bluuebunny/crossref_metadata_2025_split huggingface dataset:
Análise da influência das autorizações de exploração de madeira no desmatamento da Amazônia Legal
Authors: Silveira de Almeida Dayse 
Published: January 2025

As áreas de floresta na Amazônia Legal vêm enfrentando aumentos na ocorrência de desmatamentos, seja por meio de corte raso, incêndios florestais, atividades de mineração e, até mesmo, corte seletivo para extração de madeira. Essa é uma região que requer atenção pela riqueza da sua biodiversidade e, a análise dos fatores que influenciam no desmatamento se faz necessária para que se possa alcançar um desenvolvimento social e econômico na região, respeitando as suas características culturais e em consonância com a preservação ambiental. Neste artigo, analisamos a relação entre as autorizações para exploração de madeira e o desmatamento em um estado da Amazônia Legal. Observamos que algumas instâncias de áreas autorizadas estão localizadas em setores urbanos. Apesar (i) das áreas autorizadas em setores urbanos se aproximarem mais rapidamente dos desmatamentos que as áreas autorizadas em setores rurais e, (ii) dos setores urbanos que possuem áreas autorizadas se aproximarem mais rapidamente dos desmatamentos, do que os setores urbanos que não possuem áreas autorizadas, o que sugere uma pressão maior sobre o desmatamento nesses setores, o tamanho das áreas desmatadas próximas às áreas autorizadas em setores rurais são maiores. Além disso, observamos que os volumes de madeira transportados a partir de áreas autorizadas em setores urbanos são maiores que os volumes transportados a partir de áreas autorizadas em setores rurais, ou seja, grande volume de madeira extraída dessas áreas autorizadas é transportado legalmente. Assim, especulamos se, (i) as áreas autorizadas em setores urbanos podem ser responsáveis por pequenos desmatamentos próximos com autorização legal e, (ii) as áreas autorizadas em setores rurais com menor volume de madeira transportado e aproximação mais lenta com as áreas desmatadas, sendo as áreas de desmatamento próximas, maiores, podem ter relação com o desmatamento ilegal.
ERBB2 as a Multifaceted Biomarker in Head and Neck Squamous Cell Carcinoma: In Silico and In Vitro Evidence
Authors: Raza Syed Hussain , Hameed Yasir 
Published: January 2025

Background: Head and neck squamous cell carcinoma (HNSC) is a prevalent and aggressive cancer, with ERBB2 (also known as HER2) being a gene of interest due to its role in various cancers. This study investigates the expression, promoter methylation, and potential prognostic significance of ERBB2 in HNSC, aiming to elucidate its role in the disease's progression and potential as a biomarker.
Methods: This study utilized multiple bioinformatics tools and databases, including UALCAN, GEPIA2, and cBioPortal, to perform expression and methylation analyses, survival assessments, and gene enrichment studies. Validation was conducted using RT-qPCR in HNSC and normal cell lines.
Results: ERBB2 expression was significantly down-regulated in HNSC samples compared to normal tissues. This down-regulation was consistent across various clinical parameters, including age, gender, race, and cancer stages. The ERBB2 promoter was significantly hypermethylated in HNSC samples compared to normal samples, providing a potential mechanism for its reduced expression. Kaplan-Meier analysis revealed that low ERBB2 expression was associated with poorer overall survival in HNSC patients. Functional enrichment analyses indicated that ERBB2 and its associated genes are involved in critical pathways such as the ErbB signaling pathway, EGFR tyrosine kinase inhibitor resistance, and the PI3K-Akt signaling pathway. Analysis of genetic mutations in ERBB2 showed a low mutation frequency (3%) in HNSC samples, suggesting a minor role of these mutations in disease progression. RT-qPCR analysis confirmed lower ERBB2 expression in HNSC cell lines (FaDu and Cal27) compared to normal control cell lines (HOK and HaCaT).
Conclusion: The study highlights the significant down-regulation and promoter hypermethylation of ERBB2 in HNSC, which correlates with poorer survival outcomes. These findings suggest that ERBB2 down-regulation plays a crucial role in HNSC pathogenesis and may serve as a potential prognostic biomarker and therapeutic target in this cancer type.
Enhancing Gastrointеstinal (GI) Cancer Therapies with Ganoderma Lucidum: A Review of Mechanisms and Efficacy
Authors: Sharma Kaushal Kishor , Gupta Saksham , Bisen Prakash S. 
Published: January 2025

