bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age-related changes in the activation timing of postural muscles to the prime mover muscle for bilateral arm flexion during standing
Authors: Kiyota Takeo , Fujiwara Katsuo 
Published: May 2022

Abstract
Background
We aimed to obtain the standard values of age-related changes in the activation timing of postural muscles to the prime mover muscle (anterior deltoid [AD]) for bilateral arm flexion during standing.

Methods
The study participants were 276 children (aged 3–14 years) and 32 adults (aged 20–26 years). In response to a visual stimulus, participants raised both arms from a fully extended position as quickly as possible, stopped their arms voluntarily at a horizontal level at the shoulder, and maintained that position for 2 s. Ten test trials were performed. By using surface electromyography, the duration from the burst onset of the postural muscles to that of AD was measured as the starting time of the postural muscles (rectus abdominis [RA], erector spinae [ES], rectus femoris [RF], biceps femoris [BF], tibialis anterior [TA], gastrocnemius medialis [GcM], and soleus [SOL]). The starting time was presented as a negative value when the burst onset of the postural muscles preceded that of AD, which was defined as the preceding activation. A positive value for the starting time was defined as delayed activation.

Results
In adults, the burst onsets of ES and BF significantly preceded that of AD. In ES, the starting time preceded the onset of AD in those aged ≥ 5–6 years; no difference with adults was found at age 13–14 years. On the other hand, in BF, significant delayed activation was found at ages 3–4 to 11–12 years. While the starting time decreased with age, no significant preceding activation similar to adults was found, even at age 13–14 years. In TA, no significant difference with the onset of AD was found at age 3–6 years, and significant delayed activation was found at age ≥ 7–8 years. Significant delayed activation in GcM, SOL, RA, and RF was observed in all age groups, and no age-related changes were observed in children.

Conclusion
These findings could provide standard values from childhood to adolescence for age-related changes in anticipatory postural muscle activity during voluntary movement while standing and contribute to applications in the fields of sports and rehabilitation.
Feasibility study on calculating the Q value of shallow media by using a dense seismic array and a large-volume airgun source
Authors: Du Shen , Yu YanXiang , Xiao Liang 
Published: May 2022

AbstractThe feasibility of using a dense seismic array with an airgun source to study the quality factors of shallow media is verified. Data were obtained from 37 stations in the dense seismic array located in Binchuan, Yunnan Province, China, and the amplitude–distance attenuation method and the coda normalization method were applied to calculate the S-wave quality factors in the area. The amplitude–distance attenuation method yielded $${Q}_{s}^{-1}$$

Q

s

-
1

=0.0260 $$\pm$$
±
0.0103, and the frequency-dependent $${Q}_{s}^{-1}$$

Q

s

-
1

calculated by the coda normalization method can be expressed by the power law $${Q}_{s}^{-1}(f)\cong 0.0554{f}^{-0.5643}$$

Q

s

-
1

(
f
)

≅
0.0554

f

-
0.5643

. The consistency between the results of these two methods shows that a dense seismic array with an airgun source can be used to study the attenuation characteristics of shallow media. The amplitudes at some points deviate substantially from the fitted curve and thus have a certain influence on the fitting results; hence, we must select high-precision data for the calculation. Given the topography, we speculate that the anomalous stations located on the edge of the Binchuan Basin and in the western hilly area are due to the edge effect of the basin and the weak attenuation of the hilly area and that the anomalous station located in the northern Binchuan depocenter is attributable to local site factors. Compared with the $${Q}_{s}^{-1}$$

Q

s

-
1

estimated by previous studies, the $${Q}_{s}^{-1}$$

Q

s

-
1

in the Binchuan area is found to lie between those of the hard soil and sedimentary rock and is similar to the $${Q}_{s}^{-1}$$

Q

s

-
1

in the North China Basin, corresponding to the shallow velocity structure in this area.
Graphical Abstract
A novel gene from the acidophilic bacterium Leptospirillum sp. CF-1 and its role in oxidative stress and chromate tolerance
Authors: Javier Rivera-Araya , Matías Riveros , Alonso Ferrer , Renato Chávez , Gloria Levicán 
Published: May 2022

