bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coisotropic Branes on Tori and Homological Mirror Symmetry
Authors: Qin Yingdi 
Published: October 2022

Abstract
Homological mirror symmetry (HMS) asserts that the Fukaya category of a symplectic manifold is derived equivalent to the category of coherentsheaves on the mirror complex manifold. Without suitable enlargement (split closure) of the Fukaya category, certain objects of it are missing to prevent HMS from being true. One possible solution is to include coisotropic branes into the Fukaya category. This paper gives a construction for linear symplectic tori of a version of Fukaya category including coisotropic branes by using a doubling procedure, and discussing the relation between the Fukaya category of the doubling torus and the Fukaya category of the original torus.
“We are the ones who will have to make the change”: Cuban health cooperation and the integration of Cuban medical graduates into practice in the Pacific
Authors: McLennan Sharon , Werle Cristine 
Published: October 2022

Abstract

Background:This paper responds to Asante et al (2014), providing an updated picture of the impacts of Cuban medical training in the Pacific region based on research carried out in 2019-2021, which focused on the experiences of Pacific Island doctors trained in Cuba and their integration into practice in their home countries.Methods:The research focussed on two case studies – the Solomon Islands and Kiribati. Study methods for this research included multi-sited ethnographic methods and semi-structured interviews as well as qualitative analysis of policy documents, reports, and media sources.Results:The Cuban programme has had a significant impact on the medical workforce in the region increasing the number of doctors employed by Pacific Ministries of Health between 2012 and 2019. Qualitatively, there have been some notable improvements in health delivery over this period. However, the integration of the Cuban-trained doctors into practise has been challenging, with criticisms of their clinical, procedural and communication skills, and the need for the rapid development of bridging and internship training programmes (ITPs)which were inadequately planned for at the outset of the programme.Conclusions:The Cuban programme in the Pacific is an important model of development assistance for health in the region. While Cuba’s offer of scholarships was the trigger for a range of positive outcomes, the success of the programme has relied on input from a range of actors including support from other governments and institutions, and much hard work by the graduates themselves, often in the face of conservable criticism. Key impacts of the programme to date include the raw increase in the number of doctors and the development of the ITPs and career pathways for the graduates, although this has also led to the reorientation of Cuban graduates from preventative to curative health. There is considerable potential for these graduates to contribute to improved health outcomes across the region, particularly if their primary and preventative health care skills are utilised.
Impact of Pre-exposure Prophylaxis (PrEP) on sexually transmitted infection (STI) incidence among men who have sex with men (MSM) in Mecklenburg County North Carolina.
Authors: Omerhi Isaiah , Burks LaQuisha 
Published: October 2022

Abstract
Impact of Pre-exposure Prophylaxis (PrEP) on sexually transmitted infection (STI) incidence among men who have sex with men (MSM) in Mecklenburg County North Carolina
Objective: This study aims to determine whether MSM who were prescribed Truvada for pre-exposure prophylaxis (PrEP) have a higher incidence of sexually transmitted infections (STIs) than MSM not using Truvada for PrEP.
Design: Primary analysis of longitudinal STI data obtained from MSM attending Rosedale Medical and Amity Medical Group in Charlotte North Carolina, USA, and January 2016–October 2018.
Methods: Men who have sex with men (MSM) individuals were identified and grouped into two, those who were prescribed PrEP and a second group not using PrEP (propensity score was used to match similar individuals). Patients' STI data was used to compare the incidence of chlamydia, gonorrhea, and syphilis, and time to first symptomatic STI among PrEP users and nonusers.
Results: Propensity score matched 98 PrEP users to nonusers included in the analysis. Incidence rate ratios (IRRs) for chlamydia, gonorrhea and early syphilis were 3.2 [95% confidence interval (95% CI): 1.9–5.3], 2.8 (95% CI: 1.7–4.6) and 2.9 (95%CI: 1.5–5.6), respectively, comparing PrEP users to nonusers. Time to first symptomatic STI was shorter among PrEP users (120 days, 95% CI: 77–171) than among nonusers (185 days, 95% CI: 163–256).
Conclusion: Among MSM on PrEP, we observed a higher incidence of STIs and faster time to first symptomatic STI than MSM, not on PrEP. PrEP nonusers had a higher incidence of syphilis compared to PrEP users. However, there is insufficient evidence that PrEP maybe a contributing factor in increasing STI rates among MSM.
Isovists compactness and stairs as predictors of evacuation route choice
Authors: Snopková Dajana , De Cock Laure , Juřík Vojtěch , Kvarda Ondřej , Tancoš Martin , Herman Lukáš , Kubíček Petr 
Published: October 2022

