bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cellulase activity of bacteria isolated from water of mangrove ecosystem in Aceh Province
Authors: Dewiyanti Irma , Darmawi Darmawi , Muchlisin Zainal Abidin , Helmi Teuku Zahrial , Arisa Iko Imelda , Defira Cut Nanda , Fitriyani Fitriyani , Yura Sawva 
Published: January 2022

Cellulolytic bacteria that produce cellulase enzymes play an essential role in degrading cellulose in their habitat. The presence of cellulolytic bacteria strongly supports the fertility and productivity in mangrove waters. The objectives of the study are to analyze the activity of cellulase enzyme qualitatively through the cellulolytic index and quantitatively through the activity and specific activity of the cellulase enzyme from bacteria isolated from the water of mangrove ecosystems in Aceh Province. The qualitative experiment of enzyme activity was carried out at the Microbiology laboratory SKIPM Aceh, and a quantitative experiment of enzyme activity was conducted at the Microbiology Laboratory, Biology Department, IPB. Isolation of cellulolytic bacteria isolated from mangrove water used Carboxy Methyl Cellulose (1% CMC) selective media and carried out by spread plate method. The ability of bacteria to produce cellulase was tested qualitatively using the spot technique, this test was carried out using 1% Congo Red. Furthermore, the quantitative testing of cellulase enzymes activity adopted the DNS spectrophotometric method. The specific activity of the cellulase enzyme can be determined by using the Lowry method. There were 21 isolates that had a clear zone and had the ability to produce cellulase enzymes from 49 isolates that were successfully purified. The highest cellulolytic index (CI) produced using BAM421 isolate with the value of 5.50 was included in the high category, followed by BAM326 and BAM132 isolates, with values of 1.55 and 1.05 were categorized into the medium category. The other isolates were in the low cellulolytic index category. The isolate with the highest CI value was further tested using the quantitative enzyme activity test. The highest cellulase enzyme activity of BAM421 occurred at 24hr (0.0029 U/ml). The highest specific cellulase activity of BAM421 was at 24hr with the value of 0.210 U/mg. The result concluded that the qualitative test showed CI values can be categorized into low, medium, and high. Moreover, the value of the quantitative assay described that the cellulase enzyme and the specific enzyme activities of the bacteria were low in the study area.Keywords:Cellulolytic indexQuantitative testMangrove watersCellulase enzymeMicroorganismTRANSLATE with x EnglishArabicHebrewPolishBulgarianHindiPortugueseCatalanHmong DawRomanianChinese SimplifiedHungarianRussianChinese TraditionalIndonesianSlovakCzechItalianSlovenianDanishJapaneseSpanishDutchKlingonSwedishEnglishKoreanThaiEstonianLatvianTurkishFinnishLithuanianUkrainianFrenchMalayUrduGermanMalteseVietnameseGreekNorwegianWelshHaitian CreolePersian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster PortalBack//
Learning-based compensation of spatially varying aberrations for holographic display [Invited]
Authors: Yoo Dongheon , Nam Seung-Woo , Jo Youngjin , Moon Seokil , Lee Chang-Kun , Lee Byoungho 
Published: January 2022

We propose a hologram generation technique to compensate for spatially varying aberrations of holographic displays through machine learning. The image quality of the holographic display is severely degraded when there exist optical aberrations due to misalignment of optical elements or off-axis projection. One of the main advantages of holographic display is that aberrations can be compensated for without additional optical elements. Conventionally, computer-generated holograms for compensation are synthesized through a point-wise integration method, which requires large computational loads. Here, we propose to replace the integration with a combination of fast-Fourier-transform-based convolutions and forward computation of a deep neural network. The point-wise integration method took approximately 95.14 s to generate a hologram of

1024
×
1024

p
i
x
e
l
s

, while the proposed method took about 0.13 s, which corresponds to

×
732

computation speed improvement. Furthermore, the aberration compensation by the proposed method is verified through experiments.
Characteristics of a rectangular channel sensor based on evanescent field enhanced photonic crystal fiber
Authors: Shen Tao , Liang Han , Liu Xin , Feng Yue , Xu Tao , Liu Chi , Han Wei 
Published: January 2022

