bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minimum inertia demand estimation of new power system considering diverse inertial resources based on deep neural network
Authors: Zicheng Liu , Zhou Tao , Chen Zhong , Wang Yi , Wang Yalun 
Published: December 2022

AbstractWith the high‐proportion integration of renewable energy and power electronic equipment, the inertia supporting ability of new power system continues to decline, which seriously threatens the frequency stability of power grids. In order to clarify the operation boundary, and realise the rapid analysis and prediction of the minimum inertia demand of new power systems, this study proposes a minimum inertia demand estimation method based on deep neural network (DNN). Firstly, this study establishes the system frequency response model of new power systems containing diverse inertia resources including renewable energy, induction machine and so on. Considering the constraints of rate of change of frequency and maximum frequency deviation, the minimum inertia demand estimation model is established to ensure the system frequency stability. DNN is introduced to effectively map non‐linear relations in complex situations, which can quickly estimate and predict the minimum inertia of new power systems. Adam algorithm is utilised to optimise the input weight matrix and hidden layer feature vector of the network to improve accuracy. Finally, the simulations and analysis are conducted in IEEE‐39 system to verify the accuracy and generalisation ability of the proposed method in this paper.
Discharge characteristics of leader inception and development under 10 m long air gap—experimental observation and simulation results
Authors: Peng Changzhi , Dong Xuzhu , Zhao Yanpu , Li Zhijun , Zheng Yu , Pei Xuekai , Liu Lei , Luo Bing 
Published: December 2022

AbstractThe physical mechanism of leader formation and development is not well understood. In this study, we present experimental and simulation results obtained with a 10 m long air gap discharge. A 10 m outdoor discharge experiment is carried out to obtain the current, voltage, and optical image during the leader discharge process. Four different impulse voltages were applied to the rod‐plane gap. The measured current is used as an input for a plasma model, then the temperature and electric field could be calculated. The simulation results show that the temperature of the streamer stem during the dark period may exceed 2000 K. In addition, the critical charge required for leader initiation can be as low as 0.27 μC for a 10 m air gap. The channel temperature is relatively stable in the process of leader development, which is maintained at about 4500 K. The electron density is about 0.5–3 × 1020 m−3, and the discharge channel conductivity fluctuates in the range of 1–10 S/m for the leader current between 1 and 2 A. A long dark period is tended to be associated with a higher injected charge by the first streamer. It is inferred that the voltage increments during the dark period play an important role in promoting streamer‐to‐leader transition, except for temperature and the injected charge.
Geschlechtsspezifische sexuelle Gesundheitsförderung in geschlossenen Einrichtungen. Ein systematisches Review zum internationalen Forschungsstand
Authors: Kaplan Anne , Schneider Lisa , Scharnberg Madeline , Metzner Franka 
Published: December 2022

ZusammenfassungEinleitung Freiheitsentziehende Institutionen haben einen rechtlich normierten Auftrag zur sexuellen Gesundheitsförderung und Bildung. Maßnahmen zur sexuellen Gesundheitsförderung sollen gemäß der Ottawa-Charta der World Health Organization von 1986 ganzheitlich auf einem breiten und intersektionalen Verständnis von Sexualität und sexueller Gesundheit gründen. Nachgewiesene geschlechtsspezifische Unterschiede in der sexuellen Gesundheitskompetenz und im Sexualverhalten sollen darin berücksichtigt werden. Angebote sexueller Gesundheitsförderung in geschlossenen Einrichtungen sind bisher allerdings kaum dokumentiert.Forschungsziele In diesem Beitrag soll der internationale Forschungsstand zu geschlechtsspezifischer sexueller Gesundheitsförderung in geschlossenen, freiheitsentziehenden Einrichtungen zusammengefasst und diskutiert werden.Methoden Es wurde ein systematisches Literaturreview durchgeführt, um publizierte Konzepte und Studien zum genannten Themenspektrum zusammenzutragen. Dazu wurden sechs wissenschaftliche Datenbanken bis zum Stichtag 6. Oktober 2021 nach relevanten Publikationen auf Deutsch und Englisch durchsucht. Von k = 365 identifizierten Publikationen entsprachen k = 3 Studien nach der Bewertung durch zwei Reviewerinnen*1 allen 13 a priori festgelegten Einschlusskriterien (z. B. Publikation mit Peer-Review).Ergebnisse Festgestellt wurde ein großes Desiderat hinsichtlich evidenzbasierter Maßnahmen zur sexuellen Gesundheitsförderung in freiheitsentziehenden Einrichtungen. Es mangelt bei den wenigen, ausschließlich im nordamerikanischen Raum untersuchten Programmen an einem breiten Verständnis von Sexualität und sexueller Gesundheit. Die identifizierten Programme sind hauptsächlich auf einen Gefahren abwehrenden Sexualitätsbegriff gerichtet.Schlussfolgerung Menschen in Freiheitsentzug erscheinen von wissenschaftlichen und gesellschaftlichen Diskursen über Sexualität und sexuelle Gesundheit bisher weitgehend ausgeklammert zu sein. Evidenzbasierte Programme der sexuellen Gesundheitsförderung in geschlossenen Einrichtungen des Freiheitsentzuges sollten daher entwickelt und implementiert werden. Zentrale Themen wie (eigene) Geschlechtsidentitäten, Bindung und Partnerschaft oder Geschlechterrollen gilt es darin zu verhandeln und gemeinsam mit den Menschen in Freiheitsentzug kritisch zu reflektieren.
ω-3 und
Anti-Aging
Authors: Schmiedel Volker 
Published: December 2022

