bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS PENEMPATAN TPS DI KECAMATAN PAMEKASAN BERBASIS SISTEM INFORMASI GEOGRAFIS
Authors: Anwari Anwari , Holifi Holifi , Iswahyudi Ary 
Published: January 2022

Abstrak: Penelitian ini bertujuan untuk menentukan Tempat Pembuangan Sementara (Sampah) yang ada di kecamatan pamekasan. Manfaat pada penelitian ini dapat meningkatkan kesadaran masyarakat tentang pentingnya kebersihan dilingkungan sekitar dan tershindar dari segala penyakit dan dapat dijadikan bahan pertimbangan untuk memberikan pelayanan lebih baik lagi terhadap masyarakat. Khususnya untuk membangun Tempat Pembuangan Sementara (Sampah) yang ada dikecamatan pamekasan. Metode penelitian kualitatif deskriptif ini dengan pengumpulan data, wawancara, observasi dan dokumentasi. Hasil penelitian berupa tempat sampah sementara, pembuangan samentara (sampah) berdasarkan hasil penelitian kriteria penempatan TPS / TPS 3R sudah sesuai dalam pasal 20 permen PU nomer 03/PRT/M/2013, maka di temukan 12 desa untuk penempatan TPS yang ada di kecamatan pamekasan, dengan jumlah tempat sampah 77 TPS. Kata Kunci: Lingkungan; Penentuan; SIG; (Sampah) TPS Abstract: This study aims to determine the Temporary Disposal Place (Garbage) in Pamekasan sub-district. The benefits of this study can increase public awareness about the importance of cleanliness in the surrounding environment and avoid all diseases and can be taken into consideration to provide better service to the community. Especially to build Temporary Disposal Sites (Garbage) in the Pamekasan sub-district. This descriptive qualitative research method uses data, observation, and documentation. The results of the study were temporary trash cans, waste disposal based on the results of the research, the criteria for placing TPS / TPS 3R were in accordance with article 20 of the PU Candy number 03 / PRT / M / 2013, so 12 villages were found to place TPS in Pamekasan sub-district , with the TOTAL 77 TPS trash cans. Keywords: determination; environment; of GIS; TPS (waste)
SPIN-CROSSOVER IRON(II) COORDINATION COM­POUNDS: FABRICATION OF FUNCTIONAL MATERIALS AND THEIR INTEGRATION INTO MICRO- AND NANOCONSTRUCTIONS
Authors: Hiiuk Volodymyr , Suleimanov Iurii , Fritsky Igor 
Published: January 2022

Development of micro- and nanosized spin-crossover (SCO) materials has become an important research direction within the past decade. Such an interest is associated with high perceptive of practical application of these materials in nanoelectronic devices. Therefore, researches working in the field of SCO put considerable efforts to obtain SCO complexes in various functional forms, such as nanoparticles, thin films, etc. Fabrication of these materials is realized through different chemical and/or lithographical approaches, which allow to adjust size, shape and even organization of nanoobjects.
In this review theoretical background of SCO phenomenon is described, additionally different classes of coordination compounds exhibiting spin crossover are covered. It is demonstrated that electric field, temperature and light irradiation can be effectively used for switching and control of spin state in nanosized SCO systems. Cooperative SCO with transition close to room temperature, wide hysteresis loop and distinct thermochromic effect is most often observed for Fe(II) coordination complexes. Therefore, Fe(II) SCO compounds form one of the most perspective classes of compounds for obtaining functional materials. It is shown that integration of Fe(II) compounds into micro- and nanohybrid devi­ces allows to combine unique functional pro­perties in one material due to synergy between SCO and physical properties (luminescent, electrical, etc.) of the other component. As a result, SCO compounds are interesting not only from the fundamental point of view, but also from practical, thanks to the possibility of integration of SCO Fe(II) complexes as active materials in devices of different configurations.
It is expected that obtaining of new Fe(II) coordination polymers with unique SCO cha­racteristics will favor the development of new functional materials and devices on their basis in the nearest future.
EVALUASI KELEMBAGAAN PERANGKAT DAERAH KABUPATEN SUMEDANG
Authors: Sinaga Jona Bungaran Basuki 
Published: January 2022

