bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health Disparities of Sexual Minority Patients Following Prostate Cancer Treatment: Results From the Restore-2 Study
Authors: Rosser B. R. Simon , Polter Elizabeth J. , Talley Kristine M. C. , Wheldon Christopher W. , Haggart Ryan , Wright Morgan , West William , Mitteldorf Darryl , Ross Michael W. , Konety Badrinath R. , Kohli Nidhi 
Published: February 2022

PurposeThe NIH has identified sexual and gender minority persons as a health disparity population but little is known about cancer outcomes in these populations. The purpose of this study was to identify disparities in sexual minority prostate cancer patient-reported outcomes, to examine within group differences, and to test for alternative explanations for identified differences.Materials and MethodsIn 2019, we recruited 401 gay and bisexual prostate cancer patients into the Restore-2 study, a randomized controlled trial of rehabilitation program tailored for sexual minority men.ResultsCompared to the normative (heterosexual) EPIC sample, participants had significantly worse urinary, bowel and hormonal function, better sexual function, and no difference on bother scores. They also had worse depression and overall mental health, and worse physical, social/family, functional, prostate specific and overall well-being quality of life outcomes. Across measures, no differences by age, gay versus bisexual orientation, race/ethnicity, and relationship status were observed. Those who had hormonal treatment had worse sexual and hormonal function than those who had radiation or surgery only. Those with a longer time since treatment had better urinary function. Differences remained when participants were matched to normative samples on cancer stage and time since treatment.ConclusionsThis, the largest study of sexual minority prostate cancer patients to date, confirms health disparities in prostate cancer quality of life outcomes. Findings appear reliable and robust. To improve the clinical care of prostate cancer, it will be important to address the health disparities experienced by sexual minority prostate cancer patients.
The Relationship Between Children's Birth Time and Short Stature
Authors: Wang Shuo , Shao Na , Ding Yiyi , Cai Hong , Zou Runmei , Wang Cheng 
Published: February 2022

BackgroundThere are few current reports on the relationship between time of birth and short stature in children. Therefore, we aimed to investigate whether there is an association between time of birth and short stature in children.Materials and MethodsIn this study, basic information was collected from 462 children aged 2–14 years old. We collected data on gender, height, height standard deviation score (SDS), weight, body mass index (BMI), serum 25(OH)D levels, date of birth, and whether the above children were short stature. Demographic description, univariate analysis, multivariate logistic regression analysis, smooth curve fitting, and threshold effects were used to explore possible linear or non-linear relationships between children's birth time and short stature.ResultsThe mean age of the 462 children was 9.76 ± 3.10 years old, and 52.16% were male. A total of 129 (27.92%) children were defined as 25(OH)D insufficiency, including 107 (38.91%) in the short stature group and 22 (11.76%) in the normal stature group. Fully adjusted logistic regression showed that the risk of short stature was reduced by 56.5% in children born in summer compared with spring (P &lt; 0.05) [odds ratio (OR): 0.435, 95% confidence interval (CI): 0.197–0.959]. A non-linear relationship was found between “sequential day of the year” and short stature from the 1st to the 250th day of the year, the risk of short stature in children is reduced by 0.6% for each day that passes (P = 0.002) (OR: 0.994, 95% CI: 0.990–0.998), and from the 250th to the 365th day of the year, the risk of short stature in children was increased by 0.8% for each day that passed (P = 0.008) (OR: 1.008, 95% CI: 1.001–1.025).ConclusionsChildren born in summer have a lower risk of short stature than spring. For children born before the 250th day of the year, “sequential day of the year” was negatively associated with short stature, and for children born after the 250th day, “sequential day of the year” was positively associated with short stature.
The Association Between Patient-Centered Communication and Primary Care Quality in Urban China: Evidence From a Standardized Patient Study
Authors: Su Min , Zhou Zhongliang , Si Yafei , Fan Xiaojing 
Published: February 2022

