bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENERIMAAN DAN RESISTENSI TERHADAP KEBIJAKAN PENATAAN TRANSPORTASI ANGKUTAN UMUM DI KOTA BANDUNG
Authors: Edie Arif Moelia 
Published: January 2022

This study aims to explain the implementation of public transportation management policies by the Bandung City Government, particularly from the perspective of public acceptance and resistance to government policies. With a qualitative research design, it was found that the policy implementation encountered obstacles of low enthusiasm and less public acceptance. The policy does not create new substantial things, so people consider it only to replace the old situation. As a result, the process of change is slow, and it only becomes a circular and incremental change. To improve the policy, it is necessary to make binding rules in the form of mayor regulations on minimum standards for public transport services and regional regulations on transportation development master plans as guidelines in restructuring public transport routes so that they do not overlap.
Keywords: Policy Implementation; Public Acceptance; Public Resistance; Public Transportation Arrangement
EVALUASI KELEMBAGAAN PERANGKAT DAERAH KABUPATEN KUNINGAN
Authors: Sinaga Jona Bungaran Basuki 
Published: January 2022

This study evaluates the organizations, identifies the potential primary functions, and redesigns the institution of Kuningan Regency Government. The research design is qualitative, and the discussion is carried out by combining theoretical and legal analyses. The results present that the structural arrangement and task distribution within the organizations do not result in a harmony to achieve the development mission. The institutional design should refer to the regional vision and mission emphasizing on three primary functions: agriculture; tourism; environment. For this reason, it should pay attention to the strengthening and harmonizing the offices of agriculture, tourism, and environment, as well as those responsible in delivering education, health, public works and spatial planning, public housing and settlement, public order and social functions.

Keywords: Restructurization; Institutions; Local Department
THE ROLE OF THE TASKS IN IMPLEMENTING COMMUNITY ACTIVITIES RESTRICTIONS (PPKM) HANDLING COVID-19 IN SELAAWI DISTRICT, GARUT REGENCY
Authors: Firdaus Akbar Lucky , Pramudana Putri Dea Apsari , Suroso Arif Farhan 
Published: January 2022

The purpose of this Field Practice Activity is to assess the efficiency of the COVID-19 task force's implementation in Selaawi District in dealing with COVID-19 and residents who have been proven positive for COVID-19. The Garut Regent's Decree establishes a Task Force for the Enforcement of Community Activity Restrictions in Selaawi District, Garut Regency. The technique that was used a Literature Review and the roadblocks that it faces, including measures to restrict the spread of the corona virus, which have not been maximized. People are progressively disobeying 3M's health recommendations, such as wearing masks, cleaning their hands with soap, and keeping a safe distance. The large-scale social restriction (PSBB) strategy has aided the implementation of physical distance in Indonesia since the start of the pandemic. The remedy to this problem is to enforce 3M (masks, distance, and hand washing) in a systematic manner, as well as passively 3T (testing, tracing, and treatment) and raise public awareness about the necessity of health procedures through the COVID-19 task force. In this method, the handling efforts can yield the best results and have been successful in lowering positive numbers and lowering deaths.
Keywords: COVID-19, Emergency, Society, Implementation
PERAN SATUAN POLISI PAMONG PRAJA DALAM MENERTIBKAN MINUMAN BERALKOHOL DI KABUPATEN INDRAMAYU PROVINSI JAWA BARAT
Authors: Firdaus Restu Agung , Fadhilah Hasna Azmi 
Published: January 2022

Problems regarding the role of the Civil Service Police Unit which are not running optimally so that it has an impact on peace and public order, namely the discovery of traders and consumers of alcoholic beverages due to lack of socialization and operations often used by traders and consumers to continue to circulate and consume. In connection with the research analysis, the authors use the theory of Biddle and Thomas. While the method used is descriptive qualitative. The data collection techniques used by interview, documentation and observation. From the results of the study, it was found that the Civil Service Police Unit was not optimal in carrying out its role. One of them is the enforcement of regional laws and regulations, which is still found abuse of alcoholic beverages, with indicators of weak supervision and weak faith of the people of Indramayu Regency itself. The efforts that have been made by the Indramayu Regency Civil Service Police Unit are through the development of members, the formation of Civil Servant Investigators, capacity building of employees, and supporting physical facilities.
IMPLEMENTASI PENERAPAN DISIPLIN DAN PENEGAKAN HUKUM PROTOKOL KESEHATAN SEBAGAI UPAYA PENCEGAHAN DAN PENGENDALIAN COVID-19 DI KABUPATEN MAGELANG PROVINSI JAWA TENGAH
Authors: Anggraini Anggita Bayu 
Published: January 2022

