bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of tobacco cessation activities in the dental settings- A short survey study of 114 responses
Authors: Sonawane Yogashree , Naviwala Gulam , Yadav Omprakash , Sharda Prachi 
Published: December 2022

A questionnaire survey designed for a population study to assess the tobacco cessation activities carried out in a dental setting.1) To assess the approach followed by dental doctors toward tobacco cessation activities in the dental setting. 2) To understand the barriers (if any) faced by the dentists in conducting tobacco cessation activities. To achieve the aforementioned objectives, a cross-sectional research study was designed to gather information on the approach toward tobacco cessation in a dental setting. This questionnaire was further circulated through diverse WhatsApp groups and through posts on social media sites to obtain responses. Although screening for tobacco-related habits in a dental setting is crucial, only around 40% of the survey respondents reported having “always” (5 out of 5 cases) screened for tobacco-related habits. Nearly 49% of the survey respondent, lacked basic tobacco-related IEC material like banners, posters, demonstration videos, or help books required for patient sensitization. About 64% of respondents reported that they had never attended any tobacco cessation workshops while around 85% of respondents were willing to attend tobacco cessation workshops in near future. The article highlights the role of dentists in the screening of tobacco-related habits. It emphasizes the need for improved IEC/BCC activities to curb the tobacco pandemic. Catering to training needs and sensitization of the dental workforce for effective management of tobacco cases is also being pinpointed. The development of exclusive guidelines or templates for screening forms a major crux of the study.
Cyber Teaching dan Ancaman Alienasi: Potret Kecil Keterasingan Mahasiswa di Tengah Pandemi Covid-19
Authors: Zahrawati Fawziah , Andi Aras  
Published: December 2022

Tujuan penelitian ini untuk mengetahui dampak cyber teaching di masa pandemi covid-19, ancaman alienasi yang dialami mahasiswa, dan solusinya. Metode yang digunakan adalah metode kualitatif dengan jenis penelitian fenomenologi. Subjek penelitian ini adalah mahasiswa Tadris IPS Fakultas Tarbiyah IAIN Parepare. Teknik pengumpulan data adalah observasi dan wawancara. Hasil penelitian menunjukkan bahwa cyber teaching menawarkan efisiensi dan keterbukaan akses informasi. Namun tidak lepas dari dampak negatif seperti mahasiswa cenderung berpikir pragmatis, terjadinya degradasi moral, kenakalan, dan tindak menyimpang. Selain itu, di masa pandemi covid-19, mahasiswa menghabiskan banyak waktu di depan layar dunia virtual. Hal ini dapat menjadikan mereka teralienasi. Pemberian tugas yang tidak proporsional dan tepat dapat menggiring mahasiswa ke dalam kondisi keterasingan. Mahasiswa dapat menjadi sosok yang terasing baik pada dirinya sendiri, maupun lingkungannya. Mereka menjadi sosok yang tidak merdeka dan tidak otonom dalam belajar. Oleh karena itu, diperlukan pendidikan yang humanis dengan menjadikan mahasiswa sebagai sosok yang aktif dalam proses belajarnya.
Kata Kunci: alienasi, Covid-19, cyber teaching, pendidikan humanis.
Construyendo salud intercultural en América Latina. Avanzando hacia la equidad
Authors: Del Pino Sandra , Gómez Susana 
Published: December 2022

En América Latina se han venido impulsando importantes esfuerzos para lograr la equidad en salud y hacer frente a las desigualdades que enfrentan los pueblos indígenas de la región. Existen numerosos compromisos internacionales y regionales, incluida la Agenda 2030 para el Desarrollo Sostenible y su lema de “no dejar a nadie atrás”, que sirven como marco de referencia para avanzar hacia la eliminación de las inequidades en salud. Sin embargo, ha sido importante fomentar el reconocimiento por parte de los países de la necesidad de adoptar enfoques diferenciados que contemplen le pertenencia étnica, no solo desde un plano de determinantes sociales de la salud, sino también desde el valor de la cultura, los conocimientos y las tradiciones para avanzar la situación de salud de los pueblos indígenas.
Las desigualdades han quedado aún más visibilizadas con la llegada de la COVID-19 y sus devastadoras consecuencias para los pueblos indígenas, entre otros grupos. A través de los diálogos de saberes, se puede contribuir a los avances en el logro del acceso y de la cobertura universal en salud. Desde la Organización Panamericana de la Salud (OPS) se están promoviendo esfuerzos para implementar esta metodología en el ámbito de la salud y generar mínimos interculturales para avanzar hacia la equidad.
The prevalence and structure of chronic tonsillar pathology in the Samara region
Authors: Vladimirova T. Yu. , Blashentsev M. K. 
Published: December 2022

