bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancement of Ionic Conductivity in NASICON‐Structured Li3(Zr,Ti)2(Si,Ge)2PO12: An Ab Initio Study
Authors: Wang Jiaqi , Huo Weirong , Peng Zhiwei , Tian Zongqing , Rehman Shafiq Ur , Mei Zongwei , Niu Yinghua , Lv Weiqiang 
Published: February 2025

AbstractThe development of solid electrolytes with high ionic conductivity is crucial for advancing solid lithium‐ion battery technology but is still a challenge. In this study, the ionic conductivity of NASICON‐structured materials Li3(Zr,Ti)2(Si,Ge)2PO12 are explored through ab initio molecular dynamics (AIMD) simulations. This investigation reveals the significant impact of isovalent substitution on the lithium‐ion diffusion pathways and the associated energy barriers. Elemental substitutions, such as replacing Zr with Ti, significantly reduce the Li site energy levels, enhance the polyhedral volume, and change the coordination structure from four‐coordinate to five‐coordinate, thereby facilitating lithium‐ion migration. Conversely, substituting Si with Ge reduces the diffusion channel size and increases fluctuation of Li migration potential surface, leading to less favorable ion transport conditions. Li3Ti2Si2PO12 exhibits a room temperature ionic conductivity of 5.79 × 10−2 Scm−1, 163% higher than that of the pristine Li3Zr2Si2PO12, with a reduced diffusion barrier of 0.16 eV. Additionally, these analyses reveal that the critical size for effective diffusion channels is vital: below this threshold, ion migration is suppressed; while above it, the channel size no longer limits migration.
Waste‐Derived Zn‐Based ASEI Layer for Enhanced Lithium Anodes in Lithium–Sulfur Batteries
Authors: Hajian Foroushani Mohsen , Maroufi Samane , Khayyam Nekouei Rasoul , Sahajwalla Veena 
Published: February 2025

AbstractThe formation of lithium (Li) dendrites on the anode during charge and discharge poses a significant challenge to the scalability of lithium‐metal batteries (LMBs). This study presents an innovative strategy leveraging waste‐derived Zn to create a hybrid in/ex situ artificial solid electrolyte interphase (ASEI) layer. The hybrid ASEI layer significantly improves the electrochemical performance of Li anodes compared to uncoated Li. In symmetrical cells, it demonstrates exceptional stability, maintaining a low overpotential of 9 mV over 400 cycles with a charge transfer resistance of 10.4 Ω, attributed to the high Li‐ion diffusivity provided by the ASEI layer. Unlike the bare Li, which develops a rough, thick, and uneven surface with cracks and dendrites after extended cycling, the ASEI‐coated anode exhibits a smooth and uniform surface. Furthermore, chemical analysis during cycling confirms the dynamic formation of beneficial LiZn within the ASEI layer. The performance of waste‐derived ASEI layer is examined in the real condition by pairing it with sulfur cathode. The cell delivers a remarkable specific discharge capacity of 1085 mAh g⁻¹ at 0.1C and retains 68% of its initial capacity after 300 cycles at 0.2C, outperforming bare Li, which retains only 54% under the same conditions.
Adenosine Monophosphate Improves Lipolysis in Obese Mice by Reducing DNA Methylation via ADORA2A Activation by Ecto‐5′‐Nucleotidase (CD73)
Authors: Cui Zhijuan , Feng Li , Rao Sujuan , Huang Zihao , Huang Shuangbo , Liu Liudan , Liao Yuan , Lan Zheng , Chen Qiling , Deng Jinping , Wang Leli , Yin Yulong , Tan Chengquan 
Published: February 2025

