bluuebunny/crossref_metadata_2025_split huggingface dataset:
Computer or human: a comparative study of automated evaluation scoring and instructors’ feedback on Chinese college students’ English writing
Authors: Chen Huimei , Pan Jie 
Published: December 2022

AbstractThe role of internet technology in higher education and particularly in teaching English as a Foreign language is increasingly prominent because of the interest in the ways in which technology can be applied to support students. The automated evaluation scoring system is a typical demonstration of the application of network technology in the teaching of English writing. Many writing scoring platforms have been developed and used in China, which can provide online instant and corrective feedback on students’ writing. However, the validity of Aim Writing, a product developed by Microsoft Research Asia, which claims to be the best tool to facilitate Chinese EFL learners, has not been tested in previous studies. In this mixed methods study, the feedback and effect of Aim Writing on college students’ writing will be investigated and compared to the instructor’s feedback. The results indicate that Aim Writing’s performance is insufficient to support all students’ needs for writing and that colleges should encourage a hybrid model that contains both AES and instructor’s feedback in writing.
Assessment of brain natriuretic peptide and copeptin as correlates of blood pressure in chronic hypertensive pregnant women
Authors: Okwor Chika J. , Adedapo Kayode S. , Bello Oluwasomidoyin O. , Meka Ijeoma A. , Okwor Chukwuemeka V. , Uche Chukwuemelie Z. , Nwajiobi Chiebonam E. , Nto-Ezimah Uloaku A. , Uchechukwu Chisom E. , Arum Ekene J. 
Published: December 2022

Abstract
Background
Hypertensive disorders of pregnancy including preexisting (or chronic) hypertension are the most common complication encountered during pregnancy that contribute significantly to maternal and perinatal morbidity and mortality. Brain natriuretic peptide (BNP) and copeptin have been investigated as biomarkers in various hypertensive disorders, but studies of their clinical value in chronic hypertensive pregnant women are sparce. This study aimed to assess the levels of BNP and copeptin in chronic hypertensive pregnant women and investigate their correlation with blood pressure (BP) in chronic hypertensive pregnant women in South Western Nigeria.

Methods
One hundred and sixty consenting pregnant women in their third trimester of pregnancy, grouped into those with chronic hypertension (n = 80) and normotensive (n = 80), were recruited for this cross-sectional study. Age and clinical characteristics were obtained, and blood was aseptically drawn for BNP and copeptin measurement using enzyme-linked immunosorbent assay. Data was analyzed with IBM SPSS ver. 20.0. Data was analyzed using Student t-test, chi-square, and Pearson correlation test as appropriate. Statistical significance was set at P < 0.05.

Results
The mean systolic BP (SBP) and diastolic BP (DBP) were significantly higher in pregnant women with chronic hypertension (158.30 ± 3.51 and 105.08 ± 2.47 mmHg, respectively) compared with normotensive pregnant women (100.72 ± 3.02 and 70.29 ± 1.96 mmHg, respectively). The mean levels of BNP and copeptin were higher in pregnant women with chronic hypertension (57.26 ± 3.65 pg/mL and 12.44 ± 1.02 pmol/L, respectively) compared with normotensive pregnant women (49.85 ± 2.44 pg/mL and 10.25 ± 1.50 pmol/L, respectively) though not statistically significant. Correlations observed between SBP and DBP with levels of BNP (r = 0.204, P = 0.200; r = 0.142, P = 0.478) and copeptin (r = − 0.058, P = 0.288; r = 0.045, P = 0.907) were not statistically significant.

Conclusions
There was no association between BP and the levels of BNP and copeptin in pregnant women with chronic hypertension who were already on antihypertensive treatment, with the implication that antihypertensive treatment may modulate BNP and copeptin release despite significantly elevated BP levels.
Integration of EVs into the smart grid: a systematic literature review
Authors: Sultan Vivian , Aryal Arun , Chang Hao , Kral Jiri 
Published: December 2022

