bluuebunny/crossref_metadata_2025_split huggingface dataset:
The cold-stress responsive gene DREB1A involved in low-temperature tolerance in Xinjiang wild walnut
Authors: Han Liqun , Ma Kai , Zhao Yu , Mei Chuang , Mamat Aisajan , Wang Jixun , Qin Ling , He Tianming 
Published: September 2022

Background
Low-temperatures have the potential to be a serious problem for plants and can negatively affect the normal growth and development of walnuts. DREB1/CBF (Dehydration Responsive Element Binding Protein 1/C-repeat Binding Factor), one of the most direct transcription factors in response to low-temperature stress, may improve the resistance of plants to low-temperatures by regulating their functional genes. However, few studies have been conducted in walnut. The Xinjiang wild walnut is a rare wild plant found in China, with a large number of excellent trait genes, and is hardier than cultivated walnuts in Xinjiang.

Methods
In this work, we identified all of the DREB1 members from the walnut genome and analyzed their expression levels in different tissues and during low-temperature stress on the Xinjiang wild walnut. The JfDREB1A gene of the Xinjiang wild walnut was cloned and transformed into Arabidopsis thaliana for functional verification.

Results
There were five DREB1 transcription factors in the walnut genome. Among them, the relative expression level of the DREB1A gene was significantly higher than other members in the different tissues (root, stem, leaf) and was immediately un-regulated under low-temperature stress. The overexpression of the JfDREB1A gene increased the survival rates of transgenic Arabidopsis lines, mainly through maintaining the stability of cell membrane, decreasing the electrical conductivity and increasing the activities of antioxidant enzymes including superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT). Additionally, the expression levels of cold-inducible genes like AtKIN1, AtERD10, AtRD29A, AtCOR15A and AtCOR47, were significantly increased. These results showed that the JfDREB1A gene may play an important role in the response to cold stress of the Xinjiang wild walnut. This study contributes to our understanding of the molecular mechanism of the Xinjiang wild walnut’s response to low-temperature stress and will be beneficial for developing walnut cultivars with improved cold resistance.
Comparative Study of Changes in Inflammatory Markers on Hours of Exposure to Cement Dust
Authors: Nyebuchi Jonathan , Nwogu Arit Okechukwu , Jumbo Mieiwari Ibufubara , Adjekuko Collins Ohwonigho , Bartimaeus Ebirien-Agana S. 
Published: September 2022

Background: There has been a growing concern about the health of people exposed to cement dust.
Objective: This study was aimed at assessing the effect of cement dust on inflammatory markers on cement loaders with different duration of hourly exposure.
Methods: This is a cross-sectional study design conducted in Port Harcourt, Nigeria with 100 male cement workers grouped into 3 groups based on the hourly duration of cement dust exposure. Group 1 (27 subjects) was exposed to 1-5 daily hours; Group 2 (62 subjects), was exposed to 6-10 daily hours, and Group C (11 subjects), was exposed to more than 10 daily hours. The ELISA analysis of C-Reactive protein (CRP), IL-1β, and IL-10 was performed. The data generated were analyzed for mean and standard deviation by ANOVA.
Results: The CRP levels were 5.42 ± 4.72; 6.71 ± 4.96 and 9.04 ± 8.83 in groups 1, 2, and 3 respectively. The p-value was 0.1771 implying no significant difference. The IL-10 levels were 15.72 ± 12.58; 12.23 ± 10.12 and 11.83 ± 8.88 in groups 1, 2, and 3 respectively. The p-value was 0.3421 implying no significant difference. The IL-1β levels were 3.81 ± 1.02; 3.63 ± 1.36 and 3.91 ± 1.21 in groups 1, 2, and 3 respectively. The p-value was 0.7031 implying no significant difference.
Conclusion: The study has shown that hourly changes in exposure to cement dust don’t have an impact on the studied inflammatory markers among cement workers in Port Harcourt.
Laser‐Induced Secondary Crystallization of CsPbBr3 Perovskite Film for Robust and Low Threshold Amplified Spontaneous Emission
Authors: Shi Yueqing , Li Ruxue , Yin Guoxin , Zhang Xuanyu , Yu Xuanchi , Meng Bingheng , Wei Zhipeng , Chen Rui 
Published: September 2022

