bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low frequency cerebral arterial and venous flow oscillations in healthy neonates measured by NeoDoppler
Authors: Ødegård Siv Steinsmo , Torp Hans , Follestad Turid , Leth-Olsen Martin , Støen Ragnhild , Nyrnes Siri Ann 
Published: November 2022

BackgroundA cerebroprotective effect of low frequency oscillations (LFO) in cerebral blood flow (CBF) has been suggested in adults, but its significance in neonates is not known. This observational study evaluates normal arterial and venous cerebral blood flow in healthy neonates using NeoDoppler, a novel Doppler ultrasound system which can measure cerebral hemodynamics continuously.MethodUltrasound Doppler data was collected for 2 h on the first and second day of life in 36 healthy term born neonates. LFO (0.04–0.15 Hz) were extracted from the velocity curve by a bandpass filter. An angle independent LFO index was calculated as the coefficient of variation of the filtered curve. Separate analyses were done for arterial and venous signals, and results were related to postnatal age and behavioral state (asleep or awake).ResultsThe paper describes normal physiologic variations of arterial and venous cerebral hemodynamics. Mean (SD) arterial and venous LFO indices (%) were 6.52 (2.55) and 3.91 (2.54) on day one, and 5.60 (1.86) and 3.32 (2.03) on day two. After adjusting for possible confounding factors, the arterial LFO index was estimated to decrease by 0.92 percent points per postnatal day (p &lt; 0.001). The venous LFO index did not change significantly with postnatal age (p = 0.539). Arterial and venous LFO were not notably influenced by behavioral state.ConclusionThe results indicate that arterial LFO decrease during the first 2 days of life in healthy neonates. This decrease most likely represents normal physiological changes related to the transitional period. A similar decrease for venous LFO was not found.
Quantitative effects of sodium–glucose cotransporter-2 inhibitors dapagliflozin and empagliflozin on quality of life in heart failure patients
Authors: Wang Dong-Dong , Zhang Cun , Zhu Ping , He Su-Mei , Chen Xiao 
Published: November 2022

The aim of the present study is to investigate the quantitative effects of sodium–glucose cotransporter-2 (SGLT-2) inhibitors on the quality of life in heart failure (HF) patients. A total of 14,674 HF patients from two dapagliflozin and three empagliflozin studies is included for analysis via the nonlinear mixed-effect modeling (NONMEM) software, among which the change rate of the Kansas City Cardiomyopathy Questionnaire (KCCQ) score is used as the evaluation index. There is no significant difference in the pharmacodynamics influencing the quality of life in HF patients between the SGLT-2 inhibitors: 10 mg/day dapagliflozin and 10 mg/day empagliflozin. For the clinical summary score (CSS), total symptom score (TSS), and overall summary score (OSS), the Emax of the SGLT-2 inhibitors on the quality of life in HF patients is 3.74%, 4.43%, and 4.84%, respectively, and ET50 is 2.23, 4.37, and 7.15 weeks, respectively. In addition, the time duration of achieving 25%, 50%, 75%, and 80% Emax is 0.75, 2.23, 6.69, and 8.92 weeks for the CSS; 1.46, 4.37, 13.11, and 17.48 weeks for the TSS; and 2.39, 7.15, 21.45, and 28.6 weeks for the OSS, respectively. Therefore, to reach the plateau period (80% of Emax) of SGLT-2 inhibitors on the CSS, TSS, and OSS, 10 mg/day dapagliflozin (or 10 mg/day empagliflozin) is required to be taken for 8.92 weeks, 17.48 weeks, and 28.6 weeks, respectively. This is the first time that the quantitative effects of SGLT-2 inhibitors on the quality of life in HF patients are being explored.
Relationships between job satisfaction, organizational commitment, burnout and job performance of healthcare professionals in a district-level health care system of Shenzhen, China
Authors: Wang Xin , Li Chaofan , Chen Yuanqing , Zheng Caiyun , Zhang Fei , Huang Yixiang , Birch Stephen 
Published: November 2022