AbstractThe previous work discovers the potential of adenosine monophosphate (AMP) to alleviate obesity‐related metabolic diseases, but the underlying molecular mechanisms remain incompletely understood. Here, AMP is confirmed to enhance white fat decomposition and improve abnormal glucose and lipid metabolism in mice fed with a high‐fat (HF) diet. Mechanically, AMP is converted to adenosine (ADO) through ecto‐5′‐nucleotidase (CD73), and adenosine A2A receptor (ADORA2A) signaling activation is involved in the down‐regulation of methylation in white adipose tissue, thereby reducing the hormone‐sensitive lipase (HSL) methylation level and promoting HSL transcription and white fat decomposition. Moreover, the metabolic benefits of AMP are found to be partially eliminated in ADORA2A knockout mice, but re‐expression of ADORA2A can reproduce the AMP‐induced metabolic regulation in white fat. These findings reveal the mechanism that AMP, as the upstream of ADO, stimulates ADORA2A signaling and white fat DNA methylation to participate in the anti‐obesity effect.
Peptide Multifunctionalization via Modular Construction of Trans‐AB2C Porphyrin on Resin
Authors: Wu Yue , Wong Yuen‐Ting , Yeung Yik‐Hoi , Lam Pak‐Lun , Chau Ho‐Fai , Tam Wing‐Sze , Zhang Qian , Tai William C. S. , Wong Ka‐Leung 
Published: February 2025

AbstractPeptide multifunctionalization is a crucial technique to develop peptide‐based agents for various purposes. Porphyrin‐peptide conjugates are a class of popular multifunctional peptides renowned for their multifunctional and multimodal properties. However, the tedious synthetic works for porphyrin building blocks are involved in most previous studies. In this work, a modular solid‐phase synthetic approach is reported to construct trans‐AB2C porphyrin on peptide chains without presynthesized porphyrin building blocks. The products from this approach, which inherit both functionalities from the porphyrins and the modules employed for constructing porphyrins, show potential in biomedical and biomaterial applications. Furthermore, by extending this synthetic approach, the first example of “resin‐to‐resin” reaction is reported to link two peptides together along the construction of porphyrin motifs to give porphyrin‐peptide conjugates with two different peptide chains.
N4‐Acetylcytidine‐Mediated CD2BP2‐DT Drives YBX1 Phase Separation to Stabilize CDK1 and Promote Breast Cancer Progression
Authors: Wang Hongyu , Zhao Bozhi , Zhang Jiayu , Hu Qunyu , Zhou Linlin , Zhang Yinghui , Cai Yixin , Qu Yuansong , Jiang Tao , Zhang Dongwei 
Published: February 2025

AbstractLong noncoding RNAs (lncRNAs) play critical roles in the initiation and progression of breast cancer. However, the specific mechanisms and biological functions of lncRNAs in breast cancer remain incompletely understood. Bioinformatics analysis identifies a novel lncRNA, CD2BP2‐DT, that is overexpressed in breast cancer and correlates with adverse clinicopathological features and poor overall survival. Both in vivo and in vitro experiments demonstrate that CD2BP2‐DT promotes proliferation of breast cancer cells. Mechanistically, NAT10 mediates the N4‐acetylcytidine (ac4C) modification of CD2BP2‐DT, enhancing its RNA stability and expression. More importantly, CD2BP2‐DT enhances the stability of CDK1 mRNA by mediating YBX1 phase separation, thereby promoting the proliferation of breast cancer cells. In conclusion, the lncRNA CD2BP2‐DT is identified as a crucial driver of breast cancer cell proliferation through the YBX1/CDK1 axis, highlighting its potential as a promising biomarker and therapeutic target for breast cancer.
Ultrafast All‐Optical Switching and Active Sub‐Cycle Waveform Control via Time‐Variant Photodoping of Terahertz Metasurfaces
Authors: Jang Jeongmin , Rho Junsuk , Shin Hee Jun 
Published: February 2025

