bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feasibility of Transcutaneous Method for Carbon Dioxide Monitoring in
an Intensive Care Unit
Authors: Boyacı Nazlıhan , Mammadova Sariyya , Naurizbay Nurgül , Güleryüz Merve , İnci Kamil , Gürsel Gül 
Published: January 2022

Background:
Transcutaneous partial pressure of carbon dioxide (PtCO2) monitorization
provides a continuous and non-invasive measurement of partial pressure of carbon dioxide (pCO2).
In addition, peripheral oxygen saturation (SpO2) can also be measured and followed by this
method. However, data regarding the correlation between PtCO2 and arterial pCO2 (PaCO2) measurements
acquired from peripheric arterial blood gas is controversial.

Objective:
We aimed to determine the reliability of PtCO2 with PaCO2 based on its advantages, like
non-invasiveness and continuous applicability.

Methods:
Thirty-five adult patients with hypercapnic respiratory failure admitted to our tertiary
medical intensive care unit (ICU) were included. Then we compared PtCO2 and PaCO2 and both
SpO2 measurements simultaneously. Thirty measurements from the deltoid zone and 26 measurements
from the cheek zone were applied.

Results:
PtCO2 could not be measured from the deltoid region in 5 (14%) patients. SpO2 and pulse
rate could not be detected at 8 (26.7%) of the deltoid zone measurements. Correlation coefficients
between PtCO2 and PaCO2 from deltoid and the cheek region were r: 0,915 and r: 0,946 (p =
0,0001). In comparison with the Bland-Altman test, difference in deltoid measurements was -1,38
± 1,18 mmHg (p = 0.252) and in cheek measurements it was -5,12 ± 0,92 mmHg (p = 0,0001).
There was no statistically significant difference between SpO2 measurements in each region.

Conclusion:
Our results suggest that PtCO2 and SpO2 measurements from the deltoid region are reliable
compared to the arterial blood gas analysis in hypercapnic ICU patients. More randomized
controlled studies investigating the effects of different measurement areas, hemodynamic parameters,
and hemoglobin levels are needed.
Susceptibility to Rhinovirus-induced Early Wheezing as a Risk Factor for
Subsequent Asthma Development
Authors: Mikkola Hannele , Honkila Minna , Tapiainen Terhi , Jartti Tuomas 
Published: January 2022

Abstract:
Rhinovirus is one of the two most common viral agents that cause bronchiolitis in young
children. During the first 12 months, it is second to the respiratory syncytial virus, but after 12
months, it begins dominating the statistics. Wheezing and dry cough are typical clinical symptoms
indicative of rhinovirus-induced bronchiolitis, although overlap of symptoms with other virus infections
is common. Several studies have shown that atopic predisposition and reduced interferon responses
increase susceptibility to rhinovirus-induced wheezing. More recent studies have found
that certain genetic variations at strong asthma loci also increase susceptibility. Rhinovirus-induced
wheezing in the early years of life is known to increase the risk of subsequent asthma development
and may be associated with airway remodeling. This risk is increased by aeroallergen sensitization.
Currently, there are no clinically approved preventive treatments for asthma. However, studies
show promising results indicating that children with rhinovirus-affected first-time wheezing respond
to bronchodilators in terms of less short-term symptoms and that controlling airway inflammatory
responses with anti-inflammatory medication may markedly decrease asthma development.
Also, enhancing resistance to respiratory viruses has been a topic of discussion. Primary and secondary
prevention strategies are being developed with the aim of decreasing the incidence of asthma.
Here, we review the current knowledge on rhinovirus-induced early wheezing as a risk factor
for subsequent asthma development and related asthma-prevention strategies.
Vitamin D and Omega-3 Polyunsaturated Fatty Acids in Type 1 Diabetes Modulation
Authors: Bastos Thais Sibioni Berti , Braga Tárcio Teodoro , Davanso Mariana Rodrigues 
Published: January 2022

