bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feasibility of a school-based mental health program implementation to improve the status of depression and quality of life of mothers of children with autism spectrum disorders in urban Bangladesh: MENTHOL study
Authors: Naheed Aliya , Islam Md. Saimul , Brooks Meredith B. , Fawzi Mary C. Smith , Ashraf Mir Nabila , Ahmed Helal Uddin , Uddin M. M. Jalal , Koly Kamrun Nahar , Galea Jerome T. , Akhter Shaheen , Nelson Charles , Hossain Saima Wazed , Munir Kerim M. 
Published: March 2022

AbstractBackgroundWe assessed the feasibility of implementing psychological counseling services (PCS) for mothers of children with autism spectrum disorders (ASD) integrated within special education settings in urban Bangladesh.MethodIn two special education schools for ASD in Dhaka City, trained female psychologists screened mothers using the Patient Health Questionnaire (PHQ-9). PCS was administered to all the mothers irrespective of a diagnosis of depression. Mothers with a PHQ-9 score >4 who met criteria for a major depressive episode (MDE) based on the DSM-IV Structured Interview Axis I Disorders (SCID-I) were also administered skill-building training through monthly home visits to support ASD care. The level of depression was assessed by the Depression Measurement Scale (DMS), and quality of life (QoL) was measured by Visual Analogue Scale (VAS) of EQ5D5L scale before and after PCS.ResultAmong 188 mothers enrolled in the study, 81 (43%) received PCS, and 27.1% (22) had MDE. In the first month, 73 sessions were scheduled and 60 completed (85%). In the last month, 53 sessions were scheduled and 52 completed (98%). The mean DMS score decreased from 79.5 ± 23 to 60 ± 20 (p = 0.004), and DMS scores were significantly higher among mothers with MDE (97.8 ± 12.1 v. 69.9 ± 22.1; p < 0.001) compared to those without MDE (72.7 ± 22.6 v. 56.1 ± 18.1; p = 0.003). The mean VAS score improved from 70.3 ± 14.1 to 80.2 ± 13.3 (p = 0.001) between the first and the last session. Changes in DMS were negatively correlated with changes in VAS scores (β: −0.213, 95% CI 0.370 to −0.056).ConclusionWithin special education schools for ASD in urban Bangladesh, it was feasible to administer an integrated program of PCS for mothers of children with ASD by trained psychologists who were able to screen and intervene to reduce their level of depression and improve their quality of life.
Advancing and translating knowledge: a systematic inquiry into the 2010–2020 mental health and psychosocial support intervention research evidence base
Authors: Nemiro Ashley , Jones Theresa , Tulloch Olivia , Snider Leslie 
Published: March 2022

AbstractBackground and study objectivesMHPSS is increasingly seen as a critical component to effective and responsible humanitarian programming. This review examines the extent to which MHPSS research generated since 2010 has contributed to the public health evidence base and how this has influenced and impacted programming and policy in humanitarian settings.MethodsThis mixed-method study included a scoping literature review (n= 50) and a consultation process with qualitative key informant interviews (n= 19) and online survey responses (n= 52) to identify the facilitating and inhibiting factors for the two areas of inquiry and to understand the broader context in which knowledge is generated and taken up. The interviews were thematically analysed and the survey responses were descriptively analysed.ResultsThe review identified a rapidly growing evidence base that has evaluated a range of MHPSS interventions. However, few studies examined long-term impacts of interventions, there was limited direct evidence on outcomes for children and adolescents and whole family approaches, and there were minimal replications of the same approach that could test efficacy across settings and population groups. A general shift was identified in the consultation process away from a focus on disorder towards the more positive aspects of wellbeing. However, there remained a mismatch in many studies included in the literature review, whereby the interventions were broad, community-based but the outcome measures used still focused on changes in symptoms of mental disorders.ConclusionThe evidence base for MHPSS has grown significantly over the last 10 years. However, several knowledge gaps remain, as does the divide between research and practice. Moving forward, MHPSS intervention research needs to be more responsive to the needs on the ground.
Sedigheh Vasmaghi: A new voice of Iranian religious reformism
Authors: Akbar Ali 
Published: March 2022

