bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional Anatomy of the Auditory Tube: What is Important to Know? Analytical Literature Review
Authors: Еременко Ю.Е. , МакаринКибак А.С. , Бурчук Н.Ю. 
Published: March 2022

Дисфункция слуховой трубы (ДСТ) – частая причина многих патологических состояний и заболеваний среднего уха. По статистическим данным США, с проблемой ДСТ ежегодно обращается порядка 2 миллионов взрослых пациентов. В настоящее время механизмы функционирования различных отделов слуховой трубы (СТ) активно обсуждаются в мировом сообществе оториноларингологов. Понимание патогенеза ДСТ основано на знаниях анатомии и физиологии слуховой трубы. В статье освещены особенности анатомии и физиологии СТ. Цель статьи – систематизация имеющихся в литературе данных по анатомии СТ, актуализация знаний особенностей анатомии СТ при диагностике и выборе тактики лечения ее патологии.
Auditory tube dysfunction (ATD) is a common cause of many pathological conditions and diseases of the middle ear. According to the US statistics, about 2 million adult patients treat the problem of ATD annually. Currently, the mechanisms of functioning of various parts of the auditory tube (AT) are actively discussed in the world community of otorhinolaryngologists. Understanding the pathogenesis of ATD is based on the knowledge of the anatomy and physiology of the AT. The article highlights the features of the anatomy and physiology of AT.The purpose of the article is to systematize the data on the AT anatomy available in the literature, update the knowledge of the peculiarities of the AT anatomy in diagnostics and treatment of its pathology.
Radiation Diagnostics of Pathological Changes in Oncohematological Patients with Skin Lesions (Case Report)
Authors: Троян В.А. , Козырев С.В. , Асеева И.А. , Ламоткин И.А. , Бобин А.Н. , Сапельникова Э.Р. , Трофимчук И.В. , Алексеев С.А. , Новоселова Н.А. , Сарачан Д.А. , Турусинова Ю.С. , Рукавицын О.А. 
Published: March 2022

В представленной вашему вниманию статье освещен клинический случай лимфомы Ходжкина (ЛХ) с поражением экстралимфатических органов, в частности кожи. Диагноз был установлен с помощью гистологического и иммуногистохимического исследований. Используя ультразвуковое исследование, были выявлены и продемонстрированы сонографические особенности поражений кожи и подкожно-жировой клетчатки, характерные для данного заболевания. Представлены возможности комплексного применения таких методов лучевой диагностики, как рентгенография, компьютерная томография (КТ), позитронно-эмиссионная томография, совмещенная с компьютерной томографией c применением фтордезоксиглюкозы, меченной 18-фтором (ПЭТ/КТ с18F-ФДГ). Применение вышеуказанных методов позволило оценить степень распространения поражений, установить стадию заболевания, а также в динамике оценить патологические изменения, характерные для лимфогранулематоза. В данном клиническом примере был зарегистрирован хороший клинический ответ на проводимую химиотерапию.
The article presents a clinical case of Hodgkin’s lymphoma with damage to extralymphatic organs, particularly skin. The diagnosis was established hystologically and immunohystochemically. The sonographic features of skin and subcutaneous fat lesions characteristic of this disease were revealed and demonstrated using ultrasound examination. This article presents the possibilities of the complex application of methods of radiation diagnostics such as x-ray, computed tomography, positron emission tomography combined with computed tomography using fluorodeoxyglucose labeled with 18-fluorine (PET/CT with 18F-FDG). The use of these methods allowed to assess the extent of lesions’spread, to establish the stage of the disease and dynamically assess the pathological changes. A good clinical response to therapy was registered in this clinical case.
Barrier Function of Skin at Atopic Dermatitis: Role of Filaggrin
Authors: Адаскевич В.П. 
Published: March 2022

