bluuebunny/crossref_metadata_2025_split huggingface dataset:
DEVELOPING GENERAL REQUIREMENTS FOR A VARIABLE VOLUME CLIMATIC CHAMBER
Authors: Chervotoka О. , Herashchenko M. , Zayets І. , Dobryshkin Y. 
Published: October 2022

Problem statement. Analysis of Ukrainian standards, harmonized with NATO standards, has shown that during tests of armaments and military equipment, including armored vehicles and motor vehicles, is due to need to conduct tests for the effects of climatic factors. One of the types of testing for climatic factors is the determination of resistance to increase temperature, decrease temperature and increase humidity. To reproduce these conditions, climatic chambers of corresponding dimensions or variable volume chambers are used. The advantage of a climatic chamber with variable volume is its flexibility, i.e. depending on the overall dimensions of the test object its working volume can be changed, which in turn significantly reduces energy consumption and the time to reach the working mode of the chamber.
An important point when working out the general requirements for a climatic chamber of variable volume is to consider the requirements of international and national regulations in the field of defense. The most relevant are military standards that are harmonized with STANAG international military standards.
As of today, the Armed Forces of Ukraine lack measuring and testing facilities to assess armored vehicles and automotive equipment against the above-mentioned climatic characteristics. Creation of a climatic chamber of variable volume based on the developed general requirements will make it possible to obtain quantitative values of the characteristics to be assessed during tests.
The purpose of this article is to improve the efficiency of testing weapons and military equipment against external climatic factors by developing general requirements for a climatic chamber with variable volume.
Conclusions. The paper proposes general requirements for a climatic chamber with variable volume, which were worked out taking into account the requirements of international and national normative documents in the field of defense. The general requirements define the composition of the chamber, its purpose, basic tasks, possibilities, conditions of application, metrological assurance. Practical implementation of the obtained results consists in the possibility of their application during the development of tender documentation for the purchase of the chamber, which will ensure an increase in the efficiency of laboratory tests of various types of weapons and military equipment on the effects of climatic factors.
O Brasil feliz de novo: uma análise retórica do jingle do PT
Authors: Araujo Guilherme Leonardo 
Published: October 2022

O presente artigo apresenta uma análise retórica do jingle O Brasil feliz de novo. O objetivo da análise foi identificar como a canção foi construída para persuadir os eleitores a votarem no candidato do PT. A metodologia utilizada foi análise retórica elaborada por Leach (2010). Buscou-se identificar a construção da narrativa da letra do jingle em paralelo com os principais fatos que influenciaram o cenário político da campanha eleitoral de 2018. Concluiu-se que o principal elemento persuasivo presente na letra do jingle foi a emoção, gerada principalmente pelo grande número de metáforas presentes no jingle.
Clientélisme politique et recommandations
Authors: Bour Julie 
Published: October 2022

« Cli-en-té-lis-me », le mot est ancien, dure et perdure. Mais de quoi parle-t-on au juste? « Je connais tel élu et il a le bras long, il pourra me trouver une place à la mairie! » Si la phrase est courante, quelles réalités et quels fantasmes recouvre-t-elle précisément ?
Alors que le phénomène du clientélisme a déjà fait l’objet de plusieurs études en sociologie et sciences politiques, cette pratique originale a moins retenu l’attention des historiens du politique. Spécialiste de l’histoire politique française contemporaine, Julie Bour entend étudier les acteurs, causes, modalités et limites du clientélisme via une approche quantitative originale et inédite, reposant sur l’exploitation statistique de corpus importants de courriers de recommandation, dépassant parfois les milliers de lettres entre les élus et leurs administrés et portant sur des dossiers sensibles, symboliques ou plus prosaïques (emplois, décorations, service militaire, aide sociale, affaires communales, etc.). Elle concentre son analyse sur un espace test particulier qui est celui de la Lorraine et l’appréhende sur le temps long qui va de la IIIe République aux années 2000. Au travers d’études de cas portant sur des élus célèbres (Louis Jacquinot, Pierre Messmer, François Guillaume, Christian Pierret) ou plus anonymes (Jean Bernard, Jules Develle, André Savard) qui représentent l’ensemble des courants politiques, le clientélisme apparaît pour ce qu’il est réellement : une pratique très répandue (et non limité à un Sud méditerranéen arriéré), qui structure la vie politique locale, mobilise tout un réseau d’intercesseurs relais, crée des solidarités fines entre l’élu et les électeurs, et joue un rôle parfois déterminant dans l’élection et la longévité politique de certains parlementaires. Cette pratique, ancrée sur la durée, institutionnalisée au point d’être déculpabilisée, interroge la démocratie dans ses limites en termes de corruption et de clientélisme.
Human CD99L2 Regulates a Unique Step in Leukocyte Transmigration
Authors: Rutledge Nakisha S , Ogungbe Faith T , Watson Richard L , Sullivan David P , Muller William A 
Published: October 2022

