bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sentinel Lymph Node Mapping in Breast Cancer Patients Through Fluorescent Imaging Using Indocyanine Green
Authors: Bargon Claudia A. , Huibers Anne , Young-Afat Danny A. , Jansen Britt A.M. , Borel-Rinkes Inne H.M. , Lavalaye Jules , van Slooten Henk-Jan , Verkooijen Helena M. , van Swol Christiaan F.P. , Doeksen Annemiek 
Published: July 2022

Objective:
The aim was to compare the (sentinel) lymph node detection rate of indocyanine green (ICG)-fluorescent imaging versus standard-of-care 99mTc-nanocoilloid for sentinel lymph node (SLN)-mapping.

Background:
The current gold standard for axillary staging in patients with breast cancer is sentinel lymph node biopsy (SLNB) using radio-guided surgery using radioisotope technetium (99mTc), sometimes combined with blue dye. A promising alternative is fluorescent imaging using ICG.

Methods:
In this noninferiority trial, we enrolled 102 consecutive patients with invasive early-stage, clinically node-negative breast cancer. Patients were planned for breast conserving surgery and SLNB between August 2020 and June 2021. The day or morning before surgery, patients were injected with 99mTc-nanocolloid. In each patient, SLNB was first performed using ICG-fluorescent imaging, after which excised lymph nodes were tested with the gamma-probe for 99mTc-uptake ex vivo, and the axilla was checked for residual 99mTc-activity. The detection rate was defined as the proportion of patients in whom at least 1 (S)LN was detected with either tracer.

Results:
In total, 103 SLNBs were analyzed. The detection rate of ICG-fluorescence was 96.1% [95% confidence interval (95% CI)=90.4%–98.9%] versus 86.4% (95% CI=78.3%–92.4%) for 99mTc-nanocoilloid. The detection rate for pathological lymph nodes was 86.7% (95% CI=59.5%–98.3%) for both ICG and 99mTc-nanocoilloid. A median of 2 lymph nodes were removed. ICG-fluorescent imaging did not increase detection time. No adverse events were observed.

Conclusions:
ICG-fluorescence showed a higher (S)LN detection rate than 99mTc-nanocoilloid, and equal detection rate for pathological (S)LNs. ICG-fluorescence may be used as a safe and effective alternative to 99mTc-nanocoilloid for SLNB in patients with early-stage breast cancer.
Sex Disparities in Outcomes Following Major Liver Surgery
Authors: Birrer Dominique L. , Linecker Michael , López-López Víctor , Brusadin Roberto , Navarro-Barrios Álvaro , Reese Tim , Arbabzadah Sahar , Balci Deniz , Malago Massimo , Machado Marcel A. , Ardiles Victoria , Soubrane Olivier , Hernandez-Alejandro Roberto , de Santibañes Eduardo , Oldhafer Karl J. , Popescu Irinel , Humar Bostjan , Clavien Pierre-Alain , Robles-Campos Ricardo 
Published: July 2022

Aim:
To explore potential sex differences in outcomes and regenerative parameters post major hepatectomies.

Background:
Although controversial, sex differences in liver regeneration have been reported for animals. Whether sex disparity exists in human liver regeneration is unknown.

Methods:
Data from consecutive hepatectomy patients (55 females, 67 males) and from the international ALPPS (Associating-Liver-Partition-and-Portal-vein-ligation-for-Staged-hepatectomy, a two stage hepatectomy) registry (449 females, 729 males) were analyzed. Endpoints were severe morbidity (≥3b Clavien-Dindo grades), Model for End-stage Liver Disease (MELD) scores, and ALPPS interstage intervals. For validation and mechanistic insight, female-male ALPSS mouse models were established. t, χ2, or Mann-Whitney tests were used for comparisons. Univariate/multivariate analyses were performed with sensitivity inclusion.

