bluuebunny/crossref_metadata_2025_split huggingface dataset:
A long-term obesogenic high-fat diet in mice partially dampens the anti-frailty benefits of late-life intermittent fasting
Authors: Henderson Yoko O. , Bithi Nazmin , Yang Jie , Link Christopher , Zhang Aili , Baron Benjamin , Maina Eran , Hine Christopher 
Published: October 2022

AbstractThe global obesity pandemic coupled with ever-growing life expectancies equates to hundreds of millions of individuals with potentially longer but not healthier lives. Aging is one of the risk factors for numerous maladies such as metabolic disorder and frailty, which are exacerbated under obesity. Thus, therapeutic approaches that address obesity to ultimately improve affected individuals’ quality of life and extend their lifespan are needed. We previously reported that the every other day (EOD) fasting initiated late-life improved metabolic, musculoskeletal, and cognitive endpoints in standard rodent diet-fed mice. In the present study, using the same dietary intervention methodology, we tested if 2.5 months of EOD fasting could improve metabolic, physiological, and cognitive endpoints in mice after an 18 month obesogenic high-fat diet (HFD). The positive effects of EOD fasting were generally consistent across the endpoints; EOD fasting decreased total body mass, maintained more %lean mass, improved glucose tolerance and utilization, and improved neuromuscular function. In contrast to our previous study, grip strength, hippocampal-dependent memory, and renal hydrogen sulfide (H2S) production were not improved by the HFD EOD fasting. Thus, efficacy for late-life initiated intermittent fasting to improve specific frailty markers may be partially dependent on nutritional compositions of the diet.
Promising WC-30WB-10Co Cemented Carbide Coating with Improved Density and Hardness Deposited by High Velocity Oxy-Fuel Spraying: Microstructure and Mechanical Properties
Authors: Liu Baogang , Xiao Fen , Zhu Haifan , Tang Min 
Published: October 2022

AbstractWC-Co coatings sprayed by HVOF attracted much attentions, benefiting from the satisfactory wear resistance and high bonding strength to the steel substrates. Nevertheless, high density of conventional coatings required excessive Co binder, which decreased the hardness and operation life. Based on this, a strengthened WC-30WB-10Co coating was developed with both high density and improved hardness, using high-qualified thermal sprayed composite powders. Comparison between the phase composition, microstructure, interfacial bonding strength and properties of the newly developed coatings and WC-12Co conventional coatings was clarified in detail. Compared to WC-12Co powders, spherical WC-30WB-10Co powders showed higher apparent density and flowability, due to the in situ formed CoWB and CoW2B2 phases during the accelerated metallurgy reaction. Oxidation and decarburization were confirmed during HVOF spraying with the formation of W2C, Co3W3C and Co6W6C phases in both coatings. Attracting WC-30WB-10Co coating with microhardness of 1639HV0.3 and relative density of 99.44% was achieved, higher than those of 1222 HV0.3 and 99.27% of WC-12Co. This was attributed to the formation of the ternary compounds and the consumption of the ductile Co binder in the WC-30WB-10Co coatings. The hard alloy coatings are expected to be well applied in aggressive wear and corrosion environments due to the high hardness and low metal phase content.
A retrospective review of a large series of groin hernia patients operated with robotically assisted laparoscopic technique (R-TAPP)
Authors: Bondi Johan , Botnen Hans Gunnar , Baekkelund Oliver , Groven Sigrid 
Published: October 2022

AbstractWe have reviewed the patient outcome and the feasibility of robotically assisted inguinal hernia repair (R-TAPP) from the first 4-years period after its introduction in our department in a Scandinavian Public Health hospital. A total of 226 hernia repairs were performed in 195 patients (31 bilateral hernias). 160 patients had primary hernias, whereas 35 had recurrent hernias. Of the recurrent hernias, three had recurred twice. The majority of the hernias were in the right groin (53.3%) and the lateral location was the most common (65.0%). The hernia was scrotal in 29 cases. The mean operation time was significantly reduced throughout the observation period for our cohort, i.e. from 81 to 57 min (p < 0.001). The operation time was 27 min faster (mean value) in unilateral vs bilateral hernias and 19 min faster (mean value) in primary vs residual hernias. There were no statistically significant differences in operation time between lateral and medial hernias, and no differences in operation time between the obese and normal-weight cases. We experienced four severe per-operative complications (4/226; 1.8%): two cases of abdominal wall bleeding subsequently undergoing intravascular coiling, one perforation of the urinary bladder and one perforation of small bowel that were both closed by direct suture intraoperatively. There were no conversions to laparoscopy or open procedure. One hernia recurred during the observation period. Our findings suggest that the R-TAPP procedure in a Scandinavian Public Health hospital’s surgical department is both safe and feasible.
Activated Carbon from Sugarcane Bagasse Pyrolysis for Heavy Metals Adsorption
Authors: Kakom S. M. , Abdelmonem N. M. , Ismail I. M. , Refaat A. A. 
Published: October 2022

