bluuebunny/crossref_metadata_2025_split huggingface dataset:
Four New Sesquiterpenoids from Zanthoxylum nitidum
Authors: Qin Feng , Li Mei‐Shan , Li Jin‐Jun , Wang Yue , Wang Ke , Zhou Jian‐Yu , Liang Dong , Wang Heng‐Shan 
Published: June 2022

AbstractZanthoxylum nitidum (Roxb.) DC., is one of Guangxi's characteristic national medicines, and is the classic Laoban medicine of Yao people “Ru Shan Hu” and Zhuang medicine “Liang Bei Zhen”. It has been used as an anti‐inflammatory, analgesic and haemostatic medicine for thousands of years. In this study, four new sesquiterpenoids (1–4), along with six previously described coumarins (5–10), were isolated from 95 % EtOH extract of Zanthoxylum nitidum. Comprehensive spectroscopic analyses (NMR and HR‐ESI‐MS) were used to elucidate the structures of these isolates. The absolute configurations of nitidumine A–D (1–4) were established by electronic circular dichroism (ECD). Their cytotoxicity of all the isolates against five cancer cell lines (T24, HeLa, MGC‐803, A549, and HepG2) was evaluated by MTT experiment and found not to be cytotoxicity.
Tyramine Derivatives Catalyze the Aldol Dimerization of Butyraldehyde in the Presence of Escherichia coli
Authors: Dennis Jonathan A. , Sadler Joanna C. , Wallace Stephen 
Published: June 2022

AbstractBiogenic amine organocatalysts have transformed the field of synthetic organic chemistry. Yet despite their use in synthesis and to label biomolecules in vitro, amine organocatalysis in vivo has received comparatively little attention – despite the potential of such reactions to be interfaced with living cells and to modify cellular metabolites. Herein we report that biogenic amines derived from L‐tyrosine catalyze the self‐aldol condensation of butanal to 2‐ethylhexenal – a key intermediate in the production of the bulk chemical 2‐ethylhexanol – in the presence of living Escherichia coli and outperform many amine organocatalysts currently used in synthetic organic chemistry. Furthermore, we demonstrate that cell lysate from E. coli and the prolific amine overproducer Corynebacterium glutamicum ATCC 13032 catalyze this reaction in vitro, demonstrating the potential for microbial metabolism to be used as a source of organocatalysts for biocompatible reactions in cells.
Water‐in‐Water Droplets Selectively Uptake Self‐Assembled DNA Nano/Microstructures: a Versatile Method for Purification in DNA Nanotechnology
Authors: Masukawa Marcos K. , Sato Yusuke , Yu Fujio , Tsumoto Kanta , Yoshikawa Kenichi , Takinoue Masahiro 
Published: June 2022

AbstractDNA is an excellent material for constructing self‐assembled nano/microstructures. Owing to the widespread use of DNA as a building block in laboratories and industry, it is desirable to increase the efficiency of all steps involved in producing self‐assembled DNA structures. One of the bottlenecks is the purification required to separate the excess components from the target structures. This paper describes a purification method based on the fractionation by water‐in‐water (W/W) droplets composed of phase‐separated dextran‐rich droplets in a polyethylene glycol (PEG)‐rich continuous phase. The dextran‐rich droplets facilitate the selective uptake of self‐assembled DNA nano/microstructures and allow the separation of the target structure. This study investigates the ability to purify DNA origami, DNA hydrogels, and DNA microtubes. The W/W‐droplet fractionation allows the purification of structures of a broad size spectrum without changes to the protocol. By quantifying the activity of deoxyribozyme‐modified DNA origami after W/W‐droplet purification, this study demonstrates that this method sufficiently preserves the accessibility to the surface of a functional DNA nanostructure. It is considered that the W/W‐droplet fractionation could become one of the standard methods for the purification of self‐assembled DNA nano/microstructures for biomedical and nanotechnology applications owing to its low cost and simplicity.
Grade 3 coronary artery perforations in chronic total occlusion‐percutaneous coronary intervention: Mechanisms, locations, and outcomes from the G3CAP Registry
Authors: Pavani Marco , Cerrato Enrico , Franzè Alfonso , Colombo Francesco , Ryan Nicola , Durante Alessandro , Bellini Barbara , Calcagno Simone , Montorfano Matteo , Gonzalo Nieves , Azzalini Lorenzo , Escaned Javier , Varbella Ferdinando ,   the Grade 3 Coronary Perforation (G3‐CAP) Registry Investigators (Cardiogroup VI Registry)
Published: June 2022

