bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of unintentional coronary angiography on outcomes of emergency surgery in acute type A aortic dissection: a retrospective study
Authors: Peng Hao , Liu Wei , Jian Kai-Tao , Xia Yu , Liu Jian-Shi , Sun Li-Zhong , Mei Yun-Qing 
Published: April 2022

Abstract
Background: This study investigated the impact of coronary angiography on outcomes of emergency operation in acute type A aortic dissection (ATAAD) patients who were initially misdiagnosed as the acute coronary syndrome.Methods: From October 2016 to April 2019, 129 patients underwent surgery for ATAAD in our institution, including 21 patients (16.3%, CA group) who received preoperative coronary angiography without knowledge of the ATAAD, and the rest 108 did not (NCA group). Preoperative clinical characteristics, surgical mortality and postoperative complications were compared. Multivariable logistic regression was performed to confirm the independent prognostic factors for short-term and long-term outcomes.Results: Patients undergoing coronary angiography had higher prevalence of preoperative hypotension or shock (61.9% vs 35.2%, P=0.022), ischemic changes on electrocardiogram (66.7% vs 37.0%, P=0.012), platelet inhibition (ADP-induced inhibition 92.0% vs 46.0%, P=0.001), and coronary involvement (66.7% vs 30.6%, P=0.002). 30-day/in-hospital mortality was 4.8% versus 9.3% (P=0.84). CA group had more intraoperative bleeding (1900ml vs 1500ml, P=0.013) and chest-tube drainage on the first postoperative day (1040ml vs 595ml, P=0.028). However, preoperative coronary angiography was not independent risk factors for surgical mortality (OR 0.171, 95%CI 0.013-2.174, P=0.173) and overall survival (HR 0.407; 95%CI 0.080-2.057; P=0.277). Conclusion: Patients undergoing coronary angiography carried a higher risk of preoperative hemodynamic instability, myocardial ischemia, and perioperative bleeding. However, unintentional coronary angiography did not have a significant impact on short-term and long-term outcomes of emergency surgery in ATAAD.
Ensete superbum Roxb Cheesman (wild banana) peel extract ameliorates 2, 4, 6- trinitrobenzenesulfonic acid-induced colitis in rats
Authors: Mathew Nimisha Sarah , Muthukumar S. P. , Bettadaiah B. K. , Negi Pradeep Singh 
Published: April 2022

Abstract
The wild banana plant Ensete superbum Roxb. Cheesman is widely used as traditional remedy among indigenous populations to relieve inflammation, stomachache and diarrhea. Earlier studies have revealed the in-vitro anti-cancer effects of peel dioxane fraction (PD) extracted from ripe peel aqueous extract (PA) of E. superbum on human colorectal adenocarcinoma cell lines. However, its gastro protective effect in complications of the inflammatory bowel disease (IBD) such as Ulcerative colitis (UC) has not been investigated. In the present work, the oral toxicity of PD was assessed, and its ameliorative effect in an animal model of ulcerative colitis was explored. In the acute and sub-acute toxicity trials, PD fraction's oral administration did not cause fatalities, and no notable changes relative to control were observed. The No-Observed Adverse Effect Level (NOAEL) of the PD fraction was assessed to be higher than 2000 mg/kg/day in rats. The ameliorative effect of varying concentration of PD fraction (100, 250 and 500 mg/k.g/b.w) in 2,4,6-trinitrobenzene sulfonic acid (TNBS) induced (intra-rectal administration) ulcerative colitis in rats was evaluated by comparing with the standard drug Sulfasalazine (100 mg/kg/b.w). Colon tissue ulceration with significant mucosal damage was observed in colitis rats, which waned in rats treated with PD fraction (500 mg/kg/b.w.), similar to that of rats treated with the sulfasalazine drug. The antioxidant, anti-proliferative, and anti-inflammatory capabilities of PD fraction may explain its protective impact; however, more study is needed to unravel the mechanisms of these pathways.
Assessing of the Therapeutic Efficacy of These 2 Treatment Regimens in the Management of Helicobacter pylori Infection in Kinshasa, Democratic Republic of the Congo: A Prospective cohort study
Authors: Tshimpi Antoine W. , Ngoma Patrick , Nkodila Aliocha N. , Mbendi Charles , Beia Aurore , Paka Youyou , Kipiatu Jean Paul , Monsere Trésor , Kengibe Pitshou , Matimbo Jean Jacques , Nganga Mireille N. , Longo-Mbenza Benjamin 
Published: April 2022

