bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Permasalahan Anak Berkebutuhan Khusus di Sekolah Inklusi SMP N 5 Kota Padang
Authors: Anggraini Batrik , Dwi Putri Besti Nora 
Published: February 2022

Sekolah inklusi merupakan layanan pendidikan yang layak, di sekolah inklusi memungkinkan anak berkebutuhan khusus belajar bersama dengan anak normal lainnya dan diperlakukan selayaknya anak normal lainnya. tujuan dilakukan penelitian ini yaitu untuk mendeskripsikan :1) permasalahan anak berkebutuhan khusus dari slow leaner dan 2) permasalahan anak berkebutuhan khusus dari anak speech delay. penelitian ini dilakukan menggunakan pendekatan kualitatif yang bersifat deskriptif, adapun informan penelitian ini adalah guru BK sebagai informan kunci dan guru mata pelajaran dan teman dekat anak berkebutuhan khusus sebagai informan tambahan. Instrumen penelitian dengan menggunakan pedoman wawancara. Data dianalisis dengan reduksi data, dispalay data dan penarikan kesimpulan. Â Â Hasil penelitian ini mengungkapkan bahwa:1) Anak slow leaner dalam hubungan interpersonal tidak mengalami masalah dan dalam keaktifannya anak tersebut kurang aktif, memiliki prestasi yang rendah. 2) Anak speech delay sulit untuk berkomunikasi secara verbal, sulit menangkap penjelasan yang diberikan oleh guru kecuali melihat gerak bibir.
Afiksasi Pembentuk Verba Dalam Karangan Deskripsi Siswa Kelas VII MTS Muhammadiyah Lebung Itam
Authors: Mahareta Desti , Abidin Zainal , Wardiah Dessy 
Published: February 2022

Masalah dalam penelitian ini menulis karangn deskripsi yang menganalisis afiksasi pembentuk verba dalam karangan deskripsi siswa VII MTs muhammadiyah lebung itam. Dalam pembelalaran bahasa Indonesia di kelas VII diarahkan untuk meningkatkan kemampuan siswa dalam membuat tulisan karangan deskripsi dalam bahasa Indonesia dengan baik dan benar, baik secara lisan maupun tulis,serta menumbuhkan apresiasi terhadap hasil karya sastra Indonesia. Tujuan penelitian untuk mendeskripsikan penggunaan afiksasi pembentuk verba dalam karangan deskripsi. Metode penelitian yang digunakan deskriptif kualitatif. Sumber data dalam penelitian ini adalah karangan deskripsi siswa kelas VIIÂ MTs Muhammadiyah Lebung Itam teknik pengumpulan data yang di gunakan teknik observasi dan dokumentasi. Tekniks analisis data yang digunakan yaitu analisis isi. Berdasarkan analisis data pembahasan tentang afiksasi pembentuk verba dalam karangan deskripsi dapat di simpulkan, pertama ditemukan 63 kata yang berafiks verba. Kedua terdapat siswa yang masih belum lengkap dalam menulis karangan deskripsi berdasarkan karangan.Â Kata kunci: afiksasi verba, karangan deskripsiÂ
Pengaruh Strategi Story Maps Terhadap Keterampilan Menulis Cerpen Siswa Kelas IX SMP Yayasan Harapan Ibu
Authors: Piani Septi , Puspita Yenni , Hetilaniar Hetilaniar 
Published: February 2022

