bluuebunny/crossref_metadata_2025_split huggingface dataset:
A longitudinal explanatory case study of coordination in a very large development programme: the impact of transitioning from a first- to a second-generation large-scale agile development method
Authors: Dingsøyr Torgeir , Bjørnson Finn Olav , Schrof Julian , Sporsem Tor 
Published: November 2022

AbstractLarge-scale agile development has gained widespread interest in the software industry, but it is a topic with few empirical studies of practice. Development projects at scale introduce a range of new challenges in managing a large number of people and teams, often with high uncertainty about product requirements and technical solutions. The coordination of teams has been identified as one of the main challenges. This study presents a rich longitudinal explanatory case study of a very large software development programme with 10 development teams. We focus on inter-team coordination in two phases: one that applies a first-generation agile development method and another that uses a second-generation one. We identified 27 coordination mechanisms in the first phase, and 14 coordination mechanisms in the second. Based on an analysis of coordination strategies and mechanisms, we develop five propositions on how the transition from a first- to a second-generation method impacts coordination. These propositions have implications for theory and practice.
Effect of sol–gel treatment on physical, chemical and mechanical stability of copper-coated conductive fabrics: focus on EMI shielding effectiveness
Authors: Periyasamy Aravin Prince , Venkataraman Mohanapriya , Militky Jiri 
Published: November 2022

AbstractThe development of electronic and communication technology keeps us updated, but it also creates electromagnetic interference (EMI), which causes infrastructure, hospitals, military facilities, nuclear power plants and delicate devices to malfunction. Therefore, it is crucial to stop the EMI-related infrastructure and electronic component failure. Copper-coated textiles are one potential example of the electrically conducting materials that might be utilized to provide an EMI shielding. However, the copper-coated materials’ performance is typically reduced by chemical and mechanical deterioration, especially when it comes to EMI shielding. In this work, we have improved their durability of Cu-coated nonwoven fibrous materials (Milife fabric) by simple silanization treatment. Later, the mechanical and chemical stability was assessed in terms of their morphology and EMI shielding effectiveness (EMSE). The silane coating helps to protect the Cu layer from degradation due to mechanical forces and chemical environment. Silanes also be a key element in obtaining improve the EMI shielding properties for a longer period. The formation of conductive structures on the fibrous materials was observed using a scanning electron microscope (SEM), which further confirms the effect of silane coating on chemical stability, abrasion and washing resistance of Cu-coated fibrous materials (cMi) was analyzed. In addition to this, the EMSE values of the silane-coated cMi fibrous materials were used to evaluate the physical, chemical and mechanical stability of the materials.
The Role of Parenthood for Life Satisfaction of Older Women and Men in Europe
Authors: Bauer Gerrit , Brandt Martina , Kneip Thorsten 
Published: November 2022

AbstractPrevious research has widely addressed the gap in well-being between parents and childless individuals. While cross-sectional studies have regularly reported lower levels of well-being for parents, recent longitudinal studies suggest a short-term positive effect with a back-to-baseline adaptation. Whether, why, and how parenthood may affect well-being in older age is, however, still largely unclear. In this paper, a holistic view of well-being developments across the process of aging is combined with a transition-centered, gender sensitive approach to analyze the effects of health decline on the self-reported life satisfaction of parents and childless individuals. Life satisfaction in older age is hypothesized to be influenced by the onset of and coping with health limitations, which themselves may differ by parental status and gender. Using group-specific growth curve analysis based on data from the Survey of Health, Ageing and Retirement in Europe (SHARE) and accounting for selection into parenthood, we demonstrate how the life satisfaction of men and women evolves in the later life depending on parental status. Results show that from age 50 onwards, parents’ life satisfaction develops somewhat less favorably compared to that of childless individuals, but this difference is not significant. However, fathers' health evolves more favorably while they react less negatively to health limitations than childless men. Our results thus suggest that children are a source of social control with long-term positive effects on health and a coping resource in the face of health limitations for fathers but not for mothers.
Czech Adolescents’ Face-to-Face Meetings With People from the Internet: The Role of Adolescents’ Motives and Expectations
Authors: Mýlek Vojtěch , Dedkova Lenka , Mesch Gustavo S. 
Published: November 2022

