bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tecnossocialidade na pandemia de covid-19 e promoção da saúde de usuários e famílias: scoping review
Authors: Silva Tamires Carolina , Nascimento Leila Cristine do , Silva Bruna Moreira da , Tafner Daniela Priscila Oliveira do Vale , Potrich Tassiana , Viegas Selma Maria da Fonseca 
Published: April 2022

Objetivo: mapear as evidências científicas sobre a tecnossocialidade em tempos da pandemia de COVID-19 e a promoção da saúde para usuários/famílias da Atenção Primária à Saúde. Método: scoping review que utilizou a estratégia Participants, Concept e Context (PCC). A busca foi efetuada em seis bases de dados. Os achados foram extraídos, analisados e sintetizados de forma narrativa. Resultados: recuperou-se um total de 30.377 estudos; desses, 28 foram selecionados para a revisão. Os usuários encontram-se mais conectados em redes sociais, a fim de buscar informações sobre a COVID-19, sendo inquestionável a influência das mídias sociais no comportamento dos indivíduos. Conclusão: as redes sociais constituem terreno fértil para o compartilhamento de notícias e podem ser usadas por profissionais da saúde para a promoção da saúde em meio à pandemia de COVID-19. Além disso, o telessaúde desponta como importante ferramenta para a continuação do cuidado em tempos de isolamento social.
Deporte, cuerpo y alimentación: un análisis sociohistórico de cuatro generaciones de deportistas
Authors: Sánchez Sánchez Sandra , Parrilla Fernández José Manuel , Díaz Méndez Cecilia 
Published: April 2022

En este trabajo se estudia la interacción entre el deporte, las prácticas alimentarias y el control del cuerpo en mujeres deportistas españolas de cuatro generaciones y en cada una de ellas se diferencian tres grados de intensidad deportiva, desde las profesionales hasta las amateurs. Se emplea un enfoque socio-histórico, que permite ver el proceso de construcción social del cuerpo, desde las deportistas de la postguerra civil, momento en que la actividad deportiva es vivida por las mujeres como actividad lúdica y rodeada de carencias alimentarias, a la actualidad, donde la búsqueda del rendimiento ha modificado los patrones dietéticos para alcanzar metas deportivas. También se visibiliza la forma en que las practicas alimentarias, el control corporal y las normas deportivas se integran en la vida cotidiana de las mujeres, aún sin ser deportistas profesionales. Este trabajo, realizado a través de investigación cualitativa con entrevistas en profundidad, muestra cómo se han alterado las prácticas deportivas, alimentarias y corporales a lo largo del tiempo, así como sus determinantes, que se modifican generacionalmente. Si en la primera generación el contexto material es el que determinaba las prácticas, durante la etapa de plena modernización, se invierte la situación. A medida que la dimensión deportiva cobra protagonismo y se integra en las practicas cotidianas de las mujeres, se observa cómo se modifican los procesos de construcción corporal que van acompañados de cambios en los comportamientos deportivos y alimentarios.
In this work, the interaction between sport, eating practices, and body control are studied in four-generation Spanish female athletes, in all of them, three degrees of sport intensity are distinguished, from professional to amateur. A socio-historical approach is used, which allows us to see the process of the social construction of the body, since the post-civil war, when sports activity is experienced by women as a leisure activity and surrounded by food deficiencies, to today, where the performance has modified dietary patterns to achieve sports goals. It will also make visible the way in which dietary practices, body control, and sports norms are integrated into the daily life of women, even without being professional athletes. This work, carried out through qualitative research with in-depth interviews, shows how sports, food and body practices have altered over time, as well as their determinants, which are modified generationally. If in the first generation the material context is the one that determined the practices, during the stage of modernization, the situation is reversed. As the sports dimension takes centre stage and is integrated into the daily practices of women, it is observed how the processes of body construction are modified that are accompanied by changes in sports and eating behaviours.
Narrative Development Later in Life
Authors: Randall William L. , Khurshid Khurram N. 
Published: April 2022

Prevailing paradigms in gerontology tend to eclipse the creative side of aging, implicitly perceiving it in terms of a narrative of decline. Building on insights from the field of narrative gerontology, this paper proposes an explicitlyliterary metaphor for understanding the subjective experience of aging, one in which our lives themselves are conceived in textual terms: As novels we are continually composing––as author, narrator, protagonist, and reader more or less at once. Drawing on literary theorist Mikhail Bahktin, the paper argues the merits of the metaphor of life-as-novel, notes the entailments it carries with it, and enlists it to deepen our understanding of narrative development in later life, with special emphasis on the challenges such development can face. The paper concludes by discussing the implications of a “novel perspective” for the practice of narrative care with older adults and for future research into the poetics of growing old.
Analysing the Growth Prospects of Agribusiness Input Sector in India
Authors: Kumar Darsi Pradeep , Ashok K. R. , Karthikeyan C. , Olive P. Flowrine 
Published: April 2022

