bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultralow voltage, high-speed, and energy-efficient cryogenic electro-optic modulator
Authors: Pintus Paolo , Singh Anshuman , Xie Weiqiang , Ranzani Leonardo , Gustafsson Martin V. , Tran Minh A. , Xiang Chao , Peters Jonathan , Bowers John E. , Soltani Moe 
Published: September 2022

Photonic integrated circuits (PICs) at cryogenic temperatures enable a
wide range of applications in scalable classical and quantum systems
for computing and sensing. A promising application of cryogenic PICs
is to provide optical interconnects by upconverting signals from the
electrical to the optical domain, allowing a massive data transfer
from 4 K superconducting (SC) electronics to the room temperature
environment. Such a solution can overcome a major bottleneck in the
scalability of cryogenic systems that currently rely on bulky coaxial
cables that suffer from limited bandwidth, a large heat load, and poor
scalability. A key element to realize a cryogenic-to-room temperature
optical interconnect is a high-speed, electro-optic (EO) modulator
operating at 4 K with a modulation voltage at the mV scale, compatible
with SC electronics. Although several cryogenic EO modulators have
been demonstrated, their driving voltages are substantially large
(several hundred mV to a few V) compared to the mV scale voltage
provided by SC circuits. Here, we demonstrate a cryogenic modulator
with

∼

10

m
V

peak-to-peak driving voltage and Gb/s
data rate, with an ultralow electric energy consumption of

∼

10.4

a
J

/

b
i
t

and an optical energy consumption of

∼

213

f
J

/

b
i
t

. We achieve this record performance
by designing and fabricating a compact optical ring resonator
modulator in a heterogeneous InP-on-Si platform, where we optimize a
multi-quantum-well layer of InAIGaAs to achieve a strong EO effect at
4 K. Unlike other semiconductors such as silicon, our platform
benefits from the high-carrier mobility and minimal free-carrier
freezing of III-V compounds at low temperatures, with a moderate
doping level and a correspondingly low loss (intrinsic resonator

Q

∼

272

,

000

). These modulators can pave the path
for complex cryogenic photonic functionalities and massive data
transmission between cryogenic and room-temperature electronics.
Breaking the bandwidth limit of a high-quality-factor ring modulator based on thin-film lithium niobate
Authors: Xue Yu , Gan Ranfeng , Chen Kaixuan , Chen Gengxin , Ruan Ziliang , Zhang Junwei , Liu Jie , Dai Daoxin , Guo Changjian , Liu Liu 
Published: September 2022

Growing global data traffic requires high-performance modulators with a compact size, a large bandwidth, a low optical loss, and a small power consumption. A careful trade-off among these parameters usually has to be made when designing such a device. Here, we propose and demonstrate an electro-optic ring modulator on the thin-film lithium niobate platform without compromising between any performances. The device exhibits a low on-chip loss of about 0.15 dB with a high intrinsic quality-factor (Q-factor) of

7.7

×

10

5

. Since a pure coupling modulation is employed, the photon lifetime is no longer a limiting factor for the modulation speed. A large electro-optic bandwidth is obtained without any roll-off up to 67 GHz. The device, with a footprint of

3.4

m
m

×

0.7

m
m

, also exhibits a low half-wave voltage of 1.75 V, corresponding to a half-wave voltage length product of

0.35

V

⋅

c
m

considering the 2-mm-long modulation section. Driverless data transmission up to 240 Gb/s is also demonstrated with a peak-to-peak driving voltage of 0.75 V.
Recurrence pattern predicts aneurysm rupture after coil embolization
Authors: Nambu Iku , Misaki Kouichi , Uno Takehiro , Yoshikawa Akifumi , Uchiyama Naoyuki , Mohri Masanao , Nakada Mitsutoshi 
Published: September 2022

Introduction
Hemorrhage from a recurrent aneurysm is a major concern after coiling for intracranial aneurysms. We aimed to identify aneurysm recurrence patterns associated with hemorrhage.

Material and methods
We investigated radiological data of patients who underwent coiling for intracranial aneurysms in 2008–2016 and were followed-up for at least 6 months. Aneurysm recurrence patterns were classified as: type Ⅰ, enlargement of aneurysm neck; type Ⅱ, recurrent cavity within the coil mass; type Ⅲ, recurrent cavity along the aneurysm wall; and type Ⅳ, formation of a daughter sac. We evaluated the incidence of various recurrence patterns with or without hemorrhage.

