bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of Commercial SaaS Solutions in Swedish Public Sector Organisations under Unknown Contract Terms
Authors: Lundell Björn , Gamalielsson Jonas , Katz Andrew , Lindroth Mathias 
Published: August 2022

AbstractLawful and appropriate use of cloud-based globally provided Software-as-a-Service (SaaS) solutions by a public sector organisation (PSO) for data processing and maintenance of digital assets presupposes an investigation of all relevant contract terms. Having obtained, analysed, and filed all relevant contract terms when using a SaaS solution is a prerequisite for good administration. Identifying and obtaining all relevant contract terms for a SaaS solution involves significant obstacles which in practice may be impossible to overcome for each PSO. This paper addresses how PSOs investigate contract terms prior to adoption, and why PSOs use a globally provided SaaS solution without having identified and obtained all relevant contract terms. Through a review of responses to questions and public documents from Swedish PSOs we analysed how each PSO had investigated contract terms and licences for the Microsoft 365 (M365) solution prior to adoption and use of the solution in each PSO. We find that no PSO had investigated all relevant contract terms prior to use of M365, which implies that each PSO uses M365 under unknown contract terms. Further, we find that all PSOs use M365 for data processing of its digital assets under unknown contract terms and that each PSO has significant dependence and trust in its supplier.
Conceptual Framework: Sociological Neo-Institutionalism, Legitimacy, and Public Relations
Authors: Marschlich Sarah 
Published: August 2022

AbstractIn order to examine the role of corporate diplomacy in building organizational legitimacy, the current research builds on a theoretical and conceptual framework consisting of sociological neo-institutionalism, legitimacy and media frames, and public relations theory. In this chapter, the theoretical approaches and central constructs will be introduced, defined, and discussed.
Corporate Diplomacy at the Intersection of Public Relations and Public Diplomacy
Authors: Marschlich Sarah 
Published: August 2022

AbstractSince the concept of corporate diplomacy is at the core of this dissertation, this chapter will offer an extensive review of the previous literature on corporate diplomacy to derive a concise definition of corporate diplomacy, guiding this thesis. Corporate diplomacy originates to a large extent from public diplomacy. Therefore, this chapter will first introduce public diplomacy by outlining significant conceptualizations of the term and comparing public diplomacy with public relations to distinguish the two fields from each other.
State of Research: Previous Findings on Corporate Diplomacy, the Media, and Organizational Legitimacy
Authors: Marschlich Sarah 
Published: August 2022

ZusammenfassungNow that this thesis has introduced the theoretical framework and discussed the related main concepts of corporate diplomacy, public relations, legitimacy and the role of the media, and institutional linkages, the fourth chapter reviews previous research on these constructs. The chapter firstly presents previous findings on corporate diplomacy and secondly on public relations as a legitimation strategy. Subsequently, previous research on the media’s role in gaining legitimacy and institutional linkages in the organizational legitimation process are reviewed.
Study Context: The Case of the UAE
Authors: Marschlich Sarah 
Published: August 2022

ZusammenfassungThis chapter portrays the UAE’s particularities in terms of political, economic, cultural, and media systems are presented and linked to public relations and corporate diplomacy. By outlining the features of the economic, political, and media systems as well as cultural characteristics and discussing these in the context of public relations and corporate diplomacy, this chapter provides a comprehensive contextualization of this thesis.
Method
Authors: Marschlich Sarah 
Published: August 2022

ZusammenfassungFour different research questions guide this research project. A mixed-method research design with qualitative and quantitative empirical methods was chosen since it enables an in-depth understanding of the phenomenon of corporate diplomacy. This thesis used a triangulation of methods to study corporate diplomacy on the organizational, media, and general audience levels. This chapter presents each method and the procedure of every study in detail.
Conclusion
Authors: Marschlich Sarah 
Published: August 2022

AbstractIn today’s world, MNCs not only have great financial power but an immense impact on the communities in the host countries where they operate. In many cases, MNCs have an even greater effect on society than the local government does. However, organizations are constantly observed and scrutinized by different actors in their environment, including the media, NGOs, and governments in their home country as well as in their host countries. A summary of the conducted studies is provided hereafter to answer the research questions presented at the beginning of this thesis.
Academic Practices: Current Strategies to Attract and Retain Indigenous Higher Degree by Research Students in Australia
Authors: Anderson Peter , Blue Levon , Pham Thu , Saward Melanie 
Published: August 2022

