bluuebunny/crossref_metadata_2025_split huggingface dataset:
Balancing Optimal Large Deviations in Sequential Selection
Authors: Chen Ye , Ryzhov Ilya O. 
Published: September 2022

In the ranking and selection problem, a sampling budget is allocated among a finite number of designs with the goal of efficiently identifying the best. Allocations of this budget may be static (with no dependence on the random values of the samples) or adaptive (decisions are made based on the results of previous decisions). A popular methodological strategy in the simulation literature is to first characterize optimal static allocations by using large deviations theory to derive a set of optimality conditions, and then to use these conditions to guide the design of adaptive allocations. We propose a new methodology that can be guaranteed to adaptively learn the solution to these optimality conditions in a computationally efficient manner, without any tunable parameters, and under a wide variety of parametric sampling distributions.This paper was accepted by Baris Ata, stochastic models and simulation.Supplemental Material: The e-companion and data are available at https://doi.org/10.1287/mnsc.2022.4527.
Fending Off Critics of Platform Power with Differential Revenue Sharing: Doing Well by Doing Good?
Authors: Bhargava Hemant K. , Wang Kitty , Zhang Xingyue (Luna) 
Published: September 2022

Many digital platforms have accrued enormous power and scale, leveraging cross-side network effects between the sides they connect (e.g., producers and consumers or creators and viewers). Platforms motivate a diverse spectrum of producers, large and small, to participate by sharing platform revenue with them, predominantly under a linear revenue-sharing scheme with the same commission rate regardless of producer power or size. Under pressure from society, lawsuits, and antitrust investigations, major platforms have announced revenue sharing designs that favor smaller businesses. We develop a model of platform economics and show that a small-business oriented (SBO) differential revenue sharing design can increase total welfare and outputs on the platform. Although smaller producers almost always benefit from the shift in revenue sharing design, spillover effects can also make large producers better off under some conditions. More interestingly, we show that platforms are the most likely winner under a differential revenue sharing scheme. Hence, an intervention that ostensibly offers concessions and generous treatment to producers might well be self-serving for platforms and good for the entire ecosystem. This paper was accepted by David Simchi-Levi, information systems. Funding: H. K. Bhargava’s work on platform ecosystems was supported by a research excellence gift from Google Apigee in 2018. Supplemental Material: The data files are available at https://doi.org/10.1287/mnsc.2022.4545 .
Manifestations of beta thalassaemia in the dental setting: a case report
Authors: Radia Ria , Loughlin Amanda , Adams Ashok 
Published: September 2022

The craniofacial manifestations of beta thalassaemia are widely reported, and occur as a result of inadequate haematopoiesis leading to marrow space expansion. Secondarily, extramedullary haematopoiesis can occur throughout the body, although this is rarely reported in the paranasal sinuses. We discuss the systemic and craniofacial manifestations of beta thalassaemia major, with a focus on the radiological findings, as illustrated in a case of a 55-year-old male patient who was referred to the dental hospital as a result of complications of thalassaemia. This case report focuses on the effects of thalassaemia that may be encountered in a dental setting and highlights the radiological findings that clinicians should be aware of. CPD/Clinical Relevance: Dental and craniofacial manifestations, and their management, are discussed for patients with beta thalassaemia.
The influence of patriarchy on Nepali-speaking Bhutanese women’s diabetes self-management
Authors: Sharma Aditi , Stuckey Heather , Mendez-Miller Megan , Cuffee Yendelela , Juris Aubrey J. , McCall-Hosenfeld Jennifer S. 
Published: September 2022

Introduction
The Nepali-speaking Bhutanese (NSB) community is a rapidly growing population in Central Pennsylvania. A community-based diabetes education pilot program found a large gender disparity with fewer women in attendance; participants reported that primary household cooks and caretakers were women. This may be an indication of women’s status in the NSB community, their healthcare access, autonomy, and ability to manage their diabetes. Hence, this study aims to understand the manifestations of patriarchy and its impact on NSB women’s diabetes self-management employing a conceptual framework based on Walby’s structures of patriarchy.

Methods
An exploratory feminist qualitative inquiry was conducted. Fifteen NSB women with Type 2 Diabetes were interviewed about their diabetes self-management. Transcripts were coded for key concepts that emerged from the data. A thematic analysis was conducted. Themes were developed inductively through those categories as well as through an a priori approach using the conceptual framework.

