bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accounting and analysis of operating expenditure of agricultural enterprises
Authors: Pylypenko Kateryna , Koval Svetlana , Kucherenko Mykola 
Published: January 2022

The subject of research is the theoretical and practical aspects of accounting and analysis of operating costs of agricultural enterprises, their impact on financial results, as well as proposals for optimization. The purpose of the article is to identify and summarize the features of accounting and analysis of operating costs of agricultural enterprises, establishing their impact on financial performance and development of optimization proposals. The methodological basis of the article is a monograph, system-structural analysis and synthesis, accounting, economic and statistical methods. The results of the article. It is established that the accounting of operating expenses is regulated by the NP (S) BU and its relevant forms. Their information is the main basis for their comprehensive analysis. Its implementation allowed to determine their constant increase and identify its factors. It was found that the cost of production, administrative costs, marketing costs and others are of paramount importance in the structure of operating expenses. They are also the ones who significantly shape the financial results of agricultural enterprises. Therefore, it is their optimization that increases profits as the main financial result. Field of application of results. The results can be used in higher education institutions, agricultural enterprises and other agribusiness entities. Conclusions. It is established that in the structure of operating costs the largest share is the cost of production, labor costs, administrative costs and marketing costs. They have been characterized by a significant increase over the last three years due to the constant growth of their components. Therefore, their optimization, as shown by the analysis of operating activities of agricultural enterprises, is based on reducing the cost of production by increasing the productivity of resources and labor, as well as reducing administrative costs due to improved organization of business and production processes. Changes in operating expenses are a factor influencing the dynamics of financial performance of economic entities, namely gross profit and profit from operating activities.
Pengaruh Motivasi Dan Kompetensi Terhadap Kinerja Perawat Di Instalasi Paviliun Tandang Pada Rumah Sakit Umum Daerah Kabupaten Sumedang
Authors: Kurniasih Nining 
Published: January 2022

ABSTRAK
Temuan dari hasil penelitian ini membuktikan seluruh hipotesis penelitian ini yaitu terdapat pengaruh motivasi kerja dan Kompetensi, baik secara simultan maupun secara parsial. Pengaruh yang ditimbulkan dari hasil penelitian menunjukkan arah yang positif, yang berarti bahwa motivasi kerja yang lebih baik dan adanya Kompetensi yang baik akan meningkatkan kinerja Perawat, Motivasi perawat merupakan suatu bentuk kesediaan untuk berusaha keras mencapai tujuan organisasi dengan memperhatikan usaha memuaskan beberapa kebutuhan, serta upaya untuk memperbaiki dan membentuk pengetahuan, sikap dan perilaku karyawan sehingga karyawan tersebut secara sukarela berusaha bekerja secara kooperatif dengan para karyawan lainnya untuk meningkatkan kinerjanya.
Pengaruh motivasi kerja terhadap kinerja perawat, untuk melihat apakah ada pengaruh antara variabel motivasi dan kinerja perawat, hal perlu dilakukan adalah menentukan hipotesis, berdasarkan hasil perhitungan diperoleh H0 ditolak dan H1 diterima. Artinya terdapat pengaruh antara motivasi dan kinerja perawat. sedangkan besarnya pengaruh motivasi terhadap kinerja perawat artinya motivasi naik, maka kinerja akan meningkat.
Pengaruh kompetensi terhadap kinerja Perawat, hasil perhitungan H0 ditolak dan H1 diterima. Artinya terdapat pengaruh antara kompetensi dan kinerja Perawat. untuk melihat pengaruh motivasi dan kompetensi terhadap kinerja Perawat secara simultan (gabungan), besarnya R Square dapat digunakan untuk melihat besarnya pengaruh motivasi dan kompetensi terhadap kinerja perawat secara bersama-sama atau simultan. Besarnya pengaruh motivasi dan kompetensi terhadap kinerja Perawat secara bersama-sama dipengaruhi faktor lain, yaitu, pelatihan, kompensasi dan lain-lain.
Hasil perhitungan korelasi antar variabel yang diteliti dengan menggunakan program bantuan software SPSS diketahui nilai korelasi antar variabel motivasi dan kompetensi terlihat hubungan antar variabel sangat kuat. dan korelasi kedua variabel bersifat signifikansi, dari hasil perhitungan koefisien jalur yang diperoleh, maka dapat terlihat besarnya pengaruh variabel yang dihipotesiskan. variabel-variabel yang di luar variabel penelitian mempengaruhi terhadap kinerja Perawat.

