bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative transcriptomic provides novel insights into the soybean response to Colletotrichum truncatum infection
Authors: Boufleur Thaís R. , Massola Júnior Nelson S. , Becerra Sioly , Baraldi Elena , Bibiano Líllian B. J. , Sukno Serenella A. , Thon Michael R. , Baroncelli Riccardo 
Published: November 2022

IntroductionSoybean (Glycine max) is among the most important crops in the world, and its production can be threatened by biotic diseases, such as anthracnose. Soybean anthracnose is a seed-borne disease mainly caused by the hemibiotrophic fungus Colletotrichum truncatum. Typical symptoms are pre- and post-emergence damping off and necrotic lesions on cotyledons, petioles, leaves, and pods. Anthracnose symptoms can appear early in the field, causing major losses to soybean production.Material and MethodsIn preliminary experiments, we observed that the same soybean cultivar can have a range of susceptibility towards different strains of C. truncatum, while the same C. truncatum strain can cause varying levels of disease severity in different soybean cultivars. To gain a better understanding of the molecular mechanisms regulating the early response of different soybean cultivars to different C. truncatum strains, we performed pathogenicity assays to select two soybean cultivars with significantly different susceptibility to two different C. truncatum strains and analyzed their transcriptome profiles at different time points of interaction (0, 12, 48, and 120 h post-inoculation, hpi).Results and DiscussionThe pathogenicity assays showed that the soybean cultivar Gm1 is more resistant to C. truncatum strain 1080, and it is highly susceptible to strain 1059, while cultivar Gm2 shows the opposite behavior. However, if only trivial anthracnose symptoms appeared in the more resistant phenotype (MRP; Gm1-1080; Gm2-1059) upon 120 hpi, in the more susceptible phenotype (MSP; Gm-1059; Gm2- 1080) plants show mild symptoms already at 72 hpi, after which the disease evolved rapidly to severe necrosis and plant death. Interestingly, several genes related to different cellular responses of the plant immune system (pathogen recognition, signaling events, transcriptional reprogramming, and defense-related genes) were commonly modulated at the same time points only in both MRP. The list of differentially expressed genes (DEGs) specific to the more resistant combinations and related to different cellular responses of the plant immune system may shed light on the important host defense pathways against soybean anthracnose.
COVID-19 and mental health: A systematic review of international medical student surveys
Authors: Paz Dean C. , Bains Manav Singh , Zueger Morgan L. , Bandi Varasiddimounish R. , Kuo Victor Y. , Cook Kyle , Ryznar Rebecca 
Published: November 2022

BackgroundThe medical school curriculum has imposed psychological stressors on students worldwide, some of which may induce feelings of increased depression and anxiety. Meanwhile, the COVID-19 pandemic has exacerbated the feelings of stress, depression, and anxiety that a portion of medical students experience in their daily life. The aim of this systematic review is to gather concrete data from medical schools around the globe, and further evaluate how the COVID-19 pandemic has impacted medical students’ mental health.Materials and methodsSystematic search of data from PubMed, EMBASE, psycINFO, MEDLINE Complete, and Global Health for studies conducted between December 2019 and July 2021 was conducted. Data from 47 different surveys of medical students from various medical institutions throughout the world were included in this review. These surveys, administered in the form of questionnaires that utilized rating scales, measured anxiety, depression, and stress levels in medical students amidst the COVID-19 outbreak.ResultsThe COVID-19 outbreak was found to have negative effects on medical students, most notably causing emotional and behavioral changes and detrimental mental health impacts. Higher levels of stress, depression, and anxiety have been found in medical students since the outbreak.ConclusionThis systematic review highlights the sustained high prevalence of moderate depression, anxiety and stress among medical students during the COVID-19 pandemic. Appropriate support and research on which interventions could mitigate these risks is essential in order to ensure that future physicians are properly cared for, and ultimately have the adequate tools needed to provide high quality and empathetic care to future patients.
Trajectories and predictors of social avoidance in female patients with breast cancer
Authors: He Chunyan , Wu Chao , Yang Tianqi , He Yang , Yan Jiaran , Lin Yawei , Du Yanling , He Shizhe , Wu Shengjun , Cao Baohua 
Published: November 2022

