bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mass phenomena from a cerebellopontine angle arachnoid cyst: case report
Authors: Apostolakis S. , Karagianni A. , Mylonakis I. , Vlachos K. 
Published: August 2022

Introduction. Arachnoid cysts are benign lesions comprising about 1 % of all intracranial space occupying lesions. The majority are asymptomatic, while surgical intervention, consisting of fenestration, is suggested in the presence of mass phenomena.The aim of the study – to present the case of a patient with arachnoid cysts in the cerebellopontine angle and its treatment.Materials and methods. A 53‑years old female patient was referred to our Department of Neurosurgery for the surgical management of a cerebellopontine angle mass. The patient reported tingling sensation and causalgia of her left hemiface, dysarthria, hoarseness, difficulty swallowing solid food and liquids, tinnitus and pain distributed along the ophthalmic branch of the trigeminal nerve.Results. The patient was subjected to retrosigmoid craniotomy with fenestration of the cyst and concurrent placement of a Torkildsen shunt. No complete resection of the capsule of the cyst was attempted, due to its tight adhesions to the adjacent structures. Postoperatively, there was an improvement in the dysarthria and swallowing of the patient.Conclusions. Cerebellopontine angle cystic lesions while histologically benign, may become clinically apparent due to compression of adjacent structures. Simple fenestration of the cyst may be sufficient for the remission of symptoms.
Staged radiosurgery of large brain metastasis with mass effect and brain dislocation: case report
Authors: Ilyalov S. R. , Parshunina A. M. , Kvashnin K. M. , Medvedeva K. E. , Baulin A. A. , Lepilina O. G. 
Published: August 2022

Introduction. Currently, one of the effective methods of treatment of intracranial metastases is stereotactic radiosurgery. The main factors limiting its use are the size (volume) of the tumor or the location of the metastasis in critical proximity to radiosensitive brain structures, such as the optic pathways, thalamus, brain stem, due to the high risk of developing local radiation necrosis. To reduce the risk of adverse radiation effects, hypofractionated radiotherapy by linac or staged Gamma Knife radiosurgery is used. However, large brain metastases that cause dislocation of the brain midline structures are traditionally considered an object for surgical excision, the main purpose of which is to eliminate the mass effect caused by the tumor.The objective of the publication: to demonstrate a case of successful application of staged Gamma Knife radiosurgery of large brain metastases accompanied by brain compression and dislocation.Materials and methods. Patient, 38‑year-old, with right-sided hemiplegia (0 score) and large (Ø = 3 cm, V = 12.9 cm3) breast cancer metastasis in the deep site of the left hemisphere, accompanied by severe perifocal edema and braindislocation (midline shift up to 15 mm). The treatment was carried out by Gamma Knife in two stages with an interval of 1.5 months.Results. As a result, not only a complete regression both of the perifocal edema and midline shift were noted, but also a significant decrease of the tumor volume and dramatical improvement in the patient’s neurological status already in the interval between the stages of radiosurgery: restoration of active movements in the right limbs (up to 4 score).Conclusion. This case demonstrates the possibility of effective and safe non-invasive treatment of large brain metastases accompanied by brain compression and dislocation, which makes it possible to achieve regression of the mass effect and improve the neurological quality of life of cancer patients.
Comparison of two different doses of dexmedetomidine in attenuation of haemodynamic response during endotracheal extubation
Authors: Phalgune Deepak Sadashiv , Tamboli Asir , Jana Joyshankar 
Published: August 2022

The data in the published literature on the use of dexmedetomidine in various dosages during extubation from India is modest. We have compared the effectiveness of intravenous dexmedetomidine 0.5 µg/Kg body weight and 0.75 µg/Kg body weight during endotracheal extubation. Seventy-four patients aged more than 18 years posted for elective surgery under general anaesthesia were included in this randomised double- blind controlled study. Group D1 and Group D2 patients received 0.5 µg/Kg and 0.75 µg/Kg body weight intravenous dexmedetomidine respectively. The primary outcome measures were to compare haemodynamic parameters, whereas secondary outcome measures were to compare extubation quality, and post-extubation sedation. The mean heart rate at reversal, and after endotracheal extubation was considerably elevated in group D1 as compared to D2. The mean systolic blood pressure, diastolic blood pressure and mean arterial pressure after endotracheal extubation were considerably elevated in group D1 as compared to D2. The mean respiratory rate at reversal, and after endotracheal extubation were considerably elevated in Group D1 as compared to Group D2. The mean sedation score after endotracheal extubation was considerably elevated in Group D2 as compared to Group D1. The haemodynamic parameters were better in Group of patients who received intravenous dexmedetomidine 0.75 µg/Kg body weight as compared to Group of patients who received dexmedetomidine 0.50 µg/Kg during endotracheal extubation.
Tocilizumab as a breakthrough in the cytokine storm of COVID-19 pneumonia- Case series in the intensive care unit
Authors: Gulabani Michell , Chauhan Richa , Saxena Ashok Kumar 
Published: August 2022