Kata Kunci : Motivasi, Kompetensi dan Kinerja Perawat
TASLAMPOT (Tanaman Hias Dalam Pot) Pembudidayaan Tanaman Hias Dimasa Pandemi Covid 19
Authors: Anisa Prihandini Ragil , Kurniawan Afif , Dwi Putra Risal , Tampubolon Okida Putra , Siregar Karlstaine Baginda Soaloon , Kadafi Abdul Rahman 
Published: January 2022

Kebutuhan akan tanaman hias mengalami peningkatan. Selain kesan segar, keberadaan tanaman hias bisa menyehatkan tubuh karena tanaman yang ada mengeluarkan oksigen yang diperlukan manusia. Tanaman hias berperan menghasilkan oksigen dan menghiasi rumah atau pekarangan tempat tinggal kita, akan tetapi berkhasiat obat untuk kesehatan tubuh manusia. Taslampot dapat menggunakan tempat berupa pot plastik dan pot tanah liat. Media tanam taslampot tentunya memiliki kelebihan dan kekurangan. Kelebihan taslampot, yaitu praktis, tidak memerlukan banyak media dan harga relatif murah. Kelemahannya, yaitu jumlah dan jenis tanaman hias yang dapat ditampung terbatas. Taslampot dapat dijadikan solusi praktis dalam keterbatasan lahan pertanian. Keterbatasan lahan tidak menghentikan niat seseorang untuk bercocok tanam. Sebagian ibu rumah tangga tetap melakukan hobi berkebun walaupun ruang yang tersedia tidak cukup luas.
Analisis Penyebab Emiten Delisting Serta Akibat Yang Didapatkan Para Pemegang Saham
Authors: Apandy Puteri Asyifa Octavia 
Published: January 2022

Pasar modal dapat diartikan sebagai pasar yang menyediakan fasilitas untuk penerbitan dan perdagangan efek keuangan seperti saham. Setiap emiten pasti memiliki tujuan untuk terus maju, tetapi dalam kehidupan nyata ada beberapa emiten yang akhirnya di delisting. Berdasarkan hal tersebut, penulis bertujuan untuk menganalisis penyebab emiten yang di delisting dan mengetahui apa akibatnya bagi pemegang saham. Penelitian ini menggunakan pendekatan kualitatif deskriptif. Dapat disimpulkan bahwa penyebab emiten delisting adalah karena emiten tersebut telah melanggar aturan, terjadi kondisi bisnis yang negatif, kebangkrutan, tidak dapat menghasilkan pendapatan operasional dan keuangan emiten yang tidak stabil. Akibatnya bagi para pemegang saham pertama dapat menerima semua dana kembali, yang kedua dapat menerima beberapa persen (%) dari dana, yang ketiga akan kehilangan semua dana mereka atau dana tidak akan kembali sepenuhnya, jadi disarankan untuk berhati-hati. dalam memilih emiten untuk berinvestasi.
Kata Kunci: Penghapus Daftar; Emiten; Saham; Pemegang Saham.
ФОРМУВАННЯ СОЦІАЛЬНО-ПСИХОЛОГІЧНОГО КЛІМАТУ В ПРОЦЕСІ УПРАВЛІННЯ ПЕРСОНАЛОМ ДОШКІЛЬНОГО НАВЧАЛЬНОГО ЗАКЛАДУ ЯК СПОСІБ ПІДТРИМКИ ПРОДУКТИВНОСТІ ПРАЦІ ПЕДАГОГІВ
Authors: Бутиріна М. В. , Борщевицька Н. М. , Трунова Н. А. 
Published: January 2022

