bluuebunny/crossref_metadata_2025_split huggingface dataset:
Contact Characteristics of Knee-joint Cartilage During Gait Based on
Finite Element Analysis
Authors: Liu Geng , Fu Pengge , Zhang Li , Yan Yuzhou , Wang Yuxin , Li Hui 
Published: December 2022

Background:
As a common clinical disease, knee osteoarthritis (KOA) is characterized
by chronic changes and articular cartilage wear, while the in vivo cartilage contact characteristics
of the knee joint during walking are still unclear. It is difficult to implement real-time assistance
and treatment for KOA patients accurately.

Objective:
To investigate the contact biomechanics of knee cartilage during gait and predict the
mechanism and location of cartilage damage, aiming to provide theoretical support for real-time
rehabilitation assistance for KOA patients.

Method:
In this study, the subject-specific finite element (FE) method was used to predict the
contact characteristics during the stance phase of the gait. A healthy volunteer prepared an intact
geometric left knee model based on magnetic resonance scans. The kinematic and dynamic data
were collected in a gait experiment and simulated using the personalized musculoskeletal model.

Results:
Throughout the gait cycle, the contact pressure, contact area and principal Green-
Lagrangian strain in the tibiofemoral joint show two obvious peaks concentrated on the 25% and
75% stance phase. The maximum values were 15.32 MPa, 400.607 mm2, and 24.35% on the tibial
side, while 15.58 MPa, 683.538 mm2, and 29.68% on the femoral side, respectively. The contact
characteristics were significantly greater in the medial compartment than in the lateral.

Conclusion:
A FE simulation method was developed in this study to forecast the contact characteristics
of the human knee joint. The prevention, rehabilitation, and treatment of KOA should
focus more on the medial compartment close to the intercondylar eminence, both for the femoral
and tibial cartilages.
The Web-Based Advance Care Planning Program “Explore Your Preferences for Treatment and Care”: Development, Pilot Study, and Before-and-After Evaluation
Authors: van der Smissen Doris , Rietjens Judith A C , van Dulmen Sandra , Drenthen Ton , Vrijaldenhoven-Haitsma F Ragnhild M D , Wulp Marijke , van der Heide Agnes , Korfage Ida J 
Published: December 2022

Background
Web-based advance care planning (ACP) programs may support patients in thinking about and discussing their preferences for future treatment and care. However, they are not widely available, and only a limited number of programs are evidence based.

Objective
We aimed to develop and evaluate an evidence-based, interactive web-based ACP program that guides users through the process of thinking about, discussing, and recording of preferences for treatment and care.

Methods
The program “Explore your preferences for treatment and care” was developed, pilot-tested on feasibility, and subsequently evaluated; engagement in ACP was assessed before program completion and 2 months after program completion using the ACP Engagement Survey (score 1-5) among 147 persons with chronic disease. Usability (score 0-100) and user satisfaction (score 1-5) were also assessed.

Results
ACP engagement increased from 2.8 before program completion to 3.0 two months after program completion (P<.001); contemplation about ACP increased from 2.6 to 2.8 (P=.003), and readiness for ACP increased from 2.2 to 2.5 (P<.001). No changes were found for knowledge about ACP (3.0-3.2; P=.07) and self-efficacy for ACP (3.8-3.8; P=.25). The program was perceived as usable (mean 70, SD 13), attractive (mean 3.8, SD 0.7), and comprehensible (mean 4.2, SD 0.6).

Conclusions
We developed an evidence-based, interactive web-based ACP program in cocreation with patients, relatives, and health care professionals. Before-and-after evaluation showed that the program can support people in taking first steps in ACP and in reflecting on preferences for treatment and care, by guiding them through the process of ACP using a stepwise approach. Participants perceived the program as usable and understandable, and they were satisfied with the program and with the amount of information. Health care professionals may use the program as a tool to start ACP discussions with their patients. The program may increase awareness of ACP.
PHARMACOKINETIC PREDICTIONS AND MOLECULAR DYNAMIC ANALYSIS OF TERPENOID AND FLAVONOID COMPOUNDS FROM MIANA LEAVES (PLECTRANTHUS SCUTELLARIOIDES (L.) R. BR.) AS AN ANTIMALARIAL CANDIDATES ON PLASMEPSIN II RECEPTOR
Authors: TJITRARESMI AMI , APRIALI KIRKA DWI , NURVIANITA KAMILA , MUSFIROH IDA , MOEKTIWARDOYO MOELYONO , SUSILAWATI YASMIWAR 
Published: December 2022

