bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is Anxiety Affecting the Adoption of ChatGPT in University Teaching? A Gender Perspective
Authors: Bolívar-Cruz Alicia , Verano-Tacoronte Domingo 
Published: February 2025

Abstract
The emergence of ChatGPT and other AI-based tools has revolutionized the professional and educational world. This paper aims to analyze the factors that may lead university teachers to consider adopting ChatGPT in their work. This study examines how some relevant Unified Theory of Acceptance and Use of Technology (UTAUT) model variables (effort expectancy, facilitating conditions, and performance expectancy), technology-related anxiety and gender influence teachers’ intentions to use ChatGPT. A questionnaire was developed and sent to professors at Spanish public universities, resulting in a sample of 249 valid responses. The results indicate that performance expectancy, facilitating conditions, anxiety related to student learning and gender are the main determinants of the intention to use ChatGPT by teachers. After conducting an exploratory analysis segmented by gender, it was found that men and women analyze the possibility of adopting ChatGPT through different variables. For male teachers, performance expectancy and facilitating conditions are the variables that affect the intention to use ChatGPT. In contrast, female teachers’ intention is influenced by anxiety related to student learning and anxiety related to technology use, in addition to performance expectancy and facilitating conditions. Therefore, these results suggest that it is crucial to consider individual perceptions, gender as well as contextual factors when promoting the adoption of tools such as ChatGPT among university teachers. Educational institutions should provide teachers with the skills needed to create, adapt and use information and communication technologies, especially those based on generative AI. This training should adopt new strategies that take gender differences into account.
Papillary craniopharyngioma management in the era of BRAF and MEK inhibition
Authors: Damante Mark , Cua Santino , Kreatsoulas Daniel , Giglio Pierre , Ghalib Luma , Biswas Chandrima , Wu Kyle C. , Prevedello Daniel M. 
Published: February 2025

Abstract

Purpose
Papillary craniopharyngioma is a rare entity, demonstrating BRAF-V600E mutations in approximately 95% of patients. Recently, a phase 2 trial of patients treated with surgery and BRAF/MEKi demonstrated 91% reduction in residual tumor volume. This study allowed for additional treatments at the discretion of the treatment team without reporting subsequent rates of endocrinopathy or visual decline. We aimed to evaluate the possibility of employing BRAF/MEKi without the need for adjuvant radiotherapy therapies.

Methods
A retrospective report of two patients treated with resection and BRAF/MEKi without additional treatment were analyzed. Patient demographics, treatment characteristics, pre- and post-treatment radiographic volumes, adverse events, and endocrinologic and visual outcomes, were recorded and analyzed.

Results
Two patients underwent subtotal resection followed by BRAF/MEKi without adjuvant treatment. Mean length of BRAF therapy was 21.4 months and MEKi therapy was 12.94 months. Mean preoperative nodule volume was 0.33 cm [3] and 2.29 cm [3] and cystic volume was 5.04 cm [3] and 6.18 cm [3] in case 1 and case 2, respectively. Neither patient received radiation. Grade 3 cardiotoxicity developed in case 1 after 6.5 months, with function recovering completely following discontinuation of MEKi. BRAF therapy was discontinued electively after 23.5 months. The second patient remains on dual inhibition therapy without toxicity. For these cases, post-treatment nodule volumes are 0.07 cm [3] (98.4% reduction) and 0.04 cm [3] (99.2% reduction), respectively, and cystic volume 0.0 cm [3] in both patients. Progression free survival is 100% with a mean follow up of 36-months.

Conclusions
Utilizing surgery and BRAF/MEKi without adjuvant radiation, we demonstrate excellent disease control with reversible toxicity. Avoiding additional treatments may spare vital functions and unnecessary procedures.
Wealth and Income Stratification by Social Class in Five European Countries
Authors: Gil-Hernández Carlos J. , Salas-Rojo Pedro , Vidal Guillem , Villani Davide 
Published: February 2025

