bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of social media technologies on environmental collaboration and green innovation: a mediation–moderation model
Authors: Syed Muzzammil Wasim , Song Huaming , Junaid Muhammad 
Published: November 2022

PurposeDrawing upon information processing theory (IPT) and natural resource-based view (NRBV), this study analyses the role of social media technologies (SMT) on internal and external environmental collaboration and green innovation (green product, process and managerial innovation).Design/methodology/approachThis study took in-depth empirical research by developing a survey questionnaire to identify the relationship between SMTs, environmental collaboration and green innovation. The respondents of the questionnaire were supply chain professionals working in the manufacturing industry of Pakistan. The survey collected 475 responses, which were tested through PLS-SEM using Smart-PLS.FindingsThe study results indicate that SMTs positively influence both internal and external environmental collaboration. Furthermore, internal environmental collaboration (IEC) fosters green products and green managerial innovation. In contrast, external environmental collaboration (EEC) fosters green processes and green managerial innovation. This study has also tested the mediation of IEC and EEC, which shows that both IEC and EEC mediate all the relationships except green process and green product innovation. The results also revealed that innovation capabilities moderate the relationship between environmental collaboration and green innovation.Research limitations/implicationsThough this study has various practical implications, it is not free of limitations. First, the data were collected from Pakistan, and the results may only be compared with other developing countries. Second, few social media platforms have been considered, but they are increasing in numbers and could be used in upcoming studies. Third, green innovation in the context of products, processes and management is considered, but the concept is evolving, and its other indicators can be taken in upcoming studies.Practical implicationsThis study addresses the implication of SMTs, environmental collaboration, innovation capabilities and green innovation, which are helpful for managers and policymakers to design policies.Originality/valueThis study provides the seminal operationalization of SMTs in environmental collaboration and green innovation. This study emphasizes innovation capabilities that firms should adopt.
Clinical characteristics, management, and quality of life of psoriasis patients with coexistent lupus erythematosus: Data from the Malaysian Psoriasis Registry
Authors: Gan Teck Sheng , Ghazali Nurul Izyan , Voo Sook Yee Michelle , Low Dyoi‐E , Tang Jyh Jong , Kiing Jiu Wen , Muniandy Pubalan , Tey Kwee Eng , Wong Kit Wan , Mohamad Norazura , Tan Wooi Chiang , Selvarajah Latha , Ramalingam Rajalingam , Ng Fei Yin , Lee Choon Sian , Raja Teeba , Abdul Rahim Nazatul Shima , Tang Min Moon , Robinson Suganthy ,   The Malaysian Psoriasis Registry Working Group
Published: November 2022

AbstractObjectiveTo describe the clinical characteristics, management and quality of life of psoriasis patients with and without coexistent lupus erythematosus (LE).MethodsThis retrospective cross‐sectional study uses data from the Malaysian Psoriasis Registry (MPR) from January 2007 to December 2018.ResultsOf 21 735 psoriasis patients, 34 (0.16%) had coexistent LE. The male to female ratio among psoriasis patients with coexistent LE was 1:5.8 versus 1.3:1 in patients with psoriasis but without LE. Nearly 70% presented with LE preceding psoriasis. Psoriasis patients with LE had an earlier age of psoriasis onset (27.56 ± 11.51 versus 33.31 ± 16.94 years, P = 0.006), a higher rate of psoriatic arthropathy (26.5% versus 13.0%, P = 0.02), and a significantly greater impairment of quality of life (Dermatology Quality of Life Index >10; 57.6% versus 40.3%, P = 0.04) compared with psoriasis patients without LE. The majority (87.5%) had systemic LE. The incidences of lupus nephritis (72.7% versus 40%) and hematological abnormalities (50% versus 20%) were higher among patients with LE preceding psoriasis compared with those with psoriasis preceding LE. Antinuclear antibody and double‐stranded DNA were positive in 59.4% and 28.1% of psoriasis patients with LE, respectively. Hydroxychloroquine triggered the onset of psoriasis in 7 (24.1%) patients. Patients with LE were more likely to receive systemic treatment for psoriasis compared with those without LE (30.3% versus 14.2%, P = 0.008).ConclusionsPsoriasis patients with coexistent LE were uncommon, displayed a female preponderance, were more likely to have joint involvement, and had greater quality of life impairment than those without LE. LE preceded psoriasis in most of these patients, and systemic LE was the most common subtype.
Analysing individual 3D tree structure using the R package ITSMe
Authors: Terryn Louise , Calders Kim , Åkerblom Markku , Bartholomeus Harm , Disney Mathias , Levick Shaun , Origo Niall , Raumonen Pasi , Verbeeck Hans 
Published: November 2022