This study aims to analyze the condition of the existing regional equipment of the Sumedang Regency government. The population of this evaluation activity is all regional apparatus organizations in Sumedang Regency. Respondents in this evaluation are the Team assigned by each government agency in accordance with the level of the organization. The evaluation results show that most organizations are in the composite rating category P4. That is, in terms of structure and process, the organization is considered to be classified as effective, able to accommodate the organization’s internal needs and be able to adapt to the dynamics of changes in the organization’s external environment. However, the structure and process of the organization still has several minor weaknesses that can be addressed immediately if improvements are made through routine actions that are marginal. The SKPD in Sumedang District has met the organizational standardsset by the central government, although in some aspects such as the use of information technology and also the openness of data access in each organization has not been implemented to the full.
Keywords: Institutional Evaluation; Organizational structure; Organizational Process
SYSTEMATIC LITERATURE REVIEWS: SISTEM MERIT DALAM MANAJEMEN SUMBER DAYA MANUSIA SEKTOR PUBLIK
Authors: Raharjanto Tri 
Published: January 2022

This study aims to answer conceptual and practical questions about how the concept of merit systems in human resource management, and how to design and implement merit systems abroad. The method applied is Systematic Literature Reviews, which is a literature review method that identifies, evaluates, and interprets all findings on a research topic to answer previously determined research questions. It can be concluded that the concept of merit system in human resource management is a system that places employee competency and performance as the main considerations in selection and promotion. Until now, there is no single design of a merit system that is universal, because each country will make adjustments to their respective legal, social andcultural systems. Furthermore, as a relatively new system in Indonesia, the initial dynamics of the implementation of the merit system were still tinged with various technical and political problems at the regional level.
Keywords: Human Resource Management; Merit System; Meritocracy
EDUKASI BENCANA KEKERINGAN DAN KESIAPSIAGAAN WARGA MASYARAKAT DALAM MENANGGULANGI BENCANA KEKERINGAN DI KABUPATEN LOMBOK TENGAH PROVINSI NUSA TENGGARA BARAT
Authors: Surya Ida Surya , Suwetha I Gusti Ngurah 
Published: January 2022

Geologically, Indonesia is located at the confluence of three of the world's main plates, namely the Indo-Australian Plate, the Eurasian Plate, and the Pacific Plate, which often cause disasters, for example drought. Central Lombok Regency is one of the regencies in West Nusa Tenggara, with these two seasons, most often hit by drought disasters, considering that the rainfall in Central Lombok is very small. So that disaster education and preparedness are needed for residents. This article uses qualitative research methods. The results of the study show that climate field schools have an important role in disaster education. Climate field school is a form of education for farmers that is very useful especially in understanding the weather and climate combined with new agricultural techniques that will allow farmers to plant different crops at different times of the year. Meanwhile, for preparedness, it is carried out through several programs in the form of urging and asking farmers to be disciplined in carrying out cropping patterns according to the zoning in which they are located (rice-padi-palawija or padi-palawija-palawija), mapping of land related to cropping patterns, planting rice parity that requires little water, namely the Situpagendit variety, and urges farmers to insure their rice plants, which is Rp. 36.000/ Ha for one planting season at PT. JASINDI.

Keywords: Indonesia's geological location, disaster, disaster education.
UPAYA PEMERINTAH DAERAH DALAM PENANGANAN PANDEMI COVID-19 DI KABUPATEN GARUT
Authors: Kurniawan Rana Putri , Giffary Muhammad Alvin , Marbun Wendy 
Published: January 2022

The pandemic that is endemic throughout the world is making every country work hard to eradicate it. has been declared by the World Health Organization (WHO) as a Global Public Health Emergency which is known to spread to all corners of the world very quickly. Coronavirus is a new virus that causes illness ranging from mild to severe symptoms. There are at least two types of corona viruses that cause serious illness, namely Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS). Coronavirus disease 2019 (COVID-19) is a new disease that has never been identified in humans. The virus that causes is called SarsCoV2. COVID-19 is a new disease and there is very little research on it. Evidence-based information is required for the care, treatment and other information related to this disease. The Indonesian government later declared the Corona problem as an unnatural or non-natural national disaster. The President of the Republic of Indonesia, regional governments and their staff work together in various efforts to prevent the spread of the virus in the community. From ministerial level to province, district or city
Keywords: Pandemic, Local Government, Efforts
POTENSI GANGGUAN KETENTERAMAN DAN KETERTIBAN UMUM DI PEMILIHAN KEPALA DESA DAN PEMILIHAN KEPALA DAERAH (PERNAK PERNIK PEMILIHAN LANGSUNG)
Authors: Suhendi Dedy 
Published: January 2022