Aim: Agribusiness is undergoing huge transformation. Seed, fertilizer and pesticide sector plays a vital role in agribusiness. The aim of this paper is to study about the overview of agribusiness system in Indian and to analyze the growth prospects for agribusiness in India.
Study Design: Secondary data was collected from various government websites and reports. The data was organized and analysed to fulfil the objective of the study.
Methodology: Compounded Annual Growth Rate (CAGR) was used to analyse the data. Secondary data was collected from 2010 to 2020.
Results: Results revealed that the production, sale and consumption of major agricultural input-based agribusiness are growing with a CAGR of 2 per cent on an average. This revealed the scope for input-based agribusiness in India.
The Supply Chain Optimization of Ready Mix Concrete at PT X in Surabaya Using the Metaheuristic Method
Authors: Kresnadi Daniel Mulyono , Prayogo Doddy 
Published: April 2022

Infrastructure development is followed by an increase in demand for ready-mix concrete (RMC). Some failures in delivering RMC on time would delay construction performance or the truck would need to wait at the construction site, so the delivered concrete became useless if it exceeded the concrete setting time limit. This research optimizes the supply chain of ready mix concrete based on real-time data from a batching plant in Surabaya by using the metaheuristic method. The metaheuristic method used in this research are Particle Swarm Optimization (PSO) and Symbiotic Organisms Search (SOS), and also compares the performance of both metaheuristic algorithms, because both algorithms have proven effective in solving various optimization problems. The objective function of this research is to minimize the total waiting times of mixer trucks. The results showed that the SOS algorithm has better performance than the PSO algorithm, which gets lower total waiting times of 100,863 hours.
A 3D star shot to determine the gantry, collimator, and couch axes positions
Authors: Corns Robert , Yang Kaida , Ross Mason , Bhandari Shiva , Aryal Makunda , Ciaccio Peter 
Published: April 2022

AbstractA linear accelerator has three independent axes that are nominally intersecting at the isocenter. Modern treatment techniques require the coincidence of these axes to lie within a 1‐mm diameter sphere. A solution to verify this requirement is to wrap a film on a cylindrical surface, align the cylinder to the linac's isocenter and gantry axis, and take multiple exposures of slits, rotating either the gantry, collimator, or couch between exposures. The resulting exposure pattern is the 3D equivalent of the 2D star shot and encodes sufficient information to determine each axis’ position in 3D. Moreover, this method uses a single sheet 8“x10” film, a standard film scanner, and a phantom that can be readily built in‐house, making a practical solution to this 3D‐measurement problem.
Ultraviolet Narrowband Photomultiplication Type Organic Photodetectors with Fabry−Pérot Resonator Architecture
Authors: Zhao Zijin , Xu Chunyu , Ma Yao , Yang Kaixuan , Liu Ming , Zhu Xixiang , Zhou Zhengji , Shen Liang , Yuan Guangcai , Zhang Fujun 
Published: April 2022

AbstractUltraviolet (UV) narrowband photodetectors play a critical role in missile detection, flame monitoring, optical communication, etc. It is a great challenge to realize UV narrowband organic photodetectors due to wide photo‐harvesting property of organic materials, especially for photomultiplication type organic photodetectors (PM‐OPDs). In this work, a smart strategy is proposed to achieve UV narrowband response by coupling Fabry−Pérot microcavity with PM‐OPDs. PM‐OPDs are realized by using poly(3‐hexylthiophene‐2,5‐diyl):[6,6]‐phenyl‐C71‐butyric acid methyl ester (100:1, w/w) as active layers, exhibiting broadband response range covering from UV–vis region. Series of optical microcavities consisting of Ag/LiF/Ag with UV spectral selectivity are prepared, which are employed to couple with the PM‐OPDs for achieving UV narrowband response. The UV spectral selectivity of optical microcavity can be optimized by tuning the thickness of spacer layer and mirror layers, which can further regulate the photogenerated electron distribution near Al electrode to optimize the external quantum efficiency (EQE) spectra of the PM‐OPDs coupled with optical microcavity. The optimized PM‐OPDs coupled with optical microcavity exhibit EQE of 9300% at 350 nm and narrowband response with 33 nm full‐width at half‐maximum under −15 V bias. This work indicates that PM‐OPDs coupled with optical microcavity should be an efficient strategy for achieving UV narrowband response.
Selectively Tunable Luminescence of Perovskite Nanocrystals Embedded in Polymer Matrix Allows Direct Laser Patterning
Authors: Martin Chantal , Prudnikau Anatol , Orazi Leonardo , Gaponik Nikolai , Lesnyak Vladimir 
Published: April 2022

