bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cerebrospinal Fluid and Plasma Amine Profiles in Interictal Migraine
Authors: Onderwater Gerrit L. J. , van Dongen Robin M. , Harms Amy C. , Zielman Ronald , van Oosterhout Willebrordus P. J. , van Klinken Jan B. , Goeman Jelle J. , Terwindt Gisela M. , van den Maagdenberg Arn M. J. M. , Hankemeier Thomas , Ferrari Michel D. 
Published: December 2022

ObjectiveImpaired amine metabolism has been associated with the etiology of migraine, that is, why patients continue to get migraine attacks. However, evidence from cerebrospinal fluid (CSF) is lacking. Here, we evaluated individual amine levels, global amine profiles, and amine pathways in CSF and plasma of interictal migraine patients and healthy controls.MethodsCSF and plasma were sampled between 8:30 am and 1:00 pm, randomly and interchangeably over the time span to avoid any diurnal and seasonal influences, from healthy volunteers and interictal migraine patients, matched for age, sex, and sampling time. The study was approved by the local medical ethics committee. Individual amines (n = 31), global amine profiles, and specific amine pathways were analyzed using a validated ultraperformance liquid chromatography mass spectrometry platform.ResultsWe analyzed n = 99 participants with migraine with aura, n = 98 with migraine without aura, and n = 96 healthy volunteers. Univariate analysis with Bonferroni correction indicated that CSF L‐arginine was reduced in migraine with aura (10.4%, p < 0.001) and without aura (5.0%, p = 0.03). False discovery rate‐corrected CSF L‐phenylalanine was also lower in migraine with aura (6.9%, p = 0.011) and without aura (8.1%, p = 0.001), p = 0.088 after Bonferroni correction. Multivariate analysis revealed that CSF global amine profiles were similar for both types of migraine (p = 0.64), but distinct from controls (p = 0.009). Global profile analyses were similar in plasma. The strongest associated pathways with migraine were related to L‐arginine metabolism.InterpretationL‐Arginine was decreased in the CSF (but not in plasma) of interictal patients with migraine with or without aura, and associated pathways were altered. This suggests that dysfunction of nitric oxide signaling is involved in susceptibility to getting migraine attacks. ANN NEUROL 2023;93:715–728
Synthesis and characterization of novel bio‐based epoxy polymers derived from natural phenolic compound
Authors: Sudprasert Pirada , Kariya Shotaro , Ogino Kenji , Chirachanchai Suwabun , Kanehashi Shinji 
Published: December 2022

AbstractBio‐based epoxy polymer was prepared from cardanol derivatives, epoxy prepolymer and phenalkamine at room temperature without solvent. Chemical structures of cured epoxy polymers were analyzed by FT‐IR and 1H NMR spectroscopy. The drying, physical, thermal, optical, and mechanical properties of the epoxy polymers were investigated in terms of the composition of epoxy and amine compounds, molecular weight of the epoxy prepolymer, and the effect of post‐curing process. The resultant epoxy polymers showed flexible nature, thermal stability (e.g., thermal decomposition temperature of 300°C). Furthermore, the epoxy polymers possessed the anti‐microbial activity against Escherichia coli and Staphylococcus aureus The molecular weight of the epoxy prepolymer also strongly affected the drying property, suggesting that the drying time can be controlled by the molecular weight of the prepolymer. Thermal treatment of the polymers as post‐curing was effective approach to improve the hardness, thermal stability, and mechanical strength. Hence, this cardanol derivatives‐based novel epoxy polymer can be expected as highly green functional epoxy polymers for coating, film and resin applications.
Patient‐ and therapist‐rated alliance predict improvements in posttraumatic stress disorder symptoms and substance use in integrated treatment
Authors: Saraiya Tanya C. , Jarnecke Amber M. , Bauer Alexandria G. , Brown Delisa G. , Killeen Therese , Back Sudie E. 
Published: December 2022

