bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accuracy Decay Mechanism of Ball Screw in CNC Machine Tools for Mixed Sliding-rolling Motion under Non-constant Operating Conditions
Authors: Qi Baobao , Zhao Jiajia , Chen Chuanhai , Song Xianchun , Jiang Hongkui 
Published: May 2022

Abstract
The ball screw (BS) has become an indispensable key functional component in many fields, such as CNC machine tools, precision transmission system and special service requirements. Its accuracy reliability is a key performance in many application fields. There is a phenomenon of mixed slip-roll motion during the BS operation, however, both non-constant working conditions and mixed sliding-rolling motion mode affect the its accuracy decay. In this paper, the modeling method of accuracy decay for mixed sliding-rolling motion behavior is established under non-constant operating conditions. The accuracy reliability of the BS is analyzed under single non-constant operation condition or multiple non-constant operating conditions, and the accuracy decay is predicted though modeling method proposed. In addition, the experimental analysis of the BS accuracy degradation is carried out under three different amplitudes of AL (non-constant axial load), FR (non-constant feed rate) and AL + FR combination conditions. The average value of the accuracy loss relative error between theoretical model and experimental test results is smaller than that under pure sliding motion. It shows that the accuracy decay analysis model established is beneficial to predict the BS accuracy reliability.
Artificial Intelligence-based Point-of-care Lung Ultrasound for Screening COVID-19 Pneumoniae: Comparison with CT Scans
Authors: Kuroda Yumi , Kaneko Tomohiro , Yoshikawa Hitomi , Uchiyama Saori , Nagata Yuichi , Matsushita Yasushi , Hiki Makoto , Minamino Tohru , Takahashi Kazuhisa , Daida Hiroyuki , Kagiyama Nobuyuki 
Published: May 2022

Abstract
Background: Although lung ultrasound has been reported to be a portable, cost-effective, and accurate method to detect pneumonia, it has not been widely used because of the difficulty in its interpretation. Here, we aimed to investigate the effectiveness of a novel artificial intelligence-based automated pneumonia detection method using point-of-care lung ultrasound (AI-POCUS) for the coronavirus disease 2019 (COVID-19).Methods: We enrolled consecutive patients admitted with COVID-19 who underwent computed tomography (CT) in August and September 2021. A 12-zone AI-POCUS was performed by a novice observer using a pocket-size device within 24 h of the CT scan. Fifteen control subjects were also scanned. Additionally, the accuracy of the simplified 8-zone scan excluding the dorsal chest, was assessed. More than three B-lines detected in one lung zone were considered zone-level positive, and the presence of positive AI-POCUS in any lung zone was considered patient-level positive.Results: A total of 577 lung zones from 56 subjects (59.4 ± 14.8 years, 23% female) were evaluated using AI-POCUS. The mean number of days from disease onset was 9, and 14% of patients were under mechanical ventilation. The patient-level accuracy of 12-zone AI-POCUS for detecting CT-validated pneumonia was 94.5%, sensitivity was 92.3%, and specificity was 100%. When simplified with 8-zone scan, the accuracy, sensitivity, and sensitivity were 83.9%, 77.5%, and 100%, respectively. The zone-level accuracy, sensitivity, and specificity of AI-POCUS were 65.3 %, 37.2%, and 97.8 %, respectively.Interpretation: AI-POCUS using the novel pocket-size ultrasound system showed excellent agreement with CT-validated COVID-19 pneumonia, even when used by a novice observer.
Influence of rheological properties and microstructure of microemulsions on the kinetic release of bioactive compounds
Authors: Cortés Noelia Mori , Montoto Sebastián Scioli , Ruiz María Esperanza , Califano Alicia , Lorenzo Gabriel 
Published: May 2022

