bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular characterization and reclassification of a 1.18 Mbp DMD duplication following positive carrier screening for Duchenne/Becker muscular dystrophy
Authors: Zepeda‐Mendoza Cinthya J. , Bontrager Jordan E. , Fisher Camille F. , McDonald Amber , George‐Abraham Jaya K. , Hasadsri Linda 
Published: July 2022

AbstractA 2‐month‐old male patient harboring a duplication of DMD exons 1–7 classified as pathogenic by an outside institution presented with mildly elevated creatine phosphokinase (CK); molecular breakpoint analysis by our laboratory reclassified the duplication as likely benign. To date, proband continues to develop normally with decreased CK, further supporting our reclassification.
Angiographic retrograde filling of all left coronary arterial branches in a patient with chronic total occlusion of left main coronary artery
Authors: Nenekidis Ioannis , Samanidis George , Kanakis Meletios , Contrafouris Constantinos , Karavana Eleni , Papakonstantinou Nikolaos , Chatzis Andrew , Perreas Konstantinos 
Published: July 2022

AbstractA 81‐year‐old female patient was referred in our hospital with episodes of pulmonary edema and had an isolated chronic total occlusion of the left main coronary artery. Coronary angiogram showed total occlusion the left main and filling the left coronary system by collaterals from the right coronary artery.
Cuboid fracture: An extremely rare cause of limping in a 2‐year‐old child
Authors: Delniotis Ioannis , Nitis Georgios , Gekas Christos , Leidinger Benedikt 
Published: July 2022

AbstractThe purpose of this case report is to raise awareness of an extremely rare cause of limping, in young children. Clinicians should have a high index of suspicion of a possible cuboid fracture when evaluating a young child who presents with limping.
A long‐standing case of desmoplastic fibroblastoma of the face
Authors: Singh Arpita , Ghosh Snehashish , Shivakotee Satyapriya , Dhungel Safal , Raj A. Thirumal , Patil Shankargouda 
Published: July 2022

AbstractThe present case report depicts an unusually large desmoplastic fibroblastoma. The diagnosis of the lesion appears to be deceptive clinically. The purpose of this case image is to highlight its size and presenting symptoms, which could easily be mistaken for an odontogenic, salivary gland, or a soft tissue neoplasm.
Co2+‐Doped Porous Ni(OH)2 Nanosheets Electrode for Selective Electrocatalytic Oxidation of Methanol at High Current Densities
Authors: Ming Liying , Wu Xiao‐Yuan , Wang Sa‐Sa , Wu Weiming , Lu Can‐Zhong 
Published: July 2022

AbstractCo2+‐doped Ni(OH)2 nanosheets were grown on porous Ni foam by a simple electrodeposition method. The obtained samples were used as porous electrodes for selective electrocatalytic oxidation of methanol to formate in NaOH aqueous solution. The results indicated the oxidizing abilities of the as‐prepared electrodes could be regulated by the doping content of Co2+ for the electrooxidation of methanol, in which the electrode with a Co2+ doping content of 10 mol % required a lowest potential of ∼1.32 V vs. RHE to achieve a current density of 100 mA cm−2 as compared with other electrodes. And the doping of Co2+ helped boosting the Faradic efficiency for the electrocatalytic oxidation of methanol. Moreover, the electrooxidation of methanol for the production of formate (Faradic efficiency ≥96.5 %) with the simultaneous generation of hydrogen was easily implemented in a two‐electrode configuration at high current densities (100–500 mA cm−2). The results of the durability test further revealed that the 10 mol % Co2+‐doped Ni(OH)2 electrode exhibited an outstanding stability for the electrocatalytic oxidation of methanol in the present system.
Impact of Nanotechnology on the Realm of Stem Cells and Regenerative Medicine
Authors: Dash Saumya , Shakeel Adeeba , Mohanty Sujata 
Published: July 2022

