bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age-Related Model for Estimating the Symptomatic and Asymptomatic Transmissibility of COVID-19 Patients
Authors: Tan Jianbin , Shen Ye , Ge Yang , Martinez Leonardo , Huang Hui 
Published: December 2022

Abstract
Estimation of age-dependent transmissibility of COVID-19 patients is critical for effective policymaking. Although the transmissibility of symptomatic cases has been extensively studied, asymptomatic infection is understudied due to limited data. Using a dataset with reliably distinguished symptomatic and asymptomatic statuses of COVID-19 cases, we propose an ordinary differential equation model that considers age-dependent transmissibility in transmission dynamics. Under a Bayesian framework, multi-source information is synthesized in our model for identifying transmissibility. A shrinkage prior among age groups is also adopted to improve the estimation behavior of transmissibility from age-structured data. The added values of accounting for age-dependent transmissibility are further evaluated through simulation studies. In real-data analysis, we compare our approach with two basic models using the deviance information criterion (DIC) and its extension. We find that the proposed model is more flexible for our epidemic data. Our results also suggest that the transmissibility of asymptomatic infections is significantly lower (on average, 76.45% with a credible interval (27.38%, 88.65%)) than that of symptomatic cases. In both symptomatic and asymptomatic patients, the transmissibility mainly increases with age. Patients older than 30 years are more likely to develop symptoms with higher transmissibility. We also find that the transmission burden of asymptomatic cases is lower than that of symptomatic patients.
A new red alga preserved with possible reproductive bodies from the 518‐million‐year‐old Qingjiang biota
Authors: Li Rui‐Yun , Cui Lin‐Hao , Fu Dong‐Jing , Zhang Xing‐Liang 
Published: December 2022

AbstractMacroalgae have been a key ecological component of marine ecosystems since the Proterozoic period and are common fossil forms in Cambrian Burgess Shale‐type Lagerstätten. However, in most cases, it is difficult to place these early fossil algae into modern groups because little distinctive morphology is preserved. Here, we describe a new form of macroalgae, Qingjiangthallus cystocarpium gen. & sp. nov., from the Qingjiang biota of South China. The new taxon is represented by 546 specimens remarkably preserved with characteristics that allow a phylogenetic placement into crown groups of red algae. Centimeter‐sized thalli resemble members of the extant Rhodymeniophycidae (a subclass of the class Florideophyceae), and hence suggest a florideophycean affinity, which indicates that ahnfeltiophycidaen and rhodymeniophycidaen algae may have diverged at least 518 Ma, accordant with estimations of molecular studies. The presence of possible cystocarps on Qingjiangthallus thalli suggests that evolutionary innovation of a triphasic life cycle in red algae may have occurred no later than the Early Cambrian. The branching patterns and branch width of Qingjiangthallus are consistent with the coarsely dichotomously branched morphogroup, which was previously present in the Ediacaran, Ordovician, and afterward, but absent in the Cambrian.
Deposition of Iodine-125 on Silver Supports of Microsources for Prostate Cancer Brachytherapy
Authors: Shapovalov V. V. , Artamonov S. A. , Eldashev N. V. , Kutin A. Yu. , Nerozin N. A. , Podsoblyaev D. A. , Samsonov M. D. , Togaeva N. R. , Tkachev S. V. 
Published: December 2022

Abstract
A method of iodine-125 deposition on a surface of microsource silver supports for brachytherapy of prostate cancer was reported, which includes preparing the support surface by sequentially treating them with nitric acid and thiourea solutions, followed by chlorination of the support surface with a chlorinating agent to form silver chloride on the support surface, and substitution of chlorine atoms for 125I atoms by placing supports containin silver chloride on the surface in a solution with 125I ions to create a 125I layer on the support surface. The method described allows fixing 125I on supports with a low activity distribution on each activity-carrying support.
On the sensitivity of the D parameter to new physics
Authors: Falkowski Adam , Rodríguez-Sánchez Antonio 
Published: December 2022