Abstract
Wealth is a central determinant of life chances and intergenerational status persistence in modern societies. Despite increasing attention, sociologists traditionally overlooked its role in class-based economic disparities, while most economists focused on the elites’ accumulation. This article combines sociological and economic perspectives to test whether big occupational classes, the most standardised and operationalisable approach, depict the wealth distribution. Drawing from the Luxembourg Wealth Study (2002–2018) in five European countries, we explore (1) how wealth is distributed and stratified by big occupational classes over time and cross-nationally and (2) to what extent classes account for aggregate wealth inequality trends compared with income. Unlike bold claims on class 'death' or 'decomposition', inequality of outcomes in wealth accumulation is firmly rooted across big occupational classes in contemporary capitalism, potentially harming social mobility in future generations. Still, occupational classes better capture between-group income inequality and stratification than wealth, emphasising the importance of economic resources beyond labour market attachment. Against the backdrop of previous research and our findings, we discuss the role of wealth in contemporary class analysis.
Inference on diffusion processes related to a general growth model
Authors: Albano Giuseppina , Barrera Antonio , Giorno Virginia , Torres-Ruiz Francisco 
Published: February 2025

Abstract
This paper considers two stochastic diffusion processes associated with a general growth curve that includes a wide family of growth phenomena. The resulting processes are lognormal and Gaussian, and for them inference is addressed by means of the maximum likelihood method. The complexity of the resulting system of equations requires the use of metaheuristic techniques. The limitation of the parameter space, typically required by all metaheuristic techniques, is also provided by means of a suitable strategy. Several simulation studies are performed to evaluate to goodness of the proposed methodology, and an application to real data is described.
Microplastic uptake by birds: from observation to development of a novel seed coating to prevent bird predation of corn seeds
Authors: Accinelli Cesare , Bruno Veronica , Abbas Hamed K. , Morena Chiara , Khambhati Vivek H. , Shier Wayne T. 
Published: February 2025

Abstract
The occurrence of microplastics in soil is an emerging issue that not only impacts soil ecology but also has the potential to affect terrestrial birds foraging in agricultural fields. Foraging birds may unintentionally take up soil-borne microplastics along with soil adhering to crop residues and seeds of cultivated species. Microplastic uptake by foraging terrestrial bird species, including Pica pica (magpie), Corvus cornix (hooded crow), and Columba palumbus (common wood pigeon), studied using camera traps, showed that the risk of MP uptake by these birds microplastics from compostable plastic bags was elevated by 27 and 78% when the microplastic particles were associated with corn seed grits or corn seeds, respectively. When these film fragments were coated with a slurry containing tannic acid, saponin, and juglone, microplastic uptake was significantly reduced. Similarly, coating corn seeds with this repellent slurry reduced seed predation by birds up to 86%, and completely wrapping corn seeds with a repellent plastic film resulted in no observed seed predation by birds. The same results were obtained when the wrapping film was replaced by a seed coating containing hairy cotton fibers which may have triggered a feather fear or repulsion response in the birds. This study demonstrated that covering corn seeds with natural repellents or hairy filaments provided complete protection from bird predation.
Galanthus subalpinus (Amaryllidaceae): a new species of snowdrop from the Western Balkans
Authors: Davis Aaron P. , McEnery Ian , Csiba Laszlo , Márquez-Corro José Ignacio , Leitch Ilia J. 
Published: February 2025

Summary

Galanthus subalpinus (Amaryllidaceae), a new snowdrop species endemic to the Western Balkans (North Macedonia and Kosovo) is described and illustrated. Morphological differences between the new species and the similar Galanthus species, G. nivalis and G. graecus, are reported and discussed, in combination with DNA sequence data from plastid (trnL-trnF, matK) and nuclear (ribosomal ITS) markers and genome size. Line drawings, photographs of habitat and morphology, a distribution map and a preliminary conservation assessment are provided. The genome size (1C-value) of G. bursanus, G. samothracicus and G. × valentinei nothosubsp. subplicatus are reported for the first time.
Stress field and safe drilling mud weights in the Shizigou salt system of Yingxiongling, Qaidam Basin, China
Authors: Liu Jihan , Luo Gang , Wang Mingwen 
Published: February 2025