AbstractResearch of face-to-face meetings between adolescents and people met online stands on untested assumptions that these meetings are uniform, and adolescents attend them to expand their social circle. It is also unclear what makes such meetings pleasant or unpleasant. This study examined meetings of 611 Czech adolescents (age 11–16, Mage = 14.04, SD = 1.67, 47.1% female). Face-to-face meetings attended with friendly, romantic, or instrumental motives differed from each other, emphasizing the need to investigate them separately. Pleasantness of meetings is closely related to disconfirmation of adolescents’ expectations. Unmet expectations related to unpleasant meetings, exceeded expectations to pleasant ones. While present findings uphold existing theories (e.g., social compensation), they also call for new theoretical perspectives for this common adolescents’ activity.
The protective effects of melatonin in high glucose environment by alleviating autophagy and apoptosis on primary cortical neurons
Authors: Xiong Lijiao , Liu Song , Liu Chaoming , Guo Tianting , Huang Zhihua , Li Liangdong 
Published: November 2022

AbstractCognitive dysfunction has been regarded as a complication of diabetes. Melatonin (MLT) shows a neuroprotective effect on various neurological diseases. However, its protective effect on cortical neurons in high glucose environment has not been reported. Our present study aims to observe the protective effect of melatonin on rat cortical neurons and its relationship with autophagy in high glucose environment. The rat primary cortical neurons injury model was induced by high glucose. The CCK-8, flow cytometry, Western blot and immunofluorescence methods were used to examine the cell viability, apoptosis rate and proteins expression. Our results showed that there were no differences in cell viability, apoptosis rate, and protein expression among the control, MLT and mannitol group. The cell viability of the glucose group was significantly lower than that of the control group, and the apoptosis rate of the glucose group was significantly higher than that of the control group. Compared with the glucose group, the glucose + melatonin group showed a significant increase in cell viability and a notable decrease in apoptosis rate. Melatonin concentration of 0.1–1 mmol/L can significantly alleviate the injury of cortical neurons caused by high glucose. Compared with the control group, the glucose group showed a significant reduction of B-cell lymphoma 2 (Bcl-2) protein expression, while remarkable elevations of Bcl2-associated X protein (Bax), cleaved Caspase-3, coiled-coil, myosin-like Bcl2-interacting protein (Beclin-1) and microtubule-associated protein 1 light chain-3B type II (LC3B-II) levels. The neurons pre-administered with melatonin obtained significantly reversed these changes induced by high glucose. The phosphorylation levels of protein kinase B (Akt), mechanistic target of rapamycin kinase (mTOR) and Unc-51 like autophagy activating kinase 1(ULK1) were decreased in the glucose group compared with the control group, whereas significant increase were observed in the glucose + MLT group, compared with the glucose group. These data indicated that melatonin has a neuroprotective effect on cortical neurons under high glucose environment, which may work by activating Akt/mTOR/ULK1 pathway and may be deeply associated with the downregulation of autophagy.
In-Silico Modelling of Transdermal Delivery of Macromolecule Drugs Assisted by a Skin Stretching Hypobaric Device
Authors: Sebastia-Saez Daniel , Benaouda Faiza , Lim Chui Hua , Lian Guoping , Jones Stuart A. , Cui Liang , Chen Tao 
Published: November 2022

Abstract
Objectives
To develop a simulation model to explore the interplay between mechanical stretch and diffusion of large molecules into the skin under locally applied hypobaric pressure, a novel penetration enhancement method.

Methods
Finite element method was used to model the skin mechanical deformation and molecular diffusion processes, with validation against in-vitro transdermal permeation experiments. Simulations and experimental data were used together to investigate the transdermal permeation of large molecules under local hypobaric pressure.

