bluuebunny/crossref_metadata_2025_split huggingface dataset:
The lexicographical approach to remittere in the Thesaurus linguae Latinae (compared with dimittere and mittere)
Authors: Schrickx Josine 
Published: January 2022

Abstract
One problem of all existing Latin dictionaries is that the text corpus was too limited to give a comprehensive semantic picture of a lemma. In the Thesaurus linguae Latinae (TLL) the database is much more extensive: the corpus of the TLL consists of all surviving texts up to ca. 600 CE. For the time up to ca. 200 CE all evidence is taken into account, for the time after that a selection. Here, using the recently written article remitto, it is shown how an article is constructed and what the criteria of the groups are. Thus, this paper gives guidance on how to interpret a TLL article. It also compares remitto, published in 2021, with the simplex mitto, published in 1957, and with dimitto, published in 1913. It turns out that the lemma remittere has three main groups that correspond exactly to the three main groups of mittere: ‘send’, ‘throw’ and ‘let go’. The criteria of these three main groups can be described as follows: ‘command or cause a movement’ (‘send’), ‘perform a movement action’ (‘throw’) and ‘allow a movement’ (‘let go’). In remittere we accordingly find: ‘to send back’, ‘to throw back’, and ‘to let go (back)’. This last meaning is the largest and overlaps with dimittere. However, remittere can also mean ‘to relax’, which we do not see in the earlier article dimitto.
Word-final-sin Ennius’Annales: a sociolinguistic approach
Authors: Zair Nicholas 
Published: January 2022

AbstractIn Ennius’Annales, as in other Roman poetry of the third, second, and to some extent first centuries BC, a word-final syllable consisting of a short vowel followed by-scan scan as light even when followed by a word beginning with a consonant. In theAnnales, light scansion is the norm in the second part of the foot (thesis), but heavy scansion is found four times. I argue that attempts to emend away these instances of heavy scansion are not founded on strong arguments. Rather, the infrequency of final-smaking position in thesis can be put down to the sociolinguistic situation of the time, in which deletion or weakening of final-sco-existed with its presence, with the latter being characteristic of more formal speech.
Successful use of cinacalcet monotherapy in the management of siblings with homozygous calcium-sensing receptor mutation
Authors: Wade Laura , Aindow Anita , Isherwood Lorraine , Mughal M. Zulf , Ramakrishnan Renuka 
Published: January 2022

Abstract

Objectives
Neonatal severe hyperparathyroidism (NSHPT) due to pathogenic mutations in the calcium-sensing receptor (CASR) is a serious medical condition that can lead to symptomatic hypercalcaemia and has detrimental effects on a child’s growth and development. What is new: This report adds to evidence that homozygous CASR mutations can be managed with cinacalcet monotherapy as an alternative to parathyroidectomy. And, early use of cinacalcet in NSHPT can result in improvements in symptoms, growth and developmental milestones.

Case presentation
We present two siblings with NSHPT due to homozygous mutation in the CASR gene with moderate hypercalcaemia. Both were treated with cinacalcet monotherapy and showed significant improvement in growth parameters including head circumference, developmental milestones and hypercalcaemic symptoms, once their calcium and parathyroid hormone levels normalised.

Conclusions
This report highlights the role of cinacalcet in managing elevated serum calcium levels in a select group of infants with NSHPT due to homozygous CASR mutations, resulting in improvement in hypercalcaemic symptoms, growth and neurodevelopmental outcomes.
Experience with direct oral anticoagulants in pregnancy – a systematic review
Authors: Areia Ana Luísa , Mota-Pinto Anabela 
Published: January 2022

Abstract

Objectives
The experience and use of the new direct oral anti coagulants (DOACs) in pregnancy is limited, but as they offer many practical advantages compared to low molecular weight heparin (LMWH), the pursue of their safety is challenging.

Methods
Systematic review of studies in which DOACs were used during pregnancy and the puerperal period (PROSPERO registry-CRD42021237688). Searches were performed on MEDLINE, Embase, Scopus, Web of Science, and Cochrane Library databases, until July 2021 and secondary sources using the MeSH terms ‘pregnancy’, ‘pregnancy complications’, ‘venous thrombosis’, ‘congenital abnormalities’, ‘Factor Xa Inhibitors,’ and names of specific DOACs. Search was limited to human studies, with English or French as languages of report.

