bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiac Rehabilitation Program with High Intensity Aerobic Exercise Can Reverse Diastolic Impairment in Patients Undergoing Coronary Artery Bypass Surgery
Authors: Rai Alireza , Bahremand Mostafa , Salehi Nahid , Rezaee Mansour , Raeisei Ahmad Ali 
Published: January 2022

Background: Cardiac rehabilitation is known as a powerful non-pharmacological approach for improving functional capacity, and left ventricular systolic function; however, some limited data have suggested an attenuation of the decline in diastolic function with this program. This study investigated the effect of high intensity aerobic exercise following coronary artery bypass surgery (CABG) on diastolic dysfunction.
Materials and Methods: Forty four patients with different levels of diastolic dysfunction who underwent CABG surgery were included. The participants attended the complete cardiac rehabilitation program three times per week for two months (totally 24 sessions). The patients underwent complete transthoracic echocardiographic studies including two-dimensional and spectral Doppler echocardiography immediately before attending rehabilitation program and also after the completion of rehabilitation sessions.
Results: There was a significant decrease of isovolumic relaxation time (IVRT) after participating complete cardiac rehabilitation (94.0 to 89.0; P=0.001). The diastolic function parameters of early diastolic mitral inflow peak velocity to late diastolic mitral inflow peak velocity (E/A) ratio (0.94 to 1.04; P=0.001), deceleration time (DT) of the mitral E wave (192.7 to 219.0; P=0.011), and velocity of early diastolic mitral annular motion (Ea) (5.9 to 6.7; P=0.026) were improved after the rehabilitation, whereas mitral A duration to pulmonary A duration (MAD/PAD) ratio was slightly improved (1.07 to 1.12; P=0.056) and pulmonary veins systolic flow to pulmonary vein diastolic flow (PVS/PVD) ratio (0.89 to 1.04; P=0.345) remained unchanged.
Conclusion: A complete cardiac rehabilitation program with high intensity aerobic exercise approach can reverse diastolic impairment in patients undergoing CABG.
Assessment of Musculoskeletal Disorders Between lorry Drivers in Qom, Iran
Authors: Mozafari Abolfazl , Najafi Mohsen , Vahedian Mostafa , Mohebi Siamak 
Published: January 2022

Background: Musculoskeletal disorders represent a substantial cause of morbidity worldwide. The contribution of work to these disorders has been well established by various epidemiological and laboratory-based researches. The aim of this study is to investigate the prevalence and associated factors of musculoskeletal disorders in truck drivers.
Materials and methods: This cross sectional study included truck drivers referred to Transportation Company in Qom province. We evaluated musculoskeletal disorders by Nordic questionnaire and demographic data. The questionnaire was filled by direct interview. Data analysis was done in SPSS and P value below Â 0.05 was significant.
Results: Age of 173 male participated in this study was 38.82 years with body mass index (BMI) of 26.02 (Kg/m2) and mean work duration of 8.85 years. In the period of past week and past year, prevalences of musculoskeletal disorders at all of the nine body regions of drivers were 56.6% and 78.6%, respectively. The most common musculoskeletal involvement was lumbar, back and neck regions. There were significant relationship among musculoskeletal problems with age, work duration, and BMI (P<0.05).
Conclusion: This investigation showed the importance of frequent musculoskeletal disorders among Â drivers in different body regions particularly in lumbar area and its Â correlation with work duration, high weight, and age.
Effects of Carnitine with and without Glutamine Supplementation on Markers of Muscle Damage and Muscle Soreness among Football Players: A Randomized Controlled Clinical Trial
Authors: Mohtadinia Javad , Hozoori Mohammad , Babaei Hossein , Arefhosseini Seyedrafie , Kooshavar Hossein , Sabour Siamak 
Published: January 2022

