bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rate and Frequency of Poultry Manure on Growth and Yield of Fluted Pumpkin (Telfairia Occidentalis Hook. F.)
Authors: Akintoye Oluwatomilayo Hannah , Odedina Joy Nwakaego , Makinde Eyitayo Adekunle , Adigbo Sunday Ojo 
Published: August 2022

Abstract
Fluted pumpkin (Telfairia occidentalis Hook. F.) cultivation is predominantly done by smallholder farmers but scarcity and high cost of inorganic fertilizers have limited its usage and shifted to viable alternative. Field experiments were carried out in the Crop Research Farm, Federal University of Agriculture, Abeokuta, Ogun State Nigeria from November 2018 to August 2019 and from August 2019 to August 2020 cropping seasons to determine the effects of poultry manure (PM) rate and frequency of application on agronomic performance of fresh shoot, pod and seed yields of Telfairia occidentalis. The study involved three rates: 5, 10 and 15 t ha− 1 of PM as main plot and four frequency of PM application: once, twice, thrice and at every harvest and a control plot laid out in split-plot arrangement and fitted into a Randomized Complete Block Design, replicated three times. In 2018, Poultry manure at 15 t ha− 1 increased fresh shoot weight at 6 to 14 weeks after planting (WAP) relative to 5 t ha− 1 and 10 t ha− 1 PM rate. In 2019, interaction of PM at 5 t ha− 1 applied thrice significantly increased fresh shoot weight by 85.4% at 14 WAP relative to 15 t ha− 1 PM applied once. Interaction of PM at 10 and 15 t ha− 1 applied thrice and at every harvest respectively gave similar results on cumulative fresh shoot weight while the plants in control plots produced significantly lower fresh shoot weight in 2018. There were no significant differences observed in weight of pod and seed weight/plant with PM rate, frequency and interaction in 2018 and 2019 cropping. The study concluded that 10 t ha− 1 PM rate applied thrice enhanced cumulative fresh shoot yield in fluted pumpkin in the study area.
Transcriptome and Population Structure of Glassy-winged Sharpshooters (Homalodisca vitripennis) with Varying Insecticide Resistance in Southern California
Authors: Ettinger Cassandra , Byrne Frank , Pacheco Inaiara de Souza , Brown Dylan , Walling Linda , Atkinson Peter , Redak Richard , Stajich Jason 
Published: August 2022

Abstract

Background
Homalodisca vitripennis Germar, the glassy-winged sharpshooter, is an invasive insect in California and a critical threat to agriculture through its transmission of the plant pathogen, Xylella fastidiosa. Quarantine, broad-spectrum insecticides, and biological control have been used for population management of H. vitripennis since its invasion and subsequent proliferation throughout California. Recently wide-spread neonicotinoid resistance has been detected in populations of H. vitripennis in the southern portions of California’s Central Valley. In order to better understand potential mechanisms of H. vitripennis neonicotinoid resistance, we performed RNA sequencing on wild-caught insecticide-resistant and relatively susceptible sharpshooters to profile their transcriptome and population structure.
Results
We identified 81 differentially expressed genes with higher expression in resistant individuals. The significant largest differentially expressed candidate gene linked to resistance status was a cytochrome P450 gene with similarity to CYP6A9. Furthermore, we observed an over-enrichment of GO terms representing functions supportive of roles in resistance mechanisms (cytochrome P450s, M13 peptidases, and cuticle structural proteins). Finally, we saw no evidence of broad-scale population structure, perhaps due to H. vitripennis' relatively recent introduction to California or due to the relatively small geographic scale investigated here.
Conclusions
In this work, we characterized the transcriptome of insecticide-resistant and susceptible H. vitripennis and identified candidate genes that may be involved in resistance mechanisms for this species. Future work should seek to build on the transcriptome profiling performed here to confirm the role of the identified genes, particularly the cytochrome P450, in resistance in H. vitripennis. We hope this work helps aid future population management strategies for this and other species with growing insecticide resistance.
PERANCANGAN UI/UX SEMARANG VIRTUAL TOURISM DENGAN FIGMA
Authors: Al-Faruq Muhammad Naufal Muhadzib , Nur’aini Siti , Aufan Muhammad Haikal 
Published: August 2022

