bluuebunny/crossref_metadata_2025_split huggingface dataset:
HessHist: A Hessian‐matrix weighted histogram for image contrast enhancement
Authors: Fan Junchao , Zong Xuyang , Tang Han , Bi Xiuli , Xiao Bin , Li Weisheng 
Published: February 2022

AbstractFor image contrast enhancement operation, it is a keypoint to obtain more natural enhanced results and keep more details without distortion. In this paper, a novel image Hessian‐matrix weighted histogram for image contrast enhancement is proposed, which can improve the contrast of smooth regions and simultaneously restrain the contrast of texture regions. In the proposed method, the multi‐scale fractional‐order Hessian‐matrix is firstly utilized to detect and quantify the texture information of the input image, which explores the regions that should be contrasted or should be restrained. Then, the strong texture regions are suppressed by a designed suppress function. Finally, the information on unsuppressed regions and suppressed texture regions will be count by a histogram, which is termed as Hessian‐matrix weighted Histogram (HessHist) in this paper. According to HessHist, the corresponding cumulative distribution function will realize the contrast enhancement operation on the input image. For real‐time application, the integral images are introduced for fast computation of the HessHist. Experimental results show that the proposed HessHist‐based image enhancement algorithm preserves more details of input image without distortion, and is competitive with state‐of‐the‐art image enhancement algorithms in both subjective visual perception and objective evaluation metrics.
Prediction using long short‐term memory networks in the service of designing a novel pricing policy for smart grid
Authors: Mousavi Ziabari Zahra , Pasdar Abbas 
Published: February 2022

AbstractDynamic pricing is one of the most effective solutions for controlling and managing power consumption in the electricity markets. Two challenging issues to achieve this goal are to design a comprehensive policy, which can determine optimal prices for every party, and define an accurate simulator of the real environment, which can express the complexity of the satisfaction. To overcome these problems, we innovatively design an applicable and reliable policy that can determine the optimal price from every electricity market parties' point of view. Moreover, in this policy, satisfaction and profit coefficients are defined for the retailer and the customer, and then a step‐by‐step simulation is presented based on them. The proposed algorithm simulates interactions between the customer and retailer to reach an optimal point with improved performance. Furthermore, to increase flexibility and accuracy of the results, which make the system commercially operational, two long short‐term memory networks predict wholesale price and power demand will be utilised by the pricing section. For efficiency evaluation, the proposed method is compared with similar work to prove better precision and performance.
Digitale 3-D-Monitor-„Heads-up“-Kataraktchirurgie: Sicherheitsprofil und Vergleich zum konventionellen Mikroskopsystem
Authors: Bedar Mohammad Seleman , Kellner Ulrich 
Published: February 2022

Zusammenfassung
Fragestellung Ziel der Studie ist ein Vergleich hinsichtlich der Komplikationsraten von Kataraktoperationen zwischen einem digitalen 3-D-Monitor-„Heads-up“-System und einem
konventionellen binokularen Mikroskopsystem in einer großen Serie von Kataraktoperationen, durchgeführt von einem Operateur.
Methodik Die retrospektive Analyse umfasst eine konsekutive Serie von 2000 Augen, die wegen einer Katarakt operiert wurden, davon n = 1000 (3-D-Gruppe) unmittelbar nach Einführung
eines 3-D-Systems (Alcon Ngenuity) und n = 1000 als letzte Gruppe vor dessen Einführung mit einem konventionellen binokularen Operationsmikroskop (BM-Gruppe). Dabei wurde das 3-D-System auf
das vorhandene Mikroskop angepasst, sodass die Mikroskopoptik unverändert blieb. In beiden Gruppen wurde entweder eine Femtosekundenlaser-Kataraktoperation (Femto-Cat) oder eine
traditionelle Phakoemulsifikation durchgeführt. Es wurden retrospektiv Komplikationen erfasst und analysiert.
Ergebnisse Der Anteil von Femto-Cat betrug in der 3-D-Gruppe 19,8% und in der BM-Gruppe 18,6%. Eine Kapselruptur trat bei 10 Augen auf (3-D: n = 4 Augen [0,4%], vordere Vitrektomie:
n = 2, Pars-plana-Vitrektomie: n = 1; BM: n = 6 [0,6%], vordere Vitrektomie: n = 4, Pars-plana-Vitrektomie: n = 1). Ein vorübergehender Irisprolaps trat bei 3 Augen auf (3-D: n = 2, BM:
n = 1). In 2 Augen kam es zu einer Zonulolyse (3-D: n = 1, BM: n = 1). Insgesamt zeigte sich kein statistisch signifikanter Unterschied zwischen den beiden Gruppen (p > 0,5). Die OP-Zeit
verlängerte sich mit dem 3-D-System nicht signifikant.
Schlussfolgerung In einer großen Serie von 2000 Augen zeigte sich hinsichtlich des Sicherheitsprofils bei Kataraktoperationen kein signifikanter Unterschied zwischen der 3-D- und der
BM-Chirurgie. Die 3-D-Chirurgie ist für die Katarakt-OP ohne zusätzliches Risiko einsetzbar.
Comparison of Outcomes of External Dacryocystorhinostomy and Transcanalicular Laser-Assisted Dacryocystorhinostomy in Patients with Primary Acquired Nasolacrimal Duct Obstruction
Authors: Mutlu Demet , Bayram Nurettin , Arici Mustafa Kemal , Ozec Ayse Vural , Erdogan Haydar , Toker Mustafa Ilker 
Published: February 2022

