bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hubungan Derajat Aktivitas Penyakit Dengan Fibromialgia Pada Pasien Systemic Lupus Erythematosus (SLE) di Komunitas Odapus Lampung
Authors: Gariana Saniyyah Army , Ladyani Festy , Esfandiari Firhat , Kriswiastiny Rina 
Published: May 2022

ABSTRACT Systemic Lupus Erythematosus (SLE) is a participatory systemic autoimmune condition involving many organ systems in the body and high production of autoantibodies. Objective to see the relationship between the degree of disease activity and fibromyalgia in systemic lupus eriythematosus patients in the ODAPUS Lampung community in 2020. Cross-sectional analytic. Sampling was done using total sampling. Respondents of this study were all Lupus patients in the ODAPUS Community in Lampung, as many as 40 people. Showed that from 40 patient respondents, 5 respondents (12.5%) had the degree of mild disease activity, 35 respondents (87.5%) had no diagnosis. fibromyalgia 14 Respondents (35.0%), diagnosed with fibromyalgia 26 respondents (65.0%) Chi Square analysis results obtained p-value = 0.000 (p ≤ 0.05), which is a relationship between the degree of disease activity and fibromyalgia in systemic lupus patients eriythematosus in the ODAPUS community in Lampung. The existence of a relationship between the degree of disease activity and fibromyalgia in systemic lupus eriythematosus (SLE) patients in the Lampung ODAPUS community in 2020 with (p <0.05) Key words: Disease Degree, Fibromyalgia, SLE ABSTRAK Systemic Lupus Erythematosus (SLE) merupakan kondisi autoimun sistemik ditandai dengan melibatkan banyak sistem organ didalam tubuh serta didapatkan produksi kadar yang tinggi pada autoantibodi. Tujuan penelitian ini untuk mengetahui hubungan antara derajat aktivitas penyakit dengan fibromialgia pada pasien systemic lupus eriythematosus di komunitas ODAPUS lampung. Bersifat analitik secara cross sectional. Pengambilan sampel dilakukan dengan menggunakan Total sampling. Responden penelitian ini adalah seluruh pasien Lupus di Komunitas ODAPUS Lampung sebanyak 40 orang. Hasil penelitian menunjukkan dari 40 responden didapatkan pasien derajat aktivitas penyakit ringan 5 responden (12,5%), derajat aktivitas penyakit berat 35 responden (87,5%), tidak terdiagnosa fibromialgia 14 Responden (35,0%), terdiagnosis fibromialgia 26 responden (65,0%) Hasil analisis uji Chi Square didapatkan p-value = 0,000 (p ≤ 0,05) yaitu Terdapat hubungan antara derajat aktivitas penyakit dengan fibromialgia pada pasien systemic lupus eriythematosus di komunitas ODAPUS lampung. Terdapat hubungan antara derajat aktivitas penyakit dengan fibromialgia pada pasien systemic lupus eriythematosus (SLE) di komunitas ODAPUS lampung tahun 2020 dengan (p< 0,05) Kata kunci : Derajat penyakit, Fibromialgia, SLE
Hubungan Komunikasi Terapeutik Perawat Dengan Kepuasan Pasien Di Ruang Rawat Inap Melur Dewasa RSUD. Ferdinand L. Tobing Kota Sibolga
Authors: Simamora Natalia Dermawan , Naziyah Naziyah , Usman Andi Mayasari 
Published: May 2022

