bluuebunny/crossref_metadata_2025_split huggingface dataset:
Real-world outcomes for Chinese breast cancer patients with tumor location of central and nipple portion
Authors: Fu Wei-Da , Wang Xiao-Hui , Lu Kang-Kang , Lu Yi-Qiao , Zhou Jie-Yu , Huang Qi-Di , Guo Gui-Long 
Published: October 2022

BackgroundThe association between tumor location and breast cancer prognosis has been controversial. We sought to explore the relationship between tumors located in central and nipple portion (TCNP) and Chinese breast cancer.Patients and methodsA total of 1,427 breast cancer patients were recruited. There were 328 cases of TCNP and 1,099 cases of tumors in the breast peripheral quadrant (TBPQ). The chi-square test was used to compare different variables between TCNP and TBPQ groups. A one-to-one propensity score matching (PSM) was applied to construct a matched sample consisting of pairs of TCNP and TBPQ groups. Kaplan–Meier curves were used for survival analysis of disease-free survival (DFS), breast cancer-specific survival (BCSS) and overall survival (OS). The Cox proportional hazards regression model was applied to identify prognostic risk factors.ResultsThe median follow-up time was 58 months. Compared to TBPQ, TCNP patients had significantly larger tumor size, more frequent metastasis to lymph nodes (LN) and more proportions of TNM stage II–III. DFS, OS and BCSS rates were markedly lower in the TCNP group as compared to the TBPQ group before and after PSM (all p &lt; 0.05). Multivariate Cox analysis showed that TCNP was an independent prognostic factor for breast cancer. Subgroup analysis indicated that for breast molecular subtypes and TNM stage II-III breast cancer, TCNP were related to worse prognosis. Multivariate logistic regression revealed that TCNP was an independent contributing factor for LN metastasis.ConclusionIn Chinese breast cancer, compared to TBPQ, TCNP is associated with more LN metastasis and poorer prognosis.
Face à la crise sanitaire : la fabrique de la continuité pédagogique
Authors: Salah Sarra Ben 
Published: October 2022

La crise sanitaire due au Covid-19 et la fermeture des établissements scolaires ont mis sur le devant de la scène la question de la continuité pédagogique. Présentée comme une interrogation nouvelle, elle avait déjà été mobilisée dans les plans de prévention et de lutte contre une pandémie grippale publiés entre 2004 et 2010. Cet article a pour ambition de proposer une analyse historique de ce concept, en mettant en perspective la manière dont l’école a réagi à la crise du Covid-19 en la comparant à des situations de crises sanitaires antérieures (celles de la H5N1 et de la H1N1). L’étude de ces plans permet de faire remonter des continuités et des discontinuités dans la définition de la continuité pédagogique. L’idée est aussi de se concentrer sur l’évolution des attentes du ministère vis-à-vis des enseignants et de leur rôle en cas de fermeture des établissements scolaires et donc de mise en place de la continuité pédagogique. Nous voulons comprendre comment l’organisation de l’école, instaurée dans l’urgence pendant le confinement de mars 2020 à mai 2020, réactualise des éléments pensés en amont par le ministère de l’Éducation nationale.
Difficulties in measuring and assessing the socio-psychological climate in the service teams of internal affairs bodies
Authors: Zlokazov Kirill , Yurenkova Vitaliya , Rozhkov Anton 
Published: October 2022

In the system of measures for the moral and psychological support of the professional activities of employees of the internal affairs bodies, the diagnosis of the socio-psychological climate is becoming increasingly important.
Along with understanding the significance of the socio-psychological climate as an important psychological phenomenon, the need for further improvement of the tools and procedures used to measure it is obvious. In addition to utilitarian reasons caused by psychometric shortcomings of the instrumentation, errors in the organization of psychodiagnostic procedures for studying it, there are reasons of a different level.
The article is devoted to the analysis of the difficulties that exist in measuring and evaluating the socio-psychological climate in the service teams of the internal affairs bodies. The authors highlight the difficulties of the methodological level, which they see in the complexity of the phenomenon of «sociopsychological climate» and the variety of scientific approaches in its description, as well as the difficulties of the instrumental level, which lie in the fact that in many ways the methods known and used by psychologists of the internal affairs bodies have lost their effect. novelties and their resistance to falsification has decreased,
which led to a decrease in the effectiveness of measuring procedures, does not allow to fully identify the reasons for the deterioration of the socio-psychological climate in the unit and predict with a high degree of probability the climate in a certain group in the long term. In the article, the authors substantiate the need to improve the practice of psychological measurement of the socio-psychological climate, describing in detail various theoretical approaches, scientific methods of cognition, particular methods of measurement and evaluation.
Using digital capabilities for information processing in modern risk management
Authors: Kharlamov A. V. , Osipov K. A. 
Published: October 2022

