bluuebunny/crossref_metadata_2025_split huggingface dataset:
The accuracy of measuring the information parameter of the signal by a tracking meter in aviation and rocket and space technology against the background of additive and multiplicative interference. Measurement of arrival time. Part III
Authors: Артюшенко В.М. , Воловач В.И. 
Published: March 2022

Рассмотрено и проанализировано влияние мультипликативных помех, действующих одновременного с аддитивными помехами, на точность измерения времени прихода информационного сигнала следящим измерителем. Проанализированы зависимости отношения дисперсии измерения времени прихода при наличии мультипликативных и аддитивных помех к дисперсии измерения времени прихода при наличии только аддитивных помех.
The influence of multiplicative interference acting simultaneously with additive interference on the accuracy of measuring the time of arrival of the information signal by the tracking meter is considered and analyzed. The dependences of the ratio of the variance of the arrival time measurement in the presence of multiplicative and additive interference to the variance of the arrival time measurement in the presence of only additive interference are analyzed.
Statistical Control of the Reliability of Rocket and Space Technology Systems with a Consistent Structure at the Stage of Ground Testing
Authors: Рудаков В.Б. 
Published: March 2022

Рассматривается статистический контроль надежности сложных систем ракетно-космической техники (РКТ), состоящих из независимых последовательно соединенных компонент. При этом для компонент и системы в целом проводится контроль совокупностей заданных значений их технических параметров, предшествующий контролю заданного значения показателя надежности системы в целом. Впервые получены математические зависимости для определения достоверности контроля надежности систем с последовательной структурой, которые учитывают результаты предшествующего структурно-иерархического контроля их технических параметров. Практическое использование этих зависимостей приводит к повышению достоверности контроля заданных требований к надежности систем с последовательной структурой, снижению рисков принятия ошибочных решений и сокращению экономических затрат на наземную отработку.
In the article it is considered the statistical control of reliability of complex systems of rocket and space technology (RST) consisting of independent sequentially connected components. At the same time, it is carried out the control of the sets of set values of the technical parameters for the components and the system as a whole preceding the control of the set value of the reliability indicator of the system. For the first time, mathematical dependences were obtained to determine the reliability of reliability control of systems with a sequential structure, which take into account the results of the previous structural and hierarchical control of their technical parameters. The practical use of these dependencies leads to an increase in the reliability of the control of the specified requirements for the reliability of systems with a consistent structure, reducing the risks of making erroneous decisions and reducing the economic costs of ground testing.
Application of clustering and machine learning for building of a recommendation system for determining of scientific articles relevance
Authors: Мосалов О.П. , Иванов И.А. , Першин М.А. 
Published: March 2022

В статье представлено решение задачи построения рекомендательной системы для определения актуальности научных публикаций. Рассматривается алгоритм определения актуальностей, а также применяемые методы машинного обучения для обработки текстовой информации. Рассмотрено и обосновано применение векторных представлений слов и кластеризации.
In the article a solution of a task of developing a recommendation system for determining of scientific article relevance is presented. An algorithm for calculation of relevance and applied methods of machine learning for text data processing are considered. Usage of word embeddings and clustering are justified.
Travma Bilgili Bakım ve Sosyal Hizmet
Authors: GUNES ASLAN Guler 
Published: March 2022

Travma, bireylerin yaşamlarını ve fiziksel bütünlüklerini tehdit eden çeşitli olumsuz olaylar sonucunda ortaya çıkmaktadır. Travma bireylerin sağlığı ve kişiler arası ilişkileri üzerinde kısa ve uzun vadede olumsuz etkiler yapabilmektedir. Travmanın insan yaşamı üzerinde olumsuz sonuçlara neden olması, travmatik yaşam öyküsü olan bireylere yönelik uygulama yaklaşımları geliştirilmesi konusunu da gündeme getirmiştir. Bunun için alanyazında travma bilgili bakım konusu gündeme gelmiştir. Travma bilgili bakım, travmanın yaygınlığının ve etkilerinin farkında olunması ve travma öyküsü olan bireylere yönelik uygulamaların ve kurumsal düzenlemelerin buna göre şekillendirilmesi üzerine inşa edilmiştir. Travma bilgili bakım, travma öyküsü olan birey ve topluluklar hakkında çalışmalar yapılan sosyal hizmet bilimi ve uygulaması için yol gösterici olabilecek bir yaklaşımdır.
Bu çalışmada Amerika Birleşik Devletleri’nde bulunan Madde Bağımlılığı ve Ruh Sağlığı Hizmetleri İdaresi (SAMHSA) isimli kurum tarafından travma bilgili bakımla ilgili ortaya konan varsayım, temel ilke ve uygulama alanlarına yer verilmiş ve sosyal hizmet alanına uyarlanmasına çalışılmıştır. Türkiye’deki alanyazında sosyal hizmet ve travma konusuna yeterince yer verilmediği için, çalışma alanyazına katkı sağlayacaktır
Leakage detection in water distribution networks using space search reduction and local fitness in steady-state and EPS (case study: water distribution network of Birjand)
Authors: Nasirian Ali , Ahrari Marzieh 
Published: March 2022

