bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Adverse Effect of Diclofenac Exposure during Pregnancy on Mother and Fetus; A Systematic Review
Authors: Handiso Tilahun Beyene , Bachore Bahailu Balcha , Hagisso Shemsu Nuriye , Jifar Markos Selamu 
Published: May 2022

Abstract
Introduction: Since 1974, diclofenac has been used to treat the pain and swelling associated with rheumatic illnesses as a non-steroid anti-inflammatory medication (NSAID). It is one among the world's most extensively used non-steroidal anti-inflammatory medications (NSAIDs). Non-steroidal anti-inflammatory medicines have been shown to cause embryotoxicity and teratogenicity in experimental animals in a few studies, however there is no strong evidence of this impact in people.The aim of this study was to conduct a systematic assessment of the effects of diclofenac exposure on the mother and fetus during pregnancy.Methods: This study included all experimental, quasi-experimental, and observational research that were published in the English language and published up to the date of the review. PROSPERO (The International Prospective Register of Systematic Reviews) ID = CRD42019135608 was used to register the protocol. This study employed a three-step search technique. PubMed, Medline, SCOPUS, Web of Science, Embase, cinihal, Google, several university repositories, and Google scholar were among the databases searched. The titles and abstracts were then examined by two independent reviewers to see if they met the review's inclusion criteria. At the study level, two independent reviewers critically assessed eligible studies. The review's methodological quality was assessed at the result level using standardized critical assessment instruments from the Joanna Briggs Institute (JBI) for observational studies. Specific details about the demographics, study procedures, interventions, and outcomes of significance to the review purpose are included in the data retrieved from the studies. Due to the conclusion and type of the data, statistical pooling was not viable. As a result, the results were presented in a narrative format.Results: A total of 1,490,679 participants were found in three relevant papers (two cohorts and nested case-control studies). Diclofenac exposure during pregnancy raises the chance of low birth weight in the fetus, as well as the risk of spontaneous abortion and vaginal bleeding in the mother.Conclusions: Diclofenac exposure during pregnancy has negative consequences on the fetus and the mother. As a result, taking Diclofenac during pregnancy may have negative consequences for both the mother and the fetus, and more primary Randomized Control Trials (RCTs) are needed.
Ancient impact-scars control regional geology worldwide
Authors: Saul John M. 
Published: May 2022

Abstract
Bombardment of the Earth at an early date established initial conditions that have affected all later regional geology. No part of the Earth's crust escaped. Activity at the brittle-ductile boundary has caused large-diameter scars to be sporadically regenerated upward throughout the four-billion years of our planet's history. Although these three-dimensional 'craterform' scars have evolved in many different manners, and many are covered over at any given time, many retain observable two-dimensional map-outlines with circular curvature. These inherited scar-features have been regenerated 'cold' from below and are fundamentally different from 'astroblemes', as presently defined, whose constituent rocks had been directly subjected to the high temperatures and pressures that accompany extra-terrestrial impacts. The varied present-day manifestations of these scars need to be described and categorized as has been done for faults, folds, rocks, and minerals by earlier workers in the earth sciences.
An Updated Systematic Review and Meta-Analysis of The Safety and Efficacy of Factor Xa Inhibitors Versus Low Molecular Weight Heparin Therapy for Treatment of Cancer Associated Venous Thromboembolism
Authors: Qurashi Abdullah A. Al , Albeirouti Rasana B. , Kamal Omar J. , Alsaidlani Rawan H. , Huzali Abdullah Al , Kuwaity Lamar Hattan , Alnafisi Aasal Ahmed , Albeirouti Bassim T 
Published: May 2022

