bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining Use Behavior of a Goal-Supporting mHealth App in Primary Care Among Patients With Multiple Chronic Conditions: Qualitative Descriptive Study
Authors: Tahsin Farah , Austin Tujuanna , McKinstry Brian , Mercer Stewart W , Loganathan Mayura , Thavorn Kednapa , Upshur Ross , Steele Gray Carolyn 
Published: October 2022

Background
Although mobile health (mHealth) apps are increasingly being used to support patients with multiple chronic conditions (multimorbidity), most mHealth apps experience low interaction and eventual abandonment. To tackle this engagement issue, when developing an mHealth program, it is important to understand the social-behavioral factors that affect patients’ use behavior.

Objective
The aim of this study was to explore the social and behavioral factors contributing to patients’ use behavior of an mHealth app called the electronic Patient-Reported Outcome (ePRO). The ePRO app supports goal-oriented care delivery in interdisciplinary primary care models.

Methods
A descriptive qualitative study was used to analyze interview data collected for a larger mixed methods pragmatic trial. The original 15-month trial was conducted in 6 primary care teams across Ontario, Canada, between 2018 and 2019. The eligibility criteria for patients were being aged ≥60 years with ≥10 visits within the previous 12 months of study enrollment. For this analysis, patients were classified as long-term or short-term users based on their length of use of the ePRO app during the trial. The Social Cognitive Theory by Bandura was used to categorize social-behavioral factors that contributed to patients’ decision to continue or discontinue using the app.

Results
The patient-provider relationship emerged as a key factor that shaped patients’ experiences with the app and subsequent decision to continue using the app. Other factors that contributed to patients’ decision to continue using the app were personal and social circumstances, perceived usefulness, patients’ previous experience with goal-related behaviors, and confidence in one’s capability. There was an overlap of experience between long- and short-term app users but, in general, long-term users perceived the app to be more useful and their goals to be more meaningful than short-term app users. This observation was complicated by the fact that patient health-related goals were dynamic and changed over time.

Conclusions
Complex patients’ use behavior of a goal-supporting mHealth app is shaped by an array of sociobehavioral factors that can evolve. To tackle this dynamism, there should be an emphasis on creating adaptable health technologies that are easily customizable by patients and able to respond to their changing contexts and needs.

Trial Registration
ClinicalTrials.gov NCT02917954; https://clinicaltrials.gov/ct2/show/NCT02917954
Biomarkers of Exposure and Potential Harm in Exclusive Users of Nicotine Pouches and Current, Former, and Never Smokers: Protocol for a Cross-sectional Clinical Study
Authors: Azzopardi David , Haswell Linsey Ellen , Frosina Justin , McEwan Michael , Gale Nathan , Thissen Jesse , Meichanetzidis Filimon , Hardie George 
Published: October 2022

Background
Tobacco harm reduction (THR) aims to reduce the health burden of cigarettes by encouraging smokers to switch to using alternative tobacco or nicotine products. Nicotine pouches (NPs) are smokeless, tobacco-free, oral products that may be beneficial as part of a THR strategy.

Objective
This 2-center, cross-sectional confinement study conducted in Denmark and Sweden aimed to determine whether biomarkers of exposure (BoEs) to tobacco toxicants and biomarkers of potential harm (BoPHs) in exclusive users of NPs show favorable differences compared with current smokers.

Methods
Participants were healthy NP users (target n=100) and current, former, or never smokers (target n=40 each), as confirmed by urinary cotinine and exhaled carbon monoxide concentrations. During a 24-hour confinement period, participants were asked to use their usual product (NP or cigarette) as normal, and BoEs and BoPHs were measured in blood and 24-hour urine samples, with compliance determined using anabasine, anatabine, and N-(2-cyanoethyl)valine. BoEs and BoPHs were compared between NP users and current, former, and never smokers. Urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (BoE to nicotine-derived nitrosamine ketone) and urinary 8-epi-prostaglandin F2α type III, exhaled nitric oxide, blood carboxyhemoglobin, white blood cell count, soluble intercellular adhesion molecule-1, and high-density lipoprotein cholesterol (BoPHs) were evaluated as primary outcomes. Other measures included urinary 11-dehydrothromboxane B2, forced expiratory volume, carotid intima-media thickness, self-reported quality of life, and oral health.