AbstractUsing hydraulic model calibration of a water distribution network is one of the methods that can reduce leak detection costs by identifying areas with high leakage. In the present paper, a new factor called local fitness is used in combination with the search space reduction method to obtain an optimal answer. In this method, a fitness function is calculated for each zone. For each zone, proximity of the pressure and flow rates obtained from the model to the corresponding observational data indicates that the values selected for the nodes of that zone are close to the correct values. In the next steps, using a search space reduction method and performing the optimization process with the local fitness function, the chance of selecting those values is increased. In this study, leakage was assigned to nodes with emitter coefficient. This method was used on the water distribution network of Birjand. Three factors of background leakage, leakage hotspot and apparent losses were considered as unknown parameters. Results of the present method were compared with the results of a genetic algorithm (GA) and the corresponding exact values. Based the results, the present method showed better results in terms of convergence speed and accuracy.
Functional Models of the Antitumor Antibiotic Bleomycin
Authors: Huang Liren , Quada James C. , Lown J. William 
Published: March 2022

Abstract:
The naturally occurring glycopeptide bleomycin exhibits both antitumor and antibiotic properties. It has an established place in the clinical treatment of certain human malignancies including squamous cell carcinoma and testicular tumors. Structurally it comprises four distinct domains: i) an anchoring group containing a bithiazole moiety that binds to double helical DNA; ii) a chiral peptidic spacer that positions the individual portions of the molecule on the receptor; iii) a sugar moiety bearing a carbamoyl group; and iv) an active moiety bearing ligands capable of coordinating a metal ion, such
as iron and which is involved in the redox chemistry ultimately responsible for site specific DNA
damage. The observation of serious side effects, principally pulmonary toxicity, has limited the clinical applications of bleomycin and provides the motivation to develop less toxic and more selective versions of the drug. Once the mechanism of action of bleomycin via oxygen mediated and site specific DNA cleavage was elucidated the possibility arose of designing functional models. This article will review progress from the earliest metal-complexing models to the most recent conjugates that fully mimic the action of the natural product and, moreover, are capable of being directed to alternative target sequences.
Possible Role of Wnt Signaling Pathway in Diabetic Retinopathy
Authors: Behl Tapan , Mostafavi Ebrahim , Sharma Sheetu , Sehgal Aayush , Singh Sukhbir , Sharma Neelam , Bhatia Saurabh , Al-Harassi Ahmed , Bungau Simona 
Published: March 2022

Abstract:
The core of impaired vision in working people suffering from insulin-dependent and non-insulin-dependent diabetes mellitus is diabetic retinopathy (DR). The Wnt Protein Ligands family influences various processes; this ensures the cells are able to interact and co-ordinate various mobile functions, including cell growth, division, survival, apoptosis, migration, and cell destiny. The extra-cellular Wnt signal activates other signals. It is seen that Wnt pathways play an important role in in-flammation, oxidative stress, and angiogenesis. It has been illustrated that the canonically preserved Wnt signaling system has a vital role in the homeostasis of adulthood. Developmental disorders in each of these stages will lead to serious eye problems and eventually blindness. There is, therefore, a need to specifically organize and regulate the growth of ocular tissues. In tissue specification and polarities, axonal exhaust, and maintenance of cells, especially in the central nervous system, Wnt/frizzled pathways play an important role. Thus, Wnt route antagonists may act as have been possible therapeutic options in DR by inhibiting aberrant Wnt signals. Elaborative and continued research in this area will help in the advancement of current knowledge in the field of DR, and even-tually, this can lead to the development of new therapeutic approaches.
The Value of Serum Fibrinogen/Uric Acid Ratio as a Novel Marker of Fetal
Growth Restriction in Preeclampsia at 34 Weeks
Authors: Nori Wassan , Ibrahim Ali Alaa , Ismael Wisam Akram 
Published: March 2022

Background:
Fetal growth restriction (FGR) is a common alignment that complicates pregnancy,
especially for preeclampsia cases; therefore earlier detection is crucial to improve the outcome.

