bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the relationship between hemodialysis-related glycemic variability and hormonal profiles in patients with type 2 diabetes on hemodialysis: a pilot study
Authors: Hayashi Akinori , Matoba Kenta , Ohata Yasuhiro , Shimizu Naoya , Suzuki Agena , Fujii Satoe , Sato Marie , Takano Koji , Shichiri Masayoshi 
Published: September 2022

Abstract
Background
The number of dialysis patients with diabetes is currently increasing in Japan and a similar proportion worldwide. It was suggested that approximately 20% of these patients had hypoglycemia after dialysis session and most of these hypoglycemia were unconscious. Furthermore, it was suggested that glucose variabilities induced by hemodialysis may be related to insulin and insulin-counter hormones, such as glucagon, adrenocorticotropic hormone (ACTH), and cortisol and growth hormone, but conclusive evidence has not still been obtained.

Methods
We investigated in detail the glucose and hormonal profiles in 7 patients with type 2 diabetes on hemodialysis (all male, HbA1c 6.8 ± 2.1%, glycated albumin 24.7 ± 10.2%). All participants were attached continuous glucose monitoring (iPro2®). Blood glucose level, C-peptide immunoreactivity, plasma glucagon, ACTH, cortisol and growth hormone were measured by 7 points blood tests at before breakfast, after breakfast (predialysis), 2 h and 4 h after starting dialysis, after lunch and before/after dinner on the dialysis day and 6 points at before/after each meal on the non-dialysis day, and these relationship with blood glucose dynamics were examined. The meal contents were set to the indicated energy amount, and the same menu was served daily for breakfast, lunch, and dinner on dialysis and non-dialysis days of this study period. In addition, the start time of lunch on non-dialysis day was the same as the start time of lunch on the dialysis day.

Results
Serum C-peptide level was significantly increased by taking breakfast and lunch on the hemodialysis day, significantly decreased during hemodialysis, and was significantly lower before and after lunch on the hemodialysis day than on the non-hemodialysis day. Plasma glucagon level significantly decreased during hemodialysis and that before lunch on hemodialysis day was significantly lower than on non-hemodialysis day. ACTH, cortisol, and growth hormone did not show any changes related to hemodialysis.

Conclusions
It was suggested that C-peptide and glucagon play an important role in hemodialysis-related glycemic variabilities in patients with type 2 diabetic hemodialysis.
Trial registration UMIN Clinical Trial Registry (Registration Number UMIN000018707). Registered 18 August 2015, https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr.cgi?function=brows&action=brows&type=summary&language=J&recptno=R000021647.
Face masks impair facial emotion recognition and induce specific emotion confusions
Authors: Rinck Mike , Primbs Maximilian A. , Verpaalen Iris A. M. , Bijlstra Gijsbert 
Published: September 2022

AbstractFace masks are now worn frequently to reduce the spreading of the SARS-CoV-2 virus. Their health benefits are undisputable, but covering the lower half of one's face also makes it harder for others to recognize facial expressions of emotions. Three experiments were conducted to determine how strongly the recognition of different facial expressions is impaired by masks, and which emotions are confused with each other. In each experiment, participants had to recognize facial expressions of happiness, sadness, anger, surprise, fear, and disgust, as well as a neutral expression, displayed by male and female actors of the Radboud Faces Database. On half of the 168 trials, the lower part of the face was covered by a face mask. In all experiments, facial emotion recognition (FER) was about 20% worse for masked faces than for unmasked ones (68% correct vs. 88%). The impairment was largest for disgust, followed by fear, surprise, sadness, and happiness. It was not significant for anger and the neutral expression. As predicted, participants frequently confused emotions that share activation of the visible muscles in the upper half of the face. In addition, they displayed response biases in these confusions: They frequently misinterpreted disgust as anger, fear as surprise, and sadness as neutral, whereas the opposite confusions were less frequent. We conclude that face masks do indeed cause a marked impairment of FER and that a person perceived as angry, surprised, or neutral may actually be disgusted, fearful, or sad, respectively. This may lead to misunderstandings, confusions, and inadequate reactions by the perceivers.
Coping with high advertising exposure: a source-monitoring perspective
Authors: Bell Raoul , Mieth Laura , Buchner Axel 
Published: September 2022

