bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is hyperlipazemia a poor prognostic factor in patients with COVID-19 ?
Authors: COŞKUN Orhan , ÇAPRAZ Mustafa , CİHANGİROĞLU Mustafa , KAYA Ahmet Turan 
Published: May 2022

Introduction: COVID-19 disease may pose a considerable health threat to healthy individuals and individuals with comorbidity. The SARS-CoV-2 virus affects the respiratory tract and may cause damage to the pancreas by binding to the ACE-2 receptor in the pancreas. In our study, we investigated the effects of hyperlipasemia on morbidity and mortality in patients diagnosed with COVID-19.
Material and Method: In this study, 2350 patients diagnosed with COVID-19 between November 2020 and December 2020 were retrospectively reviewed. Other possible causes of hyperlipasemia were excluded. Hyperlipasemia secondary to COVID-19 was detected in 338 patients. These patients were divided into two groups based on their lipase elevation rates.
Results: Hyperlipasemia was detected in 14.4% of the patients diagnosed with COVID-19, and severe hyperlipasemia (>3x) was detected in 2.3%. The mean age of the patients was 64±13.8 (18-92), of which 59.5% (201) were male. In our study, 24 patients (1%) were diagnosed with acute pancreatitis. When compared according to lipase level, a significant difference was found between the groups regarding the history of HT, CCI score, development of ARF at follow-up, development of ARDS, need for ICU hospitalization, need for intubation, length of stay in ICU, and death rates. A weak correlation was found in the correlation analysis between hyperlipasemia and ARDS development and mortality.
Conclusion: Elevated lipase levels were associated with poor prognosis and mortality in patients with COVID-19 infection.
MR imaging characteristics of Morel-Lavallee lesions in pediatric patients
Authors: KAZCI Ömer , ŞENBİL Düzgün Can , KAYNAK ŞAHAP Seda , UCAN Berna , AYDIN Sonay 
Published: May 2022

Aim: Morel-Lavallée syndrome (MLS) is a serious posttraumatic soft tissue injury in which the subcutaneous tissues are separated from the underlying fascia by glove-finger (closed type) peeling and replaced by a cavity filled with hematoma and fat. It is most commonly seen in the trochanter major, but it can also be found in the flank, hip, and lumbodorsal regions. The goal of this study is to define the typical findings of MLS in order to avoid misdiagnosis and delay in patient treatment.
Material and Method: This retrospective study was approved by the Institutional Review Board. Informed consent was waived due to the retrospective nature of the study. Between 2015 and 2021, MR images and clinical follow-ups of 22 pediatric patients with clinical and radiological Morel-Lavallée lesions (MLL) were reviewed retrospectively. All patients were evaluated using 1.5T or 3T power MR devices (Siemens Healthineers, Erlangen, Germany).
Results: Of 22 patients diagnosed with MLS, 77% (n=17) were male and 23% (n=5) were female. Patients ranged in age from 7 to 18 years, with a mean of 13.2 years (+/-2,3). The locations of MLL were knee (77%, n=17, 15 patients had anterior knee and 2 patients had posterior knee involvement), hip (14%, n=3) and thigh (9%, n=2) in order of frequency. These lesions all had a similar ovoid shape. The majority of patients (18/22) received solely conservative management but three patients underwent percutaneous drainage.
Conclusion: In our study, the importance of differential diagnosis of MLL from traumatic collections and the importance of MRI findings in diagnosis and treatment were discussed. Accurate diagnosis and treatment of MLL are critical, as the lesion's size may increase as a result of delayed treatment, causing skin necrosis and denervation due to the mass effect.
Evaluation of the alteration in retinal features following bariatric surgery in patients with morbid obesity
Authors: ÇAY Ferhat , SAHIN VURAL Gozde 
Published: May 2022