Results
The results of this study were received in mid-2022 and will be published in late 2022 to early 2023.

Conclusions
The results of this study will provide information on toxicant exposure and biomarkers associated with the development of smoking-related diseases among users of NPs compared with smokers, as well as on the potential role of NPs in THR.

Trial Registration
International Standard Randomised Controlled Trial Number (ISRCTN) ISRCTN16988167; https://www.isrctn.com/ISRCTN16988167

International Registered Report Identifier (IRRID)
DERR1-10.2196/39785
Comparison of noninvasive prenatal screening for defined pathogenic microdeletion/microduplication syndromes and nonsyndromic copy number variations: a large multicenter study
Authors: Yang Li , Bu Guosen , Ma Yuyu , Zhao Jing , Rezak Jiamilla , La Xiaolin 
Published: October 2022

Background:This retrospective study assessed the precision of noninvasive prenatal testing (NIPT) in detecting microdeletion/microduplication syndromes (MMSs) and nonsyndromic copy number variations (CNVs).Methods:The study included 19,086 singleton pregnancies screened on NIPT using high-throughput sequencing. Pregnancies with CNVs on NIPT underwent amniocentesis for karyotyping and CNV sequencing (CNV-seq). We analyzed pathogenic MMSs and nonsyndromic CNVs separately, dividing the CNVs into subgroups based on fragment size and fetal ultrasound findings.Results:A total of 170 abnormalities were detected by NIPT, of which 113 (66.5%) underwent invasive testing. The positive predictive value (PPV) of CNV-seq for all types of CNV detected by NIPT was 35.4%, with PPVs of 61.5 and 27.6% for pathogenic MMSs and nonsyndromic CNVs, respectively. PPVs for NIPT showed different values depending on gestational characteristics, with the highest PPV for NIPT in the group with increased nuchal thickness (66.7%) and for the abnormal ultrasound group (57.1%). CNVs ≤5 Mb with normal ultrasound findings were generally associated with a healthy fetus.Conclusion:NIPT can detect chromosomal aberrations in the first trimester, with high performance for MMSs. However, due to the low PPV for nonsyndromic CNVs, and the good pregnancy outcome in most cases, the introduction of expanded NIPT would cause an increase in unnecessary invasive procedures and inappropriate terminations of pregnancy.
Decontextualized Language Skills in Children with Developmental Language Disorder and Developmental Dyslexia: Evidence from a Word Definition Task
Authors: Dosi Ifigeneia 
Published: October 2022

The present study investigates the development of decontextualized language skills, by means of a word definition task, in children with Developmental Language Disorder (DLD) & Developmental Dyslexia (DD). Although these disorders have a common basis and have studied for different aspects of language abilities, no studies, to date, have compared them in terms of their word definitional skills. Addressing this gap, the present study examined thirty-six children with DLD, or DD or typically developing (TD) age-matched children. All participants were tested on their expressive vocabulary, non-verbal abilities and on their definitional skills. In the definitional task they had to define 16 words (8 nouns, 4 verbs, and 4 adjectives; simple vs. compound, abstract vs. concrete) orally. Deﬁnitions were evaluated on both content and form. Results have shown that more decontextualized language was used by the TD group than by the two impaired groups and the DD group exhibited the use of more decontextualized language than the DLD group. By contrast, no differences were found among the groups in form. Delving into different word characteristics more demanding were found to be abstract and compound words. DLD group faced more difficulties than the other groups in compound abstract nouns. Fewer differences were found in verbs suggesting that formal definitions of verbs are equally demanding for all groups. Findings suggest that these two disorders have more similarities in most of the categories in terms of the use of decontextualized language. The present study offers new knowledge on the development of definitional skills and indicates that research should investigate them in the light of interrelation of different word characteristics; otherwise the picture we get can be misleading.
Using the Normalized Differential Vegetation Index (NDVI) to Detect Vegetative Change with Remote Sensing and GIS: A Study of the Kumbur River Basin in Kodaikanal Taluk, Dindigul District
Authors: Ramanujam Mahesh , Rangasamy Neelakantan , Rathinam Anbalagan , Veeraiyan Padmanaban 
Published: October 2022

