bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors affecting contraceptive use among currently married women in Iraq in 2018
Authors: Abdelaziz Wafaa , Nofal Zohdy , Al-neyazy Suhair 
Published: March 2022

AbstractLevel of contraceptive use is one of the primary proximate determinants of fertility level. Among Arab countries, Iraq experiences high fertility rates, especially among adolescents. According to the 2018 Iraq Multiple Indicator Cluster Survey (IMICS 2018), 52.8% of currently married Iraqi women used a contraceptive method (36.1% used modern methods, and 16.7% used traditional methods). A multiple multinomial logistic regression model was adopted to investigate the demographic, socioeconomic, fertility, and cultural determinants of contraceptive use among currently married, nonpregnant Iraqi women based on the 2018 Iraq Multiple Indicator Cluster Survey data. The main findings indicated that women using modern contraceptive methods had more children, did not experience the death of a child, and had no desire for more children. Moreover, they were married before age 21, had at least an upper secondary education, had access to mass media, used the internet, belonged to a low or middle wealth category, and lived in urban Kurdistan. Kurdish women prefer to use traditional methods. The results suggest that family planning programmes should target women who live in southern/central areas of Iraq, as they were the least likely to use contraceptives, and motivate Kurdish women to use modern contraceptives rather than traditional contraceptives.
Blood calcium dynamics in cows receiving an aqueous calcium suspension for voluntary consumption or a calcium bolus following parturition
Authors: Wilms Juliette N. , Daniel Jean-Baptiste , Martín-Tereso Javier , Klop Arie , Goselink Roselinde , Han Yanming , van Kuijk Sandra 
Published: March 2022

AbstractThe form of oral calcium (Ca) supplement and the Ca source influence Ca absorption dynamics resulting in different postpartum calcemia. The objective of this study was to investigate whether an oral Ca supplement (mainly CaCO3) offered for voluntary consumption would maintain or increase postpartum blood Ca to the same degree as a Ca bolus (mainly CaCl2) providing an equivalent dose of a Ca. A total of 72 Holstein cows were blocked by expected parturition date and parity. Within each block of 3 animals, cows were randomly assigned to one of three treatments, including an oral Ca supplement offered for voluntary consumption (Ca-drink, n = 23), an oral Ca bolus (Ca-bolus, n = 24), or an untreated group (CON, n = 25). Treatments were administered once within 15 min postpartum. The Ca-drink provided 45 g of Ca (CaCO3 source) and was mixed in 20 L of lukewarm water and offered to cows for 30 min. The Ca-bolus provided 43 g of Ca (71% from CaCl2 and 29% from CaSO4) and was administered once. Both Ca-bolus and CON cows received 20-l of lukewarm water at parturition to standardize the volume of fluids (Ca-drink or 20-l lukewarm water) offered at parturition. Dairy cows offered Ca-drink had a 28% higher fluid consumption than Ca-bolus and CON cows. Milk yield and milk composition expressed in percentage protein, fat, lactose, and urea did not differ, whilst there was a small but significant increase in DMI in cows receiving the Ca-drink compared to CON, while Ca-bolus did not differ from other groups. This was consistent with reduced BW losses between week 1 and 3 in cows receiving the Ca-drink suspension. Treatment by time interactions were present for blood Ca, glucose, and urea concentrations. Blood Ca was relatively stable in Ca-drink cows, while higher fluctuations were observed in Ca-bolus cows. In Ca-bolus cows, blood Ca increased from 15 min to 6 h, decreased from 6 to 24 h, and finally increased again from 24 to 48 h. At 24 h post administration, blood Ca was greater in cows receiving the Ca-drink than cows receiving the Ca-bolus. Blood glucose was greater in Ca-bolus cows at 15 min after treatment administration compared with Ca-bolus and CON, while blood urea was higher in CON than Ca-drink and Ca-bolus throughout the sampling period. These results indicate that voluntary oral Ca resulted in a relatively stable calcemia, whereas higher fluctuations were observed in cows receiving the Ca-bolus. Due to a lack of differences between Ca-drink and Ca-bolus compared with CON, it is not possible to conclude regarding the efficacy in maintaining postpartum blood Ca.
Consolidating Product Lines via Mergers and Acquisitions: Evidence From the USPTO Trademark Data
Authors: Hsu Po-Hsuan , Li Kai , Liu Xing , Wu Hong 
Published: March 2022

