bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimizing Local Anaesthetic Practice: Addressing Misconceptions and Minimizing Anaesthetic Failures
Authors: Oghabi Negin , Renton Tara 
Published: January 2022

Local anaesthesia is a sine qua non for pain management in dentistry. Optimizing local anaesthesia practice reduces intra-operative pain, and ultimately ameliorates patient comfort. Many patients still report experiencing intra-operative pain despite being anaesthetized. This is commonplace with inferior alveolar nerve blocks, the current routine approach to mandibular anaesthesia. This technique has been shown, in many cases, to fail at first attempt and can be uncomfortable for patients. It has a higher positive-aspiration rate than other techniques, increasing the risk of systemic complications.CPD/Clinical Relevance: Clinicians should be aware of more effective techniques for mandibular anaesthesia for optimal and safe pain management, and ultimately a better patient experience.
The Use of a Gothic Arch Tracing to Record Centric Relation in the Construction of Complete Dentures
Authors: Strain Kenneth J , Hoyle Philippa , Ali Zaid , Bonsor Stephen J 
Published: January 2022

The establishment of a fixed and reproducible reference point (centric relation) is critical when reorganizing the occlusion in a dentate patient or constructing complete dentures in an edentulous patient. There are many techniques for guiding the patient's mandible into centric relation and recording the relationship between the maxilla and mandible in this position. Some patients are resistant to being manipulated into this position and have an unreproducible habitual path of closure. A gothic arch tracing is considered to be the most reliable and predictable method of determining centric relation. The present article describes the gothic arch tracing technique and illustrates its use in an edentulous patient during the construction of complete dentures.CPD/Clinical Relevance: The gothic arch technique can be used to predictably locate centric relation in both dentate and edentulous patients.
Development of a core outcome set for the orthopaedic management of spinal dysraphism
Authors: Leo Donato G. , Green Gemma , Eastwood Deborah M. , Bridgens Anna , Gelfer Yael 
Published: January 2022

Aims The aim of this study is to define a core outcome set (COS) to allow consistency in outcome reporting amongst studies investigating the management of orthopaedic treatment in children with spinal dysraphism (SD). Methods Relevant outcomes will be identified in a four-stage process from both the literature and key stakeholders (patients, their families, and clinical professionals). Previous outcomes used in clinical studies will be identified through a systematic review of the literature, and each outcome will be assigned to one of the five core areas, defined by the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT). Additional possible outcomes will be identified through consultation with patients affected by SD and their families. Results Outcomes identified in these stages will be included in a two-round Delphi process that will involve key stakeholders in the management of SD. A final list including the identified outcomes will then be summarized in a consensus meeting attended by representatives of the key stakeholders groups. Conclusion The best approach to provision of orthopaedic care in patients with SD is yet to be decided. The reporting of different outcomes to define success among studies, often based on personal preferences and local culture, has made it difficult to compare the effect of treatments for this condition. The development of a COS for orthopaedic management in SD will enable meaningful reporting and facilitate comparisons in future clinical trials, thereby assisting complex decision-making in the clinical management of these children. Cite this article: Bone Jt Open 2022;3(1):54–60.
Terahertz bound states in the continuum with incident angle robustness induced by a dual period metagrating
Authors: Shi Wenqiao , Gu Jianqiang , Zhang Xingyuan , Xu Quan , Han Jiaguang , Yang Quanlong , Cong Longqing , Zhang Weili 
Published: January 2022

Metasurface-empowered bound state in the continuum (BIC) provides a unique route for fascinating functional devices with infinitely high quality factors. This method is particularly attractive to the terahertz community because it may essentially solve the deficiencies in terahertz filters, sensors, lasers, and nonlinear sources. However, most BIC metasurfaces are limited to specified incident angles that seriously dim their application prospects. Here, we propose that a dual-period dielectric metagrating can support multiple families of BICs that originate from guided mode resonances in the dielectric grating and exhibit infinite quality factors at arbitrarily tilted incidence. This robustness was analyzed based on the Bloch theory and verified at tilted incident angles. We also demonstrate that inducing geometric asymmetry is an efficient way to manipulate the leakage and coupling of these BICs, which can mimic the electromagnetically induced transparency (EIT) effect in our dual-period metagrating. In this demonstration, a slow-light effect with a measured group delay of 117 ps was achieved. The incidence-insensitive BICs proposed here may greatly extend the application scenarios of the BIC effect. The high