Results
Mechanical simulations resulted in skin stretching and thinning (20%–26% hair follicle diameter increase, and 21%–27% skin thickness reduction). Concentration of dextrans in the stratum corneum was below detection limit with and without hypobaric pressure. Concentrations in viable epidermis and dermis were not affected by hypobaric pressure (approximately 2 μg $$\bullet$$
∙
cm−2). Permeation into the receptor fluid was substantially enhanced from below the detection limit at atmospheric pressure to up to 6 μg $$\bullet$$
∙
cm−2 under hypobaric pressure. The in-silico simulations compared satisfactorily with the experimental results at atmospheric conditions. Under hypobaric pressure, satisfactory comparison was attained when the diffusion coefficients of dextrans in the skin layers were increased from $$\sim$$
∼
10 μm2$$\bullet$$
∙
s−1 to between 200–500 μm2$$\bullet$$
∙
s−1.

Conclusions
Application of hypobaric pressure induces skin mechanical stretching and enlarges the hair follicle. This enlargement alone cannot satisfactorily explain the increased transdermal permeation into the receptor fluid under hypobaric pressure. The results from the in-silico simulations suggest that the application of hypobaric pressure increases diffusion in the skin, which leads to improved overall transdermal permeation.
The use of different LEDs wavelength and light intensities for in vitro proliferation of cherry rootstock: influence on photosynthesis and photomorphogenesis
Authors: Sarropoulou Virginia , Sperdouli Ilektra , Adamakis Ioannis-Dimosthenis , Grigoriadou Katerina 
Published: November 2022

AbstractPlant growth and development are strongly influenced by light quality conditions in their environment. In this study, in vitro shoot proliferation, photosynthetic pigments, leaf anatomy and photosystem II photochemistry of Gisela 6 cherry rootstock (Prunus cerasus x Prunus canescens) were investigated. The culture medium used was the MS (Murashige and Skoog) containing 4.4 μΜ 6-benzyladenine (BA), 0.05 μΜ α-naphthalene acetic acid (NAA) and 0.3 μM gibberellic acid (GA3) (30 days, 16 h photoperiod, 22 ± 2 °C). Initially, two different light wavelength absorption spectra: 400–700 nm provided by white fluorescent light lamps (mainly blue–green, BG at equal ratio 1:1; WFL-40) and, 430–690 nm provided by two Light Emitting Diodes (LED) types, differing in the spectral ratio of multiple light emitting wavelengths [LED2-40 (blue–red, BR) and LED3-40 (blue–green–yellow–orange–red, BGYOR)] were studied, under 40 μmol m−2 s−1 of light intensity. Following that, three LED intensities-20 (LED1-20), 40 (LED2-40), and 120 μmol m−2 s−1 (LED4-120) were investigated under BR spectrum. WFL-40 exhibited non-significant differences with LED2-40 (shoot number 4.25, proliferation rate 4.30, shoot height 0.91 cm). LED2-40 displayed higher fresh and dry shoot biomass, better PSII functionality, increased Chl a/b, Chl b and carotenoids content as well as decreased number of stressed explants. Leaf anatomy under LED2-40 and WFL-40 was similar. LED4-120 presented the highest rate of stressed explants, with their leaf anatomy being severely affected, as leaves had a reduced mesophyll cell density. In LED4-120, the proportion of the absorbed energy used in photochemistry (ΦPSII) was decreased whereas the increased quantum yield of non-regulated energy loss in PSII (ΦNO) could not be compensated by the increased photoprotective energy dissipation (ΦNPQ). Therefore, LED2-40 is proposed as the most beneficial for growing cherry rootstock Gisela 6 plantlets in vitro.
Cross-sectional E-survey on the Incidence of Pre- and Postoperative Chronic Pain in Bariatric Surgery
Authors: Torensma Bart , Hany Mohammed , Bakker Marije J. S. , van Velzen Monique , in ’t Veld Bas A. , Dahan Albert , Swank Dingeman J. 
Published: November 2022

Abstract
Background
To assess the prevalence, incidence, location, and behavior of chronic pre- and postoperative pain in bariatric surgery, and the use of analgesics.

Methods
A cross-sectional e-survey was conducted on 3928 post-bariatric patients and four-time points for pain assessment were evaluated: preoperative, on the ward, day 1 at home postoperatively, and present time (at the time of the e-survey). A numerical rating scale (NRS) was used to assess the level of pain (0 to 10). The general incidence of chronic pain was calculated, as also, subgroups were defined as group A (pre and postoperative chronic pain), B (preoperative pain, and no longer postoperative), and C (preoperative painless, postoperative chronic pain). Besides the pain intensity, location of pain, and the use of analgesics were investigated.

