bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Social and Psychological Impact of Acne Treatment: A Cross-Sectional Study of Blood Donors
Authors: Andersen Rune Kjærsgaard , Bouazzi Dorra , Erikstrup Christian , Nielsen Kaspar René , Burgdorf Kristoffer Sølvsten , Bruun Mie Topholm , Hjalgrim Henrik , Mikkelsen Susan , Ullum Henrik , Pedersen Ole Birger , Ernst Jemec Gregor Borut 
Published: August 2022

BackgroundAcne in adolescence and adulthood is believed to have a long-term impact on socioeconomic status (SES) and health-related quality-of-life (HRQoL) in adults.ObjectiveTo estimate the cross-sectional prevalence of medically treated (MedTreAc) and untreated acne (UnTreAc) and to characterize its long-term impact in adults.MethodsA nationwide cross-sectional study on 17 428 blood donors aged 18-35 was performed. Associations among acne and HRQoL, depressive symptoms, total income, and SES were investigated via linear/logistic/multinomial logistic regression analyses adjusted for relevant covariables. HRQoL was measured by the Short Form-12, and depressive symptoms by the Major Depression Inventory. The data were self-reported.ResultsOf the participants, 3591 (20.6%) and 1354 (7.8%) identified as the MedTreAc and UnTreAc phenotype, respectively. Neither phenotype was associated with a long-term impact on total income, but the MedTreAc group was associated with being an apprentice/student (OR = 1.26; 95% CI: 1.12, 1.42; P = 1.3×10-4) or high skill-level employee (OR = 1.22, 95% CI: 1.07; 1.39, P = .0023), while self-employment was more common for those with UnTreAc (OR = 1.53; 95% CI: 1.12, 2.06, P = .0061). Additionally, the UnTreAc group was associated with a lower mental HRQoL (SF-12 mental component summary score −1.05, 95% CI: −1.56, −0.54; P = 1.4×10-9) and increased odds ratio of depressive symptoms (OR = 1.44; 95% CI: 1.00, 2.02, P = .046).ConclusionIn this population of blood donors, the cumulative prevalence of MedTreAc and UnTreAc were 20.6% and 7.8%, respectively. Untreated acne had a long-term impact on psychosocial well-being in adulthood. It was associated with lower mental HRQoL and higher occurrence of depressive symptoms. Acne was not associated with a lower salary or SES.
Computed Dosimeter Dose Index on a 16-Slice Computed Tomography Scanner
Authors: Mekonin Tadelech S. , Deressu Tilahun T. 
Published: August 2022

A computed tomography dose index can be used to quantify the radiation dose received during a CT scan and it is an indicator of the radiation dose to the polymetaylenmetaAcrylate (PMMA) standardized phantom. The objective of this study was 2-fold. The first was to measure the computed tomography (CT) radiation dose for the head and body polymetaylelenmetaAcrylate (PMMA) phantoms and to determine the accuracy of the CT radiation dose parameter displayed on the CT scanner console; these were measured in this investigation and compared with the dose displayed on the CT scanner console. The dose was calculated using the formalism described in the American Association of Physics in Medicine (AAPM) Report 96. The second was to compare the dosimetric results of the head and body polymetaylelenmetaAcrylate (PMMA) phantoms with dose reference levels published in international journals, as well as to measure the central cumulative dose (DL′ (0)), as recommended by the American Association of Physics in Medicine (AAPM) report 111. This is a new, cutting-edge methodology for estimating the CT radiation dosage provided by the abdomen, thorax, and head of a PMMA phantom. We used a Philips Big Bore CT scanner with 16 slices. A CT dosimeter head phantom with a diameter of 16 cm, a CT dosimeter body phantom with a diameter of 32 cm, a 100 mm pencil chamber (PC), and a 20 mm short chamber (SC) were employed. These were coupled to an electrometer and a dosimetric readout device. The measured volume computed tomography dose index (CTDIvol) values were in good agreement with the CT radiation dose displayed on the corresponding CT scanner console. The percentage disagreement was less than 10%, with a maximal difference of 1.7% and 5.5% for the body and head phantom, respectively. The central cumulative dose (DL (0)) measurements (for L′ = 100 mm) also matched nominal or the corresponding computed tomography dose index (CT) scanner console volume computed tomography dose index (CTDIvol) values. In this case, the agreement is always below 3% for abdomen scans and 1.0% for head examinations. This result implies that the radiation dose supplied by the 16-slice computed tomography (CT) system was in good agreement with the international dose reference level and we observed something different.
A 4-year Retrospective Study on the Impact of the Dietary Program on Anthropometric and Metabolic Parameters among Overweight and Obese Subjects in Primary Health Care Centers in Qatar
Authors: Alam Muhammad T. , Veettil Shajitha T. , Abdulmajeed Jazeel , Sait Neelufur S. , Krishnan Jeyaram I. 
Published: August 2022

