bluuebunny/crossref_metadata_2025_split huggingface dataset:
A multidisciplinary learning approach: training, preparation and role transition
Authors: Hulse Anna Louise 
Published: April 2022

The review in part 1 identified that, although studies address global differences in advanced practice roles, there is limited literature regarding training preparation and role transition, highlighting a gap in educational research. Aim: To explore trainee and qualified advanced practitioner learning experiences, how training has prepared learners for clinical practice and role transition. Evaluation of a multidisciplinary learning approach was sought, identifying its impact on developing collaborative learning and working partnerships. Design and methods: A small-scale, mixed-methods cross-sectional study was used to gather descriptive data. Convenience sampling was used with two groups: trainees and qualified advanced (paediatric) nurse practitioners/advanced clinical practitioners (ANPs/ACPs). All participants had completed or were undertaking master's level training. An anonymous, voluntary online survey was used to gather quantitative and qualitative data reflecting participant learning experiences. Evaluation research methodologies and their application were examined through exploration of three advanced practice frameworks and a well-established framework for evaluation of training. Findings: Overall, responses indicate positive learning experiences, and that current and previous ANP/ACP training in the UK does adequately prepare trainees for practice. However, further improvements in curriculum content are suggested. Consistent with the literature, collaborative multidisciplinary teaching, learning and mentorship were identified as key elements in the learning process and role transition.
A indesejada das gentes: entre a literatura e a necropolítica
Authors: Dias Denise , Soares de Souza Lícia 
Published: April 2022

Este artigo investiga as obras de Jorge Amado, Tereza Batista cansada de guerra, 1972; de Moacyr Scliar, Sonhos Tropicais, 1992; de Pedro Nava, Chão de ferro, 2012; as quais suscitam o testemunho do caos social promovido por epidemias durante o século XX. A partir da leitura dos referidos romances, visualizamos essas doenças como metáforas da exclusão social, isso é observável no conteúdo e pano de fundo que descortinam as mazelas e efeitos sociais causados por elas, especialmente em grupos sociais vulneráveis e menos assistidos pelo poder público. Os escritores lidos fizeram de sua experiência com a literatura um modo de entender o Brasil; por isso, essas obras conduzem o leitor a refletir, de maneira geral, sobre o contexto histórico brasileiro principalmente pelo viés histórico-cultural e sanitário. Assim, nosso objetivo foi investigar de que forma os autores estabelecem, nas obras do corpus, uma discussão em torno da dimensão limítrofe entre vida e morte, explicitando a necropolítica, termo cunhado por Aquille Mbembe, o qual afere que o Estado tem o poder de decidir quem morre e quem vive, a depender de como as políticas públicos vigoram no meio social. O método utilizado, durante a investigação, toma por base os textos teóricos dos filósofos Michel Foucault, Giorgio Agamben e Aquille Mbembe. Os resultados demonstram, via literatura, que o Estado utiliza-se de estratégias de políticas excludentes, fatos demonstrados nas obras em questão, cujo retrato apresenta um país historicamente marcado pelo caos social.

Palavras-chave: Biopoder; Necropolítica; Epidemia; Literatura.
Estéticas da Necropolítica no Brasil e no Québec: Crítica da Razão de Exclusão
Authors: Soares de Souza Licia 
Published: April 2022

Este texto está em forma de projeto visando a analisar obras das literaturas quebequense e brasileira que põem em cena condições precárias de vida, como “zonas de inimizade” de um estado neoliberal que pouco se preocupa com o bem-estar de seus cidadãos. A Estética da necropolítica se inspira das noções de biopoder de Foucault (1979) e de necropolítica de Mbembe (2014/16), tentando trazer a discussão para os espaços das Américas onde vários grupos sociais são submetidos a condições de vida arriscadas que lhes confere o status de “mortos-vivos”. Nesse sentido, no entre-lugar dos centros urbanos organizados e das periferias negligenciadas pelos poderes públicos (favelas, trapiches, lazaretos, asilos, cárceres, matas, metrôs, etc.) quer-se mapear, analisar e classificar, de acordo com as diferentes estratégias que determinam, de um lado, a crítica da razão da exclusão, em situação transtextual e transacional, e, de outro lado, as mobilidades nos espaços semiosféricos que permitem a ultrapassagem das zonas necropolíticas para as zonas do discurso oficial. A crise da Covid-19 propiciou o escancaramento do projeto neoliberal de aniquilamento das populações carentes, negros, indígenas, migrantes, trabalhadores informais, etc. Nesse caso, busca-se proceder, à luz dos pressupostos da literatura comparada interamericana, ao levantamento e à análise de obras produzidas nos séculos XX e XXI, no contexto híbrido das Américas. Põem-se em evidência obras do Québec (Catherine Mavrikakis (2016), Henri Lamoureux (2003), France Théoret (2006) e do Brasil (Jorge Amado 1937/82), Moacyr Scliar (1992), Márcio Souza (1983)), que revelam muitas zonas de necropolítica que a história foi incapaz de evidenciar. Esta é a Crítica da Razão de Exclusão que pretendemos sistematizar com a análise do presente projeto.