Q

factor and outstanding slow-light effect in the metagrating show exciting prospects in realizing high-performance filters, sensors, and modulators for prompting terahertz applications.
Maternal depressive symptoms, attendance of sessions and reduction of home safety problems in a randomized toddler safety promotion intervention trial: A latent class analysis
Authors: Wang Yan , Zhu Eric , Hager Erin R. , Black Maureen M. 
Published: January 2022

Objective
Little is known about the association between maternal depressive symptoms and attendance at safety promotion interventions. This study used latent class analysis (LCA) to identify the profile of attendance within a toddler safety intervention and assessed its relation with maternal depressive symptoms at baseline and reduction of home safety problems over time, separately.

Methods
The analytic sample included 91 mothers of toddlers (mean maternal age 28.16 years) who were assigned to the safety promotion intervention group as part of a randomized trial and assessed at baseline, 6-month and 12-month follow-ups. Using LCA, we classified mothers into low and high attendance classes based on their attendance at 8 intervention sessions. We assessed maternal depressive symptoms with the Beck Depression Inventory (BDI) and home safety problems with a 9-item home safety problem observation.

Results
The mothers were classified into low attendance (45%) and high attendance classes (55%). The posterior probability of attending each session ranged from 0–0.29 for the low attendance class and 0.68–0.92 for the high attendance class. Each one unit increase of BDI sum score at baseline was associated with an 8% reduced odds of being in the high attendance class (aOR = 0.92, 95% CI: 0.86, 1.00, p = 0.037). The home safety problem score reduction was greater among high attendance class participants than low attendance class participants at the 6-month follow-up (b = -1.15, 95% CI:-2.09, -0.20, p = 0.018).

Conclusion
Maternal depressive symptoms were associated with the reduced probability of maternal attendance at toddler safety promotion sessions; high session attendance was related to greater reduction of toddler home safety problems. Identifying risk factors for maternal low attendance to interventions and developing strategies to promote attendance should lead to reductions in home safety problems and reductions in unintentional injuries among young children.
Lisdexamfetamine-Induced Ischemic Colitis
Authors: El Joud Karim Abou , Abbasi Misha , Alajati Bana 
Published: January 2022

ABSTRACT
Gastrointestinal bleeding secondary to ischemic colitis (IC) is relatively infrequent. Drug-related etiologies of nonocclusive IC are very rare. Sympathomimetics have been reported to cause IC, with most cases being associated with the illicit use of amphetamines and methamphetamines. There are also a few reported cases of prescription dextroamphetamine-linked IC. However, there are no reported cases of lisdexamfetamine-linked IC. We exhibit a 32-year-old woman presenting with hematochezia after the use of lisdexamfetamine. Colonoscopy findings in this patient were suggestive of IC. In the absence of risk factors, the cause was attributed to the usage of lisdexamfetamine. The patient was managed conservatively and advised to discontinue the medication.
Endoscopic Ultrasound–Guided Gastrojejunostomy for Malignant Gastric Outlet Obstruction in a Patient With a Previous Liver Transplant and Pancreaticoduodenectomy
Authors: On Wei , Huggett Matthew T. , Upasani Vivek , Paranandi Bharat 
Published: January 2022

