bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bericht des Arbeitskreises „Baugruben“: Aktuelle und zukünftige Arbeiten
Authors: Hettler Achim , Kinzler Steffen 
Published: July 2022

AbstractDer Arbeitskreis „Baugruben“ der Deutschen Gesellschaft für Geotechnik (DGGT) veröffentlicht seit 1968 regelmäßig Empfehlungen für die Berechnung, Bemessung und Konstruktion von Baugrubenumschließungen. Die Empfehlungen liegen mit der EAB in geschlossener Form in der aktuell 6. Auflage vor. Der vorliegende Bericht gibt einen Überblick über die aktuellen und zukünftigen Arbeiten des Arbeitskreises. Im Berichtszeitraum erfolgten in der Hauptsache die Mitwirkung bei der Kommentierung der Entwürfe des neuen Eurocode 7, die Bewertung aktueller Erkenntnisse zur Ermittlung des Erdruhedruckbeiwerts und die Identifikation zukünftiger Themen für die weitere inhaltliche Bearbeitung der EAB.
Photoluminescence and thermoluminescence in Dy3+‐, Ce3+‐, and Tb3+‐activated MgB4O7 phosphor for dosimetry application
Authors: Oza Abha , Ojha Vibha , Dhale Shrikrishna , Dhoble Sanjay 
Published: July 2022

AbstractSamples of microcrystalline rare earth‐doped magnesium borate materials were synthesized via modified solid‐state diffusion and were characterized using X‐ray diffraction (XRD) and scanning electron microscopy (SEM) techniques. Photoluminescence (PL) results for the MgB4O7:Dy sample depicts blue emission that resulted from a 4F9/2–6H15/2 transition that peaked at 484 nm, which was much stronger than the yellow emission arising due to the 4F9/2–6H13/2 transition at 576 nm. From the emission spectra for MgB4O7:Tb, it seems that at higher concentrations of Tb3+ ion, the green emission becomes strong and directly relates to the energy transfer from the 5D3 excited state to the 5D4 excited state through a cross‐relaxation, whereas the blue emission is suppressed in MgB4O7 phosphors. The thermoluminescence (TL) of the samples was measured immediately after irradiation and compared by TL curve with CaSO4:Dy. MgB4O7:Dy showed very good TL sensitivity for the desirable dosimetric curve at ~218°C and the best glow curve structure. In comparison with the dosimetric peaks for MgB4O7:Ce and MgB4O7:Tb, the MgB4O7:Dy phosphor is equally sensitive to CaSO4:Dy. MgB4O7:Dy and MgB4O7:Tb showed linearity for a 1–5 kGy dose. The activation energies and frequency factors were also calculated for samples MgB4O7:RE (where RE = Dy, Tb, Ce) using the peak shape method.
Lateral branches of the facial artery and its clinical implications
Authors: Park Jung‐Ah , Yeo In‐Seung , Lee Hye‐In , Shin Hyun Jin , Koh Ki‐Seok , Song Wu‐Chul 
Published: July 2022

AbstractThe facial artery is the main artery supplying blood to the face and is known to have facial branches of the inferior labial, superior labial, lateral nasal and angular arteries. These known major branches of facial artery run medially, however, there are sometimes branches of the facial artery heading laterally. The purpose of the present study was to investigate the lateral branches of the facial artery in face. We dissected facial branches of the facial artery in 74 cadaveric hemifaces. We investigated the presence of the lateral branches of the facial artery. Following parameters were investigated: lateral branch presence, the location of its origin, and the lateral branch diameter. Among the lateral branches, we evaluated the prevalence and diameter of the premasseteric branch. Lateral branches were observed in 48 of the 74 hemifaces (64.9%). The total number was 81 in the 48 hemifaces. The most common origin was between the inferior border of the mandible and inferior labial artery origin (42 of 81, 51.9%). The mean diameter of all lateral branches of the facial artery was 0.7 mm. Among the lateral branches, the premasseteric branches were present in 38 of 74 specimen (51.4%) and the mean diameter was 0.8 mm. The lateral branches of the facial artery may be registered in Terminologia Anatomica based on their prevalence. Accurate knowledge of the anatomy of the lateral branches of the facial artery is helpful for clinicians to avoid complications during facial procedures or maxillofacial surgeries.
Suspected immune checkpoint inhibitor‐induced pulmonary sarcoid reaction in metastatic renal cell carcinoma
Authors: Purcell Victoria , Preti Beatrice , Fernandes Ricardo 
Published: July 2022