AbstractCesium lead halide perovskite nanocrystals (NCs) have gained enormous attention as promising light‐emitting and light‐converting materials. Most of their applications require embedding NCs in various matrices, which is a challenging task due to their low stability, especially in the case of red‐emitting CsPbI3 NCs. In this work, a new approach is proposed allowing the formation of red‐emitting perovskite NCs by anion exchange induced directly inside a solid polymer matrix using green‐emitting CsPbBr3 NCs as templates and iodododecane as an iodine source. Moreover, a simple and efficient route to photo‐assisted termination of the anion exchange reaction in the polymer composite after reaching desired optical properties is demonstrated. The findings allow the authors to pattern a thin composite film with an ultrashort UV laser resulting in a selective generation of green‐ and red‐emitting features with a 15 µm resolution.
Diarylprolinol with Trifluoromethyl Substituents and Diphenylprolinol‐Derived Perfluoroalkanesulfonamide as Organocatalysts in the Cross‐Aldol Reaction of Aldehydes
Authors: Hayashi Yujiro , Tomikawa Masashi , Mori Naoki 
Published: April 2022

AbstractThe asymmetric cross‐aldol reaction of two different aldehydes is a synthetically relevant reaction. Diarylprolinol catalyst with trifluoromethyl substituents and sulfonamide catalyst derived from diphenylprolinol are organocatalysts for the cross‐aldol reaction. The reactivity and stereoselectivity of these two catalysts were compared in the asymmetric cross‐aldol reactions of propanal and acetaldehyde as nucleophilic aldehydes and several electrophilic aldehydes. Depending on the electrophilic aldehydes, the preferable catalyst differs. By the proper selection of these two catalysts, potentially synthetically useful chiral building blocks can be synthesized with diastereoselectivities of anti:syn=2.6:1∼>20:1 and enantioselectivities of 60∼>98% ee.magnified image
3D Conformal Fabrication of Piezoceramic Films
Authors: Liu Shiyuan , Shan Yao , Hong Ying , Jin Yuankai , Lin Weikang , Zhang Zhuomin , Xu Xiaote , Wang Zuankai , Yang Zhengbao 
Published: April 2022

AbstractPiezoceramic films are an essential class of energy‐conversion materials that have been widely used in the electronics industry. Although current methods create a great freedom for fabricating high‐quality piezoceramic films, it requires well‐controlled synthesis conditions, including special high‐cost equipment and planar substrates particularly. The limited substrate selections hinder the applications of piezoceramic films in 3D conformal structures where most objects possess complex curvilinear surfaces. To overcome such limitations, a fast, energy‐efficient, and cost‐effective approach, named flame treated spray (FTS) coating, is developed for preparing piezoceramic films on free‐form surfaces. The flame treatment significantly enhances the hydrophilicity of a substrate, assisting in forming a uniform and continuous thin film. The followed spray coating deposits hundreds of nanometers to several micrometers thick films on 3D free‐form surfaces. Given the size controllability and arbitrary surface compatibility of the FTS method, a highly conformal piezoelectric tactile sensor array (4 × 4) is assembled on a spherical surface for mimicking robot fingers and an on‐site thin‐film sensor on the wing of an aircraft model to monitor the vibration in real‐time during flight. The FTS film deposition offers a highly promising methodology for the application of functional thin‐film from micro‐ to marcoscale devices, regardless of conformal problems.
A Facile Three‐Component Catalyst‐Free Strategy: Synthesis of Indeno[1,2‐b][1,6]naphthyridine‐1,10(2H)‐dione Derivatives in Water
Authors: Li Chunmei , Zhang Furen , Li Tianci , Liu Zhiyuan , Shen Zhenlu 
Published: April 2022

AbstractA catalyst‐free protocol for synthesizing a new series of indeno[1,2‐b][1,6]naphthyridine‐1,10(2H)‐dione derivatives with good to excellent yields was established based on microwave‐assisted domino reaction of 4‐aminopyridin‐2(1H)‐ones, aldehydes and 1H‐indene‐1,3(2H)‐dione in water. The present approach exhibited useful and green features, such as water as reaction solvent, catalyst‐ and additive‐ free, short reaction time (20–30 min), as well as ease of desired products separation and purification without the need for column chromatography. Also to note, up to four new bonds were formed accompanied by generating water as sole by‐product in this one‐pot procedure.
Outcomes of endoscopic endonasal resection of pediatric craniopharyngiomas
Authors: Patel Tapan D. , Rullan‐Oliver Bianca , Ungerer Heather , Storm Phillip B. , Kohanski Michael A. , Adappa Nithin D. , Palmer James N. 
Published: April 2022