Results
Of the 173 aneurysms included in the study (mean follow-up period, 32 months; range, 6–99 months), 22 (13%) recurred and required re-treatment. The recurrence patterns included type Ⅰ, Ⅱ, Ⅲ, and Ⅳ in 7 (4%), 4 (2%), 9 (5%), and 2 (1%) cases, respectively. Most of the type Ⅰ, Ⅱ, and Ⅲ recurrences occurred within 1 year, and type Ⅳ occurred at 7 years after coiling. Three aneurysms exhibited hemorrhage, one with type Ⅲ and two with type Ⅳ pattern. The two aneurysms with type Ⅳ recurrence initially occurred as type Ⅰ; however, the recurrent neck enlarged gradually, resulting in new sac formation.

Conclusions
We recommend prompt re-treatment for aneurysms recurring with type Ⅲ or Ⅳ patterns, as such patterns were associated with hemorrhage. Furthermore, we need a special care to type Ⅰ recurrence with enlargement of recurrent neck because this specific pattern may develop to type Ⅳ.
Detection of cutaneous malignant melanoma using RNA sampled by tape strips: A study protocol
Authors: Heerfordt Ida M. , Andersen Jeppe D. , Philipsen Peter A. , Langhans Linnea , Tvedebrink Torben , Schmidt Grethe , Poulsen Thomas , Lerche Catharina M. , Morling Niels , Wulf Hans Christian 
Published: September 2022

Background
Cutaneous malignant melanoma (CMM) is curable if detected in its early stages. However, the clinical recognition of CMM is challenging. An American research group has shown promising results in detecting CMM based on RNA profiles sampled from suspicious lesions with tape strips. We aim to further develop this technique and validate if RNA profiles sampled with tape strips can detect CMM.

Methods
This prospective cohort study will include approximately 200 lesions clinically suspected of CMM requiring surgical removal. Tape stripping of the lesions will be performed just before surgical excision. Subsequently, RNA on the tape strips is analyzed using quantitative real-time polymerase chain reaction with TaqMan technology. The results are combined into a binary outcome where positive indicates CMM and negative indicates no CMM. The histopathological diagnosis of the lesions will be used as the gold standard. The main outcome is the results of the RNA test and the histopathological diagnosis, which, combined, provide the sensitivity and specificity of the test.

Discussion
The accuracy of the clinical examination in CMM diagnostics is limited. This clinical trial will explore the ability to use RNA analysis to improve the management of suspicious lesions by enhancing early diagnostic accuracy. Hopefully, it can reduce the number of benign lesions being surgically removed to rule out CMM and decrease patient morbidity.

Trial registration
The project was approved by The Committee on Health Research Ethics of the Capital Region of Denmark (H-15010559) and registered at the Danish Data Protection Agency (BFH-2015-065).
Epidemiology and risk factors related to severity of clinical manifestations of COVID-19 in outpatients: A retrospective study in Haiti
Authors: Lucien Mentor Ali Ber , Pierre Katilla , Jean-Denis Gladzdin , Rigodon Jonas , Worrell Caitlin M. , Couture Alexia , Flynn Aspen , Calderon Mauricio Cerpa , Codina Luis Felipe , Vicari Andrea S. , Marseille Samson , Jean Baptiste Koama T. , Fouche Bernadette , Joseph Gerard , Journel Ito , Rendel Kenold , Grant-Greene Yoran , Jean-Charles Nadia P. , Lafontant Donald , Amouzou Senou , Pierre Wilnique , Clement Marie Greta Roy , Juin Stanley , Boncy Jacques , Dely Patrick 
Published: September 2022

Background
Haiti’s first COVID-19 cases were confirmed on March 18, 2020, and subsequently spread throughout the country. The objective of this study was to describe clinical manifestations of COVID-19 in Haitian outpatients and to identify risk factors for severity of clinical manifestations.

Methods
We conducted a retrospective study of COVID-19 outpatients diagnosed from March 18-August 4, 2020, using demographic, epidemiological, and clinical data reported to the Ministry of Health (MoH). We used univariate and multivariate analysis, including multivariable logistic regression, to explore the risk factors and specific symptoms related to persons with symptomatic COVID-19 and the severity of symptomatic COVID-19 disease.

