bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phase I study of adjuvant chemotherapy with nab‐paclitaxel and S‐1 for stage III Lauren's diffuse‐type gastric cancer after D2 resection (NORDICA study)
Authors: Cui Yuehong , Yu Yiyi , Yu Shan , Li Wei , Wang Yan , Li Qian , Liu Tianshu 
Published: June 2022

AbstractPurposeThe prognosis of diffuse‐type gastric cancer (DGC) is poorer than that of intestinal type, but S‐1 is a potential treatment option in DGC. This study explored the maximal tolerated dose (MTD) and the recommended dose for phase II study (RP2D) of nab‐paclitaxel combined with S‐1 (AS regimen) as adjuvant chemotherapy in stage III DGC.MethodsPatients with stage III DGC were recruited into this phase I dose‐escalation study between July 2019 and June 2020 in Zhongshan Hospital. Nab‐paclitaxel and S‐1 (80–120 mg/day, d1‐14, q3w) were administrated for 6 cycles, and then 8 cycles of S‐1 monotherapy were applied. The patients received nab‐paclitaxel at 180, 220, or 260 mg/m2 according to the 3 + 3 design based on dose‐limiting toxicity (DLT). The primary endpoint was RP2D. Secondary endpoints were the 1‐year disease‐free survival (DFS) rate and adverse events (AEs).ResultsOne case experienced DLT in 180‐mg/m2 dose group, subsequently three additional subjects were enrolled. DLT was not observed in the 220‐ and 260‐mg/m2 dose groups (both n = 3). Therefore, the MTD has not reached, and the RP2D of nab‐paclitaxel would be 260 mg/m2. Five participants showed progressive disease, with three and two participants in the 180‐ and 220‐mg/m2 dose groups, respectively. The 6‐, 12‐, and 18‐month DFS rates were 100%, 63.6%, and 50.9%, respectively. The most frequently observed AEs were neutropenia (83.3%) and leukopenia (66.7%).ConclusionThe RP2D of nab‐paclitaxel as adjuvant chemotherapy in DGC was 260 mg/m2. The AS regimen had a tolerable AE profile in stage III DGC.
Treatment of gummy smile combining crown lengthening, lip repositioning, and the use of polyester threads
Authors: Horn Renata O. R. , Joly Júlio C. 
Published: June 2022

AbstractIntroductionThe case report presents a new possibility of treatment for a gummy smile in a patient with multiple etiologies, such as altered passive eruption and hypermobility upper lip. At first, crown lengthening was not sufficient to achieve the desired aesthetic result, being necessary its combination with lip repositioning.Case PresentationCrown lengthening surgery (CLS) was performed in a 20‐year‐old woman, with a gingival display of 7.5 mm, having her gingival exposure reduced to 5.5 mm. Because the patient continued unsatisfied after 6 months, a new procedure was adopted. To reduce even more her gingival exposure, lip repositioning technique was performed associated with myotomy and the insertion of polyester threads as a physical barrier to prevent relapse.ConclusionThe result of the gingival display was reduced to 2.5 mm, removing the condition of a gummy smile after the combination of both techniques: crown lengthening, and lip repositioning.Key pointsWhy is this case new information?

Association of the technique of lip repositioning and myotomy, the insertion of polyester threads that act as a physical barrier against recurrence.
What are the keys to successful management of this case?

Correct etiological diagnosis.
Prior application of botulinum toxin.
Respect the period of 1 month for the insertion of the polyester thread, helping to preserve the suture (limitation of movement).
What are the primary limitations to success in this case?

Make the patient aware not to move the lips with the hands in order to observe the incision.
The affect premium for brands: Brand‐first versus attribute‐first presentation of product information impacts willingness to pay
Authors: Narayanan Priya , Sahay Arvind 
Published: June 2022

AbstractDespite considerable difference between brand and attribute information, the question of whether sequential presentation of brand and attribute information can impact product evaluation has yet to be addressed. We answer this question by identifying a novel affect‐based mechanism for sequential presentation of brand and attribute information that is distinct from existing mechanisms that are predominantly cognitive. Based on the affective mental associations for a brand (vs. an attribute), we show that willingness to pay for a product is higher under brand‐first (vs. attribute‐first) presentation, a difference that we term the “affect premium” for brands. We present an affect‐based explanation for this phenomenon by showing that it is observed only for strong brands, mediated by affect elicited by the brand, and observed only under promotion (vs. prevention) focus due to contingent reliance on affect. Further research could determine the information processing pathway involved and boundary conditions for the observed effect.
Psychometric characteristics of the Dutch Personality Assessment Scale in Papiamento‐speaking prisoners
Authors: van de Vorst Micha , Heijtel Frans G. M. , Matroos Glenn M. , Vinkers David J. 
Published: June 2022

