bluuebunny/crossref_metadata_2025_split huggingface dataset:
Benthic macroinvertebrates in a protected area within the Brazilian savannah: environmental factors negatively affect diversity
Authors: Silva Márcia Cristina Martins da , Cezário Rodrigo Roucourt , Pivello Vânia Regina , Matos Dalva Maria Silva 
Published: September 2022

Abstract
In the Neotropics, especially in southeastern Brazil, due to sugarcane and eucalypt monocultures, and the expansion of industries and the largely unplanned urban centers entire aquatic ecosystems are threatened. Nonetheless, benthic macroinvertebrates are important biomonitoring tools to assess the biotic and abiotic condition of endangered freshwater environments. In this study we address how benthic macroinvertebrate diversity respond to the combined effect of local environmental factors. We also aimed to evaluate how benthic macroinvertebrates diversity respond according to the habitat integrity. We expected to find higher diversity in the sampling sites with higher habitat integrity (i.e., low potential of hydrogen, electrical conductivity and water temperature, and high canopy coverage and concentration of dissolved oxygen). By using a multivariate approach (i.e., PCA) and a regression analysis (i.e., Linear Mixed-Effect Model) we were able to address the combined effect of local environmental variables on the benthic macroinvertebrate community. Our results show a negative effect of the environmental factors on the benthic macroinvertebrate diversity. As expected, sites with higher integrity and water quality values according to, respectively, the Habitat Integrity Index (i.e., HII) and the Biological Monitoring Working Party (i.e., BMWP’) tended to have higher benthic macroinvertebrates diversity. This is the first report that provides knowledge of the benthic macroinvertebrate community in the Paulicéia river, within the Cerrado Pé-de-Gigante, a conservation unity of full protection of a State Park in the Neotropics.
Analgesic efficacy of Transverse thoracic muscle plane block (modified approach) in off-pump coronary artery bypass grafting : A retrospective cohort study
Authors: ZHANG Xiao-yan , ZHANG Yu , SUN Ying-jie , FAN Hong-na , DIAO Yu-gang 
Published: September 2022

Abstract
Background:To investigate the safety and effectiveness of bilateral transverse thoracic muscle plane (TTP) block (modified approach) combined with general anesthesia in off-pump coronary artery bypass grafting (OPCABG). Methods :The clinical data of 60 patients undergoing OPCABG, selected from March to August 2021 in general hospital of northern theater command, were retrospectively analyzed and divided into TTP block with general anesthesia group ( group T, n=30) and general anesthesia group (group G, n=30) according to anesthesia mode. Patients in group T undergone bilateral TTP block (modified approach, 0.25% ropivacaine 20 ml each side) before anesthesia induction, and both groups were induced by routine anesthesia. The mean arterial pressure (MAP) and heart rate (HR) were recorded and analyzed before and after cutting, splitting and closing the sternum, and the total dosage of sufentanil at the end of operation was recorded. The levels of lactic acid and blood glucose were detected with blood gas analysis before the operation , at the end of the operation, and at 2 h, 4 h, 6 h, 8 h, 10 h, 12 h, 16 h, 20 h and 24 h after the operation. The visual analogue scale (VAS) scores in resting and moving state were recorded at 12 h, 24 h and 48 h after operation. The numbers of patients who were first added analgesic drugs (pethidine) on the day, the first day and the second day after operations were recorded, and the occurrence of postoperative adverse reactions was recorded. Results: Compared with group G, the change rate of MAP and HR in group T decreased slightly at each time point, but the difference was not statistically significant (P>0.05). The levels of lactic acid at 2 h and 4 h after operation and the levels of blood glucose at 2 h, 4 h and 6 h after operation were significantly lower than those of group G (P<0.05). Compared with group G, the VAS scores (resting and moving state) of group T significantly decreased at 12 h (resting state) after operation (P<0.05). Compared with group G , the extubation time of group T was shorter, but with no statistical significance (P>0.05); while the dosage of sufentanil in group T was obviously decreased, and the number of patients who were added analgesics at the postoperative day was markedly reduced (P<0.05). The incidence of postoperative chills was obviously lower in group T than in group G (P<0.05). No significant difference existed between the two groups in the incidence of postoperative nausea and vomiting, arrhythmia, pruritus, abdominal distention and infection in operation area 3 days post operation (P>0.05). Conclusion: Bilateral TTP block (modified approach) combined with general anesthesia can provide good perioperative analgesia for patient undergoing OPCABG, reduce the use of opioids, and inhibit the stress response to a certain extent, thus having better safety and effectiveness.
The Prevalence of Musculoskeletal Pains among Healthcare Workers
Authors: Arianezhad Ali , Khorramizadeh Maryam , Kord Zaynab , Norouzi Ali , Zarasvand Behrooz 
Published: September 2022

