bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tinjauan Pengaturan Hukum Konservasi Sumber Daya Alam Hayati dalam Berbagai Putusan Mahkamah Konstitusi
Authors: Wahanisa Rofi 
Published: February 2022

Undang-Undang No. 5 Tahun 1990 tentang Konservasi sumber daya alam hayati dan ekosistemnya (UU KSDHE) haruslah relevan dan selaras dengan berbagai peraturan perundang-undangan dan Putusan Mahkamah Konstitusi (Putusan MK). Adapun permasalahan dalam penelitian ini adalah : 1) Bagaimanakah keselarasan antara Undang-undang Konservasi Sumber Daya Alam Hayati dan Ekosistem (KSDHE) dengan peraturan perundang-undangan lainnya?, 2) Bagaimanakah Undang-undang Konservasi Sumber Daya Alam Hayati dan Ekosistem (UU KSDHE) ditinjau dari putusan Mahkamah Konstitusi?. Penelitian ini merupakan penelitian normatif dengan pendekatan konseptual dan pendekatan peraturan perundang-undangan. Data yang digunakan adalah data sekunder. Analisis data didasarkan pada model interaktif. Hasil studi menunjukkan bahwa : (1) UU KSDHE tidak mempertimbangkan UUPA dan TAP MPR No. IX/MPR/2001 sebagai landasan pengaturan sumber daya alam. Terjadi pula ketidakselarasan antara substansi UU KSDHE dengan peraturan lainnya. Peraturan ini juga tidak responsif karena belum mengatur mengenai bioteknologi modern dan pemanfaatan sumber daya genetika. (2) UU KSDHE tidak selaras dengan putusan-putusan Mahkamah Konstitusi yang menekankan pada aspek preventif dalam pengelolaan sumber daya alam, perlindungan dan penghormatan terhadap hak masyarakat hukum adat serta partisipasi publik yang substantif. Di sisi lain, UU KSDHE masih menekankan pada aspek penertiban (kuratif), tidak memberikan perlindungan terhadap pengelolaan dan pemanfaatan kawasan konservasi oleh masyarakat hukum adat serta partisipasi publik yang hanya berada dalam tingkatan informing. Studi ini merekomendasikan revisi terhadap UU KSDHE agar selaras dengan Putusan Mahkamah Konstitusi.
Jako obiekt, jako subiekt. Kobiety w polskich hasłach politycznych XX i XXI wieku
Authors: Śleziak Marta 
Published: February 2022

Autorka artykułu omawia specyfikę kobiecych haseł politycznych – takich, które są skierowane do kobiet, takich, których autorkami są kobiety, oraz takich, które niebezpośrednio odnoszą się do kobiet. Materiał badawczy obejmuje hasła (slogany) polityczne z lat 1918–2020, prezentowane zarówno w tekstach pisanych (na drukach ulotnych, w prasie, na transparentach eksponowanych podczas manifestacji), jak i w tekstach mówionych (przemówieniach polityków, hasłach skandowanych podczas wieców i demonstracji). Szczegółowo zaprezentowane zostały dwa aspekty haseł: pragmatyczny, przedstawiający zmieniającą się rolę polskich kobiet jako uczestniczek dyskursu politycznego i publicznego, oraz formalny, związany z kształtem językowym analizowanych przekazów. W badaniach ujawniły się następujące tendencje: zmienna w czasie aktywność kobiet, osiągająca swoje apogeum w drugiej dekadzie XXI wieku, oraz ewoluowanie form haseł od poetyki wezwania i nakazu do uogólniających sloganów, silnie nawiązujących do innych tekstów kultury.
Speech-Language Pathologists’ Collaboration with Interpreters: How to Reach Successful Outcomes
Authors: Langdon Henriette W. , Sanez Terry Irvine 
Published: February 2022

