bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Sybil Attack Detection Scheme in MobileIoT Based on Collaborate Edge Computing
Authors: Yan Junwei , Jiang Tao , Lin Liwei , Wu Zhengyu , Ye Xiucai 
Published: September 2022

Abstract
Background: The Internet of things (IoT) connects all items to the Internet through information-sensing devices to exchange information for intelligent identification and management. Sybil attack is a famous and crippling attack in IoT. Most of the previous methods of detecting Sybil attacks in IoT mainly focus on static IoT while there are very rare methods applicable to mobile IoT. Results: In this paper, a novel, lightweight, and distributive detection scheme based on edge computing is proposed for detecting Sybil attacks in mobile IoT. In the proposed scheme, detection consists of two rounds. In each round, member nodes are required to send packets to edge nodes. Edge nodes calculate a possible interval of the received signal strength indication (RSSI) from the first round and check whether the RSSI from the second round is in the interval to detect Sybil attacks. Extensive experimental studies are included to show that the presented approach outperforms many existing approaches in terms of true detection and false detection rates.
Enhanced Structural, Dielectric, and Magnetic Properties of Mn-Yb-doped Y-type Hexaferrites
Authors: Nadeem Muhammad , Khan Hasan Mehmood , Buzdar saeed ahmad , Ahmad Javed , Asari Muammad A , mran Muhammad , Aleem Ambreen , nisa mehrun , Raza Muhammad Ehsan 
Published: September 2022

Abstract
This study aimed to determine the effect of Mn2+ and Yb3+ ions substitution on the structural, dielectric, morphological, and magnetic properties of CaBaCo2 − xMnxYbyFe12−yO22 where x = 0.00-0.1 and y = 0.00-0.01 Y-type hexagonal ferrites prepared by sol-gel auto combustion. For 6 hours, samples were calcined at 1050 degrees Celsius. X-ray diffraction (XRD) analysis was used to study the formation phase of Y-type hexaferrites. The calculated structural auxiliary parameters, such as lattice constants (a and c), cell volume (Vcell), X-ray density (dx), bulk density (db), and porosity (P), were found to be within the following ranges: a = 5.891 to 5.9Å, c = .43.466 to 43.543Å, Vcell 1310.53 to 1312.26Å3, dx = 5.01 to 5.05(g/cm− 1) db = 2.622 to 3.032 (g/cm− 1)and P = 39.969 to 47.665%. The location of the ions, including their respective bonds, inside the structure of the lattice matrix, was revealed by Fourier-transform infrared spectroscopy (FTIR). SEM pictures confirmed the plate-like shape of the particles, confirming the XRD findings. In the dielectric analysis, the typical dielectric response of ferrites was observed. Grain contribution is low when compared to grain boundaries contribution The generated Y-type hexaferrites samples' multidomain magnetic nature resulted in domain wall displacement, which affects the coercivity values. A vibrating sample magnetometer was used to investigate magnetic characteristics (VSM). The saturation magnetization (Ms), Retentivity (Mr), and coercivity (Hc) of the material were found to be 4.11 to 2.21 emu/g, 2.33 to 1.22emu/g, and 1776.78 to 2283,51Oe, respectively. These powders can be used as pre-eminent contender materials for perpendicular recording media (PMR) applications. Corresponding Author’s E-mail: hmkhan@iub.edu.pk
Leu-Life: A Smart Application for Leukemia Cancer Patients Based on Machine Learning
Authors: Elhishi Sara , Alzeky Salma , El-Metwally Aya , Burham Basmala , Ragab Somaya , Elgayar Samah , Mansour Samar , El-Sayed Nada , El-Azab Zeinab , Mohamed Zeinab , El-Dein Mai 
Published: September 2022

