bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co je to dobré rajče: Případová studie hodnocení v praxi
Authors: Heuts Frank , Mol Annemarie , Synek Michal 
Published: June 2022

As a contribution to the field of valuation studies this article lays out a number of lessons that follow from an exploratory inquiry into ‘good tomatoes’. We held interviews with tomato experts (developers, growers, sellers, processors, professional cooks and so-called consumers) in the Netherlands and analysed the transcriptions carefully. Grouping our informants’ concerns with tomatoes into clusters, we differentiate between five registers of valuing. These have to do with money, handling, historical time, what it is to be natural, and sensual appeal. There are tensions between and within these registers, that lead to clashes and compromises. Accordingly, valuing tomatoes does not fit into inclusive formal schemes. Neither is it simply a matter of making judgements. Our informants told us how they know whether a tomato is good, but also revealed what they do to make tomatoes good. Their valuing includes activities such as pruning tomato plants and preparing tomato dishes. But if such activities are meant to make tomatoes good, success is never guaranteed. This prompts us to import the notion of care. Care does not offer control, but involves sustained and respectful tinkering towards improvement. Which is not to say in the end the tomatoes our informants care for are good. In the end these tomatoes get eaten. And while eating performs tomatoes as ‘good to eat’, it also finishes them off. Valuing may lead on to destruction. An important lesson for valuation studies indeed.
Prevalence, Predictors, and Oncologic Outcomes of Pelvic Organ Involvement in Women Undergoing Radical Cystectomy
Authors: Avulova Svetlana , Benidir Tarik , Cheville John C. , Packiam Vignesh T. , Shah Paras , Frank Igor , Tollefson Matthew K. , Thompson R. Houston , Karnes R. Jeffrey , Thapa Prabin , Kulkarni Girish , Boorjian Stephen A. 
Published: June 2022

Context.—
In women, radical cystectomy includes removal of the bladder, uterus, fallopian tubes, ovaries, and anterior vaginal wall, yet contiguous extension of urothelial carcinoma to all pelvic organs is rare and routine removal may be unnecessary.

Objective.—
To study pelvic organ involvement in women at radical cystectomy and investigate oncologic outcomes.

Design.—
Women with bladder cancer who underwent radical cystectomy at the Mayo Clinic and University of Toronto (1980–2018) were evaluated. Cancer-specific survival (CSS) was estimated with the Kaplan-Meier method; comparisons were made with the log-rank test. Associations with CSS were evaluated with Cox proportional hazard modeling.

Results.—
A total of 70 women with pT4a and 83 with pT3b cancer were studied. Organs involved were vagina (n = 41 of 70; 58.6%), uterus (n = 26 of 54; 48.1%), cervix (n = 15 of 54; 27.8%), fallopian tubes (n = 10 of 58; 17.2%), and ovaries (n = 7 of 58; 12.1%); 22 of 58 patients (37.9%) had &gt;1 organ involved. Of 70 with pT4a cancer, 64 were available for survival analysis by 3 pelvic organ groups: vaginal only, vaginal and/or cervical/uterine, and vaginal and/or cervical/uterine and/or fallopian tubes/ovarian involvement. Three-year CSS for vaginal involvement only was 39%; it was 14% if cervical/uterine involvement, and &lt;1% if fallopian tube/ovarian involvement was included (P = .02). Among 20 women with pT4aN0/Nx and vaginal involvement only, 3-year CSS for vaginal involvement was 50%, whereas among 48 women with pT3bN0/Nx cancer, 3-year CSS was 58%, P = .70.

Conclusions.—
Isolated vaginal involvement should be separated from uterine and/or adnexal extension of urothelial carcinoma at pathologic staging. Direct ovarian extension is rare and routine removal may be unnecessary.
La fábrica textil de los hermanos Ríos Seguí de Llíria (1929-1974): un espacio de mujeres
Authors: Castillo Mas María Amparo 
Published: June 2022