AbstractAimThe impact of Grade III coronary perforations (G3‐CP) in the setting of CTO‐PCI is not well assessed.Methods and ResultsWe reviewed 7773 CTO‐PCI and 98,819 non CTO‐PCI performed in 10 European centers: G3 perforation occurred in 87 patients (1.1%) during CTO PCI and 224 patients (0.22%) during non CTO‐PCI (p < 0.001). G3‐CP involved the CTO segment in 68% of patients and the retrograde channels in 14% of cases. In the CTO PCI group, wire induced G3‐CP (50.5% vs. 32.5%, p = 0.02) occurred predominantly when dedicated CTO tapered and highly penetrative wires were used. Intra‐procedural and in‐hospital death rates were 4.6% vs. 5.8% and 3.6% vs. 7.5% respectively for CTO PCI and non‐CTO PCI groups (p = NS). At a median follow up of 24 months, the overall mortality and MAE were respectively 7.8% and MAE 19% without difference among groups.ConclusionsWe showed similar in‐hospital and long‐term outcomes when G3 perforations occurred during CTO PCI and non CTO‐PCI.
Photothermal Oxidation of Cinnamyl Alcohol with Hydrogen Peroxide Catalyzed by Gold Nanoparticle/Antimony‐Doped Tin Oxide Nanocrystals
Authors: Inoue Haruki , Naya Shin‐ichi , Akita Atsunobu , Sugime Hisashi , Tada Hiroaki 
Published: June 2022

AbstractGold nanoparticles with different mean sizes were formed on antimony‐doped tin oxide nanocrystals by the temperature‐varied deposition‐precipitation method (Au/ATO NCs). Au/ATO NCs possess strong absorption in the near‐infrared region due to Drude excitation in addition to the localized surface plasmon resonance (LSPR) of AuNPs around 530 nm. Au/ATO NCs show thermally activated catalytic activity for the oxidation of cinnamyl alcohol to cinnamaldehyde by hydrogen peroxide. The catalytic activity increases with a decrease in the mean Au particle size (dAu) at 5.3 nm≤dAu≤8.2 nm. Light irradiation (λex >660 nm, ∼0.5 sun) of Au/ATO NCs increases the rate of reaction by more than twice with ∼95 % selectivity. Kinetic analyses indicated that the striking enhancement of the reaction stems from the rise in the temperature near the catalyst surface of ∼30 K due to the photothermal effect of the ATO NCs.
Ultrafast Time‐resolved Polarization‐dependent Investigations on the Dynamics in the 2B2 State of NO2 Molecules
Authors: Liu Yang , Sun Tian , Zhou Longxing , Zhao Yiwen , Chen Qi , Shen Xingchen , Lv Hang , Xu Haifeng 
Published: June 2022

AbstractWe perform time‐resolved polarization‐dependent study on ultrafast dynamics in the
2B2 state of NO2. A linearly‐polarized 400 nm femtosecond laser is used to resonantly pump NO2 to its first excited state
2B2, and the time‐dependent ionic yields produced via strong field ionization at 800 nm are measured under different laser polarizations. The yield ratios measured with the lasers perpendicular and parallel to each other first decrease and then increases as the wave packet evolves on the excited state, with a minimum ratio at 180 fs delay time, which can be attributed to the evolution time in the
2B2 state. The behavior of the time‐resolved ionization in elliptically polarized laser field is also investigated and discussed.
Theoretical Study on the Selective 1,2‐Reduction of α,β‐Unsaturated Ketones by Hydrogen Transfer Reaction on MgO(100)
Authors: Belelli Patricia G. , Fuente Silvia A. , Ferullo Ricardo M. 
Published: June 2022

AbstractCatalytic reduction of α,β‐unsaturated ketones with MgO has been found to improve selectivity to the desired unsaturated alcohol product. Using density functional calculations, we have studied the competitive hydrogenation of C=O and C=C bonds on Mg(100) employing two α,β‐unsaturated ketones: mesityl oxide (MO) and 2‐cyclohexenone (CH), with isopropanol (IPA) as hydrogen source. For both ketones, MgO promotes the formation of a six‐membered cyclic transition state for selective C=O reductions via a Meerwein‐Ponndorf‐Verley mechanism. Similar concerted mechanism is also possible for the C=C hydrogenation following an Eley‐Rideal mechanism, in which the IPA interacts directly with the adsorbed ketone. The activation barriers are smaller for C=O reduction because this bond is activated on MgO(100). The selective C=O reduction is more favorable for CH than for MO due to the tendency of CH to be perpendicularly oriented. The desorption energies of the unsaturated alcohol are lower than the subsequent C=C reductions.
Photoluminescent Silica Nanostructures and Nanohybrids
Authors: Gogoi Hemen , Banerjee Subhasree , Datta Anindya 
Published: June 2022