Objective:
We examine whether the ratio of maternal serum fibrinogen to serum uric acid (ms F/U)
can serve as a marker FGR in patients with preeclampsia at 34 weeks.

Material and Methods:
A cross-sectional study recruited 98 preeclamptic primigravidae at the University
Teaching Hospital from June 2018 to June 2019. Patients were sent for laboratory and ultrasound
examinations. Maternal parameters include systolic and diastolic blood pressure, serum fibrinogen,
and serum uric acid. Ultrasonic fetal parameters include amniotic fluid index AFI, estimated
fetal weight EFW, pulsatility index PI, and resistance index RI.

Results:
Pearson’s correlation between ms F/U ratio and all other feto-maternal variables was significant
as P value was <0.0001. The ms F/U ratio showed strong positive correlations with EFW and AFI.
The ms F/U ratio showed strong inverse correlations with PI, RI, systolic, diastolic blood pressure, and
albumin/creatinine ratio. The strength of association tested by a coefficient of Mallow showed the
strongest association between ms F/U versus fetal weight. The highest Odd ratio for FGR was 45, associated
with the ms F/U ratio. The cutoff value for ms F/U ratio was 26.08 mg/dL with an estimated sensitivity
and specificity of 85% and 96.25%, respectively, with an AUC of 0.82.

Conclusion:
Strong and significant correlation of ms F/U ratio with feto-maternal parameters at high
sensitivity and specificity added to its simplicity, and cost-effectiveness makes ms F/U ratio a reliable
marker for earlier FGR to improve the outcome.
Utility of Acceptance and Commitment Therapy Among Adolescents - A Systematic Review
Authors: Baveja Divya , Shukla Jyotsana , Srivastava Srishti 
Published: March 2022

Background:
Acceptance and Commitment Therapy (ACT) is one of the third
wave therapies that came as a response to certain limitations of cognitive-behavioral therapies
and other existent psychotherapeutic models, which emphasizes changing the context
of cognition rather than the content. ACT has a fast-growing evidence base, and its literature
among the adolescent population is in its infancy.

Objective:
The authors attempted to consolidate findings of ACT’s effectiveness for clinical
problems among the adolescent population.

Methods:
Electronic databases of PubMed, PsycArticles, PsycINFO, Sage, and ProQuest
were searched for published studies and unpublished doctoral dissertations until April 2021.
After adopting a two-staged screening process, 19 studies were selected, which included
randomized controlled trials, case reports, and other quasi-experimental studies reporting
results from ACT or ACT-based intervention given to a population of adolescents for any
clinical conditions or concern. The authors present a narrative systematic review of these 19
studies, including a methodological assessment.

Results:
Results showed ACT to be effective in reducing objectively measured clinical
symptoms and interference caused by them. Subjective accounts by adolescents and caregivers
also corroborated that. More rigorous RCTs and comparisons with other active treatments
are needed to improve the evidence base as such studies were few and had some
methodological flaws. The authors also discuss certain limitations in assessing the effectiveness
of ACT in such studies.

Conclusion:
The ACT model could serve as a promising alternative approach to be used
with adolescents across many concerns, with an emphasis on improving the quality of life
and their engagement with valued goals.
A Method based on Faster RCNN Network for Object Detection
Authors: Cao Danyang , Yang Shaobo 
Published: March 2022

Background:
Detecting occluded objects in images remains a challenging problem
since the occluded objects often occlude each other or are occluded by other objects. It is hard to
identify the occluded objects in an image, especially when the occlusion is significant.

Methods:
In this work, a two-stage object detection method has been proposed. The proposed
method is based on the Faster RCNN model and uses ResNet50 as the backbone network. In
addition, the method uses the feature pyramid network to reuse the higher-resolution maps of the
feature hierarchy. The dilated convolution in the architecture of the proposed network has been
added to expand the receptive field of the feature maps and the loss function and gradient
learning rate are optimized.

