bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strong substitutes: structural properties, and a new algorithm for competitive equilibrium prices
Authors: Baldwin Elizabeth , Bichler Martin , Fichtl Maximilian , Klemperer Paul 
Published: April 2022

AbstractWe show the strong substitutes product-mix auction bidding language provides an intuitive and geometric interpretation of strong substitutes as Minkowski differences between sets that are easy to identify. We prove that competitive equilibrium prices for agents with strong substitutes preferences can be computed by minimizing the difference between two linear programs for the positive and the negative bids with suitably relaxed resource constraints. This also leads to a new algorithm for computing competitive equilibrium prices which is competitive with standard steepest descent algorithms in extensive experiments.
Responding to Covid-19: an analysis of position statements of gerontological societies worldwide
Authors: Emmer De Albuquerque Green Caroline , Scharf Thomas , Kessler Eva-Marie 
Published: April 2022

AbstractThe Covid-19 pandemic, with its adverse implications for older adults, has generated unprecedented public interest in issues around age and ageing globally. We systematically investigated the responses of national gerontological and geriatric societies (NGGS) to emerging challenges during the first wave of the pandemic. Framed within traditional research topics in gerontology, the aim was to identify the spectrum of focal points and positions directed towards governments, policy makers, researchers and society. A comprehensive, two-phased data collection strategy generatedN = 22 position statements of NGGS affiliated to the International Association of Gerontology and Geriatrics. Using Ayalon et al. (J Gerontol Ser B, 2020.https://doi.org/10.1093/geronb/gbaa066) thematic categorisation of gerontological research, we applied quantitative and qualitative content analysis to analyse “calls for action” within the statements. The content of NGGS’ position statements show a high level of agreement on the salient topics during the first wave of the pandemic and reveal shared values such as equality, diversity and inclusion of older adults and the discipline of gerontology to be an applied one with relevance to policy and practice. The results can support future interdisciplinary research in gerontology post Covid-19 based on a vision to contribute to a society of all ages.
mTOR deletion ameliorates CD4 + T cell apoptosis during sepsis by improving autophagosome-lysosome fusion
Authors: Wang Hao , Bai Guangxu , Chen Jianwei , Han Wen , Guo Ran , Cui Na 
Published: April 2022

AbstractAutophagy dysfunction contributes to CD4 + T cell apoptosis during sepsis leading to impairment of adaptive immunity. However, the underlying mechanism is unclear. The mammalian target of rapamycin (mTOR) pathway modulates CD4 + T cell survival during sepsis through mechanisms that are not fully understood. We developed a mouse model of sepsis through cecal ligation and puncture (CLP) to investigate dynamic changes in autophagy in CD4 + T cells. We used T cell specific-mTOR/tuberous sclerosis complex 1 (TSC1)-knockout mice to explore the roles of the mTOR pathway in modulating autophagy during sepsis. We observed reduced fusion of autophagosomes with lysosomes in the CD4 + T cells of CLP mice, which may represent a characteristic feature of autophagy dysfunction. Deletion of mTOR relieved autophagosome-lysosome fusion dysfunction and ameliorated apoptosis of CD4 + T cells in CLP mice, but this rescued phenotype was abolished by treatment with bafilomycin A1, a specific A-L fusion inhibitor. We further explored the underlying molecular mechanism and found that phosphorylation levels of transcription factor EB were significant higher in CLP mice and that expression of A-L fusion protein SNAREs were restricted, both of which were ameliorated by mTOR deletion. Taken together, these results suggest that the mTOR pathway plays a critical role in regulation of CD4 + T-cell apoptosis during sepsis, partly through regulation of A-L fusion-related protein transcription.
The impact of financial deprivation on children’s cybersecurity knowledge & abilities
Authors: Prior Suzanne , Renaud Karen 
Published: April 2022