Abstract
In this study, we calculate stress perturbations around the salt diapir in the Shizigou salt system of Qaidam Basin, China, by using a three-dimensional finite element model. Our goal is to identify safe mud weight windows around the salt in this complex region. We establish the salt-system geomechanical model by integrating seismic and logging data and inputting rock material properties and regional background stress field. The results show that the presence of the gypsum salt layer and structural decoupling lead to variations in principal stress directions (
$$\:{\sigma\:}_{2}$$
and
$$\:{\sigma\:}_{3}$$
) above and below the salt. Stress perturbations around salt rocks, or mechanical compaction effects from the salt rocks, are closely related to their geometric shapes and regional background stress field. Mismatches between the hydrostatic drilling fluid (mud) pressure and formation pressure can induce the drilling accidents. Therefore, based on model stress results, formation pore fluid pressure, and the Drucker–Prager plastic criterion, we conduct a drilling risk assessment. We find that drilling through large-scale concave salt structures is relatively safe with wide safe drilling windows, but at other locations, safe drilling windows are narrow. The stricter condition (wellbore collapse width less than 120°) reduces the range of the safe drilling window at salt convexities by 60%. Our study, through the establishment of a geomechanical model, provides practical insights for reducing drilling risks and designing drilling mud weights and routes.
β-Hydroxybutyrate mitigates the detrimental effects of high glucose in human retinal pigment epithelial ARPE-19 cells
Authors: Argentino Francesca , Mallardo Marta , Costagliola Ciro , Daniele Aurora , Nigro Ersilia 
Published: February 2025

Abstract
High glucose leads to cellular damage and dysfunction in the retina. Dietary interventions, including the use of ketogenic diets, have been explored for their potential to reduce the adverse effects of hyperglycemia. β-Hydroxybutyrate (BHB), a ketone body, has immune and anti-inflammatory properties. This study aims to investigate whether BHB ameliorates the harmful effects induced by high glucose in ARPE-19 cells, a model of retinal pigment epithelium. We investigated the effects induced by high glucose and/or BHB on viability, migration, colony-forming ability, cell cycle progression and cytokine production. Our data indicate that high glucose significantly reduces the viability of ARPE-19 cells with no significant changes in apoptosis or autophagy, while inducing cell cytostasis. On the other hand, BHB exerts a protective effect on ARPE-19 cells under hyperglycemic conditions improving cell viability and alleviating glucose-induced cell cycle arrest. Additionally, BHB treatment affects the expression of IL-8 and IL-17α, as well as of MCP-1, modulating the inflammatory response, cell migration and wound healing. In conclusion, this study highlights the potential protective role of BHB against the detrimental effects induced by high glucose on ARPE-19 cells. These findings support the use of ketone bodies in mitigating high glucose-induced cellular damage. Future research will be critical to translate these findings to the clinical practice for metabolic diseases.
Oral nonabsorbable antibiotics for prevention of recurrent cholangitis; a brief report study
Authors: Fortún Jesús , Rodríguez-Gandía Miguel Angel , Pintado Vicente , Martín-Dávila Pilar , García-González Miguel , Graus Javier , Martín-Mateos Rosa , Fuente Javier Sáez de la , Muriel Alfonso , Moreno Santiago 
Published: February 2025

Abstract

Background
Patients with recurrent cholangitis are at risk of developing life-threatening sepsis. Selective decontamination of the digestive tract (SDD) involving oral nonabsorbable antibiotics has been primarily applied to children undergoing Kasai portoenterostomy surgery.

Methods
In this study, SDD containing colistin, tobramycin, and nystatin was administered to eight patients with recurrent cholangitis, and the incidence density before and after SDD administration was analyzed.

Results
The overall incidence density of cholangitis requiring hospital admission was 0.37 per 100 patient days during the SDD period and was significantly lower than observed before SDD administration (1.05 per 100 patient days) [RR: 0.35 (95% CI: 0.21–0.59); p: <0.001, two-sided]. This was not associated with an increased risk of resistance during SDD administration.

