bluuebunny/crossref_metadata_2025_split huggingface dataset:
AGENESIA DO CORPO CALOSO EM CRIANÇA: RELATO DE CASO
Authors: Costa Ruth Silva Lima da , Dos Santos Abigail Stefane Ferreira , Correia Felipe Eduardo Silva , De Holanda Glenda Eva Gomes , De Lima Alessandre Gomes 
Published: September 2022

Objetivo: Descrever o relato de caso de agenesia do corpo caloso. Detalhamento do caso: Trata-se de um estudo observacional do tipo descritivo, realizado através dos dados clínicos de uma paciente pediátrica acometida pela agenesia do corpo caloso. A criança atualmente encontra-se com 7 anos de idade, porém foi diagnosticada com a doença desde os 8 meses, através da correlação do diagnóstico clínico com exames de imagem. Ela apresentou retardo no desenvolvimento neuropsicomotor e déficit cognitivo, dificuldade para comer e engolir e em comunicar-se e socializar-se, além problemas de aprendizagem, que são manifestações clínicas habituais da doença. Tem realizado tratamento com fenobarbital na tentativa de evitar as convulsões, bem como o acompanhamento multiprofissional com médico, fisioterapeuta e fonoaudiólogo para melhorar a força muscular e a coordenação, na tentativa de melhorar sua qualidade de vida. Considerações finais: A pesquisa ressaltou a importância de se tornar mais evidente a doença em questão, a fim de subsidiar o trabalho dos profissionais de saúde frente a ela, através da elaboração de novos estudos com o objetivo de conhecer melhor a patologia, ajudar na prevenção de fatores de risco e melhorar a qualidade de vida dos portadores.
O uso do Canabidiol no tratamento de doenças neurológicas selecionadas: uma revisão sistemática
Authors: Martins Schlesner Gabriela , Alba Natali Malagri Claudia , Luciano Gevehr Daniel , Hummes Thaines Aleteia 
Published: September 2022

Objetivo: O presente artigo de revisão sistemática tem como objetivo discutir as evidências científicas a respeito do uso do canabidiol (CBD) para tratamento da epilepsia, esclerose múltipla, doença de Alzheimer e doença de Parkinson. Materiais e Métodos: Foram selecionadas 33 publicações entre os anos de 2010 e 2021, em português, inglês e espanhol, das plataformas: Capes, Scielo e PubMed, utizando os seguintes termos de pesquisa: Canabidiol, Epilepsia, Esclerose múltipla, Doença de Alzheimer e Doença de Parkinson. Resultados: Inferiu-se que o canabidiol oferece benefícios terapêuticos e são, geralmente, bem tolerados pelos pacientes portadores de epilepsia e esclerose múltipla. No caso da doença de Parkinson ainda há muitos pontos a serem elucidados a respeito do mecanismo de ação do fármaco sobre a doença. Já para o mal de Alzheimer ainda não há perspectiva de tratamento com o composto, pois os estudos ainda estão na fase pré-clinica. Conclusões: Destaca-se a necessidade de novos estudos que visem elucidar os pontos ainda não esclarecidos a respeito do canabidiol. Desta forma, as aplicações terapêuticas do composto poderão ser ampliadas.
OPTIMIZATION OF PROBIOTIC FEED ADDITIVE "BENTOBAK" FOR INCREASING PRODUCTIVITY OF FARM ANIMALS
Authors: ГАВРИЛОВА Н.Н. , САДАНОВ А.К. , РАТНИКОВА И.А. , ШОРАБАЕВ Е.Ж. , ОРАЗЫМБЕТ С.Э. , ТАУБЕКОВА Г.К. , КАПТАГАЙ Р.Ж. , КОШЕЛЕВА Л.А. , КЕРЕМБЕКОВА У.Ж. , МУСАБЕКОВ Ж.Т. , ДЖАЙЛАУОВА С.Б. 
Published: September 2022

