bluuebunny/crossref_metadata_2025_split huggingface dataset:
Management of Rib Avascular Necrosis Complicated by Osteomyelitis in a Patient With Sickle Cell Anemia
Authors: Albalkhi Ibrahem , Saleh Tariq , Khan Jibran , Saleh Waleed 
Published: December 2022

Abstract

Introduction
Avascular necrosis of the rib is a rare presentation of sickle cell anemia's vaso-occlusive crisis. This report describes the case of a 45-year-old man known to have sickle cell anemia presenting with rib avascular necrosis complicated by osteomyelitis. The patient came to the outpatient department with left lateral chest wall pain. Antibiotics produced no improvement. A computed tomography scan of the chest revealed a left sixth rib fracture with a thick fluid collection consistent with pus. The patient was taken to surgery and underwent necrotic bone debridement and pus drainage. The patient showed improvement and became afebrile after the surgery.

Conclusion
The lack of distinct clinical indicators and low occurrence of rib avascular necrosis can lead to misdiagnosis and mismanagement of the disease.
Recent Therapeutic Advances in Pituitary Carcinoma
Authors: Robertson Ian J. , Gregory Timothy A. , Waguespack Steven G. , Penas-Prado Marta , Majd Nazanin K. 
Published: December 2022

ABSTRACT
Pituitary carcinoma (PC) is a rare, aggressive malignancy that comprises 0.1–0.2% of all pituitary tumors. PC is defined anatomically as a pituitary tumor that metastasizes outside the primary intrasellar location as noncontiguous lesions in the central nervous system or as metastases to other organs. Similar to pituitary adenoma, PC originates from various cell types of the pituitary gland and can be functioning or nonfunctioning, with the former constituting the majority of the cases. Compression of intricate skull-based structures, excessive hormonal secretion, impaired pituitary function from therapy, and systemic metastases lead to debilitating symptoms and a poor survival outcome in most cases. PC frequently recurs despite multimodality treatments, including surgical resection, radiotherapy, and biochemical and cytotoxic treatments. There is an unmet need to better understand the pathogenesis and molecular characterization of PC to improve therapeutic strategies. As our understanding of the role of signaling pathways in the tumorigenesis of and malignant transformation of PC evolves, efforts have focused on targeted therapy. In addition, recent advances in the use of immune checkpoint inhibitors to treat various solid cancers have led to an interest in exploring the role of immunotherapy for the treatment of aggressive refractory pituitary tumors. Here, we review our current understanding of the pathogenesis, molecular characterization, and treatment of PC. Particular attention is given to emerging treatment options, including targeted therapy, immunotherapy, and peptide receptor radionuclide therapy.
DIFERENCIAÇÃO TERRITORIAL E URBANODIVERSIDADE
Authors: Cordeiro da Trindade Júnior Saint-Clair 
Published: December 2022

A presente reflexão busca discutir a diversidade territorial e urbana brasileira como pressuposto para pensar teorias e políticas urbanas em nível nacional. Para isso, considera-se o atributo da diversidade, recorrentemente sugerido como elemento importante para compreender a sociedade, como igualmenteválido para tratar diferenças espaciais brasileiras e a manifestação não homogênea do fenômeno urbano em nível nacional. Nesse sentido, utiliza-se o termo urbanodiversidade como sugestivo para dois tipos de empreendimentos: o primeiro, no campo do pensamento teórico, e o segundo, no campo da ação política. Para esse intento de reflexão, inicialmente são feitas algumas considerações a respeito da pertinência do atributo da diversidade para abordar questões atuais no âmbito da ciência geográfica e, em seguida, visualiza-se esse mesmo atributo para enfocar a particularidade regional e urbana amazônica. Finaliza-se apresentando elementos caracterizadores da particularidade urbana da Amazônia e que buscam anunciar a urbanodiversidade que se faz presente nessa mesma realidade regional.
PENINGKATAN PRESTASI SISWA SMK TEKNIKOM CIKARANG MELALUI PEMANFAATAN INTERNET DI ERA INDUSTRI 4.0
Authors: Ahmad Fauzi  , Sutan Faisal  , Amril Mutoi  
Published: December 2022

