bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of the concrete cover thickness ratio on the post-yield stiffness of bridge columns with partially unbonded unstressed steel strands
Authors: Ou Yu-Chen , Wu Jhen-Wei , Pratiwi Ade Yuniati 
Published: September 2022

AbstractA new self-centering concrete bridge column has been developed by the authors. The proposed bridge column uses unstressed partially unbonded seven-wire steel strands as elastic elements to reduce the residual displacement of the column after a strong earthquake. This research aimed to study the effect of concrete cover thickness ratio on the cyclic behavior of the proposed column. Four large-scale column specimens were tested using lateral cyclic loading. One column was the conventional concrete bridge column. The other three columns were the proposed self-centering bridge columns with varying concrete cover thickness ratios. Test results showed that partial unbonding effectively prevented the strands from yielding. The proposed columns showed post-yield stiffness ratios higher than the conventional column. The concrete cover thickness ratio did not significantly influence the hysteretic energy dissipation and the strain responses of longitudinal reinforcement. However, it had a significant impact on the post-yield stiffness ratio. The post-yield stiffness ratio of the proposed column tended to be inversely proportional to the concrete cover thickness ratio. A relationship was proposed between the concrete cover thickness ratio and the post-yield stiffness ratio for the preliminary design of the proposed column. Based on the relationship, the cover concrete thickness ratio should not exceed 5.1% to achieve a post-yield stiffness ratio of at least 5%, as recommended in the literature to control the residual displacement of a column.
Analysis of Delayed Surgery and Clinical Outcomes in Intermediate- and High-risk Papillary Thyroid Cancer
Authors: Zhou Huijun , Wu Jie , Shi Lei , Wang Yu , Liu Bin 
Published: September 2022

Abstract

Context
The optimal timing to performing thyroid surgery following a diagnosis of papillary thyroid cancer (PTC) has yet to be fully defined.

Objective
We aimed to examine if a delayed surgery may worsen the clinical outcome of PTC patients with intermediate- to high-risk of recurrence.

Methods
All consecutive PTC patients with intermediate- to high-risk of recurrence who underwent total thyroidectomy and radioactive iodine (RAI) ablation at 3 tertiary hospitals in southwest China were retrospectively included. Excellent response at 1-year follow-up after initial therapy was defined as no clinical, imaging, or biochemical evidence of PTC. Association of the timing of surgery and excellent response rates.

Results
The study included 871 patients. The median time interval between PTC diagnosis and surgery was 2 months (range, 1-87 months). Patients were divided according to the timing of surgery, &lt; 6 months (group A, 624/871 [71.6%]), ≥ 6 to 11 months (group B, 123/871 [14.1%]), or ≥ 12 months (group C, 124/871 [14.2%]). One year after initial therapy, 64.7%, 71.5%, and 66.1% of patients in groups A, B, and C, respectively, achieved excellent response (P = 0.27). The lack of impact of surgery timing was observed across intermediate- to high-risk classifications and all T stage categories. These findings did not change when we separately analyzed the groups according to RAI dose (intermediate-dose group: ≤ 3.7 GBq [n = 654], and high-activity group: 5.5 GBq [n = 217]) further subdivided according to the timing of surgery.

Conclusion
Timing of surgery does not seem to affect short-term disease outcomes in intermediate- to high-risk PTC patients. Further research is necessary to assess the impact of delayed surgery on long-term prognosis.
role of obstetricians and neonatologists in childcare in the time of the COVID-19 pandemic
Authors: Borowik Joanna , Kaziród Karolina , Brodowski Wojciech , Miturski Andrzej , Semczuk-Sikora Anna 
Published: September 2022

Introduction: The COVID-19 pandemic has caused numerous changes to the healthcare system, including care for the newborns.
Aim of the study: The aim of the study was to create a clear set of recommendations used in the care of a newborn during the SARS-CoV-2 pandemic.
State of knowledge: Despite the low risk of infection of the newborn in utero or during vaginal delivery, in rare cases there is a possibility of vertical transmission of the SARS-CoV-2 virus. Every newborn baby whose mother has been diagnosed with COVID-19 disease should be screened for infection. Suspected neonates should be isolated from healthy children and kept in quarantine until the test result is obtained. It is essential to constantly monitor your baby's health and be alert to any possible signs of infection. Medical personnel should ensure adequate protection when handling an infected newborn. A healthy infant whose mother is SARS-Cov-2 positive may be discharged home provided it is looked after by a healthy caregiver.
Summary: New patterns of management in maternity and neonatal departments are associated with changes that may have a significant impact on the mother-child relationship. When making decisions aimed at reducing the spread of SARS-CoV-2 infection, it is necessary to seek solutions taking into account the needs of this particular group of patients.
Socioenvironmental Pathways to Conservation of Natural Resources & Environmental Betterment
Authors: Squires Victor , Feng Haiying 
Published: September 2022

