bluuebunny/crossref_metadata_2025_split huggingface dataset:
Substituting bouts of sedentary behavior with physical activity: adopting positive lifestyle choices in people with a history of cancer
Authors: Ingle Lee , Ruilova Samantha , Cui Yunsung , DeClercq Vanessa , Sweeney Ellen , Yu Zhijie Michael , Forbes Cynthia C. 
Published: June 2022

Abstract
Purpose
To determine in people with a history of cancer, whether substituting sitting time with other daily activities (i.e., sleeping, walking, moderate and vigorous physical activity) was associated with changes in waist circumference (WC), an important surrogate marker of cardiometabolic risk.

Methods
Cross-sectional analyses from the Atlantic Partnership for Tomorrow’s Health (Atlantic PATH) cohort was conducted using isotemporal substitution models to explore the associations of substituting sedentary time, physical activity behavior (International Physical Activity Questionnaire), or sleep (Pittsburgh Sleep Quality Index) with changes in WC. Analyses were conducted using sex-specific WC classifications.

Results
In 3,684 people with a history of cancer [mean age (SD) 58.2 (7.3) years; BMI 28.9 (5.2) kg m−2; 71% female], reallocating 10 min of sleep or sedentary time for 10 min of walking was associated with lower WC in women (p < 0.01). In men, PA intensity appeared to be more strongly associated with a reduced WC. Replacing 10 min of sedentary time with 10 min of moderate or vigorous PA and replacing 10 min of sleep with moderate PA were associated with a significantly reduced WC (p < 0.001). The largest effect was when 10 min of moderate PA was replaced with vigorous PA, a reduction in WC (p < 0.01) was evident.

Conclusion
For people with a history of cancer, adopting small but positive changes in lifestyle behaviors could help reduce WC and potentially offset negative health-related outcomes associated with higher WC. Further research is required to examine whether such an intervention may be acceptable and manageable among this population.
Evidence for Protective Effects of Peer Play in the Early Years: Better Peer Play Ability at Age 3 Years Predicts Lower Risks of Externalising and Internalising Problems at Age 7 Years in a Longitudinal Cohort Analysis
Authors: Zhao Yiran Vicky , Gibson Jenny Louise 
Published: June 2022

AbstractPeer play ability may be a protective factor against childhood mental health difficulties but there is lack of empirical evidence to support this hypothesis. We conducted longitudinal structural equation modelling study over a population cohort (N = 1676) to examine the effect of age 3 peer play ability on children’s age 7 mental health outcomes (measured by the Strengths and Difficulties Questionnaire subscales). We modelled effects for the entire population and two sub-groups at high-risk for mental health problems based on age 3 temperament. Controlling for demographic variables, temperament, maternal distress, play with parents and number of siblings, better peer play ability at age 3 years predicted lower risk of problems on all 4 SDQ subscales at age 7 years for the general population. For the low-persistence subgroup, better peer play ability at age 3 predicted lower risk of age 7 hyperactivity, emotional and peer problems, whereas better peer play ability at age 3 predicted only lower risk of age 7 hyperactivity for the high-reactivity group. Taken together our results provide evidence that supports the hypothesis that early peer play ability may be a protective factor against later mental health difficulties. We conclude that further research aimed at establishing causation is worth pursuing.
A Ribbon Model for Nematic Polymer Networks
Authors: Singh Harmeet , Virga Epifanio G. 
Published: June 2022

AbstractWe present a theory of deformation of ribbons made of nematic polymer networks (NPNs). These materials exhibit properties of rubber and nematic liquid crystals, and can be activated by external stimuli of heat and light. A two-dimensional energy for a sheet of such a material has already been derived from the celebrated neo-classical energy of nematic elastomers in three space dimensions. Here, we use a dimension reduction method to obtain the appropriate energy for a ribbon from the aforementioned sheet energy. We also present an illustrative example of a rectangular NPN ribbon that undergoes in-plane serpentine deformations upon activation under an appropriate set of boundary conditions.
Information Asymmetry in Business-to-Business Negotiations: A Game Theoretical Approach to Support Purchasing Decisions with Suppliers
Authors: Bodendorf Frank , Hollweck Barbara , Franke Jörg 
Published: June 2022