AbstractBackgroundAcidophilic microorganisms likeLeptospirillumsp. CF-1 thrive in environments with extremely low pH and high concentrations of dissolved heavy metals that can induce the generation of reactive oxygen species (ROS). Several hypothetical genes and proteins fromLeptospirillumsp. CF-1 are known to be up-regulated under oxidative stress conditions.ResultsIn the present work, the function of hypothetical gene ABH19_09590 fromLeptospirillumsp. CF-1 was studied. Heterologous expression of this gene inEscherichia coli led to an increase in the ability to grow under oxidant conditions with 5 mM K2CrO4or 5 mM H2O2. Similarly, a significant reduction in ROS production inE. colitransformed with a plasmid carrying ABH19_09590 was observed after exposure to these oxidative stress elicitors for 30 min, compared to a strain complemented with the empty vector. A co-transcriptional study using RT-PCR showed that ABH19_09590 is contained in an operon, here named the “och” operon, that also contains ABH19_09585, ABH19_09595 and ABH19_09600 genes. The expression of theochoperon was significantly up-regulated inLeptospirillumsp. CF-1 exposed to 5 mM K2CrO4for 15 and 30 min. Genes of this operon potentially encode a NADH:ubiquinone oxidoreductase, a CXXC motif-containing protein likely involved in thiol/disulfide exchange, a hypothetical protein, and a di-hydroxy-acid dehydratase. A comparative genomic analysis revealed that theochoperon is a characteristic genetic determinant of theLeptospirillumgenus that is not present in other acidophiles.ConclusionsAltogether, these results suggest that theochoperon plays a protective role against chromate and hydrogen peroxide and is an important mechanism required to face polyextremophilic conditions in acid environments.
Long-term patterns of an interconnected core marine microbiota
Authors: Krabberød Anders K. , Deutschmann Ina M. , Bjorbækmo Marit F. M. , Balagué Vanessa , Giner Caterina R. , Ferrera Isabel , Garcés Esther , Massana Ramon , Gasol Josep M. , Logares Ramiro 
Published: May 2022

AbstractBackgroundOcean microbes constitute ~ 70% of the marine biomass, are responsible for ~ 50% of the Earth’s primary production and are crucial for global biogeochemical cycles. Marine microbiotas include core taxa that are usually key for ecosystem function. Despite their importance, core marine microbes are relatively unknown, which reflects the lack of consensus on how to identify them. So far, most core microbiotas have been defined based on species occurrence and abundance. Yet, species interactions are also important to identify core microbes, as communities include interacting species. Here, we investigate interconnected bacteria and small protists of the core pelagic microbiota populating a long-term marine-coastal observatory in the Mediterranean Sea over a decade.ResultsCore microbes were defined as those present in > 30% of the monthly samples over 10 years, with the strongest associations. The core microbiota included 259 Operational Taxonomic Units (OTUs) including 182 bacteria, 77 protists, and 1411 strong and mostly positive (~ 95%) associations. Core bacteria tended to be associated with other bacteria, while core protists tended to be associated with bacteria. The richness and abundance of core OTUs varied annually, decreasing in stratified warmers waters and increasing in colder mixed waters. Most core OTUs had a preference for one season, mostly winter, which featured subnetworks with the highest connectivity. Groups of highly associated taxa tended to include protists and bacteria with predominance in the same season, particularly winter. A group of 13 highly-connected hub-OTUs, with potentially important ecological roles dominated in winter and spring. Similarly, 18 connector OTUs with a low degree but high centrality were mostly associated with summer or autumn and may represent transitions between seasonal communities.ConclusionsWe found a relatively small and dynamic interconnected core microbiota in a model temperate marine-coastal site, with potential interactions being more deterministic in winter than in other seasons. These core microbes would be essential for the functioning of this ecosystem over the year. Other non-core taxa may also carry out important functions but would be redundant and non-essential. Our work contributes to the understanding of the dynamics and potential interactions of core microbes possibly sustaining ocean ecosystem function.
Glycyrrhiza uralensis Fisch. Root-associated microbiota: the multifaceted hubs associated with environmental factors, growth status and accumulation of secondary metabolites
Authors: Chen Chaoyun , Zhong Chaofang , Gao Xi , Tan Chongyang , Bai Hong , Ning Kang 
Published: May 2022

