bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dietary supplementation with Pediococcus pentosaceus enhances the innate immune response in and promotes growth of Litopenaeus vannamei shrimp
Authors: Le Bao , Kim Dong‐Geun , Phuoc Nguyen Ngoc , Linh Nguyen Thi Hue , Yang Seung‐Hwan 
Published: June 2022

AbstractTo reach the sustainable development goals on health management in Litopenaeus vannamei shrimp culture, Pediococcus pentosaceus AB01 was supplemented in shrimp diet. In this study, the control diet and three experimental diets containing P. pentosaceus AB01 (108, 109, 1010 CFU/g) were separately introduced to L. vannamei for a 28 days feeding trial. After the feeding trial, percent weight gain, feeding efficiency, and feed conversion ratio (FCR) were significantly elevated in L. vannamei administered with P. pentosaceus AB01 at 109 and 1010 colony‐forming unit (CFU)/g. Protease, amylase, and trypsin were found at higher levels in the probiotic‐supplied groups. The feeding of shrimps with P. pentosaceus AB01 significantly increased innate immune response and levels of related biochemical parameters in the haemolymph. After the white spot syndrome virus (WSSV) challenge, supplementation of P. pentosaceus AB01 had significant positive effects (p < .05) on survival rate, compared to that of the control diet. The higher resistance of L. vannamei to WSSV might have been due to alterations in the gut microbiome composition and upregulation of the Toll‐Like Receptor (TLR) signalling pathway. Hence, P. pentosaceus AB01 may be a promising alternative feed to promote growth rate, modulate microbiota composition, and enhance immunity in L. vannamei shrimp.
Distribution of Vibrionaceae in farmed Asian sea bass, Lates calcarifer in Thailand and their high prevalence of antimicrobial resistance
Authors: Raharjo Hartanto Mulyo , Budiyansah Hendri , Mursalim Muhammad Fadhlullah , Chokmangmeepisarn Putita , Sakulworakan Rungnapa , Madyod Sulaiman , Sewaka Mariya , Sonthi Molruedee , Debnath Partho Pratim , Elayaraja Sivaramasamy , Rung‐ruangkijkrai Tilladit , Dong Ha Thanh , Rodkhum Channarong 
Published: June 2022

AbstractThis study describes the etiological agent of Vibriosis along with its distribution and antimicrobial resistance profiles among farmed Asian sea bass (Lates calcarifer) in Thailand. The study isolated 283 Vibrionaceae from 15 Asian sea bass farms located around the provinces of the Andaman Sea and Gulf of Thailand coasts to uncover the distribution and antimicrobial resistance profiles. Bacterial identification based on a combination of the biochemical characteristics, Matrix‐assisted laser desorption/ionization‐time of flight (MALDI‐TOF) mass spectrometry (MS) analysis, and the species‐specific PCR demonstrated the predominant Vibrionaceae were Vibrio harveyi (n = 56), Photobacterium damselae (n = 35), and V. vulnificus (n = 31), respectively. According to a laboratory challenge experiment, among the six isolates, only V. harveyi was found to cause clinical signs of muscle necrosis and scale loss in Asian sea bass. Antibiotics resistance test results exhibited high resistance to antibiotics such as metronidazole (100%), streptomycin (97%), clindamycin (96%), colistin sulphate (70%) and amoxicillin (59%). Remarkably, 100% of Vibrionaceae isolates are susceptible to florfenicol. The 28 of 29 resistance profiles were multidrug resistances (MDR), with V. vulnificus having the highest MAR value (0.66). The findings of this study advise that a surveillance program, as well as preventive and control measures, be developed for Vibrionaceae to reduce production loss, pathogen proliferation, and antibiotic abuse, whereas AMR data indicate substantial health problems for aquatic animals and humans.
Combination of LF‐NMR and BP‐ANN to monitor the moisture content of rice during hot‐air drying
Authors: Wang Hongchao , Che Gang , Wan Lin , Wang Xin , Tang Hao 
Published: June 2022

