bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing public financing for nutrition in Bhutan, Nepal and Sri Lanka
Authors: Andersen Christopher T. , Cain Jewelwayne S. , Chaudhery Deepika N. , Ghimire Mamata , Higashi Hideki , Tandon Ajay 
Published: March 2022

AbstractThe objective of this study was to assess public financing for nutrition in Bhutan, Nepal and Sri Lanka to identify limitations of available data and to discuss policy implications. A variant of the Scaling Up Nutrition Movement methodology was used. Budget allocations and expenditures for relevant government ministries during 2012–2018 were identified. Nutrition‐related line items were tagged using definitions of nutrition‐specific and nutrition‐sensitive interventions. Data were aggregated by year and calculated in constant United States dollars (USD). Expenditures by year were presented as a proportion of gross domestic product and general government expenditures. The percent utilization of budget allocations and proportion of funding from central government sources were determined. Per capita expenditures on nutrition‐specific interventions varied from USD 1.08–8.76 and for nutrition‐sensitive interventions varied from USD 20.22–51.20. Nutrition‐specific expenditures as a percent of gross domestic product ranged from 0.08% in Sri Lanka in 2017% to 0.34% in Nepal in 2016. The median utilization rate was 64% for nutrition‐specific and 84% for nutrition‐sensitive interventions. Nutrition‐specific funding financed by the central government was 90.7% in Bhutan and 99.4% in Sri Lanka. This study revealed the need to prioritize and invest in evidence‐based interventions, including balancing investments in nutrition‐specific versus ‐sensitive interventions. Challenges in estimation of nutrition expenditures and cross‐country comparison were also observed, highlighting the need for appropriate nutrition line item tagging and standardized systems for data collection.
Global evidence of persistent violations of the International Code of Marketing of Breast‐milk Substitutes: A systematic scoping review
Authors: Becker Genevieve E. , Zambrano Paul , Ching Constance , Cashin Jennifer , Burns Allison , Policarpo Eva , Datu‐Sanguyo Janice , Mathisen Roger 
Published: March 2022

AbstractThe influence of marketing on infant and young child feeding and health is well recognized, and an International Code was adopted by the World Health Assembly (WHA) in 1981 to reduce inappropriate marketing and protect breastfeeding. Yet the marketing and influencing continue. This scoping review systematically examined the published research evidence on the nature and extent of exposure to International Code violations from 1981 to August 2021. We used several search strategies involving multi‐language databases, organization websites, citation tracking, and expert consultation, to find research items meeting our inclusion criteria. We evaluated 657 items and retained 153 studies from at least 95 countries in the review. The majority of the studies (n = 113) documenting exposure to inappropriate marketing were published since 2010. Studies reported a broad range of marketing violations targeting mothers and families, health workers, and the general public. Marketing via digital platforms and brand extension has become more frequent. The evidence shows the use of misleading and inaccurate labeling and health and nutrition claims in breach of the Code. Our review confirms that violations of the Code have not ceased and calls for renewed attention from the WHA and national governments to protect the health of children and their mothers.
Violations of International Code of Breast‐milk Substitutes (BMS) in commercial settings and media in Bangladesh
Authors: Sheikh Sifat P. , Akter Syeda M. , Anne Faugia I. , Ireen Santhia , Escobar‐Alegria Jessica , Kappos Kirsten , Ash Deborah , Rasheed Sabrina 
Published: March 2022

