bluuebunny/crossref_metadata_2025_split huggingface dataset:
Familial Case of Darier Disease (Case Report)
Authors: Горланов И.А. , Леина Л.М. , Милявская И.Р. , Заславский Д.В. , Дроздова Л.Н. , Минеева О.К. 
Published: March 2022

Болезнь Дарье (фолликулярный дискератоз) – относительно редкое аутосомно-доминантное наследственное заболевание кожи, при котором имеется дефект в десмосомальных контактах, связанный с мутацией в гене ATP2A2. Заболевание обычно начинается во втором десятилетии жизни. Поражение кожи характеризуется множественными гиперкератотическими папулами желтовато-коричневого цвета преимущественно в себорейных зонах – на волосистой части головы, шее и туловище. Часто отмечается типичное поражение ногтевых пластинок. У части пациентов отмечается умственная отсталость и депрессия. Гистопатологически в очагах поражения обнаруживаются надбазальные щели в эпидермисе с акантолитическими и дискератотическими клетками. Нередко отмечаются трудности в постановке диагноза заболевания. В представленном клиническом наблюдении мальчик 14 лет длительное время наблюдался с диагнозом «себорейный дерматит», а его мать – с диагнозом «атопический дерматит». Диагноз заболевания ставится на основании анамнеза (наличие подобного заболевания у родителей), типичной клинической картины и гистологического исследования.
Darier’s disease is a relatively rare autosomal dominant genodermatosis with a defect in the desmosomal attachment due to a mutation in the ATP2A2 gene. The disease is characterized by skin lesions, such as multiple yellow-brownish hyperkeratotic papules predominantly in seborrheic areas on the head, neck, and trunk. Besides, typical nail damage is often found along with it. Some patients demonstrate mental retardation and depression. Histopathologically, the lesions reveal suprabasal clefts in the epidermis with acantholytic and dyskeratotic cells. Often, diagnosing this disease is noted to be difficult. In the presented clinical case, a 14-year-old boy was observed for a long time with a diagnosis of seborrheic dermatitis, and his mother with a diagnosis of atopic dermatitis. The diagnosis of Darier’s disease in the case was based on the anamnesis (the presence of a similar disease in the parents), typical clinical picture and the results of histological study.
Features of Large Macular Tears in Patients of the Republic of Uzbekistan
Authors: Акшей Кхера 
Published: March 2022

Цель исследования. Изучить этиологические и морфологические особенности больших разрывов макулы у пациентов в Республике Узбекистан.Материалы и методы. В настоящее исследование были включены 200 глаз (188 пациентов), у которых при первичном обследовании диагностирован большой разрыв макулы (критерием включения в исследование был минимальный диаметр разрыва 400 мкм). По классификации Gass на 96 глазах (48%) была диагностирована 3-я стадия, на остальных 104 глазах (52%) – 4-я стадия разрыва макулы. Средний возраст пациентов составил 52,88±0,83 года. Всем пациентам проводилось полное офтальмологическое обследование, включающее оптическую когерентную томографию (ОКТ). ОКТ использовалась для верификации диагноза и измерения диаметра разрыва макулы.Заключение. Большие разрывы макулы в 55,5% случаев обусловлены витреомакулярным тракционным синдромом, в 24,5% случаев – миопией и в 20% случаев – травмой глаза. Пациенты с разрывами макулы различной этиологии не различаются по остроте зрения, внутриглазному давлению, диаметру и стадии разрыва, длительности заболевания. Пациенты с разрывами вследствие витреомакулярной тракции были достоверно старше пациентов с разрывами вследствие миопии и травмы глаза. В 51,5% случаев разрыв макулы сочетается с катарактой.
The purpose of the study was to investigate the etiological and morphological features of large macular tears in patients in the Republic of Uzbekistan.Material and Methods. The study enrolled 200 eyes (188 patients), in which a large macular rupture was diagnosed at the initial examination (minimal diameter of the rupture was 400 μm). According to Gass classification, 96 eyes (48%) were diagnosed with stage 3, the remaining 104 eyes (52%) with stage 4 macular rupture. The mean age of the patients was 52.88±0.83 years. All patients underwent complete ophthalmological examination including optical coherence tomography (OCT). OCT was used to verify the diagnosis and to measure the macular rupture diameter.Conclusion. Large macular ruptures in 55.5% of cases were caused by vitreomacular traction syndrome, in 24.5% of cases by myopia and in 20% of cases by eye trauma. Macular tears of different etiologies did not differ in terms of visual acuity, intraocular pressure, diameter, stage of tear, and duration of the disease. Patients with ruptures due to vitreomacular traction were significantly older than patients with ruptures due to myopia and eye trauma. A macular rupture was associated with cataract in 51.5% of cases.
[Reseña del libro] La gobernanza de los sistemas educativos. Fundamentos y orientaciones
Authors: Del Castillo Pilar 
Published: March 2022