Tocilizumab (TCZ) is a promising treatment for management of COVID-19 pneumonia amid many controversies linked to its potential benefit. The exact time for administration of the drug to avail maximum clinical benefit is still unclear. We present a case series in which three patients with severe COVID 19 (respiratory rate of more than 30/min, breathlessness and hypoxia with Spo2&#60;92% on room air) and without any pre-existing co-morbid conditions were administered Inj TCZ intavenously based on increasing levels of inflammatory markers (CRP and IL6), worsening dyspnea and radiographic evidence of COVID-19 deterioration. They were admitted in our Intensive care unit (ICU) nearly 7-10 after symptom onset. Their inflammatory markers were raised with CRP&#62;75 mg/dl, IL-6 &#62; 200 pg/ml and ABG depicted falling trend in Pao2/Fio2 ratio despite adequate ventilation. These patients received TCZ nearly 9to 14 days of ICU stay after excluding secondary bacterial and fungal infections (sputum, urine and blood culture) as their inflammatory markers increased suddenly during the late phase of the disease. Their liver and kidney functions were acceptable and no neutropenia or thrombocytopenia was ensured. Their inflammatory markers improved significantly post intervention and they weaned from non-invasive ventilation, transferred from the intensive care unit to the ward and later discharged in 20-25 days from the hospital.Therefore, we would like to emphasize consideration of TCZ in worsening critically ill COVID-19 patients as a pharmacological modality even during late phase of the disease as a means to improve oxygenation, avoiding mechanical ventilation and subsequent morbidity and mortality. COVID 19 is a dynamically evolving disease and new treatment modalities at the different stages of the disease may yield benefits in certain sub-groups of patients.
Paediatric airway and challenges during covid era
Authors: Gogoi Daisy , Dutta Anup , Talukdar Pranjit 
Published: August 2022

Pediatric airway brings some unique challenges to anesthesiologist. Anaesthesiologists are at particularly high risk of being exposed to Covid cases because airway management, particularly tracheal intubation, positive pressure ventilation through a mask, and management of tracheostomy tubes, causes widespread aerosolization of the virus. But these cases cannot be deferred. The aim is to present a case series of difficult pediatric airway scenarios managed successfully with different techniques and airway gadgets during COVID times taking all safety precautions. The following cases were managed successfully with appropriate airway techniques from the period of April 2020 to September 2021 in our institute.First case series of Tracheobronchial foreign bodies removal using controlled ventilation. Secondly Juvenile onset recurrent laryngeal papillomatosis for excision under coblation, one case managed by tubeless anesthesia and other by intubation using videolarygoscopy. Third case scenarios of Laryngeal web for excision with MLS scissor managed by LMA followed by tracheostomy. These airway related complications during COVID era, not only had logistic problems but also to optimize and work in a coordinated way with ENT surgeon in the common airway is a challenging task. These three case scenarios of pediatric airway during COVID times, were successfully managed with appropriate airway gadget suitable for each case without any complications.
desenvolvimento profissional dos professores de matemática selecionados no programa OBMEP na escola
Authors: Costa Roberta , Prata-Linhares Martha Maria 
Published: August 2022

O objetivo deste estudo é levantar a produção intelectual da área da Educação relacionada ao Programa OBMEP na Escola e o desenvolvimento profissional docente em presente na Biblioteca Digital Brasileira de Teses e Dissertações (BDTD) e nos anais das reuniões nacionais da Anped no período de 2015 a 2021. É um levantamento bibliográfico inicial com abordagem qualitativa. Das 199 publicações extraídas da Anped, nenhuma delas tem como descritor o Programa OBMEP na Escola. Na BDTD encontramos uma dissertação. Os resultados indicam ausência e necessidade da promoção de estudos relacionados ao desenvolvimento profissional dos professores de Matemática e o Programa OBMEP na Escola.
Direitos humanos e diversidade
Authors: Silva Santos Marinna , Martinelli Borges de Oliveira Anelise 
Published: August 2022

