bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gambaran Tingkat Pengetahuan Remaja Putri Usia 10-19 Tahun Tentang Personal Hygiene Saat Menstruasi Di Rt 15 Sumberejo Kemiling Bandar Lampung
Authors: Dimas Ning Pangesti  , Praty Milindasari  
Published: January 2022

Pengetahuan merupakan hasil tahu dan ini terjadi setelah orang melakukan penginderaan terhadap suatu objek tertentu. Menstruasi adalah proses alamiah yang terjadi pada perempuan. Menstruasi merupakan perdarahan teratur dari uterus sebagai tanda bahwa organ kandungan telah berfungsi matang. Kebersihan perorangan adalah suatu tindakan yang dilakukan untuk memelihara kebersihan dan kesehatan seseorang untuk kesejahteraan fisik dan psikis. Mengidentifikasi tingkat pengetahuan remaja putri usia 10-19 tahun tentang personal hygiene saat menstruasi. Desain penelitian yang digunakan adalah deskriptif. Responden yang digunakan pada peneitian ini sebanyak 30 responden. Sampling yang digunakan yaitu accidentalsampling,. Hasil penelitian yang dilakukan pada 30 responden menunjukkan tingkat pengetahuan remaja usia 10-19 tahun tentang personal hygiene di RT 15 didapatkan hasil tingkat pengetahuan baik pada remaja sebanyak 12 (40% ) responden, tingkat pengetahuan cukup sebanyak 15 (50%) responden, dan tingkat pengetahuan kurang sebanyak 3 (10%) responden. Rata-rata tingkat pengetahuan baik pada remaja sebanyak 12 (40% ) yaitu dari pendidikan SMA, tingkat pengetahuan cukup sebanyak 15 (50%) yaitu pendidikan SMA 3 responden, SMP sejumlah 7 responden dan SD sejumlah 5 responden. Tingkat pengetahuan kurang sejumlah 3 (10%) pendidikan SD. Kesimpulan dari karakteristik responden berdasarkan usia 10-19 tahun, rata-rata responden yaitu berusia 14-19 tahun sejumlah 22 (73%). Rata-rata pendidikan responden yaitu SMA 15%. Rata-rata pekerjaan orang tua responden yaitu wiraswasta sejumah 15 (50%). Saran dalam penelitian ini adalah Meningkatkan tingkat pengetahuan remaja tentang personal hygiene saat menstruasi, perlu dilakukan pembinaan kepada penduduk desa secara terus menerus, melalui penyuluhan oleh petugas kesehatan dengan cara penjelasan yang berisi pesan tentang personal hygiene saat menstruasi
Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Authors: Chicón‐Bosch Mariona , Sánchez‐Serra Sara , Rosàs‐Lapeña Marta , Costa‐Fraga Nicolás , Besalú‐Velázquez Judit , Illa‐Bernadí Janet , Mateo‐Lozano Silvia , Cidre‐Aranaz Florencia , Grünewald Thomas G.P. , Díaz‐Lagares Ángel , Lopez‐Alemany Roser , Tirado Òscar M. 
Published: January 2025

Ewing sarcoma (EWS) is the second most common bone tumor affecting children and young adults, with dismal outcomes for patients with metastasis at diagnosis. Mechanisms leading to metastasis remain poorly understood. To deepen our knowledge on EWS progression, we have profiled tumors and metastases from a spontaneous metastasis mouse model using a multi‐omics approach. Combining transcriptomics, proteomics, and methylomics analyses, we identified signaling cascades and candidate genes enriched in metastases that could be modulating aggressiveness in EWS. Phenotypical validation of two of these candidates, cyclic AMP‐responsive element‐binding protein 1 (CREB1) and lipoxygenase homology domain‐containing protein 1 (LOXHD1), showed an association with migration and clonogenic abilities. Moreover, previously described CREB1 downstream targets were present amongst the metastatic‐enriched results. Combining the different omics datasets, we identified FYVE, RhoGEF, and PH domain‐containing protein 4 (FGD4) as a CREB1 target interconnecting the different EWS biological layers (RNA, protein and methylation status) and whose high expression is associated with worse clinical outcome. Further studies will provide insight into EWS metastasis mechanisms and ultimately improve survival rates for EWS patients.
Evidence of Relativistic Field‐Derivative Torque in Nonlinear THz Response of Magnetization Dynamics
Authors: Dutta Arpita , Tzschaschel Christian , Priyadarshi Debankit , Mikuni Kouki , Satoh Takuya , Mondal Ritwik , Pal Shovon 
Published: January 2025