En 1929 en el municipio de Llíria (Valencia), la instauración de una fábrica textil transformó la trayectoria de vida de centenares de mujeres, así como el urbanismo, la demografía y la economía de la localidad.
La fábrica permaneció abierta hasta el año 1974, contaba con una plantilla mixta, aunque la fuerza mayoritaria del trabajo recaía en las mujeres, quienes se encontraban tensionadas entre un mundo que se modernizaba y que las incluía en las relaciones contractuales, dotándolas de cierta autonomía y la sociedad que marcaba pautas de conductas determinada por los roles de género. Este artículo busca evidenciar y dar a conocer, la importancia que en el siglo XX tuvo la fábrica de los hermanos Ríos Seguí para la sociedad valenciana.
Transmission networks of SARS-CoV-2 in Coastal Kenya during the first two waves: A retrospective genomic study
Authors: Agoti Charles N , Ochola-Oyier Lynette Isabella , Dellicour Simon , Mohammed Khadija Said , Lambisia Arnold W , de Laurent Zaydah R , Morobe John M , Mburu Maureen W , Omuoyo Donwilliams O , Ongera Edidah M , Ndwiga Leonard , Maitha Eric , Kitole Benson , Suleiman Thani , Mwakinangu Mohamed , Nyambu John K , Otieno John , Salim Barke , Musyoki Jennifer , Murunga Nickson , Otieno Edward , Kiiru John N , Kasera Kadondi , Amoth Patrick , Mwangangi Mercy , Aman Rashid , Kinyanjui Samson , Warimwe George , Phan My , Agweyu Ambrose , Cotten Matthew , Barasa Edwine , Tsofa Benjamin , Nokes D James , Bejon Philip , Githinji George 
Published: June 2022

Background:Detailed understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) regional transmission networks within sub-Saharan Africa is key for guiding local public health interventions against the pandemic.Methods:Here, we analysed 1139 SARS-CoV-2 genomes from positive samples collected between March 2020 and February 2021 across six counties of Coastal Kenya (Mombasa, Kilifi, Taita Taveta, Kwale, Tana River, and Lamu) to infer virus introductions and local transmission patterns during the first two waves of infections. Virus importations were inferred using ancestral state reconstruction, and virus dispersal between counties was estimated using discrete phylogeographic analysis.Results:During Wave 1, 23 distinct Pango lineages were detected across the six counties, while during Wave 2, 29 lineages were detected; 9 of which occurred in both waves and 4 seemed to be Kenya specific (B.1.530, B.1.549, B.1.596.1, and N.8). Most of the sequenced infections belonged to lineage B.1 (n = 723, 63%), which predominated in both Wave 1 (73%, followed by lineages N.8 [6%] and B.1.1 [6%]) and Wave 2 (56%, followed by lineages B.1.549 [21%] and B.1.530 [5%]). Over the study period, we estimated 280 SARS-CoV-2 virus importations into Coastal Kenya. Mombasa City, a vital tourist and commercial centre for the region, was a major route for virus imports, most of which occurred during Wave 1, when many Coronavirus Disease 2019 (COVID-19) government restrictions were still in force. In Wave 2, inter-county transmission predominated, resulting in the emergence of local transmission chains and diversity.Conclusions:Our analysis supports moving COVID-19 control strategies in the region from a focus on international travel to strategies that will reduce local transmission.Funding:This work was funded by The Wellcome (grant numbers: 220985, 203077/Z/16/Z, 220977/Z/20/Z, and 222574/Z/21/Z) and the National Institute for Health and Care Research (NIHR), project references: 17/63/and 16/136/33 using UK Aid from the UK government to support global health research, The UK Foreign, Commonwealth and Development Office. The views expressed in this publication are those of the author(s) and not necessarily those of the funding agencies.
Body mass index and postoperative mortality in patients undergoing coronary artery bypass graft surgery plus valve replacement: a retrospective cohort study
Authors: Dai Chun , Xu Hongbo , Chu Tianshu , Cao Boyang , Ge Jianjun 
Published: June 2022

BackgroundThe relationship between body mass index (BMI) and postoperative mortality in patients who undergo coronary artery bypass graft (CABG) surgery plus valve replacement is uncertain. We aimed to investigate the association between body mass index (BMI) and postoperative mortality among patients who simultaneously underwent both CABG surgery plus valve replacement.MethodsWe retrospectively analyzed 1976 patients who underwent CABG surgery at our hospital between January 2017 and April 2021, including 202 patients who underwent valve replacement surgery during the same period. We analyzed the relationship between BMI and postoperative mortality. The relationship between BMI and postoperative mortality was assessed using smooth curve fitting and a Multiple logistic regression model.ResultsThe results of smoothing curve fitting showed that BMI and postoperative mortality had a non-linear relationship, and the resulting curve exhibited a two-stage change and a breakpoint. Postoperative mortality is higher in patients that have a body mass index above 25 kg/m2compared to patients having a body mass index between 18 and 25 kg/m2.ConclusionsOur study found a non-linear relationship between BMI and postoperative mortality in patients undergoing CABG plus valve replacement after adjusting for potential confounders. The causal relationship between BMI and postoperative mortality still requires further investigations.
Prevalence and Risk Factors of Urinary Schistosomiasis among School-Aged Children in Devego Sub-Municipal, Ketu North Municipality, Volta Region, Ghana
Authors: Kankpetinge Christopher , Tekpor David , Dongdem Anthony Zunuo , Frimpong Kwasi , Odonkor Stephen 
Published: June 2022

