bluuebunny/crossref_metadata_2025_split huggingface dataset:
ALMA High-frequency Long-baseline Campaign in 2017: An Investigation of Phase-referencing Cycle Times and Effective Baseline Lengths Using Band-to-band and In-band Phase Calibration Techniques
Authors: Maud Luke T. , Asaki Yoshiharu , Dent William R. F. , Hirota Akihiko , Fomalont Edward B. , Takahashi Satoko , Matsushita Satoki , Phillips Neil M. , Sawada Tsuyoshi , Corder Stuartt , Carpenter John 
Published: February 2022

Abstract
The Atacama Large Millimeter/submillimeter Array can achieve unprecedented spatial resolutions of 15 to 5 mas with the longest baselines of 16 km and observing at the highest frequencies of 275–950 GHz (1.09–0.30 mm). Two conditions are paramount for successful observations at these frequencies: a phase calibrator in close proximity to the science target and a stable-enough atmosphere to provide a low residual phase rms post-phase-referencing. We investigate the effect of phase-referencing cycle times, for in-band and band-to-band (B2B) observing techniques, using close and distant phase calibrators, at bands 7, 8, and 9 for baselines >2000 m. We find that (1) the phase rms estimated from baselines longer than the effective baseline increases as a function of

time

. (2) The expected coherence estimated using the expected phase rms corresponds well to the achieved image coherence. (3) Faster phase-referencing cycle times (<1 minute) improve phase calibration accuracy and image coherence when close phase calibrators (<2°) are used. (4) For cycle times <2 minutes the negative impact of distant phase calibrators dominates the phase error budget. We also explore whether a theoretical parameterization of the effective baseline used to estimate the phase rms and a phase stability measurement, combined with an empirical parameterization of coherence degradation as a function of calibrator separation, is suitable in estimating the expected coherence of target images. The latter proves to be more accurate. Finally, we illustrate a pragmatic approach in establishing an optimal observing strategy via dynamic cycle times and on-calibrator scan lengths.
Optical Confirmation of X-Ray-selected Galaxy Clusters from the Swift AGN and Cluster Survey with MDM and Pan-STARRS Data. III
Authors: Bhatiani Saloni , Dai Xinyu , Griffin Rhiannon D. , Nugent Jenna M. , Kochanek Christopher S. , Bregman Joel N. 
Published: February 2022

Abstract
To understand structure formation in the universe and impose stronger constraints on the cluster mass function and cosmological models, it is important to have large galaxy cluster catalogs. The Swift AGN and Cluster Survey is a serendipitous X-ray survey aimed at building a large statistically selected X-ray cluster catalog with 442 cluster candidates in its first release. Our initial SDSS follow-up study confirmed 50% of clusters in the Sloan Digital Sky Survey footprint as z < 0.5 clusters. Here we present further optical follow-up analysis of 248 (out of 442) cluster candidates from the Swift cluster catalog using multiband imaging from the MDM 2.4 m telescope and the Pan-STARRS survey. We report the optical confirmation of 55 clusters with >3σ galaxy overdensities and detectable red sequences in the color–magnitude space. The majority of these confirmed clusters have redshifts z < 0.6. The remaining candidates are potentially higher-redshift clusters that are excellent targets for infrared observations. We report the X-ray luminosity and the optical richness for these confirmed clusters. We also discuss the distinction between X-ray and optical observables for the detected and nondetected cluster candidates.
Cellular Adhesion Is a Controlling Factor in Neutrophil Extracellular Trap Formation Induced by Anti-Neutrophil Cytoplasmic Antibodies
Authors: Lelliott Patrick M , Nishide Masayuki , Pavillon Nicolas , Okita Yasutaka , Shibahara Takayuki , Mizuno Yumiko , Yoshimura Hanako , Obata Sho , Kumanogoh Atsushi , Smith Nicholas I 
Published: February 2022