AbstractUnderstanding the complete light‐spin interactions in magnetic systems is the key to manipulating the magnetization using optical means at ultrafast timescales. The selective addressing of spins by THz electromagnetic fields via Zeeman torque is one of the most successful ultrafast means of controlling magnetic excitations. Here it is showed that this traditional Zeeman torque on the spins is not sufficient, rather an additional relativistic field‐derivative torque is essential to realize the observed magnetization dynamics. This is accomplished by exploring the ultrafast nonlinear magnetization dynamics of rare‐earth, Bi‐doped iron garnet when excited by two co‐propagating THz pulses. First, by exciting the sample with an intense THz pulse and probing the magnetization dynamics using magneto‐optical Faraday effect, the collective exchange resonance mode is found between rare‐earth and transition metal sublattices at 0.48 THz. Further, the magnetization dynamics are explored via the THz time‐domain spectroscopic means. It is found that the observed nonlinear trace of the magnetic response cannot be mapped to the magnetization precession induced by the Zeeman torque, while the Zeeman torque supplemented by an additional field‐derivative torque follows the experimental evidences. This breakthrough enhances the comprehension of ultra‐relativistic effects and paves the way toward novel technologies harnessing light‐induced control over magnetic systems.
Asymmetric S Heteroatom Coordinated Dual‐Atom Catalysts and Coupled Anodic Sulfion Oxidation to Boost Electrocatalysis Oxygen Reduction
Authors: Wang Jun , Liu Xiaomei , Ma Chengbo , Duan Xiaoguang , Li Shuai , Li Ning , Liu Wen , Li Yang , Fan Xiaobin , Peng Wenchao 
Published: January 2025

AbstractConsidering the exceptional electronic regulation capability, p‐block elements can be used to regulate the charge density of traditional transition metal catalysts. In this work, CoGa‐NS‐C dual‐atom catalysts (DACs) are successfully synthesized through co‐precipitation and post‐annealing treatment. The atomic dispersion of Co and Ga and the synergistic coordination structure of CoN3S1 and GaN4 are confirmed by AC‐TEM, EXAFS, and XPS. Due to the steric hindrance effect of adsorbed *OH on the Ga site and the asymmetric S heteroatom coordination on Co species, the adsorption energy of *OOH intermediation on neighboring Co is thus enhanced greatly, resulting in the enhancement of the 2e‐ORR pathway. Besides, *OOH and Co─OH intermediates are detected by in situ FT‐IR and EC‐SHINERS spectroscopy. A high H2O2 selectivity of 90.3% and a fast H2O2 production rate of 1.12 mol h−1 g−1 can be reached. In addition, the cathodic oxygen reduction is used to couple with sulfion oxidation reaction (SOR) instead of the energy‐intensive OER reaction. In this coupling system, the SOR potential is 1.31 V lower than the OER process at the current intensity of 100 mA. Both the proposed dual‐atom DACs regulation strategy by p‐block elements and the ORR‐SOR coupling system are beneficial for achieving efficient and energy‐effective 2e‐ORR.
Constructing Robust and Efficient Ceramic Cells Air Electrodes Through Collaborative Optimization Bulk and Surface Phases
Authors: Zhang Ying , Wang Yibei , Liu Zhilin , Wang Zhen , Wang Yaowen , Xiao Youcheng , Niu Bingbing , Wang Xiyang , Wang Wenquan , He Tianmin 
Published: January 2025

AbstractSlow reaction kinetics of air electrodes is a common problem faced by low‐temperature (<650 °C) oxygen‐ion conducting solid oxide fuel cells (O‐SOFCs) and proton‐conducting reversible proton ceramic cells (R‐PCCs). Here, an innovative approach is proposed to design and prepare two efficient and durable Ba0.5Sr0.5Co0.8Fe0.2O3−δ (BSCF)‐based nanocomposites through self‐reconstruction strategy, which aim to optimize both the bulk and surface properties of electrode materials simultaneously. Specifically, the two nanocomposites with a nominal composition of Ba0.4Sr0.5Cs0.1Co0.7Fe0.2M0.1O3−δ (M═Ni, Zr) consisted of the major perovskite phase and surface‐enriched NiO and BaZrO3 minor phases. When Ba0.4Sr0.5Cs0.1Co0.7Fe0.2Ni0.1O3−δ (BSCsCFNi) is used as an air electrode in O‐SOFCs, the peak power density is 1.36 W cm−2 at 650 °C; while Ba0.4Sr0.5Cs0.1Co0.7Fe0.2Zr0.1O3−δ (BSCsCFZr) is used in R‐PCCs, a peak power density of 1.24 W cm−2 and a current density of −1.98 A cm−2 (1.3 V) are achieved at 650 °C, and exhibits stable reversibility over 100 h. Theoretical calculations and experiments indicate that Cs+ doping enhances the bulk conduction of oxygen ions and protons; NiO nanoparticles enhance oxygen adsorption and surface exchange; BaZrO3 nanoparticles increase steam adsorption and hydration capacity. This study provides a new idea for designing efficient and durable air electrodes of ceramic cells.
A Flexible Photovoltaic Fatigue Factor for Quantification of Mechanical Device Performance
Authors: Sun Lulu , Fukuda Kenjiro , Guo Ruiqi , Castriotta Luigi A. , Forberich Karen , Zhou Yinhua , Someya Takao , Brabec Christoph J. , Almora Osbel 
Published: January 2025

