bluuebunny/crossref_metadata_2025_split huggingface dataset:
Music and Deafness in the Nineteenth-Century U.S. Imagination
Authors: Maler Anabel 
Published: April 2022

AbstractThis article argues that deaf musical knowledge became epistemically excluded from systems of musical thought in the United States as the result of a battle between two competing philosophies of deaf education in the nineteenth century: manualism and oralism. It reveals how oralist educators explicitly framed music as exclusively involving “normal hearing”—and thus as outside of deaf knowledge except through technological intervention—by drawing on ideas about eugenics, race, and authenticity. Ideas about morality and technology also colored views of deaf musicality in the United States, shaping the reception of deaf music-making throughout the twentieth century until today. This article tells the story of how deaf music-making came to be forgotten and discovered, again and again, in the U.S. consciousness. By way of conclusion, I suggest that in order to address the epistemic exclusion of deaf musical knowers, we must carefully attend to what deaf epistemologies bring to music studies.
Religious Freedom in the City Pool: Gender Segregation, Partisanship, and the Construction of Symbolic Boundaries
Authors: Argyle Lisa P. , Terman Rochelle , Nelimarkka Matti 
Published: April 2022

AbstractLow political support for religious minority groups in the United States is often explained as a matter of social distance or unfamiliarity between religious traditions. Observable differences between beliefs and behaviors of religious minority groups and the cultural mainstream are thought to demarcate group boundaries. However, little scholarship has examined why some practices become symbolic boundaries that reduce support for religious accommodation in public policy, while nearly identical practices are tolerated. We hypothesize that politics is an important component of the process by which some religious practices are transformed into demarcations between “us” and “them.” We conduct an original survey experiment in which people are exposed to an identical policy demand—women-only swim times at a local public pool—attributed to three different religious denominations (Muslim, Jewish, and Pentecostal). We find that people are less supportive of women-only swim times when the requesting religion is not a part of their partisan coalition.
The varying logics for supporting populist right-wing welfare politics in West European welfare regimes
Authors: Loxbo Karl 
Published: April 2022

AbstractLittle is known about whether and under which conditions populist radical right parties’ (PRRPs’) nativist welfare politics matters to the voters. I address this gap in the research and test the argument that the electoral appeal of this electoral discourse varies among welfare regimes. The study compares the conservative and social-democratic welfare regimes and focuses on the vote choices of the two core constituencies of PRRPs – economically exposed and immigration-sceptic voters. The results show that these electorates support PRRPs’ nativist welfare positions for very different reasons in the two welfare regimes. First, in the conservative regime, economically exposed citizens vote for PRRPs, the more they stress nativism and welfare expansion. By contrast, in the social-democratic regime this group of voters is more likely to support positions combining nativism and dismantled welfare benefits. Second, immigrant-sceptic voters in the social-democratic regime support PRRPs who pledge to preserve the welfare state, and increased migration considerably boosts the probability that they do so. By contrast, this group of voters in the conservative regime is more likely to support PRRPs who seek to partly dismantle the welfare state, and the inflow of immigrants is unrelated to these choices. These results have important implications and suggest that welfare regimes moderate public opinion differently in the current age of populism compared to previous eras.
Thermal Response to Tropical Cyclones Over the Kuroshio
Authors: He Shunzhi , Cheng Xiaoping , Fei Jianfang , Wei Zexun , Huang Xiaogang , Liu Lei 
Published: April 2022