Background: Schistosomiasis affects an estimated 250 million people worldwide, with 200,000 people dying each year. Despite success in managing the disease, data on its prevalence in non-endemic areas is rare. This study assessed the prevalence and risk factors of urogenital schistosomiasis among people in the Devego sub-municipality of the Ketu North Municipal Volta region, Ghana.
Methods: A cross-sectional study design was conducted among 335 respondents. Data was collected using a semi-structured questionnaire. Urine samples were examined microscopically to identify S. haematobium ova. Categorical data was analyzed and presented as percentages or frequencies. Means, medians and standard deviations were used to summarize the continuous variables. Chi-square/Fishers Exact test was used to determine the associations between the independent and dependent variables and considered significant if P-value was less than 0.05.
Results: The study found 34.6% (116/335) prevalence rate of urinary schistosomiasis among the 335 participants studied. The prevalence rate was 58.6% (68/116) in male respondents and 41.4% (48/116) among female respondents. Respondents aged 11-15 years recorded the highest (41.4%) prevalence. Major risk factors associated with urinary schistosomiasis were; swimming, fetching of water, bathing and washing of cloths ((X2=21.207, P-value < .02); frequency of exposure to fresh water (X2 = 14.684, P = .005, CL = 95%).
Conclusion: Urinary schistosomiasis is common in remote communities with fresh water sources. Chemoprevention should be extended to schistosomiasis non-endemic communities with fresh water sources.
Percutaneous Release of Trigger Finger
Authors: Elfiky Ahmed Samir , Romeih Mohamed Abd El Hamed , Mougahed Abdel Hafez Abd El Hafez , Gharbo Nabil Omar 
Published: June 2022

Background: Trigger finger (sometimes referred to as stenosing tenosynovitis) is a mechanical impingement of the hand's flexor tendon. This ailment is a frequent source of hand pain, discomfort, and impairment, since it may reduce the afflicted finger's range of motion. This research seeks to investigate the outcomes of surgical release of trigger finger by percutaneous method.
Methods: This prospective study that included 21 adult patients aged > 16 years and diagnosed by clinical assessment by percutaneous release of A1 pulley of the diseased finger with history of triggering for at least 3 months and failure of previous conservative treatments. Each case was followed up for 6 weeks after enrolment.
Results: Excellent outcomes were significantly increased in cases with one finger affection than cases with multi finger affection (P =0.025). There was no significant variance in the outcomes among patients with right and left sided hands. Patients with excellent outcome had shorter duration of symptoms than patients with good and poor outcomes (P =0.032).
Conclusions: Excellent outcomes were significantly increased in cases with office work than cases with manual work and in patients with one finger affection than patients with multi finger affection.
A phase space model of a Versa HD linear accelerator for application to Monte Carlo dose calculation in a real‐time adaptive workflow
Authors: Bedford James L. , Nilawar Rahul , Nill Simeon , Oelfke Uwe 
Published: June 2022

AbstractPurposeThis study aims to develop and validate a simple geometric model of the accelerator head, from which a particle phase space can be calculated for application to fast Monte Carlo dose calculation in real‐time adaptive photon radiotherapy. With this objective in view, the study investigates whether the phase space model can facilitate dose calculations which are compatible with those of a commercial treatment planning system, for convenient interoperability.Materials and methodsA dual‐source model of the head of a Versa HD accelerator (Elekta AB, Stockholm, Sweden) was created. The model used parameters chosen to be compatible with those of 6‐MV flattened and 6‐MV flattening filter‐free photon beams in the RayStation treatment planning system (RaySearch Laboratories, Stockholm, Sweden). The phase space model was used to calculate a photon phase space for several treatment plans, and the resulting phase space was applied to the Dose Planning Method (DPM) Monte Carlo dose calculation algorithm. Simple fields and intensity‐modulated radiation therapy (IMRT) treatment plans for prostate and lung were calculated for benchmarking purposes and compared with the convolution‐superposition dose calculation within RayStation.ResultsFor simple square fields in a water phantom, the calculated dose distribution agrees to within ±2% with that from the commercial treatment planning system, except in the buildup region, where the DPM code does not model the electron contamination. For IMRT plans of prostate and lung, agreements of ±2% and ±6%, respectively, are found, with slightly larger differences in the high dose gradients.ConclusionsThe phase space model presented allows convenient calculation of a phase space for application to Monte Carlo dose calculation, with straightforward translation of beam parameters from the RayStation beam model. This provides a basis on which to develop dose calculation in a real‐time adaptive setting.
Nonhalogenated Dual‐Slot‐Die Processing Enables High‐Efficiency Organic Solar Cells
Authors: Xue Jingwei , Zhao Heng , Lin Baojun , Wang Yilin , Zhu Qinglian , Lu Guanyu , Wu Baohua , Bi Zhaozhao , Zhou Xiaobo , Zhao Chao , Lu Guanghao , Zhou Ke , Ma Wei 
Published: June 2022