Abstract
Leukemia cancer poses a risk to life as acute or chronic leukemia can manifest themselves more severe symptoms. The most frequent type of leukemia cancer is acute lymphoblastic leukemia (ALL). ALL affects about 20% of adult leukemias and presents in 80% of childhood leukemias. ALL diagnosing is very complex that requires labor-intensive, sophisticated procedures. One of the most important criteria of a healthcare system is to give the patient the best possible care based on an examination of their medical history, lifestyle choices, and any molecular trait variability. Several intelligent technologies that are based on machine learning and data-driven methods have been developed to address these problems. this paper examines statistical and machine learning methods. We also provide a trustworthy cloud-based data storage paradigm and a safe Android-based architecture for gathering patient data. The paper introduces the Leu-Life, a m-health android application that uses machine learning methods to detect leukemia cancer along with providing a set of features that helps in managing and facilitating life of leukemia cancer patients. The discussion will conclude with a predictive algorithm that may categorize leukemia cancer based an input of a blood file.
Genetic determinants of macrolide and tetracycline resistance in penicillin non-susceptible Streptococcus pneumoniae isolates, from Tanzania
Authors: Manyahi Joel , Moyo Sabrina J , Langeland Nina , Blomberg Bjørn 
Published: September 2022

Abstract
Background: Over million yearly deaths are attributable to Streptococcus pneumoniae and the emergence of penicillin non-susceptible Streptococcus pneumoniae (PNSP) challenges therapy of pneumococcal disease. The aim of this study was to determine the mechanisms of antibiotic resistance among PNSP isolates by next generation sequencing.
Methods: We assessed 26 PNSP isolates obtained from the nasopharynx from 537 healthy human immunodeficiency virus (HIV) infected adults in Dar es Salaam, Tanzania, participating in the randomized clinical trial CoTrimResist (ClinicalTrials.gov identifier: NCT03087890, registered on 23rd March, 2017). Next generation whole genome sequencing on the Illumina platform was used to identify mechanisms of resistance to antibiotics among PNSP.
Results: Fifty percent (13/26) of PNSP were resistant to erythromycin, of these 54% (7/13) and 46% (6/13) had MLSBphenotype and M phenotype respectively. All erythromycin resistant PNSP carried macrolide resistance genes; six isolates had mef(A)-msr(D), five isolates had both erm(B) and mef(A)-msr(D) while two isolates carried erm(B) alone. Isolates harboring the erm(B) gene had increased MIC (>256µg/mL) towards macrolides, compared to isolates without erm(B) gene (MIC 4-12µg/mL) p<0.001. Using the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines, the prevalence of azithromycin resistance was overestimated compared to genetic correlates. Tetracycline resistance was detected in 13/26 (50%) of PNSP and all the 13 isolates harbored the tet(M) gene. All isolates carrying the tet(M) gene and 11/13 isolates with macrolide resistance genes were associated with the mobile genetic element Tn6009 transposon family. Of 26 PNSP isolates, serogroup 19 (serotype 19A, 19F) was the most common (9/26), and sequence type ST271 accounted for 15% (4/26). Serogroup 19 displayed high-level macrolide resistance and carried both macrolide and tetracycline resistance genes.
Conclusion: The erm(B) and mef(A)-msr(D) were common genes conferring resistance to MLSB in PNSP. Resistance to tetracycline was conferred by the tet(M) gene. Resistance genes were associated with the Tn6009transposon.
Efficacy of risk-stratified screening for gastric cancer: a retrospective repeated cross-sectional study in Yokosuka, Japan
Authors: Matsuoka Mikio , Taguri Masataka , Mizuno Yasuhiro , Kimura Masayuki , Endo Chihiro , Tsuburaya Akira 
Published: September 2022

Abstract
Background
Gastric cancer (GC) is mostly related to Helicobacter pylori (Hp) infection, and risk-stratified screening (RS) for GC has been adopted in some cities. We aimed to investigate the efficacy of RS as compared with barium X-ray screening (XR) recommended by Japan for GC.
Methods
Repeated cross-sectional study from the data of Yokosuka Public Health Center. The GC screening participants were ≥ 40 years old from 2002 to 2018. RS was classified by pepsinogen test screening (PG) and Helicobacter pylori (Hp) tests into low and high-risk groups. The primary endpoints were detection rates of all GC and early GC (TNM T1). Secondary endpoints were participation rate and GC detection cost. For GC detection, the odds ratios were calculated by logistic regression models adjusted for age, sex, and first visit or revisit.
Results
A total of 448,244 participants’ data were included. In multivariable analyses, the odds ratios of PG and RS vs XR were 2.26 and 3.73 for GC detection, and 4.64 and 10.63 for early GC detection, respectively (p < .00001). The citizens’ participation rate increased significantly from 3.9% in XR to 22.2% in RS, and 23.1% in RS. Hp eradication was successful in 83.9% of the high-risk groups. GC detection cost by RS was 29.99 and 1.60 times lower as compared with XR and PG, respectively (p < 0.0001).
Conclusions
RS was more effective than XR for detecting GC and the detection cost was lower. RS might contribute to citizens’ future survival by the improved early GC detection, participation, and Hp eradication system.
Risk factors for early occurrence of malnutrition in infants with severe congenital heart disease
Authors: Mignot Margot , Huguet Helena , Cambonie Gilles , Guillaumont Sophie , Vincenti Marie , Blanc Julie , Ovaert Caroline , Picot Marie-Christine , Karsenty Clement , Amedro Pascal , Kollen Laura , Gavotto Arthur 
Published: September 2022

