bluuebunny/crossref_metadata_2025_split huggingface dataset:
Examining the role of China's outward direct investment in realizing carbon neutrality: empirical evidence from Belt and Road countries
Authors: Jiang Qingyan , Yang Cuihong , Wu Jie , Xia Yan 
Published: March 2022

PurposeKnown as the major capital providers in Belt and Road countries and the largest carbon emitter in the world, what role China's outward direct investment (ODI) plays in carbon neutralization has become a matter of concern. This study aims to measure the impact of China's ODI on the carbon emissions of Belt and Road countries.Design/methodology/approachBased on an econometric model and an inter-regional input–output model, a new model measuring the carbon emission effects of ODI is developed.FindingsThe empirical results show that (1) in general, China's ODI generates an emission-reduction effect in Belt and Road countries; (2) The relationship between the emission-reduction effect and income level of host countries shows an approximate inverted U-shaped trend; and (3) China's ODI generates stronger emission-reduction effects on capital-intensive industries.Originality/valueThis study quantitatively measures the scale of carbon emission-increase and reduction effect, which is relatively lacking in previous studies. This study explores the heterogeneity from the perspectives of regions, countries and industries. The authors have compiled an inter-regional input–output table for the Belt and Road countries for 2014 to provide a broad basis for the study of related issues.
Synthesis and temperature-sensitive lubrication behavior of PNIPAM microgels for titanium alloy
Authors: Xu Yufu , Sun Kequn , Zheng Quan , Yao Lulu , Dong Yinghui , Song Ruhong 
Published: March 2022

Purpose
This paper aims to offeri novel nano-additives polymer microgels to precisely improve the lubrication properties of titanium alloy under different temperatures.

Design/methodology/approach
The surfactant-free emulsion polymerization method was used to prepare Poly(N-isoprolylacrylamide) (PNIPAM) microgels. A ball-on-disk tribometer was applied to investigated the temperature-sensitive lubrication behavior of PNIPAM microgels.

Findings
The results show that the as-prepared microgels are ball-like nanoparticles with the size of 50–900 nm. In addition, potassium persulfate as initiator, complete mixing technic and high sodium dodecyl sulfate (SDS) concentration contribute to the formation of microgels with small size. The tribosystem shows a lower friction coefficient with the lubrication of PNIPAM microgels as aqueous solution additives when the temperature exceeding the critical temperature.

Originality/value
This work reports the temperature-sensitive lubrication of PNIPAM microgels. The critical temperature of PNIPAM microgels could be regulated by the addition of SDS in the solutions. This offers an effective and facile strategy for regulation of the critical temperature of smart microgels, which is helpful for the smart lubrication in the future.
Perceived corporate social responsibility and knowledge sharing: mediating roles of employees’ eudaimonic and hedonic well-being
Authors: Chtioui Rachèd , Berraies Sarra , Dhaou Amal 
Published: March 2022

Purpose
This study aims to develop a series of hypotheses that are tested based on a survey design methodology. Data collected from 281 knowledge workers operating in mid-level positions within knowledge-intensive firms (KIFs) operating in the information and communication technology (ICT) Tunisian sector was analysed through the partial-least square-structural equation modelling (method.

Design/methodology/approach
Drawing on the social identity and the social exchange theories, this study aims to examine the link between perceived corporate social responsibility (CSR) and knowledge sharing (KS) and the mediating effects of eudaimonic well-being (EWB) and hedonic well-being in this relationship.

Findings
Results indicate that perceived CSR among employees exerts a positive direct impact on KS, EWB and hedonic well-being. These two types of well-being are found to be key factors improving the willingness of employees to share their knowledge within the organization. Findings also revealed that EWB partially mediates the link between perceived CSR and KS.

