bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic Role of Repetitive Transcranial Magnetic Stimulation in Alzheimer’s and Parkinson’s Disease: Electroencephalography Microstate Correlates
Authors: Hanoglu Lutfu , Toplutas Eren , Saricaoglu Mevhibe , Velioglu Halil Aziz , Yildiz Sultan , Yulug Burak 
Published: February 2022

IntroductionThe microstate analysis is a method to convert the electrical potentials on the multi-channel electrode array to topographical electroencephalography (EEG) data. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive method that can modulate brain networks. This study explores the pathophysiological changes through microstate analysis in two different neurodegenerative diseases, Alzheimer’s (AD) and Parkinson’s disease (PD), characterized by motor and cognitive symptoms and analysis the effect of rTMS on the impaired cognitive and motor functions.Materials and MethodsWe included 18 AD, 8 PD patients, and 13 age-matched controls. For both groups, we applied 5 Hz rTMS on the left pre-SMA in PD patients while 20 Hz rTMS on the left lateral parietal region in AD patients. Each patient was re-evaluated 1 week after the end of the sessions, which included a detailed clinical evaluation and measurement of EEG microstates.ResultsAt the baseline, the common findings between our AD and PD patients were altered microstate (MS) B, MS D durations and transition frequencies between MS A–MS B, MS C–MS D while global explained variance (GEV) ratio and the extent and frequency of occurrence of MS A, MS B, and MS D were separately altered in AD patients. Although no specific microstate parameter adequately differentiated between AD and PD patients, we observed significant changes in MS B and MS D parameters in PD patients. Further, we observed that Mini-Mental State Examination (MMSE) performances were associated with the transition frequencies between MS A–MS B and MS C–MS D and GEV ratio. After left parietal rTMS application, we have observed significantly increased visual memory recognition and clock drawing scores after left parietal rTMS application associated with improved microstate conditions prominent, especially in the mean duration of MS C in AD patients. Also, pre-SMA rTMS resulted in significant improvement in motor scores and frequency of transitions from MS D to MS C in PD patients.ConclusionThis study shows that PD and AD can cause different and similar microstate changes that can be modulated through rTMS, suggesting the role of MS parameters and rTMS as a possible combination in monitoring the treatment effect in neurodegenerative diseases.
Evaluation of Ultrasound Elastography Combined With Chi-Square Automatic Interactive Detector in Reducing Unnecessary Fine-Needle Aspiration on TIRADS 4 Thyroid Nodules
Authors: Liu Xiao , Xie Li , Ye Xianjun , Cui Yayun , He Nianan , Hu Lei 
Published: February 2022

BackgroundConventional ultrasound diagnosis of thyroid nodules (TNs) had a high false-positive rate, resulting in many unnecessary fine-needle aspirations (FNAs).ObjectiveThis study aimed to establish a simple algorithm to reduce unnecessary FNA on TIRADS 4 TNs using different quantitative parameters of ultrasonic elasticity and chi-square automatic interactive detector (CHAID) method.MethodsFrom January 2020 to May 2021, 432 TNs were included in the study, which were confirmed by FNA or surgical pathology. Each TN was examined using conventional ultrasound, sound touch elastography, and Shell measurement function. The quantitative parameters E and Eshell were recorded, and the Eshell/E values were calculated for each TN. The diagnostic performance of the quantitative parameters was evaluated using the receiver operating characteristic curves. The CHAID was used to classify and analyze the quantitative parameters, and the prediction model was established.ResultsA total of 226 TNs were malignant and 206 were benign. Eshell and Eshell/E ratio were included in the classification algorithm, which showed a depth of two ramifications (Eshell/E ≤ 0.988 or 0.988–1.043 or &gt;1.043; if Eshell/E ≤ 0.988, then Eshell ≤ 64.0 or 64.0–74.0 or &gt;74.0; if Eshell/E = 0.988–1.043, then Eshell ≤ 66.0 or &gt; 66.0; if Eshell/E &gt;1.043, then Eshell ≤ 69.0 or &gt;69.0). The unnecessary FNAs could have been avoided in 57.3% of the cases using this algorithm.ConclusionThe prediction model using quantitative parameters had high diagnostic performance; it could quickly distinguish benign lesions and avoid subjective influence to some extent.
Circulating Tumor Cell Identification Based on Deep Learning
Authors: Guo Zhifeng , Lin Xiaoxi , Hui Yan , Wang Jingchun , Zhang Qiuli , Kong Fanlong 
Published: February 2022