Background: Exercise-induced muscle damage can affect exercise performance. The purpose of this study is to examine the effects of Carnitine and Glutamine supplementation on markers of muscle damage and muscle soreness after physical exertion on football players.Materials and Methods: Twenty eight healthy male football players aged 21.1Â±0.7 were recruited in a double blind, randomized, placebo-controlled clinical trial on 3 weeks of supplementation. Before supplementation protocol, each participant had to run on a treadmill for 30 minutes at 75% VO2max. Participants were randomly divided into 4 groups: L-Carnitine, L- Glutamine, L-Carnitine plus L- Glutamine and placebo. Blood samples were obtained pre-exercise and immediately after exercise. Muscle soreness was assessed on both occasions and two days after each exercise.Results: L-Carnitine and L-Glutamine supplementation for 21 days significantly decreased Creatine Kinase activity as a marker of muscleâ€™s damage before (P=0.014) and after exercise (P=0.047), and muscle soreness two days after physical exertion (P=0.057). However, Lactate Dehydrogenase activity was affected by Carnitine supplementation after exercise.Conclusion: Chronic oral supplementation of Carnitine and Glutamine before exercise can reduce chemical markers of muscle tissue damage after exercise. In addition, these supplements may reduce muscle pain after exercise and optimize the processes of muscle tissue repair.[GMJ. 2014;3(4):207-15]
Burnout and Socio-demographic Characteristics of Nurses in Iran
Authors: Rashedi Vahid , Rezaei Mohammad , Gharib Masoud 
Published: January 2022

Background: Nursing is considered as a profession at risk for high levels of stress and burnout, and these levels may be increasing as the care they deliver becomes complex. The purpose of this study was to investigate the relationship between burnout and socio-demographic characteristics of nurses.Materials and Methods: A cross-sectional descriptive-analytical design was used. The sample consisted of 194 nurses working in five hospitals of Hamadan University of Medical Sciences in Iran, who completed the Maslach Burnout Inventory (MBI) as well as a socio-demographic questionnaire. The data were analyzed using descriptive statistics, Pearson correlations, independent t-test and ANOVA.Results: Results indicated moderate levels of emotional exhaustion, depersonalization and low levels of personal accomplishment. There was significant relationship between burnout and age, length of employment, and educational level.Conclusion: Identifying an integrative process of burnout among nurses is an essential step in developing effective managerial strategies in order to address the problem. To prevent burnout, further research is necessary to determine the factors associated with it so that recommendations can be made for future wellness interventions. [GMJ. 2014;3(4):232-7]
The Effect of Isometric Exercises on Primary Dysmenorrhea: A Randomized Controlled Clinical Trial
Authors: Azima Sara , Rajaei Bakhshayesh Hajar , Abbasnia Keramatollah , Kaviani Maasumeh , Sayadi Mehrab 
Published: January 2022

Background: Primary dysmenorrhea is the most common cyclic pelvic pain and is also the most common gynecological problem worldwide and affects quality of life. The present study aimed to investigate the effect of isometric exercises on intensity and duration of pain and level of anxiety in the students with primary dysmenorrhea.
Materials and Methods: In this randomized controlled clinical trial, 68 students living in dormitories of Shiraz University with primary dysmenorrhea Â were randomly assigned to isometric exercises and control groups. The intervention group performed isometric exercises since the third day of the menstrual cycle for 8 weeks. Pain intensity was measured using Visual Analog Scale (VAS). In addition, the anxiety level was assessed using Spielberger questionnaire. The data were analyzed using independent t-test, repeated measures ANOVA, and Bonferroni Post hoc test at the end of the second and third months of the study. Besides, P<0.05 was considered as statistically significant.
Results: Pain intensity and duration of pain was significantly reduced in exercises group (p<0.001). However, no significant difference was found between the two groups concerning the mean anxiety levels.
Conclusion: Primary dysmenorrhea is a common complaint among young women. Isometric exercises seem to be an easy, non-pharmacological method for reducing primary dysmenorrheal.
Post publication peer review in Iranian biomedical journals
Authors: Derakhshan Rad Seyed-Alireza , Ghanbari Ali 
Published: January 2022

Background: letters to the editor provide an opportunity for readers to state their views about published articles. Research on this issue has been mainly on western journals and there is no study on the Iranian journals. The present study aimed to investigate this subject in Iranian biomedical journals.
Materials and Method: This was a bibliometric study. The databases of Iran Medex, Medlib, and SID were searched to find the letters published in Iranian biomedical journals. The letters in formats such as commentaries, concise articles, and the preliminary results of studies or brief reports were excluded from the study.
Results: 184 letters were found in Iranian journals; 49 of them were responses of authors to the criticism made by readers. As a result, the number of letters that commented on or criticized the original articles reduced to 135. For every 1198 articles published in Iranian journals, there is only one letter written in correspondence to published articles. 76% of letters published in 2010 to 2012.
Conclusions: the Iranian readers are much less productive in writing letters to Iranian biomedical journals compared to their peers in other places. The low number of letters could be attributed to several issues including a broad unawareness of the importance of the letters and little incentive for writing letter.The sharp rise in the number of letters after 2009 indicates a boosted motivation of Iranians for writing more letters to the editor.
The Prevalence and the Resistance Profile of Methicillin-Resistant Staphylococcus aureus Colonized in the Nostrils of Cancer Patients in Namazi Teaching Hospital, Shiraz, Iran, 2011-12
Authors: Motamedifar Mohammad , Hassanzadeh Razyeh , Kandehkar Ghahraman Mohammad Reza , Ashrafzadeh Abdolsamad , Hashemizadeh Zahra 
Published: January 2022

