bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional maltreatment and neglect impact neural activation upon exclusion in early and mid-adolescence: An event-related fMRI study
Authors: Schulz Charlotte C. , von Klitzing Kai , Deserno Lorenz , Sheridan Margaret A. , Crowley Michael J. , Schoett Margerete J. S. , Hoffmann Ferdinand , Villringer Arno , Vrtička Pascal , White Lars O. 
Published: February 2022

AbstractChild maltreatment gives rise to atypical patterns of social functioning with peers which might be particularly pronounced in early adolescence when peer influence typically peaks. Yet, few neuroimaging studies in adolescents use peer interaction paradigms to parse neural correlates of distinct maltreatment exposures. This fMRI study examines effects of abuse, neglect, and emotional maltreatment (EM) among 98 youth (n = 58 maltreated; n = 40 matched controls) using an event-related Cyberball paradigm affording assessment of both social exclusion and inclusion across early and mid-adolescence (≤13.5 years, n = 50; >13.5 years, n = 48). Younger adolescents showed increased activation to social exclusion versus inclusion in regions implicated in mentalizing (e.g., superior temporal gyrus). Individual exposure-specific analyses suggested that neglect and EM coincided with less reduction of activation to social exclusion relative to inclusion in the dorsal anterior cingulate cortex/pre-supplementary motor area (dACC/pre-SMA) among younger versus older adolescents. Integrative follow-up analyses showed that EM accounted for this dACC/pre-SMA activation pattern over and above other exposures. Moreover, age-independent results within respective exposure groups revealed that greater magnitude of neglect predicted blunted exclusion-related activity in the parahippocampal gyrus, while EM predicted increased activation to social exclusion in the precuneus/posterior cingulate cortex.
Effect of intraoperative theophylline use on acute kidney injury in paediatric cardiac surgery
Authors: Yavuz Yasemin , Isildak Fatma Ukil 
Published: February 2022

AbstractBackground:This study aimed to examine the effects of theophylline use in preventing renal dysfunction in patients undergoing CHD surgery.Methods:A total of 94 patients aged 1–60 months were included in the study. Patients in the theophylline group were enrolled according to a pre-defined protocol for treatment administration, while controls were selected retrospectively from patients without theophylline treatment during the same period – who were matched according to critical baseline characteristics.Results:The incidence of acute kidney injury was similar between the two groups (p = 1.000). Higher urinary output and lower fluid balance were found intraoperatively and also postoperatively in the theophylline group (all, p < 0.050). Postoperative decrease in urinary output and estimated glomerular filtration rate were higher in the theophylline group (p < 0.050). Lower postoperative urea and creatinine levels were shown in theophylline recipients (p < 0.050). Urea levels increased significantly in the non-theophylline group during surgery (p < 0.001), and no significant change was observed in theophylline group (p = 0.136). Postoperative increase in creatinine and lactate levels was demonstrated in theophylline group (p < 0.050), and lactate levels were higher in the non-theophylline group during and after cardiopulmonary bypass (p = 0.010). Multiple linear regression analysis revealed less reduction in estimated glomerular filtration rate with higher age and in the presence of theophylline use (p < 0.050).Conclusion:Although we demonstrated a similar incidence of acute kidney injury in the both groups, we revealed an important decrease in serum creatinine, urea and lactate levels, accompanied by improved estimated glomerular filtration rate, increased urine output and decreased fluid overload, with theophylline treatment, suggesting that renal functions significantly improved with the use of theophylline.
Administrative and Educational Characteristics of Paramedic Programs in the United States
Authors: Ball Matthew T. , Powell Jonathan R. , Collard Lisa , York Doug K. , Panchal Ashish R. 
Published: February 2022

