bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autocorrelación espacial - Índices para determinar su presencia en datos geográficos: Breve revisión de la literatura
Authors: Bravo López Paul Esteban 
Published: June 2022

La importancia del espacio radica en que todos los eventos que ocurren en nuestro planeta están ligados a una ubicación, no solo espacial sino también temporal; es decir, todo ocurre en algún lugar y en algún momento dado. Ante esto, es necesario identificar las propiedades relevantes de estos eventos. Estas propiedades se relacionan tanto con objetos del mundo real como con las relaciones espaciales entre ellos. En el contexto del análisis de datos espaciales, la dependencia espacial en los valores de los atributos se considera como una propiedad fundamental que se determina por la autocorrelación espacial, que ha sido estudiada por varios autores, quienes han brindado diferentes definiciones de esta; sin embargo se puede decir que la autocorrelación espacial permite analizar la variabilidad de un fenómeno en el espacio para determinar patrones y verificar su comportamiento. Cuando la autocorrelación espacial es fuerte, los valores cercanos de una variable están estrechamente relacionados entre sí; pero cuando es débil, o incluso inexistente, los valores de una variable se distribuyen aleatoriamente en el espacio. Existen varios índices formales que miden la autocorrelación espacial a nivel local o global, los cuales son aplicados en diversos ámbitos de estudio y que se describen en esta breve revisión de literatura.
Palabras clave: Autocorrelación espacial, índices, análisis espacial, información geográfica.
AbstractImportance of space lies in the fact that all events that occur on our planet are linked not only to a spatial but also to a temporal location, i.e. everything happens somewhere and at some point, in time. In view of this, it is necessary to identify the relevant properties of these events. These properties relate both to real-world objects and to spatial relationships between them. In context of spatial data analysis, spatial dependence in attribute values is considered as a fundamental property determined by spatial autocorrelation that has been studied by several authors, who have provided diferent defnitions of it, however, spatial autocorrelation makes it possible to analyze the variability of a phenomenon in space in order to determine patterns and verify its behavior.When spatial autocorrelation is strong, nearby values of a variable are closely related to each other; but when it is weak, or even nonexistent, the values of a variable are randomly distributed in space.There are several formal indices that measure spatial autocorrelation at local or global level, which are applied in various felds of study and are described in this paper.
Keywords: Spatial autocorrelation, indices, spatial analysis, geographic information.
Digital Marketing Sebagai Strategi Pemasaran Kopi Pada Bumnag Nagari Lasi
Authors: Arsyah Ulya Ilhami , Pratiwi Mutiana , Arsyah Rahmatul Husna 
Published: June 2022

Abstract: Industrial era 4.0 brought changes in the economic field, and the consequence of this era was the birth of the digitization process in all fields. Digital marketing for business players is a very important part, even for BUMNAG Nagari Lasi. To support and advance the business, BUMNAG must be able to compete with the competition in the supply of quality products, so the necessary marketing strategy is capable of increasing sales and market expansion, the only one with digital marketing. BUMNAG managers are expected to have a desire to use digital devices, especially when presenting the products they sell. BUMNAG's ability to manage marketing through digital media will make it easier for the products to be known by many people and in demand. However, there are still many BUMNAGs that do not use digital marketing media as a marketing strategy, which makes BUMNAG unable to compete with other SMEs that have used this medium. Therefore, it was considered necessary to implement the activity to carry out training in digital marketing in the advancement of the Kopi Lasi BUMNAG Nagari Lasi.Keywords: digital marketing; marketing strategy; bumnag; lasi coffee Abstrak: Era industri 4.0 membawa perubahan di bidang ekonomi, dimana konsekuensi dari era ini adalah proses digitalisasi di segala bidang. Pemasaran digital bagi pelaku usaha menjadi bagian yang sangat penting, termasuk bagi Badan Usaha Milik Nagari Lasi (BUMNag). Untuk mendukung dan memajukan bisnis, BUMNag harus mampu bersaing dengan kompetitor dalam menyediakan produk yang berkualitas, sehingga diperlukan strategi pemasaran yang mampu meningkatkan penjualan dan perluasan pasar, salah satunya adalah digital marketing. Pengelola BUMNag diharapkan memiliki keterampilan dalam menggunakan perangkat digital terutama dalam memperkenalkan produk yang mereka jual. Kemampuan BUMNag dalam mengelola pemasaran melalui media digital akan memudahkan produk untuk dikenal banyak orang dan diminati. Namun masih banyak BUMNag yang tidak menggunakan media digital marketing sebagai strategi pemasaran sehingga BUMNag kalah bersaing dengan pelaku UKM lainnya yang telah menggunakan media ini. Pengabdian ini dilakukan dengan menggunakan metode studi pustaka, pelaksanaan kegiatan dan evaluasi. Dimana implementasinya dilakukan secara bertahap seperti sosialisasi, pendataan, pembuatan sistem informasi digital marketing dan juga pelatihan admin. Oleh karena itu pelaksanaan kegiatan pengabdian ini sangat dibutuhkan dalam meningkatkan perekonomian masyarakat sekitar melalui pemasaran Kopi Lasi di BUMNag Nagari Lasi.Kata kunci: digital marketing; strategi pemasaran; bumnag; kopi lasi
Optimalisasi Teknologi Pakan Lokal Dengan Pengolahan Jerami Jagung Di Desa Klambir Lima Kebun
Authors: Sari Dini Julia , Setyaningrum Sri , Warisman Warisman 
Published: June 2022

