bluuebunny/crossref_metadata_2025_split huggingface dataset:
Staphylococcal toxic shock syndrome because of skin infection – a case report
Authors: Gupta Ajay K. , Jain Nishesh , Jindal Saurabh , Puri Saurabh , Randhawa Gulshan S. 
Published: September 2022

Abstract
Staphylococcal toxic shock syndrome (STSS) is a toxin-mediated disease. It is a severe fatal disease inducing immune-mediated inflammatory reaction and occurs because of exotoxin produced by Staphylococcus aureus. Common signs and symptoms at the time of presentation lead to misdiagnosis and delay in initiation of treatment. Prognosis depends primarily on early diagnosis and prompt treatment. This is a case of a young adult male presented with fever, rash, and hypotension and diagnosed with STSS.
Role and importance of journal reader: Scientific contribution of letter to editor
Authors: Kumar Raman 
Published: September 2022

Abstract
Letters to the editor are not often considered high in the publication hierarchy but they contribute immensely to the growth and development of any discipline and scientific examination. In many academic settings, letters to editors are not accounted for promotion and career advancement. However, letter to editor publications by active readers are no lesser contribution to science and they should be considered of equal stature and at par with other published manuscript types.
The yield of fecal occult blood testing as a screening tool for colon cancer in a primary care setting
Authors: Almoneef Naif M. , Alkhenizan Abdullah H. , Mahmoud Ahmed S. , Alsoghayer Suad A. , Aldheshe Abdulaziz A. 
Published: September 2022

Background/Aims:
The most common cancer among men and the third most common among women in Saudi Arabia is colon cancer. This study aimed to evaluate the yield of the fecal occult blood test (FOBT) used as a screening tool for colon cancer.

Settings and Design:
Medical records of all patients above the age of 50 years who had visited the Family Medicine clinic at King Faisal Specialist Hospital and Research Centre in Riyadh, Saudi Arabia and who had undergone the FOBT screening between January 2002 and March 2017 were retrospectively reviewed.

Materials and Methods:
We collected patients’ demographic data, FOBT results, and colonoscopy pathology reports results.

Statistical Analysis:
Data were analyzed using the Statistical Package for Social Science Version 25 (IBM Corp., Armonk, NY, USA).

Results:
We included 2179 patients in this study. The mean age was 59.8 ± 8 years. As a result of the FOBT screening, 19.7% of the patients had a positive FOBT. Colon cancer accounted for 3.5% of all abnormal colonoscopy pathology reports. The Saudi age-standardized incidence rate (ASIR) in our study was 26.56 per 100,000 persons.

Conclusion:
FOBT is a feasible tool that can be used for colon cancer screening in primary care settings. The Saudi ASIR in our study was higher than the Saudi Cancer Registry, but it was still lower in comparison to other countries. We recommend the establishment of a national community-based colon cancer screening program.
A follow-up study of surgically managed benign vocal cord lesions using vocal handicap index – 10 score
Authors: Singh Deepali , Baruah Binayak , Basu Debaditya , Kumar Alok , Gupta Ajay 
Published: September 2022

Background and Objectives:
Benign lesions of the vocal cords not only impair the patient’s ability to communicate due to poor pronunciation and voice capabilities, but they also cause a variety of psychological and social problems, worsening their quality of life. To assess voice handicap, Voice Handicap Index (VHI)-10 is an easy-to-administer, valid and reliable tool. The present study was conducted to compare the pre-operative and post-operative well-being of patients with benign vocal cord lesions using VHI-10 among patients attending our Outpatient department.

Materials and Methods:
The study was a hospital based observational study with prospective study design, conducted over a period of 17 months (August 2019 to December 2020) on 53 patients who were clinically diagnosed to have benign vocal cord lesion and underwent micro laryngeal surgery followed by histopathological confirmation. Follow-up of the participants was done on 4th and 8th week post-operatively. Visualization of the condition of the laryngeal structures using laryngoscope assessment of VHI-10 score was done at each follow-up visit.

