bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insights About Cannabis and Psychosis Using Video Games for Young People With a First Episode of Psychosis, Particularly Those From Black Racialized Communities: Protocol for a Mixed Methods Study
Authors: Archie Suzanne , Palaniyappan Lena , Olagunju Andrew T , Johnson Natasha , Kozloff Nicole , Sadeh Elham , Bardell Andrea , Baines Alexandra , Anderson Kelly K , Ayonrinde Oyedeji , Ferrari Manuela 
Published: April 2022

Background
Cannabis use disorder among young people with a first episode of psychosis contributes to relapse, hospitalization, and impaired functioning. However, few studies have examined what young people with early phase psychosis, particularly those from Black racialized communities, understand or appreciate about this relationship, even though they may be at risk. There are no formally tested knowledge translation strategies that disseminate these research findings for young people with emerging psychosis from Black racialized communities.

Objective
This study aims to conceptualize what young people with early phase psychosis/cannabis use disorder understand about the relationship between cannabis and psychosis, focusing on people from racialized backgrounds. This study also aims to assess whether the knowledge translation product, the “Back to Reality Series,” increases awareness of the impact of cannabis use on psychosis from the perspectives of young people with emerging psychosis and cannabis use disorder from Black African and Caribbean communities.

Methods
Qualitative analysis will reveal themes from qualitative interviews about cannabis and psychosis from the perspectives of young people with emerging psychosis and cannabis use disorder from Black African and Caribbean communities. Perceptions before and after exposure to the Back to Reality Series will be qualitatively analyzed. A control game will be used for comparison, and scores on a quiz after playing the Back to Reality Series will be quantitatively analyzed to establish whether the Back to Reality Series raises awareness of the effects of cannabis on psychosis. An advisory council involving young people from Black communities, family members, and clinicians will bring community perspectives to this research.

Results
We began recruiting participants for this study in September 2021. We will complete data collection on demographic and clinical factors, qualitative interviews, and quantitative assessments of the Back to Reality Series.

Conclusions
The voices of young people from racialized backgrounds will generate preliminary data to inform early psychosis programs, addressing cannabis use in this population. The findings may advance the use of a new knowledge translation product that deals with gaps in knowledge about cannabis use for people experiencing early phase psychosis, particularly those from racialized communities.

International Registered Report Identifier (IRRID)
DERR1-10.2196/36758
The Knowledge Assessment of Renal Transplantation (KART) 2.0
Authors: Waterman Amy D. , Nair Devika , Purnajo Intan , Cavanaugh Kerri L. , Mittman Brian S. , Peipert John Devin 
Published: April 2022

Background and objectives
Many individuals with kidney disease, particularly those belonging to racial and ethnic minority groups and whose primary language is not English, lack knowledge related to kidney disease symptoms, physiologic functions of the kidney, and benefits and risks of kidney transplantation. Valid instruments to assess patients’ knowledge of CKD and kidney transplantation are needed.

Design, setting, participants, & measurements
Using a sample of 977 patients with stages 3–5 CKD in the Kaiser Permanente health system, we developed the Knowledge Assessment of Renal Transplantation (KART) 2.0 instrument. We conducted cognitive interviews followed by item response theory (IRT) to reduce 48 candidate items. Construct validity was tested by examining differences in scores between patients who spent <1 and ≥1 hour receiving CKD and transplant education.

Results
Cognitive interviews modified four items and omitted 11. IRT analyses resulted in two scales: the KART 2.0–Transplant Knowledge Scale (16 items; Cronbach’s α=0.8) and the KART 2.0–CKD Knowledge Scale (nine items; Cronbach’s α=0.79). Differential item functioning showed that the scales were unbiased to capture knowledge across self-identified race, primary language, CKD stage, and sex. Both scales distinguished patients who had spent <1 and ≥1 hour speaking with health professionals (effect size [ES]=0.33 [transplant], 0.54 [CKD]; P<0.001 for both), reading about kidney disease (ES=0.45 [transplant], 0.62 [CKD]; P<0.001), reading about kidney transplantation (ES=0.67 [transplant], 0.69 [CKD]; P<0.001), and reading about living donor kidney transplant (ES=0.76 [transplant], 0.62 [CKD]; P<0.001).