AbstractThe sea surface temperature (SST) and surface enthalpy flux response to tropical cyclones (TCs) in the Kuroshio are investigated using 18‐year observational datasets. The statistical results show that the maximum TC‐induced SST cooling and its occurrence time, recovery time, spatial patterns of the SST anomaly, and the surface enthalpy flux anomaly between the Kuroshio and the warm core eddies (WCEs) and typical oceanic water (i.e., eddy‐free and Kuroshio‐free, TOW) varies considerably. Specifically, the Kuroshio suppresses TC‐induced SST cooling more so than the WCE. The Kuroshio can make the maximum SST cooling occur approximately half a day sooner than that in the WCE and TOW. The recovery time is also shorter in the presence of the Kuroshio and is more pronounced with increasing SST reduction. Compared to the cold wake in the TOW, the composited SST decrease exhibits a long strip with a width of approximately 2° in the presence of the Kuroshio, rather than having a circular distribution of SST decrease as in the WCE. In the recovery period, the negative SST anomaly propagates leftward slowly under TOW conditions, whereas the negative SST anomaly shifts rightward gradually in the Kuroshio condition. Similarly, the air‐to‐sea flux anomaly propagates rightward slowly in the Kuroshio, which moves leftward in the WCE and TOW. These results emphasize that the impact of the Kuroshio on the tropical cyclone‐induced SST anomaly and the surface enthalpy flux anomaly cannot be ignored.
Deformation Process and Mechanism of the Frontal Megathrust at the Nankai Subduction Zone
Authors: Kimura Gaku , Hamada Yohei , Yabe Suguru , Yamaguchi Asuka , Fukuchi Rina , Kido Yukari , Maeda Lena , Toczko Sean , Okuda Hanaya , Ogawa Nobuhiro , Morioka Hitoshi , Ujiie Kohtaro , Saffer Demian 
Published: April 2022

AbstractThe frontal megathrust of the Nankai Trough subduction zone is recognized as a seismogenic fault based on a record of frictional heating, but the underlying micromechanical processes that act on the fault surface are poorly known. Here we present a layer of fault gouge ∼2 mm thick within a core drilled across the megathrust, in which smectite‐rich siltstone has been transformed into a preferentially oriented illite aggregate. The nearly complete breakdown of smectite is consistent with fast frictional heating on this fault; however, the microtextures of the gouge and its surroundings are asserted one produced experimentally by slow slip. We suggest that slow slip with small shear strain has overprinted the textures produced by the previous faster and larger slip. This interpretation based on microtectonic evidence suggests a slow slip around the frontal megathrust took place during slow down, afterslip, or interseismic as observed now going in subduction zone. We suggest that the illite‐dominated gouge is conditionally stable, likely to shift from rapid to slow slip at different times.
Uncertainty Characterization of Ground‐Based, Satellite, and Reanalysis Snow Depth Products Using Extended Triple Collocation
Authors: Qiao Dejing , Li Zhen , Zeng Jiangyuan , Liang Shuang , McColl Kaighin A. , Bi Haiyun , Zhou Jianmin , Zhang Ping 
Published: April 2022

AbstractThe optimal use of hemispheric‐scale snow depth (SD) products for various hydrometeorological applications requires a comprehensive assessment of their quality. Most previous validation studies of SD products adopted in situ observations as the ground truth, which may cause representativeness errors due to spatial scale mismatch between point‐based ground SD measurements and grid‐based SD products. The extended triple collocation (ETC) technique is a powerful tool to estimate the uncertainty of three independent data sets without assuming any one data source is an error‐free “truth” reference. This study first used the ETC to assess the uncertainty of three types of hemispheric‐scale SD products, including the ground‐based analysis Canadian Meteorological Centre (CMC), the satellite‐based Advanced Microwave Scanning Radiometer 2 (AMSR2), and the model‐based Global Land Data Assimilation System (GLDAS) SD products. Furthermore, the uncertainties of each SD product were analyzed using ETC metrics, that is, the correlation coefficient (R) and error standard deviations (STDs), with respect to several environmental and perturbing factors. Overall, the CMC outperforms the AMSR2 and GLDAS, with a higher R and a smaller STD. Considering multiple environmental and perturbing factors, the poorest performance of the three SD products is mainly found in densely vegetated regions, and they are strongly related to the forest cover fraction and surface roughness. Despite the above factors, the best performance for all three SD products is found over temperate climate regions. The results demonstrate the usefulness of the ETC approach to quantify the uncertainty of SD products particularly in remote regions with sparse in situ measurements.
Hierarchical Bayesian Inversion of Global Variables and Large‐Scale Spatial Fields
Authors: Wang Lijing , Kitanidis Peter K. , Caers Jef 
Published: April 2022