Abstract
Background
Patients with cancer-related venous thromboembolism (CA-VTE) have discovered Factor Xa inhibitors to be an effective intervention in recent decades. However, the greater bleeding risk involved with Factor Xa inhibitors than with low molecular weight heparin (LMWH) has now been substantiated in non-randomized studies as well as randomized control trials (RCT), albeit ambiguously, and this raises concerns for patients with CA-VTE.
Aims
We aim to pool data from all relevant studies reporting results for recurrent VTE, bleeding and mortality related to bleeding in CA-VTE patients undergoing treatment with Factor Xa inhibitors versus LMWH.
Methods
PubMed and Scopus databases were queried from inception through last week of March, 2022 for all RCT and non-randomized studies comparing the efficacy of Factor Xa inhibitors versus LMWH in patients with CA-VTE, on recurrence of VTE, clinically relevant non-major bleeding (CRNMB) and major bleeding events and mortality related to bleeding. A random-effects model was used and risk ratios (RR) with 95% confidence intervals (CI) were reported.
Results
Fourteen non-randomized studies and six RCTs were included in our analysis. The total participants were 17,781. Our pooled analysis demonstrated that in non-randomized studies, Factor Xa inhibitors, compared to LMWH, had a significantly lower risk of recurrence of VTE (RR: 0.70 [0.60, 0.80]; p = 0.00001; I2 = 0%) and a significantly higher risk of overall bleeding (RR: 1.51 [1.10, 2.07]; p = 0.01; I2 = 59%), however, no significant difference in the risk of bleeding-related mortality was observed between Xa inhibitors and LMWH (RR: 0.99 [0.34, 2.92]; p = 0.99; I2 = 0%). In RCTs, Factor Xa inhibitors, compared to LMWH, had a significantly lower risk of recurrence of VTE (RR: 0.65 [0.49, 0.85]; p = 0.002; I2 = 3%) and a significantly higher risk bleeding (RR: 1.35 [1.02, 1.80]; p = 0.04; I2 = 37%). However, no significant difference in the risk of bleeding-related mortality was observed between Factor Xa inhibitors and LMWH (RR: 0.33 [0.07, 1.43]; p = 0.14; I2 = 0%). Furthermore, our pooled analysis demonstrated that there was no significant difference in the risk of overall bleeding in GI malignancies, between Factor Xa inhibitors and LMWH (RR: 1.39 [0.86, 2.26]; p = 0.18; I2 = 58%), risk of CRNMB (RR: 1.52 [0.80, 2.88]; p = 0.20; I2 = 56%), and the risk of major bleeding (RR: 1.29 [0.66, 2.48]; p = 0.46; I2 = 46%).
Conclusion
Our results show that in the context of CA-VTE, Factor Xa inhibitor therapy may be a safe, effective, and realistic alternative to LMWH.
Angiolipoma tissue analysis based on color-based segmentation using L * a * b * color space
Authors: Radak Mahyar 
Published: May 2022

Abstract
Texture analysis refers to the description of areas in an image with their texture content. Texture analysis attempts to determine visual qualities described in terms such as rough, smooth, silky, or uneven as a function of spatial variations in pixel intensity. This article shows how to identify different colors in angiolipoma tissue by analyzing the color space L * a * b *. Texture analysis can be useful when objects are identified more closely by their texture in an image than by intensity, and traditional thresholding techniques can not be used effectively.
Polemical duel on the «Open field of historical facts»
Authors: Рыбаков С.В. 
Published: May 2022

Статья посвящена журнальной полемике между Т.Н. Грановским и А.С. Хомяковым, состоявшейся в 1847 г. Несмотря на незначительный повод к ее началу, она высветила методологические и методические различия в подходах к изучению истории со стороны двух известных общественных деятелей середины XIX в., один из которых представлял умеренное западничество, а другой – славянофильство. Эта полемика наглядно отразила уровень развития тогдашней исторической науки.
The article is devoted to the magazine controversy between T. N. Granovsky and A. S. Khomyakov, which took place in 1847. Despite the insignificant reason for its beginning, this controversy highlighted the differences in the theory and methods of studying history on the part of two well-known public figures of the middle of the XIX century, representing respectively enlightened Westernism and Slavophilism. The controversy between them reflected the level of development of historical science at that time.
From the History of French Hellenistic Studies
Authors: Маргарян Е.Г. 
Published: May 2022

