bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of Calmodulin Binding Transcription Activator 1 (CAMTA1) gene and its putative genetic partners in the human nervous system
Authors: Alves Gilda , Ornellas Maria Helena , Liehr Thomas 
Published: August 2022

AbstractThe Calmodulin Binding Transcription Activator 1 (CAMTA1) gene plays a central role in the human nervous system. Here evidence‐based perspectives on its clinical value for the screening of CAMTA1 malfunction is provided and argued that in future, patients suffering from brain tumours and/or neurological disorders could benefit from this diagnostic. In neuroblastomas as well as in low‐grade gliomas, the influence of reduced expression of CAMTA1 results in opposite prognosis, probably because of different carcinogenic pathways in which CAMTA1 plays different roles, but the exact genetics bases remains unsolved. Rearrangements, mutations and variants of CAMTA1 were associated with human neurodegenerative disorders, while some CAMTA1 single nucleotide polymorphisms were associated with poorer memory in clinical cases and also amyotrophic lateral sclerosis. So far, the follow‐up of patients with neurological diseases with alterations in CAMTA1 indicates that defects (expression, mutations, and rearrangements) in CAMTA1 alone are not sufficient to drive carcinogenesis. It is necessary to continue studying CAMTA1 rearrangements and expression in more cases than done by now. To understand the influence of CAMTA1 variants and their role in nervous system tumours and in several psychiatric disorders is currently a challenge.
From encoding to retrieval: Change in level of unitization resolves debate about Unitization's effect on associative recognition
Authors: Liu Zejun , Li Xian , Li Xiaohuan , Yuan Jing , Guo Chunyan 
Published: August 2022

AbstractAlthough it is widely accepted that familiarity could support associative recognition when the to‐be‐learn items are ‘unitized’ into a new representation, the effects of unitization on associative recognition and recollection remain much debated. The current study aimed to explain these debates by exploring when and how unitization benefits associative recognition using event‐related potentials (ERPs). During the encoding phase, participants learned compound words and unrelated word pairs (i.e., High vs. Low level of unitization). At retrieval, the compound words were rearranged into new compound words (i.e., no‐change) and unrelated word pairs (i.e., change). Similarly, the unrelated word pairs were rearranged into new unrelated word pairs (i.e., no‐change) and compound words (i.e., change). Results showed that under the no‐change condition, unitization did not affect associative recognition, nor its underlying processes. In contrast, under the change condition, unitization improved associative recognition by increasing both familiarity‐related FN400 effect and recollection‐related LPC effect. In addition, a planned comparison between the compound‐change and unrelated‐no change conditions—a common index for unitization effect in past studies—revealed that unitization could not only elicit significant FN400 effect, but also improve associative recognition by increasing LPC effect. Collectively, these results not only allowed to explain the current discrepancies in the literature concerning the effect of unitization on associative recognition, but also emphasized the importance of matching the level of unitization between the studied and rearranged word pairs.
Study on antifriction mechanism of surface textured elliptical bearings
Authors: Wang Lili , Duan Jingdong , He Mengxue , Liu Ying'ao , Bao Yunlong 
Published: August 2022

Abstract
The surface micro texture can improve the surface tribological properties of friction pairs. As a two oil wedge bearing, elliptical bearing can restrain the journal whirl and maintain the stable operation. In the manuscript, the surface micro-texture is combined with elliptical bearing, and the influence of micro-texture shape, micro-texture depth and micro-texture radius on oil film pressure, bearing capacity and friction coefficient of elliptical bearing is studied by theoretical calculation and experimental research. The results show that with the increase of micro-texture depth, the bearing capacity first increases and then decreases; and when the dimensionless texture depth is 0.03, the bearing friction is the lowest and the bearing capacity is the highest. When the dimensionless radius of the micro texture is v3, the lubrication performance of the bearing is the best. When the shape of micro-texture is circle or triangular, the lubrication performance of elliptical bearing can be improved.
Experimental and Numerical Evaluation of Enzyme-Assisted Hot Waterflooding Performance for Heavy Oil Reservoirs
Authors: Zhang Chen , Hou Senhan , Ding Yanan , Wang Haiwen , Yang Daoyong 
Published: August 2022

