bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Integrated 31-Gene Expression Profile (i31-GEP) Test for Cutaneous Melanoma Outperforms a Clinicopathologic-only Nomogram at Identifying Patients who can Forego Sentinel Lymph Node Biopsy
Authors: Zakria Danny , Brownstone Nicholas , Rigel Darrell 
Published: November 2022

Introduction: National guidelines for cutaneous melanoma suggest avoiding sentinel lymph node biopsy (SLNB) if the risk of SLN positivity is <5% (T1a with no high-risk features), considering SLNB if the risk is 5-10% (T1a with additional high-risk features (T1aHR) and T1b), and offering SLNB if the risk is >10% (T2-T4). Because most patients (88%) who undergo an SLNB have a negative result, novel tools to identify patients who can safely forgo SLNB are critical. The integrated 31-gene expression profile (i31-GEP for SLNB) test for cutaneous melanoma combines tumor molecular biology with clinicopathologic features to provide a precise risk of SLN positivity. The Melanoma Institute of Australia (MIA) developed a nomogram that uses only clinicopathologic features to predict SLN positivity.
Methods: We compared the i31-GEP for SLNB to the MIA nomogram in patients with T1-T2 tumors with complete data (n=582). The precision of each tool to identify patients with <5% SLN positivity risk was analyzed using 95% confidence intervals. To be considered low risk, the predicted risk must be <5% and the upper 95% confidence interval must be ≤10%, and to be considered high-risk, the predicted risk must be >10% and the lower 95% CI ≥5%.
Results: The i31-GEP for SLNB identified 28.5% (166/582) of patients as having a <5% risk of SLN positivity while also having an upper 95% CI ≤10% compared with 0.9% (5/582, p<0.001) using the MIA nomogram. In patients with a pre-test likelihood of SLN positivity of 5-10% (T1aHR-T1b), the i31-GEP reclassified risk in 60.2% (171/284) of patients as being <5% or >10% compared to 13.7% (39/284, p<0.001) using the MIA nomogram. In patients with a known SLN status (n=466), the i31-GEP for SLNB identified 22.1% (103/466) of patients as having <5% risk, with a 3.9% (4/103) SLN positivity rate compared to 0.6% (3/466, p<0.001) identified by the MIA as having a <5% risk with a 33.3% (1/3) SLN positivity rate.
Conclusions: The i31-GEP test outperformed the MIA nomogram in identifying patients who could safely forego SLNB. Integrating the 31-GEP molecular risk stratification tool with clinicopathologic features provides precise SLN positivity risk to better guide patient management in patients with T1-T2 tumors, for whom SLNB guidance could be most impactful.
Support Group Utilization and Perspectives Among Hidradenitis Suppurativa Patients
Authors: De Devea , Shih Terri , Atluri Swetha , Fixsen Denise , Brooks Brindley , Hsiao Jennifer , Shi Vivian 
Published: November 2022

Introduction: Hidradenitis suppurativa (HS) is a chronic inflammatory dermatosis associated with significant psychosocial burden. HS patients are more likely to experience mental health comorbidities such as depression and anxiety. They may also experience isolation due to fear of stigmatization as HS lesions are often associated with pain, scarring, and odor. This study investigates the perspectives of HS patients on HS support groups and the usage of this resource among this population.
Methods: An anonymous Redcap survey was utilized via online social media HS support groups between 10/2021-1/2022 to collect demographic, usage, and perspective data. Comparative statistics were conducted and p-value of <0.05 was considered significant.
Results: Of the 166 respondents, 78% respondents were part of an HS support group however, only 12% of respondents were recommended to join by their main HS healthcare provider and most (68%) learned about support groups through their own internet searches. Most respondents were daily (42%) and weekly (38%) support group users. Virtual meetings were preferred by the majority compared to in person meetings (50% vs 13%). The top reasons respondents reported attending support groups were to better understand HS, increasing their knowledge of HS resources, and access to treatment/care tips. Respondents without dermatologists as their main HCP and skin of color (SOC) respondents were more likely to report that support groups improved their care of HS (4.29 vs 3.90, p=0.031).
Conclusion: Our findings highlight the preferential format of virtual support groups and that support groups may be an underutilized resource by healthcare providers for their patients. Support groups may help to narrow gaps in education when patients are unable to access or have delays in obtaining dermatological care, especially in SOC patients who have historically experienced higher rates of healthcare disparities.
CRITERIA OF PROFESSIONAL COMPETENCE OF EMPLOYEES OF CRIMINALLY-EXECUTIVE SYSTEM
Authors: Копылова Наталья Вячеславовна , Копылова Юлия Алексеевна 
Published: November 2022

