bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cortical Spectral Dynamics of Vibrotactile Frequency Processing
Authors: Rustamov Nabi , Demarest Phillip , Han Zhuangyu , Mohamud Safia , Haroutounian Simon , Leuthardt Eric C. 
Published: February 2025

Abstract

While scientific research has extensively explored how the brain integrates touch and pain signals, the cerebral processing of specific vibrotactile frequencies remains poorly understood. This gap is particularly significant given clinical evidence that vibrotactile stimulation can reduce pain in both chronic pain patients and experimental settings. Our study investigated the cortical electrophysiological correlates of peripheral vibrotactile stimulation across different frequencies in healthy volunteers, with a focus on frequency-dependent patterns of neuronal activation. While electroencephalogram (EEG) was recorded, healthy participants received vibrotactile stimulation to the left index fingertip at frequencies corresponding to established neural rhythms: delta (2 Hz), theta (6 Hz), alpha (12 Hz), beta (20 Hz), and gamma (40 Hz). We compared the EEG bandwidth activity between vibrotactile stimulation conditions relative to resting baseline. Our findings demonstrated that vibrotactile stimulation produces distinct frequency-dependent patterns of cortical activation. A key finding was that 6 Hz stimulation selectively enhanced theta power in the left prefrontal cortex - an electrophysiological signature previously linked to successful pain relief. These findings advance the understanding of the "spectrotopic" nature of vibrotactile frequency processing in the cortex and provide a mechanistic foundation for developing novel vibration-based therapies in the future.
Study on growth law of austenite grain of by cellular automaton and real-time observation in a high-strength weathering steel
Authors: Cheng Jian , Li Juan 
Published: February 2025

Abstract

This research investigates the development law of austenite grains in a novel V-N microalloyed high-strength weathering steel by cellular automaton and experimental methods. The cellular automaton was employed to mimic the grain transformation of three types of single and smaller grains during austenite grain development.The austenite grains are quadrilateral, hexagonal, or octagonal, each surrounded by a limited number of adjacent grains. The results indicate that during austenite grain development, grains with a boundary number exceeding six continue to expand, approaching a boundary number of six, whereas grains with a boundary number below six progressively decline until they vanish. The austenite grain development process in weathering steel was seen in situ using confocal laser scanning microscopy (CLSM).The CLSM results confirmed the development law of austenite grain as simulated by cellular automata. The used model possesses a superior physical foundation for modeling the advancement of austenite grain development.
Laccase-encapsulated metal-organic frameworks (Lac@MOF): Removal of BPA, a major endocrine disruptor, from the aquatic environment
Authors: ARABACI Gökmen , ÇAĞAN Aleyna , DOĞAÇ Yasemin İSPİRLİ 
Published: February 2025

Abstract

Bisphenol A (BPA) is an endocrine disruptor. The utilization of enzymes in the bioremediation of these compounds offers advantages such as high catalytic efficiency, non-toxicity, high substrate specificity, and short reaction times. However, the use of enzymes in their soluble forms limits their practical applications and presents certain disadvantages, including sensitivity to denaturing agents, non-reusability, and low stability. To address these limitations, enzyme immobilization is a significant method. Recently, porous and large-surface-area metal-organic frameworks (MOFs) have been considered potential candidates for enzyme immobilization. In this study, BPA removal was achieved using an enzymatic process. Encapsulation of laccase was accomplished for the first time during the synthesis of Co2+-and malonic acid-based MOF structures. Optimization and structural characterization (SEM and TGA) of laccase-encapsulated MOF structures (Lac@MOF) were conducted. The enzymatic properties, including temperature, pH, reusability, and kinetic properties of Lac@MOF structures synthesized under optimal conditions, were investigated. The catalytic performance of the laccases increased subsequent to immobilization. The temperature profile at which it exhibited activity broadened and demonstrated enhanced activity in the alkaline range. Notably, the thermal stability results indicated that the activity of the Lac@MOF structures increased by 147% at 60°C, 157% at 70°C, and 134% at 80°C compared to the free enzyme. After the 7th use, 60% of immobilized laccase activity was retained. For BPA, 66% removal was achieved after 230 min.
Enhanced Vehicle Detection in SAR Images via Global and Dual Attention Mechanisms
Authors: LEI Shengjie , WEI Zhiyong , ZHANG Yulian , FANG Meihua , WU Baowen 
Published: February 2025

