bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seroprevalensi Rabies Pascavaksinasi pada Populasi Anjing di Kawasan Endemik Rabies di Kabupaten Sukabumi
Authors: Murtini Sri , Rotinsulu Dordia Anindita , Ridwan Yusuf , Lukman Denny Widaya , Zahid Abdul , Wicaksono Ardilasunu , Afiff Usamah , Asah Hilaliah  , Risqika Akla Velayati  , Sudarnika Etih , Santoso Koekoeh , Wijaya Agus 
Published: March 2022

Penelitian ini bertujuan untuk mengevaluasi hasil vaksinasi rabies dan membandingkan kenaikan titer antibodi yang terbentuk di Kecamatan Cisolok dan Jampang Tengah sebagai Kawasan endemik rabies Kabupaten Sukabumi dan mengasosiasikan titer antibodi yang terbentuk dengan umur, jenis kelamin, dan cara pemeliharaan anjing yang diperiksa . Sebanyak 211 anjing diamati pada studi ini. Sampel serum prevaksinasi dan pascavaksinasi diambil dan selanjutnya diuji dengan uji ELISA tidak langsung untuk mengetahui titer antibodinya. Data titer antibodi dari masing-masing sampel dianalisis secara deskriptif, sedangkan asosiasi umur, jenis kelamin, dan cara pemeliharaan dengan titer antibodi yang terbentuk pascavaksinasi dihitung menggunakan uji chi-square. Hasil pengujian menunjukkan seroprevalensi rabies di Kecamatan Cisolok dan Jampang Tengah sebelum vaksinasi adalah 17,3% dan 2,6% dengan titer 0,58 EU/mL dan 0,55 EU/mL, sedangkan seroprevalensi setelah vaksinasi menjadi 62,5% dan 93% dengan titer 1,29 EU/mL dan 1,33 EU/mL. Variabel umur, jenis kelamin, dan cara pemeliharaan tidak berasosiasi nyata dengan peningkatan titer antibodi rabies setelah vaksinasi. Hasil studi menyimpulkan bahwa seroprevalensi rabies di kawasan endemik rabies di Kabupaten Sukabumi meningkat setelah dilakukan vaksinasi dari sebelumnya 11% menjadi 75,8%, dengan nilai peningkatan titer (Δ titer) sebesar 1,09 EU/mL.
Aspirina, Clopidogrel e Hemorragia Gastrointestinal: Qual a Evidência?
Authors: Ferreira-Alves Eduarda , Lamas Joana , Rocha-Cruz Mariana 
Published: March 2022

INTRODUÇÃO: O ácido acetilsalicílico (AAS), vulgarmente designado por aspirina, é sobejamente utilizado na prevenção secundária de eventos cardiovasculares, assim como o clopidogrel, outro antiagregante plaquetário. É conhecida a associação do AAS ao aumento do risco de complicações gastrointestinais (GI). No entanto, existe alguma evidência científica que sugere uma possível diminuição deste risco com clopidogrel comparativamente com o uso de AAS. Assim, é comum a substituição do AAS pelo clopidogrel em situações de hemorragia. O nosso objetivo foi avaliar a eventual superioridade do clopidogrel na redução do risco hemorrágico GI em doentes a fazer AAS ou clopidogrel em prevenção cardiovascular secundária.MÉTODOS: Foi realizada uma pesquisa bibliográfica de artigos publicados entre janeiro de 2000 e agosto de 2020, nas línguas portuguesa e inglesa e indexadas na PubMed, Cochrane, DARE, National Guideline Clearinghouse, Canadian Medical Association Practice Guidelines Infobase e Evidence Based Medicine Online. Os termos MeSH utilizados foram ‘clopidogrel’, ‘aspirin’ e ‘gastrointestinal hemorrhage’. A atribuição dos níveis de evidência e forças de recomendação baseou-se na escala Strength of Recommendation Taxonomy (SORT).RESULTADOS: A pesquisa inicial encontrou 278 artigos, dos quais foram incluídos na revisão dez: uma revisão sistemática, quatro ensaios clínicos randomizados, três estudos coortes retrospetivos, um estudo coorte prospetivo e um estudo caso-controlo prospetivo.CONCLUSÃO: Os estudos com maior nível de evidência apontam para a inexistência de superioridade do clopidogrel em relação ao AAS no que concerne a complicações GI (SORT B). Outros sugerem mesmo que a utilização de AAS associada a inibidores da bomba de protões (IBP) reduz este risco comparativamente ao clopidogrel isolado. Na ausência de consenso entre os diversos estudos, sugere-se a realização de novos estudos, nomeadamente ensaios clínicos randomizados, dirigidos especificamente para esta temática.
Portuguese National Pedagogical Plan for Anesthesiology Residents’ Evaluation: The Participants’ Rating
Authors: Maio Matos Francisco , Ramos Martins Mafalda , Norte Gustavo 
Published: March 2022