Aim. Obesity is a worldwide epidemic and one of the risk factors for many diseases including heart disease, diabetes mellitus, kidney disease, and cancer. The aim of this study was to review the impact of the local dietary program on anthropometric and metabolic parameters among overweight and obese subjects attending Primary Health Care Centers in Qatar from 2016 to 2019. Methods. A 4-year retrospective cohort study. Results. Among 10451 patients, the overall success rate of BMI reduction was 10% while 22.22% of population had ≥5% reduction in BMI from baseline. The median time for weight reduction was 3.2 years, with women showing earlier significant weight loss than men. The patients with 3–5 number of visits had earlier significant weight reduction than those with ≤3 visits and >5 number of visits. Greater weight reduction was seen in those with chronic diseases and who had constant follow up visits in the dietetic clinic during the study period. Conclusion. Our results are encouraging, showing improvement in the management of adult obesity with medical nutrition therapy through involvement and guidance in the community dietetic clinics. The dietetic clinic services could be an operative strategy to prevent expensive diabetic and cardiovascular events, mainly in high-risk patients.
Lung ultrasound description of a newborn with bronchial atresia: A case report
Authors: Rebollo-Simarro Marta , Alonso-Ojembarrena Almudena 
Published: August 2022

Introduction: Congenital pulmonary malformations are a heterogeneous group of embryological alterations at different stages of lung development, the most frequent being the congenital malformation of the airway. Lung ultrasound is a very useful tool in neonatal intensive care units, providing great value for differential diagnosis, as well as therapeutic response or early detection of complications. Case Report: The case is a newborn of 38weeks’ gestation who was followed by prenatal ultrasound control for suspected adenomatous cystic malformation type III in the left lung from week 22. She did not present complications during pregnancy. The study of Genetics and serological test were negative. She was born by urgent caesarean section due to breech presentation without requiring resuscitation, weighing 2.915 g. She was admitted to the Unit for study, remaining stable throughout her stay, with a normal physical examination. Atelectasis of the left upper lobe was appreciated by chest X-ray. Pulmonary ultrasound on the second day of life showed signs of consolidation in the left posterosuperior field with air bronchogram, without other alterations. In subsequent ultrasound controls, an interstitial infiltrate was observed in the left posterosuperior region, compatible with progressive aeration of the area, which was maintained until 1 month of life. The computed tomographic scan performed at 6months of age shows hyperlucency and increased volume in the left upper lobe with slight hypovascularization, accompanied by paramediastinal subsegmental atelectasis. There was a hypodense image at the hilar level. These findings were compatible with bronchial atresia, later confirmed by fiberoptic bronchoscopy. At 18months of age, surgical intervention was performed. Discussion and Conclusion: We present the first case of bronchial atresia diagnosed by LUS, thus adding new images to the very scarce literature currently available.
RESCUE BT 2, a multicenter, randomized, double-blind, double-dummy trial of intravenous tirofiban in acute ischemic stroke: Study rationale and design
Authors: Zi Wenjie , Song Jiaxing , Qiu Zhongming , Kong Weilin , Huang Jiacheng , Luo Weidong , Liu Shuai , Sang Hongfei , Yang Jie , Li Linyu , Tian Yan , Hu Jinrong , Saver Jeffrey L , Nogueira Raul G , Li Fengli , Yang Qingwu 
Published: August 2022

