bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of Early Neurological Deterioration Following Intravenous Thrombolysis
Authors: Nair Srikumar B. , Somarajan Deepthi , Pillai Rammohan K. , Balachandran Keerthi , Sathian Sona 
Published: March 2022

Background:
Prevention of early neurological deterioration (END) is becoming an important therapeutic target in acute ischemic stroke management. The aim of the study is to ascertain the causes and predictors of early neurological deterioration following thrombolysis and determine the predictive value of IScore.

Methods:
In this single center prospective study, we analyzed clinical, imaging and outcome data in 168 patients thrombolyzed intravenously ≤4.5 hours from onset of stroke. Early neurological deterioration was defined as worsening ≥2 points in the NIHSS score at 24 hours.

Results:
END occurred in 34 patients (20%) and caused significantly worse short term outcome. Ischemic END (ENDi) (n = 23) was twice as common as symptomatic hemorrhage (ENDh) (n = 11). Ischemia progression (n = 15) was the most common cause. Early malignant edema was another major cause. On multivariate analysis, significant predictors (p <.05) were proximal artery occlusion [all END (p <.001), ENDi and ENDh], previous ischemic insults (all END) and raised diastolic blood pressure (ENDh). ENDi was more common in those with carotid artery occlusion, large vessel disease and previous ischemic insults. ENDh was more common in those with raised diastolic blood pressure and NIHSS-ASPECTS mismatch. For patients with NIHSS <14, IScore >105 and for NIHSS ≥14, IScore >175 was associated with higher risk of END.

Conclusion:
END occurs in one fifth of patients after intravenous thrombolysis; ENDi outnumbers ENDh. Proximal artery occlusion is a major predictor for END. Potentially modifiable risk factors include admission hyperglycemia and elevated blood pressures. Distinct factors characterize ENDh and ENDi and can guide prevention and management strategies. IScore identifies patients at risk for END.
Correlation between foveal microvasculature and inner retinal layer thickness in type 2 diabetes
Authors: Al-Nashar Haitham Y. , Al-Bialy Hany A. 
Published: March 2022

Aim
The aim of this study was to evaluate the correlation between foveal microvasculature and inner retinal layer (IRL) thinning in patients with type 2 diabetes using optical coherence tomography angiography (OCTA).

Patients and methods
This is a prospective comparative study that included 100 eyes of 100 subjects: 50 eyes of diabetic patients with type 2 diabetes having mild to moderate nonproliferative diabetic retinopathy (NPDR) and 50 eyes of normal subjects. Foveal avascular zone (FAZ) area and vessel density of parafoveal and perifoveal areas were calculated using OCTA. The IRL thickness was measured using optical coherence tomography (OCT). The correlation between the IRL thickness and both FAZ area and macular vessel density was measured.

Results
The mean FAZ area was significantly larger in the NPDR group (0.69±0.01 mm2) than in the normal eyes group (0.45±0.02 mm2), (P=0.01). The mean parafoveal and perifoveal vessel density in the superficial capillary layer were significantly decreased in eyes with NPDR (46.7±6.5% and 43.8±7.1%, respectively) than in normal eyes (69.5±4.2% and 66.2±4.3%, respectively) (P=0.001). The mean parafoveal and perifoveal vessel density in the deep capillary layer had significantly lower values in eyes with NPDR (51.3±2.3% and 49.5±4.2%, respectively) than in normal eyes (70.1±5.4% and 68.3±3.73%, respectively), (P=0.001). The mean IRL thickness was significantly less in the NPDR eyes (54.7±6.8 μm) than in normal eyes (79.3±6.9 μm), (P=0.001). A statistically significant correlation was found between the IRL thickness and both FAZ area and macular vessel density in eyes with NPDR (P<0.001).