Gastrointestinal (GI) cancer stands as a global health challenge, necessitating effective therapeutic approaches with minimal adverse еffеct. This review delves into the potential of Ganoderma lucidum, a macro fungus, commonly recognized for its medicinal properties, in traditional Chinese medicine. Macro fungus acts as a promising adjunct for treating gastrointestinal cancer. The bioactive compounds from Ganoderma lucidum are polysaccharides, triterpenes, and proteins demonstrating anti-tumor activities by modulating key cellular mechanisms such as proliferation, apoptosis, metastasis, and autophagy. This review elucidates the mechanisms underpinning G. lucidum's anti-GI cancer properties through an extensive exploration of available literature. Furthermore, it provides understanding of the clinical applications of Ganoderma lucidum, shedding light on its potential as a complementary therapeutic option in the realm of both traditional Chinese and western medicine. The comprehensive analysis presented herein aims to serve as a valuable guide for future studies endeavors, fostering a dееpеr understanding of G. lucidum’s role in both preventing and treating GI cancer.
Noncoding RNAs: Key Modulators of the Hippo Pathway in Hepatocellular Carcinoma Progression
Authors: Sadri Farzad , Rezaei Zohreh 
Published: January 2025

The Hippo signaling system plays a vital role in controlling cell proliferation, apoptosis, and organ size. Disruption of this pathway strongly correlates with the growth and progression of hepatocellular carcinoma (HCC). Noncoding RNAs (ncRNAs), including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), play a crucial role in regulating Hippo signaling and have a significant impact on different aspects of liver tumor development. This paper thoroughly investigates the functions of ncRNAs in regulating the Hippo pathway, specifically in liver cancer. We examine how certain miRNAs and lncRNAs engage with Hippo signaling components, influencing cellular processes like growth regulation, programmed cell death, the spread of cancer cells, and resistance to chemotherapy. Developing an understanding of these interactions offers valuable knowledge about the intricate regulatory networks that control liver cancer and identifies possible targets for therapeutic intervention. Our study shows how important it is for ncRNA to control Hippo signaling in liver cancer. It also suggests possible directions for future research that focuses on creating ncRNA-based diagnostic and therapeutic methods.
Smallholder's Readiness to Adopt Platforms Linking Local Resource-Sharing in Egypt
Authors: Mansour Tamer Gamal Ibrahim , Pham Congduc , Lionboui Hayat , Fouad Zakaria , El-Gamal Seham Mohamed Abd El Hameed 
Published: January 2025

Digital technology in developing countries improves agriculture with knowledge and experience. Digital platforms can link local resource-sharing networks to connect agricultural sectors, especially in emergencies. Hence, this paper assessed smallholders' readiness to adopt platforms facilitating local link resource-sharing in Egypt. This was achieved by assessing the existing options for resource sharing and identifying the factors that influence this sharing, evaluating the respondents' understanding of information and communication technology (ICT) identifying their sources of information about these tools, and determining the reasons behind the respondents' use of digital platforms. A structured questionnaire was administered to 128 selected farmers from Beni Suef Governorate in Egypt. The results showed that work (65.5%) and agricultural operations (irrigation-fertilization-harvesting) (62.5%) were the most important present possibilities for sharing resources. As were their agricultural uses, ICTs and the Internet of Things (IoT) were unfamiliar to 53.88% of respondents. Using information digital platforms in agriculture was crucial for finding new markets (84.4%), increasing productivity (81.25%), and increasing profitability (78.13%). at the same time, 81.25% of respondents cited a lack of awareness about new digital application technologies as a major barrier to embracing digital platforms in agriculture. Thus, the study recommends the importance of moving forward toward establishing the RESILIENCE platform with farmers and considering their participation at every project stage.
MENUMBUHKAN SIKAP KEWIRAUSAHAAN SEJAK USIA DINI
Authors: Melda Darys Pesona  , Nuru Annissa  , Puput Prila Santika  
Published: January 2025

