bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between Decision-Making, Time Perspective and Stress
Authors: Mehrotra Sheetal , Rangaiah Babu , Kathi Srujana 
Published: November 2022

Abstract
Decision-making is a process of gathering information, organizing, and making appropriate choices. Time perspective refers to the ways one perceives the past, present, and future. Every decision-making style dwells in one of these temporal orientations. Within the process of decision-making, there is likely to be some degree of stress. The current study explores the association between Decision-Making Styles, Time Perspective, and Stress among college students (n = 120). Tools used were the General Decision-Making Style (GDMS), the short version of the Zimbardo Time Perspective Inventory (ZTPI-short), and the Perceived Stress Scale (PSS). Results showed a significant association between decision-making styles, time perspective, and stress. Further, decision-making was found to be influenced by temporal orientations and stress levels. Furthermore, this article also proposes to discuss the application value of decision-making in the process of addressing the challenges associated with career and other real-life decisions.
The Cognitive Value of Aesthetic Emotions
Authors: Consoli Gianluca 
Published: November 2022

Abstract
Over the last two decades there have been considerable advancements in conceptual understanding and empirical findings on aesthetic emotions, one of the most popular topics in neurocognitive sciences and the scientific approaches to aesthetics. The paper proposes an empirical-theoretical review suggesting that aesthetic emotions have a strong cognitive potential in so far that they can enhance emotional intelligence. In particular, the review refers to the so-called ‘ability mental model’ of emotional intelligence and stresses evidence showing that aesthetic emotions can improve all the four dimensions of this model: perceiving emotions, using emotions to facilitate thought, understanding emotions, and self-regulating emotions.
Lady Mary Wortley Montagu: the Epistolary Woman, Because Women Could Not Be Called Philosophers, Scientists, or Inventors
Authors: Mastrantonio Monica 
Published: November 2022

Abstract
In the past, Lady Mary Wortley Montagu has been associated with two roles: her experience in the Embassy of Turkey, highlighting cultural diversity, and her transnational travels. The aim of this article is to argue that she was more than a literary aristocrat who described habits and customs from abroad. Drawing on her collected letters, with special emphasis on letters that move beyond descriptions of Istanbul, this article notes that she was also a vaccine entrepreneur, and a journalist of political and urban issues, as well as philosophical issues. In the passages discussed here, she describes and comments on trade, products, pavement, fashion, and social class. It is high time for epistolary studies to shed its biases and to consider aspects that have been overlooked in the depiction of a secular woman of feelings and emotions. Many letter writers from the sixteenth and seventeenth century were already politically and artistically engaged feminists who used letters with precision and expertise. Lady Mary Wortley Montagu, as she signed her letters, was one of them. Her letters contribute significantly to building a transcultural view of the world in which diversity and knowledge contribute to a wider perspective on reality, and they provide new opportunities to learn more about what the world was like in her day.
Association of Mammary Gland Disease With Metabolic Syndrome Factors in Japanese Women—Case-Control Study Based on Health Screening Results
Authors: Sumida Sakika , Iida Tadayuki , Yoshikawa Masao , Nagaoka Kaoru 
Published: November 2022

Background: The association of obesity with breast cancer is clear. Although body mass index (BMI) is used as an indicator of obesity, its accuracy remains questionable. Although, there factors for diagnosing metabolic syndrome are caused by obesity, the association with breast cancer has not been clarified. Methods: Women who underwent breast cancer screening with mammography and measurements of metabolic syndrome factors, including waist circumference, blood glucose, triglycerides, HDL (high-density lipoprotein) cholesterol levels, and systolic and diastolic pressure, twice within a 2-year period were enrolled (n = 314), with a final sample size of 256. To determine the presence of mammary gland disease, 2 expert physicians interpreted radiogram findings, with category 3 or higher shown by mammography considered to indicate an abnormality. Results and Conclusions: Waist circumference at the initial measurement was marginally significant as a risk factor for onset of mammary gland disease (odds ratio [OR] = 1.036, P = .045) and thus was concluded to be a risk factor for disease onset. Although not significant, a 2-year increase in systolic and diastolic blood pressure has been presumed to be risk factors (systolic: OR = 1.020, P = .085, diastolic: OR = 1.040, P = .065), while high levels of HDL cholesterol have been presumed to protect against the disease (OR = 0.982, P = .064). Based on these results, waist circumference and blood pressure are speculated to be related to development of mammary gland disease.
Short-term efficacy of angiotensin receptor-neprilysin inhibitor treatment in patients with ST-segment elevation myocardial infarction with reduced ejection fraction after primary percutaneous coronary intervention: a propensity score matching study
Authors: Zhang Qun , Qiao Bao , Han Yu , Sun Shukun , Wang Bailu , Wei Shujian 
Published: November 2022