Background: Tirofiban is a glycoprotein IIb/IIIa receptor inhibitor that has been shown to be effective in the treatment of acute coronary syndromes. However, it remains unknown whether it improves outcomes in patients with acute ischemic stroke. Objective: This trial investigates the efficacy and safety of tirofiban compared with aspirin for acute ischemic stroke within 24 h after symptom onset. Methods and design: The Efficacy and Safety of Tirofiban Compared with Aspirin in the Treatment of Acute Ischemic Stroke (RESCUE BT 2) Trial is an investigator-initiated, prospective, randomized, double-blind, double-dummy, multicenter clinical trial. Up to 1158 eligible patients will be consecutively randomized to receive antiplatelet therapy with tirofiban or aspirin in 1:1 ratio across approximately 100 stroke centers in China. Outcomes: The primary endpoint is the proportion of patients with excellent functional outcomes defined as a modified Rankin scale score of 0 to 1 at 90 days after randomization. Lead safety endpoints include mortality at 90 days and symptomatic intracerebral hemorrhage within 48 h after treatment. Trial registry number: ChiCTR2000029502 ( www.chictr.org.cn ).
Comparison of laboratory characteristics of gastrointestinal symptoms and nongastrointestinal symptoms in patients infected with COVID-19: a systematic review and meta-analysis
Authors: Zhao Rui , Shi Jie , Song Yichuan , Zhang Rui 
Published: August 2022

Background: The Coronavirus Disease 2019 (COVID-19) pandemic poses a massive crisis to global public health. Gastrointestinal (GI) symptoms are increasingly reported in COVID-19. The characteristics of laboratory findings of COVID-19 are critical for clinical diagnosis and treatment. Objectives: The study aimed to summarize laboratory features in COVID-19 with GI symptoms and non-GI symptoms. Design: This study was a systematic review and meta-analysis. Electronic literature searches were conducted for studies that included patients infected COVID-19 with GI symptoms and non-GI symptoms. GI symptoms included diarrhea, abdominal pain, nausea and vomiting, and anorexia. This study used a random-effects model to assess pooled data. Data sources and methods: We systematically searched PubMed, Embase, Cochrane, Web of Science for studies through 31 October 2021, with no language restrictions. We used the following search terms: ‘COVID-19’ OR ‘2019-nCoV’ OR ‘SARS-CoV-2’ OR ‘coronavirus 2019’ OR ‘severe acute respiratory syndrome coronavirus 2’ OR ‘coronavirus’ OR ‘novel coronavirus’ OR ‘nCoV’ AND ‘gastrointestinal symptoms’ OR ‘digestive symptoms’ AND ‘clinical feature’ OR ‘clinical characteristics.’ Data mostly originated from Chinese and American studies. Results: Of 796 identified studies, 14 were eligible and were included in our analysis ( N = 8396 participants). Meta-analysis showed that GI symptoms group had an elevated alanine aminotransferase (ALT) [pooled mean difference (MD), 4.5 U/L; 95% confidence interval, [0.45, 8.55]; p = 0.03; I2 = 87%]. No publication bias was detected by Begg’s and Egger’s regression test ( p = 0.130). COVID-19 with the GI symptoms also showed a trend toward decreased white blood cell count, lymphopenia, neutrophilia, thrombocytopenia and elevated total bilirubin. Conclusion: GI symptoms are common in COVID-19. No significant differences were found in most laboratory indicators except elevated ALT. Registration: CRD42020209039 (PROSPERO).
Intraoperative Technical Tips to Improve Fusion Between the First and Second Metatarsals in the Original Lapidus Procedure
Authors: Nishikawa Danilo Ryuko Cândido , Duarte Fernando Aires , Saito Guilherme Honda , Pontin Pedro Augusto , Mendes Alberto Abussamra Moreira , Prado Marcelo Pires 
Published: August 2022

The modified Lapidus procedure (MLP), which consists of fusion between the first metatarsal (M1) and medial cuneiform, has been widely performed with satisfactory clinical outcomes, but it has a variable nonunion rate ranging between 4% and 10% and loss of correction in up to 5.8% of the cases. Excessive motion around the site of tarsometatarsal arthrodesis, specially at the intercuneiform joint, is probably the reason. The original Lapidus procedure (OLP), which includes fusion of the M1 to second metatarsal (M2), may be beneficial in preventing nonunion and recurrence. The objective of this study was to describe intraoperative technical tips in the OLP to improve M1 to M2 fusion, which may prevent complications. Since the Lapidus procedure continues to gain popularity, it is the authors opinion that the OLP requires special attention because it is a more technically demanding surgery compared to the MLP. Level of Evidence: Level V: Expert opinion
Remote patient monitoring for chronic heart failure in France: When an innovative funding program (ETAPES) meets an innovative solution (Satelia® Cardio)
Authors: Pages N , Picard F , Barritault F , Amara W , Lafitte S , Maribas P , Abassade P , Labarre J Ph , Boulestreau R , Chaouky H , Abdennadher M , Lemieux H , Lasserre R , Bedel C , Betito L , Nisse-Durgeat S , Diebold B 
Published: August 2022

