bluuebunny/crossref_metadata_2025_split huggingface dataset:
Image‐Derived Metrics Quantifying Hemodynamic Instability Predicted Growth of Unruptured Intracranial Aneurysms
Authors: Yang Hong‐Ho , Sayre James , Dinh Huy , Nael Kambiz , Colby Geoffrey , Wang Anthony , Villablanca Pablo , Salamon Noriko , Chien Aichi 
Published: August 2022

Background
Although image‐derived predictors of intracranial aneurysm (IA) rupture have been well explored, current understanding of IA growth is limited. Pulsatility index (PI) and wall shear stress PI (WSSPI) are important metrics measuring temporal hemodynamic instability. However, they have not been investigated in IA growth research. The present study seeks to verify reliable predictors of IA growth with comparative analyses of several important morphological and hemodynamic metrics between stable and growing cases among a group of unruptured IAs.

Methods
Using 3‐dimensional images, vascular models of 16 stable and 20 growing cases were constructed and verified using geodesic techniques. With an overall mean follow‐up period of 25 months, cases exhibiting a ≥10% increase in diameter were considered growing. Patient‐specific, pulsatile simulations were performed, and hemodynamic calculations were computed at 5 important regions of each aneurysm (inflow artery, aneurysm neck, body, dome, and outflow artery). Index values were compared between growing and stable IAs using ANCOVA controlling for aneurysm diameter. Stepwise multiple logistic regression and receiver operation characteristic analyses were conducted to investigate predictive models of IA growth.

Results
Compared with stable IAs, growing IAs exhibited significantly higher intrasaccular PI, intrasaccular WSSPI, intrasaccular spatial flow rate deviation, and intrasaccular spatial wall shear stress deviation. Stepwise logistic regression analysis revealed a significant predictive model involving PI at aneurysm body, WSSPI at inflow artery, and WSSPI at aneurysm body.

Conclusions
Our results showed that high degrees of hemodynamic variation within IAs are linked to growth, even after controlling for morphological parameters. Furthermore, evaluation of PI in conjunction with WSSPI yielded a highly accurate predictive model of IA growth. On validation in future cohorts, these metrics may aid in early identification of IA growth and understanding of IA remodeling mechanisms.
Y‐Stent–Assisted Coiling of Wide‐Necked Intracranial Aneurysms With the Neuroform Atlas Stent System
Authors: Jadhav Ashutosh P. , Desai Shashvat M. , Jovin Tudor G. , Hanel Ricardo A. , Sauvageau Eric A. , Aghaebrahim Amin , Lin Eugene , Khaldi Ahmad , Gupta Rishi G. , Johnson Andrew K. , Frei Donald , Loy David , Malek Adel , Toth Gabor , Siddiqui Adnan , Reavey‐Cantwell John , Thomas Ajith , Hetts Steven W. , Zaidat Osama O. , Jankowitz Brian T. ,   for the ATLAS Investigators
Published: August 2022

Background
Endovascular management of wide‐necked bifurcation aneurysms poses a therapeutic challenge, as coiling often requires the use of multiple adjunctive stent constructs to achieve successful embolization without compromising parent vessel integrity. The Neuroform Atlas Stent System is a novel low‐profile, intraluminal remodeling device. The study aims to investigate the safety and efficacy of Y‐stent–assisted coiling configuration constructs using the next generation stent for aneurysm coil embolization.

Methods
Subjects undergoing Y‐stent–assisted coiling in the ATLAS IDE (Safety and Effectiveness of the Treatment of Wide Neck, Saccular Intracranial Aneurysms with the Neuroform Atlas Stent System Investigational Device Exception) trial were identified for subgroup analysis. Enrollment in the trial was not stratified on the basis of the procedural stenting technique used. The primary efficacy end point was complete aneurysm occlusion (Raymond–Roy class 1) on 12‐month angiography, in the absence of re‐treatment or parent artery stenosis (>50%) at the target location. The primary safety end point was any major stroke or ipsilateral stroke or neurological death within 12 months. Adjudication of the primary end points was performed by an independent imaging core laboratory and the clinical events committee.

