bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fish-derived Probiotic Improves Growth Performance and Pathogen Resistance of Juvenile Grass Carp (Ctenopharyngodon idella) by Modulating Keystone Taxa and Enhancing Microbial Interactions
Authors: Qi Xiaozhou , Xue Mingyang , Wang Gaoxue , Ling Fei 
Published: December 2022

Abstract
Host-derived probiotics are bacteria isolated from the host's gut to improve the host’s growth and health. With more stringent antibiotic prohibitions in animal production, in-feed probiotics are becoming an appealing alternative to antibiotics in aquaculture. To explore the effects of Pseudomonas monteilii JK-1 on grass carp growth performance and disease resistance, 180 apparently healthy juvenile grass carp (3 ± 0.05 g) were randomly separated into 2 groups, each of which had 3 duplicates and 30 grass carp per replicate. Fish were fed with basal diets (control) or basal diets supplemented with P. monteilii JK-1 (1 × 107 CFU/g diet, PM-JK1) for 8 weeks. Results showed that P. monteilii JK-1 significantly increased the weight gain (WG), specific growth rate (SGR), survival rate and significantly reduced the pathogen load in grass carp (P < 0.05). Moreover, P. monteilii JK-1 supplementation significantly improved the expression of interleukin 1β (IL-1β), interleukin 10 (IL10), tumor necrosis factor alpha (TNF-α), and transforming growth factor beta (TGF-β) in head kidney and gut (P < 0.05). Furthermore, dietary supplementation with P. monteilii JK-1 significantly enhanced the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) in liver and gut (P < 0.05). The results of high-throughput sequencing revealed that P. monteilii JK-1 showed no significant influence on the composition of gut bacteria, but prevented changes of microbial community caused by A. hydrophila infection. Additionally, a network-based approach was used to analyze the influence of P. monteilii JK-1 on the interspecies relationships among the gut microbiome. The results showed that P. monteilii JK-1 supplementation improved the complexity of the gut ecological network. Further analysis found that Cetobacterium was the keystone microbiota in maintaining interspecies interactions and the stability of the gut network. Finally, we used a partial least squares path model to prove that P. monteilii JK-1 did not directly improve growth performance and pathogen resistance but rather by regulating keystone taxa and gut network stability. These results suggest that P. monteilii JK-1 could be used as a feed supplement to improve the growth performance and pathogen resistance of grass carp.
Forecasting the effects of interest groups on Greek economy
Authors: Papadakis Haris , Atsalakis George S. 
Published: December 2022

AbstractFrom the modern bibliography there are many significant reports and indications for the action of special interest groups in Greece mainly after the fall of the court in 1974. Based on the theory of Olson as described in his book “The Rise and Decline of Nations” where developed analytically the implications of the special interest group’s action in a country, focus in the economic factor. With a thorough bibliographic survey, are recorded all the variables that have been used in the research for the impact of the interest groups. After the data for the case of Greece were collected and the normalization was done where it was necessary, the correlation between the variables was first checked. Then the Principal Component Analysis methodology was followed in order to arrive at the fewest variables for the study of the interest groups economic impact. Afterwards, the input and output variables separated, selected a suitable forecasting model of soft computing, the Adaptive Neural Fuzzy Inference System (ANFIS) for the study of the special interest groups impact in the Greek economy. ANFIS is a hybrid model which combines the advantages of Neural Network and the Fuzzy logic. Trying out all the different configurations of the model, as well as the different membership functions the corresponding results were recorded. For each result that emerged, the required evaluation was done, which has as its main criterion the low arithmetical errors of the model. The optimum results emerged from the ANFIS forecasting model, are presented in details along with the rules of the fuzzy logic and the corresponding diagrams, that confirm the success of the prediction.
Domain Adversarial Convolutional Neural Network Improves the Accuracy and Generalizability of Wearable-based Sleep Assessment Technology
Authors: Nunes Adonay S. , Patterson Matthew R. , Gerstel Dawid , Khan Sheraz , Guo Christine C. , Neishabouri Ali 
Published: December 2022