Abstract
CD99-like 2 (CD99L2 [L2]) is a highly glycosylated 52-kDa type 1 membrane protein that is important for leukocyte transendothelial migration (TEM) in mice. Inhibiting L2 using function-blocking Ab significantly reduces the recruitment of leukocytes to sites of inflammation in vivo. Similarly, L2 knockout mice have an inherent defect in leukocyte transmigration into sites of inflammation. However, the role of L2 in inflammation has only been studied in mice. Furthermore, the mechanism by which it regulates TEM is not known. To study the relevance to human inflammation, we studied the role of L2 on primary human cells in vitro. Our data show that like PECAM and CD99, human L2 is constitutively expressed at the borders of endothelial cells and on the surface of leukocytes. Inhibiting L2 using Ab blockade or genetic knockdown significantly reduces transmigration of human neutrophils and monocytes across endothelial cells. Furthermore, our data also show that L2 regulates a specific, sequential step of TEM between PECAM and CD99, rather than operating in parallel or redundantly with these molecules. Similar to PECAM and CD99, L2 promotes transmigration by recruiting the lateral border recycling compartment to sites of TEM, specifically downstream of PECAM initiation. Collectively, our data identify a novel functional role for human L2 in TEM and elucidate a mechanism that is distinct from PECAM and CD99.
Synthetic Oligodeoxynucleotide CpG Motifs Activate Human Complement through Their Backbone Structure and Induce Complement-Dependent Cytokine Release
Authors: de Boer Eline , Sokolova Marina , Quach Huy Q , McAdam Karin E , Götz Maximilian P , Chaban Viktoriia , Vaage Jarle , Fageräng Beatrice , Woodruff Trent M , Garred Peter , Nilsson Per H , Mollnes Tom E , Pischke Søren E 
Published: October 2022

Abstract
Bacterial and mitochondrial DNA, sharing an evolutionary origin, act as danger-associated molecular patterns in infectious and sterile inflammation. They both contain immunomodulatory CpG motifs. Interactions between CpG motifs and the complement system are sparsely described, and mechanisms of complement activation by CpG remain unclear. Lepirudin-anticoagulated human whole blood and plasma were incubated with increasing concentrations of three classes of synthetic CpGs: CpG-A, -B, and -C oligodeoxynucleotides and their GpC sequence controls. Complement activation products were analyzed by immunoassays. Cytokine levels were determined via 27-plex beads-based immunoassay, and CpG interactions with individual complement proteins were evaluated using magnetic beads coated with CpG-B. In whole blood and plasma, CpG-B and CpG-C (p &lt; 0.05 for both), but not CpG-A (p &gt; 0.8 for all), led to time- and dose-dependent increase of soluble C5b-9, the alternative complement convertase C3bBbP, and the C3 cleavage product C3bc. GpC-A, -B, and -C changed soluble fluid-phase C5b-9, C3bBbP, and C3bc to the same extent as CpG-A, -B, and -C, indicating a DNA backbone–dependent effect. Dose-dependent CpG-B binding was found to C1q (r = 0.83; p = 0.006) and factor H (r = 0.93; p &lt; 0.001). The stimulatory complement effect was partly preserved in C2-deficient plasma and completely preserved in MASP-2–deficient serum. CpG-B increased levels of IL-1β, IL-2, IL-6, IL-8, MCP-1, and TNF in whole blood, which were completely abolished by inhibition of C5 and C5aR1 (p &lt; 0.05 for all). In conclusion, synthetic analogs of bacterial and mitochondrial DNA activate the complement system via the DNA backbone. We suggest that CpG-B interacts directly with classical and alternative pathway components, resulting in complement-C5aR1–dependent cytokine release.
Cytokine Receptor Diversity in the Lamprey Predicts the Minimal Essential Cytokine Networks of Vertebrates
Authors: Boulay Jean-Louis , Du Pasquier Louis , Cooper Max D 
Published: October 2022

