bluuebunny/crossref_metadata_2025_split huggingface dataset:
Construction of H6PW9V3O40@rht‐MOF‐1 for deep oxidative desulfurization of fuel oil
Authors: Bai Yiyang , Xin Yuxiang , Liu Jiabin , Ma Liqiang , Li Guangming 
Published: February 2022

AbstractDeep desulfurization is impending for environmental conservation by way of reducing supplied emissions from fuel oil. Developing new and effective catalysts on deep desulfurization is still a great changeling. In this piece of work, a series of three H3+nPW(12‐n)VnO40@rht‐MOF‐1 have been synthesized by one‐pot self‐assembly hydrothermal reaction of CuCl2·2H2O and 5‐tetrazolyl isophthalic acid (H3TZI) with three H3+nPW(12‐n)VnO40 (polyoxometalates [POMs]), respectively. X‐ray crystallographic analysis reveals that the POMs have been successfully encapsulated in the cages of rht‐MOF‐1. The affording complex 3, as heterogeneous catalyst, is able to effectively catalyze the extraction catalytic oxidation desulfurization system (ECODS) of model oil and real fuel oil under mild reaction conditions. The remarkable encapsulation of POMs in rht‐MOF‐1 resulted in the heterogeneous catalysis, enabling it to be recycled in the system. The reaction kinetics has been investigated, and the redial reaction mechanism has been verified by electron paramagnetic resonance (EPR) analysis and radical quenching experiments. This approach provides an easy and effective route on developing heterogeneous catalysts that could be applied in the deep ECODS of fuel oil.
Study on two‐stage stretching strategy for microstructure improvement of polytetrafluoroethylene hollow fiber membrane
Authors: Jia Jingxuan , Zhou Meiqing , Liu Dandan , Li Meng , Kang Guodong , Cao Yiming 
Published: February 2022

AbstractPolytetrafluoroethylene (PTFE) has excellent chemical resistance, thermal stability as well as hydrophobicity, and is regarded as a good material for membrane fabrication. PTFE hollow fiber membrane is commonly prepared by the paste extrusion–stretching–sintering process, where the stretching temperature is usually fixed in existing reports. In this paper, a new two‐stage stretching method (first at 50°C and then at 200°C) was proposed to optimize the microstructure of PTFE hollow fiber membranes. Meanwhile, the stretching experiments at low‐temperature (50°C) and high‐temperature (200°C) were also conducted for comparison. The chemical composition, surface morphology, surface porosity, overall porosity, maximum pore size, water contact angle, and mechanical property were discussed. Moreover, the ethanol permeation flux and bovine serum albumin (BSA) rejection of PTFE hollow fiber membranes prepared from different stretching manners were tested. The results showed that with the increase of stretching ratio, the porosity, and pore size gradually increased for all three membranes. However, for a specific stretching ratio, the membrane fabricated by two‐stage stretching process exhibited better comprehensive properties in terms of porosity and pore size, that is, higher porosity than the 50°C method and smaller pore size than the 200°C method. As stretching ratio was 2.0, the ethanol permeation flux and BSA rejection was 2467 L/m2 h and 95%, respectively. Overall, the PTFE hollow fiber prepared from “two‐stage” stretching exhibited comparable BSA rejection (both around 95%) and much higher permeation flux (increased by 43.1%) compared to the sample prepared by low‐temperature stretching at 50°C, and meanwhile, comparable permeation flux (decreased by 10.8%) and higher BSA rejection (95% against 81%) compared to the sample prepared by high‐temperature stretching at 200°C. The proposed method provided a good reference for the microstructure improvement of PTFE hollow fiber membrane fabricated by paste extrusion–stretching–sintering technology.
Visual working memory performance is intact across development in autism spectrum disorder
Authors: Lynn Andrew , Luna Beatriz , O'Hearn Kirsten 
Published: February 2022

