bluuebunny/crossref_metadata_2025_split huggingface dataset:
Public awareness and attitudes toward biobank and sample donation: A regional Chinese survey
Authors: Gao Zhaolin , Huang Yanxia , Yao Fei , Zhou Ziyu 
Published: November 2022

BackgroundThe biobank is an extraordinary aid to research and scientific progress. Public involvement in biobanks, necessary for their development, is limited due to inadequate knowledge of biobanking and concerns about sample donation. This study explores the effectiveness of different publicity methods in improving participants' willingness to donate, and assesses public motivations and concerns. It aims to identify an efficient method of improving participants' awareness of biobanking and promoting sample donation.MethodsA structured 20-item questionnaire was formulated to evaluate participants' knowledge of and attitudes toward biobanks and sample donation. In total, 1,500 questionnaires were disseminated to three groups of 500 participants who received, respectively, picture-based promotional material, text-based promotional material, or who attended a biobank-related lecture. Of these, 945 completed questionnaires were received. All the participants completed the questionnaires twice, before and after the corresponding publicity education.ResultsAfter each of the three methods of publicity based on text, pictures and a lecture, respondents' willingness to donate samples was significantly increased (P &lt; 0.001), the lecture being more effective than the other two methods (P = 0.001). Participants with a medical background were more willing to donate biospecimens after publicity than those without medical backgrounds (P &lt; 0.005) but had common motivations for donation including altruism and aiding medical research. The main concern hindering respondents' willingness to donate was the security of personal information.ConclusionDifferent types of biobank-related publicity based on text material, pictorial material and a lecture all improved respondents' willingness to donate and reduced concerns regarding sample donation. Medical background was a critical factor affecting attitudes toward sample donation after publicity. The results of this study suggest strategies that may popularize biobanks and enhance sample donation, further promoting the development of biobanks.
Association between nocturnal sleep duration and the risk of hyperuricemia among Chinese government employees: A cross-sectional study
Authors: An Yanni , Li Xuping , Ouyang Feiyun , Xiao Shuiyuan 
Published: November 2022

ObjectivesEvidence has shown that nocturnal sleep duration is associated with the risk of hyperuricemia, yet the findings are inconsistent. Thus, we aimed at exploring the association between nocturnal sleep duration and the risk of hyperuricemia in Chinese government employees.MethodsA total of 10,321 government employees aged 20–60 years were collected from the Cohort Study on Chronic Diseases among Government Employees in Hunan Province, China. Sleep duration was self-reported. And serum uric acid levels &gt;420 μmol/L in men and &gt;360 μmol/L in women were considered hyperuricemia. The association between nocturnal sleep duration and hyperuricemia risk was examined utilizing multivariate logistic regression models. To further examine the connection between nocturnal sleep duration and serum uric acid levels, multiple linear regression analyses were utilized.ResultsThe prevalence of hyperuricemia was 17.2%. The results of logistic regression demonstrated that, in contrast to participants whose sleep duration was 7–8 h, those who slept for &lt;7 h had an elevated risk of hyperuricemia (OR = 1.343, 95%CI: 1.126, 1.601). Further stratified analysis revealed that this association was still observed in those without obesity (OR = 1.365; 95%CI: 1.127, 1.655), hypertension (OR = 1.290, 95%CI: 1.054, 1.578), or diabetes mellitus (OR = 1.361, 95%CI: 1.136, 1.631). Multiple linear regression showed that shorter sleep duration (&lt; 7 h) was positively correlated with serum uric acid levels. In comparison to individuals who slept for 7–8 h, those with sleep duration of fewer than 7 h had serum uric acid levels that were 7.231 μmol/L (95% CI: 2.875, 11.588) higher.ConclusionShort nocturnal sleep duration (&lt; 7 h) was associated with a higher risk of hyperuricemia, especially in participants without obesity, hypertension, or diabetes mellitus. Besides, short nocturnal sleep duration was related to greater uric acid levels.
A 3-year retrospective study of unintended pregnancy in a developed multi-ethnic Asian community: A call for better healthcare system for family planning
Authors: Quak Xin En Stephanie , Sultana Rehena , Aau Wai Keong , Goh Chin Chin , Tan Ngiap Chuan 
Published: November 2022

