bluuebunny/crossref_metadata_2025_split huggingface dataset:
Balade au pays des « Merles moqueurs » : regards sur une génération désenchantée dans La Novela de mi vida (2002), de Leonardo Padura Fuentes
Authors: Parisot Fabrice 
Published: October 2022

Cet article s’attache à rendre compte, dans le roman La novela de mi vida (2002), de l’évolution, au long d’une trentaine d’années, d’un groupe de jeunes écrivains cubains (appelés les « Merles moqueurs ») confrontés aussi bien au dirigisme culturel mis en place au début des années 70 par un régime réputé autoritaire qu’aux graves répercussions économiques et psychologiques qu’ils subissent dues à la crise du début des années 90 lors de la « Période spéciale en temps de paix » après l’effondrement du bloc soviétique. La vision que propose le romancier Leonardo Padura Fuentes de cette génération est celle d’une génération totalement désenchantée et la représentation qu’il donne à lire de Cuba à travers La Havane est celle d’un pays en pleine dégénérescence.
Alessandria Biobank: storia, implementazione, nuovi scenari
Authors: Bonvicini Paolo , Libener Roberta , Amore Valentina , Oliveri Giulia , Maconi Antonio 
Published: October 2022

Una biobanca, in termini generali, viene descritta come una struttura volta alla collezione, gestione, conservazione e distribuzione di biomateriali e dati ad essi correlati a fini di ricerca genetica.
Il termine biobancaggio si riferisce dunque ad una serie di attività svolte dalle biobanche che differiscono per natura, obiettivi, business models, risultati e impatto sociale, politico e scientifico. Data l’interazione tra biomateriale e dati associati, le biobanche rappresentano un ponte tra l’evoluzione della medicina personalizzata e la preservazione e il miglioramento delle condizioni della salute pubblica, alla luce del ruolo che svolgono nel permettere, appunto, la conservazione di un significativo numero sia di biomateriali che di dati correlati, necessari per l’avanzamento della ricerca biomedica.
Presso l’Infrastruttura Ricerca Formazione e Innovazione dell’Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo è inserito il “Centro Raccolta Materiale Biologico” (CRMB) che comprende la collezione del mesotelioma maligno (BB-MM), istituita fin dal 2005, la collezione del carcinoma mammario, istituita nel 2021, e il Biorepository, istituito già nel 2016 per garantire elevati livelli di qualità e sicurezza in ambito di stoccaggio e conservazione dei campioni biologici previsti da protocolli di studi clinici e/o destinati ad attività di ricerca.
Si configura come un’unità di servizio finalizzata alla raccolta, conservazione e distribuzione dei campioni biologici a scopo di ricerca scientifica, garantendo i diritti dei soggetti coinvolti.
Il presente studio si prefigge, in linea con l’evidenza fornita dalla letteratura scientifica di settore e il suo contributo, di descrivere la storia del biobanking e, parallelamente, l’evoluzione di Alessandria Biobank, tra istituzionalizzazione e risultati raggiunti, per incrementare la conoscenza della biobanca e del suo operato.
Use of Intraoperative Coronary Angiography to Guide Surgical Intervention in Coronary Artery Bypass Graft Surgery
Authors: Mueller Jaclyn H. , Hollander Kimberly 
Published: October 2022

ABSTRACT
Following coronary artery bypass graft surgery, graft patency is a major factor contributing to patient morbidity and mortality. There are several modalities available for assessing graft patency intra-op used by both the anesthesiologist and surgeon. However, these modalities have their own advantages and disadvantages which will be summarized in this case report. As illustrated by this case, angiography continues to be the gold standard for coronary anatomy assessment and can be performed easily using a portable digital fluoroscopic system.
A Retrospective Analysis of the Incidence, Outcome and Factors Associated with the Occurrence of Euglycemic Ketoacidosis in Diabetic Patients on Sodium Glucose Co-Transporter – 2 Inhibitors Undergoing Cardiac Surgery
Authors: Murugesan Karthik Babu , Balakrishnan Soundravalli , Arul Anandhi , Ramalingam Srinivasan , Srinivasan Muralidharan 
Published: October 2022

ABSTRACT

Introduction:
SGLT2i is a new class of drugs used for type 2 diabetes. SGLT2i are known to cause EuKA in the perioperative period. Euglycemic ketoacidosis (EuKA) can cause life-threatening metabolic acidosis in the perioperative setting. Though the event rate of SGLT2i associated diabetic ketoacidosis in nonoperative setting is low, incidence among peri-operative patients can be very high and remains unknown.