INTRODUCTION: Simulation in anesthesiology has been considered a crucial complementary training for residents of this medical specialty. A National Pedagogical Plan of the Biomedical Simulation Center from Centro Hospitalar e Universitário de Coimbra was designed according to the curricular objectives defined by the Portuguese Board of Anesthesiology. The objective of this study is to analyze the evaluation of the programmatic contents included in the simulation courses from the participants’ point of view.METHODS: Post-course confidential questionnaires were answered by all the anesthesiology residents that attended the different modules. All the questions were answered on a 0-10 scale. This study was conducted at the Biomedical Simulation Center from Centro Hospitalar e Universitário de Coimbra, Portugal, from February 2011 to March 2018.RESULTS: A total of 344 questionnaires were answered. The students considered that all the topics included in the simulation courses are important for the training during residency, being basic pharmacology in anesthesiology (Year I) the less important one being classified with 5.03 (IC 95% 4.83-5.22). All the programmatic contents included in the simulation module of the year IV were classified by the residents with importance higher than 8. This last year was the one where the importance of the topics is all numerically higher than in the other years.CONCLUSION: Given the importance attributed by the residents to the programmatic content included in the simulation courses, we can conclude that the design of the courses was appropriate to the needs and the goals of the anesthesiology residents, as a complement of their internship.
Parsonage-Turner Syndrome Revisited: Four Case Reports and Literature Review
Authors: Monteiro Sara , Silva Gomes Diogo , Moura Nuno , Sarmento Marco , Cartucho António 
Published: March 2022

INTRODUCTION: Parsonage-Turner syndrome is a rare disease characterized by acute and severe shoulder pain followed by upper extremity paralysis, that is severely underdiagnosed in clinical practice. The objective is to describe four illustrative clinical cases and provide a summary review of the topic.CASE REPORTS: Four patients (aged 56 to 84 years-old) diagnosed with Parsonage-Turner syndrome were followed up for functional recovery and patient satisfaction after conservative treatment. Despite presenting with typical sudden-onset pain in the shoulder region, followed by weakness in the shoulder/arm, all patients had delayed diagnosis. Only one patient reported a preceding viral infection, which is the most common trigger. Pain subsided after 3-8 days, but shoulder/arm weakness persisted. All patients recovered, totally or partially, with pain management and physical therapy. Recovery took 6-15 months and was monitored through clinical evaluation and electromyography. At last follow-up, all patients were satisfied.CONCLUSION: Parsonage-Turner syndrome has a higher incidence than previously assumed and is frequently underdiagnosed. It must be considered in the differential diagnosis of the painful shoulder, especially if muscle weakness is present. Despite being a self-limited condition, recovery is usually slow, and a prompt diagnosis is key for patient’s reassurance and starting adequate supportive treatment.
Ertapenem-Induced Delirium
Authors: Bilreiro Mariana , Marote Correia Luís 
Published: March 2022