As a major reason for tumor metastasis, circulating tumor cell (CTC) is one of the critical biomarkers for cancer diagnosis and prognosis. On the one hand, CTC count is closely related to the prognosis of tumor patients; on the other hand, as a simple blood test with the advantages of safety, low cost and repeatability, CTC test has an important reference value in determining clinical results and studying the mechanism of drug resistance. However, the determination of CTC usually requires a big effort from pathologist and is also error-prone due to inexperience and fatigue. In this study, we developed a novel convolutional neural network (CNN) method to automatically detect CTCs in patients’ peripheral blood based on immunofluorescence in situ hybridization (imFISH) images. We collected the peripheral blood of 776 patients from Chifeng Municipal Hospital in China, and then used Cyttel to delete leukocytes and enrich CTCs. CTCs were identified by imFISH with CD45+, DAPI+ immunofluorescence staining and chromosome 8 centromeric probe (CEP8+). The sensitivity and specificity based on traditional CNN prediction were 95.3% and 91.7% respectively, and the sensitivity and specificity based on transfer learning were 97.2% and 94.0% respectively. The traditional CNN model and transfer learning method introduced in this paper can detect CTCs with high sensitivity, which has a certain clinical reference value for judging prognosis and diagnosing metastasis.
The Effect of International Travel Arrivals on the New HIV Infections in 15–49 Years Aged Group Among 109 Countries or Territories From 2000 to 2018
Authors: Du Min , Yuan Jie , Jing Wenzhan , Liu Min , Liu Jue 
Published: February 2022

ObjectiveThe prevalent international travel may have an impact on new HIV infections, but related studies were lacking. We aimed to explore the association between international travel arrivals and new HIV infections in 15–49 years aged group from 2000 to 2018, to make tailored implications for HIV prevention.MethodsWe obtained the data of new HIV infections from the Joint United Nations Programme on HIV/AIDS and international travel arrivals from the World Bank. Correlation analysis was used to explore the relation briefly. Log-linear models were built to analyze the association between international travel arrivals and new HIV infections.ResultsInternational travel arrivals were positively correlated with new HIV infections (correlation coefficients: 0.916, p &lt; 0.001). After controlling population density, the median age of the total population (years), socio-demographic index (SDI), travel-related mandatory HIV testing, HIV-related restrictions, and antiretroviral therapy coverage, there were 6.61% (95% CI: 5.73, 7.50; p &lt; 0.001) percentage changes in new HIV infections of 15–49 years aged group associated with a 1 million increase in international travel arrivals.ConclusionsHigher international travel arrivals were correlated with new HIV infections in 15–49 years aged group. Therefore, multipronged structural and effective strategies and management should be implemented and strengthened.
Analisis Kemampuan Komunikasi Matematis Siswa dalam Menyelesaikan Masalah Kontekstual
Authors: Ramdani Ahmad Tri Saum , Upu Hamzah , Arsyad Nurdin 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui deskripsi kemampuan komunikasi matematis siswa dalam menyelesaikan masalah kontekstual. Jenis penelitian ini adalah penelitian deskriptif menggunakan pendekatan kualitatif. Pengambilan subjek penelitian ini adalah siswa kelas XII MIPA. Pengambilan subjek dilakukan dengan memberikan tes kemampuan awal kepada siswa yang kemudian dari hasil tersebut dipilih 4 subjek penelitian berdasarkan kategori yang ada. Instrumen yang digunakan adalah, tes tertulis kemampuan komunikasi matematis pedoman wawancara. Hasil penelitian menunjukkan kemampuan komunikasi tertulis subjek penelitian baik pada indikator kemampuan dalam menuliskan informasi yang terdapat dalam soal dan menentukan tujuan utama yang akan dicapai. Akan tetapi subjek penelitian lemah dalam kemampuan meuliskan operasi matematika sesuai dengan maksud soal, menggunakan gambar ataupun notasi ilmiah dalam menyelesaikan masalah, menyajikan representasi menyeluruh terhadap konsep yang digunakan serta menuliskan kesimpulan jawaban kedalam bahasa sehari-hari. Hasil dari penelitian ini diharapkan dapat menambah wawasan tentang kemampuan komunikasi matematis siswa SMA baik secara lisan ataupun tulisan pada materi khususnya dalam mengerjakan soal kontekstual sehingga dalam proses pembelajaran siswa mampu meningkatkan kemampuan berkomunikasi dalam bahasa matematika.
Kata Kunci: Komunikasi matematis, masalah kontekstual

