bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH MODEL PEMBELAJARAN VISUAL AUDITORY KINESTETIC (VAK) TERHADAP PEMAHAMAN KONSEP SISWA
Authors: Khasanah Eka Kristanti Nur , Munawaroh Fatimatul , Qomaria Nur , Muharrami Laila Khamsatul 
Published: June 2022

Penelitian dilakukan untuk mengetahui pemahaman konsep siswa setelah menggunakan model pembelajaran VAK. Penelitian dilakukan di SMPN 1 Padangan dengan teknik pengambilan sampel menggunakan purposive sampling dengan kelas VIII E sebagai kelas kontrol dan kelas VIII F sebagai kelas eksperimen. Teknik pengumpulan data menggunakan angket, observasi dan dokumentasi. Hasil penelitian menunjukkan bahwa ada pengaruh model pembelajaran VAK terhadap pemahaman konsep mendapat nilai signifikansi 0,0000,05 dengan rumus –thitungttabelthitung (-14,0821,99914,082) H0 ditolak dan pemahaman konsep siswa setelah diterapkan model VAK rata-rata persentase kelas eksperimen sebesar 77,50% sedangkan kelas kontrol sebesar 55,22%.
ANALISIS KEMAMPUAN KOMUNIKASI SISWA DENGAN PERBANDINGAN MODEL SAVI DAN MODEL AIR
Authors: Sugiharto Aries , Hidayati Yunin , Hadi Wiwin Puspita , Ahied Mochammad 
Published: June 2022

Penelitian ini bertujuan untuk mengetahui perbedaan kemampuan komunikasi siswa dengan menggunakan model SAVI dan AIR. Penelitian ini menggunakan metode pre-experimental tipe the static group pretest-posttest design di SMPN 1 Baureno. Populasi adalah semua kelas VII. Teknik pengambilan sampel menggunakan purposive sampling. Sampel dalam penelitian ini adalah siswa kelas VIIC dan kelas VIID. Teknik pengumpulan data yang digunakan adalah tes dan observasi. Teknik analisis data menggunakan uji mann-whitney. Berdasarkan hasil penelitian diperoleh: (1) terdapat perbedaan kemampuan komunikasi tulisan yang menggunakan model SAVI dan model AIR dengan nilai signifikansi 0,0010,05, (2) Tidak ada perbedaan kemampuan komunikasi lisan yang menggunakan model SAVI dan model AIR dengan nilai signifikansi 0,471 0,05.
ANALISIS KETERAMPILAN BERPIKIR KRITIS SISWA MELALUI MODEL PEMBELAJARAN CHILDREN LEARNING IN SCIENCE (CLIS) DENGAN STRATEGI SCAFFOLDING
Authors: Fitriyah Nor , Munawaroh Fatimatul , Hadi Wiwin Puspita , Qomaria Nur 
Published: June 2022

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Children Learning In Science (CLIS) dengan startegi Scaffolding terhadap keterampilan berpikir kritis siswa. Penelitian menggunakan metode quasi eksperimental design dengan desain nonequivalent control design dan dilaksanakan di MTs. Miftahul Ulum Gayam dengan populasi semua kelas VIII pada pokok pembahasan getaran, gelombang, bunyi, sistem pendengaran manusia, dan sisem sonar. Teknik pengambilan sampel menggunakan teknik nonprobability sampling dengan desain purposive sampling. Teknis analisis data menggunakan uji t sampel bebas. Berdasarkan hasil penelitian ada pengaruh model pembelajaran CLIS dengan strategi Scaffolding terhadap keterampilan berpikir kritis siswa dengan signifikansi sebesar 0,000 menunjukkan nilai signifikansi kurang dari 0,05. Keterampilan berpikir kritis siswa kelas eksperimen lebih tinggi dari kelas kontrol, rata-rata posttest kelas eksperimen 72% dengan kategori tinggi dan kelas kontrol sebesar 67% dengan kategori tinggi. Keterlaksanaan pembelajaran sebesar 97% dengan kategori sangat tinggi. Respon siswa rata-rata pernyataan positif sangat setuju 23,53%, setuju 39,41%, tidak setuju 24,71%, dan sangat tidak setuju 12,35% sedangkan pernyataan negatif sangat setuju 8,82%, setuju 22,94%, tidak setuju 55,88%, dan sangat tidak setuju 12,35%.
PENGEMBANGAN MEDIA SCRAPBOOK BERBASIS PICTORIAL RIDDLE PADA MATERI PENCEMARAN LINGKUNGAN
Authors: A’yun Ulfi Qurrotu , Muharrami Laila Khamsatul , Qomaria Nur , Wulandari Ana Yuniasti Retno 
Published: June 2022