Kota Semarang merupakan salah satu kota besar yang ada di Indonesia dan memiliki banyak cagar budaya. Pemerintah Kota Semarang telah berupaya melakukan pemugaran beberapa cagar budaya agar lebih layak menjadi tujuan wisata. Hal tersebut dilakukan dalam upaya untuk meningkatkan ekonomi lokal. Usaha pemerintah Kota Semarang tidak berhenti sampai pada pemugaran cagar budaya, tetapi juga dengan melakukan berbagai promosi agar Kota Semarang dikenal lebih luas sebagai kota tujuan wisata. Untuk mendukung upaya pemerintah tersebut, penulis mempunyai gagasan berupa perancangan prototype Aplikasi Semarang Virtual Tourism. Pengumpulan data dilakukan dengan observasi dan wawancara. Sedangkan perancangan prototype menggunakan Figma. Figma dipilih sebagai media untuk merancang prototype ini karena Figma berbasis cloud sehingga memudahkan kerja sama tim. Aplikasi Semarang Virtual Tourism ini dirancang dengan desain yang sederhana dan menarik agar memudahkan pengguna. Aplikasi Semarang Virtual Tourism ini dapat memberikan informasi tentang cagar budaya dan kuliner yang ada di Kota Semarang. Kata Kunci: Semarang City, prototype, figma
Integrating into the System: Local Self-Government in the Context of the New Federal Reform
Authors: Zazulina Mariya 
Published: August 2022

The author analyzed the upcoming reform of local self-government initiated by amendments to the Constitution of the Russian Federation (2020) and the Draft Federal Law No. 40361-8 "On general principles of the organization of local self-government in a unified system of public authority", submitted to the State Duma of the Russian Federation in December 2021.
The research objective was to identify and analyze the features of the reorganization of local self-government during its integration into a unified system of public authority and the implementation of innovations proposed by the new law on local self-government. The analysis included the legislative foundation and various data on local self-government provided by the Ministries of Finance and Justice. The author concentrated on the unified system of public power, the local self-government as an element of this system, the proposed innovations, and their consequences for the institutional organization of local self-government. At the new stage, such problems of local self-government as poor manageability and low efficiency are likely to be solved by including them in the unified system of public authority. Governmentalization increases as self-government loses institutional autonomy and turns into a lower level of the management vertical. Further unification takes place within the system of local self-government and within the elements of the unified system of public authority, i.e., between municipal and regional levels of government. A simplified system of local self-government follows a single-level model, with a significant reduction in the diversity and number of municipalities, deputies, competences, etc. The chosen strategy reforms should be considered as a conscious choice by legislators of the further domestic self-government development. The strategy abandons the principle of unconditional transit to democratic institutions and turns to a model that includes the current socio-economic, political, and cultural realities of Russia.
Virulence markers, adhesion and biofilm formation of Escherichia coli strains isolated from drinking water supplies of north Paraná State, Brazil
Authors: Schüroff Paulo Alfonso , Andrade Fernanda Batista , Pelayo Jacinta Sanchez 
Published: August 2022

Abstract
Waterborne diseases are a major public health problem responsible for a high number of deaths worldwide, of which Escherichia coli is a major agent of contamination. This study investigates the occurrence of different diarrheagenic E. coli (DEC) pathotypes and its relationship with adherence patterns and biofilm formation. Between 2012 and 2014, a total of 1,780 drinking water samples were collected from different rural communities and urban water systems of north Paraná State. A total of 14% were positive for E. coli and 250 non-duplicate E. coli isolates were obtained. Between the E. coli isolates, 28 (11.2%) harbored DEC-associated genes, 10.7% being classified as Shiga toxin-producing E. coli (STEC), 64.3% enteroaggregative E. coli (EAEC) and 25% atypical enteropathogenic E. coli (aEPEC). The aggregative adherence (AA) was the predominant adherence pattern (84%), significantly associated with biofilm formation (p &lt; 0.0001). On the other hand, the AA pattern and biofilm formation were not significantly associated to DEC pathotypes (p &gt; 0.05). Therefore, we proposed that the AA pattern and biofilm formation in E. coli isolated from drinking water supplies could be associated with adherence and colonization of abiotic surfaces, such as pipes, leading to persistence and resistance to treatment or disinfection.
Policy effectiveness of water conflict management: A textual analysis of the Nansi Lake
Authors: Yang Dan , Ji Hanyu , Yang Danyan , Song Jiajing , Li Yan , Peng Jianhui , Xue Liuyu , Chen Zhisong 
Published: August 2022