AbstractBackgroundCraniopharyngiomas have traditionally been treated via open transcranial approaches. More recent, endoscopic endonasal approaches have been increasingly used; however, there has been limited evaluation of long‐term outcomes for this approach.MethodsA retrospective review was performed to analyze patients with pediatric craniopharyngioma undergoing endonasal endoscopic resection from 2012 to 2020. Demographic information, clinicopathologic factors, and outcomes including follow‐up and recurrences were analyzed.ResultsAll 42 patients, with a mean age of 8.0 years, were included. The median follow‐up time was 49 months. Mean tumor diameter was 3.6 cm. All of the tumors had sellar and suprasellar components. The most common presenting symptoms were headaches (64.3%), visual changes (59.5%), and nausea/vomiting (38.1%). Most patients (73.3%) had resolution of their presenting symptoms by their first postoperative visit. Vision improved or remained normal in 69.0% of patients. Postoperatively, incidence of panhypopituitarism or diabetes insipidus developed in 89.7% and 77.8% of patients, respectively. The postoperative cerebrospinal fluid leak rate was 7.1%. The recurrence rate was 9.5%.ConclusionEndoscopic endonasal resection for pediatric craniopharyngiomas can achieve high rates of resection with low rates of disease recurrence when compared with the outcomes of open transcranial resection reported in the literature. However, hypothalamic‐pituitary dysfunction remains a significant postoperative morbidity in both approaches.
Regio‐ und stereoselektive Epoxidierung und saure Epoxidöffnung der antibakteriellen und antiplasmodischen Chlorotonile ergeben hochpotente Derivate
Authors: Hofer Walter , Oueis Emilia , Fayad Antoine Abou , Deschner Felix , Andreas Anastasia , de Carvalho Laìs Pessanha , Hüttel Stephan , Bernecker Steffen , Pätzold Linda , Morgenstern Bernd , Zaburannyi Nestor , Bischoff Markus , Stadler Marc , Held Jana , Herrmann Jennifer , Müller Rolf 
Published: April 2022

AbstractDie Zunahme von antimikrobiellen Resistenzen stellt eine ernsthafte Bedrohung für die öffentliche Gesundheit dar. Der Naturstoff Chlorotonil wurde als neues Antibiotikum identifiziert, das gegen multiresistente Gram‐positive Pathogene und Plasmodium falciparum wirkt. Obwohl Chlorotonil vielversprechende Aktivitäten zeigt, ist das Substanzgerüst hoch lipophil und weist mögliche biologische Labilitäten auf. Deshalb bemühten wir uns um Semisynthesen, um die pharmazeutischen Eigenschaften zu verbessern. Wir konnten die stereoselektive Epoxidierung und Epoxidringöffnung mit moderaten bis guten Ausbeuten demonstrieren, wobei Derivative mit signifikant erhöhter Löslichkeit erhalten wurden. Weiterhin wurde die in vivo‐Stabilität der Derivate verbessert, während deren nanomolare Aktivität gegen wichtige Humanpathogene (z. B. Methicillin‐resistente Staphylococcus aureus und P. falciparum) beibehalten wurde. Wir konnten weiterhin ausgezeichnete Aktivität des Wirkstoffkandidaten in einem murinen S. aureus‐Infektionsmodel zeigen.
Bio‐polymer modified nanoclay embedded forward osmosis membranes with enhanced desalination performance
Authors: Mamah Stanley Chinedu , Goh Pei Sean , Ismail Ahmad Fauzi , Yogarathinam Lukka Thuyavan , Suzaimi Nur Diyana , Opia Anthony Chukwunonso , Ojo Samuel , Ngwana Ngouangna Eugene 
Published: April 2022