A miniaturized, rectangular-channel photonic crystal fiber (RC-PCF) high-sensitivity sensing scheme is proposed for high-refractive-index liquid analysis. The designed PCF is polished and features an open rectangular channel in the upper-middle part of the fiber cross-section, which facilitates the efficient flow of the sample liquid. The design utilizes the merit of photonic crystal array and the operability of external sensing. Gold is chosen as the plasma material because of its chemical stability and biocompatibility in a liquid environment. To obtain high sensitivity, the effect of the sample liquid height in the channel on the sensing performance is investigated. Numerical results show that the maximum wavelength sensitivity and amplitude sensitivity of the sensor is 28,000 nm/RIU (refractive index unit) and

−

1266.5

R
I

U

−
1

with a liquid analyte height of 100% of the channel height. The maximum wavelength sensitivity increases from 28,000 to 42,000 nm/RIU when the gold film thickness decreases from 30 nm to 20 nm. Due to the sensor’s simple structure and high sensitivity, it will have potential applications in the detection of high-refractive-index samples in biology, medicine, and chemistry.
Enlarged range of measurement method with strong noise resistance for dual-wavelength digital holography: erratum
Authors: Li Tuo , Tao Ye , Dong Jun , Zhang Qian , Wang Shuai , Shi Yishi 
Published: January 2022

We present an erratum to our Letter [Opt. Lett.
46, 4694 (2021)10.1364/OL.432135]. This
erratum corrects an unintended error in the labels of
Figs. 5(h)–5(j). The corrections have no influence on the
results and conclusions of the original Letter.
Broadly tunable lens-coupled nonlinear quantum cascade lasers in the sub-THz to THz frequency range
Authors: Fujita Kazuue , Hayashi Shohei , Ito Akio , Dougakiuchi Tatsuo , Hitaka Masahiro , Nakanishi Atsushi 
Published: January 2022

Room-temperature terahertz (THz) quantum cascade laser sources with intracavity difference-frequency nonlinear mixing are electrically pumped monolithic semiconductor laser sources operating in the 0.6–6 THz spectral range. We report widely tunable, low-frequency THz quantum cascade laser sources using a lens-coupled Cherenkov waveguide scheme. Based on a watt-class high-power,

λ
∼
13.7

μm

quantum cascade laser, the monolithic THz source is strongly coupled with a high-resistivity silicon lens, which causes a major increase in the THz coupling efficiency and demonstrates significant performance improvements. A room-temperature 1.5 THz device produces a 0.2 mW peak output power with a high-quality beam pattern. Improved THz outcoupling efficiency using the lens-coupled scheme enabled the demonstration of a high-performance external-cavity semiconductor THz source that is tunable from 420 GHz to 2 THz. The external-cavity, lens-coupled device configuration can technically be assembled into a butterfly-style package for a thumb-sized, widely frequency tunable THz semiconductor source.
Gestão do cuidado e matriciamento na atenção primária à saúde: um relato de experiência
Authors: Figueiredo Minéia da Costa , Paula Fabiana Lopes de 
Published: January 2022

Este artigo irá abordar a vivência em uma unidade de Estratégia Saúde da Família (ESF) no município de Canto do Buriti-PI sobre os aspectos relacionados ao processo de matriciamento e a gestão do cuidado. A descrição será feita a partir da análise da gestão do cuidado e articulações com o Núcleo de Apoio à Saúde da Família (NASF) e suas ações de apoio matricial desenvolvidas na unidade. O NASF tem fundamental importância na resolução de casos mais complexos e na efetivação de cuidado integral, bem como para a assistência humanizada aos usuários na Atenção Primária à Saúde. O relato traz como contribuição a análise do processo de trabalho entre eSF e NASF, com uma visão que traz subsídios para a reflexão; tendo a intenção de cooperar para o aperfeiçoamento, progresso das ações na APS e a concretização das políticas públicas.
Palavras-chave: Atenção Primária à Saúde; Estratégia Saúde da Família; Equipe de Assistência ao Paciente; Integralidade em Saúde; Sistema Único de Saúde.