AbstractWe present the case of a 50‐year‐old male patient with metastatic clear cell renal cell carcinoma (mRCC) who developed a diffuse pulmonary opacification and lymphadenopathy during nivolumab maintenance therapy. This was diagnosed as presumed sarcoid granulomatous inflammatory reaction secondary to immunotherapy, which resolved with holding off therapy and the nivolumab was resumed.
Spondylocostal dysplasia and brachydactyly associated withTBX6andIHHvariants: A case report
Authors: Puvabanditsin Surasak , Gorbonosov Michelle , Blackledge Kristin , Manzano Jeffrey , Federici Matthew , Mehta Rajeev 
Published: July 2022

AbstractWe report a preterm male neonate presenting with a short trunk, short neck, low hairline, deformed ears, preauricular skin tag, penoscrotal transposition (PT), palmar crease, short and broad fingers and toes (brachydactyly), hypoplastic and deep‐set nails, metatarsal abductus, and cross‐fused, small echogenic kidneys. Radiologic findings and genetic studies are consistent with spondylocostal dysostosis (SCD) and autosomal dominant brachydactyly. This is the first case report of spondylocostal dysostosis and brachydactyly associated withTBX6andIHHvariants. We reviewed the literature and compared our patient's phenotype with previously reported cases of SCD.
Devastating salt‐wasting crisis in a four‐month‐old male child with congenital adrenal hyperplasia, highlighting the essence of neonatal screening
Authors: Reddy Nagaspurthy Anugu , Sharma Sucheta , Das Mainak , Kapoor Ashutosh , Maskey Upasana 
Published: July 2022

AbstractCongenital adrenal hyperplasia (CAH) is a rare condition usually referred to as a group of genetic disorders resulting due to a deficiency of steroid enzymes required by adrenal glands to produce cortisol and mineralocorticoid hormones. It has an autosomal recessive mode of inheritance and is further categorized into two types—Classic and Non‐Classic. Non‐Classic CAH is a more common milder form that presents late after puberty. Classic CAH, although more severe, is rare and detected at birth and is associated with the life‐threatening adrenal crisis in both sexes and virilization of the external genitalia in females (46, XX) patients, whereas in males, no overt abnormality of the external genitalia is present. We present a case of a four‐month‐old male child with the classic form of CAH who was brought with complaints of loose stools, projectile non bilious vomiting, decreased urine output, and failure to feed for 3 days. The child had a clinical presentation of salt wasting with hypoglycemia and hyperpigmentation of his genitalia. The USG findings revealed increased anteroposterior diameter of renal pelvis indicative of a growth in the suprarenal area. 17‐hydroxyprogesterone (17‐OHP) was found to be elevated confirming the diagnosis. He was treated with hydrocortisone with gradual improvement in his glucose and electrolytes. The patient was discharged home on replacement therapy consisting of oral prednisolone and fludrocortisone acetate and followed up as outpatient with significant improvement in the clinical findings. The fact that the child was not screened for CAH at birth led to the critical consequences of the disease in this case. To prevent life‐threatening adrenal crisis and help perform appropriate sex assignments for affected female patients, newborn screening (NBS) programs for the classical form of CAH should be made mandatory even in low‐ and middle‐income countries.
Post‐COVID‐19 splenic infarction in a patient with chronic atrial fibrillation: A case report
Authors: Sarmadian Roham , Ghasemikhah Reza , Sarmadian Hossein , Khosravi Mahmood , Hassani Saeed 
Published: July 2022

