bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sustainability science must challenge common sense: a response to Bodin (2021)
Authors: Isgren Ellinor , Longo Stefano B. 
Published: February 2022

AbstractIn this comment, we respond to the claim of (Bodin, Sustain Sci 16: 2151–2155, 2021) that sustainability science, as a research community, has begun to “lean to the left” in a problematic manner. On one hand, we remain unconvinced by the examples cited as indications for this tendency, and argue for caution in making such judgements. On the other hand, we hold that that there may be reasons for seemingly “left leaning” positions which are scientific rather than purely political or ideological. Finally, we urge sustainability scientists to take heed of social theorists’ insights regarding the pitfalls of common sense analysis. This can better enable open and reflexive debate on the field’s development as well as the challenges it seeks to address.
Discursive dynamics and lock-ins in socio-technical systems: an overview and a way forward
Authors: Simoens Machteld Catharina , Fuenfschilling Lea , Leipold Sina 
Published: February 2022

AbstractUnderstanding the dynamics of stability and change is key to accelerate sustainability transitions. This paper aims to advance and inspire sustainability transition research on this matter by collecting insights from interpretative environmental discourse literature. We develop a heuristic that identifies and describes core discursive elements and dynamics in a socio-technical system. In doing so, we show how the interplay of meta-, institutionalized, and alternative discourses, dominant, marginal, and radical narratives, as well as weak and strong discursive agency influence the socio-technical configuration. The heuristic suggests three discursive lock-ins reinforcing the stabilization of socio-technical systems: unchallenged values and assumptions, incumbents’ discursive agency, and narrative co-optation. Furthermore, it explores three pathways of discursive change: disruptive, dynamic and cross-sectoral. Overall, this paper puts forward a discursive perspective on sustainability transitions. It offers additional analytical approaches and concepts for discursive transition studies, elaborated insights on the dynamics within and between the analytical dimensions of a socio-technical system, as well as a theoretical baseline for analyzing discursive lock-in mechanisms and pathways of discursive change.
Humus horizon development during natural forest succession process in the Polish Carpathians
Authors: Sokołowska Justyna , Józefowska Agnieszka , Zaleski Tomasz 
Published: February 2022

AbstractAs a result of socio-economic changes and land abandonment, the main ecological driver of the Carpathian landscape is the progression of the natural forest succession process. Thus, aspects of this process have become worthy of attention, especially in the context of carbon sequestration and the management of protected areas. Soil processes, especially within the topsoil, are some of the most susceptible to change, due to the accumulation of organic matter during such land-use transformations. The purposes of this study were to investigate the differences in topsoil development using the A Horizon Development Index (ADI) and to study the composition of humic substances and advanced organic matter humification in different land-use areas in selected Carpathian national parks, i.e. Bieszczady, Magura and Pieniny National Parks in southern Poland. Additionally, a goal of this study was to compare the ADI and the spectroscopic coefficients of humic substances as indicators of the degree of humus horizon shaping as well as advanced organic matter humification. In total, ten transects were selected, each consisting of three different land-use areas: semi-natural meadow, successional forest and old-growth forest. Soil colour was determined in fresh and air-dried samples using the Munsell colour chart. In air-dried soil samples pH, soil texture, total organic carbon and total nitrogen were measured. Humic substances were extracted and further characterized by UV-VIS spectroscopy. The ADI confirmed the influence of natural forest succession on soil colour darkening and the development of the uppermost soil layer. Spectroscopic analyses of humic substances showed two different patterns depending on soil depth. In the 0–10 cm layer, natural forest succession reduced the rate of the humification process and decreased the degree of maturity of fulvic acids; in the 10–20 cm layer, it led to an increase in the rate of the humification process and a decrease in the content of humic and fulvic acids at the beginning of the transformation. The comparison of two different indicators of soil development — the ADI and the spectroscopic coefficients of humic substances (Q4/6,Q2/4,Q2/3, Δ logK) — indicated that these indexes are based on different features of soil and cannot be used interchangeably.
Overexpression of Programmed Cell Death 1 Prevents Doxorubicin-Induced Apoptosis Through Autophagy Induction in H9c2 Cardiomyocytes
Authors: Kanno Syu-ichi , Hara Akiyoshi 
Published: February 2022

