bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying Information Gaps in Electronic Health Records by Using Natural Language Processing: Gynecologic Surgery History Identification
Authors: Moon Sungrim , Carlson Luke A , Moser Ethan D , Agnikula Kshatriya Bhavani Singh , Smith Carin Y , Rocca Walter A , Gazzuola Rocca Liliana , Bielinski Suzette J , Liu Hongfang , Larson Nicholas B 
Published: January 2022

Background
Electronic health records (EHRs) are a rich source of longitudinal patient data. However, missing information due to clinical care that predated the implementation of EHR system(s) or care that occurred at different medical institutions impedes complete ascertainment of a patient’s medical history.

Objective
This study aimed to investigate information discrepancies and to quantify information gaps by comparing the gynecological surgical history extracted from an EHR of a single institution by using natural language processing (NLP) techniques with the manually curated surgical history information through chart review of records from multiple independent regional health care institutions.

Methods
To facilitate high-throughput evaluation, we developed a rule-based NLP algorithm to detect gynecological surgery history from the unstructured narrative of the Mayo Clinic EHR. These results were compared to a gold standard cohort of 3870 women with gynecological surgery status adjudicated using the Rochester Epidemiology Project medical records–linkage system. We quantified and characterized the information gaps observed that led to misclassification of the surgical status.

Results
The NLP algorithm achieved precision of 0.85, recall of 0.82, and F1-score of 0.83 in the test set (n=265) relative to outcomes abstracted from the Mayo EHR. This performance attenuated when directly compared to the gold standard (precision 0.79, recall 0.76, and F1-score 0.76), with the majority of misclassifications being false negatives in nature. We then applied the algorithm to the remaining patients (n=3340) and identified 2 types of information gaps through error analysis. First, 6% (199/3340) of women in this study had no recorded surgery information or partial information in the EHR. Second, 4.3% (144/3340) of women had inconsistent or inaccurate information within the clinical narrative owing to misinterpreted information, erroneous “copy and paste,” or incorrect information provided by patients. Additionally, the NLP algorithm misclassified the surgery status of 3.6% (121/3340) of women.

Conclusions
Although NLP techniques were able to adequately recreate the gynecologic surgical status from the clinical narrative, missing or inaccurately reported and recorded information resulted in much of the misclassification observed. Therefore, alternative approaches to collect or curate surgical history are needed.
An Accessible Communication System for Population-Based Genetic Testing: Development and Usability Study
Authors: Coffin Tara , Bowen Deborah , Swisher Elizabeth , Lu Karen , Rayes Nadine , Norquist Barbara , Blank Stephanie , Levine Douglas , Bakkum-Gamez Jamie , Fleming Gini , Olopade Olufunmilayo , D’Andrea Alan , Nebgen Denise , Peterson Christine , Munsell Mark , Gavin Kathleen , Lechner Rebecca , Crase Jamie , Polinsky Deborah , Romero Iris 
Published: January 2022

BackgroundGenetic testing uptake is low, despite the well-established connection between pathogenic variants in certain cancer-linked susceptibility genes and ovarian cancer risk. Given that most major insurers cover genetic testing for those with a family history suggestive of hereditary cancer, the issue may lie in access to genetic testing. Remotely accessible web-based communication systems may improve awareness, and uptake, of genetic testing services.ObjectiveThis study aims to present the development and formative evaluation of the multistep web-based communication system required to support the implementation of, and access to, genetic testing.MethodsWhile designing the multistep web-based communication system, we considered various barriers and facilitators to genetic testing, guided by dimensions of accessibility. In addition to conducting usability testing, we performed ongoing assessments focusing on the function of the web-based system and participant response rates, with the goal of continuing to make modifications to the web-based communication system as it is in use.ResultsThe combined approach of usability testing and expert user experience consultation resulted in several modifications to the multistep web-based communication system, including changes that related to imagery and content, web accessibility, and general organization of the web-based system. All recommendations were made with the goal of improving the overall accessibility of the web-based communication system.ConclusionsA multistep web-based communication system appears to be an effective way to address many potential barriers to access, which may otherwise make genetic testing difficult for at-risk individuals to participate in. Importantly, some dimensions of access were easy to assess before study recruitment, but other aspects of the communication system required ongoing assessment during the implementation process of the Making Genetic Testing Accessible study.
Instalaciones franciscanas en el puerto de Valparaíso en los siglo XVII - siglo XX
Authors: Jiménez Vergara Cecilia 
Published: January 2022

