bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wired to seek, comment and share? Examining the relationship between personality, news consumption and misinformation engagement
Authors: Xiao Xizhu , Su Yan 
Published: January 2022

PurposeNews consumption is critical in creating informed citizenry; however, in the current context of media convergence, news consumption becomes more complex as social media becomes a primary news source rather than news media. The current study seeks to answer three questions: why the shifted pattern of news seeking only happens to some but not all of the news consumers; whether the differentiated patterns of news seeking (news media vs social media) would result in different misinformation engagement behaviors; and whether misperceptions would moderate the relationship between news consumption and misinformation engagement.Design/methodology/approachA survey consisted of questions related to personality traits, news seeking, misperceptions and misinformation engagement was distributed to 551 individuals. Multiple standard regression and PROCESS Macro model 1 were used to examine the intricate relationships between personality, news use and misinformation engagement.FindingsResults indicate that extroversion was positively associated with social media news consumption while openness was inversely related to it. Social media news consumption in turn positively predicted greater misinformation sharing and commenting. No association was found between Big Five personality traits and news media news seeking. News media news seeking predicted higher intention to reply to misinformation. Both relationships were further moderated by misperceptions that individuals with greater misperceptions were more likely to engage with misinformation.Originality/valueThe current study integrates personality traits, news consumption and misperceptions in understanding misinformation engagement behaviors. Findings suggest that news consumption via news media in the digital era merits in-depth examinations as it may associate with more complex background factors and also incur misinformation engagement. Social media news consumption deserves continuous scholarly attention. Specifically, extra attention should be devoted to extrovert and pragmatic individuals in future research and interventions. People with these characteristics are more prone to consume news on social media and at greater risk of falling prey to misinformation and becoming a driving force for misinformation distribution.Peer reviewThe peer review history for this article is available at: https://publons.com/publon/10.1108/OIR-10-2021-0520
Internationalisation strategies of emerging market firms: evidence from Sarawak, Malaysia
Authors: Amoah Yaa Serwaa-Akoto , Tiew Fidella Nga Huong , Yap Ching Seng 
Published: January 2022

PurposeThis study aims to explore the internationalisation paths and strategies adopted by firms from an emerging market and serves as a step towards examining the suitability of prevailing internationalisation theories in the context of emerging market firms.Design/methodology/approachThis study adopted a qualitative methodology and gathered data through in-depth semi-structured interviews with 15 top managers of internationalised firms from the East Malaysian state of Sarawak. Data were analysed thematically.FindingsThe results revealed that the internationalisation strategies of firms from Sarawak can be classified under three main categories: motivations and markets, modes and measures. The constraints the firms faced were important determinants of their internationalisation strategies. The internationalisation paths and strategies of the firms were also found to exhibit both similarities to and deviations from the tenets of prevailing internationalisation theories.Originality/valueThe study contributes knowledge to the literature of both internationalisation theories and internationalisation strategies of emerging markets, in particular, it advances Feyet al.’s(2016) Five M Framework.
Examination of aspects of pro-consumer refund system
Authors: Lysenko-Ryba Kateryna , Zimon Dominik , Madzík Peter , Šírová Eva 
Published: January 2022

PurposePro-consumer refund system (PCRS) should be understood as a process in customer service, within which activities are related to the handling of goods that do not meet customer expectations, both in business-to-consumer (B2C) and business-to-business (B2B) relations. The research monitored three groups of variables – the importance of shopping decision factors, customer ID characteristics and PCRS characteristics. The authors explore relationships between these three groups of variables, and the authors tried to understand better the role of the PCRS system in customer perception of service quality.Design/methodology/approachAn electronic survey was used to collect data in the planned structure. Research questions were developed into variables, and these were then the basis for creating questionnaires. Data were collected through electronic questionnaires. The sample consisted of 327 respondents from Poland (confidence level = 95%, confidence interval = 5.42).FindingsThe results of the research show that the PCRS is very important and appreciated from the customer's perspective. Most of the respondents are aware of their consumer rights and correctly understand the meaning of the term “pro-consumer refund system”. Respondents require complex service in terms of returns; their satisfaction does not depend on any individual factor. This also means that the return system must be lenient in each aspect.Originality/valueA detailed analysis of aspects of PCRS has not yet been carried out in the literature. Although previous studies have focused, at least in part, on defining the essential attributes of PCRS, in most cases, it was an organization-driven view of this topic. The research examined the interrelationships between aspects of PCRS based on empirical data and offered a new perspective on this evolving concept.
The Scottish National Party’s Economic Prospectus for Independence: Out with the Old?
Authors: Roy Graeme 
Published: January 2022

