bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ectopic pregnancy risk factors in infertile patients: a 10-year single center experience
Authors: Cirillo Federico , Paladino Ilaria , Ronchetti Camilla , Busnelli Andrea , Morenghi Emanuela , Grilli Leonora , Patrizio Pasquale , Levi-Setti Paolo Emanuele 
Published: May 2022

Abstract
The present retrospective study included both in vivo and in vitro assisted reproductive technologies (ART) procedures performed from January 2009 to December 2018 at a tertiary-care Fertility Centre. The purpose was to assess the incidence of ectopic pregnancy (EP) in infertile population who undergoes ART and to identify any risk factor impacting the occurrence of EP after ART. Among 27,389 cycles, 7,352 pregnancies were achieved, of which 132 were EPs, the 1.80% (95% CI 1.5-2.1) of all pregnancies. In fresh cycles, a history of prior pelvic adhesions showed the greatest impact on the incidence of EP (aOR 2.49 95% CI 1.53 – 4.07 p < 0.001). Other factors associated with EP incidence were also identified, such as female age, basal FSH, the transfer of blastocyst embryos and difficulties during the embryo transfer procedure. In frozen cycles, the only factor influencing the incidence of EP was Anti-Mullerian Hormone (AMH) serum concentration (aOR 0.81 95% CI 0.65 – 1.00, p = 0.048). To conclude, the incidence of EP observed was comparable to that reported after natural conception. On the other hand, pre-existing risk factors, traditionally more common in infertile population, appeared to influence the incidence of EP and should thus be modified if possible.
Research on A Pixel Size Calibration Method Based on Image Matching
Authors: Feng Shuanglin , Guan Jianhe 
Published: May 2022

Abstract
Before EBI (Electron-Beam Inspection) defect detection, the pixel size of EBI equipment must be calibrated, and the calibration results will directly affect the defect detection results. Aiming at the problems of slow calibration speed, low accuracy and low robustness in EBI equipment, an automatic pixel size calibration method for EBI defect detection is proposed in this paper. It can adaptively calibrate the pixel size without standard template, and accurately calculate the pixel deviation through image matching, which successfully avoids the influence of human factors; Each calibration will automatically update the marked pattern, which can improve the success rate of image matching and facilitate full-automatic detection. The experimental results show that the proposed method can not only control the adaptive calibration of pixel size, but also speed up the detection speed and high precision. Finally, it improves the performance of the detection equipment system and enhances the robustness and adaptability of the system.
Least squares algorithm for multivariable systems: learning and prediction theory
Authors: Wang Ziming , Xing Yiming 
Published: May 2022

Abstract
In this paper, we consider the parameter estimation problem for the multivariable system. A recursive least squares algorithm is studied by minimizing the accumulative prediction error. By employing the stochas-tic Lyapunov function and the martingale estimate methods, we provide the weakest possible data conditions for convergence analysis. The upper bound of accumulative regret is also provided. Variable simulations examples are given, the results demonstrate that the convergence rate of the algorithm depends on the parameter dimension and output dimension.
Identification and Validation of a Necroptosis-related Gene based Prognostic Signature for Patients with Hepatocellular Carcinoma
Authors: Lin Junyan , Wang Zhiwei , Jiang Yonghong , Su Huihui , Yang Zhandong 
Published: May 2022

Abstract
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related death worldwide, nevertheless, its prognostic prediction remains obscure. Necroptosis is a tightly regulated form of cell death, which has been recently reported to be involved in HCC. However, the prognostic value of necroptosis-related genes (NRGs) in HCC has not been reported. In the present study, 159 NRGs of HCC subjects from the Cancer Genome Atlas (TCGA) cohort were downloaded and investigated. Of which, a total of thirty-six NRGs were identified to be significantly differentially expressed. Through univariate and multivariate Cox proportional regression analysis, four NRGs (HSP90AA1, PPIA, SQSTM1 and USP21) were found to have the excellent prognostic capacity for HCC, which could clearly divide patients into high-risk and low-risk groups. Survival analysis showed that the overall survival of high-risk patients was significantly shorter than that of low-risk patients. The independent prognostic value of necroptosis-related features was further confirmed by Cox regression analysis, and the area under the receiver operating characteristic curve of the panel comprising HSP90AA1, PPIA, SQSTM1 and USP21 was 0.807. Furthermore, the prognostic value of these NRGs was verified in another cohort of HCC patients from the ICGC database. Herein, this study shows that a novel necroptosis-related gene signature could be developed for prognostic prediction of HCC in future, which may also provide insights into the prevention and treatment of this disease clinically.
False-positive incidental lesions detected on contrast-enhanced breast MRI: Clinical and Imaging Features
Authors: Alikhassi Afsaneh , Li Xuan , Au Frederick , Kulkarni Supriya , Ghai Sandeep , Grant Allison , FREITAS VIVIANNE 
Published: May 2022

