, the heat‐induced structural changes in the CCE bulk at different temperatures were rheologically investigated in the first part of this study. The second part applied different heat treatment conditions to investigate generated fouling deposition (GFD). Chemical composition, FTIR, and SEM imaging were used to explore GFDs thoroughly. The increase in viscosity and storage modulus (G′) reflect such heat‐induced changes over the experimental conditions. More structural changes were predicted at around ≥85°C, accompanied by a sharp increase in viscosity and (G′), which was associated with the gelation of CCE. The conformational transition, fat agglomeration in CCE bulk, generated fouling deposits (GFDs) were significant around 70°C. The chemical composition of the GFD has shown an increasing trend in the protein, carbohydrates, and ash, meanwhile fluctuation in the fat contents with increasing temperature. The FTIR peaks showed novel peaks around temperature ≥85°C, which implied new amide groups or new protein conformation. The SEM images provided the different microstructures of GFDs at high‐temperature levels. More likely the GFDs appeared at temperature ≥85°C are a gel deposit layer. These findings strongly suggest that emulsion gelation was the primary cause of coconut cream fouling.
Facial nerve palsy: Narrative review on the importance of the eye and its assessment
Authors: Hasmat Shaheen , Low Tsu‐Hui ( Hubert) , Dusseldorp Joseph R. , Mukherjee Payal , Clark Jonathan R. 
Published: July 2022

AbstractNew solutions are emerging that address specific facial regions in facial nerve palsy (FNP). However the most dreaded consequence of FNP is paralytic lagophthalmos threatening the eye. A way to prioritize these regions is thus required. A review of the literature is conduced to capture the current concepts in evaluating FNP. Overall, patients are assessed from three perspectives: from the clinician's perspective using validated clinician‐based grading instruments, from patient's perspective based on FNP‐specific patient‐reported outcome measures, and from the perspective of the layperson. The existing tools however provide limited information regarding the relative importance of different regions of the face. The eye appears to be an area of great concern for the patient where most surgical therapies are directed at. Addressing ocular problems in FNP carry a high priority but this is not clearly reflected by the standard systems.
Up‐regulated LRRN2 expression as a marker for graft quality in living donor liver transplantation
Authors: Tomiyama Takahiro , Yamamoto Takuya , Takahama Shokichi , Toshima Takeo , Itoh Shinji , Harada Noboru , Shimokawa Mototsugu , Okuzaki Daisuke , Mori Masaki , Yoshizumi Tomoharu 
Published: July 2022

Abstract
The quality and size of liver grafts are critical factors that influence living‐donor liver transplantation (LDLT) function and safety. However, the biomarkers used for predicting graft quality are lacking. In this study, we sought to identify unique graft quality markers, aside from donor age, by using the livers of non‐human primates. Hepatic gene microarray expression data from young and elderly cynomolgus macaques revealed a total of 271 genes with significantly increased expression in the elderly. These candidate genes were then narrowed down to six through bioinformatics analyses. The expression patterns of these candidate genes in human donor liver tissues were subsequently examined. Importantly, we found that grafts exhibiting up‐regulated expression of these six candidate genes were associated with an increased incidence of liver graft failure. Multivariable analysis further revealed that up‐regulated expression of LRRN2 (encoding leucine‐rich repeat protein, neuronal 2) in donor liver tissue served as an independent risk factor for graft failure (odds ratio 4.50, confidence interval 2.08–9.72). Stratification based on graft expression of LRRN2 and donor age was also significantly associated with 6‐month graft survival rates. Conclusion: Up‐regulated LRRN2 expression of liver graft is significantly correlated with graft failure in LDLT. In addition, combination of graft LRRN2 expression and donor age may represent a promising marker for predicting LDLT graft quality.
Cascaded networks for the embryo classification on microscopic images using the residual external‐attention
Authors: Guo Wei , Liu Shijie , Gong Zhaoxuan , Zhang Guodong , Jiang Xiran 
Published: July 2022

