bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversity of Siphonaria Sowerby I, 1823 (Gastropoda, Siphonariidae) in the Seychelles Bank and beyond
Authors: Ossenbrügger Holger , Neiber Marco T. , Hausdorf Bernhard 
Published: November 2022

AbstractMolecular phylogenetic studies have shown that the characters of the reduced shell of the false limpets of the genus Siphonaria Sowerby I, 1823 are highly variable and often insufficient for species delimitation. The taxonomy and distribution of Siphonaria in the Indian Ocean are poorly known. We sampled Siphonaria in the Seychelles Bank to check the occurrence of recorded species using DNA sequences and to study the paths through which Siphonaria species have colonised the Seychelles Bank by reconstructing their phylogenetic relationships. Analyses of a dataset comprising 16 S rRNA gene sequences of 33 specimens from the Seychelles Bank and 300 additional Siphonaria sequences from other regions from GenBank with various methods for species delimitation resulted in 19–102 primary species hypotheses. Assemble Species by Automatic Partitioning provided a conservative estimate of the species number (42) in which several indisputable species were lumped. The results of Automatic Barcode Gap Discovery depended strongly on the assumed prior maximum intraspecific divergence, whereas the tree‐based methods Generalised Mixed Yule Coalescent and Poisson Tree Processes resulted in high overestimates. The specimens from the Seychelles Bank represent three clades, belonging to the Siphonaria ‘atra’ group, the Siphonaria ‘normalis’ group and a possibly undescribed species recorded previously only from Hainan. At least two of the three species recorded from the Seychelles Bank came from the east, i.e., from the Coral Triangle in the Indo‐Australian Archipelago, the region with the highest marine biodiversity worldwide. A major transport mechanism across the Indian Ocean was probably the South Equatorial Current.
Irish Para Report Card on Physical Activity of Children and Adolescents With Disabilities
Authors: Ng Kwok , Healy Sean , O’Brien Wesley , Rodriguez Lauren , Murphy Marie , Carlin Angela 
Published: November 2022

For the first time, data on children and adolescents with disabilities in Ireland are reported based on the Active Healthy Kids Global Alliance Para Report Card methodology. The most recent data from the last 10 years were used in the grading process (A+ to F), and indicators with insufficient data were graded as incomplete. Of the 10 indicators from the Global Matrix Para Report Cards, grades were assigned to Overall Physical Activity (F), Organized Sport (D), Active Transport (D−), Sedentary Behaviors (D−), Family & Peers (C), School (C−), Community & Environment (B−), and Government (B). Irish disability sport organizations were invited to assess the research-led audit and provided commentary around the final grading. The contextual discussion of the grades is presented through the lens of strengths, weaknesses, opportunities, and threats with the purpose being to provide direction for the reduction of physical activity disparities among children with disabilities.
Spatially targeted brain cancer immunotherapy with closed-loop controlled focused ultrasound and immune checkpoint blockade
Authors: Lee Hohyun , Guo Yutong , Ross James L. , Schoen Scott , Degertekin F. Levent , Arvanitis Costas 
Published: November 2022

Despite the challenges in treating glioblastomas (GBMs) with immune adjuvants, increasing evidence suggests that targeting the immune cells within the tumor microenvironment (TME) can lead to improved responses. Here, we present a closed-loop controlled, microbubble-enhanced focused ultrasound (MB-FUS) system and test its abilities to safely and effectively treat GBMs using immune checkpoint blockade. The proposed system can fine-tune the exposure settings to promote MB acoustic emission–dependent expression of the proinflammatory marker ICAM-1 and delivery of anti-PD1 in a mouse model of GBM. In addition to enhanced interaction of proinflammatory macrophages within the PD1-expressing TME and significant improvement in survival (
P
< 0.05), the combined treatment induced long-lived memory T cell formation within the brain that supported tumor rejection in rechallenge experiments. Collectively, our findings demonstrate the ability of MB-FUS to augment the therapeutic impact of immune checkpoint blockade in GBMs and reinforce the notion of spatially tumor-targeted (loco-regional) brain cancer immunotherapy.
The P-V phase transition of the FRW universe
Authors: Kong Shi-Bei , Abdusattar Haximjan , Yin Yihao , Zhang Hongsheng , Hu Ya-Peng 
Published: November 2022

AbstractWe define thermodynamic pressure P by work density W as the conjugate quantity of thermodynamic volume V from field equation. We derive the equations of state P=P(V, T) for the Friedmann–Robertson–Walker (FRW) universe in Einstein gravity and a modified gravity respectively. We find that the equation of state from Einstein gravity shows no P-V phase transition, while the equation of state from the modified gravity does, where the critical exponents are the same as those in mean field theory.
Self-tuning inflation
Authors: Petriakova Polina , Rubin Sergey G. 
Published: November 2022