Aim: The aim of the study is to evaluate the effect of bariatric surgery on the retina and choroid in non-diabetic and non-hypertensive patients with morbid obesity using optic coherence tomography (OCT) retrospectively.
Material and Method: Seventy-four eyes of seventy-four patients who have been underwent sleeve gasterectomy for morbid obesity in Balıkesir University Medicine Faculty & February 2019 and November 2020 were evaluated. All participants has a detailed ophthalmologic examination including best-corrected visual acuity (BCVA), intraocular pressure (IOP), slit-lamp biomicroscopy, retinal examination through non-dilated pupil via 90 D fundus lens, the retinal thickness (central, perifoveal, and parafoveal superior/nasal/inferior/temporal quadrants), and choroidal thickness through optic coherence tomography (RTVue XR Avanti, Optovue) in immediate preoperative and postoperative sixth-month. All values were compared.
Results: The macular thickness was increased significantly in all quadrants in postoperative visits (p0.05). The correlation between preoperative BMI and preoperative choroidal thickness was significant (R: 0.416, p
Does your sleeping position affect your shoulder pain?
Authors: AYGÜN BİLECİK Nilüfer , BÜYÜKVURAL ŞEN Sıdıka , YAŞA ÖZTÜRK Gülşah 
Published: May 2022

Aim: This study aimed to evaluate patients with shoulder pain according to their sleeping positions based on their clinical and magnetic resonance imaging (MRI) findings and to determine possible factors affecting shoulder pain.
Material and Method: A total of 115 patients were included in the study. The severity of shoulder pain was evaluated with the visual analog scale (VAS), shoulder function was evaluated with the simple shoulder test, and the ability to perform physical activities was evaluated with the QuickDASH questionnaire. The biceps tendon, rotator cuff (RC), subacromial-subdeltoid bursa, glenohumeral joint (GHJ), and acromioclavicular joint (ACJ) were evaluated using MRI.
Results: Of the patients with shoulder pain, 66.1% were female, 50.4% were primary school graduates, 53.9% were housewives, and 41.7% had a systemic disease. The mean age of the patients was 50.48±13.61 years while the median BMI and VAS values were 26.1 (18.2-41.4) and 8 (2-10), respectively. Considering the sleeping positions, it was found that 39.1% (most common) of the patients were sleeping in the fetus position, and considering the results of patients’ MRI examinations, the most common problem was related to the pathologies of the supraspinatus tendon (42.6%). It was found that sleep quality, which was poor in all patients, was worse in females (p=0.311), in those over 50 years of age (p=0.007), and those with a systemic disease (0.325). It was discovered that Pittsburgh's sleep quality index score was generally worse in those who slept in the soldier position and in the log position (p>0.05). The rates of pathologies of the supraspinatus tendon were found to be the highest in those that slept in the fetus position (p=0.931). It was also found that the rates of impingement, bicipital tendinitis, combined problems, and adhesive capsulitis did not differ significantly according to sleeping positions. Although occupational variables for supraspinatus degeneration remained significant in the model, having a desk job statistically significantly increased the probability of supraspinatus degeneration by 3.38 times when compared to being a housewife (95% CI=1.143-9.996; p=0.028) and it was identified that the probability of acromioclavicular degeneration increased by 1.16 times for every 1-unit increase in BMI.
Conclusion: Different sleeping positions may predispose to different shoulder pathologies and shoulder pain, and shoulder pathologies may lead to deterioration of sleep quality, especially in older patients. For this reason, suggesting correct and appropriate sleeping positions may be a useful treatment method in reducing pain and disability and increasing sleep quality.
Can Saccharomyces boulardii treat and eradicate Helicobacter pylori among children instead of bismuth?
Authors: KEÇELİ BAŞARAN Meryem , ZENGİN Nur Şeyma 
Published: May 2022

Aim: The objective of this study is to compare the use of Saccharomyces boulardii (S. boulardii) in eradicating Helicobacter pylori (H. pylori) in children as an alternative to bismuth, which has a limited scope of application due to its side effects.
Material and Method: Included in the study were 220 pediatric patients with symptomatic H. pylori gastritis. The patients were randomized into three treatment groups. Patients who received bismuth or S. boulardii in addition to the standard triple therapy for 14 days were compared with the control group who received only triple therapy.
Results: Analysis of the bismuth, S. boulardii, and control groups’ treatment success showed that the H. pylori eradication rate was highest among study participants who received bismuth (95.2%), followed by patients who received S. boulardii (92.4%). The most frequent side effects were observed in the patient group that received bismuth (17.5%).
Conclusion: Although bismuth continues to be successful in eradicating H. pylori, alternative treatment protocols are necessary because of its side effects and limited use in pediatric patients. S. boulardii can be administered instead when bismuth can not serve as alternative due to its side effects.
Measurement of 0 to 2 age normal eyeball volume by the use of multidetector computed tomography
Authors: KAYA Mustafa , GÜRÜN Enes , AKDULUM İsmail 
Published: May 2022