AbstractThe development of high‐speed and high‐performance optical switches has been a long‐standing issue in the field of photonics. This paper introduces a pioneering time‐resolved spectroscopy‐based approach for realizing photon‐induced ultrafast terahertz (THz) modulation within an electrical split‐ring resonator (SRR) via photoexcitation, rather than relaxation dynamics, in a silicon‐based indirect‐bandgap material. Two competitive effects (shorting of LC circuit and metallization of substrate) occur during photon‐induced THz modulation. The tradeoff between these two effects enables high‐speed optical switching via different time scales of the photoexcitation processes—THz‐optical cooperative effect and phonon‐assisted electron transition. THz‐optical cooperative photoexcitation, causing a shorting effect within the LC circuit, has been observed in the SRR gap, whose size typically exceeds that facilitating impact ionization (IMI). Notably, a remarkably short THz switching time of 1.3 ps has been achieved via only photoexcitation and with a high‐performance transmission intensity modulation depth of over 500%. In addition, active temporal waveform control down to a sub‐cycle pulse has been successfully demonstrated. The proposed approach suggests a new route for constructing high‐speed and efficient THz dynamic photonic devices with potential applications in temporal waveform control.
Tunable Hierarchically Porous Gadolinium‐Based Metal‐Organic Frameworks for Bacteria‐Targeting Magnetic Resonance Imaging and In Situ Anti‐Bacterial Therapy
Authors: Yu Youyi , Cui Tianming , Liu Chang , Yang Weitao , Zhang Bingbo 
Published: February 2025

AbstractCurrently, there are no non‐invasive tools to accurately diagnose deep surgical site bacterial infections before they cause significant anatomical damage in the clinic. An urgent need exists for bacteria‐targeting bifunctional probes for the detection of deep bacterial infections and precise in situ treatment. Herein, the bacteria‐targeting 1‐borono‐3,5‐benzenedicarboxylic acid (BBDC) ligand and paramagnetic Gd3 + into one single metal‐organic frameworks (MOFs) are integrated, synergistically realizing bacteria‐specific magnetic resonance imaging (MRI) diagnosis and MRI‐guided antibacterial treatment. Molecular simulations and nitrogen adsorption‐desorption experiments demonstrate that a hierarchical porous structure can be constructed by tuning the Gd3 + /BBDC ratio, which endows the Gd‐BBDC1.25 MOFs with an impressive longitudinal proton relaxivity of 15.81 mM−1 s−1. In particular, the bacteria‐targeting boronic acid group in BBDC remained intact during the MOF synthesis, ensuring that Gd‐BBDC1.25 MOFs have a unique combination of high sensitivity and specificity for bacteria. Through an in situ reduction reaction, silver nanoparticles （Ag NPs）‐modified Gd‐BBDC1.25 MOFs to form Ag@Gd‐BBDC1.25, an interfacial Schottky heterojunction nanozyme, which enhances their peroxidase (POD)‐catalyze activity. Furthermore, it is demonstrated that the bacteria‐targeting Ag@Gd‐BBDC1.25 bifunctional probe can image as few as 105 colony‐forming units (cfu) in vivo and effectively eradicate the bacteria in situ.
Development of Self‐Aligned Top‐Gate Transistor Arrays on Wafer‐Scale Two‐Dimensional Semiconductor
Authors: Zhu Yuxuan , Zhang Jinshu , Xie Hui , Xia Yin , Dong Xiangqi , Gou Saifei , Zhang Zhejia , He Xinliu , Chen Haojie , Ao Mingrui , Sun Qicheng , Hu Yan , Tian Yuchen , Shang Jieya , Song Yufei , Wang Jiahao , Wang Sen , Yue Xiaofei , Cong Chunxiao , Zhou Lihui , Dai Sheng , Xu Zihan , Wan Jing , Qiu Haibing , Wang Yin , Tan Xiaojun , Bao Wenzhong 
Published: February 2025