Results
Literature search yielded 1,989 results which, after duplicate exclusion, resulted in 672 publications. Studies were then screened using the specified eligibility criteria described and studies that did not meet the criteria were excluded, resulting in 21 full text studies to an in-depth analysis and data extraction. Overall, 339 cases of DOACs usage during pregnancy were reported until now. The data demonstrated 56% live births but a miscarriage rate of 22.2% and an elective termination of pregnancy in 21.8%; fetal abnormalities related to DOACs occurred in 3.6%. Our meta-analysis displayed a higher rate of fetal loss and fetal abnormalities with DOACs use compared to LMWH, notwithstanding similar bleeding complications.

Conclusions
The current information available for the 339 cases herein reported does not allow a conclusion that DOACs can be safely used in pregnancy.
Pericentric inversion of chromosome 6 and male fertility problems
Authors: Fan Haitao , Liu Zhe , Zhan Peng , Jia Guoliang 
Published: January 2022

Abstract
As a significant chromosomal structural abnormality, chromosomal inversion is closely related to male infertility. For inversion carriers, the interchromosomal effect explains male infertility, but its specific mechanism remains unclear. Additionally, inversion carriers with different chromosomes have different clinical manifestations. Therefore, genetic counseling is difficult in clinical practice. Herein, four male carriers of pericentric inversion in chromosome 6 have been described. Two patients showed asthenospermia, one showed azoospermia, and the wife of the remaining patient had recurrent miscarriages. Through a literature search, the association between the breakpoint of pericentric inversion in chromosome 6 and male fertility problems are also discussed in this study. Overall, important genes related to asthenospermia in chromosome 6p21 were found, which may be related to the clinical phenotype. These results suggest that physicians should focus on the breakpoints of inversion in genetic counseling.
Computational spectrometers enabled by nanophotonics and deep learning
Authors: Gao Li , Qu Yurui , Wang Lianhui , Yu Zongfu 
Published: January 2022

Abstract
A new type of spectrometer that heavily relies on computational technique to recover spectral information is introduced. They are different from conventional optical spectrometers in many important aspects. Traditional spectrometers offer high spectral resolution and wide spectral range, but they are so bulky and expensive as to be difficult to deploy broadly in the field. Emerging applications in machine sensing and imaging require low-cost miniaturized spectrometers that are specifically designed for certain applications. Computational spectrometers are well suited for these applications. They are generally low in cost and offer single-shot operation, with adequate spectral and spatial resolution. The new type of spectrometer combines recent progress in nanophotonics, advanced signal processing and machine learning. Here we review the recent progress in computational spectrometers, identify key challenges, and note new directions likely to develop in the near future.
Green synthesis of various saturated S-heterocyclic scaffolds: an update
Authors: Virendra Sharma Arvind , Wahan Simranpreet K. , Sahu Chandrakant , Chawla Pooja A. 
Published: January 2022

Abstract
Development of reliable and eco-friendly novel schemes for the synthesis of organic compounds is an important step in the field of organic and medicinal chemistry. Green chemistry-based strategies involving use of catalysts, green solvents, atom economic reactions etc. play a key role because of their exceptional ability to minimize the toxicity or hazards of the side products and processes. With the use of these green techniques, a number of researchers were able to synthesis a wide range of heterocyclic compounds. This chapter highlights the potential and diverse biological activities of saturated sulphur containing heterocyclic compounds including thiirane, thiane, thiolane and many more. The aim of this chapter is to provide fresh perspective on the various techniques employed for the formation of C–S bond by summarizing all green synthesis from 2016 to 2021.
Challenges for machine learning in RNA-protein interaction prediction
Authors: Arora Viplove , Sanguinetti Guido 
Published: January 2022

Abstract
RNA-protein interactions have long being recognised as crucial regulators of gene expression. Recently, the development of scalable experimental techniques to measure these interactions has revolutionised the field, leading to the production of large-scale datasets which offer both opportunities and challenges for machine learning techniques. In this brief note, we will discuss some of the major stumbling blocks towards the use of machine learning in computational RNA biology, focusing specifically on the problem of predicting RNA-protein interactions from next-generation sequencing data.
Synthesis of a castor oil-based quaternary ammonium surfactant and its application in the modification of attapulgite
Authors: Yan Xiuhua , Xu Wei , Shao Rong , Haddleton David M. 
Published: January 2022

