bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploration of a Swedish community-based family-oriented setting for promoting healthy food habits: professionals’ experiences
Authors: Mulkerrins Isabelle , Gripeteg Lena , Berg Christina 
Published: March 2022

Summary
Health is created in everyday life and settings, where food literacy (FL) and health literacy (HL) are recognized as important for autonomy over one’s own health. Though it is acknowledged that bridging the gap between healthcare settings and community settings may be necessary to reach those requiring extra support. Open preschool (OP) is a low threshold community setting which parents with their young children can visit voluntarily, where the various activities offered can be opportunities to address topics related to food and health. The aim of this study is to explore preschool teachers and health practitioners’ thoughts and experience of OP as a setting for health promotion, with focus on food and eating. The study is localized to OP’s in a multicultural district in Gothenburg, Sweden. Semi-structured interviews were conducted with three preschool teachers and seven health practitioners (one dental hygienist, three dietitians and three public health strategists). With an inductive approach, data were analysed using qualitative content analysis. From the perspective of teachers and health practitioners, the findings indicate that OP can be a setting for mutual learning in a supportive environment. OP provides various possibilities for improved FL and HL by linking health practitioners with families, providing the opportunity to socialize and by eating together. The results also reveal that language barriers can sometimes hinder communication, and that OP does not reach all families. Continuous collaboration between OP and health organizations and practitioners along with regular use of intercultural mediators is recommended by the professionals.
Radical surgery for a mitral valve intimal sarcoma: serial patch repair of the annulus and atrium
Authors: Matsuzaki Kanji , Mitomi Kisato , Imai Akito , Watanabe Yasunori 
Published: March 2022

Abstract
We report the rare case of a 48-year-old woman with a cardiac intimal sarcoma occupying the mitral valve and the left atrial roof. We resected the tumour in one block without residual lesions. The anterior mitral annulus and left atrial roof were serially repaired with the bovine pericardium, and a mechanical prosthesis was implanted in the reconstructed mitral annulus. The patient remains alive without recurrence for more than 1 and a half years postoperatively. We performed radical surgery for a mitral valve intimal sarcoma, and serial patch repair of the anterior mitral annulus and left atrial roof was a useful technique.
A 1D linearization–based MILP–NLP method for short-term hydrothermal operation
Authors: Kang Chuanxiong , Wu Shaofei , Gul Eid , Yu Xiang , Ren Pingan 
Published: March 2022

Abstract
The scheduling and optimization of short-term hydrothermal operation utilize the water resources efficiently and magnify the benefits of hydro energy while reducing the fuel and operation cost of thermal power plants. Short-term hydrothermal operation is a complex non-linear and non-convex optimization problem, which reflects thermal valve point effects, load balances, generation bounds and water transport delay. It is highly important and significant to figure out these problems to maximize the benefits of hydrothermal joint operation for energy saving, emission reduction and efficient resources management. This article presents a 1D linearization technique to deal with the non-linear function of two variables, a combined mixed-integer linear programming (MILP) and non-linear programming (NLP) method to solve this problem. The applied method introduces integer variables to linearize the original model into a MILP one; the solution by MILP is then corrected and re-optimized to formulate a feasible solution to warm start NLP. The 1D linearization method is efficient for MILP as it avoids the coupled relationships of integer variables, and the NLP local search is used to correct the influence of linearization errors and search further. The case studies show that the result derived by the 1D linearization–based MILP–NLP method is superior to that of previous works. The method is tested with different linearization accuracy, and the results demonstrate that the method is stable. The presented technique is promising for real-world hydrothermal operation and related problems.
Word Measures on Symmetric Groups
Authors: Hanany Liam , Puder Doron 
Published: March 2022