Aim:
The aim of this study was to find the incidence, analyze outcome, and establish correlation between risk factors and EuKA in cardiac surgical patients on SGLT2i.

Materials and Methods:
This is a retrospective study analyzing 24 cardiac surgical patients who were on SGLT2i for type 2 diabetes mellitus. Data collection included age, sex, BMI, preoperative HbA1C, albumin, creatinine, type of SGLT2i and timing of stopping before surgery, insulin administration in the immediate pre-operative period; use of CPB, GI infusion and inotropes in the intraoperative period; blood ketone, duration of ventilation, hydration status and length of postoperative stay in postoperative period. Patients were diagnosed to have EuKA if any one of the serially measured postoperative ketone values was more than 0.6 mmol/L (ketone positive). The collected data were used to find an association between the risk factors and the occurrence of EuKA.

Results:
Of the 24 patients, 17 patients developed EuKA. (70.8.%). 10 of the 17 EuKA in our study required preoperative Insulin for diabetic control whereas none in the ketone negative patients required insulin. This was statistically significant (P = 0.019). Association of other factors to EuKA were not statistically significant.

Conclusion:
Though the event rate of SGLT2i associated Diabetic ketoacidosis in nonoperative setting is low, (17), the occurrence of EUKA in cardiac surgical patients on SGLT2i in our study was 70.8% (17 out of 24 patients). Patients who require insulin in addition to other oral hypoglycemic drugs for immediate preoperative glycemic control are at risk for the development of SGLT2 inhibitor-induced EuKA postoperatively. Missing the diagnosis of EuKA is fatal in these patients. We couldn't make a diagnosis in our first patient whom we lost. Since it was diagnosed in all our study patients by measuring serial ketone values, there was no mortality and insignificant morbidity. Cessation of SGLT2i before surgery, expectant watch for blood ketones, and treatment with GI infusion reduce morbidity and mortality in cardiac surgical patients.
Impact of a One-Day Three-Dimensional Transesophageal Echocardiography Workshop on Clinical Practice at a Single Academic Centre
Authors: Menon Priya R , Meineri Massimiliano , Ender Jörg , Forner Anna Flo 
Published: October 2022

ABSTRACT

Background:
Transesophageal echocardiography (TEE) is a powerful diagnostic tool which has become an integral part in the management of cardiac surgery patients. We developed a one-day 3D TEE workshop specifically designed to meet the needs of perioperative cardiac anaesthesiologists. We hypothesized that participation in the workshop would increase the uptake of 3D TEE in routine perioperative practice.

Aims:
To examine the impact of one-day 3D TEE workshop on 3D TEE image acquisition and incorporation into routine perioperative practice.

Setting:
Tertiary care hospital.

Design:
Prospective observational monocentric study.

Subjects and Methods:
A convenience sample of 20 cardiac anesthesiologists (with an option to attend the one- day workshop midway through the study) from a single center consented to have their intraoperative TEE images collected during the course of the study reviewed for research purposes. Images acquired 6 months before, immediately after, and 6 months following the workshop and images were examined by a blinded, expert echocardiographer.

Results:
Data collected for 16 participants (8 workshop attendees, 8 non-attendees) indicate that the TEE workshop increased the number of 3D TEE images, but not x images acquired immediately following the workshop (P=0.006). No difference was observed in number of 3D images at six months' post workshop. Workshop participants obtained more 3D and multi-plane images after the workshop and more 3D images at 6 months compared to those who did not attend the workshop.

Conclusion:
Our study suggests that a single day hands-on 3D TEE workshop may have had an impact on the implementation of intraoperative 3D TEE in experienced echocardiographers.
Incidence and Severity of Postoperative Complications in Patients Undergoing Surgery Following COVID-19 Infection at a Tertiary Care Center in South India
Authors: Abraham Annu Susan , Sasikumar Niranjan Kumar , Rajan Sunil , Abubaker Reema , Manoharan Kruthika Sree , Kumar Lakshmi 
Published: October 2022

Background:
The occurrence of postoperative pulmonary complications (PPCs) and other sequelae of COVID-19 infections like thromboembolic events in patients coming for surgery following COVID-19 infection in the Indian population had not been adequately studied.

Aim of the Study:
We evaluated the incidence of PPCs, acute kidney injury, and thromboembolic complications such as pulmonary embolism, deep-vein thrombosis, myocardial infarction, stroke, and 30-day mortality rate in post-COVID-19 patients undergoing surgery compared to those without a history of COVID-19 infection.