Results
Of 5,389 cases reported to MOH during the study period, 1,754 (32.5%) were asymptomatic. Amongst symptomatic persons 2,747 (75.6%) had mild COVID-19 and 888 (24.4%) had moderate-to-severe disease; the most common symptoms were fever (69.6%), cough (51.9%), and myalgia (45.8%). The odds of having moderate-to-severe disease were highest among persons with hypertension (aOR = 1.72, 95% Confidence Interval [CI] (1.34, 2.20), chronic pulmonary disease (aOR = 3.93, 95% CI (1.93, 8.17)) and tuberculosis (aOR = 3.44, 95% CI (1.35, 9.14)) compared to persons without those conditions. The odds of having moderate-to-severe disease increased with age but was also seen among children aged 0–4 years (OR: 1.73, 95% CI (0.93, 3.08)), when using 30–39 years old as the reference group. All of the older age groups, 50–64 years, 65–74 years, 75–84 years, and 85+ years, had significantly higher odds of having moderate-to-severe COVID-19 compared with ages 30–39 years. Diabetes was associated with elevated odds of moderate-to-severe disease in bivariate analysis (OR = 2.17, 95% CI (1.58,2.98) but, this association did not hold in multivariable analyses (aOR = 1.22,95%CI (0.86,1.72)).

Conclusion
These findings from a resource-constrained country highlight the importance of surveillance systems to track emerging infections and their risk factors. In addition to co-morbidities described elsewhere, tuberculosis was a risk factor for moderate-to-severe COVID-19 disease.
A Game-Theoretic Analysis of the Sanctions for Breach of Duty to Disclose in Insurance Contracts: A Comparison of the “All or Nothing” and “Pro Rata” Methods
Authors: Okura Mahito , Sakaki Motohiro , Yoshizawa Takuya 
Published: September 2022

AbstractUsing a game-theoretic analysis, this study aims to investigate which of the “all or nothing” and “pro rata” methods, regarding the sanction against the breach of duty to disclose in insurance contracts by negligence, is better from two perspectives: one is in terms of how much the sanction increases the policyholder’s probability of effort, while the other is how much it increases the probability of finding the wrong type of policyholder by insurance firms. From the analysis, we find that the desirable method depends on the probability that the policyholders can effortlessly determine their precise risk type as well as their effort cost level.
An improved intermittent power supply technique for electrostatic precipitators
Authors: Ganesamoorthy Rajkumar , Srinivasan Sekar 
Published: September 2022

Abstract
A cost-effective power supply design proposed for electrostatic precipitators (ESP) is presented in this work. The cost minimization is done in terms of eliminating the power transformer and reducing power consumed by the ESP unit. Usually, transformers are used to boost the voltage level in conventional systems on its input side, which is replaced by a combination of a high-frequency converter along with a voltage multiplier in a modular arrangement. By interconnecting these modules, the suitable voltage is built-up easily. An intermittent pulse energized supply is developed by the proposed system to reduce back corona and to save energy consumption. The modular arrangement also increases the lifetime of converter switches, by reducing the switching stresses developed across them during its high-frequency operation and by reducing the Total Harmonic Distortion (THD). The complete system is designed and analyzed using MATLAB SIMULINK. The obtained results are better than the existing methods used for generating intermittent energization, the THD is reduced to 35.78% and the voltage stresses also reduced to 1800 V. And a module is experimented and found that it is capable of producing 3 kV.
Is e-Government a Driver to Enhance Entrepreneurship? An Empirical Investigation of European Countries
Authors: Ha Le Thanh 
Published: September 2022

Abstract
This paper investigates the influences of digital public services on the ease of setting up a new business in 28 European countries during the period of 2012–2019. The development of digital public services is reflected in business mobility and key enablers. The digitalization-entrepreneurship nexus is analyzed by using the panel corrected standard error (PCSE) model, while we employ the dynamic fixed effects estimator (DFE) used in the autoregressive distributed lag (ARDL) model to measure the short-run and long-run effects. Our results indicate that the online delivery of government services positively affects the density of entrepreneurship in a country. We find robust results utilizing various econometric techniques and adding further explanatory variables. However, the positive effects of offering public services online are only found in the long run. Using digital public services benefits the entrepreneurial sectors by reducing the time and costs required to start a new business. Notably, digital transformation in the public sector acts as a shield to protect enterprises by dampening the detrimental effects of uncertainty on entrepreneurship.
Conscientiousness of environmental concepts in sustainable development and ecological conservation
Authors: Ganesan Subbulakshmi , Padmapriya Gopalakrishnan , Anupama De Zoysa Agampodi Sanduni 
Published: September 2022

Abstract
Environmental pollution is a major global threat that is faced by the humans. Environmental science can be applied in many ways to protect the earth by pollution, by using innovative methods which will lead to the sustainable development. Production of biodiesel, bioplastic, bio pesticides, biogas, and biofertilizers are few of the ways that can be used in order to reduce and prevent the pollution. All the above ideas which are involved with scientific methodologies are discussed here. Moreover, these can act as promising solutions for the exciting environmental problems.
Lessons learned – Moving on from QST sensory profiles
Authors: Schmelz Martin 
Published: September 2022

