bluuebunny/crossref_metadata_2025_split huggingface dataset:
Foot function in rheumatoid arthritis: Correlation between the Rheumatoid and Arthritis Outcome Score and performance‐based physical tests
Authors: Ben Tekaya Aicha , Ben Dhia Siwar , Hannech Emna , Rouached Leila , Bouden Selma , Tekaya Rawdha , Saidane Olfa , Mahmoud Ines , Abdelmoula Leila 
Published: October 2022

AbstractBackgroundFoot function is usually assessed using self‐reported outcome measures which remain subjective in patients with rheumatoid arthritis (RA). Physical performance tests were recommended for functional assessment in lower limb osteoarthritis. However, foot function assessment's guidelines in RA are lacking. We aimed to investigate the correlation between a self‐reported outcome measure and two performance‐based physical tests for assessing foot function in RA patients.MethodsA cross‐sectional study was performed over 7 months' period including RA patients. We used Rheumatoid and Arthritis Outcome score (RAOS) as a self‐reported functional tool. Physical performance tests were 4‐min walk test (4‐MWT) and Timed up and go test (TUGT).ResultsFifty RA patients were included with 96% females and a mean age of 54.7 ± 10.4 years. Foot involvement occurred since the diagnosis of RA in 36% of patients. Foot pain was reported by 68% of patients (48% forefoot), and foot stiffness in 46% of patients. Skin lesions of the feet were found in 78% of patients, 90% had foot deformities and 56% had inflammatory disorders of feet. Radiographic lesions were found in 94% of patients. The most impaired RAOS subscales were Sports and Recreation and Quality of life.Poor physical‐based performance was found in 34% of RA patients according to 4‐MWT, in 42% of RA patients according TUGT, and in 46% of patients based on at least one performance test. RAOS was negatively correlated to the 4‐MWT and positively correlated in the subscales pain, other symptoms, activities of daily living, and Sport/Rec of the RAOS. Poor performance‐based physical tests were significantly associated with advanced age, sedentary lifestyle, higher disease activity score and impaired functional status. Foot‐related parameters significantly associated with poor performance‐based physical tests were: foot pain, foot deformity and inflammatory disorders. Multivariate analysis identified foot deformities and higher functional impairment as predictive factors for lower gait speed (4‐MWT) and older age and higher functional impairment for higher duration of TUGT.ConclusionRAOS was significantly associated with performance‐based physical function. In the era of connected technologies, these results encourage the regular assessment of rheumatoid foot function by the RAOS score through a connected programme using wearable trackers.
From sacred symbolism to luxury display and consumption: The peacock in medieval Catalonia—Data from zooarcheological, iconographic, and literary evidences
Authors: Fernández Marina , Nadal Maria , Ramos Jordi , Miró Carme , Banks Philip , Nadal Jordi , Riera Santiago , Lloveras Lluís 
Published: October 2022

AbstractThis work presents the first remains of a peacock (Pavo cristatus Linnaeus 1758) discovered in an archeological context in Catalonia. It is a well‐preserved animal (14 remains of an adult female) located in medieval levels—datable to the 13th century (1210–1278 cal. AD) at the site of Carrer de Sotstinent Navarro, in the city of Barcelona. We present the study of the remains of this animal together with that of the other birds recovered from the same excavation. In addition, by referring to iconographic and literary sources, some reflections are made on the species in Catalonia in medieval times. The interpretation of the remains could range from a symbolic religious use of the animal to a more profane one, as an element of identification of social status and economic ostentation, in the field of gastronomy or as an ornamental animal. The study of the remains and their archeological context seem to support this last hypothesis.
Thermosetting epoxidized polybutadiene/low‐molecular weight polyphenylene oxide compatible system with quite low‐dielectric constant and loss prepared through co‐curing reaction
Authors: Dai Tianwen , Jiang Xinyue , Ge Ying , Zou Huawei , Liu Pengbo 
Published: October 2022