AbstractFix a word $ w $ in a free group $ \textbf {F}$ on $r$ generators. A $w$-random permutation in the symmetric group $S_{N}$ is obtained by sampling $r$ independent uniformly random permutations $ \sigma _{1},\ldots ,\sigma _{r}\in S_{N}$ and evaluating $w\left (\sigma _{1},\ldots ,\sigma _{r}\right )$. In [39, 40], it was shown that the average number of fixed points in a $w$-random permutation is $1+\theta \left (N^{1-\pi \left (w\right )}\right )$, where $ \pi \left (w\right )$ is the smallest rank of a subgroup $H\le \textbf {F}$ containing $w$ as a non-primitive element. We show that $ \pi \left (w\right )$ plays a role in estimates of all stable characters of symmetric groups. In particular, we show that for all $t\ge 2$, the average number of $t$-cycles is $ \frac {1}{t}+O\left (N^{-\pi \left (w\right )}\right )$. As an application, we prove that for every $s$, every $ \varepsilon&gt;0$ and every large enough $r$, Schreier graphs with $r$ random generators depicting the action of $S_{N}$ on $s$-tuples, have 2nd eigenvalue at most $2\sqrt {2r-1}+\varepsilon $ asymptotically almost surely. An important ingredient in this work is a systematic study of not necessarily connected Stallings core graphs.
Counterexamples for High-Degree Generalizations of the Schrödinger Maximal Operator
Authors: An Chen , Chu Rena , Pierce Lillian B 
Published: March 2022

Abstract
In 1980 Carleson posed a question on the minimal regularity of an initial data function in a Sobolev space $H^s({\mathbb {R}}^n)$ that implies pointwise convergence for the solution of the linear Schrödinger equation. After progress by many authors, this was recently resolved (up to the endpoint) by Bourgain, whose counterexample construction for the Schrödinger maximal operator proved a necessary condition on the regularity, and Du and Zhang, who proved a sufficient condition. Analogues of Carleson’s question remain open for many other dispersive partial differential equations. We develop a flexible new method to approach such problems and prove that for any integer $k\geq 2$, if a degree $k$ generalization of the Schrödinger maximal operator is bounded from $H^s({\mathbb {R}}^n)$ to $L^1(B_n(0,1))$, then $s \geq \frac {1}{4} + \frac {n-1}{4((k-1)n+1)}.$ In dimensions $n \geq 2$, for every degree $k \geq 3$, this is the first result that exceeds a long-standing barrier at $1/4$. Our methods are number-theoretic, and in particular apply the Weil bound, a consequence of the truth of the Riemann Hypothesis over finite fields.
The bla and mec families of β-lactam resistance genes in the genera Macrococcus, Mammaliicoccus and Staphylococcus: an in-depth analysis with emphasis on Macrococcus
Authors: Schwendener Sybille , Perreten Vincent 
Published: March 2022

Abstract
β-Lactamases (Bla) and low-affinity penicillin-binding proteins (PBP2A) are responsible for β-lactam resistance in the genera Macrococcus, Mammaliicoccus and Staphylococcus. These resistance mechanisms are in most species acquired through mobile genetic elements that carry a blaZ-like β-lactamase gene for penicillin resistance and/or a mec gene (mecA, mecB, mecC,mecD) encoding a PBP2A for resistance to virtually all classes of β-lactams. The mecA and mecC genes can be acquired through staphylococcal cassette chromosome mec (SCCmec) elements in Staphylococcus and Mammaliicoccus. The mecB and mecD genes are found in Macrococcus on SCCmec elements, as well as on unrelated mecD-carrying Macrococcus resistance islands (McRImecD) and large mecB-carrying plasmids. This review provides a phylogenetic overview of Macrococcus, Mammaliicoccus and Staphylococcus species and an in-depth analysis of the genetic structures carrying bla and mec genes in these genera. Native bla genes were detected in species belonging to the novobiocin-resistant Staphylococcus saprophyticus group and Mammaliicoccus. The evolutionary relatedness between Macrococcus and Mammaliicoccus is illustrated on the basis of a similar set of intrinsic PBPs, especially, the presence of a second class A PBP. The review further focuses on macrococcal elements carrying mecB and mecD, and compares them with structures present in Staphylococcus and Mammaliicoccus. It also discusses the different recombinases (ccr of SCCmec) and integrases (int of McRI) that contribute to the mobility of methicillin resistance genes, revealing Macrococcus as an important source for mobilization of antibiotic resistance genes within the family of Staphylococcaceae.
Insecticide Resistance and Control Failure Likelihood Analysis in Plutella xylostella (Lepidoptera: Plutellidae) Populations From Taiwan
Authors: Pudasaini Rameshwor , Chou Ming-Yi , Wu Tsung-Jung , Dai Shu-Mei 
Published: March 2022