Abstract
Wearable accelerometers are widely used as an ecologically valid and scalable solution for long-term at-home sleep monitoring in both clinical research and care. The levels of accuracy with accelerometry-based sleep outcomes, however, have not improved much for the last 40 years. In this study, we applied deep-learning convolutional neural network (CNN) models to this task and demonstrated that this new model outperformed existing sleep algorithms in classifying sleep-wake and estimating sleep outcomes based on wrist-worn accelerometry. We further showed that, using a domain adversarial technique, this model generalized well to another dataset based on different wearable devices and activity counts, achieving an accuracy of 80.1 (sensitivity 84% and specificity 58%). Compared to the commonly used sleep algorithms, this model, termed DAsleepCNN, resulted in the smallest error in wake after sleep onset (WASO) and sleep efficiency (SE) outcomes. As wearable-based digital health technologies are increasingly used in clinical trials and care, improving the accuracy and generalizability of sleep algorithms for wrist-worn wearable data are of utmost importance. We here demonstrated that domain adversarial convolutional neural networks can improve the overall accuracy, especially the specificity, of sleep-wake classification using wrist-worn accelerometer data, substantiating its use as a scalable and valid approach for sleep outcome assessment in real-life.
Synthesis, biological evaluation, molecular docking and structure-activity relationship of caffeine derivatives
Authors: Khan Siraj , Buğday Nesrin , Yaşar Şeyma , Rehman Asim. ur. , Haq Ihsan Ul , Yaşar Sedat 
Published: December 2022

Abstract
A series of 8-(hetero)aryl caffeine was synthesized by C-H bond activation reaction using Pd-NHCs complexes as a catalyst. The derivatives were screened for their antioxidant, antimicrobials, and enzyme inhibitory activities. Furthermore, done their in-silico study. The 4a, 4b, 4e, 4f, 4g and 4n showed significant Total Antioxidant Capacity (TAC) of 64.03, 50.87, 70.02, 98.14, 71.81, 45.48 and 44.28 µg AAE/mg, respectively. The 4a, 4b, 4d, 4e, 6h, 4i, 4j, 4k and 4l were found active against Staphylococcus aureus at a minimum inhibitory concentration of 25, 12.5, 12.5, 12.5, 12.5, 6.25, 6.25, 12.5, 6.25 and 6.25 µg/ml, respectively. Some derivatives displayed activity against Escherichia coli, Bacillus subtilus, Klebsiella pneumonae and Pseudomonas auregenosa. A good activity was exhibited against Alternaria solani among five fungal strains. All the compounds (4a-4n) showed excellent protein kinase inhibitory activity except 4e, 4g and 4n. Additionally, derivatives showed α-Amylase enzyme inhibition potential (IC50 = 1.49 ± 0.317 to 7.44 ± 0.156 µg/ml) compared to standard Acarbose (IC50 = 4.34 ± 0.333 µg/ml). The 4b, 4d, 4j, 4m and 4n compounds displayed good α-Glucosidase inhibitory potential. Molecular modelling was done for protein kinase, α-Amylase, and α-Glucosidase enzymes. The results of these activities proved the caffeine derivatives to be bioactive.
Illuminating health aspects for immigrant Thai women in Swedish transnational marriages
Authors: Pongthippat Weerati , Östlund Gunnel , Darvishpour Mehrdad , Kijsomporn Jureerat , Gustafsson Lena-Karin 
Published: December 2022

