bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of terpenoids in attenuating pulmonary edema in acute lung injury: A meta-analysis of animal studies
Authors: Wang Shuai , Luo Sean X. , Jie Jing , Li Dan , Liu Han , Song Lei 
Published: August 2022

Background: The clinical efficiency of terpenoids in treating human acute lung injury (ALI) is yet to be determined. The lipopolysaccharide-induced rat model of ALI is a well-established and widely used experimental model for studying terpenoids’ effects on ALI. Using a systematic review and meta-analysis, the therapeutic efficiency of terpenoid administration on the lung wet-to-dry weight ratio in rats was investigated.Methods: Using the Cochrane Library, Embase, and PubMed databases, a comprehensive literature search for studies evaluating the therapeutic efficacy of terpenoids on ALI in rats was conducted. The lung wet-to-dry weight ratio was extracted as the main outcome. The quality of the included studies was assessed using the Systematic Review Center for Laboratory Animal Experimentation’s risk of bias tool.Results: In total, 16 studies were included in this meta-analysis. In general, terpenoids significantly lowered the lung wet-to-dry weight ratio when compared with the control vehicle (p = 0.0002; standardized mean difference (SMD): −0.16; 95% confidence interval (CI): −0.24, −0.08). Subgroup analysis revealed that low dose (≤10 μmol/kg) (p &lt; 0.0001; SMD: −0.68; 95% CI: −1.02, −0.34), intraperitoneal injection (p = 0.0002; SMD: −0.43; 95% CI: −0.66, −0.20), diterpenoid (p = 0.004; SMD: −0.13; 95% CI: −0.23, −0.04), and triterpenoid (p = 0.04; SMD: −0.28; 95% CI: −0.54, −0.01) significantly lowered the lung wet-to-dry weight ratio when compared with the control vehicle.Conclusion: A low dose of diterpenoid and triterpenoid administered intraperitoneally is effective in alleviating ALI. This systematic review and meta-analysis provides a valuable mirror for clinical research aiming at the advancement of terpenoids for preventive and therapeutic use.Systematic Review Registration: CRD42022326779
Association of LEPTIN and other inflammatory markers with preeclampsia: A systematic review
Authors: Veiga Eduardo Carvalho de Arruda , Korkes Henri Augusto , Salomão Karina Bezerra , Cavalli Ricardo Carvalho 
Published: August 2022

Background: Preeclampsia is a serious pregnancy complication that affects 5%–10% of the obstetric population.Objective: To study inflammatory markers associated with preeclampsia.Search Strategy: Searches of articles on the topic published over a 10-year period (2009–2019) were performed in three databases (PubMed, Cochrane, and Embase) using the keywords preeclampsia and inflammatory markers. The PubMed search using 10 years and humans as filters retrieved 124 articles. Using an advanced search strategy, 0 articles were identified in Embase and 10 articles in Cochrane. After screening and eligibility assessment, 13 articles were included in the systematic review and meta-analysis. Meta-analysis and quality assessment of the studies were performed using the Review Manager 5.3 program.Results: For meta-analysis, women with preeclampsia were compared to control women, i.e., pregnancies without arterial hypertension. Leptin levels were significantly higher (p &lt; 0.0002) in women with preeclampsia compared to controls. Total cholesterol was also significantly elevated in women with preeclampsia (p &lt; 0.0001). There was no significant difference in HDL between groups, but women with preeclampsia had significantly increased LDL (p &lt; 0.01). The same was observed for triglycerides, which were significantly increased in women with preeclampsia (p &lt; 0.04) compared to controls. Analysis of TNF-alpha, an important inflammatory marker, showed higher levels in women with preeclampsia (p &lt; 0.03) compared to controls. The same was observed for another important inflammatory marker, interleukin 6, which was significantly increased in women with preeclampsia (p &lt; 0.0002). There was a significant increase of C-reactive protein in women with preeclampsia (p &lt; 0.003) compared to controls.Conclusion: Women with preeclampsia have increased levels of inflammatory markers compared to control women.
Epistemic trust and personality functioning mediate the association between adverse childhood experiences and posttraumatic stress disorder and complex posttraumatic stress disorder in adulthood
Authors: Kampling Hanna , Kruse Johannes , Lampe Astrid , Nolte Tobias , Hettich Nora , Brähler Elmar , Sachser Cedric , Fegert Jörg M. , Gingelmaier Stephan , Fonagy Peter , Krakau Lina , Zara Sandra , Riedl David 
Published: August 2022

