bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular detection of dengue virus serotypes prevalent in central Kerala and its correlation with disease severity
Authors: R Rugma , Valsan Chithra , Sreekumar E , Sathiavathy KA 
Published: April 2022

Dengue is the most important mosquito-borne viral disease in the world. In 2017, a concerning increase in dengue cases with high mortality was seen in India with Kerala topping the list. Changing pattern of circulating dengue virus serotype and co infection with multiple serotypes contribute to the increasing trend in severity and increased mortality of dengue fever. The present study focused to find the dengue serotypes prevalent in central Kerala and prevalence of co infection with multiple serotypes here with an attempt to correlate these with clinical severity of dengue: This descriptive study was done in the Microbiology department of Jubilee Mission Medical College, Thrissur for a period of 18 months. Blood samples of clinically suspected dengue fever cases which were positive for NS1 antigen and having fever not more than 5 days were subjected to molecular methods to detect dengue virus RNA followed by multiplex RTPCR to find its serotype. Demographic features, clinical details and lab parameters were also collected from each patient. A total of 108 samples positive for Dengue NS1 antigen were subjected to RT-PCR. Among them 61(56.5%) were positive by RT-PCR. All the 4 Dengue serotypes were found with DENV-2 with 30 cases (49.2%) being the predominant serotype followed by DENV-1 with 20 cases (32.8%), DENV-3 with 12 cases (19.6%) and DENV-4 with 2 cases (3.27%). Three cases (4.9%) of co infection with DENV-1,2, DENV-1, 4 and DENV-2,3 were also found. Two among the 108 patients (1.85%) died in the present study. Significant correlation between severity of dengue infection and serotypes could not be found due to very few severe cases encountered during the study. : The dengue serotypes predominant in central Kerala is DENV-2. The prevalence of co infection with multiple serotypes is 4.9% which proves that this area has become hyper endemic to the disease, which increases the risk of emergence of more severe cases.
Comparison and correlation between mandibular morphology among diferent vertical growth patterns: A cephalometric study
Authors: Mahajan Roshni , Thukral Rakesh , Garg Ashish , Tripathi Amit , Singh Choudhary Amit 
Published: April 2022

: In the field of Orthodontics and Dentofacial Orthopedics, in-depth knowledge of mandibular morphology and different types of growth pattern is essential to reach to ideal treatment for every patient.To compare antegonial notch depth, symphysis morphology and ramus morphology among different growth patterns. 2) To correlate antegonial notch depth with other parameters of mandibular morphology.: In this study, lateral cephalogram of total 90 patients were traced. The sample was divided into horizontal, average and vertical growth pattern based on Jarabak’s ratio. The antegonial notch depth, symphysis morphology (i.e. its height, depth, ratio and angle) and ramus morphology (its height and width) were evaluated and analysed statistically. The symphysis ratio is the ratio of symphysis height to symphysis width. : This study revealed that antegonial notch depth, symphysis angle and ramus height shows statistically significant difference among different growth patterns. In vertical growth pattern, antegonial notch depth is positively correlated with symphysis height, symphysis depth, ramus height and ramus width whereas it is negatively correlated with symphysis ratio and symphysis angle and exactly opposite is true for horizontal growing individuals. : This study concluded that there is correlation between mandibular morphology and growth pattern of an individual.
Severe class II div 2 malocclusion with impacted canines- A case report
Authors: Kshetrapal Abhishek 
Published: April 2022

Non surgical correction of severe deep bite malocclusion always poses a challengeespecially when it is associated with a Class II skeletal base. Here a case with severe Class II div 2 malocclusion (&#62;200% deep bite) with impacted canines is presented which was successfully treated non-surgically. Class II div 2 malocclusion, impacted canines, skeletal deep bite, gummy smile
Potencjał działalności kredytowej sektora bankowego w obliczu pandemii COVID-19. Perspektywa credit crunch
Authors: Czechowska Iwona Dorota , Lipiński Czesław , Stawska Joanna , Zatoń Wojciech 
Published: April 2022