AbstractAutism spectrum disorder (ASD) is associated with atypical visual processing and deficits in working memory (WM). Visual WM performance typically improves between childhood and adulthood, but such improvement may be atypical in ASD. To better understand how visual WM develops, we used a well‐established change detection task across multiple visual features. We examined visual WM for color, shape, and pattern in children, adolescents, and adults with and without ASD. VWM capacity and performance for all visual features improved across age similarly for both the TD and ASD groups. While performance was better on set size 4 trials than set size 8 trials for color, shape, and no change trials, such an effect was not evident for pattern change trials. Overall, the present findings suggest that VWM for different visual features may be intact across development in ASD. The ability to hold multiple objects in mind (WM) improves across typical development, but it remains unclear whether such improvement occurs in ASD. We found that developmental improvements in WM for different types of object details (e.g., color, shape, and pattern) is generally similar for both ASD and typical development.Lay SummaryThe ability to hold multiple objects in mind (working memory [WM]) improves across typical development, but it remains unclear whether such improvement occurs in autism spectrum disorder (ASD). We found that developmental improvements in WM for different types of object details (e.g., color, shape, pattern) is generally similar for both ASD and typical development.
Engineered yeast for efficient de novo synthesis of 7‐dehydrocholesterol
Authors: Qu Lisha , Xiu Xiang , Sun Guoyun , Zhang Chenyang , Yang Haiquan , Liu Yanfeng , Li Jianghua , Du Guocheng , Lv Xueqin , Liu Long 
Published: February 2022

AbstractThe synthesis of vitamin D3 precursor 7‐dehydrocholesterol (7‐DHC) by microbial fermentation has much attracted attention owing to its advantages of environmental protection. In this study, Saccharomyces cerevisiae was engineered for a de novo biosynthesis of 7‐DHC. First, seven essential genes (six endogenous genes and one heterologous gene) were overexpressed, and the ROX1 gene (heme‐dependent repressor of hypoxic genes) was knocked out. The resulting strain produced 82.6 mg/L 7‐DHC from glucose. Then, we predicted five gene knockout targets for 7‐DHC overproduction by the reconstruction of genome‐scale metabolic model. GDH1 gene knockout increased the 7‐DHC titer from 82.6 to 101.5 mg/L, and the specific growth rate of the ΔGDH1 mutant was also increased by 28%. Next, Ty1 transposon in S. cerevisiae was applied to increase the copies of the ERG1 gene and DHCR24 gene, resulting in a 120% increase in 7‐DHC titer to 223.3 mg/L. Besides, to optimize the metabolic flux distribution, Clustered Regularly Interspaced Short Palindromic Repeats interference (CRISPRi) system was used to dynamically inhibit the competitive pathway, and the best binding site of ERG6 (delta (24)‐sterol C‐methyltransferase) promoter was screened out. The OD600 value of ERG6 regulated cells increased by 43% than knocking out ERG6 directly, and 7‐DHC titer increased to 365.5 mg/L in a shake flask. Finally, the 7‐DHC titer reached 1328 mg/L in 3‐L bioreactor and the specific titer of 7‐DHC reached up to 114.7 mg/g dry cell weight). Overall, this study constructed a yeast chassis for the highly efficient production of 7‐DHC by systems metabolic engineering.
Referral process to further evaluate poor sleep in breast cancer survivors
Authors: Otte Julie L. , Chernyak Yelena , Johns Shelley A. , Jackson Lea' , Ludwig Kandice K. , Dodson Jill , Manchanda Shalini , Bufink Elizabeth , Draucker Claire 
Published: February 2022

AbstractObjectiveBreast cancer survivors (BCS) are twice as likely to report symptoms of poor sleep as those without cancer. However, sleep disorders are under‐assessed and under‐treated among BCS. The purpose of this study was to determine the portion of BCS who completed referral visits to a sleep specialist and identify the acceptability, facilitators, and barriers to the screening and referral process.MethodsBCS, who reported having sleep problems, completed questionnaires to screen for symptoms suggestive of sleep disorders. Those with symptoms suggestive of sleep apnea, movement disorders, narcolepsy, insomnia syndrome, or circadian disorders, they were referred to a sleep medicine physician or behavioral sleep medicine psychologist. Two months after the referral, participants were interviewed about their perceptions of the acceptability, barriers, and facilitators to sleep screenings and referrals.ResultsOf 34 BCS assessed for eligibility, 29 were eligible and had sleep problems. Only eight of 29 participants (27.6%) completed the sleep referral process. Most thought the screening and referral process was acceptable. However, BCS identified barriers to completing the referral visit, including time, not seeing the need for treatment, insurance/sick leave concerns, and distance/transportation.ConclusionAdequate evaluation and treatment of sleep disorders in BCS are rare. Creative solutions to address barriers to timely sleep referrals are needed to reduce long‐term negative consequences of inadequate sleep.
Impacts of weathering/preharvest sprouting in the field on the milling and flour quality of soft wheats, and resulting baking performance for soft wheat‐based baked products
Authors: Kweon Meera , Slade Louise , Levine Harry 
Published: February 2022

