bluuebunny/crossref_metadata_2025_split huggingface dataset:
Main street business owners: aging in plain sight
Authors: Forster-Holt Nancy 
Published: December 2021

PurposeAging is the most important social-demographic issue worldwide, supported by the initiatives of the World Health Organization (WHO) in its global strategy and action plan for aging and health (Rudnicka et al., 2020). The average age of business owners in most industrialized countries is on the rise. In the United States, fifty-one percent of small private businesses are owned by someone age fifty-plus (SBA Office of Advocacy, 2018).Design/methodology/approachThe authors shed light on small business owners, who age in place. The authors suggest that their importance as long-term actors in entrepreneurial ecosystems nor the issue of “Main Street churn” have not been meaningfully explored. Understanding the risks they face offers an opportunity for academics and practitioners to provide insights for business owners, the next generation of the acquirer and advisors. The coronavirus disease 2019 (COVID-19) pandemic has elevated the status of many of these businesses from invisible (and perhaps taken for granted) to “essential” and amplified the co-dependence of business and the local economy.Findings The anticipated “silver tsunami” caused by the retirements of Main Street business owners is not a national and homogeneous wave. Rather, each wave will land on beaches locally. Small business owners age in place, and their importance as long-term actors in entrepreneurial ecosystems nor the issue of “Main Street churn” have not been meaningfully explored. They become embedded in their community and possibly stuck there in retirement.Originality/value The embeddedness of these owners – who likely have social connections, community identification and feelings of responsibility to the community directly impacts the places that they care deeply about – is often unquestioned. However, their retirements call for increased visibility within entrepreneurial ecosystems and translations of scholarly work from several kinds of literature into policy and practice.
Dual crossover mechanisms of benevolent supervision on followers' contextual performance and emotional exhaustion alleviation
Authors: Chuang Ya-Ting , Chiang Hua-Ling , Lin An-Pan , Lien Yung-Chih 
Published: December 2021

PurposeAdopting conservation of resources (COR) theory as a guiding framework, this study proposes that benevolent supervision (BS) is a feasible leadership style for building a positive resource gain process in subordinates' extra-role actions and reducing their exhaustion, and leader-member exchange (LMX) and positive affect (PA) serve as indirect crossover mechanisms.Design/methodology/approachSurveys were conducted at three-time points with four-week intervals. A total of 304 subordinates and 55 supervisors at a Taiwanese university participated in the surveys, and a multilevel model was used to test the hypotheses.FindingsThe results showed that prior BS (time 1) was positively associated with subordinates' subsequent LMX and PA (time 2). LMX mediated the relationship between BS and subsequent supervisor-rated contextual performance (time 3), and PA mediated the relationship between BS and subordinate-rated emotional exhaustion (time 3). In addition, supervisors' learning orientation positively moderated the relationship between BS and contextual performance via LMX, whereas supervisors' performance orientation negatively moderated this relationship.Practical implicationsThe results of the study encourage leaders to exhibit benevolence toward subordinates, increase subordinates' contextual performance and enhance personal feelings, thereby ultimately benefitting the organization.Originality/valueThis study reveals that BS is a source of resource investment in the process of subordinates' positive job (contextual performance) and personal (emotional exhaustion) resource gains through social exchange (LMX) and affective (PA) crossover mechanisms and that supervisors' goal inclinations impact this process.
Impact of high pressure processing on microbiological, nutritional and sensory properties of food: a review
Authors: Amsasekar Ajith , Mor Rahul S. , Kishore Anand , Singh Anupama , Sid Saurabh 
Published: January 2022

Purpose
The increased demand for high-quality, nutritionally rich processed food has led to non-thermal food processing technologies like high pressure processing (HPP), a novel process for microbial inactivation with minimal loss of nutritional and sensory properties. The purpose of this paper is to highlight the impact of HPP on the microbiological, nutritional and sensory properties of food.

Design/methodology/approach
Recent research on the role of HPP in maintaining food quality and safety and the impact of process conditions with respect to various food properties have been explored in this paper. Also, the hurdle approach and the effectiveness of HPP on food quality have been documented.