BackgroundWomen of childbearing age may face unintended pregnancy (UP). They are usually referred by primary care professionals (PCPs) to gynecologists to manage their UP in countries where abortion is legalized. The study aimed to determine the prevalence, demographic profiles, and associated factors of women in a developed community seeking referrals from PCPs for their UP.MethodsThe sociodemographic and clinical data were extracted from the electronic medical records of pregnant multi-ethnic Asian women at eight Singapore public primary care clinics from July 2017 to June 2020. Their demographic profiles were reviewed and compared among women of different age bands using appropriate statistical tests. Logistic regression was used to identify the factors associated with UP referrals.ResultsAmong 9,794 gravid women, 974 of them requested gynecologist referrals to terminate UP over the 3-year period, constituting a prevalence of 9.94%. The mean age of women requesting such referrals was 29.7 ± 7 years. There were 10.7% with more than one prior unintended pregnancy and 15.7% were foreigners. The majority of these women were married, neither required social assistance nor had comorbidities. Only 2.9% of them were known to be prescribed contraceptives. A multivariable logistic regression analysis showed that women of Indian ethnicity, single, aged below 20 years and above 40 years, were more likely to request referrals for UP.ConclusionOne in 10 gravid women had sought referrals for UP, especially adolescents and older women, and Indian ethnicity. An accessible community-based healthcare service to educate and counsel women on family planning is urgently needed to reduce the incidence of UP.
Towards an AI-based understanding of the solar wind: A critical data analysis of ACE data
Authors: Bouriat S. , Vandame P. , Barthélémy M. , Chanussot J. 
Published: November 2022

All artificial intelligence models today require preprocessed and cleaned data to work properly. This crucial step depends on the quality of the data analysis being done. The Space Weather community increased its use of AI in the past few years, but a thorough data analysis addressing all the potential issues is not always performed beforehand. Here is an analysis of a largely used dataset: Level-2 Advanced Composition Explorer’s SWEPAM and MAG measurements from 1998 to 2021 by the ACE Science Center. This work contains guidelines and highlights issues in the ACE data that are likely to be found in other space weather datasets: missing values, inconsistency in distributions, hidden information in statistics, etc. Amongst all specificities of this data, the following can seriously impact the use of algorithms: Histograms are not uniform distributions at all, but sometime Gaussian or Laplacian. Algorithms will be inconsistent in the learning samples as some rare cases will be underrepresented. Gaussian distributions could be overly brought by Gaussian noise from measurements and the signal-to-noise ratio is difficult to estimate. Models will not be reproducible from year to year due to high changes in histograms over time. This high dependence on the solar cycle suggests that one should have at least 11 consecutive years of data to train the algorithm. Rounding of ion temperatures values to different orders of magnitude throughout the data, (probably due to a fixed number of bits on which measurements are coded) will bias the model by wrongly over-representing or under-representing some values. There is an extensive number of missing values (e.g., 41.59% for ion density) that cannot be implemented without pre-processing. Each possible pre-processing is different and subjective depending on one’s underlying objectives A linear model will not be able to accurately model the data. Our linear analysis (e.g., PCA), struggles to explain the data and their relationships. However, non-linear relationships between data seem to exist. Data seem cyclic: we witness the apparition of the solar cycle and the synodic rotation period of the Sun when looking at autocorrelations.Some suggestions are given to address the issues described to enable usage of the dataset despite these challenges.
3D-printed guides for cervical pedicle screw placement in primary spine tumor: Case report and technical description
Authors: Marengo Nicola , Di Perna Giuseppe , Baldassarre Bianca Maria , Cofano Fabio , De Marco Raffaele , Zeppa Pietro , Petrone Salvatore , Ajello Marco , Garbossa Diego , Zenga Francesco 
Published: November 2022

IntroductionFor spine surgeons, dealing with unstable cervical spine has been usually challenging, and this becomes more difficult when facing a primary craniovertebral junction tumor. Primary spine tumor surgery should always include column reconstruction in order to guarantee biomechanical stability of the spine, but surgeons should always be aware that instrumentations could create interferences with postoperative radiations. However, although carbon fiber instrumentations have started to be used in thoracolumbar oncology for few years, these options are still not available for cervical spine. In the reported case, the adopted strategy to obtain adequate column reconstruction was based on the idea of reducing the amount of titanium needed for posterior fixation and maximizing the distance between the radiation target and titanium rods.Case report and aimWe present the case of a 53-year-old woman harboring a craniovertebral junction chordoma. A short occipito-C3 construct was selected. Specifically, titanium cervical pedicle screws were placed by using a new technology consisting in patient-tailored and customized 3D-printed guides. The aim of this case report is to determine the feasibility and safety of 3D-printed guides for cervical pedicle screw (CPS) positioning, even in the case of cervical spine tumor.ConclusionCPS could represent a good solution by providing strong biomechanical purchase and tailored 3D-printed guides could increase the safety and the accuracy of this challenging screw placement, even in oncological patients.
Effect of anesthetics on postoperative nausea and vomiting after peripheral vascular surgery in end-stage renal disease patients: A retrospective observational study
Authors: Cho Ho Bum , Park Sun Young , Kim Nayoung , Choi Sang Jin , Song Sanghoon , Yoo Jae Hwa , Kim Mun Gyu , Chung Ji Won 
Published: November 2022

