bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENDIDIKAN KESEHATAN UNTUK MENINGKATKAN PERILAKU PERSONAL HIGIENE SAAT MENSTRUASI BAGI SISWA SMP
Authors: Yuni Astuti  , Tuti Anggarawati  , Afriza Prima Safira  , Salsabila Lintang W  , Riskha Esnawati  , Bekti Sri Utami  , Diah Ayu P  
Published: June 2022

Menstruasi adalah masa perdarahan yang terjadi secara teratur setiap bulan yang disebabkan oleh pelepasan telur yang tidak dibuahi dari ovarium atau indung telur. Remaja putri yang sedang menstruasi harus menjaga kebersihan diri dan hygiene merupakan upaya untuk menjaga kebersihan diri dan kesehatan melalui perawatan diri. Perilaku hygiene saat menstruasi merupakan hal yang penting untuk diperhatikan oleh remaja SMP, jika remaja tidak melakukan personal hygiene saat menstruasi seperti tidak mengganti celana dalam saat mengganti pembalut, mengganti pembalut saat sudah penuh saja, dan jarang mandi dapat menimbulkan gangguan pada fungsi reproduksi. Hasil wawancara dengan salah pengurus PKK menyatakan bahwa siswa di RW 03 Kelurahan Mangunharjo Kecamatan Tembalang belum pernah mendapatkan penyuluhan kesehatan tentang perilaku personal hygiene pada saat menstruasi. Kegiatan pendidikan kesehatan ini bermanfaat bagi pengembangan pengetahuan dan keterampilan masyarakat khususnya remaja putri pada saat mendapatkan menstruasi. Dari hasil kegiatan ini pengetahuan remaja putri meningkat dari 30% menjadi 70% sedangkan keterampilan meningkat dari 20% menjadi 80%. Saran untuk kegiatan ini dapat ditindaklajuti secara simultan dan melibatkan seluruh elemen yang ada di keluarga dan masyarakat.
Aróstegui, J. L., Rusinek, G. & Fernández-Jiménez, A. (Eds.). (2021). Escuelas musicales. Buenas prácticas docentes en centros de Primaria y Secundaria que educan a través de la música. Octaedro.
Authors: Capistrán Gracia Raúl Wenceslao 
Published: June 2022

El libro Escuelas musicales. Buenas prácticas docentes en centros de Primaria y Secundaria que educan a través de la música, editado por José Luis Aróstegui Plaza (Universidad de Granada), Gabriel Rusinek Milnes (Universidad Complutense) y Antonio Fernández-Jiménez (Universidad de Granada), representa uno de los productos resultantes del proyecto de investigación con clave EDU2014-58066-P, titulado, “El Impacto de la Educación Musical en la Sociedad y en la Economía del Conocimiento” (IMPACTMUS). Ese proyecto fue estructurado en tres ejes de tipo complementario. Este libro presenta los resultados derivados del tercer eje, el cual se enfocó en identificar y analizar nueve propuestas educativo-musicales realizadas en España que han influido positivamente en la vida de los estudiantes, expuestas a manera de estudios de caso en siete capítulos. Adicionalmente, el libro incorpora cuatro capítulos más que, desde distintas perspectivas, lo complementan atinadamente.
INFLUÊNCIA DO ACESSO MINIMAMENTE INVASIVO NO SUCESSO DO TRATAMENTO ENDODÔNTICO: UMA REVISÃO SISTEMÁTICA DA LITERATURA
Authors: Dourado Martins Cerqueira Joana , De Souza Freitas Mirna , Machado de Oliveira Serra Joice , Nascimento Cerqueira Costa Rêuder , Silva Azevedo Alana de Cássia 
Published: June 2022

Introdução O sucesso do tratamento endodôntico baseia-se em uma sequência de etapas importantes que devem ser realizadas da forma correta. O acesso bem feito proporciona uma boa visualização do campo operatório que facilita a instrumentação e obturação dos condutos. Objetivo: Avaliar a influência do acesso minimamente invasivo no sucesso do tratamento endodôntico através de uma revisão sistematica da literatura. Materias e Métodos: Foi realizada uma revisão sistemática da literatura dos últimos 10 anos, coletadas nas bases de dados Science Direct, Lilacs, PubMed e SciELO. Ultilizando as palavras-chaves e selecionados os estudos In vitro. Resultados: 18 artigos compriram os criterios de inclusão e foram elegíveis para a revisão. Dentre os estudos selecionados 13 consideraram a influência do acesso minimamente invasivo sobe a resistência do dente, 03 sobre a limpeza dos canais radiculares e 02 sobre a preservação da anatomia dentária. Conclusão: De acordo com os resultados obtidos neste estudo, a endodontia minimamente invasiva preserva a anatomia dentária, porem não mostrou resultados significativos com relação a resistência e limpeza dos canais.
Palavras-chaves: endodontia, cavidade pulpar, preparo do canal radicular
PERFIL CLÍNICO E EPIDEMIOLÓGICO DOS PACIENTES ATENDIDOS EM UMA CLÍNICA DE ENDODONTIA
Authors: Dourado Martins Cerqueira Joana , Pedreira Pereira dos Santos Gabriela , Oliveira Braz Carvalho Luanna , Cruz Fonseca Maria Verenna , Vasquez Fernandes Bastos Nagahama Maria do Carmo , De Matos Vilas Boas Aline 
Published: June 2022