Francisco López Rupérez (2021). La gobernanza de los sistemas educativos. Fundamentos y orientaciones. 215 páginas. Narcea Ediciones-UCJC Stamp. Madrid. ISBN papel 978-84-277-2835-6/978-84-95891-91-4
Se trata de una reflexión pegada a la realidad, que no ignora los dos principales efectos que el COVID ha tenido sobre la educación: por un lado, ha acelerado los procesos de cambio de las políticas educativas, para adaptarlas a los desafíos del XXI (la globalización y la revolución digital). Por otro, se ha producido lo que el autor denomina “la centrifugación”, esto es, la aparición de nuevas brechas entre estudiantes que amenazan la cohesión social y la igualdad real de oportunidades...
DETECTION OF QUANTITATIVE LOCI CORRELATION WITH GROWTH TRAITES IN LOCAL QUAIL USING PCR- RFLP TECHNIQUE
Authors: S. A. Lajan , AL-Barzinji Y.M.S. 
Published: March 2022

The objective of this study was to investigate the polymorphisms of three loci (SEMA3E, GH and TLX) that related with growth traits in local quail. A total of 720 birds (males and females) from three lines (desert, brown and white) were used. The results revealed that the effects of the line were significant on bird body weight and carcass weight and dressing percentage at 180 days at age. The Best Linear Unbiased Prediction (BLUP) value overall birds for body weight was ranged from -9.2173 to 10.0117, these results showed there were significant differences among high and low BLUP value groups in three quail lines under study. The PCR-RFLP results overall three lines showed that there were three, three and two alleles for SEMA3E, TLX and GH locus, respectively. This alleles gives twelve differences genotypes, the desert male quail with ACABAA genotype and desert female quail with AAABAA genotype (high group) for three loci under study give significantly higher body and carcass weight compared with another groups. In conclusion results showed that there are agreements between BLUP values with PCR-RFLP results to select best birds and the selection process with molecular technique can play a major positive and rapid role to improve and increase growth traits in these lines of local quail in Iraqi Kurdistan region.
inteligencia estratégica aplicada al cambio
Authors: De Miguel Jesús 
Published: March 2022

Este ensayo trata sobre la manera en que la inteligencia puede aplicarse a los procesos de cambio que precisan abordar las organizaciones, particularmente las empresas en su mecanismo de adaptación a los entornos complejos e inciertos que caracterizan esta tercera década del siglo xxi. Para ello, el autor analiza brevemente el significado del cambio y como éste influye en la propia cultura de las organizaciones para, posteriormente, exponer cómo es fundamental que la inteligencia se aplique en tres campos principales: el de la seguridad, para con ella detectar, identificar, analizar y valorar los principales riesgos y amenazas a los que pueden enfrentarse las empresas; en el ámbito competitivo, explicando cómo se debe analizar el entorno inmediato (colaboradores, competidores, asociados, clientes, etc.) y el general (político, económico, social, ambiental, etc.). Por el amplio contexto en el que se aplica la inteligencia, se debe considerar desde un enfoque integral, lo que lleva a la tercera consideración del autor que es la necesidad de las empresas consultoras para promover alianzas estratégicas en el marco del concepto de inteligencia colaborativa.
NURETTİN TOPÇU’NUN “İSYAN AHLÂKI” ESERİNE ÖZEL ATIFLA: ÖĞRETMEN VE ŞAHSİYET MİMARİSİ
Authors: BASAT Orhan 
Published: March 2022