Abstract
Background and Objectives: Musculoskeletal pains refer to damages people with inappropriate body positions may suffer in their jobs and are one of the most common occupational diseases.With hospital personnel and those working in this environment like physicians, nurses, interns and nursing apprentices falling into active occupational groups, this study sought to determine the prevalence of musculoskeletal pains in these occupations.Method: This descriptive-analytical cross sectional study was conducted in Dr. Ganjavian Hospital in Dezful in 2020 on 239 physicians, nurses, interns and nursing apprentices using a random sampling method. To assess musculoskeletal disorders in people, the Nordic Musculoskeletal Questionnaire (NMQ) was used. The data normalization was examined using chi-squared test and contingency tables. The whole analyses were done by SPSS 16.Results: Musculoskeletal pains in people with higher job and study-related activities were more prevalent than other people in the study. There was also a significant relationship among gender, median age, the frequency of exercise and BMI with the prevalence of musculoskeletal pains. A significant relationship was found between different occupational groups (physicians, nurses, interns and nursing apprentices) and the presence of pain in wrists, hands and elbows, too.Conclusions: Our results showed that the presence of musculoskeletal disorders was relatively high in the lumbar regions (51.7%) and necks (49.6%) and in general musculoskeletal disorders are significantly higher among physicians and nurses, a reason of which can be related to a higher median age in these groups than in apprentices. Thus, it seems necessary to both improve working conditions for hospital staff and raise their awareness of the risks leading to musculoskeletal disorders.
Bayesian probabilistic approaches for predicting the debris-flow sediment volume using limited site investigation data
Authors: Tian Mi , Xiong Zimin , Li Lihua , Sheng Xiaotao 
Published: September 2022

Abstract
Many empirical relationships have been proposed to relate the sediment volume to various influencing factors. However, the accuracy of such empirical relationships generally requires a large number of observation data, which is difficult to be guaranteed at a specific site. Moreover, based on the limited investigation data, a complicated empirical model with more input factors may be an overfitted equation. Therefore, how to develop a reliable prediction model of debris-flow sediment volume still remains a great challenge. This paper develops a robust method to establish the most appropriate model for predicting the debris-flow volume based on Bayesian inference. Firstly, the limited site investigation data are preprocessed by a series of multicollinearity analysis to select the candidate input variables. Then, a Bayesian framework is developed to select the most appropriate model among alternatives and identify its corresponding model parameters based on the site investigation data and prior knowledge. To address the multi-dimensional issues in Bayesian inference, a multi-chain method, specifically DREAM(ZS) algorithm, is used to obtain the posterior distribution of model parameters of a candidate model to overcome the inefficient sampling problems of single-chain Markov chain Monte Carlo (MCMC) methods (e.g., Metropolis-Hastings algorithm). MCMC samples of model parameters are subsequently applied to calculate the evidence of a candidate model using Gaussian copula, making the DREAM(ZS) algorithm feasible in model selection problem. Results show that compared with the pre-existing empirical relationship, the proposed approaches provide a simpler and more accurate model by reasonably considering the balance between data fitting and model uncertainty.
A tool-box strategy for layer-by-layer assembly of ultrathin hybrid films from graphene oxide and chromophores for organic electronics
Authors: Gusarova Elizaveta A. , Zvyagina Alexandra I. , Aleksandrov Alexey E. , Averin Alexey A. , Tameev Alexey R. , Kalinina Maria A. 
Published: September 2022

