bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uterine Contractile Activity and Abortifacient Effect of the Aqueous Extract of Euphorbia heterophylla L. Leaves in Albino Rats
Authors: Elemo Olubunmi O. , Akinyede Akinwunmi A. , Oreagba Ibrahim  A. , Nicholas-Okpara Viola A. , Unuofin Jeremiah O. 
Published: January 2022

Background and Purpose: Euphorbia heterophylla Linn. (Euphorbiaceae) is a promising medicinal plant used as an oxytocic in folkloric medicine. The study investigated the uterotonic and abortifacient effects of the aqueous leaf extract of Euphorbia heterophylla (AEEH).
Methods: GC-MS analysis of AEEH was done. In vitro experiment on the contractile activity of AEEH was conducted on the uterus of nulliparous female Sprague Dawley rats using an isolated organ bath. The abortifacient activity of the extract was determined in pregnant rats orally administered 50, 100, 200, and 400 mg/kg AEEH for five consecutive days.
Results: GC-MS analysis of AEEH revealed high amounts of 1-butanol 3-methyl acetate, benzofuran,2,3-dihydro-, 2-methoxy-4-vinyl phenol, and sucrose. Some of the classes of compounds identified in the extract such as phenols, terpenoids, fatty acids, aldehydes, steroid, and glucoside have been associated with uterotonic and abortifacient properties. The extract (0.125-4 mg/mL) was able to enhance the contractile activity of uterine smooth muscles (EC50 = 3.39 × 10-1 mg/mL) similar to oxytocin (EC50 = 3.99 × 10-4 mg/mL) and acetylcholine (EC50=2.68 × 10-4 mg/mL). Pre-treatment with salbutamol, indomethacin, and stimulation in a calcium-deprived medium significantly (P<0.0001) reduced uterine contractions induced by cumulative concentrations of the aqueous extract. However, there was no significant change in uterine contraction in tissues pre-treated with atropine. The aqueous extract induced abortion in 50%, and 83.33% of the animals at 200, and 400 mg/kg respectively when orally administered to pregnant rats for five days.
Conclusions: This study demonstrates the uterotonic and abortifacient effects of AEEH and supports the ethnomedicinal use of the plant as an oxytocic.
Achloride bread enriched with ɷ-3 fatty acids and dietary fibers
Authors: Юдина Тамара Алексеевна , Кандроков Роман Хажсетович , Матюнина Александра Владимировна , Зайцева Лариса Валентиновна 
Published: January 2022

Разработана рецептура обогащенного ахлоридного хлеба с добавлением муки чиа и заменителя молочного жира (1,7 г омега-3 жирных кислот/100 г) совместно с подсолнечным маслом (соотношение 55:45) в количестве 1-2,5 % и 4,5 %, соответственно, от массы пшеничной муки. При внесении муки чиа не менее 1 % получен хлеб с содержанием омега-3 жирных кислот более 0,2 г/100 г и пищевых волокон более 3 г/100 г, что позволяет маркировать его, в соответствии с действующим законодательством, как «источник» этих нутриентов. При внесении муки чиа не менее 2,5 % получен хлеб с содержанием омега-3 жирных кислот более 0,4 г/100 г и пищевых волокон более 6 г/100 г, являющийся, в соответствии с действующим законодательством, продуктом «с высоким содержанием» этих нутриентов. Соотношение насыщенных жирных кислот к ненасыщенным в жировой фазе хлеба составляло 1:(2,5-3), при этом содержание полиненасыщенных жирных кислот составляло 46,9-52,3 % от суммы всех жирных кислот, что соответствует рекомендациям ВОЗ. Соотношение между омега-3 и омега-6 жирными кислотами в жировой фазе хлеба соответствовало рекомендациям российских ученых и составляло 1:(3,7-6). По физико-химическим и органолептическим характеристикам разработанный ахлоридный хлеб соответствовал нормативной документации. Обогащение ахлоридного хлеба дефицитными омега-3 и омега-6 жирными кислотами и пищевыми волокнами способствует его целевому назначению - профилактике сердечно-сосудистых заболеваний.
A recipe has been developed for enriched achloride bread with the addition of chia flour and milk fat substitute (1.7 g of omega-3 fatty acids /100 g) together with sunflower oil (ratio 55:45) in the amount of 1-2.5 % and 4.5 %, respectively, from the mass of wheat flour. When chia flour was added at least 1 %, bread was obtained with an omega-3 fatty acid content of more than 0.2 g/100 g and dietary fiber more than 3 g/100 g, which allows it to be labeled in accordance with current legislation as a «source» of these nutrients. When chia flour was added at least 2.5 %, bread was obtained with an omega-3 fatty acid content of more than 0.4 g/100 g and dietary fiber more than 6 g /100 g, which, in accordance with the current legislation, is a product «with a high content» of these nutrients. The ratio of saturated to unsaturated fatty acids in the fatty phase of bread was 1:(2.5-3), while the content of polyunsaturated fatty acids was 46.9-52.3 % of the total fatty acids, which is in line with the WHO recommendations. The ratio between omega-3 and omega-6 fatty acids in the fat phase of bread corresponded to the recommendations of Russian scientists and was 1:(3.7-6). In terms of physicochemical and organoleptic characteristics, the developed achloride bread corresponded to the normative documentation. Enrichment of achloride bread with deficient omega-3 fatty acids and dietary fiber contributes to its intended purpose - the prevention of cardiovascular diseases.
URDU21-Historical Study of Hamd-Nigari in Saraiki Language Saraiki
Authors: Rind Dr Ayaz Ahmad , Fiaz Hafiz Muhammad , Asghar Maqsoom 
Published: January 2022