За последние полтора века французская историография эллинизма прошла несколько этапов развития, обусловленных, прежде всего, политической конъюнктурой. Первая половина ХХ в. прошла под лозунгами «благотворного империализма», при-званными легитимировать колониальную политику ведущих империй Нового времени. Крушение империй и колониальной системы породило новое отношение к ис-стории эллинизма. Постколониальный дискурс лишил Александра и греко-македон-ские империи героического ореола и позволил взглянуть на эллинизм с точки зрения коренных жителей Передней и Центральной Азии, а также ориентализированных греков, ставших частью нового для них мира. Новый дискурс открыл новые перспективы для изучения истории эллинизма, но вместе с тем потребовал обогатить исследовательскую палитру новыми методами. В частности – микроисторией, т.к. именно этот метод позволяет наиболее полно осветить историю «безмолствующего большинства» коренного населения, завоеванных македонцами стран.
Over the past century and a half, the French historiography of Hellenism has passed through several stages of development, primarily due to the political situation. The first half of the twentieth century was spent under the slogans of "beneficial imperialism", designed to legitimize the colonial policy of the leading empires of Modern times. The collapse of empires and the colonial system gave rise to a new attitude to the history of Hellenism. Postcolonial discourse deprived Alexander and the Greek-Macedonian empires of the heroic aura and allowed them to look at Hellenism from the point of view of the indigenous inhabitants of the Front and Central Asia, as well as the orientalized Greeks who became part of a new world for them. The new discourse opened up new perspectives for studying the history of Hellenism, but at the same time demanded to enrich the research palette with new methods. In particular, microhistory, because this method allows you to most fully cover the history of the" silent majority" of the indigenous population of the countries conquered by the Macedonians.
The Tatars’ Image and Self-consciousness of the North-Eastern Rus’ Bookmen During Ivan the Great’s Reign
Authors: Гребенников Н.Ю. 
Published: May 2022

В статье представлен анализ известий сводов северо-восточной летописной традиции, которые составлялись при жизни Ивана III. Сведения, содержащиеся в них, предоставляют прекрасную возможность понять, как древнерусские книжники воспринимали «разных» татар и предположить возможные истоки соответствующего отношения. Более того, четкое разграничение на «русь»/«татары», которое проводят летописцы в текстах, позволяет определить главные «составляющие» самосознания книжников и выстроить их в некую иерархию в зависимости от значимости каждой.
The paper focuses on scrutinizing some chronicle reports of the North-Eastern chronicles, were being composed during Ivan the Great’s life. The evidences which they contain are significantly important for understanding the perception of bookmen towards the different groups of the Tatars and further reconstructing of their images as well. Moreover, the strictly distinguishing between the Tatars and Rus’, which is drawn by Old-Russian chroniclers in chronicle texts, allows to reveal the primary elements of bookmen’ self-consciousness and to ascertain place for each of them in the hierarchy, crucial for Rus’ self-consciousness.
The Muslims of Pre-colonial India: Historical Narratives and Self-Identification
Authors: Ванина Е.Ю. 
Published: May 2022

