bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-Reliance, Determination and Home-Attachment in Lutfiya Al-Dulaymi’s Hayat’s Garden
Authors: Mahmoud Amel 
Published: July 2022

This present research deals with the novel Hadiqat Hayat, Hayat’s Garden, (2003) by the Iraqi female author Lutfiya Al-Dulaymi (1939 - ). The discussion focuses on the struggles the main character Hayat undergoes while confronting the debilitating circumstances of the wars and the anguish of waiting for the absent husband. While analyzing the character of the protagonist, Hayat, specific features are illustrated and highlighted such as; her self-reliance and independence, firm resolution to overcome difficulties, and her strong attachment to her house specifically her garden. The personality of the single mother, which is caught in the protagonist Hayat, breaks the stereotypical image of the helpless widow as it reveals a strong character capable of conquering the social restrains and the economic challenges with her inner vigor, determination and optimistic soul. On the symbolic level, Hayat gains another dimension of reference through her name, which means life. In this way, she becomes an embodiment of the country, Iraq, itself while confronting the calamities of wars symbolizing its survival and its continuity.
The Impact of COVID-19 on Informal Employment and the Measures Taken by the Chinese Government: The Analysis of Street Vending Economy in Nanjing
Authors: Xu Siqi , He Xin 
Published: July 2022

To revitalize Chinese economic activities under the influence of the pandemic, the Chinese government adjusts the policies and attitudes about street vending. Taking Nanjing as a typical example of a city of street vending, the paper expounds in-depth on the positive impact of street vending on the economy after the pandemic. Meantime, it also describes the new management policies of street vending made by the Nanjing government to develop with a good trend. In addition, the paper directly reflects Nanjing people’s views on street vending and the resulting behavior through professional data. Finally, through the analysis of the advantages of street vending, it proves that the support from street vending in the Chinese economy is non-negligible after the pandemic.
Brevi note in tema di marketplace lending alla luce del nuovo regolamento europeo in materia di crowdfunding
Authors: Cipriani Lucrezia 
Published: July 2022

Crowdfunding platforms have been particularly relevant in the ambit of innovations introduced with the development of Fintech, including those that base their activity on lending (the so called “lending-based crowdfunding” platforms).
The active platforms - whose number in Italy is still relatively small - carry out a market activity that facilitates the matching of interests between those who are in surplus (and wish to use money towards a return), and those who are in deficit (and wish to obtain funding).
This article aims to provide a look at lending crowdfunding, with a twofold purpose:
(i) understanding how the relevant platforms can be legally qualified, also with regard to their compatibility with the activities reserved by law to financial intermediaries;
ii) analyzing the possible scenarios related to the “European Crowdfunding Service Providers” EU Regulation (ECSP), considering that only in recent years the Commission has decided to go beyond a mere monitoring of the sector.
المصطلح بين التأصيل القرآني والأجنبة المعاصرة
Authors: اسعد عباس كاظم ا.م.د. 
Published: July 2022

يتعرض البحث لبعض المصطلحات في العصر الحديث وما يقابلها في القرآن الكريم، بمنهج وصفي تحليلي؛ إذ إنّه يعطي تعريف المعجمات اللغوية للجذر الثلاثي للفظة، ويبيّن التوظيف القرآني الدقيق لها، ومن ثمّ يعود ليوضح الاستعمال اللغوي الحديث لها، ومدى تطوره واختلافه عمّا جاء في القرآن الكريم.
وكان هدف البحث وصف حالة التطور، وبيان التغير أو الاختلاف الذي حلّ باستعمال الألفاظ، ومن أهداف البحث البعيدة الدعوة إلى الرجوع بالمصطلحات إلى أصالتها العربية، وإعادة تشكيلها بمعناها القرآني العربي، فالقرآن الكريم هو معقل اللغة العربية، ومعينها الصافي الأصيل، واللغة العربية لها القدرة على التعبير عن الأشياء بمصطلحات لها دلالات دقيقة.
Identifying type Os: Spelling out the future of red blood cell products in military medicine
Authors: Chew Leon H. , Dhillon Paul 
Published: July 2022

LAY SUMMARYLife threatening trauma and severe hemorrhage are treated using several medical principles called damage control resuscitation (DCR). Red blood cell transfusion is an essential tool in DCR and is used to address a lack of oxygen delivery to the tissues and consequent abnormalities in human physiology. There are numerous challenges to accessing stable red blood cell products in austere and remote environments. This article discusses recent innovations in red blood cell products that improve stability and function in such environments.
El uso de estrategias y técnicas propagandísticas evocadoras de miedo en las distopías audiovisuales. El caso de Gilead en El cuento de la criada
Authors: Rebollo-Bueno Sara 
Published: July 2022