Results:
In our study, out of 53 study participants, approximately one-third of the cases were seen in the 5th decade, that is, 40-49 years. The mean (±SD) age of the study participants was 43.2 (±12.1) years. There was male predominance (73.6%) with male to female ratio of 2.78:1. Majority of the patients had voice-demanding profession with history of vocal abuse. In cases of non-professional voice users, the highest incidence was noted in homemakers (11.4%). Smoking was noted in nine male patients while all the female patients were non-smokers. Habit of alcohol consumption was seen in 15.1% patients and 7.5% patients had habit of other substance abuse such as tobacco chewing, betel nut chewing, etc. Vocal polyps were the most common benign lesions found in 43.3% of the patients. Preoperatively mean (± SD) VHI-10 score was 20.7 (±3.5) which significantly decreased to 12.6 (±2.5) at 4th week post-operatively and 8.5 (±2.3) at 8th week post-operatively. Mean differences between pre-operative and post-operative scores were statistically significant (P < 0.01), depicting that there was improvement in the voice of the patients post-operatively.

Conclusion:
The VHI-10 scale is shown to be a good and convenient tool for assessing patient voice handicap and determining improvement post-operatively. Wider studies with larger sample size in different parts of the country may be recommended to validate the findings of the study. In addition to surgical excision of lesion, speech therapy, and patient counselling are indubitably essential measures that should be undertaken for each patient so as to alleviate the handicapping effect of voice disorder and improve the overall quality of life of the individuals.
Comparison of modified McIndoe and Davydov vaginoplasty in patients with MRKH syndrome in terms of anatomical results, sexual performance and satisfaction
Authors: Deldar-Pesikhani Maryam , Ghanbari Zinat , Shahrbabaki Fareideh Sabzi , Nassiri Saina , Raznahan Maedeh , Shokrpour Maryam 
Published: September 2022

Introduction:
To compare the modified McIndoe versus Davydov vaginoplasty techniques in terms of anatomical results, sexual performance, and satisfaction.

Methods:
From September 2019 to June 2021, a comparative study was conducted on 20 patients with MRKH syndrome who underwent either McIndoe vaginoplasty (McIndoe group, 10 cases) or Davydov vaginoplasty (Davydov group, 10 cases) in a university-based tertiary care hospital (Imam Khomeini Hospital) in terms of anatomical results, sexual performance, and satisfaction. Functional results were assessed using the Female Sexual Function Index (FSFI).

Results:
All surgical procedures (n = 20) were performed successfully. Patients in the modified McIndoe group were similar to those in the Davydov group in terms of hospital stay and intraoperative complications. However, postoperative complications were higher in the McIndoe group. There were no significant differences in the neovaginal length and width of the two groups at the 6-month follow-up (P > 0.05). Other parameters (duration of mold use and blood transfusion) were similar for all patients in the two groups. At 12 months after surgery, all patients had regular sexual activity. No significant differences were found in either group.

Conclusions:
In terms of anatomical results, sexual performance, and satisfaction, the two techniques were similar.
Anxiety and depression among new cancer patients
Authors: Safaie Nilufar , Zeinali Hadi , Ghahramanfard Farahnaz , Mirmohammadkhani Majid , Moonesan Mohammadreza 
Published: September 2022

Introduction and Objective:
Definitive diagnosis, tedious treatment methods, and long treatment duration are possible factors contributing to psychiatric disorders in cancerous patients, including anxiety and depression. Accordingly, this study aimed to investigate the effective factors on the occurrence of psychiatric disorders in newly diagnosed cancer patients.

Methods:
This descriptive-analytical study was conducted in Semnan, Iran, in 2018, in which 122 patients with cancer were included. In this study, the Hospital Anxiety and Depression Scale questionnaire was used to collect the required data. Frequency comparisons between the sub-groups were performed using the Chi-square test and, if necessary, Fisher’s exact test. Moreover, the T-test or Mann–Whitney U test was used to compare numerical variables.

