bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFFICACY OF ACCELERATED STREPTOKINASE INFUSION IN THE TREATMENT OF ST ELEVATION MYOCARDIAL INFARCTION
Authors: Shafiq Umer , Wahab Muhammad Abdul , Rahman Syed Kashif ur 
Published: November 2022

Objectives: Cardiovascular disease (CVD) is considered as one of the important priorities in the health systems of all countries. Approximately 550,000 first episodes and 200,000 recurrent episodes of acute myocardial infarction occur annually worldwide. Globally, ischemic heart disease has become the leading contributor to the burden of disease as assessed on the basis of disability-adjusted life-years. To determine the efficacy of accelerated streptokinase in patients with acute ST elevation myocardial infarction.
Methodology: This Descriptive study was done in the Department of Cardiology, Hayatabad Medical Complex Peshawar from August 2020 to February 2021. Total 144 patients were observed. All patients were subjected to SK in a dose of 1.5million units over 60 minutes. All patients were under strict observation and a repeat ECG was performed to determine the efficacy of accelerated SK.
Results: Our study shows that among 144 patients mean age and standard deviation was 61± 8.19. 88(61%) patients were male and 56(39%) patients were female. More over accelerated streptokinase was effective in 92(64%) patients and was not effective in 52(36%) patients.
Conclusion: The accelerated SK infusion regimen of 1.5 MU in 20 min is safe and well tolerated with significantly faster and higher clinical reperfusion rates, more preserved LV systolic function, less atrial and ventricular sustained arrhythmias, and less in-hospital and 1 year mortality rates in acute STEMI.
USE OF THE STERI-STRIPS IN ACHIEVING RADIAL ARTERIAL ACCESS HEMOSTASIS
Authors: Khan Kamran Ahmed 
Published: November 2022

Objectives: The compression duration of the radial artery remained a key concern after coronary angiography (CA) and interventions via trans-radial access (TRA). We evaluate the impact of application of steri-strips along with conventional pneumatic trans-radial (TR) band on duration of compression required for hemostasis after diagnostic CA.
Methodology: In this open labeled randomized clinical trial, total of 209 patients who underwent diagnostic CA were randomized in 1:1 ratio into TR band with steri-strips (treatment) and conventional TR band alone (control) for achieving hemostasis. All patients were followed for 1 month. The primary endpoint was the duration of application of TR band and secondary endpoints were radial artery occlusion (RAO) and major bleeding.
Results: 106 patients received steri-strip along with TR band and 103 patients received TR band alone. The median duration of application of TR band was 60 [IQR: 60-60] min in the treatment group and 250 [IQR: 240-360] min in the control group; p≤0.001. The major bleed requiring reapplication of TR band was 9.4% vs. 4.9%; p=0.364 and hematoma (type I only) was 7.5% vs. 9.7%, p=0.578 in the treatment and control group respectively. Radial artery was palpable in 95.3% vs. 85.4%; p=0.016 after 24 hours and 96.2% vs. 88.3%; p=0.0.032, at 1 month in the treatment and control arm respectively.
Conclusion: Use of steri-strips is helpful in significantly reducing the compression duration of TR band and improving the patency of radial artery after diagnostic angiography with no significant rise in hematoma or major bleeding complications. Keywords: Steri-strips, radial artery, pneumatic TR band, coronary angiography, radial artery patency, radial artery occlusion.
OUTCOMES AND FACTORS ASSOCIATED WITH DISCHARGE AGAINST MEDICAL ADVICE IN PATIENTS DIAGNOSED WITH ACUTE CORONARY SYNDROME IN A SOUTH ASIAN COUNTRY
Authors: Ihsanullah Ihsanullah , Saeed Yawer , Ahmed Syed Waqar , Ali Jamshid , Hassan Mehdi , Rahman Nasir , Syed Harem , Inam Hina , Adnan Ghufran , Farhad Awais 
Published: November 2022