Рост заболеваемости АД указывает на важную роль взаимодействия генетических факторов и факторов окружающей среды в развитии данного заболевания. Предположение, что первопричиной АД является нарушение эпидермального барьера, привлекло интерес исследователей к изучению генов, регулирующих барьерную функцию кожи. Наиболее существенные для патогенеза АД результаты показало исследование генов, кодирующих структурные белки эпидермального барьера, в ходе которого были выявлены наиболее значимые для заболевания генетические факторы, а именно мутации с потерей функции гена FLG, кодирующего профилаггрин, предшественник структурного белка филаггрина. Значение филаггрина в восстановлении поврежденного эпидермального барьера во многом зависит от его ведущей роли в образовании естественного увлажняющего фактора, влияющего на способность кератиноцитов удерживать воду и поддерживать баланс уровня рН. В результате активных поисков средств, стимулирующих выработку филаггрина, в терапевтическом арсенале появился филагринол – комбинация растительного масла проросших зерен пшеницы, оливкового масла и масла сои.
The increase in the incidence of AD indicates the important role of the interaction of genetic factors and environmental factors in the development of this disease. The assumption that the root cause of AD is a violation of the epidermal barrier has attracted the interest of researchers in the study of genes that regulate the barrier function of the skin. The most significant results for the pathogenesis of AD were obtained from the study of genes encoding structural proteins of the epidermal barrier, during which the most significant genetic factors for the disease were identified, namely, mutations with loss of function of the FLG gene encoding profilaggrin, a precursor of the structural protein filaggrin. The importance of filaggrin in the restoration of the damaged epidermal barrier largely depends on its leading role in the formation of a natural moisturizing factor that affects the ability of keratinocytes to retain water and maintain pH balance. As a result of an active search for agents that stimulate the production of filaggrin, filagrinol appeared in the therapeutic arsenal – a combination of vegetable oil of sprouted wheat grains, olive oil and soybean oil.
الرقابة الجبائية الاتحادية في مجال الضرائب وسبل إصلاحها في العراق
Authors: فاضل محمد عزت 
Published: March 2022

تكون الرقابة الاتحادية ناجحة في تحصيل الضرائب عندما توفر الوقت والمال, وتميل غالبية النظم الفيدرالية الى اعتماد الادارة المباشرة في تطبيق قوانين الضرائب الاتحادية لتمويل الانفاق العام. وان الرقابة المركزية ستمنع الفساد الاداري والتنافس الضريبي داخل الاتحاد.
وفي العراق تختص حكومات الاقاليم وفق دستور 2005 بجمع الضرائب الاتحادية وتحت اشراف ديوان الرقابة المالية الاتحادي, ويتطلب اصلاح الرقابة كفاءة الادارة, وتخفيف البيروقراطية, والشفافية, والتنسيق الفيدرالي.
The Effect Of Adding Latex And Hair Fiber On Concrete
Authors: Hendrik  
Published: March 2022

Along with the development of the construction world, the need for concrete is increasing and the scale of development shows that there will also be more and more concrete needs in the future, thus affecting the development of concrete technology which will demand new innovations regarding the concrete itself. In the construction of high-rise buildings required concrete with high compressive strength. However, to get good quality concrete, high costs are also required. So in this study, an economical additional material will be used which will be added to the concrete in the form of latex and hair fiber.
Testing of materials and test objects is carried out in accordance with the applicable Indonesian National Standard (SNI). The latex used is liquid latex. First, the hair fiber is washed in order to clean the dirt and debris attached and then dried in the sun for 2 days, then cut to a size of ± 30 mm. By adding latex with variations of 0.25%, 0.5% and 0.75% it is expected to achieve a concrete quality of 20 MPa and by adding 2% hair fiber and latex with variations of 0.25%, 0.5% and 0.75% is expected to achieve a concrete quality of 20 MPa. The research object used a cylinder with a diameter of 15 cm and a height of 30 cm with the addition of 48 pieces of latex which were tested at the age of 28 days, cylinder with a diameter of 15 cm and a height of 30 cm with the addition of latex and hair fiber as many as 18 pieces were tested at the age of 7 days, and a beam without reinforcement with a length of 60 cm, width 15 cm and height of 15 cm with the addition of latex and hair fiber as much as 3 pieces The Water Cement Factor (FAS) in this study was locked at 0.5. This study was intended to obtain the value of compressive strength, split tensile strength, concrete absorption, slump value in cylinders and flexural strength values ​​in unreinforced beams. From the test results, it was found that the slump value decreased due to the addition of the latex additive and increased due to the addition of the latex and hair fiber additives and then increased along with the increase in the additional variation. The absorption of concrete also decreased with the addition of the latex additive and increased with the addition of the latex additive and hair fiber. The most optimum compressive strength results were obtained in concrete with the addition of 0.75% latex variation, an increase of 13.226% from normal concrete while the most optimum compressive strength results were obtained in concrete with the addition of 0.75% latex variation and 2% hair fiber reduced by 0.94% from normal concrete.
Dificuldades enfrentadas por docentes do ensino superior frente ao contexto da pandemia de COVID-19
Authors: Thalita Targino dos Santos Jennifer , Assunção-Luiz Alan Vinicius , Eburneo Pereira Alison Luis , Barbosa Luciano Anderson Ricardo Malmonge , Carvalho Filho Idinei Francisco Pires de , Lima Santos Milena Jorge Simões Flória , Garbin Mônica Cristina 
Published: March 2022