Implementasi penerapan disiplin dan penegakan hukum protokol kesehatan sebagai upayapencegahan dan pengendalian COVID-19 di Kabupaten Magelang Provinsi Jawa Tengahmerupakan penelitian yang bertujuan untuk mendapatkan gambaran penegakan protokolkesehatan di Kabupaten Magelang serta mengetahui faktor penghambatnya. Penelitian inimenggunakan teori implementasi Edward III yang dilakukan berdasarkan empat variable,yaitu (1) Komunikasi, (2) Sumber Daya, (3) Disposisi, dan (4) Stuktur Birokrasi. Metodeyang digunakan untuk menganalisis data adalah dengan teknik analisis deskriptif kualitatifdengan cara eksploratif. Pengumpulan data menggunakan tiga alat penelitian, yakni;wawancara, observasi, dan analisis. Hasil analisisnya adalah: (1) Kesadaran masyarakatyang rendah menyebabkan penerapan protokol kesehatan menjadi tidak maksimal 2) Sanksiyang diberlakukan tidak memberikan efek jera. (3) Keterbatasan Anggaran. Berdasarkanhasil tersebut, diperlukan kolaborasi proaktif dari semua unsur pemerintah pusat, pemerintahdaerah, serta masyarakat. Pengembangan inovasi dalam pencegahan persebaran COVID-19,serta sosialisasi agar dapat diterima secara ilmiah dikalangan masyarakat.
Kata Kunci: Implementasi, Protokol Kesehatan, COVID-19
PENCEGAHAN KEBAKARAN HUTAN DAN LAHAN DALAM RANGKA MELINDUNGI PEMUKIMAN MASYARAKAT DI KABUPATEN KOTAWARINGIN BARAT PROVINSI KALIMANTAN TENGAH
Authors: Ambarita Alexander 
Published: January 2022

Kondisi alam Kabupaten Kotawaringin Barat dengan hutan dan lahan gambut yang rawan menjadi penyebab terjadi kebakaran hutan dan lahan saat musim kemarau. Tujuan dari penelitian ini untuk mengetahui pencegahan kebakaran hutan dan lahan dalam rangka melindungi pemukiman masyarakat melalui Peran Badan Penanggulangan Bencana Daerah (BPBD) di Kabupaten Kotawaringin Barat. Penelitian ini menggunakan metode kualitatif deskriptif dengan pendekatan induktif. Teknik dalam pengumpulan data yaitu wawancara, observasi dan dokumentasi. Teknik yang digunakan dalam analisis data yaitu reduksi data, penyajian data, analisis SWOT dan penarikan kesimpulan. Temuan yang diperoleh penulis dalam penelitian ini yaitu pencegahan bencana kebakaran hutan dan lahan dilakukan melalui adanya peran utama dari BPBD di Kabupaten Kotawaringin Barat dengan membentuk satuan tugas (satgas) penanganan kebakaran hutan dan lahan yang berkoordinasi dengan TNI/POLRI, Masyarakat Peduli Api (MPA), Taruna Siaga Bencana (Tagana) dan manggala agni serta juga dengan memberikan sarana dan prasarana dalam pencegahan kebakaran hutan dan lahan berupa pompa air, selang pemadam, pendirian pos pemantauan titik api serta memberikan sosialisasi dan penyuluhan kepada masyarakat dalam mengatasi kebakaran hutan dan lahan. Faktor penghambat yaitu ada beberapa tempat yang sulit untuk menjangkau lokasi kejadian kebakaran, lahan gambut yang sulit diatasi dan musim kemarau panjang sehingga kekurangan sumber air untuk dilakukan pemadaman. Upaya yang dapat dilakukan dengan membuat embung atau kolam penampungan air dan membuat kanal dengan menggunakan alat berat exacavator sebagai alat utama sehingga sumber air mudah didapatkan dan merumuskan strategi melalui analisis SWOT. Kesimpulan penelitian adalahsecara garis besar peran BPBD dalam menangani bencana ini sudah sesuai dengan peraturan yang berlaku yaitu Undang-Undang Nomor 24 Tahun 2007, namun pada peIaksanaan terdapat beberapa kendala sehingga penulis memberikan saran yaitu, melakukan sosialisasi dan penyuluhan kepada masyarakat, melakukan koordinasi dengan BNPB dalam rangka pengadaan alat yang masih kurang seperti tabung oksigen bagi petugas penanganan kebakaran.
Kata Kunci : Peran; Pencegahan; Kebakaran Hutan dan Lahan
A Model for the Apparent Gas Permeability of Shale Matrix Organic Nanopore Considering Multiple Physical Phenomena
Authors: Guo Wei , Zhang Xiaowei , Yu Rongze , Kang Lixia , Gao Jinliang , Liu Yuyang 
Published: January 2022