Background:Type 1 diabetes (T1D) is a chronic autoimmune disease affecting people globally. Usually developed during childhood, T1D is characterized by the destruction of pancreatic β-cells due to immune cell attack and the establishment of an inflammatory process.Objective:The study aimed to investigate the effects of vitamin D through its nuclear receptor and the ω-3 polyunsaturated fatty acids (PUFAs) through their lipid derivatives in T1D modulation. Both components exert anti-inflammatory activity and act directly on cells of the immune system, attenuating the destruction of insulin-producing cells. Furthermore, they lead to a better glycemic level, reducing the need for insulin and a normal immune state, such as C-peptide maintenance.Method:Presently, our review highlights the significant studies that evaluated the supplementation of vitamin D and ω-3 PUFAs in humans and animal models in the modulation of T1D.Conclusion:The data collected suggests that supplementation can provide potential benefits, mainly when done early in the diagnosis, since it reduces the need for insulin and the risk of complications generated by the disease.
A Mobile App to Increase Fruit and Vegetable Acceptance Among Finnish and Polish Preschoolers: Randomized Trial
Authors: Vepsäläinen Henna , Skaffari Essi , Wojtkowska Katarzyna , Barlińska Julia , Kinnunen Satu , Makkonen Riikka , Heikkilä Maria , Lehtovirta Mikko , Ray Carola , Suhonen Eira , Nevalainen Jaakko , Sajaniemi Nina , Erkkola Maijaliisa 
Published: January 2022

Background
Early childhood education and care (ECEC) centers are ideal venues for food education. As smartphones and tablets are becoming increasingly popular in ECEC centers, technology can be used to deliver such pedagogical content. Evidence suggests that video games can affect fruit and vegetable (FV) consumption among 9- to 12-year-old children, but studies among preschoolers are scarce.

Objective
This paper describes the development of the Mole’s Veggie Adventures app and its effectiveness in increasing FV acceptance among Finnish and Polish preschoolers aged 3 to 6 years.

Methods
A multiprofessional team created an app to be used in ECEC centers in groups of 3 to 10 children. The app aimed to increase vegetable acceptance, and it was built using elements that support the development of self-regulation and social skills. Altogether, 7 Finnish and 4 Polish ECEC centers participated in the study. Before randomization, parents reported background factors and their children’s willingness to taste different FVs. The ECEC professionals in the intervention arm were instructed to use the app at least once a week during the 3- to 4-week intervention period. The main outcomes in this unblinded, cluster-randomized study were FV acceptance and relative FV acceptance. The first was calculated as a sum variable describing the children’s willingness to taste 25 different FVs, the second as FV acceptance divided by the number of FVs served. We used analysis of covariance to compare the FV acceptance and relative FV acceptance scores between the intervention and control groups at follow-up.

Results
A total of 221 children were included in the analysis. At follow-up, the intervention group (115/221, 52%) had higher FV acceptance scores (baseline adjusted difference of mean 7.22; 95% CI 1.41-13.03) than the control group (106/221, 48%). The intervention effect was parallel for relative FV acceptance scores (baseline adjusted difference of mean 0.28; 95% CI 0.05-0.52).

Conclusions
The Mole’s Veggie Adventures app has the potential to increase FV acceptance among preschoolers and can be a valuable tool in supporting food education in ECEC centers. Furthermore, the app can be feasibly incorporated into preschool routines in countries with different educational environments.

Trial Registration
ClinicalTrials.gov NCT05173311; https://tinyurl.com/4vfbh283
Comparison of Some Indicators in Serum and Saliva on Periodontitis
Authors: Yousif Araz M , Ismail Parween A , Ismail Narmeen A , Ismail Namam A 
Published: January 2022

