bluuebunny/crossref_metadata_2025_split huggingface dataset:
Type 1 diabetes mellitus in children and adolescents: risk factors
Authors: Bagatska N.V. , Glotka L.I. 
Published: December 2022

Objective — to study the risk factors for the formation of type 1 diabetes mellitus (DM 1) in children and adolescents.
Materials and methods. Genealogical analysis was carried out in families of 70 children and adolescents with DM 1 of both genders, aged 8 to 18 years, who were examined in the Institute of Children and Adolescents Health Care of the NAMS of Ukraine. The comparison group consisted of pedigrees of 82 healthy peers, residents of Kharkiv and Kharkiv region. The collection of pedigrees was carried out by the generally accepted method. Statistical processing of the obtained data was carried out using the Student’s criterion in the Excel application package.
Results and discussion. Based on genealogical analysis, the predominance of the following endogenous and exogenous factors in families of DM 1 patients was revealed when compared to the similar factors in families of healthy probands: stress before pregnancy and pathological course of childbirth in mothers; tobacco smoking in fathers; artificial feeding, stress, bad habits, surgical interventions, additional load in children. Among the different categories of relatives of DM 1 patients, endocrine diseases prevailed in mothers compared to fathers, in grandmothers in comparison with grandparents and aunts versus uncles. It was determined that 2.9 % of families of patients had hereditary burden for DM 1, 51.4 % of families for type 2 DM, and 4.3 % of families for both type 1 and type 2 diabetes. Relatives of probands with type 1 diabetes demonstrated prevalence of endocrine, cardiovascular, mental and oncological diseases and pathology of the digestive system compared to the frequency of these diseases in relatives of healthy peers.
Conclusions. According to the results of the research, endogenous and exogenous risk factors, and family accumulation of multifactorial diseases (endocrine, cardiovascular, mental and oncological diseases and pathologies of the digestive system) in the pedigrees of children and adolescents with type 1 diabetes have been established.
APLIKASI PORTAL DESA PADA LOKASI KULIAH KERJA NYATA UNIVERSITAS MADURA
Authors: Zain Muhammad Yasir , Eka Putra Fauzan Prasetyo , Ridwan Fahrur 
Published: December 2022

ABSTRACT
Students from the Informatics Engineering Real Work Lecture (KKN) and the Madura University service team will work together to create a website application implementation strategy that will be used to disseminate information throughout the village (Unira). Researchers hope to develop training plans for village website managers in Pamekasan Regency using the results of their research. A content management system was developed to provide information about village advantages to the general public. This system includes several menus, including village profiles, village administration, community assets, community data, community maps, and community news. This information can be found on the site. The main purpose of this system is to inform the general public about the benefits of the community. Regarding the implementation of the study, the Unira service team developed and trained the CMS, the Madura University Research and Community Service Institute (LPPM) prepared the domain and hosting, and the Real Work Lecture (KKN) students assisted in website administration (INF).
Keywords: village-portal, village website.

ABSTRAK
Mahasiswa dari Kuliah Kerja Nyata (KKN) Teknik Informatika dan tim pengabdian Universitas Madura akan bekerja sama untuk membuat strategi implementasi aplikasi website yang akan digunakan untuk menyebarluaskan informasi ke seluruh desa (Unira). Peneliti berharap dapat mengembangkan rencana pelatihan bagi pengelola website desa di Kabupaten Pamekasan dengan menggunakan hasil penelitian mereka. Sebuah sistem manajemen konten dikembangkan untuk memberikan informasi tentang keunggulan desa kepada masyarakat umum. Sistem ini mencakup beberapa menu, antara lain profil desa, pemerintahan desa, aset komunitas, data komunitas, peta komunitas, dan berita komunitas. Informasi ini dapat ditemukan di situs. Tujuan utama sistem ini adalah untuk menginformasikan masyarakat umum tentang manfaat komunitas. Terkait pelaksanaan kajian, tim pengabdian Unira mengembangkan dan melatih CMS, Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Madura menyiapkan domain dan hosting, dan mahasiswa Kuliah Kerja Nyata (KKN) membantu administrasi website (INF) .
Kata Kunci: portal-desa, website desa.
АНАЛІЗ ЗАКОРДОННОГО ДОСВІДУ ФОРМУВАННЯ МЕДІАГРАМОТНОСТІ МОЛОДІ
Authors: Руденко Юлія , Овчаренко Володимир 
Published: December 2022