AbstractOrganic solar cells (OSCs) are promising candidates for next‐generation photovoltaic technologies, with their power conversion efficiencies (PCEs) reaching 19%. However, the typically used spin‐coating method, toxic halogenated processing solvents, and the conventional bulk‐heterojunction (BHJ), which causes excessive charge recombination, hamper the commercialization and further efficiency promotion of OSCs. Here, a simple but effective dual‐slot‐die sequential processing (DSDS) strategy is proposed to address the above issues by achieving a continuous solution supply, avoiding the solubility limit of the nonhalogen solvents, and creating a graded‐BHJ morphology. As a result, an excellent PCE of 17.07% is obtained with the device processed with o‐xylene in an open‐air environment with no post‐treatment required, while a PCE of over 14% is preserved in a wide range of active‐layer thickness. The unique film‐formation mechanism is further identified during the DSDS processing, which suggests the formation of the graded‐BHJ morphology by the mutual diffusion between the donor and acceptor and the subsequent progressive aggregation. The graded‐BHJ structure leads to improved charge transport, inhibited charge recombination, and thus an excellent PCE. Therefore, the newly developed DSDS approach can effectively contribute to the realm of high‐efficiency and eco‐friendly OSCs, which can also possibly be generalized to other organic photoelectric devices.
Pd(II)‐Catalyzed Asymmetric Addition of Arylboronic Acids to Aliphatic N‐Carbamoyl Hydrazones
Authors: Alberca Saúl , Velázquez Marta , Trujillo‐Sierra José , Iglesias‐Sigüenza Javier , Fernández Rosario , Lassaletta José M. , Monge David 
Published: June 2022

AbstractCatalysts generated by combinations of Pd(TFA)2 and pyridine‐hydrazone ligands have been applied to 1,2 addition of arylboronic acids to aliphatic N‐carbamoyl (Cbz) hydrazones, affording protected α‐aryl monoalkylhydrazines with high enantioselectivities (37‐99% ee). Subsequent removal of the benzyloxy carbonyl protecting group provides a direct entry to free monosubstituted hydrazines, key building blocks for the synthesis of appealing 1,2‐diaza‐heterocycles, aminoacid derived hydrazides and other pharmacophores thereof.magnified image
Machine Learning Accelerates Molten Salt Simulations: Thermal Conductivity of MgCl2‐NaCl Eutectic
Authors: Liang Wenshuo , Lu Guimin , Yu Jianguo 
Published: June 2022

AbstractThe marriage of ab initio calculations and machine learning (ML) methods exhibits bright application prospects in interatomic potential development. In this work, a concurrent learning scheme is implemented to automatically generate ML interatomic potential for the MgCl2‐NaCl eutectic. This scheme allows to train ML interatomic potential with training datasets approximately four times smaller than that of previous work, which significantly reduces the computational cost. The learned ML interatomic potential is used to accelerate the ab initio estimation of the properties of MgCl2‐NaCl eutectic, thermal conductivity in particular. With the learned models, simulations are conducted on multiple system sizes (1464–4392 atoms) and a wide temperature range (773–1073 K). The impact of the finite‐size effect on simulated thermal conductivity and derived size‐independent thermal conductivity is carefully investigated. The simulated thermal conductivities decrease with temperature and are in the range 0.469–0.538 W m−1 K−1 at 773–1073 K, which is in reasonable agreement with the literature data. Overall, the training scheme and the learned potential have produced reliable and satisfactory results, and promise to open up new avenues in the computational modeling of molten salts.
Synthesis of Glycerol Carbonate from Glycerol and CO2 Using CaO as a Dehydrating Agent
Authors: Takeuchi Katsuhiko , Matsumoto Kazuhiro , Fukaya Norihisa , Sato Kazuhiko , Choi Jun‐Chul 
Published: June 2022

