bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Nature of “Searching” Vortices in Fluidic Logic Driven by a Switching Jet
Authors: Strasser Wayne 
Published: February 2022

Abstract
Fluctuating jets energized by local excitations can perform operations similar to those of electric circuits but without electricity or moving parts. Some have termed these circuits “fluidic computers.” It is known that fluidic logic in a bistable two-channel splitter arrangement can occur at predictable frequencies, but uncertainty surrounds the internal flow character and how fine-scale hydrodynamic details control its self-driven oscillations. Additionally, flow rates, switching frequencies, and switching pressures “chosen” by the fluidic logic are not known a priori. A joint computational/experimental study has revealed that three families of vortex rollers compete for space and momentum, searching for preferred trajectories. The rollers were strongly three-dimensional (3D) like horseshoe vortices, but vortex tube spanwise asymmetry, in an otherwise symmetrical flow passage, was pervasive during vortex searching. Bending and localized compression were evident. Reynolds stress analysis revealed that streamwise autocorrelation dominated much of the oscillation cycle, with wall-normal normal stresses being slightly lower and then spanwise normal stresses being about half of that; uv stresses generally changed signs when the jet flipped directions. The mechanism by which the flow naturally cycles between a direct and indirect flow passage without any external influence is discovered. Specifically, at discharge pressures exceeding ≈18% or below ≈8% of the feed total pressure, conditions are favorable for the searching vortices to choose an alternate path, engaging the cyclical fluid switch and rerouting the jet up to approximately half of its maximum deflection.
Pulley Rupture in Rock Climber after Collagenase Treatment for Dupuytren Contracture
Authors: DEGREEF Ilse , KELLENS Sebastiaan 
Published: February 2022

Pulley injuries and Dupuytren disease are quite common in rock climbing. We report a rock climber who was treated for a Dupuytren contracture with collagenase injection therapy. Two months later, he developed a traumatic pulley injury during climbing and was treated with a ring orthosis. However, the finger contracture deteriorated and both a recurrent pulley rupture and a second pulley rupture were diagnosed. We were unable to find any reports on the use of collagenase in rock climbers with Dupuytren disease. We report a case of pulley rupture in a rock climber, treated for Dupuytren contracture in the treated and an adjacent finger, 2 months after the injection of collagenase. Level of Evidence: Level V (Therapeutic)
Under- and Normal-Weight Patients Are More Susceptible to Recurrence of Phyllodes Tumor
Authors: Kim Yong Yeup , Kim Hayeon , Kim Woo Young , Chung Jai Hyun , Lee Jae Bok , Woo Sang Uk 
Published: February 2022

Purpose. Phyllodes tumors (PTs) of the breast are rare fibroepithelial neoplasms, and factors associated with the recurrence of PTs are poorly understood. This study sought to identify clinicopathological factors associated with the recurrence of PTs. Method. From January 2009 to December 2019, we identified 100 patients who underwent definitive surgery for PT. Clinicopathological risk factors associated with the recurrence of PT were assessed. Results. The median age of the patients was 44 y (range, 19–62 y), and the median tumor size was 4 cm (0.8–30 cm). At a median follow-up of 26.7 mo (0–103 mo), 22 of the 100 patients experienced local recurrence. In the univariate and multivariate analyses, body mass index ≥ 23 kg/m2 (

P

= 0.042 in the univariate analysis;

P

= 0.039 in the multivariate analysis), tumor size ≥ 5 cm (

P

= 0.006 in the univariate analysis;

P

= 0.036 in the multivariate analysis), and the presence of stromal overgrowth (

P

= 0.032 in the univariate analysis;

P

= 0.040 in the multivariate analysis) were associated with an increased risk of local recurrence. Resection margins and grade were not associated with local recurrence. Conclusion. Normal- or underweight patients and those with larger tumor sizes were more prone to local recurrence. Further larger, multicenter studies with a long-term follow-up are required.
The Gut-Liver Axis in Nonalcoholic Fatty Liver Disease: Association of Intestinal Permeability with Disease Severity and Treatment Outcomes
Authors: Zhuang Yu-Pei , Zhang Yi-Ting , Zhang Ruo-Xin , Zhong Hao-Jie , He Xing-Xiang 
Published: February 2022

