bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pilot study of new statistical models for prognostic factors in short term survival of oral cancer
Authors: Oluwatobi Awodutire Phillip , Ruth Ilori Oluwatosin , Uwandu Chigozie , Adeniyi Akadiri Oladimeji 
Published: August 2022

Background: Survival times of oral cancer are poorly documented in Nigeria. This is partly due to poor documentation and limited investigations to elicit sufficient prognostic factors. In this study, we applied a new statistical model for survival times of oral cancer patients considering limited prognostic factors.
Methods: A total of 29 cases of Oral cancer patients with stage I to IV invasive primary oral cancer treated at the University of Port Harcourt, Nigeria between 2008 and 2015 were used to generate prognostic models. Profiled prognostic factors include age, stage of tumor development, habitus, and treatment modalities. The baseline statistical distributions considered were Exponential, Weibull, Lognormal and Log-logistic distributions. The Chi-Square test was considered for the suitability of the model chosen. A comparison of the model performance was done using the Akaike Information Criterion (AIC).
Results: Seventeen (58.6%) of the oral cancer patients were males and 12(41.4%) were females within the age range of 19 and 73 years. Sixteen (55.2%) of the patients were censored while 13(44.8%) were not censored. The estimated median survival time (MST) for the males was 29.50 months while that of the female was 7 months. Four parametric statistical models were tested and all identified tumor stage [cTNM stage (p= 0.000)] and treatment modality (p= 0.000) as more important predictors of survival. The models were then compared, using the Akaike Information Criterion (AIC) to determine the model best fit for the data. Themodel with the lowest AIC and so considered the best was the Weibull Statistical Model (WSM) with AIC= 100.76.
Conclusions: This study suggests that the Weibull survival model is the best fit for estimating oral cancer survival times especially where only limited prognostic factors are available. Larger studies are required to validate the findings of this pilot.
Keywords: New statistical; short term survival; oral cancer.
Association between hair dye use and cancer in women: a systematic review and meta-analysis of case-control studies
Authors: Ahmadi Mohadeseh , Saeedi Majid , Hedayatizadeh-Orman Akbar , Eslami Mahboobeh , Janbabai Ghasem , Alizadeh-Navaei Reza 
Published: August 2022

Background: The use of hair dye for cosmetic purposes appears to be increasing worldwide. As 50-80% of women use hair dye throughout their lifetimes, the possible association between hair dye use and cancer is a public health concern.
Method: This systematic review was performed by retrieving studies from PubMed, Scopus, WOS, and ProQuest databases. The inclusion criteria were case-control studies evaluating the association between hair dye use and cancer in women. Women with cancer who have used any hair dye were the focus of our study.
Results: The present study combined 28 studies, to assess the association between hair dye use and cancer. The pooled odds ratio (OR) of hematopoietic system cancers among those who have generally ever used any type of hair dyes was 1.10 (95% CI:1.01-1.20) in 17 studies. In 11 studies investigating hair dye made before and after 1980 as a risk factor for cancer, the pooled OR for cancer was 1.31(95% CI:1.08-1.59). Likewise, in the 13 studies that evaluated the association of light and dark hair dye with cancer, the risk among those using dark hair dye increased by 9%, compared to non-users (OR=1.09; 95% CI:0.95-1.25).
Conclusion: The present study suggests that, although the use of hair dye may increase the risk of cancer among users, a more detailed evaluation is required to assess the type of hair dye use in terms of guidelines and metrics.
Keywords: Hair dye; cancer; meta-analysis.
Quantifying the relationship of HIV infection with clinicopathological spectrum and outcome among patients with colorectal cancer in a South African population
Authors: SK Pillay , Z Moolla , Y Moodley , TE Madiba 
Published: August 2022

Introduction: Literature is limited on HIV and colorectal cancer (CRC) in sub-Saharan Africa despite it being the epicentre of the HIV epidemic.
Purpose: To compare clinicopathological features and outcome of CRC in HIV-negative and HIV-positive patients.
Methods: Retrospective analysis of a prospective CRC database. Demographic details, HIV status, anatomical site, disease stage, treatment and follow-up were documented.
Results: Of 715 patients with CRC, 145 and 570 tested positive and negative respectively for HIV. Median age was 45 (IQR 36-53 and 57 (IQR 45-66) years among HIV-positive and HIV-negative patients respectively (p<0.0001). Tumour differentiation differed between the two groups (p=0.003) but staging was not different (p=0.6). Surgical resection rate was 52% for HIV-positive patients versus 59% for HIV-negative patients (p=0.07). Median follow-up was 9 (IQR 2-20.5) months for HIV-positive patients and 12 (IQR 6-29) months for HIV-negative patients (p=0.154). Recurrence rate was 14.7% among HIV positive patients and 6.8% in HIV negative patients (p=0.089).
Conclusion: When compared with HIV-negative patients, HIV-positive patients with CRC presented at a younger age and tended to have lower surgical resection rates. There was no difference between the two groups with CRC in terms of anatomical sub-site distribution, disease staging and recurrence rates.
Keywords: Colorectal cancer; colon cancer; rectal cancer; HIV; Outcome.
Effect of low-dose lanthanum carbonate on calcium and phosphorus metabolism in Asian Patients with end-stage renal disease, maintenance hemodialysis and hyperphosphatemia
Authors: Cui Xiaofei , Jiang Shuning , Liu Liang , Tang Xuejie , Chen Yan 
Published: August 2022