Conclusion
In this study SDD reduced by 65% the frequency and severity of recurrent cholangitis. In addition, this procedure is patient-friendly and microbiologically safe.
Institutionelle Designfehler im Kontext des Gesundheitswesens: Zur epistemischen Handlungsfähigkeit von Personen mit Behinderung oder chronischer Erkrankung
Authors: Hänel Hilkje C. 
Published: February 2025

Zusammenfassung
Ausgehend von standpunkttheoretischen Überlegungen soll gezeigt werden, dass behinderte und chronisch kranke Personen notwendige Erkenntnisse über Gestaltungsfehler von Institutionen des Gesundheitswesen haben können; einerseits, indem sie aufgrund ihrer Abhängigkeit von diesen Institutionen Probleme wahrnehmen, die von anderen übersehen werden und, andererseits, weil sie bereits Handlungsstrategien der Navigation dieser Institutionen entwickelt haben, die zur Fehlerbehebung herangezogen werden können. Dabei liegt ein Fokus auf sogenannten dominanten Intelligibilitätsrahmen, die dazu führen, dass Institutionen des Gesundheitssystems schon in ihrer Gestaltung problematische Züge annehmen können. Wohingegen sich die bisherige Forschung auf sogenannte interpersonale Probleme innerhalb von Institutionen (zum Beispiel aufgrund von problematischen Vorurteilen oder Unwissen von Akteuer*innen innerhalb der Institutionen) fokussiert, soll hier das folgende Problem beleuchtet werden: Trotz der Tatsache, dass die in Gesundheitsinstitutionen beschäftigten Akteur*innen einen moralischen Anspruch an ihr Handeln anlegen (diese berufsethischen Wertevorstellungen spiegeln sich zumindest teilweise in den Berufsordnungen der jeweiligen Landesärztekammern oder Gelöbnissen wie der Genfer Deklaration des Weltärztebundes und werden populärwissenschaftlich durch Hippokratischen Eid beschrieben), lassen sich gerade auch im Gesundheitswesen problematische epistemische Praktiken auffinden, die – so die These des Artikels – bereits im Design der jeweiligen Institution angelegt sind und nicht in den spezifischen Handlungen der dort Beschäftigten.
Role of strategies used by young people for dealing with emotional distress: a qualitative study in deprived urban neighborhoods in Latin America
Authors: Jaramillo Isabela Osorio , Gomez-Restrepo Carlos , Brusco Luis Ignacio , Diez-Canseco Francisco , Fung Catherine , Ariza-Salazar Karen , Olivar Natividad , Toyama Mauricio , Sureshkumar Diliniya Stanislaus , Uribe-Restrepo José Miguel , Carbonetti Fernando Luis , Vilela-Estrada Ana L. , Priebe Stefan 
Published: February 2025

Abstract

Background
Many young people achieve recovery from mental health problems by using strategies to manage emotional distress and enhance well-being. Given that little is known about the functions of these strategies, especially in Latin American countries, this study aims to describe the usefulness of the resources used by youth from deprived urban neighborhoods in Bogotá (Colombia), Buenos Aires (Argentina), and Lima (Perú) in managing emotional distress.

Methods
112 in-depth interviews about strategies for dealing with emotional distress and their perceived function were conducted with young people from three Latin American cities. The sample included young adults and adolescents in a longitudinal cohort study. A thematic content analysis was carried out.

Results
Participants identify different functions linked to their strategies to cope with emotional distress or increase their well-being. However, "coping with distress," "perceived support," and "distraction" are the three main functions of the strategies used by them in situations of emotional distress. Each of these functions comprises several aspects, some of which overlap between functions, such as motivation, emotional expression, companionship, and regulation.

Conclusion
The variety of functions linked to the strategies used by young people to cope with emotional distress or enhance their well-being could guide the facilitation of a favorable social and interpersonal context through public policies and a community approach that promotes young people's access to strategies to cope with emotional distress.
Analysing complexity in approach control units of metroplex airspaces: insights from air traffic controllers
Authors: Kaçar E. , Aybek Çetek F. , Dönmez K. 
Published: February 2025