Aim. The presented study examines modern factors affecting the functioning of risk management, specify the requirements for information and services for retrieving and processing it to make effective management decisions aimed at minimizing or eliminating risks.Tasks. The authors specify the challenges of risk management in the context of economic instability to preserve existing positions and substantiate directions for development; determine the stages of further transformation of risk management corresponding to the strategic guidelines for the development of business structures and describe them with an emphasis on existing problems and the opportunities for solving them; investigate the nature of the increasing importance of information analysis within the framework of risk management and the necessity and possibility of attracting third-party organizations for this purpose; identify and describe changes taking place in risk management in the context of digital transformation, accompanied by changes in information analysis and the active promotion of related services by the IT sector.Methods. This study uses general scientific research methods (systems and logical approaches) and the methods of strategic and situational analysis to determine cause-and-effect relationships and describe the obtained results.Results. The authors propose an original concept substantiating the increasing importance of the joint work of business structures and their partners providing services for retrieving and processing information in the interests of risk management. Emphasis is placed on the need to protect commercial information and prevent its leakage. This concept makes allowance for current trends in the active development of the IT sector, the Internet economy, and economic security, including under economic sanctions. The proposed recommendations can serve as a basis for a comprehensive model that would make it possible to develop directions for improving the risk management system, substantiating the effective behavior of an entrepreneurial structure in the presence of economic and non-economic risks.Conclusions. The study proves that the development of a modern entrepreneurial structure increases the importance of the functioning risk management system. Factors that ensure the development of risk management and prevent it from functioning normally are identified. Based on this, recommendations for organizing effective management in this area of management activity are proposed.
Analisis dan Perancangan Sistem Informasi Catatan Penjualan dan Inventori Berbasis Web
Authors: Darsono Ivan , Stefani Kezia 
Published: October 2022

Proses dalam bisnis cukup beragam dan saling memiliki keterkaitan diantara satu dengan yang lain. Penulis merancang aplikasi inventori berbasis web untuk melacak stok barang masuk dan keluar dengan tambahan fitur pencatatan setiap transaksi yang sudah selesai dari platform e-commerce. Metode perancangan dalam penelitian ini menggunakan metode terstruktur. Penulis melakukan pembuatan Flow Map Diagram dan Data Flow Diagram.
Hasil dari penelitian ini berupa aplikasi yang mampu menambah stok barang, mencatat barang masuk dan keluar, mencatat penjualan, menambah jumlah admin, hingga menampilkan laporan stok, laporan barang masuk, laporan barang keluar, laporan penjualan, dan laporan detail barang. Melalui aplikasi ini dapat dicapai efisiensi dan kemudahan dalam memantau inventori beserta kemudahan saat mencatat transaksi yang telah selesai.
Perancangan Aplikasi Pencarian Rute Perjalanan Angkutan Kota (Angkot) di Kota bandung Berbasis Web Menggunakan Algoritma A*
Authors: Kristo Manuel , Shandi Yusup Jauhari 
Published: October 2022

Transportasi dapat membuat perjalanan menjadi mudah, membuat bepergian dari satu tempat ke tempat lainnya menjadi semakin mudah dan cepat. Transportasi umum, salah satunya angkutan kota (Angkot) muncul sebagai solusi bagi masyarakat yang tidak memiliki kendaraan untuk bepergian serta membantu mengurangi beban kemacetan di perkotaan. Untuk menentukan rute yang terpendek dapat menggunakan algoritma A* (A star). Algoritma A* dapat membuat pencarian rute yang menjadi lebih optimal. Penelitian ini merancang aplikasi pencarian rute perjalanan angkutan kota (objek penelitian di kota Bandung) berbasis web dengan menggunakan Algoritma A*.
The Influence Of Local Content Towards The Sales Of SMEs Product Through Media Of Market Place
Authors: ASI Yuli Sintha , SUNDARI Ariefah , SUSANTO Hari 
Published: October 2022

