bluuebunny/crossref_metadata_2025_split huggingface dataset:
iORbase: A database for the prediction of the structures and functions of insect olfactory receptors
Authors: Li Qian , Zhang Yi‐Feng , Zhang Tian‐Min , Wan Jia‐Hui , Zhang Yu‐Dan , Yang Hui , Huang Yuan , Xu Chang , Li Gang , Lu Hui‐Meng 
Published: December 2022

AbstractInsect olfactory receptors (iORs) with atypical 7‐transmembrane domains, unlike Chordata olfactory receptors, are not in the GPCR protein family. iORs selectively bind to volatile ligands in the environment and affect essential insect behaviors. In this study, we constructed a new platform (iORbase, https://www.iorbase.com) for the structural and functional analysis of iORs based on a combined algorithm for gene annotation and protein structure prediction. Moreover, it provides the option to calculate the binding affinities and binding residues between iORs and pheromone molecules by virtual screening of docking. Furthermore, iORbase supports the automatic structural and functional prediction of user‐submitted iORs or pheromones. iORbase contains the well‐analyzed results of approximately 6 000 iORs and their 3D protein structures identified from 59 insect species and 2 077 insect pheromones from the literature, as well as approximately 12 million pairs of simulated interactions between functional iORs and pheromones. We also built 4 online modules, iORPDB, iInteraction, iModelTM, and iOdorTool to easily retrieve and visualize the 3D structures and interactions. iORbase can help greatly improve the experimental efficiency and success rate, identify new insecticide targets, or develop electronic nose technology. This study will shed light on the olfactory recognition mechanism and evolutionary characteristics from the perspectives of omics and macroevolution.
Fostering an inclusive workplace for LGBTQIA+ people in radiology and radiation oncology
Authors: Bird Alix , Zavaletta Vaz , Carroll Evelyn F , McGinnis Hirschel , Newsome Janice , Gichoya Judy , Oakden‐Rayner Lauren 
Published: December 2022

SummaryThe inclusion and celebration of LGBTQIA+ staff in radiology and radiation oncology departments is crucial in developing a diverse and thriving workplace. Despite the substantial social change in Australia, LGBTQIA+ people still experience harassment and exclusion, negatively impacting their well‐being and workplace productivity. We need to be proactive in creating policies that are properly implemented and translate to a safe and inclusive space for marginalised groups. In this work, we outline the role we all can play in creating inclusive environments, for both individuals and leaders working in radiology and radiation oncology. We can learn how to avoid normative assumptions about gender and sexuality, respect people's identities and speak out against witnessed discrimination or slights. Robust policies are needed to protect LGBTQIA+ members from discrimination and provide equal access across other pertinent parts of work life such as leave entitlements, representation in data collection and safe bathroom access. We all deserve to feel safe and respected at work and further effort is needed to ensure this extends to LGBTQIA+ staff in the radiology and radiation oncology workforces.
Ants as mealybug detectors: a novel tool for monitoring Planococcus ficus infestation based on ant behaviour
Authors: Castracani Cristina , Giannetti Daniele , Spotti Fiorenza A. , Schifani Enrico , Ghizzoni Martina , Delaiti Marco , Penner Francesco , Leonardi Stefano , Mori Alessandra , Ioriatti Claudio , Grasso Donato A. 
Published: December 2022

Abstract
Vineyards are economically valuable agroecosystems that have spread to all continents. As such, sustainable management of their pests is an important goal. Mealybugs are serious pests of vines with Planococcus ficus (VMB) being the most problematic worldwide. Mealybugs are attended by different ant species, whose trophobiotic relationship is often considered damaging since some ant species may offer effective protection from natural enemies in exchange for honeydew.
We tested whether this trophobiosis can be used as a VMB monitoring tool, developing a protocol to evaluate infestation on the plants based on ant behaviour (Ant method). We compared this new protocol with the conventional one, consisting in visual counting of VMBs on infested leaves (Leaf method).
Our results demonstrated that the Ant method yielded significant advantages over the Leaf method by: (i) allowing to detect VMB infestation on individual plants much earlier; and (ii) allowing to keep track of VMB presence after pest treatments.
The Ant method is proposed as a valid complementary tool for integrated pest management in vineyards and its successful achievement encourage searching for further agricultural contexts in which ants may be revaluated as a monitoring tool.
The effect of changing dialysate bicarbonate concentration on serum bicarbonate, body weight and normalized nitrogen appearance rate
Authors: Law Steven , Davenport Andrew 
Published: December 2022

