bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biomechanical Study of the Stiffness of the Femoral Locking Compression Plate of an External Fixator for Lower Tibial Fractures
Authors: Su Huan , Zhong Siyang , Ma Tianyong , Wu Weidong , Lu Yihong , Wang Dewei 
Published: December 2022

Abstract
Background: A locking compression plate (LCP) of the distal femur is used as an external fixator for lower tibial fractures. However, in clinical practice, the technique lacks a standardized approach and a strong biomechanical basis for its stability.
Methods: In this paper, internal tibial LCP fixator (Group IT-44), external tibial LCP fixator (Group ET-44), external distal femoral LCP fixator (Group EF-44, group EF-33, group EF-22), and conventional external fixator frame (Group CEF-22) were used to fix the unstable fracture models of the lower tibial segment, and anatomical studies were performed to standardize the operation as well as to assess the biomechanical stability and adjustability of the distal femoral LCP external fixator by biomechanical experiments.
Results: It was found that the torsional and flexural stiffness of the group EF-44 and group EF-33 were better than those of the group IT-44 and group ET-44 (p<0.05); the flexural stiffness of the group EF-22 was similar to that of the group IT-44 (p>0.05); and the compressive stiffness of all three EF groups was better than that of the group ET-44 (p<0.05). In addition, the flexural and compressive stiffnesses of the three EF groups decreased with the decrease in the number of screws (p<0.05), while the torsional stiffnesses of the three groups did not differ significantly between the two adjacent groups (p>0.05). In the last point, the group ET-44 had the worst stability (P<0.05).
Conclusions: The study shows that the distal femoral LCP has good biomechanical stability and adjustability, and it is superior to the tibial LCP as an external fixator for distal tibial fractures, as long as the technique is used in a standardized manner according to the anatomical studies in this article.
The Building Emotional Awareness and Mental health (BEAM) program developed with a community partner for mothers of infants: Protocol for a feasibility randomized controlled trial
Authors: Joyce Kayla Marie , Rioux Charlie , MacKinnon Anna L. , Katz Laurence Y , Reynolds Kristin , Kelly Lauren E. , Klassen Terry , Afifi Tracie O. , Mushquash Aislin R. , Clement Fiona M. , Chartier Mariette , Xie Elisabeth Bailin , Penner Kailey , Hunter Sandra , Berard Lindsay , Tomfohr-Madsen Lianne , Roos Leslie E. 
Published: December 2022

Abstract
Background: Drastic increases in the rates of maternal depression and anxiety have been reported since the COVID-19 pandemic began. Most programs aim to improve maternal mental health or parenting skills separately, despite it being more effective to target both concurrently. The Building Emotional Awareness and Mental health (BEAM) program was developed to address this gap. BEAM is a mobile health program aiming to mitigate the impacts of pandemic stress on family well-being. Since many family agencies lack infrastructure and personnel to adequately treat maternal mental health concerns, a partnership will occur with Family Dynamics (a local family agency) to address this unmet need. The study’s objective is to examine the feasibility of the BEAM program when delivered with a community partner to inform a larger randomized controlled trial (RCT).
Methods: A pilot randomized controlled trial will be conducted with mothers who have depression and/or anxiety with a child 6-18 months old living in Manitoba, Canada. Mothers will be randomized to the 10 weeks of the BEAM program or a standard of care. Back-end App data (collected via Google Analytics and Firebase) will be used to examine feasibility, engagement, and accessibility of the BEAM program; cost-effectiveness will also be examined. Implementation elements (e.g., maternal depression [Patient Health Questionnaire-9] and anxiety [Generalized Anxiety Disorder-7]) will be piloted to estimate the effect size and variance for future sample size calculations.
Discussion: In partnership with a local family agency, BEAM holds the potential to promote maternal-child health via a cost-effective and easily accessible program designed to scale. Results will provide insight into the feasibility of the BEAM program and will inform future RCTs of the BEAM program.
Trial Registration: This trial was retrospectively registered with ClinicalTrial.gov (NCT05398107) on May 31st, 2022. https://clinicaltrials.gov/ct2/show/NCT05398107
A holistic and practical framework for evaluating research co-production: Research Quality Plus for Co-Production (RQ+ 4 Co-Pro)
Authors: McLean Robert , Carden Fred , Aiken Alice , Armstrong Rebecca , Bray Judy , Cassidy Christine , Daub Olivia , Ruggiero Erica Di , Fierro Leslie , Gagnon Michelle , Hutchinson Alison , Kislov Roman , Kothari Anita , Kreindler Sara , Mccutcheon Chris , Reszel Jessica , Scarrow Gayle , Graham Ian 
Published: December 2022

