bluuebunny/crossref_metadata_2025_split huggingface dataset:
Main group cyanides: from hydrogen cyanide to cyanido-complexes
Authors: Schulz Axel , Surkau Jonas 
Published: September 2022

Abstract
Homoleptic cyanide compounds exist of almost all main group elements. While the alkali metals and alkaline earth metals form cyanide salts, the cyanides of the lighter main group elements occur mainly as covalent compounds. This review gives an overview of the status quo of main group element cyanides and cyanido complexes. Information about syntheses are included as well as applications, special substance properties, bond lengths, spectroscopic characteristics and computations. Cyanide chemistry is presented mainly from the field of inorganic chemistry, but aspects of chemical biology and astrophysics are also discussed in relation to cyano compounds.
Radiation error of air temperature measurements: Minimization of the error by a new reference system and comparison with conventional measurement systems, diurnal and annual variation of their errors as a function of radiation and wind speed
Authors: Miegel Konrad , Fröhlich Thomas , Pätz Joachim 
Published: September 2022

Abstract
The measurement of air temperature is associated with inaccuracies resulting from radiation errors. Liquid thermometers and automatic sensors are therefore housed in screens. Mechanical ventilation also helps to increase the accuracy of readings. Nonetheless, temperature measurements are not completely accurate. This spurred the development of a measuring system that features improved radiation protection and a modified mechanical ventilation system through a new type of screen. Parallel measurements with this new measurement system and two conventional screens of multiple plastic cones were taken at a location in north-east Germany with a temperate climate. Of the two traditional screens, one was ventilated and the other not. Based on previous findings concerning the seasonality of radiation errors, our analysis of their dependency on global radiation and wind speed was focused on the months of May to August, when global radiation is at its strongest. It was found that the not insignificant differences in

Δ
T

\Delta T

display a characteristic diurnal variation. With the new measurement system, in comparison with the two conventional measurung systems, the average air temperature of the four surveyed months during daylight hours was 0.43 K and 0.58 K lower. The differences in

Δ
T

\Delta T

are greatest not in the middle of the day but when the sun is low in the sky, as radiation is then reflected into the screen. The findings contribute to the understanding of the temporal variability of radiation errors in modern weather stations in dependence on global radiation and wind speed. The technical innovations presented here allow radiation errors to be largely avoided.
Ketamine alleviating depressive-like behaviors is associated with regulation of nNOS–CAPON–Dexras1 complex in chronic unpredictable mild stress rats
Authors: Shen Yiwei , Lv Feng , Min Su , Hao Xuechao , Yu Jian 
Published: September 2022

Abstract

Background
A growing number of studies have demonstrated that ketamine induces rapid and sustained antidepressant action. Neuronal nitric oxide synthase (nNOS) signaling has been explored for the treatment of neuropsychiatric disorders for decades. But the effect of ketamine on nNOS signaling is poorly understood. The aim of the present study was to investigate the effect of ketamine on nNOS signaling in a chronic unpredictable mild stress (CUMS) model of depression.

Methods
Forty-eight rats were randomly divided into four groups: the control group of healthy rats (group C), the healthy rats treated with ketamine 10 mg/kg for 3 days (group CK), the rats model of stress-induced depression group (group D), and the depressed group treated with ketamine 10 mg/kg for 3 days (group DK). The sucrose preference test and open field test were used to assess behavioral changes. Immunohistochemistry, immunofluorescence, and real-time PCR analysis were carried out to measure the expression of nNOS, CAPON, and Dexras1 in the prefrontal cortex (PFC) of the CUMS rats.

Results
Compared with healthy rats, the total distance traveled, the rearing counts, the sucrose preference percentage (SPP), and CAPON and Dexras1 expression in the PFC significantly decreased, while nNOS expression increased in CUMS rats. After treating with ketamine, the total distance traveled, the rearing counts, the SPP, and CAPON and Dexras1 expression significantly increased, while nNOS expression significantly decreased.

