bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tracking motor and language eloquent white matter pathways with intraoperative fiber tracking versus preoperative tractography adjusted by intraoperative MRI–based elastic fusion
Authors: Zhang Wei , Ille Sebastian , Schwendner Maximilian , Wiestler Benedikt , Meyer Bernhard , Krieg Sandro M. 
Published: March 2022

OBJECTIVE
Preoperative fiber tracking (FT) enables visualization of white matter pathways. However, the intraoperative accuracy of preoperative image registration is reduced due to brain shift. Intraoperative FT is currently considered the standard of anatomical accuracy, while intraoperative imaging can also be used to correct and update preoperative data by intraoperative MRI (ioMRI)–based elastic fusion (IBEF). However, the use of intraoperative tractography is restricted due to the need for additional acquisition of diffusion imaging in addition to scanner limitations, quality factors, and setup time. Since IBEF enables compensation for brain shift and updating of preoperative FT, the aim of this study was to compare intraoperative FT with IBEF of preoperative FT.

METHODS
Preoperative MRI (pMRI) and ioMRI, both including diffusion tensor imaging (DTI) data, were acquired between February and November 2018. Anatomy-based DTI FT of the corticospinal tract (CST) and the arcuate fascicle (AF) was reconstructed at various fractional anisotropy (FA) values on pMRI and ioMRI, respectively. The intraoperative DTI FT, as a baseline tractography, was fused with original preoperative FT and IBEF-compensated FT, processes referred to as rigid fusion (RF) and elastic fusion (EF), respectively. The spatial overlap index (Dice coefficient [DICE]) and distances of surface points (average surface distance [ASD]) of fused FT before and after IBEF were analyzed and compared in operated and nonoperated hemispheres.

RESULTS
Seventeen patients with supratentorial brain tumors were analyzed. On the operated hemisphere, the overlap index of pre- and intraoperative FT of the CST by DICE significantly increased by 0.09 maximally after IBEF. A significant decrease by 0.5 mm maximally in the fused FT presented by ASD was observed. Similar improvements were found in IBEF-compensated FT, for which AF tractography on the tumor hemispheres increased by 0.03 maximally in DICE and decreased by 1.0 mm in ASD.

CONCLUSIONS
Preoperative tractography after IBEF is comparable to intraoperative tractography and can be a reliable alternative to intraoperative FT.
Evaluating the effectiveness of fine gold extraction technologies on the example of titanomagnetite beach placers of the western coast of Kamchatka
Authors: Kungurova Valentina 
Published: March 2022

The material on the gold content of coastal-marine deposits of the western coast of Kamchatka is analyzed and the resource potential is briefly characterized. A review of gold technological estimates obtained from the study of gold-bearing samples taken in promising areas of the coastal-marine strip, from the Bolshaya Vorovskaya River in the north to Cape Levashova in the south, is presented. Stock materials supplemented by our studies were used. Gold-bearing deposits with very fine (0.05-0.1 mm) and fine (0.1-1.0 mm) gold amounting to 94.6 % were tested, as well as samples with gold up to 2 mm and more in addition to fine gold The content of freely recoverable gold reached 91.9 %. In the case of significant gold reserves in placers, prospects for their commercial development open up. experiments on the enrichment of gold-bearing coastal-marine deposits of Western Kamchatka indicate the possibility of extraction of free gold and other valuable components from them. Gravity technologies and modern equipment developed by ОАО Irgiredmet and JSC ITOMAK are the most effective for their extraction. enrichment of gold-bearing formations with simultaneous extraction of several useful components from them, which is possible with the use of fluoride technology, can also become economically advantageous.
Then and Now Space: Conceptual Mapping of Time and Space through Language in William Diehl’s Primal Fear
Authors: Waqar Noureen , Ali Zulfiqar 
Published: March 2022

Language aids in the conceptual mapping between time and space. Furthermore, an individual holds both the real and the imaginary world in their memory and tries to make sense of it through the help of language. Language plays a significant role in mapping the abstract concepts rooted in the real world and stored in the human mind. The current study was aimed at tracing input and blended spaces in the selected text. It also analyzed the conceptual mapping between time and space through language and examined its significance in the selected character, named Aaron Stampler, in a novel titled ‘Primal Fear’. The study adds to the existing knowledge in the field of cognitive linguistics by tracing the connection between past and present mental spaces inside the human memory. It also highlights the mechanisms of then (past) and now (present) in mapping mental spaces through language. The current study is based on a conceptual framework designed by blending two theories: Conceptual Integration Theory and Here and Now Space. The analysis of the selected text revealed that conceptual mapping between then and now spaces connects the memories of the past with the present. An individual collects data from their surrounding and stores it in the form of language, to be used when required. The study concluded that mental concepts are mapped between time and space through the relatedness of their subject matter, which is traced with the help of language. The findings of this research may aid in investigating the language used in interrogating criminals, cross-questioning them, as well as dissecting their psychiatric sessions.
Keywords: conceptual mapping, here and now space, input space, mental spaces
Comparación de los resultados del Exani-II con el desempeño de los estudiantes cinco años después.
Authors: Torres Soto A. , Torres Soto M.D. , Ponce de León E.E. 
Published: March 2022