Objectives: Discharge/Left Against Medical Advice (AMA) is associated with worse outcomes in terms of MACE. There are no descriptions of ACS patients who left AMA in our nation cohorts. The aims of this study is to determine MACE in patients signing DAMA/LAMA and quantifying factors associated with LAMA in ACS patients in our population.
Methodology: An Ambi directional cohort study conducted on a total of n=257 patients from Jan 2014 to Dec 2018 who left AMA from a tertiary care hospital. Background data was collected from hospital electronic database and then patients/attendants were contacted through telephonic calls and email for follow up. Primary and secondary end points were to determine MACE and quantify factors associated with discharge AMA respectively.
Results: A total of n=346 patients signed discharge AMA from Jan 2014 to Dec 2018 out of which n=257 were successfully contacted and shared data after informed verbal consents. Out of 257, 63%(n=163) were men and 36.57%(n=94) were female. Hypertension was the common risk factor in both genders 80%(n=205) followed by DM and family history of premature coronary artery disease. Most common mode of presentation was NSTEMI followed by unstable angina and STEMI. Most common reason of LAMA was financial constraints in 43.1%(n=111) followed by treatment preferences in another setup and code DNR (don’t resuscitate). 22.57% patients belonged to low socioeconomic status. Total mortality till date of follow up was 60.7% (n=156) with One-year mortality of 78.8% (n=123) and 1st week mortality after LAMA was 15.18% (n=39). About 35.40% (n=91) of patient left to home and had mortality of 41%(n=64) and 64.56% (n=166) left for another hospital and had mortality of 58.97% (n=92). Those who survived had prevalence of recurrent MI and heart failure of 76% and 49% respectively on follow up.
Conclusion: Discharge against medical advice in ACS patients is associated with higher mortality. We need to educate our patients/attendant regarding disease severity, need of timely interventions and prognosis to decrease frequency of discharge AMA and minimize mortality.
EFFECT OF PERCUTANEOUS TRANSVENOUS MITRAL COMMISUROTOMY (PTMC) ON RIGHT VENTRICULAR FUNCTION
Authors: Wahab Muhammad Abdul , Rahman Syed Kashif ur , Shafiq Umer 
Published: November 2022

Objectives: Rheumatic heart disease causes significant morbidity and mortality among the cardiovascular diseases. Mitral stenosis (MS) is the commonest of all rheumatic heart disease. MVR was the definitive treatment for symptomatic mitral stenosis. But after the introduction of percutaneous transvenous mitral valve commissurotomy (PTMC), it is emerged as a safe and effective procedure for the treatment of symptomatic mitral stenosis. To determine the pre and post changes in right ventricular function among patients subjected to percutaneous mitral valve commissurotomy for mitral stenosis.
Methodology: This Quasi experimental study was conducted in the Department of Cardiology Hayatabad Medical Complex Peshawar from April, 2021-Oct, 2021. TTE was performed at baseline and PTMC was done in all patients. After PTMC, all patients were kept in CCU for next 24 hours and another TTE was performed at 24th hour after PTMC for measuring changes in the RV function in terms of RVSP, RVOT-FS, RV TEi index, RV wall thickness, pulmonary artery systolic pressure.
Results: As per changes in RV parameters before PTMC and 24 hours PTMC, mean and SDs for RVSAP was 5.70+4.50 with P Value 0.000. Mean and SDs for RVOT-FS was -1.22+3.02 with P Value 0.003. Mean and SDs for RV ETi index was 0.14+0.015 with P Value 0.000. Mean and SDs for RV wall thickness was 0.10+0.03 with P Value 0.000. Mean and SDs for pulmonary artery systolic pressure 17.099+4.20 with P Value 0.000.
Conclusion: PTMC has significant effect on pre and post changes in right ventricular function amongst patients subjected to percutaneous mitral valve commissurotomy for mitral stenosis.
COMPARATIVE ANALYSIS OF HEPATOTOXIC POTENTIAL OF SIMVASTATIN WITH ROSUVASTATIN AND REVERSAL VIA MONTELUKAST & COENZYME Q10 IN BALB/C MICE
Authors: Khan Manzoor , Jahan Sarwat , Ashraf Amber 
Published: November 2022