AbstractThe International Code of Marketing of Breast‐milk Substitutes (BMS) instituted to protect breastfeeding against unethical marketing, has been adopted by many countries, including Bangladesh. Despite national adoption, evidence suggests violations occur and inadequate BMS Code implementation is an issue. The study aimed to assess violations of the International BMS Code and the national ‘Breast‐milk Substitutes, Infant Foods, Commercially Manufactured Complementary Foods and the Accessories Thereof (Regulation of Marketing) Act, 2013’ of Bangladesh in commercial settings (retail outlets and media) in Bangladesh, for different types of milk, bottles, and teats using a standardized Network for Global Monitoring and Support for Implementation of the Code and Subsequent relevant World Health Assembly Resolutions (NetCode) protocol. This cross‐sectional quantitative study was conducted in Bangladesh from January to September 2018 in Dhaka, Chattogram, and Sylhet cities. Descriptive statistics were reported and χ2 tests were conducted to assess differences between categorical variables of interest. Data were analysed using SPSS version 20. In retail outlets, there were higher proportion of violations observed in Dhaka than in Sylhet and Chattogram (p < 0.001). Significantly greater proportion of violations in product labels occurred among products sold without local distributors compared to others (p < 0.05); violations were higher among “other milk” for children aged 0 to <36 months compared to formulas and growing‐up milk (p < 0.05). Among media channels, internet clips had significantly higher proportions of violations compared to television, radio and newspaper (p < 0.001). BMS Code violations were prevalent in product labels and promotion of products through retail outlets. The study findings highlight the need for specific multisectoral strategies for better enforcement of BMS Code and points to the need for periodic assessment of Code violations.
Multi‐month time‐lag effects of regional vegetation responses to precipitation in arid and semi‐arid grassland: A case study of Hulunbuir, Inner Mongolia
Authors: Wu Taosuo , Bai Hongmei , Feng Feng , Lin Qian 
Published: March 2022

AbstractThe 16 years of normalized difference vegetation index (NDVI) and precipitation data are used to analyze the time‐lag effects of the growing‐season NDVI response to precipitation at regional scales. This study focuses on the arid and semi‐arid Hulunbuir grassland dominated by perennials in northeast China. The multi‐month time‐lag effects are examined using simple statistical approaches, which can detect the two distinct time‐lags for four subregions with four major land‐cover types. A “positive” time‐lag effect of the growing‐season NDVI response to precipitation is observed at 1‐month (May in the current year) time‐lag and 13‐month (May in the previous year) time‐lag while a “negative” time‐lag effect is observed at 9‐month (September in the previous year) time‐lag. In addition, the prediction results of NDVI based on precipitation indicate that the NDVI prediction model considered the lagged monthly precipitation has good performance. Therefore, revealing the time‐lag effects is very important for accurately predicting the growing‐season NDVI and evaluating the vegetation dynamics.
Citizen involvement in public policy: Does it matter how much is at stake?
Authors: van der Does Ramon 
Published: March 2022

AbstractPublic administrations increasingly try to find new ways to involve citizens in policy‐making. However, many democratic innovations draw in only a fraction of the public. Why? I hypothesize that we observe such low participation rates because there is often not enough at stake for citizens. I test this with a preregistered survey experiment on citizens' intentions to participate in participatory budgets in the Netherlands. I fielded the experiment among a sample of citizens that had just experienced a participatory budget (N = 225) and among a population‐based sample (N = 1369). I operationalized the stakes as the amount of public money about which citizens can decide. The results show that more money generally does not increase citizens' intention to participate. Supplementary analyses confirm the experimental findings and provide reasons how and why the stakes involved (do not) matter for citizens' involvement.
Comparison of Bovine and Carp Fish Visual Pigment Photo‐Intermediates at Room Temperature
Authors: Dhankhar Dinesh , Nagpal Anushka , Tachibanaki Shuji , Li Runze , Cesario Thomas C. , Rentzepis Peter M. 
Published: March 2022

ABSTRACTThis paper presents room temperature nanoseconds to milliseconds time‐resolved spectra and kinetics of the intermediate states and species of bovine and carp fish rhodopsin visual pigments, which also contained ~5% cone pigments. The nanoseconds to milliseconds range cover all the major intermediates in the visual phototransduction process except the formation of bathorhodopsin intermediate which occurs at the femtosecond time scale. The dynamics of these visual pigment intermediates are initiated by excitation with a 532 nm nanosecond laser pulse. The recorded differences between bovine and carp rhodopsin time‐resolved spectra of the formation and decay kinetics of their intermediates are presented and discussed. The data show that the carp samples batho intermediate decays faster, nearly by a factor of three, compared to the bovine samples. The formation and decay spectra and kinetics of rhodopsin outer segments and extracted rhodopsin inserted in buffer solution were found to be identical, with very small differences between them in the decay lifetimes of bathorhodopsin and formation of lumirhodopsin.
The role of species interactions for forest resilience to drought
Authors: Haberstroh S. , Werner C. 
Published: March 2022

