bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness and Cost-Effectiveness of Inactivated Vaccine to Address COVID-19 Pandemic in China: Evidence From Randomized Control Trials and Real-World Studies
Authors: Fu Yaqun , Zhao Jingyu , Wei Xia , Han Peien , Yang Li , Ren Tao , Zhan Siyan , Li Liming 
Published: July 2022

ObjectiveThis study aimed to determine the efficacy, effectiveness, and cost-effectiveness of inactivated COVID-19 vaccines (CoronaVac and BBIBP-CorV) in China using existing international clinical trials and real-world evidence.MethodsThrough a search of PubMed, Embase, Web of Science, and CNKI, studies investigating the effectiveness of inactivated COVID-19 vaccines were identified, and a meta-analysis was undertaken to synthesize the vaccine efficacy and effectiveness data. Moreover, a decision-analytic model was developed to estimate the cost-effectiveness of inactivated vaccines for combating the COVID-19 pandemic in the Chinese context from a societal perspective. Results of the meta-analysis, along with cost data from official websites and works of literature were used to populate the model. Sensitivity analysis was performed to test the robustness of the model results.ResultsA total of 24 studies were included in the meta-analysis. In comparison to no immunization, the effectiveness of inactivated vaccine against COVID-19 infection, hospitalization, ICU admission and death were 65.18% (95% CI 62.62, 67.75), 79.10% (95% CI 71.69, 86.51), 90.46% (95% CI 89.42, 91.50), and 86.69% (95% CI 85.68, 87.70); and the efficacy against COVID-19 infection and hospitalization were 70.56% (95% CI 57.87, 83.24) and 100% (95% CI 61.72, 100). Inactivated vaccine vaccination prevented more infections, hospitalizations, ICU admissions, and deaths with lower total costs, thus was cost-saving from a societal perspective in China. Base-case analysis results were robust in the one-way sensitivity analysis, and the percentage of ICU admission or death and direct medical cost ranked the top influential factors in our models. In the probabilistic sensitivity analysis, vaccination had a 100% probability of being cost-effective.ConclusionInactivated vaccine is effective in preventing COVID-19 infection, hospitalization, ICU admission and avoiding COVID-19 related death, and COVID-19 vaccination program is cost-saving from societal perspective in China.
Willingness to pay for social health insurance among public civil servants: A cross-sectional study in Dessie City Administration, North-East Ethiopia
Authors: Amilaku Eshetie Meseret , Fentaye Fasil Walelign , Mekonen Asnakew Molla , Bayked Ewunetie Mekashaw 
Published: July 2022

BackgroundThe readiness to pay for health insurance has an impact on universal health care. This study investigated the willingness of public civil servants in Dessie City Administration, North-East Ethiopia, to pay for social health insurance and associated factors.MethodsFrom April to May 2021, a cross-sectional study was undertaken. The sectors from which the samples were proportionately allocated were chosen using a multistage sampling procedure. Using their payroll list as a sampling frame, simple random sampling was done to recruit them. A semi-structured self-administered questionnaire was used to collect data. Epi Data version 3.1 was used to enter, code, and clean the data, which was then exported to SPSS version 23 for analysis. To determine relationships, bi-variable and multivariable analyses were utilized. Candidates for multivariable analysis were variables with a p-value ≤ 0.3 in bi-variable analysis. AOR with a 95% CI was used to determine the strength and direction of association. Statistical significance was defined at p-value &lt; 0.05.ResultsA total of 796 employees took part in the study, with a 94.42% response rate. Overall, 29.60% of them were willing to pay for the scheme (95% CI: 26.4, 33%). The decision to pay was influenced by favorable perception (AOR = 2.43, 95% CI: 1.72, 3.44), household income &lt; Birr 5,000 (AOR = 0.26, 95% CI: 0.14, 0.48), acute illness (AOR = 0.48, 95% CI: 0.32, 0.72), bachelor level education (AOR = 0.44, 95% CI: 0.28, 0.70), master and above level education (AOR = 0.26, 95% CI: 0.14, 0.49), and age 25–29 years (AOR = 1.97, 95 % CI: 1.08, 3.57).ConclusionThe willingness of the civil servants to pay for social health insurance was low, and it was influenced by their attitudes toward the scheme, the occurrence of severe illness, income level, educational status, and age.
Research hotspots and emerging trends of deep learning applications in orthopedics: A bibliometric and visualized study
Authors: Feng Chengyao , Zhou Xiaowen , Wang Hua , He Yu , Li Zhihong , Tu Chao 
Published: July 2022