Conclusion
OCTA revealed that foveal microcirculatory alterations (FAZ area and macular vessel density) in diabetic eyes were related to the IRL thickness.
Primary open-angle glaucoma
Authors: Alhagaa Ahmed A. , Habib Rehab M. 
Published: March 2022

Aim
The aim of this study was to show if primary open-angle glaucoma (POAG) is associated with structural neurodegenerative changes along the visual pathway.

Patients and methods
The patients included in the study were divided into two groups: group 1 (200 patients having POAG) and group 2 (200 patients having no POAG as a control group). Brain MRI was done to evaluate the structural changes in the visual pathway.

Results
MRI brain showed that patients in group 1 have significantly lower optic nerve cross-sectional area (14±2.3 mm2) compared with group 2 (35±3.1 mm2) (P=0.012), and significantly lower lateral geniculate nucleus volume (58.4±4.7 mm3 in group 1 compared with 89.2±5.9 mm3 in group 2, P=0.009).

Conclusion
The pathology in POAG extended beyond the globe to involve the optic nerve cross-sectional area, and the lateral geniculate nucleus volume was significantly lower in patients with POAG. Such changes can be precisely detected with MRI. So, MRI can be considered as a tool for diagnosis and follow-up of patients with POAG.
Long-term results of artisan phakic intraocular lens in Egyptians
Authors: Eissa Iman M. , El Husseiny Mostafa A. 
Published: March 2022

Purpose
The aim of this study was to assess the long-term results of a sample of myopic Egyptian patients implanted with Artisan phakic intraocular lenses (PIOL).

Patients and methods
This is a retrospective longitudinal study that used data from 52 eyes of 28 patients implanted with anterior chamber iris-fixated Artisan PIOL. The postoperative assessment included refractive status, uncorrected visual acuity and best-corrected visual acuity, endothelial cell count, and the occurrence of complications for up to 15 years postoperatively.

Results
Higher postoperative uncorrected visual acuity (mean=0.519±0.195) and best-corrected visual acuity (mean=0.706±0.199), with improved spherical equivalent (from −12.06±2.004 to −0.74±0.9 D) and decreased endothelial cell count were all found to show statistically significant differences (P=0.007, 0.000, 0.000, and 0.007, respectively) when compared with the preoperative values. Males had a tendency for higher endothelial cell loss. The preoperative anterior chamber depth was correlated negatively with the endothelial cell loss percentage (P=0.019). An average yearly loss of 2.58% of endothelial cells was recorded following surgery. Few complications were recorded including cataract, glaucoma, and corneal decompensation.

Conclusion
Long-term results of Artisan PIOL implantation in Egypt showed a statistically significant visual improvement and good refractive correction with few complications but with significant endothelial cell loss.
Retinal nerve fiber layer thickness evaluation in iron deficiency anemia patients using optical coherence tomography
Authors: El-Gamal Shaza S.A. , Zaky Adel G. , El-Sawy Moataz F. 
Published: March 2022

Background
Anemia is a widespread public health problem. Iron deficiency is the most common cause of anemia. Hemoglobin (Hb) concentration was supposed to affect the retinal nerve fiber layer thickness (RNFLT).

Objective
The aim of this study was to evaluate the influence of iron deficiency anemia (IDA) on the peripapillary RNFLT using optical coherence tomography (OCT).

Patients and methods
A total of 30 patients with IDA with Hb less than 12 g/dl were enrolled in the study. Optic disk and RNFL parameters obtained by Topcon OCT in these patients were compared with those of age-matched and sex-matched nonanemic 30 individuals. The anemia group was also divided according to the Hb concentration into three groups: mild, moderate, and severe.