Purpose: to study the dynamics of the incidence of chronic tonsillitis in the population of the Samara region for 2018-2021.Materials and methods: retrospective analysis of information on the number of diseases registered in patients living in the service area of a medical organization with a first diagnosis based on the data of the annual reporting forms No. 12, No. 14 for 2018–2021.Results. The primary incidence of chronic tonsil disease is highest in children aged 0 to 14 years and tends to increase in primary incidence in 2021. There is a positive trend in the form of a decrease in the number of children with CMD. Compared to 2018, the number of patients with CMD in 2021 decreased by 35%. In all age groups there is a decrease in the prevalence of cases of chronic diseases of the tonsils.Conclusions. CMD occupies the 4th place in the structure of respiratory diseases in the age group from 0 to 14 years, while in other age groups this pathology ranks sixth. The primary incidence of CBM is highest in children (0–14 years old) and adolescents (15–18 years old). The prevalence of CBM is also high in children and adolescents and is almost 9–15 times lower in adults (18–60 years old) and persons over 60 years of age. However, in the group of adults (18–60 years old) the number of patients registered in the dispensary is quite high.
Banco Mundial
Authors: Iijima Mayara Haruka Watanabe , Gonçalves Amanda Melchiotti , Guerra Dhyovana , Zanardini Isaura Monica Souza 
Published: December 2022

Este artigo tem como objetivo apresentar algumas reflexões acerca das perspectivas e orientações para a educação anunciadas por meio do Banco Mundial no contexto da pandemia de COVID-19 e procura responder à questão: em quais pressupostos se baseiam as proposições do Banco Mundial para a educação diante do contexto de pandemia de COVID-19? As considerações aqui apresentadas resultam de uma pesquisa bibliográfica e documental cuja abordagem é qualitativa. Para a análise foram selecionados dois relatórios do Banco Mundial que tratam sobre os impactos da pandemia de COVID-19 na formação de capital humano e sobre a formulação de Políticas Públicas considerando o atual período de crise sanitária. Os relatórios são: COVID-19 No Brasil: Impactos e Respostas de Políticas Públicas (2020) e Agindo agora para proteger o capital humano de nossas crianças (2021). As reflexões, mesmo diante de uma crise sanitária, apontam para a continuidade das proposições da década de 1990, sobre o alívio da pobreza e no qual a educação deve ser a promotora de qualificação, de formação de capital humano flexível para a economia globalmente dependente.
Energy Literacy Profile of Vocational High School Teacher Candidates for Renewable Energy Engineering Expertise Program
Authors: Putri Iis Rahmania , Setiawan Agus , Nasrudin Dindin 
Published: December 2022

<div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><span>This study examines the energy literacy profile of engineering students as vocational high school teacher candidates for renewable energy engineering expertise programs in terms of 3 energy literacy domains: knowledge, attitudes, and behavior. This research uses a quantitative approach with a descriptive-comparative design, conducted on 135 engineering students from 3 study programs at the Indonesian University of Education. The results obtained are that the energy literacy knowledge of engineering students as vocational high school teacher candidates for renewable energy engineering expertise programs is low. Still, their energy literacy attitudes and behaviors are quite good. There was no statistically significant difference in energy literacy between the female and male student groups. In this study, it was known that students from 3 study programs received energy content from different courses. Their energy literacy results were influenced by differences in the range and depth of energy content provided by each study program. The results of this study can be a consideration for universities to develop energy literacy education and learning models and pay attention to the needs, content, and depth of energy content in each study program, especially study programs that are qualified as teachers candidates of vocational high school Renewable Energy Engineering Expertise Program. </span></p></div></div></div>
Effect of QR Code Scan-Based 3D Puzzle Media on Learning Outcomes in Class V Science Learning in Elementary Schools
Authors: Sholicahah Maratus , Setiyawati Enik 
Published: December 2022