BackgroundPropofol-based total intravenous anesthesia (TIVA) is considered a prophylactic approach to decrease postoperative nausea and vomiting (PONV). Despite general anesthesia commonly being performed in end-stage renal disease (ESRD) patients, PONV in ESRD patients has not been well-described. We investigated PONV in peripheral vascular surgery under general anesthesia in ESRD patients.MethodsTo compare PONV between propofol-based TIVA and anesthesia with volatile anesthetics, we collected retrospective data from patients who underwent peripheral vascular surgery under general anesthesia from July 2018 to April 2020. We performed univariable and multivariable analyses, including factors that could be associated with PONV and those previously shown to affect PONV.ResultA total of 1,699 peripheral vascular surgeries under general anesthesia in ESRD patients were eligible for analysis. Based on the multivariable analysis, TIVA (odds ratio [OR], 0.45; 95% confidence interval [CI], 0.35–0.60; P &lt; 0.001) significantly decreased PONV. Female sex (OR, 1.85; 95% CI, 1.44–2.38; P &lt; 0.001) and anesthetic duration (OR, 1.01; 95% CI, 1.00–1.01; P &lt; 0.001) were associated with increased PONV.ConclusionPropofol-based TIVA is the most influential factor decreasing PONV after peripheral vascular surgery in ESRD patients. Anesthesiologists can apply propofol-based TIVA as an alternative to anesthesia with volatile anesthetics.
The Bovhyaluronidase Azoximer (Longidaza®) Disrupts Candida albicans and Candida albicans-Bacterial Mixed Biofilms and Increases the Efficacy of Antifungals
Authors: Gatina Alina , Trizna Elena , Kolesnikova Alena , Baidamshina Diana , Gorshkova Anna , Drucker Valentin , Bogachev Mikhail , Kayumov Airat 
Published: November 2022

Background and Objectives: Candida albicans causes various diseases ranging from superficial mycoses to life-threatening systemic infections often associated with biofilm formation, including mixed fungal–bacterial consortia. The biofilm matrix protects cells, making Candida extremely resistant to treatment. Here, we show that the bovhyaluronidase azoximer (Longidaza®) in vitro destroys the biofilm formed by either C. albicans alone or mixed with bacteria, this way decreasing the concentrations of antimicrobials required for the pathogen’s eradication. Materials and Methods: Bovhyaluronidase azoximer, Longidaza® was obtained from NPO Petrovax Pharm Ltd., Moscow, Russia as lyophilized powder. The antifungal activity was assessed by microdilution assay and CFUs counting. Antibiofilm activity was evaluated via biofilms staining and scanning electron microscopy. Results: Thus, treatment with Longidaza® reduced the biofilm biomass of nine C. albicans clinical isolates by 30–60%, while mixed biofilms of C. albicans with various bacteria were destroyed by 30–40%. Furthermore, the concentration of fluconazole required to achieve a similar reduction of the residual respiratory activity of detached cell clumps of four C. albicans isolates has been reduced four-fold when combined with Longidaza®. While in the biofilm, two of four isolates became significantly more susceptible to fluconazole in combination with Longidaza®. Conclusion: Taken together, our data indicate that Longidaza® is capable of suppression of tissues and artificial surfaces biofouling by C. albicans biofilms, as well as facilitating drug penetration into the cell clumps, this way decreasing the effective MIC of antifungals.
Microbiome in Male Genital Mucosa (Prepuce, Glans, and Coronal Sulcus): A Systematic Review
Authors: Gonçalves Micael F. M. , Fernandes Ângela Rita , Rodrigues Acácio Gonçalves , Lisboa Carmen 
Published: November 2022