AbstractThe number of Indigenous higher degree by research (HDR) students has increased steadily over the past decade. Support for Indigenous students from the Australian government, universities and Indigenous Support Units has been documented in Australian higher education. Unfortunately, a range of barriers continue to hinder Indigenous HDR students to completion in their research journey. Presented in this book chapter is the literature review of barriers, including lack of academic skill set and research skills to pursue a research degree program, lack of social and academic support for Indigenous HDR students, the student—supervisor relationship issues and challenges relating to health, family and community responsibilities. Simultaneously, our review identified current strategies and initiatives to retain Indigenous HDR students in their research degree programs and to support them to completion, highlighting the roles of the Indigenous Postgraduate Support Officer and the National Indigenous Research and Knowledges Network. This review, we suggest, should move further to analyse the effectiveness of current strategies and initiatives provided for Indigenous HDR students in detail to inform Indigenous students of the available support resources and how to access to these resources.
Capacity-Building Support for Indigenous HDR Students via the National Indigenous Research and Knowledges Network
Authors: Anderson Peter , Blue Levon , Pham Thu , Saward Melanie 
Published: August 2022

AbstractSince 2013, Indigenous higher degree by research (HDR) students have had an opportunity to participate in capacity-building workshops conducted by the National Indigenous Research and Knowledges Network (NIRAKN). The workshops included basic information about completing a research degree, including how to navigate academia, how to read and write critically and an introduction to Indigenous research methodologies. In this chapter, an overview of what NIRAKN set out to achieve and what has been accomplished is discussed. Evaluation forms completed by Indigenous HDR students (n = 78) who attended capacity-building workshops were analysed to understand what students found to be beneficial when participating in NIRAKN events. Here, we share the findings and offer insights into ways higher education institutions can support Indigenous HDR students in the successful completion of their degrees.
The Role of Agency in Higher Education: Acquiring Academic Capital
Authors: Anderson Peter , Blue Levon , Pham Thu , Saward Melanie 
Published: August 2022

AbstractIndigenous higher degree by research (HDR) students navigating higher education institutions continue to face additional challenges that are not associated with the research degree they are pursuing. Racism continues to be identified as a barrier present in academic settings and society. The impact of racism may affect an individual’s agency and their ability to acquire academic capital. Both agency and academic capital may also influence how an individual is supported throughout their candidature and ultimately become a factor in the success of the HDR student’s research degree. In this chapter, we discuss the role of agency and academic capital among Indigenous HDR students and then connect our findings to how Indigenous HDR students (n = 99) report that agency and/or how academic capital has influenced their experience in higher education. This chapter is also informed by insights from supervisors of Indigenous HDR students (n = 33).
Indigenous Higher Degree by Research Students’ Needs and Experiences
Authors: Anderson Peter , Blue Levon , Pham Thu , Saward Melanie 
Published: August 2022

AbstractThis chapter focuses on the needs and experiences of Indigenous higher degree by research (HDR) students in academia. The study employed qualitative research methods, including group discussions and individual written responses (n = 34) and an online survey (n = 32). The participants were Indigenous HDR students from different disciplinary fields from across Australia who participated in this research during 2018 and 2020. Specifically, this research project explored the students’ needs and experiences during their candidature. We found that the role of supervisors in the students’ HDR journey impacted their sense of agency and their opportunities for mentorship and networking within their discipline. Indigenous HDR student specifically reported the need for: (1) quality supervision; (2) mentoring opportunities; and (3) access to research training. The reported needs bring the spotlight on how increasing retention rates of Indigenous HDR students might be possible.
Intensivpflegerische Versorgung von Patient:innen mit [infarktbedingtem], kardiogenen Schock
Authors: Hermes C. , Ochmann T. ,   Deutsche Gesellschaft für Internistische Intensivmedizin und Notfallmedizin e. V. (DGIIN), Keienburg C. ,   Deutsche Gesellschaft für Fachkrankenpflege und Funktionsdienste e. V. (DGF), Kegel M. ,   Deutsche Gesellschaft Interdisziplinäre Notfall- und Akutmedizin e. V. (DGINA), Schindele D. ,   Deutsche Interdisziplinäre Vereinigung für Intensiv- und Notfallmedizin e. V. (DIVI), Klausmeier J. ,   Deutsche Gesellschaft für Kardiologie – Herz- und Kreislaufforschung e. V. (DGK), Adrigan E. ,   Österreichische Gesellschaft für Internistische und Allgemeine Intensivmedizin und Notfallmedizin e. V. (ÖGIAIN)
Published: August 2022

