bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mepolizumab (Nucala)
Authors: CADTH  
Published: December 2022

CADTH recommends that Nucala should be reimbursed by public drug plans for the treatment of patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) if certain conditions are met.
Nucala should only be covered to treat adult patients with severe CRSwNP who have polyps on both sides of the nose, have already had at least 1 surgery to treat their nasal polyps or cannot have this type of surgery, and still have symptoms despite corticosteroid treatment for at least 3 months. When Nucala is first prescribed, physicians must submit a baseline Sino-nasal Outcome Test-22 (SNOT-22) score or endoscopy nasal polyp score so that response to treatment can be measured.
Nucala should only be reimbursed in patients whose nasal polyps are responding to treatment with Nucala and if it is prescribed by a physician with expertise in managing severe CRSwNP. The cost of Nucala must be lowered to be cost-effective and affordable.
La autoestima, su relación con el rendimiento académico y la deserción universitaria
Authors: Angulo Quiñonez Ariel Ángel 
Published: December 2022

El propósito principal de este artículo fue determinar la relación entre la autoestima, el rendimiento académico y la deserción universitaria de los estudiantes de segundo a sexto semestre de las diferentes carreras de la Facultad de la Pedagogía de la Universidad Técnica “Luis Vargas Torres” de Esmeraldas. Para la recolección de datos se realizó una encuesta a 200 alumnos y 20 docentes, por lo que se diseñó un instrumento de recolección de datos para determinar el nivel de autoestima, rendimiento académico y deserción de los estudiantes. Los resultados muestran que los hombres, a diferencia de las mujeres, se caracterizan por tener menos confianza en sí mismos, mientras que las mujeres tienden a resolver los problemas con más eficacia y rapidez, sin embargo, existe un porcentaje de estudiantes mujeres que tienen baja autoestima. Con base en lo anterior se propone, diseñar y aplicar estrategias para potenciar y fortalecer la autoestima a través de talleres que permitan el desarrollo integral y profesional, como parte de la formación de los estudiantes de tal forma que alcancen un rendimiento académico adecuado. También se debe tomar en cuenta el porcentaje de estudiantes que han desertado de las diferentes carreras, hacer el seguimiento respectivo para determinar las causas verdaderas de la deserción.
COVID-19 İle Değişen Müze Deneyimlerinin Turizm Coğrafyası Yaklaşımıyla Değerlendirilmesi: : Dünya'dan ve Türkiye'den Örnekler
Authors: OĞAN Okan , EMEKLİ Gözde 
Published: December 2022

Değişen sosyo-ekonomik ilişkiler, siyasi yapılanmalar, teknolojik gelişmeler, ulaşım ve haberleşme olanakları, salgın hastalıklar ve krizler hassas dinamiklere sahip olan turizmi ve coğrafya bağlamını etkilemektedir. 2019 yılının aralık ayında ortaya çıkan COVID-19, küresel bir krize dönüşmüş bu süreçte turizm ve kültürel mekanlar salgınla mücadelenin yollarını aramaya başlamıştır. Salgın sürecinde ulusal ve uluslararası ölçekte seyahat kısıtlamaları uygulanmış, ülkeler bir süreliğine izole bir yaşam tarzını uygulamak zorunda kalmıştır. Salgının ilk yılında turizm endüstrisi %72 oranında küçülerek 1990’lı yıllardaki durumuna gerilemiştir.
Küresel salgında müzeler; salgın krizinden çıkış stratejisi olarak sahip oldukları koleksiyonlarını ve etkinliklerini dijitalleştirerek sanal ortama taşımış, kendilerine olan ilgiyi canlı tutmaya çalışmıştır. Bu bağlamda araştırma, postmodernizmin etkisiyle gelişmeye başlayan ve salgınla birlikte yaygınlaşan sanal müzelerin turizm coğrafyası yaklaşımıyla değerlendirilmesini amaçlamaktadır. Çalışma, ilişkisel araştırma modeli çerçevesinde tasarlanmış, çeşitli kaynaklardan elde edilen ikincil veriler vasıtasıyla sanal müzelerin ulusal-uluslararası ölçekteki durumu arz-talep-mekânsal dağılım perspektifinde karşılaştırılmıştır. COVID-19 ile birlikte sanal mekanlara olan talebin artmasıyla başta Avrupa ve Kuzey Amerika ülkelerinde hızla yaygınlaşan sanal müzeler, milyonlarca ziyaretçiyi kendisine çekmeyi başarmıştır. Ayrıca salgın döneminde müzelerin sosyal medya aktivitelerindeki artış göze çarpmaktadır. Salgın sonrasında sanal müzelere yönelik talebin durumu ile küresel salgının sanal müzeler üzerindeki etkileri ise tartışılmaya devam etmektedir.
PENERAPAN BALANCE SCORECARD UNTUK MENGUKUR KINERJA PELAYANAN DI KEBUN BINATANG SURABAYA
Authors: Durjadi Durjadi  
Published: December 2022