Abstract

Background:
Women who are migrants experience discrimination and face major risks, including sexual exploitation, trafficking, and violence, which all affect their health and well-being.
This study explored critical health incidents resulting from marriage migration and the consequences experienced by immigrant Thai women in everyday life.
Methods: A qualitative explorative approach with in-depth interviews was used. Forty immigrant Thai women who currently or previously had a Swedish spouse were recruited for the study. An inductive critical incident technique was used to collect and analyze the data as the first step. In a second deductive step, the Newman system model was used when categorizing health dilemmas.
Results: The women reported 438 critical health incidents in five main areas: psychological health dilemmas included emotional abuse, feeling overwhelmed due to family responsibilities and the stress of leaving family behind. Sociocultural health dilemmas included transnational family duties or not performing family duties. Physiological health dilemmas included experiencing physical violence and environmental, domestic or work accidents. Developmental health dilemmas included failing health, difficulties in upholding the duties expected of a spouse in the target culture and caring for an elderly husband. Spiritual health dilemmas included critical incidents in which the women perceived themselves to have failed in their hopes and duties as a wife, which intensified their dependence on faith, particularly the Buddhist concept of karma.
Conclusion: The health and welfare practices that are included in marriage migration practices in Thailand and western countries, along with civil organizations such as Buddhist cultural associations in foreign countries that support immigrants, would benefit from the multicultural knowledge revealed by the present study. If accepted, this knowledge could facilitate healthcare and welfare support for women experiencing marriage migration.
Closed Endotracheal Suction Systems for COVID-19: Rapid Review
Authors: Ramírez-Torres Carmen Amaia , Rivera-Sanz Félix , Sufrate-Sorzano Teresa , Pedraz-Marcos Azucena , Santolalla-Arnedo Ivan 
Published: December 2022

Background
The increase in admissions to intensive care units (ICUs) in 2020 and the morbidity and mortality associated with SARS-CoV-2 infection pose a challenge to the analysis of evidence of health interventions carried out in ICUs. One of the most common interventions in patients infected with the virus and admitted to ICUs is endotracheal aspiration. Endotracheal suctioning has also been considered one of the most contaminating interventions.

Objective
This review aims to analyze the benefits and risks of endotracheal suctioning using closed suction systems (CSS) in COVID-19 patients.

Methods
A rapid review was carried out using the following databases: PubMed, MEDLINE, CINAHL, LILACS, the Cochrane Library, and IBECS. The data search included articles in English and Spanish, published between 2010 and 2020, concerning adult patients, and using the key words “endotracheal,” “suction,” and “closed system.”

Results
A total of 15 articles were included. The benefits and risks were divided into 3 categories: patient, care, and organization. Relating to the patient, we found differences in cardiorespiratory variables and changes in the ventilator, for example, improvement in patients with elevated positive and end-expiratory pressure due to maladaptation and alveolar collapse. Relating to care, we found a shorter suctioning time, by up to 1 minute. Relating to organization, we found fewer microorganisms on staff gloves. Other conflicting results between studies were related to ventilator-associated pneumonia, bacterial colonization, or mortality.

Conclusions
Aside from the need for quality research comparing open suction systems and CSS as used to treat COVID-19 patients, closed endotracheal suctioning has benefits in terms of shorter stay in the ICU and reduced environmental contamination, preventing ventilator disconnection from the patient, reducing the suctioning time—though it does produce the greatest number of mucosal occlusions—and preventing interpatient and patient-staff environmental contamination. New evidence in the context of the SARS-CoV-2 virus is required in order to compare results and establish new guidelines.
Late Neolithic Bone Shuttles from Barcın Höyük
Authors: ERDALKIRAN Mücella 
Published: December 2022

The subject of this paper is the tools which were discovered at a striking rate at Layer VI of Barcın Höyük, dated to the Late Neolithic Period (circa cal. 6000-6600 BC); which were made from the ribs of such animals as goats and sheep; and which are thin and flat and taper from their perforated wide tip towards their other tip.
Use-induced traces such as wear, shine, cracking, and breaking were determined on the perforations and at the tips of these tools, which are identified with 43 pieces at Barcın Höyük and which are analogous typologically and technologically. Hence, it was supposed that these tools might have been used in weaving or a sort of knitting process by reeving a thread through their perforations and they were identified as shuttles. Likewise, the presence of no other tool likely to have been used with this function supports this idea.
At Barcın Höyük, the shuttles were discovered from different contexts such as above the floor, in burials, at various pits, and on surfaces. Displaying significant integrity within themselves, these tools were determined as of the first phase of the settlement (VIe) and they reached their standard form and their rate of use increased in the next phase (Vd1).
In the Near East, shuttles are known particularly from the Levantine settlements as of Pre-Pottery Neolithic A. In Anatolia, however, the definition of weaving shuttle was either not used at all or used for different types of tools. I propose that such tools discovered at Barcın Höyük were shuttles, particularly due to the use traces.
PEMANFAATAN MEDIA PEMBELAJARAN E-LEARNING
Authors: Sulistyowati Endar , Aditya Riska Bayu 
Published: December 2022

