bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosoziale Notfallversorgung von Kindern nach hoch belastenden Lebenserfahrungen
Authors: Finkeldei Simon , Kern Tita , Rinne-Wolf Susanna 
Published: September 2022

ZusammenfassungHoch belastende Lebensereignisse wie die Erfahrung einer lebensbedrohlichen Situation oder das Bezeugen von plötzlichem Tod, schwerer Verletzung oder Suizid stellen für die psychische Verarbeitung eine außergewöhnliche Herausforderung dar. Sie stehen in kausalem Zusammenhang mit dem Risiko, an verschiedenen psychischen und psychosomatischen Traumafolgestörungen zu erkranken. Diesem Wissen folgend, sind die Aufgaben der Psychosozialen Notfallversorgung (PSNV): die Prävention psychosozialer Belastungsfolgen, die Früherkennung weiteren Hilfs- oder Versorgungsbedarfs und die Bereitstellung adäquater Hilfe zur Belastungsverarbeitung. Sind Kinder von einem Notfallereignis betroffen, befinden sich diese aufgrund entwicklungspsychologischer Aspekte in einer anderen Position als erwachsene Betroffene.Der vorliegende Beitrag beschreibt praxisnah die Besonderheiten in der Notfallversorgung der Zielgruppe Kinder. Dabei geht er anhand ausgewählter Forschungsbefunde aus den Feldern Psychotraumatologie und Psychosoziale Notfallversorgung insbesondere der Frage nach, welche Auswirkungen das Bezugspersonenverhalten auf die kindliche Verarbeitung von Notfallereignissen hat. Entsprechende Folgerungen für die Praxis der PSNV werden gezogen. Darüber hinaus werden allgemeine Empfehlungen zur Akutbetreuung von Kindern vorgestellt und Herausforderungen in der Praxis diskutiert.Die Psychosoziale Notfallversorgung von Kindern erfordert ein im Vergleich zu der Begleitung von erwachsenen Betroffenen angepasstes Vorgehen. Verhaltenskompetenz und Stabilität der Bezugspersonen haben Einfluss auf die kindlichen Verarbeitungsmöglichkeiten. Abhängig vom Zeitpunkt der Intervention bedarf die PSNV unterschiedlicher Kompetenzen. Der niederschwellige Zugang zu Hilfsangeboten stellt in der Versorgungspraxis eine Herausforderung dar.
Synthesis and characterization of non-stoichiometric Li1.1Co0.3Fe2.1O4 ferrite nanoparticles for humidity sensors
Authors: Ateia Mahmoud A. , Ateia Ebtesam E. , Mosry Mohamed , Arman M. M. 
Published: September 2022

AbstractA humidity sensor plays a crucial role in determining the efficiency of materials and the precision of apparatuses. To measure and control humidity, a non-stoichiometric Li1.1Co0.3Fe2.1O4 mesopore sensor is synthesized by a modified citrate auto combustion technique. The XRD study confirms that prepared nanoparticles are cubic spinel structures having an Fd3m space group. The crystallite size is approximately 36 nm. Thermal analysis measurements show that samples become thermally stable at a temperature of 600 °C. Additionally, the kinetic studies of the prepared samples are calculated via a pseudo-first-order kinetic model. The temperature dependence of AC conductivity is found to increase with increasing temperature. These observations are explained in various models. The resistivity mechanism of humidity sensors is studied via complex impedance spectroscopy (CIS). Its impedance data are fitted to a corresponding circuit, to achieve a simulation of the sample under study. This fitting is detected by the Nyquist plot (Cole–Cole). The obtained data confirm that the studied samples are very sensitive to humidity and can be commercially used as a humidity sensing element.
Graphical abstract
Testicular germ cell tumours’ clinical stage I: comparison of surveillance with adjuvant treatment strategies regarding recurrence rates and overall survival—a systematic review
Authors: Ruf Christian G. , Schmidt Stefanie , Kliesch Sabine , Oing Christoph , Pfister David , Busch Jonas , Heinzelbecker Julia , Winter Christian , Zengerling Friedemann , Albers Peter , Oechsle Karin , Krege Susanne , Lackner Julia , Dieckmann Klaus-Peter 
Published: September 2022

Abstract
Purpose
Testicular germ cell tumours (GCTs) represent the most common malignancy in young adult males with two thirds of all cases presenting with clinical stage I (CSI). Active surveillance is the management modality mostly favoured by current guidelines. This systematic review assesses the treatment results in CSI patients concerning recurrence rate and overall survival in non-seminoma (NS) and pure seminoma (SE) resulting from surveillance in comparison to adjuvant strategies.