Entrepreneurship education must start from an early age. It is during this period that the role of parents is very necessary in shaping their life patterns, namely by instilling religious moral values, motivating them to study diligently and also using methods through play and reflection so that they hope that when they are adults they can become good people. who will be successful in the future. For this reason, the role of the father as head of the family must be able to support the role of the mother whose main task is to care for and educate children so that an entrepreneurial spirit can be fostered from an early age. The family plays a very big role in instilling an entrepreneurial spirit from an early age by involving the cooperation of both parents. The aim of this research is to describe what entrepreneurial skills should be given to children from an early age and to find out how children learn entrepreneurship. This research method is a literature study method. The results of collecting journals related to the title are entrepreneurial skills that can be introduced from an early age, namely the ability to do business based on their interests and hobbies. Children are able to learn business if parents guide children to think about how manage the business/business in a planned manner. Teachers and parents always act as facilitators so that they can note children's interests and talents.
STRATEGI INDUSTRI MANUFAKTUR DALAM MENINGKATKAN PERCEPATAN PERTUMBUHAN EKONOMI DI INDONESIA
Authors: Ravellino Dwi Cahya  , Muhammad Yasin  
Published: January 2025

Indonesia is a developing country and the economic development activities carried out aim to reduce existing economic problems. This is done through industrialization. Manufacturing Industry almost always gets the main priority in a developing country's development plans. Important challenges facing the Indonesian manufacturing industry sector include the possibility of disparities in the level of efficiency and productivity of each sub-sector of the Indonesian manufacturing industry. Industrialization is one thing that can encourage GRDP and economic development. However, industrialization carried out in several regions has not been able to provide high, stable and sustainable economic growth as well as high economic resilience against various threats. The aim of this research is to find out more effective industrialization strategies in the economic structure in Indonesia. This research uses qualitative methods with a library research approach. The results of this research are that the manufacturing industry strategy in increasing the acceleration of Indonesia's economic growth is carried out by implementing industrial strategy 4.0. With support in the form of a systematic and well-integrated Industry 4.0 development platform for a unified ecosystem, it is hoped that collaboration can be created between stakeholders so that joint technical standards/platforms can be developed so that a domestic market that is competitive and independent can be created.
ANALISIS CR, DAR, DER, NPM, ROA DAN ROE TERHADAP PERTUMBUHAN LABA PERIODE TRIWULAN DARI TAHUN 2016-2022 ((Studi Pada PT Telekomunikasi Indonesia Yang Terdaftar Di BEI))
Authors: Febrianti Dian , Wuryanti Lestari , Indriani Wiewiek 
Published: January 2025

Profit growth is an increase in company profits compared to previous period earnings Good company profit growth reflects that the condition of the company's performance is also good, if the economic conditions are good the company's growth is generally good. Because profit is a measure of the performance of a company, the higher the profit achieved by the company, indicates the better the company's performance, thus investors are interested in investing their capital. ZThe object in this study is PT Telekomunikasi Indonesia Tbk which is listed on the IDX for the Quarterly Period from 2016-2022. The sampling method in this study used nonprobabilin sampling with purposive sampling. The results of this study stated that partially the CR variable had a significant negative effect on profit growth, while the DAR, DER NPM, ROA and ROE variables partially had no effect on profit growth simultaneously with the CR variable. DAR DER NPM ROA and ROE affect profit growth at PT Telekomunikasi Indonesia Tbk which is listed on the IDX Quarterly period from 2016/2022
PERSEPSI PUBLIK TERHADAP KINERJA KEPOLISIAN DI KOTA MAGELANG
Authors: Reanisane Zindy , Cahyati Hanifah Nur , Adawiyah Siti Robbiatul , Dwi Arjun Muhammad , Setiawan Andika Aranda , Nugraha Joko Tri 
Published: January 2025