AbstractDoxorubicin (DOX) is a potent chemotherapeutic agent; however, it causes severe heart injury via apoptosis induction in many patients. DOX-induced cardiotoxicity is attenuated by activated autophagy in the heart. We previously found that programmed cell death 1 (Pdcd1), an immune checkpoint receptor, inhibits DOX-induced cardiomyocyte apoptosis. In this study, we investigated whether autophagy contributes to the protective role of Pdcd1 against DOX-induced cardiomyocyte apoptosis. We also examined the role of Pdcd1 in DOX-induced apoptosis in cancer cells. Rat cardiomyocyte cell line H9c2 and human cancer cell lines K562 and MCF-7 were transfected with Pdcd1-encoding plasmid DNA to establish Pdcd1-overexpressing cells. Apoptosis and autophagy were determined using a luciferase assay. In H9c2 cells, DOX-induced apoptosis and viability reduction occurred through caspase activation. In particular, Pdcd1 overexpression activated the autophagy pathway through the inhibition of the mammalian target of rapamycin, a major negative regulator of autophagy. Moreover, it prevented DOX-induced cardiomyocyte apoptosis; a similar cardioprotection was observed when normal H9c2 cells (without Pdcd1 overexpression) were treated with rapamycin, an autophagy inducer, before the DOX treatment. Conversely, in cancer cells, Pdcd1 overexpression increased both basal and DOX-induced apoptosis. The role of Pdcd1 in DOX-induced apoptosis in cardiomyocytes and cancer cells was opposing. Pdcd1 signaling prevented DOX-induced apoptosis in cardiomyocytes, through autophagy induction; it enhanced DOX-induced apoptosis in cancer cells. Therefore, Pdcd1 could be a critical molecule for more effective and safer DOX chemotherapy.
Cross-Country and Gender Differences in Factors Associated with Population-Level Declines in Adolescent Life Satisfaction
Authors: Marquez Jose , Inchley Joanna , Long Emily 
Published: February 2022

AbstractAdolescent subjective well-being, including life satisfaction, has shown declines at national level across many countries in recent years. Although several possible explanatory factors have been identified, there is a lack of research on whether these may be similar or different across countries. Using data on 15-year-old adolescents from the Programme for International Student Assessment study in Scotland, England, Wales, Northern Ireland, the United States, Japan, Ireland and France in 2015 and 2018, we find that changes in school well-being and, to a lesser extent, the use of Information and Communication Technologies and material well-being were associated with observed declines in life satisfaction. Although there are similarities across some countries, cross-country differences in factors associated with decreasing life satisfaction emerged, notably between Western nations and Japan, with some gender differences also evident.
The role of industrial actors in the circular economy for critical raw materials: a framework with case studies across a range of industries
Authors: Cimprich Alexander , Young Steven B. , Schrijvers Dieuwertje , Ku Anthony Y. , Hagelüken Christian , Christmann Patrice , Eggert Roderick , Habib Komal , Hirohata Atsufumi , Hurd Alan J. , Lee Min-Ha , Peck David , Petavratzi Evi , Tercero Espinoza Luis A. , Wäger Patrick , Hool Alessandra 
Published: February 2022