BackgroundEffective patient-physician communication has been considered a central clinical function and core value of health system. Currently, there are no studies directly evaluating the association between patient-centered communication (PCC) and primary care quality in urban China. This study aims to investigate the association between PCC and primary care quality.MethodsThe standardized patients were used to measure PCC and the quality of health care. We recruited 12 standardized patients from local communities presenting fixed cases (unstable angina and asthma), including 492 interactions between physicians and standardized patients across 63 CHCs in Xi'an, China. PCC was scored on three dismissions: (1) exploring disease and illness experience, (2) understanding the whole person, and (3) finding common ground. We measured the quality of the primary care by (1) accuracy of diagnosis, (2) consultation time, (3) appropriateness of treatment, (4) unnecessary exams; (5) unnecessary drugs, and (6) medical expenditure. Ordinary least-squares regression models with fixed effects were used for the continuous variables and logistic regression models with fixed effects were used for the categorical variables.ResultsThe average score of PCC1, PCC2, and PCC3 was 12.24 ± 4.04 (out of 64), 0.79 ± 0.64 (out of 3), and 10.19 ± 3.60 (out of 17), respectively. The total score of PCC was 23.22 ± 6.24 (out of 84). We found 44.11% of the visits having a correct diagnosis, and 24.19% of the visits having correct treatment. The average number of unnecessary exams and drugs was 0.91 ± 1.05, and 0.45 ± 0.82, respectively. The average total cost was 35.00 ± 41.26 CNY. After controlling for the potential confounding factors and fixed effects, the PCC increased the correct diagnosis by 10 percentage points (P &lt; 0.01), the correct treatment by 7 percentage points (P &lt; 0.01), the consultation time by 0.17 min (P &lt; 0.01), the number of unnecessary drugs by 0.03 items (P &lt; 0.01), and the medical expenditure by 1.46 CNY (P &lt; 0.01).ConclusionsThis study revealed pretty poor communication between primary care providers and patients. The PCC model has not been achieved, which could be one source of the intensified physician-patient relationship. Our findings showed the PCC model in the primary care settings has positive associations with the quality of the primary care. Interactions with a higher score of PCC were more likely to have a correct diagnosis and correct treatment, more consultation time, more unnecessary drugs, and higher medical expenditure. To improve PCC, the clinical capacity and communication skills of primary care providers need to be strengthened. Also, strategies on reforming the pay structure to better reflect the value of physicians and providing a stronger motivation for performance improvement are urgently needed.
Social Isolation and the Use of Technology in Caregiving Dyads Living With Dementia During COVID-19 Restrictions
Authors: Hoel Viktoria , Wolf-Ostermann Karin , Ambugo Eliva Atieno 
Published: February 2022

BackgroundPeople with dementia (PwD) and their informal caregivers (caregiving dyads) face multiple impacts of the COVID-19 pandemic, including restricted social support services and social isolation. With limited opportunities for caregiving dyads to participate in social activities during the pandemic, the potential of social technology to support social participation and dyadic relationships should be explored. As a part of an ongoing feasibility trial, this study assesses how COVID-19 has impacted community-dwelling dyads in a dementia caregiving context. The dyads' use of social technology and their motivations to invite technology into social interactions are explored.MethodsA pilot case study employing baseline interview data from three community-dwelling caregiving dyads. Each dyad consisted of a husband with a dementia diagnosis and his wife, who performed most caregiving tasks. Interviews were audio-recorded, transcribed verbatim, and subjected to inductive thematic analysis. Two researchers independently coded the data, and collated the codes and themes collaboratively.ResultsTwo themes and seven subthemes were identified: (i) living with dementia during COVID-19 (subthemes: social and leisure activities, dyadic interactions, adjusting as caregiver); and (ii) the role of technology in a pandemic (subthemes: facilitating social activities, facilitating dementia care-related activities, barriers and facilitators to using social technology, the underlying motivation to invite technology into interactions). Dyads who were socially active pre-COVID-19, and who managed to make good use of technology to facilitate and maintain their social engagement during COVID-19, reported to have been less negatively impacted by COVID-related social restrictions.ConclusionThe dyads differed in how COVID-19 restrictions impacted their lives and how they coped with dementia, revealing different motivations for wanting to invite technology into their social interactions. During and beyond this pandemic, social technology can be a valuable tool for promoting social participation in this population, especially when in-person social contact is restricted. Successful uptake of social technology is dependent on customizing it to the individual's needs and conditions. Therefore, efforts are needed to tackle barriers that exist for older adults in using such technology.
Symptom Clustering Patterns and Population Characteristics of COVID-19 Based on Text Clustering Method
Authors: Cheng Xiuwei , Wan Hongli , Yuan Heng , Zhou Lijun , Xiao Chongkun , Mao Suling , Li Zhirui , Hu Fengmiao , Yang Chuan , Zhu Wenhui , Zhou Jiushun , Zhang Tao 
Published: February 2022

