bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associação entre alodinia cutânea e frequência, intensidade e duração da migrânea na população pediátrica – estudo piloto
Authors: Santos Michelle Aparecida Anjos , Pradela Juliana , Dach Fabíola , Bevilacqua-Grossi Débora 
Published: February 2022

Introdução
A migrânea afeta 9,1% de crianças e adolescentes e pode ocasionar crises de curta duração, intensidade variável, podendo ser crônica ou episódica. Embora o processo de sensibilização central seja conhecido na migrânea, ainda não está estabelecida a relação entre a alodinia cutânea e as características da crise em crianças e adolescentes.
Objetivo
Avaliar a associação da alodinia cutânea com as características da migrânea na população pediátrica.
Métodos
Este é um estudo piloto, com desenho transversal, que avaliou 17 pacientes com migrânea (12,1 anos, DP 3,2) de ambos os sexos, recrutados no Ambulatório de Cefaleia Infantil do Hospital das Clínicas de Ribeirão Preto. Os pacientes preencheram um questionário estruturado sobre a frequência, intensidade e duração da migrânea, e em seguida responderam ao Questionário de Alodinia baseado no ICHD-III versão beta (adaptado), composto por 4 questões que avaliam a presença ou ausência da alodinia cutânea durante crises de migrânea. Pacientes que apresentaram pelo menos duas respostas positivas foram classificados com alodinia cutânea. O estudo foi aprovado pelo Comitê de Ética em Pesquisa (CAAE 31864020.0.0000.5440). A correlação de Spearman (p<0,05) foi aplicada para avaliar a associação entre as variáveis.
Resultados
A alodinia cutânea foi observada em 53% dos pacientes. Todos os participantes apresentaram migrânea episódica (frequência 3,0 dias por mês; DP 2,3), intensidade de dor leve (2,2; DP 0,7) e curta duração (5,4 horas; DP 5,2). Não foram observadas correlações significativas entre a presença de alodinia e a frequência (rho=0,01; p=0,96), intensidade (rho=0,37; p=0,13) e duração (rho= -0,02; p=0,92) das crises de migrânea.
Conclusão
Os dados deste estudo piloto sugerem que a alodinia cutânea não está associada com a apresentação clínica da crise migranosa em crianças e adolescentes.
Monitorização não invasiva da pressão intracraniana em pacientes com queixa de cefaleia: série de casos
Authors: Cherain Luiz Gabriel Gonçalves , Barbosa Mateus Gonçalves de Sena , Francisco Ghaspar Gomes de Oliveira Alves , Frigieri Gustavo , Rabelo Nícollas Nunes 
Published: February 2022

Introdução
O aumento da pressão intracraniana (PIC) constitui um conjunto de sinais e sintomas relacionados à alteração do volume e da pressão intracraniana, essas alterações são visíveis em diversas doenças neurológicas, o que inclui a cefaleia. Em pacientes com cefaleia crônica a monitorização da pressão intracraniana é realizada de maneira não invasiva o que traz menores danos ao paciente e rapidez nos resultados. O objetivo deste trabalho é elucidar como a monitorização não invasiva da pressão intracraniana em pacientes com cefaleia é realizada e as conclusões a partir da monitorização.
Metodologia
Estudo de série de casos retrospectiva, onde foram coletados dados clínicos de 32 pacientes atendidos em consultório entre dezembro de 2020 a setembro de 2021, com cefaleia (exceto do tipo enxaqueca), sem restrição de sexo, idade, cor, raça e nível socioeconômico. Todos foram submetidos a monitorização não invasiva da pressão intracraniana por um dispositivo da Brain4care.
Resultados
Dos 32 pacientes analisados, foi observado que a relação P2/P1 teve seu valor aumentado, com uma média de valores de 1,15 (0,82-1,62). O time to peak teve uma média de 0,23 (0,04-0,34). Esses dados tendem a indicar um aumento da pressão intracraniana e uma diminuição na complacência cerebral em pacientes que relataram queixa de cefaleia. A monitorização não invasiva é importante pois possibilita as medições no consultório, fora do ambiente hospitalar.
Conclusão
O dispositivo de monitorização não invasiva mostrou uma relação entre o aumento da PIC e a queixa de cefaleia. A vantagem é que a medição pode ser realizada no consultório, utilizando a tecnologia a favor da segurança e conforto do paciente.
Influência das variantes genéticas +874T>A e -764G>C do Interferon-γ na suscetibilidade à migrânea
Authors: Bossa Beatriz Bagatim , Salomão Giovana Rodrigues , Lima Giovanna Sguissardi , Rocha Amanda Brant , Bello Valéria Aparecida , Frederico Regina Célia Poli , Silva Aline Vitali 
Published: February 2022