Objectives: Statins cause elevations of AST and ALT, cholestatic hepatotoxicity, fulminant hepatitis, autoimmune hepatitis, and cirrhosis. (2) Various mechanisms are hypothesized including reduced levels of Coenzyme Q10, inflammation and oxidative stress. Coenzyme Q10 is anti-apoptotic and possess antioxidative potential whereas Montelukast can reduce the inflammation via inhibition of leukotrienepathway. Hence both these drugs may have a protective effect against statin induced hepatotoxicity. This study will include the comparison of hepatotoxic potential of simvastatin and rosuvastatin and assess the hepatoprotective efficacy of montelukast and coenzyme 10.
Methodology: An experimental study of 2 weeks was conducted in the department of Pharmacology on a sample of 35 mice, randomly divided into 7 groups of 5 mice each for 2 weeks. Group 1 was used as control. Group 2 received simvastatin 50mg/kg/day of simvastatin intraperitoneally (I/P). Group 3 received I/P 50mg/kg/day rosuvastatin. Group 4 received 50mg/kg/day I/P simvastatin+3mg/kg of Montelukast. Group 5 received 50mg/kg/day of rosuvastatin +3mg/kg of Montelukast. Group 6 received 50mg/kg/day of simvastatin+10mg/kg of coenzyme Q10. Group 7 received 50mg/kg/day of rosuvastatin+10mg/kg of coenzyme Q10 I/P.
Results: Both the statins showed hepatotoxicity, however Simvastatin showed higher liver function derangements. Montelukast did not reduce hepatotoxicity significantly. A slightly lower rise in liver parameters was however observed. Coenzyme Q10 did not show any protective potential against the statins, rather higher liver function derangements were observed.
Conclusion: Simvastatin is more hepatotoxic as compared to Rosuvastatin. Motelukast does have a slight protective effect but is not significant enough. Coenzyme Q10 was not only not protective but infact indicated a hepatotoxic rend either by itself or via potentiating of statin induced hepatotoxicity.
DIGITAL TWIN METHODOLOGY FOR OBJECTIVE CONTROL OF LIVESTOCK PRODUCTION TECHNOLOGY (THROUGH THE EXAMPLE OF PIG BREEDING)
Authors: SOLYANIK V. V. , SOLYANIK S. V. 
Published: November 2022

According to the materials of the article, the digital twin of objective control of the agricultural enterprise should be based on monitoring the enterprise’s current account, on accounting entries, on the analysis of waybills, etc. Moreover, objective control should be carried out in real time by persons concerned with the obligatory informing of all employees of the enterprise. The temporal equality of two technological periods is justified: suckling, completion of growing, fattening of young pigs and rearing of replacement gilts, their insemination and pregnancy. The regularity in the equality of the two technological periods is the basis for the implementation of self-developing type-related technology (ST-technology), one of the elements of which is
the exclusion of the group of main sows from the production cycle and the transfer for slaughter of the first-litter sows, from which suckling piglets are weaned.
THE INFLUENCE OF VARIOUS FACTORS ON MILK PRODUCTIVITY IN THE AGRICULTURAL PRODUCTION BRANCH (APB) “ZAOZERIE” OF JSC “VITEBSK MEAT PROCESSING PLANT”
Authors: FURS N. L. , SINTSEROVA A. M. , MEDVEDEVA K. L. 
Published: November 2022

Various factors influence the milk productivity of cows. The article presents the results of studies conducted in the APB “Zaozerie” of JSC “Vitebsk Meat Processing Plant” on 326 cows with completed lactation. In the course of scientific and economic
experiment, it was found that the highest milk yield of 8417 kg was obtained from the cows of the 3rd lactation, with a significant increase in milk fat to the level of 316.4 kg. Gain in the live weight of cows in the herd to 651-700 kg contributes to a significant increase in their milk productivity to the level of 8430 kg of milk with a milk fat yield of 312.1 kg. The highest milk yield was obtained from cows with a dry period of 51-70 days - 9415 kg of milk (p≤0.001) with a milk fat yield of 358.7 kg and with a service period of 61-90 days - 7675 kg of milk with a milk fat yield of 285.5 kg (p≤0.001).
CALF REARING DURING THE PREWEANING PERIOD USING DIFFERENT FEEDING TECHNOLOGIES
Authors: RADCHIKOV V. F. , GLINKOVA A. M. , SALAEV B. K. , MARUSICH A. G. , SUDENKOVA Е. N. 
Published: November 2022

When raising young cattle, the aim is to minimize the consumption of whole milk, using a variety of milk substitutes to ensure normal growth and development of calves.
The purpose of the research, to which the article is devoted, was to develop the technology of feeding breeding heifers in the preweaning period, providing the normalization of metabolic processes in the body, as well as the improvement of feed use
efficiency. It has been established that feeding calves aged 10-65 days with the whole milk replacer according to the developed scheme has a positive effect on feed intake and enhances redox processes. It was also found that the average daily gain in live
weight of calves fed with whole milk was higher than that of counterparts consuming WMR by 3.7 % for the experiment. The cost of gain was almost the same.
Implementasi Pendidikan Moderasi Beragama Pondok Di Pesantren Kabupaten Sorong
Authors: Satir Muhammad , Rasyid Muhammad Rusdi , Rahmadana Arini 
Published: November 2022