Palavras-chave: Necropolítica. Biopoder. Exclusão. Literatura Quebequense. Literatura Brasileira. Semiosfera. Texto-xadrez.
L’initiation à la recherche scientifique à l’école : les littératures francophones dans une perspective citoyenne
Authors: Passos Moraes Luciano 
Published: April 2022

Résumé: Le débat autour de la place des littératures dans l’enseignement de base est encore peu exploré puisque la littérature en général occupe un espace assez restreint dans les salles de classe de langues. Si l’on regarde de plus près la réalité de l’enseignement de français au Brésil, il reste clair que l’espace voué aux littératures francophones est presque inexistant. C’est pourquoi nous proposons de repenser l’importance du littéraire dans la formation des étudiants à l’école publique puisque la littérature est un moyen riche en possibilités d’exploration de questions historiques et sociales. Comme possibilité de remédier l’absence des littératures francophones dans les programmes traditionnels, les projets d’initiation à la recherche scientifique peuvent aider à surmonter cette réalité tout en mettant en relief des écrivains et des écrivaines qui n’appartiennent pas à l’Hexagone et qui sont souvent exclu(e)s du canon dominant.
Mots clés: littératures francophones ; littératures migrantes ; littératures transnationales ; français langue étrangère ; initiation à la recherche scientifique
Personalized Reimbursement Model (PRM) program: A real-world data platform of cancer drugs use to improve and personalize drug pricing and reimbursement in France
Authors: Squara Pierre-Alexandre , Luu Vinh-Phuc , Pérol David , Coudert Bruno , Machuron Valérie , Bachot Camille , Samelson Laurence , Florentin Virginie , Pinguet Jean-Marc , Ben Hadj Yahia Béchir 
Published: April 2022

Objective
This article describes the Personalized Reimbursement Model (PRM) program methodology, limitations, achievement and perspectives in using real-world data of cancer drugs use to improve and personalize drug pricing and reimbursement in France.

Materials and methods
PRM platform aggregates Electronic Pharmacy Records (EPR) data from French medical centers (PRM centers) to build retrospective cohorts of patients treated with injectable cancer drugs in a hospital setting. Data extracted on January 1st, 2020, from breast cancer (BC) patients who received trastuzumab, trastuzumab emtansin or pertuzumab since January 1st, 2011, and from lung cancer (LC) patients who received bevacizumab or atezolizumab since January 1st, 2015, enabled recovering their injectable cancer drugs history from diagnosis date until December 30th, 2019, and served as dataset for assessment.

Results
123 PRM centers provided data from 30,730 patients (25,660 BC and 5,070 LC patients respectively). Overall, 20,942 (82%) of BC and 4,716 (93%) of LC patients were analyzed. Completion rate was above 98% for patients characteristics, diagnostic and treatment related data. PRM centers cover 48% and 33% of BC and LC patients in-hospital therapeutic management in France, respectively. Distribution of BC and LC patients therapeutic management, by medical center category and geographic location, was similar in PRM centers to all French medical centers, ensuring the representativeness of the PRM platform.

