bluuebunny/crossref_metadata_2025_split huggingface dataset:
Histomorphological changes between short and long days in ovary guanacos (Lama guanicoe)
Authors: Correa E Lina Maria , Moreno Ricardo D. , Riveros José Luis 
Published: November 2022

AbstractThis is the first morpho‐histological comparison of guanaco ovaries between reproductive (long‐days) and non‐reproductive (short‐days) seasons, and oestrogen receptor‐alpha (ERα) and beta (ERβ) detection. Different stages of follicle development were found in the cortical area, but no corpus luteum was detected. The size and frequency of antral follicles and large atretic follicles were higher in long‐day ovaries than short‐days, consistent with ovarian activity in this season. Differential expression of ERα and ERβ was observed in follicles at different stages of development between short and long days. These data reveal histological and molecular differences between reproductive and non‐reproductive seasons of guanaco ovaries.
Skin to origin of mesenteric artery study (STOMA): prospective study of distances between stoma location and proximal superior mesenteric artery
Authors: Cao Amy Millicent Yesheng , Farsi Ali Hasan , Aljifri Alia Abdullah , Gilmore Andrew James 
Published: November 2022

AbstractBackgroundTraditional siting of stomas, in the lower abdomen, has been guided by surgical dogma lacking evidence. In the lower abdomen, the combination of a thick and pendulous abdominal apron, can create a challenging and suboptimal site for a stoma. The anatomical determinant limiting delivery of a stoma to the abdominal skin is the distance of the SMA from the lower border of the pancreas. The aim of this cross‐sectional study was to compare the distance between the traditional stoma site, and upper abdominal stoma sites, to both the superior mesenteric artery (SMA) origin and SMA at the inferior border of the pancreas on abdominal computed tomography (CT).MethodsA cross‐sectional study at a single academic university hospital of adult patients who underwent abdominal CT in Australia.ResultsTwo hundred and thirteen patients were included. Stoma sites in the upper abdomen were 57‐76 mm shorter to the origin of the SMA and inferior border of the pancreas than those positioned at the traditional stoma site (P < 0.001). The mean panniculus thickness in the upper abdomen was 10 mm thinner than in the lower abdomen and increased with increasing BMI (P < 0.001). The ratio between the distance from the xiphisternum to umbilicus, and the umbilicus to pubic symphysis, was 1.10; this ratio increased with increasing BMI.ConclusionThe distance of the SMA to the skin is always shorter in the upper abdomen compared to the traditional stoma site. Consideration should be given to placing stomas in the upper abdomen, particularly in overweight or obese patients.
Impact of oral health integration training on children's receipt of oral assessment, fluoride varnish and dental services
Authors: Cohen‐Cline Hannah , Ahmed Jannate , Holtorf Megan , McKeane Laura , Bartelmann Sarah 
Published: November 2022

AbstractObjectivesTo evaluate the impact of an oral health integration training program on children's receipt of oral health and dental services in Southern Oregon.MethodsChildren under 19 years with at least 6 months of Medicaid enrolment and at least one healthcare visit from 2014 to 2018 were included. The treatment group included children with at least one visit with a trained provider (n = 5541); children with no visits with trained providers (n = 8273) were the control group. The percentage of the treatment group who received oral health assessments was calculated, and regression models were developed to estimate the difference in likelihood of receiving fluoride varnish and dental services between treatment and control groups.ResultsThe percentage of children receiving oral health assessments increased over time. Visiting a trained provider was consistently associated, each year, with a greater likelihood of receipt of fluoride varnish and preventive and diagnostic dental services but was not associated with treatment dental services or dental sealants.ConclusionsThis study reports evidence for the overall impact of an oral health integration training on children's receipt of oral and dental services. Health systems implementing these types of training strategies should consider how to reach specific underserved subgroups, increase paediatric dentists, and expand efforts to include older children.
Chronic kidney disease begets heart failure and vice versa: temporal associations between heart failure events in relation to incident chronic kidney disease in type 2 diabetes
Authors: Wu Mei‐zhen , Teng Tiew‐Hwa Katherine , Tay Wan‐Ting , Ren Qing‐wen , Tromp Jasper , Ouwerkerk Wouter , Chandramouli Chanchal , Huang Jia‐Yi , Chan Yap‐Hang , Teramoto Kanako , Yu Si‐Yeung , Lawson Claire , Li Hang‐Long , Tse Yi‐Kei , Li Xin‐li , Hung Denise , Tse Hung‐Fat , Lam Carolyn S. P. , Yiu Kai‐Hang 
Published: November 2022

