bluuebunny/crossref_metadata_2025_split huggingface dataset:
Setting up of an Integrative Center for the Management of Mild-moderate COVID-19
Authors: Nesari Tanuja Manoj , Dharmarajan Prasanth , Mahapatra Arun Kumar , Rajagopala S , Nesari Manoj , Kapoor Alka , Bhati Deepak , Kumar Anil , Kumari Sonam , Arshathjyothi P S , Dileep Aparna 
Published: June 2022

Introduction:
Besides the expansion of vaccine drive, the discovery of new strains of corona virus is creating havoc all around the world. Based on the pragmatic trial conducted, there is an increasing recognition that an effective integrated holistic approach is urgently needed to combat the COVID pandemic. During an infectious outbreak, a health-care unit is anticipated to function as a high-level isolation unit. Herein, we describe the execution plan, experiences, observations, and challenges that were encountered during the establishment and functioning of COVID Health-Care Ward at All India Institute of Ayurveda.

Methodology:
Since the situation was novel, standard operative procedures and protocols were developed accordingly. Strategic plans carried out in infrastructure, biomedical waste management, surveillance, and observations were compiled directly from the hospital administration.

Results:
Till date when the 29th team has completed the duty rotation, about 600 COVID mild-to-moderate positive cases have been successfully managed. Zero incidence of nosocomial COVID transmission or death has been reported so far. The recovery speed of patients was found to be remarkably faster at COVID Health Center-AIIA as compared to all other hospitals of the state and a significant number of patients were recovered with the use of Ayurvedic medications alone. On follow-up, only a limited number of patients (two patients) turned up with mild severity of post-COVID complications. Mild respiratory discomfort was noted in these patients for a period of 2 months. The score for Anxiety Depression Scale of among patients and health-care workers reduced significantly.

Conclusion:
Indigenous system of medicines is comparatively less explored in pandemic times. Here, a tertiary care hospital has upgraded to integrative health-care model in the management of mild-to-moderate COVID-19 cases.
Comparison of performance of undergraduate medical students trained in conventional and integrated curriculums
Authors: Abbas Seyyedha , Sadiq Naushaba , Zehra Tabassum , Ullah Ihsan , Adeeb Humera 
Published: June 2022

Introduction:
Foundation University Medical College is one of the few institutions in Pakistan that have developed an Integrated Modular Teaching Program. This mode of teaching is a novel addition to our conventional system and needs evaluation. The objective of this study was to compare the overall cumulative results of undergraduates from (Group A/2015) conventional (old) with (Group B/2016) integrated (new curriculum) final professional examinations and to correlate the overall cumulative results of final professional examinations with their admission test results.

Materials And Methods:
We compared the final professional examination results of Group A and Group B undergraduates. Both the groups had identical final examinations in terms of pattern, subjects, examiners, and duration. In addition, a measure of central tendency and standard deviation was calculated and made comparisons between entry and final professional examination results. Finally, the t-test was used to compare the theoretical and practical scores. In addition, it established the reliability and validity of the results.

Results:
The overall performance of undergraduates who trained on integrated curriculum (97.0%) was better than that of undergraduates who had trained on conventional curriculum (85.2%). Comparison between the various components of the professional examinations using the ANOVA test also revealed that the same group of undergraduates performed better with P < 0.05, which is 0.002, which showed significant results. Cronbach's alpha for overall performance was 0.957, whereas for the theoretical and practical examinations, it was 0.792 and 0.897, respectively.

Conclusion:
The results revealed that the undergraduates who had trained on integrated curriculum had improved performance in the final professional examinations both in theory and practical.

The following core competencies are addressed in this article:
Medical Knowledge, Practice-based learning and improvement, Systems-based practice, and Interpersonal and communication skills.
The proportion of hand and knee osteoarthritis and its associated risk factors among an urban diabetic population
Authors: Pathak Barsha Gadapani , Rahini S , Manapurath Rukman Mecca 
Published: June 2022

Introduction:
Osteoarthritis (OA) is found to be a leading cause of disability in people with diabetes mellitus (DM). This study aimed to find the proportion of knee OA and hand OA and its risk determinants among people with DM.

