bluuebunny/crossref_metadata_2025_split huggingface dataset:
Statistical and Dynamical Characteristics of Extreme Wave Crests Assessed with Field Measurements from the North Sea
Authors: Malila Mika P. , Barbariol Francesco , Benetazzo Alvise , Breivik Øyvind , Magnusson Anne Karin , Thomson Jim , Ward Brian 
Published: October 2022

Abstract
Wave crests of unexpected height and steepness pose a danger to activities at sea, and long-term field measurements provide important clues for understanding the environmental conditions that are conducive to their generation and behavior. We present a novel dataset of high-frequency laser altimeter measurements of the sea surface elevation gathered over a period of 18 years from 2003 to 2020 on an offshore platform in the central North Sea. Our analysis of crest height distributions in the dataset shows that mature, high sea states with high spectral steepness and narrow directional spreading exhibit crest height statistics that significantly deviate from standard second-order models. Conversely, crest heights in developing sea states with similarly high steepness but wide directional spread correspond well to second-order theory adjusted for broad frequency bandwidth. The long-term point time series measurements are complemented with space–time stereo video observations from the same location, collected during five separate storm events during the 2019/20 winter season. An examination of the crest dynamics of the space–time extreme wave crests in the stereo video dataset reveals that the crest speeds exhibit a slowdown localized around the moment of maximum crest elevation, in line with prevailing theory on nonlinear wave group dynamics. Extending on previously published observations focused on breaking crests, our results are consistent for both breaking and nonbreaking extreme crests. We show that wave crest steepness estimated from time series using the linear dispersion relation may overestimate the geometrically measured crest steepness by up to 25% if the crest speed slowdown is not taken into account.

Significance Statement
Better understanding of the statistics and dynamical behavior of extreme ocean surface wave crests is crucial for improving the safety of various operations at sea. Our study provides new, long-term field evidence of the combined effects of wave field steepness and directionality on the statistical distributions of crest heights in storm conditions. Moreover, we show that the dynamical characteristics of extreme wave crests are well described by recently identified nonlinear wave group dynamics. This finding has implications, for example, for wave force calculations and the treatment of wave breaking in numerical wave models.
A Review of Human Performance Models for Prediction of Driver Behavior and Interactions With In-Vehicle Technology
Authors: Park Junho , Zahabi Maryam 
Published: October 2022

Objective This study investigated the use of human performance modeling (HPM) approach for prediction of driver behavior and interactions with in-vehicle technology. Background HPM has been applied in numerous human factors domains such as surface transportation as it can quantify and predict human performance; however, there has been no integrated literature review for predicting driver behavior and interactions with in-vehicle technology in terms of the characteristics of methods used and variables explored. Method A systematic literature review was conducted using Compendex, Web of Science, and Google Scholar. As a result, 100 studies met the inclusion criteria and were reviewed by the authors. Model characteristics and variables were summarized to identify the research gaps and to provide a lookup table to select an appropriate method. Results The findings provided information on how to select an appropriate HPM based on a combination of independent and dependent variables. The review also summarized the characteristics, limitations, applications, modeling tools, and theoretical bases of the major HPMs. Conclusion The study provided a summary of state-of-the-art on the use of HPM to model driver behavior and use of in-vehicle technology. We provided a table that can assist researchers to find an appropriate modeling approach based on the study independent and dependent variables. Application The findings of this study can facilitate the use of HPM in surface transportation and reduce the learning time for researchers especially those with limited modeling background.
School and Home Contributions to Dietary Behaviors of Rural Youth
Authors: Lorenz Kent A. , Stylianou Michalis , Kulinna Pamela Hodges , Yu Hyeonho 
Published: October 2022

