bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of erector spinae versus transversus abdominis blocks in ovarian surgery: A randomized, comparative study
Authors: Abdullah Sherif , Elshalakany Nirvana , Farrag Yousr , Abed Sayed 
Published: March 2022

Introduction: Inadequate pain control after major surgery can lead to significant complications. Ultrasound (US) guided plane blocks account for significant progress in regional anesthesia.
Objectives: This study explored the analgesic superiority of ultrasound-guided erector spinae (ESPB) and transversus abdominis (TAPB) plane blocks in patients undergoing major ovarian cancer surgery under general anesthesia. There have been no previous studies comparing their efficacy under these circumstances.
Methods: This double-blind randomized comparative study included 60 patients undergoing major ovarian cancer surgery under general anesthesia. The ESPB group (n=30), received preoperative ultrasound-guided ESPB and the TAPB group (n=30), received preoperative low TAPB. Opioid consumption, HR, MAP, visual analogue scale (VAS) and adverse events were documented over 24 hours after surgery.
Results: There was a highly significant difference in tramadol consumption between the two groups, with (95% CI: 16.23 to 50.43) and (95% CI: 59.23 to 95.43) for ESPB and TAPB groups, respectively. A significant difference (P < 0.01) was shown in intraoperative fentanyl consumption with (95% CI: 113 to 135.6) and (95% CI: 141.8 to 167.6) for ESPB and TAPB groups, respectively. A highly significant longer time to first analgesic request was recorded in the ESPB group (95% CI: 5.5 -15.3) (P < 0.001). VAS had a median of 2 (1-3) and 4 (2-6) for ESPB and TAPB groups, respectively, with F(1)=18.15, P=0.001 between groups. Postoperative HR and MAP in the TAPB group were significantly higher with more incidence of PONV.
Conclusions: ESPB provided a more reliable analgesia versus TAPB in patients undergoing ovarian cancer surgery.
Frequency of carpal tunnel syndrome and hand dysfunction in prediabetes: A cross-sectional, controlled study
Authors: Erol Kemal , Serkan Topaloğlu Ulaş , Fatih Göl Mehmet 
Published: March 2022

Objectives: This study aims to evaluate the frequency of carpal tunnel syndrome (CTS), to investigate the impairment of hand functions in patients with prediabetes (PD), and to compare laboratory findings of PD patients with and without CTS.
Patients and methods: Between June 2018 and January 2019, a total of 115 patients (29 males, 86 females; mean age: 51.4±11.8 years; range, 24 to 78 years) who were recently diagnosed with PD and a total of 54 healthy participants (17 males, 37 females; mean age: 48.4±13.2 years; range, 21 to 78 years) as the control group were included. Demographic and clinical data of the patients including oral glucose tolerance test (OGTT) and glycated hemoglobin (HbA1c) were recorded, and both groups were examined for the presence of CTS. Clinically suspected CTS was confirmed by electrodiagnostic studies. The hand grip strength (HGS) was measured and hand functions were evaluated using the Duruöz Hand Index (DHI).
Results: There were no significant differences in the age, sex, occupation, body mass index (BMI), or insulin resistance between the groups. A total of 24 (20.9%) patients with PD and eight (14.8%) healthy controls had CTS (p=0.349). Hand functions were worse in the PD patients than the control group (p=0.044). Age, occupation, BMI, insulin resistance, OGTT at 0 and 2 h, and HbA1c values were similar between the PD patients with or without CTS.
Conclusion: Our study, for the first time, reveals that CTS is slightly more common and hand functions are impaired in PD compared to the healthy individuals. Based on these findings, we suggest that hand functions should be evaluated in PD patients.
Sympathetic skin responses and electromyographic reaction times in chronic autoimmune thyroiditis: An overlooked electrodiagnostic study
Authors: Ümit Yemişci Oya , Özen Selin , Öztürk Şişman Tubanur , Anıl Cüneyd , Nur Saraçgil Coşar Sacide 
Published: March 2022

