bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flow Diverter Treatment of Ruptured Basilar Artery Perforator Aneurysms
Authors: Elsheikh Samer , Möhlenbruch Markus , Seker Fatih , Berlis Ansgar , Maurer Christoph , Kocer Naci , Jamous Ala , Behme Daniel , Taschner Christian , Urbach Horst , Meckel Stephan 
Published: January 2022

Abstract
Purpose
Ruptured basilar artery perforator aneurysms (BAPAs) represent a very rare cause of subarachnoid hemorrhage and an under-reported subtype of cerebral aneurysm. There is no consensus for the optimal treatment strategy (conservative vs. surgical vs. various endovascular approaches). We aim to present a multicenter experience of BAPA treatment using flow-diverter (FD) stents.

Methods
At five tertiary neurovascular centers, all cases of ruptured BAPAs treated by FD were retrospectively collected. Baseline imaging and clinical characteristics, complications, as well as early and long-term angiographic and clinical outcome (mRS) were analyzed.

Results
Eighteen patients (mean age, 57 years; SD, ±10.7 years) with acute SAH related to a BAPA were treated using 18 FD stents. Aneurysms were detected on initial imaging study in 28%; delayed diagnosis was triggered by clinical deterioration due to rebleeding in 15%. No rebleeding after FD was seen, 28% developed FD-related ischemic complications. At long term (n = 16), overall mortality was 13% (2/16), and favorable outcome (mRS 0–2) was 81% (13/16). All BAPAs (n = 13) were completely occluded at long-term angiographic follow-up.

Conclusion
In our multicenter experience, FD treatment of ruptured BAPAs appears to have comparable safety and efficacy outcomes to FD treatment of other ruptured posterior circulation aneurysms as well as to the conservative management of BAPAs. This treatment strategy for a ruptured BAPA achieved a high rate of angiographic occlusion and favorable clinical outcome; however, as the conservative management also seems to offer similar clinical outcomes an individualized treatment decision is warranted. Future prospective studies comparing both approaches are required.
Development and Standardization of Testing Equipment and Methods for Spacer Fabrics
Authors: Schwager Carolin , Peiner Christoph , Bettermann Isa , Gries Thomas 
Published: January 2022

AbstractSpacer fabrics are three-dimensional textile structures consisting of two textile cover surfaces and a spacer thread. Up to now, spacer fabrics have been tested according to standards for flat textiles or other non-textile materials. However, these standards do not take into account the special requirements for testing spacer fabrics. Some sample holders of the testing devices are not designed for the thickness of the spacer fabrics, so that the tests cannot be carried out. In other tests, the samples can be mounted, but the test results are falsified by the methodology, e.g. strong compression of the sample before testing. Therefore, objective comparisons among spacer fabrics or between spacer fabrics and conventional flat textiles or non-textile materials cannot be made in all areas of application. The focus of this paper is in the developing of testing devices for seven test setups (1. sample preparation, 2. maximum force, 3. thickness, 4. compression, 5. mass per unit area, 6. permeability to air, 7. abrasion resistance). The new testing devices and methods were designed and manufactured using the method of an iterative development process. The following steps were carried out identically for all seven test setups: deficit analysis, development of concepts, construction of test benches, evaluation, transfer into standards. As part of this research work the developed devices where both tested and evaluated by industrial partners as well as later translated into a standard by the German Institute for Standardization (DIN e.V.). As a central result, a first standard for the testing of spacer fabrics was created and published: DIN 60022–1 “Spacer textiles – Terms and definitions, sample preparation” [4]. For testing textiles, it is important that geometrically identical and structurally intact samples are prepared. Therefore, this standard provides measurement tools and methods for the evaluation of sample quality (e.g. roundness of circular samples, maximum offset and shearing of the surfaces). Two further test methods (determination of thickness and air permeability) were developed and are now being transferred to standards. Within the new test standards, the special properties of spacer fabrics are given special consideration. In addition to the test methods developed within this work, further research is necessary. In particular, the tilting stability (linked to the in-plane and out-of-plane shear measurement) as well as the compression behaviour of spacer fabrics are important tests that need to be analysed and further developed. Therefore, further research is planned for six test methods (1. compression hardness, 2. compression set, 3. tilting stability, 4. pressure point distribution, 5. abrasion resistance, 6. maximum force). This work enables standardized testing of spacer fabrics and thus objective comparisons not only between various spacer fabric constructions but also with conventional flat textiles and with non-textile materials.
Epistemic uncertainty of probabilistic building exposure compositions in scenario-based earthquake loss models
Authors: Gómez Zapata Juan Camilo , Pittore Massimiliano , Cotton Fabrice , Lilienkamp Henning , Shinde Simantini , Aguirre Paula , Santa María Hernán 
Published: January 2022