AbstractAll‐inorganic perovskite nanocrystals (NCs) have received extensive attention for next‐generation thin film devices due to their excellent optical properties, such as strong light absorption, high carrier mobility, and defect tolerance. However, significant challenges remain to obtain high‐quality perovskite thin films. Herein, a simple but effective post‐treatment by laser irradiation for CsPbBr3 NCs thin films is reported. Laser‐induced secondary crystallization is observed in CsPbBr3 NCs thin films after treatment. In addition, amplified spontaneous emission (ASE) with a low threshold (5.6 µJ cm−2) and a high gain value (743 cm–1) is achieved. Based on optical measurements, it is attributed to the low defect density, reduced Auger recombination, and weak exciton–phonon interactions, which greatly suppress the nonradiative recombination channels. The ASE from the film after treatment has a high characteristic temperature (134 K), showing a stable optical gain performance that maintains its intensity for 35 h at room temperature (and 12 h at 40 °C). Finally, the proof‐of‐concept demonstration of graphic coding is shown. This study deepens the understanding of the optical gain mechanism of CsPbBr3 perovskite films and provides a simple and convenient laser treatment that enables the fabrication of high‐quality CsPbBr3 perovskite thin films.
A Medium‐Bandgap Nonfullerene Acceptor Enabling Organic Photovoltaic Cells with 30% Efficiency under Indoor Artificial Light
Authors: Zhang Tao , An Cunbin , Xu Ye , Bi Pengqing , Chen Zhihao , Wang Jingwen , Yang Ni , Yang Yi , Xu Bowei , Yao Huifeng , Hao Xiaotao , Zhang Shaoqing , Hou Jianhui 
Published: September 2022

AbstractThe correlation between molecular structure and photovoltaic performance is lagging for constructing high‐performance indoor organic photovoltaic (OPV) cells. Herein, this relationship is investigated in depth by employing two medium‐bandgap nonfullerene acceptors (NFAs). The newly synthesized NFA of FTCCBr exhibits a similar bandgap and molecular energy level, but a much stronger dipole moment and larger average electrostatic potential (ESP) compared with ITCC. After blending with the polymer donor PB2, the PB2:ITCC and PB2:FTCCBr blends exhibit favorable bulk‐heterojunction morphologies and the same driving force, but the PB2:FTCCBr blend exhibits a large ESP difference. In OPV cells, the PB2:ITCC‐based device produces a power conversion efficiency (PCE) of 11.0%, whereas the PB2:FTCCBr‐based device gives an excellent PCE of 14.8% with an open‐circuit voltage (VOC) of 1.05 V, which is the highest value among OPV cells with VOC values above 1.0 V. When both acceptor‐based devices work under a 1000 lux of 3000 K light‐emitting diode, the PB2:ITCC‐based 1 cm2 device yields a good PCE of 25.4%; in contrast, the PB2:FTCCBr‐based 1 cm2 device outputs a record PCE of 30.2%. These results suggest that a large ESP offset in photovoltaic materials is important for achieving high‐performance OPV cells.
Chemical Welding of the Electrode–Electrolyte Interface by Zn‐Metal‐Initiated In Situ Gelation for Ultralong‐Life Zn‐Ion Batteries
Authors: Qin Yao , Li Hongfei , Han Cuiping , Mo Funian , Wang Xin 
Published: September 2022

AbstractA compatible and robust electrode–electrolyte interface is favorable in resolving the severe dendritic growth and side reactions of aqueous Zn‐ion batteries toward commercial‐standard lifespan and charging–discharging rate. Herein, a chemical welding strategy through in situ construction of a gel electrolyte that enables Zn‐ion batteries to achieve ultralong life and reversibility is reported. The gel electrolyte is spontaneously formed on the Zn anode surface by redox polymerization with the initiation of Zn metal. The direct participation of the Zn anode in the chemical synthesis of the gel electrolyte brings a well‐bonded and water‐poor electrode–electrolyte interface, which not only alleviates side reactions but also enables preferential (002) Zn deposition. The in situ symmetric cell thus prepared delivers an ultralong lifespan of 5100 h (>212 days), and a hybrid capacitor with the in situ electrolyte runs smoothly over 40 000 cycles at 20 A g−1. Even at an ultrahigh current density of 40 mA cm−2 and capacity of 40 mAh cm−2, the cell still operates stably for 240 h, alongside a high Zn utilization with 87% depth of discharge. The in situ gel electrolyte integrating robust interface and preparation of all‐in‐one cells demonstrate a commercializable path for aqueous Zn‐storage devices.
A One‐Step Ionic Liquid Interface‐to‐Bulk Modification for Stable Carbon‐Based CsPbI3 Perovskite Solar Cells with Efficiency Over 15%
Authors: Yin Ran , Wang Ke‐Xiang , Huo Xiao‐Nan , Sun Yan‐Sheng , Sun Wei‐Wei , Gao Yu‐Kun , You Ting‐Ting , Yin Peng‐Gang 
Published: September 2022

