bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bromide Dose in Dogs With Epilepsy Living Close to Coastal Areas and Living More Inland: A Retrospective Observational Study
Authors: Lichtenauer Esther A. , Evers Bas , van den Broek Jan , Mandigers Paul J. J. 
Published: May 2022

Potassium bromide is a frequently used antiseizure medication with a half-life time of over 25 days. Oral intake of sodium chloride as well as renal function influence this half-life time and may have an influence on the needed dose toget proper serumlevels. The hypothesis is that dogs living close to coastal areas require a greater potassium bromide dose than dogs living more inland. The main study objective was to determine the relationship between bromide dose, serum bromide concentration, treatment duration, type of food, concurrent therapies and the proximity of the dog's residency to a coastal area. A retrospective cross-sectional study was performed. A total of 658 bromide serum measurements were retrieved from the veterinary faculty's laboratory archive, Utrecht University, The Netherlands. Information on the bromide dose, renal function, treatment period, type of food, concurrent therapies and residence was obtained retrospectively from owners of all dogs using a postal survey. A dataset of 220 unique study units was created. The dogs were grouped based on their residence (proximity to the coast &gt; or &lt;50 km). Differences between the groups of dogs regarding bromide dose, serum bromide concentration, treatment duration, type of food and concurrent therapies were analyzed to evaluate the effect of residence on bromide dose and serum concentration.ResultsAlthough not statistically significant there is a trend that dogs living in close proximity to the sea may require a higher dose of potassium bromide to maintain therapeutic concentrations compared to dogs living more inlands. Additional studies are needed to further explore this observation.
Pandemic Fatigue and Anxiety Sensitivity as Associated Factors With Posttraumatic Stress Symptoms Among University Students in South Korea During the Prolonged COVID-19 Pandemic
Authors: Kim Hee Jun , Meeker Timothy J. , Tulloch Ingrid K. , Mullins Jake , Park Jin-Hee , Bae Sun Hyoung 
Published: May 2022

Objectives: The global impact of COVID-19 driven by new variants may add to the negative mental health consequences of the prolonged pandemic, including posttraumatic stress symptoms (PTSS). University students may be prone to develop a series of PTSS due to life plan disruptions as well as increased uncertainty caused by the pandemic. The purpose of this study was to assess the associations between pandemic fatigue, anxiety sensitivity (AS), and PTSS among university students in South Korea.Methods: Using convenience sampling, 400 students participated in this cross-sectional online survey. Descriptive statistics and linear mixed models were used to examine factors associated with PTSS.Results: About one-third (32.3%) of the participants reported clinically significant levels of PTSS. Multivariate analyses revealed that pandemic fatigue (β = 0.124, p &lt; 0.001) and AS (β = 0.212, p &lt; 0.001) were significantly associated with PTSS while controlling for other study variables.Conclusion: Young adults who feel more fatigue related to the COVID-19 pandemic and with high AS should be given access to mental health resources to better manage their mental health and reduce PTSS.
KECEMASAN PERAWAT MASA PANDEMI COVID 19: TINJAUAN LITERATURE
Authors: Rahmini Juwi Athia , - Widyawati 
Published: May 2022

The anxiety experienced by nurses during the COVID-19 pandemic is a feeling that cannot be avoided and affects the performance of nurses in providing nursing care. The purpose of article aims to describe nurses' anxiety during the COVID-19 pandemic. The method used is Narrative literature review by searching articles from Google Scholar dan DOAJ database with keyword nurse anxiety in COVID-19. The result of those articles are nurses experienced anxiety in providing nursing care during the COVID-19 pandemic. This anxiety is associated with age, female gender, experience, inadequate availability of personal protective equipment, lack of training on preparedness to face the COVID-19 pandemic outbreak. Nurses experience anxiety in carrying out nursing care during the COVID-19 pandemic. The government within hospital policies can anticipate intervening psychologically for nurses during a pandemic, such as providing consulting services, the availability of adequate personal protective equipment, and training for preparedness to face the COVID-19 pandemic effectively.
HYDROCRACKING COMPLEX - THE MAIN FACILITYOF THE FIRST STAGE OF AFIP REFINERY MODERNIZATION
Authors: Сидоров А. В. , Ясьян Ю. П. 
Published: May 2022

