bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dismissal disagreement and discharge delays: Associations of patient–clinician plan of care agreement with discharge outcomes
Authors: Olson Emily M. , Falde Samuel D. , Wegehaupt Abigail K. , Polley Eric , Halvorsen Andrew J. , Lawson Donna K. , Ratelle John T. 
Published: August 2022

AbstractBackgroundMany hospitalized patients do not understand or agree with their clinicians about their discharge plan. However, the effect of disagreement on discharge outcomes is unknown.ObjectiveTo measure the correlation between patient‐clinician care agreement and discharge outcomes.DesignA prospective cohort study was performed from September 2019 to March 2020 (Rochester, MN, USA).Setting and ParticipantsInternal medicine patients and their primary clinician (resident, advanced practice clinician or attending) hospitalized from September 2019‐March 2020 at Mayo Clinic Hospital. Participants were independently surveyed following hospital day #3 ward rounds regarding the goals of the hospitalization and discharge planning.Main Outcome and MeasuresPatient–clinician agreement for main diagnosis, patient's main concern, and four domains of discharge planning was assessed. Readiness for hospital discharge, delayed discharge, and 30‐day readmission was measured. Then, associations between patient‐clinician agreement, delayed discharge, and 30‐day readmissions were analyzed using multivariable logistic regression.ResultsOf the 436 patients and clinicians, 17.7% completely agreed about what needs to be accomplished before dismissal, 40.8% agreed regarding discharge date, and 71.1% agreed regarding discharge location. In the multivariable model, patient–clinician agreement scores were not significantly correlated with discharge outcomes. Patient–clinician agreement on discharge location was higher for those discharged to home (81.5%) versus skilled nursing facility (48.5%) or assisted living (42.9%) (p < .0001). The agreement on the expected length of stay was highest for home‐goers (45.9%) compared to skilled nursing (32.0%) or assisted living (21.4%) (p = .004).ConclusionsPatients and their clinicians frequently disagree about when and where a patient will go after hospitalization, particularly for those discharged to a skilled nursing facility. While disagreement did not predict discharge outcomes, our findings suggest opportunities to improve effective communication and promote shared mental models regarding discharge earlier in the hospital stay.
Could red cell distribution width be used for predicting cardiac injury in neonates with COVID‐19?
Authors: Elbayiyev Sarkhan , Şimşek Gülsüm K. , Ceran Burak , Akın Mustafa Ş. , Kanmaz Kutman H. Gözde , Canpolat Fuat E. 
Published: August 2022

AbstractBackgroundCoronavirus disease 2019 (COVID‐19) can affect people of all age groups and it can occasionally cause life‐threatening clinical illnesses in immunologically immature populations, especially in newborns. High red cell distribution width (RDW) values were used as an early prognostic biomarker of some neonatal diseases. We aimed to determine the prognostic value of RDW in severe acute respiratory syndrome‐coronavirus‐2 (SARS‐CoV‐2) infected neonates.MethodsNewborns with positive SARS‐CoV‐2polymerase chainreaction (PCR) test from a nasopharyngeal swab sample, who had refractory fever (>38°C and lasting more than 24 h during hospitalization), were screened for multisystem inflammatory syndrome in newborns (MIS‐N), systemic inflammatory indexes calculated and cardiologic evaluations. Due to troponin levels (high: >45 ng/L and low: ≤45 ng/L) patients were grouped.ResultsOut of the 68 SARS‐CoV‐2 PCR‐positive newborns, 26 patients had refractory fever. Comparison of laboratory findings between the high and low‐troponin groups showed that RDW and neutrophil/lymphocyte ratio values were significantly higher in patients with high troponin levels (p = 0.022 andp = 0.030, respectively). The cut‐off values with optimal sensitivity and specificity were determined as 1.00 for neutrophil/lymphocyte ratio (p = 0.205) and 16.6 for RDW (p = 0.014). None of the patients died.ConclusionsNeonatal COVID‐19 generally has a benign prognosis, but can progress to severe disease and cases of MIS‐N are rare. RDW could be prognostic in the diagnosis and management of neonates with SARS‐CoV‐2 infection with high troponin levels.
Humoral responses after inactivated COVID‐19 vaccination in individuals with and without prior SARS‐CoV‐2 infection: A prospective cohort study
Authors: Jia Mengmeng , Wang Xinming , Gong Wensheng , Zhong Jingchuan , Leng Zhiwei , Ren Lili , Feng Luzhao , Guo Li , Gao Lidong , Liang Xian , Chen Enfu , Tang Wenge , Huang Qiangru , Zhang Qiao , Jiang Guangjiong , Zhao Shanlu , Liu Zhu , Feng Yan , Qi Li , Ma Libing , Huang Tingxuan , Yue Yong , Wang Ju , Jiang Binshan , Xu Liuhui , Wang Jianwei , Yang Weizhong , Wang Chen 
Published: August 2022