AbstractHole transport layer‐free, carbon‐based, all‐inorganic CsPbI3 perovskite solar cells (PSCs) have exhibited great potential in photovoltaic applications owing to their low cost and excellent thermal stability. However, the low power conversion efficiency (PCE) hampers its development, mainly due to the existence of defects inside the CsPbI3 film or at TiO2 electron transport layer/CsPbI3 interface. Herein, these issues were addressed through a facile TiO2 post‐treatment strategy using 1‐butyl‐3‐methylimidazole hexafluorophosphate (BMIMPF6) ionic liquid. First, BMIMPF6 can passivate TiO2/CsPbI3 interface defects by forming strong bond between the electron‐rich N atoms and uncoordinated ions. Second, BMIMPF6‐modified TiO2 shows reduced hydrophilicity, inducing decreased heterogeneous nucleation and is favorable for obtaining high‐quality CsPbI3 film. Thirdly, the non‐volatile BMIMPF6 can diffuse to the perovskite film surface during annealing, further passivating defects located at perovskite grain boundaries and surface. Based on this one‐step ionic liquid interface‐to‐bulk modification, the modified device achieves a champion PCE of 15.09%, which is 14% higher than the control device (13.27%). In addition, the modified device also shows enhanced long‐term stability, which remains 96% of initial PCE after 30 days storage in dry air. The work demonstrates the superiority of multifunctional ionic liquid applied to all‐inorganic carbon‐based PSCs, providing a guidance for its commercialization.
The Tuning of Exciton‐Phonon Coupling in Colloidal Nanocrystals by a Dielectric Medium
Authors: Meir Itay , Horani Faris , Zuri Shahar , Lifshitz Efrat 
Published: September 2022

AbstractHere, a thorough study is reported that exposes the influence of surfactants’ dielectric screening on the exciton energy and exciton‐phonon coupling in CdSe and CdSe/CdS colloidal quantum dots and nanoplatelets. The study follows the temperature dependence of the photoluminescence spectrum to monitor thermally activated exciton‐phonon interactions. The dependence of the exciton energy on temperature exhibits an anomalous point at ≈250 K, which coincides with the melting point of surfactant ligands (oleate molecules), an effect that is accompanied by a change in the dielectric constant. Interestingly, this anomalous effect gradually fades away upon increasing the shell thickness in CdSe/CdS derivatives. Furthermore, inspecting the exciton band's full‐width‐at‐half‐maximum (FWHM) dependence on temperature reveals the tuning of the optical phonon frequency when in direct contact with surfactant ligands. However, this effect is replaced by a surplus coupling to the phonon mode of the shell (CdS or CdSeS) when the thickest shell solely isolates the ligand dielectric screening. The study uncovers the impact of the dielectric screening on the optical properties of semiconductor nanocrystals, with an added value in the implementation of those materials in various optoelectronic, quantum, and tagging devices.
Wireless‐Powered Electrical Bandage Contact Lens for Facilitating Corneal Wound Healing
Authors: Wu Qianni , Yang Cheng , Chen Wan , Chen Kexin , Chen Hui‐jiuan , Liu Fanmao , Liu Dong , Lin Haotian , Xie Xi , Chen Weirong 
Published: September 2022

AbstractCorneal injury can lead to severe vision impairment or even blindness. Although numerous methods are developed to accelerate corneal wound healing, most of them are passive treatments that rarely participate in controlling endogenous cell behaviors or are incompatible with nontransparent bandage. In this work, a wireless‐powered electrical bandage contact lens (EBCL) is developed to generate a localized external electric field to accelerate corneal wound healing and vision recovery. The wireless electrical stimulation circuit employed a flower‐shaped layout design that can be compactly integrated on bandage contact lens without blocking the vision. The role of the external electric field in promoting corneal wound healing is examined in vitro, where the responses of directional migration and corneal cells alignment to the electric field are observed. The RNA sequencing (RNA‐seq) analysis indicates that the electrical stimulation can participate in controlling cell division, proliferation, and migration. Furthermore, the wireless EBCL is demonstrated to accelerate the completed recovery of corneal wounds on rabbits’ eyes by electrical stimulation, while the control group exhibits delayed recovery and obvious corneal defects. As a new generation of intelligent device, the wireless and patient‐friendly EBCL can provide a promising therapeutic strategy for ocular diseases.
Transcript Engineered Extracellular Vesicles Alleviate Alloreactive Dynamics in Renal Transplantation
Authors: Lin Jinwen , Lv Junhao , Yu Shiping , Chen Ying , Wang Huiping , Chen Jianghua 
Published: September 2022

