bluuebunny/crossref_metadata_2025_split huggingface dataset:
An evidence review and nutritional conceptual framework for pre-eclampsia prevention
Authors: Kinshella Mai-Lei Woo , Pickerill Kelly , Bone Jeffrey N. , Prasad Sarina , Campbell Olivia , Vidler Marianne , Craik Rachel , Volvert Marie-Laure , Mistry Hiten D. , Tsigas Eleni , Magee Laura A. , von Dadelszen Peter , Moore Sophie E. , Elango Rajavel ,   the PRECISE Conceptual Framework Working Group
Published: December 2022

AbstractPre-eclampsia is a serious complication of pregnancy, and maternal nutritional factors may play protective roles or exacerbate risk. The tendency to focus on single nutrients as a risk factor obscures the complexity of possible interactions, which may be important given the complex nature of pre-eclampsia. An evidence review was conducted to compile definite, probable, possible and indirect nutritional determinants of pre-eclampsia to map a nutritional conceptual framework for pre-eclampsia prevention. Determinants of pre-eclampsia were first compiled through an initial consultation with experts. Second, an expanded literature review was conducted to confirm associations, elicit additional indicators and evaluate evidence. The strength of association was evaluated as definite relative risk (RR) < 0·40 or ≥3·00, probable RR 0·40–0·69 or 1·50–2·99, possible RR 0·70–0·89 or 1·10–1·49 or not discernible RR 0·90–1·09. The quality of evidence was evaluated using Grading of Recommendations, Assessment, Development and Evaluation. Twenty-five nutritional factors were reported in two umbrella reviews and twenty-two meta-analyses. Of these, fourteen were significantly associated with pre-eclampsia incidence. Higher serum Fe emerged as a definite nutritional risk factors for pre-eclampsia incidence across populations, while low serum Zn was a risk factor in Asia and Africa. Maternal vitamin D deficiency was a probable risk factor and Ca and/or vitamin D supplementation were probable protective nutritional factors. Healthy maternal dietary patterns were possibly associated with lower risk of developing pre-eclampsia. Potential indirect pathways of maternal nutritional factors and pre-eclampsia may exist through obesity, maternal anaemia and gestational diabetes mellitus. Research gaps remain on the influence of household capacities and socio-cultural, economic and political contexts, as well as interactions with medical conditions.
On conjugacy of subalgebras in graph C*-algebras. II
Authors: Hayashi Tomohiro , Hong Jeong Hee , Szymański Wojciech 
Published: December 2022

AbstractWe apply a method inspired by Popa's intertwining-by-bimodules technique to investigate inner conjugacy of MASAs in graph $C^*$-algebras. First, we give a new proof of non-inner conjugacy of the diagonal MASA ${\mathcal {D}}_E$ to its non-trivial image under a quasi-free automorphism, where $E$ is a finite transitive graph. Changing graphs representing the algebras, this result applies to some non quasi-free automorphisms as well. Then, we exhibit a large class of MASAs in the Cuntz algebra ${\mathcal {O}}_n$ that are not inner conjugate to the diagonal ${\mathcal {D}}_n$.
The Right to Health in Nigeria and Its Impact on Citizens’ Access to Medical Care
Authors: Lugard Sunday Bontur 
Published: December 2022

AbstractThe socio-economic and productive strength of every nation is determined by the health (the physical, mental and psychological wellbeing) of its people. To guarantee this, the constitutions of some countries, including Nigeria, provide for the right to health, and have framed institutional and policy systems to operationalize and realize this goal, as one of the major objectives of governments. However, despite this great intention on paper, the realization of good healthcare for most of the citizens of this country is still a mirage, despite legal and policy interventions in the form of human rights. The question is, can a rights-based approach to healthcare facilitate or guarantee the realization of this normative claim through access to medical care? This article contends that mere legal and policy frameworks that guarantee the right to health do not automatically engender access to good medical care, as there are hurdles to cross beyond the “limit of available resources”.
A region in dispute: Racialized anticommunism and Manila’s role in the origins of Konfrontasi, 1961–63
Authors: Scalice Joseph 
Published: December 2022