AbstractThis article explores the ideas of Iranian reformist scholar Sedigheh Vasmaghi and her contribution to religious reformist thought in Iran. As this article demonstrates, a significant aspect of Vasmaghi's work concerns how she understands the extent to which the legal aspects of the Qurʾān and the associated rulings found infiqhliterature are relevant to the conditions of the modern world. This article investigates Vasmaghi's ideas about the Qurʾān and her contextualist approach to interpretation, arguing that her views on Islam's socio-legal rulings are rooted in her approach to the Qurʾān. As the article will demonstrate, Vasmaghi's ideas add to the work of other prominent Iranian reformist scholars such as Abdolkarim Soroush, Muhammad Mujtahed Shabestari, Mohsen Kadivar and Hassan Yousefi Eshkevari, but her approach is also subject to criticism, in particular her manner of differentiating between the mutable and immutable aspects of religion.
Is the neuroscientist's grandmother in the notebook? Integrated information and reference frames in the search for consciousness
Authors: Riva Giuseppe 
Published: March 2022

AbstractThis commentary suggests that the physical substrate of integrated information is dependent on the reference frame used to observe it. Furthermore, it uses a thought experiment – can a neuroscientist, locked in a closed room and connected through Zoom with his grandmother to demonstrate that the consciousness of his grannie is NOT in the PC? – to underline the problems that neglecting reference frames may cause to consciousness research.
Measures of differentiation and integration: One step closer to consciousness
Authors: Massimini Marcello , Sarasso Simone , Casarotto Silvia , Rosanova Mario 
Published: March 2022

AbstractInterpreting empirical measures of integration and differentiation as indices of cortical performance and memory consolidation during wakefulness rather than consciousness per se is inconsistent with the literature. Recent studies show that these theory-inspired measures can dissociate from such processes and reliably index the brain's capacity for experience. We consider this as a positive trend in consciousness research.
“It's All for the Child”: The Discontents of Middle-class Chinese Parenting and Migration to Europe
Authors: Beck Fanni , Nyíri Pál 
Published: March 2022

AbstractMiddle-class parents in China are increasingly torn between the need to secure their child's future in an environment where competition starts in kindergarten and parenting ideologies focusing on the child's individuality, creativity and freedom. Our study, based on ethnographic fieldwork among middle-class Chinese migrants in Budapest, shows that one result of this tension is a new wave of emigration that is justified in terms of securing a relaxed, healthy and free environment for the child. These migrants consciously reject what they see as a materialistic and dehumanizing social environment in China and pursue a “European” lifestyle that they imagine as wholesome and human-centred; yet while they rejoice in the “happiness” of their children, they retain a deep-seated anxiety about their children's future. Thus, the search for a mentally and physically wholesome environment consonant with China's discourse of national revitalization becomes decoupled from its original agenda and triggers a new trend in international mobility. This study illustrates how the broader tensions in the relationship between China's middle class and the state are externalized to the global stage.
TopoTEM: A Python Package for Quantifying and Visualizing Scanning Transmission Electron Microscopy Data of Polar Topologies
Authors: O'Connell Eoghan N , Moore Kalani , McFall Elora , Hennessy Michael , Moynihan Eoin , Bangert Ursel , Conroy Michele 
Published: March 2022

Abstract
The exotic internal structure of polar topologies in multiferroic materials offers a rich landscape for materials science research. As the spatial scale of these entities is often subatomic in nature, aberration-corrected transmission electron microscopy (TEM) is the ideal characterization technique. Software to quantify and visualize the slight shifts in atomic placement within unit cells is of paramount importance due to the now routine acquisition of images at such resolution. In the previous ~decade since the commercialization of aberration-corrected TEM, many research groups have written their own code to visualize these polar entities. More recently, open-access Python packages have been developed for the purpose of TEM atomic position quantification. Building on these packages, we introduce the TEMUL Toolkit: a Python package for analysis and visualization of atomic resolution images. Here, we focus specifically on the TopoTEM module of the toolkit where we show an easy to follow, streamlined version of calculating the atomic displacements relative to the surrounding lattice and thus plotting polarization. We hope this toolkit will benefit the rapidly expanding field of topology-based nano-electronic and quantum materials research, and we invite the electron microscopy community to contribute to this open-access project.
Mapping Water, Energy and Carbon Footprints Along Urban Agglomeration Supply Chains
Authors: Ding Yakui , Li Yongping , Zheng Heran , Ma Yuan , Huang Guohe , Li Yanfeng , Shen Zhenyao 
Published: March 2022