Objective. To investigate the association between intestinal permeability and severity of nonalcoholic fatty liver disease (NAFLD) and the value of intestinal permeability in predicting the efficacy of metabolic therapy for NAFLD. Methods. Disease severity was compared between patients with normal and elevated intestinal permeability; correlations between D-lactate and different NAFLD parameters were analyzed; and the effects of metabolic therapy on NAFLD patients with normal and elevated intestinal permeability were evaluated. Results. A total of 190 patients with NAFLD were enrolled. NAFLD patients with elevated intestinal permeability had significantly higher levels of liver test parameters, liver ultrasonographic fat attenuation parameter, triglyceride, homeostasis model assessment of insulin resistance value, and diamine oxidase (all P˂0.05) than NAFLD patients with normal intestinal permeability. Furthermore, serum D-lactate levels were positively correlated with alanine transaminase, aspartate transaminase, gamma-glutamyl transpeptidase, total bilirubin, indirect bilirubin, fat attenuation parameter, triglyceride, and diamine oxidase (all

P

˂ 0.05). Moreover, NAFLD patients with elevated intestinal permeability showed less improvement in TG levels (

P

= 0.014) after metabolic therapy. Conclusion. Intestinal permeability correlates with the disease severity in patients with NAFLD. Moreover, intestinal permeability may have value for predicting the efficacy of metabolic therapy for NAFLD patients.
Anticoagulation Control in Older Atrial Fibrillation Patients Receiving Vitamin K Antagonist Therapy for Stroke Prevention
Authors: Zulkifly Hanis , Lip Gregory Y. H. , Lane Deirdre A. 
Published: February 2022

Introduction. Efficacy and safety of vitamin K antagonists (VKAs) among atrial fibrillation (AF) patients are enhanced when the International Normalised Ratio (INR) is 2.0–3.0. Anticoagulation control among older patients is perceived to be lower and contributes to poorer initiation and uptake. Objective. To examine the quality of INR control, adverse clinical outcomes, and factors associated with bleeding in older AF patients (≥80 years). Methods. Anticoagulation control assessed by time in therapeutic range (TTR) (Rosendaal method) and percentage INRs in range (PINRR). Among the 205 patients aged ≥80 years, 58.5% were female, with mean (SD) CHA2DS2-VASc 4.4 (1.3) and HAS-BLED 1.8 (0.8) scores. Results. Mean (SD) TTR and PINRR were similar for those aged ≥80 vs. <80 years (66.7 (13.8) vs. 66.7 (13.1)) despite significantly lower INR monitoring intensity (51.2 (22.7) vs. 60.7 (25.8)) and shorter follow-up (4.4 (2.6–6.2) vs. 5.7 years (3.3–7.1)) in those ≥80 years of age. Good anticoagulation control (TTR and PINRR ≥70%) of 44% was seen in both age groups. No significant differences in composite major adverse clinical events were evident for those aged ≥80 vs. <80 years (

p

= 0.55). Cox regression analysis confirmed that age ≥80 years was associated with higher risk of bleeding (HR 1.90 (1.01–3.56);

p

= 0.047). Conclusions. Suboptimal (TTR and PINRR <70%) anticoagulation control was evident in all patients. Risk of bleeding increased, but there was no difference in thromboembolic events and all-cause mortality in those aged ≥80 years. Improving TTR to ≥70% and enhancing anticoagulation monitoring of VKA use remain a clinical priority to prevent bleeding complications, particularly among those aged 80 years and above.
Impact of BMI on Long-Term Outcomes in Patients with ST-Segment Elevation Myocardial Infarction after Primary Percutaneous Coronary Intervention
Authors: Wang Jinwen , Wang Changhua , Zeng Zhechun , Zuo Huijuan 
Published: February 2022

Aim. Obesity paradox remains a point of debate in ST-segment elevation myocardial infarction (STEMI) patients. The aim of this study was to examine the relationship between body mass index (BMI) and clinical outcomes in STEMI patients undergoing primary percutaneous coronary intervention (PPCI). Methods. Outcomes were assessed in 1429 STEMI patients undergoing PPCI between January 2009 and January 2010 in Beijing. Patients were classified into 6 groups according to age (the younger and elderly groups consisting of patients ≤65 and > 65 years old) and baseline BMI (normal weight, BMI < 24 kg/m2; overweight, 24 kg/m2 ≤BMI < 28 kg/m2; obese, BMI ≥ 28 kg/m2). The primary outcome was death, acute myocardial infarction (AMI), or revascularization. Results. On long-term follow-up (mean follow-up of 59 months), 13.9% of patients experienced the adverse event. Multivariate logistic regression analyses showed that low BMI was a significant predictor of the primary outcome only in the younger group. The odds ratio for overweight in comparison with normal weight was 0.741 (95% CI: 0.413–0.979;

