bluuebunny/crossref_metadata_2025_split huggingface dataset:
FAKTOR-FAKTOR YANG BERHUBUNGAN PEMBERIAN SUSU FORMULA PADA BAYI USIA 0-6 BULAN DI UPT PUSKESMAS KAJUARA TAHUN 2021
Authors: Arfan Nur  
Published: September 2022

Abstract. Formula milk is milk that is specifically formulated as a substitute for breast milk for infants up to 6 months of age. The purpose of this research is to determine the factors related to giving formula milk to infants 0-6 months at UPT Puskesmas Kajuara in 2021. The research used was descriptive analysis with a cross approach. sectional means that the measurement of variables is only done once at a time, and the results of the study were obtained using the results of the chi square test statistic, obtained p-value = 0.001 P <0.05, there is a relationship between education and formula feeding at UPT Puskesmas Kajuara with test results chi square test statistic obtained p-value = 0.004 P <0.05. It means that there is a relationship between the economy and the provision of formula milk at the UPT Puskesmas Kajuara, with the results of the chi square test statistic test obtained p-value = 0.002 P <0.05

Abstrak. Susu formula adalah susu yang secara khusus diformulasikan sebagai pengganti ASI untuk bayi sampai berusia 6 bulan bertujuan Untuk mengetahui faktor-faktor yang berhubungan pemberian susu formula pada bayi 0-6 bulan di UPT Puskesmas Kajuara Tahun 2021, Penelitian yang digunakan adalah analisis deskriptif dengan pendekatan cross sectional artinya pengukuran variabel hanya dilakukan satu kali pada satu saat, dan hasil penelitian didapatkan menggunakan hasil uji statistik chi square test didapatkan p-value = 0,001 P < 0,05, ada hubungan antara pendidikan dengan pemberian susu formula di UPT Puskesmas Kajuara dengan hasil uji statistik chi square test didapatkan p-value = 0,004 P < 0,05. Berarti ada hubungan antara ekonomi dengan pemberian susu formula di UPT Puskesmas Kajuara, dengan hasil uji statistik chi square test didapatkan p-value = 0,002 P < 0,05.
FAKTOR-FAKTOR YANG MEMPENGARUHI KEGAGALAN PEMBERIAN ASI EKSKLUSIF PADA BAYI 0-6 BULAN DI UPT PUSKESMAS KAJUARA
Authors: Sulfianti  
Published: September 2022

Abstract. To determine the factors that influence the failure of exclusive breastfeeding for infants aged 0-6 months at UPT Puskesmas Kajuara in 2021. This study uses a quantitative descriptive method, which aims to present the factors that influence the failure of exclusive breastfeeding in infants 0-6 months by describing a number of variables. The research used is descriptive analysis with a cross sectional approach, meaning that the measurement of variables is only done once at a time. The population in this study were all mothers who gave exclusive breastfeeding in the work scope of the UPT Puskesmas Kajuara Kec. Champion So that the number of samples was determined as many as 25 people. Results: The results showed that there was no relationship between knowledge and exclusive breastfeeding at the UPT Puskesmas Kajuara, with the chi square test results obtained p-value = 0.123 p <0.05. There is a relationship between family support and exclusive breastfeeding at the UPT Puskesmas Kajuara, with the results of the chi square test, p-value = 0.001 p> 0.0.
Abstrak. Untuk Mengetahui faktor-faktor yang mempengaruhi kegagalan pemberian ASI eksklusif pada bayi usia 0-6 bulan di UPT Puskesmas Kajuara tahun 2021. Penelitian ini menggunakan metode deskriptif kuantitatif adalah penelitian yang tujuannya untuk menyajikan faktor-faktor yang mempengaruh kegagalan pemberian Asi Eksklusif pada bayi 0-6 bulan dengan cara mendiskripsikan sejumlah variabel. Penelitian yang digunakan adalah analisis deskriptif dengan pendekatan cross sectional artinya pengukuran variabel hanya dilakukan satu kali pada satu saat yang sama. Populasi dalam penelitian ini adalah semua ibu yang memberikan Asi Eksklusif di lingkup kerja UPT Puskesmas Kajuara Kec. Kajuara Sehingga ditentukan jumlah sampel yaitu sebanyak 25 orang. Hasil penelitian menunjukkan bahwa tidak ada hubungan antara pengetahuan dengan pemberian Asi Ekskl*-sif di UPT Puskesmas Kajuara, Dengan hasi uji chi square test didapatkan p-value=0,123 p<0,05. Ada hubungan Dukungan Keluarrga dengan pemberian Asi Eksklusif di UPT Puskesmas Kajuara, dengan hasil uji chi square test didapatkan p-value=0,001 p>0,0.
PENGARUH PENDIDIKAN IBU DENGAN STATUS GIZI SISWA DI SMK BINA SEHAT NUSANTARA KABUPATEN BONE TAHUN 2022
Authors: Rahmat Irwandi 
Published: September 2022