AbstractIn seismic risk assessment, the sources of uncertainty associated with building exposure modelling have not received as much attention as other components related to hazard and vulnerability. Conventional practices such as assuming absolute portfolio compositions (i.e., proportions per building class) from expert-based assumptions over aggregated data crudely disregard the contribution of uncertainty of the exposure upon earthquake loss models. In this work, we introduce the concept that the degree of knowledge of a building stock can be described within a Bayesian probabilistic approach that integrates both expert-based prior distributions and data collection on individual buildings. We investigate the impact of the epistemic uncertainty in the portfolio composition on scenario-based earthquake loss models through an exposure-oriented logic tree arrangement based on synthetic building portfolios. For illustrative purposes, we consider the residential building stock of Valparaíso (Chile) subjected to seismic ground-shaking from one subduction earthquake. We have found that building class reconnaissance, either from prior assumptions by desktop studies with aggregated data (top–down approach), or from building-by-building data collection (bottom–up approach), plays a fundamental role in the statistical modelling of exposure. To model the vulnerability of such a heterogeneous building stock, we require that their associated set of structural fragility functions handle multiple spectral periods. Thereby, we also discuss the relevance and specific uncertainty upon generating either uncorrelated or spatially cross-correlated ground motion fields within this framework. We successively show how various epistemic uncertainties embedded within these probabilistic exposure models are differently propagated throughout the computed direct financial losses. This work calls for further efforts to redesign desktop exposure studies, while also highlighting the importance of exposure data collection with standardized and iterative approaches.
Nociceptive Intra-epidermal Electric Stimulation Evokes Steady-State Responses in the Secondary Somatosensory Cortex
Authors: van den Berg Boudewijn , Manoochehri Mana , Schouten Alfred C. , van der Helm Frans C. T. , Buitenweg Jan R. 
Published: January 2022

AbstractRecent studies have established the presence of nociceptive steady-state evoked potentials (SSEPs), generated in response to thermal or intra-epidermal electric stimuli. This study explores cortical sources and generation mechanisms of nociceptive SSEPs in response to intra-epidermal electric stimuli. Our method was to stimulate healthy volunteers (n = 22, all men) with 100 intra-epidermal pulse sequences. Each sequence had a duration of 8.5 s, and consisted of pulses with a pulse rate between 20 and 200 Hz, which was frequency modulated with a multisine waveform of 3, 7 and 13 Hz (n = 10, 1 excluded) or 3 and 7 Hz (n = 12, 1 excluded). As a result, evoked potentials in response to stimulation onset and contralateral SSEPs at 3 and 7 Hz were observed. The SSEPs at 3 and 7 Hz had an average time delay of 137 ms and 143 ms respectively. The evoked potential in response to stimulation onset had a contralateral minimum (N1) at 115 ms and a central maximum (P2) at 300 ms. Sources for the multisine SSEP at 3 and 7 Hz were found through beamforming near the primary and secondary somatosensory cortex. Sources for the N1 were found near the primary and secondary somatosensory cortex. Sources for the N2-P2 were found near the supplementary motor area. Harmonic and intermodulation frequencies in the SSEP power spectrum remained below a detectable level and no evidence for nonlinearity of nociceptive processing, i.e. processing of peripheral firing rate into cortical evoked potentials, was found.
Simulation of flow in deformable fractures using a quasi-Newton based partitioned coupling approach
Authors: Schmidt Patrick , Jaust Alexander , Steeb Holger , Schulte Miriam 
Published: January 2022