Abstract
Purpose: To identify the risk factors of early occurrence of malnutrition in infants with severe congenital heart disease (CHD) during their first year of life.
Methods and Results: Retrospective longitudinal multicentre study carried out from January 2014 to December 2020 in two tertiary care CHD centres. Four CHD hemodynamic groups were identified. Malnutrition was defined by a Waterlow score under 80% and/or the need for calorie-enriched formula. A total of 216 infants with a severe CHD, e.g., requiring cardiac surgery, cardiac catheterization, or hospitalization for heart failure during their first year of life were included in the study. Malnutrition was observed among 43% of the cohort, with the highest prevalence in infants with increased pulmonary blood flow (71%) compared to the others hemodynamic groups (p<0.001). In multivariate analysis, low birthweight (OR 0.62, 95% CI 0.44-0.89, p=0.009), CHD with increased pulmonary blood flow (OR 4.80, 95% CI 1.42-16.20, p=0.08), heart failure (OR 9.26, 95% CI 4.04-21.25, p<0.001), and the number of hospitalizations (OR 1.35, 95% CI 1.08l-1.69, p=0.009) during the first year of life were associated with malnutrition (AUC 0.85, 95% CI 0.79-0.90).
Conclusion: In infants with a severe CHD, early occurrence of malnutrition during the first year of life affected a high proportion of subjects. CHD with increased pulmonary blood flow, low birthweight, heart failure, and repeated hospitalizations were risk factors for malnutrition. Further studies are required to identify optimal nutritional support in this population.
The effect of magnesium on vitamin D, bone mineral density, chronic diseases and knee osteoarthritis
Authors: YILMAZ Ebru , ÜNVER Sena 
Published: September 2022

Abstract
Objective: Magnesium (Mg) is mandatory for sustaining numerous physiological cellular functions. The study’s goal was to define whether the Mg level could affect the level of vitamin D, bone mineral densitometry (BMD), chronic diseases and radiological stage in patients with knee osteoarthritis (OA).
Methods: 98 patients (62 female, 36 male) with a diagnosis of at least grade 1 knee OA were included in the study. Data including age, sex, body mass index (BMI), smoking, menopausal status, duration of menopause, family history of osteoporosis, the presence of chronic diseases (hypertension=HT, diabetes mellitus=DM, hyperlipidemia=HPL, coronary artery disease=CAD, hypothyroidism=HPT) and radiological stage of knee OA were collected. The serum Ca, Mg, alkaline phosphatase (ALP), PTH and 25(OH)-vitamin D levels were recorded. In addition, whole patients performed anteroposterior radiography of the knee by using X-Ray, and BMD of the femoral neck and lumbar vertebrae (L1-L4) by using dual-energy X-Ray absorptiometry (DEXA). The presence of osteoporosis was accepted as T scores ≤ -2.5.
Results: The mean age was 59.15±10.58 years in the study. A statistically significant relationship was found between the level of Mg and age, smoking, presence of chronic disease, duration of menopause, vitamin D level, PTH level, and femoral neck T score (p< 0.05).
Conclusion: Mg appears to be a useful effect on the organizing of vitamin D and PTH metabolism, osteoporosis and various chronic diseases. Future trials are needed to explore the link between Mg and knee OA.
Influence of Water Saturation on Curtain Formation of Frozen wall
Authors: Li Hewan , Liu Jian , Wang Laigui , Ren Tianjiao 
Published: September 2022