Abstract
In this article, we explore concrete examples of circularity strategies for critical raw materials (CRMs) in commercial settings. We propose a company-level framework for systematically evaluating circularity strategies (e.g., material recycling, product reuse, and product or component lifetime extension) in specific applications of CRMs from the perspectives of specific industrial actors. This framework is applied in qualitative analyses—informed by relevant literature and expert consultation—of five case studies across a range of industries: (1) rhenium in high-pressure turbine components, (2) platinum group metals in industrial catalysts for chemical processing and oil refining, (3) rare earth permanent magnets in computer hard disk drives, (4) various CRMs in consumer electronics, and (5) helium in magnetic resonance imaging (MRI) machines. Drawing from these case studies, three broader observations can be made about company circularity strategies for CRMs. Firstly, there are multiple, partly competing motivations that influence the adoption of circularity strategies, including cost savings, supply security, and external stakeholder pressure. Secondly, business models and value-chain structure play a major role in the implementation of circularity strategies; business-to-business models appear to be more conducive to circularity than business-to-consumer models. Finally, it is important to distinguish between closed-loop circularity, in which material flows are contained within the “focal” actor’s system boundary, and open-loop circularity, in which material flows cross the system boundary, as the latter has limited potential for mitigating material criticality from the perspective of the focal actor.
Coordinating Centers as a Strategy for Accelerating Cancer Epidemiology Consortia: Best Practices
Authors: Trentham-Dietz Amy , Bird Jennifer E. , Gangnon Ronald E. , Lindberg Sara M. , Madison Tena , Malecki Kristen M. C. , Shull James D. , Vredeveld Claudia , Rolland Betsy 
Published: February 2022

Abstract
Purposeof Review
This review highlights six “best practices” for cancer epidemiology coordinating centers to facilitate the success of a research consortium.

Recent Findings
Evidence from emerging literature regarding the Science of Team Science suggests that coordinating centers can more effectively foster collaborative cancer epidemiology research in consortia by (1) establishing collaboration as a shared goal at the start, (2) providing scientific expertise complementary to the research sites that adapts over the course of the project, (3) enacting anti-racist and inclusive approaches in all consortium decisions and activities, (4) fostering early-stage investigator career development, (5) engaging stakeholders including cancer survivors as peers, and (6) delivering reliable logistical support and technology tools with planned process evaluation so that researchers can collaboratively focus on the science.

Summary
By drawing on the Science of Team Science, coordinating centers can accelerate research progress and increase the impact of cancer epidemiology consortia.
Terapia ormonale sostitutiva e osteoporosi postmenopausale
Authors: Lello Stefano , Scambia Giovanni , Capozzi Anna 
Published: February 2022

SommarioL’osteoporosi postmenopausale è un processo per il quale il tessuto osseo sviluppa una fragilità risultando più suscettibile alle fratture anche per traumi che solitamente non comporterebbero tali eventi. La carenza estrogenica è un punto fondamentale nella patogenesi dell’osteoporosi. La TOS rappresenta un trattamento di scelta nella prevenzione della osteoporosi e delle fratture correlate, soprattutto nei primi anni di postmenopausa.
A highly active and stable Sr2Fe1.5Mo0.5O6-δ-Ce0.8Sm0.2O1.95 ceramic fuel electrode for efficient hydrogen production via a steam electrolyzer without safe gas
Authors: Wang Yao , Liu Tong 
Published: February 2022

AbstractHigh temperature steam (H2O) electrolysis via a solid oxide electrolysis cell is an efficient way to produce hydrogen (H2) because of its high energy conversion efficiency as well as simple and green process, especially when the electrolysis process is combined with integrated gasification fuel cell technology or derived by renewable energy. However, about 60%–70% of the electricity input is consumed to overcome the large oxygen potential gradient but not for electrolysis to split H2O to produce H2 due to the addition of safe gas such as H2 in the fuel electrode. In this work, Sr2Fe1.5Mo0.5O6-δ-Ce0.8Sm0.2O1.95 (SFM-SDC) ceramic composite material has been developed as fuel electrode to avoid the use of safe gas, and the open circuit voltage (OCV) has been effectively lowered from 1030 to 78 mV when the feeding gas in the fuel electrode is shifted from 3%H2O–97%H2 to 3%H2O–97%N2, reasonably resulting in a significantly increased electrolysis efficiency. In addition, it is also demonstrated that the electrolysis current density is greatly enhanced by increasing the humidity in the fuel electrode and the working temperature. A considerable electrolysis current density of − 0.54 A/cm2 is obtained at 800 °C and 0.4 V for the symmetrical electrolyzer by exposing SFM-SDC fuel electrode to 23%H2O–77%N2, and durability test at 800 °C for 35 h demonstrates a relatively stable electrochemical performance for steam electrolysis under the same operation condition without safe gas and a constant electrolysis current density of − 0.060 A/cm2. Our findings achieved in this work indicate that SFM-SDC is a highly promising fuel electrode for steam electrolysis.
Knowledge resources and the acquisition of spinouts
Authors: Adams Pamela , Fontana Roberto , Malerba Franco 
Published: February 2022

