bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design of a Hydraulic Pump of Tractor for Manufacturing with 3D printer Technology
Authors: Al-Zaidi Ali 
Published: June 2022

In this work, a couple of spur gears design was changed by two double- helical gears design with maintaining other parts in the same size approximately for a hydraulic pump of agricultural tractor. The main purpose of this attempt was to obtain a new hydraulic pump with better specifications and performance. The new elements of the pump were designed using 3D Solid Works software then the stresses analyses and CFD analyses were archived using ANSYS software. The results showed a better flow rate of the hydraulic fluid by about 17%. This reflects the success of this idea where the flow rate of the new design was much higher compared with spur gear pump. This will conclude that the new design led to improve the pump performance. Moreover, the new pump overcomes the problems that usually appear in spur gears such as noise, vibration fracture. However, this design considers one of the most difficult parts in manufacture process therefor, it was recommended to fabricate it with3D printers
Entorno virtual de aprendizaje: las redes sociales para aprender en la universidad
Authors: Galván Orozco Ariadna , López Pérez Olga , Chávez López Joanna Koral , Contreras López Elsa Xanat 
Published: June 2022

La Tecnología de la Información y Comunicación (TIC) ha originado cambios en el contexto educativo, sin embargo, su incorporación a las escuelas no es sinónimo ni garantía de su uso como herramienta didáctica en el proceso de enseñanza y aprendizaje. En este trabajo se presenta el diseño, desarrollo y evaluación de una experiencia educativa que se realiza en el marco de una investigación cualitativa, la cual tuvo como objetivo implementar un Entorno Virtual de Aprendizaje (EVA) a través del uso de redes sociales para utilizarse como herramienta complementaria a la enseñanza presencial en la educación superior. Se realiza en el contexto de un curso complementario y optativo del programa de estudio de la licenciatura en Psicología de una universidad pública de la zona centro occidente de México. Los participantes fueron 74 estudiantes en un rango de edad de 19 a 27 años. El diseño de investigación se desarrolla en cuatro fases que integran el análisis de documentos y la triangulación múltiple. La primera fase corresponde al análisis curricular del plan de estudio; la segunda a la planeación tecno-pedagógica; la tercera a la elaboración de recursos didácticos, y la cuarta a la evaluación de la mediación docente. Se utilizó la red social de Facebook por las funciones de comunicación y difusión de información que ofrece, además de su diseño intuitivo. Así, se identificaron elementos clave sobre cómo las redes sociales pueden configurarse para utilizarlas como herramienta educativa complementaria al conformar un Entorno Virtual de Aprendizaje que promueve la autonomía, colaboración y el aprendizaje significativo.
Effect of repeated administration of a parenteral feline herpesvirus-1, calicivirus, and panleukopenia virus vaccine on select clinicopathologic, immunological, renal histologic, and immunohistochemical parameters in healthy adult cats
Authors: Summers Stacie C. , McLeland Shannon M. , Hawley Jennifer R. , Quimby Jessica M. , Lappin Michael R. 
Published: June 2022

Abstract

OBJECTIVE
To assess whether hyperinoculation of cats with a feline herpesvirus-1, calicivirus, and panleukopenia virus (FVRCP) vaccine could be used as a model to study interstitial nephritis and to assess humoral and cell-mediated immune responses toward vaccinal α-enolase.

ANIMALS
6 healthy young adult purpose-bred research cats.

PROCEDURES
Baseline renal cortical biopsies, whole blood, serum, and urine were collected prior to administration of a commercial FVRCP parenteral vaccine. Vaccine hyperinoculation was defined as a total of 8 vaccinations given at 2-week intervals over a 14-week period. Blood samples were collected immediately prior to each vaccination, and a second renal biopsy was performed 2 weeks after hyperinoculation (week 16). Renal histopathology, renal α-enolase immunohistochemistry, and assays to detect humoral and cell-mediated immune reactions against Crandell-Rees feline kidney (CRFK) cell lysates and α-enolase were performed. An α-enolase immunoreactivity score for renal tubules and glomeruli based on signal intensity was determined by a blinded pathologist.

