bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge, Attitude and Practices of the General Population towards COVID-19 Vaccinations: A Cross-sectional Study
Authors: Abbasi Hira , Ahmed Fareena Khalil , Muzamil Muhammad , Hussain Zaheer , Lal Abhishek 
Published: January 2022

Aims: This study aims to evaluate the knowledge, attitude, and practices of the general population towards coronavirus vaccinations in Pakistan.
Study Design: A cross-sectional study.
Place and Duration of Study: Sample: Department of Dental Surgery, Altamash Institute of Dental Medicine, Pakistan, between March 2021 and June 2021.
Methodology: A cross-sectional study was carried out among 500 individuals who were above 18 years of age. A well-constructed questionnaire consisting of 4 parts (Demographics, Knowledge, Attitude, and Practices) was constructed containing informed consent and distributed online. Spearman correlation test was used to analyse knowledge, attitude, and practices towards coronavirus vaccinations.
Results: A total of 500 responses were collected from the participants. Most of the participants had adequate knowledge regarding the availability of the vaccines. About 116 (23.2%) participants had contracted the virus. The majority of 308 (61.7%) participants agreed on vaccines to be effective against the virus. Most of the 401 (80.4%) participants were willing to get themselves vaccinated when their turn comes. 265 out of 500 (53.1%) people have been vaccinated against coronavirus. The minority of people assumed a chip inside the vaccine and religious factors as reasons not to get vaccinated. Those residing in urban locations and with increasing age had better knowledge and attitudes towards vaccinations.
Conclusion: To control and contain the ongoing pandemic, vaccination against the coronavirus is a must. There is still scope in evaluating and improving the general population’s knowledge regarding the vaccination programs especially in the rural areas where resources and socioeconomic status is weaker.
Psychological Stress Due to Covid-19 on Pregnant Women in Post Partal Period
Authors: Patel Abhi , Chakole Swarupa , Bhatt Neha 
Published: January 2022

There is no indication that covid-19 has a long-term effect on pregnancy, the mother's psychiatric condition, or the infant's developmental delay. Between May 1st and July 31st 2020, 72 pregnant patients with covid-19 took part in a study that took place in different locations. Since giving birth these woman patients engaged in three-month follow-up surveys. The data was collected from Covid-19 medical history, maternal reports, quarantine questionnaires, mother-baby feeding separation, and assessing the mothers psychiatric illnesses.
While there is no conclusive evidence of vertical transmission of SARS-COV-2, in order to reduce the risk of infection, healthcare professionals and researchers must focus more on the mental health of pregnant women, infant feeding, and closeness to the parents. This will aid in the early development of the new born, reducing stress on the mother.
COVID-19 Pandemic Impact on Emergency Department Visits and Quality of Service: A Comparative Cross-Sectional Study in a Tertiary Centre
Authors: Jaboua Maram Mohammed , Abdulhaq Warif Jameel , Almuntashiri Nada Saeed , Almohammdi Sarah Saud , Aldajani Asayel Qeblan , Alghamdi Ahmed Mohammed , Alsubhi Amjad Suda , Almehmadi Rahaf Ali 
Published: January 2022

Background: The COVID-19 pandemic has contributed to a devastating impact on emergency departments worldwide, resulting in a global crisis with various health consequences. We aimed to evaluate this impact on an emergency department (ED) visit of critical conditions such as Acute Coronary Syndrome (ACS), Cerebrovascular accident (CVA), Sepsis and Febrile neutropenia (FN), and to assess the quality of the ED after new adaptive measures were applied.
Methods: This is a comparative cross-sectional study to assess the number of patients who presented to the ED of King Abdullah Medical city with the specified diagnosis. We collected data via the E-medical records. We compared the data over three periods pre-lockdown, lockdown and post lockdown in years 2019-2021. For quality measurement, Adaa (Ministry of Health's program) was used to calculate the percentage of patients who stayed 4 hours or less in the ED.
Results: The total number of ED visits in the specified periods of study was 8387. The total numbers of patients for 2019, 2020, and 2020 respectively were 2011 (, ACS 70.4%, CVA 16.3%, sepsis and FN 13.3%.), 2733 (ACS 73.1%, CVA 9.9%, sepsis and FN 17.0%), and 3643 (ACS 64.0%, CVA 19.4%, sepsis and FN 16.7). The average percentage of patients who stayed 4 hours or less in the ED was 60% and 57.5% for 2020 and 2021, respectively.
Conclusion: Although we expected reductions in ED visits during COVID-19 periods, we found that visits were rising through the years 2019-2021.
The Use of Fluorometholone Eye Drops in a Public Healthcare Organization in Riyadh Province
Authors: Ahmad Nehad J. , Salkini Mohamad Ayman 
Published: January 2022