Tujuan penelitian ini untuk mengetahui PengaruhÂ Strategi Story Maps Terhadap Keterampilan Menulis Cerpen Siswa Kelas IX SMP Yayasan Harapan Ibu. Teknik yang digunakan dalam penelitian ini adalah Posttes-Only Control Design dengan menggunakan tes akhir pada kelas eksperimen berjumlah 30 siswa dan kelas kontrol berjumlah 30 siswa. Teknik pengumpulan data menggunakan teknik tes, teknik wawancara. Diperoleh nilai tes akhir kelas eksperimen rata-rata 83,20. Nilai akhir rata-rata kelas kontrol adalah 73,36. Hal ini diperoleh dari hasil hitungan secara statistik pada uji t, hasil Â = 5,480 dengan dk = 29 pada taraf signifikan 0,05% sehingga dk = 2,04 jadi Â â‰¥Â Â = 5,480 â‰¥ 2,04 sehingga Â dinyatakan signifikan. Dapat dinyatakan Ho ditolak Ha diterima, yang berarti pengaruh yang signifikan strategi pembelajaran story maps terhadap keterampilan menulis cerpen. Selanjutnya pada uji homogenitas variabel penelitian diketahui nilai Levene Statistic sebesar 0,05, sedangkan nilai signifikan lebih besar dari 0,05 yaitu sebesar 0,060. Karena harga sig > 0,05 maka hipotesis yang menyatakan bahwa data diperolehÂ dari populasi yang homogen. Dengan demikian hipotesis yang peneliti kemukakan adalah â€œTerdapat PengaruhÂ Strategi Story Maps Terhadap Keterampilan Menulis Cerpen Siswa Kelas IX SMP Yayasan Harapan Ibuâ€ terbukti kebenarannya
Management of Nematodes with Cowpea Cover Crops
Authors: Grabau Zane Joseph , Rios Esteban 
Published: February 2022

Cover crops are grown between cash crop cycles, or intercropped with cash crops to cover the ground, such as in vegetable fields, orchards, groves, and agricultural sites. If used appropriately, cover crops can improve soil structure and fertility, decrease soil erosion, provide foliage and animal feed, and suppress crop pests such as weeds, insects, nematodes, and other plant pathogens. Residues from cover crops can be incorporated as green manure to supply nutrients and improve fertility for the next crop. Using cover crops can increase on-farm crop diversity, may enhance many beneficial organisms, and possibly even contribute to carbon sequestration. One good example of a summer cover crop is cowpea, Vigna unguiculata (L.) Walp, due to its fast establishment, abiotic and biotic stress tolerance, and biomass production. This publication is intended to guide agricultural professionals in the use of cowpea cover crops for managing plant-parasitic nematodes.
THERMO-PNEUMATIC MICROPUMP FOR DRUG DELIVERY APPLICATIONS
Authors: Hamid Norihan , Majlis B.Y , Yunas J , Ibrahim Mazree 
Published: February 2022

Micropumps constitute an essential part of precise delivery and directional volume control of fluid in a microfluidic system. In biomedical applications, micropump is widely used especially in drug delivery, biological fluid transmission, organic analysis, liquid measurement, and many more. In this paper, the concept and design structure hence fabrication of the Thermo pneumatic micropump prototype are explained. The experimental measurement of the micropump employing planar diffuser nozzle in transmits fluid is also presented. Thermopneumatic micropump is comprised of three different components which are the microheater on the bottom, the flexible thin membrane that acts as an actuator, and the planar diffuser nozzle on the top to channel the fluidic. These three components were fabricated separately due to the different materials and techniques used in each component. Finally, the whole micropump system was integrated using an anodic bonding technique. Bulk micromachining technique was used to fabricated the chamber and thin-film membrane, surface micromachining technique for the microheater while replica molding technique was used for the planar diffuser nozzle. The whole diameter size for the micropump was 25 x 20 x 1.6 mm respectively. The microscope image recorded video and data was used during the experimental measurement, to observed and calculate the flow rate of meniscus motion flow in the outlet tube of the micropump. At the end of the experiment, the flow rate range of the micropump measure was approximately 770pL to 12.5nL, when the output of 2-12Vdc was applied to the microheater. This flow rate range is very suitable for drug delivery applications.
The politics and practices of representing bodies in capitalism
Authors: Gálvez Alyshia , Saldaña Tejeda Abril , Vasquez Emily , Brady Jennifer , Yates-Doerr Emily 
Published: February 2022

