bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation of child nutrition anthropometry pocketbook for early childhood education to increase the ability of teachers to assess nutritional status of early childhood education students in Gianyar Regency, Bali, Indonesia
Authors: Ariati Ni Nengah , Wiardani Ni Komang , Kusumajaya Anak Agung Ngurah , Fetria Arma 
Published: February 2022

Introduction: The age of preschool children is the golden age where the physical and psychological is rapidly developing then it is necessary to fulfil the nutritional needs. This is a period that is vulnerable to under-nutrition and over-nutrition. To deal with these problems, nutritional monitoring status must be carried out jointly between teachers, parents, and health care workers. Most early childhood education teachers have not assessed children's nutritional status and only weighed them. Based on these problems, the early childhood education Anthropometry Pocket Book was made to assist teachers in determining the nutritional status of children.Method: The study used a different subject design and was carried out in April-October 2021 involving 52 samples, divided into two groups, namely the Control Group with 26 people and the Treatment Group with 26 people. The data collected such as sample identity and data on the ability of teachers to assess nutritional status using the BW/Age, Height/Age, BW/H, and BMI/A indexes before and after the intervention in the Control and Treatment Group. The data were analyzed descriptively by looking for the mean, standard deviation, and different tests were carried out to determine the difference in the effect of treatment on the control group and the treatment group, statistical tests Independent samples t-test at significance level (0.05) used on homogeneous data and Mann Whitney test on inhomogeneous data.Result: The results showed that the average ability of teachers to assess children’s nutritional status in the Treatment Group was higher than the Control Group after being given the intervention. The enhancement before and after intervention in the control group with body weight/age (BW/A) index was 69.1%, height/ age (H/A) was 67.0%, BW/A was 71.5%, and body mass index/age (BMI/A) was 95.4%. While the increase in the Treatment Group with index BW/A 235.9%, H/A 220.5%, body weight/height (BW/H) 225.8%, and BMI/A 141.5%. Conclusion: Statistical analysis Independent samples t-test at the significance level ?=0.05 showed that there was a significant difference (p<0.05) in the teacher's ability to assess the nutritional status of children with the index BW/A, H/A, BW/H, and BMI/A in the control group with treatment after intervention. The teachers of early childhood education are always expected to make it a habit to monitor children's nutritional status using a pocketbook on child nutrition anthropometry that has been applied.
PENERAPAN TEKNOLOGI UNDERWATER AKUSTIK (FISH FINDER) TERHADAP POLA DISTRIBUSI VERTIKAL IKAN DI BAGAN PERAHU DESA PILOWO KABUPATEN PULAU MOROTAI
Authors: Alwi Djainudin , Nurafni Nurafni , Sofiati Titien , Kodobo M. Jihar 
Published: February 2022

Penggunaan teknologi akustik bawah air (Underwater Acoustic) khususnya fish finder belum banyak diterapkan terutama oleh nelayan dalam membantu mendeteksi keberadaan ikan. Penggunaan instrumen akustik pada bagan perahu dapat digunakan untuk mengetahui waktu kedatangan ikan pada bagan dan pola distribusi baik secara vertikal. Efektivitas dan intensitas pengoperasian waktu kedatangan ikan pada alat tangkap bagan. Tujuan dari penelitian ini menganalisis pola distribusi vertikal ikan pada areal bagan perahu berdasarkan umur bulan. Penelitian ini dilakukan diperairan desa Pilowo Kecamatan Morotai Selatan Kabupaten Pulau Morotai pada bulan Januari 2021. Teknik pengambilan data dengan menggunakan metode Eksperimental fishing. Data yang diperoleh di analisis secara deskriptif yang ditampilkan dalam bentuk grafik/gambar. Hasil penelitian menunjukan bahwa penggunaan fish finder pada pengoperasian alat tangkap bagan cukup efektif untuk membantu nelayan dalam mendekteksi gerombolan ikan dikolom perairan. Pola distribusi vertikal ikan dengan menggunakan teknologi fish finder pada alat tangkap bagan terlihat bervariasi sesuai fase umur bulan, waktu pengamatan, parameter lingkungan dan kedalaman perairan
Factors Associated with Exclusive Breastfeeding of Late Preterm Infants in Neonatal Hospital: Cross-Sectional Study
Authors: Prikhodko Evgeniia A. , Belyaeva Irina A. , Kruglyakov Andrey Yu. , Mikheeva Anna A. , Gorev Valeriy V. 
Published: February 2022

