bluuebunny/crossref_metadata_2025_split huggingface dataset:
vACcine COnfidence amongst those living with alleRgy during the coviD pandemic (ACCORD): a scoping review protocol
Authors: Golding Michael A , Askin Nicole , Batac Ayel L R , Merrill Kaitlyn A , Abams Elissa M , Bégin Philippe , Ben-Shosan Moshe , Ladouceur Erika , Roos Leslie E , Protudjer Vladan , Protudjer Jennifer LP 
Published: April 2022

Abstract
Background Reports of allergic reactions to the COVID-19 vaccines have been documented, which may also contribute to hesitancy. Despite the low likelihood that the COVID-19 vaccine will trigger an allergic reaction, we and others have reported that families with allergy remain vaccine hesitant due to concerns of COVID-19-vaccine-triggered anaphylaxis.Objective To present our scoping review protocol, that will inform a forthcoming living scoping review in which we will investigate the peer-reviewed and grey literature on COVID-19 vaccine hesitancy and allergic disease and/or allergic reactions following a COVID-19 vaccine.Methods Informed by Arksey and O’Malley framework for methodological review, we have developed a search strategy with content and methodological experts, and which has undergone Peer Review of Electronic Search Strategies review. A search of 4 scientific databases, as well as gray literature, will be performed without restriction to articles by type of COVID-19 vaccine, or country of study, and will include publications in the 10 languages our team can handle. Bi-monthly search alerts based on the search strategy will be generated.Results The first search will result in a stand alone peer reviewed scoping review. Bi-monthly updates will be posted on a pre-print server. Depending on the volume of literature, these updates will be synthesized and submitted for peer-review at 6 and/or 12 months.Conclusion COVID-19 vaccine hesitancy amongst individuals with allergy persists, despite very low risk of serious adverse reactions. Our living scoping review, which includes multiple forms of knowledge translation, will be a rigorous way to address hesitancy.
A Theoretical Study to Estimate Milk Adulteration Using Surface Plasmon Technique
Authors: N Prathap , S. Arun Prakash 
Published: April 2022

Abstract
The Plasmonic surface plasmon resonance (SPR) device was used to develop a rapid, simple, and specific immunoassay to detect adulteration in milk. The rapid detection of adulteration such as Urea, Melamine, and Salmonella is a major concern for the food industry. In the present study, urea, melamine, and salmonella are detected in cow and buffalo milk using SPR based technique. The performance of the proposed sensor for urea detection in buffalo and cow milk is 37.952°/RIU and 38.44°/RIU, respectively. In contrast, the sensitivity detected by the proposed SPR sensor for the salmonella and melamine salmonella adulteration in the milk is 22.0025°/RIU and 179.125°/RIU, respectively.
Comparing Forces on the Fetal Neck in Breech Delivery in Lithotomy Versus All-fours Position: A Simulation Model
Authors: Fard Delnaz , Borchers Chiara , Philippeit Jill Caren , Philippeit Anja V. , Kaukemüller Laura R. , Higgins-Wood Lara R. , Papageorgiou Spyridon , Hillemanns Peter , von Kaisenberg Constantin S. , Klapdor Rüdiger 
Published: April 2022

Abstract
Purpose: To measure forces applied to the fetal neck, in a simulation model for breech delivery, in both lithotomy versus all-fours position.Methods: We used a Laerdal SimMom simulator and a Birthing Baby together with PROMPT Flex Software. The descent of the fetus was accomplished using the Automatic Delivery Module 2. The baby was always in breech position, the SimMom in either all-fours or lithotomy positions. Sensors were located inside the fetal neck region to simulate forces applied to the plexus.Results: The lowest force on the fetal neck region was recorded for the delivery in all-fours position without further maneuvers (mean force 58.70 Newton, standard deviation 2.54 N). As weight was added to the baby, the force increased (i.e. +500g, mean force 71.8 N, SD 3.08 N, p<0.001). Delivery in lithotomy position resulted in a mean force of 81.56 N (SD 19.55 N). The force significantly increased in case of delivery of the head without assistance from contractions (mean force 127.93 N, SD 23.10 N). In all-fours position the delivery of the fetal head from pelvic floor level without contractions (Frank´s Nudge maneuver) resulted in a mean force of 118.45 N (SD 15.48 N, p=0.02). Maneuvers for shoulder dystocia (the inverted type that can occur during breech delivery) led to significantly higher mean forces independent from birthing positions.Conclusion: Breech delivery in all-fours position was associated with the lowest force acting on the fetal neck in our simulation model.
Soil and Topographic Impacts on Vegetation Dynamics in Remnant Forest Patches of Este District, South Gondar Zone, Ethiopia
Authors: Dilnessa Gashaye , Zerihun Woldu , Sileshi Nemomissa , Enyew Adgo 
Published: April 2022