Penelitian ini bertujuan untuk mengetahui kelayakan media scrapbook berbasis pictorial riddle, keterbacaan, dan minat belajar siswa pada materi pencemaran lingkungan. Penelitian ini menggunakan model pengembangan ADDIE dan desain penelitian menggunakan desain One-Shot Case Study. Media yang dikembangkan diterapkan di kelas VII A SMP Negeri 2 Blega. Berdasarkan hasil pengembangan dan penelitian (R D) diperoleh data sebagai berikut: 1) Hasil rata-rata kelayakan media scrapbook sebesar 90,72% dengan kriteria sangat valid. 2) Hasil rata-rata keterbacaan media scrapbook sebesar 87,50% dengan kriteria sangat baik. 3) Hasil rata-rata minat belajar siswa sebesar 86,50% dengan kriteria sangat berminat.
Analisis Kurikulum Pendidikan Anak Usia Dini Bermuatan Kearifan Lokal Batik Madura
Authors: Yuniar Dias Putri , Tri Ariyanto Fajar Luqman , Rizqiyah Itmamatur 
Published: June 2022

Penelitian ini fokus pada pengembangan panduan kurikulum tingkat satuan pendidikan untuk PAUD yang diintegrasikan dengan muatan kearifan lokal Madura yaitu Batik Tanjung Bumi yang ada di Kabupaten Bangkalan. Salah satu batik di Madura yang terkenal adalah batik Tanjung Bumi Bangkalan, batiknya dibuat dengan menggunakan teknik khusus yang biasa dikenal batik gentongan. Proses penelitian pengembangan ini melibatkan kolaborasi dengan pendidik PAUD, dosen dan mahasiswa dalam tahapan kegiatan. Kurikulum Tingkat Satuan Pendidikan (KTSP) untuk PAUD adalah kurikulum operasional yang dikembangkan dan dilaksanakan sesuai dengan karakteristik satuan PAUD. Pengembangan panduan KTSP untuk PAUD ini dilakukan menggunakan rangkaian penelitian pengembangan dari Plomp yang ditempuh melalui empat tahapan. Tahapan penelitian ini yaitu tahap analisis, tahap desain, tahap mengkonstruk dan tahap evaluasi. Hasil produk penelitian berupa panduan kurikulum tingkat satuan pendidikan untuk PAUD bermuatan kearifan lokal batik Madura yang telah diuji validasi dari ahli media dan materi menunjukkan bahwa prototipe panduan layak untuk digunakan. Uji coba skala kecil yang menunjukkan bahwa panduan yang dikembangkan layak digunakan dengan prosentase 73%. Uji coba skala besar mendapatkan hasil sebersar 69% yang diartikan panuan dapat digunakan guru PAUD sebagai acuan dalam menciptkan kegiatan pembelajaran yang bernuanasa kearifan lokal Batik Tanjung Bumi Bangkalan.
Bidirectional DC-DC Converter Circuits and Smart Control Algorithms: A Review
Authors: V Viswanatha , A.C Ramachandra , R Venkata Siva Reddy 
Published: June 2022

Abstract
The entire article has been dedicated to cover the current state-of-the-art in Bidirectional DC-DC converter topologies and its smart control algorithms, identified the research gaps and concluded with the motivation for taking up the work. It covers the literature survey of Bidirectional buck-boost DC-DC converters and control schemes are carried out on two aspects, one is on topology perspective and another one is on control schemes. Different topologies with and without transformers of bidirectional DC - DC converters are discussed. Non-isolated converters establish the DC path between input and output sides while transformer based converters cancels the DC path in between input and output sides since it introduces AC line between two DC lines just like in flyback converter. Transformer less converter is preferred when there is no much protection needed for load from high voltage levels also these converters are used in high power applications. The Bidirectional DC-DC converter can switch the power between two DC sources and the load. To do so, it has to use proper control schemes and control algorithms. It can store the excess energy in batteries or in super capacitors. In contrast, isolated topologies contain transformers in their circuits. Due to this, it offers advantages like safeguarding sensitive loads from high power which is at input side. In addition to it, multiple input and output ports can be established. With the isolation in DC-DC converters, input and output sections are separated from electrical stand point of view. With isolation, both input and output sections will not be having common ground point .The DC path is removed with isolation due to usage of transformer in DC-DC converters. In contrast to its features, it is capable to be used in low power applications since transformer is switching at high frequency, the size of the coil reduces and hence it can handle limited rate of current. The bidirectional DC-DC converters are categorized based on isolation property so called isolated bidirectional converters. Features and applications of each topology is presented. Comparative analysis w.r.t research gaps between all the topologies is presented. Also the scope of control schemes with artificial intelligence is discussed. Pros and cons of each control scheme i.e. research gaps in control schemes and impact of control scheme for bidirectional DC-DC converters are also presented.
Problems and Countermeasures for Surgical Resection of Primary Pulmonary Artery Sarcoma
Authors: Ichinokawa Hideomi , Takamochi Kazuya , Fukui Mariko , Hattori Aritoshi , Matsunaga Takeshi , Suzuki Kenji 
Published: June 2022