A pandemia do COVID-19 modificou o cronograma de atividades propostas para o ano letivo de 2020-21, a partir da substituição das aulas presenciais pelo ensino remoto emergencial (ERE). Para os professores do ensino superior, embora as boas práticas de ensino sejam uma preocupação constante das universidades, surgiram desafios diante do modo repentino de transição e implementação do ERE. Nesse sentido, este estudo objetivou investigar as principais dificuldades encontradas por docentes do ensino superior no Brasil, frente ao ERE durante a pandemia de COVID-19. A coleta de dados ocorreu entre dezembro de 2020 e fevereiro de 2021, utilizando-se um questionário eletrônico constituído por 21 questões objetivas. Participaram do estudo 234 docentes. Deste total, 77,4% dos participantes apresentaram dificuldades durante o processo de adaptação para o ERE, sendo estas relacionadas a falta de capacitação ou de recursos tecnológicos por parte das instituições; problemas com o uso de tecnologias digitais (ferramentas e softwares); influência de dificuldades psicológicas; dificuldades associadas à burocracia administrativa ou com Segurança de Dados. Elucida-se que a transição deve ser realizada com planejamento e investimento na formação adequada dos professores, para que a educação em contexto virtual alcance o mesmo sucesso dos encontros presenciais.
Índice SatO2/FiO2 versus PaO2/FiO2 para predecir mortalidad en pacientes con COVID-19 en un hospital de altura
Authors: Marmanillo Mendoza Gabriela , Zuñiga Manrique Rosario Elsa Jesús , Cornejo Del Valle Oscar Eduardo , Portilla Canqui Luis Alberto 
Published: March 2022

Objetivo: comparar el índice SatO2/FiO2 versus PaO2/FiO2 para predecir mortalidad en pacientes con COVID-19 en un hospital de altura.
Materiales y métodos: estudio observacional, retrospectivo y transversal, donde se compararon la sensibilidad (S), especificidad (E), valor predictivo positivo (VPP) y valor predictivo negativo (VPN) de ambos índices.
Resultados: La edad promedio de los pacientes con COVID-19 fue 62.2 ±12.8 años, el 73.7% fueron varones, las comorbilidades de mayor frecuencia fueron la diabetes mellitus (21.6%) y la hipertensión arterial (27.2%). Por otro lado el índice promedio SatO2/FiO2 fue 234.9 ±121.9 y el PaO2/FiO2 fue 169.7 ± 84 y el 30.5% de pacientes falleció. Se evidenció relación significativa entre los índices en mención y la mortalidad. Se obtuvo como puntos de corte 114.4 para SatO2/FiO2, con sensibilidad de 43.1%, especificidad de 91.2%, valor predictivo positivo de 68.3% y valor predictivo negativo de 78.5%, mientras que el punto de corte para PaO2/FiO2 fue 134.2, con sensibilidad de 63.1%, especificidad de 67.6%, valor predictivo positivo de 46.1% y valor predictivo negativo de 80.7%.
Conclusión: Ambos índices son predictores de mortalidad, sin embargo el SatO2/FiO2 presentó mejores valores, con respecto a algunos de los criterios de sensibilidad, especificidad, valor predictivo positivo y valor predictivo negativo.
Follow-up study on indoor radon levels in Irish schools after a National School Survey and remediation programme
Authors: Gunning Gillian , Fuente Marta , Gunning Robert , Long Stephanie , Finch Eric , Foley Mark 
Published: March 2022

