bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of vaginal progesterone for preterm birth prevention in women with threatened labor and shortened cervix diagnosed after 24 weeks of pregnancy
Authors: Kabiri Doron , Raif Nesher Dror , Luxenbourg Danielle , Rottenstreich Amihai , Rosenbloom Joshua I. , Ezra Yosef , Yagel Simcha , Porat Shay , Romero Roberto 
Published: September 2022

AbstractObjectiveTo determine whether vaginal progesterone treatment for women with a short cervix, diagnosed after 24 weeks of pregnancy, reduces preterm birth rates.MethodsA retrospective cohort study that included women with a singleton pregnancy, threatened preterm labor, and a short cervix measured between 24+0 and 33+6 weeks. Women who received vaginal progesterone were compared with women who did not receive progesterone. The primary outcome was spontaneous preterm birth before 37 weeks of pregnancy.ResultsPatients who received vaginal progesterone had a lower rate of preterm delivery at less than 37 weeks of pregnancy (18.2% [22/121] versus 28.9% [73/253]; adjusted hazard ratio 0.50; 95% confidence interval 0.28–0.73, P = 0.001). The diagnosis‐to‐delivery interval was significantly greater in patients who received progesterone than in those who did not—median time to delivery in weeks: 8.2 (interquartile range [IQR] 6.2–9.8) versus 6.6 (4.8–8.8), (P < 0.001). The frequency of neonatal intensive care unit admission was significantly lower in patients who received progesterone than in those who did not (8.3% [10/121] versus 16.2% [41/253], P = 0.04).ConclusionsThe administration of vaginal progesterone to patients with an episode of threatened premature labor and a short cervix presenting after 24 weeks of pregnancy was associated with lower rates of premature births.
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Authors: Ma Yanan , Cheng Yongfa , Wang Jian , Fu Si , Zhou Mengjun , Yang Yue , Li Baowen , Zhang Xin , Nan Ce‐Wen 
Published: September 2022

AbstractThe highly sensitive and degradable piezoresistive pressure sensor was constructed by coating Ti3C2Tx MXene flakes with different degrees of in situ oxidation onto the paper substrates using the dipping‐drying method. In situ oxidation tunes the intrinsic resistance and expands the interlayer distance of MXene nanosheets, which regulates the sensitivity of the sensor. It is found that the partially oxidized MXene‐based pressure sensor demonstrates remarkably higher sensitivity (28.43 kPa−1) than those of pristine MXene, over‐oxidized MXene, and state‐of‐the‐art paper‐based pressure sensors. (DOI: 10.1002/inf2.12328)
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Label‐free bacteria identification for clinical applications
Authors: Dafna Eliran , Gannot Israel 
Published: September 2022

AbstractWe have developed a system for bacteria identification based on absorption spectroscopy in the mid‐infrared spectral range. The data collected are analyzed with a deep learning algorithm. It is based on a neural‐network model which takes one‐dimensional signal vectors and outputs a probability score of identification of a bacterium type by extracting micro and macro scale features, using convolutions and nonlinear operations. The results are achieved in real time and do not require any offline postprocessing. The study was done on 12 of the most common bacteria usually seen in clinical microbiology laboratories. The system sensitivity is 0.94 ± 0.04, with a specificity of 0.95 ± 0.02. The system can be extended to additional bacterium types and variants with no change to its hardware or software, but only updating the model's parameters. The system's accuracy, size, ease of operation and low cost make it suitable for use in any type of clinical setting.
The inflammatory cellular feature in the peripheral blood of chronic subdural hematoma patients
Authors: Fan Yibing , Wu Di , Zhang Xinjie , Jiang Weiwei , Nie Meng , Liu Xuanhui , Xiang Tangtang , Liu Mingqi , Chen Yupeng , Feng Dongyi , Huang Jinhao , Gao Chuang , Jiang Rongcai 
Published: September 2022