Abstract
Castor oil-based quaternary ammonium surfactant (COQA) was synthesized by an ester-exchange reaction of refined castor oil (CO) (raw material) with N,N-dimethyl ethanol amine followed by quaternization with epichlorohydrin (ECH). Its surface activity and structural features were determined. The critical micelle concentration (CMC) of the surfactant at 25 °C was 1.79 × 10−3 mol/L. The surface tension of an aqueous COQA solution at CMC was 38.19 mN/m. Subsequently, the synthesized COQA was used to modify attapulgite (ATP) by binding it to the surface of ATP. The change in the morphology of the modified-ATP (M-ATP) was attributed to the presence of the COQA bound to the surface of the rod-shaped crystals, although the crystal structure of the silicate did not change. Compared to ATP, the microstructure of the M-ATP was less rigid.
Review on classification, physicochemical properties and applications of microbial surfactants
Authors: Madankar Chandu S. , Meshram Ashwini 
Published: January 2022

Abstract
Biosurfactants are amphiphilic microbial compounds synthesized from plants and micro organisms that have both hydrophilic and hydrophobic zones, which are classified into liquid-liquid, liquid-solid and liquid-gas interfaces. Due to their versatile nature, low toxicity, and high reactivity at extreme temperatures, as well as – extremely important – their good biodegradability and environmental compatibility, biobased surfactants provide approaches for use in many environmental industries. Biosurfactants produced by microorganisms have potential applications in bioremediation as well as in the petroleum, agricultural, food, cosmetics and pharmaceutical industries. In this review article, we include a detailed overview of the knowledge obtained over the years, such as factors influencing bio-surfactant production and developments in the incorporation of biomolecules in different industries and future research needs.
Phase studies of ethyl ammonium nitrate (EAN)/sugar surfactant microemulsions: effect of chain length of alkanes and length of the hydrophobic chain of the non-ionic surfactant
Authors: Solanki Shehnaz H. , Patil Sandeep R. 
Published: January 2022

Abstract
Microemulsions were formulated with the ionic liquid ethylammonium nitrate (EAN) used instead of water as the polar phase, hydrocarbon solvents (n-alkanes) and sugar-based non-ionic surfactants, and their phase behaviour and microstructure were investigated. The sugar-based non-ionic surfactants used are non-toxic, biodegradable and environmentally friendly. Due to these properties, their use in microemulsion systems is a clear alternative to the conventionally used non-ionic surfactants from the class of alkyl polyoxyethylene ethers (C
i
E
j
). The influence of n-alkanes with different chain lengths and of sugar-based nonionic surfactants with hydrophobic chains of different lengths on the microemulsion system was also investigated. The results obtained for the microemulsions with EAN described here are similar to those obtained for microemulsion systems formulated with water as the polar solvent. Liquid crystalline (LC) phases were observed in microemulsion systems with sugar-based nonionic surfactants having longer hydrocarbon chains, at lower temperatures and higher surfactant mass fraction.
Influence of n-alcohols on aqueous DTAB micelles studied by ultrasonic analysis
Authors: Patil Kiran D. , Sonawane Gunavant H. , Borse Mahendra S. 
Published: January 2022

Abstract
The influence of chain length of n-alcohols such as 1-butanol, 1-pentanol, 1-hexanol and 1-heptanol on cationic dodecyl trimethyl ammonium bromide (DTAB) micelles has been investigated. The effect of concentration was determined at alcohol concentrations of (10, 20, 30, 40 and 50) mM and at temperatures of 298.15 K, 303.15 K, 308.15 K and 313.15 K using ultrasonic velocity, density, viscosity and conductivity measurements. To study molecular interactions in micelles of various mixtures of DTAB and n-alcohols by using acoustical parameters, such as adiabatic compres-sibility (β
ad), intermicellar free length (L

f
), acoustic impedance (Z), molar volume (V

M
) have been calculated by using ultrasonic velocity (U) and density (ρ). With the help of the trends observed when varying these parameters, the molecular interactions and thus the micellar growth of mixed systems of DTAB and n–alcohol were discussed. Viscosity data such as absolute viscosity, viscous relaxation time, oil solubilization, foam stability and conductance data complemented the observed ultrasonic data.
Analysis of the second virial coefficient, and application to rare gas mixtures
Authors: Somuncu Elif , Mamedov Bahtiyar A. 
Published: January 2022

