bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polypropylene pyrolysis kinetics under isothermal and non-isothermal conditions: a comparative analysis
Authors: Nisar Jan , Khan Muhammad A. , Ali Ghulam , Iqbal Munawar , Din Muhammad Imran , Hussain Zaib , Bhatti Ijaz A. , Al-Kadhi Nada S. , Alamro Fowzia S. 
Published: July 2022

Abstract
The kinetics of polypropylene pyrolysis has been studied under isothermal and non-isothermal conditions using Arrhenius and Kissinger–Akahira–Sunose (KAS) equations. Under isothermal conditions, applying first order kinetic model, activation energy (Ea) and pre-exponential factor (A) were investigated and observed as 119.7 kJ mol−1 and 1.2 × 1010 min−1, while in case of non-isothermal kinetics using Kissinger–Akahira–Sunose method, the average Ea and A were found to be 91.23 kJ mol−1 and 2.3 × 107 min−1, respectively. A comparison among the isothermal and non-isothermal reactions was made on the basis of kinetics parameters. The results from both the methods showed trivial variation in kinetic parameters of the pyrolysis reaction which may be due to two major reasons. Firstly, the selection of the kinetic model applied and secondly the inconsistency due to various experimental conditions used which can be reduced at optimized conditions. As the disposal of plastic materials need reliable kinetics information to model their decomposition reactions, therefore, the kinetics data thus obtained from pyrolysis reaction of model polypropylene will help in the utilization of polypropylene waste as energy source on industrial scale.
Ultrasensitive Quantification of Multiple Estrogens in Songbird Blood and Microdissected Brain by LC-MS/MS
Authors: Jalabert Cecilia , Shock Maria A. , Ma Chunqi , Bootsma Taylor J. , Liu Megan Q. , Soma Kiran K. 
Published: July 2022

AbstractNeuroestrogens are synthesized within the brain and regulate social behavior, learning and memory, and cognition. In song sparrows,Melospiza melodia, 17β-estradiol (17β-E2) promotes aggressive behavior, including during the nonbreeding season when circulating steroid levels are low. Estrogens are challenging to measure because they are present at very low levels, and current techniques often lack the sensitivity required. Furthermore, current methods often focus on 17β-E2and disregard other estrogens. Here, we developed and validated a method to measure four estrogens [estrone (E1), 17β-E2, 17α-estradiol (17α-E2), estriol (E3)] simultaneously in microdissected songbird brain, with high specificity, sensitivity, accuracy, and precision. We used liquid chromatography tandem mass spectrometry (LC-MS/MS), and to improve sensitivity, we derivatized estrogens using 1,2-dimethylimidazole-5-sulfonyl-chloride (DMIS). The straightforward protocol improved sensitivity by 10-fold for some analytes. There is substantial regional variation in neuroestrogen levels in brain areas that regulate social behavior in male song sparrows. For example, the auditory area NCM, which has high aromatase levels, has the highest E1and 17β-E2levels. In contrast, estrogen levels in blood are very low. Estrogen levels in both brain and circulation are lower in the nonbreeding season than in the breeding season. This technique will be useful for estrogen measurement in songbirds and potentially other animal models.
Management of cranial diabetes insipidus: clinical outcomes and patient perception of care
Authors: Dilrukshi M D S A , Vickars Marcus , May Christine J H , Makaya Taffy , Ryan Fiona , Jafar-Mohammadi Bahram , Wass John A H , Pal Aparna , Garrahy Aoife 
Published: July 2022

Objective
There is growing recognition of morbidity and mortality that can occur in patients with cranial diabetes insipidus (CDI) during hospitalisation, due to prescribing errors and dysnatraemia, often related to confusion between CDI and diabetes mellitus among non-specialists. We aimed to investigate this.

Methods
Data for each hospitalisation in patients with CDI attending Oxford University Hospital (OUH) were collected retrospectively. The same cohort were invited to complete a questionnaire by telephone.