Abstract
The status of insecticide resistance levels is important for applying suitable pest management approaches. The present study investigated the insecticide resistance of Plutella xylostella (Linnaeus) (Lepidoptera: Plutellidae) populations from five major cruciferous growing areas in Taiwan. The surveyed locations were distributed from central to southern Taiwan and included Taichung, Changhua, Yunlin, Chiayi, and Kaohsiung. High levels of resistance to spinosad, indoxacarb, metaflumizone, and chlorantraniliprole were recorded among the surveyed populations except in Taichung. The resistance ratios ranged from 2.376 to 1,236-fold for spinosad and 24.63–1,511-fold for indoxacarb. Similarly, those for metaflumizone and chlorantraniliprole, were 2.563–76.21- and 4.457–683.0-fold, respectively. However, Bacillus thuringiensis subsp. aizawai, Bacillus thuringiensis subsp. kurstaki, emamectin benzoate, and diafenthiuron were still relatively effective against most field populations of P. xylostella. After approximately 10 generations of being maintained in the laboratory without exposure to insecticides, the resistance ratios of the Kaohsiung and Changhua populations declined to approximately 1.4–10-fold, and insecticides with control failure likelihood also began to show a negligible risk of control failure. Although spinosad, indoxacarb, metaflumizone, and chlorantraniliprole have lost their effectiveness in most field populations of P. xylostella in Taiwan, their effectiveness may be recovered in the absence of insecticide-selection pressure for approximately 10 generations. Therefore, we suggest that a constant survey of insecticide resistance and well-designed insecticide rotation based on the survey results are necessary for the effective control and insecticide resistance management of P. xylostella.
Transcriptomic Analysis Reveals Potential Candidate Pathways and Genes Involved in Toxin Biosynthesis in True Toads
Authors: Firneno Thomas J , Ramesh Balan , Maldonado Jose A , Hernandez-Briones Alejandro I , Emery Alyson H , Roelke Corey E , Fujita Matthew K 
Published: March 2022

Abstract
Synthesized chemical defenses have broadly evolved across countless taxa and are important in shaping evolutionary and ecological interactions within ecosystems. However, the underlying genomic mechanisms by which these organisms synthesize and utilize their toxins are relatively unknown. Herein, we use comparative transcriptomics to uncover potential toxin synthesizing genes and pathways, as well as interspecific patterns of toxin synthesizing genes across 10 species of North American true toads (Bufonidae). Upon assembly and annotation of the 10 transcriptomes, we explored patterns of relative gene expression and possible protein–protein interactions across the species to determine what genes and/or pathways may be responsible for toxin synthesis. We also tested our transcriptome dataset for signatures of positive selection to reveal how selection may be acting upon potential toxin producing genes. We assembled high-quality transcriptomes of the bufonid parotoid gland, a tissue not often investigated in other bufonid-related RNAseq studies. We found several genes involved in metabolic and biosynthetic pathways (e.g., steroid biosynthesis, terpenoid backbone biosynthesis, isoquinoline biosynthesis, and glucosinolate biosynthesis) that were functionally enriched and/or relatively expressed across the 10 focal species that may be involved in the synthesis of alkaloid and steroid toxins, as well as other small metabolic compounds that cause distastefulness in bufonids. We hope that our study lays a foundation for future studies to explore the genomic underpinnings and specific pathways of toxin synthesis in toads, as well as at the macroevolutionary scale across numerous taxa that produce their own defensive toxins.
Water Rights Struggles in Johannesburg and Detroit Revisited: Looking Beyond Courts at the Politics and Power of Rights-Based Legal Mobilization in a Neoliberal Global Order: A ‘Powerpack’ Analysis
Authors: Dugard Jackie 
Published: March 2022