Conducting a speech and language assessment with the mediation of an interpreter is one of the greater challenges facing speech-language pathologists (SLPs)1 both in the United States and worldwide when needing to assess linguistically and culturally different clients (McLeod & Verdon, 2017; Santhanam & Parveen, 2018). The process requires the collaboration of three parties: the service provider, in this case, the speech-language pathologist, the consumer (the client and/or parent, relative or spouse) and the interpreter. This paper provides an overview of the literature on perspectives of educational and medical speech-language pathologists and process and presents an outline of a program to train both the interpreter and the speech-pathologist simultaneously to reach a successful collaborative outcome.
Frecuencia del biotipo facial en estudiantes de la carrera de Odontología de la UTE
Authors: Parise Vasco Juan Marcos 
Published: February 2022

Introducción: Establecer el biotipo facial del paciente es esencial en varias áreas de la odontología, al permitirnos diseñar un mejor plan de tratamiento y conductas a seguir, busca evitar errores en la planificación y desarrollo del tratamiento. Objetivo: Determinar la prevalencia de los diferentes biotipos faciales en estudiantes de la carrera de Odontología de la Universidad UTE, mediante el análisis cefalométrico de Ricketts y aplicación del índice VERT. Métodos: Se planteó un estudio transversal descriptivo, considerando una muestra constituida por 79 estudiantes de últimos niveles de los periodos académicos 2018-2019. Cada participante fue sometido a un examen clínico para la valoración de hipertrofia amigdalar y desórdenes en la articulación temporomandibular. Para determinar el biotipo facial y patrón esqueletal se utilizó el análisis cefalométrico de Ricketts con el índice VERT. Los datos recolectados fueron analizados mediante estadística descriptiva, análisis de frecuencias, medidas de tendencia central y de dispersión. Resultados: El biotipo facial de mayor prevalencia fue el mesofacial.
Prueba de micronúcleos en células bucales. Una revisión
Authors: COLCHADO CARHUAVILCA JORGE RAÚL 
Published: February 2022

La prueba de micronúcleos se ha convertido en el método más utilizado para evaluar la genotoxicidad de diferentes factores biológicos, físicos y químicos, convirtiéndose poco a poco en un reconocido marcador de daño en el ADN para el biomonitoreo de diversas entidades sistémicas. Esta revisión está enfocada principalmente en la prueba de micronúcleos en células bucales, considerado en la actualidad como una prueba prometedora para ser utilizada como biomarcador de eventos patológicos, por las características que presenta al no ser invasiva, tolerada por lo pacientes y no requerir de una infraestructura compleja, como equipos de cultivo tisular, para llevarla a cabo. Como se sabe el fundamento de esta prueba es la detección de los micronúcleos, los cuales se originan a partir de cromosomas completos o fragmento de cromosomas que fueron rezagados por genotoxinas durante la mitosis.

Palabras clave. Micronúcleos, Mucosa bucal, Pruebas de mutagenicidad, ADN.
Tercer molar retenido, un problema de salud pública (Análisis antes y durante y durante la enfermedad Covid-19).
Authors: Enríquez Méndez Silvana , Palacios Vivar Diego , Vargas Chávez Luis 
Published: February 2022

Los cambios que hemos sufridos los humanos, por la mezcla racial, herencia, cambios en los hábitos alimenticios, conducen a una incidencia cada vez más elevada de retención de piezas dentales y su consiguiente patología multisintomática. Las diversas indicaciones para realizar la extracción del tercer molar retenido son: alteraciones ortodónticas, protésicas restaurativas, periodontales o bien por una patología asociada (quistes, tumores ontogénicos, fracturas, infecciones). El objetivo del presente artículo es evaluar el tratamiento temprano del tercer molar retenido. Además se analizará brevemente el costo de su tratamiento quirúrgico y recuperación posoperatoria, abarcando desde medicación hasta el descuento del sueldo mensual que puede provocar la ausencia del paciente a su trabajo.
Managing System Of Diesel Fuel Provision By Mapping Fisherman Activities
Authors: Sahulata Reynoldus Andrias , Sunarya Po Abas 
Published: February 2022

