bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chronic inflammatory back pain commencing late in life: a neglected concept
Authors: Rianon Nahid J. , Lee MinJae , des Bordes Jude K. , Rahbar Mohammad H. , Weisman Michael H. , Reveille John D. 
Published: March 2022

AbstractChronic inflammatory back pain (CIBP) occurs in up to one‐third of those with chronic back pain. Criteria for diagnosis of inflammatory back pain include an onset below 50 years. Using the US National Health and Nutrition Examination Survey data for 2009–2010, we showed that 3% of adults aged 50–69 years have features of CIBP with onset on or after 50 years. There is little information in the literature on CIBP of late onset. Patients with late onset CIBP may be falling through the cracks.
Nurses’ experiences of accompanying patients dying during the COVID‐19 pandemic: A qualitative descriptive study
Authors: Castaldo Anna , Lusignani Maura , Papini Marzia , Eleuteri Stefano , Matarese Maria 
Published: March 2022

AbstractAimsThe aim was to explore nurses’ experiences of caring for and accompanying patients dying without the presence of family during the COVID‐19 pandemic.DesignA qualitative descriptive design was used.MethodsA purposive sample of registered nurses, caring for dying patients in Italian health‐care settings during the COVID‐19 pandemic, were selected. To capture a broad range of experiences, a maximum variety of participants about workplace, age, gender and work experience were included. A total of 31 nurses agreed to participate in the study; 28 participants were female; participants were aged 41 on average (range 25–63 years) and worked in hospitals and nursing homes in the Northern and Central Italian regions. Six focus groups were conducted from August to December 2020 through Microsoft Teams, reaching data saturation. The transcripts were analysed through inductive content analysis. The COREQ checklist was followed for study reporting.ResultsFour main categories emerged describing nurses’ experiences: hugely increased deaths in time of COVID‐19; ensuring physical, emotional, interpersonal and spiritual care for dying patients and supporting their families despite difficulties; ensuring care procedures of patients’ bodies after death and psychological consequences of caring for dying people during the pandemic.ConclusionRegistered nurses provided physical, spiritual and emotional care to dying patients during the pandemic, despite limited resources and knowledge, standing in for relatives who were not allowed to visit them; the experiences of caring for dying patients in the absence of the family caused emotional distress in nurses.ImpactHealth‐care systems should develop guidelines aiming to meet the psychological needs of dying people in case of restrictions on patients’ family visits. Health‐care administrators should offer services to support the grieving process of relatives who cannot accompany dying patients and to reduce emotional distress in nurses caring for dying patients.
Nurses' perspective on their involvement in decision‐making about life‐prolonging treatments: A quantitative survey study
Authors: Arends Susanne A. M. , Thodé Maureen , De Veer Anke J. E. , Pasman H. Roeline W. , Francke Anneke L. , Jongerden Irene P. 
Published: March 2022

AbstractAimsIn hospital settings, decisions about potentially life‐prolonging treatments are often made in a dialogue between a patient and their physician, with a focus on active treatment. Nurses can have a valuable contribution in this process, but it seems they are not always involved. Our aim was to explore how hospital nurses perceive their current role and preferred role in shared decision‐making about potentially life‐prolonging treatment in patients in the last phase of life.DesignCross‐sectional quantitative study conducted in the Netherlands in April and May 2019.MethodsAn online survey, using a questionnaire consisting of 12 statements on nurses' opinion about supporting patients in decisions about potentially life‐prolonging treatments, and 13 statements on nurses' actual involvement in these decisions.ResultsIn total 179 hospital nurses from multiple institutions who care for adult patients in the last phase of life responded. Nurses agreed that they should have a role in shared decision‐making about potentially life‐prolonging treatments, indicating greatest agreement with ‘It is my task to speak up for my patient’ and ‘It is important that my role in supporting patients is clear’. However, nurses also said that in practice they were often not involved in shared decision‐making, with least involvement in ‘active participation in communication about treatment decisions’ and ‘supporting a patient with the decision’.ConclusionThere is a discrepancy between nurses' preferred role in decision‐making about potentially life‐prolonging treatment and their actual role. More effort is needed to increase nurses' involvement.ImpactNurses' contribution to decision‐making is increasingly considered to be valuable by the nurses themselves, physicians and patients, though involvement is still not common. Future research should focus on strategies, such as training programs, that empower nurses to take an active role in decision‐making.
Make‐or‐buy decisions for industrial additive manufacturing
Authors: Friedrich Anne , Lange Anne , Elbert Ralf 
Published: March 2022

