bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trajectory Tracking Robot Omnidirectional 4 Roda Dengan Visualisasi Rviz
Authors: Fadhila Ivan , Siradjuddin Indrazno , Putri Ratna Ika 
Published: August 2022

Pada proses industri, robot difungsikan untuk menyelesaikan permasalahan industri salah satunya memindahkan barang ke tempat yang sudah ditentukan. Oleh sebab itu, dikembangkan sebuah robot yang dapat bergerak ke segala arah dalam bidang kartesian x-y tanpa perlu haluan saat arah hadap berubah, salah satunya adalah robot omnidirectional atau biasa disebut robot holonomic. Pergerakan robot terkontrol akan membuat robot dapat menuju posisi yang diinginkan secara akurat dan benar, sehingga dibutuhkan sebuah kontrol kinematik yang dapat mengatur pergerakan robot. Dengan menggunakan kontrol kinematik, pergerakan robot dapat dikontrol dengan cara menentukan kecepatan putar masing masing robot. Tracking dan Navigasi bertujuan untuk memantau dan mengontrol posisi robot agar menghindari menabrak object dan kondisi tidak aman lainnya tanpa perlu mendekat, yaitu dengan cara memonitoring melalui visualisasi menggunakan Rviz. Pada mobile robot ini akan menstabilkan gerak navigasi robot sesuai dengan setpoint yang diinginkan. Setelah dilakukan pengujian ditemukan nilai faktor penguat error ( ) = 25, dan Berdasarkan hasil robot mampu meninggkatkan kemampuan robot untuk bergerak cepat pada lapangan.
Alat Pengukur Sudut Aman Pada Z Bar 3D Printing Dengan Metode Tolerated Zero Angle
Authors: Arumdhani Rahma Aprilia , Setiawan Budhy , Pracoyo Agus 
Published: August 2022

— Seiring berjalannya waktu, kemajuan pada bidang teknologi juga berkembang pesat. Banyak permasalahan yang dapat diselesaikan dengan teknologi salah satu contohnya adalah mesin 3D Printer yang mampu mencetak berbagai jenis prototype. Terdapat berbagai jenis dan ukuran 3D printer, semakin besar ukuran 3D printer maka 3D printer bisa mencetak prototype dengan ukuran yang lebih besar pula. Pergerakkan dari sumbu X dan Y digerakkan oleh bed plate levelling sedangkan pergerakkan sumbu Z dibantu dengan 2 motor untuk membuat gerakkan ke atas dan ke bawah. Untuk sumbu Z dibutuhkan sinkronisasi antara satu motor dengan motor yang lainnya. Jika pergerakan antara 2 motor sumbu Z ini tidak sama, maka akan berakibat Z bar bengkok/patah, tentunya hal merupakan kesalahan yang fatal dan dapat mengganggu kinerja dari 3D Printer tersebut. Maka dari itu, diperlukan alat sistem keamanan yang berfungsi untuk mencegah terjadinya Z bar miring. Dengan menggunakan sensor accelerometer yang digunakan untuk menghitung sudut pitch, maka kita dapat mengetahui perubahan sudut kemiringan yang ada pada Z bar . Hasil dari pembacaan sensor kemudian akan di bandingkan dengan setpoint yang telah ditentukan, selanjutnya jika hasil pembacaan sensor melebihi setpoint maka sistem akan memutus arus supply mesin 3D Printing yang artinya sistem keamanan aktif.
Implementasi Metode PID untuk Pengendalian Motor AC pada Crusher Daun Kelor
Authors: Ramadhani Riezky Delthone , Priyadi Bambang , Subiyantoro Subiyantoro 
Published: August 2022

