bluuebunny/crossref_metadata_2025_split huggingface dataset:
Living a frozen life: a qualitative study on asylum seekers’ experiences and care practices at accommodation centers in Sweden
Authors: van Eggermont Arwidson Charlotta , Holmgren Jessica , Gottberg Kristina , Tinghög Petter , Eriksson Henrik 
Published: September 2022

Abstract
Background
Forced migrants fleeing conflict and violence face a high risk of mental health problems due to experiences before displacement, perilous journeys, and conditions in the new host societies. Asylum seekers seem to be in particularly vulnerable situations, indicated by higher prevalence rates of mental health problems compared to resettled refugees. Asylum seekers’ mental health is highly influenced by the conditions they face in host countries while awaiting a decision on their case. In Sweden, 40% of asylum seekers reside in state-provided accommodation centers during the asylum process. Collective accommodation centers for asylum seekers have been said to impose restrictive social conditions and to be associated with poorer mental health outcomes than other housing forms (e.g., self-organized housing). However, there seems to be a scarcity of qualitative studies exploring the experiences of asylum seekers in different contexts. The aim of this study was therefore to explore the experiences of asylum seekers and how they manage their mental wellbeing while living at accommodation centers in Sweden.

Methods
Fourteen semi-structured interviews with asylum seekers were conducted at two accommodation centers in Sweden. Participants were recruited using purposeful sampling and represented a diverse group of asylum seekers regarding age, background, and gender. The data was analyzed using content analysis.

Results
Three overarching categories were identified; 1) Frozen life, 2) Constant worrying and “overthinking”, and 3) Distractions and peer support. Participants experienced a state of being that could be characterized as a frozen life, which was associated with intense feelings of psychological distress, mostly described as manifesting itself in consuming patterns of ruminative thoughts, for instance overthinking and constant worrying. However, despite high levels of distress, participants demonstrated agency in managing negative mental health outcomes through self-care practices, peer support, and the development of care practices in caring for others in need.

Conclusion
This study offers new insights into the everyday challenges that asylum seekers at accommodation centers face. Furthermore, it offers valuable observations of how asylum seekers at accommodation centers cope through self-care practices, peer support, and care practices in caring for peers in need. In order to enable sustainable and empowering support, mental health and psychosocial support services must identify and address both challenges and strengths, be grounded in the lived reality of asylum seekers, and build on existing resources. Moreover, further policy work needs to be done to enable faster asylum processes.
The agreement and repeatability of measurements of ankle joint dorsiflexion and poplietal angle in healthy adolescents
Authors: Pietrzak Krzysztof , Miechowicz Izabela , Nowocień Krzysztof , Kraszewski Bartosz , Rzymski Piotr 
Published: September 2022

AbstractBackgroundThe intra‐rater repeatability and inter‐rater agreement of orthopaedics measurements are important for estimating injury risk and appropriate treatment. In clinical practice, it is often unavoidable to trust the measurements of other health professionals.MethodsThis study tested the agreement and repeatability of measurements of the dorsiflexion of the foot, dorsiflexion with 90‐degrees knee flexion, and popliteal angle test in healthy adolescents performed twice by three raters differing in clinical experience. Three raters, i.e., an orthopaedics specialist (16 years of experience), a resident medical doctor in orthopaedics (4 years of experience), and a physiotherapy student (1 year of experience) measured the ankle joint dorsiflexion and the popliteal angle in 142 healthy adolescent subjects.ResultsThe student outperformed more experienced raters by displaying good repeatability for all the evaluated parameters. The orthopaedics specialist failed to replicate the measurements of the left ankle joint passive dorsiflexion and the left popliteal angle. The medical resident in orthopaedics displayed a lack of repeatability in evaluating the right ankle joint dorsiflexion with the knee joint bent. Kendall's W value for all parameters ranged 0.66–0.78, indicating a good inter‐rater agreement.ConclusionsThe study highlights that measurements of the ankle joint dorsiflexion and popliteal angle test by different health professionals can generally be trusted. It indicates that novice health professionals could potentially evaluate such parameters in healthy subjects without a quality loss.
An optimized mouse model of Staphylococcus aureus infected diabetic ulcers
Authors: MENDES Ana Isabel , PEIXOTO Maria João , MARQUES Alexandra Pinto , PEDROSA Jorge , FRAGA Alexandra Gabriel 
Published: September 2022

Abstract
Objective
Diabetic foot infection (DFI) represents a major healthcare burden, for which treatment is challenging owing to the pathophysiological alterations intrinsic to diabetes and the alarming increase of antimicrobial resistance. Novel therapies targeting DFI are therefore a pressing research need for which proper models of disease are required.