AbstractIn this study, a rapid real‐time nondestructive method for detecting the moisture content of rice during hot‐air drying was investigated. Intelligent techniques of low‐field nuclear magnetic resonance (LF‐NMR) and back propagation artificial neural network (BP‐ANN) were applied to monitor the moisture content of rice. The effect of different hot‐air temperatures (35, 45, 55, and 65°C) on the moisture content and water migration within rice was studied. The results showed that the drying temperature promoted the diffusion and transfer of water within the rice, and was positively proportional to the drying rate. The binding energy of the different states of water within rice increased with the drying process, and the variation in relaxation time and peak area was consistent for each stage at different temperatures. In addition, the amount of LF‐NMR signals was used as an indicator to build a predictive model for the moisture content of rice during hot‐air drying. A BP‐ANN prediction model optimized by transfer function, training function and number of neurons was used to monitor the moisture content of rice using the amount of LF‐NMR signals of different states of water as input variables. The optimized neural network model had the excellent predictive ability with an MSE of 6.02 × 10−6 and R2 of 0.996. These results provide a reference for combining LF‐NMR and BP‐ANN in the application of intelligent online monitoring of hot‐air drying of rice.Practical ApplicationsThe monitoring of moisture content during hot‐air drying of rice is an essential parameter for optimizing the drying process. The combined approach of LF‐NMR and BP‐ANN for rapid real‐time nondestructive monitoring is well suited to hot‐air drying of rice, allowing for improved product quality and operational processes. In addition, the model developed in this study has the good predictive performance to meet the current industry and production needs, providing new research ideas and technical references for the optimization of the drying process of rice.
Optimism, lifestyle, and longevity in a racially diverse cohort of women
Authors: Koga Hayami K. , Trudel‐Fitzgerald Claudia , Lee Lewina O. , James Peter , Kroenke Candyce , Garcia Lorena , Shadyab Aladdin H. , Salmoirago‐Blotcher Elena , Manson JoAnn E. , Grodstein Francine , Kubzansky Laura D. 
Published: June 2022

AbstractBackgroundResearch has suggested optimism is associated with healthy aging and exceptional longevity, but most studies were conducted among non‐Hispanic White populations. We examined associations of optimism to longevity across racial and ethnic groups and assessed healthy lifestyle as a possible mediating pathway.MethodsParticipants from the Women's Health Initiative (N = 159,255) completed a validated measure of optimism and provided other demographic and health data at baseline. We evaluated associations of optimism with increments in lifespan using accelerated failure time models, and with likelihood of exceptional longevity (survival to age ≥90) using Poisson regression models. Causal mediation analysis explored whether lifestyle‐related factors mediated optimism‐lifespan associations.ResultsAfter covariate adjustment, the highest versus lowest optimism quartile was associated with 5.4% (95% confidence interval [CI] = 4.5, 6.4%) longer lifespan. Within racial and ethnic subgroups, these estimates were 5.1% (95%CI = 4.0, 6.1%) in non‐Hispanic White, 7.6% (95%CI = 3.6, 11.7%) in Black, 5.4% (95%CI = −0.1, 11.2%) in Hispanic/Latina, and 1.5% (95% CI = −5.0, 8.5) in Asian women. A high proportion (53%) of the women achieved exceptional longevity. Participants in the highest versus lowest optimism quartile had greater likelihood of achieving exceptional longevity (e.g., full sample risk ratio = 1.1, 95%CI = 1.1, 1.1). Lifestyle mediated 24% of the optimism‐lifespan association in the full sample, 25% in non‐Hispanic White, 10% in Black, 24% in Hispanic/Latina, and 43% in Asian women.ConclusionsHigher optimism was associated with longer lifespan and a greater likelihood of achieving exceptional longevity overall and across racial and ethnic groups. The contribution of lifestyle to these associations was modest. Optimism may promote health and longevity in diverse racial and ethnic groups. Future research should investigate these associations in less long‐lived populations.
Effects of some medicinal plant extracts on dermal papilla cells
Authors: Wisuitiprot Vanuchawan , Ingkaninan Kornkanok , Wisuitiprot Wudtichai , Srivilai Jukkarin , Chakkavittumrong Panlop , Waranuch Neti 
Published: June 2022