Este estudio aborda el uso de estrategias y técnicas generadoras de miedo de la teoría de la propaganda en el audiovisual, enfocándose en el análisis de la serie distópica de El cuento de la criada. El miedo es utilizado en propaganda como una herramienta de control social y dominación política. Esta investigación plantea si este instrumento propagandístico se utiliza en los sistemas políticos representados en el audiovisual, pues estos son reflejos de los miedos actuales en un futuro catastrófico. Para esto, utiliza un análisis de contenido que se aplica a las tres primeras temporadas de la serie mencionada a través de las escenas en las que aparecen Fred Waterford, Serena Joy y Tía Lydia, como representantes de Gilead en la narrativa.
การพัฒนาผลิตภัณฑ์ครีมนวดผมที่มีส่วนผสมของสารสกัดเปลือกส้มโชกุน
Authors: สุกใส วิไลลักษณ์ , สัตย์ซื่อ สถาพร , อุประวรรณา ฉัตรดนัย 
Published: July 2022

วัตถุประสงค์: เพื่อพัฒนาผลิตภัณฑ์ครีมนวดผมที่มีส่วนผสมของสารสกัดเปลือกส้มโชกุน
วิธีการศึกษา: การศึกษาในรูปแบบการวิจัยและพัฒนา โดยวิเคราะห์สถานการณ์ดูแลเส้นผมด้วยผลิตภัณฑ์ที่มีส่วนผสมของสมุนไพรจากธรรมชาติในปัจจุบันด้วยการสนทนากลุ่ม จากนั้นพัฒนาผลิตภัณฑ์ จากการประเมินคุณสมบัติทางกายภาพ ทางเคมี ประเมินความคงตัว ประเมินความรู้สึกในการใช้ ประเมินสภาพเส้นผมก่อนและหลังใช้ผลิตภัณฑ์ และประเมินความพึงพอใจผลิตภัณฑ์
ผลการศึกษา: พบว่ากลุ่มตัวอย่างมีความต้องการใช้ผลิตภัณฑ์ครีมนวดผมจากธรรมชาติที่ช่วยบำรุงเส้นผมและฟื้นฟูเส้นผมที่แห้ง ให้นุ่มสลวย ไม่พันกัน โดยมีเนื้อครีมที่ไม่เหนียวเหนอะหนะ ล้างออกง่าย มีกลิ่นหอมของส้ม และต้องการบรรจุภัณฑ์ในรูปแบบหลอดบีบ ที่มีขนาดแตกต่างกันเพื่อความสะดวกในการใช้งาน จากการประเมินคุณสมบัติทางกายภาพและเคมี พบว่าลักษณะเนื้อครีมเนียนละเอียดดีมาก สีของครีมที่มองเห็นเป็นสีเหลืองอ่อน มีกลิ่นส้มอ่อน ๆ ไม่มีกลิ่นเหม็นหืน ครีมมีการไหลที่ดี ไม่มีการเจริญของจุลินทรีย์หรือเชื้อรา ไม่มีการเกิด creaming และ cracking มีค่า pH 5-6 ซึมซาบดี ไม่เหนอะหนะ จากนั้นประเมินสภาพเส้นผม พบว่าเส้นผมแข็งแรง ไม่แห้งเสีย (ร้อยละ 87.05) ผมเรียบลื่น และมีความยืดหยุ่น (ร้อยละ 92.25) ไม่มีสะดุดไปตลอดเส้นผมสะท้อนถึงเส้นผมที่มีสุขภาพดี (ร้อยละ 89.15) และเส้นผมยืดหยุ่นไปตามแรงดึง (ร้อยละ 90.04) และประเมินความพึงพอใจผลิตภัณฑ์พบว่า อยู่ในระดับมาก ( = 4.40)
สรุป: จากผลการศึกษาทำให้ได้ผลิตภัณฑ์ครีมนวดผมจากสารสกัดเปลือกส้มโชกุนที่ทำให้เส้นผมแข็งแรง เรียบลื่น มีความยืดหยุ่น สัมผัสแล้วผมนุ่มลื่น และการประเมินความพึงพอใจผลิตภัณฑ์ พบว่า อยู่ในระดับมาก ดังนั้นผลิตภัณฑ์ที่มีส่วนผสมของสารสกัดธรรมชาติจึงเป็นอีกหนึ่งทางเลือกสำหรับผู้บริโภค และเป็นการเพิ่มมูลค่าของวัสดุทางการเกษตรให้เกิดประโยชน์
Análisis variables de calidad, económico de las operadoras de taxi y el impacto del servicio informal, ciudad de Riobamba
Authors: Salas Salazar Miriam del Rocio , Herrera Chico María Fernanda , Luis LLamuca José 
Published: July 2022