AbstractWe introduce a partitioned coupling approach for iterative coupling of flow processes in deformable fractures embedded in a poro-elastic medium that is enhanced by interface quasi-Newton (IQN) methods. In this scope, a unique computational decomposition into a fracture flow and a poro-elastic domain is developed, where communication and numerical coupling of the individual solvers are realized by consulting the open-source library preCICE. The underlying physical problem is introduced by a brief derivation of the governing equations and interface conditions of fracture flow and poro-elastic domain followed by a detailed discussion of the partitioned coupling scheme. We evaluate the proposed implementation and undertake a convergence study to compare a classical interface quasi-Newton inverse least-squares (IQN-ILS) with the more advanced interface quasi-Newton inverse multi-vector Jacobian (IQN-IMVJ) method. These coupling approaches are verified for an academic test case before the generality of the proposed strategy is demonstrated by simulations of two complex fracture networks. In contrast to the development of specific solvers, we promote the simplicity and computational efficiency of the proposed partitioned coupling approach using preCICE and FEniCS for parallel computations of hydro-mechanical processes in complex, three-dimensional fracture networks.
Analysing app reviews for software engineering: a systematic literature review
Authors: Dąbrowski Jacek , Letier Emmanuel , Perini Anna , Susi Angelo 
Published: January 2022

AbstractApp reviews found in app stores can provide critically valuable information to help software engineers understand user requirements and to design, debug, and evolve software products. Over the last ten years, a vast amount of research has been produced to study what useful information might be found in app reviews, and how to mine and organise such information as efficiently as possible. This paper presents a comprehensive survey of this research, covering 182 papers published between 2012 and 2020. This survey classifies app review analysis not only in terms of mined information and applied data mining techniques but also, and most importantly, in terms of supported software engineering activities. The survey also reports on the quality and results of empirical evaluation of existing techniques and identifies important avenues for further research. This survey can be of interest to researchers and commercial organisations developing app review analysis techniques and to software engineers considering to use app review analysis.
Reimagining Gender Through Equality Law: What Legal Thoughtways Do Religion and Disability Offer?
Authors: Renz Flora , Cooper Davina 
Published: January 2022

AbstractBritish equality law protections for sex and gender reassignment have grown fraught as activists tussle over legal and social categories of gender, gender transitioning, and sex. This article considers the future of gender-related equality protections in relation to ‘decertification’—an imagined reform that would detach sex and gender from legal personhood. One criticism of decertification is that de-formalising gender membership would undermine equality law protections. This article explores how gender-based equality law could operate in conditions of decertification, drawing on legal thoughtways developed for two other protected characteristics in equality law—religion and belief, and disability—to explore the legal responses and imaginaries that these two grounds make available. Religious equality law focuses on beliefs, communities, and practices, deemed to be stable, multivarious, and subject to deep personal commitment. Disability equality law focuses on embodied disadvantage, approached as social, relational, and fluctuating. While these two equality frameworks have considerable limitations, they offer legal thoughtways for gender oriented to both its hierarchies and its expression, including as disavowal.
Parent Activation Measure for Developmental Disabilities (PAM-DD) in Caregivers of Individuals With ASD
Authors: Yu Yue , Ruble Lisa , McGrew John , Murray Donna 
Published: January 2022

AbstractActivation refers to patients’ belief, knowledge, ability, and persistence to manage care. The concept is adapted to parent activation in developmental disorders. This study examined the psychometrics of the Parent Activation Measure for Developmental Disabilities (PAM-DD) and factors related to parent activation in ASD. Data from 658 caregivers of children with ASD in the Autism Treatment Network Registry Call Back Assessment study were analyzed. The actual ordering of the scale items was inconsistent with the assumptions of a Guttman scaling. Factor analysis revealed two PAM-DD factors. Lower child symptom severity was related to higher Factor 1 and lower Factor 2 activation. Future studies should use caution when treating PAM-DD as a Guttman and unidimensional scale.
Usability of the SedLine® electroencephalographic monitor of depth of anaesthesia in pigs: a pilot study
Authors: Mirra A. , Casoni D. , Barge P. , Hight D. , Levionnois O. , Spadavecchia C. 
Published: January 2022