IntroduçãoA migrânea é um distúrbio neurológico incapacitante e geneticamente determinado. Níveis elevados do interferon-γ(IFN-γ), citocina pró-inflamatória, contribuem para desencadear a dor.
ObjetivoAvaliar o efeito das variantes genéticas +874 T>A e -764 G>C do IFN-γ e seu efeito sobre a suscetibilidade e sintomasassociados à migrânea.
Material e métodosEstudo prospectivo do tipo caso-controle composto por 144 participantes entre 18 e 60 anos diagnosticados commigrânea e controles saudáveis. Projeto aprovado pelo Comitê de Ética em Pesquisa da PUCPR (n°3.029.972). Osparticipantes foram avaliados e responderam a entrevista estruturada sobre dados demográficos, antropométricos,clínicos, classificação e sintomas associados à migrânea. Também preencheram questionários validados referentesà incapacidade relacionada à migrânea (MIDAS), ansiedade (STAIY2) e depressão (IDB). A variantes genéticasdo IFN-γ foram analisadas por meio da reação em cadeia da polimerase com primers sequência alelo específica(PCR-SSP) ou PCR em tempo real. Foi realizada análise univariada seguida de regressão logística binária. Foi consideradadiferença estatística quando p<0,05.
ResultadosForam avaliados 144 indivíduos, sendo 68 com migrânea e 76 controles pareados para sexo, idade, etnia e índicede massa corporal. Pacientes com genótipo GC, da variante -764, apresentaram menor chance de migrânea quandocomparados com o genótipo GG (OR=0,15; p=0,047), maior produtor da citocina. Esse resultado corroboracom estudos clínicos que demonstraram aumento do IFN-γ em indivíduos com migrânea, especialmente na fase dedor5,6. Entretanto, a variante +874T>A não se associou à suscetibilidade à migrânea. Também não houve diferençaestatística entre os diferentes genótipos de ambas as variantes analisadas quanto ao tipo, presença ou ausência deaura, fotofobia, fonofobia, osmofobia, alodinia, depressão ou incapacidade da migrânea.
ConclusãoIndivíduos heterozigotos (GC) para variante -764 G/A do IFN-γ apresentaram chance 85% menor de apresentaremmigrânea quando comparados aos homozigotos GG.
Author’s Reflections on <em>Making Sense of Numbers: Quantitative Reasoning for Social Research</em>
Authors: Miller Jane 
Published: February 2022

Miller, Jane E. 2021. Making Sense of Numbers: Quantitative Reasoning for Social Research. (Los Angeles: SAGE Publications) 608 pp. ISBN 978-1544355597.
This article introduces and provides an excerpt from Making Sense of Numbers: Quantitative Reasoning for Social Research, published by Sage. The book explains and illustrates how making sense of numbers involves integrating concepts and skills from mathematics, statistics, study design, and communications, along with information about the specific topic and context under study. It teaches how to avoid making common errors of logic, calculation, and interpretation by introducing a systematic approach and a healthy dose of skepticism to understanding and applying numbers to social research and everyday tasks.
Secondary traumatic stress among police officers –
the relationship with personality and ruminations
Authors: Ogińska-Bulik Nina , Bąk Grzegorz , Michalska Paulina 
Published: February 2022

IntroductionLike many professionals who work with victims of trauma, police officers may experience negative consequences expressed in the form of secondary traumatic stress (STS) symptoms. The study aim was to establish the relationship between personality, ruminations (intrusive and deliberate) and secondary traumatic stress symptoms, including the mediating role of ruminations, in a group of police officers exposed to secondary trauma.Material and methodsA group of 235 police officers working, at least partly, with trauma victims were surveyed. The age of the participants ranged from 30 to 60 years (M = 40.79, SD = 3.96). Three questionnaires were used: the Secondary Traumatic Stress Inventory, the NEO Five-Factor Inventory and the Event-Related Rumination Inventory.ResultsThe results demonstrate a rather low level of STS among police officers. Ruminations, particularly intrusive ones, were more strongly connected with symptoms of STS than personality traits. Neuroticism correlated more strongly with STS than other personality traits, and extraversion was not connected with any negative effects of secondary trauma exposure. The conducted analysis confirmed that ruminations act as mediators in the relationship between neuroticism and STS.ConclusionsAlthough the police officers working with trauma victims revealed low levels of STS symptoms, it is nevertheless advisable to ameliorate, if not prevent, them. Interventions should aim to expand the competencies in coping with trauma, including reducing the tendency to ruminate about the traumatic events experienced by clients.
Clinical characteristics and health outcomes in patients with alcohol withdrawal syndrome: an observational study from Oman
Authors: Al-Maqbali Juhaina Salim , Al-Maqrashi Nasiba , Al-Huraizi Aisha , Al-Mamari Qasim Sultan , Al Alawa Khalifa , Al Alawi Abdullah M. 
Published: February 2022

BACKGROUND:
Globally, alcohol withdrawal syndrome (AWS) is considered a serious medical diagnosis associated with increasing morbidity and mortality. Little information has been reported on the scope of the problem in Oman.