ABSTRACT
A 29-year-old man underwent a liver transplant 5 years earlier for primary sclerosing cholangitis and a subsequent completion pancreaticoduodenectomy after the discovery of a cholangiocarcinoma on histological analysis of his explant. He presented with gastric outlet obstruction secondary to recurrent peritoneal malignant disease–causing extrinsic compression at the gastroenterostomy site. After multidisciplinary team discussions, an endoscopic ultrasound–guided gastrojejunostomy was performed, resulting in technical and clinical success. We report the first application of endoscopic ultrasound–guided gastrojejunostomy in a patient with the aforementioned postsurgical anatomy.
Maritime pine land use environmental impact evolution in the context of life cycle assessment
Authors: Ferreira José , Esteves Bruno , Cruz-Lopes Luísa P. , Domingos Idalina 
Published: January 2022

Abstract
Between 2005 and 2015, the forest area occupied by maritime pine trees in Continental Portugal decreased by about 10.6%, and the existing volume decreased by about 18.4% mainly due to fires and pests (e.g., nematode) that occurred during this period. The purpose of this study was to study the evolution of the land use environmental impact of 1 m3 of maritime pine, standing in Portuguese forest, during that period using the model by Milà i Canals based on soil organic matter measured by soil organic carbon. Results show that the land use impact category increased from 16,812 kg C deficit in 2005 to 18,423 kg C deficit in 2015. Land transformation to forest roads is the main contribution for land use impact representing 54% of the total value followed by land occupation as forest that represents about 40%.
Mouse Lines with Cre-Mediated Recombination in Retinal Amacrine Cells
Authors: Göz Aytürk Didem , You Wenjia , Cepko Constance L. 
Published: January 2022

AbstractAmacrine cells (ACs) are the most diverse neuronal cell type in the vertebrate retina. Yet little is known about the contribution of ACs to visual processing and retinal disease. A major challenge in evaluating AC function is genetic accessibility. A classic tool of mouse genetics, Cre-mediated recombination, can provide such access. We have screened existing genetically-modified mouse strains and identified multiple candidates that express Cre-recombinase in subsets of retinal ACs. The Cre-expressing mice were crossed to fluorescent-reporter mice to assay Cre expression. In addition, a Cre-dependent fluorescent reporter plasmid was electroporated into the subretinal space of Cre strains. Herein, we report three mouse lines (Tac1::IRES-cre,Camk2a-cre, andScx-cre) that express Cre recombinase in sub-populations of ACs. In two of these lines, recombination occurred in multiple AC types and a small number of other retinal cell types, while recombination in theCamk2a-creline appears specific to a morphologically distinct AC. We anticipate that these characterized mouse lines will be valuable tools to the community of researchers who study retinal biology and disease.
KIFC1 Regulates the Trajectory of Neuronal Migration
Authors: Muralidharan Hemalatha , Guha Shrobona , Madugula Kiran , Patil Ankita , Bennison Sarah A. , Sun Xiaohuan , Toyo-oka Kazuhito , Baas Peter W. 
Published: January 2022

During neuronal migration, forces generated by cytoplasmic dynein yank on microtubules extending from the centrosome into the leading process and move the nucleus along microtubules that extend behind the centrosome. Scaffolds, such as radial glia, guide neuronal migration outward from the ventricles, but little is known about the internal machinery that ensures that the soma migrates along its proper path rather than moving backward or off the path. Here we report that depletion of KIFC1, a minus-end-directed kinesin called HSET in humans, causes neurons to migrate off their appropriate path, suggesting that this molecular motor is what ensures fidelity of the trajectory of migration. For these studies, we used rat migratory neuronsin vitroand developing mouse brainin vivo, together with RNA interference and ectopic expression of mutant forms of KIFC1. We found that crosslinking of microtubules into a nonsliding mode by KIFC1 is necessary for dynein-driven forces to achieve sufficient traction to thrust the soma forward. Asymmetric bouts of microtubule sliding driven by KIFC1 thereby enable the soma to tilt in one direction or another, thus providing midcourse corrections that keep the neuron on its appropriate trajectory. KIFC1-driven sliding of microtubules further assists neurons in remaining on their appropriate path by allowing the nucleus to rotate directionally as it moves, which is consistent with how we found that KIFC1 contributes to interkinetic nuclear migration at an earlier stage of neuronal development.SIGNIFICANCE STATEMENTResolving the mechanisms of neuronal migration is medically important because many developmental disorders of the brain involve flaws in neuronal migration and because deployment of newly born neurons may be important in the adult for cognition and memory. Drugs that inhibit KIFC1 are candidates for chemotherapy and therefore should be used with caution if they are allowed to enter the brain.
Lymph node ratio is superior to AJCC N stage for predicting recurrence in papillary thyroid carcinoma
Authors: Parvathareddy Sandeep Kumar , Siraj Abdul K , Qadri Zeeshan , Ahmed Saeeda O , DeVera Felisa , Al-Sobhi Saif , Al-Dayel Fouad , Al-Kuraya Khawla S 
Published: January 2022

