bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in the medical-seeking pattern and daily behavior of hematopoietic stem-cell transplant recipients during the COVID-19 epidemic: An online survey in Hubei Province, China
Authors: Xie Rong , Zhang Yicheng , Huang Zhiping , Cheng Si , Guo Jingming , Zhang Youshan , Liu Min , Zhu Xiaojian , You Yong , Zou Ping , Chen Wenlan , Yan Han , Cheng Fanjun , Zhong Zhaodong 
Published: October 2022

BackgroundTo curb the spread of the coronavirus disease 2019 (COVID-19) epidemic, the Chinese government shut down Wuhan city from January 23rd to April 8th, 2020. The COVID-19 epidemic not only leads to widespread illness but also affects the diagnosis and treatment of hematopoietic stem-cell transplant (HSCT) recipients.ObjectiveTo investigate the medical-seeking pattern and daily behavior changes in Hubei Province during the COVID-19 epidemic in Hubei Province during the lockdown.MethodsWe conducted a multicenter, cross-sectional, web-based investigation among 325 HSCT recipients by online questionnaires in Hubei Province during the COVID-19 epidemic.ResultsA total of 145 complete responses were collected both before and during the epidemic questionnaires. The participants from pre-epidemic group preferred to go to hospital (68.29%) when they experienced influenza-like symptoms. The majority of the patients elected to take oral drugs by themselves (40%) or consulted their attending physicians online or by telephone during the lockdown (23.33%). 64.83% had difficulties in purchasing drugs during the lockdown, which was significantly higher than the proportion of the pre-epidemic group (24.83%) (P &lt; 0.05). The participants preferred to purchase drugs online (23.40%) and decrease or withdraw drugs (18.09%) during the epidemic. The number of participants received regular re-examinations during the epidemic decreased sharply. The proportion of wearing masks and isolating themselves at home increased significantly during the epidemic. No statistic difference was observed in the incidence of graft-versus-host disease (GVHD)complications in participants between the during the epidemic group and the pre-epidemic group. In our study, six patients were confirmed to have COVID-19, and half of them died due to COVID-19-related complications.ConclusionThe medical-seeking pattern and daily behavior of HSCT recipients changed during the lockdown; the methods of self-protection, online consultation and drug delivery can help patients receive necessary follow-up and reduce the occurrence of COVID-19.
Gender specific cut-off points of age for disability among rural elderly in Anhui Province, China
Authors: He Xinran , Wang Xianwen , Zhang Min , Zhu Weizheng , Liu Yuyang , Sun Qian , Chen Guimei , Li Min , Ding Hong 
Published: October 2022

ObjectiveThe purpose of this study was to determine the optimal cut-off values of age for disability in order to predict the risk of disability for older adults in rural areas.MethodsWHO Disability Assessment Schedule 2.0 was used to assess disability. The cut-off values of age for disability were obtained by ROC curve analysis.ResultsThe cut-off points of age for cognition restriction, mobility restriction, self-care restriction, getting along with people restriction, life activities restriction, and social participation restriction for men were 70.5, 68.5, 72.5, 70.5, 71.5, and 68.5 years old, respectively. The cut-off points of age for cognition disability, mobility restriction, self-care disability, getting along with people disability, life activities disability, and social participation disability for women were 72.5, 71.5, 70.5, 70.5, 71.5, and 71.5 years old, respectively. Over the cut-off values of age was an independent risk factor for disability (P &lt; 0.05).ConclusionPresenting first disability symptoms were different between men and women. Preventive efforts to prevent future disability should be different for men and women.
Glycemic control and its influencing factors in type 2 diabetes patients in Anhui, China
Authors: Xing Xiu-Ya , Wang Xin-Yi , Fang Xi , Xu Jing-Qiao , Chen Ye-Ji , Xu Wei , Wang Hua-Dong , Liu Zhi-Rong , Tao Sha-Sha 
Published: October 2022

