bluuebunny/crossref_metadata_2025_split huggingface dataset:
ADESÃO DE ADOLESCENTES OBESOS ÀS AÇÕES DE PROFISSIONAIS DE SAÚDE NA ATENÇÃO PRIMÁRIA EM SAÚDE
Authors: Carvalho Rodrigues Layonne de Sousa , Batista Beserra Jéssica , Araujo de Sousa Roniele , De Oliveira Cardoso Osmar , Melo dos Santos Marize 
Published: January 2025

Este artigo associou a percepção de profissionais de saúde acerca da adesão de adolescentes obesos às ações realizadas na atenção primária em saúde. Trata-se de estudo descritivo, temporalidade transversal e abordagem quantitativa realizado com dados do “Programa de enfrentamento e controle da obesidade, no âmbito da Atenção Básica do SUS”, no Piauí, entre março e outubro de 2021. Profissionais de saúde responderam questionário eletrônico sobre as ações em âmbito individual, em grupo e comunitário, bem como sobre sua adesão. Os dados foram analisados no programa Stata, versão 14. Observou-se que as ações mais prevalentes, no cuidado em grupo, foram as de Promoção da Alimentação Adequada e Saudável (33,88%) e as orientações alimentares (31,15%); e no cuidado comunitário, as ações de vigilância nutricional (39,89%). Observou-se maiores percentuais relativos à adesão insatisfatória de adolescentes às ações individuais (51,28%) e em grupo (53,57%). A adesão satisfatória foi mais prevalente no cuidado comunitário (81,58%). Não foi encontrada associação entre as ações ofertadas e a sua adesão. Diante da baixa adesão às ações, sugere-se melhorar a oferta de estratégias ativas e emancipatórias em grupos terapêuticos e na comunidade.
Human mobility and malaria risk in peri-urban and rural communities in the Peruvian Amazon
Authors: Gomez Joaquin , Grosso Alessandro , Guzman-Guzman Mitchel , Garcia Castillo Stefano , Castro Marcia C. , Torres Katherine , Vinetz Joseph M. , Gamboa Dionicia 
Published: January 2025

Background
While the global burden of malaria cases has decreased over the last two decades, the disease remains a major international threat, even on the rise in many regions. More than 85% of Peruvian malaria cases are in the Amazonian region of Loreto. Internal mobility primarily related to occupation is thought to be primarily responsible for maintaining endemicity and introducing and reintroducing malaria parasites into areas of anophelism, a challenge for malaria eradication. This study focuses on identifying the sources of malaria transmission and patterns of human mobility in order to understand the movement and transmission of the parasite.

Methods
The assessment of connectivity produced by human mobility was evaluated in three districts of Loreto, through 10 cross-sectional population screening from 2018 to 2020. We used social network analysis (SNA) to obtain weighted and unweighted degrees of connectivity and explore its variability by socio-demographic characteristics. In addition, we integrated travel history and malaria incidence data to estimate parasite connectivity due to internal human mobility between locations. Finally, we used logistic multivariate regressions to explore the factors associated with Plasmodium spp. infection in mobile individuals.

Results
We found that internal human mobility results in high connectivity between communities from the Mazan, Iquitos, and San Juan Bautista districts. We identified nearby destinations that may act as sinks or sources for malaria transmission, including densely populated towns and rural campsites. In addition, we found that being a male, traveling to rural campsites, and working outdoors are associated with Plasmodium spp. infection in travelers from the Mazan district.

Conclusions
We provide compelling evidence about how human mobility connects rural communities in the Peruvian Amazon. Using SNA, we uncovered district-specific patterns and destinations, providing further evidence of human mobility heterogeneity in the region. To address the challenge of human mobility and malaria in this setting, geographic heterogeneity of malaria transmission must be considered.
Cross-sectional study of lung cancer patients as a potential high-risk factor for abdominal aortic aneurysm
Authors: Gwon Hye Ran , Woo A La , Yong Seung Hyun , Park Young Mok , Kim Song Yee , Kim Eun Young , Jung Ji Ye , Kang Young Ae , Park Moo Suk , Kang Du–Young , Park Seong Yong , Lee Sang Hoon , Kwon Jun Seong 
Published: January 2025

Background
Abdominal aortic aneurysm (AAA) is more common in Non-small cell lung cancer (NSCLC) patients. Considering that ruptured AAA is potentially fatal, timely management of AAA would result in long-term survival benefits. We assess the prevalence and characteristics of AAA in resectable NSCLC patients who would benefit from AAA surveillance.