Objective: This study aimed to examine whether a 12-week small-dose lanthanum carbonate (LaCO3; 500 mg/d) treatment could improve calcium and phosphorus metabolism and parathyroid function in Asian patients with end-stage renal disease (ESRD) under hemodialysis.
Methods: This was a prospective observational study of patients treated at our Hospital between 10/2014 and 02/2015. The patients were given 500 mg/d of LaCO3 with lunch for 12 weeks.
Results: Baseline and after 12-week treatment serum phosphorus levels were 2.49±0.51 mmol/L and 1.65±0.34 mmol/L (P<0.001). The baseline and after 12-week treatment calcium×phosphorus product were 69.40±17.34 mg2/dL2 and 44.27±9.67 mg2/dL2 (P<0.001). There was no significant difference in serum calcium and iPTH levels from baseline to after 12 weeks treatment (both P>0.05). Fourteen (25.9%) patients developed gastrointestinal adverse reactions to LaCO3and 10 patients improved after treatment.
Conclusion: Far below the 1.5-3.0g/d required by the drug instructions, LaCO3 500 mg/d for 12 weeks can still reduce serum phosphorus level and calcium × phosphorus product, without serum calcium and iPTH levels increase.
Keywords: Low dose; Lanthanum carbonate; Hyperphosphatemia; End-stage renal disease; Hemodialysis; Asian.
Weight distribution asymmetry in relation to walking speed in children with spastic cerebral palsy
Authors: M Ibrahim Nahla , Elsayed Abbass Mai 
Published: August 2022

Background: Gait speed and postural stability are indicators of community level ambulation and may be a valuable measure of disability.
Objectives: to investigate the relation between the distribution of weight on both lower extremities and gait speed in children with spastic cerebral palsy.
Methods: Evaluation for weight distribution on both lower limbs and speed during gait for sixty children with spastic diplegia and forty-five children with hemiplegia was carried out by the Biodex gait trainer. Pearson correlation test was conducted to determine the relation of the symmetry index and the percent of weight bearing to speed.
Results: A significant weak positive correlation was found between speed and symmetry index in diplegic group, while there was a non-significant weak negative correlation between speed and symmetry index was noticed in hemiplegic group. Nonsignificant weak positive correlation between speed and weight on most affected side was recorded in diplegic group. While in hemiplegic group, there was significant weak negative correlation between weight on affected side and speed.
Conclusion: Children with cerebral palsy demonstrate asymmetrical weight distribution during walking. Physical therapy training should be directed to enhance weight bearing distribution thus improving gait and postural stability.
Keywords: Physical Therapy Modalities; Pediatrics; Rehabilitation.
Towards developing a comprehensive treatment schedule for patients with cerebral palsy: factors influencing patient’s adherence to physiotherapy treatment
Authors: Uchenwoke Ikenna Chigozie , Ofodum Mirian Chidimma , Nwachukwu Paul Chinonso , Osuoha Onyekachi Christiana , Okonkwo Kingsley Kenechukwu , Anih Chidera Lynda 
Published: August 2022