Originality/value
This research pioneers the investigation of the mediating effects of eudaimonic and hedonic well-being between perceived CSR and KS that have never been examined. The results of this study provide practical insights for managers of KIFs regarding the CSR practices that may have a strong influence on employees’ hedonic and EWB and KS behaviour.
Early reduction of acute anterior shoulder dislocations in a ski field setting
Authors: Fraser Calum , Pellatt Richard , Shirran Mark , McKay Glenn , Smith Michael 
Published: March 2022

AbstractObjectiveThe present study describes the management of suspected shoulder dislocations in ski field clinics.MethodsData were collected from two clinics in Queenstown, New Zealand. Suspected anterior shoulder dislocations, with no suspicion of significant fractures and without imaging, underwent attempted reduction.ResultsNinety percent (n = 49) of dislocations were successfully relocated. No short‐term complications because of this procedure were observed.ConclusionThis short report raises the possibility that early anterior shoulder reduction in a ski field clinic can be safe without imaging, in select cases. Prospective studies including patient centred data are recommended.
Controlling International Institutions: How the US Engineered UNSC Non‐permanent Members in the Early Cold War
Authors: Balci Ali 
Published: March 2022

AbstractHow did the US shape the composition of the UN Security Council during the early Cold War period? By focusing on the election of non‐permanent members to Council seats, this paper investigates what role the US played in the nomination and election of candidate countries. In doing so, the study relies heavily on US diplomatic archives since those archival materials are rich in terms of voting preferences of UN members, negotiations between the US and its allies, and Washington's intensive lobbying for candidates. Investigating contested elections from 1946 to 1964, we find that although the US had an extensive influence on determining Council's non‐permanent members, its power to influence election outcomes dramatically weakened from the late 1950s onwards. This finding has important implications for the recent literature on the UN Security Council.
Metformin in nucleus accumbens core reduces cue‐induced cocaine seeking in male and female rats
Authors: Chan Amy , Willard Alexis , Mulloy Sarah , Ibrahim Noor , Sciaccotta Allegra , Schonfeld Mark , Spencer Sade M. 
Published: March 2022

AbstractThis study investigated the potential therapeutic effects of the FDA‐approved drug metformin on cue‐induced reinstatement of cocaine seeking. Metformin (dimethyl‐biguanide) is a first‐line treatment for type II diabetes that, among other mechanisms, is involved in the activation of adenosine monophosphate activated protein kinase (AMPK). Cocaine self‐administration and extinction is associated with decreased levels of phosphorylated AMPK within the nucleus accumbens core (NAcore). Previously, it was shown that increasing AMPK activity in the NAcore decreased cue‐induced reinstatement of cocaine seeking. Decreasing AMPK activity produced the opposite effect. The goal of the present study was to determine if metformin in the NAcore reduces cue‐induced cocaine seeking in adult male and female Sprague Dawley rats. Rats were trained to self‐administer cocaine followed by extinction prior to cue‐induced reinstatement trials. Metformin microinjected in the NAcore attenuated cue‐induced reinstatement in male and female rats. Importantly, metformin's effects on cocaine seeking were not due to a general depression of spontaneous locomotor activity. In female rats, metformin's effects did generalize to a reduction in cue‐induced reinstatement of sucrose seeking. These data support a potential role for metformin as a pharmacotherapy for cocaine use disorder but warrant caution given the potential for metformin's effects to generalize to a natural reward in female rats.
Cardiac rehabilitation in rural and remote areas of North Queensland: How well are we doing?
Authors: Field Patricia , Franklin Richard C. , Barker Ruth , Ring Ian , Leggat Peter A 
Published: March 2022

AbstractObjectiveTo address access to cardiac rehabilitation (CR) for people in R&R areas, this research aimed to investigate: (1) post discharge systems and support for people returning home from hospital following treatment for heart disease (HD). (2) propose changes to improve access to CR in R&R areas of NQ.SettingFour focus communities in R&R areas of NQ.ParticipantsFocus communities’ health staff (resident/visiting) (57), community leaders (10) and community residents (44), discharged from hospital in past 5 years following treatment for heart disease (purposeful sampling).DesignA qualitative descriptive case study, with data collection via semi‐structured interviews. Inductive/deductive thematic analysis was used to identify primary and secondary themes. Health service audit of selected communities.ResultsHealth services in the focus communities included multipurpose health services, and primary health care centres staffed by resident and visiting staff that included nurses, Aboriginal and Torres Strait Islander Health Workers, medical officers, and allied health professionals. Post‐discharge health care for people with HD was predominantly clinical. Barriers to CR included low referrals to community‐based health professions by discharging hospitals; poorly defined referral pathways; lack of guidelines; inadequate understanding of holistic, multidisciplinary CR by health staff, community participants and leaders; limited centre‐based CR services; lack of awareness, or acceptance of telephone support services.ConclusionTo address barriers identified for CR in R&R areas, health care systems’ revision, including development of referral pathways to local health professionals, CR guidelines and in‐service education, is required to developing a model of care that focuses on self‐management and education: Heart: Road to Health.
Association between caesarean birth and childhood cancer: An age‐lagged approach
Authors: Marcoux Sophie , Soullane Safiya , Lee Ga Eun , Auger Nathalie 
Published: March 2022