AbstractPrior scholarship has treated the Philippines as an outside party to the conflict over the formation of Malaysia, known as Konfrontasi, which has been dealt with as a dispute between Malaysia and Indonesia. This article demonstrates the centrality of the Macapagal administration to the origins of Konfrontasi. Treating Manila as a core actor gives new insight into Konfrontasi, which can be best understood as a regional conflict over the racial and social shape of island Southeast Asia in the final stages of decolonization. Racialized anticommunism, expressed through the forcible redivision of the region to ensure social stability, emerges as the preoccupation of all the state actors promoting and opposing the formation of Malaysia. At the same time, an examination of developments in the Philippines and the actions of the Partido Komunista ng Pilipinas (PKP) gives new insight into the critical function of the Partai Komunis Indonesia (PKI) in this affair.
Effects of seed size and toucan regurgitation on the germination of the tropical tree Eugenia uniflora
Authors: Jones Landon R. , Hunts Chelsey A. , Dolan Lacy A. , Murphy Natasha K. , Ripa Gabrielle N. , Schultz Emma A. , Shastry Varsha S. , Sklarczyk Craig A. , Thornton Bradly S. , Boudreau Melanie R. 
Published: December 2022

Abstract
Understanding the quality of seed dispersal effectiveness of frugivorous species can elucidate how endozoochory structures tropical forests. Large seeds, containing more resources for growth, and gut passage by frugivores, which remove seed pulp, both typically enhance the speed and probability of germination of tropical seeds. However, the interaction of seed size and gut passage has not been well studied. We assessed the role of two species of toucans (Ramphastos spp.) in seed germination of the tropical tree Eugenia uniflora, which produces seeds that vary considerably in size (3.7–14.3 mm), using 151 control and 137 regurgitated seeds in germination trials. We found that toucan regurgitation did not increase germination success, although 93.4% germinated compared to 76.8% of control seeds; however, larger seeds germinated more often at faster rates. Although only marginally significant, germination rates were 3.6× faster when seeds were both large and regurgitated by toucans, demonstrating that toucan regurgitation can disproportionally benefit larger E. uniflora seeds. As tropical forests are increasingly disturbed and fragmented by human activities, the ability of toucans to continue providing seed dispersal services to degraded habitats may be vital to the persistence of many tropical plants that contain larger seeds and depend on larger dispersers.
Hail-caused greenfall leaves, litterfall, nutrients, and leaf decomposition in tropical cloud forest and a restoration planting
Authors: Williams-Linera Guadalupe , Tolome Javier , Alvarez-Aquino Claudia 
Published: December 2022

Abstract
Greenfall leaves caused by hailstorms may represent a resource pulse of nutrients. We determined the contribution of greenfall versus senescent leaves to total litterfall production, carbon, nitrogen and phosphorus input to the system, and leaf decomposition rate. Litterfall was collected monthly for three years in two cloud forests (F1, F2) and a restoration planting area (R) in Veracruz, Mexico. Two fortuitous hailstorms occurred in the second year. Leaf decomposition rate was determined in all three sites but did not differ across them. Total annual litterfall, excluding greenfall, was 10.0, 10.1, and 7.7 Mg ha−1 y−1 for F1, F2, and R, respectively. Senescent leaves represented 65% of the litterfall, while greenfall leaves increased the annual leaf biomass component of the litterfall by 12%. Concentrations of carbon, nitrogen, and phosphorus were 2.3, 5.7, and 18.1% higher, respectively, in greenfall than in senescent leaves. Greenfall increased the annual input of C, N, and P by 12, 13, and 14%, respectively. Despite their short duration (approximately 70 minutes), the hailstorm events generated a substantial contribution of greenfall leaves and a source of extra C, N, and P, since these leaves decompose and are incorporated into the cloud forest system.
The survival of epidemic and sporadic MRSA on human skin mimics is determined by both host and bacterial factors
Authors: Baede Valérie O. , Voet Michella M. , van der Reijden Tanny J. K. , van Wengen Annelies , Horst-Kreft Deborah E. , Lemmens-den Toom Nicole A. , Tavakol Mehri , Vos Margreet C. , Nibbering Peter H. , van Wamel Willem J. B. 
Published: December 2022