p

= 0.038), the odds radio for obesity in comparison with normal-weight patients was 0.508 (95% CI: 0.344–0.750;

p

= 0.016) in the younger group. In the elderly group, diabetes, hypertension, triple disease, regular exercise, angiotensin-converting enzyme inhibitor (ACEI) or angiotensin II receptor blockers (ARBs) use after discharge, and bleeding complication were associated with primary outcome. Conclusion. The obesity paradox was recognized only in the younger age group in STEMI patients undergoing PPCI.
Clinical Effect of Laparoscopic Radical Surgery Combined with Neoadjuvant Chemotherapy in Treating Cervical Cancer and Its Influence on Postoperative Complications and Adverse Reaction Rates
Authors: Gong Wenduan , Liu Yejun 
Published: February 2022

Background. Cervical cancer, the only gynecological malignancy for which a clear pathogeny has been established, has an incidence rate only second to breast cancer. Objective. In our study, we aim to investigate the clinical effect of laparoscopic radical surgery combined with neoadjuvant chemotherapy in treating cervical cancer and its influence on postoperative complications and adverse reaction rates. Methods. Cervical cancer patients admitted to our hospital from August 2018 to May 2020 were retrospectively analyzed as the research object and divided into the control group and the experimental group by the draw method, with 50 cases in each group. The laparoscopic radical surgery was performed on the control group, and the laparoscopic radical surgery combined with neoadjuvant chemotherapy was performed on the experimental group to compare their effective rates, adverse reaction rates, postoperative complication rates, expression levels of serum tumor necrosis factor-α (TNF-α) and soluble interleukin-2 receptor (SIL-2R) inside the body before surgery and at one week after surgery, quality of life (QLI) scores, and Mental Status Scale in Nonpsychiatric Settings (MSSNS) scores. Results. Compared with the control group, the experimental group obtained significantly higher effective rate and QLI scores (

P

< 0.05) and significantly lower adverse reaction rates, postoperative complication rates, expression levels of serum TNF-α and SIL-2R inside the body at one week after surgery, and MSSNS scores (

P

< 0.05), with statistical differences; before surgery, the TNF-α and SIL-2R expression levels of the two groups were not significantly different (

P

> 0.05), but the levels at one week after surgery were significantly lower than those before, indicating statistical significance (

P

< 0.05). Conclusion. The clinical effect of laparoscopic radical surgery combined with neoadjuvant chemotherapy can obviously improve the effective rate of cervical cancer patients and lower the incidence rates of postoperative complications and adverse reactions.
A new species of Leptophoxoides Barnard, 1962 (Amphipoda, Phoxocephalidae) from the Brazilian northeastern continental slope
Authors: Andrade Luiz Felipe , Souza-Filho Jesser Fidelis , Senna André Resende 
Published: February 2022

A new species of Leptophoxoides Barnard, 1962 is described with material from the continental slope of Rio Grande do Norte state, northeastern Brazil at three different depths: 150, 400 and 2,500 meters. Leptophoxoides longisetae sp. nov. can be diagnosed and distinguished from the other two species of the genus, L. molaris Barnard, 1962 and L. marina Senna, 2010, by the following characters: antenna 1 peduncular article 1 ventral apex weakly ensiform; maxilla 1 inner plate longer than outer; maxilliped palp article 3 with blunt and extremely protuberant apex; gnathopods 1-2 carpus almost cryptic; gnathopod 2 palm defined by a large and sharply produced palmar hump; pereopod 6 basis posterodistal corner produced as a blunt lobe; and telson with two dorsal long plumose setae on each side. This is the first record of the genus for northeastern Brazilian waters, uncovering a higher biodiversity in deep waters.
Bycatch of Asteroidea from shrimp trawl fishery in the southwestern Atlantic Ocean – Brazil
Authors: Paula Meriane dos Santos , Freitas Roberta , Ribeiro Rannyele Passos , Barboza Carlos Alberto de Moura , Ruta Christine 
Published: February 2022