Głównym celem opracowania jest analiza dostępności kredytowej. Do podjęcia tego tematu skłoniły nowe przesłanki, związane ze zmianą warunków działania podmiotów gospodarczych w następstwie wybuchu pandemii COVID-19. W połowie roku 2020. zaobserwowano w Polsce, po raz pierwszy od 2009 występowanie w układzie m/m następujących zjawisk: spadek zadłużenia kredytowego sektora przedsiębiorstw niefinansowych, większy niż w okresie globalnego kryzysu finansowego, deklaracja sektora bankowego dotycząca zaostrzenia polityki kredytowej. W takich okolicznościach powstało pytanie o możliwość nadmiernego ograniczania podaży kredytu przez banki, w związku ze skutkami pandemii COVID-19. Efekty pandemii zwiększają prawdopodobieństwo problemów związanych z terminową obsługą zadłużenia. Tendencja polegająca na ograniczaniu podaży kredytu występuje pod nazwą credit crunch. Odpowiedzi na pytanie badawcze, czy w Polsce występuje zagrożenie credit crunch, poszukiwano na podstawie przeglądu literatury oraz badań empirycznych. Mając na uwadze duże znaczenie finansowania kredytowego przedsiębiorstw dla ich aktywności inwestycyjnej, waga dostępności kredytowej jest szczególnie istotna w okresach kryzysu. Wnioski wynikające z przedstawionego materiału analitycznego dają podstawę do stwierdzenia, że zjawisko credit crunch w Polsce nie występuje. Przeprowadzone rozważania teoretyczne oraz analiza empiryczna działalności kredytowej w Polsce wykazały, że nie potwierdziły się obawy dotyczące załamania na rynku podaży kredytów. Sytuacja sektora bankowego w połowie roku 2021 wyglądała dość optymistycznie w krótkim terminie (oprócz nierozwiązanej kwestii mieszkaniowych kredytów walutowych i związanych z nią konsekwencji), ale w perspektywie długoterminowej istotną rolę będzie odgrywać zdiagnozowana pułapka niskiej strukturalnej dostępności kredytowej i chronicznie słabego ukredytowienia polskiej gospodarki. W połączeniu z niską rentownością sektora, wynikającą głównie z wysokich obciążeń fiskalnych będzie to stanowić istotny czynnik hamujący rozwój sektora bankowego w Polsce. Zmiana tego stanu wymaga istotnej rewizji i konsekwentnej realizacji strategii gospodarczej dla Polski poprzez intensyfikację i promowanie przedsięwzięć inwestycyjnych. Z drugiej strony pożądane jest racjonalne (np. elastyczne w zależności od koniunktury gospodarczej) podejście do obciążeń fiskalnych sektora bankowego.
Praca powstała w wyniku realizacji projektu badawczego o nr UMO-2017/26 / D / HS4 / 00954 finansowanego ze środków Narodowego Centrum Nauki.
Aprendizaje Basado en Proyectos en el proceso de enseñanza – aprendizaje Escuela de Educación Básica “Despertar”
Authors: Coronel Bustamante Rosa Angela , Álvarez Meza Michel Yalile , Lozano  Veliz Raquel Jesusa 
Published: April 2022

La presente propuesta está enfocada en Aprendizaje Basado en Proyectos (ABP) en el proceso de enseñanza – aprendizaje, la misma que es una metodología que favorecerá desarrollar el pensamiento crítico y habilidades que servirán como solución en la Escuela de Educación Básica “Despertar”, involucrando al docente con (ABP) como estrategia innovadora para mejorar la calidad educativa de los estudiantes. El objetivo principal que tiene la propuesta es diseñar estrategias para el (ABP) como método innovador para la enseñanza – aprendizaje de los estudiantes, la investigación aplicada fue de carácter descriptiva con enfoque cuantitativo la cual permitió recoger los datos de la institución y realizar el análisis, el método aplicado fue el deductivo, empleado para determinar estrategias innovadoras, la técnica empleada para la recolección de datos fue una encuesta dirigida al personal docente, representantes legales y estudiantes de la institución, las mismas que al realizar un análisis a las preguntas más representativas podemos destacar que se evidenciaron los siguientes resultados: 50% de los docentes aplican la metodología participativa con los estudiantes, 36% de los docentes repiten laclase cuando los estudiantes no comprenden el tema sobre la asignatura impartida, en el análisis realizado a los estudiantes se comprobó que existe un 74% de motivación por parte del docente, sin embargo, existen docentes que siguen empleando la pizarra para impartir las clases y finalmente el 66% de los representantes están contentos con la enseñanza que están recibiendo sus hijos. Esto nos muestra que se está aplicando la metodología adecuada en el proceso de aprendizaje.
Nutrient Availability and Nutrient Uptake by Crop and Weed as Influenced by Stale Seedbed, Mulching and Mechanical Weeding in Okra
Authors: Chacko Seethal Rose , Raj Sheeja K. , Pillai P. Shalini , Jacob D. , Lakshmi P.R. Geetha , Radhakrishnan N.V. , Krishnasree R.K. 
Published: April 2022