AbstractOnline users require a working knowledge of password “best practice”, as well as the ability to apply such knowledge. Children increasingly operate as independent agents online, and thus also need to be aware of password “best practice”. To meet this need, the Scottish curriculum for excellence includes lessons about password “best practice”. Hence, all Scottish children ought, theoretically, to have similar levels of password-related knowledge. They ought also, by age 8-9, to be able to apply their knowledge. One factor that could deter password-related knowledge acquisition and skill development is financial deprivation. To gauge its impact, we assessed the knowledge and abilities of Scottish 8-9 year old children, in four primary schools, in areas of varying financial deprivation. We uncovered stark differences in knowledge and password retention. There is a clear need for an extra-curricular intervention programme to teach up-to-date password “best practice” and support in developing the required password management skills. This will reduce their online vulnerabilities, whatever their socio-economic background.
Learning with the interactive whiteboard in the classroom: Its impact on vocabulary acquisition, motivation and the role of foreign language anxiety
Authors: Kühl Tim , Wohninsland Patrizia 
Published: April 2022

AbstractWhen used in a sensible way, Interactive Whiteboards (IWB) are supposed to motivate and engage students in learning in the classroom. Thereby, they might also stimulate students who are usually more restrained, such as more anxious students. However, the body of research on the impact of IWB lessons is rather small. The present study investigated whether a 45-minute lesson with the IWB compared to a conceptual identical 45-minute lesson without the IWB would support learning and motivation within the subject English as a foreign language for German students. Moreover, the study examined whether the 45-minute lesson with the IWB compared to the 45-minute lesson without the IWB would be better able to counteract the detrimental effects of foreign language classroom anxiety (FLCA). One hundred and two eighth graders from two secondary schools in Germany took part in this study and were either taught with the IWB (condition IWB; n = 53) or without the IWB (condition No-IWB; n = 50). Results showed that students in the IWB condition stated to be higher motivated and performed better in a vocabulary test than their counterparts in the No-IWB condition. FLCA was negatively correlated with performance in the vocabulary test. Other than expected, learning with the IWB did not compensate the detrimental effect of FLCA, meaning that learning with the IWB was more beneficial than learning without the IWB irrespective of a student’s FLCA. Implications of the study will be discussed.
Bearing Capacity of Cylindrical Caissons in Cohesive-Frictional Soils Using Axisymmetric Finite Element Limit Analysis
Authors: Keawsawasvong Suraparb , Shiau Jim , Yoonirundorn Kittiphan 
Published: April 2022

AbstractThis paper investigates the use of stability factors for estimating the ultimate bearing pressures on cylindrical caissons in cohesive-frictional soils. Rigorous upper and lower bound limit analyses with finite elements in axisymmetric (AX) condition are used for a series of numerical studies. The bearing capacity factors (Nc0, Nq0 and Nγ0) for a surface circular footing are firstly revisited. This is followed by a study on the effect of caisson’s embedded depth ratio (L/D). A comprehensive set of depth factors (Fcd, Fqd and Fγd) is then reported as a function of caisson’s embedded depth ratio (L/D) and soil internal friction angle (ϕ). The obtained results are compared with published solutions in the literature. Several examples are given to validate the principal of superposition as well as to illustrate on how to use the produced factors to estimate the ultimate bearing pressures on cylindrical caissons in cohesive-frictional soils. The study should be of great interests to practitioners.
A New Social Picture Task to Assess Interpretation Bias related to social fears in adolescents
Authors: Henricks Lisan A. , Lange Wolf-Gero , Luijten Maartje , Becker Eni S. 
Published: April 2022

AbstractThis pre-registered study focused on developing a new social picture task to assess interpretation bias related to social fears in adolescents. Using such a pictorial task may increase ecological validity and readily trigger emotional processes compared to more traditional verbal tasks that are often used. In the picture task, ambiguous social pictures were presented, followed by a positive and negative interpretation. In this study, we examined how the new task relates to an already existing interpretation bias task and how the new pictorial task relates to social fears in adolescents. The sample consisted of 329 adolescents aged 12 to 18 years. Interpretation bias was assessed with the newly developed pictorial task and with more traditional verbal vignettes. Social fears were measured with self-report questionnaires. The results suggest that the pictorial task was able to assess interpretation bias comparable to the verbal vignettes, suggesting appropriate convergent validity. Interpretation bias assessed with the picture task was linked to higher levels of fear of negative evaluation, the core symptom of social anxiety, but not to social anxiety symptoms in general. The verbal task was linked to both social fears and thus still seems the preferred method to investigate interpretation bias related to social fears in adolescents. However, we do believe that with further improvement of the pictorial task, it could be a useful addition to the research field.
Understanding the Contributions of Trait Autism and Anxiety to Extreme Demand Avoidance in the Adult General Population
Authors: White Rhianna , Livingston Lucy A. , Taylor Emily C. , Close Scarlett A. D. , Shah Punit , Callan Mitchell J. 
Published: April 2022

