bluuebunny/crossref_metadata_2025_split huggingface dataset:
Jail break: Tallis and the prison of nature
Authors: Clark Thomas W. 
Published: November 2022

Abstract
In Freedom: An Impossible Reality, Ray Tallis argues that we escape imprisonment by causal determinism, and thus gain free will, by the virtual distance from natural laws afforded us by intentionality, a human capacity that he claims cannot be naturalized. I respond that we can’t know in advance that intentionality will never be subsumed by science, and that our capacities to entertain possibilities and decide among them are natural cognitive endowments that supervene on generally reliable neural processes. Moreover, any disconnection from the multi-level determinants that account for human behavior cannot augment, but would likely undermine, effective human agency. Our full inclusion in nature, understood in terms of a pragmatic, explanatory determinism, is therefore not a prison from which we need to escape.
Optimal block replacement policy for two-dimensional products considering imperfect maintenance with improved Salp swarm algorithm
Authors: Dong Enzhi , Cheng Zhonghua , Shuai Yue , Zhao Jianmin 
Published: November 2022

Abstract
Human society is entering Industry 4.0. Engineering systems are becoming more complex, which increases the difficulties in maintenance support work. Maintenance plays a very important role in the entire life cycle of a system, and in reality, maintenance is not always perfect, and its maintenance degree is between good as new and bad as old, which should be considered in the maintenance strategy. Under the framework of two-dimensional warranty, this work proposes an optimal two-dimensional block replacement strategy based on the minimum expected warranty cost. Two-dimensional block replacement maintenance is imperfect maintenance. The failure rate reduction method is used to describe the maintenance effect of two-dimensional block replacement. In case analysis, the grid search algorithm, genetic algorithm, particle swarm optimization algorithm, and improved salp swarm algorithm (SSA) are used to find the optimal warranty scheme for the laser module. The improved SSA can converge faster and find a warranty scheme that makes the warranty cost lower. Therefore, managers can use these results to reduce costs and get a win-win extended warranty cost. Rationalization suggestions are put forward for managers to make maintenance decisions through comparative analysis and sensitivity analysis.
Lead in traditional and complementary medicine: a systematic review
Authors: McRae Angus , Vilcins Dwan , Le Hong Huynh Thi Cam , Gorman Julia , Brune Drisse Marie Noel , Onyon Lesley , Sly Peter D. , Islam Mohammad Zahirul 
Published: November 2022

Abstract
Lead in the environment remains a matter of grave concern for public health. Lead has been associated with some traditional medicines and has been linked to cases of lead poisoning. A comprehensive compilation of these reports has not previously been conducted. The objective of this review is to explore how common is lead exposure after traditional medicine use, and which countries, systems and/or products are of most concern when it comes to lead contamination. A systematic search was conducted on PubMed, Ovid and EMBASE for studies published between 2005 and 2020. A grey literature search was conducted. Search terms related to lead and traditional medicine were developed for each database, and there were no limitations on language. Studies were included if they examined elevated lead in humans resulting from the use of traditional medicines reported in case reports, case-series, or observational studies. Of the papers discussing lead exposure, 85 case reports were identified and synthesized for the current review. Several themes were identified in the included studies. Traditional medicine has been used in the many parts of the world, however use is more common in South and Southeast Asian countries. The level of detectable lead in products varied widely by region and product types. Consumers of traditional medicines sought products for a wide variety of symptoms and ailments. The symptoms of lead poisoning from traditional medicine use reflected the typical symptom profile of lead poisoning, highlighting the need for awareness of traditional medicine products as a source of lead exposure. Traditional medicine usage remains an important part of health care in many regions, however there is a risk of lead exposure from several products. Health care practitioners in all regions of the world should be aware of the risk and explore the potential for traditional medicine use for patients presenting with elevated blood lead levels. Countries with a strong traditional medicine culture should explore policies for reducing lead exposure from traditional medicine products. JG, LO and MNBD are staff members of the World Health Organization. The authors alone are responsible for the views expressed in this publication and they do not necessarily represent the decisions, policy, or views of the World Health Organization.
Mixed-valent 1:1 oxidotellurates(IV/VI) of Na, K and Rb: superstructure and three-dimensional disorder
Authors: Völkl Hermann , Eder Felix , Stöger Berthold , Weil Matthias 
Published: November 2022

