bluuebunny/crossref_metadata_2025_split huggingface dataset:
DYNAMICS OF PIGMENTS CONTENT IN SILPHIUM PERFOLIATUM L. LEAVES DEPENDING ON THE PHASE OF DEVELOPMENT AND SEASONAL FACTORS
Authors: Davidyants Eleonora Sergeyevna , Kravtsov Viktor Vasil'yevich 
Published: April 2022

The paper presents the results of studying the dynamics of the content of pigments in the leaves of Silphium perfoliatum L. (family Asteraceae), growing in the zone of unstable moisture of the Central Ciscaucasia, depending on the phase of development and seasonal factors. S. perfoliatum is a valuable forage, melliferous and flower-ornamental crop, which is also of interest as a source of various biologically active substances: terpenoids, triterpene saponins, polyphenols, polysaccharides, and others. Using the spectrophotometric method, the content of chlorophyll a, chlorophyll b, and the amount of carotenoids were determined in the leaves of S. perfoliatum variety Alena during 3 growing seasons (2018–2020 years). Changes in the content of pigments in plant leaves with a change in phenological phases have been established. The maximum content of total chlorophyll and total carotenoids in leaves was observed in the budding phase and over the years of the study averaged 0.75% and 0.15%, respectively (based on the absolutely dry weight of raw materials), in the flowering phase the amount of pigments slightly decreased and reached a minimum in the fruiting phase (0.52 and 0.12%, respectively). The content of pigments in leaves also depended on seasonal factors and increased with improved moisture conditions, which, in turn, depended on the amount of precipitacion.
A sufficiently high level of pigment content in the leaves of Silphium perfoliatum L. allows us to consider them as a promising medicinal raw material containing chlorophyll and carotenoids, the collection of which should be carried out in the budding phase.
Glycated albumin in diabetes mellitus: a meta-analysis of diagnostic test accuracy
Authors: Chume Fernando C. , Freitas Priscila A.C. , Schiavenin Luisa G. , Pimentel Ana L. , Camargo Joíza Lins 
Published: April 2022

Abstract

Objectives
Guidelines recommend the diagnosis of diabetes should be based on either plasma glucose or glycated hemoglobin (HbA1C) findings. However, lately studies have advocated glycated albumin (GA) as a useful alternative to HbA1c. We conducted a systematic review and meta-analysis to determine the overall diagnostic accuracy of GA for the diagnosis of diabetes.

Content
We searched for articles of GA diabetes diagnostic accuracy that were published up to August 2021. Studies were selected if reported an oral glucose tolerance test as a reference test, measured GA levels by enzymatic methods, and had data necessary for 2 × 2 contingency tables. A bivariate model was used to calculate the pooled estimates.

Summary
This meta-analysis included nine studies, totaling 10,007 individuals. Of those, 3,106 had diabetes. The studies showed substantial heterogeneity caused by a non-threshold effect and reported different GA optimal cut-offs for diagnosing diabetes. The pooled diagnostic odds ratio (DOR) was 15.93 and the area under the curve (AUC) was 0.844, indicating a good level of overall accuracy for the diagnosis of diabetes. The effect of the GA threshold on diagnostic accuracy was reported at 15.0% and 17.1%. The optimal cut-off for diagnosing diabetes with GA was estimated as 17.1% with a pooled sensitivity of 55.1% (95% CI 36.7%–72.2%) and specificity of 94.4% (95% CI 85.3%–97.9%).

Outlook
GA has good diabetes diagnostic accuracy. A GA threshold of 17.1% may be considered optimal for diagnosing diabetes in previously undiagnosed individuals.
A comprehensive comparison between ISAC and ALEX2 multiplex test systems
Authors: Platteel Anouk C.M. , van der Pol Pieter , Murk Jean-Luc , Verbrugge-Bakker Ingrid , Hack-Steemers Marian , Roovers Theo H.W.M. , Heron Michiel 
Published: April 2022

Abstract

Objectives
Diagnosis of type I hypersensitivity is based on anamnesis, provocation as well as blood- and skin testing. Multiplex specific IgE (sIgE) testing enables determination of sIgE antibodies against multiple recombinant or purified natural allergen components. The aim of this study was to evaluate the performance of the novel ALEX2® (Allergy Explorer, ALEX2 test introduced on the market November 2019) multiplex platform and to compare it with the ImmunoCAP ISAC® test system.