AbstractThe intersection of very different, yet complementary fields, stem cells and nanotechnology, has led to the opening of new horizons in the area of research, giving new hopes, better strategies, and a boost to regenerative medicine, nanotherapeutics, and tissue engineering. Harnessing the stem cell's ability to self‐renew and differentiate into specific types of functional cells and the unique physico‐chemical properties of the nanomaterials, researchers have optimized the interactions of these with the biological milieu to overcome the hurdles of conventional cell‐based therapies. Here, we highlight and outline various types of nanomaterials and their well‐established significance in redefining the future of human medicine through influencing stem cell research targeting illness of important human organs.
An efficient framework for the similarity prediction with query recommendation in E‐learning system
Authors: Prasad Vedavathi Nagendra , Kureekatil Muthappa Anil Kumar 
Published: July 2022

SummaryA novel model of data similarity estimation and clustering method is proposed in this article to retrieve the relevant data with the best matching in big data processing. An advanced model of graph distance pattern (GDP) method with lexical subgroup (LS) system is used to estimate the similarity between the query data and the entire database. With the help of neural network, the relevancy of feature attributes in the database are predicted and matching index is sorted to provide the recommended data for given query data. This was achieved by using the correlated sim‐neural network (CSNN). This is an enhanced model of neural network technology to find the relevancy based on the correlation factor of feature set. The training process of CSNN classifier is carried by estimating the correlation factor of the attributes of dataset. These are forms as the clusters and paged with proper indexing based on the LS parameter of similarity metric. The results obtained by the proposed system for recall, precision, accuracy, error rate, F‐measure, kappa coefficient, specificity, and MCC are 0.98, 0.98, 0.97, 0.03, 0.99, 0.991, 0.986, and 0.984, respectively.
Efficient Photocatalytic H2 Evolution by Hexaniobate Nanosheets Grafted with Copper Nanoclusters
Authors: Nascimento Nunes Barbara , Bahnemann Detlef W. , Otavio T. Patrocinio Antonio 
Published: July 2022

AbstractThe front cover artwork is provided by Dr. Leandro A. Faustino from the Federal University of Uberlandia (Brazil). The image shows a hexaniobate nanosheet modified with copper nanoclusters. Copper species exhibit different oxidation states on the hexaniobate surface, starting from Cu2+, which is then reduced to Cu+ and Cu0 under irradiation. The good interaction between copper and the hexaniobate promotes an efficient photocatalytic H2 evolution. Read the full text of the Research Article at 10.1002/cptc.202100272.
Assessing the effect of complex ground types on ground‐dwelling arthropod movements with video monitoring: Dealing with concealed movements under a layer of plant residues
Authors: Collard Blanche , Tixier Philippe , Carval Dominique , Lavigne Claire , Delattre Thomas 
Published: July 2022

AbstractUnderstanding the effect of ground types on foraging movements of ground‐dwelling arthropods is a key step to managing their spatial distribution as required for successful conservation biological control. Indeed, fine movements at the centimeter scale can strongly influence the foraging ability of pest predators. However, because radio frequency identification or harmonic tracking techniques are not yet suitable for small species and video tracking focuses on uniform and light backgrounds, foraging movements have rarely been studied in relation to ground types. We present a method to track a ground‐dwelling arthropod (the earwig Euborellia caraibea) at night, walking on two contrasted ground types: bare soil and soil partly covered with a stratum of banana plant residues allowing individuals to hide periodically. The tracking of individuals within these ground types was achieved by infrared light, tagging individuals, video treatments, and semi‐automatic cleaning of trajectories. We tested different procedures to obtain segments with identical durations to quantify speeds and sinuosities. These procedures were characterized by the junction time gap between trajectory fragments, the rediscretization time of trajectories, and whether or not to use interpolation to fill in missing points in the trajectories. Earwigs exhibited significantly slower and more sinuous movements on soil with banana plant residues than on bare soil. Long time gaps for trajectory junction, extended rediscretization times, and interpolation were complementary means to integrate concealed movements in the trajectories. The highest slowdown in plant residues was detected when the procedure could account for longer periods under the residues. These results suggest that earwigs spent a significant amount of time concealed by the residues. Additionally, the residues strongly decreased the earwigs' movement. Since the technical solutions presented in this study are inexpensive, easy to set up, and replicate, they represent valuable contributions to the emerging field of video monitoring.
Potassium Ion‐selective Electrode with a Sensitive Ion‐to‐Electron Transducer Composed of Porous Laser‐induced Graphene and MoS2 Fabricated by One‐step Direct Laser Writing
Authors: Thuy Nguyen Thi Dieu , Zhao Guo , Wang Xiaochan , Awuah Emmanuel , Zhang Litao 
Published: July 2022