Land use exercises also ultimately affect land cover spatially and in the short term. The primary consideration responsible for land cover adjustment is to meet the growing needs of an expanding population through the intensification of food crops and the clearing of conventional land cover as forests for food and business activities. Land cover modification also disturbs other characteristics of soil maturity, soil decay, environment, biodiversity, air quality and water systems of the disturbed area. Innovating remote sensing and GIS has been developed as a suitable instrument to examine the land use and land cover adjustment of the area at spatial and transient scale. In this survey, the NDVI-based team demonstrated a remarkable change in land cover from 2009 to 2016. A large change was observed in forest cover, where approximately (3.34%) of the forest was degraded between 2009 and 2016.
Particular Approaches to the System of International Humanitarian Law Special Principles: Substance and Evolution
Authors: Yastrebova A. Yu. 
Published: October 2022

INTRODUCTION. The list and the contents of branch (special) principles of IHL are considered to be a current subject of study. Along with the traditional legal approaches, the study forward additional theoretical arguments to include the environmental protection and the responsibility of officials and militaries for war crimes in the system of IHL principles. Besidesthat, it is obvious that the record of IHL prohibitions to belligerents as general international legal rules to conduct hostilities, is refined. MATERIALS AND METHODS. The above study is based both on scientific researches of Russian and foreign authors in the field of IHL and analysis of international legal acts on universal level. Methodological basis of research includes general scientific methods (analysis and synthesis, induction and deduction, modeling and systematization) and special legal methods (legal comparativistics, formal legal). RESEARCH RESULTS. Completed systematization of IHL principles shows combination of different legal concepts, either of which has a certain scientific value. It looks important to summarize the international legal sources and trends taking place in UN system in order to expand the list of the mentioned principles. DISCUSSION AND CONCLUSIONS. In frames of this study the author is proposing the impartial assessments of established scientific approaches to definition and contents of IHL branch (special) principles. Both the forms of international legal cooperation of states to create an institution of responsibility for war crimes and the results of Nuremberg military tribunal regarding prevention of IHL violations are examined separately. The complimentary legal grounds of modern international courts functioning are determined by combination of national and interstate jurisdiction in the above field.
High optical correction system based 800x600 analog spatial light modulator
Authors: Bida Falah A. , Salman Muayad Hanoon , Naser Hayder A. 
Published: October 2022

In this work, a modern optical system based on modulation technique is constructed to achieve the retrieval of optical defects and distortions of the images behind dark barriers. A 800x600 analog spatial light modulator (SLM) is used in this technique with a 632.8nm He-Ne laser, a circular metallic mesh (CMM) is imaged and disturbed and then dealing with our system. The SLM was confirmed for irregularity improvement such as variable diffracted optical element (DOE) control. The obtained results showed that the effect of distortion has been treated and reduced to be minimum by controlling phase and amplitude modulation of the scattered wave front utilizing the SLM. The obtained images showed identical to the original image with limitation in the intensity distribution due to the pixelated structure of SLM. This technique represents the most appropriate solution to the problem of dispersion in images with the lowest costs and best results. The most important applications of this technology are the ability of providing high-resolution imaging where viewing through a deviant medium is inevitable.
Raman Scattering Enhancement by silver Nanostructures Prepared by Electrical Exploding Wire Technique
Authors: Moaen FatimaFatimah Jumaah , Humud Hammad R. 
Published: October 2022