Esta investigación permitió reconstruir la historia de las instalaciones franciscanas aledañas a la iglesia La Matriz, entre el siglo XVII hasta su demolición a mediados del siglo XX, basada en registros historiográficos documentales, de diversas órdenes religiosas, relacionadas con la iglesia, convento, y colegios que albergaron.
Asimismo, junto con reconstituir gráficamente las planimetrías, descubrir la estrecha relación del conjunto franciscano con el espacio urbano que lo antecedía denominado Plazuela San Francisco donde se realizaban actividades “sacras “ y “profanas” tales como procesiones, misas, obras de teatro, peleas de gallo y corridas de toros. La Plazuela persistió como espacio público aún después de la demolición de la Iglesia y convento hasta las últimas décadas del siglo XX. cuando fue transferida en comodato a la P.D.I.
La investigación determinó que este espacio urbano posee huellas que forman parte de la memoria colectiva y constituye un patrimonio olvidado necesario de recuperar no sólo para los vecinos y la ciudad, sino también factible de incorporar al Área Histórica de Valparaíso reconocida por la UNESCO como Patrimonio Mundial.
Pengaruh kurs, inflasi, PDB dan harga karet internasional terhadap ekspor karet Indonesia Ke Tiongkok dan Amerika Serikat
Authors: Fihri Faisal , Haryadi Haryadi , Nurhayani Nurhayani 
Published: January 2022

This study aims to: 1) calculate and analyze the development of exchange rates, inflation, GDP, international rubber prices, and Indonesian rubber exports to China and the United States. 2) To determine the income contribution of women workers in Talang Village, 3). To calculate and analyze the factors that affect the export of Indonesian rubber to China and the United States. The analytical method used is descriptive quantitative using multiple linear regression analysis. The results show that the exchange rate development fluctuated from 2001 to 2019, with an average exchange rate development from 2001 to 2019 of 3.13 percent. Then the average general annual inflation of Indonesia for 19 years with inflation developments that occur up and down or fluctuate. The average growth of rubber prices is 9.24 percent. Furthermore, the volume of rubber exports to China in 2001-2019 tends to decrease. The average development of rubber export volume to China in 2001-2019 was -1.95 percent. Meanwhile, the development of rubber export volume to America in 2001-2019 tends to increase. The average growth of rubber export volume to China in 2001-2019 was 1.34 percent. Based on the results of multiple linear regression, the importance of rubber exports to China is influenced by the variables of the exchange rate, GDP, and rubber prices. Meanwhile, the rubber price variable only affects the volume of rubber exports to America.
Keywords: Export of rubber, Exchange rate, Inflation, GDP, Rubber price
Mediación pedagógica de lecturas en inglés para estudiantes con un nivel básico del idioma en la cátedra de Educación Preescolar UNED, Costa Rica
Authors: Solís Solís Delia María , Acevedo Nevermann Katherine 
Published: January 2022