Abstract
In this study, a systematical technique has been developed to experimentally and numerically evaluate enzyme-assisted hot waterflooding performance in a heavy oil reservoir for the first time. Experimentally, an enzyme solution (i.e., a protein-based liquid catalyst) is prepared and used to displace heavy oil in sandpacked experiments at elevated temperatures, during which pressures and fluid productions are continuously monitored and measured. Numerically, reservoir simulation is performed to reproduce the experimental measurements and then extended to evaluate the performance in a targeted heavy oil reservoir. Once history matching on the experimental measurements is completed, such a calibrated model is then employed to optimize enzyme concentration, temperature, and aging time, respectively. It is found from the displacement experiments that temperature imposes a significant impact on heavy oil recovery with its appropriate range of 45–55 °C, and enzyme positively contributes to heavy oil recovery for most scenarios. Compared to the traditional waterflooding mechanisms, the enzyme-assisted hot waterflooding process shows its considerable potential in heavy oil recovery by means of reducing oil viscosity, altering wettability, and reducing interfacial tension.
Enhancing Performance of Small Capacity Horizontal Axis Wind Turbine Using Grooved Linearized-Chord Blades
Authors: El-Askary W. A. , Sakr I. M. , Kotb M. A. , Abdelsalam Ali M. 
Published: August 2022

Abstract
In the current article, E216 airfoil blades with linearized chord of a small-scale horizontal axis wind turbine are numerically investigated to enhance the performance of the turbine. The blade is modified by including grooves on its suction side. Three-dimensional Reynold’s averaged Navier–Stokes (RANS) simulations are performed with Shear Stress Transport k–ω as a turbulence model. The computed power-coefficient results are first validated with previous measurements by the present authors on a wind turbine of 1 m rotor diameter at two wind speeds of 6 and 8 m/s. Another validation with measurements from the literature is performed via comparison of the pressure-coefficient distribution along surfaces of E216 airfoil at an angle of attack of 6 deg. Based on the successful computation, six different rotor models are numerically investigated with different numbers and locations of grooves created along the blade length, from the hub to the tip region, on the blade suction side. The lift and drag coefficients are compared for the different simulated rotor models. Furthermore, the torque coefficient, thrust coefficient, and static torque coefficient are obtained for the simulated models. It is found that the best-simulated configuration is Model 1 having one groove at 80% blade-chord length from the leading edge, with a maximum power coefficient of 0.429 at a tip-speed ratio of 4.75. The aerodynamic performance of the blades is strongly affected by the groove on the suction surface. The results show that Model 1 blade reduces the generated mean-axial force and its vibration frequency on the rotor.
Numerical Analysis of Combustion Dynamics in a Full-Scale Rotating Detonation Rocket Engine using Large Eddy Simulations
Authors: Pal Pinaki , Demir Sinan , Som Sibendu 
Published: August 2022

Abstract
Large eddy simulations (LES) using detailed chemistry and leveraging adaptive mesh refinement (AMR) are performed to gain insights into the combustion dynamics within a full-scale methane-oxygen non-premixed rotating detonation rocket engine (RDRE) employing impinging discrete injection schemes. In particular, a comparative analysis of two operating conditions corresponding to the same global equivalence ratio but different mass flow rates is carried out to investigate the resultant impact on detonation wave characteristics and RDRE global performance. Multiple co-rotating detonation waves with spatially-distributed wave structure and preferential alignment with the inner wall of the annulus (due to asymmetry in fuel distribution) are encountered under both conditions. Both cases exhibit pre-detonation deflagrative burning in the fill region, while one of the cases shows higher susceptibility to backflow into the feed plenums due to lower plenum pressures. Heat release analysis shows that the thrust obtained from the RDRE is closely linked to the distribution of total heat release between detonative and deflagrative combustion. On the other hand, combustion efficiency is associated with the fraction of heat release occurring in fuel-rich versus fuel-lean regions within the RDRE.
System Parameter Identification of a Colored-Noise-Driven Rijke Tube Simulator
Authors: Vishnoi Neha , Gupta Vikrant , Saurabh Aditya , Kabiraj Lipika 
Published: August 2022