AbstractIntroductionMiniaturization of the hair follicles is evident on the balding scalp. Approved medications, topical minoxidil, and oral finasteride for the treatment of alopecia sometimes come with undesirable adverse effects. The study was to examine the bioactivity of medicinal plants for finding the promising source of anti‐hair loss application.MethodsTen ethanolic extracts were prepared from Acacia concina (Willd.) DC., Acanthus ebracteatus Vahl, Bridelia ovata Decne, Cleome viscosa L., Cocos nucifera L., Hibiscus subdariffla L., Oryza sativa L., Terminalia chebula Retz., Tinospora crispa (L.) Hook. f. & Thomson and cytotoxic tested on dermal papilla cells using MTT assay. The effect of the extracts on cell cycle was also determined using flow cytometry technique. Anti‐inflammatory activity was examined by determining IL‐1β inhibition in RAW 257.4 cells. In vitro study of androgenic and 5α‐reductase inhibitory activities were also determined using MTT assay and enzymatic reaction couple with liquid chromatography–mass spectrometry (LC–MS), respectively.ResultsOur results revealed that only A. ebracteatus promoted dermal papilla cell proliferation and the S and G2/M phases in cell cycle. A. ebracteatus also showed inhibitory activity against 5α‐reductase and testosterone in reducing cell viability of the dermal papilla. Moreover, A. ebracteatus extract strongly inhibited LPS‐stimulating IL‐1β production in RAW 264.7 cells in a dose‐dependent manner.ConclusionOur finding indicated that the ethanolic extract of A. ebracteatus is a promising candidate for anti‐hair loss treatment.
The rising midlife first marriage rate in the U.S.
Authors: Brown Susan L. , Lin I‐Fen , Mellencamp Kagan A. 
Published: June 2022

AbstractObjectiveThis study documented change in the midlife first marriage rate for U.S. adults aged 40–59 between 1990 and 2019 and assessed the sociodemographic correlates of midlife first marriage formation for today's women and men.BackgroundMedian ages at first marriage are at record highs for women and men, signaling that marriage may be increasingly occurring at older ages. However, first marriage formation among midlife adults remains largely overlooked.MethodData from the 1990 U.S. Vital Statistics and the 2010 and 2019 American Community Survey (ACS) were used to estimate the change in women's and men's first marriage rates across age groups, with a focus on how the rate has changed for midlife adults. Average marginal effects (AMEs) were derived from logistic regression analyses that drew on the 2019 ACS to examine associations between sociodemographic factors and midlife first marriage formation for women and men.ResultsSince 1990, the midlife first marriage rate has increased by 75% for women and 45% for men. The shares of women and men entering a first marriage who were aged 40–59 quadrupled between 1990 and 2019 (rising from 2% to 9% among women and from 3% to 12% among men). Some of the well‐established predictors of first marriage in young adulthood operated uniquely for first marriage formation in midlife.ConclusionFuture research on first marriage formation should incorporate midlife adults.
Innovation's domain: The need for a sharper yet broader focus
Authors: Raj S. P. , Athaide Gerard A. 
Published: June 2022

AbstractKahn's (2022) essay notes the growth in centers for innovation and entrepreneurship on college campuses and prompted his call for a clearer understanding and appreciation of the roles of the two phenomena. Kahn argues that while entrepreneurship focuses on new “venture” creation, innovation focuses on “offering” creation, i.e., creating new products, services, marketing methods, etc. His essay stimulated us to reflect on how the study and practice of innovation management have evolved and developed, especially in the marketing discipline. In large part, recent interest in entrepreneurship and innovation has been fueled by digital technologies (DT). These technologies have enabled entrepreneurial start‐ups as well as elevated the prominence of innovative marketing practices as a source of competitive advantage. Despite their relevance for innovations in marketing strategy formulation and execution, research on DT‐enabled marketing innovation is limited and fragmented. Against this background, this article describes the Snyder Innovation Management Center at Syracuse University's emphasis on the academic study of innovation management in a marketing context. The Center's areas of focus offer a useful starting point for a sharpened yet broader focus concerning to the study of innovation.
Effects of vegan diets on cardiometabolic health: A systematic review and meta‐analysis of randomized controlled trials
Authors: Termannsen Anne‐Ditte , Clemmensen Kim Katrine Bjerring , Thomsen Jonas Mark , Nørgaard Ole , Díaz Lars Jorge , Torekov Signe Sørensen , Quist Jonas Salling , Færch Kristine 
Published: June 2022