AbstractIntroductionMost hemodialysis machines deliver a fixed bicarbonate concentration. Higher concentrations may improve acidosis, but risk post‐hemodialysis alkalosis, whereas lower concentrations potentially increase acidosis but reduce alkalosis. We reviewed the effects of lowering dialysate bicarbonate.MethodsWe reviewed peri‐dialysis chemistries in patients switching to a lower bicarbonate dialysate at 4 time points over 19 months.ResultsWe studied 126 patients, mean age 63.7 ± 16.3 years, 57.9% males. Post‐hemodialysis alkalosis fell from 1.6 to 0.3% sessions, but pre‐hemodialysis acidosis increased from 11.9 to 23.8% sessions (p = 0.005) reducing dialysate bicarbonate from 32 to 28 mmol/L. After 3 months, pre‐hemodialysis serum bicarbonate fell (21.1 ± 2.3 to 19.8 ± 2.2 mmol/L), and post‐hemodialysis (24.9 ± 2.1 to 22.5 ± 2.0 mmol/L, p < 0.001) with a fall in pre‐hemodialysis weight from 74.6 ± 20.7 to 71.7 ± 18.2 kg, normalized protein nitrogen accumulation rate 0.8 ± 0.28 to 0.77 ± 0.2 g/kg/day, p < 0.05, and serum albumin 39.7 ± 4.2 to 37.7 ± 4.9 g/L, p < 0.001. Thereafter, apart from pre‐ and post‐hemodialysis serum bicarbonate, weight and normalized protein nitrogen accumulation stabilized, although albumin remained lower (37.6 ± 4.0 g/L, p < 0.001). On multivariate logistic analysis, serum bicarbonate increased more with lower pre‐hemodialysis bicarbonate standardized coefficient β 0.5 (95% confidence interval −0.6 to −0.42), increased normalized protein nitrogen accumulation β 0.2 (0.96 to 2.38), p < 0.001, and session time β 0.09, (0.47 to 5.98), p < 0.022, and less with lower dialysate bicarbonate 0.0–0.23 (−1.54 to −0.74), p < 0.001.ConclusionIncreases in SE‐Bic with hemodialysis, depend on the bicarbonate gradient, session time and nPNA. Lower D‐Bic reduces post‐hemodialysis alkalosis but increases pre‐hemodialysis acidosis and may initially have adverse effects on weight and normalized protein nitrogen accumulation.
Mirror, mirror, on the social media … WeChat Moments usage and negative body image among female college students: Evidence from ecological momentary assessment data
Authors: Yu Mengke , Sun Xiaomin , Xu Yan , Liu Zhenzhen , Wu Yi , Yang Shuting , Luo Fang 
Published: December 2022

AbstractNegative body image is prevalent among women and may lead to physical and mental health problems. Social media—including China's most popular platform, WeChat Moments—aggregates multiple aspects of appearance‐related pressure and therefore is an important risk factor for negative body image. The current study examines the relationship between WeChat Moments usage and body image among female college students and the mediating mechanism of body surveillance. A sample of 151 female college students completed a 7‐day ecological momentary assessment (EMA), responded to three surveys per day, and provided a total of 2949 EMA responses. We used multilevel structural equation modeling (MSEM) to examine the hypothesized models at both the between‐ and within‐individual levels. The results showed that both overall WeChat Moments usage and appearance‐related exposure on WeChat Moments were inversely and indirectly related to body image through the mediating role of body surveillance at the between‐individual level. However, both overall WeChat Moments usage and appearance‐related exposure on WeChat Moments were positively and indirectly related to body image through body surveillance at the within‐individual level. Our findings indicate that WeChat Moments usage is associated with college women's body image differently at the between‐ and within‐individual level, and body surveillance serves as a crucial underlying mechanism.
Acute gastric twist after laparoscopic sleeve gastrectomy: A case series
Authors: Chamaa Bilal , Mouawad Christian , Dahboul Houssam , El Feghali Elie , Kazan Daniel , Sleilati Fadi 
Published: December 2022