Статья рассматривает исторические нарративы Делийского султаната и Могольской империи в контексте самоидентификации мусульман. Если ранние хроники утверждали единственную идентичность мусульман – конфессиональную, требовавшую борьбы с «неверными», то в процессе территориально-культурной адаптации часть их стала позиционировать себя как жителей Индии, имеющих общую родину, культуру и историческое прошлое с местными индусами. В эпоху Моголов мусульманские и индусские авторы сконструировали общеимперский исторический дискурс, подчеркивающий лояльность власти как надконфессиональную ценность. Вместе с тем, тенденция чисто конфессиональной, неиндийской самоидентификации сохранилась и в колониальные времена стала основой мусульманского национализма.
The paper discusses historical narratives of the Delhi sultanate and Mughal empire vis-à-vis Muslim self-identification. While the early chronicles established exclusively confessional identity of Muslims and glorified struggle against the ‘infidels’, the process of adaptation made a considerable part of Muslims position themselves as inhabitants of India sharing homeland, culture and, importantly, historical past, with local Hindus. In the Mughal epoch, Muslim and Hindu authors jointly constructed an imperial historical discourse highlighting loyalism as supra-communal value. At the same time, the tendency towards communal ‘un-Indian’ self-identification of Muslims has also been in force, to become, in colonial times, the basis for Muslim nationalism.
From the People to Citizenship: the Problem of Constructing Polish Historical Narrative in the 18th-19th Centuries
Authors: Басов И.М. 
Published: May 2022

Статья рассматривает процесс трансформации этногенетических и сословных категорий в модерные национальные на примере польского Просвещения и романтического национализма. Прочтение исторических источников XVI-XVII вв., на которые ориентировались творцы польского национального проекта, обнаруживает несоответствие фундаментальных понятий. Однако несоответствие остается незамеченным на протяжении всего XIX в. Это повод задаться вопросами: почему конструирование исторического нарратива не встретило препятствия в лице исторических источников, и как национальному нарративу удалось примирить сословное прошлое с эгалитарной идеей гражданской нации?
The article considers the process of transformation of ethnogenetic and estate categories into modern national ones using the example of the Polish Enlightenment and romantic nationalism. Reading the historical sources of the 16th–17th centuries, which ideologists of the Polish national project were guided by, reveals an inconsistency in the framing of fundamental concepts. However, the inconsistency remained unnoticed by the masterminds of the national project in the 19th century. This is a reason to ask the question: why was the construction of a historical narrative not hindered by historical sources, and how did the national narrative manage to reconcile the estate past with the egalitarian idea of a civil nation?
The State, Society and Philately in the Soviet Reality of the First Half of the 1920s, or How they Fought Against Postal Fraud and Fiction
Authors: Якуб А.В. 
Published: May 2022

Рассматривается политика советского руководства в области защиты государственного интереса в сфере почты и филателии как внутри страны, так и за рубежом, связанного с увеличением количества фальшивых и фантастических знаков почтовой оплаты. Выделяются два основных периода в этой деятельности: «оборонительный» (1917–1921) и «контрнаступательный» (1922–1925). Характеризуются основные механизмы, методы и средства в борьбе с изготовлением фальшивых почтовых марок с целью защиты политико-экономических интересов страны, особенно за рубежом, и интересов отдельных коллекционеров.
The article considers the policy of the Soviet leadership in the field of protecting the state interest in the field of mail and philately both at home and abroad, associated with an increase in the number of fake and fantastic postage stamps. There are two main periods in this activity: "defensive" (1917-1921) and "counter-offensive" (1922-1925). The main mechanisms, methods and means in the fight against the production of counterfeit postage stamps in order to protect the political and economic interests of the country, especially abroad, and the interests of individual collectors are characterized.
Inclusive WASH and sustainable tourism in Labuan Bajo, Indonesia: needs and opportunities
Authors: Dwipayanti Ni Made Utami , Nastiti Anindrya , Johnson Helen , Loehr Johanna , Kowara Mellysa , de Rozari Philippi , Vada Sera , Hadwen Wade , Nugraha Mariano A. T. , Powell Bronwyn 
Published: May 2022