Abstract
Background
Co-production is an umbrella term used to describe the process of generating knowledge by bringing together researchers and those who will use research to work in partnership. Multiple benefits of research co-production have been hypothesized, and in some cases documented, in the academic and practice record. However, there are significant gaps in understanding how to evaluate the quality of co-production designs, processes, and results. This gap in knowledge undermines the value of co-production and co-producers.
Methods
Our research tests the relevance and utility of a novel research co-production evaluation framework: Research Quality Plus for Co-Production (RQ + 4 Co-Pro). Following a co-production approach ourselves, members of our team collaborated to develop study objectives, questions, analysis and results sharing strategies. We used a dyadic field-test design to simulate RQ + 4 Co-Pro evaluations amongst 18 independently recruited subject matter experts. We used standardized reporting templates and qualitative interviews to collect data from field-test participants, and thematic analysis and deliberative dialogue to analysis and interpret results.
Results
The field test surfaced unanimous support for the relevance and utility of RQ + 4 Co-Pro. Research participants shared opportunities for fine-tuning language and criteria within the prototype version, but also, for alternative uses and users of RQ + 4 Co-Pro. This data facilitated our deliberative revision and publication herein of a field-tested RQ + 4 Co-Pro Framework and Assessment Instrument.
Conclusion
Evaluation is necessary for understanding and improving co-production, and, for ensuring co-production delivers on its promise of better health, health equity, and general public good. RQ + 4 Co-Pro provides an immediately practical evaluation tool, and we invite co-producers and stewards of co-production – including the funders, publishers, and universities who increasingly claim to encourage socially relevant research – to adapt and experiment with RQ + 4 Co-Pro in their contexts.
Iontophoresis-Driven Microneedles Patch for Active Transdermal Delivery of Vaccine Macromolecules
Authors: Jiang Lelun , Zheng Ying , Ye Rui , Gong Xia , Liu Bin , Xu Yunsheng , Yang Jingbo , Nie Gang , Xie Xi 
Published: December 2022

Abstract
COVID-19 has seriously threatened public health and transdermal vaccination is an effective way to prevent pathogen infection. Microneedles (MN) can damage the stratum corneum for passive diffusion of vaccine macromolecules but the delivery efficiency is low, while iontophoresis can actively promote transdermal delivery but fails to transport vaccine macromolecules due to the barrier of stratum corneum. Herein, we developed a wearable iontophoresis-driven MN patch and its iontophoresis-driven device for active and efficient transdermal vaccine macromolecules delivery. Polyacrylamide/chitosan hydrogels with good biocompatibility, excellent conductivity, high elasticity and large loading capacity were prepared as the key component for vaccine storage and active iontophoresis. The transdermal vaccine delivery strategy of the iontophoresis-driven MN patch is: “press and poke, iontophoresis-driven delivery, and immune response”. We demonstrated that the synergistic effect of MN puncture and iontophoresis could significantly promote the transdermal vaccine delivery efficiency. In vitro experiments showed that the transdermal delivery amount of ovalbumin using iontophoresis-driven MN patch could be controlled by the iontophoresis current. In vivo immunization studies of Balb/c mice demonstrated that transdermal inoculation of ovalbumin using iontophoresis-driven MN patch induced an effective immune response, which was even stronger than that traditional intramuscular injection. Moreover, the iontophoresis-driven MN patch had little biosafety concern. This delivery system is low-cost, user-friendly, and active delivery that shows a great potential in vaccine self-administration at home.
Global Trends in Research on extracorporeal shock wave therapy(ESWT) from 2000 to 2021
Authors: Zhang Xinyu , Ma Yuewen 
Published: December 2022