Abstract
In this paper, we report an experimental investigation on the influence of colored noise (generated by the Ornstein–Uhlenbeck (OU) process) on thermoacoustic coupling in an electro-acoustic Rijke tube simulator. In the absence of noise, the simulator exhibits subcritical Hopf bifurcation. Although noise in a practical system has a finite correlation time, yet the system identification methods are based on the assumption of white noise. In this study, we investigate the effects of correlation time, and intensity of colored noise on the estimation of the growth rates of acoustic oscillations determined using Fokker–Planck equation in stable, bistable, and linearly unstable regions. Subsequently, we compare the findings against results obtained considering white noise approximations. We report the observed deviation of the estimated growth rates from the actual values as a function of noise intensity and correlation time. We find that with the colored noise model, the deviation in the estimated growth rates lies within the range of 0–10% compared to the deviation of 5–25% observed considering the white noise approximation. We also report that increasing noise amplitudes leads up to a deviation of approximately 30% in the estimated growth rates from the actual values.
Persistent subfoveal fluid in pneumatic retinopexy versus pars plana vitrectomy for rhegmatogenous retinal detachment: posthoc analysis of the PIVOT randomised trial
Authors: Bansal Aditya , Lee Wei Wei , Sarraf David , Sadda SriniVas R. , Berger Alan R , Wong David T , Kertes Peter J. , Kohly Radha P. , Hillier Roxane Jo , Muni Rajeev H. 
Published: August 2022

PurposeTo assess the incidence of persistent subfoveal fluid (PSFF) in pneumatic retinopexy (PnR) versus pars plana vitrectomy (PPV) following rhegmatogenous retinal detachment (RRD) repair and to determine its association with functional outcomes.MethodsPosthoc analysis of the PIVOT randomised trial. Eyes with gradable en face and cross-sectional spectral-domain optical coherence tomography (SD-OCT) scans at 1–2 months postoperatively were included. Primary outcome was the proportion of patients with PSFF following PnR versus PPV at 1–2 months postoperatively. Secondary outcomes included association of PSFF with Early Treatment Diabetic Retinopathy Study (ETDRS) letter score at 3, 6 and 12 months and metamorphopsia score (MCHARTs) at 12 months.ResultsOf 176 participants enrolled in PIVOT, 158 (89.8%) had gradable SD-OCT scans. Intergrader agreement was 0.870 (Cohen’s kappa). The incidence of PSFF was 16% (13/81) following PnR and 10.4% (8/77) following PPV (p=0.298; OR=1.65, 95% CI 0.64 to 4.23). Median ETDRS score at 3 months postoperatively between eyes with and without PSFF was 71 (IQR=58–78) and 78 (IQR=70–84), respectively (difference=7 letters, p=0.037), with no significant difference at subsequent 6-month and 12-month visits. Median metamorphopsia scores in patients with versus without PSFF were: horizontal: 0.1 (IQR=0–0.3) vs 0 (IQR=0–0.2) (difference=0.1, p=0.228) and vertical: 0.25 (IQR=0–0.4) vs 0 (IQR=0–0.2) (difference=0.25, p=0.148), respectively.ConclusionsThere was no significant difference in the incidence of PSFF in eyes undergoing PnR versus PPV for RRD. The presence of PSFF at 1–2 months postoperatively was associated with worse ETDRS letter score at 3 months, but there was no difference at 1 year.Trial registration numberNCT01639209.
Hand grip strength and ocular associations: the Ural Eye and Medical Study
Authors: Bikbov Mukharram M , Zainullin Rinat M , Gilmanshin Timur R , Iakupova Ellina M , Kazakbaeva Gyulli M , Panda-Jonas Songhomitra , Tuliakova Azaliia M , Fakhretdinova Albina A , Gilemzianova Leisan I , Jonas Jost B 
Published: August 2022