Objectives: This study aims to evaluate peripheral nerve functions, sympathetic skin responses (SSRs), and electromyographic (EMG) reaction times in hypothyroid patients and to compare them to healthy individuals.
Patients and methods: Between January 2007 and September 2007, a total of 54 patients with Hashimoto’s thyroiditis including 35 euthyroid (3 males, 32 females; mean age: 45.2±10.2 years; range, 35 to 60 years) and 19 with subclinical hypothyroidism (2 males, 17 females; mean age: 43.2±12.6 years; range, 40 to 65 years) were included in the study. The control group consisted of 35 healthy individuals (5 males, 30 females; mean age: 39.1±9.3 years; range, 29 to 52 years). Nerve conduction studies (NCSs), SSRs of the hand and foot obtained by stimulation of the contralateral median nerve, and EMG reaction times of the extensor indicis proprius muscle were performed in all subjects.
Results: There was no significant difference in peripheral NCSs and SSRs between patients and the control group. However, reaction times were longer in the AIT patients compared to the healthy individuals suggesting alterations in cognitive function related to the primary disease process in AIT.
Conclusion: Electrodiagnosis of autonomic nervous system involvement and cognitive impairment can be challenging in AIT. However, EMG reaction times and SSRs are practical and useful tools that are often overlooked. On the other hand, SSRs may be combined with more quantitative tests, such as sudomotor axon reflex testing, to allow us to better determine the extent of involvement of the autonomic nervous system in AIT.
Physical therapy versus radial extracorporeal shock wave therapy in the treatment of carpal tunnel syndrome: A randomized-controlled study
Authors: Sağlam Gonca , Çetinkaya Alişar Dilek , Özen Selin 
Published: March 2022

Objectives: This study aims to compare the efficacy of physical therapy (PT) and radial extracorporeal shock wave therapy (rESWT) in the treatment of carpal tunnel syndrome (CTS).Patients and methods: Between May 2020 and July 2020, a total of 125 wrists of 95 patients (22 males, 73 females; mean age: 54.3±11.3 years; range, 19 to 69 years) with mild-to-moderate CTS were allocated into three groups and evaluated. The control group (Group 1, n=42) was treated with splinting and an exercise program. Group 2 (n=42) was treated with a total of three sessions of rESWT, splinting and an exercise program. Group 3 (n=41) was treated with a total of 15 sessions of PT modalities, splinting, and an exercise program. Each patient was evaluated before, three weeks and 12 weeks after treatment using a Visual Analog Scale (VAS), the Boston Carpal Tunnel Questionnaire (BCTQ), the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) Pain Scale, and electrodiagnostic testing.Results: The reduction in VAS, BCTQ, LANSS, and improvement in sensory nerve conduction velocity were significantly greater at three and 12 weeks of follow-up in Groups 2 and 3, compared to Group 1 (p<0.001). A greater improvement was observed in all clinical parameters in Group 2, compared to Group 3 (p<0.001).Conclusion: This is the first study to compare the treatment outcomes of PT and rESWT in the treatment of CTS. The results of this study show that both PT and rESWT are effective in the treatment of CTS; however, rESWT yields superior treatment effects compared to conventional PT. The practicalities of administering rESWT and its efficacy in the treatment of CTS may make it the treatment of choice.
Which Comes First—Acting or Judging?
Authors: Schick Stefan ,   Philosophy Documentation Center
Published: March 2022

It is one of the crucial insights of pragmatism that our judging is itself a discursive practice. Our judgments are normatively determined performances for which we are responsible. Therefore, judgments are a species of action. For in both actions and judgments, we subject ourselves and others to justifiable norms. Since these insights can already be found in Hegel, Hegel is now often interpreted as a champion of pragmatism. Hegel’s logic is thereby mainly understood as the continuation of the Kantian project of transcendental philosophy. Based upon this pragmatist interpretation of Hegel, the paper reads F. H. Jacobi’s philosophy as an alternative pragmatism which is explicitly founded on our life praxis rather than our practice of judgment.
Entrelaçamentos entre algoritmos e têxteis: experimentos em design de moda
Authors: Pires Marianna Ribeiro , Montardo Sandra Portella , Schemes Claudia 
Published: March 2022