AbstractMuch of the potential of industrial additive manufacturing (AM) is said to lie in the digital specification of components that can be transmitted seamlessly and unambiguously to partners fostering flexible outsourcing. In industry, we observe nuanced AM supply chain governance structures that result from make‐or‐buy decisions, with a tendency to implement AM in‐house. Thus, there is a discrepancy between what is discussed in the literature and implemented in practice. We apply a multiple‐case study approach to investigate why and how AM impacts the make‐or‐buy decision of manufacturing firms. We identify four decision profiles demonstrating the spectrum of specific governance structures and develop a framework to explain the underlying rationales. We find strong arguments for in‐house AM including firms’ perceived need to protect their digitally encapsulated intellectual property, reevaluation of their core competencies, commitment to internal learning, and senior management's enthusiasm for AM. By using transaction cost economics and the resource‐based view, we contribute to the understanding of how arguments of these general theories are modified by the digital and emerging traits of AM. We reveal contradicting guidance in the theories’ argumentation for the case of AM and provide managers a clear perspective on alternative strategies for their AM implementation process.
Re‐viewing performance: Showing eye‐tracking data as feedback to improve performance monitoring in a complex visual task
Authors: Kok Ellen , Hormann Olle , Rou Jeroen , van Saase Evi , van der Schaaf Marieke , Kester Liesbeth , van Gog Tamara 
Published: March 2022

AbstractBackgroundPerformance monitoring plays a key role in self‐regulated learning, but is difficult, especially for complex visual tasks such as navigational map reading. Gaze displays (i.e. visualizations of participants' eye movements during a task) might serve as feedback to improve students' performance monitoring.ObjectivesWe hypothesized that participants who review their performance based on screen recordings that also display their gaze would have a higher monitoring accuracy and increase in post‐test performance and would remember more executed actions than participants who review based on a screen recording only (i.e. control condition).MethodsSixty‐four higher education students were randomly assigned to a gaze‐display or control condition. After watching an instruction video, they practiced five navigational map‐reading tasks and then reviewed their performance while thinking aloud, either prompted by a screen recording with gaze display or a screen recording only. Before and after reviewing, participants estimated the number of correctly solved tasks and finally made a five‐item post‐test.Results and conclusionsAnalyses with frequentist and Bayesian statistics showed that gaze displays did not improve monitoring accuracy (i.e. estimated minus actual performance), post‐test performance, or the number of reported actions. It is concluded that scanpath gaze displays do not provide useful cues to improve monitoring accuracy in this task.TakeawaysGaze displays are a promising tool for education, but scanpath gaze displays did not help to enhance monitoring accuracy in a navigational map‐reading task.
Fibroblast growth factor 21 reverses high‐fat diet‐induced impairment of vascular function via the anti‐oxidative pathway in ApoE knockout mice
Authors: Huang Wen‐Pin , Chen Chi‐Yu , Lin Tzu‐Wen , Kuo Chin‐Sung , Huang Hsin‐Lei , Huang Po‐Hsun , Lin Shing‐Jong 
Published: March 2022