AbstractBackgroundAlthough personality disorders are common among offenders, there is no validated translated questionnaire for the assessment of personality disorders in Papiamento, a Portuguese‐Spanish influenced creole language, which is widely spoken on the former Dutch Antilles.AimTo evaluate the Dutch Personality Scale as translated into Papiamento in the prison of Bonaire.MethodsThe Dutch Personality Assessment Scale was translated into Papiamento by two independent experts and retranslated back into Dutch by two other fully bilingual and independent experts. Twenty‐four Papiamento‐speaking prisoners agreed to participate in the study.ResultsThere was good agreement on translation of the assessment items. The prisoner participants reported no difficulties in answering the questions. The internal consistency was acceptable for the seven subscales except for ‘egoism’ (α 0.21) and very good for ‘inadequacy’ and ‘social inadequacy’ (0.88 and 0.82 respectively). The scores of neuroticism, rigidity, egoism and dominance were higher than in the general Dutch population.ConclusionTranslation of the Dutch Personality Scale into the creole language Papiamento proved feasible. The cross‐cultural translation and validation of personality assessment scales may be helpful in assessment of personality disorders in offenders speaking creole languages.
Neonatal lupus erythematosus—a rare syndrome of transient autoimmunity
Authors: Zdraveska Nikolina , Kostovski Aco , Sofijanova Aspazija , Jancevska Snezana , Jovanovska Jana , Kacarska Milena , Damevska Katerina 
Published: June 2022

AbstractNeonatal lupus erythematosus (NLE) is a rare autoimmune disease due to a passive transfer of maternal autoantibodies to the fetus. The clinical spectrum is variable and includes skin lesions, cardiac, hematological, or hepatobiliary disorders. We report an NLE case presenting with skin eruption that was initially considered as tinea.
Transmigration of copper IUCD leading to abdominal abscess: A case report
Authors: Lamichhane Ramesh , Kumari Swati , Khadka Anuska 
Published: June 2022

AbstractFar migrated IUCD (Intrauterine Contraceptive Device) is an uncommon condition that has different manifestations depending upon its location. We present the case of a 22‐year‐old primipara who had a spontaneous abortion after IUCD placement and suffered chronic right lower abdominal pain thereafter. Diagnostic laparoscopy revealed Cu‐IUCD in the right iliac fossa.
Effect of turbulence intensity and surface tension on the emulsification process and its stationary state—A numerical study
Authors: Begemann Alexander , Trummler Theresa , Trautner Elias , Hasslberger Josef , Klein Markus 
Published: June 2022

AbstractWe study turbulent emulsions and the emulsification process in homogeneous isotropic turbulence (HIT) using direct numerical simulations (DNS) in combination with the volume of fluid method (VOF). For generating a turbulent flow field, we employ a linear forcing approach augmented by a proportional‐integral‐derivative (PID) controller, which ensures a constant turbulent kinetic energy for two phase flow scenarios and accelerates the emulsification process. For the simulations, the density ratio of dispersed and carrier phases is chosen to be similar to that of oil and water (0.9), representing a typical application. We vary the turbulence intensity and the surface tension coefficient. Thus, we modulate those parameters that directly affect the Hinze scale, which is expected to be the most stable maximum droplet diameter in emulsions in HIT. The considered configurations can be characterized with Taylor Reynolds numbers in the range of 100–140 and Weber numbers, evaluated with the velocity fluctuations and the integral length scale, of 4–70. Using the 3‐D simulation results, we study the emulsification process as well as the emulsions at a statistically stationary state. For the latter, droplet size distributions are evaluated and compared. We observe a Hinze scale similarity of the size distributions considering a fixed integral length scale, that is, similar Hinze scales obtained at different turbulence intensities or for different fluid properties result in similar distributions.
Recent advances in density functional theory and molecular dynamics simulation of mechanical, interfacial, and thermal properties of natural gas hydrates in Canada
Authors: Mathews Samuel , Daghash Shaden , Rey Alejandro , Servio Phillip 
Published: June 2022

AbstractGas hydrates are inclusion compounds of a water backbone that encloses gaseous molecules. Thanks to their applications in gas recovery, carbon capture and storage, gas storage, and flow assurance, generating high quality data and predictions of their properties is paramount. A review of novel techniques using first principles density functional theory and molecular dynamics simulations methods coupled to auxiliary simulations methods is presented herein. Structure I (sI), structure II (sII), and structure H (sH) hydrates have been studied extensively, with studies of their material strength showing that it is often misleading to use the properties of ice instead of the difficult‐to‐determine gas hydrate properties. Key differences between the three structures and their possible guests are presented. The interfacial properties of gas hydrates display key behaviours that control nucleation and growth, which are important phases in controlling and monitoring their formation. Gas hydrate thermal properties are also examined, with key differences existing between guests and some unusual alignment in the cages shown for carbon dioxide, ethane, and ethylene oxide sI hydrates. First principles infrared spectroscopy is also examined, with techniques showing that these signatures can be tied to and predict material properties to improve the speed of analysis. Therefore, by quantifying, modelling, predicting, and explaining their formation and dissociation, and linking these to their thermal, material, and interfacial properties, a database of reliable data for science and engineering methods and applications is formed to provide a basis for further work.
An efficient hand gesture recognition based on optimal deep embedded hybrid convolutional neural network‐long short term memory network model
Authors: Palanisamy Gajalakshmi , Thangaswamy Sree Sharmila 
Published: June 2022