BackgroundAdverse childhood experiences (ACEs) are associated with posttraumatic and complex posttraumatic stress disorder symptoms in adulthood (PTSD/cPTSD), as well as reduced epistemic trust (trust in the authenticity and personal relevance of interpersonally transmitted information) and impaired personality functioning. The present work aims to investigate the predictive value of epistemic trust—the capacity for social learning—on the mediating effect of personality functioning in the association of ACEs and PTSD/cPTSD.MethodsWe conducted structural equation modeling (SEM) based on representative data of the German population (N = 2,004). Personality functioning (OPD-SQS) was applied as a mediator between ACEs and PTSD/cPTSD (ITQ), while epistemic trust (ETMCQ) was added as predictor for OPD-SQS. TLI, CFI, and RMSEA (95%-CI) determined the models’ fit.ResultsN = 477 (23.8%) participants reported at least one ACE and n = 218 (10.9%) reported ≥4 ACEs. Fit indices were good for both PTSD (TLI = 0.96; CFI = 0.99; RMSEA = 0.06; 95%CI: 0.041–0.078) and cPTSD (TLI = 0.96; CFI = 0.99; RMSEA = 0.06; 95%CI: 0.043–0.081). ACEs were significantly associated with cPTSD (β = 0.44, p &lt; 0.001) and PTSD (β = 0.29, p &lt; 0.001), explaining 20 and 8% of its variance. Adding personality functioning as a mediator increased the explained variance of cPTSD and PTSD to 47 and 19% while the direct association between ACEs and cPTSD/PTSD decreased (β = 0.21/β = 0.17), thus, indicating a partial mediation. Including epistemic trust substantially increased the explained variance for personality functioning (41%) compared to ACEs as a single predictor (16%).ConclusionWe add to previous research emphasizing the association between ACEs and PTSD/cPTSD symptoms. Offering insights on underlying mechanisms, we show that epistemic trust and personality functioning are relevant mediators. Since both are modifiable by psychotherapy, knowledge about the role of these constructs can inform research on psychotherapeutic interventions and prevention.
Post-traumatic growth trajectories among frontline healthcare workers during the COVID-19 pandemic: A three-wave follow-up study in mainland China
Authors: Yan Zhang , Wenbin Jiang , Bohan Lv , Qian Wu , Qianqian Li , Ruting Gu , Silong Gao , Miao Tuo , Huanting Li , Lili Wei 
Published: August 2022

ObjectivesThe COVID-19 pandemic has taken a significant toll on people worldwide for more than 2 years. Previous studies have highlighted the negative effects of COVID-19 on the mental health of healthcare workers (HCWs) more than the positive changes, such as post-traumatic growth (PTG). Furthermore, most previous studies were cross-sectional surveys without follow-ups. This study draws on PTG follow-up during the COVID-19 outbreak at 12-month intervals for 2 years since 2020. The trajectories and baseline predictors were described.MethodsA convenience sampling method was used to recruit frontline nurses or doctors at the COVID-19-designated hospital who were eligible for this study. A total of 565 HCWs completed the 2 years follow-up and were used for final data analysis. The latent growth mixture models (GMM) was used to identify subgroups of participants with different PTG trajectories. Multinomial logistic regression model was used to find predictors among sociodemographic characteristics and resilience at baseline.ResultsFour trajectory PTG types among HCWs were identified: ‘Persistent, “Steady increase”, “High with drop”, and “Fluctuated rise.” Comparing the “Persistent low” type, the other three categories were all associated with older age, higher education. Furthermore, “Persistent low” was also negatively associated with resilience at baseline.ConclusionThe PTG of HCWs with different characteristics showed different trends over time. It is necessary to increase the measure frequency to understand the PTG status in different times. Improving HCW’s resilience could help improve staff PTG.
The relations between mental well-being and burnout in medical staff during the COVID-19 pandemic: A network analysis
Authors: Chen Chen , Li Fengzhan , Liu Chang , Li Kuiliang , Yang Qun , Ren Lei 
Published: August 2022