Neurotoxicity is an unusual iatrogenic effect associated with carbapenems, typically manifested as seizures or hyperactive delirium. We present an 89-year-old female patient with a medical history of hypertension and chronic kidney disease who was admitted for acute tracheobronchitis and anemia related to diverticular disease. As a complication, she developed acute cystitis caused by extended spectrum ß-lactamases producing Klebsiella pneumoniae, so intravenous ertapenem was started. On the second day of antibiotic therapy, the patient manifested visual hallucinations followed by an inattentive and lethargic state suggestive of a hypoactive delirium. An ertapenem-induced neurotoxicity was suspected. Upon substitution by meropenem, the patient improved, and symptom reversal occurred after 72 hours. We present a review of ertapenem-induced hallucinations and address pharmacokinetics aspects namely renal dysfunction and hypoalbuminemia that could potentiate encephalopathy. Although rare, clinicians should be aware of non-seizure ertapenem related neurotoxicity. Ready recognition can lead to rapid improvement and prevent dire outcomes.
Pengaruh Penambahan Lidah Buaya (Aloe barbadensis Miller) pada Minyak Goreng Bekas terhadap Kadar Bilangan Asam
Authors: Salim Maulidiyah , Ratnawati Gervacia Jenny , Nuswantoro Ari 
Published: March 2022

Minyak goreng bekas memiliki kadar bilangan asam yang tinggi dan dapat menyebabkan kerusakan minyak tersebut. Tujuan dari penelitian ini adalah untuk mengetahui apakah ada pengaruh penambahan lidah buaya (Aloe barbadensis Miller) pada minyak goreng bekas terhadap kadar bilangan asam. Desain penelitian yang digunakan adalah eksperimen semu, menggunakan Teknik purposive sampling. Sampel adalah minyak goreng yang telah mengalami proses penggorengan secara berulang yang dibagi menjadi ke dalam 4 kelompok perlakuan dan masing-masing 6 pengulangan sehingga total sampel menjadi 24. Kadar asam lemak bebas diperiksa dengan menggunakan metode alkalimetri. Nilai rata-rata kadar bilangan asam pada kelompok yang terdiri dari tanpa penambahan lidah buaya, dengan penambahan lidah buaya 25 gram, dengan penambahan lidah buaya 50 gram, dan dengan penambahan lidah buaya 75 gram berturut-turut adalah 0,17%, 0,15%, 0,11%, dan 0,09%. Hasil uji regresi linier sederhana memberikan nilai probabilitas 0,000 (p < 0,05) sehingga dinyatakan ada pengaruh penambahan lidah buaya pada minyak goreng bekas terhadap kadar bilangan asam.
Evaluation of whey protein concentrate as a functional ingredient on quality of goat milk rasogolla - an Indian dessert
Authors: Mishra Kuldeep , Pinto Suneeta , Jambukiya Hitesh , Prajapati J P 
Published: March 2022

In the literature, a variety of dairy products are made from goat milk; however, information related to the manufacture of rasogolla from goat milk is very scant. During preliminary trials, it was observed that chhena prepared from goat milk was not suitable for the preparation of rasogolla because it has a very soft and sticky body that is difficult to handle. Therefore, this investigation was conducted to formulate an acceptable quality goat milk rasogolla using whey protein concentrate (WPC) as a functional ingredient. Chhena (also known as Indian cottage cheese, a heat- and acid-coagulated indigenous dairy product) was prepared from fresh Surati goat milk (3.5% fat/8.5% milk solids-not-fat (MSNF). Twelve batches of rasogolla were prepared from chhena coagulated at three temperatures viz. 75, 80 and 85⁰C containing WPC at 4 levels (i.e., 0, 0.25, 0.50 and 0.75% w/w of milk). Rasogolla prepared from chhena containing 0.50% WPC in milk and coagulated at 80°C was preferred the most with respect to all the sensory attributes evaluated. It had significantly (P<0.05) highest sucrose content, i.e., 35.73% and a higher sugar absorption ratio, i.e., 2.63, compared to all the other experimental samples. The composition of drained samples of goat milk rasogolla was as follows: moisture 50.07%; protein 7.04%; fat 6.44%; ash 0.45% and sucrose 35.73%. The pH was 6.34 and acidity was 0.76% lactic acid. Based on the results obtained in this study, a method was developed for the preparation of acceptable quality goat milk chhena and rasogolla.
Rice cv. HUR105 response to zinc fertilizer combined with microbial consortia and cow dung grown in the eastern plain of Uttar Pradesh, India
Authors: Prajapati Jaya , Yadav Janardan , Prajapati Brajkishor 
Published: March 2022