This study aims to determine the description of the mathematical communication ability of students in solving a contextual problem . This type of research is descriptive research using a qualitative approach. The subject of this research are students of class XII. Retrieval of the subject is performed by providing a test of the initial ability on to students then from the results of the test selected 4 subjects based on existing categories. The instrument used are written mathematical communication ability test and interview guidelines. The results showed the ability of written communication of research subject are writing information contained in the questions and define the main objectives to be achieved. But the subject are weak in the ability meuliskan mathematical operations in accordance with the purpose of questions, use of pictures or scientific notation in solving a problem, presenting a representation of the entire to the concept that is used and write a conclusion answer into daily language. The results of this study are expected to add insight about the mathematical communication ability, especially in working on contextual so that in the process of learning students are able to improve the ability to communicate in the language of mathematics.
Keywords: Mathematical communication, contextual problems
Komparasi Pemahaman Konsep Siswa yang Diajar dengan Metode Mind Mapping dan Metode Guided Note Taking pada Kelas VIII SMP
Authors: Munajah Ishaq , Minggi Ilham , Talib Ahmad 
Published: February 2022

Penelitian ini adalah penelitian eksperimen yang melibatkan dua kelompok yang diberi perlakuan. Penelitian ini bertujuan untuk mengetahui perbedaan pemahaman konsep matematika antara siswa yang diajarkan menggunakan metode Mind Mapping dan metode Guided Note Taking. Sampel penelitian ini terdiri dari dua kelas yang dipilih dengan menggunakan teknik cluster random sampling. Pengumpulan data dilakukan dengan menggunakan instrumen lembar observasi dan tes pemahaman konsep, dan. Data yang terkumpul dianalisis secara deskriptif dan inferensial. Hasil penelitian menunjukkan bahwa terdapat perbedaan signifikan antara peningkatan pemahaman konsep matematika siswa yang diajar dengan metode pembelajaran Mind Mapping dan siswa yang diajar dengan menggunakan metode pembelajaran Guided Note Taking pada kelas VIII.
Kata Kunci: Mind Mapping, Guided Note Taking, Instrumen Tes Pemahaman Konsep, Lembar Observasi, dan Pemahaman Konsep

This study was an experimental study involving two treated groups. This study aims to find out a differences in understanding of mathematical concepts between students taught using the Mind Mapping method and the Guided Note Taking method. The study sample consisted of two classes selected using the cluster random sampling technique . Data collection is done by using observation sheets and concept understanding test instruments. Data collected was analyzed descriptively and inferentially. The results showed that there are significant differences between increasing understanding of mathematical concepts of students taught by Mind Mapping learning methods and students taught using Guided Note Taking learning methods in class VIII.
Keyword: Mind Mapping, Guided Note Taking, Concept Understanding Test Instruments, Observation Sheets and Concept Understanding.
Analisis Kesalahan Mahasiswa dalam Memecahan Masalah Nonrutin pada Materi Fungsi Kuadrat
Authors: Syam Rahmat , Dassa Awi , Khodidah Siti 
Published: February 2022

Penelitian ini adalah penelitian deskriptif dengan pendekatan kualitatif, bertujuan untuk mengetahui gambaran kesalahan yang dilakukan mahasiswa dalam memecahkan masalah nonrutin berupa penerapan materi fungsi kuadrat dalam kehidupan nyata yang ditinjau berdasarkan objek dasar matematika (fakta, konsep, prinsip, operasi). Pengumpulan data utama diperoleh dengan tes dan wawancara. Subjek penelitian ini adalah tiga orang mahasiswa pendidikan matematika UNM yang dipilih dari dua puluh tiga responden yang mengikuti tes tertulis. Analisis data mengikuti model dari Miles and Huberman yang meliputi reduksi data, penyajian data, verifikasi dan penarikan kesimpulan. Hasil penelitian ini sebagai berikut: Kesalahan terbanyak yang dilakukan subjek adalah kesalahan konsep dan operasi, dimana mahasiswa menggunakan rumus yang tidak sesuai dan miskonsepsi dalam mengambil langkah penyelesaian masalah, keliru dalam melakukan perhitungan aljabar dan menggunakan prodesur yang tidak hierarkis. Kemudianl kesalahan prinsip yaitu misinterpretasi masalah dan tidak memperhatikan prasyarat dalam menggunakan rumus. Mahasiswa tidak menggunakan konsep fungsi kuadrat secara spesifik atau tidak mampu menerapkannya sebagai bagian dari langkah pemecahan masalah. Hal ini dikarenakan penguasaan konsep yang kurang dan minimnya pengalaman dalam memecahkan masalah sejenis.
Kata Kunci: Analisis kesalahan, masalah nonrutin, fungsi kuadrat