Result:
The proposed detector is trained in an end-to-end fashion, which achieves state-of-theart
results on two datasets, i.e., MAFA and WIDER FACE, particularly for WIDER FACE (with
the highest mAP, 66.4%).

Conclusion:
In conclusion, by adding dilated convolution and optimizing gradient learning rate
to the object detection model, the precision of the occlusion object detection can be improved
effectively.
Manganese-Iron Mixed Oxides of Spinel Structure
as Soot Combustion Catalysts
Authors: Legutko Piotr , Zwada Natalia , Kozieł Marcin , Michalik Marek , Adamski Andrzej 
Published: March 2022

Background:
An abatement of emission of particulate matter (mainly soot) is a challenging problem of nowadays society. An active and cheap catalytic system for soot combustion can help in solving this problem.

Objective:
The aim of this study was to investigate influence of composition of Mn3-xFexO4 (x = 0 – 3) oxides exhibiting spinel structure on their catalytic properties in soot combustion.

Methods:
Materials were synthesized by coprecipitation and further thermal treatment. Their structure was verified by X-ray diffraction and Raman spectroscopy. The obtained catalysts were tested in model soot oxidation (Printex U) in both tight and loose contact modes.

Results:
It was found that different mechanisms of soot combustion occurred dependently on a chosen contact mode.

Conclusion:
It was confirmed that in the case of tight contact (TC) a coexistence of divalent manganese and iron species was decisive for catalytic activity, whereas a presence of trivalent manganese centers was crucial in the case of loose contact (LC). Mn1.2Fe1.8O4 was found to be the most active catalyst.
A Review of Neuroreceptors for Clinical and Experimental Neuropharmacology
in Central Nervous System Disorders
Authors: McKarns Susan C. 
Published: March 2022

Abstract:
The neurobiology drug discovery landscape has transformed over the past decade or so by
the discovery of allosteric modulators of receptor superfamilies. A wide range of physiological reactions
can occur in response to a limited number of neurotransmitters. This review provides an update
on physiological features of the receptors and the signaling pathways that are generated in response to
neuroreceptor activation that allow the explanation of this vast array of neurotransmitter responses.
Primarily based upon structure, receptors in the nervous system can be classified into four groups: Gprotein
coupled receptors, ligand-gated receptors, enzyme-linked receptors, and nuclear receptors.
With a particular emphasis on the central nervous system, i.e., brain, spinal cord, and optic nerves, we
identify the neuroreceptors, their endogenous agonists, antagonists, sites of expression within the
nervous system, current neuropharmacological clinical use, and potential for new drug discovery. New
molecular approaches and advances in our knowledge of neuronal communication in processes involved
in development, functioning and disorders of the nervous system combined with opportunities
to re-purpose existing drugs for new indications continue to highlight the exciting opportunities to improve
human health.
Tanggapan Aksesi Kacang Hijau (<i>Vigna radiata</i> L.) terhadap Mikoriza di Lahan Sawah Bekas Padi
Authors: Izzudin Hafidh , Taryono Taryono , Widyawan Muhammad Habib 
Published: March 2022

