bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual Inspection of Cervix wiih Acetic Acid as A Method of Cervical Cancer Screening in Tertiary Hospital
Authors: Begum Kamrun Nesa , Shahanaz Shoyela , Rashid Fahmida , Rehena Zeenat , Chowdhury Shahanara , Sharmin Shahanaj , Baidya Chinmoy 
Published: April 2022

Background: Cervical cancer belongs to a glorious natural history which favors well implemented secondary prevention. Considering the various constraints in our country, our study aimed to evaluate Visual Inspection of Cervix with Acetic Acid (VIA) as an alternative or adjunct to cervical cytology (Pap smear) in early detection of cervical cancer and also to assess its effectiveness as a screening method in a tertiary center outside of low resource settings.
Materials and methods: This cross-sectional descriptive study was carried out at Gynae OPD of Chittagong Medical College Hospital (CMCH) from January to December 2012. A total of 1600 sexually active women with 21 to 60 years old were enrolled in this study by purposive sampling technique. The women underwent a complete clinical evaluation, including Pap smear and VIA. Any positive test was referred to colposcopy and directed biopsy. Finally, data were analyzed with the help of SPSS 16 software.
Results: Out of 1600, VIA was positive in 135(8.4%) and cytology was positive in 74(4.6%) cases of the true positive 48 cases. The sensitivity of VIA (75%) was much higher than that of Pap smear (48%). The sensitivity ratio 1.54 (p<0.001). The positive predictive value for detection of CIN2 and above was 17% for VIA and 16% for pap (p=0.5). Moreover, patients of lost to follow-up before colposcopy and biopsy were only 4.44% with VIA positive cases while 28.38% with positive Pap smear (p<0.0001).
Conclusions: The high sensitivity of VIA indicates that it may be a feasible alternative test for detection of precancerous lesions of the cervix not only in limited-resource settings but also in a well-equipped tertiary hospital.
IAHS Medical Journal Vol 4(2), June 2021; 22-26
Immediate Outcome of Mechanically Ventilated Neonate : One Year Experience in Neonatal Intensive Care Unit of Combined Military Hospital Dhaka
Authors: Das Bijoy Kumar , Fatema Begum Nurun Nahar , Yasmeen Sabina , Raha Biplob Kumar 
Published: April 2022

Background: A large number of neonates in intensive care unit require mechanical ventilation due to various disease conditions. There has been a dramatic fall in neonatal mortality in developed countries with the advent of mechanical ventilation. This study was carried out to see the immediate outcome of neonates who required mechanical ventilation.
Materials and methods: This prospective observational study was carried out in Neonatal Intensive Care Unit, CMH Dhaka from January 2016 to December 2016. Neonates who required mechanical ventilation during the study period were enrolled in this study. During the time of mechanical ventilation neonates were followed up for any complication till discharge or death.
Results: Total 30 neonates were enrolled in the study. Among them 22(73.3%) of the neonates were preterm and 8(26.7%) were term, 25(83.3%) having birth weight <2500 gm. Respiratory Distress Syndrome was the most common reason for mechanical ventilation accounting for 11(36.7%),other indications were Perinatal Asphyxia 7(23.3%), Septicemia 6(20.0%), Congenital Pneumonia 5(16.7%) and Meconium Aspiration Syndrome 1(3.3%). Common complications during the period of ventilation were Septicemia (40.0%), Acute Renal Failure (16.7%), Pneumonia (16.7%), Pulmonary Hemorrhage (10.0%), Intraventricular Hemorrhage (6.7%), Pneumothorax(10.0%) and Heart Failure (6.7%). 17(56.7%) neonates survived and 13(43.3%) were died. Most of the neonate died of Perinatal Asphyxia 4(57.1%), Septicemia 3(50.0%), RDS 5(45.5%) and Congenital Pneumonia 1(20.0%).
Conclusion: The survival rate of ventilated neonates was 56.7%. The higher gestational age and birth weight was significantly associated with better outcome. Septicemia and Pneumonia (PNA) was the leading cause of death in this study. Effective measures for prevention and management of sepsis could improve the outcome of neonates in NICU.
IAHS Medical Journal Vol 4(2), June 2021; 27-32
Os agentes desencadeantes das diversas formas de Pericardite: uma abordagem cardiológica
Authors: Carvalho Lanna do Carmo , Meneses Alyce Garcia , Vieira Inês Carvalho de Castro , Alverne Maria da Conceição Azevedo Frota Mont , Caiado Nuno Brandão Di Barros Cachapuz , Silva Sofia Carneiro Mansur , Souza Elizabeth Maria Neves Silva , Vieira José Talison , Silva Maurício Mercê da , Oliveira Pedro Henrique Santos 
Published: April 2022

