bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case report of incidentally elevated maternal serum alkaline phosphatase managed in a poor resource setting
Authors: Naik Salonee Milind , Naik Pornima Rajkumar 
Published: August 2022

The normal serum concentration of alkaline phosphatase (ALP) in adults ranges from 47 to 147 IU/l. Alkaline phosphatase is known to be produced by syncytiotrophoblasts in the placenta during pregnancy. Its levels are normally increased in pregnant women and levels of up to twice the upper limit can be considered normal. There have been case reports pointing out that an abnormal rise in serum ALP levels could be a marker for placental insufficiency preterm delivery. Here we report a case with delivery of a normal infant and no placental pathology at term. There are very few reports of extreme elevations of ALP in a pregnancy without any co-morbidities and delivery of normal infant with a subsequent decline to normal after delivery. We present the case of a 23-year-old pregnant woman with an incidentally detected 10 fold elevated serum ALP which was managed at a sub district level hospital which is a poor resource setting. She was expectantly managed and delivered a healthy new-born with an unremarkable intrapartum and post-partum period. Her ALP levels were monitored during the peri-partum period and gradually declined. This case is important because it shows that an isolated increase in a biochemical marker can give a good feto-maternal outcome after expectant and vigilant management.
Factors related to the death of diabetic patients with COVID-19 hospitalized in Joseph Raseta Befelatanana University Hospital in Antananarivo, Madagascar
Authors: Andrianiaina Miora M. A. , Randrianomanana Tsikinirina V. , Raherison Rija E. , Razanamparany Thierry , Raharinavalona Sitraka A. , Rafamatanantsoa Jean F. , Rakotomalala Andrianirina D. P. , Andrianasolo Radonirina L. 
Published: August 2022

Background: Diabetes mellitus is associated with severe and even fatal forms of COVID-19. The objective of this study was to identify the factors linked to the death of COVID-19 diabetic patients in order to improve their care.Methods: An analytical cross-sectional study was carried out in the endocrinology department of the Joseph Raseta Befelatanana University Hospital Center, Antananarivo, Madagascar. It has concerned all the cases of COVID-19 diabetics (162 patients) recorded from April 2020 to July 2021 (16 months).Results: In our study, the case fatality rate of COVID-19 in diabetics was 14.49%. Significant factors related to death, after univariate analysis, were: vascular complications including nephropathy (OR=4.74), neuropathy (OR=5.38) and ischemic heart disease (OR=3.9), presence of other comorbidities (OR=9.02), dyspnea (OR=4.60), seizures (OR=6.22) or alertness disorder (OR=4.35), lower oxygen saturation (p=0.04), pleurisy (OR=4.67), signs of cardiac decompensation (OR=3.46), an elevated mean blood sugar level (p<0.001), leukocytosis (p=0.02) and thrombocytopenia (p<0.001), impaired renal function (p=0.02) and pleurisy on chest imaging (OR=5.29).Conclusions: Death factors in diabetics with COVID-19 can be diverse. They do not only include the cardiovascular complications of the diabetes, but also a worse clinical respiratory presentation on the admission, a higher inflammatory syndrome, and a greater imbalance of blood sugar during the hospitalization.
A preceptoria em enfermagem na pandemia do COVID-19: relato de experiência em uma Unidade Básica de Saúde em Cacoal/RO
Authors: Reco Cruz Jessíca , Cesar Schweickardt Júlio , Rocha Ernandes Bianca Gabriela , Lopes de Sousa Cássia , Dantas Sara , Teodora Viana Teresinha Cicera , Lelis de Oliveira Wuelison , Chaddad Yamin Filho Marco Antonio 
Published: August 2022

No Brasil, a Atenção Primária à Saúde (APS) é uma das portas de entrada para pessoas com suspeita ou confirmação da COVID-19, sendo responsável pela coordenação do cuidado e monitoramento dos casos que apresentem sintomas leves. APS é também compo de ensino prático em enfermagem. Buscamos através do relato de experiência de um estágio supervisionado em enfermagem, numa cidade da Amazônia, estado de Rondônia, fazer alguns apontamentos dos tempos que vivemos. A vivência proporcionou a todos, acadêmicos e à preceptoria, uma visão diferenciada da Atenção Básica e da própria profissão. Desse modo, podemos dizer que a realização de um estágio e a preceptoria permitiu a reflexão sobre alguns aspectos que envolvem a pandemia: processos de trabalho, orientações sanitárias, educação permanente em saúde e os processos formativos.
O (IN)VISÍVEL NO (IN)VISÍVEL: UM OLHAR PSICANALÍTICO SOBRE A RELAÇÃO ENTRE A PANDEMIA DE COVID-19 E A VULNERABILIDADE SOCIAL
Authors: Moreira Francisco Jadson Franco 
Published: August 2022

