bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autonomy-supportive decision-making in maternity care during prenatal consultations: a qualitative interaction analysis
Authors: Kors Joyce , de la Croix Anne , Martin Linda , Verhoeven Corine J M , Bakker Petra , Peerdeman Saskia M , Kusurkar Rashmi A 
Published: November 2022

ObjectivesThe aim of this study was to identify mechanisms of autonomy-supportive consultation (ASC) that maternity care professionals use during decision-making in prenatal consultations.DesignThis study was a descriptive, qualitative analysis of professional–patient interactions in maternity care, using concepts and analytic procedures of conversation analysis.SettingThe prenatal consultations took place in hospitals and midwifery practices in the Netherlands. This study was part of a larger project. For the current study, we selected prenatal consultations concerning three topics in which patients make their own choices.ParticipantsThe first author invited the patient who was waiting in the waiting room. Participants were not selected a priori.Main outcome measuresThe main outcome measures were mechanisms of ASC.ResultsWe selected 20 consultations which were conducted by 20 different professionals. We found eight mechanisms in the professional–patient interaction which were categorised into three overarching themes. The first theme, ‘Lightheartedness’, comprises the interactional mechanisms ‘minimising language’ and ‘humour’. The theme ‘Orientation to agreement’ describes how professionals and patients seem to be oriented towards demonstrating agreement and mutual understanding. The last theme, ‘Offering information and options’, describes the professional formally giving factual information almost completely without verbal interaction between the professional and the patient.ConclusionThe results of this study show that the model of ASC can be enriched by adding minimising language and humour to the mechanisms that can be used to fulfil the psychological need ‘relatedness’. Second, our results show that professionals use only few mechanisms to meet the patients’ psychological needs ‘competence’ and ‘autonomy’. They mainly use information giving to meet patients’ need competence. To meet patients’ need for autonomy, the professionals keep all options open. This suggests that professionals could pay more attention to other mechanisms to meet patients’ needs for ‘competence’ and ‘autonomy’.
Cross-sectional associations between neighbourhood walkability and objective physical activity levels in identical twins
Authors: Duncan Glen E , Avery Ally A , Hurvitz Philip , Vernez-Moudon Anne , Tsang Siny 
Published: November 2022

ObjectivesPhysical activity is a cornerstone of chronic disease prevention and treatment, yet most US adults do not perform levels recommended for health. The neighborhood–built environment (BE) may support or hinder physical activity levels. This study investigated whether identical twins who reside in more walkable BEs have greater activity levels than twins who reside in less walkable BEs (between-twin analysis), and whether associations remain significant when controlling for genetic and shared environmental factors (within-twin analysis).DesignA cross-sectional study.SettingThe Puget Sound region around Seattle, Washington, USA.ParticipantsThe sample consisted of 112 identical twin pairs who completed an in-person assessment and 2-week at-home measurement protocol using a global positioning system (GPS)monitor and accelerometer.ExposureThe walkability of each participants’ place of residence was calculated using three BE dimensions (intersection density, population density and destination accessibility). For each variable, z scores were calculated and summed to produce the final walkability score.OutcomesObjectively measured bouts of walking and moderate-to-vigorous physical activity (MVPA), expressed as minutes per week.ResultsWalkability was associated with walking bouts (but not MVPA) within the neighbourhood, both between (b=0.58, SE=0.13, p<0.001) and within pairs (b=0.61, SE=0.18, p=0.001). For a pair with a 2-unit difference in walkability, the twin in a more walkable neighbourhood is likely to walk approximately 16 min per week more than the co-twin who lives in a less walkable neighbourhood.ConclusionsThis study provides robust evidence of an association between walkability and objective walking bouts. Improvements to the neighbourhood BE could potentially lead to increased activity levels in communities throughout the USA.
Electronic patient-reported outcome measures to enable systematic follow-up in treatment and care of women diagnosed with breast cancer: a feasibility study protocol
Authors: Thestrup Hansen Stine , Piil Karin , Bak Hansen Lone , Ledertoug Karen Marie , Hølge-Hazelton Bibi , Schmidt Volker Jürgen 
Published: November 2022

