bluuebunny/crossref_metadata_2025_split huggingface dataset:
Charge Collection Dynamics of the ARCADIA Passive Pixel Arrays: Laser Characterization and TCAD Modeling
Authors: Corradino Thomas , Dalla Betta G.-F. , Neubüser C. , Pancheri L. 
Published: July 2022

Monolithic Active Pixel Sensors (MAPS) represent one of the most promising technologies for the next generation of radiation detectors. The ARCADIA project aims at the development of Fully Depleted (FD) MAPS employing a production process compatible with a 110 nm commercial CMOS technology. The first engineering run of the project included matrices of active pixels with embedded analog and digital frontend electronics and passive test structures such as passive pixel arrays, MOS capacitors and backside diodes. Although the produced samples were already characterized from the electrical point of view, a thorough study of the charge collection dynamics of the passive pixel arrays was still missing. In this paper we show the results of the dynamic characterization of a group of passive pixel arrays with different pixel pitches (50, 25 and 10 μm) and different pixel layouts. The tested samples have been illuminated from the backside with an infrared and a red laser with wavelengths equal to 1,060 nm and 660 nm, respectively. The pixel arrays have been mounted on a custom readout PCB connected to an external amplifier with 1 GHz bandwidth and the signals have been acquired through a fast digital oscilloscope. We employed both focused and unfocused laser spots to evaluate the change in the measured signal as a function of the laser spot position and the average response of the pixel arrays. An excellent agreement has been demonstrated by comparing the measured signals with the results of transient TCAD simulations and a time for 50% charge collection of 7.8, 4.2 and 2.6 ns has been predicted and experimentally validated in pixels with 50, 25 and 10 μm pitch, respectively.
Associations Between Child Maltreatment, Inflammation, and Comorbid Metabolic Syndrome to Depressed Mood in a Multiethnic Urban Population: The HELIUS Study
Authors: Willemen Fabienne E. M. , van Zuiden Mirjam , Zantvoord Jasper B. , de Rooij Susanne R. , van den Born Bert-Jan H. , Hak A. Elisabeth , Thomaes Kathleen , Segeren Menno , Elsenburg Leonie K. , Lok Anja 
Published: July 2022

BackgroundChild maltreatment is a common negative experience and has potential long-lasting adverse consequences for mental and physical health, including increased risk for major depressive disorder (MDD) and metabolic syndrome. In addition, child maltreatment may increase the risk for comorbid physical health conditions to psychiatric conditions, with inflammation as an important mediator linking child maltreatment to poor adult health. However, it remains unresolved whether experiencing child maltreatment increases the risk for the development of comorbid metabolic syndrome to MDD. Therefore, we investigated whether child maltreatment increased the risk for comorbid metabolic syndrome to depressed mood. Subsequently, we examined whether C-reactive protein (CRP), as an inflammatory marker, mediated this association. In addition, we investigated whether effects differed between men and women.MethodsAssociations were examined within cross-sectional data from the multiethnic HELIUS study (N = 21,617). Adult residents of Amsterdam, Netherlands, self-reported on child maltreatment (distinct and total number of types experienced before the age of 16 years) as well as current depressed mood (PHQ-9 score ≥ 10), and underwent physical examination to assess metabolic syndrome. The CRP levels were assessed in N = 5,998 participants. Logistic and linear regressions were applied for binary and continuous outcomes, respectively. All analyses were adjusted for relevant demographic, socioeconomic, and lifestyle characteristics, including ethnicity.ResultsA higher number of maltreatment types as well as distinct types of emotional neglect, emotional abuse, and sexual abuse were significantly associated with a higher risk for current depressed mood. Child maltreatment was not significantly associated with the risk for metabolic syndrome in the whole cohort, nor within individuals with depressed mood. As child maltreatment was not significantly associated with the CRP levels, subsequent mediation analyses were not performed. No significant moderating effects by sex were observed.ConclusionIn this multiethnic urban cohort, child maltreatment was associated with a higher risk for depressed mood. Contrary to our expectations, child maltreatment was not significantly associated with an increased risk for metabolic syndrome, neither in the whole cohort nor as a comorbid condition in individuals with depressed mood. As the data were cross-sectional and came from a non-clinical adult population, longitudinal perspectives in relation to various stages of the investigated conditions were needed with more comprehensive assessments of inflammatory markers.
Consumers' Knowledge, Attitudes, and Practices Toward Calorie Labeling in Riyadh City, Saudi Arabia: A Cross-Sectional Assessment
Authors: AlShehri Nouf M. , AlMarzooqi Mezna A. 
Published: July 2022