Abstract : Klambir Lima Kebun Village has excellent potential in the form of availability of agricultural land and livestock, as a center for beef cattle development, large amounts of agricultural waste such as corn straw and the majority of the community work as plantation employees, farming and raising livestock. The abundant corn straw in the village of Klambir Lima Kebun can be stored and used when there is a shortage of green fodder, such as a long dry season. To maintain the stability of animal feed, it is necessary to optimize local feed technology by processing fermented corn straw and silage which aims to determine the potential of fermented corn straw and silage which can be used as ruminant animal feed and to determine the capacity of livestock from the potential of fermented corn straw and silage in village of Klambir lima Kebun, Hamparan Perak, Deli Serdang. The implementation method used in this community service is a training method which will then be followed by discussions and hands-on practice on the manufacture of fermented corn straw and silage as well as direct feeding of fermented corn straw and silage to livestock. The results of the activity show that the village of Klambir Lima Kebun has the potential to produce ruminant feed based on local agricultural waste, namely corn straw.Keywords: corn straw; fermentation; silage; feed; livestock Abstrak : Desa Klambir Lima Kebun memiliki potensi unggulan berupa tersedianya lahan pertanian dan peternakan, sebagai sentra pengembangan ternak sapi potong, banyaknya limbah pertanian contohnya jerami jagung dan mayoritas masyarakat bekerja sebagai karyawan perkebunan, bertani dan beternak. Jerami jagung yang melimpah di desa Klambir Lima Kebun dapat disimpan kemudian digunakan pada saat kekurangan pakan penghijauan seperti musim kemarau panjang. Untuk menjaga kestabilan pakan ternak dibutukan optimalisasi teknologi pakan lokal dengan pengolahan jerami jagung fermentasi dan silase yang bertujuan untuk mengetahui potensi dari jerami jagung fermentasi dan silase yang dapat dimanfaatkan sebagai pakan ternak ruminasia dan mengetahui kapasitas tampung ternak dari potensi jerami jagung fermentasi dan silase di desa Klambir lima Kebun, Hamparan Perak, Deli Serdang. Metode pelaksanaan yang digunakan dalam pengabdian masyarakat ini adalah metode pelatihan yang selanjutnya akan dilanjutkan dengan diskusi serta praktek langsung tentang pembuatan jerami jagung fermentasi dan silase serta pemberian langsung jerami jagung fermentasi dan silase pada ternak. Hasil kegiatan diketahui bahwa desa Klambir Lima Kebun sangat berpotensi menghasilkan pakan ternak ruminansia berbasis limbah lokal pertanianya yaitu jerami jagung.Kata kunci: fermentasi; jerami jagung; pakan; silase; ternak.
Chinchilla, M. La gestión del Museo del Prado desde su experiencia más reciente
Authors: Mosquera Pérez Clara 
Published: June 2022