Conclusions
The KART 2.0 is a valid tool to assess patients’ knowledge of CKD and kidney transplantation.
Rokok Dan Hipertensi
Authors: Rachmawati Faika , Puspita Tities , Suryatma Anton 
Published: April 2022

Hypertension was one of the non-communicable diseases that may cause death in Indonesia. Through Healthy Indonesia Program with Family Approach (PIS-PK), the public health centers conduct home visits to collect family’s health status, such as risk factors and health outcomes involving smoking and hypertension. This study investigates the correlation of smoking and hypertension in two heath centers to the lowest and highest healthy family index (IKS) in Metro City, Lampung Province. The data analysis used multiple logistic regression. The results indicated Puskemas Mulyojati had 11.18% of people diagnosed with hypertension, while Puskesmas Iringmulyo had 5.14%. More smokers were higher in Mulyojati (27.30%) than those in Iringmulyo (23.38%). The proportion of smokers with hypertension in Mulyojati was 2.40% (OR 0.70; 95%CI 0.59-0.84; p 0.006) and in Iringmulyo was 1.09% (OR 0.87 95%CI 0.66-1.14; p 0.115). In Mulyojati, the odds of smokers contracting hypertension was 0.56 times lower than the non-smokers (95%CI 0.44-0.71; p <0,000); meanwhile, the smoking-hypertension relationship in Iringmulyo was not significant despite a bigger odds ratio (OR 0.83, 95%CI 0.59-1.17; p 0.293.) As a recommendation, both Puskesmas promote campaigns for a smoke-free movement, smoke-free areas and smoking cessation counseling to reduce the prevalence of hypertension.
Abstrak
Hipertensi merupakan salah satu penyakit tidak menular penyebab kematian di Indonesia. Melalui Program Indonesia Sehat dengan Pendekatan Keluarga (PIS-PK), puskesmas melakukan kunjungan rumah dan mengumpulkan data profil kesehatan keluarga, meliputi faktor risiko dan kejadian penyakit termasuk kebiasaan merokok dan hipertensi. Penelitian ini bertujuan mengetahui hubungan antara kebiasaan merokok dengan hipertensi di dua puskesmas yang memiliki Indeks Keluarga Sehat (IKS) terendah dan tertinggi di Kota Metro, Provinsi Lampung. Data dianalisis dengan regresi logistik berganda. Sebanyak 11,18% orang di Puskesmas Mulyojati didiagnosis hipertensi, sedangkan Puskesmas Iringmulyo sebesar 5,14%. Perokok lebih banyak ditemukan di Puskemas Mulyojati (27,30%) daripada di Puskesmas Iringmulyo (23,38%). Proporsi orang yang merokok dan didiagnosis hipertensi di Puskesmas Mulyojati sebanyak 2,40% (OR 0,70; IK 95% 0,59-0,84; p 0,000) sedangkan di Puskesmas Iringmulyo 1,09% (OR 0,87; IK 95% 0,66-1,14; p 0,325). Odd rasio orang merokok untuk mengidap hipertensi 0,56 kali dibandingkan dengan orang yang tidak merokok dengan hasil signifikan (IK 95% 0,44-0,71; p <0,000) di Puskesmas Mulyojati. Di Puskesmas Iringmulyo, meskipun odd rasionya sebesar 0,83, namun hasilnya tidak signifikan (IK 95% 0,59-1,17; p 0,293). Kedua Puskesmas disarankan untuk melakukan kampanye gerakan tanpa asap rokok, area bebas rokok dan konseling berhenti merokok untuk menurunkan prevalensi hipertensi.
Persepsi Mahasiswa UIN Walisongo Terhadap Covid-19 Dan Perilaku Kesehatan
Authors: Ramadhana Shela Delfia , Fadlilati Dian , Hidayatullah Ahmad Fauzan , Norra Bunga Ihda , Hariz Anif Rizqianti 
Published: April 2022

