bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Informasi Pengendalian Stok Bahan Baku Pada CV Style Promo Collection Dengan Menggunakan Metode Economic Order Quantity
Authors: Cahyono Lukman Arief , Anita Anita , Kanthi Yekti Asmoro 
Published: March 2022

Pengendalian stok bahan baku merupakan hal yang sangat penting dalam menunjang proses produksi namun, jika pengendalian stok bahan baku tidak terkendali dengan baik maka akan berdampak pada dead stock dan kekurangan bahan baku yang berdampak pada keterlambatan proses produksi dan menurunya harga jual bahan tersebut. Permasalahan tersebut terjadi saat ini pada CV Style Promo Collection, yang sedang mengalami masalah tersebut dan membutuhkan sebuah sistem untuk membantu mengendalikan stok bahan baku agar permasalahan yang terjadi saat ini dapat teratasi dengan sistem yang akan dibuat, untuk menambah tingkat keberhasilan dalam pengendalian stok bahan baku maka digunakan metode economic order quantity dalam proses perhitungan jumlah bahan baku yang harus dipesan pada saat itu. Dari pembuatan sistem yang baru ini dapat memajemen stok bahan baku dengan baik karena pada proses pemesanan bahan baku sudah ditentukan dengan perhitungan otomatis serta terdapat informasi mengenai safety stok dan kapan pemesanan kembali dilakukan.
Peramalan Pembelian Barang Menggunakan Metode Single Moving Average Studi Kasus Toko LADIES.ID
Authors: Kusuma Erwin Triwida , Widodo Sugeng , Aminah Siti 
Published: March 2022

Perkembangan teknologi sangatlah pesat, salah satunya pemanfaatan penggunaan internet dan sistem-sistem online yang terdapat didalamnya. Salah satu sistem yang terus dikembangkan dan terasa manfaatnya adalah sistem penunjang keputusan. Sistem penunjang keputusan sangat membantu dalam mengambil suatu keputusan atau mencarikan solusi terbaik, pada toko Ladies.id masih melakukan pencatatan penjualan barang secara manual. Pembelian barang yang dilakukan secara perkiraan manual sehingga mengakibatkan penumpukan stok barang dikarenakan pembelian barang yang terlalu banyak. Pada penelitian ini menggunakan metode Single Moving Average dengan membandingkan perhitungan 3, 4 dan 5 ordo, sedangkan untuk perhitungan kesalahan menggunakan RMSE (Root Mean Squared Error) dan juga MAPE (Mean Absolute Squared Error). Hasil dari contoh perhitungan celana penelitian ini adalah dengan menghitung menggunakan 3 ordo didapatkan hasil RMSE sebesar 41.3797 dan juga MAPE sebesar 37.1934. Kemudian dengan menggunakan perhitungan 4 ordo didapatkan hasil RMSE sebesar 38.2624 dan MAPE sebesar 34.8641 dan yang terakhir perhitungan menggunakan 5 ordo mendapatkan hasil RMSE sebesar 39.6775 dan MAPE sebesar 36.8851. Kesimpulan yang didapat adalah perhitungan menggunakan 4 ordo mendapatkan hasil yang terkecil sehingga dapat disimpulkan bahwa 4 ordo adalah rekomendasi terbaik untuk meramalkan pembelian celana selanjutnya. Setiap barang dalam toko Ladies.id menggunakan perhitungan 3, 4 dan 5 ordo untuk mendapatkan hasil, dari perhitungan tersebut dibandingkan dan hasil yang memiliki nilai RMSE dan MAPE terkecil yang akan digunakan untuk rekomendasi pembelian selanjutnya.
Sistem Pendukung Keputusan Pemilihan Pondok Pesantren Tahfizhul Qur’An Terbaik Di Malang Menggunakan Metode Analitycal Hierarchy Process Dan Promethee
Authors: Prasetyo Eko Teguh , Prastiningtyas Diah Arifah , Kartikasari Meivi 
Published: March 2022