AbstractNicola Sturgeon has promised to restart work on the prospectus for independence. The economic arguments will once again be central. The fact that the macroeconomic, constitutional and political context has changed markedly since 2014 offers the SNP an opportunity to reset its pitch to the people of Scotland. But, it faces huge challenges in doing so, particularly within the timescale the First Minister has set for a second referendum. Some of these challenges reflect a weaker economic outlook than seven years ago. But, holding together a more diverse Yes campaign on key issues such as currency is arguably an even greater challenge. In refreshing its vision of independence, the SNP can take a more far‐sighted approach than is possible in most elections. If it can complement this with a credible—albeit tough—transition plan, it not only stands a better chance of winning, but will force unionists to re‐think their own strategy.
Lower price increases, the bounded rationality of bidders, and underbidding concerns in online agricultural land auctions: The Ukrainian case
Authors: Myrna Olena 
Published: January 2022

AbstractAuction theory suggests that bidders follow a dominant strategy that is to submit the highest bid equal to the bidder's true valuation in an ascending price auction with independent and private values. Bidders in real‐world auctions may deviate from this strategy, resulting in either underbidding—submitting bids lower than the valuation—or overbidding—bidding an amount in excess of the real value. This study utilises data collected from online agricultural land lease auctions in Ukraine that took place between October 2018 and September 2019 to analyse the occurrence of minimal price increases, which may indicate underbidding. It investigates if factors—auction and property characteristics—that typically explain deviations from the dominant strategy—can also explain bidding behaviours in land lease auctions. The estimation using a heteroscedastic probit model reveals that underbidding could reasonably be attributed to low competition, insufficient time to place a subsequent bid, very small bid increments, and cumbersome entry fees.
The dark side of social media: Two deaths related with chloroform intoxication
Authors: Tusiewicz Kaja , Wachełko Olga , Zawadzki Marcin , Chłopaś‐Konowałek Agnieszka , Jurek Tomasz , Kawecki Jerzy , Szpot Paweł 
Published: January 2022

AbstractA suicide pact is an agreement between people to commit suicide together, which usually takes place at the same time, in the same place, by using the same method. Social media serve as a way of communication between people. Thus, they use such platforms to find potential suicide pact partners. Chloroform, although being regarded to as a slightly forgotten poison, is still linked to homicide and suicide cases. Death due to an acute chloroform ingestion may be a result of central nervous system depression. In this paper, we present application of headspace gas chromatographic method using a dual column/dual flame ionization detector (HS‐GC‐FID/FID) for the determination of chloroform in two fatal intoxication cases, as well as chloroform stability study. Analysis of biological samples revealed chloroform concentrations of 135.8, 16.1, 8.1, and 37.1 µg/ml in blood, urine, vitreous humor, and bile, respectively. Kidney, liver, and muscle specimens contained 119.5, 99.6, and 28.4 µg/g of chloroform, respectively. The results of stability studies indicate the highest decrease of chloroform in room temperature, so it is advised to store samples in a freezer. The addition of sodium fluoride is recommended as in blood samples collected to the test tubes without any preservative agent, the detection of chloroform after 91 days is almost impossible. It is important to emphasize that even old poisons can cause a lot of concerns today, as here described cases are linked to chloroform intoxication, as well as with possible danger which social media bring about nowadays.
A new modified internal fixation method of transconjunctival lower blepharoplasty
Authors: Ou Kuangwen , Huang Wenchi , Chin Sokheng 
Published: January 2022