AbstractCirculating endothelial progenitor cells (EPCs), which function in vascular repair, are the markers of endothelial dysfunction and vascular health. Fibroblast growth factor 21 (FGF21), a liver‐secreted protein, plays a crucial role in glucose homeostasis and lipid metabolism. FGF21 has been reported to attenuate the progression of atherosclerosis, but its impact on EPCs under high oxidative stress conditions remains unclear. In vitro studies showed that the β‐klotho protein was expressed in cultured EPCs and that its expression was upregulated by FGF21 treatment. Hydrogen peroxide (H2O2)‐induced oxidative stress impaired EPC function, including cell viability, migration and tube formation. Pretreatment with FGF21 restored the functions of EPCs after the exposure to H2O2. Administration of N(ω)‐nitro‐L‐arginine methyl ester (L‐NAME), an inhibitor of nitric oxide synthase, inhibited the effects of FGF21 in alleviating oxidative injury by suppressing endothelial nitric oxide synthase (eNOS). In an in vivo study, the administration of FGF21 significantly reduced total cholesterol (TC) and blood glucose levels in apolipoprotein E (ApoE)‐deficient mice that were fed a high‐fat diet (HFD). Endothelial function, as reflected by acetylcholine‐stimulated aortic relaxation, was improved after FGF21 treatment in ApoE‐deficient mice. Analysis of mRNA levels in the aorta indicated that FGF21 increased the mRNA expression of eNOS and upregulated the expression of the antioxidant genes superoxide dismutase (SOD)1 and SOD2 in ApoE‐deficient mice. These data suggest that FGF21 improves EPC functions via the Akt/eNOS/nitric oxide (NO) pathway and reverses endothelial dysfunction under oxidative stress. Therefore, administration of FGF21 may ameliorate a HFD‐induced vascular injury in ApoE‐deficient mice.
The effect of pipe development length on flow characteristics in a larvae killing system: Screening the dilute phase by CFD
Authors: Mohammadzadeh Peyman , Shahgholi Gholamhossein , Rezvanivand Fanaei Adel , Rostampour Vahid 
Published: March 2022

AbstractOptimal design of conveying path can be lead to decrease the reverse flow and blockage in the conveying processes. In the present study, the effects of four different initial pipe lengths of 190, 380, 570, and 760 mm in the larvae killing machine were evaluated, comprehensively. The numerical calculations were conducted by computational fluid dynamics. Also, the Discrete Phase Model (DPM) and Reynolds Stress Model (RSM) were utilized to model the solid–gas interactions and turbulence of the flow, respectively. According to the results, the minimum pressures drop resulted in configuration III with 159 Pa. A negative pressure field was created in the interior radius of the second elbow, which is due to the enhancement of velocity in this area and an enhancement in dynamic pressure. Moreover, the maximum and minimum vorticity magnitudes were obtained in configurations I and III, respectively. Finally, considering all conditions, configuration III was chosen as the best configuration.Practical ApplicationThe larvae killing machine is utilized to eliminate larvae from whet during conveying. The appropriate design of the piping system is a critical subject in this field. One of the powerful methods for designing the conveying system is computational fluid dynamics. The results of the study can reduce the pressure drop and increase the efficiency of the system and provide uniform conveying in this machine.
A personal and relational model of father identity construction
Authors: Kuscul G. Hilal , Adamsons Kari 
Published: March 2022

AbstractAlthough extensive, the identity theory literature does little to explain how specific identities are constructed. Developmental and sociological work primarily have focused on either images of possible future selves in adolescence, or established identities in adulthood and their impacts on behavior. To date, little work has connected the two realms or proposed what processes occupy the “black box” of identity creation between adolescence and adulthood. To begin to address this gap, we use identity theory to propose a model of father identity construction, focusing on the influence of personal and relational characteristics. Specifically, we propose that the formation of men's status and role identities as fathers are shaped by paternal self‐efficacy and existing identity hierarchies, as well as their experiences with their own fathers and fathering role models and the views of their partners–coparents. Implications and additional applications of the model are elaborated.
Impact of the 24/7 nurse practitioner model on emergency department stay at a level 1 trauma center: A retrospective study
Authors: Hardway Jessica , Lucente Frank C , T Crawford Adam , Jarrouj Aous , Samanta Damayanti 
Published: March 2022