Surabaya Zoo which was founded in 1916 experienced the effects of globalization in which the change occur very rapidly. Customer wants and needs (tourists) are constantly changing, science and technology that continues togrow and compatition among businesses pariwisaata an increasingly sharp, forcing the Surabaya Zoo to constantly improve its ability to provide travel services. The purposeof this study is to analyzee in depth how the implementation of the concept of balance scorecard to measure performance of the Surabaya Zoo. The concept of balance scorecard at the Surabaya Zoo includes four persepectives and the persepectives of four each-each have several strategic targets, performance measure and targets to be achieved. The four persepectives are : (1) Financial Persepective targeting strategy : increased surpluses, increased revenue, and cost reduction, performance measure used is the percentage increase in surplus, the precentage change in revenue and decrease costs. (2) Customer Persepective targeting strategies : the speed of service, quality relationship with the customer, the performance measure used is the throughput time, customer retention. (3) Internal Business Process Persepective with strategic objectives : incerased development and product marketing, performance measure used are service error rate, comparisons of the old infrastructure with new ones, the precentage of revenue from new products. (4) Learning and Growth Persepective with strategic objectives : increased employee productivity, increased commitment of personnal, the performance measure used is the percentage of employees who educated and trained, personnal satisfaction.
IMPLEMENTASI NILAI PALEMAHAN DALAM AJARAN TRI HITA KARANA TERHADAP HASIL PROJECT GAYA HIDUP BERKELANJUTAN DALAM KURIKULUM MERDEKA DI SMPN 1 UBUD
Authors: Ni Made Irma Wulandari  , I Made Sutajaya  
Published: December 2022

Konsep filosofis dalam Tri Hita Karana yakni palemahan adalah satu konsep filosofis dalam ranah keseimbangan. Konsep masyarakat Hindu Bali ini telah menjadi suatu konsep yang universal. Ketiga konsep dalam Tri Hita Karana tidak bisa dipisahkan dan berperan penting dalam Gaya Hidup Berkelanjutan. Pengelolaan lingkungan adalah sebuah langkah nyata dari penerapan Tri Hita Karana dengan konsep palemahan. Pengelolaan lingkungan ini dilaksanakan dengan tanggungjawab dan bagian perwujudan manusia yang memiliki tanggung jawab moral kepada Sang Pencipta. Kajian ini bertujuan untuk mendeskripsikan implementasi nilai palemahan dalam Tri Hita Karana terhadap Hasil Project Gaya Hidup Berkelanjutan salah satu tema wajib dalam Kurikulum Merdeka Mengajar, nilai filosofi THK diidentifikasi mengandung muatan nilai keberlanjutan dan bisa dijadikan sebagai pijakan pengembangan sustainable konsep di lingkungan sekolah. Nilai keberlanjutan yang menjadi dasar dalam menentukan pengembangan sustainable di lingkungan sekolah terkandung dalam konsep THK yakni mencakup aspek sosial, aspek budaya dan aspek ekologi dalam masyarakat. Konsep ini juga dapat diterapkan di daerah lain maupun negara lain sebagai dasar pengembangan sekolah sesuai dengan budaya setempat dan ajaran agama masing-masing. Hal ini karena setiap ajaran agama umumnya mengajarkan kita untuk senantiasa menjaga alam, melestarikan alam dan bersahabat dengan alam. Penelitian kepustakaan yang dilakukan dengan membaca, menganalisis, dan mensintesis hasil penelitian dan kajian-kajian resmi dokumen negara yang telah diterbitkan secara online adalah metode yang digunakan dalam kajian ini. Data yang diperoleh kemudian dianalisis dengan pendekatan tematik. Adanya koherensi antara nilai-nilai palemahan terhadap hasil belajar project gaya hidup berkelanjutan yang digaungkan sebagai program wajib nasional dalam kurikulum merdeka mengajar adalah dasar kajian ini. Kajian ini juga membuka peluang untuk menguji temuan penelitian kepustakaan ini berdasarkan data empiris bagi penelitian lebih lanjut.
Kinerja Dinas Ketenagakerjaan Kabupaten Agam dalam Penanggulangan Pengangguran di Kabupaten Agam
Authors: Dara Rizkita Alamanda  , Harapan Tua RFS  
Published: December 2022