AbstractAimWe assessed the association between caesarean birth and age‐specific risks of childhood cancer.MethodsWe followed a cohort of 1 034 049 children between 2006 and 2020 in Quebec, Canada, from birth until age 14 years. The exposure was caesarean, operative vaginal, or spontaneous vaginal birth. The outcome included haematopoietic or solid tumours. We calculated hazard ratios (HR) and 95% confidence intervals (CI) for the association between mode of delivery and childhood cancer in age‐lagged analyses, adjusted for potential confounders.ResultsA total of 249 415 (24.1%) children were born by caesarean and 97 411 (9.4%) by operative vaginal delivery. Compared with spontaneous vaginal birth, caesarean was associated with 1.16 times the risk of any cancer (95% CI 1.04–1.30), 1.12 times the risk of haematopoietic cancer (95% CI 0.92–1.36) and 1.21 times the risk of solid tumours (95% 1.06–1.39). Associations strengthened at 2 years of age and were greatest for lymphoma and sarcoma. Operative vaginal birth was not significantly associated with the risk of cancer.ConclusionCaesarean birth may be associated with selected childhood cancers, including lymphoma and sarcoma early in childhood. The underlying reasons for the associations require further investigation, including whether mucosal dysbiosis or labour hormone exposure explain the excess risk.
Honokiol ameliorates cisplatin‐induced acute kidney injury via inhibition of mitochondrial fission
Authors: Mao Rui‐wen , He Shan‐ping , Lan Jun‐gang , Zhu Wu‐zheng 
Published: March 2022

Background and PurposeMitochondrial damage and oxidative stress are crucial contributors to the tubular cell injury and death in acute kidney injury. Novel therapeutic strategies targeting mitochondria protection and halting the progression of acute kidney injury are urgently needed. Honokiol is a small‐molecule polyphenol that exhibits extraordinary cytoprotective effects, such as anti‐inflammatory and anti‐oxidative. Thus, we investigated whether honokiol could ameliorate cisplatin‐induced acute kidney injury via preventing mitochondrial dysfunction.Experimental ApproachAcute kidney injury was induced by cisplatin administration. Biochemical and histological analysis were used to determine kidney injury. The effect of honokiol on mitochondrial function and morphology were determined using immunohistochemistry, transmission electron microscopy, immunoblot and immunofluorescence. To investigate the mechanism by which honokiol alters mitochondrial dynamics, remodelling and resistance to apoptosis, we used transfection experiments, immunoblotting, immunoprecipitation and flow cytometry assay.Key ResultsWe demonstrated that the prominent mitochondrial fragmentation occurred in experimental models of cisplatin‐induced nephrotoxicity, which was coupled to radical oxygen species (ROS) overproduction, deterioration of mitochondrial function, release of apoptogenic factors and the consequent apoptosis. Honokiol treatment caused notable reno‐protection and attenuated of these cisplatin‐induced changes. Mechanistically, honokiol treatment recovered the expression of SIRT3 and improved AMPK activity in tubular cells exposure to cisplatin, which preserved the Drp1 phosphorylation at Ser637 and blocked its translocation in mitochondria, consequently preventing mitochondrial fragmentation and subsequent cell injury and death.Conclusion and ImplicationsOur results indicate that honokiol may protect against cisplatin‐induced acute kidney injury by preserving mitochondrial integrity and function by SIRT3/AMPK‐dependent mitochondrial dynamics remodelling.
Distribution and geological controls of the seabed fluid flow system, the central‐western Bohai Sea: A general overview
Authors: Duan Minliang , Tong Siyou , Chen Jiangxin , Azevedo Leonardo , Li Rihui , Song Haibin , Liang Jie , Xu Huaning , Yang Rui , Liu Bin 
Published: March 2022