ZusammenfassungIn den letzten Jahrzehnten wurden viele Substanzen als Anti-Aging-Wundermittel
gehypt. Selten gab es jedoch belastbare Belege dafür, dass die
vollmundigen Versprechungen erfüllt werden konnte. Bei
ω-3-Fettsäuren (im Folgenden nur ω-3 genannt) scheint
dies anders zu sein, da mittlerweile eine Reihe von Studien und sogar
Metaanalysen existieren, die das Postulat einer lebensverlängernden und
jungerhaltenden Wirkung von ω-3 stützen.
Evaluation of the Morphometry of the Stylomastoid Foramen in the Turkish Population: A Retrospective Study Using Cone-Beam Computed Tomography (CBCT)
Authors: Yurdabakan Zeliha Zuhal , Okumuş Özlem , Orhan Kaan 
Published: December 2022

Abstract
Objectives This study aimed to investigate the morphometric features of the stylomastoid foramen (SMF) and the facial canal in the Turkish population using cone-beam computed tomography (CBCT) retrospectively.
Methods The randomly selected 479 patients aged from 8 to 87 years were examined, and a total of 958 CBCT images of the SMF and facial canal (FC) were analyzed. The diameter of the SMF and FC at the mastoid segment and their relation to age, gender, and side were evaluated. Statistical analyses were performed using Kolmogorov–Smirnov, one-way analysis of variance, Student's t-test, chi-squared test, Tukey's honestly significant difference, and Fisher-Freeman-Halton exact test. p-Values < 0.05 were accepted as statistically significant at the 95% confidence interval.
Results The mean age of the patients was 40.49 ± 19.73 years. The mean diameter of the right SMF was 2.24 ± 0.58 and 2.50 ± 0.63 mm in females and males. The mean diameter of the left SMF was 2.25 ± 0.56 and 2.44 ± 0.62 mm in females and males. The mean diameter of the right FC was 1.60 ± 0.35 and 1.70 ± 0.34 mm in females and males. The mean diameter of left FC was 1.55 ± 0.35 and 1.66 ± 0.33 mm in females and males. A statistically significant difference was found between the age groups in terms of the mean SMF and FC diameter on both sides (p < 0.05).
Conclusion Information obtained from this study regarding the morphometric features of the SMF and thereby FC may assist surgeons in treatment plans and reduce the risk of neurosurgical complications.
Is There a Plateau to the Learning Curve for Acoustic Neuroma Resection?—Experience and Outcomes from a Single Interdisciplinary Team Over Thirty Years
Authors: Heiferman Daniel M. , Riedy Loren N. , Rezaii Elhaum G. , Nuru Mohammed , Sloane Dayna , Joyce Cara , Moore Mary E. , Shanker Rachyl M. , Grahnke Kurt A. , Malina Giselle E. K. , Szujewski Caroline C. , Leonetti John P. , Anderson Douglas E. 
Published: December 2022