AbstractThe complicated photophysics of wide variety of defects existing in silica (SiO2) layer of nanometer thickness determines widespread photoluminescence bands of Si/SiO2 based system as well as SiO2 nanoparticles (NPs) for their applications in photovoltaic and optoelectronic devices. This review attempts to summarize different photophysical processes in pure SiO2 NPs. Moreover, these NPs also act as scaffolds for various guest molecules to perform their specific functions. Guest fluorophore molecules when trapped inside pores of SiO2 NPs exhibit a different photodynamics than free state, which opens up several important applications of hybrid SiO2 NPs in artificial photosynthesis, sensing, biology and optical fiber.
Synergistic Effects in the Activity of Nano‐Transition‐Metal Clusters Pt12M (M=Ir, Ru or Rh) for NO Dissociation
Authors: Vekeman Jelle , Wang Qing , Deraet Xavier , Bazin Dominique , De Proft Frank , Guesmi Hazar , Tielens Frederik 
Published: June 2022

AbstractThe dissociation of environmentally hazardous NO through dissociative adsorption on metallic clusters supported by oxides, is receiving growing attention. Building on previous research on monometallic M13 clusters [The Journal of Physical Chemistry C 2019, 123 (33), 20314–20318], this work considers bimetallic Pt12M (M=Rh, Ru or Ir) clusters. The adsorption energy and activation energy of NO dissociation on the clusters have been calculated in vacuum using Kohn‐Sham DFT, while their trends were rationalized using reactivity indices such as molecular electrostatic potential and global Fermi softness. The results show that doping of the Pt clusters lowered the adsorption energy as well as the activation energy for NO dissociation. Furthermore, reactivity indices were calculated as a first estimate of the performance of the clusters in realistic amorphous silica pores (MCM‐41) through ab initio molecular dynamics simulations.
Engineering Amorphous/Crystalline Structure of Manganese Oxide for Superior Oxygen Catalytic Performance in Rechargeable Zinc–Air Batteries
Authors: Zhou Zihao , Zheng Xiaoying , Liu Manna , Liu Peng , Han Shengbo , Chen Yingru , Lan Bang , Sun Ming , Yu Lin 
Published: June 2022

AbstractAlthough amorphous materials are popular in oxygen electrocatalysis, their performance requires further improvement to meet the need for rechargeable zinc–air batteries. In this work, an amorphous/crystalline layered manganese oxide (ACMO) was designed, and its unique amorphous/crystalline homogeneous structure activated its oxygen reduction activity with a positive half‐wave potential of 0.81 V and oxygen evolution activity with a moderate overpotential of 407 mV at 10 mA cm−2. Moreover, the amorphous/crystalline structure endowed ACMO with excellent stability. While employed as the air‐electrode material for rechargeable zinc–air batteries, ACMO overcame the poor cycling stability of manganese oxide and cycled stably for 1000 cycles (≈17 days) at 10 mA cm−2. Besides, it delivered a high power density of 159.7 mW cm−2 and a narrow voltage gap of 0.66 V. This work gives an insight into designing oxide materials with amorphous/crystalline structure and feasible guidance for harmonizing electrochemical activity and stability.
Cognitive perspective of osteoporosis among adults with type 2 diabetes mellitus: The Malaysian case
Authors: Abdulameer Shaymaa Abdalwahed , Sahib Mohanad Naji , Sulaiman Syed Azhar Syed 
Published: June 2022