Objective: This study aims to find antimalarial candidates from 32 terpenoids and three flavonoid compounds found in miana leaves in silico using plasmepsin protein as a receptor through docking simulations, molecular dynamics simulations, and pharmacokinetic predictions.
Methods: The research was conducted in silico through molecular docking simulation, molecular dynamic simulations, analysis of potential compounds using Lipinski’s rule, and prediction of ADMET based on ligands.
Results: The results showed isophytol had the best interaction with the plasmepsin II based on the low free binding energy (FBE) and led to hydrogen bonding with the plasmepsin II crucial amino acid, Asp34. Isophytol has the best result in molecular dynamic simulation. Based on pharmacokinetics predictions, toxicity, and Lipinski’s rule of five, most tested compounds, including isophytol, meet the criteria as a promising drug.
Conclusion: Isophytol from miana leaves with plasmepsin II protein has the best and most stable interaction based on the results of molecular dynamic simulation, so this compound was a candidate for antimalarial drugs.
Check Cystoscopy Follow-up Practice for Low-Risk (pTa) Non-muscle Invasive Bladder Cancer in the United Kingdom
Authors: Al-Khafaji Ibrahim , Abed Omar Al-Mula 
Published: December 2022

Objectives: To identify the best practice policy and guideline for surveillance with check cystoscopies follow up for low-risk pTa urothelial bladder tumour and to identify the recurrence rate and the progression rate of low-risk urothelial bladder tumour and how safe is it to discharge them at 1- versus 5-years of follow up. Objectives: To identify the best practice policy and guideline for surveillance with check cystoscopies follow up for low-risk pTa urothelial bladder tumour and to identify the recurrence rate and the progression rate of low-risk urothelial bladder tumour and how safe is it to discharge them at 1- versus 5-years of follow up. Secondary outcome: To estimate the cost-effectiveness of a reduced follow-up scheme, if this is deemed a safe practice to follow. Methodology: It is a single centre, retrospective review of all low-risk NMIBC patients diagnosed with low-risk bladder tumors at our Trust between 2012 and 2014 from our local urological cancer multi-disciplinary team (MDT) registry and ensured a 5-year time-lapse from diagnosis. Histology grade and staging from the first TURBT, receiving of mitomycin within 24 hrs following the initial TURBT, the timing of cystoscopy follow-up, cystoscopy findings (evidence of recurrence), further procedures (bladder biopsy, fulguration or TURBT), histology of further procedures, recurrence rate and time from the first TURBT to discharge to primary care are reviewed and analysed. Result: Our initial review revealed a high likelihood of recurrence (33.9%) in the low-risk NMIBC patients after 12 months of being cancer free. It also demonstrated that there is further progression in (23.8%) of those who had a later recurrence despite being asymptomatic. Conclusion: We would recommend a 5-year follow-up surveillance and further national collaboration to audit this patient subgroup to define a safe period of cystoscopic follow-up for these patients and bring further evidence for NICE to build up their recommendations.
The Radical Reformation of the Reorganization of the Restoration: Recent Changes in the RLDS Understanding of the Book of Mormon
Authors: Midgley Louis 
Published: December 2022

Abstract
Beginning in the 1960s, the Reorganized Church of Jesus Christ of Latter Day Saints (RLDS) has modified its understanding of the Book of Mormon and Joseph Smith’s prophetic charisms. Where the RLDS were earlier permitted to do this, they are now encouraged by their leaders to read the Book of Mormon as nineteenth-century fiction, though they are still permitted to find in it, if they wish, some inspiring passages. These changes have been resisted by a conservative minority that has lost the battle for control of the Reorganization and now tends to worship outside RLDS congregations. A few Latter-day Saints have also begun to read the Book of Mormon as fiction. Their efforts to turn the Book of Mormon into nineteenth-century fiction have been opposed by competent Latter-day Saint scholarship, though not without resistance from those who control "independent" and "liberal" publishing ventures.
The Latest Straw Man
Authors: Hamblin William J. 
Published: December 2022

Abstract
The failure of those who reject the historicity of the Book of Mormon to respond cogently to the increasing body of evidence and argument supporting historicity is becoming painfully apparent. Stephen E. Thompson’s recent review of Review of Books on the Book of Mormon 6/1 (1994) is one of the most recent examples of this "straw man" approach.
Narrative Criticism and the Book of Mormon
Authors: Snow Edgar C. 
Published: December 2022