AbstractThrough the redistribution reaction of PPO, the hydroxyl‐terminated low molecular weight PPO (PPO‐OH) was prepared. Furthermore, after the reacting of PPO‐OH with methacrylic anhydride, the double‐bond‐terminated low‐molecular weight PPO (R‐PPO) were synthesized, its Mn was 2631 g/mol. The R‐PPO were co‐cured with epoxidized polybutadiene (JP‐100) to prepare JP‐100/R‐PPO cured systems. The JP‐100/R‐PPO cured systems showed single‐phase morphology. The co‐curing reaction with R‐PPO could effectively improve the thermal performance of JP‐100, the glass transition temperature (Tg) of cured JP‐100/R‐PPO systems raised greatly. For the cured JP‐100/R‐PPO (100/30) system, its Tg was 192°C. The dielectric constant and dissipation factor of cured JP‐100/R‐PPO systems were both decreased and showed good frequency stability. The dielectric constant and dissipation factor at 1 MHz of cured JP‐100/R‐PPO (100/30) system were 2.61 and 0.0038, respectively, were obviously lower than those of cured JP‐100 system (which were 3.10 and 0.0099, respectively). The JP‐100/R‐PPO systems exhibited an excellent thermal stability. The 5% weight loss temperature (T5%) of cured JP‐100/R‐PPO system was around 340°C.
A review of salt occurrences in soils of the Transantarctic Mountains, Antarctica
Authors: Campbell Iain B. , Sheppard Douglas S. 
Published: October 2022

AbstractSalts are pervasive throughout the Transantarctic Mountains cold desert soils and are derived primarily from atmospheric sources. Their composition is varied and dependent on local or regional climatic conditions. Their presence within soil profiles ranges from small flecks to continuous salt horizons and their abundance and distribution have a distinct relationship with climatic attributes and land surface age which extends back to the Miocene. While liquid water is seldom present, salts are present in saturated solutions surrounding mineral grains in the soil and may move deeply into the soil or underlying icy permafrost. Extensive ground surface salt efflorescence occurs on freshly exposed surfaces that have been disturbed by human activities, the salts being derived from within the thawed permafrost ice.
Simulating the Effects of Grain Surface Morphology on Hot Spots in HMX with Surrogate Model Development
Authors: Springer H. Keo , Miller Christopher M. , Kroonblawd Matthew P. , Bastea Sorin 
Published: October 2022

AbstractThere have been several numerical studies on the collapse of internal voids in energetic grains but fewer investigations have probed grain‐grain interface effects. In this study, we examine the effects of grain surface morphology and binder conditions on hot spot mechanisms during shock loading using the multi‐physics hydrocode, ALE3D, coupled with the thermochemical code, Cheetah. To improve the accuracy of our grain‐scale simulations, the HMX material models have been updated from previous studies to incorporate new property predictions from molecular dynamics simulations. In our simulations of the interface between two neighboring energetic grains, the upstream grain surface is described by a single sinusoid with amplitude (0.5–2 μm) and wavelength (0.5–2 μm). The effects of grain surface coating, i. e., no binder, partially coated, and fully coated with binder, is also explored. A range of shock loading pressures (10–30 GPa) is considered. Binder coating reduces hot spots at grain‐grain interfaces by limiting plastic deformation and heating of upstream grain surfaces as well as preventing transmission of localized deformation modes (e. g., jetting) to the downstream grain. More plastic work and heating is observed with new HMX material models versus the previous models because the strength does not thermally soften as much as a result of the higher melt temperature; this also reduces vortical flow and jetting mechanisms with the new HMX material models. A surrogate model based on neural networks is developed for the early stage reaction rate. Physics‐based input features improve the performance of the neural networks over basic input features alone with a root mean squared error=1.05 μs−1 and R2=0.98. Accurate and fast‐running surrogate models can effectively serve as structure‐property‐sensitivity relationships.
High‐Pressure Characterization of Two Stereoisomers of Tetranitroester Cyclobutane
Authors: Bennion Jonathan C. , Jenkins Timothy A. 
Published: October 2022

AbstractThe high‐pressure behavior of two stereoisomeric cyclobutane nitric ester materials were studied at room temperature to near 25 GPa via Raman spectroscopy and powder X‐ray diffraction. The materials investigated included [cis‐trans‐cis]‐ and [all‐cis]‐tetranitrate ester cyclobutanes. Over the course of these studies no evidence of polymorphism was observed, highlighting the stability of the ambient pressure crystal structures of the cyclobutanes to conditions near the detonation pressure of the material. Differences were observed between the bulk moduli of the two stereoisomers, suggesting potential tunability in materials response under dynamic conditions through the use of isomeric materials. Such findings suggest that these high‐performance materials can serve as TNT replacement in novel melt‐castable energetic formulations without the concern of uncontrolled polymorphism that might otherwise affect the performance and safety of a munition.
Piper longum L.: A comprehensive review on traditional uses, phytochemistry, pharmacology, and health‐promoting activities
Authors: Biswas Protha , Ghorai Mimosa , Mishra Tulika , Gopalakrishnan Abilash Valsala , Roy Debleena , Mane Abhijit Bhagwan , Mundhra Avinash , Das Neela , Mohture Vikas Moreshwar , Patil Manoj Tukaram , Rahman Md. Habibur , Jha Niraj Kumar , Batiha Gaber El‐Saber , Saha Suchismita Chatterjee , Shekhawat Mahipal S , Radha  , Kumar Manoj , Pandey Devendra Kumar , Dey Abhijit 
Published: October 2022