Introdução: A terapia endodôntica tem a função de proporcionar a desinfecção dos canais contaminados, sendo o acompanhamento clínico e radiográfico crucial para a avaliação do sucesso do tratamento. Objetivo: Avaliar os tratamentos endodônticos realizados pelos acadêmicos do curso de Odontologia da rede UniFtc do campus Feira de Santana, no período de 2019 e 2021. Metodologia: Foram analisados 57 prontuários de pacientes, considerando as variáveis sócio-demográficas e clínicas. Resultados: Foram incluídos na pesquisa 41 pacientes que realizaram TE. Dentre eles 73,1% era do sexo feminino e 43,3% com idades de 30 a 40 anos. A causa mais comum que levou a tratamento foi a cárie em 58,8% dos casos, tornando o diagnóstico de Pulpite Irreversível Assintomática mais frequente (41,1%) e os Incisivos Centrais (28,5%) os mais acometidos. O tratamento foi realizado em 03 sessões em 60% dos casos e somente 40% desses dentes foram reabilitados definitivamente. Conclusão: Foi observado que a maior parte dos tratamentos endodônticos realizados na clínica escola da UniFtc no período de 2019 a 2021 foi realizado em mulheres jovens, sendo clinicamente diagnosticados com pulpite irreversível assintomática, tratados em 03 sessões, com preenchimento adequado dos canais e não reabilitados definitivamente.
Palavras chave: Endodontia. Sucesso. Obturação do canal radicular
AVALIAÇÃO DA FORMA E PREENCHIMENTO DO CANAL RADICULAR COM HIDRÓXIDO DE CÁLCIO COM DIFERENTES TÉCNICAS
Authors: Bastos Nagahama Maria do Carmo Vasquez Fernandes , Fiais Costa Suelen , De Lima Silva Fabiane , Hongyu Kuang 
Published: June 2022

Em virtude das dificuldades para debelar as infecções endodônticas, exclusivamente através do preparo químico-mecânico, deve-se levar em consideração a utilização de uma medicação intracanal biocompatível como o hidróxido de cálcio. Para que o hidróxido de cálcio atue é imprescindível que o sistema de canais radiculares seja preenchido o mais completo possível, servindo, assim, como barreira física e química dificultando a penetração dos microrganismo. O objetivo de estudo desta pesquisa, foi avaliar a qualidade e forma de preenchimento do canal radicular com hidróxido de cálcio com três técnicas diferentes. O presente estudo foi aprovado no Comitê de Ética sob o parecer de n° 2.857.715.Foram selecionados 90 dentes unirradiculares, através de um banco de dentes. Estes dentes foram separados por grupo, sendo utilizados 3 tipos de técnicas diferentes para preenchimento do canal com hidróxido: usando-se - Lima, usando-se 2- Lentulo e usando-se 3- Mc Spadden. Observou-se que o lentulo teve melhor preenchimento em lateralidade e profundidade do canal principal e secundário, sendo averiguado que dentre os grupos de dentes, teve diferenças significativas comparadas o Mc Spadden. Esses índices revelam o quanto é importante a escolha da técnicas de preenchimento, para favorecer a qualidade do sucesso no tratamento, pois o seu correto preenchimento favorece a função de combater o crescimento de microrganismo dentro do canal.
Factors Contributing to Unsafe Food Processing and Preservation among Food Handlers in Port Harcourt, Nigeria
Authors: Obioma L. Ekweh , Inumanye N. Ojule 
Published: June 2022