Results
The average age of the IDA cases and the controls was 23.38±9.06 years (range=15–30 years), and 25.37±7.64 years (range=15–30 years), respectively (P=0.09). The average right eye RNFLT in IDA patients was 98.20±10.98 µm compared with 106.30±14.05 µm in the control group (P=0.001), while in the left eye, it was 98.87±12.24 µm in the IDA group, and 105.30±6.59 µm in the control group (P=0.015). The average nasal and inferior RNFLT of the IDA group were thinner than the control group in the right eye (P=0.003 and 0.045, respectively) and in the left eye (P=0.016 and 0.038, respectively). There was a positive association between average RNFLT and Hb concentration in the right eye (r=0.554) and in the left eye (r=0.561), which was statistically significant (P=0.001). In addition, there was a positive correlation between nasal and inferior RNFLT and Hb concentration in the right eye (P=0.002 and 0.001, respectively) and in the left eye (P=0.001 and 0.002, respectively). The degree of thinning was related to the severity of anemia as the RNFL thinning was significantly more in severe anemia cases than in mild and moderate ones.

Conclusions
The peripapillary RNFLT measured by OCT was significantly thinner in the IDA patients in the average, inferior, and nasal quadrants, with more thinning in the severe than in mild and moderate groups. This finding may have a significant effect, as these pseudoglaucomatous changes could be misdiagnosed as glaucoma or other neuro-ophthalmological disorders.
A clinical study of ocular findings among patients with COVID-19 at a tertiary care center in Western Maharashtra, India
Authors: Gaikwad Rahul , Thikeker Mahesh , Kalantri Rama 
Published: March 2022

Background
More studies are required on the ocular manifestations of coronavirus disease 2019 (COVID-19) to help guide ophthalmologists to carefully screen these patients for early diagnosis, so that prompt management can be done to prevent further damage.

Aim
The aim of this study was to evaluate the ocular findings among patients with COVID-19 at a tertiary care center.

Patients and methods
A hospital record-based retrospective study was carried out on 1036 patients diagnosed with COVID-19 at a tertiary care center in Western Maharashtra, India. Visual acuity was measured at bedside by the finger-counting method or by using the Snellen's chart, if required. Anterior-segment eye examination was done on torchlight and binocular corneal loops, and slit-lamp biomicroscopy, as required. Extraocular movements were recorded in all nine gazes. Indirect ophthalmoscopy was done under full mydriasis.

Results
The age of the patients ranged from 4 to 98 years with a mean of 45.6±16.24 years. The majority (22.5%) of the patients belonged to the age group of 30–39 years. Males (61.8%) were more than females (38.2%). The ocular findings included congestion (16.8%), continuous conjunctival congestion (5.3%), vasculitic retinal-vein occlusion (8.7%), combined central retinal artery and vein occlusion (1.4%), central retinal-artery occlusion (0.8%), convergence insufficiency (8.4%), and lateral rectus paresis (3.5%). Sex was not associated with abnormal ocular findings (P>0.05). On the other hand, advanced age was a significant risk factor for ocular manifestations of COVID-19 (P<0.05). Only the abnormal ocular findings of the anterior segment were found to be associated with longer duration of hospital stay.

Conclusions
Elderly people were more likely to develop ocular manifestations of COVID-19 compared with their younger counterparts, irrespective of gender. A significant proportion of infected people developed ocular manifestations of COVID-19.
ĐÁNH GIÁ CỦA SINH VIÊN VỀ CÁC KẾT QUẢ ĐẠT ĐƯỢC TỪ TRẢI NGHIỆM HỌC TẬP TẠI TRƯỜNG ĐẠI HỌC CÔNG NGHIỆP THÀNH PHỐ HỒ CHÍ MINH
Authors: NGUYỄN THỊ THU TRANG  
Published: March 2022

