bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on structural geometry and dynamic property of [NH3(CH2)5NH3]CdCl4 crystal at phases I, II, and III
Authors: Lim Ae Ran , Joo Yong Lak 
Published: March 2022

AbstractOrganic–inorganic hybrid perovskites can potentially be used in electrochemical devices, such as batteries and fuel cells. In this study, the structure and phase transition temperatures of the organic–inorganic material [NH3(CH2)5NH3]CdCl4 crystal were confirmed by X-ray diffraction and differential scanning calorimetry. From the nuclear magnetic resonance results, the crystallographic configurations of 1H, 13C, and 14N in the cation changed at temperatures close to TC1 (336 K), whereas that of 113Cd in the anion shows significant changes at temperatures close to TC1 and TC2 (417 K). The activation energy, Ea, values for 1H and 13C obtained from the spin–lattice relaxation time, T1ρ, below and above TC1 were evaluated, where the Ea value for 13C was more flexible at low temperatures than at high temperatures. In addition, the effect on molecular motion was effective at high temperatures. The phase transition at 336 K was associated with the change in the N–H···Cl bond due to the change in the coordination geometry of Cl around Cd in the CdCl6 anion. On the other hand, the phase transition at 417 K was related to the ferroelastic phase transition attributed to the twin domains.
Association between asthma or chronic obstructive pulmonary disease and chronic otitis media
Authors: Kim Sung Kyun , Hong Seok Jin , Yoo Dae Myoung , Min Chanyang , Choi Hyo Geun 
Published: March 2022

AbstractWe hypothesized that asthma/chronic obstructive pulmonary disease (COPD) might increase the risk of chronic otitis media (COM), as asthma or COPD affects other diseases. The aim of this research was to investigate whether the incidence of COM is affected by a diagnosis of asthma or COPD in patients compared to matched controls from the national health screening cohort. A COM group (n = 11,587) and a control group that was 1:4 matched for age, sex, income, and residence area (n = 46,348) were selected. The control group included participants who never received treatment for COM from Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2015. The crude and adjusted odds ratios (ORs) of previous asthma/COPD before the index date for COM were analyzed using conditional logistic regression. The analyses were stratified by age, sex, income, and region of residence. The period prevalence of asthma (17.5% vs. 14.3%, p < 0.001) and COPD (6.6% vs. 5.0%, p < 0.001) were significantly higher in the COM group than in the control group. In addition, the odds of asthma and COPD were significantly higher in the COM group than in the control group. Both asthma (adjusted OR 1.23, 95% confidence interval [CI] 1.16–1.31, p < 0.001) and COPD (adjusted OR 1.23, 95% CI 1.13–1.35, p < 0.001) increased the ORs for COM. This positive association between asthma/COPD and COM indicates that asthma/COPD might increase the incidence of COM.
Dysfunction of lipid storage droplet-2 suppresses endoreplication and induces JNK pathway-mediated apoptotic cell death in Drosophila salivary glands
Authors: Binh Tran Duy , Nguyen Yen D. H. , Pham Tuan L. A. , Komori Kenichi , Nguyen Thanh Q. C. , Taninaka Masahide , Kamei Kaeko 
Published: March 2022

AbstractThe lipid storage droplet-2 (LSD-2) protein of Drosophila is a homolog of mammalian perilipin 2, which is essential for promoting lipid accumulation and lipid droplet formation. The function of LSD-2 as a regulator of lipolysis has also been demonstrated. However, other LSD-2 functions remain unclear. To investigate the role of LSD-2, we performed tissue-specific depletion in the salivary glands of Drosophila using a combination of the Gal4-upstream activating sequence system and RNA interference. LSD-2 depletion inhibited the entry of salivary gland cells into the endoreplication cycle and delayed this process by enhancing CycE expression, disrupting the development of this organ. The deficiency of LSD-2 expression enhanced reactive oxygen species production in the salivary gland and promoted JNK-dependent apoptosis by suppressing dMyc expression. This phenomenon did not result from lipolysis. Therefore, LSD-2 is vital for endoreplication cell cycle and cell death programs.
The magnetic topology of the inverse Evershed flow
Authors: Prasad A. , Ranganathan M. , Beck C. , Choudhary D. P. , Hu Q. 
Published: March 2022