Abstract
This article will address the experience in a Family Health Strategy (ESF) unit in the city of Canto do Buriti-PI on aspects related to the matrix support process and care management. The description will be made from the analysis of care management and articulations with the Family Health Support Center (NASF) and its matrix support actions developed in the unit. The NASF is of fundamental importance in solving more complex cases and in providing comprehensive care, as well as in providing humanized assistance to users in Primary Health Care. The report contributes to the analysis of the work process between eSF and NASF, with a a vision that supports reflection; with the intention of cooperating for the improvement, progress of actions in the PHC and the implementation of public policies.
Keywords: Primary Health Care; Family Health Strategy; Patient Care Team; Integrality in Health; Unified Health System.
Condução de manejo de comportamento associadas a terapias integrativas em pacientes odontopediátricos: Revisão de literatura / Conducting association treatment associated with integrative therapies in pediatric dental patients: Literature review
Authors: Souto Thainá Cardoso , Souza Isabela Nunes , Carvalho Milena Tavares de 
Published: January 2022

O objetivo deste artigo foi dispor aos profissionais conhecimento e embasamento sobre o uso de terapias integrativas em controle de comportamento em pacientes odontopediátricos. Trata-se de uma revisão de literatura de cunho narrativo e caráter exploratório que será fundamentado na coleta de artigos científicos nas principais bases de dados: Scielo, Lilacs, PubMed e Google Acadêmico. Buscou-se contribuir cientificamente com o conhecimento a fim de empregar corretamente a condução de manejo com terapias integrativas mais adequadas a cada situação no atendimento clínico odontopediátrico. Conclui-se que o conhecimento técnico e científico do manejo do comportamento infantil e das terapias integrativas no atendimento odontológico infantil é fundamental em busca de desenvolvimento físico e emocional de modo satisfatório. ---The aim of this article was to provide professionals with knowledge and foundation on the use of integrative therapies in behavior control in pediatric dental patients. This is a literature review of a narrative and exploratory nature that will be based on the collection of scientific articles in the main databases: Scielo, Lilacs, PubMed and Academic Google. We sought to contribute scientifically with knowledge in order to correctly employ the management of the most appropriate integrative therapies for each situation in pediatric clinical care. It is concluded that technical and scientific knowledge of the management of child behavior and integrative therapies in child dental care is essential in the search for satisfactory physical and emotional development.
Utilization of Dietitians in the Management of Irritable Bowel Syndrome by Members of the American College of Gastroenterology
Authors: Scarlata Kate , Eswaran Shanti , Baker Jason R. , Chey William D. 
Published: January 2022

INTRODUCTION:
The aim of this study was to identify benefits and barriers to using a gastroenterology (GI) dietitian for irritable bowel syndrome (IBS) care.

METHODS:
A 25-question survey was electronically distributed to the members of the American College of Gastroenterology. Information pertaining to demographics, barriers, and values to using a GI dietitian for IBS patient care was collected.

RESULTS:
Two hundred seventy-nine survey responses were collected. Although 56% of the GI providers feel they are trained to provide nutrition education, almost half (46%) sometimes, rarely, or never provided information to aid menu planning, label reading, or grocery shopping, and 77% spent ≤10 minutes for nutrition counseling. Of those with access to a local dietitian, 91% strongly agreed or agreed that having access to a GI dietitian would help them manage their IBS patient care more effectively, but 42% lack access to a local GI dietitian.

DISCUSSION:
Our survey identified gaps in nutrition-based interventions for IBS care.
Long-term β-cells autoimmune destruction markers persistence and residual C-peptide secretion in type 1 diabetes mellitus
Authors: Ragimov M. R. , Derevyanko O. S. , Malysheva N. M. , Zuraeva Z. T. , Nikankina L. V. , Nikonova T. V. 
Published: January 2022

Backgraund: It believed that autoimmune process maintained only during the first 5 years of diabetes mellitus type 1 (T1D). Recently scientists discovered the high levels of islet autoantibodies (Ab) in long-standing T1D and some of these patients had residual insulin secretion, determined by the level of C-peptide. According to various sources, the prevalence of such observations ranges from 12 to 48%.Aims: The aim of our study was to assess the duration of autoimmune β-cells destruction markers persistence and residual fasting C-peptide secretion in the long-standing T1D, as well as to determine the possible causes and patterns of these processes.Materials and methods: In the study included 237 patients (91 men, 146 women) with T1D. Patients divided in 4 groups, according to disease duration: а — up to 1 year, n=69 (29%); b — 1–5 years, 52 (22%); c — 5–10 years, 57 (24%); d — more than 10 years, 59 (25%). Ab to glutamic acid decarboxylase (GADA), tyrosine phosphatase-like IA-2 (IA2) and zinc T8 (ZnT8A) were detected by Enzyme Immunoassay. Also detected C-peptide levels and retrospectively HbA1с.Results: Antibodies to antigens of β-cell components were detected in 26 (37%) patients in group A, in 17 patients (33%) in group B, in 15 (29%) in group C and in 14 (23%) — G.In the control group (n = 19), an increased level of antibodies was not revealed. Fasting C-peptide levels were as follows: in group «A» — 0.86 ng / ml [0.53; 1.4], «B» — 0.65 ng / ml [0.27; 0.98], « B «- 0.19 ng / ml [0.17; 0.33],» D «- 0.01 ng / ml [0.01; 0.01]. However, in 13 (22%) patients in group D, fasting C-peptide levels were more than 0.09 ng / ml.Conclusion: The data obtained indicate a long-term persistence of markers of the autoimmune process in patients with T1DM. In groups with a long (more than 5 years) course of T1DM, levels of fasting C-peptide more than 30 pmol/L (0.09 ng / ml or 0.03 nmol / L) were noted in 39 (33.6%) cases.
Physical Activity Profile and Risk of Type 2 Diabetes Mellitus in Udupi (India) Population
Authors: Ladha N. , Maiya A. , Prabhu N. , Kumar A.S. , G S. , Kalkura P. 
Published: January 2022