Sokrates’in Delf Mâbedi’ndeki “Kendini bil”, Yunus Emre’nin “İlim kendin bilmektir”, Hacı Bayram Veli’nin “sen seni bil, sen seni”, Hegel’in “kendini tanı” ifadeleri ve insanın tarih boyunca yaptığı bilme yolculuğunda ‘olması gereken’ eylemlerin neliğinin ardına düşen zihinlerin benzeri arayışlarında, yaşamın düşünceye konu yapılarak ideal bir evren/insan isteği ile iradeleri mayalama kişiyi; ‘acaba’ sözcüğüne, “ya yanılıyorsam” kritiğine aşina özne elinde şaşma’ya, hayrete, kendi tecrübesini ötekinin yaşanmışlığı ile mukayese ederek fidelenecek yeni yetkin/olgun bir insan özlemine ulaştıracak soruyu imler: Kimim ben?
Bu çalışmamızda Nurettin Topçu özelinde değeri görelilik-mutlaklık açmaz tartışmalarından sıyırarak, kişi eylemini (burada eğitici-öğretmen) tüm arka planıyla birlikte ele almayı; değer taşıyan varlığın (eğitici) değere konu eylemlerinin kişi-kişi, kişi-toplum ve kişi-evrensel insan ilişkileri içerisinde -ki bu ilişki bağlamsal olarak etik bir ilişkidir artık- anlamaya/bilmeye dönük olan, sonra bu bilme merkezli oluşturulmuş normatifliğin işaret ettiği değerlilerin belirlenmesinin izlerini sürmeyi ve en nihayetinde doğru eylemin hangi etik ilişkiler ve normlar içerebileceğini ele almayı deneyeceğiz.
Flares, Rotation, and Planets of the AU Mic System from TESS Observations
Authors: Gilbert Emily A. , Barclay Thomas , Quintana Elisa V. , Walkowicz Lucianne M. , Vega Laura D. , Schlieder Joshua E. , Monsue Teresa , Cale Bryson L. , Collins Kevin I. , Gaidos Eric , El Mufti Mohammed , Reefe Michael A. , Plavchan Peter , Tanner Angelle , Wittenmyer Robert A. , Wittrock Justin M. , Jenkins Jon M. , Latham David W. , Ricker George R. , Rose Mark E. , Seager S. , Vanderspek Roland K. , Winn Joshua N. 
Published: March 2022