PurposeTo explore the associations between hand grip strength (HGS) and ocular parameters and diseases.DesignPopulation-based cohort study.MethodsParticipants of the Ural Eye and Medical Study, including 5899 (80.5%) out of 7328 eligible individuals aged 40+ years, underwent systemic and ophthalmological examinations including dynamometric HGS measurement.ResultsThe study included 5381 (90.4%) individuals (age: 58.6±10.6 years; range: 40–94 years) with HGS measurements. Higher HGS (mean: 30.6±11.7 dekaNewton) correlated (multivariable analysis) with better visual acuity (beta: 0.02, p=0.02), longer ocular axial length (beta: 0.03, p=0.003), higher intraocular pressure (beta: 0.03, p=0.001), thicker peripapillary retinal nerve fibre layer (beta: 0.03, p=0.001) and lower prevalence of diabetic retinopathy (beta: −0.03, p=0.007), after adjusting for younger age, male sex, Russian ethnicity, higher body height and waist to hip ratio, higher educational level, higher physical total score, lower smoking package years, higher serum concentration of haemoglobin, higher prothrombin index, lower leucocyte cell count, lower prevalence of non-alcoholic fatty liver disease, lower depression score and lower prevalence of arthritis. In the model, HGS was not correlated with prevalence of nuclear cataract (p=0.38), cortical cataract (p=0.67), subcapsular posterior cataract (p=0.50), open-angle glaucoma (p=0.22) or angle-closure glaucoma (p=0.27).Conclusions and relevanceIn addition to parameters such as lower physical activity, higher depression score and worse general health status, a reduced HGS is associated with visual impairment, shorter axial length, lower intraocular pressure, thinner peripapillary retinal nerve fibre layer and higher prevalence of diabetic retinopathy. HGS dynamometry or a handshake may provide the ophthalmologist additional clinical information about the general health and ocular parameters of the patient.
Drying Kinetics and Chemical Properties of Mango
Authors: Ampah Jonathan , Dzisi Komla Agbeko , Addo Ahmad , Bart-Plange Ato 
Published: August 2022

Four mango fruit varieties of average slice thickness 0.6 cm and slice area 10 cm2 were dried using a mechanical dryer at varied temperatures, 55°C, 65°C, and 75°C. In general, the moisture content (MC) for all samples analyzed decreased with increasing drying time. Palmer and Haden varieties recorded the lowest MCs of 8.7% (w.b.) and 9.3% (w.b.), respectively, when dried for 14 h at 65°C. Palmer variety with the highest initial MC of 87.2% (w.b.) recorded a low final MC of 8.7% (w.b.) when dried for 14 h at 55°C. Moisture ratio decreased from 1.00 to 0.13, 1.00 to 0.12, 1.00 to 0.12, and 1.00 to 0.10 at 55°C for Kent, Keitt, Haden, and Palmer varieties, respectively. Kent, Keitt, Haden, and Palmer varieties recorded effective moisture diffusivity values of

5.90
×

10

–
7

,

6.40
×

10

−
7

,

6.57
×

10

−
7

, and

7.33
×

10

−
7

m

2

/
s

, respectively. Vitamin C content of 158.34 mg/100 g recorded for Palmer was highest compared to the other varieties. Activation energy values of samples analyzed were between 19.90 and 25.50 kJ/mol for the drying temperature range. The activation energy recorded by Haden variety was highest compared to the rest. Also, twelve mathematical models were analyzed in predicting the moisture ratio of mango fruit slices during thin layer drying. The results showed that the Midilli, Page, Wang and Singh, and Logarithmic models exhibited supremacy in predicting drying behavior compared to the other eight models.
The Effects of Different Fertilizer on the Resistance of Tomato in Tomato Yellow Leaf Curl Virus (TYLCV)
Authors: Barrera Janet , Fuentes Mariecel 
Published: August 2022

The study aims to determine the resistance and evaluate the cost effectiveness of different organic fertilizer in tomato against Tomato Yellow Leaf Curl Virus (TYLCV). Four types of treatments were used, namely: Canaan Organic Fertilizer, Idol Organic Fertilizer, Synthetic Fertilizer and no fertilizer applied as control group. This study found that Treatment 4 (Synthetic Fertilizer) shows the highest height, least symptoms of TYLCV (yellowing and curling of leaves), and highest yield of tomatoes among the other treatments. Tomatoes applied with different fertilizers had no effect on the resistance against the Tomato yellow leaf curl virus. Once B. tabacci is present on the tomato host, there is a great chance of disease incidence.
Reducing Conversational Agents’ Overconfidence Through Linguistic Calibration
Authors: Mielke Sabrina J. , Szlam Arthur , Dinan Emily , Boureau Y-Lan 
Published: August 2022

Abstract
While improving neural dialogue agents’ factual accuracy is the object of much research, another important aspect of communication, less studied in the setting of neural dialogue, is transparency about ignorance. In this work, we analyze to what extent state-of-the-art chit-chat models are linguistically calibrated in the sense that their verbalized expression of doubt (or confidence) matches the likelihood that the model’s responses are factually incorrect (or correct). We find that these models are poorly calibrated, yet we show that likelihood of correctness can accurately be predicted. By incorporating such metacognitive features into the training of a controllable generation model, we obtain a dialogue agent with greatly improved linguistic calibration.
Embraces in Aeneid 8
Authors: Gramps Adrian 
Published: August 2022

