bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biopsia con sistema de aspiración al vacío guiada por tomosíntesis
Authors: Bustamante Liliana , Falcón Liana , Hammond Rowena , Pastor Dayana , Cuiza Elizabeth , Bayona Soledad , Cruzado Lisett , Gamero Paola , Castro Cecilia 
Published: September 2022

La biopsia mamaria es un procedimiento ambulatorio, mínimamente invasivo, que evita una cirugía para el diagnóstico, y permite la planificación correcta del tratamiento con la potencial disminución del número de cirugías. De acuerdo al método de imágenes que se vea mejor la lesión a biopsiar, estos procedimientos se pueden realizar bajo guía ecográfica y mamográfica (estereotáxica/tomosíntesis).
La biopsia guiada por tomosíntesis ha reemplazado a la biopsia por estereotaxia, ya que con esta tecnología además se puede acceder a las lesiones detectadas sólo en la mamografía 3D-tomosíntesis, que son principalmente lesiones no calcificadas. Gracias al uso más frecuente de la mamografía 3D-tomosíntesis, como estudio complementario a la mamografía 2D, se ha incrementado la tasa de detección del cáncer de mama, que muchas veces se presentan como lesiones ocultas en la mamografía convencional, y que antes de la llegada de la biopsia guiada por tomosíntesis, las pacientes eras sometidas a una resonancia magnética para posibilidad de biopsia guiada por ese método o, finalmente, se realizaban cirugías de diagnóstico, generando mayor costo y retraso en el tratamiento.
La biopsia guiada por tomosíntesis permite realizar el procedimiento más simplificado, con menor dosis de radiación y en un menor tiempo en comparación con la biopsia por estereotaxia, mejorando el confort de la paciente y el flujo de trabajo.
En esta revisión se conocerá la tecnología de la biopsia con sistema al vacío bajo guía 3D-tomosíntesis, sus beneficios, y su aplicación para el diagnóstico oportuno del cáncer de mama.
Accidente ofídico: análisis del abordaje terapéutico en una entidad de salud privada de Lima, Perú
Authors: Cruz Meza Cinthia , Laguna-Torres Victor Alberto 
Published: September 2022

Los accidentes por mordedura de serpiente son un problema de salud pública en países tropicales y subtropicales. En el Perú la mayoría de estos eventos ocurren en la selva, sin embargo, también se reportan en ciudades costeras. Lima, es una ciudad en un valle de costa en medio del desierto, donde no es usual atender accidentes ofídicos y menos aún en la emergencia de una entidad de salud privada. La mayoría de las muertes y consecuencias graves por mordedura de serpiente son prevenibles, en la medida que se logre disponibilidad y accesibilidad de antídotos seguros y eficaces. Se presenta el caso de un paciente de 39 años quien sufrió un accidente por mordedura de serpiente en el Departamento de Lima.
La comunicación rápida y eficaz con los diferentes estamentos involucrados nos ayudó a enfrentar adecuadamente este caso. Presentamos este texto para afianzar conocimientos y encontrar oportunidades de mejora de un problema real y que puede ser mortal sin manejo adecuado.
Papilomatosis múltiple de la mama. A propósito de un caso
Authors: Pinto Paz Mirian E. , Carrasco Collantes Marcia , Hammond Castro Rowena , Guerra Miller Henry 
Published: September 2022

Se presenta el caso de una paciente que acude al Servicio de Cirugía Oncológica de Mamas, por presentar un pequeño tumor palpable en mama derecha asociado a telorrea. En los exámenes diagnósticos de mamografía, ecografía mamaria y resonancia magnética, se evidenciaron múltiples lesiones nodulares en mama derecha asociados a ectasia ductal que comprometían gran parte del tejido glandular. En la mama izquierda se encontró una lesión única, sospechosa de malignidad. El diagnóstico clínico y por imágenes fue de papilomatosis múltiple, hallazgos que fueron confirmados mediante biopsias percutáneas de los nódulos más representativos en mama derecha y de la lesión única de mama izquierda. La importancia de presentar este caso es porque la papilomatosis múltiple es una patología infrecuente, considerada como lesión de alto riesgo, con posibilidad de estar asociada a neoplasia maligna o a malignizarse en el tiempo, no habiendo un consenso definido para su manejo y seguimiento.
Lutrinae Bonaparte, 1838 (Carnivora, Mustelidae) from the Plio-Pleistocene of the Lower Omo Valley, southwestern Ethiopia: systematics and new insights into the paleoecology and paleobiogeography of the Turkana otters
Authors: GROHÉ Camille , UNO Kevin , BOISSERIE Jean-Renaud 
Published: September 2022