AbstractAutism and anxiety are thought to be related to extreme demand avoidance (EDA), which is characterised by intense avoidance of everyday demands. However, the relative importance of autism and anxiety to EDA has yet to be investigated, and little is known about EDA in adulthood. We conducted two online survey studies (Ns = 267 and 549) with adults in the general population to establish the relative importance of autistic traits and anxiety as predictors of demand avoidance, using dominance analysis. Both autistic traits and anxiety were unique and equally important predictors of demand avoidance. These findings suggest EDA is linked to autism and are consistent with the theory that demand avoidance behaviours are potentially anxiety-driven in adults.
Biotechnological recovery of uranium (VI) from Abu Zeneima spent ore residue using green lixiviant
Authors: Khalafalla Mahmoud S. 
Published: April 2022

AbstractPromising green leaching technique was used by Humic acid (HA) for removing uranium from Abu Zeneima spent residue for environmental safety and cost-effective leaching. The studied residue is outlet from vat leaching process using sulfuric acid leaching of carbonaceous shale ore material with initial uranium assays 185 ppm, which representing a hazardous waste. The overall leaching efficiency assaying 93% of uranium using humic acid leaching at curing temperature 70 °C, 13% HA with S/L ratio of 1/1.5 for 15 day. Kinetic study of leaching process proved diffusion controlling mechanism with activated energy 10.297 kJ/mol. Finally; 98% of uranium was extracted using Amberlite IRA- 400 resin with purity of 97.3%.
Systematic implementation of higher order Whitney forms in methods based on discrete exterior calculus
Authors: Lohi Jonni 
Published: April 2022

AbstractWe present a systematic way to implement higher order Whitney forms in numerical methods based on discrete exterior calculus. Given a simplicial mesh, we first refine the mesh into smaller simplices which can be used to define higher order Whitney forms. Cochains on this refined mesh can then be interpolated using higher order Whitney forms. Hence, when the refined mesh is used with methods based on discrete exterior calculus, the solution can be expressed as a higher order Whitney form. We present algorithms for the three required steps: refining the mesh, solving the coefficients of the interpolant, and evaluating the interpolant at a given point. With our algorithms, the order of the Whitney forms one wishes to use can be given as a parameter so that the same code covers all orders, which is a significant improvement on previous implementations. Our algorithms are applicable with all methods in which the degrees of freedom are integrals over mesh simplices — that is, when the solution is a cochain on a simplicial mesh. They can also be used when one simply wishes to approximate differential forms in finite-dimensional spaces. Numerical examples validate the generality of our algorithms.
Spatial variation of rodenticides and emerging contaminants in blood of raptor nestlings from Germany
Authors: Badry Alexander , Schenke Detlef , Brücher Helmut , Chakarov Nayden , Grünkorn Thomas , Illner Hubertus , Krüger Oliver , Marczak Torsten , Müskens Gerard , Nachtigall Winfried , Zollinger Ronald , Treu Gabriele , Krone Oliver 
Published: April 2022

