bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive assessment, review, and comparison of AI models for solar irradiance prediction based on different time/estimation intervals
Authors: Bamisile Olusola , Cai Dongsheng , Oluwasanmi Ariyo , Ejiyi Chukwuebuka , Ukwuoma Chiagoziem C. , Ojo Oluwasegun , Mukhtar Mustapha , Huang Qi 
Published: June 2022

AbstractSolar energy-based technologies have developed rapidly in recent years, however, the inability to appropriately estimate solar energy resources is still a major drawback for these technologies. In this study, eight different artificial intelligence (AI) models namely; convolutional neural network (CNN), artificial neural network (ANN), long short-term memory recurrent model (LSTM), eXtreme gradient boost algorithm (XG Boost), multiple linear regression (MLR), polynomial regression (PLR), decision tree regression (DTR), and random forest regression (RFR) are designed and compared for solar irradiance prediction. Additionally, two hybrid deep neural network models (ANN-CNN and CNN-LSTM-ANN) are developed in this study for the same task. This study is novel as each of the AI models developed was used to estimate solar irradiance considering different timesteps (hourly, every minute, and daily average). Also, different solar irradiance datasets (from six countries in Africa) measured with various instruments were used to train/test the AI models. With the aim to check if there is a universal AI model for solar irradiance estimation in developing countries, the results of this study show that various AI models are suitable for different solar irradiance estimation tasks. However, XG boost has a consistently high performance for all the case studies and is the best model for 10 of the 13 case studies considered in this paper. The result of this study also shows that the prediction of hourly solar irradiance is more accurate for the models when compared to daily average and minutes timestep. The specific performance of each model for all the case studies is explicated in the paper.
An effective nano drug delivery and combination therapy for the treatment of Tuberculosis
Authors: Sheikhpour Mojgan , Delorme Vincent , Kasaeian Alibakhsh , Amiri Vahid , Masoumi Morteza , Sadeghinia Mohammad , Ebrahimzadeh Nayereh , Maleki Mobina , Pourazar Shahin 
Published: June 2022

AbstractDrug resistance in tuberculosis is exacerbating the threat this disease is posing to human beings. Antibiotics that were once effective against the causative agent, Mycobacterium tuberculosis (Mtb), are now no longer usable against multi- and extensively drug-resistant strains of this pathogen. To address this issue, new drug combinations and novel methods for targeted drug delivery could be of considerable value. In addition, studies have shown that the use of the antidepressant drug fluoxetine, a serotonin reuptake inhibitor, can be useful in the treatment of infectious diseases, including bacterial infections. In this study, an isoniazid and fluoxetine-conjugated multi-walled carbon nanotube nanofluid were designed to increase drug delivery efficiency alongside eliminating drug resistance in vitro. The prepared nanofluid was tested against Mtb. Expression levels of inhA and katG mRNAs were detected by Real-time PCR. ELISA was applied to measure levels of cytokine secretion (TNF-α, and IL-6) from infected macrophages treated with the nano delivery system. The results showed that these nano-drug delivery systems are effective for fluoxetine at far lower doses than for free drugs. Fluoxetine also has an additive effect on the effect of isoniazid, and their concomitant use in the delivery system can have significant effects in treating infection of all clinical strains of Mtb. In addition, it was found that the expression of isoniazid resistance genes, including inhA, katG, and the secretion of cytokines TNFα and IL6 under the influence of this drug delivery system is well regulated. It was shown that the drug conjugation can improve the antibacterial activity of them in all strains and these two drugs have an additive effect on each other both in free and conjugated forms. This nano-drug delivery method combined with host targeted molecules could be a game-changer in the development of a new generation of antibiotics that have high therapeutic efficiencies, low side effects, and the potential to overcome the problem of drug resistance.
Evoked responses to note onsets and phrase boundaries in Mozart's K448
Authors: Feng Yijing , Quon Robert J. , Jobst Barbara C. , Casey Michael A. 
Published: June 2022

