bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of leader depletion on leader performance: the mediating role of leaders’ trust beliefs and employees’ citizenship behaviors
Authors: Haesevoets Tessa , De Cremer David , De Schutter Leander , van Dijke Marius , Young Henry Robin , Lee Hun Whee , Johnson Russell , Chiang Jack Ting-Ju 
Published: November 2022

AbstractThe leadership role can be demanding and depleting. Using self-regulation and social exchange theory as a framework, we developed a three-step sequential mediation model that explains how feelings of depletion can degrade leaders’ own performance level, via the reciprocating behavior of their employees. Specifically, we hypothesized that leader depletion is negatively related to their trust beliefs. This lack of trust is expected to be reciprocated by employees in such a way that they display less citizenship behaviors towards their leader. These lowered citizenship behaviors are, in turn, predicted to negatively impact leader performance. Additionally, we hypothesized that these negative effects of feeling depleted are more pronounced for leaders who believe that their willpower is limited. Studies 1 and 2 illustrated that leader depletion indirectly influences their own performance level through leaders’ trust beliefs and employees’ leader-directed citizenship behaviors. Study 3 extended these findings from the inter-individual to the intra-individual level, and demonstrated the predicted moderating role of belief in limited willpower. Together, our studies provide new and useful insights in the broader, more distal implications of leader depletion, which have not yet been considered in existing self-regulation models.
Multiple invasions, Wolbachia and human-aided transport drive the genetic variability of Aedes albopictus in the Iberian Peninsula
Authors: Lucati Federica , Delacour Sarah , Palmer John R.B. , Caner Jenny , Oltra Aitana , Paredes-Esquivel Claudia , Mariani Simone , Escartin Santi , Roiz David , Collantes Francisco , Bengoa Mikel , Montalvo Tomàs , Delgado Juan Antonio , Eritja Roger , Lucientes Javier , Albó Timor Andreu , Bartumeus Frederic , Ventura Marc 
Published: November 2022

AbstractThe Asian tiger mosquito,Aedes albopictus, is one of the most invasive species in the world. Native to the tropical forests of Southeast Asia, over the past 30 years it has rapidly spread throughout tropical and temperate regions of the world. Its dramatic expansion has resulted in public health concerns as a consequence of its vector competence for at least 16 viruses. Previous studies showed thatAe. albopictusspread has been facilitated by human-mediated transportation, but much remains unknown about how this has affected its genetic attributes. Here we examined the factors that contributed to shaping the current genetic constitution ofAe. albopictusin the Iberian Peninsula, where the species was first found in 2004, by combining population genetics and Bayesian modelling. We found that both mitochondrial and nuclear DNA markers showed a lack of genetic structure and the presence of worldwide dominant haplotypes, suggesting regular introductions from abroad. Mitochondrial DNA showed little genetic diversity compared to nuclear DNA, likely explained by infection with maternally transmitted bacteria of the genusWolbachia. Multilevel models revealed that greater mosquito fluxes (estimated from commuting patterns and tiger mosquito population distribution) and spatial proximity between sampling sites were associated with lower nuclear genetic distance, suggesting that rapid short- and medium-distance dispersal is facilitated by humans through vehicular traffic. This study highlights the significant role of human transportation in shaping the genetic attributes ofAe. albopictusand promoting regional gene flow, and underscores the need for a territorially integrated surveillance across scales of this disease-carrying mosquito.
Part three: a randomized study to assess biomarker changes in cigarette smokers switched to Vuse Solo or Abstinence
Authors: Kanobe Milly N. , Jones Bobbette A. , Nelson Paul , Brown Buddy G. , Chen Peter , Makena Patrudu , Schmidt Eckhardt , Darnell John , Caraway John W. , Prasad G. L. , Nordskog Brian , Round Elaine K. 
Published: November 2022

