bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality intrapartum care expectations and experiences of women in sub- Saharan African Low and Low Middle-Income Countries: A qualitative meta- synthesis
Authors: Ahmed Salma A.E. , Mahimbo Abela , Dawson Angela 
Published: September 2022

Abstract
Background:
Women-centred maternity care is respectful and responsive to women’s needs, values, and preferences. Women’s views and expectations regarding the quality of health services during pregnancy and childbirth vary across settings. Despite the need for context-relevant evidence, to our knowledge, no reviews focus on what women in sub-Saharan African Low and Low Middle-Income Countries (LLMICs) regard as quality intrapartum care that can inform quality guidelines in countries.
Methods:
We undertook a qualitative meta-synthesis using a two-stage thematic synthesis to identify the experiences and expectations of women in sub-Saharan African LLMICs with quality intrapartum care. Following a priori protocol, we searched eight databases for primary articles using keywords. We used Covidence to collate citations, remove duplicates, and screen articles using a priori set inclusion and exclusion criteria. Two authors independently screened first the title and abstracts, and the full texts of the papers. Using a data extraction excel sheet, we extracted first-order constructs and second-order relevant to review objectives. The WHO framework for a positive childbirth experience underpinned data analysis.
Results
Of the 7197 identified citations, 30 articles were included in this review. Women’s needs during the intrapartum period resonate with what women want globally, however, priorities regarding the components of quality care for women and the urgency to intervene differed in this context given the socio-cultural norms and available resources. Women received sub-quality intrapartum care and global standards for women-centred care were often compromised. They were mistreated verbally and physically. Women experienced poor communication with their care providers and non-consensual care and were rarely involved in decisions concerning their care. Women were denied the companion of choice due to cultural and structural factors.
Conclusion
To improve care seeking and satisfaction with health services, women-centred care is necessary for a positive childbirth experience. Women must be meaningfully engaged in the design of health services, accountability frameworks, and evaluation of maternal services. Research is needed to set minimum indicators for women-centred outcomes for low-resource settings along with actionable strategies to enhance the quality of maternity care based on women’s needs and preferences.
Post-transplant cyclophosphamide versus antithymocyte globulin as GVHD prophylaxis for 10/10 HLA-matched unrelated allogeneic hematopoietic stem cell transplantation.
Authors: Dachy Francois , Fürst Sabine , Calmels Boris , Pagliardini Thomas , Harbi Samia , Bouchacourt Benjamin , Calleja Anne , Lemarie Claude , Collignon Aude , Morel Guillaume , Legrand Faezeh , Bekrieva Elena , granata angela , Weiller Pierre-Jean , CHABANNON Christian , de Colella Jean-Marc Schiano , Vey Norbert , Blaise Didier , Devillier Raynier 
Published: September 2022

Abstract
After T-cell replete haploidentical stem cell transplantation, GVHD prophylaxis with post-transplant cyclophosphamide (PT-Cy) is now evaluated in unrelated donor (UD) transplants, where antithymocyte globulin (ATG) remains standard. We report the outcome of patients transplanted from HLA-10/10 matched unrelated donor (MUD) treated with PT-Cy (n=30), in comparison with a historical cohort treated with ATG (n=64).
In the PT-Cy group, we observed lower 2-4 acute GVHD (23% vs. 45%, p=0.014), lower chronic GVHD (all grades: 13% vs 33%, p=0.029; moderate to severe: 10% vs. 27%, p=0.039) but no difference in the relapse (20% vs. 11%, p=0.628), non-relapse mortality (3% vs 11%, p=0.169), progression free survival (77% vs 78%, p=0.638) and overall survival (87% vs 83%, p=0.602). Neutrophil (19 vs 17 days, p=0.049) and platelet (26 vs 10 days, p<0.001) recovery was significantly delayed in the PT-Cy group.
Then, we followed the GVHD and the immunosuppressive treatments (IST) prevalence in disease free patients as marker of quality of life. At 6 months, 5% and 36% in the PT-Cy group were living with GVHD and IST, versus 26% (p=0.030) and 64% (p=0.049).
We conclude that PT-Cy is an effective GVHD prophylaxis in 10/10-HLA MUD allo-SCT, representing a valuable alternative to ATG.
Spectroscopic discrimination of Persian Gulf alga species using chemometrics approaches: A Comparative study using data fusion
Authors: Tarighat Maryam Abbasi , Abdi Gholamreza , Tussi Fatemeh 
Published: September 2022

