bluuebunny/crossref_metadata_2025_split huggingface dataset:
International competitive landscape of administrative intelligent decision-making theory and application: knowledge graph analysis based on literature and patent
Authors: Huang Xin , Peng Yuxing , Li Jianfei , Zhu Guiju , Peng Han 
Published: February 2025

PurposeThis article aims to elaborate on the current relevant policies, research literature and technical applications of administrative intelligent decision-making in major countries in the world, to summarize the current focus areas of international competition in administrative intelligent decision-making and to provide references and insights for other countries.Design/methodology/approachThe knowledge graph tool CiteSpace was used to conduct a quantitative analysis of the field of administrative intelligent decision-making, using the two dimensions of research literature and technology patents to analyze the basic status and evolution process of artificial intelligence applied to administrative decision-making.FindingsOver the past 30 years, theoretical research on administrative intelligent decision-making has primarily centered on countries like the United States of America, China and Japan. The main themes include leveraging artificial intelligence (AI) technology to enable digital government transformation, enhance administrative efficiency and promote public value through service-oriented initiatives. Countries like South Korea, China and the United States of America have demonstrated significant advantages in technology development and patent applications, focusing on e-government systems, intelligent government auditing, addressing policy mismatches between supply and demand and integrating online and offline administrative services. The international competitive landscape in this field is shaped by three key factors: foundational theories, technological advancements and practical scenario applications.Originality/valueDespite the rapid advancements in AI technology and the acceleration of enterprise digital transformation, discussions on the intelligent transformation of administrative decision-making leveraging next-generation information technology remain limited. This study summarizes the development trajectory of administrative intelligent decision-making in major countries worldwide, analyzes the international competitive landscape of its theoretical and application research and highlights key focus areas. These findings offer valuable insights for advancing the construction of administrative intelligent decision-making systems in other nations.
Blockchain concepts in business research – a scoping review
Authors: Cîmpan Ioana , Crișan Emil Lucian 
Published: February 2025

PurposeThe purpose of this paper is to provide a condensed perspective of blockchain-related concepts for business researchers and practitioners, amid the growing popularity of the subject.Design/methodology/approachThis paper is a literature review following the Preferred Reporting Items for Systematic reviews and Meta-Analysis Extension for Scoping Reviews methodology. We have revised 42 papers that have detailed concepts such as blockchain, Web 3.0, blockchain types, affordances, and limitations.FindingsThe paper creates a comprehensive overview of blockchain-related concepts. It starts by looking at the blockchain's various definitions and explains the technology's novelty. The components and the process of making a transaction in the blockchain are explained from a combined paradigm, including both business and technological concepts. Further on, the paper discusses the existing types of blockchain, together with the affordances provided by the usage of the technology. The last part includes the limitations of blockchain.Originality/valueThe present study reveals the existence of three paradigms while studying the subject: business-centric, technological-centric, and combined. While the primary aim of this research is to explain concepts for business researchers and practitioners, it includes technological aspects as well, therefore, aligning with the combined paradigm.
Health tourism in Hungary: future challenges for thermal spas
Authors: Smith Melanie Kay 
Published: February 2025

PurposeThis article identifies some of the challenges facing health tourism development in Hungary and uses research with expert respondents to make recommendations for the sector.Design/methodology/approachA combination of literature review, recent statistics and Delphi study data involving health tourism experts is used to identify challenges in product and service development which affect customer satisfaction.FindingsSpas need to concentrate on improving their infrastructure where funding allows and to create better quality products and services that are tailored and marketed to specific segments. Investment may also be needed in staff recruitment and training to overcome shortages.Originality/valueNew insights are provided into the current situation in Hungarian health tourism using a comparative study of V4 countries. This helped to identify common challenges and solutions.
A test of operational sex ratio theory across latitudes reveals temporal variation in sex‐specific behavioural reaction norms
Authors: Martinossi‐Allibert Ivain , Wacker Sebastian , Aparicio Estalella Claudia , Kvarnemo Charlotta , Amundsen Trond 
Published: February 2025

Abstract

Predicting the strength and direction of sexual selection is a challenge, as the effects of ecological factors, social environment and behavioural plasticity all need to be considered. The operational sex ratio (OSR) is a key variable, which has been shown to (i) affect the strength and direction of mating competition, as a social environment cue, and (ii) be affected itself by ecological conditions through sex‐specific environmental effects. Gaining a global view of (i) and (ii) in wild populations represents a necessary step for our understanding of sexual selection dynamics in the wild. Here, we address this challenge within the reaction norm framework.