Covid-19 is a disease caused by the coronavirus. Since the end of 2019, WHO has reported cases of pneumonia that occurred in Wuhan, Tiongkok, which then spread to several countries including Indonesia. The number of the spread of Covid-19 is increasing day by day, the government continues to try to break the chain of the spread of Covid-19. The success of efforts to break the Covid-19 chain depends on the public's knowledge and perception of Covid-19 and its prevention efforts. This study aims to determine the perceptions and behavior of UIN Walisongo students in preventing Covid-19. This study used a quantitative descriptive research method, with a data collection instrumen in the form of a questionnaire. Data collection techniques using a google form questionnaire with 10 statements and opinions from UIN Walisongo students. The study population was all students of UIN Walisongo Semarang and as a sample were 302 students from various faculties who were selected by nonprobability sampling. The results showed 86.49% of the students of UIN Walisongo have a "very good" perception of Covid-19. Healthy behaviors carried out by UIN Walisongo students as an effort to prevent Covid-19 include: washing hands, using masks, social distancing, taking vitamins and exercising. To increase the prevention of Covid-19, it is necessary to conduct health education directly or online through social media to communicate with the public.
Abstrak

Covid-19 merupakan penyakit yang disebabkan oleh virus corona. Pada akhir tahun 2019, WHO melaporkan kasus pneumonia yang terjadi di Wuhan, Tiongkok yang kemudian menyebar di beberapa negara termasuk Indonesia. Angka penyebaran Covid-19 semakin hari kian meningkat, pemerintah terus berupaya memutus rantai penyebaran Covid-19. Keberhasilan upaya pemutusan rantai Covid-19 tergantung dari pengetahuan dan persepsi masyarakat terhadap Covid-19 serta upaya pencegahannya. Penelitian ini bertujuan untuk mengetahui persepsi dan perilaku Mahasiswa UIN Walisongo dalam pencegahan Covid-19. Penelitian ini menggunakan metode penelitian deskriptif kuantitatif, dengan instrument pengumpulan data berupa kuesioner. Teknik pengumpulan data dengan menggunakan kuesioner google form dengan 10 pernyataan serta pendapat dari mahasiswa UIN Walisongo. Populasi penelitian adalah seluruh mahasiswa UIN Walisongo Semarang dan sebagai sampel adalah 302 mahasiswa dari berbagai fakultas yang dipilih dengan teknik nonprobability sampling. Hasil penelitian menunjukkan 86.49% mahasiswa UIN Walisongo mempunyai persepsi “sangat baik” terhadap Covid-19. Perilaku sehat yang dilakukan mahasiswa UIN Walisongo sebagai upaya pencegahan Covid-19 meliputi: cuci tangan, menggunakan masker, social distancing, mengonsumsi vitamin dan berolahraga. Untuk meningkatkan pencegahan Covid-19 perlu dilakukan penyuluhan kesehatan secara langsung atau online melalui media sosial untuk berkomunikasi dengan masyarakat.
Analisis Kualitatif Peran Ibu Terhadap Pencegahan COVID-19 Dan Pemberian Gizi Pada Masa Pandemi
Authors: Purnama Tri Bayu , Pasaribu Rahayu Sakinah , Siregar Kaaf Wajiah , Roszaliya Eka Githa 
Published: April 2022

