bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immunogenicity of non-canonical HLA-I tumor ligands identified through proteogenomics
Authors: Lozano-Rabella Maria , Garcia-Garijo Andrea , Palomero Jara , Yuste-Estevanez Anna , Erhard Florian , Martín-Liberal Juan , de Olza Maria Ochoa , Matos Ignacio , Gartner Jared J. , Ghosh Michael , Canals Francesc , Vidal August , Piulats Josep Maria , Matias-Guiu Xavier , Braña Irene , Muñoz-Couselo Eva , Garralda Elena , Schlosser Andreas , Gros Alena 
Published: November 2022

AbstractTumor antigens are central to antitumor immunity. Recent evidence suggests that peptides from non-canonical (nonC) aberrantly translated proteins can be presented on HLA-I by tumor cells. Here, we investigated the immunogenicity of nonC tumor HLA-I ligands (nonC-TL) to better understand their contribution to cancer immunosurveillance and their therapeutic applicability. Using proteogenomics, we identified 517 nonC-TL from 9 patients with melanoma, gynecological, and head and neck cancer. We found no recognition of the 507 nonC-TL tested by autologousex vivoexpanded tumor reactive T-cell cultures while the same cultures demonstrated reactivity to mutated, cancer-germline, or melanocyte differentiation antigens. However,in vitrosensitization of donor peripheral blood lymphocytes against 170 selected nonC-TL, led to the identification of T-cell receptors (TCRs) specific to three nonC-TL, two of which mapped to the 5’ UTR regions of HOXC13 and ZKSCAN1, and one mapping to a non-coding spliced variant of C5orf22C. T cells targeting these nonC-TL recognized cancer cell lines naturally presenting their corresponding antigens. Expression of the three immunogenic nonC-TL was shared across tumor types and barely or not detected in normal cells. Our findings predict a limited contribution of nonC-TL to cancer immunosurveillance but demonstrate they may be attractive novel targets for widely applicable immunotherapies.
Biomechanics of Finger Pad Response under Torsion
Authors: de Dunilac Sophie du Bois , Bulens David Córdova , Lefèvre Philippe , Redmond Stephen J. , Delhaye Benoit P. 
Published: November 2022

AbstractSurface skin deformation of the finger pad during partial slippage at finger-object interfaces elicits tactile feedback. During object manipulation, torque is often present, which can cause partial slippage. Until now, studies of surface skin deformation have used stimuli sliding on rectilinear tangential trajectories.Here we studied surface skin dynamics under torsion. A custom robotic platform stimulated the finger pad with a flat transparent surface, controlling the normal forces and rotation speeds applied while monitoring the contact interface using optical imaging.We observed the characteristic pattern by which partial slips develop, starting at the periphery of the contact and propagating towards its centre, and the resulting surface strains. The 20-fold range of normal forces and angular velocities used highlights the effect of those parameters on the resulting torque and skin strains. While normal force increases the contact area, generated torque, strains, and twist angle required to reach full slip, angular velocity increases loss of contact at the periphery and strain rates (although not total strains). We also discuss the surprisingly large inter-individual variability in skin biomechanics, notably observed in the twist angle the stimulus needed to rotate before reaching full slip.
Choice of friction coefficient deeply affects tissue behaviour in epithelial vertex models
Authors: Guerrero Pilar , Perez-Carrasco Ruben 
Published: November 2022

ABSTRACTTo understand the mechanisms that coordinate the formation of biological tissues, the use of numerical implementations is necessary. The complexity of such models involves many assumptions and parameter choices that result in unpredictable consequences, obstructing the comparison with experimental data. Here we focus on vertex models, a family of spatial models used extensively to simulate the dynamics of epithelial tissues. Usually, in the literature, the choice of the friction coefficient is not addressed using quasi-static deformation arguments that generally do not apply to realistic scenarios. In this manuscript, we discuss the role that the choice of friction coefficient has on the relaxation times and consequently in the conditions of cell cycle progression and division. We explore the effects that these changes have on the morphology, growth rate, and topological transitions of the tissue dynamics. These results provide a deeper understanding of the role that an accurate mechanical description plays in the use of vertex models as inference tools.
Lean and agile supply chain strategies: the role of mature and emerging information technologies
Authors: Oliveira-Dias Diessica de , Maqueira Marín Juan Manuel , Moyano-Fuentes José 
Published: November 2022