We describe otter remains (Lutrinae Bonaparte, 1838) from the Plio-Pleistocene of the Lower Omo Valley of southwestern Ethiopia. We report isolated lower and upper teeth of Torolutra sp. dated to c. 3.3 Ma, dental specimens and a femur of Enhydriodon Falconer, 1868, attributed to a new species, dated between c. 3.4 Ma and 2.5 Ma, as well as a humerus of Lutrinae indet. dated between c. 1.9 Ma and 1.8 Ma. The new species Enhydriodon omoensis n. sp. is the largest species of the genus discovered so far. It is even larger than its close relative E. dikikae Geraads, Alemseged, Bobe & Reed, 2011, a Pliocene lion-sized otter from the Afar region and potentially from eastern Turkana. Based on stable oxygen and carbon isotope analyses, we found that Enhydriodon from the Lower Omo Valley could have been terrestrial and fed on both aquatic and terrestrial prey, acquired by either hunting or scavenging. It filled a unique ecological niche in the past communities co-existing with australopithecines. Enhydriodon and Torolutra Petter, Pickford & Howell, 1991 went extinct in Africa around the Plio-Pleistocene transition, along with many large-sized and ecologically specialized carnivorans. This extinction event could be linked to the many geological, climate, and biotic changes occurring in the eastern African rift during this period, notably the incursion of early hominins into the carnivore guild.
The first documented record of Chvalaea Papp & Földvári, 2002 (Diptera, Hybotidae, Ocydromiinae) from the Australasian Region: a new species and its possible relationship to other members of the genus
Authors: Barros Luana Machado , Soares Matheus Mickael Mota , De Freitas-Silva Rafael Augusto Pinheiro , Ale-Rocha Rosaly 
Published: September 2022

Chvalaea australis sp. nov. is described and illustrated, representing the first species of Chvalaea Papp & Földvári, 2002 from the Australasian Region. A discussion of the geographic distribution and the possible relationship among the species of the genus is provided.
Nuevos hallazgos de carnivoros en el complejo de yacimientos mesopleistocenos de La Sierra de Atapuerca, Burgos.
Authors: Cervera José 
Published: September 2022

Se informa de nuevos hallazgos de restos de Carnivoros en el complejo de yacimientos de la Sierra de Atapuer­ca. Se aiiaden dos nuevos taxa: Cuon alpinus europaeus para Trinchera-Galeria y Lynx pardina spelaea para la Sima de los Huesos. Por otra parte se describen nuevos restos de Canis lupus spp. de Trinchera-Galeria y Panthera leo de ambos yacimientos.
Antibiotic resistance and genomic features of Clostridioides difficile in southwest China
Authors: Gu Wenpeng , Li Wenge , Jia Senquan , Zhou Yongming , Yin Jianwen , Wu Yuan , Fu Xiaoqing 
Published: September 2022

Background
Clostridioides difficile infection (CDI) caused by toxigenic strains leads to antibiotic-related diarrhea, colitis, or even fatal pseudomembranous enteritis. Previously, we conducted a cross-sectional study on prevalence of CDI in southwest China. However, the antibiotics resistance and characteristics of genomes of these isolates are still unknown.

Methods
Antibiotic susceptibility testing with E-test strips and whole genome sequence analysis were used to characterize the features of these C. difficile isolates.

Results
Forty-nine strains of C. difficile were used in this study. Five isolates were non-toxigenic and the rest carried toxigenic genes. We have previously reported that ST35/RT046, ST3/RT001 and ST3/RT009 were the mostly distributed genotypes of strains in the children group. In this study, all the C. difficile isolates were sensitive to metronidazole, meropenem, amoxicillin/clavulanic acid and vancomycin. Most of the strains were resistant to erythromycin, gentamicin and clindamycin. The annotated resistant genes, such as macB, vanRA, vanRG, vanRM, arlR, and efrB were mostly identified related to macrolide, glycopeptide, and fluoroquinolone resistance. Interestingly, 77.55% of the strains were considered as multi-drug resistant (MDR). Phylogenetic analysis based on core genome of bacteria revealed all the strains were divided into clade 1 and clade 4. The characteristics of genome diversity for clade 1 could be found. None of the isolates showed 18-bp deletion of tcdC as RT027 strain as described before, and polymorphism of tcdB showed a high degree of conservation than tcdA gene.