AbstractIntroduction:Paramedics are a vital component of the Emergency Medical Services (EMS) workforce and the United States health care system. The continued provision of high-quality care demands constantly improving education at accredited institutions. To date, only limited characteristics of paramedic education in the United States have been documented and studied in the literature. The objective of this study was to describe the educational infrastructure of accredited paramedic programs in the United States in 2018.Methods:This is a retrospective, cross-sectional evaluation of the 2018 paramedic program annual report from The Committee on Accreditation of Educational Programs for the EMS Professions (CoAEMSP; Rowlett, Texas USA). The dataset includes detailed program metrics. Additionally, questions concerning program characteristics, demographics, and resources were asked as part of the evaluation. Resource availability was assessed via the Resource Assessment Matrix (RAM) with a benchmark of 80%. Included in the analysis are all paramedic programs with students enrolled. Descriptive statistics were calculated (median, [interquartile range/IQR]).Results:A total of 677 programs submitted data (100% response rate). Of these, 626 met inclusion criteria, totaling 17,422 students. Program annual enrollment varied greatly from one to 362 with most programs having small sizes (18 students [IQR 12-30]). Program duration was 12 months [IQR 12-16] with total hours of instruction being approximately 1,174 [IQR 1069-1304], 19% of which were dedicated to clinical experience. Full-time faculty sizes were small (two faculty members [IQR 1-3]) with most programs (80%) having annual operating budgets below USD$500,000. For programs with an annual budget below USD$100,000 (34% of programs), annual enrollment was approximately 14 students [IQR 9-21]. Degrees conferred by programs included certificates (90%), associate degrees (55%), and bachelor’s degree (2%). Simulation access was assessed with nearly all (100%) programs reporting simple task trainers and 84% of programs investing in advanced simulation manikins. Seventy-eight percent of programs met the RAM benchmark.Conclusion:Most paramedic educational programs in the United States have small annual enrollments with low numbers of dedicated faculty and confer certificates and associate degrees. Nearly one-quarter of paramedic educational programs are not adequately resourced. This study is limited by self-reported data to the national accreditation agency. Future work is needed to identify program characteristics that are associated with high performance.
Implementation and preliminary outcomes of cognitive enhancement therapy for serious mental illness in an outpatient mental health program
Authors: Faith Laura A. , Grove Amber , Jarvis Stephen P. , Rempfer Melisa V. 
Published: February 2022

AbstractBackground:Although numerous evidence-based treatments for serious mental illnesses (SMI) exist, the majority are not widely utilized in clinical settings. Cognitive enhancement therapy (CET) has been tested in randomized trials; however, knowledge regarding implementation and outcomes in naturalistic environments is scarce.Aims:The current study is an uncontrolled, observational study describing implementation and pre- to post-outcomes of CETCleveland®, a community-based version of CET in an outpatient mental health program in the United States.Method:We included n = 34 diverse individuals with SMI. Data include qualitative implementation information and participant outcomes, including measures of cognition, symptoms, satisfaction and adherence.Results:Overall, participant satisfaction was positive, and adherence was comparable with previous studies. Implementation information includes training, clinician and setting characteristics, and barriers and solutions. Preliminary outcomes showed that participants significantly improved in areas of neurocognition and symptoms.Conclusions:Overall, our results demonstrated successful early implementation of CET in a diverse, outpatient mental health program and provided preliminary support for the clinical utilization of CET. We hope these results will promote further access to CET and other evidence-based psychiatric rehabilitation programs in community clinics.
The Effects of Attention-Deficit/Hyperactivity Disorder Symptoms on the Association between Head Impacts and Post-Season Neurocognitive and Behavioral Outcomes
Authors: Lynch James D. , Narad Megan E. , Diekfuss Jed A. , Avedesian Jason , Zuleger Taylor M. , Peugh James , Myer Gregory D. , Epstein Jeffery N. 
Published: February 2022

