bluuebunny/crossref_metadata_2025_split huggingface dataset:
A randomized controlled trial of a coping-focused family resilience intervention program for breast cancer patients: Study protocol
Authors: Gao Jie , Li Jia-Xin , Chen Wei-Ying , Song Jiang-Yan , Zhou Meng-Ke , Zhang Shan-Shan , Li Hui-Ping 
Published: October 2022

BackgroundBreast cancer patients and their families are under various pressures in the process of disease diagnosis and treatment, which seriously threaten their physical and mental health. Findings from existing research suggest that good family resilience can help breast cancer families better adapt and cope with adversity and challenges. However, there are only a few intervention studies on family resilience and no intervention studies on resilience among the families of breast cancer patients. Therefore, this study aims to explore appropriate measures to improve the resilience level of breast cancer families and help them better cope with the disease.ObjectiveThe purpose of this study protocol is to demonstrate a coping-focused family resilience intervention to increase the level of resilience in the families of breast cancer patients and help them better cope with adversity.MethodsThe trial will recruit 80 breast cancer families and randomly assign them to experimental and control groups in a 1:1 ratio. The control group will receive routine care, and the intervention group will receive a 6-week one-on-one online family resilience intervention based on the control group. Two groups of subjects will be assessed at baseline and at 1 week, 1 month, and 3 months after the intervention. The primary outcome is family resilience, and the secondary outcomes are coping style, social support, family disease burden, and levels of anxiety and depression.Expected resultsWe hypothesized that after the intervention, the intervention group would have significantly higher levels of family resilience than the preintervention and control groups. In the intervention group, other aspects related to family resilience, such as family disease burden and anxiety and depression levels of patients and their families, were significantly alleviated, and disease coping and social support levels were improved accordingly.DiscussionIf the program works, it can help breast cancer families identify family strengths and resources to proactively address challenges so that families can successfully navigate the crisis and patient and family recovery can be facilitated. It can also provide a practical path for clinical workers to help breast cancer families adjust rationally.Clinical Trial RegistrationThis study has been registered in the Chinese Clinical Trials Registry (Registration Number: http://www.chictr.org.cn/ChiCTR2100052108).
Epidemiological characteristics and survival analysis on patients with occupational pneumoconiosis in Zhejiang Province from 1987 to 2019
Authors: Zou Hua , Shi Zhihao , Zhang Yixin , Zhou Jiena , Fang Xinglin , Zhang Yijin , Hu Yong , Lou Xiaoming , Zhou Lifang 
Published: October 2022

ObjectiveTo evaluate risk factors affecting survival in patients diagnosed with pneumoconiosis and propose strategies to improve the quality of life in these patients.MethodsThe basic patient information was obtained from the pneumoconiosis report card. Disease types, regions, and industry distribution of pneumoconiosis were analyzed. The Kaplan-Meier survival curves and the Cox proportional risk regression model was used for survival analysis.ResultsA total of 13,812 patients were diagnosed with pneumoconiosis in Zhejiang province from 1987 to 2019. The overall survival rate at the end of life table analysis was 83%. Kaplan-Meier analyses showed that there were significant differences between survival curves depending on the stage of first diagnosis, age at first diagnosis, type of pneumoconiosis, industry, and duration of dust exposure (P &lt; 0.05). The results of Cox proportional hazards regression analysis showed that pneumoconiosis stage of first diagnosis, age at first diagnosis, industry, and duration of dust exposure were risk factors affecting patient survival (P &lt; 0.05).ConclusionsThe patients with high stage of pneumoconiosis at first diagnosis, older age, and long duration of dust exposure should be followed up and monitored as key population, and the industries with high incidence of pneumoconiosis such as mining and construction should be supervised as key industries.
Blue sky as a protective factor for cardiovascular disease
Authors: Tang Haosu , Zheng Congyi , Cao Xue , Wang Su , Zhang Linfeng , Wang Xin , Chen Zuo , Song Yuxin , Chen Chen , Tian Yixin , Jiang Wenping , Huang Gang , Wang Zengwu 
Published: October 2022