Abstract
AU Mic is a young (∼24 Myr), pre-main-sequence M dwarf star that was observed in the first month of science observations of the Transiting Exoplanet Survey Satellite (TESS) and reobserved 2 years later. This target has photometric variability from a variety of sources that is readily apparent in the TESS light curves; spots induce modulation in the light curve, flares are present throughout (manifesting as sharp rises with slow exponential decay phases), and transits of AU Mic b may be seen by eye as dips in the light curve. We present a combined analysis of both TESS Sector 1 and Sector 27 AU Mic light curves including the new 20 s cadence data from TESS Year 3. We compare flare rates between both observations and analyze the spot evolution, showing that the activity levels increase slightly from Sector 1 to Sector 27. Furthermore, the 20 s data collection allows us to detect more flares, smaller flares, and better resolve flare morphology in white light as compared to the 2 minute data collection mode. We also refine the parameters for AU Mic b by fitting three additional transits of AU Mic b from Sector 27 using a model that includes stellar activity. We show that the transits exhibit clear transit timing variations with an amplitude of ∼80 s. We also detect three transits of a 2.8 R
⊕ planet, AU Mic c, which has a period of 18.86 days.
The Evolution of AGN Activity in Brightest Cluster Galaxies
Authors: Somboonpanyakul T. , McDonald M. , Noble A. , Aguena M. , Allam S. , Amon A. , Andrade-Oliveira F. , Bacon D. , Bayliss M. B. , Bertin E. , Bhargava S. , Brooks D. , Buckley-Geer E. , Burke D. L. , Calzadilla M. , Canning R. , Carnero Rosell A. , Carrasco Kind M. , Carretero J. , Costanzi M. , da Costa L. N. , Pereira M. E. S. , De Vicente J. , Doel P. , Eisenhardt P. , Everett S. , Evrard A. E. , Ferrero I. , Flaugher B. , Floyd B. , García-Bellido J. , Gaztanaga E. , Gerdes D. W. , Gonzalez A. , Gruen D. , Gruendl R. A. , Gschwend J. , Gupta N. , Gutierrez G. , Hinton S. R. , Hollowood D. L. , Honscheid K. , Hoyle B. , James D. J. , Jeltema T. , Khullar G. , Kim K. J. , Klein M. , Kuehn K. , Lima M. , Maia M. A. G. , Marshall J. L. , Martini P. , Melchior P. , Menanteau F. , Miquel R. , Mohr J. J. , Morgan R. , Ogando R. L. C. , Palmese A. , Paz-Chinchón F. , Pieres A. , Plazas Malagón A. A. , Reil K. , Romer A. K. , Ruppin F. , Sanchez E. , Saro A. , Scarpine V. , Schubnell M. , Serrano S. , Sevilla-Noarbe I. , Singh P. , Smith M. , Soares-Santos M. , Strazzullo V. , Suchyta E. , Swanson M. E. C. , Tarle G. , To C. , Tucker D. L. , Wilkinson R. D. 
Published: March 2022

Abstract
We present the results of an analysis of Wide-field Infrared Survey Explorer (WISE) observations of the full 2500 deg2 South Pole Telescope (SPT)-Sunyaev–Zel’dovich cluster sample. We describe a process for identifying active galactic nuclei (AGN) in brightest cluster galaxies (BCGs) based on WISE mid-IR color and redshift. Applying this technique to the BCGs of the SPT-SZ sample, we calculate the AGN-hosting BCG fraction, which is defined as the fraction of BCGs hosting bright central AGNs over all possible BCGs. Assuming an evolving single-burst stellar population model, we find statistically significant evidence (>99.9%) for a mid-IR excess at high redshift compared to low redshift, suggesting that the fraction of AGN-hosting BCGs increases with redshift over the range of 0 < z < 1.3. The best-fit redshift trend of the AGN-hosting BCG fraction has the form (1 + z)4.1±1.0. These results are consistent with previous studies in galaxy clusters as well as as in field galaxies. One way to explain this result is that member galaxies at high redshift tend to have more cold gas. While BCGs in nearby galaxy clusters grow mostly by dry mergers with cluster members, leading to no increase in AGN activity, BCGs at high redshift could primarily merge with gas-rich satellites, providing fuel for feeding AGNs. If this observed increase in AGN activity is linked to gas-rich mergers rather than ICM cooling, we would expect to see an increase in scatter in the P
cav versus L
cool relation at z > 1. Last, this work confirms that the runaway cooling phase, as predicted by the classical cooling-flow model, in the Phoenix cluster is extremely rare and most BCGs have low (relative to Eddington) black hole accretion rates.
Can Stellar-mass Black Hole Growth Disrupt Disks of Active Galactic Nuclei? The Role of Mechanical Feedback
Authors: Tagawa Hiromichi , Kimura Shigeo S. , Haiman Zoltán , Perna Rosalba , Tanaka Hidekazu , Bartos Imre 
Published: March 2022