Abstract
In the process of in-situ mining of underground oil shale, underground Frozen wall are often used for water seal and wall retaining, And the water saturation of the frozen soil affects the formation of the freezing circle. Using the methods of theoretical analysis, Indoor similar simulation test and numerical simulation to be obtained the temperature drop process and freezing time around the Frozen wall under different water saturation conditions, and use finite element software for simulation verification. The experimental and simulation results show that:1) With the increase of water saturation, the longer the freezing time at the center of the connection line of the Frozen wall, the more difficult is to form the Frozen wall closure, and the worse the freezing effect is; 2) The temperature change trend of the center point is different under different water saturation, the higher the water saturation, the slower the initial temperature decline rate, when the water saturation is 100%, the initial temperature drop hysteresis phenomenon occurs, and the Frozen wall closure begins to form gradually until 192.4 min in the experiment; With the increase of water saturation, the influence range of the two Frozen walls in the model gradually decreases at the same time. Therefore, the groundwater content (quantitative result) has a great influence on the formation time of the Frozen wall, the research results can provide reference for the design of underground Frozen wall in high-temperature mining of oil shale.
WITHDRAWN: Aperiodically intermittent H∞ synchronization control of Markov jumping reaction-diffusion neural networks with time-varying delays *
Authors: Wang Xuelian , Du Xin 
Published: September 2022

Abstract
This paper is concerned with the exponential synchronization of reaction-diffusion neural networks subject to Markov jumping parameters and time-varying delays, in which the aperiodically intermittent control is adopted to save network bandwidth resources to a certain extent. Different from some previous literature, the diffusion effects are considered in this paper, and thus the system model is expressed by partial differential equations, where the states depend not only on time but also on space. Then, based on the Lyapunov-krasovskii functional technique, some sufficient criteria are obtained to ensure that synchronization error systems are the exponential stability and satisfy a predetermined H∞ performance index. Finally, two examples are provided to verify the validity of obtained results.
Refractive Status and Amblyopia Risk Factors in Premature Infants with Different Gestational Age and Birth Weight
Authors: Cao Yiwen , Yang Liu 
Published: September 2022

Abstract
Objective: To explore amblyopia risk factors in premature infants vs. full term infants, low birth weight(LBW) vs. very low birth weight(VLBW) infants, and moderately/late preterm(PT) vs. very preterm(VPT) infants.
Methods: A total of 143 premature infants without retinopathy of prematurity were collected and then grouped according to body weight and gestational age. There were 130 full term infants in the control group. Infants about 1 year of age at risk for amblyopia were selected using Spot Vision Screener. Differences in amblyopia risk factors between full term infants and premature infants, between the LBW group and VLBW group, and between the PT group and VPT group were then analyzed.
Results: In terms of refractive status, diopter cylinder(DC) was higher in the premature infants than in full term infants; diopter sphere(DS) and spherical equivalent(SE) was higher in the VPT group than in the PT group. The prevalence of esotropia was higher in premature infants than in full term infants, and in the VPT group than in the PT group. As shown by the analysis, amblyopia risk factors were found in 10.5% premature infants vs. 3.9% full term infants, 4.7% LBW infants vs. 19.0% VLBW infants, and 5.1% PT infants vs. 16.9% VPT infants. All observed differences were statistically significant.
Conclusion: Based on the screening results, the incidence rate of amblyopia risk factors was higher in premature infants than in full term infants, and it was highest in both VPT infants and VLBW infants. The major risk factors were astigmatism and esotropia.
Knowledge, perception and attitude about climate change : A cross sectional study among general people in Bangladesh
Authors: Mosaddek Nafisa , Aman Md.Saklain 
Published: September 2022