The certainty of getting diesel fuel oil for the purposes for fishing of fishermen needs to get serious attention from the government, this is due to the many irregularities seen in the fishermen's field before going to sea, to get diesel must deal with the availability of diesel with an affordable price level especially for fishermen who use fishing vessels with volumes of up to 30GT (Gross Ton) must deal with individuals who regulation seaworthy letters that ignore Article 86 of the Minister of Marine Affairs and Fisheries Regulation No. 30 of 2012 concerning Capture Fisheries Business in the Republic of Indonesia's Fisheries Management Area Indonesia is in the form of a Fishing License (SIPI) and a Fishing Vessel License (SIKPI), an Original Operation Feasibility Certificate (SLO) and an Original Sailing Certificate (SPB), which makes it difficult to obtain subsidized diesel fuel that fishermen should have with vessel qualifications up to 30GT. For this reason, the researchers built of arrangement for computerized fishermen's diesel fuelsupply so that the certainty of the availability of diesel fuel in accordance with its designation can be ensured, because all supply and distribution of diesel fuel is regulated to be carried out computerized.
Perceptions and Knowledge of Self-Regulation of Paramedics in Australia
Authors: Reed Buck , Cowin Leanne , O'Meara Peter , Wilson Ian 
Published: February 2022

Introduction Since 2018, paramedics in Australia have been self-regulated under the National Registration and Accreditation Scheme (NRAS) for health professionals. While paramedics and other health practitioners are self-regulated in many jurisdictions internationally, there has been little study of the impact on practitioners of the introduction of new regulatory frameworks. Method Paramedics undertook a survey in the month leading up the commencement of self-regulation collecting both qualitative and quantitative data. The survey was completed by 419 participants. This paper explores the analysis of quantitative data. Key results were cross-tabulated with demographic factors. Results Participants indicated they had good broad knowledge of the regulatory scheme but were less confident on more detailed aspects. Most believed that patient safety and practitioner accountability will improve with registration however results were less clear on changes in scope, remuneration or employment opportunities. Questions on identity indicated that the primary factors in paramedic identity construction were employment status, qualifications and scope with impending registration the least important factor. Overall, 59% of participants supported self-regulation, however 25% indicated they held negative views. When cross-tabulated with demographics, years of service and initial qualification (vocational vs university) showed relationships with support for regulation. Conclusion The introduction of self-regulation represents significant change to both the governance of paramedics and entry to the profession. Uncertainty By some is indicative of the unique nature and impact of the change. However, there is wide agreement that the scheme will increase safety and accountability which are the key aims of professional regulation.
A One-Step Electropolymerized Biomimetic Polypyrrole Membrane-Based Electrochemical Sensor for Selective Detection of Valproate
Authors: Yuan Yuyang , Li Tianyu , Ye Zhichao , Feng Yuyao , Chen Zhe , Wang Yusen , Sun Yiqiao , Wu Haoyu , Yang Zhaodong , Wang Yifan , Zhang Yiran , Huang Liquan , Liang Bo 
Published: February 2022