Introducción: El sector del transporte terrestre, caso de nuestro estudio operadores de taxis en la ciudad últimamente han disminuido sus ingresos debido al incremento de la informalidad que brindar este tipo de transporte más económico sin parámetros de calidad y seguridad uno de los factores la economía del país Objetivo. Analizar las variables de calidad, económico de las operadoras de taxi y el impacto del servicio informal, ciudad de Riobamba Metodología. Se aplico un diseño cuasi experimental en la que se tomó la participación de la cooperativa de taxis Bolívar Chiriboga de la ciudad de Riobamba se procedió aplicar una entrevista a algunos de sus conductores también se aplicó una encuesta a 37 usuarios utilizando las correspondientes herramientas de investigación Resultados. Según la encuesta de los usuarios de determino que la preferencia de los usuarios está en la calidad de Servicio y precio, servicio a tiempo y buenas condiciones del vehículo. Conclusiones. Si analizamos calidad y precio según la encuesta la preferencia está en el precio por el aspecto económico del país y la capacidad de respuesta al solicitar carreras, las operadoras informales en la ciudad ofrecen servicios a costos bajos en relación con la formales, al existir usuarios que poco o nada consideran su seguridad, pero si el factor económico da como respuesta a la reducción de los ingresos de los formales que no tienen estrategia creadas para combatir este problema.
Educação em saúde no manejo da nutrição enteral em idosos: uma revisão de escopo
Authors: Feitosa Gina Araújo Martins , Nóbrega Fernanda de Medeiros , Silva Susanne Pinheiro Costa e , Oliveira Fabiana Maria Rodrigues Lopes de , Barbosa Keylla Talitha Fernandes 
Published: July 2022

Objetivo: Buscar na literatura as evidências científicas disponíveis sobre educação em saúde no manejo da nutrição enteral em idosos e o uso de sonda. Metodologia: trata-se de revisão de escopo que abrangeu 3 estudos, após serem aplicados os critérios de inclusão e exclusão. Estes encontravam-se disponibilizados nas bases de dados MEDLINE/PubMed; Cumulative Index to Nursing and Allied Health Literature (CINAHL) e Cochrane, tendo como descritores idosos, nutrição enteral e educação em saúde. Resultados: Dos 349 registros encontrados, 140 foram excluídos por critérios de exclusão, sendo selecionados 206 para leitura dos respectivos títulos e resumos. Foram excluídas 195 publicações por não se adequarem aos critérios de inclusão, sendo pré-selecionados 11 trabalhos para leitura completa que, após essa etapa, originou um resultado de 3 estudos. Conclusão: Diante dos achados, observa-se que a educação em saúde melhora o manejo da nutrição enteral, propiciando resultados positivos como restrição da colonização de microrganismos multirresistentes, diminuição da ocorrência de complicações do uso da sonda, atenuação das despesas médicas, prevenção de novas hospitalizações, redução no déficit calórico, duração da ventilação mecânica e tempo de permanência na UTI. Mais estudos são necessários para avaliar que estratégia educacionais são mais efetivas e, assim, contribuir para melhorar o atendimento e cuidado de idosos em uso de sonda para nutrição enteral.
Caracterização epidemiológica dos casos de sífilis gestacional no estado de Pernambuco, Brasil
Authors: Lima Filho Carlos Antonio de , Bernardino Amanda de Oliveira , Santos Maria Emanuele do Rego , Matias Paulo de Tarso Alves , Miranda Anna Karinne Salgado , Torreão Sabrina Barbosa Nascimento , Araujo Junior Raimundo Cirino , Marques Aldo Lucas Duarte , Santana Neto Sebastião Alves , Borba Gimena de Lemos 
Published: July 2022