PurposeThe significant changes that supply chains (SCs) are undergoing and the emergence of disruptive technologies have led to a growing effort to integrate novel and mature technologies into existing SC strategies. Thus, this study investigates the relationships between mature information technologies (ITs), emerging IT and the lean supply chain (LSC) and agile supply chain (ASC) strategies.Design/methodology/approachAn empirical study based on structural equation modeling of survey data from 256 Spanish focal companies has been conducted to test six hypotheses.FindingsDrawing on resource orchestration, our results point to mature IT use being an enabler of both LSC and ASC strategy implementation. The results also show an LSC mediating effect on the relationship between mature IT and ASC when SCs follow both strategies. Also, the implementation of emerging IT requires a process of consolidation over time to be genuinely useful as a facilitating mechanism for developing both the lean and agile strategies along the SC. In this sense, a suitable mix needs to be orchestrated between emerging and mature IT.Originality/valueThis study sheds light on the relevance of the mature IT and emerging IT in the context of two SC strategies (lean/agile) and provides practical and theoretical implications.
Explaining job satisfaction through the use of work–familybenefits and their impact on the employee’s family context
Authors: Gutiérrez Vargas Liliana María , Alegre Joaquin , Pasamar Susana 
Published: November 2022

PurposeThis study analyses the relationship between the use of work–family benefits and job satisfaction (JS). Furthermore, it proposes that work-to-family conflict (WFC) and work-to-family enrichment (WFE) play a mediating role in this relationship. The purpose of this paper is to address these issues.Design/methodology/approachData are gathered from 1,051 employees of Colombian organisations. Partial least squares path modelling is used.FindingsThe results show that the perception of WFE to a greater extent and the WFC perception, to a lesser extent, are significant mediators in the relationship between the use of benefits and JS.Practical implicationsThis study justifies investments and initiatives on the adoption and promotion of work–family benefits. Moreover, it provides practical clues on how to boost JS: WFC and WFE are variables to be considered.Originality/valueThis study proposes a multiple mediation model to analyse the relationship between the actual use of work–family benefits and JS from a family perspective. It contributes to the literature in examining antecedents of JS, highlighting the role of WFE.
Sport sponsorship as a booster for customer engagement: the role of activation, authenticity and attitude
Authors: Schönberner Jan , Woratschek Herbert 
Published: November 2022

PurposeIn marketing research, it is widely acknowledged that customer engagement leads to higher reputation, lower costs and increased revenues for firms. However, there are still open questions on how sport sponsorship can drive customer engagement. It is hypothesized that sponsors' activations correlate with customer engagement toward the sponsor. Specifically, the roles of sponsorship authenticity and attitudes toward the sponsor have received little attention in this context. Accordingly, this study aims to test the effects of sponsors' activations on customer engagement disposition (CED) and customer engagement behavior (CEB) by considering the roles of sponsorship authenticity and attitudes toward the sponsor.Design/methodology/approachAn online experiment with a factorial between-subjects design with 529 total participants was conducted. Data were analyzed through analysis of covariance (ANCOVA) and binary regression analysis.FindingsSponsors' activations can lead to positive or negative CEB, depending on how sport consumers evaluate the activation. Sponsorship authenticity reduces or enhances CEB following a sponsor's activation. Moreover, consumers' prior attitudes toward the sponsor influence the relationship between sponsors' activations and CED. The findings further showed that CED leads to CEB.Originality/valueThis research contributes to the sport sponsorship literature by empirically proving that sponsors' activations increase customer engagement toward the sponsors. Moreover, this is the first study testing consequences of sponsors' activations in relation to sponsorship authenticity and consumers' attitudes. Furthermore, the authors enrich the customer engagement literature by discussing the sponsors' activations as a marketing strategy to increase customer engagement and consequently firms' performance.
How enabling and coercive control systems influence individuals’ behaviors? Analysis under the lens of construal level theory
Authors: Santos Vanderlei dos , Beuren Ilse Maria 
Published: November 2022

