bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physiotherapeutic evaluation of patients with post COVID-19 condition: current use of measuring instruments by physiotherapists working in Austria and South Tyrol
Authors: Spiegl Claudia , Schiefermeier-Mach Natalia , Schifferegger Erika , Wiederin Claudia , Scheiber Barbara 
Published: September 2022

Abstract
Background
The implementation of standardized assessments in physiotherapeutic practice strongly supports diagnostic and treatment plans. Previous studies reported insufficient usage of standardized assessments due to lack of time, lack of knowledge, lack of resources and other barriers. Physiotherapy in outpatient settings became essential for the rehabilitation of patients with post COVID-19 condition but it remains unknown to what extent assessments are implemented into the evaluation of these patients. In this study, we explored the current use and barriers regarding the implementation of physiotherapeutic assessments to evaluate patients with post COVID-19 condition.

Methods
A cross-sectional online survey was carried out among 180 physiotherapists working in outpatient settings in Austria and South Tyrol.

Results
The majority of physiotherapists (88%) indicated that standardized assessments are useful, though less than a fifth of participants actually implement assessments in practice. Among implementation barriers, “insufficient experience” (41.8%) and “lack of knowledge” (36.6%) were mentioned most often. Concerning specific post COVID-19 assessments, the evaluation of “physical and respiratory function”, “quality of life” and “activities of daily living” were stated to be of particular relevance.

Conclusions
Our study revealed a low implementation rate and identified the main barriers regarding the non-usage of standardized assessments for post COVID-19 patients.

Trial registration
The Private University for Health Sciences and Health Technology (UMIT TIROL), and the Research Committee for Scientific Ethical Questions granted approval for the survey (RCSEQ, Hall in Tirol, Austria, Number 2834).
Anesthetic management in a patient with severe tracheal stenosis by monitoring oxygen reserve index
Authors: Matsuba Sho , Sawai Mitsuki , Higashitani Saki , Sawasaki Fumiya , Kida Hiromasa , Takahashi Kan 
Published: September 2022

Abstract
Background
General anesthesia for tracheal stenting is challenging because of difficult ventilation and accompanying hypoxia. We report the use of oxygen reserve index (ORi™) during tracheal stenting.

Case presentation
Cauterization of an intratracheal tumor and tracheal stenting was scheduled in a patient. ORi decreased from 0.3 to 0.2 after starting cauterization using a flexible bronchoscope through a tracheal tube with 28% oxygen, while SpO2 was maintained at 100%. ORi further decreased to 0, followed by a decrease of SpO2 < 90%, and surgery was interrupted. SpO2 was increased shortly after increasing FiO2 to 1.0, but ORi remained 0 when surgery was resumed; it was increased after completion of cauterization. Both ORi and SpO2 were maintained above 0.4 and 98%, respectively, during tracheal stenting through a rigid bronchoscope under intrapulmonary percussive ventilation.

Conclusion
ORi was useful for predicting a decrease of SpO2 under general anesthesia for tracheal stenting.
The relationship between coping strategies and life quality in major depressed patients
Authors: Bianca Crecan-Suciu D. , Ramona Păunescu L. , Ioana Micluţia V. 
Published: September 2022

Abstract
Background
The present study aimed to explore, for a better understanding, the relationship between dysfunctional coping mechanisms, functionality, and quality of life in patients with major depression, during an acute episode and euthymic phase. 65 patients diagnosed with recurrent major depressive disorder were included in a longitudinal study, during which they were evaluated twice, clinically, for coping mechanisms, and also for different life quality areas. For the first time, all patients were assessed during an acute depressive episode and for the second time after 6 months of euthymia. Coping mechanisms were assessed with the Brief COPE scale, the severity of depression was evaluated by the Hamilton Depression Rating Scale-17 items, the quality of life with the WHOQOL-Bref, and the functionality with GAF.

Results
The coping mechanisms, represented by self-distraction and self-blame, were identified as being significantly correlated with the areas of life quality, mental health, and general environment, for patients having an acute depressive episode. In the euthymic phase of major depression, all dysfunctional coping strategies showed statistically significant associations with the quality-of-life domains and the coping mechanism represented by disengagement was significantly correlated with the global functionality.