AbstractBackgroundChronic subdural hematoma (CSDH) is a common neurosurgical disease with an increasing incidence. The absorption route of CSDH is not clear. Whether inflammatory factors enter the peripheral blood and cause systemic reactions is unknown.MethodsWe screened 105 CSDH patients and 105 control individuals. Their clinical characteristics and blood routine results were collected and compared. The blood routine changes of CSDH patients before and after treatment were compared. Age‐stratified analysis was performed due to age may affect the inflammatory markers.ResultsThe white blood cell count, absolute neutrophil count, neutrophil percentage, neutrophil‐lymphocyte count ratio (NLR), and platelet to lymphocyte count ratio (PLR) of CSDH patients before treatment were within the normal range, while were significantly higher than the control individuals (p < 0.001). The absolute lymphocyte count and lymphocyte percentage of control individuals were higher than those of patients (p < 0.001). The inflammatory cells in patients of different age groups were similar. After the patient was cured, the white blood cell count, the absolute value and percentage of neutrophils decreased (p < 0.05), while the number of monocytes increased.ConclusionsCSDH caused slight systemic inflammatory responses in the peripheral blood, implying that there is a non‐hematologic route for the absorption of hematoma.
A longitudinal study of social, religious, and spiritual capital and physical and emotional functioning in a national sample of African–Americans
Authors: Clark Eddie M. , Ma Lijing , Williams Beverly R. , Ghosh Debarchana , Park Crystal L. , Schulz Emily , Woodard Nathaniel , Knott Cheryl L. 
Published: September 2022

AbstractThe present study builds on prior research by examining the moderating relationships between different types of capital on physical functioning, emotional functioning, and depressive symptoms using a 2.5‐year longitudinal design with a national sample of African–American adults. Results indicated a significant T1 social capital × T1 religious capital interaction such that among low T1 religious capital participants, those with high T1 social capital had lower T2 physical functioning than those with lower T1 social capital. There was also a marginally significant T1 social capital × T1 spiritual capital interaction suggesting that among low T1 spiritual capital participants, those with higher T1 social capital reported a decline in depressive symptoms compared to those with lower T1 social capital. Future research and implications for intervention and policy development are discussed.
Removal of amoxicillin and ampicillin using manganese dioxide/montmorillonite composite
Authors: Valovicova Vera , Plevova Eva , Vallova Silvie , Vaculikova Lenka , Smykalova Aneta , Napruszewska Bogna D , Serwicka Ewa M , Dolinska Silvia 
Published: September 2022

AbstractBACKGROUNDClay‐based materials represent great potential for the development of efficient and environmentally friendly sorbents. The study focuses on a laboratory‐obtained manganese dioxide/montmorillonite (MnO2/MMT) composite for removal of two types of antibiotics – amoxicillin (AMX) and ampicillin (AMP) – from aqueous solution.RESULTSThe composite was successfully prepared using a reduction procedure involving the reaction between potassium permanganate (KMnO4) and hydrochloric acid (HCl) to form MnO2 followed by the addition of MMT. X‐ray analysis, scanning electron microscopy, X‐ray fluorescence and Fourier transform infrared spectroscopy were performed for characterization of physicochemical and structural properties, simultaneous thermogravimetry and differential scanning calorimetry for estimation of thermal stability and high‐performance liquid chromatography for determination of antibiotic equilibrium concentrations in aqueous solution. The precipitated MnO2 component, manifested by long fibers, corresponded to the tunnel structure of cryptomelane. In the case of MnO2/MMT it is evident that MnO2 developed short fibers with the participation of the MMT matrix. The thermal data suggested that the MnO2 phase upon contact with the clay support showed better thermal stability. The final decomposition of Mn2O3 was shifted to higher temperature of 985 °C. Adsorption procedure in a batch regimen showed sufficient sorption ability for both antibiotics with over 90% efficiency. For AMP the value of qmax was about 45 mg g−1 and for AMX it was only 21 mg g−1.CONCLUSIONSThe results provided valuable information for the design of a potentially inexpensive clay‐based adsorbent and demonstrated the removal of two types of broad‐spectrum β‐lactam antibiotics from aqueous solution to a sufficient degree. © 2022 Society of Chemical Industry (SCI).
Protein adsorption and separation with monomodal and multimodal anion exchange chromatography resins. Part I. Multicomponent adsorption properties and frontal chromatography
Authors: Roberts Joey A , Carta Giorgio 
Published: September 2022