Разработана оптимизированная пробиотическая кормовая добавка «Бентобак» на основе целлюлолитических бактерий Cellulomonas flavigene-22 и пропионовокислых бактерийPropionibacterim. shermanii С-8, превосходящая исходную по антимикробной активности, целлюлолитической активности, содержанию витамина В12, содержанию жизнеспособных бактериальных клеток в жидкой культуре, бактериальной пасте и сухой кормовой добавке. Производственные испытания оптимизированного препарата «Бентобак» при откорме крупного рогатого скота показали, что среднесуточный привес животного составляет от 770 до 1400 г на голову в сутки и зависит от продолжительности приема биопрепарата и породы скота. Анализ мясных продуктов, взятых из крестьянских хозяйств, участвовавших в эксперименте, показал, что все они соответствовали по органолептическим, химическим и микробиологическим показателям мясу крупного рогатого скота по ГОСТ 7269–79. Отсутствие в отобранных образцах мяса сульфата меди и патогенных микроорганизмов также подтверждает их пригодность.
An optimized probiotic feed additive «Bentobak» based on cellulolytic bacteria Cellulomonas flavigene-22 and propionic acid bacteria Propionibacterim has been developed. shermanii S-8 superior in antimicrobial activity, cellulolytic activity, vitamin V12 content, viable bacterial cell content in liquid culture, bacterial paste and dry feed additive. Production tests of the optimized «Bentobak» drug when fattening cattle showed that the average daily animal weight gain is from 770 to 1400 g per head per day and depends on the duration of taking the biologics and livestock breed. Analysis of meat products taken from peasant farms participating in the experiment showed that all of them corresponded to organoleptic, chemical and microbiological indicators of cattle meat according to GOST 7269-79. Another sign of the suitability of meat is the absence of copper sulfate in it in accordance with GOST 23392-78. Meat obtained from peasant farms did not contain microorganisms that cause diseases.
CREATION OF KAZBIOSIL BIOPREPARATION IN LIQUID AND DRY FORM
Authors: ГАВРИЛОВА Н.Н. , САДАНОВ А.К. , РАТНИКОВА И.А. , ШОРАБАЕВ Е.Ж. , ОРАЗЫМБЕТ С.Э. , ТАУБЕКОВА Г.К. , КАПТАГАЙ Р.Ж. , КОШЕЛЕВА Л.А. , КЕРЕМБЕКОВА У.Ж. , МУСАБЕКОВ Ж.Т. , ДЖАЙЛАУОВА С.Б. 
Published: September 2022

