bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pityriasis rubra pilaris with erythema gyratum repens-like eruption and resolution with ustekinumab
Authors: Wong Jo-Yve , Surgenor Laura , McCourt Collette 
Published: August 2022

Abstract
Erythema gyratum repens (EGR) is a rare paraneoplastic disorder often preceding the diagnosis of underlying malignancy by 9 months on average, while pityriasis rubra pilaris (PRP) is an uncommon papulosquamous inflammatory disease. We present the case of a 58-year-old woman with an EGR-like eruption transforming from resolving PRP, without associated malignancy. Her rash dramatically resolved within a month of ustekinumab initiation, which supports this presentation as a unique entity.
Linking life history to landscape for threatened species conservation in a multiuse region
Authors: Shaw Robyn E. , Spencer Peter B. , Gibson Lesley A. , Dunlop Judy A. , Kinloch Janine E. , Mokany Karel , Byrne Margaret , Moritz Craig , Davie Harriet , Travouillon Kenny J. , Ottewell Kym M. 
Published: August 2022

AbstractLandscape‐scale conservation that considers metapopulation dynamics will be essential for preventing declines of species facing multiple threats to their survival. Toward this end, we developed a novel approach that combines occurrence records, spatial–environmental data, and genetic information to model habitat, connectivity, and patterns of genetic structure and link spatial attributes to underlying ecological mechanisms. Using the threatened northern quoll (Dasyurus hallucatus) as a case study, we applied this approach to address the need for conservation decision‐making tools that promote resilient metapopulations of this threatened species in the Pilbara, Western Australia, a multiuse landscape that is a hotspot for biodiversity and mining. Habitat and connectivity were predicted by different landscape characteristics. Whereas habitat suitability was overwhelmingly driven by terrain ruggedness, dispersal was facilitated by proximity to watercourses. Although there is limited evidence for major physical barriers in the Pilbara, areas with high silt and clay content (i.e., alluvial and hardpan plains) showed high resistance to dispersal. Climate subtlety shaped distributions and patterns of genetic turnover, suggesting the potential for local adaptation. By understanding these spatial–environmental associations and linking them to life‐history and metapopulation dynamics, we highlight opportunities to provide targeted species management. To support this, we have created habitat, connectivity, and genetic uniqueness maps for conservation decision‐making in the region. These tools have the potential to provide a more holistic approach to conservation in multiuse landscapes globally.
A myeloperoxidase enhancer drives myeloid cell‐specific labeling in a transgenic frog line
Authors: Yamada‐Kondo Shiori , Ogawa Ayame , Fukunaga Miku , Izutsu Yumi , Kato Takashi , Maéno Mitsugu 
Published: August 2022

AbstractWe have identified a myeloid cell‐specific enhancer in the 5′ flanking region of the Xenopus tropicalis myeloperoxidase gene. Transgenic reporter analysis using Xenopus laevis revealed that the expression of GFP was detected in the tail fin macrophages of a swimming tadpole, and the distributions of the GFP‐positive and XL‐2 (a pan‐marker for leukocytes)‐positive cells were mostly overlapping. The GFP‐positive cells in the liver of the transgenic tadpole were localized in the same areas where the myeloid cells were present. Isolation of leukocytes from the peripheral blood cells followed by flow cytometric analysis revealed that the GFP‐positive fraction was specifically enriched in neutrophils with lobulated nuclei. Furthermore, the macrophages purified from the peritoneal cavity were also GFP‐positive. In summary, a transgenic frog line in which the myeloid cells are labeled with GFP provides a useful tool to elucidate the physiological role of myeloid cells of multiple origins in the embryo.
Intravital staining to detect mineralization in Xenopus tropicalis during and after metamorphosis
Authors: Nakajima Keisuke , Yabumoto Souta , Tazawa Ichiro , Furuno Nobuaki 
Published: August 2022