Background: Unsafe food processing and preservation among food handlers has been one of the common causes of food and waterborne diseases. This study aimed to identify factors contributing tounsafe food processing and preservation practices among food handlers in Obio-Akpor LGA of Rivers state.
Materials and Methods: The study was a descriptive cross-sectional study whichassessed 365 food handlers in Obio/Akpor Local Government Area of Port Harcourt, Nigeria. A semi-structured questionnaire was used to collect relevant data. Quantitative datawas presented as frequencies and percentages. All statistical tests were set at a significance level of p< 0.05.
Results: Findings show that out of the 365 food handlers who participated in the study, only 43.0% had a set of standard practice guidelines. 47.4% of the food handlers practiced unsafe food processing and preservation methods.Duration of practice for more than 5 years (63.6% vs. 36.4%; p=0.04) and scale of business (large/small) (turnover>NGN50, 000.00) ((58.4%, vs. 10.4%, p=0.05) were significantly associated with unsafe food processing and preservation practicesas handlers who have been in the food business longer and those with larger scale food outlets tended to have better standards.
Conclusion: Unsafe food processing practices exist among food handlers with nearly half of the food handlers studied having poor practices. Inadequate working experience and the presence of more small and medium scale businesses was found to be the factors affecting unsafe food processing and preservation practices in our locality.
Malaria Prevalence and Anemia Status of Children Attending a Health Facility in Yola
Authors: Isa Halima , Bashir Mohammed , Adedeji Babajide A. 
Published: June 2022

Background: Malaria and anemia among children especially those that are <5 years of age are still diseases of public health concern. This study was designed to determine the effect of malaria on the anaemia status of under five children attending a health facility in Yola, Adamawa state, Nigeria.
Methods: Blood samples were collected from out-patient under five children reporting at the paediatric unit of the hospital. The blood samples were screened for the presence of malaria parasites by microscopy while their anaemia status was determined by checking their packed cell volume (PCV). The prevalence rate of malaria, anemia, and malaria-anemia was calculated. The level of significance was determined using chi-square (χ2) statistics.
Results: Of the 200 samples, 124 (62%) were positive for malaria, with the prevalence being higher in males. 103 of the patients had PCV values below 33% giving an overall anaemia prevalence of 51.5% of anemia cases. The results obtained show that the three forms of anaemia – mild, moderate and severe were seen in the sampled population with moderate anaemia being the most prevalent (29.0%); the results also show that malaria parasite density has an effect on the PCV levels of the children at p= .0001, and patients with severe anaemia had the highest parasite loads.
Conclusion: Malaria remains a common infection among under five children in this environment and predisposes them to having anaemia. Moderate malaria is also the most common form of anaemia seen in malaria positive children.
Microbiological Analysis, Quality and Safety Evaluation of Commercially Sold Medicinal Herbal Cocktails from Local Herb Seller within Akoko South West, Ondo State, Nigeria
Authors: Osuntokun O. T. , Thonda O. A. , Ajadi F. A. , Wilkie E. D. , Oluwatuyi B. B. 
Published: June 2022

The use of herbal plants has been growing rapidly worldwide; it has been widely and extensively used locally as medicinal products in the treatment of different diseases. The extensive use of herbal medicinal products in the treatment and management of disease made it imperative to investigate the microbial analysis of locally prepared herbal cocktails sold in Akoko South West. Nigeria Different samples of local herbs were randomly collected from different locations into sterile polythene and transported to the microbiology laboratory for further microbial analysis. The samples were analyzed using pour plate techniques. The bacteria isolates were characterized and identified based on their colonial, morphological characteristics, and biochemical tests according to Bergey’s Manual of Determinative Bacteriology. Antibiotic susceptibility test of the isolates was carried out using the disc agar diffusion method. The killing rate and growth dynamics of the bacterial isolates were determined using a Ultra-violet spectrophotometer. Twelve species of the isolates were recovered. Staphylococcus aureus and Clostridium sporogenes showed a high susceptibility rate to Ciprofloxacin, levofloxacin, Gentamicin, ampiclox, rifampicin, and Amoxillin while they were both resistant to Streptomycin, Norfloxacin, chloramphenicol, and Erythromycin. The Gram-positive isolates were 100% resistant to Norfloxacin, chloramphenicol, Erythromycin and 100% sensitive to Ciprofloxacin. UV-VIS spectrophotometer was used to measure the material of absorbance and quantitative analysis at the visible or ultraviolet light (200 ~ 760nm). Ultra-violet (UV) spectrophotometer was used to determine the growth dynamics and killing kinetics of isolated organisms, and to predict the wavelength of killing ratio of organisms isolated from the herbal cocktail. The addition of antibiotics to the isolated organisms at the 84th-hour speed up the death rate of the isolates from commercially sold herbal cocktail between 450-480nm wavelengths. Water used for production of herbal cocktail needed prolong hours of exposure to Ultraviolet rays/ light is necessary, to reduce microbial load drastically, with a great effect on the quality and safety of commercially sold herbal cocktail. There is a need for constant monitoring and quality control of herbal medicinal products being manufactured, sold, and used in Nigeria so as to reduce and or eradicate the effect of the organisms on human health.
Effect of Extraction Techniques and Evaluation of Antimicrobial Activity of Argemone mexicana L. Leaves and Roots Extracts in Different Solvents
Authors: Kumari Sachin , Sindhu Meena , Goel Neha , Panghal Monika , Singh Sushila , Rani Indu 
Published: June 2022