В данной работе проведен как анализ современных установок гидрокрекинга, так и выбор направления первого этапа модернизации Афипского НПЗ. Проведены технологические расчеты с учетом добавления в поточную схему завода установки гидрокрекинга, стабилизации бензиновой фракции, установки производства серы и установки производства водорода. Внедрение в схему завода нового комплекса гидрокрекинга существенно изменит производственные возможности по глубокой переработке нефти и по выпуску товарной продукции. В статье приводится математический расчет материального баланса, выполнена оценка расходных показателей энергоресурсов.
In this paper, both the analysis of modern hydrocracking units and the choice of the direction of the first stage of the modernization of the Afipsky refinery are carried out. Technological calculations were carried out taking into account the addition of a hydrocracking unit, stabilization of the gasoline fraction, a sulfur production unit and a hydrogen production unit to the flow scheme of the plant. The introduction of a new hydrocracking complex into the scheme of the plant will significantly change the production capabilities for deep oil refining and for the production of marketable products. The article provides a mathematical calculation of the material balance, an assessment of the consumption indicators of energy resources is made.
5G MOBILE NETWORK WIRELESS VIRTUALIZATION
Authors: Хаджиева Л. К. , Чадаева А. Б. 
Published: May 2022

Рост мобильных данных настолько значителен, что различные ресурсы, связанные с мобильной сетью, нуждаются в более эффективных механизмах управления и совместного использования. Технология виртуализации беспроводной сети представляет собой эффективный метод распределения и совместного использования ресурсов, введенный и пересмотренный в соответствующих спецификациях мобильной сети пятого поколения. В этой статье представлены основные концепции и технологии виртуализации беспроводных сетей, рассмотрены различные инновации и достижения НИОКР, основанные на технологии виртуализации беспроводной сети, и берем реальную проблему виртуализации ресурсов беспроводной сети и распределения ресурсов в качестве примера, чтобы дополнительно проанализировать, как исследователи изучают и решают эту проблему. Также в данной статье представлена идея оптимизации схемы BL, которую мы предлагаем на основе технологии сегментации требований к ресурсам и агрегации несущих.
The growth of mobile data is so significant that the various resources associated with the mobile network need better management and sharing mechanisms. Wireless network virtualization technology is an efficient resource allocation and sharing method introduced and revised in the related fifth generation mobile network specifications. This article introduces the main concepts and technologies of wireless network virtualization, discusses various innovations and R&D achievements based on wireless network virtualization technology, and takes the real problem of wireless network resource virtualization and resource allocation as an example, to further analyze how researchers study and solve this problem. This article also presents the idea of optimizing the BL scheme, which we propose based on the technology of segmentation of resource requirements and carrier aggregation.
INFLUENCE OF BITUMEN COMPOSITION ON PERFORMANCE PROPERTIES
Authors: Тарамов Ю. Х. , Цамаева П. С. , Эльмурзаев А. А. 
Published: May 2022

Битумы являются одним из продуктов нефтепереработки. На свойства битумов влияет сам источник нефти и технологический процесс переработки нефти. Большинство европейских нефтеперерабатывающих заводов, конечно же, занимаются переработкой с целью перепродажи нефтепродуктов, особенно нефти, пригодной для извлечения легких и средних фракций. Поэтому необходимы легкие нефти с низкими выходами тяжелых фракций, которые высокоэкономичны и выгодны для переработчиков на нефтяном рынке. С точки зрения нефтепереработки содержание и соотношение асфальтенов и мальтенов, как обязательных компонентов битума, становится менее важным, однако это может существенно повлиять на будущие свойства битумного вяжущего. Основные тесты на температуру проникновения и размягчения предназначены для оценки свойств битума и классификации битума. Этих испытаний в настоящее время недостаточно, и поэтому разрабатываются новые методы и процедуры испытаний для определения характеристик битума. Основной темой подхода к оценке свойств битумных вяжущих, основанного на характеристиках, является оценка свойств с точки зрения характеристик дорожной одежды, таких как остаточная деформация, усталость и морозное растрескивание. Также важна оценка изменения свойств битума в процессе производства и укладки асфальтобетонной смеси. Исследование направлено на изучение вязкостно-температурного поведения и фундаментальных свойств, представленных пенетрацией и температурой размягчения образцов дорожного покрытия.
Bitumen is one of the products of oil refining. The properties of bitumen are affected by the source of oil itself and the technological process of oil refining. Most European refineries, of course, are refining for the purpose of reselling petroleum products, especially oil suitable for the recovery of light and medium fractions. Therefore, there is a need for light crudes with low heavy ends yields that are highly economical and beneficial to refiners in the oil market.From the point of view of oil refining, the content and ratio of asphaltenes and maltenes, as essential components of bitumen. becomes less important, but it can significantly affect the future properties of the bituminous binder. The basic penetration and softening temperature tests are designed to evaluate the properties of bitumen and classify bitumen. These tests are not currently sufficient and therefore new test methods and procedures are being developed to characterize bitumen. The main topic of the performance-based approach to assessing the properties of bituminous binders is the assessment of properties in terms of pavement characteristics such as set, fatigue and frost cracking. It is also important to assess the change in the properties of bitumen during the production and laying of the asphalt mix. The study is aimed at studying the viscosity-temperature behavior and fundamental properties represented by penetration and softening temperature of pavement samples.
Spin Peltier effect and its length scale in Pt/YIG system at high temperatures
Authors: Takahagi Atsushi , Hirai Takamasa , Iguchi Ryo , Nakagawara Keita , Nagano Hosei , Uchida Ken-ichi 
Published: May 2022