BackgroundExisting research indicates that job satisfaction has effects on job performance, but little evidence exists about the mechanism through which the satisfaction-performance association operates. This study aims to examine the effect of job satisfaction on job performance in a district-level health care system of China and to explore the effect mechanism mediated by organizational commitment and burnout.MethodsCluster sampling was used in this study. All healthcare professionals in the Nanshan Medical Group, who were at work in the last 3 months and able to complete online questionnaire independently were invited to participate the anonymous online survey. Job satisfaction, organizational commitment, burnout and job performance were measured by tools, which have been validated in China. Descriptive statistics were used for the socio-demographic variables and the four job psychological variables. Pearson correlation coefficients was used to determine associations among each of the psychological variables. Linear regression was used to examine association between job performance and other three psychological variables. PROCESS macro was used to examine the mediation effects of organizational commitment and burnout on the association between job satisfaction and performance.ResultsIn total, 1,200 healthcare professionals completed the anonymous online survey. Job satisfaction, organizational commitment, and job performance were positively correlated with one another, with burnout negatively correlated with them. Linear regression revealed that demographic characteristics, job satisfaction, organizational commitment, and burnout explained 5, 6, 2, and 9% of the variance in job performance. Path analysis showed that the coefficient of the direct effect of job satisfaction on job performance was 0.18, the coefficients of the indirect effects of job satisfaction on job performance through organizational commitment and burnout were 0.17 and 0.37, respectively. The coefficients of the indirect effects of organizational commitment on job performance through burnout was −0.04, but it was not significant.ConclusionIt is promising to improve job performance of providers in Chinese healthcare systems by improving job satisfaction and reducing burnout. Tailored support policies for female healthcare professionals, appropriate incentive mechanisms and improving multidisciplinary healthcare delivery are potential to improve job performance of healthcare professionals in integrated healthcare systems.
Depression moderates the association between pregnancy and suicidal ideation among pregnant and non-pregnant reproductive age women in Brazil
Authors: Faisal-Cury Alexandre , Tabb Karen M. , Maruyama Jessica Mayumi , Matijasevich Alicia 
Published: November 2022

BackgroundMaternal mental health problems are a serious public health concern. Previous data reported that pregnancy might have a protective effect against suicide. In contrast, more recent studies suggested that the prevalence of suicidal ideation (SI) is higher among pregnant women compared to the general population. Using a nationally representative population-based sample of Brazilian reproductive-aged women, this study aims to assess whether SI is more prevalent among pregnant women in comparison with nonpregnant woman.MethodsWe used data from the Brazilian National Health Survey (PNS) of 2019, a cross-sectional study that comprised a representative sample of residents in private households in Brazil. For the analysis of this study, we selected women aged between 15 and 49 years old who have answered the questionnaire of the Selected Resident of the PNS, which comprised a sample of 27,249 women. Logistic regression models were performed to obtain crude and adjusted odds ratios (OR) and 95% confidence intervals (95%CI) for the association between pregnancy status and SI.ResultsThe prevalence of SI during pregnancy was 6.8% (95% CI: 6.2–7.4). The association between pregnancy status and SI was modified according to the recent clinical diagnosis of depression (interaction term: OR = 41.72, 95% CI: 5.64–308.45, p &lt; 0.001). Our findings indicated that among nondepressed women, pregnancy status seems to decrease the probability of SI. Additionally, SI is associated with a vulnerable profile that includes being an adolescent, having an unpartnered/not married status, lower family income, lower education, and a recent clinical diagnosis of depression.ConclusionSI is a common problem for reproductive-age women. In the presence of a recent depression clinical diagnosis, pregnancy increases the risk of SI. Management of SI among pregnant women should correctly identify sociodemographic risk factors and the presence of a recent clinical diagnosis of depression.
Strategies to strengthen non-governmental organizations' participation in the Iranian health system
Authors: Sanadgol Arman , Doshmangir Leila , Majdzadeh Reza , Gordeev Vladimir Sergeevich 
Published: November 2022