AbstractObjective:Having attention-deficit/hyperactivity disorder (ADHD) is a risk factor for concussion that impacts concussion diagnosis and recovery. The relationship between ADHD and repetitive subconcussive head impacts on neurocognitive and behavioral outcomes is less well known. This study evaluated the role of ADHD as a moderator of the association between repetitive head impacts on neurocognitive test performance and behavioral concussion symptoms over the course of an athletic season.Method:Study participants included 284 male athletes aged 13–18 years who participated in high school football. Parents completed the Strengths and Weaknesses of ADHD Symptoms and Normal Behavior (SWAN) ratings about their teen athlete before the season began. Head impacts were measured using an accelerometer worn during all practices and games. Athletes and parents completed behavioral ratings of concussion symptoms and the Attention Network Task (ANT), Digital Trail Making Task (dTMT), and Cued Task Switching Task at pre- and post-season.Results:Mixed model analyses indicated that neither head impacts nor ADHD symptoms were associated with post-season athlete- or parent-reported concussion symptom ratings or neurocognitive task performance. Moreover, no relationships between head impact exposure and neurocognitive or behavioral outcomes emerged when severity of pre-season ADHD symptoms was included as a moderator.Conclusion:Athletes’ pre-season ADHD symptoms do not appear to influence behavioral or neurocognitive outcomes following a single season of competitive football competition. Results are interpreted in light of several study limitations (e.g., single season, assessment of constructs) that may have impacted this study’s pattern of largely null results.
What is the Current and Future Status of Digital Mental Health Interventions?
Authors: Baños Rosa Mª , Herrero Rocío , Vara Mª Dolores 
Published: February 2022

Abstract
The prevalence of mental disorders continues to increase, especially with the advent of the COVID-19 pandemic. Although we have evidence-based psychological treatments to address these conditions, most people encounter some barriers to receiving this help (e.g., stigma, geographical or time limitations). Digital mental health interventions (e.g., Internet-based interventions, smartphone apps, mixed realities -virtual and augmented reality) provide an opportunity to improve accessibility to these treatments. This article summarizes the main contributions of the different types of digital mental health solutions. It analyzes their limitations (e.g., drop-out rates, lack of engagement, lack of personalization, lack of cultural adaptations) and showcases the latest sophisticated and innovative technological advances under the umbrella of precision medicine (e.g., digital phenotyping, chatbots, or conversational agents). Finally, future challenges related to the need for real world implementation of these interventions, the use of predictive methodology, and hybrid models of care in clinical practice, among others, are discussed.
Adolescent Involvement in Cybergossip: Influence on Social Adjustment, Bullying and Cyberbullying
Authors: García-Fernández Cristina María , Moreno-Moya Miriam , Ortega-Ruiz Rosario , Romera Eva M. 
Published: February 2022

Abstract
Gossip is a type of social behavior present in all types of social networks, and cybergossip is an emerging kind of online social behavior which can both promote and hinder relationships between peers. The aim of this study was to explore the relation between involvement in cybergossip and the development of behavior of social adjustment, bullying and cyberbullying (aggression and victimization), based on gender and age. A total of 510 secondary school students (49.4% girls) aged 12 to 17 years old (M = 14.01; SD = 1.38) were surveyed by self-report. Questionnaires validated with adolescents were used to measure bullying, social adjustment and cyberbullying. The results showed that a high prevalence of involvement in cybergossip was associated with bullying and cyberbullying behavior (aggression and victimization), with girls showing the greatest involvement in cybergossip. The discussion of the results focuses on the gender difference, as well as the importance of the need for training in the proper use of digital devices for social education and socialization.
Ionospheric Corrections for Satellite Altimetry ‐ Impact on Global Mean Sea Level Trends
Authors: Dettmering Denise , Schwatke Christian 
Published: February 2022

AbstractAtmospheric delay corrections for satellite altimetry measurements are essential for deriving highly accurate sea surface heights and reliable global mean sea level (GMSL) trend estimates. A commonly used method to correct for ionospheric path delays are the usage of GNSS‐based Global Ionospheric Maps (GIM). The different orbit heights of GNSS and altimeter satellites require an adaption of GIM corrections to account for free electrons in the Earth plasmasphere. This study shows that the widely used scaling approach based on the International Reference Ionosphere (IRI) is not able to accurately scale the GIM models. The impact of neglecting the plasmaspheric part of the atmosphere strongly correlates with the solar activity of about 11 years. This manifests itself as trend errors in global GMSL. For the Jason period (2002–2021) a trend error of 0.17 mm/year can be shown, which is even larger for smaller periods (e.g., 1.0 mm/year for Jason‐1 lifetime). The application of an additional constant scaling factor of 0.886 can reduce the trend differences to below 0.05 mm/year.
Radial Interplanetary Magnetic Field‐Induced North‐South Asymmetry in the Solar Wind‐Magnetosphere‐Ionosphere Coupling: A Case Study
Authors: Park Jong‐Sun , Shi Quan Qi , Shi Xueling , Shue Jih‐Hong , Degeling Alexander W. , Nowada Motoharu , Tian An Min , Kim Khan‐Hyuk , Pitkänen Timo , Zhang Yongliang 
Published: February 2022