AbstractBiomarkers of exposure (BoE) can help evaluate exposure to combustion-related, tobacco-specific toxicants after smokers switch from cigarettes to potentially less-harmful products like electronic nicotine delivery systems (ENDS). This paper reports data for one (Vuse Solo Original) of three products evaluated in a randomized, controlled, confinement study of BoE in smokers switched to ENDS. Subjects smoked their usual brand cigarette ad libitum for two days, then were randomized to one of three ENDS for a 7-day ad libitum use period, or to smoking abstinence. Thirteen BoE were assessed at baseline and Day 5, and percent change in mean values for each BoE was calculated. Biomarkers of potential harm (BoPH) linked to oxidative stress, platelet activation, and inflammation were also assessed. Levels decreased among subjects randomized to Vuse Solo versus Abstinence, respectively, for the following BoE: 42–96% versus 52–97% (non-nicotine constituents); 51% versus 55% (blood carboxyhemoglobin); and 29% versus 96% (nicotine exposure). Significant decreases were observed in three BoPH: leukotriene E4, 11-dehydro-thromboxane B2, and 2,3-dinor thromboxane B2 on Day 7 in the Vuse Solo and Abstinence groups. These findings show that ENDS use results in substantially reduced exposure to toxicants compared to smoking, which may lead to reduced biological effects.
Solvent-sensitive nanoparticle-enhanced PCR assay for the detection of enterotoxigenic Escherichia coli
Authors: Teawprasong Patcharapong , Wongngam Yodsathorn , Tangchaikeeree Tienrat , Elaissari Abdelhamid , Tangboriboonrat Pramuan , Polpanich Duangporn , Jangpatarapongsa Kulachart 
Published: November 2022

AbstractStimulus-responsive nanoparticles are among the most utilized nanoscale materials in biomedical applications. As these nanoparticles exhibit a manipulable response to a particular stimulus, such as pH, heat, and organic solvent, they are potential signalling units in diagnostic assays. This study aims to enhance the limit of detection and reduce the turnaround time of magnetic nanoparticle polymerase chain reaction (PCR) enzyme-linked gene assay (MELGA), an advanced PCR-based technique termed the solvent-sensitive nanoparticle (SSNP)-enhanced PCR assay. This technique was proposed to detect pathogenic enterotoxigenic Escherichia coli (ETEC) through applying stimulus-responsive nanoparticles. The SSNPs were elaborated with three main components, including mesoporous silica nanoparticles as a structural unit, organic dye (Nile red) as a payload, and the corresponding organic solvent-sensitive polymer shell as “gatekeeper” (poly(maleic anhydride-alt-methyl vinyl ether, PMAMVE). A suitable organic solvent capable of inducing polymer swelling and dye dissolution was investigated by considering a solubility parameter. Using ethanol, the encapsulated Nile red can diffuse out of the SSNPs faster than other solvents and reach a constant concentration within 15 min. For the PCR inhibition study, various SSNPs concentrations (10–30 μg/reaction) were mixed with the ETEC gene and PCR reagent. The results showed that the particles in this concentration range did not inhibit PCR. By comparing the efficacy of conventional PCR, MELGA, and SSNP-enhanced PCR assay, the proposed technique showed a better detection limit than that of PCR, whereas that of MELGA was the lowest. Moreover, compared to MELGA or conventional PCR, this technique provided remarkably faster results in the postamplification process.
Development of an ultrasound guided focused ultrasound system for 3D volumetric low energy nanodroplet-mediated histotripsy
Authors: Glickstein Bar , Aronovich Ramona , Feng Yi , Ilovitsh Tali 
Published: November 2022