AbstractIn this study, an ion‐selective electrode with a sensitive ion‐to‐electron transducer composed of porous laser‐induced graphene (LIG) and MoS2 (LIG‐MoS2/ISE) was fabricated to measure the potassium ion concentration in a greenhouse nutrient solution for soilless culture. Additionally, a more effective and low‐cost method was proposed for the large‐batch production and manufacture of potassium ion‐selective electrodes (K+‐ISEs) using the direct laser writing technique, which differs considerably from existing methods. Moreover, the sensing mechanism of the proposed LIG‐MoS2/ISE for potassium ion detection was investigated. The morphology and physical properties of the LIG‐MoS2/SC‐K+‐ISEs were studied by X‐ray diffraction (XRD), scanning electron microscopy (SEM), Raman spectroscopy and energy‐dispersive spectroscopy. Potentiometric measurements, chronopotentiometry, potentiometric water layer tests, cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to evaluate the analytical performance of the newly developed K+‐ISEs. A Nernstian slope of 30.1 mV/decade for the activity of potassium ions in a concentration range from 10−7 to 10−2 M was determined. The EIS and chronopotentiometry results revealed that the LIG‐MoS2/SC‐K+‐ISE had a larger resistance and double‐layer capacitance than the LIG/SC‐K+‐ISE. The ion‐selective membrane (ISM) and solid‐contact layer did not have any water film between them, according to the potentiometric water layer test. The results proved that the LIG‐MoS2 nanocomposite could possibly be used as a sensitive ion‐to‐electron transducer to fabricate K+‐ISEs. The K+‐ISE fabrication method using the direct laser writing technique had a higher efficiency, enabling its broad application prospects in agriculture.
Evaluation of the impact of pH of the reaction mixture, type of the stirring, and the reagents' concentration in the wet precipitation method on physicochemical properties of hydroxyapatite so as to enhance its biomedical application potential
Authors: Głąb Magdalena , Kudłacik‐Kramarczyk Sonia , Drabczyk Anna , Kordyka Aleksandra , Godzierz Marcin , Wróbel Paweł S. , Tomala Agnieszka , Tyliszczak Bożena , Sobczak‐Kupiec Agnieszka 
Published: July 2022

AbstractHydroxyapatite (HAp) constitutes a significant inorganic compound which due to its osteoinductivity, osteoconductivity as well as the ability to promote bone growth and regeneration is widely applied in development of biomaterials designed for bone tissue engineering. In this work, various synthesis methodologies of HAp based on the wet precipitation technique were applied, and the impact of pH of the reaction mixture, the concentration of individual reagents as well as the type of stirring applied (mechanical/magnetic) on the properties of final powders was discussed. Spectroscopic methods (Fourier transform infrared, Raman) and X‐ray diffraction allowed to verify the synthesis parameters leading to obtaining calcium phosphate with 96% HAp in phase which indicated higher homogeneity of obtained powder (93.4%) than commercial HAp. Powders' morphology was evaluated using microscopic techniques while specific surface area was determined via Brunauer–Emmett–Teller analysis. Particle size distribution, porosity of powders, and stability of HAp suspensions were also characterized. It was proved that synthesis at pH = 11.0 using mechanical stirring resulted in calcium phosphate with a high phase homogeneity and homogeneous pore size distribution (6–20 nm). Moreover, obtained HAp powder showed 71.8% more specific surface area than commercial material—that is, 110 m3/g for synthetic HAp and 64 m3/g in the case of commercial powder—which, in turn, is significant in terms of its potential application as carrier of active substances. Thus it was demonstrated that by applying appropriate conditions of HAp synthesis it is possible to obtain powder with properties enhancing its application potential for medical purposes.
Does internationalization matter for corporate social performance of Chinese firms?
Authors: Wu Renhong , Kim Minho 
Published: July 2022