Conclusion
The results indicated that ketamine improved the depressive behavior of rats, which may be related to the reduced nNOS expression and enhanced CAPON and Dexras1 expression.
Optimization Algorithm of Reinforcement Point Location of New Lightweight Concrete Material for Building Exterior Wall
Authors: Gao Jingyang 
Published: September 2022

Abstract
Current methods for predicting the location of reinforced concrete materials neglect the precise division of material damage areas, resulting in poor prediction accuracy of the location of reinforced concrete. Therefore, a new optimization algorithm for the location of reinforcing points of new lightweight concrete materials for building exterior walls is proposed. The damage area of lightweight concrete is divided into several zones by using the precise threshold method. Based on the least squares support vector machine, the crack location on the surface of the new lightweight concrete wall is predicted. By solving the coordinates of each point of the triangle, the active reinforcement of the surface cracks of the new lightweight concrete wall materials is realized. The experimental results show that the proposed method takes less time and the prediction accuracy of the reinforced point position of the new lightweight concrete material is higher.
The Possibility of Producing Uniform Nanofibers from Blends of Natural Biopolymers
Authors: Abdulkadhim Mushreq Kareem , Habeeb Salih Abbas 
Published: September 2022

Abstract
This study was designed for the fabrication, characterization, and optimization of electrospinning blending three natural biopolymers including gelatin:chitosan:sodium alginate (G:CS:SA) solutions. Series of pure gelatin, 80:10:10, 60:20:20, 40:30:30, and 20:40:40 ratios of blends (G:CS:SA) were dissolved in aqueous acetic acid. The effects of solution property parameters blends were investigated through evaluation of the electrical conductivity, viscosity, and surface tension. The morphological properties of bio-nanofibers were studied using field-emission scanning electron microscopy to determine the diameter, bead formation, and the nanofiber distribution. The results showed that the increase in the percentage ratio of CS with SA higher than 40 % in G:CS:SA caused a decrease in polymer viscosity, average fiber diameter, and bead formation. The nanofibers produced from blending ratio 80:10:10 G:CS:SA had a uniformity and low numbers of bead formation. On the other hand, X-ray diffraction showed a higher crystallinity percentage and crystalline size for the aforementioned ratio; in addition, the Fourier-transform infrared showed interactions among the molecules of G, CS, and SA in nanofibers.
Comparison of Early-Onset Sepsis Risk-Stratification Algorithms in Neonates in a Kenyan Nursery
Authors: Fileccia Lindsey , Wood Tristan , Guthrie Alyssa , Ronoh Cynthiah , Sleeth Clark , Kamath-Rayne Beena D. , Liu Chunyan , Schaffzin Joshua K. , Rule Amy RL. 
Published: September 2022

BACKGROUND AND OBJECTIVES
Risk stratification algorithms (RSAs) can reduce antibiotic duration (AD) and length of stay (LOS) for early-onset sepsis (EOS). Because of higher EOS and antibiotic resistance rates and limited laboratory capacity, RSA implementation may benefit low- and middle-income countries (LMIC). Our objective was to compare the impact of 4 RSAs on AD and LOS in an LMIC nursery.

METHODS
Neonates &lt;5 days of age admitted for presumed sepsis to a Kenyan referral hospital in 2019 (n = 262) were evaluated by using 4 RSAs, including the current local sepsis protocol (“local RSA”), a simplified local protocol (“simple RSA”), an existing categorical RSA that uses infant clinical examination and maternal risk factors (CE-M RSA) clinical assessment, and the World Health Organization’s Integrated Management of Childhood Illness guideline. For each RSA, a neonate was classified as at high, moderate, or low EOS risk. We used к coefficients to evaluate the agreement between RSAs and McNemar’s test for the direction of disagreement. We used the Wilcoxon rank test for differences in observed and predicted median AD and LOS.