This project aims to fabricate nanostructures (AgNPS) using the electrical exploding wire (EEW) technique using Rhodamine 6G dye as the probe molecule, investigate the effect of AgNPS on the absorption spectra and surface-enhanced Raman scattering (SERS) activities, and advance using porous silicon as an active substrate for surface-enhanced Raman scattering (SERS). X-Ray diffraction (XRD) was used to investigate the structural properties of the nanostructures (AgNPs). Field emission scanning electron microscopy (FE-SEM) was used to investigate surface morphology. A double beam UV-Vis Spectrophotometer was used to analyze the mixed R6G laser dye(of concentration 1x M) absorption spectra with the nanostructures AgNPS (of concentration 24x M). A sunshine Raman microscope device (the objective lens used was (50x)). was used to analyze R6G combined with nanostructures Raman spectra. All samples have shown SERS activity that increased with increasing the hot spots. The SERS enhancement factor for R6G dye(of 1x10-6 M concentration) when mixed with (AgNPS) nanostructures has reached to(2.48 x 106) and the lowest detection limit reached to (1 x 10-14 M) at the wave number (1652 cm-1) using excited laser source (λexc. = 532nm)
The Effect of Cold Plasma on pH, Creatine, and the Concentration of the Most Trace Elements in Human's Nails by Using X-ray Fluorescent Method
Authors: Muryoush Atheer Q. 
Published: October 2022

The aim of this study is to determine the effect of cold plasma on nails pH, creatine levels and the accumulative of some trace elements in humans nails. Creatine levels in the blood, as well as pH and trace elements, were measured before and after (1, 2) months of plasma exposure in both gender (men and women) between the ages of 22 and 25 years. Nails are exposed to cold plasma with a voltage of (175 volts) and (2 gas flow). After one month of exposure, there was no significant change in the levels of all parameters, but after 2 months, the concentration of creatine and pH had reached a near- neutral value. In both men and women, calcium concentration increased and showed a positive response to cold plasma, while the vanadium element concentration did not change over time and remained stable at (7.3×10-4). The results clearly suggest that men respond more than women. The best results were obtained after two-month period of exposure.
Effect of Urban Expansion Indices Change by (R.S.) on Height of Convective Radix Layer around Baghdad Airport (Iraq)
Authors: Hassoon Ahmed F. , Ibraheem Nagham T. 
Published: October 2022

Change in structure of land surface can affect atmospheric boundary layer and formation of internal boundary layer. This will change shear stresses and turbulent boundary layer. Change in low level wind shear and turbulent can affect air craft performance and has potentially adverse effects on flight safety during landing and taking-off stages. In this study, change in land area around Baghdad Airport and its effects on structure of boundary layer and radix layer through summer season (July from years 1985 and 2014) is examined. The examination is done through atmospheric data of radiosonde (at altitude more than 1500 m) and remote sensing by Landsat 5 and 8 images (circular region around airport has radius 3.250 km and the airport is considered the center of this circle). From analysis of hourly wind speed and temperature profile with height observed by radiosonde, change in convective radix layer can be determined at this period resulted from change structure of boundary layer depending on characteristic of landcover used in supervised classification. Building area increases from 18% in 1985 to 41% in 2014. These results enforced by positive values of built up index BI, that showed a decreases in 2014. All these elements changed convective radix layer from less than 500 m in summer 1985 to more than 700 m. There is a large fluctuation in radix layer height depended on convective and friction velocity at 2014 data. Thus indirect change in structure of convective layer will affect navigation movement of Baghdad International Airport.
The Prevalence of Integron Classes Genes Among A. Baumannii Isolates
Authors: Mahmood Suhad S 
Published: October 2022

Acinetobacter baumannii has been recently classified as a major threat to public health because it has resistant to almost all antibiotics and there are many reasons that are responsible for conferring this feature to A. baumannii. One of these reasons is integrons so in this study we show the role of the integrons in providing resistance to some antibiotics. A number of 60 isolates were collected from different clinical sources of patients who were admitted to Baghdad hospitals and all isolates were diagnosed using biochemical tests and confirmed using Chrom-ager culture media, and Vitek 2 compact system. The antibiotic susceptibility test was determined during this study using Kirby-Bauer method and the results of susceptibility demonstrate that these bacteria are responsible for providing resistance to Amikacin, Trimethoprim, Piperacillin, Cefepime, Tetracycline, Ampicillin-sulbactam, Imipenem, and levofloxacin. All isolates show high resistance to trimethoprim and low resistance to tetracycline. The presence of integrons in A. baumannii was detected using conventional polymerase chain reactions. The results showed integron class I was found in all 60 isolates with a percentage (100%) while integron class II was found only in 7 isolates with a percentage (11.6%) and the results of detection showed integron class III are not found in the examined isolates. This study conclude that all A. baumnnii isolates had the strongest resistance to various antibiotics, and the class 1 integron appeared to be the most dominant class among class II and III .
Investigate and Prepare silver Nano Particles Using Jet Plasma
Authors: Noori Aiyah S. , Aadim Kadhim A. , Hussein Alyaa H. 
Published: October 2022

