bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Long-Term Survival Between cT1N0 Stage Esophageal Cancer Patients Receiving Endoscopic Dissection and Esophagectomy: A Meta-Analysis
Authors: Lu Wei , Li Peng , Wen Wu , Jian Yi 
Published: May 2022

BackgroundEndoscopic dissection (ED) shows relatively high clinical value in early esophageal cancer (cT1N0) such as lower incidence of postoperative complications and hospitalization costs and enhanced recovery. However, whether ED still has certain advantages over esophagectomy in terms of long-term survival remains unclear.PurposeThe aim of this meta-analysis was to compare the long-term outcomes of ED and surgery in the treatment of cT1N0 esophageal cancer.MethodsSeveral electronic databases including the PubMed, EMBASE, Web of Science and Cochrane Library databases were searched up to April 7, 2022 for studies which compared the overall survival (OS) and disease-specific survival (DSS) of cT1N0 esophageal cancer patients receiving the ED or esophagectomy. The hazard ratios (HRs) and 95% confidence intervals (CIs) were combined and all statistical analysis was conducted through STATA 15.0 software.ResultsA total of 12 studies involving 3,732 patients were enrolled. No significant difference in the OS between ED and surgery groups was observed (HR = 0.78, 95% CI, 0.59–1.04, p = 0.089). However, the DSS of the ED group was significantly longer than that of the surgery group (HR = 0.56, 95% CI, 0.39–0.82, p = 0.003).ConclusionIn overall, the current evidence manifested that the long-term survival of cT1N0 esophageal cancer patients undergoing ED was not worse than that of patients undergoing esophagectomy. ED may be considered as the primary treatment for cT1N0 esophageal carcinoma patients.
Gene-Based Methods for Estimating the Degree of the Skewness of X Chromosome Inactivation
Authors: Li Meng-Kai , Yuan Yu-Xin , Zhu Bin , Wang Kai-Wen , Fung Wing Kam , Zhou Ji-Yuan 
Published: May 2022

Skewed X chromosome inactivation (XCI-S) has been reported to be associated with some X-linked diseases, and currently several methods have been proposed to estimate the degree of the XCI-S (denoted as γ) for a single locus. However, no method has been available to estimate γ for genes. Therefore, in this paper, we first propose the point estimate and the penalized point estimate of γ for genes, and then derive its confidence intervals based on the Fieller’s and penalized Fieller’s methods, respectively. Further, we consider the constraint condition of γ∈[0, 2] and propose the Bayesian methods to obtain the point estimates and the credible intervals of γ, where a truncated normal prior and a uniform prior are respectively used (denoted as GBN and GBU). The simulation results show that the Bayesian methods can avoid the extreme point estimates (0 or 2), the empty sets, the noninformative intervals ([0, 2]) and the discontinuous intervals to occur. GBN performs best in both the point estimation and the interval estimation. Finally, we apply the proposed methods to the Minnesota Center for Twin and Family Research data for their practical use. In summary, in practical applications, we recommend using GBN to estimate γ of genes.
Development of a Patient Preference Survey for Wearable Kidney Replacement Therapy Devices
Authors: Flythe Jennifer E. , Forfang Derek , Gedney Nieltje , White David M. , Wilkie Caroline , Cavanaugh Kerri L. , Harris Raymond C. , Unruh Mark , Squillaci Grace , West Melissa , Mansfield Carol , Soloe Cindy S. , Treiman Katherine , Wood Dallas , Hurst Frank P. , Neuland Carolyn Y. , Saha Anindita , Sheldon Murray , Tarver Michelle E. 
Published: May 2022

Key Points

We included the risks of serious bleeding and serious infection based on patient concerns and regulator input about future trial end points.The survey will estimate maximal acceptable risks for serious bleeding and infection and willingness to wait for devices with lower risk.

Background
Recent innovations have the potential to disrupt the current paradigm for kidney failure treatment. The US Food and Drug Administration is committed to incorporating valid scientific evidence about how patients weigh the benefits and risks of new devices into their decision making, but to date, premarket submission of patient preference information (PPI) has been limited for kidney devices. With input from stakeholders, we developed a survey intended to yield valid PPI, capturing how patients trade off the potential benefits and risks of wearable dialysis devices and in-center hemodialysis.

