bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Immunotherapy in Pythium insidiosum Keratitis
Authors: Thanathanee Onsiri , Bhoomibunchoo Chavakij , Anutarapongpan Orapin , Suwan-apichon Olan , Charoensuk Korawin , Chindamporn Ariya 
Published: June 2022

ABSTRACT.
Pythium keratitis is a potentially devastating ocular condition. Incidence of Pythium keratitis has been reported in tropical and subtropical areas. In previous reports, there were no effective or standard treatments, and combinations of medication, immunotherapy, and surgery were proposed. Pythium insidiosum antigen immunotherapy (PIAI) showed an acceptable safety profile, but its efficacy is questionable in Pythium keratitis. This retrospective review included 10 eyes from 10 patients. All cases were confirmed diagnosis of P. insidiosum keratitis by culture and/or polymerase chain reaction. Three doses of PIAI were injected at 2-week intervals in all patients. The infiltration diameter ranged from 5.2 mm to total corneal involvement, and eight cases (80%) had hypopyon. Therapeutic penetrating keratoplasty (TPK) or scleral graft were undertaken in nine cases. Enucleation was done in one case on the first visit. A second TPK was undertaken in three cases, and two globes were saved. Two cases in the globe salvage group received voriconazole via eyedrops and intracameral injection. No case received either linezolid or azithromycin. Three of nine eye globes (33.33%) were saved. PIAI did not show efficacy in the treatment of Pythium keratitis. Radical surgery including resurgery in recurrence is an approved effective treatment. The recently reported medications may offer supportive management.
Assessment of the sensorimotor integration development in primary school children from Wroclaw, Poland: a prospective observational study
Authors: Górna Sara , Domaszewska Katarzyna , Choińska Anna Maria 
Published: June 2022

IntroductionSenses are essential in the development of psychomotor functioning in healthy 7-year-old children who enter school. The aim of the study was to assess the level of sensorimotor integration in children starting school education.MethodsThe study involved 82 children from primary schools. The first examination (T1) was carried out at the beginning of the 2018/2019 school year; the second examination (T2) was performed after a 6-month interval. The level of sensorimotor integration development was measured by the Southern California Sensory Integration Test (SCSIT) in 11 sensory categories.ResultsIn 10 out of the 11 SCSIT tests, the children obtained statistically significantly higher mean results after 6 months of education (T2) than at the beginning of the school year (T1) (<i>p</i> < 0.05). The scores achieved at T1 in SCSIT showed that the following risks of sensorimotor integration disorders were found most often: deep sensation disorders (kinaesthesia test) among 13.4% of the children and incorrect processing of superficial feeling (graphesthesia test) among 12.2%.ConclusionsThe beginning of early childhood education is a difficult period for children to adapt to school requirements. With 7-year-old children starting school education, attention should be paid to their potential difficulties related to abnormalities in deep sensation, especially kinaesthesia (orientation in the positioning of the body parts) and graphesthesia (ability to ‘read’ shapes).
Gender Perception on Flexi and Virtual Time and Work Life Balance
Authors: Jyoti  , Jaya  , Arora Madhu 
Published: June 2022

The research is aimed to study perception of males and females regarding Flexi time and work-lifebalance. The research is descriptive in nature and data is collected from 380 working professionals using questionnaire on google forms (including males and females). T test is used to know the empirical results. It is found that Although flexi work arrangements are important for reducing attrition rate but along with that a strong policy is also required to cope up with the challenges faced in the workplace.
Analisis Strategi Pengembangan Bisnis Rumah Makan Wong Solo Di Kendari
Authors: Rahmawati Fitrah , Bake Jamal , Purwati Ninik Endang 
Published: June 2022