Objetivo: Descrever as principais etiologias responsáveis pelo desenvolvimento das diversas apresentações da pericardite. Metodologia: Se trata de uma revisão narrativa de literatura fundamentada nas plataformas do SciELO, Google Acadêmico, LILACS, Brazilian Journal of Health Review, Research, Society and Development e Pubmed no período de janeiro a março de 2022, utilizando os seguintes descritores: pericardite, informação cardíaca e pericardiopatias. Foram achados 36 artigos nos idiomas português, inglês e espanhol, posteriormente submetidos aos critérios de análise e seleção. Foram selecionados 20 artigos por estarem na íntegra, baseados em evidências, atuais, com linguagem clara, direta e baseados em evidências, descartando se os demais que estavam duplicados, dispostos na forma de resumos e que não atendiam ao objetivo proposto. Resultados: A pericardite é um processo inflamatório do espaço membranoso que envolve o coração. Este acometimento pode assumir diferentes formas conforme o seu período, o agente etiológico e os impactos clínicos subjacentes. É existente na literatura a classificação da pericardite na forma aguda e crônica, sendo estas para mencionar os primeiros episódios e também processos extensos e evolutivos e estas possuem agentes de ordem infecciosa ou não. Os agentes infecciosos podem ser os agentes virais, bacterianos, fúngicos e parasitários e os que são manifestações de doenças sistêmicas como a de cunho autoimune, neoplasias, metabólico ou induzido por drogas. Conclusão: A pericardite é um evento patológico complexo, na maioria das vezes é benigno e sem alardes por ser de origem viral facilmente tratado, mas outros agentes necessitam de diagnósticos e condução terapêutica avançada para evitar morbimortalidade.
Uma reflexão sobre o processo de avaliação na utilização da Resolução de Problemas no ensino de Matemática
Authors: Mota Felipe Miranda , Lozada Claudia de Oliveira 
Published: April 2022

O estudo objetiva apresentar uma discussão sobre o processo de avalição durante a Resolução de Problemas. Para tal, buscamos apoio nos referenciais que tratam do que é um problema matemático, algumas concepções sobre Resolução de Problemas e o processo de avaliação no ensino e na aprendizagem. A partir de uma investigação de abordagem qualitativa com viés exploratório e descritivo, buscamos pesquisas que tratam da avaliação no ensino e na aprendizagem da Matemática através da Resolução de Problemas, o que nos remeteu à reflexão de uma avaliação que não tenha como foco o resultado por meio de testes ou avaliações, mas a observação como instrumento que permite avaliar todo o processo de aquisição do conhecimento. Além disso, a discussão nos permitiu a construção de uma rubrica avaliativa baseada em ações.
HUBUNGAN PEMBELAJARAN DARING DIMASA PANDEMI COVID-19 DENGAN MOTIVASI BELAJAR SISWA
Authors: Aminuddin Aminuddin , Rahman Abraham , Nurlansi Nurlansi 
Published: April 2022