BackgroundDescriptions of single clinical symptoms of coronavirus disease 2019 (COVID-19) have been widely reported. However, evidence of symptoms associations was still limited. We sought to explore the potential symptom clustering patterns and high-frequency symptom combinations of COVID-19 to enhance the understanding of people of this disease.MethodsIn this retrospective cohort study, a total of 1,067 COVID-19 cases were enrolled. Symptom clustering patterns were first explored by a text clustering method. Then, a multinomial logistic regression was applied to reveal the population characteristics of different symptom groups. In addition, time intervals between symptoms onset and the first visit were analyzed to consider the effect of time interval extension on the progression of symptoms.ResultsBased on text clustering, the symptoms were summarized into four groups. Group 1: no-obvious symptoms; Group 2: mainly fever and/or dry cough; Group 3: mainly upper respiratory tract infection symptoms; Group 4: mainly cardiopulmonary, systemic, and/or gastrointestinal symptoms. Apart from Group 1 with no obvious symptoms, the most frequent symptom combinations were fever only (64 cases, 47.8%), followed by dry cough only (42 cases, 31.3%) in Group 2; expectoration only (21 cases, 19.8%), followed by expectoration complicated with fever (10 cases, 9.4%) in Group 3; fatigue complicated with fever (12 cases, 4.2%), followed by headache complicated with fever was also high (11 cases, 3.8%) in Group 4. People aged 45–64 years were more likely to have symptoms of Group 4 than those aged 65 years or older (odds ratio [OR] = 2.66, 95% CI: 1.21–5.85) and at the same time had longer time intervals.ConclusionsSymptoms of COVID-19 could be divided into four clustering groups with different symptom combinations. The Group 4 symptoms (i.e., mainly cardiopulmonary, systemic, and/or gastrointestinal symptoms) happened more frequently in COVID-19 than in influenza. This distinction could help deepen the understanding of this disease. The middle-aged people have a longer time interval for medical visit and was a group that deserve more attention, from the perspective of medical delays.
Perceptions and Expectations of School-Based Professionals Surrounding School-Based Mindfulness Training in Appalachia During the COVID-19 Pandemic: A Qualitative Study
Authors: Haliwa Ilana , Layman Hannah , Coffman Jessica , Snodgrass Amy , Santer Pamela , Barlett Brittney , Long Kate , Mason Ashley , Pfost Gretchen , Harden Jenny , Dino Geri , Jarrett Traci 
Published: February 2022

BackgroundSchool-based professionals often report high burnout, particularly in geographic areas like Appalachia, where school-aged children are exposed to high levels of adverse childhood experiences, which may be exacerbated by the COVID-19 pandemic. While school-based mindfulness trainings can reduce burnout, their efficacy is influenced by the expectations of intervention personnel ahead of implementation. The present study assessed expectations and perceptions of a school-based mindfulness training among school personnel in 21 Appalachian schools during the COVID-19 pandemic.MethodsUpon enrollment in the training, staff (N= 191) responded to open ended survey questions regarding perceived impacts of COVID-19 on students, expected benefits and barriers to school-based mindfulness, and perceived community acceptance of mindfulness.ResultsSchool personnel identified social isolation and lack of structure as negative impacts of COVID-19 on students. Expected benefits of classroom mindfulness included improved coping skills, focus, and emotion regulation, whereas barriers included lack of time and student ability level (e.g., age, attention). While most respondents indicated that their community was accepting of mindfulness practices, some noted resistance to and misperceptions of mindfulness, which may illustrate the influence of local cultural norms and values on the acceptability of mental health interventions.ConclusionsOverall, these findings suggest positive expectations and relative perceived support for mindfulness practices within these Appalachian communities, including in response to negative impacts of the COVID-19 pandemic on students. Adapting practices and language to accommodate barriers such as time, student ability, and cultural misconceptions of mindfulness may increase the feasibility and efficacy of these interventions.
Validation of Sentinel-2 (MSI) and Sentinel-3 (OLCI) Water Quality Products in Turbid Estuaries Using Fixed Monitoring Stations
Authors: Salama Mhd. Suhyb , Spaias Lazaros , Poser Kathrin , Peters Steef , Laanen Marnix 
Published: February 2022

