bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatiotemporal variation of the water and sediment dynamics of the middle Yellow River Basin, China
Authors: Zhang Xiang , She Dongli , Ge Jiamin , Cao Taohong , Xia Yongqiu 
Published: December 2022

AbstractAfter decades of comprehensive management, the hydrology and sediment dynamics of the middle Yellow River Basin have changed significantly. However, the comprehensive evaluation of the water and sediment regimes and its potential attribution at the regional scale are limited. In this study, the hydrological characteristics and in‐reach sediment budget in the Coarse Sandy Hilly Catchments (CSHC) region and their potential attribution were investigated by using data from hydrological stations in the mainstream and tributaries and data from soil and water conservation measures (SWCMs) in different river reaches. The results indicated that the runoff and sediment load of the mainstream showed obvious spatial heterogeneity, both of which revealed a very significant decreasing trend from 1956 to 2018 (P < 0.01). The spatial heterogeneity of sediment load along the mainstream was more obvious than that of streamflow, and the Toudaoguai and Fugu stations had the largest difference in sediment transport trends. During the P1 period (1956‑1968), the streamflow of each reach was sufficient, and the riverbeds of the mainstream and channel on both banks were subject to serious scouring. In the P2‑P3 period (1969‑2018), in‐reach water decreased continuously, and the mainstream began to show a process from slight scouring to no scouring and even sediment deposition. Except for climate change being the main factor in streamflow reduction during the P2 period (1969‑1999) at the Fugu and Wubao stations, anthropogenic activities were the primary factors leading to the reduction in streamflow and sediment load in the CSHC region. Under the influence of the same measures, the sediment reduction rate in this region was greater than the runoff reduction rate. Furthermore, the SWCMs in different reaches indicated great diversity in the benefits of water and sediment reduction. Therefore, zoning regulation of the CSHC region should be carried out in the future, and the sustainable development of the regional vegetation ecosystem should be maintained.
Updated total IgE reference intervals in Norwegian adults
Authors: Vinnes Erik Wilhelm , Skarbø Birthe , Wentzel‐Larsen Tore , Sylte Marit S. , Apelseth Torunn Oveland 
Published: December 2022

AbstractBackgroundIt is important and expected of laboratories to provide updated reference intervals to the clinician. As no recent publications report adult total IgE reference intervals on a Scandinavian population, the aim of our study was therefore to provide an estimate on healthy Norweigian adults.MethodsA reference interval study was conducted in accordance to CLSI guidelines. Samples were collected from n = 252 presumably healthy adult participants enrolled through the regional blood donation program. Total IgE measurements were performed on the ImmunoCAPTM platform (Thermo Fisher Diagnostics) traceable to the WHO‐reference standard (75/502) for total IgE measurements.ResultsAn upper 95% total IgE reference limit was estimated to 302 kU/L (90% CI 177–388 kU/L), and the 97.5% percentile was estimated to 391 kU/L (90% CI 344–560 kU/L). No significant differences were found between participants who self‐reported having an allergic disease and participants who did not self‐report having an allergic disease.ConclusionOur results and other recent publications find markedly higher values than adult reference intervals established four decades ago which still remain widely used by clinical laboratories. We therefore recommend total IgE reference intervals should be critically reviewed and updated.
“There's more love between us”: The parental experience of attending Mellow Babies, a targeted, early intervention program for parents and their babies
Authors: Davidson Ciera , Raouna Aigli , Malcolm Ruaridh , Ibrahim Raquib , MacBeth Angus 
Published: December 2022

AbstractIt is recognized that parenthood in the context of psychosocial adversity can have negative implications for infant development. Parenting programs are the first line of intervention to improve outcomes for families; however, evidence for the effectiveness of group‐based, targeted early interventions is still scarce. Preliminary findings indicate Mellow Babies (MB) as a promising group‐based parenting program for families at risk for parenting difficulties. Using thematic analysis, we aimed to understand: (i) the aspects of the intervention that enabled parents to complete the program and (ii) the relational and behavioral changes perceived as valuable for parents and their babies post‐intervention. In total, 68 parents residing in the United Kingdom were interviewed after completing MB (49 mothers and 19 fathers; 88% self‐identified as British). Three themes and six subthemes were generated from the data. Parents identified several intervention components as beneficial, including the facilitators' interpersonal skills and multi‐dimensional, group‐based approach. Participant reflections highlighted three underlying mechanisms that enabled positive change: (i) the sense of community cultivated within the group, (ii) the process of formulating and re‐conceptualizing one's difficulties, and (iii) the opportunity to reshape interpersonal interactions. Findings are discussed within the context of perinatal and infant mental health.
An optical system for noninvasive microscopy of psoriatic mice in vivo
Authors: Lu Yiting , Zhu Yujie , Zhao Xiaohui , Pan Meng , He Hao 
Published: December 2022