Purpose: This study is aimed to identify factors influencing patient’s adherence to treatment in a bid to characterize the extent to which these factors are considered while developing a treatment schedule for patients with cerebral palsy in Nigeria
Methods: Descriptive cross-sectional study of physiotherapists involved in the care of patients with cerebral palsy. Factors influencing treatment adherence were assessed using a pre-tested, self-administered questionnaire. Participants were sampled from physiotherapists working at University of Nigeria Teaching Hospital, Enugu State, Nigeria. The data were analyzed using descriptive statistics of percentage and frequencies.
Results: A total of fifty three (31 males and 22 females) physiotherapists completed and returned the questionnaire. Participants (84.9%) agreed that patients occasionally forget to meet up with their appointment days; with majority of them agreeing that distance to the clinic and economic factor (cost of treatment and transportation) influence patient’s adherence to treatment. Presence/absence of a caregiver and relationship between patients and their physiotherapist are also important factors influencing patient’s treatment schedules.
Conclusion: Distance to the clinic when compared to other (economic, patient-therapist relationship) factors is the major barrier to patient’s adherence to treatment and therefore should be considered while developing treatment schedules for patients with cerebral palsy.
Keyword: Cerebral palsy; Treatment schedule; Adherence; Physiotherapy; Nigeria.
Perceived barriers and facilitators to antiretroviral therapy adherence among youth aged 15-24 years at a regional HIV clinic in South-Western Uganda: a qualitative study
Authors: Jjumba Isaac , Kanyesigye Micheal , Ndagijimana Gerald , Wattira James , Olong Clinton , Akumu Olok Rose , Beebwa Esther , Muzoora Conrad 
Published: August 2022

Introduction: South-Western region has the second highest HIV prevalence in Uganda. Youth aged 15-24 have shown poor adherence to antiretroviral therapy compared to the older cohorts. Previous studies from other regions have shown various barriers and facilitators. Our study was designed to describe specific barriers and facilitators to treatment adherence among youths in a large regional HIV clinic in southwestern Uganda.
Methods: We used a phenomenological qualitative study design conducted amongst 30 purposively selected HIV positive youth aged 15-24 years enrolled at Mbarara Regional Referral Hospital HIV clinic on ART for a period of at least one year and 6 key informants using in-depth interviews. The data was collected in an inductive manner during the period between 21st July and 17th August 2020. The recordings were backed up, transcribed verbatim and then analyzed manually using thematic content analysis.
Results: The barriers to ART adherence were described in three descending categories as perceived treatment burden, perceived resultant stigma and discrimination, whereas the main facilitators were; perceived usefulness of HIV medications, availability of free services and Social support.
Conclusion: Youths aged 15-24 have challenges with ART associated treatment burden and fear to disclose their HIV status because of the resultant stigma from their communities. Many have however accepted the fact that HIV medications are lifesaving and are strongly motivated to adhere to their medications despite the circumstances.
Keywords: Barriers; Facilitators; Adherence; HIV/AIDS; Young Adults.
Renal cyst mimicking hydronephrosis after uterine artery ligation for postpartum haemorrhage
Authors: Chibuoke Ngene Nnabuike 
Published: August 2022

Background: The proximity of the uterus and the cervix to the urinary tract predisposes the latter to injury during obstetrical and gynaecological surgical procedures. Following a difficult surgical procedure on the lower uterine segment and or adnexa, urinary tract injury should be excluded.
Methods: A booked 39-year-old G3P2 lady who suffered an ischaemic stroke in the index pregnancy had a caesarean delivery at 39 weeks of gestation and sustained an extensive tear that extended inferiorly on the left lateral aspect of the uterus and this resulted in postpartum haemorrhage. Following the repair of the tear, uterine artery ligation was performed to achieve haemostasis.
Results: Postoperatively, conventional ultrasonography which was performed to exclude ureteric injury suggested left hydronephrosis and a preliminary report of computerized tomography (CT) showed the same finding. The patient subsequently had left ureteric stenting. The final report of the CT scan was delayed but showed a simple left renal cyst and no hydronephrosis.
Conclusion: Renal cyst is a differential diagnosis of hydronephrosis. Delayed availability of the final result of medical investigations jeopardises patients’ safety. A preliminary imaging report is prone to error and its use to determine the indication for an invasive procedure should be limited to emergencies.
Keywords: Uterine artery ligation; preliminary imaging report; ureteric injury.
Prevalence of venous thromboembolism risk factors in hospitalized patients at the University of Nigeria Teaching Hospital, Enugu Nigeria
Authors: Doris Ezigbo Eyiuche , Ukamaka Nwagha Theresa , Chinedu Nwuzor Victor 
Published: August 2022

Background: Venous thromboembolism (VTE) is a common and lethal disease. Assessing the risk factors will help to modify exposures.
Aim: This study, assessed VTE risk factors in hospitalized patients at the University of Nigeria Teaching Hospital, Enugu.
Patients and Methods: This was an observational, case-control study. Three hundred and fifty (350) patients were recruited for the study: This comprised 150 medical patients, 140 surgical patients and a population of 60 healthy control group. Subjects were evaluated once using the Caprini risk assessment model (RAM).
Results: Over 50% of all hospitalized patients, were at risk for VTE. Surgical patients were at a higher risk than medical patients. Hemoglobin concentration was associated with the risk of VTE in surgical patients, while d-dimer was associated with VTE risk in medical patients.
Conclusion: This study shows a high prevalence of VTE risk factors among hospitalized patients at the University of Nigeria Teaching Hospital.
Keywords: Venous Thromboembolism; Risk factors; D-dimer; Patients; Nigeria.
Job Satisfaction and Psychological Health of Staff in a Nigerian University
Authors: Efegoma Y.C. , Ofili A.N. , Isah E.C. 
Published: August 2022