Aim: This study aimed to describe the use of fluorometholone eye drops in a public healthcare organization in Riyadh Province
Methodology: This is a retrospective study that includes reviewing the electronic prescriptions of fluorometholone eye drops among outpatients in a public healthcare organization in Riyadh Province
Results: During the study period, only 42 patients received fluorometholone eye drops. More than 64% of them were females and the age of 28.57% of them was between 20 and 29 years. More than 73% of the patients received fluorometholone eye drops for 1 week. Most of the prescriptions were prescribed by residents. More than 95% of the prescriptions were written by ophthalmology department.
Conclusion: The present study showed that fluorometholone eye drops was uncommonly prescribed in Al-Kharj. More studies are needed to describe the frequency of using and the pattern of prescribing fluorometholone eye drops.
Relationship between Dental Arch Width and Vertical Facial Morphology in Untreated Adults- A Retrospective Study
Authors: Narkhede Sameer , Sabharwal Kretikka , Soni Vivek , Shetty Karthick , Sonawane Sushma , Gadhiya Nitin , Singh Rakesh , Khamatkar Aparna , Sawant Veera 
Published: January 2022

Early orthodontic research has focused on the link between face shape and malocclusion. Orthodontic treatment's effectiveness and stability are heavily influenced by a patient's dental and facial anatomy. An orthodontist's knowledge of arch shapes is essential since it affects the patient's treatment and future growth.
For this study, the researchers wanted to see if there was a link between vertical face morphology and arch width, and if there was a difference in arch width between males and females. Arch width measurements (in millimetres) were utilised to determine the association.
For both males and females, participants with the lowest mandibular plane angle had the widest arch, followed by those with the average mandibular angle and those with the highest.
Anaesthetic Management of Left Temporal Glioma Undergoing Awake Craniotomy
Authors: Nisal Roshan , Kumar Vasam Rajesh , Pandit Wankhade Prachi , Ninave Sanjot 
Published: January 2022

For an awake craniotomy, a 49 year old (ASA 2), 78 kg woman with type II DM was given regional anaesthesia (scalp block) with monitored anaesthesia care (MAC). She had a headache, which was primarily caused by a left temporal glioma. She was very apprehensive about having this procedure done while she was awake. Fentanyl and Dexmedetomidine infusions in combination with scalp block initially provided adequate operating conditions. Because the patient needed to be fully awake, alert and cooperative during the language and motor mapping, all sedation was turned off. Patient was cooperative and obeyed commands during motor and language mapping as well as during tumour excision. Patient underwent complete excision of tumour without any postoperative neurological deficit. The success of the awake craniotomy is dependent on the patient cooperation, anaesthesiologist's experience, adequate intraoperative analgesia coverage, careful sedation titration, and meticulous planning.
Evaluation of the Relationship of Various Patterns of Quid Usage in Patients with Oral Submucous Fibrosis and Leukoplakia in Central India Population: A Cross Sectional Study
Authors: Chandak Rakhi , Chandak Manoj , Bansod Runal , Sathawane Ramhari , Bansod Rutuz , Thakre Pranali 
Published: January 2022

Background: Oral habits can cause severe oral potentially malignant disorders. There is a need to deeply analyse the role of betel nut in the causation of these disorders. Patients must be educated in order to prevent them from grabbing these conditions as inspection leads to prevention.
Aim: The aim of our study was to study and analyse the different patterns of quid usage among the participants with oral submucous fibrosis and leukoplakia in Central India population.
Patients and Methods: The study was performed on 90 patients amongst which 45 patients were clinically diagnosed of oral submucous fibrosis & the other 45 patients were diagnosed of leukoplakia. The cases were then subjected to a detailed questionnaire which aimed to extract information regarding the various types of quid usage habits, their frequency and duration. The data was recorded and statistical analysis was done.
Results: The study included 90 subjects – 86 males & 4 females. Out of 6 types of quid habits it is found that type IV (processed areca nut), Type VI (combined quid usage) quid caused OSMF stage II, Stage III & homogenous leukoplakia respectively. There is a strong association between duration and frequency of habit in causation of OSMF & leukoplakia.
Conclusion: The present study showed increased prevalence of OSMF & leukoplakia with type IV & VI quid usage among the population of Central India.
Effect of Muscle Energy Technique in Patient with Chronic Neck Pain- A Case Report
Authors: Jain Deepak , Patil Deepali , Phansopkar Pratik 
Published: January 2022