AbstractLow pressure histotripsy is likely to facilitate current treatments that require extremely high pressures. An ultrasound guided focused ultrasound system was designed to accommodate a rotating imaging transducer within a low frequency therapeutic transducer that operates at a center frequency of 105 kHz. The implementation of this integrated system provides real-time therapeutic and volumetric imaging functions, that are used here for low-cost, low-energy 3D volumetric ultrasound histotripsy using nanodroplets. A two-step approach for low pressure histotripsy is implemented with this dual-array. Vaporization of nanodroplets into gaseous microbubbles was performed via the 1D rotating imaging probe. The therapeutic transducer is then used to detonate the vaporized nanodroplets and trigger potent mechanical effects in the surrounding tissue. Rotating the imaging transducer creates a circular vaporized nanodroplet shape which generates a round lesion upon detonation. This contrasts with the elongated lesion formed when using a standard 1D imaging transducer for nanodroplet activation. Optimization experiments show that maximal nanodroplet activation can be achieved with a 2-cycle excitation pulse at a center frequency of 3.5 MHz, and a peak negative pressure of 3.4 MPa (a mechanical index of 1.84). Vaporized nanodroplet detonation was achieved by applying a low frequency treatment at a center frequency of 105 kHz and mechanical index of 0.9. In ex-vivo samples, the rotated nanodroplet activation method yielded the largest lesion area, with a mean of 4.7 ± 0.5 mm2, and a rounded shape. In comparison, standard fixed transducer nanodroplet activation resulted in an average lesion area of 2.6 ± 0.4 mm2, and an elongated shape. This hybrid system enables to achieve volumetric low energy histotripsy, and thus facilitates the creation of precise, large-volume mechanical lesions in tissues, while reducing the pressure threshold required for standard histotripsy by over an order of magnitude.
The effect of B-type allatostatin neuropeptides on crosstalk between the insect immune response and cold tolerance
Authors: Lubawy Jan , Hornik Justyna 
Published: November 2022

AbstractInsects are the largest group of arthropod phyla and are capable of surviving in a variety of environments. One of the most important factors in enabling them to do so is their resistance to temperature stress, i.e., cold tolerance. The neuroendocrine system, together with the immune system, cooperates to regulate a number of physiological processes that are essential for the stability of the organism in stressful conditions. However, to date, no one has studied the effect of insect myoinhibitory peptides (MIPs) on cold stress tolerance and immune system activity. Here, we investigated the effect of Tenmo-MIP 5 (10–6 M), cold stress (− 5 °C) and a combination of both on the immune response of Tenebrio molitor. All three treatments caused upregulation of immune-related genes (antimicrobial peptides and Toll) and increased phagocytosis activity (by approximately 10%). However, phenoloxidase activity and mortality were increased only after peptide injection and the combination of both treatments. The peptide injection combined with cold stress caused 40% higher mortality than that in the control. Together, our results show the links between cold stress, MIPs activity and the immune response, and to our knowledge, this is the first report showing the effect of MIP on the insect immune system.
Enhancing the Australian Gridded Climate Dataset rainfall analysis using satellite data
Authors: Chua Zhi-Weng , Evans Alex , Kuleshov Yuriy , Watkins Andrew , Choy Suelynn , Sun Chayn 
Published: November 2022

AbstractRainfall estimation over large areas is important for a thorough understanding of water availability, influencing societal decision-making, as well as being an input for scientific models. Traditionally, Australia utilizes a gauge-based analysis for rainfall estimation, but its performance can be severely limited over regions with low gauge density such as central parts of the continent. At the Australian Bureau of Meteorology, the current operational monthly rainfall component of the Australian Gridded Climate Dataset (AGCD) makes use of statistical interpolation (SI), also known as optimal interpolation (OI) to form an analysis from a background field of station climatology. In this study, satellite observations of rainfall were used as the background field instead of station climatology to produce improved monthly rainfall analyses. The performance of these monthly datasets was evaluated over the Australian domain from 2001 to 2020. Evaluated over the entire national domain, the satellite-based SI datasets had similar to slightly better performance than the station climatology-based SI datasets with some individual months being more realistically represented by the satellite-SI datasets. However, over gauge-sparse regions, there was a clear increase in performance. For a representative sub-domain, the Kling-Gupta Efficiency (KGE) value increased by + 8% (+ 12%) during the dry (wet) season. This study is an important step in enhancing operational rainfall analysis over Australia.
Blockade of CXXC5-dishevelled interaction inhibits adipogenic differentiation, obesity, and insulin resistance in mice
Authors: Seo Seol Hwa , Lee Dasung , Lee Soung-Hoon , Choi Kang-Yell 
Published: November 2022