AbstractPurpose This study aimed to compare anatomical and functional outcomes of external dacryocystorhinostomy (EX-DCR) and transcanalicular multidiode laser dacryocystorhinostomy (TDL-DCR) in patients with primary acquired nasolacrimal duct obstruction (PANDO).Methods This study was conducted on 60 eyes of 60 patients with PANDO. The study subjects were randomly divided into two groups. Group 1 included 30 patients who underwent EX-DCR, and group 2 included 30 patients who underwent TDL-DCR. Surgery success rates were determined by patency of the neo-ostium, with free saline flow on irrigation and the absence of epiphora.Results There were 23 women (76.7%) and 7 men (23.3%) with a mean age of 47.33 ± 12.44 years in group 1, and 18 women (60%) and 12 men (40%) with a mean age of 46.2 ± 19.4 years in group 2. There was no significant difference between groups 1 and 2 with respect to age or gender (p = 0.801, p = 0.267, respectively). The mean duration of symptoms was 3.2 years, ranging from 1.5 to 5 years. The mean postoperative follow-up was 12.3 ± 2.44 months. At the end of the follow-up period, the surgery success rates were 96.7% (29/30 eyes) in group 1, and 90% (27/30 eyes) in group 2. There was no statistical difference in the surgery success rates between groups (p = 0.612).Conclusion TDL-DCR is a minimally invasive and safe procedure. The lack of bleeding and incision scar and shorter operation time suggest that TDL-DCR can be a good alternative in PANDO patients.
Screening of Antimicrobial Activity of Essential Oils against Bovine Respiratory Pathogens – Focusing on Pasteurella multocida
Authors: Bismarck Doris , Becker Jens , Müller Elisabeth , Becher Vera , Nau Lisa , Mayer Philipp 
Published: February 2022

AbstractAdministration of essential oils as natural plant products with antimicrobial activity might be an alternative to antibiotic treatment of bovine respiratory disease. The aim of this study
was to analyse the in vitro antimicrobial activity of 11 essential oils against Pasteurella multocida isolated from the respiratory tract of calves using microdilution with
determination of minimum inhibitory and bactericidal concentration as well as agar disc diffusion. Additionally, antimicrobial activity against Mannheimia haemolytica and bacteria in
the Mannheimia clade was assessed by agar disc diffusion. Seven essential oil mixtures were also tested against all bacterial isolates. P. multocida was strongly inhibited by
cinnamon cassia and lemongrass oil followed by coriander, winter savory, thyme, clove, and peppermint oil in the microdilution assays. Eucalyptus, wintergreen, spruce, and star anise oil
showed lower activity. Comparison of both methods revealed an underestimation of cinnamon cassia oil activity by agar disc diffusion and conflicting results for wintergreen oil in
microdilution, which precipitated in broth. Cinnamon cassia, thyme, wintergreen, lemongrass, and winter savory oil all showed strong antimicrobial activity against M. haemolytica.
Bacteria in the Mannheimia clade were mostly inhibited by cinnamon cassia and thyme oil. Pasteurella isolates were more susceptible to inhibition by essential oils than
Mannheimia isolates. Essential oil mixtures did not show stronger antibacterial activity than single essential oils. In conclusion, cinnamon cassia and lemongrass as well as
coriander, winter savory, and thyme oil are promising candidates for treatment of P. multocida-associated bovine respiratory infections.
Stationäre Behandlung exklusiv zur Raucherentwöhnung – Konzept einer intensivierten verhaltenstherapeutischen Gruppentherapie
Authors: Dickreuter Jonas , Jähne Andreas , Leifert Jens A. 
Published: February 2022