Methods
1,019 resectable NSCLC patients in Severance and Kangbuk Samsung Hospitals were reviewed from January 2019 to November 2020. The control group comprised 2,899 cancer-free people who had a health check-up CT scan in Severance between January 2018 and December 2019.

Results
Among resectable primary NSCLC patients, 39/1,019 (3.8%; odds ratio [OR], 19.19; 95% confidence interval [CI], 8.10–46.46) had AAA compared with 6/2,899 (0.2%) in the control (P<0.001). In multivariable regression analysis, male (OR, 13.24; 95% CI, 1.50–117.48; P = 0.020), aging (OR, 1.10; 95% CI, 1.04–1.15; P<0.001), current smoker (OR, 4.20; 95% CI, 1.20–14.62; P = 0.024), and coronary artery disease (OR, 3.13; 95% CI, 1.48–6.62; P = 0.003) were independent risk factors for AAA in NSCLC.

Conclusion
The present study found that the incidence of AAA in resectable early-stage lung cancer patients was significantly higher than in the cancer-free control group. Therefore, we suggest that early-stage NSCLC patients, especially smokers older than 60 years, undergo regular AAA surveillance as part of their lung cancer monitoring.
Effect of the COVID-19 pandemic on colorectal cancer screening in two university-affiliated health care systems
Authors: Kumar Vinod , Golzarri-Arroyo Lilian , Roth Sarah , Imperiale Thomas F. 
Published: January 2025

Objectives
In two large university affiliated healthcare systems, we examined trends in colorectal cancer (CRC) screening both prior to and during the COVID-19 pandemic to compare the trends in non-invasive screening tests and colonoscopy.

Materials and methods
In this retrospective time-trend analysis, we obtained the numbers of colonoscopies and non-invasive tests performed monthly during the pandemic and the year prior to it. We obtained colonoscopy data from five endoscopy units with the indication determined by dual independent review. Monthly numbers of completed fecal immunochemical (FIT) and FIT-DNA tests were obtained from the electronic medical records of both health systems. Trends in testing, numbers, and stage of incident CRCs diagnosed during the 30-month interval were examined using Poisson regression and logistic regression, respectively.

Results
From January 2019 to June 2021, we identified 16,939 FIT tests, 2,942 FIT-DNA tests, and 38,332 colonoscopies from the two health systems, and 368 colorectal cancers (105 early stage, 263 advanced stage) from the private hospital system. Overall colonoscopy volume declined by 18.7% (from 16,483 to 13,393) in 2020 compared to 2019 in both health systems, returning to baseline in 2021. Non-invasive tests declined by 21.9% in 2020, but increased in 2021 due to greater use of FIT/DNA. Compared to 2019, incident CRCs declined in 2020 but rebounded in 2021, with no difference in early versus late-stage cancers.

Conclusions
These trends in CRC screening tests may be useful for modeling the effects of the pandemic on the longer-term outcomes of CRC incidence and mortality.
Challenges and requirements of AI-based waste water treatment systems
Authors: Dalibard Antoine , Kriem Lukas Simon , Beckett Marc , Scherle Stephan , Yeh Yen-Cheng , Schließmann Ursula 
Published: January 2025

Abstract
Artificial Intelligence (AI) has emerged as a promising tool for enhancing the efficiency, accuracy, and sustainability of water treatment systems. However, integrating AI into water treatment comes with its own set of challenges, and specific requirements must be met to fully utilize the potential of these techniques. This study delves into the complexities associated with implementing AI in waste water treatment (WWT) and the necessary prerequisites for developing effective AI-based solutions. The most commonly utilized AI techniques in WWT applications fall under the umbrella of supervised Machine Learning (ML). Supervised ML models serve as excellent tools (correlation coefficient >0,8) for modeling, predicting, and optimizing WWT processes. They have a wide range of applications, including data cleansing, system design, control optimization and predictive maintenance. ML models are particularly useful in optimizing process parameters with significant energy savings achievable (up to 30 % reported in literature). The main challenges for the implementation of such models in WWT are: quality data availability, efficient data management along the data chain and the choice of appropriate ML models. These challenges are highlighted with two concrete examples in the field of water reuse for microalgae cultivation and predictive maintenance of cooling towers. These examples showcase the diverse range of potential use cases for AI and machine learning, especially in wastewater applications.
Concept study of an autonomous aerial mobile network relay for pre-hospital emergency care
Authors: Gruner Jonas , Wembers Carlos Castelar , Plattenteich Tavia , Pflughaupt Jasper , Zhavzharov Ievgen , Schildbach Georg , Rostalski Philipp 
Published: January 2025