Methods
Serum samples of 49 patients, routinely determined with ISAC, were selected based on positive results covering in total most of the 112 ISAC components. Cohen’s kappa, negative percent agreement (NPA), and positive percent agreement (PPA) of ALEX2 data compared to ISAC data (as a non-reference standard) were computed for those allergen components present on both platforms (n=103). Furthermore, in some samples sIgE results against allergen extracts and/or -components tested with either ImmunoCAP® (ThermoFisher) or IMMULITE® (Siemens) were available and compared to ALEX2 results.

Results
The overall agreement between ISAC and ALEX2 common allergen components was 94%. NPA and PPA were respectively 95 and 90%. Kappa values differed for specific allergen groups and varied between 0.60 and 0.92 showing moderate to almost perfect agreement. Of the qualitative discrepancies between ALEX2 and ISAC, 59% were related to weak positive results i.e. results under 1 kUA/L or 1 ISU, respectively.

Conclusions
The method comparison between ISAC and ALEX2 multiplex tests showed a high concordance for those allergen components present on both platforms.
Non-invariant deformations of left-invariant complex structures on compact Lie groups
Authors: Ishida Hiroaki , Kasuya Hisashi 
Published: April 2022

Abstract
We give small deformations of a left-invariant complex structure on each simply connected semisimple compact Lie group of even dimension which are not biholomorphic to any left-invariant (right-invariant) complex structure by using the Kuranishi space.
On such deformed complex manifolds, we prove the Borel–Weil–Bott type theorem, and we compute the cohomology of holomorphic tangent bundles.
The Impact of Social Media on Disaster Volunteerism: Evidence from Hurricane Harvey
Authors: Demiroz Fatih , Akbas Esra 
Published: April 2022

Abstract
Emergent volunteer groups play a significant role during disasters. There is a rich literature on the role of volunteer groups in disasters and disaster volunteerism. However, the rapid proliferation of social media platforms in the last decade made a significant impact on human lives, and disaster volunteerism is no exception. This article argues that there is a need for understanding social media’s impact on disaster volunteerism. Using Harvey as a case, this article analyzes 74 Facebook groups that were created during the storm. The article compares the emergence and lifespan, structure, and function of online volunteer groups to those of volunteer groups before social media. Findings show important distinctions between online groups and those mentioned in the literature. First, online groups are easier to observe and analyze because of the digital traces they leave. Online groups emerge in different phases of disaster (response, early recovery) depending on people’s needs. Their structure can possess elements of hierarchy as opposed to structural characteristics of groups mentioned in the literature. Finally, online groups mostly function as information sharing hubs; however, they also carry out a wide variety of functions, some of which request special attention. The article makes suggestions for future research.
Extracellular matrix in cancer progression and therapy
Authors: He Xiuxiu , Lee Byoungkoo , Jiang Yi 
Published: April 2022

Abstract
The tumor ecosystem with heterogeneous cellular compositions and the tumor microenvironment has increasingly become the focus of cancer research in recent years. The extracellular matrix (ECM), the major component of the tumor microenvironment, and its interactions with the tumor cells and stromal cells have also enjoyed tremendously increased attention. Like the other components of the tumor microenvironment, the ECM in solid tumors differs significantly from that in normal organs and tissues. We review recent studies of the complex roles the tumor ECM plays in cancer progression, from tumor initiation, growth to angiogenesis and invasion. We highlight that the biomolecular, biophysical, and mechanochemical interactions between the ECM and cells not only regulate the steps of cancer progression, but also affect the efficacy of systemic cancer treatment. We further discuss the strategies to target and modify the tumor ECM to improve cancer therapy.
Existence and Stability Results for Coupled Fractional Dynamic System with Impulses over Non-uniform Time Domains
Authors: Kumar Vipin , Malik Muslim 
Published: April 2022

Abstract
In this manuscript, we examine the existence, uniqueness and stability results for a coupled fractional dynamical system with impulsive and initial-boundary (IB) conditions on non-uniform time domains by implying the theory of time scales. Firstly, we find the solution of the consider problem, then we examine the existence and stability results. Mainly, we use the Banach and Leray-Schauder’s alternative type fixed point theorems to establish the main results. At last, we present an example to illustrate the utilization of these analytical outcomes.
Ezekiel’s Nonverbal Responses as Prophetic Message
Authors: Ganzel Tova 
Published: April 2022

