bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marital Loss and Cognitive Function: Does Timing Matter?
Authors: Zhang Zhenmei , Liu Hui , Zhang Yan 
Published: April 2022

Abstract

Objectives
This study examines the association between age at marital loss (i.e., divorce or widowhood) and cognitive function in later life and whether the association differs by gender.

Methods
We used mixed-effects models, drawing on longitudinal data from the Health and Retirement Study (1998–2016). The analytical samples included adults aged 51 and older who had ever been widowed (N = 5,639 with 25,537 person-waves) or divorced (N = 10,685 with 50,689 person-waves).

Results
We find that those who were widowed at younger ages had lower cognitive function than their counterparts who were widowed at older ages, for both men and women, after controlling for covariates. Household income and health-related factors partially accounted for the positive association between age at widowhood and cognitive function. Those who divorced at younger ages also had lower cognitive function than their counterparts who divorced at older ages, but this association was only present among men, not women. Health-related factors partially accounted for the association between age at divorce and cognitive function among men.

Discussion
Findings highlight the importance of considering the role of timing of marital loss in cognitive health among older adults.
Understanding the effect of 1-D dipping anisotropic conductivity on the response and interpretation of magnetotelluric data
Authors: Darrh Andréa , Li Yaoguo 
Published: April 2022

SUMMARY
Anisotropy in geological settings has been shown to be able to have a significant effect on data and to result in different interpretations when anisotropy is not taken into account. Recent work in inversion of electromagnetic data has emphasized the need for greater accuracy in interpretations where anisotropic effects dominate in data. We focus on how effectively inversions can extract anisotropic characteristics from magnetotelluric (MT) data for the 1-D dipping anisotropy case. We assess the sensitivity of 1-D MT data to each electrical conductivity component by examining the variability of polar plot eccentricity between analytic cases and by examining how sensitivity varies with increasing anisotropic dip angle. We apply a Tikhonov regularized inversion to both synthetic and experimental data using both an L2 norm and an Ekblom norm to approximate an L1 norm to identify the extent to which all model parameters associated with the 1-D dipping anisotropy case are recovered. We find that the application of an L1 norm aids in recovering the true depth extent and horizontal conductivities of an anisotropic layer when compared to the results from a standard L2 norm.
Terrestrial Capabilities of Invasive Fishes and Their Management Implications
Authors: Bressman Noah R 
Published: April 2022

SynopsisAmphibious fishes have many adaptations that make them successful in a wide variety of conditions, including air-breathing, terrestrial locomotor capabilities, and extreme tolerance of poor water quality. However, the traits that make them highly adaptable may allow these fishes to successfully establish themselves outside of their native regions. In particular, the terrestrial capabilities of invasive amphibious fishes allow them to disperse overland, unlike fully aquatic invasive fishes, making their management more complicated. Despite numerous amphibious fish introductions around the world, ecological risk assessments and management plans often fail to adequately account for their terrestrial behaviors. In this review, I discuss the diversity of invasive amphibious fishes and what we currently know about why they emerge onto land, how they move around terrestrial environments, and how they orient while on land. In doing so, I use case studies of the performance and motivations of nonnative amphibious fishes in terrestrial environments to propose management solutions that factor in their complete natural history. Amphibious fish species have established a disproportionate number of nonative populations globally compared to fully aquatic species. Because of their terrestrial capabilities, we may need to manage amphibious fishes more like amphibians than fully aquatic fishes, but to do so, we need to learn more about how these species perform in a wide range of terrestrial environments and conditions.
Repair of coronary sinus shear stress injury following blunt chest trauma using adenosine-induced asystole
Authors: Nazer Rakan I , Mrad Bushr A , Hajjar Waseem M , Albarrati Ali M 
Published: April 2022

Abstract
Blunt chest trauma following a motor vehicle accident is the leading cause of non-penetrating cardiac injuries. Major structural heart injuries are fatal due to acute tamponade. We present the case of a 17-year-old male who was involved in a motor vehicle accident. He had an isolated coronary sinus rupture, which was successfully repaired. We propose a potential mechanism implicated in this rare injury, and we summarize a novel repair technique with adenosine-induced transient asystole.
Right lung torsion diagnosed 6 months after a thoracoscopic right upper lobectomy
Authors: Timane Jon Pedro , Jessen Hansen Henrik , Petersen René Horsleben 
Published: April 2022