ObjectiveBlue sky has been considered to boost outdoor physical activity and social interaction, ameliorate work pressure and life stress, and enhance people's sense of happiness. However, the direct association between blue sky exposure and cardiovascular disease (CVD) still lacks epidemiological evidence. In this study, we aimed to quantify their relationship via a nationwide prospective cohort in China.MethodWe extracted the baseline data from the China Hypertension Survey (CHS), by enrolling 22,702 participants aged ≥ 35 years without self-reported medical history of CVD from 14 provinces of China between 2012 and 2015 and followed up from 2018 to 2019. A blue day was marked out with no rain, low cloud cover ≤ climatological mean at each station, and visibility at 2 pm ≥ 21.52 km. We calculated the number of blue days at baseline survey year to evaluate the chronic individual blue day exposure. Cox proportional hazards models were employed to calculate the multivariable-adjusted hazard ratio (HR). We implemented subgroup analyses as well to identify potential effect modifications.ResultsA total of 1,096, 993, and 597 incident cases of all-cause mortality, fatal or nonfatal CVD, and stroke occurred during a median follow-up around 5 years, respectively. A 10-day increase in annual blue day exposure was associated with a 3% (95% confidence interval [CI]: 1–6%) and 7% (95% CI: 5–10%) decreased risk of fatal or nonfatal CVD and stroke, respectively. Compared with those exposed to the worst tertile of blue days at baseline, subjects who exposed to the best tertile had a 32% (95% CI: 19–43%) and 43% (95% CI: 29–55%) lower likelihood of developing fatal or nonfatal CVD and stroke, respectively. Negative consistent exposure–response relationships were generally observed between them in the restricted cubic spline model. In the stratified analyses, the cardioprotective effects of blue sky were stronger for females, rural residents, and individuals residing in heavily contaminated areas.ConclusionThis study indicates that blue sky may serve as an independent environmental protective factor against CVD, and informs future policies on fighting air pollution and protecting the blue sky in China.
Nutritional factors for anemia in pregnancy: A systematic review with meta-analysis
Authors: Zhang Jing , Li Quanhong , Song Ying , Fang Liping , Huang Lei , Sun Yu 
Published: October 2022

BackgroundAnemia in pregnancy is a serious threat to maternal and child health and is a major public health problem. However, the risk factors associated with its incidence are unclear and controversial.MethodsPubMed, Ovid Embase, Web of Science, and Cochrane databases were systematically searched (inception to June 27, 2022). The screening of search results, extraction of relevant data, and evaluation of study quality were performed independently by two reviewers.ResultsA total of 51 studies of high quality (NOS score ≥ 7) were included, including 42 cross-sectional studies, six case-control studies, and three cohort studies. Meta-analysis showed that infected parasite, history of malarial attack, tea/coffee after meals, meal frequency ≤ 2 times per day, frequency of eating meat ≤ 1 time per week, frequency of eating vegetables ≤ 3 times per week, multiple pregnancies, multiparous, low household income, no antenatal care, rural residence, diet diversity score ≤ 3, have more than 3 children, history of menorrhagia, underweight, family size ≥ 5, middle upper arm circumference &lt; 23, second trimester, third trimester, birth interval ≤ 2 year were all risk factors for anemia in pregnancy.ConclusionsPrevention of anemia in pregnancy is essential to promote maternal and child health. Sufficient attention should be paid to the above risk factors from the social level and pregnant women's own aspects to reduce the occurrence of anemia in pregnancy.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42022344937.
Effects of psychological intervention on empathy fatigue in nurses: A meta-analysis
Authors: Chen Xiaojuan , Chen Mingdi , Zheng Huang , Wang Chaoyu , Chen Huimin , Wu Qinglan , Liao Huizhao , Zhu Jinru , Lin Junyan , Ou Xudong , Zou Zhihong , Wang Zhiwei , Zheng Zhenzhen , Zhuang Xianrui , Chen Riken 
Published: October 2022