AbstractThorough understanding of seabed fluid flow system is of great significance to geohazard identification and hydrocarbon exploration as it can reshape the seabed and act as an indicator of subsurface hydrocarbon resources. For the first time, an integrated study of side‐scan sonar, single‐ and multi‐channel seismic data and magnetic data reveals a complex fluid flow system composed of various seafloor expressions (i.e. pockmarks and mounds) and shallow fluid migration pathways in the central‐west Bohai Sea off northeast China. Gas chimneys, mud diapirs and a dense network of Quaternary faults are the main fluid migration pathways in the shallow subsurface. The gas chimneys can be classified into three categories (Type A formed by relatively rapid gas escape, Type B formed by episodic fluid expulsion and Type C formed by fluid escape from mud diapirs), based on their distribution and seismic character, implying variability in the formation processes. Sediment remobilization and basement‐involved faults contribute to deep fluid migration into shallow depths. As a seal for up‐moving fluids, the nature and thickness of Holocene marine sediments generally decide the permeability and overburden pressure that may control the distribution of pockmarks and mounds since they are almost distributed above relatively thin Holocene deposits (thickness <20 m) and localized coarse surface sediments. The results of the interpretation gain an improved understanding of the geological processes controlling the genesis and spatial distribution of gas chimney formation and show the significance of gas chimney classification. The distribution pattern of different types of gas chimneys may signify the difference of geological background and fluid flow process, like fluid migration through faults or flow of mobilized sediments, that is crucial for the evaluation of global petroleum systems and Carbon Capture and Storage studies.
The importance of high performing team members in complex team work: Results from quasi‐experiments in professional team sports
Authors: Wegelin Philipp , Orlowski Johannes , Dietl Helmut M. 
Published: March 2022

AbstractThis paper empirically assesses peer effects of high performing team members in reciprocally interdependent team production. Using data from the National Basketball Association (NBA), we identify peer effects by exploiting unforeseen in‐game injuries of high performing players. Results indicate that without a high performing player, other team members maintain efficiency and the division of tasks among each other. However, they slightly increase risk taking and decrease their individual output, resulting in an inferior overall outcome. These effects depend on whether a high performing player has a team‐oriented or a self‐oriented role in the team. Additionally, we observe that relatively skilled players try to step in for the absent high performing player.
A new estimate of Chinese male occupational structure during 1734–1898 by sector, sub‐sector pattern, and region
Authors: Yang Cheng 
Published: March 2022

AbstractBased on the Xingke Tiben, this paper assesses the long‐run economic development of China, by constructing a new estimate of male occupational structure during 1734–1898 by sector, sub‐sector pattern, and region. After assessing the source's biases, using this new empirical basis, this paper demonstrates that the national male occupational structure was nearly identical in 1761–70, 1821–30, and 1881–90, suggesting a long‐lasting structural stasis of the national economy, allowing for fluctuations between benchmark dates. Within agriculture, substantial regional differences in labour organisation are revealed. Three distinct models are found: the Northern Regions model features a high usage of wage labour, the Yangtze Valley model presents a high level of tenancy development, and the Southern Regions model displays the highest share of landowners. All three models saw increasing use of wage labour in 1761–1890 and shrinking landownership in 1821–90. At the regional level, the long‐run estimate for Lower Yangtze suggests that the region as a whole stagnated throughout the entire period, but the overall structural stasis hides dynamic, contrasting long‐run economic change between the region's core and peripheral areas. Comparative analysis with England further suggests that the timing of the Great Divergence between China and England took place before 1734, even in the context of the regional difference.
A pharmacogenomic assessment of psychiatric adverse drug reactions to levetiracetam
Authors: Campbell Ciarán , McCormack Mark , Patel Sonn , Stapleton Caragh , Bobbili Dheeraj , Krause Roland , Depondt Chantal , Sills Graeme J. , Koeleman Bobby P. , Striano Pasquale , Zara Federico , Sander Josemir W. , Lerche Holger , Kunz Wolfram S. , Stefansson Kari , Stefansson Hreinn , Doherty Colin P. , Heinzen Erin L. , Scheffer Ingrid E. , Goldstein David B. , O'Brien Terence , Cotter David , Berkovic Samuel F. ,   The EpiPGX Consortium, Sisodiya Sanjay M. , Delanty Norman , Cavalleri Gianpiero L. 
Published: March 2022

