bluuebunny/crossref_metadata_2025_split huggingface dataset:
Egy sikertelen kísérlet
Authors: Sato Dan 
Published: May 2022

This paper sketches out the early phase of the academic discipline ‘Western (or European) Legal History’ in Japan through the case of Satoshi Nishimoto, who was one of the first scholars to specialise in this discipline. Nishimoto studied in Germany during the National Socialists era. Following his return to Japan, he published a series of papers which were influenced by national socialistic ideology. Due to the fact that the subjects of these papers seemed to bare no relation to European legal history, he was unable to gain much recognition as a legal historian. However, it seems that these papers were an attempt to introduce the research methodology prevalent in Germany at the time of his studies, namely that of legal history as either serving politics or needing to be combined with geopolitics. In any case, his attempt ended in failure.
A prospective study comparing incision and curettage with intralesional injection of triamcinolone acetonide for treating chalazia in South Indian population
Authors: Govindaraj Bhavna , Natarajan Manjunath 
Published: May 2022

To compare the results and recurrences of incision and curettage with intralesional triamcinolone acetonide (TA) in treating chalazia. Patients with chalazia were treated with either intralesional injection of triamcinolone acetonide or incision and curettage (I & C) by randomisation into 2 different groups. The patients were then followed up after 2 weeks and then 3 months post-procedure to assess the size. A size reduction of 90% was considered as adequately treated for the purposes of this study. Out of a total of 60 patients selected for the study, 30 patients underwent intralesional triamcinolone injections & the other 30 patients incision & curettage for their chalazia respectively. Adequate treatment thresholds were achieved in 24% patients (80%) in the Triamcinolone Acetonide group and 29 patients (96.67%) in the incision & curettage group. Recurrence of the lesion was seen in 9 patients (30%) in the triamcinolone acetonide group & 2 patients (6.67%) in the incision & curettage group. Intraocular pressure & visual acuity remained unaltered during follow-ups in both groups. We found both methods to have good success rates. The I & C group had lesser recurrences and higher success rates when compared to the TA group
The clinical profile and causative factors for eyelid lacerations at a tertiary eye care centre in South India
Authors: Govindaraj Bhavna , Natarajan Manjunath 
Published: May 2022

The aim of this study was to identify the clinical profile and the likely causative factors for eyelid lacerations at a tertiary eye care centre in South India. This was done so that the data can be used to identify the most common patterns of injuries, using which effective safety measures can be developed. A retrospective study was done through a review of hospital records of 57 cases of traumatic eyelid lacerations who presented to our centre in the period between Jan 2017 to Jan 2018. The data collected were related to epidemiological factors, causative factors, site of injury, structures involved and association with visual outcome. Of the 57 patients included in our study, 39 were men & 18 were women. The mean age of patients was 17+_ 2.8 years. As far as the location of injury was concerned, 67.32% patients sustained them while outdoors, 10.52% at home, 23.16% at their workplace. The most common mode of injury was by trauma caused accidentally in 36 patients (63.15%), assault in 11 patients (19.29%), falls in 10 patients (17.54%), laceration involving either the punctum or canalicular drainage system were seen in 33.26% patients. Based on the Snellen chart visual acuity of the injured eye/s was as follows: in 54 patients (90.6%), the visual acuity was better than 6/60; while in 3 patients (9.4%), the visual acuity was worse than 6/60.
Comparative evaluation of Goldman applanation tonometer, Perkins tonometer, and Non-contact tonometers in a tertiary care hospital
Authors: Kumar Sinha Durgesh , Sujatha M A Rani , Karanvi Shweta B , Saifullah Bokhari Syed , KC Ranjitha , BJ Sannidhi 
Published: May 2022