Zusammenfassung
Hintergrund
Herz-Kreislauf-Erkrankungen und der (infarktbedingte) kardiogene Schock zählen zu den häufigsten Todesursachen in Deutschland. Eine adäquate klinische Versorgung stellt die Krankenhäuser oft vor große Herausforderungen. Die komplexe Versorgung der Patient:innen im multiprofessionellen Team stellt hohe Anforderungen an alle am Versorgungsprozess Beteiligten. Da besonders die Pflegefachpersonen im engen Patient:innenkontakt stehen und die Therapie maßgeblich mitgestalten und steuern, ist eine nationale, (intensiv)pflegerische Leitlinie dringend erforderlich.

Methoden
Im Rahmen des Leitlinienprogramms der Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften e. V. (AWMF) wurde unter Beteiligung von sechs Fachgesellschaften eine S1-Leitlinie entwickelt und im Mai 2022 veröffentlicht. Die Leitliniengruppe legte relevante Themengebiete fest, die durch eine systematische Literaturrecherche in Peer-Review-Journalen bearbeitet wurden. Aufgrund der S1-Klassifikation wurde keine gesonderte Evidenzaufbereitung vorgenommen. Zur Einstufung der Empfehlungen wurde ein formaler Konsensbildungsprozess durchgeführt.

Ergebnisse
Die Leitlinie enthält 36 Empfehlungen, die sich von der pflegerischen Versorgung in der Zentralen Notaufnahme über das Herzkatheterlabor und die Intensivstation bis zur Nachsorge erstrecken. Zudem werden Empfehlungen zu notwendigen Qualifikationen und strukturellen Voraussetzungen in den jeweiligen Bereichen getroffen, um einen qualitativ hochwertigen (pflegerischen) Versorgungsprozess zu gewährleisten.

Fazit
Dies ist die erste nationale intensivpflegerische Leitlinie. Sie richtet sich an Pflegefachpersonen, die in die Versorgung von Patient:innen mit (infarktbedingtem) kardiogenen Schock involviert sind. Die Leitlinie ist bis zum 30.12.2026 gültig.
Conceptual design of an innovative gas–gas ceramic compact heat exchanger suitable for high temperature applications
Authors: Zavattoni Simone A. , Cornolti Luca , Puragliesi Riccardo , Arrivabeni Edoardo , Ortona Alberto , Barbato Maurizio C. 
Published: August 2022

AbstractThe development of an innovative and highly efficient heat exchanger (HE) solution for gas–gas heat recovery is one of the major objectives of the HYDROSOL-beyond project which aims at enhancing the process efficiency for producing hydrogen from water dissociation with concentrated sunlight. Because of the very high temperature level of the process (up to 1400 °C), an innovative ceramic HE design was proposed with an integrated lattice structure, as secondary surface, to maximize the heat transfer. To assist the design of the HE, a multiscale approach was adopted: a 1D model based on global correlations was developed and a 3D computational fluid dynamics model of the secondary surfaces were generated. The former was applied to assess the performance of the entire HE; while, the latter was exploited to study in detail the thermo-fluid dynamics behavior of a HE core element and to provide the global correlations to be integrated into the 1D model. In this work, the effect of several parameters and operating conditions, namely, number of channels, number of lattice layers located into each channel, solid material exploited for the HE structure, parting plates thickness, heat transfer fluid velocity, radiation heat transfer and solid material emissivity, on the HE effectiveness are reported and accurately described. Furthermore, based upon the results obtained, guidelines on the HE design to maximize its performance are also provided.
Functional association of NR4A3 downregulation with impaired differentiation in myeloid leukemogenesis
Authors: Lin Shih-Chiang , Yao Chi-Yuan , Hsu Cheng-An , Lin Chien-Ting , Calkins Marcus J. , Kuo Yuan-Yeh , Tang Jih-Luh , Tien Hwei-Fang , Wu Shang-Ju 
Published: August 2022