Abstract
Microemulsions (ME) are one of the most effective ways to incorporate lipophilic active compounds into water-based food matrices. Great stability, colloidal domain droplets, and optical isotropy are some of the ME advantages. The present work analyzes the influence of rheological behavior and microstructural characteristics of food microemulsions on the release rate of lipophilic vitamins. A fluid ME was compared to a ME with higher dispersed phase content and a bicontinuous structure (gel-ME). Additionally, carboxymethyl cellulose (CMC) was added to fluid ME (3.5 and 10 g/100g), obtaining systems with different viscosity and microstructure. All ME were characterized using FTIR, rheological analysis, and TEM microscopy. Those systems with similar zero-shear viscosity showed significantly different viscoelastic behavior; gel-ME behaved like a concentrated suspension of macromolecules but with the largest plateau modulus. Microemulsions with CMC exhibited a viscoelastic solid type with G’ > G’’. Mechanical spectra were satisfactorily fitted with Generalized Maxwell model and the relaxation time spectra were determined. Kinetic release of vitamins E and D was studied and modeled at 37°C. Fluid and gel-ME reached higher percentages of release in a very fast manner, while CMC systems showed a matrix-driven nature of the release, in agreement with the relaxation time behavior determined from rheological experiments.
The estimate of the required amount of water on the growth of five species of Paulownia at the first year of cultivation in a Central Europe
Authors: Kadlec Jiří , Novosadová Kateřina , Pokorný Radek 
Published: May 2022

Abstract
Needed precipitation or supplied water is not known for mostly hybrids. Therefore, we chose one species Paulownia tomentosa and four hybrids - P. bellissia®, P. Clon in vitro 112®, P. Shan Tong and P. Hybrid 9502. We found out how three types of watering affect their height and thickness increment, amount of leaf biomass and leaf area and if the reaction of plants of these species/hybrids to the amount of water is different. We planted 30 plants of each species/hybrids into plant pots under a shelter. At the end of the growing season, we measured the total heights of the plants, the lengths of the current-year shoots, the stem thicknesses of the current-year shoots, and the distances of the ends of the leaves furthest from the stem in the directions of all four cardinal points. We determined leaves area and their weighed (calculated the projection area of the crown and the leaf area index). Our results showed that, generally, the mean precipitation 50 mm per month in vegetation season seems to be insufficient for optimal growth of Paulownia plants in the first years after planting. Depending on the species, Paulownia Shan Tong seems to grow better under 100 mm per month in vegetation season; Paulownia tomentosa seems to grow better under 150 mm (and more) per month in vegetation season; and the plants of Paulownia Hybrid 9502, P. bellissia® and P. Clon in vitro 112® did not achieve optimal growth (values), no matter which type of watering we used.
Identification of stromal microenvironment characteristics and key molecular mining in pancreatic cancer
Authors: Ji Hongchen , Zhang Qiong , Wang Xiangxu , Li Junjie , Wang Xiaowen , Pan Wei , Zhang Zhuochao , Ma Ben , Zhang Hong-Mei 
Published: May 2022

Abstract
Purpose
Pancreatic cancer is one of the deadliest cancers worldwide. The extracellular matrix (ECM) microenvironment affects the drug sensitivity and prognosis of pancreatic cancer patients. This study constructed an 8-genes pancreatic ECM scoring (PECMS) model, to classify the ECM features of pancreatic cancer, analyze the impact of ECM features on survival and drug sensitivity, and mine key molecules that influence ECM features in pancreatic cancer.
Methods
GSVA score calculation and clustering were performed in TCGA-PAAD patients. Lasso regression was used to construct the PECMS model. The association between PECMS and patient survival was analyzed and validated in the CPTAC-3 dataset of TCGA and our single-center retrospective cohort. The relationships between PECMS and features of the matrix microenvironment were analyzed. Finally, PECMS feature genes were screened and verified in pancreatic cancer specimens to select key genes associated with the ECM microenvironment.
Result
The survival of the PECMS-high group was significantly worse. The PECMS-high group showed higher oxidative stress levels, lower levels of antigen presentation- and MHC-I molecule-related pathways, and less immune effector cell infiltration. Data from IMvigor-210 cohort suggested that PECMS-low group patients were more sensitive to immune checkpoint blockers. The PECMS score was negatively correlated with chemotherapy drug sensitivity. The negative association of PECMS with survival and drug sensitivity was validated in our retrospective cohort. KLHL32 expression predicted lower oxidative stress level and more immune cells infiltrate in pancreatic cancer.
Conclusion
PECMS is an effective predictor of prognosis and drug sensitivity in pancreatic cancer patients. KLHL32 may play an important role in the construction of ECM, and the mechanism is worth further study.
Coastal scenic assessment in northern France: a useful tool for characterization and conservation of most attractive sites following the Conservatoire du littoral management approach
Authors: Mooser Alexis , Anfuso Giorgio , Herbert Vincent , Williams Allan Thomas , Aucelli Pietro P.C 
Published: May 2022