En este trabajo se reportan los hallazgos del análisis de un grupo de 46 estudiantes, transcurridos cinco años de la presentación de la evaluación estandarizada EXANI-II aplicada en la ciudad de Aguascalientes en el año 2013. Inicialmente se agrupó a los jóvenes en una de tres categorías de acuerdo a su situación académica actual (alumno regular, alumno rezagado o alumno desertor). Posteriormente se analizaron los resultados que cada uno de los jóvenes obtuvo con la intención de establecer si existe relación entre los resultados obtenidos en las diferentes áreas del examen y su situación académica actual. Una vez realizadas las pruebas estadísticas se encontró que a pesar de que parecía existir cierta relación entre los resultados de matemáticas y español con la situación actual, no existe evidencia estadística que respalde esta hipótesis; así es que los resultados del Exani-II, no poseen poder de predicción a largo plazo.
In this paper, we report the findings of the analysis of a group of 46 students, five years after the presentation of the standardized evaluation EXANI-II applied in the city of Aguascalientes in 2013. Initially youths were grouped in three ranks according to their current academic situation (regular student, irregular student or deserter student). Subsequently the results those students obtained of EXANI-II were analyzed looking for relationship with their current academic situation. Once statistical tests were performed, it was found that even though was a relationship between math and Spanish results with the current academic situation, there is not statistical evidence to suggest that; so, Exani-II results have not power of long-term prediction.
The effect of static passive stretching on a bench press, in one maximum repetition test performance, is independent of the level of flexibility
Authors: Lima Vanessa Da Silva , Iara Diniz Iara Bezerra , Lopes Jonathan Moreira 
Published: March 2022

Objective: The aim of this study was to investigate at different levels of flexibility the influence of static passive stretching on bench press one maximum repetition test.
Method: Eleven men (26.09 ± 4.2 years, 81.69 ± 13.94 kg, 1.70 ± 0.05 m) were evaluated in flexibility using Flexitest and goniometry test classified according to their flexibility levels (small and upper middle levels) and joint range of motion (deficit levels), as well as performed the one maximum repetition test in the following experimental protocols: without previous stretching and with stretching 10, 20 and 60 seconds before the test.
Results: The results indicate that 64% demonstrated a low level of flexibility and 36% with a higher average level. In both, there was no significant difference in load: A0s (72.43 ± 21.10Kg vs 66.25 ± 19.02Kg); A10s (72.29 ± 20.25Kg vs 67.25 ± 20.35Kg); A20s (73.43 ± 20.78Kg vs 67.75 ± 18.23Kg) and A60s (73.29 ± 19.35Kg vs 68 ± 19.25Kg). ANOVA for repeated measures showed that no significantly different the maximum strength between groups the protocols of static passive stretching tested.
Conclusion: It was concluded that passive static stretching times lower than 60 seconds, in accordance with the current recommendations, do not interfere in the neuromuscular performance of men in the one maximum repetition test, in the bench press independent of their level of flexibility.
Nível de atividade física entre usuários de substâncias psicoativas
Authors: Matias Guilherme Henrique de Lima , Fonseca Rômulo Maia Carlos 
Published: March 2022

Objetivo: Este estudo verificou o nível de atividade física entre usuários de substâncias psicoativas.
Método: Estudo transversal, realizado nos Centros de Atenção Psicossocial Álcool e Outras Drogas do município de Recife (Brasil). Participaram 160 indivíduos com idade 44.09±12.46 anos. Os participantes foram entrevistados por meio do questionário Global physical active questionnaire. Foi aplicado o teste Qui-quadrado de independência para verificar associação entre nível de atividade física e tipo de substância psicoativa utilizada, nível de instrução, raça/cor, sexo e tipo de moradia sendo aceito um p<0.05 como significativo.
Resultados: Os resultados mostraram que 51.9% dos usuários de substâncias psicoativas são fisicamente inativos. Houve associação nos domínios raça/cor da pele (p=0.039) e nível de instrução (p=0.002) com relação ao nível de atividade física.
Conclusão: A partir destes dados será possível estabelecer os grupos que necessitam de maior apoio para promover estímulo à prática de exercício físico.
Faktor yang Mempengaruhi Keberhasilan Pengobatan Orang Dengan Gangguan Jiwa (ODGJ)
Authors: Oktaviana Meli , Ratnawati Riska 
Published: March 2022