Рассмотрена профессиональная компетентность сотрудников уголовно-исполнительной системы. С целью ее оценки нами была разработана и апробирована «Карта критериев профессиональной компетентности сотрудников УИС», позволившая выделить ряд наиболее значимых критериев.
The article examines the professional competence of the employees of criminally-Executive system. In order to evaluate it, we have developed and tested the "Map of criteria for the professional competence of employees of the UIS", which allowed us to identify a number of the most significant criteria.
PSYCHOLOGICAL ASPECTS OF THE EFFICIENCY OF THE MANAGEMENT IN EXTREME MANAGEMENT SITUATIONS
Authors: Посохова Анастасия Владиславовна , Жемерикина Юлия Игоревна 
Published: November 2022

Рассмотрены психологические факторы, способствующие повышению эффективности деятельности руководителя в экстремальных управленческих ситуациях. Обосновано понятие экстремальных управленческих ситуаций. Показано, что управленческая деятельность в них является сложно-совмещенной. Установлено, что многие руководители в силу недостатка профессионализма являются своеобразными «генераторами» экстремальных управленческих ситуаций.
The paper considers the psychological factors that contribute to improving the efficiency of the leader in extreme management situations. The concept of extreme management situations is substantiated, it is shown that management activity is complex-combined in it. It has been established that many managers, due to lack of professionalism, are a kind of "generators" of extreme managerial situations.
FACTOR STRUCTURE OF REPRESENTATIONS ABOUT THE REASON FOR SEEKING COUNSELING AMONG PEOPLE WITH DIFFERENT RELIGIOUS IDENTITY
Authors: Чибисова Марина Юрьевна , Белая Анна Константиновна 
Published: November 2022

Представлены результаты исследования изучения представлений о причинах обращения за психологической помощью у респондентов с различной выраженностью религиозной идентичности. В рамках исследования разработан авторский опросник «Ситуации обращения за психологической помощью». Подвергнутые факторному анализу результаты позволили нам выявить, что структура представлений о возможных причинах обращения к психологу у респондентов с высокой выраженностью религиозной идентичности включает факторы «дисфункциональные близкие отношения», «личные эмоциональные трудности», «психологическая несостоятельность», «самоопределение», «вера и религия»; у респондентов со средней выраженностью религиозной идентичности факторы «отношения со значимыми другими», «экзистенциальные и личностные вопросы», «выбор и доверие», «болезни», «девиантные проявления»; у респондентов с низкой выраженностью религиозной идентичности факторы «проблемы психологического характера», «вера и религия», «невозможность иметь детей».
This article presents the results of a pilot and main thesis research, the purpose of which was to study the factor structure of representations about the reasons for applying for psychological assistance among respondents with different religious identity intensity. As part of the study the author's questionnaire «Situations of applying for psychological assistance» was developed. Subjected to factor analysis, the results obtained during the author's questionnaire allowed us to reveal that the structure of ideas about the possible reasons for contacting a psychologist among respondents with high intensity of religious identity includes factors «dysfunctional close relationships», «personal emotional difficulties», «psychological inferiority», «self-determination», «faith and religion»; for respondents with an average intensity of religious identity - the factors «problems in emotionally close relationships», «existential and personal issues», «choice and trust»,»diseases», «deviant manifestations»; respondents with a low intensity of religious identity have the factors «problems of a psychological nature», «faith and religion», «impossibility to have children».
FEATURES OF CONSTRUCTIVE INTERACTION OF STUDENTS AND TEACHERS IN EDUCATIONAL SPACE OF THE COLLEGE
Authors: Кусакина Елена Аркадьевна , Иванова Регина Юрьевна 
Published: November 2022

Рассматриваются особенности конструктивного взаимодействия между субъектами образовательного процесса в системе среднего профессионального образования. Представлен анализ теоретических подходов к пониманию и содержанию конструктивного взаимодействия между преподавателем и студентом. В результате эмпирического исследования, проведенного на базе КГАПОУ «Пермский строительный колледж», выявлены особенности и проблемы функционирования системы взаимоотношений между участниками образовательного процесса. В качестве стимульного материала использованы проективные методы и анкета в авторской модификации. Определена стратегия педагогического общения, преобладающий стиль общения между преподавателем и студентом, степень удовлетворенности преподавателя условиями профессиональной деятельности, психологический портрет идеального преподавателя колледжа и текущее эмоциональное состояние. Полученные результаты позволят руководству колледжа определить ключевые проблемы в организации учебно-воспитательного процесса и разработать специальные проекты по развитию конструктивного взаимодействия между участниками образовательного процесса.
The article discusses the features of constructive interaction between the subjects of the educational process in the system of secondary vocational education. An analysis of theoretical approaches to the understanding and content of constructive interaction between a teacher and a student is presented. As a result of an empirical study conducted on the basis of the Perm Construction College, the features and problems of the functioning of the system of relationships between the participants in the educational process were identified. Projective methods and a questionnaire in the author's modification were used as stimulus material. As a result of the study, the strategy of pedagogical communication, the prevailing style of communication between the teacher and the student, the degree of satisfaction of the teacher with the conditions of professional activity, the psychological portrait of the ideal college teacher and the current emotional state were determined. The results obtained will allow the college management to identify key problems in the organization of the educational process and develop special projects for the development of constructive interaction between participants in the educational process.
UNITY OF TRAINING AND EDUCATION IN ART LESSONS: PEDAGOGICAL TECHNOLOGY «IMAGE AND THOUGHT»
Authors: Казакова Ирина Борисовна , Сафонова Евгения Викторовна 
Published: November 2022

