bluuebunny/crossref_metadata_2025_split huggingface dataset:
Copper oxide wire particles effective against gastrointestinal nematodes in adult alpacas during a randomized clinical trial
Authors: Needleman Abigail L. , Wright Megan C. , Schaefer John J. , Videla Ricardo , Lear Andrea S. 
Published: September 2022

Abstract

OBJECTIVE
To determine whether copper oxide wire particles (COWP) administered as an oral bolus effectively decrease fecal gastrointestinal nematode (GIN) egg counts in adult alpacas.

ANIMALS
57 adult alpacas.

PROCEDURES
A double-blind clinical trial was performed during the months of April through August 2019. Adult alpacas enrolled in the trial were administered 2 g of COWP or a placebo control capsule PO on day 0 and day 45. On day 0 and at 15-day intervals, fecal samples were collected, and Modified McMaster fecal egg counts (FEC) were performed as well as physical examinations, including FAMACHA scoring and body condition scoring (BCS). Hematocrits were measured in 30-day intervals (days 0, 30, 60, and 90). Results were compared across groups.

RESULTS
A significant decrease in mean FEC was observed in the COWP-treated group over time, compared with the placebo group. Mean BCS, FAMACHA score, and Hct did not differ significantly between groups. No clinical evidence of copper toxicosis was observed.

CLINICAL RELEVANCE
Oral administration of COWP was determined to be a safe and effective method of reducing GIN FEC in adult alpacas.
Interventional Therapy in Refractory Hypertension: An Update
Authors: Clement Alexandra , Tudurachi Bogdan , Benchea Laura , Sascău Radu A. , Stătescu Cristian 
Published: September 2022

Abstract
Hypertension represents a major public health issue, affecting about 26% of the world's population. It is the most common cardiovascular risk factor worldwide, with a prevalence that continues to grow. Among this hypertensive population, a critical subgroup is that of patients with resistant hypertension. For subjects with truly resistant hypertension, the next step after nonpharmacological interventions and drug therapy is represented by interventional treatment. However, implementing an interventional approach in resistant hypertension represents a real challenge. The decision needs to be undertaken in multidisciplinary teams, which must include a specialist in hypertension, and it is not routinely recommended. The main device-based therapies for hypertension are represented by carotid baroreceptor stimulation, renal denervation, and the creation of an arteriovenous fistula. Until 2018, there was an important controversy on the beneficial effects of renal sympathetic denervation. One cannot ignore, however, the positive results of interventional therapy for treatment-resistant hypertension obtained in different trials conducted on a large number of patients. A significant reduction in blood pressure values and an improvement in cardiovascular outcomes could be attained with interventional therapy through a rigorous selection of patients.
Efeitos citogenotóxicos das infusões de costus spicatus sobre células meristemáticas de allium cepa
Authors: Leal Claudia de Faria , De Alemida Daiane Maria , Ribeiro Lília Rosário 
Published: September 2022

Introdução: Costus spicatus (Jacq.) é uma espécie herbácea cujo uso medicinal é indicado para fins depurativos, adstringentes, diuréticos e também para o tratamento de algumas doenças do trato urinário e malária. Considerando a escassez de informações sobre a toxicidade das infusões dessa planta, este trabalho teve como objetivo verificar os possíveis efeitos citogenótoxicos das infusões de C. spicatus sobre células meristemáticas de A. cepa. Material e Métodos: Foram realizadas avaliações microscópicas utilizando três concentrações de infusões (0,9; 4,5; 9,0 g/L) preparadas a partir das folhas in natura de Costus spicatus (Jacq.). Como controle negativo foi utilizada água destilada, e metil metano-sulfonato (MMS) (10 μg/mL) como controle positivo. Resultados: A análise citogenética evidenciou aumento significativo do índice mitótico e das alterações cromossômicas (p<0,05) em todos os tratamentos onde foram utilizadas as infusões de C. spicatus. Foi observado também que as infusões foram capazes de provocar distúrbios no fuso mitótico das células meristemáticas de A.cepa, independente da concentração. Conclusão: As infusões de C. spicatus provocaram efeitos citogenotóxicos sobre células meristemáticas de A. cepa.
Predviđanje cena kriptovaluta upotrebom ARIMA i ARIMAKS modela
Authors: Glavaš Predrag 
Published: September 2022