Gangguan jiwa merupakan penyakit kronis yang membutuhkan proses panjang dalam penyembuhannya. Berdasarkan data daftar peserta ODGJ Desa Sukosari dari 28 pasien terdapat 6 orang yang sembuh. Artinya tingkat kesembuhan ODGJ di Desa Sukosari adalah 21%. Sedangkan target dari Puskesmas Sukosari mengenai ODGJ yang minum obat yaitu 90%. Penelitian ini bertujuan untuk mendeskripsikan terkait ekonomi keluarga, dukungan keluarga dan dukungan petugas kesehatan yang dapat mempengaruhi keberhasilan pengobatan ODGJ. Metode yang digunakan dalam penelitian ini adalah kualitatif. Penentuan subjek penelitian berdasarkan teknik Purposive dengan jumlah subjek penelitian sebanyak 6 keluarga. Pengumpulan data melalui wawancara mendalam dan dokumentasi. Hasil penelitian didapatkan bahwa mayoritas keluarga memberikan dukungan berupa dukungan secara emosional (empati dan peduli), instrumental (bantuan biaya, bantuan jasa, bantuan waktu) dan pemantauan minum obat kepada anggota keluarga yang mengalami gangguan jiwa. Mayoritas keluarga mendapatkan dukungan dari petugas kesehatan meliputi kunjungan rutin untuk dilakukan penyuntikan dan pemberian obat, serta pemantauan kepada pasien. Kesimpulan dalam penelitian ini yaitu adanya dukungan keluarga dan dukungan petugas kesehatan kepada ODGJ dapat memberikan dampak positif yang ditunjukkan dengan adanya keberhasilan pengobatan sehingga ODGJ mencapai tingkat kesembuhan. Dari penelitian ini, saran yang disampaikan adalah penelitian ini dapat dijadikan sebagai referensi peneliti selanjutnya untuk lebih mengembangkan penelitian ini.
Penguatan Peran Pemerintah Desa Cileles dalam Membangun Usaha Mikro Kecil (UMK)
Authors: Mulyana Mulyana , Nurrahman Agung , Abdurohim Abdurohim 
Published: March 2022

Rendahnya peran Pemerintah Desa Cileles dalam mendampingi pelaku UMK menjalankan usahanya menjadi fokus permasalahan yang diangkat dalam kegiatan pengabdian masyarakat. Tujuan dari kegiatan pengabdian masyarakat adalah untuk memperkuat peran dari Pemerintah Desa di Desa Cileles dalammembangun UMK di Desa Cileles. Adapun metode dalam kegiatan pengabdian kepada masyarakat (PKM) antara lain menggunakan metode sosialisasi, penyampaian materi dan dialog terbuka bersama Pemerintah Desa Cileles, anggota Badan Permusyawaratan Desa (BPD), tokoh RT/RW dan masyarakat pelaku UMK di Desa Cileles. Hasil dari kegiatan pengabdian adalah: 1) adanya output berupa penguatan peran Pemerintah Desa Cileles sebagai regulator dan menerbitkan Rancangan Peraturan Desa Cileles tentang Klinik Manajemen UMK Desa “Cileles Sejahtera”; 2) sebagai dinamisator, terwujudlah dialog terbuka antara Akademisi IPDN dengan masyarakat terkait permasalahan UMK; 3) sebagai fasilitator, outputnya adalah tersusunnya inventarisir jenis pelatihan dan manfaatnya yang dapat diselenggarakan oleh Pemerintah Desa Cileles dengan berkolaborasi dengan Akademisi dan pelaku bisnis; 4) sebagai katalisator dalam membangun UMK di Desa Cileles adalah tersampaikannya informasi usaha oleh Akademisi IPDN kepada pelaku UMK dalam penyampaian materi yang telah dilakukan. Kesimpulan dari kegiatan PKM adalah Pemerintah Desa Cileles dan masyarakat pelaku UMK menyambut baik dan memberikan respons positif terkait didirikannya klinik manajemen UMK di Desa Cileles, sebagai wadah bagi pelaku UMK untuk berkonsultasi dan berinovasi, serta sebagai wadah bagi Pemerintah Desa dalam memperkuat perannya dalam mendampingi pelaksanaan usaha pelaku UMK di Desa Cileles dalam jangka panjang.
Diagnostic, Prognostic, and Therapeutic Roles of Gut Microbiota in COVID-19: A Comprehensive Systematic Review
Authors: Farsi Yeganeh , Tahvildari Azin , Arbabi Mahta , Vazife Fateme , Sechi Leonardo A. , Shahidi Bonjar Amir Hashem , Jamshidi Parnian , Nasiri Mohammad Javad , Mirsaeidi Mehdi 
Published: March 2022

