bluuebunny/crossref_metadata_2025_split huggingface dataset:
mHealth Interventions to Reduce Physical Inactivity and Sedentary Behavior in Children and Adolescents: Systematic Review and Meta-analysis of Randomized Controlled Trials
Authors: Baumann Hannes , Fiedler Janis , Wunsch Kathrin , Woll Alexander , Wollesen Bettina 
Published: March 2022

Background
Children and adolescents increasingly do not meet physical activity (PA) recommendations. Hence, insufficient PA (IPA) and sedentary behavior (SB) among children and adolescents are relevant behavior change domains for using individualized mobile health (mHealth) interventions.

Objective
This review and meta-analysis investigated the effectiveness of mHealth interventions on IPA and SB, with a special focus on the age and level of individualization.

Methods
PubMed, Scopus, Web of Science, SPORTDiscus, and Cochrane Library were searched for randomized controlled trials published between January 2000 and March 2021. mHealth interventions for primary prevention in children and adolescents addressing behavior change related to IPA and SB were included. Included studies were compared for content characteristics and methodological quality and summarized narratively. In addition, a meta-analysis with a subsequent exploratory meta-regression examining the moderating effects of age and individualization on overall effectiveness was performed.

Results
On the basis of the inclusion criteria, 1.3% (11/828) of the preliminary identified studies were included in the qualitative synthesis, and 1.2% (10/828) were included in the meta-analysis. Trials included a total of 1515 participants (mean age (11.69, SD 0.788 years; 65% male and 35% female) self-reported (3/11, 27%) or device-measured (8/11, 73%) health data on the duration of SB and IPA for an average of 9.3 (SD 5.6) weeks. Studies with high levels of individualization significantly decreased insufficient PA levels (Cohen d=0.33; 95% CI 0.08-0.58; Z=2.55; P=.01), whereas those with low levels of individualization (Cohen d=−0.06; 95% CI −0.32 to 0.20; Z=0.48; P=.63) or targeting SB (Cohen d=−0.11; 95% CI −0.01 to 0.23; Z=1.73; P=.08) indicated no overall significant effect. The heterogeneity of the studies was moderate to low, and significant subgroup differences were found between trials with high and low levels of individualization (χ21=4.0; P=.04; I2=75.2%). Age as a moderator variable showed a small effect; however, the results were not significant, which might have been because of being underpowered.

Conclusions
Evidence suggests that mHealth interventions for children and adolescents can foster moderate reductions in IPA but not SB. Moreover, individualized mHealth interventions to reduce IPA seem to be more effective for adolescents than for children. Although, to date, only a few mHealth studies have addressed inactive and sedentary young people, and their quality of evidence is moderate, these findings indicate the relevance of individualization on the one hand and the difficulties in reducing SB using mHealth interventions on the other.

Trial Registration
PROSPERO CRD42020209417; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=209417
SGLT2 Inhibition and Uric Acid Excretion in Patients with Type 2 Diabetes and Normal Kidney Function
Authors: Suijk Danii L.S. , van Baar Michaël J.B. , van Bommel Erik J.M. , Iqbal Zainab , Krebber Merle M. , Vallon Volker , Touw Daan , Hoorn Ewout J. , Nieuwdorp Max , Kramer Mark M.H. , Joles Jaap A. , Bjornstad Petter , van Raalte Daniël H. 
Published: March 2022

Background and objectives
Sodium-glucose transporter 2 (SGLT2) inhibitor–induced uric acid lowering may contribute to kidney-protective effects of the drug class in people with type 2 diabetes. This study investigates mechanisms of plasma uric acid lowering by SGLT2 inhibitors in people with type 2 diabetes with a focus on urate transporter 1.

Design, setting, participants, & measurements
We conducted an analysis of two randomized clinical trials. First, in the Renoprotective Effects of Dapagliflozin in Type 2 Diabetes study, 44 people with type 2 diabetes were randomized to dapagliflozin or gliclazide for 12 weeks. Plasma uric acid, fractional uric acid excretion, and hemodynamic kidney function were measured in the fasted state and during clamped euglycemia or hyperglycemia. Second, in the Uric Acid Excretion study, ten people with type 2 diabetes received 1 week of empagliflozin, urate transporter 1 blocker benzbromarone, or their combination in a crossover design, and effects on plasma uric acid, fractional uric acid excretion, and 24-hour uric acid excretion were measured.

