bluuebunny/crossref_metadata_2025_split huggingface dataset:
Загальні принципи розрахункової оцінки сейсмічної міцності чавунного обладнання енергоблоків атомних станцій відповідно до нормативних вимог
Authors: Shugaylo O-r , Ryzhov D. , Krugliy Ya. , Kohan V. 
Published: June 2022

Згідно з вимогами до сейсмостійкого проєктування та оцінки сейсмічної безпеки енергоблоків атомних станцій обґрунтування сейсмостійкості обладнання, трубопроводів атомних станцій та їхніх опорних конструкцій виконується розрахунковими, експериментальними методами або їх комбінацією з урахуванням чинних нормативних документів та стандартів. Отже, під час оцінки сейсмічної міцності чавунного обладнання енергоблоків атомних станцій фахівець має обрати нормативні документи та стандарти, відповідно до яких виконувати розрахунки. Вирішення питання коректного вибору нормативних документів, стандартів та підходів до оцінки сейсмічної міцності чавунного обладнання енергоблоків атомних станцій зумовлює певні складнощі.
У статті описано аналіз та обґрунтовано вибір нормативних документів та стандартів для розрахункової оцінки сейсмічної міцності чавунного обладнання енергоблоків атомних станцій. Наведено розроблені загальні принципи розрахункової оцінки сейсмічної міцності чавунного обладнання енергоблоків атомних станцій.
Стаття входить до циклу публікацій в журналі «Ядерна та радіаційна безпека», присвячених розгляду різних аспектів практичного застосування нормативних вимог до оцінки сейсмостійкості елементів атомних станцій.
Analisis Pengendalian Kualitas Produk Pipa PVC AW 4 Supralon dengan Metode Statistical Quality Control (SQC) dan New Seven Tools di PT XYZ
Authors: Pratiwi Irma Dian , Ngatilah Yustina 
Published: June 2022

XYZ adalah perusahaan yang bergerak di bidang usaha pembuatan Pipa PVC dan HDPE. Permasalahan yang sering terjadi di dalam perusahaan adalah terdapat produk defect yang menyebabkan proses produksi pipa PVC tidak efektif dan menyebabkan perusahaan rugi. Penelitian dilakukan denganmenggunakan metode Statistical Quality Control (SQC) dengan rekomendasi perbaikan New Seven Tools. Penelitian dengan menggunakan metode ini digunakan untuk mengetahui penyebab defect pada produk dan dapat memberikan usulan perbaikan untuk pencegahan agar defect tersebut berkurang. Dalam hal ini terdapat 4 jenis defect pada pipa PVC yang diproduksi oleh PT. XYZ yaitu defect pipih, Retak atau Pecah, Lubang dan warna. Untuk presentase defect pada pipa PVC AW Supralon adalah sebesar 5,03% dari jumlah defect sebesar 5.748 lonjor dan dengan total produksi sebesar 114.255 lonjor. Akar masalah penyebab defect yang paling dominan yang sering terjadi diantaranya operator tidak menerapkan SOP dalam bekerja, komposisi bahan baku tidak stabil,tidak ada penjadwalan maintenance secara berkala dan pencampuran bahan baku yang kurang homogen. Adapun rekomendasi perbaikannya adalah diberikan arahan dalam bekerja agar tidak lalai dan lebih teliti serta melakukan pengontrolan dan pengawasan pada saat proses produksi, dilakukan breafing dan arahan sebelum On mesin, dilakukan pengoptimalan kinerja operator, serta Pengkondisian, pengecekan dan pengukuran bahan baku yang sesuai dengan ketentuan perusahaan, dilakukan jadwal pengecekan dalam proses produksi setiap hari dan tune up mesin satu minggu sekali.
ANALISIS PENGENDALIAN KUALITAS PRODUK KONVEKSI DENGAN MENGGUNAKAN METODE SIX SIGMA PADA PT. XYZ
Authors: Qothrunnada Alisa , Dimas Herlambang Putra  , Jasur  , Isna Nugraha  
Published: June 2022