AbstractUnderstanding the neural correlates of perception of hierarchical structure in music presents a direct window into auditory organization. To examine the hypothesis that high-level and low-level structures—i.e. phrases and notes—elicit different neural responses, we collected intracranial electroencephalography (iEEG) data from eight subjects during exposure to Mozart’s K448 and directly compared Event-related potentials (ERPs) due to note onsets and those elicited by phrase boundaries. Cluster-level permutation tests revealed that note-onset-related ERPs and phrase-boundary-related ERPs were significantly different at $$-150$$

-
150

, 200, and 450 ms relative to note onset and phrase markers. We also observed increased activity in frontal brain regions when processing phrase boundaries. We relate these observations to (1) a process which syntactically binds notes together hierarchically to form larger phrases; (2) positive emotions induced by successful prediction of forthcoming phrase boundaries and violations of melodic expectations at phrase boundaries.
The role of the diffusion in the predictions of the classical nucleation theory for quasi-real systems differ in dipole moment value
Authors: Koperwas Kajetan , Kaśkosz Filip , Affouard Frederic , Grzybowski Andrzej , Paluch Marian 
Published: June 2022

AbstractIn this paper, we examine the crystallization tendency for two quasi-real systems, which differ exclusively in the dipole moment's value. The main advantage of the studied system is the fact that despite that their structures are entirely identical, they exhibit different physical properties. Hence, the results obtained for one of the proposed model systems cannot be scaled to reproduce the results for another corresponding system, as it can be done for simple model systems, where structural differences are modeled by the different parameters of the intermolecular interactions. Our results show that both examined systems exhibit similar stability behavior below the melting temperature. This finding is contrary to the predictions of the classical nucleation theory, which suggests a significantly higher crystallization tendency for a more polar system. Our studies indicate that the noted discrepancies are caused by the kinetic aspect of the classical nucleation theory, which overestimates the role of diffusion in the nucleation process.
Effective removal of Pb(II) ions using piperazine-modified magnetic graphene oxide nanocomposite; optimization by response surface methodology
Authors: Alboghbeish Mousa , Larki Arash , Saghanezhad Seyyed Jafar 
Published: June 2022

AbstractIn this research, the piperazine-modified magnetic graphene oxide (Pip@MGO) nanocomposite was synthesized and utilized as a nano-adsorbent for the removal of Pb(II) ions from environmental water and wastewater samples. The physicochemical properties of Pip@MGO nanocomposite was characterized by X-ray diffraction analysis (XRD), Field emission scanning electron microscopy (FESEM), Transmission electron microscopy (TEM), Energy-dispersive X-ray spectroscopy (EDAX), Thermo-gravimetric analysis (TGA), Vibrating Sample Magnetometery (VSM) and Fourier-transform infrared spectroscopy (FT-IR) analysis. In this method, the batch removal process were designed by response surface methodology (RSM) based on a central composite design (CCD) model. The results indicated that the highest efficiency of Pb(II) removal was obtained from the quadratic model under optimum conditions of prominent parameters (initial pH 6.0, adsorbent dosage 7 mg, initial concentration of lead 15 mg L−1 and contact time 27.5 min). Adsorption data showed that lead ions uptake on Pip@MGO nanocomposite followed the Langmuir isotherm model equation and pseudo-second order kinetic model. High adsorption capacity (558.2 mg g−1) and easy magnetic separation capability showed that the synthesized Pip@MGO nanocomposite has great potential for the removal of Pb(II) ions from contaminated wastewaters.
Multimodal detection of dopamine by sniffer cells expressing genetically encoded fluorescent sensors
Authors: Klein Herenbrink Carmen , Støier Jonatan Fullerton , Reith William Dalseg , Dagra Abeer , Gregorek Miguel Alejandro Cuadrado , Cola Reto B. , Patriarchi Tommaso , Li Yulong , Tian Lin , Gether Ulrik , Herborg Freja 
Published: June 2022