The Indonesian government has begun to issue policies for implementing the new normal in various sectors, including the education sector. This of course makes the public must be able to condition the situation with the new rules made by the government. The rapid development of the world of education cannot be separated from the use of increasingly sophisticated technology. Global demands always demand the world of education to be in line with the development of information and communication technology for the world of education, especially in the learning process. For this reason, this study aims to (1) provide alternative learning media for lecturers and students using e-learning, (2) find out the benefits of educational technology with e-learning as a learning medium in the new normal era. Keyword : e-learning media, google classroom
PENGARUH FASILITAS SEKOLAH DAN MOTIVASI GURU TERHADAP EFEKTIVITA PROSES MENGAJAR DI MADRASAH ALIAYAH DDI BONTANG
Authors: Abdullah Martopan 
Published: December 2022

Martopan Abdullah. Drivers of School Facilities and Motivation of Teachers on the Effectiveness of the Teaching and Learning Process at Bontang DDI Madrasah. The teacher is one component that deals directly with the subject of students, must have the ability / compotency because it determines the quality of the learning process and the learning outcomes of students. Based on this, researchers are encouraged to analyze the teacher's potential by looking at the differences in the average teacher's composition in terms of motivation the teacher addresses the effectiveness of the teaching and learning process especially the teacher who teaches at Bontang DDI Madrasah Aliyah. This type of research is quantitative with 34 sample teachers in Bontang DDI Madrasah. from 34 populations. Data on teacher potency were collected using instruments in the form of tests developed on a Likert scale and questionnaire techniques. The data were analyzed using quantitative analysis, ie with multiple regression and ANOVA (SPSS 20) in one pathway at a 5 percent level of significance (5% ). The results of the study showed that there was an influence of facilities and teacher motivation on the effectiveness of the teaching and learning process in Bontang DDI Madrasah. In terms of training and experience in presenting material. Scientific facts found in this study indicate that the influence of school facilities and teacher motivation on the effectiveness of the learning process is enhanced by training. It is expected that teachers can develop their competence through several activities to further enhance work or teaching experience. Keywords: School Facilities, Teacher Motivation, Effectiveness of the Teaching Process
PENGARUH PENGGUNAAN MODEL PEMBELAJARAN TIPE COOPERATIVE INTEGRATED READING AND COMPOSITION (CIRC) TERHADAP HASIL BELAJAR EKONOMI PESERTA DIDIK KELAS X SEMESTER GENAP SMA NEGERI 1 METRO
Authors: Riski Kurniawati , Ningrum Ningrum 
Published: December 2022

The CIRC learning model is a collaborative based learning model through a reading and writing approach and oral and written language arts. In the learning process, the model forms a heterogeneous group that is responsible for the group's tasks so that more meaningful understanding and learning are formed. The problem in the research conducted by researchers is "There are still many students who have not experienced mastery learning in the economic learning outcomes of class X students of SMAN 1 Metro in the academic year 2018/2019". From these problems, the formulation of the problem in the study was "the influence of the Cooperative Integrated Reading and Composition (CIRC) learning model on the economic learning outcomes of class X students of SMAN 1 Metro 2018/2019 academic year". The influence of the use of Cooperative Integrated Reading and Composition (CIRC) learning models on the economic learning outcomes of class X students of SMA 1 Metro in school year 2018/2019. This study uses the experimental method (Quasi-Experimental), with the form of experimental design that is the form of The Non-Equivalent Control Group Design. In this design, the experimental class and control groups were not randomly selected but with purposive sampling techniques. Based on the results of the research conducted, the hypothesis is accepted, because the value of t count> t table can be seen in the attachment list G, at a significant level of 5%, namely 12.19> 1.70. Students who were declared complete with Minimum completeness criteria were 75 after being given treatment with a Cooperative Integrated Reading and Composition (CIRC) learning model 24 students or with a percentage of 77.42%, while the students in the unfinished category were seven students or with a percentage of 22, 58%. Thus it shows that there is a positive effect on the use of the Cooperative Integrated Reading and Composition learning model (CIRC) on the results of economic learning of class X students of SMAN 1 Metro 2018/2019 Academic Year. Keywords: Cooperative Integrated Reading and Composition Learning Model (CIRC), Economic Learning Outcomes
ANALISIS PENGARUH PELATIHAN KERJA TERHADAP PRESTASI KERJA KARYAWAN PADA UNIVERSITAS TRUNAJAYA BONTANG
Authors: Abdullah Martopan , Sabbatho Kalist 
Published: December 2022