Intisari — Kelor merupakan tanaman herbal yang bermanfaat bagi kesehatan. Cara konsumsinya kebanyakan dengan diseduh setelah sebelumnya daun kelor dikeringkan dan diolah menjadi serbuk. Penelitian ini dilakukan untuk meningkatkan efektivitas crusher daun kelor menjadi serbuk dengan mengaplikasikan teknologi elektronika. Motor AC satu fasa menjadi crusher daun kelor dengan memanfaatkan sistem kontrol Proportional Integral Derivatif (PID) untuk memperoleh kecepatan motor yang stabil dan dapat diatur. Sensor kecepatan rotary encoder menjadi sumber data kecepatan motor dengan umpan balik menuju mikrokontroler Arduino Uno. Arduino akan menghasilkan sinyal PWM yang mengendalikan driver motor untuk pengaturan kecepatan motor. Driver motor ini terdiri dari rangkaian dimmer AC dengan komponen utama Triac, Diac, kapasitor, dan potensiometer. Motor servo digunakan pula untuk pengendalian mekanik potensiometer sehingga menghasilkan daya keluaran rangkaian dimmer AC yang dapat dikendalikan sebagai catu daya motor AC satu fasa. Hasil penelitian menunjukan bahwa parameter kontrol paling ideal bernilai Kp=1.28, Ki=0.25, dan Kd=3.15. Respon sistem kontrol PID pada setpoint kecepatan 1400 Rpm menghasilkan nilai Ts=13 detik, Os=6.4%, Tr=5 detik, dan Td=2 detik.Kata Kunci –Dimmer AC, Motor AC, PID, Rotary Encoder
Multiple Pickering emulsions stabilized by the same particles with different extent of hydrophobization in situ
Authors: Zhu Yue , Chen Tingting , Cui Zhenggang 
Published: August 2022

Multiple emulsions are widely used in pharmaceuticals, foods, and cosmetics. However, those stabilized by surfactants with different HLB values are generally unstable due to the diffusion of the surfactants between inner and outer interfaces. Here, we report that multiple W/O/W emulsions can be prepared by using the same particles in combination with a surfactant of different concentrations. The less surface-active raw CaCO3 nanoparticles can be hydrophobized to surface-active in situ by adsorption of the anionic surfactant SDS, and the wettability of the particles can be controlled to be suitable for stabilizing both O/W and W/O Pickering emulsions by adjusting the surfactant concentration. With toluene as oil phase, the CaCO3 particles at 1.0 wt% tend to stabilize a W/O emulsion in the presence of 3 mm SDS in an aqueous solution, which can then be further dispersed in an aqueous phase with 1.0 wt% CaCO3 and SDS below 1 mm to form a W/O/W multiple emulsion. The effects of the ratio of W/O emulsion to the outer water phase and the preparation methods on stabilization of multiple emulsions were examined. With a ratio smaller than 3:1 and by gentle magnetic stirring, the multiple emulsions obtained can stay stable for at least a month without coalescence. This simple method not only ensures stabilization of multiple emulsions but also avoids complicated synthesis of colloid particles with different wettability.
Synthesis and antibacterial activity evaluation of N (7) position-modified balofloxacins
Authors: Hong Ge , Li Weitian , Mao Lina , Wang Jiawen , Liu Tianjun 
Published: August 2022

A series of small-molecule fluoroquinolones were synthesized, characterized by HRMS and NMR spectroscopy, and screened for their antibacterial activity against MRSA, P. aeruginosa, and E. coli as model G+/G− pathogens. Compounds 2-e, 3-e, and 4-e were more potent than the reference drug balofloxacin against MRSA and P. aeruginosa (MIC values of 0.0195 and 0.039 μg/ml for 2-e, 0.039 and 0.078 μg/ml for each of 3-e and 4-e, respectively). Analysis of the time-dependent antibacterial effect of compound 2-e toward MRSA showed that in the early logarithmic growth phase, bactericidal effects occurred, while in the late logarithmic growth phase, bacterial inhibition occurred because of concentration effects and possibly the development of drug resistance. Compound 2-e exhibited low toxicity toward normal mammalian cell lines 3T3 and L-02 and tumor cell lines A549, H520, BEL-7402, and MCF-7. The compound was not hemolytic. Atomic force microscopy (AFM) revealed that compound 2-e could effectively destroy the membrane and wall of MRSA cells, resulting in the outflow of the cellular contents. Docking studies indicated the good binding profile of these compounds toward DNA gyrase and topoisomerase IV. ADMET’s prediction showed that most of the synthesized compounds followed Lipinski’s “rule of five” and possessed good drug-like properties. Our data suggested that compound 2-e exhibited potent anti-MRSA activity and is worthy of further investigation.
Right ventricular-pulmonary arterial coupling impairment and exercise capacity in obese adults
Authors: Zhou Na , Forton Kevin , Motoji Yoshiki , Scoubeau Corentin , Klass Malgorzata , Naeije Robert , Faoro Vitalie 
Published: August 2022