AbstractBayesian inversion is commonly applied to quantify uncertainty of hydrological variables. However, Bayesian inversion is usually focused on spatial hydrological properties instead of hyperparameters or non‐gridded physical global variables. In this paper, we present a hierarchical Bayesian framework to quantify uncertainty of both global and spatial variables. We estimate first the posterior of global variables and then hierarchically estimate the posterior of the spatial field. We propose a machine learning‐based inversion method to estimate the joint distribution of data and global variables directly without introducing a statistical likelihood. We also propose a new local dimension reduction method: local principal component analysis (local PCA) to update large‐scale spatial fields with local data more efficiently. We illustrate the hierarchical Bayesian formulation with three case studies: one with a linear forward model (volume averaging inversion) and two with non‐linear forward models (pumping tests and hydraulic head measurements), including a 3D case. Results show that quantifying global variables uncertainty is critical for assessing uncertainty on predictions. We show how the local PCA approach accelerates the inversion process. Furthermore, we provide an open‐source Python package (https://github.com/lijingwang/hierarchicalBayes.git) on the hierarchical Bayesian framework including three case studies.
Interrogating Subsurface Structures Using Probabilistic Tomography: An Example Assessing the Volume of Irish Sea Basins
Authors: Zhao Xuebin , Curtis Andrew , Zhang Xin 
Published: April 2022

AbstractThe ultimate goal of a scientific investigation is usually to find answers to specific, often low‐dimensional questions: what is the size of a subsurface body? Does a hypothesized subsurface feature exist? Existing information is reviewed, an experiment is designed and performed to acquire new data, and the most likely answer is estimated. Typically the answer is interpreted from geological and geophysical data or models, but is biased because only one particular forward function is considered, one inversion method is applied, and because human interpretation is a biased process. Interrogation theory provides a systematic way to answer specific questions by combining forward, design, inverse, and decision theories. The optimal answer is made more robust since it balances multiple possible forward models, inverse algorithms and model parametrizations, probabilistically. In a synthetic test, we evaluate the area of a low‐velocity anomaly by interrogating Bayesian tomographic results. By combining the effect of four inversion algorithms, the optimal answer is very close to the true answer, even on a coarsely gridded parametrization. In a field data test, we evaluate the volume of the East Irish Sea basins using probabilistic 3D shear wave speed depth inversion results. This example shows that interrogation theory provides a useful way to answer realistic questions about the Earth. A key revelation is that while the majority of computation may be spent solving inverse problems, much of the skill and effort involved in answering questions may be spent defining and calculating target function values in a clear and unbiased manner.
Planetary Aeolian Landforms: An Introduction to the Fifth Planetary Dunes Workshop Special Issue
Authors: Silvestro S. , Titus T. N. 
Published: April 2022

AbstractAeolian landforms are widespread in our solar system. Understanding the exact nature and processes of formation of these features are challenging tasks necessitating a strong collaboration between scientists with different skills and scientific backgrounds. This paper describes the special issue for the 5th International Planetary Dunes Workshop, which includes 15 research papers and three commentaries. Among the 18 papers included in this collection, 16 cover Martian aeolian science and two Titan aeolian science. The papers presented focus on bedform morphology and dynamics via remote sensing data, modeling, analogs studies and laboratory experiments. Here we put the main results of the papers in their appropriate scientific context and discuss potential future lines of research.
Experiences of children with central venous access devices: a mixed-methods study
Authors: Ullman Amanda J. , Kleidon Tricia M. , Gibson Victoria , Takashima Mari , Schults Jessica , Cattanach Paula , Paterson Rebecca , Cooke Marie , Byrnes Joshua , Saiyed Masnoon , Chopra Vineet , Rickard Claire 
Published: April 2022

Abstract
Background
Our study aims to explore the experience of having a central venous access device (CVAD) from the perspective of the child and family and how movements within and outside of hospital environments influence this experience.