BackgroundSocial avoidance plays an important role in influencing quality of life among patients with breast cancer. Social avoidance behaviors change with treatment periods. However, the trajectory patterns and the predictive factors have not been fully studied.ObjectiveThis study examined the growth trajectory of social avoidance and its predictors in patients with breast cancer.Materials and methodsA total of 176 patients with breast cancer in a university hospital in Shaanxi Province, China, were followed up four times over 6 months following surgery, and data from the final 144 patients were analyzed. The growth mixed model (GMM) was used to identify the trajectory categories, and the predictive factors of the trajectory types were analyzed by logistic regression.ResultsThe best-fit growth mixture modeling revealed three class models: persistent high social avoidance group (Class 1), social avoidance increased first and then decreased group (Class 2), and no social avoidance group (Class 3), accounting for 13.89, 31.94, and 54.17% of patients, respectively. Single-factor analysis showed that family income per capita, residence, and temperament type were related to the social avoidance trajectory. Logistic regression analysis showed that only temperament type was an independent predictor of the social avoidance trajectory, and patients with melancholia were more likely to have persistent high social avoidance.ConclusionOur study proved the heterogeneity of social avoidance behaviors and the influencing effect of temperament type on the development of social avoidance behaviors in Chinese patients with breast cancer. Health professionals should pay more attention to patients who are at higher risk of developing a persistent social avoidance pattern and provide target interventions.
Is altitude a determinant of the health benefits of nature exposure? A systematic review and meta-analysis
Authors: Kim Eunsoo , Park Sujin , Kim Soojin , Choi Yeji , Cho Jae Hyoung , Kim Geonwoo 
Published: November 2022

IntroductionNature exposure is a widely accepted option for promoting public health owing to the recent surge of scientific evidence. However, the actual settings to facilitate this initiative is yet to be extensively reviewed. In this systematic review, we have aimed to provide an up-to-date summary of interventional studies investigating the psycho-physiological effects of forests and urban forests, including details on their physical settings, and investigate an effect-modifying role of altitude and summarize data on the magnitude and shape of the association.MethodsA keyword search using five electronic academic databases (PubMed, Embase, PsycINFO, Web of Science, and Scopus) was conducted to identify relevant articles published in English from the inception year to the end of February 2022. The methodological quality was evaluated using the ROBINS-I or ROB2 tool, depending on the study design. Meta-regression and random effects model were jointly used to examine the relationship between altitude and health outcomes.ResultsWe included 27 eligible studies and 31 cases extracted from 19 studies were used for the meta-analysis. In the meta-regression, we observed a non-linear association between altitude and psycho-physiological effects. Altitude had a positive quadratic association with anxiety (p &lt; 0.000, adjusted R2 = 96.79%), depression (p &lt; 0.000, adjusted R2 = 98.78%), and fatigue (p &lt; 0.000, adjusted R2 = 64.74%) alleviating effects. Conversely, altitude demonstrated a negative non-linear association with the blood pressure-lowering effect (p = 0.009, adjusted R2 = 32.83%). Additionally, the thermal index (THI) and illuminance (lx) levels were significantly associated with effect sizes of psychological restoration.DiscussionThis review provides moderate-certainty evidence for an effect-modifying role of altitude. The meta-regression results suggested the optimal and minimal altitude ranges for psychological restoration and physiological relaxation, respectively. Despite some limitations, the study findings provide a significant basis for utilizing altitude, which is easily accessible and simple, to promote the health benefits of nature-based initiatives.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022310894, identifier: CRD42022310894.
Innovation and financial sustainability in China's long-term care insurance: An empirical analysis of the Nantong pilot
Authors: Guo Peng , Li Yajun 
Published: November 2022

BackgroundAgainst a backdrop of aging and declining birthrates, the demand for long-term care insurance (LTCI) systems in various countries throughout the world continues to rise. Most traditional LTCI systems only cover a limited group of people, which cannot solve the problem of nursing needs among other groups, and, further, it makes financial sustainability very difficult to achieve.PurposeThis article aims to explore how Nantong successfully achieves both “full coverage” and “financial sustainability” through institutional innovation.ObjectsInstitutional innovation logic and financial sustainability of LTCI system in Nantong, one prefecture-level city with the highest degree of aging in China.MethodsThrough field interviews and research, this article examines the LTCI system in Nantong, exploring its logic and its successful realization of institutional innovation, which combines international and local experience. The study further uses quantitative methods to measure the system's financial sustainability.DataFrom the seventh national population census bulletin, the 13th Five-Year population development plan, the Nantong Municipal Bureau of Statistics and Nantong Statistical Yearbook 2020 from Nantong government. And from the authors' field survey data in the Medical Insurance Bureau of Nantong.ResultsThe findings reveal that the Nantong model effectively disperses institutional risks by means of horizontal and vertical transfer payments, diversified financing, and service outsourcing, achieving its dual goals of full coverage and financial sustainability in the long run.ConclusionNantong Model has interrupted the path dependence of traditional dual systems and the philosophy of fragmented institutional construction. Nantong's path-breaking institutional construction paradigm has important theoretical and practical value.ContributionsThe experience of Nantong may prove valuable and instructive, for not only other cities in China but also developing countries across the globe.
The perceived built environment and general physical activity: An exploratory study in Jordan
Authors: Saadeh Rami , Obaidat Ahmed , Allouh Mohammed Z. 
Published: November 2022