Background. Breast milk is the optimal nutrition for late preterm babies, but mothers of these babies frequently experience difficulties with breastfeeding associated with lactation onset and establishment.Objective. The aim of the study is to examine factors associated with successful breastfeeding of late preterm infants in neonatal hospital.Methods. The retrospective study included medical records of late preterm infants (gestational age of 34–36 weeks) admitted to neonatology department within one calendar year. Maternal and infant factors on exclusive breastfeeding were considered at hospital discharge. Exclusive breastfeeding was defined as absence of any other food or drink, even water, except breast milk (expressed or donor), whereas enteral fluid for rehydration, as well as drops and syrups (vitamins, minerals, medicines) were allowed. Determination of independent predictors was performed via multifactorial binary logistic regression.Results. 84 (41%) of children received exclusive breastfeeding at hospital discharge, others were on formula or mixed feeding. Multifactorial analysis has shown that gestational age of 36 weeks (compared to 34 weeks, odds ratio (OR) 2.16; 95% confidence interval (CI) 1.18–3.98) and breastfeeding onset in 6 first hours of life (OR 2.38; 95% CI 1.19–4.75) were associated with relatively high probability of exclusive breastfeeding at hospital discharge, and twins (OR 0.31; 95% DI 0.15–0.65) — with low probability.Conclusion. Breastfeeding of late preterm babies with maternal milk (expressed milk included) in the first hours of life positively affects the lactation establishment and the provision of exclusively breast milk to these patients in neonatal hospital. The risk group for early cessation of breastfeeding may include late premature infants with gestational age less than 36 weeks and twins.
Historical aspects and modern concepts in the treatment of patients with differentiated thyroid cancer, refractory to radioactive iodine therapy
Authors: Borodavina E. V. , Krylov V. V. , Isaev P. A. , Shurinov A. Yu. , Rodichev A. A. 
Published: February 2022

Radioiodine therapy for differentiated thyroid cancer has been used for a long time, mainly in patients of intermediate and high risk, as well as in the presence of distant metastases. However, about 30–40 % of patients are refractory to radioiodine therapy, which significantly worsens the prognosis. In patients with radioiodine-refractory differentiated thyroid cancer, therapy with targeted agents, primarily tyrosine kinase inhibitors, is indicated.This review addresses the criteria for refractoriness and criteria for prescription of targeted therapy, and presents the results of clinical studies of the targeted agents used. As of today, lenvatinib is the most well-known targeted agent. In particular. In SELECT trial lenvatinib demonstrated efficacy in terms of progression-free survival and overall survival in patients with radioiodine-refractory differentiated thyroid cancer. As a result, lenvatinib was included in the international and Russian clinical guidelines for the management of this group of patients as a drug of the 1st line of targeted therapy.
Analysis results of surgical treatment and chemoradiotherapy with assessment of prognostic factors in localy advanced laryngeal cancer
Authors: Radzhabova Z. A.‑G. , Kotov M. A. , Girshovich M. M. , Ponomareva O. I. , Kostromina E. V. , Radzhabova M. A. , Mitrofanov A. S. , Klimenko V. V. , Levchenko E. V. 
Published: February 2022

