bluuebunny/crossref_metadata_2025_split huggingface dataset:
Machine-learning ready data on the thermal power consumption of the Mars Express Spacecraft
Authors: Petković Matej , Lucas Luke , Levatić Jurica , Breskvar Martin , Stepišnik Tomaž , Kostovska Ana , Panov Panče , Osojnik Aljaž , Boumghar Redouane , Martínez-Heras José A. , Godfrey James , Donati Alessandro , Džeroski Sašo , Simidjievski Nikola , Ženko Bernard , Kocev Dragi 
Published: May 2022

AbstractWe present six datasets containing telemetry data of the Mars Express Spacecraft (MEX), a spacecraft orbiting Mars operated by the European Space Agency. The data consisting of context data and thermal power consumption measurements, capture the status of the spacecraft over three Martian years, sampled at six different time resolutions that range from 1 min to 60 min. From a data analysis point-of-view, these data are challenging even for the more sophisticated state-of-the-art artificial intelligence methods. In particular, given the heterogeneity, complexity, and magnitude of the data, they can be employed in a variety of scenarios and analyzed through the prism of different machine learning tasks, such as multi-target regression, learning from data streams, anomaly detection, clustering, etc. Analyzing MEX’s telemetry data is critical for aiding very important decisions regarding the spacecraft’s status and operation, extracting novel knowledge, and monitoring the spacecraft’s health, but the data can also be used to benchmark artificial intelligence methods designed for a variety of tasks.
Using machine learning approaches to predict timely clinic attendance and the uptake of HIV/STI testing post clinic reminder messages
Authors: Xu Xianglong , Fairley Christopher K. , Chow Eric P. F. , Lee David , Aung Ei T. , Zhang Lei , Ong Jason J. 
Published: May 2022

AbstractTimely and regular testing for HIV and sexually transmitted infections (STI) is important for controlling HIV and STI (HIV/STI) among men who have sex with men (MSM). We established multiple machine learning models (e.g., logistic regression, lasso regression, ridge regression, elastic net regression, support vector machine, k-nearest neighbour, naïve bayes, random forest, gradient boosting machine, XGBoost, and multi-layer perceptron) to predict timely (i.e., within 30 days) clinic attendance and HIV/STI testing uptake after receiving a reminder message via short message service (SMS) or email). Our study used 3044 clinic consultations among MSM within 12 months after receiving an email or SMS reminder at the Melbourne Sexual Health Centre between April 11, 2019, and April 30, 2020. About 29.5% [899/3044] were timely clinic attendance post reminder messages, and 84.6% [761/899] had HIV/STI testing. The XGBoost model performed best in predicting timely clinic attendance [mean [SD] AUC 62.8% (3.2%); F1 score 70.8% (1.2%)]. The elastic net regression model performed best in predicting HIV/STI testing within 30 days [AUC 82.7% (6.3%); F1 score 85.3% (1.8%)]. The machine learning approach is helpful in predicting timely clinic attendance and HIV/STI re-testing. Our predictive models could be incorporated into clinic websites to inform sexual health care or follow-up service.
A population genetic analysis of the Critically Endangered Madagascar big-headed turtle, Erymnochelys madagascariensis across captive and wild populations
Authors: White Nina F. D. , Mennell Holly , Power Georgia , Edwards Dominic , Chrimes Luke , Woolaver Lance , Velosoa Juliette , Randriamahita  , Mozavelo Richard , Rafeliarisoa Tsilavo Hasina , Kuchling Gerald , Lopez Javier , Bekarany Ernest , Charles Namotoa , Young Richard , Lewis Richard , Bruford Michael W. , Orozco-terWengel Pablo 
Published: May 2022

AbstractErymnochelys madagascariensisis a Critically Endangered turtle endemic to Madagascar. Anthropogenic activity has depleted the wild population by 70% in the last century, and effective conservation management is essential to ensuring its persistence. Captive breeding was implemented to augment depleted populations in the southern part of Ankarafantsika National Park (ANP), when no genetic data were available forE. madagascariensis. It is unknown how much of the natural population’s diversity is encapsulated in captivity. We used eight microsatellite loci and fragments of two mitochondrial genes to identify the genetic structure ofE. madagascariensisin the wild. Captive bred turtles were compared with wild populations in order to assess the representativeness of this ex situ conservation strategy for ANP. Six microsatellite clusters, ten cytochrome b, and nine COI haplotypes were identified across wild populations, with high genetic divergence found between populations in two groups of watersheds. Captive bred individuals represent three out of six sampled microsatellite clusters found in the wild and just one mitochondrial haplotype, possibly due to genetic drift. To improve genetic representation, the strategy of frequent interchange between captive and wild breeders within ANP should be revitalised and, as originally planned, hatchlings or juveniles should not be released beyond ANP.
Energy and economic efficiency of climate-smart agriculture practices in a rice–wheat cropping system of India
Authors: Kakraliya S. K. , Jat H. S. , Singh Ishwar , Gora M. K. , Kakraliya Manish , Bijarniya Deepak , Sharma P. C. , Jat M. L. 
Published: May 2022