AbstractAimTo investigate the interplay of incident chronic kidney disease (CKD) and/or heart failure (HF) and their associations with prognosis in a large, population‐based cohort with type 2 diabetes (T2DM).MethodsPatients aged ≥18 years with new‐onset T2DM, without renal disease or HF at baseline, were identified from the territory‐wide Clinical Data Analysis Reporting System between 2000 and 2015. Patients were followed up until December 31, 2020 for incident CKD and/or HF and all‐cause mortality.ResultsAmong 102 488 patients (median age 66 years, 45.7% women, median follow‐up 7.5 years), new‐onset CKD occurred in 14 798 patients (14.4%), in whom 21.7% had HF. In contrast, among 9258 patients (9.0%) with new‐onset HF, 34.6% had CKD. The median time from baseline to incident CKD or HF (4.4 vs. 4.1 years) did not differ. However, the median (interquartile range) time until incident HF after CKD diagnosis was 1.7 (0.5‐3.6) years and was 1.2 (0.2‐3.4) years for incident CKD after HF diagnosis (P < 0.001). The crude incidence of CKD was higher than that of HF: 17.6 (95% confidence interval [CI] 17.3‐17.9) vs. 10.6 (95% CI 10.4‐10.9)/1000 person‐years, respectively, but incident HF was associated with a higher adjusted‐mortality than incident CKD. The presence of either condition (vs. CKD/HF‐free status) was associated with a three‐fold hazard of death, whereas concomitant HF and CKD conferred a six to seven‐fold adjusted hazard of mortality.ConclusionCardiorenal complications are common and are associated with high mortality risk among patients with new‐onset T2DM. Close surveillance of these dual complications is crucial to reduce the burden of disease.
Evaluation of China's regional innovation capability based on simulated annealing projection pursuit model and nested fuzzy evaluation model
Authors: Ge Mina , Lin Hualiang 
Published: November 2022

AbstractRegional innovation capability is an important indicator of both regional innovative and long‐term development. The purpose of this study is to build an evaluation index system for regional innovation capability in order to identify regional differences and support innovation more effectively. After establishing a reasonable evaluation value for regional innovation capability, a combination of simulated annealing optimized projection pursuit (SA–PP) and N‐layer nested fuzzy comprehensive evaluation models is used to assess China's regional innovation capabilities. The results show that the SA–PP model effectively mitigates the risk of erroneous evaluation results caused by index weight uncertainty, resulting in a more reasonable, robust, and intelligent assessment of regional innovation capability. Furthermore, the nested fuzzy comprehensive evaluation model is capable of easily resolving the evaluation factor set's heterogeneity and multilayer problems. The most significant influences on China's regional innovation capability are knowledge acquisition and enterprise innovation. The comprehensive score of the proposed combinational evaluation model manifests that provinces with strong regional innovation capabilities are mainly concentrated in the southeast coastal regions. The research results allow for precise weight determination and object ranking.
Caregivers and interventionists: Developing a Dual Role Behaviors Scale for parents of children with autism spectrum disorders
Authors: Zhou Ting , Zhang Chang , Yi Chunli 
Published: November 2022