AbstractTo investigate the usability of the SedLine® monitor in anaesthetized pigs. Five juvenile healthy pigs underwent balanced isoflurane-based general anaesthesia for surgical placement of a subcutaneous jugular venous port. The SedLine® was applied to continuously monitor electroencephalographic (EEG) activity and its modulation during anaesthesia. Computer tomography and magnetic resonance were performed to investigate the relationship between electrodes’ positioning and anatomical structures. The pediatric SedLine® EEG-sensor could be easily applied and SedLine®-generated variables collected. An EEG Density Spectral Array (DS) was displayed over the whole procedure. During surgery, the EEG signal was dominated by elevated power in the delta range (0.5–4 Hz), with an underlying broadband signal (where power decreased with increasing frequency). The emergence period was marked by a decrease in delta power, and a more evenly distributed power over the 4–40 Hz frequency range. From incision to end of surgery, mean SedLine®-generated values (± standard deviation) were overall stable [23.0 (± 2.8) Patient State Index (PSI), 1.0% (± 3.8%) Suppression Ratio (SR), 8.8 Hz (± 2.5 Hz) Spectral Edge Frequency 95% (SEF) left, 7.7 Hz (± 2.4 Hz) SEF right], quickly changing during emergence [75.3 (± 11.1) PSI, 0.0 (± 0.0) SR, 12.5 (± 6.6) SEF left 10.4 (± 6.6) SEF right]. Based on the imaging performed, the sensor does not record EEG signals from the same brain areas as in humans. SedLine®-DSA and -generated variables seemed to reflect variations in depth of anaesthesia in pigs. Further studies are needed to investigate this correlation, as well as to define the species-specific brain structures monitored by the EEG-sensor.
Energy efficiency optimization in adaptive massive MIMO networks for 5G applications using genetic algorithm
Authors: Salah Ibrahim , Mabrook M. Mourad , Rahouma Kamel Hussein , Hussein Aziza I. 
Published: January 2022

AbstractGiven that, the exponential pace of growth in wireless traffic has continued for more than a century, wireless communication is one of the most influential innovations in recent years. Massive Multiple-Input Multiple-Output (M-MIMO) is a promising technology for meeting the world's exponential growth in mobile data traffic, particularly in 5G networks. The most critical metrics in the massive MIMO scheme are Spectral Efficiency (SE) and Energy Efficiency (EE). For single-cell M-MIMO uplink transmission, energy and spectral-efficiency trade-offs have to be estimated by optimizing the number of base station antennas versus the number of active users. This paper proposes an adaptive optimization technique focusing on maximizing Energy Efficiency at full spectral efficiency using a Genetic Algorithm (GA) optimizer. The number of active antennas is determined according to the change in the number of active users based on the proposed GA scheme that optimizes the EE in the M-MIMO system. Simulation results show that the GA optimization technique achieved the maximum energy efficiency of the 5G M-MIMO platform and the maximum efficiency in the trade-off process.
Study of coliforms and Clostridium bacteria inactivation in wastewaters by a pilot photolysis process and by the maturation lagoons of a low-cost nature-based WWTP
Authors: García-Prieto Juan Carlos , Núñez-Núñez Cynthia Manuela , Proal-Nájera José Bernardo , García-Roig Manuel 
Published: January 2022

AbstractThe inactivation processes of coliform bacteria (total and fecal) and sulphito-reducing Clostridium bacteria (vegetative species and spores) in water maturation lagoon of a low-cost nature-based wastewater treatment plant using constructed wetlands and through processes of photolysis in a pilot photoreactor have been comparatively studied. The different inactivation mechanisms by photolysis of these bacteria have been studied following the criteria of different statistical and kinetic models. Clostridium disinfection treatments fit models in which two types of bacteria populations coexist, one sensitive (vegetative species) and the other (spores) resistant to the treatment, the sensitive one (94%) with an inactivation rate of k = 0.24 ± 0.07 min−1 and the resistant one (6%) with k = 0.11 ± 0.05 min−1. Total coliform photolytic disinfection also shows two populations with different physiological state. The time required to reduce the first logarithmic decimal cycle of the different types of bacteria (physiological states) are δ1 = 4.2 ± 0.9 and δ2 = 8.3 ± 1.1 min, respectively. For fecal coliform photolytic disinfection, only bacteria population, with k = 1.15 ± 0.19 min−1, is found. The results obtained confirm the photolytic disinfection processes and maturation lagoon are effective systems for Clostridia bacteria removal after water treatment by nature-based systems. Total removal of coliform bacteria is not achieved by maturation lagoons, but their reduction is significant using low doses of cumulative radiation.
Democratising Measurement: or Why Thick Concepts Call for Coproduction
Authors: Alexandrova Anna , Fabian Mark 
Published: January 2022