RESULTS
Hyperinoculation with the vaccine was not associated with clinicopathologic evidence of renal dysfunction, and interstitial nephritis was not recognized by light microscopy in the time studied. The mean serum absorbance values for antibodies against CRFK antigen and α-enolase were significantly (P < 0.001) higher at weeks 4, 8, and 16 versus week 0. Renal tubular and glomerular α-enolase immunoreactivity scores were higher at week 16 compared to baseline.

CLINICAL RELEVANCE
Findings suggested that systemic immunological reactions occurred and renal tissues were affected by vaccine hyperinoculation; however, short-term FVRCP vaccine hyperinoculation cannot be used to study interstitial nephritis in cats.
Potential biomarkers for chronic seasonal heat stress in Kagoshima Berkshire pigs reared in the subtropical region
Authors: Ijiri Moe , Odo Kenji , Sato Motohiko , Kawaguchi Maiko , Fujimoto Yoshikazu , Miura Naoki , Matsuo Tomohide , Hou De-Xing , Yamato Osamu , Tanabe Takashi , Kawaguchi Hiroaki 
Published: June 2022

Abstract

Introduction
Potential biomarkers for chronic seasonal heat stress in Kagoshima Berkshire pigs reared in the subtropical region were investigated by comparing the biomarker changes in the summer (a period of chronic heat stress) and winter (a thermoneutral period) seasons.

Material and Methods
Pigs were allocated to summer- and winter-finishing cohorts, 12 each. The evaluations included assessment of carcass traits and internal organs’ normality carried out at the time of slaughter, and measurement of biomarkers in whole blood: derivatives of reactive oxygen metabolites (d-ROMs) and biological antioxidant potential as markers of oxidative stress, and serum amyloid A and albumin/globulin (A/G) ratio as markers of acute and chronic inflammation, respectively.

Results
The summer-finished pigs reared under subtropical field conditions showed lower carcass quality than the winter-finished pigs, indicating a potential adverse effect of summer temperatures on the swine industry. Marginal changes were observed in d-ROMs and the A/G ratio between the summer- and winter-finishing cohorts.

Conclusion
The results demonstrate that d-ROMs and the A/G ratio could be used as sensitive markers for heat stress under field conditions.
Uso de tabaco, álcool, drogas ilícitas e medicamentos na gestação, aspectos sociais e suas repercussões materno-fetais
Authors: Cury Ana Carolina Guedes , Campos Arthur Bernardo Gontijo Torres Nunez , Santos Beatriz Lélis , Miranda Lívia Alves , Santiago Millena Grossi Siervo , Melo Viviane Araújo Moreira de , Damianse Laura Alcântara , Penedo Maria Eduarda Millen , Zimmermmann Juliana Barroso 
Published: June 2022

Objetivo: Avaliar a prevalência de gestantes que utilizam drogas lícitas e ilícitas e correlacionar com os aspectos sociais e as repercussões materno-fetais. Métodos: Trata-se de um estudo caso-controle onde serão estudados prontuários de gestantes usuárias de drogas ilícitas e tabagismo. O estudo foi aprovado por Comitê de Ética em Pesquisa. Resultados: A amostra foi composta por 5841 gestantes, com idade média de 26,5 + 7,28 anos. O tabagismo se associou a menor idade da primeira relação sexual, menor idade da primeira gravidez, Crescimento Intrauterino Restrito (CIUR), etilismo, uso de drogas e abandono escolar. O consumo de drogas ilícitas foi associado a ITU alta, maior número de gestações, tabagismo, etilismo, bacteriúria assintomática, menor escolaridade e ao abandono escolar. O consumo de álcool foi associado à menor idade da primeira gravidez, menor idade da primeira relação sexual, tabagismo, uso de drogas, anemia e ao abandono escolar. Conclusão: O envolvimento das gestantes com as drogas, sejam lícitas ou ilícitas, mostram associação com desfecho obstétrico desfavorável e abandono escolar.
Spectral Studies of Analgesic, Antipyretic and Anti-Inflammatory Drugs Used in Medical Therapy in Romania
Authors: Rodica Sirbu , Ionescu Ana Maria , Jurja Sanda , Tomescu Cezar Laurentiu 
Published: June 2022