AbstractTwo‐dimensional semiconductor materials (2DSM) effectively mitigate the short‐channel effect due to their atomic thickness, offering significant advantages over traditional silicon‐based materials, particularly in short channel length. In manufacturing 2DSM top‐gate field‐effect transistors (TG‐FETs), simultaneous miniaturization of the gate and channel can only be achieved through a self‐alignment process, enabling high‐density integration of short‐channel FETs. However, current self‐aligned FETs based on 2DSM face challenges in attaining wafer‐scale integration due to manufacturing process limitations. This work has successfully developed high‐performance and wafer‐scale TG‐FET arrays using a self‐aligned method that integrates the processes of dry etching, wet selective etching, and post‐device optimization. The miniaturization is demonstrated by fabricating TG‐FETs with a channel length of 200 nm, achieving an impressive on‐state current density of 465.5 µA µm−1 and a high on‐off current ratio of 108. Furthermore, we constructed the inverters and logic modules based on self‐aligned FETs, showcasing the process's compatibility for future integration.
Ultrabroadband Directional Tunable Thermal Emission Control Based on Vanadium Dioxide Photonic Structures
Authors: Chen Qixiang , Li Chengcong , Huang Xuemei , Lu Yuehui , Xu Hua , An Yang , Li Longnan , Li Wei , Yin Xiaobo , Cao Xun , Zhao Dongliang 
Published: February 2025

AbstractThe manipulation of thermal radiation amplitude or direction over a broadband spectrum is a fundamental capability, demonstrating significant potential in thermal management and infrared information encryption. However, existing approaches cannot control both aspects simultaneously. In this study, an ultrabroadband directional tunable thermal emitter (UDTTE) utilizing the metal‐insulator transition properties of vanadium dioxide photonic structure and the Brewster effect is proposed. Before the phase transition, the UDTTE exhibits an average emissivity as low as 0.07 across the 3–20 µm band and the entire range of angles. After the phase transition, the UDTTE maintains a low emissivity of 0.33 for incident angles below 73° but displays a high emissivity of 0.78 in the 73°–83° range. This designed experiments in information encryption demonstrate that the UDTTE can synergistically utilize temperature, viewing angle, and polarization to achieve multi‐level encryption of IR information. This strategy further enhances the capability to manipulate thermal radiation and holds promise for advancing technologies in information security, IR camouflage, and thermal management.
Insertion Type Li3VO4 Lithiophilic Sites Boosting Dendrite‐Free Lithium Deposition in Trapping‐and‐leveling Model
Authors: Sun Bing , Kuang Lingling , He Meichun , Zhang Qin , Guan Yunfeng , Zhang Chengzhi , Zhang Dongmei , Pei Cunyuan , Li Pengju , Ni Shibing 
Published: February 2025

AbstractLithium (Li) metal batteries offer high energy densities but suffer from uncontrolled lithium deposition, causing serious dendrite growth and volume fluctuation. Tailorable Li nucleation and uniform early‐stage plating are essential for homogenous Li deposition. Herein, insertion type Li3VO4 is first demonstrated as efficient lithiophilic sites trapping Li+ ions for homogenous nucleation. By homogenizing the distribution of electric field and ions flux via an ingenious architecture design with Li3VO4 nanodots grown on the carbon fibers (LVO@CNFs), leveling Li metal deposition after nucleation is also realized. These, together, result in smooth and dendrite‐free Li deposition on the LVO@CNFs via a trapping‐and‐leveling model, giving rise to unprecedented performance (highly stable Li plating/stripping exceeding 2500 h at 2 mA cm−2 under 3 mA h cm−2 capacity, high‐capacity retention of 82.5% over 500 cycles in a Li@LVO@CNFs//LiFePO4 battery). The successful design of Li metal deposition host via insertion‐type Li3VO4 may pave a new way for long lifespan Li metal batteries.
Centering Latinx immigrant knowledge for wellbeing, liberation, and justice in community‐university research partnerships
Authors: Echeverri Herrera Susana , Ruiz‐Negrón Bianca , Lemus Alejandra , Guzmán Cirila Estela Vasquez , Hess Julia Meredith , Ramírez Janet , Ramírez Sonia , Casas Norma , Galvis Margarita , Aguirre Ivonne , Goodkind Jessica R. 
Published: February 2025