Results
In the Renoprotective Effects of Dapagliflozin in Type 2 Diabetes study, compared with the fasted state (5.3±1.1 mg/dl), acute hyperinsulinemia and hyperglycemia significantly reduced plasma uric acid by 0.2±0.3 and 0.4±0.3 mg/dl (both P<0.001) while increasing fractional uric acid excretion (by 3.2%±3.1% and 8.9%±4.5%, respectively; both P<0.001). Dapagliflozin reduced plasma uric acid by 0.8±0.8 during fasting, 1.0±1.0 in hyperinsulinemic-euglycemic state, and 0.8±0.7 mg/dl during hyperglycemic conditions (P<0.001), respectively, whereas fractional uric acid excretion in 24-hour urine increased by 3.0%±2.1% (P<0.001) and 2.6%±4.5% during hyperinsulinemic-euglycemic conditions (P=0.003). Fractional uric acid excretion strongly correlated to fractional glucose excretion (r=0.35; P=0.02). In the Uric Acid Excretion study, empagliflozin and benzbromarone both significantly reduced plasma uric acid and increased fractional uric acid excretion. Effects of combination therapy did not differ from benzbromarone monotherapy.

Conclusions
In conclusion, SGLT2 inhibitors induce uric acid excretion, which is strongly linked to urinary glucose excretion and is attenuated during concomitant pharmacologic blockade of urate transporter 1.

Clinical Trial registry name and registration number:
Renoprotective Effects of Dapagliflozin in Type 2 Diabetes (RED), NCT02682563; SGLT2 Inhibition: Uric Acid Excretion Study (UREX), NCT05210517
Public procurement in construction: international practice
Authors: Gusakova Elena A. , Pavlov Alexander S. 
Published: March 2022

Introduction. The distribution and receipt of design and construction orders is a most important element in the construction life cycle. It is of considerable interest to study the rules governing the distribution of state orders and the practice of their application in various countries. This article examines the experience of the leading world economies accumulated in the bidding for construction projects.
Materials and methods. The authors studied original legal documents on the organization of tenders for construction works in several countries, as well as in international organizations. The tender rules of the USA, France, Germany, New Zealand, Japan, China are considered. Materials of reviews and scientific researches, conducted by other scientists, are also used and summarized.
Results. The principal methods for organizing tenders for construction and design works were identified as a result of analysis of regulatory documents. The authors have found many common approaches and methods used to assure equal and responsible relations between the state customer and the construction contractor.
Conclusions. It has been established that a number of methods, widely used abroad, are practically not used in Russia, for example, competitive negotiations and two stage tendering. On the contrary, a foreign reader may think that some provisions of the Russian legislation are strange, for example, initial contract price setting by the customer or electronic document management rules in the federal law.
DEKONSTRUKSI KUASA PATRIARKI NOVEL RARA MENDUT KARYA Y.B. MANGUNWIJAYA: PERSPEKTIF FEMINISME EKSISTENSIALIS
Authors: Indra Andi Batara , Sabaruddin Sabaruddin , Darussalam Fajrul Ilmy , Ilham M , Agustan Agustan 
Published: March 2022

Abstrak: Penelitian ini bertujuan untuk memberikan informasi terkait kedudukan perempuan dalam novel “Rara Mendut” karya Y.B. Mangunwijaya serta menunjukkan bentuk dekonstruksi melalui perspektif feminisme eksistensialis Simone de Beauvoir terhadap kuasa patriarki. Penelitian ini adalah penelitian kualitatif deskriptif yang memiliki data yang berupa teks yang terdapat di dalam novel “Rara Mendut”. Hasil dalam penelitian ini menunjukkan bahwa Novel “Rara Mendut” Karya Y.B Mangunwijaya menunjukkan wujud kuasa patriarki yang melekat di dalam masyarakat, serta menunjukkan dekonstruksi kuasa patriarki melalui feminisme eksistensialis dalam bentuk penolakan dan perlawanan.Kata Kunci: kuasa, patriarki, feminism eksistensialis Abstract: This study aims to provide information related to the position of women in the novel "Rara Mendut" by Y.B. Mangunwijaya and show a form of deconstruction through the perspective of Simone de Beauvoir's existentialist feminism towards patriarchal power. This research is a descriptive qualitative research which has data in the form of text contained in the novel "Rara Mendut". The results in this study indicate that the novel "Rara Mendut" by Y.B Mangunwijaya shown a form of patriarchal power inherent in society, also the deconstruction of patriarchal power through existentialist feminism in the form of rejection and resistance.Keywords: power, patriarchy, existentialist feminism
Contemporaneous Emotion Regulation Theoretical Models: A Systematic Review
Authors: Cremades Camila Florencia , Garay Cristian Javier , Etchevers Martín Juan , Muiños Roberto , Peker Graciela Mónica , Gómez Penedo Juan Martín 
Published: March 2022