ObjectiveTo investigate the status of glycemic control and analyze its influencing factors in patients with type 2 diabetes (T2D) in Anhui, China.Methods1,715 T2D patients aged 18–75 years old were selected from 4 counties or districts in Anhui Province in 2018, using a convenience sampling method. All patients have undergone a questionnaire survey, physical examination, and a glycosylated hemoglobin (HbA1c) test. According to the 2022 American Diabetes Association criteria, HbA1c was used to evaluate the glycemic control status of patients, and HbA1c &lt; 7.0% was defined as good glycemic control. The influencing factors of glycemic control were analyzed by multivariate unconditional logistic regression.ResultsThe prevalence of good glycemic control among people with T2D in the Anhui Province was low (22.97%). On univariate analysis, gender, education level, occupation, region, smoking, drinking, waist circumference and disease duration (all P &lt; 0.05) were significantly associated with glycemic control. The factors associated with pool glycemic control were female gender [OR = 0.67, 95%CI (0.52, 0.86), P = 0.001], higher level of education [OR = 0.47, 95%CI (0.27, 0.83), P = 0.001], living in rural areas [OR = 1.77, 95%CI (1.39, 2.26), P &lt; 0.001], central obesity [OR = 1.58, 95%CI (1.19, 2.09), P = 0.001] and longer duration of disease [OR = 2.66, 95%CI (1.91, 3.69), P &lt; 0.001].ConclusionsThe prevalence of good glycemic control in people with T2D in Anhui Province was relatively low, and gender, region, education level, central obesity and course of the disease were influencing factors. The publicity and education on the importance of glycemic control should be further strengthened in T2D patients, and targeted intervention measures should be carried out for risk groups.
COVID-19 vaccination hesitancy and willingness among pregnant women in Italy
Authors: Miraglia del Giudice Grazia , Folcarelli Lucio , Napoli Annalisa , Corea Francesco , Angelillo Italo Francesco ,   The Collaborative Working Group
Published: October 2022

BackgroundPregnant women, especially those with comorbidities, compared to those non-pregnant, have higher risk of developing a severe form of COVID-19. However, COVID-19 vaccine uptake is very low among them.MethodsAn anonymous questionnaire was administered to randomly selected women 18 years of age that were currently pregnant or had just given birth between September 2021 and May 2022 in the geographic area of Naples. Vaccine hesitancy was assessed using the vaccine hesitancy scale (VHS).ResultsA total of 385 women participated. Women who had not been infected by SARS-CoV-2 and who needed information about vaccination against COVID-19 had a higher perceived risk of being infected with SARS-CoV-2. More than half (54.3%) of the women were very afraid of the potential side effects of the COVID-19 vaccination on the fetus. There was higher concern of the side effects of the vaccine on the fetus among those who did not have a graduate degree, those with high-risk pregnancy, those who had not been infected by SARS-CoV-2, those who were more concerned that they could be infected by SARS-CoV-2, those who did not know that this vaccination was recommended for them, and those trusting mass media/internet/social networks for information. Only 21.3% were vaccinated when pregnant, mostly women with a university degree, those who had been infected by SARS-CoV-2 before pregnancy, those who did not need information, and those who acquired information about the vaccination from gynecologists. Almost three-quarters (71.9%) were willing to receive the vaccination and those more likely were those with a university degree, those who have had at least one relative/cohabitant partner/friend who had been infected by SARS-CoV-2, those who were more concerned that they could be infected by SARS-CoV-2, and those who were not extremely concerned of the side effects of the vaccine on the fetus. A total of 86.4% were highly hesitant. Highly hesitant were respondents who did not get a graduate degree, those less concerned that they could be infected by SARS-CoV-2, and those trusting mass media/internet/social networks for information.ConclusionPublic health efforts and education campaigns for pregnant women are needed for changing their perception patterns and for supporting gynecologists in promoting the uptake of this vaccination.
Análisis de la sentencia de unificación del 29 de enero de 2020 de la Sección Tercera del Consejo de Estado que estableció los parámetros de la caducidad en los delitos de lesa humanidad y crímenes de guerra
Authors: Cortés Fajardo María Fernanda , Céspedes Cardona Natalia 
Published: October 2022

En el presente artículo se estudia la sentencia de unificación del 29 de enero de 2020 de la Sección Tercera del Consejo de Estado, en la cual se establecieron los parámetros para el cómputo de la caducidad en el medio de control de reparación directa, cuando el daño es causado por delitos de lesa humanidad y crímenes de guerra cometidos por agentes del Estado, reglas que, como se determinará, desconocen la jurisprudencia de la Corte Interamericana de Derechos Humanos, sentencia Caso Órdenes Guerra y Otros vs. Chile. En el artículo se defenderá que adoptar las reglas jurisprudenciales dispuestas en la sentencia de unificación implica una grave violación al derecho de acceso a la administración de justicia para las víctimas de esta clase de delitos, el desconocimiento del principio pro homine e, inclusive, llegar a configurar una revictimización.
ANALISIS KAPABILITAS PROSES MESIN FILLING UNTUK PENGENDALIAN KUALITAS PADA PRODUK SIRUP OBAT BATUK DI INDUSTRI FARMASI
Authors: Mukhamad Arif  
Published: October 2022