Results:
In this study, the mean values of total depression and total anxiety among patients were 26.2% and 28.6%, respectively. According to the results, anxiety was observed in 74.3% of low-income people and 80% of females. Gender and income were significantly associated with anxiety in patients with cancer (p < 0/05). However, no significant association was found between depression and the variables of gender, age, level of education, and income (P > 0.05).

Conclusion:
The inclusion of psychiatric interventions in the treatment program of cancer patients can be effective in controlling psychiatric disorders, especially depression and anxiety.
Policy, programs, and activities for promotion of water, sanitation and hygiene practices in schools of India
Authors: Dakhode Sarika U. , Gaidhane Abhay M. , Choudhari Sonali G. 
Published: September 2022

Abstract
The data has been compiled from peer-reviewed journals, published books, some organizational reports, and papers from conferences. The major electronic databases that have been utilized for this review, to collect publications that are relevant to the research aims include Google Scholar, PubMed, and Science Direct databases. The keywords used to search were WASH, Hygiene, School, Policy, and Programs. In addition, primary explorations were also steered in the Johns Hopkins Health Resource and US CDC Library, and Ministry of Health and family welfare, India.
Ayurveda for management of migraine: A narrative review of clinical evidence
Authors: Soman Akhila , Venkatram Shivakumar , Chikkanna Umesh , Ramakrishna Kishore K. , Bhargav Hemanth , Mailankody Pooja , Varambally Shivarama 
Published: September 2022

Abstract
Migraine is a primary headache disorder characterized by recurrent attacks. The economic and societal burden of migraine is substantial, affecting patients’ quality of life in terms of work, social activities, and family life. This article attempts to review the available literature for clinical evidence of Ayurveda in the management of migraines. We performed a literature search from January 2000 to July 2020 on popular search engines such as Pub Med, Google Scholar, and AYUSH Research Portal using the keywords “Complementary and Alternative Medicine (CAM) and Migraine”, “Ayurveda and Migraine” and “Panchakarma and Migraine”. The selection criteria involved published clinical trials, including pilot studies, whereas review articles, concept papers, letters to the editor, and studies published in languages other than English were excluded. Out of 77 studies that were screened, 12 articles that satisfied the selection criteria consisted of six Randomized controlled Trials (RCTs), five non-RCTs, and one pilot study. Among them, ten studies used polyherbal and Herbo mineral formulations, two studies contained no oral medications, three trials utilized external therapies, and ten studies used panchakarma procedures. Eleven studies found Ayurveda to be clinically beneficial as monotherapy, while one study demonstrated the usefulness of Ayurveda as an add-on to conventional management. This review reveals the beneficial role of Ayurveda in the management of migraines without many side effects. Yet several limitations exist, like small sample size, short follow up, and lack of better outcome measures for pre and post-assessments. Future research should overcome these limitations and follow a robust methodology so that definitive conclusions can be drawn.
Funding opportunities for higher learning, medical and nursing research in India: An overview
Authors: Verma Ranjana , Phalswal Uma , Shafquat Nassema , George Jisa 
Published: September 2022

Abstract
Medical research is an important aspect of medical education and is required to maintain quality. Funding can assist a researcher in doing extensive research in a certain area by boosting study variables, sample size and use of sophisticated state-of-the-art equipments. India’s funding for health research is limited, and only a small percentage of that is used for public health research. Many health professionals have a lot of great ideas for health-related research but do not know where to start looking for financing. A review was created to help medical and nursing professionals to find the correct funding source for their research. There are many governments’ organisations in India, which provide funds for research, grants and higher learning research fellowships. We tried to give an overview of some organisations with their benefits. This review includes the Indian Council of Medical Research (ICMR), Defence Research and Development Organisation (DRDO), Science and Engineering Research Board (SERB), India Alliance, Department of Science and Technology (DST), Department of Biotechnology (DBT), Council of Scientific and Industrial Research (CSIR), Department of Health Research (DHR), Trained Nurses Association of India (TNAI), and the Nursing Research Society of India (NRSI). This review makes aware health professionals to the funding agency as well as the time of funding and fellowship application.
How Indian obese population managed their lifestyle during first and second lockdown during COVID-19 pandemic? - A comparative study
Authors: Jadon Ranveer Singh , Tripathi Divya , Payal  , Mittal Mansi , Pandey Mayank , Gupta Karishma , Allen Swati , Ray Animesh , Ranjan Piyush , Sethi Prayas , Vikram Naval K. 
Published: September 2022