We conducted an extensive field study on the two‐spotted goby Pomatoschistus flavescens, monitoring six populations along a latitudinal gradient during an entire breeding season. We compared the temporal trajectories in social environment and sexual displays across populations, which is unprecedented.

Using a reaction norm framework based on OSR theory, we show that what appears to be great variation in sexual displays across populations and sampling times, follows consistent rules. Sexual display behaviour followed behavioural reaction norms in response to the social environment that were consistent across populations, but social environment fluctuations were specific to each population.

Recording behaviour not only over time, but also along a latitudinal gradient where ecological conditions vary and in turn affect OSR, was necessary to reveal the relationship between social environment and sexual displays, which in turn contributes to sexual selection dynamics.
Honeybees interfere with wild bees in apple pollination in China
Authors: Li Jingwei , Olhnuud Aruhan , Tscharntke Teja , Wang Meina , Wu Panlong , Xu Huanli , Liu Yunhui 
Published: February 2025

Abstract

Honeybees (Apis mellifera) are increasingly used in commercial crop production, while wild bees are also important pollinators. Few studies have investigated the relative importance of honeybees and wild bees for apple pollination and whether the contribution of wild bees is affected by increasing numbers of honeybees.

Here, we conducted experiments in 52 commercially important Fuji apple orchards across three apple production areas in China, to investigate how wild bees, honeybees and their interaction influences apple quantity (fruit set, weight) and quality (seed number). Both honeybees and wild bees contributed to apples production, resulting in an overall 996%, 26% and 64% increase of apple fruit set, fruit weight and seed number, respectively.

We found a hump‐shaped relationship between bee density and fruit set and fruit weight with the maximum fruit set at intermediate bee density, but honeybees reached the maximum only with one and a half times higher numbers than wild bees. Furthermore, when honeybee activity density was low, an increase in wild bee activity density and species richness led to enhanced pollination contribution. Conversely, when honeybee activity density was high, increased wild bee activity density and species richness were associated with reduced pollination contribution. Additionally, the highest fruit set was observed at high densities of wild bees and intermediate densities of honeybees. These results indicate that high honeybee activity density may interfere with the pollination services provided by wild bees in apple orchards.

Synthesis and applications. Both honeybees and wild bees contribute to apple pollination and production, but wild bees evidenced much higher pollination efficiency than honeybees. Importantly, introducing high density of honeybee colonies appeared to enhance competition with wild bees, decreasing their contribution to pollination. As highest fruit set was found with high wild bee densities, but only intermediate levels of honeybee densities, it is important to carefully assess the number of honeybee colonies before possible introduction of hives for apple production, in particular when wild bee diversity and density are high. Conserving wild bee diversity is of priority to harness pollination services in apple production, given their high diversity and pollination efficiency.
Thawing frozen foods: A comparative review of traditional and innovative methods
Authors: Çalışkan Koç Gülşah , Özkan Karabacak Azime , Süfer Özge , Adal Samiye , Çelebi Yasemin , Delikanlı Kıyak Berrak , Öztekin Sebahat 
Published: February 2025

AbstractDue to the changing consumer lifestyles, the tendency to adopt foods that require less preparation time and offer both variety and convenience has played a significant role in the development of the frozen food industry. Freezing is one of the fundamental food preservation techniques, as it maintains high product quality. Freezing reduces chemical and enzymatic reactions, lowers water activity, and prevents microbial growth, thereby extending the shelf life of foods. The freezing and thawing procedures directly impact the quality of frozen foods. The degree of tissue damage is determined by the freezing rate and the structure of the ice crystals that form during the freezing process. Generally, thawing occurs more slowly than freezing. During thawing, microorganisms, as well as chemical and physical changes, can cause nutrient damage. Thus, the goal of this review is to identify innovative and optimal thawing strategies. In order to save energy and/or improve quality, new chemical and physical thawing aids are being developed alongside emerging techniques such as microwave‐assisted, ohmic‐assisted, high pressure, acoustic thawing, and so on. In addition to discussing the possible uses of these technologies for the thawing process and their effects on food quality, the purpose of this study is to present a thorough comparative overview of recent advancements in thawing techniques.
Environmental conditions and nutritional quality of vegetables in protected cultivation
Authors: Gruda Nazim S. , Samuolienė Giedrė , Dong Jinlong , Li Xun 
Published: February 2025