Abstract
Purpose
To identify features of the incidental MRI-detected enhancing lesions associated with false-positive outcomes, impacting patient care.
Methods
Institutional review board-approved retrospective imaging studies and patient's chart review of consecutive asymptomatic women with incidental MRI enhancing lesions detected between January-December 2018, who underwent MRI-guided biopsy. Lesions' frequency and imaging features were recorded, differentiating benign and high-risk lesions. The results were correlated with histopathology as the ground truth or uneventful follow-up of at least one year. Univariate analysis explored correlation between baseline variables and false-positive results.
Results
Two-hundred-nineteen women (median age, 49 years; range, 26–85 years) with 219 incidental MRI enhancing lesions that underwent MRI-guided vacuum-assisted biopsy during the study period formed the study cohort. Out of 219, 180 lesions (82.2%) yielded benign pathology results, 137 benign (76%) and 43 high-risk (24%) outcomes. Variables associated with true-positive results were age OR 1.05 (CI 95%, 1.02–1.08), p = 0.0015, irregular compared with oval/round mass shape lesion OR 11.2 (CI 95%, 1.6–78.4), p = 0.015, and clumped/clustered ring compared with homogeneous non-mass enhancement OR 3.17 (CI 95%, 1.38–7.28), p < 0.0066. T2-hyperintense mass-lesion correlated to the false-positive result OR 0.13 (95% CI, 0.02–0.76), p = 0.024.
Conclusion
Young patients, oval/round mass-lesion shape, T2-hyperintense mass-lesion, and homogeneous pattern of non-mass enhancement showed the strongest association with false-positive results of incidental MRI enhancing lesions. It may impact the patient's management, suggesting follow-up rather than interventional procedure when these demographic/imaging parameters are present, consequently decreasing patient's anxiety and health care costs.
Pseudocirrhosis in Metastatic Breast Cancer in a Male Successfully Treated with Leuprorelin and Anastrozole Followed by Eribulin: A Case Report
Authors: Golzarian Hafez , DO Morgan Turnow , Mariam Alaha , DO Sidra Shah , DO Syed Haq , Hawkins Christopher , Pasley Benjamin , Sree Joseph , Aujla Rajpal 
Published: May 2022

Abstract
BackgroundThere are very few studies and cases in the literature describing metastatic breast cancer in the male population, accounting for less than 1% of all cases. Of those who have been reported, the vast majority fail to survive beyond 5 years from time of diagnosis. The lack of literature in this population makes it difficult for clinicians to foresee and prepare for upcoming complications in management. One of the more serious complications in managing metastatic breast cancer is the development of pseudocirrhosis, a frequent long-term side effect of chemotherapy and/or radiation typically seen in patients with malignancy in the liver.Case PresentationWe report the case of a 48-year-old male with a completely unremarkable family, medical, and social history other than a homozygous mutation in his MTHFR gene who was diagnosed with stage IV ER/PR-positive, HER-2/neu negative, BRCA1 and BRCA2-negative breast cancer with metastasis to bone, lung, and liver who was successfully treated with a regimen consisting of radiation, Denosumab, Leuprorelin, and Anastrozole. 8 years later since initiation of treatments, he continues to survive and undergo symptomatic management of long-term side-effects of his treatments.ConclusionsTo our knowledge this is the only reported case of metastatic breast cancer with pseudocirrhosis in a male patient. It is imperative to report this unique case to help increase awareness for clinicians managing other males with breast cancer. What makes this case even more reportable is the good outcome overall as our patient remains alive and well 8 years since time of diagnosis, a relatively difficult and rare feat to achieve in end-stage breast cancer.
The physique of Olympic athletes as a reflection of human physical variation: Implications for the study of adaptive evolution and the mapping of global sports potential
Authors: Grasgruber Pavel 
Published: May 2022