AbstractThick concepts, namely those concepts that describe and evaluate simultaneously, present a challenge to science. Since science does not have a monopoly on value judgments, what is responsible research involving such concepts? Using measurement of wellbeing as an example, we first present the options open to researchers wishing to study phenomena denoted by such concepts. We argue that while it is possible to treat these concepts as technical terms, or to make the relevant value judgment in-house, the responsible thing to do, especially in the context of public policy, is to make this value judgment through a legitimate political process that includes all the stakeholders of this research. We then develop a participatory model of measurement based on the ideal of co-production. To show that this model is feasible and realistic, we illustrate it with a case study of co-production of a concept of thriving conducted by the authors in collaboration with a UK anti-poverty charity Turn2us.
Growth and survival of Bifidobacterium breve and Bifidobacterium longum in various sugar systems with fructooligosaccharide supplementation
Authors: Parhi Priyanka , Song Keang Peng , Choo Wee Sim 
Published: January 2022

AbstractThis study aims to investigate the effect of fructooligosaccharide (FOS) (0.5, 1, 2, 3, and 4%) supplementation on the growth and survival of Bifidobacterium breve and Bifidobacterium longum in glucose, fructose, lactose, and sucrose (2, 3, and 4%) systems with 24-h growth and 10-day survival assays at 37 °C. FOS supplementation showed a higher growth-promoting effect on B. longum than B. breve in various sugar systems. The highest percentage of increase in growth index, 78.5%, was observed with 4% sucrose supplemented with 0.5% FOS in B. longum. In comparison, the highest percentage increase in growth index, 5.6 and 6.6%, was observed in the presence of 2% glucose and 4% lactose supplemented with 0.5% FOS in B. breve. In survival assay, FOS supplementation (0.5–4%) in a 2% lactose system showed the highest positive effect on the cell viability of B. longum on day-10. As for B. breve, FOS supplementation (1 and 2%) in the 2% sucrose system showed the highest positive effect on the cell viability, followed by FOS supplementation (0.5, 3, and 4%) in 2% sucrose and FOS supplementation (3 and 4%) in 2% lactose on day-10. This study demonstrated that the efficacy of FOS supplementation was depended on its concentration, sugar system and its concentration, and Bifidobacterium strain.
Actions of symplectic homeomorphisms/diffeomorphisms on foliations by curves in dimension 2
Authors: ARNAUD MARIE-CLAUDE , ZAVIDOVIQUE MAXIME 
Published: January 2022

AbstractThe two main results in this paper concern the regularity of the invariant foliation of a
$C^0$
-integrable symplectic twist diffeomorphism of the two-dimensional annulus, namely that (i) the generating function of such a foliation is
$C^1$
, and (ii) the foliation is Hölder with exponent
$\tfrac 12$
. We also characterize foliations by graphs that are straightenable via a symplectic homeomorphism and prove that every symplectic homeomorphism that leaves invariant all the leaves of a straightenable foliation has Arnol’d–Liouville coordinates, in which the dynamics restricted to the leaves is conjugate to a rotation. We deduce that every Lipschitz integrable symplectic twist diffeomorphisms of the two-dimensional annulus has Arnol’d–Liouville coordinates and then provide examples of ‘strange’ Lipschitz foliations by smooth curves that cannot be straightened by a symplectic homeomorphism and cannot be invariant by a symplectic twist diffeomorphism.