Job training is needed so that the quality of the workforce increases. Trunajaya Bontang University in improving work performance is felt necessary to provide job training to staff and lecturers in the campus environment. This study aims to determine the relationship in Job Training to Employee Job Performance at Trunajaya University Bontang. The method of analysis in this study is the validity test, reliability test, Correlation Coefficient, Determination Coefficient, hypothesis testing. From the results of the interpretation of the calculation of the coefficient of determination, obtained value r2 = 0.79 (positive), this shows that 79% of the variation is explained by the positive relationship or influence between the variable "Job Training" with "Employee Job Performance", while the remaining 21% is influenced by other factors. Keywords: Job training, Job performance, staff
PENGARUH PENGUASAAN LITERASI DIGITAL SERTA MATA KULIAH KEWIRAUSAHAAN TERHADAP MINAT BERWIRAUSAHA MAHASISWA STKIP PGRI LUMAJANG
Authors: Putri Dwi Yanuarindah , Jayatri Fidyah 
Published: December 2022

Education today is not only about teaching and learning, the delivery of theories, and just questions and answers. From the elementary school level to college, educators and learners to students are expected to have an entrepreneurial character. This aims so that the mindset of students / students not only aspire to find jobs but are able to create their own jobs. Likewise with the development of the era that requires educators and students to master digital technology. It is very left behind if learning activities only use board stationery and manual teaching books. Technology is growing rapidly every year. STKIP PGRI Lumajang is one of the higher education schools that implements entrepreneurship courses that have the goal that graduates can create jobs for themselves and others by utilizing digital technology. So this research aims to find out the level of mastery of digital literacy and the impact of attending entrepreneurship lectures on student entrepreneurship activities. The method in this study is quantitative research correlational approach. Data collection uses observations, questionnaires, and other supporting documents. The results showed that there is an influence between the mastery of digital literacy to the interests of entrepreneurship students, mk entrepreneurship obtained by students there is influence, and there is a simultaneous influence between the two variations on the interest variables of entrepreneurship students. This is because knowledge about the basis of entrepreneurship makes students more confident in starting a business and mastery of technology also makes it easier for students to market their business results.Keywords: Digital Literacy; Entrepreneurship Courses; Student Entrepreneurship Interests
THE LOCAL WISDOM OF THE SUNDANESE-PEOPLE ON CULTURE, LANGUAGE, AND ARABS IN SUMEDANG DISTRICT
Authors: Fahrullah Tb. Ace , Kosasih Ade , Rohmayani Yani , Mahdi Sutiono 
Published: December 2022

The wisdom of the Sundanese-people of Sumedang towards Arabic culture, language, and arabs is still at the stage of conventional understanding. Understanding has not led to the reality that it should be. This is because the knowledge of the Sundanese-people of Sumedang is relatively and varied in obtaining the transformation of knowledge in the fields of social, political, cultural, linguistic and religious. The transformation of knowledge through education has not been evenly distributed. Education and teaching on geographical, social, and political sciences as well as culture have not been programmed. In the Sundanese-people of Sumedang there has not been a significant change in understanding the fields of Arabic culture, language, and nation. This study aims to describe the understanding of the Sundanese-people of Sumedang towards the Arabic culture, language, and nation, that grow and develop with the times. The method used is descriptive analysis. Data obtained from the literature and interviews. The results show that the understanding of the Sundanese-people of Sumedang towards the Arabic culture, language, and nation is still limited to information provided by non-formal education. Therefore, it is necessary to involve formal education from the Sumedang local government and the private sector.