Abstract
Safe and efficient flight operations depend on effective air traffic management and the decision-making skills of air traffic control officers (ATCOs). However, managing air traffic in terminal control areas (TMAs), especially in approach control units, is challenging due to the complexity of the airspace. This is particularly evident in metroplex airspaces like the Istanbul TMA, which features multiple civil and military airports, diverse approach systems, and heavy traffic volumes, all contributing to an exceptionally complex operational environment. This study examines how experienced ATCOs perceive airspace complexity, focusing on approach control units within TMAs. Using Istanbul TMA as a case study, the research combines qualitative and quantitative methods to analyse the factors contributing to complexity. In the first phase, the Content Validity Method (CVM) is used to identify and confirm the key factors influencing airspace complexity. In the second phase, the Best-Worst Method (BWM) is applied to measure the importance of these factors. The study involves two groups of ATCOs: 40 in the first group and 20 in the second. The results reveal that ‘conflicts’ are the most critical factor affecting airspace complexity, highlighting the importance of conflict resolution in air traffic control. Other significant factors include rules and procedures, airspace design and traffic density. This study provides clear insights into the challenges of managing TMA, especially in metroplex airspace. Identifying and analysing the key factors offers valuable guidance for improving air traffic management and supporting ATCOs in making better decisions.
Measuring the value of water quality improvements for recreation use on an urban river: a travel cost contingent behavior approach
Authors: Chakrabartty Joy Deep , Parsons George R 
Published: February 2025

Abstract
We estimate the value of water quality improvements for recreational activities on and near the Brandywine Creek in Delaware. We divide water-based recreational activities into two groups: water-contact and non-water-contact. We then consider the behavioral change of the recreationists in each group when faced with water quality improvements posed in a stated preference (contingent behavior) survey. We use five common physical attributes of water quality in the contingent behavior analysis: water clarity, catch rate of fish, safety of eating fish, safety for swimming, and ecological health. The survey was constructed in such a way that each of these attributes of water quality is valued. The per-trip value for water quality improvements ranged from $4 to $63 for contact use and from $4 to $29 for non-contact use depending on which and how many attributes of water quality improve. Even though we measure sizable benefits, rough cost estimates appear to make it difficult for incremental improvements to exceed costs unless attribute improvement is widespread.
Examining the impact of treatment guidelines on outpatient antibiotic prescription trends at a cancer center in Pakistan
Authors: Abbas Salma , Aslam Seemal , Batool Sara , Zafar Mahnoor , Khaliq Sadia , Fatima Momal , Shehzad Iraj , Arslan Muhammad , Attiq Iqra , Shehbaz Muhammad , Khan Anum , Raza Muhammad Ali , Zulfiqar Hamza , Mahmood Ahsan , Sultan Faisal 
Published: February 2025

Abstract

Objective:
To assess the impact of treatment guidelines on the trends of outpatient antibiotic prescription among pediatric and adult patients at a cancer center in Pakistan.

Design:
Retrospective observational study conducted between July 1st 2018 and July 31st 2023.

Methods:
We determined the indication for antibiotics and the frequency of guideline-discordant prescriptions for upper respiratory tract infection (URTI), lower respiratory tract infection (LRTI), urinary tract infection (UTI), and diarrhea. The χ2 test was used to assess the impact of treatment guidelines on antibiotics prescribed for these indications.

Results:
The top indications for antibiotic prescription were skin and skin structure infection (SSSI) (n = 5159; 21.5%), URTI (n = 2760; 11.5%) and UTI (n = 2686; 11.2%). Amoxicillin-clavulanate (n = 7964; 33.3%), was the most frequently prescribed antibiotic. A large proportion of antibiotic prescriptions for URTI, diarrhea, UTI, and LRTI were either inappropriate (n = 6695; 86.5%) or unnecessary (n = 5534; 71.5%). Results revealed a statistically significant decline in the proportion of inappropriate antibiotics for UTI (91.3% vs 84.0%; P ≤ .001) and diarrhea (92.6% vs 87.0%; P = .031) and unnecessary antibiotics for diarrhea (90.2% vs 83.2%; P = .016) with the introduction of treatment guidelines. We noted a higher proportion of unnecessary prescriptions for LRTI (41.7% vs 31.7%; P = .003) and inappropriate antibiotics for UTI (95.1% vs 87.4%; P = .011) for pediatric patients.

Conclusion:
Misuse of outpatient antibiotics is common. Diarrhea, URTI, UTI, and LRTI are high-priority conditions for outpatient oncology-focused prescriber education and stewardship interventions.