More than two million children suffer from malnutrition and more than 7 million children under the age of 5 suffer from stunted growth. Nutritional status is important as it is a risk factor for morbidity and mortality. The role of mothers is required to monitor the nutritional status of young children during the COVID-19 pandemic. This study aims to determine the role of mothers in monitoring the nutritional status of young children during the COVID-19 pandemic. In this study, a qualitative approach was used to describe maternal activities in monitoring infant nutritional status during the pandemic. Data collection was carried out through in-depth interviews using a questionnaire as an interview guide. The whistleblower research was conducted in Medan City with up to 4 people as an area with a high COVID-19 prevalence rate and with Sibolga City with up to 6 whistleblowers as a comparison city with a low COVID-19 prevalence in North Sumatra province. This study found that the whistleblowers still had not implemented the COVID-19 prevention protocol, e.g. B. by not cleaning items frequently touched with disinfectants because they did not have disinfectant, did not feel the need to be cleaned regularly and lacked knowledge. Most of the whistleblowers had given their young children balanced diets during the COVID-19 pandemic, but some of the whistleblowers found restrictions on eating vegetables and fruits.
Abstrak
Lebih dari dua juta anak menderita gizi buruk dan lebih dari 7 juta anak di bawah usia 5 tahun mengalami stunting. Status gizi penting karena merupakan salah satu faktor risiko terjadinya kesakitan dan kematian. Peran ibu dibutuhkan untuk memantau status gizi pada balita selama pandemi COVID-19. Penelitian ini bertujuan untuk mengetahui peran ibu terhadap pemantauan status gizi balita pada masa pandemi COVID-19. Pendekatan kualitatif digunakan pada penelitian ini untuk mendeskripsikan kegiatan yang dilakukan oleh ibu dalam pemantauan status gizi bayi pada masa pandemi. Pengumpulan data dilakukan dengan wawancara mendalam dengan menggunakan kuesioner sebagai panduan wawancara. Informan penelitian dilakukan pada Kota Medan sebanyak 4 orang sebagai daerah dengan tingkat penyebaran COVID-19 yang tinggi dan Kota Sibolga sebanyak 6 informan sebagai kota pembanding dengan penyebaran COVID-19 rendah di Provinsi Sumatera Utara. Penelitian ini menemukan bahwa informan masih belum menerapkan protokol pencegahan COVID-19 seperti tidak membersihkan barang-barang yang sering disentuh dengan disinfektan dikarenakan tidak punya disinfektan, tidak merasa perlu untuk dibersihkan secara berkala, dan kurangnya pengetahuan. Sebagian besar informan sudah memberi balita makanan gizi seimbang di masa pandemi COVID-19 tetapi ditemukan keterbatasan dalam konsumsi sayur dan buah pada beberapa informan.
PENGEMBANGAN MEDIA BERBASIS LECTORA INSPIRE PADA PEMBELAJARAN KOREKSI BENTUK WAJAH
Authors: Tobing Marnala , Irena Devy , Sari Dian Maya , Vebibina Almaida 
Published: April 2022

Abstrak : Penelitian ini bertujuan untuk menghasilkan produk media berbasis lectora yang layak digunakan pada materi koreksi bentuk wajah. Jenis penelitian yang digunakan ialah research and development (R&D) yang dimana dibatasi pada tahapannya berdasarkan dengan tujuan penelitian, yaitu: (1) analisis kebutuhan; (2) pengumpulan data; (3) desain produk; (4) validasi ahli materi dan media dan produk akhir. Subjek penelitian ini adalah siswa kelas X Tata Kecantikan SMK AKP Galang. Instrumen penelitian menggunakan lembar kuestioner. Teknik analisis data pada penelitian ini menggunakan deskriptif kuantitatif. Hasil penelitian berdasarkan : (1) Uji ahli materi, (2) Uji ahli media. Hasil perolehan nilai rata-rata uji coba produk sebesar 92,3% dengan kategori “sangat baik”. Kata kunci: media pembelajaran, lectora inspire, koreksi bentuk wajah Abstract : This research aims to produce lectora-based media products that are worth using in facial shape correction materials. The type of research used is research and development (R&D) which is limited to its stages based on the purpose of research, namely: (1) needs analysis; (2) data collection; (3) product design; (4) validation of material and media experts and the final product. The subject of this study is a student of class X Tata Beauty SMK AKP Galang. Research instruments use a cookie sheet. The data analysis techniques in this study use quantitative descriptive. The results of the study are based on: (1) Test material experts, (2) Test media experts. The average product trial score was 92.3% with an "excellent" category. Keywords: learning media, lectora inspire, correction of face shape
REGULARITIES OF PHYSICO-CHEMICAL INTERACTION IN THE QUASIBINARY SYSTEMS BASED ON THE TERNARY HALIDES Rb3(Cs3)Sb2(Bi2)Br9(I9) AND K2(Rb2,Cs2,Tl2)TeBr6(I6): EXPLANATION WITHIN THE FRAMEWORK OF THE BOND VALENCE MODEL
Authors: Sidey V.I. 
Published: April 2022