Findings
HPP has been verified for industrial application, fulfilling the consumer demand for processed food with minimum nutrition loss at low temperatures. The positive impact of HPP with other treatments is known as the hurdle approach that enhances its impact against microorganism activity and minimizes the effects on nutrition and sensory attributes.

Originality/value
This paper highlights the impact of HPP on various food properties and a good alternative as non-thermal technology for maintaining shelf life, sensory properties and retention of nutrients.
Forecasting the efficiency of weft knitting production: a decision tree method
Authors: Le Song Thanh Quynh , Ho June , Bui Huong Mai 
Published: December 2021

Purpose
This paper aims to develop a decision support system for predicting the knitting production’s efficiency based on the input parameters of an order. This tool supports the operations managers to make reliable decisions of estimated delivery time, which will result in reducing waste arising from late delivery, overtime and increased labor.

Design/methodology/approach
The decision tree method with a set of logical IF-THEN rules is used to determine the knitting production’s efficiency. Each path of the decision tree represents a rule of the following form: “IF <Condition> THEN <Efficiency label>.” Starting with identifying and categorizing input specifications, the model is then applied to the observed data to regenerate the results of efficiency into classification instances.

Findings
The production’s efficiency is the result of the interaction between input specifications such as yarn’s component, knitting fabric specifications and machine speed. The rule base is generated through a decision tree built to classify the efficiency into five levels, including very low, low, medium, high and very high. Based on this, production managers can determine the delivery time and schedule the manufacturing planning more accurately. In this research, the correct classification instances, which is simply a ratio of the correctly predicted observations to the total ones, reach 80.17%.

Originality/Values
This research proposes a new methodology for estimating the efficiency of weft knitting production based on a decision tree method with an application of real data. This model supports the decision-making process of the estimated delivery time.
Intraspecific interaction of host plants leads to concentrated distribution of a specialist herbivore through metabolic alterations in the leaves
Authors: Ohsaki Haruna , Miyagi Atsuko , Kawai‐Yamada Maki , Yamawo Akira 
Published: December 2021

Abstract

Recent studies suggest that changes in leaf traits due to interactions between plants affect resource utilisation by herbivores, as well as herbivore distribution. However, this has not yet been confirmed experimentally. Here, we investigated the effects of phenotypic plasticity in leaf traits of Rumex obtusifolius (host plant) in response to intraspecific and interspecific interactions on the distribution of two leaf beetles, Gastrophysa atrocyanea (specialist herbivore) and Galerucella grisescens (generalist herbivore).

We investigated the local population density of R. obtusifolius plants and the presence of leaf beetles on the plants at five study sites. Leaf chemicals (condensed tannins and total phenolics) were compared between aggregated and solitary R. obtusifolius plants. To clarify the effects of the interaction environment of R. obtusifolius plants on their leaf traits and on resource utilisation by the leaf beetles, we compared leaf chemicals and preferences of adult leaf beetles among treatments where R. obtusifolius experienced intraspecific interaction, interspecific interaction or no interaction in cultivation experiments. Finally, we evaluated the independent and combined effects of patch size and intraspecific interaction on leaf beetle distribution in mesocosm experiments.

In the field, the presence of the specialist leaf beetle G. atrocyanea was positively correlated with the local population density (rosette overlap ratio) of R. obtusifolius plants; however, there was no correlation in the case of the generalist leaf beetle G. grisescens. In the cultivation experiments, plants in the intraspecific interaction treatment increased their leaf concentrations of condensed tannins and total phenolics, and G. atrocyanea consumed more of these leaves than leaves in other treatments. Similar results were observed in the field. In the mesocosm experiments, larger numbers of G. atrocyanea were distributed on R. obtusifolius plants exposed to below‐ground intraspecific interaction than on plants not exposed to intraspecific interaction.

Our results provide experimental evidence that leaf‐trait changes in response to intraspecific interaction between host plants influence specialist herbivore distribution. This highlights the need to integrate plant–plant interactions into our understanding of plant–animal interactions.