AbstractUsing a new trademark-based product market competition measure and a novel trademark-merger data set over the period 1983–2016, we show that companies facing greater product market competition are more likely to be acquirers. We further show that postmerger, compared to their nonacquiring peers, acquirers consolidate their product offerings by discontinuing more existing product lines and developing fewer new product lines. Using a quasi-experiment based on bids withdrawn due to exogenous reasons helps us establish the causal effect of deal completion on product-market consolidation. We conclude that acquisitions create product market synergies by cutting overlapping product offerings to achieve cost efficiency.
A 5-year analysis of Candida bloodstream infections in the paediatric cardiovascular surgery ICU of a tertiary care centre
Authors: Karaağaç Aysu Türkmen , Şavluk Ömer Faruk , Yıldırım Ayşe İnci 
Published: March 2022

AbstractBackground:Candida infections have become one of the most common causes of morbidity and mortality in paediatric ICUs, especially following complex surgeries, all over the world. Therefore, we conducted a 5-year analysis of Candida bloodstream infections in our tertiary paediatric cardiovascular surgery ICU.Methods:One thousand nine hundred and thirty four children, 0–16-year-old, who underwent paediatric cardiovascular surgery between January 2016–June 2021 were enrolled in this retrospective study. Blood cultures obtained from 1056 patients, who needed mechanical ventilation and indwelling devices longer than 5 days and had the signs of infection according to Center for Disease Control criteria, were evaluated. The isolated pathogens were recorded. 137 with Candida bloodstream infections were reanalysed for their age, weight, cardiac pathologies, duration of mechanical ventilation, hospitalisation and antibiotic use.Results:One hundred and thirty-seven out of one thousand and fifty six patients (12.9%) had Candida growth in their blood cultures. C. albicans (n: 50, 36.5%), C. parapsilosis (n: 20, 14.6%), C. tropicalis (n: 8, 5.8%), C. glabrata (n: 5, 3.7%), and other non-albicans Candida species (n: 54, 39.4%) were isolated. The patients with Candida bloodstream infections had lower age, longer duration of mechanical ventilation, longer length of hospital stay and antibiotic use (p-values<0.05). They had cardiac pathologies as atrioventricular septal defect (18.9%), transposition of great arteries (17.6%), tetralogy of Fallot (12.4%), transposition of great arteries + double outlet right ventricle, or total anomalous pulmonary venous return + atrioventricular septal defect (37.9%), and others. The Candida bloodstream infections mortality was 11.6% (16/137).Conclusion:The most common cause of Candida bloodstream infections in the last five years in our paediatric cardiovascular surgery ICU was non-albicans Candida species. Prolonged mechanical ventilation, hospitalisation and antibiotic use, low age, and weight were found as the main risk factors that raise the morbidity and mortality rates of Candida bloodstream infections.
Unsolved problems and unwanted decision-making in the last year of life: A qualitative analysis of comments from bereaved caregivers
Authors: Knop Jannis , Dust Gloria , Kasdorf Alina , Schippel Nicolas , Rietz Christian , Strupp Julia , Voltz Raymond 
Published: March 2022

AbstractObjectivesPatients in their last year of life, as well as their relatives, often feel that existent care structures of the healthcare system do not adequately address their individual needs and challenges. This study analyzes unmet needs in terms of unsolved problems and unwanted decision-making in the health and social care of patients in their last year of life from the perspective of bereaved caregivers.MethodsThis qualitative study is based on free-text comments from informal caregivers of deceased patients collected as part of the Last-Year-of-Life-Study-Cologne (LYOL-C) using a postal survey. With qualitative content analysis, a category system with main and subcategories was developed in a multi-step process.ResultsFree-text commentaries and demographic data were collected from 240 bereaved caregivers. Particularly outside of hospice and palliative care services, study participants addressed the following unsolved problems: poor communication with medical and nursing staff, insufficient professional support for informal caregivers, inadequate psycho-social support for patients, and poor management of pain and other symptoms. Respondents often stated that their relative had to be cared for and die outside their own home, which the relative did not want.Significance of resultsOur findings suggest the necessity for greater awareness of patients’ and their relatives’ needs in the last year of life. Addressing individual needs, integrating palliative and hospice care in acute hospitals and other healthcare structures, and identifying patients in their last year of life and their caregivers could help to achieve more targeted interventions and optimization of care.
Visions of the Arctic Future: Blending Computational Text Analysis and Structured Futuring to Create Story‐Based Scenarios
Authors: Keys P. W. , Meyer A. E. 
Published: March 2022