AbstractObjectiveConcurrent Treatment of Posttraumatic Stress Disorder (PTSD) and Substance Use Disorders Using Prolonged Exposure (i.e., COPE) is an efficacious, integrated, psychotherapy that attends to PTSD and substance use disorders simultaneously. No study has examined how therapeutic alliance functions during the provision of COPE and how this compares to non‐integrated treatments, such as relapse prevention (RP) for substance use disorders. Understanding the role of alliance in COPE versus RP could inform treatment refinement and ways to enhance treatment outcomes.MethodsParticipants (N = 55 veterans) were randomized to 12, individual, weekly sessions of COPE or RP in a randomized clinical trial. Piecewise linear mixed effect models examined how mid‐treatment (1) patient‐rated alliance, (2) therapist‐rated alliance, and (3) the convergence between patient‐ and therapist‐rated alliance as measured by a difference score predicted reductions in PTSD symptoms and substance use across treatment and follow‐up periods.ResultsBoth patient‐ and therapist‐rated alliance predicted reductions in PTSD symptoms in COPE. Higher patient‐rated alliance predicted lower percent days using substances in RP. Difference score models showed higher patient‐rated alliance relative to therapist‐rated alliance scores predicted symptom reductions in COPE whereas higher therapist‐rated alliance scores relative to patient‐rated alliance scores predicted symptom reductions in RP.DiscussionPreliminary findings show a unique relationship between the rater of the alliance and treatment modalities. Patient‐rated alliance may be important in trauma‐focused, integrated treatments whereas therapist‐rated alliance may be more important in skills‐focused, substance use interventions.
Mutualisms in a warming world: How increased temperatures affect the outcomes of multi‐mutualist interactions
Authors: Magnoli Susan M. , Keller Kane R. , Lau Jennifer A. 
Published: December 2022

AbstractIn nature, plant species simultaneously interact with many different mutualistic partners. These mutualists may influence one another through direct interference or indirectly by competing for shared reward resources or through alteration of plant traits. Together, these mutualists also may combine to affect plant hosts in ways that may not be predictable based on pairwise interactions. Given that the outcome of mutualistic interactions often depends on environmental conditions, multi‐mutualist effects on one another, and their plant hosts may be affected by global changes. Here, we grew focal plants under simulated global warming conditions and manipulated the presence of partner mutualists to test how warming affects the outcome of interactions between focal plants and their partners (nitrogen‐fixing rhizobia, ant defenders, and pollinators) and interactions among these partner mutualists. We find that warming alters the fitness benefits plants receive from rhizobium resource mutualists but not ant mutualists and that warming altered plant investment in all mutualists. We also find that mutualist partners interact, often by altering the availability of plant‐produced rewards that facilitate interactions with other partners. Our work illustrates that global changes may affect some but not all mutualisms, often asymmetrically (e.g., affecting investment in the mutualist partner but not plant host benefits) and also highlights the ubiquity of interactions between the multiple mutualists associating with a shared host.
Vertically aligned nanocomposite films by self‐assembled epitaxial nucleation for super‐broadband transparent conductors
Authors: Ha Youngkyoung , MacManus‐Driscoll Judith L. , Lee Shinbuhm 
Published: December 2022

AbstractDesigning super‐broadband transparent conductors is challenging because of the exclusive nature of conductivity and infrared transmittance. Here, using a one‐step process, we created vertically aligned nanocomposite conducting films with high transparency across a super‐broad wavelength range. Vertically aligned transparent Ba3V2O8 nanocolumns with lateral ~100‐nm widths enable high transmittance (>50%, even at a 4‐μm wavelength) for all incident light and outperform that of Sn‐doped In2O3, while the conducting SrVO3 matrix retains low resistivity (<0.56 mΩ cm at room temperature). A combined study of scanning transmission electron microscopy, scattering scanning near‐field infrared microscopy, and X‐ray diffraction revealed that spontaneous phase separation of Ba3V2O8 nanocolumns in a SrVO3 matrix film occurs via self‐assembled epitaxial nucleation. Our vertically aligned nanocomposite films provide a fertile platform for next‐generation optoelectronics.
Detection of pathological response of axillary lymph node metastasis after neoadjuvant chemotherapy in breast cancer using multiphoton microscopy
Authors: Han Zhonghua , Huang Xingxin , Kang Deyong , Fu Fangmeng , Zhang Shichao , Zhan Zhenlin , Chen Jianxin , Li Lianhuang , Wang Chuan 
Published: December 2022