SMK Teknikom Cikarang merupakan sekolah kejuruan di kabupaten Bekasi pada bidang teknik pemesinan, teknik pengendalian produksi, teknik kendaraan ringan, teknik komputer dan jaringan, dan multimedia. Letaknya yang berada pada Kawasan industri potensial menuntut lulusan yang memiliki keahlian sesuai kebutuhan industri pada era industri 4.0. Para siswa perlu diberikan motivasi, pengetahuan dan keahlian dalam pemanfaatan internet untuk meningkatkan potensi yang dimiliki. Internet merupakan teknologi yang menyediakan berbagai data dan informasi dari penulis atau pengisi konten mengenai topik tertentu. Melalui pelatihan pemanfaatan internet untuk siswa SMK Teknikom Cikarang, siswa dapat menggunakan internet secara sehat, mendapatkan data dengan pencarian melalui key yang tepat, memanfaatkan Google Applications dengan lebih baik. Hal tersebut menunjang peningkatan prestasi siswa dalam pembelajaran di sekolah maupun peran di masyarakat.
Kata kunci—era industri, internet, prestasi siswa
SMK Teknikom Cikarang is a vocational school in Bekasi district in the fields of engineering, production control techniques, light vehicle engineering, computer and network engineering, and multimedia. Its location in a potential industrial area demands graduates who have skills according to industrial needs in the industrial era 4.0. Students need to be given motivation, knowledge and skill in using the internet to increase their potential. Internet is a technology that provides various data and information from writers or content fillers on certain topics. Through internet use training for SMK Teknikom Cikarang students, students can use the internet healthily, get data by searching through the right key, make better use of Google Applications . This supports the improvement of student achievement in learning at school and the role in society.
Keywords—industrial era, internet, student achievement
Analisis Bisnis Vtube Perspektif Hukum Islam
Authors: Barakah Ainun 
Published: December 2022

Bisnis di era modern ini sangat beragam, sehingga sistem yang digunakan dalam dunia bisnis juga beragam, baik dalam sistem penjualan maupun sistem pemasaran, sehingga perlu untuk analisis bisnis untuk mengetahui hukum suatu bisnis menurut hukum Islam.
Permasalahan yang dikaji dalam penelitian ini adalah analisis bisnis Vtube perspektif hukum Islam. Masalah tersebut diuraikan dalam beberapa fokus penelitian berikut: 1) bagaimana sistem kerja bisnis Vtube. 2) Bagaimana hukum bisnis Vtube perspektif hukum Islam. Penelitian ini bertujuan untuk (1) mengetahui sistemkerja bisnis Vtube. (2) mengetahui hukum binsis Vtube perspektif hukum Islam.
Metode penelitian yang digunakan dalam peneltian ini adalah metode kualitatif, sedangkan teknik pengumpulan data yang digunakan adalah teknik observasi, interview mendalam dan dokumentasi. Teknik analisis data yang digunakan adalah editing, koding dan sistemazing. Teknik pengecekan keabsahan data menggunakan perpanjangan pengamatan, trianggulasi, dan meningkatkan ketekunan.
Hasil dari penelitian ini menyatakan bahwa 1) sistem kerja yang digunakan dalam bisnis Vtube meliputi 3 sistem yaitu, personal point, referral point dan group point. 2) hukum bisnis Vtube perspektif hukum Islam adalah tidak boleh karena tidak memenuhi syarat yang telah ditetapkan dalam fatwa DSN MUI tentang penjualan langsung berjenjang syariah (PLBS), dan Vtube juga termasuk bisnis Ilegal yang dihentikan oleh satgas waspada Investasi.
Moonraker: Enceladus Multiple Flyby Mission
Authors: Mousis O. , Bouquet A. , Langevin Y. , André N. , Boithias H. , Durry G. , Faye F. , Hartogh P. , Helbert J. , Iess L. , Kempf S. , Masters A. , Postberg F. , Renard J.-B. , Vernazza P. , Vorburger A. , Wurz P. , Atkinson D. H. , Barabash S. , Berthomier M. , Brucato J. , Cable M. , Carter J. , Cazaux S. , Coustenis A. , Danger G. , Dehant V. , Fornaro T. , Garnier P. , Gautier T. , Groussin O. , Hadid L. Z. , Ize J.-C. , Kolmasova I. , Lebreton J.-P. , Maistre S. Le , Lellouch E. , Lunine J. I. , Mandt K. E. , Martins Z. , Mimoun D. , Nenon Q. , Caro G. M. Muñoz , Rannou P. , Rauer H. , Schmitt-Kopplin P. , Schneeberger A. , Simons M. , Stephan K. , Hoolst T. Van , Vaverka J. , Wieser M. , Wörner L. 
Published: December 2022