Methods
We conducted concept elicitation interviews with individuals receiving dialysis to inform instrument content. After instrument drafting, we conducted two rounds of pretest interviews to evaluate survey face validity, comprehensibility, and perceived relevance. We pilot tested the survey with in-center hemodialysis patients to assess comprehensibility and usability further. Throughout, we used participant input to guide survey refinements.

Results
Thirty-six individuals receiving in-center or home dialysis participated in concept elicitation (N=20) and pretest (N=16) interviews. Participants identified reduced fatigue, lower treatment burden, and enhanced freedom as important benefits of a wearable device, and many expressed concerns about risks related to device disconnection—specifically bleeding and infection. We drafted a survey that included descriptions of the risks of serious bleeding and serious infection and an assessment of respondent willingness to wait for a safer device. Input from pretest interviewees led to various instrument modifications, including treatment descriptions, item wording, and risk-level explanations. Pilot testing of the updated survey among 24 in-center hemodialysis patients demonstrated acceptable survey comprehensibility and usability, although 50% of patients required some assistance.

Conclusions
The final survey is a 54-item web-based instrument that will yield estimates of the maximal acceptable risk for the described wearable device and willingness to wait for wearable devices with lower risk.
Digitalization: educational context
Authors: Matvienko Oksana , Tsyvin Michael 
Published: May 2022

The article is devoted to identifying approaches to the phenomenon of digitalization in the educational context.
The differences in the understanding of the concepts of "informatization" and "digitalization" are considered and the problems arising in the digital transformations of education are emphasized.
The approaches of domestic scientists to digitalization of education are given and it is revealed, the main problem is seen in acquisition of digital skills by all participants of educational process, the main problem directions of researches are chosen. Autors of publications form models of competencies and function of a teacher in a digital educational environment.
The article emphasizes the unrepresentation of works in which the authors would identify possible negative socio-cultural and moral problems of digitalization and suggest ways to prevent and overcome them.
Adequate to modern problems of digitalization of education is the direction of research proposed by Ukrainian teachers called "digital humanistic pedagogy".
Attention is paid to the new term "digital didactics" in the terminology of pedagogical research, the approaches to its understanding are singled out.
Risks of humanitarian character which arise in the conditions of digitalization of education are revealed, attention is paid to cases of sharply negative attitude of teachers to distance learning.
Emphasis is placed on the existence of "stress of social change", which is caused by the latest technological advances and the introduction of innovations that change the format of education, its didactic and technological components.
It is concluded that the processes of digitalization of education require close attention to its socio-psychological component, information and psychological security of all participants in the educational process and further development of theory and practice of "digital humanistic pedagogy" — in its broadest sense.
Degrees in Link Graphs of Regular Graphs
Authors: Benjamini Itai , Haslegrave John 
Published: May 2022

We analyse an extremal question on the degrees of the link graphs of a finite regular graph, that is, the subgraphs induced by non-trivial spheres. We show that if $G$ is $d$-regular and connected but not complete then some link graph of $G$ has minimum degree at most $\lfloor{2d/3}\rfloor-1$, and if $G$ is sufficiently large in terms of $d$ then some link graph has minimum degree at most $\lfloor{d/2}\rfloor-1$; both bounds are best possible. We also give the corresponding best-possible result for the corresponding problem where subgraphs induced by balls, rather than spheres, are considered.
We motivate these questions by posing a conjecture concerning expansion of link graphs in large bounded-degree graphs, together with a heuristic justification thereof.
On the Subspace Choosability in Graphs
Authors: Chawin Dror , Haviv Ishay 
Published: May 2022

A graph $G$ is said to be $k$-subspace choosable over a field $F$ if for every assignment of $k$-dimensional subspaces of some finite-dimensional vector space over $F$ to the vertices of $G$, it is possible to choose for each vertex a nonzero vector from its subspace so that adjacent vertices receive orthogonal vectors over $F$. The subspace choice number of $G$ over $F$ is the smallest integer $k$ for which $G$ is $k$-subspace choosable over $F$. This graph parameter, introduced by Haynes, Park, Schaeffer, Webster, and Mitchell (Electron. J. Comb., 2010), is inspired by well-studied variants of the chromatic number of graphs, such as the (color) choice number and the orthogonality dimension.
We study the subspace choice number of graphs over various fields. We first prove that the subspace choice number of every graph with average degree $d$ is at least $\Omega(\sqrt{d/\ln d})$ over any field. We then focus on bipartite graphs and consider the problem of estimating, for a given integer $k$, the smallest integer $m$ for which the subspace choice number of the complete bipartite graph $K_{k,m}$ over a field $F$ exceeds $k$. We prove upper and lower bounds on this quantity as well as for several extensions of this problem. Our results imply a substantial difference between the behavior of the choice number and that of the subspace choice number. We also consider the computational aspect of the subspace choice number, and show that for every $k \geq 3$ it is $NP$-hard to decide whether the subspace choice number of a given bipartite graph over $F$ is at most $k$, provided that $F$ is either the real field or any finite field.
ANALYSIS OF POSSIBILITY FOR USING A MODERN UNIVERSAL MODULAR MEASURING SYSTEM OF QUANTUMX SERIES FOR TESTS OF ARMAMENT AND MILITARY EQUIPMENT OF VARIOUS FUNCTIONAL PURPOSES
Authors: Tertyshnik Y. , Shein I. , Potapov O. , Sokorynska N. , Ratushny S. 
Published: May 2022