Desde o século XIX, a educação é considerada um direito humano integrante do rol de direitos sociais. Tal conquista, entretanto, por vezes se restringe à expansão da escolarização e à afirmação da igualdade entre estudantes. A tentativa de homogeneização, característica de nossa cultura escolar, invisibiliza a diversidade no ambiente escolar. Assim, o presente trabalho pretende apresentar a Educação em Direitos Humanos como alternativa viável para desconstrução da cultura escolar vigente que não se atenta às marcas identitárias dos estudantes. Para tanto, nossa pesquisa será realizada a partir da análise dos autores AZANHA (1991); JULIA (2001) e CANDAU (2012).
PALAVRAS-CHAVE: Educação. Direitos Humanos. Cultura Escolar. Diversidade
PENGARUH MODEL PEMBELAJARAN TEAM GAME TOURNAMENT TERHADAP HASIL BELAJAR TAJWID
Authors: Wardani Dian Kusuma , Mukarromah Niswatin 
Published: August 2022

Abstract: The learning model determines the results achieved by student learning. The use of inappropriate models will make students passive in the learning process. Team Games Tournament (TGT) is a collaborative model that triggers student collaboration and creativity. This study aims to test the effectiveness of the TGT model in learning recitation of the second grade students of Wustho Madin At-Takmiliyah An-Najiyah 1 Jombang. This study uses the entire population. The method used is quasi-experimental. The data analysis method for this study used the Wilcoxon paired pair test. The results of this study indicate that the use of the TGT learning model has a significant effect on the learning outcomes of class II Wustho students.Keywords: Team-Games Tournament; tajweed; learning achievement; Abstrak: Model pembelajaran menentukan hasil yang dicapaian pembelajaran siswa. Penggunaan model yang kurang tepat akan membuat siswa pasif dalam proses pembelajaran. Team Games Tournament (TGT) merupakan model kolaboratif yang memicu kolaborasi dan kreativitas siswa. Penelitian ini bertujuan untuk menguji efektivitas model TGT pada pembelajaran tajwid pada siswa kelas II Wustho Madin At-Takmiliyah An-Najiyah 1 Jombang. Penelitian ini menggunakan seluruh populasi. Metode yang digunakan adalah quasi-eksperimen. Metode analisis data untuk penelitian ini menggunakan uji pasangan berpasangan Wilcoxon. Hasil penelitian ini menunjukkan bahwa penggunaan model pembelajaran TGT berpengaruh signifikan terhadap hasil belajar siswa kelas II Wustho.Kata Kunci: Team-Games Tournament; tajwid; hasil belajar
Decompression without Fusion for Lumbar Spinal Stenosis at a Single Mobile Segment in Adults with Ankylosing Spondylitis
Authors: Netsanet Rahwa , Look Nicole , Koshak Christina , Patel Vikas 
Published: August 2022

Case:
This report details the cases of 2 older male patients with ankylosing spondylitis (AS) who presented with lumbar spinal stenosis at a single residual mobile segment and were treated with decompression without fusion. Both patients presented with severe symptoms in their lower limbs and opted to proceed with surgery.

Conclusion:
With autofusion above and below their single, stable mobile segment, decompression without fusion was a safe and effective procedure. A Coflex device was implanted in 1 patient. After successful surgery, both patients experienced significantly decreased symptoms.
Delayed Hypoglossal Nerve Palsy After Halo-Vest Immobilization in a Patient With C1-C2 Tuberculosis
Authors: Basu Saumyajit , Gohil Kushal 
Published: August 2022

Case:
A 48-year-old man presented with neck pain and torticollis without any neurodeficit. He was diagnosed with C1-C2 tuberculosis with left C1-C2 joint destruction and was immobilized with a halo vest and started on antitubercular treatment (ATT). At the 3-month follow-up, he presented with left hypoglossal nerve palsy (HNP). He responded to ATT with complete healing of C1-C2 lesion and good correction of deformity but persistent left-sided tongue deviation at the 2-year follow-up.

Conclusion:
HNP may occur as a complication of conservative management of craniovertebral junction tuberculosis (CVJ TB). Careful neurological assessment and monitoring must be performed while correcting deformities in CVJ TB using halo-vest immobilization.
Heat-Treated Osteochondral Allograft and Autologous Chondrocyte Implantation for a Large Osteochondral Defect
Authors: Narita Yasushi , Miyazaki Masashi , Hirakawa Masashi , Matsuda Shogo , Nagashima Yu , Tsumura Hiroshi 
Published: August 2022

Case:
A 21-year-old man presented with knee pain secondary to tibial plateau malunion and an osteochondral defect 1 year after open reduction and initial fixation. Two-stage reconstruction with transplantation of a bulk heat-treated osteochondral allograft and an autologous chondrocyte implantation was performed.