The study objective – to analyze the treatment results and prognostic factors of survival in patients with locally advanced laryngeal cancer who received surgical treatment and chemoradiotherapy.Materials and methods. The retrospective study included patients with locally advanced laryngeal cancer treated at the N. N. Petrov National medical Research Center of Oncology, Ministry of Health of Russia in the period from 2009 to 2018. The patients included in the study were divided into 2 equal groups (74 patients were included in each group) depending of treatment: surgery with postoperative radiation therapy combined with chemotherapy (group 1) and concurrent chemoradiation therapy and subsequent surgical treatment in case of incomplete response to treatment or disease progression (group 2). The endpoints of the study were general and relapse-free survival.Results. One hundred and forty-eight patients were included in the study: 74 patients in group 1 and 74 patients in the group 2. The median overall survival in the surgical treatment group was 45 months, in the chemoradiotherapy group – 44.6 months, and the overall 5-year survival for the group 1 and the group 2 were 39.3 (95 % confidence interval (CI) 26.1–59.2), and 59.2 % (95 % CI 45.3–77.2), respectively. The relapse-free 5-year survival rate for the surgical treatment group and the chemoradiotherapy group was 36.8 (95 % CI 25.1–53.8), and 53.9 % (95 % CI 40.7–71.4), respectively.Conclusion. There were no significant differences in overall and relapse-free survival. Metastatic lesion of the neck lymph nodes (N2–3), invasion of laryngeal cartilage, invasion of the thyroid gland and the spread of the tumor to the larynx are statistically significantly associated with lower overall and relapse-free survival.
Effects of nutritional support in cancer patients receiving chemotherapy
Authors: Galeeva E. V. , Stepanova A. M. , Kostin A. A. 
Published: February 2022

Introduction. Nutritional support is an important component of multimodal cancer therapy. It is well known that proper nutrition supplemented by necessary nutrients can support muscles and their function, reduce the incidence and severity of complications associated with cancer therapy, and facilitate recovery. Proper nutritional support is planned according to patient’s need for energy (30 kcal / kg body weight per day), protein (1.5 g protein / kg body weight per day), and eicosapentaenoic acid (2 g per day).Materials and methods. We analyzed the dynamics of nutritional status of 632 cancer patients treated in P.A. Herzen Moscow Oncology Research Institute – a branch of the National Medical Radiology Research Center, Ministry of Health of Russia between 2019 and 2021. Study participants were divided into two groups: experimental (n = 316) and control (n = 316). Patients in the experimental group received proper nutritional support. This study included patients with confirmed gastrointestinal cancers (esophageal and gastric), colon cancer, head and neck cancer, and lung cancer.Results. Nutritional therapy in the process of drug antitumor treatment has improved the trophological status of patients with tumors of the head and neck, lungs, upper gastrointestinal tract. As a result of the work, there was a tendency to increase the body weight of patients in these subgroups, whereas in the control group there was a statistically significant decrease in body weight compared to the initial indicators by 9.4; 9.5; 5.3 and 9.6 kg, respectively. Also, full clinical nutrition contributed to an increase in the level of total protein in patients with cancer of the upper gastrointestinal tract and colon and rectum by 4.0 and 3.7 g/l, respectively, at the level of statistical trend. The level of albumin significantly increased (by 6.6 g/l) only in patients with lung cancer.Improved nutritional status of patients during their systemic therapy ensured a 6 % reduction in the frequency of intercycle periods, a 0.2–3.4 % reduction in the need for dosage correction, and a 2.9–11.1 % increase in the completeness of cancer therapy stages (trend).Conclusion. Our findings suggest that additional specialized (oral or enteral) nutritional support during chemotherapy stabilizes body weight and its index, resulting, first of all, in improved tolerability of treatment.
Hubungan antara Durasi Tidur dengan Asupan Makan, Aktivitas Fisik dan Kejadian Obesitas Pada Mahasiswa Program Studi Pendidikan Dokter UIN Maulana Malik Ibrahim Malang
Authors: Rahmawati Ermin , Firdaningrum Nimas Eka , Agoes Achdiat 
Published: February 2022