Abstrak
PT ABC adalah salah satu perusahaan swasta milik perseorangan yang bergerak dibidang industri farmasi. Salah satu produk obat yang di produksi adalah sirup obat batuk merk XYZ. Masalah yang terjadi dalam penelitian ini adalah adanya pemborosan produksi disebabkan oleh ketidakstabilan volume produk khususnya produksi sirup obat batuk XYZ. Penelitian ini bertujuan untuk menganalisa nilai kapabilitas proses yang dihasilkan dari mesin filling produksi sirup obat batuk terutama parameter volume dan mengetahui faktor-faktor penyebab terjadinya ketidaksesuaian dalam produk. Beberapa metode yang digunakan dalam penelitian ini antara lain peta kendali, kapabilitas proses dan Fishbone. Hasil penelitian ini menunjukan volume produk obat batuk sirup dari hasil filling sirup dari produksi obat batuk di industri farmasi didapatkan indeks Cp rata-rata sekitar 0.45 dan Cpk rata-rata 0.45. Sehingga dapat disimpulkan bahwa proses belum memiliki kapabilitas yang baik.

Kata Kunci: Sirup obat batuk, proses, Cp, Cpk, Fishbone
POSSIBILITY OF USING EXISTING ELECTRONIC DOCUMENT MANAGEMENT SYSTEMS IN THE PRODUCTION OF SOLID RELAYS
Authors: Трубицын Д.Н. 
Published: October 2022

Рассматриваются функциональные возможности различных существующих систем электронного документооборота и систем автоматизированного проектирования. Перечислены основные функции САПР и СЭД при решении задач в различных подразделениях производства. Для примера рассмотрены СЭД Directum, Microsoft sharepoint и Дело. Из номенклатуры существующих систем автоматизированного проектирования рассмотрены Компас-3D, Altium designer и AutoCAD. Выполнен анализ их функционала, представлены достоинства и недостатки систем при использовании их в проектировании и производстве твердотельных реле. Проанализированы их совместимость между собой и сложности, возникающие при обмене информацией и переводе документов из одной системы в другую. Приводится сравнительная таблица функциональных возможностей современных САПР и СЭД. Рассматриваются варианты решений проблемы передачи данных между различными САПР и СЭД и делается вывод о целесообразности расширения функционала одной из существующих СЭД или САПР для обеспечения взаимосвязи между различными документами проекта, и возможно, в дальнейшем автоматического выпуска отдельных документов при наличии в предыдущих документах всей необходимой информации для формирования нового документа
The article discusses the functionality of various existing electronic document management systems and computer-aided design systems. The main functions of CAD and EDMS, when solving problems, in various departments of production are listed. As examples, EDMS Directum, Microsoft sharepoint and Delo are considered. From the range of existing computer-aided design systems, Compass-3D, Altium designer and AutoCAD are considered. I carried out the analysis of their functionality, advantages and disadvantages of systems, when using them in the design and production of solid relays. I also analyzed their compatibility with each other, and the difficulties that arise when exchanging information and translating documents from one system to another. The article provides a comparative table of the functionality of modern CAD and EDMS. The article also discusses options for solving the problem of data transfer between various CAD and EDMS, and concludes that it is expedient to expand the functionality of one of the existing EDMS or CAD systems to ensure the relationship between various project documents, and possibly, in the future, the automatic release of individual documents, if available in previous documents all the necessary information to form a new document
CALCULATION OF THE RESIDUAL FUNCTION IN THE BASIS SPACE TO SEARCH FOR AREAS OF UNCERTAINTY OF THE RATE CONSTANTS OF THE POLYMERIZATION PROCESS
Authors: Гиззатова Э.Р. , Шагиахметов А.Р. , Хисаметдинова Г.К. , Подвальный С.Л. 
Published: October 2022