AbstractObjectiveLevetiracetam (LEV) is an effective antiseizure medicine, but 10%–20% of people treated with LEV report psychiatric side‐effects, and up to 1% may have psychotic episodes. Pharmacogenomic predictors of these adverse drug reactions (ADRs) have yet to be identified. We sought to determine the contribution of both common and rare genetic variation to psychiatric and behavioral ADRs associated with LEV.MethodsThis case‐control study compared cases of LEV‐associated behavioral disorder (n = 149) or psychotic reaction (n = 37) to LEV‐exposed people with no history of psychiatric ADRs (n = 920). All samples were of European ancestry. We performed genome‐wide association study (GWAS) analysis comparing those with LEV ADRs to controls. We estimated the polygenic risk scores (PRS) for schizophrenia and compared cases with LEV‐associated psychotic reaction to controls. Rare variant burden analysis was performed using exome sequence data of cases with psychotic reactions (n = 18) and controls (n = 122).ResultsUnivariate GWAS found no significant associations with either LEV‐associated behavioural disorder or LEV‐psychotic reaction. PRS analysis showed that cases of LEV‐associated psychotic reaction had an increased PRS for schizophrenia relative to contr ols (p = .0097, estimate = .4886). The rare‐variant analysis found no evidence of an increased burden of rare genetic variants in people who had experienced LEV‐associated psychotic reaction relative to controls.SignificanceThe polygenic burden for schizophrenia is a risk factor for LEV‐associated psychotic reaction. To assess the clinical utility of PRS as a predictor, it should be tested in an independent and ideally prospective cohort. Larger sample sizes are required for the identification of significant univariate common genetic signals or rare genetic signals associated with psychiatric LEV ADRs.
The SedUROscopy Project: Sedation conducted by nurses supervised by the anaesthetist at a Lithotripsy and Endourology Unit in Spain
Authors: Arguedas Pilar , Cabello Teresa , Escuder Maite , Muñoz Maria Angeles , Orozco Luisa , Sales Elvira 
Published: March 2022

AbstractThe increased demand for simple, yet invasive and sometimes painful urological procedures in our unit, coupled with a relative lack of anaesthetists, prompted the search for appropriate safe alternatives to current practice, so to enable efficient, satisfactory, and safe interventions for patients. In response to this need, the Four‐Phase SedUROscopy Project has been developed, a plan in which identified Urology nurses take on a more active role in the anaesthetic procedure at the Lithotripsy and Endourology Unit. The aim of the project is to establish a specific care model that ensures the safety and satisfaction of patients undergoing minor endourological procedures, whilst also optimizing resources and empowering nurses and their practice. The SedUROscopy Project started with the training of five nurses (Phase 1: Theory). Subsequently, one of the nurses then began her practical course (Phase 2: up to 200 sedations). She carried out 90 sedations in patients in preparation for minor procedures. Remifentanil and Propofol were administrated using Target Controlled Infusion (TCI) pumps. The initial target plasma propofol concentration was 2 μg/ml, and the remifentanil one was 1 μg/ml. Doses were adjusted to achieve the right sedation. ECG, pulse oximetry, non‐invasive blood pressure and end‐tidal CO2 were monitored. Up to 10 different procedures were carried out. There were 37 oxygen desaturation events (41%), however they were solved with chin lift manoeuvres and mandibular subluxation (8.88%), use of Guedel tube (21.1%) and manual ventilation (11.1%). The intervention of the anaesthetist was not required in any of the cases, and all the patients involved in the sample were discharged the same day, free of any anaesthetic problem at all (100%). As the surveys indicated, the levels of satisfaction expressed by both patient and staff performing the technique were high (98%). The sedation performed by trained urology nurses using TCI has resulted in a provision of safe and effective procedures. Likewise, the patients' satisfaction was ensured. In conclusion, this model represents an optimal use of resources: not only because just a single anaesthetist could supervise two operation theatres, but also nurses could control the patients pain due to their knowledge of endourological procedures and the sedation technique.