Abstract
“Buy to protect”: this may be the Conservatoire du Littoral philosophy. Since 1975, this unique public French institution endeavours to acquire vulnerable and threatened coastal areas of great natural relevance to ensure their permanent and sound management/protection by establishing conventions with local authorities. This paper is focused on (i) the research of remarkable attractive natural sites not (or only slightly) affected by human intrusions, (ii) the analysis of the Conservatoire policies related to landscape issues and (iii) the proposal of judicious measures to assess/maintain/enhance/monitor landscape quality. For such proposals, the Coastal Scenic Evaluation System (CSES) method was in situ applied along the northern French coast, from Belgium to the Seine estuary. This area, shaped in a macrotidal environment, was chosen as it exhibits a wide variety of scenery composed of majestic dunes complexes, estuaries, bays and impressive cliff formations, alongside a strong cultural heritage. It also includes some world-renowned sites such as Les Deux Caps (Gris-Nez and Blanc-Nez), the Somme Bay and the cliffs of Étretat. CSES is a strong accurate indicator of scenic quality based on 26 physical and human parameters, and fuzzy-logic mathematics to overcome subjectivity and quantify uncertainties. As a result, an evaluation index (D) is obtained, enabling to classify sites into five distinct classes, from Class I (outstanding quality) to Class V (very poor quality). In this paper, 16 sectors respectively located along the Côte d’Opale (8), Côte Picarde (4) and Côte d’Albâtre (4) were selected after a long process of field testing. Seven were included in Class I, five in Class II and four in Class III. Finally, suggestions were made to complete the remarkable labour done by the Conservatoire.
Sustainable Fish Feeds: Optimization of Levels of Inorganic Fertilizers for Mass Production of Oocystis Sp. For Climate Smart Aquaculture
Authors: Mukoma Marvin Gaye , Odour Steve Omondi , Otachi Elick Onyango 
Published: May 2022

Abstract
Use of microalgae as source of food in aquaculture production is gaining recognition due to their rapid growth rate that promises high biomass generation within a short time. The challenge faced is getting good and inexpensive nutrients source to be used in mass production of the required microalgae. This study investigated the effect of different nutrient combination in influencing the growth rate of the of the green algae Oocystis sp. which has been indentified as possible protein source for the raising of Orechromis niloticus fingerlings for fish farming. Modified Bolds 3N Medium and commercial agricultural fertilisers (urea, NPK and DAP) media were compared to establish the appropriate combination that would result into high biomass generation but at the lowest cost possible. The Modified Bold 3N Medium acted as the control, at a cost of 11.28 KSh per litre, the other media were derived from urea, NPK and DAP (varying the ratio of each) at a cost of treatment 1 (0.14 KSh per litre), treatment 2 (0.18 KSh per litre) and treatment 3 (0.22 KSh per litre). The algae was cultured for five weeks with samples taken daily for biomass analyses using chloropyhll-a concentration as the surrogate for Oocystis sp. biomass for 30 days, from each treatment was determined. The growth rate, doubling time, and divisions per day were then estimated based on this chlorophyll-a concentration. The results showed that the mean concentrations of chlorophyll-a in treatment 1 was highest (7.715 ± 0.667 µg/ml) while treatment 3 (6.441 ± 0.555 µg/ml) had the least. There was no significant differences in the mean concentrations of chlorophyll-a in the four treatments (Kruskal-Wallis H test: P > 0.05). The chlorophyll-a concentration varied significantly in each treatment with time (Kruskal-Wallis H test: P < 0.001). There was no significant difference in the growth rate (Kruskal-Wallis H test: P > 0.05), divisions per day (Kruskal-Wallis H test: P > 0.05), and doubling time (Kruskal-Wallis H test: P > 0.05) from the different treatments. The results of this study showed that inorganic fertilizers can be used as cost-effective media in the mass scale culture of Oocystis sp.
Levetiracetam modulates EEG Microstates in Temporal Lobe Epilepsy
Authors: Ricci Lorenzo , Croce Pierpaolo , Pulitano Patrizia , Boscarino Marilisa , Zappasodi Filippo , Narducci Flavia , Lanzone Jacopo , Sancetta Biagio , Mecarelli Oriano , Lazzaro Vincenzo Di , Tombini Mario , Assenza Giovanni 
Published: May 2022

