bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endothelial function status in hypogonadal men
Authors: Khripun I. A. , Vorobyev S. V. 
Published: January 2022

Background: Type 2 diabetes mellitus (T2DM) and hypogonadism are mutually aggravating diseases associated with the development and progression of cardiovascular pathology. The status of endothelial function in men with T2DM and hypogonadism hasn’t been studied.Aims: To assess the effect of hypogonadism on endothelial function in men with T2DM.Materials and methods: Patients underwent clinical studies, assessment of carbohydrate and lipid metabolism, the content of sex hormones (total testosterone (T), sex hormones binding globulin, free T, luteinizing hormone) and markers of endothelial function (nitric oxide (NO), endothelial nitric oxide synthase type 3 (eNOS3), endothelin, adhesion molecules ICAM-1, VCAM-1, p- and e-selectins, cadherin), ultrasound examinations of endothelium-dependent vasodilation (EDVD) of the brachial artery (BA) and carotid arteries with an assessment of the thickness of intima-media complex (TIM) were performed.Results: The study included 276 men with T2DM (age 54.0[49;60] years), who were divided into 2 groups: 1–124 patients with hypogonadism; 2–152 eugonadal patients. Reduction of the endothelial vasomotor function was detected in 32.4% of patients in the 2st group and in 55.3% of the 1nd group (χ2=6.1; p=0.01), which was associated with a decrease in EDVD by 29.8 % (p<0.001) and an increase in the time of development of maximal BA vasodilation by 30 seconds in patients with hypogonadism (p<0.001). The TIM of the carotid arteries was 10% more in group 1 compared with group 2 (p=0.03). The ­level of NO in the 1st group was reduced by 1.6 times (p=0.001), eNOS3–by 1.5 times (p=0.038) compared with the 2nd group. The concentrations of adhesion molecules were higher in group 1 compared to group 2: VCAM-1 by 32.5% (p<0.001), ICAM-1 by 43.5% (p<0.001), p-selectin–by 19.3% (p=0.004), cadherin–6 times (p<0.001).Conclusion: Hypogonadism in men with T2DM is associated with the development of endothelial dysfunction, which manifests in a weakening of the EDVD and a slowdown in its development, as well as disturbances of the secretory activity of endothelium–a decrease in NO synthesis and activation of the adhesion molecules expression, which can be regarded as an universal pathogenetic mechanism of the development of cardiovascular diseases in combination of T deficiency and T2DM.
Ethnic characteristics of bone remodeling in female patients with type 2 diabetes mellitus
Authors: Bardymova T. P. , Shestakova M. V. , Sandakov Ya. P. , Mistiakov M. V. , Berezina M. V. 
Published: January 2022

Background: Structural and metabolic disorders of bone tissue in women with T2DM have no clinical manifestations, but they are accompanied by the risk of fractures.Aim: To study the parameters of bone metabolism, BMD and microarchitectonics in female patients with T2DM in the Buryat population.Materials and methods: The observational single-center one-stage controlled study included 73 women with T2DM, which were divided into 2 groups depending on the functional state of the ovaries (reproductive and postmenopausal periods). In each group, subgroups of the Buryat and Russian populations were identified. The first group included 34 patients with T2DM of the reproductive period: 16 from the Buryat population and 18 from the Russian population. The second group consisted of 39 postmenopausal patients with T2DM: 17 from the Buryat population and 22 from the Russian population. The study of BMD in the lumbar spine (L1-L4), femoral neck (Neck), in the proximal femur (Total hip), trabecular bone score (TBS), serum osteocalcin (OC), N-terminal propeptide type 1 procollagen was carried out (P1NP), vitamin D 25 (OH), blood plasma type I collagen C-terminal telopeptide (β-Cross laps) and ionized calcium (iCa).Results: In female patients with T2DM of the reproductive age of the Buryat population, an increase in both markers of osteosynthesis P1NP (p=0.035), OC (p=0.047), and bone resorption β-Cross laps (p=0.040) was found relative to the similar group of the Russian population. In women with T2DM in the postmenopausal period of the Buryat population, there was also an increase in P1NP (p = 0.016), OC (p = 0.048), β-Cross laps (p = 0.020) compared with the group of postmenopausal women in the Russian population. Structural disorders, characterized by a decrease in TBS, were detected only in the postmenopausal period in female patients of the Buryat population compared to women in the Russian population (p = 0.029).Comparative analysis among women with T2DM of the Buryat population, depending on the functional state of the ovaries, showed that activation of bone remodeling with an increase in P1NP (p = 0.019), OC (p = 0.004) and β-Cross laps (p = 0.004) is characteristic of postmenopausal women accompanied by a decrease in BMD Neck (p = 0.006), BMD Total hip (p = 0.003), BMD L1-L4 (p = 0.049) and TBS (p = 0.020) relative to female patients with T2DM in the reproductive period.Conclusion: In women with T2DM in the Buryat population, both in the reproductive and postmenopausal periods, an increase in bone remodeling markers and BMD stability was found when compared with the corresponding groups of patients in the Russian population. The postmenopausal period was characterized by an additional decrease in TBS in patients with T2DM in the Buryat population relative to women in the Russian population.
Practical Identity, Contingency and Humanity
Authors: Ranzenigo Damiano 
Published: January 2022