A OMS declarou a COVID-19 em março de 2020, uma pandemia, quando todos os continentes confirmaram casos. Já foi detectado cerca de 330.000 casos em todo mundo, com mais de 14.000 óbitos, demonstrando sua transmissibilidade (número básico de reprodução - R0, estimado entre 1,4 a 5,5) e letalidade estimada em cerca de 4,1% (OMS, 2020).Objetivo: o estudo objetivou apresentar uma reflexão sobre Vulnerabilidade Social e Psicanálise no contexto da Pandemia na cidade de Fortaleza- Ceará- Brasil. Método: Trata-se de um estudo descritivo do tipo reflexivo, realizado em agosto de 2020, por meio de levantamento bibliográfico sobre a temática. Resultados: Apresentam reflexões sobre o laço social direcionado a aspecto da constituição humana e da sociedade em situação de vulnerabilidade social na luta contra o vírus invisível, o estudo elabora também correlações teóricas com conceitos da psicanálise. Considerações Finais pontua espaços de compreensão do ser humano, e oportunidades fundantes para refletir práxis, sobretudo do profissional de psicologia nos atuais dias. O (IN)VISÍVEL NO (IN)VISÍVEL: UM OLHAR PSICANALÍTICO SOBRE A RELAÇÃO ENTRE A PANDEMIA DE COVID-19 E A VULNERABILIDADE SOCIAL
Atenção Primária à Saúde e o contexto da pandemia de COVID-19: reflexões sobre o cuidado em saúde de pessoas idosas
Authors: Buno Carolina Da Silva , Bulgarelli Alexandre Favero 
Published: August 2022

O contexto global de emergência em saúde pública causada pela pandemia de COVID-19 desafia os diversos países a pensar estratégias para prevenção e controle da infecção por Sars-CoV-2. Os idosos são o principal grupo de risco para os casos mais agravados da doença, levando os sistemas de saúde a (re) pensarem seus modelos de atenção e propor estratégias capazes de responder as demandas pré-existentes destes usuários, somados às novas questões evidenciadas pela pandemia. Neste contexto, a Atenção Primária à Saúde (APS) é espaço estratégico para a oferta de cuidados de forma equânime e integral, sendo o principal ponto da rede de atenção acessado pelos usuários idosos. Com o advento da emergência em saúde pública pela COVID-19 este nível de atenção continuou sendo a referência para o atendimento de primeiro contato aos casos sintomáticos respiratórios leves e moderados. Frente tais contextos realizou-se um estudo com aproximação metodológica qualitativa, desenhada dentro de um método indutivo objetivando descrever o acesso aos serviços de saúde na atenção primária na perspectiva dos usuários idosos e traçar um paralelo com questões envolvendo a COVID-19. A produção de informações se deu por meio de entrevistas narrativas semiestruturadas, o material tratado e analisado à luz da técnica de Análise Temática de Conteúdo. Observa-se que houve o aumento das evasões de consultas de acompanhamento e complicações às condições de saúde pré-existentes dos usuários idosos, desafiando a APS a fortalecer as formas de cuidado centradas nos territórios, pautadas, também, na prevenção e promoção ao COVID-19. Novas estratégias para continuidade dos cuidados foram desenvolvidas e ganharam lugar no cotidiano do trabalho das equipes de APS, como as teleconsultas e telemonitoramentos. Sem estratégias que possibilitem outras formas de cuidado a pandemia de COVID-19 pode representar um fator dificultador de acesso dos usuários idosos aos serviços da atenção primária
Body-Mass Index-Based Effective Dose Determination in Commonly Performed Computed Tomography Examinations in Adults
Authors: Deevband Mohammad Reza , Hosseini Nasab Seyyed Mohammad Bagher , Mohammadi Habib , Salimi Yazdan , Mostaar Ahmad , Deravi Niloofar , Fathi Mobina , Vakili Kimia , Yaghoobpoor Shirin , Ghorbani Mahdi 
Published: August 2022