The article examines the possibility for using a modern universal modular measuring system of QUANTUMX series for testing equipment for various functional purposes.
The research was conducted by the method of system analysis of technical characteristics of the system.
The purpose of the research was to study the technical characteristics, principles of construction of a modern universal modular measuring system of QUANTUMX series of foreign production, its ability to register the necessary parameters of equipment systems for various functional purposes, the possibility of its application in testing.
Analysis of technical characteristics and particularities of the use of modern universal modular measuring system during testing of equipment showed that:
modern measuring system can be used to measure the parameters of equipment of domestic and foreign production, which will make easier and automate the process of measurement as well as minimize the number of errors that occur during their implementation;
measuring system, based on the principle of QUANTUMX is universal. It will ensure a proper measurement process in the course of testing equipment and its components. It will also make possible to measure parameters in systems of different functional purposes (static and dynamic characteristics of objects, temperature, pressure, vibration, overload and other indicators);
usage the capabilities of the measuring system will reduce the time to decide on the feasibility of supplying new (upgraded) models of equipment of the Armed Forces and extend the service life of existing samples.
The results of the work should be used in the study of the possibility of laboratory measuring instrumentation acquisition for equipment testing by research institutions and industrial enterprises.
Peningkatan Literasi Digital Dalam Pembuatan Bahan Ajar Multimedia
Authors: Rahmawati Yelni , Suharyati Henny 
Published: May 2022

<p>Tujuan dari penulisan ini untuk mendeskripsikan implementasi peningkatan literasi digital pembuatan bahan ajar multimedia. Kegiatan ini dilaksanakan mengacu pada kebutuhan guru dalam membuat bahan ajar multimedia sesuai dengan kondisi saat ini yang sedang pandemi Covid 19. Pembelajaran daring dilakukan di tingkat sekolah PAUD sampai jenjang pendiikan tinggi. Sekolah PAUD banyak dibentuk dan didirikan oleh masyarakat dengan sumber daya manuasia (guru), sarana prasarana dan dana yang sangat terbatas, namun dalam praktiknya mereka harus mampu membuat bahan ajar yang menarik dan berbasis pada ilmu pengetahuan dan teknologi. Populasi dari diseminasi ini adalah Satuan Padud Ssejenis (SPS) PAUD Gandaria yang berlokasi di Tegalgundil, Bogor Utara. Sasarannya adalah guru SPS PAUD Gandaria berjumlah 10 orang.Hasil identifikasi terdapat 2 orang guru yang mampu menggunakan aplikasi Microsoft Office, sementara 8 orang lainnya perlu pelatihan yang intensif. Metode pelaksanaannya pertama melakukan survei tempat, sampel, memberikan pre test sebelum pelatihan, dilanjutkan dengan post test setelah pelatihan. Target kegiatan ini adalah meningkatnya kemampuan literasi digital pada guru PAUD dalam membuat bahan ajar multimedia. Hasil dari pelatihan literasi digital, guru PAUD Gandaria dapat membuat bahan ajar yang kreatif dan inovatif dalam kegiatan belajar mengajar.</p>
Quantifying Wave–Particle Interactions in Collisionless Plasmas: Theory and Its Application to the Alfvén-mode Wave
Authors: Zhao Jinsong , Lee Louchuang , Xie Huasheng , Yao Yuhang , Wu Dejin , Voitenko Yuriy , Pierrard Viviane, 
Published: May 2022