This Research aim to to know the strategy of development of Restaurant business Wong Solo in Kendari. Informan in this research that is perpetrator of is effort restaurant of Wong Solo consisted of by the head of is effort and other employees as much 5 people. Technique of data collecting used by is interview mendalam, dokumentasi. Research method used by is descriptive approach analyse with the approach qualitative with the research process of through/ passing permanent measurement by means of that is matrix SWOTResult of this research indicate that the: strategy of development of business of restaurant of Wong Solo that is strategic location determination by exploiting reliable human resource management is its area is elementary substance election goodness and also product processing becoming especial menu with the goal feel typical and also the make-up of service, taking care of security and kenyamantehadapcutomer/ client. S0 that born the prima service strategy with the method Greeting. Greeting is expression or greet with the method: 1) greeting guest with the greeting of according to company standard, 2) smile the heartfelt, 3) bring the guest clothes that have been provided according to the number of guests.ABSTRAK Penelitian ini bertujuan untuk mengetahui strategi pengembangan bisnis Rumah Makan Wong Solo di Kendari. Informan dalam penelitian ini yaitu pelaku usaha rumah makan Wong Solo yang terdiri dari pimpinan usaha dan karyawan lainnya sebanyak 5 orang. Teknik pengumpulan data yang digunakan adalah wawancara mendalam, dokumentasi. Metode penelitian yang digunakan adalah pendekatan deskriptif analisis dengan pendekatan kualitatif dengan proses penelitian melalui pengukuran dengan alat yang baku yaitu matriks SWOT.Hasil penelitian ini menunjukkan bahwa :strategi pengembangan bisnis rumah makan Wong Solo yaitu penentuan lokasi yang strategis dengan memanfaatkan manajemen sumberdaya manusia yang handal dibidangnya baik pemilihan bahan dasar maupun pengolahan produk yang menjadi menu utama dengan cita rasa yang khas serta peningkatan layanan, menjaga keamanan dan kenyaman terhadap pelanggan. Sehingga lahirlah strategi pelayanan prima dengan metode Greeting. Greeting adalah ungkapan sambutan atau salam dengan metode: 1) menyambut tamu dengan sambutan sesuai standar perusahaan, 2) senyum dengan tulus, 3) mengantar tamu kemeja yang sudah disediakan sesuai dengan jumlah tamunya.
Association of sonographic grading of fatty liver disease with liver function tests and CT hounsfield
Authors: Bhardava Vishalkumar , Agrawal Vatsal , Patel Loma , Suri Mohik 
Published: June 2022

Fatty Liver Disease (FLD) is described as the accumulation of triglycerides within cytoplasmic vesicles of hepatocytes exceeding 5 percent of total liver weight. It is generally of two types: Alcoholic or Non-alcoholic FLD (NAFLD). It has a tendency to progress and cause steatohepatitis, brosis, cryptogenic cirrhosis, hepatocellular carcinoma, chronic liver disease, metabolic syndrome, polycystic ovarian syndrome and adenocarcinomas. Objective: To nd association of Sonographic Grading of Fatty Liver Disease with Liver Function Tests and CT Hounseld units. The evaluation of the signicance of Ultrasound and LFTs over Computed Tomography is the aim of this study for the diagnosis of Fatty Liver Disease. Method: patients were undergone CT exams, Ultrasound exams and LFT tests for this this study (mean age: Their hepatic Hounseld units were obtained, Ultrasonographic grades were specied and LFTs were recorded. Results: The sonographic grading of fatty liver is significant/ not, taking HU value as standard. Conclusion: It is concluded that Ultrasound is effective in diagnosing this disease in all grades of FattyLiver Disease along with Liver Function Tests.
Caracterización de las plantas melíferas en la producción y conservación de las abejas
Authors: Pinell-Tórrez J. M. , Martinez-Centeno A. L. , Huerta-sobavarro K. K , Salinas-Hernández B. G. 
Published: June 2022