Pondok pesantren merupakan salah satu lembaga pendidikan yang menyelenggarakan pendidikan non-formal di bidang agama islam. Banyak pesantren yang melaksanakan program menghafalan Al-quran (tahfizhul quran). Menghafal Al-quran merupakan kegiatan yang sangat mulia di mata Allah SWT, karena Nabi Sallallaahu'alaihi Wasallam bersabda yang artinya “sebaik-baik kalian adalah yang mempelajari Al-Qur’an dan mengajarkannya” (HR. Al-Bukhari 4639). Di Malang sendiri banyak pesantren tahfizhul Qur'an yang memiliki kelebihan dan kekurangan masing-masing, sehingga membuat sebagian orang bingung menentukan kemana mereka atau anaknya akan belajar. Atas dasar permasalahan tersebut maka diperlukan suatu sistem untuk mendukung pengambilan keputusan dalam pemilihan pondok pesantren tahfizhul Qur'an di Malang dengan menggunakan metode Analitycal Hierarchy Process (AHP) dan Promethee. Tujuan dari sistem ini adalah untuk dapat membantu sebagian masyarakat dalam memilih pondok pesantren tahfizhul Quran dengan kriteria sistem pendidikan, tingkat pendidikan, fasilitas, kondisi lingkungan, reputasi pondok, alumni dan biaya. Metode AHP digunakan untuk mencari bobot kriteria sedangkan metode Promethee digunakan untuk menentukan peringkat pondok. Setelah dilakukan analisis, perancangan, implementasi dan pengujian sistem, maka dapat disimpulkan bahwa sistem berhasil dibuat dengan menggunakan bahasa pemograman PHP dengan mengimplementasikan metode AHP dan Promethee, sehingga didapatkan saran pondok yang terbaik dengan hasil perhitungan pada system hasilnya sama dengan perhitungan manual yang telah dihitung sebelumnya.
Sistem Informasi Administrasi Dan Keuangan GMIT Ebenhaezer Larantuka Berbasis Web Guna Mempermudah Laporan Keuangan
Authors: Sakaria Setiabudi , Triwibowo Eriech Ragil , Cahyadiana Windarini 
Published: March 2022

Di era digital saat ini, perkembangan kehidupan masyarakat makin luas dan tak terbatas dengan hadirnya internet,, termasuk jugga termasuk Gereja GMIT Ebenhaezer di Larantuka yang saat ini masih menggunakan cara manual dalam melakukan administrasi keuangannya. Masalah yang terjadi saat ini antara lain kesulitan dalam pengolahan data, dan proses perhitungan pemasukan dan pengeluaran uang kas Gereja serta laporan untuk para majelis dan Hamba Tuhan. Penelitian terkait sebelumnya antara lain : Perancangan Sistem Informasi Administrasi Jemaat Gereja St. Padre Pie Langke Majok Manggarai, Nusa Tenggara Timur [1], yang menitkberatkan pada masalah administrasi. Dalam penelitian dan pembuatan aplikasi administrasi yang dibuat dengan PHP dan MYSQL ini ditujukan untuk mengatasi masalah yang terjadi saat ini yaitu Pengolahan data adminstrasi, perhitungan pemasukan dan pengeluaran kas serta laporan keuangan yang dibutuhkan oleh Majelis dan Gembala untuk pengambilan keputusan untuk mempermudah pembuatan laporan keuangan gereja agar transparan dalam pengelolahan keuangan sekaligus pertanggungjawaban terhadap jemaat gereja yang telah memberikan dana pada gereja ini.
The Mediator Role of Resilience in the Relationship between Sensation-Seeking, Happiness and Subjective Vitality
Authors: KAŞIKCI Furkan , PEKER Adem 
Published: March 2022

Sensation-seeking, subjective vitality and happiness are interrelated constructs in the current literature. However, there is presently no research on how the relationship between these concepts is affected. The aim of this research is to examine the mediating effect of resilience in the relationship between them, thus bridging a large gap in the field. The group of participants in the research consisted of a total of 519 university students; 384 (74%) of them women and 135 (26%) of them men. We used sensation seeking, resilience, subjective vitality and Oxford happiness scales in the research. We used mediation analysis to determine the indirect effect of resilience between sensation seeking and subjective vitality and happiness. The findings revealed a low-level, positively significant relationships between sensation seeking and resilience, subjective vitality, and happiness and show that resilience has a mediating role in the relationship between the concepts. Moreover, a high level of psychological resilience increases subjective vitality and happiness. Based on these findings, guidance and psychological counselors in schools may be able to better guided on improving the mood of students.
Anahtar Kelimeler
Happiness, resilience, sensation seeking, subjective vitality, positive psychology
Designing Special Nonmetallic Superalkalis Based on a Cage-like Adamanzane Complexant
Authors: Ye Ya-Ling , Pan Kai-Yun , Ni Bi-Lian , Sun Wei-Ming 
Published: March 2022