AbstractMeasurements of angular correlations in nuclear beta decay are important tests of the Standard Model (SM). Among those, the so-calledDcorrelation parameter occupies a particular place because it is odd under time reversal, and because the experimental sensitivity is at the$$10^{-4}$$10-4level, with plans of further improvement in the near future. Using effective field theory (EFT) techniques, we reassess its potential to discover or constrain new physics beyond the SM. We provide a comprehensive classification of CP-violating EFT scenarios which generate a shift of theDparameter away from the SM prediction. We show that, in each scenario, a shift larger than$$10^{-5}$$10-5is in serious tension with the existing experimental data, where bounds coming from electric dipole moments and LHC observables play a decisive role. The tension can only be avoided by fine tuning of the parameters in the UV completion of the EFT. We illustrate this using examples of leptoquark UV completions. Finally, we comment on the possibility to probe CP-conserving new physics via theDparameter.
Estrogen-DNA Adducts and Breast Cancer Risk in Premenopausal Asian Women
Authors: Lin Ching-Hung , Zahid Muhammad , Kuo Wen-Hung , Hu Fu-Chang , Wang Ming-Yang , Chen I-Chun , Beseler Cheryl L. , Mondal Bodhisattwa , Lu Yen-Shen , Rogan Eleanor G. , Cheng Ann-Lii 
Published: December 2022

AbstractThe incidence of breast cancer among premenopausal women has been increasing rapidly in recent decades in East Asia. This case–control study investigated whether estrogen-DNA adducts were associated with breast cancer risk in Taiwan. The control group (n = 146) comprised healthy female volunteers and women with non-proliferative breast disease. The case group (n = 221) comprised women either with proliferative benign breast disease or breast cancer. The ratios of estrogen-DNA adducts to their respective metabolites and conjugates in plasma were analyzed using ultraperformance LC/MS-MS. The SNPs of CYP1A1, CYP1B1, and COMT were genotyped. Logistic regression model was used to compare the estrogen-DNA adduct ratios between the two groups. The estrogen-DNA adduct ratio in the case group was significantly higher than that in the control group (median ratio: 58.52 vs. 29.36, P = 0.004). A multiple logistic regression model demonstrated that a unit increase in the natural log of the estrogen-DNA adduct ratio in premenopausal women was a significant predictor of breast cancer risk, with an estimated hazard ratio of 1.718 (1.444−2.046, P &lt; 0.001). However, the CYP1A1, CYP1B1, and COMT SNPs were not associated with the estrogen-DNA adduct ratios. In conclusion, plasma estrogen-DNA adduct ratio was associated with the presence of breast cancer or proliferating benign breast disease in premenopausal women in Taiwan.Prevention Relevance:This study provides evidence that endogenous estrogen-induced genotoxicity may contribute to the carcinogenesis of breast cancer in premenopausal Asian women. This work could have important preventive implication for the emerging disease in East Asia.
Onception: Active Learning with Expert Advice for Real World Machine Translation
Authors: Mendonça Vânia , Rei Ricardo , Coheur Luísa , Sardinha Alberto 
Published: December 2022

Abstract
Active learning can play an important role in low-resource settings (i.e., where annotated data is scarce), by selecting which instances may be more worthy to annotate. Most active learning approaches for Machine Translation assume the existence of a pool of sentences in a source language, and rely on human annotators to provide translations or post-edits, which can still be costly. In this article, we apply active learning to a real-world human-in-the-loop scenario in which we assume that: (1) the source sentences may not be readily available, but instead arrive in a stream; (2) the automatic translations receive feedback in the form of a rating, instead of a correct/edited translation, since the human-in-the-loop might be a user looking for a translation, but not be able to provide one. To tackle the challenge of deciding whether each incoming pair source–translations is worthy to query for human feedback, we resort to a number of stream-based active learning query strategies. Moreover, because we do not know in advance which query strategy will be the most adequate for a certain language pair and set of Machine Translation models, we propose to dynamically combine multiple strategies using prediction with expert advice. Our experiments on different language pairs and feedback settings show that using active learning allows us to converge on the best Machine Translation systems with fewer human interactions. Furthermore, combining multiple strategies using prediction with expert advice outperforms several individual active learning strategies with even fewer interactions, particularly in partial feedback settings.
Politicizing Algorithms by Other Means: Toward Inquiries for Affective Dissensions
Authors: Jaton Florian , Vinck Dominique 
Published: December 2022