Abstract
Single crystals of three mixed-valent oxidotellurates(IV/VI) with general formula M
2TeIVTeVIO6 (H2O)
x
(M = Na, K, Rb) were grown under hydrothermal conditions at 210 °C from M
2CO3, TeO2 and Te(OH)6 in a 4:1:1 molar ratio. Na2Te2O6·11/8H2O (where TeIVTeVI is abbreviated as Te2) crystallizes as a monoclinic eightfold superstructure with occupational modulation of the water molecules. The structure is built of diperiodic corrugated [Te2O6]2− networks interleaved by the Na atoms and H2O molecules. The hexagonal crystal structures of M
2Te2O4(OH)4 (M = K, Rb; x = 2) with P63/mmc symmetry are made up of [Te2O4(OH)4]2− rods extending in the [001] direction. The rods are connected by the M atoms. The [TeIVO2(OH)2] units are disordered about the threefold axis, resulting in pronounced three-dimensional diffuse scattering.
The Toll pathway mediates Drosophila resilience to Aspergillus mycotoxins through specific Bomanins
Authors: Xu Rui , Lou Yanyan , Tidu Antonin , Bulet Philippe , Heinekamp Thorsten , Martin Franck , Brakhage Axel , Li Zi , Liégeois Samuel , Ferrandon Dominique 
Published: November 2022

AbstractHost defense against infections encompasses both resistance, which targets microorganisms for neutralization or elimination, and resilience/disease tolerance, which allows the host to withstand/tolerate pathogens and repair damages. In Drosophila, the Toll signaling pathway is thought to mediate resistance against fungal infections by regulating the secretion of antimicrobial peptides, potentially including Bomanins. We find that Aspergillus fumigatus kills Drosophila Toll pathway mutants without invasion because its dissemination is blocked by melanization, suggesting a role for Toll in host defense distinct from resistance. We report that mutants affecting the Toll pathway or the 55C Bomanin locus are susceptible to the injection of two Aspergillus mycotoxins, restrictocin and verruculogen. The vulnerability of 55C deletion mutants to these mycotoxins is rescued by the overexpression of Bomanins specific to each challenge. Mechanistically, flies in which BomS6 is expressed in the nervous system exhibit an enhanced recovery from the tremors induced by injected verruculogen and display improved survival. Thus, innate immunity also protects the host against the action of microbial toxins through secreted peptides and thereby increases its resilience to infection.
Disrupting metformin adaptation of liver cancer cells by targeting the TOMM34/ATP5B axis
Authors: Jin Ping , Jiang Jingwen , Zhou Li , Huang Zhao , Qin Siyuan , Chen Hai‐Ning , Peng Liyuan , Zhang Zhe , Li Bowen , Luo Maochao , Zhang Tingting , Ming Hui , Ding Ning , Li Lei , Xie Na , Gao Wei , Zhang Wei , Nice Edouard C , Wei Yuquan , Huang Canhua 
Published: November 2022

AbstractMetformin, a well‐known antidiabetic drug, has been repurposed for cancer treatment; however, recently observed drug resistance and tumor metastasis have questioned its further application. Here, we found that long‐term metformin exposure led to metabolic adaptation of hepatocellular carcinoma (HCC) cells, which was characterized by an obvious epithelial–mesenchymal transition (EMT) phenotype and compensatory elevation of oxidative phosphorylation (OXPHOS). TOMM34, a translocase of the outer mitochondrial membrane, was upregulated to promote tumor metastasis in response to metformin‐induced metabolic stress. Mechanistically, TOMM34 interacted with ATP5B to preserve F1FO‐ATPase activity, which conferred mitochondrial OXPHOS and ATP production. This metabolic preference for OXPHOS suggested a large requirement of energy supply by cancer cells to survive and spread in response to therapeutic stress. Notably, disturbing the interaction between TOMM34 and ATP5B using Gboxin, a specific OXPHOS inhibitor, increased sensitivity to metformin and suppressed tumor progression both in vitro and in vivo. Overall, this study demonstrates a molecular link of the TOMM34/ATP5B‐ATP synthesis axis during metformin adaptation and provides promising therapeutic targets for metformin sensitization in cancer treatment.
ACCEPTANCE ANALYSIS OF TECHNOLOGY-BASED PERSONNEL MANAGEMENT INFORMATION SYSTEMS (SIMPATIK) IN SUPPORTING THE IMPLEMENTATION OF E-GOVERNMENT IN THE SEMARANG CITY MANPOWER SERVICE
Authors: Majid Muhammad Nurkholis , Budiman Kholiq 
Published: November 2022

