bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early chronotype with metabolic syndrome favours resting and exercise fat oxidation in relation to insulin‐stimulated non‐oxidative glucose disposal
Authors: Malin Steven K. , Remchak Mary‐Margaret E. , Smith Anthony J. , Ragland Tristan J. , Heiston Emily M. , Cheema Udeyvir 
Published: September 2022

New Findings
What is the central question of this study?
Chronotype reflects differences in circadian‐mediated metabolic and hormonal profiles. But, does resting and/or exercise fuel use differ in early versus late chronotype as it relates to insulin sensitivity?

What are the main finding and its importance?
Early chronotypes with metabolic syndrome utilized more fat during rest and exercise independent of aerobic fitness when compared with late chronotypes. Early chronotypes were also more physically active throughout the day. Greater fat use was related to non‐oxidative glucose disposal. These findings suggest that early chronotypes have differences in fuel selection that associate with type 2 diabetes risk.

AbstractEarly chronotypes (ECs) are often insulin‐sensitive, in part, due to physical activity behaviour. It is unclear, however, if chronotypes differ in resting and/or exercise fuel oxidation in relation to insulin action. Using the Morningness–Eveningness Questionnaire (MEQ), adults with metabolic syndrome (ATP III criteria) were classified as EC (MEQ = 63.7 ± 0.9, n = 24 (19F), 54.2 ± 1.2 years) or late chronotype (LC; MEQ = 47.2 ± 1.4, n = 27 (23F), 55.3 ± 1.5 years). Carbohydrate (CHO) and fat oxidation (FOX, indirect calorimetry) were determined at rest, 55% and 85% , along with heart rate and rating of perceived exertion. Physical activity patterns (accelerometers), body composition (DXA) and insulin sensitivity (clamp, 40 mU/m2/min, 90 mg/dl) with an indirect calorimetry for non‐oxidative glucose disposal (NOGD) were also determined. While demographics were similar, ECs had higher (P = 0.02), NOGD (P < 0.001) and resting FOX (P = 0.02) than LCs. Both groups increased CHO reliance during exercise at 55% and 85% (test effect, P < 0.01) from rest, although ECs used more fat (group effect, P < 0.01). ECs had lower sedentary behaviour and more physical activity during morning/midday (both, P < 0.05). FOX at 55% correlated with (r = 0.425, P = 0.004) whereas FOX at 85% related to NOGD (r = 0.392, P = 0.022). ECs with metabolic syndrome used more fat in relation to insulin‐stimulated NOGD.
Hexagonal Twist Origami Pattern for Deployable Space Arrays
Authors: Ynchausti Collin , Roubicek Clark , Erickson Joseph , Sargent Brandon , Magleby Spencer P. , Howell Larry L. 
Published: September 2022

Abstract
The hexagonal twist origami pattern has characteristics that made it a candidate for next-generation deployable space arrays. It has a deployed area that is up to 3.3 times larger than the stowed area, has a single-degree-of-freedom which simplifies actuation, it is flat-foldable making flat positions possible in both stowed and deployed positions, and its rigid foldability means that its motion is enabled by rotation about distinct axes without deformation of its panels. Although the pattern shows promise for deployable systems, it cannot be directly applied with thick materials because of the self-intersection of nesting panels. This paper presents the kinematics and mechanical advantages of the hexagonal twist pattern, addresses the self-intersection problem by implementing five different thickness accommodation techniques and provides metrics for comparing thickness accommodation techniques to determine which would be best suited for a given application. The concepts are demonstrated through two applications: a deployable reflectarray antenna and a LiDAR telescope.
Facile preparation of CoFe-based oxide nanosheets derived from CoFe-layered double hydroxide for the thermal catalytic decomposition of ammonium perchlorate
Authors: Gao Xia , Deng Peng , Han Kehua , Cao Yu 
Published: September 2022