Abstract. Balanced nutrition is a daily diet that contains nutrients in the type and amount according to the body's needs, namely gender, age and health status. Assessment of a person's nutrition is usually known as nutritional status. The success of a country to develop human resources is highly dependent on the nutritional status of its people. One of the factors that affect a person's nutritional status is people's knowledge of nutrition. One's knowledge can be seen from the level of education. This study aims to see whether there is an effect of the level of mother's education on the nutritional status of students who attend SMK Kesehatan Bina Sehat Nusantara Kabuapaten Bone. This research was conducted with analytical research method with a cross sectional approach. The research subjects were 33 students. Subjects who meet the criteria and are willing to take part in this study will fill out a questionnaire and their nutritional status will be measured through BMI (Body Mass Index). Furthermore, the data will be analyzed using Chi square analysis in the SPSS program. From the chi square analysis, it was found that there was no relationship between maternal education and the nutritional status of students at SMK Bina Sehat Nusantara, Kabupaten Bone. Abstrak. Gizi seimbang adalah susunan makanan sehari-hari yang mengandung zat gizi dalam jenis dan jumlah yang sesuai dengan kebutuhan tubuh yaitu jenis kelamin, umur dan status kesehatan. Penilaian terhadap gizi seseorang biasanya dikenal dengan status gizi. Keberhasilan suatu negara untuk mengembangkan sumber daya manusia sangat bergantung pada status gizi masyarakatnya. Salah satu faktor yang mempengaruhi status gizi seseorang adalah pengetahuan orang tentang gizi. Pengetahuan seseorang salahsatunta dapat dilihat dari tingkat pendidikanya. Penelitian ini bertujuan untuk melihat apakah ada pengaruh tingkat penidikan ibu dengan ststus gizi siswa yang bersekolah di SMK Kesehatan Bina Sehat Nusantara Bone. Penelitian ini dilakukan dengan metode penelitian analitik dengan pendekatan cross sectional. Subjek penelitian adalah pelajar sebanyak 33 orang. Subjek yang memenuhi kriteria dan bersedia mengikuti penelitian ini akan mengisi kuesioner dan akan di ukur status gizinya melalui IMT ( Indeks Massa Tubuh ). Selanjutnya data akan dianalisa menggunakan analisa Chi squere dalam program SPSS. Dari analisa chi squere, didapati tidak ada hubungan antara pendidikan ibu dengan status gizi siswa di SMK Bina Sehat Nusantara Kabupaten Bone.
MOLACULAR DOCKING SENYAWA XANTHORRHIZOL DARI CURCUMA XANTHORRIZA SEBAGAI ANTI INFLAMASI DAN TES ADME PREDICTIONS
Authors: Afriani Arif Nurul , Rezki  , Rahmat Irwandi 
Published: September 2022