Introduction: Chronic neck pain might lead to a change in muscle tissue fibres. Neck discomfort is a serious and prevalent sickness. It is common in the general population, and it frequently results in severe impairment. These alterations have an impact on the cervical spine's capacity to govern 3-D movement efficiently. A range of manual therapy approaches are available to assist relieve pain and impairment while also cervical spine range of motion enhancement and everyday mobility. More evidence for Muscle Energy Technique (MET) in treating such a condition was found. This case report describes muscular energy technique's effect on a patient who has been suffering from neck pain for a long time.
Case Presentation: At the previous three months, a 27-year-old female accountant in a hospital with extended periods of sitting while working on a computer presented to our facility with neck pain. Increase in pain with looking up.
Discussion: The therapy was well embraced through this patient to muscle energy technique resulting in a high degree of flexibility in the cervical spine, reduce pain and improves flexibility and strength.
Conclusion: Physiotherapy has a significant effect Pain, strength, and range of motion are all factors to consider. The findings of this case study indicate that a specific muscle energy technique It's possible that a routine will help to alleviate the problem of neck pain, improves strength and functional ability.
Sunlight Control of Ferromagnetic Damping in Photovoltaic/Ferromagnetic Heterostructures
Authors: Li Chunlei , Li Yaojin , Zhao Yifan , Du Yujing , Zhao Meng , Peng Wanjun , Wu Yangyang , Liu Ming , Zhou Ziyao 
Published: January 2022

AbstractThe inexorable trend of spintronics is to develop efficient spin‐control methods. For example, photovoltaic spintronics driven by sunlight has great potential in energy‐saving applications. Here, a ferromagnetic/PV heterojunction is prepared on Si‐substrate as Ta (4 nm)/Co (1 nm)/ZnO (from 10 to 58 nm)/PTB7‐Th: PC71BM/Pt (3 nm) to study how visible light affected magnetic dynamics. A linewidth variation as high as 812.55 Oe is achieved by optimizing the thickness of ZnO film used to enhance the electron transfer. Due to the photovoltaic effect, reversible ferromagnetic resonance (FMR) linewidth switches are displayed, which is attributed to the 3d orbitals occupancy of Co induced the TMS contribution and inhomogeneous broadening. This work proposes a sunlight controllable magnetic damping heterostructure for developing fast, small, energy‐efficient spintronics applications.
High‐Performance n‐Type Organic Electrochemical Transistors Enabled by Aqueous Solution Processing of Amphiphilicity‐Driven Polymer Assembly
Authors: Jeong Dahyun , Jo Il‐Young , Lee Seungjin , Kim Ji Hwan , Kim Youngseok , Kim Donguk , Reynolds John R. , Yoon Myung‐Han , Kim Bumjoon J. 
Published: January 2022

AbstractDespite the growing attention on organic electrochemical transistors (OECTs), most research has focused on the design of p‐type active materials, and the number of high‐performance n‐type materials is limited. Herein, a series of naphthalene diimide‐based polymers incorporated with asymmetrically branched oligo(ethylene glycol) (OEG) side chains are developed to enable green‐solvent‐processed, high‐performance n‐type OECTs. The branched OEG side chains afford sufficient solubility in eco‐friendly ethanol/water solvent mixtures. Importantly, taking advantage of the amphiphilic nature of OEG‐based polymers, ethanol/water solvents selectively solvate hydrophilic OEG side chains, while producing assembled π−π stacks of hydrophobic backbones. This enables highly ordered polymer packing with a preferential edge‐on orientation, and thus excellent lateral charge transport. In particular, the fine‐tuned OEG side chains of P(NDIMTEG‐T) provide compact backbone packing, effective polaron generation, and superior electrochemical stability with optimized swelling capability. The resultant n‐type OECT shows the best electrical/electrochemical performance in the family, represented by a high transconductance (gm) of 0.38 S cm−1 and a large figure‐of‐merit (µC*) of 0.56 F V−1 cm−1 s−1. This study demonstrates the use of aqueous processing in OECTs, for the first time, and suggests important guidelines for the design of n‐type organic mixed ionic‐electronic conductors with excellent OECT characteristics.
A Minimalist Binary Vaccine Carrier for Personalized Postoperative Cancer Vaccine Therapy
Authors: Zhao Jiayu , Xu Yudi , Ma Sheng , Wang Yibo , Huang Zichao , Qu Haoyuan , Yao Haochen , Zhang Yu , Wu Guanglu , Huang Leaf , Song Wantong , Tang Zhaohui , Chen Xuesi 
Published: January 2022