La publicación digital, ha sido editada por el Museo Nacional del Prado y desde la coordinación científica de Marina Chinchilla, Directora Adjunta de Administración del Museo. La obra se ha planteado desde la experiencia particular del Museo Nacional del Prado con la vocación de ser un sustrato metodológico de referencia que pueda guiar a otras instituciones museísticas. Parte del posicionamiento del Museo en el entendimiento de la labor de la gestión museística desde su sentido más amplio, que articula todas las actividades públicas e internas en las que se organiza el museo, y no entendida exclusivamente desde un plano administrativo. Se pone en valor el propio funcionamiento del museo, como una gran estructura, en la que intervienen múltiples profesionales que realizan un trabajo no siempre visible pero necesario. Para ello, se ilustra la trayectoria del Prado de manera general, así como acercándose a aquellos aspectos más excepcionales, como la preparación de los actos conmemorativos de su bicentenario, o la crisis sanitaria de la COVID-19, que ha tenido un fuerte impacto en todos los museos. Se presenta una secuencia de 30 contribuciones realizadas por profesionales del propio Museo, creando un recorrido a través de los grandes temas que tienen especial importancia en la gestión museística, que, en definitiva, es un aspecto integral e intrínseco de todos los ámbitos del museo.
A incidência da sífilis congênita no município de Itumbiara, Goiás, no período de 2015 a 2020: possíveis impactos da pandemia causada pelo SARS-CoV-2
Authors: Resende Karla Pereira , Rosa Francisca Rafaela Pereira de Amorim Castro , Cunha Iane Andrade Maciel Feldner , Lopes Luciana Fernanda Pereira , Gomes Maria Jacilene de Araújo , Carvalho Polianne Rosalve , Meneses Weder Matheus Garbim , Souza Herbert Cristian de 
Published: June 2022

Introdução: a transmissão vertical da sífilis acontece durante a gestação, por mulher não tratada ou tratada inadequadamente. As consequências para o recém-nascido são graves: prematuridade, natimortalidade e manifestações como surdez, cegueira, deficiência mental, alterações ósseas e até mesmo dentais. Conforme a Organização Mundial de Saúde (OMS), a cada ano, ocorreria aproximadamente 1,5 milhão de casos de sífilis em gestantes. Objetivo: conhecer a incidência da Sífilis no município de Itumbiara (GO) no período de 2015 a 2020 e sua relação com a pandemia de COVID-19, bem como investigar casos e taxa de detecção de sífilis congênita no município de Itumbiara (GO) no período de 2015 a 2020, em relação a idade, sexo, faixa etária da mãe, entre outros e analisar a influência da pandemia na quantidade de casos de sífilis congênita no município de Itumbiara (GO), com dados comparativos de 2015 a 2020. Metodologia: trata-se de um estudo epidemiológico, com abordagem quantitativa, de cunho exploratório e descritivo, com dados retrospectivos calcados na base de dados do Sistema de Informação de Agravos de Notificação (SINAN). Resultados e discussão: Percebe-se que de 279 mulheres diagnosticadas com sífilis, 213 foram gestantes (cerca de 76,3%), o ano com mais diagnósticos foi 2017 (21,6%) e o menor 2018 (9,4%), tendo este menos casos que o primeiro semestre de 2020. A maior taxa de detecção da doença nas grávidas foi em 2016 (31,8). Ademais, no aspecto de tratamento, a maioria dos casos de sífilis gestacional foram tratados com penicilina tanto em todo período de tempo (95,5%) como anualmente. O ano de 2019 foi aquele com menor porcentagem de uso da penicilina (84,6%). Dos 13 casos de sífilis congênita, 8 deles (61,5%) tiveram o acompanhamento de pré-natal durante a gestação, enquanto 5 (38,5%), não. Considerações finais: o estudo realizou um diagnóstico dinâmico sobre a ocorrência de casos de sífilis congênita através relação do número de casos entre o ano de 2015 a 2020. Esses subsídios coletados poderão fornecer explicações sobre o número de casos de sífilis congênita no município, também poderão contribuir para a identificação da realidade epidemiológica do município em relação ao diagnostico, tratamento e prevenção da sífilis congênita.
ANALISIS KESIAPAN PENERAPAN REKAM MEDIS ELEKTRONIK (RME)DI RSUP DR. M. DJAMIL PADANG
Authors: Yoga Vesri , Jaka Bestari , Yanti Mendhel 
Published: June 2022