Introduction:The built environment affects the health and wellbeing of the population. The main purpose of this study was to explore the association between the perceived built environment and general physical activity among Jordanians.MethodsThis cross-sectional study was conducted in Jordan between August and November of 2019 using an online self-administered questionnaire distributed to Facebook groups that are commonly used among the Jordanian population. Descriptive statistics using chi-square test of independence was used to examine the relationship between demographic information and the perceived built environment with physical activity.Results and discussionA total of 1,124 participants were involved in the study with the majority being middle-aged (91.5%), females (67.7%), undergraduates (68.1%), and living in urban areas (71.2%). Most study participants (68.2%) were neither physically active ‘at least two times per week' nor using parks for routine physical activity (82.5%). Regarding the association of demographic information with physical activity, gender was significantly associated with weekly physical activity, whereas age and monthly income were significantly associated with routine walking or biking. Further, on the one hand, gender, residency, and monthly income were significantly associated with physical activity at the park (p ≤ 0.05). On the other hand, the availability of specific biking paths, having good and accessible places for physical activity, was among the built environment factors that were significantly associated with weekly physical activity (p ≤ 0.05). Some characteristics of the perceived built environment were associated with physical activity. Therefore, enhancing the built environment is considered a cornerstone in any national health behavior plan that includes physical activity as one of its components.
Enhanced Photoluminescence of Gd3Al4GaO12: Cr3+ by Energy Transfers from Co-Doped Dy3+
Authors: Zhang Yu , Li Xiang , Hu Dahai , Sa Qier , Wang Xinran , Wang Fengxiang , Wang Kaixuan , Zhou Xuelian , Song Zhiqiang , Liu Yongfu , Chao Kefu 
Published: November 2022

LEDs for plant lighting have attracted wide attention and phosphors with good stability and deep-red emission are urgently needed. Novel Cr3+ and Dy3+ co-doped Gd3Al4GaO12 garnet (GAGG) phosphors were successfully prepared through a conventional solid-state reaction. Using blue LEDs, a broadband deep-red emission at 650–850 nm was obtained due to the Cr3+ 4T2 → 4A2 transition. When the Cr3+ concentration was fixed to 0.1 mol, the crystal structure did not change with an increase in the Dy3+ doping concentration. The luminous intensity of the optimized GAGG:0.1Cr3+, 0.01Dy3+ was 1.4 times that of the single-doped GAGG:0.1Cr3+. Due to the energy transfer from Dy3+ to Cr3+, the internal quantum efficiency reached 86.7%. The energy transfer from Dy3+ to Cr3+ can be demonstrated through luminescence spectra and fluorescence decay. The excellent properties of the synthesized phosphor indicate promising applications in the agricultural industry.
Epidemiologia, biologia, resistência a antifúngicos e virulência do fungo emergente <em>Candida auris</em>
Authors: Pereira Creidvani Martins , De Barros Neuza Biguinati , Martins Tamara Silva 
Published: November 2022