Abstract. Enzymes that influence the inflammatory process are cyclooxygenase enzymes that function in forming a prostaglandin to form inflammation. The xanthorrhizol compound has anti-inflammatory effect, so the xanthorrhizol docking research was carried out on the cycloocxigenase enzyme to determine the interaction of xanthorrhizol compounds derived from ginger rhizome (Curcuma xanthorriza). The analysis of these compounds used bioinformatics with several software namely PyMOL v.7.4.5, PyRx 0.8, and Avogadro. This software helps to visualize the compound and see the potential inhibitor of the compound against the cyclooxygenase enzyme. The docking of the xanthorrhizol ligand obtained the -7.4 binding affinity which showed it could interact with the active site of the cyclooxygenase enzyme target protein..
Abstrak. Enzim yang berpengaruh dalam proses inflamasi yaitu enzim cyclooxygenase yang berfungsi dalam membentuk sebua prostaglandin untuk membenntuk inflamasi. Senyawa xanthorrhizol mempunyai efek antiinflamasi, sehingga dilakukan penelitian docking xanthorrhizol terhadap enzim cycloocxigenase untuk mengetahui interaksi senyawa xanthorrhizol yang berasal dari tanaman temulawak (Curcuma xanthorriza) analisis senyawa tersebut menggunakan bioinformatika dengan beberapa soft ware yaitu PyMOL v.7.4.5, PyRx 0.8, dan Avogadro. Softwere ini membantu untuk memvisualisasi senyawa dan melihat potensi inhibitor senyawa terhadap enzim cyclooxigenase. Hasil docking dari ligan xanthorrhizol memproleh binding affinity -7,4 yang menunjukkan dapat berinteraksi dengan sisi aktif protein target enzim ciclooxigenase
Síndrome de ovarios poliquísticos Polycystic ovary syndrome
Authors: Mestanza Sáenz Milthon 
Published: September 2022

El Síndrome de ovarios poliquísticos (SOP) es la endocrinopatía más común de la mujer en edad reproductiva, afecta aproximadamente al 15% de las mujeres en esta etapa de su vida. Es una enfermedad de origen desconocido, multifactorial, con un componente genético importante, con una heredabilidad de 70%.El diagnóstico se realiza utilizando los criterios de Rotterdam, siendo una enfermedad de exclusión. Tiene manifestaciones clínicas a corto plazo como hirsutismo, acné, alopecia y seborrea; y se asocia a resistencia a la insulina, síndrome metabólico, diabetes mellitus, apnea del sueño, cáncer de endometrio y enfermedad cardiovascular.El tratamiento inicial consiste en cambios en el estilo de vida, dieta saludable y ejercicio físico. Si la mujer no tiene deseos de gestar se indicará anticonceptivos orales combinados y si desea gestar, inductores de la ovulación. Si presenta resistencia a la insulina se agregará el uso de metformina.
Endometriosis
Authors: Osorio Torres Carmen Rosa 
Published: September 2022

La endometriosis es una enfermedad de nuevos conceptos; en su definición, diferenciando sus tres fenotipos de presentación: Endometriosis Superficial, Endometrioma ovárico y Endometriosis Profunda; en su diagnóstico, poniendo en valor la sintomatología y sinología clínica en el paciente aunados con el Ultrasonido vaginal y Resonancia magnética de Pelvis los cuales permiten llegar a el sin que sea imprescindible una laparoscopia diagnostica, antes considerada el standard de oro; en su clasificación, agregándose la Clasificación EFI ( Endometriosis Fertility Index) a la Clasificación de ASRM; así como en su Manejo, el cual se propone sea acorde con la edad del paciente y sus prioridades reproductivas, que incluyen el manejo del componente inflamatorio y hormonal mediante AINES y Anticonceptivos orales, el manejo quirúrgico oportuno y completo mediante una cirugía laparoscópica, así como los tratamientos de Reproducción asistida. En pacientes con infertilidad, los tratamientos de reproducción asistida pueden ser prioritarios y previos a la cirugía laparoscópica.
Estudio de la pareja infértil
Authors: Ayllon Rengifo Gabriela 
Published: September 2022