Abstract
Background
Acute myocardial infarction (AMI) causes a series of pathophysiological changes, including myocardial necrosis, myocardial edema, and microvascular damage. These changes eventually lead to severe cardiovascular events, such as ventricular remodeling, heart failure, and papillary dysfunction. Impaired cardiac function after ST-segment elevation myocardial infarction (STEMI) often manifests as a decrease in left ventricular ejection fraction (LVEF). Clinical trials have shown that angiotensin receptor-neprilysin inhibitor (ARNI) treatment has the potential to improve LVEF in patients with STEMI after primary percutaneous coronary intervention (PPCI).

Objective
The purpose of this study was to evaluate the short-term efficacy of ARNI versus angiotensin-converting enzyme inhibitor (ACEI) treatment in patients with STEMI who exhibit reduced LVEF after PPCI.

Methods
A total of 169 patients with STEMI exhibiting post-PPCI LVEF below 50% who were orally treated with ARNI between December 2017 and August 2020 were selected as the experimental group. A total of 136 patients with STEMI exhibiting post-PPCI LVEF below 50% who were orally treated with an ACEI between January 2016 and August 2020 were selected as the control group. LVEF was measured using cardiac ultrasonography during hospitalization and 3 months after discharge. Linear and logistic regression analyses were performed to compare patient demographics and hospitalization variables to evaluate the risk factors for change and rate of improvement in LVEF. Propensity score matching (PSM) was used to account for confounding factors.

Results
After PSM, the study cohort consisted of 81 patients in the ARNI group and 123 in the ACEI group. After an average follow-up period of 3 months, no significant difference was noted in the LVEF improvement rate between the experimental and control groups (P = 0.475, 95% CI: -0.062 to 0.134). Multivariate logistic regression analysis also indicated no significant correlation between the change in LVEF and oral ARNI treatment in patients with STEMI exhibiting reduced LVEF after PPCI (P > 0.05).

Conclusion
The short-term effect of ARNI treatment on the cardiac function of patients with STEMI and reduced LVEF after PPCI is not superior to that of ACEI treatment.
Circulating CD8+CD122+ T cells as a prognostic indicator of pancreatic cancer
Authors: Teramatsu Katsuhito , Oono Takamasa , Oyama Koki , Fujimori Nao , Murakami Masatoshi , Yasumori Sho , Ohno Akihisa , Matsumoto Kazuhide , Takeno Ayumu , Nakata Kohei , Nakamura Masafumi , Ogawa Yoshihiro 
Published: November 2022

Abstract
Purpose
The distribution of tissue infiltrating lymphocytes has been shown to affect the prognosis of patients with pancreatic cancer in some previous studies. However, the role of peripheral lymphocytes in pancreatic cancer remains debated. The purpose of this study was to analyze the peripheral subtypes of T lymphocytes, and establish their association with the prognosis of patients with pancreatic cancer.

Methods
Blood and tissue samples were collected from patients with metastatic pancreatic cancer (n = 54), resectable pancreatic cancer (n = 12), and benign pancreatic cysts (n = 52) between April 2019 and January 2022 and analyzed.

Results
Patients with metastatic pancreatic cancer had a larger proportion of both tumor-suppressive and tumor-promoting cells than those with benign pancreatic cysts. In addition, the proportion of peripheral CD4+ T cells positively correlated with the survival of patients with metastatic pancreatic cancer, and the proportion of peripheral CD8+CD122+ T cells was associated with early mortality (< 90 days). After chemotherapy, CD8+CD122+ T cells decreased in patients who had a partial response or stable disease. Moreover, by analyzing resected specimens, we first proved that the existence of CD8+CD122+ T cells in a tumor microenvironment (TME) depends on their proportion in peripheral blood.