Abstract
Background
This study clarified the problems and countermeasures of surgical treatment by examining surgical cases of pulmonary artery sarcoma.
Methods
The records of 10 patients with pulmonary artery sarcoma who underwent surgery at our hospital between January 2007 and October 2020 were retrospectively examined.
Results
The positive rate of vascular stumps was 7/10. Chest computed tomography scan showed positive margins of ≤ 20 mm between the tumor and surgical dissection in all cases (6/6). Additionally, the distance between the tumor location on computed tomography and the dissection line during surgery needed to be at least 20 mm (2/3). However, even at a distance of 25 mm, one case with a positive margin was observed. Postoperative recurrence was 6/9 cases, and the median recurrence period was as short as 9 months (range, 3-19 months). Postoperative treatment was required in 4/9 cases (chemotherapy/radiotherapy/chemoradiotherapy = 1/2/1). The median survival was 11 months (range, 0.5-24 months).
Conclusions
Extended surgery should be performed as much as possible, with a distance of at least 20 mm between the location of the tumor on computed tomography scan and the incision line during surgery. Intensive care for intrathoracic recurrence follow-up is required for 1 year after surgery.
Induction of iPSC-derived Prg4-positive cells with characteristics of superficial zone chondrocytes and fibroblast-like synovial cells
Authors: Satake Takashi , Komura Shingo , Aoki Hitomi , Hirakawa Akihiro , Imai Yuuki , Akiyama Haruhiko 
Published: June 2022

Abstract
Background: Lubricin, a proteoglycan encoded by the PRG4 gene, is synthesised by superficial zone (SFZ) chondrocytes and synovial cells. It reduces friction between joints and allows the smooth sliding of tendons. Although lubricin has been shown to be effective against osteoarthritis and synovitis in animals, its clinical application remains untested. In this study, we aimed to induce lubricin-expressing cells from pluripotent stem cells (iPSCs) and applied them locally via cell transplantation.Methods: To generate iPSCs, OCT3/4, SOX2, KLF4, and L-MYC were transduced into fibroblasts derived from Prg4-mRFP1 transgenic mice. We established a protocol for the differentiation of iPSC-derived Prg4-mRFP1-positive cells and characterised their mRNA expression profile. Finally, we injected Prg4-mRFP1-positive cells into the paratenon surrounding the Achilles tendons and knee joints of severe combined immunodeficiency mice and assessed lubricin expression.Results: Wnt3a, activin A, TGF-β1, and bFGF were applied to induce the differentiation of iPSC-derived Prg4-mRFP1-positive cells. Markers related to SFZ chondrocytes and fibroblast-like synovial cells (FLSs) were expressed during differentiation. RNA-sequencing indicated that iPSC-derived Prg4-mRFP1-positive cells manifested expression profiles typical of SFZ chondrocytes and FLSs. Transplanted iPSC-derived Prg4-mRFP1-positive cells survived around the Achilles tendons and in knee joints. Conclusions: The present study describes a protocol for the differentiation of iPSC-derived Prg4-positive cells with characteristics of SFZ chondrocytes and FLSs. Transplantation of lubricin-expressing cells offers promise as a therapy against arthritis and synovitis.
Seroprevalence of Hepatitis C Virus in Jinan, China, 2008–2020
Authors: Xu Mingjie , Liu Fang , Zhao Qianqian , Zhou Yunying , Zhuang Yuanmei , Ji Mingyu 
Published: June 2022