Purpose
This stud aims to analyze the influence that the enabling and coercive management control systems (MCS) have on the individuals’ mental representations and their commitment to goals, satisfaction with the system and perceived organizational support. Under the lens of the construal level theory (CLT), it is assumed that: individuals exhibit more positive behaviors when the MCS is enabling rather than coercive; the effects of MCS on the behavior of individuals are explained by the way they mentally represent events; and these effects are intensified or mitigated according to the psychological distance.

Design/methodology/approach
The predictions were tested in an experiment with 131 undergraduate students, assuming a company that decides to implement a performance measurement system.

Findings
The results show that enabling MCS are interpreted more abstractly (high level of construction) and coercive MCS are represented more concretely (low level of construction). Furthermore, enabling systems lead to more positive behaviors (commitment to goals and perceived organizational support) than coercive ones, however, the satisfaction with the MCS is affected by both depending on psychological distance.

Originality/value
The CLT allowed broadening the understanding of the effects of enabling and coercive controls on individuals’ behavior, by assuming that mental representation can explain individuals’ behaviors. To the best of the authors’ knowledge, this study is the first to point out that temporal distance can attenuate the negative effects of coercive MCS on satisfaction with the system.
Shaping circular economy in the built environment in Africa. A bibliometric analysis
Authors: Mhlanga Jacob , Haupt Theodore C. , Loggia Claudia 
Published: November 2022

Purpose
This paper aims to explore the intellectual structure shaping the circular economy (CE) discourse within the built environment in Africa.

Design/methodology/approach
The study adopted a bibliometric analysis approach to explore the intellectual structure of CE in the built environment in Africa. The authors collected 31 papers published between 2005 and 2021 from the Scopus database and used VOSviewer for data analysis.

Findings
The findings show that there are six clusters shaping the intellectual structure: demolition, material recovery and reuse; waste as a resource; cellulose and agro-based materials; resilience and low-carbon footprint; recycling materials; and the fourth industrial revolution. The two most cited scholars had three publications each, while the top journal was Resources, Conservation and Recycling. The dominant concepts included CE, sustainability, alternative materials, waste management, lifecycle, demolition and climate change. The study concludes that there is low CE research output in Africa, which implies that the concept is either novel or facing resistance.

Research limitations/implications
The data were drawn from one database, Scopus; hence, adoption of alternative databases such as Web of Science, Google Scholar and Dimensions could potentially have yielded a higher number of articles for analysis which potentially would result in different conclusions on the subject understudy.

Originality/value
This study made a significant contribution by articulating the CE intellectual structure in the built environment, identified prominent scholars and academic platforms responsible for promoting circularity in Africa.
The formation and preservation of behavioral integration in the top management team of The Church of Jesus Christ of Latter-day Saints
Authors: Mendenhall Mark E. , Butler Frank C. , Roundy Philip T. , Ehat Andrew F. 
Published: November 2022