BackgroundNon-governmental organizations (NGOs) added a new dimension to intersectoral action for health. Involving the NGOs in health system strengthening could lead to a more efficient, equitable, and better-governed healthcare system. This qualitative study explored effective strategies for NGO participation in the Iranian health system to achieve broader health system goals.MethodWe conducted 33 semi-structured interviews with health policymakers and planners, NGO actors at the national and provincial levels, and other key informants. The qualitative data were analyzed through a thematic analysis approach. Trustworthiness in the study was observed at all stages of the study.ResultFour main themes- were identified: empowerment for learning leadership and management skills, creating active participation in policy-making, capacity building for participation, clarifying participation process, falling into 17 sub-themes. Along with the government and health sector policymakers, NGOs may have a significant role in improving health system goals and increasing equity, social responsiveness, financial risk protection, and efficiency.ConclusionThe participation of NGOs in the Iranian health system is a complex process. All elements and dimensions of this process need to be considered when developing a platform for the appropriate participation of NGOs in the health system functions. Evidence-informed strategies for strengthening the participation of NGOs in the health system should be used to utilize NGOs potential to the fullest.
Forearm bone mineral density as a predictor of reduction loss in distal radius fractures treated with cast immobilization
Authors: Cho Sung Tan , Kim Jin Hwan , Lee Sung San , Lee Yong Jae , Lee Hyun Il 
Published: November 2022

ObjectiveMany potential predictors have been identified and proposed for predicting late reduction loss in distal radius fractures. However, no report exists on whether the bone mineral density (BMD) of the forearm correlates with the loss of reduction in distal radius fractures. This study aimed to investigate whether forearm BMD can be used as a predictor of reduction loss in distal radius fractures treated with cast immobilization.MethodsNinety patients with distal radius fractures were divided into two groups according to the maintenance or loss of reduction evaluated from radiographs taken at least 6 weeks after their injury. Lumbar and forearm BMD (total and metaphysis) T-scores were measured and compared between the maintenance of reduction (MOR) group and the loss of reduction (LOR) group. Additionally, serologic markers (C-terminal telopeptide, osteocalcin, vitamin D) and radiologic risk factors (intra-articular fracture, ulnar fracture, dorsal comminuted fracture, volar hook) were evaluated and a logistic multiple regression analysis was performed to know the main risk factors of reduction loss.ResultsReduction loss was observed in 38 patients (42.2%). The total and metaphyseal BMD of the forearm was less in the LOR group than in the MOR group. However, the difference was not statistically significant [−2.9 vs. −2.5 for total (p = 0.18), −2.3 vs. −2.0 for metaphysis (p = 0.17)]. Multiple logistic regression analysis showed initial dorsal comminution (p = 0.008) and ulnar variance (p = 0.01) were the main risk factors for reduction loss.ConclusionsForearm BMD was not a valuable prognostic factor for reduction loss in distal radius fractures. Initial dorsal comminution and ulnar variance rather than forearm BMD should be considered preferentially when predicting which patients are at high risk of reduction loss in distal radius fractures.
Integrasi E-procurement Pada Aplikasi SAP Krakatau Bandar Samudera Mengunakan Service Oriented Architecture
Authors: Megayanti Anita , Hendriyati Penny 
Published: November 2022

Eprocurement adalah sistem procurement berbasis web yang merupakan bagian dari sistem logistik dimulai dari e-registrasi vendor, Pengelolaan purchase requistion hingga proses draft purchase order. E-procurement ini berjalan dibawah sistem logistik, dimana sistem logistik berada pada aplikasi SAP karakatau Bandara samudera. Melihat hal tersebut maka dibutuhkan pengintegrasian antara sistem eprocurement dengan aplikasi SAP agar saling berkomunikasi dalam pertukaran data. Dalam proses integrasi eprocurement dan aplikasi SAP maka peneliti menggunakan metode service oriented architecture (SOA) yang bertujuan untuk mengotomasikan proses bisnis yang berhubungan dengan procurement / pengadaan. Metode SOA merupakan salah satu cara perancangan aplikasi dengan mengunakan komponen sistem yang ada dilakukan dengan cara permasalahan terbagi menjadi beberapa service serta berfungsi mengintegrasikan sistem yang berbeda tetapi lebih mudah beradaptasi dengan perubahan environment, selain itu juga lebih efektif dan efesien. SOA ini diterapkan karena eprocurement berbasis web sedangkan aplikasi SAP berbasis desktop sehingga memudahkan dalam pertukaran data yang memiliki perbedaan platform.
The Effectiveness of Using a Digital Method for Diagnosing Occlusion of Teeth and Magnetophototherapy in Orthopedic Treatment of Patients with Partial Secondary Adentia and Periodontal Diseases
Authors: Рубникович С.П. , Майзет А.И. 
Published: November 2022