AbstractPsoriasis is a chronic inflammatory skin disease involved with both complex morphological changes of skin and immune processes. The clinical diagnostics and research of psoriasis often require invasive biopsy which lacks their real‐time dynamics in vivo. Here we report a noninvasive microscopic system developed by combining in vivo fluorescent microscopy, optical clearing, and immunolabeling to enable real‐time imaging of immune cells and cytokines in blood flow in psoriatic animal models. The vascular morphology and time‐lapse kinetics of interleukin (IL)‐23, IL‐17, tumor necrosis factor‐α, and CD4+ cells in blood are captured at submicron resolution through the thickening epidermis and opaque scales during the development of psoriasis in vivo. Our data suggest IL‐23 recruits CD4+ cells to release IL‐17 in blood that further leaks out in the psoriatic skin area. This optical system enables noninvasive and real‐time assessment of immune molecules and cells in vivo, providing good potential for medical researches on psoriasis.
Complementary cycles of any length in regular bipartite tournaments
Authors: Bessy Stéphane , Thiebaut Jocelyn 
Published: December 2022

AbstractLet be a ‐regular bipartite tournament on vertices. We show that, for every with , has a cycle of length such that is Hamiltonian unless is isomorphic to the special digraph . This statement was conjectured by Zhang, Manoussakis and Song. In the same paper, the conjecture was proved for and more recently Bai, Li and He gave a proof for .
Forbidden subgraphs and 2‐factors in 3/2‐tough graphs
Authors: Sanka Masahiro 
Published: December 2022

AbstractA graph is ‐free if it has no induced subgraph isomorphic to , where is a graph. In this paper, we show that every ‐tough ‐free graph has a 2‐factor. The toughness condition of this result is sharp. Moreover, for any there exists a ‐tough ‐free graph without a 2‐factor. This implies that the graph is best possible for a forbidden subgraph in a sense.
Prevalence of undiagnosed HIV among children in South Africa, Côte d'Ivoire and Zimbabwe: a model‐based analysis to inform paediatric HIV screening programmes
Authors: McCann Nicole C. , Stanic Tijana , Penazzato Martina , Flanagan Clare F. , Abrams Elaine J. , Dugdale Caitlin M. , Johnson Leigh F. , Neilan Anne M. , Davies Mary‐Ann , Freedberg Kenneth A. , Fassinou Patricia , Doherty Meg , Essajee Shaffiq , Mushavi Angela , Soeteman Djøra I. , Ciaranello Andrea L. 
Published: December 2022