Abstract
Human health decline is most commonly manifested by pain and sometimes fever in the initial phase of the disease. Analgesics, antipyretics and anti-inflammatories serve as drugs with various chemical structures which showcase in different proportions their main actions. They represent medicines that suppress pain and fight fever. The aim of the paper is studying the usual types of therapeutic indications using modern spectral analysis, based on the analgesic, antipyretic and anti-inflammatory actions. The following spectral analysis methods are used to control the chemical compositions of the studied drugs: UV-VIS analyses and IR analyses.
Importance of Bioactive Compounds of Ganoderma lucidum Extract in Medical Field
Authors: Pascale Carolina , Sirbu Rodica , Cadar Emin 
Published: June 2022

Abstract

Ganoderma lucidum is a well-known medicinal mushroom with a long history, used as an ancient remedy for promoting health and increasing longevity. This species of Ganoderma genus is important for our study because it has an interesting chemical composition and pharmacological benefits such as immune suppressor, hypocholesterolaemia, hypotensive, antitumoral, antioxidant, anti-inflammatory agents, and more others. G. lucidum chemical composition has many compounds such as vitamins (mainly Vitamin E), polysaccharides, triterpenes and each one of them is offering a distinctive pharmacological effect. This species of Ganoderma medicinal mushroom is used extensively for its internal effect on improving immune system, hepatoprotective benefit and additionally, a large variety of people consume Ganoderma lucidum as tea infusion and coffee because its antioxidant and reducing stress effects.
A 50 años de la creación de las Carreras de Comunicación: la distancia entre la formación y el mercado
Authors: Blanco Cecilia , Ruiz Pereyra Magdalena 
Published: June 2022

Bastante se ha escrito sobre la distancia entre la formación que adquirieron los graduados de Comunicación y Periodismo de Latinoamérica y las demandas del mercado de trabajo. Sin embargo, pocos estudios se propusieron analizar, de manera historiográfica, las causas que explican dicha distancia. Para tratar de comprender estas causas, realizamos una investigación documental sistemática con intención historiográfica. Trabajamos con repositorios digitales e incorporamos artículos publicados en revistas indexadas, libros y capítulos de libros de algunos de los principales referentes de la comunicación de la región. Los resultados muestran que, si se quiere evitar la marginación de estos graduados por parte del mercado, podría ser necesario que las Facultades de Comunicación estudien integralmente tanto las características y evolución del sistema socioproductivo y el mercado, como las características y evolución de los currículos. Además de este aspecto, que consideramos crucial, podría ser relevante analizar las trayectorias educativas y laborales de los profesionales en un sentido longitudinal, y desarrollar investigaciones interdisciplinarias y transdisciplinarias sobre los problemas de las sociedades actuales, para, de este modo, estructurar mapas heurísticos y desarrollar planes de estudio flexibles y actualizados.
Study of Regions of Homozygosity (ROH) Patterns to Evaluate the Use of Dogs’ Genome in Human Drug Development
Authors: Smieszek Sandra , Polymeropoulos Mihael H. 
Published: June 2022