OBJECTIVE:
Study clinical characteristics, management, quality of care, and health outcomes of patients managed for AWS.

DESIGN:
Retrospective medical record review.

SETTINGS:
University hospital.

PATIENTS AND METHODS:
The study included all patients with AWS admitted from 1 October 2019 to 30 September 2020. We collected demographic and clinical characteristics and did a univariate analysis of factors related to 90-day readmission.

MAIN OUTCOME MEASURES:
Length of hospital stay, 90-day read-mission, referral rate to alcohol rehabilitation center.

SAMPLE SIZE AND CHARACTERISTICS:
150 male patients with median (IQR) age of 39.5 (32-48) years.

RESULTS:
Most patients (70.7%, n=106) were smokers and 44 (29.3%) had a history of drug abuse. The average length of hospital stay was 2.3 (0.9-4.6) days. Approximately 9% of total hospital bed days were used to care for patients with AWS. Chronic liver disease (35.3%), diabetes mellitus (24.7%), and hypertension (24.0%) were common among AWS patients. The 90-day readmission rate (32.7%) was high, and there was low referral to alcohol rehabilitation (16.7%). Diabetes and epilepsy were associated with 90-day readmission.

CONCLUSION:
AWS is an important diagnosis that represents an important burden on acute medical services. Establishing a drug and alcohol service in our institution is an essential step to optimise care for patients with alcohol-related disorders.

LIMITATIONS:
Retrospective, so unable to collect data on manifestations of AWS such as delirium tremens, which is the most severe form of AWS. Also, the reason for the lack of referral to an outpatient alcohol rehabilitation program was not apparent.

CONFLICT OF INTEREST:
None.
Translating the Chthulucene: Rasa Smite and Raitis Smits’ Atmospheric Forest as Post-Anthropocentric Visuality
Authors: Buchmueller Sophie 
Published: February 2022

Depicting the Anthropocene is a fraught endeavor, as visual documentation often falls back on an illustrative mode that attempts to encapsulate the immensity of climate change in a single snapshot. Similarly, even the term Anthropocene is contested territory, as it is arguably too myopic to account for the full range of activities occurring in our present moment of ecological crisis. Pointing to the need to decenter humans and engage with the emergent, multilayered entanglements that compose our world, Donna Haraway proposes the “Chthulucene” as a more fitting conceptualization of our current epoch. In this paper, I argue that visual culture originating from a Chthulucenic perspective provides an opportunity to transcend the crushing anthropocentrism plaguing conventional documentation of climate change, and offers compelling models for multispecies aesthetic experiences and communications.
My discussion focuses on Latvian artists Rasa Smite and Raitis Smits’ Atmospheric Forest (2020), a virtual reality installation that exposes the interplay between a Swiss alpine forest, the atmosphere, and global warming. Trees breathe, taking in carbon dioxide and exhaling oxygen along with large amounts of volatiles and resin, an exchange imperceptible to the naked eye. Atmospheric Forest visualizes and sonifies this process, immersing the viewer in a point-cloud data scan of the forest. I argue that the piece functions as what Sean Cubitt calls “geomedia,” or data collection and visualization methods that crucially translate non-human phenomena into humanly observable forms. By making visible intricate ecological relations between living and nonliving actors, Atmospheric Forest successfully resists the limitations of Anthropocene visuality and operates within a Chthulucenic worldview. In doing so, the work serves as an access point into some of the interlaced connections of Gaia, as theorized by James Lovelock and Lynn Margulis, and ultimately encourages viewers to pay closer attention to these complex ecologies and care for their biodiverse companions.
Editorial
Authors: García Murcia Joaquín 
Published: February 2022