Village head elections (pilkades) are political activities / events that show how the process (party) of democracy is at the village level. Pilkades is not merely a transfer of leadership for the sustainability of government and development in the village, or how a power struggle with a campaign strategy is carried out in order to get sympathy and support from the village community, but more than that it concerns prestige / dignity and honor so that it often creates tough competition and conflict. Since the enactment of Law no. 23 of 2004 and now Law no. 32 of 2014 concerning Regional Government, regional heads are directly elected by the people.
This study aims to explain the possible potential for disturbances of peace and public order that can occur during the pre-post-regional head elections such as village head elections which result in disturbances of peace and public order, then try to analyze and study and anticipate as an effort to minimize possible disturbances.
The method used in this research is descriptive research method by emphasizing the researcher's efforts to describe the phenomenon based on the experiences of research participants while on duty in the region and supplemented with the results of observations.
The final results of this study are expected to be able to provide recommendations and solutions to a more appropriate “pilkada” model. The conclusion of this research is in order to enforce peace and public order in the regions by preventing disturbances of peace and order from pre to post Pilkada.
IMPLEMENTASI PERATURAN DAERAH NOMOR 4 TAHUN 2018 TENTANG KAWASAN TAN PAROKOK DI SEKRETARIAT PEMERINTAHAN DAERAH KABUPATEN SELUMA PROVINSI BENGKULU
Authors: Utama Toby Yasa , Assuncao Simao De , Eviany Eva 
Published: January 2022

Masalah yang dihadapi oleh pemerintah Kabupaten Seluma salah satunya mengenai penerapan kebijakan kawasan tanpa rokok sejauh ini pelaksanaannya belum berjalan secara optimal demi terwujudnya lingkungan kerja yang sehat tanpa asap rokok. Tujuan dari penelitian ini adalah: 1) untuk mengetahui dan menjelaskan implementasi kebijakan Peraturan Daerah Nomor 4 Tahun 2018 tentang Kawasan Tanpa Rokok di Sekretariat Pemerintahan Daerah Kabupaten Seluma; 2) untuk menjelaskan dan menganalisis mengenai faktor-faktor penghambat dalam pelaksanaan implementasi kebijakan kawasan tanpa rokok; 3) untuk menjelaskan dan menganalisis upaya-upaya pemerintah daerah dalam menegakkan peraturan Daerah Nomor 4 Tahun 2018 tentang Kawasan Tanpa Rokok di Sekretariat Pemerintahan Daerah Kabupaten Seluma. Metode penelitian yang dilakukan bersifat deskriptif kualitatif. Hasil dari implementasi kebijakan kawasan tanpa rokok yang pertama, belum terlaksana secara optimal disebabkan permasalahan mendasar yang menjadi penghambat dalam pelaksanaannya. Kedua, faktor penghambat dalam pelaksanaannya terdiri dari faktor internal dan eksternal. Ketiga, upaya yang harus dilakukan pemerintah daerah dalam implementasi kebijakan yaitu pihak penegak hukum (Satuan polisi pamong praja) harus tegas dalam pelaksanaan turun ke lapangan, menyediakan fasilitas berupa Smoking Area, menguatkan dan menegaskan sanksi.
Kata Kunci: Implementasi, Kawasan Tanpa Rokok, Aparatur Sipil Negara, Kabupaten Seluma
PEMBINAAN PENERAPAN PROTOKOL KESEHATAN KEPADA MASYARAKAT DI KECAMATAN PURWAKARTA KABUPATEN PURWAKARTA PROVINSI JAWA BARAT
Authors: Hariyanto Restu Ragyl , Satyanagara Ajisaka Bagas , Cahyani Alfonsa Agustina Eka 
Published: January 2022

Penulisan artikel ini bertujuan untuk mengetahui apa saja kendala atau hambatan yang terjadi dalam pelaksanaan pembinaan penerapan protokol kesehatan kepada masyarakat di Kecamatan Purwakarta Kabupaten Purwakarta. Metode penelitian yang dilakukan melalui metode deskriptif dengan pendekatan kualitatif. Informan penelitian hanya satu orang yaitu Kepala Bidang Perlindungan Masyarakat dan masyarakat sekitar. Teknik pengumpulan data yang digunakan adalah wawancara dan studi dokumentasi. Hasil penelitian menunjukan bahwa pelaksanaan pembinaan penerapan protokol kesehatan kepada masyarakat di Kecamatan Purwakarta pada pelaksanaanya masih belum optimal. Terdapat beberapa kendala atau hambatan dalam pelaksanaan yaitu seperti terbatasnya personil dari Satpol PP yang bertugas di Kecamatan Purwakarta dan masih ada masyarakat yang belum sadar akan pentingnya protokol kesehatan untuk mencegah penularan Covid-19. Hal ini mengakibatkan jumlah kasus Covid-19 terus meningkat.
Kata Kunci : Pembinaan, Protokol Kesehatan, Satpol PP
MEMELIHARA KETENTERAMAN DAN KETERTIBAN UMUM MELALUI LITERASI MEDIA DI KELURAHAN KARIANGAAU KECAMATAN BALIKPAPAN BARAT KOTA BALIKPAPAN
Authors: Rahmadanita Annisa , Nurrahman Agung 
Published: January 2022