AbstractIntroductionTo improve the diagnosis and survival of children living with HIV (CLWH), the World Health Organization recommends testing approaches beyond traditional infant HIV testing programmes. Information about undiagnosed HIV prevalence among children of varying ages in the general population is needed to guide innovative national/subnational case‐finding and testing approaches.MethodsWe used the Cost‐Effectiveness of Preventing AIDS Complications (CEPAC)‐Pediatric model to estimate the prevalence of undiagnosed HIV in 2‐, 5‐ and 10‐year‐old children in South Africa, Côte d'Ivoire and Zimbabwe in 2018. We simulated cohorts of children born in 2008 (10‐year‐olds), 2013 (5‐year‐olds) and 2016 (2‐year‐olds). Country‐/year‐specific inputs for pregnant/breastfeeding women included: HIV prevalence (4.2–32.3%), HIV incidence (0.03–0.24%/month), knowledge of HIV status (27–89%) and antiretroviral drug coverage (36–95%). Paediatric inputs included early infant testing coverage (6–95%) and breastfeeding duration (0–20 months). We projected the proportion of surviving CLWH in whom HIV remained undiagnosed and the undiagnosed HIV prevalence among surviving children of each age in the general population. For children born in 2016, we projected survival and diagnosis of all CLWH through 2026. We conducted sensitivity analyses on model parameters.ResultsIn 2018, the projected proportion of surviving CLWH whose HIV remained undiagnosed in South Africa/Côte d'Ivoire/Zimbabwe was 44.2%/55.8%/52.9% among 2‐year‐old CLWH; 29.0%/37.8%/33.2% among 5‐year‐old CLWH; and 18.3%/25.4%/23.1% among 10‐year‐old CLWH. Projected general population undiagnosed HIV prevalence in South Africa/Côte d'Ivoire/Zimbabwe was 0.44%/0.32%/0.68% among 2‐year‐olds; 0.25%/0.17%/0.41% among 5‐year‐olds; and 0.24%/0.14%/0.38% among 10‐year‐olds. Among all CLWH born in 2016, 50–54% were projected to die without HIV diagnosis (and subsequently without treatment) within 10 years after birth; 80–85% of these deaths occurred in the first 2 years.ConclusionsProjected population‐level undiagnosed HIV prevalence is low and sharply decreases after age 2, with more CLWH dying than being diagnosed. Despite low undiagnosed prevalence in the general population of older children, we project that a large proportion of CLWH remain undiagnosed, suggesting that innovative strategies targeting untested children of all ages outside of health facility settings should be prioritized. Programmes could consider routine testing of the general population of children below 2 in all settings and children of all ages in high‐prevalence settings.
In silico study of SARS‐CoV‐2 spike protein RBD and human ACE‐2 affinity dynamics across variants and Omicron subvariants
Authors: Abeywardhana Shamali , Premathilaka Malinda , Bandaranayake Upeka , Perera Deshan , Peiris L. Dinithi C. 
Published: December 2022

AbstractThe coronavirus disease 2019 virus outbreak continues worldwide, with many variants emerging, some of which are considered variants of concern (VOCs). The WHO designated Omicron as a VOC and assigned it under variant B.1.1.529. Here, we used computational studies to examine the VOCs, including Omicron subvariants, and one variant of interest. Here we found that the binding affinity of human receptor angiotensin‐converting enzyme 2 (hACE2) and receptor‐binding domain (RBDs) increased in the order of wild type (Wuhan‐strain) < Beta < Alpha < OmicronBA.5 < Gamma < Delta < Omicron BA.2.75 < BA.1 < BA.3 < BA.2. Interactions between docked complexes revealed that the RBD residue positions like 452, 478, 493, 498, 501, and 505 are crucial in creating strong interactions with hACE2. Omicron BA.2 shows the highest binding capacity to the hACE2 receptor among all the mutant complexes. The BA.5's L452R, F486V, and T478K mutation significantly impact the interaction network in the BA.5 RBD‐hACE2 interface. Here for the first time, we report the His505, an active residue on the RBD forming a salt bridge in the BA.2, leading to increased mutation stability. When the active RBD residues are mutated, binding affinity and intermolecular interactions increase across all mutant complexes. By examining the differences in different variants, this study may provide a solid foundation for structure‐based drug design for newly emerging variants.
Lime requirement for agricultural soils: A review of the current and potential methods for routine use
Authors: Nguyen Tho 
Published: December 2022

AbstractLiming is one of the key agronomic practices to improve crop yields in acid soils because, among other things, it reduces aluminum toxicity and creates favorable conditions for crop growth. For an effective liming program, the methods to determine lime requirement should be as precise as possible. This paper reviews the existing lime requirement methods and discusses the potential of a new one suitable for routine use in the laboratory to test most agricultural soils. The most widely used lime requirement methods can be categorized into four groups: titration, incubation, buffer, and field methods. Other methods such as spectroscopy method or the use of empirical equations have also been adopted. Although some methods are highly reliable, they are not optimal for routine use because they are inconvenient during the laboratory procedures or cannot be validated for all conditions. Based on the linearity between soil pH and the added base in the pH range from 4.5–6.5 in most agricultural soils, a titration‐based method on 1:1 soil:0.01 M CaCl2 slurry of a single sample appears to be a promising candidate for routine use. In further studies, this generally applicable method should be evaluated to provide a better comparison to established methods for lime requirement determination.
Effective burn‐in reduction of organic light‐emitting diode display using perceptual color difference between logo and background
Authors: Kim Chang‐Jae , Seok In‐Hoo , Lee Ji Won , Kim Moon‐Cheol 
Published: December 2022