Este artigo tem como objetivo identificar aplicações algorítmicas na área do design de moda, pois, atualmente, reconhece-se os algoritmos associados a procedimentos automatizados inerentes à tecnologia digital. Buscamos, também, compreender o seu papel na composição do trabalho criativo envolvido no design de moda, além de contribuir na busca de soluções criativas na concepção de produtos. Esta pesquisa, quanto à sua natureza é aplicada e quanto aos seus objetivos é exploratória. Os procedimentos técnicos utilizados foram a pesquisa bibliográfica sobre a história dos algoritmos e as suas aplicações, além de experimentos de criação manual de texturas têxteis desenvolvidos com base em algoritmos. Conclui-se que a utilização de algoritmos na geração de texturas têxteis é uma ferramenta de criação que auxilia o processo do designer de moda, ampliando a capacidade de autoralidade e concedendo o caráter das artes anuais na concepção de produtos de moda.
NanoForms: an integrated server for processing, analysis and assembly of raw sequencing data of microbial genomes, from Oxford Nanopore technology
Authors: Czmil Anna , Wronski Michal , Czmil Sylwester , Sochacka-Pietal Marta , Cmil Michal , Gawor Jan , Wołkowicz Tomasz , Plewczynski Dariusz , Strzalka Dominik , Pietal Michal 
Published: March 2022

Background
Next Generation Sequencing (NGS) techniques dominate today’s landscape of genetics and genomics research. Though Illumina still dominates worldwide sequencing, Oxford Nanopore is one of the leading technologies currently being used by biologists, medics and geneticists across various applications. Oxford Nanopore is automated and relatively simple for conducting experiments, but generates gigabytes of raw data, to be processed by often ambiguous set of alternative bioinformatics command-line tools, and genomics frameworks which require a knowledge of bioinformatics to run.

Results
We established an inter-collegiate collaboration across experimentalists and bioinformaticians in order to provide a novel bioinformatics tool, free for academics. This tool allows people without extensive bioinformatics knowledge to simply process their raw genome sequencing data. Currently, due to ICT resources’ maintenance reasons, our server is only capable of handling small genomes (up to 15 Mb). In this paper, we introduce our tool, NanoForms: an intuitive and integrated web server for the processing and analysis of raw prokaryotic genome data, coming from Oxford Nanopore. NanoForms is freely available for academics at the following locations: http://nanoforms.tech (webserver) and https://github.com/czmilanna/nanoforms (GitHub source repository).
Factors Favoring the Toxic Effects of Metformin in Subjects with Type 2 Diabetes in Two Referral Hospital in Douala, Cameroon
Authors: Manaoda Antoine Vayaraï , Fuh Azinwi Ngumsi , Yinyang Jacques , Ngene Jean Pierre , Loe Gisele Etame , Adiogo Dieudonné 
Published: March 2022

Introduction: The Metformin is a first line agent for the treatment of type 2 diabetes that can be used alone or in combination with sulfonylureas thiazolidinediones, incretin-based drugs, sodium/glucose cotransporter-2 inhibitors, or other hypoglycemic agents. Metformin is the most used anti-hyperglycemic agent for the treatment of Type 2 Diabetes Mellitus. It is considered as a very good drug, with low risk and high benefit. The Metformin liver and pancreatic intoxication can be due to massive ingestion or to a progressive accumulation due to renal failure, hence an elevated blood amylase and transaminases levels. Fatal cases due to metformin intoxication have been described.
Methods: The study was an analytical cross sectional study which was carried out in the Douala General Hospital and the Douala Laquintinie Hospital from the 1st of March 2021 to the 30th of May 2021. Our study population included type 2 diabetic patients above 40years of age who are strictly on oral antidiabetic drugs who came to consult in the Douala General Hospital and the Douala Laquintinie Hospital, the exclusion criteria were; Patients infected with hepatitis A, B or hepatitis C, diabetic patients suffering from other pathologies like fatty liver disease and cirrhosis, liver cancer and others, patients suffering from terminal renal failure, patients who have been on NSAI drugs for long period and also taking alcohol or those with hemolyzed blood. For ethical consideration, after presenting and filling of the consent form, 5ml of blood was collected from each participant for the analyses, serum was conserved at a temperature of -15 to -20oC and the samples were finally analyzed in 2 series on the Biotecnica 1500 chemistry analyzer. Statistical analysis was done on Microsoft Excel 2013 version.
Results: A total of 102 participants were enrolled, female gender was dominant, and the mean age was 69 years. Most of participants felt under neurological clinical effects (tiredness, dizziness, and tingling sensation). We had an average GOT of 28.3, with a minimum of 7.0 and a maximum of 207, an average GPT of 19.8 with a minimum of 5.9 and a maximum of 90.7 and an average amylase was 45.7 with a minimum value of 11.5 and a maximum value of 470. On the other hand, our average GFR was 74.3 with a minimum of 12.8 and a maximum of 153.2. From the study population, 90 where on metformin among which 79 were on stages 2-5 of kidney failure.
Conclusion: This study highlights the risk of liver toxicity for diabetic patient under metformin surfing from renal failure.
Testing effects of social rejection on aggressive and prosocial behavior: A meta‐analysis
Authors: Quarmley Megan , Feldman Julia , Grossman Hannah , Clarkson Tessa , Moyer Anne , Jarcho Johanna M. 
Published: March 2022