В публикации приведены данные, доказывающие высокую эффективность нового специального комплекса лечебно-диагностических мероприятий, основанного на применении цифрового метода диагностики окклюзии с включением магнитофототерапии. Цель. Улучшить результаты ортопедического лечения пациентов с частичной вторичной адентией и хроническим периодонтитом с комплексным использованием разработанного цифрового метода диагностики окклюзии зубов и сочетанного применения низкоинтенсивного импульсного магнитного поля с поляризованным светом. Результаты. Разработанный комплекс лечебно-диагностических мероприятий, основанный на методе цифрового анализа окклюзии с использованием аппарата T-sсan и цифровых индексных показателей с включением магнитофототерапии, позволяет получить положительные результаты лечения у 94,1% пациентов, тогда как удельный вес пациентов с положительными результатами при традиционном методе лечения составляет 12,5%.
The publication presents data of proves of high efficiency of a new special complex of therapeutic and diagnostic measures based on the use of a digital method for diagnosing occlusion with the inclusion of magnetic phototherapy. Purpose. The aim of the study is to improve the results of orthopedic treatment of patients with partial secondary edentulous and periodontal diseases, using a digital method for diagnosing occlusion of teeth and magnetic phototherapy. Results. The developed complex of medical and diagnostic measures based on the digital analysis method of occlusion using the T-scan device and digital index indicators with the inclusion of magnetic phototherapy, allows to obtain positive treatment results in 94.1% of patients, while the proportion of patients with positive results in the traditional method treatment is 12.5%.
Clinical Efficiency of the Use of Means Based on Chlorhexidine in Complex Therapy of Chronic Generalized Periodontitis
Authors: Бобкова И.Л. , Зиновенко О.Г. , Кравчук И.В. , Коваленко И.П. 
Published: November 2022

Основным фактором, вызывающим развитие заболеваний периодонта, является периодонтопатогенная микрофлора полости рта. Микроорганизмы в составе биопленки способны изменять свою чувствительность к антибактериальным лекарственным средствам, при этом сохраняя чувствительность к антисептикам. В статье публикуются данные о клинической эффективности применения зубной пасты с содержанием хлоргексидина 0,2% в комплексной терапии хронического генерализованного периодонтита.
The main factor causing the development of periodontal diseases is the periodontopathogenic microflora of the oral cavity. Microorganisms in the composition of the biofilm are able to change their sensitivity to antibacterial drugs, while maintaining sensitivity to antiseptics. The article publishes data on the clinical efficacy of toothpaste containing 0.2% chlorhexidine in the complex therapy of chronic generalized periodontitis.
Risk Factors for Dental Pathology in Children with Rheumatoid Arthritis
Authors: Кадырова Е.С. , Шаковец Н.В. 
Published: November 2022

Статья посвящена актуальной проблеме детской ревматологии и стоматологии – клиническим проявлениям ювенильного идиопатического (ревматоидного) артрита в ротовой полости. Ювенильный идиопатический артрит является наиболее распространенной патологией среди воспалительных ревматических заболеваний детского возраста, кроме того, в настоящее время во всем мире наблюдается тенденция к неуклонному росту распространенности ревматических болезней как в общей, так и в детской популяции. Используя данные литературных источников, авторы систематизировали информацию об особенностях гигиены ротовой полости, состояния твердых тканей зубов, об изменениях функциональных свойств ротовой жидкости и параметров местного иммунитета у детей с ювенильным ревматоидным артритом в анамнезе. Понимание закономерностей в изменении стоматологического статуса на фоне данной патологии поможет стоматологу эффективно проводить мероприятия первичной и вторичной медицинской профилактики для этой категории пациентов.
This review deals with the actual problem of pediatric rheumatology and dentistry – clinical manifestations of juvenile idiopathic arthritis. Juvenile idiopathic arthritis is the most common pathology among inflammatory rheumatic diseases of childhood, in addition, at present there is a tendency worldwide to a steady increase in the prevalence of rheumatic diseases in both the general and children’s populations. Using data from literary sources, the authors systematized information about the properties of oral hygiene, the state of hard dental tissues, changes in the functional properties of oral fluid and parameters of local immunity in children with juvenile idiopathic arthritis in the anamnesis. Understanding the patterns in the change of dental status against the background of this pathology will help the dentist to effectively carry out primary and secondary prevention measures for this category of patients.
IMPLEMENTASI KEBIJAKAN PERATURAN DAERAH KABUPATEN PARIGI MOUTONG NOMOR 12 TAHUN 2012 TENTANG PENYELENGGARAAN PENANGGULANGAN BENCANA DI KABUPATEN PARIGI MOUTONG
Authors: Nur Fakhruddin , Mahendra Gerry Katon 
Published: November 2022