Abstract
A combinatorial interfacial assembly method was developed for fabrication functionally different 2D hybrids by using the same starting set of components comprising graphene oxide, perylene chromophore, polydiacetylene surfactant and nickel nitrate as a source of divalent ions. The components were assembled through either hydrogen or coordination bonding into layered nanofilms with a thickness 8-20 nm to integrate them into conventional ITO-based solar cells. Depending on their composition, the hybrids provide different operational characteristics to the resulting devices. The combination of graphene oxide with the light-absorbing polymer provides photovoltaic properties, whereas the adding of nickel transforms the hybrid into the monopolar conductive layers. The combination of two chromophores gives a multipurpose nanoelement, which performs as either non-linear resistor, diode or photodiode. This strategy can be easily extended to other combinations of chemical tools for the design of various hybrid nanofilms with desirable functional properties for organic electronics.
Facile Constructing Inorganic Phosphorus/boron-layered Double Hydroxide Complexes for Highly Efficient Fire-safety Epoxy Resin
Authors: Shao Zhu-Bao , Wang Tian-Ci , Song Xiang , Cui Jing , Zhu Longxiang , Lin Xue-Bao 
Published: September 2022

Abstract
Concerning inorganic flame retardants, the facile fabrication and high-efficiency fire safety without compromising the mechanical property of matrix are still significant challenges. Here, nano-layered double hydroxide containing boron constructed on the surface of ammonium polyphosphate complexes (B-LDH@APP) is prepared by a simple in-situ coprecipitation technology to reduce the fire hazard and improve mechanical performances of epoxy resin (EP). The as-obtained 4B-LDH@APP/EP achieves the UL-94 V-0 rating and presents superior flame-safety performance. With respect to the 4APP/EP, the fire growth rate, the peak heat release rate, and the peak smoke production rate of 4B-LDH@APP/EP decrease by 77.8%, 57.3%, and 52.6%, respectively. The reason is mainly contributed to excellent synergistic flame-retardant effect among boron, LDH, and APP, which can accelerate the generation of compact charring residual with good microstructure during combustion of B-LDH@APP/EP composites. Furthermore, B-LDH@APP slightly affects the mechanical performances of EP matrix due to the upgraded interfacial interaction.
A novel image encryption scheme for DNA storage systems based on gene hybridization and gene mutation
Authors: Yao Xiangyu , Xie Ranze , Zan Xiangzhen , Su Yanqing , Xu Peng , Liu Wenbin 
Published: September 2022

Abstract
With the rapid development of DNA (Deoxyribonucleic Acid) storage technologies, storing digital images in DNA is feasible. Meanwhile, the information security in DNA storage system is still a problem to solve. Therefore, in this paper, we propose a DNA storage-oriented image encryption algorithm utilizing the information processing mechanisms in molecule biology. The basic idea is to perform pixel replacement by gene hybridization, and implement dual diffusion by pixel diffusion and gene mutation. The ciphertext DNA image can be synthesized and stored in DNA storage system after encryption. Experimental results demonstrate it can resist common attacks, and shows a strong robustness in against sequence loss and base substitution errors in the DNA storage channel.
Phase transformation induced high-strength titanium carbide reinforced stainless steel composites with stable thermo-mechanical properties for high temperature applications
Authors: Cho Seungchan , Kim Junghwan , Lee Jihye , Shin Sangmin , Lee Donghyun , Kim Minsoo , Hong Hyun-Uk , Choi Moonhee , Lee Yoon-Seok , Jo Ilguk , Lee Sang-Kwan 
Published: September 2022

Abstract
The high-temperature properties such as the tensile strength, hardness, coefficient of thermal expansion (CTE), and thermal conductivity of titanium carbide (TiC)-reinforced stainless steel (SS) matrix composites fabricated by the infiltration process were investigated at various temperatures. Highly concentrated, closely adjacent TiC particulate reinforcement effectively suppressed dramatic variations in the CTE and thermal conductivity properties originating from the phase transformation of the SS431 matrix with superior mechanical properties. The strengthening effect of the addition of TiC increased as the temperature increased and showed a higher value after the phase transformation. The TiC–SS431 composite showed great applicability for advanced high-temperature-resistant structural materials.
Ocean response to Tropical Cyclone “Asani”: Surface cooling restricted by Coastal Downwelling
Authors: Ray Sthitapragya , Moharana Sidha Sankalpa , Swain Debadatta 
Published: September 2022