ZusammenfassungZielsetzung Angesichts hoher Morbidität und Mortalität durch Tabakabhängigkeit besteht ein dringender Bedarf an effektiven Angeboten zur Raucherentwöhnung. Die leitliniengemäß durchgeführten ambulanten Therapien sind in ihrer langfristigen Wirksamkeit jedoch limitiert. Im Folgenden wird ein erstmalig in Deutschland entwickeltes wissenschaftliches stationäres Therapiekonzept ausschließlich zur stationären Raucherentwöhnung beschrieben und die Evidenz für die langfristige Effektivität dieser intensivierten Therapieform zur Raucherentwöhnung diskutiert.Methodik Es handelt es sich um ein multimodales neuntägiges verhaltenstherapeutisches Therapiekonzept für den stationären Einsatz. Die Entwöhnung wird als Gruppentherapie leitliniengemäß von einem mobil einsetzbaren Team geschulter Raucherentwöhner:innen durchgeführt, ergänzt durch Angebote zur Förderung der Gruppenkohäsion, Tagesstrukturierung, zum Bewegungstraining, Ernährungsmanagement, Ressourcenaufbau, Expositionstraining rückfallkritischer Situationen und zur achtsamkeitsbasierten Stressbewältigung.Schlussfolgerungen Eine stationäre Raucherentwöhnungstherapie ist als vielversprechende Ergänzung bzw. Alternative zur ambulanten Entwöhnung umsetzbar. Die intrinsische Abstinenzmotivation soll in einem geschützten Rahmen bei professioneller Betreuung und Unterstützung in der Gruppe gestärkt werden mit Fokus auf den Transfer der Kompetenzen in den Alltag. Erste Studienergebnisse weisen auf eine hohe langfristige Entwöhnungsquote hin. Eine wissenschaftliche Überprüfung der (Kosten-)Effektivität anhand randomisiert-kontrollierter Studien steht noch aus.
Early Initiation and Long-Term Use of Vaginal Progesterone may Cause
Gestational Diabetes Mellitus
Authors: Oztekin Deniz , Senkaya Ayse Rabia , Gunes Mehmet Emin , Keskin Omur , Dogdu Irmak Atci 
Published: February 2022

Abstract
Background Preterm birth (PTB) is an important cause of neonatal mortality
and morbidity. Spontaneous PTB (sPTB) is the most common cause of PTB. In
patients with a singleton pregnancy, progesterone treatment appears to reduce
the rate of spontaneous preterm birth in those with a previous history of
spontaneous preterm labor and/or cervical shortening in the current
pregnancy. Progesterone therapies used for the prevention of sPTB may increase
the risk of gestational diabetes mellitus (GDM) towards the end of pregnancy
owing to their effects on carbohydrate metabolism.
Aim We aimed to show the effects of vaginal progesterone use, starting
time, and duration of treatment on GDM.
Methods A retrospective cohort study was carried out in pregnant women 18
to 39 years old who came to our hospital between January 1, 2021, and August 31,
2021, and who had a 2-hour 75-g oral glucose tolerance test (OGTT) at 24 to 28
weeks of gestation. In a total of 540 patients, 68 were diagnosed with GDM based
on at least one abnormal plasma glucose value at screening. The remaining 472
patients with normal plasma glucose levels were considered as the control group.
The groups were compared in terms of age, parity, pre-pregnancy body mass index
(BMI), smoking, gestational age, and vaginal progesterone use. Patients using
vaginal progesterone with and without GDM were then compared again in terms of
indications for vaginal progesterone use, initiation time of progesterone
therapy, duration of progesterone use, and cervical length.
Results The incidence of GDM in our study group was 12.5%. Despite
the use of vaginal progesterone at a higher rate in the GDM group than in the
control group (23.5 vs. 13.9%; p=0.07), it was not statistically
significant. When we examined patients using progesterone as a subgroup
analysis, the mean time to start vaginal progesterone treatment was
19.8±2.6 (14–24), and it was significantly earlier in the GDM
group (18.1±2.0 vs. 20.2±2.6; p=0.007). Initiation of
vaginal progesterone before 20 weeks of gestation was statistically
significantly more frequent in the GDM group than the control group (68.8 vs.
39.4%; p=0.050 OR :3.3, 95%CI: 1.0–10.8). The
mean duration of vaginal progesterone use was 50.0±15.6 days
(28–90) and it was longer in the GDM group (57.8±13.4 vs.
48.1±15.6; p=0.027).
Conclusion Since the duration of vaginal progesterone use will be
prolonged, there may be a risk of GDM, especially in patients who started
vaginal progesterone before the 20th week of pregnancy. Even if the OGTT test
performed between 24–28 weeks is normal, it should be kept in mind that
these patients may have GDM in the later weeks of pregnancy, and repeating the
OGTT test should be considered if necessary.
COVID-19 Lockdown Periods in 2020: Good Maintenance of Metabolic
Control in Adults with Type 1 and Type 2 Diabetes
Authors: Hartmann B , Tittel S R , Femerling M , Pfeifer M. , Meyhöfer S. , Lange K , Milek S , Stemler L , Best F , Holl R W 
Published: February 2022