The flow of shale gas in nano scale pores is affected by multiple physical phenomena. At present, the influence of multiple physical phenomena on the transport mechanism of gas in nano-pores is not clear, and a unified mathematical model to describe these multiple physical phenomena is still not available. In this paper, an apparent permeability model was established, after comprehensively considering three gas flow mechanisms in shale matrix organic pores, including viscous slippage Flow, Knudsen diffusion and surface diffusion of adsorbed gas, and real gas effect and confinement effect, and at the same time considering the effects of matrix shrinkage, stress sensitivity, adsorption layer thinning, confinement effect and real gas effect on pore radius. The contribution of three flow mechanisms to apparent permeability under different pore pressure and pore size is analyzed. The effects of adsorption layer thinning, stress sensitivity, matrix shrinkage effect, real gas effect and confinement effect on apparent permeability were also systematically analyzed. The results show that the apparent permeability first decreases and then increases with the decrease of pore pressure. With the decrease of pore pressure, matrix shrinkage, Knudsen diffusion, slippage effect and surface diffusion effect increase gradually. These four effects will not only make up for the permeability loss caused by stress sensitivity and adsorption layer, but also significantly increase the permeability. With the decrease of pore radius, the contribution of slippage flow decreases, and the contributions of Knudsen diffusion and surface diffusion increase gradually. With the decrease of pore radius and the increase of pore pressure, the influence of real gas effect and confinement effect on permeability increases significantly. Considering real gas and confinement effect, the apparent permeability of pores with radius of 5 nm is increased by 13.2%, and the apparent permeability of pores with radius of 1 nm is increased by 61.3%. The apparent permeability model obtained in this paper can provide a theoretical basis for more accurate measurement of permeability of shale matrix and accurate evaluation of productivity of shale gas horizontal wells.
Association Between Prediabetes and Erectile Dysfunction: A Meta-Analysis
Authors: Jin Mingyu , Yuan Shaoying , Wang Bo , Yi Luqi , Wang Chenxia 
Published: January 2022

BackgroundDiabetes has been associated with the increased risk of erectile dysfunction (ED). However, previous studies evaluating the association between prediabetes and ED showed inconsistent results. We performed a meta-analysis of observational studies to systematically evaluate the above association.MethodsRelevant observational studies were retrieved by search of PubMed, Embase, and Web of Science databases. A random-effect model which incorporated the potential intra-study heterogeneity was used for the meta-analysis. Subgroup analyses were performed to evaluate the influences of study characteristics on the outcome.ResultsNine studies (five matched case-control studies and four cross-sectional studies) were included. Age were adjusted or matched in all of the studies. Pooled results showed that compared to men with normoglycemia, men with prediabetes were associated with higher prevalence of ED (odds ratio = 1.62, 95% confidence interval: 1.28 to 2.07, P &lt; 0.001; I2 = 78%). Subgroup analyses showed that the association was not significantly affected by definition of prediabetes, diagnostic tool for ED, or controlling of additional variables besides age (both P for subgroup difference &gt; 0.05). However, the association between prediabetes and ED seemed to be stronger in case-control studies than that in cross-sectional studies, and in studies with younger men (mean age &lt; 50 years) than in those with older men (mean age ≥ 50 years; both P for subgroup difference &lt; 0.05).ConclusionsPrediabetes is associated with higher prevalence of ED, which may be independent of age of the males and may be stronger in young men.
Prescription of Physical Activity by General Practitioners in Type 2 Diabetes: Practice and Barriers in French Guiana
Authors: Dranebois Stephanie , Lalanne-Mistrih Marie Laure , Nacher Mathieu , Thelusme Liliane , Deungoue Sandra , Demar Magalie , Dueymes Maryvonne , Drak Alsibai Kinan , Sabbah Nadia 
Published: January 2022