It is common in estuarine waters to place fixed monitoring stations, with the advantages of easy maintenance and continuous measurements. These two features make fixed monitoring stations indispensable for understanding the optical complexity of estuarine waters and enable an improved quantification of uncertainties in satellite-derived water quality variables. However, comparing the point-scale measurements of stationary monitoring systems to time-snapshots of satellite pixels suffers from additional uncertainties related to temporal/spatial discrepancies. This research presents a method for validating satellite-derived water quality variables with the continuous measurements of a fixed monitoring station in the Ems Dollard estuary on the Dutch-German borders. The method has two steps; first, similar in-situ measurements are grouped. Second, satellite observations are upscaled to match these point measurements in time and spatial scales. The upscaling approach was based on harmonizing the probability distribution functions of satellite observations and in-situ measurements using the first and second moments. The fixed station provided a continuous record of data on suspended particulate matter (SPM) and chlorophyll-a (Chl-a) concentrations at 1 min intervals for 1 year (2016–2017). Satellite observations were provided by Sentinel-2 (MultiSpectral Instrument, S2-MSI) and Sentinel-3 (Ocean and Land Color Instrument, S3-OLCI) sensors for the same location and time of in-situ measurements. Compared to traditional validation procedures, the proposed method has improved the overall fit and produced valuable information on the ranges of goodness-of-fit measures (slope, intercept, correlation coefficient, and normalized root-mean-square deviation). The correlation coefficient between measured and derived SPM concentrations has improved from 0.16 to 0.52 for S2-MSI and 0.14 to 0.84 for S3-OLCI. For the Chl-a matchup, the improvement was from 0.26 to 0.82 and from 0.14 to 0.63 for S2-MSI and S3-OLCI, respectively. The uncertainty in the derived SPM and Chl-a concentrations was reduced by 30 and 23% for S2-SMI and by 28 and 16% for S3-OLCI. The high correlation and reduced uncertainty signify that the matchup pairs are observing the same fluctuations in the measured variable. These new goodness-of-fit measures correspond to the results of the performed sensitivity analysis, previous literature, and reflect the inherent accuracy of the applied derivation model.
Outcomes of Salvage Lymph Node Dissection in Oligorecurrent Prostate Cancer Post Radical Prostatectomy: Experience of an Oncologic Center in Spain
Authors: Valiquette Anne S. , Vidal Crespo Natalia , Wong Augusto , Mascarós Juan M. , Gómez-Ferrer Álvaro , Collado-Serra Argimiro , Marenco Jose L. , Casanova Ramón-Borja Juan , Rubio-Briones José , Ramirez-Backhaus Miguel 
Published: February 2022

Introduction and ObjectivesWe report our experience with salvage lymph node dissection (sLND) in oligorecurrent prostate cancer (PCa) post radical prostatectomy (RP).Material and MethodsWe retrospectively analyzed data of 24 patients who underwent sLND for biochemical recurrence (BCR) post RP, from July 2012 to February 2018. sLND was performed following an extended bilateral template. Clinical and pathological characteristics of primary RP and sLND were reported. Biochemical response and initiation of additional therapy post sLND were analyzed. Survival analysis was performed using KaplanMeier curves.Results24 sLND were performed. RP specimens showed 58.3% of Gleason score 7 and 50% of locally advanced disease. Median time to BCR post RP was 24 months with a median PSA value of 1.4 ng/ml pre sLND. 75% of patients underwent imaging prior to sLND. sLND showed oligometastasis on the final pathology report in 54.2% of patients. Metastatic lymph nodes were mainly identified in the iliac artery territory (61.5%). Complete biochemical response (PSA &lt; 0.2 ng/ml) was maintained throughout the first 12 months of follow-up in 20.83% of patients and 8.33% of patients at the end of the study (median follow-up 70 months). Survival rates free of additional therapy (ADT/RT) were 45.83% at one year and 25% at 5 years.ConclusionsWe observed a biochemical response post sLND in 20.83% of our patients, lasting throughout the first year of follow up, with survival rates free of ADT and/or RT of 45.83% at one year and 25% at 5 years.
Assessment of oral health knowledge and motivation level in dental disease prevention among the population with limited mobility and specialists
Authors: Luneva Yu. A. , Soldatova L. N. , Jordanishvili A. K. 
Published: February 2022