This research paper explains the style of praise of the Allah Almighty which has been written mainly in Saraiki language. Praise here means praise of Allah Almighty. Allah created every living soul in this universe. Man, as the noblest of creatures, giving thanks to Allah, and praises Allah, is called Hamd. Saraiki Waseeb is traditionally called Indus Valley. The language of this region is Saraiki. It is very widespread languages are prominent. Man has always thought that there is a being far beyond his reach and that he is the one who created the universe. His power is omnipotent, even if it is human intent. Man must have had a relationship with his God in one way or another, whether it was arson or idolatry. Man praised his own God in his own way. We find the ancient literature of Saraiki language mostly in poetry in which the poetic genres like Hamd, Mawlood, Naat, Haliya Mubarak, Noornameh, Mirajnameh, Toldnameh, Hudhdnameh, Wasitnameh, Marsiya Nigari are prominent. In which poets have expressed their religious sentiments with great love. There are many forms of this belief but its background is the same which is the concept of one God.
Étnico-racial, o gênero e a segurança pública: apontamentos para uma investigação acadêmica
Authors: Miranda José , Mateus Santos Diego 
Published: January 2022

O artigo apresenta bases epistemológicas sobre temas relativos aos ao étnico-racial, o gênero e a segurança pública, a partir da intersecionalidade e dos direitos humanos. As problemáticas suscitadas pelas temáticas são interdisciplinares e pensadas de forma transdisciplinares, sob a perspectiva dos grupos vulneráveis. Os atravessamentos temáticos ocorrem por descrever questões complexas e implicadas por raça, gênero e violência. Essas mesmas questões requerem um ‘olhar’ no qual variáveis precisam ser colocadas lado a lado e simultaneamente para verificação de sua força no processo de sujeição ou de emancipação nos corpos dos agentes sociais. É uma pesquisa qualitativa e bibliográfica, neste sentido, utiliza a praxeologia, abordagem que compatibiliza ideias estruturalistas e construtivistas, para isso, separa as representações do senso comum para demarcar as estruturas objetivas, o campo; em seguida, realça a experiencia imediata dos agentes pela noção de habitus. Portanto, o debate epistêmico sobre o étnico-racial, o gênero e a segurança a partir dos atravessamentos e da intersecionalidade possibilitam pluralidades investigativas bibliográficas e empíricas na premissa do desvelamento das relações de dominação, subalternidade, violência e racismo.
Edukasi Metode Be-Fast Guna Meningkatkan Self Awareness Terhadap Deteksi Dini Stroke
Authors: Simanjuntak Galvani Volta , Pardede Jek Amidos , Sinaga Janno 
Published: January 2022