Abstract
This paper presents a prototype for an aerial mobile network relay in the setting of pre-hospital emergency care. The requirements for such an unmanned aerial vehicle (UAV) are summarized and used to develop a hardware prototype. Gaussian processes and Bayesian optimization are implemented to find an optimal location for the aerial relay. The aerial relay enhances the network throughput by a factor of up to 7.2 in comparison to a relay on the ground. The findings show that UAV-based relays have the potential to play a vital role in emergency rescue.
An untargeted metabolomics approach to evaluate enzymatically deconjugated steroids and intact steroid conjugates in urine as diagnostic biomarkers for adrenal tumors
Authors: Vogg Nora , North Eleanor , Gessner Arne , Fels Felix , Heinrich Markus R. , Kroiss Matthias , Kurlbaum Max , Fassnacht Martin , Fromm Martin F. 
Published: January 2025

Abstract

Objectives
Urinary steroid profiling after hydrolysis of conjugates is an emerging tool to differentiate aggressive adrenocortical carcinomas (ACC) from benign adrenocortical adenomas (ACA). However, the shortcomings of deconjugation are the lack of standardized and fully validated hydrolysis protocols and the loss of information about the originally conjugated form of the steroids. This study aimed to evaluate the quality of the deconjugation process and investigate novel diagnostic biomarkers in urine without enzymatic hydrolysis.

Methods
24 h urine samples from 40 patients with ACC and 40 patients with ACA were analyzed by untargeted metabolomics using liquid chromatography-high-resolution mass spectrometry both unmodified and after hydrolysis with arylsulfatase/glucuronidase from Helix pomatia. Both approaches were compared regarding the differentiation of ACC vs. ACA via ROC analyses and to evaluate the hydrolyzation efficiency of steroid conjugates.

Results
Steroid glucuronides were fully deconjugated, while some disulfates and all monosulfates were still largely detectable after enzymatic hydrolysis, suggesting incomplete and variable deconjugation. In unhydrolyzed urine, steroid monosulfates showed the best differentiation between ACC and ACA (highest AUC=0.983 for C21H32O6S, followed by its isomer and two isomers with the molecular formula C21H32O7S). Moreover, several disulfates were highly abundant and increased in ACC compared to ACA.

Conclusions
This work highlights the limitations of hydrolyzing steroid conjugates before analysis and shows a possible superiority of a direct analysis approach compared to a hydrolysis approach from a methodological point of view and regarding diagnostic accuracy. Several steroid conjugates were found as promising diagnostic biomarkers for differentiation between ACC and ACA.
Acrodermatitis dysmetabolica: lessons from two pediatric cases
Authors: Kahraman Ayça Burcu , Cosar Meryem Sıla , Dogan Ekrem Eren , Ünlü Yaşar , Ugur Cuneyt , Bagcı Zafer 
Published: January 2025

Abstract

Objectives
Acrodermatitis dysmetabolica (AD) is a dermatologic manifestation associated with inherited metabolic disorders (IMDs), distinct from acrodermatitis enteropathica, which occurs solely due to zinc deficiency.

Case presentation
This report presents two pediatric cases: a 30-month-old girl with maple syrup urine disease (MSUD) experiencing AD secondary to severe isoleucine deficiency due to a protein-restricted diet, showing improvement with dietary adjustments, and a 2.5-month-old boy infant with propionic acidemia (PA) who developed AD alongside septic shock, which progressed despite intervention.

Conclusions
These cases emphasize the importance of identifying AD in IMDs and the critical need for meticulous monitoring of amino acid levels, as deficiencies may lead to severe complications.
Adrenal gland size in fetuses with congenital heart disease
Authors: Oberste Kathleen M. , Willy Daniela , de Santis Chiara , Möllers Mareike , Schmitz Ralf , Oelmeier Kathrin 
Published: January 2025

Abstract

Objectives
The aim of this study was to compare the adrenal gland size of fetuses with congenital heart diseases (CHD) and normal fetuses.