AbstractBacterial survival on, and interactions with, human skin may explain the epidemiological success of MRSA strains. We evaluated the bacterial counts for 27 epidemic and 31 sporadic MRSA strains on 3D epidermal models based on N/TERT cells (NEMs) after 1, 2 and 8 days. In addition, the expression of antimicrobial peptides (hBD-2, RNase 7), inflammatory cytokines (IL-1β, IL-6) and chemokine IL-8 by NEMs was assessed using immunoassays and the expression of 43S. aureusvirulence factors was determined by a multiplex competitive Luminex assay. To explore donor variation, bacterial counts for five epidemic and seven sporadic MRSA strains were determined on 3D primary keratinocyte models (LEMs) from three human donors. Bacterial survival was comparable on NEMs between the two groups, but on LEMs, sporadic strains showed significantly lower survival numbers compared to epidemic strains. Both groups triggered the expression of immune factors. Upon interaction with NEMs, only the epidemic MRSA strains expressed pore-forming toxins, including alpha-hemolysin (Hla), gamma-hemolysin (HlgB), Panton-Valentine leucocidin (LukS) and LukED. Together, these data indicate that the outcome of the interaction between MRSA and human skin mimics, depends on the unique combination of bacterial strain and host factors.
Fluctuations of subgraph counts in graphon based random graphs
Authors: Bhattacharya Bhaswar B. , Chatterjee Anirban , Janson Svante 
Published: December 2022

AbstractGiven a graphon
$W$
and a finite simple graph
$H$
, with vertex set
$V(H)$
, denote by
$X_n(H, W)$
the number of copies of
$H$
in a
$W$
-random graph on
$n$
vertices. The asymptotic distribution of
$X_n(H, W)$
was recently obtained by Hladký, Pelekis, and Šileikis [17] in the case where
$H$
is a clique. In this paper, we extend this result to any fixed graph
$H$
. Towards this we introduce a notion of
$H$
-regularity of graphons and show that if the graphon
$W$
is not
$H$
-regular, then
$X_n(H, W)$
has Gaussian fluctuations with scaling
$n^{|V(H)|-\frac{1}{2}}$
. On the other hand, if
$W$
is
$H$
-regular, then the fluctuations are of order
$n^{|V(H)|-1}$
and the limiting distribution of
$X_n(H, W)$
can have both Gaussian and non-Gaussian components, where the non-Gaussian component is a (possibly) infinite weighted sum of centred chi-squared random variables with the weights determined by the spectral properties of a graphon derived from
$W$
. Our proofs use the asymptotic theory of generalised
$U$
-statistics developed by Janson and Nowicki [22]. We also investigate the structure of
$H$
-regular graphons for which either the Gaussian or the non-Gaussian component of the limiting distribution (but not both) is degenerate. Interestingly, there are also
$H$
-regular graphons
$W$
for which both the Gaussian or the non-Gaussian components are degenerate, that is,
$X_n(H, W)$
has a degenerate limit even under the scaling
$n^{|V(H)|-1}$
. We give an example of this degeneracy with
$H=K_{1, 3}$
(the 3-star) and also establish non-degeneracy in a few examples. This naturally leads to interesting open questions on higher order degeneracies.
Resection of an immature intrapericardial teratoma from a premature neonate presenting as hydrops foetalis
Authors: Mazalan S. Laura , Yubbu Putri , Velayudham V. Ramesh 
Published: December 2022

AbstractIntrapericardial teratoma is a germ-cell tumor that typically arises from the base of the heart. This rare cardiac tumour is the second most common tumor diagnosed in fetuses and newborn. Although benign, it can be massive in size causing direct compression on the heart and associated with significant pericardial effusion resulting life-threatening complications such as cardiac tamponade, heart failure, foetal hydrops, and sudden death. Early antenatal diagnosis and surgical intervention improve the survival. We present a case of immature intrapericardial teratoma diagnosed at 25 weeks of gestation but required multiple foetal pericardiocentesis and premature delivery due to massive pericardial effusion. The importance of multidisciplinary team approach to ensure successful management was highlighted in this case report.
Introduction of specialized heart failure nurses in primary care and its impact on readmissions
Authors: Kristiansson Robert S. , Ssegonja Richard , Ropponen Alina , Olsson Anna , Sampaio Filipa 
Published: December 2022

Abstract

Background:
Heart failure (HF) has a 2% prevalence in the population and is a major cause of morbidity and mortality. Multiple efforts have been made worldwide to improve quality of care and decrease unplanned readmissions for HF patients, one of which has been the introduction of specialist HF nurses (HFN) in primary health care. The present evidence on the benefits of HFN is contradicting. This study aims to evaluate the impact of a quality improvement intervention, availability of a HFN in Swedish primary care, on hospital readmissions.