Abstract
BackgroundHelicobacter pylori (Hp) infection is a worldwide public health problem. Unfortunately, its management poses a problem because of resistance to antibiotics. However, there are codified treatment protocols covering sequential and concomitant quadritherapy with regard to first-line probabilistic treatment. The aim of this study was to assess the therapeutic efficacy of these 2 treatment regimens in the management of Hp infection at Kinshasa.MethodsThis was a mixed study, with documentary, descriptive and interventional approaches, carried out between September 1, 2018 and April 30, 2020.ResultsSixty-four patients were collected, including 36 men against 28 women with a sex ratio of 1H:1F; the mean age was 54 ± 16.5 years. There was an over-representation of senior patients (n = 29); an intermediate number of adult patients (n = 22) and a lower number of young patients (n = 13). 34 and 30 were respectively treated according to the concomitant and sequential regimens. Concomitant quadruple therapy offered an eradication rate of 91.2% compared to 56.7% for sequential quadruple therapy; concomitant treatment, advancing age and absence of risky behavior more quickly predicted the occurrence of eradication success.ConclusionThe present study showed superiority of concomitant quadruple therapy over sequential quadruple therapy in first-line treatment. Alcohol with active smoking had a negative influence, while concomitant quadruple therapy, advancement in age had a positive influence on the success of the eradication of Hp infection.
Investigation of interfacial heat transfer characterization for TC4 alloy in triple-layer sheet hot stamping process
Authors: Zhou Jing , Yang Xiaoming , Wang Baoyu , Mu Yanhong 
Published: April 2022

Abstract
During the hot stamping process, heat exchange always occurs between the hot sheet and cold tools. The interfacial heat transfer in the whole forming process will not only affects the forming quality of the parts but also partially determines their post-form mechanical properties and microstructure distribution. As an essential parameter, the interface heat transfer coefficient (IHTC) is of great significance for the prediction of temperature fields in the finite element simulations, especially for the novel forming process named triple-layer sheet hot stamping. In this study, the triple-layer sheet heat exchange experiment is carried out to investigate the interfacial heat transfer behavior of the titanium alloy sheet in the triple-layer sheet hot stamping process. The effects of contact pressure, cladding steel sheet thickness, and contact gap on the interfacial heat transfer behavior and post-form mechanical properties of titanium alloy sheet are analyzed, and the interface heat transfer coefficient between the titanium alloy and high-strength steel sheets is calculated. The finite element model of triple-layer sheet heat transfer is established to verify the accuracy of the calculated interfacial heat transfer coefficient. The results show that the upper and lower steel sheets maintain the temperature of the titanium alloy sheets at a higher level in the triple-layer sheet hot stamping compared with the single-layer one. The temperature of the titanium alloy sheet under the single-layer hot stamping decreases from 900°C to 781.6°C after transferring, a decrease of 118.4°C. The temperature of the titanium alloy sheet only declines by 57.5°C during this period in the triple-layer sheet hot stamping process. In addition, the titanium alloy parts obtained by the triple-layer sheet hot stamping process have better mechanical properties. The IHTC increases with the increase of contact pressure and decreases with the increase of steel sheet thickness and contact gap. The accuracy of the calculated IHTC between the titanium alloy and cladding steel sheets is validated by comparing the results of the experiment and simulation. The maximum error between the simulation results and the experimental measurements is 5.5%.
Design of mutually coupled circuit employing voltage differencing transconductance amplifiers (VDTAs)
Authors: SAYDAM Fatih , KAÇAR Fırat , ÖZER Emre 
Published: April 2022

Abstract
This paper presents a new mutually coupled circuit (MCC) employing voltage differencing transconductance amplifiers (VDTAs), firstly. The proposed circuit consists of two VDTAs, two grounded capacitors, and a single resistor. The inductances can be adjusted independently and electronically. Only one matching condition is required to achieve symmetrical coupling. The time-domain and frequency-domain simulation results confirm the theoretical analysis. An application example is given to demonstrate the functionality of the circuit.
Evaluation of outcomes in the management of primary sporadic desmoid type fibromatosis at a specialist soft tissue sarcoma unit
Authors: Khan Misbah , Almond Max , Ford Samuel , Desai Anant 
Published: April 2022