The work is the first attempt to employ the bond valence model (BVM) in the explanation and interpretation of the phase diagrams observed for the quasibinary systems based on the ternary halides Rb3(Cs3)Sb2(Bi2)Br9(I9) (A3B2X9) and K2(Rb2,Cs2,Tl2)TeBr6(I6) (A2BX6) belonging to the structural family of perovskite. The most characteristic features of the phase diagrams of such systems are (a) a monotonic increase in the melting and crystallization temperatures when the smaller A atom is replaced by a larger chemical analogue; (b) a gradual decrease in the melting and crystallization temperatures when the bromine atoms are replaced by iodine atoms, reaching the temperature minimum at a molar ratio of ~1 : 1, and then an increase of the temperatures to the pure iodine component of the system. With the isostructurality of the starting components, in case (a) a continuous series of solid solutions (CSSS) of substitution is formed, without a temperature minimum; if the starting components belong to different structural types, then a peritectic interaction with the wide concentration limits of solid solutions is observed. Under the same conditions concerning the isostructurality/non-isostructurality of starting components, in case (b), correspondingly, either a CSSS of substitution with a temperature minimum is formed or eutectic interaction with the wide concentration limits of solid solutions is observed.
Within the framework of the BVM, in case (a) a monotonic increase of the melting and crystallization temperatures when replacing a smaller atom A with a larger analogue can be interpreted as a consequence of reducing the deficit of the bond valence sum (BVS) for cations A, resulting in the stabilization of the structure as a whole. In case (b), partial replacement of one halogen ion by a halogen ions of another sort leads either to a deficit (if a larger anion is replaced by a smaller one) or to an excess (if a smaller anion is replaced by a larger one) of the BVS values for the cations A and for the anion that replaced the main halogen sort. An increase in the excess or deficit of the BVS values destabilizes the structure of ternary halides, reducing the melting and crystallization temperatures; the maximum destabilization is achieved at a ~1 : 1 molar ratio of the components, which is expressed in reaching the characteristic temperature minimum of the respective systems.
The approach described in the work can expectedly be employed in explanation and interpretation of another phase diagrams based on the structures featuring the closest packing formed by alkaline metals and halogens.
Keywords: ternary halides; crystal structures; phase diagrams; bond valence model.
THE X-RAY DIFFRACTION ANALYSIS OF A COMPLEX OXIDE CATALYST OF 50%Cu3(PO4)2•50%Ni3(PO4)2
Authors: Golub N.P. , Golub E.O. , Hurch A.V. , Kozma A.A. , Solomon A.M. , Kuznietsova A.O. 
Published: April 2022