Conclusions
Most of the C. difficile isolates in this study were resistant to macrolide and aminoglycoside antibiotics. Moreover, the MDR strains were commonly found. All the isolates belonged to clade 1 and clade 4 according to phylogenetic analysis of bacterial genome, and highly genomic diversity of clade 1 was identified for these strains.
Determination of Genetic Divergence Pattern of White Fly Resistant Cotton Cultivars by Using Microsatellite
Authors: Hussain Syed Bilal , Yousaf Tayyaba , Zubair Muhammad 
Published: September 2022

Cotton is considered a cash crop in the agriculture sector, and whitefly infestation is one of the cotton crop's significant biotic stresses. This study aimed to identify whitefly Bemisia tabaci resistant cotton varieties that can be incorporated into a cotton breeding program to improve the cotton crop's quality, yield, and growth. In this study, we used 10 Microsatellite (SSR) markers for genetic diversity assessment among 50 genotypes of G. hirsutum. 58 loci were found by applying the NAU and BNL series primers. A maximum number of loci, eight, were amplified by SSR markers NAU-883, NAU-2714, and BNL-827, respectively. SSR marker JESPER-101 amplified a minimum number of the loci,i.e., 2. The PIC count ranged from 0.7215 to 0.8828, with a mean value of 0.4034. NAU 2161 displayed a maximum polymorphism value of 0.8828 and BNL 1672 showed a minimum polymorphism value of 0.4034. Cluster analysis grouped the 50 genotypes into four clusters. Cluster A holds 30 varieties. Cluster B includes 11 varieties. Cluster C had six varieties, and cluster D had 3. Genetic diversity is maximum in varieties NS-161, VH-307, and AGC-555, as they are located at the most significant distance in clusters. The SSR genetic profile for every cultivar made it conceivable to separate a few cultivars.
To conclude, this investigation of the genetic divergence of cotton cultivars with SSR markers supports the need to bring new alleles into the genetic pool of the cultivars. It can help in assessing the best whitefly-resistant cotton variety. The information generated from diversity analysis studies will help in future breeding plans for improving the hereditary variety of cotton cultivars to fulfill the need for cotton development for various purposes.
Potential Use of Ipil-Ipil (Leucaena leucocephala Lam.) As Fish Feed Ingredient: A Mini-review
Authors: Haetami Kiki , Abun . , Shafa Bellarisa Rahma 
Published: September 2022

Aims: This article aims examines the effect of giving Ipil-Ipil (Leucaena leucocephala) in feed on the growth of various types of fish and the nutritional content of Ipil-Ipil.
The method used in this literature study is to review several research articles on the use of Ipil-Ipil on fish growth, and the nutritional content of various parts plant.
The utilization of Ipil-ipil raw materials for fish is limited by the present of some antinutrient substances such as phytic acid, mimosine, tannins, as well as a fairly the high content of neutral detergent fiber (NDF) of 39.5% and acid detergent fiber (ADF) of 35.10%. Studies evaluating the nutritional quality of Leucaena as a fish feed ingredient gave varying results. There are significant differences with using Leucaena leucocephala as a substitute food for fish feed. It shows an increase in performance from the point of view of a certain growth rate, weight gain and feed conversion ratio. However, not all dietary experiments are affected for fish growth due to the processing techniques applied that involve soaking and drying the leaves thus reducing the antinutrients in Leucaena leaf meal which are mostly mimosine.
Conclusion: The leaves of Leucaena leucocephala have the potential to make considerable contributions to feeding of the Africa catfish as this study demonstrate the it’s suitability at 20% level of inclusion without any negative effects on the growth.
A Study under Sodic Soil Condition for Estimation of Correlation and Path Coefficient Analysis of Rice (Oryza sativa L.) Yield and Its Component Traits
Authors: Sharma Poonam , Vimal S. C. , Jha Neha , Debnath Ashim 
Published: September 2022