Abstract
In the present study, multivariate chemometric techniques have been employed for discrimination of Persian Gulf seaweeds according to their species and area using FTIR and UV-Vis spectra. Based on the findings, this work could be differentiated diversity of algae species without time consuming sample preparation steps, measuring cell content and large consumption of material for analysis. The principal component analysis (PCA), PCA- discriminant analysis (PCA-LDA), and PLS-DA (partial least squares-discriminant analysis) were employed for clustering of samples. Based on our knowledge, the current work is the first study that examined the concatenation of SOMs clusters of different techniques for the classification of algae samples. Comparison of results showed that the classification parameters obtained by SOMs- fusion approach is better than other models and 100% prediction accuracy was achieved. The data sets were pretreated with autoscaling and Savitzky-Golay smoothing for elimination of the noise and background interferences and improving the accuracy of classification. Also, the Kohonen self-organization map (SOMs) was considered for reducing the dimension of spectroscopic data. The fusion matrix was created by a combination of best SOMs clusters of FTIR and UV-Vis spectra. The models are capable to distinguish the similarity between the face mask contain spirulina with spirulina alone.
Adaptive event-triggered control for Markov jump systems under hybrid cyber-attacks and its application
Authors: Ali M Syed , M Mubeen Tajudeen , Rajchakit Grienggrai , Jirawattanapanit Anuwat 
Published: September 2022

Abstract
This article investigates event-triggered control (ETC) of discrete-time Markov jump systems (MJSs) subject to hybrid cyber-attacks and unmeasured states. To reduce data transmission load, a mode-dependent event-triggered mechanism (ETM) has been developed. The unmeasured states are estimated using a Luenberger observer. Here deception attacks and DoS attacks are addressed. It is anticipated that input control signals sent across a network are vulnerable to cyber-attacks, in which adversaries could inject fake data into the control signals. So to secure the closed-loop system, sufficient conditions are derived. The solution of set matrix inequalities is used to build observer and controller gains. Finally, inverted pendulum applications are presented to illustrate the effectiveness and feasibility of the obtained theoretical results.
Dietary resveratrol intervention improves lipid homeostasis via attenuating HFD-induced fecal chenodeoxycholic acid and jejunum SR-B1 elevation
Authors: Pang Juan , Raka Fitore , Heirali Alya Abbas , Shao Weijuan , Liu Dinghui , Gu Jianqiu , Feng Jia Nuo , Mineo Chieko , Shaul Philip , Qian Xiaoxian , Coburn Bryan , Adeli Khosrow , Ling Wenhua , Jin Tianru 
Published: September 2022

Abstract
Two common features of dietary polyphenols have hampered our mechanistic understanding of their metabolic beneficial effects for decades: targeting multiple organs and extremely low bioavailability. We show here that resveratrol intervention (REV-I) in high fat diet (HFD)-challenged mice inhibited chylomicron secretion, associated with reduced jejunal but not hepatic SR-B1 expression. Intestinal-mucosa-specific SR-B1-/- mice on HFD challenge exhibited improved lipid homeostasis but showed virtually no further response to REV-I. The SR-B1 inhibitor BLT-1 and REV-I generated no additive effect on improving lipid homeostasis. SR-B1 expression in the Caco-2 cell line cannot be repressed by pure resveratrol while fecal-microbiota transplantation from mice on REV-I suppressed jejunal SR-B1 in recipient mice. REV-I reduced fecal levels of bile acids including chenodeoxycholic acid (CDCA), while CDCA stimulated FXR, NF-κB and SR-B1 in Caco-2 cells. We conclude that gut microbiome is the primary target of REV-I, and REV-I improves lipid homeostasis at least partially via attenuating CDCA-stimulated gut SR-B1 elevation.
Computational Correlation analysis of In-doped Aluminium Antimonide Alloy for Optoelectronic Applications: A First Principle Study
Authors: Nabi Shafqat , Anwar Abdul Waheed , Ahmad Muhammad , Haq Najam Ul , Waqas Rana , Tayyab Muhammad , Moin Muhammad , Ali Anwar , Afzal Muhammad , Nabi Kashif 
Published: September 2022