Bipolar disorder is a chronic mental disease with a heavy social and economic burden that causes extreme mood swings in patients. Valproate is a first-line drug for bipolar disorder patients to stabilize their daily mood. However, an excessive amount of valproate in the blood could induce severe adverse effects, which necessitates the monitoring of blood valproate levels for patients. Here, we developed an innovative electrochemical sensor for selective and simple detection of valproate based on a molecularly imprinted polymer membrane via one-step electropolymerization. Gold nanoparticles were electrochemically modified to the screen-printed electrode under the selective membrane to enhance its conductivity and stability. The successfully fabricated biosensor was characterized by scanning electron microscopy, cyclic voltammetry, and differential pulse voltammetry methods. The binding of the target molecules to the valproate-customized biomimetic polypyrrole membrane blocks cavities in the membrane and alters its electric properties, which can be detected as a decrease in the peak current by differential pulse voltammetry method. The peak current change presents a great log-linear response to the valproate concentration around the therapeutic window. The limit of detection of this method was 17.48 μM (LOD, S/N = 3) and the sensitivity was 31.86 μM μA−1. Furthermore, the biosensors exhibited both satisfying specificity with the interference of other psychological pharmaceutical drugs and uniformity among sensors, indicating their potential and reliability in translational application. This simple and reliable method of sensing valproate molecules primarily provides an exceptional solution to valproate point-of-care testing in clinical practice.
Mechanochemical Preparation, Characterization and Biological Activity of Stable CuS Nanosuspension Capped by Bovine Serum Albumin
Authors: Stahorský Martin , Lukáčová Bujňáková Zdenka , Dutková Erika , Kello Martin , Mahlovanyi Bohdan , Shpotyuk Yaroslav , Daneu Nina , Trajić Jelena , Baláž Matej 
Published: February 2022

The biocompatible nanosuspension of CuS nanoparticles (NPs) using bovine serum albumin (BSA) as a capping agent was prepared using a two-stage mechanochemical approach. CuS NPs were firstly synthetized by a high-energy planetary ball milling in 15 min by milling elemental precursors. The stability of nanoparticles in the simulated body fluids was studied, revealing zero copper concentration in the leachates, except simulated lung fluid (SLF, 0.015%) and simulated gastric fluid (SGF, 0.078%). Albumin sorption on CuS NPs was studied in static and dynamic modes showing a higher kinetic rate for the dynamic mode. The equilibrium state of adsorption was reached after 90 min with an adsorption capacity of 86 mg/g compared to the static mode when the capacity 59 mg/g was reached after 2 h. Then, a wet stirred media milling in a solution of BSA was introduced to yield the CuS-BSA nanosuspension, being stable for more than 10 months, as confirmed by photon cross-correlation spectroscopy. The fluorescent properties of the nanosuspension were confirmed by photoluminescence spectroscopy, which also showed that tryptophan present in the BSA could be closer to the binding site of CuS than the tyrosine residue. The biological activity was determined by in vitro tests on selected cancer and non-tumor cell lines. The results have shown that the CuS-BSA nanosuspension inhibits the metabolic activity of the cells as well as decreases their viability upon photothermal ablation.
Diagnostic and Prognostic Value of Neutrophil Extracellular Trap Levels in Patients With Acute Aortic Dissection
Authors: Yang Shuofei , Xiao Yongsheng , Du Yuanfeng , Chen Jiaquan , Ni Qihong , Guo Xiangjiang , Xue Guanhua , Xie Xupin 
Published: February 2022

BackgroundAcute aortic dissection (AAD) is a fatal disease demanding prompt diagnosis and proper treatment. There is a lack of serum markers that can effectively assist diagnosis and predict prognosis of AAD patients.MethodsNinety-six AAD patients were enrolled in this study, and 249 patients with chest pain due to acute myocardial infarction, pulmonary embolism, intramural hematoma, angina or other causes and 80 healthy controls were included as control group and healthy control group. Demographics, biochemical and hematological data and risk factors were recorded as baseline characteristics. The 1-year follow-up data were collected and analyzed. The diagnostic performance and ability to predict disease severity and prognosis of NET components in serum and aortic tissue were evaluated.ResultsCirculating NET markers, citH3 (citrullination of histone 3), cell-free DNA (cfDNA) and nucleosomes, had good diagnostic value for AAD, with superior diagnostic performance to D-dimer in discriminating patients with chest pain due to other reasons in the emergency department. Circulating NET marker levels (i.e., citH3, cfDNA and nucleosomes) of AAD patients were significantly higher than that of control group and healthy control group. In addition, circulating NET markers levels were closely associated with the disease severity, in-hospital death and 1-year survival of AAD patients. Systolic blood pressure &lt; 90 mmHg and serum citH3 levels were identified as independent risk factors for 1-year survival of AAD patients. Excessive NET components (i.e., neutrophil elastase and citH3) in the aortic tissue of AAD patient were significantly higher than that of healthy donor aortic tissue. The expression levels of granules and nuclear NET components were significantly higher in aortic tissue from AAD patients than controls.ConclusionsCirculating NET markers, citH3, cfDNA and nucleosomes, have significant diagnostic value and predictive value of disease severity and prognosis of AAD patients. The NETs components may constitute a useful diagnostic and prognostic marker in AAD patients.
Evaluation of the Oxiris Membrane in Cardiogenic Shock Requiring Extracorporeal Membrane Oxygenation Support: Study Protocol for a Single Center, Single-Blind, Randomized Controlled Trial
Authors: Andrei Stefan , Nguyen Maxime , Berthoud Vivien , Morgant Marie-Catherine , Bouhemad Belaid , Guinot Pierre-Grégoire ,   The ECMORIX Study Group
Published: February 2022