Materials and Methods:
A cross-sectional study was conducted among 258 diabetic subjects attending the general outpatient department of a tertiary care hospital over 4 months. A predesigned case record form was used to collect details on sociodemographic profiles and various factors related to OA. The American College of Rheumatology criteria were used for the diagnosis of both knee and hand OA. Data analysis was done using the SPSS version 16. Chi-square/Fisher's exact test was used wherever applicable to find the association of various factors with OA.

Results:
The overall proportion of OA in diabetic subjects was 48.4%. The proportion of only hand OA was 25.2%, only knee OA was 14.3%, and both hand OA and knee OA were 8.9%. Age, female sex, duration of DM, irregularity in taking diabetic medications, hypertension, menopause, and body mass index were found to be significantly associated with both hand and knee OA. Physical inactivity and previous joint injury were found to be associated with knee OA. An inverse association with alcohol consumption was found. On logistic regression, we found irregularity in taking diabetic medication to be a significant risk factor for hand and knee OA. The duration of DM and taking alternate medications for DM were also found to be significant risk factors for hand OA. Prior knee injury is a significant risk factor for knee OA.

Conclusion:
There exists an association between OA and DM, and this suggests the need for early diagnosis, good disease management, and medication adherence and to implement preventive strategies so as to prevent further disabilities and improve quality of life.

The following core competencies are addressed in this article:
Patient care and procedural skills, Medical knowledge, Systems-based practice, Practice-based learning and improvement.
Development and training of mental health professionals in providing psychological intervention and support for women survivors of intimate partner violence – A pre–post evaluation study
Authors: Vranda Mysore Narasimha , Kumar Channaveerachari Naveen , Janardhana Navaneetham 
Published: June 2022

ABSTRACT

Context:
Health care providers play a significant role as they are the first contact for seeking help for intimate partner violence (IPV) survivors.

Aims:
This research aimed toward developing a comprehensive culturally appropriate intervention package for the mental health professionals (MHPs) to provide psychological intervention and support for women survivors of IPV and test the training impact on the level of attitude, knowledge, and preparedness to respond to IPV disclosure among MHPs.

Settings and Design:
A single group, pre–post intervention study, was conducted at Tertiary Mental Health Hospital in the Southern part of India, Bengaluru.

Materials and Methods:
A total of 30 MHPs were recruited for the study using purposive sampling. MHP Attitude, Knowledge, Preparedness to Manage IPV (MAP–IPV) questionnaire was used to collect the data.

Statistical Analysis Used:
Descriptive statistics were used to assess the sociodemographic characteristics of the participants. The pre–post evaluation was analyzed using the independent “t” test by comparing the means scores of the MAP–IPV questionnaire. The data were analyzed using the Statistical Package for the Social Sciences (SPSS) – 20 version of the software.

Results:
The results revealed a lack of attitude, knowledge preparedness, and available resources materials among MHPs in addressing IPV cases. Pre–post evaluation showed statistically significant improvement in attitude, knowledge, and preparedness to identify and respond to IPV disclosure among MHPs after the intervention program.

Conclusion:
The comprehensive IPV intervention package effectively brings gain in attitude, knowledge, and preparedness among MHPs in addressing survivors of IPV. Practice guidelines and clear referral pathways following IPV disclosure need to be implemented to support the gains made through the training.
Quantitative and Qualitative Palatal Rugae Pattern Analysis in Population of Punjab
Authors: Behl Ashima B. , Vinod VC , Kaur Jaswinder , Vohra Puneeta , Kaur Sumit , Bali Vikram 
Published: June 2022

Background:
Palatal rugae are irregular, asymmetric ridges of mucous membrane extending laterally from incisive papillae and anterior part of palatal raphe. Palatal rugae patterns are unique to individuals.