Abstract
The vertebrate adaptive immune systems (Agnatha and Gnathostomata) use sets of T and B lymphocyte lineages that somatically generate highly diverse repertoires of Ag-specific receptors and Abs. In Gnathostomata, cytokine networks regulate the activation of lymphoid and myeloid cells, whereas little is known about these components in Agnathans. Most gnathostome cytokines are four-helix bundle cytokines with poorly conserved primary sequences. In contrast, sequence conservation across bilaterians has been observed for cognate cytokine receptor chains, allowing their structural classification into two classes, and for downstream JAK/STAT signaling mediators. With conserved numbers among Gnathostomata, human cytokine receptor chains (comprising 34 class I and 12 class II) are able to interact with 28 class I helical cytokines (including most ILs) and 16 class II cytokines (including all IFNs), respectively. Hypothesizing that the arsenal of cytokine receptors and transducers may reflect homologous cytokine networks, we analyzed the lamprey genome and transcriptome to identify genes and transcripts for 23 class I and five class II cytokine receptors alongside one JAK signal mediator and four STAT transcription factors. On the basis of deduction of their respective orthologs, we predict that these receptors may interact with 16 class I and 3 class II helical cytokines (including IL-4, IL-6, IL-7, IL-12, IL-10, IFN-γ, and thymic stromal lymphoprotein homologs). On the basis of their respective activities in mammals, this analysis suggests the existence of lamprey cytokine networks that may regulate myeloid and lymphoid cell differentiation, including potential Th1/Th2 polarization. The predicted networks thus appear remarkably homologous to those of Gnathostomata, albeit reduced to essential functions.
A elite econômica na produção do espaço urbano de Montes Claros/MG
Authors: Pereira Barbosa Eduardo Vinícius , Souza Beirão Éder de , Esdras Leite Marcos 
Published: October 2022

Este artigo tem como objetivo central analisar a concentração fundiária urbana de Montes Claros/MG. Para a consecução do objetivo, o presente trabalho considerou a formação da cidade em um trecho da área urbana denominado, historicamente, Fazenda Vargem Grande. Foi realizado o mapeamento da área da Fazenda Vargem Grande, a partir de seu desmembramento territorial, com inserção de dados dos atuais loteamentos que compõem o trecho. Procedeu-se, ainda, à coleta de dados do Ofício do 1º Registro de Imóveis de Montes Claros/MG referentes aos imóveis ali registrados que, no início da cadeia dominial, estavam compreendidos na Fazenda Grande, e, também, informações disponibilizadas pela Prefeitura Municipal de Montes Claros/MG, pelas plantas dos loteamentos, com elaboração de mapas. Nesse sentido, os resultados obtidos apontam a elite econômica de Montes Claros/MG com acesso à propriedade imobiliária num grande trecho da cidade, bem como as implicações concernentes à formação de um espaço urbano diante da concentração de terra, como a ocorrência de vazios urbanos e da especulação imobiliária.
Control de la hemorragia obstétrica secundaria a atonía uterina mediante doble técnica quirúrgica
Authors: Cárdenas José Eugenio Guerra , Sobrevilla-Tinajero Miguel Ángel , González-Pérez Brian , Ortiz Rafael Margarito Violante , Tapia Alejandra Tavera , Beltrán Elizabeth Reyna , López Claudia Penelope Mora 
Published: October 2022