Abstract
The building design is a crucial factor that can be actively adjusted and optimized to prevent human and property threats in emergency scenarios. Previous research suggests that specific building layouts may significantly influence human behaviour during evacuation. However, detailed empirical data about human behaviour in various types of buildings with different layouts are still missing and only marginal recommendations from this field are reflected in actual construction practice. In this study, desktop VR technologies were employed to study human decision-making in problematic T-intersections in the context of an emergency evacuation. More specifically, we studied fundamental attributes of buildings such as the width and length of the corridors and the presence of stairs to explore how they influence the choice of the evacuation route. The space-syntax isovist method was used to describe spatial parameters of corridors, which makes the results applicable to all buildings. Behavioural data from 208 respondents were analysed using multilevel regression models. Our results support previous claims concerning the importance of specific spatial layouts of evacuation corridors because respondents systematically chose wider and shorter corridors with visible staircases as the preferred evacuation route. The present findings further promote the ongoing discussion on the design of marked evacuation routes and building design that takes human factors into consideration.
Hydrogeochemical Characterization and Analysis of the Relation between Underground Oil Storage Caverns Construction and Hydro-environment
Authors: Wang Zhechao , Li Cheng , Qiao Liping , Zhong Shengran 
Published: October 2022

Abstract
Hydrogeochemical environment is of critical importance for the environment-friendly operation of underground oil storage caverns. The construction of underground oil storage caverns usually has an impact on the hydro-environment. The characterization and analysis of the hydrogeochemical environment can provide information on the relation between construction and hydro-environment. The quality of water samples was detected and analyzed to determine the chemical type in an underground oil storage cavern in China. The water samples are classified using principal component analysis and cluster analysis. The source and proportion of seepage water into the storage caverns are determined with end member mixing calculation. The results show that the chemical type of groundwater is mainly HCO3 + Cl − Na type, and the two dominant factors affecting the evolution of hydrogeochemical content are rock dissolution and groundwater seepage. All water samples can be catalogued as seepage water, water curtain water, X River water and background water. The water curtain water can fully penetrate into the ground to provide containment for the storage caverns, and the water curtain system has a good performance and can basically cover the project area. Most of the seepage water into the storage caverns comes from water curtain water and X River water, while the proportion of background water is relatively low. The construction of underground oil storage caverns affects the groundwater flow regime by changing the directions of groundwater flow around the caverns. This study showcases the use of hydrogeochemical analysis in depicting the interplay between surface water and groundwater for underground rock engineering.
Biological clock genes are crucial and promising biomarkers for the therapeutic targets and prognostic assessment in gastric cancer
Authors: Tian Yonggang , Xie Yunqian , Bai Feihu , Zhang Dekui 
Published: October 2022

Abstract

Background: Gastric cancer is one of the major public health problems worldwide. Circadian rhythm disturbances driven by circadian clock genes play a role in the development of cancer. However, whether circadian clock genes can serve as potential therapeutic targets and prognostic biomarkers for gastric cancer remains elusive.
Methods: In this study, we comprehensively analyzed the potential relationship between circadian clock genes and gastric cancer using online bioinformatics databases such as GEPIA, cBioPortal, STRING, GeneMANIA, Metascape, TIMER, TRRUST, and GEDS.
Results: Biological clock genes are expressed differently in human tumors. Compared with normal tissues, only PER1, CLOCK and TIMELESS expression differences were statistically significant in gastric cancer (p<0.05). PER1(P=0.0169) and CLOCK (P=0.0414) were associated with gastric cancer pathological stage (p<0.05). Gastric cancer patients with high expression of PER1 (p=0.0028) and NR1D1 (p=0.016) had longer overall survival, while those with high expression of PER1 (p=0.042) and NR1D1 (p=0.016) had longer disease-free survival. The main function of the biological clock gene is related to the circadian rhythm and Melatonin metabolism and effects. CLOCK, NPAS2 are KAT2B were a key transcription factor for circadian clock genes. In addition, we also found important correlations between circadian clock genes and various immune cells in the gastric cancer microenvironment.
Conclusions：This study may establish a new gastric cancer prognostic indicator based on the biological clock gene and develop new drugs for the treatment of gastric cancer using biological clock gene targets.
Supramolecular Assembly of Guanidinium benzilate and Benzylammonium benzilate — Structural and Spectroscopic (FT-IR, UV-Vis and Photoluminescence) Analyses
Authors: Sankar Nivithaa , Sudharsanan Nishanth , Seetharamiah Nagaraja Karachalacherevu , Chandran Karnan 
Published: October 2022