Background: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is the rescue treatment proposed to patients with refractory cardiogenic shock. The VA-ECMO implantation promotes inflammation and ischemia-reperfusion injuries through the VA-ECMO flow, causing digestive mucosa barrier disrupture and inducing translocation of bacterial wall components—Lipopolysaccharides (LPS) with further inflammation and circulatory impairment. LPS is a well-studied surrogate indicator of bacterial translocation. Oxiris membrane is a promising and well-tolerated device that can specifically remove LPS. The main study aim is to compare the LPS elimination capacity of Oxiris membrane vs. a non-absorbant classical renal replacement (RRT) membrane in patients with cardiogenic shock requiring VA-ECMO.Methods: ECMORIX is a randomized, prospective, single-center, single-blind, parallel-group, controlled study. It compares the treatment with Oxiris membrane vs. the standard continuous renal replacement therapy care in patients with cardiogenic shock support by peripheral VA-ECMO. Forty patients will be enrolled in both treatment groups. The primary endpoint is the value of LPS serum levels after 24 h of treatment. LPS serum levels will be monitored during the first 72 h of treatment, as clinical and cardiac ultrasound parameters, biological markers of inflammation and 30-day mortality.Discussion: Oxiris membrane appears to be beneficial in controlling the VA-ECMO-induced ischemia-reperfusion inflammation by LPS removal. ECMORIX results will be of major importance in the management of severe cases requiring VA-ECMO and will bring pathophysiological insights about the LPS role in this context.Clinical Trial Registration:www.ClinicalTrials.gov, identifier: NCT04886180.
Drainage From Superior Vena Cava Improves Upper Body Oxygenation in Patients on Femoral Veno-Arterial Extracorporeal Membrane Oxygenation
Authors: Cai Tong , Li Chenglong , Xu Bo , Wang Liangshan , Du Zhongtao , Hao Xing , Guo Dong , Xing Zhichen , Jiang Chunjing , Xin Meng , Wang Pengcheng , Fan Qiushi , Wang Hong , Hou Xiaotong 
Published: February 2022