Settings and Design:
It was a retrospective, observational, case–control study conducted in a tertiary care center.

Materials and Methods:
One hundred and sixty-six post-COVID-19 surgical patients were included. A matched control group (n = 166) was formed by choosing patients with no history of COVID-19 who underwent similar surgical procedures under a similar technique of anesthesia. Their medical records were analyzed for the development of postoperative pulmonary and nonpulmonary complications and 30-day mortality.

Statistical Analysis Used:
Independent samples t-test and Chi-squared test were used for statistical analysis.

Results:
The mean age of patients in the control group was significantly higher than those in the post-COVID-19 group. The number of patients who received two doses of vaccine was also significantly higher in the control group. Comparison of the distribution of preexisting medical conditions and postoperative complications, duration of hospital stay, and incidence of 30-day mortality did not show any significant difference in both groups.

Conclusion:
Incidence of postoperative complications, length of hospital stay, and 30-day mortality in post-COVID-19 patients undergoing surgical procedures were comparable with patients with no history of COVID-19 infection.
Comparative Study between Intrathecal 0.5% Isobaric Levobupivacaine, 0.5% isObaric Ropivacaine, and 0.5% Hyperbaric Bupivacaine in Elective Lower Segment Cesarean Section
Authors: Oraon Priyanka , Hembrom Boniface , Kumar Mukesh , Ram Barun , Lakra Ladhu 
Published: October 2022

Background:
Neuraxial anesthesia in obstetrics began with the spinal block by Oskar Kreis in 1900. The technique of subarachnoid blockade has been refined since then and various drugs have been used to provide analgesia and anesthesia for infraumbilical surgeries.

Materials and Methods:
This study was conducted because of newer options available, such as an intrathecal drug with appropriate sensory and motor blockade and minimal haemodynamic changes that can be used in the lower segment cesarean section safely. Ninety patients were randomly divided into three groups including 30 patients in each group. Group B, Group L, and Group R, each receiving 2.2 mL of 0.5% hyperbaric bupivacaine, 0.5% isobaric levobupivacaine, and 0.5% isobaric ropivacaine, respectively. All groups were compared concerning sensory block, motor block, hemodynamic stability, and complications if any.

Results:
The onset of sensory block at T8, two-segment regression time from the highest block, time of regression to L1, total duration of analgesia, onset and total duration of motor block were comparable between Group B and L (P > 0.05), but both these groups were statistically significant with Group R (P < 0.05). Hypotension was observed among all the groups; however, the incidence was minimum in Group R.

Conclusion:
12 mg of isobaric ropivacaine and 12 mg of isobaric levobupivacaine, compared to 12 mg hyperbaric bupivacaine (2.2 mL of 0.5% each), when administered intrathecally provides adequate anesthesia for cesarean section. The lesser duration of motor block in ropivacaine compared to the other two drugs could be beneficial for early ambulation, also the incidence of hypotension was lower in Group R.
Assessment of Intraoperative Hemodynamics and Recovery Characteristics in Pediatric Patients Receiving Buprenorphine and Propofol Anesthesia for Cleft Palate Surgery
Authors: Lakra Prabha Rashmi , Thaware Pooja , Bharati  
Published: October 2022

Background:
Children with cleft palate are usually operated on before 18 months of age. Cleft palate surgery demands stable hemodynamic parameters, a bloodless surgical field, and an awake and pain-free child after surgery.

Aims:
We aimed to study the anesthesia technique using buprenorphine and propofol for cleft palate surgery.

Settings and Design:
The design involves prospective observational study. The study was conducted at a tertiary care hospital.

Materials and Methods:
After the Institutional Ethics Committee approval, 42 patients aged 6 months to 12 years undergoing cleft palate surgery were enrolled. Anesthesia induction commenced with sevoflurane or propofol 3 mg.kg−1. After intubation, buprenorphine 3 μg.kg−1 was given, and propofol infusion was started at 2–8 mg.kg−1.h−1. Hemodynamic parameters, awakening time, and surgeon's satisfaction score were noted. After extubation, pain score, emergence agitation (EA) score, sedation score, recovery score, and adverse events were noted.

Statistical Analysis:
All statistical analyses were performed using the 20.0 version of the Statistical Package for the Social Science (SPSS) software program. Continuous data were summarized as mean and standard deviation, and were analyzed using a two-sided Student's unpaired t-test. Categorical data were represented using frequencies and proportions.