Nghiên cứu được thực hiện nhằm tìm hiểu đánh giá của sinh viên về các kết quả họ đạt được từ trải nghiệm học tập tại trường Đại học Công nghiệp TP. HCM (IUH) cũng như mức độ hài lòng của sinh viên đối với trải nghiệm này. Khảo sát bằng bảng hỏi được sử dụng để thu thập dữ liệu. Thống kê mô tả được sử dụng để phân tích dữ liệu. Dữ liệu thu được từ trả lời của 497 sinh viên đang theo học tại Trường cho thấy: (i) sinh viên cho rằng trải nghiệm học tập tại trường có đóng góp nhiều vào sự phát triển nhân cách, nhưng chỉ đóng góp ở mức trung bình đối với sự tích lũy kiến thức, phát triển các kỹ năng học tập và sự chuẩn bị cho nghề nghiệp tương lai của họ; (ii) mức độ hài lòng của sinh viên đối với trải nghiệm học tập tại trường chưa cao. Về mặt lý luận, nghiên cứu đã bổ sung những khía cạnh còn ít được đề cập trong các nghiên cứu ở Việt Nam về kết quả đào tạo của giáo dục đại học ví dụ như sự đóng góp của các trường đại học đối với sự phát triển nhân cách của sinh viên và sự chuẩn bị nghề nghiệp cho sinh viên. Về mặt thực tiễn, nghiên cứu đã chỉ ra một số khía cạnh Nhà trường cần cải thiện để nâng cao chất lượng đào tạo của mình bao gồm việc chú trọng phát triển cho sinh viên tư duy phản biện, các kỹ năng viết, phân tích số liệu thống kê, giải quyết vấn đề cũng như việc tạo ra một môi trường học tập thân thiện hơn cho sinh viên.
COVİD-19 SÜRECİNDE ÜNİVERSİTE ÖĞRENCİLERİNİN ÖRGÜTSEL ADALET ALGILARININ UZAKTAN EĞİTİME KARŞI TUTUMLARI VE YENİLİKÇİ DAVRANIŞ EĞİLİMLERİ ÜZERİNE ETKİSİ: BİR ALAN ARAŞTIRMASI
Authors: ÖRÜCÜ Edip , HASIRCI Itır , KURT Pınar 
Published: March 2022

Amaç: Bu araştırmanın amacı Covid-19 sürecinde üniversite öğrencilerinin örgütsel adalet algılarının yenilikçi davranış ve uzaktan eğitime karşı tutumları üzerine etkisini araştırmaktır.
Yöntem: Araştırmanın evrenini, Bandırma Onyedi Eylül Üniversitesi’nde öğrenim gören 15.721 öğrenci oluşturmakta olup, örneklemini aynı üniversitede öğrenim görmekte olan 393 öğrenci oluşturmaktadır. Araştırmada veri toplama yöntemi olarak anket uygulaması gerçekleştirilmiştir. Anketlerden elde edilen verilerle frekans analizi, güvenilirlik analizi, normallik testi, korelasyon analizi ve regresyon analizi yapılmıştır.
Bulgular: Yapılan regresyon analizinin sonucuna göre örgütsel adalet algısının bir alt boyutu olan dağıtım adaletinin yenilikçi davranış eğilimleri üzerinde anlamlı bir etkisinin olduğu tespit edilirken, örgütsel adalet algısının diğer iki alt boyutu olan prosedür adaletinin ve etkileşim adaletinin yenilikçi davranış eğilimleri üzerinde anlamlı bir etkisi bulunamamıştır. Dağıtım adaleti ve prosedür adaletinin uzaktan eğitime karşı tutumları üzerinde anlamlı etkisinin olduğu tespit edilirken, etkileşimsel adaletin uzaktan eğitime karşı tutumları üzerinde anlamlı etkisinin olmadığı belirlenmiştir. Çalışmanın sonuç bölümünde elde edilen sonuçlar tartışılıp yorumlanmıştır.
Özgünlük: Araştırmanın konusu ile ilgili literatürde çok sayıda araştırmaya rastlanılmadığından bu çalışmanın alan yazına katkıda bulunması beklenmektedir.
Malaysian Civilian Nurses in Military Hospitals
Authors: Ismail Leena , Ishak Norimah , Othman Normah 
Published: March 2022