AbstractSugarcane bagasse is an agro-industrial waste available in enormous quantities in Egypt. It is rich of organic carbon which makes it a potential feedstock for activated carbon production. This study provides an optimized pyrolysis method for activated carbon production from Sugarcane bagasse. Sugarcane bagasse samples impregnated with sulfuric acid, for 24 h, and carbonized at 500 °C, for two hours, yielded the best activated carbon with a surface area of 431.375 m2/g. The best impregnation ratio was 2.5:1 (sulfuric acid/bagasse). The prepared activated carbon was used for adsorbing heavy metals (Pb, Cd, Mn, Cu, Cr) from Nile Tilapia reused frying oil. It could adsorb 80% of the heavy metals and particularly removed the Cd. The characteristics of the prepared activated carbon are comparable to those recommended for the commercial activated carbon. The production cost of the activated carbon using this method is about 707 $ which is cheaper than the commercial activated carbon by about 40%.
Taxonomic assessment of deep-sea decapod crustaceans collected from polymetallic nodule fields of the East Pacific Ocean using an integrative approach
Authors: Christodoulou Magdalini , De Grave Sammy , Vink Αnnemiek , Martinez Arbizu Pedro 
Published: October 2022

AbstractDeep-sea decapod crustaceans (Crustacea: Decapoda) collected during nine research cruises to the Clarion-Clipperton Zone (CCZ) in the NE Pacific Ocean and the Peru Basin in the SE Pacific Ocean were studied comprehensively using an integrative taxonomic approach. The abyssal seafloors of both areas are rich in economically interesting polymetallic nodules. All specimens were morphologically identified and genetically analysed using a fragment of the mitochondrial cytochrome c oxidase subunit I (COI). Eight species were collected, comprising three anomurans, three carideans, one dendrobranchiate, and one brachyuran, from water depths ranging between 4089 and 4511 m. COI sequences for representatives of the generaParapagurusSmith, 1879,EthusinaSI Smith, 1884, andBathystylodactylusHanamura & Takeda, 1996 are provided for the first time. The molecular barcodes of the species provided herein will be valuable for the full taxonomic assignment of sequences produced in future metabarcoding and eDNA monitoring work. The new records extend the geographical distributional ranges or fill geographical gaps of the species reported, although none of the species is endemic to polymetallic nodule areas. This study is part of a taxonomic series aiming to describe the biodiversity of areas targeted for future deep-sea mining.
Acute effects of long-lasting stretching and strength training on maximal strength and flexibility in the calf muscle
Authors: Warneke Konstantin , Wohlann Tim , Lohmann Lars H. , Wirth Klaus , Schiemann Stephan 
Published: October 2022

AbstractThe so-called “stretch-induced force deficit” is known from a large amount of research. There are many theories trying to explain the stretch-induced force deficit and increases in the range of motion (ROM) which all offer a stretch training-specific explanation. However, when performing a commonly used strength training session, a reduced maximum strength (MSt) capacity can be assumed as well. Based on this, the aim of the study is to investigate the tension-induced force deficit due to a suprathreshold strength or stretching training stimulus. Therefore, 71 participants (age: 24.1 ± 4.2 years, height: 176.3 ± 5.7 cm, weight: 74.1 ± 7.5 kg) were divided into three groups: static stretching group (SST), strength training group (STR), and control group (CG). To investigate possible mechanical tension-induced force deficits, SST performed a long-lasting static stretching intervention for 1 h using an orthosis, while STR executed a common strength training intervention (5 × 12 repetition) for the plantar flexors. The results show a significant reduction of measured MSt as well as increased ROM for both SST and STR following the interventions. Consequently, we found similar acute effects of stretching and strength training regarding MSt and flexibility. We conclude that the decreased MSt capacities can possibly be attributed to mechanical tension-induced damage of the muscle that is not linked to a specific training method. The improvements in flexibility found in both intervention groups might be attributed to warm up effects when inducing high mechanical tension to large ankle joint angles.
Bio-based hybrid cabin door of ultralight helicopter with variable-axis fiber design
Authors: Svidler Rostislav , Rinberg R. 
Published: October 2022