Abstract

Target detection in Synthetic Aperture Radar (SAR) images is widely applied in various fields, such as geographic information systems, environmental monitoring, disaster warning, urban planning, and military surveillance. Despite the advances in mainstream detection methods, challenges persist in handling complex backgrounds, small targets, and targets with arbitrary orientations. To address these issues, we propose the Global and Dual Attention Network (GDAN), which builds upon the YOLOv5 framework. GDAN incorporates the Spatial Pyramid Pooling Feature Concatenation and Spatial Pyramid Convolution (SPPFCSPC) module to process input images of various sizes and extract multi-level features. The Global Attention Mechanism (GAM) is designed to handle feature interactions in three dimensions simultaneously, enabling adaptive feature aggregation and improving the model's robustness. Furthermore, the Dual Attention (DA) module enables the model to receive multiple feature information from different spatial locations and adaptively acquire global image features. Experimental results demonstrate that GDAN achieves state-of-the-art performance with a mean Average Precision (mAP) of 82.63% on the HighSAR dataset and 91.5% on the VOC dataset, significantly outperforming existing methods. The links to the code https://github.com/ynlsj/Global-and-Dual-Attention-Mechanisms/, dataset(https://github.com/whu-csl/SAR_vehicle_detection_dataset and http://host.robots.ox.ac.uk/pascal/VOC/voc2012/ )
Recent Accomplishments in Exhaled Breath Condensate Analysis - Molecular Aspects
Authors: Silkin Sergey V. , Pekov Stanislav I. , Bocharov Konstantin V. , Popov Igor A. 
Published: February 2025

Abstract:
Nowadays, the research of exhaled breath condensate (EBC) analysis is
widely discussed in the scientific community. The growing interest in EBC analysis
results is related to the ample advantages of non-invasive techniques in healthcare
and related fields. In particular, EBC analysis can be used to diagnose respiratory
diseases, monitor the disease’s course during therapy, and monitor drug intake and
metabolism. This review aims to systematize the accumulated knowledge on EBC
collection, concentration, storage, and analysis methods and compare them with
similar procedures for exhaled breath (EB). We proposed a generalized chemical
classification of EBC compounds that are biomarkers for various diseases. The
potential transformation of substances during EB condensation was considered, and
EBC analysis methods were systematically categorized based on this classification.
Methods for EBC analysis using chromatographic separation with mass spectrometric
detection (hyphenated methods) were separately discussed as the most promising
methods for future research applications.
Enhanced Electrochemical Performance Using Polyaniline/BiPr Composite Nanosheet-modified Glassy Carbon Electrode
Authors: Cai Zhengyu , Chang Yuetong , Pei Mengyan , Huang Jianfeng , Pei Lizhai 
Published: February 2025

Background:
L-cysteine (L-CySH) plays a crucial physiological role in the life-support
system, which has been widely applied in the food and medicine industries. Abnormal content of LCySH
in the human body can lead to liver damage, Alzheimer's disease, and even cancer. Therefore,
it is of great practical importance to investigate highly sensitive and selective methods for the determination
of L-CySH.

Methods:
L-CySH electrochemical detection by cyclic voltammetry (CV) technique was reported
using the polyaniline/BiPr composite nanosheet-modified glassy carbon electrode (GCE).

objective:
Polyaniline/BiPr composite nanosheets modified glassy carbon electrode (GCE) was used for L-cysteine (L-CySH) electrochemical detection by cyclic voltammetry (CV) technique.

Results:
The obtained nanosheets with a size of less than 500 nm were composed of rhombohedral
Bi1.35Pr0.65O3, tetragonal Bi2O3, and hexagonal Pr2O3. Irregular polyaniline nanoparticles were covered
on BiPr nanosheets. Polyaniline/BiPr composite nanosheet-modified GCE had good electrocatalytic
performance for L-CySH detection. A pair of CV peaks was observed on the BiPr composite
nanosheet-modified GCE with the potentials at +0.06 V and –0.75 V. Peak potentials at the polyaniline/
BiPr composite nanosheet-modified GCE were shifted to –0.09 V and –0.72 V. The linear
range detection limit indicated 0.0005–2 mM and 0.086 μM for the polyaniline/BiPr composite
nanosheet-modified GCE.