AbstractFlexible emerging photovoltaic technologies, such as organic and perovskite photovoltaics, hold great potential for integration into tents, wearable electronics, and other portable applications. Recently, Fukuda et al. (2024) propose a bending test protocol for standardizing the mechanical performance characterization of flexible solar cells, focusing on 1% strain over 1 000 bending cycles. This marked an important step toward establishing consistency and good practices in the literature. However, even with this unified protocol, accurately comparing the mechanical flexibility of solar cells is hindered by the variated influence of parameters like thickness, bending radius, and power conversion efficiency (PCE) evolution during mechanical testing. Herein, a new figure of merit is introduced, the flexible photovoltaic fatigue factor (F), which integrates PCE retention, strain, and bending cycles into a cohesive framework. Guided by a detailed multilayer mechanical model, this metric enables more accurate strain analysis and promotes consistent reporting, paving the way for performance optimization in flexible photovoltaics.
The Printed Path to Healing: Advancing Wound Dressings through Additive Manufacturing
Authors: Galvão Duarte Joana , Piedade Ana Paula , Sarmento Bruno , Mascarenhas‐Melo Filipa 
Published: January 2025

AbstractWound care challenges healthcare systems worldwide as traditional dressings often fall short in addressing the diverse and complex nature of wound healing. Given conventional treatments limitations, innovative alternatives are urgent. Additive manufacturing (AM) has emerged as a distinct and transformative approach for developing advanced wound dressings, offering unprecedented functionality and customization. Besides exploring the AM processes state‐of‐the‐art, this review comprehensively examines the application of AM to produce cellular‐compatible and bioactive, therapeutic agent delivery, patient‐centric, and responsive dressings. This review distinguishes itself from the published literature by covering a variety of wound types and by summarizing important data, including used materials, process/technology, printing parameters, and findings from in vitro, ex vivo, and in vivo studies. The prospects of AM in enhancing wound healing outcomes are also analyzed in a translational and cost‐effective manner.
Dynamically Assembling Magnetic Nanochains as New Generation of Swarm‐Type Magneto‐Mechanical Nanorobots Affecting Biofilm Integrity
Authors: Kralj Slavko , Da Silva Charlotte , Nemec Sebastjan , Caf Maja , Fourquaux Isabelle , Rols Marie‐Pierre , Golzio Muriel , Mertelj Alenka , Kolosnjaj‐Tabi Jelena 
Published: January 2025

AbstractBacterial resistance is gaining ground and novel, unconventional strategies are required to improve antibiotic treatments. As a synthetic analog of planktonic bacilli, the natural bacterial swimmers that can penetrate bacterial biofilms, ultra‐short propelling magnetic nanochains are presented as bioinspired magnetic nanorobots, enhancing the antibiotic treatment in biofilm‐forming Staphylococcus epidermidis. Propelling nanochains, activated by a low intensity (<20 mT) and low frequency (<10 Hz) rotating magnetic field (RMF), prompt the otherwise resistant biofilm‐forming bacteria to become sensitive to methicillin, resulting in the killing of 99.99% of bacteria. While magnetic force‐driven spherical magnetic nanoparticles were previously reported as unidirectional biofilm channel diggers, propelling nanochains emerge as second‐generation magnetic nanorobots, which, due to their magnetic core, shape anisotropy, and negative zeta potential, combine magnetic responsiveness, torque‐driven movement, and attractive electrostatic interactions to attach to bacterial aggregates and multi‐directionally protrude throughout the biofilm, indulging mechanical forces. These synergistic effects, in combination with an antibiotic drug, destroy the bacterial extracellular matrix and eradicate the formed biofilm, as confirmed with several complementary techniques.
Regulating Supramolecular Assembly and Disassembly of Chitosan toward Efficiently Antibacterial Lubricous and Biodegradable Hydrogel Urinary Catheters
Authors: Guo Yicheng , He Qitong , Al‐Handawi Marieh B. , Chen Tao , Naumov Panče , Zhang Lidong 
Published: January 2025