Abstract

Detailed 3D quantification of tree structure plays a crucial role in understanding tree‐ and plot‐level biophysical processes. Light detection and ranging (LiDAR) has led to a revolution in tree structural measurements and its 3D data are increasingly becoming publicly available. Yet, calculating structural metrics from LiDAR data can often be complex and time‐consuming and potentially requires expert knowledge.

We present the R package Individual Tree Structural Metrics (ITSMe), a toolbox that works with LiDAR tree point clouds and quantitative structure models (QSMs) derived from LiDAR point clouds to obtain individual tree structural metrics. It serves as a robust synthesis framework for researchers who want to readily obtain structural information from 3D data of individual trees.

The package includes functions to determine basic structural metrics (tree height, diameter at breast height, diameter above buttresses, projected crown area, 3D alpha crown volume) from individual tree point clouds, as well as more complex structural metrics (individual tree component volumes, branch angle‐, radius‐ and length‐related metrics) from QSMs.

The ITSMe package is an open‐source package hosted on GitHub that will make the use of 3D data more straightforward and transparent for a range of end‐users interested in exploiting tree structure information.
Lower fractal dimension of retinal vessel for patients with Birdshot chorioretinopathy
Authors: Furnon Lucas , Labarere José , Trucco Emanuele , Hogg Stephen , MacGillivray Tom , Chiquet Christophe 
Published: November 2022

AbstractPurposeTo identify the retinal vessel vasculature parameters associated with birdshot chorioretinopathy (BSCR).MethodsThis retrospective observational study included 28 prevalent cases of BSCR with a median time from diagnosis of 6 years and 28 controls matched for age, arterial hypertension, diabetes and refraction. Forty‐five‐degree fundus images of both dilated eyes were acquired with a fundus camera (Canon CR‐2, Tokyo, Japan). The summary diameter of the arterial retinal vessels (central retinal artery equivalent, CRAE), venous retinal vessels (central retinal vein equivalent, CRVE), vascular tortuosity and fractal dimension (FD) were measured using VAMPIRE software. Retinal vasculitis was characterized using fluorescein angiography and active choroiditis using indocyanine green angiography.ResultsAt baseline, BSCR was associated with lower FD compared with matched controls (mean difference, −0.04; 95% confidence interval [CI], −0.06 to −0.02, p < 0.001). No other VAMPIRE parameters (CRAE, CRVE, arterial and venous tortuosity) differed. Among BSCR patients, retinal vein vasculitis was associated with higher CRAE (mean difference, 21 μ; 95% CI, 2.6–40, p = 0.03), venous tortuosity (geometric mean ratio, 1.79; 95% CI, 1.18–2.72, p = 0.007) and FD (mean difference, −0.04; 95% CI, −0.06 to −0.01, p = 0.007). Resolution of retinal vein vasculitis during follow‐up was paralleled by decrease in CRAE, CRVE and venous tortuosity values and increase in venous FD, respectively.ConclusionBSCR is associated with lower FD value, suggesting that chronic retinal inflammation induces microvascular remodelling. Efficient treatment of retinal vasculitis may reverse changes in retinal vascular parameters. Changes in retinal vascular parameters could be potentially useful for assessing patients with BSCR disease.
Vigorous physical activity provides protection against all‐cause deaths among adults patients with nonalcoholic fatty liver disease (NAFLD)
Authors: Henry Austin , Paik James M. , Austin Patrick , Eberly Katherine Elizabeth , Golabi Pegah , Younossi Issah , Henry Linda , Gerber Lynn , Younossi Zobair M. 
Published: November 2022