IntroductionThe use of patient-reported outcome measures (PROMs) in clinical practice has the potential to promote person-centred care and improve patients’ health-related quality of life. We aimed to develop an intervention centred around electronic PROMs (ePROMs) for systematic follow-up in patients diagnosed with breast cancer and to evaluate its feasibility.Methods and analysisWe developed a nurse-oriented and surgeon-oriented intervention in PROMs, including (1) an education programme for nurses and surgeons; (2) administration of BREAST-Q as proactive ePROMs during follow-up in patients diagnosed with breast cancer and (3) feedback to nurses and surgeons on PROM scores and a guidance manual for healthcare practitioners. Subsequently, we designed a non-controlled feasibility evaluation on the outcomes acceptability, demand, implementation, practicality and integration. The feasibility evaluation includes qualitative ethnographic studies exploring the user perspectives of patients, nurses and surgeons and quantitative studies to explore the characteristics of the patient population regarding demographic background, response rates and response patterns. The feasibility study was initiated in September 2021, will continue until 2024 and will include approximately 900 patients. EPROMs are collected at the following assessment time points: baseline (after diagnosis, before surgery), 1-year follow-up and 3-year endpoint.Ethics and disseminationThe study will be conducted according to the General Data Protection Regulation and the fifth version of the Helsinki Declaration. The National Committee on Health Research Ethics approved the study according to the law of the Committee § 1, part 4. All data will be anonymised before its publication. The results of the feasibility study will be published in peer-reviewed, international journals.
Increasing COVID-19 testing and vaccination among Spanish speakers in the USA: protocol for the development and evaluation of theNuestra Comunidad Saludableintervention using a group-randomised trial design
Authors: Rhodes Scott D , Tanner Amanda E , Mann-Jackson Lilli , Alonzo Jorge , Hall Mark A , Bertoni Alain G , McCoy Thomas P , Aguilar-Palma Sandy K , Garcia Manuel , Miranda Daniela , Turner Mari Jo 
Published: November 2022

IntroductionOur community-based participatory research partnership aims to expand understanding of the social, ethical and behavioural implications of COVID-19 testing and vaccination to inform the development of an integrated intervention that harnesses community-based peer navigation and mHealth strategies to improve COVID-19 testing and vaccination; test the intervention; and develop and disseminate practice, research and policy recommendations to further increase COVID-19 testing and vaccination among Spanish-speaking Latine communities in the USA.Methods and analysisWe will conduct 50 individual in-depth interviews with health providers, who have conducted COVID-19 testing and/or vaccination activities within Spanish-speaking communities, and with representatives from Latine-serving community-based organisations. We will also conduct six focus groups with 8–12 Spanish-speaking Latine community member participants each for a total number of about 60 focus group participants. Next, we will develop theNuestra Comunidad Saludableintervention based on findings from interviews and focus groups and use a longitudinal group-randomised trial design with two arms (intervention and delayed intervention) to evaluate the impact of the intervention. We will recruit, enrol and collect baseline data from 20 community-based peer navigators (Navegantes) and their social network members (n=8 unique social network members perNavegante).Navegantes(coupled with their social networks) will be randomised to intervention or delayed intervention groups (10Navegantesand 80 social network members per group).Ethics and disseminationEthical approval for data collection was granted by the Wake Forest University School of Medicine Institutional Review Board. Following the description of study procedures, we will obtain consent from all study participants. Study findings will be disseminated through an empowerment theory-based community forum, peer-reviewed publications and presentations at scientific meetings, and reports and briefs for lay, community and practitioner audiences.Trial registration numberNCT05302908.
Improving experience of medical abortion at home in a changing therapeutic, technological and regulatory landscape: a realist review
Authors: Baraitser Paula , Free Caroline , Norman Wendy V , Lewandowska Maria , Meiksin Rebecca , Palmer Melissa J , Scott Rachel , French Rebecca , Wellings Kaye , Ivory Alice , Wong Geoff 
Published: November 2022