Methods/systematic review
We performed a systematic literature review confining the search to most recent studies published 2010–2021 that reported direct comparisons of surveillance to adjuvant management. We searched Medline and the Cochrane Library with additional hand-searching of reference lists to identify relevant studies. Data extraction and quality assessment of included studies were performed with stratification for histology (NS vs. SE) and treatment modalities. The results were tabulated and evaluated with descriptive statistical methods.

Results
Thirty-four studies met the inclusion criteria. In NS patients relapse rates were 12 to 37%, 0 to 10%, and 0 to 11.8% for surveillance, chemotherapy and for retroperitoneal lymph node dissection (RPLND) while overall survival rates were 90.7−100%, 91.7−100%, and 97−99.1%, respectively. In SE CSI, relapse rates were 0−22.3%, 0−5%, and 0−12.5% for surveillance, radiotherapy, chemotherapy, while overall survival rates were 84.1−98.7%, 83.5−100%, and 92.3−100%, respectively.

Conclusion
In both histologic subgroups, active surveillance offers almost identical overall survival as adjuvant management strategies, however, at the expense of higher relapse rates. Each of the management strategies in CSI GCT patients have specific merits and shared-decision-making is advised to tailor treatment.
DPOAEs and tympanal membrane vibrations reveal adaptations of the sexually dimorphic ear of the concave-eared torrent frog, Odorrana tormota
Authors: Cobo-Cuan Ariadna , Feng Albert S. , Zhang Fang , Narins Peter M. 
Published: September 2022

AbstractWhile most anuran species are highly vocal, few of them seem to be endowed with a complex call repertoire. Odorrana tormota, combines a remarkable vocalization complexity with auditory sensitivity over an extended spectral range spanning from audible to ultrasonic frequencies. This species is also exceptional for its ability to modify its middle ear tuning by closing the Eustachian tubes (ET). Using scanning laser Doppler vibrometry, the tympanal vibrations were measured to investigate if the tuning shift caused by the ET closure contributes to intraspecific acoustic communication. To gain insight into the inner ear frequency selectivity and sensitivity of this species, distortion product otoacoustic emissions were recorded at multiple frequency-level combinations. Our measurements of inner ear responses indicated that in O. tormota each sex is more sensitive to the frequencies of the other sex's vocalizations, female ears are more sensitive to 2–7 kHz, while male ears are more sensitive to 3–15 kHz. We also found that in both sexes the ET closure impacts the sensitivity of the middle and inner ear at frequencies used for communication with conspecifics. This study broadens our understanding of peripheral auditory mechanisms contributing to intraspecific acoustic communication in anurans.
Contemporary treatment of mitral valve disease with transcatheter mitral valve implantation
Authors: Wienemann Hendrik , Mauri Victor , Ochs Laurin , Körber Maria Isabel , Eghbalzadeh Kaveh , Iliadis Christos , Halbach Marcel , Wahlers Thorsten , Baldus Stephan , Adam Matti , Kuhn Elmar 
Published: September 2022

Abstract
Background
Transcatheter mitral valve implantation (TMVI) with self-expanding (SAV) or balloon-expandable (BAV) valves are rising as promising treatment options for high-risk patients with symptomatic mitral valve (MVD) disease unsuitable for alternative treatment options.

Aims
The aim of this study was to examine the clinical, procedural and outcome parameters of patients undergoing SAV or BAV for MVD.

Methods
In this observational and single-center case series, fifteen consecutive patients treated with the Tendyne Mitral Valve System (SAV) and thirty-one patients treated with SAPIEN prosthesis (BAV) were included.

Results
The patients (aged 78 years [interquartile range (IQR): 65.5 to 83.1 years], 41% women, EuroSCORE II 10.3% [IQR: 5.5 to 17.0%] were similar regarding baseline characteristics, despite a higher rate of prior heart valve surgery and prevalence of MV stenosis in the SAV-group. At discharge, the SAV-group had a mean transvalvular gradient of 4.2 mmHg, whereas the BAV-group had a mean transvalvular gradient of 6.2 mmHg. None or trace paravalvular leakage (PVL) was assessed in 85% in SAV-group and 80% in the BAV-group. 320 day all-cause and cardiac mortality rates were comparable in both groups (SAV: 26.7% vs BAV: 20%, p = 0.60). Four deaths occurred early in the SAV-group until 32 days of follow-up.