Abstract
In this study, we compared the basic body dimensions (height, weight, body mass index/BMI) of 19,662 male Olympians from 159 countries competing at the Summer Olympic Games 2000-2016. We hypothesized that the average physique of national Olympic teams reflects the predominant body type of their native populations, and the knowledge of such physical differences could find practical use in creating more rational programs of sports talent selection. The results demonstrate that the mean height of men’s Olympic teams is highly correlated with the mean height of young men in their native countries (r = 0.83, p < 0.001), and the Olympic means of BMI characteristically cluster at the regional level. This geographical trend in the Olympic BMI values remarkably agrees with the documented body composition of human populations, and identifies Polynesians as the group with the most robust body build, followed by Micronesians and Melanesians. The biological validity of these results is further supported by their highly significant relationships with genetic and climatic factors. These findings suggest that the physique of Olympic athletes can be used for the study of human physical variation and evolutionary ecological rules. Based on these data, it is also possible to identify the global sports potential and the spectrum of sports in which each country has the greatest chance of international success.
DNA Sequence is Critically Involved in the Compact Assembly of Chromatin Arrays
Authors: Lyubchenko Yuri , Wang Yaqing , Stormberg Thomas , Hashemi Mohtadin , Kolomeisky Anatoly 
Published: May 2022

Abstract
The organization of the nucleosome array is a critical component of chromatin assembly as well as its function. Here we investigated the contribution of DNA sequence and internucleosomal interactions to the organization of nucleosomal arrays using Atomic Force Microscopy. We assembled nucleosomes on DNA substrates allowing for the formation of tetranucleosomes. We found that nucleosomes are capable of forming constructs with no discernible space between them, even in the case of dinucleosomes. Simulated assembly of tetranucleosomes by random placement revealed that array compaction is promoted by internucleosomal interactions. We developed a theoretical model to account for the role of DNA sequence and internucleosomal interactions in the formation of nucleosome structures. These findings suggest that the affinity of nucleosomes to the DNA sequence and the strengths of internucleosomal interactions are the two major factors defining the compactness of chromatin.
Effet d’un didacticiel pour l’apprentissage du langage SQL sur les résultats et la satisfaction des apprenants
Authors: Farza Lynda 
Published: May 2022

Dans cet article, nous présentons les résultats d’une étude sur l’effet d’un didacticiel que nous avons développé en nous inspirant des stratégies du modèle de motivation ARCS de Keller et destiné à l’apprentissage du langage SQL. Cette étude a concerné 92 étudiants de filières non informatiques répartis en deux groupes : un groupe expérimental ayant suivi l’enseignement du langage SQL en ayant recours au didacticiel que nous avons nommé SQLAlgebraCourse et un groupe contrôle qui n’a pas eu recours au didacticiel. Les résultats de cette étude ont montré que les étudiants du groupe expérimental ont eu un rendement meilleur et ont été, pour la plupart, satisfaits des avantages procurés par l’utilisation du didacticiel.
Shouting in the Kenyan Space: Can Spaceteam ESL Improve L2 Learners’ Oral Reading Fluency?
Authors: Cardoso Walcir , Waddington David , Sénécal Anne-Marie , Kiforo Enos , Anyango Linah , Karanja Dickson K. 
Published: May 2022