Abstract
Venus and Vulcan, Venus and Aeneas, Pallas and Aeneas, Aeneas and Evander, Evander and Pallas: all of these pairs are seen embracing one another in Aeneid 8. Alongside these emotive scenes of embrace, the book is peppered with embrace-related vocabulary, imagery, and metaphor, often in surprising contexts. This article weaves together these embraces in Aeneid 8 in relation to the thematics of the book as a whole. It is proposed that, when read together, the embraces in Aeneid 8 tell a story about the possibilities of knowledge in relation to the senses. Vision is the supreme sense-modality of truth in epic, as embodied in the shield of Aeneas; and yet, in book 8, embrace emerges as a way of knowing that runs counter to optical discourses of knowledge. This leads to an exploratory reconsideration of hermeneutic principles in light of Aeneas’ much-puzzled-over response to the shield.
A Glass Half-Empty or Half-Full? An Assessment of the Labour Provisions in the CAI from Chinese and European Perspectives
Authors: Otteburn Kari , Marx Axel 
Published: August 2022

Abstract
The EU-China Comprehensive Agreement on Investment (CAI) presents a balancing act in labour rights protection. For the EU, labour rights protection constitutes an integral part of every trade and investment agreement it negotiates. China rarely includes labour provisions in trade and investment agreements. This article discusses current EU and Chinese approaches to integrating labour rights in trade and investment agreements, then introduces the provisions included in the proposed text of the CAI, and finally compares the proposed provisions in the CAI to the current approaches of the parties, focusing on five issues: international commitments, domestic labour regulation, dispute settlement, cooperation and stakeholder engagement. The article finds that from a European perspective, the CAI might represent a step back, while from a Chinese perspective, it might represent a step forward.
Obstacles, Opportunities, and Red Lines in the European Union: Past and Future of the CAI in Times of (Geo)-Politicisation
Authors: Burnay Matthieu , Raube Kolja 
Published: August 2022

Abstract
The conclusion and suspension of the Comprehensive Agreement on Investment (CAI) between the EU and China have been drawing substantial international academic attention over the last two years. To add to the ongoing debate, this article asks how one can best explain the conclusion and the suspension by the EU of the ratification of the CAI? And, secondly, the article focuses on the lessons which the EU can draw from the suspension of the CAI. By looking at the CAI background, negotiations and early ratification phase, the article sets out conceptually and empirically how a compartmentalisation and geo-politicisation of EU trade and investment policy contributed to the rise and fall of the CAI. Moreover, the article points to important lessons for future coherent and strategic investment policies. More specifically, it shows the need to bring together increasing investment flows with a sustained EU commitment to its very own founding values.
‘Day’ and ‘night’ in Latin
Authors: Nishimura Kanehiro 
Published: August 2022

Abstract
Although Latin is rich in vocabulary items for time, the history of their formation is not always clear. The adjectives and adverbs related to ‘day’ and ‘night’—diurnus ‘of the day’ / dius ‘by day’ and nocturnus ‘of the night’ / nox ‘by night’—are such cases and have not yet received fully satisfactory morphological explanations, particularly as to the -r- of the adjectives and the word-final sibilant of the adverbs, from either a Latin or an Indo-European perspective. Building upon traditional views, this paper offers a fresh approach to these forms. The results will then be applied to another temporal adjective, mēnstruus ‘of a month’, to clarify its phonological and morphological peculiarities.
Marshall on Salvation
Authors: Bock Darrell 
Published: August 2022

Abstract
This essay reviews I. Howard Marshall’s chapter on salvation as the core theological theme of Luke-Acts in Luke: Historian and Theologian. He contends for the idea of salvation being rooted in historical events and challenged Hans Conzelmann’s idea of the delay of the parousia. Jesus as Saviour and salvation in its broadest terms are at the center of Luke’s concerns. An assessment follows. Many have joined Marshall since in contending for a historically rooted portrait of the early church’s message. The idea of Jesus as Messiah-Lord may be a better central term for Luke’s Christology than Saviour. The theme of salvation as tied to reconciliation has brought focus to Luke’s emphasis on salvation. Also traced is the central role of geographical progression to point to the theme of Gentiles’ inclusion, as well as Paul’s career. The legacy of Marshall’s work still lives fifty years after this work.