RESULTS
Local and simple RSAs overestimated EOS risk compared with CE-M RSA and the Integrated Management of Childhood Illness guideline. Compared with the observed value, CE-M RSA shortened AD by 2 days and simple RSA lengthened AD by 2 days. LOS was shortened by 4 days by using CE-M RSA and by 2 days by using the local RSA.

CONCLUSIONS
The local RSA overestimated EOS risk compared with CE-M RSA. If implemented fully, the local RSA may reduce LOS. Future studies will evaluate the prospective use of RSAs in LMICs with other interventions such as observation off antibiotics, biomarkers, and bundled implementation.
Improving Student's Reasoning Ability Through The Tahfizh Al-Qur’an Program
Authors: Chalida Sri , Syafruddin Syafruddin , Pinto Nandi , Fakhruddin Muhammad Irhash 
Published: September 2022

Teaching tahfizh al-Quran is one way to build student competence to do reasoning in and memorizing the Al-Qur’an. Given the changes in vision and mission as stated in the competency-based curriculum, it is necessary to make concrete efforts to prepare and make its implementation successful. This study aims to identify the teaching method of tahfizh al-Quran at the Tafsir Hadis Major, to explain the strategy of optimally developing tahfizh al-Qur'an so that it can improve students' reasoning abilities and identify the level of students' reasoning ability after participating in the tahfizh al-Qur'an program at the Tafsir Hadis Major. This study is a development activity carried out in collaboration between students and lecturers to conceptually design the design of teaching materials based on experience and existing conditions. These two stages will always be accompanied by a process of evaluation and reflection to improve the designs developed. This research shows that first; the sima'i method is a method that is widely used by students in memorizing the Qur'an, secondly; the strategy of fostering tahfizh al-Quran should be done with the muraja'ah method, Third; From the results of the calculation of the student's reasoning ability test scores, the average score of students' reasoning abilities in the high category was 48.82, the average category was 41.06, and the low category has obtained an average of 39. These different average gains indicate that the levels of students' reasoning abilities are different.
METODE EXPONENTIAL SMOOTHING WITH TREND PADA AKURASI PERAMALAN KEBAKARAN HUTAN DAN LAHAN
Authors: Pratiwi Merina , Syarief Amiroel Oemara 
Published: September 2022

Kebakaran hutan dan lahan yang terjadi membuat dampak global mengakibatkan gangguan pernapasan dan mengganggu aktivitas sehari-hari. Pemerintah sedang berupaya mengatasi permasalahan tersebut, namun belum dapat sepenuhnya menentukan area kebakaran hutan dan lahan. Penelitian ini bertujuan untuk meramalkan kebakaran hutan dan lahan menggunakan metode exponential smoothing with trend. Hasil penelitian menunjukkan bahwa akurasi peramalan dengan metode Exponential Smoothing with Trend menggambarkan tingkat kesalahan yang cukup berdasarkan kriteria, dengan memiliki MAPE yang lebih kecil sebesar 30,99 sehingga metode ini merupakan salah satu metode peramalan yang cocok untuk meramalkan luas kebakaran hutan dan lahan tahun 2023 dengan luas sebesar 167,487 Hektare. Hasil perhitungan ini dapat dijadikan sebagai dasar kebijakan dalam pemberian informasi dan penanganan dini luas daerah yang terkena dampak kebakaran hutan dan lahan pada tahun 2023.
Penyelenggaraan Umrah Dalam Perspektif Hukum Perlindungan Konsumen Pasca PMA No. 8 Tahun 2018
Authors: Suwandono Agus , S. Dajaan Susilowati 
Published: September 2022