En el plano de la actividad legislativa, el segundo semestre de 2020 ha presentado rasgos muy similares al primero, principalmente por la continuidad del estado de alarma, que para esos meses fue declarado a través de sucesivas normas gubernamentales y, en su tramo final, por el RD 926/2020, de 25 de octubre, prorrogado por el RD 956/2020, de 3 de noviembre. También se ha caracterizado, como los primeros trimestres del año, por la aprobación continuada de normas legales de urgencia de contenido diverso (social, económico e institucional, fundamentalmente), para paliar los múltiples y variados efectos de la pandemia Covid-19. Con un ritmo de aparición similar al de sus precedentes más inmediatos, el paquete de disposiciones legales de raíz gubernamental puesto en marcha en esta segunda franja temporal de 2020 ha discurrido desde el RDL 25/2020, de 3 de julio, de reactivación de la actividad económica y el empleo, hasta el RDL 39/2020, de 29 de diciembre, de medidas de apoyo social y económico, con otras muchas normas intermedias de equivalente tonalidad.
Глиняний посуд у поховально-поминальній обрядовості лісостепового населення
скіфського часу Дніпровського Лівобережжя
Authors: Гейко Анатолій 
Published: February 2022

Розглянуто використання глиняного посуду в поховальних та поминальних обрядах
населенняскіфського часу Дніпровського Лісостепового Лівобережжя. Простежено, що вироби
місцевого таімпортного походження були досить частою знахідкою в насипах курганів, а
також у ровах, що їхоточували. Ці глиняні артефакти пов’язані з очисними ритуалами,
напутніми дарами й тризною. The use of clay pottery in the Scythian population’s
burial and memorial rituals of the Dnipro Left-Bank Forest-Steppe Region is considered
in the article. It has been traced that the locally made productsand imported antiques
were quite frequent finds in the mounds, as well as in the ditches that surroundedthem.
These clay artifacts are associated with purification rituals, farewell gifts, and
funeral meal.Despite the similarities (ethnic, religious, cultural, territorial)
monuments of the Dnieper Forest-Steppe Left Bank Region, complete unity in burial
customs in the 8th-4th centuries BC didn’t observe.It shows the heterogeneity of the
population’s burial rituals, even in some close regions, and possiblechronological
changes in the whole ritual.We can observe quite similar rituals during the diggings of
simultaneous burials in the DnieperForest-Steppe Right Bank Region and Ukraine steppe
zone’s Scythian mounds.Unfortunately, most of the mounds were looted in ancient times.
It is not yet possible to trace clearlythe differences in burial rituals for
socio-property differentiation of the dead.Examining clay pottery, it can be confirmed
that the local population’s burial rituals with using theseartifacts were not
conservative. Imported antique products had been using actively in them from the
5thcentury BC.The same clay pottery was used in everyday life and burial rituals.
Analysis of clay pottery’s contentsusing DNA technology will determine what food was in
them.New archаeological diggings of mounds and soil necropolises, expansion of source
base will allowtracking changes in burial rituals in space and time.
Ефект мультиплікації в декоруванні посуду доби пізньої бронзи
Authors: Отрощенко Віталій 
Published: February 2022

Проаналізовано систему декорування доби пізньої бронзи. Розглянуто ефект
мультиплікаціїв оздобленні глиняного посуду означеного періоду. The era of light
chariots with wheels on spokes drawn by horses was the prologue to the
epoch-makingchanges in the transition to the Late Bronze Age. It can be assumed that the
contemplation of the rapidmovement of wheels on spokes gave almost the first idea of the
effect of multiplication in the societies ofSteppe cattlemen. The vortex effect of the
rotational movement of the wheel led to the image of the swastika,i.e. the sacred symbol
of the Aryan chariots. The rotation of the swastika mounted on the axle creates
anoptical effect of the wheel on the spokes. It was recorded in cases when the swastika
was inscribed fromthe outside in the circle of the bottom of the pot. The effect was
enhanced when the vessel (cup) had abase, and the circle of the base together with the
swastika was even more harmoniously associated withthe rim of the wheel. Rotating the
cup in an upside down position on a mobile stand allows you to achievethe effect of
animation in the context of the ritual. The era of unprecedented speeds gave impetus to
thecreation of new dynamic spectacles. Among them were acrobatic games with a bull,
artistically embodiedin the frescoes of the Minos Palace on the island of Crete and
other examples of Cretan and MycenaeanArt. Episodes of this game have been recorded in
the ancestral homeland of the Mycenaean rulers inthe steppes of Eurasia and in the South
Caucasus, in particular petroglyphs of Gobustan, pictograms onceramics and metal. The
study is based on a number of assumptions. The author does not have access tothese
artefacts, which are currently contained in the museum collections of the four states.
But with theirsize, shape and illustrations of iconic compositions, you can make copies,
put on a potter's wheel and tryto rotate at different speeds to see if the effect of
animation will play on these objects.
Дослідження ліпленої кераміки з Басівського городища
Authors: Корж Антон 
Published: February 2022