Conclusion
Circulating CD8+CD122+ T cells can be a prognostic indicator in patients with pancreatic cancer.
Occupational risk variation of nasopharyngeal cancer in the Nordic countries
Authors: Carpén Timo , Gille Evelina , Hammarstedt-Nordenvall Lalle , Hansen Johnni , Heikkinen Sanna , Lynge Elsebeth , Selander Jenny , Mehlum Ingrid Sivesind , Torfadottir Jóhanna Eyrún , Mäkitie Antti , Pukkala Eero 
Published: November 2022

Abstract
Background
The aim of this study was to estimate occupational risk variation in the incidence of nasopharyngeal cancer (NPC) in a large population-based cohort of the Nordic Occupational Cancer (NOCCA) study.

Methods
This study is based on a cohort of almost 15 million persons from Denmark, Finland, Iceland, Norway and Sweden, with 2898 nasopharyngeal cancer cases diagnosed in 1961–2005. The data on occupations were gathered from population censuses and cancer data from the national cancer registries. Standardized incidence ratios (SIR) with 95% confidence intervals (CI) were estimated using the national NPC incidence rates as the reference.

Results
There were 1980 male and 918 female NPC patients. The highest SIRs of NPC were observed among male waiters (SIR 3.69, 95% CI 1.91–6.45) and cooks and stewards (SIR 2.24, 95% CI 1.16–3.91). Among women, launderers had the highest SIR of NPC (2.04, 95% CI 1.02–3.65). Significantly decreased SIRs were found among male farmers (SIR 0.79, 95% CI 0.68–0.92) and male textile workers (SIR 0.49, 95% CI 0.22–0.93).

Conclusions
This study suggests that NPC may be associated with several work-related exposure agents such as smoking, kitchen air pollution and solvents. In future, occupational exposure-risk relations should be studied to understand more about causality and to assess effective prevention strategies.
Contextual factors influencing the implementation of a new midwife education programme in India: a qualitative study
Authors: Erlandsson Kerstin , Jha Paridhi , Sharma Bharati , Bogren Malin 
Published: November 2022

AbstractThe Indian Government has committed to educate 90,000 midwives in accordance with international norms. This goal is critical as midwives provide evidence-based, high-quality midwifery care. There is a need to explore the contextual factors influencing this new midwifery education programme. Hence, the aim of this study is to explore contextual factors influencing the implementation of the national midwifery education programme for midwifery educators and the future Nurse Practitioners in Midwifery (NPMs) in India. A qualitative research design was used, with data collected through focus group discussions (n = 8) with a total of 27 participants representing seven national and international organisations supporting the Indian Government in its midwifery initiative. Transcribed interviews were analysed using content analysis. This study on contextual factors influencing the implementation of the new midwifery education programme in India showed that organisational and administrative processes are complex and the development of midwifery educators and nurse practitioners in midwifery needs to be fast tracked. The education of educators and future midwives in India, and elsewhere in similar settings, could benefit from efforts to simplify the organisational and administration processes and, in parallel, mobilize innovative teaching and learning approaches to bridge theory and practice.
Effect of up to 30-days of storage at different temperatures on detection of feline kidney injury molecule-1 in urine
Authors: Milaszewska Aleksandra , Defarges Alice , Oblak Michelle , Brisson Brigitte , Monteith Gabrielle , Bienzle Dorothee 
Published: November 2022

Abstract
Background
In humans, kidney injury molecule-1 (KIM-1) is a biomarker of acute kidney injury that can be quantified in urine. Preliminary investigation in cats with experimentally induced acute kidney injury showed that KIM-1 urine concentration correlated with kidney injury histopathology scores. A lateral flow assay (LFA) has recently become available for patient-side feline KIM-1 measurement. In vitro parameters of the assay have not yet been determined. The objectives of this study were to determine detection of KIM-1 in urine stored at different temperatures over time, to establish the linear range of the LFA, and to assess the intra-assay repeatability of measurements.

Results
Ten urine samples with a range of KIM-1 concentrations were stored at room temperature (22o C), 4o C or -20o C, and tested with the LFA on days 0, 1, 2, 3, 7, 14, and 30. The concentration of KIM-1 in samples was not significantly different from the day 0 value, except one sample that had been stored for 30 days at room temperature yielded a significantly higher value. The assay results had a correlation coefficient of 0.922. The mean coefficient of variation for all samples was 15.7%. The slope of the curve of expected versus measured values in samples diluted two-fold nine times was 0.908, and results were linear over all dilutions.