Abstract
This article explores the way nonverbal language and gestures in the book of Ezekiel are used to convey the prophetic message. First, they serve as responses to prophetic messages. Second, the prophet’s role as a »model« means that these nonverbal language and gestures add a layer of meaning, often by reflecting a disparity between expected despair and the people’s passivity.
Effect of composition on the Raman response of the Cu2(Fe
x
Zn1−x
)SnS4 and Cu2(Mn
x
Zn1−x
)SnS4 solid solutions
Authors: Suss Nicole , Heppke Eva M. , Avci Fatma D. , Appelt Oona , Efthimiopoulos Ilias 
Published: April 2022

Abstract
We have examined the effect of composition on the Raman-active vibrational response of the Cu2(Fe
x
Zn1−x
)SnS4 and Cu2(Mn
x
Zn1−x
)SnS4 solid solution series at ambient conditions. Based on these results we were able to identify the phase boundaries of the respective kesterite-type and stannite-type structures adopted by these compounds as a function of composition. In the case of Cu2(Fe
x
Zn1−x
)SnS4, our observations correlate very well with earlier reports. For the Cu2(Mn
x
Zn1−x
)SnS4 series, on the other hand, we were able to clearly pinpoint the kesterite↔stannite transition for intermediate compositions for the first time, indicating that Raman spectroscopy can serve as an efficient method for monitoring subtle structural transitions in these systems.
Leveraging EHR Data to Evaluate the Association of Late Recognition of Deterioration With Outcomes
Authors: Mehta Sanjiv D. , Muthu Naveen , Yehya Nadir , Galligan Meghan , Porter Ezra , McGowan Nancy , Papili Kelly , Favatella Dana , Liu Hongyan , Griffis Heather , Bonafide Christopher P. , Sutton Robert M. 
Published: April 2022

OBJECTIVES
Emergency transfers (ETs), deterioration events with late recognition requiring ICU interventions within 1 hour of transfer, are associated with adverse outcomes. We leveraged electronic health record (EHR) data to assess the association between ETs and outcomes. We also evaluated the association between intervention timing (urgency) and outcomes.

METHODS
We conducted a propensity-score-matched study of hospitalized children requiring ICU transfer between 2015 and 2019 at a single institution. The primary exposure was ET, automatically classified using Epic Clarity Data stored in our enterprise data warehouse endotracheal tube in lines/drains/airway flowsheet, vasopressor in medication administration record, and/or ≥60 ml/kg intravenous fluids in intake/output flowsheets recorded within 1 hour of transfer. Urgent intervention was defined as interventions within 12 hours of transfer.

RESULTS
Of 2037 index transfers, 129 (6.3%) met ET criteria. In the propensity-score-matched cohort (127 ET, 374 matched controls), ET was associated with higher in-hospital mortality (13% vs 6.1%; odds ratio, 2.47; 95% confidence interval [95% CI], 1.24–4.9, P = .01), longer ICU length of stay (subdistribution hazard ratio of ICU discharge 0.74; 95% CI, 0.61–0.91, P &lt; .01), and longer posttransfer length of stay (SHR of hospital discharge 0.71; 95% CI, 0.56–0.90, P &lt; .01). Increased intervention urgency was associated with increased mortality risk: 4.1% no intervention, 6.4% urgent intervention, and 10% emergent intervention.

CONCLUSIONS
An EHR measure of deterioration with late recognition is associated with increased mortality and length of stay. Mortality risk increased with intervention urgency. Leveraging EHR automation facilitates generalizability, multicenter collaboratives, and metric consistency.
Prevalence of Adolescent Handgun Carriage: 2002–2019
Authors: Carey Naoka , Coley Rebekah Levine 
Published: April 2022

OBJECTIVES
This study explores the changing prevalence of adolescent handgun carriage, with attention to differences across sociodemographic groups.

METHODS
Data were drawn from repeated cross-sectional, nationally representative surveys conducted annually from 2002 to 2019, the National Survey on Drug Use & Health. The study sample included adolescents aged 12 to 17 (N = 297 055). Logistic regression models estimated the prevalence of past year handgun carriage across cohort and sociodemographic subgroups. Interactions between 4-time cohorts and other variables explored sociodemographic variability in prevalence rates over time.