Methods
A mixed-methods study was conducted across Children’s Health Queensland (Australia), including inpatient and home-care settings. Children less than 18 years with CVADs were eligible and followed for 3 months or CVAD removal. A subgroup of primary caregivers participated in semi-structured interviews. Quantitative and qualitative measures of child and family CVAD experiences were explored.

Results
In total, 163 patients with 200 CVADs were recruited and followed for 6993 catheter days (3329 [48%] inpatients; 3147 [45%] outpatients; 517 [7%] home). Seventeen participants were interviewed. Experiences of having a CVAD were complex but predominantly positive primarily related to personalized CVAD care, healthcare quality, and general wellbeing. Their experience was shaped by their movements through hospital and home environments, including care variation and distress with procedures. Device selection and insertion location further influenced experience, including safety, impairments in activities of daily living, school, and recreation.

Conclusions
CVAD experiences were influenced by nonmodifiable (e.g., diagnosis) and modifiable factors (e.g., education; care variation). Clinical approaches and policies that account for family and child considerations should be explored.

Impact

Variation in decision making and management for pediatric CVADs is accepted by many clinicians, but the influence this variation has on the health experience of children and their families is less well explored.

This is the first study to draw from a broad range of children requiring CVADs to determine their experience within and outside of healthcare facilities.

Interdisciplinary clinicians and researchers need to work collaboratively with children and their families to provide resources and support services to ensure they have positive experiences with CVADs, no matter where they are managed, or who they are managed by.
Single nucleotide polymorphism determines constitutive versus inducible type VI secretion in Vibrio cholerae
Authors: Drebes Dörr Natália C , Proutière Alexis , Jaskólska Milena , Stutzmann Sandrine , Bader Loriane , Blokesch Melanie 
Published: April 2022

Abstract
Vibrio cholerae is a well-studied human pathogen that is also a common inhabitant of marine habitats. In both environments, the bacterium is subject to interbacterial competition. A molecular nanomachine that is often involved in such competitive behavior is the type VI secretion system (T6SS). Interestingly and in contrast to non-pandemic or environmental isolates, the T6SS of the O1 El Tor clade of V. cholerae, which is responsible for the ongoing 7th cholera pandemic, is largely silent under standard laboratory culture conditions. Instead, these strains induce their full T6SS capacity only under specific conditions such as growth on chitinous surfaces (signaled through TfoX and QstR) or when the cells encounter low intracellular c-di-GMP levels (TfoY-driven). In this study, we identified a single nucleotide polymorphism (SNP) within an intergenic region of the major T6SS gene cluster of V. cholerae that determines the T6SS status of the cell. We show that SNP conversion is sufficient to induce T6SS production in numerous pandemic strains, while the converse approach renders non-pandemic/environmental V. cholerae strains T6SS-silent. We further demonstrate that SNP-dependent T6SS production occurs independently of the known T6SS regulators TfoX, QstR, and TfoY. Finally, we identify a putative promoter region adjacent to the identified SNP that is required for all forms of T6SS regulation in V. cholerae.
SLC25A38 as a novel biomarker for metastasis and clinical outcome in uveal melanoma
Authors: Fan Zhongyi , Duan Jingjing , Luo Pu , Shao Ling , Chen Qiong , Tan Xiaohua , Zhang Lei , Xu Xiaojie 
Published: April 2022