La necesidad de desarrollar competencias lingüísticas en un segundo idioma en la primera infancia costarricense ha generado que las Universidades estatales empiecen a revisar sus programas de estudio para la formación de formadores. Esta realidad y la mediación de materiales en inglés como requisito de acreditación propiciaron la necesidad de incorporar lecturas en un segundo idioma en las diferentes asignaturas de la Carrera de Educación Prescolar de la UNED, a sabiendas de que la población carece del dominio de este. La intención de este estudio fue mediar lecturas en inglés con la estrategia basadas en tareas y trabajo cooperativo en estudiantes de diplomado con un dominio básico del idioma. Ambas estrategias se escogieron por ser apropiadas para el trabajo a distancia. El material elegido por expertos fue una lectura y un video, los cuales cumplen los siguientes requisitos: 1- la lectura: corta (no más de 5 páginas), vocabulario simple e imágenes ilustrativas. 2-el video: cortos (no más de 4 minutos) y con subtítulos en inglés. La mediación y evaluación del material se realizó en la plataforma, a través de actividades de predicción. Las actividades evaluaron la habilidad de comprensión, escucha y se presentaron en un foro académico. Se encontró que mientras la población estudiantil pueda utilizar todos los recursos visuales, auditivos y conocimientos previos en las actividades de evaluación, el idioma como tal no representa un obstáculo. Estos resultados sugieren el beneficio de la estrategia del trabajo en tareas, el trabajo colaborativo y las actividades de predicción como técnicas para mediar el material en otro idioma.
Peranan Lingkungan Sosial Terhadap Pembentukan Sikap Peduli Lingkungan Peserta Didik Di MAS Al-Islam Petala Bumi
Authors: Muslim Muslim , Almegi Almegi , Alfiah Alfiah , Akmal Akmal , Amelia Hutri Rizki 
Published: January 2022

Peranan lingkungan sosial memiliki peranan penting terhadap pembentukan sikap peduli lingkungan peserta didik. Adapun lingkungan sosial yaitu lingkungan keluarga, madrasah masyarakat. Penelitian ini bertujuan untuk mengetahui peranan lingkungan keluarga, madrasah , dan masyarakat terhadap pembentukan sikap peduli lingkungan peserta didik di MAS AL ISLAM Penelitian ini menggunakan metode penelitian survey. Sampel penelitian berjumlah 100 peserta didik. Instrumen dalam penelitian ini berupa kuesioner, studi literatur, dan studi dokumentasi. Analisis data menggunakan analisis regresi linear ganda. Hasil penelitian menunjukan bahwa lingkungan keluarga, madrasah, dan masyarakat memberikan peranan yang berarti dan lingkungan masyarakat yang berperan paling tinggi terhadap pembentukan sikap peduli lingkungan peserta didik
Information and logical model of digitalization of education process in universities
Authors: Medyankina Elena Lvovna 
Published: January 2022

The article describes the teaching model in terms of digitalization of universities. Digitalization of universities in this case means the work of university personnel with automated digital algorithms in order to successfully solve modern educational problems. The principles that create such a model are indicated, the goals facing the teacher are formulated depending on the level of knowledge transmitted to students, as well as the conditions for the effectiveness of training, depending on the degree of individualization of the approach. The data at the initial level of student learning and, accordingly, the required level of acquired knowledge have been found important. When compiling the model, it was taken into account that a small level of individualization is inherent in activities in the form of demonstration and modeling, therefore, it implies the student's independent control of the objects and processes being demonstrated, in particular, change of their parameters, establishing different degrees of detail, and forming spatial-temporal modes. The scenario of interaction between the teacher and the student includes the following actions: transfer of control; assessment of the student's condition according to the given parameters and comparison of the given educational situation with the set of provided answers; analysis of the answers, requests or reactions of the student; providing assignments or messages; collection of educational information; creation and delivery of system comments. The result of the work is the author's model itself, which includes a scenario of interaction between a teacher and
a student; a scheme for identifying the uniformity of signs and organization of teaching in the digitalization of universities; the components of the model of the object of study; automation of task development; the algorithm of the model infrastructure, consisting of the blocks Training, Final Control, Instructing, and a block of methodological consulting. This model will contribute to solving problems in the educational system that arise in connection with the factors leading to forced long interruptions in full-time education.
Hepatic copper accumulates in ferrets with and without hepatobiliary disease
Authors: Richard Julianne N. , Graham Jennifer E. , Center Sharon A. , Garner Michael M. , Reavill Drury R. 
Published: January 2022

Abstract

OBJECTIVE
To determine hepatic copper concentrations and zonal distribution in ferrets with and without hepatobiliary disease, validate rhodanine-based qualitative copper scoring and digital copper quantification in ferret hepatic samples, and ascertain whether clinical features predicted copper accumulation.