Hipertensi merupakan faktor pencetus terjadinya stroke. Menumbuhkan kesadaran dan kewaspadaan diri sangat penting dalam upaya pencegahan terjadinya komplikasi suatu penyakit. Self awareness mengenai pentingnya melakukan deteksi dini dapat menjadi upaya untuk mengurangi risiko terjadinya stroke pada orang yang menderita hipertensi. Salah satu metode deteksi dini untuk penderita stroke adalah metode BE-FAST. Metode BE-FAST adalah Balance (keluhan kehilangan keseimbangan atau pusing atau kepala yang berat sehingga cenderung berpegangan pada sesuatu atau duduk Kegiatan pengabdian masyakat ini dilakukan dalam bentuk promosi kesehatan melalui edukasi tentang BE-FAST yang disampaikan dengan metode ceramahbertujuan untuk meningkatkan self awareness terhadap deteksi dini stroke pada penyandang hipertensi. Kegiatan ini dihadiri diikuti 27 peserta. Hasil evaluasi menunjukkan bahwa rata-rata jawaban benar peserta meningkat dari sebelum edukasi rata-rata 4 meningkat menjadi 8 setelah edukasi. Dengan meningkatnya pengetahuan, diharapkan penyandang hipertensi memiliki self awareness yang tinggi terhadap deteksi dini guna menurunkan risiko terjadinya stroke.
Unrecognized Diaphragm Hernia
Authors: Elhattabi Khalid , Benghait Hasna , Essaidi Zakaria , Elbakouri Abdelilah , Bouali Mounir , Bensardi Fatimazahra , Fadil Abdelaziz 
Published: January 2022

Introduction: Post-traumatic diaphragmatic hernia is defined as the passage of abdominal viscera into the thorax through a post-traumatic diaphragmatic breach. They are rare and may be unrecognized in 10-30% of cases at initial management.
Materials and Methods: A retrospective descriptive study including all the patients taken in charge for post-traumatic neglected diaphragmatic lesions over two years between December 2018 and January 2021 within the service of visceral emergencies of the universitary hospital center Ibn Rochd of Casablanca. Our work aims to define the epidemiological, clinical, and therapeutic characteristics of patients admitted for post-traumatic diaphragmatic lesions.
Results: The average age of the patients was 30 years (range 18 to 43 years). All patients were male. They were due to a closed trauma in 11 patients (32%) and a penetrating trauma in 58%. The diagnosis was guided preoperatively by the different imaging techniques, in particular chest radiography and CT scan. Treatment was mainly by laparotomy and consisted of closure of the diaphragmatic breach by simple sutures.
Conclusion: Post-traumatic diaphragmatic hernias can go unnoticed and can be life-threatening in case of associated lesions or complications.
Frequency of Hypocalcaemia among Children (Age 2-60 Months) Presenting with First Episode of Afebrile Seizures: A Cross Sectional Study
Authors: Asadullah . , Shaikh Salma , Farhat Ayesha , Amanullah . , Memon Sehrish , Chohan Muhammad Nadeem 
Published: January 2022

Aim: To determine the frequency of hypocalcaemia among children aged 2 to 60 months presenting with afebrile seizures.
Study Design: A cross sectional study.
Place and Duration: Department of Pediatrics, Liaquat University of medical and Health Sciences Jamshoro, from February to August-2020.
Methodology: A total of 130 children aged 2 to 60 months, having afebrile fits with birth weight more than 2.5 kg were enrolled. After taking full history, detailed examination was done. Two ml blood sample was taken from each patient and was sent to diagnostic laboratory of the institution to find out calcium levels. In case of proven hypocalcaemia, injection calcium gluconate 100 mg/kg was administered. Mean and standard deviation were calculated for quantitative variables while frequency and percentages were noted for qualitative variables. Frequency of hypocalcaemia was recorded and study variables were compared between children with and without hypocalcaemia.
Results: Majority of the patients, 69 (53.1%) were male, 64 (49.2%) less than or equal to 12 months of age, 28 (21.5%) had maternal educational status as illiterate, 78 (60.0%) belonged to rural areas, 59 (45.4%) belonged to middle socioeconomic status, 69 (53.1%) had poor exposure to sunlight, 80 (61.5%) had malnutrition, 82 (63.1%) had child spacing of less than 2 years, 79 (60.8%) with less than 5 episodes of fits per day and 88 (67.7%) had duration of fits per day as less than 5 minutes. Frequency of hypocalcaemia was noted in 81 (62.3%) cases.
Conclusion: We concluded that hypocalcaemia is the frequent cause of afebrile seizures in children aged 2 to 60 months.
Comparison between Study of Bone Mineral Density in Males and Females of Various Age Groups
Authors: Sawal Anupama , Thute Preeti , Withale Deepali , Yadgire Geetanjali 
Published: January 2022