Aim: To diagnose microphthalmia or macrophthalmia, it is necessary to know the normal reference values of the eyeball volumes. However, we do not have a table of normal reference values to evaluate normal eyeball volume at 0-2 years of age. To compensate for this deficiency, we aimed to detect normal eyeball volumes in the age group of 0-2 years with multidetector computed tomography (MDCT).
Material and Method: A total of 90 patients who underwent MDCT with a prior diagnosis of head trauma but without traumatic pathology were included in the study. Patients were divided into age groups of 0-1 months, 2-6 months, 7-12 months, 13-24 months. The mean values of patients in each age group were examined with a 95% confidence interval. The correlation between bilateral eyeball volumes and age was calculated using the Pearson correlation test. The relationship between the age groups and the volume of the eyeball was studied using one-way ANOVA test. The relationship between eyeball volumes and sex was evaluated using the Mann Whitney U test.
Results: Mean eyeball volume was measured as 3.91±0.54 cm3 for 0-1 months, 4.44 ±0.66 cm3 for 2-6 months, 5.81 ±0.68 cm3 for 7-12 months, and 5.83±1.09 cm3 for 13-24 months. A strong positive correlation was observed between eyeball volume and age (p < 0.001). There was no statistically significant relationship between eyeball volume and sex (p > 0.05). No statistically significant difference was observed between right eyeball volume and left eyeball volume ( p> 0.05).
Conclusions: The increase in eyeball volume is most rapid in the first year of life. In this study, the reference eyeball volumes were determined in order to properly assess this rapid increase.
Integrity loss of glycosylated hemoglobin with deepening anemia
Authors: AYDIN Bünyamin , GÖNDEREN Aysun 
Published: May 2022

Introduction: Iron deficiency anemia (IDA) has been shown to cause a false increase in glycosylated hemoglobin (HBA1c), but how much increase in hemoglobin (Hgb) causes a certain decrease in HBA1c remains unknown. Knowledge of this ratio will enable more accurate clinical diagnosis and follow-up of diabetes. This study aimed to investigate whether IDA causes a decrease in HBA1c and if it does, how much of a decrease it causes.
Material and Method: One hundred and twenty-two patients with IDA made up the study group and sixty-two health volunteers formed the control group. 270 mg ferrous sulphate (=80 mg elemental iron) were administered to the study group each day, orally for 3 months, and a control of age/sex matched healthy participants were monitored. Hgb, serum iron, serum iron binding capacity (SIBC), ferritin and HbA1c levels of all participants were measured and compared at baseline and at the third month of the study.
Results: There was a significant decrease in HbA1c and SIBC levels at baseline and 3 months in the study group (p
Influence of different ligation methods on force and moment generation in a simulated condition of the maxillary crowded anterior dentition with linguo-version and rotation
Authors: Kim Sunmin , Yonemitsu Ikuo , Takemura Hiroshi , Shimoda Kunio , Suga Kazuhiro , Soga Kohei , Ono Takashi , Uo Motohiro 
Published: May 2022

BACKGROUND: Most orthodontic cases consist of varying degrees of crowding. To manage crowded dentitions, nickel-titanium archwires with various ligation methods are often used. OBJECTIVE: We aimed to investigate the effect of different ligation methods with respect to force and moment and suggest the efficient ligation method for treating rotation and displacement simultaneously. METHODS: We built a model that simulated the three anterior teeth of the maxilla. The teeth on the two ends were fixed, and the middle tooth was set in several different positions by manipulating the amount of displacement in bucco-lingual direction and rotation angle. The measurements were taken with three different ligation methods of self-ligation (SL), elastomeric o-ring ligation on both side wings (EB), and on one side wings (EO). RESULTS: The magnitude of linguo-buccal force exceeded the standard optimal force in each condition examined and was significantly larger in EB than in other ligation methods. Moreover, the magnitude of moment generation with SL was suitable in the 0.0 mm linguo-version, whereas it was suitable with EO in the linguo-version ranging 1.0–3.0 mm. CONCLUSIONS: The ligation method significantly affected the force and moment. SL and EO are recommended in dentitions with light and deep lingual displacements, respectively.
Preparation and mechanical properties analysis of porous structure for bone tissue engineering
Authors: Cui Jingbin , Yi Yali , Zhang Jinming , Chai Liping , Jin Herong 
Published: May 2022