Introduction: The use of Electronic Medical Records (EMR) can provide great benefits for health services such as basic service facilities and referrals (hospitals). Currently, RSUP dr. M. Djamil plans to implement services with electronic medical records for services efficiency and improve the quality of services provided for patients, and ensure patient safety. Therefore, it is necessary to conduct a readiness assessment before implementing EMR. This will help identify processes and priority scales, as well as help establish operational functions to support the optimization of EMR implementation. Research objectives to analyze the readiness of implementing electronic medical records at RSUP dr. M. Djamil Padang. Methods: The research design used in this research is a case study with a qualitative approach. The research was conducted at the RSUP dr. M. Djamil Padang. The research activity was started from August to October 2020. The informants in this study were selected based on the purposive sampling method. Results: This study shows that organizational culture readiness is quite ready. Knowledge related to the application of EMR has been disseminated to all medical staff and medical support and experience in implementing EMR in the Emergency Room, which was currently running, there were still obstacles, still use manual printouts at the end. Regarding the readiness of governance and leadership, RSUP dr. M. Djamil Padang has a clear vision in implementing EMR. The average informant is optimistic that the change in the manual to electronic medical record system (EMR) can be successfully implemented in RSUP dr. M. Djamil Padang because the EMR can provide benefits for the hospital. The readiness of human resources for medical support is still in a gradual process. For infrastructure readiness, hardware and software can be implemented at RSUP dr. M. Djamil Padang in implementing EMR, although there were still some obstacles, the hospital is optimistic that the implementation of this EMR will run well. Conclusion: EMR implementation readiness still needs to be improved, such as organizational culture readiness, governance and leadership readiness, Human Resources (HR) readiness, and infrastructure readiness.
Electron-Beam Irradiated Recombinant Human Collagen-Phosphorylcholine Corneal Implants Retain Pro-Regeneration Capacity
Authors: Simpson Fiona C. , Islam Mohammed Mirazul , Buznyk Oleksiy , Edin Elle , Groleau Marc , Kozak-Ljunggren Monika , Magrelli Federica M. , AbuSamra Dina B. , Argüeso Pablo , Chodosh James , Liszka Aneta , Fagerholm Per , Griffith May 
Published: June 2022

Sterilization of biodegradable, collagen-based implants is challenging as irradiation sterilization methods can alter their mechanical properties. Electron beam (EB) irradiation is a terminal sterilization method that has been used for biologically-derived implants. Here, recombinant human collagen type III-phosphorylcholine (RHCIII-MPC) hydrogels were irradiated with EB doses of 17, 19, or 21 kGy and their subsequent biocompatibility and ability to promote regeneration in rabbit corneas was evaluated. Unirradiated hydrogels stored in 1% chloroform in phosphate-buffered saline (C-PBS) were the controls. There were no significant differences between irradiated and non-irradiated samples in optical or physical properties (tensile strength, modulus, elasticity), or the ability to support cell growth. However, irradiated implants were more sensitive to high levels of collagenase than unirradiated controls and the C-PBS implants had increased cell growth compared to EB and controls at 72 h. Corneal implants e-beamed at 17 kGy or e-beamed and subsequently frozen (EB-F) to increase shelf-life showed no adverse biological effects of the irradiation. EB, EB-F, and C-PBS implanted corneas all rapidly re-epithelialized but showed mild neovascularization that resolved over 6 months. The regenerated neo-corneas were transparent at 6 months post-operation. In vivo confocal microscopy confirmed normal morphology for the epithelium, stroma, sub-basal nerves and unoperated endothelium. Histology showed that all the regenerated corneas were morphologically similar to the normal. Immunohistochemistry indicated the presence of a differentiated corneal epithelium and functional tear film. In conclusion, the e-beamed corneal implants performed as well as non-irradiated control implants, resulting in fully regenerated neo-corneas with new nerves and without blood vessels or inflammation that may impede vision or corneal function. Therefore, a complete validation study to establish EB irradiation as an effective means for corneal implant sterilization prior to clinical application is necessary as a next step.
NGLY1 Deficiency Zebrafish Model Manifests Abnormalities of the Nervous and Musculoskeletal Systems
Authors: Mesika Aviv , Nadav Golan , Shochat Chen , Kalfon Limor , Jackson Karen , Khalaileh Ayat , Karasik David , Falik-Zaccai Tzipora C. 
Published: June 2022