AbstractThis paper presents the development of an integrated technology concept for the production of semi-structural fiber composite aerospace components with a bio-based hybrid laminate structure. In this context, the high lightweight potential of a variable-axial hybrid fiber-reinforced laminates compared to a multiaxial laminate design is of particular importance. As a demonstrator, a double-shell cabin door based on the cabin door of the ultra-light helicopter CoAx 2D of EDM Aerotec GmbH was redesigned in hybrid bio-based mixed composite construction using selected finite-element method (FEM) simulation and optimization tools, manufactured and characterized. The obtained results illustrate that compared to the reference carbon fiber-reinforced polymer (CFRP) component, the developed bio-based hybrid composite with local tailored fiber placement (TFP) reinforcement has a 30% biomass content, exhibits comparable mechanical properties and significantly contributes to increase energy and resource efficiency significantly.
Outpatient inguinal hernia repair in Spain: a population-based study of 1,163,039 patients—clinical and socioeconomic factors associated with the choice of day surgery
Authors: Guillaumes Salvador , Hidalgo Nils Jimmy , Bachero Irene , Juvany Montserrat 
Published: October 2022

AbstractReducing inpatient admissions and health care costs is a central aspiration of worldwide health systems. This study aimed to evaluate trends in outpatient surgery in inguinal hernia repair (IHR) and factors related to the outpatient setting in Spain. A retrospective cohort study (Record-Strobe compliant) of 1,163,039 patients who underwent IHR from January 2004 to December 2019 was conducted. Data were extracted from the public clinical administrative database CMBD (“Conjunto Mínimo Básico de Datos”). The primary outcome was the outpatient surgery rate. Univariate and multivariable analyses were performed to identify clinical and socioeconomic factors related to the outpatient setting. The overall proportion of outpatient repairs was 30.7% in 2004 and 54.2% in 2019 (p < 0.001). Treatment in a public hospital was the most remarkable factor associated with the likelihood of receiving an outpatient procedure (OR 3.408; p < 0.001). There were also significant differences favouring outpatient procedures for patients with public insurance (OR 2.351; p < 0.001), unilateral hernia (OR 2.903; p < 0.001), primary hernia (OR 1.937; p < 0.0005), age < 65 years (OR 1.747; p < 0.001) and open surgery (OR 1.610; p < 0.001). Only 9% of patients who pay for their intervention privately or 15% of those covered by private insurance were treated as outpatients. Spain has significantly increased the rate of outpatient IHR over the last 16 years. However, the figures obtained still leave a significant margin for improvement. Important questions about the acceptance of outpatient settings remain to be answered.
Graphical Abstract

Outpatient inguinal hernia repair in Spain. A population-based study of 1,163,039 patients: clinical and socioeconomic factors associated with the choice of day surgery.
Versorgung und Versorgungskonzepte in der Kinder- und Jugendpsychiatrie
Authors: Thun-Hohenstein Leonhard 
Published: October 2022

Zusammenfassung
Hintergrund
Die Situation der Kinder- und Jugendpsychiatrischen Versorgung hat sich seit 2007, seit der Schaffung des Sonderfaches KJP+P, sukzessive verbessert. Die Arbeitsgruppe Versorgung der ÖGKJP gibt in diesem Heft einen Überblick über die KJP-Versorgungssituation in Österreich. In dieser Einführung geht es um die Darstellung der rechtlichen Vorgaben und deren Umsetzung. Es bestehen nach wie vor massive Defizite der KJP-Versorgung.
Im Österreichischen Strukturplan Gesundheit (ÖSG) ist das momentan gültige Versorgungskonzept festgeschrieben und umfasst die ambulante, teilstationäre und stationäre Versorgung. Für die ambulante und stationäre Versorgung existieren Messzahlen, für die teilstationäre Versorgung nicht.
Das Fachgebiet KJP hat verschiedene Besonderheiten: die Multimodalität, die Multiprofessionalität, die Altersgruppen der Betroffenen, pro Alter unterschiedliche und unterschiedlich ausgeprägte Erkrankungen, die Beschränkung auf eine bestimmte Altersgruppe (< 19 Jahre) und – das verbindet es mit dem Fach Psychiatrie – eine hohe Prävalenz der Erkrankungen sowie die Integration der Psychotherapeutischen Medizin in den Facharzt.