ORCID 0000-0003-0867-1119
У статті досліджено та визначено поняття «соціально-психологічний клімат» як загальний емоційно-динамічний настрій колективу, який передбачає створення здорової творчої обстановки в колективі з високими результатами праці і перебуває в прямій залежності від того, який стиль управління обрано керівником. Авторами виокремлено фактори, що впливають на формування соціально-психологічного клімату в колективі, такі як: спрацьованість, дисципліна, адекватна самооцінка і взаємоповага.
Досліджено вплив соціально-психологічного клімату на продуктивність праці педагогів: позитивний соціально-психологічний клімат підвищує настрій людини, її творчий потенціал, позитивно впливає на бажання працювати в даному колективі, застосовувати свої творчі та фізичні сили на користь оточуючим людям, а негативний соціально-психологічний клімат призводить до емоційної пригніченості і виснаженості, як наслідок – стресового стану і низького рівня професійної діяльності, можливого виникнення конфліктних ситуацій.
Визначено роль управлінських рішень керівника у формуванні та підтримці позитивного соціально-психологічного клімату в педагогічному колективі дошкільного навчального закладу як діяльність, що спрямована на досягнення найефективнішого використання роботи працівників для досягнення цілей закладу. Основне завдання керівника дошкільного закладу – загальне керівництво процесом функціонування та розвитку системи управління та налагодження комфортного соціально-психологічного клімату в колективі, який прийнято вважати основою стабільного стану всього педагогічного колективу під час спільної діяльності по досягненню освітньої мети.
Відібрано найбільш ефективні способи формування та підтримки соціально-психологічного клімату в педагогічному колективі дошкільного навчального закладу: міжособистісні взаємодії та колективні взаємодії.
Avaliação do ciclo de vida da construção civil habitacional brasileira
Authors: Farias Emmanuel Eduardo Vitorino de , Oliveira Rui de , Silva Mônica Maria Pereira da , Melo Thiago Aguiar de 
Published: January 2022

A construção civil habitacional demanda grande quantidade de recursos naturais, gerando danos significativos ao meio ambiente. O presente trabalho tem como objetivo quantificar os impactos ambientais potenciais negativos dos insumos mais relevantes usados na construção de edificações residenciais por m² de área construída. Para representar as construções mais usuais no Brasil, foram utilizados como referência para os cálculos de insumos, três projetos residenciais padrão popular, empregados em programas habitacionais governamentais, com número de pavimentos e métodos construtivos distintos. Os impactos ambientais potenciais negativos foram estimados utilizando a metodologia Avaliação do Ciclo de Vida. Os resultados demonstram que os maiores impactos ambientais negativos, estão relacionados às edificações com mais de um pavimento, sobretudo em função do uso do cimento Portland e do revestimento cerâmico. Por fim, o presente estudo, fornece informações que auxiliam a tomada de decisão, na elaboração de projetos de arquitetura, nos processos construtivos e na aquisição de materiais de construção, visando minimizar os impactos ambientais potenciais negativos.
Preparo e administração de medicamentos de alta vigilância na perspectiva da segurança do paciente
Authors: Bastos Wylma Danuzza Guimarães , Leal Priscila Santos , Rodrigues Jamilly Fernanda Brito , Melo Dayzyane Farias dos Santos , Randau Karina Perrelli 
Published: January 2022