AbstractAimsThe aim of the study was to assess the impact of 24/7 trauma nurse practitioner service model on the emergency department patient flow.BackgroundSeamless transition of trauma patients through the emergency department to inpatient hospital care is crucial for coordination of care, clinical safety and positive health outcomes. A level 1 trauma centre located in Southern West Virginia, USA expanded their trauma nurse practitioner service covering the emergency department 24/7.DesignRetrospective cohort study conducted in accordance with the Strengthening the Reporting of Observational studies in Epidemiology guidelines.MethodsPatients admitted to the trauma centre between March 2019 and February 2020 were divided into two groups: trauma patients managed by trauma nurse practitioners versus the hospitalist service. The hospital service group was chosen as the comparator group because any admission prior to night coverage by the trauma nurse practitioners were managed by the hospitalist service.ResultsThe emergency department length of stay was significantly lower in trauma nurse practitioners' patients by an average of 300 min (772.25 ± 831.91 vs. 471.44 ± 336.65, p = <.001). Similarly, time to place emergency department discharge order was shorter by 49 min (277.76 ± 159.69 vs. 228.27 ± 116.04, p = .001) for this group. Moreover, trauma nurse practitioners on an average placed one less consultation (1.06 ± 0.23 vs. 1.46 ± 0.74, p < .001).ConclusionThe patient care provided by trauma nurse practitioners aided in the reduction of strain felt by their emergency department. They were able to help facilitate patient flow thus lessening the pressure of boarding in an overcrowded emergency department. The study institution hopes to sustain the current service model and continue to review outcomes and processes managed by trauma nurse practitioners to ensure consistency and quality.Relevance to Clinical PracticeSimilar trauma centres should evaluate the structure of their trauma service that includes the role of trauma nurse practitioner service and work towards allowing them to manage patient care from the emergency department 24/7.
Choosing Wisely in clinical practice: Embracing critical thinking, striving for safer care
Authors: Furlan Ludovico , Francesco Pietro Di , Costantino Giorgio , Montano Nicola 
Published: March 2022

AbstractIn recent years, the Choosing Wisely and Less is More campaigns have gained growing attention in the medical scientific community. Several projects have been launched to facilitate confrontation among patients and physicians, to achieve better and harmless patient‐centered care. Such initiatives have paved the way to a new “way of thinking.” Embracing such a philosophy goes through a cognitive process that takes into account several issues. Medicine is a highly inaccurate science and physicians should deal with uncertainty. Evidence from the literature should not be accepted as it is but rather be translated into practice by medical practitioners who select treatment options for specific cases based on the best research, patient preferences, and individual patient characteristics. A wise choice requires active effort into minimizing the chance that potential biases may affect our clinical decisions. Potential harms and all consequences (both direct and indirect) of prescribing tests, procedures, or medications should be carefully evaluated, as well as patients’ needs and preferences. Through such a cognitive process, a patient management shift is needed, moving from being centered on establishing a diagnosis towards finding the best management strategy for the right patient at the right time. Finally, while “thinking wisely,” physicians should also “act wisely,” being among the leading actors in facing upcoming healthcare challenges related to environmental issues and social discrepancies.
Additive Manufacturing for Complete Denture Fabrication: A Narrative Review
Authors: Goodacre Brian J. , Goodacre Charles J. 
Published: March 2022