A free Plain Language Summary can be found within the Supporting Information of this article.
Comparative genomics and proteomics of Eubacterium maltosivorans: functional identification of trimethylamine methyltransferases and bacterial microcompartments in a human intestinal bacterium with a versatile lifestyle
Authors: Feng Yuan , Bui Thi Phuong Nam , Stams Alfons J. M. , Boeren Sjef , Sánchez‐Andrea Irene , de Vos Willem M. 
Published: January 2022

SummaryEubacterium maltosivorans YIT is a human intestinal isolate capable of acetogenic, propionogenic and butyrogenic growth. Its 4.3‐Mb genome sequence contains coding sequences for 4227 proteins, including 41 different methyltransferases. Comparative proteomics of strain YIT showed the Wood–Ljungdahl pathway proteins to be actively produced during homoacetogenic growth on H2 and CO2 while butyrogenic growth on a mixture of lactate and acetate significantly upregulated the production of proteins encoded by the recently identified lctABCDEF cluster and accessory proteins. Growth on H2 and CO2 unexpectedly induced the production of two related trimethylamine methyltransferases. Moreover, a set of 16 different trimethylamine methyltransferases together with proteins for bacterial microcompartments were produced during growth and deamination of the quaternary amines, betaine, carnitine and choline. Growth of strain YIT on 1,2‐propanediol generated propionate with propanol and induced the formation of bacterial microcompartments that were also prominently visible in betaine‐grown cells. The present study demonstrates that E. maltosivorans is highly versatile in converting low‐energy fermentation end‐products in the human gut into butyrate and propionate whilst being capable of preventing the formation of the undesired trimethylamine by converting betaine and other quaternary amines in bacterial microcompartments into acetate and butyrate.
Professionalism in the era of accountability: Role discrepancy and responses among teachers in the Netherlands
Authors: Browes Natalie , Altinyelken Hülya K. 
Published: January 2022

AbstractThe roles and identities of professionals have undergone significant transformation in an ever‐globalising world shaped by neoliberal values. In the field of education, standardisation and outcome‐based quality measures have become the norm. Teachers are held accountable through their students’ results, with their work subject to ongoing surveillance (performance‐based accountability). This has changed the nature of teachers’ tasks, and what it means to be a "good teacher". Based on 20 teacher interviews across six primary schools in the Netherlands, this study examines teachers’ practices and beliefs, asking: do they experience role discrepancy? What responses do we see as a result? And, what does this reveal about teachers' sense of professionalism today? Findings show that all teachers experience the pressure of high workloads and the need to prioritise tasks. Whereas a small minority of respondents understand performative tasks as having a crucial function of supporting student learning and achievement, others experienced a discrepancy between these performative tasks and the tasks they believed to be at the heart of good teaching. Confronted with this, teachers responded in different ways; either incorporating all tasks into their schedule, or feeling forced to choose between them. Beyond this, findings indicate that teachers' understandings of key aspects of the profession, such as autonomy, are changing in response to the policy environment. This supports conceptualisations of professions and professionalism as not only "being changed by" external reform, but changing from within.
The economic burden of systemic sclerosis—A systematic review
Authors: Chen Yongcong , Wu Lin , J. Hernández‐Muñoz Jose , J. Miller Michael , Pope Melinda , Huyan Yidan , Zhong Lixian 
Published: December 2021

AbstractAimSystemic sclerosis (SSc) is a rare, chronic autoimmune disease associated with a substantial economic burden. This study aimed to assess the costs associated with SSc and to identify major cost drivers.MethodsA systematic search was conducted in MEDLINE and Embase to identify relevant studies. Two independent reviewers evaluated studies based on inclusion/exclusion criteria and performed data extraction. Costs were converted into 2017 US dollars by purchasing power parity. The review was conducted following the Preferred Reporting Items for Systematic Review and Meta‐analysis (PRISMA) guideline.ResultsThe original literature search identified 113 potentially relevant citations, of which 10 articles met all the inclusion/exclusion criteria and were included in the data extraction and analysis. The identified studies evaluated costs associated with SSc in 11 countries from North America, Europe, and Australia published between 2009 and 2018. Eight studies reported direct costs and seven studies reported indirect costs. Direct costs varied from $3356 (Hungary) to $27 032 (Germany) with hospitalization and medication being two of the biggest components of direct medical costs in most studies. The indirect costs for lost productivity varied from $2433 (Italy) to $20 663 (UK), accounting for a significant portion of the total economic burden.ConclusionsLarge variations existed in annual costs of SSc, but all studies found that SSc imposed a substantial economic burden on patients and their families. The identified studies were mostly from high‐income countries and there is still a knowledge gap regarding the cost of SSc in other parts of the world.
Editorial: bezafibrate in the treatment of patients with primary biliary cholangitis—are we there yet?
Authors: Rodrigues Pedro M. , Banales Jesus M. 
Published: December 2021