O preparo e administração de medicamentos são etapas no sistema de medicação, sendo a última parte do processo que antecede ao paciente. Um sistema composto por várias entradas e processos e com a participação dos profissionais do nível médio e superior, médicos, enfermeiros, farmacêuticos e técnicos em farmácia e enfermagem. Dentre a responsabilidade medicamentosa, existe um grupo denominado de Medicamentos de Alta Vigilância (MAV) ou Medicamentos Potencialmente Perigosos (MPP), que através da farmacovigilância exigem cuidados mais rigorosos, devido a sua composição e a capacidade de morte que possui, quando administrados de forma errônea. Portanto, esse trabalho tem como objetivo demonstrar a importância do preparo e administração dos MAV/MPP e sua interface com a segurança do paciente. Foi realizada uma revisão narrativa, a partir da pesquisa nas bases de dados eletrônicas Literatura Latino-Americana em Ciências da Saúde (LILACS), BIREME e Scientific Electronic Library Online (SciELO), com o recorte temporal de 2010 a 2021. Após aplicação dos critérios de inclusão e exclusão, e leitura completa dos textos, foram selecionados 10 trabalhos. O levantamento demonstrou a repetição dos erros com MAV envolvendo os medicamentos: heparina, fentanil, midazolam, nalbufina, pancurônio, dopamina, cloreto de potássio, tramadol, epinefrina, petidina, morfina e também com anestésicos e eletrólitos. A pesquisa concluiu sobre a fragilidade dos dados registrados nos artigos encontrados, não categorizando riscos em populações maiores, sendo incipientes e inexpressivos para uma realidade da abrangência do país e/ou por regionalidade.
Accuracy of Acceleration Time of Distal Arteries to Diagnose Severe Peripheral Arterial Disease
Authors: Trihan Jean-Eudes , Mahé Guillaume , Croquette Magali , Coutant Vicky , Thollot Cécile , Guillaumat Jérôme , Lanéelle Damien 
Published: January 2022

ContextAnkle-brachial index (ABI) and toe-brachial index (TBI) are the recommended tests for the diagnosis of lower extremity peripheral artery disease (PAD) and the assessment of its severity, whereas Doppler ultrasound (DUS) is usually used to localize vascular lesions. However, the performance of DUS as an alternative to TBI and ABI measurement is unknown.ObjectiveThe goals were (i) to evaluate the correlation between DUS parameters of distal arteries of the lower extremities with TBI in patients with PAD; (ii) to evaluate the correlation between DUS parameters of distal arteries with ABI; and (iii) to assess the diagnostic accuracy of maximal acceleration time of pedal arteries to detect toe pressure ≤30 mmHg.MethodsAn observational retrospective study was conducted for 1 year on patients with the diagnosis of PAD on DUS. Demographic data, ABI, TBI, and DUS parameters of the dorsal pedis and lateral plantar arteries (DPA and LPA) were recorded.ResultsSeventy-seven patients with 88 limbs were included, aged 69 [interquartile range: 11 years] with 28.6% of diabetic patients. The highest acceleration time of either DPA or LPA (ATmax) was the most correlated to TBI on both univariate (r = −0.78, p &lt; 0.0001) and multivariate analysis (p &lt; 0.0001). DUS parameters had a weaker correlation with ABI. ATmax &gt; 215 ms showed high diagnosis accuracy to a toe pressure of 30 mmHg or less [sensitivity of 86% [0.57–0.98] and negative predictive value of 97% [0.89–1.00]].ConclusionATmax demonstrates a high correlation with TBI in patients with PAD, and high diagnostic accuracy for detection of critical limb ischemia. Based on these results, ATmax can represent the next step in evaluating PAD severity with DUS, in patients with advanced lower extremity PAD.
Andrographolide Promotes Interaction Between Endothelin-Dependent EDNRA/EDNRB and Myocardin-SRF to Regulate Pathological Vascular Remodeling
Authors: Hu Wangming , Wu Xiao , Jin Zhong , Wang Zheng , Guo Qiru , Chen Zixian , Zhu Song , Zhang Haidi , Huo Jian , Zhang Lingling , Zhou Xin , Yang Lan , Xu Huan , Shi Liangqing , Wang Yong 
Published: January 2022