Abstract
Anti-neutrophil cytoplasmic Ab (ANCA)–associated vasculitis (AAV) is a life-threatening condition characterized by improper activation of neutrophils and the release of neutrophil extracellular traps (NETs) in small vessels. This study aimed to explain the role of NETs in AAV pathogenesis by investigating a link between adhesion and NET release using human neutrophils. We leveraged an imaging flow cytometry–based assay and three-dimensional culture to demonstrate that neutrophil adhesion is essential for ANCA-induced NET formation. We confirmed this requirement for cell adhesion using standard microscopy on ultra-low attachment hydrogel surfaces and demonstrate that this depends on the focal adhesion kinase pathway as determined using inhibitors for multiple targets in this process. ANCA increased expression of β2 integrins on neutrophils, and we confirmed that these integrins were required for NET formation using blocking Abs. Finally, inhibitors for oxidative burst prevented NET formation, and this oxidative burst was mediated by the focal adhesion pathway. Overall, our findings reveal a central role for neutrophil attachment in NET formation in response to ANCAs, helping to explain the restricted localization pattern of vessel damage, and suggesting that targeting neutrophil adhesion factors may be beneficial in preventing pathological damage from NETs during AAV.
Direct Binding of Rap1 to Talin1 and to MRL Proteins Promotes Integrin Activation in CD4+ T Cells
Authors: Lagarrigue Frederic , Tan Boyang , Du Qinyi , Fan Zhichao , Lopez-Ramirez Miguel A , Gingras Alexandre R , Wang Hsin , Qi Weiwei , Sun Hao 
Published: February 2022

Abstract
Agonist-induced Rap1 GTP loading results in integrin activation involved in T cell trafficking and functions. MRL proteins Rap1-interacting adapter molecule (RIAM) and lamellipodin (LPD) are Rap1 effectors that can recruit talin1 to integrins, resulting in integrin activation. Recent work also implicates direct Rap1–talin1 interaction in integrin activation. Here, we analyze in mice the connections between Rap1 and talin1 that support integrin activation in conventional CD4+ T (Tconv) and CD25HiFoxp3+CD4+ regulatory T (Treg) cells. Talin1(R35E, R118E) mutation that disrupts both Rap1 binding sites results in a partial defect in αLβ2, α4β1, and α4β7 integrin activation in both Tconv and Treg cells with resulting defects in T cell homing. Talin1(R35E,R118E) Tconv manifested reduced capacity to induce colitis in an adoptive transfer mouse model. Loss of RIAM exacerbates the defects in Treg cell function caused by the talin1(R35E,R118E) mutation, and deleting both MRL proteins in combination with talin1(R35E,R118E) phenocopy the complete lack of integrin activation observed in Rap1a/b-null Treg cells. In sum, these data reveal the functionally significant connections between Rap1 and talin1 that enable αLβ2, α4β1, and α4β7 integrin activation in CD4+ T cells.
A NEW HYBRID ALGORITHM MPCM FOR SINGLE OBJECTIVE OPTIMIZATION PROBLEMS
Authors: NGUYEN TRONG TIEN  
Published: February 2022

One of the biggest challenges for researchers is finding optimal solutions or nearly optimal solutions for single-objective problems.
In this article, authors have proposed new algorithm called MPCM for resolving single-objective problems. This algorithm is combined of four algorithms: Mean-Search, PSOUpdate, CRO operator and new operator call Min-Max. The authors use some parameters to balance between the local search and global search. The results demonstrate that, with the participation of Min-Max Operator, MPCM gives the good results on 23 benchmark functions. The results of MPCM will compare with three famous algorithms such as Particle Swarm Optimization (PSO), Real Code Chemical Reaction Optimization (RCCRO) and Mean PSO-CRO (MPC) for demonstration the efficiency.
A NEW MULTI-MOTOR DRIVE SYSTEM BASED ON FOUR-SWITCH THREE-PHASE INVERTER TOPOLOGIES
Authors: PHAM CONG DUY  
Published: February 2022

Vietnam encourages greenhouse technology applications for high-tech agricultural production. The microclimate of greenhouses is the key factor for better plant growth. The greenhouse microclimate can be improved by control actions, such as heating, ventilation, and carbon dioxide enrichment to provide appropriate environmental conditions for crops. The multi-motor drive systems using six-switch three-phase inverter topologies are applied for greenhouse fans. In order to decrease to size and cost of effectiveness drive systems, the paper proposes a new multi-motor drive system based on four-switch three-phase inverter topologies which are applied to two-level hysteresis current controllers. The proposed solution has been tested to a four-permanent-magnet synchronous motor (PMSM) drive system. The simulation results are carried out to show the effectiveness of the proposed solution.
Sistema de interacción (low-tech) para pieza de arte Move-on
Authors: Pedrero Agustín Linares 
Published: February 2022

Este artículo trata de exponer un sistema alternativo (y algo rudimenta-rio) para establecer una comunicación con el ordenador, en la que participan sen-sores muy simples, los cuales mandan una señal que es interpretada por el orde-nador (como pulsación de tecla) para activar un comportamiento multimedia. Con-templando la eficacia que requiere para su funcionamiento, a tal propósito se ex-pone una instalación artística de carácter interactivo, Move-on, en cuyos procesos se necesita disparar el uso de animación fotográfica y el encendido de unos focos. La instalación establece una comunicación con el espectador a través del cuer-po, más concretamente, del movimiento de su propio cuerpo.
Pengelompokkan Tingkat Pemahaman Guru PAUD Terhadap Pembelajaran Berbasis STEAM Menggunakan Metode X-Means Clustering
Authors: Fatimah Siti , Suriati Suriati , Usman Ari 
Published: February 2022