IntroductionThe Coronavirus Disease 2019 (COVID-19) pandemic caused by Severe Acute Respiratory Coronavirus 2 (SARS-CoV-2) emerged in late December 2019. Considering the important role of gut microbiota in maturation, regulation, and induction of the immune system and subsequent inflammatory processes, it seems that evaluating the composition of gut microbiota in COVID-19 patients compared with healthy individuals may have potential value as a diagnostic and/or prognostic biomarker for the disease. Also, therapeutic interventions affecting gut microbial flora may open new horizons in the treatment of COVID-19 patients and accelerating their recovery.MethodsA systematic search was conducted for relevant studies published from December 2019 to December 2021 using Pubmed/Medline, Embase, and Scopus. Articles containing the following keywords in titles or abstracts were selected: “SARS-CoV-2” or “COVID-19” or “Coronavirus Disease 19” and “gastrointestinal microbes” or “dysbiosis” or “gut microbiota” or “gut bacteria” or “gut microbes” or “gastrointestinal microbiota”.ResultsOut of 1,668 studies, 22 articles fulfilled the inclusion criteria and a total of 1,255 confirmed COVID-19 patients were examined. All included studies showed a significant association between COVID-19 and gut microbiota dysbiosis. The most alteration in bacterial composition of COVID-19 patients was depletion in genera Ruminococcus, Alistipes, Eubacterium, Bifidobacterium, Faecalibacterium, Roseburia, Fusicathenibacter, and Blautia and enrichment of Eggerthella, Bacteroides, Actinomyces, Clostridium, Streptococcus, Rothia, and Collinsella. Also, some gut microbiome alterations were associated with COVID-19 severity and poor prognosis including the increment of Bacteroides, Parabacteroides, Clostridium, Bifidobacterium, Ruminococcus, Campylobacter, Rothia, Corynebacterium, Megasphaera, Enterococcus, and Aspergillus spp. and the decrement of Roseburia, Eubacterium, Lachnospira, Faecalibacterium, and the Firmicutes/Bacteroidetes ratio.ConclusionOur study showed a significant change of gut microbiome composition in COVID-19 patients compared with healthy individuals. This great extent of impact has proposed the gut microbiota as a potential diagnostic, prognostic, and therapeutic strategy for COVID-19. There is much evidence about this issue, and it is expected to be increased in near future.
Incremental Prognostic Value of Pericoronary Adipose Tissue Thickness Measured Using Cardiac Magnetic Resonance Imaging After Revascularization in Patients With ST-Elevation Myocardial Infarction
Authors: Ma Yue , Ma Quanmei , Wang Xiaonan , Yu Tongtong , Dang Yuxue , Shang Jin , Li Guangxiao , Hou Yang 
Published: March 2022

Background and AimPericoronary adipose tissue (PCAT) reflects pericoronary inflammation and is associated with coronary artery disease. We aimed to identify the association between local PCTA thickness using cardiac magnetic resonance (CMR) and prognosis of patients with ST-elevation myocardial infarction (STEMI), and to investigate the incremental prognostic value of PCAT thickness in STEMI after reperfusion.MethodsA total of 245 patients with STEMI (mean age, 55.61 ± 10.52 years) who underwent CMR imaging within 1 week of percutaneous coronary intervention therapy and 35 matched controls (mean age, 53.89 ± 9.45 years) were enrolled. PCAT thickness indexed to body surface area at five locations, ventricular volume and function, infarct-related parameters, and global strain indices were evaluated using CMR. Associations between PCAT thickness index and 1-year major adverse cardiovascular events (MACE) after STEMI were calculated. The prognostic value of the standard model based on features of clinical and CMR and updated model including PACT thickness index were further assessed.ResultsPatients with MACE had a more significant increase in PCAT thickness index at superior interventricular groove (SIVGi) than patients without MACE. The SIVGi was significantly associated with left ventricular ejection fraction (LVEF), infarct size, and global deformation. SIVGi &gt; 4.98 mm/m2 was an independent predictor of MACE (hazard ratio, 3.2; 95% CI: 1.6–6.38; p &lt; 0.001). The updated model significantly improved the power of prediction and had better discrimination ability than that of the standard model for predicting 1-year MACE (areas under the ROC curve [AUC] = 0.8 [95% CI: 0.74–0.87] vs. AUC = 0.76 [95% CI: 0.68–0.83], p &lt; 0.05; category-free net reclassification index [cfNRI] = 0.38 [95% CI: 0.1–0.53, p = 0.01]; integrated discrimination improvement [IDI] = 0.09 [95% CI: 0.01–0.18, p = 0.02]).ConclusionsThis study demonstrated SIVGi as an independent predictor conferred incremental value over standard model based on clinical and CMR factors in 1-year MACE predictions for STEMI.
Variation of Thermal Infrared Brightness Temperature Anomalies in the Madoi Earthquake and Associated Earthquakes in the Qinghai-Tibetan Plateau (China)
Authors: Yang Xing , Zhang Tie-bao , Lu Qian , Long Feng , Liang Ming-jian , Wu Wei-wei , Gong Yue , Wei Jia-xi , Wu Jia 
Published: March 2022