Measurement of intraocular pressure (IOP) is basic investigation in a general ophthalmic workup. We attempt to determine the agreement in the measurement of IOP obtained by Goldman applanation tonometer, Perkin’s applanation tonometer, Non-contact tonometer in patients attending general ophthalmology OPD in a tertiary care centre in South India and its use in a community ophthalmology settingA cross-sectional analytical study in which IOP was measured in patients using the three tonometers. Central corneal thickness (CCT) was measured using Ultrasonic pachymetry. Bland Altman analysis was done to evaluate the agreement between instruments. 800 eyes of 400 patients were included in the study. By Bland Altman method, Perkin’s tonometer was found to have better correlation to IOP obtained by Goldman applanation tonometer. Perkin’s tonometer was found to be most accurate when CCT was in the range of 501–550 microns and noncontact tonometer was found to be least accurate when CCT was greater than 600 microns. On comparing correlation at different age groups, both the methods had better correlation at &#60;40 years age group.Both the tonometers showed a significant correlation with the gold standard technique GAT over a range of IOP and CCT with the Perkin’s tonometer better than the NCT. This study proves that Perkin’s tonometer can be recommended as a reliable screening tool in community outreach ophthalmology services. The twin advantages of portability and availability make the Perkin’s tonometer a popular choice among ophthalmology trainees and optometrists in a developing country like India.
El genoma humano: llenando los vacíos
Authors: Gómez Gutiérrez Alberto 
Published: May 2022

El Consorcio Telómero a Telómero (T2T) ha completado la secuencia de un desafiante 8% del genoma humano que quedó que quedó sin resolver en el Proyecto Genoma Humano.En esta visualización, cada cromosoma comienza en la parte inferior derecha y se envuelve alrededor de un centro tácito, con los cromosomas X y 1 a 22 dispuestos desde de afuera hacia adentro (el cromosoma Y no se se muestra). Las regiones recién completadas se resaltan en rojo.
Gráfico: V. Altounian/CienciaDatos: Consorcio T2T
Sergey Nurk, Sergey Koren, Arang Rhie, Mikko Rautiainen, et al. (2022). The complete sequence of a human genome. Science 2022, Vol. 376, No. 6588, pp. 44-53. https://doi.org/10.1126/science.abj6987
Between the Normative and the Interpretive Approach: Student Performance Online Evaluation Challenges in Journalism and Communication Higher Education
Authors: Vasile Aurelia Ana , Bălășescu Mădălina 
Published: May 2022

n times of pandemic, higher education programmes had to switch quite unexpectedly from educational strategies and techniques that applied within a classical kind of college environment, to the online platforms.
If all sorts of platforms proved feasible for seminars, in the case of courses and evaluation activities, some difficulties were encountered and, consequently, demanded special concern and conjugated efforts to roll things out through the thick and thin of a period that required a high level of adaptability on the part of higher education leadership and management, as well as on the part of professors and students.
A survey addressed to the students and to the professors at the University of Bucharest, College of Journalism and Communication Studies revealed intriguing information regarding our main topic, that of the online student performance evaluation challenges in the journalism and communication higher education in Romania. The response of the majority of the professors to such an unexpected turnout in education within the context of the pandemics was that of a spectacularly more flexible approach mostly to the assessment of student performance, our topic at stake for this research endeavour.
Within our research focus, the student and professor preference for measurement and for a normative approach to online evaluation, on the one hand, versus the option for appreciation within an interpretive approach, on the other hand, may account for interesting developments in the educational system of the near future that we seem to have stepped in quite abruptly due to the pandemic.
Artistic and Figurative Thinking in the Structure of Educational Activity of Future Masters in Music Art
Authors: Vodianyi Bohdan , Vodiana Valentyna , Bobyk Liliia , Yevhenieva Mariia , Oronovska Larysa , Dovgan Oksana 
Published: May 2022

The purpose of the article is to reveal the neuropedagogical aspects of artistic and figurative thinking of future masters of music in the structure of their educational activities. The neuropedagogical approach as a scientific direction is still in its infancy and needs significant support in the educational environment. The degree of demand for continuous education of music specialists to make the right methodological decisions in their professional activities is emphasized. Artistic thinking in the system of training masters in music is a priority and is one of the most important tasks of their educational process at this scientific level. But the search for innovative methods of artistic and figurative perception of musicians is often complicated by an empirical approach to solving this problem.
The specifics of neuropedagogical training for the development of artistic and figurative thinking of higher education students, which is associated with the creative interaction of teacher and student is analyzed. The regularities of training future musicians which are due to the need to solve problems for the development of creative musical and professional thinking are revealed. The importance of interdisciplinary integration of humanitarian, music-theoretical and special knowledge is emphasized, which is the basis for the formation of a high level of professionalism of future masters in music. The interaction of intellectual, auditory and emotional components in the process of development of artistic and figurative thinking of the future musician is substantiated.
The Exacerbation of Lutembatcher Syndrome in The Setting of COVID-19 infection: A Rare Case Report
Authors: Nugraha Adriyawan Widya , Azmi Yusuf , Lusida Terrence T. E. , Namretta Lisca , Suyani Nida A. , Laitupa Fitriyani S. 
Published: May 2022