AbstractStructural inequities impacting immigrant health in the United States were intensified during two recent time periods—the anti‐immigrant socio‐political context of 2017–2021 and the COVID‐19 pandemic beginning in 2020. Our community‐university research team adapted and implemented a community‐based mental health intervention with Latinx immigrants during these periods, which allowed us to reflect on the role of our community‐based participatory research (CBPR) partnership in addressing the disparate impacts of these events on Latinx immigrants. We documented the factors and processes that enabled our partnership to navigate crises, address immediate needs, and promote long‐term social change. We analyzed focus groups with community‐based organization staff, research team meetings, retreat notes, and interviews with Latinx immigrants. Exacerbated challenges included fear, uncertainty, limited resources, and restricted mobility and isolation. By prioritizing immigrant individual, community, and organizational knowledge and epistemologies, our team built upon immigrants' experiences of survival and resistance in the face of ongoing exclusion to navigate the difficulties of both periods. Instead of developing reactive processes, our partnership centered on immigrants' existing strategies, ensuring responses were rapid, effective, and aligned with community needs. These findings highlight that immigrant communities survive continual “crises” and engage in ongoing resistance and survival strategies that can provide the basis for effective CBPR and other social change efforts.
Hearing the voices of Ukrainian refugee women in Italy to enhance empowerment interventions
Authors: Guidi Elisa , Tosti Anna Enrica , Meringolo Patrizia , Hatalskaya Halina , Chiodini Moira 
Published: February 2025

AbstractThe 2022 Russian invasion displaced millions of Ukrainians, many of whom sought refuge in Italy. War refugees face heightened mental‐health risks but can also activate resilience and empowerment. This study employed the Transtheoretical Model of Empowerment and Resilience (Brodsky & Cattaneo, 2013) to explore resilience and empowerment processes implemented by Ukrainian refugee women in Italy to cope with war‐related challenges and living in a new country. Twenty Ukrainian refugee women completed questionnaires and participated in semi‐structured interviews. Results indicated perceived psychological distress following traumatic war experiences. Utilizing individual and shared resources, respondents enacted resilience processes stemming from the context of risk in their home country and the receiving country but not empowerment actions. However, some mentioned empowerment goals, such as changes in the formal support system for refugees and creating a network of Ukrainian refugees for mutual support. Results highlighted how some participants held individual characteristics of relative privilege, which could be crucial for transitioning from resilience to empowerment. The study suggests that facilitating this transition may require tailored interventions for the specific needs of Ukrainian refugee women and community‐based interventions for promoting access to shared opportunities with the local community and other migrants.
Longitudinal Metabolomics in Amyotrophic Lateral Sclerosis Implicates Impaired Lipid Metabolism
Authors: Guo Kai , Savelieff Masha G. , Jang Dae‐Gyu , Teener Samuel J. , Zhao Lili , Hur Junguk , Goutman Stephen A. , Feldman Eva L. 
Published: February 2025

ObjectiveAmyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by altered metabolome and energy homeostasis, manifesting with body mass index changes and hypermetabolism—both prognostic of disease progression and survival. The cross‐sectional ALS metabolome has been characterized, but longitudinal correlations to functional decline are lacking.MethodsWe longitudinally evaluated metabolomes from ALS plasma and terminal postmortem spinal cord and brain motor cortex tissue. We constructed 3 plasma models. A linear mixed effects model correlated all metabolite levels across all timepoints to their corresponding functional scores. An interaction model predicted a longitudinal change in function from baseline metabolites, whereas a progression model identified metabolites linked to a 20% or 50% drop in function. In postmortem samples, differential metabolites in onset versus second spinal cord segments served as a surrogate of disease progression. Mendelian randomization assessed potential causality from metabolites.ResultsIn plasma, all models primarily selected lipid metabolites and sub‐pathways, in addition to amino acids, xenobiotics, and various less frequently selected pathways. Among lipids, fatty acids and sphingomyelins were predominant, along with plasmalogens, phosphatidylcholines, and lysophospholipids. Sex interaction findings were nominal. In the spinal cord, sphingomyelin and long‐chain saturated and monounsaturated fatty acids were more abundant in the onset segment tissue, whereas phosphatidylcholines and phosphatidylethanolamines were less abundant. Mendelian randomization suggested that impaired carnitine and short chain acylcarnitine metabolism may be genetically determined in ALS, along with various antioxidant derivatives.InterpretationOur findings suggest metabolomic changes primarily involving different lipid classes and carnitine metabolism may underscore ALS severity and progression. ANN NEUROL 2025
Auf dem Weg zur oberflächenverstärkten homogenen Katalyse: Maßgeschneiderte Anreicherung von Metallkomplexen an der Oberfläche von ionischen Flüssigkeiten
Authors: Hemmeter Daniel , Haumann Marco , Williams Federico J. , Koller Thomas M. , Wasserscheid Peter , Meyer Karsten , Maier Florian , Steinrück Hans‐Peter 
Published: February 2025