To give better protection to the prospective participant of the Islamic pilgrimage (‘umrah), the Minister of Religious Affairs has just added consideration to the Consumer Protection Law in enacting the Minister of Religious Affairs’ Regulation No. 8 of 2018. According to the Consumer Protection Law, this research studies the qualification of the Islamic Pilgrimage’s prospective participant and organizer. It also looks at the recourse obtained by the prospective participants from the perspective of the consumer protection law, after the enactment of the Minister of Religious Affairs’ Regulation No. 8 of 2018. This research is using a juridical-normative approach by specifying the study in a descriptive-analytical manner. The result shows that the Consumer Protection Law’s provision qualifies the prospective participant of Islamic pilgrimage (‘umrah) as a consumer, whereby its organizer as a business actor. From the perspective of the Consumer Protection Law, the enactment of the Minister of Religious Affairs’ Regulation No. 8 of 2018 has not yet fully safeguarded the prospective participant’s interests. In conclusion, after bearing into mind that their rights have not yet wholly fulfilled, particularly at the time of departure cancellation.

Pemberlakuan PMA No. 8 Tahun 2018 dengan mempertimbangan ketentuan Undang-Undang Perlindungan Konsumen merupakan hal baru diharapkan dapat lebih memberikan perlindungan terhadap calon jemaah umrah. Penelitian ini mengkaji bagaimanakan kualifikasi calon jemaah umrah serta PPIU berdasarkan Undang-Undang Perlindungan Konsumen serta bagaimanakah perlindungan calon jemaah umrah dalam perspektif perlindungan konsumen pasca pemberlakuan PMA No. 8 Tahun 2018. Penelitian ini merupakan penelitian yurudis normatif dengan spesifikasi penelitian deskriptif analitis. Hasil penelitian menunjukkan bahwa calon jemaah umrah dapat dikualifikasikan sebagai konsumen dan PPIU juga dapat dikualifikasikan sebagai pelaku usaha berdasarkan Ketentuan Undang-Undang Perlindungan Konsumen. Perlindungan calon jemaah umrah dalam perspektif perlindungan konsumen pasca pemberlakuan PMA No. 8 Tahun 2018 belum sepenuhnya memberikan perlindungan bagi calon jemaah umrah, mengingat pemenuhan akan hak-hak para calon jemaah umrah tidak dapat terpenuhi terlebih dalam hal terjadinya gagal berangkatnya calon jemaah umrah.
Relationships of age of menarche, frequency and duration of kunyit asam consumption and dysmenorrhea
Authors: Prasetyowati Sebrina Andri , Surjadi Lily Marliany 
Published: September 2022

Latar belakang : Dismenore adalah kondisi nyeri perut yang terjadi pada saat haid, dan banyak terjadi khususnya pada remaja. Faktor pencetusnya adalah adanya kontraksi otot uterus yang berlebihan akibat dilepaskannya prostaglandin. Kunyit asam merupakan suatu ramuan yang telah lama digunakan untuk mengurangi nyeri saat haid. Ramuan ini mengandung berbagai senyawa aktif yang memiliki efek anti inflamasi, antioksidan dan analgetika yang diketahui dapat menghambat produksi prostaglandin dengan cara menghambat aktivitas enzim COX-2.
Metode : Penelitian ini dilakukan dengan metode potong lintang pada 108 pelajar putri SMP Yayasan Indocement - Bogor. Data diperoleh dengan menggunakan kuesioner FFQ untuk mengetahui frekuensi dan durasi konsumsi kunyit asam, dan NRS untuk menentukan skala nyeri pada dismenore.
Hasil : data menunjukkan bahwa usia menarche tidak berhubungan dengan kejadian dismenore, sedangkan frekuensi dan durasi konsumsi kunyit asam berhubungan dengan kejadian dismenore
Kesimpulan : Tidak terdapat hubungan antara usia menarche dengan kejadian dismenore (p=0.348). terdapat hubungan yang bermakna antara frekuensi dan durasi konsumsi kunyit asam dengan kejadian dismenore (p=0.016 dan 0.007)
Kata kunci : dismenore, usia menarche, kunyit asam, frekuensi, durasi
The ANALYSIS OF THE DAMAGE LEVEL AND COST ESTIMATE MAINTENANCE OF FACULTY OF NURSING UNIVERSITY OF JEMBER
Authors: Oktavia Helda Frista , Suyoso Hernu , Hayati Nunung Nuring 
Published: September 2022