A job satisfaction study among civilian nurses was conducted in 3 Military Hospitals in Malaysia. A Participant convenient sample of n=172 was selected for statistical analysis and the response rate was 63.7 %. Responsibility, Staff Relation, Opportunity to Develop and Patient Care were domains identified that had high level of job satisfaction. Staff Relation domain was significant with the highest P- value among demographic data. The dataset was not distributed normally as the distribution was skewed left. The findings of the study revealed that there was significant positive relationship that showed general satisfaction among the domains. From the study it could be concluded that there was the influence of general satisfaction with all the reviewed elements. There was correlation with each other by 45% as indicated by the R2 value in the regression test.
O USO DO CANABIDIOL EM CRIANÇAS COM SÍNDROME DE DRAVET: UMA REVISÃO DE LITERATURA
Authors: Carvalho Gabriela Gimenes , Mardula Fernanda Paza , Gonçalves Maitê Montandon , Araujo Maria Carolina Cervi , Santos Maria Eduarda Hirata dos , Barros Gérsika Bitencourt Santos 
Published: March 2022

Introdução: A Síndrome de Dravet é uma encefalopatia epiléptica resistente à medicamentos e apresenta 3 fases, que levam a comprometimentos cognitivos e comportamentais. Devido à ineficácia dos remédios existentes e necessidade de novas medidas terapêuticas, surgiu o interesse pelo uso de canabidiol. Materiais e métodos: foram utilizadas as palavras chaves Dravet syndrome; Dravet; Dravet pharmacology; Dravet syndrome and cannabidiol; Cannabinoids epilepsy. Foram utilizadas as seguintes bases de dados: PubMed, Portal de periódicos da Capes e Google Acadêmico. Os critérios de inclusão dos artigos foram: artigos publicados em português e inglês entre 2011 e 2021 e com qualis mínimo B3 que foi consultado na Plataforma Sucupira. Foram excluídos artigos cujos objetivos de trabalho não se alinhavam aos interesses dessa pesquisa. Resultados: Dentre os 53 artigos selecionados para análise, apenas 22 foram utilizados como amostragem final da pesquisa. Dentre eles, 12 tratavam exclusivamente sobre a síndrome de Dravet e seus aspectos clínicos. Foi constatado, em 10 artigos, a relação entre a Síndrome de Dravet e o uso de canabidiol como tratamento para a mitigação das crises convulsivas. Além disso, os artigos também destacam outros aspectos relacionados a patologia, como outras opções de medicamentos. Conclusão: A utilização do princípio ativo CBD é eficaz para um dos principais sintomas da síndrome de Dravet, as crises convulsivas, e vem sendo cada vez mais estudado devido sua alta eficácia.
Root Barriers and Windthrow Potential
Authors: Smiley E. Thomas , Key Albert , Greco Craig 
Published: March 2022

AbstractThis study was developed to determine if commercially available ribbed barriers reduce or increase the stability of trees under severe lateral stress. Green ash (Fraxinus pennsylvanica) were planted in November 1996: 6 in surrounding-type tree root barriers and 6 without barriers. Half of each group was pulled over in July 1999 under dry (14% water) soil conditions and the other half was pulled over under saturated (33% water) soil conditions. The force required to pull the trees over was measured as was the wind resistance of the trees. Slightly more force was required to pull over the trees grown within root barriers than the control trees. The force required for the weakest tree, however, was far greater than that exerted by a 100-mph (160-kph) wind. The reason for the increased strength of the root barrier trees appeared to be the deeper root system.
Effects of Road Distance and Protective Measures on Deicing NaCl Deposition and Soil Solution Chemistry in Planted Median Strips
Authors: Pedersen Lars Bo , Randrup Thomas B. , Ingerslev Morten 
Published: March 2022

