bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors affecting mortality in Pediatric Severe Head Injury
Authors: ÖZCAN Serhan , BOZKURT İrem , AKAY Seçil , PERK Oktay , UYAR Emel , DEMİRCİ Harun , ÖZIŞIK Pınar 
Published: August 2022

Aim: It is aimed to determine the factors affecting mortality in pediatric patients followed up with severe traumatic brain injury in the pediatric intensive care unit.
Material and method: All patients followed up in the Pediatric Intensive Care Unit between April 2019 and April 2021 due to severe traumatic brain injury were included. Demographic characteristics, pre-intensive care interventions and imaging findings, treatments applied in intensive care and intervention information of all patients were collected. Results were evaluated as survival rate, presence of tracheostomy requirement, brain death, and Pediatric Cerebral Performance Scale at discharge. The patients divided into two groups as survivors and non-survivors. All obtained data were compared between the two groups.
Results: During the study period, 47 patients with a diagnosis of severe traumatic brain injury were followed up. It was observed that the requirement of cardiopulmonary resuscitation, the need for inotrope-vasopressor and the need for erythrocyte transfusion were statistically significantly higher in the non-survivor group. (p value, respectively: 0.001, 0.001, 0.001) The survival rate in all patients in the study group was 70.2%. In non-survivor group most common pupil response at admission was fixed-dilated (71.4%). In non-survivor group 60% of the patients were lost in the first 24 hours of intensive care.
Conclusion: Mortality increases in patients who need resuscitation, erythrocyte transfusion and inotrope before intensive care. Patients who died showed pathologic pupillary response and low GCS. Severe TBH patients died mostly in first 24 hours of admission.
Advanced wound healing with application of products with diversified propolis
Authors: Rodriguez Claudia , Marichal Adrian , Ramos Adrián , Burguez Carla 
Published: August 2022

In the understanding that we have in our country the industry and the raw material of elaboration of products derived from propolis, based on the evidence published in scientific articles that refer to the anti-inflammatory activity of propolis which is linked to the ability of its constituent polyphenols (flavonoids and aromatic acids) to inhibit NF-kB (nuclear transcription factor kappa-b) and reducing the levels of inflammatory mediators, this produces a decrease in inflammation, pain and microbial load, it is then that for this reason it was decided to clinically verify the efficacy of this product in complex wounds by conducting a descriptive, prospective cross-sectional study.
La resiliencia de los productores y empresarios turísticos ante los fenómenos climatológicos en la Comunidad de Cahuita de Limón de Costa Rica
Authors: Vásquez Kattia Lizzett Vasconcelos 
Published: August 2022

Este documento pertenece a uno mayor donde se presentan los primeros resultados de la cantidad de fenómenos naturales que han estado presentes en la Región Caribe del país y su afectación en los empresarios turísticos de Cahuita. Cabe indicar que la Región Caribe tiene una posición geomorfológica e hidrológica que favorece a la llegada de fenómenos climatologicos. En esta zona las personas se dedican a diferentes tipos de cultivos como: las musáceas (diferentes tipos de plátano, banano, guineo, etc.), el cacao, raíces tropicales (yuca, y otros tubérculos), frutas propias del lugar (por el clima). Además, estos productores son los proveedores de las empresas turísticas tales como: hoteles, restaurantes, sodas y otros negocios asociados al turismo), siendo la principal fuente de ingreso de la comunidad, por la ubicación estratégica con el Parque Nacional Cahuita que se crea por el Decreto Ejecutivo No. 1236-A, del 7 de septiembre de 1970. El objetivo es “Establecer los fenómenos climatológicos a los que se exponen los productores y empresarios turísticos para la resiliencia y adaptación del territorio en su gestión durante el periodo 1800-2021”. La metodología es de estudios de casos y el enfoque holístico. Los datos se recogen por medio de la solicitud formal de las bases a la Comisión Nacional de Emergencias, los informes a la Municipalidad de Talamanca y una visita con una guía de observación a los empresarios turísticos de Cahuita. La población participante es de 96 personas de la comunidad de Cahuita. Se triangulan los datos de las instituciones y de las 96 personas en total. Los resultados más representativos son la comunidad de Cahuita tiene la afectación más de 40 eventos naturales que son: inundaciones por crecida de ríos (llenas como le dicen las personas de la zona) y lluvias por la llegada de Ondas Tropicales, deslizamientos en la localidad y lugares cercanos. En algunos casos los productores haber pedido todo lo material, han recomenzado, reconstruyendo sus casas de habitación, los productores, retoman sus parcelas (fincas), vuelven a sembrar sus productos y salen adelante. En el caso de los empresarios turísticos han reinventado sus negocios, reacondicionado sus hoteles, restaurantes considerando medidas preventivas.
Aspectos de imagem do Angiossarcoma primário da mama: um relato de caso
Authors: Salgado Bravo Ana Clara , Sias Frinhani Cissielly , Povill Jéssica Gonçalves , Da Costa Geraldino Ana Clara 
Published: August 2022