Abstract
Background: This study intended to analyze the application of extracorporeal shock wave therapy in medicine and to evaluate the quality of related literature.
Methods: All publications were extracted from 2000 to 2021 from the Web of Science Core Collection (WoSCC). The literature characteristics were depicted by VOSviewer (version 1.6.15) and the online bibliometric website (http://bibliometric.com/). The future trends and hotspots were conducted by Bibliographic Item Co-occurrence Matrix Builder (version 2.0) and gCLUTO software.
Results: We analyzed 1774 articles corresponding to the criteria for ESWT publications from 2000 to 2021. Most studies were conducted within the United States and China which besides have the most cooperation. The most published research institutions are Chang Gung University, Kaohsiung Chang Gung Memorial Hospital, and Kaohsiung Medical University. JOURNAL OF ORTHOPAEDIC RESEARCH, AMERICAN JOURNAL OF SPORTS MEDICINE, and JOURNAL OF SURGICAL RESEARCH are the top three most-cited journals. The keyword cluster analysis divides the 30 keywords with the highest frequency into 6 clusters.
Conclusions: With the gradual increase of research on ESWT, we find that ESWT is used more and more extensively, such in musculoskeletal disease, bone delay union, neurological injury, andrology disorders, lymphedema, and so on. In addition, the mechanism is not destructive damage, as initially thought, but a restorative treatment. Furthermore, delayed union, cellulite, burn, and diabetic foot ulcers may be the future direction of scientific study.
Covariates of healthy diet and physical activity self-management one year after Bariatric surgery: A cross sectional study
Authors: Maghsoodlo Maryam , Shakibazadeh Elham , Barzin Maryam , Salimi Yahya , Mokhtari Zeinab , Yaseri Mehdi 
Published: December 2022

Abstract
Background
Healthy diet and physical activity self-management is important in maintaining weight loss and preventing weight regain after bariatric surgery. We aimed at evaluating covariates of healthy diet and physical activity self-management among patients undergone bariatric surgery using Health Action Process Approach (HAPA) model.
Method
In this cross-sectional study, 272 patients with history of bariatric surgery were selected from data registry of Tehran Obesity Treatment Study (TOTS). Data were collected using bariatric surgery self-management standard questionnaire (BSSQ), and items based on HAPA model for healthy diet and physical activity self-management. Data were analyzed using Path analysis and AMOS version 24.
Results
The mean score of self-management was (32 ± 10SD). Coping planning construct (β = 0.22; p < 0.001) and risk perception (β = 0.02; p < 0.01) in dietary self-management and action planning (β = 0.16; p = 0.001) and risk perception (β = 0.001; p = 0.17) in physical activity self-management had the highest and lowest effect powers, respectively. Coping planning (β = 0.22; p < 0.001) and action planning (β = 0.17; p < 0.03) in diet, and action planning (β = 0.16; p = 0.010) in physical activity were significantly related to self-management. Also, task-coping self-efficacy (β = 0.28; and p < 0.001), outcome expectancies (β = 0.37; p < 0.001), risk perception (β = 0.13; p = 0.015) in diet and coping self-efficacy (β = 0.50; p < 0.001), outcome expectancies (β = 0.12; p = 0.021) in physical activity were significantly related to behavioral intention. The values of CFI = 0.939 and RMSEA = 0.052 for diet and CFI = 0.948 and RMSEA = 0.048 for physical activity indicated adequate fit.
Conclusion
HAPA was applicable as a framework for interventions promoting healthy diet and physical activity self-management in patients who undergone bariatric surgery.
Rolling the 2D Sheets of Conjugated Covalent Organic Framework: Transforming into 1D Electronically Conductive Nanotubes
Authors: Li Zhuowei , Tsuneyuki Takahiro , Ghosh Samrat , Nakazato Takumi , Odawara Masahiro , Matsuda Wakana , Nobuoka Masaki , Chen Bin , Paitandi Rajendra , Tsutsui Yusuke , Tanaka Takayuki , Suda Masayuki , Miyake Yoshihiro , Shinokubo Hiroshi , Seki Shu 
Published: December 2022