AbstractGlycyrrhiza uralensis Fisch. is an important, perennial medicinal plant whose root microbiome is considered to play an important role in promoting accumulation of effective medicinal ingredients (liquiritin and glycrrhizic acid). Here, we report a comprehensive analysis of the microbial community structural composition and metabolite-plant-microbes association of G. uralensis Fisch. We collected both soil and rhizosphere samples of G. uralensis from different environmental conditions (cultivated and wild) and growth years (grown for one year and three years). Our data revealed higher species diversity in the wild group than in the cultivated group. The core rhizosphere microbiome of G. uralensis comprised 78 genera, including Bacillus, Pseudomonas, Rhizobium, some of which were potential plant beneficial microbes. Our results suggest that the growth of G. uralensis has a correlation with the root-associated microbiota assemblage. Integrated analysis among rhizosphere microbial taxa, plant gene expressions, and liquiritin and glycrrhizic acid accumulation showed that the liquiritin and glycrrhizic acid accumulation exhibited associations with the rhizosphere microbial composition at the genus level. The results provide valuable information to guide cultivation of G. uralensis, and potentially to harness the power of the root-associated microbiota to improve medicinal plant production.
Health systems strengthening interventions for perinatal common mental disorders and experiences of domestic violence in Cape Town, South Africa: protocol for a pilot implementation study
Authors: Abrahams Zulfa , Schneider Marguerite , Honikman Simone , Olckers Patti , Boisits Sonet , Seward Nadine , Lund Crick 
Published: May 2022

Abstract
Background
During the perinatal period, common mental disorders (CMDs) such as depression and anxiety are highly prevalent, especially in low-resource settings, and are associated with domestic violence, poverty, and food insecurity. Perinatal CMDs have been associated with several adverse maternal and child outcomes. While the Department of Health in South Africa provides healthcare workers with the tools to detect psychological distress and experiences of domestic violence, few healthcare workers routinely screen pregnant women at clinic visits, citing discomfort with mental health issues and the lack of standardised referral pathways as the key barriers. The aim of this study is to select and evaluate a set of health systems strengthening (HSS) interventions aimed at improving the care and outcomes for perinatal women with CMDs and experiences of domestic violence, attending public healthcare facilities in Cape Town.

Methods
This study consists of a pre-implementation, development, and implementation phase. Contextual barriers identified during the pre-implementation phase included poor patient knowledge and health-seeking behaviour, high levels of stigma, and poor detection, referral, and treatment rates. Implementation science determinant frameworks were applied to findings from the pre-implementation phase to identify determinants and gaps in delivering high-quality evidence-informed care. A participatory Theory of Change workshop was used to design a HSS programme, consisting of awareness raising, detection, referral, and treatment. HSS interventions selected to support the delivery of the HSS programme includes training, health promotion, change to the healthcare environment, task-sharing, audit and feedback, and performance monitoring. The implementation phase will be used to assess several implementation and clinical outcomes associated with the delivery of the HSS programme, which will be piloted at three healthcare facilities. Qualitative and quantitative methods will be used to evaluate the implementation and clinical outcomes.

Discussion
This pilot implementation study will inform us about a range of implementation and clinical outcome measures that are relevant for assessing HSS interventions for perinatal women with depression, anxiety, or experiences of domestic violence in low-resource settings. Lessons learnt from the pilot study will be incorporated into the design of a cluster randomised control trial for which further funding will be sought.
Digital adoption and efficiency in the maritime industry
Authors: Gavalas Dimitris , Syriopoulos Theodoros , Roumpis Efthimios 
Published: May 2022