The solubility and bioavailability of zinc in the soil determinethe efficiency of Zn fertilizers. A two-year (2018 and 2019) field experiment was performed to study the effectiveness of Zn sources combined with Zn solubilizing microorganisms, ZSM (Acinetobacter calcoaceticus + Pantoea agglomerans) and cow dung, in rice cv. HUR105 in alluvial soil at the Agriculture Research Farm, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh. Among various treatments, the treatment (T8) 9.8 kg ZnO ha-1 with ZSM showed better grain and straw yields. However, 25.0 kg ZnSHH ha-1+ ZSM (T6) was found to be statistically comparable to the treatment (T8). The addition of cow dung (CD) decreased the grain yield in T11 ( 9.8 kg ZnO ha-1 + ZSM + 200 kg CD ha-1) and T12 (14.6 kg ZnO ha-1 + ZSM + 200 kg CD ha-1), except the treatment (T10) 4.9 kg ZnO + ZSM + 200 kg CD ha-1. Partial factor productivity of applied Zn varied from 347.2 to 1762.2 and 369.6 to 1855.6 kg grain kg-1 Zn, physiological Zn efficiency varied from 487.4 to 2075.3 and 775.5 and 2035.2 kg grain kg-1 Zn absorbed, agronomic use efficiency of Zn ranged from 20.1 to 189.6 and 28.7 to 180 kg grain kg-1 Zn, the recovery efficiency of Zn fertilizer varied from 3.58 to 11.9% and 3.57 to 11.8% among the treatments in both seasons, respectively. The maximum gross and net return were documented by T8- 9.8 kg ZnO ha-1 + ZSM, and 23.9% and 28.5% over the control due to higher grain yields.
Postępowanie w przedmiocie wymierzania kar pieniężnych na podstawie Prawa ochrony środowiska – wybrane uwagi
Authors: Gruszecki Krzysztof 
Published: March 2022

Jedną z podstawowych zasad ochrony środowiska jest dyrektywa „zanieczyszczający płaci”, mająca umocowanie w postanowieniach art. 7 ustawy z dnia 27 kwietnia 2001 r. – Prawo ochrony środowiska. Środkiem prawnym służącym jej realizacji są kary pieniężne wymierzane na podstawie art. 298 p.o.ś. za naruszenie warunków korzystania ze środowiska. Sposób ustalania wysokości kar został określony w art. 305 i 305a p.o.ś. Zasady postępowania w przedmiocie ich wymierzania zawarto jednak także w Kodeksie postępowania administracyjnego, którego art. 189f precyzuje, kiedy należy odstąpić od wymierzenia kary. Rozwiązanie to odnosi się również do kar wymierzanych na podstawie p.o.ś., w praktyce więc zachodzi konieczność łącznego stosowania rozwiązań wynikających z k.p.a. i p.o.ś. W artykule omówiono zatem przesłanki, które uzasadniają odstąpienie od wymierzenia kary pieniężnej za naruszenie warunków korzystania ze środowiska, a w podsumowaniu wskazano, że taki dualizm nie jest dobry, dlatego przepisy prawa w tym zakresie powinny zostać uporządkowane.
ORAL PRESENTATION: Eagle Syndrome: The Forgotten Entity
Authors: Sobani Muhamad Ariff , Mat Barhan Noor Shairah , Ahmad Kailani Abdul Azim Al-Abrar , Rahim Norazila Abdul , Mansor Masaany 
Published: March 2022