SummaryBackgroundMortality benefits of vigorous leisure time physical activity (LTPA) among adults with NAFLD is not known.AimTo investigate association between LTPA and reduction in all‐cause mortality among adults with NAFLD.MethodsWe used NHANES (1999–2006) self‐reported PA data for adults (≥40 years) with mortality follow‐up through December 31, 2015. US‐Fatty Liver Index in absence of secondary causes identified NAFLD. Moderate and vigorous LTPA were calculated by the 2018 PA Guidelines for Americans.ResultsNAFLD prevalence among 5211 adults (46.2% male; 75.8% white; mean age 53.2 years) was 32.7%. Adults with NAFLD were less likely to report the recommended minimal PA (≥ 150 min/week, 55.5% vs 64.8%) or highly active PA (≥300 min/week, 39.2% vs 48.5%) compared to adults without NAFLD. Over a median follow‐up of 12.3 years, 355 deaths among adults with NAFLD and 510 deaths among adults without NAFLD were registered. In the metabolic comorbidities‐adjusted model, adults with NAFLD who reported ≥50% of their total PA as vigorous activity had a 56% reduction in all‐cause mortality risk (HR:0.44, 95%CI: 0.25–0.76) and cancer‐specific mortality risk (HR: 0.21, 0.06–0.66) but not cardiac‐specific mortality (p > 0.05) compared to adults with NAFLD who did not report any LTPA. This association remained significant even among adults with NAFLD who met the recommended minimal PA, among adults with NAFLD who reported any LTPA, and among adults with NAFLD who had metabolic abnormalities and in sensitivity analysis.ConclusionsEngaging in vigorous activity is beneficial for adults with NAFLD ‐ especially those with metabolic abnormalities.
Occupation as a measure of life course socioeconomic position and the risk of oral cancers in India
Authors: Alli Babatunde Y. , Durán Doris , Madathil Sreenath A. , Nicolau Belinda 
Published: November 2022

AbstractObjectivesEvidence suggests that different indicators of socioeconomic position (SEP) contribute to oral cancer risk. Occupational status, as a measure of SEP, may be able to capture aspects of social hierarchy in societies in which employment is highly correlated with other social structures such as caste systems. Often in such societies, the life course of an individual is also influenced by this hierarchy. However, the influence of life course occupational status on the risk of oral cancer is not well understood. This study aims to identify the life course model that is best supported by the data using life course SEP—as represented by occupation—on oral cancer risk in a population in the South of India.MethodsData from the HeNCe Life study, Indian site were used. Incident oral cancer cases (N = 350) were recruited from two major referral hospitals in Kozhikode, Kerala, South India, from 2008 to 2012. Controls (N = 371), frequency‐matched by age (5 years) and sex were recruited from the outpatient clinics at the same hospitals as the cases. Life grid‐based structured interviews collected information on an array of exposures throughout the life course of the participant. Occupation was coded with the 1988 International Standard Classification of Occupations, transformed to the simplified European Socioeconomic Classification, and further dichotomized into advantageous and disadvantageous SEP at three different life periods (childhood, early adulthood and late adulthood). The analysis was conducted using the Bayesian relevant life course exposure model with a Dirichlet noninformative prior and a weakly informative Cauchy prior to the overall lifetime effect and confounders.ResultsParticipants in disadvantaged SEP throughout their life had 3.6 times higher risk of oral cancer than those in advantaged SEP (OR = 3.6; 95% CrI = 1.6–7.2), after adjusting for potential confounders. While the crude and sex‐ and age‐adjusted models showed a clear childhood sensitive period for this risk, the model further adjusted for behavioural factors could not distinguish the specific life course period best explained by data.ConclusionOccupation status alone could provide a similar overarching risk estimate for oral cancer to those obtained from more complex measures of SEP.
Prolonged breastfeeding, sugar consumption and dental caries at 2 years of age: A birth cohort study
Authors: Abanto Jenny , Maruyama Jessica Mayumi , Pinheiro Emanuella , Matijasevich Alicia , Antunes José L. F. , Bönecker Marcelo , Cardoso Marly A. ,   the MINA‐Brazil Study Group
Published: November 2022