В результате проведенных исследований разработаны оптимальные питательные среды для культивирования молочнокислых и пропионовокислых батерий при производстве заквасок «Казбиосил». Установлено, что срок годности жидкой закваски при хранении без протектора при температуре 6-8°С составляет 3 месяца со дня изготовления, а с сахарозой или сахарозой в сочетании с желатином в качестве протекторов – 4 месяца. При производстве сухой закваски «Казбиосил» сублимационное высушивание концентрированной с помощью центрифугирования биомассы бактерий проводят с использованием в качестве протекторов 7% сахарозы, 1,5% желатина и 7% сухого обезжиренного молока. В качестве наполнителя при стандартизации сухого концентрата бактерий до необходимого титра рекомендовано использовать сухое обезжиренное молоко или картофельный крахмал. Установлено, что при хранении в холодильнике срок годности сухих препаратов «Казбиосил», приготовленных по разработанной технологии, составляет 12 месяцев со дня изготовления. Показано, что с помощью жидкой и сухой заквасок «Казбиосил» можно получать качественный корм из различного вида растительного сырья.
As a result of the studies, optimal culture media for the cultivation of lactic acid and propionic acid baterias in the production of Kazbiosil starters were developed. The shelf life of the liquid starter during storage without a tread at a temperature of 6-8 ° C is found to be 3 months from the date of manufacture, and with sucrose or sucrose in combination with gelatin as protectors - 4 months. During production of Kazbiosil dry starter, sublimation drying of bacteria biomass concentrated by centrifugation is carried out using 7% sucrose, 1.5% gelatin and 7% defatted milk powder as protectors. It is recommended to use dry defatted milk or potato starch as a filler when standardizing the dry concentrate of bacteria to the required titer. It was established that when stored in a refrigerator, the shelf life of Kazbiosil dry preparations prepared according to the developed technology is 12 months from the date of manufacture. It has been shown that with the help of liquid and dry starter "Kazbiosil" it is possible to obtain high-quality feed from various types of vegetable raw materials.
Pengaruh Model Pembelajaran Kooperatif Tipe Think Pair Share dengan Pendekatan Saintifik terhadap Hasil Belajar Peserta Didik
Authors: Pardede Hebron , Nagur Melani Dewi , Silaban Bajongga , Nababan Tulus , Turnip Agnes 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui pengaruh Model Pembelajaran Kooperatif Tipe Think Pair Share dengan Pendekatan Saintifik Terhadap Hasil Belajar Peserta Didik SMP Negeri 7 Medan. Jenis penelitian ini adalah quasi experiment dengan desain penelitian nonequivalent control group design. Populasi penelitian ini yaitu seluruh peserta didik kelas VII SMP Negeri 7 Medan. Teknik sampling yang digunakan dalam penelitian ini adalah purposive sampling. Sampel penelitian ini terdiri dari dua kelompok yaitu kelas eksperimen dan kelas kontrol. Kelas VII-4 sebagai kelas eksperimen dan VII-1 sebagai kelas kotrol. Instrumen penelitian yang digunakan adalah lembar aktivitas peserta didik dan soal berbentuk pilihan berganda untuk mengetahui hasil belajar peserta didik. Berdasarkan hasil belajar peserta didik, nilai rata-rata posttest kelas eksperimen sebesar 81,25 dengan standar deviasi 10,25 dan rata-rata posttest kelas kontrol sebesar 70,94 dengan standar deviasi 9,35. Hasil yang diperoleh melalui uji-t satu pihak untuk data posttest pada kelas eksperimen dan kelas kontrol untuk ? = 0,05 diperoleh thitung = 3,05 dan ttabel = 1,70, dalam hal ini Ho ditolak dan Ha diterima. Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat pengaruh yang signifikan model pembelajaran kooperatif tipe think pair share dengan pendekatan saintifik terhadap hasil belajar peserta didik pada materi kalor dan perpindahannya kelas VII SMP Negeri 7 Medan.
Penerapan Model Atik dalam Pengembangan Motorik Kasar pada Anak ADHD di TK Global Persada Mandiri
Authors: Jacob Anna Maria , Watini Sri 
Published: September 2022

Kegiatan bermain dan olah raga adalah kegiatan yang sangat menyenangkan yang dilakukan di satuan PAUD, karena merupakan bagian dari pengembangan motoric bagi anak yang berguna untuk mengasah kematangan dalam fisik kinestetik, pengembangan bahasa, kognitif, kontrol diri dan sosial skill. Pendidikan anak usia dini adalah suatu instansi badan penyelenggraan Pendidikan yang menitik beratkan kepada 6 pondasi dasar tumbh kembang anak yang mencangkup pengembangan agama dan moral, fisik motorik, kognitif, bahasa, sosial, emosional dan seni seperti yang tercantum di dalam (Mendikbudristek, 2021). Guru dituntut untuk mengembangkan model pembelajaran yang kreatif dan holistic, khususnya dalam mengajar anak-anak yang mempunyai karakter serta kebutuhan yang berbeda. Salah satu model pembelajaran anak usia dini yang sangat dikenal dengan model ATIK ( Amati, Tiru dan kerjakan) (Watini, 2020). Anak usia dini dalam pertumbuhannya belajar dimulai dari pengamatan yang di dapat dari stimulasi ligkungan sekitar. Anak akan memakai penginderaan dalam tubuh untuk mengamati kemudian meniru sebagai hasil pebelajaran yang di dapat. Penggunaan model ATIK dalam kegiatan pengembangan kegiatan bermain dan olah gerak tubuh di TK Global Persada Mandiri bagi siswa ADHD diharapkan dapat meningkatkan kemampuan anak dalam mengembangkan motorik kasar dengan cara mengamati, menirukan dan mempraktikan proses kegiatan. Penelitian ini bertujuan untuk mengetahui tentang penerapan model ATIK dalam kegiatan pengembangan motoric kasar dalam bermain dan mengikuti senam tubuh anak ADHD usia 4-6 tahun di TK Global Persada Mandiri. Penelitian ini dibuat dengan menggunakan kualitatif deskriptif.
Penggunaan Channel TV Sekolah sebagai Media Pembelajaran pada Anak Kelompok B di TK Pertiwi IV Serui
Authors: Burumi Yeni Agustina , Watini Sri 
Published: September 2022