Ovaj rad se bavi predviđanjem cena Dodžkoin, Šiba Inu i Idena kriptovaluta u kratkom i srednjem roku upotrebom ARIMA i ARIMAKS modela. Podaci su preuzimani sa različitih javno dostupnih izvora, vremenske serije pretprocesirane kako bi se osigurala stacionarnost, a parametri modela birani pretragom kombinacija parametara i putem auto arima funkcije. Testirani su različiti intervali predviđanja, a modeli evaluirani Akaike informacionim kriterijumom i greškom u apsolutnom procentu. Za kratkoročna predviđanja ARIMA model je imao grešku od oko 3.5%, ARIMAKS od 7 do 19%, dok su se za srednji rok oba modela pokazala kao loša.
KONTROLA OŠTRINE FOTOGRAFIJA DOBIJENIH POMOĆU ZADNJIH KAMERA MOBILNIH TELEFONA
Authors: Stojanović Teodora , Jurič Ivana 
Published: September 2022

Analiziranje i određivanje razlika i sličnosti između zadnjih kamera pet različitih modela mobilnih telefona. Vrši se upoređivanje i kontrola oštrine fotografija dobijenih mobilnim telefonima koji su detaljnije opisani u daljem tekstu. Upotrebom specijalnih test karti za testiranje i Imatest softvera, dolazi se do kvantitativnih rezultata koji pružaju informacije vezane za kvalitet oštrine.
Hubungan Kausalitas antara Sentimen Investor dan Pasar Keuangan Indonesia
Authors: Elizabeth Inge Pratiwi  , Elsa Imelda  
Published: September 2022

This study aims to see the causal relationship that occurs between investor sentiment-based google search and the Indonesian stock-bond market in 2020. The test used in this study is a combined test between the quantile test to see the effect of investor sentiment on optimistic (pessimistic) conditions and the Granger causality test to detect the causal relationship that occurs between variables. The results of the study found that there was a one-way relationship between investor sentiment and the Indonesian stock market where investor sentiment affects the stock market. Interestingly, in the bond market, causal relationship between variables can’t be found. This study also found that the causal relationship between investor sentiment variables and financial markets only occurs when the optimistic and pessimistic conditions of investors aren't in extreme conditions.
Consumer Perceptions of a Shingles Infograph Intervention and Vaccination Plans in Community Pharmacy Settings
Authors: Devraj Radhika , Wilhelm Miranda , Deshpande Maithili 
Published: September 2022

Background: Cost and lack of knowledge are key barriers to improving shingles vaccination rates in community pharmacies. A health literacy (HL) tailored infograph intervention addressing these barriers can enhance consumer interest in shingles vaccinations.
Objectives: The objectives were to: 1) design a health literacy tailored shingles infograph addressing cost and knowledge about vaccination barriers, 2) determine consumer perceptions of infograph usefulness, and 3) determine factors associated with shingles vaccination plans.
Methods: An infograph addressing the study objectives, and a 22-item self-administered questionnaire assessing shingles vaccine awareness, HL, infograph usefulness, and vaccination plans were designed. The infograph was pilot tested with pharmacists and two community-based focus groups. Inclusion criteria consisted of age-eligible consumers at one chain and three independent community pharmacies. Consenting participants first reviewed the infograph and then completed the survey. Descriptive statistics and multivariable logistic regression analyses were performed.
Results: Of the 422 eligible consumers approached, 112 participated in the study, with 55.4% from the chain pharmacies. Participants were female (56%), white (94%), between 50-70 years old (77%), had adequate HL (96%) and aware of the shingles vaccine (87%). While only 8% of the respondents considered vaccinating on the survey date, 46% considered it in the future, and 29% planned to in the next six months. The infograph was useful (90%) in recognizing vaccination need, was readable (95.5%), and understandable (96%). Consumers who found the infograph useful were significantly more likely to have vaccination plans (OR= 4.06, CI: 1.37 – 11.9, p=0.016).
Conclusion: A shingles vaccine infograph focused on key barriers to vaccination was well-received and useful in promoting consumers’ vaccination plans.
Delayed Speech Dengan dan Tanpa Gangguan Pendengaran pada Anak Usia 6 Bulan sampai 3 Tahun di Jala Puspa RSPAL Dr. Ramelan Surabaya Periode 2017-2020
Authors: Halim Anthony Stephen , Limantara Edward , Diarsvitri Wienta 
Published: September 2022