Background: A National Survey of Radon in Irish Schools was carried out by the Department of Education and the Environmental Protection Agency (EPA) (formerly the Radiological Protection Institute of Ireland) between 1998 and 2004. Then, a remediation programme was developed and implemented in the schools with elevated radon levels.
Objectives: To determine the durability of the remediation systems 10–17 years post-installation and to study the effect of radon awareness on follow-up programmes, radon retests were performed in 16 schools that had some form of remediation implemented.
Design: The schools were chosen based on the data of the National Survey for Irish Schools and the post-remediation survey. A total of 276 rooms were tested for radon using CR-39 etched track detectors supplied by the EPA. Short questionnaires were given to the school principals to gather information about the level of radon awareness, remediation maintenance and retesting policies.
Results: An increasing trend in the radon concentration with time was found in some schools. Potential factors contributing to this rise are lack of maintenance, lack of follow-up testing programmes and knowledge lost due to staff turnover. The results showed that 26% of the rooms which had remediation installed had risen to above the Department of Education’s reference level for schools of 200 Bq/m3 again and 10% to above 400 Bq/m3. Through case studies and questionnaires, radon awareness in schools was observed to be correlated with an ability to maintain radon concentrations below the reference level. Although the National Survey of Radon in Irish Schools is to be commended for its exhaustive completeness, many schools in this project were unaware of the remediation system installed. Only 15% of the schools in this study remember or have records of regularly checking or servicing their remediation systems.
Conclusions: Retesting for radon is crucial in indicating where remediation methods are less effective or have failed. A follow-up programme to retest for radon and to ensure maintenance of remediation systems should be implemented.
National projects as an adaptation mechanism of financial interaction between the state and corporations
Authors: Ludinova Yu. V. , Rumyantseva A. Yu. , Tarutko O. A. 
Published: March 2022

Aim. The presented study aims to assess the prospects for the participation of the corporate sector in achieving the target indicators of national project implementation in the context of increased volatility and to provide practical recommendations for realizing such opportunities.Tasks. The authors analyze the dynamics of the Russian private infrastructure investment market; investigate trends related to the investment climate and the advantages of monitoring and controlling the implementation of national projects using a project management information system; identify obstacles to attracting private capital in national projects; propose solutions that can have a positive impact, expanding the boundaries of financial interaction between the public and corporate finance sectors.Methods. This study uses a dialectical systems approach and general scientific methods. The analysis is based on the international scientometric database Scopus and the bibliographic database of the Russian Science Citation Index (RSCI).Results. The authors substantiate the need to attract private capital as one of the most important elements of national project efficiency and formulate practical recommendations for realizing the potential of the corporate sector within the framework of financial cooperation with the state in the implementation of national projects. Business involvement can positively influence both the target indicators and the rate of economic growth and development in general.Conclusions. Based on a study of financial interaction between the state and corporate finance, the authors identify obstacles to attracting private capital in national projects. Furthermore, based on the identified opportunities for financial interaction, solutions are proposed that can have a positive impact, expanding the boundaries of financial interaction between the public and corporate finance sectors.
Factors affecting the quality of commercial services
Authors: Gutnikova O. N. 
Published: March 2022

Aim. The presented study aims to investigate the essence of factors and the degree of their influence. Based on this information, the authors aim to determine criteria for identifying classification features and to substantiate the need for a clear ranking of these factors as part of a general methodology for assessing the quality of commercial services.Tasks. The study analyzes existing scientific approaches to the classification of factors affecting the quality of commercial services, develops an original classification, and proposes measures aimed at reducing the negative impact on the overall level of commercial services.Methods. This study is based on the principles of fundamental theoretical and practical research in the field of systematization of factors affecting the quality of service and the degree of their influence, as well as theoretical methods of cognition, including deduction and abstraction.Results. Several scientific approaches of Russian scientists and economists to the classification of factors affecting the quality of commercial services and the overall level of commercial services are investigated. An original classification of factors is developed, and a correlation between the quality of services and the competitiveness of the enterprise is revealed. Consumer perception of the quality of commercial services under the influence of external and internal factors is investigated. Measures aimed at reducing the negative impact of factors on the quality of commercial services are proposed.Conclusions. The proposals formulated in the study can be used in identifying tools and methods for analyzing the quality of commercial services as well as in developing a general methodology for assessing the level of commercial services within the framework of existing regulatory legal acts, including state standards.
Multimorbilidad y síndromes geriátricos: su efecto sobre la mortalidad en adultos mayores con sepsis
Authors: Muñoz-Lombo Jenny Patricia , Tabares-Burbano Adrián , Ocampo-Chaparro José Mauricio , Carvajal-Ortiz Reynaldo , Casanova-Valderrama María Eugenia , Reyes Ortiz Carlos Alfonso 
Published: March 2022