Abstract
Rapid tourism growth can place unprecedented strain on water resources and reduce access for local communities. This study explored the state of Inclusive water, sanitation and hygiene (WASH) in the tourism sector and local communities of Labuan Bajo, one of Indonesia's ‘super-premium’ tourism destinations. The formative research applied an Inclusive WASH-at-Work framework; data were collected using a case study methodology through semi-structured interviews (n = 20) and focus groups (n = 6) with government, tourism and community stakeholders. The findings identified growing tensions over inequitable water service levels and WASH access. Significantly, reported negative impacts were disproportionately experienced by women and girls, elderly and disabled members of the community, who suffer most from inadequate WASH facilities in hotels, public settings and their homes. Governance of and capacity constraints around WASH management highlighted the value of Inclusive WASH solutions to overcome the challenges Labuan Bajo faces as a rapidly developing tourism destination. Critically, solutions must be locally-driven, build local capacity and open pathways to collaboration between the community and decision-makers in the national government, provincial government and private tourism sector. Enhanced stakeholder collaboration and increased private sector contributions are needed to ensure a more equitable distribution of tourism benefits to underpin WASH and destination sustainability.
Operationalizing irrigation water charges in sub-Saharan Africa: a case study from the Central Rift Valley, Ethiopia
Authors: Hagos Fitsum , Ahmed Jemal , Haileslassie Amare , Seid Abdulkarim 
Published: May 2022

Abstract
Fixing and implementing water charges in the irrigation sector is considered an important task for recovering operation and maintenance costs and promoting the efficient use of water. This study aims at developing an implementation strategy for water charges in the Central Rift Valley, Ethiopia. The study sets the agenda for this strategy by explaining why promoting the concept of fixing irrigation charges is necessary. Then it develops a conceptual framework, draws key lessons from global experiences, explores whether the new pricing policy is well aligned with national water policies and the roles and responsibilities of various actors and stakeholders involved, and identifies the factors for the successful implementation of this strategy. The study is mainly qualitative in nature, based on a review of the literature and consultations of key stakeholders. The study results call for clearly defining the key objectives of the policy, political commitment, and community participation, re-examining the role of institutions, capacity building, and establishing a multistakeholder platform. Basin-level implementation of this policy requires piloting and maintaining policy dynamics through adaptive management. The results provide generic lessons for other basins within Ethiopia and for sub-Saharan Africa (SSA).
Community Health Worker-Led mHealth-Enabled Diabetes Self-management Education and Support Intervention in Rural Latino Adults: Single-Arm Feasibility Trial
Authors: Li Shiyu , Yin Zenong , Lesser Janna , Li Chengdong , Choi Byeong Yeob , Parra-Medina Deborah , Flores Belinda , Dennis Brittany , Wang Jing 
Published: May 2022

Background
Latinos living in rural South Texas have a higher prevalence of diabetes, but their access to diabetes self-management education and support (DSMES) is limited.

Objective
We aimed to test the feasibility of a community health worker-led, mobile health (mHealth)-based DSMES intervention to reduce disparities in accessing DSMES in underserved rural Latino residents in South Texas.

Methods
This 12-week, single-arm, pre-post trial was delivered by trained community health workers to 15 adults with type 2 diabetes. The intervention consisted of digital diabetes education, self-monitoring, a cloud-based connected platform, and community health worker support. Feasibility was evaluated as retention, actual intervention use, program satisfaction, and barriers to implementation. We also explored the intervention’s effect on weight loss and hemoglobin A1c (HbA1c).

Results
All 15 participants were Latino (mean age 61.87 years, SD 10.67; 9/15 female, 60%). The retention rate at posttest was 14 of 15 (93%). On average, the participants completed 37 of 42 (88%) digital diabetes education lessons with 8 participants completing all lessons. Participants spent 81/91 days (89%) step tracking, 71/91 days (78%) food logging, 43/91 days (47%) blood glucose self-monitoring, and 74/91 days (81%) weight self-monitoring. The level of program satisfaction was high. On average, participants lost 3.5 (SD 3.2) kg of body weight (P=.001), while HbA1c level remained unchanged from baseline (6.91%, SD 1.28%) to posttest (7.04%, SD 1.66%; P=.668).

Conclusions
A community health worker-led mHealth-based intervention was feasible and acceptable to improve access to DSMES services for Latino adults living in rural communities. Future randomized controlled trials are needed to test intervention efficacy on weight loss and glycemic control.