AbstractConsumers are exposed to large amounts of advertising every day. One way to avoid being manipulated is to monitor the sources of persuasive messages. In the present study it was tested whether high exposure to advertising affects the memory and guessing processes underlying source attributions. Participants were exposed to high or low proportions of advertising messages that were intermixed with product statements from a trustworthy source. In a subsequent memory test, participants had to remember the sources of these statements. In Experiments 1 and 2, high advertising exposure led to increased source memory and decreased recognition of the statements in comparison to low advertising exposure. High advertising exposure also induced an increased tendency toward guessing that statements whose sources were not remembered came from advertising. The results of Experiment 3 suggest that the presence of advertising, relative to its absence, leads to a skeptical guessing bias. Being exposed to advertising thus has pronounced effects on the memory and guessing processes underlying source attributions. These changes in source monitoring can be interpreted as coping mechanisms that serve to protect against the persuasive influence of advertising messages.
Power generation maximization of distributed photovoltaic systems using dynamic topology reconfiguration
Authors: Fang Xiaolun , Yang Qiang , Yan Wenjun 
Published: September 2022

AbstractThe ‘mismatch losses’ problem is commonly encountered in distributed photovoltaic (PV) power generation systems. It can directly reduce power generation. Hence, PV array reconfiguration techniques have become highly popular to minimize the mismatch losses. In this paper, a dynamical array reconfiguration method for Total-Cross-Ties (TCT) and Series–Parallel (SP) interconnected PV arrays is proposed. The method aims to improve the maximum power output generation of a distributed PV array in different mismatch conditions through a set of inverters and a switching matrix that is controlled by a dynamic and scalable reconfiguration optimization algorithm. The structures of the switching matrix for both TCT-based and SP-based PV arrays are designed to enable flexible alteration of the electrical connections between PV strings and inverters. Also, the proposed reconfiguration solution is scalable, because the size of the switching matrix deployed in the proposed solution is only determined by the numbers of the PV strings and the inverters, and is not related to the number of PV modules in a string. The performance of the proposed method is assessed for PV arrays with both TCT and SP interconnections in different mismatch conditions, including different partial shading and random PV module failure. The average optimization time for TCT and SP interconnected PV arrays is 0.02 and 3 s, respectively. The effectiveness of the proposed dynamical reconfiguration is confirmed, with the average maximum power generation improved by 8.56% for the TCT-based PV array and 6.43% for the SP-based PV array compared to a fixed topology scheme.
Evaluation of farnesol-induced changes in the haemocyte pattern of red cotton bug Dysdercus koenigii Fabricius (Heteroptera: Pyrrhocoridae)
Authors: Kumar Shailendra , Shazad Mohd , Kayesth Sunil , Gupta Kamal Kumar 
Published: September 2022

Abstract
Background
Dysdercus koenigii Fabricius is a polyphagous agricultural pest of paramount importance. Farnesol is a plant-derived open-chain aliphatic sesquiterpenoid alcohol. It is an intermediate in the metabolic pathway of juvenile hormone biosynthesis. The effects of Farnesol on haemocytes of fifth instar nymphs of Dysdercus koenigii were assessed in the present investigation. The early fifth instar nymphs were treated with doses of 0.05 μL, 0.1 μL and 0.2 μL Farnesol topically and day wise change in the total haemocytes was reported. Different types of haemocytes were identified in the haemolymph based on their morphological characteristics. Difference in day wise distribution pattern of haemocytes was evaluated in relation to dose of treatment.

Results
In normal fifth instar nymphs, age-related variation in the haemocyte count was evident; the haemocyte number increased up to four days and subsequently decreased till six-day when the nymph moulted. The results indicate that Farnesol had an adverse effect on the total number of haemocytes; in treated nymphs the haemocyte count decreased in a dose-dependent manner. The decrease was most prominent in the nymphs treated with a dose of 0.2 μL Farnesol. Based on the morphological characteristics, six different types of haemocytes, viz. prohaemocyte, plasmatocyte, adipohaemocyte, granulocytes, oenocytoids and disintegrated cells were identified in the haemolymph. The percent composition of different haemocytes showed variation depending on the age of the fifth instar nymph and the dose of treatment. In control, the percentages of plasmatocytes decreased up to day 5 and then increased up to 7 days. The percentage of adipohaemocytes increased throughout the nymphal period of the fifth instar, except for a small dip on the fourth day. Granulocytes and oenocytoids showed no clear trend. In Farnesol-treated nymphs, an increase in percent of prohaemocytes was observed in all the treatments. Dose-dependent effects were more prominent after day 5. An increase in plasmatocytes was seen after day 3. A distinct dose-related decrease was reported in adipohaemocytes on all days. Percent of disintegrated cells also showed an increase in all the tested doses of Farnesol on all the days. Granulocytes and oenocytoids showed no definitive trend of change.