AbstractThe future of Arctic social systems and natural environments is highly uncertain. Climate change will lead to unprecedented phenomena in the pan‐Arctic region, such as regular shipping traffic through the Arctic Ocean, urban growth, military activity, expanding agricultural frontiers, and transformed Indigenous societies. While intergovernmental to local organizations have produced numerous synthesis‐based visions of the future, a challenge in any scenario exercise is capturing the “possibility” space of change. In this work, we employ a computational text analysis to generate unique thematic input for novel, story‐based visions of the Arctic. Specifically, we develop a corpus of more than 2,000 articles in publicly accessible, English‐language Arctic newspapers that discuss the future in the Arctic. We then perform a latent Dirichlet allocation, resulting in 10 distinct topics and sets of associated keywords. From these topics and keywords, we design ten story‐based scenarios employing the Mānoa mashup, science fiction prototyping, and other methods. Our results demonstrate that computational text analysis can feed directly into a creative futuring process, whereby the output stories can be traced clearly back to the original topics and keywords. We discuss our findings in the context of the broader field of Arctic scenarios and show that the results of this computational text analysis produce complementary stories to the existing scenario literature. We conclude that story‐based scenarios can provide vital texture toward understanding the myriad possible Arctic futures.
Seasonal and Multiyear Changes in CO2Degassing at Mammoth Mountain Explained by Solid‐Earth‐Driven Fault Valving
Authors: Hilley George E. , Lewicki Jennifer L. , Baden Curtis W. 
Published: March 2022

AbstractChanges in CO2emissions from volcanoes may evidence volcanic unrest. We use a multiyear time series of CO2flux collected at the Horseshoe Lake Tree Kill area on Mammoth Mountain, CA, to understand processes that cause variations in flux from this system. Seasonal variations are systematically lowest during the winter months and reach maximum values during the summer season. A persistent ∼20% reduction in CO2flux occurred during the Spring of 2017, coincident with the emergence of the area from drought and earthquake swarms in Long Valley Caldera. We used continuous GNSS measurements to calculate seasonal strains and stresses across the Mammoth Mountain area, and resolved resultant stresses onto the Mammoth Mountain Fault, which appears to facilitate gas transport to the surface. The normal stress changes are consistent with seasonal and multiyear changes in CO2flux, suggesting that fault valving by solid earth processes can alter surface gas fluxes.
Possible Anthropogenic Enhancement of Precipitation in the Sahel‐Sudan Savanna by Remote Agricultural Irrigation
Authors: Zeng Yujin , Milly P. C. D. , Shevliakova Elena , Malyshev Sergey , van Huijgevoort M. H. J. , Dunne K. A. 
Published: March 2022

AbstractThe local climatic impacts of historical expansion of irrigation are substantial, but the distant impacts are poorly understood, and their governing mechanisms generally have not been rigorously analyzed. Our experiments with an earth‐system model suggest that irrigation in the Middle East and South Asia may enhance rainfall in a large portion of the Sahel‐Sudan Savanna (SSS) to an extent comparable and opposite to its suppression by other anthropogenic climate drivers during the last several decades. The enhancement arises through a reduction in the meridional gradient of moist static energy from the Sahara Desert to the tropical rainforests. An implication of this study is that remote irrigation is a possible factor affecting the risk of drought and famine and, thus, future water security in the SSS region.
Arctic Snow Depth, Ice Thickness, and Volume From ICESat‐2 and CryoSat‐2: 2018–2021
Authors: Kacimi Sahra , Kwok Ron 
Published: March 2022