Results
A total of 3279 patients (83.9%) responded to the survey. Preoperative and postoperative chronic pain was found in 343 (10.5%) and 264 (8.1%) patients, respectively. In group A, chronic pain was present in 4.8% of the patients; in group B, it was present in 5.7%; and in group C in 3.3% of the patients. Furthermore, in 4.5% of patients pain was located in the abdomen, which was higher as compared to before surgery (+ 2.3%, p < 0.001). The ORs for present postoperative chronic pain were OR 1.45, 1.7, and 1.71 (p = 0.002, 0.003, 0.003) compared to respectively preoperative chronic pain, pain at the ward, and pain at day 1 after surgery. Among all participants, 4.6% consumed chronic analgesics. Of these, paracetamol was used most frequently (3.8%), followed by tramadol (1.3%) and oxycodone (0.5%).

Conclusions
In this e-survey, chronic postoperative abdominal pain was prominent in patients after bariatric surgery. Of patients, 3.3% that were without preoperative chronic pain developed chronic pain after surgery. Opioid consumption in the queried population was relatively low.

Graphical Abstract
Taking advantage of Li-evaporation in LiCoO2 as cathode for proton-conducting solid oxide fuel cells
Authors: Xu Yangsen , Yu Shoufu , Yin Yanru , Bi Lei 
Published: November 2022

AbstractLiCoO2, a widely used electrode material for Li-ion batteries, was found to be suitable as a cathode material for proton-conducting solid oxide fuel cells (H-SOFCs). Although the evaporation of Li in LiCoO2 was detrimental to the Li-ion battery performance, the Li-evaporation was found to be beneficial for the H-SOFCs. The partial evaporation of Li in the LiCoO2 material preparation procedure led to the in-situ formation of the LiCoO2+Co3O4 composite. Compared to the cell using the pure phase LiCoO2 cathode that only generated moderate fuel cell performance, the H-SOFCs using the LiCoO2+Co3O4 cathode showed a high fuel cell performance of 1160 mW·cm−2 at 700 °C, suggesting that the formation of Co3O4 was critical for enhancing the performance of the LiCoO2 cathode. The first-principles calculation gave insights into the performance improvements, indicating that the in-situ formation of Co3O4 due to the Li-evaporation in LiCoO2 could dramatically decrease the formation energy of oxygen vacancies that is essential for the high cathode performance. The evaporation of Li in LiCoO2, which is regarded as a drawback for the Li-ion batteries, is demonstrated to be advantageous for the H-SOFCs, offering new selections of cathode candidates for the H-SOFCs.
Obesità: genetica e dintorni
Authors: Masi Davide , Tozzi Rossella , Watanabe Mikiko 
Published: November 2022

SommarioL’obesità è una malattia metabolica cronica associata a diverse complicanze. Alla base non vi è solo l’alimentazione, poiché il bilancio energetico è regolato da interazioni tra fattori genetici, comportamentali e ambientali. Gli studi di associazione sul genoma identificano diversi geni legati all’obesità, suggerendo nuovi orizzonti terapeutici nel genome editing: la tecnologia CRISPR/Cas9, modificando il DNA o modulando l’espressione genica nelle cellule eucariotiche, fa luce sui meccanismi genetici e potrebbe essere un valido strumento terapeutico. Questa rassegna riassume la genetica dell’obesità e i trattamenti disponibili, discutendo i progressi della ricerca sul genome editing nella conoscenza e terapia dell’eccesso di grasso corporeo.
Different pathways of the second demographic transition in four East Asian societies: evidence from the 2006 and 2016 East Asian Social Surveys
Authors: Lai Weiwen , Song Jing 
Published: November 2022

