bluuebunny/crossref_metadata_2025_split huggingface dataset:
Insulin Edema in an Adolescent Girl with Newly Diagnosed Type 1 Diabetes Mellitus
Authors: Krishnan Rekha , Bindu S. , Riaz I. , Preethi M. S. 
Published: February 2022

Background:
Insulin edema is a rare complication that can occur following either initiation or intensification of insulin treatment in Type 1 diabetes mellitus (DM). It is an under reported condition. Awareness of this complication among physicians is important for early identification of this condition, and prompt initiation of treatment.

Clinical Description:
We present an 11-year-old girl with 2-month history of weight loss and 1-month history of polyuria and polydipsia who presented to us in moderate diabetic ketoacidosis. She developed anasarca and pulmonary edema 3 days after starting insulin. She also developed transaminitis a serum serum glutamic-oxaloacetic transaminase of 81 U/L and serum glutamic pyruvic transaminase of 83 U/L. A diagnosis of insulin edema was established after ruling out other causes like severe anemia, renal, cardiac and allergic causes. We also present a brief review of seven similar cases that we identified on a literature search.

Management and Outcome:
This included salt and fluid restriction along with diuretics. Edema resoled after 4 days of treatment, while transaminitis took 7 days to normalize.

Conclusion:
This case report highlights the importance of early recognition of the rare complication of insulin edema which can avoid unnecessary anxiety on the part of both treating physicians and parents of patients with Type 1 DM.
Lymphocytic Interstitial Pneumonia in an Infant with Diffuse Cystic Pulmonary Tuberculosis
Authors: Tsanglao Wonashi R. , Miachieo Nounechutuo , Ao Moakumla K. , Aier Tenukala , Kikon Sulanthung 
Published: February 2022

Background:
Lymphocytic interstitial pneumonia (LIP) is a rare disorder causing diffuse involvement of the lung parenchyma, including cystic changes. It is generally associated with autoimmune diseases in adults and human immunodeficiency virus infection in children. Concurrent LIP with pulmonary tuberculosis (TB) is rare and has not been reported in the pediatric population.

Clinical Description:
An 8-month-old infant who was recently diagnosed with miliary pulmonary TB and on antitubercular treatment presented with fast breathing for 2 days. Salient examination findings were tachypnea, with oxygen saturation of 84% in room air. High-resolution computed tomography of the chest showed diffuse involvement of both lungs with bilateral cystic changes. Histopathological examination of a lung biopsy specimen was consistent with LIP.

Management:
First-line antitubercular therapy was continued as per the national guideline, and methylprednisolone pulse was administered for 3 days followed by maintenance prednisolone for 8 weeks. The child responded well clinically and was kept under close follow-up. Radiological improvement became apparent at 15-month follow-up.

Conclusion:
Presence of diffuse cystic lung disease in pulmonary TB should raise suspicion for LIP. Lung biopsy is diagnostic and should be considered in such cases.
Apparent Mineralocorticoid Excess - A Rare Cause of Endocrine Hypertension
Authors: Verma Sonali , Dabadghao Preeti , Moirangthem Amita 
Published: February 2022

Background:
Endocrine causes of hypertension constitute a very small percentage of patients with secondary hypertension. Apparent mineralocorticoid excess (AME) is a rare genetic form of young-onset secondary hypertension.

Clinical Description:
We present a case of a 16-year-old boy who was diagnosed with hypertension at 5 years of age, had recurrent episodes of hypokalemic paralysis, and deranged renal function for 1 year. Hypertension was uncontrollable with multiple antihypertensive agents until an aldosterone antagonist (spironolactone) was added. Clinical history and evaluation could not identify any secondary causes of hypertension. There was no significant family history. Growth and puberty were age-appropriate.

Management and Outcome:
Endocrine workup was planned considering hypokalemia and metabolic alkalosis. This demonstrated hyporeninemic hypoaldosteronism and raised the possibility of AME and Liddle syndrome. Clinical exome sequencing revealed a probable diagnosis of AME due to a novel homozygous variant (c.911A>G) in HSD11B2 gene. Sanger sequencing confirmed heterozygosity of the same variant in both parents.