Background: Osteoporosis is one of the complex diseases which have multiple etiology. The cause of it is maybe genetic and environmental or nutritional. There are various techniques for the measurement of bone mineral density. The DXA (DUEL ENERGY X-RAY ABSORBTIOMETRY AND BONE DENSITOMETER) is frequently used to measure bone mineral density. The other measures to measure bone mineral density are Quantitative computed
Results: With the increase in negative T tomography and ultrasound tonometry. The WHO standard for distinguishing patients as normal with 1 standard deviation of peak bone mass. Osteopinic 1 to 2.5 below peak bone mass .osteoporotic ;>2.5 standard deviation below peak bone mass.
Materials and Methods: The study included 200 Subjects of various age groups of both sexes. The study was carried out in the department of anatomy with the collaboration of the Department Of Orthopedics. The proforma was structured to include the details of the subjects with height, weight, etc. With a score of one, the risk of fracture increased 1.5 to 3 fold.
Conclusion: The study of Bone Mineral Density (BMD) can help in increasing awareness about bone health in growing countries. There is a significant association between various age groups and a non-significant association between genders for BMD evaluation.
The current study puts up to our understanding of BMD disparities among people that would suggest the use of local testimonial scales for an authentic explanation of BMD reports.
Awareness of Dry Eyes Disease among Dental Students - A Survey
Authors: Abinaya S. , Sinduja Palati , Priyadarshini R. 
Published: January 2022

Introduction: Dry eye is a common condition that affects 85 percent of adult students worldwide, has no effective treatment, and results in significant loss of productivity at work.
Aim: This study aims to assess the knowledge and awareness of dental students about dry eye disease.
Materials and Methods: An online google form was used to distribute a questionnaire based study with 12 questions to 100 people. The study began with the participants being briefed on the trial's details. The study used a 100-person sample size. The information was gathered and statistically examined.
Results: In this study, 96% of the students were aware that lack of sleep causes Dry Eyes Disease and 4% of the students were unaware of it. Around 83% of the students were aware that dry eye is reversible and 17% of the students were not aware of it. The overall result was positive, most of them were aware of the dry eye disease. This proves an outright positive result.
Conclusion: The present study shows that the students under 75% were aware of Dry Eyes Disease but 25% were unaware of dry eye disease. There is no sufficient awareness among dental students. So, by this survey, we create more awareness among dental students.
Opportunistic Infections Due to Overuse of Steroids
Authors: Khan Ovais , Jadhav Ulhas 
Published: January 2022

Background: Case reviews of rhino-orbital mucormycosis in sufferers with coronavirus sickness 2019 (COVID-19) are at the rise, specifically in India. Diabetes mellitus (DM) is a chance aspect for excessive COVID-19 and mucormycosis on its own. The purpose of this is to carry out a scientific review of the literature to decide the capabilities of Opportunistic Infections due to overuse of steroid.
Methods: Using key phrases like COVID 19, Mucormycosis, Mucor, Novel corona virus, and SARS CoV-2, a scientific review was carried out on the subsequent databases: PubMed, Google Scholar, and Cochrane Library.
Results: Increased mucormycosis in India seems to be the end result of an unholy trinity of diabetes (excessive genetic occurrence), immoderate corticosteroid utilization (will increase blood glucose and results in opportunistic fungal contamination), and COVID-19 (cytokine storm, lymphopenia, endothelial damage). To lower the prevalence of lethal mucormycosis, all efforts must be taken to keep ideal hyperglycaemia, and best careful evidence-primarily based totally use of corticosteroids in sufferers with COVID-19 is suggested. Glucocorticosteroids (GC) play an critical position withinside the remedy of neuro-oncologic patients. GC are used for the control of malignant mind tumour’s, both number one of secondary, neoplastic epidural spinal wire compression (NESC), as adjuvant chemotherapy of a few relevant worried device tumours and perioperatively in mind surgery. GC are believed to exert their effect on mind tumours especially through decreasing the tumor-related vasogenic edema, in all likelihood through lowering the extended capillary permeability of the blood-mind barrier (BBB),
Conclusion: Diabetes mellitus seems to result in a vicious cycle of hyperglycaemia and immunosuppression while coupled with the SARS COV 2 Virus and steroid treatment, which could cause excessive fungal colonization like mucormycosis.
Knowledge and Awareness on Tendency of Disease in Different Blood Groups among General Population- A Survey
Authors: Vignesh M. , Sinduja Palati , Priyadharshini R. 
Published: January 2022