AbstractDopamine supports locomotor control and higher brain functions such as motivation and learning. Consistently, dopaminergic dysfunction is involved in a spectrum of neurological and neuropsychiatric diseases. Detailed data on dopamine dynamics is needed to understand how dopamine signals translate into cellular and behavioral responses, and to uncover pathological disturbances in dopamine-related diseases. Genetically encoded fluorescent dopamine sensors have recently enabled unprecedented monitoring of dopamine dynamics in vivo. However, these sensors’ utility for in vitro and ex vivo assays remains unexplored. Here, we present a blueprint for making dopamine sniffer cells for multimodal dopamine detection. We generated sniffer cell lines with inducible expression of seven different dopamine sensors and perform a head-to-head comparison of sensor properties to guide users in sensor selection. In proof-of-principle experiments, we apply the sniffer cells to record endogenous dopamine release from cultured neurons and striatal slices, and for determining tissue dopamine content. Furthermore, we use the sniffer cells to measure dopamine uptake and release via the dopamine transporter as a radiotracer free, high-throughput alternative to electrochemical- and radiotracer-based assays. Importantly, the sniffer cell framework can readily be applied to the growing list of genetically encoded fluorescent neurotransmitter sensors.
The phylodynamics of SARS-CoV-2 during 2020 in Finland
Authors: Truong Nguyen Phuoc , Kant Ravi , Van den Broeck Frederik , Suvanto Maija T. , Alburkat Hussein , Virtanen Jenni , Ahvenainen Ella , Castren Robert , Hong Samuel L. , Baele Guy , Ahava Maarit J. , Jarva Hanna , Jokiranta Suvi Tuulia , Kallio-Kokko Hannimari , Kekäläinen Eliisa , Kirjavainen Vesa , Kortela Elisa , Kurkela Satu , Lappalainen Maija , Liimatainen Hanna , Suchard Marc A. , Hannula Sari , Ellonen Pekka , Sironen Tarja , Lemey Philippe , Vapalahti Olli , Smura Teemu 
Published: June 2022

Abstract
Background
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of infections and fatalities globally since its emergence in late 2019. The virus was first detected in Finland in January 2020, after which it rapidly spread among the populace in spring. However, compared to other European nations, Finland has had a low incidence of SARS-CoV-2. To gain insight into the origins and turnover of SARS-CoV-2 lineages circulating in Finland in 2020, we investigated the phylogeographic and -dynamic history of the virus.

Methods
The origins of SARS-CoV-2 introductions were inferred via Travel-aware Bayesian time-measured phylogeographic analyses. Sequences for the analyses included virus genomes belonging to the B.1 lineage and with the D614G mutation from countries of likely origin, which were determined utilizing Google mobility data. We collected all available sequences from spring and fall peaks to study lineage dynamics.

Results
We observed rapid turnover among Finnish lineages during this period. Clade 20C became the most prevalent among sequenced cases and was replaced by other strains in fall 2020. Bayesian phylogeographic reconstructions suggested 42 independent introductions into Finland during spring 2020, mainly from Italy, Austria, and Spain.

Conclusions
A single introduction from Spain might have seeded one-third of cases in Finland during spring in 2020. The investigations of the original introductions of SARS-CoV-2 to Finland during the early stages of the pandemic and of the subsequent lineage dynamics could be utilized to assess the role of transboundary movements and the effects of early intervention and public health measures.
GaiaData Release 3
Authors: Blomme R. , Frémat Y. , Sartoretti P. , Guerrier A. , Panuzzo P. , Katz D. , Seabroke G. M. , Thévenin F. , Cropper M. , Benson K. , Damerdji Y. , Haigron R. , Marchal O. , Smith M. , Baker S. , Chemin L. , David M. , Dolding C. , Gosset E. , Janßen K. , Jasniewicz G. , Lobel A. , Plum G. , Samaras N. , Snaith O. , Soubiran C. , Vanel O. , Zwitter T. , Brouillet N. , Caffau E. , Crifo F. , Fabre C. , Fragkoudi F. , Huckle H. E. , Jean-Antoine Piccolo A. , Lasne Y. , Leclerc N. , Mastrobuono-Battisti A. , Royer F. , Viala Y. , Zorec J. 
Published: June 2022