Dalam penulisan ini, penulis akan membahas tentang tujuan manfaat penggunaan Channel Tv sekolah sebagai media belajar dalam meningkatkan proses belajar mengajar di dalam dan di luar Kelas. Selain itu juga tujuan lain dari Channel TV Sekolah yaitu sebagai pesan pendidik dan juga sebagai sumber belajar yang menarik perhatian dan minat Anak Usia Dini khususnya pada anak-anak di Lembaga Tk Pertiwi IV Serui. Dalam penelitian dilapangan penulis mengumpulkan semua data kegiatan siswa sesuai dengan apa yang terjadi, yang sudah dilakukan dalam proses belajar mengajar melalui teknik Penelitian: 1.Study Pustaka 2.Observasi 3. Wawancara 4.Dokumentasi. Dari hasil kajian ini maka penulis dapat melihat manfaat penggunaan Tv Sekolah menjadi dampak positif bagi karateristik Anak Usia Dini. Oleh sebab itu dengan adanya Channel TV Sekolah maka penulis banyak mengkreasikan proses belajar mengajar yang kreatif dan bervariasi dengan menggunakan Tv Sekolah sebagai media pembelajaran dan juga dapat menciptakkan generasi anak-anak yang berakhlak mulia, bersosialisai, berkarakter, cinta tanah air menuju Bangsa Indonesia yang maju, kreatif, berjiwa Nasionalisme dalam pendidikan Nasional. Dari hasil obeservasi, wawancara dan dokumentasi maka hasil penelitian membuktikan bahwa manfaat, karakteristik dan kelebihan dari penggunaan Channel Tv Sekolah adalah sebagai media belajar yang efektif dalam proses pembelajaran pada Anak Usia Dini di TK Pertiwi IV.
A Novel Approach by Needles in the Payzone of Heterogeneous Tight Carbonate: A Case Study for Offshore Marginal Field
Authors: Li Rong , Gong Hao , Al-Shamsi Mohamed K. , Feng Peizhen , Lotfy Elbaramawi Mohamed , Al-Neaimi Ahmed , Al-Menhali Helal , Chehabi Wissam , Abdelhamed Wael , Loobari Sultan , Ali Ahmed Ziad , Obeid Ahmad Fayyad 
Published: September 2022

The new Fish-bones Completion & Stimulation approach by needles in the pay stack aims at addressing heterogeneous tight carbonate by increasing flow area in the lower permeable streaks, which is efficient as hundreds of tunnels drain connecting the borewell to the body of the reservoir to increase well productivity and oil recovery. The initial plan includes selecting the best ones from Stair step horizontal well, Dual Lateral well, five lateral fish-bone drilling, and horizontal drilling along with hydraulic fracture. Considering the lessons of failure to clean internal tubes, the modified 4-1/2” Liner is installed in the lower two sub-layer by jetting subs combing with production subs for matrix acidizing in the upper one sub-layer as per modified Fish-bones Completion Design. In addition, special acid-releasing float shoes and new fishing baskets are applied to avoid those previous problems with this well technique. The candidate well shows good oil test and production, which improved by three times at 2000bbl/d with respect to the initial plan in the B field. This paper describes the technology background and characteristics, design factors, modified design, execution, well test, and lessons learned during implementation.
INVESTIGATING THE DIFFICULTIES FACED BY ENGLISH DEPARTMENT STUDENTS IN STRUCTURE AND WRITTEN EXPRESSION SECTION OF TOEFL AT BUNG HATTA UNIVERSITY
Authors: Etika Indah 
Published: September 2022