Conclusion
PRM Platform enabled building a national database generating on demand Real-World Evidence based on EPR. This enabled the first performance-based risk-sharing arrangements based on PRM data, between the CEPS and Roche, for atezolizumab cancer immunotherapy in metastatic non-small cell lung cancer indication.
Recommendations for the pharmacological treatment of treatment-resistant depression: A systematic review protocol
Authors: Gabriel Franciele Cordeiro , Stein Airton Tetelbom , de Melo Daniela Oliveira , Fontes-Mota Géssica Caroline Henrique , dos Santos Itamires Benício , Rodrigues Camila da Silva , Rodrigues Mônica Cristiane , Fráguas Renério , Florez Ivan D. , Correia Diogo Telles , Ribeiro Eliane 
Published: April 2022

Introduction
Depression is a serious and widespread mental health disorder. Although effective treatment does exist, a significant proportion of patients with depression fail to respond to antidepressant treatment trials, a condition named treatment-resistant depression. Efficient approach should be given this condition in order to revert the burden caused by depression. Clinical practice guidelines (CPGs) are evidence-based health promotion instruments to improve diagnosis and treatment. CPGs recommendations for treatment-resistant depression must be trustworthy. The objective of the proposed study is to systematically identify, appraise the quality of CPGs for the treatment of depression and elaborate a synthesis of recommendations for treatment-resistant depression of CPGs considered to be of high quality and with high quality recommendations.

Methods and analysis
We will search the databases of organizations, such as PubMed, Embase, Cochrane Library, PsycInfo, and the Virtual Health Library, and organizations that develop CPGs. Three independent researchers will assess the quality of the CPGs and their recommendations using the AGREE II and AGREE-REX instruments, respectively. Given the identification of divergences and convergences as well as weak and strong points among high quality CPGs, our work may help developers, clinicians and eventually patients.

Ethics and dissemination
No ethical approval is required for a systematic review, as no patient data will be used. The research results will be disseminated in conferences and submitted to a peer reviewed journal.
Integrating Local Wisdom into ELT Materials for Secondary School Students in Semarang
Authors: Wulandari Dwi , Sundari Wiwiek , Ellysafny Cut Aja Puan 
Published: April 2022

This study is Research & Development which contains three phases (explorative, model design, and try-out). The research aims to develop a teaching material which integrates Javanese local wisdom for the students of secondary school in Semarang. Phase 1 (the explorative study) consists of two parts: book review and needs analysis (questionnaire and interview). The results of the first phase show that the existing three books do not include aspects of local wisdom. While the needs analysis show that the respondents agreed to integrate aspects of local wisdom with the benefits as follows: (a) supporting the learning process, (b) making the students understand the materials more easily, (c) enhancing the understanding of local cultures and character education. In phase 2 and phase 3 (model design and try-out in three schools), the findings indicate that integrating local wisdom, i.e. a traditional song ”menthog-menthog” can enliven the classroom atmosphere. In addition, based on the respondent perception, the integration of local wisdom would enrich the knowledge of local cultures as well as help the students understand ELT texts.
Enhancing the implementation of bilingual education at university through practice: Analysis of CLIL trial lessons by an ESP teacher
Authors: Contero Urgal Candela 
Published: April 2022

University teacher training specialised in bilingual education is spreading around Spanish universities. Particularly in Andalusia, where our research originates, universities are searching for systematised methods to train their future bilingual teachers in Content and Language Integrated Learning (CLIL). This paper presents the case of the University of Cadiz, where this study was carried out. This university followed a new training formula led by an ESP (English for Specific Purposes) teacher who performed the role of CLIL teacher trainer. Based on AUTHOR’s (2017) description of the aforesaid CLIL teacher training scheme known as “CLILUT courses” (that is to say, CLIL Training or University Teachers), this study focuses on an in-depth analysis of CLIL trial lesson plans elaborated within such a peer-teacher environment. The present study is then aimed at examining the data obtained through in-class direct observation of 68 CLIL trial lessons which were created from 2010 to 2014 at the University of Cádiz and analysed with the help of rubrics created upon Nunan’s theory (1989). Results show that ESP teachers can offer substantial help for new CLIL university teachers who might face specific foreign language-related problems when starting to take part in bilingual programmes.
Defining Appropriate Curriculum for English Diploma Program
Authors: Wulandari Dwi 
Published: April 2022