This study was a descriptive research by using qualitative approach that aimed to describe the errors made by students in quadratic function real life problems based on basic mathematical objects (facts, principles, concepts, and operation). The data collection were obtained by tests and interview. The subjects of this study were three students of mathematics education department in Universitas Negeri Makassar. Data analysis was used Miles and Huberman model: data collection, data reduction, data display, verification and conclusion. The results of this study said that the most mistakes made by subjects were conceptual errors and operation errors; students didn’t use appropriate formulas, misconceptions in choosed steps to solve problems, wrong in algebraic manipulation, and didn’t use hierarchical procedures. Then principle errors; misinterpretation or failed to grasp what the problem ask to and didn’t cognize the preconditions before using the formula. Students were unable to apply quadratic function specifically as part of the problem solving. This is due to the lack of mathematic skills how to carry out their conceptual knowledge to solve problems and lack of experience in solving similar problems.
Keywords: Error analysis, non-routine problems, quadratic functions
Penerapan Metode Latis untuk Mengurangi Kesalahan Siswa dalam Operasi Perkalian Ditinjau dari Kemampuan Awal Siswa
Authors: Chaerunnisa Rifkah , Suradi S. , Asdar A. 
Published: February 2022

Penelitian ini bertujuan untuk mengurangi kesalahan siswa dalam operasi perkalian dengan menerapkan metode perkalian latis. Jenis penelitian ini adalah penelitian kualitatif dengan metode Penelitian Tindakan Kelas (PTK). Subjek penelitian adalah 24 siswa yang dipilih secara purposive. Penelitian dilaksanakan di kelas VII dari salah satu SMP di Parepare. Tahun ajaran 2018/2019. Intrumen penelitian yang digunakan terdiri atas lembar observasi, soal tes, dan angket. Desain PTK menggunakan model Kemmis dan Tanggart yang meliputi perencanaan, tindakan/pelaksanaan, observasi, dan refleksi. Hasil penelitian menunjukkan bahwa Skor rata-rata hasil tes matematika siswa setelah pemberian tindakan pada siklus I adalah 58,33 dari skor ideal 100 dan sebanyak 15 siswa yang melakukan kesalahan dalam operasi perkalian. Sedangkan skor rata-rata hasil tes matematika siswa setelah pemberian tindakan pada siklus II adalah 80,83 dari skor ideal 100 dan sudah tidak ada lagi siswa yang melakukan kesalahan. Kesalahan siswa dalam menyelesaikan soal operasi perkalian bilangan bulat dan bilangan pecahan desimal terdapat tiga aspek kesalahan yaitu kesalahan dalam memahami konsep, kesalahan proses penyelesaian, dan kesalahan penarikan kesimpulan. Sehingga dapat disimpulkan bahwa penerapan metode latis dapat mengurangi kesalahan siswa dalam operasi perkalian ditinjau dari kemampuan awal siswa SMP di ParepareKata kunci: Kesalahan siswa, Operasi perkalian, Metode latis, Kemampuan Awal, PTK . This research aims to reduce the students error in multiplication operation by implementing latis multiplication method. Type of research is qualitative research by classroom action research methods. Research subject are 24 students which selected by purposive which is encountered errors in multiplication operations. This research conducted in class VII.1of on SMP in Parepare Academic year 2018/2019. Classroom action research design by using Kemmis and Tanggart model which includes planning action/ implementation, observation and reflection. The result of research shows that the average score of math test results after giving the action in Cycle is 58.33 from ideal score 100 and there are 15 students which make a mistake in operation the multiplication. While the average score of math test result after giving the action in cycle ii is 80.83 from ideal score 100 and there is no more student that make a mistake. Students error in solving integer multiplication and decimal fraction operation problems there are three error aspects that are in understanding the concept, error solving process and error of inference. So that, it can be conclude that the implementation of latis method can reduce the student error in multiplication operation in terms of the initial abilities of students SMP in Parepare.Keywords: Student errors, multiplication operation, latis method, initial ability, classroom action research
Penyebab Miskonsepsi Siswa Kelas 9 pada Materi Pecahan Bentuk Aljabar Berdasarkan Teori Konstruktivisme
Authors: Djadir D, , Arsyad Nurdin , Kalu Melda Datu 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui faktor penyebab terjadinya miskonsepsi siswa pada materi pecahan bentuk aljabar kelas 9 ditinjau dari prinsip-prinsip teori belajar konstruktivisme.Jenis penelitian ini adalah penelitian kualitatif dengan menggunakan pendekatan deskriptif. Subjek dalam penelitian ini adalah 5 siswa kelas 9 yang mengalami miskonsepsi terbanyak dengan nilai terendah. Instrumen yang digunakan dalam penelitian ini adalah tes diagnostik miskonsepsi siswa yang terdiri dari beberapa butir soal uraian disertai dengan skor tingkat kepercayaan (CRI) dan pedoman wawancara. Prinsip-prinsip teori belajar konstruktivisme yang dimaksud dalam penelitian ini adalah lingkungan belajar, pengetahuan awal siswa, kemampuan siswa, keaktifan siswa dalam pembelajaran dan pengalaman belajar siswa. Hasil penelitian menunjukkan bahwa terjadinya miskonsepsi disebabkan oleh beberapa faktor baik dari segi internal maupun eksternal ditinjau dari prinsip-prinsip teori konstruktivisme.Kata Kunci:Miskonsepsi, Konstruktivisme, CRI, Pecahan, AljabarThis study aims to determine the factors that cause student misconceptions form 9th grade on algebraic form fraction in terms of the principles of constructivism learning theory. This type of research is qualitative research using a descriptive approach. The subjects in this study were 5 grade 9 students who experienced the most misconceptions with the lowest scores. The instrument used in this study was a student misconception diagnostic test consisting of several descriptive items accompanied by Certainty of Response Index (CRI) and an interview guide. The principles of constructivism learning theory referred to in this study are the learning environment, students' initial knowledge, student abilities, student activeness in learning and student learning experiences. The results showed that the misconception was caused by several factors, both internal and external, in terms of the principles of constructivism theory.Keywords:Misconception, Constructivism, CRI, Algebraic, Fractions
Analisis Pengaruh Dana Pihak Ketiga, Total Aset, dan Non-Performing Finance Terhadap Pembiayaan Bagi Hasil
Authors: Harianto Syawal , Siregar Saparuddin , Sugianto  
Published: February 2022