Lutembatcher syndrome is a rare cardiac condition characterized by a combination of the atrial septal defect (ASD; congenital or iatrogenic) and mitral stenosis (MS; congenital or acquired). Patients with Lutembatcher syndrome and adults with congenital heart disease (ACHD) in general may be at high risk when accompanied by coronavirus disease 2019 (COVID-19). Since there is no published study on the impact of COVID-19 on ACHD, little is known about management strategies in this subset of patients. Herein, we report a young adult female presented with abdominal discomfort, swollen legs, fever, cough, and dyspnea. The patient had developed palpitation and exercise intolerance five years ago but paid it no attention. Echocardiography revealed large secundum type ASD with severe MS (Wilkins score of eight) and a nasopharyngeal swab confirmed SARS-COV-2 infection. The patient was diagnosed with Lutembacher syndrome and COVID-19. Intensive treatment was given to relieve symptoms due to heart failure and to treat COVID-19 pneumonia. Patients with Lutembatcher syndrome are at a higher risk of being infected with COVID-19 and manifest into severe infections. Therefore, determining the risk of infection and the severity of COVID-19 in ACHD patients are required during the pandemic.
Weighted gene co-expression network analysis of modules and biomarkers in early-phase acute lung injury with time-series gene expression profile
Authors: Li Jing , Yang Yanming , Fan Lili , Cui Zhengjun 
Published: May 2022

Abstract
Background: The pathogenesis of acute lung injury (ALI) is affected by a complex network of molecular factors and/or pathways; however, the time-series molecular mechanisms profile underlying ALI are unclear. Therefore, Time-series gene expression dataset GSE2565 was obtained from Gene Expression Omnibus, and weighted gene co-expression network analysis (WGCNA) was performed to identify time-series hub modules and genes and explore their associations with the progression of ALI. Methods: Time-series gene expression dataset GSE2565 was obtained from Gene Expression Omnibus, the data were normalized, differentially expressed genes were screened, and WGCNA was performed to identify hub modules. In addition, Gene Ontology and Kyoto Encyclopedia of Genes and Genomes pathway enrichment analyses were conducted, and integration of module analysis and CytoHubba analysis were used to identify hub genes. Finally, receiver operating characteristic (ROC) curve analysis was used to measure the predictive accuracy of the hub genes. Results: Module–trait analysis revealed that the red module, which was negatively correlated with the 8-h analysis time-point, was mainly involved in the regulation of the circadian rhythm, whereas the pink module, which was positively correlated with the 8-h analysis time-point, was mainly involved in regulation of cell death. Five hub genes, Bnip3, Cdh11, Fam134b, Sult1a1, and Zbtb16, were identified following ROC curve analysis. Conclusions: our analysis of time-series expression data identified co-expression modules and pathways that were correlated with early-phase ALI. Moreover, the hub genes identified could provide new insights into the molecular mechanisms of ALI.
A retrospective review of vaccine wastage and associated risk factors in the Littoral Region of Cameroon during 2016-2017
Authors: Nkenyi Rene , Pak Gi Deok , Chon Yun , Tonga Calvin , Park Se Eun , Kang Sunjoo 
Published: May 2022