Aim and Objectives:
The aim of the study was to identify a pattern of palatal rugae in terms of size, shape, number, and to compare rugae patterns in males and females of Punjab population.

Material and Methods:
A total of 420 diagnostic maxillary casts (210 men and 210 women) were randomly collected from various dental clinics and were subjected to visualization using graphite pencil and magnifying glass under adequate light. Student t test using SPSS software version 20 was utilized for statistical analysis.

Results:
Total of 3,465 rugae were observed. Out of the total rugae examined, primary type of rugae were found to be more followed by secondary and fragmentary/tertiary. On the basis of shape, it was found to be straight followed by wavy, curved, and circular. On the basis of modified Kapali classification, converging type of rugae were found to be more in men and diverging type were found to be more in women. The mean rugae were found to be more in women than men. Statistically significant values were observed in relation to size (secondary type), and shape (curved and circular).

Conclusion:
The present study was localized to the population of Punjab. Not many studies with such a large sample size have been done for this region. Palatal rugae pattern is definitely a sufficient characteristic to discriminate between genders.
Analysis Report of Adherence to Consort Statement for Reporting Randomized Controlled Trials (RCTs) Associated with Temporomandibular Disorders (TMDs)
Authors: Shete-Motgi Anagha , Shete Mrinal , Bhate Kalyani , Kshirsagar Kapil , Kakodkar Pradnya 
Published: June 2022

Purpose:
Temporomandibular disorders (TMDs) and their management are widely sought after by clinicians. They often refer to the reported randomized controlled trials (RCTs) in the literature. The Consolidated Standards of Reporting Trials (CONSORT) statement aims to improve the quality of published RCTs and is endorsed by healthcare journals. Despite the widespread acceptance of CONSORT, its use for reporting clinical trials in the journals remains suboptimal. The purpose of this study was to evaluate, to what extent RCTs related to TMDs have adhered to the CONSORT statement.

Methodology:
RCTs related to TMDs, published in PubMed from January 2017 to March 2021 were retrieved. Each article was assessed for its adherence to the CONSORT statement by four trained and calibrated investigators.

Results:
88 articles were evaluated. Out of 37 items in the checklist, only 4 items demonstrated 100% adherence (item 2a, 2b, 5, 12a, and 16). The most under-reported items were 7a, 8b, 9, 10, 17a, 17b, 19, 23, and 24 (less than 50%). The mean percentage of adherence remained 71.2 ± 12.6. Only one study showed 100% adherence and three studies had less than 50% adherence. Considering adherence of abstract checklist, three items demonstrated 100% adherence (items 4, 5, and 6). Poor reporting was noted with items 8, 13, 15, and 16. The mean percentage of adherence to abstract reporting remained 68.60 ± 11.79.

Conclusion:
The present study indicates good adherence to CONSORT statement in reporting RCTs related to TMD management. Probably the mandatory instructions from the journals and increasing awareness among the researchers about CONSORT reporting might have done the trick.
The patient with obesity and super-super obesity
Authors: Kaye Alan D. , Lingle Brock D. , Brothers Jordan C. , Rodriguez Jessica R. , Morris Anna G. , Greeson Evan M. , Cornett Elyse M. 
Published: June 2022

ABSTRACT
Obesity is associated with increased morbidity and mortality related to many complex physiologic changes and the rise worldwide has had far ranging implications in healthcare. According to the World Health Organization, over 2.8 million people die each year from being overweight or obese. Patients who are obese often need surgical procedures or interventional pain procedures and are at higher risk of complications. Patients with super-super obesity are those with body mass index greater than 60 kg/m2 and are at even greater risk for complications. The present investigation reviews epidemiology, pathophysiology, and anesthesia considerations for best practice strategies in managing these higher risk patients. Clinical anesthesiologists must utilize careful assessment and consultation in developing safe anesthesia plans. Improvements in technology have advanced safety with regard to airway management with advanced airway devices and in regional anesthesia with ultrasound-guided nerve blocks that can provide increased flexibility in formulating a safe anesthetic plan. As well, newer drugs and monitors have been developed for perioperative use to enhance safety in patients with obesity.
Riesgos asociados con el trabajo y sus efectos en la salud, responsabilidad social empresarial. Ordenamiento jurídico Mexicano.
Authors: Almada Quintero María , Medina Wahnnatah Armando , Reyes Robles Marina , López Esquerra Luis , Medina Almada María , Medina Almada Ana 
Published: June 2022