AbstractIntroductionLaparoscopic sleeve gastrectomy (LSG) has become the most performed bariatric procedure. Like any surgical intervention, LSG is not free from complications. One of the rarest complications is gastric sleeve stenosis, caused by either stricture or axial rotation of the stomach (twisted gastric tube). There is no consensus on the management of such a complication due to several underlying mechanisms and different timings of presentation.MethodsBetween July 1, 2021 and December 31, 2021, we encountered three cases of acute gastric twist following LSG, and all of them required surgical intervention. All data (imaging results, operative reports and videos, discharge summaries, etc.) were retrospectively collected and analyzed after obtaining patients' informed consent.ResultsWe report three cases of acute gastric twist post‐sleeve gastrectomy, diagnosed by different imaging modalities which showed localized distal gastric twist. All patients underwent exploratory laparoscopy which confirmed gastric sleeve twist. Gastropexy by fixation of the gastric tube to the transverse mesocolon was done in the first case which presented a localized partial distal twist, and a gastro‐jejunal anastomosis proximal to the gastric twist was performed in the two other cases to bypass the obstruction. All of them had excellent postoperative results and a total symptomatic resolution.ConclusionWe considered gastric tube fixation to the transverse mesocolon as a feasible option when the twist is local and partial. We also presented a new surgical modality to treat local complete distal gastric twist by a single gastro‐jejunal latero‐lateral anastomosis proximal to the twist, which seems safe and effective. The best method to treat such a complication is to prevent it by giving special attention to the different technical aspects of LSG.
Mouse vaginal development with lateral enlargement at late embryonic stages and caudal elongation after birth
Authors: Harada Masayo , Akita Keiichi 
Published: December 2022

AbstractMüllerian ducts give rise to the oviducts, uterus, cervix, and vagina. During female reproductive tract development in mice, the bilateral Müllerian duct epithelium grows caudally until reaching the urogenital sinus epithelium. This is followed by further caudal growth with the reduction of the urogenital sinus epithelium. Finally, the vaginal epithelium of adult mice is entirely derived from the Müllerian duct epithelium. Here, we explored the mechanisms underlying mouse vaginal development via cell proliferation, apoptosis, and lineage analyses. We found that at the late embryonic stages, apoptosis occurred at the attachment site of bilateral Müllerian duct epithelia below the cervix, resulting in bilateral lumen traffic. The Müllerian duct epithelium was enclosed by the urogenital sinus epithelium at their boundary region on embryonic day (E) 16.5, whereas the Müllerian duct epithelium encased the urogenital sinus epithelium at postnatal day (P) 0 through lateral enlargement. Lateral Müllerian duct enlargement was accompanied by focal ERK activation within the curved epithelial tips and the specific localization of mitotic nuclei on the luminal side of the Müllerian duct epithelial layer at E17.5. Descent of the Müllerian duct epithelium and shortening of the urogenital sinus epithelium occurred rapidly after birth, accompanied by cell proliferation in the Müllerian duct epithelium and its peripheral mesenchymal tissues as well as intense apoptosis in the urogenital sinus epithelium around their boundary region. Urogenital sinus epithelium was localized at the base of the vagina at P7. In conclusion, the mouse vagina develops laterally at the late embryonic stages and caudally after birth.
Diversity of cortical bone morphology in anuran amphibians
Authors: Kondo Yoshiaki , Iwamoto Rina , Takahashi Takumi , Suganuma Kaito , Kato Hideaki , Nakamura Hiroaki , Yukita Akira 
Published: December 2022

AbstractThe cortical bones of mammals, birds, and reptiles are composed of a complex of woven bone and lamellar bone (fibrolamellar bone) organized into a variety of different patterns; however, it remains unclear whether amphibians possess similar structures. Importantly, to understand the evolutionary process of limb bones in tetrapods, it is necessary to compare the bone structure of amphibians (aquatic to terrestrial) with that of amniotes (mostly terrestrial). Therefore, this study compared the cortical bones in the long bones of several frog species before and after metamorphosis. Using micro‐computed tomography (CT), we found that the cortical bones in the fibrolamellar bone of Xenopus tropicalis (Pipoidea superfamily) and Lithobates catesbeianus (Ranoidea superfamily) froglets are dense, whereas those of Ceratophrys cranwelli (Hyloidea superfamily) are porous. To clarify whether these features are common to their superfamily or sister group, four other frog species were examined. Histochemical analyses revealed porous cortical bones in C. ornata and Lepidobatrachus laevis (belonging to the same family, Ceratophryidae, as C. cranwelli). However, the cortical bones of Dryophytes japonicus (Hylidae, a sister group of Ceratophryidae in the Hyloidea superfamily), Microhyla okinavensis (Microhylidae, independent of the Hyloidea superfamily), and Pleurodeles waltl, a newt as an outgroup of anurans, are dense with no observed cavities. Our findings demonstrate that at least three members of the Ceratophryidae family have porous cortical bones similar to those of reptiles, birds, and mammals, suggesting that the process of fibrolamellar bone formation arose evolutionarily in amphibians and is conserved in the common ancestor of amniotes.
Digoxigenin‐labeled RNA probes for untranslated regions enable the isoform‐specific gene expression analysis of myosin heavy chains in whole‐mount in situ hybridization
Authors: Tanji Masafumi , Wada Keitaro , Sakamoto Keita , Ono Yudai , Inui Masafumi 
Published: December 2022