AbstractPiper longum (family Piperaceae), commonly known as “long‐pepper” or “Pippali” grows as a perennial shrub or as an herbaceous vine. It is native to the Indo‐Malaya region and widely distributed in the tropical and subtropical world including the Indian subcontinent, Sri Lanka, Middle‐East, and America. The fruits are mostly used as culinary spice and preservatives and are also a potent remedy in various traditional medicinal systems against bronchitis, cough, cold, snakebite, and scorpion‐sting and are also used as a contraceptive. Various bioactive‐phytochemicals including alkaloids, flavonoids, esters, and steroids were identified from the plant extracts and essential oils from the roots and fruits were reported as antimicrobial, antiparasitic, anthelminthic, mosquito‐larvicidal, antiinflammatory, analgesic, antioxidant, anticancer, neuro‐pharmacological, antihyperglycaemic, hepato‐protective, antihyperlipidaemic, antiangiogenic, immunomodulatory, antiarthritic, antiulcer, antiasthmatic, cardioprotective, and anti‐snake‐venom agents. Many of its pharmacological properties were attributed to its antioxidative and antiinflammatory effects and its ability to modulate a number of signalling pathways and enzymes. This review comprehensively encompasses information on habit, distribution, ethnobotany, phytochemistry, and pharmacology of P. longum in relation to its medicinal importance and health benefits to validate the traditional claims supported by specific scientific experiments. In addition, it also discusses the safety and toxicity studies, application of green synthesis and nanotechnology as well as clinical trials performed with the plant also elucidating research gaps and future perspectives of its multifaceted uses.
Generation and Structuring of Multipartite Entanglement in a Josephson Parametric System
Authors: Petrovnin Kirill Viktorovich , Perelshtein Michael Romanovich , Korkalainen Tero , Vesterinen Visa , Lilja Ilari , Paraoanu Gheorghe Sorin , Hakonen Pertti Juhani 
Published: October 2022

AbstractQuantum correlations are a vital resource in advanced information processing based on quantum phenomena. Remarkably, the vacuum state of a quantum field may act as a key element for the generation of multipartite quantum entanglement. In this work, generation of genuine tripartite entangled state and its control is achieved by the use of the phase difference between two continuous pump tones. Control of the subspaces of the covariance matrix for tripartite bisqueezed state is demonstrated. Furthermore, by optimizing the phase relationships in a three‐tone pumping scheme genuine quadripartite entanglement of a generalized H‐graph state (‐graph) is explored. This scheme provides a comprehensive control toolbox for the entanglement structure and allows to demonstrate, for first time to the authors' knowledge, genuine quadripartite entanglement of microwave modes. All experimental results are verified with numerical simulations of the nonlinear quantum Langevin equation. It is envisioned that quantum resources facilitated by multi‐pump configurations offer enhanced prospects for quantum data processing using parametric microwave cavities.
Automating sandhill crane counts from nocturnal thermal aerial imagery using deep learning
Authors: Luz‐Ricca Emilio , Landolt Kyle , Pickens Bradley A. , Koneff Mark 
Published: October 2022