Conclusion:
A novel homozygous variant was found in HSD11B2 gene in a subject with early-onset hypertension associated with hypokalemic metabolic alkalosis, establishing the diagnosis of AME. The use of an algorithmic approach and individualized planning of genetic studies can help in early diagnosis. This helps clinicians to select the appropriate antihypertensive drug, attain good control, and prevent the development of end-organ damage. A high index of suspicion should be kept for AME and other hyporeninemic hypoaldosteronism conditions in the case of early-onset hypertension.
Jatropha Curcas Poisoning in a Family from Rural Haryana
Authors: Choudhary Sangeeta , Gupta Surbhi , Sharma Nidhi 
Published: February 2022

Background:
Jatropha curcas is a flowering plant found all over the world. It has traditionally been used for medicinal purposes and as an ornamental plant. Lately, it is being promoted for biodiesel production. Since it is a commonly grown plant with seeds that are often mistaken as edible nuts, accidental ingestion is common among children. The presence of various plant toxins results in gastrointestinal, hepatic renal cardiotoxic, and hemolytic manifestations. The general public and most pediatricians are unaware of this.

Clinical Description:
We report a case series of thirteen children who presented to the emergency department with lethargy, abdominal pain, vomiting, and diarrhea after acute ingestion of seeds of an unknown plant. The presentation varied in severity of symptoms as well as degree of dehydration, which seemed to correspond to the number of seeds consumed. The parents were asked to bring parts of the plant and the seeds were identified to belong to the Jatropha curcas plant after expert botanical consultation.

Management and Outcome:
All the children were admitted. None of them had manifestations of any specific toxidrome, however, there seemed to be isolated gastrointestinal involvement, clinically. Gastric lavage was done immediately. Intravenous fluid correction was administered based on the severity of dehydration. Supportive treatment with antiemetics and antacids was provided. Baseline investigations were planned to rule out organ dysfunction. The most common derangement was neutrophilic leukocytosis. All children recovered well without any complications or sequelae.

Conclusion:
Jatropha Curcas is a noxious plant that should not be grown in areas where children play. Unknown plant poisoning should be treated with the same gravity as any other poisonous substance. All efforts should be taken to look for indicators of a specific toxidrome in case an antidote is warranted, as well as identify the concerned plant.
Comparison of Knowledge, Attitude, Practices, and Psychological Impact of COVID-19 among the Urban and Rural Population of Bangalore, Karnataka
Authors: Bhat Nuthan , Salam Hiba , Javvaji Sushma , Chakraborty Ananya 
Published: February 2022

Context and Objectives:
There is a strong urban-rural divide in India in terms of education, economic status, and availability of health care. This became more prominent during the COVID-19 pandemic. Hence, the government emphasized on preventive aspects, especially in terms of safety practices. With this context, this study sought to evaluate and compare the knowledge, attitudes, practices, and psychological impact of COVID-19 among the urban and rural population of Bangalore to study the differential effects on both communities.

Materials and Methods:
An online questionnaire was distributed to 142 participants between December 1 and 31, 2020. The goal was to receive responses from both urban and rural population of Bangalore. Informed consent was taken from all participants. The response scores were tabulated and analyzed using statistical software.

Results and Conclusion:
A total of 138 responses were evaluated. In comparison to the urban population, there was a statistically significant link between inferior education and occupation in the rural population. (P 0.001). There was a statistically significant difference between rural and urban respondents in terms of knowledge (P 0.001) and attitude (P 0.05). The rural population's COVID-19 practices and the psychological impact were shown to be worse, but this was not statistically significant. A holistic approach is required to increase the rural population's knowledge and practices to integrate them with the rest of the country and combat the COVID-19 pandemic more effectively.
Effect of automobile exhaust on pulmonary function tests among traffic police personnel in Kashmir valley
Authors: Naik Muzafar , Amin Aabid , Gani Mehfooza , Bhat Tariq Ahmed , Wani Abdul Ahad 
Published: February 2022

Background:
Automobile exhaust is an important cause of air pollution, which is a leading health menace and is growing perpetually. Traffic police personnel are exposed to automobile exhaust more than anyone else, and the resulting lung involvement may be asymptomatic.

Materials and Methods:
This observational cross-sectional study was conducted among 136 traffic police personnel, aged 18–59 years, working for more than 6 months in the traffic police of Kashmir valley. In addition, 140 age- and sex-matched, healthy unexposed Kashmiri’s served as controls. Pulmonary functions were measured by RMS Helios 401 PC based spirometer.