Preparation of initial orthophosphates of Copper (II) and Nickel (II) and a complex catalytic system based on them 50 % Cu3(PO4)2∙50 % Ni3(PO4)2 was carried out according to the methods developed at the Department of Physical and Colloid Chemistry, of Uzhhorod National University. The synthesized system was investigated by X-ray phase analysis. Experimental diffraction patterns show that air-dry samples of the initial components and the intermediate sample of 50%Cu3(PO4)2∙3H2O•50%Ni3(PO4)2∙8H2O are very different from each other. This gives grounds to assume that the air-dry phosphate of the catalytic system 50%Cu3(PO4)2∙3H2O•50%Ni3(PO4)2∙8H2O can be characterized as a new phase. Annealing of the obtained air-dry complex sample in the temperature range 120-700ºС leads to the corresponding physicochemical transformations. Experimental data show that the structure of the formed intermediate air-dry sample after heat treatment undergoes significant changes. At the same time, heat treatment leads to gradual partial or complete dehydration of a complex catalytic system. When 600ºC is reached, the dry X-ray amorphous catalyst begins to crystallize. This is due to the gradual dehydration of the catalyst at lower temperatures with the loss of much of the chemically bound water and the transition to the amorphous state. The process of forming the crystal structure of the dehydrated complex sample is significantly intensified when reaching 700ºC. Thus, the calcination of the synthesized phosphate phase in the specified temperature range allows not only to carry out its complete dehydration, but also, to a large extent, promotes the gradual crystallization of the dehydrated phase. In turn, this causes the formation on the surface of the synthesized complex copper-nickel phosphate catalyst system of 50%Cu3(PO4)2∙3H2O•50%Ni3(PO4)2∙8H2O acid active centers of appropriate strength. It was also found that if necessary to obtain a fully dehydrated and crystallized copper-nickel-phosphate sample, the duration of calcination at a final temperature of 700ºC should be carried out more than 1 hour.
Keywords: X-Ray Diffraction (XRD) analysis; catalysts; сopper (II) orthophosphate; nickel (II) orthophosphate; catalytic 50 % Cu3(PO4)2∙50 % Ni3(PO4)2 system.
Ochratoxin A potentiates citrinin accumulation in kidney and liver of rats
Authors: Rašić Dubravka , Stefanović Srđan , Milićević Dragan , Mladinić Marin , Želježić Davor , Pizent Alica , Konjevoda Paško , Peraica Maja 
Published: April 2022

Abstract
Ochratoxin A (OTA) and citrinin (CTN) are nephrotoxic mycotoxins often found together in grain. The aim of this study was to measure their accumulation in the kidney and liver of adult male Wistar rats, see how it would be affected by combined treatment, and to determine if resveratrol (RSV) would decrease their levels in these organs. The rats received 125 or 250 mg/kg bw of OTA by gavage every day for 21 days and/or 20 mg/kg bw of CTN a day for two days. Two groups of rats treated with OTA+CTN were also receiving 20 mg/kg bw of RSV a day for 21 days. In animals receiving OTA alone, its accumulation in both organs was dose-dependent. OTA+CTN treatment resulted in lower OTA but higher CTN accumulation in both organs at both OTA doses. RSV treatment increased OTA levels in the kidney and liver and decreased CTN levels in the kidney. Our findings point to the competition between CTN and OTA for organic anion transporters 1 and 3.
Effects of naringin and valproate interaction on liver steatosis and dyslipidaemia parameters in male C57BL6 mice
Authors: Jutrić David , Đikić Domagoj , Boroš Almoš , Odeh Dyna , Drozdek Sandra Domjanić , Gračan Romana , Dragičević Petar , Crnić Irena , Jurčević Irena Landeka 
Published: April 2022

Abstract
Valproate is a common antiepileptic drug whose adverse effects include liver steatosis and dyslipidaemia. The aim of our study was to see how natural flavonoid antioxidant naringin would interact with valproate and attenuate these adverse effects. For this reason we treated male C57BL6 mice with a combination of 150 mg/kg of valproate and 25 mg/kg naringin every day for 10 days and compared their serum triglycerides, cholesterol, LDL, HDL, VLDL, and liver PPAR-alpha, PGC-1 alpha, ACOX1, Nrf2, SOD, CAT, GSH, and histological signs of steatosis. Valproate increased lipid peroxidation parameters and caused pronounced microvesicular steatosis throughout the hepatic lobule in all acinar zones, but naringin co-administration limited steatosis to the lobule periphery. In addition, it nearly restored total serum cholesterol, LDL, and triglycerides and liver ACOX1 and MDA to control levels. and upregulated PPAR-alpha and PGC-1 alpha, otherwise severely downregulated by valproate. It also increased SOD activity. All these findings suggest that naringin modulates key lipid metabolism regulators and should further be investigated in this model, either alone or combined with other lipid regulating drugs or molecules.