AbstractSocial rejection elicits profound feelings of distress. From an evolutionary perspective, the best way to alleviate this distress is to behave prosocially, minimizing the likelihood of further exclusion. Yet, examples ranging from the playground to the pub suggest rejection commonly elicits aggression. Opposing theoretical perspectives and discordant empirical results have left a basic question unanswered: does rejection more commonly elicit prosocial or aggressive behavior? We conducted three meta‐analyses (one with studies measuring aggressive behavior; one with studies measuring prosocial behavior; and one with studies measuring both aggressive and prosocial behavior; N = 3864) to quantify: (1) the extent to which social rejection elicits prosocial or aggressive behavior and (2) potential moderating effects on these relations. Random‐effects models revealed medium effects such that social rejection potentiated aggressive behavior (k = 19; d = 0.41, p < .0001) and attenuated prosocial behavior (k = 7; d = 0.59, p < .0001), an effect that remained consistent even when participants were given the option to behave prosocially or aggressively (k =  15; d = 0.71, p < .0001). These results cast doubt on the theory that rejection triggers prosocial behavior, and instead suggest it is a robust elicitor of aggression.Statement of Relevance: To our knowledge, these meta‐analyses are the first to directly test whether social rejection elicits aggressive or prosocial behavior. By including a comprehensive collection of both published and unpublished research studies, and examining a wide variety of previously untested moderators, we show that social rejection robustly elicits aggressive behavior and inhibits prosocial behavior. Additionally, we demonstrate that aggressive behavior following social rejection is not simply a function of limited choices in response options. In fact, aggressive behavior was evoked even when the option to engage in prosocial behavior was provided. Furthermore, we conducted a comprehensive narrative review of the neural mechanisms underlying social rejection‐elicited aggressive and prosocial behavior to supplement primary analyses. Overall, we believe that our work makes a critical theoretical contribution to the field.
Loss of Productivity‐Adjusted Life‐Years in Working‐Age Australians Due to Knee Osteoarthritis: A Life‐Table Modeling Approach
Authors: Jin Xingzhong , Ackerman Ilana N. , Ademi Zanfina 
Published: March 2022

ObjectiveProductivity‐adjusted life‐years (PALYs) offers a novel approach for quantifying the productivity burden of chronic conditions at the population level over the working lifespan. This study was undertaken to estimate the productivity burden of knee osteoarthritis (KOA) among working‐age Australians, defined as lost PALYs and lost gross domestic product (GDP).MethodsA static life‐table model was constructed to simulate the experiences of working Australians (between the ages of 15–64 years) with KOA and those without KOA, with follow‐up to 65 years (retirement age), a 1‐year cycle length, and an annual discount rate of 5%. KOA prevalence data were obtained from the 2019 Global Burden of Diseases, Injuries, and Risk Factors study. Demographic and mortality data were sourced from the Australian Bureau of Statistics. Health utilities and productivity indices were derived from published sources. Population‐level losses in years of life, quality‐adjusted life‐years (QALYs), and PALYs attributable to KOA were estimated by comparing estimates in the KOA cohort to the no KOA cohort.ResultsIn 2019, a total of 913,539 working‐age Australians were estimated to have KOA, with an overall prevalence of 5.5% (4.5% in men and 6.5% in women). By retirement age, KOA was associated with 39,602 excess deaths, 125,651 years of life lost, 1,938,059 QALYs lost, and 1,943,287 PALYs lost. The economic impact of lost productivity due to KOA amounted to 424 billion Australian dollars in lost GDP.ConclusionOur modeling demonstrates a significant economic burden of KOA among the working Australian population, with marked productivity loss. Our findings highlight the need for public health funding and scalable population‐level strategies for effective KOA prevention and support to maintain productive working.
The Coupling of Local Strain and K+‐Ion Release Induced Phase Transition Heterogeneity in Tunnel MnO2
Authors: Peng Haoyang , Xia Fanjie , Zhang Chenyu , Zhuo Haoxiang , Peng Xin , Song Peihao , Sun Congli , Wu Jinsong 
Published: March 2022