ANIMALS
34 ferrets, including 7 with necroinflammatory disease, 5 with hepatocellular carcinoma, 13 with non-necroinflammatory disease, and 9 with no hepatobiliary disease.

PROCEDURES
Rhodanine-based digital copper quantification was validated by use of liver dually measured by atomic absorption spectroscopy and digital scanning (R2 = 0.98). Clinical features and hepatic copper scores and concentrations (dry weight liver) were compared between groups. Zonal copper distribution was determined.

RESULTS
Hepatic copper concentration was strongly correlated with copper scores (ρ = 0.88). Ferrets with hepatobiliary disease were significantly older and had significantly higher serum alkaline phosphatase and γ-glutamyltransferase activities and creatinine concentrations. Centrilobular copper accumulated in 23 of 34 (64%) ferrets with (n = 15) and without (8) hepatobiliary disease. Median copper concentrations were not significantly different between ferrets with and without hepatobiliary disease but were significantly higher within neoplastic hepatic tissue in ferrets with hepatocellular carcinoma. Hepatic copper concentrations exceeded feline (> 180 µg/g) and canine (> 400 µg/g) reference limits in 19 and 9 ferrets, respectively. Hepatic copper > 1,000 µg/g occurred in 5 ferrets with and 2 without hepatobiliary disease. Clinical features did not predict copper accumulation.

CLINICAL RELEVANCE
Rhodanine-based digital copper quantification and qualitative copper scoring discerned liver copper accumulation in ferrets. Ferrets with and without hepatobiliary disease displayed a propensity for centrilobular hepatic copper accumulation of uncertain clinical importance. Clinical and clinicopathologic features could not exclusively implicate pathologic copper accumulation.
Associations between differing magnitudes of inter-limb asymmetry and linear and change of direction speed performance in male youth soccer players
Authors: Işın Ali , Akdağ Eren , Özdoğan Emel Çetin , Bishop Chris 
Published: January 2022

Abstract

Study aim: This study examines the relationship between different magnitudes of asymmetry and their effects on speed performance.

Material and methods: Forty-two sub-elite male youth soccer players performed a 30-m sprint, change of direction, single leg countermovement jump and single leg hop. Subjects were divided into groups with vertical and horizontal asymmetry, and both groups were then divided into three groups according to magnitudes of inter-limb asymmetry (<5%, 5–10%, and >10%).

Results: The results showed no significant correlation between different jump asymmetry magnitudes and the mentioned outcomes of speed performance (p > 0.05). In addition, larger asymmetries resulted in faster linear speed, even if small differences (g range = 0.00 to 0.57; p > 0.05). But this was not similar for change of direction speed (g range = –0.42 to 0.34; p > 0.05).

Conclusions: There are inconsistent findings for the effects of inter-limb asymmetries on speed performance. The results of the present study indicate that the magnitude of asymmetry had no meaningful association with independent measures of performance in soccer players. Therefore, it seems more likely to explain the effects of individual asymmetries on performance rather than the idea that asymmetry negatively affects performance.
Climate change impact on the quality of freshwater resources and waste management in the context of 2030 Agenda on Sustainable Development
Authors: Mic-Soare Cristiana , Mic Stelian-Mihai 
Published: January 2022