Abstract

Guanidinium benzilate (GBA) and benzylammonium benzilate (BABA) have been prepared from guanidinium carbonate and benzylamine/benzilic acid. GBA has interionic, intraionic, and intermolecular hydrogen bondings giving a three-dimensional supramolecular assembly. The carboxylate ion is present in the resonance form with C-O distances are of 1.242 and 1.246Å in GBA, whereas in non-resonance form with C-O distances of 1.262 and 1.245Å in BABA. In BABA, an inverted dimer with inter ionic hydrogen bonding exist as a dimer with supramolecular assembly due to intermolecular hydrogen bonding between the ion pairs. So the counter cation decides the resonance form of the carboxylate ion, hydrogen bonding network and the disposition of the phenyl rings in the benzilate and benzyl moiety. The IR,1H NMR and13C NMR spectral data have been interpreted using the crystal structure data and by the comparison between the two similar derivatives. Both the compounds exhibit the emission at 442 nm (Blue) and 547.2 nm (Green) on excitation. Chromaticity indicated excellent emission characteristics of both GBA and BABA which is necessary for OLED applications.
Atosiban application in fresh embryo transfer cycle is effective for women undergoing repeated embryo implantation failures, especially for advanced-age obese patients
Authors: Li Jie , Lin Zhong , Chen Yang , Shi Qiuling 
Published: October 2022

Abstract
Objectives
To understand the effect of atosiban in pregnancy outcomes in the fresh embryo transfer (ET).
Methods
689 cases (using atosiban) and 1377 age and embryo transfer cycle-matched controls were collected from the January 2016 to May 2022 to perform the fresh IVF-ET cycle. The essential characteristics and pregnancy outcomes including clinical pregnancy, ectopic pregnancy, abortion and live birth were analyzed. Conditional logistic regression analysis and subgroup analysis were performed.
Results
In the whole samples, atosiban had no effects in the pregnancy outcomes. Subgroup analyses suggested that atosiban could improve the clinical pregnancy in more than 3 embryo transfer cycles (OR = 1.667, 95%CI = 1.108–2.509, P = 0.014). Moreover, the improvement of clinical pregnancy was mainly present in the advanced-age women (Age ≥ 35 years: OR = 1.851, 95%CI = 1.136–3.014, P = 0.013), obesity (BMI ≥ 24 kg/m2: OR = 2.550, 95%CI = 1.105–5.883, P = 0.028) and cleavage stage embryo (D3 embryo: OR = 1.721, 95%CI = 1.098–2.696, P = 0.018) among the repeated implantation failures (RIF). Atosiban could also improve the live birth for the obese women. Further, in the RIF, atosiban application was strongly recommended for the advanced-age infertility women, who also had the risk of obesity (Clinical pregnancy: OR = 3.342, 95%CI = 1.249–8.942, P = 0.016; Live birth: OR = 12.123, 95%CI = 2.191–67.089, P = 0.004) and transferred the cleavage stage embryo (D3 embryo: OR = 1.922, 95%CI = 1.135–3.255, P = 0.015).
Conclusion
Atosiban in fresh ET cycle could improve the clinical pregnancy rate and live birth for the advanced-age and obese women undergoing more than 3 embryo transfer cycles, especially when transplanting the cleavage stage embryo.
A Framework for Generating Disparity Map from Stereo Images using Deep Learning
Authors: Karimi Hossein , Dolati Ardeshir , Layeghi Kamran 
Published: October 2022