AbstractIntensive tillage operations, indiscriminate use of irrigation water, chemical fertilizers, and pesticides and crop biomass burning have made the conventional rice–wheat (RW) system highly energy-intensive and inefficient. In the recent past, portfolios of climate-smart agricultural practices (CSAP) have been promoted as a potential alternative to improve the energy efficiency in conventional RW system. Therefore, to evaluate the energy input–output relation, energy flow and economic efficiency in various combinations of crop management options, a 3-year (2014–2017) on-farm study was conducted at Karnal, India. Various portfolio of management practices; Sc1-Business as usual (BAU) or Conventional tillage (CT) without residue, Sc2-CT with residue, Sc3-Reduce tillage (RT) with residue + recommended dose of fertilizer (RDF), Sc4-RT/Zero tillage (ZT) with residue + RDF, Sc5-ZT with residue + RDF + GreenSeeker + Tensiometer, Sc6-Sc5 + Nutrient expert were investigated. Present study results revealed that net energy, energy use efficiency and energy productivity were 11–18, 31–51 and 29–53% higher under CSAP (mean of Sc4, Sc5 and Sc6) in RW system than Sc1, respectively. However, renewable and non-renewable energy inputs were 14 and 33% higher in Sc1 compared to CSAP (4028 and 49,547 MJ ha−1), respectively, it showed that BAU practices mostly dependents on non-renewable energy sources whereas CSAP dependents on renewable energy sources. Similarly, the adoption of CSAP improved the biomass yield, net farm income and economic efficiency by 6–9, 18–23 and 42–58%, respectively compared to Sc1. Overall, the adoption of CSAP could be a viable alternative for improving energy use efficiency, farm profitability and eco-efficiency in the RW system.
Iron oxide nanoflowers encapsulated in thermosensitive fluorescent liposomes for hyperthermia treatment of lung adenocarcinoma
Authors: Theodosiou Maria , Sakellis Elias , Boukos Nikos , Kusigerski Vladan , Kalska-Szostko Beata , Efthimiadou Eleni 
Published: May 2022

AbstractMagnetic hyperthermia (MHT) is in the spotlight of nanomedical research for the treatment of cancer employing magnetic iron oxide nanoparticles and their intrinsic capability for heat dissipation under an alternating magnetic field (AMF). Herein we focus on the synthesis of iron oxide nanoflowers (Nfs) of different sizes (15 and 35 nm) and coatings (bare, citrate, and Rhodamine B) while comparing their physicochemical and magnetothermal properties. We encapsulated colloidally stable citrate coated Nfs, of both sizes, in thermosensitive liposomes via extrusion, and RhB was loaded in the lipid bilayer. All formulations proved hemocompatible and cytocompatible. We found that 35 nm Nfs, at lower concentrations than 15 nm Nfs, served better as nanoheaters for magnetic hyperthermia applications. In vitro, magnetic hyperthermia results showed promising therapeutic and imaging potential for RhB loaded magnetoliposomes containing 35 nm Nfs against LLC and CULA cell lines of lung adenocarcinoma.
The superior beneficial effects of exercise training versus hormone replacement therapy on skeletal muscle of ovariectomized rats
Authors: Silva Sara Barros , Honorato-Sampaio Kinulpe , Costa Sabrina Paula , Domingues Talita Emanuela , da Cruz Timilly Mayra Martins , Rodrigues Cíntia Maria , Costa Karine Beatriz , dos Santos Jousielle Márcia , da Silva Lage Vanessa Kelly , Gaiad Thais Peixoto , Santos Ana Paula , Dias-Peixoto Marco Fabrício , Coimbra Cândido Celso , dos Reis Adelina Martha , Szawka Raphael Escorsim , Figueiredo Pedro Henrique Scheidt , Costa Henrique Silveira , Oliveira Murilo Xavier , Mendonça Vanessa Amaral , Lacerda Ana Cristina Rodrigues 
Published: May 2022