AbstractWe describe splenic infarction (SI), an infrequent condition, in an 82‐year‐old COVID‐19 patient with chronic atrial fibrillation (AF). COVID‐19 may cause thrombosis, and AF is a predisposing factor for splenic infarction. Suspicion of SI may be warranted in COVID‐19 patients with abdominal pain, especially if a predisposing factor exists.
AstraZeneca COVID‐19 vaccine: A possible risk factor for ischemic stroke and cerebral venous sagittal sinus thrombosis: A case series
Authors: Siddig Amira , Abbasher Hussien Mohamed Ahmed Khabab , Hassan Haroun Mazin S. , M. Abdallah Abdallah , Malekaldar Mohamed , Abbasher Al Hussien , Abbasher Mohammed , Abbasher Abubaker Alsedig , Hussien Abbasher 
Published: July 2022

AbstractOne of the most prevalent neurological impairments is cerebrovascular accident (CVA). Ischemic stroke and CVST have been linked to the AstraZeneca COVID‐19 vaccine. Three Sudanese patients developed these diseases after receiving the AstraZeneca COVID‐19 vaccine, indicating a relationship between the AstraZeneca COVID‐19 vaccine and these conditions.
Common peroneal nerve rupture with multiple ligament knee injury: A case report
Authors: Tada Kaoru , Matsuta Masashi , Akahane Mika , Murai Atsuro , Tsuchiya Hiroyuki 
Published: July 2022

AbstractIn peroneal nerve palsy with closed knee injury, most of the case improves by follow‐up. We present a case of peroneal nerve rupture with closed multiple ligament knee injury, requiring nerve transplantation. In multiple ligament knee injury, it is necessary to consider the possibility of peroneal nerve rupture.
Polyuria and polydipsia revealing a pituitary metastasis: Report of a rare case
Authors: Gader Ghassen , Guediche Skander , Ben Hadj Yahya Mohamed , Zouaghi Mohamed , Rkhami Mouna , Badri Mohamed , Zammel Ihsèn 
Published: July 2022

AbstractSellar region is a rare localization for intracranial metastases. The diagnosis is frequently delayed as symptoms are generally non specific. Radiologic diagnosis may be difficult as these tumours present similiraities to other more frequent sellar tumours. There is still no consensus regarding therapeutic approach. Prognosis is related to several features.
Arteriovenous malformation with pseudoaneurysm on the left upper limb
Authors: Furuta Akihisa , Futagami Daisuke , Morimoto Hironobu , Kitaura Junya , Mukai Shogo 
Published: July 2022

AbstractA 61‐year‐old woman developed a pulsatile mass on the left upper limb and was diagnosed with arteriovenous malformation with pseudoaneurysm. A two‐stage operation including ligation and resection of the aberrant branches and subsequent resection of the mass with revascularization was performed. Histological analysis suggested arteriovenous malformation and pseudoaneurysm.
Diagnostic evaluation and assessment of anemia in a patient with chronic kidney disease and gastrointestinal angioectasias undergoing hemodialysis
Authors: Courville Karen , Bernal Walter , Quiel Dimas , Pecchio Maydelin , Bustamante Norman , Landires Iván 
Published: July 2022

AbstractAnemia in patients with chronic kidney disease may have underlying causes that require a broad approach. Here, we present a clinical case of anemia in a patient with chronic kidney disease and gastrointestinal angioectasias undergoing hemodialysis.
Microscopic assisted excision of a rare posterior triangle branchial cyst
Authors: Sigdel Brihaspati , Neupane Bhima , Ranabhat Sunita , Pokhrel Amrit , Jha Ameet K. 
Published: July 2022