Background: Weeds are the major biological constraint in okra due to its slow initial growth and wider row spacing. Due to severe crop weed competition, weeds removed considerable amount of nutrients from the soil. Competition exists between the crop and weed for nutrients results in nutrient deficiencies in crop. Hence the present experiment is formulated to assess the effect of stale seedbed, mulching and mechanical weeding on nutrient availability, nutrient uptake by crop and weed in okra. Methods: Experiment was conducted at Coconut Research Station, Balaramapuram, Thiruvananthapuram, Kerala during Rabi 2020-21. Design adopted for the study was RBD with two factors. The first factor was seedbed preparation (S) and the second factor was weed management (W). Stale seedbed (S1) and normal seedbed (S2) were the two different seedbed preparation methods and dried banana leaf mulch @10 t ha-1 alone (W1), dried banana leaf mulch @10 t ha-1 fb wheel hoe weeding at 30 and 45 DAS (W2), dried banana leaf mulch @10 t ha-1 fb hand weeding at 30 and 45 DAS (W3), wheel hoe weeding at 15, 30 and 45 DAS (W4), hand weeding at 15, 30 and 45 DAS (W5) and weedy check (W6) were the six different weed management options tried. Soil samples were collected after the harvest of the crop to determine the nutrient availability. Weed samples at 30 and 60 DAS and plant samples at harvest were analyzed to determine the NPK content and respective uptake of nutrients were calculated by multiplying the nutrient content with DMP. Result: Stale seedbed significantly enhanced the dry matter production and nutrient uptake by okra at harvest and lowered the nutrient removal by weeds at 30 and 60 DAS. Compared to non-stale, stale seedbed recorded significantly higher fruit yield. Among the weed management, wheel hoe weeding at 15, 30 and 45 DAS, recorded the lowest total weed dry weight at 30 and 60 DAS and resulted in the highest NPK uptake by crop and fruit yield. Uncontrolled weed growth resulted in a loss of 81.33, 18.16 and 50.84 kg N:P:K ha-1 at 30 DAS and 102.09, 57.90 and 55.31 kg N:P:K ha-1 at 60 DAS, respectively. Nutrient removal by weeds was the lowest in wheel hoe weeding at 15, 30 and 45 DAS and the highest in weedy check. It could be concluded that, wheel hoe weeding at 15, 30 and 45 DAS was the best option for the management of weeds, higher nutrient availability and uptake and yield in okra.
Funções motoras e cognitivas de idosos frequentadores de centro de convivência comparados a idosos sedentários
Authors: Vidal Bravalhieri Anna Alice , Oliveira Rodrigues Nathalia , Borges Lino Tayla , Christofoletti Gustavo 
Published: April 2022