In this digital era, information technology has an important role for institutions, companies, communities, and governments. In carrying out the main tasks of the Semarang City Manpower Service, one of them is evaluating employee performance. In assessing the performance of the Semarang City Manpower Service employees using SIMPATIK which was developed by the Semarang City BKPP which was launched in 2018. Where the implementation of the new system needs to be evaluated further. This is due to the failure to implement e-government services, not because of the quality and capacity of the system, but because of the low user acceptance of these services. Thus, it is necessary to analyse the level of acceptance in using SIMPATIK services at the Semarang City Manpower Service whether it can be evaluated further. So that SIMPATIK can still exist to be used for various kinds of services contained in the application by ASN at the Semarang City Manpower Service. The method applied to data collection is the interview and questionnaire method. While the method applied to evaluate SIMPATIK is the Technology Acceptance Model (TAM) by applying four research variables, namely perceived usefulness (PU), perceived ease of use (PEOU), attitude toward using (ATU), and behavioural intentions (BI). To examine the data adopted the method of Structural Equation Model-partial Least Square (SEMPLS). The conclusion reached in this study is that all hypotheses developed in this study were accepted, except for PU on BI rejected because the value of T-Statistics (0.846) < T-Table (1.96) and P-Values were more than 0.05 with a value of 0.398 .
Immunomodulation for unexplained recurrent implantation failure: where are we now?
Authors: Genest Geneviève , Banjar Shorooq , Almasri Walaa , Beauchamp Coralie , Benoit Joanne , Buckett William , Dzineku Frederick , Gold Phil , Dahan Michael H , Jamal Wael , Jacques Kadoch Isaac , Kadour-Peero Einav , Lapensée Louise , Miron Pierre , Shaulov Talya , Sylvestre Camille , Tulandi Togas , Mazer Bruce D , Laskin Carl A , Mahutte Neal 
Published: November 2022

In brief
Immune dysfunction may contribute to or cause recurrent implantation failure. This article summarizes normal and pathologic immune responses at implantation and critically appraises currently used immunomodulatory therapies.

Abstract
Recurrent implantation failure (RIF) may be defined as the absence of pregnancy despite the transfer of ≥3 good-quality blastocysts and is unexplained in up to 50% of cases. There are currently no effective treatments for patients with unexplained RIF. Since the maternal immune system is intricately involved in mediating endometrial receptivity and embryo implantation, both insufficient and excessive endometrial inflammatory responses during the window of implantation are proposed to lead to implantation failure. Recent strategies to improve conception rates in RIF patients have focused on modulating maternal immune responses at implantation, through either promoting or suppressing inflammation. Unfortunately, there are no validated, readily available diagnostic tests to confirm immune-mediated RIF. As such, immune therapies are often started empirically without robust evidence as to their efficacy. Like other chronic diseases, patient selection for immunomodulatory therapy is crucial, and personalized medicine for RIF patients is emerging. As the literature on the subject is heterogenous and rapidly evolving, we aim to summarize the potential efficacy, mechanisms of actions and side effects of select therapies for the practicing clinician.
Collaborative to Increase Lethal Means Counseling for Caregivers of Youth With Suicidality
Authors: Leyenaar JoAnna K. , Tolpadi Anagha , Parast Layla , Esporas Megan , Britto Maria T. , Gidengil Courtney , Wilson Karen M. , Bardach Naomi S. , Basco William T. , Brittan Mark S. , Williams Derek J. , Wood Kelly E. , Yung Steven , Dawley Erin , Elliott Audrey , Manges Kirstin A. , Plemmons Gregory , Rice Timothy , Wiener Brandy , Mangione-Smith Rita 
Published: November 2022

BACKGROUND
The number of youth presenting to hospitals with suicidality and/or self-harm has increased substantially in recent years. We implemented a multihospital quality improvement (QI) collaborative from February 1, 2018 to January 31, 2019, aiming for an absolute increase in hospitals’ mean rate of caregiver lethal means counseling (LMC) of 10 percentage points (from a baseline mean performance of 68% to 78%) by the end of the collaborative, and to evaluate the effectiveness of the collaborative on LMC, adjusting for secular trends.