Schlussfolgerungen
Die aus diesen Besonderheiten sich ergebenden Konsequenzen – altersdifferenzierte Angebote, fachübergreifende Kooperation etc. – haben bisher keinen Eingang in die strukturellen und finanziellen Berechnungen gefunden. Anhand der den Begriff Versorgung beschreibenden Begriffe: „care“, „provision“ und „supply“ wird ein Modell vorgestellt, das bei der Planung von Gesundheitsmaßnahmen in diesem Bereich als Denkansatz herangezogen werden könnte. Da psychisch kranke Kinder und Jugendliche sich in allen Teilen der Gesellschaft finden, wird die Einrichtung einer zentral verantwortlichen und ressortübergreifenden Stelle für Mental Health gefordert.
Gambling in Sub-Saharan Africa: Traditional Forms and Emerging Technologies
Authors: Bitanihirwe Byron K. Y. , Adebisi Tunde , Bunn Christopher , Ssewanyana Derrick , Darby Paul , Kitchin Paul 
Published: October 2022

AbstractPurpose of ReviewThe gambling industry in Africa has seen substantial growth and evolution over recent years with a growing body of literature describing these shifts. Here, we provide a narrative synthesis of the extant literature on the origins, trends and consequences of the expansion and intensification of the commercial gambling industry in sub-Saharan Africa with a reference for future research on gambling as a growing public health concern.Recent FindingsThe historical shift and permeation of gambling in sub-Saharan Africa is diverse with evidence of certain countries following a neo-colonial logic. Advances in technology have made gambling more accessible and created new markets in Africa. A key motive driving gambling on the continent is a lack of stable employment. While the intensification and growth of Africa’s gambling industry has brought economic benefits to some African investors and individuals, this has been accompanied by a range of gambling harms. Legislation and policies designed to better regulate the gambling industry and redress these harms are needed. In this context, a small number of services and campaigns designed to mitigate gambling harms demonstrate promise, but more research is needed in this area.SummaryThe gambling industry in sub-Saharan Africa has undergone a dramatic transformation. While it is true that the growth of the African gambling industry has provided an additional revenue stream to governments, it is also necessary to acknowledge the concurrent rise in gambling addiction and the health-related and social harms that it elicits. As such, designing effective regulatory measures and policy interventions that can reduce the public health burden of gambling harms is vital. However, these interventions need to take in to account the significance of cultural differences that exist among countries on the continent.
Role of vitamin D supplementation in the management of musculoskeletal diseases: update from an European Society of Clinical and Economical Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group
Authors: Chevalley Thierry , Brandi Maria Luisa , Cashman Kevin D. , Cavalier Etienne , Harvey Nicholas C. , Maggi Stefania , Cooper Cyrus , Al-Daghri Nasser , Bock Oliver , Bruyère Olivier , Rosa Mario Miguel , Cortet Bernard , Cruz-Jentoft Alfonso J. , Cherubini Antonio , Dawson-Hughes Bess , Fielding Roger , Fuggle Nicholas , Halbout Philippe , Kanis John A. , Kaufman Jean-Marc , Lamy Olivier , Laslop Andrea , Yerro Maria Concepción Prieto , Radermecker Régis , Thiyagarajan Jotheeswaran Amuthavalli , Thomas Thierry , Veronese Nicola , de Wit Marten , Reginster Jean-Yves , Rizzoli René 
Published: October 2022