ObjectiveThe purpose of this meta-analysis is to systematically assess the effects of psychological intervention on empathy fatigue among nursing staff.MethodFive electronic databases are searched separately from their establishment to April 8th, 2022. The research team independently performs paper selection, quality assessment, data extraction and analysis for all included studies. PRISMA guidelines are used to report this meta-analysis.ResultsA total of seven randomized controlled trials (RCTs) covering 513 nursing staff are included. The meta-analysis results show that the empathy fatigue score (SMD = −0.22, 95% CI: −0.42~−0.02, P = 0.03) and burnout (SMD = −0.37, 95% CI: −0.56~−0.19, P &lt; 0.001) are lower than the control group. The empathy satisfaction score of the psychological intervention group is higher than that of the control group (SMD = 0.45, 95% CI: 0.27–0.63, P &lt; 0.001). The differences are statistically significant (P &lt; 0.05). Subgroup analysis finds significant heterogeneity in the impact of different departments on psychological intervention at ≥6 weeks (I2 = 71%, P = 0.01) and &lt;6 weeks (I2 = 0%, P = 0.75) (P = 0.05). Different departments also show significant heterogeneity in the effects of psychological intervention: ICU (I2 = 73%, P = 0.02), pediatric (I2 = 53%, P = 0.14) and other departments (I2 = 0%, P = 0.63). The differences are statistically significant (P = 0.0007). Besides, the results show that both mindfulness intervention (SMD = 0.50, 95% CI: 0.24–0.77, P = 0.0002) and other interventions (SMD = 0.41, 95% CI: 0.16–0.65, P = 0.001) are statistically significant difference in the level of empathy satisfaction between the psychological intervention group and the control group.ConclusionPsychological intervention has a coordinated improvement effect on empathy fatigue, empathy satisfaction and burnout, and can also improve the quality of life of nursing staff.
Human mobility variations in response to restriction policies during the COVID-19 pandemic: An analysis from the Virus Watch community cohort in England, UK
Authors: Cheng Tao , Chen Tongxin , Liu Yunzhe , Aldridge Robert W. , Nguyen Vincent , Hayward Andrew C. , Michie Susan 
Published: October 2022

ObjectiveSince the outbreak of COVID-19, public health and social measures to contain its transmission (e.g., social distancing and lockdowns) have dramatically changed people's lives in rural and urban areas globally. To facilitate future management of the pandemic, it is important to understand how different socio-demographic groups adhere to such demands. This study aims to evaluate the influences of restriction policies on human mobility variations associated with socio-demographic groups in England, UK.MethodsUsing mobile phone global positioning system (GPS) trajectory data, we measured variations in human mobility across socio-demographic groups during different restriction periods from Oct 14, 2020 to Sep 15, 2021. The six restriction periods which varied in degree of mobility restriction policies, denoted as “Three-tier Restriction,” “Second National Lockdown,” “Four-tier Restriction,” “Third National Lockdown,” “Steps out of Lockdown,” and “Post-restriction,” respectively. Individual human mobility was measured with respect to the time period people stayed at home, visited places outside the home, and traveled long distances. We compared these indicators across the six restriction periods and across socio-demographic groups.ResultsAll human mobility indicators significantly differed across the six restriction periods, and the influences of restriction policies on individual mobility behaviors are correlated with socio-demographic groups. In particular, influences relating to mobility behaviors are stronger in younger and low-income groups in the second and third national lockdowns.ConclusionsThis study enhances our understanding of the influences of COVID-19 pandemic restriction policies on human mobility behaviors within different social groups in England. The findings can be usefully extended to support policy-making by investigating human mobility and differences in policy effects across not only age and income groups, but also across geographical regions.
Design engineering a walking robotic manipulator for in-space assembly missions
Authors: Nair Manu Harikrishnan , Rai Mini Chakravarthini , Poozhiyil Mithun 
Published: October 2022