Results
Cultural influences such as family structure, religious beliefs, traditional healthcare and gender roles determined NSB women’s patriarchal upbringing and lifestyle. Unpaid household production was largely dependent on women. Multiple immigrations led to poor socioeconomic indicators and marginalization of NSB women. Women’s access to healthcare (including diabetes) was entirely reliant on other family members due to poor autonomy. Women experienced adverse physical and emotional symptoms related to diabetes and their ability and attempts to maintain a healthy diabetes lifestyle was determined by their physical health condition, knowledge regarding good dietary practices and self-efficacy.

Conclusion
Patriarchal practices that start early on within women’s lives, such as child marriage, religious restrictions as well as women’s access to education and autonomy impacted NSB women’s access to healthcare, knowledge regarding their diabetes and self-efficacy. Future interventions tailored for diabetes prevention and self-management among NSB women should factor in patriarchy as an important social determinant of health.
Symptoms and ECG changes precede sudden cardiac death in hypertrophic cardiomyopathy—A nationwide study among the young in Sweden
Authors: Börjesson Erik , Svennblad Bodil , Wisten Aase , Börjesson Mats , Stattin Eva-Lena 
Published: September 2022

Background
Hypertrophic cardiomyopathy (HCM) is a major cause of sudden cardiac death (SCD) in the young. We aimed to characterize detailed family history, symptoms, hospital utilization and ECG changes before SCD.

Methods
We extracted all cases suffering SCD with HCM from the SUDDY cohort, which includes all cases of SCD between 2000–2010 in Sweden among individuals aged 0–35 years along with their controls. We gathered data from mandatory national registries, autopsy reports, medical records, ECGs (including military conscripts), and detailed family history from an interview-based questionnaire (with relatives, post-mortem).

Results
Thirty-eight cases (7 female), mean age 22 years, with HCM were identified. Among these, 71% presented with possible cardiac symptoms (chest pain [26%], syncope [22%], palpitations [37%]), before death; 69% received medical care (vs 21% in controls) within 180 days before death. The majority (68%) died during recreational activity (n = 14) or exercise/competitive sports (n = 12). Fifteen (39%) had a known cardiac disorder prior to death, with HCM being diagnosed pre-mortem in nine cases. 58% presented with abnormal ECG recordings pre-mortem, and 50% had a positive family history (1st-3rd generation) for heart disease.

Conclusion
In this comprehensive, nationwide study of SCD due to HCM, 87% (33/38) of cases had one or more abnormality prior to death, including cardiac symptoms, a positive family history, known cardiac disease or ECG abnormalities. They sought medical care prior death, to a larger extent than controls. These findings suggest that cardiac screening should be expanded beyond competitive athletes to aid SCD prevention in the young population with HCM.
Preeclampsia has an association with both platelet count and mean platelet volume: A systematic review and meta-analysis
Authors: Walle Muluken , Gelaw Yemataw , Getu Fasil , Asrie Fikir , Getaneh Zegeye 
Published: September 2022

BackgroundPreeclampsia (PE) is a pregnancy-specific disorder characterized by endothelial dysfunction, and activation of the coagulation system. Alteration of PLT parameters is the common hematological abnormality observed in women with PE. The main aim of this study was to systematically review previous studies from around the world to generate evidence about the relationship between platelet count (PC) and PE, as well as mean platelet volume (MPV) and PE, by calculating the pooled weighted mean difference (WMD) of PC and MPV between PE and normotensive (NT) groups.MethodsRelevant articles which were published in the English language from January 10, 2011, to January 10, 2021, were systematically searched through PubMed, Web of Science, and African journals online. In addition, reference probing of published articles searching was employed through Google Scholar and Google for searching grey literature. The methodological qualities of articles were assessed using Joana Brigg’s institute critical appraisal checklist. A random-effects model was used to estimate pooled WMD of PLT parameters between the two groups with the respective 95% confidence intervals (CI) using Stata version 11.0. The I2statistics and Egger’s regression test were used to assess heterogeneity and publication bias among included studies, respectively.ResultsA total of 25 articles were included in this systematic review and meta-analysis. Of which, 23 studies were used in each PC and MPV analysis. The overall pooled WMD of PC and MPV between PE and NT groups were -41.45 × 109/L [95% CI; -51.8, -31.0] and 0.98 fl [95% CI; 0.8, 1.1], respectively. The pooled WMD revealed that PC decreased significantly in the PE group compared to the NT group while MPV increased significantly in the PE group.ConclusionsThis systematic review and meta-analysis indicated that there is a significant decrease in PC and a significant increase in MPV during PE development among pregnant women. As a result, a change in these parameters among pregnant women may indicate the development of PE.
The implementation of a culturally tailored parenting support programme for Somali immigrant parents living in Sweden—A process evaluation
Authors: Osman Fatumo , Schön Ulla-Karin , Klingberg-Allvin Marie , Flacking Renée , Tistad Malin 
Published: September 2022