AbstractObjectivesPrevious cohort studies have found a positive association between prolonged breastfeeding (≥12 months) on dental caries, but few of them analysed the mediated effect of sugar consumption on this association. This study investigated whether prolonged breastfeeding is a risk factor for caries at 2‐year follow‐up assessment (21–27 months of age) and whether this effect is mediated by sugar consumption.MethodsA birth cohort study was performed in the Brazilian Amazon (n = 800). Dental caries was assessed using the dmf‐t index. Prolonged breastfeeding was the main exposure. Data on baseline covariables and sugar consumption at follow‐up visits were analysed. We estimated the OR for total causal effect (TCE) and natural indirect effect (NIE) of prolonged breastfeeding on dental caries using the G‐formula.ResultsThe prevalence of caries was 22.8% (95% CI: 19.8%–25.8%). Children who were breastfed for 12–23 months (TCE = 1.13, 95% CI: 1.05–1.20) and for ≥24 months (TCE = 1.27, 95% CI: 1.14–1.40) presented a higher risk of caries at age of 2 years than those breastfed <12 months. However, this risk was slightly mediated by a decreased frequency of sugar consumption at age of 2 years only for breastfeeding from 12 to 23 months (NIE; OR = 0.95, 95% CI: 0.91–0.97).ConclusionsIn this study, the effect of prolonged breastfeeding on the increased risk of dental caries was slightly mediated by sugar consumption. Early feeding practices for caries prevention and promoting breastfeeding while avoiding sugar consumption should be targeted in the first 2 years of life.
Carbachol increases locus coeruleus activation by targeting noradrenergic neurons, inhibitory interneurons and inhibitory synaptic transmission
Authors: Kuo Chao‐Cheng , Chan Hao , Hung Wei‐Chen , Chen Ruei‐Feng , Yang Hsiu‐Wen , Min Ming‐Yuan 
Published: November 2022

AbstractThe locus coeruleus (LC) consists of noradrenergic (NA) neurons and plays an important role in controlling behaviours. Although much of the knowledge regarding LC functions comes from studying behavioural outcomes upon administration of muscarinic acetylcholine receptor (mAChR) agonists into the nucleus, the exact mechanisms remain unclear. Here, we report that the application of carbachol (CCh), an mAChR agonist, increased the spontaneous action potentials (sAPs) of both LC‐NA neurons and local inhibitory interneurons (LC I‐INs) in acute brain slices by activating M1/M3 mAChRs (m1/3AChRs). Optogenetic activation of LC I‐INs evoked inhibitory postsynaptic currents (IPSCs) in LC‐NA neurons that were mediated by γ‐aminobutyric acid type A (GABAA) and glycine receptors, and CCh application decreased the IPSC amplitude through a presynaptic mechanism by activating M4 mAChRs (m4AChRs). LC‐NA neurons also exhibited spontaneous phasic‐like activity (sPLA); CCh application increased the incidence of this activity. This effect of CCh application was not observed with blockade of GABAA and glycine receptors, suggesting that the sPLA enhancement occurred likely because of the decreased synaptic transmission of LC I‐INs onto LC‐NA neurons by the m4AChR activation and/or increased spiking rate of LC I‐INs by the m1/3AChR activation, which could lead to fatigue of the synaptic transmission. In conclusion, we report that CCh application, while inhibiting their synaptic transmission, increases sAP rates of LC‐NA neurons and LC I‐INs. Collectively, these effects provide insight into the cellular mechanisms underlying the behaviour modulations following the administration of muscarinic receptor agonists into the LC reported by the previous studies.
Efficacy and safety of non‐ergot dopamine‐receptor agonists as an adjunct to levodopa in advanced Parkinson's disease: A network meta‐analysis
Authors: Chen Xiang‐Ting , Zhang Qian , Wen Si‐Yuan , Chen Fei‐Fei , Zhou Chang‐Qing 
Published: November 2022

AbstractBackground and purposeNon‐ergot dopamine agonists (NEDAs) have been used as an adjunct therapy to levodopa in advanced Parkinson's disease (PD) for many years. However, there is no strong evidence that a given NEDA is more potent than another. To compare and rank the efficacy, tolerability, and safety of six commonly used NEDAs as an adjunct to levodopa in advanced PD, which includes long‐acting and standard formulations, a network meta‐analysis was performed.MethodsThe MEDLINE, Embase, Cochrane Central Register of Controlled Trials, China National Knowledge Infrastructure, and Wanfang databases were searched from January 1996 to June 2022 for eligible randomized controlled trials (RCTs). Six NEDAs, including rotigotine transdermal patch, ropinirole immediate‐release (IR)/prolonged‐release (PR), pramipexole IR/extended‐release (ER), and piribedil, were investigated.ResultsA total of 34 RCTs (7868 patients) were included in the current study. The surface under the cumulative ranking curve indicated that ropinirole PR was associated with the best improvement in Unified Parkinson's Disease Rating Scale (UPDRS)‐II, UPDRS‐III, and UPDRS‐II + III (0.811, 0.742, and 0.827). For OFF time reduction, pramipexole IR ranked first (0.979), and ropinirole PR ranked first in OFF time responder rate (0.927). Pramipexole ER ranked first in overall withdrawals, and rotigotine transdermal patch ranked first in the incidence of adverse events (≥1 AEs).ConclusionsThis network meta‐analysis suggests six commonly used NEDAs are effective as an adjunct to levodopa in advanced PD. In comprehensive consideration of better symptomatic management, ropinirole PR may be a better choice than other NEDAs in advanced PD. Six NEDAs showed different profiles of AEs.
Culturally adapting an evidence‐based parenting intervention for the Chilean context: Balancing fidelity, context, and cultural relevance
Authors: Parra‐Cardona Rubén , Banderas Montalva José Miguel , Muñoz Retamal Viviana , Cantizano Rioseco Luz , Perry Mitchell Raúl , Amador Buenabad Nancy , Domenech Rodríguez Melanie 
Published: November 2022