O angiossarcoma de mama é um tumor maligno de origem endotelial vascular extremamente raro. A apresentação clínica mais característica é uma massa mamária palpável e indolor, com coloração violácea/azulada da pele sobrejacente. O seu diagnóstico é estabelecido através da análise histopatológica da peça adquirida através de core biópsia ou biópsia excisional. Os aspectos de imagem são variados e têm grande relevância para o diagnóstico, estadiamento e acompanhamento de resposta terapêutica. Relatamos um caso de uma paciente de 59 anos, apresentando nódulo palpável na mama esquerda, com crescimento há 8 meses e leve coloração arroxeada na topografia do nódulo. Foram realizados exames de imagem para avaliação das características da lesão por mamografia digitalizada, ultrassonografia e Ressonância Magnética (RM).
Clinical Prediction of Acetylator Phenotype in Tuberculosis Patients on Medicare using Blood Group
Authors: MAIRIGA J. P. , UKEAGBU M.C. , AMBI L. J. 
Published: August 2022

ABSTRACT
Individual acetylation phenotype detected by metabolic phenotyping tests using a number of surrogate drugs, such as isoniazid is time consuming. The aim of this work was to determine the clinical prediction of acetylator phenotype in tuberculosis patients on medicare using blood group. 150 Tuberculosis patients (102 males and 48 females) on medicare were examined using urinalysis technique for acetylator status and tile method for blood group analysis. The result of the acetylator phenotypes revealed that 46.7% were fast acetylators while 53.3% were slow acetylators. The highest frequency of fast acetylators were subjects with blood groups O+ve and A+ve. Similarly, the highest frequency of slow acetylators were observed in blood groups B+ve and O+ve. Blood groups AB-ve and B-ve formed the lowest frequency of fast acetylators while A-ve and AB-ve formed the lowest percentage of slow acetylators respectively. Analysis of the blood groups and the acetylator phenotype using Pearson’s correlation showed a significant (p < 0.01) relationship with a coefficient of 0.852; between the blood groups of M.Tb patients and the fast and slow acetylators (p < 0.05, with a coefficient of 0.76) respectively. We imply that for standard TB treatment, more treatment time be considered for subjects with blood groups that are predominantly fast acetylators (e.g., O+ve ) and close monitoring through the treatment period for predominantly slow acetylators (e.g B+ve). Further study on the serum concentration of each blood group for the drugs and molecular analysis of the blood phenotypes is advocated.
reby recommended.
Screening For Phenylthiocarbamide Taste Sensitivity Response Status On Apparently Healthy Subjects: A Pilot Study
Authors: MAIRIGA J. P. , Iroanya O O. , Yahaya T.O. 
Published: August 2022

The dynamics of studying genetic variation in human population using phenylthiocarbamide has contributed immensely in influencing our knowledge of variations and diversity globally. The pilot study aims to screen for the taste sensitivity response status using different concentrations of a stock solution of 0.10% phenylthiocarbamide. 232 subjects were randomly recruited using a drawn questionnaire. 84.9% were tasters while 15.1 % were non-tasters. Of the 133 males, 52.3% were Tasters while 85.7% were non-Tasters. The 99 females, constituted 47.7% Tasters and 14.3% non-tasters. The Chi-Square analysis on gender was significant p-<0.000. The result of the different age range showed a decrease in the population of tasters with increase in age and a reverse among non-tasters. The phenotypic status of the age range of subjects was not significant p> 0.433. The combined allelic frequency of tasters and non - tasters was 0.61 and 0.39. Similarly, the individual allelic frequencies of male and female tasters were 0.52 and 0.78 while male and female non-tasters were 0.48 and 0.22, respectively. The pooled homozygous and heterozygous outcome for males was the same (0.50), but females were 0.66 and 0.34. The homozygous and heterozygous outcome of the combined population was 0.52 and 0.48. The highest cases of tasters were recorded at a threshold of 0.025 and 0.50 with female subjects responding most. The study provides insight to the distribution of the Phenylthiocarbamide phenotype, the heterozygous, homozygous and allelic frequencies of the population, which may serve as an index for directing dietary choice or diagnoses by health care professionals.
The Application of Whole Genome Sequencing in Medical and Pharmaceutical field
Authors: Awofisayo Oladoja , Eseyin O.A 
Published: August 2022