AbstractThe COVID-19 pandemic has augmented pre-existing digitalization and environmental trends. In the maritime industry, one of the marked impacts of the pandemic is how the regard for technology has changed. There is now greater appetite and acceptance of digital solutions across the industry. This study investigates the ways the adoption of a series of digital technologies impact shipping firms’ efficiency, that will shed light on how industry stakeholders may derive value from data solutions, for making better operational decisions. We use cross-country firm-level data to evaluate the efficiency effects of maritime industry-level digital adoption. The results provide robust proof that working in a digitalized ecosystem is a way to promote efficiency, though not to the same extent across shipping firms and divisions. Impacts are relatively stronger in water transport activities than warehousing/support activities for transportation. Digital technologies may add to the growing diffusion in efficiency across shipping firms.
Recovery of ro-pax ferry traffic from covid-19 under tightening environmental regulations: case Helsinki-Tallinn
Authors: Tapaninen Ulla , Palu Riina 
Published: May 2022

AbstractIn 2020, the number of passengers on international ro-pax ferries collapsed due to the pandemic caused by the Covid-19 virus and subsequent travel restrictions. At the same time, both the International Maritime Organisation and the European Union are setting stringent regulations on carbon dioxide emissions from ships. In this research, we look at what options companies offering ro-pax services have to recover from the Covid-19 pandemic under-tightening environmental regulations and the future options for the industry. The case under study is ro-pax ferry traffic between Helsinki and Tallinn. It is one of the busiest international passenger ferry connections in the world. The economics of transport are based on large high-speed vessels, the combination of passengers and cargo, and sales onboard. We created four scenarios for the traffic: to continue the same high-speed ro-pax system as in 2019, to reduce the number of vessels, to switch to new types of ships, to slow down the speed of the vessels or to divide traffic into faster and slower ships. The research contributes to discussion of competitive strengths of ro-pax transport.
The effectiveness of improving healthcare teams’ human factor skills using simulation-based training: a systematic review
Authors: Abildgren Lotte , Lebahn-Hadidi Malte , Mogensen Christian Backer , Toft Palle , Nielsen Anders Bo , Frandsen Tove Faber , Steffensen Sune Vork , Hounsgaard Lise 
Published: May 2022

AbstractBackgroundSimulation-based training used to train healthcare teams’ skills and improve clinical practice has evolved in recent decades. While it is evident that technical skills training is beneficial, the potential of human factor training has not been described to the same extent. Research on human factor training has been limited to marginal and acute care scenarios and often to validate instruments. This systematic review aimed to investigate the effectiveness of simulation-based training in improving in-hospital qualified healthcare teams’ human factor skills.MethodA review protocol outlining the study was registered in PROSPERO. Using the PRISMA guidelines, the systematic search was conducted on September 28th, 2021, in eight major scientific databases. Three independent reviewers assessed title and abstract screening; full texts were evaluated by one reviewer. Content analysis was used to evaluate the evidence from the included studies.ResultsThe search yielded 19,767 studies, of which 72 were included. The included studies were published between 2004 and 2021 and covered research from seven different in-hospital medical specialisms. Studies applied a wide range of assessment tools, which made it challenging to compare the effectiveness of human factor skills training across studies. The content analysis identified evidence for the effectiveness. Four recurring themes were identified: (1) Training human factor skills in qualified healthcare teams; (2) assessment of human factor skills; (3) combined teaching methods, and (4) retention and transfer of human factor skills. Unfortunately, the human factor skills assessments are variable in the literature, affecting the power of the result.ConclusionSimulation-based training is a successful learning tool to improve qualified healthcare teams’ human factor skills. Human factor skills are not innate and appear to be trainable similar to technical skills, based on the findings of this review. Moreover, research on retention and transfer is insufficient. Further, research on the retention and transfer of human factor skills from simulation-based training to clinical practice is essential to gain knowledge of the effect on patient safety.
Dimensional variability characterization of additively manufactured lattice coupons
Authors: Snodderly Kirstie Lane , Fogarasi Magdalene , Badhe Yutika , Parikh Ankit , Porter Daniel , Burchi Albert , Gilmour Laura , Di Prima Matthew 
Published: May 2022

Abstract
Background
Additive manufacturing (AM), commonly called 3D Printing (3DP), for medical devices is growing in popularity due to the technology’s ability to create complex geometries and patient-matched products. However, due to the process variabilities which can exist between 3DP systems, manufacturer workflows, and digital conversions, there may be variabilities among 3DP parts or between design files and final manufactured products. The overall goal of this project is to determine the dimensional variability of commercially obtained 3DP titanium lattice-containing test coupons and compare it to the original design files.