AbstractIn high-technology industries, employee spinouts have increasingly been identified as attractive targets for acquisitions. Yet employee spinouts may originate from different knowledge contexts. This study adopts a resource base perspective to examine the impact of both the knowledge heritage and the product strategy of spinouts originating from different contexts (i.e. from the same industry or from a related downstream industry) on the potential to be acquired by firms in the same industry or in related industries. Our findings, based on data from the semiconductor industry and its related downstream industries, show that spinouts from firms in a focal industry represent appealing targets for a broad range of buyer firms from within the focal industry or from related, downstream industries, independent of their product strategy at entry. By contrast, spinouts from downstream, user industries that enter into an upstream industry, tend to appeal to a more limited set of buyers. Our study suggests that managers and academics should consider the acquisition of spinouts whose founders have origins in related industries as a channel to access critical knowledge from upstream or downstream contexts. Yet because many of the critical knowledge resources that spinouts possess are embodied in their founders, such acquisitions also require careful management of personnel decisions post-acquisition.
Intelligent Prediction of Cryptogenic Stroke Using Patent Foramen Ovale from TEE Imaging Data and Machine Learning Methods
Authors: Bai Jiao , Yang Jia , Song Wanwan , Liu Yumin , Xu Haibo , Liu Yang 
Published: February 2022

AbstractIn spite of the popularity of random forests (RF) as an efficient machine learning algorithm, methods for constructing the potential association for between patent foramen ovale (PFO) and cryptogenic stroke (CS) using this technique are still barely. For the vital regional study areas (atrial septum), RF was used to predict CS in patients with PFO using partial clinical data of patients and remotely sensed imaging examination data obtained from Tee imaging. We validated our method on a dataset of 151 consecutive patients with detected PFO at a large grade A hospital in China from November 2018 to December 2020, we obtained an area under the relative operating characteristic curve of 0.816, with 65% specificity at 73% sensitivity. The RF models accurately represented the relationship between the CS and remotely sensed predictor variables. Therein, maximum mobility, large right-to-left shunt during Valsalva maneuver, size of PFO in diastole and systole, and diastolic length of the tunnel present higher predictive value in CS. Our findings suggest that multi-Doppler sensor data by transesophageal echocardiography (TEE)-detected morphologic and functional characteristics of PFO may play important roles in the occurrence of CS. These results indicate that the established random forest model has the potential to predict CS in patients with PFO and great promise for application to clinical practice.
Clostridioides difficile infection following dental antibiotic prescriptions in a cohort of US veterans
Authors: Wilson Geneva M. , Evans Charlesnika T. , Fitzpatrick Margaret A. , Poggensee Linda , Gibson Gretchen , Jurasic M. Marianne , Echevarria Kelly , Suda Katie J. 
Published: February 2022

AbstractAmong 108 (0.05% of cohort) US veterans with a Clostridioides difficile infection (CDI) within 30 days of a dental antibiotic prescription, 80% of patients received guideline-discordant antibiotics. Half had chronic gastrointestinal illness potentially exacerbating their CDI risk. More efforts are needed to improve antibiotic stewardship.
EUCLIDEAN NUMBERS AND NUMEROSITIES
Authors: BENCI VIERI , LUPERI BAGLINI LORENZO 
Published: February 2022

AbstractSeveral different versions of the theory of numerosities have been introduced in the literature. Here, we unify these approaches in a consistent frame through the notion of set of labels, relating numerosities with the Kiesler field of Euclidean numbers. This approach allows us to easily introduce, by means of numerosities, ordinals and their natural operations, as well as the Lebesgue measure as a counting measure on the reals.
Measuring the value of data governance in agricultural investments: A case study
Authors: Whittard Damian , Ritchie Felix , Musker Ruthie , Rose Michael 
Published: February 2022