AbstractNeoadjuvant treatment is often considered in breast cancer patients with axillary lymph node involvement, but most of patients do not have a pathologic complete response to therapy. The detection of residual nodal disease has a significant impact on adjuvant therapy recommendations which may improve survival. Here, we investigate whether multiphoton microscopy (MPM) could identify the pathological changes of axillary lymphatic metastasis after neoadjuvant chemotherapy in breast cancer. And furthermore, we find that there are obvious differences in seven collagen morphological features between normal node and residual axillary disease by combining with a semi‐automatic image processing method, and also find that there are significant differences in four collagen features between the effective and no‐response treatment groups. These research results indicate that MPM may help estimate axillary treatment response in the neoadjuvant setting and thereby tailor more appropriate and personalized adjuvant treatments for breast cancer patients.
Fractional‐order filter‐based enhanced full state feedback control design with multi‐objective formulation using grey wolf optimization algorithm
Authors: Kumar Lalitesh , Singh Dhillon Sukhwinder , Kumar Prawendra 
Published: December 2022

AbstractA perturbed fractional‐order filter (FOF)‐based LQR control design with multiple performance indices is proposed in this paper. Three variants of the FOF‐based linear quadratic regulator (LQR) system have been proposed along with choices on the commensurate order of state feedback law. The multi‐objective problem formulation has been done with three performance objectives to address the different issues of design. The first performance index constitutes a weighted sum of ITAE (Integral Time of Absolute Error) and the difference between the eigenvalues of the plant and the LQR controlled plant, chosen to minimize the large oscillations as well as relative stability with respect to eigenvalues. A new lower bound of the singular values have been addressed to ensure the robust stability of the system through the formulation of a second performance objective. It is the minimization of singular values of the return ratio matrix at the plant's input. The third and the last performance index aims minimization of maximum singular values of the perturbation transfer function at the plant's output, so as to guarantee no closed‐loop right half plane zeros. The multi‐objective optimization problem is solved and the optimal solutions are obtained via Grey Wolf Optimization Algorithm. The simulation results validate the performance and effectiveness of the proposed control design.
Transition from intensive care unit to a portable ventilator in children with severe bronchopulmonary dysplasia
Authors: McKinney Robin L. , Agarwal Amit 
Published: December 2022

AbstractAs the population of ventilator‐dependent children (VDC) with tracheostomies due to underlying severe bronchopulmonary dysplasia grows, there is an increasing need to shift the care of these children from hospital to home. Transitioning the ventilator‐dependent child from the hospital to home is a complex process that requires coordination between the medical team and the family. One crucial step in the process is transitioning from an Intensive care unit (ICU) ventilator to a portable home ventilator (PHV). The Clinical team needs to understand the nuances in transitioning to PHV, including assessing readiness to transition and choosing the optimum settings on an available home ventilator. In recent years, various ventilator modes have been available in PHV that can help achieve synchronous breathing to allow for adequate gas exchange for the infant. This review details some approaches to asses readiness to transition and the process of Transition along with commonly used modes of support available in PHV, as well as the primary and secondary settings in which we should be mindful in supporting a child with chronic respiratory failure in the home setting.
Children with medical complexity and pediatric palliative care: Data by a respiratory intermediate care unit
Authors: Caggiano Serena , Pavone Martino , Cherchi Claudio , Paglietti Maria Giovanna , Schiavino Alessandra , Petreschi Francesca , Chiarini Testa Maria Beatrice , Cutrera Renato 
Published: December 2022