Abstract
The temperature and yttrium-iron-garnet (YIG) thickness dependences of the spin Peltier effect (SPE) have been investigated using a Pt/YIG junction system at temperatures ranging from room temperature to the Curie temperature of YIG by the lock-in thermography method. By analyzing the YIG thickness dependence using an exponential decay model, the characteristic length of SPE in YIG is estimated to be 0.9 μm near room temperature and almost constant even near the Curie temperature. The high-temperature behavior of SPE is clearly different from that of the spin Seebeck effect, providing a clue for microscopically understanding the reciprocal relation between them.
Comprometimento da Função Cognitiva em Idosos Devido Exposição À Material Particulado
Authors: Gavioli Aline , Santos Gabriela da Silva , Sant'ana Maria Helena Santos de , Alves Vanessa de Oliveira , Mota Rrtiz Sandra Regina 
Published: May 2022

O envelhecimento populacional traz consigo problemas de saúde que desafiam os sistemas de saúde e de previdência social. Envelhecer não significa necessariamente adoecer. A menos que exista doença associada, o envelhecimento está associado a um bom nível de saúde. Associações entre poluição do ar e efeitos adversos da saúde cardiopulmonar estão bem documentadas. Partículas ultrafinas (UFP; <100 nm de diâmetro), encontradas onipresentemente no ar em ambiente interno e externo, são consideradas o componente mais tóxico da poluição do ar ambiente. Evidências crescentes sugerem que os poluentes do ar também podem afetar adversamente o sistema nervoso central (SNC). Estudos epidemiológicos identificaram associações entre a exposição a diversos poluentes do ar ambiente, como material particulado (PM), ozônio, monóxido de carbono e dióxido de nitrogênio com eventos cerebrovasculares isquêmicos, com um dos primeiros estudos relatando aumento do risco de acidente vascular cerebral devido à exposição a vapores de carvão em ambientes fechados. À medida que a incidência da doença de Alzheimer (DA) e outras doenças neurodegenerativas aumentam, há um crescente interesse em fatores ambientais que podem contribuir para o início e a progressão da doença. A poluição do ar é conhecida como um grande risco à saúde há décadas. Embora seus efeitos sobre a morbimortalidade cardiopulmonar tenham sido extensivamente estudados, surgiram evidências crescentes de que a exposição ao ar poluído está associada a funções cognitivas prejudicadas em todas as idades e aumento do risco de DA e outras demências mais tarde na vida; essa associação é particularmente notável com poluentes relacionados ao tráfego.
Educação Física na Escola: Um Estudo de Caso Sobre Perspectiva Discente
Authors: Ferreira Jean Francisco dos Santos , Meireles Bruno Freitas , Filgueiras Isabel Porto 
Published: May 2022