Results
One hundred and nine patients were included, median age was 42 (range: 6–80) years. Route of desmopressin was tablet, melt and nasal spray in 74%, 7% and 17% of patients, respectively, while two patients used a combination of tablet and nasal spray. There were 85 admissions to OUH by 38 patients between 2012 and 2021. Daily measurement of serum sodium was performed in 39% of admissions; hyponatraemia and hypernatraemia occurred in 44 and 15% of admissions, respectively. Endocrine consultation was sought in 63% of admissions post-2018. Forty-five of 78 patients (58%) self-reported ≥1 admission to any hospital since diagnosis. Of these, 53% felt their medical team did not have a good understanding of the management of CDI during hospital admission. Twenty-four per cent reported delay in administration of desmopressin, while 44% reported confusion between CDI and diabetes mellitus, often leading to unnecessary blood glucose monitoring.

Conclusion
Dysnatraemia is common in hospitalised patients with CDI. More than half of patients perceived their medical team’s understanding of CDI to be poor when admitted with intercurrent illness. A coordinated approach, including early consultation of specialists, frequent serum sodium monitoring, and education of hospital specialists is needed to address this.
De la ascendencia a la trascendencia del anthropos: 2001, una odisea prospectiva
Authors: Vargas Campos Ronulfo Alberto 
Published: July 2022

La obra de ficción Odisea 2001, en su expresión escrita y cinematográfica, es el motivo para analizar en este trabajo los 3 momentos de la historia humana -ascendencia, decadencia y trascendencia- que identifican al homo sapiens como un ser transitivo, un producto de la evolución autorrealizado pero en riesgo constante de sucumbir a su misma dinámica autopoiética. Según Clarke y Kubrick, el comienzo y ascenso de la especie sapiens radica en la evolución de la inteligencia desde una inducción extraterrestre, premisa que se desprende de la imaginación característica de la ciencia ficción.
El artículo hace una lectura analítica del objeto de estudio, y recurre a fuentes complementarias para contextualizar e interpretar las tesis de Clarke y Kubrick, e inferir conclusiones a partir de ellas. Se toma la perspectiva teórica del crítico de ciencia ficción Julián Díez, quien en su ensayo “Secesión” para la revista Hélice, aplica el concepto de prospección para denominar una categoría del género, que procura elaborar obras que operen como advertencia sobre futuros plausibles pero ingratos; la obra de ciencia ficción prospectiva “avisa sobre posibles desarrollos exacerbados de tendencias presentes en nuestra sociedad con el fin de denunciar su inconveniencia” (Díez 2008, p. 5). Desde esa perspectiva, este artículo determina que la evolución de la inteligencia humana es un medio paradójico: puede, o no, constituirse en medio de supervivencia, instrumento de dominación del ambiente, racionalidad objetiva que induce comportamientos e interacciones autodestructivas y finalmente lucidez autorreflexiva que ampara la posibilidad de evadir la extinción como destino.
Starting and stopping as energokinematic regimes of electric drives of indus-trial mechanisms
Authors: Rodkin D.I. , Khrebtova О.А. , Zachepa N.V. , Zachepa Yu.V. 
Published: July 2022

Purpose. To analyze the current technical terms that correspond to the physical processes in the electric drive system during atypical dynamic modes. Review possible modes in the kinematic parts of the electric drive during dynamic modes that may affect the nature of the transients. To form a definition of technical terms that characterize the real energy-kinematic regimes when moving and starting the electric drive of industrial mechanisms, which were not previously considered as insignificant or as non-existent.
Methodology. In order to solve the set tasks, the analysis of the technical terms defined by the technical literature, GOST, DSTU, etc. was carried out. To formulate new terminology for physical processes of atypical modes, the analysis of physical and energy processes occurring in the electrical and kinematic parts of the electric drive under such dynamic modes is performed..
Findings. Possible cases of atypical modes of operation of kinematic circuits and energy channels of energy conversion during the start-up of electric drives of technological mechanisms under load, for the characteristics of which there is no technical terminology, are identified. Based on the results of the analysis of energy-kinematic regimes, technical terminology is proposed, which fully covers and characterizes the considered atypical processes that take place during the moving and start-up of technological mechanisms.
Originality. For the first time, technical terminology has been proposed that characterizes the energy-kinematic modes of electric drives of technological mechanisms during start-up.
Practical value. For the first time, the use of technical terms is proposed for a clear and visual representation of energy kinematic modes that occur during the moving and start-up under load of different types of technological mechanisms.
Students’ Perceptions on Zoom Digital Media in Learning Speaking at SMP IT Fathona Palembang
Authors: Ismadella Rinda 
Published: July 2022