Results:
Following major hepatectomy (Hx), males had more severe complications (P=0.03) and higher liver dysfunction (MELD) P=0.0001) than females. Multivariate analysis established male sex as a predictor of complications after ALPPS stage 1 (odds ratio=1.78; 95% confidence interval: 1.126–2.89; P=0.01), and of enhanced liver dysfunction after stage 2 (odds ratio=1.93; 95% confidence interval: 1.01–3.69; P=0.045). Female patients displayed shorter interstage intervals (<2 weeks, 64% females versus 56% males, P=0.01), however, not in postmenopausal subgroups. In mice, females regenerated faster than males after ALPPS stage 1, an effect that was lost upon estrogen antagonism.

Conclusions:
Poorer outcomes after major surgery in males and shorter ALPPS interstage intervals in females not necessarily suggest a superior regenerative capacity of female liver. The loss of interstage advantages in postmenopausal women and the mouse experiments point to estrogen as the driver behind these sex disparities. Estrogen’s benefits call for an assessment in postmenopausal women, and perhaps men, undergoing major liver surgery.
Association Between Maintenance Immunosuppressive Regimens and COVID-19 Mortality in Kidney Transplant Recipients
Authors: Gérard Alexandre O. , Barbosa Susana , Anglicheau Dany , Couzi Lionel , Hazzan Marc , Thaunat Olivier , Blancho Gilles , Caillard Sophie , Sicard Antoine ,   French SOT COVID Registry
Published: July 2022

Background.
Solid organ transplant recipients are at high risk for fatal forms of coronavirus disease 2019 (COVID-19). We conducted a cohort study among kidney transplant (KT) recipients from the French Solid Organ Transplant COVID-19 Registry to investigate the association between maintenance immunosuppressive drugs and 60-d mortality.

Methods.
Data from all KT recipients with COVID-19 included in the French Solid Organ Transplant COVID-19 Registry between February 28, 2020, and December 30, 2020, were retrieved. We evaluated associations between immunosuppressive drugs and death within 60 d using logistic regression, with all baseline characteristics considered to influence outcome or immunosuppressive regimen. The Benjamini-Hochberg correction was used for controlling false positive rate; 40 multiple imputations were performed. Adjusted P value <0.05 was considered statistically significant.

Results.
There were 1451 KT recipients included. Median age was 58 y, and 66.4% were men. Most frequent comorbidities were hypertension (81.9%), diabetes (34.5%), and cardiovascular disease (29.5%). Median time since transplant was 71 mo. Maintenance immunosuppression regimens included calcineurin inhibitors (1295, 89.2%), antimetabolites (1205, 83%), corticosteroids (1094, 75.4%), mammalian target of rapamycin inhibitors (144, 9.9%), and belatacept (58, 4.0%). Among 1451 transplant recipients, 201 (13.9%) died within 60 d. Older age and higher baseline serum creatinine were associated with mortality (odds ratios, 1.09 [1.07-1.11] and 1.01 [1.005-1.009], P < 0.001). Corticosteroid-free regimens were associated with a significantly lower risk of death (odds ratio, 0.48 [0.31-0.76]; P = 0.011).

Conclusions.
Corticosteroid-free regimens were associated with a lower risk of death in KT recipients with COVID-19. Long-term exposure to corticosteroids impairs immune functions and may predispose solid organ transplant recipients to severe forms of COVID-19.
Local electrochemical corrosion performance of nano-SiC/MAO composite coating on 6061-Al alloy
Authors: Liu Yida , Zhao Jie , Yang Xiaoyu , Gu Yanhong , Yang Zihao 
Published: July 2022

Purpose
The purpose of this paper is to improve the corrosion resistance of the 6061-Al alloy as the battery pack material for electric vehicles, and the nano-SiC/MAO composite coating was prepared.

Design/methodology/approach
The corrosion resistance of coatings was evaluated by the global electrochemical test, and the local electrochemical impedance spectroscopy (LEIS) was used to study the local corrosion mechanism. The laser confocal microscope, scanning electron microscope and X-ray diffractometer (XRD) were used to characterise coatings.

Findings
Results showed that the impedance of nano-SiC/MAO coating was 1–2 times higher than MAO coating, and the main corrosion product was Al(OH)3. LEIS results showed that the impedance of the nano-SiC/MAO coating was two times higher than the MAO coating. The defective SiC/Micro-arc oxidation coating still had high corrosion resistance compared to the MAO coating.