AbstractIn transconjunctival lower eyelid blepharoplasty with pedicled fat transposition, internal fixation of the septal fat is always the most difficult step. We describe a new modified method that makes this procedure less time‐consuming and specific instruments unnecessary.
Development of a deep learning‐based method to diagnose pulmonary ground‐glass nodules by sequential computed tomography imaging
Authors: Qiu Zhixin , Wu Qingxia , Wang Shuo , Chen Zhixia , Lin Feng , Zhou Yuyan , Jin Jing , Xian Jinghong , Tian Jie , Li Weimin 
Published: January 2022

AbstractBackgroundEarly identification of the malignant propensity of pulmonary ground‐glass nodules (GGNs) can relieve the pressure from tracking lesions and personalized treatment adaptation. The purpose of this study was to develop a deep learning‐based method using sequential computed tomography (CT) imaging for diagnosing pulmonary GGNs.MethodsThis diagnostic study retrospectively enrolled 762 patients with GGNs from West China Hospital of Sichuan University between July 2009 and March 2019. All patients underwent surgical resection and at least two consecutive time‐point CT scans. We developed a deep learning‐based method to identify GGNs using sequential CT imaging on a training set consisting of 1524 CT sections from 508 patients and then evaluated 256 patients in the testing set. Afterwards, an observer study was conducted to compare the diagnostic performance between the deep learning model and two trained radiologists in the testing set. We further performed stratified analysis to further relieve the impact of histological types, nodule size, time interval between two CTs, and the component of GGNs. Receiver operating characteristic (ROC) analysis was used to assess the performance of all models.ResultsThe deep learning model that used integrated DL‐features from initial and follow‐up CT images yielded the best diagnostic performance, with an area under the curve of 0.841. The observer study showed that the accuracies for the deep learning model, junior radiologist, and senior radiologist were 77.17%, 66.89%, and 77.03%, respectively. Stratified analyses showed that the deep learning model and radiologists exhibited higher performance in the subgroup of nodule sizes larger than 10 mm. With a longer time interval between two CTs, the deep learning model yielded higher diagnostic accuracy, but no general rules were yielded for radiologists. Different densities of components did not affect the performance of the deep learning model. In contrast, the radiologists were affected by the nodule component.ConclusionsDeep learning can achieve diagnostic performance on par with or better than radiologists in identifying pulmonary GGNs.
Resistance to Lymantria dispar larvae in transgenic poplar plants expressing CYP6B53 double‐stranded RNA
Authors: Sun Lili , Gao Yuan , Zhang Qihui , Lv Yuntong , Cao Chuanwang 
Published: January 2022

AbstractRNA interference (RNAi) has great potential in functional genomics research and pest control. Gene silencing and phenotypes ranging from appetite loss to death have been observed after larvae fed on leaves of double‐stranded RNA (dsRNA)‐expressing transgenic plants harbouring specific genes from the target insect. In this study, transgenic poplar plants expressing CYP6B53 dsRNA from Lymantria dispar were generated via Agrobacterium‐mediated transformation to control this pest. The CYP6B53 was successfully integrated into the poplar genome by reverse transcription PCR (RT‐PCR) and dsCYP6B53 expression confirmation. Expression was significantly down‐regulated at the transcription level after L. dispar larvae feeding on leaves of the transgenic plants. Meanwhile, CYP6B53 transcription levels in the larvae decreased by 25.31–88.53% compared with those reared on transgenic poplar expressing green fluorescent protein (GFP) dsRNA. A bioassay further revealed that transgenic plants expressing dsCYP6B53 not only inhibited larval feeding but also delayed overall growth. In summary, Poplar plants harbouring CYP6B53 dsRNA resulted in suppression of CYP6B53 expression in L. dispar larvae, impairing development, and providing a novel alternative for pest control.
Insight into the content of and experiences with follow‐up conversations with bereaved parents in paediatrics: A systematic review
Authors: van Kempen Merel M. , Kochen Eline M. , Kars Marijke C. 
Published: January 2022