Abstract
One of the most important functions of the human vision system is the three-dimensional perception of the surrounding environment. The image formed on the retina is actually a reflection of light patterns emitted from the real environment. The two images formed in two eyes differ from each other due to the spatial difference of the two eyes in the horizontal direction, and every point in the three-dimensional space does not appear in the same position in the image of the two retinas, which is the basis of depth perception. These results became the source of extensive research to extract depth by means of two or more images taken from the same scene and from different positions. Creating the appearance of 3D shapes based on photographs by computational techniques is of great interest in the field of machine vision research. Challenges in existing methods such as high error rate and computational costs in these fields have led to new methods in this field. Today, we can create 3D models with images of physical environments and through machine vision methods. Today, machine vision has many applications, including optical character recognition, medical imaging, surveillance, security, and many other things. In this process, the pair of stereo images taken from the real world is used by calculating the disparity of the pixels to estimate the three-dimensional space. In this paper, a framework for creating a disparity map using deep learning is presented, which is presented to solve or reduce the existing problems. Our proposed method is called SIUDL, which is presented using deep learning and based on various criteria such as RMSE errors and 3-pixel error, it has been able to have a lower error rate and better efficiency than methods such as DispNet, GA-Net and PSMNet. The simulation results show that our proposed method has reduced the error rate by 60% compared to the stated methods.
Visual inspection via a global-to-local optimization method for agarwood sticks
Authors: Yuan An , Cai Nian , Wu Zhouyixiao , Wu Zhiliang , Xu Shaoqiu , Ou Weicheng , Wan Han 
Published: October 2022

Abstract
Chemical composition analysis, chromatography and spectroscopy are dominate quality evaluation methods for agarwood, which are cumbersome and time-consuming. To facilitate its quality evaluation, a global-to-local optimization method is proposed to automatically inspect the appearance of the burned agarwood stick. First, a dissimilarity coefficient is defined by the attributes of the connected domains to coarsely localize the carbon line region. Then, the threshold for the coarsely localized carbon line region is adaptively determined based on grayscale characteristics of image patches partitioned from the coarsely localized carbon line region. Next, the threshold is used to extract the contour of the carbon line region and to establish the fine localization model for locally and precisely localizing the carbon line region. Finally, an ash shrinkage compensation coefficient is defined to calculate the ash shrinkage rate (ASR). The ASR combined with carbon line height is utilized to characterize the appearance of burned agarwood. Experimental results indicate that the proposed inspection method can well detect the carbon line regions and ashes of burned agarwood sticks, with a mean ASR error of 0.74%, which is superior to some existing inspection methods.
Double Fabry-Pérot etalons assistant injection-seeded single-frequency Tm,Ho:YLF laser
Authors: Yue Fangxin , Zhang Junxuan , Meng Jie , Yu Ting , Bi Decang , Zhu Xiaolei , Liu Jiqiao , Chen Weibiao 
Published: October 2022

Abstract
In this paper, we report a diode side-pumped injection-seeded single-frequency Tm,Ho:YLF laser, which operated at lasing threshold and emitted at 2051.2 nm. The assistance of Fabry-Pérot (FP) etalons to seed injection via mode selection was investigated. An acouto-optic Q-swiched output of 6.7 mJ was achieved at 5 Hz. A temporal pulse duration of 310 ns with spectral linewidth of 2.0 MHz and frequency stability of 0.8 MHz rms was detected. The beam profile was a high quality Guassian TEM00 mode with M2x/y = ~ 1.15/1.14. The application of this 2 µm laser as light source in the wind detection coherent Lidar system was verified.
Shear Performance of Tapered Beams with Corrugated Steel Webs with Consideration of Positive and Negative Resal Effects
Authors: Shen YongJiang , Wang Jixiang , Zhou Man , Su Xiaolong , Tanwari Kamran Anwar 
Published: October 2022