AbstractWe develop an inflationary model without small parameters on the basis of multidimensional f(R) gravity with a minimally coupled scalar field. The model is described by two stages of space expansion. The first one begins at energy scales about the D-dimensional Planck mass and ends with the de Sitter metric of our space and the maximally symmetric extra dimensions. In the following, the quantum fluctuations produce a wide set of inhomogeneous extra metrics in causally disconnected regions quickly generated in the de Sitter space. We find a specific extra space metric that leads to the effective Starobinsky model that fits the observational data.
Saturation spectroscopy of R(0), R(2) and P(2) lines in the (2-0) band of HD
Authors: Cozijn F. M. J. , Diouf M. L. , Ubachs W. 
Published: November 2022

AbstractLamb-dips of R(0), R(2) and P(2) rovibrational transitions in the (2-0) overtone band of the HD molecule are measured at cryogenic temperatures using the technique of NICE-OHMS spectroscopy. Resulting transition frequencies are $$214\,905\,335\,240\,(100)$$

214

905

335

240

(
100
)

kHz for R(0), $$219\,042\,856\,794\,(150)$$

219

042

856

794

(
150
)

kHz for R(2) and $$206 \,898 \,802\,150 \,(150)$$

206

898

802

150

(
150
)

kHz for P(2). Small, but systematic deviations (at 1.7$$\sigma $$
σ
level) are found from advanced ab initio calculations, supporting results from previous studies probing other lines in the (2-0) band. From a combination difference between the R(0) and P(2) lines, an accurate value for rotational-level spacing in the $$v=0$$

v
=
0

ground state is determined, of $$\Delta _{(J=2)-(J=0)}= 8\,006\,533\,168\,(26)$$

Δ

(
J
=
2
)
-
(
J
=
0
)

=
8

006

533

168

(
26
)

kHz, well in agreement with theory (at 0.6$$\sigma $$
σ
). Based on the observation of the dispersive line shape of R(0), the status of proposed models for the elusive line shapes of saturated transitions in HD is discussed.
Desfecho clínico de pessoas com diabetes infectadas pelo SARS-CoV-2 que desenvolveram Síndrome Respiratória Aguda Grave, Brasil.
Authors: Andrade Caroline Marques de , Geumaro Eduardo Alexandre , Borges Felipe Abrantkoski , Jacomossi Ângelo César Fernandes 
Published: November 2022

Objetivo: Comparar os desfechos clínicos de pessoas com e sem Diabetes Mellitus tipo 2 (DM 2), infectadas pelo SARS-CoV-2, que desenvolveram Síndrome Respiratória Aguda Grave (SRAG) no Brasil. Métodos: Trata-se de um estudo transversal realizado a partir de análise da ficha de notificação compulsória de Síndrome Respiratória Aguda Grave Hospitalizado, obtidas no DATASUS. Foram analisados homens e mulheres com e sem DM2, infectados pelo SARS-CoV-2 e notificados como SRAG no período de fevereiro de 2020 a maio de 2021. Foram identificados os desfechos: hospitalização, admissão em Unidade de Terapia Intensiva (UTI) e óbito. Em seguida, a porcentagem de cada desfecho entre pessoas com DM2 foi comparada com a de pessoas não-diabéticas infectadas no mesmo período, utilizando o teste de Qui-Quadrado, com intervalo de confiança de 95%. Resultados: De um total de 384.805 pacientes, 111.046 eram diabéticos e 273.759 não diabéticos. Entre os diabéticos, 98.2% foram hospitalizados, 43.7% admitidos em UTI e 44.6% evoluíram a óbito. Enquanto entre os não-diabéticos, 97.3% necessitaram de hospitalização, 37.2% foram admitidos em UTI e 35.7% evoluíram a óbito. Após a análise com o teste de Qui-Quadrado, nos desfechos analisados foi encontrada uma diferença estatística significante (p<0.001) entre os grupos. Conclusão: A presença de DM 2 esteve associada a um pior prognóstico da COVID-19, quando comparada a pessoas sem DM2 na população brasileira. Entretanto, são necessários mais estudos para estabelecer a causalidade e elucidar a fisiopatologia dessa associação.
Análise epidemiológica dos acidentes por escorpiões em um município do Triângulo Mineiro
Authors: Motta Ana Laíza Ferreira , Arruda Anna Myrian Vieira , Melo Guilherme Cerva de , Oliveira Stefan Vilges de 
Published: November 2022