Abstract
Aim of this paper is to support the view that all human practical identities are contingent by arguing against the view that there is at least one necessary practical identity shared by all human beings, namely Humanity. The view that Humanity is a necessary practical identity is explicitly defended by Christine M. Korsgaard (Korsgaard, C. M. 1996. The Sources of Normativity, edited by O. O’Neill. Cambridge: Cambridge University Press; Korsgaard, C. M. 2009. Self-Constitution: Agency, Identity, and Integrity. New York: Oxford University Press) and indirectly by Marya Schechtman (Schechtman, M. 2014. Staying Alive: Personal Identity, Practical Concerns, and the Unity of a Life. New York: Oxford University Press). Korsgaard understands Humanity both in terms of pure self-legislation, and as deep sociality. In the first case, Humanity as self-legislation faces what I call ‘Existential dilemma’: either Humanity has specific content, typical of contingent practical identities, but stops being necessary for all human beings; or Humanity is emptied of its content and is conceived of as necessary self-legislation, but stops being a practical identity. In the second case, i.e., Humanity as deep sociality, Korsgaard confuses the necessary natural fact that human beings are social creatures, with contingent contexts of human socialization, which are the true sources of specifically human practical identities. I articulate this confusion in the guise of what I call ‘Nature/Nurture dilemma’, which also applies to the morally neutral account of human personhood advocated by Schechtman (Schechtman, M. 2014. Staying Alive: Personal Identity, Practical Concerns, and the Unity of a Life. Oxford University Press). In conclusion, I address the worry that without the necessary practical identity of Humanity we might not be able to extend our practical and moral concerns to distant fellow human beings by sketching an alternative path to extend such concerns.
The anisotropic broadband surface plasmon polariton and hot carrier properties of borophene monolayer
Authors: Jian Chaochao , Ma Xiangchao , Zhang Jianqi , Jiang Jiali 
Published: January 2022

Abstract
Borophene monolayer with its intrinsic metallic and anisotropic band structures exhibits extraordinary electronic, optical, and transport properties. Especially, the high density of Dirac electrons enables promising applications for building low-loss broadband SPP devices. However, a systematic characterization of the surface plasmon polariton (SPP) properties and hot carriers generated from the inevitable SPP decay in borophene has not been reported so far. Most importantly, the mechanism for SPP losses remains obscurely quantified. In this work, from a fully first-principles perspective, we explicitly evaluate the main loss effects of SPP in borophene, including the Drude resistance, phonon-assisted intraband and direct interband electronic transitions. With this knowledge, we further calculate the frequency- and polarization-dependent SPP response of borophene, and evaluate some typical application-dependent figure of merits of SPP. On the other hand, we evaluate the generation and transport properties of plasmon-driven hot carriers in borophene, involving energy- and momentum-dependent carrier lifetimes and mean free paths, which provide deeper insight toward the transport of hot carriers at the nanoscale. These results indicate that borophene has promising applications in next-generation low-loss optoelectronic devices and photocatalytic reactors.
Mountain-Expressway Slope Safety Based on the Online Monitoring System and Fuzzy Comprehensive Evaluation
Authors: Yao Aijun , Gong Yifei , Li Yanlin , Tian Tian , Xu Chengshun 
Published: January 2022