AbstractObesity has become a major risk factor for developing metabolic diseases, including insulin resistance, type 2 diabetes, and hypertension. Growing pieces of evidence indicate that the Wnt/β-catenin signaling pathway plays an important role in adipogenesis and obesity. Activation of the Wnt/β-catenin signaling pathway inhibits adipogenesis by suppressing the differentiation of committed preadipocytes into mature adipocytes. CXXC5 is highly induced with suppression of Wnt/β-catenin signaling in early adipogenic differentiation. In addition, silencing CXXC5 in vitro increased β-catenin and decremented the major adipogenic differentiation markers. KY19334, a small molecule that activates the Wnt/β-catenin pathway via inhibition of CXXC5- Dishevelled (Dvl) protein–protein interaction (PPI), suppressed adipogenic differentiation. Administration of KY19334 ameliorated obesity by 26 ± 1.3% and insulin resistance by 23.45 ± 7.09% and reduced adipocyte hypertrophy by 80.87 ± 5.30% in high-fat diet (HFD)-fed mice. In addition, KY19334 accelerated the browning of adipose tissue and promoted hepatic glucose homeostasis in HFD-fed mice. In conclusion, activation of the Wnt/β-catenin signaling by inhibiting the interaction of CXXC5 and Dvl by small molecule-mediated interference is a potential therapeutic approach for treating obesity and insulin resistance.
Psychosocial Impact of the COVID-19 Pandemic on Children With Cochlear Implants and Their Parents/Family Members
Authors: Cesur Sıdıka , Topcu Merve Torun , Kalcıoğlu Mahmut Tayyar 
Published: November 2022

Purpose:
The purpose of this study was to describe hearing health care and education experiences of children with cochlear implants (CIs) during the COVID-19 pandemic and the potential psychosocial effects of the pandemic on these children and their parents/family members.

Method:

The study used a cross-sectional survey design. The study sample comprised two groups, namely, parents/family members of children with CIs (study group,
n
= 70,
M
age
= 44.6 ± 12.4 years) and parents/family members of children with normal hearing (control group,
n
= 58,
M
age
= 43.8 ± 11.5 years). Parents/family members completed the Perceived Stress Scale (PSS), the Coronavirus Anxiety Scale (CAS), and the Family Perspective Profile form, as well as the Demographic Information form.

Results:

The PSS scores of the study group were higher than those of the control group (
p
= .001). However, there was no statistically significant difference between groups in the CAS scores (
p
= .896). According to the Family Perspective Profile form, almost half of the parents/family members of children with CIs reported that their children experienced difficulties in education and hearing health care services during the pandemic and showed some changes in their attitudes and behaviors.

Conclusions:
During the pandemic, the stress levels of parents/family members of children with CIs were higher than parents/family members of children with normal hearing. In addition to the challenges posed by the pandemic, the difficulties that parents/family members of children with CIs experience in meeting their children's additional needs related to accessing education and hearing health care services may have contributed to increased stress levels.
A Tutorial for Speech-Language Pathologists: Physical Activity and Social Engagement to Prevent or Slow Cognitive Decline in Older Adults
Authors: Everly Janet , Plummer Jamie , Lohman Matthew , Neils-Strunjas Jean 
Published: November 2022

Purpose:
This tutorial provides an overview of two behavioral approaches, physical activity and social engagement, to prevent or slow cognitive decline in older adults and to increase awareness in the field of speech-language pathology of the important role that speech-language pathologists (SLPs) play in an interprofessional team working with this population.

Method:
A review of exercise science, neuroscience, and social science literature was used to synthesize evidence and to outline the impact of physical activity and social engagement on cognition. The following topics were explored: How do exercise and social engagement support cognition? What are modifiable risk factors of dementia? What is the impact of inactivity and isolation on cognition? What is the potential role of the SLP on an interprofessional team focusing on preventive measures for cognitive decline? What is the impact of physical exercise and social engagement on nursing home residents?

Results:
Research increasingly points to the critical importance of physical activity and social engagement to prevent cognitive decline in normal aging and to slow cognitive decline associated with mild cognitive impairment and dementia. Research suggests that physical activity maintains or improves memory, attention, executive function, visuospatial function, speed of processing, and general cognitive function. Social engagement has been found to maintain and improve general cognitive function.