This is an analysis of past and on-going ‘land and people’ management issues in China’s extensive rural areas. Both authors draw on more than 20 years’ experience derived from working in China’s arid northwest and on the ‘roof of the world” on the Qinghai-Tibetan Plateau (QTP). Worldwide, communities of people have adapted to hot and dry, cold and arid and hot and humid environments. They have shown their adaptability and have made remarkable innovations that enabled them to survive for centuries. But many of the strategies used now, and those unaltered from the past, are inadequate to cope with the fast-changing situation in modern China. The paper is in several parts. We explain some of the terminology around socioenvironmental thinking and its application to the real world with examples from the Qinghai-Tibetan Plateau – a vast upland in NW China. An attempt is made to show how a better understanding of the interplay of fast and slow variables can help to ensure conservation (wise use) of natural resources and serve the needs of the land users (mainly semi-nomadic herders of yaks, goats, sheep, camels and horses). We suggest that the term ‘situation betterment’ is a more realistic goal and the ‘solving’ the manifold problems (ecological, legal, economic, political and logistic) that beset land users, administrators, policy makers and the law makers. An explanation of the systems approach and its relevance to socio-environmentalism is offered
A Novel Deep Learning ANN Supported on Langevin-Neelakanta Machine
Authors: De Groff Dolores , Neelakanta Perambur S. 
Published: September 2022

In the contexts of deep learning (DL) considered in artificial intelligence (AI) efforts, relevant machine learning (ML) algorithms adopted refer to using a class of deep artificial neural network (ANN) that supports a learning process exercised with an enormous set of input data (labeled and/or unlabeled) so to predict at the output details on accurate features of labeled data present in the input data set.
In the present study, a deep ANN is proposed thereof conceived with certain novel considerations: The proposed deep architecture consists of a large number of consequently placed structures of paired-layers. Each layer hosts identical number of neuronal units for computation and the neuronal units are massively interconnected across the entire network. Further, each paired-layer is independently subjected to unsupervised learning (USL). Hence, commencing from the input layer-pair, the excitatory (input) data supplied flows across the interconnected neurons of paired layers, terminating eventually at the final pair of layers, where the output is recovered. That is, the converged neuronal states at any given pair is iteratively passed on to the next pair and so on. The USL suite involves collectively gathering the details of neural information across a pair of the layers constituting the network. This summed data is then limited with a specific choice of a squashing (sigmoidal) function; and, the resulting scaled value is used to adjust the coefficients of interconnection weights seeking a convergence criterion. The associated learning rate on weight adjustment is uniquely designed to facilitate fast learning towards convergence. The unique aspects of deep learning proposed here refer to: (i) Deducing the learning coefficient with a compatible algorithm so as to realize a fast convergence; and, (ii) the adopted sigmoidal function in the USL loop conforms to the heuristics of the so-called Langevin-Neelakanta machine. The paper describes the proposed deep ANN architecture with necessary details on structural considerations, sigmoidal selection, prescribing required learning rate and operational (training and predictive phase) routines. Results are furnished to demonstrate the performance efficacy of the test ANN.
On the critical Choquard-Kirchhoff problem on the Heisenberg group
Authors: Sun Xueqi , Song Yueqiang , Liang Sihua 
Published: September 2022

Abstract
In this paper, we deal with the following critical Choquard-Kirchhoff problem on the Heisenberg group of the form:

M

(

‖
u

‖

2

)

(

−

Δ

H

u
+
V
(
ξ
)
u

)

=

∫

H

N

∣
u

(

η

)

∣

Q

λ

∗

∣

η

−
1

ξ

∣

λ

d
η

∣
u

∣

Q

λ

∗

−
2

u
+
μ
f

(

ξ
,
u

)