AbstractPopulation monitoring is essential to management and conservation efforts for migratory birds, but traditional low‐altitude aerial surveys with human observers are plagued by individual observer bias and risk to flight crews. Aerial surveys that use remote sensing can reduce bias and risk, but manual counting of wildlife in imagery is laborious and may be cost‐prohibitive. Therefore, automated methods for counting are critical to cost‐efficient application of remote sensing for wildlife surveys covering large areas. We conducted nocturnal surveys of sandhill cranes (Antigone canadensis) during spring migration in the Central Platte River Valley of Nebraska, USA, using midwave thermal infrared sensors. We developed a framework for automated counting of sandhill cranes from thermal imagery using deep learning, assessed and compared the performance of two automated counting models, and quantified the effect of spatial resolution on counting accuracy. Aerial thermal imagery data were collected in March 2018 and 2021; 40 images were analyzed. We applied two deep learning models: an object detection approach, Faster R‐CNN and a recently developed pixel‐density estimation approach, ASPDNet. Model performance was determined using data independent of the training imagery. The effect of spatial resolution was quantified with a beta regression on relative error. Our results showed model accuracy of 9% mean percent error for ASPDNet and 18% for Faster R‐CNN. Most error was related to the undercounting of sandhill cranes. ASPDNet had <50% of the error of Faster R‐CNN as measured by mean percent error, root‐mean‐squared error and mean absolute error. Spatial resolution affected accuracy of both models, with error rate increasing with coarser resolution, particularly with Faster R‐CNN. Deep learning models, particularly pixel‐density estimators, can accurately automate counting of migratory birds in a dense, aggregate setting such as nocturnal roosting sites.
Conductive Iodine‐Doped Red Phosphorus Enabled Dendrite‐Free Lithium Deposition on MXene Matrix
Authors: Na Zhaolin , Li Wenjing , Li Lin , Qi Houkai , Sun Jing , Lu Chunlan , Sun Xudong , Huang Gang 
Published: October 2022

AbstractThe highest theoretical capacity and lowest redox potential of lithium metal make lithium‐based batteries the “holy grail” of the next‐generation batteries. However, the uncontrollable dendrite growth and infinite volume change of lithium seriously hinder the real‐world implementation of lithium‐based batteries. Herein, a flexible MXene@iodine‐doped red phosphorus (MXene@RP) paper with iodine‐doped red phosphorous particles evenly distributed on the surface and interlayer of MXene matrix is designed by a simple vapor condensation reduction approach. The MXene@RP paper can be used as an efficient matrix to enable dendrite‐free lithium deposition. On the one hand, the iodine doping alleviates the low conductivity shortcoming of red phosphorus, making it facilitate homogeneous lithium nucleation, thus promoting uniform lithium deposition and suppressing dendrite growth. On the other hand, the unique layered structure of conductive MXene paper provides ion transport channels and free spaces for lithium loading, alleviating the volume change induced structural damage. As a result, the MXene@RP paper with preloaded lithium exhibits long‐term cycling stability. Particularly, a full cell based on Li‐MXene@RP anode can maintain 81.4% of the initial capacity after 600 cycles at 4 C. The MXene@RP‐based anode increases the potential applications of MXene and provides a guide for the design of dendrite‐free lithium hosts.
What are the benefits and opportunities of launching a Metaverse forNEOMcity?
Authors: Banaeian Far Saeed , Imani Rad Azadeh 
Published: October 2022

AbstractIt is expected that in , the first phase of the most innovative city in the world will be opened. Seemingly NEOM city's developers have forgotten about an attractive technology called Metaverse, presented almost simultaneously along with the NEOM idea in . This study stipulates that Metaverse can appreciably assist in delivering a broad digital perspective of the future to governments, futurologists, people, and particularly the NEOM developers. Also, this study briefly addresses the benefits and opportunities of releasing Metaverse‐based NEOM for the Kingdom of Saudi Arabia (KSA), engineers, developers, futurologists, and people worldwide. Moreover, it is illustrated that KSA and people worldwide can benefit from the Metaverse version. For example, people can visit the world's dream city as digital tourists. As a result of this revolutionary idea, KSA can earn considerable revenue by land pre‐selling and providing remote services.
Prior hospital‐based infection and risk of eosinophilic esophagitis in a Swedish nationwide case‐control study
Authors: Uchida Amiko M. , Ro Gabrielle , Garber John J. , Roelstraete Bjorn , Ludvigsson Jonas F. 
Published: October 2022