Background: Blood groups are classified into two types ABO system and Rh system and ABO system have the antigen on the RBC and the antibody of the blood and whereas Rh blood system only contain the only antigen called D antigen that is present on the surface of RBC and the criteria to find the Rh+ or Rh- is by presence or absence of D antigen and this is the prime understanding of the blood groups where the antigen, antibody and cellular units together comprise the host response to the antigen or disease and enhance it. Our study is to create the awareness among the people for different blood groups disease-causing tendency
Materials And Methods: The questionnaire was made comprising of 15 questions using google forms and it is circulated among 100 peoples and the data was collected and evaluated by Chi-square test using SPSS VERSION 26. (p<0.005)
Results: The results showed that more than 75% of the study population are unaware of the blood groups associated with systemic illness and further survey is needed to analyze more population.
Conclusion: From the results, we concluded that certain programs and initiatives are needed to overcome the disease caused by the blood groups and our study focuses mainly on improving the knowledge of the individual about the knowledge and awareness of disease in blood groups.
An Association between Diabetes and COVID-19 Patients: A Brief Overview
Authors: Parmita Pragyna , Ghodmare Reema 
Published: January 2022

Coronavirus disease, a pandemic (COVID19), an illness caused by the severe acute respiratory syndrome Coronavirus 2 (SARSCoV2), is triggering significant illness and death. The current coronavirus disease SARSCoV2 2019 (COVID19) pandemic is a certain challenge for patients with diabetes. Advanced phase and the occurrence of diabetes mellitus, high blood pressure, and obesity rise the threat of hospitalization and contribute to the sternness and death of patients with COVID19. Furthermore, it further exacerbate the clinical consequences for those patients with diabetes who often suffer from comorbidities. In infectious diseases blood sugar control is often suboptimal, and Insulin therapy and Anti-diabetic drugs must be adjusted consequently. On the other hand, diabetic patient’s accessibility to the outpatient clinics is limited during the current season in order to advise on unconventional treatment options, in particular to the implementation of new telemedical strategies. Therefore, the COVID-19 disaster should be used as an opportunity to take a remarkable step in the care of patients with diabetes. COVID19 patients suffering from diabetes are related with a two bend upsurge in death and cruelty of COVID19 matched to people who don’t have diabetes additionally, data suggests that high blood pressure, diabetes and cardiovascular disease are peril factors important for progression and unfavourable of COVID 19 patients. It was a critical obstacle to conduct an examination that should contain numerous intriguing features, like a progressive age, addicted to smoking, and obesity that could possibly alter the deduction depending on the limited number of victims.
Characteristics and outcome of facial nerve palsy from Lyme neuroborreliosis in the United States
Authors: Marques Adriana , Okpali Grace , Liepshutz Kelly , Ortega‐Villa Ana Maria 
Published: January 2022

AbstractObjectivesFacial palsy is the most common manifestation of Lyme neuroborreliosis (LNB) in the United States. This study aimed to describe features of patients with early LNB presenting with facial palsy and to determine if corticosteroids in addition to antibiotic therapy was associated with unfavorable outcome.MethodsRetrospective analysis of participants enrolled in clinical studies investigating Lyme disease (N = 486) identified 44 patients who had facial palsy from LNB. The House–Brackmann scale was used to quantify the facial nerve dysfunction.ResultsMost patients presented in the summer months. Erythema migrans, frequently associated with systemic symptoms, occurred in 29 patients. Thirteen patients presented with bilateral facial palsy, usually with sequential involvement. Fourteen patients had painful radiculopathy. Of the 38 patients treated with antibiotics before the resolution of the palsy who had complete follow‐up, 24 received both antibiotics and corticosteroids. Of these 38 patients, 34 recovered completely, 3 had nearly complete recovery, and 1 had moderate dysfunction. There were no differences between the treatment groups in achieving complete resolution of the palsy at 12 months or in time to complete recovery.InterpretationA history of rash compatible with erythema migrans or febrile illness in the weeks preceding the palsy are helpful clues pointing toward LNB and should be actively sought when evaluating patients with acute‐onset peripheral facial palsy, particularly bilateral facial palsy. Treatment with antibiotic therapy is highly effective and most patients will fully recover facial nerve function. Adjunctive corticosteroid therapy appears to not affect the speed of recovery or overall outcome in this retrospective observational study.