Methods:
All patients over the age of 65 with a HF diagnosis and with complete information on availability of a HFN were included in this retrospective register-based study. Using propensity score matching (PSM) techniques, two comparable groups of 128 patients each were created according to the exposure status, availability or no availability of a HFN. The rate of readmission was compared between the groups.

Results:
Using PSM, 256 patients were matched, 128 in the HFN group and 128 in the no-HFN group. A total of 50% and 46.09% of patients in the HFN and no-HFN groups were readmitted, respectively. Mean number of readmissions per patient was 1.19 (SD 0.61) in the HFN group and 1.10 (SD 0.44) in the no-HFN group. Patients in the HFN had 17.6% higher odds of being readmitted during the study period, OR: 1.176 (CI: 0.716–1.932), and 3.8% lower odds of being readmitted within 30 days, OR: 0.962 (CI: 0.528–1.750).

Conclusions:
Availability of a HFN in primary care was not significantly associated with reduced readmissions for the patients included in this study. Further investigations are warranted looking at the impacts of availability and access to a HFN in primary care on readmissions and other patient outcomes.
Experience of application of the meaning-centered psychotherapy to Japanese bereaved family of patients with cancer – A mixed-method study
Authors: Koda Rumiko , Fujisawa Daisuke , Kawaguchi Mayu , Kasai Hitoshi 
Published: December 2022

AbstractObjectivesThis study aimed to adapt the meaning-centered psychotherapy (MCP) to treat post-bereavement grief in Japanese bereaved families who lost their loved ones to cancer and to examine the feasibility of the intervention using both quantitative and qualitative methods.MethodsA modified version of MCP was developed with cultural consideration. Bereaved individuals aged ≥18 years who had lost their family members to cancer at least 6 months before and had severe or persistent grief with a score of ≥26 on the Inventory of Complicated Grief (ICG-19) were included in the study. The participants received the modified version of MCP, which was provided in a 5-session monthly format. The levels of grief (ICG-19), depression (Center for Epidemiologic Studies Depression Scale [CES-D]), general health (General Health Questionnaire-12), and post-traumatic growth (Post-traumatic Growth Inventory -Short Form) were compared before and after the intervention.ResultsFive bereaved individuals were enrolled, and all the participants completed the program. The mean scores of the ICG-19. The participants’ sense of regret, guilt, and being separated from the deceased person gradually shifted to the reappraisal of the experience, leading to a broadened view of the relationship with the deceased, and rediscovery of the core values, identity, and roles of the participants through the process of rediscovery of the meaning of life.Significance of resultsA modified version of the MCP was well accepted by Japanese bereaved families. The intervention appears to promote the rediscovery of the meaning of life and appears to have the potential to alleviate the bereaved individuals’ depression and grief-related symptoms and to facilitate their post-traumatic growth.
Deep Learning Based Cloud Cover Parameterization for ICON
Authors: Grundner Arthur , Beucler Tom , Gentine Pierre , Iglesias‐Suarez Fernando , Giorgetta Marco A. , Eyring Veronika 
Published: December 2022

AbstractA promising approach to improve cloud parameterizations within climate models and thus climate projections is to use deep learning in combination with training data from storm‐resolving model (SRM) simulations. The ICOsahedral Non‐hydrostatic (ICON) modeling framework permits simulations ranging from numerical weather prediction to climate projections, making it an ideal target to develop neural network (NN) based parameterizations for sub‐grid scale processes. Within the ICON framework, we train NN based cloud cover parameterizations with coarse‐grained data based on realistic regional and global ICON SRM simulations. We set up three different types of NNs that differ in the degree of vertical locality they assume for diagnosing cloud cover from coarse‐grained atmospheric state variables. The NNs accurately estimate sub‐grid scale cloud cover from coarse‐grained data that has similar geographical characteristics as their training data. Additionally, globally trained NNs can reproduce sub‐grid scale cloud cover of the regional SRM simulation. Using the game‐theory based interpretability library SHapley Additive exPlanations, we identify an overemphasis on specific humidity and cloud ice as the reason why our column‐based NN cannot perfectly generalize from the global to the regional coarse‐grained SRM data. The interpretability tool also helps visualize similarities and differences in feature importance between regionally and globally trained column‐based NNs, and reveals a local relationship between their cloud cover predictions and the thermodynamic environment. Our results show the potential of deep learning to derive accurate yet interpretable cloud cover parameterizations from global SRMs, and suggest that neighborhood‐based models may be a good compromise between accuracy and generalizability.
Relativistic Microburst Scale Size Induced by a Single Point‐Source Chorus Element
Authors: Kang Ning , Bortnik Jacob , Zhang Xiaojia , Claudepierre Seth , Shi Xiaofei 
Published: December 2022