In this study, to examine the possibility of using cage-like complexants to design nonmetallic superalkalis, a series of X@36adz (X = H, B, C, N, O, F, and Si) complexes have been constructed and investigated by embedding nonmetallic atoms into the 36adamanzane (36adz) complexant. Although X atoms possess very high ionization energies, these resulting X@36adz complexes possess low adiabatic ionization energies (AIEs) of 0.78–5.28 eV. In particular, the adiabatic ionization energies (AIEs) of X@36adz (X = H, B, C, N, and Si) are even lower than the ionization energy (3.89 eV) of Cs atoms, and thus, can be classified as novel nonmetallic superalkalis. Moreover, due to the existence of diffuse excess electrons in B@36adz, this complex not only possesses pretty low AIE of 2.16 eV but also exhibits a remarkably large first hyperpolarizability (β0) of 1.35 × 106 au, indicating that it can also be considered as a new kind of nonlinear optical molecule. As a result, this study provides an effective approach to achieve new metal-free species with an excellent reducing capability by utilizing the cage-like organic complexants as building blocks.
Effect of Chinese Patent Medicines on Ocular Fundus Signs and Vision in Calcium Dobesilate-Treated Persons With Non-Proliferative Diabetic Retinopathy: A Systematic Review and Meta-Analysis
Authors: Zhang Yuehong , An Xuedong , Duan Liyun , Jin De , Duan Yingying , Zhou Rongrong , Zhang Yuqing , Kang Xiaomin , Lian Fengmei 
Published: March 2022

BackgroundDiabetic retinopathy (DR), one of the commonest microvascular complications in diabetic patients, is featured by a series of fundus lesions. Conventional Western medicine therapies for DR are always with modest treatment outcome. This paper is to assess the ocular fundus signs, vision and safety of Chinese patent medicines (CPMs) as an add-on treatment for DR.Method7 electronic databases were searched to determine eligible trials. Randomized controlled trials (RCTs) of non-proliferative diabetic retinopathy (NPDR) in which the intervention group received CPMs combined with calcium dobesilate (CD), and the control group received only CD were included for analysis. Two reviewers extracted the data independently. Results expressing as mean differences (MD) and relative risks (RR) were analyzed with a fixed-effects or random-effects models.Results19 RCTs involved 1568 participants with 1622 eyes met our inclusion criteria. The results suggested that compared with CD alone, CPMs plus CD for NPDR was superior at reducing the microaneurysm volume (MD -3.37; 95% confidence interval [CI], -3.59 to -3.14), microaneurysm counts (MD -2.29; 95%CI -2.97 to -1.61), hemorrhage area (MD -0.79; 95%CI -0.83 to -0.75), and macular thickness (MD -59.72; 95%CI -63.24 to -56.20). Participants in CPMs plus CD group also achieved a better vision. No obvious adverse events occurred.ConclusionCPMs as an add-on therapy for NPDR have additional benefits and be generally safe. This meta‐analysis demonstrated that CPMs combined with CD could improve retinal microaneurysm, hemorrhage, macular thickness, visual acuity, fasting blood glucose (FBG), and glycosylated hemoglobin (HbAlc) compared with CD alone. Further studies are needed to provide more conclusive evidence.Systematic Review RegistrationPROSPERO https://www.crd.york.ac.uk/prospero/, identifier CRD42021257999.
Endovascular Treatment and Angiographic Characteristics of Aneurysms at the Origin of the Anterior Choroidal Artery
Authors: Wang Yiheng , Yu Jinlu 
Published: March 2022