Показано прямий зв’язок між глобальною цифровізацією суспільства і важливістю навчання медіаграмотності населення. Представлена змістовна характеристика термінів «медіаосвіта» та «медіаграмотність». Через історичний дискурс дефініцій і порівняння їх розуміння в різних державах зроблено висновок про відсутність принципової різниці у тлумаченнях, уточнено, що прийнято вважати медіаосвіту як процес освіти, а медіаграмотність як її результат. Акцентовано увагу на особливості формування медіаграмотності в Україні з у рахуванням інформаційних небезпек, що створені воєнною агресією РФ.
Сформовано уточнення термінів «медіаосвіта» і «медіаграмотність». Медіаосвіта - це освіта, спрямована на формування медіаграмотності, яку, у свою чергу, трактуємо як сукупність знань, компетентностей і практик критичного оцінювання медіа із розумінням їх соціокультурного і політичного контексту, навички відповідального споживання, поширення і створення медіаповідомлень; здатність взаємодії у медіапросторі на творчій, законній і етичній основі; уміння протистояти агресивним і деструктивний інформаційним впливам та захищати свій інформаційний простір.
Розглянуто передовий досвід формування медіаграмотності у Великій Британії (навчання і розвиток «критичної грамотності» і «функціональної грамотності»); США (масовий характер, пріоритет для всіх верств населення; практична спрямованість; практика інтеграції елементів критичного мислення практично в усі навчальні дисципліни); Франції (тренінги викладачів і консультантів з медіаграмотності; генерація педагогічних ресурсів з навчання медіа та інформаційної грамотності; розвиток медіатворчості в школах та університетах); Швеції (державна підтримка; просвітницька діяльність з формування критичного мислення ЗМІ, освітніх закладів, Державної медіаради тощо); Канади (медіаграмотність – обов’язковий компонент всіх навчальних дисциплін; поширення практики навчання візуальній медіаграмотності). Розглянуто приклади впровадження медіаграмотності як процесу самоосвіти у західноєвропейських країнах (Німеччина, Данія, Бельгія, Нідерданди). Представлено погляд на медіаграмотність прибалтійських країн (діє система додаткового навчання засобами неформальної освіти протягом усього життя). Основна увага приділяється контрзаходам проти російської деструктивної пропаганди, формуванню критичного мислення, способам уникнення негативних впливів на свідомість особистості.
Узагальнено досвід країн для впровадження його ефективних надбань у медіасвіту українських вищих освітніх закладів.
दनुवारी र नेपाली भाषाका शब्दवर्गको तुलना {Comparison of word classes of Danuwari and Nepali languages}
Authors: अर्याल Aryal पदमप्रसाद Padam Prasad 
Published: December 2022