AbstractChina's urban population will increase by 268 million from 2010 to 2030, with the consumption of a large number of resource‐intensive products. Quantitative analysis of the environmental impacts (water, energy and carbon) of urban agglomerations can make trade‐offs among water conservation, energy use, climate change mitigation, and urban development. In this study, a multi‐layer water‐energy‐carbon production path analysis (MWPPA) model is developed for identifying the key final demands, sectors and supply chain paths of the Pearl River Delta urban agglomeration (PUA). Results show that, water, energy and carbon‐emission intensities respectively reduced by 27.3%, 35.6% and 27.6% in 2015, compared to the levels in 2012. More than half of the water‐energy‐carbon (WEC) footprints are export‐driven, where Guangzhou, Shenzhen and Foshan dominate the WEC footprints of PUA. Results also disclose that Shenzhen is the main recipient of water‐energy, while Jiangmen and Huizhou are the main providers of water and energy, respectively. Policy makers are suggested that each industry actively integrate into global value chains in order to leverage its comparative advantage, and Huizhou should take full advantage of its fossil base to form a complete industry chain from the R&D end to the production end around the energy industry.
Anomaly Based Synoptic Analysis and Model Prediction of Six Dust Storms Moving From Mongolia to Northern China in Spring 2021
Authors: Qian Weihong , Leung Jeremy Cheuk‐Hin , Ren Jingjing , Du Jun , Feng Yerong , Zhang Banglin 
Published: March 2022

AbstractSix dust storms that originated from Mongolia and moved to northern China in Spring 2021 are investigated by the anomaly variable‐based analysis method, which is compared to the traditional total‐variable based analysis method. Strong surface wind is a force to form dust storms as commonly known in current practice. However, dust area depicted by total‐wind model product analysis and operational forecast has a large bias to observation even for leading 24 hr. The analysis method of anomaly based variables showed that the domain of an airborne dust storm observed from satellite images is usually located between two neighboring convergence lines of 850 hPa anomalous winds. This connection of dust storm associated with the anomalous wind convergence extends southwestward from an anomalous cyclone and moves from Mongolia to northern China or Northeast China. It is thermodynamically associated with an anomalous thermal contrast, which has a spatial structure of wind, temperature, and geopotential height anomalies in the troposphere. We further found that numerical weather prediction products of the ECMWF model are able to indicate the anomalous wind pattern with lead times of 4–8 days by applying the anomaly based analysis approach. Therefore, this approach can not only depict dust area better but also reveal predictors much easier compared to the traditional total‐variable or full‐field‐based analysis method.
Permafrost Thermal Dynamics and Cryostratigraphy at Villum Research Station, Station Nord, Eastern North Greenland (81°N)
Authors: Strand S. M. , Christiansen H. H. , Gilbert G. L. 
Published: March 2022