Context. The inverse Evershed flow (IEF) is a mass motion towards sunspots at chromospheric heights.
Aims. We combined high-resolution observations of NOAA 12418 from the Dunn Solar Telescope and vector magnetic field measurements from the Helioseismic and Magnetic Imager (HMI) to determine the driver of the IEF.
Methods. We derived chromospheric line-of-sight (LOS) velocities from spectra of Hα and Ca II IR. The HMI data were used in a non-force-free magnetic field extrapolation to track closed field lines near the sunspot in the active region. We determined their length and height, located their inner and outer foot points, and derived flow velocities along them.
Results. The magnetic field lines related to the IEF reach on average a height of 3 megameter (Mm) over a length of 13 Mm. The inner (outer) foot points are located at 1.2 (1.9) sunspot radii. The average field strength difference ΔB between inner and outer foot points is +400 G. The temperature difference ΔT is anti-correlated with ΔB with an average value of −100 K. The pressure difference Δp is dominated by ΔB and is primarily positive with a driving force towards the inner foot points of 1.7 kPa on average. The velocities predicted from Δp reproduce the LOS velocities of 2–10 km s−1 with a square-root dependence.
Conclusions. We find that the IEF is driven along magnetic field lines connecting network elements with the outer penumbra by a gas pressure difference that results from a difference in field strength as predicted by the classical siphon flow scenario.
Bibliometrische Analyse von Forschungsgebieten, Publikationshierarchie und Autorengeschlecht der deutschen universitären Unfallchirurgie und Orthopädie
Authors: Preut Jennifer , Frosch Karl-Heinz , Debus Eike Sebastian , Grundmann Reinhart T. 
Published: March 2022

Zusammenfassung
Hintergrund Ziel der vorliegenden bibliometrischen Untersuchung war es, Publikationsschwerpunkte, Studienart und Publikationsaktivitäten in Abhängigkeit von Hierarchiestufe und
Geschlecht des Autors deutscher unfallchirurgischer Universitätskliniken zu erfassen.
Material und Methodik Die Publikationsaktivitäten von Chef- und Oberärzten, Sektions- und Bereichsleitern von 39 deutschen unfallchirurgischen Universitätskliniken wurden für einen
10-Jahres-Zeitraum (1. Januar 2010 bis 31. Dezember 2019) erfasst. Berücksichtigt wurden alle Publikationen, die in PubMed gelistet waren und bei denen die entsprechenden Personen Erst- oder
Letztautor waren. Zusätzlich wurden der Impactfaktor (IF) und der h-Index bestimmt.
Ergebnisse 1739 (39,2%) Publikationen wurden von 180 Mitarbeitern der Universitätskliniken für Unfallchirurgie, 2699 (60,8%) von 343 Mitarbeitern der Kliniken für Unfallchirurgie und
Orthopädie erstellt. Am häufigsten bezogen sich die Publikationen auf Verletzungen bzw. Beeinträchtigungen der unteren Extremität inkl. Hüfte (n = 1626; 38,1%), gefolgt von der oberen
Extremität (n = 737; 17,3%). Der Schwerpunkt der Veröffentlichungen lag auf der Diagnostik (25,5%), gefolgt von Veröffentlichungen zur Operationstechnik (19,1%) und zu speziellen
Osteosynthesen (16,9%). Den höchsten durchschnittlichen IF pro Publikation erzielten Publikationen zu Plastiken (IF 2,02), zum Outcome (IF 1,96) und zur Diagnostik (IF 1,93). Direktoren
waren in 18,8%, Oberärzte mit Leitungsfunktion in 40,7% und Oberärzte ohne Leitungsfunktion in 69% Erstautoren und umgekehrt in 81,2%, 49,3% und 31,0% Letztautoren. 64 von 523 Mitgliedern
der Führungsmannschaft (12,2%) waren Frauen. Mit insgesamt 306 Autorschaften (6,1%) und mit 4,8 Autorschaften pro Mitarbeiterin publizierten sie signifikant weniger als die männlichen
Mitarbeiter (10,3 Autorschaften pro Mitarbeiter).
Folgerung In der vorliegenden Untersuchung machte bei den Oberärzten mit Leitungsfunktion der Anteil publizierender Mitarbeiter bei den Frauen 59,1%, bei den Männern aber 85,5% aus,
bei Oberärzten ohne Leitungsfunktion unterschieden sich Frauen und Männer hingegen nur geringfügig in dem Anteil publizierender Mitarbeiter (57,5% vs. 60,5%). Ob demnach mit der Dauer des
Berufslebens die Anforderungen von Familie und Beruf von Frauen schwerer als von Männern zu erfüllen sind, muss hinterfragt werden. Mentoringprogramme sind zu fordern, um die
Publikationsaktivität der in Zukunft zunehmenden Zahl weiblicher Bewerber vermehrt zu unterstützen.
Die SARS-CoV-2-Pandemie in Altenpflegeheimen: Erkenntnisse und
Analysen in Frankfurt am Main von März 2020 bis September
2021
Authors: Heudorf Ursel , Gottschalk Rene , Müller Maria , Steul Katrin Simone 
Published: March 2022