AbstractEmbryo assessment and selection are usually based on the visual morphological analysis by expert embryologists. Although the embryologist assessment has been routinely used in clinical practice, it is highly dependent on the embryologist's experience and is very time‐consuming. Therefore, objective and efficient methods for automated embryo evaluation are in high demand. We proposed a framework of cascaded networks to hierarchically extract and integrate the microscopic image features for embryo classification. The cascaded networks consisted of a coarse network and a refined network. The coarse network produced a classification activation mapping (CAM) with the highest classification probability, which indicated the most discriminative regions of embryo classification. The refined network extracted and integrated the image features again by using both the CAMs and the corresponding original images. In addition, the residual external‐attention block (ResEA) was used in the refined network to better capture long‐range dependencies. Our cascaded networks were trained on a dataset of 7728 microscopic images of day 3 embryos from 1800 couples and evaluated on an independent testing dataset of 734 microscopic images. The accuracy, sensitivity, specificity, precision, and F1‐score were employed to evaluate the performance of our cascaded networks. Compared with the coarse network and the refined network, respectively, the cascaded networks without the ResEA improved the classification results of embryos. The ResEA block helped the cascaded networks to further improve all five metrics for better embryo classification. Our proposed cascaded networks also achieved better classification results than a junior embryologist did. The cascaded networks hierarchically make full use of image features for more effective learning, and the ResEA further improves the performance of embryo classification.
Effects of digital processing on repeatability assessment of a multiple reaction monitoring liquid chromatography–tandem mass spectrometry system by ISO 11843‐7
Authors: Machida Koichi , Kotani Akira , Hayashi Yuzuru , Hakamata Hideki 
Published: July 2022

AbstractISO 11843 part 7 (ISO 11843‐7) can provide a standard deviation (SD) of area measurements of a target peak through the stochastic behaviors of instrumental noises. The purpose of this study is to demonstrate that ISO 11843‐7 can be applied to assess repeatability in an isocratic liquid chromatography–tandem mass spectrometry (LC–MS/MS) system without repetitive measurements. The relative standard deviation (RSD) of the peak area of ergosterol picolinyl ester, which was used as an example, on a multiple reaction monitoring (MRM) chromatogram was determined by ISO 11843‐7. The RSD by ISO 11843‐7 (N = 1) was within a 95% confidence band of the RSD by repetitive measurements (N = 6). Moreover, the effects of digital smoothing, such as moving average, were also examined on the repeatability assessment in LC–MS/MS by ISO 11843‐7. From the results of the comparisons of the RSDs obtained by ISO 11843‐7 and the repetitive measurements, it was shown that suitable RSDs of the peak area were obtained from the smoothed MRM chromatograms by the moving average for narrow data point windows (e.g., one‐sixth of the peak width). In conclusion, the utility of repeatability assessment based on ISO 11843‐7 has been expanded for the validation of an LC–MS/MS system.
Evaluation of response to different COVID‐19 vaccines in vaccinated healthcare workers in a single center in Iran
Authors: Pourakbari Babak , Mirbeyk Mona , Mahmoudi Shima , Hosseinpour Sadeghi Reihaneh H. , Rezaei Nima , Ghasemi Raheleh , Esfandiari Fatemeh , Mamishi Setareh 
Published: July 2022