Background: Job satisfaction is the extent to which people like their jobs and the positive perception towards work. Work experiences have significant influence on psychological health. This study assessed job satisfaction and psychological health of university staff in a Nigerian university.
Methods: Four hundred and sixty-one respondents selected by a two-stage cluster sampling technique participated in this descriptive cross- sectional study. Psychological health was assessed using the General Health Questionnaire 12 (GHQ 12). Data was analyzed using SPSS (26.0). Level of significance set at p ≤ 0.05 and results presented using of tables and graphs.
Results: The mean age of the respondents was 36.02 ± 9.12 years, 261 (56.6%) were males, 311 (67.5%) married, all were literate and 380 (82.4%) had been in employment for up to 10 years, (mean duration of employment = 8.3 ± 6.92 years). Overall, 316 (68.5%) of staff were satisfied with their jobs and 342 (74.2%) were in psychologically stable health. Self-reported factors like job security, relationships with co-workers and supervisors impacted positively on job satisfaction while others like amount of paid vacation and promotion opportunity did not. Psychological disorder occurred more significantly among staff dissatisfied with their jobs p<0.001.
Conclusion: A majority of staff were satisfied with their jobs and were in psychologically stable health. There is need to address factors impacting negatively on job satisfaction to further improve psychological health of university staff.
Maternal and Neonatal Outcomes of Booked and Un-booked Pregnancies in Benin City, Southern Nigeria: A Comparative Study
Authors: Okojie O.H. , Ogboghodo E.O. , Omoijuanfo E.A. 
Published: August 2022

Background: Nigeria contributes more obstetric, postpartum, and neonatal deaths and stillbirths than any other country globally. Booking and receiving antenatal care (ANC) is a vehicle for multiple interventions and programmes which improve maternal and neonatal outcomes. This study was conducted to assess and compare the maternal and neonatal outcomes of booked and un-booked pregnancies in Benin City, Southern Nigeria.
Methods: A comparative cross-sectional total population study was carried out among booked and un-booked in-patients who had delivered either in a secondary or a tertiary health facility in Benin City. Data was collected using an intervieweradministered questionnaire and patients case notes. Maternal and neonatal outcomes were assessed as favourable and unfavourable and compared with booking status. A p-value <0.05 was considered statistically significant.
Results: A total of 390 (260 booked and 130 un-booked) women, with a mean age (SD) of 30.86 ± 5.77 years (booked) and 28.48 ± 6.22 years (un- booked), participated in the study. A higher proportion, 56 (43.1%) of un-booked women had obstetric complications compared to booked women, 85 (32.7%) (p = 0.044). Fetal morbidity was 9 (3.5%) in booked mothers, compared to 21 (16.2%) of un-booked mothers. (p < 0.001).
Conclusion: Maternal and neonatal outcomes were better in booked pregnancies. Stakeholders should ensure provision of health and hospital policies aimed at improving ANC to prevent poor maternal and neonatal outcomes.
Bimbingan Belajar Sebagai Upaya untuk Menghindari Learning Loss di Desa Aji Kagungan Kecamatan Abung Kunang, Kotabumi Lampung Utara
Authors: Wulan Dari  , Juwita Arni , Widia Sari Kiki , Anggraini Jayanti Sely , Widayati Sri 
Published: August 2022

Pandemi Covid-19 menjadi momok bagi masyarakat. Indonesia menjadi salah satu negara yang merasakan dampaknya. Segala bentuk kegiatan tidak luput dari pembatasan bahkan penghentian. Kegiatan pembelajaran di sekolah pun terpaksa dibatasi dan belajar secara daring (dalam jaringan), begitu pun yang terjadi di Desa Aji Kagungan. Dikhawatirkan jika terus berlanjut maka akan terjadi learning loss. Beberapa anak mengalami kendala dalam melaksanakan pembelajaran secara online. Oleh sebab itu, mahasiswa KKN Universitas Muhammadiyah Kotabumi mengadakan program bimbingan belajar bahasa Inggris dan bimbingan membaca dan menulis dengan menggunakan metode ceramah, diskusi, dan pendampingan. Pembelajaran dibuat semenarik mungkin agar siswa belajar dengan cara yang menyenangkan. Hasil dari kegiatan KKN di Desa Aji Kagungan, Kecamatan Abung Kunang Kotabumi Lampung Utara, yaitu siswa terbantu dengan pemahaman tugas-tugas sekolah, terbantu dengan belajar membaca dan menulis. Selain itu, bagi siswa yang tidak mendapatkan mata pelajaran bahasa Inggris di sekolahnya mengetahui dasar-dasar bahasa Inggris dari mahasiswa KKN.