Relevance. The level of oral health knowledge directly affects the level of oral health. The study aims to study the level of oral health and oral disease knowledge and motivation among the population with limited mobility and specialists.Materials and methods. The study analyzed the results of the target audience survey. We developed questionnaires for children and specialists on the level of knowledge of dental disease prevention, motivation for oral care education, the quality and structure of classes with children, and specialist needs to use various related materials for conducting such educational lessons. The survey involved 178 children, of which 112 had eye disorders, and 66 children composed the control group. We also interviewed 53 specialists (dentists). The children oral responses were recorded, and specialists answered the multiple-choice survey questions in writing.Results. The study results showed a low level of oral health knowledge in schoolchildren with eye disorders, despite their high motivation to study compared to the control group (systemically healthy children). The survey revealed an acute shortage of special teaching aids for visually impaired children among specialists despite the ongoing oral health education programs.Conclusions. The study concluded that it is necessary to develop and standardize specific education methods on the dental disease prevention for blind and visually impaired children.
Gambaran Upaya Keselamatan Dan Kesehatan Kerja Dalam Penggunaan Pestisida
Authors: Canita R. Made , Sudiadnyana I Wayan 
Published: February 2022

Potencial hazards that the threaten safety and health agricultural sector one of them is the use of pesticides. The pesticides are not controlled can make some trobles of health and environment pollution. The purpose of this study is to know description of occupational safety and health efforts in the use of pesticides of farmer group “Kube Amerta Abadi” In Candikuning Baturiti, Tabanan regency. This study is descriptive study. The sampling using a saturated sampling technique, in wich all members of the population are sampled. The data obtained through by interview and check up the cholinesterase of 15 members of farmer groups. The result of study are indicated that from 15 farmers, 14 farmers have a good effort of OHS planning phase. The effort of OHS implementation phase of 15 farmers all have a good effort of OHS. From 15 farmers, 9 of the farmers have the effort of OHS the bad post implementation phase, and 6 farmers have the effort of OHS the good post implementation phase. The effort of OHS in the use of pesticides 15 farmers, 8 farmers have the effort of OHS is good and 7 farmers have the effort of OHS moderate ability. From the check of cholinesterase, 4 farmers have a mild toxic and 11 farmers have suffered moderate toxic.
Hubungan Fasilitas Sanitasi Dan Kualitas Jasa Dengan Tingkat Kepuasan Pengunjung Tahura Ngurah Rai Provinsi Bali
Authors: Phartin Purwaningrum Ni Made Puti , Asmara I Wayan Suarta 
Published: February 2022

Abstract : Ngurah Rai Forest Park is one of the public recreation places with ecotourism objects that can attract visitors. The purpose of this study was to determine the correlation of sanitation facilities and service quality with level of visitor satisfaction of Ngurah Rai Forest Park At Bali Province. Research used is quantitative with a crossectional approach survey method. The sample used was 100 out of 1,323 populations using quota sampling. Based on the chi-square test results, it is obtained that sanitation facilities with sig = 0.045 (0.05), means there is a significant correlation sanitation facilities with the visitore satisfaction level with CC = 0.237, which means that the level of correlation is low, while service quality with visitor satisfaction level is obtained sig = 0,000 0.05 means that there is a significant correlation of service quality and level of visitor satisfaction with CC = 0.543 means the level of correlation is medium. The conclusion of this research is that there is a correlation between sanitation facilities and service quality with the level of satisfaction of visitors of Ngurah Rai Forest Park at Bali Province. The advice is to improve the quality of services and sanitation facilities to increase visitor satisfaction.