INTRODUCCIÓN: Según la organización mundial de la salud, la hemorragia postparto es una de las principales razones de la mortalidad materna, especialmente en países en vías de desarrollo. La principal causa de hemorragia obstétrica postparto es la atonía uterina, que contribuye del 60% al 80% de la morbilidad materna extrema y del 20-30% de las muertes maternas. OBJETIVO: Comparar el empleo de técnica quirúrgica combinada mediante sutura compresiva de B-Lynch combinada con ligadura vascular mediante técnica de Posadas en pacientes atendidas en el Hospital General de Tampico Dr. Carlos Canseco. MÉTODOS: Estudio retrospectivo de casos y controles, en población obstétrica de cualquier edad, atendidas en el Hospital General de Tampico “Dr. Carlos Canseco” durante el periodo comprendido febrero 2018 – octubre 2020 que hayan presentado como complicación de su puerperio inmediato atonía uterina y per sé hayan tenido hemorragia obstétrica. El muestreo fue no probabilístico. Se incluyeron los expedientes de las mujeres obstétricas que llevaron su embarazo a término, y en cuyos casos se requirió el uso de maniobras por hemorragia obstétrica, independientemente de su causa, se incluyeron las pacientes con parto vaginal o por cesárea. RESULTADOS: Se obtuvo una muestra de 63 pacientes, de las cuales; 45 recibieron manejo médico (Grupo 1), 10 manejo quirúrgico mediante histerectomía obstétrica (Grupo 2) y 8 manejo quirúrgico conservador mediante ligadura de arterias uterinas combinado con B-Lynch modificado (Grupo 3). La técnica empleada en las pacientes si mostró evidencias significativas de riesgo, por ejemplo; los casos con histerectomía representaron prolongada estancia hospitalaria (p=0.000), mayor requerimiento de paquetes globulares (p=0.000) y riesgo de letalidad significativo (p=0.004). CONCLUSIONES: Los manejos quirúrgicos conservadores, como el utilizado en este estudio mediante sutura compresiva por la técnica de B-Lynch con la modificación realizada más la ligadura selectiva de las arterias uterinas por la técnica de Posadas si mostró efectividad en el control de la hemorragia obstétrica por atonía uterina, por lo que dicha técnica se puede recomendar como opción terapéutica escalonada, más no como primera línea de tratamiento.
(u)Mzantsi Classics: Dialogues in Decolonisation from Southern Africa
Authors: Masters Samantha , Nzungu Imkhitha , Parker Grant 
Published: October 2022

Though Graeco-Roman antiquity (‘classics’) has often been considered the handmaid of colonialism, its various forms have nonetheless endured through many of the continent’s decolonising transitions. Southern Africa is no exception. This book canvasses the variety of forms classics has taken in Zimbabwe, Mozambique and especially South Africa, and even the dynamics of transformation itself.
How does (u)Mzantsi classics (of southern Africa) look in an era of profound change, whether violent or otherwise? What are its future prospects? Contributors focus on pedagogies, historical consciousness, the creative arts and popular culture.
The volume, in its overall shape, responds to the idea of dialogue – in both the Greek form associated with Plato’s rendition of Socrates’ wisdom and in the African concept of ubuntu. Here are dialogues between scholars, both emerging and established, as well as students – some of whom were directly impacted by the Fallist protests of the late 20-teens.
Rather than offering an apologia for classics, these dialogues engage with pressing questions of relevance, identity, change, the canon, and the dynamics of decolonisation and potential recolonisation. The goal is to interrogate classics – the ways it has been taught, studied, perceived, transformed and even lived – from many points of view.
BARREIRAS PARA NÃO ADESÃO DAS GESTANTES AO RASTREAMENTO DO CÂNCER DO COLO DO ÚTERO DURANTE O PRÉ-NATAL
Authors: Costa Barbosa Tatiani , Gabriela Carvalho Brandão Alicia , Barbosa Furtado Dheison , Bruna Costa dos Santos Marcela , Dolores Rodrigues da Silva Maria , Vilanova Araújo Raquel 
Published: October 2022