AbstractMyosin heavy chains (MyHCs), which are encoded by myosin heavy chain (Myh) genes, are the most abundant proteins in myofiber. Among the 11 sarcomeric Myh isoform genes in the mammalian genome, seven are mainly expressed in skeletal muscle. Myh genes/MyHC proteins share a common role as force producing units with highly conserved sequences, but have distinct spatio‐temporal expression patterns. As such, the expression patterns of Myh genes/MyHC proteins are considered as molecular signatures of specific fiber types or the regenerative status of mammalian skeletal muscles. Immunohistochemistry is widely used for identifying MyHC expression patterns; however, this method is costly and is not ideal for whole‐mount samples, such as embryos. In situ hybridization (ISH) is another versatile method for the analysis of gene expression, but is not commonly applied for Myh genes, partly because of the highly homologous sequences of Myh genes. Here we demonstrate that an ISH analysis with the untranslated region (UTR) sequence of Myh genes is cost‐effective and specific method for analyzing the Myh gene expression in whole‐mount samples. Digoxigenin (DIG)‐labeled antisense probes for UTR sequences, but not for protein coding sequences, specifically detected the expression patterns of respective Myh isoform genes in both embryo and adult skeletal muscle tissues. UTR probes also revealed the isoform gene‐specific polarized localization of Myh mRNAs in embryonic myofibers, which implied a novel mRNA distribution mechanism. Our data suggested that the DIG‐labeled UTR probe is a cost‐effective and versatile method to specifically detect skeletal muscle Myh genes in a whole‐mount analysis.
Competencies for dental public health specialists: A thematic analysis
Authors: Malekmohammadi Mahsa , Ghasemi Hadi , Khoshnevisan Mohammad H. , Hosseini Fakhrolsadat 
Published: December 2022

AbstractIntroductionCompetency frameworks have been used to accurately guide the training and assessment of professionals. Dental Public Health professionals require a variety of skills beyond clinical aspects to meet ongoing social, economic, epidemiologic, technological, etc. developments. The purpose of this study was to develop a primary competency framework for dental public health (DPH) professionals by reviewing existing documents that can be modified by authorities based on their needs.Materials and MethodsTo identify DPH competencies, first a literature review of current postgraduate DPH competencies was conducted in PubMed, Scopus, Google Scholar, and Google from May to June 2021. All English language documents addressing DPH competencies were included and transferred to MAXQDA software. Next, DPH competency domains were extracted and defined, using Clarke and Braun's six‐step qualitative thematic analysis method.ResultsIn total, 206 English documents were retrieved. After exclusion of 201 documents due to being duplicate or not related in screening stages, five full‐text English documents describing competencies of DPH specialists from the United Kingdom, the United States, Australia and New Zealand, Canada, and Ireland were reviewed. Thematic analysis led to the provision of a framework consisting of all mentioned competencies in the reviewed documents including nine domains in education, research, management, policy, communication, leadership, professionalism, oral health status, and oral health services.ConclusionThe proposed primary framework covers all competency domains and, as a comprehensive tool, can be used as a guide by local, national, and international authorities to develop their own frameworks for training and evaluating the DPH workforce.
Monitoring sedimentary areas from mine waste products with Sentinel‐2 satellite images: A case study in theSEof Spain
Authors: Pereira Inés , Alcalde‐Aparicio Sara , Ferrer‐Julià Montserrat , Carreño María Francisca , García‐Meléndez Eduardo 
Published: December 2022