Abstract
TOEFL has been regulated as one of the graduation requirements at Bung Hatta University with a minimum score of 400 for all majors, including the English Department. However, there are students still failed in achieving the targeted score. The preliminary research showed that English Department students at Bung Hatta University had difficulties in TOEFL, especially the Structure and Written Expression section. Thus, this research aimed to investigate the difficulties faced by students viewed from material and personal factors. Descriptive research was applied as the research method where the sixth-semester students of English Department were chosen as the subject of the research. There were three instruments used in collecting the data of this research which were the researcher as the instrument; the test of Structure and Written Expression section of TOEFL aimed at identifying the students' ability in the test and collecting the data about the materials faced difficult; interview guide to investigate the factors causing them difficult in the test. Then, the result showed that the ability of English Department students in Structure and Written Expression section of TOEFL was 41% in level C, "Moderate." It proved that the Structure and Written Expression section of TOEFL was the most difficult section to answer two other sections (Listening and Reading Comprehension) faced by English Department students at Bung Hatta University. Among the eight indicators of materials tested in the Structure section of TOEFL, Inversion became the most difficult one to answer. The percentage of difficulty for this material was 85,19%. Thus, in finding the factors causing them difficult, seven indicators were interviewed to the subject of the research. Then, Material Comprehension was the most dominant factor causing the students difficult in the test.
La hotelería turística de lujo en España en el primer tercio del siglo xx
Authors: Larrinaga Rodríguez Carlos 
Published: September 2022

La industria hotelera española del primer tercio del siglo xx se caracteriza por una gran diversidad, de manera que en este artículo nos vamos a centrar únicamente en aquellos hoteles dedicados a satisfacer las necesidades de los turistas más exigentes y adinerados. Es decir, establecimientos de lujo y urbanos. Se pretende, por consiguiente, ver la evolución que se produjo en este tipo de hoteles a lo largo de estas tres décadas, analizando las sensibles mejoras que se produjeron en la oferta de este tipo de alojamientos en distintas localidades españolas, tratando de equiparar sus servicios a los existentes en los grandes hoteles de lujo de otros países europeos.
Analysis of The Use of Digital Learning Media Before and After Pandemic
Authors: Siregar Sri Utami Kholilla Mora , Kasmawati  
Published: September 2022

The purpose of this study was to see the extent of student interest in participating in learning before the pandemic through the application of monotonous conventional methods with learning using digital media after the pandemic in class 2018 students of the UGN Padangsidimpuan teaching faculty.
The type of research used in this study is a qualitative research type, for processing data obtained based on observations and publishing a questionnaire that will be answered by all 2018 physics students. In this case, the researcher observes student activities during learning and evaluates at the end of each lesson.
The use of digital learning media for physics students is obtained from research on student answers through questionnaires that can be uploaded via the given page. It is known that 70% of students prefer learning using digital media after the pandemic compared to before the pandemic.
The results of this study were obtained by observing an increase in student interest in learning by using digital learning media in the subject of study and learning of physics students for the 2018 class of the teaching faculty of UGN Padangsidimpuan.
The Influence of Profitability and Liquidity on Firm Value (Case Study on a Non-financial Company Indexed ESG Quality 45 IDX-Kehati on the Indonesia Stock Exchange 2017-2020)
Authors: Akbar Zaki Faturahman , Nusa Inta Budi Setya , Iriyadi . 
Published: September 2022