Abstract
Enceladus, an icy moon of Saturn, possesses an internal water ocean and jets expelling ocean material into space. Cassini investigations indicated that the subsurface ocean could be a habitable environment having a complex interaction with the rocky core. Further investigation of the composition of the plume formed by the jets is necessary to fully understand the ocean, its potential habitability, and what it tells us about Enceladus’s origin. Moonraker has been proposed as an ESA M-class mission designed to orbit Saturn and perform multiple flybys of Enceladus, focusing on traversals of the plume. The proposed Moonraker mission consists of an ESA-provided platform with strong heritage from JUICE and Mars Sample Return and carrying a suite of instruments dedicated to plume and surface analysis. The nominal Moonraker mission has a duration of ∼13.5 yr. It includes a 23-flyby segment with 189 days allocated for the science phase and can be expanded with additional segments if resources allow. The mission concept consists of investigating (i) the habitability conditions of present-day Enceladus and its internal ocean, (ii) the mechanisms at play for the communication between the internal ocean and the surface of the South Polar Terrain, and (iii) the formation conditions of the moon. Moonraker, thanks to state-of-the-art instruments representing a significant improvement over Cassini's payload, would quantify the abundance of key species in the plume, isotopic ratios, and the physical parameters of the plume and the surface. Such a mission would pave the way for a possible future landed mission.
Expressivité, exclamation et ponctuation
Authors: Bikialo Stéphane , Rault Julien 
Published: December 2022

L’article appréhende l’expressivité à travers une forme de réalisation archétypale : l’exclamation et son représentant graphique, le point d’exclamation. La description de la présence énonciatrice et de l’effet sur le récepteur, ainsi que le rapport entre croissance ou décroissance verbale dans les formes exclamatives, permettent d’interroger l’expressivité en termes d’historicité mais aussi de distinguer expressivité et impressivité et, enfin, d’examiner la dimension non verbale autour de la question de l’inscription du corps dans l’écrit. À partir de ces rappels et analyses, l’article s’interroge – de manière plus théorique – sur les rapports entre subjectivité, expressivité/impressivité et modalité. Pour ce faire, les auteurs prennent appui sur ce qui a été décrit comme un style non expressif, neutre (« l’écriture plate » de Ernaux, décrite dans une formule très ballyenne comme une manière de rester ancrée dans « la langue de tous »).
La « bonne mesure » de l’expression de la féminité et de la masculinité au sein de l’institution scolaire en Martinique(2015-2016)
Authors: Tondellier Michel 
Published: December 2022

Cet article est consacré à une forme peu étudiée des rapports de pouvoir qui s’observent au sein des communautés éducatives : le contrôle des élèves par la régulation de leurs tenues vestimentaires. Les traces écrites de ces rapports de pouvoir définissent parfois avec moult précisions les tenues vestimentaires à respecter dans l’enceinte des établissements scolaires. Nous établirons que les interdits nous renseignent sur les stéréotypes de genre qui animent les communautés éducatives permettant de distinguer les « bons » des « mauvais » élèves en encourageant l’adhésion à des formes de masculinité et de féminité très mesurées. Cette réalité sociale posée, nous tâcherons dans un deuxième temps, d’une part de clarifier les mécanismes d’exclusion des élèves non conformes et, d’autre part, d’éclairer les éléments concourant à l’ancrage socio-historique de ces formes de masculinités et féminités désirables, complices, subordonnées ou marginalisées. Quels facteurs à la fois historiques, économiques, sociaux et culturels favorisent cette structure sociale genrée propre aux régions françaises des Antilles ?
L’éducation coloniale au prisme de l’intersectionnalité(Antilles françaises, 1795-1830)
Authors: Fayolle Caroline 
Published: December 2022

Les écoles instaurées dans les colonies antillaises françaises durant les périodes révolutionnaire et postrévolutionnaire ont été peu étudiées par l’historiographie. Cette contribution se propose de les mettre en lumière et de les analyser par le prisme du concept d’intersectionnalité. Elle s’organise autour de deux axes. Le premier axe est centré sur la question de la mixité (raciale et sexuelle) dans les écoles coloniales instaurées par le Directoire suite à la première abolition de l’esclavage. Le second axe s’intéresse à la reconstruction du système scolaire après 1802, année du rétablissement de l’esclavage. Dans un contexte où des savants au service du pouvoir remettent en cause la capacité des hommes noirs et des femmes à être perfectionnés par l’instruction, l’étude de ces écoles éclaire l’imbrication des rapports de domination de sexe, de race et de classe au sein des sociétés coloniales antillaises.
Student Selection of Preceptors for Immersive Clinical Education Experiences Through an Advocacy Lens
Authors: Edler Nye Jessica R. , Viesselman Christopher P. , Eberman Lindsey E. , Winkelmann Zachary K. 
Published: December 2022

Context
Immersive clinical education is an integral component of athletic training curricula. The flexibility in the requirements allows programs to be innovative in their curricular design and to meet the needs of their learners.

