bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence of Congenital Anomalies of the Coronary Arteries in Embalmed Cadavers
Authors: Cubas Santiago , Garretano M. Alejandra , Vázquez Leticia , Berke Andrés , Olivera Eduardo 
Published: March 2022

Abstract
Introduction: Coronary anomalies, whose incidence is 0.17 to 1.5%, are relevant since they can debut as sudden cardiac death and can determine technical difficulties in interventional procedures such as coronary angiography. This prompted the following study, whose objective is to determine the incidence of anomalies and anatomical variants in the origin and proximal course of the coronary arteries, in a cadaveric population. Materials and methods: 81 hearts were dissected from adult cadavers, of both sexes, previously fixed and preserved in a 10% formaldehyde-based solution. Once the heart was released, the identification and subsequent dissection of the coronary arteries and coronary ostia were carried out. The following data were recorded: number of ostiums, aortic sinus where said ostiums are located, artery that gives origin, route and direction of the same. The data were recorded in tables for later analysis. Results: Of the total of 81 dissected hearts, 45 (55.6%) presented “classic” coronary arteries in origin and proximal path and 36 (44.4%) presented normal anatomical variants and coronary anomalies. Conclusions: Knowledge of coronary anomalies is of the utmost importance, given that between 20% to 90% present with sudden cardiac death and given that when it comes to performing interventional procedures, their ignorance may determine an increase in the duration of the procedures with greater contrast input and radiation exposure for the patient.
Monitoring and prediction of wheat stripe rust based on hyperspectral and meteorological data
Authors: Ma Chunyan , Dong Jinhui , Ding Fan , Li Changchun 
Published: March 2022

Abstract

This study integrated spectral sensitivity values and absorption characteristic parameters based on canopy hyperspectral data and meteorological data, e.g. air volume, average air temperature, relative humidity, sunshine hours, and precipitation. These include the total area of absorption peaks, the area at the left end thereof, absorption depth, and symmetry. This study analyses correlations between these factors and a disease index based on partial least squares method and constructs the small of flag picking period, early and middle grouting period, and the entire growth period. The disease condition inversion model of wheat stripe rust was used to verify the accuracy of the model. The correlation of NDVI, RDVI, TVI, DVI, RVI, and meteorological factors with stripe rust were analysed simultaneously. DVI and average temperature values with a high correlation degree and stripe rust occurrence probability were selected, a prediction model of wheat stripe rust occurrences was established, and the accuracy of the model was verified. Results showed that the average R2 coefficients of the inversion model for the disease index in three growth periods and the entire growth period were 0.94 and 0.92, respectively; the average RMSE values were 0.068 and 0.063, respectively, with high inversion accuracy,which indicated that the prediction model based on spectral data and meteorological data had high prediction accuracy and good prediction effect. It provides new technology and method for monitoring and forecasting crop diseases and insect pests.
Does the relative importance of the OxCAP-MH’s capability items differ according to mental ill-health experience?
Authors: Helter Timea Mariann , Kaltenboeck Alexander , Baumgartner Josef , Soennichsen Andreas , Mayrhofer Franz , Heinze Georg , Wancata Johannes , Simon Judit 
Published: March 2022

Abstract
Background
Some capability dimensions may be more important than others in determining someone’s well-being, and these preferences might be dependent on ill-health experience. This study aimed to explore the relative preference weights of the 16 items of the German language version of the OxCAP-MH (Oxford Capability questionnaire-Mental Health) capability instrument and their differences across cohorts with alternative levels of mental ill-health experience.
Methods
A Best-Worst-Scaling (BWS) survey was conducted in Austria among 1) psychiatric patients (direct mental ill-health experience), 2) (mental) healthcare experts (indirect mental ill-health experience), and 3) primary care patients with no mental ill-health experience. Relative importance scores for each item of the German OxCAP-MH instrument were calculated using Hierarchical Bayes estimation. Rank analysis and multivariable linear regression analysis with robust standard errors were used to explore the relative importance of the OxCAP-MH items across the three cohorts.
Results
The study included 158 participants with complete cases and acceptable fit statistic. The relative importance scores for the full cohort ranged from 0.76 to 15.72. Findings of the BWS experiment indicated that the items Freedom of deciding for yourself and Limitation in daily activities were regarded as the most important for all three cohorts. Freedom of expression was rated significantly less important by psychiatric patients than by the other two cohorts, while Suitable flat situation appeared significantly less important by the expert cohort. There were no further significant differences in the relative preference weights of OxCAP-MH items between the cohorts or according to gender.
Conclusions
Our study indicates significant between-item but limited mental ill-health related heterogeneity in the relative preference weights of the different capability items within the OxCAP-MH. The findings support the future development of preference-based value sets elicited from the general population for comparative economic evaluation purposes.
Development of novel methotrexate-loaded nanocochleates for breast cancer targeting.
Authors: Rajnani Nikhil , Kurup Nalini 
Published: March 2022