AbstractIn this paper, we present a case study of the radial interplanetary magnetic field (IMF Bx)‐induced asymmetric solar wind‐magnetosphere‐ionosphere (SW‐M‐I) coupling between the northern and southern polar caps using ground‐based and satellite‐based data. Under prolonged conditions of strong earthward IMF on 5 March 2015, we find significant discrepancies between polar cap north (PCN) and polar cap south (PCS) magnetic indices with a negative bay‐like change in the PCN and a positive bay‐like change in the PCS. The difference between these indices (PCN‐PCS) reaches a minimum of −1.63 mV/m, which is approximately three times higher in absolute value than the values for most of the time on this day (within ±0.5 mV/m). The high‐latitude plasma convection also shows an asymmetric feature such that there exists an additional convection cell near the noon sector in the northern polar cap, but not in the southern polar cap. Meanwhile, negative bays in the north‐south component of ground magnetic field perturbations (less than 50 nT) observed in the nightside auroral region of the Northern Hemisphere are accompanied with the brightening and widening of the nightside auroral oval in the Southern Hemisphere, implying a weak, but clear energy transfer to the nightside ionosphere of both hemispheres. After the hemispheric asymmetries in the polar caps disappear, a substorm onset takes place. All these observations indicate that IMF Bx‐induced single lobe reconnection that occurred in the Northern Hemisphere plays an important role in hemispheric asymmetry in the energy transfer from the solar wind to the polar cap through the magnetosphere.
The Role of Slow Slip Events in the Cascadia Subduction Zone Earthquake Cycle
Authors: Saux Juliette P. , Molitors Bergman Elias G. , Evans Eileen L. , Loveless John P. 
Published: February 2022

AbstractSlow slip events (SSEs) detected on the Cascadia Subduction Zone interface at 30–50 km depth imply a release of accumulated strain. However, studies of interseismic deformation in Cascadia typically find coupling on the upper 30 km of the interface, which is generally accepted as defining the seismogenic zone. Estimates of coupling using net interseismic velocities (including SSE effects) and restricting coupling to the shallow interface may underestimate slip deficit accumulation at depths >30 km. Here, we detect reversals in GPS motion as indications of SSEs, then use SSE displacements to estimate cumulative slow slip from 2007 to 2021. We calculate pure interseismic velocities, correcting for SSE displacements, and use them to constrain an elastic block model, estimating slip deficit on the subduction interface down to 50 km. By evaluating slip deficit and slow slip independently, we examine SSEs’ effect on interseismic strain accumulation, and the effect of inter‐SSE slip deficit and slow slip on vertical deformation of the forearc. We find that moderate to high coupling extends to 40 km depth, and while shallow coupling is consistent with previous estimates of the seismogenic zone, a deeper region of slip deficit beneath the Olympic Peninsula may be partially (61%) relieved aseismically by SSEs. Patterns of surface uplift suggest that complete relief of deep coupling over multiple decades may be accomplished by time‐varying rates of aseismic slip.
Seismic Wave Propagation in Partially Saturated Rocks With a Fractal Distribution of Fluid‐Patch Size
Authors: Zhang Lin , Ba Jing , Carcione José M. , Wu Chunfang 
Published: February 2022