AbstractThe paper proposes a method to delay the burn‐in effect of an organic light‐emitting diode (OLED) display. Usually, the burn‐in occurs in broadcasting company logo regions. In previous studies, logos were compensated by reducing the logo luminance by a specific ratio. This paper proposes a novel logo‐compensation method regarding the perceptual color difference between a logo and background areas. The proposed method has the advantage of being less affected by changes in the surrounding area than the existing compensation method, minimizing the deterioration of the recognition of the logo, and delaying the burn‐in as much as possible.
ZNF655 mediated by LINC01210/miR‐124‐3p axis promotes the progression of gastric cancer
Authors: Bo Wei , Wang Xu‐Guang , Zhang Min , Zhang Zhong 
Published: December 2022

AbstractGastric cancer (GC) is a common malignant tumor that usually originates from the epithelium of the gastric mucosa. ZNF655 was a suppressor gene of many cancers. However, the mechanism of ZNF655 in GC remains unknown. Quantitative polymerase chain reaction was used to assess the expression of ZNF655, LINC01210, and miR‐124‐3p. Western blotting was used to monitor ZNF655 protein expression. MTT, clone formation, transwell, and flow cytometry were all used to investigate the functions of GC cells. The interactions between ZNF655, LINC01210, and miR‐124‐3p were confirmed using the dual‐luciferase reporter gene assay and the RIP assay. ZNF655 was highly expressed in GC cells. ZNF655 knockdown reduced GC cell viability, proliferation, migration, invasion, and induced apoptosis. The level of miR‐124‐3p was significantly reduced in GC cells. Besides, miR‐124‐3p targeted ZNF655 and inhibited its expression. MiR‐124‐3p mimics inhibited GC cell progression, but ZNF655 overexpression reversed these effects. Moreover, LINC01210 was found to be highly expressed in GC cells and to be able to sponge miR‐124‐3p. Furthermore, inhibiting miR‐124‐3p or increasing ZNF655 could counteract the effects of LINC01210 knockdown on GC cell development. Finally, ZNF655 promoted GC cell progression and was regulated by the LINC01210/miR‐124‐3p axis.
Generalized Killing Ricci tensor for real hypersurfaces in the complex quadric
Authors: Suh Young Jin 
Published: December 2022

AbstractFirst we introduce a new notion of generalized Killing Ricci tensor which is equivalent to the notion of cyclic parallel Ricci tensor for real hypersurfaces in the complex quadric . Next, in terms of ‐principal or ‐isotropic unit normal vector fields we give a complete classification of real hypersurfaces in with cyclic parallel Ricci tensor.
Polyacrylonitrile‐based electrospun nanofibers – A critical review
Authors: Aslam M. , Khan T. , Basit M. , Masood R. , Raza Z.A. 
Published: December 2022

AbstractThis review is based on the fundamental aspects and applications of polyacrylonitrile (PAN)‐based electrospun composite nanofibers. Various electrospinning techniques have been discussed here. polyacrylonitrile is an acrylic polymer of commercial significance that has superior thermal, mechanical, electrical, and chemical properties. The integration of polyacrylonitrile nanofibers with nanoparticles including carbon nanotubes, graphene nanosheets, graphene oxide, metal oxides, and their combinations has greatly improved the physicochemical properties of the polyacrylonitrile electrospun nanofibers. The enhanced features of polyacrylonitrile nanofibers have resulted from interfacial bonding of nitrile groups with the nanofiller used, chemical compositions, hydrophobicity, porosity, and wettability of these nanofibers. This article fundamentally features a few key possibilities of polyacrylonitrile‐based electrospun composite nanofibers and their applications. A special focus has been made on polyacrylonitrile‐based inorganic nanoparticles, graphene nanosheets, graphene oxide, and carbon nanotubes embedded electrospun nanofibers, for their potential applications in supercapacitors, high power batteries, filtration membranes, electromagnetic interference shielding, and strain sensors. Achieving low cost, high selectivity, excellent recyclability, and high absorption capability are the major challenges for electrospun nanofiber fabrications. These electrospun nanofibers require extensive research in the future to advance the technologies to bring them to the commercial market.
Machine learning based multi‐label classification of single or mixed‐composition urinary stones in in vivo spectral CT
Authors: Li Xian , Tang Peng , Liang Fangrong , Wang Linjing , Huang Xiaoyan , Li Jieer , Zhen Xin 
Published: December 2022

