bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of Iced Normal Saline Combined with Cocktail Perfusion in Total Knee Arthroplasty: randomized controlled trial
Authors: Sui Laijian , Wang Xiufeng , Gai Pengzhou , Wang Jinwei , Qi Xiaojun , Wang Jing , Jiang Aihua , Wang Guangda 
Published: October 2022

Abstract
Objective:
The present study was designed to investigate the safety and effectiveness of iced normal saline combined with cocktail perfusion during total knee arthroplasty (TKA). This was a random, double-blind, parallel-group study conducted in China.
Methods:
Seventy patients undergoing unilateral total knee replacements were assessed in the present study. Among them, sixty patients with confirmed primary knee osteoarthritis in stage IV were recruited and divided into three groups randomly, three different intro-operative articular cavity perfusion treatments were given according to the randomized and controlled rule. One way ANOVA analysis on visual analogue scale (VAS) score, functional recovery, drainage, and edema of the affected limb were performed to assess the efficiency of the treatment in the following three days after the operation. The participants, care givers, and those assessing the outcomes were blinded to group assignment.
Results:
Postoperative drainage in group A (n = 20) and B (n = 20) reduced significantly (P < 0.05). The IHC scores of the surgical limbs were markedly lower comparing with the control group (n = 20) (P < 0.05). No differential postoperative edema was observed and the patient acquired better rehabilitation in group A and B than control group. Compared with group A, no differential postoperative drainage, edema or other side effects were seen in group B (P > 0.05). The VAS score of group B was significantly lower than in group A(P < 0.05). Postoperative recovery of the surgical limb function in group B was better than in group A (P < 0.05).
Conclusions:
Intra-operation articular cavity perfusion therapy with iced normal saline combined with cocktail perfusion therapy can greatly reduce the early inflammation, contributing to the better rehabilitation of TKA.
Classification of generalized singular points for piecewise smooth systems with application for the ‎Wien bridge oscillator
Authors: Zarei Zohreh , Amaleh Majid Karimi 
Published: October 2022

Abstract
In this paper, we have tried to classify different states of ‎flow‎ behavior for piecewise smooth systems near generalized equilibrium points. Based on the definition of generalized equilibrium points, seven categories are introduced for these points and then in each category, states that can occur are introduced. Then, a kind of bifurcation due to changing the perturbation parameter has been investigated for them‏. ‎Finally, ‎Wien bridge oscillator will be used as an application to the content of this article.‎
Rhizosphere microorganisms and soil physicochemical properties of restored wetland plant communities at cutting slash of Populus deltoides in Dongting Lake
Authors: Tan Sijia , Jiang Lijuan , Liu Jingyi , Zeng Zhangquan , Xiao Yaqin , Wu Xiaoli , Niu Yandong 
Published: October 2022

Abstract
Carex spp. and Artemisia selengensis communities are typical renewal wetland plant communities at cutting slash of Populus deltoides. However, how rhizosphere microorganisms and soil factors interact during natural restoration in plant communities is unknown. Plots containing Carex spp. and Artemisia selengensis in the slash area were investigated, and the P. deltoides plantation area at a lake shore was sampled as a control. The results revealed that the richness and diversity indices of the fungal community in the Carex spp. community were higher than those in the A. selengensis and P. deltoides undergrowth communities. Ascomycota was the dominant phylum in the soil of Carex spp. community whereas Basidiomycota was the dominant phylum in the A. selengensis community. The richness and diversity indices of the rhizosphere bacterial community in the control were higher than those in communities of Carex spp. and A. Selengensis. Proteobacteria and Actinobacteria were the dominant phyla of the rhizosphere bacterial community in the control plot. Soil water content (WC), proportion of clay (CY), and nutrient content, as well as catalase activity (CAT) in the soil of Carex spp. community were the highest, whereas those in the control were the lowest. Conversely, the bulk density (BK) and proportion of gravel in the control plot were the highest. RDA found that the CY, organic matter (OM), ammonium nitrogen (AN) and nitrate nitrogen (NN) content in the soil were the key factors affecting the structure and composition of the rhizosphere microbial community.
Atmospheric Mass Density Model PVA: An atmospheric density model derived from the Position, Velocity and Acceleration of a spacecraft
Authors: de Freitas Wantuir Aparecido , Fenili André 
Published: October 2022