AbstractPrevious studies have highlighted the positive effects of Estradiol (E2) replacement therapy and physical exercise on skeletal muscle during menopause. However, the comparison effects of exercise training (ET) and estradiol replacement therapy during menopause on skeletal muscle have not been investigated to date. This study aimed to compare the effects of endurance exercise training versus E2 replacement therapy on mitochondrial density, redox status, and inflammatory biomarkers in the skeletal muscle of ovariectomized rats. Thirty female Wistar rats (12-week-old) were randomly assigned into three groups: Untrained ovariectomized rats (UN-OVX, n = 10); untrained ovariectomized rats treated with estradiol replacement therapy (E2-OVX); and, trained ovariectomized rats (TR-OVX). After ovariectomy, the E2-OVX rats were treated subcutaneously with E2 (implanted Silastic® capsule containing 360 μg of 17β-estradiol/mL) while the TR-OVX group performed an exercise training protocol (50–70% of maximal running speed on a treadmill, 60 min/day, 5 days/week for 8 weeks). After euthanasia, the soleus muscle was processed for histological and biochemical evaluations. Only exercise prevented the reduction of maximal oxygen consumption and increased mechanical efficiency (ME). While mitochondrial muscle density, total antioxidant capacity (FRAP), catalase (CAT) activity, and interleukin 10 levels were higher in TR-OVX, only OVX-E2 presented higher CAT activity and lower interleukin 6 levels. Endurance exercise training compared with E2 replacement therapy maintains the aerobic capacity improving the ME of OVX rats. In addition, only endurance exercise training raises the skeletal muscle mitochondrial content and tends to balance the redox and inflammatory status in the skeletal muscle of OVX rats.
Effect of high-level fine particulate matter and its interaction with meteorological factors on AECOPD in Shijiazhuang, China
Authors: Song Beibei , Zhang Huiran , Jiao Libin , Jing Zeng , Li Honglin , Wu Siyu 
Published: May 2022

AbstractEpidemiological evidence of the effect of high-level air pollution and its interaction with meteorological factors on the risk of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is limited. Daily data on AECOPD cases, air pollutants and meteorological factors were collected from 2015 to 2018 in Shijiazhuang. A distributed lag non-linear model (DLNM) was used to explore the lag and cumulative effect of PM2.5 on the risk of AECOPD. The effect of the interaction between PM2.5 and meteorological factors on AECOPD was estimated by a generalized additive model (GAM) and a stratification model. A total of 4766 patients with AECOPD were enrolled. After controlling for confounders, each 10 μg/m3 increase in PM2.5 led to a 5.8% increase in the risk of AECOPD on day lag 0. The cumulative effect of PM2.5 on AECOPD risk showed an increasing trend after 3 days. Similar results were observed in both smoking and non-smoking patients. There was an interaction between PM2.5 and meteorological factors, and the risk of AECOPD was higher in cold and lower humidity conditions than in other conditions. High-level PM2.5 exposure is positively associated with the risk of AECOPD onset, and the effect of PM2.5 can be modified by the temperature and relative humidity. Public health guidelines should pay close attention to AECOPD risk under the condition of high-level PM2.5 with low temperature or low humidity.
Controlling surface porosity of graphene-based printed aerogels
Authors: Zhou Binghan , Chen Zhuo , Cheng Qian , Xiao Mingfei , Bae Garam , Liang Dongfang , Hasan Tawfique 
Published: May 2022

AbstractThe surface porosity of graphene-based aerogels strongly influences their performance in applications involving mass transfer. However, the factors determining the surface porosities are not well-understood, hindering their application-specific optimisation. Here, through experiments and hydrodynamic simulations, we show that the high shear stress during the graphene-based aerogel fabrication process via 3D printing leads to a non-porous surface. Conversely, crosslinking of the sheets hinders flake alignment caused by shearing, resulting in a porous surface. Our findings enable fine control of surface porosity of printed graphene-oxide aerogels (GOA) through regulation of the crosslinking agents and shear stress. Using this strategy, we demonstrate the performance advantages of GOA with porous surface over their non-porous counterpart in dye adsorption, underscoring the importance of surface porosity in certain application scenarios.
Ecology and evolution of chlamydial symbionts of arthropods
Authors: Halter Tamara , Köstlbacher Stephan , Collingro Astrid , Sixt Barbara S , Tönshoff Elena R , Hendrickx Frederik , Kostanjšek Rok , Horn Matthias 
Published: May 2022