Purpose This study examined dietary behaviors of rural youth at school and at home and sociodemographic differences. Design A cross-sectional design was used. Setting The study took place in five rural schools in the Southwestern US. Sample Student participants (N = 751) were in 3rd-8th grades. Measures Consumption of fruits, vegetables, dairy, and soda/pop, at school and at home, were measured using a modified 7-day recall Youth Risk Behavior survey for nutrition instrument (CDC, 2011); Sociodemographic data. Analysis Descriptive statistics, frequency tables and MANCOVA were used. Results Following a natural log transformation of the dependent variables, there were significant multivariate effects in dietary behaviors across schools (Wilks’ λ = 0.962, F(16, 2539.4) = 2.05, P = 0.0082) and location (school v. home; Wilks’ λ = 0.849, F(4, 831) = 36.94, P < 0.0001). Follow-up tests showed students in some schools reported higher consumption of fruit, vegetable, and soda at home than school, although most reported consuming less than one serving per day of fruit, vegetables, and dairy across settings. There were no significant main effects for gender/grade/ethnicity across behaviors. Conclusions Findings highlight poor dietary behaviors of rural youth as well as school/home differences that can help inform efforts to support optimal dietary behaviors of this population. Results should be interpreted considering limitations of the self-report nature of collected data and missing data.
The Foot and Ankle Kinematics of a Simulated Progressive Collapsing Foot Deformity During Stance Phase: A Cadaveric Study
Authors: Henry Jensen K. , Hoffman Jeffrey , Kim Jaeyoung , Steineman Brett , Sturnick Daniel , Demetracopoulos Constantine , Deland Jonathan , Ellis Scott 
Published: October 2022

Background: Progressive collapsing foot deformity (PCFD) is a complex pathology associated with tendon insufficiency, ligamentous failure, joint malalignment, and aberrant plantar force distribution. Existing knowledge of PCFD consists of static measurements, which provide information about structure but little about foot and ankle kinematics during gait. A model of PCFD was simulated in cadavers (sPCFD) to quantify the difference in joint kinematics and plantar pressure between the intact and sPCFD conditions during simulated stance phase of gait. Methods: In 12 cadaveric foot and ankle specimens, the sPCFD condition was created via sectioning of the spring ligament and the medial talonavicular joint capsule followed by cyclic axial compression. Specimens were then analyzed in intact and sPCFD conditions via a robotic gait simulator, using actuators to control the extrinsic tendons and a rotating force plate underneath the specimen to mimic the stance phase of walking. Force plate position and muscle forces were optimized using a fuzzy logic iterative process to converge and simulate in vivo ground reaction forces. An 8-camera motion capture system recorded the positions of markers fixed to bones, which were then used to calculate joint kinematics, and a plantar pressure mat collected pressure distribution data. Joint kinematics and plantar pressures were compared between intact and sPCFD conditions. Results: The sPCFD condition increased subtalar eversion in early, mid-, and late stance ( P < .05), increased talonavicular abduction in mid- and late stance ( P < .05), and increased ankle plantarflexion ( P < .05), adduction ( P < .05), and inversion ( P < .05). The center of plantar pressure was significantly ( P < .01) medialized in this model of sPCFD and simulated stance phase of gait. Discussion: Subtalar and talonavicular joint kinematics and plantar pressure distribution significantly changed with the sPCFD and in the directions expected from a PCFD foot. We also found that ankle joint kinematics changed with medial and plantar drift of the talar head, indicating abnormal talar rotation. Although comparison to an in vivo PCFD foot was not performed, this sPCFD model produced changes in foot kinematics and indicates that concomitant abnormal changes may occur at the ankle joint with PCFD. Clinical Relevance: This study describes the dynamic kinematic and plantar pressure changes in a cadaveric model of simulated progressive collapsing foot deformity during simulated stance phase.
COVID-19 Pandemic: The Local Community Perceptions and Associated Risks in Guji Society, Southern Ethiopia
Authors: Roba Gemeda Odo 
Published: October 2022