In this work, CoFe-based oxide nanosheets were prepared by a facile method and its catalysis effects on the thermal decomposition of ammonium perchlorate (AP) were studied. CoFe-based oxide nanosheets were obtained from hydrothermal process and high-temperature treatment of CoFe-layered double hydroxide. The samples were characterized by scanning electron microscopy and high-resolution transmission electron microscopy. The thermal catalytic decomposition of AP with CoFe-based oxide nanosheets as catalysts was investigated by differential scanning calorimetry and coupling Fourier transform infrared spectrometer. The results showed that the CoFe-based oxide samples with the width size of 200–300 nm and the thickness size of ∼10 nm show the inherent catalytic ability. With 10 wt% of CoFe-based oxide nanosheets added, the decomposition temperature of AP was reduced by 127.5 °C from 431.0 °C to 303.5 °C. The apparent activation energy was decreased by 61.1 kJ/mol from 177.3 kJ/mol of raw AP to 116.2 kJ/mol of AP with 10 wt% of CoFe-based oxide nanosheets added. The thermal catalysis decomposition mechanism of AP with CoFe-based oxide nanosheet material promoting was proposed. This work offered a novel idea toward preparation and application of functional material layered double hydroxide in the field of energetic materials.
Rapid coastal erosion of ice-bonded deposits on Pelly Island, southeastern Beaufort Sea, Inuvialuit Settlement Region, western Canadian Arctic
Authors: Malenfant François , Whalen D. , Fraser P. , van Proosdij D. 
Published: September 2022

This paper quantifies rates of shoreline change and investigates the influence of surficial geology on shoreline dynamics between 1950 and 2018 on Pelly Island, located 10 km off the Mackenzie Delta. Long-term changes in shoreline position were calculated using imagery analysis and Analysing Moving Boundaries Using R (AMBUR). The influence of shoreline exposure to predominant storm direction and influence of surficial geology were examined for northwestern and southeastern zones. The average annual linear regression rate (LRR) rate during the 1950–2018 observation period was −3.8 m·a−1. The end point rate (EPR) was calculated for seven observation periods: 1950–1972, 1972–1985, 1985–2000, 2000–2018, 2000–2013, 2013–2018, and 1950–2018. A mean EPR of −5.5 ± 0.7 m·a−1 was calculated for the 2000–2018 period, and a maximum retreat rate of 46.7 ± 2.1 m·a−1 was recorded during the 2013–2018 observation period. By comparing the rate of change for sections of historical shorelines with differing surficial geology and exposure to storms, it was possible to draw conclusions on why Pelly Island continues to have the highest retreat rates in the Mackenzie–Beaufort region. Greater retreat rates were observed in lacustrine deposits (5.3 m·a−1) compared with moraine deposits (2.7 m·a−1). In addition, shoreline exposure to the predominant storm direction from the northwest was found to be a major influence on rates of shoreline change in all observation periods.
Space use and resource selection of Wood Turtles (Glyptemys insculpta) in the northeastern part of its range
Authors: Latham Sierra R. , Sirén Alexej P.K. , Reitsma Leonard R. 
Published: September 2022

The threats that affect a species often vary within its geographic range. Wood Turtles ( Glyptemys insculpta (Le Conte, 1830), formerly Clemmys insculpta (Le Conte, 1830)) are a species of concern due to widespread decline from anthropogenic threats. We studied two populations of Wood Turtles from June to September 2019 and 2020 to evaluate how landscape features and vegetative structure influenced space and habitat use and to identify potential risks in the remote, northern parts of its range. We hypothesized that space use would vary due to regional, landscape, and sex-specific differences. Turtles at the conifer-dominated site with higher road density had significantly smaller home ranges than the site with expansive and contiguous floodplains (7.25 ± 1.92 ha and 26.28 ± 6.77 ha, respectively). Females moved farther away from rivers than males (136.00 ± 23.68 m and 69.18 ± 34.81 m, respectively) and made the longest single-event movements. However, movements by males were significantly longer (34.65 ± 1.91 m) than females (23.99 ± 1.03 m) and followed rivers. At finer spatial scales, we found that turtles selected activity areas with complex vegetative structure and a more open canopy. Our study indicates that populations in contiguous forest could be critical to the conservation of Wood Turtles and we discuss management recommendations to reduce potential mortality risks in the northern part of its range.
Big Data Classification in IOT Healthcare Application Using Optimal Deep Learning
Authors: Akhtar MD Mobin , Ahamad Danish , Shatat Abdallah Saleh Ali , Shatat Ahmad Saleh Ali 
Published: September 2022