The purpose of this study is to describe the phenomenon of implementation and implementation model of religious moderation education in Islamic boarding schools in Sorong Regency which has a pluralist, multiethnic and multicultural population. This is a descriptive-qualitative research with three Islamic boarding schools as research locations. Data were obtained from Kiayi, educators and students, using observation techniques, in-depth interviews, FGDs and documentation. The results of the study indicate that the process of implementing religious moderation education in the three Islamic boarding schools implemented automatically by the lessons of the students at the Islamic Boarding School. The implementation of religious moderation is reflected in several aspects, namely; national commitment through activities that contain the spirit of nationalism and respect for differences, understanding of tolerance and anti-radicalism obtained through the understanding of teachers and teaching materials; accommodative behavior towards local culture is reflected in the implementation of barzanji, yasinan, and tahlil. The implementation of moderation education is also accommodated through the integration of general formal education with Islamic boarding school diniyah education, then the teacher perspective through religious moderation and the most by the kitab kuning which contains a message of moderation through lessons on Aqidah, Sharia and Morals, especially in the kitab Aqidatul Awam, Akhlakul lil banin, Khulasoh and Risalah. Moderation model pattern in Islamic boarding schools in Sorong shows pattern, (1) The integration model of learning with Islamic material content that contains moderation values, especially through the teaching of The kitab kuning. The next pattern is (2) The collaboration model of Islamic boarding school curriculum with formal madrasas, dan the collaboration model of Islamic boarding school curriculum with local culture, and globalization.
Keywords:
Islamic Boarding School, Religious Moderation, The Kitab Kuning, Salafiyah-Modern
Peran Pendidikan Agama Islam Dalam Menanamkan Sikap Moderasi Beragama Siswa Di SMA Negeri 1 Rejang Lebong
Authors: Septian Rahmat Yudhi , Botifar Maria , Wanto Deri 
Published: November 2022

Abstract: SMA Negeri 1 Rejang Lebong is a school which incidentally is a superior public school located right in the heart of the capital city of Rejang Lebong district, of course there are various kinds of people with various ethnicities, customs and beliefs in this education unit. Starting from the indigenous students of Rejang and Lembak as well as descendants of Java, Sunda, Minang, Batak, Chinese, Serawai, and others are in this school. In terms of belief, teachers and students at SMA Negeri 1 Rejang Lebong also believe in the six official religions, namely Islam, Catholicism, Protestantism, Hinduism, Buddhism and Confucianism. Therefore, religious moderation is considered important and needs to be enforced in order to be able to guide the life of the school community in a good direction with a harmonious community structure without hatred and violence. In this journal article, the researcher uses field research with a descriptive qualitative approach with the principal and PAI teacher at SMA Negeri 1 Rejang Lebong as informants in this study. Then structured interview is the technique used in this study and data collection, data display, data reduction and verification or conclusion are data analysis techniques used in this study. SMA Negeri 1 Rejang Lebong has internalized the values ​​of religious moderation in Islamic religious education subjects and integrated them in the development of PAI materials and materials recorded in the PAI learning plan and their implementation has been realized in the PAI learning process.
Tercer aniversario de los mártires de la UCA ; Acuerdo de paz ; Los partidos políticos ; Problemática laboral ; Derechos humanos ; Centroamérica
Authors: El Editor  
Published: November 2022

No hay resúmenes disponibles.
ECA Estudios Centroamericanos, Vol. 47, No. 529-530, 1992: 1085-1107.
Libertad sindical, tratados internacionales y constitución
Authors: Huertas Tebelia 
Published: November 2022

Reflexión de carácter jurídico, en torno al papel de la constitución en el Estado de derecho que pretende ser el Estado salvadoreño, de su interpretación y de su relación con las leyes secundarias, en el caso de la asunción por el ordenamiento jurídico interno del derecho a la libertad sindical, en los términos establecidos en el derecho internacional público del trabajo. En la medida en que los argumentos en contra de la ratificación de estos convenios se han basado en su pretendida inconstitucionalidad, es necesario reflexionar sobre el papel de la constitución y los valores superiores que encarna, como ordenadores de todo el sistema jurídico.
ECA Estudios Centroamericanos, Vol. 48, No. 537-538, 1993: 657-675.
comisión de la verdad y el proceso electoral en la opinión pública salvadoreña
Authors: IUDOP  
Published: November 2022