Conclusions
In high-risk patients with MVD, TMVI presents a promising treatment option with encouraging mid-term outcomes and good valve durability. TMVI either with BAV or SAV may be developed to an established treatment option.

Graphical abstract
Simulation of the drawdown and its duration in Lévy models via stick-breaking Gaussian approximation
Authors: González Cázares Jorge , Mijatović Aleksandar 
Published: September 2022

AbstractWe develop a computational method for expected functionals of the drawdown and its duration in exponential Lévy models. It is based on a novel simulation algorithm for the joint law of the state, supremum and time the supremum is attained of the Gaussian approximation for a general Lévy process. We bound the bias for various locally Lipschitz and discontinuous payoffs arising in applications and analyse the computational complexities of the corresponding Monte Carlo and multilevel Monte Carlo estimators. Monte Carlo methods for Lévy processes (using Gaussian approximation) have been analysed for Lipschitz payoffs, in which case the computational complexity of our algorithm is up to two orders of magnitude smaller when the jump activity is high. At the core of our approach are bounds on certain Wasserstein distances, obtained via the novel stick-breaking Gaussian (SBG) coupling between a Lévy process and its Gaussian approximation. Numerical performance, based on the implementation in Cázares and Mijatović (SBG approximation. GitHub repository. Available online at https://github.com/jorgeignaciogc/SBG.jl (2020)), exhibits a good agreement with our theoretical bounds. Numerical evidence suggests that our algorithm remains stable and accurate when estimating Greeks for barrier options and outperforms the “obvious” algorithm for finite-jump-activity Lévy processes.
Local Well-Posedness of a System Describing Laser-Plasma Interactions
Authors: Herr Sebastian , Kato Isao , Kinoshita Shinya , Spitz Martin 
Published: September 2022

AbstractA degenerate Zakharov system arises as a model for the description of laser-plasma interactions. It is a coupled system of a Schrödinger and a wave equation with a non-dispersive direction. In this paper, a new local well-posedness result for rough initial data is established. The proof is based on an efficient use of local smoothing and maximal function norms.
Airborne combined photogrammetry—infrared thermography applied to landslide remote monitoring
Authors: Vivaldi V. , Bordoni M. , Mineo S. , Crozi M. , Pappalardo G. , Meisina C. 
Published: September 2022

AbstractThe combination between two remote surveying methods is presented herein as a pioneering approach for landslide airborne monitoring. The survey of an active landslide by UAV-based RGB photogrammetry and infrared thermography, sided by the knowledge of the field condition, allowed increasing the scientific experience on the remote sensing of slope instability phenomena by analyzing multiple aspects related to the evolution of key slope features. In this research, the state and distribution of activity of a landslide was monitored by matching data arising from three-dimensional models of the slope, built by exploiting the aerial RGB photogrammetric technology, and thermal outcomes, resulting from the airborne application of infrared thermography principles. In this frame, thermal anomalies detected during different monitoring campaigns allowed recognizing peculiar features along the unstable slope that could be related to specific kinematic elements involved in the landslide activity. Forming cracks, developing scarps, wet terrain portions, and loose material are some of the elements that could be located by integrating thermal outcomes with Digital Surface Models of the slope. Thanks to the different thermal behavior of such elements, strengthened herein by a novel approach of thermal data processing (i.e. the study of thermal slope profiles), the lateral and retrogressive evolution of the studied movement was first hypothesized and then verified in field. Achieved results show that the location of thermal anomalies well corresponds to field structures, which sometimes are hardly detectable by in situ or RGB surveys, thus suggesting the high potential of the methodological approach developed for this study. The scientific validity of presented data gains relevance thanks to the positive field validation. This paves the way to further studies aimed at implementing the infrared aerial survey of landslides, which surely could bring benefits to practical applications in terms of survey speed and spatial coverage, especially in areas characterized by bad field logistics.
Effect of Clinical and Genetic Factors on the Development of Postoperative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG) in Egyptian Patients Receiving Beta-Blockers
Authors: El Gindy Dina M. K. , Solayman Mohamed H. , Khorshid Ramy , Schaalan Mona F. , El Wakeel Lamia M. 
Published: September 2022

Abstract
Purpose
Prophylactic beta-blockers are recommended to prevent postoperative atrial fibrillation (POAF) after coronary artery bypass grafting (CABG). Polymorphisms in the beta-1 adrenergic receptor (ADRB1) and G protein-coupled receptor kinase 5 (GRK5) genes are associated with variable responses to beta-blockers. The aim of this study was to determine the clinical and genetic factors that influence the response to beta-blockers for POAF prophylaxis after CABG.