Abstract
Global warming and social and economic development have led to conflicts over water resources that have gradually become one of the most disruptive factors in the global political landscape. Resolving international water conflicts is of great significance for maintaining the peaceful development of countries (regions). This paper considers the Nansi Lake located on the provincial border of Jiangsu and Shandong in eastern China as an example. Based on the textual analysis, this paper analyzes the specific data of the historical conflict resolution of the Nansi Lake to study the effectiveness of the management policies of water conflict in the Nansi Lake, namely administrative law enforcement, administrative consultation, civil consultation, policy regulation, and engineering measures. Furthermore, this paper also makes the following optimization recommendations for the policy of water conflict management by considering the successful circumstances for the policies to be applied: strengthen the government's deterrence in administrative law enforcement to promote the development of policies; promote administrative consultation and equal dialogue and exchanges among parties; understand the positions of the different parties in the civil consultation and ensure their independence of cooperation and analysis; improve the ability of scientific decision-making and effective operation for water administration department; strengthen construction management, especially effective supervision.
The unintended effects of inter-basin water transfer policies on corporate research and development activities
Authors: Sheng Jichuan , Xin Jing , Tang Weizong 
Published: August 2022

Abstract
Inter-basin water transfer (IBWT) policies alter the spatial distribution of water endowments and trigger changes in environmental regulation policies, which may unintentionally impact the research and development (R&D) activities in IBWT water-receiving areas. However, the existing studies failed to examine the relationship between IBWT policies and corporate R&D activities, and lacked the exploration of the micro-mechanism of IBWT's unintended impact on corporate R&D activities. Through the water delivery of China's South-North Water Transfer Project as a quasi-natural experiment, this study adopts a difference-in-differences approach to scrutinise the unintended impact of IBWT policies on corporate R&D activities. The findings show that IBWT policies can make the water a ‘resource blessing’ by directly improving the water endowment in water-receiving areas, thereby promoting corporate R&D activities. In addition, IBWT policies can also indirectly encourage local governments in water-receiving areas to strengthen the intensity of environmental regulations, ultimately promoting companies to improve R&D activities. Finally, the impacts of IBWT policies on corporate R&D activities in water-receiving areas are heterogeneous. Overall, this study contributes to understanding the complicated relationship between IBWT policies and corporate R&D activities, and provides insights into how IBWT policies affect corporate R&D activities.
App-Based Evaluation of Older People’s Fall Risk Using the mHealth App Lindera Mobility Analysis: Exploratory Study
Authors: Strutz Nicole , Brodowski Hanna , Kiselev Joern , Heimann-Steinert Anika , Müller-Werdan Ursula 
Published: August 2022

Background
Falls and the risk of falling in older people pose a high risk for losing independence. As the risk of falling progresses over time, it is often not adequately diagnosed due to the long intervals between contacts with health care professionals. This leads to the risk of falling being not properly detected until the first fall. App-based software able to screen fall risks of older adults and to monitor the progress and presence of fall risk factors could detect a developing fall risk at an early stage prior to the first fall. As smartphones become more common in the elderly population, this approach is easily available and feasible.

Objective
The aim of the study is to evaluate the app Lindera Mobility Analysis (LIN). The reference standards determined the risk of falling and validated functional assessments of mobility.

Methods
The LIN app was utilized in home- and community-dwelling older adults aged 65 years or more. The Berg Balance Scale (BBS), the Tinetti Test (TIN), and the Timed Up & Go Test (TUG) were used as reference standards. In addition to descriptive statistics, data correlation and the comparison of the mean difference of analog measures (reference standards) and digital measures were tested. Spearman rank correlation analysis was performed and Bland-Altman (B-A) plots drawn.

Results
Data of 42 participants could be obtained (n=25, 59.5%, women). There was a significant correlation between the LIN app and the BBS (r=–0.587, P<.001), TUG (r=0.474, P=.002), and TIN (r=–0.464, P=.002). B-A plots showed only few data points outside the predefined limits of agreement (LOA) when combining functional tests and results of LIN.