AbstractThe digital transformation confronts purchasing and supply management (PSM) with numerous new challenges, such as digital procurement objects and the information asymmetry between buyers and suppliers. Existing approaches contributing to PSM research (e. g., the selection of suppliers or the calculation of equilibrium prices) have in common that information regarding suppliers (e. g., production costs) must be well-known. However, this information is rarely accessible to purchasers due to the existing information asymmetry. This problem is addressed by a game-theoretical model based on a Stackelberg game to assist PSM in dealing with the information advantage of software suppliers. The applicability in practice is evaluated by a real-world case study from the automotive industry. The results show that the presented model can support decision-making in purchasing by a qualitative analysis of profit scenarios for different negotiation strategies. The model contributes to dismantling the information asymmetry and provides a basis for determining negotiation prices, also for digital procurement objects. This research motivates both supply and purchase managers to jointly optimize their product costs and thus increase their competitiveness on the market.
Image Reconstruction in Light-Sheet Microscopy: Spatially Varying Deconvolution and Mixed Noise
Authors: Toader Bogdan , Boulanger Jérôme , Korolev Yury , Lenz Martin O. , Manton James , Schönlieb Carola-Bibiane , Mureşan Leila 
Published: June 2022

AbstractWe study the problem of deconvolution for light-sheet microscopy, where the data is corrupted by spatially varying blur and a combination of Poisson and Gaussian noise. The spatial variation of the point spread function of a light-sheet microscope is determined by the interaction between the excitation sheet and the detection objective PSF. We introduce a model of the image formation process that incorporates this interaction and we formulate a variational model that accounts for the combination of Poisson and Gaussian noise through a data fidelity term consisting of the infimal convolution of the single noise fidelities, first introduced in L. Calatroni et al. (SIAM J Imaging Sci 10(3):1196–1233, 2017). We establish convergence rates and a discrepancy principle for the infimal convolution fidelity and the inverse problem is solved by applying the primal–dual hybrid gradient (PDHG) algorithm in a novel way. Numerical experiments performed on simulated and real data show superior reconstruction results in comparison with other methods.
An Immunological Axis Involving Interleukin 1β and Leucine-Rich-α2-Glycoprotein Reflects Therapeutic Response of Children with Kawasaki Disease: Implications from the KAWAKINRA Trial
Authors: Kessel Christoph , Koné-Paut Isabelle , Tellier Stéphanie , Belot Alexandre , Masjosthusmann Katja , Wittkowski Helmut , Fuehner Sabrina , Rossi-Semerano Linda , Dusser Perrine , Marie Isabelle , Boukhedouni Nadja , Agostini Helène , Piedvache Céline , Foell Dirk 
Published: June 2022

Abstract

Purpose
A recent phase II open-label study of the interleukin 1 (IL-1) receptor antagonist (IL-1Ra) anakinra in treating IVIG-resistant Kawasaki disease (KD) patients reported promising results. Here, we aimed to characterize the immunological impact of IL-1 blockade in this unique study population.

Methods
Patients’ and control sera and supernatants of cells (whole blood, neutrophils, coronary artery endothelial cells) stimulated with recombinant IL-1β were analyzed for single or multiple marker (n = 22) expression by ELISA or multiplexed bead array assay. Data were analyzed using unsupervised hierarchical clustering, multiple correlation, and multi-comparison statistics and were compared to retrospective analyses of KD transcriptomics.

Results
Inflammation in IVIG-resistant KD (n = 16) is hallmarked by over-expression of innate immune mediators (particularly IL-6 > CXCL10 > S100A12 > IL-1Ra). Those as well as levels of immune or endothelial cell activation markers (sICAM-1, sVCAM-1) declined most significantly in course of anakinra treatment. Prior as well as following IL-1R blockade, over-expression of leucine-rich-α2-glycoprotein 1 (LRG1) associated best with remnant inflammatory activity and the necessity to escalate anakinra dosage and separated inflammatory KD patients from sJIA-MAS (n = 13) and MIS-C (n = 4). Protein as well as retrospective gene expression analyses indicated tight association of LRG1 with IL-1β signaling and neutrophilia, while particularly neutrophil stimulation with recombinant IL-1β resulted in concentration-dependent LRG1 release.