METHODS
This 8 hospital collaborative used a structured process of alternating learning sessions and action periods to improve LMC across hospitals. Electronic medical record documentation of caregiver LMC was evaluated during 3 phases: precollaborative, active QI collaborative, and postcollaborative. We used statistical process control to evaluate changes in LMC monthly. Following collaborative completion, interrupted time series analyses were used to evaluate changes in the level and trend and slope of LMC, adjusting for covariates.

RESULTS
In the study, 4208 children and adolescents were included—1314 (31.2%) precollaborative, 1335 (31.7%) during the active QI collaborative, and 1559 (37.0%) postcollaborative. Statistical process control analyses demonstrated that LMC increased from a hospital-level mean of 68% precollaborative to 75% (February 2018) and then 86% (October 2018) during the collaborative. In interrupted time series analyses, there were no significant differences in LMC during and following the collaborative beyond those expected based on pre-collaborative trends.

CONCLUSIONS
LMC increased during the collaborative, but the increase did not exceed expected trends. Interventions developed by participating hospitals may be beneficial to others aiming to improve LMC for caregivers of hospitalized youth with suicidality.
Vibrational Music Therapy with D/deaf clients
Authors: Palmer Russ C. , Ojala Stina 
Published: November 2022

D/deaf clients perceive music through their bodies. The music therapist needs various methods to appreciate these sensations. It is necessary to examine the instruments from a vibrational perspective. Also, listening to the client is more important than speaking. This article focuses on how non-verbal methods are more appropriate when working with clients who have a hearing loss. Vibrosensoric approach to music combined with touch-based communication methods (social-haptic communication) enhances a positive client response. As a deafblind music therapist, musical vibrations play an important role for me as well as for the client during a therapy process. Background noise and spoken language can sometimes mask the perception of musical tones from different types of instruments. Speech with music within GIM sessions renders the client unable to follow either music or storyline. This distorts the sounds in hearing aid devices. Therefore, the instrument selection within the therapy session needs to be considered from a vibratory aspect. Musical tones from the instruments can be felt in different parts of the body. In this case, the focus is not on how an instrument sounds but more on the vibrational sensations it produces.
Notes on the lifecycle and distribution of Sphodromantis gastrica (Stål, 1858) (Mantodea: Mantidae) in South Africa
Authors: Greyvenstein Bianca , Du Plessis Hannalene , Van den Berg Johnnie 
Published: November 2022

Sphodromantis gastrica (Stål) (Mantodea: Mantidae), also known as the African mantis, is suggested to be common and widespread in southern Africa. Limited information is available regarding the distribution of this species in South Africa and no information is available on its biology. The aim of this study was to determine the distribution of S. gastrica in South Africa based on historic insect collection records as well as to study its basic biology and developmental parameters under captive breeding conditions. A total of 153 South African museum records of Sphodromantis spp. were recorded during this study. These records indicated that S. gastrica occurred in all but two provinces of South Africa. The incubation time of the S. gastrica oothecae were approximately 10 weeks and each ootheca contained an average of 84 egg chambers. The mean fertility rate was 54.6% while the survival rate until adulthood was 41.8%. The numbers of nymphal instars until adulthood ranged between four and nine. The mean lifespan of S. gastrica individuals were approximately 332 days and females lived longer than males.
Directional Sensitivity of DAS and Its Effect on Rayleigh-Wave Tomography: A Case Study in Oxnard, California
Authors: Fang Jiaqi , Yang Yan , Shen Zhichao , Biondi Ettore , Wang Xin , Williams Ethan F. , Becker Matthew W. , Eslamian Dominic , Zhan Zhongwen 
Published: November 2022

