bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitoring spatiotemporal soil moisture changes in the subsurface of forest sites using electrical resistivity tomography (ERT)
Authors: Fäth Julian , Kunz Julius , Kneisel Christof 
Published: June 2022

AbstractThe effects of drought on tree mortality at forest stands are not completely understood. For assessing their water supply, knowledge of the small-scale distribution of soil moisture as well as its temporal changes is a key issue in an era of climate change. However, traditional methods like taking soil samples or installing data loggers solely collect parameters of a single point or of a small soil volume. Electrical resistivity tomography (ERT) is a suitable method for monitoring soil moisture changes and has rarely been used in forests. This method was applied at two forest sites in Bavaria, Germany to obtain high-resolution data of temporal soil moisture variations. Geoelectrical measurements (2D and 3D) were conducted at both sites over several years (2015–2018/2020) and compared with soil moisture data (matric potential or volumetric water content) for the monitoring plots. The greatest variations in resistivity values that highly correlate with soil moisture data were found in the main rooting zone. Using the ERT data, temporal trends could be tracked in several dimensions, such as the interannual increase in the depth of influence from drought events and their duration, as well as rising resistivity values going along with decreasing soil moisture. The results reveal that resistivity changes are a good proxy for seasonal and interannual soil moisture variations. Therefore, 2D- and 3D-ERT are recommended as comparatively non-laborious methods for small-spatial scale monitoring of soil moisture changes in the main rooting zone and the underlying subsurface of forested sites. Higher spatial and temporal resolution allows a better understanding of the water supply for trees, especially in times of drought.
A-Isometries and Hilbert-A-Modules Over Product Domains
Authors: Didas Michael 
Published: June 2022

AbstractFor a compact set$$K \subset {\mathbb {C}}^n$$K⊂Cn, let$$A \subset C(K)$$A⊂C(K)be a function algebra containing the polynomials$${\mathbb {C}}[z_1,\cdots ,z_n ]$$C[z1,⋯,zn]. Assuming that a certain regularity condition holds forA, we prove a commutant-lifting theorem forA-isometries that contains the known results for isometric subnormal tuples in its different variants as special cases, e.g., Mlak (Studia Math. 43(3): 219–233, 1972) and Athavale (J. Oper. Theory 23(2): 339–350, 1990; Rocky Mt. J. Math. 48(1): 2018; Complex Anal. Oper. Theory 2(3): 417–428, 2008; New York J. Math. 25: 934–948, 2019). In the context of Hilbert-A-modules, our result implies the existence of an extension map "Equation missing"for hypo-Shilov-modules "Equation missing"$$(i=1,2)$$(i=1,2). By standard arguments, we obtain an identification "Equation missing"where "Equation missing"is the minimal$$C(\partial _A)$$C(∂A)-extension of "Equation missing"$$(i=1,2)$$(i=1,2), provided that "Equation missing"is projective and "Equation missing"is pure. Using embedding techniques, we show that these results apply in particular to the domain algebra$$A=A(D)=C({\overline{D}})\cap {\mathcal {O}}(D)$$A=A(D)=C(D¯)∩O(D)over a product domain$$D = D_1 \times \cdots \times D_k \subset {\mathbb {C}}^n$$D=D1×⋯×Dk⊂Cnwhere each factor$$D_i$$Diis either a smoothly bounded, strictly pseudoconvex domain or a bounded symmetric and circled domain in some$${\mathbb {C}}^{d_i}$$Cdi($$1\le i \le k$$1≤i≤k). This extends known results from the ball and polydisc-case, Guo (Studia Math. 135(1): 1–12, 1999) and Chen and Guo (J. Oper. Theory 43: 69–81, 2000).
Strategic agility, openness and performance: a mixed method comparative analysis of firms operating in developed and emerging markets
Authors: Vrontis Demetris , Belas Jaroslav , Thrassou Alkis , Santoro Gabriele , Christofi Michael 
Published: June 2022