Abstract
Plants interact with soil, geophysical, and disturbances within their habitats. This research aims to investigate the impact of soil, geophysical, and disturbances on plant species diversity attributes (diversity, richness, and evenness) in five forest patches of Este District, South Gondar Zone, northwestern Ethiopia. Vegetation and environmental data were collected from 71 square sampling plots (400 m2 area), laid at parallel transects in the forest patches. We collected data on plant species attributes, soil (acidity (pH), cation exchange (EC), exchangeable sodium percentage (ESP), organic matter, organic carbon, available potassium, available phosphorus, total nitrogen, bulk density), geographic (altitude, slope, and aspect), and disturbance level of the habitats. The correlation in plant species diversity attributes and environmental parameters was performed using various functions in R statistical programming. The correlation analysis indicated that the plant diversity attributes were associated with EC and ESP negatively and pH positively; with altitude and disturbance (both negatively and positively depending on the range of the gradients). It is concluded that plant attributes interact with environmental conditions in a range of strengths of interactions. This study was based on small samples in a single district. Therefore, it would be helpful if future researchers could cover larger geographical areas with different land-use types and collect larger soil samples for evaluation of the impacts of most primary and secondary soil nutrients on the plant attributes. This would allow a more comprehensive analysis that would be beneficial for forest management and conservation strategies in a study region.
Thermodynamic principles for system biology and the patterns of flower pigmentation
Authors: Zhao Qinyi 
Published: April 2022

Abstract
The thermodynamic principles for system biology are reviewed and formulated, and then basic patterns of flower pigmentation are interpreted. Main thoughts: 1) any biological trait (color or function of a cell) is logically related to a thermodynamic system (or physiological system, signaling network of the cell); 2) the striped, speckled and circle are three basic patterns of flower pigmentation, the development of flowers is an irreversible process;; 3) the patterns of flower pigmentation is formed in flower development; 4) the flower cells can change its color in a period of development and this process is controlled thermodynamically; 5) there is giant space of physiology within an organism and within it numerous thermal states can appear under different conditions. In this theory, the dominant inheritance means that a gene contributes great to the thermodynamic stability of a trait related system; different genes can be interacted or integrated thermodynamically according to their contribution to the stability of its related system. By combination of Turing theory and our views, complex patterns of pigmentation could be explained theoretically.
Lubrication behavior of n-hexadecane on ZnO layer at the nanoscale:A molecular dynamic exploration
Authors: Ren Kaikai , Liu Lin , Li Jing , Pan Haijun , Wang Zhijian 
Published: April 2022

Abstract
In this work, the lubricating models of Cu-Zn alloy with and without the Zinc oxide (ZnO) layer were established. Molecular dynamics (MD) simulation is employed to investigate the lubrication behavior of n-hexadecane on the ZnO layer at the nanoscale. The diffusion of lubricant molecules, and the interaction and stick-slip effect between the friction pairs and the lubricants are systematically explored. The results show that the ZnO layer limits the diffusion of n-hexadecane molecules and the formed lubricating films in the model of the substrate with the ZnO layer are obvious and stable. During the sliding process, ZnO molecules have strong interaction with lubricants molecules and adsorb lubricants molecules on the surface to form adsorption film. The stick-slip effect in the lubricating films generates periodic shear stress and reduces the wear of the friction pair. The ZnO layer causes lubricants molecules to be arranged regularly on the surface into a stable structure to sustain the greater load.
SOX2 expression in the pathogenesis of premalignant lesions of the uterine cervix: its histo-topographical distribution distinguishes between low and high grade CIN
Authors: Moshi Jobran M. , Ummelen Monique , Broers Jos L.V. , Smedts Frank , Pathology Department , Cleutjens Jack P.M. , Litjens Rogier J.N.T.M. , Ramaekers Frans C.S. , Hopman Anton H. N. 
Published: April 2022