AbstractThe integration of the roles of caregivers and interventionists is important in parenting a child with autism spectrum disorder (ASD). However, an instrument to measure dual‐role behaviors is unavailable. This study developed and validated the Dual Role Behaviors Scale for parents of autistic children (DRBS‐A). Initial items were generated using the interview transcripts of a previous qualitative study. The initial scale was administered to 422 parents. Data were randomly halved to generate Samples 1 and 2. Exploratory factor analysis conducted using Sample 1 (autism spectrum disorder = 216) screened items based on factor loadings and explored the scale's structure. Confirmatory factor analysis (CFA) conducted with Sample 2 (N = 206) examined structural validity. Among the participants, 121 (Sample 3) derived from the two samples were followed up after 1 month to examine the test–retest reliability. Convergent validity was examined with another sample of 105 parents (Sample 4). The formal version of the DRBS‐A comprised 20 items across four dimensions: parental acceptance, parental disengagement, persistence in interventions, and punishment in interventions. The four‐factor structure with two higher order factors was supported by the CFA results (χ2 = 290.90, df = 165, CFI = 0.94, TLI = 0.93, RMSEA = 0.061, SRMR = 0.063). The subscales' test–retest reliabilities ranged from 0.61 to 0.78. The internal consistencies were satisfactory (Cronbach's αs: 0.67–0.93). Convergent validity was supported by correlations of the DRBS‐A dimensions with parental involvement and positive parenting practice. Other factors related to dual‐role behaviors were also explored. The DRBS‐A has good validity and reliability and can be used to explore the effects of role integration.
Fatigue response of additively manufactured as‐built 15‐5 PH stainless steel and effects of machining and thermal and surface treatments
Authors: Croccolo Dario , Bogojević Nebojša , De Agostinis Massimiliano , Fini Stefano , Olmi Giorgio , Robusto Francesco , Šoškić Zlatan , Ćirić‐Kostić Snežana 
Published: November 2022

AbstractAdditively produced 15‐5 PH stainless steel has wide industrial applications, but the combined effects of heat treatment, machining, and shot‐peening and their order have not been deeply investigated. This topic is addressed here by a 2‐by‐3 experimental plan that has involved S–N curve and fatigue limit determination, using vertically built cylindrical samples, tested under rotating bending. The obtained responses have been analyzed by an ANOVA‐based statistical approach for comparison of fatigue trends. Results indicate that heat treatment without machining may be even detrimental for fatigue due to embrittlement. Conversely, machining with subsequent shot‐peening, even without heat treatment, has a remarkable impact and leads to a doubled fatigue strength with respect to as‐built material. This strength is also quite close to that achievable for wrought material. The study has been completed by micrography and fractography, to reveal the dependence of microstructure, crack initiation sites, and failure mode on the performed treatments.
Critical thickness of polymer‐derived ceramic coatings with particulate fillers
Authors: Zhang Zhao , Bordia Rajendra K. , Peng Fei 
Published: November 2022

AbstractIn this study, we demonstrate a novel environmental barrier coating processed from polymer‐derived ceramics (PDCs) with homogeneously distributed sub‐micrometer Y2O3 as the filler. Under suitable conditions, dense and crack‐free coatings can be achieved for all the designed compositions with the volumetric content of Y2O3 varied from 45 to 93 vol%. To process the PDC SiC–Y2O3 composite coatings, Y2O3 particles and SiC liquid precursor were uniformly dispersed in hexane and then dip‐coated on SiC substrates. After cross‐linking at 250°C and heat‐treated at 900°C in argon, dense and crack‐free PDC SiC–Y2O3 composite coatings were formed. The effect of coating thickness and heat‐treatment temperature on the formation of cracks due to constrained pyrolysis was studied. The critical thickness for realizing crack‐free coatings of three compositions (i.e., 93, 77, and 45 vol% Y2O3) was studied for heat treatment from 1000 to 1300°C using atomic force microscope and scanning electron microscopy. As heat‐treatment temperature increases, the critical coating thickness decreases for the same coating compositions due to enhanced shrinkage at higher temperature. With higher Y2O3 content, the critical thickness of the coating increased. The inert Y2O3 particles reduce the amount of polymer leading to reduction in the overall constrained shrinkage of the coating during heat treatment.
Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients
Authors: Ochoa‐Ramírez Luis Antonio , Díaz‐Camacho Sylvia Paz , Mellado‐Corrales Samantha Nohemí , Muñoz‐Estrada Víctor Fernando , Ríos‐Tostado Juan José , Sánchez‐Zazueta Jorge Guillermo , Velarde‐Félix Jesús Salvador 
Published: November 2022