ABSTRAKPenelitian ini bertujuan untuk mengetahui hubungan pembelajaran daring dimasa pandemi Covid-19 terhadap motivasi belajar kimia siswa SMA Kelas XI di Kota Kendari. Penelitian ini merupakan penelitian deskriftif kuantitatif dengan menggunakan metode survei. Populasi dalam penelitian ini adalah guru dan siswa kelas XI IPA SMA di Kota Kendari dengan jumlah guru sebanyak 17 orang dan siswa sebanyak 2266 orang. Pengambilan sampel menggunakan teknik purposive sampling dengan jumlah sampel siswa sebanyak 325 orang, sedangkan sampel guru adalah sejumlah populasi. Pengumpulan data menggunakan kuisioner (angket), observasi, dan wawancara terstruktur. Data dianalisis secara deskriftif dan inferensial. Hasil analisis data menunjukkan bahwa proses pembelajaran daring terlaksana cukup baik dengan kategori sedang dengan nilai rata-rata sebesar 69,61 dan nilai rata-rata motivasi belajar sebesar 71,08 tergolong kategori sedang Hasil uji korelasi sederhana menunjukkan pembelajaran daring dengan motivasi belajar mendapatkan nilai koefisien korelasi sebesar 0,148 yang tergolong sangat rendah. Dengan demikian data tersebut menunjukkan bahwa hubungan pembelajaran daring dimasa pandemi covid-19 terhadap motivasi belajar kelas XI SMA di Kota Kendari sangat rendah. Kata Kunci : Pembelajaran Daring, Motivasi Belajar.
HUBUNGAN MOTIVASI BELAJAR DAN PENGETAHUAN KONSEP IPA DALAM PEMBELAJARAN DARING PADA SISWA KELAS VIII SMPN DI KOTA KENDARI
Authors: Sumaili La Ode , Jahidin Jahidin , Jamili Jamili 
Published: April 2022

Abstrak. Tujuan penelitian ini adalah untuk menganalisis hubungan antara motivasi belajar dan pengetahuan konsep IPA dalam pembelajaran daring pada peserta didik SMPN Kelas VIII di Kota Kendari. Penelitian ini merupakan penelitian survey dengan pendekatan mixed method. Populasi dalam penelitian ini adalah sebanyak 4274 peserta didik SMPN kelas VIII di Kota Kendari. Teknik pengambilan sampel pada penelitian ini dilakukan dengan teknik proportional random sampling yaitu semua anggota mempunyai kesempatan yang sama untuk dijadikan sampel sesuai dengan proporsinya. Besarnya jumlah sampel ditentukan dengan menggunakan rumus slovin sehingga jumlah sampel penelitian 366 orang. Data penelitian diperoleh melalui kuesioner penelitian yang dibuat di google form berupa angket motivasi belajar dan tes pengetahuan konsep. Hasil penelitian menunjukkan bahwa: 1) tingkat motivasi belajar selama pembelajaran daring pada peserta didik berada pada tingkat tinggi yang ditunjukkan dengan nilai rata-rata motivasi belajar sebesar 79,93; 2) tingkat pengetahuan konsep IPA selama pembelajaran daring pada peserta didik berada pada tingkat rendah yang ditunjukkan dengan nilai rata-rata pengetahuan konsep sebesar 46,55; 3) tidak ada hubungan antara motivasi belajar dan pengatahuan konsep dalam pembelajaran daring pada peserta didik yang dibuktikan dengan nilai signifikansi sebesar 0.384 > α = 0,05. Artinya bahwa motivasi belajar bukan penentu meningkatnya pengetahuan konsep peserta didik selama pembelajaran daring. Kata Kunci: pembelajaran dalam jaringan, motivasi belajar, pengetahuan konsep
ANALISIS PENGUASAAN KONSEP DAN MISKONSEPSI SISWA PADA MATERI SEL KELAS XI MIPA MELALUI METODE CRI (CERTAINTY RESPONS INDEX) DI SMAN 1 WAWOTOBI KABUPATEN KONAWE
Authors: Dinarni Dinarni , Safilu Safilu , Wirdhana Sitti 
Published: April 2022

Abstrak. Tujuan penelitian ini adalah untuk menganalisis penguasaan konsep dan miskonsepsi siswa pada materi sel kelas XI MIPA melalui metode Certainty Of Response Index (CRI) pada materi sel pada di SMA Negeri 1 Wawotobi. Populasi dalam penelitian ini adalah siswa kelas XI MIPA di SMAN 1 Wawotobi Kabupaten Konawe. Teknik pengambilan sampel pada penelitian ini adalah teknik purposive sampling yang terdiri dari 3 kelas dengan jumlah siswa 103. Jenis penelitian ini menggunakan metode analisis deskriptif.Hasil analisis data menunjukkan bahwa: 1) Penguasaan konsep siswa pada materi sel di kelas XI MIPA SMAN 1 Wawotobi Kabupaten konawe secara umum lebih tinggi dibandingkan dengan siswa yang mengalami miskonsepsi. 2) Berdasarkan nilai persentase indikator penguasaan konsep tertinggi ditemukan pada indikator mengidentifikasi pada soal nomor 4 sebesar 79,4%, sedangkan penguasaan konsep terendah ditemukan pada indikator mengindentikasi dan menjelaskan pada soal nomor 17 dan 20 sebesar 0%. Siswa yang mengalami miskonsepsi tertinggi ditemukan pada indikator mengidentifikasi pada soal nomor 14 sebesar 73,6% sedangkan miskonsepsi terendah ditemukan pada indikator mengindentikasi dan menjelaskan pada soal nomor 14, 16, 18 dan 15 sebesar 2,8% dan 5,6%. Kata Kunci: analisis penguasaan konsep, miskonsepsi siswa
ANALISIS KEMAMPUAN PEMECAHAN MASALAH DI TINJAU DARI ADVERSITY QUOTIENT (AQ) MELALUI MODEL PEMBELAJARAN BERBASIS MASALAH
Authors: Samandy Vebryatin , Anas Muhammad , Zamrun Muhammad 
Published: April 2022