BackgroundAs a research hotspot, deep learning has been continuously combined with various research fields in medicine. Recently, there is a growing amount of deep learning-based researches in orthopedics. This bibliometric analysis aimed to identify the hotspots of deep learning applications in orthopedics in recent years and infer future research trends.MethodsWe screened global publication on deep learning applications in orthopedics by accessing the Web of Science Core Collection. The articles and reviews were collected without language and time restrictions. Citespace was applied to conduct the bibliometric analysis of the publications.ResultsA total of 822 articles and reviews were finally retrieved. The analysis showed that the application of deep learning in orthopedics has great prospects for development based on the annual publications. The most prolific country is the USA, followed by China. University of California San Francisco, and Skeletal Radiology are the most prolific institution and journal, respectively. LeCun Y is the most frequently cited author, and Nature has the highest impact factor in the cited journals. The current hot keywords are convolutional neural network, classification, segmentation, diagnosis, image, fracture, and osteoarthritis. The burst keywords are risk factor, identification, localization, and surgery. The timeline viewer showed two recent research directions for bone tumors and osteoporosis.ConclusionPublications on deep learning applications in orthopedics have increased in recent years, with the USA being the most prolific. The current research mainly focused on classifying, diagnosing and risk predicting in osteoarthritis and fractures from medical images. Future research directions may put emphasis on reducing intraoperative risk, predicting the occurrence of postoperative complications, screening for osteoporosis, and identification and classification of bone tumors from conventional imaging.
Respiratory response to finger clamping in dogs under general anesthesia: A descriptive pilot study
Authors: Sylvain Lepape , Jerneja Sredensek , Karine Portier 
Published: July 2022

Aim of the studyThe aim of this study was to assess the effects of a nociceptive stimulus on respiratory variables in anesthetized dogs.Material and methodEleven dogs received acepromazine administered intramuscularly (IM) at a dose of 0.04 mg kg−1 45 mins before induction of anesthesia. Loss of consciousness was obtained with midazolam at 0.2 mg kg−1 and propofol administered at a dose of 2 mg kg−1 intravenously (IV). Orotracheal intubation was performed and anesthesia was maintained with isoflurane in 100% oxygen. Inspired (VTi) and expired (VTe) tidal volume (VT), minute volume (VM), inspiratory and expiratory time (Ti; Te) were measured and recorded twice a second by a spirometer. The Drive (VT/Ti) and Timing [Ti/(Ti+ Te)] were calculated.After stabilizing the depth of anesthesia the variables measured by the spirometer were recorded for 5 mins [T0−5-T0]. Then (T0) interdigital clamping of the hind leg was performed until a withdrawal movement was observed. If no reaction occurred, the clamp was left in place for 60s. After removal of the clamp, respiratory variables were measured continuously for another 5 mins [T0-T0+5]. At T0+5 morphine (0.2 mg kg−1 IV) was administered. Five minutes later (T0+10), a second clamp test was performed, using the same procedure. At T0+15 the data recording was stopped.ResultThe results showed a large variation in the individual values of Drive and Timing and are presented in a descriptive manner. The observation of Drive values over time showed variations following nociceptive stimuli. Drive appears to have increased only for those dogs that did not move during the stimulus, and were therefore pinched for a full 60 s. In contrast, the study of the Timing values revealed no difference between the data before and after nociceptive stimulation. However Timing seems to increase after morphine administration.ConclusionDrive remains a parameter that needs to be studied in depth to determine its sensitivity and precocity to monitor acute nociception.
Pain Interference, Resilience, and Perceived Well-Being During COVID-19: Differences Between Women With and Without Trauma Exposure Prior to the Pandemic
Authors: Serrano-Ibáñez Elena R. , Ramírez-Maestre Carmen , Ruiz-Párraga Gema T. , Esteve Rosa , López-Martínez Alicia E. 
Published: July 2022