AbstractObserving mineralization is essential for studying skeletal development, maintenance, and regeneration. Calcein and alizarin red have long been used to visualize mineralization in fixed specimens, but this requires the target animals to be sacrificed. However, several intravital bone‐staining methods have been developed to visualize mineralized tissues in living animals. These methods have been applied to study fin rays and transparent fishes. Xenopus tropicalis is an excellent experimental animal model for studying bone formation and regeneration because skeletal mineralization begins during the free‐living tadpole period, and its regenerative ability changes during metamorphosis. However, intravital bone staining of X. tropicalis has only been reported for tadpoles, and no details on its specificity or appropriate experimental conditions are available. Here, we compared the calcein‐ and alizarin red S (ARS)‐staining methods and optimized these methods for tadpoles and juvenile frogs during and after metamorphosis. Staining with 0.01% ARS yielded acceptable signaling for young tadpoles, whereas calcein either at 0.1 or 0.01% occasionally showed artifactual staining of unmineralized tissues. In addition, 0.1% calcein or 0.1% ARS staining showed a higher signal‐to‐noise ratio with juvenile frogs compared to staining at 0.01%. We propose the use of 0.01% ARS for tadpoles before stage 61 and 0.1% ARS thereafter for staining mineralized tissues. Using this method, we found that ossification of the neural arches occurred at stage 51 in X. tropicalis. This method enables precise staging and manipulation based on the visualized bone structure.
Caregiver‐reported psychological and behavioural functioning of children with suicidal thoughts and behaviour: A case–control design
Authors: Bartolini Ellen , Ostrander Rick , Parrish Carisa , Van Eck Kathryn , Grados Marco , Reynolds Elizabeth K. 
Published: August 2022

AbstractObjectiveThis exploratory project aims to provide an empirical understanding of the caregiver‐reported emotional and behavioural functioning of children 12 and under who present to an inpatient psychiatric unit with suicidal ideation and/or attempts.MethodA retrospective chart review was conducted, including all patients (n = 573) aged 12 and under admitted to a psychiatric inpatient unit between September 2011–December 2015 for suicidal ideation without proximal attempt (n = 155) or a suicide attempt (n = 37). Inpatients without suicidal thoughts and behaviour in the same age range (n = 381) served as a control group. The three groups were compared on a range of variables, including patient history/demographics, caregiver‐reported emotional/behavioural functioning, and discharge diagnoses.ResultsChildren who were admitted to a psychiatric inpatient unit following suicide attempts and/or ideation demonstrated clinically significant levels of externalizing and internalizing symptoms. Children with suicidal thoughts and behaviour (STB) were more likely to be female and older than their peers without STB, more likely to report a history of sexual abuse and non‐suicidal self‐injury, and to be diagnosed with a depressive disorder.ConclusionsChildren with STB differ demographically, symptomatically, and diagnostically from their peers without STB with comparable levels of psychiatric impairment (i.e., necessitating inpatient admission). Results provide provisional information on this concerning group of children, which can be used to aid identification of risk factors, inform treatment, and stimulate future work.
Ethnic diversity in academic dentistry in the United Kingdom
Authors: Burns Lorna , Coelho Cathy , Addy Amanda 
Published: August 2022

AbstractCareers in academic dentistry are failing to attract a new generation of academics to steer dental education and research. Dental academia is further limited by inadequacies in levels of ethnic diversity. There is a stark contrast between the diversity of graduates entering the dental profession and those in academic positions, especially in senior ranks. Dentistry is not the only field in academia, which lacks representation and lessons may be drawn from other faculties. This paper focuses on what is known about dental academia in the United Kingdom, where there are formal research training pathways. There is an emerging recognition of the requirement for action, and it is hoped this will stimulate debate and impetus for research across Europe. The terminology used throughout this piece follows the United Kingdom Cabinet Office recommendations for writing about ethnicity (Writing about ethnicity, 2021; https://www.ethnicity‐facts‐figures.service.gov.uk/style‐guide/writing‐about‐ethnicity). Where cited sources have employed less acceptable terms (Please don't call me BAME or BME!: Civil service, 2019; https://civilservice.blog.gov.uk/2019/07/08/please‐dont‐call‐me‐bame‐or‐bme/), these have been changed.
Development of a predictive model using the Kihon Checklist for older adults at risk of needing long‐term care based on cohort data of 19 months
Authors: Sato Kanae , Ishii Shinya , Moriyama Michiko , Zhang Junyi , Kazawa Kana 
Published: August 2022