AbstractDirect contact of membrane molecules and cytokine interactions orchestrate immune homeostasis. However, overcoming the threshold of distance and velocity barriers, and achieving adhesion mediated immune interaction remain difficult. Here, inspired by the natural chemotaxis of regulatory T cells, multifunctionalized FOXP3 genetic engineered extracellular vesicles, termed Foe‐TEVs, are designed, which display with adhesive molecules, regulatory cytokines, and coinhibitory contact molecules involving CTLA‐4 and PD‐1, by limited exogenous gene transduction. Foe‐TEVs effectively adhere to the tubular, endothelial, and glomerular regions of allogeneic injury in the renal allograft, mitigating cell death in situ and chronic fibrosis transition. Remarkably, transcript engineering reverses the tracking velocity of vesicles to a retained phenotype and enhanced arrest coefficient by a factor of 2.16, directly interacting and attenuating excessive allosensitization kinetics in adaptive lymphoid organs. In murine allogeneic transplantation, immune adhesive Foe‐TEVs alleviate pathological responses, restore renal function with well ordered ultrastructure and improved glomerular filtration rate, and prolong the survival period of the recipient from 30.16 to 92.81 days, demonstrating that the delivery of extracellular vesicles, genetically engineered for immune adhesive, is a promising strategy for the treatment of graft rejection.
Hijacking Self‐Assembly to Establish Intracellular Functional Nanoparticles
Authors: Liu Yang , Wang Yuchen , Wang Chao , Dong Tiejun , Xu Haiheng , Guo Yunfei , Zhao Xiaozhi , Hu Yiqiao , Wu Jinhui 
Published: September 2022

AbstractThe targeted transport of nanomedicines is often impeded by various biological events in the body. Viruses can hijack host cells and utilize intracellular transcription and translation biological events to achieve their replication. Inspired by this, a strategy to hijack endogenous products of biological events to assemble into intracellular functional nanoparticles is established. It has been shown that, following tumor vessel destruction therapy, injected cell permeable small molecule drugs bisphosphonate can hijack the hemorrhagic product iron and self‐assemble into peroxidase‐like nanoparticles within tumor‐infiltrating macrophages. Unlike free drugs, the generated intercellular nanoparticles can specifically stress mitochondria, resulting in immune activation of macrophages in vitro and polarizing tumor‐associated macrophages (TAMs) from immunosuppressive to tumoricidal and increasing the recruitment of T cells deep within tumor. The hijacking self‐assembly strategy significantly inhibits tumor growth compared with the treatment of vascular‐disrupting agents alone. Using bisphosphonate to hijack the metabolite associated with hemorrhage, iron, to fabricate functional nanoparticles within specific cells, which may open up new nanotechnology for drug delivery and small molecular drug development.
High‐Entropy and Superstructure‐Stabilized Layered Oxide Cathodes for Sodium‐Ion Batteries
Authors: Yao Libing , Zou Peichao , Wang Chunyang , Jiang Jiahao , Ma Lu , Tan Sha , Beyer Kevin A. , Xu Feng , Hu Enyuan , Xin Huolin L. 
Published: September 2022

AbstractLayered transition metal oxides are appealing cathodes for sodium‐ion batteries due to their overall advantages in energy density and cost. But their stabilities are usually compromised by the complicated phase transition and the oxygen redox, particularly when operating at high voltages, leading to poor structural stability and substantial capacity loss. Here an integrated strategy combing the high‐entropy design with the superlattice‐stabilization to extend the cycle life and enhance the rate capability of layered cathodes is reported. It is shown that the as‐prepared high‐entropy Na2/3Li1/6Fe1/6Co1/6Ni1/6Mn1/3O2 cathode enables a superlattice structure with Li/transition metal ordering and delivers excellent electrochemical performance that is not affected by the presence of phase transition and oxygen redox. It achieves a high reversible capacity (171.2 mAh g−1 at 0.1 C), a high energy density (531 Wh kg−1), extended cycling stability (89.3% capacity retention at 1 C for 90 cycles and 63.7% capacity retention at 5 C after 300 cycles), and excellent fast‐charging capability (78 mAh g−1 at 10 C). This strategy would inspire more rational designs that can be leveraged to improve the reliability of layered cathodes for secondary‐ion batteries.
An Organic Semiconductor Photoelectrochemical Tandem Cell for Solar Water Splitting
Authors: Zhang Dan , Cho Han‐Hee , Yum Jun‐Ho , Mensi Mounir , Sivula Kevin 
Published: September 2022