Conclusions
Regardless of the current mood state, acute depression or euthymic phase, the dysfunctional coping mechanisms influence the level of life quality domains.
Effect of Ado-Trastuzumab Emtansine on Autologous Platelet Kinetics and Function
Authors: Ansary Ali M. , Stolla Moritz , Corson Jill , Cundy Arianne , Bailey S. Lawrence , Pellham Esther , Bawcom-Randall Morgan , Slichter Sherrill J. , Gadi Vijayakrishna K. 
Published: September 2022

PURPOSE Ado-trastuzumab emtansine (T-DM1) treatment results in grade 3-4 thrombocytopenia in 8%-13% of patients. Prior in vitro studies reported T-DM1 inhibition of megakaryocyte maturation as the cause of decreased platelet production. The current observational study was initiated to evaluate causes of thrombocytopenia in patients with metastatic breast cancer. MATERIALS AND METHODS Patients with human epidermal growth factor receptor 2–positive metastatic breast cancer (N = 11) were enrolled in this postmarket safety study. 111-Indium- radiolabeled autologous platelet recoveries and survivals as well as serial platelet counts, bleeding time assays, and platelet aggregation responses to a wide range of agonists were performed at baseline (BL) and during two consecutive cycles of the drug (3.6 mg/kg IV once every 3 weeks). RESULTS Platelet nadirs occurred earlier in cycle 2 than in cycle 1. Average nadir counts (% BL) in cycles 1 and 2 were 116,000/µL (53% ± 6%) and 115,000/µL (51% ± 9%), respectively, with return to BL by D15 in both cycles. BL platelet survival averaged 8.8 (± 0.3) days but progressively shortened to 5.5 (± 0.5) days during cycle 1 and to 4.6 (± 0.3) days during cycle 2 ( P < .001 compared with BL for both cycles). Aggregation responses to all agonists decreased during the study, both in cycle 1 and cycle 2. CONCLUSION Following T-DM1 administration, we observed statistically significant progressive decreases in platelet survivals and decreased platelet function from BL values. In distinction to published in vitro studies, these unexpected results indicate a direct toxic effect of T-DM1 on patients' autologous circulating platelets.
An audit of sharps injuries in clinical skills simulation wards at a UK university
Authors: Hambridge Kevin , Endacott Ruth , Nichols Andrew 
Published: September 2022

Background/Aims Healthcare students are at high risk of sharps injuries, which can negatively impact their confidence and wellbeing. This study audited three clinical skills simulation wards at a UK university to determine the incidence of sharps injuries in this educational setting. Methods An audit of sharps injuries sustained in three clinical skills simulation wards was conducted, including data from 2008–2016. The authors developed an audit tool to collect data on the number of incidents that occurred, the type of individual involved and the nature of the incident. Results were analysed to compare the incidence of general injuries and sharps injuries among healthcare students and staff. Results A total of 46 incidents were recorded across the three wards during the 8-year period. Sharps injuries were by far the most common type of injury, comprising 69.6% of recorded incidents, followed by fainting at 19.6%. The highest proportion of general injuries (56.5%) and sharps injuries (59.4%) occurred among nursing students. However, the association between incidents and type of individual involved was not statistically significant Conclusions Sharps injuries were the most common type of incident in the clinical skills simulation wards, with student nurses being at highest risk. Intervention is needed to improve safety in this educational setting, including sharps handling training, with greater focus on existing regulations.
Interceptive management of increased overjet in young children: a clinical protocol
Authors: Smyth Robert SD , Patel Khushbu , Ashley Paul , Noar Joseph H 
Published: September 2022

This article describes the different techniques for the management of an increased overjet in a child considered too young for conventional orthodontics, as well as the clinical situations in which these techniques may be useful. This is particularly aimed at general dental practitioners and paediatric dentists working in areas with limited access to specialist orthodontic services. CPD/Clinical Relevance: Knowledge of techniques for early management of an increased overjet in young children is of interest.
Monkeypox and the dental team
Authors: Samaranayake Lakshman , Anil Sukumaran 
Published: September 2022