AbstractAimA follow‐up conversation with bereaved parents is a relatively well‐established intervention in paediatric clinical practice. Yet, the content and value of these conversations remain unclear. This review aims to provide insight into the content of follow‐up conversations between bereaved parents and regular healthcare professionals (HCPs) in paediatrics and how parents and HCPs experience these conversations.MethodsSystematic literature review using the methods PALETTE and PRISMA. The search was conducted in PubMed and CINAHL on 3 February 2021. The results were extracted and integrated using thematic analysis.ResultsTen articles were included. This review revealed that follow‐up conversations are built around three key elements: (1) gaining information, (2) receiving emotional support and (3) facilitating parents to provide feedback. In addition, this review showed that the vast majority of parents and HCPs experienced follow‐up conversations as meaningful and beneficial for several reasons.ConclusionAn understanding of what parents and HCPs value in follow‐up conversations aids HCPs in conducting follow‐up conversations and improves care for bereaved parents by enhancing the HCPs' understanding of parental needs.
No party no joy?—Changes in university students' extraversion, neuroticism, and subjective well‐being during two COVID‐19 lockdowns
Authors: Krautter Kai , Friese Malte , Hart Alexander , Reis Dorota 
Published: January 2022

AbstractThe COVID‐19 lockdowns represent a major life event with an immense impact on university students' lives. Findings prior to the pandemic suggest that changes in personality and subjective well‐being (SWB) can occur after critical life events or psychological interventions. The present study examined how university students' extraversion, neuroticism, and SWB changed during two COVID‐19 lockdowns in Germany. To this end, we conducted a partly preregistered, two‐cohort study with four measurement points each from October 2019 to May 2021 (NStudy 1 = 81–148, NStudy 2 = 82–97). We used both multilevel contrast analyses and multi‐group random‐intercept cross‐lagged panel models to examine within‐person changes over time. Levels of life satisfaction, extraversion, and, unexpectedly, neuroticism were lower during both lockdowns. Students' affect improved during the first but deteriorated during the second lockdown, suggesting that similar experiences with the deceleration of daily life were associated with different affective outcomes during the two lockdown periods. Following the introduction or termination of a lockdown, changes in extraversion (neuroticism) were consistently positively (negatively) associated with changes in SWB. Our results stress the importance of disentangling between‐ and within‐person processes and using pre‐COVID baseline levels to examine changes in personality and SWB.
Newborn DNA methylation and asthma acquisition across adolescence and early adulthood
Authors: Li Liang , Holloway John W. , Ewart Susan , Arshad Syed Hasan , Relton Caroline L. , Karmaus Wilfried , Zhang Hongmei 
Published: January 2022

AbstractBackgroundLittle is known about the association of newborn DNA methylation (DNAm) with asthma acquisition across adolescence and early adult life.ObjectiveWe aim to identify epigenetic biomarkers in newborns for asthma acquisition during adolescence or young adulthood.MethodsThe Isle of Wight Birth Cohort (IOWBC) (n = 1456) data at ages 10, 18 and 26 years were assessed. To screen cytosine‐phosphate‐guanine site (CpGs) potentially associated with asthma acquisition, at the genome scale, we examined differentially methylated regions (DMR) using dmrff R package and individual CpG sites using linear regression on such associations. For CpGs that passed screening, we examined their enrichment in biological pathways using their mapping genes and tested their associations with asthma acquisitions using logistic regressions. Findings in IOWBC were tested in an independent cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC) cohort.ResultsIn total, 2636 unique CpGs passed screening, based on which we identified one biological pathway linked to asthma acquisition during adolescence in females (FDR adjusted p‐value = .003 in IOWBC). Via logistic regressions, for females, four CpGs were shown to be associated with asthma acquisition during adolescence, and another four CpGs with asthma acquisition in young adulthood (FDR adjusted p‐value < .05 in IOWBC) and these eight CpGs were replicated in ALSPAC (all p‐values < .05). DNAm at all the identified CpGs was shown to be temporally consistent, and at six of the CpGs was associated with expressions of adjacent or mapping genes in females (all p‐values < .05). For males, 622 CpGs were identified in IOWBC (FDR = 0.01), but these were not tested in ALSPAC due to small sample sizes.Conclusion and clinical relevanceEight CpGs on LHX5, IL22RA2, SOX11, CBX4, ACPT, CFAP46, MUC4, and ATP1B2 genes have the potential to serve as candidate epigenetic biomarkers in newborns for asthma acquisition in females during adolescence or young adulthood.
Cannabinoid WIN55212‐2 impairs peanut‐allergic sensitization and promotes the generation of allergen‐specific regulatory T cells
Authors: Angelina Alba , Jiménez‐Saiz Rodrigo , Pérez‐Diego Mario , Maldonado Angel , Rückert Beate , Akdis Mübeccel , Martín‐Fontecha Mar , Akdis Cezmi A. , Palomares Oscar 
Published: January 2022