Abstract
Quantitative sensory testing (QST) has been optimized to diagnose in particular small fiber neuropathy and has been successfully used for decades. “Sensory phenotypes” have been derived from the QST data in an attempt to stratify patients with chronic pain and to gain mechanistic insights. However, studies consistently show that there is no difference in sensory phenotypes between neuropathy patients with and without pain and no successful stratification has been shown using the current version of “sensory phenotypes”. Thus, after falsification of the initial hypothesis it is time to focus on more promising approaches.
Sensory testing might not be perfect – but it is the best biomarker for pain phenotypes we have right now
Authors: Vollert Jan 
Published: September 2022

Abstract
Currently available treatments for neuropathic pain fail in roughly half of the patients – and it is impossible to predict which treatments will help patients. Stratification of neuropathic pain patients is needed, and sensory profiling has so far been the most promising approach: it has been shown to be responsive to treatment, linked to potential mechanisms, and, most importantly, predictive of treatment success. Despite a number of limitations, it is the currently most promising stratification tool and should be refined rather than disregarded.
Orthoamide und Iminiumsalze, CVIa. Kondensationsreaktionen von Orthoamiden der Alkincarbonsäuren mit CH-aciden Methylheterocyclen
Authors: Kantlehner Willi , Edelmann Kai , Vettel Markus 
Published: September 2022

Abstract
Orthoamides of alkynecarboxylic acids 10 react with 2-thienyl-acetonitrile under condensation to give ketene aminals. In the reaction of orthoamides 10 with 2-benzimidazolyl-acetonitrile tricyclo[1,2-a]benzimidazol-4-carbonitriles are formed under similar conditions. From 2-methyl-1,3-disubstituted-triazin-2,4-diones and orthoamides 10 the ketene aminals result at room temperature.
Microstructural Evolution of Inconel 718 during Aging and Its Correlation with Electric Conductivity Measurements
Authors: Mata-Rodríguez Marcos Ariel , García-Rentería Marco Arturo , Ambríz-Rojas Ricardo Rafael , Cabral-Miramontes José Ángel , López-Morelos Victor Hugo , Ramírez-López Maria del Carmen , Curiel-López Francisco Fernando 
Published: September 2022

Abstract
The microstructural evolution of the nickel-base superalloy Inconel 718 after exposition at 750°C for different holding times (10 min–1,000 h) was characterized and correlated with the Eddy current (EC) technique. The results showed that electrical conductivity increases with aging time. This behavior was associated with the precipitation and coarsening of the metastable γ″ phase and its transformation into the detrimental δ phase after 100 h. EC nondestructive evaluation was correlated with X-ray diffraction patterns in terms of the precipitation and growth of secondary carbides that were observed in the scanning electron microscope. Vickers microhardness values were also in agreement with microstructural changes and EC measurements, as the maximum hardened condition can be associated with the precipitation of secondary phases before the transformation of the γ″ phase into the δ phase.
Boron Nitride Nanotubes (BNNTs) and BNNT Composites: A Review
Authors: Tank Mehul , Sweat Rebekah 
Published: September 2022

Abstract
This paper provides a summary of recent advances in boron nitride nanotubes (BNNTs) and their composites, including properties, purification, characterization techniques involved, failure modes, and modeling methods. After the discovery of carbon nanotubes, BNNTs were first theoretically predicted and successfully synthesized in 1995 by an arc-discharge method. Following that, other techniques for BNNT synthesis were discovered; however, growing highly purified BNNTs remains difficult. The research on the physical properties of BNNTs shows that they have a stable broadband gap, excellent mechanical strength, high thermal conductivity, and high oxidation resistance. These properties make them a perfect candidate for future nanocomposites for high-temperature applications. Interesting effects of BNNT addition with the resultant mechanical behavior and thermal conductivity in a matrix are observed when BNNTs are applied to form nanocomposites with polymer, metal, and ceramic matrices. Modeling and simulation methods of nanotube composites are highly advantageous in developing BNNT-based nanocomposites. Micromechanics, finite element analysis, and molecular dynamics are modeling techniques used to simulate nanotubes and are crucial for model- informed manufacturing and design. In summary, modeling, synthesis, purification, characterization, and properties of BNNT composites are all reviewed in this paper.
Maternal Depressive Symptoms and Adolescents’ Unhealthy Behavior: A 15-year Longitudinal Study
Authors: Bechtiger Laura , Steinhoff Annekatrin , Dollar Jessica M. , Calkins Susan D. , Keane Susan P. , Shriver Lenka , Wideman Laurie , Shanahan Lilly 
Published: September 2022

OBJECTIVES
First, to leverage 15 years of longitudinal data, from child ages 2 to 17, to examine whether maternal depressive symptoms in early and middle childhood and in adolescence predict their child’s unhealthy behaviors during adolescence. Second, to examine whether the timing of maternal depressive symptoms or specific unhealthy behaviors matter and whether child depressive symptoms and body mass index explain these associations.