Abstract
Background:
Updated estimate of anti-HCV prevalence is critical for developing strategies to manage or eliminate HCV infection. To achieve this, a comprehensive study was conducted for the seroprevalence of HCV among patients in Jinan Central Hospital, China.
Methods:
From 2008 to 2020, 365,210 patients were tested for anti-HCV, core antigen of Hepatitis C Virus (HCV cAg), hepatitis B surface antigen (HBsAg), syphilis antibody (anti-TP), HIV antigen + antibody (Ag + Ab) assays, antiHAV IgM and antiHEV IgM.
Results:
The HCV seroprevalence was 0.79%. HCV seroprevalence is related to age distribution, the children (< 18 years) had a lower HCV seropositivity 0.15%, and among adults (≥ 18 years) was 0.81%. A increasing prevalence of HCV was found in adults aged greater than or equal to 41 years, the HCV seropositivity for those aged between 41 to 80 accounted for 74.56% of all seropositiveindividuals. Surprisingly, rate of HCV-HIV co-infection was 0. The HCV seroprevalence of patients in Kidney Disease Unit & Dialysis Department was much higher than patients in other departments, whether in inpatients or outpatients.
Conclusions
A lower HCV seroprevalence in Jinan, but a higher HCV seroprevalence in Kidney Disease Unit & Dialysis Department, especially in patients on hemodialysis.
Gorham-Stout syndrome: a chylothorax disease with massive bony destruction
Authors: Hong Ping-Yang , Zhang Xiao-Bin , Zhao Yi-Lin , Huang Mao-Hong , Zeng Hui-Qing 
Published: June 2022

Abstract
Gorham–Stout syndrome is a sporadic condition characterized by a tumor-like lesion with extensive osteolysis, severe symptoms, and a poor prognosis. Poor prognostic indicators include osteolytic lesions of the spine and pleura effusion. We presented a case in which the condition first manifested itself at the age of 67, with exacerbated shortness of breath. The patient's imaging studies (CT scan, MRI, and PET/CT) revealed osteolytic lesions (the skull, several spines, several ribs, both shoulder blades, and the pelvis). After a tissue biopsy of the spine, postoperative pathology revealed that a portion of the bone had been replaced by lymphatic-derived endothelial cells that stained positive for D2-40. The tests permitted parasitosis, thyroid or parathyroid disease, parasitosis, lymphoma, neoplasia, or an autoimmune problem to be ruled out. On the patient, we performed a superior vena cava angiography. There was an abnormal expansion of the azygos vein into the superior vena cava, as well as local contrast agent retention. The injection of zoledronic acid was used to prevent bone loss. After the therapy, his shortness of breath was greatly reduced. He experienced ongoing shortness of breath alleviation during the 2-month follow-up visit.
Theoritical Study of Channel Coded Secured Nano Communication Network in QCA Platform.
Authors: TAPNA SUPARBA , Chakrabarti Kisalaya , Mukhopadhyay Debarka 
Published: June 2022

Abstract
QCA “Quantum Dot-Cellular Automata” is another nano-technology model, that fills in an elective answer for CMOS that have numerous actual cutoff points and heaps of hardware limits. QCA is a semiconductor less innovation as well as data is passed dependent on electron charge and by common electrostatic repugnance among them. QCA has exceptionally higher gadget thickness, quicker exchanging speed timing and very low force utilization. QCA circuits in cryptographic application may assume a significant part. Both unscrambling as well as encryption measure is executed utilizing rationale circuit based on QCA. The research paper depicts fundamental method for creating cipher text in QCA, which may be useful in secure nanocommunication based on QCA.In secured encryption it is finding the realistic way in a secured authentication. The results’ execution along with testing is carried out by utilizing QCA Designer-2.0.3 tool.
Quality of Work Life of Magnetic Resonance Imaging Technologists: A Cross-Sectional Study
Authors: AlMugren Ghadah , Zedan Haya 
Published: June 2022

Abstract
Background: Quality of Work Life (QWL) is a multi-dimensional discipline that is concerned with the quality of life (QoL) at the workplace. This study aimed to assess the QWL level and identify the correlation between QWL dimensions and Job and Career Satisfaction (JCS). Methods: We used the 32-item WRQoL-2 tool, a questionnaire consisting of 6 subscales: Job and Career Satisfaction (JCS), Control at Work (CAW), Home-Work Interface (HWI), General Well-Being (GWB), Stress at Work (SAW), and Work Conditions (WCS), to collect data between October 2019 and December 2019. Results: 57 MRITs (100%) responded to the questionnaire. We found a high level of QWL among MRITs (66.2%, 3.31/5). The level of the JCS was high (71.6%, 3.59/5), with a significant correlation between the JCS and WCS, CAW, HWI, and GWB. An inverse relationship was noted between SAW and JCS. Conclusion: Further research on QWL is advised to diagnose and provide recommendation to resolve issues that may adversely affect the quality of healthcare service provision.
Validation of Low-Density Lipoprotein Cholesterol Equations in Pediatric Population
Authors: ZARARSIZ GÖZDE ERTÜRK , BOLAT SERKAN , CEPHE AHU , KOCHAN NECLA , YERLİTAŞ SERRA İLAYDA , DOĞAN HALEF OKAN , ZARARSIZ GÖKMEN 
Published: June 2022