Abstract
Neutral densities and winds are critical parameters for understanding the physics and dynamics of the mesosphere, the thermosphere and the ionosphere systems. The continuous measurements available for these parameters are largely obtained from the ground (geographically fixed locations) and usually with limited altitude coverage. As the altitude rises in relation to sea level, the atmospheric density decreases exponentially. The rate of variation of this parameter depends on the latitude, longitude and season of the year, as well as on the solar and magnetic activity. Obtaining information on atmospheric density at determined altitude levels enhances the understanding of mesosphere, thermosphere and ionosphere coupling systems. In order to estimate the atmosphere density in regions of interest, the analysis of the drag effect of the atmosphere on a spacecraft is investigated. With the aim of understanding the dissipative effect of the drag forces, a scenery is created. When the spacecraft is in operation the position, velocity and acceleration are well determined. So, it can be traced and its location determined in any interval of time. Based on information about the spacecraft states, one can infer about the behavior of the atmospheric density. The proposal of this paper is to develop a methodology using a priori knowledge of the spacecraft states in order to provide a wider horizontal sample of the atmospheric densities.
Response of thermal conductivity of loess after high temperature in northern Shaanxi burning rock area, China
Authors: Wang Shaofei , Sun Qiang , Li Delu , Wang Nianqin 
Published: October 2022

Abstract
The thermal conductivity of loess plays an important role in ecological restoration design and the calculation of roadbed and slope stability. This study uses 60 loess samples from Shaanxi Province of China as raw material. The loess samples were heated to high temperature in an unclosed muffle furnace and then cooled to room temperature. Subsequently, the heat conduction coefficient (λ), specific heat capacity (c) and thermal diffusion coefficient (α) of the sample were measured. Between 23–900 °C, with temperature increasing, λ decreased from 0.90 to 0.46 W/m·K, c decreased from 1.60 to 1.23 J/kg·K, α decreased from 0.59 to 0.38 m2/s. The test results show that, after being exposed to high temperature, the thermal conductivity of loess tends to weaken. This has a very important relationship with the pore characteristics of loess.
Polyacrylamide Hydrogels With Amber for Plants Micropropagation
Authors: Kernosenko Lyudmyla , Samchenko Kateryna , Goncharuk Olena , Pasmurtseva Natalya , Poltoratska Tetiana , Siryk Olena , Dziuba Oksana , Mironov Oleg , Szewczuk-Karpisz Katarzyna 
Published: October 2022

Abstract
The in vitro cultivation and reproduction of plants is one of the most modern and promising methods of cultivating valuable plants using artificial nutrient media. In this work, a new solid nutrient media for plant micropropagation based on highly dispersed polyacrylamide hydrogel (PAAG) with amber powder was synthesized and investigated. PAAG was synthesized by homophase radical polymerization with grounded amber addition. FTIR (Fourier transform infrared spectroscopy) and rheological studies were used to characterize structural properties of the materials. The synthesized hydrogel showed physicochemical and rheological parameters similar to the standard agar media. The estimation of acute toxicity of PAAG-amber was performed based on the influence of washing waters on the viability of the selected plant seeds (pea and chickpea) and animal (Daphnia magna). It proved its biosafety after four washes. The impact on plant rooting was studied using multiplication of Cannabis sativa on synthesized PAAG-amber saturated with Murashige-Skoog (MS) medium and compared with agar gel with MS. Developed substrate stimulated the rooting of the plants up to more than 98% in comparison to standard agar medium (95%). Also, PAAG-amber nutrient medium markedly enhanced metric indicators of seedling: root length increased by 28%, stem length – by 26.7%, root weight – by 167%, stem weight – by 67%, root and stem length – by 27%, root and stem weight – by 50%. This means that the developed hydrogel significantly accelerates reproduction and allows obtaining a larger amount of plant material within a shorter period than the standard agar medium.
Multi-Variate and Multi-dimensional CFAR Detection of Breast Cancer
Authors: Albaaj Azhar , Norouzi Yaser , Moradi Gholamreza 
Published: October 2022