Abstract
Background: Desmoids are rare fibroblastic tumours whose treatment in any individual case presents a persistent challenge. We endeavoured to evaluate various clinicopathological factors contributing to tumour behaviour. Methods: This is a retrospective review of 95 primary truncal sporadic fibromatosis managed between 2011 and 2020. We studied progression rate for wait and watch(WW) and recurrence rate for the surgically treated group. Relevant event-free survivals and potential risk factors were analysed over a median length of follow-up of 27 months. Results: 66 patients (69.5%) received watchful surveillance and 28 upfront surgery. 2-year progression-free survival in WW group (88.9%) was higher than RFS in the surgical group (77.1%) p=0.02. Adverse event rate compared favourably, 28.8% in WW and 28.6% in surgical group. At final follow-up, rate of stable disease for WW was 47%, and the regression rate was 24.2 %. On Cox regression analysis, meantime to progress was 14+2.0 months, with larger tumour size as a significant prognostic indicator(p= 0.05). Surgical group's mean time to recurrence was 13.8+2.76 months, with tumour location a significant contributing factor(p=0.05). Conclusions: This study confirms to the safety of both treatment approaches. Adverse event rates remained comparable, but event-free survival was longer for the watchful surveillance group.
Response surface methodology mediated process optimization of hexavalent chromium removal from water using spent tea leaves treated with ascorbic acid
Authors: Zaib Qammer , Kyung Daeseung 
Published: April 2022

Abstract
Spent tea leaves were functionalized with ascorbic acid to obtain treated tea waste (t-TW) for adsorption of hexavalent chromium (Cr(VI)) from water. The adsorption removal of Cr(VI) was systematically investigated as a function of four experimental factors i.e. pH (2–12), initial Cr(VI) concentration (1- 100 mg.L− 1), t-TW dosage (0–4 g.L− 1), and temperature (10–50°C) by following statistical experimental design. Response surface methodology (RSM) based central composite rotatable experimental design was opted to establish an empirical model which assessed individual and combined effects of factors on the response; adsorption removal of Cr(VI). The model was experimentally verified and statistically validated by analysis of variance (ANOVA) before using to predict optimal adsorption removal of Cr(VI) from water. It was observed that, at optimized conditions, ≥ 99% of 1 mg.L− 1 Cr(VI) can be removed by 4 g.L− 1 t-TW at pH = 9. The adsorption mechanism was assessed by performing kinetics and equilibrium studies. The adsorption of Cr(VI) on t-TW followed pseudo-second-order kinetics model and could be described by Langmuir and Temkin isotherms; indicating monolayer adsorption and predominant adsorbate-adsorbent interaction. These results encourage the utilization of tea-waste for hazardous metal contaminant removal from aqueous systems.
Frequency of intake of dietary fiber food groups, its determinants, and the relationship with hyperkalemia in hemodialysis patients in a multicenter study
Authors: Nerbass Fabiana Baggio , Scatone Natalia K , Malinovski Juliana , Sczip Andrea C , Oliveira Jorgiane C , Morais Jyana G , Ramos Christiane I , Santos Rafaela G 
Published: April 2022