Abstract
The first Principle calculations are made to study the structural electronic and optical properties for indium doped aluminum antimonide. The most appropriate method of density functional theory (DFT) naming Full Potential Linearized Augmented Plane Wave (FP-LAPW) is used. The structural properties like Lattice constant (a), pressure derivative, bulk modulus (B) examined by Local density approximation (LDA) along with generalized gradient approximation (GGA). Generalized gradient approximation along with TB-mBJ is used to determine electronic parameters like band structure along and density of states. According to the computed results the binary compound AlSb is optically inactive and exhibits an indirect (Γ -X) band gap. By increasing the concentration of indium with different percentages, the indirect band gape shifted to direct (Γ – Γ) band gap which shows material is optically active. The optical properties of material including dielectric (Real and imaginary part) constant, reflectivity, refractive index, energy loss, absorption coefficient, and optical conductivity have changed significantly. Electronic and optical properties are modified by (TB-mBJ) approach. The results obtained are examined with experimental data and utilized as a starting point to propose that the material is the superlative choice for optoelectronic devices/applications.
Accounting for G×E interactions in plant breeding: a probabilistic approach
Authors: Bijari Reyhaneh , Olafsson Sigurdur 
Published: September 2022

Abstract
In plant breeding trials the mean phenotypic responses of two experimental genotypes are often close; and which genotype appears to perform better depends on the specific environments that are observed. When only one of the genotypes must be selected, the conclusion drawn by comparing means across any set of observed environments may differ from the conclusion that would be drawn if all target environments could have been observed, in which case the wrong selection may be made. This paper proposes a new method of comparing genotypes that aims to select the genotype that is more likely to perform better across a set of environments, rather than the one that has the better mean. The implementation uses bootstrap resampling to estimate the probability that one genotype outperforms another in a set of observed environments, and by doing so accounts for the uncertainty caused by observing limited environments. The results show that due to the different genetic-by-environment (G×E) interaction effects, the genotype that is more likely to be better is sometimes different than the one with the better mean and the probabilistic comparison accounts for both the mean and the interaction effects.
The anti-inflammatory effect of dimethyl trisulfide in experimental acute pancreatitis
Authors: Orján Erik Márk , Kormányos Eszter Sára , Fűr Gabriella Mihalekné , Dombi Ágnes , Bálint Emese Réka , Balla Zsolt , Balog Beáta Adél , Dágó Ágnes , Totonji Ahmad , Bátai Zoárd István , Pozsgai Gábor , Pintér Erika , Rakonczay Zoltán , Kiss Lóránd 
Published: September 2022

Abstract
Several organosulfur compounds, such as dimethyl trisulfide (DMTS), exhibit anti-inflammatory properties. Our aims were to investigate the effects of DMTS on acute pancreatitis (AP) and its mechanism of action in both in vivo and in vitro studies. AP was induced in FVB/n mice or Wistar rats by caerulein or L-ornithine-HCl, respectively. DMTS treatments were applied subcutaneously. AP severity was evaluated with histological scoring of the pancreas, pancreatic water content and myeloperoxidase activity measurements. The behaviour of animals were followed. Western blot was performed to determine the extent of pancreatic heat shock protein 72 (HSP72) expression. In vitro acinar viability, reactive oxygen species (ROS) production, and intracellular Ca2+ concentrations were determined in isolated pancreatic acinar cells. DMTS dose dependently reduced the severity of AP. It decreased the pancreatic infiltration of leukocytes, myeloperoxidase activity and cellular damage in mice, but it was less effective in rats. During AP, DMTS upregulated the HSP72 expression. DMTS showed cytoprotection against H2O2 and AP inducing agents, it reduced the level of ROS, and altered the caerulein-evoked Ca2+ signals. Overall, DMTS significantly ameliorated the severity of AP and protected pancreatic acinar cells. Our results suggest that DMTS have anti-inflammatory effects, so organosulfur compounds are worth further investigation in this potentially lethal disease.
A balanced omega-6/omega-3 polyunsaturated fatty acid diet suffices to prevent autism spectrum disorder symptoms in an environmental mouse model
Authors: Jaber Mohamed , Turpin Valentine , Schaffhauser Maud , Thabault Mathieu , Aubert Agnes , Joffre Corinne , Balado Eric , Longueville Jean-Emmanuel , Francheteau Maureen , Burucoa Christophe , Pichon Maxime , Laye Sophie 
Published: September 2022