IntroductionPathological vascular remodeling is a hallmark of various vascular diseases. Smooth muscle cell (SMC) phenotypic switching plays a pivotal role during pathological vascular remodeling. The mechanism of how to regulate SMC phenotypic switching still needs to be defined. This study aims to investigate the effect of Andrographolide, a key principle isolated from Andrographis paniculate, on pathological vascular remodeling and its underlying mechanism.MethodsA C57/BL6 mouse left carotid artery complete ligation model and rat SMCs were used to determine whether Andrographolide is critical in regulating SMC phenotypic switching. Quantitative real-time PCR, a CCK8 cell proliferation assay, BRDU incorporation assay, Boyden chamber migration assay, and spheroid sprouting assay were performed to evaluate whether Andrographolide suppresses SMC proliferation and migration. Immunohistochemistry staining, immunofluorescence staining, and protein co-immunoprecipitation were used to observe the interaction between EDNRA, EDNRB, and Myocardin-SRF.ResultsAndrographolide inhibits neointimal hyperplasia in the left carotid artery complete ligation model. Andrographolide regulates SMC phenotypic switching characterized by suppressing proliferation and migration. Andrographolide activates the endothelin signaling pathway exhibited by dramatically inducing EDNRA and EDNRB expression. The interaction between EDNRA/EDNRB and Myocardin-SRF resulted in promoting SMC differentiation marker gene expression.ConclusionAndrographolide plays a critical role in regulating pathological vascular remodeling.
Inflammasome Targeted Therapy as Novel Treatment Option for Aortic Aneurysms and Dissections: A Systematic Review of the Preclinical Evidence
Authors: Wortmann Markus , Klotz Rosa , Kalkum Eva , Dihlmann Susanne , Böckler Dittmar , Peters Andreas S. 
Published: January 2022

Both aortic aneurysm and dissection are life threatening pathologies. In the lack of a conservative medical treatment, the only therapy consists of modifying cardiovascular risk factors and either surgical or endovascular treatment. Like many other cardiovascular diseases, in particular atherosclerosis, aortic aneurysm and dissection have a strong inflammatory phenotype. Inflammasomes are part of the innate immune system. Upon stimulation they form multi protein complexes resulting mainly in activation of interleukin-1β and other cytokines. Considering the gathering evidence, that inflammasomes are decisively involved in the emergence and progression of aortic diseases, inflammasome targeted therapy provides a promising new treatment approach. A systematic review following the PRISMA guidelines on the current preclinical data regarding the potential role of inflammasome targeted drug therapy as novel treatment option for aortic aneurysms and dissections was performed. Included were all rodent models of aortic disease (aortic aneurysm and dissection) evaluating a drug therapy with direct or indirect inhibition of inflammasomes and a suitable control group with the use of the same aortic model without the inflammasome targeted therapy. Primary and secondary outcomes were incidence of aortic disease, aortic rupture, aortic related death, and the maximum aortic diameter. The literature search of MEDLINE (via PubMed), the Web of Science, EMBASE and the Cochrane Central Registry of Registered Trials (CENTRAL) resulted in 8,137 hits. Of these, four studies met the inclusion criteria and were therefore eligible for data analysis. In all of them, targeting of the NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome effectively reduced the incidence of aortic disease and aortic rupture, and additionally reduced destruction of the aortic wall. Treatment strategies aiming at other inflammasomes could not be identified. In conclusion, inflammasome targeted therapies, more precisely targeting the NLRP3 inflammasome, have shown promising results in rodent models and deserve further investigation in preclinical research to potentially translate them into clinical research for the treatment of human patients with aortic disease. Regarding other inflammasomes, more preclinical research is needed to investigate their role in the pathophysiology of aortic disease.Protocol Registration: PROSPERO 2021 CRD42021279893, https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021279893
Baseline Corrected QT Interval Dispersion Is Useful to Predict Effectiveness of Metoprolol on Pediatric Postural Tachycardia Syndrome
Authors: Wang Yuanyuan , Sun Yan , Zhang Qingyou , Zhang Chunyu , Liu Ping , Wang Yuli , Tang Chaoshu , Jin Hongfang , Du Junbao 
Published: January 2022