BACKGROUND: With the increasing aging of population, the incidence rate of diseases such as fracture and osteoporosis has been increasing. The demand for implant in Department of orthopedics has increased. The elastic modulus of the existing solid metal implant is much higher than that of human bone tissue, and it is easy to produce stress shielding effect after operation, which causes complications such as loosening of prosthesis and low fusion efficiency. OBJECTIVE: In order to solve the mismatch of elastic modulus between solid metal orthopedic implants and human bone tissue, metal structures with excellent mechanical properties were prepared. METHODS: The porous structure was designed by spatial dot matrix method, and the metal porous structure was prepared based on selective laser melting 3D printing technology. The residual stress in the preparation process was eliminated by vacuum annealing heat treatment, and the static compression experiment was carried out to study the effects of different pore shape and porosity parameters on the compressive yield strength and elastic modulus of porous structure. The performance changes of porous structure before and after heat treatment were compared, and the porous structure meeting the performance requirements of human bone tissue was selected. RESULTS: The porous structure prepared by selective laser melting technology met the requirements of human bone tissue. The elastic modulus was as low as 0.74 GPa and the compressive yield strength is 201.91 MPa; After annealing heat treatment, the compressive yield strength of porous structure decreased, the maximum change was 3.69%, the elastic modulus increased, and the maximum change was 8.69%. CONCLUSIONS: For the porous structure with the same pore shape, the lower the porosity, the better the mechanical properties of the porous structure. For the same porosity, the comprehensive mechanical properties of dodecahedral porous structure were the best and octahedral porous structure was the worst; the porous structure after annealing heat treatment was more conducive to meet the performance requirements of human bone tissue.
Effects of drought-tolerant grapevine rootstocks on the mineral contents and fatty acid compositions of grape seeds
Authors: Odabaşioğlu Mehmet İlhan , Gürsöz Sadettin 
Published: May 2022

BACKGROUND: As the interest in foods with positive effects on human health has increased in recent decades, the importance of the mineral contents and oil compositions of grape seeds has been better understood. However, research on grape seeds to date has largely focused on effects on health and the usability of grape seeds in the food industry and animal feeds. In agricultural research, grape seeds have generally been evaluated as a source of genes in breeding new varieties and as propagation material. OBJECTIVE: Unlike previous studies, this study not only investigates the effect of variety on the changes of pomological properties, fatty acid compositions, and oil, protein, and mineral contents of grape seeds; it also aims to determine the effects of grape rootstocks and growing seasons on those changes. METHODS: The seeds of five grape varieties (Red Globe, Trakya Ilkeren, Ata Sarisi, Hatun Parmagi, and Horoz Karasi) grafted onto drought-tolerant grape rootstocks (1103P and 110R) were analyzed during the growing seasons of 2017 and 2018. RESULTS: Seed size, moisture and oil contents, major fatty acids (palmitic, oleic, and linoleic), and levels of saturated fatty acids, monounsaturated fatty acids, unsaturated fatty acids, and boron varied by variety, rootstock, and season. However, the effects of growing seasons and varieties on the seeds were not limited to these findings; effects were also seen for seed vitality, protein content, and N, K, Ca, and Fe levels of the seeds, among others. CONCLUSIONS: Genotype was found to be the main factor causing changes in the fatty acid compositions and mineral contents of grape seeds. When the factors that we investigated were ordered based on the changes they caused for seeds in general, the sequence that appeared was genotype > growing season > grape rootstock.
User experience of assistive apps among people with visual impairment
Authors: Kim Hyung Nam 
Published: May 2022