AbstractDuring the COVID-19 pandemic, there were increased concerns about glycemic
control in patients with diabetes. Therefore, we aimed to assess changes in
diabetes management during the COVID-19 lockdown for patients with type 1 or
type 2 diabetes mellitus (T1DM, T2DM) in Germany. We included data from 24,623
patients (age>18 years) with T1DM (N=6,975) or T2DM
(N=17,648) with documented data in 2019 and 2020 from the multicenter
Diabetes-Prospective Follow-up registry (DPV). We conducted a groupwise
comparison of identical patients in 2019 and 2020 for different time periods of
pandemia. Pairwise differences of continuous parameters of treatment modalities
and metabolic outcome between 2019 and 2020 were adjusted for seasonality, age,
and diabetes duration. We presented these outcomes as adjusted medians with
95% confidence intervals. Rates were compared using negative-binomial
models, dichotomous outcomes were compared using logistic models. Models were
additionally adjusted for age and diabetes duration. These outcomes were
presented as least-square means with 95% confidence intervals, p-values
of<.05 were considered significant.In participants with T1DM, CGI (combined glucose indicator) increased only by
0.11–0.12% in all time periods of 2020 compared to 2019 (all
p<0.001) while BMI decreased slightly by −(0.09–0.10)
kg/m² (p<0.0001). In participants with T2DM, HbA1c
increased by 0.12%, while BMI decreased slightly by
−(0.05–0.06) kg/m² (p<0.0001).During the COVID-19 lockdown period, patients with T1DM and T2DM experienced only
clinically insignificant changes in glucose control or body weight. Despite
lockdown restrictions, patients were able to maintain metabolic control.
Impact of transmural plastic stent on recurrence of pancreatic fluid collection after metal stent removal in disconnected pancreatic duct: a randomized controlled trial
Authors: Chavan Radhika , Nabi Zaheer , Lakhtakia Sundeep , Gupta Rajesh , Jahangeer Basha , Talukdar Rupjyoti , Singh Aniruddha Pratap , Karyampudi Arun , Yarlagadda Raghavendra , Ramchandani Mohan , Kalapala Rakesh , Jagtap Nitin , Reddy Manohar , Tandan Manu , Rao Guduru Venkat , Reddy Nageshwar D. 
Published: February 2022

Background Disconnected pancreatic duct (DPD) after development of walled-off necrosis (WON) predisposes to recurrent (peri)pancreatic fluid collection (PFC). In this randomized controlled trial, we compared plastic stents with no plastic stent after removal of a large-caliber metal stent (LCMS) on incidence of recurrent PFCs in DPD.
Methods Consecutive patients with WON who underwent endoscopic ultrasound (EUS)-guided drainage with LCMS between September 2017 and March 2020 were screened for eligibility. At LCMS removal (4 weeks after drainage), patients with DPD were randomized to plastic stent or no stent groups. The primary outcome was incidence of recurrent PFC at 3 months. Secondary outcomes were technical success of plastic stent deployment, adverse events, stent migration, and recurrence of PFC at 6 and 12 months.
Results 236 patients with WON underwent EUS-guided drainage using LCMS, and 104 (males 94, median age 34 years (interquartile range [IQR] 26–44.7) with DPD were randomized into stenting (n = 52) and no-stenting (n = 52) groups. Plastic stent deployment was successful in 88.5 %. Migration occurred in 19.2 % at median follow-up of 8 months (IQR 2.5–12). Recurrent PFCs occurred in six patients at 3 months (stent n = 3, no stent n = 3). There was no significant difference in PFC recurrence between the two groups at 3, 6, and 12 months. Reintervention was required in seven patients with recurrent PFCs, with no significant difference between the two groups.
Conclusion In patients with WON and DPD, deployment of plastic stents after LCMS removal did not reduce recurrence of PFC.
Serum Vasostatin-1 Level is Increased in Women with
Preeclampsia
Authors: Tüten Abdullah , Tüten Nevin , Gök Koray , Hamzaoglu Kubra , Bulut Huri , Malik Eduard , Guralp Onur 
Published: February 2022