Abstract
This report presents the case of a woman successfully treated with thoracoscopic detorsion of the right lung after she was diagnosed with a 180-degree torsion, 6 months after a video-assisted thoracoscopic right upper lobectomy for a stage 1 adenocarcinoma.
Predominance of Severe Plasma Leakage in Pediatric Patients With Severe Dengue in Puerto Rico
Authors: Paz-Bailey Gabriela , Sánchez-González Liliana , Torres-Velasquez Brenda , Jones Emma S , Perez-Padilla Janice , Sharp Tyler M , Lorenzi Olga , Delorey Mark , Munoz-Jordan Jorge L , Tomashek Kay M , Waterman Stephen H , Alvarado Luisa I , Rivera-Amill Vanessa 
Published: April 2022

Abstract

Background
We evaluated clinical and laboratory findings among patients with nonsevere or severe dengue in Puerto Rico to examine whether clinical manifestations vary by age.

Methods
During 2012–2014, we enrolled patients who arrived at the emergency department with fever or history of fever within 7 days of presentation. Serum samples were tested for dengue virus (DENV) by reverse transcriptase-polymerase chain reaction (RT-PCR) and IgM enzyme-linked immunosorbent assay (ELISA). Severe dengue was defined as severe plasma leakage or shock, severe bleeding, or organ involvement at presentation, during hospitalization, or follow-up.

Results
Of 1089 dengue patients identified, 281 (26%) were severe. Compared to those with nonsevere dengue, patients with severe dengue were more often aged 10–19 years (55% vs 40%, P &lt; .001) and hospitalized (87% vs 30%, P &lt; .001). Severe plasma leakage or shock was more common among children aged 0–9 (59%) or 10–19 years (86%) than adults (49%) (P &lt; .01). Severe bleeding was less common among 10–19 year olds (24%) compared to 0–9 year olds (45%) and adults (52%; P &lt; .01).

Conclusions
Severe plasma leakage was the most common presentation among children, highlighting important differences from adults. Vaccination against dengue could help prevent severe dengue among children in Puerto Rico.
Ultrasound-Guided Axillary Brachial Plexus Block for the Management of Graft Site Pain During Dressing Change in the Burn-Injured Patient: A Randomized Control Trial
Authors: Town Cienwen J , Strand Haakan , Johnson James , Van Zundert André 
Published: April 2022

Abstract
Burn injuries requiring split-thickness skin grafting procedures often require ongoing wound aggravation in the form of dressing changes. These dressing changes may cause significant pain due to stimulation of damaged nerve endings in the epidermal layer. A randomized control trial, pilot study, was undertaken to evaluate the impact of ultrasound-guided regional nerve block on the outcome of patient reported pain scores by inpatients requiring dressing changes for hand and upper limb burn injuries. Twenty participants aged &gt;18 years, requiring split-skin grafting for burn injuries of &lt;15% total body surface area were enrolled from a tertiary burns unit between August 2018 and September 2020. Participants were randomized to control (10 participants) or intervention group (10 participants). All participants received analgesia as per their treating team, the intervention group received the addition of an ultrasound-guided axillary brachial plexus block prior to their dressing change procedure. The primary outcome was to assess perceived pain at the graft site as measured by the Numeric Pain Rating Scale (0–10) before, during, and after dressing change procedure. There was strong evidence of a difference in the adjusted mean change score between groups, with a mean reduction of 4.3 in the intervention group, indicating reduced pain, and a mean increase of 1.2 in the control group (P &lt; .001). No adverse events occurred in either group, and the addition of ultrasound-guided regional anesthesia (RA) for the treatment of dressing pain was determined to be a safe and effective intervention.
Carl Akeley’s ‘lost’ decorative taxidermy and anthropomorphic groups
Authors: Alvey Mark , Resleure Tia , Gnoske Thomas P 
Published: April 2022

Abstract
This article provides newly unearthed details about the specimens of taxidermy and anthropomorphic groups produced by Carl Akeley (1864–1926) in his private studio in Milwaukee, Wisconsin, before he embarked on his career in museums. The essay uses Akeley’s decorative work and ‘grotesque groups’ as a springboard to explore the broader context of the rise of decorative taxidermy in the USA in the late nineteenth century, and the influence of European taxidermy on that trend.
Topologies on residuated lattices
Authors: Wang Wei , Zhao Bin 
Published: April 2022