La infertilidad es una enfermedad que afecta aproximadamente al 15% de las parejas en edad fértil. El retraso en el inicio de la maternidad se ha convertido en una de las principales causas de infertilidad. Se considera que el 30% de los casos de deben al factor masculino, 30% al factor femenino, 20% a ambos y 20% son de causa desconocida. La mayoría de las causas de infertilidad se pueden resolver con las técnicas de reproducción asistida de baja o alta complejidad, por lo que hacer un diagnóstico oportuno seguido del tratamiento correspondiente, suele restaurar la fertilidad perdida.
¿Cómo abordar el dolor ocular en consultorio?
Authors: Vargas Chang Patricia , Cárdenas Merino Alfonso 
Published: September 2022

Introducción: consulta oftalmológica ambulatoria, es por ello la importancia en tener en consideración las diferentes patologías que pueden estar asociadas a esta dolencia Objetivos: Realizar una revisión acerca de los tipos de dolor ocular que podemos identificar y patologías más frecuentes asociadas a cada uno de ellos Desarrollo: El V par craneal, es el encargado de brindar inervación sensitiva a las estructuras del rostro y entre ello al globo ocular. Por lo tanto, la respuesta ante una noxa en los propios tejidos oculares como estructuras aledañas pueden causar dolor. Es importante reconocer las características del dolor, la limitación que produce en el paciente y los signos oculares que podemos encontrar a la evaluación para poder llegar al un correcto diagnostico y brindar al paciente un tratamiento adecuado Conclusiones: Es muy interesante estudiar las patologías que pueden provocar dolor ocular, y que en algunas oportunidades representa un reto en el tratamiento del mismo. Por ello es necesario abordar al paciente de forma integral, realizando una exploración detallada y contando también con la evaluación conjunta con otras especialidades que están relacionadas en el campo del dolor ocular.
Tumor Phyllodes de la mama
Authors: Calderón V. Gabriela , Pajuelo M. Alberto , Guerra M. Henry , De la Cruz S. Miguel , Hammond C. Rowena 
Published: September 2022

Introducción: El tumor phyllodes (TP) es un tumor raro de la mama, representa menos del 1% de todas las neoplasias de la mama (1) y el 2 a 3 % de los tumores fibroepiteliales (7). Esta neoplasia se clasifica en: TP Benigno, TP Borderline y TP Maligno (Norris y Taylor-OMS) (9). Objetivo: Realizar una revisión acerca del diagnóstico y tratamiento del tumor phyllodes. Desarrollo: Los TP son neoplasias fibroepiteliales qué de acuerdo a la celularidad estromal, atipia nuclear, tasa mitótica, elementos heterólogos son clasificados como: benignos, borderline y malignos (1). La máxima incidencia se da entre los 35-55 años. El diagnóstico por imágenes se basa en el uso de mamografía, ecografía, resonancia magnética y biopsia core radioguiada. El óptimo manejo quirúrgico constituye la herramienta fundamental en TP. Existe controversia acerca del uso de tratamiento adyuvante con radioterapia y quimioterapia. Conclusiones: TP es una neoplasia benigna de la mama, la cirugía es el tratamiento de elección. El borde libre mayor de 1 cm recomendado por la NCCN es predictivo para un menor porcentaje de recurrencia local. Los tratamientos complementarios con radioterapia y quimioterapia son controversiales.
Desorden linfoproliferativo germinotrópico asociado al HHV8/KSVH y EBV
Authors: Schwarz Luis J , Villena Marco , Poma Nathaly , Barrionuevo Carlos 
Published: September 2022