Animals are used as preclinical models for human diseases in drug development. Dogs, especially, are used in preclinical research to support clinical safety evaluations during drug development. Comparisons of patterns of regions of homozygosity (ROH) and phenotypes between dogs and humans are not well known. We conducted a genome-wide homozygosity analysis (GWHA) on the human and dog genomes. We calculated ROH patterns across distinct human cohorts, including the Amish, the 1000 genomes, Vanda 1 k genomes, and the Alzheimer’s cohort. The Amish provided a large cohort of extended kinships, allowing for in-depth family-oriented analyses. The remaining human cohorts served as statistical references. We then calculated ROH across different dog breeds, with emphasis on the beagle—the preferred breed used in drug development. Out of five studied human cohorts, we reported the highest mean ROH in the Amish population. We calculated the extent of the genome covered by ROH (FROH) (human 3.2 Gb, dog 2.5 Gb). Overall, FROH differed significantly between the Amish and the 1000 genomes, and between the human and the beagle genomes. The mean FROHper 1 Mb was ~ 16 kb for Amish, ~ 0.6 kb for Vanda 1 k, and ~ 128 kb for beagles. This result demonstrated the highest degree of inbreeding in beagles, far above that of the Amish, one of the most inbred human populations. ROH can contribute to inbreeding depression if it contains deleterious variants that are fully or partially recessive. The differences in ROH characteristics between human and dog genomes question the applicability of dog models in preclinical research, especially when the goal is to gauge the subtle effects on the organism’s physiology produced by candidate therapeutic agents. Importantly, there are huge differences in a subset of ADME genes, specifically the cytochrome P450 family (CYPs), which constitute major enzymes involved in drug metabolism. We should use caution when generalizing from dog to human, even if human and beagle are relatively close species phylogenetically. Doi: 10.28991/HEF-SP2022-01-02 Full Text: PDF
Índice Sintético para Medir la Calidad del Empleo en las Micro y Pequeñas Empresas del Ecuador
Authors: Basante-Garcés José Luis 
Published: June 2022

A nivel mundial el empleo no solo es el motor de la economía de un país, además, es un derecho que tienen todos los ciudadanos y que afecta directamente las condiciones de vida de la población activa. Todo ser humano tiene derecho a una calidad de vida digna para poder cubrir sus necesidades, tanto fisiológicas, de seguridad, de afiliación, de reconocimiento y autorrealización, por lo que se considera importante analizar no solo la generación de empleo, sino también la calidad del empleo existente en las Micro y Pequeñas Empresas en el contexto ecuatoriano. El objetivo de esta investigación es establecer un índice que sea capaz de medir la calidad del empleo de las Micro y Pequeñas Empresas. El mismo estará estructurado por múltiples determinantes, tales como: tipo de contrato, horas de trabajo, seguridad social y nivel de ingresos. La metodología a utilizar está asociada a un índice sintético creado por Stefano Farné que ha servido de base para diferentes estudios en la región. Finalmente, con todas las variables establecidas y con sus pesos respectivos se establecerá un modelo econométrico que medirá la calidad del empleo en las Micro y Pequeñas Empresas del Ecuador.
La Constante Búsqueda del Éxito en el Contexto de la Actual Crisis Económica
Authors: Flores-Batallas Efraín Armando 
Published: June 2022

Buscar el éxito es una constante en las personas, quienes requieren de orientaciones clave para alcanzarlo. No obstante, esa búsqueda usualmente se sustenta en aspiraciones netamente materiales, tales como: dinero, bienes, títulos académicos o de nobleza, lo cual distorsiona el verdadero sentido de lo que es alcanzar el éxito que debe apalancarse, más que nada, en aspectos intangibles que harán que el individuo alcance una dimensión más subjetiva, pero gratificante. Sobre la base de estas reflexiones se ofrecen, en este artículo, seis enseñanzas que pueden ser de valor agregado en la búsqueda del éxito tan anhelado.
Investigasi Awal Penggunaan Layanan Digital Perguruan Tinggi. Studi Kasus: IPB Mobile for Students
Authors: Ramadhan Dean Apriana , Ardiansyah Firman , Adisantoso Julio , Asfarian Auzi , Nurhadryani Yani 
Published: June 2022