BackgroundObesity-related exercise intolerance may be associated with pulmonary vascular and right ventricular dysfunction. This study tested the hypothesis that decreased pulmonary vascular reserve and right ventricular (RV)-pulmonary arterial (PA) uncoupling contributes to exercise limitation in subjects with obesity.MethodsSeventeen subjects with obesity were matched to normo-weighted healthy controls. All subjects underwent; exercise echocardiography, lung diffusing capacity (DL) for nitric oxide (NO) and carbon monoxide (CO) and an incremental cardiopulmonary exercise test. Cardiac output (Q), PA pressure (PAP) and tricuspid annular plane systolic excursion (TAPSE) were recorded at increasing exercise intensities. Pulmonary vascular reserve was assessed by multipoint mean PAP (mPAP)/Q relationships with more reserve defined by lesser increase in mPAP at increased Q, and RV-PA coupling was assessed by the TAPSE/systolic PAP (sPAP) ratio.ResultsAt rest, subjects with obesity displayed lower TAPSE/sPAP ratios (1.00 ± 0.26 vs. 1.19 ± 0.22 ml/mmHg, P &lt; 0.05), DLCO and pulmonary capillary blood volume (52 ± 11 vs. 64 ± 13 ml, P &lt; 0.01) compared to controls. Exercise was associated with steeper mPAP-Q slopes, decreased TAPSE/sPAP and lower peak O2 uptake (VO2peak). The changes in TAPSE/sPAP at exercise were correlated to the body fat mass (R = 0.39, P = 0.01) and VO2peak (R = 0.44, P &lt; 0.01).ConclusionObesity is associated with a decreased pulmonary vascular and RV-PA coupling reserve which may impair exercise capacity.
Lower body mass index potentiates the association between skipping breakfast and prevalence of proteinuria
Authors: Muratsu Jun , Kamide Kei , Fujimoto Takashi , Takeya Yasushi , Sugimoto Ken , Taniyama Yoshiaki , Morishima Atsuyuki , Sakaguchi Katsuhiko , Rakugi Hiromi 
Published: August 2022

BackgroundProteinuria is an important predictor of cardiovascular disease and mortality. Several studies reported the association between skipping breakfast and the prevalence of proteinuria. Furthermore, skipping breakfast was associated with an increased risk of obesity. Although proteinuria is highly prevalent in obese individuals, the association between the prevalence of proteinuria and low body mass index (BMI) was reported in a previous cross-sectional study in asymptomatic individuals without known kidney diseases. The aim of this cross-sectional study was to assess the clinical impact of BMI on the association between skipping breakfast and the prevalence of proteinuria in normal renal function subjects.MethodsThe present study included 26,888 subjects (15,875 males and 11,013 females) with an estimated glomerular filtration rate ≥60 ml/min/1.73 m2 and no history of kidney disease who underwent a health checkup in Sumitomo Hospital. The association between skipping breakfast and the prevalence of proteinuria (defined as dipstick proteinuria of ≥1+) was assessed using logistic regression models adjusted for clinically relevant factors.ResultsSkipping breakfast was reported in 3,306 males (20.8%) and 1,514 females (13.8%). Multivariable adjusted logistic regression models showed that skipping breakfast was significantly associated with the prevalence of proteinuria above 1+. This association was evident in lower BMI subjects, even after adjusting for clinically relevant factors (adjusted odds ratios of males and females were 1.67 [1.17–2.38] and 1.92 [1.31–2.82], respectively), whereas this association was not evident in higher BMI subjects.ConclusionLower BMI subjects with proteinuria might need to be careful about skipping breakfast.
Techno-economic analysis of a PV system with a battery energy storage system for small households: A case study in Rwanda
Authors: Nkuriyingoma Obed , Özdemir Engin , Sezen Serkan 
Published: August 2022

Due to the inadequacy of distribution networks in developing countries, especially in small residential areas, there are frequent interruptions in the electrical energy provided by the grid. This problem negatively affects the life quality and productivity of the people living in these regions. This problem can be overcome by integrating BESS-supported renewable energy sources into the distribution system. These distributed energy resources contribute significantly to providing energy directly to consumers. On a small scale, such a system is supported by the grid, when possible, to ensure energy supply continuity. This study presents a techno-economic analysis, using PV*SOL simulation software, of a grid-connected solar PV system with BESS that is used to supply a small residential community in Rwanda, Muhanga district, Shyogwe sector. The consumers were a group of one hundred households around a wetland valley. The energy generated from the solar PV system was used to supply home appliances and a water pumping system for agricultural activities. The simulation results showed that the annual energy requirement is 82.34 MWh with a peak load of 30.4 kW. The simulation results also revealed that a PV system, with an installed capacity of 57.33 kWp integrated with a BESS of 89.2 kWh storage capacity, can supply the load with own power consumption of 68.65%, a level of self-sufficiency of 64.38%, and a performance ratio of 86.05% when the desired ratio is set to 110% with a year as the reference period. The financial analysis demonstrated a return on assets of 9.14% and an amortization period of 9.65 years. These results indicate that the proposed method is technically and economically feasible for use in addressing the issue of electrical power outages in developing countries.
Human Impact Scale on the Preservation of Archaeological Sites from Mostiştea Valley (Romania)
Authors: Covătaru Cristina , Stal Cornelis , Florea Mihai , Opriș Ionela , Simion Corina , Rădulescu Ileana , Călin Romeo , Ignat Theodor , Ghiță Cristina , Lazăr Cătălin 
Published: August 2022