Abstract
Objective The evolution of acoustic neuroma (AN) care continues to shift focus on balancing optimized tumor resection and control with preservation of neurological function. Prior learning curve analyses of AN resection have demonstrated a plateau between 20 and 100 surgeries. In this study of 860 consecutive AN surgeries, we investigate the presence of an extended learning curve tail for AN resection.
Methods A retrospective cohort study of AN resections by a single interdisciplinary team between 1988 and 2018 was performed. Proportional odds models and restricted cubic splines were used to determine the association between the timing of surgery and odds of improved postoperative outcomes.
Results The likelihood of improved postoperative House-Brackmann (HB) scores increased in the first 400 procedures, with HB 1 at 36% in 1988 compared with 79% in 2004. While the probability of a better HB score increased over time, there was a temporary decrease in slope of the cubic spline between 2005 and 2009. The last 400 cases continued to see improvement in optimal HB outcomes: adjusted odds of HB 1 score were twofold higher in both 2005 to 2009 (adjusted odds ratio [aOR]: 2.11, 95% confidence interval [CI]: 1.38–3.22, p < 0.001) and 2010 to 2018 (aOR: 2.18, 95% CI: 1.49–3.19, p < 0.001).
Conclusion In contrast to prior studies, our study demonstrates the steepest growth for learning, as measured by rates of preservation of facial function outcomes (HB 1), occurs in the first 400 AN resections. Additionally, improvements in patient outcomes continued even 30 years into practice, underlining the importance of lifelong learning.
Comparative Analysis of Enzyme-Linked Immunosorbent Assay and Immunochromatography for Rotavirus and Adenovirus Detection in Children below Five Years with Acute Gastroenteritis
Authors: Bagali Smitha , Kakhandaki Laxmi , Karigoudar Rashmi , Wavare Sanjay , Shahapur Praveen R. , Patil Mallanagouda M. 
Published: December 2022

Abstract
Introduction The most frequent etiologies of viral gastroenteritis among young children are rotavirus and enteric adenovirus. The clinical signs and symptoms of viral gastroenteritis are not distinct enough to allow for diagnosis. For the diagnosis and treatment of acute gastroenteritis, it is preferable to use quick, simple, and low-cost procedures. This study was undertaken to determine efficacy of immune-chromatography test (ICT) in comparison with enzyme-linked immunosorbent assay (ELISA) to detect rotavirus and adenovirus antigen in fecal specimen among children less than 5 years of age with acute gastroenteritis.
Materials and Methods In a cross-sectional observational study, 314 fecal samples were collected from children aged less than 5 years with acute gastroenteritis attending or admitted to a tertiary care hospital during the 1 year study period. Samples were tested for rotavirus and adenovirus antigen using ICT and ELISA.
Results Among the 314 children evaluated, 112 (35.66%) had rotavirus infection, nine (2.86%) had adenovirus infection, and three (0.95%) had both rotavirus and adenovirus infection. This study found that ICT is 98.20% sensitive and 100% specific for the diagnosis of rotaviral diarrhea and 100% sensitive and 99.7% specific for adenovirus diarrhea, compared to ELISA.
Conclusion Immunochromatography tests used for the detection of rotavirus and adenovirus in the fecal sample showed a high degree of sensitivity and specificity. The ICT is easy to perform and rapid, and it does not require any special equipment. Hence, the ICT could be used as an alternative method for detecting viral pathogens in clinical practice.
Protein Malnutrition in BALB/c Mice: An Experimental Model Resembling Clinical Scenario
Authors: D'Souza Vinitha , RJ Madhura , Shetty Meghashree , A. Varsha , Chakraborthy Anirban , B. Mohana Kumar , A. Veena Shetty , Badanthadka Murali 
Published: December 2022

Abstract
Objectives The study aims to develop a stable malnourished experimental mice model resembling the human population for future experimental studies.
Materials and Methodology At weaning, female BALB/c mice are separated into two groups: one receiving a low protein diet (LPD, 10% protein) and the other receiving a commercially available normal pellet diet (ND, 18% protein). Model development and stability were assessed using body mass index (BMI), biochemical parameters such as glucose, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, total protein, albumin, total cholesterol, calcium, and phosphorus using serum samples at the 12th and 15th weeks of the study, antioxidant assay, and liver histopathology observation. Antioxidant assay and histopathology observation using liver tissue sample excised after euthanasia.
Results LPD mice are categorized under grade I malnutrition based on the body weight change with respect to ND as per the principles of Gomez's classification of malnutrition. A significant long-term decrease in BMI of the malnourished group indicates the development of the stable malnourished model. Elevated serum enzyme levels in the 15th week and decreased antioxidant activity suggest liver injury and oxidative stress at the cellular level in the malnourished group. Histopathology alterations in the liver tissue further strengthen these observations reported in the human population of malnutrition.
Conclusion This study confirms the development of a stable malnourished experimental model using a LPD (10% protein). This model may be used to study the role of malnutrition in the pathophysiology of any disease, drug action, and its kinetics in the future.
Outcomes and Management of Head and Neck Cancer at a South Indian Cancer Centre: A Retrospective Study
Authors: Nagarajan Murugaiyan , Banu Ramesh , Shrividhya Ananthakrishnan , Chellapandian Thirumalai Palanichamy , Rajkumar Arumugham , Mohanraj Ramaswamy 
Published: December 2022