AbstractWe provide the northernmost permafrost thermal analysis in Greenland through the ground temperature time series (2014–2021) and cryostratigraphy of two 20‐m deep boreholes (SN1 and SN2) at Villum Research Station, Station Nord (81°N). Three sedimentary units are identified in the stratigraphy: glacial, glaciomarine, and beach deposits. These sandy and gravelly deposits are interpreted to comprise a deglaciation and isostatic emergence sequence. Ice‐poor epigenetic permafrost grew downwards into the deposits following subaerial exposure. Relatively high salinity values (up to 70 ppt) are observed in the glaciomarine unit, resulting in freezing point depressions between 0 and −4°C. The Prinsesse Ingeborg Halvø study area has a polar tundra climate and is unique compared to other high Arctic areas because of a thick (>1 m), long‐lasting snow cover. This snow cover results in relatively high permafrost temperatures for the climate and latitude and the warmest known permafrost north of 80°N. Over the seven‐year study period, average 20 m permafrost temperature was −7.87°C at SN1 and −7.06°C at SN2. The warming rate at 20 m depth was 0.07°C/year at SN1 and 0.05°C/year at SN2, rates which are similar to those of other high Arctic sites. Active layer thickness, extrapolated from the temperature measurements, varied between 0.5 and 1.16 m. The interplay between snow dynamics and seasonal air temperature controls ground thermal regime in the study area. Air temperatures during autumn and midwinter, the fastest warming seasons, influence the ground thermal regime through the gradually developing, dense snowpack.
Inhibition of lung microbiota-derived proapoptotic peptides ameliorates acute exacerbation of pulmonary fibrosis
Authors: D’Alessandro-Gabazza Corina N. , Yasuma Taro , Kobayashi Tetsu , Toda Masaaki , Abdel-Hamid Ahmed M. , Fujimoto Hajime , Hataji Osamu , Nakahara Hiroki , Takeshita Atsuro , Nishihama Kota , Okano Tomohito , Saiki Haruko , Okano Yuko , Tomaru Atsushi , Fridman D’Alessandro Valeria , Shiraishi Miyako , Mizoguchi Akira , Ono Ryoichi , Ohtsuka Junpei , Fukumura Masayuki , Nosaka Tetsuya , Mi Xuenan , Shukla Diwakar , Kataoka Kensuke , Kondoh Yasuhiro , Hirose Masaki , Arai Toru , Inoue Yoshikazu , Yano Yutaka , Mackie Roderick I. , Cann Isaac , Gabazza Esteban C. 
Published: March 2022

AbstractIdiopathic pulmonary fibrosis is an incurable disease of unknown etiology. Acute exacerbation of idiopathic pulmonary fibrosis is associated with high mortality. Excessive apoptosis of lung epithelial cells occurs in pulmonary fibrosis acute exacerbation. We recently identified corisin, a proapoptotic peptide that triggers acute exacerbation of pulmonary fibrosis. Here, we provide insights into the mechanism underlying the processing and release of corisin. Furthermore, we demonstrate that an anticorisin monoclonal antibody ameliorates lung fibrosis by significantly inhibiting acute exacerbation in the human transforming growth factorβ1 model and acute lung injury in the bleomycin model. By investigating the impact of the anticorisin monoclonal antibody in a general model of acute lung injury, we further unravel the potential of corisin to impact such diseases. These results underscore the role of corisin in the pathogenesis of acute exacerbation of pulmonary fibrosis and acute lung injury and provide a novel approach to treating this incurable disease.
Free electrons can induce entanglement between photons
Authors: Baranes Gefen , Ruimy Ron , Gorlach Alexey , Kaminer Ido 
Published: March 2022

AbstractEntanglement of photons is a fundamental feature of quantum mechanics, which stands at the core of quantum technologies such as photonic quantum computing, communication, and sensing. An ongoing challenge in all these is finding an efficient and controllable mechanism to entangle photons. Recent experimental developments in electron microscopy enable to control the quantum interaction between free electrons and light. Here, we show that free electrons can create entanglement and bunching of light. Free electrons can control the second-order coherence of initially independent photonic states, even in spatially separated cavities that cannot directly interact. Free electrons thus provide a type of optical nonlinearity that acts in a nonlocal manner, offering a way of heralding the creation of entanglement. Intriguingly, pre-shaping the electron’s wavefunction provides the knob for tuning the photonic quantum correlations. The concept can be generalized to entangle not only photons but also photonic quasiparticles such as plasmon-polaritons and phonons.
Three-dimensional structured illumination microscopy data of mitochondria and lysosomes in cardiomyoblasts under normal and galactose-adapted conditions
Authors: Opstad Ida S. , Godtliebsen Gustav , Ströhl Florian , Myrmel Truls , Ahluwalia Balpreet Singh , Agarwal Krishna , Birgisdottir Åsa Birna 
Published: March 2022

