bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate change implications for olive flowering in Crete, Greece: projections based on historical data
Authors: Grillakis Manolis G. , Kapetanakis Evangelos G. , Goumenaki Eleni 
Published: November 2022

AbstractClimate change is expected to pose major challenges for olive cultivation in many Mediterranean countries. Predicting the development phases of olive trees is important for agronomic management purposes to foresee future climate impact and proactively act toward adaptation and mitigation strategies. In this study, a statistical model was developed based on winter chill accumulation and, in sequence, on heat accumulation to assess the changes in flowering occurrence for Olea europaea cv. Koroneiki, in the island of Crete, Greece. The model was based on and calibrated with long-term phenological observations and temperature data from four different sites in the island, spanning an elevation gradient between 45 and 624 m a.s.l. This model was used to assess the changes in flowering emergence under two Representative Concentration Pathway scenarios, RCP4.5 and RCP8.5, as projected by seven high-resolution Euro-CORDEX Regional Climate Models. Changes in chill accumulation were determined using the Dynamic Model. Reduction rates in chill accumulation for the whole chilling season ranged between 12.0 and 28.3% for the near future (2021–2060) and 22.7 and 70.9% for the far future (2061–2100), in comparison to the reference period of 1979–2019. Flowering was estimated to occur between 6 and 10 days earlier in the near future and between 12 and 26 days earlier in the far future, depending on the elevation and the climate change scenario.
Workflow analysis of data science code in public GitHub repositories
Authors: Ramasamy Dhivyabharathi , Sarasua Cristina , Bacchelli Alberto , Bernstein Abraham 
Published: November 2022

AbstractDespite the ubiquity of data science, we are far from rigorously understanding how coding in data science is performed. Even though the scientific literature has hinted at the iterative and explorative nature of data science coding, we need further empirical evidence to understand this practice and its workflows in detail. Such understanding is critical to recognise the needs of data scientists and, for instance, inform tooling support. To obtain a deeper understanding of the iterative and explorative nature of data science coding, we analysed 470 Jupyter notebooks publicly available in GitHub repositories. We focused on the extent to which data scientists transition between different types of data science activities, or steps (such as data preprocessing and modelling), as well as the frequency and co-occurrence of such transitions. For our analysis, we developed a dataset with the help of five data science experts, who manually annotated the data science steps for each code cell within the aforementioned 470 notebooks. Using the first-order Markov chain model, we extracted the transitions and analysed the transition probabilities between the different steps. In addition to providing deeper insights into the implementation practices of data science coding, our results provide evidence that the steps in a data science workflow are indeed iterative and reveal specific patterns. We also evaluated the use of the annotated dataset to train machine-learning classifiers to predict the data science step(s) of a given code cell. We investigate the representativeness of the classification by comparing the workflow analysis applied to (a) the predicted data set and (b) the data set labelled by experts, finding an F1-score of about 71% for the 10-class data science step prediction problem.
Device-based percutaneous treatments to decompress the left atrium in heart failure with preserved ejection fraction
Authors: Riccardi Mauro , Tomasoni Daniela , Vizzardi Enrico , Metra Marco , Adamo Marianna 
Published: November 2022

AbstractHeart failure with preserved ejection fraction (HFpEF) accounts for more than half of heart failure hospital admissions in the last years and is burdened by high mortality and poor quality of life. Providing effective management for HFpEF patients is a major unmet clinical need. Increase in left atrial pressure is the key determinant of pulmonary congestion, with consequent dyspnoea and exercise limitation. Evidence on benefits of medical treatment in HFpEF patients is limited. Thus, alternative strategies, including devices able to reduce left atrial pressure, through an interatrial communication determining a left–right shunt, were developed. This review aims to summarize evidence regarding the use of percutaneous interatrial shunting devices. These devices are safe and effective in improving hemodynamic and clinical parameters, including pulmonary capillary wedge pressure, 6-min walking distance, and New York Heart Association functional class. Data on cardiovascular mortality and re-hospitalization for heart failure are still scarce.
Taxonomic and functional structure of macrobenthic invertebrate communities and their response to environmental variables along the subbranches of the Nile River (rayahs), Egypt
Authors: Bendary Reda E. , Ibrahim Shaimaa M. , Goher Mohamed E. , Elsaied Hosam E. , El Shabrawy Gamal M. , El Mordy Mohamed Abd , Khalil Magdy T. 
Published: November 2022