Conclusions
The digital app LIN has the potential to detect the risk of falling in older people. Further steps in establishing the validity of the LIN app should include its clinical applicability.

Trial Registration
German Clinical Trials Register DRKS00025352; https://tinyurl.com/65awrd6a
Three Times Weekly Dosing of Daprodustat versus Conventional Epoetin for Treatment of Anemia in Hemodialysis Patients
Authors: Coyne Daniel W. , Singh Ajay K. , Lopes Renato D. , Bailey Christine K. , DiMino Tara L. , Huang Chun , Connaire Jeffrey , Rastogi Anjay , Kim Sung-Gyun , Orias Marcelo , Shah Sapna , Patel Vickas , Cobitz Alexander R. , Wanner Christoph 
Published: August 2022

Background and objectives
Daprodustat is a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) being investigated for the treatment of anemia of CKD. In this noninferiority trial, we compared daprodustat administered three times weekly with epoetin alfa (epoetin) in patients on prevalent hemodialysis switching from a prior erythropoiesis-stimulating agent (ESA).

Design, setting, participants, & measurements
Patients on hemodialysis with a baseline hemoglobin of 8–11.5 g/dl receiving an ESA were randomized 2:1 to daprodustat three times weekly (n=270) or conventional epoetin (n=137) for 52 weeks. Dosing algorithms aimed to maintain hemoglobin between 10 and 11 g/dl. The primary end point was mean change in hemoglobin from baseline to the average during the evaluation period (weeks 28–52). The principal secondary end point was average monthly intravenous iron dose. Other secondary end points included BP and hemoglobin variability.

Results
Daprodustat three times weekly was noninferior to epoetin for mean change in hemoglobin (model-adjusted mean treatment difference [daprodustat-epoetin], −0.05; 95% confidence interval, −0.21 to 0.10). During the evaluation period, mean (SD) hemoglobin values were 10.45 (0.55) and 10.51 (0.85) g/dl for daprodustat and epoetin groups, respectively. Responders (defined as mean hemoglobin during the evaluation period in the analysis range of 10 to 11.5 g/dl) were 80% in the daprodustat group versus 64% in the epoetin group. Proportionately fewer participants in the daprodustat group versus the epoetin group had hemoglobin values either below 10 g/dl or above 11.5 g/dl during the evaluation period. Mean monthly intravenous iron use was not significantly lower with daprodustat versus epoetin. The effect on BP was similar between groups. The percentage of treatment-emergent adverse events was similar between daprodustat (75%) and epoetin (79%).

Conclusions
Daprodustat was noninferior to epoetin in hemoglobin response and was generally well tolerated.

Clinical Trial registry name and registration number:
Anemia Studies in Chronic Kidney Disease: Erythropoiesis via a Novel Prolyl Hydroxylase Inhibitor Daprodustat–Three Times Weekly Dosing in Dialysis (ASCEND-TD), NCT03400033
Arabic-Java Writing System: How Javanese Language Adopts Arabic Script
Authors: Jamalin Fakron , Rahman Asma Abdul 
Published: August 2022

Borrowing script happens throughout history of languages. Long before we know Latin script, Javanese has already adopted Arabic script. However, Java language deals with problematic adaptation due to distinctive sound system among those two languages, Arabic and Java. For that matter, this research aims to uncover 1) how Arabic-Java orthography represents Javanese’s consonants and vowel, and 2) how Arabic-Java orthography represents Javanese’s cluster. This research uses qualitative descriptive method. Data contain with the Javanese words which is written in Arabic script. Data are gained from eight different books which are inscribed by Arabic-Java orthography. After data are collected, the orthography method and grapheme-phoneme correspondence are used to analyze them. Grapheme-phoneme correspondence used to know how Arabic-Java orthography represents consonants and vocal phonemes. Finally, this research found that Arabic-Java orthography has 28 graphemes which are used to represent 23 consonants. Modification letters and digraph are used to represent missing sound in Arabic. Six Javanese vocals are represented with 9 graphemes. In another hand, cluster is written in two ways, first by adding Anaptyxis schwa [ə] in between sonorant-sonorant or obstruent-sonorant and vowel [a] in initial cluster nasal consonant and plosive consonant.
STUDI KEANEKARAGAMAN CAPUNG (ODONATA) SEBAGAI BIOINDIKATOR KUALITAS AIR SUNGAI BRANTAS BATU-MALANG DAN SUMBER BELAJAR BIOLOGI
Authors: Virgiawan Candra 
Published: August 2022