ABSTRACT Nursing is a profession that is focused on caring for individual families and communities in restoring their health. This study aims to determine the relationship of nurse therapeutic communication with patient satisfaction in the adult Melur inpatient room at Ferdinand L Tobing Sibolga Hospital. The research design used is descriptive correlative with a cross-sectional approach. The sample in this study amounted to 88 people using the solving formula. The sampling technique used was random sampling. The data were analyzed using the Spartan rank test to determine the relationship between variables. The results of this study indicate that there is a relationship between nurse therapeutic communication and patient satisfaction (p = 0.003). From the research results, the majority of therapeutic communication is still lacking, patient satisfaction is still low and there is a relationship between nurse therapeutic communication and patient satisfaction. Keywords: Patient Satisfaction, Therapeutic Communication, Nursing ABSTRAK Perawat merupakan profesi yang difokuskan pada perawatan individu keluarga dan masyarakat dalam memulihkan kesehatannya. Penelitian ini bertujuan untuk mengetahui hubungan komunikasi terapeutik perawat dengan kepuasan pasien di ruang rawat inap Melur dewasa RSUD Ferdinand L Tobing Sibolga. Desain Penelitian ini menggunakan deskriptif korelatif dengan pendekatan cross sectional . Sampel pada penelitian ini berjumlah 88 orang menggunakan rumus slovin. Tehnik pengambilan sampel menggunakan random sampling. Data dianalisis menggunakan uji rank sparman untuk mengetahui hubungan antar variable. Hasil penelitian ini menunjukan adanya hubungan komunikasi terapeutik perawat dengan kepuasan pasien (p= 0,003 ). Dari hasil penelitian mayoritas komunikasi terapeutiknya masih kurang, dan kepuasan pasien masih rendah serta terdapat hubungan antara komunikasi terapeutik perawat dengan kepuasan pasien. Kata kunci: Kepuasan Pasien, Komunikasi Terapeutik, Perawat
Kualitas Fisik dan Kimia Air Bersih di Pasar Beringharjo Yogyakarta
Authors: Amyati Amyati 
Published: May 2022

Banyaknya pengunjung di Pasar Beringharjo membuat kami tertarik untuk mengetahui kualitas air yang tersedia di sana, dengan mengidentifikasi dari parameter fisik dan kimia. Fasilitas sanitasi masih belum sepenuhnya baik seperti toilet/kamar mandi yang bau, jumlah tempat cuci tangan yang airnya habis, tempat pembuangan sampah maupun tempat penampungan sampah yang belum tertata dengan baik sehingga menimbulkan pemandangan yang tidak nyaman untuk dilihat dan menimbulkan pencemaran udara. Penelitian ini bertujuan untuk menguji parameter fisika yaitu TDS, Kekeruhan,Rasa, Bau, Suhu dan kimia meliputi pH, Besi, Fluorida,Kesadahan, Mangan, Nitrat, Nitrit, Sianida, Deterjen yang terdapat pada air bersih yang ada di Pasar Beringharjo, Yogyakarta. Metode penelitian ini adalah deskriptif. Populasi dalam penelitian ini 55 lokasi air di Pasar Beringharjo. Teknik pengambilan sampel menggunakan purposif sampling. Sampel dalam penelitian ini adalah 10 sampel air bersih pada fasilitas sanitasi di Pasar Beringharjo. Pemeriksaan sampel dilakukan di Laboratorium BBTKL PP, Dinas Kesehatan Yogyakarta. Hasil analisis laboratorium terkait 10 sampel air bersih dengan parameter fisika dan kimia terdapat 7 sampel yang belum memenuhi syarat-syarat air bersih untuk keperluan higiene sanitasi terbatas sedangkan 3 sampel air bersih sudah memenuhi syarat sesuai dengan Permenkes RI No.32 tahun 2017. Parameter yang paling banyak belum memenuhi syarat yaitu Besi (Fe), Nitrat (NO3-N) dan Bau.
Analisis Faktor Bio-sosial Pertumbuhan dan Perkembangan Anak Tunagrahita
Authors: Syarfaini Syarfaini , Bujawati Emmi , Aeni Syahratul 
Published: May 2022

Proses tumbuh kembang anak dapat menentukan kualitas anak, termasuk diantaranya adalah anak dengan retardasi mental (tunagrahita). Penelitian ini bertujuan untuk melihat hubungan status berat badan lahir bayi dan pola pengasuhan orang tua terhadap tumbuhmkembang anak tunagrahita. Penelitian ini merupakan penelitian kuantitatif dengan pendekatan analitik observasional dan desain studi cross sectional. Populasi dalam penelitian ini adalah seluruh siswa tunagrahita di UPT SLBNm1 Marosm dan jumlah sampel dalam penelitian ini sama dengan jumlah populasi karena menggunakan teknik exhaustive sampling yaitu sebanyak 31 orang. Hasil penelitian menggunakan uji chi-square menunjukkan tidak ada hubungan antara status berat lahir bayi dengan pertumbuhan (Pv=1,000) dan perkembangan kemampuan dasar (Pv=0,624). Begitu pun dengan tipe pola asuh tidak berhubungan dengan dengan pertumbuhan (Pv=0,771) dan perkembangan kemampuan anak retardasinmental (Pv=0,771) di UPT SLBN 1 Kab. Maros. Penelitian ini merekomendasikan pencegahan dan penanganan serius bayi berat lahir rendah dan memberikan sebuah pelatihan pola asuh kepada orang tua agar dapat memaksimalkan kemandirian anak dengan keterbatasan mental dengan hal-hal yang menyenangkan dalam bentuk bermain, menonton, bernyanyi, menari, dan sebagainya.
Feeding behaviour of pit building of antlion Myrmeleon pseudohyalinus, Holzel 1972 (Neuroptera: Myrmeleontidae) in different mediums, instars and hunger levels
Authors: Anila K. , Kakkassery Francy K , Jose Joyce 
Published: May 2022