El objetivo del presente estudio se centró en caracterizar las plantas melíferas que contribuyen en la producción y conservación de las abejas. La investigación se desarrolló con base en la delimitación del área de muestreo, la revisión de información reportada en la literatura especializada, la identificación taxonómica de especies vegetales, Se trabajó con 12 productores apícolas de los municipios de Jinotega, San Rafael, Yalí, El Cuá. Como resultado del estudio se identificaron 50 plantas pertenecientes a 10 tipos de familias diferentes, destacándose así la familia de las Fabaceae, también se determinó que existe una mayor floración entre los meses de marzo - mayo, y de septiembre - octubre la floración disminuye en todas las zonas. Es importante diversificarlas con especies que sean multiflorales, debido a que se han ido perdiendo con el paso del tiempo a través de diferentes acciones antropogénicas como el despale, cambio de uso de suelos, cambio climático y uso indiscriminado de insumos químicos. Por otro lado, se identificó que las abejas prefieren las zonas de diversas plantas pertenecientes a las áreas de cultivos en asocios, debido a que sus flores tienen un color y olor llamativos para las abejas, además que poseen una mayor cantidad de polen y néctar, por ende se tiene un aumento de polinización, contribuyendo así a la conservación de las diferentes especies en la zona y mejorando rendimientos de fructificación de los diferentes cultivos presentes en el área productiva.
FIBROMIALGIA ASSOCIADA AOS TRANSTORNOS MENTAIS: DEPRESSÃO E ANSIEDADE
Authors: PITA Lucas , ARAÚJO Lorhany Jaynne Filgueiras , FECHINE Janne Caroline Oliveira Gomes , DAMASCENO Lilian Coelho , DE ARAÚJO Jordana Figueiredo 
Published: June 2022

Fibromialgia é uma síndrome neurológica crônica e condição reumática sem inflamação. A etiopatogenia é desconhecida e está relacionada a doenças autoimunes, a fadiga generalizada, rigidez matinal, estresse, distúrbios do sono, ansiedade e depressão, interferindo na qualidade de vida em geral do paciente. O artigo em questão tem o objetivo de compreender a relação da FM com algumas patologias psicológicas, como a depressão e ansiedade. Além disso, tem caráter descritivo e exploratório. Trata-se de uma revisão de literatura bibliográfica em que a busca foi por meio da base de dados eletrônicos MEDLINE, LILACS e SciELO, em que utilizou-se como tema central fibromialgia associadas aos transtornos mentais. Aos resultados, a pessoa diagnosticada com FM, está propensa a desenvolver ansiedade, tensão, depressão, insônia, e alterações no ciclo de dor. Os transtornos mentais mencionados são consequências da FM, visto que ao reduzir serotonina (via descendente), hormônio responsável pela regulação do humor, sono, apetite, ansiedade e emoções o paciente fica com extrema labilidade emocional, concluindo com tratamento da patologia associar terapia medicamentosa com terapia não medicamentosa.
Corpo que fala: O mito da beleza feminina e sua relação com a sexualidade da personagem Alice, de Lygia Fagundes Telles
Authors: Oliveira Jéssica França de , Corrêa Adriana De Oliveira Alves 
Published: June 2022

Este artigo apresenta uma análise do conto Emanuel, presente no livro Um coração ardente (1981; 2012), de Lygia Fagundes Telles, tendo como objetivo observar as relações discursivas e conflitos que envolvem a corporeidade e a sexualidade da mulher, representada pela personagem Alice. O quadro teórico é constituído por autores como: Michel Foucault (1988), Naomi Wolf (1992), Judith Butler (2003), Silvia Federici (2004), Andreá Osório (2011) e Losandro Tedeschi (2012). Compreende-se que a protagonista reproduz em seu discurso um sistema sobre dominação masculina, buscando um gozo impedido pela sua virgindade madura. Ao contrapasso, esse gozo se faz na dualidade das palavras.
As relações homossexuais em Mulher Mat(r)iz, de Miriam Alves
Authors: Drey Letícia Gabriele , Paz Demétrio Alves 
Published: June 2022