Conclusions
The LFA for feline KIM-1 yields consistent results from stored urine samples. These characteristics will allow for KIM-1 to be measured retrospectively if immediate testing is not feasible. Within assay precision was high, and linearity over 9 logs of dilution suggests suitability for a range of subclinical and clinical kidney injuries.
Intermittent preventive treatment and malaria amongst pregnant women who give birth at the Centre Hospitalier Régional Paul Moukambi de Koula-Moutou in southeastern Gabon
Authors: Biteghe-Bi-Essone Jean Claude , Imboumy-Limoukou Roméo Karl , Ekogha-Ovono Jean Jordan , Maghendji-Nzondo Sydney , Sir-Ondo-Enguier Pater Noster , Oyegue Lydie Sandrine , Lekana-Douki Jean Bernard 
Published: November 2022

Abstract
Background
Evaluating malaria control strategies for pregnant women is essential. The objective of this study was to determine the factors influencing antenatal care (ANC) visit attendance, complete intermittent preventive treatment with sulfadoxine-pyrimethamine (IPTp-SP) and its impact on the health of pregnant women and their newborn babies living in semi-urban and rural areas of southeastern Gabon.

Methods
This transversal study was performed at the Centre Hospitalier Régional Paul Moukambi de Koula-Moutou (CHRPMK). Information regarding age, frequency of prenatal consultations, obstetric history, use of malaria control measures, use of IPTp-SP, malaria diagnostic of women and their newborns, were collected: (i): from birth registers from 1 January, 2018 to 31 December, 2019 and, (ii): a questionnaire from January to April 2020.

Results
In total, 1,851 and 323 pregnant women were included during the first and the second sub-set of study, respectively. In the first sub-set of data, the mean age was 26.18 ± 7.02 years and 96.54% (1,787/1,851) of pregnant women had attended ANC service but 54.45% had complete ANC visit attendance (at least 4 ANC). The complete ANC visit was linked with age (p < 0.001) and profession (p < 0.001). The complete IPTp-SP (at least 3 doses) was 58.87%. Complete IPTp-SP was linked to profession (aOR = 1.49, 95% CI [1.04–2.18], p < 0.001), ANC visit (aOR = 0.176, 95% CI [0.14–0.22], p < 0.034) and age (p = 0.03). Birth weight was higher for babies whose mothers had received complete IPTp-SP (p < 0,001) but the Apgar score was not influenced by the use of IPTp-SP (p = 0.71). In the second sub-set of data, the prevalence of plasmodial infection was 3.10% (95% IC [1.21–5]) and Plasmodium falciparum was responsible for 100% of infections. The prevalence of plasmodial infection was the same for all age groups (p = 0.69), gravidity (p = 0.13) and domestic control measures (p > 0.05). A low birth weight was statistically linked to the mother’s plasmodial infection (p < 0.01). Furthermore, plasmodial infection was statistically linked to premature birth (p < 0.001).

Conclusions
It was observed that attendance of women to ANC service and a complete IPTp-SP course is insufficient.
How a thrombectomy service can reduce hospital deficit: a cost-effectiveness study
Authors: Grunwald Iris Q. , Wagner Viola , Podlasek Anna , Koduri Gouri , Guyler Paul , Gerry Stephen , Shah Sweni , Sievert Horst , Sharma Aarti , Mathur Shrey , Fassbender Klaus , Shariat Kaveh , Houston Graeme , Kanodia Avinash , Walter Silke 
Published: November 2022

Abstract
Background
There is level 1 evidence for cerebral thrombectomy with thrombolysis in acute large vessel occlusion. Many hospitals are now contemplating setting up this life-saving service. For the hospital, however, the first treatment is associated with an initial high cost to cover the procedure. Whilst the health economic benefit of treating stroke is documented, this is the only study to date performing matched-pair, patient-level costing to determine treatment cost within the first hospital episode and up to 90 days post-event.

Methods
We conducted a retrospective coarsened exact matched-pair analysis of 50 acute stroke patients eligible for thrombectomy.