El presente trabajo consiste en una revisión teórica sobre los riesgos asociados a la actividad laboral y sus efectos en la salud de los trabajadores, llevando a cabo una selección y análisis de trabajos o estudios realizados que guardan relación con el tema de este trabajo y que sirven como punto de referencia. Hoy en día las personas que laboran en escenarios productivos convierten a la empresa en un segundo hogar, pues ahí es donde se pasa la mayor parte de su tiempo. Actualmente es habitual encontrar que un trabajador, realice tareas ajenas a su puesto, así como también, con frecuencia se le pide realizar actividades fuera del horario establecido. En este sentido, cuando las exigencias son excesivas, la sobrecarga de trabajo puede repercutir en graves problemas, atentando la integridad física y salud del trabajador. Considerando estas situaciones como parte de la responsabilidad social de las organizaciones y su relación con las disposiciones del marco normativo en materia de riesgos laborales en México.
LINGUISTAS ESTRUTURALISTAS:
Authors: Benicio de Andrade Dias Juliana , Pereira de Carvalho Gleyce , Gonçalves de Andrade Moreira Raissa , Lopez Estivalet Gustavo 
Published: June 2022

O presente trabalho apresenta uma relação de linguistas importantes para o estruturalismo. Ao estudarmos essa teoria, percebemos que os mesmos autores são permanentemente citados, como Saussure e Bloomfield. Contudo, ao investigarmos de forma direcionada os linguistas que contribuíram para o desenvolvimento do estruturalismo, percebemos que diversos outros nomes complementam os estudos linguísticos para o desenvolvimento desta abordagem. Portanto, nosso objetivo principal foi apresentar um compilado dos principais autores estruturalistas e, como objetivos específicos, nosso trabalho pretendeu i) organizar cronologicamente os linguistas estruturalistas, ii) apresentar brevemente suas biografias, iii) pontuar suas principais contribuições para a linguística e iv) introduzir autores estruturalistas pouco (re)conhecidos. Dito isso, a metodologia deste trabalho está organizada em quatro etapas: pesquisa prévia dos autores, organização por local de trabalho, cronologia de publicação e discussão sobre suas contribuições. Como resultados, obtivemos uma lista com 25 linguistas estruturalistas, suas biografias e principais contribuições para a linguística.
Actividad Antioxidante, Antibacteriana y Citostática de Extractos de Cúrcuma (Curcuma Longa)
Authors: Omonte Rodriguez Liz Adriana 
Published: June 2022

Parte de la Industria Farmacéutica se desarrolla sobre la base de nuevas plantas descubiertas por los pueblos indígenas, la Cúrcuma, lo utilizaban de manera tradicional para el tratamiento de afecciones cutáneas, hepáticas, digestivas, cancerígenas, infecciones parasitarias, virales, bacterianas, entre otras. Objetivos:evaluar la actividad antioxidante, antibacteriana, tóxica, citostática y determinar la composición fitoquímica de extractos de Curcuma longa cultivada en el sector de Cristal Mayu del Chapare. Métodos:se prepararon dos extractos etanólicos 70% y 96%, se cuantificó los polifenoles por el método de Folin-ciocalteu, se evaluó la actividad antioxidante con el reactivo DPPH, se evaluó la actividad antibacteriana con dos bacterias gram negativas (E. coli y K. pneumoniae) y una bacteria gram positiva (S. aureus), se determinó la toxicidad sobre la Artemia salina y la actividad citostática mediante el ensayo de inhibición del crecimiento de la raíz de lechuga. Se cuantificó el total de curcuminoides. Resultados:el extracto al 96% presenta mayor cantidad de fenoles totales y posee actividad antioxidante. Solo el extracto al 96% presenta actividad antibacteriana frente a S. aureus, E. coli, K. pneumopniae. Por otro lado, la Cúrcuma presenta toxicidad frente a la Artemia salina, inhibe el crecimiento de la raíz de lechuga y posee un 5% de curcuminoides totales. Conclusiones:la caracterización de los compuestos confirma su composición como polifenoles, lo cual se relaciona a la actividad biológica de éstos, encontrándose que la Cúrcuma posee actividades antioxidantes, antibacterianas, citotóxicas y su importancia en el área de la salud como una alternativa para el tratamiento de muchas enfermedades.
Aplicación Intralesional de Antimoniales en el Tratamiento de Leishmaniasis Cutánea
Authors: Rojas Cabrera Ernesto 
Published: June 2022