Background:
People from all over the world have been affected by the COVID-19 (SARS-CoV-2) pandemic. The lockdown during the pandemic has impacted the lifestyle of most of the population. The aim of the present study is to compare the effect of COVID lockdown-1 and lockdown-2 on the lifestyle of the obese Indian population.

Methods:
This was a cross-sectional study conducted during the COVID-19 lockdown on obese adults. A well-structured questionnaire was developed and administered among the study population. The study was conducted in two phases (lockdown-1 and lockdown-2). A total of 390 subjects were included in the study (260 subjects in the lockdown-1 phase and 130 subjects in the lockdown-2 phase). Data on diet, sleep, stress, and physical activity were obtained and analyzed.

Results:
The mean age of the participants of phase-1 in the study was 41.7 ± 10.2 years and the participants of phase-2 were 44.5 ± 9.2 years. Statistically significant differences were observed between lockdown-1 and lockdown-2 in terms of monitoring of weight and other comorbid conditions, changes in the consumption of refined flour and processed foods, sugar and sugar-sweetened foods, oils and ghee, duration of physical activity, changes in the duration of sleep, and the stress levels related to COVID-19 (P < 0.001).

Conclusion:
The impact of the lockdowns on health was very significant and different areas of lifestyle were affected in both the lockdowns. Weight gain was reported in both phases of the lockdown. The monitoring of health parameters, eating frequency, diet, and stress levels were affected during lockdown-1, whereas during lockdown-2, sleep duration and physical activity were affected. A comprehensive lifestyle modification plan is required to be developed to avoid these effects in the future.
CoRe study: COVID-19 and remdesivir: An insight into the current health planning and policy
Authors: Samim MM , Dhar Debjyoti , Singh Vikram , B.S Nagaraja , M.S Shahyan , Dey Treshita , Parvin Naznin , Dutta Debayan , Shah Rutul D , M Bhavesh , Goyal Sheeetal , Kariyappa Mallesh , Saha Subhrakamal , Goswami Preetam , Das Debarup , Shah Shivani , KN Ramesh , Shekhar Jaipuriar 
Published: September 2022

Introduction:
The ongoing coronavirus disease-2019 (COVID-19) pandemic has witnessed rampant use of the repurposed drug, remdesivir, despite its conflicting evidence and rapidly changing guidelines.

Methods:
A cross-sectional, country-wide, questionnaire-based, electronic survey was conducted among the healthcare professionals involved in COVID-19 management from April 18 to May 18, 2021.

Results:
Out of 231 responses, 185 were included. Significantly, greater knowledge of trials was reported by the frontline healthcare professionals compared to those who are not involved in COVID-19 care. Medicine practitioners and pulmonologists expressed greater willingness to continue remdesivir (Odds ratio (OR) 5.329, 95% Confidence interval (CI) 2.31–12.291 and 5.063, 95% CI 1.414–18.129, respectively). The rationale attributed was personal experience, current guidelines, non-availability of any alternate antiviral drug, expert recommendations, and local hospital policy either alone (20%, 8.1%, 5.9%, 2.7%, and 2.2%, respectively) or in combination (46.5%, 39.5%, 29.2%, 21.1%, and 15.7%, respectively). Awareness of evidence and knowledge of landmark studies made no statistically significant impact on clinical decision-making. Improved clinical outcomes were reported by 10/22 (45.4%) practitioners who used remdesivir for unconventional indications.