The human body represents a complex and diverse reservoir of microorganisms. Although the human microbiome remains poorly characterized and understood, it should not be underestimated, since recent studies have highlighted its importance in health. This is especially evident when considering microbiota in the male reproductive system, responsible for men’s fertility and sexual behavior. Therefore, the aim of this systematic review is to provide an overview of the microbial communities of the healthy male genital mucosa and its role in disease. This study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The search was limited to the English language and studies published until August 2022 that included culture-independent techniques for microbiome characterization in male genital mucosa. Ten articles were included. The bacterial composition of the male genital mucosa consists of several genera including Prevotella, Finegoldia, Peptoniphilus, Staphylococcus, Corynebacterium, and Anaerococcus, suggesting that the male genital microbiome composition shows similarities with the adjacent anatomical sites and is related with sexual intercourse. Moreover, male circumcision appears to influence the penile microbiome. Despite the lack of knowledge on the male genital mucosa microbiome in disease, it was reported that Staphylococcus warneri and Prevotella bivia were associated with balanoposthitis, whereas Enterobacteriaceae, Prevotella, and Fusobacterium were more abundant in male genital lichen sclerosus. The limited data and paucity of prospective controlled studies highlight the need for additional studies and established criteria for sampling methods and the microbiome assay procedure. Such a consensus would foster the knowledge about the composition of the genital microbiome of healthy males and its role in disease.
SUJEITOS E IDENTIDADES: A CONSAGRAÇÃO DA ESCRITA IDENTITÁRIA E DIALÓGICA
Authors: Rodrigues Coelho Lucas , Andrade Mariano Nazarete 
Published: November 2022

Este trabalho objetiva analisar os temas e algumas produções textuais publicadas na coletânea Lugar de criação em prosas e versos (MARIANO et al, 2020), a fim de deliberar noções acerca da escrita identitária e dialógica. Portanto, trata-se de um trabalho de pesquisa qualitativa e de caráter bibliográfico, em que se ancora em teóricos como Hall (2019), Silva (2014), Woodward (2014) e Fiorin (2020).
REFERÊNCIAS
AUSTIN, J. L. Como hacer cosas con palabras. Barcelona: Paidós, 1998.
BEAUGRANDE, R. de. New foundations for a science of text and discourse: cognition, communication, and the freedom of access to knowledge and society. Norwood: Ablex, 1997.
DERRIDA, J. Limited Inc. Campinas: Papirus, 1991 apud SILVA, T. T. A produção social da identidade e da diferença. In: SILVA, T. T. (org.). Identidade e diferença: a perspectiva dos Estudos Culturais. 15. ed. Petrópolis: Vozes, 2014.
HALL, S. Quem precisa de identidade? In: SILVA, T. T. (org.). Identidade e diferença: a perspectiva dos Estudos Culturais. 15. ed. Petrópolis: Vozes, 2014.
______. A identidade cultural na pós-modernidade. 12. ed. Rio de Janeiro: Lamparina, 2019.
FIORIN, José Luiz. A linguagem humana: do mito à ciência. Linguística, p. 13-46, 2013.
______. Introdução ao pensamento de Bakhtin. 2. ed. São Paulo: Contexto, 2020.
KOCH, I. V; TRAVAGLIA, L. C. A coerência textual. 18. ed. São Paulo: Contexto, 2018.
MARCUSCHI, L. A. Produção textual, análise de gêneros e compreensão. São Paulo: Parábola, 2008.
MARIANO, N.; PANTA, F.; COELHO, L.; ALVES, A.; SEGUNDO, M. (orgs.). Lugar de criação em versos e prosa. 1.ed. Petrolina: Oxente, 2020.
SANTOS, C. Prefácio. In: MARIANO, N.; PANTA, F.; COELHO, L.; ALVES, A.; SEGUNDO, M. (orgs.). Lugar de criação em versos e prosa. Petrolina: Oxente, 2020.
SILVA, T. T. A produção social da identidade e da diferença. In: SILVA, T. T. (org.). Identidade e diferença: a perspectiva dos Estudos Culturais. 15. ed. Petrópolis: Vozes, 2014.
WOODWARD, K. Identidade e diferença: uma introdução teórica e conceitual. In: SILVA, T. T. (org.). Identidade e diferença: a perspectiva dos Estudos Culturais. 15. ed. Petrópolis: Vozes, 2014.
ESCRITURA É UM GESTO DE CURADORIA
Authors: T. Kurz Giovani 
Published: November 2022