Анализируется проблема интеграции образовательных и воспитательных технологий при обучении гуманитарным дисциплинам в школе на примере технологии «Образ и мысль». Уточнены и конкретизированы такие ведущие категории исследования, как: «духовность», «духовная потребность», «художественная образность». В качестве иллюстрации применения технологии «Образ и мысль» приводятся методические рекомендации для проведения урока на тему «Интерпретация в изобразительном искусстве сюжета "Иисус Христос в доме Марфы и Марии"», объединяющую в себе религиозную, моральную, искусствоведческую и историко-культурную проблематику. Методологической основой являются системный, личностно-деятельностный и культурологический подходы. Рассмотрев особенности педагогической технологии «Образ и мысль» и возможности применения ее образовательного и воспитательного потенциала, авторы статьи пришли к выводу о целесообразности использования этой технологии при обучении гуманитарным дисциплинам, задачей которых является не только получение обучающимися конкретных знаний об истории культуры, но и формирование личности, интегрированной в духовную жизнь человеческого общества.
The article analyzes the problem of integrating educational and upbringing technologies in teaching humanitarian disciplines at school using the example of the technology «Image and Thought». Such leading categories of research as spirituality, spiritual need, artistic imagery. As an illustration of the application of the «Image and Thought» technology, provides guidelines for conducting a lesson on the topic «Interpretation in the visual arts of the plot "Jesus Christ in the House of Martha and Mary"», combining religious, moral, art history and historical cultural issues.The methodological basis is systemic, personal-activity and cultural approaches. Having considered the features of the pedagogical technology "Image and Thought" and the possibilities of using its educational and educational potential, the authors of the article came to the conclusion that it is expedient to use this technology in teaching humanities, whose task is not only to get students specific knowledge about the history of culture, but also to form a personality integrated into the spiritual life of human society.
PHASED SOLID CONSTRUCTION TASKS SOLVING METHODS
Authors: Леонтьева Наталия Владимировна 
Published: November 2022

Изучение конструктивной геометрии способствует формированию пространственного мышления, развитию математической культуры. Применение поэтапной методики даёт возможность организовать обучение школьников решению задач на построение в пространстве. Анализ работ по методике обучения геометрии позволяет выделить основные этапы и установить взаимосвязи между ними.
Constructive geometry learning promotes spatial thinking forming, mathematical culture development. Phased methods allow to organize solid constructive tasks solving teaching of students. Geometry learning methods article analysis gives the opportunity to highlight mains stages and to establish communication between its.
TRAINING AND PRE-PROFESSIONAL TRAINING IN THE CONDITIONS OF REMOTE INTERACTION
Authors: Нагорнова Алина Александровна , Царапкина Юлия Михайловна , Анисимова Алёна Вячеславовна 
Published: November 2022

Рассматривается влияние применения различных дистанционных каналов (Zoom и Яндекс.Телемост) на студентов и обучающихся. Проводится анализ дистанционных платформ обучения на основе интерактивного взаимодействия в ходе обучения и реализации мероприятий предпрофессиональной подготовки. Представлены положительные и отрицательные аспекты выбора дистанционного взаимодействия представленных сервисов. На примере платформ Zoom и «Яндекс.Телемост» изучаются вопросы влияния различных онлайн-сервисов на физическое и психологическое здоровье обучающихся.
The article discusses the process of pre-professional training using various remote various channels (Zoom and Yandex.Telemost). The analysis of distance learning platforms based on interactive interaction in professional orientation is carried out. The article presents the positive and negative aspects of the choice of remote interaction of the presented services. Using the example of the Zoom and Yandex.Telemost examines the impact of various online services on the physical and psychological health of students.
APPLICATION OF THE RESEARCH METHOD IN ENGINEERING EDUCATION
Authors: Корнеенко Татьяна Николаевна 
Published: November 2022