AbstractTorrential rainfall regimes, among others, are the origin of accelerated soil erosion. The Spanish southeastern Mediterranean region is characterised by an arid climate regime affected by extreme erosion episodes with an important loss of sediments. Soil erosion effects are even more noticeable in areas where soil has been anthropically degraded, as in the mining district ofSierra Minera de Cartagena. The present research focuses on monitoring and mapping the changes in the sediment distribution of iron oxides and hydroxyl (OH−) bearing minerals caused by a cold drop known in Spanish as 'DANA' in September 2019 on theRambla del Beal. This shortramblais fed by sediments from its drainage basin and by mining residues, irrigating a wide agricultural area. When discharges overflow theramblachannel, residues spread over its floodplain and reach the ecological protected coastal lagoonMar Menor. The objective of the study was mapping the mineral distribution of the mining materials eroded from the source areas and sedimented inRambla del Bealduring a DANA. The study was carried out using a pre‐ and a post‐DANA image from the Sentinel‐2 satellite. After masking vegetation, urban areas and water bodies, different band ratios (B4/B3, B11/B12, B8A/B6) and a Spectral Angle Mapper (SAM) classification were applied. Sediment deposits were identified in wider areas after the DANA. Iron oxides increased their extension by 11.08% in the central area (B3/B4 with R2of 0.84) and hydroxyl‐bearing minerals increased by 8.95% in theRambla del Beal's headwaters (B11/B12 withR2of 0.71). The SAM classification (with a 0.1 rad threshold and an overall accuracy of 87.33%) allowed the differentiation and classification of two ferric iron oxides (haematite and goethite) and one iron hydrous sulphate mineral (jarosite). Additionally, band ratio images were spatially overlaid with the soil land uses map layer of the cadastre in order to plot the land uses most affected by the transported sediments during the DANA. These results highlighted agricultural land as the areas (land uses) most affected by iron oxides deposition, as oxidation processes occur more rapidly in these areas. However, grassland and scrubland were the areas with the highest content of hydroxyl‐bearing minerals, as water is accumulated in these places, which favours hydrolysis reactions.HighlightsTorrential events can relocate large volumes of contaminated sediments from former mining areas.Sentinel‐2 allows monitoring mine waste iron‐sulphate changes caused by weathering alteration.Spatial mineralogical pattern in sediments is controlled by geomorphology and flood dynamics.The proposed digital image analysis allows mapping short‐term evolution of mine waste sediments.
Duration of epileptic seizure types: A data‐driven approach
Authors: Meritam Larsen Pirgit , Wüstenhagen Stephan , Terney Daniella , Gardella Elena , Aurlien Harald , Beniczky Sándor 
Published: December 2022

AbstractObjectiveTo determine the duration of epileptic seizure types in patients who did not undergo withdrawal of antiseizure medication.MethodsFrom a large, structured database of 11 919 consecutive, routine video‐electroencephalograpy (EEG) recordings, labeled using the SCORE (Standardized Computer‐Based Organized Reporting of EEG) system, we extracted and analyzed 2742 seizures. For each seizure type we determined median duration and range after removal of outliers (2.5–97.5 percentile). We used surface electromyography (EMG) for accurate measurement of short motor seizures.ResultsMyoclonic seizures last <150 ms, epileptic spasms 0.4–2 s, tonic seizures 1.5–36 s, atonic seizures 0.1–12,5 s, when measured using surface EMG. Generalized clonic seizures last 1–24 s. Typical absence seizures are rarely longer than 30 s (2.75–26.5 s) and atypical absences last 2–100 s. In our patients, the duration of focal aware (median: 27 s; 1.25–166 s) and impaired awareness seizures (median: 42.5 s; 9.5–271 s) was shorter than reported previously in patients undergoing withdrawal of antiseizure medication. All focal seizures terminated within 10 min. Median duration of generalized tonic–clonic seizures was 79.5 s (57–102 s) and of focal‐to‐bilateral tonic–clonic seizures was 103.5 (77.5–237 s). All tonic–clonic seizures terminated within 5 min.SignificanceThis comprehensive list of seizure durations provides important information for characterizing seizures and diagnosing patients with epilepsy. The upper limits of seizure durations are helpful in early recognition of imminent status epilepticus.
Do fund managers time momentum? Evidence from mutual fund and hedge fund returns
Authors: Wang Feifei , Zheng Lingling 
Published: December 2022

AbstractBy examining fund returns we find strong evidence that both hedge funds and mutual funds trade on momentum. Moreover, the average hedge fund has modest momentum timing skill, trading more aggressively when momentum profits are higher, while the average mutual fund does not. Momentum trading alone does not translate into superior performance. However, funds with momentum timing ability significantly outperform and the risk‐adjusted‐return‐difference between the top and the bottom timers is around 1.7% (1.3%) per year for hedge (mutual) funds. We provide further evidence that dynamic momentum strategies enhance fund performance, and momentum timing skills vary considerably with fund investment styles.