AbstractIn this paper, we build upon Bruno Latour’s political writings to address the current impasse regarding algorithms in public life. We assert that the increasing difficulties at governing algorithms—be they qualified as “machine learning,” “big data,” or “artificial intelligence”—can be related to their current ontological thinness: deriving from constricted views on theoretical practices, algorithms’ standard definition as problem-solving computerized methods provides poor grips for affective dissensions. We then emphasize on the role historical and ethnographic studies of algorithms can potentially play in the politicization of algorithms. By both digging into the genealogy of algorithms’ constricted definition and by making their contemporary constitutive relationships more visible, both historical and ethnographic studies can contribute to vascularizing algorithms and making them objects of enlarged disputes. We conclude by giving a flavor of the political potential of the vascularization efforts we call for, using materials from an ethnographic study conducted in a computer science laboratory.
An Assessment of the National Water Model’s Ability to Reproduce Drought Series in the Northeastern United States
Authors: Wan Tong , Covert Brenden H. , Kroll Charles N. , Ferguson Craig R. 
Published: December 2022

Abstract
Portions of the northeastern United States (NE) have experienced drought every year since 2016. The U.S. Drought Monitor (USDM) has played an important role in drought characterization and management by providing weekly drought maps across the entire United States, including the NE. Unfortunately, the USDM lacks consistency between input variables leading to difficulties in defining boundaries between drought categories. This paper evaluates the National Water Model’s (NWM) ability to model streamflow and soil moisture, two important hydrological products that are frequently incorporated in drought indices. Using a 26-yr NWM retrospective simulation, comparisons were conducted between NWM output and observations of streamflow and soil moisture, as well as between drought categories derived from the NWM and observations and the USDM. Results indicate that NWM provides moderate predictions of streamflow at NE stations when comparing to historical observations, that NWM streamflow estimators are generally upwardly biased, and performance is worse at lower streamflow magnitudes. The NWM’s ability to predict soil moisture is worse than streamflow, with again a positive bias at most sites and strong variations in anomaly correlation across sites. When predicting drought categories, NWM streamflow is as strong a predictor of USDM drought categories as observed streamflow. Extending the NWM streamflow series using a maintenance of variance technique and only past records provides slight improvements over drought categories derived from the entire 26-yr retrospective simulation. Output from the NWM appears to have some skill in characterizing drought in the NE and provides a spatial resolution to improve the designation of drought boundaries.
Institutional Reforms and Spatial Efficiency in Agricultural Supply Chains in India
Authors: Ghosh Madhusudan 
Published: December 2022

This paper reviews the institutional reforms in agricultural commodity markets in India and examines their implications for spatial efficiency in supply chains of the markets. In order to remove inefficiencies in the traditional supply chain, the Agricultural Produce Marketing Committee (APMC) Act was revised, and a Model APMC Act 2003 was introduced with the provisions for establishing private markets/yards, direct purchase centres, farmers markets for direct sale, contract farming and promotion of public–private partnership in the management and development of agricultural markets. Initiative has been taken to set up a National Agricultural Market as an all-India electronic trading portal to develop a ‘common national market’ for agricultural commodities. The institutional reforms in agricultural marketing system since the early 1990s appear to have contributed towards improving the spatial efficiency in rice and wheat markets. The finding of an increase in the extent of spatial integration of markets after the reforms and the tendency of the prices to move towards a common stochastic trend lend support to the idea of setting up a ‘common national market’ for agricultural commodities. Further reforms in the marketing system with better infrastructure facilities would strengthen market integration and improve efficiency in the supply chains. JEL classification: O13, Q13, Q18.
Relationship of Conflict, Conflict Avoidance, and Conflict Resolution to Psychological Adjustment
Authors: Bruce Madeline J. , Chang Alexander , Evans Luke , Streb Madison , Dehon Jewell , Handal Paul J. 
Published: December 2022