ABSTRACTIncreasing durations and frequencies of droughts under climate change endanger the sustainable functioning of forests worldwide. The admixture of species with complementary resource use may increase the resilience of forests towards drought; however, little is known about modifications of species interactions (i.e. facilitation and competition) by increasing drought severity in mixed forests. In particular, knowledge on the regulation of central ecohydrological processes, such as tree water fluxes, is lacking. Therefore, we conducted a literature review to assess the impact of species interactions on tree resilience (resistance + recovery) under increasing drought severity. The classification of studies into three drought classes suggested that beneficial species interactions, i.e. through improved water relations, were prevalent under mild droughts. However, with increasing drought, negative effects, such as interspecific competition, occurred. These negative interactions were prominent under extreme droughts, where even trees with complementary resource‐use strategies competed for water resources. Fewer data are available on recovery of water fluxes. The limited evidence supported the patterns observed for drought resistance, with facilitation and complementarity of species in mixtures enhancing tree recovery after moderate droughts. However, after extreme droughts, competition effects and reduced recovery for some species were observed, which can strongly compromise tree resilience. While we acknowledge the importance of mixed forests for biodiversity, ecosystem services or pest resistance, we caution that beneficial species interactions may shift under extreme droughts. Thus, there is an urgent need to investigate species interaction effects on resilience in more depth to adapt forest trees to increasing drought stress.
A Multidimensional Pairwise Comparison Model for Heterogeneous Perceptions with an Application to Modelling the Perceived Truthfulness of Public Statements on COVID-19
Authors: Yu Qiushi , Quinn Kevin M. 
Published: March 2022

AbstractPairwise comparison models are an important type of latent attribute measurement model with broad applications in the social and behavioural sciences. Current pairwise comparison models are typically unidimensional. The existing multidimensional pairwise comparison models tend to be difficult to interpret and they are unable to identify groups of raters that share the same rater-specific parameters. To fill this gap, we propose a new multidimensional pairwise comparison model with enhanced interpretability which explicitly models how object attributes on different dimensions are differentially perceived by raters. Moreover, we add a Dirichlet process prior on rater-specific parameters which allows us to flexibly cluster raters into groups with similar perceptual orientations. We conduct simulation studies to show that the new model is able to recover the true latent variable values from the observed binary choice data. We use the new model to analyse original survey data regarding the perceived truthfulness of statements on COVID-19 collected in the summer of 2020. By leveraging the strengths of the new model, we find that the partisanship of the speaker and the partisanship of the respondent account for the majority of the variation in perceived truthfulness, with statements made by co-partisans being viewed as more truthful.
Cluster of humanPuumala orthohantavirusinfections due to indoor exposure?—An interdisciplinary outbreak investigation
Authors: Princk Christina , Drewes Stephan , Meyer‐Schlinkmann Kristin M. , Saathoff Marion , Binder Florian , Freise Jona , Tenner Beate , Weiss Sabrina , Hofmann Jörg , Esser Jutta , Runge Martin , Jacob Jens , Ulrich Rainer G. , Dreesman Johannes 
Published: March 2022