Zusammenfassung
Hintergrund Bewohner von Altenpflegeheimen sind von der Corona-Pandemie
besonders betroffen. Daten aus der ersten Welle der Pandemie zeigen, dass in
vielen Ländern 30–70% aller Todesfälle an oder
mit SARS-CoV-2 Altenpflegeheimbewohner betreffen, obwohl deren Anteil in der
Bevölkerung in der Regel weniger als 1% ausmacht. Nachfolgend
werden die Erkenntnisse aus den Altenpflegeheimen (APH) in Frankfurt am Main
(März 2020-September 2021) vorgestellt und im Hinblick auf erforderliche
Verbesserungen diskutiert.
Material und Methoden Die Meldungen von SARS-CoV-2 Nachweisen im PCR-Test
von Bewohnern und Mitarbeitern in den APHs in Frankfurt am Main und die
erfragten Symptome, wurden deskriptiv ausgewertet. Darüber hinaus wurden
die Gesamtsterbefälle der Altenpflegeheime von 2018 bis Juni 2021
jeweils pro Quartal erfragt.
Ergebnisse In der ersten Welle (März-Mai 2020) wurden in Frankfurt
am Main 111 SARS-CoV-2 positive APH-Bewohner gemeldet, wovon 40%
asymptomatisch waren, 48% hospitalisiert wurden und 23%
verstarben. In den weiteren Phasen bis 30.09.2021 wurden weitere 1196 infizierte
Bewohner gemeldet. Diese waren meist asymptomatisch infiziert (70%),
insgesamt weniger schwer erkrankt und seltener hospitalisiert (27%).
Auch die Sterberate war mit 17,6% geringer als während der
ersten Phase. Die Gesamtsterblichkeit in den Frankfurter APH lag im Jahr 2020 um
7,6% höher als in 2019 und 1,1% höher als im
„Grippejahr“ 2018.
Diskussion Im Gegensatz zur ersten Welle, als nur wenige APH-Bewohner an
COVID-19 erkrankten, konnten in der zweiten Pandemiewelle im
Herbst/Winter 2020/21 bei hohen Inzidenzen in der
Allgemeinbevölkerung SARS-CoV-2-Einträge und
–Ausbrüche in den APH in Frankfurt nicht verhütet werden
–trotz umfangreicher Hygiene-, Infektionspräventions- und
Kontaktminderungsmaßnahmen (u. a.
Besuchseinschränkungen), die die Lebensqualität und
Persönlichkeitsrechte der Bewohner massiv einschränkten. Erst
mit zunehmender Impfrate bei Bewohnern und Mitarbeitern ab April 2021 kam es nur
noch zu einzelnen Einträgen; Ausbrüche traten nicht mehr auf.
Zum besseren Schutz der hochvulnerablen Altenpflegeheimbewohner wurde eine
angemessene Balance gefordert zwischen Infektionsschutz und der Vermeidung von
Kollateralschäden durch bestmögliche Aufrechterhaltung der
Freiheit und Lebensqualität der Altenpflegeheimbewohner.
Acquired Chiari Type I Malformation Associated with Type IV Dural Arteriovenous Fistula: Case Report
Authors: Luy Diego D. , Agarwal Nitin , McDowell Michael M. , Tonetti Daniel A. , Goldschmidt Ezequiel , Friedlander Robert M. 
Published: March 2022

Abstract
Background Chiari malformations, usually congenital, can rarely be associated with arteriovenous (AV) fistulas. We present the first case involving a type IV dural AV fistula with a Chiari type I malformation.
Methods Retrospective chart review was performed to obtain pertinent details regarding history and examination, pathologic findings, and treatment course.
Results A 63-year-old woman with a 2-year history of migraines presented with 5 months of occipital, right-sided headaches and neck pain exacerbated by Valsalva maneuvers. Computed tomography (CT) and magnetic resonance imaging (MRI) of the head showed a possible right occipital AV malformation, bilateral cerebellar subdural hygromas, and tonsillar crowding at the foramen magnum indicating an acquired Chiari type I malformation. Angiography demonstrated a Cognardtype IV right posterior occipital dural AV fistula supplied by bilateral middle meningeal and posterior meningeal arteries.
Conclusion After treatment of the dural AV fistula, hygroma evacuation, and decompression of the acquired Chiari malformation, the patient's Valsalva-induced headaches abated.
High-speed Training in a Specific Context in Soccer: Transition
Games
Authors: Asian-Clemente Jose A. , Rabano-Muñoz Alberto , Requena Bernardo , Suarez-Arrones Luis 
Published: March 2022