ABSTRAK
Kualitas konveksi sebagai bahan baku dalam proses produksi memiliki peran penting. Pengendalian kualitas konveksi merupakan kunci dalam mempertahankan hasil produksi. Hal inilah yang mendasari tujuan penelitian ini untuk melakukan upaya perbaikan dalam aktivitas produksinya dengan menekan angka produk cacat dalam proses produksinya. Pengendalian kualitas konveksi dilakukan dengan menentukan beberapa parameter yaitu pemotongan, bordir, penjahitan dan finishing. Penelitian ini menggunakan metode Six Sigma dengan konsep DMAIC. Dengan menggunakan diagram Pareto diketahui bahwa kecacatan berada pada proses pemotongan, bordir, penjahitan dan finishing. Selanjutnya, diagram fishbone digunakan guna mengetahui persentase cacat terbesar. Perbaikan dilakukan dengan FMEA pada nilai RPN tertinggi yaitu pada proses pemotongan. Sebagai tambahan, nilai level sigma adalah 3.38503 dengan kemungkinan cacat sebesar 9379 untuk sejuta proses.

Kata Kunci: DMAIC, Pengendalian Kualitas, Produk Konveksi, Six Sigma.

ABSTRACT
The quality of convection as a raw material in the production process has an important role. Convection quality control is the key in maintaining production results. This is what underlies the purpose of this research to make efforts to improve its production activities by reducing the number of defective products in the production process. Convection quality control is carried out by determining several parameters, namely cutting, embroidery, sewing and finishing. This study uses the Six Sigma method with the DMAIC concept. By using the Pareto diagram, it is known that the defects are in the cutting, embroidery, sewing and finishing processes. Furthermore, the fishbone diagram is used to determine the largest percentage of defects. Improvements are made with FMEA at the highest RPN value, namely in the cutting process. In addition, the sigma level value is 3.38503 with a possible defect of 9379 for a million processes.

Keywords: DMAIC, Quality Control, Connvection Product, Six Sigma,
PERENCANAAN KEBUTUHAN KAPASITAS WAKTU PRODUKSI PIPA SPIRAL DENGAN METODE CAPACITY REQUIREMENT PLANNING
Authors: Rusindianto  , Winursito Yekti Condro 
Published: June 2022

Setiap perusahaan memerlukan sumber daya dalam menjalankan proses produksinya. Perusahaan dituntut untuk dapat menyiapkan produk dalam jumlah berapapun pada waktu yang cepat sesuai dengan keinginan konsumen. PT X merupakan perusahaan manufaktur yang bergerak dalam bidang industri pengecoran logam dan salah satu produk yang dihasilkan adalah pipa spiral. PT X sering mengalami beberapa permasalahan yang dihadapi, salah satunya yaitu kurang optimalnya perencanaan kebutuhan kapasitas waktu produksi pada produksi pipa spiral sehingga mengganggu kelancaran jadwal produksi dan menimbulkan kerugian dari segi waktu maupun biaya. Berdasarkan permasalahan tersebut maka perlu dilakukan perencanaan kebutuhan kapasitas produksi pipa spiral dengan menggunakan metode Capacity Requirement Planning untuk menyesuaikan tingkat kedatangan permintaan sesuai dengan kapasitas waktu yang tersedia. Dari hasil pengolahan data dengan menggunakan metode perusahaan dan metode CRP maka dapat diketahui bahwa dengan metode perusahaan mengalami total kekurangan kapasitas waktu sebesar 549,77 jam, sedangkan menggunakan metode CRP mengalami kekurangan kapasitas waktu sebesar 288,2 jam sehingga dapat dinilai bahwa metode CRP lebih baik karena kekurangan kapasitas waktu yang dihasilkan lebih kecil dibandingkan dengan metode yang selama ini digunakan oleh perusahaan.
RANCANGAN ALAT PENDORONG KURSI RODA OTOMATIS DENGAN BIAYA YANG EFEKTIF MENGGUNAKAN METODE VDI 2221
Authors: Sumiati  , Isna Nugraha  , Rino Bagus Putra Pratama  
Published: June 2022