Abstract
Breast cancer is the most common type of cancer in females. In many cases, the mortality rate can be drastically lowered if the disease is detected early. Due to its safety and lack of risk to the patient, microwave breast imaging is considered a potential replacement for mammography. This paper presents a breast cancer detection approach based on the Multi-Variate and Multi-Dimensional Constant False Alarm Rate (MVMD-CFAR) method. This method has several advantages over mammography using x-rays, including increased patient comfort and lower costs. On an open-source experimental database derived from the University of Manitoba Microwave Mammography Dataset UM-BMID, the performance of the (2D-CFAR) method is evaluated by examining the available data set for breast microwave sensing. We segregate infected and healthy samples and assessed the probability density function PDF for pictures of normal and malignant tissue. The third dimension of the algorithm is the image's color data, which comprises three variables (three colors). Initial testing show that the MVMD-CFAR detector is highly effective, with a detection probability of 97.4% and a false alarm probability of 10%. However, a few challenges must be overcome before this imaging technique can reach its full potential and be implemented in clinical settings.
Formation and Properties of Magnetic Biochar
Authors: Victor Nwosu Obinnaya Chikezie 
Published: October 2022

Abstract
Magnetic biochar made from agricultural biomass waste such as SRC willow, which is a densely planted, high-yielding energy crop and one of the leading sources of renewable energy production, combined with iron (II) chloride and iron (III) chloride, is a multi-functional material for land remediation and agricultural applications. Two magnetic biochar's (1.0 M iron solution magnetic biochar and 0.1 M iron solution magnetic biochar) were prepared by the chemical mixture and co-precipitation of iron (II) chloride tetrahydrate and iron (III) chloride on SRC willow with a particle size of less than 2 mm (about 0.08 in). The mixture of SRC willow with iron (II) chloride tetrahydrate and iron (III) chloride was then dried in the oven and pyrolyzed at 400 degrees Celsius. Scanning electron microscopy, Fourier transform infrared spectroscopy, and X-ray diffraction research on the 1.0 M iron solution magnetic biochar and the 0.1 M iron solution magnetic biochar reveal a greater concentration of iron compounds in the 1.0 M iron solution magnetic biochar. Ultraviolet infrared spectrometry was performed on iron (II) chloride tetrahydrate, iron (III) chloride, and copper (II) sulphate pentahydrate. Atomic absorption spectroscopy and ultra-violet spectrometry were performed on copper (II) sulphate pentahydrate and deionized water mixed with 1.0 M iron solution magnetic biochar, 0.1 M iron solution magnetic biochar, and activated for atomic absorption spectroscopy, 0.1 M iron solution magnetic biochar has a greater adsorption capacity than 1.0 M iron solution magnetic biochar for copper (II) sulphate pentahydrate solution. For ultra-violet infrared spectroscopy, the adsorption capacity of magnetic biochar in a 1.0 M iron solution is greater than that of magnetic biochar in a 0.1 M iron solution. Based on these results, both the 1.0 M iron solution magnetic biochar and the 0.1 M iron solution magnetic biochar are good options for removing metal pollutants like copper and restoring land.
Investing the effect of 2100 MHz frequency electromagnetic field on the male rat reproductive system
Authors: Ghasemiannejadjahromi Fariba , Raji Ahmadreza , Maleki Mohsen , Mirshokraei Pezhman , Kafaeerazavi morteza 
Published: October 2022

Abstract
Background: This research aimed to appraise the 2100 MHz frequency of the new generation of mobile phones on the male rat reproductive system. The genital organ is one of the important systems for sustaining reproduction and generation. The consequences of mobile phone radiation exposure have been a growing general health worry in recent years.
Study design: 35 Wister albino male rats were randomly divided into five groups for this study. The groups were exposed to a 2100 MHz frequency electromagnetic field for 0, 15, 60,120, 180 min/day, 70 consecutive days. At the end of the experiment, serum testosterone levels were measured, and each group was evaluated for epididymal sperm parameters, including mobility, morphology, and viability. Then, immunohistochemistry staining was performed by Cleaved-Caspase 3 antibody to show apoptosis in the testicular tissue.
Results: Our results revealed that serum testosterone levels were significantly reduced in experimental groups (60 and 120 min). In addition, sperm motility was significantly reduced in experimental groups (60, 120, and 180 min), and a significant decline of sperm viability and apoptosis (P=0.001) was observed in all groups.
Conclusion: This study found a significant increase in the number of dead sperm and apoptosis and a significant reduction in motility, which could impair the spermatogenesis process, reduce sexual characteristics, and eventually lower the rate of fertility.
Scale Inhibitor Qualification: Evaluation for Treatment in Brazilian Pre-salt fields
Authors: Borges Eloisa Borges e , Lessa Juliana Vieira 
Published: October 2022