Abstract
Exploration of potential nutritional therapies in autism spectrum disorder (ASD), notably through omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation, have been explored but remain elusive as to their specific contribution to the phenotype and their potential in ameliorating cardinal symptoms of the disease. Here, we compared the effects of two diets that differ in their n-3 PUFA species on ASD symptoms in the valproic acid (VPA) mouse model. For this, pregnant C57BL/6J females were i.p. injected with VPA at embryonic day 12.5 (E12.5; 450mg/kg) and fed with either a balanced diet (n-3 bal) with alpha-linolenic acid (ALA) as the only n-3 PUFA source or a n-3 long-chain PUFA (LCPUFA) supplemented diet (n-3 supp) with docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) as the major n-3 PUFA species. Diets were provided starting E0, throughout lactation and on to the offspring after weaning through adulthood. Maternal and pup behaviors were investigated followed by social, motor and gait behavior in young adult offspring. Post-mortem investigations included cerebellar Purkinje cell (PC) count, liver and cerebellar fatty acid (FA) composition, inflammation markers’ levels and microbiota composition. All experiments were performed separately on male and female offspring. Developmental milestones were delayed in the n-3 LCPUFA groups, whatever the treatment. VPA-exposed offspring did not show social deficits, stereotypies, or PC loss. Global activity and gait were altered by diet and treatment with sex differences. TNF-alpha cerebellar levels were slightly increased by n-3 LCPUFA supplementation, only in females. With both diets, VPA did not alter microbiota composition in male and female offspring nor cerebellar n-3 LCPUFA levels, except in females. Our results indicate that a balanced n-3/n-6 PUFA diet may suffice to protect from ASD symptoms and physiopathology, and that n-3 LCPUFA supplementation brings limited benefits in the VPA mouse model.
Thermostability improvement of sucrose isomerase PalI NX-5: a comprehensive strategy
Authors: Sardiña-Peña Amado Javier , Ballinas-Casarrubias Lourdes , Siqueiros-Cendón Tania Samanta , Espinoza-Sánchez Edward Alexander , Flores-Holguín Norma Rosario , Iglesias-Figueroa Blanca Flor , Rascon-Cruz Quintin 
Published: September 2022

Abstract
Objective: To increase the thermal stability of sucrose isomerase from Erwinia rhapontici NX-5, we designed a comprehensive strategy that combines different thermostabilizing elements.
Results: We identified 19 high B value amino acid residues for site-directed mutagenesis. An in silicoevaluation of the influence of post-translational modifications on the thermostability was also carried out. The sucrose isomerase variants were expressed in Pichia pastoris X33. Thus, for the first time, we report the expression and characterization of glycosylated sucrose isomerases. The designed mutants K174Q, L202E and K174Q/L202E, showed an increase in their optimal temperature of 5 °C, while their half-lives increased 2.21, 1.73 and 2.89 times, respectively. The mutants showed an increase in activity of 20.3% up to 25.3%. The Km values for the K174Q, L202E, and K174Q/L202E mutants decreased by 5.1%, 7.9%, and 9.4%, respectively; furthermore, the catalytic efficiency increased by up to 16%.
Conclusions: With the comprehensive strategy followed, we successfully obtain engineered mutants more suitable for industrial applications than their counterparts: native (this research) and wild-type from E. rhapontici NX-5, without compromising the catalytic activity of the molecule.
SCDAP – Secured Cluster based Data Aggregation Protocol for Energy Efficient Communication in Wireless Sensor Networks
Authors: Gunasekaran Lavanya , Velammal B L , K Kulothungan 
Published: September 2022