ABSTRAK
Kursi roda adalah alat bantu yang digunakan oleh orang yang mengalami kesulitan berjalan menggunakan kaki, baik dikarnakan penyakit cedera, maupun cacat. Penelitian ini dibuat untuk mengatasi permasalahan pada saat perpindahan mengunakan kursi roda ketempat yang jauh tanpa mengeluarkan biaya yang besar untuk membeli kursiroda elektrik, yaitu dengan membuat alat bantu untuk diaplikasikan pada kursi roda kovensional. Maka dibuatlah penelitian dengan menggunakan metode VDI 2221 untuk menentukan desain pengembangan alat yang optimal agar mencapai biaya yang minimal serta waktu perakitan yang minim (mudah dibuat). Dari hasil pengolahan data nilai total yang paling tinggi diantara alternatif rancangan atau varian lainnya, yaitu sebesar 8,03. Dengan konstruksi yang tidak terlalu rumit sehingga mudah dibuat. Dalam perakitan alat pendorong otomatis membutuhkan waktu pengerjaan alat pendorong otomatis secara keseluruhan mulai dari tahap awal sampai dengan tahap akhir, waktu yang dibutuhkan adalah 222,05 menit. Serta memiliki efisiensi perakitan sebesar 0,4053. Perakitan alat pendorong ini membutuhkan 10 macam komponen dan material dengan biaya pembuatan sebesar Rp. 2.204.000,00.

Kata Kunci: Desain Produk, Efisiensi Perakiran , VDI 2221.

ABSTRACT
Wheelchairs are assistive devices used by people who have difficulty walking on foot, both due to injury and disability. This study was made to overcome problems at the time of transfer using a wheelchair in a distant place without spending a lot of money to buy an electric chair, namely by making a tool to apply to a conventional chair.
Then a research was made using the VDI 2221 method to determine the design of optimal development tools to achieve minimal costs and minimal assembly time (easy to make). From the results of processing the highest total value data among alternative designs or other variants, that is equal to 8.03. With construction that is not too complicated so it is easy to make. In the assembly of automatic propulsion equipment requires automatic working time of the pusher starting from the initial stage to the final stage, the time taken is 222.05 minutes. And has an assembly efficiency of 0.4053. The assembly of the pusher requires 10 components and materials with a manufacturing cost of IDR. 2.204.000,00.
Older forensic mental healthcare patients in England: demographics, physical health, mental wellbeing, cognitive ability and quality of life
Authors: Tomlin Jack , Walker Kate , Yates Jen , Dening Tom , Völlm Birgit , Griffiths Chris 
Published: June 2022

Background: Older individuals (e.g., 55 years and over) constitute a growing proportion of the forensic mental health patient population. As a group, they are vulnerable to health outcomes similar to other individuals with serious mental disorders of the same age; however, these concerns can be compounded by complex forensic-related care backgrounds and clinical presentations, lengthy periods of time spent in prison or psychiatric hospitals, substance use histories, and crime perpetration or victimisation. The healthcare needs and strengths of this group are not well understood. The aim of this study was to identify and describe the demographic, physical health, mental wellbeing, cognitive ability, and quality of life profiles of older forensic patients in community, low, medium, and high security settings in England. Methods: A cross-sectional quantitative study design was used. N=37 forensic patients aged 55 years and over completed six questionnaires. Data were also collected from patient records. Results: Most patients were male and were diagnosed with psychosis. The most frequently committed index offence types were violent offences. Patients were prescribed 7.6 medications on average and had average anticholinergic effect on cognition scores of 2.4. Nearly half the sample had diabetes, with an average BMI score of 31.7 (indicating obesity). Possible cognitive impairment was identified in 65% of the sample. Patients’ assessments of their recovery-related quality of life and mental wellbeing were comparable to published UK general population values. Assessments of quality of life were positively correlated with the ability to undertake everyday activities and cognitive performance. Conclusions: We suggest that forensic services are well-placed to provide holistic mental and physical care to this group but that they should co-develop with patients a greater range of age-appropriate meaningful activities that are mindful of mobility issues and consider implementing more cognition-based and physical health interventions.
Участь бензодіазепінових рецепторів у механізмі анксіолітичної дії синтетичного аналога кінцевого фрагмента нейропептиду Y
Authors: Гаврилов І. О. , Штриголь С. Ю. 
Published: June 2022