Abstract
Stellar-mass BHs (sBHs) are predicted to be embedded in active galactic nucleus (AGN) disks owing to gravitational drag and in situ star formation. However, we find that, due to a high gas density in an AGN disk environment, compact objects may rapidly grow to intermediate-mass BHs and deplete matter from the AGN disk unless accretion is suppressed by some feedback process(es). These consequences are inconsistent with AGN observations and the dynamics of the Galactic center. Here we consider mechanical feedback mechanisms for the reduction of gas accretion. Rapidly accreting sBHs launch winds and/or jets via the Blandford–Znajek mechanism, which produce high-pressure shocks and cocoons. Such a shock and cocoon can spread laterally in the plane of the disk, eject the outer regions of a circum-sBH disk (CsBD), and puncture a hole in the AGN disk with horizontal size comparable to the disk scale height. Since the depletion timescale of the bound CsBD is much shorter than the resupply timescale of gas to the sBH, the time-averaged accretion rate onto sBHs is reduced by this process by a factor of ∼10–100. This feedback mechanism can therefore help alleviate the sBH overgrowth and AGN disk depletion problems. On the other hand, we find that cocoons of jets can unbind a large fraction of the gas accreting in the disks of less massive supermassive BHs (SMBHs), which may help explain the dearth of high-Eddington-ratio AGNs with SMBH mass ≲ 105
M
⊙.
Constraining the Baryon Loading Factor of AGN Jets: Implication from the γ-Ray Emission of the Coma Cluster
Authors: Shi Xin-Yue , Zhang Yi , Liu Ruo-Yu , Wang Xiang-Yu 
Published: March 2022

Abstract
High-energy cosmic rays (CRs) can be accelerated in the relativistic jets of active galactic nuclei (AGNs) powered by supermassive black holes. The baryon loading efficiency onto relativistic CR baryons from the accreting black holes is poorly constrained by observations so far. In this paper, we suggest that the γ-ray emission of galaxy clusters can be used to study the baryon loading factor of AGN jets, since CRs injected by AGN jets are completely confined in the galaxy clusters and sufficiently interact with the intracluster medium via a hadronic process, producing diffuse γ-rays. We study the propagation of CRs in the galaxy clusters and calculate the radial distribution of the γ-rays in the galaxy cluster with different injection rates from AGNs. By comparison with the γ-ray flux and upper limits of the Coma cluster measured by Fermi-LAT and VERITAS, we find the upper limit of the average baryon loading factor (defined as the efficiency with which the gravitational energy is converted into relativistic particles) to be η

p,grav < 0.1. The upper limit is much lower than that required to account for diffuse neutrino flux in the conventional blazar models.
Galaxy-scale Test of General Relativity with Strong Gravitational Lensing
Authors: Liu Xiao-Hui , Li Zhen-Hua , Qi Jing-Zhao , Zhang Xin 
Published: March 2022

Abstract
Although general relativity (GR) has been precisely tested at the solar system scale, precise tests at a galactic or cosmological scale are still relatively insufficient. Here, in order to test GR at the galactic scale, we use the newly compiled galaxy-scale strong gravitational lensing (SGL) sample to constrain the parameter γ
PPN in the parameterized post-Newtonian (PPN) formalism. We employ the Pantheon sample of Type Ia supernova observations to calibrate the distances in the SGL systems using the Gaussian Process method, which avoids the logical problem caused by assuming a cosmological model within GR to determine the distances in the SGL sample. Furthermore, we consider three typical lens models in this work to investigate the influences of the lens-mass distributions on the fitting results. We find that the choice of lens models has a significant impact on the constraints on the PPN parameter γ
PPN. By using a minimum χ
2 comparison and the Bayesian information criterion as evaluation tools to make comparisons for the fitting results of the three lens models, we find that the most reliable lens model gives the result of