BackgroundMenu calorie labeling is a useful means to encourage consumers to be informed about healthy eating and food choices. It is projected as an innovative method that will change the food environment and increases consumers' awareness of calories.ObjectiveThis study aims to determine the consumer's knowledge, attitudes, and practices toward menu calorie labeling in Saudi Arabia.MethodsThis is a descriptive cross-sectional study involving 435 consumers in Saudi Arabia. The participants filled out an online electronic survey questionnaire that assesses the demographic factors, knowledge, attitudes, practices, and barriers toward menu calorie labeling. Logistic regression was performed to determine the predictor of attitudes of consumers toward menu calorie labeling.ResultsOf those 435 consumers, 50.1% were men, 33% were in the age group of 30–39, and 49.4% had a bachelor's degree. The majority of the participants reported that they can understand the calorie labels that were presented on the menus of the restaurants (N = 365, 83.9%). A high percentage of participants reported that calorie labeling encourages them to choose foods with a smaller number of calories (N = 387, 89%) and supported the posting of calorie content next to the price of the food items on the menus (N = 405, 93.1%). Barriers to using calorie labels were time-consuming and low-calorie food items are usually costly. Gender and educational attainment were found significantly associated with consumers' knowledge while marital status and BMI level were found significantly associated with attitudes and practices to using calorie labels (p &lt; 0.05).ConclusionOverall, the participants had adequate knowledge and positive attitudes about menu calorie labeling in Saudi Arabia. Menu calorie labeling may be a useful policy tool for promoting healthy eating habits and appropriate caloric consumption.
The Diagnostic Value of Mitochondrial Mass of Peripheral T Lymphocytes in Early Sepsis
Authors: Pang Ling-Xiao , Cai Wen-Wei , Chen Lue , Fu Jin , Xia Chun-Xiao , Li Jia-Yan , Li Qian 
Published: July 2022

BackgroundStudies have shown that lymphocyte dysfunction can occur during the early stages of sepsis and that cell dysfunction is associated with mitochondrial dysfunction. Therefore, quantifying the mitochondrial function of lymphocytes in patients with sepsis could be valuable for the early diagnosis of sepsis.MethodsSeventy-nine patients hospitalized from September 2020 to September 2021 with Sepsis-3 were retrospectively analyzed and subsequently compared with those without sepsis.ResultsUnivariate analysis showed statistical differences between the data of the two groups regarding age, neutrophil/lymphocyte, procalcitonin (PCT), C-reactive protein, total bilirubin, serum creatinine, type B natriuretic peptide, albumin, prothrombin time, activated partial thromboplastin time, lactic acid, single-cell mitochondrial mass (SCMM)-CD3, SCMM-CD4, SCMM-CD8, and Acute Physiology and Chronic Health Evaluation II score (P &lt; 0.05). Multivariate logistic regression analysis performed on the indicators mentioned above demonstrated a statistical difference in PCT, lactic acid, SCMM-CD4, and SCMM-CD8 levels between the two groups (P &lt; 0.05). The receiver operating characteristic curves of five models were subsequently compared [area under the curve: 0.740 (PCT) vs. 0.933 (SCMM-CD4) vs. 0.881 (SCMM-CD8) vs. 0.961 (PCT + SCMM-CD4) vs. 0.915 (PCT+SCMM-CD8), P &lt; 0.001].ConclusionSCMM-CD4 was shown to be a better diagnostic biomarker of early sepsis when compared with the traditional biomarker, PCT. Furthermore, the value of the combination of PCT and SCMM-CD4 in the diagnosis of early sepsis was better than that of SCMM-CD4 alone.
Polypoid arteriovenous malformation of the rectum: A case report
Authors: Krizzuk Dimitri , Cotesta Maria , Galiffa Giampaolo , Peluso Ilaria , Falbo Francesco , Biancucci Andrea , Puscio Sara , Michelotto Chiara , Pasecinic Carolina , Montalto Gioacchino Maria , Sammartino Francesco 
Published: July 2022