Мета дослідження – виявити можливу участь бензодіазепінових рецепторів в анксіолітичному ефекті нового модифікованого аналога нейропептиду Y – нонапептиду NP9.
Експеримент проведено на 43 білих нелінійних мишах масою 25–30 г з використанням тесту «Піднесений хрестоподібний лабіринт». Нонапептид NP9 вводили інтраназально в дозі 0,2 мг/кг. Як препарат порівняння використовували Семакс (Пептоген, Росія) у дозі 0,1 мг/кг інтраназально. Для вивчення можливої участі ГАМКА-рецепторного комплексу в механізмі дії NP9 використовували селективний антагоніст бензодіазепінових рецепторів – флумазеніл 15 мг/кг внутрішньоочеревинно. Нонапептид NP9 зменшував тривожність тварин у тесті «Піднесений хрестоподібний лабіринт», але на тлі флумазенілу маркери анксіолітичної активності знижувались до рівня контролю та значно поступалися показникам впливу NP9 per se. Семакс не виявив протитривожних властивостей, а флумазеніл не вплинув на його поведінкові ефекти. Таким чином, у механізмі анксіолітичної дії нонапептиду NP9 беруть участь бензодіазепінові рецептори.
The Effect Of 5% Da On Blood Glucose Level Using As Irrigant During The Procedure Of Turp
Authors: Haque Mohammed Monowar Ul , Islam Md Hafizul , Siddique Syeda Rumman Aktar 
Published: June 2022

During TURP 1.5% Glycine is a conventional fluid being used as irrigant worldwide. Now a days we are also using 5% Dextrose in Aqua as an irrigant. The aim of this study is to observe the changes in blood glucose level by using 5% dextrose in aqua as an irrigation fluid in TURP for BPH. This was a observational study, conducted on 50 non diabetic BPH patients admitted in the department of Urology, CMCH between 01January, 2006 to 31December, 2007. TURP was done on these patients using.5% Dexrose in Aqua as irrigant. Blood glucose level was recorded pre operatively (24 hr. before opn.), immediate post operatively (5 minutes after surgery) and 24 hour after surgery. Post operative results compared with preoperative values. 2 cases were excluded from current study and rest 48 patients were included into the study. Mean pre operative blood glucose level was 5.97 (+0.60) mmol/L, then it was increased to 6.64 (+0.50) mmol/L,which was significant (P<0.01) in immediate post operative period. The value then reduced to 6.28 (+0.49) mmol/L (P<0.05) 24 hour after surgery. which were within the normal serum glucose level. All the values returned towards pre operative level and the changes were not significant. So, we can do the TURP in remote part of Bangladesh by using 5% DA as an irrigant without fear of blood glucose change.
JCMCTA 2013 ; 24 (2): 19-21
Congenital Adrenal Hyperplasia: A Case Report
Authors: Das Jagadish C , Khanam Mursheda , Islam Rezina 
Published: June 2022

Congenital adrenal hyperplasia (CAH) is rare condition with different presentations. The most important 'salt loosing' variant is a medical emergency. More than 90% of cases of congenital adrenal hyperplasia are caused by 21 a-hydroxylase deficiency (21aOH). Rather than cortisol, the adrenals produce excess sex hormone. Majority of patients cannot synthesize sufficient aldosterone. There is virilization of girls, rapid somatic growth with early epiphyseal fusion in both sexes and even life threatening hyponatremic dehydration. The present case presented on 5th postnatal day with unrecognized sex and repeated vomiting. The baby was hyperpigmented, dehydrated with ambiguous genitalia. Hyponatremic, hyperkalemic hypochloremic metabolic acidosis with normal renal profile was seen. Both adrenal glands were enlarged with presence of uterus. Serum cortisol level was low but testosterone level was very high. The newborn was treated as congenital adrenal hyperplasia with hydrocortisone, fludrocortisones, calcium gluconate and 10% dextrose in 0.45% NaCl solution. Significant clinical improvement was observed within a week in this case. The case was presented with a view to focus such rare medical emergency so that Pediatricians and Neonatologists could manage the problem timely.
JCMCTA 2013 ; 24 (2): 44-47
An Analysis of Lexemic Idiomatic Expressions in Eaternal Nocturnal Webtoon
Authors: Carishma Sasqia Salsabilla , Zahrida Zahrida , Elfrida Elfrida 
Published: June 2022