AbstractBackgroundVitiligo is an autoimmune disease that courses with skin depigmentation because of the destruction of melanocytes. Vitiliginous melanocyte is prone to damage because of oxidative stress which activates cellular stress response and the release of heat shock proteins such as HSP70 promoting immune activation against the melanocyte. Variants in HSP70 genes (HSPA) might alter their expression and thus modulate vitiligo susceptibility. Therefore, we sought to evaluate the role of the 5′ untranslated region HSPA1A G/C (rs1043618) and the exonic HSPA1B A/G (rs1061581) and HSPA1L T/C (rs2227956) gene variants in nonsegmental vitiligo.MethodsA total of 200 nonsegmental vitiligo patients and 208 age/gender‐matched healthy subjects were genotyped for rs1043618, rs1061581, and rs2227956 variants by PCR‐RFLP.ResultsVariants rs1043618 and rs1061581 were not associated with vitiligo susceptibility. On the other hand, the rs2227956 C allele and TC genotype were associated with protection against vitiligo. A similar effect was observed for the GAC haplotype. Any of the aforementioned HSP70 gene variants were associated with the clinical characteristics of vitiligo.ConclusionOur findings suggest that the HSPA1L rs2227956 gene variant might influence the susceptibility to vitiligo. Being the first study of HSP70 gene variants in vitiligo, further research is encouraged to corroborate these results.
Mental health challenges facing male survivors of child sexual abuse: Implications for mental health nurses
Authors: Viliardos Laura , Murphy Neil , McAndrew Sue 
Published: November 2022

AbstractChild sexual abuse (CSA) is an issue of epidemic proportions in the United Kingdom (UK) and an international public health problem. Evidence suggests that in the UK one in 20 children have been sexually abused, with one in three not telling anyone about it at the time of the abuse. Conservative estimates suggest that around one in six men have experienced sexual abuse before the age of 18. CSA has been correlated with the development of numerous mental health problems, abused men often displaying externalizing behaviours, including substance misuse, ‘risky’ sexual behaviours, anti‐social behaviour, and offending. This article reports on one aspect of a research study focusing specifically on male survivors of CSA and its effect on their mental health. Using narrative research, face‐to‐face interviews were used to collect the stories of four men who participated in the research. Interviews were audio‐recorded and transcribed verbatim. Analysis used a two‐phase approach; initially, each narrative was analysed as a whole, with an across transcripts analysis then being carried out identifying shared themes emerging from the individual stories. Whilst findings from the second phase of the analysis identify four themes, it is the theme of ‘Blocking the Memories’ that is the focus for this article. Making a valuable contribution to existent knowledge regarding the experiences of men who were sexually abused as children, this article will help to inform mental health practitioners who are likely to deliver care to male survivors of CSA.
An integrative review exploring the impact of Electronic Health Records (EHR) on the quality of nurse–patient interactions and communication
Authors: Forde‐Johnston Carol , Butcher Dan , Aveyard Helen 
Published: November 2022

AbstractAimTo explore how nurses' use of electronic health records impacts on the quality of nurse–patient interactions and communication.DesignAn integrative review.Data sourcesMEDLINE®, CINAHL®, PscyINFO, PubMed, BNI and Cochrane Library databases were searched for papers published between January 2005 and April 2022.Review methodsFollowing a comprehensive search, the studies were appraised using a tool appropriate to the study design. Data were extracted from the studies that met the inclusion criteria relating to sample characteristics, methods and the strength of evidence. Included empirical studies had to examine interactions or communication between a nurse and patient while electronic health records were being used in any healthcare setting. Findings were synthesized using a thematic approach.ResultsOne thousand nine hundred and twenty articles were initially identified but only eight met the inclusion criteria of this review. Thematic analysis revealed four key themes, indicating that EHR: impedes on face‐to‐face communication, promotes task‐orientated and formulaic communication and impacts on types of communication patterns.ConclusionResearch examining nurse–patient interactions and communication when nurses' use electronic health records is limited but evidence suggests that closed nurse–patient communications, reflecting a task‐driven approach, were predominantly used when nurses used electronic health records, although some nurses were able to overcome logistical barriers and communicate more openly. Nurses' use of electronic health records impacts on the flow, nature and quality of communication between a nurse and patient.ImpactThe move to electronic health records has taken place largely without consideration of the impact that this might have on nurse–patient interaction and communication. There is evidence of impact but also evidence of how this might be mitigated. Nurses must focus future research on examining the impact that these systems have, and to develop strategies and practice that continue to promote the importance of nurse–patient interactions and communication.Patient or Public contributionStudies examined within this review included patient participants that informed the analysis and interpretation of data.
Nurse‐led hospital‐to‐community care, clinical outcomes for people living with HIV and health‐related social needs
Authors: Moen Marik , Doede Megan , Johantgen Meg , Taber Deborah , Adesanya Ikmat , Werthman Emily , Friedmann Erika 
Published: November 2022