AbstractPuumala orthohantavirus(PUUV) is the most important hantavirus species in Europe, causing the majority of human hantavirus disease cases. In central and western Europe, the occurrence of human infections is mainly driven by bank vole population dynamics influenced by beech mast. In Germany, hantavirus epidemic years are observed in 2‐ to 5‐year intervals. Many of the human infections are recorded in summer and early autumn, coinciding with peaks in bank vole populations. Here, we describe a molecular epidemiological investigation in a small company with eight employees of whom five contracted hantavirus infections in late 2017. Standardized interviews with employees were conducted to assess the circumstances under which the disease cluster occurred, how the employees were exposed and which counteractive measures were taken. Initially, two employees were admitted to hospital and serologically diagnosed with hantavirus infection. Subsequently, further investigations were conducted. By means of a self‐administered questionnaire, three additional symptomatic cases could be identified. The hospital patients' sera were investigated and revealed in one patient a partial PUUV L segment sequence, which was identical to PUUV sequences from several bank voles collected in close proximity to company buildings. This investigation highlights the importance of a One Health approach that combines efforts from human and veterinary medicine, ecology and public health to reveal the origin of hantavirus disease clusters.
Improved Physiological Markers of Omega-3 Status and Compliance With Omega-3 Supplementation in Division I Track and Field and Cross-Country Athletes: A Randomized Controlled Crossover Trial
Authors: Graybeal Austin J. , Helms Brooke , Couris Katie , Thomas Daphne , Johnston Tatum , Dahan Victoria , Escobedo Nina , Willis Jada L. 
Published: March 2022

A sufficient omega-3 index may enhance cardiovascular function, enhance performance, and decrease inflammation. However, most collegiate athletes are deficient in omega-3s, requiring supplementation. A new type of omega-3 (N3) supplement, Enhanced Recovery™ (ER), claims to improve N3 index while addressing the current issues with traditional supplementation. The purpose of this study was to determine if ER improves N3 status and enhances compliance compared with the current standard in collegiate Division I Track and Field and cross-country athletes during a competitive season. Twenty-five (male = 15 and female = 10) athletes completed this longitudinal, randomized controlled crossover trial. Measurements of N3 status were collected at baseline prior to supplementation, and every 2 weeks for 6 weeks with a 33- to 36-day washout period before crossing over. Supplement compliance and dietary intake of N3 rich foods were collected throughout. Visual analog scales and an exit survey asked questions regarding each treatment. Results showed that N3 index increases within 6 weeks (p < .001) for ER (+37.5%) and control (CON; +55.1%), with small differences between treatments at Weeks 4 (ER = 7.3 ± 1.0; CON = 7.7 ± 1.1; p = .043) and 6 (ER = 7.4 ± 1.2; CON = 7.9 ± 1.2; p = .043). Dietary intake of N3-rich foods and supplement compliance were significant drivers of improvements in N3 status (p < .050). Compliance was not different between treatments but was affected by sex (males = 90.0 ± 17.0% and females = 76.5 ± 21.0%; p = .040), likability (p = .001; r = .77, p < .001), ease (p = .023; r = .53, p = .006), and supplement preference (p = .004), which appeared to favor ER. We conclude that consumption of N3-rich foods and consistent supplementation should be implemented for improvements in N3 status in collegiate athletes, but taste tests/trial periods with ER or CON may help determine preference and improve compliance.
Population Pharmacokinetic-Pharmacodynamic Target Attainment Analysis of Flomoxef in the Serum and Liver Tissue of Patients Undergoing Hepatic Resection
Authors: Komatsu Toshiaki , Tsumuraya Satomi , Takayama Yoko , Kaizu Takashi , Okamoto Mikiko , Tajima Hiroshi , Nishizawa Nobuyuki , Kubo Hidefumi , Kumamoto Yusuke , Okamoto Hirotsugu , Hanaki Hideaki , Atsuda Koichiro 
Published: March 2022