Abstract
Mountainous highway slopes are characterized by their point-like distribution, large number, relatively small scale, and susceptibility to human activities and environmental changes. Overall monitoring and assessment of slopes are necessary to detect hazards in a timely manner and prepare disaster prevention measures in advance. There is a lack of integration and utilization of monitoring data, and the slope safety evaluation system is not mature. In response to these problems, this study uses real-time monitoring data of highway slopes as the research object. Real-time monitoring data of multisource monitoring indicators are used to evaluate and provide early warning on the degree of safety of the highway slopes. The main research includes the following: (1) Construction of an online monitoring system for highway slopes. This study analyzes the sensitivity of the slope’s influencing factors and the deformation characteristics of slopes along mountainous highway slopes. The application principles of monitoring indicators, points, and monitoring networks are created. (2) Highway slope stability evaluation hierarchical models are generated from monitoring the index layer to the judgment criterion layer based on multisource monitoring indexes. According to the analytic hierarchy process–fuzzy comprehensive evaluation methods, the real-time stability level of the slopes is determined on the basis of the stability assessment data set. (3) A real-time evaluation model was applied to the stability evaluation of slopes. The established model is suitable for stability evaluation and security classification of highway slopes in mountain areas. From the evaluation results, heavy rainfall is the main reason for the safety level reduction of slopes in mountain areas. According to monitoring items, the system can evaluate the safety level of slopes and monitor the subsidence of mountain highway subgrades and geological disasters, such as landslides and collapses, along mountain highways in real time.
Gender Distribution of Scholarship and Measures of National Recognition in Hospital Medicine
Authors: Kim Juliann L. , Allan Jessica M. , Fromme H. Barrett , Forster Catherine S. , Shaughnessy Erin , Ralston Shawn 
Published: January 2022

OBJECTIVE
Our specific aim was to assess the gender distribution of aspects of scholarly productivity and professional standing for pediatric hospital medicine over a 5-year period. We also evaluated for correlation between the makeup of editorial boards, conference planning committees, and chosen content.

METHODS
We reviewed scholarly publications, presentations, editorial boards, planning committees, awardees, and society leadership in pediatric hospital medicine from 2015 to 2019 and determined gender using published methods to assess for differences between observed proportions of women authors and presenters and the proportion of women in the field.

RESULTS
The field of pediatric hospital medicine at large is 69% women (95% confidence internal [CI] 68%–71%), and an estimated 57% of senior members are women (95% CI 54%–60%). We evaluated 570 original science manuscripts and found 67% (95% CI 63%–71%) women first authors and 49% (95% CI 44%–53%) women senior authors. We evaluated 1093 presentations at national conferences and found 69% (95% CI 65%–72%) women presenters of submitted content and 44% (95% CI 37%–51%) women presenters of invited content. Senior authorship and invited speaking engagements demonstrated disproportionately low representation of women when compared with senior members of the field (senior authorship, P = .002; invited presenters, P &lt; .001). Strong positive correlation between gender composition of conference planning committees and selected content was also noted (r = 0.94).

CONCLUSION
Our study demonstrated representative gender distribution for some aspects of scholarly productivity in pediatric hospital medicine; however, a lack of gender parity exists in senior roles.
Characteristics of the toxic effect of imidacloprid on the state of Eisenia fetida (Annelida, Clitellata, Lumbricidae)
Authors: Huslystyi A. O. , Gasso V. Y. , Yermolenko S. V. , Petrushevskyi V. B. 
Published: January 2022

Imidacloprid became the most sold neonicotinoid insecticide in the world in the 21st century. Due to their constant use, neonicotinoids are stored in soils, bottom deposits, and surface waters. It is known that neonicotinoids reveal toxicity for non-target species: annelid worms, insects, fish, birds, and mammals. Neonicotinoids exhibit reproductive toxicity, neuro-, hepato-, and genotoxicity for mammals. Earthworms are useful modeling organisms that are proposed to carry out toxicity tests. Eisenia fetida is considered a convenient and adequate species in toxicological studies. Analysis of available data shows that even low concentrations of imidacloprid caused protrusion of a belt, blackening, leakage of a cellar fluid, narrowing areas of the body with edema in segments, and dark body pigmentation in E. fetida. There are also biochemical changes. Low concentrations of imidacloprid (<0.2 mg/L) suppress the activity of cellulase. Imidacloprid also causes damage to DNA, production of reactive oxygen species, and alterations in antioxidant enzymes activity in E. fetida: inhibition of catalase, but activation of superoxide dismutase and glutathione-S-transferase. Imidacloprid reduces reproductive success in E. fetida, causing significant deformation of sperm, reducing the average number and size of cocoons and the success of birth. At concentrations ≥10 mg/kg of imidacloprid, the high mortality of worms makes it impossible for vermiculture. At 5 mg/kg of imidacloprid in plants remains for vermicomposting in seven weeks, the mortality rate of 25% of E. fetida individuals is fixed. The stereotypical escape reflex behavior in the worms was observed in relation to imidacloprid at a concentration of 1.32 mg/kg. At the same time, molecular and cellular mechanisms of toxic effects of imidacloprid on E. fetida are almost not studied and needed special attention with further research.
Assessment of adaptive capacity of native and adventive species of trees and shrubs in Dnipro region
Authors: Ivanko I. A. , Kulik A. F. 
Published: January 2022