AbstractVitamin D is a key component for optimal growth and for calcium–phosphate homeostasis. Skin photosynthesis is the main source of vitamin D. Limited sun exposure and insufficient dietary vitamin D supply justify vitamin D supplementation in certain age groups. In older adults, recommended doses for vitamin D supplementation vary between 200 and 2000 IU/day, to achieve a goal of circulating 25-hydroxyvitamin D (calcifediol) of at least 50 nmol/L. The target level depends on the population being supplemented, the assessed system, and the outcome. Several recent large randomized trials with oral vitamin D regimens varying between 2000 and 100,000 IU/month and mostly conducted in vitamin D-replete and healthy individuals have failed to detect any efficacy of these approaches for the prevention of fracture and falls. Considering the well-recognized major musculoskeletal disorders associated with severe vitamin D deficiency and taking into account a possible biphasic effects of vitamin D on fracture and fall risks, an European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) working group convened, carefully reviewed, and analyzed the meta-analyses of randomized controlled trials on the effects of vitamin D on fracture risk, falls or osteoarthritis, and came to the conclusion that 1000 IU daily should be recommended in patients at increased risk of vitamin D deficiency. The group also addressed the identification of patients possibly benefitting from a vitamin D loading dose to achieve early 25-hydroxyvitamin D therapeutic level or from calcifediol administration.
Derivatives of L-series of weakly holomorphic cusp forms
Authors: Diamantis Nikolaos , Strömberg Fredrik 
Published: October 2022

AbstractBased on the theory ofL-series associated with weakly holomorphic modular forms in Diamantis et al. (L-series of harmonic Maass forms and a summation formula for harmonic lifts.arXiv:2107.12366), we derive explicit formulas for central values of derivatives ofL-series as integrals with limits inside the upper half-plane. This has computational advantages, already in the case of classical holomorphic cusp forms and, in the last section, we discuss computational aspects and explicit examples.
Iodine Promoted Ultralow Zn Nucleation Overpotential and Zn-Rich Cathode for Low-Cost, Fast-Production and High-Energy Density Anode-Free Zn-Iodine Batteries
Authors: Zhang Yixiang , Wang Lequan , Li Qingyun , Hu Bo , Kang Junming , Meng Yuhuan , Zhao Zedong , Lu Hongbin 
Published: October 2022

AbstractThe anode-free design is a promising strategy to increase the energy density of aqueous Zn metal batteries (AZMBs). However, the scarcity of Zn-rich cathodes and the rapid loss of limited Zn greatly hinder their commercial applications. To address these issues, a novel anode-free Zn-iodine battery (AFZIB) was designed via a simple, low-cost and scalable approach. Iodine plays bifunctional roles in improving the AFZIB overall performance: enabling high-performance Zn-rich cathode and modulating Zn deposition behavior. On the cathode side, the ZnI2 serves as Zn-rich cathode material. The graphene/polyvinyl pyrrolidone heterostructure was employed as an efficient host for ZnI2 to enhance electron conductivity and suppress the shuttle effect of iodine species. On the anode side, trace I3− additive in the electrolyte creates surface reconstruction on the commercial Cu foil. The in situ formed zincophilic Cu nanocluster allows ultralow-overpotential and uniform Zn deposition and superior reversibility (average coulombic efficiency > 99.91% over 7,000 cycles). Based on such a configuration, AFZIB exhibits significantly increased energy density (162 Wh kg−1) and durable cycle stability (63.8% capacity retention after 200 cycles) under practical application conditions. Considering the low cost and simple preparation methods of the electrode materials, this work paves the way for the practical application of AZMBs.
From quantitative SBML models to Boolean networks
Authors: Vaginay Athénaïs , Boukhobza Taha , Smaïl-Tabbone Malika 
Published: October 2022

AbstractModelling complex biological systems is necessary for their study and understanding. Biomodels is a repository of peer-reviewed models represented in the Systems Biology Markup Language (SBML). Most of these models are quantitative, but in some cases, qualitative models—such as Boolean networks (BNs)—are better suited. This paper focuses on the automatic transformation of quantitative SBML models to Boolean networks. We propose SBML2BN, a pipeline dedicated to this task. Our approach takes advantage of several SBML elements (reactions, rules, events) as well as a numerical simulation of the concentration of the species over time to constrain both the structure and the dynamics of the Boolean networks to synthesise. Finding all the BNs complying with the given structure and dynamics was formalised as an optimisation problem solved in the answer-set programming framework. We run SBML2BN on more than 200 quantitative SBML models, and we provide evidence that one can automatically construct Boolean networks which are compatible with the structure and the dynamics of an SBML model. In case the SBML model includes rules or events, we also show how the evaluation criteria are impacted when taking these elements into account.