BackgroundThe information available about the variations and anatomy of the anterior choroidal artery (AchA) with aneurysm at the origin of the vessel and the outcomes of endovascular treatment (EVT) for AchA aneurysms is incomplete.Materials and MethodsA retrospective study of 54 consecutive patients who were admitted to our hospital with a diagnosis of AchA aneurysm and treated with EVT was performed. The variations and anatomy of the AchA and the outcomes of EVT for AchA aneurysms were analyzed.ResultThe 54 patients were aged 35–82 years (mean age, 56.1 ± 19.7 years) and included 32 females (59.3%, 32/54). Regarding AchA anatomy, 63.5% of AchAs had a typical S-shaped course. The diameter of the AchA origin averaged 0.8 ± 0.3 mm. Of all the AchA aneurysms, 51.9% were ruptured. The diameter of AchA aneurysms averaged 4.1 ± 2.4 mm. Moreover, 40.7% of 54 cases had multiple aneurysms. EVT was assisted with stenting for 25.9% of 54 AchA aneurysms. An immediate Modified Raymond-Roy Classification grade of I was obtained in 96.3% of AchA aneurysm cases. After EVT, the ischemic complication rate was 13%. In total, 83% of patients had good outcomes, with a Glasgow Outcome Scale score of 4–5. Follow-up angiography showed acceptable treatment results in this study.ConclusionThe study showed that the AchA had a complex angiographic anatomy in cases with aneurysms at the origin of the vessel and that the anatomical features can be helpful in EVT. EVT for aneurysms at the origin of the AchA had good outcomes.
Feeding and Manual Brushing Influence the Release of Oxytocin, ACTH and Cortisol Differently During Milking in Dairy Cows
Authors: Wredle Ewa , Svennersten-Sjaunja Kerstin , Munksgaard Lene , Herskin Mette S. , Bruckmaier Rupert M. , Uvnäs-Moberg Kerstin 
Published: March 2022

AimThis study aimed to examine the effects of feeding or abdominal brushing on the release of the hormones oxytocin, ACTH and cortisol during milking in dairy cows.MethodsTwelve cows in early lactation were used (2 × 2 factorial experimental design), testing the effects of two types of sensory stimulation during milking over a 3 day period; feeding concentrate or manual abdominal brushing (1 stroke/s). Blood samples for hormone analyses were collected at time at −15, −1, 0 (onset of cluster), every min for 8 min, at 10, 12, 14, 16, 30, and 60 min. Hormone levels were assayed and AUC was calculated.ResultsMilking was associated with an immediate and significant rise of oxytocin. When milking was combined with feeding, significantly higher levels of oxytocin were observed at 2 and 4 mins (p &lt; 0.05). No effect of brushing on oxytocin levels was observed. Milking alone was associated with a significant rise of ACTH levels. Feeding in connection with milking reduced the immediate rise of ACTH levels (p &lt; 0.05) and AUC (p &lt; 0.02), whereas no effects of brushing were found. Milking caused a progressive rise of cortisol levels. Concomitant feeding did not influence cortisol levels, whereas brushing significantly decreased cortisol levels at 1, 5 and 14 mins after onset of milking (p &lt; 0.05).ConclusionFeeding increases oxytocin release in response to milking and decreases ACTH levels. Abdominal brushing did not influence these variables, but decreased cortisol levels. These data demonstrate that activation of afferent vagal nerve fibres and of cutaneous sensory nerves originating from the abdominal skin in front of the udder influence milking related hormone release differently.
Bone Mineral Density and Current Bone Health Screening Practices in Friedreich’s Ataxia
Authors: Dunn Julia , Tamaroff Jaclyn , DeDio Anna , Nguyen Sara , Wade Kristin , Cilenti Nicolette , Weber David R. , Lynch David R. , McCormack Shana E. 
Published: March 2022