Background: Emotions and their regulation are a phenomenon present in everyday life. Despite its relevance and growing interest, a consensual and univocal definition has not yet been reached. Objective: This paper aims to review contemporary theoretical models of emotion regulation, looking for agreements and divergences between authors. It seeks to identify the main processes considered when working with emotional dysregulation. Method: Our team conducted a systematic review in the form of a narrative synthesis following the guidelines of the PRISMA statement. The database used were SCOPUS, PUBMED, and Dialnet. We included articles published between 2018 and 2020, which have been peer-reviewed in indexed scientific journals, whose central theme was the theoretical presentation of the construct of emotional regulation. We excluded articles that conceptualized only one dimension of the construct focused on specific populations and empirical studies without a theoretical conceptualization of the construct. The information was systematized in a table identifying authors' information, country of institutional affiliation, main characteristics of the given definition of emotion regulation, regulation skills mentioned, and underlying theoretical frameworks. Results: We identified ten different theoretical frameworks that propose models of emotion regulation. The main components found in the definition were the complexity of the construct, goal orientation, intra- or interpersonal regulation, the proposal of moderators, and its voluntary character. Discussion: There is a consensus on the use of emotion regulation strategies to adapt to environmental demands, achieve goals and increase well-being. We identify that people's learning history is an important factor in the development of emotional regulation skills. In addition, context and personality traits are proposed as moderators of the therapeutic efficacy of interventions focused on emotional regulation. Further studies along these lines would favor the implementation of preventive interventions and the personalization of treatments.
Structural and functional characteristics of phytoplankton of Lake Vendyurskoe affected by trout farm
Authors: Slastina Yuliya , Zdorovennova Galina Eduardovna , Smirnova Valeria Sergeevna 
Published: March 2022

The paper presents the results of a study of the phytoplankton of small Lake Vendyurskoe (south of Karelia) in the spring ice period, in summer and autumn seasons of 2020. The dynamics of quantitative and structural indices of lake algae during the trout farm operation is considered in comparison with the indices of previous years. For the studied seasons of 2020 there were identified 122 taxa of algal flora belonging to 8 divisions. The structure of algocenoses can be characterized by rich species diversity and quantitative development as diatom green structure with golden algae insertions. In autumn the representatives of cyanobacteria were encountered en masse in some areas. Phytoplankton abundance in the spring ice period varied within 612 thousand cells/l - 2188 thousand cells/l, the biomass reached 2.9 mg/l with a minimum value of 0.1 mg/l. Phytoplankton abundance for the studied summer period of 2020 averaged 2216±796 thousand cells/l with a maximum value of 3986 thousand cells/l, the average biomass in the lake did not ex-ceed 1.325±0.504 mg/l. Phytoplankton abundance in autumn averaged 4934±1665 thousand cells/l with a maximum value of 7832 thousand cells/l; biomass averaged 5.8±1.5 mg/l with a maximum value of 7.9 mg/l. According to the eco-logical and geographical characteristics, most representatives of the algal flora found in the lake are widespread freshwater organisms belonging to the planktonic flora and preferring a neutral reaction of the environment. The Shannon index increased from 2.8 in the center of the lake to 3.3 in the trout farming area, which indicates good species diversity. The Sorensen index of 0.8 revealed the homogeneity between phytoplankton communities in different areas of the lake. Most of the identified types of saprobity indices belong to the representatives of the
β-mesosaprobic and oligo-beta-mesosaprobic zones (up to 78% of the total number of identified indicator species). The saprobity index corresponded to the 2nd class of water purity (pure, α-oligosaprobic), which is due to the species composition of the dominant phytoplankton complex, however, the biomass indicates that the lake belongs to the 3rd class of water purity (satisfactorily clean, β-mesosaprobic).
Espectadores de cine en la obra de Woody Allen
Authors: Casado Pérez Francisco 
Published: March 2022