Results
Here, we present an optimized diabetic mouse model of methicillin-resistant Staphylococcus aureus (MRSA)-infected wounds, that resemble key features of DFI, such as pathogen invasion through wound bed and surrounding tissue, necrosis, persistent inflammation and impaired wound healing. Thus, in a time-efficient manner and using simple techniques, this model represents a suitable approach for studying emerging therapies targeting DFI caused by MRSA.
SARS CoV- 2 vaccination induces antibodies against cardiolipin
Authors: Krashias George , Pafiti Anna , Deeba Elie , Christodoulou Christina , Pantzaris Marios , Lambrianides Anastasia 
Published: September 2022

Abstract
Objective
Cases of thrombosis have been reported after administration of SARS-CoV-2 vaccines, with controversial results relating to Oxford-AstraZeneca’s ChAdOx1-S. Despite such cases being rare, they still raised concerns for their involvement in coagulopathies. Anti-cardiolipin (aCL) IgG antibodies have been linked to venous and arterial thrombosis. The aim was to evaluate the concentration of aCL IgG antibodies in vaccinated and COVID-19 positive individuals using indirect ELISA and commercial sourced calibrators.

Results
The concentration of aCL IgG antibodies was measured in the serum of COVID-19 positive (n = 37), ChAdOx1-S vaccinated (n = 37) and BioNTech Pfizer BNT162b2 vaccinated (n = 42) individuals. Samples from COVID-19 negative, unvaccinated individuals (n = 41) served as controls. The highest percentage of positivity was in the COVID-19 positive group (18.9%). Concerning vaccination, BNT162b2 had the highest percentage of positivity (11.9%) (p = 0.0037). Additionally, aCL concentrations were evaluated at different time points in both vaccinated groups (before, 3 weeks after and 3 months after the second dose). A significant difference in the levels of aCL IgG antibodies over time (p = 0.0391) was observed only in ChAdOx1-S individuals. Our study concluded that levels of aCL, after vaccination with either of the vaccines or following SARS-CoV-2 infection, were not clinically pathogenic for the risk of thrombosis.
Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation
Authors: Klafki Hans-W. , Vogelgsang Jonathan , Manuilova Ekaterina , Bauer Chris , Jethwa Alexander , Esselmann Hermann , Jahn-Brodmann Anke , Osterloh Dirk , Lachmann Ingolf , Breitling Benedict , Rauter Carolin , Hansen Niels , Bouter Caroline , Palme Stefan , Schuchhardt Johannes , Wiltfang Jens 
Published: September 2022

Abstract
Background
Measurements of the amyloid-β (Aβ) 42/40 ratio in blood plasma may support the early diagnosis of Alzheimer’s disease and aid in the selection of suitable participants in clinical trials. Here, we compared the diagnostic performance of fully automated prototype plasma Aβ42/40 assays with and without pre-analytical sample workup by immunoprecipitation.

Methods
A pre-selected clinical sample comprising 42 subjects with normal and 38 subjects with low cerebrospinal fluid (CSF) Aβ42/40 ratios was studied. The plasma Aβ42/40 ratios were determined with fully automated prototype Elecsys® immunoassays (Roche Diagnostics GmbH, Penzberg, Germany) by direct measurements in EDTA plasma or after pre-analytical Aβ immunoprecipitation. The diagnostic performance for the detection of abnormal CSF Aβ42/40 was analyzed by receiver operating characteristic (ROC) analysis. In an additional post hoc analysis, a biomarker-supported clinical diagnosis was used as a second endpoint.

Results
Pre-analytical immunoprecipitation resulted in a significant increase in the area under the ROC curve (AUC) from 0.73 to 0.88 (p = 0.01547) for identifying subjects with abnormal CSF Aβ42/40. A similar improvement in the diagnostic performance by pre-analytical immunoprecipitation was also observed when a biomarker-supported clinical diagnosis was used as a second endpoint (AUC increase from 0.77 to 0.92, p = 0.01576).