Abstrak. Tujuan penelitian ini adalah untuk mengetahui pengaruh model pembelajaran Berbasis Masalah dan Adversity Qoutient (AQ) terhadap kemampuan pemecahan masalah. Penelitian ini merupakan quasi experimental dan desain penelitian menggunakan pretest-posttest control group design yang dimodifikasi dengan faktorial 2 x 2. Sampel penelitian ini adalah siswa SMA N 1 Kontukowuna keseluruhan populasi yaitu, kelas XI MIA1 dengan 24 peserta didik belajar melalui model PBM dan kelas XI MIA2 dengan 24 peserta didik belajar melalui pembelajaran konvensional. Data penelitian diperoleh melalui (1) Tes KPM dalam bentuk soal essay dan (2) angket AQ. Hasil analisis data memberikan kesimpulan 1) bahwa kemampuan pemecahan masalah siswa yang menggunakan model pembelajaran berbasis masalah lebih baik dari pembelajaran konvensional, 2) kemampuan pemecahan masalah siswa yang memiliki rata – rata adversity quotient tinggi lebih baik daripada siswa yang memiliki rata-rata adversity quotient rendah, 3) Terdapat interaksi antara model pembelajaran berbasis masalah dan pembelajaran konvensional dengan adversity quotient untuk meningkatkan kemampuan Pemecahkan masalah. Kata Kunci: model pembelajaran berbasis masalah, adversity quotient, kemampuan pemecahan masalah
KEBERLANJUTAN WISATA BAHARI PULAU HOGA DENGAN PENDENKATAN WILAYAH
Authors: Tahir Mustaman , La Rianda Rianda , Natsir Muhammad 
Published: April 2022

Tujuan penelitian ini yaitu mengetahui pola pemanfaatan lahan Pulau Hoga dalam menunjang kegiatan wisata bahari, dan upaya yang dilakukan untuk keberlanjutan wisata bahari di Pulau Hoga. Metode yang digunakan yaitu analisis spasial dan analisis deskriptif. Hasil penelitian menyatakan bahwa pemanfaatan lahan Pulau Hoga yang menunjang kegiatan wisata dilakukan dengan menambah atraksi wisata seperti olahraga selancar, meningkatkan sarana transportasi, pengadaan fasilitas pendukung kegiatan wisata bahari sehingga dapat memberikan kenyamanan bagi wisatawan, menciptakan tenaga profesional dengan cara pengembangan sumber daya manusia untuk meningkatkan promosi kepariwisataan.
OPTIMALISASI TATA LETAK BANGUNAN UNTUK PEMANFAATAN RUANG KAMPUS BARU UNIVERSITAS HALU OLEO (UHO)
Authors: Hasan La Ode Amrul , Rianse Usman , Hemon Tufaila 
Published: April 2022