ObjectiveTo inform UK service development to support medical abortion at home, appropriate for person and context.DesignRealist reviewSetting/participantsPeer-reviewed literature from 1 January 2000 to 9 December 2021, describing interventions or models of home abortion care. Participants included people seeking or having had an abortion.InterventionsInterventions and new models of abortion care relevant to the UK.Outcome measuresCausal explanations, in the form of context-mechanism-outcome configurations, to test and develop our realist programme theory.ResultsWe identified 12 401 abstracts, selecting 944 for full text assessment. Our final review included 50 papers. Medical abortion at home is safe, effective and acceptable to most, but clinical pathways and user experience are variable and a minority would not choose this method again. Having a choice of abortion location remains essential, as some people are unable to have a medical abortion at home. Choice of place of abortion (home or clinical setting) was influenced by service factors (appointment number, timing and wait-times), personal responsibilities (caring/work commitments), geography (travel time/distance), relationships (need for secrecy) and desire for awareness/involvement in the process. We found experiences could be improved by offering: an option for self-referral through a telemedicine consultation, realistic information on a range of experiences, opportunities to personalise the process, improved pain relief, and choice of when and how to discuss contraception.ConclusionsAcknowledging the work done by patients when moving medical abortion care from clinic to home is important. Patients may benefit from support to: prepare a space, manage privacy and work/caring obligations, decide when/how to take medications, understand what is normal, assess experience and decide when and how to ask for help. The transition of this complex intervention when delivered outside healthcare environments could be supported by strategies that reduce surprise or anxiety, enabling preparation and a sense of control.
Implementation of a mailed faecal immunochemical test programme for colorectal cancer screening among Veterans
Authors: Deeds Stefanie Ann , Moore Christopher B , Gunnink Eric J , Wheat Chelle L , Robinson Amy E , Bomsztyk Mayan D , Geyer John R , Chen Anders , Godbout Regina M , Nelson Karin M , Dominitz Jason A , Reddy Ashok 
Published: November 2022

BackgroundScreening for colorectal cancer (CRC) with faecal immunochemical test (FIT) is effective at reducing CRC mortality. Unfortunately, the COVID-19 pandemic has been associated with deferred care, especially screening for CRC.AimWe sought to develop a mailed FIT programme (MFP) to increase CRC screening and make recommendations for adoption across the Veterans Health Administration (VHA) and for other large healthcare systems.Setting2 regional VA medical centres in California and Washington state.Participants5667 average risk veterans aged 50–75 overdue or due within 90 days for CRC screening.Programme descriptionA multidisciplinary implementation team collaborated to mail an FIT kit to eligible veterans. Both sites mailed a primer postcard, and one site added an automated reminder call.Programme evaluationWe monitored FIT return and positivity rate, as well as impact of the programme on clinical staff. 34% of FIT kits were returned within 90 days and 7.8% were abnormal.DiscussionWe successfully implemented a population-based MFP at multiple regional VA sites and recommend that these efforts be spread across VA. Our model of regional leadership, facility champions and using centralised resources can be adaptable to other large healthcare systems. MFPs support catch-up from disrupted care by addressing access to CRC screening, unburden primary care visits and conserve limited procedural resources.
Parental death: a systematic review of support experiences and needs of children and parent survivors
Authors: Wray Alexandra , Pickwell-Smith Benjamin , Greenley Sarah , Pask Sophie , Bamidele Olufikayo , Wright Barry , Murtagh Fliss , Boland Jason W 
Published: November 2022