BackgroundAlthough poor mental well-being (MW) has been documented among individuals experiencing burnout during the coronavirus-19 (COVID-19) pandemic, little is known about the complex interrelationship between different components of MW and burnout. This study investigates this relationship among medical staff during the COVID-19 pandemic through network analysis.MethodsA total of 420 medical staff were recruited for this study. Components of MW were measured by the 14-item Warwick-Edinburgh Mental Well-being Scale (WEMWBS), and components of burnout were measured by a 15-item Maslach Burnout Inventory-General Survey (MBI-GS) Questionnaire. Network structure was constructed via network analysis. Bridge variables were identified via the bridge centrality index.ResultsThe edges across two communities (i.e., MW community and burnout community) are almost negative, such as edge MW2 (“Useful”) – B14 (“Worthwhile”) and edge MW1 (“Optimistic about future”) – B13 (“Happy”). The edges within each community are nearly positive. In the MW community, components MW1 (“Optimistic about future”) and MW6 (“Dealing with problems”) have the lowest bridge centrality. And in the community of burnout, components B13 (“Happy”) and B14 (“Worthwhile”) have the lowest bridge expected influence.ConclusionWe present the first study to apply the network approach to model the potential pathways between distinct components of MW and burnout. Our findings suggest that promoting optimistic attitudes and problem-solving skills may help reduce burnout among medical staff during the pandemic.
Research on older people's health information search behavior based on risk perception in social networks—A case study in China during COVID-19
Authors: Zhang Chi , Liao Wei Fang , Ma Yi Ming , Liang Chang Yong 
Published: August 2022

ObjectiveCOVID-19 has caused great loss of human life and livelihoods. The dissemination of health information in online social networks increased during the pandemic's quarantine. Older people are the most vulnerable group in sudden public health emergencies, and they have the disadvantage of infection rates and online search for health information. This study explores the relationship between the health risk perception and health information search behavior of older people in social networks, to help them make better use of the positive role of social networks in public health emergencies.MethodBased on the Risk Information Search and Processing model, and in the specific context of COVID-19, this study redefines health risk perception as a second-order construct of four first-order factors (perceived probability, perceived severity, perceived controllability, and perceived familiarity), and constructs a research model of the health risk perception and health information search behavior of older people. An online survey of people over 55 years old was conducted through convenience sampling in China from February 2020 to March 2020.ResultsA total of 646 older adults completed the survey. The structural equation model showed that health risk perception is a second-order factor (H1), that health risk perception has significant positive effects on health information search behavior (H2: β = 0.470, T = 11.577, P &lt; 0.001), and that health risk perception has significant positive effects on affective response (H3: β = 0.536, T = 17.356, P &lt; 0.001). In addition, affective response has a significant positive mediating effect on information sufficiency (H4: β = 0.435, T = 12.231, P &lt; 0.001), and information sufficiency has a significant positive mediating effect on health information search behavior (H5: β = 0.136, T = 3.081, P = 0.002).ConclusionThe study results indicate that the health risk perception of older people during the COVID-19 outbreak not only directly affected their health information search behavior, but also had an indirect impact on their health information search behavior by affecting affective response and information sufficiency.
Individualized total laparoscopic surgery based on 3D remodeling for portal hypertension: A single surgical team experience
Authors: Jikai Yin , Dong Wang , Li Zhang , Rui Dong , Tao Yang , Bo Huang , Yibo Sun , Shixiong Lei , Qiangshan Bai , Jianguo Lu 
Published: August 2022

Background and aimsPortal hypertension (PHT) is common in end-stage cirrhosis, and variceal bleeding is the main complication associated with mortality. Surgery is usually performed in patients with PHT with a high risk of variceal bleeding in China. This study aimed to introduce an individualized and precise total laparoscopic surgical procedure based on 3D remodeling for PHT.MethodsFrom March 2013 to December 2018, 146 patients with cirrhotic PHT underwent a laparoscopic surgical procedure in our department. An individualized 3D remodeling evaluation was carried out for surgical planning.ResultsThe operation time was 319.96 ± 91.53 min. Eight of 146 patients were converted to open surgery. Acute portal vein system thrombosis occurred in 10 patients (6.85%). During the first year, 11 patients (8.15%) experienced rebleeding and two (1.48%) died. 18 patients (13.33%) experienced rebleeding and three died, giving a 3-year mortality rate of 3.66%. Compared with preoperatively, the portal vein showed significant postoperative decreases in diameter, flow velocity, and flow amount, while the hepatic artery showed significant postoperative increases in diameter, flow velocity, and flow amount. A 3D liver volume evaluation found that 19 of 21 patients had a significantly increased liver volume postoperatively, and a significantly decreased MELD score.ConclusionThis retrospective study introduced a safe, feasible, and effective individualized surgical procedure. Our results show that this surgical treatment may not only act as an effective symptomatic treatment for PHT to prevent esophageal and gastric hemorrhage, but also as an etiological treatment to increase liver function and long-term survival.
Seasonal Variation of Aromatic Plants under Cultivation Conditions
Authors: Stefanakis Michalis K. , Papaioannou Charikleia , Lianopoulou Vaia , Philotheou-Panou Eleni , Giannakoula Anastasia E. , Lazari Diamanto M. 
Published: August 2022