AbstractDue to the recent coronavirus disease 2019 (COVID‐19) pandemic and emergent administration of various vaccines worldwide, comprehensive studies on the different aspects of vaccines are in demand. This study evaluated antibody response after the second dose of the COVID‐19 vaccine in the Children's Medical Center personnel. The blood samples of 174 healthcare workers were gathered at least 10 days after vaccination. The administered vaccines included Oxford/AstraZeneca, COVAXIN, Sinopharm, and Sputnik V. This study assessed all antibodies employing ELISA methods, including anti‐SARS‐CoV‐2 neutralizing antibody by DiaZist and Pishtazteb kits, anti‐SARS‐CoV‐2‐nucleocapsid by Pishtazteb kit, and anti‐SARS‐CoV‐2‐Spike by Razi kit. The cutoff for the tests' results was calculated according to the instructions of each kit. Totally, 174 individuals with an average age of 40 ± 9 years participated in this study, the proportion of men was 31%, and the frequency of past COVID‐19 infection was 66 (38%). Sixteen (9%) personnel received Oxford/AstraZeneca, 28 (16%) COVAXIN, 29 (17%) Sinopharm, and 101 (58%) Sputnik V. anti‐SARS‐CoV‐2‐nucleocapsid and anti‐SARS‐CoV‐2‐Spike were positive in 37 (21%), and 163 (94%) participants and their mean level were more in adenoviral‐vectored vaccines (p value < 0.0001). Neutralizing antibody was positive in 74% using Pishtazteb kit while 87% using DiaZist kit. All antibodies' levels were significantly higher in those with a past COVID‐19 infection (p value < 0.0001). In conclusion, Oxford/AstraZeneca and Sputnik V had a similar outcome of inducing high levels of anti‐SARS‐Cov‐2‐spike and neutralizing antibodies, which were more than Sinopharm and COVAXIN. The titers of Anti‐SARS‐CoV‐2‐nucleocapsid antibody were low in all of these four vaccines.
Numerical study of the magnetic skin effect: Efficient parameterization of 2D surface‐impedance solutions for linear ferromagnetic materials
Authors: Abou El Nasser El Yafi Dima , Péron Victor , Perrussel Ronan , Krähenbühl Laurent 
Published: July 2022

AbstractThis work presents an efficient method based on asymptotic models in order to solve numerically eddy current problems in a bi‐dimensional setting with a high contrast of linear relative magnetic permeability μr ≫ 1 between a conductor and a dielectric subdomain. We describe a magnetic skin effect by deriving a multiscale expansion for the magnetic potential in power series of a small parameter δ which represents the skin depth. We make explicit the first asymptotics up to the order three. Some numerical results based on the finite element method will be presented to illustrate the magnetic skin effect and to validate the performance of the proposed asymptotic models in the dielectric medium. We confirm that the proposed asymptotics provide reduced computational costs for a wide range of physical parameters introduced in our problem.
The untapped potential of early career researchers in academic publishing: Lessons learned from the Journal of Emerging Investigators model
Authors: Otero Claire E. , Osinski Victoria , Mattison Kari A. 
Published: July 2022

Key points
The lack of formal training in peer review can be detrimental to the publishing activities of early career researchers, including graduate students and postdoctoral fellows.
Lack of recognition of the work of early career researchers (ECRs) in review means that journals cannot easily identify them as potential reviewers in the future.
Participation as peer‐reviewers increases understanding in early career researchers of their own writing and review process.
ECRs can be highly motivated to volunteer for journal editorial work—Journal of Emerging Investigators encourages this by offering many different roles.
Publishers that utilize and train early career researchers as peer‐reviewers can prevent poor reviewer practices.
Use of preprint peer review to educate and enculturate science undergraduates
Authors: McDowell Gary S. , Fankhauser Sarah , Saderi Daniela , Balgopal Meena , Lijek Rebeccah S. 
Published: July 2022

Key pointsUndergraduate science education should include education in scholarly practices like peer review.Authentic experiences in peer review increase science literacy and science identity.Peer review of preprints provides a means for undergraduates to be involved in peer review that is independent of journal gatekeeping processes.
For early‐career researchers by early‐career researchers: The GPNG model for advancing, promoting and supporting innovative research
Authors: Stiles Gregory , Pescinski Janina , Petrich Katharine , Ufimtseva Anastasia 
Published: July 2022

Key points
An early‐career researchers (ECR) journal can provide the vital mentorship and guidance needed for ECRs to overcome the unfamiliarity with a publishing process that inhibits the successful submission, revision and publication of ECR work.
ECR journals can address some of the exclusionary effects in academic publishing that are particularly pronounced for women, minorities and ECRs located outside the Global North.
A successful ECR publishing model has to extend into education, mentorship and post‐publication promotion to build confidence and encourage long‐term publication success.
The use of social media and outreach activities are vital to engage global ECR audiences as well as policymakers.