Introdução: Minas Gerais é o estado brasileiro com a maior taxa de escorpionismo, foram registrados 223.033 casos entre 2010-2017, dessa forma se faz necessária reflexões sobre como reduzir esse problema de saúde pública. Objetivo: o presente estudo visa descrever o perfil epidemiológico de acidentes oriundos do escorpionismo ocorridos no município de Patos de Minas (MG) no período de 2013 a 2017 e desenvolver um projeto de intervenção a partir do mesmo. Métodos: Primeiramente, o número de acidentes por animais peçonhentos em Patos de Minas (MG) foi analisado utilizando-se as variáveis que contemplam a ficha de notificação e investigação do SINAN, disponíveis no DATASUS. Além disso, foram utilizadas duas bases de dados, CAFE e PUBMED, para o referencial teórico, com os seguintes descritores: escorpião, Minas Gerais, envenenamento e prevenção e suas respectivas traduções para o inglês. Resultados: Acidentes por picada de escorpião foram os mais registrados dentre os animais peçonhentos, além de terem aumentado anualmente no período de estudo, atingindo, em 2017, o número de 274 casos notificados. Ademais, a frequência dos acidentes foi registrada em maior número no sexo masculino (51,18%) e a faixa etária mais atingida foi entre 20 a 39 anos (32,64%). Observa-se também que os acidentados foram classificados como casos leves e atendidos na primeira hora da picada (97,92%), com nenhum óbito no período. Os resultados encontrados estão em concordância com as referências utilizadas, sendo mais comum, em estudos, o registro de casos leves, em adultos, do sexo masculino. Para o embasamento da proposta de intervenção, foram utilizados cinco artigos e baseado neles propõem-se o desenvolvimento de ações preventivas, corretivas do ambiente e educacionais. Conclusão: Com o estudo, foi possível identificar o público-alvo das propostas de intervenção e quando elas deveriam ser intensificadas, para tentar conter, assim, o aumento constante dos casos de escorpionismo no município analisado.
Endovascular Thrombectomy Versus Best Medical Therapy for Late Presentation Acute Ischemic Stroke With Proximal Large‐Vessel Occlusion Selected on the Basis of Noncontrast Computed Tomography: A Retrospective Analysis of 2 Prospectively Defined Cohorts
Authors: Dhillon Permesh Singh , Butt Waleed , Jovin Tudor G. , Podlasek Anna , McConachie Norman , Lenthall Robert , Nair Sujit , Malik Luqman , Krishnan Kailash , Chiavacci Iacopo , Mehedi Farhan , Hong Timothy , Selva Harriwin , Dineen Robert A. , England Timothy J. 
Published: November 2022

Background
The efficacy and safety of endovascular thrombectomy (EVT) >6 hours from acute ischemic stroke (AIS) onset for patients selected without computed tomography (CT) perfusion or magnetic resonance imaging is undetermined in routine clinical practice.

Methods
In this single‐center study, we identified consecutive late‐presenting patients with AIS who were eligible for EVT on the basis of noncontrast CT/CT angiography (without CT perfusion or magnetic resonance imaging) using an Alberta Stroke Program Early CT Score of ≥6, >6 hours from stroke onset, between January 2018 and March 2022. During the study period, EVT capacity limitations meant EVT‐eligible patients presenting out of regular working hours, consistently received best medical management (BMM). Functional outcomes (modified Rankin Scale at 90 days), symptomatic intracranial hemorrhage, and mortality at 90 days were compared between patients receiving EVT or BMM following multivariable adjustment for age, sex, baseline stroke severity, Alberta Stroke Program Early CT Score, onset‐to‐neuroimaging time, intravenous thrombolysis, and clot location.

Results

Among 4802 patients with AIS, 150 patients (3.1%) presenting beyond 6 hours of onset were eligible for EVT: 74 (49%) treated with EVT and 76 (51%) with BMM. Compared with the BMM group, patients treated with EVT had significantly improved functional outcome (modified Rankin Scale) (adjusted common odds ratio, 2.23 [95% CI, 1.18–4.22];
P
=0.013), and higher rates of functional independence (modified Rankin Scale ≤2; 39.2.% versus 9.2%; adjusted odds ratio, =4.73 [95% CI, 1.64–13.63];
P
=0.004). No significant difference was observed between the EVT and BMM groups in the symptomatic intracranial hemorrhage (5.4% versus 2.6%;
P
=0.94) or mortality (20.2% versus 47.3%;
P
=0.16) rates, respectively.