AbstractDespite progress in reducing global hunger, micronutrient deficiencies and imbalanced diets linked to urbanization remain pressing health threats. Protected cultivation offers a promising avenue for sustainable intensification of vegetable production. Additionally, indoor and vertical farming have recently emerged as cutting‐edge strategies, particularly in densely populated urban areas and mega‐cities. However, research has focused on maximizing yield, neglecting the impact of pre‐harvest conditions on produce quality. Here, we explore strategies for manipulating environmental factors within protected cultivation systems to enhance vegetable nutritional value. Research suggests moderate stress can positively influence nutrient composition while plants exhibit stage‐specific metabolic responses to environmental factors. For instance, seedlings thrive under a higher blue‐to‐red ratio, while green light benefits leafy vegetables. Additionally, increased blue light or supplemental UV‐A benefits flowering and fruiting vegetables. When other environmental factors are optimal, light intensity significantly impacts vegetable nutritional quality, followed by CO2 levels, light spectrum, temperature, and humidity. Further research is needed to fully understand the mechanisms, the complex interplay of environmental factors, and their interaction with genetic material and cultural practices on nutritional quality.
The role of hyperuricemia in the progression of end‐stage kidney disease and its molecular prospective in inflammation and cardiovascular diseases: A general review
Authors: Waheed Yousuf Abdulkarim , Liu Jie , Almayahe Shifaa , Sun Dong 
Published: February 2025

AbstractWith the ongoing development of the Chinese economy, the occurrence of chronic kidney disease (CKD) has experienced a remarkable upsurge recently, and due to uremia caused by CKD, the number of patients undergoing dialysis has shown a dramatic increase. China has been ranked first in the world for patients undergoing hemodialysis (HD) and peritoneal dialysis (PD) with approximately one million patients across the country. Due to the loss of kidney function caused by CKD, the kidneys tend to lose their ability to excrete uric acid (UA) out of the body; therefore, most patients undergoing dialysis are complicated with hyperuricemia (HUA). HUA is an abnormal disease of purine metabolism, and it's considered a chronic disease. More than 90% of patients suffering from HUA will not show any symptoms on physical examination. According to statistics, if high serum UA is left untreated, 55% of patients will develop severe problems due to the purine crystallization in the body, and the kidneys are the most affected organs by HUA causing renal insufficiency that can promote end‐stage kidney disease (ESKD) by activating the renin‐angiotensin system (RAS), which will lead to inflammation, arteriosclerosis, cardiovascular diseases (CVD), and other diseases. Lifestyle modifications and pharmacological interventions are the first primary choice for lowering UA, although dialysis will tend to reduce the high UA levels in the blood, drugs are also necessary. This review will summarize the mechanisms and metabolism of UA, the relationship between HUA and ESKD progression, HUA and inflammation, HUA and CVD, and pharmacological treatment of HUA.
Neglected Human Risk Factors Determining Sustainable Health by Microbial Causes: Individual Versus Social Conducts, Scientific Versus Stultified Behaviour
Authors: Baquero Fernando 
Published: February 2025

ABSTRACTMicrobes constitute a ubiquitous warp, a highly sensitive skin of the biosphere that can be scratched and damaged by all human activities. However, the existence of life in general and the human species, in particular, depends on the intelligent preservation of such a biological microbiological cement linking our health with the health of Earth. We are responsible for maintaining sustainable health by managing our damaging individual and social behaviour, and we are also charged with the duty of correcting the microbial disequilibrium we are provoking. The harmful secondary effects resulting from the nature of the species Homo sapiens are frequently neglected. However, sustainable health by microbial causes depends on our individual and social psychology. The role of individual psychology, social behaviour (including the ‘tragedy of the commons’), based on collective psychology, culture, values and social norms, and the influence on sustainable health of the methodology of research and management of interventions are briefly analysed. As a general antidote to our unavoidable natural stultified behaviour, education in science is the only possibility to counteract mistakes and restore human dignity.
Cerebral Small Vessel Disease Outperforms Brain Atrophy as an Imaging Biomarker in Diabetic Retinopathy
Authors: Shen Xinyi , Zhang Wen , Li Xin , Zhang Xin , Li Qian , Wu Min , Fu Linqing , Lu Jiaming , Zhu Zhengyang , Zhang Bing 
Published: February 2025