W
Whole Genome Sequencing (WGS) is a high throughput process utilized to obtain the nucleotide bases that constitutes a genome. The Sanger Technique was used to sequence the first human genome; however the limitations include inability to sequence more than few genes per time and it cannot detect structural rearrangement. The method also has far reaching cost implications. The New Generation Sequencing Platform has further lend credence to WGS, as sequencing can be carried out in a shorter period of time with accuracy hence a great improvement in the clinical setting for diagnostic purposes. This also needs to correspond with effective data analysis and interpretation. This method has proved useful as it can be used to compare bacterial strains that have a divergence at one nucleotide base, transmission, Virulence, phenotypic characteristics can be deduced. Various strains can be analyzed via a single process and it is an essential tool in clinical diagnosis and in monitoring the outbreak of a new disease. This is important in handling multidrug resistance strains of bacteria. In addition, it equally helps in the identification of drug response markers on drug target. Moreover, drug metabolism or disease pathway can enhance development of drug tailored to specific individuals for specific purposes, hence the ability to define a population genetically.
Development of SageMath filter for Moodle
Authors: Modlo E. O. , Semerikov S. O. 
Published: August 2022

Research goals: determine the characteristics of the development process, installation, configuration and usage of the filter SageMath for learning support system Moodle.Research objectives: to prove the feasibility of using Moodle system as a tool to support the process of competency formation in technical objects simulation of future bachelors in electromechanical engineering; to analyze existing support tools of technical objects simulation and to identify the ways of it’s integration into Moodle; to describe the structure and features of the software implementation of the new SageMath filter for Moodle; to provide the guidance on installing and configuring developed filter; to describe the examples of filter usage.Research object: computer mathematics and learning support systems integration.Research subject: text filter development process for learning support system Moodle to processing the commands of computer mathematics system SageMath.Research methods used: analysis of state educational standards and existing application, software engineering process.Research results. Designed SageMath filter allows to execute the Sage code on the external SageMathCell public server, to view the execution results at the Moodle pages without reloading by using AJAX technology, to stave off XSS attacks and ready for use with Moodle.The main conclusions and recommendations:1. The perspective direction of learning environment development for bachelors in electromechanical engineering is the integration of learning support system Moodle and computer mathematics system SageMath.2. An effective tool for embedded a computer mathematics systems SageMath models into Moodle is a text filter. The software engineering process for this filter is presented in the article.3. Promising area of future research is the use of a developed filter in the process of bachelor’s in electromechanical engineering competencies in technical objects simulation by embedding into Moodle learning courses the interactive labs programmed in Sage.
HUBUNGAN PERSEPSI KINESTETIK, PANJANG TUNGKAI DAN POWER OTOT TUNGKAI TERHADAP AKURASI SHOOTING PEMAIN FUTSAL BERSAMA FS MEDAN TAHUN 2021
Authors: Tanjung Hasbi Latif , Supriadi Amir 
Published: August 2022