Objectives: To assess the serum indicators level in healthy and periodontitis subjects and correlate the levels in the terms of changes of serum and salivary parameters in periodontal disease. Methods: The assay comprised 85 subjects, enrolled of both genders in the age range of 33-56 years old. Volunteers were categorized into two groups: 40 healthy individual, other groups (periodontal disease) embraced 45 patients. The salivary and blood samples were collected and sent for biochemical analysis to measure the nitric oxide (NO), superoxide dismutase (SOD), glutathione, catalase, Interleukin 6 (IL-6), Interleukin 4 (IL-4), and interferon-Î³ (IFN-Î³) levels in periodontitis patients. Results: Based on the statistical evaluation of bio-indicator parameters, the following conclusion can be shown from this revision: Serum and saliva SOD (P <0.001), glutathione(P <0.001), and catalase(P <0.001) activates were significantly reduced in periodontitis as compared with control groups, the remaining biochemical assessed in periodontitis patients [NO (P <0.001), IL-4 (P <0.0001), IL-6 (P <0.0001), and IFN-Î³ (P <0.0001)] indicated significantly high levels in both serum and saliva samples. Conclusions: The NO, SOD, catalase, glutathione and cytokines may be used as bio-indicator for periodontitis exposure, medical conduct and severity. This recognition offers early diagnosis of disease and progression. Also there was a direct positive correlation between the salivary and the serum bio-markers levels, which it was proved that the salivary non-invasive examination had a significant association with the serum investigation.
EFEKTIVITAS PEMBELAJARAN ONLINE SAAT PANDEMI COVID-19 DI UNIVERSITAS ISLAM NEGERI AR-RANIRY BANDA ACEH
Authors: Muazzinah  , Akhiar  
Published: January 2022

The Covid-19 pandemic has changed the daily routine of work. Since the issuance of PP Number 21 of 2020 concerning Large-Scale Social Restrictions, activities in public places or public facilities have been limited with the aim of reducing the spread of Covid-19. Likewise with the learning process, the Covid-19 pandemic has changed the conventional face-to-face learning pattern to face-to-face online. Therefore, this study aims to determine how effective online learning is at UIN Ar-Raniry Banda Aceh. The research method used in this study is a qualitative method with a descriptive approach with observation, interviews and documentation techniques. The research subjects are LPM UIN Ar-Raniry as policy makers as well as lecturers and students at UIN Ar-Raniry as implementers of online learning. The results of this study indicate that online learning at UIN Ar-Raniry Banda Aceh has not been effective, but to achieve this effectiveness the campus has tried as much as possible by doing several things, namely before the implementation of online learning activities the campus first designed planning and survey conditions and training to lecturers, then formulate policies, formulate goals and strategies, determine facilities and supervision which is carried out routinely through the Siakad portal.
Keywords: Effectiveness, Online Learning, Covid-19 Pandemic
Surgical Robotics Systems for Deep Brain Neurosurgery
Authors: Nassief Andrew M. K. 
Published: January 2022

Robotics systems designed for surgical applications such as
Neurosurgery, likely may need to implement synchronous communication in
real time and asynchronous learning. It will likely primarily be
oriented towards spatial imaging and 3D virtualization, various
communication protocols, and calibration settings in order to perform
optimal results. In regards to computation, it needs to be heavily fault
tolerant in operation. It also needs to be aware of false positives.
Likely a complex deep brain surgical robotics system would implement
variations of brain mapping technology and may utilize
topological neuroanatomy. Various technologies in regards to the mapping
of the brain, visualization, robotics and mechatronics systems would
need to be in place. This paper is to look at the sciences through a
theoretical and conceptual process. This isn’t FDA reviewed for medical
accuracy and is meant to warrant a theoretical paper where information
is “as-is”. This will hopefully provide a bleuprint for continuing
research later on.
BELEZA E MODA DA MULHER REPRESENTADAS NA IMPRENSA FEMININA DOS SÉCULOS XX E XXI
Authors: Nogueira Joani Almeida dos Santos , Silva Daiane Lopes da 
Published: January 2022

Neste artigo, investigamos revistas produzidas entre os séculos XX e XXI e a maneira como as mulheres são representadas. Nosso estudo está voltado para cinco publicações: Jornal das Moças (1914); Revista Feminina (1936); Querida (1968); Capricho (1999); Vogue Brasil (2018). Para a presente análise, temos o entrelaçamento entre duas áreas científicas, História e Linguística que resultaram na História das Ideias Linguísticas. Esse estudo, ainda que fragmentado, pois fizemos um breve recorte de diferentes materiais ao longo de dois séculos, possibilita a verificação e conhecimento historiográfico com o auxílio dessas fontes e demonstra um novo olhar sobre a História, distinta daquela que valorizava apenas figuras heroicas, os grandes feitos por elas e as realizações julgadas como importantes. Desse modo, constatamos o postulado por Chartier (1990, p.16-17), precursor da ideia que defende a maneira “como, em diferentes lugares e momentos, uma determinada realidade social é construída e dada a ler”.