AbstractLaboratory experiments on partially saturated rocks show that seismic attenuation can be significant. The main mechanism, wave‐induced local fluid flow (WILFF), is affected by the spatial fluid distribution, especially in conditions of patchy saturation at different spatial scales. We propose a theory to obtain the seismic properties of partially saturated rocks based on fractal (self‐similar) patches, leading to an effective frequency‐dependent fluid modulus. The model combines the differential effective medium and Biot‐Rayleigh theories, where the patches are inclusions incrementally added, such that the effective fluid calculated in the current addition serves as host fluid in the next one. The analysis shows that adding identical inclusions in one or several steps produces nearly the same results, but the seismic properties depend on the scale range (radius) of the inclusions, fractal dimension Df of the self‐similar distribution, parameter of the exponential distribution, mean radius r0 and variance of the Gaussian distribution. Forced‐oscillation experiments were performed on a limestone sample under partial water‐saturation conditions at seismic frequencies (2–500 Hz), to obtain the velocity dispersion and extensional attenuation. The proposed theory provided a reasonable description of these experimental data as well as other published measurements on tight carbonate and Berea sandstone.
Connecting the Oxidative Potential of Fractionated Particulate Matter With Chromophoric Substances
Authors: Wu Na , Lu Bingqing , Chen Qingcai , Chen Jianmin , Li Xiang 
Published: February 2022

AbstractParticulate matter (PM) air pollution is recognized as a major cause of adverse health outcomes, yet much remains unknown about which fractions and compositions are the most harmful. Efforts in this direction can be improved by employing a cell‐free approach, dithiothreitol (DTT) assay, the so‐called oxidative potential (OP). Here, we provide a detailed examination of OP from fractionated PM by a combination extraction method of solvent and solid‐phase extractions (SPE). We estimate that the average OP of water‐soluble matter (WSM; 4.27 nmol/min/m3) is up to 1.2 times higher than methanol‐soluble matter (3.66 nmol/min/m3) in most seasons apart from summer. Of these WSM, OP is distributed almost equally between hydrophobic and hydrophilic fractions. OP of PM is mainly related to transition metals (Cu: 12.1%, Mn: 2.5%); apart from these, more than 80% of the total OP remains unidentified. Identification of this unexplained OP by a novel approach, integrating the chromophore characteristics with parallel factor analysis, has shown that chromophore1 (C1) accounted for 98% of OP, although this factor only made a small contribution to the total fluorescence. Our paper highlights the importance of a holistic approach by evaluating the chemical structure‐activity relationship between optical characteristics and OP. Information presented here draws a connection between light‐absorbing organic aerosols and a possible toxicological mechanism on the basis of their optical properties.
Secondary Minerals Drive Extreme Lithium Isotope Fractionation During Tropical Weathering
Authors: Chapela Lara María , Buss Heather L. , Henehan Michael J. , Schuessler Jan A. , McDowell William H. 
Published: February 2022

AbstractLithium isotopes are used to trace weathering intensity, but little is known about the processes that fractionate them in highly weathered settings, where secondary minerals play a dominant role in weathering reactions. To help fill this gap in our knowledge of Li isotope systematics, we investigated Li isotope fractionation at an andesitic catchment in Puerto Rico, where the highest rates of silicate weathering on Earth have been documented. We found the lowest δ7Li values published to date for porewater (−27‰) and bulk regolith (−38‰), representing apparent fractionations relative to parent rock of −31‰ and −42‰, respectively. We also found δ7Li values that are lower in the exchangeable fraction than in the bulk regolith or porewater, the opposite than expected from secondary mineral precipitation. We interpret these large isotopic offsets and the unusual relationships between Li pools as resulting from two distinct weathering processes at different depths in the regolith. At the bedrock‐regolith transition (9.3–8.5 m depth), secondary mineral precipitation preferentially retains the lighter6Li isotope. These minerals then dissolve further up the profile, leaching6Li from the bulk solid, with a total variation of about +50‰withinthe profile, attributable primarily to clay dissolution. Importantly, streamwater δ7Li (about +35‰) is divorced entirely from these regolith weathering processes, instead reflecting deeper weathering reactions (>9.3 m). Our work thus shows that the δ7Li of waters draining highly weathered catchments may reflect bedrock mineralogy and hydrology, rather than weathering intensity in the regolith covering the catchment.