The purpose of this study is to find out the relationship of kinesthetic perception with accuracy along with the length of limbs and muscle power limbs in shooting futsal players together with FS Medan so that evidence is obtained based on scientific rules and guidelines. This type of research is correlational using descriptive research methods with test and measurement techniques. The population in this study is all Futsal players in Club Bersama FS Medan with total sampling techniques so that the samples in this study are 10 futsal athletes with FS Medan. The research data was obtained based on analysis with simple correlation statistical analysis techniques. Based on the analysis of data, description and testing of the results of the study, it was obtained that (1) There is a significant relationship between kinesthetic perception and accuracy of ball shooting in futsal games of the players clubFS Medan Year 2021withrcount0,956 > rtable (n-2) 0,6319 with significant value (P) = 0,000 <0,05 (2) There is a significant relationship between the length of limbs and the accuracy of shooting balls in futsal games of players club FS Medan Year 2021withrcount0,846 > rtable (n-2) 0,6319 with significant (P) = 0,002 <0,05. (3) There is a significant relationship between limb muscle power and the accuracy of shooting balls in futsal games of players club FS Medan Year 2021 with rcount0,806 > rtable (n-2) 0,6319 with significant value (P) = 0,005 <0,05 (4) There is a significant relationship between kinesthetic perception, length of limbs, limb muscle power and the accuracy of shooting balls in futsal games of players club FS Medan Year 2021 with rcount0,975> rtable (n-2) 0,6319 with significant value (P) = 0,000 <0,05 Based on these results, it can be concluded that to create accuracy of shooting can not be separated from three factors namely kinesthetic perception, length of limbs and limb muscle power.
Wellbeing Profile of France and India IT Employees: A Cross‐Cultural Study
Authors: Papillon Pascal 
Published: August 2022

Background: Cultural influence and variances have a great influence in the development of psychosocial well-being. Cross-cultural psychologists explore the difference between Eastern and Western cultures. The present study was designed to analyse the variations in wellbeing profile of IT professionals between India and France.
Methodology: Two hundred and Fourteen non-probabilistic samples were recruited via various IT companies from France (n=92) and India(n=122). The participants completed the wellbeing profile consisted of Freiburg Mindfulness Inventory, Subjective Fluctuating Happiness Scale and Subjective Authentic-Durable Happiness Scale (SFHS and SA-DHS) and rating scale for Satisfaction at work, importance of religions/spirituality shared through a digital format, built on the Google Form.
Results: Based on independent-samples t-tests, the results indicated that Indian and French IT professionals did not exhibit a difference on levels of Mindfulness, Satisfaction at work, Fluctuating Happiness and Authentic-Durable Happiness. In addition, the findings shown inter correlations between Mindfulness, Satisfaction at work, Fluctuating Happiness and Authentic-Durable Happiness across the culture. In contrast, the results indicated that Indian IT professionals did exhibit higher levels in importance of Religions and Spirituality when compared to French IT professionals.
Conclusion: In a nutshell, the present study came to the conclusion that Indian and French employees share a greater number of wellbeing characteristics in common. Religion and spirituality are also important parts of the Indian culture of well-being.
Sexual Practice and Perception of HIV/AIDS And Health Seeking Behaviour Among Men Who Have Sex with Men in Hyderabad
Authors: Nalla Krishna , Maktha Vijay kumar , Bommi Bhanuja Rani , Gokul Vinod Kumar 
Published: August 2022

Introduction: The Men who have Sex with Men (MSM) are a vulnerable population and need special attention in fight against the HIV/AIDS. The HIV trend has been an increasing trend among MSM. Study was done to determine the factors influencing sexual practice, perception of HIV/AIDS and Health seeking behavior among MSM in Hyderabad.
Methodology: This was a facility based cross sectional study undertaken in the Targeted Intervention sites in Hyderabad, Telangana. A total of 300 Men who have Sex with Men who are above 18 years of age and registered were included. All the MSM visiting the TI centres during the study period were interviewed personally in their local language by using a pre-designed, pre-tested, semi structured and pre-coded proforma.
Results: Mean age was 27.68 years. Majority of participants 119(39.66%) had their first sexual encounter at the age of 15-17 years. 130 (43.33%) visited the Target Intervention centres 1-2 times during the last month. About half of the participants i.e, 141(47.00%) belongs to Kothi Group and most of the MSM i.e, 198(66.00%) used condom during the sex with male last time.
Conclusions: Stigma and cultural intolerance of same-sex relations are often largely to blame for rising epidemics, and until these issues are addressed it will be difficult to make headway in reducing HIV infection levels among MSM - which, in turn, will hinder the wider global efforts to manage HIV and AIDS.
Predictors Of Catastrophic Costs Of Tuberculosis (TB) Among Patients Co-Affected With TB-HIV And TB-Diabetes In Bhavnagar Region, Western India
Authors: Rupani Mihir , Vyas Sheetal 
Published: August 2022