METHODS
Data came from a prospective-longitudinal community sample with multi-informant data (N = 213) from child ages 2 to17. A cumulative adolescent unhealthy behavior index was calculated, summing the presence of poor sleep, poor diet, physical inactivity, sedentary behavior, and smoking. Regression analyses examined associations of maternal depressive symptoms in early childhood (ages 2 to 5), middle childhood (ages 7 to 10), and adolescence (age 15) with adolescents’ unhealthy behaviors (ages 16 to17). Indirect effects of child depressive symptoms and body mass index were tested using a path model.

RESULTS
Adolescents’ unhealthy behaviors were common (eg, 2 out of 3 engaged in at least 1 unhealthy behavior). Higher levels of maternal depressive symptoms in middle childhood and adolescence were associated with adolescent engagement in more unhealthy behaviors at ages 16 to 17. Maternal depressive symptoms in early childhood were associated with adolescent unhealthy behaviors through indirect effects involving children’s depressive symptoms and continuity of maternal depressive symptoms.

CONCLUSIONS
Maternal depressive symptoms are associated with the number of adolescent unhealthy behaviors, both directly and indirectly. Promoting mothers’ mental health can be crucial for promoting children’s health behaviors and health.
Religious Tolerance in Minangkabau from a Psychological Perspective
Authors: Husna Mai Tiza , Ardias Widia Sri , Octavia Indah Andika 
Published: September 2022

Religious intolerance in Minangkabau is an issue that is often discussed recently, as reported in print and online media. This research aims to explain the psychological dynamics of the emergence of intolerant behavior and the efforts that can be made to increase religious tolerance from a psychological point of view. This research is a qualitative research with literature study. The results showed that there are 3 processes that occur when a person will take an action or not, the first is affective (positive or negative feelings about a group), psychological (open-minded thought) and behavior (tolerant or intolerant behavior).Intoleransi beragama di Minangkabau merupakan isu yang sering diperbincangkan akhir-akhir ini seperti diberitakan di media cetak dan online. Tulisan ini bertujuan untuk menjelaskan dinamika psikologis munculnya perilaku intoleran dan upaya yang dapat dilakukan untuk meningkatkan toleransi beragama dari segi psikologis. Penelitian ini merupakan penelitian kualitatif dengan studi pustaka. Hasil penelitian ini menunjukkan bahwa ada 3 proses yang terjadi ketika seseorang akan melakukan suatu tindakan toleransi atau intoleransi, yang pertama adalah afektif (perasaan positif atau negatif tentang suatu kelompok), psikologis (pikiran terbuka) dan perilaku (perilaku toleran atau intoleran).
PEMILIHAN GRUP UNTUK KRIPTOSISTEM GTRU
Authors: Hadi Abdul , Musraini Musraini , Gemawati Sri 
Published: September 2022

Kriptosistem kunci publik seperti NTRU yang berdasarkan pada grup, dikenal dengan nama GTRU (Group Theory Research Unit) [1]. Dalam pengkonstruksian GTRU, tidak semua grup dapat digunakan. Hal ini disebabkan proses dekripsi pada GTRU berhasil hanya pada grup dengan kondisi tertentu saja. Di [1], diberikan hanya dua contoh grup yang dapat digunakan untuk mengkonstruksi GTRU, yaitu grup ${{\mathbb{Z}}^{\{{{\phi }_{i}}:1\le i\le n\}}}$ yang isomorfis dengan ${{\mathbb{Z}}^{n}}$ dan grup poly-$\mathbb{Z}$ ${{G}_{n}}={{\mathbb{Z}}^{n-3}}\times \mathcal{H}$ dimana $\mathcal{H}$ adalah grup Heisenberg Diskrit yang dapat diaplikasikan pada internet of thing (IoT). Pada tulisan ini disediakan beberapa pilihan grup lain yang dapat digunakan dan tidak dapat digunakan untuk mengkonstruksi kriptosistem GTRU.