This publication was produced from a roundtable discussion about the cultural politics of representation and metabolic illness commissioned by the organizers of the 2021 “Just Food” conference. The immediate occasion for the roundtable was a film that had been submitted to the conference titled, El Susto: Mexico’s Love Affair with Sugary Drinks Turns Deadly, produced by Karen Akins.
Just Food conference organizers wished to screen the film and provide an academic roundtable discussion to unpack some of the tropes that frequently surround discussions of globalized markets of processed foods and the rise of metabolic illness (see also, for example, the NYTimes multi-part series on the rise of “globesity”). With questions posed by the Chair, Emily Yates-Doerr, the roundtable discussion focused broadly on the challenge of problematizing the inequitable burden of metabolic illness among equity-seeking groups without stigmatizing those who consume foods that are often seen as the cause of disease. More specifically, panelists considered how to redress the corporate greed that drives expanding global markets for processed food, without pathologizing racialized and fat bodies. We jointly insisted that academic inquiry and activism should keep the focus on political and economic structures, such as trade agreements and health policies, that undergird health inequities, rather than individual dietary choice or a lack of education.
The roundtable panelists were selected by the Just Food conference organizers because of their expertise on metabolic disorder, the cultural practice of capitalism(s), and techniques of representation. Because we believe the conversation has relevance for anyone working on or thinking about health and its representation – in or outside of Mexico -- we are reproducing it here. We have lightly edited the transcript of the conversation to help with readability.
Podcasts: uma experiência acadêmica inovadora na graduação médica
Authors: Schaelder Augusto Wickert , Pina Thales Arthur Cotolengo de , Dantas Olinda Mara , Lemes Thamyres Brito de Miranda , Borges Mariana do Prado , Schaedler Guilherme Wickert , Rezende Felipe Batista , Machado Beatriz Gomes , Macedo João Lucas Rodrigues de , Pereira Rafael Santana , Gonçalves Itamar Magalhães , Sousa Bruno de Oliveira Araujo 
Published: February 2022

Objetivo: O estudo busca compreender como a produção de podcasts na formação médica contribui para uma aprendizagem acadêmica significativa. Metodologia: Obtém caráter qualitativo do tipo relato de experiência com foco na produção de podcast desde 2018 por alunos da Instituição de Ensino Superior (IES) paralelo a uma disciplina da grade curricular obrigatória do curso de medicina. Resultados e Discussão: As estratégias das metodologias ativas contribuem com o processo de ensino-aprendizagem, uma vez que incentiva o aluno a ser o protagonista da construção do seu conhecimento. O atual estudo demonstra a aplicabilidade e eficácia de ferramentas tecnológicas que permitem o ensino efetivo - como os podcasts - em tempos de adversidades como o enfrentado atual a COVID-19. Conclusão: Os podcasts desenvolvidos por acadêmicos geram uma inversão de papéis onde o aluno torna-se o protagonista do seu aprendizado fomentando um processo contextualizado e oportuno para a concretização do ensino na graduação. Diante da carência de estudos na literatura que relatam a utilização de podcasts no curso de medicina, pretende-se que esta proposta possa servir de referência para novas práticas.
Efektivitas Biomatriconditioning Benih Pratanam yang diintegrasikan dengan Aplikasi Pestisida Nabati terhadap Pertumbuhan dan Hasil Bawang Merah True Seed
Authors: Anaway F Anaway F , Bande La Ode Santiaji , Sutariati Gusti Ayu Kade 
Published: February 2022