Abstract
Responding to the limits of court-based analyses and top-down position-taking in prevailing legal mobilization scholarship, this article goes beyond the courtroom to explore the value of rights-based legal mobilization from the perspective of those engaged in the campaigns to challenge racialized water disconnection in Johannesburg (2004–9) and Detroit (2014–). Against the backdrop of the ‘losing’ cases of Mazibuko and Lyda, the article finds evidence in the feedback from protagonists, of the relevance of rights-based mobilization notwithstanding the judicial defeats. The value of legal mobilization ascribed by affected communities and their allies aligns with the understanding of law as a form of political power in a dialectical relationship between structure and agency (Crawford and Andreassen 2013: 8–9). Using an expanded version of the ‘power cube’ (Gaventa 2006 and 2005), referred to here as the ‘powerpack’, the article engages in a bottom-up nuanced analysis of the multi-dimensional power of legal mobilization. In doing so, it contributes towards a deeper understanding of the transformative potential of rights-based mobilization for egalitarian socio-economic change.
Ecocide — Puzzles and Possibilities
Authors: Robinson Darryl 
Published: March 2022

Abstract
Popular interest in a new crime of ‘ecocide’ has recently surged. The proposed crime seeks to repudiate and stigmatize the most egregious environmental wrongdoing and would complement other efforts to curb the ongoing destruction. In June 2021, an international panel proposed a definition of the crime. Initial academic commentaries, many of them critical, reflect entirely understandable first reactions. However, combining international criminal law (ICL) and environmental law raises fascinating new issues that are not initially obvious. In this article, I survey the main issues in defining ecocide. For example, is a crime of ecocide a worthy idea? Is the best approach to amend the ICC Statute or to start with a smaller group of supportive states? I also introduce the main drafting options and controversies. The hardest puzzle, by far, is how to align ecocide with environmental law. Some seemingly simple solutions would entail rejecting environmental law; I argue that there are principled, normative, and strategic reasons why a crime of ecocide should reflect environmental law, not reject it. I show that each available solution invites plausible concerns. Thus, a conversation about defining ecocide must be a nuanced one about which options are least problematic. I outline possible future directions for exploration; with further deliberation, more elegant criteria may yet be found.
Caffeic acid regulates glucose homeostasis and inhibits purinergic and cholinergic activities while abating oxidative stress and dyslipidaemia in fructose-streptozotocin-induced diabetic rats
Authors: Salau Veronica F , Erukainure Ochuko L , Ijomone Omamuyovwi M , Islam Md. Shahidul 
Published: March 2022

Abstract

Objectives
The antidiabetic potential of caffeic acid in fructose/streptozotocin-induced type 2 diabetic rats was examined in this study.

Methods
Male Sprague-Dawley rats were supplied with 10% fructose solution for 14 days followed by an intraperitoneal injection of 40 mg/kg bw streptozotocin to induce type 2 diabetes (T2D). Rats were treated with both low (150 mg/kg bw) and high (300 mg/kg bw) doses of caffeic acid for 5 weeks, while the positive control group was treated with metformin (200 mg/kg bw).

Key findings
Treatment with caffeic acid significantly decreased blood glucose levels and elevated serum insulin levels while improving glucose tolerance, pancreatic β-cell function and morphology. It also led to a significant reduction of serum cholesterol, triglyceride, LDL-cholesterol, ALT, AST, creatinine, urea and uric acid levels, while increasing HDL cholesterol levels. Caffeic acid significantly (P &lt; 0.05) elevated hepatic glycogen level, serum and pancreatic glutathione level, superoxide dismutase and catalase activities with a concomitant decrease in malondialdehyde level, α-amylase, lipase, adenosine triphosphatase (ATPase), ectonucleoside triphosphate diphosphohydrolase (ENTPDase), 5ʹ-nucleotidase (5ʹ-NTD) and acetylcholinesterase activities.