Abstract
Background
Immunization is an effective preventive health intervention. In Cameroon, the Expanded Program on Immunization (EPI) aims to vaccinate children under five years of age for free, but vaccination coverage has consistently remained below the national target. Vaccines are distributed based on the target population size, factoring in wastage norms. However, vaccine wastage rates (VWR) may differ among various settings. Our study aimed to assess vaccine wastage for different site settings, seasonality, and vaccine types in comparison to vaccination coverage in order to provide comprehensive insights on vaccine wastage.
Methods
A retrospective data collection and analysis was conducted on the immunization and vaccine wastage data in the Littoral Region of Cameroon during the period of 2016 and 2017. Health districts were classified as urban or rural, seasonality was categorized as rainy or dry season, and vaccine types were grouped into liquid, lyophilized, oral, and injectable vaccines. The VWR and vaccination coverage rates (VCR) were calculated, and the vaccine waste factor was investigated.
Results
The VWR of Bacillus Calmette-Guérin (32.19%) was the highest, followed by measles and rubella (19.05%) and yellow fever (18.34%) among all EPI vaccines in the Littoral Region of Cameroon during 2016 and 2017. Single-dose vaccine vials exhibited lower VWR than multi-dose vials. Dry season was associated with higher VWR for most vaccines though more lyophilized vaccines (BCG, MR, YF vaccines) were wasted in rainy season in 2016. VWR was persistently higher in rural than urban health districts. The months of February and November saw a decrease in VCR. The study found an overall negative correlation between VCR and VWR.
Conclusions
Multiple factors may cause wastage of EPI vaccines in Cameroon. Vaccination area characteristics, seasonality, types of vaccines such as multi- or single-dose, lyophilized or injectable vaccines are related to VWR in Littoral Region. Further research on vaccine wastage and vaccination coverage across Cameroon is needed to better understand the socio-behavioural aspect of vaccine in-take that may affect the level of vaccination and vaccine wastage. Public health system strengthening is warranted to adapt more real-time monitoring of VWR and VCR for each vaccine in the government’s immunization programs.
Spatiotemporal characteristics of current and projected rainfalls over East Africa: Insights from precipitation concentration and standardized precipitation indices
Authors: Assamnew Abera Debebe , Tsidu Gizaw Mengistu 
Published: May 2022

Abstract
This study has used monthly rainfalls from Regional Climate Models (RCMs) experiments conducted in the frame work of the COrdinated Regional Downscaled EXperiment (CORDEX) project for historical and future periods. The deriving General Climate Models (GCMs) are obtained from Coupled Model Inter-comparison project phase 5 (CMIP5). Rainfalls from RCMs for the historical period, the two scenarios (i.e. Representative Concentration Pathway (RCP) scenarios representing radiative forcing of 4.5 m/W2 (RCP4.5) and 8.5 m/W2 (RCP8.5)) and Climate Research Unit (CRU) are used to determine precipitation concentration index (PCI), standardized precipitation index (SPI), and trend. The PCI, SPI, and trend derived from CRU and Historical Ensemble Mean (HEM) rainfalls are used to (1) assess the fidelity of the models in capturing observed spatiotemporal characteristics of rainfall over East Africa (EA) and (2) assess the relative change in the pattern of rainfall extremes and trends from the two scenario projections. From CRU and HEM-based SPI, the normal rainfall years are about 62–80% and 62–71% of the time of the historical period (1951–2005) during March-May (MAM) and September-December (SOND) respectively. The spatial dipole pattern captured by CRU and HEM is visible in the projections under the two scenarios implying that both radiative forcing are not expected to alter current rainfall regime over EA. In addition, normal rainfall is expected to occur for 62–68% and 65–72% of the time of the projection period (2006–2100) during MAM and SOND respectively. The projected rainfall shows wetting trend during MAM in contrast to the historical observations of dry trends over much of EA.
Comparative Analysis of Bioaccumulation of Cadmium, Lead, Chromium, Copper and Nickel in Wheat Crop
Authors: Mazhar Muhammad Waqar , Saif Saira , Irfan Muhammad , Raza Ahmad , Iram Wajeeha , Tahir Hira , Mazhar Fatima 
Published: May 2022