BackgroundIntestinal arteriovenous malformation is an abnormal connection between arteries and veins that bypasses the capillary system and may be a cause of significant lower gastrointestinal bleeding. On endoscopy, arteriovenous malformations are usually flat or elevated, bright red lesions. Overall, rectal localization of arteriovenous malformations is rare. The same may be said about polypoid shape arteriovenous malformations. Herein, we present a case of a large rectal polypoid arteriovenous malformations.MethodsClinical, diagnostic, and treatment modalities of the patient were reviewed. Pre- and post-operative parameters were collected and analyzed. The clinical English literature is also reviewed and discussedResultsA 60-year-old female patient was admitted to our emergency department for rectorrhagia and anemia. Rectoscopy revealed a polypoid lesion in the rectum and the biopsy showed fibrosis, necrosis areas, and hyperplastic glands. A total body contrast-enhanced computed tomography (CT) was performed revealing a parietal pseudonodular thickening with concentric growth and contrast enhancement, extending for about 53 mm. The mass wasn't removed endoscopically due to concentric growth, sessile implant, and submucosal nature. The patient underwent an uneventful laparoscopic anterior rectal resection. The postoperative hospitalization was free of complications. Histology showed the presence of a polypoid AVM composed of dilated arteries, veins, capillaries, and lymphatics, engaging the submucosa, muscularis, and subserosa layer.ConclusionAfter a review of the current English literature, we found only one case of rectal polypoid AVM. The scarcity of documented cases encumbers optimal diagnostic and treatment approaches.
Changes in Gallbladder Contractile Function and its Influencing Factors After Minimally Invasive Gallbladder-Preserving Surgery for Cholecystitis With Incarcerated Gallstones
Authors: Ai Xiang-Nan , Wang Teng-Fei , Zhang Qiang , Ouyang Cai-Guo , Wu Zhen-Yu 
Published: July 2022

BackgroundCholecystitis with incarcerated gallstones (CIG) is a type of acute abdomen in the field of hepatobiliary surgery. Whether gallbladder-preserving surgery (GPS) can be performed to treat it, however, depends on the improvement of gallbladder contractile function. The present study aimed to investigate the changes in gallbladder contractile function and its influencing factors after minimally invasive GPS for CIG.MethodsA total of 95 patients with CIG treated in the Aerospace Center Hospital between May 2017 and May 2019 were enrolled as the study subjects. All patients received minimally invasive GPS. The patients' operation-related conditions (including stone removal success rate, duration of surgery, intraoperative blood loss, etc.), changes in gallbladder contractile function, and influencing factors of GPS were analyzed.ResultsAmong the 95 patients included in the study, the success rate of stone removal was 100%, the duration of surgery was 76.0 ± 26.5 min, and the intraoperative blood loss was 10.17 ± 4.43 ml. The rate of good gallbladder contractile function at one and two years after surgery was significantly higher than before surgery (P &lt; 0.05). Age, duration of surgery, stone recurrence, and diabetes were the independent risk factors for postoperative gallbladder contractile function (P &lt; 0.05).ConclusionMinimally invasive GPS for patients with CIG has a good curative effect. The changes in gallbladder contractile function after the surgery are influenced by many factors.
Exploring the scope of 4sb and 12a lymph node dissection for cT2-4 lower third gastric cancer: Study protocol for a prospective cohort trial
Authors: Zhang Haiqiao , Zheng Zhi , Liu Xiaoye , Cai Jun , Yin Jie , Zhang Jun 
Published: July 2022