AimThis study developed a risk scoring tool and examined its applicability using data from the Kihon Checklist cohort dataset for 19 months to predict the transition from no certification for long‐term care to long‐term care level 3 or above.MethodsData were collected from 26 357 functionally independent, community‐dwelling older adults in a Japanese city who answered the Checklist in 2014 and were followed for 19 months. Individuals certified for long‐term care during the follow‐up period were classified into three levels depending on their certification status: low, moderate, and high long‐term care levels. Relationships between the Kihon Checklist domains and high long‐term care levels were examined using the logistic regression model. A score chart predicting incidents of high long‐term care levels was created to facilitate its applicability.ResultsAs of 2016, 971 participants were certified for long‐term care (3.7%), of which 168 (0.6%), 357 (1.4%), and 446 (1.7%) were certified as high, moderate, and low long‐term care levels, respectively. Variables associated with the certification of high long‐term care level included difficulties in activities of daily living, a decline in locomotor and cognitive function in the Kihon Checklist domains, and age. The score chart was created based on these variables and demonstrated excellent discriminatory ability, with an area under curve of 0.817 (95% confidence interval: 0.785–0.849).ConclusionsThe Kihon Checklist can predict the future development of a high degree of dependency. The score chart we developed can be easily implemented to identify older adults at high risk with reasonable accuracy. Geriatr Gerontol Int 2022; 22: 797–802.
Association between diabetic peripheral neuropathy and sarcopenia: A systematic review and meta‐analysis
Authors: Wannarong Thapat , Sukpornchairak Persen , Naweera Weerakit , Geiger Christopher D. , Ungprasert Patompong 
Published: August 2022

AimThe present study comprehensively investigated the relationship between diabetic peripheral neuropathy (DPN) and sarcopenia by identifying all eligible studies and summarizing their results.MethodsRecords were identified through MEDLINE and EMBASE database searching from inception to March 9, 2022. We included all cross‐sectional studies investigating the association between DPN and sarcopenia among patients with diabetes. Data from eligible studies, including point estimates and standard errors, were pooled together using the generic inverse variance method.ResultsOf 2989 retrieved articles, five studies met the inclusion criteria and were allowed for meta‐analysis. The pooled analysis found a significant association between DPN and sarcopenia with the pooled odds ratio of 1.62 (95% confidence interval: 1.30–2.02; I2 0%). The funnel plot was relatively symmetric and was not suggestive of the presence of publication bias.ConclusionsThe current study discovered a significant association between DPN and sarcopenia in patients with diabetes. However, given summarized data from cross‐sectional studies, the temporality between DPN and sarcopenia could not be established. Geriatr Gerontol Int 2022; 22: 785–789.
Understanding of the residual odour of fatty esters used as emollient in cosmetic products
Authors: Jaricot Marie , Malhiac Catherine , Chao Christina , Merlaud Fabien , Grisel Michel , Savary Géraldine 
Published: August 2022

AbstractObjectiveFatty esters are known for their versatility, but in addition to their performance as emollients, emulsifiers, solubilizers, or dispersing agents, they have to meet more and more criteria to be used in cosmetic products. Thus, their olfactory characteristics are expected to be as neutral as possible. However, despite a step of deodorization during the synthesis of fatty esters, a residual odour is currently still perceived at the end of the process.MethodsIn this study, a specific analytical methodology combining sensory with chemical analyses was implemented to characterize the residual odour of two fatty esters and to determine its origin. Ethyl oleate and isononyl isononanoate were selected and underwent a sensory analysis to evaluate their odour intensity and odour profile. Volatile compounds released by these esters were assessed by GC–MS after solid‐phase microextraction and among them, odouractive compounds were brought into light using gas chromatography coupled with mass spectrometry and olfactometry analyses.ResultsOn the isononyl isononanoate chromatogram, only peaks corresponding to the different isomeric ester forms were evidenced while around 70 volatile compounds were detected in the ethyl oleate headspace, including esters, aldehydes, hydrocarbons, and ketones. Isononyl alcohol used as raw material in the synthesis was proven to be responsible for isononyl isononanoate final odour. As for ethyl oleate, of the 23 odour‐active compounds perceived, 14 have been identified; they are mainly esters and saturated as well as unsaturated aldehydes.ConclusionA novel measurement approach was presented to analyse trace odours of fatty esters and the results will be useful to control their deodorization by targeting appropriate strategies with the aim to either avoid the formation or remove the identified odorant compounds. This study may be further expanded by investigating the impact of deodorization on odour‐active compounds for a complete understanding of their contribution to the fatty ester global odour.
Large‐scale preparation of nano‐sized carbides and metal whiskers via mechanochemical decomposition of MAX phases
Authors: Tian Zhihua , Xu Xueqin , Tang Jingwen , Zhang Qianqian , Wu Fushuo , Zhang Peigen , Liu Jian , Sun ZhengMing 
Published: August 2022