Objective To investigate local perceptions of the causes and prevention of the COVID-19 pandemic in Guji Society, West Guji Zone, Bule Hora district. Methods The researcher conducted a qualitative study using in-depth interviews and key informant interviews, focus group discussions, and case study with 46 informants, of which 22 were women and 24 were men. The informants were recruited using purposive sampling. The data was analyzed by qualitative description. Results The findings indicate the wrath of Waaqaa (God), evil spirit attacks, Gadaa party's omen, the virus, and unknown forces are thought to be the causes of the virus. The local amelioration and prevention mechanisms reported by the informants were rituals of praying for God's mercy and social distancing, along with using face-masks, keeping hygiene, and getting vaccines. Conclusion The local community's perceptions about the COVID-19 pandemic's causes and prevention methods are based on myths, assumptions, and belief systems that contradict medical science concepts and prevention methods. As a result, this scenario would result in potential risk factors like susceptibility to the virus, severe health complications, and psychological and socio-economic adverse impacts.
Nursing Care Delivery Models and Intraprofessional Collaborative Care: Canadian Nurse Leaders’ Perspectives
Authors: Prentice Dawn , Moore Jane , Fernandes Bruna , Larabie Emma 
Published: October 2022

Introduction There are many different types of nursing care delivery models used to organize and provide care in hospitals. These models are comprised of different organizational structures and staffing skill mixes. Objective The aim of this study was to explore how nursing care delivery models promote intraprofessional collaborative care in acute care hospitals from the perspectives of nurse leaders. Methods A qualitative descriptive approach was used for this study. Telephone interviews were conducted between January 2021 and August 2021 using an interview guide comprised of semi-structured and structured questions. Using a purposeful sampling technique, ten leaders from nine hospital systems, representing both urban and rural hospitals in the province of Ontario, Canada, participated in the study. Content analysis was conducted resulting in two overarching themes. Results The first theme, Fluidity of the Model addresses the flexibility of the models and the impact of contextual factors such as changes in nurses’ scope of practice, government funding changes, staffing mix, and organizational policies and rules. The second theme, Tools of the Trade describes the resources that hospitals implement to promote intraprofessional collaboration that indirectly impacts on patient safety. Conclusion Nursing care delivery models need to be flexible and adaptable. All nursing care delivery models in this study used various tools to promote intraprofessional collaborative care.
Toxicity and efficacy of CAR T-cell therapy in primary and secondary CNS lymphoma: a meta-analysis of 128 patients
Authors: Cook Michael R. , Dorris C. Scott , Makambi Kepher H. , Luo Yutong , Munshi Pashna N. , Donato Michelle , Rowley Scott , Saad Ayman , Goy Andre , Dunleavy Kieron , Ali Alaa 
Published: October 2022

Abstract
Relapsed/refractory primary central nervous system lymphoma (PCNSL) and secondary central nervous system lymphoma (SCNSL) are associated with short survival and represent an unmet need, requiring novel effective strategies. Anti-CD19 chimeric antigen receptor (CAR) T cells, effective in systemic large B-cell lymphoma (LBCL), have shown responses in PCNSL and SCNSL in early reports, but with limited sample size. We, therefore, performed a comprehensive systematic review and meta-analysis of all published data describing CAR T-cell use in PCNSL and SCNSL. This identified 128 patients with PCNSL (30) and SCNSL (98). Our primary objectives were to evaluate CAR T-cell specific toxicity (immune effector cell-associated neurotoxicity syndrome [ICANS] and cytokine release syndrome [CRS]) as well as response rates in these 2 populations. Seventy percent of patients with PCNSL had CRS of any grade (13% grade 3-4) and 53% had ICANS of any grade (18% grade 3-4). Comparatively, 72% of the SCNSL cohort experienced CRS of any grade (11% grade 3-4) and 48% had ICANS of any grade (26% grade 3-4). Of the patients with PCNSL, 56% achieved a complete remission (CR) with 37% remaining in remission at 6 months. Similarly, 47% of patients with SCNSL had a CR, with 37% in remission at 6 months. In a large meta-analysis of central nervous system (CNS) lymphomas, toxicity of anti-CD19–CAR T-cell therapy was similar to that of registrational studies in systemic LBCL with no increased signal of neurotoxicity observed. Encouraging efficacy was demonstrated in patients with CNS lymphoma with no discernible differences between PCNSL and SCNSL.
Effect of integration of poultry manure and vinasse on the abundance and diversity of soil fauna, soil fertility index, and barley (Hordeum aestivum L.) growth in calcareous soils
Authors: Seleem Mostafa , Khalafallah Naglaa , Zuhair Raghda , Ghoneim Adel M. , El-Sharkawy Mahmoud , Mahmoud Esawy 
Published: October 2022