AbstractIn recent years, significant evolutions have been made in applying nanotechnologies for prophylactic and therapeutic cancer vaccine design. However, the clinical translation of nanovaccines is still limited owing to their complicated compositions and difficulties in the spatiotemporal coordination of antigen‐presenting cell activation and antigen cross‐presentation. Herein, a minimalist binary nanovaccine (BiVax) is designed that integrates innate stimulating activity into the carrier to elicit robust antitumor immunity. The authors started by making a series of azole molecules end‐capped polyethylenimine (PEI‐M), and were surprised to find that over 60% of the PEI‐M polymers have innate stimulating activity via activation of the stimulator of interferon genes pathway. PEI‐4BImi, a PEI‐M obtained from a series of polymers, elicits robust antitumor immune responses when used as a subcutaneously injected nanovaccine by simply mixing with ovalbumin antigens, and this BiVax system performs much better than the traditional ternary vaccine system, as well as, commercialized aluminum‐containing adjuvants. This system also enables the fast preparation of personalized BiVax by compositing PEI‐4BImi with autologous tumor cell membrane protein antigens, and a 60% postoperative cure rate is observed when combined with immune checkpoint inhibitors.
Revisiting the Preparation Progress of Nano‐Structured Si Anodes toward Industrial Application from the Perspective of Cost and Scalability
Authors: Li Haodong , Li Haoyu , Lai Yizhu , Yang Zhiwei , Yang Qing , Liu Yang , Zheng Zhuo , Liu Yuxia , Sun Yan , Zhong Benhe , Wu Zhenguo , Guo Xiaodong 
Published: January 2022

AbstractThe urgent demand for lithium ion batteries with high energy density is driving the increasing research interest in Si, which possesses an ultrahigh theoretical capacity. Though various modification strategies have been proposed from the aspects of electrolytes, binders, Si‐M alloys, and Si/C composites, the preparation of nano‐structured Si is the first step for industrial application, since it has the potential solve the intrinsic problem of severe volume change during the lithiation/delithiation process. A series of Si nanostructures including 0D (nanoparticles), 1D (nanowires, nanotubes), 2D (thin film), and 3D (porous structure) have been developed and displayed encouraging results. However, it remains a great challenge to realize industrial production with acceptable cost and batch stability. In this review, the preparation development of nano‐structured Si is revisited. After briefly introducing the market situation for nanostructured Si, the fabrication of various kinds of nanostructure Si are introduced, and the corresponding progress including ball milling, magnesium thermal reduction, temple method, chemical vapor deposition, and chemical etching are comprehensively reexamined and compared from the perspective of mechanism, cost, technical maturity, and recent development. Finally, the further directions of nano‐structured Si preparation toward industrial production are deeply discussed. This review of preparation of nanostructured Si helps to pave the way toward commercial application of high energy density Si‐anodes.
Organic Acid Etching Strategy for Dendrite Suppression in Aqueous Zinc‐Ion Batteries
Authors: Wang Wenxi , Huang Gang , Wang Yizhou , Cao Zhen , Cavallo Luigi , Hedhili Mohamed N. , Alshareef Husam N. 
Published: January 2022

AbstractAqueous zinc ion batteries (AZIBs) represent a promising technology for grid‐scale energy storage due to their innate safety, low cost, and environmental friendliness. However, planar Zn foil intrinsically suffers from limited ion and electron transport pathways, poor wettability, and surface passivation, preventing the homogenous deposition of metallic Zn and poor durability of AZIBs. Herein, a 3D Zn foil with hierarchical porous architecture is developed through a facile non‐aqueous organic acid etching strategy. The 3D Zn anode is pore‐rich and cavity‐rich, leading to significantly enhanced accessibility to aqueous electrolytes. Accordingly, this 3D Zn anode enables preferential plating of Zn in the porous texture with suppressed dendrite growth, as confirmed by ex situ scanning electron microscopy and finite element analysis. The cycle life of the 3D Zn anode is sustained over 930 and 1500 h at 4.0 mA cm−2‐2.0 mAh cm−2 and 1.0 mA cm−2‐1.0 mAh cm−2, respectively. Furthermore, the assembled 3D Zn and α‐MnO2 full batteries demonstrate a prolonged cycle life of 3000 cycles with improved rate performance. The etching strategy using non‐aqueous organic acid paves a new way to fabricate 3D metal anodes for Zn and other metal anode batteries.
Liquid Metal Remedies Silicon Microparticulates Toward Highly Stable and Superior Volumetric Lithium Storage
Authors: Zhao Ziyun , Han Junwei , Chen Fanqi , Xiao Jing , Zhao Yufei , Zhang Yifang , Kong Debin , Weng Zhe , Wu Shichao , Yang Quan‐Hong 
Published: January 2022