AbstractNano‐sized transition metal carbide powder is usually synthesized by chemical methods such as chemical vapor deposition, while its large‐scale synthesis is a long‐standing challenge due to high energy consumption and low yield; metal nanowires (NWs) (mainly noble metals) are usually prepared by wet chemistry, and more compositions and greener preparation routes for metal NWs are urgent to meet the needs of the high technology industry. Herein, MAX phases are mechanochemically decomposed, resulting in the fine corresponding binary M‐X carbides and the A‐site metal whiskers. This implies a feasible top‐down route for efficiently preparing fine carbides and high‐quality metal whiskers on large scale. Several example MAX phases (both 312 and 211) are selected to demonstrate the feasibility of this method. The carbides and metal whiskers are characterized by X‐ray diffractometer, scanning electron microscope, transmission electron microscopy, and energy‐dispersive X‐ray spectroscopy to identify their morphology, composition, and phase. The compositional diversity of MAX phases bodes that this would be a promising alternative avenue to preparing various nano‐sized carbides and single‐crystal metal whiskers.
Responses to ambivalence toward social networking sites: A typological perspective
Authors: Turel Ofir , Qahri‐Saremi Hamed 
Published: August 2022

AbstractA common assumption in prior research on social networking sites (SNS) has been that users' orientations toward SNS use are positioned somewhere along a bipolar, univalent continuum, stretching from negative to positive orientation. However, considering recent findings unfolding the intricacy and variety of SNS use patterns, such a linear conceptualization of users' orientations is too simplistic with limited ability to explain the intricate patterns of SNS use. To alleviate this deficiency in this paper, we draw on the ambivalence literature and explain that users can simultaneously experience both positive and negative orientations toward SNS use based on the positive and negative aspects of their SNS use experience. Focusing on post‐ adoptive SNS use context, we theorise archetypes of SNS users' attitudinal responses to ambivalence, and their associated behavioural outcomes in terms of SNS use patterns. We first follow a typological perspective and develop typologies of attitudinal and behavioural responses to ambivalence toward SNS use. Then, we offer six hypotheses that explain the relations between the archetypes of attitudinal responses to ambivalence toward SNS use and users' SNS use patterns. Lastly, we empirically test our hypotheses using latent profile analysis and ANCOVA applied to two‐wave data collected from 370 ambivalent SNS users. The findings support the hypotheses and validate our typologies. The findings ultimately point to likely choices from a range of post‐adoption SNS use patterns as plausible outcomes of SNS users' attitudinal responses to ambivalence.
Coordinating harvest planning and scheduling in an agricultural supply chain through a stochastic bilevel programming
Authors: Albornoz Víctor M. , Vera Patricio I. 
Published: August 2022

AbstractThis paper addresses a selective harvest planning problem in the context of a hierarchical agricultural supply chain, which integrates the definition of management zones for harvest planning, and the coordination between the producer and the wholesaler. The problem is represented through a stochastic bilevel program that allows the representation of the hierarchy between the producer (leader) and a wholesaler (follower). The producer decides planning and scheduling of the selective harvest for each homogeneous management zone into the resulting partition, and the wholesaler decides the amount to be acquired to satisfy demand requirements. At each decision level, a stochastic optimization model is proposed for representing the uncertainty in future crop yields, prices, and demands, using a finite set of scenarios. A reformulation of the bilevel model into a mixed‐integer linear program is provided using Karush–Kuhn–Tucker conditions and replacing the nonlinear complementary constraints allowing for the introduction of auxiliary binary variables and a big‐Mterm. This model was applied in a case study for selective harvesting of grapes with data collected from a farm located in the south central zone of Chile. Our research shows valuable results of the proposed methodology from a set of instances representing the behavior of both decision makers under uncertainty.
Parallel optimization over the integer efficient set
Authors: Younes Djellouli , Sarah Hamadou , Djamal Chaabane 
Published: August 2022