Objective
Recently, lymph node ratio (LNR) has emerged as an alternative to American Joint Committee on Cancer (AJCC) N stage, with superior prognostic value. The utility of LNR in Middle Eastern papillary thyroid carcinoma (PTC) remains unknown. Therefore, we retrospectively analyzed a large cohort of 1407 PTC patients for clinicopathological associations of LNR.

Methods
Receiver operating characteristics (ROC) curve was used to determine the cut-off for LNR. We also performed multivariate logistic regression analysis to determine whether LNR or AJCC N stage was superior in predicting recurrence in PTC.

Results
Based on ROC curve analysis, a cut-off of 0.15 was chosen for LNR. High LNR was significantly associated with adverse clinicopathological characteristics such as male sex, extrathyroidal extension, lymphovascular invasion, multifocality, bilateral tumors, T4 tumors, lateral lymph node (N1b) involvement, distant metastasis, advanced tumor stage, American Thyroid Association (ATA) high-risk category and tumor recurrence. On multivariate analysis, we found that LNR was a better predictor of tumor recurrence than AJCC N stage (odds ratio: 1.96 vs 1.30; P value: 0.0184 vs 0.3831). We also found that LNR combined with TNM stage and ATA risk category improved the prediction of recurrence-free survival, compared to TNM stage or ATA risk category alone.

Conclusions
The present study suggests LNR is an independent predictor of recurrence in Middle Eastern PTC. Integration of LNR with 8th edition AJCC TNM staging system and ATA risk stratification will improve the accuracy to predict recurrence in Middle Eastern PTC and help in tailoring treatment and surveillance strategies in these patients.
Teachers’ Insights on the Development of Personal Competence of Pupils with Visual Impairments in Music Schools
Authors: Žuk-Butkuvienė Aleksandra 
Published: January 2022

According to the legal acts of the European Union and Lithuania regulating the aims and peculiarities of the organization of education, non-formal education and learning and educational assistance for pupils with special educational needs, scientific research of Lithuanian and foreign authors, it can be stated that musical activity for pupils with special educational needs benefits revealing and strengthening of their personal competence. However, the research on development of personal competence through non-formal and formal education, complemented with music and art programs for children with special needs, especially students with visual impairments, is insufficient. The aim of the research is to reveal teachers’ insights on the development of personal competence of pupils with visual impairments in music schools. To reveal the aim of this work and to reach its goals qualitative research based on qualitative content analysis is used. The methods to collect information are: semi-structured interviews and monitoring. Personal competence can be defined as corresponding components, that make up three types of skills: self-understanding (well-being, self-expression, independence), self-evaluation (self-assessment, self-esteem, self-confidence), self-control (self-regulation, decision-making, responsibility, sociability). The results of the semi-structured interview with 5 teachers suggest that purposeful development of personal competence of pupils with visual impairments can help to create and implement already existing social skills, to strengthen and expand them with practical experience. Music schools have an opportunity to educate pupils with visual impairments by individualizing curricula, enabling them to disclose their talents and meeting their individual needs for self-expression, nurturing innate powers, preparing for autonomous life, understanding common values, which will later be used as a framework for their future lives.
Bosques de coral negro del Área de Conservación Guanacaste, Costa Rica: especies y distribución
Authors: Matamoros-Calderón Wendolyn , Lara Minor , Breedy Odalisca 
Published: January 2022