AbstractA silicon microparticulate material (SiMP) used as the anode for lithium‐ion batteries promises higher volumetric capacity and less interfacial reactions than its costly nanoparticulate counterpart. However, what mostly hinders its practical use is its expansion and pulverization during cycling that induces electrical disconnection and electrode polarization. A liquid metal (LM) is proposed as a remedy for these problems that acts as an adaptive conducting continuum to cure both short‐ and long‐range electrical disconnection. LM encapsulated in a carbon layer constructs a local electrical “ocean” adaptively connecting pulverized Si “islands” upon cycling. Furthermore, carbon nanofibers grown on the LM provide long‐range conducting bridges between the microparticulates, which allow the production of thick electrodes that can be used with SiMPs. With the increased tap densities (4.15 and 1.75 g cm−3 respectively for the composite and the electrode), these thick electrodes give highly stable and superior volumetric lithium storage. These results pave the way for practical compact lithium batteries with SiMPs that have a high‐volumetric energy density.
Parkinson Disease and Subthalamic Nucleus Deep Brain Stimulation: Cognitive Effects in GBA Mutation Carriers
Authors: Pal Gian , Mangone Graziella , Hill Emily J. , Ouyang Bichun , Liu Yuanqing , Lythe Vanessa , Ehrlich Debra , Saunders‐Pullman Rachel , Shanker Vicki , Bressman Susan , Alcalay Roy N. , Garcia Priscilla , Marder Karen S. , Aasly Jan , Mouradian M. Maral , Link Samantha , Rosenbaum Marc , Anderson Sharlet , Bernard Bryan , Wilson Robert , Stebbins Glenn , Nichols William C. , Welter Marie‐Laure , Sani Sepehr , Afshari Mitra , Verhagen Leo , de Bie Rob M.A. , Foltynie Tom , Hall Deborah , Corvol Jean‐Christophe , Goetz Christopher G. 
Published: January 2022

ObjectiveThis study was undertaken to compare the rate of change in cognition between glucocerebrosidase (GBA) mutation carriers and noncarriers with and without subthalamic nucleus deep brain stimulation (STN‐DBS) in Parkinson disease.MethodsClinical and genetic data from 12 datasets were examined. Global cognition was assessed using the Mattis Dementia Rating Scale (MDRS). Subjects were examined for mutations in GBA and categorized as GBA carriers with or without DBS (GBA+DBS+, GBA+DBS‐), and noncarriers with or without DBS (GBA‐DBS+, GBA‐DBS‐). GBA mutation carriers were subcategorized according to mutation severity (risk variant, mild, severe). Linear mixed modeling was used to compare rate of change in MDRS scores over time among the groups according to GBA and DBS status and then according to GBA severity and DBS status.ResultsData were available for 366 subjects (58 GBA+DBS+, 82 GBA+DBS‐, 98 GBA‐DBS+, and 128 GBA‐DBS‐ subjects), who were longitudinally followed (range = 36–60 months after surgery). Using the MDRS, GBA+DBS+ subjects declined on average 2.02 points/yr more than GBA‐DBS‐ subjects (95% confidence interval [CI] = −2.35 to −1.69), 1.71 points/yr more than GBA+DBS‐ subjects (95% CI = −2.14 to −1.28), and 1.49 points/yr more than GBA‐DBS+ subjects (95% CI = −1.80 to −1.18).InterpretationAlthough not randomized, this composite analysis suggests that the combined effects of GBA mutations and STN‐DBS negatively impact cognition. We advise that DBS candidates be screened for GBA mutations as part of the presurgical decision‐making process. We advise that GBA mutation carriers be counseled regarding potential risks associated with STN‐DBS so that alternative options may be considered. ANN NEUROL 2022;91:424–435