Abstract
Objective: To determine the effects of Levetiracetam (LEV) therapy using EEG microstates analysis in a population of newly diagnosed Temporal Lobe Epilepsy (TLE) patients. We hypothesized that the impact of LEV therapy on the electrical activity of the brain can be globally explored using EEG microstates.Methods: Twenty-seven patients with TLE were examined. We performed resting-state microstate EEG analysis and compared microstate metrics between the EEG performed at baseline (EEGpre) and after three months of LEV therapy (EEGpost). Results: The microstates A, B, C and D emerged as the most stable. LEV induced a reduction of microstate B and D mean duration and occurrence per second (p<0.01). Additionally, LEV treatment increased the directional predominance of microstate A to C and microstate B to D (p=0.01).Conclusions: LEV treatment induces a modulation of resting-state EEG microstates in newly diagnosed TLE patients. Microstates analysis has the potential to identify a neurophysiological indicator of LEV therapeutic activity. This study of EEG microstates in people with epilepsy opens an interesting path to identify potential LEV activity biomarkers that may involve increased neuronal inhibition of the epileptic network.
First assessment on the influence of wind farms and high-voltage networks on Ruddy-headed goose migration in Patagonia, Argentina
Authors: Pedrana Julieta , Gorosábel Antonella , Pütz Klemens , Bernad Lucía 
Published: May 2022

Abstract
Ruddy-headed goose Chloephaga rubidiceps has a migratory population that overwinters mainly in the Pampas region, Argentina, and breeds in Southern Patagonia. This population has decreased considerably, with less than 800 individuals remaining to date. We conducted the first assessment on the influence of environmental and anthropogenic impact (wind farms and high voltage networks) variables on Ruddy-headed goose migration pathways across the Patagonian coast by applying kernel density analyses and statistical procedures on satellite tracking data obtained from six Ruddy-headed geese during their migration pathways between 2015 and 2018. Five core distribution areas were identified during migration. During autumn migration, core areas were associated with high primary productivity and low elevation areas, while during spring migration they were located in the proximity of watercourses and waterbodies. We found that around 30% of the grid cells included in the high-density areas were located in the influence area of high voltage networks during both migrations. While 33% of the grid cells included in the high-density areas were in the influence zone of wind farms during autumn migration; while this applied to only 13% during spring migration. We highlight areas of high risk along the distributional range of the species where large-scale patterns of collision mortality are likely to occur and mitigation measures should be prioritized. We suggest proactive measures that could mitigate future collisions with energy infrastructure because, given their threatened status, a few deaths may have a large effect on the small remnant population.
Genetic analysis of Torque teno canis virus identified in Korea
Authors: Kim Da-Yoon , Ahn Hee-Seop , Han Sang-Hoon , Go Hyeon-Jeong , Kim Dong-Hwi , Kim Jae-Hyeong , Lee Joong-Bok , Park Seung-Yong , Song Chang-Seon , Lee Sang-Won , Choi In-Soo 
Published: May 2022

Abstract
The Torque teno canis virus (TTCaV) is a 2.8 kb-long circular single-stranded DNA virus that has been reported to cause infections in dogs. In this study, 135 fecal samples of dogs were collected in South Korea to determine TTCaV infection status. When the prevalence was determined by polymerase chain reaction (PCR), 17 of 135 (12.6%) patients tested positive for TTCaV. Three full genetic sequences (GenBank IDs: MZ503910, MZ503911, and MZ503912) and 12 ORF1 sequences (GenBank IDs: MZ503913–MZ503924) were obtained from the 17 fecal specimens. Sequence identity, phylogenetic, similarity plot, and recombination analyses were performed using the three full TTCaV genomes. One (MZ503912) of the three TTCaVs was found to be a recombinant virus when analyzed with their full genomic sequences. The recombinant virus might have been generated between one TTCaV strain, KX827768, discovered in China, and MZ503910, which was identified in Korea. This is the first report to determine the prevalence, genetic variation, and recombination of TTCaVs in dogs in Korea. Our study demonstrated that TTCaV exists in Korea. Further studies are needed on the pathogenesis of TTCaV in dogs.
Does increase in women's empowerment and socio-economic conditions affect uptake of breast cancer screening? Findings from NFHS (5), India
Authors: Patil Priti , Sarang Bhakti , Bhandarkar Prashant , Ghoshal Rakhi , Roy Nobhojit , Gadgil Anita 
Published: May 2022