We processed MODIS data received from ground receiving stations into the spatial range of the Qinghai-Tibetan Plateau (China) and the eastern margin of the plateau, and then 283 K was set as the threshold value to remove the area covered by clouds. The monthly background field was calculated based on 17 years’ data, then we obtained the spatial Brightness Temperature anomaly of the current month by deducting the background field. Furthermore, the Brightness Temperature anomaly curves for secondary tectonic blocks in the plateau were calculated. The data indicated that since June 2020, the Brightness Temperature radiation within the Qinghai-Tibetan Plateau began to increase abnormally, starting from the western part of the study area and expanding eastward to cover the entire plateau. In January 2021, such an anomaly was seen again, extending to the Sichuan-Yunnan Block in the easternmost part of the study area in april. With the ongoing anomaly, a series of moderate and strong earthquakes occurred in the Qinghai-Tibetan Plateau, and finally, on 22 May 2021, the M7.4 earthquake struck the Madoi County. Moreover, according to the internal Brightness Temperature time series curves of the different secondary tectonic blocks, the Brightness Temperature has increased simultaneously since the beginning of 2020. A twofold standard deviation was found in the middle-east segment of the Bayanhar Block and the Qiangtang Block in October 2020, and an almost twofold standard deviation was found in March, while a twofold standard deviation was found in the Sichuan-Yunnan Block in april 2021. The occurrence of earthquakes in the plateau before the Madoi earthquake coincided with an upward trend of the time series curve. The spatial anomaly of Brightness Temperature over the Qinghai-Tibetan Plateau disappeared and the Brightness Temperature time series curve dropped drastically after the Madoi earthquake. The development of spatial anomaly of Brightness Temperature and the time series curve both coincide with the occurrence of earthquakes and are consistent with the generation of tectonic stress in the Qinghai-Tibetan Plateau. Our study showed that thermal infrared Brightness Temperature radiation reasonably reflects regional stress development and enables the detection of anomalies prior to moderate and strong earthquakes.
Climatic and Ecological Changes in the Subtropical High Andes During the Last 4,500 Years
Authors: Mayta Cesar , Maldonado Antonio 
Published: March 2022

The effects of climate change may be more evident in mountainous areas. In these areas, an increase in temperature and a decrease in precipitation can reduce the amount of snow, which represents a source of water for human consumption and vegetation. To analyze the effects of climate change on vegetation, it is possible to examine the climate–vegetation relationship in the past and observe the influence of variation in temperature and precipitation on the dynamics of plant communities. The aim of the present work was to describe the climate–vegetation dynamics of the last 4,500 years in the high subtropical Andes of Chile (30°S). The paleoclimatic reconstruction was carried out through the analysis of fossil pollen and macroscopic carbon obtained from sediment cores from two high Andean lakes. The dynamics of the vegetation was analyzed taking into account the alpha and beta diversity. The pollen and carbon records showed three contrasting periods during the last 4,500 years. From the beginning of the sequences until ∼1900 cal. yr BP, relatively dry climatic conditions are suggested, with a slight trend toward more humid conditions after 2,700 cal. yr BP. Pollen records from ∼1900 to ∼600 cal. yr BP suggest wetter conditions than today. Finally, relatively arid conditions have reappeared in the last ∼600 years. The diversity analysis showed that the climate mainly influences the composition of taxa in the communities (beta diversity) and not the richness (alpha diversity). In periods of dry/wet transition and vice versa, beta diversity changes. On the other hand, richness remains relatively constant throughout the record.