Conclusions
Farnesol is a plant sesquiterpenoid and acts as a precursor in juvenile hormone biosynthesis. The application of Farnesol exogenously may disturb haemocyte patterns which may challenge the immune response of insects. Therefore, Farnesol can potentially be used as an alternative approach in pest management.
Screening for non-motor symptoms in Egyptian patients with Parkinson’s disease
Authors: Shaheen Shaimaa , Ali Raed Mohamed , Farghaly Marwa , El-Serafy Omar , Hegazy Mohamed I. 
Published: September 2022

AbstractBackgroundMost of the patients with Parkinson’s disease (PD) suffer from non-motor symptoms (NMS). Despite their marked effect on patients’ quality of life, NMS remain under-estimated by physicians, patients and caregivers. The aim of this study was to suggest a battery to screen for the presence of NMS in PD patients in the setting of an outpatient clinic and to assess the NMS of PD in Egyptian patients and factors affecting them.ResultsThis study was conducted on 50 patients with PD, 35 males (70%) and 15 females (30%) whom their age ranged from 36 to 80 years with a mean of 62.88 ± 8.74 years. All patients were assessed using the Movement Disorder Society Unified Parkinson’s Disease Rating Scale (MDS-UPDRS), Apathy Scale (AS), Montreal Cognitive Assessment (MOCA), Hamilton Depression Rating Scale (HDRS) and Parkinson’s Disease Sleep Scale (PDSS). The mean age at disease onset was 59.10 ± 9.34 years and the mean disease duration was 3.76 ± 3.16 years. 98% of patients (49 out of 50) had at least one non-motor symptom. The mean MDS-UPDRS scores were 15.74 ± 7.93 for part I, 17.94 ± 11.61 for part II and 42.32 ± 22.74 for part III. The mean score for AS was 9.90 ± 10.66 with 70% of patients considered apathetic. The mean MOCA score was 21.12 ± 4.73 with 38 patients (76%) found to be cognitively impaired. The mean HDRS score was 12.26 ± 8.52 with 34 patients (68%) found to be depressed. The mean PDSS score was 92.22 ± 32.53 with sleep disturbances found in 38 patients (76%). A statistically significant negative correlation was found between the HDRS and PDSS scores (Pvalue < 0.001). Age of patients, age at disease onset and disease duration were not correlated to MDS-UPDRS, AS, MOCA, HDRS and PDSS scores.ConclusionsMost of the patients with PD were found to suffer from NMS including apathy, cognitive impairment, depression and sleep disturbances. Physicians need to screen their PD patients for NMS on regular basis using the appropriate tools. Self-administered questionnaires could function as reliable screening tools for NMS in PD patients.
Co-creating cultures of sustainability and co-imagining the teaching green building: the use of a participatory Photovoice process in a HPGB context
Authors: Reimer-Watts Kai , Abel Esther , Coulombe Simon , Riemer Manuel 
Published: September 2022