The Internet of Things (IoT) system is composed of several numbers of sensor nodes and systems, which are wirelessly interlinked to the internet. Generally, big data is the storage of a huge amount of information, which causes the classification process to be very challenging. Numerous big data classification approaches are implemented, but the computational time and secure handling of information are the major problems. The aim of the study is the development of big data approach in Internet of Things (IoT) healthcare application. Hence, this paper presents the proposed Dragonfly Rider Competitive Swarm Optimization-based Deep Residual Network (DRCSO-based DRN) for big data classification in IoT. First, the IoT nodes are simulated, and the heart disease patient data are collected through sensors. The routing is done using the Multi-objective Fractional Gravitational Search Algorithm (Multi-objective FGSA). In the Base Station (BS), the big data classification is done. Here, the classification is done using MapReduce (MR) framework, which includes two phases, like mapper and the reducer phase. The input data is initially fed to the mapper phase in the map-reduce (MR) framework. In the mapper phase, feature selection is carried out based on Dragonfly Rider Optimization Algorithm (DROA) in order to select the appropriate features for further processing. The DROA is modeled through merging Dragonfly Algorithm (DA) and Rider Optimization Algorithm (ROA). In the reducer phase, the classification is performed using DRN, which is trained by the developed DRCSO algorithm. The DRCSO is modeled by incorporating DA, ROA and Competitive Swarm Optimization (CSO). In addition, the performance of the developed method is outperformed than the existing approaches such as Linguistic Fuzzy Rules with Canopy Mapreduce (LFR-CM) + Fuzzy classifier, Machine learning-dependent k-nearest neighbors (FML-KNN), MapReduce-Fuzzy Integral-dependent Ensemble Learning Model+Single hidden layer feedforward neural network (MR-FI-ELM + SLFN) and DROA-recurrent neural network (RNN) based on the accuracy, average residual energy and throughput with the value of 0.929, 0.086[Formula: see text]J and 86.585. The proposed method is used to manage and derive meaningful information from the patient’s medical records, medical examinations results and hospital records.
Towards Porting Operating Systems with Program Synthesis
Authors: Hu Jingmei , Lu Eric , Holland David A. , Kawaguchi Ming , Chong Stephen , Seltzer Margo 
Published: September 2022

The end of Moore’s Law has ushered in a diversity of hardware not seen in decades. Operating system (OS) (and system software) portability is accordingly becoming increasingly critical. Simultaneously, there has been tremendous progress in program synthesis. We set out to explore the feasibility of using modern program synthesis to generate the machine-dependent parts of an operating system. Our ultimate goal is to generate new ports automatically from descriptions of new machines.
One of the issues involved is writing specifications, both for machine-dependent operating system functionality and for instruction set architectures. We designed two domain-specific languages: Alewife for machine-independent specifications of machine-dependent operating system functionality and Cassiopea for describing instruction set architecture semantics. Automated porting also requires an implementation. We developed a toolchain that, given an Alewife specification and a Cassiopea machine description, specializes the machine-independent specification to the target instruction set architecture and synthesizes an implementation in assembly language with a customized symbolic execution engine. Using this approach, we demonstrate the successful synthesis of a total of 140 OS components from two pre-existing OSes for four real hardware platforms. We also developed several optimization methods for OS-related assembly synthesis to improve scalability.
The effectiveness of our languages and ability to synthesize code for all 140 specifications is evidence of the feasibility of program synthesis for machine-dependent OS code. However, many research challenges remain; we also discuss the benefits and limitations of our synthesis-based approach to automated OS porting.
Catheter Ablation of Atrial Fibrillation in Patients With Heart Failure and Preserved Ejection Fraction
Authors: Zylla Maura M. , Leiner Johannes , Rahm Ann-Kathrin , Hoffmann Tobias , Lugenbiel Patrick , Schweizer Patrick , Scholz Eberhard , Mereles Derliz , Kronsteiner Dorothea , Kieser Meinhard , Katus Hugo A. , Frey Norbert , Thomas Dierk 
Published: September 2022

Background:
Coexistence of atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF) is common, affecting morbidity and prognosis. This study evaluates outcome after cryoballoon ablation for AF in HFpEF compared with patients without heart failure.