This study is aiming at looking at the appropriate curriculum for Diploma Program in English by focusing on the targetted competence and the unique feature of the program. As a vocational school, English diploma program is facing problems in defining its own characteristics. The so far called diploma program is actually the shorthened term of the undergraduate English program with the absence of literary and linguistics related courses, and focused merely on the English skill learning. Although some practical skills other than English have been embedded in the curriculum, such as the additional courses in tourism and public relations, still the program missed the answer for its basic question; what the targetted competence and the unique feature of the program are. This research is done in trying to find the answer by doing both library research trying to take a look the ideal features of English Diploma programs, and interview trying to see the nature and the specific goal targetted by the management in handling the programs as well as the difficulties to match the present condition with the ideal one. The study reveals that some of English diploma programs may face the same issue of not being clear in targetting the competence as the vocational program, although some have found what is being idealized.
On the sharp lower bounds of modular invariants and fractional Dehn twist coefficients
Authors: Liu Xiao-Lei , Tan Sheng-Li 
Published: April 2022

Abstract
Modular invariants
of families of curves are Arakelov invariants in arithmetic algebraic geometry. All the known uniform lower bounds of these invariants are not sharp. In this paper, we aim to give explicit lower bounds of modular invariants of families of curves, which is sharp for genus 2. According to the relation between fractional Dehn twists and modular invariants, we give the sharp lower bounds of fractional Dehn twist coefficients and classify pseudo-periodic maps with minimal coefficients for genus 2 and 3 firstly. We also obtain a rigidity property for families with minimal modular invariants, and other applications.
Exploring the discourse of enterprise cyber governance in the covid-19 era: a sociosemiotic perspective
Authors: Chunlei Si , Yuxin Liu 
Published: April 2022

Abstract
This corpus-based study conducts detailed discourse analysis in the domain of enterprise cyber governance in the covid-19 era, with a self-built corpus containing textual discourse resources from nine typical digital technology companies and a reference corpus containing related official publications of the U.S. and the EU. Employing Fairclough’s three-dimensional model with steps of description, interpretation and explanation as the analytical framework, the authors investigate the discourse construction process for cyber governance in the business environment after the breakout of covid-19 epidemic. Based on theme and sample analysis, it is shown that the main concerns of the enterprise cyber governance discourse in the covid-19 era contain data breaches, information security, products and services, customers’ privacy and cyber espionage, and enterprises utilize a series of discursive strategies to (re)contextualize the linguistic realization. Combined with Halliday’s sociosemiotic theory, certain discursive practices are further explained in the social semiotic system as a whole, including the tenor, field and mode under the context of covid-19 epidemic. The contextual analysis proves that such strategies serve as the channels to legitimate the authority of the addressors (enterprises) over the cybersecurity of the main addressees (customers), which is further realized in certain context (situation), including two types of bidirectional relationships enterprises, customers and governments. The findings confirm that the linkage between a signifier and its signified can be realized by contextualization and (re)contextualization, and certain discourse can be materially realized by integrating the semiotic resources in the broader social context. This interdisciplinary study not only provides valuable insights for the domain of discourse and sociosemiotic studies, but also creates a new approach to the studies of cyber governance in the synchronic context.
The equivalent condition of G-asymptotic tracking property and G-Lipschitz tracking property
Authors: Ji Zhanjiang 
Published: April 2022

Abstract
In this paper, we introduce the concepts of

G

G

-Lipschitz tracking property and

G

G

-asymptotic tracking property in metric

G

G

-space and obtain the equivalent conditions of

G

G

-asymptotic tracking property in metric

G

G

-space. In addition, we prove that the self-map

f

f

has the

G

G

-Lipschitz tracking property if and only if the shift map

σ

\sigma

has the

G

¯

\overline{G}

-Lipschitz tracking property in the inverse limit space under the topological group action. These results generalize the corresponding results in [Proc. Amer. Math. Soc. 115 (1992), 573–580].
Antibacterial, antioxidant and cytotoxic activities of the stem bark of Archidendron jiringa (Jack) I.C. Nielsen
Authors: Noviany Noviany , Hasanah Uswatun , Lotulung Puspa Dewi , Hadi Sutopo 
Published: April 2022