Late or untreated delayed speech can be a risk for social, emotional, behavioral and cognitive problems in adulthood. Delayed speech is associated with hearing loss, mental retardation, autism spectrum disorder (OSD), bilingualism, and lack of psychosocial stimuli. Objectives: To determine the prevalence of delayed speech with and without hearing loss in children aged six months until three years. Methods: This study used 872 medical records of delayed speech children aged six months until three years with and without hearing loss in 2017 until 2020 period at Jala Puspa RSPAL Dr. Ramelan, Surabaya. The presence or absence of hearing loss was examined using Brainstem Evoked Response Audiometry (BERA), and the degree of hearing loss was examined using Auditory Steady-State Response (ASSR) test. Results: From a total of 872 medical records data studied, 558 (64.0%) were males and 314 (36.0%) were females. The majority (44.8%) of delayed speech children were from the two-year age group. There were 565 (64.8%) delayed speech children with hearing loss and 307 (35.2%) without hearing loss. Of those with hearing loss, 48.0% showed a profound degree. There was an increase in delayed speech children without hearing loss compared to those with hearing loss, from 1:2.04 in 2017 to 1:1.12 in 2020. Conclusion: There was an increase in delayed speech children without hearing loss compared to those with hearing loss.Keywords: ASSR, BERA, delayed speech, hearing loss
Uji Kesesuaian Hasil Pemeriksaan Sedimen Urine Metode Shih-Yung pada Volume Urine 10 mL dan 5 mL
Authors: Niawaty Putri , Rikarni Rikarni , Yulia Dwi 
Published: September 2022

Microscopic examination of urine sediment using shih-yung system requires 10ml urine volume. Pediatric patients and kidney disease patients with oliguria difficult to get 10mL urine samples, so it needs to be studied to determine the accuracy of results with smaller sample volumes. Objectives: To analyze agreement of urine sediment examination using Shih-yung system in 10 mL and 5 mL urine volume. Methods: This study was a cross-sectional analysis of 37 urine specimens that met inclusion and exclusion criteria at the central laboratory of Dr. M. Djamil Hospital from July to September 2020. Examination of erythrocyte sediment, leukocyte sediment, and non-hyaline cast using Shih-yung system was done in 10 mL and 5 mL urine volume. Data were analyzed using kappa reliability/agreement test and significant if p<0.05. Results: Agreement test of erythrocyte sediment examination using Shih-yung system in 10ml and 5mL urine volume were moderate significantly (κ=0.600; p<0.05), agreement of leukocyte sediment examination were moderate significantly (κ=0.571; p<0.05), and agreement of nonhialin cast examination were substantial significantly (κ=0.767; p<0.05). Conclusion: Agreement test of erythrocyte and leukocyte sediment examination in 10ml and 5mL urine volume is moderate, so 5ml urine volume was not recommended. Manual examination with microscope and difference in urine sample volume causing difference sediment concentration and amount of sediment per microscope field of view.Keywords: Shih-yung, urine sediment, urine volume
Junctional Bradikardia pada Pasien Hiperkalemia
Authors: Suwari Cokorda Istri Padmi , Puradipa Bayu , Wulandari Ni Luh Eka Sriayu 
Published: September 2022

Hyperkalemia is a life-threatening electrolyte abnormality resulting in cardiac arrhythmia. Hyperkalemia may also cause bradycardia with junctional rhythm. However, the prevalence of hyperkalemia accompanying symptomatic bradycardia has only been explored in a few case reports. Thus we present a case of hyperkalemia with uncommon ECG findings. It has been reported that a 76 years old woman with type 2 diabetes mellitus, hyperkalemia and suspected coronary artery disease complaining about palpitation. Electrocardiography (ECG) showed junctional bradycardia with tall T wave and laboratory examination showed mild hyperkalemia (5.8 mmol/L). After one day of observation, severe hypotension was detected. Unexpectedly the cardiac rhythm was returned into the sinus after correction of hyperkalemia using calcium gluconate, insulin, dextrose, and salbutamol. As serum potassium level rises, sinoatrial and atrioventricular conduction was blocked, causing escape rhythm (junctional escape rhythm). In hyperkalemia, cardiotoxicity can be caused by an increase in resting membrane potential, decreased depolarization and duration of depolarization. When detected on ECG, hyperkalemia should be treated urgently and important to identify underlying causes or precipitating factors of hyperkalemia. Sinus node dysfunction is not excluded in this case. Hyperkalemia can present a bradycardia junctional rhythm. Although the increasing serum potassium levels were low, hyperkalemia may have affected the conduction system leading to the ECG changes.Keywords: hyperkalemia, junctional bradycardia, symptomatic bradycardia
Flight Simulation and Drag Prediction for a Pitching-Accelerating Hypersonic Reentry Vehicle
Authors: Khalil Mostafa , Abdel-Gawad Mohamed S. , Ahmed Mahmoud Y. M. 
Published: September 2022