Methods
Patients undergoing isolated CABG and receiving prophylactic beta-blockers (n = 249) were prospectively recruited and followed up for 6 postoperative days. Genotyping of ADRB1 rs1801253, and 3 GRK5 SNPs (rs3740563, rs10787959, and rs17098707) was performed.

Results
Of the 249 patients, 52 patients (20.8%) experienced POAF. Age, hypertension, vasopressor use, calculated POAF risk score, GRK5 rs2230345 T-allele, and GRK5 rs3740563 A-allele were associated with POAF despite beta-blocker prophylaxis. The multivariate analysis revealed that age [odds ratio (OR) 1.06, 95% CI 1.02–1.11, p = 0.003] and GRK5 rs2230345 T-allele [OR 2.81, 95% CI 1.39–5.67, p = 0.004] were independent predictors of POAF after CABG despite beta-blocker prophylaxis.

Conclusion
GRK5 rs2230345 T-allele carriers were less responsive than AA genotype carriers to prophylactic beta-blockers for the prevention of POAF after CABG.
The study was registered on http://clinicaltrials.gov in March 2019, with trial registration number (TRN): NCT03871647.
Crime and crisis in China’s P2P online lending market: a comparative analysis of fraud
Authors: Huang Li , Pontell Henry N. 
Published: September 2022

AbstractWhite-collar criminality continues to be a significant issue in countries with differing levels of economic development. This paper provides a comparative analysis of white-collar crime and crises through an examination of the recent peer-to-peer (P2P) online lending crash in China. It considers criminological findings from major United States crises in light of China’s P2P online lending market failure through the lens of white-collar crime theory and research. The findings show that fraud was a main contributor to the P2P online lending crash and that various structural factors facilitated financial crimes that caused the collapse of the P2P online lending market. This study indicates that, similar to the U.S. experience, crime-facilitative environments allowed for endemic fraud in China’s online lending industry. It suggests that a primarily reactive approach to financial crime is less effective than a proactive system of compliance that includes more comprehensive and transparent financial regulation and law enforcement.
Selective alarm call mimicry in the sexual display of the male superb lyrebird (Menura novaehollandiae)
Authors: Crisologo Taylor L. , Dzielski Sarah A. , Purcell James R. , Webster Michael S. , Welbergen Justin A. , Dalziell Anastasia H. 
Published: September 2022

AbstractDespite much research on mimicry, little is known about the ecology of dynamic mimetic signals involving mimicry of multiple species. Some of the most conspicuous examples of phenotypically plastic mimicry are produced by oscine passerines, where vocal production learning enables some species to mimic multiple models and flexibly adjust what they mimic and when. While singing from a perch, male superb lyrebirds (Menura novaehollandiae) accurately imitate multiple songs and calls of over 20 species of bird. However, at key moments within their multimodal displays performed on display arenas on the forest floor, males mimic a small number of mobbing-alarm calls creating the acoustic illusion of a mixed-species mobbing flock (‘D-song’). Using observations from camera footage and a field-based playback experiment, we tested six hypotheses for alarm call model selection within D-song. Mimicked species were remarkably invariant, with 79% of D-song made up of imitations of just three different bird species. Males did not mimic the most common species in their general environment, but neither did they mimic rare species. Instead, males imitated the mobbing-alarm calls of heterospecific birds that foraged on or near the forest floor. Indeed, males primarily mimicked the alarm calls of heterospecific species that foraged alongside lyrebirds and were likely to appear together in experimentally-induced, terrestrial mobbing flocks. These findings support the hypothesis that males mimic a cue of a terrestrial predatory threat to lyrebirds, most likely to exploit the antipredator behaviour of female lyrebirds. Our study illustrates the importance of investigating the drivers of model selection in dynamic multi-model mimicry.
Antibacterial activity of silver nitrate on Pseudomonas aeruginosa bacteria using Calvet calorimetry
Authors: Aveledo Ricardo , Aveledo Alberto , Lago Natividad , Mato Marta M. , Legido José L. 
Published: September 2022