प्रस्तुत आलेख दनुवारी र नेपाली भाषाका शब्दवर्गको तुलना गर्ने उद्देश्यले तयार पारिएको छ । तुलनात्मक अध्ययनका लागि नवीन तथा स्पष्ट सैद्धान्तिक पर्याधारको अभावमा मूलत: विद्वान्हरूका परम्परित नेपाली व्याकरणानुसार शब्दले गर्ने कार्यका आधारमा उक्त दुई भाषाका शब्दवर्गलाई तालिकीकरणका माध्यमबाट आलेखन गरिएको छ । पदवर्गभित्रका नाम, सर्वनाम, विशेषण, अव्यय, निपात र क्रियावर्ग र यसका भेदोपभेदको पनि तुलना गरिएको छ । यसका साथै क्षेत्रीय अध्ययन गरी प्राप्त प्राथमिक सामग्रीहरूलाई वर्गीकरण गर्न र अन्य आवश्यक ज्ञानका लागि पुस्तकालयीय विधिको प्रयोग पनि गरिएको छ । यस आलेखको प्राविधिक कार्यलाई पूर्णता प्रदान गर्न एपिए सातौँ संस्करणका प्रावधानलाई यथाशक्य उपयोग गरिएको छ । नेपाल विभिन्न जातजातिको सङ्गमस्थल हो । नेपालका प्रमाणित भाषा १२३ छन् भने भाषा –आयोगले नयाँ आठ वटा भाषाहरूको सूची प्रकाशित गरेको छ । दुवैलाई जोड्दा नेपालमा १३१ भाषा अस्तित्वमा छन् । यीमध्ये दनुवार जाति र यसको भाषा पनि एक राष्ट्रिय भाषा हो । दनुवारी भाषी नेपालका सातै प्रदेशमा छरिएर बसेका भए पनि यिनको मुख्य उद्गम स्थल र अधिक सङ्ख्यामा बसोबास चाहिँ वाग्मती प्रदेशमा नै भएको तथ्याङ्क प्राप्तछ । दनुवारी र नेपाली यी दुई भाषाका शब्दवर्गको तुलना गर्न सैद्धान्तिक आधारको आवश्यक पर्छ तर भाषाको तुलना गर्ने ठोस प्रकारको सैद्धान्तिक आधारको अभाव भएको हुँदा मूलतः परम्परित व्याकरण र आंशिक रूपमा तालिकीकरणका माध्यमबाट प्रस्तुत गरिएको छ । परम्परागत व्याकरणको शब्दवर्गको सैद्धान्तिक आधारमा दनुवारी र नेपाली भाषाका शब्दवर्गलाई तुलना गरिएको छ । दनुवारी भाषाका नाम वर्ग र विभिन्न उपवर्गमा अन्य भाषाको बढी मात्रामा प्रभाव परेको छ तथापि यो भाषा शब्दभण्डारका दृष्टिले निकै सबल छ । नातागोता, शरीरका विभिन्न अङ्ग, लुगाफाटा गरगहना,रोग, कृषिसँग सम्बन्धित शब्दहरू, नेपाली भाषासँग सम्बन्धित शब्दहरू, बोटविरुवा, कीटपतङ्ग, घरेलु सामग्री,पशुपंक्षी रखानेकुरा आदिका नाम शब्द सबै प्रकारका शब्दहरू प्रशस्त मात्रामा रहेको पाइएको छ । उक्त किसिमका शब्दहरू नेपाली निकटवर्ती भाषासँग पूर्ण भिन्नता, आंशिक समानता र पूर्ण समानता तिनै किसिमका समानता भएको कुराको निरूपण गरिएको छ । दनुवारी भाषा पनि नेपाली भाषाको तीव्र प्रभावमा रहेको स्थिति छ । नयाँ पुस्ताले लिइरहेको आधुनिक शिक्षा, बसाइँ सराइ, सञ्चार माध्यम मातृभाषाको प्रयोगमा कमी आदि कारणले यो भाषाले मूलत: नेपाली भाषाकै प्रभाव र स्वभाषेतर प्रयोगका कारणले आफ्नो मौलिकपन दिनानुदिन गुमाइरहेको छ ।
Nutritional and Antinutritional Analysis of Dawadawa Condiment in Aliero Local Government, Kebbi State, Nigeria
Authors: Ahmad A , Keta J.N. , Singh Dharmendra , Hassan S.R , Ibrahim M 
Published: December 2022