Abstract
Objective To evaluate the serum vasostatin-1 levels in preeclamptic and
non-preeclamptic pregnant women.
Materials and methods Thirty consecutive women with mild preeclampsia and
sixty consecutive women with severe preeclampsia were compared with ninety
gestational age-matched (±1 week) non-preeclamptic pregnant women with
an appropriate-for-gestational-age (AGA) fetus.
Results Mean serum vasostatin-1 was significantly higher in women with
preeclampsia than gestational age-matched controls. Mean serum vasostatin-1 was
significantly higher in the mild preeclampsia group compared to its gestational
age-matched control group, and in the severe preeclampsia group compared to its
gestational age-matched control group. There was no significant difference in
mean serum vasostatin-1 levels between the mild and severe preeclampsia groups,
and in severe early- and severe late-onset preeclampsia groups. Serum
vasostatin-1 had positive correlations with systolic and diastolic blood
pressure.
Conclusion Serum vasostatin-1 was significantly higher in women with
preeclampsia compared to those of the gestational age-matched controls. There
was no significant difference in mean serum vasostatin-1 levels between the mild
and severe preeclampsia groups and severe early- and severe late-onset
preeclampsia groups.
Complementary Photocatalytic Toolbox: Control of Intramolecular endo- versus exo-trig Cyclizations of α-Phenyl Olefins to Oxaheterocyclic Products
Authors: Wagenknecht Hans-Achim , Weick Fabian , Steuernagel Desirée , Belov Arina 
Published: February 2022

AbstractThe regioselectivity of the intramolecular cyclization of bifunctional α-phenyl alkenes can be controlled simply by the choice of the organic chromophore as the photocatalyst. The central photoredox catalytic reaction in both cases is a nucleophilic addition of the hydroxy function to the olefin function of the substrates. N,N-(4-Diisobutylaminophenyl)phenothiazine catalyzes exo-trig cyclizations, whereas 1,7-dicyanoperylene-3,4,9,10-tetracarboxylic acid bisimides catalyze endo-trig additions to products with anti-Markovnikov regioselectivity. We preliminarily report the photoredox catalytic conversions of 11 representative substrates into 20 oxaheterocycles in order to demonstrate the similarity, but also the complementarity, of these two variants in this photoredox catalytic toolbox.
Effectiveness of a Uniquely Designed Oral Appliance on Obstructive Sleep Apnea Control: A Pilot Study
Authors: Barbosa Denise Fernandes , Meira e Cruz Miguel , Alves Marcelo Corrêa , Zancanella Edilson , Berzin Fausto , Júnior Almiro José Machado 
Published: February 2022

Abstract
Objectives Obstructive sleep apnea is an inflammatory, chronic, and evolutive disease often needing adequate treatment and follow-up. The oral appliance (OA) is an accepted alternative therapy for obstructive sleep apnea (OSA) control. Due to greater adherence, OA with mandibular advancement (OAm) is being recommended treatment for patients who refuse or do not tolerate continuous positive airway pressure. The mode of action of OAm is to promote the advancement of the mandible or tongue with a subsequent increase in the tone of the pharyngeal muscles and the permeability of the upper airway, but most OAm use conventional models as reference, analogic, or digital, dissociating dental arches of the skull structures.
Materials and Methods A retrospective longitudinal study of 33 OSA patient treated with a different OAm, that use Camper plane as reference with skull structures for dental arches disocclusion, where polysomnographic, cephalometric measures, and subjective data from questionnaires pre- and post-treatment were assessed and correlated. Descriptive analysis, correlated Chi-square tests, and basic statistics were used. Generalized linear mixed model for repeated measure and post hoc Tukey–Kramer test compares the variables pre- and post-treatment. Shapiro–Wilk test and Pearson's correlation coefficients were used. All statistical tests were set in 5% level of significance.
Results Regarding polysomnography data, there was a significant association between apnea hypopnea index (AHI) with oxygen saturation, arousal index (AI) and the maximum heartbeats, and sleep improvement and health risk reduction. Additionally, from cephalometric data, it was found a significant association between the tongue posture with the soft palate, hioyd-C3 and, lower and posterior airway. When both parameters are correlated, there are a significant dependent association with hyoid bone position with AHI and AI. The limitation of this study was the two-dimensional image used without provide volumetric measurements, but this limitation was reduced with the follow-up polysomnography parameters.
Conclusion In this pilot study, DIORS OAm as an uniquely designed device using Camper plane as a reference for disocclusion was effective in the control of OSA.