AbstractBackground and ObjectivesPreharvest sprouting (PHSing) of wheat induces more heterogeneous germination in the field than in a controlled laboratory setting, but the former phenomenon has not been studied extensively to date. In the present study, the impacts of field‐weathering (FWing)/PHSing in soft wheats on resulting flour quality and baking performance, for soft wheat‐based baked products, were explored for twelve soft wheat cultivars.FindingsFWing/PHSing in soft wheats significantly affected test weight, break flour yield, falling number, α‐amylase activity, and solvent retention capacity. Starch‐pasting profiles for flour samples with different wheat harvest times appeared to potentially show four groups of behavior. However, the impacts of FWing/PHSing in the wheats studied were negligible on the resulting baking performance of pancakes, cookies, and crackers, but were dramatic for Japanese‐type sponge cake.ConclusionsEffects of FWing/PHSing in soft wheats on resulting wheat and flour quality, milling performance, and baking performance were confirmed. The set of tested flours in the study, milled from field‐weathered (FWed)/PH sprouted (Sed) soft wheat grains, exhibited four groups of behavior in starch‐pasting profiles, which varied significantly with wheat genotype.Significance and NoveltyA comprehensive study of FWed/PHSed soft wheats, conducted to cover different wheat genotypes and different types of baked products, is reported here for the first time.
Novel PKLR missense mutation (A300P) causing pyruvate kinase deficiency in an Omani Kindred—PK deficiency masquerading as congenital dyserythropoietic anemia
Authors: Fawaz Naglaa , Beshlawi Ismail , Alqasim Alauldeen , Zachariah Mathew , Russo Roberta , Andolfo Immacolata , Gambale Antonella , Pathare Anil , Iolascon Achille 
Published: February 2022

AbstractWe report herein a child with transfusion‐dependent chronic anemia, the cause of which was difficult to establish because of his transfusion dependency. The clinical and laboratory features suggested a chronic nonspherocytic hemolytic anemia (CNSHA) with bone marrow features suggestive of congenital dyserythropoietic anemia (CDA). DNA studies, however, revealed the underlying condition to be due to a novel mutation in the PKLR gene responsible for pyruvate kinase deficiency (PKD). Molecular investigations by a targeted next‐generation sequencing (t‐NGS) using a custom panel of 71 genes involved in the red blood cell (RBC) disorders revealed that the patient was homozygous for a novel missense mutation c.898G>C, p.Ala300Pro, whereas both his parents were heterozygous for the same mutation.
Palladium‐Catalyzed Cascade Deboronation/Regioselective B−P Coupling of closo‐Carboranes
Authors: Yang Ziyi , Sun Chaofan , Wei Xing , Lu Jian , Lu Ju‐You 
Published: February 2022

AbstractA cascade deboronation/regioselective B−P coupling of closo‐carboranes is disclosed using a combination of palladium catalysts and nitrogen or phosphine‐containing directing groups. Unsymmetric C‐substituted closo‐carboranes, including C‐monosubstituted and unsymmetric 1,2‐disubstituted closo‐carboranes, are tolerated. Select closo‐carboranes bearing other directing groups, such as benzoxazole, and diphenylphosphine, are compatible substrates for this reaction. Phosphine and arsenic can be utilized as effective coupling partners. Furthermore, a catalytic amount of palladium salt mediates the regioselective B−H activation process. Readily available closo‐carboranes as the starting materials for direct one‐pot synthesis of functionalized nido‐carboranes and the in‐situ formation of nido‐carborane intermediates without purification are important features in terms of practical applications.
Model‐Based Analysis to Increase the Substrate Efficiency of a Biogas Plant
Authors: Seick Ingolf , Vergara-Araya Mónica , Wiese Jürgen 
Published: February 2022