Background: Throught the world, More than 75% of adults with type 2 diabetes mellitus (T2DM) live in low and middle-income countries. Amongst which 69.2 million of these adults live in India. Its been shown that, as level of physical activity increases, risk of developing T2DM decreases by 15-60%. Many studies are conducted to find the risk of development of T2DM in the coastal areas of Karnataka. However, the screening of people living in Udupi was not carried out.Aim: To find out the risk for the development of T2DM using IDRS and physical activity levels in Udupi population.Material and Methods: In the current study, we included participants who were asymptomatic and undiagnosed to be having T2DM. The participants age ranged between 30–65 yrs. Participants with the history of any neurological conditions and women who were pregnant at the time of screening were excluded. We recorded random blood glucose levels of the participants following which the risk score was obtained using the Indian Diabetes Risk Score (IDRS) and the participants were classified as high risk (score ≥60), moderate risk score (30–50) and low risk (score <30). The level of physical ­activity was measured using Global Physical Activity Questionnaire.Results: The study included 23,960 participants from Udupi district, Karnataka. Based on IDRS risk stratification, 1.5%, 17.9%, 27.5% of the participants with the age ange of 30–35 yrs, 36–50 yrs and more than 50 yrs respectively had higher risk of developing T2DM. According to GPAQ score 14% of the participants were following sedentary lifestyle, 27.6% of the were minimally active, 53.7% were very active, and 4.6% were highly active.Conclusion: From the current study we conclude that 46.9% of participants had a higher risk of developing T2DM in future who are living in Udupi district.
Clinical, hormonal and molecular-genetic characteristics of monogenic diabetes mellitus associated with the mutations in the <i>INS</i> gene
Authors: Tikhonovich Yu. V. , Petryaykina E. E. , Timofeev A. V. , Zubkova N. A. , Kolodkina A. A. , Sorkina E. L. , Vasiliev E. V. , Petrov V. M. , Andrianova E. A. , Zilberman L. I. , Svetlova G. N. , Кalinin A. L. , Rubtsov P. M. , Кiselev S. L. , Panova A. V. , Shreder E. V. , Krasnova T. S. , Kulieva B. P. , Gariaeva I. V. , Rybkina I. G. , Malievskiy O. A. , Tyulpakov A. N. 
Published: January 2022

Background:Currently more than 50 mutations of the INS gene are known to affect the various stages of insulin biosynthesis in the beta cells of the pancreas. However only individual cases of diabetes mellitus (DM) associated with heterozygous mutations in the coding region of the INS gene were reported in Russian Federation. We report a group of patients with a clinical manifestation of DM caused by mutations in both coding and non-coding regions of the INS gene. The patients with a mutation in the intron of the INS gene are reported for the first time in Russian FederationMaterials and methods: 60 patients with an isolated course of neonatal DM (NDM), 52 patients with a manifestation of DM at the age of 7–12 months and the absence of the main autoimmune markers of type 1 DM, 650 patients with the MODY phenotype were included in the study. NGS technology was used for molecular genetic research. Author’s panel of primers (Custom DNA Panel) was used for multiplex PCR and sequencing using Ion Ampliseq™ technology. The author’s panel “­Diabetes Mellitus” included 28 genes (13 candidate genes of MODY and other genes associated with DM).Results:13 heterozygous mutations were identified in 16 probands and 9 relatives. The majority of mutations were detected in patients with PNDM (18.75%) and in patients with an onset of DM at the age of 7–12 months (9.6%). Mutations in the INS gene were detected in 2 patients (0.3%) in the group with the MODY phenotype. Mutations in the INS gene were not detected in patients with transient NDM (TNDM). Analysis of clinical data in patients with PND and onset of diabetes at the age of 7–12 months did not show significant differences in the course of the disease. The clinical characteristics of the cases of MODY10 and diabetes caused by a mutation in the intron of the INS gene are reported in details.Conclusion:The role of INS gene mutations in NDM, MODY, and DM with an onset at the age of 7–12 months was analyzed in a large group of patients. The clinical characteristics of DM due to a mutation in the intron of the INS gene are reported for the first time in the Russian Federation.
Quality of ejaculate of male patients with type 2 diabetes mellitus (DM), vaccinated with GamCovidVac (Sputnik V)
Authors: Esaulenko D. I. , Rozhivanov R. R. , Shishkina V. V. 
Published: January 2022