In-Space Services aim to introduce sustainable futuristic technology to support the current and growing orbital ecosystem. As the scale of space missions grows, there is a need for more extensive infrastructures in orbit. In-Space Assembly missions would hold one of the key responsibilities in meeting the increasing demand. In the forthcoming decades, newer infrastructures in the Earth’s orbits, which are much more advanced than the International Space Station are needed for in-situ manufacturing, servicing, and astronomical and observational stations. The prospect of in-orbit commissioning a Large Aperture Space Telescope (LAST) has fuelled scientific and commercial interests in deep-space astronomy and Earth Observation. However, the in-situ assembly of such large-scale, high-value assets in extreme environments, like space, is highly challenging and requires advanced robotic solutions. This paper introduces an innovative dexterous walking robotic system for in-orbit assembly missions and considers the Large Aperture Space Telescope system with an aperture of 25 m as the use case. The top-level assembly requirements are identified with a deep insight into the critical functionalities and challenges to overcome while assembling the modular LAST. The design and sizing of an End-over-end Walking Robot (E-Walker) are discussed based on the design of the LAST and the specifications of the spacecraft platform. The E-Walker’s detailed design engineering includes the structural finite element analysis results for space and earth-analogue design and the corresponding actuator selection methods. Results of the modal analysis demonstrate the deflections in the E-Walker links and end-effector in the open-loop due to the extremities present in the space environment. The design and structural analysis of E-Walker’s scaled-down prototype is also presented to showcase its feasibility in supporting both in-orbit and terrestrial activities requiring robotic capabilities over an enhanced workspace. Further, the mission concept of operations is presented based on two E-Walkers that carry out the assembly of the mirror modules. The mission discussed was shortlisted after conducting an extensive trade-off study in the literature. Simulated results prove the dual E-Walker robotic system’s efficacy for accomplishing complex in-situ assembly operations through task-sharing.
MatricS—A novel tool for monitoring professional role development in surgical disciplines
Authors: Necknig U. , Leyh H. , Waidelich R. , Gernhold L. , Kiesewetter J. , Weidenbusch M. 
Published: October 2022

IntroductionMentoring is an effective method for human resource development. Monitoring the process is important for individual mentee/mentor pairs as well as for program directors. Due to individual personality differences of both mentees and mentors and their respective interactions, it is challenging to monitor the individual development process of mentees in a structured manner. This study investigates to what extent a novel instrument, the mentee-based assessment tool for role development of interpersonal competencies in surgical professions (MatricS) can adequately monitor the professional role development process of residents during an established mentoring program.Material and methodsIn a prospective longitudinal study, the competence development of 31 mentees in two subsequent cohorts was assessed by a modified role matrix based on Canadian Medical Education Directives for Specialists. The evaluation focused on three defined roles (D, developer; N, networker; M, multiplicator) at three levels (private, employer-related, national/international) with four stages of development. For validation of mentee self-assessments, the assessments of the respective mentors were recorded alongside. For correlation analyses, Pearson coefficients were calculated, pre-post-comparisons were done by paired t-tests; significance was assumed at p &lt; 0.05, respectively.ResultsMentee self-assessments overall correlated well with the objective mentor assessments (Pearson's r 0.8, p &lt; 0.001). Significant correlations of this magnitude were found for both individual cohorts as well as for all individual roles. The mentees acquired competencies in all roles indicated by significant increases of corresponding MatricS scores. The largest competency gains (mean ± SD) were found in the role D (start: 1.30 ± 0.77, end: 2.13 ± 0.83, p &lt; 0.001). The majority of mentees achieved the prespecified target competency level in &gt;75% of all roles and levels.ConclusionThe role development process during mentoring can be reliably monitored by using MatricS. MatricS scores highly correlate between mentees and mentors, indicating that mentee self-assessments are suitable and sufficient for monitoring. These findings help to lessen the work burden on senior surgeons and thus can help to increase the acceptance of mentoring programs in surgical disciplines.
Incidence of ischemic complications and technical nuances of arteries preservation for insular gliomas resection
Authors: Hou Zonggang , Huang Zhenxing , Li Zhenye , Deng Zhenghai , Li Gen , Xu Yaokai , Wang Mingran , Sun Shengjun , Zhang Yazhuo , Qiao Hui , Xie Jian 
Published: October 2022