AbstractThis research delineates the relationship between strategic agility and performance, and proposes openness as a requisite means to fostering agility and enhancing performance. Methodologically, the research follows the pragmatist paradigm through a mixed-method research design, incorporating three separate studies. These comprise a CEO-based survey on foreign firms operating in emerging markets, a CEO-based survey on firms operating in developed countries, and CEO interviews, all of which are complimented by auxiliary instruments of secondary data and an expert panel. The research finds that strategic agility is vital for firms’ performance in both developed and developing markets. Moreover, we found that while search depth amplifies the above relationship in both contexts, search breadth does it only in the context of foreign firms operating in emerging markets. The value of these findings stems from their elucidation of the role of strategic agility in emerging markets and its comparison to that of firms operating in developed countries; their insights into strategic agility’s relationship with openness; their schematic culmination into a systemically and contextually depicted framework; and their prescriptive managerial implications.
Immune Checkpoint Inhibitors and Chemoradiation for Limited-Stage Small Cell Lung Cancer
Authors: Schlick Brian , Shields Misty Dawn , Marin-Acevedo Julian A. , Patel Ishika , Pellini Bruna 
Published: June 2022

Opinion statementLimited-stage small cell lung cancer (LS-SCLC) is a potentially curable disease. However, most patients develop disease relapse shortly after definitive treatment. The landmark trials IMpower133 and CASPIAN demonstrated a survival benefit with the addition of immunotherapy to first-line platinum/etoposide for extensive-stage small cell lung cancer. Therefore, it is critical to determine whether advancements in overall survival with immunotherapy can be translated earlier into the treatment paradigm for LS-SCLC. Decades of robust preclinical research into the synergism of radiation therapy and immunotherapy set the stage for the combination of these treatment modalities. Recently published data suggests tolerability of single agent immunotherapy concurrent with chemoradiation in LS-SCLC, along with promising efficacy. However, combination immunotherapy in the consolidation setting appears too toxic, although this may be reflective of the dosing schedule rather than inherent to any combination immune checkpoint blockade. Here, we review underlying mechanisms of synergy with the combination of radiation and immunotherapy, the safety and efficacy of respective treatment modalities, and the ongoing trials that are exploring novel therapeutic approaches for LS-SCLC. Pivotal trials in LS-SCLC are ongoing and anticipated to aid in understanding efficacy and safety of immunotherapy with concurrent platinum-based chemoradiotherapy.
Renin–Angiotensin–Aldosterone Inhibitors and COVID-19 Infection
Authors: Tsampasian Vasiliki , Corballis Natasha , Vassiliou Vassilios S. 
Published: June 2022

AbstractPurpose of ReviewThis review summarises the literature data and provides an overview of the role and impact of the use of renin–angiotensin–aldosterone system (RAAS) inhibitors in patients with coronavirus disease 2019 (COVID-19) infection.Recent FindingsThe angiotensin-converting enzyme 2 (ACE2) has a key role in the regulation of the RAAS pathway, downregulating angiotensin II and attenuating inflammation, vasoconstriction and oxidative stress. Additionally, it plays an instrumental part in COVID-19 infection as it facilitates the cell entry of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and enables its replication. The use and role of RAAS inhibitors therefore during the COVID-19 pandemic have been intensively investigated.SummaryAlthough it was initially assumed that RAAS inhibitors may relate to worse clinical outcomes and severe disease, data from large studies and meta-analyses demonstrated that they do not have an adverse impact on clinical outcomes or prognosis. On the contrary, some experimental and retrospective observational cohort studies showed a potential protective mechanism, although this effect remains to be seen in large clinical trials.
Learning analytics: state of the art
Authors: Hernández-de-Menéndez Marcela , Morales-Menendez Ruben , Escobar Carlos A. , Ramírez Mendoza Ricardo A. 
Published: June 2022