Conclusion:
This technique may be a good choice for large defects in the articular cartilage in cases of tibial plateau malunion. It may be a viable alternative for defect reconstruction, resulting in favorable early clinical, functional, and radiological outcomes.
Osteochondral Allograft Reconstruction of a Pediatric Distal Humerus Fracture with Articular Bone Loss
Authors: Norrell Kirsten , Stanislav Derec , Sinclair Micah , Tougas Caroline 
Published: August 2022

Case:
A right hand dominant 10-year-old girl presenting with an open right distal humerus fracture dislocation involving complete medial column bone loss and a >50% trochlea defect was reconstructed with a size-matched, fresh distal humerus osteochondral allograft. Successful bony integration and functional elbow range of motion were achieved.

Conclusion:
A paucity of literature exists to guide the treatment of pediatric distal humerus fractures with significant bone loss. Despite complications associated with osteochondral allografts, they provide a reasonable treatment option to preserve elbow motion in children with unreconstructible intra-articular distal humerus fractures to avoid arthrodesis.
Exposure of Pedicle Screws due to Chronic Vertebral Erosion by Tracheostomy Tube Cuff Balloon
Authors: Gupta Arjun , Harbison R. Alex , Sponseller Paul D. 
Published: August 2022

Case:
We report a patient with permanent tracheostomy in the context of muscular dystrophy presented for pneumonia. On bronchoscopy, a pedicle screw was seen penetrating the trachea. Computed tomography revealed significant anterior erosion of the T1-T3 vertebrae due to chronic pressure injury from the tracheostomy cuff, exposing pedicle screws implanted >10 years earlier. The patient was fitted for a custom low-pressure cuff. No further sequelae developed for 4 months.

Conclusion:
To the best of our knowledge, this is the first case of exposed spinal fusion instrumentation due to chronic vertebral erosion. Early sagittal imaging and the use of low-pressure cuffs may help prevent this complication.
POTENSI PENGEMBANGAN HANJELI (Coix lacryma-jobi L.) DAN JEWAWUT (Setaria italica) MENDUKUNG DIVERSIFIKASI PANGAN LOKAL / Hanjeli (Coix lacryma-jobi L.) and Millet (Setaria italica) Development Potential to Support Local Food Diversification
Authors: Suarni Suarni 
Published: August 2022

<p>The benefits of hanjeli grain are that they include protein 14.8 g/ 100 g, fat 4.g/100 g and Fe minerals 6 mg/100 g, whereas millet seeds contain protein 12.0 mg/100 g, dietary fiber 8.2%, and phenolic 0.03% to 3.0% at a level that is significantly greater than other cereals. The potential nutritional and functional components of these alternative cereal commodities make them a good food source to support local food diversification, and even serve as functional food items. The development potential demands of high yielding varieties that is superior to local varieties. Appropriate farming technology and post-harvest processing are required to increase yield. The final product is preferred by consumers on organoleptic tests (willingness to accept-WTA) of various circles, has a selling value and is affordable (willingness to pay-WTP), along with adequate nutritional content, especially the bioactive functional components must be preserved through adequate processing. It is possible to bring attention to hanjeli and millet cereals as neglected foodstuffs if they are packaged correctly, so that a quality and aesthetically pleasing final product is achieved.</p><p>Keywords: Hanjeli, millet, food diversification, potential</p><p> </p><p><strong>Abstrak</strong></p><p>Biji hanjeli mengandung protein 14,8 g/100 g, lemak 4,9 g/100 g, mineral Fe 6 mg/100 g, sedangkan biji jewawut mengandung protein 12,0 mg/100 g, serat pangan 8,2%, fenolik 0,03-3% relatif lebih tinggi dibanding serealia lainnya. Potensi komponen nutrisi dan fungsional pada komoditas serealia alternatif tersebut menjadikannya sumber pangan yang layak dikembangkan untuk mendukung diversifikasi pangan lokal, bahkan dapat berfungsi sebagai bahan produk pangan fungsional. Potensi pengembangan memerlukan varietas unggul baru (VUB) yang memiliki sifat yang lebih baik dibanding varietas lokal. Untuk meningkatkan produksi kedua komoditas memerlukan teknologi budi daya dan penanganan pascapanen yang tepat. Penanganan pengolahan yang memadai diperlukan untuk memperoleh produk akhir yang disukai konsumen dari berbagai kalangan, tingkat penerimaan melalui uji organoleptik memenuhi willingness to accept (WTA), memiliki nilai jual dengan harga yang terjangkau (willingness to pay-WTP), disertai kandungan gizi yang memadai, terutama komponen fungsional bioaktif. Dikemas secara higienis akan diperoleh produk hanjeli dan jewawut yang berkualitas dan menarik sehingga kedua serealia ini potensial dipasarkan dan dikembangkan mendukung diversifikasi pangan.</p><p>Kata Kunci: Hanjeli, jewawut, diversifikasi pangan, potensi</p>
Differentiated Approaches to the Choice of Timing of Surgical Treatment for Intrathoracic Lymph Node Tuberculosis in Children during Increasing Incidence of Multiple Drug Resistant Tuberculosis
Authors: Gubkina M. F. , Petrakova I. Yu. , Bagirov M. A. , Yukhimenko N. V. , Khokhlova Yu. Yu. , Sterlikova S. S. 
Published: August 2022