AbstractThis three-dimensional structured illumination microscopy (3DSIM) dataset was generated to highlight the suitability of 3DSIM to investigate mitochondria-derived vesicles (MDVs) in H9c2 cardiomyoblasts in living or fixed cells. MDVs act as a mitochondria quality control mechanism. The cells were stably expressing the tandem-tag eGFP-mCherry-OMP25-TM (outer mitochondrial membrane) which can be used as a sensor for acidity. A part of the dataset is showing correlative imaging of lysosomes labeled using LysoTracker in fixed and living cells. The cells were cultivated in either normal or glucose-deprived medium containing galactose. The resulting 3DSIM data were of high quality and can be used to undertake a variety of studies. Interestingly, many dynamic tubules derived from mitochondria are visible in the 3DSIM videos under both glucose and galactose-adapted growth conditions. As the raw 3DSIM data, optical parameters, and reconstructed 3DSIM images are provided, the data is especially suitable for use in the development of SIM reconstruction algorithms, bioimage analysis methods, and for biological studies of mitochondria.
Variations in microanatomy of the human modiolus require individualized cochlear implantation
Authors: Pietsch Markus , Schurzig Daniel , Salcher Rolf , Warnecke Athanasia , Erfurt Peter , Lenarz Thomas , Kral Andrej 
Published: March 2022

AbstractCochlear variability is of key importance for the clinical use of cochlear implants, the most successful neuroprosthetic device that is surgically placed into the cochlear scala tympani. Despite extensive literature on human cochlear variability, few information is available on the variability of the modiolar wall. In the present study, we analyzed 108 corrosion casts, 95 clinical cone beam computer tomographies (CTs) and 15 µCTs of human cochleae and observed modiolar variability of similar and larger extent than the lateral wall variability. Lateral wall measures correlated with modiolar wall measures significantly. ~ 49% of the variability had a common cause. Based on these data we developed a model of the modiolar wall variations and related the model to the design of cochlear implants aimed for perimodiolar locations. The data demonstrate that both the insertion limits relevant for lateral wall damage (approximate range of 4–9 mm) as well as the dimensions required for optimal perimodiolar placement of the electrode (the point of release from the straightener; approximate range of 2–5mm) are highly interindividually variable. The data demonstrate that tip fold-overs of preformed implants likely result from the morphology of the modiolus (with radius changing from base to apex), and that optimal cochlear implantation of perimodiolar arrays cannot be guaranteed without an individualized surgical technique.
Characterizing the performance of human leg external force control
Authors: Kudzia Pawel , Robinovich Stephen N. , Donelan J. Maxwell 
Published: March 2022

AbstractOur legs act as our primary contact with the surrounding environment, generating external forces that enable agile motion. To be agile, the nervous system has to control both the magnitude of the force that the feet apply to the ground and the point of application of this force. The purpose of this study was to characterize the performance of the healthy human neuromechanical system in controlling the force-magnitude and position of an externally applied force. To accomplish this, we built an apparatus that immobilized participants but allowed them to exert variable but controlled external forces with a single leg onto a ground embedded force plate. We provided real-time visual feedback of either the leg force-magnitude or force-position that participants were exerting against the force platform and instructed participants to best match their real-time signal to prescribed target step functions. We tested target step functions of a range of sizes and quantified the responsiveness and accuracy of the control. For the control of force-magnitude and for intermediate step sizes of 0.45 bodyweights, we found a bandwidth of 1.8 ± 0.5 Hz, a steady-state error of 2.6 ± 0.9%, and a steady-state variability of 2.7 ± 0.9%. We found similar control performance in terms of responsiveness and accuracy across step sizes and between force-magnitude and position control. Increases in responsiveness correlated with reductions in other measures of control performance, such as a greater magnitude of overshooting. We modelled the observed control performance and found that a second-order model was a good predictor of external leg force control. We discuss how benchmarking force control performance in young healthy humans aids in understanding differences in agility between humans, between humans and other animals, and between humans and engineered systems.