IntroductionInsular gliomas have complex anatomy and microvascular supply that make resection difficult. Furthermore, resection of insular glioma is associated with a significant risk of postoperative ischemic complications. Thus, this study aimed to assess the incidence of ischemic complications related to insular glioma resection, determine its risk factors, and describe a single surgeon’s experience of artery-preserving tumor resection.MethodsWe enrolled 75 consecutive patients with insular gliomas who underwent transcortical tumor resection. Preoperative and postoperative demographic, clinical, radiological [including diffusion-weighted imaging (DWI)], intraoperative neurophysiological data, and functional outcomes were analyzed. Motor evoked potentials (MEPs) and radiological characteristics like the relationship between the proximal segment of the lateral lenticulostriate arteries (LLSAs) and the tumor, the flat inner edge sign (the inner edge of the insular glioma is well-defined) or obscure inner edge sign, the distance between the lesion and posterior limb of the internal capsule and the invasion of the superior limiting sulcus by the tumor were analyzed. Strategies such as “residual triangle,” “basal ganglia outline reappearance,” and “sculpting” technique were used to preserve the LLSAs and the main branches of M2 for maximal tumor resection according to the Berger–Sinai classification.ResultsPostoperative DWI showed acute ischemia in 44 patients (58.7%). Moreover, nine patients (12%) had developed new motor deficits, as determined by the treating neurosurgeons. The flat inner edge sign [odds ratio (OR), 0.144; 95% confidence interval (CI), 0.024–0.876) and MEPs (&gt;50%) (OR, 18.182; 95% CI, 3.311–100.00) were significantly associated with postoperative core ischemia, which affected the posterior limb of the internal capsule or corona radiata.ConclusionsInsular glioma resection was associated with a high incidence of ischemia, as detected by DWI, as well as new motor deficits that were determined by the treating neurosurgeons. Insular glioma patients with obscure inner edge signs and intraoperative MEPs decline &gt;50% had a higher risk of developing core ischemia. With our strategies, maximal safe resection of insular gliomas may be achieved.
Comparative study of pelvic sarcoma patients undergoing internal and external hemipelvectomy: A meta-analysis study
Authors: Banskota Nishant , Yang Hongsheng , Fang Xiang , Yuan Dechao , Zhang Wenli , Duan Hong 
Published: October 2022

IntroductionMalignant and giant pelvic tumors are complex and rare, and hemipelvectomies are complex procedures performed for this malignant lesion. Only a few studies had been conducted on the survival and recurrence of pelvic sarcomas patients undergoing internal or external hemipelvectomy. In the present study, we compared internal with external hemipelvectomy in pelvic sarcomas on clinical outcomes by a meta-analysis.MethodsThe survival and recurrence rates of pelvic sarcomas patients were collected from research reports from CNKI, MEDLINE, EMBASE, the Cochrane Database, and Google Scholar until April 2022. The quality of included articles was evaluated by two independent reviewers. Differences between patients undergoing internal and external hemipelvectomy were analyzed based on postoperative survival and recurrence rates.ResultsFive articles were included according to selection criteria. There were 183 patients in total from these studies. Our results showed that there was no significant difference between limb salvage surgery and amputation according to survival; however, patients with internal hemipelvectomy had a lower recurrence rate.ConclusionsInternal hemipelvectomy results in a lower recurrence rate and similar survival rate, while not increasing the risk of metastasis and complications. This study provided more pieces of evidence to support internal hemipelvectomy as a favorable treatment of pelvic sarcomas.
A risk prediction model for evaluating thrombosis extension of muscle calf venous thrombosis after craniotomy
Authors: Li Juhua , Chen Huayu , Liu Mei , Lin Zheng , Ren Xingzhen , Wang Ying , Zou Xingchen , Gu Zejuan 
Published: October 2022

ObjectiveTo explore the risk factors of muscle calf venous thrombosis (MCVT) after craniotomy and construct a risk prediction model, so as to provide tool for evaluating the prognosis of MCVT after craniotomy.MethodsRetrospective analysis was performed on the data of patients undergoing craniotomy complicated with MCVT from January 1, 2018 to December 31, 2020. A prediction model was established by Logistic regression, and the predictive efficacy of the model was tested by ROC curve. The accuracy of the risk model was evaluated by Hosmer-Lemeshow (H-L) test, and the model was verified internally by cross validation.ResultsAmong the 446 patients who underwent craniotomy complicated with MCVT, 112 cases (25.11%) had thrombosis extension. D-dimer, Capirini scores, length of hospital stay, malignant tumor, fracture, use of dehydrating agents and hemostatic agents were independently related to thrombosis extension after craniotomy. The area under ROC curve (AUROC) of the prediction model was 0.918 (0.888, 0.942), and the sensitivity and specificity of the maximum Youden index were 85.3% and 78.2%, respectively. H-L test showed that the prediction model was accurate (χ2 = 12.426, P = 0.133). The internal verification results of the prediction model showed that the AUROC value of the prediction model is 0.892.ConclusionThe prediction model has a good prediction efficacy on the prognosis of post-craniotomy patients complicated with MCVT, and can be used as a tool to evaluate the risk of thrombosis extension.