AbstractA network of real time devices that can sense and transmit the information from the deployed environment by using multi hop communication is called as Wireless Sensor Network (WSNs). Despite the rapid advancement of WSN, where an increasing number of physical devices so called as sensors nodes are connected with each other, providing theimproved security withoptimized energy consumption during data transmission, communication and computation remains huge challenge. In wireless sensor networks, numerous sensor nodes are deployed in the physical environment to sense and collect the required information from the given environment. The sensed information are needed to be transmitted from the nodes to the control station in an energy efficient manner. Data aggregation is one kind of techniques which willoptimize the energy usage in wireless sensor networks during the data transmission. In data aggregation, the unnecessary data is removedwhich will significantly reduce energy of the nodes during data transmission. However, collected data during the data aggregation should be completely protected and there are various threats that can be launched by the intruders to carry out unauthorised data access and can cause threat to the integrity of the network. Therefore, ensuring data security during the data aggregation process is very important and essential for the security of the network. In this paper, a Secure Cluster based Data Aggregation Protocol (SCDAP) have been proposed to provide better security through secure authentication and verification process, and to reduce overall energy consumption of the network by implementing secure clustering process to eliminate the redundant data in the network. Moreover, the proposed system is more efficient in generating public and private keys for effective and secure data transmission and verification process. The proposed system is experimentally tested in NS3 tool and proves that the proposed system reduces high energy consumption, computational and communicational cost, end-to-end delay and improves the packet delivery ratio. Moreover, the proposed system provides better security in the network when compared to other existing systems during the data aggregation.
Establishment of a n efficient method for kiwifruit in vitro micrografting
Authors: Yao Wantian , Kong Lingling , Lei Diya , Zhao Bing , Tang Honglan , Zhou Xuan , Lin Yuanxiu , Zhang Yunting , Wang Yan , He Wen , Li Mengyao , Chen Qing , Luo Ya , Wang Xiaorong , Tang Haoru , Zhang Yong 
Published: September 2022

Abstract
This study was carried out to assess the potential use and applicability of micrografting technique for developing in vitro grafted plantlets. Microshoots of kiwifruit ‘Miliang-1’ and ‘Hongyang’ was used as rootstock and scion. Accomplishment of in vitro grafting has been examined by varying numerous factors, the physiological state of the rootstock and scion, the pH value of the medium, the concentration of sucrose, the type of medium and the PGRs. The results showed that the best condition of kiwifruit in vitro grafting was that the rootstock does not take root, and both the rootstock and scion have no leaves. The best medium formula suitable for kiwifruit micrografting was 1/2 MS solid media along with 0.5 mg L− 1 GA3, 1.0mg L− 1 IBA, 40 g L− 1 sucrose and 7 g L− 1 agar, pH 6.0. The matrix formula of perlite: peat soil: vermiculite volume ratio of 1:2:1 was the most suitable substrate for transplanting micrografted seedlings.
Synthesis of NiO nanoparticles prepared via a green process using Azadirachta indica, Morinda citrifolia, and Terminalia elliptica for biological applications
Authors: V Lakshmikanth Reddy , S Lakshmikanth 
Published: September 2022

Abstract
Developing a low cost, high-efficiency and environmentally friendly approach to synthesize nickel oxide (NiO) nanoparticles (NPs) for biomedical applications has become a research focus in the current scenario. In the present investigation, the NiO NPs were synthesised via a green process using different plant extracts, such as Azadirachta indica (N1), Morinda citrifolia (N2), and Terminalia elliptica (N3). X-ray diffraction (XRD), Field emission scanning electron microscopy (FESEM), Energy dispersive x-ray analysis (EDX), X-ray photoelectron spectroscopy (XPS), and photoluminescence excitation spectroscopy were used to investigate the evolution of the size, morphology, chemical composition, and surface defect of NiO NPs. The synthesized NiO NPs were exhibited as cubic structures. As compared to conventional antibiotics amoxicillin, Morinda citrifolia (N2) and Terminalia elliptica (N3) medicated NiO nanoparticles, Azadirachta indica mediated NiO (N1) exhibits more antibacterial activity. From the antioxidant activity, the DPPH assay of N1, N2, N3, and vitamin-c samples exhibited free radical scavenging potential. There are increases in the inhibition percentage with increases in the concentrations of these NiO NPs. In addition, the N1 sample demonstrates higher radical scavenging activity than N2 and N3. From the observed results, we believe that Azadirachta indica mediated N1 condition synthesized NiO NPs are very promising biocidal nanomaterials against human pathogens, which will be medically crucial for clinical applications.