AbstractThe structure and valence transitions in multi‐valent transition metal oxides are closely associated with the intrinsic functionalities that exhibit wide applications in various fields, such as rechargeable batteries, supercapacitors, and catalysis. The internal strain due to intercalated and then released alkali‐ions and defects plays a critical role in tuning the energetically close correlated structures. However, such an effect is still elusive due to its fast dynamics at the atomic scale that requires both high temporal and spatial resolution. Herein, a chip‐based in situ scanning transmission electron microscope investigation is conducted, in which an abnormal tunnel to layered transition within a single MnO2 nanowire is observed. The internal strain initiates a Jahn–Teller active Mn3+ transition to facilitate the Mn migration, which significantly reduces the Mn migration barrier and kinetically favors this abnormal transition. This work provides an atomistic insight into a strain effect in tuning the multi‐phase and valence transitions in the functional metal oxides, e.g., the phase transition in MnO2 during K+‐ion extraction for K+‐ion batteries.
Bio‐Based Solar Energy Harvesting for Onsite Mobile Optical Temperature Sensing in Smart Cities
Authors: Correia Sandra F.H. , Bastos Ana R.N. , Martins Margarida , Macário Inês P.E. , Veloso Telma , Pereira Joana L. , Coutinho João A.P. , Ventura Sónia P.M. , André Paulo S. , Ferreira Rute A.S. 
Published: March 2022

AbstractThe Internet of Things (IoT) fosters the development of smart city systems for sustainable living and increases comfort for people. One of the current challenges for sustainable buildings is the optimization of energy management. Temperature monitoring in buildings is of prime importance, as heating account for a great part of the total energy consumption. Here, a solar optical temperature sensor is presented with a thermal sensitivity of up to 1.23% °C−1 based on sustainable aqueous solutions of enhanced green fluorescent protein and C‐phycocyanin from biological feedstocks. These photonic sensors are presented under the configuration of luminescent solar concentrators widely proposed as a solution to integrate energy‐generating devices in buildings, as windows or façades. The developed mobile sensor is inserted in IoT context through the development of a self‐powered system able to measure, record, and send data to a user‐friendly website.
Essential Role of Triplet Diradical Character for Large Magnetoresistance in Quinoidal Organic Semiconductor with High Electron Mobility
Authors: Wang Chao , Hao Hua , Tajima Keisuke 
Published: March 2022

AbstractA diradicaloid molecule with high semiconducting performance is synthesized based on the quinoidal benzo[1,2‐b:4,5‐b′]dithiophene structure. The diradical character is investigated by quantum chemical calculations and variable temperature electron spin resonance. The diode devices based on this molecule show a large change in electric current in magnetic fields below 100 mT with a strong dependence on the measurement temperatures; as the population of the triplet diradicals increases at high temperatures, the magnetoconductance (MC) values increase. As a result, a MC of −19.4% is achieved at 120 °C, which is the largest negative MC observed for organic molecules to date. In contrast, a smaller diradicaloid molecule based on quinoidal thieno[3,2‐b]thiophene without thermally accessible triplet state shows no MC, indicating the essential role of the triplet diradicals. The strong correlation between the MC and the triplet diradical concentrations suggests that the charge conduction in the diradicaloid is suppressed through a spin‐blocking mechanism, which can be controlled through the magnetic modulation of the hyperfine fields. The compound forms high‐crystallinity thin films and has high monopolar electron transport in organic field‐effect transistors, with an average mobility of 1.01 cm2 V−1 s−1 for edge‐cast films.