Palavras-chave: Imprensa feminina. Representação. Beleza. Moda.
Analisis Perkembangan Kemampuan Bahasa Anak Kelompok A Taman Kanak-Kanak
Authors: Ita Efrida , Wewe Melkior , Go.o Emirensiana 
Published: January 2022

Penelitian ini berawal dari rendahnya pemahaman pengembangan bahasa anak pada kelompok A Taman Kanak-kanak Negeri Harapan Bangsa. Penelitian ini bertujuan untuk mengetahui: (1) perkembangan kemampuan bahasa anak usia 4-5 tahun yang sesuai dengan Standar Tingkat Pencapaian Perkembangan Anak (STPPA) dan (2) mengetahui perkembangan kemampuan bahasa anak kelompok A Taman Kanak-kanak Negeri Harapan Bangsa Bajawa. Penelitian ini menggunakan rancangan penelitian kualitatif. Pengumpulan data dilakukan melalui wawancara, observasi dan dokumentasi. Informan dalam penelitian ini adalah kepala sekolah dan guru kelompok A, sebanyak 13 orang. Analisis data menggunakan model interaktif dari Miles dan Huberman dengan komponen-komponennya, yaitu pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan. Kesahihan data ditentukan dengan cara triangulasi. Hasil penelitian menunjukkan bahwa perkembangan kemampuan bahasa anak usia 4-5 tahun pada lingkup perkembangan memahami bahasa dan mengenal keaksaraan sudah memenuhi Standar Tingkat Pencapaian Perkembangan anak (STPPA), sedangkan pada lingkup perkembangan mengungkapkan bahasa, anak usia 4-5 tahun masih membutuhkan bimbingan guru. Kemampuan bahasa anak kelompok A Taman Kanak-kanak Negeri Harapan Bangsa Bajawa, Berkembang Sesuai Harapan (BSH). Hasil penelitian ini menunjukan bahwa aspek bahasa sangat penting untuk dikembangkan pada setiap anak yang masih dalam tahap perkembangan. Karena kemampuan bahasa anak sangat berpengaruh pada aspek-aspek perkembangan anak yang lain.
Wai Selabung geothermal reservoir analysis based on gravity method
Authors: Sarkowi Muh , Wibowo Rahmat Catur , Sawitri Regina Febryzha , Mulyanto Bagus Sapto 
Published: January 2022

Research has been conducted using the gravity method in the Wai Selabung area, South Ogan Kemiring Ulu Regency, South Sumatra Province, correlated with geological data, magnetotellurics, and geochemical data. This research aims to get structural patterns, subsurface models and identify the heat source and reservoir areas of the Wai Selabung geothermal system. This study uses the gravity method to model the subsurface, which is correlated with magnetotelluric and geochemical data to identify reservoir prospect areas. The results obtained from this research include residual anomalies in the research area showing the presence of a northwest-southeast trending fault structure by the main fault structure of this area trending northwest-southeast and slightly southwest-northeast. Analysis of the Second Vertical Derivative value of zero indicates the boundaries of the geothermal reservoir in the middle of the research area. The results of the 3D inversion modeling of the research area show that low density (2 to 2.15 g/cm3) indicates the location of the reservoir, medium-density values (2.2 to 2.4 g/cm3) are tertiary sandstone sedimentary. The high-density distribution value (2.5 to 2.9 g/cm3) indicates a potential heat source. And based on the analysis of the gravity method correlated with geological data, magnetotelluric, and geochemical data, the prospect area for the Wai Selabung geothermal reservoir, is around Teluk Agung, Perekan, and Talang Tebat.
Irene Vallejo. El infinito en un junco. La invención de los libros en el mundo antiguo, Grupal, Ciudad Autónoma de Buenos Aires; Siruela, Madrid, 2020, 452 pp., ISBN 9788417860790
Authors: Coria Marcela 
Published: January 2022

Revisión del libro El infinito en un junco. La invención de los libros en el mundo antiguo por I. Vallejo
Nietzsche como educador
Authors: Díaz Genis Andrea , Mélich Sangrá Joan Carles 
Published: January 2022