Feeding behaviour of Myrmeleon pseudohyalinus (Holzel, 1972) larvae was studied in sand and soil media for second and third instars, and at two hunger levels (fed/starved) in laboratory conditions. Common ant Anoplolepis gracilipes (Smith, 1857) was used as prey in all the experiments. From the eight experiments, feeding time, prey escape and capture success were analysed. The predatory efficiency studied indicated that the capture success was high in second instar larvae irrespective of hunger level and medium. The relationships between selected behaviour, instar, medium and condition were studied and also the relationship between selected behaviour, instar, medium, condition and time period were analysed. From the Canonical Correspondence Analysis (CCA), it is clear that the prey beating, emergence and submergence behaviours were influenced by the larval instar (second and third) and quiescence, pit clearing and jaw set behaviour patterns were influenced by their condition (fed or starved). CCA also shows an influence of time period in the feeding behaviour pattern of antlion larvae.
Larvicidal potential of rhizome extracts of Elettaria cardamomum (L.) Maton against filarial vector, Culex quinquefasciatus Say, 1823 (Diptera: Culicidae)
Authors: Mallick Subrata 
Published: May 2022

Investigation on the larvicidal potential of Elettaria cardamomum (L.) Maton rhizome extracts against filarial vector, Culex quinquefasciatus Say, was undertaken with crude concentrations 0.1-0.5 per cent and 40, 50, and 60 ppm of each of petroleum ether, hexane and ethyl acetate rhizome extracts revealed that first instar larvae were most susceptible to crude rhizome extract with 100 per cent mortality at 0.5% after 24 hrs of exposure. Among three solvent extracts, ethyl acetate extract showed maximum mortality (96.66±3.33%) at 60 ppm after 72 hrs of exposure. LC50 values of larvicidal bioassays by crude rhizome extract were 0.1002, 0.0794, 0.1275 and 0.6334 ppm for 1st, 2nd, 3rd and 4th instars larvae after 72 hrs of exposure, respectively and LC50 values for larvicidal bioassays by petroleum ether, hexane, and ethyl acetate rhizome extracts were 48.3629, 40.9613 and 37.0282 ppm against 3rd instar larvae after 72 hrs of exposure, respectively. Preliminary phytochemical analyses of the rhizome extracts showed presence of secondary metabolites. Non target organisms, tadpoles of frog and 4th instar larvae of Chironomus circumdatus, were not affected by the crude as well as ethyl acetate rhizome extracts. Larvicidal efficacy of the rhizome extracts of E. Cardamomum against Cx. quinquefasciatus mosquito species has been reported first time.
Gebelikte Doğum Korkusu ve Etkileyen Faktörler
Authors: BİLGE Çiğdem , DÖNMEZ Sevgül , OLGAÇ Zeliha , PİRİNÇÇİ Fatih 
Published: May 2022