Purpose: With the widespread application of ionizing radiation in medical practice, concerns have been increased regarding the hazardous effects of radiation. Studies have demonstrated that some variables such as body dimensions affect the absorbed radiation dose. In this study, the association between Body Mass Index (BMI) and absorbed dose in Computed Tomography (CT) is investigated.
Materials and Methods: A total of 550 adult patients (age ≥ 15 years) were included in the study. The height and weight of the patients were recorded for BMI calculation. Dosimetry data were acquired from digital imaging and communications in medicine dose reports. The patients were categorized into five groups according to their BMI, the categorized information was then imported into ImPACT Dose software for calculation of Size-Specific Dose Estimate (SSDE) and organ and effective doses. The relationship between patient BMI and the effective dose was also determined.
Results: A higher BMI contributed to increased radiation dose and SSDE in patients who had undergone chest or abdomen-pelvis CT examination (p < 0.05).
Conclusion: The radiation dose is related to a patient’s BMI and rises with an increase in BMI. Accordingly, it is suggested that BMI and other variables, such as the type of scan and other body dimensions, which affect the radiation dose, can be used to estimate the radiation dose before performing CT. This estimation can be considered for the justification and optimization of CT examinations.
Cidade Inteligente e Inteligência de Dados. Análise do aplicativo NOA Cidadão da Prefeitura Municipal de Salvador
Authors: Lemos André , Moura Thalis 
Published: August 2022

Este artigo analisa a inteligência de dados desenvolvida pelo NOA Cidadão, aplicativo da Transalvador/Prefeitura Municipal do Salvador (PMS), no projeto “Salvador 360”. A partir de uma perspectiva neomaterialista (FOX; ALLDRED, 2017) realizamos: a) Análise da interface; b) Análise de conteúdo dos documentos oficiais e comunicações públicas; e c) Análise de reação dos usuários na plataforma Google Play Store com auxílio da ferramenta Appbot. Conclui-se que o aplicativo mobiliza uma abrangente rede, articulando dados, processos, instituições, agentes e equipamentos. Concluímos apontando que o aplicativo NOA Cidadão é um dispositivo-rede que depende tanto da disposição do usuário em fornecer dados, quanto de outras instituições e dos servidores da Transalvador para funcionar como um aplicativo inteligente.
Delineating Masculinity Belief in Guy de Maupassants’ Three Short Stories
Authors: Kasih Elisabeth Ngestirosa Endang Woro , Husna Mufaza , Mulia Muhammad Rizki , Fithratullah Muhammad 
Published: August 2022

This study aims to delineate masculinity issues in Guy Maupassant’s Father Milon, A Duel and The Coloniel’s Ideas short stories. This study sees that the practice of masculinity in the society legitimizes the dominant position of men and justifies the subordination of the male and female population in general and other marginalized ways of being male. This study employed Stuart Hall’s representation and Gramsci’s hegemony theories to delineate masculinity in Maupassants’ three short stories. The qualitative descriptive method was applied as the data were in the form of narration and dialogues. The short stories revealed the dominant position of men in society that justifies the subordination of the male and female population in general. Finally, with the creation of different male characters with various degree of masculine nature, Guy Maupassant in Father Milon, A Duel and The Coloniel’s Ideas tries to balance the male character he creates. Maupassant is just trying to paint pictures of different kinds the man seen in society, therefore, confirms the verisimilitude between characters in literary works and real-life characters.
Low Genetic Diversity Study on Leopard Coral Grouper Plectropomus leopardus (Perciformes: Serranidae) from Sulawesi, Indonesia
Authors: Hidayani Andi Aliah , Tasakka Asmi Citra Malina A. R. , Umar Widyastuti , Alam Md. Jobaidul , Neogi Amit Kumer , Andriyono Sapto 
Published: August 2022

Highlight ResearchThe leopard coral grouper Plectropomus leopardus was identified and analysed based on molecular approach.Genetic diversity within two regions in Gorontalo, Sulawesi successfully performed using connectivity analysis.Three haplotypes of Plectropomus leopardus from two region in Gorontalo as one of economical important marine fish species. AbstractBar-cheek coral trout (P. leopardus) is the flagship of the grouper in the live fish market in Asia. Unfortunately, the potential of the grouper is still partly produced from natural catches. Even though hybridisation activities have also started to be carried out, there still have not been many studies on the genetic diversity of these fish. The application of molecular identification has been widely applied in marine aquatic animal species, which are very likely to occur due to errors in terms of shape and colour in the morphological character. DNA information has been beneficial in efforts to the breeding program and develop grouper aquaculture activities. DNA barcoding was used for the molecular identification and haplotype analysis of P. leopardus from two locations in Gorontalo, Sulawesi, Indonesia. A total of 14 fish samples were collected from two traditional fish markets around Kwandang and Sumalata Gulf in the northern part of Gorontalo Province, Sulawesi. This study identified and found three haplotypes from both regions. Molecular identification using Cytochrome c Oxidase subunit I (COI) gene region on mitochondrial DNA. Besides Mega7 for phylogenetic reconstruction, the data analysis using DnaSP6, Arlequin Ver.3.5.2.2, and Network 5.0.1.1. The first Haplotype is a mixed population between the Kwandang Gulf and the Sumalata Gulf, then the Kwandang Gulf haplotype and the Sumalata Gulf haplotype. The genetic distance between Kwandang Gulf haplotype and Sumalata Gulf haplotype is 0.003984, classified as a shallow genetic distance and needs more samples from another region to figure out leopard coral grouper around Indonesia.
Effect of Maggot Flour (Hermetia illucens larvae) on Histopathology of Koi carp <I>(Cyprinus carpio)</I> Muscles and Gills Infected with <I>Edwarsiella tarda</I>
Authors: Pradana Hengki , Prajitno Arief , Maftuch Maftuch 
Published: August 2022