Background: Methicillin-resistant (MRSA) Staphylococcus aureus (S. aureus) are responsible for a vast number of nosocomial infections especially in immunocompromised subjects such as cancer patients. The presence of comorbidities including malignancies has been associated, with S. aureus bacteremia mortality. Thus, the detection of MRSA in this patients and the antibiotic susceptibility pattern of the isolates eases the selection of first-line medications and the prevention from further complications in cancer patients. The aim of this study was to determine the prevalence of MRSA infection and antibiotic susceptibility patterns of the isolates in pre and post-chemotherapy course in cancer patients.
Materials and Methods: From May 2011 to July 2012, 200 nostril samples of cancerous patients were obtained and cultured on blood agar plates. After isolation and confirmation of S. aureus, antibiotic resistance pattern of the isolates was determined pre-chemotherapy and after the chemotherapy against vancomycin, tigecycline, linezolid, chloramphenicol, and oxacillin using disk diffusion test following CLSI guidelines. Chi-square test was used for data analysis.
Results: Among a total number of 200 various cancer patients (64.5% females), 42 (21%) cases were positive for S. aureus and 7 (3.5 %) were MRSA carriers. Mean ages of MSSA and MRSA infected patients were 50.97Â±15.94 and 53.57Â±18.28 years old, respectively. In vitro susceptibility pattern of the MRSA and MSSA isolates to the 4 tested agents did not differed significantly after the chemotherapy in contrast with pre-chemotherapy state.
Conclusions: This study showed that chemotherapy does not change the susceptibility pattern of MRSA species to antibiotics of choice in cancer patients. However, the importance of controlling methicillin resistant staphylococcal infections in critical cases, specifically cancer cases, necessitates the early detection, further investigations on more effective medications.
Satisfaction of Family Physician Plan: Viewpoint of Physicians and Health Service Consumers in Kerman, Southeast of Iran
Authors: Ahmadi Batoul , Pourebrahimi Mohammad Hossein , Ram Bejandi Malihe , Ram Bejandi Malihe , Sadeghi Ahmad , Khammarnia Mohammad , Siavashi Elham 
Published: January 2022

Background: Family Physician plan is known as one of the most appropriate strategies to implement rural health insurance program in the form of referral system in Iran. This study aims to determine the satisfaction of family physicians and service consumers and its causes of dissatisfaction in the South of Iran. Materials and Methods: This cross-sectional study was performed in Kerman Health Network. Nineteen family physicians and 370 service consumers were selected using stratified random sampling. Data was gathered using two standardized questionnaires. Frequency tables, frequency percentage, mean graphs, Z and Freedman statistical tests were used to analyze the data. Results: Mean scores of physiciansâ€™ satisfaction were 9.10 and 4.12 in staff performance and payment system, respectively. Service consumers were satisfaction of physician delivery care (7.25), and para-medical (3.61). Moreover, most physicians were interested in per capita (31/6%). Conclusion: Family physician and health service consumers are highly satisfied. Satisfaction is an important factor for ensuring service quality and any ignorance in this regard can reduce the quantity and quality of delivered care. Physicians are recommended to respect their consumers and consider their waiting time. Meanwhile, health system managers should promote physiciansâ€™ payment. [GMJ.2015;4(2):96-102]
Evaluation of Serum Catalase Activity and Malondialdehyde Level as Stress Oxidative Biomarkers among Iranian Welders
Authors: Sattarahmady Naghmeh , Heli Hossein , Mehdizadeh Ali Reza , Yarmohammadi Hossein , Mortazavi Seyed Mohammad Javad 
Published: January 2022