BACKGROUND: Today, various emerging assistive applications (apps) running on smartphones have been introduced such as Seeing AI, TapTapSee, and BeMyEyes apps. The assistive apps are designed to assist people with visual impairment in navigating unfamiliar environments, reading text, identifying objects and persons. Yet, little is known about how those with visual impairment perceive the assistive apps. OBJECTIVE: This study aims to advance knowledge of user experience with those assistive apps. METHODS: To address the knowledge gap, this study conducted phone interviews with a convenience sample of 30 individuals with visual impairment. RESULTS: The results indicated that those with visual impairment showed a range of preferences, needs, and concerns about user interfaces and interactions with the assistive apps. DISCUSSIONS: Given their needs and concerns, this study offered a set of facilitators to promote user adoption of the assistive apps, which should be valuable guidance to user interface/interaction designers in the field.
The median effective volume of ultrasound-guided thoracic paravertebral nerve block with 0.3% ropivacaine in radical thoracoscopic surgery for lung cancer
Authors: Zhang Wen-Qing , Li Jia-Bin , Huang Ye , Huang Na-Qing , Huang Fei-Bin , Huang Qiao-Wen , Jiang Li-Wei , Lu Zhi-Wei 
Published: May 2022

BACKGROUND: Ultrasound-guided needle placement has revolutionized the thoracic paravertebral block technique and can be applied in thoracoscopic surgery. OBJECTIVE: This study investigated the median effective volume (EV50) of an ultrasound-guided single shot of 0.3% ropivacaine used as a thoracic paravertebral nerve block for the radical thoracoscopic resection of lung cancer. METHODS: A total of 27 patients who received a single shot of ultrasound-guided thoracic paravertebral nerve block and underwent radical thoracoscopic resection of lung cancer were enrolled in this study between February 10 and August 13, 2018. All patients were rated as ASA grades I or II. Using ultrasound as a guide, the block needle was gradually pushed through the lateral costotransverse ligaments to the thoracic paravertebral space by the in-plane technique. After confirming the absence of blood or cerebrospinal fluid, 1–2 ml of 0.3% ropivacaine hydrochloride was injected to confirm that the position of the needle was appropriate, and a pre-determined volume of 0.3% ropivacaine hydrochloride was then administered to the patients. Sensory testing by pinprick was performed every 5 minutes for 30 minutes following the thoracic paravertebral block injection to identify the time segments during which the loss of sensation to the pinprick and its blocking effect occurred. RESULTS: All patients completed the study and 14 (51.8%) had a successful block. CONCLUSION: The EV50 of 0.3% ropivacaine was 18.46 ml (95% CI 17.09–19.95 ml) and the EV95 was 20.89 ml.
Clinical Study of Pain in Right Iliac Fossa
Authors: Kumar Pramod 
Published: May 2022

Background: To study the clinical profile of pain in right iliac fossa.
Methods: 100 patients with signs and symptoms of right iliac fossa mass admitted in Hospital were identified and were studied by taking detailed clinical history, physical examination and were subjected to various investigations like x ray erect abdomen, chest x-ray, contrast x-ray .
Result: In this study of out of 100 cases, 71.00% of cases were related to appendicular pathology either in the form of appendicular mass or appendicular abscess. There were 9.00% cases of Ileocaecal tuberculosis.
Conclusion: Appendicular lump remains the most common cause for right iliac fossa pain. Ileocaecal tuberculosis is one of the most important differential diagnoses for pain abdomen.
Keywords: Appendicitis, , Right Iliac Fossa Mass, Pain
Authors: Ramayanti Eva Dwi , Yunalia Endang Mei , Samudra Wahyu Sukma 
Published: May 2022

Introduction: An elderly person is someone who is in the age range of 45-60 years and above. At this age, the elderly are susceptible to hypertension or increased blood pressure due to degenerative processes. Slow Deep Breathing is one of the complementary therapies by adjusting the breath to provide relaxation to the body so that it can lower blood pressure. The purpose of this study is to prove whether there is an effect of Slow Deep Breathing therapy on the level of hypertension at the elderly. Methods: This research is a Pre Experiment with one group pra-post test design. The population of this study was 17 people and the number of samples was 15 people using Simple Random Sampling. Results: From the results of the statistical test with the Wilcoxon test, it was found that there was an effect of slow deep breathing therapy on the level of hypertension in. Discussion: This therapy is able to help the release of endorphins in the body so that blood pressure is vasodilated so that blood pressure can decrease. Increased oxygenation and smooth perfusion in the body makes blood pressure decrease.

Kata Kunci : Hipertension, Eldely, Slow deep breathing exercise