Background
Parental support programmes aim to strengthen family functioning and the parent–child relationship and to promote the mental health of children and parents. However, there is a lack of knowledge on how parenting support programmes can be implemented for newly arrived immigrant parents. This process evaluation describes the implementation of a successful parenting programme for immigrant parents from Somalia and identifies key components of the implementation process with a focus on Reach, Adaptation, and Fidelity of Ladnaan intervention.

Method
This process evaluation considered context, implementation and mechanism of impact, in accordance with the Medical Research Council’s guidance. Data were collected through focus group discussions, a questionnaire, attendance lists, field and reflection notes and observations of the sessions. The data were then analysed using content analysis and descriptive statistics.

Results
Of the 60 parents invited to the parenting programme, 58 participated in the sessions. The study showed that involving key individuals in the early stage of the parenting programme’s implementation facilitated reaching Somali-born parents. To retain the programme participants, parents were offered free transportation. The programme was implemented and delivered as intended. A majority of the parents were satisfied with the programme and reported increased knowledge about children’s rights and the support they could seek from social services.

Conclusions
This study illustrates how a parenting support programme can be implemented for Somali-born parents and provides guidance on how to attract immigrant parents to and engage them in participating in parenting support programmes.
Real-world evidence of the impact of obesity on residual teeth in the Japanese population: A cross-sectional study
Authors: Hayashi Mayu , Morino Katsutaro , Harada Kayo , Miyazawa Itsuko , Ishikawa Miki , Yasuda Takako , Iwakuma Yoshie , Yamamoto Kazushi , Matsumoto Motonobu , Maegawa Hiroshi , Ishikado Atsushi 
Published: September 2022

Background
Tooth loss is associated with nutritional status and significantly affects quality of life, particularly in older individuals. To date, several studies reveal that a high BMI is associated with tooth loss. However, there is a lack of large-scale studies that examined the impact of obesity on residual teeth with respect to age and tooth positions.

Objective
We assessed the impact of obesity on the number and position of residual teeth by age groups using large scale of Japanese database.

Methods
This was a cross-sectional study of 706150 subjects that were included in the database that combined the data from health insurance claims and health check-up, those lacking information about BMI, HbA1c level, smoking status, and the number of residual teeth were excluded. Thus, a total of 233517 aged 20–74 years were included. Subjects were classified into 4 categories based on BMI, and the number of teeth was compared between age-groups. The percentage of subjects with residual teeth in each position was compared between groups with obesity (BMI ≥25.0 kg/m2) and non-obesity. Logistic regression analysis was performed to clarify whether obesity predicts having <24 teeth.

Results
Higher BMI was associated with fewer teeth over 40s (P for trend <0.0001 when <70s). Obesity was associated with the reduction of residual teeth in the maxillary; specifically, the molars were affected over the age 30. Smoking status further affected tooth loss at positions that were not affected by obesity alone. After adjusting for age, sex, smoking status, and HbA1c ≥6.5%, obesity remained an independent predictive factor for having <24 teeth (ORs: 1.35, 95% CIs: 1.30–1.40).