Abstract
Macrobenthic invertebrate communities serve as markers of anthropogenic stress in freshwater ecosystems. In this study, 17 sampling sites were selected from two Nile river subbranches (El-Rayah El-Behery and El-Rayah El-Nassery) and subjected to different anthropogenic influences to explore the ecological environment and characteristics of macrobenthos communities. Macrobenthos were studied using taxonomic diversity and biological trait analysis to investigate how human activity and variation in water quality affect their structure and function. A total of 37 taxa represented by 43,389 individuals were recognized. The communities are composed chiefly of Oligochaeta and aquatic insects. Multivariate statistical analyses found that the most influential environmental variables in the structural and functional community were sodium, dissolved oxygen, silicate, pH, calcium, and cadmium. At high levels of pollution, notably sewage and industrial pollution in the northern part of El-Rayah El-Behery, characteristics such as larger body size, detritus feeders, burrowers, and high tolerance to pollution predominated, whereas at low levels of pollution, features such as small body sizes, scraper and predator feeders, intolerant and fairly tolerant of pollution, and climber and swimmer mobility are predominant. The results confirm our prediction that the distribution of macroinvertebrate traits varies spatially in response to environmental changes. The diversity-based method distinguished impacted sewage and industrial sites from thermal effluent sites, while the trait-based approach illustrated an apparent variance between the ecological status of contaminated regions. Therefore, the biological features should be employed in addition to structural aspects for assessing the biodiversity of macroinvertebrate communities under environmental stressors.
Attitudes Towards Rape and Their Determinants Among Men, Women and Non-Binary People in Poland
Authors: Olszewska Klaudia , Piotrowski Przemysław , Wojciechowski Bartosz W. 
Published: November 2022

AbstractThe aim of this paper is to present the results of research on attitudes towards rape conducted in a group of 850 adult Poles, including 505 women, 310 men and 35 non-binary people, and to analyze their selected correlates: rape myth acceptance, right-wing authoritarianism and rape empathy. Non-binary people have only recently been included in research as a distinct group and little information can be found in the literature on the characteristics of their attitudes towards social problems. Therefore particular attention was paid to comparing the attitudes towards rape of non-binary people with those of women and men. In analyzing the results, the authors took into account the current socio-political situation in Poland. The results indicate that attitudes toward sexual aggression are related to the type of gender identification. The most positive attitudes towards rape victims among the groups participating in the research are held by non-binary people. Furthermore, attitudes towards rape are determined by rape myths, right-wing authoritarianism and empathy for victims of rape.
Mastectomy with one-stage or two-stage reconstruction in breast cancer: analysis of early outcomes and patient’s satisfaction
Authors: Gurrado Angela , Pasculli Alessandro , Toma Alessia , Maruccia Michele , Elia Rossella , Moschetta Marco , Telegrafo Michele , De Luca Giuseppe Massimiliano , Lavermicocca Walter , Poli Elisabetta , Prete Francesco Paolo , Sgaramella Lucia Ilaria , Giudice Giuseppe , Testini Mario 
Published: November 2022

AbstractAim of this study is to compare early post-operative outcomes and patient’s satisfaction after skin-sparing and/or nipple-sparing mastectomy (SSM/SNSM) followed either by breast reconstruction with one-stage prepectoral implantation or two-stage technique for breast cancer (BC) or BRCA1/2 mutation.From January 2018 to December 2021, 96 patients (mean age of 51.12 ± 10.9) underwent SSM/SNSM and were divided into two groups: in group A (65 patients, 67.7%), mastectomy was followed by one-stage reconstruction; in group B (31 patients, 32.3%) by two-stage. Operative time was significantly longer in A vs. B (307.6 ± 95.7 vs. 254.4 ± 90.91; P < 0.05). Previous breast surgery was more common in B vs. A (29.0% vs. 7.7%; P < 0.05), while bilateral surgery was performed more frequently in A vs. B (40% vs. 6.5%; P = 0.001). All SSM/SNSM for BRCA1/2 mutation were followed by immediate prepectoral implantation. No significant differences were found between groups in terms of post-operative complications. At pathology, DCIS and invasive ST forms, such as multicentric/multifocal forms, were detected more frequently in B, while NST type in A (all P < 0.05). A multivariate analysis showed improved post-operative satisfaction at BREAST-Q survey in Group A (P = 0.001). Encouraging oncologic outcomes after SSM/SNSM for BC enabled the improvement of breast reconstructive techniques. One-stage reconstruction is characterized by better aesthetic outcomes and by greater patient’s satisfaction. When SSM/SNSM is technically difficult to perform, as in multicentric/multifocal forms or previous breast surgery, mastectomy followed by two-stage reconstruction should be considered to achieve a radical surgery.
Finite convergence of extragradient-type methods for solving variational inequalities under weak sharp condition
Authors: Trinh Thanh Quoc , Vinh Le Van , Vuong Phan Tu 
Published: November 2022