Abstract
This paper theoretically and numerically studies the difference of shear performance between tapered and uniform beams with corrugated steel webs (CSWs) and investigates the influence of Resal effect on the shear performance of tapered beams with CSWs. Free Body Cut in ABAQUS was defined to study the shear sharing proportions between CSWs and concrete slabs, it was found to be different when compared with the uniform beams with CSWs, the sloping bottom slabs in the tapered cases would involve in resisting the shear force on the section. The existence of the Resal effect in the non-uniform members may either increase or decrease the shear-bearing ratio of the CSWs. Based on its favorable and unfavorable influences on the tapered CSWs' shear properties, the concept of positive and negative Resal effects is proposed for the first time in this study, and on this basis, the improved shear method considering the positive and negative Resal effects is proposed to obtain the actual shear forces of the tapered CSWs. Additionally, the factors contributed to the positive and negative Resal effects and the mechanisms of the Resal effect on adjusting the proportion of shear forces between bottom slab and CSWs were also investigated. In this study, the Resal effects in different kinds of tapered beams with CSWs (regular tapered beam and reverse tapered beam) under different internal force combinations are discussed by using finite element (FE) models and theoretical analysis, and the correctness of the improved shear method is confirmed by contrasting the FE results.
Identification of an immune-related genes signature in lung adenocarcinoma to predict survival and response to immune checkpoint inhibitors
Authors: Davoodi-Moghaddam Zeinab , Jafari-Raddani Farideh , Kordasti Shahram , Bashash Davood 
Published: October 2022

Abstract
Background
Although advances in immune checkpoint inhibitor (ICI) research have provided a new treatment approach for lung adenocarcinoma (LUAD) patients, their survival is still unsatisfactory, and there are issues in the era of response prediction to immunotherapy. We aimed to develop a prognostic model based on immune-related genes (IRGs) to predict the overall survival (OS) as well as response to ICIs in LUAD patients.
Methods
Using bioinformatics methods, a prognostic signature was constructed and its predictive ability was validated both in the internal and external datasets (GSE68465). We also explored the tumor-infiltrating immune cells, mutation profiles, and immunophenoscore (IPS) in the low-and high-risk groups.
Results
A prognostic signature based on 9-IRGs, including BIRC5, CBLC, S100P, SHC3, ANOS1, VIPR1, LGR4, PGC, and IGKV4.1 was developed. According to multivariate analysis, the 9-IRG signature provided an independent prognostic factor for OS in LUAD patients. The low-risk group had better OS, and the tumor mutation burden (TMB) was significantly lower in this group. Moreover, the risk scores were negatively associated with the tumor-infiltrating immune cells, like CD8+ T cells, macrophages, dendritic cells, and NK cells. In addition, the IPS were significantly higher in the low-risk group as they had higher gene expression of immune checkpoints, suggesting that ICIs could be a promising treatment option for low-risk LUAD patients.
Conclusion
Our 9-IRGs prognostic signature could be useful in predicting the survival of LUAD patients and their response to ICIs; hoping this model paves the way for better stratification and management of patients in clinical practice.
Applying geomatics techniques for documenting heritage buildings in Aswan region, Egypt: A Case study of the Temple of Abu Simbel.
Authors: Elbshbeshi Abdelhamid , Gomaa Ahmed , Mohamed Abdelmonem , Othman Amal , Ghazala Hosni 
Published: October 2022

AbstractConservation and restoration of heritage sites have recently become more popular through 3-D modelling and digital documentation of heritage. The main objective of the current study is to develop a digital documentation process for Abu Simbel temple, which is one of the most famous archaeological sites in Egypt, focusing on its potential to replace obsolete methods of building heritage documentation using laser scanning. A combination of various techniques was used to produce a 3-D digital model. A precise geodetic network has been established around the temple, consisting of five points that helped in producing the 3-D model with geographic coordinates which through the rate of deformation around the temple could be calculated. Afterward, 52 scans of the temple facade and its interior parts were taken with the use of Trimble TX6 laser scanner. A 3-D digital model of the temple was obtained, encompassing geometric data, structural, architectural, and historical details as well as non-engineering data, including appearance, inscriptions, and material details. Outputs from the 3-D point cloud model exhibit a 6 mm spacing between points with a standard error of 4 mm and a standard deviation of 5 mm. In addition, a virtual tour was conducted in the temple including 61 panoramic images. Moreover, this a virtual tour would help in enhancing historical awareness, promoting tourism, and also enabling restoration work on any part that is vulnerable to deformation for any reason.