Objective
The purpose of this educational technique is to describe the process for empowering students to choose preceptors and clinical sites that meet their needs.

Background
Traditionally, program administrators assign students to preceptors and clinical sites based on proximity and availability of clinicians surrounding the institution. However, this may limit the options for students to find preceptors and mentors who are best suited to prepare them for future clinical practice.

Description
In our program, we empower students to pursue their immersive clinical education experience with a preceptor and/or clinical site that will meet their personal and professional needs as a learner and future clinician.

Advantages
Preceptors and alumni have noted increased engagement when students are invested in the selection process. Students are encouraged to advocate for their needs personally and professionally, to place themselves in the best environment for their future success. More specifically, historically marginalized students have the opportunity to identify a preceptor with similar demographic characteristics, who may be better suited to mentor them as a future professional, when geographic proximity has been a challenge in the past.

Conclusions
Students and program administrators partner to select preceptors who provide opportunities for a successful immersive clinical experience, who align with the student's future career goals, and who provide mentorship. Historically marginalized students in less diverse regions may benefit the most from this model because they can overcome geographic proximity challenges to identifying effective preceptors and mentors.
Graft and patient survival in kidney transplantation: A single-center experience
Authors: Chen Chang-Hsu , Kuo Yuan-Chuan , Wu Tsai-Kun , Chen Hung-Ping , Tseng Tien-Yu , Pai Mei-An , Chien Shiaw-Wen , Lim Paik-Seong 
Published: December 2022

Background:
Patients with end-stage renal disease need renal replacement therapy, including hemodialysis, peritoneal dialysis, and kidney transplant (KT), to live a relatively normal life. Compared with other dialysis modalities, KT remains the choice for better survival.

Objectives:
This study aimed to report the KT outcomes at our center and investigate risk factors for graft and patient survival.

Methods:
This is a retrospective chart review of 72 KT recipients cared for at our center between July 1, 2004, and June 30, 2017. Delayed graft function (DGF) was defined as the need for dialysis within 1 week after KT. The primary outcome is death after KT. The secondary outcome is graft failure, which is defined as a return to dialysis while the patient is alive. Patient death with functional graft was censored during the survival analysis.

Results:
Among the patients, 17 KT recipients had primary diabetic nephropathy (23.6%) with a mean age of 47.4 ± 11.8 years. Furthermore, 13 patients returned to dialysis and 12 died during the study period, with malignancy being the leading cause of death (n = 4). The 1-, 3-, and 5-year graft survival rates were 94.3%, 90.4%, and 85.4%, respectively. The 1, 3-, and 5-year patient survival rates were 97.1%, 92.1%, and 85.7%, respectively. A total of 24 patients (33%) encountered DGF after KT. Patients with DGF had significantly poorer graft survival than those without DGF (P = 0.002 by log-rank test). Cox-proportional hazard analysis revealed that only DGF increased the risk of graft failure (hazard ratio (HR) = 6.52, 95% confidence interval (CI): 1.4629.2), and age predicted patient survival (HR = 1.09, 95% CI: 1.021.17).

Conclusion:
This study showed that patients with DGF had significantly poor graft survival. Patient’s age was the only prognostic factor for patient survival in our cohort.
Handgrip strength as a predictor of mobility in patients with end-stage renal disease on hemodialysis
Authors: Liu Wen-Chih , Chiu Li-Shu , Lim Paik Seong 
Published: December 2022