AbstractBackground:In Egypt, calcareous soils represent a large part of desert soils suffering from a shortage of nutrients and organic matter, affecting production and biological diversity in agroecosystems. Organic wastes, negatively affect the environment, recycling it as a promising technology in different farming systems, and its impact on crop productivity and soil fauna is largely unknown. In this study, the effects of integrating poultry manure (PM) alone or combined with vinasse (V) at rates of 4.2 g kg− 1and 6.3 g kg− 1in pots, on improving soil fauna diversity, soil fertility, soil consistency and yield of barley (Hordeum aestivumL.) grown in a calcareous soil were investigated.Results:The results showed that the addition of PM alone or combined with V at different rates led to a significant increase in the microbial biomass carbon (MBC), organic matter (OM), NPK soil availability and yield of barley. The addition of 6.3 g PM and 4.2 g V kg− 1soil have the best results in OM with 65.0% compared to control, and V contributes more than 16% of them. Prostigmata and Collembola were the dominant groups and accounted for 43.3% and 50.0% in the PM1 and 50.0% and 20.0% in the PM2 of the total individuals, respectively. Shannon and Evenness indices increased significantly with the soil amended by PM alone or combined with V. Soil fauna plays a key role in soil consistency because of a significant relationship between soil fauna and soil OM, MBC and soil fertility index. The addition of 6.3 g PM and 4.2 g V kg− 1soil gave the best results in grain yield by 76.90% compared to the control.Conclusion:In conclusion, the interaction between PM and V can be used as a promising organic amendments to increase barley yield and improve efficiency of a recycled PM and V on soil fauna and soil fertility of calcareous soil.
Association between common laboratory indices and IgAV recurrence in children
Authors: Zhou Juan , Li Li , Luo Jing , Yang Yingtian , Shen Xing 
Published: October 2022

Abstract
Background
IgA vasculitis (IgAV) is a common type of vasculitis seen in children. IgAV recurrence can result in chronic kidney disease. We aimed to explore the association between common laboratory indices and IgAV recurrence in children, and to establish a prediction model.

Methods
This retrospective study included children with diagnosed with IgAV hospitalized in Bazhong Central Hospital, Sichuan, from January 2014 to December 2019. Children were assigned to two groups based on IgAV recurrence, and baseline clinical data were collected for comparison. A logistic regression model to predict IgAV recurrence was established. The receiver operating characteristic curve was plotted. The area under the curve (AUC) was used to detect performance of the predictive model.

Results
This study included 193 children (39 [20.2%], recurrence group; 154 [79.8%], non-recurrence group). Based on multivariate regression analysis, the duration of illness and joint involvement were independent predictors of IgAV recurrence in children (P < 0.05). No significant differences were observed in common laboratory indices (P > 0.05). The AUC of the prediction model was 0.766 (P < 0.001) with sensitivity of 74.4% and specificity of 68.8%.

Conclusion
Common laboratory indices were not associated with recurrence of IgAV in children.
Systematic review and meta-analysis of head-to-head trials comparing sulfonylureas and low hypoglycaemic risk antidiabetic drugs
Authors: Volke Vallo , Katus Urmeli , Johannson Annika , Toompere Karolin , Heinla Keiu , Rünkorg Kertu , Uusküla Anneli 
Published: October 2022

Abstract
Background
Safety of sulfonylurea drugs in the treatment of Type 2 Diabetes is still under debate. The aim of this study was to compare the all-cause mortality and cardiovascular adverse events of sulfonylureas and drugs with a low risk for hypoglycaemia in adults with type 2 diabetes.

Methods
Systematic review and meta-analysis of randomised controlled trials. Data sources: MEDLINE (PubMed, OVID), Embase, Cochrane Central Register of Controlled Trials, CINAHL, WOS and Lilacs.