AbstractLearning Analyticsis a field that measures, analyses, and reports data about students and their contexts to understand/improve learning and the place in which it occurs. Educational institutions have different motivations to useLearning Analytics. Some want to improve students' outcomes or optimize their educational technology and reduce the dropout rate and others. This concept is presented with practical experiences that have been acquired and validated by 16 institutions. Besides, an analysis of the results, challenges, and expectations was performed. It was found that the majority of initiatives useLearning Analyticsto improve retention of students; few are focused merely on improving the teaching/learning process or academic issues. The organizations invest their resources in acquiringLearning Analyticssoftware; however, most universities develop their technology. The technology helps organizations be preventive and not reactive as various models determine students at risk of failing. This information allows them to make suitable interventions, which increases the success of the initiative.CoViD19pandemic is also put in context in this research;Learning Analyticscould be a great approach to help the educational community adapt effectively to the new forms of educational delivery. Based on an exhaustive bibliographic review, various educational projects and experiences were analyzed, presenting an overview detailing applications, results, and potentialities and opportunities, hoping that this article will be a useful reference for researchers and faculty to exploitLearning Analyticseducation.
Inflammatory Modulation of miR-155 Inhibits Doxorubicin-Induced Testicular Dysfunction via SIRT1/FOXO1 Pathway: Insight into the Role of Acacetin and Bacillus cereus Protease
Authors: Anwar Hend Mohamed , Hamad Sherin Ramadan , Salem Gad Elsayed Mohamed , Soliman Rania Hassan Mohamed , Elbaz Eman Maher 
Published: June 2022

Abstract
Doxorubicin (DOX) is a chemotherapeutic agent that can disrupt testicular function leading to male infertility. This study examined the protective role of natural flavone, acacetin (ACA), and a protease of Bacillus cereus bacteria (B. cereus) as well as the potential role of miR-155/SIRT1/FOXO1 network in DOX-induced testicular injury. Twenty-four male Wistar rats were randomly allocated into four groups and treated as follows: Control, DOX (1 mg/kg, i.p) every other day for 21 days with a total dose equal to 10 mg/kg throughout the experiment, and pre-treated groups that received ACA (5 mg/kg/day, p.o) or B. cereus protease (36 mg/kg/day, p.o) for a week prior to DOX administration. DOX challenge reduced the testis weight coefficient, serum testosterone, and testicular 17β-hydroxysteroid dehydrogenase (17β-HSD). DOX caused a significant increase in testicular oxidative stress, inflammatory, and apoptotic markers. Aberrant testicular miR-34c, a germ-specific miRNA, and miR-155 expressions were observed, along with decreased protein expression of sirtuin1 (SIRT1) dependent forkhead box 1 (FOXO1) acetylation which induces apoptosis. Besides, abnormal histopathological architecture and a marked reduction in the testicular expression of proliferating cell nuclear antigen (PCNA) were observed. ACA or protease administration significantly improved the histopathological and immunohistochemical pictures compared with DOX alone and renovated testicular functions. Interestingly, treatment with protease was more significant than treatment with ACA in ameliorating DOX-induced testicular injury. Taken together, this study reveals the prophylactic role of these two regimens on male fertility by exhibiting antioxidant, anti-inflammatory, and anti-apoptotic effects against DOX-elicited testicular damage, possibly via modulating miR-155/SIRT1/FOXO1 network.
Graphical abstract
Current status of human adenovirus infection in China
Authors: Mao Nai-Ying , Zhu Zhen , Zhang Yan , Xu Wen-Bo 
Published: June 2022

Abstract
Background
Outbreaks of severe, acute hepatitis among children have recently attracted global attention. The pathogen causing the outbreak remains unknown, but there is growing evidence that it may be associated with human adenovirus (HAdV).

Data sources
A review of adenovirus-related clinical studies, epidemiological studies, etiological studies, and case reports was conducted by reviewers independently.

Results
HAdV can cause a wide variety of clinical symptoms. In the Mainland of China, HAdV infection accounts for 5.8%–13% of patients with acute respiratory infections, and these infections are mainly caused by species B, C, and E of HAdV. For acute conjunctivitis, 39.8%–74.9% of sporadic cases were infected by B and D species of HAdV. Outbreaks of keratoconjunctivitis and pharyngoconjunctival fever related to HAdV infection could be found throughout the country. In pediatric patients with acute gastroenteritis, HAdV-41 was the predominant HAdV type, followed by HAdV species B and C. Several types of HAdV, including HAdV-5, HAdV-7, HAdV-1, and HAdV-2, have previously been reported as potential pathogens associated with HAdV hepatitis in immunocompromised patients. However, few HAdV-related hepatitis cases have been reported in China to date.