Monkeypox (MPX), a rare zoonotic disease, endemic to some African countries is now spreading in non-endemic regions, including the UK. So far, it has been reported in 93 countries with over 38,000 global cases, although the signs are that the disease may be plateauing in UK. The outbreak was declared a public health emergency of international concern by the World Health Organization (WHO). Monkeypox virus (MPXV), belongs to the family Orthopoxviridae, the same family as the smallpox (variola) virus. Although some features of MPX resemble smallpox, a disease that has been eradicated, the former is far milder with a very few associated fatalities. Usually, the initial signs of MPX appear during its prodrome, as single or multiple macular lesions on the oral mucosa, accompanied by generalized lymphadenopathy, followed by the characteristic macular, papular vesicular rash on the skin that heals with scarring. The major mode of spread of MPX is generally through direct or indirect contact with body fluids or lesion material. Its transmission in the dental clinic environment is unlikely if the standard infection prevention and control (IPC) precautions recommended in the National IPC Manual (NHS England) are adhered to. These include wearing N95 masks, fluid-resistant attire and eye protection. Here, the virology, clinical manifestations, diagnosis, management and prevention strategies of MPX, with particular reference to dentistry are reviewed. CPD/Clinical Relevance: To describe the epidemiology of the re-emergent monkeypox outbreak, and discuss the management of dental patients who may present with it.
Perceptions and attitudes of ICU physicians toward antibiotics prescribing and resistance: A cross-sectional study
Authors: Shendy Esraa Mahrous , Elberry Ahmed A. , Hamed Mohamed Lamia , Boshra Marian S. 
Published: September 2022

Background and aim
Antibiotic resistance is a major emphasis in intensive care units (ICUs). Better understanding of ICU physicians’ perceptions, attitudes, and knowledge about antimicrobial prescribing practices could facilitate more effective interventions in fighting antimicrobial resistance in Egyptian ICUs and establishing a proper Antimicrobial Stewardship Program.

Methods
A cross-sectional questionnaire study was conducted including 92 physicians distributed across the different types of Egyptian healthcare institutions in two cities of Egypt; Cairo and El Monufia. Over a period of three months, started in December 2019 and ended in February 2020.

Results
A total of 92 Egyptian physicians were included in the study. Seventy (76.1%) of the surveyed physician strongly agreed and 22 (23.9%) agreed that antibiotic resistance is a worldwide problem. Moreover, 50 (54.3%) strongly agreed and 40 (43.4%) agreed that it is a problem in their hospitals while only 2 (2.1%) disagreed. Poor hand hygiene (67.5%), poor infection control practices by healthcare professionals (63.9%) as well as wrong practices in the management of invasive devices (68.7%), and poor environmental cleaning practices (63.4%) were considered very important causes of AMR by the majority of the surveyed ICU physicians. Almost all of the physicians (95%) rated an advice from a clinical pharmacist as very or moderately helpful intervention, while (52%) declared an advice from a microbiologist or an infectious disease specialist as very helpful.

Conclusion
The results of the present study showed that the Egyptian ICU physicians have remarkable knowledge regarding antibiotic resistance as a worldwide problem and a high sensibility toward the problem in their hospitals. The study also showed that implementation of proper AMS is an urgent need as physicians answers for the different questions in the survey showed that their attitudes and perceptions regarding antibiotic resistance and their way in prescription could be modified and improved if AMS programs with suitable training programs and local guidelines are provided among different types of Egyptian hospitals.
Anticipated stigma and associated factors among chronic illness patients in Amhara Region Referral Hospitals, Ethiopia: A multicenter cross-sectional study
Authors: Salih Mohammed Hassen , Mekonnen Hussen , Derseh Lema , Lindgren Helena , Erlandsson Kerstin 
Published: September 2022

Background
Anticipated stigma related to chronic illness patients undermines diagnosis, treatment, and successful health outcomes. The study aimed to assess the magnitude and factors associated with anticipated stigma among patients with chronic illness attending follow-up clinics in Amhara Region Referral Hospitals, Ethiopia.

Methods
A cross-sectional institution-based study was conducted in Amhara Region Referral Hospitals from 01 March to 15 April 2021. A simple random sampling technique was used to select the three Referral Hospitals in the region and study subjects. Data were collected using a pre-tested interview-based questionnaire. Data were entered and cleaned with Epi-Info version 6 and exported for analysis STATA version 14. Multiple linear regression was used to show the association between anticipated stigma and potential factors. Associations were measured using ß coefficients and were considered statistically significant if the p-value > 0.05.