AbstractBACKGROUNDMultimodal ion exchangers, containing ligands combining charged and hydrophobic moieties, exhibit enhanced separation compared to monomodal ion exchangers under low loading conditions. Commercial applications often require high protein loads and such conditions have not been investigated extensively, especially for multimodal anion exchangers. This work compares protein adsorption and separation by frontal chromatography for a commercial monomodal (Nuvia HP‐Q) and two multimodal anion exchangers (Nuvia aPrime and Capto Adhere) using bovine serum albumin (BSA) monomer and dimer as a model.RESULTSGreater dimer–monomer selectivity is observed for Nuvia aPrime and Capto Adhere than for Nuvia HP‐Q at low protein loads. However, binary adsorption isotherms at high protein loads show higher binding capacity and greater selectivity for Nuvia HP‐Q, despite having the same ligand density. Higher salt concentrations reduce the binding strength in all cases, but this reduction is less pronounced for the multimodal resins. As a result, selectivity increases for the latter at higher salt concentrations. Confocal laser scanning microscopy shows that, during co‐adsorption, displacement of the monomer by the dimer occurs for each resin. However, displacement becomes very slow for the multimodal resins during sequential adsorption. The multimodal resins give poorer separation by frontal chromatography, accompanied by low recovery and substantial on‐column formation of protein aggregates.CONCLUSIONThe selectivity of multimodal anion exchangers for separation of the model proteins studied varies with salt concentration and protein load. At high protein loads, multimodal resins can result in on‐column aggregate formation negatively impacting the kinetics of competitive binding and separation. © 2022 The Authors. Journal of Chemical Technology and Biotechnology published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry (SCI).
Electro‐immunosensor for ultra‐sensitive determination of cardiac troponin I based on reduced graphene oxide and polytyramine
Authors: Brussasco Jéssica G. , Guedes Pedro H. G. , Moço Anna C. R. , Moraes Dayane D. , Flauzino José M. R. , Silva Heliane S. , Silva Atair C. , Silva Jonathan P. , Madurro João M. , Brito‐Madurro Ana G. 
Published: September 2022

AbstractThis work reports the construction of a novel nanostructured immunosensor for detection of the troponin I biomarker (cTnI). Anti‐troponin I antibody was anchored on the modified graphite electrode with reduced graphene oxide and polytyramine for detection of troponin I in serum samples. The performance of the electro‐immunosensor was evaluated by differential pulse voltammetry. The immunosensor presented a wide work range, from 4 ng mL−1 to 4 pg mL−1, whose detection limit (4 pg mL−1) is significantly lower than the basal level in human serum, and maintained 100% of response after 30 days of storage. Moreover, the immunosensor showed good selectivity for detection of cTnI in real sample containing interfering substances and specificity of response to cTnI in the serum of healthy and sick patients, and demonstrated the possibility of reuse for two consecutive analyses, in addition to using a simplified and inexpensive platform when compared to other devices, demonstrating them excellent potential for application in diagnosis in the early stages of acute myocardial infarction.
Coverage of Japanese encephalitis routine vaccination among children in central India
Authors: Tandale Babasaheb V. , Deshmukh Pravin S. , Narang Rahul , Qazi Mohiuddin S. , Padmaja Goteti V. , Deshmukh Pradeep R. , Raut Abhishek V. , Narlawar Uday W. , Jha Punam Kumari , Rajderkar Shekhar S. ,   Japanese Encephalitis Epidemiology Study Group
Published: September 2022

AbstractWe aimed to estimate the coverage of Japanese encephalitis (JE) vaccination in central India to help explain the continued occurrence of JE disease despite routine vaccination. We implemented a 30‐cluster survey for estimating the coverage of JE vaccination in the medium‐endemic areas implemented with JE vaccination in central India. The parents were enquired about the uptake of the JE vaccine by their children aged 2−6 years, followed by verification of the immunization cards at home along with reasons for non‐vaccination. Vaccination coverage was reported as a percentage with 95% confidence intervals (CI). We estimated high coverage of live‐attenuated SA 14‐14‐2 JE vaccination in Maharashtra (94.8%, 95% CI: 92.7−96.3) and Telangana (92.8%, 95% CI: 90.0−94.9). The vaccination card retention was 90.3% in Maharashtra and 70.4% in Telangana state. There were no gender differences in coverage in both states. A similar level of JE vaccination coverage was observed during the year 2013−2021 in both states. In Maharashtra, the maximum age‐wise coverage was 96.6% in the >60 months age category, whereas in Telangana it was in the <24 months age category (97.2%). The timeliness of JE vaccination was appropriate and similar in both states. We found a very good agreement between JE and measles‐rubella vaccinations administered simultaneously. The reasons for non‐vaccination were the shortage of vaccines and the parental migration for work. The coverage of JE vaccination was high in medium‐endemic regions in central India. Vaccination effectiveness studies may help further explain the continued incidence of JE.
Prevalence and factors related to COVID‐19 vaccine hesitancy and unwillingness in Canada: A systematic review and meta‐analysis
Authors: Cénat Jude Mary , Noorishad Pari‐Gole , Moshirian Farahi Seyed Mohammad Mahdi , Darius Wina Paul , Mesbahi El Aouame Aya , Onesi Olivia , Broussard Cathy , Furyk Sarah E. , Yaya Sanni , Caulley Lisa , Chomienne Marie‐Hélène , Etowa Josephine , Labelle Patrick R. 
Published: September 2022