Persepsi publik memainkan peran penting dalam membangun kepercayaan dan hubungan yang efektif antara aparat kepolisian dan masyarakat. Penelitian ini bertujuan untuk menganalisis persepsi publik terhadap kinerja kepolisian di Kota Magelang. Penelitian dilakukan pada bulan Oktober 2024 dengan melibatkan 125 orang masyarakat dengan rentang usia antara 17- 50 tahun dengan jenis pekerjaan yang beragam di Kota Magelang sebagai responden penelitian. Teknik pengambilan sampelnya adalah random sampling. Data penelitian ini dikumpulkan dengan instrumen kuesioner tentang persepsi yang berjumlah 10 item dan instrumen kepercayaan yang berjumlah 21 item. Hasil penelitian menunjukkan bahwa kinerja polisi di Kota Magelang cukup baik menurut masyarakat. Persepsi berpengaruh secara positif terhadap kepercayaan diri. Hasil penelitian ini diharapkan dapat memberikan wawasan bagi pihak kepolisian untuk meningkatkan strategi pelayanan dan memperkuat hubungan dengan masyarakat, serta menjadi referensi bagi studi-studi serupa di masa mendatang.

Kata kunci: Persepsi, Kepercayaan, Kinerja
PERSEPSI MASYARAKAT PADA MAKNA EKSPRESI WAJAH DAN GESTUR TUBUH DALAM BERKOMUNIKASI
Authors: Mulan Syawalia Dwiayu , Maylani Ayu , Ferdyan Marcello Hugo , Halim Muhammad Irfan , Tri Nugraha Joko 
Published: January 2025

Penelitian ini bertujuan untuk mengetahui persepsi masyarakat pada makna ekspresi wajah dan gestur tubuh dalam berkomunikasi. Keterampilan komunikasi yang efektif sangat penting dalam berbagai aspek kehidupan, baik di lingkungan kerja, akademis, maupun sosial. Salah satu komponen utama dari komunikasi yang efektif adalah kemampuan untuk memperhatikan dan menafsirkan Bahasa tubuh serta Ekspresi wajah. Penelitian ini menggunakan metode kuantitatif dengan pendekatan survei, dimana data primer diperoleh melalui penyebaran kuesioner. Responden dalam penelitian ini adalah seluruh elemen masyarakat baik dari kalangan muda sampai dewasa. Hasil penelitian menunjukkan bahwa sebagian besar persepsi masyarakat pada makna ekspresi wajah ataupun gestur tubuh sangat penting dan krusial apabila kedua-duanya dikombinasikan dalam komunikasi sehari-hari sebagai penegas kata-kata verbal. Senyum yang tulus dan kontak mata yang konsisten adalah indikator utama yang digunakan oleh masyarakat untuk menilai kepercayaan. Gestur tangan yang juga berkontribusi positif terhadap persepsi kepercayaan. Bahasa tubuh dan ekspresi wajah dapat meningkatkan kemampuan seseorang untuk berkomunikasi dengan lebih jelas dan efektif, mengurangi potensi kesalahpahaman, dan membangun hubungan yang lebih baik.
Kata Kunci: Bahasa Tubuh, Ekspresi Wajah, dan Komunikasi
PERSPEKTIF EKONOMI ISLAM TERHADAP USAHA KERAJINAN TAPIS DALAM MENINGKATKAN EKONOMI KELUARGA (Studi Di Kelurahan Uemalingku Kec. Ratolindo Kab. Tojo Una-Una)
Authors: Mardiyanti Titi , Bahria Khaerul 
Published: January 2025