AbstractWe prove the finite convergence of the sequences generated by some extragradient-type methods solving variational inequalities under the weakly sharp condition of the solution set. In addition, we provide estimations for the number of iterations to guarantee the sequence converges to a point in the solution set and prove that these estimations are optimal. Numerical examples are presented to illustrate the theoretical results.
Serre duality for tame Deligne–Mumford stacks
Authors: Levchenko Denis 
Published: November 2022

AbstractUsing the exceptional inverse image functor for quasi-finite proper morphisms of separated tame Deligne–Mumford stacks of finite type over a fieldk, Serre duality is obtained in varying degrees of generality for tame Deligne–Mumford stacks. The approach follows that for schemes.
Continuous Quantity and Quality Modeling for Assessing the Effect of SUDS: Application on a Conceptual Urban Drainage Basin
Authors: Ferrans Pascual , Temprano Javier 
Published: November 2022

Abstract
The development of computational tools based on urban drainage models is fundamental for the correct selection of SUDS. The present study proposes a systematic approach based on continuous modeling on USEPA SWMM. The objective was to select the most suitable Sustainable Urban Drainage Systems (SUDS) by evaluating several aspects related to their design and configuration. The proposed methodology was applied to a conceptual watershed with meteorological information from Santander, Spain. The analysis of SUDS design parameters showed that only the surface variables showed a sensitivity of ≈20% for berm height and vegetation volume. The optimal configuration for the case study was a SUDS train consisting of green roofs, permeable pavements, vegetated swales and rain gardens, with 1% of the total subcatchment area cover, one structure, and a semi-aggregated spatial distribution. The methodology proved efficient but also highly dependent on the case study parameters and the meteorological conditions. The SUDS proved to have different efficiencies (30%—90%) in reducing the total runoff volume, the peak flow, and the pollutant loads depending on the region where the conceptual watershed was modeled. The methodology proved to be efficient for studying the combinations and interconnection of seven different typologies, as well as the effect of SUDS configuration, design and distribution on their performance.
KM-408, a novel phenoxyalkyl derivative as a potential anticonvulsant and analgesic compound for the treatment of neuropathic pain
Authors: Waszkielewicz Anna , Marona Henryk , Pańczyk-Straszak Katarzyna , Filipek Barbara , Rapacz Anna , Sałat Kinga , Kubacka Monika , Cios Agnieszka , Fedak Filip , Walczak Maria , Hubicka Urszula , Kwiecień Anna , Żuromska-Witek Barbara , Szafrański Przemysław W. , Koczurkiewicz-Adamczyk Paulina , Pękala Elżbieta , Przejczowska-Pomierny Katarzyna , Pociecha Krzysztof , Wyska Elżbieta 
Published: November 2022