Results:
Sixteen (11.2%) out of 136 traffic police personnel had abnormal pulmonary function test (PFT) as compared to 5 (3.6%) out of 140 controls. Traffic police personnel’s had significantly declined forced expiratory volume in 1 s (FEV 1) and forced vital capacity. Eight (5.8%) had obstructive, 7 (5.1%) had restrictive, and 1 (0.7%) traffic police personnel had mixed pattern on PFT. Duration of exposure to automobile exhaust of more than 10 years was significantly associated with pulmonary function abnormality (P = 0.038).

Conclusion:
Air pollution due to automobile exhaust may be the factor responsible for pulmonary function abnormalities in traffic police personnel. Besides protective measures during duty hours, traffic police personnel should be subjected to periodic assessment of their lung functions.
Good survival rate, moderate overall and good respirator quality of life, near normal pulmonary functions, and good return to work despite catastrophic economic costs 6 months following recovery from Acute Respiratory Distress Syndrome
Authors: Thomas Rohan , Turaka Vijay Prakash , Peter John Victor , Christopher DJ , Balamugesh T , Mahasampath Gowri , Mathuram Alice Joan , Sadiq Mohammed , Ramya I , George Tarun , Chandireseharan Vignesh , George Tina , Sudarsanam Thambu David 
Published: February 2022

Introduction:
Long-term quality of life, return to work, economic consequences following Acute Respiratory Distress Syndrome (ARDS) are not well described in India. This study was aimed to address the question.

Methods:
A prospective cohort study of 109 ARDS survivors were followed up for a minimum of 6 months following discharge. Quality of life was assessed using the SF-36 questionnaire. Respiratory quality was assessed using the St Georges Respiratory Questionnaire. Time to return to work was documented. Costs-direct medical, as well as indirect were documented up to 6 months.

Results:
At 6 months, 6/109 (5.5%) had expired. Low energy/vitality and general heath were noted in the SF-36 scores at 6 months; overall a moderate quality of life. Pulmonary function tests had mostly normalized. Six-min walk distance was 77% of predicted. Respiratory quality of life was good. It took at the median of 111 days to go back Interquartile range (55–193.5) to work with 88% of previously employed going back to work. There were no significant differences in the severity of ARDS and any of these outcomes at 6 months. The average total cost from the societal perspective was

JOURNAL/luin/04.03/01408641-202203000-00012/169FF01/v/2022-09-30T154518Z/r/image-tiff

231,450 (standard deviation 146,430 -, 387,300). There was a significant difference between the 3-ARDS severity groups and costs (P < 0.01). There were no independent predictors of return to work.

Conclusion:
ARDS survivors have low 6-month mortality. Pulmonary physiology and exercise capacity was mostly normal. Overall, quality of life is average was moderate, while respiratory quality of life was good. Return to work was excellent, while cost of care falls under a catastrophic heath expense.
Association of menstrual pattern with lifestyle factors among female medical students
Authors: Namdev Garima , Naz Sabiha 
Published: February 2022

Introduction:
Menstrual disorders are more frequently observed among young females, especially medical students nowadays. Various lifestyle factors such as frequent consumption of fast foods, dietary habits, physical exercise, and yoga practicing play a very great role in alteration of menstruation pattern. All of these variables are affected by weight gain which is determined by body mass index (BMI), which itself affect menstrual pattern.

Aims and Objectives:
The aim of this study was to determine the association of menstrual pattern with lifestyle factors and BMI among medical students.

Materials and Methods:
A cross-sectional observational study was done among sixty undergraduate female medical students with the help of pretested and predesigned questionnaire consisting of menstrual pattern, premenstrual syndrome (PMS), and dysmenorrhea along with details about lifestyle factors. Anthropometric measurements such as weight, height, and BMI were also taken. Chi-square test was applied to test the association between menstrual pattern and lifestyle factors.

Results:
Out of total, 60% of students had regular cycle, 63% had dysmenorrhea, and 75% possess PMS. Majority of obese (65.2%) students had irregular cycle and 52.1% suffered from dysmenorrhea. Maximum 91% and 77.4% of students had regular cycle practicing yoga and physical exercise, respectively, whereas 86.2% of students suffered from PMS among those not exercising regularly. All of these findings were found statistically significant.