The transformation from traditional marketing into digital marketing brings changes to all aspects of human life, including economic aspects for Micro, Small and Medium Enterprises. Local SMEs fail to compete because the product is not really well-known and is not marketed digitally. The digitalization era forced SMEs to use social media for promotion. On the contrary, East Kotawaringin Regency SMEs are primarily unfamiliar with digital marketing. As a consequence, many SMEs are not able to survive. This research is carried out to help SMEs survive this Covid-19 disaster by implementing Digital Marketing to see how vital the SME sector is for regional income. It is a quantitative study to know the influence of selling products through the marketplace and how the local cultural content of the product influences the sales increase. The total population is 83 SMEs aged 18 to 25 years. The population is depreciated according to age, culinary sector and education. It obtained 31 samples. Questionnaires are distributed for data collection and are analyzed with SPSS 16. The finding of this research is that there is a correlation between local content in social media toward sales increase, as the independent shown by the t-count for each item is higher < 0.05. SMEs promote their products on social media based on local culture content linked to a local government website or other businesses such as hotels and tourist attractions.
Le trajet de la sexuation, pourquoi et comment une identité sexuée ?
Authors: Neuburger Robert 
Published: October 2022

Il est important pour chacun de se construire une identité sexuée, de se sentir exister comme homme ou femme ou autre dans son rapport à soi mais aussi reconnu, respecté, dans son rapport à l’autre ou aux autres, que ce soit dans la relation amoureuse, dans le couple, dans la famille, dans les groupes d’amis, au travail et, de façon générale, dans la société. Sont proposés six éléments essentiels qui « tressent » ce sentiment d’identité sexuée : éléments génétiques, éléments hormonaux, imitation et identification, attirances sexuelles, relations amoureuses, appartenance au groupe de pairs. Certaines défaillances lors de ce trajet et leurs conséquences sont évoquées.
Transitions de genre et psychanalyse : un nouage du réel au symbolique et à l’imaginaire
Authors: Fekete de Vàri François , Poncelet Margaux 
Published: October 2022

Bénéficiant d’un intérêt médiatique et théorique sans précédent, la situation des personnes trans interpelle. L’apport des gender studies et des sciences humaines à la psychanalyse a conduit certains auteurs et praticiens à repenser l’assujettissement et la subjectivation à travers le genre, notamment pour ce qui concerne les parcours trans. Sans prétendre épuiser la question, cet article vise à apporter une contribution à la réflexion psychanalytique sur les transitions de genre ou de sexe à partir d’un nouage du réel au symbolique et à l’imaginaire. À cette fin, nous revenons d’abord sur certains éléments de définition des transitions. Ensuite, nous examinons la relecture de la théorie psychanalytique lacanienne par Judith Butler. Cette relecture permet, d’une part, d’envisager la constitution psychique du sujet en relation au contexte social dans lequel il s’inscrit et, d’autre part, de promouvoir la force subversive de l’imaginaire face au symbolique. Enfin, nous nous penchons sur l’instance du réel, définie comme l’insaisissable qui échappe à la symbolisation. Pensées à partir du réel, les situations trans sont alors réinscrites dans la dynamique d’invention du sujet aux prises avec sa jouissance.
La stérilisation volontaire à visée contraceptive comme facteur de transformation positive chez des femmes sans enfant
Authors: Ninane Nora , Mottrie Cindy , Colman Sarah , Duret Isabelle 
Published: October 2022

En 2018, le Service de Gynécologie du CHU Saint-Pierre de Bruxelles a décidé d’ouvrir une consultation pour les femmes, sans enfant, en demande de stérilisation à visée contraceptive. Le nombre de ces demandes est en augmentation. Au moyen d’un canevas de questions semi-directives et des cartes Dixit comme « objet flottant », nous sommes allées à la rencontre de trois femmes sans enfant et stérilisées depuis six mois à un an et demi afin d’explorer les motivations et vécus à l’origine de leur choix. Les résultats mettent en évidence le poids d’événements historiques singuliers dans la décision d’inscrire corporellement leur non-maternité. Il semble que ces trois femmes se soient dirigées vers la stérilisation à un moment où elles ont eu besoin d’agir pour se réapproprier leur corps et leur vie, et de rétablir un vécu de sécurité suite à différents événements douloureux voire traumatiques. L’exploration de leurs parcours révèle que la stérilisation est l’aboutissement d’un cheminement mais aussi un processus de transformation d’une souffrance. Une fois stérilisées, elles rapportent ressentir un apaisement et un bien-être à la fois physique et psychologique, et évoquent l’émergence d’une vie différente et d’une identité plus alignée. Dans leurs histoires singulières, la stérilisation apparaît comme ayant eu un effet thérapeutique et libérateur.
Judiciariser le mariage
Authors: Monnot Aude-Cécile 
Published: October 2022