Abstract
Aims: SOX2 expression was evaluated in cervical intraepithelial neoplastic lesions (CIN1, 2 and 3). The SOX2 distribution patterns in the epithelial compartments were correlated to their genetic make-up and presence of HPV copies.Methods and Results: SOX2 expression levels and histological distribution patterns were studied in normal squamous epithelium and in p16 positive CIN lesions. Copy numbers of the SOX2, SOX17 and TERC genes and of chromosomes 1, 3q and 7, as well as HPV genotypes and viral physical status were correlated with SOX2 distribution patterns. In general SOX2 expression increased with severity of CIN, but a specific expression pattern was found in CIN3. This pattern was characterized by absence of SOX2 in the basal compartment of the epithelium and variable levels in the intermediate and superficial compartments. This SOX2 staining pattern is significantly associated with CIN3 (p=0.004), not found in CIN1 and seen only in a small fraction of the CIN2 lesions. The chromosome ploidy and gene copy numbers in the HPV positive basal cell compartments of CIN3 were normal, in contrast to CIN2 where aneusomic cells were detected in these layers. Conclusions: Based on the SOX2 immunostaining pattern CIN1 and CIN2 could be delineated from CIN3. These data shed new light on the pathogenesis and dynamics of progression in premalignant cervical lesions, as well as on the target cells for HPV infection. Sox2 staining patterns may become a useful marker to distinguish CIN3 from low grade CIN particularly in diagnostically challenging cases.
A Uncommon Cardiac Complication after Endoscopic Dilation of a Gastric Sleeve Stricture in an Obese Woman
Authors: Nguyen Hang , Ricci Brittany , Tse Chung Sang 
Published: April 2022

Abstract
Endoscopic balloon dilation is a widely accepted non-surgical therapeutic approach for managing gastrointestinal luminal strictures. While complication rates vary depending on endoscopist experience, patient clinical status, and the nature of the stricture, complication rates are generally low. We present a case of a rare, but serious, complication of marked bradycardia after an elective endoscopic dilation of gastrectomy sleeve anastomotic stricture.
Unraveling quinoproteins-based extracellular electron transport in humus-dependent respiratory growth of Methanosarcina acetivorans
Authors: Song Yuanxu , Li Ling , Du Kaifeng , Zhu Fanping , Song Chao , Yuan Xian-Zheng , Wang Mingyu , Wang Shuguang , Ferry James G. , Yan Zhen 
Published: April 2022

Abstract
Microbial respiration using humus plays a critical role in organic matter decomposition and biogeochemical cycling of elements in diverse natural environments. A longstanding recognition is that microbial respiration is achieved through extracellular electron transfer mediated by electrical pili or c-type cytochromes. Here, we describe the capability of humus-dependent respiratory growth of a methanogen, namely Methanosarcina acetivorans, which is a model for studying acetoclastic methanogenesis. A previously unexplored gene cluster that encodes cell surface quinoproteins was identified as being responsible for extracellular electron transfer. Pyrroloquinoline quinone was found to be a cofactor for the quinoproteins, providing electrical interplay sites with quinone moieties of humus. The membrane-bound methanophenazine, which is analogous to ubiquinone, participated in extracellular electron transfer, being potentially coupled with energy-conserving humus respiration. Given that these quinoproteins are widely distributed in methanogens, our findings extend the current understanding of microbial humus respiration in the context of global methane dynamics.
Sleep-disordered breathing in adults with precapillary pulmonary hypertension: Prevalence and predictors of nocturnal hypoxemia
Authors: Murta Marcia S. , Duarte Ricardo L. M. , Waetge Daniel , Gozal David , Cardoso Alexandre P. , Mello Fernanda C. Q. 
Published: April 2022