ABSTRACTAimThis study aimed to examine microvascular lesions and neurodegenerative changes in diabetic retinopathy (DR) compared to type 2 diabetes mellitus (T2DM) without DR (NDR) using structural MRI and to explore their associations with DR.Methods243 patients with NDR and 122 patients with DR were included. Participants underwent conventional brain MRI scans, clinical measurements, and fundus examinations. Cerebral small vessel disease (CSVD) imaging parameters were obtained using AI‐based software, manually verified, and corrected for accuracy. Volumes of major cortical and subcortical regions representing neurodegeneration were assessed using automated brain segmentation and quantitative techniques. Statistical analysis included T‐test, chi‐square test, Mann–Whitney U test, multivariate analysis of variance (MANCOVA), multivariate logistic regression, area under the receiver operating characteristic curve (AUC), and Delong test.ResultsDR group exhibited significant differences in 11 CSVD features. Meanwhile, DR showed an atrophy trend in the frontal cortex, occipital cortex, and subcortical gray matter (GM) compared to NDR. After adjustment, DR patients exhibited greater perivascular spaces (PVS) numbers in the parietal lobe (OR = 1.394) and deep brain regions (OR = 1.066), greater dilated perivascular spaces (DPVS) numbers in the left basal ganglia (OR = 2.006), greater small subcortical infarcts (SSI) numbers in the right hemisphere (OR = 3.104), and decreased left frontal PVS (OR = 0.824), total left DPVS (OR = 0.714), and frontal cortex volume (OR = 0.959) compared to NDR. Further, the CSVD model showed a larger AUC (0.823, 95% CI: 0.781–0.866) than the brain atrophy model (AUC = 0.757, 95% CI: 0.706–0.808).ConclusionMicrovascular and neurodegeneration are significantly associated with DR. CSVD is a better imaging biomarker for DR than brain atrophy.
Evaluation of Telocytes in the Ovary, Oviduct and Uterus of Kyrgyz Mares According to Pregnancy Status
Authors: Risvanli Ali , Hatipoglu Fatih , Salykov Ruslan , Timurkaan Necati , Kadiralieva Nariste , Kasymalieva Kaliyman K. , Seker Ibrahim , Ekinci Elif 
Published: February 2025

ABSTRACTIn the current study, we aimed to determine the distribution of telocytes in the ovary, oviduct and uterus of Kyrgyz mares depending on whether they were pregnant. We also studied the progression during the first 6 months of pregnancy. To this end, ovary, oviduct and uterus tissues from 53 Kyrgyz mares were obtained post‐mortem. The mare tissue samples were divided into two groups: pregnant (n = 43) and non‐pregnant (n = 10). Telocyte levels in the tissues were determined using light microscopic and immunohistochemical methods. Subsequently, the data acquired were evaluated based on whether the mare was pregnant, and if so, the month of pregnancy was also taken into account. After the study, we found a higher number of telocytes in the myometrium (5.69 ± 0.90, p < 0.001) and oviduct propria (0.14 ± 0.05, p < 0.006) of pregnant mares. We also noted an increased number of telocytes in the oviduct propria (0.04 ± 0.02, p < 0.03) of mares 4 months into the pregnancy, and in the muscle layer (1.62 ± 0.57, p < 0.01), myometrium (4.83 ± 0.78, p < 0.03) and ovarian stroma (0.14 ± 0.06, p < 0.04) of mares 6 months into pregnancy. In conclusion, we observed an increase in telocytes in the ovaries, oviducts and uterus of Kyrgyz mares during pregnancy, with this increase becoming more marked towards the sixth month of gestation. Therefore, additional research on the role of telocytes in pregnancy may prove beneficial.
Case series: Symptom‐inhibited fentanyl induction (SIFI) onto treatment‐dose opioid agonist therapy in a community setting
Authors: Azar Pouya , Kim Jane J. , Davison Ruth , Barazanci Zoran , Ignaszewski Martha J. , Wong James S. H. , Machado Jessica , Harris Marianne , Krausz Michael , Mathew Nickie , Herring Andrew , Montaner Julio S. G. 
Published: February 2025