Abstract
The phylum Chlamydiae consists of obligate intracellular bacteria including major human pathogens and diverse environmental representatives. Here we investigated the Rhabdochlamydiaceae, which is predicted to be the largest and most diverse chlamydial family, with the few described members known to infect arthropod hosts. Using published 16 S rRNA gene sequence data we identified at least 388 genus-level lineages containing about 14 051 putative species within this family. We show that rhabdochlamydiae are mainly found in freshwater and soil environments, suggesting the existence of diverse, yet unknown hosts. Next, we used a comprehensive genome dataset including metagenome assembled genomes classified as members of the family Rhabdochlamydiaceae, and we added novel complete genome sequences of Rhabdochlamydia porcellionis infecting the woodlouse Porcellio scaber, and of ‘Candidatus R. oedothoracis’ associated with the linyphiid dwarf spider Oedothorax gibbosus. Comparative analysis of basic genome features and gene content with reference genomes of well-studied chlamydial families with known host ranges, namely Parachlamydiaceae (protist hosts) and Chlamydiaceae (human and other vertebrate hosts) suggested distinct niches for members of the Rhabdochlamydiaceae. We propose that members of the family represent intermediate stages of adaptation of chlamydiae from protists to vertebrate hosts. Within the genus Rhabdochlamydia, pronounced genome size reduction could be observed (1.49–1.93 Mb). The abundance and genomic distribution of transposases suggests transposable element expansion and subsequent gene inactivation as a mechanism of genome streamlining during adaptation to new hosts. This type of genome reduction has never been described before for any member of the phylum Chlamydiae. This study provides new insights into the molecular ecology, genomic diversity, and evolution of representatives of one of the most divergent chlamydial families.
Integrating multiple stubs in stepped‐impedance filter aiming for high selectivity
Authors: Sami Abdul , Gomez Laso Miguel Angel , Lopetegi Txema , Arnedo Israel , Calero Ibai , Teberio Fernando , Martin Iglesias Petronilo , Benito David , Arregui Ivan 
Published: May 2022

AbstractA design technique to include multiple and fully‐controlled transmission zeros (TZs) in the frequency response of rectangular waveguide commensurate‐line stepped‐impedance filters is presented in this letter. These bandpass filters (BPFs) are known for having reduced sensitivities against manufacturing inaccuracies and are composed of multiple waveguide sections. In order to improve their selectivity, 3λg/4 and λg/4‐stubs are included to create multiple TZs around the passband. The proposed technique allows us to add multiple stubs in a single section and, therefore, only minor adjustments in the affected part of the filter are required, which simplifies the overall design process. The technique has been verified with a design example with four TZs (two on each side) near the passband.
Plate augmentation and bone grafting in treatment of femoral shaft nonunion initially fixed by intramedullary nail
Authors: Mohamed Mohamed A. , Noaman Hassan H. , Soroor Yasser O. , Elsayed Moustafa 
Published: May 2022

Introduction: This study aims to evaluate the results of plate augmentation and bone grafting without removing the nail in the treatment of nonunited, nailed femoral shaft fractures.Methods: Twenty patients with atrophic nonunion femoral shaft fractures initially fixed by intramedullary nail were treated by augmentation plating and iliac bone graft with retention of the nail. Patients were evaluated at regular intervals using an X-ray and Wu scoring system, which assesses clinical and radiological signs of healing.Results: All 20 patients achieved bony union at a mean time of 4.9 months (3–8 months). According to Wu’s score, 12 cases showed excellent results, and 8 cases obtained good results with no complications recorded.Conclusion: augmentation plating and iliac bone graft provide a good and safe method of treatment of previously nailed and non-united femoral shaft fractures.Level of evidence: Level 4; Case Series.
Interstitial Laser Ablation of Feeding Vessels to a Large Placental Chorioangioma
Authors: Turgut Ezgi , Atalay Aysegul , Sakcak Bedri , Sahin Dilek 
Published: May 2022