Abstract
Bangladesh's topography makes it particularly susceptible to climate change. To tackle the impending tragedy of climate change, infrastructural, institutional, and financial capacity of the country must be increased. People's perception of climate change varies greatly based on their social backgrounds. Thus, understanding public perceptions of climate change may help improve government policies, adaption, and community activities. To understand Bangladeshi people's knowledge, perception, and attitude about climate change, an online survey among the general population was conducted using a structured questionnaire methodology. The study participants are mostly from Dhaka (70.25%) and have a moderate level of education (79.75% undergraduate). Most of them have heard of climate change and acknowledge the negative effects of climate change. Over half of participants are willing to give up personal gains to help solve current climatic and environmental issues. The majority of them, however, don't consider environmental factors while purchasing things and have never participated in climate change-related environmental protection initiatives. In Bangladesh, the general public's knowledge, attitude, and perception of climate change varies considerably. While knowledge and perceptions are high, attitude towards climate change is quite different. Along with promoting awareness, people should be encouraged to participate in climate change-related activities.
High Cell Density Cultivation (HCDC) of E. coli with Intensive Multiple Sequential Batches Together with
Fed-Batch at Cell Level (FBC) Superior to the Fed-Batch Technique
Authors: Chamsart Saethawat 
Published: September 2022

Abstract
High cell density cultivation (HCDC) is a technique that was developed and used in the cultivation of various microorganisms. Escherichia coli is the most prominent in the bacterial group and popular at the industrial scale for the production of bio-products. The HCDC conducted with the Fed-Batch modes is complicated. In this study, we developed a batch production medium (BPM), a minimal defined medium for industrial utilization with the potential use of dextrin at high concentrations as the major carbon source. Dextrin prevents cell cultivation system from the Crabtree effect due to its gradual hydrolysis to release glucose and gradual assimilation into E. coli cells like Fed-Batch at Cell Level (FBC). Yeast extract was added into the BPM to enhance cell growth. It was operated using 5-L bioreactors with the aerobic batch cultivation at high concentrations of dextrin, i.e., 90 g/L to achieve high-cell-density concentration at a high production rate superior to the Fed-Batch technique. Further, the Intensive Multiple Sequential Batch (IMFB) technique was developed to achieve a high yield at a high productivity. The maximum values of cell biomass, x; specific growth rate\(, \mu\); yield coefficient, Yx/s; productivity, rx; and efficiency (Ef) were 46.31 g/L, 0.54 h− 1, 0.55 g/g, 3.86 g/L/h and 98%, respectively. The results showed that cell cultivations and growth kinetics, biochemical engineering mass balances, and design of impeller speeds using fluid dynamics in the 5-L bioreactor of aerobic batch cell cultivation for the production of E. coli cell biomass a high-density concentration using dextrin to control the FBC at a high titer can be used for the scale-up of industrial bioreactors.
Vaccination Status and Long COVID Symptoms in Patients Discharged from Hospital
Authors: Nascimento Teresa Cristina D. C. , Costa Livia Valle , Ruiz Amanda Danieleto , Ledo Carla B. , Fernandes Valeria Paes Lima , Cardoso Luiz Francisco , Vieira José Mauro , Saretta Roberta , Kalil-Filho Roberto , Drager Luciano F. 
Published: September 2022

Abstract
Effective vaccination against coronavirus (COVID) mitigates the risk of hospitalizations and mortality but it is unclear whether the vaccination status may influence the post-COVID symptoms in patients who required hospitalization. The available evidence is limited to outpatients with mild cases. Here, we evaluated 412 patients (age: 60 ± 16 years, 65% males) consecutively admitted at two Hospitals in Brazil due to a confirmed case of COVID-19. As compared to patients with complete vaccination (n = 185) before infection/hospitalization, those with no/incomplete vaccination (n = 227) were younger and had a lower frequency of several comorbidities. Data during hospitalization revealed that the no/incomplete vaccination group required more admissions in the intensive care unit, used more corticosteroids and had higher rates of pulmonary embolism/deep venous thrombosis than the complete vaccination group. At 90 days after hospital discharge, patients with no/incomplete vaccination presented a higher frequency of ≥ 1 symptom than patients with complete vaccination: 40 vs. 27%; p = 0.013. After adjustments for confounders, no/incomplete vaccination (OR = 1.819; 95% CI:1.175–2.815), females (OR = 2.435; 95% CI:1.575–3.764) and intensive care unit admission during hospitalization (OR = 1.697; 95% CI:1.062–2.712) were independently associated with ≥ 1 symptom 90-days after hospital discharge. In conclusion, even in patients with more severe COVID-19 infection, vaccination mitigate the probability of long-COVID symptoms.