Abstract
Purpose
This study aimed to validate different low-density lipoprotein cholesterol (LDL-C) estimating equations in the Turkish population, composed of children and adolescents.
Methods
In this study at Sivas Cumhuriyet University Hospital in Sivas (Turkey), a total of 3,908 children under the age of 18 were included. LDL-C was directly measured by direct homogeneous assays such as Roche, Beckman, and Siemens and was predicted by Friedewald’s, Martin-Hopkins’, extended Martin-Hopkins’ and Sampson’s formulas. Firstly, the concordances between the predictions obtained by the direct measurements and formulas were calculated, and then, these results were evaluated both overall and separately for the LDL-C, triglycerides (TG), and non-high-density lipoprotein cholesterol (non-HDL-C) sublevels. Linear regression analysis was performed, and residual error plots were generated between each prediction and direct measurement method. Coefficient of determination (R2) and mean absolute deviations were also evaluated.
Results
The overall concordance of the Friedewald, Sampson, Martin-Hopkins and the extended Martin-Hopkins formula were 64.6%, 69.9%, 69.4%, and 84.3% for the Roche direct assay, 69.8%, 71.6%, 73.6% and 80.4% for the Siemens direct assay, 66.5%, 68.8%, 68.9% and 82.1% for the Beckman direct assay, respectively. The extended Martin-Hopkins formula had the highest concordance coefficient in both overall and all sublevels of LDL-C, non-HDL-C, and TG. When estimating the LDL-C categories, the highest underestimation degrees were obtained with the Friedewald formula.
Conclusions
Our analysis, conducted in a large pediatric population, showed that the extended Martin-Hopkins equation gives more reliable results in predicting LDL-C compared to other equations.
Internal benchmarking and investigation to formulate practical innovations in the Moroccan construction industry
Authors: Gartoumi Khalil Idrissi , Aboussaleh Mohamed , Zaki Smail 
Published: June 2022

Abstract
The renovation of the Architecture, Engineering, Construction and Owner Operators (AECOO) industry is at the forefront of countries' concerns. Despite its important place in national economies, it suffers from several challenges. Faced with this paradox, rethinking inspiration has not attracted many countries like Morocco. Any improvement must be based on a thorough analysis for efficient solutions. In this context, the main objective of this paper is to trigger, investigate, and analyse the state and paradoxical aspects of the Moroccan construction industry (MCI). A triangular approach was conducted, consisting of a literature review, official documents, and a survey of 25 professionals and 15 academics in the sector. The results reveal two main failures, one is managerial and the other technological, and the enumeration of ambitions which are also conditioned by the emergence of technology and new managerial approaches. These findings provide a platform for understanding future interventions, support the literature and suggest avenues of research for neighbouring construction industries, developing countries, and Africa due to similarities with Morocco. Furthermore, it provides recommendations for future studies, especially a new research framework for MCI and other similar countries based on the implementation of Building Information Modelling and Lean Construction.
Exosomes released from macrophages infected with Talaromyces marneffei activate the innate immune responses and reduce intracellular multiplication
Authors: Ji Guangquan , Ren Hong , Feng Shan , Wang Hua , Chen Renqiong 
Published: June 2022

Abstract
Recent studies have shown that exosomes are involved in pathogenesis and in the treatment of various tumors and inflammatory diseases. We examined the impacts of exosomes released from Talaromyces marneffei (T. marneffei)-infected macrophages on human macrophages to determine whether they play a role in the pathogenesis of T. marneffei infection. Exosomes derived from macrophages were extracted using commercial kits and characterized by transmission electron microscopy and western blot. Further, we examine exosomes that regulate IL-10 and TNF-α production and activation of p42 and p44 extracellular signal-regulated kinase 1 and 2 (ERK1/2) and activation of autophagy. We found that exosomes induced activation of ERK1/2 and autophagy, IL-10 and TNF-α production in human macrophages. Furthermore, exosomes decreased the replication of T. marneffei in T. marneffei-infected human macrophages. Interestingly, exosomes isolated from T. marneffei-infected but not from uninfected macrophages can stimulate a proinflammtory response in resting macrophages. Our studies are the first to demonstrate that exosomes isolated from T. marneffei-infected macrophages can induce a proinflammatory response, and we hypothesize that exosomes play significant roles in activation of ERK1/2 and autophagy, the replication of T. marneffei and cytokine release during T. marneffei infection.