Conclusion
Our study identifies LRG1 as known trigger of endothelial activation and cardiac re-modeling to associate with IL-1β signaling in KD. Besides a potential patho-mechanistic implication of these findings, our data suggest blood leukocyte and neutrophil counts to best predict response to IL-1Ra treatment in IVIG-resistant KD.
Optimising Foil Selection for Neutron Activation Systems
Authors: Wong O. , Smith R. , Nobs C. R. , Bruce A. M. 
Published: June 2022

AbstractNeutron spectrum unfolding using activation foils is currently the primary technique planned for measuring the neutron energy spectrum at the first wall of power-generating fusion reactors. Room for improvement in the effectiveness of current foil selection was identified, and a program produced to select foils procedurally in order to maximise the accuracy of the unfolding procedure. Using Kullback–Leibler Divergence to quantify the accuracy, the spectrum unfolded by the procedurally selected set of foils is found to be more accurate than the spectrum unfolded by a set of foils used in the literature.
The Large Deviation Principle for Inhomogeneous Erdős–Rényi Random Graphs
Authors: Markering Maarten 
Published: June 2022

AbstractConsider the inhomogeneous Erdős-Rényi random graph (ERRG) on n vertices for which each pair $$i,j\in \{1,\ldots ,n\}$$

i
,
j
∈
{
1
,
…
,
n
}

, $$i\ne j,$$

i
≠
j
,

is connected independently by an edge with probability $$r_n(\frac{i-1}{n},\frac{j-1}{n})$$

r
n

(

i
-
1

n

,

j
-
1

n

)

, where $$(r_n)_{n\in \mathbb {N}}$$

(

r
n

)

n
∈
N

is a sequence of graphons converging to a reference graphonr. As a generalisation of the celebrated large deviation principle (LDP) for ERRGs by Chatterjee and Varadhan (Eur J Comb 32:1000–1017, 2011), Dhara and Sen (Large deviation for uniform graphs with given degrees, 2020. arXiv:1904.07666) proved an LDP for a sequence of such graphs under the assumption that r is bounded away from 0 and 1, and with a rate function in the form of a lower semi-continuous envelope. We further extend the results by Dhara and Sen. We relax the conditions on the reference graphon to $$(\log r, \log (1- r))\in L^1([0,1]^2)$$

(
log
r
,
log

(
1
-
r
)

)

∈

L
1

(

[
0
,
1
]

2

)

. We also show that, under this condition, their rate function equals a different, more tractable rate function. We then apply these results to the large deviation principle for the largest eigenvalue of inhomogeneous ERRGs and weaken the conditions for part of the analysis of the rate function by Chakrabarty et al. (Large deviation principle for the maximal eigenvalue of inhomogeneous Erdoös-Rényi random graphs, 2020. arXiv:2008.08367).
A Comparison of the Oxidation and Nitridation Properties of Selected Chromia- and Alumina-Forming Alloys at 800 °C
Authors: Sand T. , Liske J. , Helander T. , Svensson J.-E. , Johansson L.-G. 
Published: June 2022

AbstractThree FeCrAl alloys and two chromia-formers (a stainless steel, and a Ni-base alloy) have been exposed in four environments (dry air, air + 20% H2O, 20% H2 + 20% H2O + Ar and 95% N2 + 5% H2) for 168 h at 800 °C. The corroded samples were investigated by SEM/EDS, XRD and gravimetry, and the formation of CrO2(OH)2(g) was measured as a function of time using a denuder technique. The Fe-base alloy formed a Cr-rich protective oxide scale in dry air and wet air but suffered break-away oxidation in 20% H2 + 20% H2O + Ar. In contrast, the Ni-base alloy suffered extensive NiO formation and internal oxidation in dry air and wet air but formed a protective chromia scale in 20% H2 + 20% H2O. All three FeCrAl alloys formed protective alumina scales in dry air, wet air and 20% H2 + 20% H2O + Ar. The FeCrAl alloy Kanthal APMT was severely nitrided in the 95% N2 + 5% H2 environment due to defects in the oxide scale associated with RE-rich inclusions which allowed nitrogen to enter the alloy. In contrast, the two Cr-lean FeCrAl alloys Kanthal EF101 and Kanthal EF100 did not suffer nitridation at all.
Mortality and morbidity in ageing men: Biology, Lifestyle and Environment
Authors: Zhao Erfei , Crimmins Eileen M. 
Published: June 2022