ObjectiveTo investigate the feasibility of drainage from the superior vena cava (SVC) to improve upper body oxygenation in patients with cardiogenic shock undergoing femoral veno-arterial extracorporeal membrane oxygenation (VA ECMO).MethodsSeventeen adult patients receiving peripheral femoral VA ECMO for circulatory support were enrolled. The femoral drainage cannula was shifted three times (from the inferior vena cava (IVC) level to the SVC level and then the IVC level again), all under ultrasound guidance, at an interval of 15 minutes. The blood gas levels of the right radial artery (RA) and SVC and cerebral oxygen saturation (ScO2) were measured and compared.ResultsFifteen patients (88.2%) were successfully weaned from ECMO, and 12 patients (70.6%) survived to discharge. The oxygen saturation (SO2) and oxygen partial pressure (PO2) of the RA (97.0 ± 3.5% to 98.3 ± 1.5%, P &lt; 0.05, SO2; 127.4 ± 58.2 mmHg to 153.1 ± 67.8 mmHg, P &lt; 0.05, PO2) and SVC (69.5 ± 9.0% to 75.7 ± 8.5%, P &lt; 0.05, SO2; 38.5 ± 5.6 mmHg to 43.6 ± 6.4 mmHg, P &lt; 0.05, PO2) were increased; ScO2 was also increased on both sides (left: 50.6 ± 8.6% to 55.0 ± 9.0%, P &lt; 0.05; right: 48.7 ± 9.2% to 52.3 ± 9.8%, P &lt; 0.05) when the femoral drainage cannula was shifted from the IVC level to the SVC level. When the femoral drainage cannula was shifted from SVC level to the IVC level again, the SO2 and PO2 of RA (98.3 ± 1.5% to 96.9 ± 3.2%, P &lt;0.05, SO2; 153.1 ± 67.8 mmHg to 125.8 ± 63.3 mmHg, P &lt;0.05, PO2) and SVC (75.7 ± 38.5% to 70.4 ± 7.6%, P &lt;0.05, SO2; 43.6 ± 6.4 mmHg to 38.9 ± 4.5 mmHg, P &lt;0.05, PO2) were decreased; ScO2 was also reduced on both sides (left: 55.0 ± 9.0% to 50.7 ± 8.2%, P &lt; 0.05; right: 52.3 ± 9.8% to 48.7 ± 9.3%, P &lt;0.05).ConclusionDrainage from the SVC by shifting the cannula upward could improve upper body oxygenation in patients with cardiogenic shock undergoing femoral VA ECMO. This cannulation strategy provides an alternative solution for differential hypoxia.
Abutting Left Atrial Appendage and Left Superior Pulmonary Vein Predicts Recurrence of Atrial Fibrillation After Point-by-Point Pulmonary Vein Isolation
Authors: Szegedi Nándor , Simon Judit , Szilveszter Bálint , Salló Zoltán , Herczeg Szilvia , Száraz Lili , Kolossváry Márton , Orbán Gábor , Széplaki Gábor , Nagy Klaudia Vivien , Mahdiui Mohammed El , Smit Jeff M. , Delgado Victoria , Bax Jeroen J. , Maurovich-Horvat Pál , Merkely Béla , Gellér László 
Published: February 2022

IntroductionThe role of the spatial relationship between the left superior pulmonary vein (LSPV) and left atrial appendage (LAA) is unknown. We sought to evaluate whether an abutting LAA and LSPV play a role in AF recurrence after catheter ablation for paroxysmal AF.MethodsConsecutive patients, who underwent initial point-by-point radiofrequency catheter ablation for paroxysmal AF at the Heart and Vascular Center of Semmelweis University, Budapest, Hungary, between January of 2014 and December of 2017, were enrolled in the study. All patients underwent pre-procedural cardiac CT to assess left atrial (LA) and pulmonary vein (PV) anatomy. Abutting LAA-LSPV was defined as cases when the minimum distance between the LSPV and LAA was less than 2 mm.ResultsWe included 428 patients (60.7 ± 10.8 years, 35.5% female) in the analysis. AF recurrence rate was 33.4%, with a median recurrence-free time of 21.2 (8.8–43.0) months. In the univariable analysis, female sex (HR = 1.45; 95%CI = 1.04–2.01; p = 0.028), LAA flow velocity (HR = 1.01; 95%CI = 1.00–1.02; p = 0.022), LAA orifice area (HR = 1.00; 95%CI = 1.00–1.00; p = 0.028) and abutting LAA-LSPV (HR = 1.53; 95%CI = 1.09–2.14; p = 0.013) were associated with AF recurrence. In the multivariable analysis, abutting LAA-LSPV (adjusted HR = 1.55; 95%CI = 1.04–2.31; p = 0.030) was the only independent predictor of AF recurrence.ConclusionAbutting LAA-LSPV predisposes patients to have a higher chance for arrhythmia recurrence after catheter ablation for paroxysmal AF.