Entre 1924 et 1935, le Code pénal soviétique condamne des pratiques matrimoniales, régulières dans le droit coutumier et musulman d’Asie centrale. La criminalisation de ces pratiques ouvre un conflit social d’ampleur opposant des acteurs aux visions incompatibles du droit et de la modernité et questionnant la légitimité de l’État à intervenir dans le champ matrimonial. À partir d’archives de procès, l’article analyse le processus de socialisation des justiciables à ce droit pénal. Informés par les dispositifs d’éducation populaire des juges et des activistes politiques, les justiciables contournent le droit pour échapper à la répression ; d’autres saisissent le juge pour s’opposer aux coutumes ou instrumentalisent le recours judiciaire afin d’asseoir leurs intérêts lors de transactions matrimoniales. Ce décalage entre le pays légal et le pays réel souligne la relative fluidité des pratiques judiciaires à l’échelle des cours locales. Les juges offrent alternativement une ressource aux justiciables ou s’illustrent par des décisions s’accommodant aux exigences déterminées par le politique.
A flipped classroom experience in the context of a pandemic: Cooperative learning as a strategy for meaningful student learning
Authors: Fernández-Ferrer Maite , Espinoza Pizarro Dario 
Published: October 2022

Through an initial documentary analysis of the flipped classroom in the context of a pandemic and of the new pedagogical models based on active methodologies or pedagogies and cooperative learning, the experience presented below is part of an innovation project based on the design of cooperative activities focused on students to enhance their meaningful learning and with the aim of improving their satisfaction and motivation and thus, as a consequence, their academic performance. For the evaluation of this experience, in which 29 students from the theoretical-experimental subject of General Chemistry participated from the Technological Bases Engineering training plan of the Universidad Católica del Norte, three data collection instruments were administered based on the use of the questionnaire and the interview with the students during and at the end of the experience. The main results show high acceptance and satisfaction with the design of the innovation; an improvement in the development of teamwork competence; and a significant impact of the active methodologies and cooperative learning strategies implemented in increasing the academic performance of students.
Detection of BCL11A, HMIP, and XmnI Polymorphisms among Anemic Pregnant Women in Hospital Universiti Sains Malaysia
Authors: Abu Za'ror Yousef Saeed Mohammad , Mat Ghani Siti Nor Assyuhada , Bakar Nur Salwani , Zulkafli Zefarina , Azlan Maryam 
Published: October 2022

BACKGROUND:
Anemia is one of the most common conditions in women during pregnancy. Fetal hemoglobin (HbF) levels are usually <1.0%. There are several genetic loci that have a significant influence on HbF levels.

AIMS AND OBJECTIVES:
The aim of this study is to determine the association of HbF level and DNA polymorphism at BCL11A rs1186868, HMIP rs9376090, and XmnI rs7482144 in anemic pregnant women.

MATERIALS AND METHODS:
Blood samples were collected from 164 anemic pregnant women at Obstetrics and Gynecology Clinic, Hospital Universiti Sains Malaysia. High-performance liquid chromatography was used to determine the HbF and HbA2 levels.

RESULTS:
Multiplex amplification-refractory mutation system-polymerase chain reaction (PCR) and gap-PCR were performed for 44 samples with a high HbA2 level (>3.2%) and normal HbA2 level (≤3.2%) to detect mutation at b-globin gene cluster. Allelic discrimination for rs1186868, rs9376090, and rs7482144 was performed using the real-time PCR technique for samples with no mutation detected. The mean age of patients was 31 ± 5.9 years. The HbF and Hb levels showed a strong positive correlation (r = 0.61). Out of 22 samples, 15 mutations at the b-globin gene and no mutation at the δβ-globin gene were detected. The mean difference of HbF level of patients with and without b-globin gene cluster was 1.07 ± 0.6 and 1.79 ± 3.5, respectively. The minor allele frequency (MAF) for the studied single nucleotide polymorphisms as follows: rs1186868 (MAF = 0%), rs9376090 (MAF = 19%), and rs7482144 (MAF = 32.8%).