AbstractBackground and AimsEosinophilic esophagitis (EoE) is an increasingly common, largely food allergen‐driven disease characterized by dysphagia. Prior infections are known to associate with other loss of tolerance diseases such as autoimmunity. We aimed to determine if antecedent infection was associated with later EoE development.MethodsWe performed a case‐control study of all patients with biopsy‐verified EoE diagnosed between 2000 and 2017 in Sweden (n = 1587) and matched to 5 general population controls (n = 7660). Cases were identified using histopathology codes from the Epidemiology Strengthened by histopathology Reports in Sweden study, a validated cohort of gastrointestinal pathology reports from all 28 pathology centers in Sweden. We used logistic regression to estimate odds ratios (ORs) and 95% confidence intervals for antecedent infections from patients seen at hospital‐based outpatient clinics or inpatients. In secondary analyses, we compared EoE patients with their full siblings to further reduce residual confounding.Results564 (35.7%) EoE patients and 1793 (23.4%) matched controls had an earlier record of infection. This corresponded to a 2‐fold increased risk of infections in EoE patients (OR 2.01; 95%CI: 1.78–2.27). ORs for earlier gastrointestinal or respiratory infection were 2.73 (n = 128 EoE, 268 control; 95%CI: 2.17–3.41) and 1.89 (n = 305 EoE, 960 control; 95%CI: 1.63–2.20), respectively. Having an EoE diagnosis was linked to a 3.39‐fold increased odds of sepsis (n = 14 EoE, 21 control; 95%CI: 1.68–6.65). Individuals with EoE were also more likely to have had an infection compared to their non‐EoE siblings (n = 427 EoE, 593 control; OR = 1.57; 95%CI = 1.30–1.89).ConclusionIn this nationwide cohort study, prior infection, was associated with subsequent EoE. Risks were particularly high after sepsis, and gastrointestinal or respiratory infections.
Induction of apoptosis by essential oil of Dracocephalum kotschyi on Trichomonas vaginalis
Authors: Chelgerdi Dehkordi Bahareh , Esmaeilifallah Mahsa , Kalantari Reza , Benchimol Marlene , Khamesipour Faham 
Published: October 2022

AbstractBackgroundTrichomonas vaginalis is a protist parasite that causes trichomoniasis, a sexually transmitted disease. Metronidazole is the current treatment for trichomoniasis. However, this drug can provoke severe side effects, and some strains present resistance, making the development of alternative treatments for trichomoniasis urgent.ObjectivesWe investigate the use of essential oil obtained from Dracocephalum kotschyi on T. vaginalis. D. kotschyi has antispasmodic and analgesic properties and is well known in Iran.MethodsThe essential oil was obtained by hydrodistillation from 1000 g of the powdered plant. Gas chromatography‐mass spectrometry analysis was used for the chemical composition of the essential oil, and 11 substances were identified, corresponding to 91.5% of the oil. Copaene (22.15%), Methyl geranate (16.31%), Geranial (13.78%) and Carvone (11.34%) were the main substances. A cell viability test was used to determine the percentage of growth inhibition (GI%) and the half‐maximal inhibitory concentration (IC50) on T. vaginalis after incubation with the prepared essential oil.ResultsThe oil induced an IC50 of 84.07 µg/ml after 24 h contact with trophozoites. Cytotoxicity was determined by MTT assay on the J774.A1 haematopoietic cell line. In addition, the initial stage of apoptosis was assayed using the fluorescein isothiocyanate Annexin V Apoptosis Detection Kit. Evaluation of the in vitro anti‐trichomonal properties of D. kotschyi essential oils showed that it effectively induces apoptosis on T. vaginalis between 100 and 700 µg/ml after 48 h without toxicity on haematopoietic cells, suggesting that D. kotschyi essential oil can induce programmed death in T. vaginalis.ConclusionsThe anti‐trichomonal properties of D. kotschyi essential oil indicate that they could be suitable for new pharmacologic studies after new tests with human vaginal epithelial cells.
Recent developments in multivariate wind and solar power forecasting
Authors: Sørensen Mikkel L. , Nystrup Peter , Bjerregård Mathias B. , Møller Jan K. , Bacher Peder , Madsen Henrik 
Published: October 2022

AbstractThe intermittency of renewable energy sources, such as wind and solar, means that they require reliable and accurate forecasts to integrate properly into energy systems. This review introduces and examines a selection of state‐of‐the‐art methods that are applied for multivariate forecasting of wind and solar power production. Methods such as conditional parametric and combined forecasting already see wide use in practice, both commercially and scientifically. In the context of multivariate forecasting, it is vital to model the dependence between forecasts correctly. In recent years, reconciliation of forecasts to ensure coherency across spatial and temporal aggregation levels has shown great promise in increasing the accuracy of renewable energy forecasts. We introduce the methodology used for forecast reconciliation and review some recent applications for wind and solar power forecasting. Many forecasters are beginning to see the benefit of the greater information provided by probabilistic forecasts. We highlight stochastic differential equations as a method for probabilistic forecasting, which can also model the dependence structure. Lastly, we discuss forecast evaluation and how choosing a proper approach to evaluation is vital to avoid misrepresenting forecasts.This article is categorized under:
Climate and Environment > Net Zero Planning and Decarbonization
Sustainable Energy > Solar Energy
Sustainable Energy > Wind Energy