,

M\left(\Vert u{\Vert }^{2})\left(-{\Delta }_{{\mathbb{H}}}u\left+V\left(\xi )u)=\left(\mathop{\int }\limits_{{{\mathbb{H}}}^{N}}\frac{| u\left(\eta ){| }^{{Q}_{\lambda }^{\ast }}}{| {\eta }^{-1}\xi {| }^{\lambda }}{\rm{d}}\eta \right)| u{| }^{{Q}_{\lambda }^{\ast }-2}u+\mu f\left(\xi ,u),

where

M

M

is the Kirchhoff function,

Δ

H

{\Delta }_{{\mathbb{H}}}

is the Kohn Laplacian on the Heisenberg group

H

N

{{\mathbb{H}}}^{N}

,

f

f

is a Carathéodory function,

μ
>
0

\mu \gt 0

is a parameter and

Q

λ

∗

=

2
Q
−
λ

Q
−
2

{Q}_{\lambda }^{\ast }=\frac{2Q-\lambda }{Q-2}

is the critical exponent in the sense of Hardy-Littlewood-Sobolev inequality. We first establish a new version of the concentration-compactness principle for the Choquard equation on the Heisenberg group. Then, combining with the mountain pass theorem, we obtain the existence of nontrivial solutions to the aforementioned problem in the case of nondegenerate and degenerate cases.
A micro/nano joint satellite design of high maneuverability for space debris removal
Authors: An Yuan , Chen Dan , Tai Nengjian , Zhu Jun , Zhang Ge , Zhang Qi 
Published: September 2022

Abstract
Ever-increasing space debris poses a great threat to spacecraft safety; its removal debuts as an innovative technology and will be in demand in the future. This article proposes a design for micro/nano joint satellites composed of four micro/nanosatellites with high maneuverability to clear space debris. The design incorporates two operating modes with typical applications, and the joint satellite features and essential key technologies are introduced. With the aim to demonstrate well-performed image data fusion and processing of the design, four cameras with different spectral and optical properties are installed for each micro/nanosatellite to acquire images and spectral characteristics for multifeatured identification of debris based on comprehensive analysis. Due to the different remote sensing payloads of the four micro/nanosatellites, the joint satellite is also capable of remote sensing. Compared with a single micro/nanosatellite, the joint satellite is more accurate for debris identification and rapid on-orbit maneuverability in addition to the superior flexibility brought by a touch-and-unfold separating removal mechanism.
Effects of KCa channels on biological behavior of trophoblasts
Authors: Zhang Xiaolei , Yang Meitao , Lv Dan , Xie Yin , Sun Yanan , Zhang Yanling , He Mengzhou , Liu Haiyi , Li Fanfan , Deng Dongrui 
Published: September 2022

Abstract
The Ca2+-activated potassium (KCa) channels are involved in many cellular functions, but their roles in trophoblasts are unclear. This study aimed to clarify the effects of KCa channels on the biological behavior of trophoblasts. The localization and expression of the three types of KCa channels, including large-conductance KCa channels (BKCa), intermediate-conductance KCa channels (IKCa), and small-conductance KCa channels (SKCa), were detected in human chorionic villi taken from pregnant women between 5 and 8 weeks of gestation (n = 15) and HTR-8/SVneo cells. The effects of KCa channels on proliferation, apoptosis, and migration of HTR-8/SVneo cells were examined by using the activators or inhibitors of KCa channels. Results showed that KCa channels were mainly localized on the membrane and in the cytoplasm of trophoblasts in human chorionic villi and HTR-8/SVneo cells. The proliferation and migration of HTR-8/SVneo cells were inhibited by activating KCa channels. Apoptosis of trophoblasts was promoted through activating BKCa channels but was not affected by neither activating nor inhibiting IKCa and SKCa channels. This study substantiated the abovementioned biological roles of KCa channels in trophoblast cells, which is fundamental to further research on whether dysfunction of KCa channels is involved in the pathogenesis of pregnancy-related complications.
Approximate solution of linear integral equations by Taylor ordering method: Applied mathematical approach
Authors: Ghamkhar Madiha , Wajid Laiba , Shahzad Khurrem , Safdar Rabia , Alhazmi Sharifah E. , Lashin Maha M. A. , Jamshed Wasim , Eid Mohamed R. , Alkhatib Soliman 
Published: September 2022