A nonwinged reentry vehicle, such as the upper stage of a ballistic missile, endures harsh aerodynamic loads during the phase of reentry. This phase is characterized by sophisticated flight phenomena including hypersonic speed, continuous variation of surrounding atmospheric conditions, and pitching transient vehicle motion. During the flight in this descent phase, drag is considered the dominant aerodynamic force where accurate prediction is crucial as far as reliable trajectory prediction and mission planning are concerned. This study aims to investigate drag on a generic bi-cone nonwinged reentry vehicle resembling an upper stage of a ballistic missile during descent. This is done by using both trajectory prediction and numerical simulation of vehicle–air interaction. To obtain the vehicle dynamics and instantaneous flight conditions through descending phase, a three-degree-of-freedom pitch flight trajectory model is utilized starting from point of separation. It was concluded that the vehicle experiences small-amplitude pitching motion while descending from about 90 to 30 km and accelerating in a hypersonic regime (Mach 5.7–7). Drag is then calculated via time-dependent numerical simulations. The results show the flowfield pattern evolution in addition to the temporal variation of drag on the vehicle during the flight phase in concern.
Nonlinear parabolic problems with an unknown source function and their applications for modelling and control of filtration processes
Authors: Гольдман Н.Л. 
Published: September 2022

Работа связана с изучением нелинейных параболических систем, возникающих при моделировании и управлении нестационарными процессами фильтрации в подземной гидродинамике. Одна из постановок является системой, которая включает в себя краевую задачу второго рода для квазилинейного параболического уравнения с неизвестной функцией источника в правой части, а также уравнение изменения по времени этой функции. В другой постановке рассматривается проблема управления этой системой с управляющим воздействием граничного режима. Данные постановки существенно отличаются от обычных краевых задач и задач управления для параболических уравнений, в которых предполагается, что все входные данные должны быть заданы. Полученные в работе результаты представляют не только теоретический интерес, они имеют практическое значение для исследования различных фильтрационных процессов. Приведены некоторые примеры таких приложений, связанных с движением жидкости в трещиновато-пористых средах.
The work is connected with study of nonlinear parabolic systems arising in the modelling and control of nonstationary filtration processes in underground hydrodynamics. One of such statements is formulated as a system that involves the boundary value problem of the second kind for a quasilinear parabolic equation with an unknown source function in the right-hand side and, moreover, involves an additional equation for a time dependence of this function. In the other statement we consider control of this system controlled by the boundary regime. These statements essentially differ from usual boundary value problems and control problems for parabolic equations, where all the input data must be given. The obtained results have not only the theoretical interest but they are also important for investigation of various filtration processes. Some examples of such applications connected with fluid flow in the fractured porous media are discussed.
HUBUNGAN MOTIVASI PERAWAT DAN SUPERVISI KEPALA RUANGAN TERHADAP PENDOKUMENTASIAN DISCHARGE PLANNING DI RUMAH SAKIT TK. II KARTIKA HUSADA
Authors: Mikha Mikha 
Published: September 2022

Latar Belakang: Discharge planning adalah proses dimana tim rumah sakit yang berhubungan dengan pasien mengatur pengembalian pasien ke rumah mereka atau pindah ke tempat perawatan lain. Adapun yang mempengaruhi pelaksanaan discharge planning yaitu motivasi perawat dan supervisi kepala ruangan. Tujuan: Mengetahui hubungan antara motivasi perawat dan supervisi kepala ruangan dengan kinerja perawat dalam pendokumentasian discharge planning. Metode: Ada hubungan kuantitatif dengan menggunakan cross sectional Instrumen penelitian meliputi angket skala likert dan checklist untuk observasi. Analisis data univariat dan bivariat.Hasil: Dari hasil uji analitik, kinerja perawat dalam pencatatan discharge plan dipengaruhi oleh motivasi dan supervisi yang dilakukan oleh kepala ruangan. Kesimpulan: Terdapat korelasi antara motivasi perawat dan supervisi kepala ruangan terhadap pendokumentasian discharge planning, akan tetapi korelasinya berlawanan arah.
FAKTOR-FAKTOR YANG MEMENGARUHI KURANG MINATNYA PEREMPUAN USIA SUBUR TERHADAP PEMERIKSAAN IVA: Literature Review
Authors: Astikasari Diah 
Published: September 2022