The purpose of this study is to know and analyze the factors that affect total revenue-sharing financing in sharia business units in Indonesia. These factors are Third Party Funds (DPK), Non-Performing Financing (NPF), and Total Assets (TA). The data used in this study is panel data with the period 2010-2020 published by the Financial Ministry and in the annual financial statements of Islamic banking. The population of 21 companies with a sample of 5 companies with purposive sampling methods. The analysis tools used are Eviews10 and SPSS 18. The analysis technique in this study is a regression of panel data by testing using a fixed-effect model. The results of this study showed that DPK, NPF, and simultaneously had a significant effect on total revenue-sharing financing in sharia business units in Indonesia. The results of the study partially showed that the variables of DPK and TA had a significant positive effect on the total financing in the Sharia Business Unit in Indonesia. The NPF variable does not have a significant negative effect on the total financing in the Sharia Business Unit in Indonesia. The results of the R-Square adjusted value showed a value of 51.9%.
The Effect Of Green Organizational Culture And Green Reward On Organizational Citizenship Behavior With Organizational Commitment As Intervening Variables
Authors: Norma Sari Putri Audi , Mustafa E. Q Zainal 
Published: February 2022

Green Human Resources Management (GHRM), known as "environmental" human resource management, is considered an essential tool for the successful implications of organizational sustainable development strategies. The purpose of this study were to analyze first the effect of green organizational culture and green rewards on organizational commitment. The second is to analyze the effect of organizational commitment and green organizational culture on organizational citizenship behavior. The third is to analyze the effect of green organizational culture and green rewards on organizational citizenship behavior through organizational commitment. This research are a quantitative research that used 105 employees, who were determined by using the purposive sampling method as the sample. Data was obtained through the distribution of questionnaires. The analytical tool used in this study uses IBM SPSS software 21. The results show that green organizational culture and green reward have a positive effect on an organizational commitment. Organizational commitment has a positive effect on organizational citizenship behavior, the higher the organizational commitment, the higher the organizational citizenship behavior. The results of further hypothesis testing showed that green organizational culture and green rewards have a positive effect on organizational citizenship behavior through organizational commitment.