BackgroundBereaved people need a supportive response from those around them. Knowing children’s and surviving parents' needs following parental death is the first step to ensuring a supportive response. However, no systematic review has reported on this phenomenon.AimTo systematically identify and synthesise qualitative literature exploring support experiences of parentally bereaved children and surviving parents.MethodsSystematic review with thematic synthesis, following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. MEDLINE, Embase, PsycINFO, CINAHL and the British Nursing Database were searched for relevant papers to September 2021. Included studies were appraised for quality and thematically synthesised using Thomas and Harden’s thematic synthesis framework.ResultsFifteen qualitative studies from nine countries were included. There were four analytical themes from the children’s perspectives (1) Openness of communication with children about death and dying, (2) Children’s challenges of managing change, (3) Navigating emotions, and (4) Children’s acceptability, access and engagement with support. There were three analytical themes from the parents' perspectives: (1) Adjusting as a parent, (2) Supporting their children, and (3) Parent’s acceptability, access and engagement with support.ConclusionsFollowing a parental death, open and honest communication and involvement in what is happening within the family will help children cope. Both children and parents suppress emotions and avoid conversations to protect each other and those around them. A taboo around death exists and constrains the support some families receive. Childhood bereavement is a public health issue, with a need for professionals and communities to better understand and respond to the needs of bereaved families.CRD42020166179
Higher form Yang–Mills as higher BFYM theories
Authors: Song Danhua , Lou Kai , Wu Ke , Yang Jie 
Published: November 2022

AbstractThe YM theory has been generalized to 2YM and 3YM theories. Similarly, we generalize the BFYM theory to “2BFYM” and “3BFYM” theories. Then, we show that these higher BFYM theories can give the formulations of the corresponding higher form YM theories. Finally, we study the gauge symmetries of these higher BFYM theories.
On Araki’s extension of the Jordan–Wigner transformation
Authors: Aschbacher Walter H. 
Published: November 2022

In his seminal paper [On the XY-model on two-sided infinite chain, Publ. RIMS Kyoto Univ. 20 (1984) 277–296], Araki introduced an elegant extension of the Jordan–Wigner transformation which establishes a precise connection between quantum spin systems and Fermi lattice gases in one dimension in the so-called infinite system idealization of quantum statistical mechanics. His extension allows in particular for the rigorous study of numerous aspects of the prominent XY chain over the two-sided infinite discrete line without having to resort to a thermodynamic limit procedure at an intermediate or at the final stage. We rigorously review and elaborate this extension from scratch which makes the paper rather self-contained. In the course of the construction, we also present a simple and concrete realization of Araki’s crossed product extension.
RIS3D: A Referenced Information System in 3D
Authors: Dutailly Bruno , Portais Jean-Christophe , Granier Xavier 
Published: November 2022

3D Geographical Information Systems (GIS), Building Information Modeling (BIM),… These words are increasingly used for Cultural Heritage studies to refer to the necessity to connect heterogeneous data with a 3D model.
In this article, we introduce and formalize the notion of RIS3D (Referenced Information System in 3D), which extends the concept of GIS to 3D supports and generalizes it. For this purpose, we propose a generic and modular client-server approach that brings the required flexibility, extendibility, and sustainability to deal with heterogeneous data. For queries and their visualization in a 3D environment, we push forward the notions of layers and markers.
We also provide the readers with our technical choices that allowed us to develop our own implementation of a RIS3D solution. We demonstrate it on a real-case scenario: the preservation of the Lascaux painted cave where our solution has been deployed and is in use.
The proposed notion and generic architecture of RIS3D, its implementation, and its deployment show the suitability of such an approach and its potential applications.
Associations of Maternal Fructosamine before Delivery in Gestational Diabetes Mellitus Pregnancies with Neonatal Glucometabolic Disorders
Authors: Mao Zhengxia , Wu Ruilin , Yu Huan , Zhang Yujiao , Dong Wenbin , Zou Lile , Lei Xiaoping 
Published: November 2022

Background. The offspring of pregnant women with gestational diabetes mellitus (GDM) are vulnerable to be glucometabolic disorders. However, to date, few current studies focused on the associations of maternal accumulated glucose exposure before delivery with neonatal glucometabolic disorders and large for gestational age (LGA) infants. This study is aimed at exploring the associations of maternal fructosamine (FMN) before delivery in GDM pregnant women with neonatal glucometabolic disorders in the first 3 days of life and LGA infants. Methods. The study subjects were the GDM pregnant women, who gave birth in our hospital from September 1, 2018 to January 31, 2021, and their newborns. The maternal FMN adjusted by serum albumin (FMNALB) before delivery was selected as exposure factors. A multivariate logistical regression model was used to calculate the odds ratios (OR) for neonatal glucometabolic disorders, hypoglycemia needing intervention (<2.6 mmol/L), and glucose intolerance (>7.0 mmol/L) in the first 3 days and LGA infants. Results. In GDM pregnant women, the newborns in the maternal