El cine de Woody Allen siempre ha prestado especial predilección por el ritual de la sala cinematográfica y por cómo los espectadores que a ella acuden valoran y sienten las películas que ven. El propio Woody Allen es un espectador más de las obras de otros artistas, mostrando en muchas ocasiones su veneración por ellos. Pero desde su punto de vista como creador, a lo largo de su obra, sitúa a sus personajes como espectadores en cines, museos y teatros, así como lectores de grandes obras de la literatura universal. Así, se vislumbra cómo los personajes no-artistas hacen uso de manifestaciones como el cine, la música y la radio, desde su condición de meros espectadores que usan el arte como evasión, prefiriendo en algunos casos este a la vida. Mediante el análisis centrado en los personajes de Recuerdos (Allen, 1980), La rosa púrpura del Cairo (Allen, 1985) y Días de radio (Allen, 1987) se contemplarán varios tipos de espectadores dentro de la obra del director neoyorquino: estos amalgaman las diferentes miradas que se pueden apreciar a la hora de enfrentarse a una pantalla de cine, a la obra que se disfruta y al artista que la realiza. En una época, la actual, en la que la sala de cine está perdiendo su aura en beneficio de opciones más caseras, resulta de interés observar de qué modo, entre la amargura y la nostalgia, aparecen reflejadas las miradas de varios espectadores de ficción.
Association Between ESR1 XBAI and Breast Cancer Susceptibility: A Systematic Review and Meta-Analysis
Authors: Sunemail Tongyou , Lian Rui , Liang Xiujun , Sun Dayong 
Published: March 2022

Purpose: Estrogen receptor 1 (ESR1) XbaI polymorphisms may affect breast cancer susceptibility; however, the results of previously published studies are inconsistent. This meta-analysis aimed to investigate the relationship between ESR1 XbaI polymorphism and breast cancer risk.
Methods: Articles from the PubMed, Embase, Cochrane Library, WoS, Scopus, Wanfang Data, CNKI, CBM and CQVIP databases were systematically searched to determine the association between ESR1 XbaI polymorphism and breast cancer risk. The pooled results were assessed using odds ratios (ORs) and 95% confidence intervals (CIs), followed by subgroup analysis.
Results: Twenty-two studies involving 12,821 cases and 14,739 control subjects were analyzed. The pooled results indicated that ESR1 XbaI polymorphism may decrease risk of breast cancer in AG vs. AA (co-dominant model: OR = 0.88, 95% CI = 0.79–0.97, P = 0.015) and AG + GG vs. AA models (dominant model: OR = 0.89, 95% CI = 0.80–0.98, P = 0.022). Subgroup analysis indicated significant associations between the ESR1 XbaI polymorphism and breast cancer risk were observed in Asian subjects, non-Hardy-Weinberg equilibrium study, post-menopausal status and hospital-based subgroups under the AG vs. AA and AG + GG vs. AA models (all P < 0.05).
Conclusions: Our analysis of pooled data indicated that AG genotype in ESR1 XbaI may be a protective factor for breast cancer patients in some subgroups.
Long Term Prognostic Value Of SYNTAX Score II Among Stemi Patients—A Comprehensive Result From Meta-Analysis
Authors: Yu Changjie , Xie Qianying , Cai Lei , Chen Zexin , Qiu Sheng 
Published: March 2022

Purpose: To assess the predictive value of SS II (SYNTAX score II) for long-term outcomes in ST-elevated myoarial infarction (STEMI) patients.
Source: PubMed, EMBASE and Cochrane databases were searched up until September 24, 2021. Two investigators extracted data independently from the relevant articles. A random-effects model was conducted to combine the pooled hazard ratio (HR) or risk ratio (RR) for association between SS II and long term outcomes.
Principal findings: A total of 12 articles (7,195 subjects) were included in the final meta-analyses. Analysis of nine of the articles showed that higher SS II predicted poor long term all-cause mortality among STEMI patients (pooled RRs=4.09,95%CI: 3.49-4.80). A similar association of SS II with poor long term mortality was observed when the crude HRs and adjusted HRs were pooled (crude HRs: pooled HR=1.07, 95%CI: 1.04-1.09; adjusted HRs: pooled HR=1.05, 95%CI:1.04-1.07). The STEMI patients with higher SS II also showed a higher associated with increased risk of long term major adverse cardiac events (pooled HR = 1.05, 95% CI: 1.02-1.07; pooled RR=2.28, 95%CI:2.02-2.57). A consistent association was found for heart failure among STEMI patients.
Conclusion: Higher SS II predicted poor long term all-cause mortality, major adverse cardia events and heart failure among STEMI patients
ANALYSIS OF MORBIDITY AND MORTALITY FROM MALIGNANT NEOPLASMS OF THE LARYNX IN UKRAINE AND LVIV REGION IN 2010-2019 YEARS
Authors: Gutor Taras , Litvinyak Ruslan 
Published: March 2022