AbstractAimsTo evaluate whether patients with HIV enrolled in Linkage to Care (hospital‐based only) or Linkage to Care Plus (nurse‐led hospital‐to‐community transitional care) programmes fare better on clinical outcomes; and to investigate how factors such as substance use, mental health or health‐related social needs contribute to these outcomes.BackgroundSocial determinants of health contribute to poor HIV outcomes such that only 57% of people living with HIV have achieved the goal of viral suppression nationally, and 50% are retained in clinical care. The programmes evaluated here aimed to increase HIV appointment attendance, retention in care, viral suppression and decrease acute care utilization and mitigate social needs via hospital‐to‐community transitional support.DesignA retrospective observational cohort study.MethodsWe conducted a retrospective patient chart review abstracting data over three time periods between 2017 and 2020 to conduct this longitudinal programme evaluation.ResultsBoth programmes had meaningful effects on increasing HIV appointment attendance and viral suppression; Linkage to Care Plus experienced the largest gains. Older age was associated with viral suppression, and housing insecurity and mental health conditions were associated with increased emergency department utilization.ConclusionHospital‐only and nurse‐led hospital‐to‐community transitional care programmes can positively influence HIV care outcomes. There is a need for enhanced attention and accountability related to health‐related social needs, especially housing, and mental and behavioural health, to end the HIV epidemic.ImpactGlobally, we are striving to end the HIV epidemic with evidence‐informed interventions. The nurse‐led hospital‐to‐community and the hospital‐only interventions evaluated here improved HIV outcomes with most gains realized by the nurse‐led transitional care model. Integrating lessons from these programmes, with increased attention and accountability for addressing social needs, can improve practice and policies to achieve programmatic and national goals related to HIV and other diseases, and more critically, to meet the goals of the people we serve.Patient or public contributionPatients, staff and leadership at the University of Maryland Institute of Human Virology JACQUES Initiative and University of Maryland Medical Center THRIVE clinic contributed to the design and implementation of the programmes and informed the programme evaluation study.
Randomized clinical trial to assess the impact of oral intervention with cetylpyridinium chloride to reduce salivary SARS‐CoV‐2 viral load
Authors: Tarragó‐Gil Rosa , Gil‐Mosteo María José , Aza‐Pascual‐Salcedo Mercedes , Alvarez María Jesús Lallana , Ainaga Raquel Refusta , Gimeno Natalia Lázaro , Viñuales Roberto Fuentes , Fernández Yolanda Millán , Marco Jesica Montero , Bolsa Elena Altarribas , Sancho Jessica Bueno , Cajo Sonia Algarate , Perez‐Zsolt Daniel , Raïch‐Regué Dàlia , Muñoz‐Basagoiti Jordana , Izquierdo‐Useros Nuria , Pociello Vanessa Blanc , León Rubén , Peris Diana Serrano 
Published: November 2022

AbstractAimAerosols released from the oral cavity help spread the SARS‐CoV‐2 virus. The use of a mouthwash formulated with an antiviral agent could reduce the viral load in saliva, helping to lower the spread of the virus. The aim of this study was to assess the efficacy of a mouthwash with 0.07% cetylpyridinium chloride (CPC) to reduce the viral load in the saliva of Coronavirus disease 2019 (COVID‐19) patients.Materials and MethodsIn this multi‐centre, single‐blind, randomized, parallel group clinical trial, 80 COVID‐19 patients were enrolled and randomized to two groups, namely test (n = 40) and placebo (n = 40). Saliva samples were collected at baseline and 2 h after rinsing. The samples were analysed by reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR) and an enzyme‐linked immunosorbent assay test specific for the nucleocapsid (N) protein of SARS‐CoV‐2.ResultsWith RT‐qPCR, no significant differences were observed between the placebo group and the test group. However, 2 h after a single rinse, N protein concentration in saliva was significantly higher in the test group, indicating an increase in lysed virus.ConclusionsThe use of 0.07% CPC mouthwash induced a significant increase in N protein detection in the saliva of COVID‐19 patients. Lysis of the virus in the mouth could help reduce the transmission of SARS‐CoV‐2. However, more studies are required to prove this.