Esboçando novas formas a partir das quais seja possível sistematizar os modos de autoria contemporâneos, este ensaio se dirige às perspectivas canônicas dos estudos sobre a escritura — com R. Barthes, M. Foucault e G. Agamben — de modo a buscar uma aproximação com os debates recentes sobre a curadoria — com O. Oguibe, C. Bishop e F. Pequeno. Desta aproximação, extrai-se a proposição de uma função-curador. Busca-se abrigar, sob esta reflexão, formas dissidentes, ou mesmo dissonantes, de se escrever.
REFERÊNCIAS
AGAMBEN, Giorgio. O autor como gesto. In: _____. Profanações. Tradução Selvino J. Assmann. São Paulo: Boitempo, 2007.
_____. Notas sobre o gesto. In: _____. Notas sobre a política. Tradução Davi Pessoa. Belo Horizonte: Autêntica, 2017.
BARTHES, Roland. A morte do autor. In: ______. O rumor da língua. Tradução Mario Laranjeira. São Paulo: WWF Matins Fontes, 2012.
______. Aula. Tradução Leyla Perrone-Moisés. São Paulo: Cultrix, 2013.
BENJAMIN, Walter. O colecionador. In: ______. Passagens. Tradução Cleonice Paes Barreto Mourão e Irene Aron. Belo Horizonte: UFMG; São Paulo: Imprensa Oficial, 2009.
BISHOP, C. O que é um curador? A ascensão (e queda?) do curador auteur. Revista Concinnitas, v. 02, p. 13, 2015.
FOUCAULT, Michel. O que é um autor? In: ______. Ditos e escritos: estética – literatura e pintura, música e cinema (v. III). Rio de Janeiro: Forense Universitária, 2001.
______. A ordem do discurso. Tradução Laura Fraga de Almeida Sampaio. São Paulo: Loyola, 2014.
GUSMÃO, Manoel. Anonimato ou alterização. Revista Semear. Disponível em http://www.letras.puc-rio.br/unidades&nucleos/catedra/revista/4Sem_18.html. Acesso em: 09 set. 2021.
OGUIBE, O. O fardo da curadoria. Revista Concinnitas, v. 1, n. 6, p. 6-18, 2004.
PEQUENO, F. Curadoria: ensaios & experiências. Revista Concinnitas, v. 02, p. 21, 2012.
RANCIÈRE, Jacques. O dissenso. In: NOVAES, Adauto (org.). A crise da razão. Rio de Janeiro: Fundação Nacional da Arte, 1996.
L'épizootie de myxomatose en France chez le lapin de garenne (oryctolagus cuniculus l.)
Authors: Giban J. , Barthelemy J. , Aubry J. 
Published: November 2022

Les auteurs présentent quelques-unes des conclusions d’une enquête menée auprès des chasseurs sur l’épizootie de Myxomatose en France.
L’historique de l’extension de la maladie est résumé en cinq cartes donnant la progression de la maladie entre juin 1952 et maintenant. La critique de la méthode de présentation est faite. Le printemps et l’été 1953, ainsi que, à un moindre degré, l’existence de foyers secondaires dans le Midi de la France, apparaissent avoir joué un rôle important dans l’extension de la maladie.
Cinq régions de France restent encore peu ou pas touchées par la Myxomatose : Lorraine et Jura, Alpes, Pyrénées, Massif Central et Bretagne.
L’examen des diverses explications de ce fait montre que les facteurs écologiques : densité de population, altitude, présence ou absence de terriers, etc., ont joué un rôle important dans l’extension de la Myxomatose en France.
L’étude des facteurs écologiques mériterait d’être approfondie.
Répercussion de la myxomatose sur les populations de lapin de garenne en France
Authors: Giban J. 
Published: November 2022

This report gives the results of a survey on the present population level of rabbits in Prance after the recent spread of Myxomatosis.
250 «tableaux de chasse» (number of rabbits shot and destroyed during the shooting period) are recorded and analysed. In Sologne, where the rabbits have always been very abundant and, in the district of «Chartres» (département d’Eure-et-Loir) where Myxomatosis was first introduced, the population was exterminated or reduced to a very low level during the first two years after the spread of the disease ; but it increased during the following two years, reaching now from 2 to 25 per cent of the population level before Myxomatosis.
In some places, especially in the habitats where the rabbits were not abundant, the population level may be notably higher. Some data from other districts in France confirm these preliminary results.
At the present time it is therefore very difficult to forecast the future population level of rabbits in France.