Results:
The single dose of buprenorphine with propofol infusion started immediately postintubation causes a significant decrease in heart rate after 1 h. This contributed to a favorable operative field, increasing the surgeon's satisfaction score. In the recovery room, patients were essentially pain-free till 2.5 h after surgery, with only one patient requiring rescue analgesia. Furthermore, 90% of patients showed a smooth and calm recovery with no EA. The Steward's recovery score remained high throughout without any complication.

Conclusions:
In cleft palate surgeries, a single-dose buprenorphine 3 μg.kg−1 and propofol maintenance infusion 2–8 mg.kg−1.h−1 were effective in maintaining hemodynamic parameters and a bloodless surgical field and managing postoperative pain with a good recovery profile.
Clinical characteristics and risk factors for mortality of hospitalized cancer patients with COVID-2019 in Mecca, Saudi Arabia
Authors: Ghaleb Nabil , Bulkhi Adeeb , Al-Qurashi Eid , Touman Abdelfattah , Aldobyany Ahmad , Alsaggaf Rajaa Z. , Mabar Hanan , Murtaza Noureen H. , Rajab Ammar 
Published: October 2022

BACKGROUND:
Cancer patients are particularly vulnerable during the coronavirus disease 2019 (COVID-19) pandemic. This study aimed to evaluate clinical characteristics and mortality among cancer patients with COVID-19.

METHODS:
This retrospective, observational cohort study included 53 patients with a malignancy and reverse-transcription polymerase chain reaction-confirmed severe acute respiratory syndrome coronavirus-2 infection in a tertiary care center in Mecca, Saudi Arabia, from March 14, 2020, to October 29, 2020. Clinical, laboratory, and radiological data were collected from institutional electronic records and analyzed.

RESULTS:
Overall, 53 patients (62% male) were enrolled. The mean age of the patients was 54.9 ± 19.0 years, with 76% aged <65 years. The most common symptoms were fever (66%), dry cough (40%), and dyspnea (36%). Most infections (89%) were community acquired. Hematological malignancies (36%) were the most common cancer type. The most common solid tumors were breast cancer (23%) and colon cancer (9%). Just over half (51%) had a stage 4 tumor, and 30% of the patients had received chemotherapy within 2 weeks before the onset of COVID-19 symptoms. Initial chest radiographs showed pneumonia in 43% of patients; 38%, 9%, and 6% required oxygen support, intensive care unit admission, and invasive mechanical ventilation, respectively. The most common complication was secondary bacterial infection (13.2%). The all-cause mortality rate was 17%. In the multivariable logistic regression, dyspnea, leukocytosis, use of systemic steroids, and secondary bacterial infection were found to be risk factors for death.

CONCLUSION:
Hospitalized cancer patients with COVID-19 have a high mortality rate. Our study finds a correlation between multiple independent risk factors and mortality. Patients with dyspnea, leukocytosis, systemic steroid use, or secondary bacterial infection require more care, attention, and possibly more aggressive treatment.
Scanning Electron Microscopy of the Inner and Outer Aspects of Tiger Tail Hairs
Authors: de Almeida Hiram Larangeira , Pinto Joice Brião Göebel , de Almeida Antônia Larangeira , de Castro Luis Antonio Suita , Ruas Caroline Pires 
Published: October 2022

Background:
Tiger tail hairs, Morse hairs or pili annulati is a nonsyndromic hair shaft disorder, characterized by alternating light and dark bands along the hair shaft.

Methods:
The outer surface and the inner structure of longitudinally cut tiger tail hairs were examined with scanning electron microscopy.

Results:
Hair specimens of five affected individuals showed small surface undulations with “curtain-like” folding of the hair cuticula (microcanaliculi). In the inner surface cord-like linear structures with serpiginous, tortuous traject were seen, associated with some cavities.

Conclusions:
These findings suggest that this condition is due to some deficient protein synthesis/arrangement, not only due to cavities in the hair cortex. The term Tiger tail hair is a descriptive clinical term of little scientific rigor. This disorder has been reported mainly as pili annulati; however, rings are not observed. In analogy to pili canaliculi, in which well-formed grooving is observed in the hair surface, we suggest the term pili microcanaliculi to describe this condition, based in the ultrastructural findings.
Effectiveness of telemedicine in increasing the self – efficacy of patients with gestational trophoblastic neoplasia at a Tertiary Hospital in Davao City
Authors: Tapodoc Jannah A. , Lasala Lynnette L. 
Published: October 2022

BACKGROUND:
Telemedicine has the potential of bridging the gap and achieving equity in receiving healthcare services. The department of health encouraged telemedicine using cell phones or consultations through social media platforms to decongest hospitals and reduce possible exposure to COVID-19.