BackgroundGeneral practitioners (GPs) are the major primary healthcare players in the management of type 2 diabetes. In addition to a well-balanced diet, physical activity (PA) appears as a necessary non-medicinal therapy in the management of diabetic patients. However, GPs emphasize several obstacles to its prescription. The aim of this study is to evaluate the practices, barriers, and factors favoring the prescription of PA in type 2 diabetic patients by GPs in French Guiana.MethodWe conducted a cross-sectional descriptive study using a questionnaire, designed to interview 152 French Guiana GPs and describe their practice in prescribing PA in type 2 diabetic patients.ResultsOur results revealed that the prescription of PA as a non-medicinal therapeutic choice in the management of type 2 diabetes was practiced by 74% of the French Guiana GPs. However, only 37% of GPs responded that they implemented the recommendations; indeed, only one-third knew about them. The majority of GPs were interested in PA training, but only 11% were actually trained in this practice. The lack of structure adapted to the practice of PA and the lack of awareness of the benefits of PA in metabolic pathology appeared as the main obstacles to PA prescription.ConclusionThis study highlights the importance of improving the training of GPs in the prescription of PA, the development of adapted PA structures, and collaboration between the different actors within the framework of the sport-health system in type 2 diabetes in French Guiana.
A Thrombomodulin Promoter Gene Polymorphism, rs2239562, Influences Both Susceptibility to and Outcome of Sepsis
Authors: Watanabe Eizo , Takasu Osamu , Teratake Youichi , Sakamoto Teruo , Ikeda Toshiaki , Kotani Joji , Kitamura Nobuya , Ohmori Masaaki , Teratani Ayako , Honda Goichi , Hatano Masahiko , Mayer Benjamin , Schneider E. Marion , Oda Shigeto 
Published: January 2022

Objective: Disseminated intravascular coagulation plays a key role in the pathophysiology of sepsis. Thrombomodulin is essential in the protein C system of coagulation cascade, and functional polymorphisms influence the human thrombomodulin gene (THBD). Therefore, we conducted a multicenter study to evaluate the influence of such polymorphisms on the pathophysiology of sepsis.Methods: A collaborative case-control study in the intensive care unit (ICU) of each of five tertiary emergency centers. The study included 259 patients (of whom 125 displayed severe sepsis), who were admitted to the ICU of Chiba University Hospital, Chiba, Japan between October 2001 and September 2008 (discovery cohort) and 793 patients (of whom 271 patients displayed severe sepsis), who were admitted to the five ICUs between October 2008 and September 2012 (multicenter validation cohort). To assess the susceptibility to severe sepsis, we further selected 222 critically ill patients from the validation cohort matched for age, gender, morbidity, and severity with the patients with severe sepsis, but without any evidence of sepsis.Results: We examined whether the eight THBD single nucleotide polymorphisms (SNPs) were associated with susceptibility to and/or mortality of sepsis. Higher mortality on severe sepsis in the discovery and combined cohorts was significantly associated with the CC genotype in a THBD promoter SNP (−1920*C/G; rs2239562) [odds ratio [OR] 2.709 (1.067–6.877), P = 0.033 and OR 1.768 (1.060–2.949), P = 0.028]. Furthermore, rs2239562 SNP was associated with susceptibility to severe sepsis [OR 1.593 (1.086–2.338), P = 0.017].Conclusions: The data demonstrate that rs2239562, the THBD promoter SNP influences both the outcome and susceptibility to severe sepsis.
Cytokine Hemoadsorption as Rescue Therapy for Critically Ill Patients With SARS-CoV-2 Pneumonia With Severe Respiratory Failure and Hypercytokinemia
Authors: Ruiz-Rodríguez Juan Carlos , Chiscano-Camón Luis , Ruiz-Sanmartin Adolf , Palmada Clara , Paola Plata-Menchaca Erika , Franco-Jarava Clara , Pérez-Carrasco Marcos , Hernández-González Manuel , Ferrer Ricard 
Published: January 2022