O artigo analisa três contos da obra Mulher Mat(r)iz (2011), de Miriam Alves: “Abajur”, “Os olhos verdes de Esmeralda” e “Minha flor, minha paixão”. Nas três narrativas há personagens homossexuais que sofrem algum tipo de discriminação ou violência. O nosso suporte teórico são obras de Moema Parente Augel, Judith Butler, Angela Davis, Audre Lorde, que nos ajudaram a perceber as relações entre sexualidades e identidades nos contos. A representação que a autora propõe é importante para se pensar a constituição do “ser mulher” e do “ser homem” na sociedade contemporânea. As mulheres na obra de Miriam Alves assumem importantes papéis representativos na luta contra o racismo, a homofobia, a violência de gênero e os padrões androcêntricos. Desse modo, a literatura afro-brasileira de autoria feminina, além de propiciar a representação e autorrepresentação da mulher negra como escritora e protagonista, apresenta distintas formas de ser e estar no mundo.
Apresentação do dossiê temático Feminismos e Sexualidades Plurais em Tempos Singulares
Authors: Martins de Souza Martha Júlia , Silva Bezerra Fábio Alexandre , Bolfarine Mariana , Lucena Dalmaso Renata 
Published: June 2022

Apresentação do Dossiê Temático: Feminismos e Sexualidades plurais em tempos singulares
ANALISIS NILAI CT-NUMBER PADA CT-SCAN THORAX DENGAN KASUS COVID-19
Authors: Putra Gede Dharma , Juliantara I Putu Eka , Prasetya I Made Lana 
Published: June 2022

Background : Computed Tomography (CT) scanner is an imaging tool used to obtain images of certain parts of the body using X-rays. CT-Scanner more detailed image, compared to X-ray, CT Number is the value of the X-ray attenuation coefficient (energy attenuation) determined by the average X-ray calculated in Hounsfield Units (HU) which is a standard facility that always is on the CT-Scan plane. Thorax CT-Scan is a radiological examination technique to obtain anatomical information of cross-sectional slices such as axial, coronal and sagittal. Coronavirus Disease 2019 (Covid-19 ) is an infectious disease caused by a species of coronavirus, namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). As a recent study, the CT-Scan abnormality that is most often observed in Covid-19 patients is ground glass opacity (GGO).
Methods : This research uses descriptive quantitative with an observational approach. This measurement uses the Region Of Interest (ROI) to determine the value of the CT Number, where the Region Of Interest (ROI) is directed at the picture that contains a pathological abnormality of Grond Glass Opacity (GGO) on the CT-Scan Thorax in cases of Covid-19 then the CT Number value is compared with results of research conducted by Ali & Ghonymy, (2020).
Result and Coclusion : Shows that there is a range of CT Number values ​​using quartile 3 or 75% percintile with the result of : -167 HU, Maximum : -74 minimum value : -288 HU. This means that it is a pathological Grond Glass Opacity (GGO) for Covid-19 patients.
PENERAPAN TERAPI EXPRESSIVE WRITING UNTUK MENURUNKAN STRESS PADA MAHASISWA YANG SEDANG MENYELESAIKAN KARYA TULIS ILMIAH
Authors: Khosim Azhari Nanang , Anggarawati Tuti , Wahyu Elisa 
Published: June 2022