O trabalho investigou a perspectiva dos alunos dos terceiros anos e quartas séries do Ensino Fundamental de uma escola pública sobre as aulas de Educação Física. Os objetivos foram: identificar os conhecimentos dos alunos sobre os conteúdos da cultura corporal de movimento e enumerar as preferências sobre os conteúdos trabalhados pela professora.. A amostra foi composta por 85 sujeitos, 41 crianças dos terceiros anos (17 meninas e 24 meninos) e 44 das quartas séries (26 meninas e 18 meninos), com idades entre oito e doze anos. A pesquisa caracteriza-se como pesquisa descritiva. Os instrumentos utilizados foram um questionário com perguntas abertas e fechadas e observação naturalística. Os resultados indicam que a maioria dos alunos conhece e vivenciou conteúdos da cultura corporal de movimento nos eixos de lutas, esportes, danças, ginásticas e brincadeiras, embora a professora não tenha trabalhado os eixos de lutas e esportes As atividades que as crianças não gostam ou gostam pouco e as que gostam ou gostam muito são bastante diversificadas, tantas diferenças indicam a heterogeneidade de interesses a qual os professores de Educação Física lidam cotidianamente. Percebem-se diferenças de interesses pelos conteúdos de aula em função do gênero dos alunos. A atividade de pular corda apresentou a maior diferença. Há mais meninos do que meninas que rejeitam essa atividade. As brincadeiras de pega-pega aparecem em primeiro lugar entre as atividades que os alunos não gostam ou gostam pouco, provavelmente porque são estratégias utilizadas desde o ensino infantil. O futebol aparece em segundo lugar frente as atividades rejeitadas pelos alunos de ambos os gêneros, mas há mais meninas do que meninos que não gostam dessa atividade. O futebol aparece tanto nas preferências como nos conteúdos que as crianças não gostam ou gostam pouco. Esse parece ser um conteúdo que divide opiniões. As aulas na piscina forma as preferidas dos alunos, seguidas das aulas com brincadeiras no parque, denotando um diferencial das aulas de Educação Física que podem ser desenvolvidas nos CEUs. O estudo permitiu observar que há grande diversidade de interesses das crianças nas atividades das aulas de Educação Física e que os alunos conhecem todos os conteúdos da cultura corporal de movimento independentemente de serem trabalhados na escola. Os alunos gostariam de vivenciar mais atividades de lutas e esportes coletivos, além do Skate, atividades presentes na estrutura do CEU, mas que não foram abordadas pela professora da Escola.
Níveis De Expressão Gênica Das Semaforinas 3A E 4D No Reparo Ósseo Alveolar De Ratos Normo E Hiperglicemicos
Authors: Redondo Gabriela Maria , Malta Fernando Souza , Silva Vanessa Sousa da , Bastos Marta Ferreira 
Published: May 2022

O diabetes mellitus é uma desordem metabólica de múltipla etiologia caracterizada pela hiperglicemia crônica com distúrbios no metabolismo que podem afetar de modo negativo a cicatrização e o reparo tecidual. Diversas vias de sinalização desempenham um papel essencial na manutenção da integridade do esqueleto pela regulação positiva ou negativa das células ósseas. As semaforinas constituem uma família de proteínas ligadas a superfície celular ou secretadas que são capazes de regular a interação, morfologia e função de diferentes tipos de células. A Semaforina 3A (Sem3A) tem sido envolvida em atividades de remodelamento ósseo, e também são encontrados relatos sobre a atividade da Semaforina 4D (Sem4D) durante a reabsorção óssea realizada pelos osteoclastos. O objetivo do presente estudo foi avaliar o nível de expressão das Semaforinas 3A e 4D do tecido ósseo alveolar neoformado de ratos normo e hiperglicêmicos. Os animais foram divididos nos seguintes grupos: Não Hiperglicemicos (NH, n=10) e hiperglicêmicos (H, n=10). A hiperglicemia foi induzida nos animais pela administração de água com 10% de frutose e estreptozotocina no 14º dia após. No 76º dia após indução da hiperglicemia, todos os animais foram anestesiados e submetidos a uma exodontia para remoção dos molares inferiores. No 84º dia aconteceu à eutanásia, em seguida foi realizada uma curetagem do tecido ósseo neoformado que foi armazenado em RNA later® para extração do RNA total, tratamento com DNAse e preparo do cDNA e análise da expressão gênica de Sem3A e Sem4D. Os resultados foram submetidos a teste de normalidade e foram selecionados teste não paramétrico com nível de significância estabelecido em 5% (p <0,05). Os resultados do presente estudo sugerem que no modelo experimental utilizado, os níveis de expressão gênica de Sema 3A e 4D não estão associados ao impacto negativo da hiperglicemia sobre o reparo ósseo.
Novel one-pot synthesis of 2-thio-substituted-3-H-phenothiazin-3-ones driven by oxidation with sodium periodate
Authors: Odens Jr. Herman H , You Jae Y , Gallimore Alexandria D , Palm Preston H , Davis Cameron W , Bahena Josue M , Moser Jeffrey S , Smith Mackenzie E , Odens Herman H 
Published: May 2022