AbstractPurposeTo evaluate and compare the benefits and limitations of additive manufacturing for complete denture fabrication.MethodsA PubMed and Google Scholar search for topics pertaining to additive manufacturing for complete dentures was performed. The resulting articles were then divided into topics to allow a narrative review.DiscussionDetermining how printing compares with conventional and milled dentures is critical for the widespread adoption of this fabrication technique. Physical properties, denture tooth bond strength, denture base adaptation and soft‐liner bond strength are discussed to establish how printing compares.ConclusionsPrinting offers many advantages over milled and conventionally processed dentures; however, many questions need to be answered by research. The advantages include reduced cost of most printers compared to milling machines, less material waste, ability to print multiple dentures simultaneously, and complex designs can be fabricated that otherwise could not be milled. Current research has shown flexural strength, fracture toughness, color stability, and denture base adaptation are reduced for printed dentures when compared with milled dentures. Print orientation has been shown to influence accuracy, strength, surface roughness and C. albicans adherence which is not seen with conventional or milled denture materials. These factors do not represent a criticism of printing but rather indicate the need for more research with this new and promising denture fabrication technique. Since printing offers numerous benefits to complete denture fabrication it is likely to have a more significant role in complete denture fabrication in years to come as knowledge increases and materials/techniques continue to advance.
Additive Manufacturing Technologies for Fabrication of Biomaterials for Surgical Procedures in Dentistry: A Narrative Review
Authors: Özcan Mutlu , Magini Eduarda Blasi , Volpato Guilherme Maziero , Cruz Ariadne , Volpato Claudia Angela Maziero 
Published: March 2022

AbstractPurposeTo screen and critically appraise available literature regarding additive manufacturing technologies for bone graft material fabrication in dentistry.Material and MethodsPubMed and Scopus were searched up to May 2021. Studies reporting the additive manufacturing techniques to manufacture scaffolds for intraoral bone defect reconstruction were considered eligible. A narrative review was synthesized to discuss the techniques for bone graft material fabrication in dentistry and the biomaterials used.ResultsThe databases search resulted in 933 articles. After removing duplicate articles (128 articles), the titles and abstracts of the remaining articles (805 articles) were evaluated. A total of 89 articles were included in this review. Reading these articles, 5 categories of additive manufacturing techniques were identified: material jetting, powder bed fusion, vat photopolymerization, binder jetting, and material extrusion.ConclusionsAdditive manufacturing technologies for bone graft material fabrication in dentistry, especially 3D bioprinting approaches, have been successfully used to fabricate bone graft material with distinct compositions.
Evaluation of hybrid rice parental lines against bacterial blight disease and detection of resistant gene (s) by gene‐specific, linked markers
Authors: Akter Anowara , Nihad Sheikh Arafat Islam , Hasan Md. Jamil , Hassan Lutful , Robin Arif Hasan Khan , Quddus Md. Ruhul , Tabassum Anika , Latif Mohammad Abdul 
Published: March 2022

AbstractBacterial blight (BB) disease, caused by Xanthomonas oryzae pv. oryzae (Xoo), is one of the major bottlenecks of rice (Oryza sativa) production. The present study was undertaken to identify BB‐resistant parental lines of hybrid rice based on pathogenicity tests and molecular screening. Three virulent races of Xoo, i.e. BXo93, BXo822 and BXo887 were used to evaluate the 66 maintainers and 200 elite restorer lines against BB. Based on the pathogenicity test, none of the maintainer lines was found resistant, whereas 16 restorers were resistant against the three races and 15 restorers were resistant to a single race (Bxo93). These 31 restorer lines were selected to detect the presence of major bacterial blight resistance genes, i.e. Xa4, xa5, Xa7, xa13, Xa21 and Xa23 using molecular markers. Thirteen restorer lines carried the Xa4 gene but were not resistant to all three races of BB. Fourteen restorers and one restorer had two (Xa4 + xa5; Xa4 + Xa7; Xa4 + Xa21 and Xa7 + Xa21) and three (Xa4 + xa5 + Xa7) BB resistance genes, respectively. Genotypes having Xa21, Xa7 + Xa21 or Xa4 + Xa21 had reduced lesion lengths that ranged from 1.4 cm (against BXo93)–3.0 cm (against BXo887), 1.6 cm (against BXo93)–2.0 cm (against BXo822 and BXo887) and 2.5 cm (against BXo887)–3 cm (against BXo822), respectively, and were found to be the most effective resistance genes against bacterial blight. The restorer lines having the Xa21, Xa7 + Xa21 or Xa4 + Xa21 could be used as parental lines for the development of bacterial blight‐resistant hybrid varieties.