Nowadays, deterioration and loss of ecological functions of urban tree and shrub plantations take place in Europe and, in particular, in Ukraine; it was noted that their number is insufficient to counteract the negative impact of global climate change and protect the population against industrial pollution effects. The issue of resistance of native and adventitious tree species used in the plantations of industrial cities remains relevant; it necessitates the assessment of physiological and biochemical aspects of their adaptation to extreme environmental factors, such as moisture limit in the steppe zone, periodic dangerously low winter temperatures and anthropo-technogenic load (in large urban agglomerations). In order to optimize the assortment of tree species of large megalopolises of the steppe zone of Ukraine and determine their potential resistance to anthropogenic pressures the study was conducted in conditionally clean forest biogeocenoses of the Samara River levee zone and in artificial plantations on the territories located in the coastal zone of the Dnipro River within 1500 m from the Prydneprovskaya thermal electric station (PTES, Dnipro city). It well known that the TPP is the source of atmospheric air pollution by such heavy metals as lead and cadmium. A study of the activity of antioxidant protection enzymes in leaves of native and adventive tree species showed that in the zone of Prydneprovskaya TES impact there was an increase of guaiacol peroxidase activity in Acer platanoides, Ulmus minor, Morus alba; benzidine peroxidase in Acer negundo, Ulmus laevis, Acer platanoides; catalase in A. platanoides, A. negundo, U. laevis, Ulmus pumila and Robinia pseudoasasia. High peroxidase activity, which is complemented by higher catalase activity, indicates the relative resistance of these species to atropo-technogenic pressures supported by antioxidant defense mechanisms. Total chlorophyll content (Chla + Chlb) in leaves of native species Ulmus laevis, Acer platanoides and adventive Morus alba decreased in the zone of TPP impact in relation to conditionally clean areas. The ratio of chlorophyll a to chlorophyll b in contaminated areas significantly increased in leaves of native species Ulmus laevis, Ulmus minor, Acer platanoides compared with control. The invasive species Acer negundo, Morus alba, Ulmus pumila had no significant changes in this indicator. In invasive species such as Ulmus pumila, Acer negundo there was an increase in leaf mass, which may indicate adaptation of these species to anthropogenically altered growth conditions.
Percepciones e intención de los padres de vacunar a sus hijos menores de 12 años contra la COVID-19: Estudio transversal en Perú
Authors: Zamora Jose Gonzales , Moreno David Soriano , Soriano Anderson , Ponce-Rosas Linda , De-Los-Ríos-Pinto Abraham , Murrieta-Ruiz Valentina , Morocho-Alburqueque Noelia , Caira-Chuquineyra Brenda , Alave-Rosas Jorge 
Published: January 2022