Entende-se que o câncer de colo de útero acomete com frequência o público feminino e a principal estratégia para esse rastreamento é acompanhar o pré-natal desde o início. Nesse sentido, o presente estudo busca conhecer as barreiras para não adesão das gestantes ao rastreamento do câncer do colo do útero durante o pré-natal. A metodologia é baseada em um estudo de revisão integrativa de literatura, uma vez que, se construiu por meio de pesquisas nas bases de dados: Lilacs, Scopus, Scielo, Pubmed, Bdenf. Para a seleção dos estudos foram utilizados os Descritores em Ciências da Saúde, seus respectivos sinônimos e os Medical Subject Headings correspondentes. Com a presente pesquisa foi possível atingir os objetivos propostos, reconhecendo algumas das principais barreiras: a falta de conhecimento sobre a importância do exame, dificuldade para agendamento do exame, receio de realizar o exame com um profissional do sexo masculino, ideia de dano ao bebê, desconfortos emocionais como: timidez e associação à dor etc. Em todo caso, o estudo foi significativo e trouxe contribuições para a atuação da enfermagem.
Procurement Contract Management and Sustainable Performance of State Corporations in Kenya
Authors: Gatari Catherine Njoki , Shale Noor Ismail , Osoro Anthony Osoro 
Published: October 2022

Purpose: The purpose of this study was to establish the effect of procurement contract management on sustainable performance of state corporations in Kenya.
Methodology: The research design used in this research was mixed-methods research design. The study focused on 187 state corporation as the target population. Census was applied where all state corporations were surveyed and purposive sampling was used to pick the finance manager and the procurement manager which resulted to 374 respondents. The study main source of data was primary data which was gathered using research questionnaires. The gathered data was assessed with the help of Statistical Package for Social Sciences (SPSS) Version 28. The study carried out both descriptive and inferential analysis to draw conclusions.
Results: The inferential analysis results revealed that procurement contract management had a significant and positive influence on the sustainable performance of state corporations in Kenya at p<0.05. This indicates that contract preparation, contract administration, contract control and monitoring and contract conflicts resolution mechanisms are crucial drivers of sustainable performance of an organization. The model summary found that a unit change in procurement contract management may account for a variability of 45.1% in a firm's sustainable performance. The R value for the model was 0.670 and the R2 was 0.451. This was a sign that the model was appropriate for establishing the link between procurement contract management and sustainable performance and, as a result, for drawing the conclusions and suggestions from the study.
Unique Contribution to Theory, Practice and Policy: While the existing theory of public contracts used in this study was validated, the study recommends that the government through the appropriate regulatory agencies and the management of public procuring entities have the mandate to make sure that appropriate oversight of the management of contracts in state corporations is carried out as a means of ensuring accountability and justice throughout the entire process. According to the study, policymakers and state regulatory organizations should take the lead in making sure that contracts are properly documented and that they are diligently and effectively managed to ensure full adherence to the rules and regulations.
Evaluation of root resorption in maxillary anterior teeth during orthodontic treatment with a fixed appliance based on panoramic radiographs
Authors: Futyma-Gąbka Karolina , Różyło-Kalinowska Ingrid , Piskórz Magdalena , Bis Emanuela , Borek Wiktoria 
Published: October 2022