Informasi Hoax yang dipercayai oleh sebagian masyarakat dapat mengganggu ketenteraman dan ketertiban umum di wilayah Kelurahan Kariangau. Adapun tujuan penelitian ini adalah untuk memperoleh gambaran umum dan mendeskripsikan urgensi dari literasi media dalam memelihara ketenteraman dan ketertiban umum di Kelurahan Kariangau. Penelitian ini merupakan penelitian deskriptif kualitatif. Temuan penelitian menunjukkan bahwa secara teknis, masyarakat Kariangau mampu menggunakan media dengan cukup baik. Namun sebagian masyarakat Kariangau belum mampu memahami apakah informasi tersebut adalah informasi Hoax atau tidak, terutama saat informasi tersebut diperoleh melalui Whatsapp Gorup keluarga. Sehingga sebagian masyarakat mempercayai semua informasi yang diperoleh dari media tersebut. Di sisi lain, sebagian besar masyarakat Kariangau telah berpartisipasi dalam menindaklanjuti informasi yang diperoleh dari suatu media khususnya media sosial, dengan mencari kebenaran informasinya terlebih dahulu atau melakukan penyaringan informasi sebelum informasi tersebut disebarkan kepada orang lain. Kesimpulan penelitian ini adalah bahwa sejauh ini literasi media secara pribadi telah dilakukan oleh masyarakat Kariangau dengan cukup baik, namun pemerintah Kelurahan Kariangau belum memiliki program literasi media secara khusus untuk masyarakat. Sehingga peneliti merekomendasikan bahwa dilihat dari urgensinya, maka program literasi media perlu disusun dan dilaksanakan secara terencana, sistematis dan berkelanjutan oleh Pemerintah Kelurahan Kariangau dan juga dapat membentuk Kelompok Informasi Masyarakat untuk melakukan edukasi kepada masyarakat.

Kata Kunci: Literasi Media, Ketenteraman dan Ketertiban Umm, Kelurahan
Aplicación de anticuerpos monoclonales en oncología
Authors: Enriquez-Vera Daniel 
Published: January 2022

Los anticuerpos monoclonales representan una pieza fundamental en el arsenal terapéutico en oncología. Estos compuestos biológicos de alta complejidad han logrado mejorar la supervivencia de los pacientes con cáncer. Entre los clásicos se encuentran: rituximab, bevacizumab, cetuximab, trastuzumab utilizados a diario en nuestro medio. En la última década, la inmunoterapia se ha posicionado como una terapia eficaz para neoplásias de pronóstico adverso como el melanoma, cáncer de pulmón y renal. En el futuro próximo, los nuevos conjugados de anticuerpos y la terapia con células T quiméricas se presentarán como paradigmas de terapias promisorias en el manejo del cáncer.
A Novel Nomogram for Predicting the Risk of Premature Delivery Based on the Thyroid Function in Pregnant Women
Authors: Meng Yu , Lin Jing , Fan Jianxia 
Published: January 2022

BackgroundMaternal thyroid dysfunction and autoantibodies were associated with preterm delivery. However, recommendations for cutoff values of thyroperoxidase antibody (TPOAb) positivity and thyroid-stimulating homone (TSH) associated with premature delivery are lacking.ObjectiveTo identify the pregnancy-specific cutoff values for TPOAb positivity and TSH associated with preterm delivery. To develop a nomogram for the risk prediction of premature delivery based on maternal thyroid function in singleton pregnant women without pre-pregnancy complications.MethodsThis study included data from the International Peace Maternity and Child Care Health Hospital (IPMCH) in Shanghai, China, between January 2013 and December 2016. Added data between September 2019 and November 2019 as the test cohort. Youden’s index calculated the pregnancy-specific cutoff values for TPOAb positivity and TSH concentration. Univariate and multivariable logistic regression analysis were used to screen the risk factors of premature delivery. The nomogram was developed according to the regression coefficient of relevant variables. Discrimination and calibration of the model were assessed using the C-index, Hosmer-Lemeshow test, calibration curve and decision curve analysis.Results45,467 pregnant women were divided into the training and validation cohorts according to the ratio of 7: 3. The testing cohort included 727 participants. The pregnancy-specific cutoff values associated with the risk of premature delivery during the first trimester were 5.14 IU/mL for TPOAb positivity and 1.33 mU/L for TSH concentration. Multivariable logistic regression analysis showed that maternal age, history of premature delivery, elevated TSH concentration and TPOAb positivity in the early pregnancy, preeclampsia and gestational diabetes mellitus were risk factors of premature delivery. The C-index was 0.62 of the nomogram. Hosmer-Lemeshow test showed that the Chi-square value was 2.64 (P = 0.955 &gt; 0.05). Decision curve analysis showed a positive net benefit. The calibration curves of three cohorts were shown to be in good agreement.ConclusionsWe identified the pregnancy-specific cutoff values for TPOAb positivity and TSH concentration associated with preterm delivery in singleton pregnant women without pre-pregnancy complications. We developed a nomogram to predict the occurrence of premature delivery based on thyroid function and other risk factors as a clinical decision-making tool.
Promising Immunotherapy in Metastatic Testicular Sex Cord Stromal Tumours After First-Line Chemotherapy
Authors: Shang Bingqing , Cao Chuanzhen , Jiang Weixing , Shi Hongzhe , Bi Xingang , Cui Chengxu , Shou Jianzhong , Zheng Shan , Zhang Jin , Zhou Aiping , Li Changling , Ma Jianhui 
Published: January 2022