AbstractBranchial cyst is a painless mass commonly located in the anterior triangle of the neck. It is rarely found in the posterior triangle of the neck. A computed tomography scan of the neck is important to see the extent of the anomaly and its relationship with the major vessel.
Use of 3D printed model as a reconstruction aid in the management of an extensive ameloblastoma of the mandible
Authors: Odhiambo Walter A. , Gatune James M. , Guthua Symon W. , Muraguri Chris 
Published: July 2022

AbstractAmeloblastoma is a benign jaw tumor that can grow to a very huge size with high rate of recurrence. The large tumors pose a challenge during resection and reconstructive surgery. We present a massive ameloblastoma of the mandible that was surgically treated with the aid of 3D printed model.
Biocatalytic Friedel‐Crafts Reactions
Authors: Leveson‐Gower Reuben B. , Roelfes Gerard 
Published: July 2022

AbstractFriedel‐Crafts alkylation and acylation reactions are important methodologies in synthetic and industrial chemistry for the construction of aryl‐alkyl and aryl‐acyl linkages that are ubiquitous in bioactive molecules. Nature also exploits these reactions in many biosynthetic processes. Much work has been done to expand the synthetic application of these enzymes to unnatural substrates through directed evolution. The promise of such biocatalysts is their potential to supersede inefficient and toxic chemical approaches to these reactions, with mild operating conditions ‐ the hallmark of enzymes. Complementary work has created many bio‐hybrid Friedel‐Crafts catalysts consisting of chemical catalysts anchored into biomolecular scaffolds, which display many of the same desirable characteristics. In this Review, we summarise these efforts, focussing on both mechanistic aspects and synthetic considerations, concluding with an overview of the frontiers of this field and routes towards more efficient and benign Friedel‐Crafts reactions for the future of humankind.
Thermodynamic and kinetic study of fluorinated gas hydrates for water purification
Authors: Truong‐Lam Hai Son , Jeon Changsu , Lee Ju Dong 
Published: July 2022

AbstractThis study investigated and compared the thermodynamic stability, kinetic behaviour, and effectiveness of a water purification process using pentafluoroethane (HFC125a) and 1,1,1,2‐tetrafluoroethane (HFC134a) as guest molecules. The hydrate phase equilibria of each fluorinated gas (F‐gas) in pure water and NaCl solution were predicted using the Hu‐Lee‐Sum correlation, which agreed well with the experimental results from our previous studies. Under the same subcooling temperature of 3 K (at 0.3 MPa), the rate of hydrate growth with HFC134a was faster than that of HFC125a in the absence or presence of NaCl. In situ Raman spectroscopy confirmed that the HFC134a and HFC125a molecules occupy only a large cage of structure II hydrate. The Raman shifts of CH and CC bands in all phases (gas, liquid, and hydrate phases) of HFC125a shifted to higher wavelengths than those of HFC134a due to the increase in the number of fluorine atoms. The change in the salinity was studied to evaluate the effectiveness of an F‐gas hydrate‐based water purification process. In addition, the desalination efficiency of the HFC134a and HFC125a hydrates was compared by separating hydrate crystals from the slurries. The results showed that the desalination efficiency (or total dissolved solids removal efficiency) of HFC134a hydrate was higher than that of HFC125a hydrate. This study proves the importance of the water purification process using hydrates.
Environmental filtering rather than dispersal limitation dominated plant community assembly in the Zoige Plateau
Authors: Yang Jianping , Su Peixi , Zhou Zijuan , Shi Rui , Ding Xinjing 
Published: July 2022