AbstractThis paper introduces a modified sequential version method for optimizing a linear function over an integer efficient set, as well as a new exact parallel algorithm. The performance of parallel programming in this context is clear and shown through different instances with different sizes. Each procedure builds a finite monotonous sequence of values for the main criterion to be optimized, in a reasonable amount of CPU execution time. This latter remains much better. For the first time, the Algerian IBNBADIS cluster—CERIST—was used with this type of problem. Significant results are obtained by both proposed techniques, particularly with the parallel one.
Tailoring critical Al concentration to form external Al2O3 scale on Ni–Al alloys by computational approach
Authors: Ross Austin , Shang Shun‐Li , Fang Huazhi , Lindwall Greta , Liu Xuan L. , Zhao Wei , Gleeson Brian , Gao Michael C. , Liu Zi‐Kui 
Published: August 2022

AbstractNickel (Ni)‐based superalloys for high‐temperature applications are often designed to form a continuous and slow‐growing oxide scale by adding Al and Cr and other beneficial elements. In the present work, the critical Al concentration in Ni–Al alloys needed to establish an α‐Al2O3 scale in contrast to internal oxide formation is predicted as a function of temperature by means of the CALPHAD approach coupled with models in the literature, which account for the thermodynamics and kinetics of oxidation. The present thermodynamic remodeling of the Ni–O system results in a better agreement with experimental data of oxygen solubility in Ni at high temperatures. The oxygen solubility is combined with kinetic parameters to determine oxygen permeability in Ni, and the critical Al concentration needed to establish an α‐Al2O3 scale at a given exposure temperature. Good agreement is found with available experimental data for both oxygen permeability and critical Al concentration, indicating the capacity of the CALPHAD approach to tailor oxidation resistance for materials of interest using thermodynamic and kinetic knowledge.
Preparation of liquid polycarbosilane containing vinyl ether group and its rapid curing through thiol‐ene click reaction
Authors: Wang Yuanjie , Gong Jian , Pei Xueliang , He Liu , Huang Zhengren , Huang Qing 
Published: August 2022

AbstractIn this study, an SiC ceramic precursor vinyl ether–grafted liquid polycarbosilane (VE–LHBPCS) with approximate formulas of [SiH1.95(OCH2CH2OCH = CH2)0.05CH2]n was designed and synthesized. In order to cross‐link the ceramic precursor via fast thiol‐ene click reaction. The VE–LHBPCS was mixed with 1‐wt% ultraviolet (UV) decomposable free radical initiator BAPOs and 7‐wt% bis‐thiol compound 1,6‐hexanedithiol. According to Fourier transform infrared spectroscopy spectroscopy and photolithography experiment, more than 80% vinyl ether group was consumed within 3 s, and photolithography pattern with clear boundary could be formed after UV irradiation for only 1 s. Even for the VE–LHBPCS mixture with a thickness of 4 mm, 20‐s UV irradiation was sufficient to cure it with smooth surface and regular edge. Thermal gravimetric analysis demonstrated that the UV‐cured VE–LHBPCS mixture had a ceramic yield of 70.0 wt% at 1000°C, which was 20 wt% higher than that of raw LHBPCS. After pyrolysis up to 1000°C, about 29.5% isotropic linear shrinkage associated with the precursor‐to‐ceramic conversion was observed, and black dense ceramic with a density of 2.49 ± 0.09 g/cm3 and a chemical formula of SiC1.01O0.18S0.04 was obtained. With increasing the pyrolysis temperature, the content of element S decreased and the diffraction peaks of β‐SiC became sharper and stronger.