Objetivo: é traçar o perfil epidemiológico dos casos de sífilis gestacional no estado de Pernambuco, no período de 2015 a 2020. Metodologia: Trata-se de um estudo epidemiológico, retrospectivo, descritivo, com abordagem quantitativa acerca da sífilis gestacional no estado de Pernambuco. A coleta de dados se deu de março a abril de 2022 através do acesso ao Sistema de Informações de Agravos de Notificação (SINAN), base de dados vinculado ao Departamento de Informática do Sistema Único de Saúde (DATASUS). Resultados: Foi observado uma notificação de 12.401 casos de sífilis gestacional no estado, com predominância de mulheres entre 20-39 anos (72,6%), de raça parda (66,9%), com o ensino fundamental incompleto (32,3%). Sendo os testes não treponêmicos mais utilizados, em comparação aos não treponêmicos, observando que apesar da sífilis primaria ser a predominante, não houve a notificação de boa parte dessa variável. Conclusão: Evidenciou-se que a sífilis gestacional é um problema de saúde pública no estado, e que vem ao longo do tempo aumentando, eventuais erros no momento da notificação se configura como um real problema para o seu combate.
Casos de dengue no Amazonas nos anos de 2018 a 2022
Authors: Paixão Flávia Alice Wanderley , Oliveira Marilza Assunção de 
Published: July 2022

Objetivo: Realizar uma investigação epidemiológica sobre os casos de dengue no Amazonas, no período de 2018 a 2022. Metodologia: Trata-se de um estudo retrospectivo, descritivo com abordagem quantitativa sobre casos prováveis e a taxa de incidência de dengue no Amazonas, no período de 2018 a 2022. A coleta de dados foi realizada a partir de dados fornecidos por meio de boletins epidemiológicos do Ministério da Saúde e Fundação de Vigilância em Saúde do Amazonas nos anos de 2018 a 2022, cujos casos foram notificados pelo Sistema de Informação e Agravos de Notificação (SINAN). Resultados: Foram notificados 26.449 casos prováveis de dengue no Amazonas, com taxa de incidência de 754,8 casos/100 mil habitantes. A maior incidência de casos ocorreu no ano de 2019, com 363,9 casos/100 mil habitantes. No ano de 2022 houve redução importante no número de casos, registrados 3.657 casos prováveis e taxa de incidência de 58,0 casos/100 mil hab., onde a faixa etária mais acometida por dengue foi de adultos jovens com idade entre 20 e 39 anos, de ambos os sexos. Os boletins epidemiológicos analisados apontaram os dois sorotipos circulantes no Amazonas, que são DENV 1 e DENV 2. Conclusão: O estudo mostrou-se de grande relevância, já que a dengue é uma doença endêmica na região, cuja incidência pode variar conforme a sazonalidade e a quantidade de chuvas. Faz-se necessário conhecer as variações dos casos de dengue, a fim de buscar políticas públicas de conscientização a respeito da eliminação dos focos do mosquito e tratamento dos doentes.
USULAN PERBAIKAN PEKERJAAN PEMBUATAN SOFA DENGAN PENDEKATAN WORK METHOD ANALYSIS
Authors: Amri Irman , Masniar Masniar , Palengka Nicolaus 
Published: July 2022

Meubel victory adalah salah satu usaha yang memproduksi berbagai jenis perabotan rumah tangga berbahan dasar kayu, khususnya kursi sofa. Kondisi nyata yang sekarang terjadi pada meubel victory adalah proses pengerjaan yang dilakukan oleh operator belum dilakukan dengan optimal dan meyebabkan waktu yang lama. Adapun faktor lain yang mempengaruhi waktu operasi yang lama juga disebabkan oleh banyak elemen pekerjaan yang seharusnyaÂ dapat bersamaan tetapi dilakukan secara terpisah, selain itu dalam bekerja kurang ketelitian pada waktu bekerja. Tujuan dalam penelitian ini adalah efisiensi system kerja dari segi postur kerja dan tata letak pada penempatan peralatan dan perakitan, sehingga dapat diperoleh target dalam produksi kursi sofa. Adapun teknik pengolahan data yang penulis gunakan dalam penelitian ini adalah mengamati kegiatan operator pada waktu bekerja, menentukan tindakan selanjutnya. Setelah penulis melakukan penelitian pada para pekerja di meubel Victory dan memperoleh data-data yang dibutuhkan maka penulis melakuan pembuatan gambar peta kerja dan analisis data dan didapatkan hasil bahwa sistem kerja atau cara kerja para tenaga kerja pada meubel victory kota sorong belum efisien sehingga membutuhkan perbaikan cara kerja. Dalam penelitian ini penulis menggunakan metode Work Method Analysis yaitu metode pengamatan cara kerja atau dalam pembuatan sofa. perbaikan kerjanya dengan perubahaan tata tempat perakitan dan penyimpanan produk jadi, agar tempat pengerjaan tidak sempit dalam berkerja karena telah mendapatkan ruang yang luas untuk merakit sebuah produk.
ANALISIS PRA PENDIRIAN USAHA CAKE FISH BALL DENGAN PENDEKATAN STUDY KELAYAKAN BISNIS
Authors: Tajuddin Tamrin , Amri Irman , Sahid Moch Wahyu Umar 
Published: July 2022