AbstractThe purpose of this paper is to explore the relationship between the internationalization of Chinese firms and their corporate social performance (CSP), a topic that remains largely unexplored for Chinese firms. Based on a sample of 325 firms listed on the China A‐shares market from 2010 to 2017, we find a positive relationship between the degree of internationalization (DOI) and CSP of Chinese firms. A positive relationship is also confirmed between corporate financial performance (CFP) and CSP in Chinese firms. However, we find that the interaction between CFP and DOI correlates negatively with CSP, indicating that during internationalization, CFP might not be conducive to improving CSP. Most listed firms in China are state‐owned enterprises (SOEs), and we find that their CSP is inferior to that of non‐SOEs. Finally, we find that hiring one of the four major accounting firms to conduct audits is conducive to a significant improvement in CSP. Managerial and policy implications derived from the results are discussed.
Novel Gd2O3/SrFe12O19@Schiff base chitosan (Gd/SrFe@SBCs) nanocomposite as a novel magnetic sorbent for the removal of Pb(II) and Cd(II) ions from aqueous solution
Authors: Jasim Saade Abdalkareem , Abdelbasset Walid Kamal , Hachem Kadda , Kadhim Mustafa M. , Yasin Ghulam , Obaid Maithm A. , Hussein Baydaa Abed , Lafta Holya A. , Mustafa Yasser Fakri , Mahmoud Zaid Hameed 
Published: July 2022

AbstractIn this work, novel Gd2O3/SrFe12O19@Schiff base chitosan (Gd/SrFe@SBCs) nanocomposite was prepared, and characterized using FT‐IR, XRD, DSC, VSM, FE‐SEM, X‐ray energy dispersive spectrum (EDS), and map analyses. All results confirm that the Gd2O3/SrFe12O19 nanocomposite/Schiff base chitosan was successfully prepared. EDS and map analyses predict that all elements are well distributed to the compound. VSM shows that the title compound has high saturation magnetic of 17.35 emu/g with high coercivity of 4,664 Oe. In addition, Gd/SrFe@SBCs were used as new adsorbents to the removal of Pb(II) and Cd(II) ions from aqueous solution, and results confirm that the removal efficiency of Pb(II) (98%) is higher than Cd(II) (78%) ion. At best conditions, the maximum adsorption capacity for Pb(II) is 183.7 and for Cd(II) is 146.2 mg/g. Reusability results show that the adsorption efficiency of Gd/SrFe@SBCs remained above 93% for Pb(II) and 71% for Cd(II) after five adsorption/desorption cycles. The effect of coexisting cation and anions was studied and confirm that the Gd/SrFe@SBCs had selective adsorption toward Pb(II). According to these results, we proposed that Gd/SrFe@SBCs studied as a sorbent to removal of other heavy metal ions.
The aero body righting of frog Rana rugulosus via hindleg swings
Authors: Wang Hong , Lin Feng , Mo Jixue , Xiao Jingcheng , Li Bing , Li Yao 
Published: July 2022

AbstractFrogs can keep an excellent aerial balance for landing and achieve consecutive jumps reliably. A safe landing requires an accurate body righting in the air. However, there is no systematic study on how the frogs adjust the aerial postures and body attitudes after jumping. The stretched long hindlegs swung quickly in the aerial phase, which revealed a clear relationship with the body attitudes. This study aimed to verify the function of frogs' hindlegs on aero body righting in the air. We captured the motions of both hindlegs and found the hindlegs adopted two movement modes, the bilateral parallel, and separated swings. The hindleg‐induced torques by the two movements were negatively correlated with the body's angular accelerations on pitch and roll, respectively. Moreover, an analytical model was derived based on the conservation of angular momentum and verified by the dynamic simulations. Thus, we confirmed that the hindlegs are the dominant mechanism in aerial pitch and roll controls. We anticipate our achievements to inspire the design of air‐righting tools.
Feasibility and Utility of the Venous Excess Ultrasound Score to Detect and Grade Central Venous Pressure Elevation in Critically Ill Children
Authors: Menéndez‐Suso Juan J. , Rodríguez‐Álvarez Diego , Sánchez‐Martín María 
Published: July 2022