Amaç: Araştırma gebe kadınların doğum korkularını ve bu korkuları etkileyen faktörlerini belirlemek amacıyla tanımlayıcı ve ilişki arayıcı tasarımda yapılmıştır.
Gereç ve Yöntemler: Çalışma, Muğla Sıtkı Koçman Üniversitesi Eğitim ve Araştırma Hastanesi’nin kadın hastalıkları ve doğum polikliniğinde gerçekleştirilmiştir. Çalışmaya 203 gebe dahil edilmiştir. Verilerin toplanmasında gebelerin sosyodemografik özelliklerini belirleyen tanılama formu ve doğum korkusunu değerlendiren Wijma Doğum Beklentisi/ Deneyimi Ölçeği- A Versiyonu kullanılmıştır. Veriler SPSS 20,0 programında tanımlayıcı istatistikler, Student t-testi, Ki-Kare ve Mann Whitney U analizleri ile değerlendirilmiştir. Bulgular: Katılımcıların yaş ortalaması 28,36±4,85 olup, %42,8'inin üniversite mezunu ve %64,9'unun gelir düzeyi gider düzeyine eşit olduğu saptanmıştır. Araştırmada gebelerin doğum korkusu puan ortalamasının 52,48±15,70 olduğu belirlenmiştir. Gebelerin bulundukları trimester dönemleri, gebelikte eşinden destek alma, daha önce gebelik geçirme durumları ile doğum korkusu puan ortalamaları arasında anlamlı bir ilişki bulunmuştur. Bununla birlikte canlı doğum sayısı, önceki doğum şekli ve doğum öncesi gebelik ve doğum ile ilgili bilgi alma durumları arasında Wijma Doğum Beklentisi/ Deneyimi Ölçeği puan ortalamaları arasındaki ilişki bulunamamıştır.
Sonuç: Araştırmada, gebelerin doğum korkusu düzeyleri yüksek bulunmuştur. Yaşı daha genç olan, eğitim seviyesi yüksek, geliri giderinden az olduğunu ifade eden, gebelerde de doğum korkusu yüksek, ilk gebeliği olan, eşinden fiziksel ya da duygusal destek alamadığını ifade eden ve ikinci trimesterde olan kadınların doğum korkusunun daha yüksek olduğu belirlenmiştir. Ayrıca çalışmada sağlık profesyonelleri tarafından verilen eğitim ile kadınların doğum korkusunun azaldığı saptanmıştır.
Tekrarlayan Gebelik Kayıpları Nedeniyle Çalışılan 306 Çiftin Kromozom Analizi ve Trombofili Parametrelerinin Değerlendirilmesi: Tek Merkez Deneyimi
Authors: DOĞAN Mustafa , GEZDİRİCİ Alper , YAVAŞ Cüneyd , ERÖZ Recep 
Published: May 2022

Amaç: Bu çalışmanın amacı, hastanemize tekrarlayan gebelik kaybı nedeniyle başvuran çiftlere uygun genetik danışmanlık verebilmek için hem majör kromozom anomalilerinin hem de trombofili parametrelerinin etiyolojideki rolünü araştırmaktır.
Gereç ve Yöntemler: Çalışmamıza tekrarlayan gebelik kaybı nedeniyle Başakşehir Çam ve Sakura Şehir Hastanesi Genetik Hastalıklar Değerlendirme Merkezi'ne başvuran toplam 306 çift dâhil edildi. Tüm hastalarda kromozom analizleri ve 306 bayanda trombofili parametrelerinin analizleri gerçekleştirildi.
Bulgular: Çalışmamızda toplam 306 çiftin 13’ünde (%4,25) polimorfizm dışında kalan kromozomal anomaliler tespit edildi. 4 hastada robertsonian translokasyon, 3 hastada resiprokal traslokasyon, 4 hastada mozaik kromozom kuruluşu, 1 hastada yapısal kromozal dengesizlik (derivatif kromozom) ve 1 hastada sayısal kromozal anomali varlığı tespit edilmiştir. Geriye kalan 293 çiftin kromozom analizi normaldi. Çalışmamızda trombofili parametreleri analiz edilen 306 bayan olgunun yaklaşık %10’unda Faktör V Leiden varyantı saptanırken, Faktör II G20210A varyantı ise yaklaşık %3,5 oranında saptanmıştır. 3 hastada (%1) Faktör V Leiden varyantı homozigot, 27 hastada ise Faktör V Leiden varyantı (%8,8) heterozigot olarak saptanmıştır. 10 hastanın (%3,3) Faktör II G20210A varyantını heterozigot olarak taşıdıkları saptanmıştır. Faktör II G20210A varyantını homozigot olarak taşıtan bir hasta çalışmamızda saptanmamıştır.
Sonuç: Mevcut bilgiler ve geçmişteki literatür çalışmaları eşliğinde tekrarlayan gebelik kaybı nedeniyle değerlendirilen çiftlerde etiyolojiyi aydınlatmak için kromozom analizi ve trombofili parametrelerinin değerlendirilmesini ve bu parametrelerde ilişkili olduğu düşünülen bir neden saptandığında tedavi imkanları bulunduğundan dolayı özellikle yardımcı üreme tekniklerinden önce bu analizlerin yapılmasını önermekteyiz.
Clinical Features and Evolution of Blepharospasm: A Multicenter International Cohort and Systematic Literature Review
Authors: Scorr Laura M. , Cho Hyun Joo , Kilic-Berkmen Gamze , McKay J. Lucas , Hallett Mark , Klein Christine , Baumer Tobias , Berman Brian D. , Feuerstein Jeanne S. , Perlmutter Joel S. , Berardelli Alfredo , Ferrazzano Gina , Wagle-Shukla Aparna , Malaty Irene A. , Jankovic Joseph , Bellows Steven T. , Barbano Richard L. , Vidailhet Marie , Roze Emmanuel , Bonnet Cecilia , Mahajan Abhimanyu , LeDoux Mark S. , Fung Victor S.C. , Chang Florence C.F. , Defazio Giovanni , Ercoli Tomaso , Factor Stewart , Wojno Ted , Jinnah H. A. 
Published: May 2022