Abstract
Introduction Head and neck cancers are one of the most common cancers in the Indian subcontinent. The trends of these cancers worldwide have drastically changed over the past 15 years. In spite of all the new technology and timely diagnosis, the treatment of these cancers is still a challenge. These cancers still continue to be a significant cause of morbidity and mortality worldwide.
Objectives To identify different patterns of care received by patients with primary head and neck cancer in a single center and analyze the outcomes of the different patterns of care received by these patients in terms of overall survival and disease-free survival.
Materials and Methods We included 707 patients with primary head and neck cancer registered and treated in our institution from January 2015 to December 2017. The demographic details of the patient, treatment received, and outcomes of treatment were collected retrospectively from our hospital's medical registry. Descriptive analysis was performed by calculating mean and standard deviation for quantitative variables, whereas frequency and proportion were calculated for categorical variables. The mean/median overall survival and recurrence-free survival were compared across various explanatory parameters using log rank–test. A p-value < 0.05 was considered statistically significant.
Results A total of 707 patients were included in the final analysis. The median age of presentation was 60 years. In total, 50% of patients presented with stage IV disease at diagnosis and 78% had a history of smoking or other tobacco use. Oral cavity was the most common primary site. Concurrent chemotherapy with radiation therapy was the most common modality of treatment used in 49% of patients: RT was the common modality of treatment in 21% patients. Fourteen percent patients were treated by only surgery. All patients who underwent treatment were included for survival analysis, which showed that the median overall survival time was 42 months (34–49 months). The median duration of disease free-survival time was 37 months (30–43 months).
Conclusion In our study, most patients presented with locally advanced disease. Multimodality treatment yielded better results. Based on our study, in early-stage cancer, where single modality treatment was used, adjuvant therapy should be tailored based on nomogram.
Anti-F-Actin Antibody Positivity on Indirect Immunofluorescence Assay Following Chinese and Alternative Medicine Therapy: A Case Report
Authors: Mahto Mala , Rai Neha , Dey Soma , Kumar Ramesh 
Published: December 2022

AbstractImmunofluorescence on human epithelial type 2 cells is the standard screening assay for the detection of antinuclear antibodies (ANA). Cytoplasmic speckled patterns are a common finding. However, the less commonly reported ones include the cytoplasmic fibrillar patterns on indirect immunofluorescence technique (IIFT). The cytoplasmic fibrillar patterns include the cytoplasmic linear (AC-15), cytoplasmic filamentous (AC-16), and cytoplasmic segmental (AC-17). We report a case of cytoplasmic linear (F-actin) detected through IIFT during ANA screening in a 77-year-old man and later reconfirmed on liver mosaic biochip through IIFT on vascular smooth muscle substrate (VSM-47) without features suggestive of anti-smooth muscle antibody involvement post-complementary and alternative medicine therapy initiation.
Evaluating Interference of Lipemia on Routine Clinical Biochemical Tests
Authors: ArulVijayaVani Subramaniam , Mohanraj Palani Selvam , Reeta Rajagambeeram 
Published: December 2022