Introduction Remote patient monitoring (RPM) is a telehealth activity to collect and analyze patient health or medical data. Its use has expanded in the past decade and has improved medical outcomes and care management of non-communicable chronic diseases. However, implementation of RPM into routine clinical activities has been limited. The objective of this study was to describe the French funding program for RPM (known as ETAPES) and one of the RPM solution providers (Satelia®) dedicated to chronic heart failure (CHF). Methods A descriptive assessment of both the ETAPES funding program and Satelia® RPM solution was conducted. Data were collected from official legal documents and information that was publicly available online from the French Ministry of Health. Results and Discussion ETAPES was formally created in 2016 based on previous legislation pertaining to the national health insurance funding strategy. However, it only started to operate in 2018. Patients with CHF were only eligible if they were at medium or high risk of re-hospitalization with a New York Heart Association (NYHA) score superior or equal to two and a BNP>100 pg/ml or NT pro BNP>1000 pg/ml. Medical monitoring was supported through the therapeutic education of a patient on the RPM model of care with a minimum of three training sessions during the first six months. The use of Satelia® Cardio is noteworthy since it relies only on symptomatic monitoring through which the patient manually reports their information by answering a simple questionnaire on a regular basis and does not rely on any connected devices. Conclusion Innovative funding programs and solutions for RPM need real-world evaluation in the future.
Opportunities and Challenges for Private Education in China: A Review of the Latest Policy Revisions
Authors: Liu (刘莉莉) Lili 
Published: August 2022

Purpose This study reviews the latest revisions to “Implementation Regulations of the Private Education Promotion Law of the People's Republic of China.” In doing so, this study provides a comprehensive overview of the policy and its history, as well as the future outlook of private education in China. Design/Approach/Methods Data were collected from the official website of the Ministry of Education of China as well as the media. Findings This study identifies the background, rationale, major breakthroughs, and impacts of the revised policy. Originality/Value This study provides a comprehensive analysis of the latest revisions to “Implementation Regulations of the Private Education Promotion Law of the People's Republic of China.” In addition to an academic interpretation of these policy changes, it suggests how private education in China may develop.
Posterior Approach With Osteotomized Debridement Versus Combined Anterior and Posterior Approach in Treating Thoracolumbar Tuberculosis: A Retrospective Cohort Study
Authors: Ma Shengbiao , Zhou Zhenhai , Yu Honggui , Zhong Junlong , Xiong Jiachao , Xu Jiang , Deng Wenqiang , Cao Kai 
Published: August 2022

Study Design Retrospective cohort. Objectives To compare outcomes of posterior osteotomized debridement (OD) with combined anterior and posterior approach (AP) in treating thoracolumbar tuberculosis (TB). Methods This study reviewed 178 patients who were diagnosed as active thoracolumbar TB and surgically treated in our center. One hundred and two patients underwent posterior OD, interbody fusion with titanium mesh cage (TMC), and instrumentation (group A). Seventy-six patients underwent one-stage posterior instrumentation, anterior debridement, and interbody fusion with TMC (group B). Patients’ clinical outcomes were compared between the 2 groups. Results Erythrocyte sedimentation rate and C-reactive protein in all patients returned to normal levels within 3 months after surgery, and no recurrence occurred during the follow-up. Compared with AP approach, OD surgery was less invasive and with a lower cost (¥ 70 581 ± 17 645 vs ¥ 87 600 ± 27 328; P < .05). Patients treated by OD showed more significant improvements in Visual Analog Scale (VAS) and Oswestry Disability Index (ODI) than those treated by AP approach 3 months postoperatively (VAS: 3.0 ± .7 vs 3.7 ± .9; ODI: 14.7 ± 4.4 vs 20.6 ± 4.6). Two groups showed similar postoperative kyphosis correction and final follow-up correction loss ( P = .361 and P = .162, respectively). The OD method had a lower complication rate than AP approach (9.8% [10/102] vs 35.5% [27/76]; P < .05). Conclusions Posterior OD is effective in treating active thoracolumbar TB. Compared with traditional AP approach, OD surgery has less surgical invasiveness, lower complication rate, and shorter fusion time.
Factors influencing stress during the second imposed of COVID-19 social restrictions in Indonesia
Authors: Sulistyawati Sulistyawati , Aji Budi , Rokhmayanti Rokhmayanti , Wijayanti Siwi Pramatama Mars 
Published: August 2022