The purpose of this study was to investigate the population pharmacokinetics of prophylactic flomoxef based on serum and liver tissue concentrations and to demonstrate a pharmacodynamic target concentration in the serum and liver tissue exceeding the MIC in order to design an effective dosing regimen. Serum samples (
n
= 210) and liver tissue samples (
n
= 29) from 43 individuals were analyzed using a nonlinear mixed-effects model. The pharmacodynamics index target value was regarded as the probability of maintaining flomoxef serum trough and liver tissue concentrations exceeding the MIC
90
values, 0.5 mg/L and 1.0 mg/L, for
Escherichia coli
and methicillin-susceptible
Staphylococcus aureus
, respectively. The final population pharmacokinetic model was a two-compartment model with linear elimination.
Telemetric non-contact intraocular pressure monitoring with an implanted sensor in patients with glaucoma: long-term safety report and monitoring data
Authors: Schmidt Ilka , Plange Niklas , Walter Peter , Koutsonas Antonis 
Published: March 2022

Background/aimsGlaucoma is a chronic disease that requires lifelong monitoring and treatment. However, its control is limited due to discontinuous intraocular pressure (IOP) monitoring related to the practitioners’ office hours. Implantable telemetric IOP sensors have made self-measurements possible and provide important information regarding the IOP profiles of patients. However, limited long-term monitoring data are currently available.MethodsIn the ARGOS-01 study, a telemetric IOP sensor was implanted in the ciliary sulcus of six patients with open-angle glaucoma during cataract surgery between 2011 and 2012. This study reports telemetric monitoring data collected by self-tonometry and automated measurements and during outpatient visits, including an analysis of one active patient with several years of follow-up. The long-term safety, tolerability and functionality were assessed in the remaining patients during the last visit.ResultsThe follow-up period was up to 10 years, in which almost 25 000 IOP measurements were performed. The patients had excellent tolerance of the implanted sensor and did not experience sensor-related discomfort or complications. The active patient reported easy handling of self-tonometry and did not experience long-term restrictions in activities of daily living due to the implanted sensor. Telemetric data provide an insight into patients’ measurement routines and IOP fluctuations.ConclusionSo far, our data suggest good long-term safety, tolerability and functionality of the implanted sensors up to almost ten years. Such sensors may help facilitate patients’ self-measurements of IOP. This disease monitoring method should be investigated further to determine if it helps improve wider patient experience, engagement and visual prognosis for those being treated for complex glaucoma.
Significance of tibial MRI findings of special forces recruits at the onset of their training
Authors: Milgrom Charles , Tsur N , Eshed I , Milgrom Y , Beyth S , Spitzer E , Gofman I , Finestone A S 
Published: March 2022

IntroductionMRI is commonly used to evaluate medial tibial stress syndrome (MTSS), based on grading assessments developed in civilian populations. When MTSS represents stress fracture, rest is required to allow for bone remodelling to occur. False positive evaluations can lead to unnecessary recruit attrition.MethodsThirty randomly selected new recruits to a special forces training unit underwent MRI of their tibias using the T2-Dixon sequence at the onset of training. Evaluation was according to the Fredericson MTSS grading system. Prior to undergoing MRI, anthropomorphic measurements, a survey of sports history and an orthopaedic examination of subject tibias were performed. Orthopaedic follow-up was through 11 weeks of training.ResultsMedial periosteal oedema without the presence of bone marrow oedema, corresponding to a grade 1 stress reaction, was present on MRI in 10 recruits (17 tibias). In only one case did the periosteal oedema include the posterior aspect of the medial cortex where medial tibial stress fractures usually occur. Tibial tenderness was present in seven tibias on examination done just prior to the MRI studies, but none were symptomatic and only one had periosteal oedema present on MRI, but without anatomical correlation between the site of the tenderness and the periosteal oedema. During subsequent training, five tibias in four recruits developed pain and tenderness. Two had periosteal oedema in their prior MRIs, but the location did not coincide anatomically with that of the tibial tenderness. The time from stopping sports before induction and the presence of periosteal oedema was not significant.ConclusionPeriosteal oedema, one of the hallmarks used in MRI grading systems to evaluate MTSS, was found to have a 37.7% false positive rate for anatomically corresponding tibial tenderness at the time of the examination and during subsequent training, indicating the grading systems’ low utility for the military.