Background: Conflict has deleterious effects on the adjustment of children, adolescence, and emerging adults. The literature is less robust on the adverse effects of conflict avoidance on adjustment as well as the beneficial effect of resolution in these age groups. The literature is markedly sparser on these relationships in adults. Method: We recruited N = 1471 US adults between 18 and 86 years old ( M = 33.94, SD = 11.67). They primarily identified as White with 51% holding at least a bachelor’s degree. Participants responded to the Perceived Family Conflict Subscale, Avoidant Conflict Scale, the Family Conflict Resolution Scale, and the Langner Symptom Survey. Results: A MANOVA modeling the four variables demonstrated a significant difference based on sex for the measure of distress and need for treatment ( Mwomen = 5.31, Mmen = 3.93, p < .001). Separate analyses for men and women yielded the same pattern for each sex. Specifically, low conflict groups, as well as low conflict avoidance groups, scored significantly lower on a measure of distress than the high conflict and conflict avoidance group. For conflict resolution, the high groups scored significantly lower on distress than did the low resolution group. Discussion: The deleterious effect of conflict and conflict avoidance were found in both adult men and women, thereby extending results found in children, teens, and young adults. Similarly, the beneficial effect of conflict resolution manifest in adult men and women, which had been found in young adults. Interventions aimed at reducing conflict avoidance and increasing conflict resolution skills should theoretically reduce stress.
Effect of pneumatic compression device and stocking use on symptoms and quality of life in women with lipedema: A proof-in-principle randomized trial
Authors: Wright Thomas , Scarfino Crystal D. , O’Malley Ellen M. 
Published: December 2022

Objective Does short-term use of pneumatic compression devices (PCD) and off-the-shelf compression alleviate symptoms and improve quality of life in women with lipedema and secondary lipolymphedema? Methods Prospective, randomized controlled, industry-sponsored, proof-in-principle study comparing PCD plus conservative care (PCD+CC) to CC alone (control). Adult females with bilateral lipedema and secondary lymphedema were randomized to PCD+CC or CC. Outcome measures were lower limb and truncal circumferential measurements, bioimpedance, and quality-of-life, symptom, and pain intensity questionnaires. Results Both groups experienced improvements in leg circumference and bioimpedance with more improvement in the PCD+CC group than the CC group. Pain scores of the SF-36 survey and numerical rating scales were improved in the PCD+CC group. Wong–Baker Faces scores showed trends toward improvement in both groups. Conclusions This proof-in-principle study supports conservative management with graduated compression and with or without PCD for improvement in leg circumference, bioimpedance measurements, and pain in patients with lipedema.
Presumed sympathetic ophthalmia following scleral buckling surgery: A case report and review of the literature
Authors: Lucchini Sara , Govetto Andrea , Carini Elisa , Casalino Giuseppe , Donati Simone , Radice Paolo 
Published: December 2022

Purpose To report a case of presumed sympathetic ophthalmia (SO) following scleral buckling (SB) surgery and to discuss the possible pathogenesis of this condition by reviewing the current evidence on this subject. Methods Case report and narrative review of the literature; our case was imaged with spectral-domain optical coherence tomography (SD-OCT) and optical coherence tomography angiography (OCTA), fundus autofluorescence (FAF), fluorescein angiography (FFA) and indocyanine green angiography (ICGA). Results A 55-year-old man presented with a macula on rhegmatogenous retinal detachment which was treated with 360° SB surgery, subretinal fluid drain (SRFD), cryopexy and pneumoretinopexy. Due to failure of the primary surgery, a second procedure was performed the day after with the explant of the prior buckle and the implant of a wider circumferential element. At three months from surgery, the patient complained of severe bilateral vision loss. Multimodal imaging revealed bilateral, multi-focal exudative retinal detachments and choroidal swelling. A diagnosis of presumed SO was made and the patient was treated with a combination of steroid and immunosuppressive drugs. The clinical picture completely resolved at postoperative month 12. Conclusion SO may be a rare complication of SB surgery. In our case, early recognition and prompt immunosuppressive treatment achieved good long-term clinical results.
Visual symptoms in a patient treated with MEK inhibitors
Authors: Tibaldi Tommaso , Roccuzzo Gabriele , Fazio Alessandra , Cattani Ilaria , Nuzzi Raffaele , Quaglino Pietro , Reibaldi Michele 
Published: December 2022