Durasi tidur yang pendek merupakan masalah yang kerap dihadapi oleh mahasiswa kedokteran. Disisi lain, obesitas merupakan salah satu masalah gizi utama di dunia termasuk Indonesia, dengan salah satu faktor resiko yaitu gangguan fungsi tidur. Penelitian ini bertujuan untuk meneliti hubungan antara durasi tidur dengan asupan makan, aktivitas fisik dan kejadian obesitas pada mahasiswa PSPD UIN Maulana Malik Ibrahim Malang. Penelitian ini merupakan studi cross sectional dengan teknik cluster sampling. Sebanyak 78 mahasiswa PSPD UIN Maulana Malik Ibrahim Malang berpartisipasi sebagai responden penelitian ini. Durasi tidur diukur dengan menggunakan kuisioner Rerata Durasi Tidur dalam 1 minggu, asupan makan diukur dengan kuisioner 24 Hours Food Recall, aktivitas fisik diukur dengan kuisioner GPAQ (Global Physical Activity Questionnaire) dan kejadian obesitas dinilai dari BMI (Body Mass Index), BMI diukur dengan menggunakan timbangan berat badan dan tinggi badan SMIC ZT-120. Data yang diperoleh diolah mengggunakan statistik deskriptif dan inferensial, dengan uji analisis chi-square. Dari total 78 responden, didapatkan bahwa sebagian besar mahasiswa memiliki durasi tidur yang buruk (6 jam; 53,8%), sedangkan mahasiswa yang memiliki durasi tidur cukup (6 jam) sebesar 28,2% dan durasi tidur baik (7-9 jam) sebesar 17,9%. Hasil analisis chi-square menunjukkan bahwa durasi tidur memiliki hubungan yang signifikan dengan asupan makan (p-value= 0,000) dan kejadian obeistas (p-value= 0,000), tetapi durasi tidur tidak memiliki hubungan yang signifikan dengan aktivitas fisik (p-value= 0,171). Durasi tidur yang buruk memiliki hubungan dengan kejadian obesitas melalui asupan makan, tapi tidak dengan aktivitas fisik.Kata kunci : Kata kunci : Body Mass Index, Asupan Makan, Kejadian Obesitas, Aktivitas Fisik, Durasi Tidur
The Effectivity of Murottal Al-Qur’an Exposure to Spermatogenesis of Male Mice (Mus musculus) with stress
Authors: Dianti Meilina Ratna , Mazidah Lilik Khoiriyatul , Ari Indrawijaya Yen Yen , Inayatilah Fidia Rizkiah 
Published: February 2022

Introduction: Stress is the body's reaction to pressure from stressors; one of the stressors that can trigger stress is a noise stressor. Stress can disrupt the body's homeostasis system, one of the cycles of spermatogenesis. Murottal Al-Qur'an therapy listening can produce a response of relaxation and peace of mind to increase healing. Methods: The study was conducted on 25 healthy male mice aged 8-12 weeks grouped randomly into five groups. The positive control group is the normal group. The negative control group is given a 12-hour stressor. The treatment groups are given 12 hours and 1, 2, and 4 hours therapy. The treatment for each group was carried out for 21 days. Spermatogenesis of mice was observed through the number of primary spermatocytes cells and spermatid cells. It takes place during the preparation of testicular histology with Hematoxylin Eosin staining. Primary spermatocyte and spermatid counts were examined under a 40x magnification microscope. Results: Murottal Al-Qur'an therapy can affect the amount of primary spermatocyte cells (p-value = 0.000) and spermatids (p-value = 0,000) that are very significant. Conclusion: Murottal Al-Qur'an therapy can be used to increase the spermatogenesis of mice with stress. Keywords: Stress, Noise, Spermatogenesis, Murottal Al-Qur'an.
STRATEGI PENYEBARLUASAN ILMU HUKUM MELALUI SASTRA
Authors: Hapsari Murti Ayu , Murtini Murtini 
Published: February 2022

<p><em>Novels are one of the literary genres that utilize language. In this case, the use of language in literary or literature, according to Umar Kayam, is not about using it correctly or not, but rather whether or not that language appropriate for specific occasion. Likewise, legal science cannot separate itself from language in terms of its application. Language in law of legal filed has its own variety which often makes it difficult for people who are not directly involved in it to grasp its certain meanings. This is because language in law require that it can conveyed in a concrete, straightforward manner, so that it will not lead to many ambiguous interpretations. It can be said that the use of language form in these two domains is in very opposite direction. Novel written by Agus Sardjono, "Legal Research: A Novel on Legal Research Methods" tries to unravel these difficulties by using literary as tools specifically to facilitate students of university in understanding and applying legal research methods. This paper will further describe the novel in two perspectives; legal point of view and literary point of view. The novel "Legal Research" proves that literature is a very broad as a medium, that can be used to describe various field of expertise such as history, psychology, politics, including law.</em></p>
Taper Material Loss in Total Hip Replacements
Authors: McCarty Colin P. , Park Sang-Hyun , Ho Nathan C. , Sangiorgio Sophia N. , Ebramzadeh Edward 
Published: February 2022

Background:
Metal debris and corrosion products generated from the taper junctions of modular joint replacements have been recognized as contributors to failure. Therefore, understanding the factors associated with increased taper wear and corrosion is fundamental to improving implant performance.