Context.The secondGaiadata release, DR2, contained radial velocities of stars with effective temperatures up toTeff = 6900 K. The third data release,GaiaDR3, extends this up toTeff = 14 500 K.Aims.We derive the radial velocities for hot stars (i.e., in theTeff = 6900 − 14 500 K range) from data obtained with the Radial Velocity Spectrometer (RVS) on boardGaia.Methods.The radial velocities were determined by the standard technique of measuring the Doppler shift of a template spectrum that was compared to the observed spectrum. The RVS wavelength range is very limited. The proximity to and systematic blueward offset of the calcium infrared triplet to the hydrogen Paschen lines in hot stars can result in a systematic offset in radial velocity. For the hot stars, we developed a specific code to improve the selection of the template spectrum, thereby avoiding this systematic offset.Results.With the improved code, and with the correction we propose to the DR3 archive radial velocities, we obtain values that agree with reference values to within 3 km s−1(in median). Because of the required S/N for applying the improved code, the hot star radial velocities in DR3 are mostly limited to stars with a magnitude in the RVS wavelength band ≤12 mag.
Procédé plastronique Electronique Structurelle Surmoulée (ESS, IME – In Mold Electronics) dans un projet de mise en œuvre pratique
Authors: Lombard Ph , Gerges T. , Charmeau J.-Y. , Allard B. , Cabrera M. 
Published: June 2022

Au croisement des métiers de la plasturgie et de l’électronique, la plastronique constitue un nouveau champ technologique et ouvre de nouvelles opportunités pour miniaturiser et intégrer de manière optimale des systèmes électroniques aux objets polymères en trois dimensions – 3D. De nouveaux procédés émergent et trouvent des applications innovantes dans de nombreux secteurs d’activité.
A cet égard, l’intérêt des industriels et des étudiants est en pleine croissance. Il convient de répondre à ces attentes avec un éventail de formations appropriées et de les accompagner par des enseignements spécifiques que nous souhaitons originaux.
Cet article introduit la plastronique et plus particulièrement le procédé plastronique 3D appelé Electronique Structurelle Surmoulée (ESS, IME – In Mold Electronics). Il présente également les étapes du travail expérimental et pratique de mise en oeuvre d’un projet étudiant. L’objectif est de s’adapter aux niveaux des apprenants et aux objectifs pédagogiques désirés. Il s’agit de réaliser, dans son ensemble, un dispositif fonctionnel concret suscitant l’éveille et l’intérêt des apprenants.
Does i-scan improve adenoma detection rate compared to high-definition colonoscopy? A systematic review and meta-analysis
Authors: Aziz Muhammad , Ahmed Zohaib , Haghbin Hossein , Pervez Asad , Goyal Hemant , Kamal Faisal , Kobeissy Abdallah , Nawras Ali , Adler Douglas G. 
Published: June 2022

Abstract
Background and study aims Recent studies evaluated the impact of i-scan in improving the adenoma detection rate (ADR) compared to high-definition (HD) colonoscopy. We aimed to systematically review and analyze the impact of this technique.
Methods A thorough search of the following databases was undertaken: PubMed/Medline, EMBASE, Cochrane and Web of Science. Full-text RCTs and cohort studies directly comparing i-scan and HD colonoscopy were deemed eligible for inclusion. Dichotomous outcomes were pooled and compared using random effects model and DerSimonian-Laird approach. For each outcome, relative risk (RR), 95 % confidence interval (CI), and P value was generated. P < 0.05 was considered statistically significant.
Results A total of five studies with six arms were included in this analysis. A total of 2620 patients (mean age 58.6 ± 7.2 years and female proportion 44.8 %) completed the study and were included in our analysis. ADR was significantly higher with any i-scan (RR: 1.20, [CI: 1.06–1.34], P = 0.003) compared to HD colonoscopy. Subgroup analysis demonstrated that ADR was significantly higher using i-scan with surface and contrast enhancement only (RR: 1.25, [CI: 1.07–1.47], P = 0.004).
Conclusions i-scan has the potential to increase ADR using the surface and contrast enhancement method. Future studies evaluating other outcomes of interest such as proximal adenomas and serrated lesions are warranted.
Anti-reflux mucosectomy for refractory gastroesophageal reflux disease: a systematic review and meta-analysis
Authors: Garg Rajat , Mohammed Abdul , Singh Amandeep , Schleicher Mary , Thota Prashanthi N. , Rustagi Tarun , Sanaka Madhusudhan R 
Published: June 2022