Conclusions
There are no systematic surveillance and clinical studies on HAdV hepatitis in China. Therefore, it is imperative to establish a nationwide HAdV virological surveillance system to collect relevant clinical, epidemiological and virological surveillance data and risk factor information as soon as possible to assess the potential risk of HAdV hepatitis among children.
Analysis of Biowaste-Based Materials in the Construction Sector: Evaluation of Thermal Behaviour and Life Cycle Assessment (LCA)
Authors: Vilaboa Díaz Andrés , Francisco López Ahinara , Bello Bugallo Pastora M. 
Published: June 2022

AbstractThe objective of the work is to evaluate the thermal behaviour and the environmental impact of selected building biowaste-based materials, mainly biomass from agrowaste. An evaluation of the state of the art of the materials used from waste or biomass in the construction of buildings is carried out. The selected building materials are based on data availability: hemp concrete, isotex, bricks with olive core flour (OCF), bricks with wheat straw (WS). Subsequently, thermal behaviour is evaluated as a function of decrement factor, time lag and as an application in the thermal envelope of a building. Finally, a life cycle assessment of each material is carried out, including the calculation of the following indicators: non-renewable energy, cumulative energy demand and global warming potential. Hemp concrete and isotex are the materials with better thermal behaviour (lower decrement factor and greater time lag) like conventional materials, but with lower environmental impact. Regarding bricks, mixtures of 8% OCF and 7%WS generate more stable indoor temperatures than 4% OCF and 3%WS. Compared with conventional materials, building materials with incorporated biomass have better thermal behaviour and allow the construction of buildings with lower life cycle impact.
Graphical Abstract
Testing of drilling mud filter cake for low permeability micro-fracture plugging performance in shale rocks
Authors: Tian Yuexin , Liu Xiangjun , Luo Pingya , Liang Lixi , Xiong Jian , Huang Jinjun 
Published: June 2022

AbstractDespite the current demand for shale gas development, there is no means to evaluate nanoscale microfracture plugging technologies for ultra-low permeability formations. In this paper, we expand upon previous research and develop new means to create artificial fractures in model mud cake. By controlling the mud cake quality and strength, we developed mud cake with permeability that approached that of real mud shale. Low-permeability mud cake was prepared from barite powder, calcium carbonate, polyacrylamide, sodium polyacrylate, water, silica, a polycarboxylate comb macromolecule, a double sparse inhibitor, a film-forming agent and a mud cake curing agent. The mud cake permeability reached 5.9 × 10–4 mD and increased with soaking time to 1.3 × 10–3 mD (240 h). The equivalent opening of a single fracture did not change greatly and remained in the range from 3.93 × 10–5 m to 4.93 × 10–5 m. Plugging performance was evaluated by simulating microfractures and low-permeability environment of the formation. This method provides very important guidelines for the selection and development of nanoscale and microscale plugging agents and the evaluation of the plugging effect. It is also applicable to the evaluation of plugging performance in other fractured formations.
Current use and potential role of radioguided surgery in brain tumours
Authors: Collamati Francesco , Valdés Olmos Renato , Albanese Alessio , Cocciolillo Fabrizio , Di Giuda Daniela , Collarino Angela 
Published: June 2022

Abstract
Purpose
The aim of this mini-review is to discuss the possible role of radioguided surgery in brain tumours and, in particular, in gliomas.

Methods
A research in the PubMed/Medline database was carried out to identify relevant studies evaluating radioguided surgery in brain tumours.

Results
Radioguided surgery results using gamma (γ)-emitting tracers and γ-detection probes were summarised. Most importantly, the review included preliminary findings with novel approaches, particularly those relying on the use of beta (β)−emitting isotopes and a dedicated β probe.

Conclusion
Although few data are available in the current literature, the use of β probes could be useful to accurately identify surgical margins in brain tumours. Nevertheless, further in vivo studies are required.
Why Are They Buying It?: United States Consumers’ Intentions When Purchasing Meat, Eggs, and Dairy With Welfare-related Labels
Authors: Thibault Melissa , Pailler Sharon , Freund Daisy 
Published: June 2022