Elongated styloid process or Eagle syndrome is a rare condition presenting with a wide range of symptoms including throat pain, foreign body sensation, neck pain and ear pain. Establishing a diagnosis requires a high index of suspicion and understanding of this entity by the physician. Computed tomography (CT) is the gold standard to diagnose Eagle syndrome. Conservative medical treatment with analgesics, oral steroids and anticonvulsants are offered in patients who refused surgery. The mainstay of treatment is surgical resection via intraoral or cervical approaches. We describe a rare case of bilateral Eagle syndrome in a 46-year-old female who was presented with chronic foreign body sensation in the throat but aggravated following fish bone ingestion. Flexible nasopharyngolaryngoscopy (FNPLS) and cervical x-ray did not reveal any foreign body and the patient was treated conservatively. Incidentally, a cervical x-ray also revealed an elongated styloid process bilaterally. Upon follow-up, the patient was still symptomatic. Thus, a CT scan with contrast of the neck was requested, which reported no foreign body, but the presence of bilateral elongated styloid process suggesting Eagle Syndrome. The patient was subjected to transoral endoscopic assisted bilateral styloidectomy following tonsillectomy. There was a complete resolution of the symptoms postoperatively. This approach is recommended to avoid external scarring and minimize postoperative pain. Eagle syndrome is diagnosed based on a combination of physical examination and radiological findings. The treatment options may vary based on the severity of symptoms.International Journal of Human and Health Sciences Supplementary Issue: 2022 Page: S14
What Do Older Canadians Think They Need to Walk Well?
Authors: Abou-Sharkh Ahmed , Mate Kedar K. V. , Inceer Mehmet , Morais José A. , Morin Suzanne N. , Mayo Nancy E. 
Published: March 2022

Purpose: To identify older Canadians’ perception of the importance of expert-generated elements of walking quality, and the contributors to and consequences of perceived walking quality. Method: Cross-sectional survey of 649 adults was conducted through a commercial participant panel, Hosted in Canada Surveys. Results: Of the 649 respondents, 75% were between 65 and 74 years old (25% ≥ 75) and 49% were women. The most important elements were foot, ankle, hip, and knee mobility with little difference in ranks across walking perception (Fr χ12 = 5.0, p > 0.05). People who were older by a decade were more likely to report poorer walking (POR: 1.4; 95% CI: 1.0, 1.7), as were women compared to men, and people who used a walking aid compared to none. Lung disease showed the highest association with a perception of not walking well (POR: 7.2; 95% CI: 3.7, 14.2). The odds of being willing to pay more for a technology to improve walking were always greater for those with a lower perception of their walking quality. Conclusions: People who perceived their walking quality as poor were more likely to report poorer health and were willing to pay more for a technology to improve walking. This supports the opportunity of leveraging wearable technologies to improve walking.
PSYCHOCORRECTION OF PSYCHOLOGICAL MALADAPTATION AMONG CIVIL SERVANTS
Authors: Sydorenko O. О. 
Published: March 2022