CONCLUSION:
In conclusion, the baseline HbF levels were unaltered by BCL11A, HMIP, and XmnI genetic polymorphisms.
Practice guidelines for the management of Helicobacter pylori infection: The Saudi H. pylori Working Group recommendations
Authors: Alsohaibani Fahad , Peedikayil Musthafa , Alshahrani Abdulaziz , Somily Ali , Alsulaiman Raed , Azzam Nahla , Almadi Majid 
Published: October 2022

Abstract
The eradication rates for Helicobacter pylori globally are decreasing with a dramatic increase in the prevalence of antibiotic resistant bacteria all over the world, including Saudi Arabia. There is no current consensus on the management of H. pylori in Saudi Arabia. The Saudi Gastroenterology Association developed these practice guidelines after reviewing the local and regional studies on the management of H. pylori. The aim was to establish recommendations to guide healthcare providers in managing H. pylori in Saudi Arabia. Experts in the areas of H. pylori management and microbiology were invited to write these guidelines. A literature search was performed, and all authors participated in writing and reviewing the guidelines. In addition, international guidelines and consensus reports were reviewed to bridge the gap in knowledge when local and regional data were unavailable. There is limited local data on treatment of H. pylori. The rate of clarithromycin and metronidazole resistance is high; therefore, standard triple therapy for 10–14 days is no longer recommended in the treatment of H. pylori unless antimicrobial susceptibility testing was performed. Based on the available data, bismuth quadruple therapy for 10–14 days is considered the best first-line and second-line therapy. Culture and antimicrobial susceptibility testing should be considered following two treatment failures. These recommendations are intended to provide the most relevant evidence-based guidelines for the management of H. pylori infection in Saudi Arabia. The working group recommends further studies to explore more therapeutic options to eradicate H. pylori.
D-finite multivariate series with arithmetic restrictions on their coefficients
Authors: Bell Jason , Smertnig Daniel 
Published: October 2022

AbstractA multivariate, formal power series over a field K is a Bézivin series if all of its coefficients can be expressed as a sum of at most r elements from a finitely generated subgroup
$G \le K^*$
; it is a Pólya series if one can take
$r=1$
. We give explicit structural descriptions of D-finite Bézivin series and D-finite Pólya series over fields of characteristic
$0$
, thus extending classical results of Pólya and Bézivin to the multivariate setting.
Methods to Evaluate COVID-19 Preventive Hygiene Programs: Observed Mask Wearing, Handwashing, and Physical Distancing Behaviors in Public Indoor Spaces in Democratic Republic of the Congo
Authors: George Christine Marie , Endres Kelly , Sanvura Presence , Williams Camille , Boroto Raissa , Lunyelunye Claude , Bisimwa Jean Claude , Timsifu Jessy , Munyerenkana Brigitte , Bengehya Justin , Maheshe Ghislain , Mwishingo Alain , Cikomola Cirhuza , Bisimwa Lucien 
Published: October 2022

ABSTRACT.
The objective of our study was to develop and test observational methods to evaluate COVID-19 preventive hygiene behaviors and physical distancing, and to evaluate the effectiveness of a government mandate on indoor fully covered mask wearing. An observational study was conducted of 4,736 individuals from April to October 2021 using 5-hour and rapid (10-minute) structured observations and spot checks to evaluate mask-wearing, handwashing, and physical-distancing behaviors, and the functionality of handwashing stations in 161 indoor public spaces across Bukavu, Democratic Republic of the Congo (DRC). Sixteen percent of individuals entering indoor public spaces were wearing a mask that fully covered their nose and mouth (fully covered mask wearing). Fully covered mask wearing was lowest inside schools (1%), universities (2%), religious establishments (22%), and health facility wards (28%). Overall physical distancing of more than 1-m inside indoor public spaces was 22%, and was lowest inside schools and religious establishments (7%). Thirty-nine percent of handwashing stations had water and a cleansing agent present. Ten percent of individuals washed their hands with a cleansing agent before entering an indoor space. Overall, fully covered mask wearing was similar for 5-hour and rapid structured observations (16% versus 15%). The odds of fully covered mask wearing was significantly greater with increased government enforcement of mask wearing in public spaces through fines (odds ratio, 2.72; 95% CI, 1.02–7.30). This study presents rigorous methods using structured observations to assess government mandates and programs on COVID-19 preventive hygiene behaviors in indoor public spaces in settings globally.