Layanan digital pada perguruan tinggi menjadi suatu kebutuhan, terlebih lagi setelah pandemi Covid-19 mendisrupsi perguruan tinggi. Transformasi proses belajar mengajar dan kegiatan pendukungnya dari tatap muka menjadi daring membutuhkan suatu sistem pendukung yang inklusif dan dapat diakses oleh seluruh civitas perguruan tinggi. Pada tahun 2018, Institut Pertanian Bogor telah meluncurkan aplikasi IPB Mobile for Students yang menyediakan layanan-layanan bagi mahasiswa secara digital. Penelitian ini dilakukan untuk melakukan investigasi awal terhadap penggunaan aplikasi tersebut. Investigasi dilakukan dengan menggunakan survei terhadap 196 responden mahasiswa Institut Pertanian Bogor pada bulan Februari - Maret 2022. Kuesioner terdiri atas dua bagian, yaitu pertanyaan konteks untuk menggali penggunaan IPB Mobile for Students oleh mahasiswa serta pertanyaan terbuka untuk menggali umpan balik dari mahasiswa. Secara umum, hasil dari investigasi awal ini telah memperlihatkan wawasan terkait penggunaan layanan digital di IPB, terutama pada aplikasi IPB Mobile for Students. Terlihat bahwa layanan digital memegang peranan penting dalam proses belajar mengajar. Keterikatan mahasiswa dengan layanan digital mencerminkan perubahan pola atau transformasi terhadap proses standar pelayanan akademik di perguruan tinggi. Penelitian ini merekomendasikan penelitian-penelitian selanjutnya untuk mengkaji penggunaan layanan digital perguruan tinggi.
Kata Kunci: layanan digital, perguruan tinggi, transformasi perguruan tinggi, sistem informasi
Pembangunan Model Jaringan Saraf Tiruan untuk Memprediksi Kecenderungan Tipe Mediasi Orang Tua terhadap Penggunaan Internet oleh Anak
Authors: Puspita Indah , Priandana Karlisa , Hardhienata Medria Kusuma Dewi , Morley Peter John , Asfarian Auzi , Alatas Husin 
Published: June 2022

Mediasi orang tua sangat diperlukan agar dampak negatif penggunaan internet oleh anak yang tinggi di masa pandemi Covid-19 dapat diminimalisir. Penelitian ini dilakukan dengan membuat model jaringan saraf tiruan (JST) untuk mengetahui hubungan antara faktor dalam keluarga dan teknik mediasi orang tua di wilayah Bogor. JST penelitian ini dibangun menggunakan metode pembelajaran propagasi balik (backpropagation). Faktor dalam keluarga yang diteliti sebagai masukan JST adalah usia orang tua, pendidikan, jumlah anak, usia anak, durasi menggunakan internet, serta jumlah media sosial yang digunakan. Jenis mediasi orang tua yang digunakan sebagai luaran jaringan adalah mediasi aktif penggunaan internet umum, mediasi aktif penggunaan bersama, mediasi pasif penggunaan bersama, mediasi pembatasan aktivitas berinternet, mediasi pembatasan penggunaan internet secara umum, mediasi aktif keamanan internet, mediasi pemantauan, dan mediasi teknis penggunaan internet. Data diperoleh melalui survei terhadap 282 orang tua di wilayah Bogor pada Februari-Juni 2021. Penelitian ini telah membangun model JST untuk memprediksi kecenderungan tipe mediasi orang tua dengan mean-squared error sebesar 0.05132.Model yang dihasilkan dapat dikembangkan lebih lanjut menjadi aplikasi edukasi sederhana yang dapat digunakan oleh orang tua untuk mengetahui jenis mediasi yang mereka lakukan. Dengan lebih memahami jenis mediasi yang mereka lakukan, kami berharap orang tua dapat memiliki pemahaman lebih baik mengenai mediasi orang tua dan dapat menerapkan teknik mediasi yang paling sesuai dengan kondisi yang mereka alami untuk mewujudkan ketahanan keluarga.
Efektivitas Instagram sebagai Media Komunikasi Pemasaran Produk Pangan Olahan Hasil Perikanan UMKM Si Petek
Authors: Sabila Sheila Helwa , Amanah Siti 
Published: June 2022