Masalah ketenagakerjaan merupakan permasalahan yang kompleks di Kabupaten Agam, salah satunya permasalahan pengangguran. Pengangguran harus ditanggulangi demi mencapai kesejahteraan rakyat. Penyebab pengangguran du Kabupaten Agam adalah kurangnya penyerapatan tenaga kerja dan inovasi kualitas sumber daya ketenagakerjaan yang belum memadai. Dinas Ketenagakerjaan Kabupaten Agam merupakan salah satu instansi yang berperan penting dalam penanggulangan pengangguran di Kabupaten Agam. Penelitian bertujuan untuk mengetahui kinerja Dinas Ketenagakerjaan Kabupaten Agam dalam penanggulangan pengangguran di Kabupaten Agam. Konsep teori dalam penelitian ini yaitu kinerja organisasi oleh Agus Dwiyanto 2008. Metode penelitian ini yaitu metode penelitian kualitatif dengan pendekatan deskriptif melalui kegiatan wawancara, observasi dan dokumentasi. Hasil penelitian yaitu dalam pelaksanaan kinerja Dinas Ketenagakerjaan Kabupaten Agam dalam penanggulangan pengangguran di Kabupaten Agam masih terdapat hambatan dalam pelayanannya seperti kurangnya penyerapan tenaga kerja, kurangnya keahlian sumber daya manusia, anggaran, sarana dan prasarana yang belum memadai dan pelatihan ketenagakerjaan yang belum maksimal.
The Clarendon Edition of the Works of John Locke
Authors: Goldie Mark 
Published: December 2022

It has been some years since Locke Studies published an update on the Clarendon Edition. The current state of the Edition is given here. Two volumes will appear within the next eighteen months: J. R. Milton’s edition of the Abridgements of the Essay and Mark Goldie’s edition of The Correspondence of John Locke, vol. 9, Supplement.
PEMBAYARAN PANJAR PADA PERJANJIAN JASA RIAS PENGANTIN AKIBAT PANDEMI COVID-19 (SUATU PENELITIAN DI RUMANTI MAKEOVER KOTA LHOKSEUMAWE)
Authors: Iza Zaya Iza Zaya , Wardah Wardah 
Published: December 2022

Pasal 1464 KUHPerdata menjelaskan bahwa jika pembelian dilakukan dengan memberi uang panjar, maka salah satu pihak tak dapat membatalkan pembelian itu dengan menyuruh memiliki atau mengembalikan uang panjarnya. Pemerintah Indonesia melalui Keppres No.12 tahun 2020 menetapkan Covid-19 Sebagai Bencana Nasional. Penelitian ini mengkaji hak dan kewajiban para pihak, bentuk penerapan risiko panjar dan penyelesaian yang dilakukan para pihak yang timbul akibat perjanjian jasa rias pengantin akibat Covid-19. Hasil penelitian menunjukkan bahwa hak dan kewajiban para pihak yang telah membayar panjar pada perjanjian jasa rias pengantin akibat pandemi Covid-19 yaitu pengguna jasa memenuhi pembayaran dan penyedia jasa melakukan jasa rias. Adapun penerapan resiko antara para pihak yaitu saling menanggung kerugian. Upaya penyelesaian pada perjanjian rias pengantin yang telah membayar panjar akibat pandemi Covid-19 yaitu pemberlakuan panjar yang telah dibayarkan berlaku selama nya dalam bentuk panjar.
PENERAPAN LEMBAR KERJA SISWA MENGGUNAKAN METODE PETA PIKIRAN TERHADAP PERSEPSI DAN HASIL BELAJAR SISWA
Authors: Rambe Imelda Wardani 
Published: December 2022