In the era of the industrial revolution 4.0, quantity is not a measure of achieving early childhood outcomes, but how teachers create quality resource based inventions. To form creative and adaptive resources for technology, the teacher must changes the facilities, infrastructure and learning reconstruction. Learning that is prepared to welcome children to face the 21st century is learning based on Science, Technology, Engineering, Art, and Mathematics (STEAM). STEAM is used to consider the interconnected essence of science, technology, engineering, arts and mathematics disciplines and their significance in the long-term academic performance of children. Responding to STEAM-based learning that PAUD teachers need to incorporate in cultivating the creativity of children, it is important to know the degree to which PAUD teachers understand STEAM-based learning. This research discusses the use of the X-Means clustering algorithm as one of the data mining algorithms in grouping data on the level of comprehensions of PAUD teachers on STEAM-based learning. This research discusses the use of the X-Means Clustering algorithm as one of the data mining algorithms in grouping data on the level of comprehensions of PAUD teachers on STEAM-based learning.
Post-UNESCO Effect
Authors: Chakraborty Ayantika 
Published: February 2022

Chhau, a traditional masked dance form of West Bengal has been enlisted as ‘UNESCO- Intangible Cultural Heritage of Humanity, 2010’. In 2015, UNESCO along with the MSME of Government of West Bengal developed a ‘Rural Craft Hub’ in Chorida village of Purulia district centring Chhau. Consequently, tourism in the area got international and national patronage. This entire phenomenon encouraged the commercialization of the traditional dance and craft form associated with Chhau as a result of heritagization. Unfortunately, the implication of the heritagization happened in a flawed fashion which eventually led to folklorization and institutionalization while compromising their contextual significance. The paper explores how heritagization ensures the sustainability of intangible tradition like Chhau while leading to folklorization and institutionalization of performance and craft. The paper also documents the history and ritualistic significance of Chhau to draw a lucid comparison between the traditional form and the form which is the result of folklorization. The paper establishes that the Heritagization- Folklorization- Institutionalisation are intertwined with each other in the context of Chhau. From the interviews of the tourists and locals associated with Chhau, it is evident that the organization concerned with policy making should keep it in mind that an enormous distortion of craft and performance comes along when the target buyers in the market are alien to the traditional context. In such a scenario, the contextual significance of a craft form can be kept intact if the targeted buyers can be made aware of the contextual and functional relevance of the folkloric element that they are consuming in its modernized version.
Initial Probing In Children Presenting At the Age of Three To Four Years
Authors: Israr Muhammad , Zahir Khalil Khan , Khattak Adnan , Khattak Irfanullah 
Published: February 2022

Objective: The aim of this study is to find out the ration of success in the initial probing for the congenital nasolacrimal duct obstruction at age 25th month to 60th month.
Methodology: The study was prospective non-comparative interventional case series. The study included 59 eyes of 47 patients who visited the Ophthalmology HMC Peshawar in 2020. The patients were labelled as CNLDO with history of epiphora and or discharge since birth or first few days of life. The diagnosis was confirmed with evaluation in which it was assessed that there is no other associated adnexal issue like conjunctively congestion. Examination also included tear meniscus height and resurge test.
Results: In prospective non-comparative interventional case series 52 eyes of 41 patients between the ages of 25 to 60 months with CNLDO were probed. Most of the patients were females i.e. 27. Most of the obstructions were of complex type i.e. 32 while 20 patients were of membranous type. Patients with bilateral CNLDO were 11. Successes ratio of probing in membranous type of obstruction was 90% i.e. 18 eyes got cured while two eyes needed repeated probing. While in case of complex obstruction the success ratio was, 32.2 % i.e. only 10 patients got cured out of 32 patients. Overall success ratio was 54% i.e 28 of 54.
Conclusion: Children presenting with congenial nasolacrimal duct obstruction in older ages should be probed initially.
Rate of Serum Electrolyte Derangement among Pakistani Children Having Acute Diarrhea and Dehydration K.P.K North Population Base Study (Pakistan)
Authors: Khan Muhammad Qasim , Ullah Kiramat , Ahmad Khalil , Rehman Sijad Ur , Khan Abbas Ali , Ullah Inayat , Khan Qasim , Din Qiam Ud 
Published: February 2022