Background: NGLY1 is an enigmatic enzyme with multiple functions across a wide range of species. In humans, pathogenic genetic variants in NGLY1 are linked to a variable phenotype of global neurological dysfunction, abnormal tear production, and liver disease presenting the rare autosomal recessive disorder N-glycanase deficiency. We have ascertained four NGLY1 deficiency patients who were found to carry a homozygous nonsense variant (c.1294G &gt; T, p.Glu432*) in NGLY1.Methods: We created an ngly1 deficiency zebrafish model and studied the nervous and musculoskeletal (MSK) systems to further characterize the phenotypes and pathophysiology of the disease.Results: Nervous system morphology analysis has shown significant loss of axon fibers in the peripheral nervous system. In addition, we found muscle structure abnormality of the mutant fish. Locomotion behavior analysis has shown hypersensitivity of the larval ngly1(−/−) fish during stress conditions.Conclusion: This first reported NGLY1 deficiency zebrafish model might add to our understanding of NGLY1 role in the development of the nervous and MSK systems. Moreover, it might elucidate the natural history of the disease and be used as a platform for the development of novel therapies.
Intravenous Leiomyomatosis Complicated by Arteriovenous Fistula: Case Series and Literature Review
Authors: Kan Haoxuan , Cao Yang , Chen Yuexin , Zheng Yuehong 
Published: June 2022

BackgroundUterine intravenous leiomyomatosis (IVL), a rare type of uterine leiomyoma, is defined by the intravascular proliferation of a histologically benign smooth muscle cell tumor. Pelvic arteriovenous fistula (AVF) is a rare vascular malformation that is most commonly congenital, post-traumatic, or iatrogenic. The link between leiomyomatosis and AVF has received little attention in the medical literature.ResultsWe provide a case series of seven patients, four of whom were from our center, who had IVL complicated by a pelvic AVF. The symptoms of right heart failure were noted as swelling in the abdomen and two legs as well as a significant amount of ascites. Coil embolization of AVFs may be beneficial in minimizing bleeding during IVL surgery. A review of all accessible literature published on IVLs from 2000 to 2020 was conducted, and data were retrieved from 78 papers totaling 262 cases. Complications and recurrence were associated with pelvic mass excision and intravascular remnant tumor, respectively.ConclusionIntravenous leiomyomatosis combined with AVF aggravates congestion symptoms of surrounding organs. It is worth noting the uncommon combination of AVF and IVL, stressing the importance of a thorough assessment and surgical approach in IVL treatment.
Clinical Validation of the Impact of Branch Stent Extension on Hemodynamics in ISF-TEVAR Involving LSA Reconstruction
Authors: Hu Jiateng , Li Fengshi , Qiu Peng , Wu Xiaoyu , Pu Hongji , Zhao Zhen , Qin Jinbao , Liu Guang , Jin Shanliang , Lu Xinwu , Liu Xiaobing 
Published: June 2022

BackgroundThe study of hemodynamics regarding thoracic endovascular aortic repair (TEVAR) is helpful to improve the surgical efficacy.ObjectiveCorrelations between hemodynamic changes and branch stent extension length and interference factors for branch stent extension length of in situ fenestration TEVAR (ISF-TEVAR) involving the left subclavian artery (LSA) were evaluated.Materials and MethodsThis study retrospectively analyzed 196 patients with Stanford type B aortic dissection who received in situ laser fenestrated thoracic endovascular aortic repair with LSA fenestration from April 2014 to March 2021. Branch stent extension to the main stent graft was evaluated by the computed tomographic angiography (CTA). Hemodynamic change of LSA was defined as a 20 mmHg interbrachial systolic pressure difference. The factors affecting the extension of the branch stent were also evaluated.ResultsAll patients underwent ISF-TEVAR with LSA fenestration, and there was no recurrence during the follow-up. The mean length of the branch stent extension was 10.37 ± 0.34 mm, which was used to divide the patients into long and short groups. Asymptomatic hemodynamic changes (defined as a 20 mmHg interbrachial systolic pressure difference) in LSA were observed in 61 patients undergoing ISF-TEVAR involving LSA fenestration. The Spearman correlation analysis showed extension length of a branch stent &gt;1.5 cm elevated the risk of hemodynamic changes.ConclusionOverall, we conclude that branch stent extension length &gt;1.5 cm induced LSA hemodynamic changes. Appropriate shortening of the stent extension length can improve the curative effect of ISF-TEVAR, especially when faced with a type II/III aortic arch and stent angles of &lt;30 degrees.