The Jember University Faculty of Nursing building is on the Tegal Boto campus of Jember University, which was built in 2008 for the Dekanat building and 2010 for the laboratory building so that it can be seen that the age of the Faculty of Nursing building has reached more than 10 years. Therefore it is necessary to evaluate and evaluate the condition of the building by analyzing the level of damage and calculating maintenance costs. This study uses the Analytical Hierarchy Process (AHP) method with the Expert Choice version 11 assistance program. The analysis process of the Dekanat’s building produced 16 elements that were slightly damaged and 8 other elements were in good condition. Whereas for the laboratory building there were 11 elements that suffered minor damage and 10 other elements had good conditions. The condition index value for the Dekanat building is 99.73% and the laboratory building is 98.49%, both of which are included in the Zone 1 Building Condition Index between 85% - 100% which has excellent conditions. The highest priority in maintenance and maintenance is in the exterior wall ceramic element components and the lowest priority is in the shutters component. So that the total cost required in the care and maintenance of the Dekanat building is Rp. 26,119,595.05 and for the laboratory building Rp. 48,513,395.38.
Bangunan gedung Fakultas Keperawatan Universitas Jember berada di kampus Tegal Boto Universitas Jember yang dibangun pada tahun 2008 untuk gedung dekanat dan 2010 untuk gedung laboratorium, sehingga dapat diketahui bahwa umur bangunan gedung Fakultas Keperawatan telah mencapai 10 tahun lebih. Oleh karena itu diperlukan adanya evaluasi dan penilaian kondisi bangunan dengan menganalisa tingkat kerusakan dan menghitung biaya pemeliharaan. Penelitian ini menggunakan metode Analytical Hierarchy Process (AHP) dengan program bantu Expert Choice versi 11. Proses analisa terhadap gedung dekanat menghasilkan 16 elemen mengalami kerusakan ringan dan 8 elemen lainnya mempunyai kondisi baik. Sedangkan untuk gedung laboratorium terdapat 11 elemen mengalami kerusakan ringan dan 10 elemen lainnya mempunyai kondisi baik. Nilai indeks kondisi untuk gedung dekanat sebesar 99.73% dan untuk gedung laboratorium sebesar 98.49%, keduanya masuk dalam Indeks Kondisi Bangunan Zona 1 antara 85% - 100% yang mempunyai kondisi baik sekali. Prioritas tertinggi dalam pemeliharan dan perawatan terdapat pada komponen elemen keramik dinding eksterior dan prioritas terendah terdapat pada komponen daun jendela. Sehingga total biaya yang diperlukan dalam perawatan dan pemeliharaan untuk gedung dekanat sebesar Rp. 26,119,595.05 dan untuk gedung laboratorium sebesar Rp. 48,513,395.38.
Desain Ulang Dinding Penahan Tanah Menggunakan Dinding Diafragma dan Angkur pada Tanah Lunak (Studi Kasus: Grand Dharmahusada Lagoon)
Authors: Maharani Tiara , Nurtjahjaningtyas Indra , Wicaksono Luthfi Amri 
Published: September 2022