Purpose: To study serum electrolyte derangements among children with acute diarrhea presenting with dehydration.
Methodology: Cross-sectional and descriptive study in department of Pediatrics, MMC Hospital, Mardan (Pakistan) for from 01-02-2020 to 31-10-2020. A total of 390 children having acute diarrhea with dehydration were included. Five milliliters (5mls) of blood was drawn and estimation of serum Sodium and potassium levels were done.
Findings: In 390 cases, 218 (55.9%) were males while 1 72 (44.1%) were females. The mean age was 2.5±1.5 years. Out of 390 cases, 2(0.51%) had no dehydration, some dehydration was noted in 218 (55.9%) cases while 170 (43.59%) cases had severe dehydration. Hypernatremia was noted in 218 (55.9%) cases and hypokalemia was noted in 77(19.74%) cases.
Conclusion: High rate of hyponatremia and hypokalemia was seen in our study in children with acute diarrhea and dehydration. Hyponatremia and hypokalemia was significantly associated with age, gender and grades of dehydration.
Pengaruh Penggunaan Software Treker Terhadap Hasil Belajar Fisika Mahasiswa Pada Pokok Bahasan Viskositas Fluida
Authors: Fahrudin Ahmad 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan software treker terhadap hasil belajar fisika mahasiswa pada pokok bahasan viskositas fluida. Sampel dalam penelitian ini yaitu mahasiswa semster satu prodi teknika Akademi Maritim Cirebon. Metode penelitian yang digunakan yaitu one group pretest-posttest design dengan teknik analisis paired sample t-test. Sebelum dilakukan pembelajaran menggunakan menggunakan software treker untuk menganalisis vidio viskositas fluida, mahasiswa diberikan pre-test untuk mengetahui kemampuan awal mahasiswa mengenai pokok bahasan yang akan disampaikan. Setelah dilakuakn pembelajaran menggunakan software treker untuk menganalisis vidio viskositas fluida, mahasiswa diberika post-test untuk mengetahui keberhasilan proses pembelajaran dan mengukur hasil belajar mahasiswa terhadap materi yang diajarkan. Berdasarkan hasil penelitian diperoleh skor rata-rata hasil belajar mengalami kenaikan sebesar 25 dengan nilai N-gain 0,63 atau pada katagori sedang. Hasil tersebut menunjukkan bahwa pembelajaran dengan menggunakan software tracker dapat meningkatkan hasil belajar mahasiswa dengan baik. Hal ini juga didukung dengan hasil dari analisis paired sample t-test diperoleh nilai signifikasi sebesar 0,00 , yang memberikan arti bahwa terdapat pengaruh yang signifikan pada pembelajaran menggunakan bantuan software treker terhadap hasil belajar fisika mahasiswa pada pokok bahasan viskositas fluida.
Polymer clips (Hem-o-lok®) for Renal Vessel Control in Laparoscopic Living Donor Nephrectomy: 12 years of experience in a Tertiary Care Center
Authors: Tena González Méndez Gerardo , Islas Miguel Alejandro Peña , Hernández Pañeda Humberto , Gabilondo Pliego Bernardo , Rodríguez Covarrubias Francisco Tomás 
Published: February 2022

Objective: To describe our experience using polymer clips (Hem-o-lok®) for renal vessel control in laparoscopic living donor nephrectomy (LLDN).
Materials and methods: We conducted a retrospective and descriptive analysis from our database of all minimally invasive living donor nephrectomies (hand-assisted and pure laparoscopic) performed from 2008 to 2020 in our institution. We included patients who underwent LLDN using polymer clips (Hem-o-lok®) for vascular control of renal arteries and veins, and whose clinical records were complete.
Results: 330 LLDN were performed, 183 (55.5%) were hand-assisted nephrectomies and 147 (44.5%) were pure laparoscopic nephrectomies. Mean warm ischemia time (WIT) was 3.98 minutes and median of estimated blood loss (EBL) was 100±140 ml. Four patients (1.2%) required conversion to an open procedure due to vascular injury. 31 complications (9.3%) were registered, of which 23 (6.9%) were non-life-threatening complications. No deaths nor loss of renal grafts were reported.
Limitations: the main drawbacks of this study are its retrospective nature, and that it is limited to only one center.
Originality and value: It is a study that questions the contraindication issued by the FDA for the use of polymer clips for vascular control in LLDN, demonstrating its use is a safe and effective option.
Conclusion
The use of polymer clips, specifically Hem-o-lok®, is a safe method for vascular control of the renal hilum vessels in laparoscopic living donor nephrectomies.
Applications and challenges of artificial intelligence in diagnostic
and interventional radiology
Authors: Waller Joseph , O’Connor Aisling , Raafat Eleeza , Amireh Ahmad , Dempsey John , Martin Clarissa , Umair Muhammad 
Published: February 2022