AbstractWildlife exposures to pest controlling substances have resulted in population declines of many predatory species during the past decades. Many pesticides were subsequently classified as persistent, bioaccumulative, and toxic (PBT) and banned on national or global scales. However, despite their risks for non-target vertebrate wildlife, PBT substances such as anticoagulant rodenticides (ARs) are still permitted for use in Europe and have shown to threaten raptors. Whereas risks of ARs are known, much less information is available on emerging agrochemicals such as currently used PPPs and medicinal products (MPs) in higher trophic level species. We expect that currently used PPPs are relatively mobile (vs. lipophilic) as a consequence of the PBT criteria and thus more likely to be present in aqueous matrices. We therefore analyzed blood of 204 raptor nestlings of three terrestrial (red kite, common buzzard, Montagu’s harrier) and two aquatic species (white-tailed sea eagle, osprey) from Germany. In total, we detected ARs in 22.6% of the red kites and 8.6% of the buzzards, whereas no Montagu’s harriers or aquatic species were exposed prior to sampling. ΣAR concentration tended to be higher in North Rhine-Westphalia (vs. North-Eastern Germany) where population density is higher and intense livestock farming more frequent. Among the 90 targeted and currently used PPPs, we detected six substances from which bromoxynil (14.2%) was most frequent. Especially Montagu’s harrier (31%) and red kites (22.6%) were exposed and concentrations were higher in North Rhine-Westphalia as well. Among seven MPs, we detected ciprofloxacin (3.4%), which indicates that risk mitigation measures may be needed as resistance genes were already detected in wildlife from Germany. Taken together, our study demonstrates that raptors are exposed to various chemicals during an early life stage depending on their sampling location and underpins that red kites are at particular risk for multiple pesticide exposures in Germany.
Terminal value calculation with discontinuous financing and debt categories
Authors: Dierkes Stefan , de Maeyer Imke 
Published: April 2022

AbstractEmpirical analyses indicate that active and passive debt management have limited power to explain the financing behavior of firms. Therefore, discontinuous financing, as a combination of active and passive debt management, might be a more realistic financing strategy. However, the properties of this financing strategy for the steady state have not yet been sufficiently analyzed. For this reason, we investigate analytically terminal value calculation with discontinuous financing and derive adjustment formulas for the period-specific levered cost of equity. Since a single adjustment of the entire debt at the beginning of every planning phase might still not be close to the real financing behavior of firms, we modify discontinuous financing by introducing debt categories, which are adjusted successively and include the maturity of debt. For this new financing strategy, we derive valuation equations and an adjustment formula for the constant cost of equity. Finally, we discuss the relevance and applicability of discontinuous financing with debt categories and its impact on the market value of a firm.
Physical activity estimated by osteogenic potential and energy expenditure has differing associations with bone mass in young adults: the raine study
Authors: Ng Carrie-Anne , Scott David , Sim Marc , Zhu Kun , Siafarikas Aris , Hart Nicolas H. , Tan Jocelyn , Chivers Paola 
Published: April 2022

Abstract

Summary

Ground impacts during physical activity may be important for peak bone mass. We found differences in how energy expenditure and impact scores estimated from a physical activity questionnaire related to bone health in young adults. Using both estimate types can improve our understanding of the skeletal benefits of physical activity.

Purpose
It is unclear whether mechanical loading during physical activity, estimated from physical activity questionnaires which assess metabolic equivalents of task (METs), is associated with skeletal health. This longitudinal study investigated how physical activity loading scores, assessed at ages 17 and 20 years, (a) compares with physical activity measured in METs, and (b) is associated with bone mass at age 20 years.

Methods
A total of 826 participants from the Raine Study Gen2 were assessed for physical activity energy expenditure via the International Physical Activity Questionnaire (IPAQ) at age 17 and 20 years. Loading scores (the product of peak force and application rate) per week were subsequently estimated from the IPAQ. Whole-body and appendicular bone mineral density (BMD) at age 20 years were assessed by dual-energy X-ray absorptiometry.

Results
Bland–Altman minimal detectable difference for physical activity Z-
scores at age 17 and 20 years were 1.59 standard deviations (SDs) and 1.33 SDs, respectively, greater than the a priori minimal clinically important change of 0.5 SDs. Loading score, but not IPAQ score, had significant positive associations with whole-body and leg BMD after adjustment for covariates (β = 0.008 and 0.012 g/cm2, respectively, for age 17 and 20 years loading scores). IPAQ score at age 20 years, but not loading score, had a significant positive association with arm BMD (β = 0.007 g/cm2).