Abstract
This paper suggests the use of narrative criticism, a recent literary interpretive tool, as a favorable method of Book of Mormon interpretation. As an example of narrative interpretation, the Samuel the Lamanite narrative in Helaman 13–16 is analyzed as a discrete narrative portion of the Book of Mormon for the exploration of the possibilities of a narrative critical approach to its text. Instead of focusing on the content of Samuel’s exhortations, lamentations, and prophecies in order to understand these passages, I interpret the surrounding narrative and find it serves as an impressive complement to the doctrinal content of Samuel’s discourse.
The Book of Mosiah: Thoughts about Its Structure, Purposes, Themes, and Authorship
Authors: Sturgess Gary L. 
Published: December 2022

Abstract
The book of Mosiah is a cultic history of the reign of Mosiah, structured around three royal ceremonies in 124, 121, and 92–91 B.C. On each of these occasions, newly discovered scriptures were read to the people, stressing the dangers of monarchical government and celebrating the deliverance of the people and the revelation of Jesus Christ. This book existed independently hundreds of years before Mormon engraved it onto the gold plates. The most likely occasion for the writing of such a book was in the aftermath of Mosiah’s death when Alma the Younger needed to undermine the Amlicite bid to reestablish the monarchy.
Teaching Advanced Data Analytics, Robotic Process Automation, and Artificial Intelligence in a Graduate Accounting Program
Authors: Ng Cory 
Published: December 2022

ABSTRACT
Technological advances in data analytics, robotic process automation (RPA), and artificial intelligence (AI) are transforming businesses and redefining what skill sets are needed in the accounting profession. To prepare students, academic accounting departments must develop strategies to integrate data analytics and emerging technologies into the curriculum. This paper discusses the design process used in a graduate-level advanced data analytics course that incorporates RPA and AI at a public university in the northeastern region of the United States. The paper concludes with a statistical analysis of precourse/postcourse student reflections and feedback surveys as part of a quality assurance initiative. The results suggest strong evidence of student learning related to the course learning objectives.
Masjid Jami At-Taqwa Sebagai Cagar Budaya di Desa Gumelem Kecamatan Susukan Kabupaten Banjaranegara
Authors: Mutaqin Enjen Zaenal , Putri Fatma 
Published: December 2022

Masjid dalam sejarahnya mempunyai arti penting dalam kehidupan umat Islam. Awal mula berdirinya masjid adalah pusat untuk beribadah, pengajian, pembelajaran Qur’an dan Sunnah serta sebagai tempat pembelajaran hukum-hukum Islam. Bangunan masjid adalah salah satu bentuk dari kebudayaan agama islam karena di dalamnya terdapat perpaduan fungsi bangunan masjid sebagai unsur arsitektur Islami, seiring berkembangnya zaman, model arsitektur bangunan semakin modern, bagi masyarakat bangunan masjid yang megah dan indah menjadi salah satu hal yang menarik. Artikel ini bertujuan untuk menjabarkan tentang keunikan arsitektur masjid Jami At-Taqwa di desa Gumelem kulon dan fungsinya bagi masyarakat sehingga masjid ini masuk dalam kategori cagar budaya di Kabupaten Banjarnegara. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan pendekatan deskriptif. Teknik pengumpulan data yang dilakukan adalah dengan cara wawancara dan observasi. Penelitian ini memperoleh hasil bahwa Masjid Jami At-Taqwa merupakan salah satu simbol peradaban islam di Jawa khususnya di Kabupaten Banjarnegara. Fungsi masjid jami at-taqwa sudah sangat sesuai dengan yang telah dilakukan oleh Rasululloh SAW yaitu menjadi tolak ukur dan tempat ibadah bagi seorang muslim, salah satu fungsi yang menarik adalah masjid ini dijadikan sebagai wisata religi.
Altruisme relawan palang merah indonesia kabupaten kudus dalam penangulangan bencana
Authors: Putra Muhammad Eka , Salsabila Natasya , Setyani Ira , Widjanarko Mochamad 
Published: December 2022