PurposeMachine learning (ML) and deep learning (DL) can be utilized in radiology to help diagnosis and for predicting management and outcomes based on certain image findings. DL utilizes convolutional neural networks (CNN) and may be used to classify imaging features. The objective of this literature review is to summarize recent publications highlighting the key ways in which ML and DL may be applied in radiology, along with solutions to the problems that this implementation may face.Material and methodsTwenty-one publications were selected from the primary literature through a PubMed search. The articles included in our review studied a range of applications of artificial intelligence in radiology.ResultsThe implementation of artificial intelligence in diagnostic and interventional radiology may improve image analysis, aid in diagnosis, as well as suggest appropriate interventions, clinical predictive modelling, and trainee education. Potential challenges include ethical concerns and the need for appropriate datasets with accurate labels and large sample sizes to train from. Additionally, the training data should be representative of the population to which the future ML platform will be applicable. Finally, machines do not disclose a statistical rationale when expounding on the task purpose, making them difficult to apply in medical imaging.ConclusionsAs radiologists report increased workload, utilization of artificial intelligence may provide improved outcomes in medical imaging by assisting, rather than guiding or replacing, radiologists. Further research should be done on the risks of AI implementation and how to most accurately validate the results.
PENGGUNAAN MADU UNTUK PENYEMBUHAN LUKA PADA PASIEN DIABETIC FOOT ULCER (DFU): LITERATURE REVIEW
Authors: Prima Ashar , Putra Qiantara , Yusrini Yusrini 
Published: February 2022

Abstrak
Tujuan: Tujuan penelitian ini adalah mengetahui efektifitas penggunaan madu sebagai dressing dalam penyembuhan luka pada pasien DFU berdasarkan literatur. Metode: Karya tulis ilmiah ini merupakan studi literatur pencarian menggunakan database elektronik google Schoolar, semantik Schoolar, dan PubMed. Kata kunci yang digunakan dalam pencarian adalah Diabetic Foot Ulcer atau Ulkus Kaki Diabetik, Honey atau Madu, Wound Healing atau Penyembuhan Luka. Kriteria inklusi yang digunakan dalam artikel dapat diakses, naskah full text, dalam bahasa Inggris dan bahasa Indonesia, gratis, tahun jurnal yang digunakan dibatasi 10 tahun terakhir. Hasil: ditemukan masing-masing 1 Pubmed, 2 google Schoolar, dari 3 artikel membahas penggunaan madu untuk penyembuhan luka pada pasien ulkus kaki diabetik. Hasil: Hasil studi literatur menunjukkan bahwa 3 artikel melaporkan bahwa madu dapat mempercepat penyembuhan luka pada pasien ulkus kaki diabetik karena madu dapat merangsang pertumbuhan granulasi, bersifat antibakteri, dan melembabkan luka. Kesimpulan: Berdasarkan hasil studi literatur, dapat disimpulkan bahwa dari 3 artikel yang menyatakan bahwa pemberian madu memiliki efektifitas terhadap penyembuhan luka pada pasien ulkus kaki diabetik.
Kata Kunci: Kaki Diabetik, Madu Penyembuhan Luka

Abstract
Objective: The purpose of this study was to determine the effectiveness of the use of honey for wound healing in diabetic foot ulcer patients based on a literature search Methods: This scientific paper was a search literature study using an electronic database google scholar, semantic scholar, and PubMed. The keywords used in the search were Diabetic Foot Ulcer or Diabetik Ulkus Pada Kaki, Honey or Madu, Wound healing or Penyembuhan Luka. The inclusion criteria used in the article are accessible, full-text manuscript, in English and Indonesian, free of charge, the journal year used is limited to the last 10 years, the results are found each 1 PubMed, 2 google scholar, from 3 articles discussing the use of honey for wound healing in diabetic foot ulcer patients. Results: The results of the literature study showed that the 3 articles reported that honey can accelerate wound healing in diabetic foot ulcer patients because honey can stimulate granulation growth, be antibacterial, and moisturize wounds.Conclusion: Based on the results of the literature study, it can be concluded that 3 articles stated that the administration of honey has an effect on wound healing in diabetic foot ulcer patients.
Keywords: Diabetic Foot Ulcer, Honey, Wound Healing