AbstractThe dissemination of evidence‐based parent training (PT) interventions remains extremely limited in Latin American countries. This is concerning when considering the high prevalence of child maltreatment associated with punitive parenting practices across countries in the region. Furthermore, efforts to disseminate PT interventions must be conducted by adhering to the core parenting components that have established effectiveness for such interventions, while ensuring contextual and cultural relevance for focus populations. In this manuscript, we describe the cultural adaptation of an evidence‐based PT intervention in the context of Chile. This initial phase of adaptation was informed by the theoretical tenets of the Ecological Validity Model of cultural adaptation (Bernal et al., J. Abnorm. Child Psychol., 23, 1995, 67). According to findings from a qualitative thematic analysis conducted with five interventionists in training, therapists perceived that the intervention's core components were relevant to Chilean caregivers who participated in the parenting program. Interventionists also provided specific suggestions to enhance the intervention's contextual and cultural relevance. This investigation illustrates the importance of culturally adapting evidence‐based interventions according to comprehensive cultural adaptation frameworks, prior to engaging in large‐scale dissemination of adapted interventions in Latin American contexts.
Experimentation, modelling, and simulation of hydrochory in an Amazonian river
Authors: da Silva Ezequiel Barbosa , Crizanto Jonathan Luz Pires , de Abreu Carlos Henrique Medeiros , dos Santos Eldo Silva , Cunha Helenilza Ferreira Albuquerque , Brito Alaan Ubaiara , de Oliveira Gilvan Portela , Oliveira Leidiane Leão , Mortati Amanda Frederico , André Thiago , Schöngart Jochen , Piedade Maria Teresa Fernandez , da Cunha Alan Cavalcanti 
Published: November 2022

Abstract

Seed transport by hydrochory is a key mechanism of long‐distance dispersal constrained by attributes of the seed and hydrodynamics of the river, influenced by seasonal precipitation and hydrological pulses. However, the extent to which a hydrodynamic model can predict seed dispersal influenced by a tributary is unknown.

The study was conducted along a 10‐km stretch of the Falsino River in Amapá, Brazil. Hydrodynamic parameters from the 2021 rainy season were used to calibrate a three‐dimensional numerical model (SisBaHia) and simulate hydrochory of Macrolobium bifolium, a widely distributed species in the Amazon floodplains. This model was coupled with a Lagrangian dispersal model to estimate the average transport distance of the fruit plume. The simulated results were compared statistically with those of dispersal quantified in the field.

The field experiment coincided with the maximum hydrological pulse, providing with a maximum potential distance of longitudinal dispersal fruit of c. 10 km in 2 hr. The orders of magnitude of the mean plume transport (observed and numerically simulated centre of mass) were compatible with each other over six longitudinal tracking sections (4.0% ≤ estimated × observed error ≤ 16.5%). Different channel stretches had distinct hydraulic characteristics that influenced spatial dispersal dynamics and are likely to be factors influencing the distribution of M. bifolium in these environments.

The present research is a contribution to understanding fluvial hydrodynamics and hydrochory by M. bifolium, whose seed dispersal syndrome is an adaptive characteristic that might explain its abundance and richness in these Amazonian riparian zones. We used M. bifolium as a model species to understand the role of seasonal flood pulse and fluvial hydrodynamics related to hydrochory favouring.