BackgroundCurrently, the extent of 4sb and 12a lymph node dissection is not clear and is based on the personal understanding of the surgeon. It may result in damage to the splenic artery and portal vein, leading to surgical complications. Therefore, this study aims to explore the scope of 4sb and 12a lymph node dissection in cT2-4 lower third gastric cancer.MethodsThis is an ongoing prospective cohort trial. The total sample size required for the trial (March 2022 to February 2025) is approximately 524 patients. The participants are divided into the experimental (4sb first branch and 12a anterior lymphadenectomy) or control groups (traditional 4sb and 12a lymphadenectomy). Electronic data capture systems will be used to collect demographic, laboratory test, auxiliary examination, operation, postoperative condition, postoperative pathology, and follow-up data. The primary outcome is the 12a lymph node metastatic rate. Secondary outcomes include the pathology (consisting of the 4sb lymph node metastatic rate, the number of 4sb lymph nodes dissected, the number of 12a lymph nodes dissected and tumor pathological staging), a safety evaluation index (consisting of complications and mortality ≤30 days after surgery), an efficacy evaluation (consisting of operation data and postoperative recovery status), and follow-up data (consisting of 3-year or 5-year disease-free survival and overall survival).DiscussionBy exploring the scope of 4sb and 12a lymph node dissection on the premise of ensuring radical cure of the tumor, the operation is simplified, the operation time is shortened, the damage of important blood vessels is reduced, the intraoperative and postoperative complications are reduced, and the patient recovers as soon as possible. Our study is a prospective exploration of the pathology, safety, efficacy, and prognosis of the new and traditional methods of 4sb and 12a lymph node dissection.Trial registrationChinese Clinical Trial Registry, ChiCTR2200057698 (registration date: March 15, 2022).
Pertumbuhan Rohani Berdasarkan 1 Petrus 2:1-4 dan Aplikasinya dalam Kehidupan Orang Percaya
Authors: Santo Joseph Christ , Arifianto Yonatan Alex 
Published: July 2022

Dalam Kekristenan, pertumbuhan rohani menjadi prioritas para pemimpin gereja orang percaya maupun para pelayan. Pertumbuhan rohani tidak lepas dari tantangan, dan hal itu merupakan ujian kualitas iman dalam menghadapi tantangan. Harapan dari pertumbuhan rohani adalah orang Kristen yang dengan imannya mampu menghadapi dan mengatasi tantangan yang dihadapi. Tujuan penelitian ini adalah mendeskripsikan pertumbuhan rohani berdasarkan 1 Petrus 2:1-4, dan harapan yang dapat dicapai bila pertumbuhan rohani iman Kristen ini diaplikasikan dalam hidup orang percaya. Peneliti menggunakan metode penelitian pustaka dengan pendekatan kualitatif deskriptif. Kesimpulan dari penelitian ini adalah bahwa orang-orang percaya dan pemimpin gereja harus memahami bahwa indikasi pertumbuhan rohani berdasarkan surat 1 Petrus 2:1-4 adalah hidup dalam kesucian, rasa haus dan lapar akan firman Tuhan, dan hidup bergantung kepada Tuhan dalam persekutuan. Agar pertumbuhan rohani teraplikasi dalam kehidupan orang percaya diperlukan keterlibatan gembala dan warga jemaat sebagai pengajar pertumbuhan rohani.
La mediación en el aprendizaje humano. Una aproximación conceptual: la mediación cultural del patrimonio en las aulas
Authors: Sánchez Crisóstomo Nancy 
Published: July 2022

El presente artículo describe y analiza las concepciones en las que se fundamenta la mediación en el aprendizaje humano y su implicancia en el ámbito de la educación, para así promover la comprensión de esta temática desde el punto de vista psicológico, pedagógico o educativo, y que a partir de esta comprensión se brinde, con especial énfasis a los docentes, las bases teóricas que afiancen sus prácticas educativas, fundamenten sus actuaciones y fortalezcan sus conocimientos pedagógicos. Todo esto a través de los aportes de tres importantes estudiosos y autores contemporáneos que se han ocupado de la mediación para el proceso de aprender y de esta en el ámbito educativo; aportes que se encuentran contenidos en revistas científicas y de investigación indexadas en repositorios, aparecidos entre 1997 hasta la actualidad.
A pesar de la existencia de una diversidad de información sobre la mediación desde diferentes perspectivas, son pocos los artículos que exploran de manera descriptiva y con ejemplos los fundamentos que sostienen las diversas concepciones de la mediación del aprendizaje y su implicancia en el campo de la educación, así como las maneras de actuar o acciones docentes que fomenten su práctica.
Rancang Bangun Sistem Informasi Pemesanan Paket Wisata Berbasis Web (Studi Kasus pada Jams Tour)
Authors: Sutanto Prasojo Herdy , Lidwan Nanang , Ridwan Wawan , Lahat Mohamad Amas , Al Atas M. Mahdi 
Published: July 2022