LINKED CONTENTThis article is linked to Sorda et al papers. To view these articles, visit https://doi.org/10.1111/apt.16618 and https://doi.org/10.1111/apt.16726
Editorial: subcutaneous CT‐P13 in Crohn’s disease and ulcerative colitis—small change, big consequences
Authors: Carbonnel Franck , Meyer Antoine 
Published: December 2021

LINKED CONTENTThis article is linked to Hanzel et al papers. To view these articles, visit https://doi.org/10.1111/apt.16609 and https://doi.org/10.1111/apt.16724
Editorial: subcutaneous CT‐P13 in Crohn’s disease and ulcerative colitis–small change, big consequences. Authors' reply
Authors: Hanzel Jurij , Bukkems Laura H. , Gecse Krisztina B. , D’Haens Geert R. , Mathôt Ron A. A. 
Published: December 2021

LINKED CONTENTThis article is linked to Hanzel et al papers. To view these articles, visit https://doi.org/10.1111/apt.16609 and https://doi.org/10.1111/apt.16709
Editorial: bezafibrate in the treatment of patients with primary biliary cholangitis—are we there yet? Authors' reply
Authors: Sorda Juan Antonio , González Ballerga Esteban , Barreyro Fernando Javier , Daruich Jorge 
Published: December 2021

LINKED CONTENTThis article is linked to Sorda et al papers. To view these articles, visit https://doi.org/10.1111/apt.16618 and https://doi.org/10.1111/apt.16657
Factors influencing mock parole board members: the impact of an incarcerated person's race/ethnicity, conversion while in prison, and mental health status
Authors: ElBassiouny Amanda , Ayala Rachel , Sircy Kayla 
Published: December 2021

AbstractThe purpose of the current study was to explore how an incarcerated person's race/ethnicity, mental health status, and the type of conversion/lifestyle change experienced in prison would impact a mock parole board member's decisions, perceptions, and emotional reactions. A total of 720 MTurk participants were randomly assigned to read a case file summary of an incarcerated person that varied by his race/ethnicity (White/Black/Arab/Latino), mental health status (no mental health issues/diagnosed with schizophrenia), and the type of conversion/lifestyle change experienced while in prison (Christianity/Islam/atheism/secularism). Participants then responded to items relating to their decision to grant or deny parole, recidivism and rehabilitation, and their perceptions and emotional reactions toward the incarcerated person. It was found that when the incarcerated person converted to Christianity or had a secular lifestyle change, he was perceived more positively than when he converted to atheism. Also, he was perceived more positively if he had no mental illness rather than being diagnosed with schizophrenia. Participants also felt more empathy toward the incarcerated person when he was Black rather than Latino. These factors did impact the perceptions and emotional reactions of mock parole board members.
Tryptophan 2,3‐dioxygenase 2 plays a key role in regulating the activation of fibroblast‐like synoviocytes in autoimmune arthritis
Authors: Chang Yan , Han Ping , Wang Yueye , Jia Chengyan , Zhang Bingjie , Zhao Yingjie , Li Susu , Li Siyu , Wang Xinwei , Yang Xuezhi , Wei Wei 
Published: December 2021