AbstractRelativistic microbursts are impulsive, sub‐second precipitation bursts of relativistic electrons. They are one of the main loss mechanisms of outer radiation belt electrons, and are driven by chorus waves. The scale size of relativistic microbursts is still not fully understood. In this work a global modeling of the microburst spatial distribution is conducted to study the scale size of relativistic microburst induced by chorus waves. A primary precipitation burst is induced near the source region by quasi‐parallel waves, and a secondary precipitation (SP) is induced on higher L‐shells by further‐propagating, oblique waves. The SP has a significant scale size even with a point‐source assumption because of wave spreading due to propagation effect. The secondary relativistic microburst scale size is ∼40(20) km on the counter (co)‐streaming side, consistent with previous observations. Our modeling results indicate chorus wave propagation effects are one of the primary factors controlling the relativistic microburst scale size.
Effects of Stratospheric Gravity Waves on Convection in the Troposphere During Typhoon Lekima 2019
Authors: Wang Xu , Zhang Lifeng , Wang Yuan , Guan Jiping , Zhang Yun 
Published: December 2022

AbstractThe influence of stratospheric gravity waves (SGWs) on the intensity of convection (CI) in the area of heavy precipitation around Typhoon Lekima (2019) is studied. Using theory and simulations, the energy and phase of the SGWs are shown to propagate upward and downward. The SGWs can propagate downward into the areas of convective instability in the upper troposphere in 35–85 min. Downward‐propagating SGWs can promote the release of convective instability energy, so the CI is enhanced. The relationship between SGWs and CI after 85 min is studied using a two‐layer model hypothesis for both a linear regression model and a Long Short‐Term Memory neural network model (nonlinear). The relationship is shown to be primarily linear (nonlinear) when the SGWs are weak (intensive). Therefore, the SGWs may be used as a proxy for the CI.
A Comparative Study on Heterogeneity of Clay Rocks Using Pore‐Scale Diffusion Simulations and Experiments
Authors: Yuan Tao , Yang Yuankai , Ait‐Mouheb Naila , Deissmann Guido , Fischer Cornelius , Stumpf Thorsten , Bosbach Dirk 
Published: December 2022

AbstractAccurate modeling and simulation of radionuclide migration in clay rocks such as the Opalinus Clay (OPA) play a key role in the safety assessment of deep geological repositories for nuclear wastes. At the continuum scale, the representative elementary volume (REV) is a fundamental constraint to quantify the effective diffusivity, which is a key parameter in reactive transport (RT) models. Therefore, an accurate estimation of the REV is essential for a meaningful continuum‐scale RT simulation in heterogeneous clay rocks. This study presents a comprehensive analysis of the heterogeneities of porosity and effective diffusivity in clay rocks by using the classical sampling theory and pore‐scale simulations. First, in this study, the two‐dimensional representative elementary area is correlated with the REV for porosity via a characteristic length. Next, it is shown that the REV for diffusivity is larger than the REV for porosity. Moreover, these two REVs can be correlated using Archie's law. In such a way, the REV for diffusivity can be determined by the developed correlations through analyzing two‐dimensional microstructures, thus significantly reducing the computational cost. Finally, the applicability of our approach for clay rocks is validated by experimental data on the diffusion of tritiated water in the heterogeneous sandy facies of OPA. From both the experimental data and the modeling prediction, the REV for diffusivity in the sandy facies of OPA is in the order of cubic centimeters. This study provides critical insights into the diffusion in heterogeneous clay rocks toward an enhanced predictability of radionuclide migration.