AbstractThis systematic review and meta‐analysis examined the prevalence and factors associated with vaccine hesitancy and vaccine unwillingness in Canada. Eleven databases were searched in March 2022. The pooled prevalence of coronavirus disease 2019 (COVID‐19) vaccine hesitancy and unwillingness was estimated. Subgroup analyses and meta‐regressions were performed. Out of 667 studies screened, 86 full‐text articles were reviewed, and 30 were included in the systematic review. Twenty‐four articles were included in the meta‐analysis; 12 for the pooled prevalence of vaccine hesitancy (42.3% [95% CI, 33.7%–51.0%]) and 12 for vaccine unwillingness (20.1% [95% CI, 15.2%−24.9%]). Vaccine hesitancy was higher in females (18.3% [95% CI, 12.4%−24.2%]) than males (13.9% [95% CI, 9.0%−18.8%]), and in rural (16.3% [95% CI, 12.9%−19.7%]) versus urban areas (14.1% [95%CI, 9.9%−18.3%]). Vaccine unwillingness was higher in females (19.9% [95% CI, 11.0%−24.8%]) compared with males (13.6% [95% CI, 8.0%−19.2%]), non‐White individuals (21.7% [95% CI, 16.2%−27.3%]) than White individuals (14.8% [95% CI, 11.0%−18.5%]), and secondary or less (24.2% [95% CI, 18.8%−29.6%]) versus postsecondary education (15.9% [95% CI, 11.6%−20.2%]). Factors related to racial disparities, gender, education level, and age are discussed.
Temporally compounding heatwave–heavy rainfall events in Australia
Authors: Sauter Christoph , White Christopher J. , Fowler Hayley J. , Westra Seth 
Published: September 2022

AbstractNatural hazards often occur in combination with other natural hazards rather than as isolated events. While some combinations of hazards are well studied and their physical connection is increasingly understood, other combinations have received considerably less attention. High temperatures are known to be an important component for conditions that lead to heavy rainfall; however, sequences of heatwaves followed by heavy rainfall are not well understood, especially in a compound event context. Here, we analyse heatwave–heavy rainfall events across Australia using rainfall observations at hourly resolution. Our results show that heavy rainfall is more likely to occur if preceded by a heatwave, demonstrating that heatwave–heavy rainfall sequences should be seen as temporally compounding events. In particular, many regions in Australia experience both more frequent and more extreme wet days immediately following a heatwave. This behaviour is strongest in coastal regions, especially on the Australian east coast. These findings highlight the need for heatwave–heavy rainfall sequences to be studied as compounding events, as future changes in either hazard is likely to have impacts on related risks such as flash flooding.
Predicting post‐total ankle arthroplasty walking speed based on preoperative gait mechanics
Authors: Renner Kristen , Delaney Caitlyn , Hill Cherice , Sands Laura , Queen Robin 
Published: September 2022