Originality/value
The physical model of the local corrosion mechanism for SiC/MAO composite coating in “cavity-fracture collapse” mode was proposed.
Fuzzy control of a landing gear system with oleo-pneumatic shock absorber to reduce aircraft vibrations by landing impacts
Authors: Arık Ahmet Enes , Bilgiç Boğaç 
Published: July 2022

Purpose
The purpose of this paper is to control a landing gear system with an oleo-pneumatic shock absorber with the fuzzy controller.

Design/methodology/approach
The landing gear system with an oleo-pneumatic shock absorber is modeled mathematically. A fuzzy controller is designed for reducing aircraft vibrations. Stroke velocity and main mass velocity parameters were used to decide variable gas pressure with the fuzzy controller.

Findings
The fuzzy controller, designed according to stroke velocity and main mass velocity, reduces aircraft vibrations by the landing impacts. The controller can provide strong robustness because it shows similar good performance for different descent speeds.

Research limitations/implications
This study was carried out through simulations in a computer environment and has not been experimentally tested in a real environment. In addition, signal and measurement delays are not taken into account. In future models, the effects of these signal delays can be added, and the controller can be tested on a real model.

Originality/value
In this study, to the best of the authors’ knowledge, for the first time, the gas pressure for the landing gear system using an oleo-pneumatic shock absorber was controlled by a fuzzy controller that adjusts the stroke velocity and the main mass velocity. Although the oleo-pneumatic shock absorber model contains high nonlinearities, the designed fuzzy controller gave successful results as robust.
The role of information architecture in the automation of records in Botswana in an e-government setting
Authors: Mosweu Olefhile , Bwalya Kelvin Joseph 
Published: July 2022

PurposeGovernment entities often implement automated records management systems, often without a clear governing framework to facilitate such automation. This study aims to explore the role played by information architecture (IA) in records automation in Botswana and propose a guiding framework in the context of e-government.Design/methodology/approachThis qualitative study uses a focused literature review to study the importance of IA in records automation in e-government.FindingsWithout proper IA, information organization including retrieval/access to records becomes difficult. Practically, this would practically and negatively affect process automation in e-government solutions.Research limitations/implicationsThe proposed framework can guide e-government record automation in Botswana. However, its limitation lies in the fact that it has not been tested, thereby limiting its practicality until tested empirically.Practical implicationsThe proposed framework can be used to inform record automation management processes in the realm of Botswana’s e-government project.Originality/valueThe proposed framework contributes to the body of knowledge on the automation of records and e-government in Botswana specifically and Africa in general.
Are Chinese MNEs more strongly attracted to global cities and knowledge intensive city clusters than developed market MNEs when undertaking greenfield strategic asset seeking related FDI?
Authors: Wu Ludan , Sutherland Dylan , Peng Xinghao , Anderson John 
Published: July 2022

Purpose
Cities are host to many of the world’s knowledge intensive research and innovation clusters. As such, they are likely to be attractive locations for emerging market multinational enterprises (MNEs) seeking to engage in knowledge seeking “springboard” type firm-level catch-up strategies. The purpose of this study is to therefore explore whether city-based research-intensive clusters containing deep pools of location bounded (i.e. “sticky”) knowledge are a stronger driver for greenfield research and development (R&D)-related FDI projects for Chinese MNEs than they are for developed market MNEs.

Design/methodology/approach
The authors use logistic modelling on 97,163 worldwide greenfield FDI projects to explore the relative likelihoods of Chinese MNEs engaging in R&D-related greenfield (i.e. “strategic asset seeking”) FDI projects as well as how city type (global or research-intensive cluster city) moderates this relationship for Chinese MNEs.

Findings
The authors find that Chinese MNEs are more likely to engage in overseas R&D FDI projects (compared with other types of project) than DMNEs and that research-intensive city clusters hold a stronger attraction for Chinese MNEs than developed market MNEs.

Research limitations/implications
The authors discuss how the research contributes to the debate on emerging market MNE catch-up theory, as well as that on sub-national city location choice, by highlighting the growing importance of sub-national geography to understanding strategic asset seeking related greenfield FDI.