AbstractPediatric palliative care (PPC) is an active and total approach to the care of children with life‐limiting conditions and their families. PPC programs provide ongoing treatment for children with medical complexity (CMC), many of whom will reach adulthood. Aim of the study was to describe a population of CMC attendingin six preselected months the Respiratory Intermediate Care Unit of a tertiary referral hospital for southern and central Italy. We enrolled all CMC patients admitted to our unit in six preselected months and registered pathologies and different categories of childhood diseases, devices and needs, hospitalization and home care plan. Among the 275 children admitted to our unit, 130 CMC were included. Median age was 9.9 (0.1–40.0) years. The main pathologies recorded were neuromuscular, neurological, respiratory, metabolic and malformative diseases, genetic syndromes and outcomes of prematurity. Comorbidity due to respiratory, digestive, neurological, cardiac and urological involvement was present in a high percentage of cases. Among our patients, only 46 were not carriers of any medical device. The average length of hospitalization was 7.0 (1.0–270.0) days with 2 (1.0–7.0) admissions per year per patient. Home care activation was not required for 47 out of 130 patients. Children eligible for PPC are increasing and their survival results in a rise of comorbidities and special needs demanding multilevel interventions. Respiratory symptoms are the most recurrent ones observed, thus requiring an expert in PPC with expertise in the respiratory field. Sharing data and knowledge of CMC needs may help improve care coordination.
Isolated unilateral absence of pulmonary artery (IUAPA) in adults: A case series and review of literature
Authors: Loo Yi Jia , Thomas Rajesh , Yagnik Lokesh 
Published: December 2022

AbstractUnilateral Absence of Pulmonary Artery (UAPA) is a rare congenital malformation that is usually associated with cardiac anomalies. When there is no congenital cardiac abnormality it is rarer still and is termed isolated unilateral absence of pulmonary artery (IUAPA) (4). IUAPA may remain undetected until adulthood and frequently found incidentally on imaging for other indications. Symptoms are usually secondary to complications which include pulmonary hypertension, recurrent respiratory tract infections, bronchiectasis and haemoptysis. We report two cases with widely contrasting presentation and trajectories, leading to individualized management strategies.
Patterns and Predictors of Stranger Rape Locations
Authors: Lundrigan Samantha , Weir Ruth , Newton Andrew , Agudelo Kelly , Dhami Mandeep 
Published: December 2022

AbstractThis paper examines the spatial, environmental, and temporal patterns of 10,488 stranger rapes committed over a 15-year period in Greater London, UK. We distinguished between two types of stranger rapes according to perpetrator method of approach, i.e. absent/fleeting interaction with victim on approach (S1) or extended interaction with victim on approach (S2). There were a range of locational settings in which perpetrators both encountered their victims and where the offence took place, and these differed by method of approach. The highest number of S1 offences occurred outdoors, with 74% of approaches and 55% of offences located recorded as outside. For S2 rapes, there was more variety in approach locations with only 32% outside. The level of locational correspondence between approach and offence location was 71% for S1 rapes and 28% for S2 rapes. A series of negative binomial regression models identified variables predictive of stranger rape offence location. There were significant associations with transport connections and the night-time economy for both S1 and S2 rapes. Other significant predictors were deprivation score, the percentage of one person properties, and the percentage of private rented properties in a location. The percentage of green space was a significant predictor for S1 rapes only. The current findings challenge the popular narrative that stranger rape occurs in a specific setting (i.e. outside in a secluded location at night) and have implications for place-based crime prevention policy.
Analysis of Visual Characteristics of Short-circuited Arc Sites
Authors: Hong Seongjun , Bang Sun-bae , Bang Jun-ho , Park Jinyoung , Min Ki-deuk , Lee Jin-sik 
Published: December 2022

AbstractIdentifying the cause of fire at a fire site is an important fire prevention measure to prevent recurrence. In particular, information about molten marks of the copper wire is essential to check whether electric power is being supplied at the fire site. This study aims to analyse the visual characteristics of arc sites formed by a short circuit to identify the molten marks at the fire site. When a short circuit occurs, electromagnetic force is generated by the short circuit current, and the arc repulsion force is generated by the contact arc. In this study, the effects of the forces, which act on the short-circuited melted area, on the formation of copper molten marks were investigated. Copper molten marks formed by a short circuit were experimentally fabricated, and the visual characteristics based on the force that was applied to the melted area were identified and classified based on features. The results showed that the melted area was affected by both the arc repulsion and electromagnetic forces, resulting in the visual differences between the short-circuited arc sites and flame-melted ones, which are affected by gravity and molecular force. These results provide a theoretical basis for discriminating between arc sites formed by a short circuit and flame-melted marks at the fire site. The validity of this study was verified via a comparative analysis using shape and cross-sectional microstructure of molten marks collected at the fire site.
Potential to improve nitrogen use efficiency (NUE) by use of perennial mobile green manures
Authors: Ward C. R. , Chadwick D. R. , Hill P. W. 
Published: December 2022