AbstractThis study aimed to use microcalorimetry to analyze the real-time effect that silver nitrate has on one of the most common bacteria involved in severe infections in current medical practice. Using a Calvet microcalorimeter, the heat output produced by Pseudomonas aeruginosa was determined when exposed to concentrations of silver nitrate from 0 to 3 mol⋅m−3, and a saturated solution. Under physiological human body temperature, for 46 h, thermographic curves were obtained. The maximum voltage peaks (Vmax) and the total amount of heat exchanged (Q) were determined. The results showed a bactericidal effect, with a minimum inhibitory concentration (MIC) of silver nitrate of 0.75 mol⋅m−3, showing a Vmax of 93 μV and Q of 193 kJ. With higher concentrations of this metallic solution, the results highlighted the proportional negative effect that silver nitrate has in Pseudomonas aeruginosa growth.
Impact of NMDA receptor activation on DNA damage in PC12 neuron-like cell cultures in the presence of β-amyloid peptides
Authors: Wiatrak Benita , Mieszała Przemysław , Gąsiorowski Kazimierz 
Published: September 2022

Abstract
Objective
This study aimed to investigate the effect of low nanomolar concentrations of Aβ1–40 and Aβ25–35 on DNA double-strand breaks following NMDA activation of cells.

Materials and methods
After incubating the differentiated PC12 cells with Aβ25−35, Aβ1−40 or Aβ1−42 for 24 h, the culture was washed and stimulated for 15 min with NMDA. Then, tests were performed at four-time intervals from stimulation to assess the viability of the culture, the level of oxygen free radicals, and the γH2AX and pATM kinase. NMDAR1 expression was also evaluated by performing immunocytochemical staining.

Results
It was found that amyloid peptides in nanomolar concentrations reduce double-stranded DNA breaks after NMDA neuron activation. A slight antioxidant effect was also demonstrated when measured 120 min after NMDA cell activation.

Conclusion
The NMDA stimulation of PC12 cells led to a rapid increase in the number of double-stranded DNA breaks in the cells and is assumed to be the initial step in IEG activation and LTP induction. The effect of Aβ on the reduction of double-strand breaks after NMDA cell stimulation indicates that at concentrations similar to physiological amyloid peptides, it may reduce the mobilization of the neuronal response to stimuli, leading to inhibition of LTP induction and decreasing synaptic plasticity in the early stages of Alzheimer’s disease.
Optical properties of iodine-based electrolyte used in bifacial dye-sensitized solar cells
Authors: Abdellatif Sameh O. 
Published: September 2022

AbstractAs third-generation solar cells, dye-sensitized solar cells (DSSCs) can show bifacial harvesting capabilities by utilizing transparent conducting oxides as a counter electrode. Herein, the electrolyte is considered a critical layer from the optical perspective. In this paper, an attempt to estimate the optical properties of Iodine-based electrolytes, typically used in dye-sensitized solar cells, is demonstrated. The refractive index for electrolyte as an effective medium is calculated to be 1.4535 ± 0.005 for an effective thin film of 33.4 ± 0.5 μm thickness, using the near-infrared Fabry–Perot resonances. The extinction (absorption and scattering) and dispersion spectra for the prepared electrolyte were fitted using Lorentz–Dude (LD) model. Finally, the utility of the extracted optical parameters was examined through a finite difference time domain solver, Massachusetts Institute for Technology Electromagnetic Equation Propagation. The simulated optical transmission spectrum perfectly agreed with the measured spectrum with less than 0.1% root–mean–square error. The demonstrated attempt to accurately estimate the refractive index of electrolyte used in DSSCs fabrication may impacted theoreticians who are interested with the optoelectronic modelling of such electrochemical cells, as well as those dealing with optoelectronic devices informatics.
Directing the Way—Receptor and Chemical Targeting Strategies for Nucleic Acid Delivery
Authors: Steffens Ricarda Carolin , Wagner Ernst 
Published: September 2022

AbstractNucleic acid therapeutics have shown great potential for the treatment of numerous diseases, such as genetic disorders, cancer and infections. Moreover, they have been successfully used as vaccines during the COVID-19 pandemic. In order to unfold full therapeutical potential, these nano agents have to overcome several barriers. Therefore, directed transport to specific tissues and cell types remains a central challenge to receive carrier systems with enhanced efficiency and desired biodistribution profiles. Active targeting strategies include receptor-targeting, mediating cellular uptake based on ligand-receptor interactions, and chemical targeting, enabling cell-specific delivery as a consequence of chemically and structurally modified carriers. With a focus on synthetic delivery systems including polyplexes, lipid-based systems such as lipoplexes and lipid nanoparticles, and direct conjugates optimized for various types of nucleic acids (DNA, mRNA, siRNA, miRNA, oligonucleotides), we highlight recent achievements, exemplified by several nucleic acid drugs on the market, and discuss challenges for targeted delivery to different organs such as brain, eye, liver, lung, spleen and musclein vivo.