Describimos el caso de un paciente portador de Desorden Linfoproliferativo Germinotrópico (DLG) Asociado a Virus Epstein Baar (EBV) y herpesvirus 8 (HHV8/KSVH), el primer reporte de esta entidad se realizo en la revista Blood del año 2002 (1) y a la fecha se han descrito alrededor de 20 casos (2,3); esta clasificada dentro de los desordenes linfoproliferativos asociados al herpesvirus 8 (HHV8/KSVH) (4)(5). Clínicamente se caracteriza por presentarse en pacientes inmunocompetentes, como una adenopatía localizada, de curso indolente, con respuesta favorable a la quimioterapia, radioterapia o escisión quirúrgica (6). Histológicamente se observan plasmablastos que marcan positivo a EBV y HHV8/KSVH formando agregados confluentes que tienden a invadir los centros germinales (germinotropismo) (6); al hacer la microdisección de los plasmablastos y estudio cadena de reacción de polimesasa (PCR), muestran un patrón policlonal u oligoclonal, por esto es catalogado como un “desorden” y no como una neoplasia propiamente dicha (6). La linfomagenesis esta dada por la co-infección de una célula B de origen centrogerminal; inicialmente tenemos a las células B como reservorio latente del HHV8/KSVH y posteriormente recibe el “second genetic hit” por el Virus Epstein Barr (EBV) (7), desarrollando en un paciente inmunocompetente el DLG.
Outcome of Pterygium Excision with Conjunctival Autograft in a Tertiary Hospital in Southern Nigeria
Authors: Okonkwo Sunday Nnamdi , Adebayo Dominica Ibhaduwede , Ogbonna Ikenna Kizito 
Published: September 2022

Aim: To report the outcome of pterygium surgery with conjunctival autograft at a tertiary hospital in Southern Nigeria.
Methods: This is a retrospective non comparative study of post operative outcomes in which the medical records of all patients who had pterygium excision with conjunctival autograft from July 2016 to June 2021 at Nigerian Navy Reference Hospital Calabar, Nigeria were reviewed. All the patients were followed up for a minimum of 6 months. Data collected were sex, age, grade of pterygium, indication for pterygium surgery, post operative complications and recurrent pterygium growth.
Results: Forty – three eyes of 38 patients were operated on. There were 23 males and 15 females (M:F = 1.5:1). Age range was 28 to 61 years (mean 40.9 ± 8.4). Age range with the highest surgery was 31 to 40 years. Grade two pterygium accounted for most of the cases (88.4%) followed by grade three (9.3%) and grade one (2.3%). The most common indication for pterygium surgery was cosmetic (55.8%) followed by recurrent inflammation (34.9%) and the least indication was blurring of vision (9.3%).
Of the 43 eyes operated, one had recurrence giving a recurrence rate of 2.3%. One patient each developed granuloma and conjunctival cyst while three patients had subgraft hemorrhage.
Conclusion: Primary pterygium excision with conjunctival autograft has a low recurrence rate consistent with previously published reports.
Predicting Chronic Opioid Use Among Patients With Osteoarthritis Using Electronic Health Record Data
Authors: Mohl Jeff T. , Stempniewicz Nikita , Cuddeback John K. , Kent David M. , MacLean Elizabeth A. , Nicholls Lance , Kerrigan Christopher , Ciemins Elizabeth L. 
Published: September 2022

ObjectiveTo estimate the risk of a patient with osteoarthritis (OA) developing chronic opioid use (COU) within 1 year of a new opioid prescription by using electronic health record (EHR) data and predictive models.MethodsWe used EHR data from 13 health care organizations to identify patients with OA with an opioid prescription between March 1, 2017 and February 28, 2019 and no record of opioid use in the prior 6 months. We evaluated 4 machine learning models to estimate patients’ risk of COU (≥3 prescriptions ≥84 days, maximum gap ≤60 days). We also estimated the transportability of models to organizations outside the training set.ResultsThe cohort consisted of 33,894 patients with OA, of whom 2,925 (8.6%) developed COU within 1 year. All models demonstrated good discrimination, with the best‐performing model (random forest) achieving an area under the receiver operating characteristic curve (AUC) of 0.728 (95% CI 0.711–0.745), but the simplest regression model performed nearly as well (AUC 0.717 [95% CI 0.699–0.734]). Predicted risk deciles spanned a range of 2% risk for the 10th percentile to 18% risk for the 90th percentile for well‐calibrated models. Models showed highly variable discrimination across organizations (AUC 0.571–0.842).ConclusionsWe found that EHR‐based predictive models could estimate the risk of future COU among patients with OA to help inform care decisions. Black‐box methods did not have significant advantages over more interpretable models. Care should be taken when extending all models into organizations not included in model training because of a high variability in performance across held‐out organizations.
Data‐Driven Magnetic Resonance Imaging Definitions for Active and Structural Sacroiliac Joint Lesions in Juvenile Spondyloarthritis Typical of Axial Disease: A Cross‐Sectional International Study
Authors: Weiss Pamela F. , Brandon Timothy G. , Lambert Robert G. , Biko David M. , Chauvin Nancy A. , Francavilla Michael L. , Jaremko Jacob L. , Herregods Nele , Kasapcopur Ozgur , Yildiz Mehmet , Hendry Alison M. , Maksymowych Walter P. 
Published: September 2022