Results
A total of 60 subjects were identified. The mean age was 59, and 28.3% were men. The median aneurysm size was 6.7 mm, with a median neck size of 4.3 mm. Frequently reported aneurysm locations included the basilar apex (56.7%), anterior communicating artery (20.0%), and middle cerebral artery bifurcation (11.7%). The composite primary efficacy end point was achieved in 81.1% of subjects. Overall, 1.7% of subjects experienced a primary safety endpoint of major ipsilateral stroke or neurological death.

Conclusion
In the ATLAS IDE aneurysm cohort premarket approval study, Y‐stent–assisted coiling with Neuroform demonstrated high rates of complete aneurysm occlusion at 12 months, with low rates of morbidity.
Implementation of FAIR Guidelines in Selected Non-Western
Geographies
Authors: Lin Yi , Purnama Jati Putu Hadi , Aktau Aliya , Ghardallou Mariem , Nodehi Sara , van Reisen Mirjam 
Published: August 2022

Abstract
This study provides an analysis of the implementation of FAIR Guidelines in selected non-Western geographies. The analysis was based on a systematic literature review to determine if the findability, accessibility, interoperability, and reusability of data is seen as an issue, if the adoption of the FAIR Guidelines is seen as a solution, and if the climate is conducive to the implementation of the FAIR Guidelines. The results show that the FAIR Guidelines have been discussed in most of the countries studied, which have identified data sharing and the reusability of research data as an issue (e.g., Kazakhstan, Russia, countries in the Middle East), and partially introduced in others (e.g., Indonesia). In Indonesia, a FAIR equivalent system has been introduced, although certain functions need to be added for data to be entirely FAIR. In Japan, both FAIR equivalent systems and FAIR-based systems have been adopted and created, and the acceptance of FAIR-based systems is recommended by the Government of Japan. In a number of African countries, the FAIR Guidelines are in the process of being implemented and the implementation of FAIR is well supported. In conclusion, a window of opportunity for implementing the FAIR Guidelines is open in most of the countries studied, however, more awareness needs to be raised about the benefits of FAIR in Russia and Kazakhstan to place it firmly on the policy agenda.
The Impact of COVID-19 and FAIR Data Innovation on Distance Education in Africa
Authors: Akindele Akinyinka Tosin , Arulogun Oladiran Tayo , Taye Getu Tadele , Amare Samson Yohannes , Van Reisen Mirjam , Berhe Kibrom Fekadu , Gusite Balyejusa 
Published: August 2022

Abstract
Prior to the advent of the COVID-19 pandemic, distance education, a mode of education that allows teaching and learning to occur beyond the walls of traditional classrooms using electronic media and online delivery practices, was not widely embraced as a credible alternative mode of delivering education, especially in Africa. In education, the pandemic, and the measures to contain it, created a need for virtual learning/teaching and showcased the potential of distance education. This article explores the potential of distance education with an emphasis on the role played by COVID-19, the technologies employed, and the benefits, as well as how data stewardship can enhance distance education. It also describes how distance education can make learning opportunities available to the less privileged, geographically displaced, dropouts, housewives, and even workers, enabling them to partake in education while being engaged in other productive aspects of life. A case study is provided on the Dutch Organisation for Internationalisation in Education (NUFFIC) Digital Innovation Skills Hub (DISH) project, which is implemented via distance education and targeted towards marginalised individuals such as refugees and displaced persons in Ethiopia, Somalia, and other conflict zones, aiming to provide them with critical and soft skills for remote work for financial remuneration. This case study shows that distance education is the way forward in education today, as it has the capability to reach millions of learners simultaneously, educating, lifting people out of poverty, and increasing productivity and yields, while ensuring that the world is a better place for future generations.
Classification and prediction of cognitive performance differences in older age based on brain network patterns using a machine learning approach
Authors: Krämer Camilla , Stumme Johanna , da Costa Campos Lucas , Rubbert Christian , Caspers Julian , Caspers Svenja , Jockwitz Christiane 
Published: August 2022