The aim of this study was to find out how students perceived the use of Zoom application in learning speaking. This study used qualitative study as its method. Five eighth-grade students from SMP IT Fathona Palembang took part in this study. They were chosen purposively. The data from the interview was evaluated using thematic analysis. There were 4 categories of students’ perception on Zoom digital media in learning speaking: 1) helpful in learning speaking; 2) costly application; 3) difficulty in internet connection; and 4) aspects of learning speaking. Finally, the findings revealed that the majority of students enjoy and are more engaged in learning speaking taught by using Zoom application.
A QUALITATIVE STUDY: HOSPITAL PATIENT COMPLAINT MANAGEMENT
Authors: Hastuti Siti Kurnia Widi , Baginda Nikita Cahyani , Anda Selly Apri 
Published: July 2022

Background: Complaint management is vital for hospitals as patient complaints can be used to advance the quality of health services provided.
Aims: This study analyzed patient complaint management at an X government hospital in Yogyakarta.
Methods: The research used a descriptive-qualitative method and phenomenology, which was carried out through in-depth interviews, observation, and document review. It involved the head of the legal and public relations department, the head of the public relations sub-division, two staff of the legal and public relations department, two officers to outpatient and inpatient units, and two patients. This study used purposive sampling to select the samples. Data analysis referred to was from the concept of Miles and Huberman, which consists of data reduction, display, and verification. The accuracy of all data was checked using a triangulation method.
Results: The hospital followed the patient complaint management procedures. Providing complaint reporting platforms is required to lodge patient complaints to the hospital. Moreover, the suggestion box should be managed properly, and thus the complaints on the box can be managed promptly.
Conclusion: Overall, patient complaint management at the hospital has been carried out well and followed the standard operating procedures (SOP).
Problematika yang Muncul pada Program Tahfidz Al-Qur’an dengan Model Pembelajaran Tutorial Sebaya.
Authors: Muzakki Muhammad , Gani Abdul , Zulkifli Zulkifli 
Published: July 2022

Tujuan penelitian ini adalah untuk mengetahui problematika yang muncul pada program Tahfidz Al-Qur’an dengan model pembelajaran Tutorial Sebaya. Metode yang digunakan adalah matode diskriptif kulitatif sumber data pada penelitian ini berupa kata-kata, gambar dan bukan angka. Metode penelitian menggunakan wawancara, catatan lapangan dan dokumentasi.Teknik analisis data yang digunakan dalam penelitian ini adalah analisis data kualitatif, mengikuti konsep yang diberikan Miles and Huberman dan Spradley. Hasil penelitian menunjukan bahwa problematika program Tahfidz Al-Quran model Tutor Sebaya adalah 1) Metode 2) Perekrutan calon Tutor Sebaya 3) Materi 4) Waktu bimbingan Tutor Sebaya dan Tahfidz Al-Qur’an di kelas; para Tutor Sebaya dan siswa terkendala dengan waktu yang telah ditentukan dengan alasan masih repot membantu orang tua serta waktu bimbingan Tutor Sebaya dan Tahfidz Al-Qur’an terlalu singkat. 5) Teknis setor hafalan; Minimnya kontrol dan pengawasan para guru pembimbing saat Tahfidz Al-Qur’an Tutorial Sebaya berlangsung di dalam kelas yang kemudian berdampak banyak siswa yang tidak menyetorkan hafalannya, waktu setor hafalan terbentur dengan waktu mengajar guru di kelas.
Imaging Markers of Neurologic Damage in COVID-19: A Systematic
Review
Authors: Araújo Sara Tavares , Araújo Clara Tavares , Silva e Castro Rafael , de Oliveira Brügger Lara Machado , Souza e Silva Nathália Gualberto , de Miranda Debora Marques , Simões e Silva Ana Cristina 
Published: July 2022

Background and Objective:
Severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection commonly leads to neurologic manifestations. In the present
review, we aimed to investigate potential neuroimaging markers of early diagnosis and
prognosis of neurologic manifestations in COVID-19.

Methods:
Our study was registered in the Prospective Register of Systematic Reviews
(PROSPERO) under the protocol CDR42021265443. Based on the Preferred Reporting
Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we selected 51
studies for whole-manuscript analysis.