Shrimp trawling is considered a significant negative impact on the marine ecosystem, especially on the benthic community. Sea stars (Echinodermata: Asteroidea) are one of the most affected groups by unintentional catches. This study was performed at the Santana Archipelago, a Marine Protected Area in the northern region of Rio de Janeiro State, between 2008-2009. Sea stars accidentally caught by trawling were collected during open and closed season of the shrimp fisheries (Xiphopenaeus kroyeri) at depths of 5-60 m. A generalized linear zero-inflated model was applied to test for differences in capture between fishing seasons and depths. A total of 158 sea star specimens were captured. These specimens were identified as Asterina stellifera, Astropecten acutiradiatus, Astropecten brasiliensis, Astropecten cingulatus, Luidia alternata alternata, Luidia clathrata, Luidia ludwigi scotti, Luidia senegalensis. The sea stars A. brasiliensis and L. senegalensis are currently considered as vulnerable species in the Brazilian official list of threatened species. The higher capture of sea stars was shown in deepest areas, and there was no significant difference in the number of specimens between seasons. This is the first study about asteroids accidentally captured by shrimp trawling.
Claude Lefort y los regímenes de la política en las Américas
Authors: Plot Martín 
Published: February 2022

Since the transitions to democracy of the eighties, two trends of post-Marxist thought had dominated the debates in the region. On the one hand, that of a reading of Gramsci that was split between a more conventional, social-democratic version and a poststructuralist, self-proclaimed radical one. On the other hand, there was also a quite influential trend: a phenomenological one that relied on the anti-totalitarian theorizations of authors such as Hannah Arendt and Claude Lefort. The fellow travelling of these two parallel theoretical and political projects came to an end, however, with the Schmittian turn given by some of the authors associated to the label of radical democracy. This paper will conclude with a critique of this “turn”. Before that, however, a summary and reformulation of Claude Lefort’s notions of forms of society and regimes will be offered as a general framework for the reconsideration of these debates.
Revolução democrática e o momento Lefortiano da democracia brasileira
Authors: Guimarães Juarez 
Published: February 2022

Em primeiro lugar, reexaminaremos criticamente a partir de conquistas recentes da interpretação da obra de Marx, a leitura que Lefort fez obra marxiana e do marxismo6. Em seguida, e na mesma direção, faremos uma releitura da crítica e do diálogo não desenvolvido na obra de Lefort com o pensamento de Gramsci, que buscou, como ele, a reflexão com Maquiavel para renovar o marxismo. Por fim, em um momento mais praxiológico, interpretaremos o momento dramático vivido pela democracia brasileira através do conceito de revolução democrático, inscrevendo a obra de Lefort na própria cena da conjuntura brasileira.
Refugiados: as desigualdades entre os desiguais
Authors: Pasquato Josefina 
Published: February 2022

A definição de “pessoa refugiada” passa por transformações, depende do momento histórico, de motivações políticas e do contexto social e histórico. Esse tema demanda maior atenção de Estados e governos, bem como de quem se dedica à formulação de políticas públicas. O presente artigo aborda a literatura sobre a situação de pessoas em situação de refúgio, de modo geral e no Brasil. Ao Fazê-lo, destaca três categorias especiais entre eles: apatridas, migrantes ilegais e gênero, se subdividindo em mulheres e LGBTI.
Olhares de Profissionais da Defensoria Pública do Estado de São Paulo: análise das demandas e da atuação com a população em situação de rua
Authors: Neves Arthur , Euzébios Filho Antonio 
Published: February 2022