This research aims to determine the types and meanings of lexemic idiomatic expressions in the Eaternal Nocturnal webtoon. This research used a qualitative method. The object of this research is the script of dialogues and narrations of the characters in Eaternal Nocturnal webtoon, namely episode two to episode six. The researcher used data sheets and tables as instruments. The researcher identified and categorized each expression based on Makkai's theory (1972) and using three dictionaries related to idioms, namely Farlex Dictionary of Idioms, Dictionary of American Idioms by McGraw-Hill's, and NCT's American Idioms Dictionary, then matched the meanings of lexemic idiomatic expressions from the dictionaries with the co-text contained in the dialogues or narrations of the characters to analyze the data. The results showed that there were six types of lexemic idiomatic expressions in the Eaternal Nocturnal webtoon, namely Phrasal Verb idioms, Tournure idioms, Irreversible Binomial idioms, Phrasal Compound idioms, Incorporating Verb idioms, and Pseudo idioms. In determining the meaning must be based on the co-text because an idiom contains many meanings. Keywords: Idiomatic, Lexemic Idiomatic Expressions, Webtoon
Tratamiento del Edema, uso racional y fisiológico de diuréticos
Authors: Tapia Hugo R. 
Published: June 2022

Los diuréticos son agentes farmacológicos utilizados para tratar pacientes que desarrollan retención de sodio y edema. Los diuréticos actúan en sitios específicos en el nefrón, y cuyo efecto es disminuir la reabsorción de sodio y facilitar su excreción renal. Su uso racional y fisiológico requiere un conocimiento básico de su farmacocinética y farmacodinámica, así como de sus posibles efectos secundarios y complicaciones. Aunque los diuréticos se usan en condiciones no edematosas, el enfoque principal de este artículo es el uso de diuréticos en situaciones clínicas caracterizadas por la expansión del compartimiento extracelular con desarrollo de edema.
Metascan: METabolic Analysis, SCreening and ANnotation of Metagenomes
Authors: Cremers Geert , Jetten Mike S. M. , Op den Camp Huub J. M. , Lücker Sebastian 
Published: June 2022

Large scale next generation metagenomic sequencing of complex environmental samples paves the way for detailed analysis of nutrient cycles in ecosystems. For such an analysis, large scale unequivocal annotation is a prerequisite, which however is increasingly hampered by growing databases and analysis time. Hereto, we created a hidden Markov model (HMM) database by clustering proteins according to their KEGG indexing. HMM profiles for key genes of specific metabolic pathways and nutrient cycles were organized in subsets to be able to analyze each important elemental cycle separately. An important motivation behind the clustered database was to enable a high degree of resolution for annotation, while decreasing database size and analysis time. Here, we present Metascan, a new tool that can fully annotate and analyze deeply sequenced samples with an average analysis time of 11 min per genome for a publicly available dataset containing 2,537 genomes, and 1.1 min per genome for nutrient cycle analysis of the same sample. Metascan easily detected general proteins like cytochromes and ferredoxins, and additional pmoCAB operons were identified that were overlooked in previous analyses. For a mock community, the BEACON (F1) score was 0.72–0.93 compared to the information in NCBI GenBank. In combination with the accompanying database, Metascan provides a fast and useful annotation and analysis tool, as demonstrated by our proof-of-principle analysis of a complex mock community metagenome.
Meta-Analysis of Relationship of Sleep Quality and Duration With Risk of Diabetic Retinopathy
Authors: Zheng Zhenzhen , Wang Chaoyu , Li Chunhe , Wu Qinglan , Chen Xiaojuan , Chen Huimin , Liao Huizhao , Zhu Jinru , Lin Junyan , Ou Xudong , Zou Zhihong , Liang Jinhua , Chen Riken 
Published: June 2022