Background: By the year 2030, no family with a patient of tuberculosis (TB) is supposed to incur catastrophic costs. In India, a significant number of people suffer from TB, and many face catastrophic costs. Our objective was to determine the predictors of catastrophic costs due to TB among co-prevalent TB-HIV and TB-diabetes patients.
Methods: We conducted a cross-sectional study among 234 patients co-affected with TB-HIV and 304 patients with TB-diabetes co-prevalence in the Bhavnagar region (western part of India). TB costs, estimated using a validated questionnaire, were defined to be catastrophic when they exceeded 20% of annual household income. Multivariable logistic regression was used to determine the significant predictors of catastrophic costs of TB.
Results: Four percent of patients in each group incurred catastrophic costs due to TB. Female gender [adjusted odds ratio aOR 6 (95% CI 1.2-33)], being single [aOR 9 (95% CI 1.5-52)], low socioeconomic status [aOR 7 (95% CI 1.2-30)], private consultation for TB [aOR 9 (95% CI 1.5-53)], and hospitalization in first HIV visit [aOR 19 (95% CI 3-137)] significantly predicted catastrophic costs of TB among patients co-affected with TB-HIV. Among patients with TB-diabetes co-prevalence, hospitalization in first TB visit [aOR 7 (95% CI 2-29)], and private consultation for TB [aOR 7 (95% CI 1.6-30)] were the significant predictors.
Conclusions: Despite a lower percentage of TB-HIV/ TB-diabetes patients facing catastrophic costs, hospitalization and private care-seeking are the “modifiable” determinants of TB catastrophic costs in our study setting.
Análisis Situacional de la desnutrición infantil a nivel de Latinoamérica.
Authors: Durán Pincay Yelisa Estefanía , Andrade Santos Raysha Michell , Aveiga Bartolomé Yaritza Lissethe , Molina Zambrano Dayana Suyin 
Published: August 2022

Los niños se encuentran especialmente en riesgo para padecer desnutrición, a causa del alto costo proteico y energético del crecimiento, cualquier deficiencia de nutrientes llega a afectar el desarrollo, si ocurre un retraso es probable que exista la presencia de alguna enfermedad subyacente, la identificación oportuna de niños en riesgo de desnutrición es indispensable para brindar un control y apoyo nutricional adecuado para prevenir la desnutrición nivel global. Es un problema que afecta gravemente a las sociedades de ingresos medianos y bajos, la situación prevalente y grave, en Latinoamérica se refleja una disminución en las tasas de desnutrición infantil, en Ecuador este problema afecta a dos niños de cada cinco, el objetivo principal de esta investigación es realizar un análisis situacional sobre la desnutrición infantil a nivel de Latinoamérica, para lo cual se utilizó una metodología de revisión sistemática documental científico. Dentro de los resultados obtenidos se evidencio que existe una gran prevalencia de la desnutrición aguda infantil, a nivel de Latinoamérica este estado es muy persistente en aquellos menores de cinco años y que viven en lugares pobres, cuyas familias tienen ingresos inferiores. En conclusión, la desnutrición infantil representa en gran escala la mitad o una buena parte de las muertes en niños a nivel mundial, tomando en consideración los perjuicios que deja, es de gran necesidad vigilar estos casos de desnutrición infantil.
WEBINAR PENGGUNAAN JAMINAN KESEHATAN NASIONAL (JKN) DI MASA PANDEMI COVID 19
Authors: Gusti Agung Sri Guntari  , Ni Putu Eka Febianingsih  , Putu Ratna Suprima Dewi  
Published: August 2022

The National Health Insurance (JKN) Program is part of the National Social Security System (SJSN) which is organized using the principle of mandatory social health insurance based on Undang-Undang Republik Indonesia Nomor 40 Tahun 2004. The implementation of the National Social Security System aims to provide guarantees for the fulfillment of the basic needs of a decent life for each participant and their family.
In the use of JKN services, participants are required to follow the referral service procedures as stated in the regulations. During the Covid-19 pandemic, various service channels have been launched which are expected to make it easier for participants when they want to take advantage of the JKN program. So it is felt necessary to socialize to the community to understand the benefits and procedures of JKN services so that this program can be utilized as well as possible.
This community service activity is carried out by providing education to private workers in Gianyar Regency. Education is carried out in the form of online webinars by utilizing zoom meeting media. After socialization, the results were obtained that there was an increase in participants' knowledge of JKN.