Conclusion:
The study throws critical insights into the current perspectives of doctors on remdesivir in clinical management and its potential impact on current health planning strategies.
Morphological study of the menisci of the knee joint in human cadaver in Jharkhand population
Authors: Gupta Govind Kumar , Kumar Prashant , Rani Sudha , Kumari Anita 
Published: September 2022

Introduction:
Sports are the leading cause of joint injuries, particularly in the knees. Knee menisci are an important functional unit that aids in load distribution and hence reduces stress on the knee joint. Meniscal morphology provides information on exact size and shape, which is important for meniscal transplantation in cases of meniscal damage. The study’s goal is to determine the morphological variation in the shape of menisci, as well as the width and thickness of menisci.

Method:
This study was conducted at the Rajendra Institute of Medical Sciences (RIMS) Ranchi, Department of Anatomy. In this study, 100 menisci were taken from 50 adult cadaver knee joints available in the dissection hall.

Result:
Six morphological kinds of menisci were identified after a morphological and morphometric study of 100 menisci. The most common crescent-shaped menisci (96%) were found in 50 medial menisci (MM), while the most common C-shaped menisci were found in 50 lateral menisci (LM, 94%). There was no statistically significant difference in thickness between the anterior, middle, and posterior thirds of the MM in the morphometric analysis. The thickest section of the lateral meniscus (LM) was in the middle third. There was no significant variation in the width of the LM among the different thirds in the current study. The posterior portion of the medial meniscus (MM), on the other hand, was the widest.

Conclusion:
The findings of this study support meniscal anatomy in terms of surgical technique and arthroscopy of the knee joint, as well as contributing to a better understanding of meniscal architecture and meniscal transplantation. As a result, health workers who treat meniscal injuries should be aware of the probable anatomical differences.
Infodemics during era of COVID-19 pandemic: A review of literature
Authors: Sharma Lokesh D. , Joshi Krupal J. , Acharya Tejas A. , Dwivedi Manish G. , Sethy Ghanashyam B. 
Published: September 2022

Abstract
The coronavirus disease 2019 (COVID-19) pandemic, caused by the new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread across the globe and has affected the health of millions of people. During the pandemic, social media was the major source of information for isolated and anxious people. Infodemics is defined as “an overburden of information – some accurate and some not – that makes it hard for people to find trustworthy source and reliable guidance when they need it.” Misinformation raised out of infodemics during COVID-19 created many serious issues regarding the prevention and treatment of COVID-19. With the help of available literature, we aimed to review the role of infodemic in relation to worsening of COVID-19 spread and vaccine utilization with possible preventable measures to control infodemic. Various social media platforms were a major source of infodemic. The active role of world agencies, narrative guidelines by the local authority, use of artificial intelligence (AI) by social media platforms and active participation of community and health care professionals can control infodemics effectively.
Evaluation of hematological parameters in pulmonary tuberculosis patients
Authors: Shah Amar R. , Desai Killol N. , Maru Alpeshkumar M. 
Published: September 2022

Introduction:
Tuberculosis (TB) is the most common infectious disease caused by mycobacterium tuberculosis. Apart from the lungs, tuberculosis also affects the bone marrow. There are significant hematological abnormalities that occur in association with tuberculosis. So we can use these hematological parameters as a marker for the diagnosis, prognosis, and response to therapy.

Aims:
To evaluate the hematological parameters in pulmonary tuberculosis patients.

Methods and Materials:
A total of 70 diagnosed tuberculosis patients and 70 healthy controls were selected by purposive sampling in this study. About 4 ml of venous blood was collected with proper aseptic precaution. 2 ml ethylenediamine tetra acetic acid (EDTA) tube blood was used for hematological analysis by using Siemens Advia 2120i 5-part hematology analyzer. Rest 2 ml blood was used for measurement of erythrocyte sedimentation rate (ESR) by Wintrobe’s method.

Results:
The hemoglobin, packed cell volume (PCV), and blood indices values were significantly lower compared to healthy controls in both sexes. White blood cell (WBC) count, absolute neutrophil count, platelet count, and ESR values were significantly increased in tuberculosis patients as compared to healthy controls and were found to be statistically significant (P-value < 0.05).

Conclusions:
To measure hematological parameters in tuberculosis is a simple and cost-effective method to predict the course of the disease and monitor complications in developing countries like India.