Objetivo: evaluar la eficacia clínica de la aplicación intralesional de 3 versus, 6 inyecciones de Glucantime®, durante una o dos semanas en pacientes con leishmaniasis cutánea.
Métodos: estudio de tipo cuasi experimental. Se incluyó a 41 pacientes con leishmaniasis cutánea del área endémica tropical de Cochabamba, Bolivia. Los pacientes, fueron distribuidos aleatoriamente para recibir tratamiento intralesional con Glucantime®, en tres o seis aplicaciones. Todos ellos firmaron un consentimiento escrito de aceptación voluntaria de participar del estudio, que cuenta con el aval del comité de ética de la facultad de medicina UMSS.
Resultados: la evaluación realizada a la eficacia clínica, del empleo de tres o seis aplicaciones intralesionales de Glucantime® no encontró diferencias estadísticamente significativas entre ambas. Así mismo, tampoco se encontró diferencias significativas en cuanto a la cicatrización completa alcanzada al primer mes post tratamiento por ambos esquemas de aplicación.
Conclusiones: la cicatrización de las úlceras observada en este estudio, se consiguió independiente del esquema de tres o seis aplicaciones intralesionales de Glucantime® y estos resultados son comparables al tratamiento sistémico. Se considera que tres aplicaciones de Glucantime® intralesional es el límite mínimo como tratamiento para leishmaniasis cutánea con una sola úlcera cuyo tamaño sea menor a tres por tres centímetros.
SỰ CẢI THIỆN VĂN HÓA AN TOÀN NGƯỜI BỆNH TẠI BỆNH VIỆN QUẬN 4 SAU 4 THÁNG CAN THIỆP
Authors: Thị Lệ Hằng Nguyễn , Thanh Hiệp Nguyễn , Quỳnh Trúc Nguyễn 
Published: June 2022