Introduction: Little is known about the antipatharians in Costa Rica, only three species are known from the Pacific and the occurrence of coral forests was previously reported only for Isla del Coco. Black coral forests were observed at several sites in the north Pacific of the country, within the Guanacaste Conservation Area (ACG), which are reported and characterized in this study.
Objective: To determine the species of black corals present in the ACG Marine Sector and its surroundings, and geographically locate the sites where black coral forests grow.
Methods: Visual censuses were made by diving, samples were taken and analyzed in the laboratory for identification.
Results: These black coral forests are composed of two species: Myriopathes panamensis and Antipathes galapagensis, these species are described and illustrated. The coral forests were found within and outside ACG marine protected areas. Myriopathes panamensis was found between 15-35 m depth and A. galapagensis at 30-45 m. Associated macrofauna was observed among the branches of M. panamensis, their ecological importance and status have not been determined.
Conclusions: The species found did not have morphological variations with those described in other similar regions. Associated fauna was found (mainly the anemone Nemanthus californicus, the bivalve Pteria sterna and the longnose hawkfish Oxycirrhithes typus) and needs to be studied to determine its role on black corals. The importance of the ACG as a marine biodiversity conservation site is emphasized.
Treatment for the concerned significant others of gamblers: A systematic review
Authors: Edgren Robert , Pörtfors Pia , Raisamo Susanna , Castrén Sari 
Published: January 2022

Abstract

Background and aims
Research recognizes the extent of harm experienced by concerned significant others (CSOs) of gamblers. This systematic review’s aims are to examine the interventions for CSOs, evaluate potential benefits, and thematically describe treatment processes. The Stress-Strain-Coping-Support model (SSCS) served as the theoretical framework.

Methods
Database searches were conducted in: MEDLINE, CINAHL Complete, Web of Science Core Collection, Social Services Abstracts, Applied Social Science Index and Abstracts, Cochrane Central Register of Controlled Trials, and APA PsycInfo (between 01/Jan 2011–10/Jun 2021). Other search methods were also utilized. Inclusion criteria: interventions for CSOs with CSO specific outcomes. The Evidence Project Risk of Bias Tool was used for assessment.

Results
19/768 records were included. Nine interventions were utilized: 3 CSO directed, 4 for couples, and 2 low threshold online interventions. A quantitative synthesis (N = 7 studies) of effect size estimates for depression and anxiety measures didn’t indicate any intervention to have better outcomes than others. Core themes in the treatment process identified in the qualitative synthesis (N = 7) included: information and understanding, social support, coping skills, communication, and strain. Limitations in the evidence related to sampling, control-conditions and outcome measurements.

Discussion and conclusion
Several interventions were identified, yet no specific interventions appeared more beneficial than others. Using the SSCS model, commonalities and differences in intervention content were identified, along with themes that influence treatment processes. The need for tailored interventions is discussed. Future treatment efficacy research should carefully select study designs and outcome measurements. PROSPERO (CRD42021229408).
Muhammadiyah constitution jihad movement: a case study of the Omnibus Law on job creation
Authors: Huda Muhammad Nurul , Hammam Hammam , Suranto Suranto , Saputra Herdin Arie 
Published: January 2022

The Omnibus Law on job creation is a government initiative proposal and it has drawn public reactions to polemics of debate. Muhammadiyah as a religious organisation also expressed their objections to the Omnibus Law on job creation. This article is qualitative research that applies NVivio 12 plus to manage the data through crosstab analysis and cluster analysis. This study shows that there are aspects of conflictual relations that give rise to a movement. Muhammadiyah forms a formal or non-formal organization that involves the Law and Human Rights Council (HAM) as well as s a forum of the dean of the law faculty and the head of the law school of Muhammadiyah and Aisyiyah universities. In the concept, of Muhammadiyah emphasizes to synchronise between institutions by prioritizing transparency, making laws severe in their implementation. Muhammdiyah offers three concept points, namely revoking a government regulation in lieu of law (PERPU), delaying its implementation, and revising through public participation.