Conclusion:
Polyaniline/BiPr composite nanosheets provide a kind of new electrode material for
improving the electrochemical performance towards L-CySH determination.
Optimizing Gold Nanoparticle Size and Aggregation Strategies for Enhanced Sers: A Comprehensive Review
Authors: Zulhanip Aida Zulia , Mohamad Hadis Nor Shahanim , Mohd Radzol Afaf Rozan , Rosli Anis Diyana 
Published: February 2025

Abstract:
Surface-enhanced Raman scattering (SERS) is an ultrasensitive spectroscopy technique
that leverages localized surface plasmon resonance (LSPR) in nanostructured metallic substrates.
Its ability to detect and analyze molecules at very low concentrations is certain; however, the effectiveness
is highly dependent on the size and aggregation state of the nanoparticles used as a substrate.
This study analyzes the correlation between key sensitivity parameters consisting of enhancement
factor (EF) and limit of detection (LOD) in relation to the enhanced SERS. The effects of
sensitivity associated with suitably sized nanoparticles focusing on gold nanoparticles (AuNPs)
and their implementation of SERS are comprehensively analyzed. The method for controlling
nanoparticle aggregation is also reviewed as a complementary strategy to enhance SERS performance
alongside the optimal size. The findings indicate that the AuNPs with sizes below 55 nm
provide higher EF and lower LOD due to the increased strength of the electromagnetic field, although
they may suffer from aggregation instability compared to the larger nanoparticles. To manage
this concern, the integrated strategies involving chemical, physical, and self-assembly techniques
of controlled aggregation of AuNPs have a significant impact on forming SERS hot spots
and amplifying signals. Therefore, an adaptation of the approaches to obtain the optimal size and
well-distributed aggregation of AuNPs to achieve a reliable SERS substrate in various applications
serves as a decisive factor. This study identifies the current gaps to address the diversity of
accessible sizes of AuNPs, aggregation control, and challenges in evaluating AuNPs and introduces
a future path for achieving a reliable SERS substrate in diverse applications.
Использование электронных образовательных ресурсов в информационной образовательной среде
Authors: Ничагина А.В. 
Published: February 2025

Автор рассматривает основные подходы использования электронных образовательных ресурсов педагогами и студентами в информационной образовательной среде с учетом современных требований, предъявляемых к высшим учебным заведениям в Российской Федерации. Содержание данной статьи является особенно актуальным в связи с возросшей необходимостью обеспечения образовательных программ возможностями дистанционного или смешанного обучения. Автором проведен глубокий анализ терминологического аппарата в рамках заявленной проблематики, а также выделены ключевые аспекты и проблемы, связанные с функционированием систем дистанционного обучения, с предложением возможных путей их решения на основе практического опыта. Кроме того, в работе уточняется понятие информационной образовательной среды и приводится классификация различных видов онлайн-обучения, образовательных порталов и ресурсов, применяемых в российских вузах. Особое внимание автор акцентирует на сравнительном анализе наиболее перспективных (с точки зрения ведущих средств массовой информации) образовательных платформ и технологий электронного обучения, раскрывая их сильные и слабые стороны. Также в статье рассматривается жизненный цикл электронного образовательного ресурса (от планирования до использования) на примере ресурса «Производственная практика», который был применен в ходе педагогической (производственной) практики студентов на территории Российской Федерации. Автором выделены наиболее эффективные формы и методы организации работы студентов на каждом из этапов.
The author considers the main approaches to the use of electronic educational resources by teachers and students in the information educational environment, taking into account modern requirements for higher education institutions in the Russian Federation. The content of this article is especially relevant due to the increased need to provide educational programs with distance or blended learning opportunities. The author has conducted an in-depth analysis of the terminological apparatus of the stated problems, highlighted the key aspects and problems of the functioning of distance learning systems and proposed possible ways to solve them based on practical experience. In addition, the paper clarifies the concept of an information educational environment and provides a classification of various types of online learning, educational portals and resources used in Russian universities. The author focuses special attention on the comparative analysis of the most promising from the point of view of the leading mass media, educational platforms and e-learning technologies, revealing their strengths and weaknesses. The article also examines the life cycle of an electronic educational resource (from planning to use) using the example of the resource «Industrial Practice», which was applied during the pedagogical (industrial) practice of students in the Russian Federation. The author identifies the most effective forms and methods of organizing students' work at each stage.
REALITA BUDAYA PABALIAN DI DESA BUNTU BARANA KECAMATAN CURIO KAB. ENREKANG
Authors: Muhtadiyah Ikrimah Al Muhtadiyah , M. Muzakkir  , Muhammad Yahdi  
Published: February 2025