ObjectivesThe study was designed to explore the role of baseline-corrected QT interval dispersion (QTcd) in predicting the effectiveness of metoprolol on pediatric postural tachycardia syndrome (POTS).MethodsThere were two groups in the study, the discovery group and the validation group. The children with POTS in the discovery group were treated with oral metoprolol, with the completed necessary medical records, head-up tilt test (HUTT), blood chemistry, and 12-lead ECG before treatment at the pediatrics of Peking University First Hospital, China. According to whether the symptom score (SS) was reduced by more than 2 points after administration with oral metoprolol as compared with that before treatment, the children with POTS were separated into responders and non-responders. The demographic characteristics, hemodynamic indicators, and the QTcd of the two groups were compared, and the estimate of the baseline QTcd in predicting the treatment response to metoprolol was tested through a receiver operating characteristic (ROC) analysis. Other 24 children suffering from POTS who were, administrated with metoprolol at the pediatrics of Peking University First Hospital were included in the validation group. The sensitivity, specificity, and accuracy of the baseline QTcd in the prediction of the effectiveness of metoprolol on POTS were validated in children.ResultsThe pre-treatment baseline QTcd in responders treated with metoprolol was longer than that of the non-responders in the discovery group [(66.3 ± 20.3) ms vs. (45.7 ± 19.9) ms, p = 0.001]. The baseline QTcd was negatively correlated with SS after metoprolol treatment (r = −0.406, p = 0.003). The cut-off value of baseline QTcd for the prediction of the effectiveness of metoprolol on pediatric POTS was 47.9 ms, yielding a sensitivity of 78.9% and a specificity of 83.3%, respectively. The validation group showed that the sensitivity, specificity, and accuracy of the baseline QTcd ≥ 47.9 ms before treatment for estimating the effectiveness of metoprolol on POTS in children were 73.7, 80.0, and 75.0%, respectively.ConclusionBaseline QTcd is effective for predicting the effectiveness of metoprolol on pediatric POTS.
Predicting the Risk of Psoriatic Arthritis in Plaque Psoriasis Patients: Development and Assessment of a New Predictive Nomogram
Authors: Liu Panpan , Kuang Yehong , Ye Li , Peng Cong , Chen Wangqing , Shen Minxue , Zhang Mi , Zhu Wu , Lv Chengzhi , Chen Xiang 
Published: January 2022

ObjectiveThis study aimed to develop a risk of psoriatic arthritis (PsA) predictive model for plaque psoriasis patients based on the available features.MethodsPatients with plaque psoriasis or PsA were recruited. The characteristics, skin lesions, and nail clinical manifestations of the patients have been collected. The least absolute shrinkage was used to optimize feature selection, and logistic regression analysis was applied to further select features and build a PsA risk predictive model. Calibration, discrimination, and clinical utility of the prediction model were evaluated by using the calibration plot, C-index, the area under the curve (AUC), and decision curve analysis. Internal validation was performed using bootstrapping validation. The model was subjected to external validation with two separate cohorts.ResultsAge at onset, duration, nail involvement, erythematous lunula, onychorrhexis, oil drop, and subungual hyperkeratosis were presented as predictors to perform the prediction nomogram. The predictive model showed good calibration and discrimination (C-index: 0.759; 95% CI: 0.707–0.811). The AUC of this prediction model was 0.7578092. Excellent performances of the C-index were reached in the internal validation and external cohort validation (0.741, 0.844, and 0.845). The decision curve indicated good effect of the PsA nomogram in guiding clinical practice.ConclusionThis novel PsA nomogram could assess the risk of PsA in plaque psoriasis patients with good efficiency.