AbstractA biogas plant is fed with agricultural substrates at an average organic loading rate of 6 kgVS per m3 fermenter volume per day and substrates with relatively high nitrogen content. This situation results in a below‐average methane yield, so the aim is to increase the substrate efficiency. An analysis of the actual condition of the plant was performed and compared with reference values. A dynamic simulation model of the biogas plant was created and adjusted with data over an operating year. The model adjustment provided a good approximation of the simulation results to the key operating variables and thus allows the evaluation of different operating variations. The effect of various measures was analyzed by simulation and it showed a potential increase in substrate efficiency of up to 15 %.
Associations among clinical variables and anger differ by early life adversity among post‐9/11 veterans
Authors: Etchin Anna G. , Corbo Vincent , Brown Emma , Fortier Catherine B. , Fonda Jennifer R. , Milberg William P. , Currao Alyssa , McGlinchey Regina E. 
Published: February 2022

AbstractMaladaptive anger and aggression are common in US military veterans and increase risk for impaired social relationships and functioning, justice‐involvement and violence. Early life (before age 18) adversity predisposes veterans to later life psychopathology, though the link to increased later life anger is unclear. We analysed cross‐sectional data of 158 post‐9/11 veterans from the Translational Research Center for Traumatic Brain Injury and Stress Disorders study with and without a history of early life adversity (ns = 109 and 49, respectively). We explored the relationship among major clinical variables and current veteran anger (Dimensions of Anger Reactions) and whether the associations with these variables differed among participants with and without a history of retrospective self‐reported early life adversity (Childhood Trauma Questionnaire). In the overall sample, posttraumatic stress disorder (PTSD) and depression severities had the strongest associations with current veteran anger (βs = 0.261 and 0.263; p‐values = 0.0022 and 0.0103, respectively). In the subsample without early life adversity, only PTSD severity was significantly associated with anger (β = 0.577, p = 0.0004). In the early life adversity subsample, this strong association weakened and was no longer significant (β = 0.168, p = 0.1007); instead, anxiety and depression severities showed moderate associations with anger (βs = 0.243 and 0.287, p‐values = 0.0274 and 0.0130, respectively). Findings suggest that clinicians should screen veterans with history of early life adversity for depression and anxiety when anger is present.
Insights into the Electrochemical Reduction of 5‐Hydroxymethylfurfural at High Current Densities
Authors: de Luna Giancosimo Sanghez , Sacco Adriano , Hernandez Simelys , Ospitali Francesca , Albonetti Stefania , Fornasari Giuseppe , Benito Patricia 
Published: February 2022

AbstractThe electrocatalytic reduction of 5‐hydroxymethylfurfural (HMF) is highly selective to 2,5‐bishydroxymethylfuran (BHMF) at pH=9.2, diluted HMF solutions, and low current densities. In this work, the electrochemical reduction of 0.05 m HMF solutions was investigated in the 5–50 mA cm−2 current density range over an AgCu foam electrocatalyst. The selectivity towards the formation of BHMF or the dimerization depended on the current density, likely due to differences in the electrode potential, and on the reaction time. Operating at current densities of 40–50 mA cm−2 allowed to find a trade‐off between HMF and H2O activation, achieving 85 % BHMF selectivity and fostering the productivity (0.567 mmol cm−2 h−1), though co‐producing H2. The electrochemical characterization by Tafel slopes and electrochemical impedance spectroscopy indicated that the HMF reduction was kinetically favored in comparison to the hydrogen evolution reaction and that the process was limited by charge transfer.
Blind interference alignment: A comprehensive survey
Authors: U Vivek Menon , Selvaprabhu Poongundran 
Published: February 2022

SummaryInterference is a crucial impairment for trustworthy wireless communication. To overcome this interference problem, many interference management strategies have been established. Interference alignment (IA) is one such significant interference management approach that handles the positioning of signals so that they form an overlapping shadow at the unintended receivers; the desired interference‐free signals remain separable at the intended receivers. However, the need for global channel state information at the transmitter (CSIT) acts as a practical limitation for IA in the real‐world wireless communication system. IA can mitigate this limitation associated with channel state information with no CSIT, also termed as blind IA (BIA). Therefore, BIA is an interference management strategy that utilizes the concept of IA with no knowledge of CSIT. Therefore, based on the plethora of prevailing significant works, the objective of our paper is to provide a comprehensive survey to draw a picture of BIA in terms of network topologies, applications in different networks, trending research areas, degrees of freedom (DoF), open‐research problems, and future research directions.
Community homeostasis of coastal microbial mats from the Camargue during winter (cold) and summer (hot) seasons
Authors: Berlanga Mercedes , Palau Montserrat , Guerrero Ricardo 
Published: February 2022