Conclusion
The results suggest caffeic acid as a potent natural product with therapeutic effects against T2D. Further molecular and clinical studies are, however, required to ascertain these findings.
Building Peshawar: Labor, Security, and Infrastructure at the Edge of Empire
Authors: Lanzillo Amanda 
Published: March 2022

Abstract
This article focuses on the recruitment and organization of labor for projects of colonial state infrastructure in the city of Peshawar between 1849 and 1947. Providing access to the Khyber Pass—and thus Afghanistan—Peshawar was an urban center from which the colonial state sought to organize security on the Indo-Afghan frontier. Peshawari laborers, recruited to support the city’s large colonial military cantonment, railways, jail, and other infrastructure projects, were regulated according to colonial narratives about the security threats posed by the city’s geography and ethnic composition. This article contributes to our understanding of the labor of colonial security and border-making by uncovering the circular logic that connected security and labor in colonial-era Peshawar. The colonial state sought to build physical infrastructure to protect the city from the perceived threats posed by the Indo-Afghan frontier. But to build this infrastructure of security, colonial administrators relied on a porous border. Through the porous border they recruited labor from regional populations who they characterized as intrinsically prone to violence or difficult to discipline, spurring a continuous expansion of security infrastructure. Therefore, though an analysis of how laborers were recruited for state projects, the article argues that the colonial regime reified ethnic and social hierarchies within the city.
In situpod growth rate reveals contrasting diurnal sensitivity to water deficit inPhaseolus vulgaris
Authors: Merchant Andrew , Smith Millicent R , Windt Carel W 
Published: March 2022

AbstractThe development of reproductive tissues determines plant fecundity and yield. Loading of resources into the developing reproductive tissue is thought to be under the co-limiting effects of source and sink strength. The dynamics of this co-limitation are unknown, largely due to an inability to measure the flux of resources into a developing sink. Here we use nuclear magnetic resonance (NMR) sensors to measure sink strength by quantifying rates of pod dry matter accumulation (pod loading) in Phaseolus vulgaris at 13-min intervals across the diel period. Rates of pod loading showed contrasting variation across light and dark periods during the onset of water deficit. In addition, rates of pod loading appeared decoupled from net photosynthetic rates when adjusted to the plant scale. Combined, these observations illustrate that the rate of pod development varies under water limitation and that continuous, non-invasive methodologies to measure sink strength provide insight into the governing processes that determine the development of reproductive tissues.
A model-guided holistic review of exploiting natural variation of photosynthesis traits in crop improvement
Authors: Yin Xinyou , Gu Junfei , Dingkuhn Michael , Struik Paul C 
Published: March 2022

AbstractBreeding for improved leaf photosynthesis is considered as a viable approach to increase crop yield. Whether it should be improved in combination with other traits has not been assessed critically. Based on the quantitative crop model GECROS that interconnects various traits to crop productivity, we review natural variation in relevant traits, from biochemical aspects of leaf photosynthesis to morpho-physiological crop characteristics. While large phenotypic variations (sometimes &gt;2-fold) for leaf photosynthesis and its underlying biochemical parameters were reported, few quantitative trait loci (QTL) were identified, accounting for a small percentage of phenotypic variation. More QTL were reported for sink size (that feeds back on photosynthesis) or morpho-physiological traits (that affect canopy productivity and duration), together explaining a much greater percentage of their phenotypic variation. Traits for both photosynthetic rate and sustaining it during grain filling were strongly related to nitrogen-related traits. Much of the molecular basis of known photosynthesis QTL thus resides in genes controlling photosynthesis indirectly. Simulation using GECROS demonstrated the overwhelming importance of electron transport parameters, compared with the maximum Rubisco activity that largely determines the commonly studied light-saturated photosynthetic rate. Exploiting photosynthetic natural variation might significantly improve crop yield if nitrogen uptake, sink capacity, and other morpho-physiological traits are co-selected synergistically.