Objective: Blepharospasm is a type of dystonia where the diagnosis is often delayed because its varied clinical manifestations are not well recognized. The purpose of this study was to provide a comprehensive picture of its clinical features including presenting features, motor features, and non-motor features.Methods: This was a two-part study. The first part involved a systematic literature review that summarized clinical features for 10,324 cases taken from 41 prior reports. The second part involved a summary of clinical features for 884 cases enrolled in a large multicenter cohort collected by the Dystonia Coalition investigators, along with an analysis of the factors that contribute to the spread of dystonia beyond the periocular region.Results: For cases in the literature and the Dystonia Coalition, blepharospasm emerged in the 50s and was more frequent in women. Many presented with non-specific motor symptoms such as increased blinking (51.9%) or non-motor sensory features such as eye soreness or pain (38.7%), photophobia (35.5%), or dry eyes (10.7%). Non-motor psychiatric features were also common including anxiety disorders (34–40%) and depression (21–24%). Among cases presenting with blepharospasm in the Dystonia Coalition cohort, 61% experienced spread of dystonia to other regions, most commonly the oromandibular region and neck. Features associated with spread included severity of blepharospasm, family history of dystonia, depression, and anxiety.Conclusions: This study provides a comprehensive summary of motor and non-motor features of blepharospasm, along with novel insights into factors that may be responsible for its poor diagnostic recognition and natural history.
Analysis of Negative Results of Metagenomics Next-Generation Sequencing in Clinical Practice
Authors: Qian Mengjia , Zhu Bijun , Zhan Yanxia , Wang Lingyan , Shen Qi , Zhang Miaomiao , Yue Lei , Wu Duojiao , Chen Hao , Wang Xiangdong , Cheng Yunfeng 
Published: May 2022

BackgroundMetagenomics next-generation sequencing (mNGS) has been increasingly used in the clinic, which provides a powerful tool for the etiological diagnosis of infectious diseases. Precise treatment can be carried out according to the positive mNGS results. However, the role of negative results of mNGS remains poorly defined in clinical practice.MethodsThe results of 1,021 samples from patients who received the mNGS test at Zhongshan Hospital, Fudan University, between January 2019 and December 2019 were analyzed.ResultsThere were 308 samples (30.17%) of negative results included in the current study. The top 2 types of negative samples were blood (130/308) and tissue (63/308), which also accounted for the highest negative proportion in diseases. Sputum and bronchoalveolar lavage fluid (BALF) were more likely to have positive results. In false-negative results (defined as negative in mNGS test but reported positive in other sample types or assays), 118 samples were found when compared to regular microbiological assays. The negative predictive value (NPV) of mNGS was 95.79% [95%CI, 93.8%–97.8%] as compared to culture and smear. Mycobacterium, Aspergillus, and Mycoplasma ranked as the top 3 microorganisms on the undetected pathogen list.ConclusionsThe present data indicate that when the mNGS test is negative, the negative prediction accuracy rate of the original specimen is significant. However, other laboratory assays results and clinical presentations should always be carefully considered prior to drawing a diagnosis.
Assessment of New Onset Arrhythmias After Transcatheter Aortic Valve Implantation Using an Implantable Cardiac Monitor
Authors: Nozica Nikolas , Siontis George C. M. , Elchinova Elena Georgieva , Goulouti Eleni , Asami Masahiko , Bartkowiak Joanna , Baldinger Samuel , Servatius Helge , Seiler Jens , Tanner Hildegard , Noti Fabian , Haeberlin Andreas , Branca Mattia , Lanz Jonas , Stortecky Stefan , Pilgrim Thomas , Windecker Stephan , Reichlin Tobias , Praz Fabien , Roten Laurent 
Published: May 2022