Abstract
The main aim of this paper is to investigate the topologies that constructed by some ideals on residuated lattices and some topologies which induced by lattice ideals and distance functions on involutive residuated lattices. To begin with, we present that prime $\oplus $-ideals and prime $\boxplus $-ideals are coincident on $MTL$-algebras and give some new results about ideals on residuated lattices. In the following, we study an $i$-topology which is induced by an $i$-system on a residuated lattice $A$ and get that $A$ equipped with such an $i$-topology is a topological residuated lattice and give a characterization for such topological involutive residuated lattices. Meanwhile, we give a notion of $\mathcal {I}$-completion of a residuated lattice $A$ with respect to the $i$-topology induced by an $i$-system $\mathcal {I}$ and characterize the $\mathcal {I}$-completion of $A$ by means of the inverse limit of an inverse system. Finally, we show that the topology that induced by a lattice ideal and a distance function on an involutive residuated lattice is a semitopological residuated lattice and which coincides with some $i$-topological residuated lattice when the lattice ideal is an ideal of $A$.
A critique of the literature on past convictions and the probability of guilt
Authors: Hunt Ian 
Published: April 2022

AbstractThis article is a critical review of the growing literature that applies probability analysis to past convictions, in the context of determining guilt in criminal trials. Recent arguments for potentially relaxing rules that exclude past conviction evidence are sustained, but particular flaws and limitations in the theses from Hamer (2019, The significant probative value of tendency evidence. Melbourne University Law Review 42, 506–550) and Redmayne (2015, Character in the criminal trial. Oxford University Press) are exposed. Much of the critique of Redmayne (2015) made by Robinson (2020, Incorporating implicit knowledge into the Bayesian model of prior conviction evidence: some reality checks for the theory of comparative propensity. Law, Probability and Risk 19, 119–137) is dismissed. We should aim to foster a continued lively debate in the literature, gather more data, and narrow the distance between those arguing about theoretical probability analysis and those focused on actual courtroom usage of past conviction evidence.
A non-linear approach to predicting the amplitude and timing of the sunspot area in cycle 25
Authors: Chowdhury Partha , Sarp Volkan , Kilcik Ali , Ray Pratap Chandra , Rozelot Jean-Pierre , Obridko Vladimir N 
Published: April 2022

ABSTRACT
The sunspot cycle waxes and wanes over a period of about 11 years and modulates ‘space weather’. Therefore, predicting the maximum amplitude of the solar cycle is an important goal for both solar physics and space weather. It is clear nowadays that cyclic variations of the Sun are non-linear processes, and thus the above-mentioned goal is difficult to reach with accuracy, albeit several methods currently exist to forecast both long-term and short-term variations. Solar cycle 25 has recently started and knowing the strength and timing of maximum of this cycle in advance is essential. In this study, a non-linear prediction algorithm, non-linear empirical dynamical modelling (EDM), is used to forecast the maximum amplitude and timing of the sunspot area of this cycle. This technique was tested on the last solar cycle 24 (Sarp et al. 2018) and the results obtained are in good agreement with observed values. Our study unveils that the maximum amplitude of the sunspot area of the whole solar disc will be 1606.49 ± 412.78 millionths of the solar hemispheric area (m.s.h.) and is expected to occur around 2025 March. We found that the predicted maximum sunspot areas in the Northern and Southern hemispheres are 731.39 ± 192.7 and 764.89 ± 195.39 m.s.h., respectively, with probable times of maxima around 2023 September and 2024 August, respectively. These results indicate that the strength of the sunspot area in solar cycle 25 will be weaker than or comparable with that in solar cycle 24. Such results are discussed and compared with other recent forecasts.
Probing for the host galaxies of the fast X-ray transients XRT 000519 and XRT 110103
Authors: Eappachen D , Jonker P G , Fraser M , Torres M A P , Dhillon V S , Marsh T , Littlefair S P , Quirola-Vásquez J , Maguire K , Mata Sánchez D , Cannizzaro G , Kostrzewa-Rutkowska Z , Wevers T , Onori F , Inkenhaag Anne , Brennan S J 
Published: April 2022