Practical implications
Sub-national city location choice is an important driver of strategic asset seeking FDI for Chinese MNEs, one that both national and local city level policymakers should pay attention to.

Social implications
Chinese FDI via aggressive mergers and acquisitions to acquire key technologies has been restricted in recent years. Policymakers must consider whether they may also wish to restrict Chinese greenfield FDI in R&D-related projects, which now exhibit a pronounced upward trend.

Originality/value
The authors highlight the growing importance of sub-national geography to understanding strategic asset seeking related greenfield FDI in Chinese MNEs (and how it plays, more generally, a central role in their strategies).
Open education resources’ benefits and challenges in the academic world: a systematic review
Authors: Adil Hafiz Muhammad , Ali Shahbaz , Sultan Mussarat , Ashiq Murtaza , Rafiq Muhammad 
Published: July 2022

Purpose
Open educational resources (OERs) are internet-based digital content that is used for academic purposes by instructors, students and researchers in the era of the information economy. Hence, this study aims to systematically review the literature, focusing on OERs’ benefits and challenges in the academic world.

Design/methodology/approach
The relevant literature systematically reviewed following the preferred reporting items for systematic literature reviews and meta-analyses (PRISMA) guidelines. The pertinent literature was obtained from four main scholarly databases, and finally, 21 papers that met the inclusion criteria were included in this study.

Findings
The findings revealed that the key benefits of OERs include expanded access to knowledge, supporting lifelong learning, pedagogical benefits and enhancing students’ learning outcomes. However, the key challenges include lack of time to find appropriate resources, lack of awareness about the usage and copyrights, quality assurance and technological limitations and lack of organizational support.

Practical implications
The practical and policy implications highlight the joint venture of academia and library professionals to help the students evaluating OERs, quality assurance, copyright issues and lifelong learning.

Originality/value
Earlier studies missed few significant insights of OERs, such as they did not address the quality assurance of OERs; the issue of understanding of copy right (creative common license) challenges related with OERs; and lack of time for finding suitable resources. Hence, this study identified significance insights related with OERs.
Impact of commercial, financial and corporate affairs on operational excellence of the Indian mining industry
Authors: Mishra Padma Charan , Panigrahi Rashmi Ranjan , Samantaray Alaka 
Published: July 2022

Purpose
This study aims to identify the impact of commercial issues (CIs), financial issues (FIs) and corporate affairs (CAs) on operational excellence (OE) of the mining industry.

Design/methodology/approach
A purposive sample of size 321 was collected from Indian mining executives with more than ten years of exposure to the mining field. Factors are identified and confirmed with the use of confirmatory factor analysis. The structural equation modeling technique was then applied to understand the unique as well as the complex relationships between FI, CI, CA and OE.

Findings
The results indicate that all three issues, CI, FI and CA, have an influence on OE in the Indian mining industry. Among the variables of the issues considered in this study, marketing products and size and quality of products (from CI); scale of economies (from FI); risk management (from CA); and transportation and machine operation (from OE) are the highest influencing variables.

Research limitations/implications
This study has its limitations in sampling, the timing of sample collection and their mode. The samples were collected from only massively deposited large mines.

Practical implications
Business managers of the mining industry will be more vigilant and aware of those indirect variables such as marketing products, size and quality of products, scale of economies and risk management, which can influence OE apart from major influencing variables such as transportation and machine operations and production scheduling.

Originality/value
To the best of the authors’ knowledge, this is the first study in the mining industry to evaluate the impact of these three issues on OE. The originality of this research lies in testing the CI, FI and CA of the mining industry with OE, which is completely new to this field.
Exploring the role of relationship management and relationship quality in B2B: empirical insights and future research directions
Authors: Lasrado Flevy , Thaichon Park , Nyadzayo Munyaradzi W. 
Published: July 2022

Purpose
In the past few decades, relationship management (RM) theory and RM strategies in business-to-business (B2B) contexts have evolved tremendously, driven by constant innovation. Hence, the purpose of this study is to understand the trends and evolution of RM and relationship quality (RQ) in B2B contexts and empirical insights on RM and RQ in B2B, which in turn would provide insights into trends and future research directions.