Abstract
The objective of this research was to develop stable methotrexate(MTX) loaded nanocochleates (MTX-NC) drug delivery system to achieve controlled drug release,targeted delivery and enhanced anticancer potency with reduced dose and its effect on Breast cancer cell line. The development involved the loading of MTX to nanocochleates (MTX-NC) through conversion of phosphatidyl choline and cholesterol bearing liposome on addition of calcium ions and compared with MTX and MTX-NC. Optimized NC under optimized conditions showed particle size and zeta potential of 298.7nm and -12.9mv respectively, high entrapment efficiency 75%, drug loading of 37.5% and drug content 99%. Investigation on the drug lipid interaction using FTIR confirmed the compatibility of drug with the lipid carrier. SEM and TEM images of NC indicated that the particles were in a rod cylindrical shape with a smooth surface.Formulated MTX-NC demonstrated higher in-vitro anticancer activity in human breast cancer MCF-7 cells. The concentration of the drug needed for growth inhibition of was 47% for free MTX(80µg/ml) while it was -35.6% for the MTX-NC (80µg/ml) . Furthermore, the LC50 value of free MTX and MTX-NC was NE and 75.3µg/ml respectivelty.GI50 value of free MTX and MTX-NC was <10µg/ml. The results indicate that the MTX- NC has the potential to be applied for targeting anticancer drug delivery.
Changes in Adherence to Oral Medications of People With Mental Illness During the Pandemic: Neuroticism and Conscientiousness Personality Traits Moderate the Effect of Medication Beliefs
Authors: Ferretti Fabio , Goracci Arianna , Laurenzi Pier Francesco , Centola Rossella , Crecchi Irene , De Luca Aldo , Monzillo Janette , Guidi Omar , Sinigaglia Giusy , Cuomo Alessandro , Bolognesi Simone , Travagli Valter , Fagiolini Andrea , Coluccia Anna , Pozza Andrea 
Published: March 2022

Abstract
Objectives. After the declaration of pandemic status in several countries, the continuity of face-to-face visits in psychiatric facilities has been delayed, or even interrupted to reduce viral spread. Little is known about the personality factors associated with medication beliefs and adherence amongst individuals with mental illness during COVID-19 pandemic. This longitudinal study explored whether the big-five personality traits prospectively moderate the effects of medication beliefs on changes in adherence during the pandemic for a group of outpatients with psychosis or bipolar disorder. Results. Thirteen outpatients undergoing face-to-face follow-up assessments during the pandemic were included (41 observations overall). Participants had stronger concerns about their psychiatric medications rather than beliefs about their necessity, and adherence to medications was generally low. Participants with higher necessity beliefs had a better adherence to medications than those who perceived less their benefits. People with higher conscientiousness and neuroticism traits and more concerned about the medication side effects had a poorer adherence.These preliminary data suggest the importance of a careful assessment of the adherence to medications amongst people with psychosis/bipolar disorder during the pandemic. Interventions aimed to improve adherence might focus on patients’ medication beliefs and their conscientiousness and neuroticism personality traits.
Bio quantum path duality metamorphosizes Newtonian rigid inertia into topological bio-inertia
Authors: Lai Yi Yu 
Published: March 2022