Methods:
A cohort of 85 large-diameter metal-on-metal heads and cups retrieved at revision surgery, after 10 to 96 months of service, was evaluated. First, metrology was conducted to quantify head taper material loss and implant articular surface wear. Then, joint frictional moments for each retrieved head-and-cup pair were measured during 10 cycles of simulated physiological gait in a biomechanical model. Taper material loss was evaluated for correlations with frictional moments, articular wear, head diameter, head-cup clearance, and time in vivo.

Results:
Peak resultant frictional moments ranged from 9.1 to 26.3 Nm, averaging 17.3 ± 2.7 Nm. Fretting and corrosion damage during in vivo service resulted in material loss from the head tapers ranging between 0.04 and 25.57 mm3, compared with combined head and cup articular wear of 0.80 to 351.75 mm3 in this cohort. Taper material loss was not correlated with higher frictional moments (R = −0.20 to 0.11, p = 0.07 to 0.81). Higher frictional moments from axial rotation were correlated with higher head and cup wear (R = 0.33, p < 0.01). The correlation between taper material loss and head diameter was weak and did not reach statistical significance (R = 0.20, p = 0.07). Taper material loss was not correlated with nominal head-cup clearance (R = 0.06, p = 0.6). Finally, taper material loss increased significantly over time (R = 0.34, p < 0.01).

Conclusions:
Despite serious concerns regarding trunnionosis, volumes of head taper wear were generally lower than those of articular surface wear. There was no statistical correlation between taper wear and frictional moments. Therefore, the results suggest that high friction in metal-on-metal implants does not contribute to higher material loss at the head taper, despite high bending moments.

Clinical Relevance:
The amount of metal debris and corrosion products from taper junctions of the joint arthroplasties, widely recognized as an insidious cause of failure, was not correlated with joint frictional moments. Multiple factors affect taper wear: implant design, material, size, surface finish, and patient weight and activity level. However, in the present cohort, high friction of metal-on-metal total hip replacements likely did not contribute to increased volume of material loss at taper interfaces, despite increased moments at the locations of taper material loss.
Prevalence of Oncogenic Human Papillomavirus in Pregnant Adolescents, Association With Colpocytological Changes, Risk Factors and Obstetric Outcomes
Authors: de Souza Henrique Diório , Waismann Adriana Lippi , Diório Giselle Rodrigues Mota , Peres Stela Verzinhasse , Francisco Rossana Pulcineli Vieira , Galletta Marco Aurélio Knippel 
Published: February 2022

Abstract
Purpose: We aim to carry out an investigation on the impact of cervical oncogenic human papillomavirus (HPV) infection in pregnant adolescents, to clarify the prevalence and risk factors, considering the importance and lack of data on this topic in Brazil.Methods: A cross-sectional study was conducted with adolescents receiving specialized prenatal care in a tertiary hospital in São Paulo, Brazil. On the first prenatal visit, were performed an oncotic colpocytological exam and an oncogenic-HPV assessment of the uterine cervix. We sought the association these exams with demographic and obstetric variables.Results: A total of 303 pregnant adolescents whose mean age was 15.30 ± 1.22 years comprised the study subjects. The prevalence of high-risk HPV cervical infection was 50.50%. Multivariate analysis revealed that a large number of partners in their lifetime (OR=1.268) and having a religion (OR=2.054) were risk factors for oncogenic HPV-caused cervical infection, while schooling appeared as a protective factor (OR=0.847). There was an association between Oncogenic HPV infection and colpocytological alterations, reaching almost 30% of patients. There was no association between Oncogenic HPV infection and obstetric outcomesConclusion: The prevalence found is one of the highest in Brazil and worldwide. A greater number of partners during their lifetime and having religion were detected as possible factors associated with cervical HPV infection. The findings of this study reinforce the need to implement measures of health education and prevention capable of modifying the incidence of cytopathological cervical lesions and of uterine cervix cancer in this population.