Abstract
Purpose
To evaluate the frequency of sleep-disordered breathing (SDB) and predictors of the presence of nocturnal desaturation in adults with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Methods
Outpatients with a hemodynamic diagnosis of precapillary pulmonary hypertension who underwent portable polysomnography were evaluated. Diagnosis and severity of SDB were assessed using three well-established respiratory disturbance index (RDI) thresholds: 5.0/h, 15.0/h, and 30.0/h, while nocturnal hypoxemia was defined by the average oxygen saturation (SpO2) < 90%. Multiple linear regression analysis evaluated the potential relationships among explanatory variables with the dependent variable (average SpO2 values), with comparisons based on the standardized regression coefficient (β). The R-squared (R2; coefficient of determination) was used to evaluate the goodness-of-fit measure for the linear regression model.
Results
Thirty-six adults were evaluated (69.4% females). The majority of the participants (75.0%) had SDB (26 with obstructive sleep apnea [OSA] and one with central sleep apnea [CSA]); while 50% of them had nocturnal hypoxemia. In the linear regression model (R2 = 0.391), the mean pulmonary artery pressure [mPAP] (β: -0.668; p = 0.030) emerged as the only independent parameter of the average SpO2.
Conclusion
Our study found that the majority of the participants had some type of SDB with a marked predominance of OSA over CSA, while half of them had nocturnal desaturation. Neither clinical and hemodynamic parameters nor the RDI was a predictor of nocturnal desaturation, except for mPAP measured during a right heart catheterization, which emerged as the only independent and significant predictor of average SpO2.
WITHDRAWN: Wear performance of Ti based alloy coatings on 316L SS fabricated by sputtering method – Relevance to Biomedical Implants
Authors: G.Godwin  , Priyan M.Shunmuga , Jaisingh S.Julyes 
Published: April 2022

Abstract
The present investigations are being carried out to encapsulate 316L SS with a Ti-based alloy coating fabricated by using PVD sputtering method. TiN, TiO2, and TiCoCr powders with prescribed process parameters are consecutively coated on 316L SS through PVD sputtering process with coating durations of 30, 60, and 90 minutes respectively. Further microhardness, surface roughness, microabrasion and adhesion strength tests were also carried out to determine the impact of the coating material and the influence of coating time on the coated surfaces. Comparing to uncoated substrate merely a 60% improvement in abrasion resistance was observed in TiCoCr coated samples. The XRD results confirmed the optimal formation of Ti alloy coatings with corresponding orientation over the SS substrates. Moreover, TiCoCr with a 90 minutes coating duration has much better surface characteristics than TiO2 and TiN. Thus it is preferable that the 90 min coating duration is optimal for coating in steel for bio implants.
An integrated skin cancer education program in renal transplant recipients and patients with glomerular disease
Authors: Thet Zaw , Lam Alfred King-yin , Ng Shu-Kay , Aung Soe Yu , Han Thin , Ranganathan Dwarakanathan , Newsham Stephanie , Borg Jennifer , Pepito Christine , Khoo Tien Kheng 
Published: April 2022

Abstract
Sun-protective strategies focusing on skin cancer awareness are needed in immunosuppressed patients at risk of skin cancers. The study aims to determine the effect of an integrated skin cancer education program on skin cancer awareness and sun-protective behaviours in renal transplant recipients (RTRs) and patients with glomerular disease (GD) treated with long-term immunosuppressants. A pilot prospective cohort study was undertaken in Central Queensland, Australia was undertaken among adult RTRs and patients with GD, who completed survey questionaries on skin cancer and sun-health knowledge (SCSK), sun-protection practices and skin examination pre- and post-education. Fifty patients (25 RTRs, 25 patients with GD) participated in the study. All of them completed questionnaires at pre-, 3-month post-education and 92%(n = 46) at 6-month post-education. There was a significant increase in SCSK scores from baseline at 3-months (p < 0.001) and 6-months post-intervention (p < 0.01). Improved knowledge was retained for 6 months after education. There were significant changes in 2 of 8 photoprotective behaviours at 6 months. Interventional education enhanced regular self-skin examination rate (p < 0.001) as well as the frequency of full skin checks by general practitioners (p < 0.001). Overall, RTRs had better compliance with sun-protective methods and higher skin examination rates by themselves and/ or general practitioners before and after the intervention of education compared to patients with GD. To conclude, an integrated skin cancer education program improved knowledge of skin cancer and skin health as well as the frequency of self-skin examination and formal skin assessments. However, improvement in patient compliance did not extend to other sun-protective practices.
Performance of NamSor to estimate the country of origin and ethnicity of 90,000 researchers based on their first and last names
Authors: Sebo Paul 
Published: April 2022