Conclusions
Our preliminary observations indicate that pre-analytical Aβ immunoprecipitation can improve the diagnostic performance of plasma Aβ assays for detecting brain amyloid pathology. The findings may aid in the further development of blood-based immunoassays for Alzheimer’s disease ultimately suitable for screening and routine use.
Generalized Lommel–Wright function and its geometric properties
Authors: Zayed Hanaa M. , Mehrez Khaled 
Published: September 2022

AbstractThe normalization of the combination of generalized Lommel–Wright function$\mathfrak{J}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z)$Jκ1,κ2κ3,m(z)(m∈N,$\kappa _{3}>0$κ3>0andκ1,κ2∈C) defined by$\mathfrak{J}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z):=\Gamma ^{m}( \kappa _{1}+1)\Gamma (\kappa _{1}+\kappa _{2}+1)2^{2\kappa _{1}+ \kappa _{2}}z^{1-(\kappa _{2}/2)-\kappa _{1}}\mathcal{J}_{\kappa _{1},\kappa _{2}}^{ \kappa _{3},m}(\sqrt{z})$Jκ1,κ2κ3,m(z):=Γm(κ1+1)Γ(κ1+κ2+1)22κ1+κ2z1−(κ2/2)−κ1Jκ1,κ2κ3,m(z), where$\mathcal{J}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z):=(1-2\kappa _{1}-\kappa _{2})J_{\kappa _{1},\kappa _{2}}^{ \kappa _{3},m}(z)+z ( J_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z) ) ^{\prime}$Jκ1,κ2κ3,m(z):=(1−2κ1−κ2)Jκ1,κ2κ3,m(z)+z(Jκ1,κ2κ3,m(z))′and$$ J_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z)= \biggl( \frac{z}{2} \biggr) ^{2\kappa _{1}+\kappa _{2}}\sum_{n=0}^{\infty} \frac{(-1)^{n}}{\Gamma ^{m} ( n+\kappa _{1}+1 ) \Gamma ( n\kappa _{3}+\kappa _{1}+\kappa _{2}+1 ) } \biggl( \frac{z}{2} \biggr) ^{2n}, $$Jκ1,κ2κ3,m(z)=(z2)2κ1+κ2∑n=0∞(−1)nΓm(n+κ1+1)Γ(nκ3+κ1+κ2+1)(z2)2n,was previously introduced and some of its geometric properties have been considered. In this paper, we report conditions for$\mathfrak{J}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z)$Jκ1,κ2κ3,m(z)to be starlike and convex of orderα,$0\leq \alpha <1$0≤α<1, inside the open unit disk using some technical manipulations of the gamma and digamma functions, as well as inequality for the digamma function that has been proved (Guo and Qi in Proc. Am. Math. Soc. 141(3):1007–1015, 2013). In addition, a method presented by Lorch (J. Approx. Theory 40(2):115–120 1984) and further developed by Laforgia (Math. Compet. 42(166):597–600 1984) is applied to establish firstly sharp inequalities for the shifted factorial that will be used to obtain the order of starlikeness and convexity. We compare then the obtained orders of starlikeness and convexity with some important consequences in the literature as well as the results proposed by all techniques to demonstrate the accuracy of our approach. Ultimately, a lemma by (Fejér in Acta Litt. Sci. 8:89–115 1936) is used to prove that the modified form of the function$\mathfrak{J}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z)$Jκ1,κ2κ3,m(z)defined by$\mathcal{I}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z)=\mathfrak{J}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z)\ast z/(1+z) \ $Iκ1,κ2κ3,m(z)=Jκ1,κ2κ3,m(z)∗z/(1+z)is in the class of starlike and convex functions, respectively. Further work regarding the function$\mathfrak{J}_{\kappa _{1},\kappa _{2}}^{\kappa _{3},m}(z)\ $Jκ1,κ2κ3,m(z)is underway and will be presented in a forthcoming paper.
An anatomically shaped medial meniscus prosthesis is able to partially restore the contact mechanics of the meniscectomized knee joint
Authors: van Minnen Branco S. , van der Veen Albert J. , van de Groes Sebastiaan A. W. , Verdonschot Nico J. J. , van Tienen Tony G. 
Published: September 2022

Abstract
Purpose
The aim of this study was to determine whether a flexible medial meniscus prosthesis is more capable of sharing loads with the direct tibiofemoral cartilage contact than the stiffer first-generation prosthesis. Additionally, the effect of the prosthesis on the tibial pressure distribution after total meniscectomy was investigated.