AbstractThere is widespread and growing concern among U.S. consumers about the treatment of farmed animals, and consumers are consequently paying attention to food product labels that indicate humane production practices. However, labels vary in their standards for animal welfare, and prior research suggests that consumers are confused by welfare-related labels: many shoppers cannot differentiate between labels that indicate changes in the way animals are raised and those that do not. We administered a survey to 1,000 American grocery shoppers to better understand the extent to which consumers purchase and pay more for food with certain labels based on an assumption of welfare improvement. Results showed that 86% of shoppers reported purchasing at least one product with the following labels in the last year: “cage or crate-free”, “free-range”, “pasture-raised”, “natural”, “organic”, “no hormone”, “no antibiotic”, “no rBST”, “humane”, “vegetarian-fed”, “grass-fed”, “farm-raised”. Of those who purchased one of the aforementioned labels, 89% did so because they thought the label indicated higher-welfare production practices, and 79% consciously paid more for the product with the label because they thought that the label indicated better-than-standard animal welfare. However, many of these labels lack uniform standards for the production practices they represent, and some labels represent production practices that do not influence animal welfare, thus the degree of the animal welfare impact of a given label is highly variable. These results indicate that labels need to clearly and accurately specify their animal welfare benefits to improve the consumers’ ability to purchase products that align with their expectations.
Photocatalytic Reforming of Biomass: What Role Will the Technology Play in Future Energy Systems
Authors: Skillen Nathan , Daly Helen , Lan Lan , Aljohani Meshal , Murnaghan Christopher W. J. , Fan Xiaolei , Hardacre Christopher , Sheldrake Gary N. , Robertson Peter K. J. 
Published: June 2022

AbstractPhotocatalytic reforming of biomass has emerged as an area of significant interest within the last decade. The number of papers published in the literature has been steadily increasing with keywords such as ‘hydrogen’ and ‘visible’ becoming prominent research topics. There are likely two primary drivers behind this, the first of which is that biomass represents a more sustainable photocatalytic feedstock for reforming to value-added products and energy. The second is the transition towards achieving net zero emission targets, which has increased focus on the development of technologies that could play a role in future energy systems. Therefore, this review provides a perspective on not only the current state of the research but also a future outlook on the potential roadmap for photocatalytic reforming of biomass. Producing energy via photocatalytic biomass reforming is very desirable due to the ambient operating conditions and potential to utilise renewable energy (e.g., solar) with a wide variety of biomass resources. As both interest and development within this field continues to grow, however, there are challenges being identified that are paramount to further advancement. In reviewing both the literature and trajectory of the field, research priorities can be identified and utilised to facilitate fundamental research alongside whole systems evaluation. Moreover, this would underpin the enhancement of photocatalytic technology with a view towards improving the technology readiness level and promoting engagement between academia and industry.
Spaces and Places for Connection in the Postdigital University
Authors: Gravett Karen , Baughan Patrick , Rao Namrata , Kinchin Ian 
Published: June 2022

AbstractThis study focuses on the spaces and places for learning and teaching connections in higher education. Using a photovoice research method, we ask: what role do spaces and places play in offering opportunities for learning and teaching connection, and what do they tell us about the evolving practices of teachers in contemporary higher education? Whilst considerable attention has been paid to the learning spaces of students, we argue that less attention has been devoted to the spaces in which educators learn. Our findings are considered against a backdrop of the ongoing disruption of the Covid-19 pandemic, meaning that opportunities for interaction have assumed even greater significance, and the ways in which we use and understand teaching spaces are in flux. As such, our data highlights how the move to digital and hybrid learning is blurring the boundaries of spaces and places, reorienting what it means to teach and to learn in a postdigital higher education landscape. We engage sociomaterial and spatial concepts to examine how spaces entangle with university teachers’ experiences, and we explore the shifting nature of interaction and space in post-pandemic times.
Multi-objective optimization of aircraft landing within predetermined time window
Authors: Xia Qingjun , Ye Zhijian , Zhang Zhaoyue , Lu Tingting 
Published: June 2022

AbstractThis study presents a multi-objective optimization model to solve aircraft landing problem within a predetermined time window. Minimizing total fuel cost, minimizing total delays, maximizing throughput, and maximizing fairness are considered to construct the multi-objective optimization model. According to the different weights of objectives, the first-come-first-serve and simulated annealing are used to solve the multi-objective optimization problem. The algorithms’ feasibility is analysed and a suggestion about how to get satisfactory solutions for all stakeholders is given through the expert evaluation method. The results show that the simulated annealing can get better solution than the first-come-first-serve when the number of flights exceeds 10.