Abstract
Background and study aims Anti-reflux mucosectomy (ARMS) is an emerging endoscopic treatment for refractory gastroesophageal reflux disease (GERD). We conducted a systematic review and meta-analysis to evaluate the safety and efficacy ARMS in refractory GERD.
Methods A comprehensive search of multiple databases (through March 2020) was performed to identify studies that reported outcomes of ARMS for refractory GERD. Outcomes assessed included technical success, clinical response, and adverse events (AEs). Clinical response was defined as discontinuation (complete) or reduction (partial) of proton pump inhibitors post-ARMS at follow up.
Results A total of 307 patients (mean age 46.9 [8.1] years, 41.5 % females) were included from 10 studies. The technical success and clinical response rates were 97.7 % (95 % confidence interval [CI], 94.6–99.0) and 80.1 % (95 % CI, 61.6–91.0), respectively. The pooled rate of complete and partial clinical response was 65.3 % (95 % CI, 51.4–77.0) and 21.5 % (95 % CI, 14.2–31.2), respectively. The rate of AEs was 17.2 % (95 % CI, 13.1–22.2) with most common AE being dysphagia/esophageal stricture followed by bleeding with rates of 11.4 % and 5.0 %, respectively. GERD health-related quality of life (GERD-HRQL) (mean difference [MD] = 14.9, P < 0.001), GERD questionnaire (GERD-Q) (MD = 4.85, P < 0.001) and mean acid exposure time (MD = 2.39, P = 0.01) decreased significantly post-ARMS as compared to pre-procedure. There was no difference in terms of clinical response and AEs between ARMS and ARMS with banding on subgroup analysis.
Conclusions ARMS is a safe and effective procedure for treatment of refractory GERD with high rates of clinical response, acceptable safety profile and significant improvement in GERD-related quality of life. Prospective studies are needed to validate our findings.
Update Mammakarzinom 2021 Teil 4 – Prävention und frühe Krankheitsstadien
Authors: Thomssen Christoph , Fehm Tanja N. , Stickeler Elmar , Fasching Peter A. , Janni Wolfgang , Kolberg-Liedtke Cornelia , Kolberg Hans-Christian , Lüftner Diana , Müller Volkmar , Schütz Florian , Belleville Erik , Bader Simon , Untch Michael , Welslau Manfred , Thill Marc , Hartkopf Andreas D. , Tesch Hans , Ditsch Nina , Lux Michael P. , Wöckel Achim , Aktas Bahriye , Schneeweiss Andreas , Würstlein Rachel 
Published: June 2022