Results
A total of 779 patients were included for analysis with a response rate of 97%. Their mean (Standard deviation) of anticipated stigma was estimated at 1.86 and 0.5, respectively. After running an assumption test for multiple linear regression; educational status, cigarette smoking, psychological distress, medication adherence, alcohol consumption, and social part of the quality of life were statically significantly associated with anticipated stigma.

Conclusion and recommendation
The result showed a high level of anticipated stigma reported among the participants. Emphasizing improving their social part of the quality of life, avoiding risky behaviors like alcohol consumption and cigarette smoking, access to health education for chronically ill patients, integrating mental health in all types of chronic disease, and developing strategies and protocols which will help to improve patient medication adherence to their prescribed medication will be crucial. This can provide a foundation for government andnon-governmental organizations, and researchers implementing evidence-based interventions and strategies on chronic care to address factors related to anticipated stigma.
The associations of BMI, chronic conditions and lifestyle factors with insomnia symptoms among older adults in India
Authors: Muhammad T. , Gharge Shivani , Meher Trupti 
Published: September 2022

Background
The aim of the study was to estimate the prevalence of insomnia symptoms and to examine the associations of body mass index (BMI), chronic diseases, and lifestyle factors with self-reported insomnia symptoms among older people in India.

Methods
We conducted a cross-sectional study using data from the baseline wave of the Longitudinal Ageing Study in India (LASI) that was collected during 2017–18. A sample of 31,358 older adults aged 60 and above was included in the analyses. Descriptive statistics and bivariate and multivariable analyses were performed to obtain the results.

Results
In this study, insomnia symptoms were reported by around 36 percent of older adults aged 60 and above. After controlling for socio-demographic factors, insomnia symptoms were positively associated with the risk of being underweight [AOR: 1.289, CI: 1.211–1.372] and negatively associated with obesity/overweight [AOR: 0.928, CI: 0.872–0.990] as compared to older adults with normal BMI. The odds of insomnia symptoms were higher among those who reported the following chronic conditions, i.e., hypertension [AOR:1.356, CI:1.278–1.438], diabetes [AOR:1.160, CI:1.074–1.254], chronic lung diseases [AOR:1.485, CI:1.351–1.632], bone-related diseases [AOR:1.561, CI:1.458–1.670] and any psychiatric disorders [AOR:1.761, CI:1.495–2.074]. In addition, older adults who were physically active [AOR: 0.850, CI:0.804–0.900] were less likely to report insomnia symptoms.

Conclusions
The study suggests a high prevalence of insomnia symptoms among the older population in India. Early identification of the signs of insomnia in older population is crucial, as is timely treatment for any kind of sleep problems. In addition, nutrition-based interventions and individual disease-specific management programs may help minimize the stressful situations in later life and develop a good night’s sleep for the older population.
Androgenic status in men during COVID-19
Authors: Rozhivanov R. V. , Melnichenko G. A. , Andreeva E. N. , Mokrysheva N. G. 
Published: September 2022