Objectives: The aim of this study was to investigate the consequences of the COVID-19 pandemic in women with non-malignant chronic pain, and to determine whether women exposed to traumatic situations prior to the outbreak would be at a higher risk of negative health impacts.Methods: A total of 365 women were divided into three subgroups according to whether or not they had experienced a traumatic event prior to COVID-19. They completed an online survey.Results: Significant differences were found between groups during lockdown: 1) more psychological abuse was experienced by the group of women who had experienced an interpersonal traumatic event prior to the pandemic than in the other subgroups; 2) physical activity levels were higher and scores on pain interference were lower in women in the non-traumatized subgroup than in the other subgroups; 3) pain interference was predicted by pain intensity, decreased social support, and resilience, whereas perceived well-being was predicted by pain interference.Conclusion: Women who had experienced a traumatic event prior to the pandemic suffered worse consequences of the COVID-19 lockdown, particularly greater pain interference, although resilience was shown to both mitigate pain interference and enhance perceived well-being.
On Baskakov operators preserving the exponential function
Authors: Yilmaz Ovgu Gurel , Gupta Vijay , Aral Ali 
Published: July 2022

In this paper, we are concerned about the King-type Baskakov operators defined by means of the preserving functions \(e_{0}\) and \(e^{2ax},\ a>0\) fixed.
Using the modulus of continuity, we show the uniform convergence of new operators to \(f\). Also, by analyzing the asymptotic behavior of King-type operators with a Voronovskaya-type theorem, we establish shape preserving properties using the generalized convexity.
High order approximation theory for Banach space valued functions
Authors: Anastassiou George A. 
Published: July 2022

Here we study quantitatively the high degree of approximation of sequences of linear operators acting on Banach space valued di§erentiable functions to the unit operator. These operators are bounded by real positive linear companion operators. The Banach spaces considered here are general and no positivity assumption is made on the initial linear operators whose we study their approximation properties. We derive pointwise and uniform estimates which imply the approximation of these operators to the unit assuming di§erentiability of functions. At the end we study the special case where the high order derivative of the on hand function fulÖlls a convexity condition resulting into sharper estimates.
MR3724631
A numerical comparison between two exact simplicial methods for solving a capacitated 4-index transportation problem
Authors: Zitouni Rachid , Achache Mohamed 
Published: July 2022

In this paper, we deal with a numerical comparison between two exact simplicial methods for solving a capacitated four-index transportation problem. The first method was developed by R. Zitouni and A. Keraghel for solving this problem [Resolution of a capacitated transportation problem with four subscripts, Kybernetes, Emerald journals, 32, 9/10: 1450-1463 (2003)]. The second approach is the well-known simplex method.
We show across some obtained numerical results that the first algorithm competes well with the simplex method.
Caputo fractional approximation by sublinear operators
Authors: Anastassiou George A. 
Published: July 2022

Here we consider the approximation of functions by sublinear positive operators with applications to a big variety of Max-Product operators under Caputo fractional differentiability.
Our study is based on our general fractional results about positive sublinear operators. We produce Jackson type inequalities under simple initial conditions. So our approach is quantitative by producing inequalities with their right hand sides involving the modulus of continuity of fractional derivative of the function underapproximation.
The Scientific Society and the Spiritual Society in the Novel ‘Iraiyuthir Kaadu’
Authors: S Kiruthiga , S Gandhidurai 
Published: July 2022

People's lives are intended to various changes in today's society. Novel literature is required in particular to record those changes because novel and society are intertwined. Indira Soundarrajan's ‘Irayuthir Kaadu’ is a testament to the social history novel which is a mix of historical and contemporary events. The research area of this article is the scientific society and the spiritual society of the above-mentioned novel. The Sociological Approach has been adopted for this research to analyze the dependency of people on technological gadgets and the state of spirituality in today’s society.
ORIENTASI PASAR DAN ORIENTASI KEWIRAUSAHAAN DALAM MEMPENGARUHI KINERJA PEMASARAN DI MASA RECOVERY PANDEMI COVID-19
Authors: Astuti Indah Yuni , Munir Miftahul 
Published: July 2022