Abstract
The severe cyclonic storm “Asani” formed in the southeastern Bay of Bengal on 6th May 2022 and made landfall on the evening of 11th May 2022 in Andhra Pradesh, India. The unique characteristic of this cyclone was its low TS from roughly 27 hours prior to its landfall resulting in a remarkably prolonged interaction with the coastal ocean. In this analysis, we examined the sea surface temperature (SST) response to the cyclone at three locations along its track and analyzed the temporal variation of the observed cyclone-driven SST cooling. Four different ocean processes (wind-stirred and buoyancy flux-driven mixing, windstress-curl and alongshore windstress driven upwelling) could be identified by the corresponding proxies as the drivers of this cooling. A SST cooling of 1.08 °C was observed over a two-day period around the genesis area. Ekman pumping and wind-stirred mixing illustrated high values over the maximum intensity region during the passage of the cyclone, resulting in a SST drop by 2.14 °C. The landfall area had a significantly longer duration of interaction with the cyclone, as its TS reduced from moderate to slow, exhibiting wind-stirred mixing values comparable to the other two regions. However, the SST drop was the lowest at ~0.65 °C. Coastal downwelling-favourable windstress associated with the leading edge of the cyclone was responsible for limiting the cooling that could have otherwise resulted from mixing and entrainment. This unique modification of cyclone-ocean interaction through coastal upwelling possibly delayed the dissipation of cyclone “Asani”.
β-cypermethrin and essential oils incorporated into a single nanoformulation: chemical and biological characterization
Authors: Jesser Emiliano Nicolas , Yeguerman Cristhian Alan , URRUTIA Rodrigo Iñaki , MURRAY Ana Paula , Domini Claudia , González Jorge Omar Werdin 
Published: September 2022

Abstract
This work developed and evaluated the toxicological effects of single nanoemulsions (NEs) of peppermint or palmarosa essential oils (EO) combined with β-cypermethrin (CP) using ultrasound technique. For NEs formulation ultrasound parameters were: ultrasound power = 65 W, sonication time = 2 min and cycles = 30 on/20 off. The optimized active ingredients:surfactant ratio was 1:2. The NEs of peppermint EO combined with CP showed two peaks at 12.77 (33.4% intensity) and 299.1 nm (66.6% intensity) and polydisperse index (PDI) values of 1, while the NEs of palmarosa EO combined with CP had a size of 104.5 nm and their PDI value, 0.220. Both NEs were transparent and they were stable for 2 months. The insecticidal effect of these NEs (active ingredients:surfactant ratio was 1:2) were evaluated against T. castaneum and S. oryzae adults and Cx p. pipiens larvae. The NEs of peppermint EO combined with CP showed an enhancement of bioactivity of β-CP between 4.22 and 16 folds, while NEs of palmarosa EO + CP between 3.90 and 10.6 folds in all these insects. Moreover, both NEs demonstrated high insecticidal activity in all insect for 2 months, although slightly increase of particle size was detected. In this regard, the NEs elaborated in this work can be considered as highly promising formulation for the development of new insecticides.
The Kangjiapo landslide in Wanzhou district, Chongqing city: reactivation of a deep-seated colluvial landslide in the Three Gorges Reservoir
Authors: Xie Xiaoxu , Li Deying , Miao Fasheng , Yan Liangxuan , Leo Chin , Yiqing Sun 
Published: September 2022

Abstract
How to reduce landslide risk economically and effectively is a very meaningful and challenging research topic. In particular, it is difficult and expensive to completely control deep-seated colluvial landslides. Taking the Kangjiapo landslide in Wanzhou district, Chongqing city, China as a case, this study focuses on measures to prevent and control the risks of deep-seated colluvial landslides through detailed investigation and monitoring. The Kangjiapo landslide is located in the Three Gorges Reservoir area, and it is part of a famous ancient landslide named the Pipaping landslide. The steep sliding surface in the rear was not found during the first treatment, the Kangjiapo landslide has been reactivated since 2015. Field investigations, monitoring, borehole and related test were conduct to identify the landslide characteristics and mechanisms. The landslide deformation was not spatially or temporally uniform according to monitoring data analysis. The landslide is less likely to fail in general because the sliding surface in the front is very gentle. The reasons for Kangjiapo landslide reactivation could include the decline of the reservoir water level, a steep sliding surface in the rear, the existence of a sliding zone with low strength due to a long period of reservoir immersion. Landslide risk mitigation measures are proposed for the deep-seated landslide, including stabilizing piles nearby the road, and a BeiDou Navigation Satellite System and MEMS inclinometers in the platform.
Zinc finger DHHC-type palmitoyltransferase 12 is a potential prognostic biomarker in glioma
Authors: Xu Haitao , Chen Xi , Niu Xiaoqun , Pu Jun 
Published: September 2022