<p>Abstrak. Jams Tour adalah sebuah biro jasa tour yang masih memproses pemesanan paket wisata bagi konsumen melalui telepon atau melalui kunjungan langsung ke perusahaan, memperkenalkan paket wisata melalui brosur kertas dan spanduk, dan mencatata kegiatan administrasi menggunakan media kertas. Dengan proses transaksi tradisional, terjadi kesalahan penjadwalan paket tour yang dipesan, kesulitan dalam temu kembali data sehingga berdampak pada meruginya perusahaan. Untuk meningkatkan kinerja manajemen prusahaan, dipandang perlu mengembangkan sistem transaksi pemesanan yang menggunakan teknologi komputer secara menyeluruh. Papert ini menyajikan rancangan sistem informasi tour berbasis web sebagai solusi yang lebih efektive dan efisien. Pengembangan sistem melalui beberapa tahapan yang mencakup analisis kebutuhan, pembuatan model berbasis UML, pemrograman berbasis WEB yaitu PHP dan database MySql, serta Pengujian Black Box dan Alpha. Model sistem yang dikembangkan dapat mencegah kesalahan transaksi data pesanan, dapat memantau informasi pelanggan dan memudahkan untuk pencarian data juga promosi paket wisata yang baru. Kata kunci: Travel, Paket Wisata, Sistem Informasi Berbasis Web <br /> <br />Abstract. Jams Tour is a tour service agency that still processes tour package bookings for consumers via telephone or direct visits to companies, introduces tour packages through paper brochures and banners, and records administrative activities using paper media. With the traditional transaction process, there was an error scheduling the tour package that was booked, difficulties in data retrieval, which resulted in losses for the company. To improve company management performance, it is deemed necessary to develop an order transaction system that uses computer technology as a whole. This Papert presents a web-based tour information system design as a more effective and efficient solution. System development in several stages including needs analysis, UML-based modeling, WEB-based programming, namely PHP and MySql databases, and Black Box and Alpha testing. The model system developed can prevent order data transaction errors, can access customer information and make it easier to find data as well as promote new tour packages. Keywords: Travel, Tour Packages, Web-Based Information Systems</p>
Model Sistem Informasi Penyandang Masalah Sosial Yang Tidak Terjangkau (Studi Kasus: Dinas Sosial Provinsi Dki Jakarta)
Authors: Andiani Andiani , Saputri Nadya Paramitha 
Published: July 2022

<p><em>The existing social welfare problems have not yet been fully resolved, indicated by the fact that there are still people with social problems (beggars, homeless people, and neglected people) who have not been properly recorded. Seeing these problems, the DKI Jakarta Social Service needs to examine using a brief case study regarding people with social problems who have not been reached. Through reports provided by service officers, supervision, and social control when conducting socialization, by utilizing integrated smartphone technology. The method used in building the system is the prototype method, starting from requirements analysis, prototype making, system design, system coding, testing, and system evaluation. The output of the mobile-based application in the form of map and camera features with reports will be received by the DKI Jakarta Social Service on a web-based system.</em></p><p><em>Keywords: Information System, People with Social Problems, Web-Based</em></p><p> </p><p>ABSTRAK. Masalah kesejahteraan sosial yang ada hingga saat ini belum dapat sepenuhnya diselesaikan, ditandai dengan masih terdapat penyandang masalah sosial (pengemis, gelandangan, dan orang terlantar) yang belum terdata dengan baik. Melihat permasalahan tersebut, Dinas Sosial DKI Jakarta perlu mengkaji dengan menggunakan studi kasus singkat mengenai penyandang masalah sosial yang belum terjangkau. Melalui laporan yang diberikan petugas pelayanan, pengawasan, dan pengendalian sosia (P3S) saat melakukan sosialisasi, dengan memanfaatkan teknologi smartphone terintegrasi. Metode yang digunakan dalam membangun sistem adalah metode prototipe, dimulai dari analisis kebutuhan, pembuatan prototipe, perancangan sistem, pengkodean sistem, pengujian, serta evaluasi sistem. Luaran aplikasi berbasis mobile berupa fitur peta dan kamera dengan laporan akan diterima oleh Dinas Sosial DKI Jakarta pada sistem berbasis web.</p><p>Kata kunci: Sistem Informasi, Penyandang Masalah Sosial, Berbasis Web</p>