A series of novel 2-thio-substituted-3H-phenothiazin-3-ones (6h-l) was effectively synthesized in one pot after optimization of the four-step synthesis. Treatment of a 2-alkylthio-1,4-benzoquinone (3a-l) made in situ and condensed with 1,2-aminothiophenol (5) followed by oxidation with NaIO4 produced the desired final targets. A four-step reaction sequence in which 1,4-benzoquinone (1) is first reacted with an alkylthiol (2a-l) in the presence of sodium periodate (NaIO4) and then treated with 2-aminothiophenol (5) followed by a second oxidation with sodium periodate was demonstrated to be effective in synthesizing 2-thio-substituted-3H-phenothiazin-3-ones (6a-g). The one-pot synthesis is an improvement of the stepwise synthesis of these 2-thio-substituted-3H-phenothiazin-3-one heterocycles since four steps are run in sequence and treated as one.
Multi-instrument Comparative Study of Temperature, Number Density, and Emission Measure during the Precursor Phase of a Solar Flare
Authors: Liu Nian , Jing Ju , Xu Yan , Wang Haimin 
Published: May 2022

Abstract
We present a multi-instrument study of the two precursor brightenings prior to the M6.5 flare (SOL2015-06-22T18:23) in the NOAA Active Region 12371, with a focus on the temperature (T), electron number density (n), and emission measure (EM). The data used in this study were obtained from four instruments with a variety of wavelengths, i.e., the Solar Dynamics Observatory’s Atmospheric Imaging Assembly (AIA), in six extreme ultraviolet (EUV) passbands; the Expanded Owens Valley Solar Array (EOVSA) in microwave (MW); the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) in hard X-rays (HXR); and the Geostationary Operational Environmental Satellite (GOES) in soft X-rays (SXR). We compare the temporal variations of T, n, and EM derived from the different data sets. Here are the key results. (1) GOES SXR and AIA EUV have almost identical EM variations (1.5–3 × 1048 cm−3) and very similar T variations, from 8 to 15 million Kelvin (MK). (2) Listed from highest to lowest, EOVSA MW provides the highest temperature variations (15–60 MK), followed by RHESSI HXR (10–24 MK), then GOES SXR and AIA EUV (8–15 MK). (3) The EM variation from the RHESSI HXR measurements is always less than the values from AIA EUV and GOES SXR by at most 20 times. The number density variation from EOVSA MW is greater than the value from AIA EUV by at most 100 times. The results quantitatively describe the differences in the thermal parameters at the precursor phase, as measured by different instruments operating at different wavelength regimes and for different emission mechanisms.
The Eel Pulsar Wind Nebula: A PeVatron-candidate Origin for HAWC J1826−128 and HESS J1826−130
Authors: Burgess Daniel A. , Mori Kaya , Gelfand Joseph D. , Hailey Charles J. , Tokayer Yarone M. , Woo Jooyun , An Hongjun , Malone Kelly , Reynolds Stephen P. , Safi-Harb Samar , Temim Tea 
Published: May 2022

Abstract
HAWC J1826−128 is one of the brightest Galactic TeV γ-ray sources detected by the High Altitude Water Cherenkov (HAWC) observatory, with photon energies extending up to nearly ∼100 TeV. This HAWC source spatially coincides with the H.E.S.S. TeV source HESS J1826−130 and the “Eel” pulsar wind nebula (PWN), which is associated with the GeV pulsar PSR J1826−1256. In the X-ray band, Chandra and XMM-Newton revealed that the Eel PWN is composed of both a compact nebula (∼15″) and diffuse X-ray emission (∼6′ × 2′) extending away from the pulsar. Our NuSTAR observation detected hard X-ray emission from the compact PWN up to ∼20 keV and evidence of the synchrotron burn-off effect. In addition to the spatial coincidence between HESS J1826−130 and the diffuse X-ray PWN, our multiwavelength spectral energy distribution (SED) analysis using X-ray and γ-ray data establishes a leptonic origin of the TeV emission associated with the Eel PWN. Furthermore, our evolutionary PWN SED model suggests (1) a low PWN B-field of ∼1 μG, (2) a significantly younger pulsar age (t ∼ 5.7 kyr) than the characteristic age (τ = 14.4 kyr), and (3) a maximum electron energy of

E

max

=
2

PeV. The low B-field, as well as the putative supersonic motion of the pulsar, may account for the asymmetric morphology of the diffuse X-ray emission. Our results suggest that the Eel PWN may be a leptonic PeVatron particle accelerator powered by the ∼6 kyr old pulsar PSR J1826−1256 with a spin-down power of 3.6 × 1036 erg s−1.