Highlight Research

Feeding of maggot flour formulations to koi carp infected with tarda
Active compounds contained in maggot
Clinical symptoms of koi carp infected with tarda
Damage to the muscle and gill tissue of koi carp infected with E. tarda

Abstract
The problem that fishes farmers often face is disease. Maggot contains a high protein which ranges from 41-42%. Besides that, maggot also has a good effect on increasing the body resistance of fish. While the maggot provision fulfills nutritional need, it’s also expected to boost immunity against bacterial disease. One of which is Edwardsiella tarda, known to infect koi carp (Cyprinus carpio). Feeding of maggot flour at different doses, namely A (25%), B (50%), C (75%), and D (100%) was carried out to determine its effect on the histopathology of the muscles and gills of C. carpio infected with E. tarda. Water quality during the study obtained an average value, namely the temperature ranging from 26-27.5℃, pH 6.5-8.1, and DO 5.2-8 mg/L. Fish infected with E. tarda showed several clinical symptoms, including rapid operculum movement, irregular and slow swimming, and bleeding on the skin. The results of the histopathological analysis showed that in muscle and gill tissue, treatment C (75%) showed the lowest damage value among other treatments with an average score of necrosis 0.93, hyaline degeneration 1.33, and Edema 1.27. Average score of gill tissue damage was 0.9 fusion, 1.3 congestion, 0.9 hyperplasia. Based on this, the provision of maggot flour can be used to prevent infection of E. tarda against C. carpio.
Effects of Urea Removal on the Stable Isotopes δ13C and δ15N in Rays from the Coastal Waters of Peninsular Malaysia
Authors: Abdullah Maizah Mohd , Yien Lua Wei , Mostapha Roslanzairi , Bashir Zalina , Naimullah Mohd , Hajisamae Sukree , Hisam Fazrul 
Published: August 2022

Highlight Research

This is the first stable isotopes study of rays from Malaysian waters
Urea extraction significantly enriched the δ15N values (‰)
Urea removal is obliged for stable isotope studies on rays
Such methodological information is critical for marine research in the region

Abstract
This is the first reported record of stable isotope values for elasmobranch rays within Malaysian waters, and serves as an important baseline methodological information for future studies investigating stable isotope values in both shark and ray species in the region. This study examined the effects of urea removal on the stable isotopes values of δ13C and δ15N in muscle tissues sampled from several elasmobranch rays species, namely Pastinachus atrus, Rhinoptera javanica, Himantura gerrardi, Himantura uarnak and Aetobatus ocellatus. Individual ray species were collected in July and August of 2018, from the coastal waters of Terengganu State, Malaysia. Urea removal was performed by soaking muscle tissue samples in deionised water for at least 24 hours before being dehydrated. The resulting stable isotope values of these samples were compared to samples that did not undergo the urea removal process. Stable isotope values were individual and species-specific, however, the effect of urea removal was significant for δ15N values but did not significantly affect the δ13C values. We conclude that removing urea from elasmobranch samples before stable isotope analysis is advisable to draw correct conclusions about the animal’s diets.
The Activity of Mixed Microalgae Polysaccharides from Indonesia as Anti-Malaria in Vitro
Authors: Pujiyanto Mahendra , Afililla Zhaza , Maslachah Lilik , Widiyatno Thomas Valentinus , Koerniawan Mochamad Donny , Suyono Eko Agus , Budiman Arief , Siregar Ulfah Juniarti , Suwanti Lucia Tri 
Published: August 2022

Highlight Research

One of the content of microalgae that is beneficial for health is polysaccharides
Polysaccharides of Indonesian microalgae can be promoted as anti-malarial
Polysaccharides from Glagah, Spirulina and East Java microalgae inhibited the growth of plasmodium in vitro and had IC50 values of 3.18 µg/mL, 5.43µg/mL and 9.87 µg/mL, respectively