AbstractDecreased walking speed is associated with impaired physical performance and function in older adults. Following total ankle arthroplasty (TAA), walking speed continues to be slower than age matched controls. The purpose of this study was to determine if patients 1 year post‐TAA can achieve walking speed benchmarks and investigate if gait metrics are predictive of achieved benchmarks. 191 TAA patients were recruited and assessed pre‐TAA and 1 year post‐TAA. Kinetic and kinematic data were collected during seven self‐selected speed barefoot walking trials along a 30‐m walkway. Receiver operator curves were generated for each variable to determine threshold values needed to achieve walking speeds of 0.8, 0.9, 1.1, and 1.3 m/s. Each variable's predictive ability was classified according to the area under the curve. Ninety one percent of participants achieved a walking speed > 0.8 m/s, 85.3% achieved ≥0.9 m/s, 64.9% walked at ≥1.1 m/s, and 24.1% achieved a walking speed of 1.3 m/s by 1 year post‐TAA. Walking speed pre‐TAA was the strongest predictor with ankle moment, power and GRF data showing mixed results. Clinical Significance: 75.9% of participants were unable to walk at 1.3 m/s—a speed indicative of safely crossing a street. Variables predictive of postoperative walking speed benchmarks could be useful in developing interventions for the TAA population. The strongest predictor across all walking speed benchmarks was preoperative walking speed. A walking speed > 0.71 m/s was predictive of achieving 0.8 m/s 1 year post‐TAA, while >1.09 m/s predicted 1.3 m/s 1 year post‐TAA.
Novel slide compression anatomic plates of the femoral neck for treating unstable femoral neck fracture: A biomechanical study
Authors: Li Jia , Yin Pengbin , Li Jiantao , Zhao Zhe , Zhao Jingxin , Cui Xiang , Lyu Houchen , Zhang Licheng , Tang Peifu 
Published: September 2022

AbstractTo compare the biomechanical stability of slide compression anatomic plates of the femoral neck, cannulated compression screws and dynamic hip screws with derotation screws for stabilizing unstable femoral neck fractures (Pauwels angle = 70°). Pauwels III femoral neck fractures were created on 45 Sawbones femurs and randomly assigned to three implant groups (1:1:1). The biomechanical stability of all Sawbones in each treatment group was evaluated with three tests. First, in the static loading test, the load–displacement curve, vertical stiffness (load/vertical displacement [N/mm]) and 5 mm failure load were recorded. Second, in the incremental cyclic loading test (700, 1000, and 1400 N), the cyclic−displacement curve and the displacement of the fragments were recorded. Third, in the torsion test, the torsional rigidity, maximum torque, and torsional angle corresponding to the maximum torque were recorded. The static compression test showed that slide compression anatomic place‐femoral neck (SCAP‐FN) had the largest vertical stiffness (275 ± 11 N/mm, p < 0.01) and 5 mm failure load (1232 ± 156, p < 0.01). The cyclic loading test showed that SCAP‐FN had the lowest change in displacement after 30000 cycles of loading. The torsional stiffness and the maximum torque followed the order SCAP‐FN > dynamic hip screw systems (DHS) + derotational screw (DS) > CCS, and the torsional angle corresponding to the maximum torque followed the order SCAP‐FN < DHS + DS < CCS. The SCAP‐FN construct provides stiffness and stability compared with other standard fixation techniques (3CS and DHS + DS). The fixation strategy of SCAP‐FN might be sufficient for clinical use, indicating studies in the human body are warranted.
Ultrasound assisted treatment improves the preservation performance of chitosan‐grafted‐chlorogenic acid on refrigerated sea bass (Lateolabrax japonicus) fillets
Authors: Yang Xin , Lan Weiqing , Xie Jing 
Published: September 2022

AbstractBackgroundUltrasound can increase the mass transfer between preservatives and food, and enhances the effect of preservatives on food. Chitosan‐grafted‐chlorogenic acid (CS‐g‐CA) is a new synthetic compound with good antiseptic properties. Therefore, the present study evaluated the preservation performance of ultrasound‐assisted CS‐g‐CA (GUA) coatings on refrigerated sea bass fillets in terms of changes in microorganisms, lipids, proteins, tissue structures, and moisture.ResultsThe results showed that GUA treatment effectively inhibited the growth of microorganisms in sea bass fillets. Meanwhile, the changes in total volatile basal nitrogen, thiobarbituric acid reactive substances, and pH values were all slowed down under GUA treatment, indicating that protein degradation and lipid oxidation in sea bass were inhibited. Low‐field nuclear magnetic resonance and magnetic resonance imaging results indicated that the GUA retarded the conversion of mobile water to free water. In addition, GUA treatment maintained the flavor quality of fish fillets, and also inhibited the reduction of inosine monophosphate and the production of bitter substances (inosine and hypoxanthine), suppressed muscle tissue degeneration, and maintained better sensory scores.ConclusionOverall, GUA treatment inhibited microbial growth, protein degradation, lipid oxidation, moisture migration, decomposition of umami substances, and deterioration of sensory quality in sea bass fillets. Finally, the shelf‐life of sea bass fillets with GUA treatment was extended by an additional 9 days. The results showed that ultrasonic assistance further enhanced the effect of preservatives on aquatic products. © 2022 Society of Chemical Industry.