Methods
In this cross-sectional prospective study we measured the fetal adrenal gland size (total width, cortex width, medulla width, adrenal gland ratio of total width divided by medulla width) in 62 fetuses with CHD and 62 gestational-age-matched controls between 20 + 0 and 39 + 3 weeks of gestation. First, we clustered three CHD subgroups: CHD group_1 with a normal outflow tract (n=7), CHD group_2 with an altered outflow tract and anterograde flow in the ascending aorta (n=39) and CHD group_3 with an altered outflow tract and retrograde flow in the ascending aorta (n=16). In a second step, we summed up all CHD cases with outflow tract anomalies to CHD group_2 + 3 (n=55). Each group was compared to their matched controls.

Results
Prenatally, fetuses affected by CHD with outflow tract alterations show an elevated adrenal gland ratio (total width/medulla width) compared to normal fetuses (p<0.001). This finding applies to both subgroups of outflow tract alterations with anterograde (p<0.001) and retrograde perfusion of the ascending aorta (p<0.001).

Conclusions
Fetuses affected by CHD with an altered outflow tract show a relatively larger cortex of the adrenal gland compared to normal fetuses. The results of this study suggest that haemodynamic changes during fetal maturation cause an elevated metabolic stress level that may be responsible for an enlarged adrenal gland ratio.
European football player valuation: integrating financial models and network theory
Authors: Cohen Albert , Risk Jimmy 
Published: January 2025

Abstract
This paper presents a new framework for player valuation in European football, by fusing principles from financial mathematics and network theory. The valuation model leverages a “passing matrix” to encapsulate player interactions on the field, utilizing centrality measures to quantify individual influence. Unlike traditional approaches, such as regressing on past performance-salary data, this model focuses on in-game performance as a player’s contributions evolve over time. Consequently, our model provides a dynamic and individualized framework for ascertaining a player’s fair market value. The methodology is empirically validated through a case study in European football, employing real-world match and financial data. This cross-disciplinary mechanism for player valuation adapts the effect of connecting pay with performance, first seen in Scully ((1974). Pay and performance in major league baseball. Am. Econ. Rev. 64: 915–930), to include in-game contributions as well as expected present valuation of stochastic variables.
The role of gestures in logic
Authors: Reichenberger Andrea , Lemanski Jens , Bhattacharjee Reetu 
Published: January 2025

Abstract
Gestures are usually regarded as a casual element of communication processes between logicians. By contrast, we aim to show that gestures have played a significant role in logic. We argue that the development of communication techniques and their standardization have led to the rise of formal notation systems commonly used in logic today. In order to substantiate this claim, the historical development of the use of gestures in (early) modern logic is investigated. This investigation uncovers exemplary communication and proof techniques that illustrate the efficacy of gestures as representational media in formal logic. Revisiting the tradition of gestures in logic offers promising paths and insights for today’s logic as a communication practice in the digital age.
Deep-subwavelength engineering of stealthy hyperuniformity
Authors: Park Jusung , Park Seungkyun , Kim Kyuho , Kwak Jeonghun , Yu Sunkyu , Park Namkyoo 
Published: January 2025

Abstract
Light behaviours in disordered materials have been of research interest primarily at length scales beyond or comparable to the wavelength of light, because order and disorder are often believed to be almost indistinguishable in the subwavelength regime according to effective medium theory (EMT). However, it was demonstrated that the breakdown of EMT occurs even at deep-subwavelength scales when interface phenomena, such as the Goos–Hänchen effect, dominate light flows. Here we develop the engineering of disordered multilayers at deep-subwavelength scales to achieve angle-selective manipulation of wave localization. To examine the disorder-dependent EMT breakdown, we classify the intermediate regime of microstructural phases between deep-subwavelength crystals and uncorrelated disorder through the concept of stealthy hyperuniformity (SHU). We devise material phase transitions from SHU to uncorrelated disorder for distinct angular responses of wave localization by tailoring the short-range and long-range order in SHU multilayers. The result paves the way to the realization of deep-subwavelength disordered metamaterials, bridging the fields of disordered photonics and metamaterials.
The Deer Cult and the Origin of Normativity in the Upper Paleolithic Religion
Authors: Rauer Constantin 
Published: January 2025