AbstractIntegration of electric vehicles (EVs) into the smart grid has attracted considerable interest from researchers, governments, and private companies alike. Such integration may bring problems if not conducted well, but EVs can be also used by utilities and other industry stakeholders to enable the smart grid. This paper presents a systematic literature review of the topic and offer a research framework to guide future research and enrich the body of knowledge. The systematic literature review presented in this paper does not contain all the material available on this subject. It does, however, include most of the key publications readily available in a power-utility or technical-reference library together with some of the earlier papers in the field (the anchor papers). For this review, we selected appropriate digital sources (digital libraries and indexing systems; IEEE Xplore and Web of Science), determined the search terms, and conducted a broad automated search. This article also details the components of the research theme—EV integration into the smart grid—as well as its accompanying use cases. The analysis of the relevant papers indicated four types of key research concerns: power-grid, power-system, and smart-grid reliability and the impacts of changes on them. These results can help guide future research to further smart-grid development. Future research can also expand the reach of this research to address its limitations in scope and depth.
Microsurgery versus Microsurgery With Preoperative Embolization for Brain Arteriovenous Malformation Treatment: A Systematic Review and Meta-analysis
Authors: Sattari Shahab Aldin , Shahbandi Ataollah , Yang Wuyang , Feghali James , Xu Risheng , Huang Judy 
Published: December 2022

BACKGROUND:
Preoperative embolization has traditionally been regarded as a safe and effective adjunct to microsurgical treatment of brain arteriovenous malformations (bAVM). However, there is currently no high-level evidence to ascertain this presumption.

OBJECTIVE:
To compare the outcomes of microsurgery (MS) vs microsurgery with preoperative embolization (E + MS) in patients with bAVM through systematic review.

METHODS:
We searched MEDLINE, PubMed, and Embase. The primary outcome was bAVM obliteration. Secondary outcomes were intraoperative bleeding (mL), complications, worsened modified Rankin Scale (mRS), and mortality. The pooled proportions of outcomes were calculated through the logit transformation method. The odds ratio (OR) of categorical data and mean difference of continuous data were estimated through the Mantel-Haenszel and the inverse variance methods, respectively.

RESULTS:
Thirty-two studies met the eligibility criteria. One thousand eight hundred twenty-eight patients were treated by microsurgery alone, and 1088 were treated by microsurgery with preoperative embolization, respectively. The meta-analysis revealed no significant difference in AVM obliteration (94.1% vs 95.6%, OR = 1.15 [0.63-2.11], P = .65), mortality (1.7% vs 2%, OR = 0.88 [0.30-2.58], P = .82), procedural complications (18.2% vs 27.2%, OR = 0.47 [0.19-1.17], P = .10), worsened mRS (21.2% vs 18.5%, OR = 1.08 [0.33-3.54], P = .9), and intraoperative blood loss (mean difference = 182.89 [−87.76, 453.55], P = .19).

CONCLUSION:
The meta-analysis showed no significant difference in AVM obliteration, mortality, complications, worse mRS, and intraoperative blood loss between MS and E + MS groups. For AVMs where MS alone has acceptable results, it is reasonable to bypass unnecessary preoperative embolization given higher postoperative complication risk.
In Single-Level, Open, Posterior Lumbar Fusion, Does Transforaminal Lumbar Interbody Fusion or Posterolateral Fusion Lead to Better Outcomes?
Authors: Chanbour Hani , Steinle Anthony M. , Tang Alan R. , Gardocki Raymond J. , Abtahi Amir M. , Stephens Byron F. , Zuckerman Scott L. 
Published: December 2022

BACKGROUND:
Two common approaches for open, one-level, posterior lumbar fusions include transforaminal lumbar interbody fusion (TLIF) and posterolateral fusion (PLF) alone without an interbody.

OBJECTIVE:
To compare TLIF vs PLF alone in (1) discharge disposition, (2) return to work (RTW), and (3) patient-reported outcomes (PROs).

METHODS:
A single-center, retrospective cohort study was undertaken between October 2010 and May 2021, all with a 1-year follow-up and excluding patients with isthmic spondylolisthesis. Minimum clinically important difference for each PRO was used, which included Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI). Logistic/linear regression controlled for age, body mass index, disc height, flexion-extension movement, amount of movement on flexion-extension, and spondylolisthesis grade.