Abstract
The importance of the effects of climate change has been emphasized on a variety of levels and from a number of different perspectives: on a country, regional or international level; affecting agriculture, energy, tourism, shipping, economic activities, various ecosystems as well as human health. It has been repeatedly recognized that climate change has a significant impact on freshwaters, including on their quality, availability and sustainability. From a different perspective, that of the circular economy, management strategies applied in respect to freshwaters have a direct impact on the climate. At the same time, improper waste management has a very high negative contribution to the latest climate changes, on one hand, and on the quality and availability of freshwater resources, on the other hand. Nevertheless, how all the three different above-mentioned elements – climate change, freshwater resources and waste management – are linked in the context of 2030 Agenda on sustainable development is yet to be thoroughly discussed in the scientific literature in the field of environmental law. Thus, by analysing a sample of the legal doctrine contributions published starting from 2016, as well as several official documents issued by the United Nations, we aimed to establish if all the three above-mentioned elements are interlinked and how they impact each other. As a result, we determined that there is a clear necessity for states to take unified measures to address climate change, protection and management of the freshwater resources and consistent waste management in the context of the Sustainable development goals (SDGs) introduced by the 2030 Agenda.
Approaching sustainable development practices and quality strategies in the Romanian dairy industry
Authors: Neacşu Nicoleta Andreea , Madar Anca 
Published: January 2022

Abstract
The Romanian dairy industry has experienced a significant evolution in the last 30 years. Improving product quality is a decisive and important factor for increasing competitiveness in both domestic and foreign markets. The concept of sustainability is increasingly found in the quality policies and objectives set by dairy producers. This paper aims to capture the current sustainable development practices and quality strategies applied by companies in the dairy sector in Romania and how they are perceived by consumers. In order to highlight the opinions and attitudes of Romanians regarding the quality strategies and sustainable development practices that are applied in the dairy sector, the authors conducted a quantitative marketing research among the Romanian population. The sampling method was non-random, and a questionnaire was used to collect the data, which was displayed on a web page (Computer Assisted Web Interviewing). The research revealed that many Romanians have heard of the concept of “sustainable development”, but do not know very well what it refers to. The authors consider that the topic is up to date and that based on the results of this research, companies in the analyzed sector can improve their applied quality strategies and adopt new sustainable development practices in order to improve their products and increase consumer satisfaction.
IFRS implementation in Romania Certified Accountants perspective
Authors: Stoica Dragos Andrei , Rogoz Marius Eugen 
Published: January 2022

Abstract
This study aims to investigate the opinions of certified accountants in Romania on the implementation of the IAS/IFRS (International Accounting Standards/International Financial Reporting Standards) in an emergent country that has a short to medium experience in adopting and implementing the standards.
Considerations on penalty clauses: regulation and enforceability
Authors: Chirieac Roxana Maria 
Published: January 2022

Abstract
Penalty clauses are regulated in the Romanian law through the provisions of the civil Code. These types of clauses are frequently inserted in commercial contracts in order to ensure that all contracting parties will respect their obligations, or will pay the pre-evaluated damages considered by the parties at the conclusion of the contract. As opposed to the common-law regulations, the continental law systems allow and support such clauses, mainly because of the liberty of the parties when concluding a contract; nevertheless, our legislation, as other European legislations allow the mutability of penalty clauses, when they are deemed excessive.
In the present study, we aimed to analyze the nature of the penalty clause in the Romanian regulations, as well as study their applicability in commercial contracts, especially when inserted in contracts that are concluded over longer periods of time for the supply of services. We aim to understand if such a clause might be deemed inapplicable if one of the parties decides upon the termination of the contract ahead of term or simply wants to reduce the clause in order to pay a lesser penalty.
The legislation states that such clauses may be amended by the court when part of the principal obligation was partly upheld by the party and its execution has profited the creditor, or when the penalty is “manifestly excessive” as opposed to the prejudice that could have been foreseen by the parties at the conclusion of the contract. Based on the current state of legislation, while analyzing doctrine and jurisprudence, we aim to underline what a manifestly excessive penalty should be.