Abstract
The empirical data for an analysis of normativity in the origin of religion can be found on the one hand (since the late Middle Paleolithic) in the burials and their symbolism and on the other hand (in a more pronounced form since the Upper Paleolithic) in the religious pictorial stories of cave painting and mobile art. In principle, three forms of normativity can be distinguished. First, there are commandments and prohibitions concerning representation itself: who may be buried and who may not, what is to be depicted and what is not. Secondly, there is a rule of language of representative contents: the burials and their grave goods follow precise rules of staging (grave form, posture and orientation, symbolic language of the grave goods). The same applies to cave painting and mobile art, whose typification reveals a grammar of rules. Finally, the symbolic forms of representation can also be considered as laws for the real individual and social behaviour of people. Thus the pictorial stories of cave paintings and mobile art can be understood as a policy that regulates the moral principles of hunting ethics, cult ethics, sexual ethics and social ethics. Burials also have a normative influence on reality by defining the anthropological image of mankind. Especially on the basis of the stag symbolism this paper will attempt to establish a classification of the different areas and different forms of late Middle and Upper Paleolithic religious normativities in order to explore their structural grammatology – the rule behind the sets of rules – of this normativity. Since this is a constitution of the genealogy of normativity it might present new perceptions for the Conditio humana.
Perioperative D-dimer levels and head and neck cancer surgery: a prospective observational study
Authors: Yalçıner Başak , Koçak Özge Nur , Yalçıner Gökhan , Büyükkoç Onur , Çelik Burak , Bal Ceylan , Babademez Mehmet Ali 
Published: January 2025

Abstract

Objectives
D-dimer molecules are formed as a result of fibrinolysis and elevation of D-dimer levels are suggestive for thrombosis. The elevation of D-dimer levels and its correspondence with thromboembolism in orthopedic and general surgeries are well studied, but there are only a few studies in literature that investigates this issue in head and neck surgery. We aimed to investigate D-dimer levels and its course throughout the perioperative period in patients who underwent head and neck cancer surgery.

Methods
We conducted a prospective, observational study in patients who underwent neck dissection along with primary tumor resection in our otorhinolaryngology clinic between January 2022 and June 2023. D-dimer levels were measured from blood samples preoperatively and postoperatively days 0–7 and on postoperative 14th day. D-dimer levels were compared statistically.

Results
Twenty-one patients were included in the study. D-dimer values peaked on the first day then gradually decreased and reached a level slightly below 2 times of the preoperative values on the 14th day. The change in D-dimer levels between preoperative and postoperative days 1–14 was statistically significant. The difference between D-dimer levels measured on each day of the first week and levels on 14th day was found to be significant. Also, difference of D-Dimer levels between postoperative day 0 and day 7 was statistically significant.

Conclusions
The trend of D-Dimer levels following surgery in head and neck cancer patients may prove useful in clinical practice to rule out thrombotic events, in accordance with other risk factors and symptomatology.
PRÁTICAS ECOLÓGICAS TRADICIONAIS: ONTEM E HOJE
Authors: Woortmann Ellen Fensterseifer 
Published: January 2025

Aula Magna do Curso de Bacharelado em AntropologiaData: 29 de março de 2011Horário: 19h30Local: Auditório da FAUrb - Rua Benjamim Constant, 1359, Pelotas, RS.Profª Drª Ellen Fensterseifer Woortmann (UnB)Tema: "Práticas Ecológicas Tradicionais - ontem e hoje"A professora Ellen Woortmann, natural do Rio Grande do Sul, doutorou-se em Antropologia pela Universidade de Brasília, instituição em que viria a exercer as funções de coordenadora do Programa de Pós-Graduação em Antropologia, chefe do Departamento de Antropologia e diretora do Instituto de Ciências Sociais. Atualmente aposentada, coordena o Grupo de Pesquisa do CNPq "Memória e Patrimônio Alimentar: tradição e modernidade". A antropóloga Ellen Woortmann apresenta uma longa trajetória de pesquisas e, dela resultante, uma vasta obra, que há muito exerce influência na Antropologia brasileira e nos estudos rurais. Ela exerce, atualmente, a vice-presidência da Associação Brasileira de Antropologia.Link do vídeo: https://vimeo.com/99538774Senha de acesso: LEPPAIS