ABSTRACT
Over the past few years, ∼30 extragalactic fast X-ray transients (FXRTs) have been discovered, mainly in Chandra and XMM-Newton data. Their nature remains unclear, with proposed origins, including a double neutron star merger, a tidal disruption event involving an intermediate-mass black hole and a white dwarf, or a supernova shock breakout. A decisive differentiation between these three promising mechanisms for their origin requires an understanding of the FXRT energetics, environments, and/or host properties. We present optical observations obtained with the Very Large Telescope for the FXRTs XRT 000519 and XRT 110103 and Gran Telescopio Canarias observations for XRT 000519 designed to search for host galaxies of these FXRTs. In the gs, rs, and R-band images, we detect an extended source on the north-west side of the $\sim \, 1^{\prime \prime }$ (68 per cent confidence) error circle of the X-ray position of XRT 000519 with a Kron magnitude of gs = 26.29 ± 0.09 (AB magnitude). We discuss the XRT 000519 association with the probable host candidate for various possible distances, and we conclude that if XRT 000519 is associated with the host candidate a supernova shock breakout scenario is likely excluded. No host galaxy is found near XRT 110103 down to a limiting magnitude of R &gt; 25.8.
A semi-analytical solution to the forward–reverse shock hydrodynamics of the gamma-ray burst afterglow
Authors: Zhang Ze-Lin , Liu Ruo-Yu , Geng Jin-Jun , Wu Xue-Feng , Wang Xiang-Yu 
Published: April 2022

ABSTRACT
We extend the standard model of forward–reverse shock (FS–RS) for gamma-ray burst (GRB) afterglow to more general cases. On one hand, we derive the analytical solution to the hydrodynamics of the shocks in two limiting cases, i.e. an ultrarelativistic reverse shock case and a Newtonian reverse shock case. Based on the asymptotic solutions in these two limiting cases, we constitute a semi-analytical solution for the hydrodynamics of the shocks in the generic case, covering the mildly relativistic reverse shock case. On the other hand, we derive the evolution of the system taking into account the condition of energy conservation which is not satisfied in the standard FS–RS model. A generic solution of semi-analytical expressions is also given. In both the extended standard FS–RS model (satisfying pressure balance condition) and the model satisfying energy conservation, we find that the results in the ultrarelativistic reverse shock case and in the early stage of the Newtonian reverse shock case are different from those in the standard FS–RS model by only a factor that close to one while the same initial conditions adopted. However, the asymptotic solutions in the limiting cases are not good approximations to those in the intermediate case. Our semi-analytical results agree well with the numerical results for a large range of model parameters, and hence can be easily employed to diagnose the physical quantities of the GRB shell and circumburst environment.
Globular Cluster UVIT Legacy Survey (GlobULeS) – I. FUV–optical colour–magnitude diagrams for eight globular clusters
Authors: Sahu Snehalata , Subramaniam Annapurni , Singh Gaurav , Yadav Ramakant , Valcarce Aldo R , Choudhury Samyaday , Rani Sharmila , Prabhu Deepthi S , Chung Chul , Côté Patrick , Leigh Nathan , Geller Aaron M , Chatterjee Sourav , Kameswara Rao N , Bandyopadhyay Avrajit , Shara Michael , Dalessandro Emanuele , Pandey Gajendra , Postma Joesph E , Hutchings John , Simunovic Mirko , Stetson Peter B , Thirupathi Sivarani , Puzia Thomas , Sohn Young-Jong 
Published: April 2022

ABSTRACT
We present the first results of eight globular clusters (GCs) from the AstroSat/UVIT Legacy Survey programme GlobULeS based on the observations carried out in two far-ultraviolet (FUV) filters (F148W and F169M). The FUV–optical and FUV–FUV colour–magnitude diagrams (CMDs) of GCs with the proper motion membership were constructed by combining the Ultra-Violet Imaging Telescope (UVIT) data with Hubble Space Telescope (HST) UV Globular Cluster Survey data for inner regions and Gaia Early Data Release for regions outside the HST’s field. We detect sources as faint as F148W ∼ 23.5 mag, which are classified based on their locations in CMDs by overlaying stellar evolutionary models. The CMDs of eight GCs are combined with the previous UVIT studies of three GCs to create stacked FUV–optical CMDs to highlight the features/peculiarities found in the different evolutionary sequences. The FUV (F148W) detected stellar populations of 11 GCs comprise 2816 horizontal branch (HB) stars [190 extreme HB (EHB) candidates], 46 post-HB (pHB), 221 blue straggler stars (BSSs), and 107 white dwarf (WD) candidates. We note that the blue HB colour extension obtained from F148W − G colour and the number of FUV detected EHB candidates are strongly correlated with the maximum internal helium (He) variation within each GC, suggesting that the FUV–optical plane is the most sensitive to He abundance variations in the HB. We discuss the potential science cases that will be addressed using these catalogues including HB morphologies, BSSs, pHB, and WD stars.
SWORD2: hierarchical analysis of protein 3D structures
Authors: Cretin Gabriel , Galochkina Tatiana , Vander Meersche Yann , de Brevern Alexandre G , Postic Guillaume , Gelly Jean-Christophe 
Published: April 2022