Introducción: la sepsis se diagnostica en más del 60% de los adultos mayores (AM) en el mundo. Estos AM con frecuencia presentan multimorbilidad y alguno de los síndromes geriátricos, llevando a discapacidad física, cognitiva y psicosocial, lo cual produce altos costos para los sistemas de salud, resultando en un problema grave de salud pública.
Objetivo: identificar el impacto de la multimorbilidad y los síndromes geriátricos en la mortalidad de AM hospitalizados por sepsis en una unidad geriátrica de agudos a 30 días de su ingreso.
Materiales y métodos: Estudio observacional, analítico de casos y controles anidado en una cohorte.
Resultados: Se analizaron 238 pacientes con edad media de 83,15±7.12 años, 52,1% fueron mujeres y el 99% tenían al menos una comorbilidad, la mortalidad a 30 días fue del 34%. La infección urinaria fue la causa principal de hospitalización (42,9%) obteniendo un aislamiento microbiológico en el 43,3% de los casos siendo la Escherichia coli el agente causal más frecuente (46,6%). La regresión logística múltiple mostro que la enfermedad renal crónica (OR 2,1 IC 95% 1,1-4,8; p=0,037), el delirium (OR 3,1 IC 95% 1,6-5,8; p=0,001) y la discapacidad (índice de Barthel <60; OR 3,4 IC 95% 1,5-7,5; p=0,002) se asociaron de manera significativa con la mortalidad a 30 días desde el ingreso a la unidad geriátrica de agudos en paciente con sepsis.
Conclusión: En los AM hospitalizados por sepsis, la multimorbilidad y los síndromes geriátricos representados por la enfermedad renal crónica, delirium y discapacidad fueron los predictores de mortalidad a 30 días.
Keefektifan Teknik Modeling Untuk Mengembangkan Kesadaran Karier Siswa Sekolah Dasar
Authors: Multisari Widya , Hafina Anne , Budiamin Amin 
Published: March 2022

Kesadaran karier merupakan tahapan perkembangan karier masa anak-anak yang berpengaruh terhadap perkembangan kariernya dimasa mendatang. Penelitian dilaksanakan berdasarkan fenomena kurangnya kesadaran karier siswa SD. Penelitian bertujuan menguji keefektivan teknik modeling untuk mengembangkan kesadaran karier siswa SD. Metode penelitian yakni kuasi eksperimen dengan desain penelitian nonequivalent pre test and post test control group design. Partisipan penelitian adalah siswa kelas V SD Muhammadiyah Ponorogo. Pengumpulan data menggunakan instrumen tingkat kesadaran karier. Pengujian efektivitas teknik modeling untuk mengembangkan kesadaran karier siswa dengan menggunakan rumus uji-t. Berdasarkan hasil ujicoba dan analisis uji data sebelum dan setelah pelaksanaan layanan terbukti bahwa teknik modeling secara empiris dapat mengembangkan kesadaran karier siswa. Keefektifan teknik modeling diketahui dengan adanya peningkatan rata-rata skor yang lebih tinggi pada kelompok eksperimen pada saat pretes dan postes. Sehingga terdapat perkembangan yang positif terhadap tingkat kesadaran karier siswa. Kefektifan teknik modeling dapat meningkatkan kesadaran karier pada tiga aspek yakni pemahaan diri, pendidikan dan eksplorasi pekerjaan dan perencanaan karier yang telah dijelaskan perubahannya pada setiap indikator.
Błąd Epimeteusza? Teatr w sieci technik i technologii
Authors: Duda Artur 
Published: March 2022

Artykuł stanowi prezentację najnowszej książki Williama B. Worthena Shakespeare, Theatre, Technicity (Cambridge, 2020), która jest próbą refleksji nad teatrem inscenizującym Shakespeare’a w epoce dominacji mediów cyfrowych. Praca znanego szekspirologa stanowi ważny głos w dyskusji nad teatrem jako hipermedium, czyli medium sięgającym po inne media, aby ustanowić swoją historyczną wersję w danej epoce. Koncepcja Worthena znajduje zakotwiczenie nie tylko w teoriach medioznawców, lecz nade wszystko w filozofii Bernarda Stieglera, który ujmuje człowieka jako istotę techniczną posługującą się materialno-technicznymi protezami (prostheses), aby przekroczyć własne bycie ku śmierci i móc istnieć poza uwarunkowaniami czysto biologicznymi. Jednym z istotnych argumentów Worthena za tym, aby uznać teatr za hipermedium, jest obszerna analiza praktyk, mitów i dylematów związanych z rekonstrukcją tradycyjnego teatru elżbietańskiego, które definiuje jako praktyki remediacyjne.