OBJECTIVES:
This study aimed to describe the effectiveness of telemedicine in increasing the self-efficacy of patients with gestational trophoblastic neoplasia (GTN) in a tertiary hospital in Davao City.

MATERIALS AND METHODS:
This research was a mixed method pre-post-test exploratory design with two main phases: a quantitative phase of assessing the effectiveness of telemedicine in increasing self-efficacy to patients with GTN using Strategies Used by People to Promote Health-29, and a qualitative phase of online focus group discussions of patients and health-care workers. Thematic analysis was applied to contextualize the experience of the participants in engaging in telemedicine in the delivery of medical services.

RESULTS:
Total subscale of self-efficacy of the patients during the first consultation was high. The respondents had a high level of confidence in stress reduction and in making decisions. The respondents had a very high positive attitude. After 6 months of telemedicine, the total subscale of self-efficacy was very high. The respondents had a high level of confidence in stress reduction and very high levels of confidence in making decision and positive attitude. The respondents had improved self-efficacy and verbalized that telemedicine was easy and readily accessible.

CONCLUSION:
Telemedicine helped the respondents improve their self-efficacy. There was a significant difference between the baseline stress reduction and making decisions subscales after 6 months of utilizing telemedicine.
Teachers’ Curriculum Knowledge in Teaching Christian Religious Studies among Senior High Schools of the Greater Accra Region of Ghana
Authors: Mensah Eric , Owusu Martin 
Published: October 2022

The study sought to investigate on teachers’ curriculum knowledge in teaching Christian Religious Studies among Senior High Schools of the Greater Accra Region of Ghana. The population of the study was CRS teachers in Senior high schools in the Greater Accra Region of Ghana. Through census sampling approach, all teachers of CRS were involved in filling the questionnaire. Analysis of data was done through descriptive statistics. The study established that teachers of CRS had high knowledge about the rationale of teaching CRS. It was also found that teachers of CRS had high knowledge of the aims of teaching CRS. It is therefore recommended that Universities that are mandated to train teachers of CRS in Ghana should include courses like curriculum studies in CRS emphasis, the rationale (philosophy and logic) and aims for the subject. This would ensure that teachers who teach CRS have adequate knowledge and the rationale and aims for teaching the subject. The Ghana Education Service (GES) in collaboration with the National Council for Curriculum and Assessment (NaCCA) should organise regular in-service trainings for the teachers of CRS.
Faculty Perceptions of Self-efficacy in Remote Teaching during COVID-19 Pandemic Lockdown in a Selected University in Sub-Saharan Africa
Authors: Gude Korso 
Published: October 2022

The major purpose of this study was to establish the faculty perceptions of self-efficacy in remote teaching during COVID-19 Pandemic lockdown in a selected University in Sub-Saharan Africa. A quantitative survey method was used to collect data, analyse, and interpret results. The modified 24-items, 5 point Likert Teachers’ Self-Efficacy Scale (TSES) developed by Tschannen-Moran and Woolfolk Hoy (as cited in Butucha, 2010) was used to gather data. It consisted of possible responses ranging from 1 = nothing to 5 = a great deal. Participants were 69 male (68.3%) and 32 female (31.7%) faculty members drown from a total of 145 across all schools in the selected university. The survey instrument assessed self-efficacy in three areas; instructional strategies, classroom management and student engagement. Data was gathered immediately after the faculty had completed their remote teaching and administered the final examinations online while still in the CIOVID-19 pandemic Lockdown. Since all faculty members were in the lockdown, online survey was sent out to them in google forms. Using excel for Windows version 10, a statistical analysis of the data was done. Descriptive statistics such as frequency, percentage, mean and standard deviation were generated to answer the research question. Results revealed that the faculty believed that they can do quite a bit in student engagement (M=4.03, SD=0.81), instructional strategies (M=3.98, SD=0.80) and classroom management (M=3.93, SD =0.79), in teaching remotely during the COVID 19 lockdown. The study recommends that since technology use in the classroom is now inevitable, the faculty should make intentional efforts to move from doing quite a bit to a great deal in online instructional strategies, classroom management and student engagement.