AbstractWe evaluated and compared humoral immune responses after inactivated coronavirus disease 2019 (COVID‐19) vaccination among naïve individuals, asymptomatically infected individuals, and recovered patients with varying severity. In this multicenter, prospective cohort study, blood samples from 666 participants were collected before and after 2 doses of inactivated COVID‐19 vaccination. Among 392 severe acute respiratory syndrome coronavirus 2‐naïve individuals, the seroconversion rate increased significantly from 51.8% (median antispike protein pan‐immunoglobulins [S‐Igs] titer: 0.8 U/ml) after the first dose to 96% (median S‐Igs titer: 79.5 U/ml) after the second dose. Thirty‐two percent of naïve individuals had detectable neutralizing antibodies (NAbs) against the original strain but all of them lost neutralizing activity against the Omicron variant. In 274 individuals with natural infection, humoral immunity was significantly improved after a single vaccine dose, with median S‐Igs titers of 596.7, 1176, 1086.5, and 1828 U/ml for asymptomatic infections, mild cases, moderate cases, and severe/critical cases, respectively. NAb titers also improved significantly. However, the second dose did not substantially increase antibody levels. Although a booster dose is needed for those without infection, our findings indicate that recovered patients should receive only a single dose of the vaccine, regardless of the clinical severity, until there is sufficient evidence to confirm the benefits of a second dose.
Production of single‐cycle infectious SARS‐CoV‐2 through a trans‐complemented replicon
Authors: Cheung Pak‐Hin Hinson , Ye Zi‐Wei , Lui Wai‐Yin , Ong Chon Phin , Chan Pearl , Lee Tak‐Wang Terence , Tang Tze‐Tung , Yuen Tin‐Long , Fung Sin‐Yee , Cheng Yun , Chan Ching‐Ping , Chan Chi‐Ping , Jin Dong‐Yan 
Published: August 2022

AbstractSingle‐cycle infectious virus can elicit close‐to‐natural immune response and memory. One approach to generate single‐cycle severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) is through deletion of structural genes such as spike (S) and nucleocapsid (N). Transcomplementation of the resulting ΔS or ΔN virus through enforced expression of S or N protein in the cells gives rise to a live but unproductive virus. In this study, ΔS and ΔN BAC clones were constructed and their live virions were rescued by transient expression of S and N proteins from the ancestral and the Omicron strains. ΔS and ΔN virions were visualized by transmission electron microscopy. Virion production of ΔS was more efficient than that of ΔN. The coated S protein from ΔS was delivered to infected cells in which the expression of N protein was also robust. In contrast, expression of neither S nor N was detected in ΔN‐infected cells. ΔS underwent viral RNA replication, induced type I interferon (IFN) response, but did not form plaques. Despite RNA replication in cells, ΔS infection did not produce viral progeny in culture supernatant. Interestingly, viral RNA replication was not further enhanced upon overexpression of S protein. Taken together, our work provides a versatile platform for development of single‐cycle vaccines for SARS‐CoV‐2.
The fine line between localization and cultural appropriation in personal luxury goods: An exploratory study
Authors: Lojacono Gabriella 
Published: August 2022

AbstractLuxury companies have often been exposed to criticism stemming from the use of local cultural codes. This paper investigates the meaning and risks of Cultural Appropriation (CA) in Personal Luxury Goods (PLG). Findings from the case study analysis reveal that respect, giving credit, and research based on local collaborations can help companies continue to be inspired by other cultures without running the risk of appropriation.
Antecedents of intentions to crowdfund luxury brands and projects: Evidence from French consumers
Authors: Bryson Douglas , Atwal Glyn , Crespi Roberta 
Published: August 2022

AbstractLuxury firms, including high‐end watch manufacturers, use crowdfunding as an alternative source of entrepreneurial finance. Respondents indicated that intention to crowdfund luxury brand start‐ups have both external and internal antecedents with the slight majority focusing on the extrinsic factors. The “luxury” proposition exhibits integrated motivation, which is conceptualized and personalized to the tastes of each investor.
Andean purple maize to produce extruded breakfast cereals: impact on techno‐functional properties and sensory acceptance
Authors: Salvador‐Reyes Rebeca , Sampaio Ulliana Marques , de Menezes Alves Moro Thaísa , Brito Aline Duarte Correa de , Behrens Jorge , Campelo Pedro H. , Pedrosa Silva Clerici Maria Teresa 
Published: August 2022