PurposeThis paper aims to study the formation and preservation of behavioral integration (BI) in the top management team (TMT) of The Church of Jesus Christ of Latter-day Saints from 1844 to the present.Design/methodology/approachAn analytically structured history approach within a case exemplar framework is adopted. Theoretical insights are extrapolated from the case study to form a process model of BI formation and preservation in TMTs.FindingsThe findings reveal that three factors primarily influence BI creation (induction, education and cementation) and that BI is preserved via an iterative process that is driven by CEO conservatorship, intentional mentoring and social modeling.Originality/valueThis study investigates an unexplored area in upper echelons theory: the process by which BI is formed and preserved in TMTs and presents a process model of BI formation and preservation that shifts attention in the literature from analyses of the effect of BI on various organizational outcomes to how it can be formed in the first place and then preserved.
Links between reading acquisition level, emotional difficulties and academic performance in school-aged children
Authors: Ihbour Said , Essaidi Oumaima , Laaroussi Meriem , Najimi Mohamed , Chigr Fatiha 
Published: November 2022

Purpose
This study aims to examine the associations between reading difficulties, anxiety and depressive symptoms, self-esteem status and academic achievement among children of school age in the Moroccan context.

Design/methodology/approach
This cross-sectional study was carried out on 302 Moroccan students aged 9 to 16 years, the latter having voluntarily participated in the different stages of the proposed assessments. Standardized reading tests administered individually allowed us to classify participants into three groups (good readers, intermediate level and weak readers). The subjects completed the measurements of three self-evaluative scales: the Beck depression inventory, the Coopersmith scale of self-esteem and the Taylor questionnaire of manifest anxiety. The variable of academic achievement is constituted by calculating the grade point averages of the last three semesters.

Findings
Emotional disturbances are more frequent in the “weak readers” and the “intermediate level” group when compared to the good readers. Academic achievement and reading level are negatively correlated with anxious-depressive symptoms and positively with self-esteem at each reading level; the analysis of the results does not show any relevant difference in terms of the psychopathological disorder intensity between girls and boys.

Research limitations/implications
This study emphasizes improving education and psychological support for learners. It also encourages the strengthening of strategies for dealing with learning disabilities and the emotional distress associated with them.

Practical implications
The trend toward an inclusive school and the recruitment of school psychologists is advantages to be considered in the Moroccan educational system.

Originality/value
In addition to psychopathological vulnerability and academic failure, the social and family dimensions of self-esteem are impaired in weak readers.
Consumer response to celebrity transgression: investigating the effects of celebrity gender and past transgressive and philanthropic behaviors using real celebrities
Authors: Rifon Nora J. , Jiang Mengtian , Wu Shuang 
Published: November 2022

Purpose
This study aims to develop and test a new research model of consumer response to celebrity transgression. It examines the effects of celebrity past transgression and philanthropic histories in influencing consumer acceptance (i.e. forgiveness and blame) of a single celebrity transgression behavior and the subsequent endorsement potential of the transgressed celebrity. It also examines consumer acceptance of celebrity transgressions from the gender perspective.

Design/methodology/approach
By using real celebrities, this study conducted a 2 (transgression history: high vs low) × 2 (philanthropic history: high vs low) × 2 (celebrity gender: male vs female) between-subject online experiment with 823 US young adults.

Findings
Results showed that forgiving (blaming) the transgressed celebrity was positively (negatively) associated with the celebrity’s endorsement potential. Transgression history had a significantly negative indirect effect on endorsement potential via its negative effect on forgiveness and positive effect on blame. Philanthropic history mitigated the negative indirect effect of transgression history on endorsement potential only for male celebrities, not female celebrities.

Originality/value
This study contributes to the current human brand and celebrity transgression literature and fills the research gap by using real male and female celebrities to incorporate the real history of celebrities as determinants of consumer judgment of celebrity transgression. This study also makes its unique contributions by focusing on the celebrity-related outcomes and demonstrating the moderating roles of past philanthropic behaviors and celebrity gender for their potential to mitigate the negative effects of transgression history on consumer responses to a single transgression.
How can innovation district performance be assessed? Insights from South East Queensland, Australia
Authors: Adu McVie Rosemary Sokalamis , Yigitcanlar Tan , Erol Isil , Xia Bo 
Published: November 2022

Purpose
Many cities across the world are actively investing in ways to excel in the innovation economy through the development of innovation districts as one of the most popular policy options. While innovation districts are among the leading drivers of innovation activities in cities, they are also high-cost and high-risk investments. Besides, holistic approaches for assessing these districts’ multifaceted performances are scarce. Bridging this knowledge gap is critical, hence, this paper aims to explore how innovation district performance can be assessed through a classification framework.