Results:
Magnetic resonance imaging (MRI) was the most common imaging method.
The pattern, sites of lesion, signs, and symptoms of neurologic injury varied. Such manifestations
possibly resulted from a direct viral infection or, most likely, from indirect
mechanisms including coagulation disturbances, hypoxemia, and immunological responses.

Conclusion:
The heterogeneity of the studies precludes any generalization of the findings.
Brain MRI is the most informative imaging exam. Population studies, including the
entire spectrum of COVID-19 are missing. There is still a need for future population
studies evaluating neurologic manifestations of all COVID-19 severities acutely and
chronically.
Evaluation of Image Classification for Quantifying Mitochondrial Morphology
Using Deep Learning
Authors: Sugimori Hiroyuki , Tsutsumi Kaori , Tokunaga Keima , Saito Shun , Sasase Tatsuya 
Published: July 2022

Background:
Mitochondrial morphology reversibly changes between fission and fusion.
As these changes (mitochondrial dynamics) reflect the cellular condition, they are one of the simplest
indicators of cell state and predictors of cell fate. However, it is currently difficult to classify
them using a simple and objective method.

Objective:
The present study aimed to evaluate mitochondrial morphology using Deep Learning
(DL) technique.

Methods:
Mitochondrial images stained by MitoTracker were acquired from HeLa and MC3T3-E1
cells using fluorescent microscopy and visually classified into four groups based on fission or fusion.
The intra- and inter-rater reliabilities for visual classification were excellent [(ICC(1,3), 0.961
for rater 1; and 0.981 for rater 2) and ICC(1,3), respectively]. The images were divided into test and
train images, and a 50-layer ResNet CNN architecture (ResNet-50) using MATLAB software was
used to train the images. The datasets were trained five times based on five-fold cross-validation.

Result:
The mean of the overall accuracy for classifying mitochondrial morphology was 0.73±0.10
in HeLa. For the classification of mixed images containing two types of cell lines, the overall accuracy
using mixed images of both cell lines for training was higher (0.74±0.01) than that using different
cell lines for training.

Conclusion:
We developed a classifier to categorize mitochondrial morphology using DL.
Identification of Candidate Immune System MicroRNAs Differentially
Found in Colostrum and Milk Exosomes
Authors: Verma Poonam , Mohanty Niharika , Pruseth Babita , Sahoo Sonali , Katiyar Amit , Singh Harpreet , Jena Saubhagya Kumar , Das Rashmi Ranjan , Som Tapas Kumar , Sahoo Sanjeeb Kumar , Nanda Pranati , Ghosh Amit 
Published: July 2022

Background:
The fetus grows in a sterile womb environment. After birth, the newborn
immune system has two immediate hurdles to clear. First immediate suppression of the womb compatible
immune system and turn on the immune system of the newborn that can counter the antigenic
world. The underlying mechanism of immune fluctuation by milk microRNAs (miRNAs) can be
crucial for the treatment of critical or premature newborn.

Methods:
We collected fourteen samples of each colostrum and mature milk from lactating mothers,
four samples of each were used for microarray analysis, and the other ten were used for miRNA
expression profiling by real-time PCR.

Results:
From the microarray, 154 differentially expressed miRNAs were identified, whereas 49
miRNAs were revealed as immune-related miRNAs based on a literature study. Among the 49
miRNAs, 33 were already shown as strongly validated immune-related miRNAs (validated by
qPCR, Western Blot, and Luciferase assay) and were considered for further analysis. Twenty-two
miRNA expressions were analysed by real-time PCR as their Ct values were within considerable
limits. Twelve numbers of miRNAs were significantly downregulated in mature milk compared to
colostrum, which were again subjected to bioinformatics analysis to predict the biological mechanisms
behind the differentially expressed miRNAs.

Conclusion:
This study shed light on the human milk exosome miRNA expression dynamics during
lactation and their possible role in the gradual skewing of the newborns' immune system. The information
is crucial for the development and onset of sepsis in premature newborns in the NICU.
Psychometric Properties of the COVID-19 Pandemic Fatigue Scale: Cross-sectional Online Survey Study
Authors: Rodriguez-Blazquez Carmen , Romay-Barja Maria , Falcon Maria , Ayala Alba , Forjaz Maria João 
Published: July 2022

Background
Pandemic fatigue is defined as feelings of demotivation to follow preventive measures against COVID-19, together with decreased trust in government and frequency of information-seeking behaviors.