Purpose to report an uncommon presentation of Encorafenib-Binimetinib retinal side effects Case report A 56-year-old Caucasian woman, naïve to previous chemotherapies, was started on Encorafenib/Binimetinib for metastatic melanoma. After seven hours from the first 45 mg Binimetinib dose, the patient developed blurry vision with coloured halos. The symptoms were transient and the following day a complete ophthalmological examination revealed the presence of subretinal fluid (SRF) at Optical coherence tomography (OCT). After one week, the patient remained asymptomatic, with no signs of SRF at the follow up reevaluation. However, six weeks later, the symptoms originally experienced with the first drug intake appeared again. This time fundus examination revealed an irregular macular region. At infrared OCT an almond shaped hyporeflective lesion, surrounded by hyperreflectivity, was demonstrated without signs of SRF. Encorafenib/Binimetinib was continued at the same dose and strict monitoring was scheduled, according to the European Medicine's Agency indication to withhold the drug only in presence of symptomatic retinal pigment epithelial detachment. Conclusion Visual symptoms associated with SRF induced by Binimetinib have been described in the literature. In our case, visual symptoms were experienced by the patient at different times, both with and without evidence of SRF. This finding seems to suggest that while Binimetinib-induced SRF is an asymptomatic finding in most cases, with excellent outcome and rapid resolution, visual symptoms could be initially triggered by detectable SRF, yet persist without any further evidence of abnormal fluid accumulation and manifest intermittently.
Explicit stigma and implicit biases toward autism in South Korea versus the United States
Authors: Kim So Yoon , Cheon Jeong Eun , Gillespie-Lynch Kristen , Grandits Jennifer , Kim Young-Hoon 
Published: December 2022

This cross-cultural study examined Koreans’ and Americans’ explicit stigma and implicit biases toward autism to examine potential mechanisms underlying recent evidence for heightened explicit autism stigma in South Korea relative to the United States. This evidence is somewhat at odds with other evidence that individuals living in collectivistic cultures such as South Korea may be more prone to present themselves favorably than those living in relatively individualistic cultures such as the United States. A total 224 American and 536 Korean non-autistic adult participants completed an online survey. Implicit biases were measured using the implicit association test. Koreans reported greater explicit stigma and exhibited more implicit biases toward autism than Americans. Explicit stigma was not correlated with implicit biases in either country. Less autism knowledge and pleasant contact with autistic people predicted greater explicit stigma among both Koreans and Americans. Less frequent contact and heightened assimilation ideology toward ethnic minorities predicted greater stigma only among Koreans. The variance in implicit biases explained by predictors was small, emphasizing the need for follow-up research investigating predictors of implicit biases. Informing Koreans about the shortcomings of assimilationist approaches and fostering an appreciation of the plurality of cultures may reduce stigma toward autistic individuals in South Korea. Lay abstract How people report their feelings about autism may be different from how they actually think about autism because some people may not want to reveal their true feelings. People who value the group’s goal tend to present themselves as more socially acceptable than people who value one person’s interests. We studied how people in South Korea and the United States report their feelings about autism and think about autism. Koreans tend to value the group’s goals. Americans tend to prefer one person’s goals. Koreans reported that they wanted more space from autistic people than Americans did. Koreans were more likely to think about autism with negative words (and think more negatively about autism). How Koreans and Americans report their feelings about autism was not related to their thoughts about autism. People who knew about autism and liked meeting with autistic people wanted to get closer to autistic people in South Korea and the US, Koreans who had met autistic people and thought that people who newly came to Korea from abroad should be more like Koreans did not want to get very close to autistic people. This could be because very few foreign people live in South Korea compared to the United States. Teaching Koreans that all cultures have values and should be appreciated will help them like autistic people more.