Methods:
A total of 102 AF patients with left ventricular ejection fraction ≥50% undergoing cryoballoon ablation were prospectively enrolled. Baseline evaluation included echocardiography, stress echocardiography, 6-minute walk test, biomarkers, and quality of life assessment (Short-Form-36). Procedural parameters and clinical, functional and echocardiographic end points at follow-up ≥12 months after AF ablation were compared between patients with and without HFpEF.

Results:

Patients with HFpEF (n=24) were older (median, 74 years versus 65 years;
P
=0.001) more often female (83% versus 28%;
P
<0.001) and characterized by more pronounced AF-related symptoms (median European Heart Rhythm Association score 3 versus 2;
P
<0.001), higher left atrial pressures (median, 14 mm Hg versus 10 mm Hg;
P
=0.008), reduced left atrial-appendage velocity (median, 36 cm/s versus 59 cm/s;
P
<0.001), and reduced distance in the 6-minute walk test (median, 488 m versus 539 m;
P
<0.001). Patients with HFpEF more often experienced AF recurrence (57% versus 23%;
P
=0.003), repeat AF ablation (39% versus 14%;
P
=0.01) and AF-related rehospitalization (26% versus 7%;
P
=0.016). Heart failure symptoms and elevated cardiac biomarkers persisted, even in patients with HFpEF with successful rhythm control at follow-up. Echocardiographic follow-up showed progression of adverse left atrial remodeling and no relevant improvement in diastolic function in HFpEF. Quality of life improved in patients without HFpEF, whereas patients with HFpEF still exhibited a lower physical component summary score (median, 41.5 versus 53.4;
P
<0.004).

Conclusions:
Patients with HFpEF constitute a distinct subgroup with elevated risk for AF recurrence after cryoballon ablation. Functional hallmarks of HFpEF persist, irrespective of rhythm status at follow-up. Future research is needed to optimize treatment strategies in patients with HFpEF.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT04317911.
Demographic and Regional Trends of Hypertrophic Cardiomyopathy-Related Mortality in the United States, 1999 to 2019
Authors: Minhas Abdul Mannan Khan , Wyand Rachel A. , Ariss Robert W. , Nazir Salik , Shahzeb Khan Muhammad , Jia Xiaoming , Greene Stephen J. , Fudim Marat , Wang Andrew , Warraich Haider J. , Kalra Ankur , Alam Mahboob , Virani Salim S. 
Published: September 2022

Background:
Hypertrophic cardiomyopathy (HCM)-related mortality has been decreasing within the United States; however, persistent disparities in demographic subsets may exist. In this study, we assessed nationwide trends in mortality related to HCM among people ≥15 years of age in the United States from 1999 to 2019.

Methods:
Trends in mortality related to HCM were assessed through a cross-sectional analysis of the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiological Research database. Age-adjusted mortality rates per 1 000 000 people and associated annual percent changes with 95% CIs were determined. Joinpoint regression was used to assess the trends in the overall, demographic (sex, race and ethnicity, age), and regional groups.

Results:
Between 1999 and 2019, 39 200 HCM-related deaths occurred. In the overall population, age-adjusted mortality rate decreased from 11.2 in 1999 to 5.4 in 2019. Higher mortality rates were observed for males, Black patients, and patients ≥75 years of age. Large metropolitan counties experienced pronounced declines in age-adjusted mortality rate over the study period. In addition, California had the highest overall age-adjusted mortality rate.