Background: The spread of the COVID-19 virus has had a significant impact on the governmental and social aspects, as well as to the psychological status of the population. In Indonesia, social restriction was a strategy to limit people’s mobility to reduce virus transmission. As social beings, the imposition of social restriction makes them fall into stress due to feeling lonely, and some cannot earn money. The aim of the study was to assess the factor association of stress level and resilience of the Indonesian people during the imposition of the second social restriction due to the COVID-19 pandemic. Design and method: A cross-sectional study was performed on respondents aged at least 18 years on 29 July–16 August 2021, when the social restriction was enforced for the second time. The online survey was conducted through several social media platforms (Facebook, Instagram, Twitter, and WhatsApp) to 256 respondents. The analysis was carried out descriptively and analytically using the chi-square and binary logistic regression. Results: This study shows that there is a significant relationship between age ( p < 0.001), marital status ( p < 0.001), occupation ( p < 0.001), income before and during the pandemic ( p < 0.001) and resilience level to stress level among Indonesian. Resilience level is the only protective factor for people to not get stressed. Being normal resilience put them at 0.05 times (95% CI 0.01–0.76) more likely to have low perceived stress than low resilience. Conclusion: Resilience level is the only factor that influence stress level among people in Indonesia during the second imposed social restriction in Indonesia.
Management of Intracranial Sinusitis Complications in Children and Adolescents: Similarities and Differences Among Otolaryngology Subspecialists
Authors: Adil Eelam , Kim Jamie J. , Kawai Kosuke , Cunningham Michael J. 
Published: August 2022

The purpose of this study was to compare the management of intracranial sinusitis complications in pediatric patients between members of the American Rhinologic Society (ARS) and the American Society of Pediatric Otolaryngology (ASPO). A cross‐sectional web‐based survey was distributed twice to the ASPO and ARS membership over an 8‐month period. The overall survey response rate was 12.1% (7.5% of ARS members and 17.3% of ASPO members). Recommended management was similar with respect to the use of intravenous antibiotics, nasal saline irrigations, topical decongestants, and nasal steroid sprays. Recommendations diverged with regards to systemic steroid use and urgent/emergent endoscopic sinus surgery (ESS). ARS members were more likely to recommend systemic corticosteroids. ASPO members were more likely to recommend immediate ESS. Based on survey responses, we found differences in practice patterns among subspecialists, which indicates additional collaborative research between societies is necessary to develop and disseminate evidence‐based guidelines for these patients.Level of Evidence: 4
Improving health literacy with mumps, measles and rubella (MMR) vaccination: comparison of the readability of MMR patient-facing literature and MMR scientific abstracts
Authors: Downey Tina , Millar Beverley C. , Moore John E. 
Published: August 2022

Background: Historically, there have been many factors that have influenced mumps, measles and rubella (MMR) vaccine uptake, including media bias, social/economic determinants, parental education level, deprivation and concerns over vaccine safety. Readability metrics through online tools are now emerging as a means for healthcare professionals to determine the readability of patient-facing vaccine information. The aim of this study was to examine the readability of patient-facing materials describing MMR vaccination, through employment of nine readability and text parameter metrics, and to compare these with MMR vaccination literature for healthcare professionals and scientific abstracts relating to MMR vaccination. Materials and methods: The subscription-based online Readable program (readable.com) was used to determine nine readability indices using various readability formulae: Established readability metrics ( n = 5) (Flesch–Kinkaid Grade Level, Gunning Fog Index, SMOG Index, Flesch Reading Ease and New Dale-Chall Score), as well as Text parameters ( n = 4) (sentence count, word count, number of words per sentence, number of syllables per word) with 47 MMR vaccination texts [patient-facing literature ( n = 22); healthcare professional–focused literature ( n = 8); scientific abstracts ( n = 17)]. Results: Patient-facing vaccination literature had a Flesch Reading Ease score of 58.4 and a Flesch–Kincaid Grade Level of 8.1, in comparison with poorer readability scores for healthcare professional literature of 30.7 and 12.6, respectively. MMR scientific abstracts had the poorest readability (24.0 and 14.8, respectively). Sentence structure was also considered, where better readability metrics were correlated with significantly lower number of words per sentence and less syllables per word. Conclusion: Use of these readability tools enables the author to ensure their research is more readable to the lay audience. Patient co-production initiatives would help to ensure that not only can the target audience read the literature, but that they understand the content. Increased patient-centric focus groups would give better insights into reasons for MMR-associated vaccine hesitation and vaccine refusal.