IntroductionFriedreich’s Ataxia (FRDA) is a progressive neurological disorder caused by mutations in both alleles of the frataxin (FXN) gene. Impaired bone health is a complication of other disorders affecting mobility, but there is little information regarding bone health in FRDA.MethodsDual energy X-ray absorptiometry (DXA) scan-based assessments of areal bone mineral density (aBMD) in individuals with FRDA were abstracted from four studies at the Children’s Hospital of Philadelphia (CHOP). Disease outcomes, including the modified FRDA Rating Scale (mFARS), were abstracted from the FRDA Clinical Outcomes Measures Study (FACOMS), a longitudinal natural history study. A survey regarding bone health and fractures was sent to individuals in FACOMS-CHOP.ResultsAdults with FRDA (n = 24) have lower mean whole body (WB) (–0.45 vs. 0.33, p = 0.008) and femoral neck (FN) (–0.71 vs. 0.004, p = 0.02) aBMD Z-scores than healthy controls (n = 24). Children with FRDA (n = 10) have a lower WB-less-head (–2.2 vs. 0.19, p &lt; 0.0001) and FN (–1.1 vs. 0.04, p = 0.01) aBMD than a reference population (n = 30). In adults, lower FN aBMD correlated with functional disease severity, as reflected by mFARS (R = –0.56, p = 0.04). Of 137 survey respondents (median age 27 y, 50% female), 70 (51%) reported using wheelchairs as their primary ambulatory device: of these, 20 (29%) reported a history of potentially pathologic fracture and 11 (16%) had undergone DXA scans.ConclusionsLow aBMD is prevalent in FRDA, but few of even the highest risk individuals are undergoing screening. Our findings highlight potential missed opportunities for the screening and treatment of low aBMD in FRDA.
Phenotypic Spectrum and Prognosis of Epilepsy Patients With GABRG2 Variants
Authors: Yang Ying , Niu Xueyang , Cheng Miaomiao , Zeng Qi , Deng Jie , Tian Xiaojuan , Wang Yi , Yu Jing , Shi Wenli , Wu Wenjuan , Ma Jiehui , Li Yufen , Yang Xiaoling , Zhang Xiaoli , Jia Tianming , Yang Zhixian , Liao Jianxiang , Sun Yan , Zheng Hong , Sun Suzhen , Sun Dan , Jiang Yuwu , Zhang Yuehua 
Published: March 2022

ObjectiveThis study aimed to obtain a comprehensive understanding of the genetic and phenotypic aspects of GABRG2-related epilepsy and its prognosis and to explore the potential prospects for personalized medicine.MethodsThrough a multicenter collaboration in China, we analyzed the genotype-phenotype correlation and antiseizure medication (ASM) of patients with GABRG2-related epilepsy. The three-dimensional protein structure of the GABRG2 variant was modeled to predict the effect of GABRG2 missense variants using PyMOL 2.3 software.ResultsIn 35 patients with GABRG2 variants, 22 variants were de novo, and 18 variants were novel. The seizure onset age was ranged from 2 days after birth to 34 months (median age: 9 months). The seizure onset age was less than 1 year old in 22 patients (22/35, 62.9%). Seizure types included focal seizures (68.6%), generalized tonic-clonic seizures (60%), myoclonic seizures (14.3%), and absence seizures (11.4%). Other clinical features included fever-sensitive seizures (91.4%), cluster seizures (57.1%), and developmental delay (45.7%). Neuroimaging was abnormal in 2 patients, including dysplasia of the frontotemporal cortex and delayed myelination of white matter. Twelve patients were diagnosed with febrile seizures plus, eleven with epilepsy and developmental delay, two with Dravet syndrome, two with developmental and epileptic encephalopathy, two with focal epilepsy, two with febrile seizures, and four with unclassified epilepsy. The proportions of patients with missense variants in the extracellular region and the transmembrane region exhibiting developmental delay were 40% and 63.2%, respectively. The last follow-up age ranged from 11 months to 17 years. Seizures were controlled in 71.4% of patients, and 92% of their seizures were controlled by valproate and/or levetiracetam.ConclusionThe clinical features of GABRG2-related epilepsy included seizure onset, usually in infancy, and seizures were fever-sensitive. More than half of the patients had cluster seizures. Phenotypes of GABRG2-related epilepsy were ranged from mild febrile seizures to severe epileptic encephalopathies. Most patients with GABRG2 variants who experienced seizures had a good prognosis. Valproate and levetiracetam were effective treatments for most patients.
Efficacy and Safety of Complementary Therapy With Jing Si Herbal Tea in Patients With Mild-To-Moderate COVID-19: A Prospective Cohort Study
Authors: Hsieh Po-Chun , Chao You-Chen , Tsai Kuo-Wang , Li Chung-Hsien , Tzeng I-Shiang , Wu Yao-Kuang , Shih Cheng Yen 
Published: March 2022