Kanker serviks yang disebabkan oleh virus HPV (Human Papiloma Virus) menyerang wania usia subur dan juga merupakan kankerdengan kejadian kasus terbesar. Untuk mengetahui faktor-faktor yang dapat memengaruhi kurang minat perempuan usiasubur terhadap pemeriksaan IVA.Jenis penelitian ini menggunakan literature review dengan teknik analisa menggunakan PiCoT dan artikel diperoleh dari databaseGoogle Schoolar, Pubmed dan Sciencedirect dengan menggunakan kata kunci dalam bahasa inggris “the factors that affecting,women of childbearing age, visual inspection with acetic acid, VIA examination” dan bahasa indonesia “ faktor-faktor yangmemengaruhi, perempuan usia subur, inspeksi visual asam asetat, pemeriksaan IV”. Kemudian dilakukan esktraksi databerdasarkan nama pengarang, tahun, negara, tujuan, reponden, desain, temuan.
Expanding Agency. Women, Race and the Dissemination of Modern Architecture
Authors: James-Chakraborty Kathleen 
Published: September 2022

Expanding Agency: Women, Race and the Dissemination of Modern Architecture is a five-year research project funded by a European Research Council Advanced Grant. It explores the role that women and members of ethnic minorities, primarily African Americans, played in transmitting modern architecture and design internationally between 1920 and 1970. Strands devoted to patronage, journalism, entrepreneurship, and institution building offer alternatives to accounts that focus primarily on architects. This approach expands our understanding of who had agency in this important story and more generally in shaping the built environment. Taking a global view that stresses comparisons across continents also helps build a more nuanced history of how architecture, landscape architecture, interior decoration, and the design of furnishing were transformed by new ideas that emanated from a multiplicity of sources. This in turn can help support a more diverse profession that, in the wake of #metoo and Black Lives Matter, is better prepared to engage with a broad public, including to address such social challenges as sustainability and the integration of migrants.
Early deaths associated with community-acquired and healthcare-associated bloodstream infections: a population-based study, Finland, 2004 to 2018
Authors: Kontula Keiju SK , Skogberg Kirsi , Ollgren Jukka , Järvinen Asko , Lyytikäinen Outi 
Published: September 2022

Background
Bloodstream infections (BSI) cause substantial morbidity and mortality.

Aim
We explored the role of causative pathogens and patient characteristics on the outcome of community-acquired (CA) and healthcare-associated (HA) BSI, with particular interest in early death.

Methods
We used national register data to identify all BSI in Finland during 2004–18. We determined the origin of BSI, patients´ underlying comorbidities and deaths within 2 or 30 days from specimen collection. A time-dependent Cox model was applied to evaluate the impact of patient characteristics and causative pathogens on the hazard for death at different time points.

Results
A total of 173,715 BSI were identified; 22,474 (12.9%) were fatal within 30 days and, of these, 6,392 (28.4%) occurred within 2 days (7.9 deaths/100,000 population). The 2-day case fatality rate of HA-BSI was higher than that of CA-BSI (5.4% vs 3.0%). Patients who died within 2 days were older than those alive on day 3 (76 vs 70 years) and had more severe comorbidities. Compared with other BSI, infections leading to death within 2 days were more often polymicrobial (11.8% vs 6.3%) and caused by Pseudomonas aeruginosa (6.2% vs 2.0%), fungi (2.9% vs 1.4%) and multidrug-resistant (MDR) pathogens (2.2% vs 1.8%), which were also predictors of death within 2 days in the model.

Conclusions
Overrepresentation of polymicrobial, fungal, P. aeruginosa and MDR aetiology among BSI leading to early death is challenging concerning the initial antimicrobial treatment. Our findings highlight the need for active prevention and prompt recognition of BSI and appropriate antimicrobial treatment.