Abstract

Archidendron jiringa (Jack) I.C. Nielsen plant, locally known as jengkol, is a species belongs to Archidendron genus of the Fabaceae family. This plant is a potential source of biologically active secondary metabolites, which are useful for various purposes, such as to destroy bacteria and fungi, to treat cancer, and as antioxidant agent. In this study, extract of A. jiringa stem bark was fractionated and subsequently tested for antibacterial, cytotoxic and antioxidant activity. Extraction was carried out using maceration and fractionation of the extract was conducted using both vacuum liquid and column chromatography techniques to obtain three fractions. The biological activity of the bulk extract and fractions were then evaluated using disc diffusion method, revealing that the sample with the highest activity against Bacillus subtilis and Escherichia coli is the ethyl acetate extract, while no inhibitory effect on both bacteria was observed for some ethyl acetate fractions tested. The screening tests indicate that the bulk extract and all fractions exhibit promising toxicity, with the LC50 values in the range of 227–837 ppm. In addition, good antioxidant activities, with the IC50 values in the range of 0.7–7.2 ppm, are displayed by bulk extract and the fractions.
SÜLEYMAN DEMİREL ÜNİVERSİTESİ HASTANESİNDE COVID-19 YÖNETİMİ: BİR PANDEMİNİN İKİNCİ YIL KRONOLOJİSİ
Authors: YAZKAN Rasih , ŞENGEZE Nihat , ZİHNİ İsmail , ERDOĞAN Mehmet , SÖZEN İsa , ŞENOL Nilgün 
Published: April 2022

Pandemi henüz bitmiş değildir, pandeminin ikinci yılı
özellikle delta ve omicron varyantlarının, özellikle ikinci
yarısı da normalleşme kararlarının etkisi altında
geçti. Toplumsal uyumun bu süreçteki tartışmasız tek
doğru olduğu gerçeği hem Türkiye hem de Dünya için
değişmedi.
Tata Kelola Kearsipan dan Kinerja Pemerintah Daerah : Penyusutan Arsip Pemerintah Kabupaten Sleman Tahun 2021
Authors: Krisnawati Krisnawati 
Published: April 2022

Penyusutan arsip dalam suatu organisasi atau instansi harus dilakukan untuk tujuan efisiensi dalam kinerja organisasi. Penyusutan arsip juga berfungsi untuk mengurangi arsip in aktif yang tidak memiliki nilai guna arsip. Penyusutan arsip mempunyai tiga tahapan, yaitu pemindahan arsip, penyerahan dan pemusnahan. Tujuan dari penelitian ini adalah untuk mendeskripsikan proses optimalisasi penyusutan arsip di Dinas Perpustakaan dan Kearsipan, termasuk di dalamnya faktor pendukung dan penghambatnya, serta penyusutan arsip yang berdampak pada kinerja Pemerintah Daerah. Metode penelitian yang digunakan adalah kualitatif, dimana peneliti ikut terlibat secara langsung sebagai instrumen penelitian. Hasil dari penyusutan bisa berupa non arsip yang nantinya bisa dilanjutkan proses pemusnahan arsip, arsip yang masih harus disimpan karena masih dipergunakan dalam kegiatan organisasi meskipun nilai gunanya sudah menurun (arsip dinamis in aktif) ataupun berupa produk arsip statis yang bersifat permanen dan tidak bisa dimusnahkan. Arsip statis inilah yang bisa dijadikan salah satu indikator kinerja bagi pemerintah daerah sebagai bukti pelaksanaan kegiatan. Semakin banyak arsip statis yang tercipta maka semakin tinggi kinerja pemerintah daerah.
Stroke Risk Assessment and Emergency Mobile Application in a Hospital in Thailand
Authors: Pruitikanee Siwipa , Kongcharoen Jinda , Puttinaovarat Supattra , Yaifai Thotsaphon , Chaitada Sasikorn 
Published: April 2022

Background: Cerebrovascular diseases or stroke tend to cause high mortality in Thailand. An essential responsibility of a hospital is the development of medical care to support the safety of patients. For this purpose, a smartphone application was developed for the risk assessment and emergency system for stroke treatment in a hospital in Thailand.
Methods: The proposed application involved the risk assessment related to the occurrence of stroke evaluated by the health status and face image using analytical geometry and face detection technology. The social network Application Programming Interface (API), LINE Notify API, and Global Positioning System (GPS) were used to inform the Stroke team in the Suratthani hospital about emergency cases, followed their requirement in 2020.
Results: From the testing, the facial angulation classification, calculated using a support vector machine (SVM), had 92.38% accuracy. The system also provided an emergency call and text messaging that includes patient’s current location and personal information to the stroke team directly, which gave an opportunity for the patient to receive treatment quickly.
Conclusion: The emergency system can help quickly perform the risk assessment of stroke. Our proposed system provides automated management.