ObjectiveA meta-analysis is used to explore the relationship of sleep quality and duration with the risk of diabetic retinopathy (DR).MethodCochrane Library, PubMed, Embase, and other databases are searched from their establishment to April 2022. Literature on the relationship of sleep quality and duration with DR risk published in various databases is collected, and two researchers independently screen the literature, extract data, and evaluate the quality of the included articles. The meta-analysis is performed with Review Manage 5.4.1 software.ResultsA total of 7 articles are selected, including 4,626 subjects. The results show a strong correlation between sleep quality and DR risk. When comparing the sleep quality scores of “DR” (experimental group) and “NO DR” (control group), the Pittsburgh sleep quality index(PSQI) score of the DR group is significantly higher than that of the NO DR group (MD = 2.85; 95% confidence interval [CI] 1.92, 3.78, P&lt;0.001), while the ESS score of the DR group is also significantly higher than that of the NO DR group (MD = 1.17; 95% confidence interval [CI] 0.14 to 2.30, P=0.04), so the sleep quality score of the DR group is higher than that of the NO DR group in both the PSQI and ESS scores, which confirms that low sleep quality is a risk factor for DR. Long sleep duration is also associated with the risk of developing DR; the number of adverse events (DR prevalence) is higher for “long sleep duration” than “normal sleep duration” [OR = 1.83, 95%CI 1.36–2.47, P &lt; 0.001], suggesting that long sleep duration can cause increased DR risk. Short sleep duration is also associated with the occurrence of DR [OR = 1.49, 95%CI 1.15–1.94), P = 0.003] and can increase DR risk.ConclusionSleep quality and duration (including long and short sleep duration) are significantly associated with DR. To reduce DR risk, sleep intervention should be actively carried out, lifestyle changes should be made, and attention should be paid to the role of DR management.
Diagnostic Accuracy of Artificial Intelligence (AI) to Detect Early Neoplasia in Barrett's Esophagus: A Non-comparative Systematic Review and Meta-Analysis
Authors: Tan Jin Lin , Chinnaratha Mohamed Asif , Woodman Richard , Martin Rory , Chen Hsiang-Ting , Carneiro Gustavo , Singh Rajvinder 
Published: June 2022

Background and AimsArtificial Intelligence (AI) is rapidly evolving in gastrointestinal (GI) endoscopy. We undertook a systematic review and meta-analysis to assess the performance of AI at detecting early Barrett's neoplasia.MethodsWe searched Medline, EMBASE and Cochrane Central Register of controlled trials database from inception to the 28th Jan 2022 to identify studies on the detection of early Barrett's neoplasia using AI. Study quality was assessed using Quality Assessment of Diagnostic Accuracy Studies – 2 (QUADAS-2). A random-effects model was used to calculate pooled sensitivity, specificity, and diagnostics odds ratio (DOR). Forest plots and a summary of the receiving operating characteristics (SROC) curves displayed the outcomes. Heterogeneity was determined by I2, Tau2 statistics and p-value. The funnel plots and Deek's test were used to assess publication bias.ResultsTwelve studies comprising of 1,361 patients (utilizing 532,328 images on which the various AI models were trained) were used. The SROC was 0.94 (95% CI: 0.92–0.96). Pooled sensitivity, specificity and diagnostic odds ratio were 90.3% (95% CI: 87.1–92.7%), 84.4% (95% CI: 80.2–87.9%) and 48.1 (95% CI: 28.4–81.5), respectively. Subgroup analysis of AI models trained only on white light endoscopy was similar with pooled sensitivity and specificity of 91.2% (95% CI: 85.7–94.7%) and 85.1% (95% CI: 81.6%−88.1%), respectively.ConclusionsAI is highly accurate at detecting early Barrett's neoplasia and validated for patients with at least high-grade dysplasia and above. Further well-designed prospective randomized controlled studies of all histopathological subtypes of early Barrett's neoplasia are needed to confirm these findings further.