AbstractIdentifying the mechanisms that underlie the assembly of plant communities is critical to the conservation of terrestrial biodiversity. However, it is seldom measured or quantified how much deterministic versus stochastic processes contribute to community assembly in alpine meadows. Here, we measured the decay in community similarity with spatial and environmental distance in the Zoige Plateau. Furthermore, we used redundancy analysis (RDA) to divide the variations in the relative abundance of plant families into four components to assess the effects of environmental and spatial. Species assemblage similarity liner declined with geographical distance (p < .001, R2 = .6388), and it decreased significantly with increasing distance of total phosphorus (TP), alkali‐hydrolyzable nitrogen (AN), available potassium (AK), nitrate nitrogen (NO3+–N), and ammonia nitrogen (NH4+–N). Environmental and spatial variables jointly explained a large proportion (55.2%) of the variation in the relative abundance of plant families. Environmental variables accounted for 13.1% of the total variation, whereas spatial variables accounted for 11.4%, perhaps due to the pronounced abiotic gradients in the alpine areas. Our study highlights the mechanism of plant community assembly in the alpine ecosystem, where environmental filtering plays a more important role than dispersal limitation. In addition, a reasonably controlled abundance of Compositae (the family with the highest niche breadth and large niche overlap value with Gramineae and Cyperaceae) was expected to maintain sustainable development in pastoral production. These results suggest that management measures should be developed with the goal of improving or maintaining suitable local environmental conditions.
Assessing an Elusive 3,4‐Dimethyl‐Chloroborole
Authors: Golfmann Maxim , Sindlinger Christian P. 
Published: July 2022

AbstractThe attempted syntheses of 3,4‐dimethylborole derivatives further bearing bulky SiMe2t‐Bu groups in 2,5‐position are reported. Isolation of base‐stabilized adducts to the chloroborole were achieved. The respective free borole was found to be unstable and revealed 1,3‐hydrogen atom shift isomerization to a 1‐bora‐1,3‐butadiene with an s‐trans orientation and lacking cyclic conjugation of the π‐system. Computational probing indicates elevated C−H acidity of methyl groups attached to the butadiene backbone in boroles, exceeding the C−H acidity of respective boron‐bound methyl groups. Derivatization attempts of the new chloroborole are reported.
Rapid Synthesis of Fused Polycyclic Heteroaromatics through Successive Vinylic/Aromatic C−F Bond Activation
Authors: Fujita Takeshi , Fukuda Takuya , Suzuki Naoto , Ichikawa Junji 
Published: July 2022

AbstractThe synthesis of fused polycyclic heteroaromatics was achieved via successive vinylic/aromatic carbon−fluorine (C−F) bond activation. The Suzuki‐Miyaura coupling of (1‐bromo‐2,2‐difluorovinyl)biaryls with 2‐hydroxy‐ or 2‐aminophenylboronic acids (esters) followed by defluorinative 5‐endo‐trig cyclization yielded 2‐fluorobenzofurans (indoles) with a biaryl moiety in one‐pot operation. The obtained 2‐fluorobenzoheteroles underwent acid‐mediated intramolecular C−F/C−H coupling to yield tetra‐, penta‐, and hexacyclic heteroaromatics. This protocol allowed the synthesis of various substituted benzo‐fused dibenzofurans and carbazoles.
Influence of CT image processing on the predicted impact of pores on fatigue of additively manufactured Ti6Al4V and AlSi10Mg
Authors: Gebhardt Ulrike , Schulz Paul , Raßloff Alexander , Koch Ilja , Gude Maik , Kästner Markus 
Published: July 2022

AbstractPores are inherent to additively manufactured components and critical especially in technical components. Since they reduce the component's fatigue life, a reliable identification and description of pores is vital to ensure the component's performance. X‐ray computed tomography (CT) is an established and non‐destructive testing method to investigate internal defects. The CT scan process can induce noise and artefacts in the resulting images which afterwards have to be reduced through image processing. To reconstruct the internal defects of a component, the images need to be segmented in defect region and bulk material by applying a threshold. The application of the threshold as well as the previous image processing alter the geometry and size of the identified defects. This contribution aims to quantify the influence of selected commercial image processing and segmentation methods on identified pores in several additively manufactured components made of AlSi10Mg and Ti6Al4V as well as in an artificial CT scan. To that aim, gray value histograms and characteristic parameters thereof are compared for different image processing tools. After the segmentation of the processed images, particle characteristics are compared. The influence of image processing and segmentation on the predicted fatigue life of the material is evaluated through the change of the largest pore in each set of data applying Murakami's empirical ‐parameter model.
NAD+ salvage governs mitochondrial metabolism, invigorating natural killer cell antitumor immunity
Authors: Guo Xiaowei , Tan Siyu , Wang Tixiao , Sun Renhui , Li Shuangjie , Tian Panpan , Li Mengzhen , Wang Yuzhen , Zhang Yankun , Yan Yuchuan , Dong Zhaoru , Yan Lunjie , Yue Xuetian , Wu Zhuanchang , Li Chunyang , Yamagata Kazuya , Gao Lifen , Ma Chunhong , Li Tao , Liang Xiaohong 
Published: July 2022