Through time, both natural and cultural heritage have unfortunately been under threat due to multiple environmental and human-induced factors, which are likely to trigger various hazards such as soil erosion, landslides, or land collapse. The analysis of old cartographic material, aerial imagery, and satellite imagery has been used in multiple studies to observe and understand the changes that archaeological sites have undergone over the last centuries. These efforts are intended, among other things, to raise awareness of the threats affecting cultural heritage and prevent damages and preserve tangible evidence of the distant past. In this study, historical maps and satellite imagery were analyzed to observe how the landscape in the Mostiștea Valley (Romania) has been used over the last 230 years and how the land use has affected the cultural heritage. Land cover and land use (LCLU) changes in the Mostiștea Valley have occurred due to numerous natural and anthropic forces. These changes have resulted in the damage of tangible heritage in the area with varying degrees of intensity. The results of this study allow the quantification of the magnitude of these changes and their impact on different sites in the region.
Genetic evaluation of Jatropha backcross hybrid clones (BC4F1) for yield and oil quality
Authors: Jawahar Vishnu M. V. , Parthiban K. T. , Umadevi M. , Sudhagar R. Jude , Fernandaz C. Cinthia , Javed Talha , Kumar Uttam , Alotaibi Saqer S. 
Published: August 2022

Jatropha curcas is a tropical species that has been recognized as a promising biodiesel plant. During 2018–2021, researchers at Forest College and Research Institute, Mettupalayam, elicited information on Jatropha’s biochemical characteristics, growth performance, variability, and association studies for biometric variables using five backcross (BC4F1) hybrid clones of Jatropha with a control variety TNMC 7. In terms of seed yield, two hybrid clones, CJH 13 (1,218.60 g) and CJH 12 (1,034.40 g), outperformed the other hybrid clones. The seed oil content was higher in CJH 5 (34.19%). The seed oil content had moderate PCV (16.49%) and GCV (16.39%) values, as well as high heritability (99%) and genetic advance (33.56%) as a percentage of the mean. The number of fruits per bunch (0.845 and 0.850) and the number of bunches per branch (0.771 and 0.788) had significant positive phenotypic and genotypic correlations with seed yield, respectively. The iodine numbers, cetane numbers, and saponification values of all hybrid clones were acceptable and satisfactory and were in good compliance with Indian and international biodiesel standards.
Existence of viable Mycobacterium leprae in natural environment and its genetic profiling in a leprosy endemic region
Authors: Turankar Ravindra P. , Singh Vikram , Lavania Mallika , Singh Itu , Sengupta Utpal , Jadhav Rupendra S. 
Published: August 2022

IntroductionMolecular epidemiology of leprosy is very important to study leprosy transmission dynamics and to enhance our understanding of leprosy in endemic areas by utilizing the molecular typing method. Nowadays our understanding of leprosy transmission dynamics has been refined by SNP typing and VNTR marker analysis of M. leprae strains.ObjectiveThis study was carried out to find out the presence of viable M. leprae in the soil and water samples from residing areas of leprosy patients staying in different blocks of Purulia district of West Bengal, understanding their genotypes and compared with that of M. leprae present in patients.Material and methodsSlit-skin smear (SSS) samples (n=112) were collected from the active multibacillary leprosy patients from different blocks of leprosy endemic area. Soil samples (n=1060) and water samples (n=620) were collected from residing areas of leprosy patients. SNP subtyping was performed by PCR followed by sequencing. Multiplex PCR was performed using fifteen ML-VNTR loci and results were analysed.ResultsWe observed high PCR positivity in soil samples (344 out of 1060; 32%) and water samples (140 out of 620; 23%). These PCR positive samples when further screened for viability, it was observed that 150 soil samples (44%) and 56 water samples (40%) showed presence of 16S rRNA. SNP typing of M. leprae revealed presence of predominantly type 1. SNP subtype 1D (83%) was most prevalent in all the blocks of Purulia followed by subtype 1C (15%) and subtype 1A (2%). SNP subtype 2F was noted in only one sample. SNP and VNTR combination showed presence of similar strain type in certain pockets of Purulia region which was responsible for transmission.ConclusionPresence of viable M. leprae in the environment, and presence of SNP Type 1 M. leprae in patients and environment suggests both environment and patients play a role in disease transmission.
Enlarged perivascular spaces are linked to freezing of gait in Parkinson's disease
Authors: Lin Fangju , Yang Baoling , Chen Ying , Zhao Wei , Li Binghan , Jia Weihua 
Published: August 2022