AbstractRisk of metastasis is increased by the presence of chromosome 3 monosomy in uveal melanoma (UM). This study aimed to identify more accurate biomarker for risk of metastasis in UM. A total of 80 patients with UM from TCGA were assigned to two groups based on the metastatic status, and bioinformatic analyses were performed to search for critical genes for risk of metastasis. SLC25A38, located on chromosome 3, was the dominant downregulated gene in metastatic UM patients. Low expression of SLC25A38 was an independent predictive and prognostic factor in UM. The predictive potential of SLC25A38 expression was superior to that of pervious reported biomarkers in both TCGA cohort and GSE22138 cohort. Subsequently, its role in promoting metastasis was explored in vitro and in vivo. Knock-out of SLC25A38 could enhance the migration ability of UM cells, and promote distant metastasis in mice models. Through the inhibition of CBP/HIF-mediated pathway followed by the suppression of pro-angiogenic factors, SLC25A38 was situated upstream of metastasis-related pathways, especially angiogenesis. Low expression of SLC25A38 promotes angiogenesis and metastasis, and identifies increased metastatic risk and worse survival in UM patients. This finding may further improve the accuracy of prognostic prediction for UM.
Loss of RNA binding protein HuD facilitates the production of the senescence-associated secretory phenotype
Authors: Ryu Seungyeon , Jung Myeongwoo , Kim Chongtae , Kang Hoin , Han Sukyoung , Cha Seongho , Jeong Seung Min , Lee Eun Kyung 
Published: April 2022

AbstractHuD, an RNA binding protein, plays a role in the regulation of gene expression in certain types of cells, including neuronal cells and pancreatic β-cells, via RNA metabolism. Its aberrant expression is associated with the pathogenesis of several human diseases. To explore HuD-mediated gene regulation, stable cells expressing short hairpin RNA against HuD were established using mouse neuroblastoma Neuro2a (N2a) cells, which displayed enhanced phenotypic characteristics of cellular senescence. Two approaches, RNA immunoprecipitation (RNA IP)-NanoString profiling and cytokine array, were used to subsequently identify a subset of putative HuD targets that act as senescence-associated secretory phenotype (SASP), including C-C motif ligand 2 (CCL2), CCL20, C-X-C motif chemokine ligand 2 (CXCL2), and interleukin-6 (IL-6). Here, we further demonstrated that HuD regulates the expression of CCL2, a SASP candidate upregulated in cells following HuD knockdown, by binding to the 3′-untranslated region (UTR) ofCcl2mRNA. Downregulation of HuD increased the level of CCL2 in N2a cells and the brain tissues of HuD knockout (KO) mice. Exposure to γ-irradiation induced cellular senescence in N2a cells and HuD knockdown facilitated stress-induced cellular senescence. Our results reveal that HuD acts as a novel regulator of CCL2 expression, and its aberrant expression may contribute to cellular senescence by regulating SASP production.
Long noncoding RNA SH3PXD2A-AS1 promotes NSCLC proliferation and accelerates cell cycle progression by interacting with DHX9
Authors: Zhou Yeqing , Yong Hongmei , Cui WenJie , Chu Sufang , Li Minle , Li Zhongwei , Bai Jin , Zhang Hao 
Published: April 2022

AbstractAs the most commonly diagnosed lung cancer, non–small cell lung carcinoma (NSCLC) is regulated by many long noncoding RNAs (lncRNAs). In the present study, we found that SH3PXD2A-AS1 expression in NSCLC tissues was upregulated compared with that in normal lung tissues in The Cancer Genome Atlas (TCGA) database by using the GEPIA website. K-M analysis was performed to explore the effects of this molecule on the survival rate in NSCLC. The results demonstrated that SH3PXD2A-AS1 expression was increased in human NSCLC, and high SH3PXD2A-AS1 expression was correlated with poor overall survival. SH3PXD2A-AS1 promotes lung cancer cell proliferation and accelerates cell cycle progression in vitro. Animal studies validated that knockdown of SH3PXD2A-AS1 inhibits NSCLC cell proliferation in vivo. Mechanically, SH3PXD2A-AS1 interacted with DHX9 to enhance FOXM1 expression, promote tumour cell proliferation and accelerate cell cycle progression. Altogether, SH3PXD2A-AS1 promoted NSCLC growth by interacting with DHX9 to enhance FOXM1 expression. SH3PXD2A-AS1 may serve as a promising predictive biomarker for the diagnosis and prognosis of patients with NSCLC.