Artikel ini bertujuan untuk mengetahui nagaimana realita pabalian di desa Buntu Barana kecamatan Curio kabupaten Enrekang. Jenis penelitian ini tergolong kualitatif dengan pendekatan penelitian yang digunakan adalah: fenomenologi, sosiologi dan etnografi. Adapun sumber data dalam penelitian ini yaitu Kepala Desa, Kepala Dusun, tokoh pendidik dan masyarakat di desa Buntu Barana. Selanjutnya metode pengumpulan data yang digunakan adalah observasi, wawancara dan dokumentasi. Lalu Teknik pengolahan dan analisis data dilakukan melalui tiga tahap, yaitu: reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukkan bahwa realita pabalian di desa Buntu Barana dari keenam bentuk pabalian yang sudah disebutkan sebelumnya ada satu bentu pabalian yang partisipannya sudah berkurang yaitu menanam padi disebabkan oleh beberapa faktor yaitu kemajuan teknologi, kemajuan ilmu pengetahuan, saling mengharapkan dan sudah adanya kebun dan tanaman jangka panjang. Implikasi dari penelitian ini adalah memberikan pesan moral kepada masyarakat di desa Buntu Barana kecamatan Curio kabupaten Enrekang bahwa pentingnya budaya pabalian untuk tetap dipertahankan dan dikembangkan, karena di dalamnya terdapat nilai-nilai Pendidikan Islam dan juga karena tolong menolong sangat dibutuhkan sebagai makhluk sosial.
Investigating the potential role of abrasion in the development of toe tip necrosis in beef cattle: an ex vivo study
Authors: Hedayati Nassim , Espinosa Alvaro , Majcher Kadin , Moya Diego , Jelinski Murray D. , Johnston James D. 
Published: February 2025

Abstract

Objective
To compare regional stiffness of the white line (objective 1) and image-based metrics of damage (objective 2) of control claws and claws subjected to an abrasion simulator mimicking animals abrading their claws against a concrete surface commonly found in feedlots.

Methods
Sixteen (n = 16) cadaveric bovine hind limbs were acquired from participating commercial feedlots and separated into different testing groups: lateral claws subjected to an abrasion simulation (n = 8) and control claws manually rasped to the same level of wear found after the abrasion simulation (n = 8). Claws were subjected to indentation testing along the white line to determine regional stiffness (control = 8; abraded = 8) and contrast-enhanced, high-resolution imaging (control = 6; abraded = 6) where mean image intensity was used to characterize damage. Analysis of variance was used to compare regional stiffness and image intensity of the different groups.

Results
Lower stiffness of the white line along the apical region was noted in abraded claws versus control claws (P < .019). Higher mean intensity (a measure of damage) was found in abraded claws versus control claws (P < .026).

Conclusions
Study findings indicate that abraded claws exhibited lower stiffness along the apical region of the white line relative to control claws. Also, analyses of contrast-enhanced, high-resolution imaging data suggested that pathways for foreign material to enter the claw may be present following abrasion.