A proposta da realização de pesquisa foi pensada em parceria com o Núcleo Especializado em Cidadania e Direitos Humanos da Defensoria Pública do Estado de São Paulo, sendo fruto de uma parceria recente articulada com o serviço de triagem da Defensoria Pública voltada para atendimento da população em situação de rua. Se propõe, nesse sentido, na realização de entrevistas com profissionais do Centro de Atenção Multidisciplinar (CAM) da Divisão de Atendimento Inicial Especializado (DAI) para sistematização dos desafios e possibilidades dos psicólogos e assistentes sociais do referido serviço de triagem nos seguintes aspectos: (1) no contato com a população atendida; (2) nas demandas recebidas pela defensoria pública das pessoas em situação de rua; (3) no contato com a rede de apoio (4) na articulação em rede. Nesse sentido, o objetivo desta pesquisa é sistematizar, a partir do olhar de psicólogos e assistentes sociais do CAM, as demandas e as necessidades primárias e secundárias da população atendida, os principais desafios de atuação em rede intersetorial e as recomendações destes profissionais ao andamento e execução das políticas públicas, especialmente em relação às diretrizes da Política Nacional de Saúde Mental e dos serviços especializados à população em situação de rua. Diante do conteúdo exposto nas entrevistas e de sua análise, foi observado que apesar da boa relação entre as profissionais e a população em situação de rua que procuram o serviço, dificilmente o trabalho se direciona para uma mudança real de perspectiva dos usuários, se realiza mais enquanto solução de demandas pontuais. Fato que decorre, principalmente, da disparidade entre as demandas que chegam e os recursos disponíveis à atendê-las, tanto na Defensoria pública em si quanto na articulação em rede com outros serviços.
Concurrently Low Coronary Flow Reserve and Low Index of Microvascular Resistance Are Associated With Elevated Resting Coronary Flow in Patients With Chest Pain and Nonobstructive Coronary Arteries
Authors: Nardone Massimo , McCarthy Mary , Ardern Chris I. , Nield Lynne E. , Toleva Olga , Cantor Warren J. , Miner Steven E.S. 
Published: February 2022

Background:
Coronary microvascular function can be distinctly quantified using the coronary flow reserve (CFR) and index of microvascular resistance (IMR). Patients with low CFR can present with low or high IMR, although the prevalence and clinical characteristics of these patient groups remain unclear.

Methods:
One hundred ninety-nine patients underwent coronary microvascular assessments using coronary thermodilution techniques. A pressure-temperature sensor-tipped guidewire measured proximal and distal coronary pressure, whereas the inverse of the mean transit time to room temperature saline was used to measure coronary blood flow. The CFR and IMR were quantified during adenosine and acetylcholine hyperemia.

Results:

Low adenosine and acetylcholine CFR was observed in 70 and 49 patients, respectively, whereas low CFR/low IMR to adenosine and acetylcholine was observed in 39(56%) and 19(39%) patients, respectively. Despite similar adenosine CFR, patients with low CFR/low IMR had increased resting (2.8±1.2 versus 1.3±0.4s
-1
) and hyperemic coronary blood flow (4.8±1.5 versus 2.1±0.5s
-1
) compared with patients with low CFR/high IMR (both
P
<0.01). The same pattern was observed in response to acetylcholine. Patients with low CFR/low IMR to adenosine were younger (56±12 versus 63±10 years), women (84% versus 66%), had fewer coronary risk factors (1.1±1.0 versus 1.6±1.1), lower hemoglobin A1c (5.8±0.7 versus 6.1±0.9 mmol/L), and thinner septal thickness (8.5±2.5 versus 9.9±1.6 mm) compared with patients with low CFR/high IMR to adenosine (all
P
<0.05).

Conclusions:
Low CFR/low IMR to adenosine and acetylcholine are associated with elevated resting coronary blood flow and preserved hyperemic coronary blood flow. These patients present with distinct phenotypic characteristics. Simultaneous CFR and IMR measures appear necessary to differentiate these endotypes.
Territorial behaviour and conflict management in a semi-social cichlid fish, Neolamprologus caudopunctatus
Authors: Schaedelin F.C. , Cunha-Saraiva F. , Faltin C. , Wagner E. , Balshine S. 
Published: February 2022

Abstract
Conflict solving strategies can prevent fights from escalating and reduce the costs of aggressive encounters. Having the capacity to efficiently assess an opponent’s fighting abilities before fully committing to a fight is a useful social skill. Here, we conducted two experiments to investigate how a colony living, cichlid species, Neolamprologus caudopunctatus, changes its aggressive behaviour when faced with familiar vs unfamiliar opponents. First, we staged size matched, same-sex, dyadic resource contests and found that fights were always of low-intensity with neither familiarity nor sex influencing how quickly the conflict ended. Second, we explored the dual defence of mated territorial pairs together defending their territory boundaries against other pairs, either familiar or unfamiliar ones, and discovered that fights between two pairs were more vigorous, and that unfamiliar neighbouring pairs were attacked significantly more often than familiar pairs. We also observed that dark bars sometimes appeared on the sides of contestant’s bodies, and that these bars were far more common in winners than in losers, suggesting that these might be visual signals of dominance. However, conflicts where contestants displayed bars were of longer duration than those without. Taken together, our results further advance our understanding of territoriality and conflict resolution strategies and set the stage for future studies focusing on how animals manage to co-exist in closely aggregated breeding territories and to form colonies.