BackgroundTranscatheter aortic valve implantation (TAVI) is associated with new onset brady- and tachyarrhythmias which may impact clinical outcome.AimsTo investigate the true incidence of new onset arrhythmias within 12 months after TAVI using an implantable cardiac monitor (ICM).MethodsOne hundred patients undergoing TAVI received an ICM within 3 months before or up to 5 days after TAVI. Patients were followed-up for 12 months after discharge from TAVI for the occurrence of atrial fibrillation (AF), bradycardia (≤30 bpm), advanced atrioventricular (AV) block, sustained ventricular and supraventricular tachycardia.ResultsA previously undiagnosed arrhythmia was observed in 31 patients (31%) and comprised AF in 19 patients (19%), advanced AV block in 3 patients (3%), and sustained supraventricular and ventricular tachycardia in 10 (10%) and 2 patients (2%), respectively. Three patients had a clinical diagnosis of sick-sinus-syndrome. A permanent pacemaker (PPM) was implanted in six patients (6%). The prevalence of pre-existing AF was 28%, and 47% of the patients had AF at the end of the study period. AF burden was significantly higher in patients with pre-existing [26.7% (IQR 0.3%; 100%)] compared to patients with new-onset AF [0.0% (IQR 0.0%; 0.06%); p = 0.001]. Three patients died after TAVI without evidence of an arrhythmic cause according to the available ICM recordings.ConclusionsRhythm monitoring for 12 months after TAVI revealed new arrhythmias, mainly AF, in almost one third of patients. Atrial fibrillation burden was higher in patients with prevalent compared to incident AF. Selected patients may benefit from short-term remote monitoring.Trial Registrationhttps://clinicaltrials.gov/: NCT02559011.
The Effect of SMS Reminders on Adherence in a Self-Guided Internet-Delivered Intervention for Adults With ADHD
Authors: Nordby Emilie S. , Gjestad Rolf , Kenter Robin M. F. , Guribye Frode , Mukhiya Suresh K. , Lundervold Astri J. , Nordgreen Tine 
Published: May 2022

BackgroundSelf-guided Internet-delivered interventions may serve as an accessible and flexible non-pharmacological treatment supplement for adults with ADHD. However, these interventions are challenged by low adherence.ObjectiveTo examine whether weekly SMS reminders improve adherence to a self-guided Internet-delivered intervention for adults with ADHD.MethodThe study used a multiple randomized trial design where the participants who had not completed their weekly module within 2 days were randomized to either receive or not receive an SMS reminder. The primary outcome was adherence, defined as module completion, logins, time spent on intervention, and self-reported practice of coping strategies.ResultsA total of 109 adults with a self-reported ADHD diagnosis were included in the study. The results showed that SMS reminders were associated with an increased likelihood of login within 48 h during the second module of the intervention, but not for the remaining modules. Moreover, receiving an SMS reminder was associated spending more time on the modules and faster login time in module three and five, specifically. However, the overall results did not show an effect of SMS reminders on module completion, number of logins or practice of coping strategies.ConclusionThe results showed that SMS reminders do not improve number of logins, module completion rates or practice of coping strategies, but they may lead to faster login time and more time spent on the modules. To utilize the potential of self-guided Internet-delivered intervention in making non-pharmacological accessible for adults with ADHD, new methods to facilitate meaningful engagement should be developed and tested.Trial RegistrationClinicalTrials.gov NCT04511169.