Abstract
The second virial coefficients characterize the real-gas non-ideality caused by the interaction between molecular pairs and ensure a link between macroscopic thermodynamic properties and microscopic molecular interactions because they depend on intermolecular interaction energy and temperature. Therefore, the second virial coefficients that are suitable for calculating the thermodynamic properties of gases used in the many fields in this work are preferred. In this study, a semi-analytic representation for the second virial (SV) coefficient over exponent–spline-Morse-spline-van der Waals potential (ESMSV), investigating the thermodynamic properties of rare gases, is presented. In the study the series formulae of the hypergeometric function, exponential function, gamma function, Meijer function, and binomial expansion have used in the suggested method. The numerical approach has been used mostly to evaluate the SV coefficient with ESMSV potential in literature. This unified formula can be applied and tested for rare gases. The obtained results for the SV coefficient over ESMSV potential of 4He–4He, 4He–Ne, 4He–Ar, 4He–Kr, 4He–Xe, Ne–Ne, O2–O2, and Ar–O2 rare gases have been compared with alternative experimental data and numerical calculations and shown that semi-analytical expression can be successfully applied to evaluate simple fluids.
Ternary rare-earth hydride oxides: stability in air and potential use as precursors for the synthesis of materials
Authors: Zapp Nicolas , Kohlmann Holger 
Published: January 2022

Abstract
Ternary rare-earth hydride oxides (or oxyhydrides) REHO show rather high thermal stability and inertness in air. SmHO remained intact when stored in air for 12 h, while after storage for one year, it completely hydrolysed to form Sm(OH)3. In contrast, YHO and HoHO show only slight decomposition upon longer storage. The cation’s basicity and the air humidity apparently are crucial factors in the air stability of the compounds. Their reactions with various gases were investigated, in order to better understand factors governing the stability in air and to map their potential as precursors in materials synthesis. Both SmHO and YHO reduce CO2 to carbon and form the metastable C-type rare-earth sesquioxides RE
2O3 instead of the thermodynamically stable B-type. YHO reacts with gaseous ammonia to a red powder. By X-ray diffraction, this is identified as yttrium nitride, but the color of the sample suggests it to be an oxygen-poor nitride oxide (oxynitride) phase YN1−x
O
x
. These results underline the potential of rare-earth hydride oxides as precursors for the synthesis of other rare-earth compounds. The stability in air, even at elevated temperatures of some rare-earth hydride oxides such as YHO and HoHO are advantageous for potential applications as functional materials.
Evaluation and enzyme-aided enhancement of anti-photoaging properties of Camellia japonica in UVA-irradiated keratinocytes
Authors: Oh Jung Hwan , Nam Gi Baeg , Karadeniz Fatih , Kong Chang-Suk , Ko Jaeyoung 
Published: January 2022

Abstract
Exposure to ultraviolet (UV) radiation is the main reason behind extrinsic skin aging. Changes due to chronic UV exposure are called photoaging. Natural products are effective ingredients against UV-mediated skin damage. Present study investigated the anti-photoaging properties of Camellia japonica flowers which possess various bioactivities. To enrich the extracts of C. japonica flowers, pectinase and beta-glucosidase treatment was employed. Anti-photoaging effect was screened using the changes in MMP-1 and collagen levels in UVA-irradiated human HaCaT keratinocytes. The crude extract of C. japonica flowers (CE) was shown to decrease the UVA-induced MMP-1 secretion while attenuating the collagen levels. Pectinase and beta-glucosidase treated CE (ECE) showed increased anti-photoaging effects against UVA-induced changes in MMP-1 and collagen production. Camellenodiol (CMD), a known triterpenoid from C. japonica, isolated as the active ingredient of ECE and its anti-photoaging effect was screened. Results showed that CMD ameliorated the UVA-induced deterioration in collagen levels by suppressing MMP-1 production in transcriptional level. CMD treatment downregulated the phosphorylation of p38, ERK, and JNK MAPKs along their downstream effectors, c-Fos, and c-Jun. In conclusion, enzyme-assisted extraction of C. japonica flowers was suggested to enhance the anti-photoaging properties suggestively through high bioactive content such as CMD.
Theoretical Studies of Rare-Earth Nuclei Leading to 50Sn-Daughter Products and the Associated Shell Effects
Authors: Kumar S. 
Published: January 2022