Abstract
Background: Breast cancer screening results in early recovery, good prognosis and improving the overall survival due to disease. However, proportion of women undergoing breast cancer screening are minimal and their participation get influenced due to low socio-economic and women empowerment status (SES and WES). This study explores the relationship of SES and WES with the breast cancer screening uptakes in the states and union territories of India using demographic health survey.Methods: We used secondary data based on the National Family Health Survey (NFHS) state level factsheet for this study. SES and WES were considered as independent variables and breast cancer screening uptakes as dependent variable. Dimension indices based composite scores were calculated for this purpose. Spearman’s rank correlation coefficient was used to find the association between the SES and WES with breast cancer screening uptake. The determinants of breast cancer screening were obtained using a simple linear regression model using the DI values of each indicator.Results: We found breast cancer screening gets influenced by the SES and WES. State level indicators shows that spearman’s rank correlation coefficient of breast cancer screening is moderately positive with socio-economic (0.336) and women empowerment (0.378) status. The highest screening uptake seen in Tamilnadu and lowest in Chandigarh. Women literacy rate and women having self-operated bank account found the significantly associated with the BC screening. Conclusion: This study underlines that improving SES and WES may influence the breast cancer screening uptake. However, not all the components of SES and WES considered in the study are equally influential. More research is needed for the states with relatively higher WES and SES, but do not screen adequately.
Correlation between Earnings Management and Financial Distress among Selected Firms in Kenya
Authors: Kamau Charles Guandaru , Ali Abdulkadir Banafa , Kariuki Samuel Nduati 
Published: May 2022

Abstract
This paper evaluates the link between earnings management and financial distress among listed firms in Kenya. The assessment compares the modified Jones score, which is commonly used to measure discretionary accruals, with Altman’s Z score, which measures the degree of financial distress. The earnings management and financial distress. The selected firms under this study are known to be financially distressed as per the publicly available information. The hypothesis tests express whether a correlation exists between earnings management and financial distress. The result also highlights the level of significance of the effect of earnings management on financial distress.
Dendrobium officinale Endophytes May Colonize the Intestinal Tract and Regulate Gut Microbiota in Mice
Authors: Chen Wenhua , Yu Lilong , Zhu Bo , Qin Luping 
Published: May 2022

Abstract
Dendrobium officinale is a traditional Chinese medicine for treating gastrointestinal diseases by nourishing “Yin” and thickening stomach lining. To study whether D. officinale endophytes can colonize the intestinal tract and regulate gut microbiota in mice, we used hot-pressure and 60Co-γ radiation to eliminate D. officinale endophytes from its juice. Then, high-throughput ITS1-ITS2 rDNA and 16S rRNA gene amplicons were sequenced to analyze the microbial community of D. officinale endophytes and fecal samples of mice after administration of fresh D. officinale juice. Sterilization of D. officinale juice by autoclaving for 40 min (ASDO40) could more effectively eliminate the D. officinale endophytes and decrease their interference on the gut microbiota. D. officinale juice could increase beneficial gut microbiota and metabolites including short-chain fatty acids. D. officinale endophytes Pseudomonas mosselii, Trichocladium asperum, Titata maxilliformis, Clonostachys epichloe, and Rhodotorula babjevae could colonize the intestinal tract of mice and modulate gut microbiota after oral administration of the juice for 28 days. Thus, the regulatory effect of D. officinale juice on gut microbiota was observed, which provides a basis for inferring that D. officinale endophytes might colonize the intestinal tract and participate in regulating gut microbiota to treat diseases. Thus, this study further provides a new approach for the treatment of diseases by colonizing plant endophytes in the intestinal tract and regulating gut microbiota.