Aim. Analysis of the epidemiological block of the model of early detection and prevention of laryngeal malignancies.
Material and Methods. A retrospective analysis of morbidity and mortality from malignant neoplasms of the larynx among the population of Ukraine and Lviv region for ten years (from 2010 to 2019). Statistical data of the National Cancer Registry of Ukraine were used. The following methods are used in the work: medical-statistical analysis, system approach, and structural-logical analysis.
Results and Discussion. The primary incidence of laryngeal cancer among the population of Ukraine decreased by 6% (from 5 cases per 100,000 population in 2010 to 4.7 cases per 100,000 population in 2019). In Lviv region, there was an increase in the level of primary morbidity by 12.3% (from 5.7 cases per 100,000 population in 2010 to 6.4 cases per 100,000 population in 2019). In 2010-2019, the mortality rates from laryngeal cancer in Ukraine and Lviv region were in the range of 2.7-3.1 and 2.8-4.6 cases per 100,000 population, respectively. The proportion of men with newly diagnosed laryngeal cancer was 94.4-95.8%, and women - only 4.2-5.6%. Analysis of sex and age incidence of laryngeal cancer in Ukraine in 2019 showed that the highest rates among both men and women were in the age group of 60-74 years. The proportion of patients with stage IV laryngeal cancer in Ukraine in 2010 and 2019 was 10.2% and 15%, respectively. A similar indicator in the Lviv region in 2010 was 12.6%, and in 2019 - 20.8%. Mortality up to one year from among newly diagnosed patients in 2019 in Ukraine was 25.1%, and in Lviv region - 23%. In Ukraine in 2019, the proportion of patients detected at professional examinations was 11.2%, in Lviv region - only 0.7%.
Conclusion. The incidence of malignant neoplasms of the larynx among the population of Lviv region during the study period was higher than the national. There was a tendency to reduce the death rate from laryngeal cancer in both Ukraine and Lviv region. In men, laryngeal cancer is more common than in women in Ukraine and the Lviv region. The incidence of malignant neoplasms of the larynx is highest among people 60 years and older. There was a low proportion of patients identified during preventive examinations, as well as high mortality rates up to one year from diagnosis and neglect of the malignant process.
TANGGUNG JAWAB PERUSAHAAN INDUK LION GROUP TERHADAP PRAKTIK DISKRIMINASI PENJUALAN KAPASITAS KARGO
Authors: Bianca Zahara Siti , Pringgodani Sanusi Heru 
Published: March 2022

KPPU memutus Lion Air, Batik Air, Wings Air, dan Lion Parcel (Lion Group Airlines), melalui perjanjian tertutup telah melakukan praktik diskriminasi terhadap Perusahaan Jasa Titipan (PJT) di Pasar-pasar Geografis tertentu. Rumusan masalah yang Penulis bahas ialah bagaimana pertanggung jawaban PT. Langit Esa Oktagon dan PT. Lion Group sebagai Perusahaan Induk terhadap perjanjian tertutup oleh Lion Group Airlines sebagai Anak Perusahaan yang terindikasi sebagai praktik diskriminasi dan Bagaimana bentuk tanggung jawab yang dapat diberikan oleh PT. Langit Esa Oktagon dan PT. Lion Group sebagai Perusahaan Induk. Metode yang digunakan penulis ialah normatif, sifat penulisan deskriptif, jenis data menggunakan data primer dan sekunder, analisis data secara kualitatif, serta pengambilan kesimpulan dengan logika deduktif. Berdasarkan hasil kajian UUPT, UU Anti Monopoli, dan Peraturan-peraturan terkait lainnya, maka kepada para pelaku usaha dapat diaplikasikan doktrin Single Economy Entity (SEE) yang menganggap satu Perusahaan Grup sebagai suatu kesatuan entitas ekonomi sehingga terjadi pertanggung jawaban renteng antar perusahaan di dalamnya, sehingga dalam kasus tersebut PT. Langit Esa Oktagon dan PT. Lion Group dapat dikenakan sanksi pidana berdasarkan peraturan perundang-undangan yang berlaku, dalam hal ini ialah UU No.5 Tahun 1999 tentang Larangan Praktik Monopoli dan Persaingan Usaha Tidak Sehat