AbstractBackgroundUrinary stones comprise both single and mixed compositions. Knowledge of the stone composition helps the urologists choose appropriate medical interventions for patients. The parameters from the spectral computerized tomography (CT) analysis have potential values for identification of the urinary stone compositions.PurposeThe present study aims to identify the compositions of urinary stones in vivo using parameters from spectral CT and machine learning, based on multi‐label classification modeling.MethodsThis retrospective study collected 252 urinary stone samples with single/mixed compositions (including carbapatite [CP], calcium oxalate monohydrate [COM], calcium oxalate dehydrate [COD], uric acid [UA], and struvite [STR]), which were confirmed by ex vivo infrared spectroscopy. Parameters were extracted from an energy spectrum analysis (ESA) of the spectral CT, including the effective atomic number (Zeff), Zeff histogram, CT values at a given x‐ray energy level, and material densities. These ESA parameters were utilized for composition analysis via a multi‐label classification fusion framework, where 250 multi‐label models were built and the classification decisions from the top performance models were integrated by a multi‐criterion weighted fusion (MCWF) approach in order to reach a consensus prediction. An example‐based metric and label‐based metric were used for global and label‐wise accuracy evaluations, respectively. The top‐ranked parameters associated with discriminating the stone composition were also identified.ResultsThe multi‐label classification fusion framework achieved an overall of 81.2%, with of 86.7% (CP), 90.6% (COM), 80.6% (COD), 95.0% (UA), and 94.4% (STR) for each composition on the independent testing cohort 1, and of 76.4% with of 80.5% (CP), 88.7% (COM), 74.9% (COD), 94.4% (UA), and 98.5% (STR) on the independent testing cohort 2.ConclusionThe parameters extracted from the ESA on spectral CT can be utilized to characterize single or mixed stone compositions via multi‐label classification modeling. The generalization capability of the proposed methodology still requires further verification.
Bounding surface rotational hardening model for overconsolidated clay accounting for evolving fabric anisotropy
Authors: Yu Yang , Yang Zhongxuan 
Published: December 2022

AbstractSoil is inherently anisotropic owing to the sedimentation process under gravity and is generally under anisotropic stress state in the field. To reflect the influence of anisotropic consolidation, rotational hardening (RH) is favorably used in constitutive models, mimicking in‐situ stress conditions. However, most of the existing models do not account for the inherent anisotropy of clays under isotropic stress state as well as the interplay between the fabric and loading direction, and the corresponding initial yield surface is assumed to be oriented along the hydrostatic axis. Furthermore, as the rotational angle is usually deemed as the clayed soil's anisotropy measure, a critical yield surface without rotation appears to contradict the highly anisotropic fabric at critical state. In this study, an anisotropic bounding surface model that incorporates RH and fabric anisotropy is formulated to simulate the behavior of overconsolidated (OC) clay subject to different consolidation histories, while addressing the aforementioned inconsistency issue. During the loading process, both fabric anisotropy and rotational angle evolve continuously based on their respective evolution rules. Fabric anisotropy evolves to the critical state when the rotational angle returns to zero, satisfying the anisotropic critical state theory (ACST). In addition, the model employs an anisotropic elasticity to consider the influence of the initial fabric at a low‐stress level. The predictive capacity of the model can be demonstrated by simulating several compression and extension tests on clay over a wide range of overconsolidation ratios (OCRs) and anisotropic consolidation stress ratios under both drained and undrained conditions.
Online social network fundraising: Threats and potentialities
Authors: Wymer Walter , Čačija Ljiljana Najev 
Published: December 2022

AbstractThere has been a growth in online fundraising from crowdfunding apps, like GoFundMe, that propagate fundraising appeals on social networking sites. In the online space, these crowdfunding apps pose a potential threat to the traditional intermediation role of charities. The disintermediation threat is that donors choose crowdfunding intermediaries instead of charities to channel their giving. In this article, we discuss what makes crowdsourced fundraising effective and how charities can adapt to this new dynamic for more effective online fundraising emphasizing two key success factors: brand strength/reputation and managing the donor experience. In addition, we explain the advantages and disadvantages of social media fundraising and giving and propose ways charities can leverage their good reputations and public trust to stimulate reintermediation. Finally, we propose a landscape for future research based on model that emphases the fundraising campaign's ability to stimulate viral sharing within and between online social networks.