This study aims to determine whether there is an effect of scan barcode based 3D Puzzle Media on Learning Outcomes in 5th Grade Students of SDN Krembung 1 Science Learning. This type of research is a quantitative experiment with the type of pre-experimental designs in the form of one-group pretest-posttest design. The instrument in this study uses pretest and posttest test instruments. The samples in this study were grade 5 students at SDN Krembung 1. The results showed that there was an effect of audio-visual-based 3D puzzle media on learning outcomes in science learning which was obtained t count = 2.052, then obtained t table 1729. Because 2,052 > 1,729 Ho is rejected and Ha is accepted, it means that there is a significant difference. From the calculation results of the normlized g > 0.70 test which interprets the high (high) effect of using audio-visual-based 3D puzzle media on learning outcomes in science learning. To find out how much influence scan barcode 3D puzzle media has on learning outcomes in science learning, 5th grade students of SDN Krembung 1 can see in the table n gain score % which interprets the use of puzzle media on learning outcomes in science learning as much as 70.71%.
Monitoring the neural activity associated with praying in Sahaja Yoga Meditation
Authors: Pérez-Díaz Óscar , Barrós-Loscertales Alfonso , Schjoedt Uffe , González-Mora José L. , Rubia Katya , Suero José , Hernández Sergio Elías 
Published: December 2022

Abstract
Sahaja Yoga Meditation draws on many religious traditions and uses a variety of techniques including Christian prayer to reach a state known as thoughtless awareness, or mental silence. Based on previous evidence that Christian prayer activates areas associated with social cognition, e.g., medial prefrontal cortex, temporoparietal junction and precuneus, we hypothesized that praying in Sahaja Yoga Meditation would recruit a similar pattern of activity. Sixteen experienced Sahaja Yoga Meditation practitioners were scanned using task based functional Magnetic Resonance Imaging while performing formalized and improvised forms of praying, associated with the achievement of the meditative state of mental silence, and their equivalent secular tasks. Our results showed the deactivation of bilateral thalamus during both prayers compared to secular conditions and the activation in the medial prefrontal cortex that was reduced by religious and formalized secular speech conditions but increased during improvised secular speech. This suggests that the perception of the surroundings mediated by the thalamus is unemployed during these prayers probably due to the inner concentration established and that improvised speech affects the medial prefrontal cortex differently depending if it is used in religious or secular conditions, which does not happen with formalized speech and may be related to the effects of meditation on psychiatric disorders. Our findings suggest that praying by Sahaja Yoga Meditation practitioners is neurophenomenologically different from the social cognitive attempt of praying within Christian praying practices.
Physicians assessment of the Bavarian drug-expenditure control system: A qualitative study
Authors: Zeschick Nikoletta , Gollnick Julia , Muth Julia , Hörbrand Franziska , Killian Peter , Donner-Banzhoff Norbert , Kühlein Thomas , Sebastião Maria 
Published: December 2022

Abstract
Background In 2014 a new system for drug expenditures, the Wirkstoffvereinbarung (WSV) was implemented in Bavaria. In pre-defined indication groups, cost-effectiveness for the prescription of medications shall be enabled based on the selection, quantity, and the proportion of an individual drug. Ambulatory care physicians receive quarterly trend reports on their prescribing behavior. This study examines physicians’ perceptions of the WSV.
Methods Qualitative interviews (n = 20) and seven focus groups (n = 36) were conducted with ambulatory care physicians (e.g. general practitioners, cardiologists, pneumologists). The methodology followed Qualitative Content Analysis.
Results Physicians generally accepted the necessity of prescribing economically. The majority of them rated the WSV positively and better than the previous system. As improvement, they especially named timely feedback in form of easily understandable trend reports, encouraging self-reflection as well as allowing early control options. Problems perceived were drug discount contracts that were strongly criticized as leading to patients mixing up medications. Some perceived constraints of therapeutic freedom.
Conclusions The WSV was seen as useful to reach the accepted goal of cost control. The restrictions of therapeutic freedom partially perceived might be met by improved information on the reasons why some drugs are rated as less economic than others.
Trial registration number: Main ID: DRKS00019820 (German Register of Clinical Studies and World Health Organization)
Groundwater Potential Zone Mapping Using Arc GIS and Analytical Hierarchy Process (AHP) for the case of Lower Omo-Gibe Watershed, Omo-Gibe Basin, Ethiopia
Authors: Tafese Eyasu 
Published: December 2022