AbstractUrinary catheters serve as critical medical devices in clinical practice. However, the currently used urinary catheters lack efficient antibacterial and lubricating properties, often leading to discomfort with patients and even severe urinary infections. Herein, a new strategy of supramolecular assembly and disassembly of chitosan (Cs) is developed that enables efficient antibacterial lubricous and biodegradable hydrogel urinary catheters. Sodium lauryl sulfonate (SLS) is employed to induce supramolecular assembly on the surface of Cs film strips in an aqueous solution, resulting in the formation of hollow hydrogel catheters of Cs@SLS. Subsequent disassembly in a strong alkaline solution eliminates the SLS component, yielding neat Cs hydrogel catheters. The mechanical strength of these catheters reaches 16 MPa, exceeding that of similar devices made of plastics. The Cs hydrogel catheters are endowed with high antibacterial activity, capable of inhibiting the growth of Staphylococcus aureus (S. aureus), Escherichia coli (E. coli) and Proteus mirabilis(P. mirabilis) on its surface, while these bacteria are found to proliferate rapidly on plastic catheters within 24 h. They also demonstrate excellent lubricity, with a friction coefficient approaching zero, and thus about 13 times lower than that of plastic catheters. In vivo tests further confirm the biodegradability of the catheters, highlighting their strong potential for clinical applications.
Responsive Degradable Bottlebrush Polymers Enable Drugs With Superior Efficacy and Minimal Systemic Toxicity
Authors: Shao Liming , Zhang Hongrui , Sun Lei , Ning Lubin , Sun Xiuying , Qin Chaoke , Xu Wenhua , Xu Rui , Jia Fei 
Published: January 2025

AbstractBottlebrush polymers (BBPs) have garnered significant attention as advanced drug delivery systems, capable of transporting a diverse range of therapeutic agents, including both chemical drugs and biologics. Despite their effectiveness, the empty BBP vectors post‐drug release may pose long‐term safety risks due to their difficult systemic clearance. Here, a responsive degradable BBP platform for cancer therapy is developed, featuring a poly(disulfide) backbone grafted with fluorine‐terminated zwitterionic side chains. Anti‐cancer drugs are tethered to the backbone via a clinically approved valine‐citrulline (VC) linker. This design leverages the tumor's reductive environment and Cathepsin B overexpression for BBP rapid degradation and precise drug release restricted within tumor cells, thereby addressing systemic safety concerns over synthetic BBP and expanding the therapeutic window of anti‐cancer drugs simultaneously. Surface fluorination of BBP further enhances tumor accumulation and deep penetration. In vivo studies with monomethyl auristatin E (MMAE)‐loaded BBP in tumor‐bearing mice demonstrate substantial tumor suppression with minimal side effects. Together, these findings highlight the potential of responsive degradable BBP as a versatile unimolecular platform for cancer drug delivery, addressing existing challenges associated with synthetic BBP nanomedicines.
Transformation‐Invariant Laplacian Metadevices Robust to Environmental Variation
Authors: Huang Yao , Zhang Jingjing , Yang Qianru , Meng Lingsheng , Yang Tianzhi , Qiu Cheng‐Wei , Luo Yu 
Published: January 2025

AbstractAs one of the typical applications of metamaterials, the invisibility cloak has raised vast research interests. After many years’ research efforts, the invisibility cloak has extended its applicability from optics and acoustics to electrostatics and thermal diffusion. One scientific challenge that has significantly restricted the practical application of the invisibility cloak is the strong background dependence, that is, all passive cloaking devices realized thus far are unable to resist variation in the background refractive index. To tackle such a challenge, the concept of transformation‐invariant metamaterials (TIMs) is applied to static‐field systems and shows that, for any physical fields governed by Laplace equation, judiciously designed TIMs can be used to realize invisibility cloaks robust to the environment variation. As an experimental proof, an ideal direct current (DC) cloak‐is implemented based on TIMs and near‐field measurement results demonstrate that such a cloak can successfully conceal a large‐scale object when the background conductivity varies from 22 to 859 kS m−1. Moreover, the background‐immune cloaking effect is observed under arbitrary electric sources. The approach proposed in this work can be also applied to static magnetics, thermal diffusion, and beyond, enabling robust isolation of the target from the external field in versatile application scenarios.
Designing Current Collectors to Stabilize Li Metal Anodes
Authors: Hao Zhimeng , Lu Yong , Yang Gaojing , Zhao Qi , Yan Zhenhua , Chen Jun 
Published: January 2025