Conclusion
In routine clinical practice, of the 3.1% of patients in our AIS population presenting after 6 hours from stroke onset who were deemed eligible for EVT by noncontrast CT/CT angiography alone, those treated with EVT achieved significantly improved functional outcome, compared with patients treated with BMM only. No significant differences were noted between the 2 groups with respect to symptomatic intracranial hemorrhage and mortality. While confirmatory randomized trials are awaited, these findings suggest that EVT is effective and safe when performed in patients with AIS selected without CT perfusion or magnetic resonance imaging >6 hours from stroke onset.
Pauline Epistles as Affective Technologies: Liberating Literary Form and the Letter to Philemon
Authors: Dinkler Michal Beth 
Published: November 2022

Abstract
This article explores the affective potentials of the Pauline epistles by extending a proposal that I made in my book, Literary Theory and the New Testament. There, I suggested that we conceive of epistles as meaning-bearing beings that give rise to what I called epistolary embodiment. Here, I seek to create space for the inherent precarity of epistolary communication by exploring the uncontrollable interstices between affect, emotion, embodiment, and cognition. How do the Pauline letters function as affective technologies – that is, as messy mechanisms for the art, skill, craft (the technē) of reflecting, evoking, and processing affects? Engaging a range of interlocutors outside of biblical studies (e.g., Ahmed, Mullaney, Gallop, Felski), I use the letter to Philemon as a case study for exploring how biblical scholars might embrace the ambivalences that mark all epistolary communication.
Toward Feeling Fragments: Melancholic Migrants and Other Affect Aliens in the Philippian and Corinthian Assemblies
Authors: Marchal Joseph A. 
Published: November 2022

Abstract
Grief and trauma mark both the ancient past and the present, while melancholia reflects the possibilities for holding on in both contexts. In order to vary and multiply our approaches to people and places touched by loss, biblical scholars could get a different feel for the potentials of melancholia as examined in affect, queer, and critical race theories. While Pauline letters often aim to convert grief away from pain and trauma, the pre-Pauline materials within them (specifically, the slogans in 1 Corinthians and the Christ-hymn in Philippians) index a communal melancholia, refusals to “get over it” or relinquish the other and/as lost object(s). Though the other affect aliens in the assembly communities are moving within colonized contexts shaped by layered sediments of insidious trauma, their slogans and hymns assemble contingent and temporary fragments, modes of negotiating difficult conditions, of loss and death, enslavement and exploitation, unwanted touch and ongoing suffering – without forgetting.
Corinthian Ignorance: Knowledge-Language and the Cultivation of Anxious Affects in 1 Corinthians
Authors: Bell Brigidda 
Published: November 2022

Abstract
The Corinthian assembly has been characterized by scholarship as full of anxieties that Paul writes to appease: anxieties about ritual impurity (1 Cor. 5:1–13), death (15:12–34), social relations (7:1–24), and other matters that occasion social conflict within the group. Paul, however, also writes in ways that evoke and fan anxiety, particularly through his appeals to knowledge. Knowledge is a central theme throughout 1 Corinthians, and in his use of knowledge-language Paul highlights a distinct lack or insufficiency in the knowledge of his audience. Mediated through the affective technology of the letter, the repeated impressions of unknowing, ignorance, and lack have the potential to coalesce in their audience into negative feelings around the threat of incurring shame. While Paul may rhetorically employ this language to position himself as a broker of right knowledge, the consequences of his rhetorical choices may emerge in his audience as a distinct set of anxious feelings read within the affective script of Roman verecundia.
Embryogeny of Bosmina longirostris (O. F. Müller, 1785) (Bosminidae) confirms a close relationship to the superfamily Eurycercoidea (Branchiopoda, Cladocera, Anomopoda)
Authors: Uhlik Marcin E. , Brzeziński Tomasz 
Published: November 2022

Abstract
The embryonic stages of the anomopod Bosmina longirostris of the family Bosminidae were elucidated by scanning electron microscopy. Along with the corresponding stages of Bosmina coregoni described by Kotov (2001), these findings have enabled a comparison to Dunhevedia crassa, as a representative species of the family Chydoridae, and to Eurycercus lamellatus of the family Eurycercidae. In general, the developmental patterns are similar in these four species, particularly from blastulation to the first instar. The principal difference during embryogenesis is that in D. crassa and B. longirostris five thoracopods (six in E. lamellatus) are differentiated already with endo- and exopodites.
On Cryptocoeloma haswelli Rathbun, 1923 (Decapoda, Brachyura, Pilumnidae): taxonomy and first record from Hong Kong and Taiwan
Authors: Ng Peter K. L. , Wong Kingsley J. H. , Tsang Chandler Tsz To , Tsang Ling Ming 
Published: November 2022