Os avanços tecnológicos na saúde contribuíram para um aumento da expectativa de vida e para o envelhecimento populacional. Como um aliado ao envelhecimento ativo, diversas cidades têm possibilitado espaços específicos para idosos, chamados de centros de convivência de idosos (CCI). Os CCI são locais destinados ao desenvolvimento de atividades socioculturais, educativas e físicas que permitem a participação do idoso na vida comunitária. O objetivo deste estudo foi avaliar as funções motoras e cognitivas de idosos frequentadores de CCI na comparação com idosos sedentários. Neste estudo transversal, descritivo e de abordagem quantitativa, 21 idosos foram divididos em três grupos: G1 (idosos que realizam atividades físicas em CCI), G2 (idosos que realizam atividades cognitivas em CCI) e G3 (idosos sedentários). As avaliações envolveram testes de vulnerabilidade (Índice de Vulnerabilidade Clínico Funcional - 20), funcionalidade (Índice de Pfeffer), cognição (Mini Exame do Estado Mental e Trail Making Test), equilíbrio (Escala de Equilíbrio Funcional de Berg) e mobilidade (Timed up and Go). Na comparação estatística, utilizou-se o Teste de Kruskal-Wallis. Os resultados apontaram similaridade entre grupos, para vulnerabilidade e funcionalidade. Houve uma tendência estatística do G1 em apresentar melhor escore motor que os demais. O grupo G2 apresentou pior escore cognitivo que os demais grupos. Já o grupo G3, por não apresentar os piores escores, opta por ficar em casa. Em conclusão, idosos que realizam atividades físicas em CCI tendem a apresentar melhor escore motor. O pior escore cognitivo do grupo G2 pode indicar que o idoso percebeu dificuldades cognitivas diárias e optou por realizar atividades com estimulação cognitiva.
Textual heterogeneity in massive sandstones from the Grès d'Annot and Numidian Flysch: Implications for depositional processes
Authors: Patel Urval S. , Stow Dorrik A.V. , Gardiner Andy , Buckman Jim 
Published: April 2022

ABSTRACT
Vertical bed scale heterogeneity in six massive sandstone beds is investigated using digital image analysis to determine flow processes. Images parallel to the bedding plane and perpendicular to the apparent grain long-axis orientation were acquired to minimize the uncertainty in the grain-size and fabric, and increase the statistical significance of the data. Hypothesis testing was used to reduce the subjectivity in assigning vertical trends within each bed. Results show that a significant part of the deposit contains statistically significant vertical variation in grain-size and fabric (ρ-values &lt; 0.01). At the bed scale, grain-size can be normally graded or non-graded. However, at shorter length scales, complex grading patterns emerge in the different percentiles of the grain-size distribution, including “oscillating,” “diverging,” and “converging” trends involving the fine- and coarse-tail percentile. Grain fabrics in the bedding-parallel sections show a consistently flow-oblique trend with an average azimuthal deviation of 48°, but becoming increasingly flow aligned at the tops of most beds. The majority of the bedding-perpendicular sections show imbrication angles &gt; 15°, with an average imbrication angle of 78°. Both up- and down-current imbrication polarities are observed in equal abundance. These textural trends are interpreted as a product of active near-bed sedimentation processes that operate in high concentration near-bed layers, which develop at the base of concentrated, turbulent flows, and active fluidization processes that operate during sediment deposition. The short length-scale grain-size trends are likely a reflection of fluctuations in the sediment concentration in these near-bed layers and elutriation, which led to differential grain segregation processes influencing the different grain-size percentiles. The high shear stresses and frequent grain interaction in the near-bed layers, with concomitant fluidization, also generate the oblique bedding-parallel fabric and very high imbrication angles.
Multi-proxy provenance of the lower Pennsylvanian Pottsville sandstone of the northern Appalachian basin in Pennsylvania, U.S.A: Paleodrainage, sources, and detrital history
Authors: Monami Shifat J. , Uddin Ashraf , Hames Willis E. 
Published: April 2022

ABSTRACT
The lower Pennsylvanian Pottsville Formation, in the Appalachian foreland basin, constitutes a late Paleozoic clastic wedge formed close to the Appalachian orogenic belt. In this study, we analyzed Pottsville sandstone from the western bituminous and eastern anthracite fields in Pennsylvania to evaluate the detrital history of the sediments. Petrographic modal analyses show that sandstone in the western bituminous field ranges from quartzarenite to sublitharenite, with mean composition of Qt84F1L15; sampled sandstone from the eastern anthracite field is dominated by sublitharenite to litharenite with mean composition of Qt70F2L29. Heavy-mineral assemblages from both fields are dominated by ultrastable minerals (zircon, rutile, and tourmaline), apatite, sphene, spinel, siderite, and abundant opaques. Almost all the studied sandstone samples are garnet-depleted except one from the eastern anthracite field. The chemical composition of chromium- and zinc-rich spinel in samples from both fields might suggest exhumation of an arc terrane and ophiolitic belt with ultramafic igneous rocks. Particularly, the ternary plot of Fe3+–Cr3+–Al3+ end members for the chrome spinels possibly suggest a derivation from an alpine-type peridotite complex. Laser 40Ar/39Ar analyses of detrital muscovite from eastern anthracite fields and western bituminous fields record separate ages, with the former characterized by prominent Middle to Late Ordovician Taconic and Middle Devonian Acadian ages with two discrete modes at 463 and 369 Ma, and the latter dominated by Late Ordovician Taconic, Middle Devonian Acadian, and Late Devonian Neoacadian ages with discrete modes at 445, 397, 360, and 351 Ma. The new data suggest that early Pennsylvanian sedimentation in the Appalachian foreland basin was controlled by southward, southwestward, and westward drainage systems that originated in the Appalachian orogenic belt to the east and northeast.
A Flownet-Based Method for History Matching and Production Prediction of Shale or Tight Reservoirs with Fracturing Treatment
Authors: Zhao Hui , Rao Xiang , Liu Deng , Xu Yunfeng , Zhan Wentao , Peng Xiaoying 
Published: April 2022