SummaryIn parallel with an increased focus on climate changes and carbon footprint, the interest in plant‐based diets and its potential health effects have increased over the past decade. The objective of this systematic review and meta‐analysis was to examine the effect of vegan diets (≥12 weeks) on cardiometabolic risk factors in people with overweight or type 2 diabetes. We identified 11 trials (796 participants). In comparison with control diets, vegan diets reduced body weight (−4.1 kg, 95% confidence interval (CI) −5.9 to −2.4, p < 0.001), body mass index (BMI) (−1.38 kg/m2, 95% CI −1.96 to −0.80, p < 0.001), glycated hemoglobin (HbA1c) (−0.18% points, 95% CI −0.29 to −0.07, p = 0.002), total cholesterol (−0.30 mmol/L, 95% CI −0.52 to −0.08, p = 0.007), and low‐density lipoprotein cholesterol (−0.24 mmol/L, 95% CI −0.40 to −0.07, p = 0.005). We identified no effect on blood pressure, high‐density lipoprotein cholesterol, and triglycerides. We found that adhering to vegan diets for at least 12 weeks may be effective in individuals with overweight or type 2 diabetes to induce a meaningful decrease in body weight and improve glycemia. Some of this effect may be contributed to differences in the macronutrient composition and energy intake in the vegan versus control diets. Therefore, more research is needed regarding vegan diets and cardiometabolic health.
Determinants of Complex Regional Pain Syndrome Type I among Radial Head Fracture Patients with Unilateral Arthroplasty
Authors: Wang Ye , Jiang Menglu , Dai Xu , Zhang Qin 
Published: June 2022

ObjectiveThis study aims to assess the proportions of complex regional pain syndrome type I (CRPS I) in radial head fracture patients undergoing unilateral arthroplasty and to explore associated factors.MethodsThis is a prospective observational study. From March 2016 to May 2019, a total of 221 adult patients with radial head fracture patients were included in consecutive studies and completed the 1‐year follow‐up. All patients were treated by unilateral arthroplasty. At each follow‐up visit, the visual analogue scale was used to measure patients' pain level. Occurrence of CRPS I, which was diagnosed by Budapest criteria, was the main outcome collected at baseline and the 1‐, 3‐, 6‐, and 9‐month follow‐ups. The baseline data were collected before surgery and included demographic and clinical data. Independent t‐tests and χ2 tests were used as univariate analyses to compare the baseline data of patients with and without CRPS I. Multivariate analysis (Backword‐Wald) was used to identify factors independently associated with CRPS I.ResultsThe proportion of CRPS I cases among radial head fracture patients undergoing unilateral arthroplasty was 11% (n = 24). A total of 19 (79%) patients were diagnosed with CRPS I within 1 month after surgery. Multivariable logistic regression analysis revealed that female gender (odds ratios [OR]: 1.537; 95% confidence interval [CI]: 1.138–2.072), age younger than 60 years (OR: 1.682; 95% CI: 1.246–2.267), moderate and severe Mayo Elbow Performance Score (MEPS) pain (OR: 3.229; 95% CI: 2.392–4.351) and anxiety (OR: 83.346; 95% CI: 61.752–112.320) were independently associated with CRPS I.ConclusionsThis exploratory study reported that the incidence of CRPS I developing after radial head arthroplasty was 11%. Female sex, younger age, moderate and severe MEPS pain and anxiety patients seems more likely to develop CRPS I.
Childhood cancer survival and avoided deaths in Australia, 1983–2016
Authors: Youlden Danny R. , Baade Peter D. , Moore Andrew S. , Pole Jason D. , Valery Patricia C. , Aitken Joanne F. 
Published: June 2022

AbstractBackgroundLarge improvements in childhood cancer survival have been reported over recent decades. Data from cancer registries have the advantage of providing a ‘whole of population’ approach to gauge the success of cancer control efforts.ObjectivesThe aim of this study was to investigate recent survival estimates for children diagnosed with cancer Australia and to examine the extent of changes in survival over the last 35 years. For the first time, we also estimated the number of deaths among Australian children that were potentially avoided due to improvements in survival.MethodsA retrospective, population‐based cohort study design was used. Case information was extracted from the Australian Childhood Cancer Registry for 1983–2016, with follow‐up to 31 December 2017. Eligible children were aged 0–14 with a basis of diagnosis other than autopsy or death certificate only. Five‐year relative survival was calculated using the semi‐complete cohort method for three diagnosis periods (1983–1994, 1995–2006 and 2007–2016), and changes in survival over time were assessed via flexible parametric models. Avoided deaths within 5 years for those diagnosed between 1995 and 2016 were estimated under the assumption that survival rates remained the same as for 1983–1994.ResultsOverall 5‐year survival within the study cohort (n = 20,871) increased from 72.8% between 1983 and1994 to 86.1% between 2007 and 2016, equating to an adjusted excess mortality hazard ratio of 1.82 (95% confidence interval 1.67, 1.97). Most cancers showed improvements in survival; other gliomas, hepatoblastoma and osteosarcoma were exceptions. Among children diagnosed between 1995 and 2016, 38.7% of expected deaths within 5 years of diagnosis (n = 1537 of 3970) were avoided due to temporal improvements in survival.ConclusionsSurvival for childhood cancer has continued to improve over recent years, thanks mainly to ongoing progress in treatment development combined with improved supportive care. Providing innovative measures of survival, such as avoided deaths, may assist with understanding outcome data produced by cancer registries.
Performance of predictive models of survival in horses undergoing emergency exploratory laparotomy for colic
Authors: Bishop Rebecca C. , Gutierrez‐Nibeyro Santiago D. , Stewart Matthew C. , McCoy Annette M. 
Published: June 2022