Dawadawa is among the most important soup ingredients in Aliero, Kebbi State, Nigeria. The locally produced condiment is being prepared and used to add flavor to soup for many decades without the scientific knowledge of its nutritional and anti-nutritional contents. This study aimed to analyze the proximate and antinutrional contents of Dawadawa in Aliero Local Government, Kebbi State, Nigeria. Five samples from each four collection areas were collected and transported to Botany Laboratory, Kebbi State University of Science and Technology Aliero for analysis. Analysis of the proximate and antinutrient parameters were carried out using the AOAC (Association of Official Analytical Chemists) recommended techniques. The result of the study revealed that the condiments had high moisture contents (33.34 + 2.09) followed by protein (29.37 + 1.31), fibre (13.07 + 0.54), carbohydrate (12.83 + 1.34), lipid (8.92 + 1.75) and ash (2.49 + 0.83). While the results antinutrional analysis revealed that that Cyanide has the highest composition (4.81 + 0.33) followed by Oxalate (4.07 + 0.50), Phytate (3.01 + 0.19) and Saponins (2.90 + 0.36). It was found that Dawadawa condiments have high nutritional contents with low level of antinutrients. In view of the high nutriental content and low antinutriental content, it is recommended that Dawadawa should be used as substitute to the monosodium glutamate-based seasoning salts.
RESEARCH OF BURNING OF AGRICULTURAL PELLETS IN BOILERS WITH CAPACITY UP TO 25 kW
Authors: Lysenko O.M. , Veremiichuk H.M. , Siryi O.A. 
Published: December 2022

The main purpose of this research is to determine the main dependence’s of the agricultural pellets combustion process and to study the influence of regime parameters on the distribution of temperatures in the combustion chamber, as well as to analyze the biofuels productivity characteristics.
Research methods: experimental and theoretical.
Results. The research of biofuel combustion process was carried out at the experimental facility of solid fuel boiler with a pellet burner for a passive type house heating. During experimental researches samples of wood pellets, rapeseed pellets and beets pulp were used. On the received graphs the changes in the temperature state of the combustion chamber at the stage of pelletʼs ignition, burning and fading were reflected. It was found that the largest increase in temperature occurs near the wall of the boiler, which is opposite to the burner. As can be seen on the graphs, temperature fluctuations occur as a result of the periodic burning of biofuel in the burner and the arrival of a new portion of pellet from the hopper. As the experiments showed, the temperature level at burning of rapeseed pellets is much lower than in comparison with wood pellets, and to go to the established mode of burning of beet pulp pellets is generally problematic. It is obvious that when setting up the fuel supply system and modes of operation of the fuel it is necessary to take into account heat physical characteristics of fuel, first of all moisture and heat capacity, as well as yield of volatile combustible components. For this purpose, a gas analysis was carried out when burning wood pellets. The selection of combustion products was done in the wild immediately after the boiler. As a result, the NOx and CO concentrations of the appropriate temperature were obtained at the sample site. The nitrogen oxide concentrations should be considered moderate, which cannot be argued about the concentration of carbon monoxide, which requires further research. The obtained results can be used to increase the efficiency of combustion process at burning biofuel in boilers of low power communal and industrial heat power, social-budget sphere and individual-household sector.
DETERMINATION OF KINETIC CHARACTERISTICS OF SOLID FUEL.
Authors: Chmel V.N. , Novikova I.P 
Published: December 2022

The combustion process begins with the ignition of the fuel - bringing it to the auto-ignition temperature, which is one of the important components of the kinetic characteristics of the fuel.
Fuel ignition does not occur immediately - but after a certain period, during which activation energy is accumulated: heat or active centers, depending on the mechanism of the process - thermal-kinetic or chain-kinetic, sufficient to overcome the potential barrier. At the same time, the period of reaching the self-ignition temperature is the induction period of this reactive system: for self-ignition or the ignition time during ignition.
The purpose of the work is to substantiate the kinetic characteristics of the fuel: self-ignition temperature and induction period, methods of their experimental determination for solid fossil fuels and biomass waste.
According to the methodology, an installation was created for the experimental determination of the self-ignition temperature and the induction period of solid fuel in the layer.
Studies of such fuels as anthracite, hard coal, buckwheat husk, millet, oats, flax husks, birch wood, peat, and paper showed the dependence of the self-ignition temperature on the degree of metamorphosis and volatiles. With an increase in the degree of metamorphism and a decrease in volatiles in solid fuel, the self-ignition temperature increases. However, the self-ignition temperature does not depend on the size of its particles, their number in the layer and the temperature of the oxidizer.
The above allows us to conclude that the self-ignition temperature depends only on the conditions of heat exchange (accordingly, on aerodynamics), and the absolute value of the auto-ignition temperature for an infinite space, in the absence of a jet stream, is a constant value, and only then, in the presence of heat exchange (with velocity gradients) , takes one or another value.
It was found that the induction period depends only on the initial temperature of the process, the induction period decreases with increasing temperature. This is due to the more intensive transfer of heat to the fuel particles due to the increase in the temperature gradient and the acceleration of the development of the oxidation reaction.
The induction period, as shown by the conducted experiments, does not depend on the size of the particles. This can be explained only by the fact that the rate of thermal destruction of the fuel is close to the rate of its heating. The burning time of coal particles, on the contrary, depends on the size of its particles.
Expressions for determining the autoignition temperature and the induction period were obtained based on the processing of the results of the conducted experiments.
The results of the work can be used in combustion technologies, in which self-ignition of fuel is one of the main components of the process - it ensures combustion in the self-ignition mode of fuel when in contact with an oxidizer.
A TRILHA DO TATU (ANÁPOLIS - GO):
Authors: TAVARES ADRYELLY MOREIRA , SOUSA CLAUDIO FERNANDES DE , DARIM ELISA PARREIRA , MACÊDO THIAGO PRUDENTE DE , CARNEIRO VANDERVILSON ALVES 
Published: December 2022