AbstractMales live shorter lives than women in all countries. The universality of shorter male life expectancy is a 21st Century phenomena. It occurs with the decline in infectious diseases and the rise in cardiovascular diseases accounting for mortality. Male/female differences in morbidity are not as succinctly characterized. Men have a higher prevalence of lethal diseases, which is linked to their lower life expectancy. Women have more non-lethal conditions such as depression and arthritis; which may also be linked in part to longer survival. Men have better physical functioning and less disability which is partly explained by gender differences in diseases and also by their greater strength, size, and stamina. Gender differences in risk factors for disease have changed over time with the prevalence and treatment of risk as well as differential behavior by gender. Examination of what are seen as basic molecular and cellular measures related to aging indicates men age faster than women; however, even these basic biological measures result from a combination of biology, behavior, and social factors.
High-intensity interval training modulates inflammatory response in Parkinson’s disease
Authors: Malczynska-Sims Paulina , Chalimoniuk Małgorzata , Wronski Zbigniew , Marusiak Jaroslaw , Sulek Anna 
Published: June 2022

Abstract
Background
Recent discoveries show that high-intensity interval training (HIIT) can bring many positive effects such as decreases in fat tissue, lower blood sugar levels, improved learning and memory, and lower risk of cardiac disease. Parkinson’s disease (PD) is a neurodegenerative disorder characterized by loss of the dopaminergic neurons, accompanied by chronic inflammation and neuroinflammation. Previous research shows that interval training can bring a beneficial effect on the inflammation and neuroplasticity in PD.

Objectives
The objective of this study was to investigate the effect of 12 weeks of HIIT on the inflammation levels and antioxidant capacity in the serum of PD patients.

Methods
Twenty-eight people diagnosed with PD were enrolled in this study. Fifteen PD patients performed 12 weeks of HIIT on a cycloergometer. Thirteen non-exercised PD patients constitute the control group. Concentrations of inflammation markers and antioxidants’ capacity in the serum were measured at 3 sampling points (a week before, a week after, and 3 months after the HIIT).

Results
Twelve weeks of HIIT decreases the level of TNF-α (p = 0.034) and increases the level of IL-10 (p = 0.024). Those changes were accompanied by a decreased level of neutrophils (p = 0.03), neutrophil/lymphocyte ratio (p = 0.048) and neutrophil/monocyte ratio (p = 0.0049) with increases in superoxide dismutase levels (p = 0.04).

Conclusions
Twelve weeks of HIIT can decrease systemic inflammation in PD patients and improve the antioxidant capacity in their serum, which can slow down the progression of the disease.
The Striatus bridge
Authors: Bhooshan Shajay , Bhooshan Vishu , Dell’Endice Alessandro , Chu Jianfei , Singer Philip , Megens Johannes , Van Mele Tom , Block Philippe 
Published: June 2022

AbstractThe paper describes the physical realisation of a 3D-concrete-printed, mortar-free, unreinforced masonry arched footbridge, designed for disassembly and reuse. The paper also details the novel integrated design, engineering and fabrication framework and the manufacturing and assembly processes used for the project. The research, motivated by the rapid growth in large-scale 3D concrete printing (3DCP), addresses the current lack of both design tools and integrated design-to-production solutions. It is guided by the insight regarding the applicability of design and analysis methods used in unreinforced masonry to large-scale, layered 3D printing with compression dominant materials such as concrete. Thus, the underlying computational framework and integrated design environment further extends and adapts advances in the computational design and analysis of unreinforced masonry structures to 3DCP masonry blocks. Adopting an unreinforced masonry paradigm for the design of 3DCP structures can make it possible to (i) reduce the amount of concrete used by allowing precise placement of concrete only where needed along the compressive flow of forces, (ii) reduce the amount of steel needed by reducing tensile and flexural strength requirements through a compression-appropriate design of both the global, shape and the block discretisation, and (iii) reuse components, repair the structures and recycle materials more easily. This paper builds on the relevance of the computational masonry paradigm to both delivering the ecological promises of 3DCP and to the development of a 3DCP-specific, design-to-production toolkit.
Weighted Bayesian Poisson Regression for The Number of Children Ever Born per Woman in Bangladesh
Authors: Tomal Jabed H. , Khan Jahidur Rahman , Wahed Abdus S. 
Published: June 2022

AbstractNumber of children ever born to women of reproductive age forms a core component of fertility and is vital to the population dynamics in any country. Using Bangladesh Multiple Indicator Cluster Survey 2019 data, we fitted a novel weighted Bayesian Poisson regression model to identify multi-level individual, household, regional and societal factors of the number of children ever born among married women of reproductive age in Bangladesh. We explored the robustness of our results using multiple prior distributions, and presented the Metropolis algorithm for posterior realizations. The method is compared with regular Bayesian Poisson regression model using a Weighted Bayesian Information Criterion. Factors identified emphasize the need to revisit and strengthen the existing fertility-reduction programs and policies in Bangladesh.
Corrigendum: Liftings of Jordan and Super Jordan Planes
Authors: Andruskiewitsch Nicolás , Angiono Iván , Heckenberger István 
Published: June 2022