The objective: to develop differentiated approaches to the choice of timing of surgical treatment of intrathoracic lymph node tuberculosis (ITLNTB) in children during the increasing incidence of multiple drug resistant tuberculosis (MDR-TB).Subjects and Methods. 52 patients of 2-12 years old had their intrathoracic lymph nodes removed at different stages of anti-tuberculosis therapy. All children had massive (more than 10-15 mm) conglomerates in their intrathoracic lymph nodes. Additionally to changes in intrathoracic lymph nodes, 12 people had active tuberculous changes in the lungs or bronchial tuberculosis.Results. 5 patients were operated before chemotherapy, 35 patients after 2 months of treatment, and 12 patients underwent surgery afterwards. The elective surgery was performed in 51 children, and 1 child had surgery before the start of chemotherapy due to vital indications (the threat of breakthrough of caseous masses into the trachea).Planned surgical treatment in children with tuberculosis of intrathoracic lymph nodes should be carried out within the following timing: before the start of anti-tuberculosis therapy in the absence of clinical, laboratory and radiological signs of the disease being active; as soon as possible from the start of chemotherapy (it is enough to focus on the results of the first CT control after 2 months of treatment (there should be no tendency to involution of pathological changes) in the presence of minimal signs of tuberculosis activity). The choice of timing of planned surgical treatment is individual and determined by the timing of stabilization of pulmonary changes or the cure of bronchial tuberculosis (after 6, 9, 12 months) in patients with newly diagnosed active tuberculosis of intrathoracic lymph nodes in combination with lung and/or bronchial lesions. The development of life-threatening complications is an absolute indication for emergency surgery.
Endoscopic Diagnosis of Bronchial Tuberculosis in Pulmonary Tuberculosis Patients with Different HIV Status
Authors: Sinitsyn M. V. , Bykov S. V. , Reshetnikov M. N. , Aralova I. S. , Antipov A. G. 
Published: August 2022

The objective: to compare the effectiveness of endoscopic diagnosis of bronchial tuberculosis in pulmonary tuberculosis patients with different HIV status.Subjects and Methods. The data obtained during tracheobronchoscopy in 371 respiratory tuberculosis patients from 2018 to 2020 were retrospectively studied. The indication for bronchoscopy was the presence of clinical and radiological symptoms characteristic of bronchial tuberculosis in a pulmonary tuberculosis patient. All patients were divided into two groups: HIV+ and HIV-.Results. In pulmonary tuberculosis patients with clinical and radiographic findings characteristic of bronchial tuberculosis, the frequency of endoscopic confirmation of bronchial tuberculosis in HIV+ Group was 57/71 (80.3%), in HIV- Group – 138/300 (46.0%), p < 0.01; χ2 = 27.06.Most often, in HIV-positive patients, the infiltrative form of bronchus tuberculosis was detected – 27 (47.4%) patients, and the fistulous form – 23 (40.4%) patients, bronchial lesions in HIV negative tuberculosis patients were mainly infiltrative – 94 (68.1%) or ulcerative – 24 (17.4%).The frequency of microbiological detection of the causative agent of tuberculosis increased when bronchobiopsy was performed versus sputum microscopy, especially in HIV negative tuberculosis patients (from 39.9 to 91.3%), and among HIV positive patients from 15.7 to 47.4%.