Conclusions:
Over the past 2 decades, HCM-related mortality has decreased overall in the United States. However, demographic and geographic disparities in HCM-related mortality have persisted over time and require further investigation.
Two Concepts of Cause in Antiphon’s Second Tetralogy
Authors: Kamtekar Rachana , Nichols Shaun 
Published: September 2022

Abstract
Using a framework from recent metaphysics and philosophy of science, according to which we have two concepts of cause, producer and necessary condition, we investigate causal notions in Antiphon’s Second Tetralogy, which concerns the unintentional homicide of a boy by a javelin-throwing youth. The prosecution maintains that the youth, having produced the boy’s death, is legally responsible; the defense argues, first, that the youth is patient, not agent, of a missing-the-target, and second, that the boy’s death depends on his running into the javelin’s path, so that identifying the cause requires evaluating the contrasts implicit in any causal claim.
Dog Dreams: Oneiric Representations of Interspecies Sociality among Middle-Class Young Adults in the United States
Authors: Sheriff Robin E. 
Published: September 2022

Abstract
The investigation of human dreaming offers significant insights to scholars of human-nonhuman animal studies. This article proposes that the ways in which companion species appear in humans’ dreams reveal the implicit ontological assumptions that undergird waking-life interspecies relationships. Focusing on dreams about dogs among middle-class U.S. college students, the analysis develops an updated model of dreaming that is synthesized from recent neuroscientific and anthropological theory-building. Themes of warm companionship, anxiety about dogs’ welfare, and preoccupations about their mortality suggest that dreams about dogs simulate and rehearse interspecies sociality in a cultural frame. They demonstrate both interspecies intersubjectivity and the significant place of canine persons in U.S. middle-class dreamers’ conceptualizations of their social networks. Such dreams challenge the public ideology of human exceptionalism, and suggest that human-canine sociality – in both waking and oneiric modes – may emerge as much from “egomorphic” as from anthropomorphic dispositions.
Entre l’âme et la Création. La dialectique et l’arithmétique de Simon Stevin
Authors: Coquard Jean-Marie 
Published: September 2022

Résumé
Les arts libéraux tiennent un rôle particulier dans la pensée de Simon Stevin (1548-1620). Grâce à eux, ce savant peut dévoiler dans son épistémologie d’une part ce que sont les dispositions innées de l’esprit (distinguer le vrai du faux, parler, compter) et d’autre part les fondements des objets de la Nature (le nom, le nombre, la mesure et le poids). Un art de penser associe alors l’âme et la Création et permet de codifier les différents arts et l’action vertueuse. Dans cet article, nous voulons montrer le rôle que jouent la dialectique et l’arithmétique dans l’art de penser de ce mathématicien et ingénieur flamand. Nous expliciterons alors les liens entre ces deux disciplines et la mise en place grâce à eux d’outils communs comme la proportion et la méthode dans la réalisation d’un projet encyclopédique.
Cavoatrial hypernephroma resection on cardiopulmonary bypass: Mild/normo-versus moderate hypothermia
Authors: Möbius Andreas , Grieshaber Philippe , Turra Jan , Riesterer David , Zaradzki Marcin , Soso Petar , Hatiboglu Gencay , Hohenfellner Markus , Warnecke Gregor , Tochtermann Ursula 
Published: September 2022

Introducion Renal cell carcinoma (RCC) is one of the most prevalent malignant tumors. It extends up into the systemic veins and right atrium. Surgical extraction of such extensions is usually carried out using cardiopulmonary bypass (CPB) with moderate hypothermic (MH) being frequently applied in order to obtain a clear surgical field. However, due to obvious disadvantages of hypothermia, approaches with mild/normothermia (NT) during CPB have also been established. The current study aims to compare the outcomes of patients undergoing RCC tumor and extensions resection using MH versus NT. Material and Methods This is a retrospective, non-randomized study. All patients who underwent RCC tumor and extensions resection for stage III or IV (Staehler) RCC in a single center between 2006 and 2020 were included. During surgery, MH or NT were applied. CPB was realized using aortic and bicaval cannulation. We compared the procedural times, transfusion requirements and postoperative outcomes, respectively between the MH and NT groups. Results A total of 24 consecutive patients (n(NT) = 12, n(MH) = 12) were included in the study (median age NT 68.5 and MH 66.5). The study only showed a significant difference in heart-lung machine times (median CPB time NT 45.5 min and MH 110.0 min, p = 0.004). All other results, loss of drainage, administration of blood products, as well as the postoperative course and mortality were comparable in both groups. Conclusion The results showed a high perioperative and long-term mortality. The perioperative course was similar after surgery with NT or MH. Therefore, NT which minimizes potential complications of MH should be preferred.