Висвітлено історію досліджень центральної поселенської пам’ятки Посулля скіфського
часу –Басівського городища. Проаналізовано ступінь вивченості та опрацювання гончарного
комплексу.Розглянуто результати новітніх досліджень і перспективність застосування
природничихметодів, зокрема рентген-флуоресцентного, для аналізу елементного складу
ліпленої кераміки. The history of the studies of the second largest Scythian
settlement of the Dnieper Left-Bankforest-steppe – Basivka hill-fort, which is directly
the key monument in the Sula river basin microregion,is revealed in the article. The
peculiarities of studying such a category of material culture as handmadeceramics are
highlighted. It has been established that certain works on ceramics, which would relate
purelyto materials from the Basivka hill-fort, have not been published to date, which
complicates further work.During the prospecting of the nearest area of the monument by
the Basivka detachment of the PutyvlArchaeological Expedition in 2020, new, promising
for further research, settelements and locationswere discovered. For the first time, the
method of natural sciences was used to study ceramics from themonuments of the Scythian
period. The author publishes the results of analyzes of ceramics from theBasivka
hill-fort made by non-destructive X-ray fluorescence method. The conclusions show the
prospectsfor further cooperation of archaeologists and physicists in the study of
handmade pottery of the Scythiantime, not only in this micro-region, but also in general
in Ukraine.
Особливості реставрації великогабаритних ліплених посудин (досвід використання
3D-моделювання в реставрації)
Authors: Волков Анатолій , Петрашина Поліна 
Published: February 2022

Подано інформацію про застосування методів фотограмметрії, зокрема 3D-моделювання,
підчас реставрації ліпленого глиняного посуду. Поетапно розглянуто процес створення
тривимірноїмоделі та її практичне використання під час реставраційних робіт.
Сonservation of archaeological handmade ware, especially of the large size, has certain
featuresand difficulties due to firing at low temperatures and the composition of the
molding mass (the clay wascoarse with large inclusions).Such vessels usually come to our
time in a worse condition than pottery, mostly in a form ofa collapses broken into many
fragments, with a fragile surface, so they require a special approach to thechoice of
methods, techniques and materials used for their restoration. In such cases the main
task forthe conservator is to find such methods of working with handmade vessels, which
on the one hand wouldbe completely safe, on the other – would provide the comprehensive
study, restoration and preservationof broken archaeological ceramics.It should be noted
that with the development of digital technologies in archaeology and restoration,the
methods of photogrammetry used in non-invasive research of archaeological sites have
spread.The article deals with the application of photogrammetry methods, in particular
3-d modeling duringrestoration work with handmade ware of a large sizes. We try to
describe in detail the way of creatinga three-dimensional model at the stage of
photo-fixation of the archaeological vessel before the beginningof restoration measures
using as the example the handmade large pot (korchaga) of Sabatyn culture ofthe Late
Bronze Age.In our case, a three-dimensional model of the exhibit was created to simplify
the selection of fragmentsfor gluing (almost similar in shape and size) before the
dismantling of a partially glued exhibit of 147fragments. Prior to photography, all
fragments of the vessel were marked with paper stickers.Agisoft Photoscan v1.4.4
software was used for 3D reconstruction of the object.
A clinical case of acute myeloid leukemia
mimicking a tumor
of the Ewing sarcoma family
Authors: Baiturova S. M. , Omarova K. O. , Boranbaeva R. Z. , Abdilova G. K. , Pankova O. S. , Bekisheva A. N. , Makhneva A. F. , Batyrkhanova G. Z. , Kustova T. A. 
Published: February 2022

Relevance: M6 variant of acute myeloid leukemia is extremely rare
in pediatric practice. The diverse clinical manifestations of erythroblastic leukemia complicate the timely diagnosis of this group of diseases.
Purpose: to describe a clinical case of congenital erythroblastic
leukemia with multiple lesions of soft tissues and the skeletal system
with complications in the form of the convulsive syndrome, presented
as an Ewing’s sarcoma tumor, diagnosed at the Research Center of
Pediatrics and Pediatric Surgery (Almaty, the Republic of Kazakhstan).
Results: The presented clinical case demonstrated challenges in
diagnosing and treating young patients with multiple life-threatening
tumor lesions. The need to develop molecular genetic studies and expand diagnostic capabilities is an integral part of treating oncohematological diseases.
Conclusion: The presented clinical case is of great interest due
to its rareness. This case confirms the need to conduct all diagnostic manipulations to assess the process prevalence and to choose and conduct molecular genetic studies on all stages of examination and treatment.