AbstractMicrobial mats are complex layered biofilms under the effect of continuous daily and seasonal fluctuations in abiotic factors such as nutrients, pH, light, temperature, and salinity. In this study, community variability of microbial mats from the Camargue wetlands (Rhone Delta, southern France) was determined in winter and summer over 2 years, analyzing thin vertical layers at three different depths (0–2, 2–4, and 4–6 mm). Amplicons of the V1–V2 region of the 16S rRNA gene were sequenced to assess changes in the bacterial diversity of the mats. Functionality was inferred according to PICRUSt bioinformatics analysis. The microbial composition of the three layers included more than 30 phyla of bacteria, the major phyla being Proteobacteria, Bacteroidetes, Cyanobacteria, and Spirochaetes. The microbial composition of the layers differed significantly, especially between layer 1 (0–2 mm) and the other two, regardless of the season. Cyanobacteria and Rhodobacteraceae (Alphaproteobacteria) were more abundant in layer 1. Chromatiaceae (Gammaproteobacteria) and Deltaproteobacteria were detected in layers 2 (2–4 mm) and 3 (4–6 mm). Flavobacteriaceae was the predominant family of the phylum Bacteroidetes, being especially abundant in layer 3. Spirochaetes were distributed in all three layers, but above all in layer 2. Pathways related to energy and carbohydrate metabolism indicated that the community was more active in summer than in winter. Carbon fixation in the mats was predominantly through the Wood–Ljungdahl pathway. Heterotrophic diazotrophs appeared to be responsible for a substantial part of nitrogen input, even more than phototrophic microorganisms. Layers 1 and 2 represented a stressed environment, measured by relative abundances of KEGG Orthologs associated with oxidation, starvation, and osmotic and xenobiotic stress, and suffered unbalanced growth in which there is no increase in cell numbers, but it allows the accumulation of polymers, such as polyhydroxybutyrate. The Camargue mats showed a community homeostasis, its populations adapting to fluctuating conditions while maintaining the characteristic structure of vertically stratified functional groups of microorganisms.
Plant functional traits as measures of ecosystem service provision
Authors: Miedema Brown Liane , Anand Madhur 
Published: February 2022

AbstractDespite the relevance of ecosystem services (ES) to society and modern ecological research, current methods of measurement and mapping remain inconsistent and often lack primary data in estimating and modeling ES. A key player in our understanding of ES and their measurements are plant functional traits—chemical and physical aspects of plants—which are often cited as one of the drivers of ecosystem processes and functions. In order to better quantify the ES–plant functional trait indicators, we outline existing evidence of this relationship and identify gaps between the best predicted ES and the most valued ES. This study offers an up‐to‐date review of plant functional traits' direct or indirect relationships with ecosystem service provision and discusses the quantitative evidence these traits might hold as indicators. With this review, we seek to (1) offer a current summary of the quantitative evidence on ecosystem service–plant functional trait relationships, (2) identify which traits have been used to successfully indicate ecosystem services, and (3) identify research gaps, and ecosystem services or traits that receive little attention or have weak criteria as indicators. In a comprehensive literature review of the 19 services that were searched for, genetic materials, medicine, and cultural services had no relevant plant functional trait indicators, while the remaining 16 services had a range of traits associated with them. We found that functional traits showed varying relationships to ES, with some depending on the ecosystem type they were found in, while others appeared to remain consistent across ecosystems and conditions. This indicates that there could exist a subset of traits that are “universal” indicators across all ecosystem types, while others are ecosystem dependent. Our review suggests the need for more research on less clearly defined ES (such as cultural, educational, and refugium services) both by more careful definitions to make quantitative measures more applicable, and through increased quantitative and qualitative studies to better understand the nature of ES indicators for these services. This summary shows how plant functional traits can quantitatively and reliably predict and provide details on a subset of ES.