Summary
The study at hand measures the value of improving data governance and access in the Supporting Soil Health Interventions (SSHI) project in Ethiopia. We applied two separate but interlinked models, one qualitative and one quantitative, to create a new framework enhancing the traditional cost–benefit analysis. The qualitative analysis provided novel insights into the specific types of value and the mechanisms through which they are generated. These results underpinned the development of an innovative framework to measure this perceived value quantitatively. By combining the quantitative and qualitative framework, the study demonstrated that it is possible to generate plausible and credible quantitative estimates of both costs and benefits of data governance and access. While acknowledging that the estimates are only illustrative, the case study results suggested on a direct cost measure, at a particular point in time, the SSHI data governance activities yielded a negative return. However, indirect social and public benefits are rarely quantified, but this paper shows that relatively few “indirect” benefits (current but unmeasured, or measurable but in the future) are necessary to reverse that view, at least from the point of the economy more generally.
Necrotaboos and Political Afterlives in Social Justice Activism during Mexico's Day of the Dead
Authors: Ohlson Olof 
Published: February 2022

AbstractThis article shows how vulnerable communities use Mexico's Day of the Dead for social justice activism. Activists sustain what I call the ‘political afterlives’ of their victims through street altars and dark humour. I analyse this as a ‘necrosocial repertoire of contention’. The Day of the Dead can play an important role in human rights advocacy by insisting that the marginalised dead be honoured and cared for. However, disappeared people pose a challenge to Mexico's horizontal, or popular, ethics of commemoration and illustrate what I call ‘necrotaboos’, with new problems for the nation's inclusive spirit of commemorating the dead.
Limited influence of experimentally induced predation risk on granivory in a tropical forest
Authors: Granados Alys , Bernard Henry , Brodie Jedediah F. 
Published: February 2022

AbstractSeed predation by rodents can strongly influence plant recruitment and establishment. The extent to which predation risk indirectly alters plant survival in tropical forests via impacts on granivory is unclear, making it difficult to assess the cascading impacts of widespread predator loss on tree recruitment and species composition. Experimental field studies that manipulate predation risk can help address these knowledge gaps and reveal whether antipredator responses among small mammals influence plant survival. We used camera traps and seed predation experiments to test the effects of perceived predation risk (via predator urine gel) on foraging behaviour of and seed removal by murid rodents in an unlogged and unhunted rainforest in Malaysian Borneo. We also explored the influence of seed traits (e.g., seed size) on removal by granivores and assessed whether granivore preferences for particular species were affected by predator urine. Murid visits to seed plots were positively related to overall seed removal, but were not affected by predator scent. Granivory was the lowest for the largest-seeded (>6 g) plant in our study, but was not influenced by predation risk. Predator urine significantly affected removal of one seed taxon (Dimoocarpus, ∼0.8 g), suggesting that removal by granivores may be affected by predation risk for some seed species but not others. This could have implications for plant species composition but may not affect the overall level of granivory.
A method for estimating the number of collision candidates in two waterways – for all intersection angles
Authors: Kaneko Fujio 
Published: February 2022

AbstractEstimating the collision frequency of ships (F) is important for assessing collision risk on waterways. To date, F has been estimated as the product of the number of collision candidates $({N_{a }})$ and the causation probability $({P_c})$: $F = {N_{a}} \cdot {P_c}$, where ${N_{a }}$ represents the number of collisions that occur when related ships continue on course with no intervention, and ${P_c}$ is the probability that collision avoidance fails. Fujii developed a general method and Pedersen formulated it to estimate ${N_{a }}$ in an intersectional area. Their method is generally called ‘the geometric method’ because collision candidates are estimated only from the geometric relationship between two ships. The method has been used in many projects to estimate F in waterways; however, its use should be limited to intersection angles ranging from 10° to 170°. This paper presents a method, statistically verified by computer simulation, that can be used at all intersection angles to overcome this limitation. Moreover, it demonstrates strong agreement with Pedersen's method at intersection angles of 10° to 170°.