AbstractThe deposition pattern of deicing salt and the resulting concentrations in the soil water were determined in planted median strips of two major approach roads with speed restrictions of 70 kmh (43.5 mph) in Copenhagen, Denmark. The objectives were to evaluate the effect of distance from the roadside and to test different straw mat protective measures. Deposition and soil water concentrations of sodium chloride (NaCl) decreased significantly within 2 m (6.6 ft) from the roadside compared to areas farther away. Straw mats mounted like a skirt around the tree stem did not constitute a proper protection against salt spray or splash and high salt concentrations in the soil water. In contrast, protection with straw mats on all sides of the trees resulted in a small but measurable effect. The highest concentrations of NaCl in the soil water were seen during the winter. However, there was a strong tendency of elevated concentrations persisting throughout the subsequent summer, which suggests that serious salt stress exists on the trees during the growing season. We concluded that planting at a distance of more than 2 m from the roadside is more effective than using straw mats in reducing the undesirable effects of salt spray deposition on trees as well as the salt concentration in the soil water.
The Influence of Waterlogging on the Establishment of Four Australian Landscape Trees
Authors: Smith Karen D. , May Peter B. , Moore Gregory M. 
Published: March 2022

AbstractAn experiment was conducted to test the ability of recently planted trees to grow new roots under waterlogged conditions and to recover from waterlogging.Corymbia maculata(spotted gum, syn.Eucalyptus maculata), Lophostemon confertus(brush box),Platanus orientalis(oriental plane), andPlatanus=acerifolia(London plane) were subjected to a period of waterlogging and then to a recovery phase after waterlogging had ceased. Root length was measured at the end of both the waterlogging and recovery phases. The species were found to vary considerably in their ability to tolerate and recover from a period of waterlogging. Waterlogging suppressed root and shoot growth in all experimental species. Young spotted gum and oriental plane were able to initiate new roots under waterlogged conditions but London plane and brush box were not.
A Survey to Determine the Leaf Nitrogen Concentrations of 25 Landscape Tree Species
Authors: Perry Ed , Hickman Gary W. 
Published: March 2022

AbstractA survey was conducted to determine the concentrations of leaf nitrogen in 25 landscape tree species. Leaf samples were taken from mature, healthy trees in the landscape and analyzed for percent (total) nitrogen. Concentrations ranged from 1.0% (dry weight basis) for deodar cedar(Cedrus deodara)and Southern magnolia(Magnolia grandiflora)to 3.6% for white mulberry(Morus alba). The leaf nitrogen levels determined by the current study were compared to two other published surveys. From a practical standpoint, the list of tree species and their corresponding minimum leaf nitrogen values from visually healthy trees will allow arborists and landscape maintenance professionals to more effectively use leaf analysis for diagnosing nitrogen deficiency. The information can also be used for designing fertilizer programs, much as critical leaf nutrient level guides are currently used in the fruit and nut tree industries.
“Personality in prison uniform”. The influence
of personality on building work engagement,
applying job crafting strategies and well-being
among prison officers
Authors: Nowicka-Kostrzewska Justyna , Rożnowski Bohdan 
Published: March 2022

BackgroundNumerous studies have been devoted to analyzing the negative effects of occupational stress on the mental health of prison officers. Less attention is paid to positive mechanisms, as postulated by positive psychology. The aim of the study was to examine the relationship between personality traits and the strategies used by prison officers to build engagement, and professional well-being by adjusting the workplace to their strengths, skills and professional preferences.Participants and procedureTwo hundred eighty prison officers, aged 22 to 52, participated in the study (26% female). The following measurement tools were used: a personality scale (IPIP-BFM-20), the Job Crafting Questionnaire (PP), the Utrecht Work Engagement Scale (UWES-9) and the Workplace Well-being Questionnaire (KDMP).ResultsPersonality traits such as extraversion, conscientiousness and intellect determine the type of job crafting strategies used, specifically increasing structural resources and increasing challenges, while extraversion and conscientiousness were important for building work engagement, particularly dedication at work, and the levels of well-being at work. The influence of the variable intellect was also found to be significant.ConclusionsThe collected evidence indicates that there are organizational constraints to personality expression at work and its impact on key organizational behaviors and well-being at work. It also indicates the use of job crafting strategies to build work engagement.