Aims: This study aims to determine the influence of Profitability and Liquidity on Firm Value, as previous research results were inconclusive, inconsistent, and sometimes contradictory.
Study Design: This research is quantitative correlational research using multiple linear regression.
Methodology: This study uses 35 non-financial companies indexed ESG Quality 45 IDX-Kehati listed on the Indonesia Stock Exchange for 2017-2020. The cross-sectional data are analyzed by SPSS version 25.
Results: This study provides empirical evidence that profitability (ROA) positively and significantly impacts firm value (PBV). As the coefficient value of ROA is +0.115, it means that every a hundred percent increase in Profitability (ROA) will increase the stock price or Firm Value (PBV) by 11.5%. Unexpectedly, the Liquidity (CR) does not affect firm value.
Conclusions: Return on assets as a proxy for profitability ratios has a positive and significant effect on increasing stock market prices to the book value ratio as a proxy for firm value. In contrast, the liquidity ratio does not affect the increase in stock prices. These findings indicate that investors and capital market analysts are more concerned with profitability than liquidity. Therefore, managers and directors must generate maximum net profit by increasing the productivity of all company assets. The limitation of this study is that the sample is small and only uses two predictor variables, so the coefficient of determination (R2) is 28%. For further research, adding other predictor variables and control variables is recommended.
Nb/Al co‐doped Li7La3Zr2O12 Composite Solid Electrolyte for High‐Performance All‐Solid‐State Batteries
Authors: Nguyen Hoang Long , Luu Van Tung , Nguyen Manh Cuong , Kim Sung Hoon , Nguyen Quoc Hung , Nungu Nungu Israel , Jun Yun‐Seok , Ahn Wook 
Published: September 2022

AbstractAll‐solid‐state Li batteries (ASSLBs) are considered suitable candidates to replace conventional batteries utilizing liquid electrolytes. However, the applications of this type of batteries are limited owing to their narrow operating temperature range, low ionic conductivity, poor long‐term stability, and complex production process. Herein, a simple approach that combines all potential battery candidates that have been investigated over the last few years, including polyethylene oxide (PEO), Li7La3Zr2O12 (LLZO), succinonitrile (SN), and Li salt (LiTFSI), is employed to solve the limitations of ASSLBs. LLZO codoped with Al3+ and Nb5+ (NAL) is synthesized at a low temperature using a modified sol‐gel Pechini method. NAL, along with SN, plays a critical role in improving the performance of the resultant solid polymer electrolyte, which can be operated at room temperature. The integrated electrolyte PEO/LiTFSI‐SN‐NAL (PLS‐NAL) delivers a high ionic conductivity of 3.09 × 10−4 S cm−1 and an excellent Li‐ion transference number of 0.75 at room temperature. ASSLBs combining LiFePO4 and PLS‐NAL exhibit excellent cycling stability at both room temperature and 45 °C with a high capacity retention of ≈90% after 200 cycles and cycle life of up to 400 cycles.
Recent Advances of Bismuth Halide Based Nanomaterials for Photocatalytic Antibacterial and Photodynamic Therapy
Authors: Sun Jingyu , Chen Xue , Mo Shudi , Zhang Ze , Guo Donggang , Li Yaohua , Liu Lu 
Published: September 2022

AbstractStudies of layered structure nanomaterials is greatly explored to provide enormous potential for the development of photocatalytic bioapplication. As one of the layered nanomaterials, bismuth halide nanomaterials have attracted much attention due to their outstanding properties, such as excellent optoelectronic performance, higher biosafety, high abundance, etc. Here, a brief review of recent research progress of bismuth halide based nanomaterials (BiONs) in bioapplication is provided, mainly including photocatalytic antibacterial and photodynamic therapy. Surface engineering strategies, including doping, heterojunction, morphology control, vacancy engineering, facet engineering, and others, are employed to develop a high photoactivity and better biological compatibility of BiONs. In this review, the major challenges of BiONs during the photoreaction process are discussed and promising strategies are proposed for superior photocatalytic performance in biological area. It is hoped that this review may offer new insights into the development of highly active nanomaterials in bioapplication.