Methods
In an artificial knee joint, the relative amounts of load transferred through both meniscus prostheses and the direct tibiofemoral contact were assessed with pressure-sensitive sensors.
Additionally, six cadaveric knee joints were loaded in a physiological environment. Tibial contact pressures were measured with an intact native meniscus, after total meniscectomy and after implantation of the second-generation meniscus prosthesis.

Results
Whereas the first generation of the meniscus prosthesis transferred virtually all the load from femur to tibia, the second-generation prosthesis allowed for load sharing with the direct tibiofemoral contact.
No differences in load sharing were found between the native meniscus and the second-generation meniscus prosthesis. The prosthesis decreased peak and mean pressures on the medial tibial cartilage compared to meniscectomy. No significant differences in pressure were found between the native meniscus and the meniscus prosthesis.

Conclusions
The second-generation meniscus prosthesis presented in this study can share loads with the direct tibiofemoral contact, a characteristic that the first-generation prosthesis did not have.
The flexible meniscus prosthesis significantly reduces the contact pressures on the medial tibial plateau after total meniscectomy. Although the biomechanical performance of the native meniscus could not be reproduced completely, the meniscus prosthesis may have the potential to relieve post-meniscectomy pain symptoms.
Three-year follow-up of posterior chamber phakic intraocular lens with a central port design after deep anterior lamellar keratoplasty
Authors: Alfonso-Bartolozzi Belén , Lisa Carlos , Fernández-Vega-Cueto Luis , Baamonde Begoña , Madrid-Costa David , Alfonso José F. 
Published: September 2022

Abstract
Background
To evaluate clinical outcomes of the Visian implantable collamer lens (ICL) with a central port to correct myopia and astigmatism after deep anterior lamellar keratoplasty (DALK) for keratoconus throughout 3 years of follow-up.

Methods
This study included 20 eyes of 20 patients that underwent V4c ICL (13 eyes with a spherical ICL and 7 eyes with a toric ICL) implantation after DALK. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, intraocular pressure (IOP), endothelial cell density (ECD), and vault were analyzed.

Results
The mean UDVA improved from the preoperative 1.18 ± 0.33 logMAR to 0.25 ± 0.14 logMAR at 6 months after surgery (P < 0.0001) and remained unchanged throughout the whole follow-up (P = 0.4). All eyes gained lines of CDVA compared to preoperative values. At the last follow-up visit, all eyes achieved CDVA of 0.2 logMAR or better and 13 eyes (65%) 0.1 logMAR or better. At 6 months post-surgery, all eyes (100%) had a spherical equivalent within ± 1.50 D, and 19 (95%) within ± 1.00 D. The mean manifest spherical equivalent was stable over the postoperative follow-up (P = 0.25). No significant increase in IOP occurred in any case throughout the 3 years of follow-up. The loss in ECD from the preoperative baseline at the last follow-up visit was 2.27%.

Conclusions
The clinical outcomes suggest that the V4c ICL implantation for correction of myopia and regular astigmatism in post-DALK eyes was satisfactory in terms of effectiveness, safety, and stability during 3 years of follow-up.
Solving a running crab spider puzzle: delimiting Cleocnemis Simon, 1886 with implications on the phylogeny and terminology of genital structures of Philodromidae
Authors: Prado André Wanderley do , Baptista Renner Luiz Cerqueira , Schinelli Hector Baruch Pereira , Takiya Daniela Maeda 
Published: September 2022

Abstract
Background
Among the 16 Neotropical genera of Philodromidae, Cleocnemis has the most troublesome taxonomic situation. Remarkable morphological differences among several genera historically said to be related to Cleocnemis denote controversial notions and general uncertainty about the genus identity. Thus, to clarify the genus limits and contribute to the understanding of Neotropical Philodromidae, we conducted a morphological analysis, along with Bayesian Inference and Maximum Likelihood molecular phylogenetic analyses focusing on Cleocnemis and related genera of Thanatinae. All of the 14 species previously placed in Cleocnemis were studied, and eight of them included in the molecular analyses based on fragments of 28S rDNA, histone H3, 16S rDNA, and cytochrome oxidase I (COI).