Methods
This manuscript outlines the procedure used to measure dimensional variability of 3D Printed lattice coupons and analyze the differences in external dimensions and pore area when using laser and electron beam fabricated samples. The key dimensions measured were the bulk length, width, and depth using calipers. Strut thickness and pore area were assessed for the lattice components using optical imaging and µCT.

Results
Results show a difference in dimensional measurement between printed parts and the computer-designed files for all groups analyzed including the internal lattice dimensions. Measurements of laser manufactured coupons varied from the nominal by less than 0.2 mm and results show averages greater than the nominal value for length, width, and depth dimensions. Measurements of Electron Beam Melting coupons varied between 0.4 mm-0.7 mm from the nominal value and showed average lengths below the nominal dimension while the width and depths were greater than the nominal values. The length dimensions of Laser Powder Bed Fusion samples appeared to be impacted by hot isostatic press more than the width and depth dimension. When lattice relative density was varied, there appeared to be little impact on the external dimensional variability for the as-printed state.

Conclusions
Based on these results, we can conclude that there are relevant variations between designed files and printed parts. However, we cannot currently state if these results are clinically relevant and further testing needs to be conducted to apply these results to real-world situations.
Prior experience with target encounter affects attention allocation and prospective memory performance
Authors: Moore Kara N. , Lampinen James Michael , Adams Eryn J. , Nesmith Blake L. , Burch Presley 
Published: May 2022

AbstractWe examined how prior experience encountering targets affected attention allocation and event-based prospective memory. Participants performed four color match task blocks with a difficult, but specified prospective memory task (Experiment 1) or an easier, but unspecified prospective memory task (Experiment 2). Participants were instructed to search for targets on each block. Participants in the prior experience condition saw targets on each block, participants in the no prior experience condition only saw targets on the fourth block, and, in Experiment 2, participants in the mixed prior experience condition encountered some of the targets on the first three blocks, and saw all the targets on the fourth block. In Experiment 1, participants in the no prior experience condition were less accurate at recognizing targets and quicker to respond on ongoing task trials than participants in the prior experience condition. In Experiment 2, we replicated the effect of prior experience on target accuracy, but there was no effect on ongoing trial response time. The mixed experience condition did not vary from the other conditions on either dependent variable, but their target accuracy varied in accordance with their experience. These findings demonstrate that prospective memory performance is influenced by experience with related tasks, thus extending our understanding of the dynamic nature of search efforts across related prospective memory tasks. This research has implications for understanding prospective memory in applied settings where targets do not reliably occur such as baggage screenings and missing person searches.
Icon arrays reduce concern over COVID-19 vaccine side effects: a randomized control study
Authors: Fansher Madison , Adkins Tyler J. , Lalwani Poortata , Boduroglu Aysecan , Carlson Madison , Quirk Madelyn , Lewis Richard L. , Shah Priti , Zhang Han , Jonides John 
Published: May 2022

AbstractOn April 13, 2021, the CDC announced that the administration of Johnson and Johnson’s COVID-19 vaccine would be paused due to a rare blood clotting side effect in ~ 0.0001% of people given the vaccine. Most people who are hesitant to get a COVID-19 vaccine list potential side effects as their main concern (PEW, 2021); thus, it is likely that this announcement increased vaccine hesitancy among the American public. Two days after the CDC’s announcement, we administered a survey to a group of 2,046 Americans to assess their changes in attitudes toward COVID-19 vaccines. The aim of this study was to investigate whether viewing icon arrays of side effect risk would prevent increases in COVID-19 vaccine hesitancy due to the announcement. We found that using icon arrays to illustrate the small chance of experiencing the blood clotting side effect significantly prevented increases in aversion toward the Johnson and Johnson vaccine as well as all other COVID-19 vaccines.