Đặt vấn đề. Văn hóa an toàn người bệnh là phần rất quan trọng trong việc nâng cao chất lượng chăm sóc sức khỏe, đóng vai trò là nền tảng của an toàn người bệnh, làm giảm sai sót y khoa. Bệnh viện Quận 4 thu hút một lượng lớn bệnh nhân đến khám và chữa bệnh, góp phần giải quyết gánh nặng quá tải cho các bệnh viện tuyến cuối. Tuy nhiên, theo dữ liệu về tỷ lệ báo cáo sự cố, sai sót y khoa tại Bệnh viện Quận 4 trong những năm gần đây chưa cao, thấp hơn so với các báo cáo trong nước và quốc tế, và có những sự cố được phát hiện không phải do báo cáo. Phương pháp nghiên cứu. Nghiên cứu đánh giá can thiệp trước sau từ tháng 01/2021 -12/2021. Lấy mẫu toàn bộ nhân viên y tế đang làm việc ở 18 khoa/phòng tại Bệnh viện Quận 4. Chương trình can thiệp về lĩnh vực tần suất báo cáo sự cố trên 5 nội dung: Đánh giá, so sánh sự thay đổi Văn hoá an toàn người bệnh sau và trước chương trình can thiệp. Kết quả. Có 290 đối tượng tham gia trước can thiệp và 253 đối tượng tham gia sau can thiệp. Có sự khác biệt về điểm văn hóa trung bình trước và sau can thiệp có ý nghĩa thống kê ở các lĩnh vực sau: Lãnh đạo khoa khuyến khích An toàn người bệnh, Nhận thức về An toàn người bệnh, Thông tin phản hồi sai sót, Bàn giao và chuyển bệnh, Không trừng phạt khi có sự cố. Điểm văn hóa an toàn người bệnh trung bình tại bệnh viện sau can thiệp cao hơn trước can thiệp có ý nghĩa thống kê (p<0,001). Kết luận. Điểm văn hóa an toàn người bệnh sau can thiệp cao hơn trước can thiệp. Bệnh viện nên cập nhật thay đổi lại quy trình báo cáo sự cố và khuyến khích nhân viên y tế chủ động báo cáo. Nâng cao vai trò của tổ Quản lý chất lượng bệnh viện trong việc thông tin phản hồi sai sót. Có kế hoạch đào tạo và thu hút nguồn nhân sự về làm việc tại bệnh viện, giảm áp lực cho nhân viên y tế.
KẾT QUẢ GẦN CẮT GAN DO UNG THƯ BIỂU MÔ TẾ BÀO GAN
Authors: Mạnh Hùng Trần , Quế Sơn Trần 
Published: June 2022

Mục tiêu: mô tả một số đặc điểm lâm sàng và kết quả gần cắt gan do ung thư biểu mô tế bào gan. Đối tượng và phương pháp: Nghiên cứu hồi cứu, cỡ mẫu thuận tiện các trường hợp ung thư biểu mô tế bào gan chẩn đoán xác định bằng giải phẫu bệnh. Bệnh nhân được mổ mở cắt gan tại Bệnh viện Bạch Mai từ 4/2016 – 4/2019. Kết quả: 67 bệnh nhân được phẫu thuật. Tuổi trung bình là 56,3 (30 – 76) tuổi. Nam/ nữ = 6,4/1. Triệu chứng đau hạ sườn phải, ăn kém và gầy sút cân lần lượt là 83,6%, 41,8% và 17,9%. Nồng độ AFP huyết thanh trung bình là 635,1 (2,09 – 3968) ng/mL. Nhóm BN có nồng độ AFP < 20, 20 – 400, 401 – 1000, và > 1000 ng/mL lần lượt là 47,8%, 23,9%, 22,3%, và 6%. Kích thước trung bình u trên CLVT và bệnh phẩm lần lượt là 5,4 (2,7 – 8) và 5,3 (2,5 – 8,5) cm. U ở giai đoạn I, II, và III là 17,9%, 62,7%, và 19,4%. Cắt gan nhỏ chiếm 85,1%. Kiểm soát cuống gan chọn lọc, và Pringer lần lượt là 55,2% và 44,8%. Cắt nhu mô gan bằng Ligasure, Kelly + Ligasure, và Kelly lần lượt là 67,2%, 22,4%, và 10,4%. Có 8/67 BN phải truyền máu, chiếm tỷ lệ 11,9%. Lượng máu truyền trung bình là 542,9 mL (250 – 700). Thời gian mổ trung bình là 132,1 phút (90 – 195). Biến chứng sau mổ 17,9%, trong đó tràn dịch màng phổi, suy gan, rò mật lần lượt là 13,4%,1,5%, và 0%. Thời gian nằm viện trung bình sau mổ là 12,8 (6-38) ngày. Kết luận: Ung thư biểu mô tế bào gan diễn biến âm thầm, triệu chứng không đặc hiệu. Bệnh nhân có chức năng gan tốt. Chụp cắt lớp vi tính cho thấy u thường trên 5 cm, có dấu hiệu điển hình của HCC. Cắt gan là phương pháp điều trị hiệu quản, an toàn, biến chứng còn cao nhưng phần lớn là mức độ nhẹ.