Produksi kacang hijau nasional menurun selama kurun waktu tahun 2016 – 2018. Salah satu usaha untuk meningkatkan produktivitas tanaman secara ramah lingkungan adalah menambahkan agen hayati-mikoriza, karena pemberian mikoriza mampu meningkatkan pertumbuhan serta komponen hasil tanaman. Penelitian ini bertujuan untuk mengetahui tanggapan beberapa aksesi kacang hijau terhadap inokulasi mikoriza serta memilih aksesi yang tanggap terhadap inokulasi mikoriza sebagai bahan kajian genetika dan fisiologi ketergantungan kacang hijau terhadap mikoriza. Penelitian dilaksanakan di lahan Pusat Inovasi Agroteknologi Universitas Gadjah Mada (PIAT-UGM) Kalitirto, Berbah, Sleman, Yogyakarta menggunakan rancangan acak lengkap (RAL) petak terbagi yang terdiri atas dua faktor. Faktor utama yaitu perlakuan inokulasi dan anak faktor berupa 20 aksesi kacang hijau. Pengamatan meliputi infeksi mikoriza, sifat komponen hasil, dan hasil. Data yang diperoleh selanjutnya dianalisis menggunakan analisis varian sesuai rancangan acak lengkap, uji lanjut Scott Knott, dan analisis korelasi. Pada penelitian ini masing-masing nomor aksesi kacang hijau memiliki tanggapan yang beragam terhadap inokulasi mikoriza. Persentase infeksi mikoriza lebih tinggi pada perlakuan inokulasi. Inokulasi mikoriza mampu meningkatkan jumlah polong per tanaman, biji per polong, dan bobot biji per tanaman, namun tidak dengan bobot 100 biji tanaman. Persentase infeksi mikoriza pada umur 20 hari setelh tanam nyata berhubungan dengan hasil biji. Hasil penelitian memberikan informasi bahwa nomor aksesi 788, 797, 798, 805, 807, 810, 812, 826, 829, dan 832 berpotensi untuk dikembangkan sebagai bahan kajian genetika dan fisiologi ketergantungan kacang hijau terhadap mikoriza.
Customer loyalty model: a custom product perspective, innovation adaption, brand image, lifestyle, and trust in the interior furniture industry
Authors: Candri Feno , Yacob Syahmardi , Junaidi Junaidi , Lubis Tona Auora 
Published: March 2022

Custom Interior Furniture is a product made and produced based on consumers' demands. It has become a new phenomenon where customers are now more interested in a product representing owners' hopes and desires. It indeed cannot be separated from the patterns and lifestyles of people who are increasingly open in accepting the development of information technology, where access to information about interior design furniture is straightforward to obtain. Therefore, it makes a new trend rapidly influencing the paradigm of modern society today about interior design, especially custom interior furniture products. This study uses a Literature Review approach which reviews and discusses a series of Custom Products with references from existing articles. The selected variables are Custom Products, Innovation Adaption, Brand Image, Life Style, Trust, and Customer Loyalty.
EFEKTIVIFAS TERAPI KOMBINASI PEMBERIAN SEDUHAN KEMBANG TELANG/BUTTERFLY PEA (CLITTORIA TERNATEA) DAN LAMAZE EXERCISE TERHADAP PENURUNAN NYERI HAID (DISMENOROE) PADA REMAJA PUTRI
Authors: Sembiring Julina Br , Kadir Dalimawaty , Tarigan Rahmawati 
Published: March 2022

Dismenore membuat remaja putri tidak bisa beraktivitas secara normal dan memerlukan resep obat. Tujuan penelitian untuk mengetahui Efektivitas kombinasi Pemberian Seduhan Kembang Telang/Butterfly Pea (Clittoria Ternatea) dan Lamaze Exercise terhadap penurunan intensitas nyeri haid pada remaja putri di Desa Lau Mulgap . Desain penelitian Quasi Eksperimen dengan one group pretest-posttest design, melibatkan 43 remaja putri. Teknik sampling menggunakan purposive sampling. Hasil uji paired t-test diperoleh nilai p=0.000(<0.05), menunjukkan Efektivitas kombinasi Pemberian Seduhan Kembang Telang/Butterfly Pea (Clittoria Ternatea) dan Lamaze Exercise efektif dalam menurunkan intensitas nyeri haid. Hasil penelitian perbedaan intensitas nyeri haid sebelum dan sesudah intervensi, maka dilakukan uji statistik Paired t-test . Berdasarkan hasil uji statistik diperoleh nilai rata-rata intensitas nyeri haid saat Pre intervensi adalah 2.37 dengan SD 0.926, sedangkan saat dilakukan Post intervensi, nilai rata-rata nyeri haid menjadi 1.950 dengan SD 0.950. Secara statistik nilai rata-rata perbedaan antara pre intervensi dan post intervensi adalah 0.419 dengan nilai p value yaitu 0.013, maka dapat disimpulkan nilai P<0.05. Nilai tersebut menunjukkan adanya perbedaan yang signifikan antara rata-rata nyeri haid sebelum dan sesudah dilakukan terapi kombinasi. Dapat disimpulkan nyeri haid menurun setelah dilakukan terapi kombinasi Pemberian Seduhan Kembang Telang/Butterfly Pea (Clittoria Ternatea) dan Lamaze Exercise terhadap penurunan intensitas nyeri haid.