Aim: The main objective of the study is to estimate the effect of extraction techniques and antimicrobial activity of different solvent extract of A. mexicana leaves and roots.
Study Design: The research is experimental in nature.
Place and Duration of Study: Department of Chemistry and Microbiology at CCSHAU, Hisar, between late 2020 and January 2022.
Methodology: The leaves and roots of A. mexicana were harvested for this study. Shade dried roots and leaves were cut into small pieces of 2-3 inches and processed into powder using a mixer grinder. Soxhlet extraction and microwave-assisted extraction procedures were used to extract leaves and roots in solvents such as acetone, methanol, and water. The antimicrobial activity of the roots and leaves extracts were evaluated against Gram +ve bacteria (Xanthomonas campesteris, Bacillus cereus, Staphylococcus aureus) and fungal species (Fusarium oxysporum, Macrophomina phaseolina and Candida albicans) and their zones of inhibition in mm are measured by Agar well diffusion method.
Results: Soxhlet extraction technique gave better extract yield 12.19 g /100 g and 8.54 g / 100 g while microwave-assisted extraction gave 8.88 g / 100 g and 6.94 g / 100 g for leaves and roots respectively. The methanoilc root and leaves extracts exhibited higher antimicrobial activity followed by acetone and water extracts.
Conclusion: The result of the investigation showed that extraction techniques considerably affected extraction yield and antimicrobial activity. Soxhlet extraction is better one extraction method among these two and methanolic extract of leaves was found to be good antimicrobial followed by acetone and aqueous.
Predicting Sustained Clinical Response to Rituximab in Moderate to Severe Systemic Manifestations of Primary Sjögren Syndrome
Authors: Pepple Sophanit , Arnold Jack , Vital Edward M. , Rawstron Andrew C. , Pease Colin T. , Dass Shouvik , Emery Paul , Md Yusof Md Yuzaiful 
Published: June 2022

ObjectiveTo assess outcomes of repeat rituximab cycles and identify predictors of sustained clinical response in systemic manifestations of primary Sjögren syndrome (pSS).MethodsAn observational study was conducted in 40 rituximab‐treated patients with pSS. Clinical response was defined as a 3‐point or more reduction in the European League Against Rheumatism (EULAR) Sjögren Disease Activity Index (ESSDAI) at 6 months from baseline. Peripheral blood B cells were measured using highly sensitive flow cytometry. Predictors of sustained response (within two rituximab cycles) were analyzed using penalized logistic regression.ResultsThirty‐eight out of 40 patients had moderate to severe systemic disease (ESSDAI >5). Main domains were articular (73%), mucocutaneous (23%), hematological (20%), and nervous system (18%). Twenty‐eight out of 40 (70%) patients were on concomitant immunosuppressants. One hundred sixty‐nine rituximab cycles were administered with a total follow‐up of 165 patient‐years. In cycle 1 (C1), 29/40 (73%) achieved ESSDAI response. Of C1 responders, 23/29 received retreatment on clinical relapse, and 15/23 (65%) responded. Of the 8/23 patients who lost response, these were due to secondary non‐depletion and non‐response (2NDNR; 4/23 [17%] as we previously observed in systemic lupus erythematosus with antirituximab antibodies, inefficacy = 2/23, and other side effects = 2/23). Within two cycles, 13/40 (33%) discontinued therapy. In multivariable analysis, concomitant immunosuppressant (odds ratio 7.16 [95% confidence interval: 1.37–37.35]) and achieving complete B‐cell depletion (9.78 [1.32–72.25]) in C1 increased odds of response to rituximab. At 5 years, 57% of patients continued on rituximab.ConclusionOur data suggest that patients with pSS should be co‐prescribed immunosuppressant with rituximab, and treatment should aim to achieve complete depletion. About one in six patients develop 2NDNR in repeat cycles. Humanized or type 2 anti‐CD20 antibodies may improve clinical response in extra‐glandular pSS.
Bioprinted Living Coral Microenvironments Mimicking Coral‐Algal Symbiosis
Authors: Wangpraseurt Daniel , Sun Yazhi , You Shangting , Chua Sing‐Teng , Noel Samantha K. , Willard Helena F. , Berry David B. , Clifford Alexander M. , Plummer Sydney , Xiang Yi , Hwang Henry H. , Kaandorp Jaap , Diaz Julia M. , La Jeunesse Todd C. , Pernice Mathieu , Vignolini Silvia , Tresguerres Martin , Chen Shaochen 
Published: June 2022