AbstractPhotoelectrochemical cells employing organic semiconductors (OS) are promising for solar‐to‐fuel conversion via water splitting. However, despite encouraging advances with the half reactions, complete overall water splitting remains a challenge. Herein, a robust organic photocathode operating in near‐neutral pH electrolyte by careful selections of a semiconducting polymer bulk heterojunction (BHJ) blend and organic charge‐selective layer is realized. The optimized photocathode produces a photocurrent density of >4 mA cm−2 at 0 V vs the reversible hydrogen electrode (VRHE) for solar water reduction with noticeable operational stability (retaining ≈90% of the initial performance over 6 h) at pH 9. Combining the optimized BHJ photocathode with a benchmark BHJ photoanode leads to the demonstration of a large‐area (2.4 cm2) organic photoelectrochemical tandem cell for complete solar water splitting, with a predicted solar‐to‐hydrogen (STH) conversion efficiency of 0.8%. Under unassisted two‐electrode operation (1 Sun illumination) a stabilized photocurrent of 0.6 mA and an STH of 0.3% are observed together with near unity Faradaic efficiency of H2 and O2 production.
Acceleration of thermal decomposition of molten nitrates by Cr in steel and promotion of this effect by halogens
Authors: Sun Ze , Luo Yuxin , Song Ping , Gao Xianyang 
Published: September 2022

AbstractMolten salts have been widely studied as the most common heat storage medium for concentrated solar power (CSP) plants. However, most studies have focused on the corrosiveness of molten salts, while this study innovatively reveals the role of stainless steel in promoting the decomposition of molten salts and the mechanism by which the halogen ions accelerate this process. Considering commercial Solar Salt as an example, the thermal stability, composition, and thermophysical properties of Solar Salt adding Cl−, Br−, and I− after contacting different stainless steel were analyzed. The results showed that Cr was the main reason for the decomposition of the molten salt, and Cl−, Br−, and I−, all accelerated the decomposition. Meanwhile, different halogen ions promoted the decomposition of molten salts through different mechanisms: oxide layer destruction and chain oxidation.
Arsenic trioxide and Erlotinib loaded in RGD‐modified nanoliposomes for targeted combination delivery to PC3 and PANC‐1 cell lines
Authors: Khosravani Fatemeh , Mir Hamed , Mirzaei Ali , Kobarfard Farzad , Bardania Hassan , Hosseini Ebrahim 
Published: September 2022

AbstractDuring the past few years, advances in drag delivery have provided many opportunities in the treatment of various diseases and cancer. Arsenic trioxide (ATO) and Erlotinib (Erlo) are two drugs, approved by the United States Food and Drug Administration to treat cancer, but their use is limited in terms of the toxicity of ATO and the low solubility of Erlo. This study aimed to prepare arginine‐glycine‐aspartic acid (RGD)‐decorated nanoliposomes (NLPs) containing Erlo and ATO (NLPs–ATO–Erlo–RGD) to increase the solubility and reduce the toxicity of Erlo and ATO for cancer treatment. The results of transmission electron microscopy and dynamic light scattering showed that NLPs were synthesized uniformly, with spherical shape morphology and particle sizes between 140 and 160 nm. High‐performance liquid chromatography and ICP–MS results showed that about 90% of the drug was loaded in the NLPs. In comparison with NLPs–ATO–Erlo, NLPs–ATO–Erlo–RGD demonstrated considerable toxicity against the αvβ3 overexpressing PC3 cell line in the MTT experiment. It had no effect on the PANC‐1 cell line. In addition, apoptosis assays using Annexin V/PI demonstrated that NLPs–ATO–Erlo–RGD generated the highest apoptotic rates in PC3 cells when compared with NLPs–ATO–Erlo and the combination of free ATO and Erlo. Furthermore, treatment with NLPs–ATO–Erlo–RGD in (p < 0.05) PC3 cell line significantly reduced EGFR level. It is concluded NLPs–ATO–Erlo–RGD as a novel drug delivery system may be a promising platform for the treatment of cancer.