In some cases, basement wall work still often occurs as a construction failure with a variety of causes. One of them is a basement construction project for an apartment and mall in Grand Dharmahusada Lagoon. The first plan of the basement wall didn’t strong enough to resist a lateral movement of the soil. The previous studies have been carried out by redesigning the retaining wall using a diaphragm wall and ground anchor as a support system. The results are obtained that the use of diaphragm walls can decrease the value of displacement that occurs on the wall. However, previous studies have only conducted a review of the diaphragm wall thickness. This study adds several numbers of anchors as research variables to find effective and efficient combinations. This study compares the effect of diaphragm wall dimensions with a different number of anchors on the deformation value and safety factor. Based on the results of the study, a wall thickness of 1.75 m with a depth of 33 m using 3 anchors a deformation occurred are 3.63 m while using 4 anchors a deformation occurred are 2.37 m. The difference in deformation is 1.26 m. Because the value of deformation was still large, it carried out a re-design for the anchor position, and diaphragm wall dimension with the same number of anchors, and the deformation results were reduced to 15.81 cm with a safety factor of 1.3.
ABSTRAK
Pada beberapa kasus, pekerjaan dinding basement masih sering mengalami kegagalan konstruksi dengan berbagai macam penyebab. Salah satu diantaranya pada proyek pekerjaan dinding basement apartemen dan mall Grand Dharmahusada Lagoon. Dinding basement yang direncanakan diawal ternyata tidak cukup kuat untuk menahan pergerakan lateral tanah. Telah dilakukan pada penelitian sebelumnya dengan merencanakan ulang dinding penahan tanah menggunakan dinding diafragma dan sistem penunjang angkur tanah. Kemudian didapatkan hasil yaitu penggunaan dinding diafragma mampu memperkecil displacement yang terjadi pada dinding. Namun penelitian sebelumnya hanya melakukan tinjauan pada ketebalan dinding diafragma. Penelitian ini menambahkan jumlah angkur sebagai variabel penelitian untuk mencari kombinasi yang efektif dan efisien. Penelitian ini membandingkan pengaruh penggunaan dimensi dinding diafragma dengan jumlah angkur yang berbeda terhadap nilai deformasi dan faktor keamanan. Berdasarkan hasil analisa menggunakan PLAXIS V8.6, pada ketebalan dinding 1,75 m dengan kedalaman 33 m menggunakan 3 angkur terjadi deformasi sebesar 3,63 m sedangkan dengan penggunaan 4 angkur terjadi deformasi 2,37 m. Selisih deformasi yang terjadi sebesar 1,26 m. Direncanakan ulang untuk penempatan angkur, dimensi dinding pada jumlah angkur yang sama maka didapatkan hasil deformasi berkurang hingga 15,81 cm dengan faktor keamanan 1,3.
Early-life origin of prostate cancer through deregulation of miR-206 networks in maternally malnourished offspring rats
Authors: Portela Luiz , Constantino Flavia , Camargo Ana , Santos Sergio , Colombelli Ketlin , Fioretto Matheus , Barata Luisa , Silva Erick , Scarano Wellerson , Moreno Carlos , Justulin Luis A 
Published: September 2022

Abstract
The Developmental Origins of Health and Disease (DOHaD) concept has provided the framework to assess how early life experiences can shape health and disease throughout the life course. While maternal malnutrition has been proposed as a risk factor for the developmental programming of prostate cancer (PCa), the molecular mechanisms remain poorly understood. Here, we found an association between deregulation of steroidogenesis and impairment of the ventral prostate (VP) growth in young offspring rats exposed to maternal low protein diet (LPD) during gestation and lactation. Reanalysis of RNA-seq data demonstrated that miR-206 was upregulated in the VP of young maternally malnourished offspring. Target prediction and in vitro studies identified Plasminogen (PLG) as a direct target of miR-206. To give further insights into the participation of the miR-206-PLG network in prostate carcinogenesis in the progeny submitted to maternal LPD. RT-qPCR analysis revealed deregulation of the miR-206-PLG network in the VP of older rats that developed prostate carcinoma in situ. Furthermore, mimic studies revealed a negative correlation between miR-206 and estrogen receptor α (ESR1) expression in PNT2 cells. Together, we demonstrate that early life estrogenization associated with deregulation of miR-206-networks can contribute to the developmental origins of PCa in maternally malnourished offspring. Understanding the molecular mechanisms by which early life malnutrition affects offspring health can encourage the adoption of a governmental policy for the prevention of non-communicable chronic diseases related to the DOHaD concept.