AbstractObjectiveTo evaluate previously published predictive survival models in a population of horses undergoing colic surgery in the midwestern United States.Study designRetrospective cohort study; single referral hospital.AnimalsA total of 260 horses met the inclusion criteria.MethodsMedical records of horses undergoing surgical treatment for colic were reviewed. Previously published models were applied to cohort data to predict outcome. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy for prediction of short‐term survival were calculated.ResultsSingle‐variable and multivariable models performed similarly for prediction of survival, with a mean 79% sensitivity (range: 44%–94%), 48% specificity (range: 22%–83%), 63% PPV (range: 56%–72%), 73% NPV (range: 60%–83%), and 64% accuracy (range: 59%–72%). Blood lactate ≤6 mmol/l and the colic severity score (CSS) were highly sensitive for prediction of survival; however, both had poor specificity.ConclusionSingle‐variable and multivariable predictive models did not perform as well for prediction of survival in the study cohort compared to original reports, suggesting that population‐specific factors contribute to patient survival.Clinical significancePredictive models of survival developed in one population may be less reliable when used to predict outcome in horses undergoing colic surgery from an independent population. Additional model testing and refinement using data from multiple surgical centers could be considered to improve prediction of outcome for horses undergoing laparotomy for treatment of colic.
Docencia en contexto de pandemia. En el vórtice de la injusticia social
Authors: Paz-Maldonado Eddy , Silva-Peña Ilich , Nunes-Fernandes Celia 
Published: June 2022

Este artículo explora las experiencias docentes en el contexto de la crisis sanitaria por COVID-19. El estudio se sitúa dentro de un enfoque cualitativo, bajo un diseño transversal, con una primera etapa descriptiva. Se efectuaron entrevistas episódicas semiestructuradas a seis profesoras de educación básica que laboran en escuelas urbanas y rurales en Honduras. De las entrevistas emergen cuatro dificultades que impactan en lo educativo: los problemas de alimentación, la precaria situación económica de los hogares, el apoyo de las familias y las desigualdades en acceso a la tecnología, tanto en dispositivos como en conectividad.
Study of the Running-In Period in the Twin-Disc Wear Test Using Steel From a Class C Forged Railway Wheel
Authors: Luccidi Yanna , Rezende Andrei Bavaresco , Fonseca Solange Tamara , Mei Paulo Roberto 
Published: June 2022

Abstract
The railway wheels are one of the most critical components of the train and, any problem that may arise in the wheel, can generate numerous consequences. The ability to manage friction at the wheel–rail interface currently represents one of the greatest challenges and one of the most powerful tools in railway engineering. To define the efficiency of a product for friction control, retentivity tests are performed mainly by the suppliers. However, there is no strict standardization for the tribological test performance, and some critical issues like the influence of running-in period and the necessary superficial conditions of the rolling track to apply the friction control products are neglected. Thus, the objective of this work is to conduct dry twin-disc wear tests with different number of cycles to understand the running-in period and verify the tribosystem behavior. Starting from a rolling track with a polished surface, it was noted that the roughness increased rapidly and stabilized around 1500 cycles. The coefficient of traction (COT) increased at the beginning of the tests reaching the maximum at 750 cycles, reducing the value after that, and stabilizing at a value close to 0.4 with 5000 cycles. Thus, for twin-disc tests using these conditions, it is suggesting the application of friction control products from 5000 cycles because the COT and roughness would be stabilized.