Abstract
The demand for and investigation of groundwater are occasionally increased by the ever-increasing population and abrupt climatic changes. To delineate groundwater potential (GWP) zones in the Lower Omo-Gibe Watershed, Omo-Gibe Basin, Ethiopia, an integrated strategy of remote sensing (RS), geographic information systems (GIS), and multi-criteria decision analysis (MCDA) using analytical hierarchical process (AHP) was used. For this purpose, seven GWP influencing thematic layers comprising lineament density, slope, soil, drainage density, landuse landcover, geology and elevation map were used. Scale values for the classes and thematic layers within them were determined using Satty's AHP and based on expert and literary judgment. The thematic layers have been integrated via their weights/rates using weighted overlay spatial function tool of ArcGIS to provide GWP map. The result shows that GWP map comprises very good (13.79%), good (40.68%), moderate (27.06%) and fair (18.45%) zones.
Two different types of kinetics, where the initial rate increases faster or slower than the reactant concentration, can coexist on bell-shaped kinetic dependencies
Authors: Zhuk P. F. , Karakhim S. O. 
Published: December 2022

Abstract
We have shown the possibility of mathematical analysis of complex biochemical reactions without simplifying assumptions regarding their parameters by investigating the mechanism of adenosine triphosphate (ATP) hydrolysis by the “basal” Mg2+-ATPase in which ATP (substrate), Mg2+ (essential activator) and MgATP (true substrate) compete for binding with the enzyme catalytic site. For this mechanism, we proved, using the quasi-steady state principle by Bodenstein, the existence and uniqueness of a quasi-steady state at any fixed parameters (initial reactant concentrations, positive reaction rate constants). On this basis, the definition of the initial reaction rate v as a function of the initial concentrations of ATP (x1), Mg2+ (x2), ATPase (x3) is given and the dependencies v vs xi are investigated. We proved that at fixed initial concentrations of any two reactants, the kinetic curve v vs xi has a unique maximum point. In different regions of the kinetic curve located before and after the maximum point, the initial rate may vary in different ways: in one region it can change more slowly than the reactant concentration, as in the case of hyperbolic dependencies, and in the other it can change much faster than the reactant concentration, as in the case of sigmoid dependencies, which is typical for regulatory enzymes. This initial rate behaviour causes the existence of four different types of bell-shaped kinetic curves. To quantify the degree of sigmoidity of kinetics, we used derivatives (d ln v)/(d ln xi) which allowed us to estimate the maximal velocity of the initial rate change.
MSC codes: 92C45, 65H10
Association between P2Y12 inhibitor reloading and In-hospital Outcomes for patients with Non-ST-segment Elevation Acute Coronary Syndrome already on Chronic P2Y12 receptor inhibitors therapy in China: Findings From the CCC-ACS (Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome) Project
Authors: Wang Yintang , Geng Yu , Zhang Ou , Xu Qin , Xue Yajun , Zhou Boda , Zhang Ping 
Published: December 2022