Resumo: A Trilha do Tatu, na UEG - Universidade Estadual de Goiás, Campus de Ciências Exatas e Tecnológicas Henrique Santillo (CET), Anápolis / GO, materializa-se como um ambiente não formal e com potencialidades de ensino-aprendizagem. Assim, este estudo foi desenvolvido com o objetivo de reconhecer as fitofisionomias do Cerrado, a fisiografia e a ação antrópica do lugar via leitura visual da paisagem e registrar os elementos e/ou fatores relevantes que caracterizam a Trilha do Tatu como uma unidade de preservação ambiental. À luz de um trabalho de campo realizado em 19/02/2019, em uma ação pedagógica da disciplina de Fundamentos em Gestão Ambiental, do curso de pós-graduação Lato Sensu em Gestão Ambiental ficou evidenciado que a Trilha do Tatu constitui-se em um espaço não formal singular que proporciona a mediação do conhecimento in situ, a céu aberto em um prisma vivencial e que configura uma possibilidade didático-pedagógica para a construção de conhecimentos com foco tanto na teoria em sala como na prática in loco.
Palavras-chave: Trilha ecológica; Trabalho de campo; Ensino; Cerrado.
A complete thrombotic large aneurysm at the nonbranching segment of the distal anterior cerebral artery mimicking a cavernous malformation: illustrative case
Authors: Hirokawa Yu , Michiwaki Yuhei , Tanaka Tatsuya , Kawashima Masatou , Wakamiya Tomihiro , Sashida Ryohei , Shimoji Kazuaki , Suehiro Eiichi , Onoda Keisuke , Yamane Fumitaka , Matsuno Akira 
Published: December 2022

BACKGROUND
Thrombotic aneurysms at the nonbranching segment of the distal anterior cerebral artery (ACA) are extremely rare and difficult to differentiate from cavernous malformations by radiographic features alone.

OBSERVATIONS
Computed tomography and magnetic resonance imaging of a 30-year-old female patient with a chronic headache complaint revealed a 22-mm frontal lobe mass. The mass showed heterogeneous mixed intensity and hemosiderin deposits on magnetic resonance images. It was not visualized by conventional angiography, indicating that the mass and ACA/other vessels were not connected. The patient was preoperatively diagnosed with a cavernous malformation. However, during resection, the mass surface was white and smooth, different from a cavernous malformation. Although the mass was adherent to the pericallosal artery branch, no luminal continuity was observed. After detachment, the mass was completely resected. Pathological and immunohistochemical findings indicated a vessel wall and interior thrombus. The patient was rediagnosed with a thrombotic aneurysm at the distal ACA nonbranching segment and discharged 10 days postsurgery without neurological deficits.