AbstractIn der homogenen Katalyse geht man üblicherweise davon aus, dass sich die Konzentrationen der Übergangsmetallkomplexe an der Gas‐Flüssig‐Grenzfläche und im Volumen der Lösung nicht unterscheiden. Tatsächlich zeigen aber umfangreiche Untersuchungen an gelösten Metallkomplexen in ionischen Flüssigkeiten (Englisch: Ionic Liquids, ILs) ausgeprägte Oberflächenanreicherungs‐ und Segregationseffekte, die auch für praktische Anwendungen von großer Bedeutung sein können. Diese Untersuchungen basieren auf Methoden der Oberflächenforschung, die aufgrund der vernachlässigbaren IL‐Dampfdrücke unter wohldefinierten Vakuumbedingungen anwendbar sind. Dieser Übersichtsartikel bietet einen Überblick über die jüngsten Fortschritte bei der Steuerung der Grenzflächenzusammensetzung von katalytischen Systemen auf der Basis ionischer Flüssigkeiten. Ein besonderer Schwerpunkt liegt auf der gezielten Oberflächenanreicherung. Insbesondere werden eine Vielzahl von Parametern vorgestellt, welche die lokale Komplexkonzentration an der Oberfläche beeinflussen wie etwa die Wahl der Liganden, die Konzentration im Volumen, die Temperatur und die Natur des IL‐Lösungsmittels. Als experimentelle Methoden wurden vor allem winkelaufgelöste Röntgenphotoelektronenspektroskopie (Englisch: Angle‐Resolved X‐Ray‐Photoelectron Spectroscopy, ARXPS) und Oberflächenspannungsmessungen mit der Methode des hängenden Tropfens (Englisch: Pendant Drop Method) unter ultrareinen Vakuumbedingungen eingesetzt. Die hier zusammengefassten Ergebnisse bilden die Grundlage für die Weiterentwicklung von maßgeschneiderten katalytischen Anwendungen mit großer innerer Oberfläche, z.B. in der Katalyse mit geträgerten ionischen Flüssigphasen (Englisch: Supported Ionic Liquid Phase, SILP); bei solchen Systemen hat das Design der Grenzfläche einen erheblichen Anteil an der katalytischen Effizienz.
Fabrication of Lightweight Polyimide Aerogels With Excellent Mechanical and Thermal Properties by Changing the Dianhydride Structures
Authors: Shen Lu , Sun Binbin , Ni Long , Liao Xiaoting , Luo Yinfu , Zhou Shengtai , Zou Huawei 
Published: February 2025

ABSTRACTNowadays, it becomes imperative to develop polyimide (PI) aerogels with excellent thermal insulation and mechanical performance to suit the demanding needs in high‐tech sectors such as aerospace, electronics and fire protection among others. Herein, a series of PI aerogels with different dianhydride structures were prepared by sol–gel method, with 2,2′‐dimethylbenzidine (DMBZ) being used as the diamine. The microstructure, mechanical properties, thermal stability, and thermal insulation properties of PI aerogels were regulated by changing the dianhydride structure. The compressive strength of PI aerogels at 10% strain was in the range of 0.04–1.60 MPa, and PIPMDA‐DMBZ aerogel exhibited the best compressive strength among the studied systems. In addition, PIBPDA‐DMBZ aerogel had an initial degradation temperature up to 510°C and thermal conductivity as low as 0.032 W/(m⋅K), demonstrating excellent thermal stability and insulation properties that can withstand harsh conditions.