Abstract
Since obtaining an analytic solution to some mathematical and physical problems is often very difficult, academics in recent years have focused their efforts on treating these problems using numerical methods. In science and engineering, systems of integral differential equations and their solutions are extremely important. The Taylor collocation method is described as a matrix approach for solving numerically Linear Differential Equations (LDE) by using truncated Taylor series. Integral equations are used to solve problems such as radiative transmission and the oscillation of a string, membrane, or axle. Differential equations can be used to tackle oscillating difficulties. To discover approximate solutions for linear systems of integral differential equations with variable coefficients in terms of Taylor polynomials, the collocation approach, which is offered for differential and integral equation solutions, will be developed. A system of LDE will be translated into matrix equations, and a new matrix equation will be generated in terms of the Taylor coefficients matrix by employing Taylor collocation points. The needed system will be converted to a linear algebraic equation system. Finding the Taylor coefficients will lead to the Taylor series technique.
Comparing Different HWTT Analysis Methods for Asphalt Mixes Containing RAP and Correlating with MIST-TSR
Authors: Showkat Burhan , Singh Dharamveer 
Published: September 2022

Abstract
The use of recycled asphalt pavement (RAP) is associated with economic and environmental benefits. There is a general consensus that RAP leads to an improvement in the rutting and moisture damage resistivity of asphalt mixes. The Hamburg wheel tracking test (HWTT) is adopted to ascertain these distresses and is gaining popularity in the asphalt community. However, there is no step-by-step procedure to analyze the results of HWTT in AASHTO T324, Standard Method of Test for Hamburg Wheel-Track Testing of Compacted Asphalt Mixtures. Hence, there has been a rapid increase in number of analysis methods. A comparative study of these analysis methods is needed. At the same time, the moisture-induced stress tester (MIST) has been recently developed to quickly simulate stripping due to repeated pore pressure generation. A correlation between tensile strength ratio after MIST conditioning (M-TSR) and HWTT is warranted. In this study, asphalt concrete grade 1 mix containing 0, 10, 20, 30, and 40 % RAP by weight was designed and subjected to HWTT, MIST conditioning (varying stress cycles of 0, 1,000, 2,000, 3,500, 5,000, and 10,000), and indirect tensile (IDT) strength test. HWTT results were analyzed using eight different analysis methods viz. Iowa Department of Transportation (DOT), Oklahoma DOT, Texas DOT, third order (cubic) model and curvature, Francken model, rutting index and area, three-stage deformation model, and three-stage Weibull method. Based on results, this study recommends the Texas DOT and rutting index and area method for analyzing HWTT results. M-TSR was found to have a good correlation with HWTT moisture damage parameters except the moisture damage parameter from rutting index and area method and three-stage deformation model method.
Intelligent Control of Microwave Heating Temperature for Smart City Road Deicer Considering Ambient Temperature
Authors: Guo Meili 
Published: September 2022

Abstract
Snow in winter can make roads into ice, thus hindering people’s normal life travel. Therefore, in order to realize the quick deicing of roads in winter, an intelligent control method of microwave heating temperature for road deicers is proposed. The intelligent control system of microwave heating temperature was designed by analyzing the influence of ambient temperature on deicing efficiency. In terms of hardware, the structure of the microwave circuit control system is constructed by using a microwave generation system to realize the heating of ice and the measurement of temperature. Simulation results show that the method has a good effect on temperature control and improves deicing efficiency.
The effectiveness of high-intensity interval training on body composition of rodent models of obesity: A systematic review and meta-analysis
Authors: Sordi Ana Flávia , Silva Bruno Ferrari , Furlan Julia Pedrosa , Moraes Solange Marta Franzói de , Guariglia Débora Alves , Peres Sidney Barnabé 
Published: September 2022

Abstract
The present systematic review was compiled to analyze the effectiveness of High-intensity interval training (HIIT) protocols on the body composition of rodents with obesity. Databases were searched until February 2021 for experimental trials in rodents with a minimum duration of four weeks of HIIT and endpoints associated with obesity. The data were analyzed by meta-analysis performed for comparisons of body composition. Sensitivity analysis was performed to investigate the consistency of individual researches. Of all of the 524 studies found, only 14 were included. The analysis showed a significant reduction in body weight ([CI 95%: –8.35; –1.98] P ≤ 0.01), adiposity index ([IC 95%: –1.04; –0.80] P ≤ 0.01), and fat pads ([IC 95%: –0.59; –0.06] P ≤ 0.01). HIIT performed on treadmill or water was effective to reduce body weight (P < 0.05). In conclusion, HIIT attenuated both body weight and adiposity induced either by HFD (high-fat diet) or by GOM (genetic obese model), thereby inducing positive changes in body composition.
Introduction of a pharmacological neurovascular uncoupling model in rats based on results of mice
Authors: Varga Bence Tamás , Gáspár Attila , Ernyey Aliz Judit , Hutka Barbara , Tajti Brigitta Tekla , Zádori Zoltán Sándor , Gyertyán István 
Published: September 2022