AbstractHand gestures are the nonverbal communication done by individuals who cannot represent their thoughts in form of words. It is mainly used during human‐computer interaction (HCI), deaf and mute people interaction, and other robotic interface applications. Gesture recognition is a field of computer science mainly focused on improving the HCI via touch screens, cameras, and kinetic devices. The state‐of‐art systems mainly used computer vision‐based techniques that utilize both the motion sensor and camera to capture the hand gestures in real‐time and interprets them via the usage of the machine learning algorithms. Conventional machine learning algorithms often suffer from the different complexities present in the visible hand gesture images such as skin color, distance, light, hand direction, position, and background. In this article, an adaptive weighted multi‐scale resolution (AWMSR) network with a deep embedded hybrid convolutional neural network and long short term memory network (hybrid CNN‐LSTM) is proposed for identifying the different hand gesture signs with higher recognition accuracy. The proposed methodology is formulated using three steps: input preprocessing, feature extraction, and classification. To improve the complex visual effects present in the input images, a histogram equalization technique is used which improves the size of the gray level pixel in the image and also their occurrence probability. The multi‐block local binary pattern (MB‐LBP) algorithm is employed for feature extraction which extracts the crucial features present in the image such as hand shape structure feature, curvature feature, and invariant movements. The AWMSR with the deep embedded hybrid CNN–LSTM network is applied in the two‐benchmark datasets namely Jochen Triesch static hand posture and NUS hand posture dataset‐II to detect its stability in identifying different hand gestures. The weight function of the deep embedded CNN‐LSTM architecture is optimized using the puzzle optimization algorithm. The efficiency of the proposed methodology is verified in terms of different performance evaluation metrics such as accuracy, loss, confusion matrix, Intersection over the union, and execution time. The proposed methodology offers recognition accuracy of 97.86% and 98.32% for both datasets.
The ICD‐11 and DSM‐5‐TR prolonged grief criteria: Validation of the Traumatic Grief Inventory‐Self Report Plus using exploratory factor analysis and item response theory
Authors: Kokou‐Kpolou Cyrille Kossigan , Lenferink Lonneke I. M. , Brunnet Alice Einloft , Park Sunyoung , Megalakaki Olga , Boelen Paul , Cénat Jude Mary 
Published: June 2022

AbstractMore recently, the prolonged grief disorder (PGD) has been recognized as a mental health disorder following bereavement, which is distinct from depression and PTSD. However, the number and proposed symptom items vary across the ICD‐11 and the DSM‐5‐TR criteria for PG. The Traumatic Grief Inventory‐Self Report Plus (TGI‐SR+), which is an updated version of the TGI‐SR, is currently the only robust instrument that assesses PG according to the ICD‐11 and DSM‐5‐TR criteria. For research and clinical use among French‐speaking countries, the forward‐backward procedure was applied to translate the TGI‐SR+ into French language. Exploratory factor analysis and parallel analysis converged towards a two‐dimensional structure for the TGI‐SR+, representing adaptation difficulties and traumatic separation distress. However, items mapping onto ICD‐11 and DSM‐5‐TR criteria for PG represented a one‐dimensional structure. Findings based on item response theory method provided strong evidence for discriminative characteristics of the items. The internal reliability was excellent for the TGI‐SR+ (McDonald's ω = 0.97) and ICD‐11 and DSM‐5‐TR criteria for PGD (McDonald's ω = 0.95). We also demonstrated a very high temporal stability for the TGI‐SR+ total score (ICC = .91, p < 0.0001) and ICD‐11 PGD and DSM‐5‐TR PGD (ICC = 0.90, and ICC = 0.88, ps < 0.0001, respectively). The concurrent validity of the instrument was also demonstrated, such that the TGI‐SR+ total score and all combinations were positively and significantly associated with the levels of depression, anxiety and post‐traumatic stress symptoms. However, the effect sizes were moderate. We conclude that for research and clinical use among French bereaved populations, the TGI‐SR+ is a sound tool with very good psychometric properties.
Building Leadership Skills in Research Groups
Authors: Robel Stefanie 
Published: June 2022