Background:The Timed Up and Go (TUG) test is commonly used to assess motor function and gait stability in the elderly, including patients with chronic kidney disease (CKD). Furthermore, the handgrip strength test is used to evaluate general muscle strength and may help identify weakness, a key element of frailty.Objectives:This study aimed to determine whether the handgrip strength test is a suitable screening tool before the TUG test because it requires less physical effort and likelihood of adverse events associated with falling during testing.Methods:A total of 120 patients with CKD on hemodialysis participated in the study. The associations or correlations among handgrip strength, TUG test, and routine nutritional biomarkers were analyzed.Results:A significant correlation was observed between handgrip strength and TUG test in all patients (R= −0.39,P= 1*10-5), even in patients with diabetic kidney disease (n= 56,R= −0.36,P= 0.0065). Interestingly, when dividing the patients into two groups according to hemoglobin A1c (HbA1c) levels (<7% vs. ≥7%), no significant differences in handgrip strength or completion time of the TUG test were observed between both groups.Conclusion:In patients on hemodialysis with decreased mobility, measuring grip strength can be a reliable marker as an initial screening to determine whether patients can exert the necessary physical effort to perform the TUG test. Furthermore, a HbA1c <7% did not provide additional benefits in terms of muscle strength and mobility to patients with diabetes on hemodialysis.
Maternal and Perinatal Outcomes of Abruptio Placenta at the Lagos University Teaching Hospital
Authors: Oluwole Ayodeji A. , Ugwu Aloy O. , Akinajo Opeyemi R. 
Published: December 2022

Background:
Abruptio placentae is a form of antepartum hemorrhage that occurs when there is a partial or complete separation of the placenta before the delivery of the fetus. In addition to vaginal bleeding, it is often associated with abdominal pain, uterine tenderness, fetal heart irregularity, and hypertonic uterine contraction. It is a significant cause of maternal and perinatal morbidity and mortality. It is therefore important to review this obstetrics emergency with a view to creating more awareness on its complications.

Objectives:
The study was aimed to determine the prevalence as well as the perinatal and maternal outcomes of abruption placentae at the Lagos University Teaching Hospital (LUTH), Nigeria.

Materials and Methods:
This was a retrospective review of records of pregnant women managed in the labor and postnatal wards of LUTH, Idi-Araba, Nigeria, over a 5-year period from January 2015 to December 2019. Relevant data retrieved were entered and analyzed using the IBM Statistical Package for Social Sciences (SPSS Statistics), version 23.

Results:
A total of 80 pregnancies were complicated with abruptio placentae giving a prevalence of 0.96% of all admissions during the study period. Several maternal complications recorded included acute renal failure (6.25%), disseminated intravascular coagulation (2.08%), postpartum anemia (37.5%), and postpartum hemorrhage (54.7%). Forty six percent (46%) of the neonates had no complication, 11.3% had early neonatal death, 20% had fresh stillbirth, and 22.5% had birth asphyxia.

Conclusion:
Abruptio placentae contributed a sizeable proportion to maternal morbidity and perinatal morbidity and mortality in the study population.
Measles Serostatus in Mothers and Their Newborns in Antioquia, Colombia: Implications for Measles Elimination
Authors: Santacruz-Sanmartin Eduardo , Hincapié-Palacio Doracelly , Ochoa-Acosta Jesús E. , Buitrago-Giraldo Seti , Ospina Marta C. 
Published: December 2022

ABSTRACT.
To describe the serostatus of measles IgG antibodies in pregnant women and newborns, placental transfer, and factors that determine being below the threshold of 150 mIU/mL, a cross-sectional study was conducted. Blood samples of 790 pregnant women at the time of delivery and 734 umbilical cord samples were analyzed from eight hospitals in the Aburrá Valley of Antioquia, Colombia. Measles IgG antibody measurement was performed with ELISA. The proportion of individuals with antibodies < 150 mIU/mL was 13.9% (95% CI: 12.2–15.8) in pregnant women and 11.1% (95% CI: 9.2–13.4) in newborns. The geometric mean of the antibody level of the pregnant women was 552 mIU/mL (95% CI: 504–605) and in the umbilical cord 662 mIU/mL (95% CI: 604–727). A positive correlation between pregnant woman and umbilical cord antibodies was found. The median ratio of measles IgG antibodies in umbilical cord/pregnant woman was 1.22 for all participants. A seroprevalence below the threshold of 150 mIU/mL was found in newborns whose mothers were born between 1983 and 1994, compared with those born before that period, when exposure to the wildtype virus was common (adjusted prevalence ratio: 3.6, 95% CI: 1.3–9.6). These findings suggest that there are gaps in measles immunity among women of childbearing age, before pregnancy. To close this immune gap and support efforts to maintain measles control, serological screening for measles antibodies should be routinely included in reproductive health and antenatal care programs to identify women without immunity who should be vaccinated before pregnancy or after delivery.