Introdução: A Candida auris é uma nova espécie de patógeno fúngico altamente resistente e emergente que causa infecções invasivas graves. O objetivo desse estudo é realizar um levantamento sobre o gênero Candida, destacando características gerais, fatores de risco, epidemiologia e tratamento, bem como os mecanismos de resistência aos medicamentos antifúngicos. A epidemiologia das infecções invasivas por C. auris sofreu mudanças dramáticas, assim estabeleceu como um importante causa de morbidade e mortalidade afetando adultos e crianças com uma variedade de fatores de riscos que representa uma nova ameaça nosocomial que exigirá um controle de infecção aprimorado em diversos ambientes de saúde e comunitários. Para combater infecções por C. auris novos métodos de terapia, drogas e ferramentas estão sendo testados como uma demanda urgente. A prevalência de C. auris atinge anualmente números preocupantes, a incidência é prejudicada por estar relacionada as contrariedades na identificação correta. Por isso, estima-se que o número de casos de C. auris seja muito maior do que os dados relatados. Essa informação se justifica devido a gravidade do fungo ser multirresistente e com a complexidade de transmissão e do alto número de pacientes imunocomprometidos suscetíveis ao contágio e desenvolvimento das formas mais graves da doença.
PENERAPAN PEWARNAAN GRAF PADA PENJADWALAN WORK FROM HOME (STUDI KASUS KANTOR PENGAWASAN DAN PELAYANAN BEA DAN CUKAI TIPE MADYA PABEAN C BLITAR)
Authors: Hida Amaliya Asyraful , Robby Rizka Rizqi 
Published: November 2022

Virus Corona telah mewabah di Indonesia sejak awal Maret dan menyebar luas hampir ke seluruh provinsi di Indonesia yang mengakibatkan perubahan dalam berbagai aspek kehidupan manusia. Berbagai kebijakan telah dikeluarkan untuk meminimalisir penyebaran COVID-19 salah satunya adalah diberlakukannya PSBB (Pembatasan Sosial Berskala Besar), dengan diberlakukannya PSBB, hal ini mengakibatkan terganggunya aktifitas masyarakat karena adanya pembatasan dalam berbagai hal salah satunya kegiatan bekerja. Kantor Bea Cukai Blitar menerapkan Work From Home (WFH) dengan aturan minimal 50 persen orang yang melaksanakan Work From Home (WFH). Penyusunan jadwal WFH (Work From Home) merupakan sebuah contoh penjadwalan yang harus dilakukan oleh KPPBC TMP C Blitar, untuk memecahkan masalah penjadwalan tersebut akan dilakukan analisis menggunakan teori graff yaitu pewarnaan, dan diolah dengan Algoritma Welch-Powell. Algoritma Welch-Powell dapat digunakan untuk mewarnai sebuah graf G secara efisien. Dari penelitian yang dilakukan dengan menggunakan algoritma Welch-Powell untuk mewarnai penjadwalan WFH menghasilkan penyusunan jadwal yang lebih efektif. Didapatkan hasil bahwa pewarnaan titik pada Subbagian Umum dihasilkan empat warna dengan bilangan kromatik 4, pewarnaan titik pada Seksi Penindakan dan Penyidikan menghasilkan empat warna dengan bilangan kromatik 4, pewarnaan titik pada Seksi Perbendaharaan menghasilkan 5 warna dengan bilangan kromatik 5, pewarnaan titik pada Seksi KIP menghasilkan 4 warna dengan bilangan kromatik 4, serta pewarnaan titik pada Seksi PKCDT menghasilkan empat warna dengan bilangan kromatik 4.
O RECONHECIMENTO DO POVO QUILOMBOLA DE CACHOEIRA PORTEIRA
Authors: Leão Marcus Vinicius 
Published: November 2022

O povo quilombola vem sofrendo graves ataques e perseguiçõesdas mais diversas formas, promovidospelo Governo Brasileiro que prioriza interesses particulares, vindo a massacrar os povos e populaçõestradicionais, entre eles os afro-descedentes.A Comunidade Quilombola de Cachoeira Porteira no Estado do Pará é uma destascomunidades que sofre com a falta de interesse do governo, pois a comunidade seencontra em um impasse legislativo grave que merece atenção do poder públicopara a regularização das terras quilombolas.
ENSINO FUNDAMENTAL I - CURRÍCULOS PENSADOSPRATICADOS: UM DESAFIO NO COTIDIANO NO PROCESSO DE ENSINO-APRENDIZAGEM DO ALUNO
Authors: Louvem Josiane Cássia 
Published: November 2022