This study examined the effects of Spaceteam ESL, a digital shouting game, on the development of oral reading fluency (ORF) among 71 English as a second language (ESL) students in three primary and secondary schools in Mombasa, Kenya. Following a mixed-methods approach for data collection and analysis, we pre-tested and post-tested the participants on their ability to read aloud efficiently (speed) and accurately (accuracy) in three tasks: (1) phrases extracted from the game; (2) phrases not related to the game; and (3) a short anecdote. Paired-samples t-tests results revealed that, as hypothesized, participants who played Spaceteam ESL improved their ORF on measures of speed on all tasks, possibly because of the fast-paced nature of the game. However, no significant differences were observed in terms of accuracy due to a ceiling effect: the participants had already mastered the intricacies of the letter-to-sound rules of English orthography. Overall, these findings corroborate our hypothesis that some of the affordances of Spaceteam ESL (e.g., focus on speed reading, multiple and varied opportunities for practice) could contribute to the development of some aspects of oral reading fluency.
Sorption of copper(II) ions from aqueous solution by activated carbon BAU-A and coal sorbent MIU-S. The relationship between the structure of sorbents and their sorption properties
Authors: Linnikov О. D. , Rodina I. V. , Baklanova I. V. , Suntsov A. Yu. , Tyutyunnik A. P. 
Published: May 2022

Abstract
The sorption of copper(II) ions in a wide range of pH by two Russian carbon sorbents BAU-A and MIU-S was studied. Sorbents varied in structure, surface area, pH of the point of zero charge (pHZPC), and graphitization degree. The sorption studies were conducted in batch mode. The removal of copper(II) ions from a solution at pH 4, 5, 6, and 6.7 is described by the classical adsorption isotherms of Freundlich, Langmuir, and Dubinin–Radushkevich. With an increase in pH from 4 to 6.7, the sorption capacity of sorbents increases, from 0.910 to 7.163 mg/g for BAU-A, and from 0.265 to 3.307 mg/g for MIU-S. The relationship between the degree of crystallinity and the sorption properties of sorbents has been established.
Lenguas indígenas en la universidad. El caso de la enseñanza de la lengua p’urhepecha en la Licenciatura en Literatura Intercultural
Authors: Meneses Eternod Sue 
Published: May 2022

En este trabajo se presenta una serie de reflexiones a propósito de la enseñanza de la lengua p’urhepecha partir de su implementación en la Licenciatura en Literatura Intercultural de la Escuela Nacional de Estudios Superiores (ENES), UNAM Morelia. En la primera parte, se discute el estado actual de la enseñanza de las lenguas originarias como L2 en la educación superior en México, particularmente en contextos urbanos; además, se ofrece una descripción sobre la situación de la lengua y el contexto de enseñanza-aprendizaje al que hacemos referencia. En la segunda parte se expone, en términos generales y con fines de contextualización, dicha propuesta de enseñanza: sus objetivos, enfoque y algunos aspectos de la planeación. En la tercera parte se presenta una revisión crítica de los retos en la enseñanza de estas lenguas en la universidad, partiendo de tres aspectos: la situación social de las lenguas, el desconocimiento sobre los pueblos indígenas y la diferencia entre los sistemas lingüísticos en juego. En las conclusiones se plantea la necesidad de revisar las políticas institucionales en materia de lenguas indígenas e interculturalidad en la educación superior.
La nueva constitución cubana frente al nuevo constitucionalismo latinoamericano
Authors: Bobes León Velia Cecilia 
Published: May 2022

<p>Este trabajo se propone analizar la Constitución de Cuba de 2019 en el contexto del <em>nuevo constitucionalismo latinoamericano</em> (NCL) para ofrecer, desde una perspectiva comparada, algunos elementos que abonen a una reflexión sobre la política y la sociedad cubanas y sus posibles impactos sobre las relaciones entre estas dos esferas. El presente análisis compara la constitución cubana con otras 8 a través de 4 ítems: <em>1</em>) proceso constitucional; <em>2</em>) definición del Estado, principios y valores; <em>3</em>) derechos y garantías, y <em>4</em>) mecanismos de democracia directa y participación ciudadana. Los resultados de la comparación revelan semejanzas y diferencias respecto a las del NCL, que sirven de base para valorar las continuidades y rupturas, aciertos y limitaciones de la nueva Constitución de Cuba.</p><p> </p>
Why Has the Socialism of Sumak Kawsay/Good Living Failed as a New Revolutionary School of Thought in Latin America?
Authors: García-García Aurelio 
Published: May 2022