Предлагаeтся к рассмотрению математическая модель процесса полимеризации на катализаторах Циглера-Натта, в предположении существования только трех элементарных стадий: роста полимерной цепи, передачи цепи на мономер и передачи цепи на алюминийорганическое соединение при условии отсутствия стадии инициирования активных центров. Приведены постановки прямой и обратной кинетической задач, последняя из которых заключается в поиске областей неопределенных для констант скоростей стадий роста и передач цепи. Показано, что для рассматриваемого процесса значения констант могут быть определены в базисном пространстве, построенном на векторах констант. В отличие от исходного трехмерного пространства базисное пространство позволяет рассчитывать и визуализировать сеточные поверхности по функции невязки для среднечисленной молекулярной массы. При условии расчета невязки как максимума отклонений или суммы квадратов отклонений получают разные поверхности. Показано, как наложение поверхностей друг на друга локализует области минимума, которые впоследствии можно характеризовать как решение обратных кинетических задач. При этом такой подход позволяет оценить форму и вид «овражных» минимумов и, в целом, определять оптимальные наборы констант, идентифицирующие точки минимума
The paper proposes a mathematical model of the polymerization process on Ziegler-Natt catalysts, assuming the existence of only three elementary stages: the growth of the polymer chain, the transfer of the chain to the monomer and the transfer of the chain to the organoaluminium compound, provided there is no stage of initiation of active centers. We give the statements of direct and inverse kinetic problems, the latter of which consists in finding the regions of the chain growth stages and gears that are indeterminate for the rate constants. We show that for the process under consideration, the values of the constants can be determined in the basis space constructed on the vectors of the constants. Unlike the original three-dimensional space, the basis space allows calculating and visualizing grid surfaces by the residual function for the average calculated molecular weight. If the discrepancy is calculated as the maximum of deviations or the sum of the squares of deviations, different surfaces are obtained. We show the way the superposition of surfaces on each other localizes the minimum regions, which can subsequently be characterized as the solution of inverse kinetic problems. At the same time, this approach allows us to evaluate the shape and appearance of "gully" minima and, in general, to determine the optimal set of constants identifying the minimum points
A Educação Estatística: reflexões em contextos formativos no Distrito Federal e em Goiás
Authors: Da Silva Pina Neves Regina , Aparecida de Oliveira Baccarin Sandra , Caldeira Silva Jhone 
Published: October 2022

Nas orientações curriculares nacionais, a estatística se faz presente desde os primeiros anos de escolarização, sendo seu ensino e aprendizagem defendidos de modo a desenvolver a literacia estatística. Este estudo discute a Educação Estatística em contextos de formação inicial de professores de matemática no Distrito Federal e em Goiás, tendo como objetivo investigar a compreensão conceitual de licenciandos em matemática sobre medidas de tendência central. Para tanto, desenvolve-se um estudo qualitativo interpretativo de 151 ingressantes e 68 concluintes em resposta a questões do Exame Nacional do Ensino Médio (Enem). Os resultados evidenciam dificuldades em maior número entre os ingressantes em relação aos conceitos de média, moda e mediana. Tais dificuldades questionam a qualidade das interações conceituais vivenciadas por eles na Educação Básica; impõem limitações na interação desses estudantes com os domínios curriculares próprios do Curso Superior, o que prejudica sua formação, e podem limitar sua futura prática docente.
Peranan PT JPLM pada Skema Relasi Kopi dalam upaya Peningkatan Ekspor Kopi di Bandung Selatan
Authors: Darlin Evalina , Hanarti Inna , Nurdin Nurdin 
Published: October 2022

Berdasarkan data perkembangan ekspor kopi Indonesia ke beberapa negara pada tahun 2015-2019, dapat dilihat bahwa perkembangan ekspor kopi cenderung mengalami penurunan. Untuk itu PT Java Preanger Lestari Mandiri (PT JPLM) mengambil peran dalam mengatasi penurunan ekspor kopi, khususnya di Kabupaten Bandung Selatan. Lingkup penelitian ini meliputi potensi dan bentuk relasi, serta pendampingan terhadap petani kopi Arabika Preanger. Penelitian difokuskan di daerah Kabupaten Bandung Selatan, Jawa Barat. Metode penelitian secara kualitatif dengan teknik pengumpulan datanya triangulasi dan analisis data secara induktif. Tahapan pertama, peneliti melakukan penelitian nilai ekspor kopi Indonesia selama lima tahun terakhir. Kedua, meneliti tentang bentuk skema relasi kopi yang dilakukan oleh PT JPLM. Ketiga, meneliti bentuk dukungan pemasaran dan pengembangan kerja sama penjualan kopi dengan calon pembeli di dalam dan luar negeri. Penelitian ini bertujuan untuk menganalisis bentuk skema relasi kopi yang dilakukan oleh PT JPLM kepada para petani kopi. Melalui penelitian ini maka yang pertama, akan terpaparkan secara jelas dan terperinci mengenai potensi ekspor kopi yang belum teroptimalkan, yang kedua akan terdapat hasil analisis yang jelas mengenai bagaimana bentuk relasi kopi antara PT JPLM dengan para petani kopi dan yang ketiga akan diketahui mengenai dampak relasi kopi terhadap para petani kopi.
Malestar psicológico en pacientes oncológicos durante la pandemia por SARS-CoV2 en un Hospital Minsa - Lambayeque, 2020
Authors: García-Alarcón Liliana Julissa , Horna-Asenjo Diana Margot , Soto-Cáceres Victor , De La Cruz-Mio Jorge Luis 
Published: October 2022