AbstractRechargeable batteries employing Li metal anodes have gained increasing attention due to their high energy density. Nevertheless, low stability and reversibility of Li metal anodes severely impeded their practical applications. Designing current collectors (CCs) with reasonable structure and composition is an efficient approach to stabilizing the Li metal anodes. However, an in‐depth comprehensive understanding about the design principles and modification strategies of CCs for realizing stable Li metal anodes is still lacking. Herein, a critical review focusing on the rational design of CCs for Li metal anodes is summarized. First, the requirements for CCs in Li metal anodes are elucidated to clarify the design objectives of CCs. Then, the modification strategies of CCs including lithiophilic site modification, 3D architecture construction, protective layer modification, and crystalline plane engineering, as well as the corresponding principles are highlighted. On this basis, the recent progress in the development of CCs for Li metal anodes is discussed. Finally, future directions are suggested to focus on developing operando monitoring technology, and designing the CCs and cells under practical conditions close to the requirements of commercial applications. This review will spur more insightful researches toward advanced CCs, and promote their commercialization.
Passive Isothermal Flexible Sensor Enabled by Smart Thermal‐Regulating Aerogels
Authors: Zhong Shenjie , Lu Bohan , Wang Duan‐Chao , Arianpour Brian , Wang Shaolei , Han Haiyu , Yin Junyi , Bao Hong , Liu Yina , Wen Zhen , Zhou Yunlei 
Published: January 2025

AbstractEnvironmentally induced sensor temperature fluctuations can distort the outputs of a sensor, reducing their stability during long‐term health monitoring. Here, a passive isothermal flexible sensor is proposed by using hierarchical cellulose aerogel (HCA) as the top tribonegative layer, which allows the sensor to adapt dynamic thermal environments through both radiative cooling and heat insulation. The radiative cooling effect can cool down the temperatures of a sensor in summer, while the hollow microfibers in HCA provide ultralow thermal conductivity to reduce internal heat loss in winter. The prepared passive isothermal sensor is capable of maintaining the rated working temperature over an extensive temperature range of 0−100 °C, demonstrating for gripping hot and cold objects. While monitoring human movements under direct sunlight, the temperature of a conventional sensor rose by 12.3 °C, whereas the sensor experienced an increase of only 0.3 °C. Therefore, this work presents a promising strategy for adapting to environments, enabling wearable electronics to function effectively in dynamic thermal conditions.
Ultrafast Lithium‐Ion Transport Engineered by Nanoconfinement Effect
Authors: Yang Yahan , Li Zefeng , Yang Zhilin , Zhang Qiannan , Chen Qian , Jiao Yuying , Wang Zixuan , Zhang Xiaokun , Zhai Pengbo , Sun Zhimei , Xiang Yong , Gong Yongji 
Published: January 2025

AbstractAmid the burgeoning demand for electrochemical energy storage and neuromorphic computing, fast ion transport behavior has attracted widespread attention at both fundamental and practical levels. Here, based on the nanoconfined channel of graphene oxide laminar membranes (GOLMs), the lithium ionic conductivity typically exceeding 102 mS cm−1 is realized, one to three orders of magnitude higher than traditional liquid or solid lithium‐ion electrolyte. Specifically, the nanoconfined lithium hexafluorophosphate (LiPF6)‐ethylene carbonate (EC)/ dimethyl carbonate (DMC) electrolyte demonstrates the ionic conductivity of 170 mS cm−1, outperforming the bulk counterpart by ≈16 fold. At the ultralow temperature of −60 °C, the nanoconfined electrolyte also maintains a practically useful conductivity of 11 mS cm−1. Furthermore, the in situ experimental and theoretical framework enables to attribute the enhanced ionic conductivity to the layer‐by‐layer cations and anions distribution induced by high surface charge and nanoconfinement effects in GO nanochannels. More importantly, integrating such rapid lithium‐ion transport nanochannel into the LiFePO4 (LFP) cathode significantly improves the high‐rate and long‐cycle performance of lithium batteries. These results exhibit the convention‐breaking ionic conductivity of nanoconfined electrolytes, inspiring the development of ultrafast ion diffusion pathways based on 2D nanoconfined channels for efficient energy storage applications.