Conclusion
This study revealed disagreement in associations of self-reported METs and loading score estimates with bone health in young adults. Coupling traditional energy expenditure questionnaire outcomes with bone-loading estimates may improve understanding of the location-specific skeletal benefits of physical activity in young adults.
Robust Metal Additive Manufacturing Process Selection and Development for Aerospace Components
Authors: Gradl Paul , Tinker Darren C. , Park Alison , Mireles Omar R. , Garcia Marissa , Wilkerson Ryan , Mckinney Christopher 
Published: April 2022

AbstractMetal additive manufacturing (AM) encapsulates the myriad of manufacturing processes available to meet industrial needs. Determining which of these AM processes is best for a specific aerospace application can be overwhelming. Based on the application, each of these AM processes has advantages and challenges. The most common metal AM methods in use include Powder Bed Fusion, Directed Energy Deposition, and various solid-state processes. Within each of these processes, there are different energy sources and feedstock requirements. Component requirements heavily affect the process determination, despite existing literature on these AM processes (often inclusive of input parameters and material properties). This article provides an overview of the considerations taken for metal AM process selection for aerospace components based on various attributes. These attributes include geometric considerations, metallurgical characteristics and properties, cost basis, post-processing, and industrialization supply chain maturity. To provide information for trade studies and selection, data on these attributes were compiled through literature reviews, internal NASA studies, as well as academic and industry partner studies and data. These studies include multiple AM components and sample build experiments to evaluate (1) material and geometric variations and constraints within the processes, (2) alloy characterization and mechanical testing, (3) pathfinder component development and hot-fire evaluations, and (4) qualification approaches. This article summarizes these results and is meant to introduce various considerations when designing a metal AM component.
The Phase Transformation of Silicon Assessed by an Unloading Contact Pressure Approach
Authors: Schaffar Gerald J. K. , Kappacher Johann , Tscharnuter Daniel , Maier-Kiener Verena 
Published: April 2022

AbstractSilicon is of great economic importance for the semiconductor industry as well as of academic interest because of its high-pressure phase transformations. These transformations also occur during the indentation of silicon. To further investigate these transformations, a modified method using the continuous stiffness measurement (CSM) during unloading is presented in this work. The use of the CSM signal allows directly calculating the mean contact pressure while unloading. The measurements will be compared to conventional indentation tests and data from high-pressure cell experiments reported in the literature. Furthermore, the influence of constant load holding segments on the phase transformation during unloading is investigated.
Hand hygiene practices for prevention of health care-associated infections associated with admitted infectious patients in the emergency department: a systematic review
Authors: Issa M , Dunne SS , Dunne CP 
Published: April 2022

Abstract
Background
In most high-income countries, emergency departments (ED) represent the principal point of access forcer by critically ill or injured patients. Unlike inpatient units, ED healthcare workers (ED HCWs) have demonstrated relative lack of adherence to hand hygiene (HH) guidelines, commonly citing frequency of intervention and high rates of admission, which reflect severity of cases encountered.

Aim
Assessment of studies on hand hygiene compliance (HHC) by ED HCWs conducted between 2010 and 2020, seeking to estimate HHC rates and intervention strategies utilised to improve HHC in EDs.

Methods
Searches conducted in Web of Science, EBSCO HOST (CINHAL & Medline), PubMed, Embase, and Cochrane for full studies published between 2010 and 2020 on the topic of HHC in the ED.

Results
One hundred twenty-nine eligible articles were identified of which 79 were excluded. Fifty-one underwent full-text screening before 20 studies were deemed relevant. Of the eligible studies, fifteen (75%) had, as the primary outcome, HHC according to the WHO-recommended 5-moments. Twelve studies (60%) implemented multimodal or single intervention strategies. Eight studies were ambiguous regarding the nature of the approach adopted. In the nine observational studies where HHC was documented, an overall post-intervention median HHC rate of 45% (range 8–89.7%).

Conclusion
Multimodal approaches appear to have enhanced HHC moderately among ED HCWs. Elevated complexity associated with critically ill patients, and ED overcrowding, are contributing factors to relatively low compliance rates observed. Strategies to improve HHC rates may need to acknowledge, and cater for, the context of an unpredictable environment.