Conclusions:
Behavioral interventions are an effective strategy to prevent or slow cognitive decline in the older adult population. SLPs have a role to play on an interprofessional team that works to prevent cognitive decline. By considering factors that play a role in the prevention of cognitive decline, such as physical activity and social engagement, the quality of life and overall health of older adults can be improved. Areas of improvement include memory, attention, executive function, visuospatial function, speed of processing, and general cognitive function.
The Effects of Symbol Format and Psycholinguistic Features on Receptive Syntax Outcomes of Children Without Disability
Authors: Brock Kris L. , Zolkoske Jamie , Cummings Alycia , Ogiela Diane A. 
Published: November 2022

Purpose:The graphic symbol is the foundation of augmentative and alternative communication (AAC) for many preliterate individuals; however, research has focused primarily on static graphic symbol sequences despite mainstream commercial technologies such as animation. The goal of this study was to compare static and animated symbol sequences across receptive communication outcome measures and psycholinguistic features (e.g., word frequency).Method:A counterbalanced, 2 × 2 × 2 mixed design was used to investigate the effects of symbol format (animated and static), first condition (animated or static), and first experimental task (identification or labeling) on identification accuracy and labeling accuracy of graphic symbol sequences (five symbols) in 24 children with typical development ages 7 and 8 years old. Additionally, three 2 × 2 repeated-measures analyses of variance were conducted using symbol format (animated and static) and (a) word frequency (low, high), (b) imageability (low, high), and (c) concreteness (low, high).Results:In addition to superior identification and labeling accuracy of animated sequences, a significant interaction between symbol format and the first condition was observed for both experimental tasks. When the animation format was the first condition, then the children's performance improved in the subsequent static condition. Finally, word frequency, imageability, and concreteness ratings for all verbs and prepositions had significant effects on labeling accuracy of verbs and prepositions. Significant interactions between symbol format and psycholinguistic features were also found. For example, highly imageable, animated verbs were labeled with greater accuracy when compared with all other variables.Conclusions:Animation technology appears to alleviate some of the burden associated with word- and sentence-level outcomes in children with typical development. Moreover, animation appears to reduce the effects of psycholinguistic features such as word frequency and imageability by increasing the transparency of the symbol. Given the increase in research in this area, speech-language pathologists may consider adopting animated graphic symbols on a case-by-case basis as a tool to augment the learning of word classes in which movement is integral to comprehension.
Estimating the spectral abscissa for switched linear systems via square coordinate transformations
Authors: Lin Meili , Han Junfeng , Xu Yong 
Published: November 2022

AbstractSwitched linear systems are important in providing a convenient method to represent many practical systems. This paper investigates the performance analysis of switched linear systems under arbitrary switching. Computational algorithms based on square coordinate transformations are presented to obtain the least μ1 measure. Theoretical results showed that sequences of the least μ1 matrix set measure obtained by two different algorithms are convergent and the limit gives an upper bound estimation of the spectral abscissa. A numerical example is presented to show the effectiveness of the proposed method.
A hybrid scheme for optimal performance of photovoltaic system converters with multilayer structure
Authors: Zand Mohammad , Nasab Morteza Azimi , Hanif Hamid Reza , Ghahri Muhammad Reza , Padmanaban Sanjeevikumar , Khan Baseem 
Published: November 2022

AbstractThe interface of photovoltaic (PV) systems to the grid requires an efficient control strategy to operate, control, and improve power quality. The output voltage of the solar array, which may be accompanied by significant voltage variations, must be controlled and converted to a higher voltage for grid connection applications of photovoltaic system by a DC‐DC converter that commands more attention. Recently, due to the increasing use of renewable sources, multilayer structure with different structures and designs to provide power and stability has been researched because the output voltage of solar arrays is usually low, so it is increasing to DC‐to‐DC converters, needed with optimal interest and efficiency. In this paper, a method to improve the performance of DC–DC converter used in PV system by using a combined design of forward and fly‐back is presented. Due to the fact that isolated converters, flyback, and forward converters have a simple structure and are easy to control, but this converter is affected by high stress voltage. Therefore, this converter cannot be used for high power applications. To solve this problem, it has been improved in the proposed converter with the overlay and triple induction technique, which is a very good improvement on the voltage gain parameters in the short duty cycle. The voltage drop across the semiconductor switch is reduced. The investigations performed that the proposed DC/DC converter in Simulink MATLAB has been simulated. The results show that the suggested converter has an ideal efficiency of roughly 82.86% and provided higher voltage gain, decreased voltage stress, and reduced voltage jumps caused by disconnection.