Introduction: A dysregulated inflammatory response, known as “cytokine storm”, plays an important role in the pathophysiology of coronavirus 2019 disease (COVID-19). Identifying patients with a dysregulated inflammatory response and at high risk for severe respiratory failure, organ dysfunction, and death is clinically relevant, as they could benefit from the specific therapies, such as cytokine removal by hemoadsorption. This study aimed to evaluate cytokine hemoadsorption as rescue therapy in critically ill patients with SARS-CoV-2 pneumonia, severe respiratory failure refractory to prone positioning, and hypercytokinemia.Methods: In this single center, observational and retrospective study, critically ill patients with SARS-CoV-2 pneumonia, severe acute respiratory failure, and hypercytokinemia were analyzed. All the patients underwent cytokine hemoadsorption using CytoSorb® (Cytosorbents Europe, Berlin, Germany). The indication for treatment was acute respiratory failure, inadequate clinical response to the prone position, and hypercytokinemia.Results: Among a total of 343 patients who were admitted to the intensive care unit (ICU) due to SARS-CoV-2 infection between March 3, 2020 and June 22, 2020, six patients received rescue therapy with cytokine hemoadsorption. All the patients needed invasive mechanical ventilation and prone positioning. A significant difference was found in the pre- and post-treatment D-dimer (17,868 mcg/ml [4,196–45,287] vs. 4,488 mcg/ml [3,166–17,076], p = 0.046), C-reactive protein (12.9 mg/dl [10.6] vs. 3.5 mg/dl [2.8], p = 0.028), ferritin (1,539 mcg/L [764–27,414] vs. 1,197 ng/ml [524–3,857], p = 0.04) and interleukin-6 (17,367 pg/ml [4,539–22,532] vs. 2,403 pg/ml [917–3,724], p = 0.043) levels. No significant differences in the pre- and post-treatment interleukin-10 levels (22.3 pg/ml [19.2–191] vs. 5.6 pg/ml [5.2–36.6], p = 0.068) were observed. Improvements in oxygenation (prehemoadsorption PaO2/FIO2 ratio 103 [18.4] vs. posthemoadsorption PaO2/FIO2 ratio 222 [20.9], p = 0.029) and in the organ dysfunction (prehemoadsorption SOFA score 9 [4.75] vs. posthemoadsorption SOFA score 7.7 [5.4], p = 0.046) were observed. ICU and in-hospital mortality was 33.7%.Conclusions: In this case series, critically ill patients with COVID-19 with severe acute respiratory failure refractory to prone positioning and hypercytokinemia who received adjuvant treatment with cytokine hemoadsorption showed a significant reduction in IL-6 plasma levels and other inflammatory biomarkers. Improvements in oxygenation and SOFA score were also observed.
Relief After COVID-19 Vaccination: A Doubtful or Evident Outcome?
Authors: Al-Hanawi Mohammed Khaled , Alshareef Noor , El-Sokkary Rehab H. 
Published: January 2022

Background:Since development of the first COVID-19 vaccine, the landscape of public confidence in these vaccines is uncertain. Building confidence is crucial for better preparedness of future pandemics. Following the mandatory COVID-19 vaccination policy in the country, the aim of this study was to examine whether the Saudi public feels relieved post-vaccination and to identify the factors predicting such relief.Methods:An online cross-sectional survey was conducted in July 2021 among COVID-19 vaccine recipients in Saudi Arabia. A multivariable logistic regression analysis was employed to examine and identify the variables associated with feeling relieved post-vaccination.Results:Most of the respondents (66%) stated feeling more relieved post-vaccination. Male gender [adjusted odds ratio (AOR): 1.380; 95% confidence interval (CI): 0.981–1.943], being a student (AOR: 3.902; 95% CI: 1.674–9.096), and received two doses of the vaccine (AOR: 2.278; 95% CI: 1.630–3.182) were associated with feeling more relieved after getting vaccinated. Respondents who were anxious about the vaccine before receiving it (AOR: 0.220; 95% CI: 0.160–0.302), and experienced a severe reaction after vaccination (AOR: 0.288; 95% CI: 0.165–0.504) had lower odds of feeling relieved post-vaccination. Respondents who relied on social media as the main source of vaccine-related information and those having no information about the vaccine were also less likely to feel relieved post-vaccination.Conclusions:Individuals' attitudes toward COVID-19 vaccines may not necessarily alter post-vaccination. Although mandatory vaccination policies can significantly contribute to achieving herd immunity, public confidence toward vaccines might be eroded, which could in turn impose significant challenges in future pandemics efforts.