RESULTS:
Of 850 patients undergoing open, 1-level, posterior lumbar fusion, 591 (69.5%) underwent a TLIF and 259 (30.5%) underwent a PLF alone. Patients undergoing TLIF were younger (59.0 ± 11.3 vs 63.3 ± 12.6, P < .001), had higher body mass index (31.3 ± 6.6 vs 30.2 ± 12.6, P = .019), and more often had private insurance (50.3% vs 39.0%, P < .001). Regarding discharge disposition, no significance was found in multivariate regression (odds ratio = 2.07, 95% CI = 0.39-10.82, P = .385) with similar RTW between TLIF and PLF alone (80.8% vs 80.4%, P = .645) (odds ratio = 1.15, 95% CI = 0.19-6.81, P = .873). Regarding PROs, patients undergoing a TLIF had higher preoperative (6.7 ± 2.3 vs 6.4 ± 2.5, P = .046) and 3-month NRS-back pain (3.4 ± 2.6 vs 2.9 ± 2.5, P = .036), with similar 12-month NRS-back pain. Regarding NRS-leg pain, no differences were observed preoperatively (P = .532) and at 3 months (P = .808). No other significant differences were observed in ODI.

CONCLUSION:
TLIF patients had slightly higher NRS-back pain at baseline and 3 months, but similar NRS-leg pain, despite the added risk of placing an interbody. No differences were seen in discharge disposition, RTW, and 12-month pain scores and ODI.
Physiological Responses and Training Satisfaction During National Rollout of a Neurosurgical Intraoperative Catastrophe Simulator for Resident Training
Authors: Siler Dominic A. , Cleary Daniel R. , Tonsfeldt Karen J. , Wali Arvin R. , Hinson Holly E. , Khalessi Alexander A. , Selden Nathan R. 
Published: December 2022

BACKGROUND:
Systematic use of neurosurgical training simulators across institutions is significantly hindered by logistical and financial constraints.

OBJECTIVE:
To evaluate feasibility of large-scale implementation of an intraoperative catastrophe simulation, we introduced a highly portable and low-cost immersive neurosurgical simulator into a nationwide curriculum for neurosurgery residents, during years 2016 to 2019.

METHODS:
The simulator was deployed at 9 Society of Neurological Surgeons junior resident courses and a Congress of Neurological Surgeons education course for a cohort of 526 residents. Heart rate was tracked to monitor physiological responses to simulated stress. Experiential survey data were collected to evaluate simulator fidelity and resident attitudes toward simulation.

RESULTS:
Residents rated the simulator positively with a statistically significant increase in satisfaction over time accompanying refinements in the simulator model and clinical scenario. The simulated complications induced stress-related tachycardia in most participants (n = 249); however, a cohort of participants was identified that experienced significant bradycardia (n = 24) in response to simulated stress.

CONCLUSION:
Incorporation of immersive neurosurgical simulation into the US national curriculum is logistically feasible and cost-effective for neurosurgical learners. Participant surveys and physiological data suggest that the simulation model recreates the situational physiological stress experienced during practice in the live clinical environment. Simulation may provide an opportunity to identify trainees with maladaptive responses to operative stress who could benefit from additional simulated exposure to mitigate stress impacts on performance.
Middle Meningeal Artery Embolization for Primary Treatment of a Chronic Subdural Hematoma in a Pediatric Patient: A Systematic Review of the Literature and Case Report
Authors: Paro Mitch R. , Ollenschleger Martin D. , Fayad Mohamad F. , Bulsara Ketan R. , Stoltz Petronella , Martin Jonathan E. , Bookland Markus J. , Hersh David S. 
Published: December 2022

BACKGROUND:
Middle meningeal artery (MMA) embolization is becoming increasingly studied as a safe, effective treatment for chronic subdural hematoma (cSDH) in adults. Among pediatric patients, however, MMA embolization for cSDH has been rarely described, and the potential benefit of this approach for pediatric patients remains unknown.

OBJECTIVE:
To systematically review the literature and identify cases of pediatric MMA embolization for cSDH. We also report our experience with pediatric MMA embolization.