γ

PPN

=

1.065

−
0.074

+
0.064

, which is in good agreement with the prediction of γ
PPN = 1 by GR. As far as we know, our 6.4% constraint result is the best result so far among recent works using the SGL method.
Mass Accretion Rates of the HectoMAP Clusters of Galaxies
Authors: Pizzardo M. , Sohn J. , Geller M. J. , Diaferio A. , Rines K. 
Published: March 2022

Abstract
We estimate the mass accretion rate (MAR) of 321 clusters of galaxies in the HectoMAP Cluster Survey. The clusters span the redshift range 0.17–0.42 and the M
200 mass range ≈ (0.5–3.5) × 1014
M
⊙. The MAR estimate is based on the caustic technique along with a spherical infall model. Our analysis extends the measurement of MARs for 129 clusters at z < 0.3 from the Cluster Infall Regions in the Sloan Digital Sky Survey and the Hectospec Cluster Survey to redshift z ∼ 0.42. Averaging over redshift, low-mass clusters with masses near 0.7 × 1014
M
⊙ roughly accrete 3 × 104
M
⊙ yr−1; more massive clusters with masses near 2.8 × 1014
M
⊙ roughly accrete 1 × 105
M
⊙ yr−1. Low- and high-mass clusters increase their MAR by approximately 46% and 84%, respectively, as the redshift increases from z in the range 0.17–0.29 to z in the range 0.34–0.42. The MARs at fixed redshift increase with mass and MARs at fixed mass increase with redshift in agreement with the ΛCDM cosmological model for hierarchical structure formation. We consider the extension of MAR measurements to z ∼ 1.
Incarner l’autorité arbitrale dépend-il du genre ?
Authors: Simon Corentin , Thomas Julie 
Published: March 2022

Cet article s’intéresse aux expériences des jeunes juges-arbitres de handball, garçons et filles, durant leur parcours de formation entre l’âge de 13 et 20 ans. Il questionne la manière dont de jeunes femmes et hommes « incarnent » cette fonction, en étudiant les configurations de pratique au sein des différents espaces de la socialisation arbitrale. Formé·e·s autour d’un modèle d’autorité commun encourageant des types de féminités et de masculinités hybrides, ces jeunes juges-arbitres sont incité·e·s durant les matchs à adopter des comportements genrés plus traditionnels. Les diverses configurations sexuées des matchs de handball mettent en jeu des rapports de pouvoir qui évoluent avec l’avancée en âge des juges-arbitres.
La servitude volontaire aujourd’hui : fragilité de l’individu souverain
Authors: Larralde Philippe 
Published: March 2022

On connaît la question posée au xvi e siècle par É. de La Boétie : « Comment est-il possible que le plus grand nombre obéisse à un seul homme » (le tyran) ? Face à cela, en principe, il y a une solution simple : « Soyez résolus à ne servir plus et vous voilà libres ». Pourtant, inexplicablement, certains montrent « une opiniâtre volonté de servir » ; telle est la servitude volontaire. Mais en démocratie il n’y a plus de « tyran ». Il n’y a plus, en principe, de négation arbitraire de la liberté. Si bien que la seule négation de celle-ci ne peut venir que de soi-même : dans une démocratie idéale (où ne pèserait aucun arbitraire) il n’y aurait de servitude que volontaire. Le présent texte propose une réflexion sur cette spécificité de la servitude volontaire aujourd’hui. Une telle réflexion fait apparaître la fragilité de l’individu souverain.
Beauté et sexualité
Authors: Vinson Alain 
Published: March 2022

La beauté d’un corps qui nous attire ne saurait être atteinte par nos étreintes et nos caresses. Autrement dit, la fascination devant la beauté ne ressortit, en aucune façon, à une pulsion érotique. « Le beau – dit Simone Weil – est ce qu’on désire sans vouloir le manger. Nous désirons que cela soit. » C’est dire que pour jouir de la beauté, dont Platon considère que, par rapport à d’autres entités, elle est celle qui « se manifeste avec le plus d’éclat », il ne faut pas s’en approcher ni vouloir se l’approprier.