Results
Cleocnemis was recovered as polyphyletic. Most of its species are distributed into six lineages allocated into five morphologically recognizable groups: Group I [Cleocnemis heteropoda], representing Cleocnemis sensu stricto and two new junior synonyms, Berlandiella and Metacleocnemis; Group II [Tibelloides bryantaecomb. nov., Tibelloides punctulatuscomb. nov., Tibelloides reimoserinom. nov., and Tibelloides taquaraecomb. nov.], representing Tibelloidesgen. rev., which was not recovered as monophyletic; Group III [Fageia moschatacomb. nov., Fageia roseacomb. nov.], representing the genus Fageia; Group IV [“Cleocnemis” lanceolata]; and Group V [“Cleocnemis” mutilata, “Cleocnemis” serrana, and “Cleocnemis” xenotypa]. Species of the latter two groups are considered incertae sedis. Cleocnemis spinosa is maintained in Cleocnemis, but considered a nomen dubium. Cleocnemis nigra is considered both nomen dubium and incertae sedis. We provide a redelimitation of Cleocnemis, redescription, neotype designation, and synonymy of type-species C. heteropoda. Taxonomic notes on composition, diagnosis, and distribution for each cited genus are also provided. Phylogenetic results support the division of Philodromidae into Thanatinae new stat. and Philodrominae new stat. and suggest expansion of their current compositions. Terminology of genital structures of Philodromidae is discussed.

Conclusions
Our results bring light to Cleocnemis taxonomy and enhance the understanding of the relationships within Philodromidae, especially through the assessment of neglected Neotropical taxa.
Anesthesia management in living-donor liver transplantation in a patient with carbamoyl phosphate synthetase deficiency: a case report
Authors: Matsushita Hiroki , Fujiyoshi Tetsushiro , Yoshimaru Koichiro , Matsuura Toshiharu , Mushimoto Yuichi , Karashima Yuji , Yamaura Ken 
Published: September 2022

Abstract
Background
Carbamoyl phosphate synthetase deficiency (CPS1D) is a urea-cycle disorder (UCD). We report successful perioperative management of pediatric living donor liver transplantation (LDLT) in a CPS1D patient.

Case presentation
A 10-year-old female patient with CPS1D underwent LDLT. Proper administration of dextrose 50% and 60 kcal/kg/day with l-arginine and l-carnitine resulted in the avoidance of intraoperative hyperammonemia induced by hypercatabolism. Serum ammonia level transiently increased to 61 mmol/L in the anhepatic phase and decreased to 44 mmol/L after reperfusion.

Conclusions
We suggest anesthesia management with administration of dextrose to avoid hyperammonemia during LDLT in patients with CPS1D.
The association of food insecurity and cardiometabolic risk factors was independent of body mass index in Iranian women
Authors: Hashemzadeh Maral , Teymouri Maryam , Fararouei Mohammad , Akhlaghi Masoumeh 
Published: September 2022

Abstract
Background
Investigations on food insecurity have shown that food insecurity is inversely associated with health. We examined the association of food insecurity and cardiometabolic risk factors in women living in Shiraz, Iran.

Methods
The cross-sectional study was performed on 190 females. Food insecurity was assessed by Household Food Insecurity Access Scale. Cardiometabolic risk factors including anthropometric characteristics, blood pressure, and serum glucose and lipids were measured. Metabolic syndrome score was calculated according to the criteria described for Iranian adults. The association of food insecurity and cardiometabolic risk factors was assessed by linear regression.

Results
The prevalence of food security, and mild, moderate, and severe food insecurity was 42.6%, 40.5%, 15.8%, and 1.1%, respectively. Cardiometabolic risk factors worsened with increasing severity of food insecurity. Among the risk factors, body mass index (BMI) had the strongest association with food insecurity. After controlling demographic factors and BMI, fasting blood glucose, triglycerides, total, LDL, and HDL cholesterols, and metabolic syndrome score still showed significant associations with food insecurity (P < 0.01) but systolic and diastolic blood pressure were no longer associated with food insecurity after adjustment for BMI.

Conclusion
Overall, although BMI was strongly associated with food insecurity, cardiometabolic risk factors including blood glucose, triglycerides, total, HDL, and LDL cholesterols, and metabolic syndrome score were associated with food insecurity independent of BMI, suggesting that other factors such as lifestyle and diet may have contributed to the exacerbated cardiometabolic risk in food insecure participants of this study. Future studies need to clarify underlying factors in the association of food insecurity and cardiometabolic risk factors.