Background and Aims:
Natural killer (NK) cells are key players in tumor immunosurveillance, and metabolic adaptation manipulates their fate and functional state. The nicotinamide adenine dinucleotide (NAD+) has emerged as a vital factor to link cellular metabolism and signaling transduction. Here, we identified NAD+ metabolism as a central hub to determine the homeostasis and function of NK cells.

Approach and Results:
NAD+ level was elevated in activated NK cells. NAD+ supplementation not only enhanced cytokine production and cytotoxicity but also improved the proliferation and viability of NK cells. Intriguingly, the salvage pathway was involved in maintaining NAD+ homeostasis in activated NK cells. Genetic ablation or pharmacological blockade of nicotinamide phosphoribosyltransferase (NAMPT), the rate‐limiting enzyme in the NAD+ salvage pathway, markedly destroyed the viability and function of NK cells. Mechanistically, NAD+ salvage dictated the mitochondrial homeostasis and oxidative phosphorylation activity to support the optimal function of NK cells. However, in human HCC tissues, NAMPT expression and NAD+ level were significantly down‐regulated in tumor‐infiltrating NK cells, which negatively correlated with patient survival. And lactate accumulation in the tumor microenvironment was at least partially responsible for the transcriptional repression of NAMPT in NK cells. Further, deficiency of Nampt in NK cells accelerated the growth of HCC and melanoma. Supplementation of the NAD+ precursor nicotinamide mononucleotide (NMN) significantly improved NK antitumor response in both mouse and human cell‐derived xenografts.

Conclusions:
These findings reveal NAD+ salvage as an essential factor for NK‐cell homeostasis and function, suggesting a potential strategy for invigorating NK cell–based immunotherapy.
Prevalence of anxiety and depressive disorders in pregnant women with malignancy
Authors: Matsuo Koji , Duval Christina J. , Youssefzadeh Ariane C. , Mandelbaum Rachel S. , Ouzounian Joseph G. , Wright Jason D. 
Published: July 2022

AbstractObjectiveTo examine national‐level prevalence of anxiety and depressive disorders among pregnant women with malignancy.MethodsThis is a pre‐planned secondary analysis of a previous retrospective cohort study using the Healthcare Cost and Utilization Project's National Inpatient Sample. Study population was 14 648 135 deliveries including 10 145 patients with malignancy from 2016 to 2019. A multivariable binary logistic regression model was fitted to assess the association of malignancy and anxiety or depressive disorder.ResultsPregnant women with malignancy were 49% more likely to have the diagnosis of either anxiety or depressive disorder compared with those without malignancy (prevalence rate 114 vs. 61 per 1000 cases, adjusted odds ratio [aOR] 1.49, 95% confidence interval [CI] 1.40–1.58). The increase in the risk associated with malignancy on either anxiety or depressive disorder was more than two‐fold among patients with brain and other nervous system tumors (aOR 2.69, 95% CI 2.01–3.60), bone and joint tumors (aOR 2.32, 95% CI 1.33–4.04), and leukemia (aOR 2.12, 95% CI 1.81–2.48).ConclusionsThis national‐level analysis suggests that pregnant women with malignancy experience increased rates of psychological distress more often than pregnant women without malignancy.