Objetivos: Evaluar las percepciones e intención de los padres de vacunar a sus hijos menores de 12 años en Perú.
Metodología: Estudio transversal analítico a partir de una encuesta en línea (25 de noviembre al 6 de diciembre del 2021) para padres de niños menores de 12 años que recopiló la percepción sobre el riesgo de contagio por COVID-19 en sus hijos, sobre la necesidad de vacunación y sobre los eventos adversos relacionados con la vacuna. Evaluamos los factores asociados a la intención de vacunación mediante razones de prevalencia crudas (RPc) y ajustadas (RPa) con intervalos de confianza al 95% (IC 95%).
Resultados: El 83.5% de los padres tenían la intención de vacunar a sus hijos menores de 12 años. En el análisis multivariado, los factores asociados a una disminución de la intención de vacunación fueron pensar que la vacuna no es necesaria (RPa: 0.65; IC 95% 0.44 – 0,94), que no protegería (RPa: 0.14; IC 95% 0.03 – 0.63), que no sería segura (RPa: 0.80; IC 95% 0.70 – 0.92) y que ocasionaría efectos negativos a largo plazo (RPa: 0.92; IC 95% 0.85 – 1.00). Por otro lado, residir en la Selva (RPa: 1.09; IC 95%: 1.03 – 1.15) o en la Sierra (RPa: 1.06; IC 95%: 1.00 – 1.11) se asoció a una mayor prevalencia de intención.
Conclusiones: En Perú, un 16.5% de padres no vacunaría a sus hijos menores de 12 años, ya que perciben que la vacuna no es necesaria y no protegería contra la COVID-19, además de tener la preocupación de posibles eventos adversos.
PEDAGOGIAS E PERFORMANCES CORPORAIS E SEXUAIS DE HOMENS GAYS NO TWITTER
Authors: Desidério Ricardo , Couto Edvaldo Souza 
Published: January 2022

O Twitter, enquanto artefato cultural, permite a seus usuários postagens informativas, mas também abordagens sexuais e pornográficas. Neste contexto, a partir dos aportes teóricos dos estudos culturais na educação e dos estudos de redes sociais na educação, o artigo apresenta resultados de uma pesquisa cujo objetivo foi analisar como são construídas as performances corporais e sexuais de um grupo de homens gays no Twitter, destacando discursos e pedagogias que educam o olhar por meio destas interações em rede. O método usado foi o qualitativo, de cunho descritivo e analítico, numa perspectiva dos estudos de redes sociais, numa abordagem da etnografia virtual. Os resultados apontam que os perfis analisados evidenciam a exibição performática dos corpos, dos órgãos sexuais e de discursos que ressaltam sexualidades construídas em e para as telas. Tais performances são repletas de pedagogias que orientam modos de ser gay e a educação do olhar na era das conectividades.
Deploying an Artificial Intelligence‐based defect finder for manufacturing quality management
Authors: Lee Kyoung Jun , Kwon Jun Woo , Min Soohong , Yoon Jungho 
Published: January 2022

AbstractThis paper describes how the Big Data Research Center of Kyung Hee University and Benple Inc. developed and deployed an artificial intelligence system to automate the quality management process for Frontec, an SME company that manufactures automobile parts. Various constraints, such as response time requirements and the limited computing resources available, needed to be considered in this project. Defect finders using large‐scale images are expected to classify weld nuts within 0.2 s with an accuracy rate of over 95%. Our system uses Circular Hough Transform for preprocessing as well as an adjusted VGG (Visual Geometry Group) model. Our convolutional neural network (CNN) system shows an accuracy of over 99% and a response time of about 0.14 s. To embed the CNN model into the factory, we reimplemented the preprocessing modules using LabVIEW and had the classification model server communicate with an existing vision inspector. We share our lessons from this experience by explaining the procedure and real‐world issues developing and embedding a deep learning framework in an existing manufacturing environment without implementing any hardware changes.
Optimizing smart grid operations from the demand side
Authors: Zheng Yongqing , Yu Han , Shi Yuliang , Zhang Kun , Zhen Shuai , Cui Lizhen , Leung Cyril , Miao Chunyan 
Published: January 2022

AbstractAs demand for electricity grows in China, the existing power grid is coming under increasing pressure. Expansion of power generation and delivery capacities across the country requires years of planning and construction. In the meantime, to ensure safe operation of the power grid, it is important to coordinate and optimize the demand side usage. In this paper, we report on our experience deploying an artificial intelligence (AI)–empowered demand‐side management platform – the Power Intelligent Decision Support (PIDS) platform – in Shandong Province, China. It consists of three main components: 1) short‐term power consumption gap prediction, 2) fine‐grained Demand Response (DR) with optimal power adjustment planning, and 3) Orderly Power Utilization (OPU) recommendations to ensure stable operation while minimizing power disruptions and improving fair treatment of participating companies. PIDS has been deployed since August 2018. It is helping over 400 companies optimize their power usage through DR, while dynamically managing the OPU process for around 10,000 companies. Compared to the previous system, power outage under PIDS due to forced shutdown has been reduced from 16% to 0.56%.