AbstractUsing ICESat‐2 and CryoSat‐2 freeboards, we examine the variability of monthly Arctic sea ice snow depth, thickness and volume between October 2018 and April 2021. For the 3 years, satellite‐derived estimates captured a decrease in mean April snow depth (∼2.50 cm) and ice thickness (∼0.28 m) equivalent to an ice volume loss of ∼12.5%. Results show greater thinning of multiyear ice with an end‐of‐season thickness in 2021 that is lower by ∼16.1% (0.50 m), with negligible changes over first‐year ice. For the period, sea ice thickness estimates using snow depth from climatology result in thicker ice (by up to ∼0.22 m) with a smaller decrease in multiyear ice thickness (∼0.38 m). An 18‐year satellite record, since the launch of ICESat, points to a loss of ∼6,000 km3 or one‐third of the winter Arctic ice volume driven by decline in multiyear‐ice coverage in the multi‐decadal transition to a largely seasonal ice cover.
New Findings Relating Tidal Variability and Solar Activity in the Low Latitude MLT Region
Authors: Andrioli V. F. , Xu J. , Batista P. P. , Resende L. C. A. , Da Silva L. A. , Marchezi J. P. , Li H. , Wang C. , Liu Z. , Guharay A. 
Published: March 2022

AbstractMesospheric winds have been measured by meteor radar at Cachoeira Paulista (22.7°S; 45°W) since April 1999. The tidal components were analyzed over about 21 years of available data exhibiting an annual and semi‐annual variation. Amplitudes of meridional diurnal (semidiurnal) tide are on averaged 30% (28%) and the zonal ones are 14% (20%) stronger at solar minimum than at solar maximum. The anticorrelation between F10.7 cm solar flux and amplitudes of the semiannual oscillation of diurnal and semidiurnal tides is presented. Additionally, the sporadic E (Es) layers occurrence has an anti‐correlation with solar activity due to the tidal wind variation. A discussion about the physical mechanism is performed in terms of the particle precipitation during High‐Speed Stream (HSS) events according to the solar cycle. Finally, a superposed epoch analysis of the tidal amplitudes during the HSS events in 2018 is presented. And a slight increase in all tidal components is seen when the structure reached the Earth and in the following days showing that indeed the electron precipitation during HSS events affect the tidal amplitudes.
Uncovering the Controls on Fluvial Bedrock Erodibility and Knickpoint Expression: A High‐Resolution Comparison of Bedrock Properties Between Knickpoints and Non‐Knickpoint Reaches
Authors: Chilton Kristin D. , Spotila James A. 
Published: March 2022

AbstractBedrock erodibility exerts a fundamental control on fluvial incision, and therefore on the evolution of entire landscapes. However, the roles and relative significance of specific bedrock properties like rock strength and discontinuity spacing in setting erodibility remain poorly understood. As a result, erodibility is often overlooked or oversimplified in numerical and field‐based investigations of landscape evolution processes, leading to misinterpretation of channel profile convexities (i.e., knickpoints) in studies seeking to infer uplift or baselevel histories from longitudinal profile analyses. Here, we investigate the controls on fluvial bedrock erodibility and knickpoint expression by conducting detailed surveys of 21 lithologic knickpoints and non‐knickpoint reaches (representing end‐member bedrock erodibility cases) and corresponding bedrock properties from small channels in the south‐central Appalachian Mountains. We use binary logistic regression of field data to test the relative strength of rock strength and discontinuity spacing as predictors of knickpoint occurrence, and therefore their relative impact on fluvial bedrock erodibility. We find that discontinuity spacing more strongly influences bedrock erodibility in this setting, where both rock strength and discontinuity spacing vary widely, confirming for the first time quantitatively the hypothesis that discontinuities exert a dominant control on fluvial erodibility. We also find that knickpoint expression is unique to a given stratigraphic interval, implying that knickpoint morphology is intimately linked to local conditions and therefore effectively unpredictable without detailed field measurements. Finally, because all 21 of our study knickpoints occur within a single geologic unit, our results illustrate that intra‐unit heterogeneity must be accounted for when considering lithologic influence on channel profile convexities.
LOFAR Observations of Lightning Initial Breakdown Pulses
Authors: Liu Ningyu Y. , Scholten Olaf , Hare Brian M. , Dwyer Joseph R. , Sterpka Christopher F. , Kolmašová Ivana , Santolík Ondřej 
Published: March 2022