Abstract
Malaria is an infectious disease caused by protozoan parasites of the genus Plasmodium that categorized as deadliest diseases in the world. Artemisinin and its derivatives are still recommended drugs for malaria therapy, however, there have been indications that Plasmodium parasites are resistant to this drug. Therefore, a study on polysaccharides from microalgae may be a potential as bioactive compound for anti-malaria. The aim of this study was to determine the effectiveness of the mixed microalgae polysaccharides as anti-malarial in vitro. Polysaccharides were extracted from three microalgae Spirulina sp., mixed microalgae Glagah and mixed microalgae East Java using the alkaline extraction method. The anti-malarial activity test refers to the concentration of polysaccharides used in calculating the IC50 value by probit analysis. The concentration of polysaccharides of the three microalgae used were 0; 0.01; 0.01, 1, 10 and 100 µg/mL. The results showed that the IC50 values of polysaccharides of Glagah, Spirulina sp. and East Java microalgae were 3.18 µg/mL, 5.43µg/mL, and 9.87 µg/mL, respectively. In Conclusion, polysaccharides of Indonesian mixed microalgae can be promoted as anti-malarial.
Autoclaving and Alkaline Hydrolysis Effects on the Particle Size and Solubility of Grouper (<I>Epinephelus</I> sp.) Nano-calcium Powder in <I>In Vitro</I> Gastrointestinal Tract Simulation
Authors: Kusumawati Pipin , Triwitono Priyanto , Anggrahini Sri , Pranoto Yudi 
Published: August 2022

Highlight Research

Autoclaving for 3x3 hours followed by alkaline hydrolysis (3x3AH) may lower nano-calcium particle size into 47.47 nm
3x3AH sample contain 30.73% calcium and 18.37% phosphorus
3x3AH sample created the best calcium solubility (26.14 %) in comparison to synthesized CaCO3 (14.34 %)
Grouper nano-calcium powder includes trace quantities of organic content, such as protein and fat, which enhance calcium's solubility.

Abstract
Fish bone nano-calcium production may solve two challenges, providing calcium for lactose-intolerant people and recycling bone waste. Fish bone autoclaving prior to extraction reduces fat, denatures collagen, and softens bones but only few researches have compared autoclaving duration with nano-calcium product quality, particle size, and its solubility in in vitro testing. This study studied the influence of autoclaving duration followed by alkaline hydrolysis on nano-calcium characteristics to enhance calcium solubility in in vitro gastrointestinal simulation experiments. The dried grouper (Epinephelus sp.) bone was divided into four groups: 0A (no autoclaving), 3A (3 h autoclaving), 2x3A (double cycle for 3 h autoclaving), and 3x3A (triple cycle for 3 h autoclaving). Each group was followed by alkaline hydrolysis, designated as 0AH, 3AH, 2x3AH, and 3x3AH. The results showed that autoclaving for 3x3 hours followed by alkaline hydrolysis resulted in lowest nano-calcium particle size of 47.47 nm consisting of 30.73% calcium and 18.37% phosphorous. 3x3AH sample created the best calcium solubility (26.14%) in comparison to synthesized CaCO3 (14.34%). In contrast to synthetic CaCO3, grouper nano-calcium powder includes trace quantities of organic contents, such as protein and fat, which enhance calcium solubility. In vivo research should be established to study the bioavailability and influence of grouper nano-calcium powder on bone density.
Cine MRI Is Useful for the Diagnosis of Intradural Arachnoid Cyst with Spinal Arachnoid Web
Authors: Kawaguchi Hiroshi , Ono Koichiro , Takabayashi Naoya , Ito Toshihiko , Harada Kazuhiro , Sudo Yoshihiro , Kim Yong , Nakajima Takao , Miyamoto Masabumi , Majima Tokifumi 
Published: August 2022

Case:
A 28-year-old woman developed gait disturbance due to lower limb weakness 3 years before presentation. Conventional magnetic resonance imaging (MRI) findings were inconclusive; therefore, we performed cine MRI, which confirmed the presence of a pulsatile cyst on the posterior thoracic spinal cord. The cyst compressed the spinal cord, and its pulsations synchronized with the patient's heartbeats. We resected the intradural arachnoid cyst and thickened arachnoid membrane. The gait disturbance improved after surgery.

Conclusions:
Cine MRI can be used to identify a pulsating arachnoid cyst that cannot be visualized with a conventional MRI. Cine MRI is useful in patients with unexplained spinal symptoms.