Abstract
Understanding the functions and origins of proteins requires splitting these macromolecules into fragments that could be independent in terms of folding, activity, or evolution. For that purpose, structural domains are the typical level of analysis, but shorter segments, such as subdomains and supersecondary structures, are insightful as well. Here, we propose SWORD2, a web server for exploring how an input protein structure may be decomposed into ‘Protein Units’ that can be hierarchically assembled to delimit structural domains. For each partitioning solution, the relevance of the identified substructures is estimated through different measures. This multilevel analysis is achieved by integrating our previous work on domain delineation, ‘protein peeling’ and model quality assessment. We hope that SWORD2 will be useful to biologists searching for key regions in their proteins of interest and to bioinformaticians building datasets of protein structures. The web server is freely available online: https://www.dsimb.inserm.fr/SWORD2.
TIRSF: a web server for screening gene signatures to predict Tumor immunotherapy response
Authors: Chen Li , Chen Tianjian , Zhang Ya , Lin Haichen , Wang Ruihan , Wang Yihang , Li Hongyu , Zuo Zhixiang , Ren Jian , Xie Yubin 
Published: April 2022

Abstract
Immune checkpoint blockade (ICB) therapy has been successfully applied to clinically therapeutics in multiple cancers, but its efficacy varies greatly among different patients and cancer types. Therefore, the construction of gene signatures to identify patients who could benefit from ICB therapy is particularly important for precision cancer treatment. However, due to the lack of a user-friendly platform, the construction of such gene signatures is a great challenge for clinical investigators who have limited programming skills. In light of this challenge, we developed a web server called Tumor Immunotherapy Response Signature Finder(TIRSF) for the construction of gene signatures to predict ICB therapy response in cancer patients. TIRSF consists of three functional modules. The first module is the Signature Discovery module which provides signature construction and performance evaluation functionalities. The second is a module for response prediction based on the TIRSF signatures, which enables response prediction and prognostic analysis of immunotherapy samples. The last is a module for response prediction based on existing signatures. This module currently integrates 24 published signatures for ICB therapy response prediction. Together, all of above features can be freely accessed at http://tirsf.renlab.org/.
Cancer driver drug interaction explorer
Authors: Hartung Michael , Anastasi Elisa , Mamdouh Zeinab M , Nogales Cristian , Schmidt Harald H H W , Baumbach Jan , Zolotareva Olga , List Markus 
Published: April 2022

AbstractCancer is a heterogeneous disease characterized by unregulated cell growth and promoted by mutations in cancer driver genes some of which encode suitable drug targets. Since the distinct set of cancer driver genes can vary between and within cancer types, evidence-based selection of drugs is crucial for targeted therapy following the precision medicine paradigm. However, many putative cancer driver genes can not be targeted directly, suggesting an indirect approach that considers alternative functionally related targets in the gene interaction network. Once potential drug targets have been identified, it is essential to consider all available drugs. Since tools that offer support for systematic discovery of drug repurposing candidates in oncology are lacking, we developed CADDIE, a web application integrating six human gene-gene and four drug-gene interaction databases, information regarding cancer driver genes, cancer-type specific mutation frequencies, gene expression information, genetically related diseases, and anticancer drugs. CADDIE offers access to various network algorithms for identifying drug targets and drug repurposing candidates. It guides users from the selection of seed genes to the identification of therapeutic targets or drug candidates, making network medicine algorithms accessible for clinical research. CADDIE is available at https://exbio.wzw.tum.de/caddie/ and programmatically via a python package at https://pypi.org/project/caddiepy/.