Abstract
Mimicking the interconvertible carbon allotropes of 2-dimensional (2D) graphene and 1-dimensional (1D) carbon nanotubes, herein we report the in-situ transformation of 2D conjugated covalent organic frameworks (COFs) sheet into 1D nanotubular structures via self-assembly the sheets at solvent interfaces. The facile “roll-the sheets” self-assembly resulted in coaxial nanotubes with uniform cross-sectional diameter, which was realized for aza-pyrene based COF instead of pyrene COF, although both possess very similar chemical structure. Upon replacing the carbon atoms at 2,7-positions of pyrene with nitrogen, contrasting optical and electronic properties was realized reflecting the rolled structure of the conjugated 2D sheets. The nanotubes exhibited semiconducting nature with stable conducting pathways at ambient conditions. The aza centers act as the point for charge carrier doping as evident from the photoconductivity and electrical conductivity results.
New Paradigm of Personal Health Monitoring: Nanomaterial-based In-textile Sensors
Authors: Smith Aaron , Li Rui , Xu Lulu , Tse Zion 
Published: December 2022

Abstract
The use of nanomaterial-based in-textile sensors for personal health monitoring has recently emerged as a new paradigm for healthcare. This approach offers several advantages over traditional monitoring methods, such as increased comfort, convenience, and accuracy. In-textile sensors are integrated into clothing or wearable devices, allowing for continuous and unobtrusive monitoring of a range of physiological parameters, such as heart rate, body temperature, and blood pressure. Nanomaterials such as graphene and carbon nanotubes enable the sensors to be highly sensitive and selective, allowing for the detection of even small changes in the monitored parameters. However, there are also challenges and limitations to the widespread adoption of in-textile sensors for personal health monitoring. One major challenge is the integration of the sensors into wearable devices, as the sensors must be flexible, lightweight, and durable in order to be comfortable and practical for daily use. Additionally, there are concerns about the potential toxicity of some nanomaterials, and more research is needed to assess the safety of these materials for long-term use in personal health monitoring. In this review, we provide an overview of the current state of research on in-textile sensors for personal health monitoring, including the potential benefits and challenges of this technology. This review highlights the potential of in-textile sensors for personal health monitoring, as well as the challenges and limitations of this technology. Further research is needed to address these challenges and fully realize the potential of in-textile sensors for healthcare.
Safety and effectiveness of ByCross Rotational Atherectomy and Aspiration Device: A prospective, multi-center pre-market approval study
Authors: Teßarek Jörg , Kolvenbach Ralf 
Published: December 2022

Abstract

PurposeTo demonstrate safety and effectiveness of the novel ByCross Atherectomy System for percutaneous treatment of TASC A-D de novo infrainguinal arterial >80% stenosis down to the tibioperoneal tract.Materials and Methods41 lesions were treated in this prospective, nonrandomized pre-market approval study across 2 German centers. Mean patient age was 72 years with 62% male. Average lesion length was 125±118 mm (30 to 450mm) with 96.4±6.2% stenosis. The primary performance endpoint was the acute procedural success defined as residual stenosis of ≤ 50% and ≤ 30% after atherectomy and adjunctive treatment. The primary safety endpoint was the major adverse event (MAE) rate through 30 days. Secondary endpoints were DUS measured target lesion restenosis and the ABPI at discharge, 30 and 180 days and any MAE through 6 months.ResultsThe acute procedural success rate was 95.12% with 11/41 (26.82%) lesions being recanalized without wire guidance. Embolic protection was not used. Adjunctive POBA or stenting was used in 40/41 (97.56%) and 12/41 (29.26%), respectively. There were no MAE’s at 30 days. DUS measured mean residual stenosis was 5.7% at discharge and 21.7% at 6 months FU. Mean ABPI was 0.8, 1.0 and 0.8 at baseline, discharge, and 6 months FU respectively.ConclusionsThe ByCross Atherectomy System has shown to be safe and effective for the atherectomy of complex lower-extremity arterial lesions even without guidewire. Trial registration October 17, 2018 ,retrospectively registered. ClinicalTrials.gov Identifier: NCT03724279; https://clinicaltrials.gov/ct2/show/record/NCT03724279
Characterizing the tropical cyclone Seroja using the Indonesian CORS network
Authors: Putri Nabila S.E. , Wijaya Dudy D. , Abdillah Muhammad R. , Tanuwijaya Zamzam A.J. , Wibowo Sidik T. , Kuntjoro Wedyanto 
Published: December 2022