Design/methodology/approach
The paper introduces a multidimensional innovation district classification framework and applies it into Australian innovation districts with divergent features, functions, spatial and contextual characteristics. The study places 30 innovation districts from South East Queensland under the microscope of the framework to assess the multifaceted nature of innovation district performance. It uses qualitative analysis method to analyse both the primary and secondary data, and descriptive analysis with basic excel spreadsheet calculations to analyse the validity of the data.

Findings
The data analysis clusters 30 innovation districts from South East Queensland under three performance levels – i.e. desired, acceptable and unsavoury – concerning their form, feature and function characteristics.

Originality/value
The results disclose that the framework is a practical tool for informing planners, developers and managers on innovation district performances, and it has the capability to provide guidance for policymakers on their policy and investment decisions regarding the most suitable innovation district types and characteristics to consider.
The role of information for the customer journey in mobile food ordering apps
Authors: Rita Paulo , Eiriz Vasco , Conde Beatriz 
Published: November 2022

Purpose
This study aims to determine how to influence the customer journey of mobile food ordering applications (MFOAs) users. It researches how available information could influence customers’ intention to use MFOAs platforms in the prepurchase stage and explores the potential of personalized information to improve customer satisfaction with these services in the postpurchase stage.

Design/methodology/approach
This research followed a mixed design, combining qualitative (focus groups) and quantitative (online survey) research and using both content analysis and partial least squares structural equation modeling.

Findings
Two types of available information (firm-generated information and online customer reviews) had a positive influence on the behavioral intention to use MFOAs. Additionally, findings showed that different web personalization strategies, namely, content personalization, functional personalization and system-driven personalization, were useful tools to create customer satisfaction with this type of platform.

Research limitations/implications
The study discusses limitations regarding the sample and sampling process, indicator variables and measures.

Practical implications
The present research provides actionable insights for online food delivery providers.

Originality/value
This study addresses a research gap in the literature and provides a novel and richer understanding of customer behavior toward mobile food delivery platforms. Also, it adds to the personalization research by identifying and testing a range of web personalization strategies.
When individual action requires collective approval: a roadmap for solar power adoption by strata property owners
Authors: Charters Ben , Heffernan Troy , Daly Matthew 
Published: November 2022

Purpose
This paper aims to examine a situation in which individual action requires collective approval – solar power adoption in strata properties – and offers a motivation-opportunity-ability theory-based model with which such a situation may be approached.

Design/methodology/approach
A Delphi methodology was undertaken for this study, with three iterative questionnaires administered online to a panel of strata property, renewable energy and sustainable housing experts.

Findings
The Delphi panel’s insights have informed a new conceptual model, the Strata Solar Champion Roadmap (SSCR), outlining the variables affecting strata-based solar power adoption.

Research limitations/implications
Researchers and practitioners are encouraged to test and enhance the model’s generalisability. Further case studies or quantitative analysis measuring the strength of the relationships identified in the SSCR model is particularly necessary. The SSCR could also be applied when examining other common strata governance disputes.

Practical implications
Policymakers and social marketers are encouraged to apply the SSCR when planning interventions to facilitate strata scheme solar power adoption. Furthermore, the SSCR offers guidance to strata property owners and strata schemes seeking to adopt solar power, thus increasing renewable energy use in a major sector of the Australian energy market.

Originality/value
Within this context, the SSCR’s conceptualisation of strata-based solar PV adoption provides new insights into individual behaviour change requiring collective approval.