Resumen: Este artículo interpreta la posición de Nietzsche sobre la educación, a partir de una filosofía que se emparenta con la tradición antigua de la filosofía como forma de vida y arte de existencia. Se elabora a partir de una idea que parte de la singularidad como supuesto a la vez que finalidad. Se analiza la idea de un maestro que quiere discípulos que rompan con él, para finalmente llegar a Nietzsche mismo como maestro de la humanidad. Finalmente, tener a Nietzsche como maestro, es actuar en la posibilidad de la paradoja, es abrirse a multiplicidad de mundos posibles, y no entregar nada a la posesión.
The effect of a ketamine constant rate infusion on cardiovascular variables in sheep anesthetized at the minimum alveolar concentration of sevoflurane that blunts adrenergic responses
Authors: Chang Kevin , Barletta Michele , Messenger Kristen M. , Sakai Daniel M. , Reed Rachel A. , Quandt Jane E. 
Published: January 2022

Abstract

OBJECTIVE
To evaluate the effect of a constant rate infusion of ketamine on cardiac index (CI) in sheep, as estimated using noninvasive cardiac output (NICO) monitoring by partial carbon dioxide rebreathing, when anesthetized with sevoflurane at the previously determined minimum alveolar concentration that blunts adrenergic responses (MACBAR).

ANIMALS
12 healthy Dorset-crossbred adult sheep.

PROCEDURES
Sheep were anesthetized 2 times in a balanced placebo-controlled crossover design. Anesthesia was induced with sevoflurane delivered via a tight-fitting face mask and maintained at MACBAR. Following induction, sheep received either ketamine (1.5 mg/kg IV, followed by a constant rate infusion of 1.5 mg/kg/h) or an equivalent volume of saline (0.9% NaCl) solution (placebo). After an 8-day washout period, each sheep received the alternate treatment. NICO measurements were performed in triplicate 20 minutes after treatment administration and were converted to CI. Blood samples were collected prior to the start of NICO measurements for analysis of ketamine plasma concentrations. The paired t test was used to compare CI values between groups and the ketamine plasma concentrations with those achieved during the previous study.

RESULTS
Mean ± SD CI of the ketamine and placebo treatments were 2.69 ± 0.65 and 2.57 ± 0.53 L/min/m2, respectively. No significant difference was found between the 2 treatments. Mean ketamine plasma concentration achieved prior to the NICO measurement was 1.37 ± 0.58 µg/mL, with no significant difference observed between the current and prior study.

CLINICAL RELEVANCE
Ketamine, at the dose administered, did not significantly increase the CI in sheep when determined by partial carbon dioxide rebreathing.
HAMBATAN DAN SOLUSI PEMBELAJARAN JARAK JAUH PADA ERA PANDEMI COVID-19 DI JAWA TENGAH
Authors: Sofianto Arif , Zuhri Mursid 
Published: January 2022

Abstract: Online learning during the Covid 19 pandemic had implications for the quality of education, on the other hand it led to innovation. The objectives of this study are: 1) To analyze the condition of senior high school in the Covid-19 pandemic era in Central Java (problems and progress); 2) Identifying the readiness of teachers and schools; 3) Identifying the need for quality education; and 4) Analyze the policies needed to improve the quality of education in the era of the Covid-19 pandemic. This research is descriptive, mixed method approach, qualitative and quantitative. This research involving 260 informants (principal, teachers, parents, and students). This study also used a survey method involving 84 principals, 831 teachers, 4,124 parents and 10,048 students. The data collection instruments were questionnaires and FGD. Qualitative analysis uses an interactive model developed by Miles and Huberman, quantitative analysis is descriptive, namely mean and percentage. The conclusions of this study: First, education in the Covid-19 pandemic era with a home learning strategy (daring) faces the problem of lack of facilities and infrastructure, mastery of technology, quota/internet data packages, internet network/signal. The advantages are increased mastery of technology, learning innovation, introduction of new methods, time/ energy/cost efficiency. Second, many teachers were not ready, but schools had also prepared adequate facilities, and encouraged new innovations. Third, what is needed to realize quality education through increasing the capacity of teachers, subsidizing facilities and infrastructure, improving the education system, and learning innovation. Fourth, the policy required is the implementation of a blended learning system, e-learning/LMS, curriculum adjustments, and encouraging innovation.