Penggunaan true seed untuk produksi umbi bibit ataupun umbi konsumsi belum banyak dilakukan oleh petani bawang merah di Indonesia. Penyebabnya antara lain ketersediaan true seed masih terbatas dan belum ditemukannya teknologi pembibitan dan pembudidayaan bawang merah dari true seed yang efisien. Penelitian ini bertujuan untuk menganalisis efektivitas perlakuan biomatriconditioning pada true seed pratanam yang diintegrasikan dengan aplikasi pestisida nabati terhadap pertumbuhan dan hasil bawang merah. Penelitian ini menggunakan Rancangan Acak Kelompok Faktorial dengan faktor pertama yaitu agens hayati terdiri dari 4 taraf yakni tanpa perlakuan invigorasi (B0), arang sekam + Bacillus CKD061 (B1), arang sekam + Pseudomonas SWRII B02 (B2), arang sekam + Pseudomonas W2R06 (B3) dan faktor kedua yaitu aplikasi pestisida nabati terdiri atas 3 taraf yakni tanpa aplikasi pestisida nabati (P0), 4 kali aplikasi pestisida nabati (P1) dan 2 kali aplikasi pestisida nabati (P2). Variabel yang diamati adalah tinggi tanaman, jumlah daun, diameter batang, jumlah anakan, luas daun, laju asimilasi bersih, diameter umbi, berat segar umbi dan kesehatan tanaman. Data pengamatan dianalisis ragam dan data analisis yang menunjukkan pengaruh nyata atau sangat, dilanjutkan dengan uji jarak berganda duncan pada taraf nyata α = 0,05. Hasil penelitian menunjukkan bahwa secara mandiri perlakuan biomatriconditioning benih berpengaruh terhadap semua peubah yang diamati, sementara perlakuan aplikasi pestisida nabati hanya berpengaruh terhadap peubah jumlah daun, diameter batang, luas daun dan laju asimilasi bersih. Interaksi perlakuan biomatriconditioning benih dan aplikasi pestisida nabati berpengaruh terhadap tinggi tanaman, luas daun dan laju asimilasi bersih. Perlakuan terbaik diperoleh pada biomatriconditioning benih menggunakan isolat Bacillus CKD061 yang diintegrasikan dengan aplikasi pestisida nabati 2 kali (10 HST dan 30 HST).Kata kunci: Aplikasi pestisida nabati, Biomatriconditioning, true seed Kata kunci: Aplikasi pestisida nabati, Biomatriconditioning, true seed
Differential Proteomics of Cardiovascular Risk and Coronary Artery Disease in Humans
Authors: Ferrannini Ele , Manca Maria Laura , Ferrannini Giulia , Andreotti Felicita , Andreini Daniele , Latini Roberto , Magnoni Marco , Williams Stephen A. , Maseri Attilio , Maggioni Aldo P. 
Published: February 2022

BackgroundProteomics of atypical phenotypes may help unravel cardiovascular disease mechanisms.AimWe aimed to prospectively screen the proteome of four types of individuals: with or without coronary artery disease (CAD), each with or without multiple risk factors. Associations with individual risk factors and circulating biomarkers were also tested to provide a functional context to the protein hits.Materials and MethodsThe CAPIRE study (ClinicalTrials.gov Identifier: NCT02157662) is a cross-sectional study aimed at identifying possible new mechanisms promoting or protecting against atherothrombosis. Quantification (by aptamer technology), ranking (using partial least squares), and correlations (by multivariate regression) of ~5000 plasma proteins were performed in consecutive individuals aged 45–75 years, without previous cardiovascular disease, undergoing computed tomography angiography for suspected CAD, showing either &gt;5/16 atherosclerotic segments (CAD+) or completely clean arteries (CAD−) and either ≤ 1 risk factor (RF+) or ≥3 risk factors (RF−) (based on history, blood pressure, glycemia, lipids, and smoking).ResultsOf 544 individuals, 39% were atypical (93 CAD+/RF−; 120 CAD−/RF+) and 61% typical (102 CAD+/RF+; 229 CAD−/RF−). In the comparison with CAD+/RF− adjusted for sex and age, CAD−/RF+ was associated with increased atrial myosin regulatory light chain 2 (MYO) and C-C motif chemokine-22 (C-C-22), and reduced protein shisa-3 homolog (PS-3) and platelet-activating factor acetylhydrolase (PAF-AH). Extending the analysis to the entire cohort, an additional 8 proteins were independently associated with CAD or RF; by logistic regression, the 12-protein panel alone discriminated the four groups with AUCROC's of 0.72–0.81 (overall p = 1.0e−38). Among them, insulin-like growth factor binding protein-3 is positively associated with RF, lower BMI, and HDL-cholesterol, renin with CAD higher glycated hemoglobin HbA1c, and smoking.ConclusionsIn a CCTA-based cohort, four proteins, involved in opposing vascular processes (healing vs. adverse remodeling), are specifically associated with low CAD burden in high CV-risk individuals (high MYO and C-C-22) and high CAD burden in low-risk subjects (high PS-3 and PAF-AH), in interaction with BMI, smoking, diabetes, HDL-cholesterol, and HbA1c. These findings could contribute to a deeper understanding of the atherosclerotic process beyond traditional risk profile assessment and potentially constitute new treatment targets.
Associations of Triglycerides/High-Density Lipoprotein Cholesterol Ratio With Insulin Resistance, Impaired Glucose Tolerance, and Diabetes in American Adults at Different Vitamin D3 Levels
Authors: Liu Yuanyuan , Gong Rongpeng , Luo Gang , Li Jinxia , Li Qidan , Yang Lixin , Wei Xiaoxing 
Published: February 2022