Abstract
The poorly known pilumnid crab Cryptocoeloma haswelli Rathbun, 1923, is redescribed and figured at length on the basis of fresh specimens from Hong Kong and Taiwan, both of which constitute new local records. The male is redescribed and figured as the only previous account of it had been based on a gynandromorph. The species is also compared in detail with Heteropilumnus fimbriatus (H. Milne Edwards, 1834) with which it has been previously confused.
Gradually elevated salinities alter the haemolymph metabolic profile and nitrogenous wastes of the mature Chinese mitten crab, Eriocheir sinensis (Decapoda, Varunidae)
Authors: Wang Ruifang , Shen Chenchen , Feng Guangpeng , Zhuang Ping , Huang Xiaorong , Zhang Tao 
Published: November 2022

Abstract
To understand the metabolic adjustments and nitrogen excretion in haemolymph of mature Eriocheir sinensis during the reproductive migration from fresh water to seawater, haemolymph metabolic variations and nitrogenous wastes were determined after gradual acclimation of females and males from fresh water to different salinities (7, 14, 21, 28 and 35). Total protein content in both female and male crabs was reduced with increased salinity. The contents of lipids including triglyceride and cholesterol significantly decreased at salinities of 0-21, suggesting the lipids of E. sinensis might be mobilized to produce energy for osmoregulation and gonad development at a different salinity. Interestingly, the lipid levels in the females were higher than those in the males, implying the females need to store more lipids to prepare for reproduction. The glucose level was low in this study, which was related to the diet with high protein. Haemolymph urea and uric acid level together decreased at first and then increased, indicating that E. sinensis could regulate the nitrogen excretion pattern by inhibiting or activating ureogenesis and uricogenesis to acclimate to a different osmotic environment. Notably, the females might be more tolerant to salinity increase and have a faster metabolic reorganization than males. These facts could indicate that a different strategy has been employed in mature E. sinensis when encountering salinity stress during the reproductive migration form fresh water to seawater.
A new species of pea crab of the genus Indopinnixa Manning & Morton, 1987 (Decapoda, Brachyura, Pinnotheridae) from Flores in eastern Indonesia, with a key to the genus
Authors: Ng Peter K. L. , Rahayu Dwi Listyo 
Published: November 2022

Abstract
A new species of pinnotherid crab, Indopinnixa latimerus n. sp. is described on the basis of a female specimen from the island of Flores in Indonesia. This new species resembles I. oryza Naruse & Maenosono, 2012 in having a subovate carapace, without any protuberance on the lateral margin, and a distally expanded merus of the fourth ambulatory leg, but differs in the shape of the frontal margin, and the density of the setation of the carapace and chelipeds. A key to the nine known species of Indopinnixa is provided.
The Charism Scale
Authors: Pollefeyt Didier , van Rooij Fons , Bouwens Jan 
Published: November 2022

Abstract
Educational Charismic traditions, like Marist Education in the Champagnat tradition, among many other charisms, are different ways of ‘enfleshing’ and ‘flavouring’ the Gospel of Christ. They are about the incarnation of the Christian message, a particular expression of what it means to be Christian within the context of one’s own time, place and culture. What are the characteristics, and particular emphases, of such ‘enfleshments’? The Charism Scale is a new empirical survey instrument designed to assist schools to explore the degree to which their foundational charisms exist and the way they take shape. The multi-variate attitude scale is based on five empirically confirmed dimensions to which various educational charismic traditions respond in different ways. It is ‘in the mix’ that the particularities of each charismic tradition emerge. This empirical data enables school communities to identify and strengthen the particular charismic flavour they bring to the Catholicity of the school.
In Signum Benevoli Affectus IV: Menasseh ben Israel’s Album Inscription for Hermannus Jacobi
Authors: Postma Ferenc , Verheij Arian 
Published: November 2022

Abstract
In 1650, Menasseh ben Israel entered an inscription in the album amicorum owned by Hermannus Jacobi from Hanover. This article, the fourth in a series on Menasseh’s album inscriptions, comprises a biographical sketch of Jacobi, followed by a photograph, a transcription, a translation, and an analysis of the inscription itself. Reference is made as well to Menasseh’s inscription in the album amicorum, now lost, of Henricus Schmettavius / Heinrich Schmettau, a student of theology from Silesia.