Summary
Based on a newly developed physics-based data-driven model FlowNet, this paper presents an effective method for history matching and production prediction of fractured shale or tight reservoirs without any prior information about fracture geometry. In this method, four types of well nodes including fracturing cluster nodes, fracture nodes, stimulated reservoir volume (SRV) nodes, and matrix nodes are allocated in the reservoir. Then, the reservoir model is simplified as a flow network composed of some 1D connection elements between these nodes. Some grids are divided on each connection element, and the grids on the same connection element are of equal width and permeability. Subsequently, a fully implicit nonlinear solver is used to solve flow equations in this FlowNet grid system to obtain pressure, phase saturation, and production rates, etc. Efficient history-matching procedure based on the FlowNet model of the fractured reservoir is used to determine the parameters of connection elements, and then fast production prediction can be conducted. Five numerical examples including single-well depletion, waterflooding development with natural fractures, multiple-well interference, three-phase flow, and an actual waterflooding field case validate that this presented FlowNet-based method can achieve good history matching and production prediction for various flow problems in shale or tight reservoirs with fracturing treatment, and the history-matched transmissibility and volume of connection elements can reflect the existence of high-conductivity fractures.
Hybrid energy system for Dier El Balah quarantine center in Gaza Strip, Palestine
Authors: El-Khozondar Hala , El-batta Fady , EL-Khozondar Rifa , Alramlawi Mansour 
Published: April 2022

Abstract
A new off-grid Hybrid Energy System (HES) for Dier El Balah quarantine center (middle Gaza Strip, Palestine) that was built to host the infected Corona virus (COVID-19) people is studied. The proposed system is made up of three energy sources mainly photovoltaic (PV), wind, and a diesel generator. The HES is developed to adequately supply a load of 3952 KW/day. The technical and economic considerations are presented. HOMER program is used to develop an optimal system from the practical view point. The results revealed the potential of the HES to provide environment friendly, cost-effective and affordable electricity for the Dier El Balah quarantine center, as compared to using only diesel generators with lowest COE equals 0.348 US$/kWh.
Transcriptomic profiling of mouse amygdala during opioid dependence and withdrawal by single-cell RNA sequencing
Authors: Yan Yan , Herlihy Bridget , Boyles Sean , Tao Junyi , Hulme William , Roy Sabita 
Published: April 2022

Abstract
Substance use disorder (SUD) is a complex process in which several neurocircuits are disturbed and various brain regions are involved. The amygdala is a region that mediates the withdrawal effect as well as anxiety and depression-like behaviors. However, the specific transcriptional changes in each cell type during SUD is largely unknown. Here we performed single-cell RNA sequencing and classified all cell types in mouse amygdala under opioid dependence and withdrawal conditions. Our data revealed key biological processes, such as immune response, inflammation, synaptic transmission, and mitochondrial respiration, changed in a distinct manner in different cell populations. Dramatic differences were unraveled in the transcriptional profiles between dependence and withdrawal states. Overall, our work has provided a comprehensive dataset of genes, biological pathways and cell-cell interactions for all the identified cell types in the amygdala, thus expanding our limited understanding of brain alterations during SUD, especially at the molecular and cellular levels.