Abstract
Newtonian inertia has initiated science centuries ago and dictates modern society with isolated logic systems. The hidden premise of this system is rigid existence in an isolated environment that defies any internal motion. Later presented equivalent principle and the T-symmetry reversible processes also follow such a notion. However, bio-inertia originates from the blind spots of this system. (Surface tension inversion as the most universal interaction is sacrificed for methodological isolation/test purposes and then neglected by science.) We define and experiment bio-inertia as “parameter-against-gravity-internal-motion”, revealing inversion time or memory which maintains bio-systems in an entropy-controlled state originates from topological event inversion superposition of bio quantum paths, conventional quantum collapse instancy is then extended to lifespan. Bio quantum path duality physically equivalent inversion time between Planck regions and surface tension regions by a string or surface tension topological property equation drives biological functioning and evolution, which is generalized as the Basic Law of evolution. The topological copy quiddity of life is then unveiled.
High-Intensity Focused Ultrasound or Uterine Artery Embolization combined with ultrasound-guided dilatation and curettage in Cesarean scar pregnancy: a retrospective cohort study
Authors: Gan yanqiong , Zhou Yuqin , Wang Yanlin , Jing Qiao , Zhang Feng , Shi Qi 
Published: March 2022

Abstract
BackgroundCesarean scar pregnancy (CSP) is a rare and new form of ectopic pregnancy. With increasing rate of cesarean delivery worldwide during the decades, the incidence of CSP increases as well. It may cause massive hemorrhage, uterine rupture, placenta percreta, hysterectomy or even maternal death. This study is to compare the efficacy of high-intensity focused ultrasound (HIFU) and uterine artery embolization (UAE) associated with ultrasound-guided dilatation and curettage (UGDC) in three types of CSP. Methods403 CSP patients were treated with UGDC after pretreatment. Among them, 288 patients chose HIFU before UGDC, while the others (n=115) chose UAE. The body mass index (BMI), gravidity, parity, the number of cesarean delivery, the interval of previous cesarean delivery (PCD), the length, thickness and width of uterus and gestational sac, fetal cardiac activity, the types of CSP, the baseline of beta-human chorionic gonadotropin (β-HCG), the value of β-HCG before and 24 hours after pretreatment, hospital expenditure, the value of hemoglobin before and 24 hours after dilatation and curettage (D&C) and severe complications were collected and compared between the two groups. ResultsAll patients were successfully treated without severe complications. There was no significant difference in maternal age, BMI, gravidity, parity, the number of cesarean delivery, the interval of PCD, the volume of uterus and gestational sac, fetal heart activity, types of CSP and baseline serum β-HCG level between the two groups. The median hospital expenditure and blood loss were less in HIFU group and the median decline rate of β-HCG was higher in HIFU group (p=0.000, p=0.000, p=0.006, respectively). 39 (13.54%) patients in HIFU group, while 21 (18.26%) cases in UAE group used Foley balloon to control the vaginal bleeding.ConclusionBoth HIFU and UAE combined with UGDC have high successful rate in the treatment of CSP. While, HIFU followed by UGDC might be better for less hospital expenditure, blood loss and higher decline rate of β-HCG.
Temporal and Spatial Distribution Characteristics of Drought and Flood Considering the Influence of Underlying Surface in Hainan Island, Tropical Areas of China
Authors: Ye Changqing , Zou Yi , He Yanhu , Lin Youwen , Li Dan , Zhu Lirong 
Published: March 2022