AbstractBackground and ObjectivesExisting opioid agonist therapy (OAT) guidelines are far from sufficient to address rising opioid tolerances and potency of the unregulated opioid market in North America. Inadequate starting doses of OAT are a universally recognized barrier for people who use fentanyl. Our objectives are to present a novel induction protocol called symptom‐inhibiting fentanyl induction (SIFI) that uses rapid intravenous fentanyl administration to inhibit symptoms of opioid withdrawal.MethodsWe describe two cases highlighting the potential clinical utility of SIFI.ResultsThis case series demonstrates two safe and successful transitions onto higher‐than‐standard doses of methadone and slow‐release oral morphine harnessing an emerging approach of SIFI in a community clinic setting.Discussion and ConclusionsThese results support emerging evidence that SIFI is safe and feasible to meet patients' opioid requirements and facilitate rotation onto OAT. Further studies are needed to increase the generalizability of these findings.Scientific SignificanceSafe transitions onto treatment‐dose OAT are of heightened clinical importance at a time when fentanyl and high‐potency synthetic opioids are now the norm. SIFI is a novel induction method that could address significant gaps in the currently available OAT options in the fentanyl era.
Aging Is Associated With Decreased Lactobacillus and Increased Cervicovaginal Inflammation in Canadian Women
Authors: Dang Ha T. , Noel‐Romas Laura , Knodel Samantha , Birse Kenzie , Lamont Alana , Kratzer Kateryna , McQueen Peter , Perner Michelle , Ayele Hossaena , Berard Alicia R. , Schellenberg John J. , McCorrister Stuart , Westmacott Garrett , Sandberg Bonnie , Yu Adelicia , Burnett Margaret , Poliquin Vanessa , Burgener Adam D. , Farr Zuend Christina 
Published: February 2025

ABSTRACTProblemAging is characterized by a general dysregulation of systemic immune responses that increases susceptibility to infections and malignancies. Immune cells in the female genital tract (FGT) are regulated by sex hormones, but little is known about the impact of aging and menopause on immunology in the FGT.Method of StudyThis study conducted an age‐focused sub‐analysis of cervicovaginal samples collected from 47 women enrolled in the Vaginal Mucosal Systems study in Winnipeg, Canada. Paired cervicovaginal lavage and cervical cytobrush were collected and analyzed by Luminex cytokine array, mass spectrometry based metaproteomics, metabolomics, and high dimensional flow cytometry.ResultsThe median age of study participants was 38 (range 19–88), with 12 over the age of 50. Increasing age was significantly correlated with increased cervicovaginal inflammation, including inflammatory cytokine MIP‐1β (r = 0.335, p = 0.023), and activated T cells (CD4+HLA‐DR+ r = 0406, p = 0.009; CD8+HLA‐DR+ r = 0.399, p = 0.010; CD8+CD38+HLA‐DR+ r = 0.386, p = 0.013). Proteomic analysis of cervicovaginal mucus identified 925 human proteins, with 108 (11.7%) significantly correlated with age. Pathway analysis indicated biofunctions related to immune response, migration, and myeloid cell phagocytosis increased with age. Interestingly, neutrophil related pathways decreased with age, including G‐CSF (r = −0.396, p = 0.006) and reactive oxygen species (z‐score = −2.607, p = 2.31E‐4). Vaginal Lactobacillus crispatus, a species associated with mucosal health, significantly decreased with age (r = −0.340, p = 0.022), with participants over the age of 50 more likely to have non‐Lactobacillus dominant microbiomes compared to those under 40.ConclusionsTogether, our data suggests that there is an increase in cervicovaginal inflammation and a decrease in L. crispatus that occurs with aging.