ABSTRAKJenis penelitian yang digunakan adalah penelitian deskriptif kuantitatif. Penelitian deskriptif bertujuan untuk mendeskripsikan suatu peristiwa dan kejadian yang terjadi, penelitian kuantitatif bertujuan untuk menjelaskan angka-angka data analisis mengunakan statistik. Penelitian ini dilakukan pada tanggal 25 Juli-16 Agustus 2014 pagi hari dengan metode jelajah (visual day flying). Data dikumpulkan dengan melakukan observasi atau pengamatan langsung terhadap populasi yang diselidiki. Berdasarkan hasil penelitian didapatkan sepuluh jenis spesies capung (Odonata), delapan jenis termasuk dalam sub ordo Anisoptera, Famili Libellulidae yaitu Diplacodes trivalis, Neurothemis ramburii, Orthetrum glaucum, Orthetrum pruinosum, Orthetrum sabina, Pantela flavescens, Trithemis festiva, Zyxomma obtusum, dan dua jenis termasuk dalam subordo Zygoptera, Famili Chlorocyphidae yaitu. Libellago lineate dan famili Coenagrionidae yaitu Ischnura sinegalensis. Odonata yang memiliki indeks nilai penting tertinggi yaitu 1.80% dari famili Libelludae, Genus Orthetrum, dan jenis Orthetrum Sabina. Nilai keanekaragaman tertinggi terdapat pada lokasi A yaitu 1.62. Nilai indeks kemerataan disemua lokasi mendekati 1 menunjukkan bahwa kondisi habitat pada semua stasiun penelitian adalah heterogen. Berdasarkan hasil analisis korelasi terdapat beberapa faktor abiotik yang memiliki korelasi yang kuat dengan jumlah jenis capung yang di temukan, faktor abiotik tersebut diantaranya adalah intensitas cahaya, DO, dan BOD. Hasil analisis FBI (Famili Biotik Indeks) diperoleh nilai 7,00, hal ini menunjukan bahwa kualitas air sungai Brantas Batu-Malang tergolong dalam kategori buruk dengan tingkat pencemaran terpolusi sangat banyak.Kata Kunci: Odonata,Sungai Brantas, Keanekaragaman jenis
Koordinasi Supply Chain Satu Pabrik-Satu Distributor pada Model Penentuan Harga dan Keputusan Produksi
Authors: Yuliawati Evi 
Published: August 2022

Competition and global market induce enterprises to meet their customer needs on product/ service in considerably cheap price, in acceptable quality and within short lead time. This leads to the fact that coordination in a supply chain is extremely important. This research compare an one manufacturer-one distributor supply chain coordination scenarios in a model joint pricing and production/order decisions. Model joint pricing and production/order decisions is based on Non Linear Programming with objective function to maximize its supply chain profit.Pricing scheme is initiated when the manufacturer determines its selling price. A supply chain coordination scenario and supply chain without coordination scenario will compare in this research. Experiment by employing a set of numerical example is performed to evaluate the model performance. Moreover, sensitivity analysis is done to explore the effect of capacity’s and price to demand sensitivity-parameter’s changes to the objective function of proposed model.
An Analysis of a Transformerless Dual Active Half-Bridge Converter
Authors: Sosnowski Robert , Chojowski Maciej , Baszyński Marcin 
Published: August 2022

Abstract
This paper proposes a transformerless dual half-bridge converter (TLDAHB). By eliminating the transformer and harnessing the possibility of using a low inductor value, it is possible to minimise the size of the converter. A phase-shift pulse width modulation will result in a wide controlled voltage gain of the converter and operation as buck and boost. The theoretical topology analysis, simulation, and experimental results are presented. Theoretical analysis consists of analysis of power transfer and design. In case of experimental research, particular attention was paid to power transfer and efficiency analysis. Near zero switching transient of voltage in the half-bridge topology results with high efficiency.