Последние изменения в сфере высшего образования предполагают трансформацию образовательного процесса, в частности, применяемых методов. В статье предлагается анализ исторических практик университета, на основании чего выделяются подходы к построению новых образовательных практик. Выделены основные принципы образовательной деятельности в современном университете и предложено сочетание следующих методов: метод steam-технологий, проектный метод и научно-исследовательский семинар. Представлены варианты их применения в образовательном процессе.
Changes in the field of higher education contribute to the transformation of the educational process, in particular the methods used. The article proposes an analysis of the historical practices of the university, on the basis of which approaches to the construction of new educational practices are distinguished. The main principles of educational activity at a modern university are highlighted and a combination of the following methods is proposed: the steam-technologies method, the project method and the research seminar. Variants of their application in the educational process are presented.
FORMATION OF THE REFLEXIVE COMPONENT OF THE SELF-EDUCATIONAL CULTURE OF YOUNGER SCHOOLCHILDREN
Authors: Сметанникова Юлия Игоревна 
Published: November 2022

Актуализирована проблема формирования самообразовательной культуры обучающихся в условиях начального общего образования. В центре внимания исследования - задача формирования рефлексивного компонента самообразовательной культуры младших школьников. Предложены направления и формы работы по формированию рефлексивного компонента самообразовательной культуры младших школьников. Приведены результаты опытно-экспериментальной работы, свидетельствующие о положительном влиянии предложенных направлений и форм работы на формирование самообразовательной культуры обучающихся в начальной школе.
The article actualizes the problem of formation of self-educational culture of students in the conditions of general education. The focus of this study is the task of forming a reflexive component of the self-educational culture of younger schoolchildren. The directions and forms of work on the formation of the reflexive component of the self-educational culture of younger schoolchildren are proposed. The results of experimental work are presented, indicating the positive impact of the proposed directions and forms of work on the formation of self-educational culture of students in primary school.
A cross-sectional study determining the relationship between eating and drinking skills and functional independence levels of patients with cerebral palsy
Authors: Sirzai Hulya , Dundar Emine Ahi 
Published: November 2022

Background/Aim: In cerebral palsy (CP), drinking/eating disorders are considered common. To evaluate these disorders, a very detailed and lengthy evaluation is required. Few tools are available to identify children who need to be evaluated. This study determined whether the functional independence level of children with CP is sufficient to predict their drinking/eating skills and to determine the relationship between this functional level and these skills.
Methods: A total of 105 children with CP aged 4–8 years participated in a cross-sectional study in our outpatient clinic. Functional classification was assigned using the Gross Motor Function Classification System and Manuel Ability Classification System (GMFCS and MACS, respectively). For a functional assessment of daily life, the Pediatric Evaluation of Disability Inventory (PEDI) was performed by asking a relative of the child. The Eating and Drinking Abilities Classification System (EDACS) level was added to the study after asking the caregivers of the patients for eating/drinking evaluations.
Results: According to the current results, we found a negative correlation between EDACS and PEDI scores. As the EDACS grade increased, the PEDI subscale and total scores decreased in a statistically significant manner (P < 0.001), while the GMFCS and MACS scale increased statistically (P < 0.001). As the PEDI subscale and total scores increased, the levels of GMFCS and MACS decreased statistically significantly (P < 0.001).
Conclusions: The performances of children with CP in terms of activities of daily living are closely related to their performance in eating/drinking activities. If children are independent in their mobility, social functions, and daily self-care, they are also more independent in terms of eating/drinking.
Incidence of Anxiety and Depression in Patients with Chronic Obstructive Pulmonary Disease: A Meta-Analysis
Authors: Wang Xiaotao , Lei Li , Deng Peng 
Published: November 2022

Objective: To systematically evaluate the incidence of COPD with anxiety and depression in the past 5 years.
Methods: The databases of CNKI, Wanfang, VIP, CBM, PubMed, WebofScience, TheCochraneLibrary and EMbase were searched by computer. The study type was cross-sectional study or other types of study that included baseline data. Outcome indicators included the incidence of anxiety or depression; The cross-sectional study evaluation scale recommended by AHRQ was used to evaluate the quality of the included literature, and StataSE 16 was used to complete the meta-analysis.
Results: A total of 35 literatures were included, including 27 Chinese literatures and 9 English literatures. Meta-analysis results showed that: The overall incidence of COPD combined with anxiety or depression was 50.00%, the overall incidence of COPD combined with anxiety was 40%, the incidence of COPD combined with depression was 42%, and the incidence of COPD combined with anxiety and depression was 20%.
Conclusion: The incidence of COPD combined with anxiety and depression is high. Clinicians and patients' families should pay attention to COPD, and the psychological problems of patients, and prevent the occurrence of anxiety and depression.