Abstract
In this research, the comparative analysis of heavy metals has been studied. An experiment was conducted to determine heavy metals bioaccumulation in wheat as wheat is the staple cereal crop consumed as food globally. Abiotic stress disturbs the metabolic pathway of plants, and the bioaccumulation of the metals cause enzymatic degradation, reduction in photosynthesis, increased level of the ROS species. Comparative analysis of the Cd, Pb, Cr, Cu, and Ni was analyzed with the help of Inductively Coupled plasma optical emission spectrometry (ICP-OES). The results show that Ni has a maximum value of BCF in shoots and roots, whereas the Cr has maximum TF values. SOD and POD assays were performed to check the ROS level in the plants. The results show that plants increase their anti-oxidant enzymes for the scavenging of ROS produced against the bioaccumulation of heavy metals.
In Vivo Effect of Ampicillin, Enrofloxacin, Colistin, and Sulfonamides on Sperm Parameters in Breeding Roosters
Authors: Linda MOHAMMEDI , MESSAÏ Ahmed , Hamida OUAMANE , Sofiane BENCHARIF , Leghel TOUAZI , Mokrane IGUER-OUADA 
Published: May 2022

Abstract
The present study was aimed to investigate the effect of commonly prescribed antibiotics on sperm parameters in breeding roosters. Twenty adult breeding roosters were divided into four experimental groups receiving different antibiotics during 9 consecutive days (G1: 30 mg/kg of Ampicillin, G2: 10 mg/kg of Enrofloxacin, G3: 75000 UI/kg of Colistin, and G4: 1g/liter of a Sulfonamides association. The measurements were performed on T0 (before treatment), T3, and T9 representing 3 and 9 days of treatment. The analysed parameters were: total motility (TM%), progressive motility (PM%), curvilinear velocity (VCLμm/s), straight-line velocity (VSLμm/s), average path velocity (VAPμm/s), amplitude of the lateral head displacement (ALH μm), linearity (LIN %) and the beat-cross frequency (BCF Hz). Antibiotics did not affect ejaculates color, pH (8 ± 0.5), seminal fluid viscosity, and agglutination. Ampicillin increased slightly sperm volume on T3 with no significant change on T9. No significant effect was observed on T3 on sperm count, viability, and TM. PM deceased slightly on T3. Enrofloxacin and Colistin induced a significant decrease in sperm volume, count, viability, TM, and PM on T3. On T9 some parameters were improved to be closer to those observed at T0. Ampicillin, Colistin, and Enrofloxacin decreased significantly all (CASA) Computer Aided Sperm Analysis kinematics parameters. The highest impact was observed on the third day of treatment (T3). Sulfonamides decreased sperm volume and gametes concentration, but enhanced significantly sperm viability, total motility (TM), progressive motility (PM), and all kinematic parameters.
Widely Tunable Berry curvature in the Magnetic Semimetal Cr1+dTe2
Authors: Fujisawa Yuita , Pardo-Almanza Markel , Hsu Chia-Hsiu , Atwa Mohamed , Yamagami Kohei , Krishnadas A. , Chuang Feng-Chuan , Khoo Khoong Hong , Zang Jiadong , Soumyanarayanan Anjan , Okada Yoshinori 
Published: May 2022

Abstract
Magnetic semimetals have increasingly emerged as lucrative platforms hosting spin-based topological phenomena in real- and momentum spaces. Of particular interest is the emergence of Berry curvature, whose geometric origin, accessibility from Hall transport experiments, and material tunability, bodes well for new physics and practical devices. Cr1+δTe2, a self-intercalated magnetic transition metal dichalcogenide (TMD), exhibits attractive natural attributes relevant to such applications, including topological magnetism, tunable electron filling, magnetic frustration etc. While recent studies have explored real-space Berry curvature effects in this material, similar considerations of momentum-space Berry curvature are lacking. Here, we systematically investigate the electronic structure and transport properties of epitaxial Cr1+δTe2 thin films over a wide range of doping, δ (0.33 – 0.71). Spectroscopic experiments reveal the presence of a characteristic semi-metallic band region near the Brillouin Zone edge, which shows a rigid band like energy shift as a function of δ. Transport experiments show that the intrinsic component of the anomalous Hall effect (AHE) is sizable, and undergoes a sign flip across δ. Finally, density functional theory calculations establish a causal link between the observed doping evolution of the band structure and AHE: the AHE sign flip is shown to emerge from the sign change of the Berry curvature, as the semi-metallic band region crosses the Fermi energy. Our findings underscore the increasing relevance of momentum-space Berry curvature in magnetic TMDs and provide a unique platform for intertwining topological physics in real and momentum spaces.