Clinical Relevance
These findings support the premise that abrasion may be involved in white line separation and toe tip necrosis pathogenesis. Alternative floorings that minimize abrasion may be beneficial for avoiding toe tip necrosis.
Anatomical aspects, technical nuances, and a case series of the resection of the inferior temporal gyrus as a strategy to access the basal surface of the temporal lobe and the lateral incisural space
Authors: Effgen Erica Antunes , Teyssandier Mariano , Giovannini Sebastian Juan Mária , Jiménez Luis Ángel Canache , da Trindade Érico Samuel Gomes Galvão , Leguina Alejandro Benjamin Romero , Lopes Dionisio Figueiredo , Chaddad-Neto Feres 
Published: February 2025

Background
Pathologies of the basal surface of the temporal lobe (TL) and the lateral incisural space (IS) commonly present microsurgical challenges. Since the inferior temporal gyrus (ITG) is part of both the lateral and the basal surfaces, it has a close relationship with the basal surface of the TL and lacks major white matter tracts, reducing the risk of eloquence. This study aims to describe the technique of ITG resection, its applications in four surgical cases, and the relevant anatomical aspects.

Methods
An anatomical review of the TL and the IS was performed. Anatomical pieces fixed using Klingler’s technique and alcohol-fixed, silicone-injected cadaver heads were used to demonstrate landmarks and relationships. The step-by-step surgical technique is described, with four case reports exemplifying its application.

Results
The patients reported no visual field impairments, memory complaints, or neurological complications. The resection of the ITG increases the working space and wider the surgical corridor, allowing access to medial temporal basal structures and the tentorial notch.

Conclusion
The resection of the ITG represents a useful technique to reach the basal surface of the TL and the lateral IS since it avoids excessive retraction of the TL which may cause vessel injury, mainly to the vein of Labbé. Furthermore, it provides relaxation of the vein of Labbé when venous congestion is present. However, more studies are necessary to demonstrate short and long-term outcomes of the resection of the ITG.
Prostate adenocarcinoma dural metastasis mimicking a subacute subdural hematoma
Authors: Rios-Vicil Christian I. , De Jesus Orlando 
Published: February 2025

Background
Patients with malignancies that have a propensity to develop dural metastasis can present a dural infiltration mimicking a subdural hematoma. Dural metastases originating from prostate cancer mimicking a subdural hematoma are rare.

Case Description
The authors describe the case of a 66-year-old man with a history of prostate adenocarcinoma with vertebral metastases who complained of headaches, weakness, anorexia, and dizziness for 1 month. A head computed tomography scan without contrast demonstrated a right pan-hemispheric subdural collection, which was reported to be a subacute subdural hematoma. Due to the patient’s history of prostate carcinoma, brain magnetic resonance imaging (MRI) with and without gadolinium was requested before the surgery, which showed substantial enhancement of the subdural collection, suggesting a tumoral collection. Based on the MRI findings, an open biopsy was performed, revealing extensive bone infiltration and a thickened dura with a large subdural tumoral component suggestive of disseminated pachymeningeal carcinomatosis. No hematoma was identified.

Conclusion
This case report demonstrated how metastatic lesions can mimic subdural hematomas. This disease carries a poor prognosis. Diagnosing and managing this rare entity warrants high suspicion to guide the patient and the family members in decision-making.
A rare case report of primary malignant melanocytoma of foramen magnum and literature review
Authors: Hassan Ahmad , Ahmed Noman , Khalid Shah , Enam S. Ather 
Published: February 2025

Background
Primary malignant melanoma is an extremely rare pathology that can occur anywhere in the brain and spinal cord. Patients often present with symptoms like that of brain tumors. This similarity and inability to make a definitive diagnosis from radiological imaging alone make it a challenging diagnosis. Gross total resection is the accepted mainstay of treatment, while histopathological biopsy can confirm the diagnosis.

Case Description
A young gentleman who was otherwise healthy presented with neck pain and right-sided weakness. Magnetic resonance imaging revealed an extra-axial mass at the level of the foramen magnum. The patient underwent lateral sub-occipital craniotomy with C1 laminectomy and maximum safe resection of the lesion. Intra-operatively, a firm, moderately vascular black-colored dura-based lesion was found. The frozen section revealed highly pigmented spindle cell neoplasm, and histopathology confirmed that it was malignant melanoma. Postoperative recovery was unremarkable.

Conclusion
Primary malignant melanoma is rare and very challenging to diagnose. It demands an early diagnosis and meticulous surgical management for a favorable prognosis.