Kampus Baru Universitas Halu Oleo (UHO) merupakan salah satu perguruan tinggi negeri yang termasuk dalam kandidat kampus terluas se-Indonesia Timur dengan luas areal lebih dari 252 Ha. Berada di kawasan pengembangan pusat pemerintahan membuat Kampus baru UHO menjadi kampus yang terfavorit hal ini ditunjukan dengan bertambahnya jumlah calon mahasiswa dari tahun ke tahun. Bertambahnya jumlah mahasiswa mendorong penyediaan fasilitas pendidikan sebagai kebutuhan utama. Keberadaan bangunan yang ada saat ini dan rencana-rencana pembangunan kedepan belum mempertimbangkan konsep penataan ruang yang baik sehingga bangunan yang ada tumbuh dan berkembang mengikuti ketersediaan lahan saja sehingga cenderung tumbuh tanpa arahan yang jelas, hal ini mengancam ketersediaan lahan khususnya ketersediaan ruang terbuka dan berdampak pula pada penataan elemen yang terkait seperti sirkulasi kendaraan, utilitas bangunan, sistem drainase dan mekanikal elektrikal.nTujuan dari penelitian ini adalah untuk memberikan rekomendasi desain tata ruang kampus UHO yang mengoptimalkan ketersediaan ruang terbuka 60% secara proporsional dengan konsep penataan yang lebih terarah.mHasil penelitian ini menunjukkan bahwa kondisi penataan bangunan yang ada saat ini yang tidak tertat dengan baik sehingga berpengaruh pada elemen lainnya. Melalui arahan konsep cluster eco kampus kawasan kampus akan lebih tertata. Kata kunci : Tata letak bangunan, clusterecocampus, UHO
STUDI FENOMENOLOGI : KOPING STRATEGI ORANG TUA YANG MENGALAMI HIV/AIDS
Authors: LUSIANI ELI 
Published: April 2022

Data pasien yang terinfeksi HIV terus meningkat pesat dan tersebar luas di seluruh Dunia. Individu yang dinyatakan terinfeksi HIV, sebagian menunjukkan perubahan baik secara biopsikososio dan spritual yang berdampak pada dirinya dan orang di sekitar, sehingga memerlukan suatu strategi koping. Strategi koping merupakan cara individu menyelesaikan masalah. Tujuan penelitian ini adalah untuk mengetahui strategi koping pasien HIV/AIDS. Desain penelitian menggunakan desain kualitatif dengan pendekatan Empirical Phenomenological Psychological (EPP),dilakukan secara purposive sampling methods terhadap 4 responden. Hasil penelitian di dapatkan 5 tema yaitu : Strategi koping berorientasi pada situasi, Strategi koping berorientasi pada emosi, Strategi koping berorientasi pada pencegahan, Strategi koping berorientasi pada agama, Strategi koping berorientasi pada eksistensi. Penelitian ini mengindikasikan perlunya memberikan dukungan dan mendorong pasien HIV/AIDS dalam menemukan atau meningkatkan koping individu yang adaptif, dan memfasilitasi pasien HIV/AIDS mendapatkan sumber-sumber dukungan. Sehingga pasien HIV/AIDS dapat beradaptasi terhadap kondisinya dan mampu mengelola penyakit yang dialaminya.
The Role of Syncytin in Placental Angiogenesis and Fetal Growth
Authors: Wang Ya-Nan , Ye Yixin , Zhou Da , Guo Ze-Wen , Xiong Zhelei , Gong Xing-Xing , Jiang Shi-Wen , Chen Haibin 
Published: April 2022

Background: Syncytin, a retroviral envelope protein, is specifically expressed on trophoblast cells and mediates formation of the syncytiotrophoblast through fusogenic activity. Decreased expression of Syncytin was found in fetal growth restriction placentas.Results: By generating an inducible knockout of the syncytin-a gene in mice, we show a specific disruption of placental angiogenesis with abnormal formation of two syncytiotrophoblast layers. Consistent with the defects observed in vivo, conditioned medium collected from trophoblast cells, following Syncytin-1 knockdown, contains lower expression of vascular endothelial growth factor and placental growth factor, and higher levels of soluble fms-like protein kinase-1 in BeWo and HTR-8/SVneo cells which related with suppressed PI3K/Akt/mTOR pathway, and is reduced in ability to induce tube formation by HUVECs.Conclusion: Syncytin participates in angiogenesis during placental development was first identified both in vivo and in vitro. Here, we give a new sight on understanding syncytin and pathophysiology of placenta related disease such as fetal growth restriction.
Relationship Between Resting Heart Rate and Microalbuminuria in Adults With Hypertension: National Health and Nutrition Examination Survey 2009–2018
Authors: Peng Xiaodong , Li Yukun , Wang Xuesi , Ruan Yanfei , Liu Nian 
Published: April 2022