Abstract
Background
Zinc finger aspartate - histidine - histidine - cysteine (DHHC) - type palmitoyltransferase 12 (ZDHHC12) is reportedly involved in neuropsychiatric diseases. However, the biological function and mechanism of ZDHHC12 in glioma remain to be further explored. Hence, this study aimed to investigate the associations between ZDHHC12 expression and prognosis and tumor progression in glioma.
Methods
We utilized the cancer genome atlas (TCGA) and Chinese Glioma Genome Atlas (CGGA) databases to explore the expression level and prognostic value of ZDHHC12 in glioma. Furthermore, GO, KEGG and GSEA enrichment analysis were used to examine the function of ZDHHC12 in glioma. The ESTIMATE and ssGSEA algorithms were used to explore the correlations between ZDHHC12 expression and tumor-infiltrating immune cells. Finally, immunohistochemistry, growth curves, EdU, Transwells and wound healing assays were used to examine the biological function of ZDHHC12 in glioma cell lines.
Results
Higher expression of ZDHHC12 was correlated with adverse clinical features, including tumor grade, IDH status, 1p/19q depletion, histological type and patient age. Moreover, increased ZDHHC12 expression was associated with poorer overall, disease-specific, and progression-free survival. ZDHHC12 expression was strongly associated with immune cell infiltration in glioma. Importantly, ZDHHC12 was highly expressed in glioma tissues and depletion of ZDHHC12 significantly inhibited glioma cell proliferation and migration and promoted glioma cell apoptosis in vitro.
Conclusion
We found that ZDHHC12 was upregulated and could act as a poor prognostic biomarker in glioma. Importantly, ZDHHC12 expression was associated with the immune infiltration levels of immune cells in glioma. In addition, depletion of ZDHHC12 significantly inhibited glioma cell proliferation and migration and promoted glioma cell apoptosis in vitro. These findings suggested that ZDHHC12 might be a potential biomarker for evaluating prognosis and immune infiltration in glioma.
Lipid droplets’ functional protein caveolin-2 is associated with lipid metabolism-related molecule FABP5 and EMT marker E-cadherin in oral epithelial dysplasia
Authors: Chen Xiao-Jie , Bai Yu-Ting , Xie Ji-Rong , Zhou Gang 
Published: September 2022

Abstract
Background: The function of lipid droplets (LDs) has not been clarified in precancerous lesions, and the relationship between LDs, lipid metabolism, and epithelial-mesenchymal transition (EMT) remains unclear in the carcinogenesis processes in the oral cavity.Methods: Tissue frozen sections were collected for oil red O staining of LDs. Forty-eight oral squamous cell carcinomas (OSCC), 78 oral potentially malignant disorders (OPMDs), and 25 normal paraffin-embedded tissue sections were included to explore the LDs surface protein caveolin-2 and perilipin-3, lipid metabolism-related molecule fatty acid binding protein 5 (FABP5), and EMT biomarker E-cadherin expression by immunohistochemical staining. Results: The accumulation of LDs was observed in OPMDs and OSCCs compared to normal tissues (P < 0.05). In general, an increasing trend of caveolin-2, perilipin-3, and FABP5 expression was detected from the normal to OPMDs to OSCC groups (P < 0.05); however, the increased level of perilipin-3 was not significant in OPMDs compared to the normal controls (P > 0.05). In addition, caveolin-2, perilipin-3, and FABP5 expression were positively correlated with epithelial dysplasia in OPMDs, whereas E-cadherin positivity was negatively correlated with epithelial dysplasia and histopathological grade in OPMDs and OSCC, respectively. A negative correlation of caveolin-2 (P < 0.01, r = - 0.1739), and FABP5 (P < 0.01, r = - 0.1880) with E-cadherin expression was detected. The caveolin-2 (P < 0.0001, r = 0.2641) and perilipin-3 (P < 0.05, r = 0.1408) staining was positively correlated with FABP5. OSCC local recurrence was associated with high expression of caveolin-2 (P < 0.05) and FABP5 (P < 0.05), and lymph node metastasis was associated with high FABP5 expression (P < 0.05) but low E-cadherin expression (P < 0.05). The caveolin-2 high expression group had a worse disease-free survival (DFS) (P < 0.05). Conclusion: In the oral epithelial carcinogenesis process, LDs begin to accumulate early in the precancerous stage. LDs may be the regulator of FABP5-associated lipid metabolism and are closely related to the process of EMT; caveolin-2 could be the main functional protein, indicating that caveolin-2 is a potential biomarker for oral carcinogenesis and prognosis.