LESSONS
Because radiographic findings of thrombotic aneurysm and cavernous malformation are similar, mass lesions in contact with major arteries should be differentiated as thrombotic aneurysms, even when the artery lumen appears disconnected from the mass.
High SNAIL Expression Reflects Of Recurrence After Resection Colorectal Cancer Liver Metastasis
Authors: KARAMUSTAFAOĞLU Ahmet , AK AKSOY Secil , TUNCA Berrin , ERÇELİK Melis , TEKİN Çağla , UĞRAŞ Nesrin , YERCİ Ömer , AKSOY Fuat , KAYA Ekrem 
Published: December 2022

Introduction: Metastasectomy is one of the effective treatment methods for liver metastases developing from primary colorectal cancer (CRC). However, recurrence after metastasectomy is the biggest problem in these cancers.
The present study aimed to examine the role of Epithelial-Mesenchymal Transition (EMT) in the development of recurrence after metastasectomy in liver metastases from primary CRCs.
Materials and Methods: In the study, 85 patients were evaluated. RNA was isolated from archive tumors and normal tissues of the patients. Expression profiles of 7 different EMT markers were examined using qRT-PCR.
Results: Metastasis to the liver developed in 24.7% (n=21) of 85 CRC. Recurrence was observed in 42.3% (n=9) of liver metastases after metastasectomy. Statistically significant increases were detected in the expression of EMT markers TWIST and SNAIL in the development of mCC in primary CRC (p
THE EFFECT OF DRILL SHOOT TRAINING METHOD ON BOLABASKET TWO-POINT SHOOTING SKILLS
Authors: Latuheru Ricardo Valentiono , Sahabuddin Sahabuddin , Herman H 
Published: December 2022

This study aims to determine the influence of the drill shoot training method on basketball two-point shooting skills in extracurricular students of SMA Negeri 5 Makassar. This research is a type of experimental research, the population of this study is students of SMA Negeri 5 Makassar who participated in basketball extracurriculars, with a total sample of 20 students selected by random sampling. The data analysis techniques used are descriptive, normality, homogeneity, and t-test using SPSS Version 22.00 at a significant level of 95% or αo,o5. Based on the results of data analysis, this study concluded that there was an influence of the drill shoot training method on basketball two-point shooting skills in extracurricular students of SMA Negeri 5 Makassar experimental group as evidenced by an increase from a value of 24.20 increased to 26.85, with a calculated t value of 17, 667 and t table 2,093 (df 19).
PEMBUATAN POMPA AIR TANPA LISTRIK (RAM PUMP) (Studi Kasus Kecamatan Malausma)
Authors: AKMAL AKMALUL AKHLAK 
Published: December 2022

ABSTRACT
Ketersediaan air yang cukup dan terus menerus merupakan salah satu faktor penting yang mempengaruhi keberhasilan usaha di bidang pertanian dan perikanan. Selama ini usaha pertanian dan perikanan masih bergantung terhadap air hujang yang terjadi pada musin tertentu. Karena musim hujan tidak terjadi sepanjang tahun, maka usaha pertanian dan perikan di lokasi studi kasus
(Desa Buninagarat Kabupaten Majalengka) tidak dapat berlangsung secara berkesinambungan dalam satu tahun penuh. Oleh karena itu, tujuan utama artikel ini adalah membahas tentang penerapan pompa hydraulic ram pump (hydram) untuk memenuhi kebutuhan air di lokasi studi kasus mitra pertanian dan mitra perikanan tersebut. Pemilihan pompa hydram untuk menjamin ketersediaan air adalah bahwa teknik ini tidak membutuhkan sumber tenaga listrik sehingga dalam pengoperasiannya akan memberikan penghematan biaya operasional dan ramah terhadap lingkungan. Selain itu, artikel ini juga menganalisis tahapan demi tahapan pembangunan poma hydram hingga dapat beroperasi sesuai dengan rancangan yang telah dibuat. Dari hasil pengukuran yang diperoleh didapatkan kinerja pompa hydram adalah 1 L/35,7 detik sehingga untuk mengisi 2 buah tanki

air dengan kapasitas total 2.100 L dibutuhkan waktu pengisian selama jam.