Abstract
Objective
We aimed to evaluate the performance of NamSor in determining the country of origin and ethnicity of researchers.
Methods
We selected the 22 countries whose researchers authored at least 1000 medical publications in 2020 and whose percentage of migrants was < 2.5% in 2020. Using PyMed, a Python library that gives access to PubMed, we extracted all publications in 2021 whose first author was affiliated with a university or research institute located in the selected countries (N = 89,906 articles). We calculated the proportion of misclassifications (= errorCodedWithoutNA) and the proportion of non-classifications (= naCoded) for three variables available in NamSor: continent of origin (Asia/Africa/Europe), country of origin and ethnicity. We added two other variables: continent#2 ("Europe" replaced by "Europe/America/Oceania") and country#2 ("Spain" and "Portugal" replaced by "Latin American country"). We repeated the analyses by removing all results with accuracy < 50%.
Results
For the full sample and the subsample, errorCodedWithoutNA was, respectively, 17.0% and 13.4% for continent, 6.7% and 3.6% for continent#2, 28.3% and 20.3% for country, 20.7% and 12.2% for country#2, 21.2% and 15.7% for ethnicity. For its part, naCoded was 0% and 18.3% for all variables, except for ethnicity (0% and 10.9%).
Conclusions
NamSor is accurate in determining the continent of origin of individuals from their first and last names, especially when using the modified variable and restricting the analysis to names with inference accuracy ≥ 50%. The risk of misclassification is higher with country of origin or ethnicity, but decreases, as with continent of origin, when using the modified variable (country#2) and the subsample.
Zero Percent of Terminally Ill Patients with Non-Cancer Receive Palliative Care Service During Hospital Admission
Authors: Kangtanyagan Chutima , Vatcharavongvan Pasitpon 
Published: April 2022

Abstract
Background
Terminally ill patients with non-cancer conditions admitted to a hospital may miss palliative care (PC) services opportunities. This study aimed to examine the missed opportunities for PC services among these hospitalized patients.
Methods
We conducted a cross-sectional study using electronic medical records of patients with non-cancer conditions admitted to internal medicine wards, intensive care units, and cardiac intensive care units. The patients who met the Supportive and Palliative Care Indicators Tool (SPICT) criteria were those with PC needs, and the patients who had advanced care plans or received PC consultation were those receiving PC service. We reported the proportions of PC needs and PC service and their associated factors with crude and adjusted odds ratios.
Results
Of 459 patients, 49.9% were female, and 92.6% were discharged alive. Their mean age was 63 years old, with an average of ten-day length of stay. Of the patients, 61.7% needed PC according to the SPICT’s criteria, and none received PC services. The patients with dementia/frailty, kidney disease, and heart disease had the highest missed opportunities (100%, 96.8%, and 91.3%, respectively). Age, the number of discharge medications, and length of stay were associated with PC needs, but some of these associations disappeared in subgroup analysis.
Conclusion
None of the terminally ill patients with non-cancer conditions in our study received PC services. The high proportions of patients with dementia/frailty, kidney disease, and heart disease missed such opportunities. A long length of stay and high numbers of discharge medications were associated with PC needs. Doctors and nurses can use these two factors as a trigger to assess PC needs among these patients.
Textese : To Minimise Cell Phone’s Memory
Authors: Shrawankar Urmila 
Published: April 2022

Abstract
SMS Lingo is a shortened language used for typing text messages in mobile phones. It is also known as Textese. SMS language is a parlance of English that sabotages letters and numbers to produce extreme brief words. Making the SMS files concise; helps in better utilization of storage space in mobile phones. In this paper, idea for optimized utilization of space for SMS files is proposed by using a compression technique. This technique is based on semantic dictionary on the SMS files. By default compression of SMS file is in the internal phone memory, saved in inbox, will help in optimizing the storage space required by normal SMS files. Making the SMS concise will help in holding maximum information in the 160 character space provided per short message supported by Global System for Mobile Communication (GSM). This in turn will reduce the cost and SMS traffic across the network.