BackgroundThe impact of elevated resting heart rate on early-stage renal dysfunction, manifesting as microalbuminuria, in hypertension is unclear. This study aimed to analyze the association between resting heart rate and microalbuminuria in patients with hypertension according to their blood pressure status. In addition, the effect of antihypertensive agents on this relationship was evaluated.Methods and ResultsWe searched the National Health and Nutrition Examination Survey for eligible participants from 2009 to 2018. Data on key parameters such as age, sex, blood pressure, heart rate, albumin creatinine ratio, and medication were collected for analysis. Subsequently, participants were classified according to the heart rate quartile and blood pressure status for subgroups assessment. A total of 5,692 participants were enrolled in this study. After adjusting the confounding factors, there was a linear association between resting heart rate and microalbuminuria in patients with hypertension (OR 1.184 [per 1 SD]; 95% CI: 1.101, 1.274; P &lt; 0.001). However, the association between elevated resting heart rate and microalbuminuria was not significant in patients with uncontrolled hypertension (OR 1.092 [per 1 SD]; 95% CI: 0.935, 1.275; P = 0.269). The OR of the indirect effect of β-blockers on the risk of microalbuminuria incidence through heart rate was 0.926 (95% CI: 0.895, 0.956), while the direct effect was 1.374 (95% CI: 1.138, 1.662, P = 0.010). Similarly, dihydropyridine calcium channel blockers were associated with a higher prevalence of microalbuminuria (OR 1.300, 95% CI: 1.058, 1.597, P = 0.013), but the association between non-dihydropyridine calcium channel blockers and microalbuminuria was not significant (OR 1.207, 95% CI: 0.737, 1.978, P = 0.454).ConclusionElevated resting heart rate is associated with a high risk of microalbuminuria in untreated patients and patients with controlled hypertension. Although there is a linear association between heart rate and microalbuminuria, the use of β-blockers exhibits a significantly increase in the prevalence of microalbuminuria in hypertension. Likewise, dihydropyridine calcium channel blockers may increase the risk of microalbuminuria in hypertension.
Outcomes With Multidisciplinary Cardiac Rehabilitation in Post-acute Systolic Heart Failure Patients—A Retrospective Propensity Score-Matched Study
Authors: Chen Shyh-Ming , Wang Lin-Yi , Liaw Mei-Yun , Wu Ming-Kung , Wu Po-Jui , Wei Chin-Ling , Chen An-Ni , Su Tsui-Ling , Chang Jui-Kun , Yang Tsung-Hsun , Chen Ching , Cheng Cheng-I , Chen Po-Cheng , Chen Yung-Lung 
Published: April 2022

BackgroundCardiac rehabilitation (CR) is recommended for patients with acute heart failure (HF). However, the results of outcome studies and meta-analyses on CR in post-acute care are varied. We aimed to assess the medium- to long-term impact of CR and ascertain the predictors of successful CR.MethodsIn this propensity score-matched retrospective cohort study, records of consecutive patients who survived acute HF (left ventricular ejection fraction &lt;40) and participated in a multidisciplinary HF rehabilitation program post-discharge between May 2014 and July 2019 were reviewed. Patients in the CR group had at least one exercise session within 3 months of discharge; the others were in the non-CR group. After propensity score matching, the primary (all-cause mortality) and secondary (HF readmission and life quality assessment) outcomes were analyzed.ResultsAmong 792 patients, 142 attended at least one session of phase II CR. After propensity score matching for covariates related to HF prognosis, 518 patients were included in the study (CR group, 137 patients). The all-cause mortality rate was 24.9% and the HF rehospitalization rate was 34.6% in the median 3.04-year follow-up. Cox proportional hazard analysis revealed that the CR group had a significant reduction in all-cause mortality compared to the non-CR group (hazard ratio [HR]: 0.490, 95% confidence interval [CI]: 0.308–0.778). A lower risk of the primary outcome with CR was observed in patients on renin-angiotensin-aldosterone system (RAAS) inhibitors, but was not seen in patients who were not prescribed this class of medications (interaction p = 0.014).ConclusionsCardiac rehabilitation participation was associated with reduced all-cause mortality after acute systolic heart failure hospital discharge. Our finding that the benefit of CR was decreased in patients not prescribed RAAS inhibitors warrants further evaluation.