AbstractDistributed acoustic sensing (DAS) provides dense arrays ideal for seismic tomography. However, DAS only records average axial strain change along the cable, which can complicate the interpretation of surface-wave observations. With a rectangular DAS array located in the City of Oxnard, California, we compare phase velocity dispersion at the same location illuminated by differently oriented virtual sources. The dispersion curves are consistent for colinear and noncolinear virtual sources, suggesting that surface-wave observations in most of the cross-correlations are dominated by Rayleigh waves. Our measurements confirm that colinear channel pairs provide higher Rayleigh-wave signal-to-noise ratio (SNR). For cross-correlations of noncolinear channel pairs, the travel time of each connecting ray path can still be obtained despite the lower SNR of Rayleigh wave signals. The inverted Rayleigh-wave dispersion map reveals an ancient river channel consistent with the local geologic map. Our results demonstrate the potential of DAS-based 2D surface-wave tomography without special treatment of directional sensitivity in areas where one type of wave is dominating or can be identified.
Comparing Various Machine Learning Algorithms for Sugar Prediction in Chickpea using Near-infrared Spectroscopy
Authors: Priyadarshi Madhu Bala , Sharma Anu , Chaturvedi K.K. , Bhardwaj Rakesh , Lal S.B. , Farooqi M.S. , Kumar Sanjeev , Mishra D.C. , Singh Mohar 
Published: November 2022

Background: Chickpea is the third major pulse produced globally, with 11.6 million tonnes produced per annum (Merga and Haji, 2019). Sugar alcohols, inulin, starch are all prebiotic carbohydrates found in chickpeas (Johnson et al., 2020). Near-Infrared (NIR) spectroscopy is a non-destructive, versatile and powerful analytical technique. Methods: Spectral data obtained from NIR spectroscopy requires application of various techniques to extract useful information from spectral data which is further used for building various models for prediction of physical or chemical components presents in agricultural crops. The main aim of this study is to apply various machine learning algorithms especially effective in predicting sugar concentration in chickpea. Sugar prediction models are developed using Linear Regression (LR), Artificial Neural Network (ANN), Random Forest (RF), Support Vector Regression (SVR) and Decision Tree Regression (DTR) algorithms. Performance of the models is evaluated using measures namely, Root Mean Square Error (RMSE), Residual Standard Error (RSE), Coefficient of Determination (R2) and Adjusted Coefficient of Determination (adjusted R2). Result: It was observed that, RF outperformed all other models in terms of accuracy for predicting sugar component from preprocessed spectra, with RMSE, RSE, R2 and adjusted R2 values of 0.054, 0.062, 0.954 and 0.937, respectively. The accuracy of the ANN model is similar to that of the RF, with minor differences in RMSE, RSE, R2 and adjusted R2 , values of 0.057, 0.067, 0.952 and 0.935.
Plant, bird, and mammal diversity of the Tomogrande field station, Vichada, Colombia
Authors: Estrada Villegas Sergio , Rivas Luz Dary , Barrera John Fredy , Correa Diego F. , Argüello Bernal Laura Sofía , Aldana Ana María , Casas Luisa Fernanda , Lozano-Balcázar Alejandro , Gómez-Bahamón Valentina , Gómez Camila , Bayly Nicholas , Jahn Alex E. , Quiñones Antonio , Corbett Eamon C. , Castro Francisco , Stevenson Pablo , Barrera Rivas Steven 
Published: November 2022

The Altillanura is a unique ecosystem within the Colombian Llanos, characterized by well-drained savannas and extensive riparian forests. The Altillanura harbors a rich assemblage of species, largely understudied and currently under threat by large-scale and unplanned agribusiness. Moreover, the number of public protected areas in the Colombian Llanos, particularly in the Altillanura, is insufficient to conserve the threatened habitats and species. Therefore, conservation efforts by private reserves are crucial for the protection of the region’s biodiversity. Here we present the first species list of the Tomogrande, a private nature reserve and scientific research field station in the municipality of Santa Rosalía, Vichada, Colombia. After ten years of ongoing research, we have recorded 299 species of plants, 189 species of birds, and 47 species of mammals. Compared to other private nature reserves in Vichada and the Tuparro National Park, the largest protected area in the region, Tomogrande makes a substantial contribution to the conservation of all three taxonomic groups. We advocate that better landscape planning and sustainable practices should become mandatory in the Altillanura to protect its biodiversity and the livelihoods of all stakeholders that inhabit this region.