BackgroundSince late 2019, there has been a global COVID-19 pandemic. To preserve medical capacity and decrease adverse health effects, preventing the progression of COVID-19 to severe status is essential. Jing-Si Herbal Tea (JSHT), a novel traditional Chinese medicine formula was developed to treat COVID-19. This study examined the clinical efficacy and safety of JSHT in patients with mild-to-moderate COVID-19.MethodsIn this prospective cohort study, we enrolled 260 patients with mild-to-moderate COVID-19. The enrolled patients were divided into the JSHT (n = 117) and control (n = 143) groups. Both groups received standard management. The JSHT group was treated with JSHT as a complementary therapy.ResultsCompared with standard management alone, JSHT combined with standard management more effectively improved the reverse transcription–polymerase chain reaction cycle threshold value, C-reactive protein level, and Brixia score in the adult patients with mild-to-moderate COVID-19, especially in the male and older patients (those aged ≥60 years). The results revealed that the patients treated with JSHT combined with standard management had 51, 70, and 100% lower risks of intubation, Medisave Care Unit admission, and mortality compared with those receiving standard management only.ConclusionsJSHT combined with standard management more effectively reduced the SARS-CoV-2 viral load and systemic inflammation and alleviated lung infiltrates in the patients with mild-to-moderate COVID-19, especially in the male and older patients (those aged ≥60 years). JSHT combined with standard management may prevent critical status and mortality in patients with mild-to-moderate COVID-19. JSHT is a promising complementary therapy for patients with mild-to-moderate COVID-19.
Breast Cancer Mortality Trends and Predictions to 2030 and Its Attributable Risk Factors in East and South Asian Countries
Authors: Mubarik Sumaira , Sharma Rajesh , Hussain Syeda Rija , Iqbal Mujahid , Nawsherwan  , Liu Xiaoxue , Yu Chuanhua 
Published: March 2022

BackgroundAmidst the rising breast cancer burden in Asia, we aim to predict the future mortality risk due to breast cancer and identify the risk-attributable deaths for breast cancer among East and South Asian countries.MethodsWe used country-level data to predict the trends in the next decade relating to female breast cancer mortality by employing data from 1990 to 2019 from the Global Burden of Disease 2019 study. We used the stochastic mortality modeling and prediction techniques to forecast the age-specific and risk-attributable breast cancer mortality trends at the regional and national levels of East and South Asia.ResultsThe number of deaths caused by the breast cancer is predicted to increase in East and South Asian countries in the next decade (2020–2030). Age-standardized death rate (ASDR) of breast cancer is predicted to increase by 7.0% from 9.20/100,000 (95% CI: 6.04–12.12) in 1990 to 9.88/100,000 (95% CI: 7.12–11.4) in 2030 in East Asia, and about 35% increase from 13.4/100,000 (95% CI: 9.21–16.02) in 1990 to 18.1/100,000 (95% CI: 13.23–21.10) in 2030 in South Asia. At the national level, the highest percent change in ASDR between 1990 and 2030 was reported in Pakistan (a 62% increase) and Nepal (a 47% increase). The highest percent change in breast cancer mortality between 2020 and 2030 for females of age group 80–84 years was observed in Pakistan [21.6, (95% CI, 20.6–94.7)], followed by Afghanistan [13.3 (4.0–80.8)], and Nepal [36.6 (11.1–125.7)] as compared to the other countries. In the females of aged 50–80 years, the predicted death rates were associated with high body mass index, high-fasting plasma glucose, and diet high in red meat, across the majority of countries under study. Furthermore, reductions in percent change in mortality rates occurred in several countries with increases in sociodemographic index (SDI), notably across high SDI countries.ConclusionBreast cancer mortality risk varies substantially across East and South Asian countries with higher mortality risk in low/middle SDI countries. Early detection using screening, awareness among females and health workers, and cost-effective and timely treatment of patients with breast cancer is vital in stemming the tide of breast cancer in the next decade.