FM

N

ALB

≥
75
th

percentile

(≥5.89 mmol/g) group had higher risks in neonatal glucometabolic disorders (aOR 2.50, 95% CI 1.34-4.65,

P
=
0.004

) and hypoglycemia (aOR 2.18, 95% CI 1.16-4.10,

P
=
0.016

). However,

FM

N

ALB

≥
75
th

percentile

seemed to be not predictive of the glucose intolerance (aOR 1.76, 95% CI 0.82-3.79,

P
=
0.149

) and LGA (aOR 1.56, 95% CI 0.81-3.02,

P
=
0.185

). Further, in the sensitivity analysis, the newborns in the maternal

FM

N

ALB

≥
90
th

percentile

(≥6.40 mmol/g) group also had higher risks in neonatal glucometabolic disorders (aOR 5.70, 95% CI 2.18-14.89,

P
<
0.001

) and hypoglycemia (aOR 3.72, 95% CI 1.48-9.31,

P
=
0.005

). Conclusions. The maternal FMNALB before delivery in GDM pregnant women was a useful biomarker to identify the offspring with high risk of neonatal glucometabolic disorders. However, the association between maternal FMNALB and the risk of LGA infants was not so strong.
Reprogramming the Canine Glioma Microenvironment with Tumor Vaccination plus Oral Losartan and Propranolol Induces Objective Responses
Authors: Ammons Dylan T. , Guth Amanda , Rozental Aaron J. , Kurihara Jade , Marolf Angela J. , Chow Lyndah , Griffin John F. , Makii Rebecca , MacQuiddy Brittany , Boss Mary-Keara , Regan Daniel P. , Frank Chad , McGrath Stephanie , Packer Rebecca A. , Dow Steven 
Published: November 2022

Purpose:Malignant gliomas have a highly immune-suppressive tumor microenvironment (TME) which renders them largely unresponsive to conventional therapeutics. Therefore, the current study evaluated a therapeutic protocol designed to overcome the immune barrier by combining myeloid cell–targeted immunotherapy with tumor vaccination.Experimental Design:We utilized a spontaneously occurring canine glioma model to investigate an oral TME modifying immunotherapy in conjunction with cancer stem cell (CSC) vaccination. Dogs were treated daily with losartan (monocyte migration inhibitor) and propranolol (myeloid-derived suppressor cell depleting agent) plus anti-CSC vaccination on a biweekly then monthly schedule. Tumor volume was monitored by MRI and correlated with patient immune responses.Results:Ten dogs with histologically confirmed gliomas were enrolled into a prospective, open-label clinical trial to evaluate the immunotherapy protocol. Partial tumor regression was observed in 2 dogs, while 6 dogs experienced stable disease, for an overall clinical benefit rate of 80%. Overall survival times (median = 351 days) and progression-free intervals (median = 163 days) were comparable with prior studies evaluating surgical debulking followed by immunotherapy. Dogs with detectable anti-CSC antibody responses had an increased overall survival time relative to dogs that did not generate antibody responses (vaccine responder MST = 500 days; vaccine nonresponder MST = 218 days; P = 0.02).Conclusions:These findings suggest that combining myeloid cell–targeted oral immunotherapy with tumor vaccination can generate objective tumor responses, even in the absence of conventional therapy. Overall, this approach has promise as a readily implemented therapeutic strategy for use in patients with brain cancer.Significance:In a pilot study of 10 dogs with glioma, we found that orally administered losartan and propranolol plus vaccination induced durable tumor responses in 8 of 10 treated dogs. The immunotherapy protocol was well tolerated, without systemic or local toxicities. These findings indicate that continuous oral immunotherapy plus tumor vaccination is a promising new strategy for glioma management that can be readily applied in clinical trials.