Abstract
Most studies of temporal and spatial distribution characteristics for droughts and floods analysis were conducted only from the perspective of a single factor (precipitation), while ignoring the impact of the characteristics of the underlying surface on the formation of droughts and floods. Using the daily precipitation data of 88 meteorological stations in Hainan province from 1970 to 2019, the 30m resolution DEM data and land use dataset, etc, the precipitation Z index is used to evaluate the drought and flood levels in Hainan. The analysis results were revised by underlying surface data to evaluate the spatiotemporal characteristics of the drought and flood area in Hainan. The drought-prone areas and flood prone areas in Hainan Island were divided, and on this basis, the set pair analysis method was used to identify the regions with alternating drought and flood areas in Hainan. The results show that the overall arid area shows an obvious downward trend, while the flood area presents an increasing trend. The drought-prone areas throughout the year are more concentrated in the northeast of Hainan Island, while flood prone areas are mainly distributed in the eastern coastal areas. The regions where drought and flood occur alternately are small but concentrated. The drought and flood prone areas and alternate drought and flood areas before and after the revision by the underlying surface were compared. It can be seen that the overall trend is relatively similar and obvious before and after the revision. The result of drought areas before revision is 7.97 times larger than that after revision. The flood prone areas before revision are 2.91 times larger than that after revision. Finally, combining climate and underlying surface factors, suggestions for drought and flood prevention are put forward.
Influence of small businesses on increasing the innovative potential of sciences
Authors: Барковская В.Е. 
Published: March 2022

В статье обозначен сектор малого бизнеса как инструмент повышения инновационного потенциала наукоградов. Проведен анализ наукоградов в Московской области и состояния малого бизнеса в инновационно-технологическом наукограде Королёв, где отражена доля малого бизнеса в секторах экономики, оборот малых предприятий и их затраты на инновационную деятельность. Сформулированы направления инновационного развития наукоградов и обозначены показатели, которых необходимо достигнуть. По результатам анализа значения малого бизнеса в повышении инновационного потенциала наукоградов, автором предложены: показатели для оценки инновационного потенциала наукоградов, внедрение онлайн-платформы для предпринимателей, меры по упрощению регистрации субъектов малого бизнеса и организация муниципально-частного партнерства, путем взаимодействия малых предприятий и муниципальных органов власти.
The article identifies the small business sector as a tool for increasing the innovative potential of science cities. The analysis of science cities in the Moscow region and the state of small business in the innovation and technological science city of Korolev, which reflects the share of small business in the sectors of the economy, the turnover of small businesses and their costs for innovation. The directions of innovative development of science cities are formulated and indicators that need to be achieved are indicated. Based on the results of the analysis of the importance of small business in increasing the innovative potential of science cities, the author proposed: indicators for assessing the innovative potential of science cities, the introduction of an online platform for entrepreneurs, measures to simplify the registration of small businesses and the organization of municipal-private partnerships through the interaction of small enterprises and municipal authorities.
The use of special economic zones as a tax instrument for spatial development in the context of Industry 4.0
Authors: Косенкова Ю.Ю. 
Published: March 2022

Переход к Индустрии 4.0 предъявляет к органам власти Российской Федерации определенные требования в части стимулирования пространственного развития. В статье рассмотрено использование особых экономических зон в качестве инструмента пространственного развития, а также рассмотрена возможность и целесообразность использования исключительно налоговых методов для достижения поставленной цели.
The transition to Industry 4.0 requires the application of measures to stimulate spatial development. The article discusses the use of special economic zones as a tool for spatial development. In addition, the possibility and feasibility of using exclusively tax methods to achieve this goal is considered.
Assessment of the innovative infrastructure of the external environment of small enterprises and their innovativeness
Authors: Горохова А.Е. , Зайцев И.А. 
Published: March 2022

В статье рассмотрены изменения в инновационной инфраструктуре вокруг малого предприятия, произошедшие в условиях цифровой экономики, как технические, так и образовательно-управленческие. Рассмотрены планы по развитию инновационной инфраструктуры до 2024 года, включающие в себя переход народного хозяйства на новые цифровые стандарты работы, а также совершенствование кадрового состава, обучение цифровой грамотности населения. Проведен анализ взаимосвязи инновационной инфраструктуры и инновационной деятельности малого предприятия, найдены общие моменты, что позволяет выработать стратегию взаимосвязанного развития. Рассмотрены методики оценки инновационной инфраструктуры и инновационной деятельности малого предприятия в условиях цифровой экономики.
The article examines the changes in the innovation infrastructure around a small enterprise that have occurred in the digital economy, both technical and educational and managerial. Plans for the development of innovative infrastructure until 2024 were considered, including a transitional national economy to new digital work standards, as well as improving the staff, teaching digital literacy of the population. The analysis of the relationship between the innovation infrastructure and the innovative activity of a small enterprise is carried out, common points are found, which allows the use of a strategy of interrelated development. Methods for assessing the innovative infrastructure and innovative activities of a small enterprise are considered in the conditions of the russian digital economy.
Comprehensive assessment of the socio-economic development of the region
Authors: Доменко Ю.Ю. 
Published: March 2022