Penelitian ini bertujuan untuk mendeskripsikan efektivitas lembar kerja siswa menggunakan metode peta pikiran terhadap persepsi dan hasil belajar siswa. Penelitian ini menggunakan tipe penelitian deskriptif dengan pendekatan kuantitatif. Lembar Kerja Siswa yang digunakan merupakan hasil pengembangan perangkat pembelajaran menggunakan model pengembangan 4D pada penelitian peneliti sebelumnya. Pada penelitian ini telah dilaksanakan tahap penyebaran produk peneliti sebelumnya yaitu lembar kerja siswa yang telah valid. Lembar Kerja Siswa diterapkan ke lapangan untuk melihat efektivitasnya. Penerapan Lembar Kerja Siswa menggunakan metode peta pikiran dilakukan pada siswa kelas VII MTs Bayu Pertiwi Sunggal. Instrumen penelitian berupa angket respon siswa, angket persepsi siswa dan tes ketuntasan belajar siswa. Dari hasil penerapan di peroleh bahwa: lembar kerja siswa menggunakan metode peta pikiran yang diterapkan efektif dilihat dari (1) ketuntasan belajar klasikal siswa terpenuhi, (2) persepsi siswa terhadap pembelajaran dalam kategori tinggi (positif) dan (3) respon siswa terhadap pembelajaran positif. Kata Kunci: Lembar Kerja Siswa, Peta Pikiran, Persepsi, Hasil Belajar
PERLINDUNGAN HUKUM BAGI KREDITUR ATAS SAHAM TANPA WARKAT (SCRIPLESS) SEBAGAI OBJEK JAMINAN GADAI
Authors: Waladi Fathira Tri , Susiana S 
Published: December 2022

Scripless shares are one of the objects of collateral as regulated in article 60 section (2) of UUPT. Collateral provides guarantee for repayment of debts to creditors as regulated in article 1150 of the Indonesian civil code. Yet, scripless shares collateral is different from general collateral, where the object of collateral is not on the creditor, and the value of shares changes anytime. This study aims to explain the legal protection for the creditor on scripless shares collateral. Based on findings, the author found that the current regulations have not yet provided maximum legal protection for the creditor in the scripless shares collateral system. KSEI only acts as the depositor of the collateral object and not obliged to guarantee the fulfillment of the creditor’s rights. Thus, when the blocking of collateral shares is lifted, KSEI does not have to ensure that the rights of creditors have been fulfilled. Based on the findings, the author suggests a regulation that obliges KSEI to ensure the creditor’s rights have been fulfilled to be made, before unblocking the collateral objects.
Ending the Oppression Olympics: Promoting the Concomitant Political Participation of Marginalised Groups in Kenya
Authors: Thuo Luciana 
Published: December 2022

The 2010 Constitution of Kenya is laudable for its commitment to redressing the exclusion from political and public life experienced by marginalised groups. Articles 21 and 27 require that the state and public officials take legal and administrative measures to ensure marginalised groups’ participation in governance and other spheres of life. Moreover, Article 100 mandates the passing of a single legislation to provide for the representation in Parliament of women, youths, persons with disabilities, ethnic minorities and marginalised communities. These provisions evince an intention that their inclusion be redressed simultaneously.
However, the equality debate appears to have become synonymous with gender equality or the implementation of the ‘two-thirds gender rule’ as it is popularly known. This rule requires that not more than two-thirds of any elective or appointive position be occupied by one gender. Women’s underrepresentation has dominated litigation on inclusion, academic writing and proposals for electoral reforms.
This unitary approach to inclusion, which privileges one category of difference, makes other marginalised groups doubly invisible. Moreover, statistics demonstrate that despite privileging gender over other factors of exclusion, women’s participation remains marginal. Further, it causes the groups at the bottom to compete rather than cooperate, while still falling short of addressing the informal patterns of prejudice and discrimination that keep the majority of the marginalised on the fringes of public life.
This research proposes the intersectionality approach to policy design to simultaneously promote political participation of the various groups. Intersectionality recognises the role of the various categories of difference as equally important yet conceptually different, examines the relationship between the various categories, and emphasises the interaction between individual and institutional factors in achieving equality. Intersectionality, therefore, provides the most effective approach to diagnosing the factors fuelling exclusion and ultimately providing an effective prescription.
Model of pedagogical support for the formation of professional and pedagogical identity of students
Authors: Холопова Е.С. , Котова С.С. 
Published: December 2022

Представленная в статье модель педагогического сопровождения является результатом первого, теоретического, этапа исследования, посвященного изучению специфики формирования профессиональной идентичности у будущих педагогов профессионального образования.
The model of pedagogical support presented in the article is the result of the first, theoretical, stage of research which is aimed at studying the specifics of the formation of professional identity among future teachers of vocational education.
The Role of Continuance Intention, e-wallet Applications Users for Transaction Multi-payments in Indonesia
Authors: Unarto Tirto , Suhud Usep , Rizan Mohamad 
Published: December 2022