Abstract
Wave–particle interactions can induce energy transfer at different timescales in collisionless plasmas, which leads to the reshaping of the particle velocity distribution function. Therefore, how to quantify wave–particle interactions is one of the fundamental problems in the heliosphere and in astrophysical plasmas. This study proposes a systematic method to quantify linear wave–particle interactions based on the Vlasov–Maxwellian model. We introduce energy transfer rates with various expressions by using perturbed electric fields and perturbed particle velocity distribution functions. Then, we use different expressions of the energy transfer rate to perform a comprehensive investigation of wave–particle interactions of the Alfvén-mode wave. We clarify the physical mechanisms responsible for the damping of the Alfvén-mode wave in wavevector space. Moreover, this study exhibits for the first time evident signatures of wave–particle interactions between Alfvén-mode waves and resonant/nonresonant particles in the velocity space. These resonant and nonresonant particles can induce energy transfer in opposite directions, which leads to self-regulation of the particle velocity distribution function. Furthermore, this study exhibits a comprehensive dependence of wave–particle interactions of the Alfvén-mode wave on the wavenumber and plasma beta (the ratio between the plasma thermal pressure and the magnetic pressure). These results illustrate that the proposed method would be very useful for quantifying different types of linear wave–particle interactions of an arbitrary wave mode.
Contagieuse colère : un outil clinique à l’ère d’une crise sanitaire
Authors: Salembier Benoiste 
Published: May 2022

Dans cet article nous proposons de relier la question de la colère au transfert. Cette colère qui lors de la crise sanitaire a été particulièrement contagieuse, aussi bien dans notre quotidien qu’exprimée dans l’espace thérapeutique. Si cette crise sanitaire n’est pas responsable de l’agressivité des patients et de l’équipe que nous accompagnons et que nous présentons dans cet article, elle a participé activement aux conditions accentuant cette colère (séparation, isolement, menace de mort, angoisse). Aussi, si nous voulons soigner ces maux colériques, faut-il encore être capable de les accueillir afin de leur proposer des réponses qui usent d’autres mots. Afin de déplier cette réflexion nous nous référons à de nombreuses références psychanalytiques notamment en ce qui concernant le concept de transfert et de l’agressivité ainsi que quelques références philosophiques pour cerner l’objet qui nous intéresse : la colère.
Faire famille en temps de pandémie : difficultés et opportunités
Authors: Venard Gaelle , Mouton Bénédicte , Zimmermann Grégoire , Van Petegem Stijn 
Published: May 2022

La vie quotidienne des familles a été bouleversée durant la crise sanitaire liée à la pandémie du COVID-19. Cet article propose une revue de la littérature afin d’observer la manière dont les parents se sont adaptés en fonction de leurs réalités et de leurs ressources tant individuelles que conjugales, familiales ou sociales. Dans un contexte idéologique de « sur-responsabilisation parentale », la pandémie est venue exacerber la pression sociale et les injonctions envers les parents. De nombreuses études indiquent que les parents ont ressenti des niveaux élevés de stress, d’anxiété et d’épuisement, en particulier les figures maternelles qui ont souvent porté la double charge de poursuivre leur activité professionnelle et de garantir l’organisation et le bon fonctionnement de la famille dans ce contexte d’adversité. Dans un tel contexte, les parents se sont trouvés à risque de mettre en place des pratiques de surprotection parentale qui peuvent fragiliser l’autonomie et le bien-être des enfants, notamment des adolescents. Des conséquences positives ont été aussi identifiées chez certains parents, comme une meilleure conciliation entre vie familiale et professionnelle et une coparentalité plus équilibrée. Ainsi, certains parents ont été confrontés à des difficultés durant la pandémie qu’ils ont vécue comme une source de pression supplémentaire, alors que d’autres ont traversé cette crise de manière positive. Leur capacité d’adaptation pourrait s’avérer une ressource précieuse pour les potentielles crises à venir.
L’autisme, une fois sorti de son enclos pathologique
Authors: Thomas Marie-Claude 
Published: May 2022

Le champ freudien – qui a reçu sans critiques l’entité pathologique « autisme » – peut, avec les outils construits par J. Lacan, ceux de M. Foucault et les études de M. de Certeau, déplacer l’entité autisme en « phénomène-autisme » et le concevoir comme symptôme civilisationnel.
Dans les brèches de la fiction, un regard
Authors: Corpelet Dominique 
Published: May 2022