Latar belakang: Mahasiswa tingkat akhir memiliki tanggungjawab menyelesaikan tugas akhir yaitu menyelesaikan karya tulis ilmiah sebagai syarat kelulusan dan memperoleh gelar. Dalam proses menyelesaikan karya tulis ilmiah terdapat berbagai kendala yang menyebabkan stress pada mahasiswa. Salah satu upaya yang dapat dilmelakukan terapi expressive writing. Tujuan : menggambarkan penurunan skor stress pada mahasiswa tingkat akhir sebelum dan sesudah dilakukan terapi expressive writing. Metode: Rancangan penelitian yang digunakan adalah deskriptif dengan metode pendekatan studi kasus. Subyek dalam penelitian menggunakan dua orang mahasiswa tingkat akhir yang mengalami stress ringan sampai stress sangat berat. Penilaian skor stress diukur dengan menggunakan alat ukur Depression Anxiety Stress Scale (DASS). Hasil: Hasil studi kasus didapatlan bahwa skor stress pada subyek I dengan skor 41 dengan kategori stress sangat verat turun menjadi skor 20 dengan kategori stress sedang, dan untuk subyek II dengan skor 39 dengan kategori stress sangat berat turun menjadi 20 akukan dilakukan untuk mengurangi stress adalah dengan dengan kategori stress sedang. Saran : terapi expressive writing dapat digunakan dalam menurunkan skor stress pada mahasiswa tingkat akhir yang sedang menyelesaikan karya tulis ilmiah
IMPACTO DO TRAUMATISMO DENTÁRIO NA QUALIDADE DE VIDA DE CRIANÇAS E ADOLESCENTES: REVISÃO DE LITERATURA
Authors: Luanne Gonçalves Pimentel Kaddja , Souza da Silva Janayna , De Matos Vilas Boas Aline , Affonseca Pedreira Amanda , Dourado Martins Cerqueira Joana , Porto Edla Carvalho 
Published: June 2022

Introdução: O Trauma dental é um distúrbio oral comum em crianças, causado por um impacto externo sobre o dente e/ou tecidos circundantes. Objetivo: Revisar o impacto do trauma dental na qualidade de vida de crianças e adolescente. Métodos: Foi realizada uma busca bibliográfica na Biblioteca Virtual de Saúde (MEDLINE, LILACS, BBO). Artigos duplicados, revisão de literatura e teses foram excluídos e como critério de inclusão foram utilizados artigos publicados de 2010 até 2020. Logo após, foi realizada a extração dos dados para análise dos estudos com mais precisão, organizando as informações em uma tabela padronizada. Resultados: Dos 429 artigos encontrados, apenas 9 estudos apresentaram todas as informações exigidas nos critérios metodológicos, abrangendo a faixa etária de 2 a 15 anos. Para avaliação do impacto do trauma dental na qualidade de vida relacionada a saúde bucal 6 dos estudos utilizaram a versão Brasileira do questionário (CPQ), 2 utilizaram a versão Brasileira do questionário sobre qualidade de vida (B-ECOHIS) e apenas 1 utilizou a versão Brasileira do (BP-CPQ). Foi observado que dos nove trabalhos apenas um não observou associação estatisticamente significativa entre a qualidade de vida e o trauma dental. Conclusão: O trauma dental possui influência negativa na qualidade de vida das crianças e adolescentes associados às limitações funcionais, bem-estar social e emocional.
Conducting Hormonal, Biochemical and Serological Tests in Autoimmune Thyroid Patients
Authors: Albadrani Afraa Abdul-Sattar , Altobje Mahmood Abduljabbar 
Published: June 2022