Abstract
Age-related cognitive decline varies greatly in healthy older adults, which may partly be explained by differences in the functional architecture of brain networks. Resting-state functional connectivity (RSFC) derived network parameters as widely used markers describing this architecture have even been successfully used to support diagnosis of neurodegenerative diseases. The current study aimed at examining whether these parameters may also be useful in classifying and predicting cognitive performance differences in the normally aging brain by using machine learning (ML). Classifiability and predictability of global and domain-specific cognitive performance differences from nodal and network-level RSFC strength measures were examined in healthy older adults from the 1000BRAINS study (age range: 55–85 years). ML performance was systematically evaluated across different analytic choices in a robust cross-validation scheme. Across these analyses, classification performance did not exceed 60% accuracy for global and domain-specific cognition. Prediction performance was equally low with high mean absolute errors (MAEs ≥ 0.75) and low to none explained variance (R2 ≤ 0.07) for different cognitive targets, feature sets, and pipeline configurations. Current results highlight limited potential of functional network parameters to serve as sole biomarker for cognitive aging and emphasize that predicting cognition from functional network patterns may be challenging.
What does Job Want? Desire, Fear, Anxiety, and God in and Beyond Job 23
Authors: Hankins Davis 
Published: August 2022

Abstract
Job expresses several distinct desires in the poetic portions of the book of Job. Many interpreters have analyzed how Job uses legal language to express a desire to contend with God in court, and Job 23 is often cited as exemplary of this wish. However, in ch. 23 and elsewhere, Job rejects this imaginary courtroom scene as an impossibility because he experiences God’s presence as debilitating to his constitution as a subject. Job subsequently expresses a different resolve that is rooted in his actual experiences, which he describes in ways that correspond to certain psychoanalytic accounts of anxiety. In ch. 23, Job resolves to speak his way into the divine darkness that envelopes and effaces him, and this reorientation to Job’s experience and desire permits a fresh understanding of what makes Job’s perspective different from and problematic for traditional wisdom, which the three friends articulate and represent. The friends counsel Job to assume a pious posture of fear, which is unavailable to him because of his experience of anxiety. The desire that Job ultimately expresses in ch. 23 finds an intriguing echo in Job’s final words in 42:2–5, and this casts new light on the events narrated in the book’s prose introduction and conclusion, which in turn permits a new perspective on the book of Job as a whole.
The Old and the Young in Luke-Acts: The Lukan Literary Efforts for the Post-War Trauma, Generational Unity, and the Empowerment of the Younger Generation
Authors: Kim Jin Young 
Published: August 2022

Abstract
While many scholars point out the effect of the Jewish War on the formation of early Christian identities, not many have analyzed the generational dynamic over this traumatic experience and how the New Testament authors address this issue through their literary efforts. In this article, by utilizing sociological discussions on intergenerational tensions and integration in post-war societies, I present a generational interpretation of the literary efforts in Luke-Acts. I explore how Luke addresses the different understandings of the Temple between the older and younger generations and the trauma of its destruction persisting in the diaspora assemblies of Christ-followers. I argue that Luke, by portraying the old and young in particular ways (ex. Mary-Zechariah; early apostles-Stephen; Saul), attempts to heal the communal trauma of the war, promote mutual understanding between generations, and empower the next generation for the survival of the ekklēsia.
Vocabulary-Based Classification and Contact-Induced Formation of Neologisms in Two Standard Varieties of Karelian
Authors: Tavi Susanna , Tavi Lauri 
Published: August 2022