Effective selection necessitates knowledge of the nature and extent of population variation, character correlation with yield among individuals, and effect of environment on the assertion of these traits. Under timely seeded and irrigated conditions in sodic soil, this study used Augmented Block Design (ABD) to investigate correlations and path coefficients between yield and yield components in 85 germplasms, including four checks (Pusa sungandha-4, NDR-2065, sarjoo-52, Narendra usar-3). The correlation coefficient expresses the relationship between two variables, but it contains no information regarding cause and effect, such as which variable is dependent and which is independent. As a result, path-coefficient analysis must be utilized to examine the direct and indirect impact of numerous independent characters on a dependent character. The GYPP exhibited highly significant and positive correlations with BYPP and HI. When the genotypic correlation was assigned, it was discovered that characters like BYPP and HI had a positive direct impact on GYPP whereas characters DFF and DM were exhibited negative direct impact on GYPP. The most important indirect yield component was BYPP. As a result, these traits should be emphasized and further evaluated as a selection criterion for future rice improvement programmes in sodic soil.
A Ga Doped NiTiO3 Photocatalyst for Overall Water Splitting under Visible Light Illumination
Authors: Wang Long , Kong Yuehua , Fang Yuanxing , Cai Pingru , Lin Wei , Wang Xinchen 
Published: September 2022

AbstractPhotocatalytic overall water splitting (OWS) is an appealing strategy to convert solar energy and produce hydrogen fuel. NiTiO3 (NTO) is an earth‐abundant material, which is studied as a robust photocatalyst with broad absorptance of sunlight spectrum, ranging from ultraviolet to infrared regions. Herein, by a rational design of an NTO‐based photocatalytic system, the activity for photocatalytic OWS is realized under both ultraviolet and visible light illuminations, and H2 and O2 evolution is achieved within the stoichiometric ratio of 2:1. Specifically, Gallium is doped into the NTO crystal to activate the material for photocatalytic OWS by improving photoexcited charge migration. Meanwhile, Co and Pt species are screened out as the oxygen evolution and hydrogen evolution co‐catalysts, respectively. Theoretical stimulations, steady state experiments, and operando characterizations are acquired to investigate the OWS performance. This research paves the pathway to apply this small‐bandgap photocatalyst for OWS by maximizing the solar energy harvesting.
Simultaneously Enhancing Direct‐Current Density and Lifetime of Tribovotaic Nanogenerator via Interface Lubrication
Authors: Qiao Wenyan , Zhao Zhihao , Zhou Linglin , Liu Di , Li Shaoxin , Yang Peiyuan , Li Xinyuan , Liu Jiaqi , Wang Jie , Wang Zhong Lin 
Published: September 2022

AbstractTribovoltaic nanogenerators (TVNGs) present great properties such as high direct‐current density and continuous output performance, which has great potential to solve the power supply problem for miniaturized electronic devices. However, the severe wear problem of TVNG causes rapid attenuation of current density, which is difficult to realize long‐term operation with high output. In this work, an effective strategy via interface lubrication is proposed to enhance the direct‐current density and lifetime of TVNGs simultaneously. The water‐based graphene oxide solution is utilized as a lubricant, which can increase the sliding surface carriers to enhance current density, and reduce the wear between the copper and the silicon wafer surface due to its excellent lubrication performance. Hence, the TVNG can generate peak current density output ≈775 mA m−2, accompanied with 31 mC m−2 transfer charges density. The TVNG via interface lubrication can maintain high current output after 30 000 cycles. In addition, it can combine with triboelectric nanogenerator to constitute a dual‐type signal sensor, which can be used to monitor bridge vibration and goods’ weight. This study provides an effective method to solve the wear problem of TVNG and improve direct‐current density simultaneously, which will accelerate the practical application of TVNGs in the future.
Unveiling Charge Transport and Degradation Mechanisms of Aqueous Zn|α‐MoO3 Batteries in Conventional Concentration and Water‐in‐Salt Electrolytes: A Multi‐Modal In Situ and Operando Study
Authors: Dunkin Mikaela R. , Kuang Jason , Yan Shan , King Steven T. , Housel Lisa M. , Ma Lu , Ehrlich Steven N. , Okasinski John S. , Takeuchi Kenneth J. , Takeuchi Esther S. , Marschilok Amy C. , Wang Lei 
Published: September 2022