ZusammenfassungIm vergangenen Jahr wurden für viele Patientinnen mit Mammakarzinom in frühem Krankheitsstadium neue und effektive Optionen für eine weitere Verbesserung der Behandlungsergebnisse gezeigt. Für Patientinnen mit hormonrezeptorpositiver Erkrankung zeigte sich ein signifikanter Zusatzeffekt durch den Einsatz des CDK4/6-Inhibitors Abemaciclib zusätzlich zur endokrinen adjuvanten Therapie. Bei triple-negativer Erkrankung wurden Daten für 2 Therapieprinzipien gezeigt. Patientinnen mit fortgeschrittener Erkrankung (Stadium 2 und 3) profitieren von dem neoadjuvanten Einsatz des Immuncheckpoint-Inhibitors Pembrolizumab unabhängig von der PD‑L1-Expression in Kombination mit einer Standardchemotherapie. Bei BRCA1- oder BRCA2-Mutation wurde ein eindrucksvoller Benefit durch den Einsatz des PARP-Inhibitors Olaparib gezeigt, wenn die neoadjuvante Therapie nicht zur gewünschten Remission geführt hat. Weitere Daten betreffen translationale Fragestellungen beim HER2-positiven Mammakarzinom sowie neoadjuvante Therapieansätze mit dem oralen SERD Giredestrant und dem PARP-Inhibitor Talazoparib. In dieser Übersichtsarbeit werden die Ergebnisse der wichtigsten Studienergebnisse dieses Jahres vorgestellt und bewertet.
Hämodynamisch relevante intrathorakale Blutung nach CPR: Fallbericht über eine reanimationsassoziierte Verletzung von Interkostalarterien mit Notwendigkeit einer arteriellen
Transkatheter-Embolisation
Authors: Obermaier Manuel , Do Thuy Duong 
Published: June 2022

ZusammenfassungTraumata mit Rippen(serien)- und Sternumfrakturen sind häufige Folgen einer kardiopulmonalen Reanimation. Wir stellen einen Fall vor, bei dem es infolge der Thoraxkompressionen zu einer
Rippenserienfraktur mit hämodynamisch relevanter und transfusionspflichtiger Blutung aus 3 Interkostalarterien kam. Der Befund wurde mittels interventionell-radiologischer Coilembolisation
therapiert. Nach kardiopulmonaler Reanimation sollten, insbesondere bei hämodynamischer Instabilität, Traumata in Betracht gezogen und aktiv gesucht bzw. ausgeschlossen werden.
Rubidium frequency standard with pulsed optical pumping and frequency instability of 2.5 × 10−13τ
− 1/2
Authors: Baryshev V.N. , Osipenko G.V. , Novoselov A.V. , Sukhoverskaya A.G. , Boyko A.I. , Aleynikov M.S. 
Published: June 2022

Abstract
The work is dedicated to the further development of a compact quantum frequency standard based on a rubidium gas cell with a mixture of buffer gases. The results of frequency measurements and analysis of short-term frequency instability obtained on a laboratory prototype of a microwave rubidium atomic frequency standard (RAFS) with pulsed optical pumping (POP) are presented. The main in magnitude contributions to the overall frequency instability of the RAFS with POP are estimated. Short-term frequency instability expressed in terms of the Allan deviation and measured at averaging times τ up to several tens of seconds, σy
(τ) = 2.5×10−13
τ
−1/2, coincides satisfactorily with the calculated value of σy
(τ) = 2.1×10−13
τ
−1/2.
Stimulated low-frequency Raman light scattering in systems of nano- and submicron-sized particles
Authors: Karpov M.A. , Kudryavtseva A.D. , Shevchenko M.A. , Tcherniega N.V. , Umanskaya S.F. 
Published: June 2022

Abstract
We present a brief review of experimental work on the investigation of stimulated low-frequency Raman scattering of light in systems of submicron and nanosized particles of various physical nature.
Specificity of micro- and nanoproducts of titanium laser ablation in pure water
Authors: Borodina T.I. , Val’yano G.E. , Malikov M.M. 
Published: June 2022

Abstract
Laser ablation of titanium in distilled water at high and low power densities of copper vapour laser beam in the focal spot on a target surface is experimentally studied. Ablation regimes with different pulsed energy inputs and target irradiation times are investigated. The morphology and elemental and phase compositions of micro- and nanoaggregates obtained in different irradiation regimes are studied using electron microscopy, X-ray diffraction analysis, and Raman spectroscopy. The ablation products are found to be practically totally in the X-ray amorphous state.