AbstractDespite understanding the severity of the climate crisis, global action remains highly insufficient to address this challenge. Buildings are significant contributors to climate change due to their substantial global emissions, but can also contribute to urgent climate solutions. High-performance green buildings (HPGBs) can reduce operational building-level emissions dramatically, and potentially offer other benefits that support building users’ wellbeing and sustainable behaviours. HPGBs can provide useful environments to engage and influence culture and can act as publicly visible symbols of emergent local clean economies. However, a gap remains in knowing how best to support the emergence of citizen-led cultures of sustainability (COS) within green building spaces, an effort that could also help address the noted ‘performance gap’ of green buildings that has been linked to occupant behaviours. With the intention of investigating and supporting a growing citizen-led COS in a green building, this study applied an empowerment-based Photovoice method in the context of the HPGB evolv1, located in Waterloo, Ontario, Canada. Six building users (citizens) took and selected photographs, participated in facilitated group discussions and individual interviews, and contributed toward three public exhibitions based on research findings.Based on thematic analysis, findings suggest building citizens know what a COS means to them, and existing barriers and enablers within/around the evolv1 building toward achieving this. In addition, participants recognized the impact of specific green building features on their own personal sustainability-related values and practices, including the influence of sustainability symbolism within the building environment. Lastly, participants articulated specific recommendations for further promoting and growing a COS at evolv1. Significant themes identified are discussed in relation to and expansion of Cole (2014)’s Teaching Green Building (TGB) Model for Learning, providing preliminary insights into the degree to which evolv1 may or may not presently embody key aspects of a TGB. This study contributes to deepening understandings of how researchers and building citizens can support the emergence of COS within green buildings and related environments, with key takeaways that can be usefully applied to other settings, and theoretical and practical implications. Research findings encourage action toward supporting engaged, citizen-led COS, to advance more sustainable futures.
Ethnomedicinal applications, phytochemistry, and pharmacological properties of Laggera aurita Linn (Asteraceae): A Review
Authors: Julde Sa’adatu Muhammad , Borodo Safiya Bala , Wada Abubakar Sadiq , Ahmad Mubarak Hussaini , Malami Sani , Bichi Lawal Alhassan 
Published: September 2022

Abstract
Background
The plant Laggera aurita (Asteraceae) is a commonly utilized medicinal plant growing as a weed in African countries used in the treatment of many diseases. Besides, several phytochemical and pharmacological studies were conducted to check its phytocompounds and therapeutic potentials. However, there is unavailable information on the plant documenting its ethnomedicinal uses and medicinal properties. Therefore, the current article aims to provide updated information on the ethnomedicinal values, phytochemical compounds, and therapeutic potentials of Laggera aurita for further studies to develop noble bioactive molecules.

Main text
Studies regarding the plant Laggera aurita were sourced from online academic databases such as Google Scholar and PubMed. The search terms used include Laggera aurita, ethnomedicinal uses, phytochemistry, pharmacological activity, and toxicology. The plant has ethnomedicinal applications against epilepsy, cancer, atherosclerosis, thrombosis, malaria, fever, pain, stomatitis, asthma, bronchitis, nasal congestion, infections, rheumatism, dyspepsia, indigestion, constipation, dysentery, and many more. Several phytochemical agents were isolated from various plant parts. Besides, pharmacological studies have shown that the plant has antipyretic, analgesic, anti-inflammatory, anticonvulsant, anxiolytic, antimicrobial, antimalarial, and antioxidant effects.

Conclusions
Various pharmacological evaluations conducted on the plant have validated the traditional values of the plant Laggera aurita. However, more research is paramount to validate many of the reported traditional uses. Also, the phytochemical molecules need to be screened for biological properties to develop potential therapeutic agents. The plant is relatively safe on sub-chronic administration and slightly toxic in acute studies. Hence, further toxicological studies on the plant are required to establish its safety. There is a need to also standardize doses to establish safety and efficacy.
Chitosan impregnation of coconut husk biochar pellets improves their nutrient removal from eutrophic surface water
Authors: Thongsamer Thunchanok , Vinitnantharat Soydoa , Pinisakul Anawat , Werner David 
Published: September 2022