Penelitian ini membahasa tentang “Prespektif Ekonomi Islam Terhadap Usaha Kerajinan Tangan Dalam Meningkatkan Ekonomi keluarga” ini merupakan penelitian lapangan (field research). Pada Pelaku Usaha Kerajinan Tapis Rumahan. Adapun rumusan masalah dalam penelitian ini adalah : (1). Bagaimana cara meningkatkan usaha kerajinan Tapis di Kelurahan Uemalingku Kec. Ratolindo Kab. Tojo Una-Una dan (2). Bagaimana perspektif ekonomi Islam terhadap usaha kerajinan Tapis dalam meningkatkan ekonomi keluarga. Penelitian ini menggunakan jenis penelitian deskriptif dengan pendekatan kualitatif. Sumber data yang diperoleh dari data primer (secara langsung) adalah hasil penelitian lapangan yaitu wawancara para usaha pengrajin Tapis rumahan mengenai usaha kerajinan Tapis. Adapun metode pengumpulan data yang dipakai yaitu dengan wawancara,observasidan dokumentasi. Sedangkan teknik analisis data yang digunakan dalam penelitian ini adalah reduksi data, penyajian data, dan verifikasi data. Hasil penelitian di ketahui bahwa, bahwa melalui kegiatan usaha kerajinan tapis yang dijalankan oleh masyarakat Kelurahan Uemalingku Kec. Ratolindo Kab. Tojo Una-Una telah memberikan dampak peningkatan pendapatan/perekononiam dalam rumah tangga mereka, dari terpenuhinya kebutuhan keluarga sampai dengan terbukanya lapangan pekerjaan bagi masyarakat setempat. Adapun dari prespektif ekonomi islam terhadap usaha tapis adalah usaha tapis tersebut tidak melanggar dari syariat Islam, baik dari cara penjualan dengan sistem pemesanan yang jelas dengan harga yang sesuai dan dari bahan pembuatan tapis tersebut diperoleh secara baik dan halal yang tidak merusak alam sekitar
ANALISIS PUISI KABAR DARI LAUT KARYA CHAIRIL ANWAR MENGGUNAKAN PENDEKATAN OBJEKTIIF
Authors: Pratiwi Ellisya 
Published: January 2025

Penelitian ini bertujuan untuk menganalisis puisi Kabar Dari Laut karya Chairil Anwar dengan menggunakan pendekatan objektif yang menitikberatkan pada unsur-unsur esensial seperti struktur fisik dan struktur batin puisi. Pendekatan ini memandang puisi sebagai karya yang mandiri, tanpa menghubungkannya dengan aspek eksternal seperti latar belakang kehidupan penyair atau konteks sosial. Penelitian ini menggunakan metode deskriptif kualitatif dengan teknik pengumpulan data berupa penelitian kearsipan. Analisis struktur fisik meliputi diksi, citraan, gaya bahasa, bunyi, irama, dan rima. Analisis struktur batin di sisi lain, mencakup tema, nada, rasa dan amanat. Penelitian menemukan bahwa puisi tersebut mengandung tema-tema utama tentang perjalanan emosional seorang pria saat ia menghadapi rasa sakit karena putus cinta dan mencoba menemukan kembali identitasnya. Simbolisme laut merupakan elemen sentral puisi ini, mewakili ketidakpastian, disorientasi, dan kecemasan batin. Pilihan kata yang sederhana namun bermakna, gambaran yang kaya, dan elemen struktur fisik seperti metafora dan personifikasi menciptakan suasana yang sangat melankolis.
Kata Kunci : Puisi, Analisis, Simbolisme
THE INFLUENCE OF SOCIAL MEDIA ON ADOLESCENT MENTAL HEALTH: A LITERATURE REVIEW
Authors: Anissa Mutiara , Lovprima Nopeliantesa , Septiani Vadila , Abdullah Dessy , Hasni Dita 
Published: January 2025