AbstractBACKGROUNDAndean purple maize (APM) is an ancient crop widely used as a natural coloring in traditional Peruvian cuisine. However, it has been little explored within the food industry. The present study assessed how APM impacts on techno‐functional properties and sensory acceptance of breakfast cereals. Extruded samples formulated with 100, 75, 50, and 25% APM, and complemented with yellow corn grits (YCG), were analyzed for their techno‐functional and sensory properties.RESULTSIncreases in bulk density, as well as reduction in the expantion and porosity were observated for extrudates containing ≥ 50% APM, accompanied by an increase in purple color intensity. Increase in milk absorption index, reduction in milk solubility index and decrease in cereal hardness with increase in APM were also observed. Despite this, APM extented the cereal bowl‐life. High sensory scores of overall liking (6) and color (7) were obtained for extruded formulations containing ≥ 50% APM and low values for extrudates with 25% APM. Aroma, flavor, and texture scores did not present significant differences.CONCLUSIONAPM is an ingredient with the potential to be used to produce breakfast cereals since it improves their techno‐functional characteristics and sensory acceptance, at the same time, it leads to the production of healthy, nutritious, and sustainable food. © 2022 Society of Chemical Industry.
Influence of commercial starter culture on fermentation dynamics and quality characteristics of yogurts obtained with different formulations
Authors: Vénica Claudia I. , Wolf Irma V. , Beret María V. , Bergamini Carina V. , Burns Patricia , Binetti Ana , Perotti María C. 
Published: August 2022

AbstractBACKGROUNDFour commercial starter cultures containing Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus (S1, S2, S3 and S4; S3 also contained Limosilactobacillus fermentum) were compared for fermentation, volatile flavor compounds, physicochemical parameters and microbiology, in yogurt prepared from three milk base formulations with increased protein (B1, B2 and B3).RESULTSThe fermentation patterns differed among starters, with Yoflex Mild 1.0 (S4) and SLB95 (S2) showing the longest fermentation time, depending on the formulation. At 21 days, S. thermophilus counts were similar among starters and higher than 8.52 log CFU mL−1, for all yogurts. The highest counts (6.86 log CFU mL−1) for L. delbrueckii subsp. bulgaricus was found for S2 yogurts made from whey protein hydrolysate (B3). Minor water‐holding capacity was detected for YF‐L811 (S1) yogurts. Yoflex Harmony 1.0 (S3) starter containing Lim. fermentum produced a distinctive volatile profile characterized by aldehydes with respect to yogurts prepared with S1, S2 and S4, which were characterized by ketones.CONCLUSIONResults indicate the usefulness of carrying out studies similar to the present one to select the most appropriate process conditions depending on the desired product. © 2022 Society of Chemical Industry.
Treatment algorithm and surgical outcome for primary and recurrent retroperitoneal sarcomas: A long‐term single‐center experience of 242 cases
Authors: Lv Ang , Li Ying , Li Zhong‐Wu , Mao Li‐Li , Tian Xiu‐Yun , Hao Chun‐Yi 
Published: August 2022

AbstractBackground and ObjectivesRetroperitoneal sarcomas (RPSs) are difficult to manage, rare malignant tumors. This single‐center, retrospective study aimed to analyze the treatment algorithm and outcomes of aggressive surgical treatment in patients with primary and recurrent RPS.MethodsData of 242 consecutive patients with RPS who underwent surgical treatment at the Peking University Cancer Hospital Sarcoma Center between January 2010 and February 2021 were collected and analyzed. Indications for surgery were based on the treatment algorithm.ResultsA total of 145 patients with primary RPS and 97 with recurrent RPS were included. The recurrent cohort comprised more patients with multifocal tumors than the primary cohort (64.9% vs. 15.2%). R0/R1 resection was achieved in 94.5% and 81.4% of the primary and recurrent RPS cases, respectively. Major complication rates in the primary and recurrent cohorts were 17.9% and 30.9%, respectively. During a median follow‐up of 51 months, the estimated 5‐year overall survival, local recurrence, and distant metastasis rates for patients with primary and recurrent RPS were 61.0% versus 37.1%, 47.4% versus 71.3%, and 18.4% versus 17.6%, respectively.ConclusionsAggressive surgical treatment achieved good local control and long‐term survival in patients with primary RPS, whereas the prognosis in patients with recurrence were significantly worse.
Emerging roles of plasma gelsolin in tumorigenesis and modulating the tumor microenvironment
Authors: Hsieh Chih‐Hsiung , Wang Yi‐Ching 
Published: August 2022