<p><strong>Abstract</strong></p><p><em>Sumak kawsay</em> socialism, or good living socialism, is one of the three schools of political thought of <em>sumak kawsay</em> which first appeared in the first decade of the twenty-first century. The idea of good living is currently re-emerging in debates on how to build a new post-pandemic world. S<em>umak kawsay</em> socialism, however, has remained on the sidelines of the political landscape and academic discussions. In its place, twenty-first century socialism has once again reappeared as the socialist proposal to create and organize a new system. This paper will analyze which practical and theoretical weaknesses and contradictions have led to the disappearance of good living socialism from political and intellectual debates. It concludes that intellectuals from different branches of socialism used <em>sumak kawsay</em>/good living as a “key symbol” to take advantage of the social, economic, political, and environmental situation in Ecuador and Bolivia in order to seize power.</p><p><strong>¿Por qué fracasó el socialismo del sumak kawsay/buen vivir como nueva corriente intelectual revolucionaria en América Latina?</strong></p><p>El socialismo <em>sumak kawsay,</em> o socialismo del buen vivir, es una de las tres corrientes políticas del buen vivir que aparecieron durante la primera década del siglo XXI. En la actualidad, el buen vivir está volviendo a emerger con fuerza en los debates sobre cómo construir un nuevo mundo pospandemia, pero el socialismo del <em>sumak kawsay </em>ha quedado al margen del panorama político y de las discusiones académicas. En su lugar, el socialismo del siglo xxi vuelve a ser la propuesta socialista para crear y organizar un nuevo sistema. En este trabajo se analizarán las debilidades y contradicciones teóricas y prácticas que han llevado al socialismo del buen vivir a desaparecer de todo debate político e intelectual, llegando a la conclusión de que intelectuales de diferentes ramas del socialismo aprovecharon la coyuntura social, económica, política y ambiental de Ecuador y Bolivia para tomar el “símbolo clave” del <em>sumak kawsay</em>/buen vivir y llegar al poder.</p>
A Agência política de mulheres negras sob a perspectiva do Mulherismo Africana: para além do ensurdecimento
Authors: Estevão de Araujo Ayni 
Published: May 2022

Este artigo visa à mobilização de alguns aspectos da teoria mulherista africana e sua pertinência para a compreensão de experiências políticas de mulheres negras no Brasil. Para tanto, apresentar-se-ão importantes pressupostos que fundam o Mulherismo Africana, bem como algumas de suas filiações teórico-metodológicas; possíveis aproximações e distanciamentos em relação a outras teorias; e, por fim, algumas reflexões acerca das agências políticas femininas negras, especialmente em solo brasileiro.
Mulheres no feminino: o poder tradicional como espaço de empoderamento das mulheres africanas
Authors: Monteiro Artemisa Odila Candé , Gomes Peti Mama , Da Silva José Manuel Mussunda 
Published: May 2022

Uma das formas do poder feminino-africano se manifesta de forma acentuada no campo da espiritualidade, tanto no mundo visível, ou seja, dos vivos, quanto no mundo invisível, o dos mortos. Este artigo faz parte de uma pesquisa em andamento, sobre o poder exercido pelas mulheres africanas e que raras vezes são consideradas ou visibilizadas como formas de poder na contramão de uma vasta literatura em que as mulheres, na sua maioria, são consideradas submissas. O interesse recai sobre práticas de tornar-se djambakus, Balobêru, nganga, Mutombe ou tchimbanda em duas realidades, a guineense e a angolana. A riqueza dos relatos das experiências de uma guineense, moradora de Ziguinchor, Senegal, com foco nas tradições ancestrais para transmitir e explicar o sagrado por intermédio da história oral, reforçam a análise da concepção do lugar destas mulheres no exercício do poder ocultado. O trabalho é de caráter teórico-qualitativo: revisão de literatura, entrevistas e história oral. O recurso da oralidade dialoga com a condição de escassez de documentos escritos sobre curandeiras, djambacus, Balobêru e nganga que se dedicam a curar. Foi entrevistada uma djambakus que transita entre Guiné-Bissau e Senegal. Os resultados apontam para a potência de mulheres na prática sagrada de cura pelo encontro de conhecimentos populares, saberes africanos tradicionais, ancestrais e do bem-estar de suas comunidades ou tabancas.