Objetivo: Describir el impacto emocional en pacientes oncológicos durante la pandemia por SARS-COV2. Material y métodos: Estudio observacional, descriptivo, transversal y prospectivo, en un hospital de Lambayeque, Perú 2020, con una muestra de 201 pacientes que se obtuvo usando una proporción esperada del 50 %, un margen de error del 6 % y un nivel de confianza del 95 %. Se utilizó la Escala de Malestar Psicológico de Kressler-10 para evaluar el nivel de malestar de depresión y ansiedad; además de un cuestionario evaluando las características epidemiológicas, clínicas, y de las actitudes del paciente frente a la atención brindada por el establecimiento de salud. Resultados: El 63.68 % de los pacientes presentó malestar emocional. La edad promedio fue de 53,82. En el análisis bivariado se encontró asociación estadísticamente significativa entre presentar malestar y las variables sexo (p<0.05), situación económica (p=0.05) y buena atención sanitaria durante la crisis (p<0.05), Conclusiones: Los pacientes oncológicos presentan una prevalencia de gran importancia de malestar con un punto de corte mayor o igual de 21 puntos en la Escala de Malestar Psicológica de Kessler-10, asociándose algunas características como el ser mujer, el empeoramiento de la situación económica y la propia percepción sobre la atención que le es brindada por el establecimiento de salud, presenten mayor impacto emocional en el contexto de la pandemia.
Palabras clave: neoplasias, depresión, ansiedad, trastornos mentales, pandemia, covid-19. (Fuente: DeCS BIREME)
A Comprehensive Study of Five Intermediate-age Pismis (2, 3, 7, 12, 15) Clusters Using Photometric and Astrometric Data from Gaia EDR3
Authors: Bisht D. , Zhu Qingfeng , Elsanhoury W. H. , Yadav R. K. S. , Rangwal Geeta , Sariya Devesh P. , Durgapal Alok , Jiang Ing-Guey 
Published: October 2022

Abstract
Open clusters are groups of stars that form simultaneously; hence, these are excellent probes to test theories of star formation, stellar evolution, and dynamics in the Milky Way disk. We carry out a detailed photometric and kinematic study of five poorly studied intermediate-age open clusters, Pismis 2 (Pi 2), Pismis 3 (Pi 3), Pismis 7 (Pi 7), Pismis 12 (Pi 12), and Pismis 15 (Pi 15), using the Gaia EDR3 database. By estimating the membership probabilities of stars, we recognized 635, 1488, 535, 368, and 494 most probable members for these clusters by using proper-motion and parallax data taken from Gaia EDR3. The radial density profiles of cluster members provide cluster radii of 4.′5–6.′5 for these clusters. Their ages range from 0.9 to 2.5 Gyr, and distances range, using parallax, from 2.15 to 5.10 kpc. The overall mass function slopes for main-sequence stars are found as 0.27 ± 0.16 (for 1.0–1.6 M
⊙ stars), 0.86 ± 0.27 (for 1.0–2.1 M
⊙ stars), 1.08 ± 0.32 (for 1.0–2.2 M
⊙ stars), 0.89 ± 0.38 (for 1.0–2.2 M
⊙ stars), and 1.07 ± 0.28 (for 1.0–2.1 M
⊙ stars) for clusters Pi 2, Pi 3, Pi 7, Pi 12, and Pi 15. Our obtained values of slopes are flatter in comparison with Salpeter’s value (x = 1.35) within uncertainty. The present study demonstrates that all these Pismis clusters are dynamically relaxed. We found that these objects follow a circular path around the Galactic center. We compute these clusters’ apex coordinates (A, D) and other kinematic parameters.