Penelitian ini bertujuan untuk mengetahui gambaran kelayakan bisnis pada Kuliner Cake Fish Ball yang ditinjau dari aspek internal, yakni aspek pemasaran, aspek teknis dan teknologi, aspek manajemen, aspek sumber daya manusia, dan aspek finansial. Metode yang digunakan adalah metode survei. Metode pengumpulan data dilakukan dengan cara wawancara, observasi, dan studi sampling. Teknik analisis data melalui pendekatan kualitatif dan kuantitatif, data kualitatif dibutuhkan untuk aspek non finansial, dan kuantitatif dibutuhkan untuk aspek finansial dan aspek pemasaran melalui bantuan komputer program Microsoft Excel. Berdasarkan penelitian dari aspek pemasaran sertas aspek teknis dan teknologi usaha Cake Fish Ball layak untuk dijalankan, sedangkan dari aspek manajemen dan aspek sumber daya manusia masih layak, di perlukan peningkatan system manejerial untuk kelangsungan usaha dalam waktu Panjang. Hasil analisis aspek finansial melalui metode penilaian investasi layak untuk dijalankan berdasarkan perhitungan PP (Payback Period) 3.96 bulan, elebih singkat dari maksimum payback periodnya yaitu 5 tahun. Nilai NPV (Net Present Value) = Rp 609,363,604 > Rp 162,220,420. Hasil nilai IRR (Internal Rate of Return) 45,44% > nilai bunga yang berlaku yakni 10%. Hasil analisis BEP (Break Even Point) volume produksi dan penjualan 15,127 pcs pertahun ataun dengan harga jual seharga sebesar RpÂ 18,979 per pcs. Dari hasil data penelitian dan data hitungan dapat di simpulkan bahwa usaha kue Cake Fish Ball dengan isian ikan tuna layak didirikan dikota Sorong terhadap analisis kelayakan bisnis mempunyai aspek penting yang telah di uji dan layak.
Management of Late Blight of Potato caused by Phytophthora infestans through Botanical Aqueous Extracts
Authors: Mehmood Basharat , Azad Aneela , Rahim Nasir , Arif Shameem , Khan Muhammad R. , Hussain Abid , Tariq-Khan Muhammad , Younis Muhammad T. , Bashir Asma , Ahmed Sohail , Khan Javed R. , Tariq Sahira , Jamil Muhammad 
Published: July 2022

Phytophthora infestans causing late blight is one of the most devastating tomato and potato disease that caused considerable yield losses globally including Pakistan. Due to repeated and injudicious synthetic fungicides applications for the control of late blight of potato, the fungicide resistance in P. infestans led to persistence and surveillance late blight of potato. The study was carried out to evaluate the efficacy of Garlic (Allium sativum), Neem (Azadirachta indica), Turmeric (Curcuma longa), Mint (Mentha) at 10%, 20% and 30% concentration as bio-fungicides against late blight of potato. In-vitro effect of plant extracts of A. sativum, A. indica, C. longa and Mentha were evaluated on percent inhibition and radial growth of pathogen. A. sativum and A. indica at 30% concentration was found more effective in minimizing the mycelial growth of P. infestans with inhibition of 58.4% and 43.9% respectively as compared to control. In the greenhouse trial, overall potato late blight disease incidence was minimum 5.81% where A. sativum extract was used followed by A. indica at 30% concentration resulted 8.45% incidence as compared to control 61.18%. Furthermore, the 30% aqueous extracts of A. sativum found highly effective against late blight disease with 15.4% severity, as compared to control with 54.13% disease coverage. Application of A. sativum and A. indica aqueous plant extracts with a concentration of 30% was found most promising and effective measure against late blight pathogen. Study provides environmentally benign mileage in organic vegetable production against hazardous synthetic agro-chemicals.
Changes of Peripheral Th17 Cells Subset in Overweight and Obese Children After Body Weight Reduction
Authors: Artemniak-Wojtowicz Dorota , Kucharska Anna M. , Stelmaszczyk-Emmel Anna , Majcher Anna , Pyrżak Beata 
Published: July 2022