BackgroundTesticular sex cord stromal tumours (TSCSTs) are rare, with few studies focusing on the metastatic TSCST prognosis. The value of treatments, including radical orchiectomy (RO) and retroperitoneal lymph node dissection (RPLND), in preventing metastasis is controversial. Additionally, metastatic TSCSTs are resistant to chemotherapy. We aimed to assess the effectiveness and safety of immunotherapy in metastatic TSCSTs after first-line chemotherapy.MethodsWe retrospectively screened patients with testicular tumours undergoing testis surgery between January 2005 and January 2019. Patients with TSCSTs who had undergone testis-sparing surgery (TSS) or RO were identified. The malignant type was defined as metastasis confirmed by pathology. Treatment responses, progression-free survival (PFS), overall survival (OS) and safety were analysed.ResultsAmong the 494 testicular tumour patients who received TSS or RO, 11 (2.2%) patients with histologically proven TSCSTs were identified. At the last follow-up, 7 patients survived without tumours, and 4 patients developed metastasis and received first-line cisplatin-based chemotherapy, with 1 of them achieving an objective response. Their PFS times were 1.5, 2.2, 9.0, and 17.0 months, respectively. Two patients received immune checkpoint inhibitors (ICIs) after developing chemotherapy resistance and achieved a partial response up to the last follow-up; one of them experienced Grade 1 adverse events, and the other experienced Grade 2 adverse events during immunotherapy. The median OS time of the 4 patients with metastatic TSCSTs was 32 months.ConclusionsTSCSTs are rare, and most are benign with a good prognosis. ICIs represent a promising option for improving clinical outcomes in metastatic TSCSTs.
Association of Circulating Magnesium Levels in Patients With Alzheimer's Disease From 1991 to 2021: A Systematic Review and Meta-Analysis
Authors: Du Ke , Zheng Xi , Ma Zi-Tai , Lv Jun-Ya , Jiang Wen-Juan , Liu Ming-Yan 
Published: January 2022

Alzheimer's disease (AD) remains a medical and social challenge worldwide. Magnesium (Mg) is one of the most frequently evaluated essential minerals with diverse biological functions in human body. However, the association between circulating Mg levels and AD remains controversial. We conducted a meta-analysis of 21 studies published between 1991 and 2021 to determine whether the Mg levels in the blood and cerebrospinal fluid (CSF) are abnormal in AD. Literatures were searched in PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and Wanfang Data without language limitations. A pooled subject sample including 1,112 AD patients and 1,001 healthy controls (HCs) was available to assess Mg levels in serum and plasma; 284 AD patients and 117 HCs were included for Mg levels in CSF. It was found that serum and plasma levels of Mg were significantly reduced in AD patients compared with HCs (standardized mean difference [SMD] = −0.89; 95% confidence interval [CI] [−1.36, −0.43];P= 0.000). There was statistically non-significant for Mg level in CSF between AD and HCs, whereas a decreased tendency were detected (SMD = −0.16; 95% CI [−0.50, 0.18];P= 0.364). .In addition, when we analyzed the Mg levels of serum, plasma and CSF together, the circulating Mg levels in AD patients was significantly lower (SMD = −0.74, 95% CI [−1.13; −0.35];P= 0.000). These results indicate that Mg deficiency may be a risk factor of AD and Mg supplementation may be a potentially valuable adjunctive treatment for AD.Systematic Review Registration:www.crd.york.ac.uk/PROSPERO/, registration number CRD42021254557.