AbstractThe coral‐algal symbiosis is the biological engine that drives one of the most spectacular structures on Earth: the coral reef. Here, living coral microhabitats are engineered using 3D bioprinting, as biomimetic model system of the coral‐algal symbiosis. Various bioinks for the encapsulation of coral photosymbiotic microalgae (Breviolum psygmophilum) are developed and coral mass transfer phenomena are mimicked by 3D bioprinting coral tissue and skeleton microscale features. At the tissue–seawater interface, the biomimetic coral polyp and connective tissue structures successfully replicate the natural build‐up of the O2 diffusive boundary layer. Inside the bioprinted construct, coral‐like microscale gastric cavities are engineered using a multi‐material bioprinting process. Underneath the tissue, the constructs mimic the porous architecture of the coral aragonite skeleton at the micrometer scale, which can be manipulated to assess the effects of skeletal architecture on stress‐related hydrogen peroxide (H2O2) production. The bioprinted living coral microhabitats replicate the diffusion‐related phenomena that underlie the functioning and breakdown of the coral‐algal symbiosis and can be exploited for the additive manufacturing of synthetic designer corals.
Cascade Reaction of “Mn2+‐Catechol” Triggered by H2O2 to Integrate Firm Tumor Vessel Embolization and Hypoxic Response Relief
Authors: Fan Man , Liu Yiming , Ren Yanqiao , Gan Lu , Yang Yajiang , Wang Hong , Liao Yonggui , Yang Xiangliang , Zheng Chuansheng , Wang Qin 
Published: June 2022

AbstractTranscatheter arterial embolization (TAE) therapy requires firm and long‐term vessel embolization without recanalization. However, firm embolization usually leads to unanticipated hypoxic response which promotes tumor recurrence and metastasis. Herein, an injectable thermosensitive hydrogel containing catechol groups and Mn2+ (PNDM) has been developed to enhance embolization and inhibit hypoxic response utilizing augmented H2O2 after TAE. This novel embolic agent converts H2O2 into hydroxyl radicals via Mn2+‐dependent Fenton‐like reaction, which are subsequently scavenged through a “catechol‐quinone” transition to suppress hypoxic responses. Quinone structure can not only make hydrogel internal structure more compact, but also enhance hydrogel adhesion to vessel wall. In vivo experiments confirm that the rabbit renal artery can be firmly embolized for 84 days. Studies in liver VX2 tumor‐bearing rabbits demonstrate that the PNDM‐based TAE can promote tumor necrosis, inhibit angiogenesis and tumor metastasis, and greatly prolong rabbit survival. This strategy opens new sights in the TAE therapy for liver cancer.
A Thermal‐Pressed Strategy for Crystal Growth and Boundaries Self‐Fusion of Mixed‐Halide Perovskite Films against Halide Phase Segregation
Authors: Zhang Teng , Zhang Li , Zhu Guanglu , Cui Deliang , Wang Qilong , Lian Gang , Zheng Zhaoke , Yu Haohai 
Published: June 2022

AbstractAll‐inorganic mixed‐halide perovskite CsPbI3−xBrx materials have attracted extensive attention in optoelectronics due to upgraded stability and tuned bandgap. Unfortunately, undesired halide phase segregation by ion migration under illumination deteriorates photoelectrical performance and long‐term stability of devices. The severity of phase segregation is prone to occur at grain boundaries and relies on surface/interface defects. Herein, a thermal‐pressed (TP) crystal‐growth strategy is proposed to realize sufficient grain growth and boundary fusion simultaneously in a series of CsPbI3−xBrx films. The large‐sized crystals (20–40 µm), self‐fused boundaries, and single‐crystal‐like surface effectively block photoinduced ion migration. The TP‐based CsPbI3−xBrx films maintain excellent long‐life photostability over one year and exhibit markedly suppressed halide phase segregation under continuous laser illumination. Consequently, the TP‐based photodetector devices exhibit superior long‐term stability under laser illumination with different wavelengths.