Nano- particles (Ag NPs) are synthesized by using plasma Jet argon gas. The prepared Ag NPs are characterized by Atomic Absorption Spectroscopy (AAS) The measure was performed for different time exposuring 15,30,45 and 60 sec. The results shows the low concentration of nano-silver time expose (15 sec) and very) and high concentration at 60 sec. The UV-VIS spectrometer for nano-silver different time exsposuring to plasma, shows the Surface Plasmon Resonance (SPR) appeared around 419 nm, and the energy gab is 4.1 eV for the 15 second exposure and 1.6eV for 60 second exposure. The Scanning Probe Microscope (SPM) is used to identify the characterization of silver nanoparticles, the average diameter of nano-silver for 15 second exposure is equal to 69.00 nm, for 60 second exposure the average is equal to 54.87 nm
The Influence of CeO2 Concentration on Some Physical Properties of Y2O3 Thin Films
Authors: Karem Ikram Kamel abd , Hamdan Suhad A. 
Published: October 2022

Thin films of pure yttrium oxide (Y2O3) and doped with cerium oxide (CeO2) were prepared by the chemical spray pyrolysis(CSP)method. The structural, optical and electrical properties of the prepared films were investigated. The analysis of X-ray diffraction (XRD) thin films revealed that the undoped and doped Y2O3 were amorphous with a broad hump around 27o and narrow humps around 48o and 62o for all samples. Except for the Y2O3:6wt.%CeO2 thin film, all had signal preferential orientation along the (100) plane at 2θ=12.71o which belongs to CeO2, Field emission scanning electron microscopic (FE-SEM) images confirmed the formation of the nanosized particles which resembles circles and others revealed rods and balls shape. UV-Vis spectra study showed peak absorption at a wavelength of 305 nm, with blue shift due to quantum confinement, and this also happened for the doped films, with direct energy band gaps. The photoluminescence spectra (PL) of undoped Y2O3 and doped thin films showed an emission peak at 365 nm at the same wavelength of all the prepared samples with a slight difference. All prepared films show three activation energies except Y2O3:6wt.%CeO2 film has two activation energies. From I-V characteristic curves, the prepared films have Schottky behavior except Y2O3:6wt.%CeO2 film, which displayed ohmic behavior. Y2O3:6wt.%CeO2 fabricated device revealed good photosensitivity for VIS and IR wavelength.
Spectroscopic Diagnosis of Arc Carbon and Magnesium Plasma
Authors: Hussein Nada K. , Kadhem S. J. 
Published: October 2022

This research aims to investigate parameters for magnesium (Mg) carbon (C), and carbon/magnesium plasma produced by the exploding electrical wire (EEW) technique. In this work, C and Mg nanoparticles were synthesized. The plasma spectra with three different current values (50, 75 and 100A) were recorded using optical emission spectroscopy (OES). The plasma electron temperature (Te), electron density (ne), plasma frequency (fp), Debye length (ℷD), and Debye number (ND) provided by arc discharge plasma were calculated. Boltzmann plots were used to calculate the electron temperature (Te); electron density (ne) was calculated by Stark broadening . The results showed that the electron temperature and electron density increased with the increase of current. For carbon plasma, Te increased from (1.243 to 1.533) eV, and ne increased from (8.762 to 9.857) cm-3. Te for magnesium plasma increased from (0.508 to 0.724)eV and ne increased from(6.700 to 10.420) cm-3. When the magnesium strip was exploded in carbon suspension, Te increased from (0.744 to 0.851) eV, and electron density was raised from (5.738 to 9.304)cm-3.