In this study, five plant species, members of the Lamiaceae family, namely Salvia officinalis L., Salvia rosmarinus Spenn, Mentha × piperita L., Mentha spicata L. and Origanum vulgare subsp. hirtum (Link) Ietswaart, were studied for the influence of harvesting time on the herb crop yield, the volatile compounds (EOs) content/yield and their chemical composition. EOs were isolated by means of hydro-distillation from different plant parts at different growth stages. Their components were analyzed by gas chromatography coupled with mass spectrometry (GC-MS). The highest yields of EOs were obtained at the full flowering stage and important changes were observed in their composition. The fluctuations in the percentage composition of the major compounds in the EOs, throughout harvesting time, were observed at camphor/α-thujone for S. officinalis, camphor/1,8-cineole for S. rosmarinus, linalool/linalyl acetate and carvone/limonene for M. × piperita and M. spicata, respectively. The chemotype of O. vulgare subsp. hirtum was identified as carvacrol. The optimization of harvesting time could lead to increased crop production and better EOs quality control, with numerous industrial benefits upon the commercial production of such products.
Nanoarray-Embedded Hierarchical Surfaces for Highly Durable Dropwise Condensation
Authors: Hu Yue , Jiang Kaili , Liew Kim Meow , Zhang Lu-Wen 
Published: August 2022

Durable dropwise condensation of saturated vapor is of significance for heat transfer and energy saving in extensive industrial applications. While numerous superhydrophobic surfaces can promote steam condensation, maintaining discrete microdroplets on surfaces without the formation of a flooded filmwise condensation at high subcooling remains challenging. Here, we report the development of carbon nanotube array-embedded hierarchical composite surfaces that enable ultra-durable dropwise condensation under a wide range of subcooling (

Δ

T

sub

=
8

K
–
38

K

), which outperforms existing nanowire surfaces. This performance stems from the combined strategies of the hydrophobic nanostructures that allow efficient surface renewal and the patterned hydrophilic micro frames that protect the nanostructures and also accelerate droplet nucleation. The synergistic effects of the composite design ensure sustained Cassie wetting mode and capillarity-governed droplet mobility (

Bond

number
<
0.055

) as well as the large specific volume of condensed droplets, which contributes to the enhanced condensation heat transfer. Our design provides a feasible alternative for efficiently transferring heat in a vapor environment with relatively high temperatures through the tunable multiscale morphology.
An optical measurement method for nanosecond impulse signal monitoring of partial discharge based on the Fabry–Perot interferometer sensing system
Authors: Zhang Jiawei , Wang Li , Chen Junhui , Takao Matsumoto , Diaham Sombel , Song Chen 
Published: August 2022

Abstract
Partial discharge (PD) detection in high-voltage power equipment is significant as it provides the earliest information on the degradation characteristics. A fiber-optic Fabry–Perot (F–P) sensor based on a charge-coupled probe is designed to detect PD signals under impulse voltage. When the PD signal acts on the probe, the potential difference induced by the probe leads to the deformation of the piezoelectric diaphragm, which further results in the change of light intensity signal. Thus, PD detection could be realized by converting the light intensity signal into a voltage signal. In this study, the discharge impulse signal under various voltage frequencies (50 Hz, 5 kHz, 10 kHz) has been monitored by the F–P sensor and the ultrahigh-frequency (UHF) antenna. Compared with the UHF antenna, the average sensitivity of PD signals detected by the F–P sensor is increased by 17.2%. It is of great significance for online monitoring of the insulation performance of power equipment. Moreover, the F–P sensor has powerful potential for applications such as electrostatic monitoring in aerospace, the petrochemical industry, and meteorological forecasting.
Sub-second multi-energy X-ray tomography using a multi-beam optical system and detector
Authors: Voegeli Wolfgang , Shirasawa Tetsuroh , Arakawa Etsuo , Kajiwara Kentaro , Liang Xiaoyu , Yashiro Wataru 
Published: August 2022