METHODS:
A systematic review of the literature was performed to identify cases of pediatric MMA embolization for cSDH. Inclusion criteria included English language availability and pediatric age defined as less than 18 years. A pediatric patient treated with MMA embolization was also identified at our institution.

RESULTS:
Five cases of pediatric MMA embolization for cSDH were identified in the literature. Two were associated with arachnoid cysts, 2 with antiplatelet/anticoagulation therapy, and 1 with abusive head trauma. There were no adverse events, and all patients demonstrated clinical and radiological improvement on follow-up. At our institution, a previously healthy 8-year-old male was found to have a right-sided acute-on-chronic SDH during a headache evaluation. A diagnostic angiogram was performed to rule out a dural arteriovenous fistula, and right-sided MMA embolization was performed concurrently. Rapid clinical and radiological improvement was observed, with complete resolution by 6 months.

CONCLUSION:
MMA embolization may represent a treatment option for pediatric patients with cSDH.
Outcome of Nerve Grafting for Radiation-Induced Brachial Plexopathy
Authors: Yin Yaobin , Xue Yunhao , Yang Baokai , Ng Chye Yew , Yang Chen , Li Feng , Li Wenjun , Li Bin , Wang Shufeng 
Published: December 2022

BACKGROUND:
There is no consensus on the optimal treatment for radiation-induced brachial plexopathy (RIBP).

OBJECTIVE:
To present our experience of using nerve resection and autografting as a treatment strategy for this challenging condition.

METHODS:
From September 2014 to January 2020, 8 patients with RIBP were treated with segmental nerve resection and autografting, with or without other supplementary procedures. All patients underwent sural nerve grafting to the musculocutaneous nerve. All were female with a mean age of 53 (range 38-64) years. Seven were on the left, and 1 was on the right. The mean follow-up duration was 33 (range 17-72) months.

RESULTS:
By the final review, 7 of 8 patients regained at least antigravity elbow flexion. Four patients reached Medical Research Council (MRC) grade 4, 3 MRC grade 3, and MRC grade 2 recovery in the biceps. The mean Visual Analog Score for pain improved from 2.6 preoperatively to 0.6 postoperatively (P = .042).

CONCLUSION:
Nerve resection and autografting may restore satisfactory elbow flexion in patients with RIBP.
Agroecology research in Europe: current status and perspectives
Authors: Iocola Ileana , Ciaccia Corrado , Colombo Luca , Grard Baptiste , Maurino Stefania , Wezel Alexander , Canali Stefano 
Published: December 2022

Background: Agroecology is increasingly seen as an important contribution for the development of more sustainable agriculture and food systems. Research can have a main role to support this path. Although it seems that there is a gradual increasing body of agroecology research, it clearly lacks good knowledge about this. The main objective of this study was therefore to map research projects related to agroecology in Europe with the aim to characterize European research in terms of implementation of agroecology elements, identify needs for the future cross collaboration between countries and networks, and support the setting up of appropriate research agendas fostering agroecology research in Europe. Methods: A desktop research with different databases related to European and transnational funding programmes was carried out to identify funded research projects involved in agroecology. The obtained projects were used to perform a social network analysis. Furthermore, two surveys were conducted, one with coordinators of identified projects and a second one for researchers engaged in agroecology. Results: Our study highlighted a predominant trajectory of agroecology research prone to the transformation of the agri-food system. France, Germany, Italy, Netherlands, Portugal, Spain, and United Kingdom were the most active countries engaged in agroecology research. In all surveys, issues related to efficiency improvement, synergies strengthening, local economy development, and co-creation and sharing of knowledge were the most implemented to support agri-food transformation. Transdisciplinary approaches were mainly addressed by European projects. Surveys reported a limited participation of value chain actors, while researchers, farmers, and their associations were the most involved. Survey respondents suggested to increase project duration and to introduce flexibility methods to modulate research actions according to the dynamic of the contexts. Conclusion: On the basis of the results, some policy recommendations were provided to fostering agroecology research in Europe and its contribution for transformation of agri-foods systems.
Improving Access to Rare Disease Treatments: Subsidy, Pricing, and Payment Schemes
Authors: Olsder Wendy , Martagan Tugce , Tang Christopher S. 
Published: December 2022