AbstractThe aims of this study were to compare the load of three tasks designed to train
features of soccer: a transition game, a small-sided game with a change of
playing area, and a large-sided game. Twenty young elite players performed these
tasks. Variables measured were total distance covered (DC), distance covered at
14.0–17.9 km·h−1 (DC
14.0–17.9 km·h−1), distance
covered at 18.0–21 km·h−1 (DC
18–21 km·h−1), distance covered
> 21 km·h−1
(DC>21 km·h−1), peak speed,
accelerations and decelerations > 1.0 and
> 2.5 m·s−2, player load,
and rate of perceived exertion. Transition games produced greater DC
18–21 km·h−1,
DC>21 km·h−1, peak speed and
Acc>2.5 m·s−2 than the other
drills (p<0.01) and higher DC
14–17.9 km·h−1 (p<0.01),
Dec>1 m·s−2 (p<0.05) and
Dec>2.5 m·s−2 (p<0.01)
than the large-sided game. Both sided games produced more DC (p<0.01),
Acc>1 m·s−2 (p<0.01) and
player load (p<0.01 and p<0.05, respectively) than the
transition game. During the small-sided game, significantly higher DC
14–17.9 km·h−1, DC
18–21 km·h−1 and
DC>21 km·h−1 were recorded in
comparison with the large-sided game (p<0.01). The studied parameters
showed lower variation in the transition game. Coaches could use transition
games to train high speed running in counter-attack contexts.
Intraneural Ganglion of the Peroneal Nerve—A Rare Cause of Pediatric Peroneal Nerve Palsy: A Case Report
Authors: Bucher Florian , Maerz Vincent , Obed Doha , Vogt Peter M. , Weyand Birgit 
Published: March 2022

AbstractIntraneural ganglia are benign mucinous cysts located within the epineurium of a peripheral nerve. The pathogenesis and formation of intraneural ganglia are controversial. The main theories described in the literature are of degenerative, synovial or de novo occurrence. We present the case of a 14-year-old boy who presented in our outpatient clinic with a complaint of interdigital neuralgia between hallux and second toe, as well as left foot drop. MRI examination showed a hyperintense cystic distension of the common peroneal nerve measuring 130 mm × 5 mm extending from the poplitea to the anterior compartment of the leg. We performed microscopic decompression and neurolysis surgery. The cyst showed a sac-like distension at its distal end with connection to the tibiofibular joint and was resected. After 8 weeks, postoperatively, the boy claimed to be pain-free and slight recovery of the superficial peroneal nerve was noticed. At 6 months postoperative, the patient showed a continuous improvement of motor function, demonstrating foot eversion with 3/5 muscle strength and foot extension with 2/5 muscle strength. Intraneural ganglia reported for pediatric patients represent a very rare entity. To the best of our knowledge, less than 15 cases have been described within the English-speaking literature.
Longitudinally Extensive Transverse Myelitis: One Disease, Variable Outcomes—A Case Series
Authors: Chandrasekar Shyam , John Joseph , Satapathy Amit Kumar 
Published: March 2022

Abstract
Longitudinal extensive transverse myelitis (LETM) is a rare form of widespread inflammation of the spinal cord causing T2 hyperintensity in spinal magnetic resonance imaging (MRI) extending across three or more vertebral segments. It is an acute onset of sensory, motor, and autonomic dysfunction of variable etiology with a likely poor outcome. We present a case series of three cases wherein children between the ages of 4 and 13 years had diverse symptoms from gradual painless loss of vision in both eyes with headache, vomiting and seizure, and a normal central nervous system examination except involvement of the optic nerve to another child with abdominal pain, urinary retention and constipation for 3 days with exaggerated DTR, and patchy sensory loss without any definite sensory level, and to the third child with fever and weakness of lower limbs, hypotonia and grade 1–2/5 power in lower limbs and normal upper limb power. Contrast-enhanced MRI spine of all children showed long segment T2 hyperintensity with variable involvement of the brain. The first two children were treated with pulsed dose methylprednisolone, and the last child received intravenous immunoglobulin followed by methylprednisolone. All were followed with oral prednisolone. LETM has a varied presentation with different etiologies. Antineuromyelitis optica immunoglobulin G (IgG) antibody (Aquaporin-4 IgG) and antimyelin oligodendrocyte glycoprotein antibody are strongly recommended though they may not be locally available or not affordable. Early and aggressive immunomodulatory therapy may help faster recovery, as did with two of our three children.
Design and Evaluation of a Postpartum Depression Ontology
Authors: Morse Rebecca B. , Bretzin Abigail C. , Canelón Silvia P. , D'Alonzo Bernadette A. , Schneider Andrea L. C. , Boland Mary R. 
Published: March 2022