AbstractThe coincident downregulation of NR4A1 and NR4A3 has been implicated in myeloid leukemogenesis, but it remains unknown how these two genes function in myeloid cells and how their combined downregulation promotes myeloid leukemogenesis. Since NR4A1 abrogation is thought to confer a survival and proliferation advantage to myeloid cells, we hypothesized that downregulation of NR4A3 may have a complementary effect on myeloid cell differentiation. First, we tested the association between differentiation status of leukemic cells and NR4A3 expression using two large clinical datasets from patients with different acute myeloid leukemia (AML) subtypes. The analysis revealed a close association between differentiation status and different subtypes of AML Then, we probed the effects of differentiation-inducing treatments on NR4A3 expression and NR4A3 knockdown on cell differentiation using two myeloid leukemia cell lines. Differentiation-inducing treatments caused upregulation of NR4A3, while NR4A3 knockdown prevented differentiation in both cell lines. The cell culture findings were validated using samples from chronic myeloid leukemia (CML) patients at chronic, accelerated and blastic phases, and in acute promyelocytic leukemia (APL) patients before and after all trans-retinoic acid (ATRA)-based differentiation therapy. Progressive NR4A3 downregulation was coincident with impairments in differentiation in patients during progression to blastic phase of CML, and NR4A3 expression was increased in APL patients treated with ATRA-based differentiating therapy. Together, our findings demonstrate a tight association between impaired differentiation status and NR4A3 downregulation in myeloid leukemias, providing a plausible mechanistic explanation of how myeloid leukemogenesis might occur upon concurrent downregulation of NR4A1 and NR4A3.
Spatiotemporal characterization of cellular tau pathology in the human locus coeruleus–pericoerulear complex by three-dimensional imaging
Authors: Gilvesy Abris , Husen Evelina , Magloczky Zsofia , Mihaly Orsolya , Hortobágyi Tibor , Kanatani Shigeaki , Heinsen Helmut , Renier Nicolas , Hökfelt Tomas , Mulder Jan , Uhlen Mathias , Kovacs Gabor G. , Adori Csaba 
Published: August 2022

AbstractTau pathology of the noradrenergic locus coeruleus (LC) is a hallmark of several age-related neurodegenerative disorders, including Alzheimer’s disease. However, a comprehensive neuropathological examination of the LC is difficult due to its small size and rod-like shape. To investigate the LC cytoarchitecture and tau cytoskeletal pathology in relation to possible propagation patterns of disease-associated tau in an unprecedented large-scale three-dimensional view, we utilized volume immunostaining and optical clearing technology combined with light sheet fluorescence microscopy. We examined AT8+ pathological tau in the LC/pericoerulear region of 20 brains from Braak neurofibrillary tangle (NFT) stage 0–6. We demonstrate an intriguing morphological complexity and heterogeneity of AT8+ cellular structures in the LC, representing various intracellular stages of NFT maturation and their diverse transition forms. We describe novel morphologies of neuronal tau pathology such as AT8+ cells with fine filamentous somatic protrusions or with disintegrating soma. We show that gradual dendritic atrophy is the first morphological sign of the degeneration of tangle-bearing neurons, even preceding axonal lesions. Interestingly, irrespective of the Braak NFT stage, tau pathology is more advanced in the dorsal LC that preferentially projects to vulnerable forebrain regions in Alzheimer’s disease, like the hippocampus or neocortical areas, compared to the ventral LC projecting to the cerebellum and medulla. Moreover, already in the precortical Braak 0 stage, 3D analysis reveals clustering tendency and dendro-dendritic close appositions of AT8+ LC neurons, AT8+ long axons of NFT-bearing cells that join the ascending dorsal noradrenergic bundle after leaving the LC, as well as AT8+ processes of NFT-bearing LC neurons that target the 4th ventricle wall. Our study suggests that the unique cytoarchitecture, comprised of a densely packed and dendritically extensively interconnected neuronal network with long projections, makes the human LC to be an ideal anatomical template for early accumulation and trans-neuronal spreading of hyperphosphorylated tau.
Timing of antenatal steroid administration for imminent preterm birth: results of a prospective observational study in Germany
Authors: Humbeck Charlotte , Jonassen Sinje , Bringewatt Arne , Pervan Mascha , Rody Achim , Bossung Verena 
Published: August 2022