AbstractIntroductionOsteoporosis and diabetes are highly prevalent diseases. In addition, there is increasing evidence that diabetes is a common risk factor for decreasing bone mineral density and developing osteoporosis and fractures. Data on bone abnormalities in T2DM patients appear to be contradictory and complex, and the exact underlying mechanism is still unclear. Hence, the aims of this study were to assess cognitive perspective of osteoporosis among type 2 diabetes mellitus.MethodsAn observational, cross‐sectional study design was chosen, where data were collected using a self‐report structured questionnaire including osteoporosis self‐efficacy (OSES‐M), knowledge Malay version. Quantitative ultrasound was used as prescreening tool for measuring bone health by applying T‐score.ResultsThe results showed that about 231 (51.30%) were males. The average age of the DM patients was 62.67 ± 9.24 years. Moreover, the majority of T2DM patient (343, 76.20%) had poor glycaemic control. The mean ± SD OSES‐M total score, OSES‐M Exercise subscale and OSES‐M Calcium subscale were 731.26 ± 209.83, 357.55 ± 121.23 and 373.71 ± 118.91, respectively. Overall, participants expressed a low self‐efficacy for both exercise and calcium intake experiences. In addition, a significant and positive correlation was found between OSES‐M and OKT‐M total scores (n = 450, rs = 0.471, p < .05). Also, there were significant correlations between OKT‐M subscales and OSES‐M subscales. Furthermore, significant and positive correlations were found between T‐scores and OSES‐M total score (r = .191), OSES‐M Exercise subscale (r = .209) and OSES‐M Calcium subscale (r = .124). Moreover, significant associations, differences and correlations were found out between OSES‐M with many demographic and clinical data.ConclusionOverall, participants expressed a low self‐efficacy for both exercise and calcium intake experiences. In addition, only 28.70% of the study population was found to have high OSES‐M level. Thus, self‐efficacy is important and effective determinants for gaining positive health behaviours towards osteoporosis.
Safety and efficacy of a wireless pulmonary artery pressure sensor: primary endpoint results of the SIRONA 2 clinical trial
Authors: Sharif Faisal , Rosenkranz Stephen , Bartunek Jozef , Kempf Tibor , Assmus Birgit , Mahon Niall G. , Mullens Wilfried 
Published: June 2022

AbstractAimsImplantable pulmonary artery pressure (PAP) sensors have been shown to reduce heart failure hospitalizations (HFH) in selected patients. The goal of this study was to evaluate the safety and efficacy of a novel wireless PAP monitoring system in patients with heart failure (HF).Methods and resultsThis is a prospective, multi‐centre, open‐label, single‐arm trial evaluating the safety and efficacy of the Cordella™ PA Sensor System including the comprehensive Cordella™ Heart Failure System (CHFS) in patients with New York Heart Association (NYHA) Class III heart failure with a heart failure hospitalization and/or increase of N‐terminal pro‐Brain Natriuretic Peptide (NT‐proBNP) within 12 months of enrolment. The primary efficacy endpoint was the accuracy of PA sensor mean PAP measurements, compared with fluid‐filled catheter mean PAP measurements obtained by standard right heart catheterization (RHC) at 90 days post‐implant, assessed in all patients with a successful implant. The primary safety endpoint was freedom from adverse events associated with use of the Cordella PA Sensor System through 30 days post‐implant, assessed in all patients who entered the cath lab for PA sensor implant. The PA sensor was successfully implanted in 70 patients. Equivalence between the PA sensor and RHC for mean pulmonary artery pressures was excellent with measurements confined within the equivalence bounds of −4.0 to 4.0 mmHg (mean PAP: 0.0 to 2.9 mmHg, P = 0.003). The device safety profile was excellent with 98.6% freedom from Device System Related Complications, defined as invasive treatment, device explant or death. There were no pressure sensor failures. Patients' adherence to daily measurement transmissions of PAP and vital signs was 94%.ConclusionsThis trial supports the safety and efficacy of the Cordella PA Sensor System and in conjunction with the CHFS enables comprehensive HF management in NYHA class III heart failure patients.
Association between trimethylamine N‐oxide and prognosis of patients with acute myocardial infarction and heart failure
Authors: Li Nan , Zhou Jinying , Wang Ying , Chen Runzhen , Li Jiannan , Zhao Xiaoxiao , Zhou Peng , Liu Chen , Song Li , Liao Zhiyong , Wang Xiaoqing , Yan Shaodi , Zhao Hanjun , Yan Hongbing 
Published: June 2022