AbstractHerein charge storage and transport properties are elucidated and cell degradation mechanisms of rechargeable aqueous Zn|α‐MoO3 batteries in three electrolyte systems (3 m ZnSO4, 3 m ZnCl2, and 30 m ZnCl2 [12.5 m] water‐in‐salt (WIS)) are distinguished by a combination of in situ X‐ray diffraction (XRD), in situ X‐ray absorption spectroscopy (XAS), operando optoelectrochemistry, and operando energy dispersive X‐ray diffraction (EDXRD). In conventional concentration 3 m electrolytes, in situ XRD and XAS, as well as ex situ scanning transmission electron microscopy data collectively support Zn2+ as the primary charge carrier. In addition, these systems are susceptible to cathode dissolution, Zn corrosion coupled with the hydrogen evolution reaction, and the resultant formation of basic zinc salt phases. The multi‐modal in situ and operando experimental analyses validate facile H+ intercalation and extraction in concentrated 30 m ZnCl2 WIS electrolyte. Via operando EDXRD, reaction front and charge transport limitation during discharge and charge in the viscous WIS electrolyte are spatially tracked. This work provides new insight into the stability and degradation mechanisms of aqueous zinc batteries during static storage and upon dynamic cycling, and highlights the utility of in situ and operando techniques in understanding the superior stability of WIS electrolytes.
The potential for floral evolution in response to competing selection pressures following the loss of hawkmoth pollination in Ruellia humilis
Authors: Heywood John S. , Michalski Joseph S. , McCann Braden K. , Andres Kara J. , Hall Allison R. , Hartman Amber D. , Middleton Tessa C. , Chiles Amelia , Dewey Sarah E. , Miller Cay A. 
Published: September 2022

AbstractPremiseIn the absence of hawkmoth pollinators, chasmogamous (CH) flowers of Ruellia humilis self‐pollinate by two secondary mechanisms. Other floral visitors might exert selection on CH floral traits to restore outcrossing, but at the same time preferential predation of CH seeds generates selection to increase the allocation of resources to cleistogamous (CL) flowers.MethodsTo assess the potential for an evolutionary response to these competing selection pressures, we estimated additive genetic variances () and covariances for 14 reproductive traits and three fitness components in a Missouri population lacking hawkmoth pollinators.ResultsWe found significant for all 11 floral traits and two measures of resource allocation to CL flowers, indicating the potential for a short‐term response to selection on most reproductive traits. Selection generated by seed predators is predicted to increase the percentage of CL flowers by 0.24% per generation, and mean stigma–anther separation is predicted to decrease as a correlated response, increasing the fraction of plants that engage in prior selfing. However, the initial response to this selection is opposed by strong directional dominance.ConclusionsThe predicted evolutionary decrease in the number of CH flowers available for potential outcrossing, combined with the apparent preclusion of potential diurnal pollinators by the pollen‐harvesting activities of sweat bees, suggest that 100% cleistogamy is the likely outcome of evolution in the absence of hawkmoths. However, rare mutations with large effects, such as delaying budbreak until after sunrise, could provide pathways for the restoration of outcrossing that are not reachable by gradual quantitative‐genetic evolution.
Cutaneous squamous cell carcinoma in an autosomal‐recessive Adams–Oliver syndrome patient with a novel frameshift pathogenic variant in the EOGT gene
Authors: Lukas Meyer‐Landolt , Harald Gaspar , Sanz Javier , Trippel Mafalda , Sabina Gallati , Jochen Rössler 
Published: September 2022

AbstractAplasia cutis congenita (ACC) of the scalp and terminal transverse limb defects (TTLD) are the characteristic findings of Adams–Oliver syndrome (AOS). The variable clinical spectrum further includes cardiac, neurologic, renal, and ophthalmological findings. Associated genes in AOS are in the Notch and the CDC42/Rac1 signaling pathways. Both autosomal‐dominant and autosomal‐recessive inheritances have been reported, the latter with pathogenic variants in DOCK6 or EOGT. The EOGT‐associated recessive type of AOS has been postulated to present a more favorable prognosis. We here report a 12‐year‐old girl from a refugee family of Iraq with consanguineous parents. She was born with a severe phenotype of AOS presenting a large ACC of the scalp with an underlying skull defect, which was often infected and inflamed. Afterward, additional ulceration developed. Furthermore, the girl showed microcephaly, TTLD on both hands and feet, and neurological findings: spastic paresis, epilepsy and suspicion of intellectual deficit. Molecular genetic analysis (next‐generation sequencing) revealed a novel frameshift mutation in the EOGT gene in Exon 13 in homozygous constellation: c.1013dupA p.(Asn338Lysfs*24). A biopsy within an ulceration at the scalp ACC showed a cutaneous squamous cell carcinoma (cSCC) with local invasive growth into the dura, the meninges, and the cortex. Treatment including surgical resection and focal irradiation was not curative and the girl deceased 6 months after initial diagnosis. This report on a patient with AOS and an autosomal‐recessive EOGT gene variant dying of a local aggressive cSCC at an ACC lesion shows that close monitoring of ACC is essential.