Abstract
Purpose
To evaluate the timing of antenatal steroid administration and associated medical interventions in women with imminent preterm birth.

Methods
We performed a prospective observational study at a single tertiary center in Germany from September 2018 to August 2019. We included pregnant women who received antenatal steroids for imminent preterm birth and evaluated the interval from administration to birth. 120 women with antenatal steroid application were included into our analysis. Descriptive statistics were performed to analyze factors influencing the timing of antenatal steroids and to evaluate additional medical interventions which women with imminent preterm birth experience.

Results
Of the 120 women included into our study, 35.8% gave birth before 34/0 weeks and 64.2% before 37/0 weeks of gestation. Only 25/120 women (20.8%) delivered within the optimal time window of 1–7 days after antenatal steroid application. 5/120 women (4.2%) only received one dose of antenatal steroids before birth and 3/120 (2.5%) gave birth within 8 to 14 days after antenatal steroids. Most women gave birth more than 14 days after steroid application (72.5%, 87/120). Women with preeclampsia (60%), PPROM (31%), and FGR (30%) had the highest rates of delivery within the optimal time window. Women of all timing groups received additional interventions and medications like antibiotics, tocolytics, or anticoagulation.

Conclusion
Our observational data indicate that most pregnant women do not give birth within 7 days after the administration of antenatal steroids. The timing was best for preterm birth due to preeclampsia, PPROM, and FGR. Especially for women with symptoms of preterm labor and bleeding placenta previa, antenatal steroids should be indicated more restrictively to improve neonatal outcome and reduce untimely and unnecessary interventions.
Role of the cerebro-placental-uterine ratio in predicting adverse perinatal outcome in low-risk pregnancies at term
Authors: Graupner Oliver , Meister Markus , Lecker Linda , Karim-Payab Sepideh , Franz Cordula , Carow Juliane , Enzensberger Christian 
Published: August 2022

Abstract
Purpose
The cerebroplacental ratio (CPR) is associated with adverse perinatal outcome (APO) in low-risk pregnancies near term. A Doppler parameter, which also includes information from the uterine vessels could potentially improve detection of subclinical placental dysfunction. The aim of this study is to investigate the performance of cerebro-placental-uterine ratio (CPUR) related to APO prediction in low-risk term pregnancies in > 40 + 0 weeks.

Methods
This is a retrospective cohort study. All low-risk pregnancies in which feto-maternal Doppler was examined from 40 + 0 weeks and an appropriate for gestational age fetus was present were included. ROC (receiver operating characteristic curves) analyses were performed to assess the predictive value of CPUR. The presence of at least one of the following outcome parameters was defined as composite APO (CAPO): operative delivery (OD) due to intrapartum fetal compromise (IFC), admission to the neonatal intensive care unit, umbilical cord arterial pH ≤ 7.15, 5 min APGAR ≤ 7.

Results
A total of n = 114 cases were included. Mean gestational age at examination and delivery were 40 + 3 weeks and 40 + 6 weeks, respectively. Overall, CAPO occurred in 38 of 114 cases (33.3%). ROC analyses showed a significant association of CPUR (AUC = 0.67, p = 0.004) and CPR (AUC = 0.68, p = 0.002) with CAPO. Additionally, CPUR (AUC = 0.64, p = 0.040) showed a predictive value for OD due to IFC.

Conclusion
The CPUR in > 40 + 0 weeks showed a predictive value for CAPO and OD due to IFC in low-risk pregnancies. However, the extent to which CPUR can be used to optimize delivery management warrants further investigations in prospective interventional studies.