Abstract
In the early April 2021, the tropical cyclone Seroja was formed over the Savu Sea in the southeastern Indonesia. In this study, we utilized the Global Navigation Satellite Systems (GNSS) observations to derive precipitable water vapor (PWV) from several permanent stations in the region to study Seroja. From in situ meteorological observations, we found that surface pressure values dropped by more than 20 hPa during Seroja, relative humidity increased, and temperature was reduced. PWV at two nearest stations showed an upward trend (around 70 mm at its peak) during the formation of the cyclone, then dropped immediately (less than 20 mm). After Seroja, the mean PWV was lower (56 mm before and 39 mm after), whereas the standard deviation was higher (5-6 mm before and 9 mm after). We also compared hourly PWV with precipitation from GSMaP. Before Seroja, some precipitation events occurred, followed by heavy rains that lasted for several days when the cyclone was passing. After Seroja had passed, both PWV and precipitation dropped significantly. However, while PWV values after Seroja was fluctuating, no rain occurred. We then investigated the water vapor budget to understand the change of PWV over time. We found that precipitation and the divergence of moisture flux played an important role in the change of PWV over time. Heavy precipitation during Seroja resulted in a drop in PWV, although the negative divergence provided a bit of offset. After Seroja had passed, no precipitation occurred and the change of PWV could be attributed mainly to the moisture divergence. The lagged correlation between PWV and precipitation was determined using moving average over the timeseries. The highest correlation was found 1-2 days before the event with moving average periods of 7 and 10 days.
Ultra-scaled Phototransistors based on Monolayer MoS2
Authors: Schranghamer Thomas , Das Saptarshi 
Published: December 2022

Abstract

For decades, the fundamental diffraction limit of light has stymied the dimension scaling for optoelectronic devices, which remain largely stuck at the micrometer scale or larger. However, recent studies have shown that nanoantennas and plasmonic devices capable of capturing/directing electromagnetic waves are one avenue of artificially focusing incident light into sub-wavelength active areas, thus enabling applications such as photodetection and communication in defiance of the diffraction limit. Despite these advancements, the ultimate scaling limits of photodetector active areas have remained largely untested. In this work, we present a two-dimensional (2D) monolayer molybdenum disulfide (MoS2) photodetector that is able to reach responsivities and detectivities in excess of 108 A/W and 1012 Jones, respectively, and display a high dynamic range while possessing an active area of only 0.0065 μm2. Together, the nano-scale active area and ultra-thin-body nature of the sensing material correspond to an active volume of ~4.23 × 10-6 μm3, approximately 3× smaller than the current smallest photodetector reported in the literature. These results indicate that continued scaling of photodetectors beyond the diffraction limit has enormous potential so long as methods of focusing incident light continued to be developed concurrently.
Phase angle is related to physical function and quality of life in preoperative patients with lumbar spinal stenosis
Authors: Otsubo Ryota , Hashida Ryuki , Murotani Kenta , Iwanaga Sohei , Hirota Keisuke , Koya Syunji , Tsukada Yuya , Ogata Yuta , Yokosuka Kimiaki , Yoshida Tatsuhiro , Nakae Ichiro , Fudo Takuma , Morito Shinji , Shimazaki Takahiro , Yamada Kei , Sato Kimiaki , Matsuse Hiroo , Shiba Naoto , Hiraoka Koji 
Published: December 2022

Abstract
Lumbar spinal stenosis (LSS) can interfere with daily life and quality of life (QOL). Evaluating physical function and QOL and helping them to improve is the focus of rehabilitation. Phase angle (PhA) assessment is widely used to measure body composition and is considered an indicator of physical function and QOL. This study investigated the relationship between PhA and physical function, physical activity, and QOL in patients with LSS. PhA, handgrip strength, walking speed, Timed Up and Go test (TUG), Life Space Assessment (LSA), Prognostic Nutritional Index (PNI), Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ), and EQ-5D were assessed and statistically analyzed. The study included 104 patients with LSS. Multiple regression analysis of PhA adjusted for age, sex, and body mass index (Model 1) and for Model 1 + PNI (Model 2) showed significant correlations (P < 0.05) with handgrip strength, walking speed, TUG, and LSA. Regarding QOL, PhA showed a significant correlation (P < 0.05) with lumbar function in JOABPEQ and a significant trend (P < 0.1) in EQ-5D in both models. PhA was associated with physical function and QOL in patients with LSS and may be a new clinical indicator in this population.