Background and PurposeAbnormal kynurenine (Kyn) metabolism has been closely linked to the pathogenesis of rheumatoid arthritis (RA). The aims of this study were to investigate the role of tryptophan 2,3‐dioxygenase 2 (TDO2), a rate‐limiting enzyme that converts tryptophan (Trp) to Kyn, in regulating fibroblast‐like synoviocyte (FLS)‐mediated synovial inflammation in autoimmune arthritis.Experimental ApproachThe expression of TDO2 was determined by immunohistochemistry, confocal laser scanning fluorescence microscopy, imaging flow cytometry and Western blot. TDO2 activity was tested by HPLC and colorimetric assay. TDO2 siRNA and TDO2 inhibitor 680C91 were used to inhibit TDO2 in AA‐FLS function in vitro. A rat model of adjuvant‐induced arthritis (AA) was used to evaluate the in vivo effect of allopurinol (Allo), a TDO2 inhibitor.Key ResultsTDO2 expression was strongly increased in synovial tissue and FLS of RA and AA. Immune cells were found to express high amount of TDO2 proteins at the peak stage of AA. Pharmacological inhibition or knockdown of TDO2 in AA‐FLS resulted in a reduced proliferation, secretion, migration and invasion. Kyn restored the inhibitory effect of TDO2 inhibition on activation of AA‐FLS. Allo treatment ameliorated the arthritis severity and decreased the activity of TDO2.Conclusion and ImplicationsOur results suggest that elevated TDO2 expression may contribute to synovial inflammation and joint destruction during arthritis. Therefore, targeting TDO2 activity and the Kyn pathway of Trp degradation may represent a potential therapeutic strategy in RA.
Quantifying Talker Variability in North‐American Infants' Daily Input
Authors: Bulgarelli Federica , Mielke Jeff , Bergelson Elika 
Published: December 2021

AbstractWords sound slightly different each time they are said, both by the same talker and across talkers. Rather than hurting learning, lab studies suggest that talker variability helps infants learn similar sounding words. However, very little is known about how much variability infants hear within a single talker or across talkers in naturalistic input. Here, we quantified these types of talker variability for highly frequent words spoken to 44 infants, from naturalistic recordings sampled longitudinally over a year of life (from 6 to 17 months). We used non‐contrastive acoustic measurements (e.g., mean pitch, duration, harmonics‐to‐noise ratio) and holistic measures of sound similarity (normalized acoustic distance) to quantify acoustic variability. We find three key results. First, pitch‐based variability was generally lower for infants' top talkers than across their other talkers, but overall acoustic distance is higher for tokens from the top talker versus the others. Second, the amount of acoustic variability infants heard could not be predicted from, and thus was not redundant with, other properties of the input such as the number of talkers or tokens, or proportion of speech from particular sources (e.g., women, children, electronics). Finally, we find that patterns of pitch‐based acoustic variability heard in naturalistic input were similar to those found with in‐lab stimuli that facilitated word learning. This large‐scale quantification of talker variability in infants' everyday input sets the stage for linking naturally occurring variability “in the wild” to early word learning.
Autonomic nervous system activity in primary Raynaud's phenomenon: Heart rate variability, plasma catecholamines and [123I]MIBG heart scintigraphy
Authors: Lindberg Lotte , Brinth Louise S. , Bergmann Marianne L. , Kristensen Bent , Hansen Tine W. , Hasbak Philip , Thomsen Jane F. , Eldrup Ebbe , Jensen Lars T. 
Published: December 2021

AbstractBackground and AimPrimary Raynaud's phenomenon (pRP) is characterized by an exaggerated response to cold, resulting in the whitening typically of the fingers and toes. The patients are generally perceived as healthy individuals with a benign condition. However, the condition has been associated with increased cardiovascular mortality and changes in autonomic nervous system activity. This study aimed to investigate whether pRP is associated with pervasive changes in autonomic nervous activity. The hypothesis was that patients with pRP have increased sympathetic nervous activity.MethodsThe autonomic nervous activity of 22 patients with pRP was investigated by means of heart rate variability (HRV) and the plasma catecholamine response to head‐up tilt and compared with 22 age‐ and gender‐matched controls. In addition, the patients were examined with a [123I]metaiodobenzylguanidine heart scintigraphy and compared with an external control group.ResultsThe plasma norepinephrine response to head‐up tilt was significantly lower in the patient group than in the control group. Similarly, the heart scintigraphy revealed a lower heart‐to‐mediastinum ratio in the patient group than in the control group. HRV analysis did not reveal significant differences between the groups.ConclusionThe findings of the study showed that the autonomic nervous activity of patients with pRP was altered compared with the activity of healthy individuals. This was observed both during rest and after positional stress, but the findings did not uniformly concur with our initial hypothesis.