A finales de junio de 1993 se pasó una encuesta de opinión pública entre una muestra de 1175 adultos, representativa de la población total de El Salvador, con un margen de error del 4 por ciento. Los resultados de la encuesta se refieren a dos grandes temas: la Comisión de la verdad y el proceso electoral. Por un lado, la mayoría de los salvadoreños está satisfecha con el informe de la Comisión de la verdad, adversa la amnistía decretada por el gobierno y pide la destitución de los funcionarios acusados de violar los derechos humanos. Por otro lado, la encuesta mostró que existe un alto porcentaje de personas que no sabe por quién votará en las próximas elecciones, aunque entre los definidos destaca ARENA, seguido a distancia por el PDC y la coalición FMLN-Convergencia.
ECA Estudios Centroamericanos, Vol. 48, No. 537-538, 1993: 711-734.
Body Mass Index as a Measure of Obesity and Cut-Off for Surgical Eligibility
Authors: Khangura Sara D. , Severn Melissa 
Published: November 2022

This report sought to identify, list, and annotate sources that reported findings regarding the accuracy and/or validity of body mass index as a measure of obesity or a cut-off for surgical eligibility, including reported ethical issues.
A limited literature search was conducted, and 35 eligible sources were selected and annotated.
Most studies with relevant findings regarding validity and/or accuracy reported discrepancies between body mass index and other measurements of obesity, or highlighted concerns with current practices that limit surgical eligibility by body mass index for patients who may derive benefit that exceeds the risk of complications.
Ethical issues reported included stigma, bias (particularly for racialized people), and the potential for body mass index and its use as a cut-off to create or exacerbate disparities in health care access.
The guidelines identified made recommendations for the use of body mass index cut-off(s) for surgical eligibility, generally intended to limit the risk of post-surgical complications.
Given the widespread use of body mass index as a measure of obesity and eligibility cut-off for surgical interventions, despite reported discrepancies in accuracy and validity, as well as ethical concerns, further consideration regarding its use is warranted.
Social Entrepreneurship sebagai Upaya Peningkatan Kesejahteraan Masyarakat
Authors: Hidayah Retnoningrum , Suryandari Dhini , Suryarini Trisni , Sukirman Sukirman , Rohmah Fian Tri 
Published: November 2022

Entrepreneurship menjadi hal yang penting bagi masyarakat di masa ini. Terutama bagi para wanita ibu rumah tangga yang membutuhkan tambahan pendapatan demi keberlangsungan ekonomi keluarganya Sistem kewirausahaan yang ramah lingkungan sosial menjadi solusinya. Oleh karena itu tim pengabdian bermaksud melaksanakan social entrepereneurship manik-manik bagi ibu rumah tangga di wilayah Kelurahan Sukorejo Kecamatan Gunungpati khususnya Dawis Bougenvile 1 RT 7 RW 5. Metode yang digunakan adalah pelatihan dan pendampingan ketrampilan pembuatan manik-manik. Pelatihan dilaksanakan secara luring dengan protokol kesehatan ketat. Hasil kegiatan sangat memuaskan. Hal ini terlihat dari peningkatan kemampuan para ibu rumah tangga dalam membuat konektor manik-manik. Pihak mitra pun telah menampung hasil kerajinan para wanita dan memberikan imbal jasa yang sesuai. Untuk selanjutnya, diharapkan kegiatan social entrepreneurship ini dapat berkesinambungan dan semakin banyak mitra yang bersedia menampung hasil karya masyarakat.
Upaya Peningkatan Pengetahuan Melalui Edukasi Penatalaksanaan Emergensi Pada Kejang Demam
Authors: Cing Marta Tania Gabriel Ching , Annisa Rully , Sulistyowati Retno 
Published: November 2022

Kejang demam atau penyakit step adalah kejang pada anak yang dipicu oleh demam, bukan diakibatkan kelainan di otak. Kejang demam biasanya terjadi pada anak usia 6 bulan hingga 5 tahun. Kondisi anak demam sudah menjadi masalah yang mampu membuat orang tua tau pengasuh panic. Pada survey yang dilakukan pada anggota mitra mengenai penanganan kejang demam pada anak dapat ditemukan bahwa pengetahuan anggota mitra tentang pertolongan pertama pada kejang demam masih rendah untuk itu perlu dilakukan upaya untuk meningkatakan tentang penanganan kejang demam yang terjadi dirumah dapat ditangani dengan benar dan menurunkan resiko untuk menjadi lebih berat. kegiatan ini dirancang dengan tehnik diskusi dan demonstrasi dalam menatalaksana kejang demam. hasil pretest pada kegiatan ini mendapatkan nilai skor rerata 60, setelah kegiatan nilai skor pada post test adalah 80 artinya terdapat peningkatan pengetahuan sebesar 33% dari nilai awal, berdasarkan hasil tersebut, dapat disimpulkan bahwa kegiatan ini dapat meningkatkan pengetahuan tentang penatalaksanaan kejang demam pada kondisi emergensi terutama di lingkungan rumah tangga.