The study examines the effect of perceived ease of use, perceived usefulness and trust on continuance intention on e-wallets users in Indonesia with customer satisfaction and habit as intervening variables. This research also aims to see variable continuance intention in users transactions multi-payment e-wallet as cashless program supported the government in Indonesia. The research used was a quantitative method with data obtained from as many as 216 participants distributed online. The sampling technique purposive sampling, this reseacrh used structural equation modeling (SEM) using SPSS 26 and AMOS 23 software. The results of this study, perceived ease of use has a positive and insignificant effect on customer satisfaction, Perceived usefulness has a positive and insignificant effect on customer satisfaction, trust has a positive and significant effect on customer satisfaction, customer satisfaction has a positive and significant effect on continuance intention, customer satisfaction has a positive and significant effect on habit, and habit has a positive and significant effect on continuance intention.
Association of Serum Vitamin D level and COVID-19 infection: A Case-control Study
Authors: Abdrabbo AlYafei Najat , Fathima Jaleel Bushra Naaz , Abdel-Salam Abdel-Salam G. , Ali Al-Saadi Hamda , Al Abdulla Samya Ahmad 
Published: December 2022

Background: Vitamin D is considered a potent modulator of the immune system, albeit its role in COVID-19 infection is a matter of debate. The present study aimed to estimate the association between serum vitamin D levels and COVID-19 among people in Qatar.
Methods: This case-control study, approved by the Institutional Review Board of Primary Health Care Corporation (PHCC) Qatar, retrospectively evaluated the principal public healthcare sector population data repository retrieved from the cloud-based Electronic Health Record (EHR) software-Cerner, during April 2020–2021. The health records of all adult patients aged >18 years who had undergone the reverse transcription-polymerase chain reaction (RT-PCR) test and whose medical records had documented serum 25-hydroxyvitamin D [25 (OH)D] levels were analyzed.
Results: A total of 924,173 EHRs were extracted, of which 62,451 EHR comprised of 16,446 (26.3%) COVID-19 patients and 46,005 (73.7%) negative-control group patients met the inclusion criteria. The odds ratio (OR) among different categories of vitamin D deficiency (VDD) revealed that people with mild/moderate VDD were 1.18 times (95% CI 1.126–1.258) and those with severe VDD were 1.90 times (95% CI 1.116–1.251) more likely to have COVID-19 infection when compared to the people with optimal serum vitamin D level. On applying multiple logistic regression, the odds of having COVID-19 infection were found to be 1.27 times (95% CI 1.184–1.371) higher among those with mild/moderate VDD and 1.32 times (95% CI 1.206–1.405) higher among those with severe VDD when compared to people with optimal vitamin D level (p < 0.001).
Conclusion: Our findings demonstrated a significant association between the suboptimal serum vitamin D level and COVID-19 infection. Further studies are required to determine the effects of VDD on the severity and outcomes of COVID-19 infections.
A STUDY OF GREEN INDEPENDENT VILLAGES IN ECONOMIC ASPECTS IN THE SPECIAL REGION OF YOGYAKARTA
Authors: Sugiyanto Sugiyanto , Tiurmida Nelly , Triono Tomi Agus 
Published: December 2022

Independent green village is a village that can develop and enhance their institutional capacity by persevering their tradition, local wisdom, and knowledge. This village is expected to be able to develop their economical products that are based on natural resources and is managed sustainably so that it can be a way to maximize the village’s prosperity.
This study uses qualitative exploratory research with Strength, Weakness, Opportunity, and Threat (SWOT) as its analytical tool. The data are gathered with four techniques, that is observation, interview, documentation study, and Focus Group Discussion (FGD). Informants are determined interactively and continuously so that it produces saturated data.
The result of this exploratory study found that people and the natural environment in the economic sector are united and are interrelated. Hence, the economic access of the independent green village can improve the natural resources quality through community empowerment, skill development, knowledge on entrepreneurship improvement, and expanding business relationship through driving figures like innovator that has concern regarding people to improve and diversify local resources-based products.
THE INFLUENCE OF COMPENSATION, MOTIVATION, WORK ENVIRONMENT, AND WORK DISCIPLINE ON JOB SATISFACTION
Authors: Haholongan Rutinaias , Elviayuliana Elviayuliana 
Published: December 2022

This study aims to understand the effect of compensation, motivation, work environment and work discipline on job satisfaction in home and personal care companies. The method used in this research is survey research. The population in this study is all working people. The samples in this study were 78 respondents. The data analysis method used is statistical analysis of descriptive data and analysis of respondents' answers. Statistical analysis methods can be selected and adapted to the research objectives. Calculations using the SPSS program version 25.00 with the coefficient of determination and hypothesis testing (t test).
The results of the t test show that the compensation variable has no effect on job satisfaction. Motivational variables affect job satisfaction. Work environment variables affect job satisfaction. The work discipline variable influences job satisfaction.