Background: One of the most frequent autoimmune illnesses affecting the thyroid gland is immunological thyroid disease. Antibodies against the enzyme thyroglobulin and thyroid-stimulating hormone receptors are produced by the immune system. Hashimoto's disease and Graves' disease are the two primary forms of autoimmune diseases.
Methods: 91 blood samples were taken, including 71 for thyroid disease patients and 20 for healthy persons as control samples, from both sexes and of various ages. The tests were performed using a variety of methodologies.
Results: Some of autoantibodies were found in varying quantities in 44 individuals. While TPO antibodies were found in 75% of 33 individuals, Anti-TG Ab was found in 72.72% of the patients, 15.90% in seven patients, and anti-TSHR Ab and antinuclear antibodies were found in 22.72% of the patients compared to the control samples. Any type of autoantibody, as well as the results of hormonal testing, revealed disease in a variety of individuals at varying rates. Because the patients were on therapy, the highest rate was 59.09% for thyroid-stimulating hormones. Chemical analyses revealed a sugar and fat imbalance with no discernible link. Interleukin 4 was detected in 4 individuals (9.09%), including one patient with autoimmune hypothyroidism (2.27%) and three patients in C3 18 with immunological hyperthyroidism (6.82%). The findings revealed an increase in complement molecule concentration in 40.90% of patients, including 15 patients with autoimmune hypothyroidism (34.09%) and 3 patients with immune thyroid gland C3 hyperactivity (6.71%). The statistical study revealed a P < 0.01 level of significance correlation between the presence of sugar and triglycerides and the complement molecule. Interleukin 4 and antibodies to receptors have a substantial correlation at the P < 0.01TSHR Ab level TSH.
Conclusions: The C3 gland patients for thyroid peroxidase had the largest amount of antibodies, lipids, and sugar, according to the study. Interleukin-4 occurred in certain individuals who had antibodies to thyroid-stimulating hormone receptors, according to the research.
Rheumatologist and Patient Mental Models for Treatment of Rheumatoid Arthritis Help Explain Low Treat‐to‐Target Rates
Authors: Hsiao Betty , Downs Julie , Lanyon Mandy , Blalock Susan J. , Curtis Jeffrey R. , Harrold Leslie R. , Nowell William Benjamin , Wiedmeyer Carole , Venkatachalam Shilpa , Fraenkel Liana 
Published: June 2022

ObjectiveDespite proven benefits, less than half of patients with rheumatoid arthritis (RA) are treated using a treat‐to‐target (TTT) strategy. Our objective was to identify critical discrepancies between rheumatologist and patient mental models related to the treatment of RA to inform interventions designed to increase implementation of TTT.MethodsWe developed rheumatologist and patient mental models using the Mental Models Approach to Risk Communication. We conducted semistructured interviews to elicit views related to RA treatment decisions with 14 rheumatologists and 30 patients with RA. We also included responses (n = 284) to an open‐ended question on a survey fielded to augment qualitative descriptions from the interviews. Interviews were transcribed and coded independently by two members of the research team.ResultsRheumatologist and patient mental models for RA treatment are significantly more complex than the TTT model. Both consider domains (system factors and patient readiness) outside of disease activity measurement, target setting, and risk versus benefit assessment in their decision‐making. Furthermore, specific factors were found to be unique to each model. For example, the physician model stresses the importance of evaluating disease activity over time and patient adherence. In contrast, patients discussed the impact of chronic disease weariness, medication‐related fatigue, the importance of feeling adequately informed, and stress associated with changing medications.ConclusionWe found several discrepancies primarily related to information gaps and differences in how patients and physicians value trade‐offs that can serve as specific targets to improve patient–physician communication and ultimately inform interventions to improve uptake of TTT.
Real‐Time Mass Change: An Intrinsic Indicator to Dynamically Probe the Electrochemical Degradation Evolution in WO3
Authors: Wang Zhenhua , Zhang Xin , Zhang Hongliang , Ge Fangfang , Wang Qiang , Zhang Chengli , Xu Guanglong , Gao Junhua , Rogachev A. A. , Cao Hongtao 
Published: June 2022

AbstractAlthough tungsten trioxide (WO3) films are considered as the most popular inorganic electrochromic cathode, the irreversible accumulation of lithium ion in it leads to the degradation of cycling stability. In situ monitoring of mass change is critical to intrinsically probe the dynamical degradation evolution of the WO3 films. Based on electrochemical quartz crystal microbalance analysis, a transfer model based on the migration of three mass carriers (lithium ion, perchlorate ion and propylene carbonate) is proposed. Higher potential can boost the migration of mass carriers, benefiting from the intensive driving force. Due to moderate intercalation of mass carriers and smallest difference in molar mass, the excellent electrochemical reversibility at 40 mV s−1 is observed. As the migration of mass carriers progresses, continuous corrosion of the WO3 films results in electrochemical degradation. It is demonstrated that electrochemical quartz crystal microbalance‐based analyses provide a valuable insight for the intercalation and extraction of mass carriers, in favor of further revealing degradation evolution induced by the irreversible intercalation of conductive ions in electrochemical devices.