Background: New coronavirus infection (Covid-19) in patients with diabetes type 2 mellitus (DM) often has severe clinical course and manifestation. This comorbidity is a reasonable indication for vaccination. Male patients are often concerned about the vaccination impact on their fertility, so the current research of this issue seems to be essential and relevant.Aims: To evaluate the quality of ejaculate in type 2 diabetes mellitus (DM) patients, vaccinated by GamCovidVac (Sputnik V).Materials and Methods: The pilot observational prospective study included 30 males with type 2 diabetes mellitus (DM). The study continued from February 2021 till June 2021. The research design involved medical history analysis, glycated hemoglobin (HbA1c) tests, total testosterone level in blood measurement, semen analysis (sperm count test). Group comparison was performed by Wilcoxon Signed Ranks Test. The differences were considered statistically significant at p<0.05.Results: After vaccination 19 patients (63%) demonstrated a temperature rise which lasted for 2 days; 26 patients (87%) complained of tenderness in the injections site which lasted up to 5 days. Though a few patients reported general somatic side effects after the vaccination, there have been no statistically significant deviations in sperm count, viability, function and morphology. The levels of glycated hemoglobin and total testosterone remained unchanged.Conclusion: The study revealed no negative impact of GamCovidVac on ejaculate quality, total testosterone level and compensation of carbohydrate metabolism.
Remote monitoring of adolescents with type 1 diabetes mellitus using a mobile application
Authors: Laptev D. N. , Eremina I. A. , Karpushkina A. V. , Petryaykina E. E. , Bezlepkina O. B. , Peterkova V. A. 
Published: January 2022

Background: The prevalence of type 1 diabetes mellitus (T1DM) in childhood is increasing every year. Adolescence is the most challenging age for achieving optimal metabolic control of T1DM. Telemedicine has already been shown to be ­effective in children with the condition, but there are not enough studies in adolescents. The use of mobile apps may be associated with better glycemic control in patients with type 1 diabetes.Aims: To assess the effectiveness and safety of a model of medical care for adolescents with type 1 diabetes using remote counseling and a mobile application.Materials and methods: Were included adolescents aged ≥14 and 18 years with a T1DM duration> 3 months, a glycated hemoglobin level (HbA1c)> 7%. The duration of the study was 26 weeks. There were 3 face-to-face and at least 4 remote visits using a mobile application. All patients underwent standard examination and anthropometry, study of HbA1c, registration and analysis of indicators, assessment and correction of the treatment. The quality of life of adolescents was assessed at baseline and at the end of the study. Adolescents and physicians were interviewed about program evaluation.Results: 56 patients were included, 7 adolescents withdrew. HbA1c significantly decreased by the 12th week of the study (–0.3%; p = 0.005), by the end of the study the change in HbA1c was –0.5% (p <0.001). There was an increase in the percentage of glucose measurements in the target range (+5.3 pp; p = 0.016) and a decrease in blood glucose variability (-3.1 pp; p = 0.015). There was a significant improvement in both the total assessment of the quality of life by patients (+2.9 points; p = 0.008) and individual components of its indicators: attitude to diabetes (+3.0 points; p = 0.049), attitude to treatment (+4.6 points; p = 0.010) and communication with others (+4.5 points; p = 0.015). The majority of doctors and patients assessed their participation in the study positively. The incidence of adverse events did not change significantly during the study from baseline.Conclusion: Remote counseling using a mobile app is a safe and effective approach for adolescents with T1DM in terms of glycemic control and quality of life, and provides convenience and speed of interaction.