AbstractSupplying nitrogen (N) to crops by incorporating N2-fixing green manures into soil can improve soil functioning and increase soil carbon storage. However, as with N-fertiliser use, excess mineral N from decomposed green manures can be lost via leaching as NO3− and emitted as the greenhouse gas N2O. To improve nitrogen use efficiency (NUE) we propose supplying leaf matter harvested from permanent stands of N2-fixing plants grown ex-situ as perennial mobile green manures (PMGMs), thus allowing flexible timing of additions to synchronise with N demand. To assess the effectivity of PMGM use, we monitored crop N uptake, biomass production and soil mineral N from fertilisation by three potential PMGM species, Alnus glutinosa (alder), Gunnera tinctoria (gunnera), and Ulex europaeus (gorse), compared to the conventional green manure Trifolium pratense (red clover) and NH4NO3 fertiliser. Effectivity of N fertilisation by PMGMs increased with the duration of their use. In the first season of a field experiment, crop N uptake after addition of 200 kg N ha−1 within gunnera was equivalent to that from only 14 kg NH4NO3-N ha−1, but after two yearly harvests with annual gunnera additions it increased to 70 kg NH4NO3-N ha−1 year−1 equivalent. In a 1-year pot experiment, PMGMs resulted in equal or higher crop biomass than clover-fed crops, with lower soil NO3− (≤ 25 mg N L−1 soil solution) than in clover-treated soil (≥ 130 mg N L−1). We conclude that PMGMs have potential to increase NUE over that of traditional green manures and discuss the feasibility and possible agro-ecological benefits of PMGM-fed systems.
Examining the Relationship of Clergy Distress, Spiritual Well-Being, Stress Management and Irritation to Life Satisfaction among Black Pastors in the USA
Authors: Rogers Robert C. 
Published: December 2022

AbstractThis study sought to determine the level of clergy distress and other psychological characteristics of Black pastors and their relationship to life satisfaction through a convenience sample of 2786 Black pastors in historically Black Protestant denominations and nondenominational Black churches. The response rate equaled 10.1% (283/2786) while the survey completion rate equaled 77% (218/283). These 218 Black pastors were serving as either senior pastors (86.3%) or co-pastors (13.7%). This study found clergy distress in Black pastors did not differ based on gender or age but differed by church size and denomination. Clergy distress (r =  − .187, p = .023) and irritation (r =  − .293, p = .003) possessed significant relationships with satisfaction with life as expected, but stress management (r = .039, p = .641), spiritual well-being in daily life (r = .140, p = .140), and spiritual well-being in ministry (r =  − .064, p = .475) did not, which was surprising. Notably strong relationships existed between stress management and spiritual well-being in daily life (r = .469, p = .003) and stress management and irritation (r =  − .359, p = .003). These two important relationships may offer some guideposts for Black pastors in developing strategies to combat the impact of both clergy distress and irritation. The study concludes with implications for Black pastors and suggestions for future research.
The lattice of one-sided congruences on an inverse semigroup
Authors: Brookes Matthew D. G. K. 
Published: December 2022

AbstractWe build on the description of left congruences on an inverse semigroup in terms of the kernel and trace due to Petrich and Rankin. The notion of an inverse kernel for a left congruence is developed. Various properties of the trace and inverse kernel are discussed, in particular that the inverse kernel is a full inverse subsemigroup and that both the trace and inverse kernel maps are onto$$\cap $$∩-homomorphisms. It is shown that a left congruence is determined by its trace and inverse kernel, and the lattice of left congruences is identified as a subset of the direct product of the lattice of congruences on the idempotents and the lattice of full inverse subsemigroups. We demonstrate that every finitely generated left congruence is the join of a finitely generated trace minimal left congruence and a finitely generated idempotent separating left congruence. Characterisations are given of inverse semigroups that are left Noetherian, or are such that Rees left congruences are finitely generated.