Abstract
Purpose: Patients undergoing hemodialysis (HD) treatment can have a low intake of dietary fiber-rich food groups to decrease hyperkalemia risk. This multicenter cross-sectional study aimed to investigate the frequency of intake of dietary fiber sources, its determinants, and the relationship with hyperkalemia in HD patients. Methods: HD patients from four dialysis clinics answered a food frequency questionnaire (FFQ) involving the main dietary fiber sources with seven frequency possibilities. The answers were converted into scores. Each score point corresponded to one time per week. Demographic, nutritional, and laboratory data were obtained from the medical records. Univariate analysis was used to assess total score associations, and variables with P<0.20 were included in the regression analysis model.Results: A total of 305 HD patients were included (male: 51%; age: 52.2±14.7 years; hyperkalemia: 29%). The median (interquartile) FFQ scores were as follows: fruits, 6 (2–14); vegetables, 6 (3–10); legumes, 3 (1–7); whole-grain, 0 (0–1); and seeds, 0 (0–0); total score, 19 (14–28). No difference was found between the dietary fiber food groups and total scores with hyperkalemia. Independent predictors of dietary fiber total score were older age, higher HD vintage, higher body mass index (BMI), and higher educational level.Conclusion: The usual frequency of dietary fiber food groups intake was low, and its independent determinants were age, HD vintage, BMI, and education. The lack of association with hyperkalemia suggests that other dietary sources and clinical factors should be considered when managing hyperkalemia in this population.
Diagnostic value of plasma p-tau181, NfL and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias
Authors: Parchi Piero , Baiardi Simone , Quadalti Corinne , Mammana Angela , Valle Sofia Della , Zenesini Corrado , Sambati Luisa , Pantieri Roberta , Polischi Barbara , Romano Luciano , Suffritti Matteo , Bentivenga Giuseppe Mario , Randi Vanda , Stanzani-Maserati Michelangelo , Capellari Sabina 
Published: April 2022

Abstract
Background. Increasing evidence support the clinical implementation of plasma biomarkers of neurodegeneration and neuroinflammation for the screening and diagnosis of patients with dementia. However, confirmatory studies are required to demonstrate their usefulness in the real-world clinical setting, in which co-existence of multiple pathologies in dementia is common.Methods. We evaluated plasma and cerebrospinal fluid (CSF) samples from consecutive patients with frontotemporal dementia (FTD) (n=59), progressive supranuclear palsy (PSP) (n=31), corticobasal syndrome (CBS) (29), dementia with Lewy bodies (DLB) (49), and Alzheimer disease (AD) (n=97). Plasma samples from 60 healthy controls were also analysed. We measured neurofilament light chain (NfL), phospho-tau181 (p-tau181), and glial fibrillary acid protein (GFAP) using Simoa (all plasma biomarkers and CSF GFAP), CLEIA (CSF p-tau181), and ELISA (CSF NfL) assays. To assess the effect of AD and Lewy body co-pathologies, we stratified the non-AD groups according to the A/T/N classification and the results of the CSF alpha-synuclein real-time quaking-induced conversion assay.Results. We found good correlations between CSF and plasma biomarkers for NfL (rho=0.651, p<0.001) and p-tau181 (rho=0.637, p<0.001). Plasma NfL was significantly higher in disease groups than in HC, and showed a greater increase in FTD than in AD [44.9 (28.1-68.6) vs. 21.9 (17.0-27.9) pg/ml, p<0.001]. Conversely, plasma p-tau and GFAP levels were significantly higher in the AD than in FTD [3.2 (2.4-4.3) vs. 1.1 (0.7-1.6) pg/ml, p<0.001; 404.7 (279.7-503.0) vs. 198.2 (143.9-316.8) pg/ml, p<0.001]. GFAP also allowed discriminating disease groups from HC. In the distinction between FTD and AD, plasma p-tau showed better accuracy (AUC 0.964) than NfL (AUC 0.791) and GFAP (AUC 0.818). In DLB and CBS, CSF amyloid positive (A+) subjects had higher plasma p-tau181 and GFAP levels than A- individuals.Conclusions. In a clinical setting, we confirm the high diagnostic value of plasma p-tau181 for distinguishing FTD from AD, and plasma NfL for discriminating degenerative dementias from HC. Plasma GFAP alone combines the value of distinguishing both AD from FTD and neurodegenerative dementias from HC, but with a lower accuracy than p-tau181 and NfL. In CBS and DLB, both plasma ptau181 and GFAP levels are significantly influenced by amyloid co-pathology.
Delocalized Photonic Deep Learning on the Internet's Edge
Authors: Sludds Alexander , Bandyopadhyay Saumil , Chen Zaijun , Zhong Zhizhen , Cochrane Jared , Bernstein Liane , Bunandar Darius , Dixon P. Ben , Hamilton Scott , Streshinsky Matthew , Novack Ari , Baehr-Jones Tom , Hochberg Michael , Ghobadi Manya , Hamerly Ryan , Englund Dirk 
Published: April 2022