Conclusion:
More than half of students possess regular cycle. Overweight and obesity were found to be associated with irregular menstrual cycle and dysmenorrhea. Lifestyle factors such as yoga practicing, frequent consumption of fast foods, and regular physical exercise affect menstrual pattern in the present study.
A study of knowledge, attitude, and practice of Pap smear test in the early detection of cervical cancer among qualified working women in an urban area
Authors: Vincy Reethu , Umashankar T. 
Published: February 2022

Introduction:
Cervical cancer (CC) is being one among the leading causes for cancer-related deaths worldwide contribute to a massive portion of mortality which can be reduced to a great extent with the help of a screening test – Pap smear test; with which early detection and thus prevention of this cancer is made possible. Despite the fact that Pap smear test has proved itself to be an easily available and cost-effective method to screen the early signs of CC among prone women, a large group of women is hesitant to get it done due to various reasons. Hence, this was conducted to study the degree of knowledge, attitude, and practice of Pap smear test among qualified working women in urban areas.

Materials and Methods:
In this cross-sectional study, 334 working-class women who had an undergraduate/postgraduate qualification and were engaged in different types of occupation were selected. These participants were requested to answer a questionnaire which extracted information about the individual's demographic data; knowledge, attitude, and practice regarding CC, Pap smear test, and Human papillomavirus vaccination. Data so collected were analyzed using the SPSS version 23 software.

Results:
The participants belonged to the age group of 22–59 years with mean age being 33.4 years. The study population was broadly categorized into two groups as teaching occupation (n = 221; 66.2%) and nonteaching occupation (n = 113; 33.8%). Overall, 45% of the participants knew that CC is the cancer of the lower part of uterus. Forty-five percentage did not know the benefits of Pap smear test. Knowledge sourced from family, friends, and health care professionals was 30% and 6%, respectively. Medical camps contributed to 17% of the knowledge in the overall study group. Forty-nine percentage of the participants did not know Pap smear test has to be done regularly. Overall, only 26 participants (8%) underwent Pap smear test. Most of them were in the age range of 31–40 years and the least were in the age range of 21–30 years. Knowledge and attitude toward Pap smear test are the major indicators and predictors of the utilization and performance of this test. The practice of doing Pap smear test and thus the performance of this test was higher among those who had higher knowledge (Group II P < 0.005) and better attitude toward Pap smear test. Studies reveal that pain, lack of knowledge, insufficient medical recommendations, and health education, time constraints, embarrassment, and fear of bad results are the main barriers in getting Pap smear test done. This brings to light the need to revamp our strategy in health education.
Mucocutaneous side effects of gefitinib
Authors: Thekkath Ruhaila , Nonam Chellappan , Mathew Rani , Sunny Beena 
Published: February 2022

Background:
Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein which is expressed in various tissues. Aberrant EGFR signaling plays an important role in carcinogenesis. Gefitinib, an EGFR inhibitor, is a promising drug in treatment of various malignancies. Awareness about the various mucocutaneous side effects of gefitinib will help in optimum management. Hence, we decided to conduct this study.

Materials and Methods:
We did a descriptive study and observed the various cutaneous side effects in 40 patients who were treated with gefitinib in a tertiary care center in South Kerala.

Results:
Dermatological adverse reactions were observed in 87.5% of our patients, the most common being dryness and pruritus in 67.5% and 65% of patients, respectively. Rashes were of Grade 1/2 severity in most of our cases.

Conclusions:
Cutaneous reactions, though common, were mild in majority of our patients. Studies with more sample size and follow-up are needed to improve our knowledge.
La inteligencia emocional en la educación, tips para desarrollar en el aula
Authors: González Mayté Cadena , Bojórquez María Alejandra Sarmiento , Rosado Juan Fernando Casanova 
Published: February 2022

Hoy en día las TIC han ido innovando la forma en que el alumno aprende, ya que se considera que el alumno debe: aprender a conocer, aprender a hacer, aprender a vivir juntos y aprender a ser. Generalmente los docentes cubrimos perfectamente bien las dos primeras premisas y quizás la tercera, pero no atendemos la última ¿estamos contribuyendo a su formación integral?;¿realmente estamos propiciando el desarrollo de competencias? Necesitamos aplicar estrategias o ciertos tips para propiciar en él la aptitud tanto personal como social, para que alcance éxito en la vida. Necesitamos que se conozcan ellos mismos para canalizar sus emociones a favor de su aprendizaje. En este trabajo basado en la experiencia se proponen tips que el docente debe utilizar para hacer consiente al alumno de sus emociones y pueda desarrollar su Inteligencia Emocional y esta a su vez impacte en su proceso de aprendizaje ayudando al desarrollo de competencias. La inteligencia emocional implica, entre otras habilidades, ser capaz de motivarse y persistir frente a las decepciones; para desarrollar la inteligencia emocional el alumno debe: expresar sus emociones, decir lo que piense, aplicar el esquema de valores, reconocer aciertos y desaciertos, leer libros de superación personal, adoptar una actitud de… yo puedo, trabajar en equipo para fomentar cooperación. Queremos que el alumno no solamente tenga éxito académicamente, sino también éxito en su vida.
Pengaruh Kompensasi, Disiplin Kerja, Dan Motivasi Kerja Terhadap Kinerja Karyawan Pada PT. Shinko Plantech Banten
Authors: Sari Bunga Permata , Pancasasti Ranthy Pancasasti 
Published: February 2022