AbstractThe presence of excess nutrients in water resources can be harmful to human health and aquatic ecosystems. To develop an affordable water treatment method, the agricultural waste material coconut husk was converted into a low-cost adsorbent by thermal conversion to biochar, pelletized without (CH), and with chitosan (CHC), or eggshell powder (CHEG) modifications. The physical and chemical properties of all adsorbents were characterized using Brunauer-Emmett-Teller (BET) surface analysis, Fourier transform infrared spectroscopy, scanning electron microscopy, pHzpc, iodine number and elemental analysis. The adsorption of ammonium (NH4+), nitrate (NO3−), and phosphate (PO43−) in single and mixed solute solutions was investigated for initial concentrations of 10 mg L− 1. Langmuir, Freundlich, Sips, Dubinin-Radushkevich (D-R) and BET isotherm models were used to investigate the adsorption mechanisms. The maximum adsorption capacity of NH4+ on CH, CHC, and CHEG from mixed solute solution was 5.0, 4.7 and 5.9 mg g− 1, respectively, while the adsorption capacity of mixed:single solute solution was 0.95, 0.93, and 1.04, respectively. CH, CHC, and CHEG had greater ability to remove the cation NH4+ than anions NO3− and PO43− from aqueous solution. The highest maximum adsorption capacity for anions NO3− and PO43− was found on CHEG (1.7 mg g− 1) and CH (6.7 mg g− 1), respectively. NH4+ and NO3− were bound by chemisorption as indicated by D-R isotherm E values (> 8 kJ mol− 1), and enthalpy ∆H values (> 80 kJ mol− 1). In contrast, PO43− adsorption was mainly by physical interaction, including pore-filling, and electrostatic attraction. Pseudo first order and pseudo second order models provided good fits of the sorption kinetics data (R2 > 0.9). The initial concentrations of NH4+, NO3−, and PO43− in surface water sampled from a canal in Bangkok were 10.4, 1.2, and 3.9 mg L− 1, respectively, which indicated eutrophication. At a dose of 20 g L− 1, CHC achieved the best nutrient removal from this surface water, by 24% for NH4+, 25% for NO3−, and 66% for PO43− after 48 h contact, respectively.
Cadophora species from marine glaciers in the Qinghai-Tibet Plateau: an example of unsuspected hidden biodiversity
Authors: Zhang Bingqian , Li Xiaoguang , Li Guojie , Wang Qi-Ming , Wang Manman 
Published: September 2022

AbstractLarge numbers of marine glaciers in the Qinghai-Tibet Plateau are especially sensitive to changes of climate and surface conditions. They have suffered fast accumulation and melting and retreated quickly in recent years. In 2017, we surveyed the cold-adapted fungi in these unique habitats and obtained 1208 fungal strains. Based on preliminary analysis of ITS sequences, 41 isolates belonging to the genusCadophorawere detected. As one of the most frequently encountered genera, theCadophoraisolates were studied in detail. Two phylogenetic trees were constructed: one was based on the partial large subunit nrDNA (LSU) to infer taxonomic placement of our isolates and the other was based on multi-locus sequences of LSU, ITS, TUB and TEF-1αto investigate more exact phylogenetic relationships betweenCadophoraand allied genera. Combined with morphological characteristics, nineCadophoraspecies were determined, including seven new to science. Among the new species, onlyC. inflataproduces holoblastic conidia and all the others express phialidic conidiogenesis. All isolates have optimum growth temperature at 20 °C or 25 °C.With more species involved, the currently circumscribed genus became obviously paraphyletic. All members are clustered into two main clades: one clade mainly includes most of theCadophoraspecies which have phialidic conidiogenesis and we refer to as ‘Cadophora s. str.’; the remainingCadophoraspecies have multiform conidiogenesis and are clustered in the second clade, with members of other genera inPloettnerulaceaeinterspersed among the subclades. The results show a high diversity ofCadophorafrom marine glaciers in the Qinghai-Tibet Plateau and most of them are novel species.
Probiotic fermentation of polyphenols: potential sources of novel functional foods
Authors: Sharma Rohit , Diwan Bhawna , Singh Brij Pal , Kulshrestha Saurabh 
Published: September 2022

AbstractFermented functional food products are among the major segments of food processing industry. Fermentation imparts several characteristic effects on foods including the enhancement of organoleptic characteristics, increased shelf-life, and production of novel health beneficial compounds. However, in addition to macronutrients present in the food, secondary metabolites such as polyphenols are also emerging as suitable fermentable substrates. Despite the traditional antimicrobial view of polyphenols, accumulating research shows that polyphenols exert differential effects on bacterial communities by suppressing the growth of pathogenic microbes while concomitantly promoting the proliferation and survival of probiotic bacteria. Conversely, probiotic bacteria not only survive among polyphenols but also induce their fermentation which often leads to improved bioavailability of polyphenols, production of novel metabolic intermediates, increased polyphenolic content, and thus enhanced functional capacity of the fermented food. In addition, selective fermentation of combinations of polyphenol-rich foods or fortification with polyphenols can result in novel functional foods. The present narrative review specifically explores the potential of polyphenols as fermentable substrates in functional foods. We discuss the emerging bidirectional relationship between polyphenols and probiotic bacteria with an aim at promoting the development of novel functional foods based on the amalgamation of probiotic bacteria and polyphenols.
Graphical abstract