AbstractA volunteer within the PMI organization is someone who carries out red cross activities either permanently or not in accordance with the basic principles of the International Red Cross and Red Crescent Movement and is organized by the Indonesian Red Cross (PMI). There are no special characteristics that describe PMI volunteers, PMI volunteers consist of KSR members at universities, PMRs in elementary and middle schools and TSR from the community in general. This study uses a qualitative method of phenomenological description to see the factors of the altruism nature of Indonesian Red Cross volunteers in the Kudus district in disaster management. Collecting data using observation and interviews with 3 resource persons taken from PMI volunteers in Kudus district. Through this study, it was found that PMI volunteers in Kudus district had mood factors, empathy, belief in social justice, sociobiological factors and situational factors in accordance with existing theories by the altruism factorAbstrakRelawan dalam lingkungan organisasi PMI adalah seseorang yang melaksanakan kegiatan kepalangmerahan baik secara tetap maupun tidak tetap sesuai dengan prinsip-prinsip dasar Gerakan Palang Merah dan Bulan Sabit Merah Internasional serta diorganisasikan oleh Palang Merah Indonesia (PMI). Tidak ada ciri khusus yang menggambarkan relawan PMI, relawan PMI terdiri dari anggota KSR yang ada di universitas, PMR yang ada di sekolah dasar, dan menengah serta TSR yang berasal dari masyarakat secara umum. Dalam penelitian ini menggunakan metode kualitatif deskripsi fenomenologi untuk melihat faktor dari sifat altruisme relawan Palang merah Indonesia di akbupaten kudus dalam penanggulangan bencana. Pengambilan data menggunakan observasi dan wawancara terhadap 3 narasumber yang diambil dari relawan PMI yang ada di kaabupaten Kudus. Melalui penelitian ini, didapatkan hasil bahwa Relawan PMI kabupaten Kudus memiliki faktor suasana hati, empati, meyakini keadilan sosial, faktor sosiobiologi serta faktor situasional sesuai dengan teori yang telah ada oleh faktor Altruisme
Type 2 diabetes mellitus, physical activity, and neuromusculoskeletal complications
Authors: Jena Debasish , Sahoo Jagannatha , Barman Apurba , Behera Kishore Kumar , Bhattacharjee Souvik , Kumar Sanyal 
Published: December 2022

Objectives:
The objectives of the study were to investigate the neuromusculoskeletal complications of Type 2 diabetes mellitus (T2DM) and their associated factors, including the level of physical activity (PA) and clinicodemographic characteristics.

Materials and Methods:
In this cross-sectional analysis, we included 370 participants diagnosed with T2DM for no <1 year who satisfied the inclusion and exclusion criteria. Demographic and clinical characteristics were noted and a thorough clinical examination was performed on all the participants. International PA Questionnaire-Short Form was used to evaluate the level of PA of the participants. The continuous data is presented as mean ± SD and the categorical data is presented as the number of participants (n) and percentage (%). A logistic regression model was used to investigate the predictors for the prevalence of the complications.

Results:
The mean duration of T2DM was 7.32 ± 5.53 years and the mean hemoglobin A1C (HbA1c) level (%) was 8.16±1.67. A majority of the participants were having uncontrolled diabetes with an HbA1c level ≥7.5% (n = 190; 51.35%). The level of PA was low in a substantial proportion of the participants (n = 276; 74.59%). A total of 162 (43.78%) participants were diagnosed with neuromusculoskeletal complications. Low back pain was the most common complication and degenerative disk disease was the most common diagnosis overall. Longer duration of diabetes, poor glycemic control, and low PA were associated with the prevalence of neuromusculoskeletal complications (P < 0.05).

Conclusion:
Neuromusculoskeletal complications of T2DM are common and can result in significant disability in this population. Low PA is very common among T2DM patients and an important contributor to the development of complications. Health-care providers should consider PA an integral component of the management protocol for T2DM patients.
Effects of two different radiotherapies for craniopharyngiomas using stereotactic radiosurgery/ stereotactic radiotherapy or fractionated stereotactic radiotherapy
Authors: Kamogawa Misaki , Shuto Takashi , Matsunaga Shigeo 
Published: December 2022

Background:
Numerous studies have reported about good tumor control with both stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (FSRT) for residual and recurrent craniopharyngiomas, but no studies have reported on the appropriate use of different types of radiation modalities. This study aimed to report the outcomes of SRS/stereotactic radiotherapy (SRT) or FSRT and compare tumor control in a single center.

Methods:
From 2014 when TrueBeamTM STx with Novalis was introduced in our hospital to 2021, 21 patients underwent SRS/SRT or FSRT with gamma knife surgery (GKS) and Novalis. We have selected the radiation modalities considering mainly the distance of the optic nerve and chiasm. Imaging and clinical follow-up data were sent and reviewed.