Kata Kunci: Pendampingan, Bimbingan Belajar, Learning Loss
Afiksasi Pembentukan Verba dalam Majalah Tempo "Darurat Covid-19" Edisi 23 - 29 Maret 2020 Sebagai Alternatif Bahan Ajar di Sekolah Menengah Atas.
Authors: Nur Hasanah Isnaini , Widayati Sri , Ratnaningsih Dewi 
Published: August 2022

Abstrak: Masalah dalam penelitian ini adalah afiksasi pembentukan verba dalam majalah Tempo “Darurat Covid-19” Edisi 23—29 Maret 2020 sebagai alternatif bahan ajar di sekolah menengah atas. Tujuan penelitian ini untuk mengetahui afiksasi pembentukan verba dalam majalah Tempo “Darurat Covid-19” Edisi 23—29 Maret 2020. Metode yang digunakan adalah deskriptif kualitatif. Hasil dari penelitian ini ditemukan 168 data yang berupa afiksasi pembentukan verba berprefiks me-, ber-, di-, dan ter-. Dari aspek bahan ajar, majalah Tempo “Darurat Covid-19” Edisi 23—29 Maret 2020 telah memenuhi kriteria yang baik sehingga layak dijadikan sebagai alternatif bahan ajar bagi peserta didik di sekolah menengah atas.
ALIH KODE DAN CAMPUR KODE PADA NOVEL LENTERA AISHA KARYA ARY YULISTIANA SEBAGAI ALTERNATIF BAHAN AJAR DI SEKOLAH MENENGAH ATAS
Authors: Artica Malau Reka Octaviani 
Published: August 2022

Masalah dalam penelitian ini ialah alih kode dan campur kode pada novel Lentera Aisha karya Ary Yulistiana sebagai alternatif bahan ajar di sekolah menengah atas. Tujuan penelitian ini yaitu untuk mendeskripsikan alih kode dan campur kode pada novel Lentera Aisha karya Ary Yulistiana sebagai alternatif bahan ajar di sekolah menengah atas. Metode yang digunakan deskriptif kualitatif. Dari hasil penelitian ditemukan tiga puluh dua kutipan yang keseluruhannya terdiri dari tujuh belas campur kode ke luar, tujuh campur kode ke dalam dan delapan campur kode campuran.Data alih kode intern dan ekstern tidak ditemukan. Novel Lentera Aisha karya Ary Yulistiana dapat dijadikan sebagai alternatif bahan ajar di sekolah menengah ataskarena ditinjau dari aspek kebahasaan, psikologi, dan latar belakang sosial budaya siswa telah memenuhi kriteria bahan ajar
Pengaruh Pemasaran Internal dan Kepuasan Kerja Terhadap Kinerja RSI Ibnu Sina Yarsi Sumbar Menurut Persepsi Karyawan Tahun 2020
Authors: Herman Meri Herliza , Yeni Yulia Hendri 
Published: August 2022

Latar Belakang: Pemasaran internal di rumah sakit berperan penting dalam menjelaskan persepsi karyawan terhadap kinerja organisasi dan kualitas layanan.Tujuan penelitian ini adalah untuk menganalisis pengaruh pemasaran internal dan kepuasan karyawan terhadap kinerja Rumah Sakit Islam Ibnu Sina.
Metode: Penelitian ini merupakan penelitian deskriptif kuantitatif dengan teknik pengumpulan data berupa penyebaran kuesioner kepada subjek penelitian. Setelah dilakukan pengumpulan data kemudian data diolah dengan menggunakan Sem smartPls3.0, dan menginterpretasikan hasil analisis tersebut, sehingga dapat diambil kesimpulan yang diperlukan dalam menjawab rumusan masalah.
Hasil: Pemasaran internal dan kepuasan kerja berpengaruh signifikan terhadap kinerja organisasi.
Kesimpulan: Pemasaran internal telah diterapkan dengan cukup baik di RSI Ibnu dan terdapat pengaruh pemasaran internal terhadap kinerja organisasi melalui kepuasan kerja karyawan sebagai variable intervening.

Kata Kunci : Pemasaran Internal, Karyawan, Kepuasan, Kinerja