AbstractBackgroundCannabinoids are lipid‐derived mediators with anti‐inflammatory properties in different diseases. WIN55212‐2, a non‐selective synthetic cannabinoid, reduces immediate anaphylactic reactions in a mouse model of peanut allergy, but its capacity to prevent peanut‐allergic sensitization and the underlying mechanisms remains largely unknown.ObjectiveTo investigate the capacity of WIN55212‐2 to immunomodulate peanut‐stimulated human dendritic cells (DCs) and peanut‐allergic sensitization in mice.MethodsSurface markers and cytokines were quantified by flow cytometry, ELISA and qPCR in human monocyte‐derived DCs (hmoDCs) and T‐cell cocultures after stimulation with peanut alone or in the presence of WIN55212‐2. Mice were epicutaneously sensitized with peanut alone or peanut/WIN55212‐2. After peanut challenge, drop in body temperature, haematocrit, clinical symptoms, peanut‐specific antibodies in serum and FOXP3+ regulatory (Treg) cells in spleen and lymph nodes were quantified. Splenocytes were stimulated in vitro with peanut to analyse allergen‐specific T‐cell responses.ResultsWIN55212‐2 reduced peanut‐induced hmoDC activation and promoted the generation of CD4+CD127−CD25+FOXP3+ Treg cells, while reducing the induction of IL‐5‐producing T cells. In vivo, WIN55212‐2 impaired the peanut‐induced migration of DCs to lymph nodes and their maturation. WIN55212‐2 significantly reduced the induction of peanut‐specific IgE and IgG1 antibodies in serum during epicutaneous peanut sensitization, reduced the clinical symptoms score upon peanut challenge and promoted the generation of allergen‐specific FOXP3+ Treg cells.ConclusionsThe synthetic cannabinoid WIN55212‐2 interferes with peanut sensitization and promotes tolerogenic responses, which might well pave the way for the development of novel prophylactic and therapeutic strategies for peanut allergy.
The impact of adherence and therapy regimens on quality of life in patients with congenital adrenal hyperplasia
Authors: Ekbom Kerstin , Strandqvist Anna , Lajic Svetlana , Hirschberg Angelica , Falhammar Henrik , Nordenström Anna 
Published: January 2022

AbstractObjectiveVarying outcomes regarding the quality of life (QoL) have been reported in patients with congenital adrenal hyperplasia (CAH). To assess the impact of adherence rate to medical therapy regimens on QoL in patients with CAH.PatientsAdolescents and adults aged 15–72 years with CAH due to 21‐hydroxylase deficiency at Karolinska University Hospital, Stockholm, Sweden.MeasurementsQoL was assessed using the Addison QoL (n = 72) and RAND 36 questionnaires (n = 75). Adherence to therapy regimens was measured using the Adherence Starts with Knowledge questionnaire (ASK‐12). Associations between QoL, type of glucocorticoid therapy prescribed and ASK‐12 results were examined. Results were compared to reference RAND 36 data obtained from a representative sample from the general Swedish population.ResultsA good adherence rate to therapy regimens and a younger age were key factors for a better QoL in study participants with CAH. Younger patients on hydrocortisone and with good adherence had higher RAND 36 scores than older patients on prednisolone independently adherence. Participants with classic CAH (both the salt‐wasting and simple virilizing form) reported higher QoL than those with nonclassic CAH. Patients with CAH, especially nonclassic, more frequently reported an impaired QoL than the general population, especially regarding limitations related to body pain, vitality and mental health.ConclusionA poor adherence rate to therapy regimens, rather than type of glucocorticoid was associated with impaired QoL in adolescents and adults with CAH.