Abstract
Background
The association between P2Y12 receptor inhibitors reloading and in-hospital outcomes in non-ST-segment elevation acute coronary syndrome (NSTEACS) patients who were on chronic P2Y12 receptor inhibitors therapy remained underdetermined.
Methods
The Improving Care for Cardiovascular Disease in China–Acute Coronary Syndrome (CCC-ACS project) is a national registry active from November 2014 to December 2019. 4790 NSTEACS patients on chronic P2Y12 receptor inhibitors therapy were included. Cox proportional hazard models, Kaplan–Meier curves, and subgroup analyses were conducted.
Results
The NSTEACS patients who received reloading of P2Y12 receptor inhibitors were younger and had fewer comorbid conditions. The reloading group had a lower risk of major adverse cardiac events (MACE) (0.51% vs. 1.42%, P = 0.007), and all-cause death (0.36% vs. 0.99%, P = 0.028), the risks of myocardial infarction and major bleeding were not significantly different between patients with and without reloading. In survival analysis, a lower cumulative risk of MACE could be identified (Log-rank test, P = 0.007) in reloading group. In the unadjusted Cox model, reloading P2Y12 receptor inhibitors was associated with a decreased risk of MACE (HR, 0.35; 95% CI, 0.16-0.78; [P = 0.010]) and all-cause death (HR, 0.37; 95% CI, 0.14-0.94; [P = 0.036]). Reloading of P2Y12 receptor inhibitors was associated with a decreased risk of MACE in most of the subgroups.
Conclusions
In NSTEACS patients already taking P2Y12 receptor inhibitors, we observed a decreased risk of in-hospital MACEs and all-cause mortality and did not observe an increased risk of major bleeding, with reloading. The differential profile in the two groups might influence this association and further studies are warranted.
Clinical trial registration: https://www.clinicaltrials.gov (Unique identifier: NCT02306616, date of first registration: 03/12/2014).
Circadian clock circuitry deconvolutes colorectal cancer and lung adenocarcinoma heterogeneity in a dynamic time-related framework
Authors: Bianchi Fabrizio , Mazzoccoli Gianluigi , Melocchi Valentina 
Published: December 2022

Abstract
Increasing evidence imputes cancer progression and resistance to therapy to intra-tumor molecular heterogeneity set off by cancer cell plasticity. Re-activation of developmental programs strictly linked to epithelial-to-mesenchymal transition and gaining of stem cells properties are crucial in this setting. Many biological processes involved in cancer onset and progression show rhythmic fluctuations driven by the circadian clock circuitry. Novel cancer patient stratification tools taking into account the temporal dimension of these biological processes are definitely needed. Lung cancer and colorectal cancer (CRC) are the leading causes of cancer death worldwide. Here, we show that the molecular heterogeneity characterizing the two deadliest cancers, colorectal (CRC) and lung adenocarcinoma (LUAD), rather than a merely stochastic event is the readout of specific cancer molecular states which correlate with time-qualified patterns of gene expression. We performed time-course transcriptome analysis of CRC and LUAD cell lines and upon computing circadian genes expression-based correlation matrices we exploited pseudo-time points to infer time-qualified patterns in the transcriptomic analysis of real-world data (RWD) from large cohorts of CRC and LUAD patients. Our temporal classification of CRC and LUAD cohorts was able to effectively render time-specific patterns in cancer phenotype switching determining dynamical distribution of molecular subtypes impacting patient prognosis.
Detection of separatrices and chaotic seas based on orbit amplitudes
Authors: Daquin Jerome , Charalambous Carolina 
Published: December 2022

Abstract
The Maximum Eccentricity Method (MEM, Dvorak et al, 2004) is a standard tool for the analysis of planetary systems and their stability. The method amounts to estimating the maximal stretch of orbits over sampled domains of initial conditions. The present paper leverages on the MEM to introduce a sharp detector of separatrices and chaotic seas. After introducing the MEM analogue for nearly-integrable action-angle Hamiltonians, \ie diameters, we use low-dimensional dynamical systems with multi-resonant modes and junctions, supporting chaotic motions, to recognise the drivers of the diameter metric. Once this is appreciated, we present a second-derivative based index measuring the regularity of this application. This quantity turns to be a sensitive and robust indicator to detect separatrices, resonant webs and chaotic seas. We discuss practical applications of this framework in the context of $N$-body simulations for the planetary case affected by mean-motion resonances, and demonstrate the ability of the index to distinguish minute structures of the phase space, otherwise undetected with the original MEM.