Abstract
Objective Lipemia is an important cause of preanalytical errors in laboratory results. They affect the specimen integrity and trustworthiness of laboratory results. The present study was to assess the impact of lipemia on routine clinical chemistry analytes.
Methods Anonymous leftover serum samples with normal levels of routine biochemical parameters were pooled. Twenty such pooled serum samples were used for the study. The samples were spiked with commercially available intralipid solution (20%) to produce lipemic concentrations of 0, 400 (mild, 20 μL), 1,000 (moderate, 50 μL), and 2,000 mg/dL (severe, 100 μL). Glucose, renal function test, electrolytes, and liver function test were estimated in all the samples. Baseline data without the effect of interference was considered as true value and percentage bias for the spiked samples was calculated. Interference was considered significant if the interference bias percentage exceeded 10%.
Result Parameters like glucose, urea, creatinine, direct bilirubin, sodium, potassium, and chloride showed negative interference at mild and moderate lipemic concentration and positive interference at severe lipemic concentration. Parameters like aspartate transaminase (AST) and alanine transaminase (ALT) showed negative interference at mild and positive interference at moderate and severe lipemic concentration. Whereas uric acid, total protein, albumin, total bilirubin, alkaline phosphatase, gamma-glutamyl transferase, calcium, magnesium, and phosphorous showed positive interference at all concentrations. Significant interference (> 10%) was shown for magnesium (mild lipemia), albumin, direct bilirubin, ALT, and AST at moderate lipemic concentration. All parameters showed significant interference at severe lipemic concentration.
Conclusion All the study parameters are affected by lipemic interference at varying levels. Laboratory-specific data regarding lipemic interference at various concentrations on the clinical biochemistry parameters is needed.
Study of Hemato-morphological Features in Neuroblastoma Infiltrating Marrow
Authors: Singh Anurag , Rawat Shalini , Yadav Geeta , Kushwaha Rashmi , Verma Shailendra Prasad , Singh Uma S. 
Published: December 2022

Abstract
Objective Neuroblastoma typically affects children within the first 5 years of life and accounts for 10% of all pediatric malignancies. Neuroblastoma at onset may manifest as a localized or metastatic illness. The aim of this study was to identify hematomorphological features in neuroblastoma infiltrating marrow as well as to ascertain the prevalence of bone marrow infiltration in neuroblastoma.
Materials and Methods This retrospective study included newly diagnosed 79 cases of neuroblastoma, which were referred for bone marrow examination for the staging of the disease. Medical records were retrieved to acquire hematomorphological findings of peripheral blood and bone marrow smears. Statistical Package for Social Sciences, IBM Inc., USA, version 21.0 was used to analyze the data.
Results The interquartile age range of neuroblastoma cases was 24.0 to 72.0 months (median = 48 months) with a male to female ratio of 2.7:1. Also, 55.6% (44/79) of cases in the study population showed evidence of marrow infiltration. The bone marrow infiltration was significantly linked to thrombocytopenia (p = 0.043) and nucleated red blood cells (p = 0.003) in peripheral blood. The bone marrow smears of cases with infiltration showed a significant shift to the left in the myeloid series (p = 0.001) and an increased number of erythroid cells (p = 0.001).
Conclusion For neuroblastoma patients, a diligent, exhaustive search for infiltrating cells in bone marrow is advised if thrombocytopenia or nucleated red blood cells are identified on a peripheral blood smear and bone marrow smears showed myeloid left shift with an increased number of erythroid cells.
Comparison of Clinical Outcome between Immunocompetent and Immunocompromised Children Aged 1 to 12 Years Admitted with Acute COVID-19 Infection – A Retrospective Review
Authors: Goel Neha , Chowdhury Ritabrata Roy , Dabas Aditya , Mehndiratta Sumit , Singh Amitabh , Gera Rani 
Published: December 2022

AbstractThe pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created havoc in adults and children. Immunocompromised children are considered a high-risk group for the extreme manifestation of coronavirus disease 2019 (COVID-19) infection. There are conflicting reports on the outcome of SARS-CoV-2 disease in immunocompromised children. We aimed to find the difference in clinical outcomes of COVID-19 infection between immunocompetent and immunocompromised children. This includes a retrospective chart review of children admitted with COVID-19 infection in a tertiary care pediatric hospital in Northern India from March 1, 2021, to May 31, 2021. There were 35 COVID-19-positive children aged 1 to 12 years admitted during the study period. The study participants were divided into two groups: immunocompetent and immunocompromised patients. The clinical features, laboratory parameters, treatment needs, and outcomes in both groups were compared. Among 35 patients enrolled, 17 were immunocompromised and 18 were immunocompetent. The median duration of hospital stay, clinical features, laboratory parameters, severity of illness, treatment needs, and outcomes were comparable between the two groups. Immunocompromised children are not at a higher risk of severe COVID-19 manifestation compared to immunocompetent children.