There are more than 7,000 known rare diseases, but pharmaceutical manufacturers developed treatments for only 500 of them. To improve the availability and accessibility of treatments for rare diseases, governments have introduced several programs including subsidies, exogenous pricing, and outcome-based payment schemes in recent years. What kind of subsidy programs and pricing mechanisms can improve patient access? Inspired by various pilot programs, we present a multistage game theoretic model to analyze different subsidy schemes proposed for rare diseases. In addition to the traditional setting in which the manufacturer sets the price, we consider an “exogenous pricing scheme” under which an independent consortium sets the price. We also examine an outcome-based payment scheme, which offers the drug for free if it is not efficacious. We formulate a four-stage Stackelberg game to determine whether it is optimal to subsidize the pharmaceutical manufacturer, the patients, or both. Our results offer several insights. First, we find that government subsidies are crucial to entice new drug development for rare diseases. Also, we find that the pricing scheme matters: The exogenous pricing scheme can improve patient welfare, but it reduces the manufacturer’s expected profit. We find that this result is robust even when an outcome-based payment scheme is used. This paper was accepted by Jayashankar Swaminathan, operations management. Funding: This work was supported by the Dutch Science Foundation [Nederlandse Organisatie voor Wetenschappelijk Onderzoek VENI Talent Scheme]. Supplemental Material: The data files and online appendices are available at https://doi.org/10.1287/mnsc.2022.4634 .
Hospice care delivery system requirements
Authors: Beiranvand Samira , Rassouli Maryam , Hazrati Maryam , Molavynejad Shahram , Hojjat Suzanne , Tuvesson Hanna , Zarea Kourosh 
Published: December 2022

Background:Hospice care is a perceived need in the Iranian health system.Aim:This qualitative study is explaining the stakeholders’ perception of what is required to develop a hospice care system for patients living with cancer in Iran.Methods:A total of 21 participants (specialists, policymakers, healthcare providers, cancer patients and family caregivers) were selected through purposeful sampling and interviewed in-depth in 2020. Interviews were analysed through directed content analysis.Findings:A total of 1054 codes, 7 categories and 21 subcategories were extracted. The requirements include the need to provide: multiple settings and diverse services; participatory decision making; integration into the health system; specialised human resources; an organised system of accountability; the preparation of the existing health system; and wider capacity-building in existing Iranian society.Conclusion:It is essential that Iranian services create a participatory comprehensive care plan, utilise expert manpower, integrate hospice care into the existing health system and organise a system of accountability. Policymakers should focus on the preparation of the health system and capacity building in society.
Impact of the input OSNR on data-driven optical fiber channel modeling
Authors: Ye Gao , Xiang Junjiang , Zhou Gai , Xiang Meng , Li Jianping , Qin Yuwen , Fu Songnian 
Published: December 2022

The data-driven approach is promising for computationally efficient modeling of optical fiber channels. Here, for the first time to our knowledge, we investigate the impact of the input optical signal-to-noise ratio (OSNR) on the accuracy of data-driven modeling for optical fiber channels, based on a conditional generative adversarial network (cGAN). Initially, considering a single span of 80 km of standard single mode fiber (SSMF), we vary the launched optical power for the ease of emulating both linear and nonlinear transmission scenarios. When the input OSNR of a root raised cosine (RRC)-shaped 16 quadrature amplitude modulation signal with a roll-off factor of 0.1 varies, we identify that there occurs an OSNR threshold for accurately modeling a single span of 80 km of SSMF in order to reach the normalized mean square error of less than 0.02 in relevance to the traditional split-step Fourier method. The OSNR thresholds are 19 dB and 21 dB, respectively, under scenarios of linear and nonlinear transmissions. Moreover, we verify that the OSNR threshold of accurate modeling is insensitive to both the modulation format and the RRC shaping of the input signal. Furthermore, we find that the cascaded use of cGAN well-trained for the single SSMF span is capable of modeling the multiple-span SSMF transmission in the case that the input OSNR threshold of 22.6 dB is satisfied. We believe that the identification of the OSNR threshold for data-driven optical fiber channel modeling is useful for the accurate and efficient emulation of long-haul fiber optical transmission.