Results:
The mean age was 52 years and there were 11 men. Of the 21 total patients, three experienced SRS (GKS, 50% isodose 12–15 Gy), five underwent SRT (GKS or Novalis, 19.5–24 Gy 3 fractions), and 13 patients underwent FSRT (Novalis, 54 Gy 30 fractions). The median follow-up was 32.6 (range 17–44) months after SRS/SRT and 34.0 (range 4–61) months after FSRT. In the SRS/SRT group, the mean tumor volume decreased from 1.103 to 0.131 cm3 (P < 0.01), and in the FSRT group, from 3.015 to 1.012 cm3 (P < 0.01). No radiation-induced optic neuropathy and other acute toxicity occurred.

Conclusion:
Craniopharyngioma can be expected to have very good tumor control by selecting SRS/SRT or FSRT depending on the distance between the optic nerve and the tumor.
Shopping Life Style dan Stimulus Media Iklan Terhadap Ekpetasi Pelanggan (Studi Kasus Produk Fashion)
Authors: Kuspriyono Taat 
Published: December 2022

As a woman, of course there is a desire to buy and try various desired products. This is not strange considering that as a woman, of course, you want to look elegant and beautiful. Before buying, of course, someone will be presented with various ad impressions that are intended to carry out promotional activities with the aim of making the goods sell well in the market. To prove this, the researchers carried out further research activities using quantitative research methods. Data collection is done by first distributing questionnaires to the informants. After the questionnaire data was collected, the data was then processed using SPSS software. The results of the study show that there is a positive and significant influence between Shopping Life Style and Advertising Media Stimulus on Customer Expectations (Case Study of Fashion Products).
Keywords: Shopping Lifestyle and Advertising Media Stimulus, Customer Expectations
Karakteristik Legislatif dan Ketepatwaktuan Anggaran: Studi Empiris pada Pemerintah Daerah di Indonesia
Authors: Muhtar  
Published: December 2022

This study aims to examine the effect of local legislative characteristics on the timeliness of local government budgets in Indonesia. Using secondary data from the authorized institutions, this study generates 2032 observations covering all local governments in Indonesia during 2015-2018 that were analyzed using multiple linear regression. The research findings show that most local governments in Indonesia have been able to validate the Local Revenue and Expenditure Budget (APBD) on time, although there are still several local governments that are late by exceeding the deadline of the APBD validation date. Furthermore, the analysis results reveal that legislative political competition has a negative effect on local government budgeting timeliness while legislative size has a positive effect. However, this study finds no significant effect of legislative gender representation considering the relatively low political representation of women in the Regional People's Representative Council (DPRD). From the analysis results obtained, this study emphasizes that the DPRD as the people’s representation must always maintain the quality of supervision in the preparation of the budget even though there is political competition and differences in interests. The people should also increase the representation of women in the DPRD to support equality and support the implementation of DPRD functions. In addition, local governments must also have an adequate number of DPRD members as needed. Thus, local governments can fulfill the timeliness of the APBD validation as a form of local government financial accountability.
Keywords: local government; budgeting timeliness; political competition; gender representation; legislative size
THE INFLUENCE OF ORGANIZATIONAL CULTURE, WORK MOTIVATION, LEADERSHIP AND WORK ENVIRONMENT ON THE PERFORMANCE OF KSPPS BMT BIF BINA IHSANUL FIKRI EMPLOYEES IN YOGYAKARTA CITY
Authors: Romli Ahmat Nazom , Fitroh Adhilla  , Abdul Cholid Hidayat  
Published: December 2022

Objectives: this study aims to determine the influence of organizational culture, motivation, leadership, and work environment on the performance of BMT Bina Ihsanul Fikri employees in Yogyakarta.
Method: The population in this study was BMT Bina ihsanul fikri employees in Yogyakarta city which amounted to 90 employees and the sample used was 90 employees with a = 0.05 and used the jenih sample method. The data used questionnaires.
Analysis tools : Data used multiple regression multiple multiple liniear.
The results of the study: the findings of this study show that organizational culture, work motivation, leadership and work environment have a significant effect on the performance of KSPPS BMT Bina Ihsanuk Fikri Yogyakarta employees. Organizational culture has a positive influence on performance. Work motivation has a negative influence on employee performance. Leadership has a positive influence on employee performance. The work environment has a positive influence on employee performance