Abstract
Inorganic scale deposition is one of the main challenges related to the flow assurance in the Oil & Gas Industry. The pre-salt oilfields has been becoming very important, especially for the Brazilian market. The operational conditions in these types of scenarios are extremely favorable for precipitation of salts. The main factors for this include high salinity, high temperature and considerable changes on the pH of the produced fluid. For this work, it was possible to predict the scale indexes of some scenarios from Brazilian pre-salt fields throughout software simulations and then, a development of a suitable scale inhibitor. The chemistry showed great performance in avoiding scale precipitation for a long period of test as well as compatibility with high calcium brines. The analyzes carried out included projections on the Scale Soft Pitzer software to evaluate the thermodynamic conditions of the system, compatibility tests with brine, and tests on the DSL (“Dynamic Scale Loop”) equipment, in order to verify the performance of inhibitors under dynamic conditions. The MIC, “minimum inhibition concentration”, found for the PAPEMP based chemical evaluated, was a low one, resulting in a very economical solution for applications in Pre-Salt fields.
Control of a Hippocampal Recurrent Excitatory Circuit by Cannabinoid Receptor-interacting Protein Gap43
Authors: Maroto Irene , Costas-Insua Carlos , Berthoux Coralie , Moreno Estefania , Ruiz-Calvo Andrea , Montero-Fernández Carlos , Macías-Camero Andrea , Martín Ricardo , García-Font Nuria , Sánchez-Prieto José , Marsicano Giovanni , Bellocchio Luigi , Canela Enric , Casado Vicent , Galve-Roperh Ismael , de Sevilla David Fernandez , Rodríguez-Crespo Ignacio , Castillo Pablo , Guzmán Manuel 
Published: October 2022

Abstract
The type-1 cannabinoid receptor (CB1R) is widely expressed in both excitatory and inhibitory nerve terminals, and its activation, by suppressing neurotransmitter release, modulates neural circuits and brain function. While the interaction of CB1R with various intracellular proteins is thought to alter receptor signaling, the identity and role of these proteins are poorly understood. Using a high-throughput proteomic analysis complemented with an array of in vitro and in vivo approaches in the mouse brain, we report that the C-terminal, intracellular domain of CB1R interacts specifically with growth-associated protein of 43 kDa (GAP43). The CB1R-GAP43 interaction occurs selectively at mossy cell axon boutons, which establish excitatory synapses with dentate granule cells in the hippocampus. This interaction impairs CB1R-mediated suppression of mossy cell to granule cell transmission, thereby inhibiting cannabinoid-mediated anti-convulsant activity in mice. Thus, GAP43 acts as a synapse type-specific regulatory partner of CB1R that hampers CB1R-mediated effects on hippocampal circuit function.
Number of vaginal lactobacilli in postmenopausal women with vaginal atrophy before and after treatment with erbium YAG laser, a randomized sham-controlled trial
Authors: Panyawongudom Nuttanun , Panyakhamlerd Krasean , Suwan Ammarin 
Published: October 2022