AbstractBackgroundEpilepsy frequently coexists with neuropathic pain. Our approach is based on the search for active compounds with multitarget profiles beneficial in terms of potential side effects and on the implementation of screening for potential multidirectional central activity.MethodsCompounds were synthesized by means of chemical synthesis. After antiseizure and neurotoxicity screening in vivo,KM-408and its enantiomers were chosen for analgesic activity evaluations. Further safety studies included acute toxicity in mice, the effect on normal electrocardiogram and on blood pressure in rats, whole body plethysmography in rats, and in vitro and biochemical assays. Pharmacokinetics has been studied in rats afterivandpoadministration. Metabolism has been studied in vivo in rat serum and urine. Radioligand binding studies were performed as part of the mechanism of action investigation.ResultsSelected results forKM-408: Kisigma = 7.2*10–8; Ki5-HT1A = 8.0*10–7; ED50MES (mice,ip) = 13.3 mg/kg; formalin test (I phase, mice,ip)—active at 30 mg/kg; SNL (rats,ip)—active at 6 mg/kg; STZ-induced pain (mice,ip)—active at 1 mg/kg (von Frey) and 10 mg/kg (hot plate); hot plate test (mice,ip)—active at 30 mg/kg; ED50capsaicin test (mice,ip) = 18.99 mg/kg; tail immersion test (mice)—active at 0.5%; corneal anesthesia (guinea pigs)—active at 0.125%; infiltration anesthesia (guinea pigs)—active at 0.125%.ConclusionsWithin the presented study a novel compound,R,S-2-((2-(2-chloro-6-methylphenoxy)ethyl)amino)butan-1-ol hydrochloride (KM-408) with dual antiseizure and analgesic activity has been developed for potential use in neuropathic pain treatment.Graphical abstract
Theoretical and experimental analysis of guided wave propagation in plate-like structures with sinusoidal thickness variations
Authors: Zima Beata , Moll Jochen 
Published: November 2022

Abstract
Guided waves have attracted significant attention for non-destructive testing (NDT) and structural health monitoring (SHM) due to their ability to travel relatively long distances without significant energy loss combined with their sensitivity to even small defects. Therefore, they are commonly used in damage detection and localization applications. The main idea of incorporating guided waves in NDT and SHM is based on processing the received signals and appropriate interpretation of their characteristics. A great amount of research devoted to diagnostics of plate-like structures considers specimens with constant thickness, which significantly facilities the diagnostic process. In such a case the velocity is also assumed to be constant. However, the developed diagnostic methods should be applicable, especially for the structures exposed to an aggressive environment, excessive load, or unfavorable weather conditions, etc., when the probability of damage occurring is much higher. In such cases, the assumption about the uniform thickness alongside the propagation path cannot be applied in every case. Thus, the present study is focused on wave propagation in metallic plates with variable thickness. The results of theoretical, numerical and experimental investigations of antisymmetric Lamb mode propagation in aluminum plates with a sine-shaped surface are presented. In the first step, the influence of non-uniform thickness distribution on wave velocity has been described. Next, the inverse problem aimed at shape reconstruction based on time of flight (ToF) analysis and spatially varying wave velocity was solved and compared with the standard dispersion curve-fitting method.
Effectiveness of Different Feeding Techniques for Post-stroke Dysphagia: An Updated Systematic Review and Meta-analysis
Authors: Wang Shaowei , Zeng Xi , Zhang Qiongshuai , Li Heping 
Published: November 2022

Abstract
Purpose
With the improvement of people’s life expectancy, the incidence of stroke is high in the world. Post-stroke Dysphagia seriously affects people’s quality of life, among which malnutrition and pulmonary infection are the most common complications of post-stroke Dysphagia. At this point, it is very important to choose the right enteral and parenteral feeding mode. Current nutrition methods commonly used in patients with dysphagia after stroke include Intermittent oral to esophageal tube feeding (IOE), Nasogastric tube (NG), Nasal Jejunal feeding tubes (NJ), Percutaneous endoscopic gastrostomy (PEG).The purpose of this meta-analysis was to study the prognosis of patients with dysphagia after stroke who chose different nutritional methods.

Methods
We conducted a systematic review and meta-analysis of randomized controlled trials (RCTS) to examine the effects of different nutritional modalities on outcomes in patients with post-stroke dysphagia. We searched the Cochrane Library, PubMed, Medline, China National Knowledge Infrastructure (CNKI), Wanfang, and the VIP database. The search period is from the library's establishment to December 31, 2021.At least 2 reviewers independently assessed eligibility criteria, extracted data, and assessed the risk of bias. Standardized mean difference (SMD), relative risk (RR), and odds ratio (OR) were calculated using a random-effects model.