BACKGROUND. COVID-19 is a disease that has a negative systemic effect on the human body, including the male gonads. Therefore, the androgenic status in men with COVID-19 needs to be studied.AIM. To evaluate the levels of total testosterone, sex hormone binding globulin (SHBG) and free testosterone in men in the acute phase of COVID-19 and during convalescence.MATERIALS AND METHODS. A continuous dynamic prospective study of 70 men with moderate to severe COVID-19 at the age of 50[44; 64] years. During the study, the levels of total testosterone, SHBG were determined with further calculation of the level of free testosterone by Vermeullen. The data were collected twice — at the patient’s hospitalization and at his discharge. The differences between the groups were considered statistically significant at p <0.05.RESULTS. At the time of hospitalization for COVID-19, hypogonadism syndrome was observed in 61 people — 87%. Patients with hypogonadism did not statistically significant differ in age and severity of COVID-19 disease compared to men without hypogonadism. Inpatient treatment lasting 12[10;14] days resulted in a statistically significant increase in the levels of total testosterone from 4,7[2,96;8,48] to 12,85[8,62;19,2] nmol/l, p<0,001; SHBG from 27,87[20,78;36,57] to 33,76[26,27;52,60] nmol/l, p<0,001 and free testosterone from 107[65;174] to 235[162;337] pmol/l, p<0,001. This led to the elimination of hypogonadism in 28 patients — 40%. Patients with persistent hypogonadism were statistically significantly older than men with normalized testosterone, there were no statistically significant differences in the initial levels of total testosterone, SHBG and free testosterone, and there were also no differences in the prevalence of severe COVID-19 (3,97[2,86;7,46] vs 4,26[2,93;5,96] nmol/l, p=0,100; 28,76[20,78;48,59] vs 24,63[18,85;31,70] nmol/l, р=0,994; 100[58;118] vs 96[64;143] pmol/l, p=0,522; 24 против 18%, p=0,754, respectively).CONCLUSION. COVID-19 has a pronounced negative effect on the production of testosterone in men, leading to the development of laboratoric hypogonadism, which is potentially reversible. The reversibility of laboratoric hypogonadism is typical for younger patients.
O imaginário sobre a importância da língua inglesa na escola pública
Authors: Aiub Giovani Forgiarini 
Published: September 2022

A aprendizagem de línguas estrangeiras em escolas da rede pública, em especial a língua inglesa, se caracteriza principalmente pela sua alta taxa de insucesso. Além disso, o ensino destas outras línguas, como vem sendo concebido nos dias de hoje, tem uma base estritamente linguística, supondo a língua homogênea e transparente, e o sujeito como centrado, idealizado e dono de seu dizer. Este trabalho, filiado à Teoria da Análise do Discurso de vertente francesa, busca saber quais são os discursos que circulam sobre a importância de ensinar e de aprender inglês neste contexto, busca saber qual o imaginário do professor e do aluno sobre a relevância da língua inglesa. Busca saber também qual imagem que eles têm sobre este referente. Para tanto, foram questionados professores e alunos do ensino fundamental e médio que já tenham passado pela experiência de (tentar) ensinar e (tentar) aprender esta outra língua.
Electrophysiological responses of Varroa mite to honey bee drone brood volatiles
Authors: Teski Anna , Bozsik Gábor , Brunner Sándor , Szőcs Gábor 
Published: September 2022

AbstractVarroa mite, Varroa destructor is the most important ectoparasite of the honey bee, Apis mellifera worldwide, contributing to colony collapse. The development of alternative non-toxic methods against this pest is needed, as most of the wide-used acaricides in apiculture are banned in the European Union, which increase the risk of developing resistant mite populations against the remaining few products. In order to reveal biological basis of a new, semiochemical-based method, the aim of this study was to search for olfactory stimuli, used by female Varroa mites in orienting to drone brood for egglaying. Volatiles of uncapped drone brood were collected in situ, inside bee-hives, using either charcoal, or HayeSep® Q filters. Collections were analyzed by gas chromatograph linked to an electrotarsogram detector (GC-ETD), using the foreleg of female mite. Results showed that most components were present in collections trapped by any of these filters. However, some components appreared only in charcoal-, while others only in HayeSep® collections, respectively. Out of the large number of components, a few elicited electrophysiological responses. Structure elucidation of these active components are underways. Futher behavioral studies should reveal, which components play role in attraction of Varroa mites.
New data to the scale insect (Hemiptera, Coccomorpha) fauna of Spain
Authors: Szita Éva , Blay Goicoechea Maria Amparo , París Mercedes , Kaydan Mehmet Bora 
Published: September 2022

AbstractNew data are provided on the distribution of scale insect species based on the soil sample collection of Museo Nacional de Ciencias Naturales, Madrid, Spain. Six species proved to be new to the scale insect fauna of Spain: 1 species of Ortheziidae (Ortheziola vejdovskyi Sulc), 3 species of Pseudococcidae (Fonscolombia graminis Lichtenstein, Peliococcus mathisi (Balachowsky), Rhodania porifera Goux) and 2 species of Rhizoecidae (Rhizoecus arabicus Hambleton, Ripersiella lelloi (Mazzeo)).