ObjectivesThe Venous Excess Ultrasound (VExUS) score has been described as a useful tool to estimate the degree of venous congestion in adult patients. The present study aimed to analyze the feasibility and usefulness of the VExUS score to detect and grade central venous pressure (CVP) elevation in critically ill children.MethodsA cross‐sectional pilot study was conducted in a tertiary‐care pediatric intensive care unit between November 2020 and June 2021. All children in whom CVP was monitored, were enrolled. At the time of central venous catheter placement, CVP and VExUS score grade were determined, analyzing the inferior vena cava (IVC) diameter and the hepatic (HVD), portal (PVD), and intrarenal (IRVD) venous Doppler waveforms.ResultsA total of 33 children were studied (median age 12.2 [interquartile range (IQR) 4.1–100.6] months old; median weight 8.5 [IQR 5.6–35] kg; 20 [60.6%] males). The VExUS score was successfully obtained in 100% of the patients and its severity was strongly associated with the CVP levels (P < .001). Analyzing the VExUS score components separately, IVC dilation (P < .001) and severe HVD (P = .026), mild IRVD (P = .005), and severe IRVD (P = .025) patterns were associated with elevated CVP. After adjustment for confounding factors, IRVD pattern remained the only independent variable associated with elevated CVP.ConclusionsThe VExUS score appears to be a feasible and potentially useful bedside noninvasive monitoring tool for the detection and grading of CVP elevation in critically ill children. Among all its components, IRVD assessment seems most associated with high CVP in this population.
Autophagy in health and disease: From molecular mechanisms to therapeutic target
Authors: Lu Guang , Wang Yu , Shi Yin , Zhang Zhe , Huang Canhua , He Weifeng , Wang Chuang , Shen Han‐Ming 
Published: July 2022

AbstractMacroautophagy/autophagy is an evolutionally conserved catabolic process in which cytosolic contents, such as aggregated proteins, dysfunctional organelle, or invading pathogens, are sequestered by the double‐membrane structure termed autophagosome and delivered to lysosome for degradation. Over the past two decades, autophagy has been extensively studied, from the molecular mechanisms, biological functions, implications in various human diseases, to development of autophagy‐related therapeutics. This review will focus on the latest development of autophagy research, covering molecular mechanisms in control of autophagosome biogenesis and autophagosome–lysosome fusion, and the upstream regulatory pathways including the AMPK and MTORC1 pathways. We will also provide a systematic discussion on the implication of autophagy in various human diseases, including cancer, neurodegenerative disorders (Alzheimer disease, Parkinson disease, Huntington's disease, and Amyotrophic lateral sclerosis), metabolic diseases (obesity and diabetes), viral infection especially SARS‐Cov‐2 and COVID‐19, cardiovascular diseases (cardiac ischemia/reperfusion and cardiomyopathy), and aging. Finally, we will also summarize the development of pharmacological agents that have therapeutic potential for clinical applications via targeting the autophagy pathway. It is believed that decades of hard work on autophagy research is eventually to bring real and tangible benefits for improvement of human health and control of human diseases.
Modelling extreme rainfall events in Kigali city using generalized Pareto distribution
Authors: Singirankabo Edouard , Iyamuremye Emmanuel 
Published: July 2022

AbstractExtreme rain events have caused numerous issues and have had a significant impact on agriculture, human activities, ecology, infrastructure, and casualties. The theory of extreme values has been widely applied in extreme precipitation modelling and a variety of other fields. This paper employs the generalized Pareto distribution, which has been widely used to analyse extreme climates, in conjunction with the peak over thresholds approach to investigate exceedances. The occurrence of intense rainfall events in Kigali city causes severe damage to human properties, infrastructure damage, people injuries, loss of life, and other various harmful consequences. Early detection of extreme rainfall in Kigali aids in the development and implementation of strategies and measures to mitigate the negative effects of extreme rainfall before it occurs. The aim of this research is to estimate the frequency and magnitude of intense rainfall events in Kigali. The daily rainfall data from Kigali Airport station collected by Rwanda Meteorological Agency from 1990 to 2019 were applied. The results showed that as the return periods increased, so did the return levels, implying that the intensity and frequency of rainfall in Kigali will increase in the future. The model's goodness was tested, and the study suggests a model that has a non‐negative shape parameter (ξ) to be good. The study's findings are extremely important for understanding the occurrence of these events and also serve as a tool for decision‐making and the development of policies aimed at mitigating the effects of such events.