AbstractThe protein expression of gelsolin, an actin scavenger controlling cytoskeletal remodeling, cell morphology, differentiation, movement, and apoptosis, has been found to be significantly decreased in several pathological conditions including neurodegenerative diseases, inflammatory disorders, and cancers. Its extracellular isoform, called plasma gelsolin (pGSN), is one of the most abundant plasma proteins in the circulation, and has emerged as a novel diagnostic biomarker for early disease detection. Current evidence reveals that gelsolin can function as either an oncoprotein or a tumor suppressor depending on the carcinoma type. Interestingly, recent studies have shown that pGSN is also involved in immunomodulation, revealing the multifunctional roles of pGSN in tumor progression. In this review, we discuss the current knowledge focusing on the roles of gelsolin in inflammation and wound healing, cancers, and tumor microenvironment. Future prospects of pGSN related studies and clinical application are also addressed.
Miniaturized multiband frequency selective surface with wide frequency ratio
Authors: Mathivanan Anbuselvi , Saravanan Palani 
Published: August 2022

AbstractThis article presents the design of a novel miniaturized 2.5D frequency selective surface (FSS) for radiofrequency and microwave shielding applications is proposed. The proposed FSS is configured to offer multiple band‐stop characteristics with a wide frequency ratio. The unit cell is developed using traces that run on the top and bottom layers of the substrate with traces connected using vias. This proposed unit cell structure provides distinct operating modes at high and low frequencies. The proposed FSS unit cell has a compact geometry with a foot‐print of 0.059λo × 0.059λo where λo is the freespace wavelength. The FSS unit cell is polarization insensitive and exhibits good angular stability up to 45°. A prototype FSS is fabricated to validate the simulation results. The miniaturized FSS can be used as a shield at terrestrial frequencies and satellite frequencies making it usable for both indoor and outdoor environments.
Novel compact bandpass filter using sextuple‐mode ceramic cavity resonator
Authors: Wu Xinhui , Cao Yazi , Yuan Bo , Qi Yanzhu , Wang Gaofeng 
Published: August 2022

AbstractThis letter proposes a novel compact ceramic cavity bandpass filter with surface silver coating and air coupling apertures. It is constituted of a sextuple‐mode ceramic cavity as the main resonator, two single‐mode cavities to connect the sextuple modes transversely with source and load, and two single cavities to suppress higher harmonics. This proposed filter has the advantages of compact size, wide band, low insertion loss, high selectivity, wide spurious‐free window, as well as coplanar source and load interfaces. There are no blind holes in the filter, which is beneficial for improving the machining accuracy. One prototype filter operating at 3.5 GHz is fabricated and measured. The minimum insertion loss in the passband is 0.65 dB. The inherent spurious mode of the sextuple‐mode resonator at around 1.2fC (fC center frequency) is suppressed under −30 dB. The measured and simulated results are in good agreement.
Array‐based Fabry–Pérot cavity antenna for flat‐topped radiation pattern
Authors: Ran Xi , Wang Xiao‐Hua , Hu Yi‐Di , Wang Xi‐Yu 
Published: August 2022

AbstractIn this letter, an array‐based ray tracing model and Fabry–Pérot cavity antenna covered by frequency selective surfaces (FSS) are proposed to realize the flat‐topped radiation pattern (FTRP). Based on the array‐based model, a good FTRP can be obtained by combining the initial directivity of the feed array with the additional directivity of FSS‐type partially reflective surface. By using the proposed method, a low‐cost, lightweight, simple structure and dual‐polarization Fabry‐Pérot cavity antenna with small aperture size for FTRP is designed. From the measured results, the FTRP with more than 58° beamwidth and less than 2 dB ripple level in the frequency band of 2.4 to 2.7 GHz for indoor communication are obtained.
Egg Hatchability and Egg Thiamine Concentrations in Lake Trout from the Northern Refuge of Lake Michigan
Authors: Madenjian Charles P. , Keeler Kevin M. , Grivicich Lyle T. , Haver Paul E. , Gordon Roger R. , Tillitt Donald E. , Rinchard Jacques 
Published: August 2022