Abstract
Primary objective: To evaluate the effect of erbium YAG laser on the number of vaginal lactobacilli in postmenopausal women.
Secondary objectives: To evaluate the effects of erbium YAG laser on vaginal atrophy symptoms and vaginal pH in postmenopausal women.
Materials and Methods: A total of 44 postmenopausal women meeting inclusion criteria were randomized in laser group (n=22) and sham group (n=22). Vaginal lactobacilli grading, vaginal pH, vaginal atrophy score and vaginal atrophy symptoms (dryness, irritation, soreness, dyspareunia) wereassessed before and after treatment with erbium YAG laser for 2 consecutive times, 4 weeks interval; the results were compared with the effects of sham procedure. Any adverse events after the treatment were recorded. Statistical analysis was performed by using SPSS program and p < 0.05 was considered statistically significant.
Results: 44women were included and 5were lost to follow-up. Compared with sham procedure, there was an improvement of vaginal lactobacilli grading in laser group (5/20 in laser group and 1/19 in sham group). However, the improvement did not reach statistically significant (adjusted OR = 5.32, 95%CI = 0.5-56.21). Vaginal atrophy symptoms measured by VAS and vaginal pH were improved in both groups without statistically significant difference between groups. Vaginal “dryness” VAS and vaginal atrophy score after treatment were significantly lowered in laser group compared to sham group.
Conclusions: This study showed an improvement in vaginal lactobacilli grading after vaginal laser treatment. However, the difference of vaginal lactobacilli grading after treatment in both groups did not reach statistically significant.
Sociocultural factors associated with Detection of ASD among Culturally and Linguistically Diverse Communities in Australia
Authors: Hussain Aniqa , John James Rufus , Dissanayake Cheryl , Frost Grace , Girdler Sonia , Karlov Lisa , Masi Anne , Alach Tasha , Eapen Valsamma 
Published: October 2022

Abstract

Background
This study aimed to characterise the most common types of first concerns observed by Australian parents regarding initial autism presentation, the average age of first concern (AOC), and associated sociocultural factors including culturally and linguistically diverse (CALD) background of the family.
Methods
A battery of measures relevant to demographics and information about ASD symptoms was completed for 760 participating children.
Results
The mean AOC was 18.2 months. The most common concerns were speech/language delay, variations in sociality and hyperactivity/behavioural changes. Multivariate regression analysis identified that children form a CALD background showed more autism traits and later AOC compared to non-CALD children.
Conclusion
Findings highlighted sociocultural factors that may delay autism diagnosis, and that can be used to create opportunities for earlier identification of autism in multicultural families.
A robot‑aided visuomotor wrist training induces motor and proprioceptive learning that transfers to the untrained ipsilateral elbow
Authors: Zhu Huiying , Wang Yizhao , Elangovan Naveen , Cappello Leonardo , Sandini Giulio , Masia Lorenzo , Konczak Jürgen 
Published: October 2022

Abstract
Background
Learning of a visuomotor task not only leads to changes in motor performance but also improves proprioceptive function of the trained joint/limb system. Such sensorimotor learning may show intra-joint transfer that is observable at a previously untrained degrees of freedom of the trained joint. In addition, it may transfer to the homologous joint of contralateral side.
Objective
Here, we examined if and to what extent such learning transfers to neighboring joints of the same limb and whether such transfer is observable in the motor as well as in the proprioceptive domain. Documenting such intra-limb transfer of sensorimotor learning holds promise for the neurorehabilitation of an impaired joint by training the neighboring joints.
Methods
Using a robotic exoskeleton, 15 healthy young adults (18–35 years) underwent a visuomotor training that required them to make continuous, increasingly precise, small amplitude wrist movements. Wrist and elbow position sense just-noticeable‐difference (JND) thresholds and spatial movement accuracy error (MAE) at wrist and elbow in an untrained pointing task were assessed before and immediately after, as well as 24 hours after training.
Results
First, all participants showed evidence of proprioceptive and motor learning in both trained and untrained joints. The mean JND threshold decreased significantly by 30% in trained wrist (M: 1.26° to 0.88°) and by 35% in untrained elbow (M: 1.96° to 1.28°). Second, mean MAE in untrained pointing task reduced by 20% in trained wrist and the untrained elbow. Third, after 24 hours the gains in proprioceptive learning persisted at both joint, while motor learning gains had decayed to such extent that they were no longer significant at the group level.
Conclusion
Our findings document that a one-time sensorimotor training induces rapid learning gains in proprioceptive acuity and untrained motor performance at the practiced joint. Importantly, these gains transfer almost fully to the neighboring, proximal joint/limb system.