Background: Oxidant/antioxidant imbalance results in oxidative stress which plays a major Â role in many diseases. Inhalation of metal-enriched fumes and exposure to electromagnetic Â fields of welding device could induce oxidative stress in welders. Therefore, it is necessary to determine the level of oxidative stress among welders. Our study is aimed at estimating serum catalase and Malondialdehyde (MDA) levels in Iranian welders. Materials and Methods: Serum catalase activity and MDA levels were measured in 30 Iranian welders and 30 healthy non-welder subjects via catalase and MDA kit (Abcam). Results: The catalase activity (mU/L) and MDA levels (nmol/mL) were found to be 7.19Â±2.30 and 0.97Â±0.55, respectively in welder subjects, 10.73Â±1.08, and 0.58Â±0.38 in the control subjects. Catalase activity among welders was significantly lower than the control subjects (P<0.0001). In addition, plasma MDA level was significantly higher in welders, compared to the control subjects (P=0.0028). There was no significant difference between welder subgroups when the catalase activity and plasma MDA levels were compared. Conclusion: This study indicates that oxidant/antioxidant balances alter in Iranian welders. In other words, these results imply that the threshold limit of the resistance of the welder body against oxidative stress and damage has decreased. [GMJ. 2015;4(3):62-66]
Combined Factor V and Factor VIII Deficiency: A Case Report
Authors: Shahverdi Ehsan , Abolghasemi Hassan , Dolatimehr Fardin , Beheshtian Sara , Chaeichi Shima Melatshahi , Masoumi Avishan 
Published: January 2022

Background: Combined factor V and factor VIII deficiency (F5F8D, OMIM 227300) is a rare autosomal recessive bleeding disorder. It seems more common among Jews and Iranians, particularly in regions with frequent consanguineous marriages. Case Report: We describe a 5-yearoldÂ girlÂ bornÂ outÂ ofÂ consanguineousÂ marriageÂ withÂ aÂ complaintÂ ofÂ prolongedÂ bleedingÂ after dental extraction. There were no history of spontaneous bleeding and other coagulation defect symptoms. Conclusion: In frequent consanguineous marriage regions, inherited deficiency of factor V and VIII should be considered in patients with coagulation defect symptoms.[GMJ. 2016;5(1):42-44]
Correlation Between Body Image and Sleep Quality in Patients with Congestive Heart Failure in the Sari City, North of Iran
Authors: Goudarzian Amir Hossein , Beik Sima , Zamani Fatemeh , Heidari Gorji Alimorad , Ranjbar Mansour 
Published: January 2022

Background: The present study was conducted aimed to determine the relationship between body shape and sleep quality in patients with congestive heart failure.
Materials and Methods: In this descriptive-correlation study which was conducted in 2015, 290 patients with congestive heart failure were recruited using the simple random sampling method. Data were collected through the demographic information form (including age, sex, marital status, economic level and education), medical (age, sex, adequacy of economic level, education, history of hypertension and drug use, family history of heart disease and depression in the family, activity and history of special disease), Body Shape Questionnaire (BSQ-34) and Pittsburgh Sleep Quality Index (PSQI). SPSS 20.0 (SPSS Inc., Chicago, IL, USA) were utilized for data analysis with descriptive and inferential statistics tests (Generalized Linear models with bonferroni correction).
Results: Based on results only 48 patients with 4.31 (SD: 0.94; 95%CI: 4.03-4.58) mean score of Pittsburgh Sleep Quality Index Â had a good levels of sleep quality. The mean score of the Body Shape Questionnaire of patients were 122.47 (SD: 19.157; 95%CI: 12.25-124.68).
Conclusion: According to the present study, the sleep quality and body shape of the patients with CHF from their body were weak. It is therefore necessary to do something in order to remove the backgrounds of sleep disorders in these patients as well as the need to more detailed investigation to determine the exact relationship of these two variables.
Epidemiology of Stroke in Iran
Authors: Ghandehari Kavian 
Published: January 2022