Conclusions
We found that an increase in BMI was associated with a decrease in the number of residual teeth from younger ages independently of smoking status and diabetes in the large scale of Japanese database.
Neurofilament light chain in blood as a diagnostic and predictive biomarker for multiple sclerosis: A systematic review and meta-analysis
Authors: Ning Liangxia , Wang Bin 
Published: September 2022

Background
Neurofilament light chain (NfL) in cerebrospinal fluid (CSF) is a biomarker of multiple sclerosis (MS). However, CSF sampling is invasive and has limited the clinical application. With the development of highly sensitive single-molecule assay, the accurate quantification of the very low NfL levels in blood become feasible. As evidence being accumulated, we performed a meta-analysis to evaluate the diagnostic and predictive value of blood NfL in MS patients.

Methods
We performed literature search on PubMed, EMBASE, Web of Science and Cochrane Library from inception to May 31, 2022. The blood NfL differences between MS vs. controls, MS vs. clinically isolated syndrome (CIS), progressive MS (PMS) vs. relapsing-remitting MS (RRMS), and MS in relapse vs. MS in remission were estimated by standard mean difference (SMD) and corresponding 95% confidence interval (CI). Pooled hazard ratio (HR) and 95%CI were calculated to predict time to reach Expanded Disability Status Scale (EDSS) score≥4.0 and to relapse.

Results
A total of 28 studies comprising 6545 MS patients and 2477 controls were eligible for meta-analysis of diagnosis value, and 5 studies with 4444 patients were synthesized in analysis of predictive value. Blood NfL levels were significantly higher in MS patients vs. age-matched controls (SMD = 0.64, 95%CI 0.44–0.85, P<0.001), vs. non-matched controls (SMD = 0.76, 95%CI 0.56–0.96, P<0.001) and vs. CIS patients (SMD = 0.30, 95%CI 0.18–0.42, P<0.001), in PMS vs. RRMS (SMD = 0.56, 95%CI 0.27–0.85, P<0.001), and in relapsed patients vs. remitted patients (SMD = 0.54, 95%CI 0.16–0.92, P = 0.005). Patients with high blood NfL levels had shorter time to reach EDSS score≥4.0 (HR = 2.36, 95%CI 1.32–4.21, P = 0.004) but similar time to relapse (HR = 1.32, 95%CI 0.90–1.93, P = 0.155) compared to those with low NfL levels.

Conclusion
As far as we know, this is the first meta-analysis evaluating the diagnosis and predictive value of blood NfL in MS. The present study indicates blood NfL may be a useful biomarker in diagnosing MS, distinguishing MS subtypes and predicting disease worsening in the future.
Risk factors of early neonatal death in East Nusa Tenggara, Indonesia: a case-control study
Authors: Davidz Irene K.L.A. , Kuntoro Kuntoro , Joewono Hermanto T. , Irwanto Irwanto 
Published: September 2022

Background The neonatal mortality in East Nusa Tenggara is still high, contributes up to 75% of all neonatal death and more than 70% of early neonatal death which occurred less than 7 days after birth..
Objective This study aimed to analyze the risk factors of early neonatal death in East Nusa Tenggara.
Methods This case control study was conducted in 18 districts of East Nusa Tenggara, Indonesia. The case was newborn death, while the control was alive newborn during the early neonatal period. The data was obtained from the maternal and neonatal medical record that was kept in provincial health office and each health district office. An interview with mothers was performed if needed. The observed variables were the early neonatal death as a dependent variable and various independent variables.
Results The early neonatal death was associated with maternal age under 20 or over 35 years old (OR=1.8; 95%CI 1.1 to 3.1; P=0.032), the history of stillbirth (OR=27.5; 95%CI 11.6 to 64.5; P=0.000), mother with tuberculosis (OR=15.3; 95%CI 1.7 to 137.3; P=0.015), mother with hyperthyroid (OR=15.5; 95%CI 2.2 to 107; P=0.006), the risk for premature labor (OR= 4.5; 95%CI 2.3 to 8.7; P=0.000), prolonged labor (OR=2.3; 95%CI 1.2 to 4.8; P=0.020), the delivery not in a health facility (OR=18.6; 95%CI= 6.5 to 52.7; P=0.000), low birth weight infants (OR=5.6; 95%CI 3 to 10.3; P=0.000), and asphyxia (OR=25.2; 95%CI 95% 9.9 to 64.5; P=0.000).
Conclusions Increased early neonatal death is associated with maternal age, history of stillbirth, mother with hyperthyroid or tuberculosis, prolonged or risk for premature labor, delivery not in a health facility, low birth weight infants, and asphyxia.
Professores e a relação entre hábito da leitura e eficiência na recepção e produção de textos
Authors: Cristianini Adriana Cristina 
Published: September 2022