AbstractThis paper reports an observational study of lightning initial breakdown pulses (IBPs) using the low‐frequency array radio telescope and a broadband magnetic field sensor. The data show that the overall spatiotemporal evolution of the electrical breakdown causing an IBP is rather complex. During an IBP, spatially and temporally separated bursts of very high frequency (VHF) electromagnetic radiation occur in a volume on the order of 1003 m3, and they are coincident with brief magnetic field pulses, indicating that the location of the active breakdown region can change suddenly. Furthermore, recurrent breakdown activity is observed, especially at the location of the VHF burst. Interpreting each VHF burst as being generated by a corona burst, an IBP pulse appears to start off from an initial corona burst and subsequent corona bursts enhance it. We further suggest that the generation of IBPs likely involves multiple space stems/leaders and connections between them.
Glacier Surface Speed Variations on the Kenai Peninsula, Alaska, 2014–2019
Authors: Yang Ruitang , Hock Regine , Kang Shichang , Guo Wanqin , Shangguan Donghui , Jiang Zongli , Zhang Qibing 
Published: March 2022

AbstractTo characterize the spatiotemporal variations of glacier surface speed on the Kenai Peninsula, Alaska (∼3,900 km2), we derived 92 surface speed fields between October 2014 and December 2019 using intensity offset tracking on Sentinel‐1 data. On average, speeds are 50% greater in spring (March‐May) than the annual mean (69 m a−1) while winter speeds are close to the annual mean. While marine‐terminating glaciers have their maximum speed near the terminus, both land‐ and lake‐terminating glaciers flow fastest around the median glacier elevation. On average, the lake‐terminating and tidewater glaciers flow 1.7 and 2.3 times faster than the land‐terminating glaciers, respectively. Monthly variations over the 5‐year period are strikingly synchronous regardless of terminus type suggesting that regional‐scale meteorological drivers govern the temporal variability. Mean annual speeds fluctuate roughly ±10% of the period mean without an apparent trend. At lake‐terminating Bear Glacier, a short‐term tripling in ice speed in fall 2019 over the area below an ice‐dammed lake coincides with an observed glacier lake outburst flood (GLOF). An earlier GLOF caused a persistent breach of the beach barrier between the proglacial lake and ocean which likely led to overall speed‐up of the lower glacier part throughout 2019. A significant speedup was also observed at the lower part of the lake‐terminating Ellsworth Glacier and attributed to rapid glacier retreat and lake expansion, probably further amplified by the terminus area becoming buoyant and a large tabular iceberg breaking off. Our results highlight the impact of GLOFs and proglacial characteristics in spatial and temporal glacier speed variations.
SIAH1 reverses chemoresistance in epithelial ovarian cancer via ubiquitination of YBX-1
Authors: Gao Wujiang , Chen Lu , Lin Li , Yang Meiling , Li Taoqiong , Wei Hong , Sha Chunli , Xing Jie , Zhang Mengxue , Zhao Shijie , Chen Qi , Xu Wenlin , Li Yuefeng , Zhu Xiaolan 
Published: March 2022

AbstractChemoresistance is a severe outcome among patients with epithelial ovarian cancer (EOC) that leads to a poor prognosis. YBX-1 has been shown to cause treatment failure and cancer progression in EOC. However, strategies that directly target YBX-1 are not yet conceivable. Here, we identified that SIAH1 which was downregulated in chemoresistant EOC samples and cell lines functioned as novel E3 ligases to trigger degradation of YBX-1 at cytoplasm by RING finger domain. Mechanistic studies show that YBX-1 was ubiquitinated by SIAH1 at lys304 that lead to the instability of its target m5C-modified mRNAs, thus sensitized EOC cells to cDDP. Overexpression of SIAH1 enhanced the antitumor efficacy of cisplatin in vitro and in vivo, which were partially impaired by ectopic expression of YBX-1 or depletion of YBX-1 ubiquitination. In summary, our data identify the SIAH1/YBX-1 interaction as a therapeutic target for overcoming EOC chemoresistance.