Study selection
Randomised controlled head-to-head trials that compared sulfonylureas with active control with low hypoglycaemic potential in adults (≥ 18 years old) with type 2 diabetes published up to August 2015. The drug classes involved in the analysis were metformin, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose co-transporter-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists.

Outcomes
The primary endpoint was all-cause mortality. The secondary endpoints were MACE, cardiovascular events and severe hypoglycaemia. Synthesis of results: Two reviewers checked study eligibility, independently extracted data and assessed quality with disagreements resolved through discussion. We assessed the risk of bias of the included studies using the Cochrane risk of bias tool for randomized trials v2. Pooled odds ratios (ORs) were estimated by using fixed effects model. The study is registered on PROSPERO (26/05/2016 CRD42016038780).

Results
Our final analysis comprised 31 studies (26,204 patients, 11,711 patients given sulfonylureas and 14,493 given comparator drugs). In comparison to drugs with low hypoglycaemic potential, sulfonylureas had higher odds for all-cause mortality (OR 1.32, 95% CI 1.00-1.75), MACE (OR 1.32, 95% CI 1.07–1.61), myocardial infarction (fatal and non-fatal) (OR 1.67, 95% CI 1.17–2.38) and hypoglycaemia (OR 5.24, 95% CI 4.20–6.55). Subsequent sensitivity analysis revealed differences in the effect of sulfonylureas, with an increased risk of all-cause mortality with glipizide but not the other molecules.

Conclusion
Our meta-analysis raises concern about the safety of SUs compared to alternative drugs involved in current analysis. Important differences may exist within the drug class, and glimepiride seems to have best safety profile.
Efficacy and safety of curcuminoids alone in alleviating pain and dysfunction for knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Authors: Feng Jie , Li Zhao , Tian Linling , Mu Panyun , Hu Yimei , Xiong Feng , Ma Xu 
Published: October 2022

Abstract
Background
Curcuminoids (CURs) are the principal ingredients of Curcuma longa L. [Zingiberaceae] (CL)—an herbal plant used in east Asia to alleviate pain and inflammation. Thus far, the therapeutic effects of CURs for knee osteoarthritis (OA) uncovered by multiple reviews remained uncertain due to broadly involving trials with different agents-combined or CURs-free interventions. Therefore, we formed stringent selection criteria and assessment methods to summarize current evidence on the efficacy and safety of CURs alone in the treatment of knee OA.

Methods
A series of databases were searched for randomized controlled trials (RCTs) evaluating the efficacy and safety of CURs for knee OA. Clinical outcomes were evaluated using meta-analysis and the minimum clinically important difference (MCID) for both statistical and clinical significance.

Results
Fifteen studies with 1670 patients were included. CURs were significantly more effective than placebo in the improvements of VAS for pain ( WMD: − 1.77, 95% CI: − 2.44 to − 1.09), WOMAC total score ( WMD: − 7.06, 95% CI: − 12.27 to − 1.84), WOMAC pain score ( WMD: − 1.42, 95% CI: − 2.41 to − 0.43), WOMAC function score ( WMD: − 5.04, 95% CI: − 7.65 to − 2.43), and WOMAC stiffness score ( WMD: − 0.54, 95% CI: − 1.03 to − 0.05). Meanwhile, CURs were not inferior to NSAIDs in the improvements of pain- and function-related outcomes. Additionally, CURs did not significantly increase the incidence of adverse events (AEs) compared with placebo ( RR: 1.03, 95% CI: 0.69 to 1.53, P = 0.899, I2 = 23.7%) and NSAIDs (RR: 0.71 0.65, 95% CI: 0.57 0.41 to 0.90 1.03).

Conclusions
CURs alone can be expected to achieve considerable analgesic and functional promotion effects for patients with symptomatic knee OA in short term, without inducing an increase of adverse events. However, considering the low quality and substantial heterogeneity of present studies, a cautious and conservative recommendation for broader clinical use of CURs should still be made. Further high-quality studies are necessary to investigate the impact of different dosages, optimization techniques and administration approaches on long-term safety and efficacy of CURs, so as to strengthen clinical decision making for patients with symptomatic knee OA.