ObjectiveWe aimed to determine quantitative sacroiliac (SI) joint magnetic resonance imaging (MRI) cutoffs for active and structural lesions that will be incorporated as imaging domains in classification criteria of axial disease in juvenile spondyloarthritis (SpA).MethodsMRI scans from an international cross‐section of juvenile SpA patients were reviewed by 6 musculoskeletal imaging experts blinded to clinical details. Raters globally assessed the presence/absence of lesions typical of axial SpA and performed SI joint quadrant‐ or joint‐based scoring. Sensitivity and specificity of lesion cutoffs were calculated using a rater majority (≥4 of 6 raters) on a global assessment of the presence/absence of active or structural lesions typical of axial SpA with high confidence as the reference standard. Cutoffs were validated in an independent cohort.ResultsImaging from 243 subjects, 61% male, median age 14.9 years, had sequences available for detailed MRI scoring. Optimal cutoffs for defining lesions typical of axial disease in juvenile SpA were: 1) inflammatory lesion: bone marrow edema in ≥3 SI joint quadrants across all SI joint MRI slices (sensitivity 98.6%, specificity 96.5%); 2) structural lesions: erosion in ≥3 quadrants or sclerosis or fat lesion in ≥2 SI joint quadrants or backfill or ankylosis in ≥2 joint halves across all SI joint MRI slices (sensitivity 98.6%, specificity 95.5%). Sensitivity and specificity of the optimal cutoffs in the validation cohort were excellent.ConclusionWe propose data‐driven cutoffs for active inflammatory and structural lesions on MRI typical of axial disease in juvenile SpA that have high specificity and sensitivity using central imaging global assessment as the reference standard and excellent reliability.
Motion Artifact‐Resilient Zone for Implantable Sensors
Authors: Jeong Chanho , Koirala Gyan Raj , Jung Yei Hwan , Ye Yeong Sinn , Hyun Jeong Hun , Kim Tae Hee , Park Byeonghak , Ok Jehyung , Jung Youngmee , Kim Tae‐il 
Published: September 2022

AbstractThe miniaturization and flexibility of wearable and implantable devices allow humans to carry them directly on or in their bodies, thus enabling these devices to measure biometric signals in real‐time anywhere. However, as they are embedded or implanted into an actively moving human interface, motion artifact noise inevitably occurs. Typically, devices are laminated or implanted on body surfaces, but the positions of such devices cannot be designed without any discussion of the noise. Thus, this paper investigates an approach that minimizes the noise to achieve negligible motion artifacts in implantable micro‐devices that have a specific angle on the surface of the body, while maintaining the function of sensor. The device with a specific angle successfully detects the target signal, while motion artifacts—such as tension, compression, and bending—disturb the measurement. The pulse signal on a wrist is well measured while the hand is rotating, and artificial skin implanted on a rat can distinguish external pressure from the movement noise. A thermometer sensor that follows the same rule is further examined. Therefore, this approach is expected to be useful in numerous areas including human interface‐based medical devices, virtual reality, and health aids to improve quality of life.