The COVID-19 pandemic has become a separate obstacle for society in general, ranging from social constraints to improving the economy of a society in particular. This situation must be taken into consideration by the household craft industry players to be able to survive and develop their business activities in generating productivity and profits through market orientation and entrepreneurship strategies. The purpose of this study was to determine the effect of market orientation and entrepreneurship on the marketing performance of the wood craft industry business actors in the village area of ​​Boro Kedungwaru, Tulungagung. The population and samples that became the object of this study were all wood craft business actor as many as 45 respondents. Sampling using saturated sampling technique, and data collection using a questionnaire with a Likert scale as the instrument. Data analysis used validity and reliability test, multiple linear regression test, determinant coefficient test and hypothesis testing (t test & F test). The results of the research conducted showed that 1) It was a significant and partial influence between market orientation and entrepreneurial orientation on the marketing performance of household handicraft business actors during the recovery period of the COVID-19 pandemic. 2). Market orientation and entrepreneurial orientation have a positive and significant impact simultaneously on the marketing performance of household handicraft business actors during the recovery period of the COVID-19 pandemic. The results of this study indicate that market orientation and entrepreneurial orientation have urgency and contribution in supporting the marketing performance of wood handicraft business actors especially during the COVID-19 pandemic.
Keywords: Market Orientation, Entrepreneurship Orientation, Marketing Performance
ANALISA PERENCANAAN STRATEGI BISNIS SI/TI MENGGUNAKAN METODE WARD & PEPPARD PADA PT. XYZ
Authors: Setiawan Wawan , Fajriyah Nurul 
Published: July 2022

Planning a good system strategy and information technology is expected to help companies achieve business goals. The achievement of these business objectives must be supported by all parts of the company, so as to create a value chain that will provide margins for the company. PT. XYZ is a company engaged in the baking chocolate processing industry located in Tangerang Regency. Data collection methods used by researchers are observation, interview and literature study. Based on the interview results, there are still problems regarding the absence of a system of long-term mutually beneficial relations with customers. Lack of adequate human resources, as well as not maximizing the management of research data for chocolate product stability analysis. The method used in the research of strategic planning for Information Systems and Information Technology is Ward and Peppard. In this method several stages are carried out, including: Analysis of the business external environment using the PEST method and analysis of five Porter competition models, while analyzing the business's internal environment using a SWOT, Value Chain and CSF analysis. Then mapping the application portfolio using the Mcfarland Strategic Grid method. Based on an analysis of the external and internal environment of the business IS / IT, it is necessary to create an E-CRM system, a product information research and quality system and an employee evaluation system
Keywords: Business, Planning, Strategy, Ward and Peppard
PENGARUH EVALUASI KREDIT DAN PENGAWASAN KREDIT TERHADAP RISIKO KREDIT MACET
Authors: Timuneno Antonius Yohanes William 
Published: July 2022

The research background is risk of the loan credit which is the one problem which inseperable from the operations system in credit service unions in district Oebobo of Kupang City. In observation the loan default, the efforts of tackling was involved two important factors were credit evaluation and control credit. This research was conducted in 15 units of credit unions that were selected based on the criteria previously and the sample were 30 persons from credit management and supervisory elements. Technique in collecting data is observation interview, questionnnary, and documentation. The result proved that the Credit Evaluation and Credit Control had the significant partially influence to minimizing the Risk of Loan default on the credit union in district Oebobo of Kupang City through simple Linear Regression Analysis results in agreement line standard. This research also proved that the managements in credit union have to maintain and applying the evaluation and control credit system that usefull to minimize the level of loan default risk. Although it can be minimized with applying the balance credit.
Keywords: Credit Control, Credit Evaluation, Risk of Loan
Pengembangan LKS Pada Materi Limit Menggunakan Model Pembelajaran Group Investigation Berbasis Komunikasi Matematis
Authors: Mayasari Dian , Meirista Etriana , Jayanti Dwi Putri 
Published: July 2022