BackgroundPrevious studies have shown that vitamin D3 (VD3) may be a protective factor for diabetes mellitus (DM), while triglycerides/high-density lipoprotein (TG/HDL) may be a risk factor for diabetes. However, no existing study has elucidated the interaction between TG/HDL and VD3. Therefore, this work aimed to investigate the relationships of TG/HDL with insulin resistance (IR), impaired glucose tolerance (IGT), and DM at different VD3 levels.MethodsWith the use of the data from five National Health and Nutrition Examination Survey (NHANES) cycles, a total of 2,929 males and 3,031 females were divided into 4 groups according to their VD3 levels. Logistic regression was performed to observe the associations of TG/HDL ratio with IR, IGT, and DM in different groups.ResultsThe relationships of TG/HDL with IR, IGT, and DM showed a threshold effect, with the cutoff values of 1.094, 1.51, and 1.11, respectively. On both sides of the cutoff values, the correlation was first weakened and then enhanced with the increase in VD3 levels.ConclusionTG/HDL is a risk factor for IR, IGT, and DM. Both too low and too high levels of VD3 can strengthen this association, whereas keeping VD3 at a reasonable level helps to reduce the associations of TG/HDL with IR, IGT, and DM.
C-Reactive Protein Levels Predict Responses to PD-1 Inhibitors in Hepatocellular Carcinoma Patients
Authors: Zhang Yiyang , Lu Lianghe , He Zhangping , Xu Zhishen , Xiang Zhicheng , Nie Run-Cong , Lin Wenping , Chen Wenxu , Zhou Jie , Yin Yixin , Xie Juanjuan , Zhang Youcheng , Zheng Xueyi , Zhu Tianchen , Cai Xiaoxia , Li Peng , Chao Xue , Cai Mu-Yan 
Published: February 2022

BackgroundSerum C-reactive protein (CRP) is a biomarker of an acute inflammatory response and has been successfully used as a prognostic predictor for several malignancies. However, the clinicopathological significance of CRP levels in hepatocellular carcinoma (HCC) patients being treated with PD-1 inhibitors remains unclear.MethodsSerum CRP levels were measured for a total of 101 HCC patients that had been treated with PD-1 inhibitors from July 2018 to November 2019. The clinicopathological data was retrospectively analyzed to identify any clinical implications between CRP levels and responses to PD-1 inhibitors and patients’ progression-free survival (PFS).ResultsThe median PFS was 8.87 months in the CRP-low subgroup and 3.67 months in the CRP-high subgroup (P = 0.009). Univariate and multivariate Cox regression analysis demonstrated that both serum CRP and AFP levels were independent risk factors for the PFS of HCC patients treated with PD-1 inhibitors (P &lt; 0.05). Moreover, Cox regression analysis after Propensity Score Matching showed the similar results. A prognostic model combining CRP and AFP levels could significantly stratify HCC patients receiving PD-1 inhibitors into low-, intermediate-, and high-risk subgroups (P &lt; 0.001). Patients in the risk subgroups reported similar overall response rates (P = 0.625) and significantly different disease control rates (low- vs. intermediate- vs. high-risk groups: 81.6% vs. 65.1% vs. 35%, respectively, P = 0.002).ConclusionsThe results of this study support the association between high serum CRP levels with the response and PFS for HCC patients receiving PD-1 inhibitors. Furthermore, the levels of both CRP and AFP in an HCC patient before treatment initiation show great potential for determining the efficacy of PD-1 inhibitors.
Primary Immune Deficiency: Patients’ Preferences for Replacement Immunoglobulin Therapy
Authors: Gonzalez Juan Marcos , Ballow Mark , Fairchild Angelyn , Runken Michael Chris 
Published: February 2022