RESUMO O objetivo deste artigo buscou contribuir para ampliação e problematização do debate das relações de rigor das prescrições curriculares e o modo como se processa na prática docente no ensino-aprendizagem em sala de aula. Tem como principal argumento favorável à perspectiva do cotidiano como ponto de partida e de chegada da construção do conhecimento. Além de ser também o meio de superar as falas e escritas retóricas do mundo acadêmico, herdeiras da ciência moderna, que se propõem neutras e racionais, desconsiderando os sujeitos que vivem e praticam no cotidiano escolar, com uma política de desvalorização das práticas cotidianas dos professores que passa por imposição de manuais que buscam direcionar o seu trabalho. Por fim, ressalta que o cotidiano escolar demonstra as forças de movimentos existentes nas escolas de ensino fundamental para superar as dicotomias herdadas pela educação do discurso hegemônico da ciência moderna. Pode se concluir, a partir da revisão teórica, que o currículo não pode ser visto como um espaço neutro, sendo preciso repensar a as práticas desenvolvidas em sala de aula haja vista que cada ano e série a escola recebe novos sujeitos que chegam com novas demandas e expectativas, é preciso nos inventar a cada dia discutindo a complexidade inserida no cotidiano da educação.Palavras-chave: Currículo. Didática. Práticas Emancipatórias. Cotidiano Escolar.
A CULTURA E RELIGIOSIDADE DO CONGO CAPIXABA
Authors: Costa Douglas Pinheiro 
Published: November 2022

Este ensaio tem por objetivo compreender a cultura do Congo Capixaba e as relações existentes entre a religiosidade presente na manifestação popular do estado do Espírito Santo. Esta pesquisa bibliográfica levanta informações a respeito da história desta manifestação, suas raízes culturais indígenas e afro-brasileiras, características peculiares como os instrumentos e vestimentas, as funções e papéis dos participantes, personagens folclóricos e as principais festividades da região metropolitana que transitam entre o sagrado e o profano. PALAVRAS-CHAVES: Cultura, Congo capixaba, Religiosidade.
O RETRATO DA INTOLERÂNCIA RELIGIOSA NO BRASIL E OS MEIOS DE COMBATÊ-LA
Authors: Dos Santos Marvila Simões Anélia dos Santos Marvila , Pereira Salaroli Tatiane Pereira 
Published: November 2022

A intolerância religiosa é algo pertinente e têm ganhado grandes proporções na sociedade brasileira. Por isso este trabalho pretende apresentar de forma sucinta a importância do Ensino Religioso para a educação pública, como um dos mecanismos no combate a intolerância religiosa no Brasil. Como componente curricular, significa que tal disciplina objetiva trabalhar a história das religiões e seus conceitos de modo a conhecer, compreender e respeitar a diversidade religiosa. O trabalho divide-se em três partes; primeiramente serão apresentados alguns fatores que contribuem para a discriminação religiosa, levando em conta a falta de conhecimento do indivíduo, em seguida um breve relato do que promulga a lei diante do problema, e por fim a contribuição da educação atrelada à disciplina Ensino Religioso frente à diversidade e intolerância religiosa. Palavras-chave: Intolerância Religiosa, Lei Constitucional, Educação, Ensino Religioso.
LEITURA COMUNITÁRIA DA BÍBLIA: UMA PROPOSTA DE LEITURA BÍBLICA PARA AS COMUNIDADES CRISTÃS NA CONTEMPORANEIDADE
Authors: Satjyambula Satya Piedade 
Published: November 2022

O presente artigo pretende discutir a leitura comunitária da Bíblia como proposta de inserção do cristianismo no mundo contemporâneo. Parte do pressuposto de que o cristianismo é comunitário logo emsua gênese. Talvez, devido ao fato deo mesmo ter surgido num ambiente onde a vivência comunitária era muito forte, no contexto da Palestina. A sociedade atual, também chamada de Pós-moderna, tem caraterísticas muito distintas daquelas verificadasno berço do cristianismo. Nesse sentido, o que o caracteriza é seu viver comunitário, embora esteja inserido numa sociedade que exacerba os direitos individuais em detrimento dos coletivos, sendo o relativismo e o desengajamento tambémmarcas fortes dessa sociedade. Como o cristianismo é uma religião que lida com a interpretação de textos e está inserida nesta sociedade individualista, pode adotar uma postura hermenêutica também individualista, buscando nas Escrituras “elementos” que justifiquem a satisfação dos desejos individuais dos fiéis, esquecendo-se desta forma, de preservar a vivência emcomunidade, que é sua premissa. Portanto, à luz desses pressupostos, a proposta da leitura comunitária aqui é apresentada como um dos elementos que contribuem para uma forma saudável de vida cristã, que é, antes de tudo, comunitária. Nesse sentido, o artigo investigará as características do mundo contemporâneo, o conceito de comunidade, bem como as principais características da Leitura Popular da Bíblia. Palavras-chave: Pós-modernidade, Contemporaneidade, Comunidade, Leitura Comunitária da Bíblia.