IntroductionThe aim of this study was to evaluate the frequency of apical root resorption in the anterior teeth of the maxilla visible on panoramic images during orthodontic treatment with a fixed appliance.Material and methodsA total of 194 panoramic radiographs of patients with a fixed appliance in the upper arch were analysed to evaluate the severity of root resorption in maxillary incisors and canines according to Levander and Malmgren classification. The research group included 135 females and 59 males, aged 15-28 years, with a mean 20.6 years.ResultsOf examined patients 75.26% had signs of apical root resorption. The tooth most frequently affected by resorptive changes was the right central upper incisor. The gender and age of the patients were not found to be significant factors. The highest number of teeth had second (II) stage root resorption (53.09%).ConclusionsPanoramic radiographs can be useful in diagnosing external apical root resorption due to orthodontic treatment.
EFEKTIFITAS PELAYANAN INSTALASI GAWAT DARURAT (IGD) PADA PUSKESMAS BLANG ASAN KECAMATAN PEUSANGAN TAHUN 2020-2021
Authors: Tanasah Suci Diana , Murniyanti Sri 
Published: October 2022

Pelayanan Kesehatan adalah upaya yang diselenggarakan oleh suatu organisasi untuk memelihara atau meningkatkan kesehatan, mencegah dan menyembuhkan penyakit serta memulihkan kesehatan individu, keluarga, kelompok, dan masyarakat. Efektivitas merupakan unsur pokok untuk mencapai tujuan atau sasaran yang telah ditentukan di dalam setiap organisasi. Kegiatan ataupun program disebut efektif apabila tercapai tujuan atau sasaran seperti yang telah ditentukan. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan jenis penelitian deskriptif. Penelitian ini dilakukan di Puskesmas Blang Asan Kecamatan Peusangan Tahun 2021-2022. Pemilihan Puskesmas ini sebagai lokasi penelitian didasarkan pada hasil penggambaran penelitian melalui pengalaman yang dialami oleh para informan terkait dengan efektivitas pelayanan Kesehatan di Puskesmas. Analisa data dalam penelitian ini diuraikan dengan indikator penelitian dalam kerangka berpikir bahwa konsep Efektivitas Pelayanan pada Instalasi Gawat Darurat di Puskesmas Blang Asan Kecamatan Peusangan Kabupaten Bireuen meliputi: kemampuan menyesuaikan diri, produktivitas kerja, kepuasan kerja, dan pemanfaatan sumber daya.
THÀNH PHẦN LOÀI THÂN MỀM CHÂN BỤNG (GASTROPODA: MOLLUSCA) Ở ĐẢO LAN CHÂU VÀ HÒN NGƯ TẠI CỬA LÒ, TỈNH NGHỆ AN
Authors: Nguyễn Thanh Bình , Đỗ Đức Sáng 
Published: October 2022

Nghiên cứu về thành phần loài Thân mềm Chân bụng trên cạn ở trên đảo Lan Châu và Hòn Ngư tại vùng biển Cửa Lò (Nghệ An) được tiến hành vào 8/2022. Kết quả phân tích được 5 loài, 5 giống và 4 họ. Qua nghiên cứu cho thấy các loài Thân mềm Chân bụng trên cạn tại khu vực nghiên cứu thường ở những nơi có nhiệt độ dao động từ 20,10C - 240C, độ ẩm dao động từ 85% - 89,1%.
Các loài Thân mềm Chân bụng trên cạn thường phân bố ở những nơi có lớp thảm mục dầy hoặc dưới các giá thể có ánh sáng thấp: Ở đảo Lan đã xác định được 4 loài, với mật độ trung bình của tất cả các loài là 30,3 cá thể/m2; tại đảo Hòn Ngư đã xác định được 3 loài với mật độ trung bình của tất cả các loài là 15,87 cá thể/m2. Kết quả nghiên cứu đã xác định được chỉ số đa dạng sinh học của Thân mềm Chân bụng trên cạn tại đảo Hòn Ngư ở mức độ kém đa dạng hơn đảo Lan Châu.