Abstract
This paper investigates the lexical similarities and formation of neologisms of two written standard varieties of Karelian, North and Livvi Karelian, spoken in the Republic of Karelia, Russia. Firstly, a naïve Bayes statistical model was generated to classify North and Livvi Karelian newspaper texts automatically. Secondly, the word formation strategies of neologisms from the classified newspaper texts were studied. The strategies between the two varieties were compared in terms of the code-copying framework. The results from the automatic classification and the investigation of neologisms show that the standards differ in lexicon and phonology, but the strategies of forming neologisms are similar: the most common strategy is to form words by language-internal means, and the other strategies are selective and global copying from Finnish, Russian, and English. The similar strategies in both standards suggest similar language planning.
The Equilibrium Point Between the Autonomy of Parliament and Other Constitutional Principles, as Viewed Through The Theoretical Framework of a System of Constitutional Justice. Case-Study: Italy
Authors: Albanesi Enrico 
Published: August 2022

Abstract
Scholarly debate concerning the judicial review of parliamentary proceedings has mainly focused on the constitutional principles in the light of which such a review should be excluded/grounded/limited. However, the equilibrium point between these principles remains elusive. This essay does not attempt to resolve this issue, since appropriate solutions can differ greatly from one legal order to another. Moreover, this being a matter of balance, a solution cannot be given once and for all, even domestically.
Instead, this essay aims to enrich existing studies, suggesting a methodology for viewing (and critically analysing) the equilibrium point in a domestic setting. First, however, supranational/international ‘constitutional’ principles should also be considered. Some examples of case-law (mainly concerning Italy) will be given. Secondly, such a balance should be viewed within the theoretical framework of the specific system of constitutional justice established domestically (i.e. types of standards, acts to be reviewed, jurisdictional disputes, subjects that can initiate disputes, violations of the Constitution). The validity of this second approach is then proved as it relates to Italy.
Resolution of Non-performing Assets of Commercial Banks: The Evidence from Banker’s Perspective in Indian Banking Sector
Authors: Chawla Sonia , Rani Seema 
Published: August 2022

The present article draws on the banker’s perspective and extracts some practical insights about the factors behind specific NPAs resolution strategies. Based on the thorough review of the perspective, conceptual and empirical literature, and using exploratory factor analysis (EFA), the study has identified 21 dimensions for ‘management of NPAs’. The empirical analysis of these dimensions has extracted 7 factors for management to be significant. A structured questionnaire has been developed and data has been collected from officers in different banks in India, especially working in the credit department. The questionnaire has been empirically tested for reliability and validity using confirmatory factor analysis (CFA) and also Z-test for checking the significance of the explored and confirmed factors. The present research work offers pragmatic suggestions for banking regulators, on improving the asset quality of banks in India and also throws new insights on effective credit management in banks. JEL Codes: G01, G21, G32, E44
Effects of Different Sources of Low-Dose Caffeine on Mood/Arousal and Cognitive Performance
Authors: Irwin Christopher , McCartney Danielle , Grant Gary , Delang Nathan , Bartrim Karly , Cox Gregory R , Desbrow Ben 
Published: August 2022

In this study we investigated the effects of variously derived sources of low-dose caffeine on mood/arousal and cognitive performance. Twenty-two participants (15 men, 7 women; M age: 28.2, SD = 9.0 years) undertook five randomized, crossover trials in which they consumed either a water control (CON) or 80 mg of caffeine from one of four sources (coffee [COF], energy drink [END], capsule [CAP], and dissolvable mouth strip [STR]). We measured the participants’ perceived efficacy of these varied caffeine sources pre-treatment; and we measured mood/arousal at pre-treatment, and again at 15 and 45 minutes post-treatment. We also measured choice reaction-time at 15 and 45 minutes post-treatment, and participants completed the psychomotor vigilance task (PVT) 45 minutes post-treatment. Caffeine increased participant ratings of alertness and decreased their ratings of tiredness irrespective of source ( p’s < .05), and all sources of caffeine decreased reaction time on the PVT ( p’s < .05), with ex-Gaussian distributional analysis localizing this to the tau-parameter, indicating lower variability. However, only the COF source was associated with improved ‘overall mood’ ( p’s < .05). Participants expected to perform better on the PVT with COF compared to CON, but there were no other significant associations between source expectancy and performance. In sum, a modest dose of caffeine, regardless of source, positively impacted mood/arousal and cognitive performance, and these effects did not appear to be influenced by expectations.
The Italian McGill Quality of Life Questionnaire-Revised (MQoL-R): Psychometrics in Neurological and Neoplastic Populations
Authors: Aiello Edoardo Nicolò , Pain Debora , Radici Alice , Filippelli Elvira , Ruvolo Stefania , Madonia Francesca , Caimi Annarita , Sguazzin Cinzia 
Published: August 2022