Design/methodology/approach
Grounded on the industrial marketing and purchasing group, this study adopts a critical systematic literature review to provide a comprehensive analysis of the past, current and future trends in empirical research insights of RM and RQ in B2B markets.

Findings
This study provides some novel insights into RM in B2B context by using a multidimensional approach to RM and RQ and analyzing prior marketing research from three perspectives: the evolution of RM and RQ in B2B context; prior empirical research; and practical business insights. Overall, these perspectives inform the development of an evolving side of RQ in B2B contexts, leading to some predictions regarding the future of RM in B2B markets.

Practical implications
The exploratory results of this study shed light on the key factors that drive RQ and the importance of RM in B2B markets in the digital age where customers still long for human interaction regardless of the prevalence of advanced technology.

Originality/value
In the wake of advanced technologies and particularly, B2B companies had to turn to virtual platforms and embrace digital transformation to establish and manage their customer relationships. Yet, managing relationships via digital channels has its own challenges for both B2B practitioners and scholars. This indicates that there is still a huge need for attuned RM strategies that align with the changing environments – mainly driven by technological advancement – in B2B markets.
Textual analysis of the annual report and corporate performance: evidence from China
Authors: Alduais Fahd 
Published: July 2022

Purpose
This paper aims to examine the relationship between the readability of annual reports and corporate performance in Chinese listed firms.

Design/methodology/approach
This research examined the annual report readability factors of Chinese listed companies by using a textual analysis method using Python to extract the text from the annual reports, convert it into numerical form to facilitate statistical analysis and then merge the results with data from the Chinese stock market to explain the impact on corporate performance and predict future earnings in the Chinese financial markets from 2008 to 2021.

Findings
Study findings indicate that firms with better financial reporting readability are more profitable, incur lower agency costs and have low earnings in the Chinese stock markets when readability is low (i.e. more complexity and length of annual reports). It was also found that when a listed company has a good performance, it prefers to use a short space to explain its operating and financial status. More generally, the means of the report length are short, and accounting terms are used less frequently; in the case of a poor company, the annual report is particularly long and accounting terms are more frequently used. In the context of the COVID-19 crisis, this study served as a proxy measure of returns prior to the announcement of the COVID-19 pandemic. In addition, an instrumental variable approach is used, which helps results to remain robust and control for fixed effects and potential endogeneity problems.

Research limitations/implications
Although this study’s results cannot be generalised globally because of their limited scope, they can still be generalised across non-English speaking countries. Thus, future cross-country research is encouraged to examine the textual analysis of financial reports across those countries.

Practical implications
This study conveys two messages to investors and policymakers within the Chinese market. First, investors ought to pay greater attention to the nonfinancial information contained in annual reports to improve the accuracy of their predictions regarding future firm performance. Second, Chinese policymakers are encouraged to instate a policy for the use of plain English in annual reports to make them more readable by international investors.

Originality/value
This study contributes to the paucity of research that examines English-written annual reports in non-English speaking countries by examining the readability of annual reports in the Chinese market.
The push, pull, and mooring effects toward switching intention to halal cosmetic products
Authors: Al-Banna Hasan , Jannah Syayyidah Maftuhatul 
Published: July 2022

Purpose
The paper aims to investigate the push, pull and mooring effects towardswitching intention to halal cosmetic products.

Design/methodology/approach
The rapid growth of the halal industry in Muslim and non-Muslim countries opens a new market for cosmetic companies. For Muslims, using halal cosmetics is one of the religious orders, which their behavior relies on religious values. However, consuming nonhalal cosmetic products is still popular among Muslim consumers. The data are gathered through an online self-administered questionnaire. The total sample is 220 Indonesian females with an 88% response rate. Then, partial least squares structural equation modeling is used to analyze the data.

Findings
The result showed that regret, perceived value and religious beliefs influence the switching intention behavior to use halal cosmetics products. While dissatisfaction influences regret, and the brand also influences perceived value.

Originality/value
The paper provides several factors that are still rarely investigated previously in the context of halal cosmetics literature, such as perceived value and brand image (Handriana et al., 2020). Hence, these factors contribute significantly to the intention of Muslim consumers to switch to halal cosmetics.