L’écrivain argentin Jorge Luis Borges, dans ses fictions, mais aussi dans sa poésie, tourne autour de la question du regard. Alors qu’il déploie dans son œuvre tout un jeu spéculaire d’images qui se redoublent et s’emboîtent les unes dans les autres, et ce à l’infini, au point parfois de susciter une fascination qui porte parfois au vertige, parfois, un regard, sous les espèces d’une chose monstrueuse, surgit d’une brèche. C’est une levée du voile sur un regard, ici à entendre comme objet a, un regard comme présence réelle, hors du champ du signifiant et hors image. On passe alors de la paisible contemplation, où s’élude le manque, à l’effroi, lorsque l’objet, en excès, se donne à voir. Nous proposons ici de lire Borges avec Lacan (spécialement les leçons qu’il consacre au regard dans les Séminaires X et XI). Par l’écriture d’un univers fantastique, Borges tente de cerner un regard. Entre les mots, un réel.
Lecture psychanalytique de récits d’origine d’ethnies africaines
Authors: Barry Aboubacar , Aka Dago-Akribi Hortense 
Published: May 2022

Des anthropologues ont émis, depuis plusieurs décennies, des controverses sur la réalité de ce qu’on appelle « ethnie » quand on parle de l’Afrique, sur le contenu réel de cette notion ainsi que sur ce qui distingue une ethnie d’une autre avec laquelle elle partage une certaine communauté culturelle. En analysant les récits qu’ils ont recueillis sur l’origine de différentes ethnies, certains d’entre eux se sont rendu compte des difficultés qu’il y avait à conclure à partir de telles légendes qui sont loin d’obéir à la logique de l’histoire. Ce texte propose une lecture de certains de ces récits, mythes et légendes à partir des notions psychanalytiques de « roman familial », de « souvenirs d’enfance » et de « fantasmes originaires ».
La « théorie politique » : entre philosophie de la politique et politique dans la théorie
Authors: Pranchère Jean-Yves 
Published: May 2022

Relire l’article d’Isaiah Berlin publié en 1961 dans le numéro de la Revue française de science politique consacré à la théorie politique oblige à en reprendre les questions à la lumière des développements de la discipline dans l’aire francophone. La différence de la théorie politique avec la science politique d’une part et la philosophie politique d’autre part demande à être saisie selon plusieurs enjeux : l’articulation du constat empirique, de l’analyse logique et de l’histoire conceptuelle ; la tension entre le raisonnable et le rationnel ; la distinction entre la politique et le politique ; la pratique de la réflexivité sociale à l’intersection des processus historiques, des valeurs immanentes aux modes de vie et des choix normatifs.
Addendum : propositions pour des analyses processuelles et relationnelles des contributions de l’État aux (dés)investissements politiques
Authors: Barrault-Stella Lorenzo 
Published: May 2022

Cet article revient sur le post-scriptum séminal d’Olivier Fillieule relatif aux carrières militantes dans la Revue française de science politique en 2001. Il explore ses conditions de possibilité, ses multiples apports, les controverses et son devenir, avant de proposer un programme complémentaire outillé par la sociologie de l’État et de l’action publique. À rebours des cloisonnements disciplinaires, l’enjeu est de questionner les processus d’étatisation des (dés)investissements politiques. Deux pistes sont esquissées : d’une part intégrer l’économie des rapports à l’État (l’étatisation plurielle des individus) dans l’analyse processuelle des investissements politiques, d’autre part, et en lien, prendre au sérieux l’hypothèse relationnelle du façonnage étatique des situations de (dé)mobilisation (l’étatisation des situations) par les institutions et l’action publique.
Agroécologie
Authors: Altieri Miguel A. , Nicholls C.I. , Thommes Nicolas 
Published: May 2022

Face aux aberrations de l’agriculture industrielle, l’agroécologie présente des avantages sociaux et environnementaux supérieurs aux autres alternatives, eu égard aux défis du 21 e siècle. Si des millions de paysans la mettent déjà en pratique en Asie, en Afrique et en Amérique latine, notamment grâce aux méthodes de diffusion participative, les obstacles à une accélération de son expansion doivent encore être levés.
Agroécologie
Authors: Shambu Prasad Chebrolu , Lejeune Guillaume 
Published: May 2022

La politique indienne des sciences, de la technologie et de l’innovation adoptée en 2013 a déçu les espoirs de voir la production scientifique se démocratiser dans le pays. Le manque d’intérêt pour le Système d’intensification du riz (SIR) illustre bien la frilosité du pouvoir scientifique institué vis-à-vis des déclinaisons « citoyennes » des sciences.