Abstract
The Northern Refuge of Lake Michigan was established in 1985 under the auspices of the Great Lakes Fishery Commission as part of an intensely managed effort to restore a self-sustaining Lake Trout Salvelinus namaycush population to the lake. Despite the stocking of millions of Lake Trout into the refuge and survival of these stocked fish to adulthood, signs of natural recruitment by Lake Trout in the refuge have been very sparse. To ascertain whether low egg viability or poor fry survival could be limiting natural recruitment by Lake Trout in the refuge, hatching rates of eggs taken from Lake Trout caught in the Northern Refuge during October 2019 were determined in the laboratory. Moreover, survival rates of the hatched-out fry were determined along with the thiamine concentrations in the fry. In addition, thiamine concentrations in eggs of ovulating Lake Trout caught in the Northern Refuge during 2019–2021 were determined. Egg hatching rate in the laboratory averaged 93%. Survival rate of Lake Trout fry up to 5 weeks after hatching averaged 97%. Mean (SE) thiamine concentrations in eggs of Lake Trout caught in 2019, 2020, and 2021 were 19.1 (3.6), 5.9 (1.3), and 6.2 (0.4) nmol/g, respectively; these levels are well above the threshold concentration of 2.3 nmol/g, above which the likelihood of experiencing mortality due to thiamine deficiency complex (TDC) is low. Thiamine concentrations in the Lake Trout fry at the end of the laboratory experiment averaged 11.2 nmol/g, and abnormal behavior in the fry was not observed. We conclude that TDC does not appear to represent a major impediment to Lake Trout rehabilitation in the Northern Refuge at present, although TDC may have contributed to the lack of detectable natural recruitment in the past.
Bird remains from ecclesiastical sites in medieval Hungary
Authors: Gál Erika 
Published: August 2022

AbstractThis comprehensive paper, based on already published avian material, provides an overview of the exploitation of birds at ecclesiastical settlements in medieval Hungary, with an outlook on other European religious establishments. Owing also to the differences in excavation methods, sample size, and measurements used during the identification of bird remains, the seven discussed ecclesiastical sites in the Carpathian Basin, which was part of the Hungarian Kingdom during the Middle Ages, showed considerable variability from this point of view. It is certain that poultry constituted the lion's share of the bird meat consumed, even in the wealthiest religious houses, such as bishopric centers. The presence of sexed specimens in some of these bone collections made it possible to distinguish between a small and a large phenotype of domestic chicken based on biometric data. However, in cases when finds were not only collected by hand but the food refuse deposit was also screened, one finds that these assemblages are both quantitatively and qualitatively more varied in terms of the presence and frequency of certain taxa including small game, suggesting the value and special role of (wild) fowl at ecclesiastical establishments. The avian remains that suggest the use of trained birds, as well as the evidence for the use and curation of crossbows, contribute to our knowledge about the hunting and fowling customs at certain religious houses.
Novel dispersant‐free disperse dyes containing polyethylene oxide moieties: Synthesis and eco‐friendly dyeing on polyethylene terephthalate fabrics
Authors: Hou Li , Gao Linbo , Qian Hongfei , Fang Shuaijun , Chen Xingliang , Song Xiyu 
Published: August 2022

AbstractTo reduce pollutant emission during dyeing process with disperse dyes, novel disperse dyes containing polyethylene oxide moieties were synthesized. The amphiphilic PEG 400 was engaged in nucleophile substitution with prepared N‐ethyl‐N‐phenylglycinoyl chloride to give coupling component containing polyethylene oxide. Diazonium salts were reacted with synthesized coupling component to obtain aimed eco‐friendly disperse dyes. Fourier transform infrared and 1H‐nuclear magnetic resonance method were used to manifest structures of synthesized dyes and their intermediates. These dyes were applied on polyethylene terephthalate (PET) fabric using traditional high temperature dyeing method under pressure. Dyeing process with and without dispersants were compared, the synthesized dyes showed no dependency on dispersants. Dyed PET fabrics using dispersant‐free methods exhibited excellent levelness, excellent washing and rubbing fastness. Quantum simulations were applied to evaluate structure–property relationship of designed dyes. The optimized geometries of designed dyes and electrostatic potential energy diagrams of molecules were simulated by density functional theory method to explain dye‐fiber interaction. The designed dispersant‐free disperse dyes exhibited no dependency on dispersants and excellent rubbing and washing fastness. Reduction of dispersants could help to eliminate environmental damage related to discharge of effluent containing dispersants.