Results
Thrombectomy resulted in significantly more good outcomes (mRS 0–2) compared to matched controls (56% vs 8%, p = 0.001). More patients in the thrombectomy group could be discharged home (60% vs 28%), fewer were discharged to nursing homes (4% vs 16%), residential homes (0% vs 12%) or rehabilitation centres (8% vs 20%). Thrombectomy patients had fewer serious adverse events (n = 30 vs 86) and were, on average, discharged 36 days earlier. They required significantly fewer physiotherapy sessions (18.72 vs 46.49, p = 0.0009) resulting in a median reduction in total rehabilitation cost of £4982 (p = 0.0002) per patient. The total cost of additional investigations was £227 lower (p = 0.0369). Overall, the median cost without thrombectomy was £39,664 per case vs £22,444, resulting in median savings of £17,221 (p = 0.0489).

Conclusions
Mechanical thrombectomy improved patient outcome, reduced length of hospitalisation and, even without procedural reimbursement, significantly reduced cost to the thrombectomy providing hospital.
Personality-related and psychosocial correlates of sick leave days in Germany during the COVID-19 pandemic: findings of a representative survey
Authors: Hajek André , König Hans-Helmut 
Published: November 2022

Abstract
Background
The aim of our study was to assess the personality-related and psychosocial correlates of sick leave days in Germany during the COVID-19 pandemic.

Methods
We used data from a representative online-survey covering the general German adult population (data collection: mid-March 2022). We restricted our sample to full-time employed individuals aged 18 to 64 years (n = 1,342 individuals). Sick leave days in the preceding 12 months served as outcome measure. Validated and established tools were used to quantify personality characteristics and psychosocial factors (such as the Coronavirus Anxiety Scale or the De Jong Gierveld loneliness tool). Negative binomial regression models were used.

Results
After adjusting for various sociodemographic and health-related factors, regressions showed that a higher number of sick leave days was associated with lower levels of conscientiousness (IRR: 0.84, 95% CI: 0.73-0.97), higher levels of openness to experience (IRR: 1.19, 1.04–1.35), less coronavirus anxiety (IRR: 0.90, 95% CI: 0.86-0.93), and more depressive symptoms (IRR: 1.06, 1.02–1.11).

Conclusion
After adjusting for various sociodemographic and health-related factors, our study showed an association between personality-related and psychosocial factors with sick leave days. More research is required to clarify the underlying pathways.
In the presence of non-neutralising maternally derived antibodies, intradermal and intramuscular vaccination with a modified live vaccine against porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) induce similar levels of neutralising antibodies or interferon-gamma secreting cells
Authors: Aguirre Laia , Li Yanli , Baratelli Massimiliano , Martín-Valls Gerard , Cortey Martí , Miranda Joel , Martín Marga , Mateu Enric 
Published: November 2022

AbstractThe purpose of this study was to compare the immune response generated by the intramuscular and the intradermal vaccination route against the porcine reproductive and respiratory syndrome virus (PRRSV). Piglets from a seronegative and a seropositive farm were selected (n = 28 piglets per farm), and each group was divided into two groups and vaccinated after weaning with modified live vaccine Unistrain® PRRS (Laboratorios Hipra Amer, Spain) by the intramuscular (IM) or the intradermic (ID) route. For the following 6 weeks, animals were weekly bled to assess the humoral response by PRRSV-specific antibody ELISA and viral neutralisation test. At 0-, 3-, 4- and 6 weeks post-vaccination, peripheral mononuclear blood cells (PBMC) from eight animals per group were recovered to analyse cellular response by IFN-γ ELISPOT and lymphoproliferation. Serum IL-12 was also quantified by ELISA. Seroconversion was first detected 14 days post-vaccination (dpv) for both IM and ID routes, and peaked at 35 dpv (both IM groups and ID seropositive) or 42 dpv (ID seronegative). At 3 weeks after vaccination, 6/27 (22.22%) animals from negative origin had not seroconverted, and neutralising titres were significantly lower at 35 dpv compared to the seropositive origin (mean log2titres of 1.36 and 4.25 respectively) Also, it was 10 times more probable for them to have high levels of IL-12 a week after vaccination than for animals of seropositive origin. Cellular immune response analysed by lymphoproliferation and IFN-γ ELISPOT was already present at 21 dpv and until 42 dpv, with no significant differences between groups except for a higher lymphoproliferation at 35 dpv in the IM seropositive group (Kruskal-Wallis, p < 0.05). These results indicate that the intradermal route induces an immune response equivalent to the classical intramuscular route even in presence of non-neutralising maternal immunity, which in this study has proven to facilitate seroconversion after vaccination with an heterologous strain.