RESULTS
Handgun carriage increased significantly, particularly among rural, White, and higher-income adolescents. Carriage increased by 41% over cohorts, with predicted prevalence rates increasing from 3.3% in 2002–2006 to 4.6% in 2015–2019. Across cohorts, rural (5.1%), American Indian/Alaskan Native (5.2%), lower-income (&lt;$20 000; 3.9%), male (5.9%), and older (16–17 years old; 4.5%) adolescents were the most likely to report carriage. However, these patterns changed significantly over time, with White and higher-income adolescents (&gt;$75 000) most likely to carry in the most recent cohorts. Predicted carriage rates increased from 3.1% to 5.3% among White adolescents, from 2.6% to 5.1% among higher-income adolescents, and from 4.3% to 6.9% among rural adolescents between the 2002–2006 and 2015–2019 cohorts. Carriage among Black, American Indian/Alaskan Native, and lower-income adolescents decreased.

CONCLUSIONS
Adolescent handgun carriage is increasing, concentrated among particular subgroups of youth, and carriage patterns across sociodemographic groups have changed over time. Programs to address the risk of adolescent gun carriage should be tailored to the specific sociocultural and place-based concerns of diverse adolescents.
Calidad composicional del ensilaje de tres cultivares de maíz (Zea mays) del trópico alto colombiano
Authors: Mancipe-Muñoz Edgar A. , Castillo-Sierra Javier , Vargas-Martínez Juan De J. , Avellaneda-Avellaneda Yesid 
Published: April 2022

Introducción. Elaborar ensilajes de maíz de buena calidad es una estrategia para incrementar la eficiencia de los sistemas de alimentación de rumiantes. Objetivo. Evaluar el efecto de la proporción de mazorcas y el tiempo de sellado sobre la calidad composicional del ensilaje de tres cultivares de maíz en el trópico alto colombiano, cosechados en la fase reproductiva de grano lechoso-pastoso. Materiales y métodos. El experimento se realizó en el año 2017, en Mosquera, Colombia, con los cultivares Simijaca, Medellín y Pionner. Experimento 1, se generaron cuatro proporciones diferentes de mazorca en el ensilado. Experimento 2, la biomasa se ensiló a las 0, 8 o 16 horas de oreo. Se determinó materia seca (MS), proteína cruda, almidón y fibras en detergente neutro (FDN) y ácida (FDA). Se evaluó la dinámica de descenso del pH. Se determinó el efecto de la proporción de mazorcas y el tiempo de oreo sobre la digestibilidad de la MS, MO y FDN solo en el cultivar Simijaca. La calidad composicional y la dinámica del pH se analizaron mediante un diseño completamente al azar con arreglo factorial, mientras la digestibilidad con un diseño completamente al azar. Resultados. El cultivar Medellín presentó menor proporción de mazorca y concentración de almidón (11,9 %) (p<0,05) y mayor contenido de FDN (51,7 %) (p<0,05). El mayor contenido de mazorca aumentó la concentración de almidón, energía y digestibilidad (p<0,05) y disminuyó (p<0,05) el valor del pH final (3,69). El oreo aumentó la MS, la FDN, (p<0,05) y el valor final y la tasa de descenso del pH, pero no cambió la digestibilidad de la MS, MO y FDN. Conclusión. Utilizar ensilaje de maíz con una proporción de mazorca mayor a 66 % y sellar rápido la biomasa de los cultivares Simijaca y Pioneer, mejoró las condiciones de fermentación y calidad composicional.
Variabilidad morfoagronómica en especímenes de papayo silvestre (Carica cubensis Solms) en Cuba
Authors: Rodríguez-Cabello Jesús , González-Vega Maria Esther 
Published: April 2022

Introducción. El papayo es la tercera fruta tropical de mayor importancia a nivel mundial. Sin embargo, en la variedad silvestre, endémica de Cuba, no existen evidencias de estudios para su conservación, cultivo o programas de mejoramiento. Objetivo. Evaluar especímenes de papayo silvestre de la cuenca Almendares-Vento, con el empleo de descriptores morfoagronómicos, para contribuir a la conservación y valorar su potencial productivo y de caracteres de interés para el mejoramiento genético de C. papaya. Materiales y métodos. La investigación se desarrolló entre 2008 y 2018, in situ, en la Cuenca Almendares-Vento, Mayambeque, y condiciones tradicionales de cultivo, en el Instituto Nacional de Ciencias Agrícolas, San José de Las Lajas, Cuba. Las evaluaciones se realizaron mediante dieciséis descriptores morfoagronómicos recomendados para la especie. En el 2016 se colectaron semillas de once plantas para su evaluación individual ex situ. Los descriptores cualitativos se describieron mediante imágenes fotográficas y para los cuantitativos in situ se calcularon los estadígrafos descriptivos de cada una de las variables evaluadas. Para las evaluaciones ex situ se realizó un análisis de componentes principales y un biplot. A cada descriptor se le realizó intervalos de confianza al 95 %. Resultados. In situ la población de papayo silvestre estaba constituida por especímenes que habitaban aislados y distantes unos de otros. En condiciones de cultivo tradicional mostraron variabilidad morfoagronómica en el número de frutos y sus dimensiones, los °Brix y la acidez. Además de su valor ecológico, los caracteres antes mencionados revelaron cualidades potenciales en la identificación de genotipos promisorios, relacionados con el mercado y empleo en el mejoramiento del cultivo. Conclusión. Los frutos presentaron propiedades físicas y bromatológicas que convierten al papayo silvestre en un recurso fitogenético promisorio, para su empleo en el mejoramiento del cultivo y como una alternativa de producción en condiciones tradicionales.
KAJIAN HASIL TANGKAPAN RAJUNGAN DI PANTAI UTARA DAN PANTAI SELATAN JAWA BARAT
Authors: - Suhernalis , Rahman Abdul 
Published: April 2022