Introduction. Strict performance requirements applied to civil servants, a high level of mental stress and of responsibility at the workplace can be considered as risk factors leading to the formation of a wide range of maladaptive reactions and states among civil servants - starting with specific mosaic domains and ending with nosologically defined mental disorders of neurotic genesis or psychosomatic illnesses, resulting in a state of psychological maladaptation.
The purpose. Develop a program of psychological correction based on the detection of states of psychological maladaptation in civil servants.
Materials and methods of the research. The main group consisted of 78 civil servants with the domain of psychological maladaptation, the experimental group consisted of 81 civil servants, among whose members no domain of psychological maladaptation was detected.
Results. States of psychological maladaptation among civil servants were conceptualized as a holistic clinical and psychological, and socio-psychological phenomenon that has a multicomponent origin of biopsychosocial nature. We have identified the peculiarities of professional deformation and the psychoemotional state among the civil servants, and have determined the specifics of their mutual influence and the role of each parameter in the origin of the development of psychological maladaptation among the persons concerned.
Conclusions. The study found that the essential factor in the formation of states of psychological maladaptation is the disparity between the level of stress caused by the working environment of a civil servant and his personal and adaptive resource base.
Development of Modified Kato Katz Kit as Laboratory Scale Prototype for Early Detection of Soil-Transmitted Helminths (STHs) Infection
Authors: Rifqoh Rifqoh , Kustiningsih Yayuk , Cahyono Jujuk Anton 
Published: March 2022

<span lang="EN-US">Early detection of </span><span lang="IN">Soil-Transmitted Helminths (STHs)</span><span lang="IN"> infection</span><span lang="EN-US"> in laboratory </span><span lang="IN">medical facilities </span><span lang="EN-US">is one of the government's efforts in </span><span lang="IN">its elimination</span><span lang="EN-US">. Government regulations recommend Kato</span><span lang="IN">-</span><span lang="EN-US">Katz's </span><span lang="IN">quantitative </span><span lang="EN-US">method </span><span lang="IN">for</span><span lang="IN">the diagnosis </span><span lang="EN-US">of </span><span lang="IN">STHs infection</span><span lang="EN-US">. Kato</span><span lang="IN">-</span><span lang="EN-US">Katz's domesti</span><span lang="IN">c product</span><span lang="EN-US"> is not available</span><span lang="EN-US">yet</span><span lang="IN">.</span><span lang="EN-US"> Th</span><span lang="IN">is</span><span lang="EN-US"> research aims to create a laboratory-scale</span><span lang="IN"> modified</span><span lang="EN-US"> Kato</span><span lang="IN">-</span><span lang="EN-US">Katz kit for early detection of</span><span lang="IN"> STHs</span><span lang="IN">infection by fecal egg counts (FECs) in estimating the number of eggs per gram of stool (EPG).</span><span lang="IN">An experimental study was conducted to create a resin template, spatulas, and 3M-adhesive tape as a modified Kato-Katz Kit. 120 </span><span lang="EN-US">Kato-Katz thick smear preparations were done</span><span lang="IN"> from 30 samples for modified and standard Kato-Katz with duplication. The</span><span lang="EN-US"> amount of stool for each</span><span lang="IN"> was weighed. All Kato-Katz thick smear microscopic examination was done at least 60 minutes by identifying the STHs eggs and counting them.</span><span lang="EN-US">The result</span><span lang="IN"> for both methods</span><span lang="EN-US"> showed</span><span lang="IN"> no differences in EPG for <em>Trichuris trichiura </em>eggs p-value=0.012<em> </em>(p&lt;0.05),<em> </em>meanwhile the differences for <em>Ascaris lumbricoides eggs </em>p-value=0.156<em>,</em> and Hookworm eggs p-value=0.102 (p&gt;0.05). Under microscopic examination, some <em>A.lumbricoides </em>eggs morphology was not visible because the adhesive in modified Kato-Katz blurry it, and the Hookworm fragile eggshells made it disappear within less than 60 minutes.</span><span lang="EN-US">The study concluded</span><span lang="IN"> no difference in EPG for <em>T.trichiura </em>eggs by FECs between</span><span lang="IN">modified</span><span lang="EN-US"> Kato-Katz</span><span lang="IN">as this study product with the standard. It is recommended to improve modified Kato-Katz in further study, especially the adhesive tape, before using it as a quantitative tool</span><span lang="IN">for</span><span lang="IN">early </span><span lang="EN-US">detection of </span><span lang="IN">STHs infection.</span><p> </p>