AbstractThe substrate of forward osmosis (FO) thin‐film composite (TFC) membranes supports the formation of the selective layer. It can remarkably influence the structure as well as the physiochemical characteristics of the selective layer formed atop. Therefore, the improvement of TFC substrates in terms of its thickness, tortuosity and porosity can further fine tune the properties of the resultant TFC membranes. In this present study, TFC membrane comprising of polyamide selective layer and palygorskite‐chitin (PAL‐CH) containing polysulfone substrate was developed for FO desalination. The effects of PAL‐CH on the surface and structural properties of the substrate were examined. The FO desalination performance of the resultant membranes was evaluated in both active‐layer facing feed solution and active‐layer facing draw solution modes using NaCl as draw solution. In comparison with the un‐modified membrane, the TFC membrane with PAL‐CH embedded polysulfone substrate exhibited enhanced water flux and lower structural parameter. The incorporation of PAL‐CH hybrid nanomaterial resulted in improved flux of 34.39 L/m2 h1, which corresponds to improvement by 110% compared to that of pristine membranes. During the antifouling test, PAL‐CH‐S/PA membrane attained 97% water recovery while the pristine membrane attained 90% water recovery.
Design, synthesis, SAR, and biological evaluation of saccharin‐based hybrids as carbonic anhydrase inhibitors
Authors: Chinchilli Krishna K. , Royyala Venkata N. , Thacker Pavitra S. , Angeli Andrea , Danaboina Srikanth , Singh Priti , Nanduri Srinivas , Supuran Claudiu T. , Arifuddin Mohammed 
Published: April 2022

AbstractSaccharin is a cyclic secondary sulfonamide, which is a selective inhibitor of the tumor‐associated carbonic anhydrase (CA; EC 4.2.1.1) enzymes CA IX and CA XII compared to many primary sulfonamides. In this study, new saccharin‐1,2,3‐triazole and saccharin‐1,2,4‐oxadiazole hybrids were synthesized. All the newly synthesized molecules were screened for their CA‐inhibitory activity against four important human CA (hCA) isoforms: hCA I, hCA II, hCA IX, and hCA XII. Compounds 8a and 8f emerged as potent hCA II inhibitors (Ki = 3 µM). Compounds 6d, 6e and 7a, 7b were highly selective against hCA IX (6d, 6e) and hCA II (7a, 7b), with moderate inhibitory activity. The activity of these compounds was further confirmed by performing in silico docking studies against hCA II and hCA IX.
Hydrogen Peroxide‐triggered Chemical Strategy for Controlling CRISPR systems
Authors: Ji Huimin , Xiong Wei , Zhang Kaisong , Tian Tian , Zhou Xiang 
Published: April 2022

AbstractThe function of the CRISPR system can be conditionally controlled through rationally guided RNA engineering such that the target sequences can be precisely selected and manipulated. In particular, gRNA, as an important component of the CRISPR system, provides a unique tool for multifunctional control of the system based on the structure of the RNA itself. Therefore, we introduced here a protective group on the 2′‐OH position of RNA to inhibit RNA‐guided nucleic acid cleavage. Next, the modified gRNA can restore its original function under the chemical stimulation of hydrogen peroxide to realize the control of the CRISPR system. The experiment result demonstrated that the operating mechanism of this strategy may be based on chemical modifications that reduce the number of complementary base pairs between RNAs and targets, and the RNA‐protein interaction. This further enriches the toolbox of conditional control of CRISPR function and has broad potential for gene editing in living cells and disease treatment using endogenous hydrogen peroxide.
In Vivo Functional Ultrasound (fUS) Real‐Time Imaging and Dosimetry of Mice Brain Under Radiofrequency Exposure
Authors: Orlacchio Rosa , Percherancier Yann , Poulletier De Gannes Florence , Hurtier Annabelle , Lagroye Isabelle , Leveque Philippe , Arnaud‐Cormos Delia 
Published: April 2022

This study aims to analyze in real‐time the potential modifications induced by low‐level continuous‐wave and Global System for Mobile Communications radiofrequency (RF) exposure at 1.8 GHz on brain activation in anesthetized mice. A specific in vivo experimental setup consisting of a dipole antenna for the local exposure of the brain was fully characterized. A unique neuroimaging technique based on a functional ultrasound (fUS) probe was used to observe the areas of mice brain activation simultaneously to the RF exposure with unprecedented spatial and temporal resolution (~100 μm, 1 ms) following manual whisker stimulation using a brush. Numerical and experimental dosimetry was carried out to characterize the exposure and to guarantee the validity of the biological results. Our results show that the fUS probe can be efficiently used during in vivo exposure without interference with the dipole. In addition, we conclude that exposure to brain‐averaged specific absorption rate levels of 2 and 6 W/kg does not introduce significant changes in the time course of the evoked fUS response in the left barrel field cortex. The proposed technique represents a valuable instrument for providing new insights into the possible effects induced on brain activation under RF exposure. For the first time, brain activity under mobile phone exposure was evaluated in vivo with fUS imaging, paving the way for more realistic exposure configurations, i.e. awake mice and new signals such as the 5 G networks. © 2022 Bioelectromagnetics Society.