Introduction/ Background: Based on WHO data, as many as 10-20% of children and adolescents in the world experience mental health problems. It is estimated that 50% of mental disorders occur by the age of 14 and 75% by the age of 18. The most common disorders in children and adolescents are generalized anxiety disorder and depression. Social media users in Indonesia reach 150 million (56%) of the total population. In Indonesia, teenagers are the most popular social media users. The impact received from the influence of social media is the disruption of mental health, such as depression caused by cyberbullying. Objective: This study aims to analyze social media's influence on adolescent mental health—method: Method used in the narrative review with PRISMA 2020. The literature search in this literature review uses two databases: Google Scholar and ScienceDirect. The critical words of the Indonesian Language are the influence of social media and adolescent mental health. English keywords are social media influence and adolescent mental health. Results: The results of a study from 11 journals found that mental health problems owned by adolescents who use social media include emotional mental disorders, abnormal emotional symptoms, abnormal behavior problems, abnormal hyperactivity, and abnormal peer problems. Adolescent mental health problems mainly occur in adolescent girls. Based on the results of all studies, social media influences mental health problems experienced by adolescents. Conclusion: Social media is used by almost everyone in this world today. The majority of social media use is by teenagers. Social media hurts adolescent mental health. Teenagers must use social media wisely.
THE RELATIONSHIP OF PSYCHOSOCIAL STRESS WITH MENTAL EMOTIONAL STATUS ON STUDENTS OF SENIOR HIGH SCHOOL I IN PADANG
Authors: Putri Zulkifli Tania , Anissa Mutiara , Darmayanti Anita 
Published: January 2025

Stres merupakan kondisi individu mengalami tekanan yang dipicu beberapa faktor sehingga menimbulkan penolakan diri untuk menerimanya. Pemicu stres disebut dengan stressor. Segala fenomena dalam lingkungan dapat mengakibatkan terganggunya keseimbangan mental individu disebut dengan stressor psikososial. Mental emosional adalah suatu usaha menyesuaikan diri dengan lingkungan. Perubahan emosional berlanjut berkembang menjadi keadaan patologis menyebabkan seseorang mengalami gangguan mental emosional. Penelitian bertujuan untuk mengetahui hubungan tingkat stres psikososial dengan status mental emosional pada siswa salah satu Sekolah Menengah Atas Negeri (SMAN) di kota Padang. Penelitian dilakukan pada bulan Mei-November 2022. Jenis penelitian cross-sectional. Populasi terjangkau pada penelitian adalah siswa SMAN 1 Padang sebanyak 198 sampel dengan teknik proporsionate stratified random sampling. Analisa data menggunakan uji chi-square. Pada penelitian diperoleh tingkat terbanyak yang dialami responden stres ringan (26,3%), keaadaan tempat tinggal merupakan jenis stresor terbanyak (69,7%), status mental emosional sebagian besar terganggu, 64,6%), dan ada hubungan tingkat stres psikososial dengan status mental emosional pada siswa SMAN 1 Padang
Cosmology, Gender, and Rituals: An Analysis of the Nuosu Shalaluo Ceremony
Authors: Jike Lili 
Published: January 2025

The Shalaluo ceremony, a coming-of-age ritual in Nuosu society, represents a critical transition for girls into adulthood. This study examines the ceremony’s sociocultural and spiritual significance by situating it within the broader framework of the Jia zhi system, ancestral worship, and gendered expectations. Through its symbolic processes—such as the five-section skirt and ancestral blessings—the Shalaluo reinforces the Nuosu cosmology’s emphasis on lineage continuity, moral purity, and spiritual legitimacy. Moreover, the role of elderly women as ritual facilitators highlights their unique position as cultural custodians who transmit tradition while upholding patriarchal norms. This paper argues that the Shalaluo ceremony not only reflects the societal and spiritual pressures placed on women but also reveals the interconnectedness of family, cosmology, and identity in Nuosu culture.