AbstractGlycerol carbonate, a high value‐added chemical, is produced from glycerol, a surplus biomass byproduct of biodiesel production, and carbon dioxide, an inexhaustible raw material. In this study, calcium oxide (CaO) was used as a regenerable dehydrating agent, and Zn(OTf)2/1,10‐phenanthroline was used as the catalyst. Stirring with a common magnetic stirrer bar was found to be unsuitable for the reaction, owing to the solidification of calcium components after dehydration. However, mechanical stirring effectively resolves this issue and produces a high yield. The only byproduct of the reaction is H2O, since CaO is regenerable. In addition, because the carbon atoms of biomass‐derived glycerol are obtained from CO2 fixed by plant photosynthesis, all the carbon atoms of glycerol carbonate can be said to be derived from CO2. This approach can be used for the syntheses of other cyclic carbonates as well.
DMSO as C1 Source under Metal‐ and Oxidant‐free Conditions: NH4SCN‐mediated Synthesis of Quinazolinone and Dihydroquinazolin‐4(1H)‐one Derivatives
Authors: Govindan Karthick , Jayaram Alageswaran , Qi Chen Nian , Duraisamy Tamilselvan , Lin Wei‐Yu 
Published: June 2022

AbstractA new and efficient strategy for the development of quinazolinones and dihydroquinazolin‐4(1H)‐ones promoted by ammonium thiocyanate is reported. Most remarkably, dimethyl sulfoxide is used for solvent as well as methine and bridged methylene source to obtain a wide variety of new N, N‐disubstituted 2,3‐ dihydroquinazolin‐4(1H)‐ones. This transformation possesses significant advantages such as metal‐ and oxidant‐free, non‐acidic medium, simple condition, good functional group tolerance and broad substrate scope. Besides, this process could be readily scaled up and applied to drug molecules synthesis.
Vergleichende Evaluierung lichtgetriebener Katalyse: Ein Rahmenkonzept für das standardisierte Berichten von Daten**
Authors: Ziegenbalg Dirk , Pannwitz Andrea , Rau Sven , Dietzek‐Ivanšić Benjamin , Streb Carsten 
Published: June 2022

AbstractLichtgetriebene homogene und heterogene Katalyse erfordern ein komplexes Zusammenspiel von Lichtabsorption, Ladungstrennung, Ladungstransfer und katalytischem Umsatz. Optische und Bestrahlungsparameter sowie reaktionstechnische Aspekte spielen eine wichtige Rolle bei der Kontrolle der katalytischen Leistung. Diese Vielzahl von Faktoren erschwert den objektiven Vergleich lichtgetriebener Katalysatoren und die unvoreingenommene Leistungsbewertung. Dieser Artikel unterstreicht die Bedeutung der Erfassung und Dokumentation experimenteller Daten in homogener und heterogener lichtgetriebener Katalyse. Dazu wird eine kritische Analyse der Vorteile und Grenzen üblicherweise verwendeter experimenteller Indikatoren vorgenommen. Datenerfassung und ‐dokumentation nach den FAIR‐Prinzipien werden im Zusammenhang mit zukünftiger automatisierter Datenanalyse diskutiert. Wir schlagen einen Mindestdatensatz als Grundlage für eine einheitliche Erfassung und Dokumentation von experimentellen Daten in der homogenen und heterogenen lichtgetriebenen Katalyse vor. Die Forschungscommunity wird ermutigt, die zukünftige Entwicklung dieser Parameterliste im Rahmen eines offenen Online‐Repository zu unterstützen.
Sulfur‐Doped Quintuple [9]Helicene with Azacorannulene as Core
Authors: Wu Yin‐Fu , Ying Si‐Wei , Liao Song‐Di , Zhang Ling , Du Jun‐Jie , Chen Bin‐Wen , Tian Han‐Rui , Xie Fang‐Fang , Xu Han , Deng Shun‐Liu , Zhang Qianyan , Xie Su‐Yuan , Zheng Lan‐Sun 
Published: June 2022

AbstractHerein, a hetero(S,N)‐quintuple [9]helicene (SNQ9H) molecule with an azacorannulene core was synthesized, currently representing the highest hetero‐helicene reported in the field of multiple [n]helicenes. X‐ray crystallography indicated thatSNQ9Hincludes not only a propeller‐shaped conformerSNQ9H‐1, but also an unforeseen quasi‐propeller‐shaped conformerSNQ9H‐2. Different conformers were observed for the first time in multiple [n≥9]helicenes, likely owing to the doping of heteroatomic sulfurs in the helical skeletons. Remarkably, the ratio ofSNQ9H‐1toSNQ9H‐2can be regulated in situ by the reaction temperature. Experimental studies on the photophysical and redox properties ofSNQ9Hand theoretical calculations clearly demonstrated that the electronic structures ofSNQ9Hdepend on their molecular conformations. The strategy of introducing heteroatomic sulfurs into the helical skeleton may be useful in constructing various conformers of higher multiple [n]helicenes in the future.