Background The McGill Quality of Life Questionnaire-Revised (MQoL-R) is the gold standard for assessing QoL in end-of-life, chronic patients; however, an Italian standardization is lacking. Objective This study aimed at assessing the psychometric properties of the Italian MQoL-R in patients with chronic neurological/oncological conditions. Methods 177 inpatients with life-threatening, chronic neurological/oncological conditions were consecutively recruited in 8 clinics in Northern/Southern Italy were administered the MQoL-R and the Karnofsky Performance Status (KPS). Factorial structure (Confirmatory Factor Analysis, CFA), reliability (Cronbach's α) and construct validity against the KPS (Pearson's coefficients) were examined. Results The four-factor model (Physical, Psychological, Existential and Social subscales) was met (comparative fit index = .93; root mean square error of approximation = .07), with all items significantly loading on respective subscales. Internal consistency was good for both the whole scale (Cronbach's α = .83) and subscales ( range = .6-.85). The KPS was unrelated to MQoL-R measures, except for the Physical subscale ( r = .24). Conclusions The Italian MQoL-R is a valid and reliable tool to assess QoL in end-of-life, both neoplastic and neurological, chronic inpatients undergoing palliative care, whose adoption is thus encouraged in both clinical practice and research addressed to such populations.
A Single-Center Audit of BI-RADS 3 Assessment Category Utilization in Mammography and Breast Ultrasound
Authors: Common Jessica , Abdullah Peri , Alabousi Abdullah 
Published: August 2022

Purpose: To evaluate outcomes of breast lesions assessed at our institution as probably benign (Breast Imaging Reporting and Data System [BI-RADS] category 3) with an expected malignancy rate of less than or equal to 2 %. Methods: Average-risk women with a BI-RADS 3 assessment following mammographic and/or ultrasound evaluation at our institution between January 1 and December 31, 2017 were included. Cancer yield was calculated within 90 days and at 6-month intervals up to 36 months. Results: Among 517 women (median age, 52 years; range, 13–89 years) with a BI-RADS 3 assessment, 349 (67.5 %) underwent biopsy or completed follow-up imaging up to 36 months. One hundred and 68 (32.5 %) were lost to follow-up. Thirty of 349 (8.6 %) had their imaging upgraded and underwent biopsy, yielding six cancers (cancer yield, 6 of 349 women [1.7 %]). Among 569 lesions assessed as BI-RADS 3, 92 (16.2 %) were characterized by morphologic features other than those validated as probably benign in prospective clinical studies. Fifty three of 517 women (10.3 %) had follow-up beyond 24 months, and 24 (4.6 %) had follow-up beyond 36 months. Conclusion: Overall utilization of the BI-RADS 3 assessment category at our institution is appropriate with a 1.7 % cancer yield. However, the rate of loss to follow-up, percentage of non-validated findings assessed as probably benign, and redundancy in follow-up protocols are too high, and warrant intervention. A patient handout explaining the BI-RADS 3 assessment category and automatic scheduling of follow-up studies have been implemented at our center to address loss to follow-up.