Results
Fourteen studies were identified across six databases that met the inclusion criteria, The results of meta-analysis showed that Intermittent oral to esophageal tube feeding (IOE) could improve the nutritional levels of patients better than nasogastric tube (NG) (MD 1.95, 95%CI 1.22–2.67, P < 0.00001, I2 = 0%), and reduced the incidence of aspiration pneumonia (RR 0.39, 95%CI 0.23–0.66, P = 0.0004, I2 = 0%), improved swallowing function (OR 3.92, 95%CI 2.15–7.14, P < 0.00001, I2 = 0%). Although Percutaneous endoscopic gastrostomy (PEG) can improve the nutrition of patients in the short term, the long-term prognosis remains to be discussed. In addition, the Nasal Jejunal feeding tubes (NJ) significantly reduced the incidence of post-stroke pneumonia compared with NG (RR 0.51, 95%CI 0.29–0.92, P = 0.03, I2 = 0%).

Conclusions
According to the results of meta-analysis, IOE can better improve the nutritional level of patients and reduce the incidence of complications. However, due to the lack of popularity and small target clients, patients who do not accept IOE enteral feeding for various reasons and choose nasal feeding can consider using NJ as a long-term enteral feeding method, and guard against adverse events when performing supplementary nutrition.
Inferring Advective Timescales and Overturning Pathways of the Deep Western Boundary Current in the North Atlantic Through Labrador Sea Water Advection
Authors: Chomiak Leah N. , Yashayaev Igor , Volkov Denis L. , Schmid Claudia , Hooper James A. 
Published: November 2022

AbstractThe Subpolar North Atlantic plays a critical role in the formation of the deep water masses which drive Atlantic Meridional Overturning Circulation (AMOC). Labrador Sea Water (LSW) is formed in the Labrador Sea and exported predominantly via the Deep Western Boundary Current (DWBC). The DWBC is an essential component of the AMOC advecting deep waters southward, flowing at depth along the continental slope of the western Atlantic. By combining sustained hydrographic observations from the Labrador Sea to 26.5°N, we investigate the signal propagation and advective timescales of LSW via the DWBC from its source region to the Tropical Atlantic through various approaches using robust neutral density classifications. Two individually defined LSW classes are observed to advect on timescales that support a new plausible hydrographically observed advective pathway. We find each LSW class to advect on independent timescales, and validate a hypothesized alternative‐interior advection pathway branching from the DWBC by observing the arrival of LSW outside of the DWBC in the Bermuda basin on timescales similar to arriving at 26.5°N, 10–15 yr after leaving the source region. Advective timescales estimated herein indicate that this interior pathway is likely the main advective pathway; it remains uncertain whether a direct pathway plays a significant advective role. Using LSW convective signals as advective tracers along the DWBC permits the estimation of advective timescales from the subpolar to tropical latitudes, illuminating deep water advection pathways across the North Atlantic and the lower‐limb of AMOC as a whole.
On Constructing a Realistic Truth Model Using Ionosonde Data for Observation System Simulation Experiments
Authors: Hughes Joseph , Forsythe Victoriya , Blay Ryan , Azeem Irfan , Crowley Geoff , Wilson Walter “Junk” , Dao Eugene , Colman Jonah , Parris Richard 
Published: November 2022

AbstractThe ionosphere contains many small‐scale electron density variations that are under represented in smooth physics‐based or climatological models. This can negatively impact the results of Observation System Simulation Experiments, which use a truth model to simulate data. This paper addresses this problem by using ionosonde data to study ionospheric variability and build a new truth model with empirically driven variations. The variations are studied for their amplitude, horizontal and vertical size, and temporal extent. Results are presented for different local times, seasons, and at solar minimum and solar maximum. We find that these departures from a smooth background are often as large as 25% and are most prevalent near 250 km in altitude. They have horizontal spatial extents that vary from a few hundred to a few thousand kilometers, and typically have the largest horizontal extent at high altitudes. Their vertical extents follow the same pattern of being larger at high altitudes, but they only vary from 10s of km up to 200 km in vertical size. Temporally, these variations can last for a few hours. A procedure for using these spatial and temporal distributions to add empirically driven variance to a smooth truth model is outlined. This process is used to make a truth model with representative variations, which is compared to ionosonde data as well as Global Positioning System Total Electron Content data that was not used to inform the model. The new model resembles the data much better than the smooth models traditionally used.