Tujuan dari penelitian ini untuk mengetahui pengaruh kompensasi (X1), disiplin kerja (X2), dan motivasi kerja (X3) terhadap kinerja karyawan (Y). Pengolahan data menggunakan aplikasi SmartPLS (Partial Least Square) dengan teknik pengujian model pengukuran (Inner Model), teknik pengujian model struktural (Outer Model) serta pengujian hipotesis. Terdapat populasi 127 karyawan PT.Shinko Plantech dan bersama metode simple random sampling, terdapat sampel yang digunakan 85 responden. Penelitian dilakukan dengan metode deskriptif kuantitatif, dan asosiatif hubungan kausal. Kebaharuan (novelty) dalam penelitian ini adalah (1) objek dalam penelitian yaitu karyawan tetap pada PT.Shinko Plantech dengan variabel penelitian yaitu kompensasi, disiplin kerja, motivasi kerja dan kinerja karyawan yang belum pernah diteliti sebelumnya, (2) kompensasi tidak berpengaruh langsung terhadap kinerja karyawan, akan tetapi disiplin kerja dan motivasi kerja berpengaruh langsung terhadap kinerja karyawan pada PT.Shinko Plantech. Hasil penelitian menunjukan bahwa kompensasi tidak berpengaruh langsung signifikan terhadap kinerja karyawan. Disiplin kerja dan motivasi kerja berpengaruh langsung positif signifikan terhadap kinerja karyawan masing-masing sebesar 26,50% dan 29,53%.
Kata kunci: Kompensasi, Disiplin Kerja, Motivasi Kerja dan Kinerja Karyawan
A gestão de ilegalismos de Foucault como categoria de análise de questões jurídicas no Brasil
Authors: Maia Gretha Leite , Oliveira David Barbosa 
Published: February 2022

A proposta desse artigo é examinar e fornecer um subsídio teórico e analítico para pesquisas jurídicas. Para tanto, empreendeu-se uma pesquisa exploratória que investigou a ferramenta “ilegalismo” e suas possíveis contribuições como categoria de análise para definir e explicar problemas normativos e a atuação do judiciário na modernidade. O principal referencial é Foucault, cuja leitura foi feita de par com as contribuições de Delleuze sobre Foucault. Foram feitos também aportes significativos das leituras de Rusche e Kirchheimer sobre o debate. Examinada essa possibilidade, restará estabelecida uma categoria de análise válida para estudos da atuação do judiciário brasileiro. Trata-se, por fim, de pesquisa bibliográfica, exploratória, de caráter teórico e analítico.
Letters Concerning Taste (And) Essays
Authors: Cooper John Gilbert , Moor James 
Published: February 2022

John Gilbert Cooper was a British poet and writer, and one of the chief contributors to Robert Dodsley’s Museum (1946-7). His Letters Concerning Taste (And) Essays (1754) is considered the first volume on the subject of taste. Written in an epistolary style, the work sets out letters to classical figures such as Euphemius, Philemon, Leonora and Eugenio.
Writings about art and creativity can be traced to the texts of classical antiquity, but aesthetics as a separate and systematic area of philosophy is almost wholly a product of the 18th century. It was at that time that philosophers began to treat notions about creativity and our responses to it with a kind of philosophical rigour found in epistemology and metaphysics. 18th-century authors, such as John Gilbert Cooper, sought to define what poetry, literature, painting and sculpture were and to determine the links between the various forms of artistic expression. Like Cooper, many questioned whether artistic sensitivity could be acquired or was innate, asking how good taste was cultivated and maintained.