Abstract
Advances in deep neural networks (DNNs) are transforming science and technology. However, the increasing computational demands of the most powerful DNNs limit deployment on low-power devices, such as smartphones and sensors – and this trend is accelerated by the simultaneous move towards Internet-of-Things (IoT) devices. Numerous efforts are underway to lower power consumption, but a fundamental bottleneck remains due to energy consumption in matrix algebra, even for analog approaches including neuromorphic, analog memory and photonic meshes. Here we introduce and demonstrate a new approach that sharply reduces energy required for matrix algebra by doing away with weight memory access on edge devices, enabling orders of magnitude energy and latency reduction. At the core of our approach is a new concept that decentralizes the DNN for delocalized, optically accelerated matrix algebra on edge devices. Using a silicon photonic smart transceiver, we demonstrate experimentally that this scheme, termed Netcast, dramatically reduces energy consumption. We demonstrate operation in a photon-starved environment with 40 aJ/multiply of optical energy for 98.8% accurate image recognition and <1 photon/multiply using single photon detectors. Furthermore, we show realistic deployment of our system, classifying images with 3 THz of bandwidth over 86 km of deployed optical fiber in a Boston-area fiber network. Our approach enables computing on a new generation of edge devices with speeds comparable to modern digital electronics and power consumption that is orders of magnitude lower.
Estimated health-related physical fitness in Taiwan and itsimplications for body mass index distribution and overweight/obesity risk: Results from the Taiwan Scientific Physical Fitness Testing Program
Authors: Chen Yun-Tsung , Lee Po-Fu , Hung Chang-Tsen , Lin Chi-Fang , Hsu Chen-Te , Lin Yi-Tien , Lin Hsueh-Yi , Ho Chien-Chang 
Published: April 2022

Abstract
Background: Health-related physical fitness reduces the risk of chronic disease, promotes quality of life and has enormous economic benefits considering the global health care costs resulting from obesity. However, relatively limited information is available regarding the dose–response relationship between health-related physical fitness and obesity risk. This study aimed to determine the associations of health-related physical fitness with body mass index (BMI) distribution and overweight/obesity risk among adults aged 23-64 years in Taiwan.Methods: We conducted a cross-sectional study and reviewed the data derived from the Scientific Physical Fitness Testing Program, Sports Administration, Ministry of Education in Taiwan. Responses from 16,939 participants (7,761 men; 9,178 women) aged 23-64 years from the database were collected in this study. Each participant completed a series of health-related physical fitness measurements, including cardiorespiratory fitness (3-min progressive knee-up and step [3MPKS] test), muscular fitness (hand grip strength), and flexibility (sit-and-reach test). Anthropometric measurements included body height, weight, and BMI. The quartiles of health-related physical fitness results were identified as the dependent variable in the multiple linear and multiple logistic regression analysis to determine the associations of the health-related physical fitness measurements with the BMI distribution and the overweight/obesity risk as well as the dose–response relationship.Results: The 3MPKS test and relative hand grip strength were significantly negatively associated with BMI and overweight/obesity risk with a dose–response relationship in both men and women. However, the sit-and-reach test was partially related to BMI and overweight/obesity risk in adults.Conclusions: Higher levels of the 3MPKS test and relative grip strength were associated with lower BMI and overweight/obesity risk in both sexes. Cardiorespiratory fitness and muscular fitness were effective predictors of BMI distribution and overweight/obesity risk in Taiwanese adults.
ERP Staff versus AI Recruitment with Employment Real-Time Big Data
Authors: Sun Zhaohao , Strang Kenneth David 
Published: April 2022

Abstract
The purpose of this study was to compare the performance of recruiters and an artificial intelligence (AI) program for processing internet employment big data in the enterprise resources planning (ERP) function. Previous AI implementations were discriminatory. Thus, the research question was: Could ERP staff perform better than AI in selecting the best candidate from internet employment real-time big data. A quasi-experiment was created using primary data. Job criteria were developed using machine learning to identify key skills from existing staff in a case study company. The skills were transformed into hiring criteria and a job description. AI software and a random sample of ERP recruiters assessed the same internet-based real-time big data. The results were compared between the ERP staff and AI using ANOVA followed by post-hoc Tukey. Contrary to the research question, AI out-performed ERP staff. The proposed approach might facilitate the research and development of big data, data analytics, artificial intelligence, and human resource management.