Objective
This study aims to analyze the psychometric properties of the COVID-19–specific pandemic fatigue scale according to classical test theory (CTT) and Rasch model approaches in the general Spanish population.

Methods
This was a cross-sectional study in a representative sample of 1018 adults who completed an online survey in November 2020 in the framework of the COVID-19 Snapshot Monitoring (COSMO)-Spain project. The assessments included the 6-item COVID-19 Pandemic Fatigue Scale (CPFS) and other COVID-19–related variables: COVID-19 infection, adherence to preventive behaviors, information-seeking behavior, self-efficacy, worry, and cognitive and affective risk perception. Data quality, acceptability, reliability, and validity were analyzed according to CTT, and the fit to the Rasch model, unidimensionality, appropriateness of the response scale, item local independency, reliability (person-separation index [PSI]), and item-person distribution were also calculated.

Results
The mean CPFS score was 17.06 (SD 5.04, range 6-30), with higher scores for women, younger participants, participants who never seek information on COVID-19, those who think they would contract a mild disease in case of infection, those with higher level of worry about coronavirus/COVID-19, and those who felt depressed or felt the coronavirus/COVID-19 is spreading slowly (all P<.01). The Cronbach alpha for the CPFS was 0.74. In the confirmatory factor analysis, one factor was identified (root mean square error of approximation [RMSEA]=.02; comparative fit index [CFI]=.99; χ25=8.06, P=.15). The CPFS showed good fit to the Rasch model (χ 224=42.025, P=.01, PSI=.642), unidimensionality (binomial 95% CI –.005 to .045), and item local independency.

Conclusions
Our results suggest that the CPFS has moderate reliability and internal consistency and it is composed of a single dimension. It is a useful tool to ascertain the level of pandemic fatigue in the general population, which may help to guide the communication and information strategies to face the COVID-19 pandemic.
Pandemic-Triggered Adoption of Telehealth in Underserved Communities: Descriptive Study of Pre- and Postshutdown Trends
Authors: Xu Pei , Hudnall Matthew , Zhao Sidi , Raja Uzma , Parton Jason , Lewis Dwight 
Published: July 2022

Background
The adoption of telehealth services has been a challenge in rural communities. The reasons for the slow adoption of such technology-driven services have been attributed to social norms, health care policies, and a lack of infrastructure to support the delivery of services. However, the COVID-19 pandemic–related shutdown of in-person health care services resulted in the usage of telehealth services as a necessity rather than a choice. The pandemic also fast-tracked some needed legislation to allow medical cost reimbursement for remote examination and health care services. As services return to normalcy, it is important to examine whether the usage of telehealth services during the period of a shutdown has changed any of the trends in the acceptance of telehealth as a reliable alternative to traditional in-person health care services.

Objective
Our aim was to explore whether the temporary shift to telehealth services has changed the attitudes toward the usage of technology-enabled health services in rural communities.

Methods
We examined the Medicaid reimbursement data for the state of Alabama from March 2019 through June 2021. Selecting the telehealth service codes, we explored the adoption rates in 3 phases of the COVID-19 shutdown: prepandemic, pandemic before the rollout of mass vaccination, and pandemic after the rollout of mass vaccination.

Results
The trend in telemedicine claims had an opposite pattern to that in nontelemedicine claims across the 3 periods. The distribution of various characteristics of patients who used telemedicine (age group, gender, race, level of rurality, and service provider type) was different across the 3 periods. Claims related to behavior and mental health had the highest rates of telemedicine usage after the onset of the pandemic. The rate of telemedicine usage remained at a high level after the rollout of mass vaccination.

Conclusions
The current trends indicate that adoption of telehealth services is likely to increase postpandemic and that the consumers (patients), service providers, health care establishments, insurance companies, and state and local policies have changed their attitudes toward telehealth. An increase in the use of telehealth could help local and federal governments address the shortage of health care facilities and service providers in underserved communities, and patients can get the much-needed care in a timely and effective manner.