AbstractThe academic research enterprise currently suffers from a culture of “academic bullying” and an unprecedented worldwide mental health crisis among trainees and faculty. These struggles, in part, result from a lack of leadership skills. Mental health, well‐being, intrinsic motivation, and engagement at work are linked to three fundamental needs of self‐determination: autonomy, competence, and relatedness. A great leader will first ensure they are meeting their own needs and, secondly, will support their team members in increasing their needs without decreasing autonomy. This article is a practical “how‐to” guide for researchers at every stage of the academic career path. It distinguishes management from leadership and addresses three key leadership competencies related to the self‐determination needs: 1. Increasing one's personal power as a foundation for autonomy, 2. building a culture of belonging and psychological safety to nurture relatedness, and 3. supporting and encouraging the need for competence by enabling people to self‐evaluate performance and direct professional growth. © 2022 Wiley Periodicals LLC.
Sensemaking factors influencing the engagement in corporate social responsibility
Authors: Bataillard Carole 
Published: June 2022

AbstractThis article analyses the sensemaking factors influencing the corporate social responsibility (CSR) engagement of management students. CSR is a complex enterprise, producing different related goals and consequently ambiguity, significantly restricting individuals' engagement in it. While studying the processes involved in CSR engagement decision‐making is key to understanding why individuals behave differently, these processes have not been extensively researched. To fill this gap, we explore antecedents related to the cognitive processes influencing CSR engagement. The main contribution lies in providing a new typology and the empirical presentation of three sensemaking factors influencing CSR engagement, depending on the value attached to the decision to engage and emotions. The results also describe how ambiguity may discourage CSR engagement, and how the business case approach is enhanced. Overall, this research improves our understanding of antecedents of CSR engagement as well as cognitive and emotional processes shaping CSR evaluations.
Three‐stage transformer‐coupled CMOS power amplifier for millimeter‐wave applications using 130 nm CMOS technology
Authors: Mansour Marwa , Mansour Islam 
Published: June 2022

AbstractHigh‐efficiency and high‐linearity three‐stage transformer‐coupled power amplifier (PA) and power combiner for millimeter‐wave applications using 130 nm CMOS technology are presented in the paper. The suggested PA uses transformer coupled for input, inter‐stage, and output matching networks where the inter‐stage matching inductors are utilized to enhance the RF performance. The proposed power amplifier is composed of three stages: first, driver, and power stages. The first stage operates in a class‐C to improve the efficiency and decrease power dissipated while a class‐AB is used in the driver and power stages to maximize the output power. The proposed PA and power combiner designs are suitable for mm‐wave 5G applications. The coupling transformers, inter‐stage matching inductors, and output combiner are analyzed and designed using Ansoft high‐frequency structure simulator (HFSS) and achieve high‐quality factor and high‐coupling coefficient over the frequency range from 26 to 33 GHz. The proposed three‐stage transformer‐coupled power amplifier covers a frequency band from 26 GHz to 33 GHz with a saturated output power of 13.1 dBm, a peak power added efficiency (PAE) equals 19.1%, and a maximum power gain of 13.25 dB. Whereas the proposed power combiner has a saturated output power of 16.3 dBm, a maximum PAE equals 20.5% and a peak gain of 16.5 dB. The proposed three‐stage transformer‐coupled PA and power combiner consume low power of 65 mW and 128 mW, respectively. Moreover, the adjacent channel power ratios (ACPR) of the proposed PA and power combiner equal −30 dBc and −36 dBc, respectively, for 20 MHz channel bandwidth. Finally, the active areas of the proposed power amplifier and power combiner equal 0.25 mm2 and 0.69 mm2, respectively, while the chip areas are 0.55 mm2 and 1 mm2, respectively.
Pronounced squamous cell contamination in biliary tract cytology: A diagnostic pitfall
Authors: Tomm Nicole K. , Lamps Laura W. , Ko Christopher , Kwon Richard S. , Cantley Richard , Pantanowitz Liron 
Published: June 2022

AbstractSquamous cells are rarely found in biliary tract cytology specimens, and when present are typically scant in quantity. Over an 8‐year time period, two cases at our institution reporting abundant squamous cells were identified. Both patients underwent endoscopic retrograde cholangiopancreatography with bile duct brushings and removal of a migrated biliary stent. The migrated stents were retrieved using rat toothed forceps and required removal of the endoscope through the esophagus with the stent exposed to esophageal and oral mucosa outside of the endoscope. Cytologic examination of the accompanying biliary stent material accordingly revealed abundant benign squamous cells. However, bile duct brushings showed benign ductal epithelial cells without squamous cells. Prior and subsequent cytology and bile duct surgical pathology specimens did not show squamous metaplasia. Migrated biliary stents that require endoscopic withdrawal increase the risk of contaminating samples with squamous cells. Recognition of this unique scenario is important, as the differential diagnosis includes squamous metaplasia and squamous neoplasia.