Проводится исследование по оценке социально-экономического развития региона через анализ имеющегося и использующегося потенциала муниципальных образований. Проводимый анализ позволяет определить особенности муниципальных образований и принятия на их территориях соответствующих видов стратегий социально-экономического развития.
A study is being conducted to assess the socio-economic development of the region, through an analysis of the existing and used potential of municipalities. The analysis makes it possible to determine the characteristics of municipalities and the adoption of appropriate types of strategies for socio-economic development on their territories.
Prospects for the use of composite flame-retardant materials for fire-fighting purposes
Authors: Абразумов В.В. , Фролов С.В. , Токарева О.В. 
Published: March 2022

В статье представлен обзор существующих огнезащитных материалов и покрытий для целей противопожарной защиты конструкций и личного состава пожарных формирований. Рассмотрены механизмы действия компонентов огнезащитных покрытий в условиях действия конвективных потоков тепловой энергии. Выполнен обзор современных огнестойких экранов для защиты пожарных при тушении техногенных пожаров. Предложены пути разработки огнестойких материалов для создания защитных укрытий при тушении лесных пожаров в экстремальных условиях.
The article presents an overview of existing fire-retardant materials and coatings for the purposes of fire protection of structures and personnel of fire brigades. The mechanisms of action of the components of flame-retardant coatings under the action of convective heat energy flows are considered. A review of modern fire-resistant screens for the protection of firefighters in extinguishing man-made fires has been carried out. The ways of developing fire-resistant materials for creating protective shelters for extinguishing forest fires are proposed in extreme conditions.
Problems of multiple use of liquid rocket propulsion systems
Authors: Бершадский В.А. 
Published: March 2022

Сформулированы недостатки двигательных установок жидкостных ракет однократного применения для транспортировки на околоземные орбиты и возвращения на Землю необходимых грузов. В результате анализа ряда публикаций в научно-технической литературе установлены проблемы создания и многократного применения жидкостных ракетных двигателей и научно-технические задачи, которые требуют первоочередных решений. Определены основные направления решения задач на концептуальном и оперативном уровнях в части обеспечения надёжной и безопасной полётной эксплуатации двигательных установок многократного применения, их живучести и межполётного обслуживания.
The disadvantages of single-use liquid-propellant rocket propulsion systems for transporting the necessary cargo to near-Earth orbits and returning it to Earth are formulated. As a result of the analysis of a number of publications in the scientific and technical literature, the problems of creating and repeatedly using liquid rocket engines and scientific and technical tasks that require priority solutions are established. The main directions of solving problems at the conceptual and operational levels in terms of ensuring reliable and safe flight operation of multiple-use propulsion systems, their survivability and inter-flight maintenance are determined.
Numerical and expert-oriented method of choosing the parameters of Sun-synchronous orbits for wide-scale monitoring Northern Russia regions
Authors: Степанов Г.Н. 
Published: March 2022

Среди многообразия различных типов орбит выделяется класс солнечно-синхронных (ССО). Традиционно они используются космическими аппаратами дистанционного зондирования Земли (ДЗЗ). В статье приводятся результаты оценки и анализа параметров солнечно-синхронных круговых орбит с целью обеспечения оптимальных режимов освещённости трассы КА, характеристик обзора поверхности Земли, видимости КА с наземных пунктов с учетом требований и ограничений.
Among the variety of orbits, sun synchronous orbit holds a special place. They are traditionally employed by Earth surveying spacecraft. Article covers evaluation results and parameters analysis for circular sun synchronous orbits - to ensure optimal illumination along satellite ground track, Earth surface observational conditions, satellite visibility from ground stations with related requirements and limitations.