AbstractThis study uses the 2006 and 2016 East Asian Social Surveys to map value changes related to the second demographic transition in mainland China, Japan, South Korea, and Taiwan. The study examines trends in attitudes towards cohabitation, childrearing, and divorce over a 10-year period in the four East Asian societies. The findings suggest that the second demographic transition, if any in East Asia, is an uneven process between societies, and mainland China stands out as the only society in which attitudes had become more conservative, even after controlling for compositional differences in population. In the other three societies, attitudes had shifted to be more liberal. Moreover, the study finds little evidence on the diffusion within societies, given their similar trends across different sociodemographic groups. From an ideational perspective, mainland China and the other three East Asian societies illustrated different patterns of attitude changes regarding marriage and family. From a behavioral perspective, trends in attitudes do not always align with demographic patterns at the macro level, especially in mainland China. More studies are needed to understand the nuanced differences in ideational shifts between societies and the relationship between ideational and behavioral changes in East Asia.
On decay–surge population models
Authors: Goncalves Branda , Huillet Thierry , Löcherbach Eva 
Published: November 2022

AbstractWe consider continuous space–time decay–surge population models, which are semi-stochastic processes for which deterministically declining populations, bound to fade away, are reinvigorated at random times by bursts or surges of random sizes. In a particular separable framework (in a sense made precise below) we provide explicit formulae for the scale (or harmonic) function and the speed measure of the process. The behavior of the scale function at infinity allows us to formulate conditions under which such processes either explode or are transient at infinity, or Harris recurrent. A description of the structures of both the discrete-time embedded chain and extreme record chain of such continuous-time processes is supplied.
Subsidiarity and the Allocation of Governmental Powers
Authors: Da Silva Michael 
Published: November 2022

AbstractEvery country must allocate final decision-making authority over different issues/subjects within its boundaries. Historically, many scholars working on this topic implicitly assumed that identifying the features providing entities with justified claims for authority and the entities possessing those features would also identify which groups should have which powers (or vice versa). However, many candidate allocative principles select multiple entities as candidates for some sub-state authority and yet fail to explain which powers each should possess. Further work must explain which groups should possess which powers when and what to do when two groups can make equally-valid authority claims using the same principle. Subsidiarity, the principle under which authority should presumptively belong to the entity representing those ‘most affected’ by its exercise and capable of addressing underlying problems, is one of the few principles focused on identifying which groups should have which powers. Unfortunately, subsidiarity alone does not provide guidance on many issues/subjects. Useful subsidiarity-related guidance relies on balancing underlying justificatory interests, which do the real allocative work. Another allocative principle remains necessary. A deflationary account of subsidiarity’s allocative potential nonetheless provides insights into how to articulate a new principle and accounts of subsidiarity that can fulfill other moral roles.
Impacto económico de las intervenciones no farmacéuticas adoptadas por la COVID-19: El caso de Paraguay
Authors: Blanco Cesar , Rivas Gustavo 
Published: November 2022

ResumenEl objetivo de este trabajo es cuantificar la relación negativa entre actividad económica y la contención de la COVID-19 mediante la implementación de intervenciones no farmacéuticas en Paraguay. Para esto, calibramos el modelo desarrollado por Eichenbaum, Rebelo y Trabandt con datos de Paraguay. Utilizamos el modelo para simular la trayectoria de la actividad económica, dados distintos escenarios de infección. Consideramos tres casos de estudio. En el primero, consideramos una flexibilización de las medidas de intervención no farmacéuticas aún vigentes. En el segundo, estudiamos el impacto económico de contener una aceleración de la infección. En el tercer caso, analizamos una reducción de la infección y su efecto en la economía. Mediante el estudio de estos casos obtenemos una aproximación del costo económico de contener la infección.
Aporías del Foro Nacional de Agricultura Familiar
Authors: Berger Matías , Ramos Berrondo Jimena 
Published: November 2022

ResumenEl objetivo de este artículo es analizar el Foro Nacional de Agricultura Familiar como dispositivo estatal de participación y encuadramiento de los sujetos subalternos rural-agrarios en Argentina. Para ello, retomamos los estudios y debates nacionales e internacionales sobre comportamiento y participación política en áreas rurales. Luego, desde un enfoque etnográfico, analizamos las tramas organizacionales y el proceso de configuración de este dispositivo describiendo las diferentes perspectivas de los agentes involucrados: funcionarios políticos, agentes estatales y dirigentes. Como resultado, elaboramos una tipología de organizaciones a partir de analizar la estructura y el volumen del capital de sus agentes.