Implementasi kebijakan peraturan daerah Kabupaten Parigi Moutong nomor 12 tahun 2012 tentang penyelenggaraan penanggulangan bencana di kabupaten parigi moutong, tujuan dari penelitian ini yaitu untuk menganalisis implementasi kebijakan dan memberikan alternatif solusi atau policy brief dan atau rancangan kebijakan penanggulangan bencana di Kabupaten Parigi Moutong, dimasa depan, mengetahui adanya lintas sektor dalam penanggulangan bencana di Kabupaten Parigi Moutong, dan mengetahui faktor yang mempengaruhi keberhasilan dan kegagalan implementasi, dan juga pada tahap kesiapsiagaan dalam penaggulangan bencana. serta mengetahui bagaimana, implementasi kebijakan penanggulangan bencana pada tahap tanggap darurat bencana banjir, longsor, angin topan, ataupun abrasi di Kabupaten Parigi Moutong. Adapun penelitian ini menggunakan Metode penelitian kualitatif atau Metode naturalistik menurut Sugiyono (2016) adalah metode penelitian yang digunakan untuk meneliti pada kondisi obyek alamiah. Hasil dari penelitian ini secara umum implementasi kebijakan Peraturan Daerah Kabupaten Parigi Moutong Nomor 12 Tahun 2012 Tentang Penyelenggaraan Penanggulangan Bencana Di Kabupaten Parigi Moutong Provinsi Sulawesi Tengah sudah cukup baik, namun masih perlu perbaikan pada beberapa faktor yakni: Implemetasi kebijakan, karakteristik agen pelaksana, komunikasi antar implementor, evaluasi dan sosialisasi implementasi, sumber daya implementasi, dan lingkungan sosial. Dan hasil penelitian lapangan menunjukan masih ada sebagian kebijakan yang belum tepat pada sasarannya dan belum terselesaikan sehingga masih memicu adanya kesalahpahaman antar dua belahpihak yaitu masyarakat terdampak dan juga implementor daerah terutama kepala daerah, sehingga perlu adanya evaluasi, edukasi pencegahan terkait bencana, penanganan tanggap darurat, rehabilitas, dan rekontruksi secara andil juga merata kepada setiap daerah di Kabupaten Parigi Moutong.
PENYULUHAN DAN PENDAMPINGAN PEMBUATAN PRODUK OLAHAN PISANG SEBAGAI NILAI JUAL DAN TAMBAHAN PENDAPATAN
Authors: Lidya Natalia Sartono  , Sepni Yanti  , Maria Cleopatra  , Sarah Sahrazad  
Published: November 2022

Pembangunan ekonomi yang tangguh adalah pembangunan ekonomi yang berbasis potensi lokal, masyarakat menyadari potensi yang dimilikinya dan mereka dapat mengembangkan potensi tersebut. Para pemuda diharapkan mendapat pembekalan pengenalan dan kesadara potensi lokal tersebut. Dengan kesadaran tinggi dan mau merubah keadaan dengan kkerja keras dan ihtiar yang sunguh – sungguh, niscaya akan membuka peluang yang menjanjikan. Penyuluhan pengabdian kepada masyarakat dilakukan di Yayasan Arrahman Tangerang Jawa Barat. Jumlah peserta sebanyak 26 peserta. Metode yang digunakan adalah metode ceramah, praktik, dan diskusi. Metode ceramah digunakan untuk menjelaskan materi tentang pengolahan pisang kepok menjadi pisang goreng . Metode praktik digunakan untuk praktik membuat olahan produk pisang, mulai dari pemilihan pisang sampai dengan pengolahan . Hasil kegiatan siswa sudah dapat memproduksi dan menjual produk olahan pisang ,menjadi pisang goreng dari berbagai rasa, seperti rasa, keju,coklat, strawberry dan lain – lain. Peserta dapat mengenal nilai – nilai kemandirian serta kewirausahaan.