Abstract
Objective Postpartum depression (PPD) remains an understudied research area despite its high prevalence. The goal of this study is to develop an ontology to aid in the identification of patients with PPD and to enable future analyses with electronic health record (EHR) data.
Methods We used Protégé-OWL to construct a postpartum depression ontology (PDO) of relevant comorbidities, symptoms, treatments, and other items pertinent to the study and treatment of PPD.
Results The PDO identifies and visualizes the risk factor status of variables for PPD, including comorbidities, confounders, symptoms, and treatments. The PDO includes 734 classes, 13 object properties, and 4,844 individuals. We also linked known and potential risk factors to their respective codes in the International Classification of Diseases versions 9 and 10 that would be useful in structured EHR data analyses. The representation and usefulness of the PDO was assessed using a task-based patient case study approach, involving 10 PPD case studies. Final evaluation of the ontology yielded 86.4% coverage of PPD symptoms, treatments, and risk factors. This demonstrates strong coverage of the PDO for the PPD domain.
Conclusion The PDO will enable future researchers to study PPD using EHR data as it contains important information with regard to structured (e.g., billing codes) and unstructured data (e.g., synonyms of symptoms not coded in EHRs). The PDO is publicly available through the National Center for Biomedical Ontology (NCBO) BioPortal (
https://bioportal.bioontology.org/ontologies/PARTUMDO
) which will enable other informaticists to utilize the PDO to study PPD in other populations.
Fratura isolada de Tillaux em adulto – Revisão da literatura com base em um relato de caso raro
Authors: da Silva Nuno Vieira , Esteves Ana , Ribeiro Pedro , Miradouro José , Pereira Joana , Marinheiro Julio 
Published: March 2022

ResumoA fratura isolada de Tillaux representa uma rara e frequentemente mal diagnosticada fratura de tíbia distal anterolateral em adultos. Normalmente ocorre em adolescentes que se aproximam da maturidade esquelética por avulsão do ligamento tibiofibular anteroinferior. Este estudo de revisão de literatura baseada em caso tem como objetivo lembrar a existência dessa identidade em adultos, resumir seu mecanismo de lesão, diagnóstico e procedimentos de tratamento. De acordo com a literatura, este é apenas o oitavo caso descrito: uma mulher de 46 anos sofreu uma fratura isolada de Tillaux com 4 mm de deslocamento e realizaram-se redução e fixação aberta com parafuso canulado duplo. Após a reabilitação adequada, alcançou-se um excelente desfecho funcional e radiológico. É importante reconhecer e tratar adequadamente essas lesões distintas para evitar maiores instabilidades, alterações degenerativas e limitação da função articular do tornozelo. Um diagnóstico precoce e a osteossíntese apropriada desempenham um papel significativo em um prognóstico de recuperação bem-sucedido.
Minipterional Approach for Middle Fossa Skull Base Lesions: Technical Note
Authors: Mura Jorge M. , Rabelo Nícollas N. , Telles Joao P. M. , Poblete Tomás , Hernández-Álvarez Víctor , Muñoz Sebastián , Figueiredo Eberval G. 
Published: March 2022

AbstractSurgical access to the middle fossa can be technically challenging. As neurosurgery evolves to minimally invasive approaches, the objective of this study is to demonstrate the extension of the Minipterional approach to access the middle fossa. We present a new surgical approach to the middle fossa for the treatment of secondary trigeminal neuralgia. Three cases are reported to illustrate the following techniques: a patient with petrotentorial meningioma and trigeminal neuralgia, a patient with an arachnoid cyst compressing the fifth nerve, and a patient with a middle cerebral artery aneurysm and a long history of TN (trigeminal neuralgia) refractory to medical and surgical treatments. All three experienced full symptom controls with no permanent neurological deficits. Therefore, the Minipterional technique might represent a feasible, effective, and safe option to treat refractory secondary TN. It also allows approaching these lesions when the posterior fossa approach is compromised by anatomical distortion and enables the simultaneous treatment of secondary trigeminal neuralgia and other lesions, such as aneurysms and meningiomas.