Abstrak: Penelitian ini mengembangkan suatu bahan ajar berupa lembar kegiatan siswa yang berbasis komunikasi matematis dengan model pembelajaran group investigation. Pengembangan LKS menggunakan model pembelajaran group investigation ini bertujuan untuk melatih kemampuan komunikasi matematis siswa pada materi limit. Model pengembangan yang digunakan adalah 4-D terdiri atas empat tahapan yaitu define, design, develop dan disseminate. Penelitian hanya dilakukan sampai uji coba terbatas pada tahap develop karena waktu yang terbatas. Penelitian ini dilaksanakan di MA Al-Hikmah Merauke pada kelas XII IPA sebagai sampel uji coba terbatas yang berjumlah 12 siswa. Teknik pengumpulan data dengan memberikan angket kevalidan kepada validator untuk mengukur kevalidan produk serta angket kepraktisan kepada guru dan siswa untuk mengukur kepraktisan produk. Analisis data dilakukan dengan menghitung persentase nilai dari angket yang diberikan kepada validator dan responden. Hasil penelitian menunju kan bahwa LKS dengan model pembelajaran group investigation berbasis komunikasi matematis berada pada kriteria valid dan praktis. Produk yang dikembangkan sudah layak digunakan untuk uji coba lapangan dan pembelajaran di sekolah.
Abstract: This study developed a teaching material in the form of student’s worksheet based on mathematical communication with the group investigation learning model. The development of student’s worksheet using the group investigation learning model was aimed at training student mathematical communication skills on the limit material. The research model used is 4-D consisting of four stages, namely define, design, develop and disseminate. The research was only conducted until the trial at the develop stage due to limited time. This research was conducted at MA Al-Hikmah Merauke in class XII IPA as a limited trial sample, amounting to 12 students. Data collection techniques was by providing validity questionnaires to validators to measure product validity and practicality questionnaires to teachers and students to measure the practicality of the product. Data analysis was performed by calculating the percentage value of the questionnaire given to the validators and respondents. The results showed that student worksheets with the group investigation learning model based on mathematical communication were in valid and practical criteria. The product developed is suitable for use for field trials and learning in schools.
Lesson Study dalam Meningkatkan Aktivitas dan Hasil Belajar Siswa SMP pada Pokok Bahasan Prisma dan Limas Tegak
Authors: Indraswari Nur Fitriyah , Fitriyah Lilis Mariyatul 
Published: July 2022

Abstrak: Dalam proses pembelajaran, masalah yang sering dijumpai diantaranya guru kurang mampu memberi stimulus kepada siswa dalam belajar sehingga hal ini mengakibatkan rendahnya hasil belajar siswa. Dalam hal ini, peneliti memilih lesson study dengan metode discovery learning untuk meningkatkan hasil belajar siswa. Tujuan penelitian ini adalah untuk mendeskripsikan penggunaan lesson study terhadap peningkatan aktivitas dan hasil belajar siswa pada pokok bahasan prisma dan limas tegak di kelas VIII SMP Negeri 3 Pamekasan. PTK dalam penelitian ini dilaksanakan secara kolaboratif antara guru mata pelajaran matematika kelas VIII dan peneliti. Untuk memperoleh data peneliti menggunakan observasi dan tes untuk mengetahui peningkatan aktivitas dan hasil belajar siswa. Setelah diadakan penelitian tentang kegiatan lesson study di kelas VIII mengalami peningkatan yang cukup signifikan. Berdasarkan hasil penelitian, penulis mengambil kesimpulan bahwa lesson study dengan menggunakan metode discovery learning dapat meningkatkan hasil belajar siswa.
Abstract: In the learning process, problems that are often encountered include teachers being unable to provide stimulus to students in learning so that this results in low student achievement. In this case, the authors chose lesson study with discovery learning methods to improve student achievement. The purpose of this study was to describe the use of lesson study to increase student activity and achievement on the subject of prisms and upright pyramids in class VIII junior high school 3 pamekasan. PTK in this study was carried out collaboratively between the VIII grade mathematics teacher and the researcher. To obtain data, researchers used observation and tests to determine the increase in student activity and achievement. After conducting research on lesson study activities in class VIII experienced a significant increase. Based on the research results, the authors conclude that lesson study using discovery learning method can improve student achievement.