Abstract
A setup for fast multi-energy X-ray tomography is reported. Projection images of a sample using X-ray beams with energies below and above an absorption edge of an element of interest were recorded simultaneously with a multi-beam detector. The sample was rotated to obtain a data set for tomography. In a proof-of-principle multi-energy tomography experiment with a measurement time of 0.25 s, the neighboring elements Ag and Pd could be clearly distinguished.
Scintillation property of undoped NaI transparent ceramics
Authors: Yoshikawa Yuta , Kato Takumi , Nakauchi Daisuke , Kawaguchi Noriaki , Yanagida Takayuki 
Published: August 2022

Abstract
In this study, NaI transparent ceramics were synthesized by the spark plasma sintering method, also optical and scintillation properties were investigated. To evaluate the potential of the transparent ceramics, a NaI single crystal was also prepared by the vertical Bridgman–Stockbarger method. The diffuse transmittance of the transparent ceramic fabricated at 470 °C was equivalent to that of the single crystal. All the samples showed scintillation peaking at 320 nm due to self-trapped exciton. In addition, scintillation peaks ascribed from lattice defects were detected at 450 nm for the transparent ceramics and 540 nm for the single crystal. The scintillation decay time constants of the transparent ceramic fabricated at 440 °C were 5.7, 18, and 189 ns. The light yield of the transparent ceramic turned out to be 910 photons MeV−1 and was two-thirds of the single crystal.
Phase-controllable multi-laser system with coaxially combined near-infrared and subcycle mid-infrared and THz pulsed beams
Authors: Arashida Yusuke , Umeda Naoki , Mogi Hiroyuki , Ishikawa Masashi , Hatanaka Akira , Takeuchi Osamu , Yoshida Shoji , Shigekawa Hidemi 
Published: August 2022

Abstract
With the progress of infrared high-intensity pulse technology, the ultrafast control of electronic states has been attracting considerable attention. Most elementary excitations of solids have resonance energy in the mid-infrared (MIR) frequency domain. Therefore, to understand these dynamics in detail and open up new possibilities, new technological innovations are desired. In this study, we have developed a system that combines 8 fs near-infrared pulsed light with carrier envelope phase-controllable subcycle MIR and THz pulsed lights. This technology has produced a new method that enables the analysis of phase-sensitive phenomena in the near-infrared to far-infrared region.
KORELASI MOTIVASI DIRI DENGAN PERILAKU KONTROL TEKANAN DARAH PENDERITA HIPERTENSI DI UPTD PUSKESMAS KERAMBITAN I
Authors: Sarah Kartika Wulandari , Negara IGN Made Kusuma , Dewi Ni Luh Putu Sri Utami 
Published: August 2022

Latar Belakang: Hipertensi sebagai salah satu gangguan kardiovaskuler dengan komplikasi berupa serangan jantung, stroke dan penyakit ginjal dengan angka kejadian yang terus meningkat. Ketidakpatuhan penderita dalam kontrol tekanan darah akan memicu terjadinya kekambuhan dan komplikasi. Tujuan: mengetahui korelasi antara motivasi diri dengan perilaku kontrol tekanan darah pada penderita hipertensi di Unit Pelaksana Teknis Daerah (UPTD) Puskesmas Kerambitan I. Metode Penelitian: penelitian ini menggunakan desain analitik korelasi dengan pendekatan cross sectional. Pemilihan sampel penelitian menggunakan Non probability sampling dengan metode pengambilan sampel consecutive sampling. Pengambilan data dilakukan secara luar jaringan (offline) dengan menerapkan protocol kesehatan secara ketat. Analisa data menggunakan uji statistik Spearman’s rho. Hasil penelitian: Hasil dari 125 responden, sebagian besar responden memiliki motivasi yang kurang yaitu sebanyak 81orang (64,8%) dan sebagian besar responden memiliki perilaku kontrol kurang yaitu sebanyak 52 orang (41,6%). Hasil uji statistik didapatkan nilai p value 0,000 < α 0,05, nilai koefisien korelasi pada penelitian ini menunjukkan kekuatan korelasi antar kedua variabel dalam kategori sangat kuat yaitu 0,870 dengan arah korelasi positif. Simpulan: terdapat hubungan yang signifikan antara motivasi diri dengan perilaku kontrol tekanan darah pada penderita hipertensi di UPTD Puskesmas Kerambitan I.