AbstractWe complete the classification of the pointed Hopf algebras with finite Gelfand-Kirillov dimension that are liftings of the Jordan plane over a nilpotent-by-finite group, correcting the statement in [N. Andruskiewitsch, I. Angiono and I. Heckenberger, Liftings of Jordan and super Jordan planes, Proc. Edinb. Math. Soc., II. Ser. 61(3) (2018), 661–672.].
Prevalence of trypanosomes and selected symbionts in tsetse species of eastern Zambia
Authors: Mulenga Gloria M. , Namangala Boniface , Gummow Bruce 
Published: June 2022

AbstractInsect symbionts have attracted attention for their potential use as anti-parasitic gene products in arthropod disease vectors. While tsetse species of the Luangwa valley have been extensively studied, less is known about the prevalence of symbionts and their interactions with the trypanosome parasite. Polymerase chain reaction was used to investigate the presence of Wolbachia and Sodalis bacteria, in tsetse flies infected with trypanosomes (Trypanosoma vivax, Trypanosoma congolense and Trypanosoma brucei). Out of 278 captured tsetse flies in eastern Zambia, 95.3% (n = 265, 95% CI = 92.8–97.8) carried endosymbionts: Wolbachia (79.1%, 95% CI 73.9–83.8) and Sodalis (86.3%, 95% CI 81.7–90.1). Overall, trypanosome prevalence was 25.5% (n = 71, 95% CI = 20.4–30.7), 10.8% (n = 30, 95% CI 7.1–14.4) for T. brucei, 1.4% (n = 4, 95% CI = 0.4–3.6) for both T. congolense and T. vivax, and 0.7% (n = 2, 95% CI 0.1–2.6) for T. b. rhodesiense. Out of 240 tsetse flies that were infected with Sodalis, trypanosome infection was reported in 40 tsetse flies (16.7%, 95% CI = 12.0–21.4) while 37 (16.8%, 95% CI 11.9–21.8) of the 220 Wolbachia infected tsetse flies were infected with trypanosomes. There was 1.3 times likelihood of T. brucei infection to be present when Wolbachia was present and 1.7 likelihood of T. brucei infection when Sodalis was present. Overall findings suggest absence of correlation between the presence of tsetse endosymbionts and tsetse with trypanosome infection. Lastly, the presence of pathogenic trypanosomes in tsetse species examined provided insights into the risk communities face, and the importance of African trypanosomiasis in the area.
Cognitive bias modification for paranoia (CBM-pa): a randomised controlled feasibility study in patients with distressing paranoid beliefs
Authors: Yiend Jenny , Lam Charlene L. M. , Schmidt Nora , Crane Bryony , Heslin Margaret , Kabir Thomas , McGuire Philip , Meek Christopher , Mouchlianitis Elias , Peters Emmanuelle , Stahl Daniel , Trotta Antonella , Shergill Sukhwinder 
Published: June 2022

AbstractBackgroundCognitive Bias Modification for paranoia (CBM-pa) is a novel, theory-driven psychological intervention targeting the biased interpretation of emotional ambiguity associated with paranoia. Study objectives were (i) test the intervention's feasibility, (ii) provide effect size estimates, (iii) assess dose–response and (iv) select primary outcomes for future trials.MethodsIn a double-blind randomised controlled trial, sixty-three outpatients with clinically significant paranoia were randomised to either CBM-pa or an active control (text reading) between April 2016 and September 2017. Patients received one 40 min session per week for 6 weeks. Assessments were given at baseline, after each interim session, post-treatment, and at 1- and 3-months post-treatment.ResultsA total of 122 patients were screened and 63 were randomised. The recruitment rate was 51.2%, with few dropouts (four out of 63) and follow-up rates were 90.5% (1-month) and 93.7% (3-months). Each session took 30–40 min to complete. There was no statistical evidence of harmful effects of the intervention. Preliminary data were consistent with efficacy of CBM-pa over text-reading control: patients randomised to the intervention, compared to control patients, reported reduced interpretation bias (d = −0.48 to −0.76), improved symptoms of paranoia (d = −0.19 to −0.38), and lower depressed and anxious mood (d = −0.03 to −0.29). The intervention effect was evident after the third session.ConclusionsCBM-pa is feasible for patients with paranoia. A fully powered randomised control trial is warranted.