BackgroundObesity has been a growing problem in young patients leading to serious metabolic complications. There are many studies supporting the idea, that obesity should be considered as a chronic inflammation closely associated with immune system alterations. Th17 subpopulation is strongly involved in this process. The aim of our study was to evaluate circulating Th17 cells in overweight and obese children and explore the relationships between Th17 subset and metabolic parameters.MethodsWe evaluated peripheral Th17 cells in fresh peripheral blood samples from 27 overweight and obese and 15 normal-weight children. Th17 cells were identified by flow cytometry using monoclonal antibody and intracellular IL-17A staining. Th17 cells were defined as CD3+CD4+CD196+IL-17Aic+. The analysis involved anthropometric and metabolic parameters measured at baseline and three months after the change of lifestyle and diet. We evaluated the relationship between metabolic parameters and Th17 cells.ResultsIn overweight and obese children we found significantly higher Th17 cells percentage compared to normal weight controls (median 0.097% (0.044 - 0.289) vs 0.041% (0.023 - 0.099), p = 0.048). The percentage of Th17 cells decreased statistically significantly in children who reduced weight after the intervention (0.210% (0.143 - 0.315) vs 0.039% (0.028 - 0.106), p = 0.004). In this group we also noticed statistically significant reduction of TC and LDL-C concentration (p = 0.01, p = 0.04, respectively).ConclusionsObesity in children is associated with increased percentage of peripheral Th17 cells. Weight reduction leads to significant decrease of circulating Th17 cells and improvement of lipid parameters. This significant reduction of proinflammatory Th17 cells is a promising finding suggesting that obesity-induced inflammation in children could be relatively easily reversible.
Acute Thermoregulatory and Cardiovascular Response to Submaximal Exercise in People With Multiple Sclerosis
Authors: Gervasoni Elisa , Bertoni Rita , Anastasi Denise , Solaro Claudio , Di Giovanni Rachele , Grange Erica , Gunga Hanns-Christian , Rovaris Marco , Cattaneo Davide , Maggioni Martina Anna , Merati Giampiero 
Published: July 2022

BackgroundHeat sensitivity occurs in a high percentage of people with multiple sclerosis (PwMS), in response to environmental or exercise-induced increase in body temperature. However, the kinetic and magnitude of adaptation of the internal load and of the core body temperature (CBT) to a submaximal continuous exercise has been poorly addressed in PwMS; this may be relevant for the brief exercise bouts usually occurring in normal daily life. The aim of this work was to evaluate whether multiple sclerosis influences the acute adaptation of the internal load, the CBT and the perceptual load in response to a constant submaximal work step.MethodsCBT has been continuously monitored (0.5 Hz) by a validated wearable heat-flux sensor and electrocardiography was recorded (250 Hz) by a wearable device during a standard 6-minute walk test (6MWT) in 14 PwMS (EDSS, 4.7 ± 1.2; disease duration: 13.0 ± 10.2 years; m ± SD) and 14 age, sex and BMI-matched healthy subjects (HS). The rate of perceived exertion (RPE) of the lower limbs was assessed during the 6MWT by the Borg scale (6-20).ResultsAs expected, PwMS walked a significantly shorter distance (361 ± 98 m) than the HS group (613 ± 62 m, p&lt;0.001 vs PwMS). However, the kinetics of adaptation of CBT and the magnitude of CBT change from baseline did not differ between groups. Similarly, heart rate (HR) kinetics and HR change from baseline were comparable between groups during the 6MWT. Finally, lower limbs RPE gradually increased during the exercise test, but without significant differences between groups.ConclusionThe internal load, the metabolic heat production, and the perceptive load due to a standard submaximal walking exercise seems to be preserved in PwMS, suggesting a comparable acute heat production and dissipation during exercise. Therefore, it is unlikely that the different distance achieved during the 6MWT may be caused by altered thermoregulatory responses to exercise. Rather, this appears to be a consequence of the known increased energy cost of locomotion in PwMS.