PurposeImmunoglobulin (Ig) replacement therapy is an important life-saving treatment modality for patients with primary antibody immune deficiency disorders (PAD). IVIG and SCIg are suitable alternatives to treat patients with PAD but vary in key ways. Existing evidence on patient preferences for Ig treatments given the complexities associated with IVIG and SCIg treatment is limited and fails to account for variations in preferences across patients. For this reason, we sought to evaluate PAD patient preferences for features of IVIG and SCIg across different patient characteristics.Materials and Methods119 PAD patients completed a discrete-choice experiment (DCE) survey. The DCE asked respondents to make choices between carefully constructed treatment alternatives described in terms of generic treatment features. Choices from the DCE were analyzed to determine the relative influence of attribute changes on treatment preferences. We used subgroup analysis to evaluate systematic variations in preferences by patients’ age, gender, time since diagnosis, and treatment experience.ResultsPatients were primarily concerned about the duration of treatment side effects, but preferences were heterogeneous. This was particularly true around administration features. Time since diagnosis was associated with an increase in patients’ concerns with the number of needles required per infusion. Also, patients appear to prefer the kind of therapy they are currently using which could be the result of properly aligned patient preferences or evidence of patient adaptive behavior.ConclusionsHeterogeneity in preferences for Ig replacement treatments suggests that a formal shared decision making process could have an important role in improving patient care.
Case Report: Acute Kidney Injury Due to Chronic Milk-Alkali Syndrome in a Patient With Colon Cancer
Authors: Lee Hyo Jin , Yoon Seokho , Choi Bong-Hoi , Lee Seunghye , Jung Sehyun , Jang Ha Nee , Chang Se-Ho , Kim Hyun-Jung 
Published: February 2022

BackgroundCommon causes of hypercalcemia include primary hyperparathyroidism and paraneoplastic syndrome of malignancy. Because of this, physicians can easily miss extrinsic causes of hypercalcemia such as milk-alkali syndrome in patients with cancer. We successfully treated a case of acute kidney injury due to severe hypercalcemia caused by milk-alkali syndrome due to long-term milk drinking in a patient with colon cancer.Case DescriptionA 62-year-old man was referred to nephrology for hypercalcemia and azotemia that was found during preoperative evaluation for colon cancer surgery. The patient had experienced several months of dizziness and anorexia. We started hemodialysis because hypercalcemia and azotemia were not improved despite large amounts of hydration and diuretics. We suspected paraneoplastic syndrome because of concomitant colon cancer and low intact parathyroid hormone (PTH). Renal microcalcifications were observed on ultrasonography. Metastatic calcifications of the lung and stomach were present, but no malignant metastasis appeared on bone scans. There was no evidence of metastatic malignant lesions on chest or abdominal enhanced computed tomography. PTH-related peptide was not detected. Thus, other causes of hypercalcemia beyond malignancy were considered. On history-taking, the patient reported consuming 1,000 to 1,200 mL of milk daily for the prior 3 months. Hypercalcemia was due to chronic milk-alkali syndrome. We advised withdrawal of milk and nutritional pills. Hemodialysis was stopped after 2 weeks since azotemia and hypercalcemia were resolving. Acute kidney injury was improved, and mild hypercalcemia remained when he underwent hemicolectomy after 1 month. Thereafter, serum calcium and creatinine remained normal at discharge and follow-up for 1 year in the outpatient clinic. However, lung calcifications still remained on bone scan after 1 year.ConclusionsChronic milk-alkali syndrome is a rare condition resulting from excessive calcium and alkali intake through various routes, like milk, nutritional supplements, and medicines for osteoporosis. Therefore, early management for hypercalcemia should include precise history taking including diet, previous diagnoses, and current medications.