AbstractAimsThis study aimed to investigate the association between trimethylamine N‐oxide (TMAO) and the prognosis and association between high‐sensitivity C‐reactive protein (hsCRP) and TMAO‐associated cardiovascular risk in patients with acute myocardial infarction (AMI) complicated by heart failure (HF).Methods and resultsA total of 985 patients presenting with AMI and HF were consecutively enrolled at the Fuwai Hospital between March 2017 and January 2020. Patients were stratified into groups according to tertiles of TMAO levels and the median hsCRP levels. The primary endpoint was major adverse cardiac events (MACE), including all‐cause death, recurrence of myocardial infarction, and rehospitalization due to HF. During a median follow‐up of 716 days, 138 (14.0%) patients experienced MACE. Cox regression analyses showed that the adjusted hazard ratio (HR) for MACE was higher in patients in tertile 3 [TMAO > 9.52 μmol/L, HR: 1.85, 95% confidence interval (CI): 1.18–2.89; P = 0.007] than in tertile 1 (TMAO < 4.74 μmol/L), whereas no significant differences were detected between the patients in tertiles 1 and 2 (TMAO = 4.74–9.52 μmol/L, HR: 0.96, 95% CI: 0.59–1.58; P = 0.874). Restricted cubic spline regression depicted an S‐shaped association between TMAO and MACE (P for nonlinearity = 0.012). In the setting of hsCRP above the median level (6.68 mg/L), per unit increase of TMAO was associated with a 20% increase of MACE risk (HR: 1.20, 95% CI: 1.05–1.37, P = 0.009); increasing tertiles of TMAO were significantly associated with a higher risk of MACE (adjusted P = 0.007 for interaction; P < 0.001 for trend across tertiles). The Kaplan–Meier analysis indicated that patients in tertile 3 had a significantly lower event‐free survival (P = 0.001) when the hsCRP level was above the median level. No similar association between TMAO and MACE was observed when the hsCRP level was below the median level.ConclusionsHigh plasma TMAO levels were independently correlated with poor prognosis in patients with AMI complicated by HF, especially in those with higher hsCRP levels. There was an S‐shaped relationship between TMAO and HR for MACE.
Non‐linear dynamic model of a two‐bodies vertical spanning wall elastically restrained at the top
Authors: Prajapati Sanjeev , Destro Bisol Giacomo , AlShawa Omar , Sorrentino Luigi 
Published: June 2022

AbstractUnderstanding the out‐of‐plane behavior of unreinforced masonry walls is crucial in seismic assessment of existing buildings. Here, the dynamic response of a vertical spanning strip wall, connected to a flexible diaphragm at the top, is investigated. Despite the simplicity of the model, two rocking rigid bodies elastically restrained at the top, the dynamic response is highly nonlinear. This behavior is due to different phenomena: when in motion the system may assume different configurations, with the transition between them due either to impacts or crack opening caused by ground acceleration. An analytical model capable to capture the complex dynamic response of the system is implemented. The equations of motion are first derived, using variational methods, then the events that the system can undergo during motion are studied. Finally, in order to show the potential of the model, some numerical exemplifications are presented applying an earthquake record and a sine pulse to the system.
Sparking creativity using extrinsic rewards: A self‐determination theory perspective
Authors: Lin Caihui (Veronica) , Shipton Helen , Teng Weili , Kitt Adam , Do Hoa , Chadwick Clint 
Published: June 2022

AbstractThe relationship between extrinsic rewards and creativity has been subject to ongoing debate within the human resource management and creativity literatures. More research on the mechanisms and boundary conditions has been called for. In this study, using 187 employee‐supervisor dyads in an electronics manufacturing company, we investigated how and when creativity‐contingent extrinsic rewards (CER) may foster creativity among manufacturing employees. Drawing on self‐determination theory, we hypothesized, and found that employee intrinsic motivation mediated the relationship between CER and employee creativity. This relationship was the strongest when employees rated their leader‐member exchange (LMX) as high. The findings reveal the important role of CER in guiding manufacturing employees' intrinsic motivation and stimulating creativity. The identification of LMX as a moderator uncovers crucial boundary conditions of this relationship. Theoretical and practical implications are discussed.
A fit-for-purpose categorization scheme for microplastic morphologies
Authors: Yu Jasmine T. , Diamond Miriam L. , Helm Paul A. 
Published: June 2022

Abstract
Microplastic categorization schemes are diverse, thereby posing challenges for cross-study comparisons. Further, categorization schemes are not necessarily aligned with and, thus, useful for applications such as source reduction initiatives. To address these challenges, we propose a hierarchical categorization approach that is “fit for purpose” to enable the use of a scheme that is tailored to the study's purpose and contains categories, which, if adopted, would facilitate interstudy comparison. The hierarchical categorization scheme is flexible to support various study purposes (e.g., to support regulation and toxicity assessment) and it aims to improve the consistency and comparability of microplastics categorization. Categorization is primarily based on morphology, supplemented by other identification methods as needed (e.g., spectroscopy). The use of the scheme was illustrated through a literature review aimed at critically evaluating the categories used for reporting microplastic morphologies in North American freshwater environments. Categorization and grouping schemes for microplastic particles were highly variable, with up to 19 different categories used across 68 studies, and nomenclature was inconsistent across particle morphologies. Our review demonstrates the necessity for a “fit for purpose” categorization scheme to guide the information needs of scientists and decision-makers for various research and regulatory objectives across global, regional, and local scales. Integr Environ Assess Manag 2023;19:422–435. © 2022 SETAC