ObjectiveFreezing of gait (FOG) is one of common and disabling gait impairments of Parkinson's disease (PD). White matter hyperintensity (WMH) and lacunes, as common manifestations of cerebral small vessel diseases (CSVD), have been reported to be associated with gait function in PD patients. However, in the cases with FOG which present with extensive WMH or lacunes, it actually is difficult to distinguish pure PD pathology from vascular origin or combined effects. So far little is known about the correlation between enlarged perivascular space (PVS) and FOG in PD patients. This study aims to explore the role of enlarged PVS in FOG in PD patients.MethodsA total of 95 patients with PD in the absence of obvious WMH and lacunes were included in our study, which were divided into PD-FOG (+) group and PD-FOG (-) group. Demographic and clinical data were investigated. Enlarged PVS in the centrum semiovale (CSO) and basal ganglia (BG) were assessed. The association between enlarged PVS and FOG in patients with PD was analyzed using the multivariate models and the Spearman's correlation.ResultsThere were 36 PD patients grouped into PD-FOG (+) (37.9%), with an older age, a longer PD disease duration, and larger numbers of enlarged PVS in CSO and BG compared with PD-FOG (-) group. The highest-severity degree of enlarged PVS burden in CSO was independently associated with FOG in patients with PD [adjusted odds ratio (OR), 3.869; p = 0.022 in multivariable model]. The percentages of FOG case increased accompanied by the aggravation of enlarged PVS located in CSO. The grade and count of enlarged PVS in CSO and BG both correlated with FOGQ score in PD patients.ConclusionEnlarged PVS, particularly in CSO, are associated with FOG in patients with PD, which provides a novel perspective for the mechanisms of FOG in PD.
The effect of race/ethnicity on cancer-specific mortality after salvage radical prostatectomy
Authors: Wenzel Mike , Würnschimmel Christoph , Nocera Luigi , Colla Ruvolo Claudia , Hoeh Benedikt , Tian Zhe , Shariat Shahrokh F. , Saad Fred , Briganti Alberto , Graefen Markus , Preisser Felix , Becker Andreas , Mandel Philipp , Chun Felix K. H. , Karakiewicz Pierre I. 
Published: August 2022

BackgroundTo test the effect of race/ethnicity on cancer-specific mortality (CSM) after salvage radical prostatectomy (SRP).Material and methodsWe relied on the Surveillance, Epidemiology and End Results database (SEER, 2004–2016) to identify SRP patients of all race/ethnicity background. Univariate and multivariate Cox regression models addressed CSM according to race/ethnicity.ResultsOf 426 assessable SRP patients, Caucasians accounted for 299 (69.9%) vs. 68 (15.9%) African-Americans vs. 39 (9.1%) Hispanics vs. 20 (4.7%) Asians. At diagnosis, African-Americans (64 years) were younger than Caucasians (66 years), but not younger than Hispanics (66 years) and Asians (67 years). PSA at diagnosis was significantly higher in African-Americans (13.2 ng/ml), Hispanics (13.0 ng/ml), and Asians (12.2 ng/ml) than in Caucasians (7.8 ng/ml, p = 0.01). Moreover, the distribution of African-Americans (10.3%–36.6%) and Hispanics (0%–15.8%) varied according to SEER region. The 10-year CSM was 46.5% in African-Americans vs. 22.4% in Caucasians vs. 15.4% in Hispanics vs. 15.0% in Asians. After multivariate adjustment (for age, clinical T stage, lymph node dissection status), African-American race/ethnicity was an independent predictor of higher CSM (HR: 2.2, p &lt; 0.01), but not Hispanic or Asian race/ethnicity. The independent effect of African-American race/ethnicity did not persist after further adjustment for PSA.ConclusionAfrican-Americans treated with SRP are at higher risk of CSM than other racial/ethnic groups and also exhibited the highest baseline PSA. The independent effect of African-American race/ethnicity on higher CSM no longer applies after PSA adjustment since higher PSA represents a distinguishing feature in African-American patients.