Valendo-se de uma pesquisa com docentes inseridos em um programa especial de formação universitária que resultou em dissertação de mestrado, pôde-se observar que a capacidade de recepção e produção de textos se desenvolve somente com o exercício constante dessas práticas. A seleção das partes essenciais, a captação da macroestrutura, o uso da argumentação, os elementos coesivos, o emprego das metarregras, todos os processos são conseqÃ¼ências do grau de experiência desenvolvida pelo leitor/autor do texto. Este trabalho apresenta algumas das observações feitas no decorrer da pesquisa e, para resultar em algum tipo de utilidade, deve ser divulgada, principalmente Ã queles que foram objeto de estudo e a seus pares.
Forbidding the reading of the Kashshāf: clarifying the Mamluk era reception of Zamakhsharī’s Qurʾān commentary
Authors: Ally Shuaib 
Published: September 2022

Abstract
The Qurʾān commentary of Zamakhsharī (d. 538/1144), his Kashshāf, gained wide acclaim shortly after being written, and was widely used in research and teaching throughout the Islamic world. This favourable reception was largely due to its new rhetorical insights on how ideas are articulated in the Qurʾān through specific linguistic constructions. The work was also critiqued for its Muʿtazilī content, the work viewed with suspicion for championing – surreptitiously at that – the heterodox interpretations of that theological school. Appraisal and critique formed much of the basis for scholarly engagement with this work in the form of teaching and commentary writing, especially the form of supercommentary writing (ḥawāshī) the Kashshāf initiated. That Mamluk scholarly culture had an overly negative response to the Kashshāf for theological reasons has been vastly overstated in recent scholarship, possibly due to a tendency to view theology as a sufficient impetus driving past intellectual activity. This general portrayal derives from specific Mamluk scholars being depicted as warning against the book, forbidding its study, calling for it to be banned, and undermining or disparaging others for supporting it. This negative reception has also served to justify the transition in the Islamic world to the tafsīr of Bayḍāwī, a work which largely excised the Muʿtazilism of the Kashshāf. This article reconsiders the evidence for an overall negative Mamluk era reception of the Kashshāf, with specific reference to the activities of those scholars whose depiction contributes to an inaccurate portrayal of a crucial moment in tafsīr history, both for the activities of Mamluk era scholars themselves, as well as the subsequent shift to the use of Bayḍāwī.
Double Implementation in Dominant Strategy Equilibria and Ex-Post Equilibria with Private Values
Authors: Hagiwara Makoto 
Published: September 2022

Abstract
We consider the implementation problem for incomplete information and private values. We investigate double implementability of social choice functions in dominant strategy equilibria and ex-post equilibria. We define a new strategic axiom that implies “strategy-proofness” and that is implied by “secure strategy-proofness,” but the converse of these relationships does not hold. We call it “weak secure-strategy-proofness.” We show that a social choice function is doubly implementable if and only if it is weakly securely-strategy-proof.
Role of MMP-2 and CD147 in kidney fibrosis
Authors: Cheng Zhengyuan , Zhang Xiaojuan , Zhang Yu , Li Li , Chen Pingsheng 
Published: September 2022

Abstract
Matrix metalloproteinase-2 (MMP-2) and cluster of differentiation 147 (CD147) both play important roles in the development of kidney fibrosis, and CD147 can induce the production and activation of MMP-2. In the early stage of kidney fibrosis, MMP-2 promotes extracellular matrix (ECM) production and accelerates the development of kidney fibrosis, while in the advanced stage, MMP-2 activity decreases, leading to reduced ECM degradation and making it difficult to alleviate kidney fibrosis. The reason for the decrease in MMP-2 activity in the advanced stage is still unclear. On the one hand, it may be related to hypoxia and endocytosis, which lead to changes in the expression of MMP-2-related active regulatory molecules; on the other hand, it may be related to insufficient CD147 function. At present, the specific process by which CD147 is involved in the regulation of MMP-2 activity is not completely clear, and further in-depth studies are needed to clarify the roles of both factors in the pathophysiology of kidney fibrosis.