Rajungan (Portunus pelagicus) merupakan salah satu crustasea hasil laut yang mempunyai nilai ekonomis penting. Namun banyaknya penangkapan yang tidak sesuai mengakibatkan sumberdaya rajungan menurun. Penelitian ini dilakukan di Perairan Provinsi Jawa Barat sejak bulan September hingga Oktober 2018. Tujuan penelitian ini adalah untuk mengetahui adanya growth overfishing rajungan (Portunus pelagicus) yang meliputi beberapa aspek biologi seperti lebar-berat rajungan, sex ratio, TKG (Tingkat Kematangan Gonad), ukuran pertama kali tertangkap (Lc), ukuran pertama kali matang gonad (Lm) dan upaya pengelolaan rajungan. Metode yang digunakan dalam penelitian yaitu metode survey dan metode Analisis PSA. Hasil penelitian sementara menunjukkan bahwa hubungan lebar-berat bersifat allometrik negatif. Perbandingan jantan dan betina menunjukan kondisi tidak seimbang. TKG yang dominan adalah TKG III. Nilai Lc = Jantan 7,51 cm; Betina 8,36 cm dan nilai Lm = Jantan 7,30 cm; Betina 6,40 cm, dapat diketahui populasi rajungan jantan lebih cepat mengalami penurunan dibandingkan betina. Berdasarkan analisis PSA, rajungan (Portunus pelagicus) yang ada di Perairan Jawa Barat berada di tingkat kerentanan rendah dan produktivitas rendah.
PENGOLAHAN BANDENG PRESTO DI UKM MANDALA PRESTO, SUKARAJA, KAB. BOGOR - JAWA BARAT
Authors: Salampessy Randi B.S 
Published: April 2022

ABSTRAKPengolahan bandeng dengan cara presto menjadikan duri ikan bandeng lunak dan memudahkanuntuk mengkonsumsinya. Penelitian ini bertujuan untuk mengetahui alur proses produksi bandeng presto, mutu organoleptik , sensori bahan baku dan produk akhir, penerapan rantai dingin atau suhu produk, air serta proses pengolahan, rendemen produk akhir serta penerapan sanitasi dan hygiene . Pelaksanaan penelitian pada tanggal 1 Maret 2021 sampai dengan 14 April 2021. Tempat pelaksanaan berlokasi di UKM Mandala Presto, Kecamatan Sukaraja, Kabupaten Bogor – Jawa Barat. Metode analisis data menggunakan metode deskriptif dan komparatif. Hasil penelitian yaitu penerimaan bahan baku, pelelehan (thawing) dan penyiangan dengan pembelahan, perendaman dalam larutan garam, perendaman bumbu, penyusunan ikan pada wadah pemasakan, pemasakan tanpa tekanan tinggi, pendinginan dengan pemberian bumbu kuning goreng oles serta pengemasan dan pelabelan. Penerapan suhu dingin selama proses pengolahan belum diterapkan secara baik dan benar . Mutu bahan baku dan produk akhir telah memenuhi SNI, dengan nilai organoleptik rata-rata 8, baik sebelum maupun sesudah dilelehkan. Nilai mutu sensorik bandeng presto yaitu kenampakan 7; bau 7,5; rasa 8 ; tekstur 7 dan kapang 9. Rendemen yang diperoleh produk rata-rata 77,24%. Teknik sanitasi dan higiene belum diterapkan secara baik dan benar.KATA KUNCI : Bandeng presto; proses; mutu sensori; rendemen; sanitasi