Abstract
Our aim was to establish a pharmacologically induced neurovascular uncoupling (NVU) method in rats as a model of human cognitive decline. Pharmacologically induced NVU with subsequent neurological and cognitive defects was described in mice, but not in rats so far.
We used 32 male Hannover Wistar rats. NVU was induced by intraperitoneal administration of a pharmacological “cocktail” consisting of N-(methylsulfonyl)-2-(2-propynyloxy)-benzenehexanamide (MSPPOH, a specific inhibitor of epoxyeicosatrienoic acid-producing epoxidases, 5 mg kg−1), L-NG-nitroarginine methyl ester (L-NAME, a nitric oxide synthase inhibitor, 10 mg kg−1) and indomethacin (a nonselective inhibitor of cyclooxygenases, 1 mg kg−1) and injected twice daily for 8 consecutive days.
Cognitive performance was tested in the Morris water-maze and fear-conditioning assays. We also monitored blood pressure. In a terminal operation a laser Doppler probe was used to detect changes in blood-flow (CBF) in the barrel cortex while the contralateral whisker pad was stimulated. Brain and small intestine tissue samples were collected post mortem and examined for prostaglandin E2 (PGE2) level.
Animals treated with the “cocktail” showed no impairment in their performance in any of the cognitive tasks. They had higher blood pressure and showed cca. 50% decrease in CBF. Intestinal bleeding and ulcers were found in some animals with significantly decreased levels of PGE2 in the brain and small intestine.
Although we could evoke NVU by the applied mixture of pharmacons, it also induced adverse side effects such as hypertension and intestinal malformations while the treatment did not cause cognitive impairment. Thus, further refinements are still required for the development of an applicable model.
Management of antibiotic allergy in children: a practical approach
Authors: Kitsos Nikolaos , Cassimos Dimitrios , Xinias Ioannis , Agakidis Charalampos , Mavroudi Antigoni 
Published: September 2022

Background: About 10% of children are declared as allergic to antibiotics, with beta(β)-lactams being the most common perpetrators. However, few of these are confirmed by allergy tests. This characteristic of being allergic follows a child well into adulthood, leading to alternative, usually more expensive broad-spectrum antibiotics, contributing to antibiotic resistance and increasing healthcare expenses.
Objective: This review presents a practical approach to managing pediatric patients with antibiotic hypersensitivity reactions.
Material and methods: We updated the guidelines on antibiotic allergy in children by conducting systematic literature research using the best available evidence from PubMed search by entering the keywords “antibiotic allergy” and “children.” The search output yielded 5165 citations.
Results: Management of antibiotic allergy depends on the culprit antibiotic, and it includes confirmation of the diagnosis and finding a safe alternative to the culprit antibiotic. In particular patients with a history indicative of penicillin allergy can be treated with cephalosporins as an alternative to penicillin, especially with third-generation cephalosporins, except for those with similar R1 side chains. In patients with a history of immediate-type reactions to cephalosporins who require treatment with cephalosporins or penicillin, skin tests with cephalosporin or penicillin with different side chains should be performed. If allergy to macrolides is suspected, challenge tests are currently the only reliable diagnostic tool. The best strategy for managing patients with sulfonamide hypersensitivity is an alternative antibiotic. The skin prick tests and intradermal tests are not recommended for diagnosis of quinolone allergy, as they can activate dermal mast cells leading to false-positive results. Quinolone challenge test is the most appropriate test for diagnosing quinolone hypersensitivity.
Conclusion: Although adverse drug reactions to antibiotics are frequently documented, immunologically mediated hypersensitivity is unusual. In the event of an reaction, an appropriate diagnostic workup is required to identify the drug’s causal role. It is critical to avoid “labeling” a child as allergic without first conducting a proper diagnostic workup.