Numerous hospital-based stroke registries have been developed in Iran during last decade. Khorasan Stroke Registry, Khorasan Posterior Circulation Stroke Registry, Khorasan Pediatric Stroke Registry and Khorasan Stroke in Young Adults Registry are among these published registries. Meanwhile, There is only one epidemiologic deigned study of stroke in Iran and Middle East. Based on this standard epidemiologic study; The crude annual incidence rate of First Ever Stroke (FES) is 139 (95% CI, 128 to 149) per 100 000; for men, 144 (95% CI, 128 to 159), and for women, 133 (95% CI, 118 to 148). The incidence rates increases significantly with each decade of life and is similar in men and women. Subtypes of FES in 81.9% of patients is ischemic stroke,12.7% is intracerebral hemorrhage, and 2.4% have subarachnoid hemorrhage. The crude annual incidence rate per 100 000 inhabitants is 113 (95% CI, 104 to 123) for ischemic stroke, 18 (95% CI, 14 to 21) for intracerebral hemorrhage and 3 (95% CI, 2 to 5) for subarachnoid hemorrhage. Ischemic strokes are occurring approximately 1 decade earlier in Iran than in other countries.
Strategic Analysis of Shiraz Medical Tourism Industry: A Mixed Method Study
Authors: Rahimi Zarchi Mohammad Kazem , Jabbari Alireza , Hatam Nahid , Bastani Peivand , Shafaghat Tahereh , Fazelzadeh Omid 
Published: January 2022

Background: The connection between healthcare and tourism industries in many countries has created one of the largest service industries, i.e. "medical tourism industry". Medical tourism services bring significant benefits to the countries. This study aimed to examine internal and external factors affecting Shiraz medical tourism industry as well as the potential capabilities of the industry.Materials and Methods: This applied research is a mixed method study using both qualitative and quantitative methods in 2017. The study population consisted of all organizations involved in the medical tourism industry. In this study, the deductive qualitative content analysis was employed to determine the internal and external factors affecting Shiraz medical tourism industry. Furthermore, the SWOT technique was used to analyze the data obtained from individual interviews and meetings with expert panels. Results: Internal and external factors were classified into 4 main themes (namely strengths, weaknesses, opportunities and threats) and 10 sub-themes, of which five cases (FORMM) were related to internal factors (i.e. finance, production and products (operations), research and development, marketing and management) and five cases (STEPC) were associated with external factors including socio-cultural, technology, economy, political and competitive ones. Also, the matrix of the internal and external factors indicated an offensive zone for this industry. Conclusions: This industry can make use of the strengths and opportunities to confront the threats and negative points through identifying internal and external factors in order to enjoy benefits such as job creation and revenue gains. [GMJ.2018;7:e1021]
Quantitation of Colonic Cells as Severity Markers in Patients with Irritable Bowel Syndrome
Authors: Miri Mohammad Bagher , Sadeghi Amir , Moradi Afshin , Rostami-Nejad Mohammad , Ehsani-Ardekani Mohammad-Javad , Asadzadeh-Aghdaei Hamid , Safari Mohammad-Taghi , Zali Mohammad Reza 
Published: January 2022

Background: Irritable bowel syndrome (IBS) is the most common gastrointestinal syndrome. Routine histopathology and immunohistochemistry (IHC) evaluations have shown an increase in the number of different inflammatory cells in the colon of IBS patients. In this study, we have compared the number of intraepithelial lymphocytes (IELs), eosinophils, mast cells and CD3+ T cells, in IBS patients and normal subjects. Materials and Methods: In 2016, seventy-nine patients with IBS and seventy-nine healthy subjects who underwent colonoscopy for other non-specific causes and with no pathologic findings, were enrolled in this cross-sectional study. Biopsy specimens obtained from the colon were stained, using IHC methods to determine the number of IELs, eosinophils, mast cells and CD3+ T cells. Quantitative and qualitative variables were compared between the two groups, using a Chi-square test and Student’s t-test. Results: Seventy-nine patients with IBS, 79.7% females with a mean age of 42.5±14.6 years, were recruited, as the case group, and seventy-nine individuals, 51.9% females with a mean age of 39.7±18.9 years, were enrolled as controls. The average number of IELs per high power fields (hpf) was found to be higher in the IBS group, and this difference was statistically significant (32.8±11.8 vs. 28.6±12.9; P=0.034). Also, the mean count/hpf of CD3+ T lymphocytes (23.1±7.9 vs. 20.2±8.1; P=0.024) and mast cells (7.6±3.1 vs. 6.6±3.0; P=0.041) were significantly higher in the IBS group, compared to the control group. The number of eosinophils was higher in the IBS group, but the differences were not statistically significant (P=0.066). Conclusion: According to the results, we suggest that analysis of immune cells and IELs in intestinal biopsies might be an appropriate method for diagnosis of IBS. [GMJ.2018;7:e1063]