Produk pangan olahan hasil perikanan UMKM Si Petek memiliki nilai jual dan memerlukan sebuah kegiatan komunikasi pemasaran, salah satunya dilakukan melalui media sosial instagram. Tujuan penelitian ini yakni menganalisis efektivitas instagram sebagai media komunikasi pemasaran produk pangan olahan perikanan UMKM Si Petek. Responden penelitian ini berjumlah 45 orang yakni pelanggan Si Petek yang ditentukan melalui non probability sampling. Variabel yang digunakan dalam penelitian ini yaitu karakteristik responden (umur, jenis kelamin, jenis pekerjaan, pendidikan, pendapatan, dan domisili) serta karakteristik pesan media sosial instagram (kelengkapan informasi, kejelasan informasi, desain visual, tipografi, dan frekuensi pengiriman pesan). Untuk mengukur efektivitas media sosial instagram @sipetek.id menggunakan EPIC model (empathy, persuasion, impact, dan communication). Hasil penelitian menunjukkan terdapat hubungan nyata antara pendapatan dengan kelengkapan informasi. Selain itu, dimensi empati dapat memengaruhi frekuensi pengiriman pesan, dimensi persuasi hanya mampu memengaruhi tipografi, dimensi dampak mampu memengaruhi umur, frekuensi pengiriman pesan, dan tipografi, serta dimensi efektivitas komunikasi dapat memengaruhi umur dan tipografi.
Assessment of physical activity level and glycemic control among patients with type-II diabetes mellitus.
Authors: Fatima Zahra  , Shabnam Naveed  , Abdul Malik  , Mohammad Athar Khan  , Rashid Naseem Khan  , Kiran Kumari  
Published: June 2022

Objective: To assess the physical activity level (PAL) and its impact on glycemic control in patients with T2DM. Study Design: Cross-sectional study. Setting: Darul Sehat Hospital, Karachi. Period: February 2021 to June 2021. Material & Methods: Patients with T2DM were included through convenience sampling method. The sample size was calculated by Open Epi Version 3 assuming 69% frequency of outcome in population, margin of error 5% and confidence level 95%. PAL was assessed by using the short version of the International Physical Activity Questionnaire (IPAQ-SF). Results: Out of 330 patients 225(68.2%) were female and 105(31.8%) were males. The mean age of subjects was 55.2 ± 8.32 and the mean duration of diabetes 9.6 ± 6.4 years. Of the patients, 122 (37%) had low, 175(53%) had moderate, and 33 (10%) had high PAL. The mean sitting duration was 527.4 (95% CI 516 to 538) minutes. The mean weekly total energy was 938 ± 1171 MET-min/week. Conclusion: Our majority of patients were engaged in moderate physical activity level. The study results imply convincing impact of physical activity level and glycemic control. Women and older age Pakistani diabetic patients do not meet the physical activity recommendations.
Várias interpretações do Catolicismo Popular no Brasil
Authors: Antoniazzi Alberto 
Published: June 2022

O tema que me foi confiado é muito abrangente. Pretendo abordá-lo apresentando de forma muito breve as principais interpretações do catolicismo popular brasileiro e oferecendo alguns elementos de avaliação crítica destas interpretações.
Por diversas razões, mas principalmente pela convicção de que mesmo as teorias científicas estão condicionadas pelo contexto em que surgem, seguiremos uma ordem histórica, mais do que sistemática, na apresentação destas «interpretações»...
Penerapan Model Inkuiri Terbimbing untuk Meningkatkan Percaya Diri dan Prestasi Belajar Siswa
Authors: Supriyono Supriyono , Sunarti Sunarti 
Published: June 2022

This research aimed to describe the application of guided inquiry model to improve student’s confidence in grade V SDN Kaligesingin science lesson, to describe the application of guided inquiry model to improve student achievement , and describing the effectiveness of the application of guided inquiry model to improve student achievement in grade V SDN Kaligesing in science learning. The design used was Mixed methods Research. The subjects of this research were the students of grade V SDNKaligesin. The data collection in this research was done by observation and test sheet. Based on the results of research conducted during three cycles, the results showed that the ability of teachers in applying guided inquiry model had increased during its implementation, student confidence also increased from cycle I to cycle III, in addition to student achievement had a significant increase of the cycle I until cycle III.