AbstractBackground Chorioangioma is a vascular neoplasm of the placenta with the potential to cause heart failure, hydrops, and even death.Case A 30-year-old patient was referred owing to a large placental chorioangioma and fetal hydrops at 28 weeks of gestation. The patient underwent ultrasound-guided interstitial laser ablation. Ten days later, fetal blood transfusion was performed and at 31 weeks of gestation, and the patient delivered a female infant by cesarean section. The newborn was discharged from the neonatal intensive care unit without any complication.Conclusion According to our case, large placental chorioangioma may have a favorable outcome with interstitial laser ablation and fetal transfusion.
Management of Facial Second-Degree Burns with Nanocellulose-Based Dressing: A Case Series and Systematic Review
Authors: Ciudad Pedro , Escandón Joseph M. , Bravo Lilyan L. , Manrique Oscar J. 
Published: May 2022

AbstractPrevious studies have evaluated the effectiveness of bacterial nanocellulose (BNC) for the treatment of thermal injuries, but the synergic effect of platelet-rich plasma (PRP) with BNC-based dressing for burns still requires further investigation. Herein, we evaluated the effectiveness of BNC dressings in the management of facial burns using PRP. Patients with second-degree facial burns were treated with BNC-based wound dressings after debridement. The burn's depth and epithelialization were evaluated by clinical assessment. Besides using the dressings, we injected PRP subcutaneously into the left-hemifacial burns. The right hemiface was only treated with the dressings. Scar quality was assessed using the Patient and Observer Scar Assessment Scale (POSAS). Eight patients were included with superficial second-degree burns in 75% of the cases and deep second-degree burns in 25%. Overall, dressings were placed 3.25 days after the initial insult. None of the patients presented with complications after dressing placement. Dressing changes were not required, and no further surgical management was necessary. The mean time for epithelialization was 11.4 days. During subgroup analysis, we did not find a significant difference in the epithelialization time when comparing BNC-based dressings (11.8 days) to BNC-based dressings + PRP (11 days, p = 0.429). The mean POSAS scores from a patient (17 vs. 12.3, p = 0.242) and surgeon (13.5 vs. 11.3, p = 0.26) standpoint were not significantly different using BNC-based dressings versus BNC-based dressings + PRP. Nanocellulose-based dressings are effective to treat second-degree facial burns. It enhances reepithelialization with optimal esthetic outcomes with or without PRP.
Entrapment Neuropathies of the Shoulder
Authors: Alaia Erin F. , Day Michael S. , Alaia Michael J. 
Published: May 2022

AbstractEntrapment neuropathies of the shoulder most commonly involve the suprascapular or axillary nerves, and they primarily affect the younger, athletic patient population. The extremes of shoulder mobility required for competitive overhead athletes, particularly in the position of abduction and external rotation, place this cohort at particular risk. Anatomically, the suprascapular nerve is most prone to entrapment at the level of the suprascapular or spinoglenoid notch; the axillary nerve is most prone to entrapment as it traverses the confines of the quadrilateral space.Radiographs should be ordered as a primary imaging study to evaluate for obvious pathology occurring along the course of the nerves or for pathology predisposing the patient to nerve injury. Magnetic resonance imaging plays a role in not only identifying any mass-compressing lesion along the course of the nerve, but also in identifying muscle signal changes typical for denervation and/or fatty atrophy in the distribution of the involved nerve.
Technical Update on MR Neurography
Authors: Martín-Noguerol Teodoro , Montesinos Paula , Hassankhani Alvand , Bencardino Dario A. , Barousse Rafael , Luna Antonio 
Published: May 2022

AbstractImaging evaluation of peripheral nerves (PNs) is challenging. Magnetic resonance imaging (MRI) and ultrasonography are the modalities of choice in the imaging assessment of PNs. Both conventional MRI pulse sequences and advanced techniques have important roles. Routine MR sequences are the workhorse, with the main goal to provide superb anatomical definition and identify focal or diffuse nerve T2 signal abnormalities. Selective techniques, such as three-dimensional (3D) cranial nerve imaging (CRANI) or 3D NerveVIEW, allow for a more detailed evaluation of normal and pathologic states. These conventional pulse sequences have a limited role in the comprehensive assessment of pathophysiologic and ultrastructural abnormalities of PNs. Advanced functional MR neurography sequences, such as diffusion tensor imaging tractography or T2 mapping, provide useful and robust quantitative parameters that can be useful in the assessment of PNs on a microscopic level. This article offers an overview of various technical parameters, pulse sequences, and protocols available in the imaging of PNs and provides tips on avoiding potential pitfalls.