Cluster decays of rare-earth nuclei are studied with regard for neutron magic shells for 50Sn nucleus as a daughter product always. The 100Sn and 132Sn radioactivities are studied to find the most probable cluster decays and the possibility, if any, of new neutron shells. For a wide range of parent nuclei considered here (from Ba to Pt), 12C and 78Ni from the 112Ba and 210Pt parents, respectively, are predicted to be the most probable clusters (minimum decay half-life) referring to100Sn and 132Sn daughters. The 22Mg decay of 122Sm is indicated at the second best possibilty for the 100Sn-daughter decay. In addition to these well-known magic shells (Z = 50, N = 50 and 82), a new magic shell at Z = 50, N = 66 (116Sn daughter) is indicated for the 64Ni decay from the 180Pt parent.
Фізичний механізм набухання кератину
Authors: Булавін Л.А. , Забашта Ю.Ф. , Каспрова А.В. , Сенчуров С.П. , Грабовський Ю.Є. , Алєксєєв С.О. 
Published: January 2022

Досліджено механізм набухання кератину у водному розчині тіогліколевої кислоти. Отримано рентгенівські рефлектограми та ІЧ-спектри, залежність акустичного модуля від статичного напруження для ненабухлого та набухлого кератину. На основі цих експериментальних даних встановлено, що при набуханні кератину молекули тіогліколевої кислоти розташовуються у внутрішньофібрилярних невпорядкованих областях, приводячи до орієнтації спіральних сегментів. При цьому між орієнтованими сегментами виникають нові дисульфідні зв'язки, які фіксують новоутворену структуру.
Screening for Adverse Childhood Experiences in Children: A Systematic Review
Authors: Loveday Sarah , Hall Teresa , Constable Leanne , Paton Kate , Sanci Lena , Goldfeld Sharon , Hiscock Harriet 
Published: January 2022

CONTEXT
Adverse childhood experiences (ACEs) are associated with increased risk of poor mental health outcomes. Although there is interest in screening for ACEs for early identification and intervention, it is not known whether screening improves outcomes for children.

OBJECTIVE
To systematically review whether screening for ACEs in children leads to an increase in (1) identification of ACEs, (2) referrals to services, (3) increased uptake of services, and (4) improved mental health outcomes for children and parents.

DATA SOURCES
Ovid Medline, PsycINFO, CINAHL, and Center for Clinical and Translational Research electronic databases were searched between 2009 and 2021.

STUDY SELECTION
Studies were included if researchers screened for current ACEs in children aged 0 to 12 years and they had a control comparison.

DATA EXTRACTION
Information was extracted, including study characteristics, sample demographics, screening tool characteristics, referral rates to services, uptake rates, and mental health outcomes.

RESULTS
A total of 5816 articles were screened, with 4 articles meeting inclusion criteria. Screening for ACEs increases identification of adversity and may increase referrals to services. There are limited data about whether this leads to an increase in referral uptake by families. There are no reported data addressing mental health outcomes.

LIMITATIONS
There are few published control trials of moderate quality.

CONCLUSIONS
There is limited evidence that screening for ACEs improves identification of childhood adversity and may improve referrals. If we are to realize the hypothesized benefits of ACEs screening on child and parent mental health, it is essential to understand the barriers for families taking up referrals.
Luminescent silica microagglomerates, synthesis, and environmental testing
Authors: Hubbard Lance , Reed Clara , Uhnak Nicolas , Sumner Ryan , Cell Trevor , Kinney Erin , Smith Nathaniel , Allen Caleb , Foxe Michael , Carman April 
Published: January 2022

AbstractTracking mass through harsh environments requires surrogate particles that withstand the event and endure until sampling. Silica-covered quantum dots have been shown to withstand a range of environmental pHs from months to years; in this work they are shown to endure in anticipated local environments. Two methods of particle synthesis were employed to produce luminescent silica with particle diameters 0.1–4 μm. These tracer particles scale for mass production, tolerate harsh environments, and endure in debris. They could be deployed in places such as chemical explosions, industrial processes, geologic test beds, oil and gas fields, nuclear reactors, and geothermal plants to track mass under harsh conditions.
Graphical abstract