bluuebunny/crossref_metadata_2025_split huggingface dataset:
Best of ARM: Evaluating engagement in multisector community health networks: The case of tribal organizations
Authors: Owsley Kelsey M. , Bauer Kyla L. , Mays Glen P. 
Published: May 2022

AbstractObjectiveTo quantify variation in public health system engagement with tribal organizations across a national sample of communities and to identify predictors of engagement.Data SourcesWe used 2018 National Longitudinal Survey of Public Health Systems data, a nationally representative cohort of the US public health systems.Study DesignSocial network analysis measures were computed to indicate the extent of tribal organization participation in public health networks and to understand the sectors and social services that engage with tribal organizations in public health activities. Two‐part regression models estimated predictors of tribal engagement.Data CollectionA stratified random sample of local public health agencies was surveyed, yielding 574 respondents. An additional cohort of oversampled respondents was also surveyed to include jurisdictions from the entire state upon the request of their respective state health departments (n = 154). Analyses were restricted to jurisdictions with a nearby American Indian and Alaska Native (AI/AN) serving health facility, yielding a final sample size of 258 local public health systems.Principal FindingsWhen an AI/AN serving health facility was present in the region, tribal organizations participated in 28% of public health networks and 9% of implemented public health activities. Networks with tribal engagement were more comprehensive in terms of the breadth of sectors and social services participating in the network and the scope of public health activities implemented relative to networks without tribal engagement. The likelihood of tribal engagement increased significantly with the size of the AI/AN population, the presence of a tribal facility with Indian Health Service funding in the region, and geographic proximity to reservation land (p < 0.10).ConclusionsThe vast majority of public health networks do not report engagement with tribal organizations. Even when AI/AN serving health facilities are present, reported engagement of tribal organizations remains low.
Pleural decompression procedural safety for traumatic pneumothorax and haemothorax: Kelly clamps versus fine artery forceps
Authors: Fitzgerald Mark , Allen Thomas , Bai Shifeng , Mitra Biswadev , Chiu Wing , Helsloot Dries , Groombridge Chris , Mathew Joseph , Kim Yesul 
Published: May 2022

AbstractObjectiveThe present study aimed to determine the difference in force required to puncture simulated pleura comparing Kelly clamps to fine artery forceps. The treatment of symptomatic traumatic pneumothorax and haemothorax involves puncture of the parietal pleura to allow decompression. This is usually performed using Kelly clamps or fine artery forceps. Over‐puncture pulmonary injury risk increases with the force used.MethodsAn experienced single operator performed puncturing of simulated parietal pleura on a thoracic mannequin while wearing a force sensor under gloves. The force imparted at the device tip onto the parietal pleura was estimated by subtracting the force required to hold the device from the total force. Outcome variables were the total maximum force and force imparted by the device.ResultsThere were 11 simulated procedures completed, seven using Kelly clamps and four using fine artery forceps. After subtracting the force required to hold the chosen forceps, the median value of pleural puncture force using Kelly clamps was 52.91 N (IQR 36.68–63.56) and 10.70 N (IQR 7.64–26.56) using fine artery forceps (P = 0.006).ConclusionA significantly increased force was required to puncture simulated parietal pleura using Kelly clamps compared to fine artery forceps. This higher puncture force will be associated with increased instrument acceleration at the time of pleural puncture, which may result in an increased risk of injury to the underlying lung. Based on these data, clinicians may reduce the risk of pulmonary injury by using fine artery forceps rather than Kelly clamps when performing pleural decompression.
Motivating Corporate Sustainability Research in Management Accounting Through the Lens of Paradox Theory*
Authors: Pencle Nadra 
Published: May 2022

ABSTRACTOrganizational leaders identify corporate sustainability as a complicated and urgent business imperative that their organizations face. The management accountant's role is to help develop accounting systems to measure and report corporate sustainability, yet several factors contribute to the contemporary management accountant's challenges in satisfying stakeholder demands to integrate sustainability into their practices and operations. Like sustainability, the tenets of paradox theory revolve around salient interdependent tensions with contradictions that persist across time. Therefore, I propose paradox theory as an alternative to the business case framing that currently dominates sustainability decision‐making. In this paper, I synthesize the existing literature at the intersection of management accounting, corporate sustainability, and paradox theory. My research also unearths a new paradox, one currently absent from the literature: the corporate sustainability temporal paradox. Finally, I offer a set of theory‐based research questions geared toward moving beyond business case thinking in accounting corporate sustainability research.
Dissipation of seabird‐derived nutrients in a terrestrial insular trophic web
Authors: Gaiotto Juliana Vallim , Nunes Guilherme Tavares , Bugoni Leandro 
Published: May 2022

AbstractHighly mobile organisms can transport nutrients and energy among distinct ecosystems, such as between oceanic foraging areas and terrestrial breeding sites. Seabirds are great nutrient carriers and potentially play a key role in the maintenance of trophic webs on islands. In this study, we assessed three dimensions of marine nutrient dissipation—horizontal, temporal and vertical—on the tropical Meio Island of Fernando de Noronha Archipelago, Brazil. For this, C3 and C4 plants, ants and spiders found in a 100 m long transect between colonies of masked (Sula dactylatra) and red‐footed boobies (Sula sula) were sampled during the rainy (the masked booby breeding period) and dry seasons (the red‐footed booby breeding period). The marine contribution to the terrestrial trophic web was analysed using Bayesian mixing models from a carbon and nitrogen stable isotope data set. The main findings indicate that marine nutrients in the terrestrial trophic web dissipated horizontally as the distance from the colony increased, which was more marked during the rainy season. On the vertical axis, the relative contribution of marine nutrients in terrestrial consumers was strongly related to food habits but not necessarily to the trophic level, dissipating rather than increasing, due to variable omnivory and the use of terrestrial food sources. The breeding strategy of the masked booby (i.e. incubating eggs on the ground), in addition to a larger body size and larger colony, could produce a more concentrated pulse of nutrients in comparison to seabirds nesting sparsely on trees, contributing more efficiently to the enrichment of marine nutrients on land. The importance of seabirds for the maintenance of interconnected ecosystems has been demonstrated, and the role of marine‐derived nutrients in the enrichment of nutrient‐poor tropical islands.
Long‐term results of different surgical options in the management of solitary enchondroma
Authors: Karaytuğ Kayahan , Alpan Buğra , Bayram Serkan , Valiyev Natig , Bilgiç Bilge , Özger Harzem 
Published: May 2022

AbstractBackgroundsWe aimed to compare the average 10‐year results of patients treated with three different surgical methods, that is, extended curettage, extended curettage with grafting and extended curettage with cementation for the management of solitary enchondromas.MethodsTwo hundreds and three patients with a solitary enchondroma who underwent surgery at our department between 1990 and 2015 were evaluated retrospectively. Only extended curettage was performed in Group A (n: 75), extended curettage with grafting with autologous bone graft from the iliac crest in Group B (n: 58), and extended curettage with bone cement in Group C (n: 70). Surgical complications and recurrence were analysed and compared between these groups.ResultsNo significant differences were noted among the groups in terms of gender (P = 0.654), age (P = 0.264) and follow‐up duration (P = 0.919). The mean follow‐up period in all groups was 122.9 ± 39 (range: 60–271) months. In addition to curettage and cementation, three patients received mechanical support with plate screws because of fracture risk. One patient in the extended curettage with grafting group had surgical site infection that was treated with simple debridement and antibiotherapy. One patient in the extended curettage group had lost motions of the proximal interphalangeal joint, which was treated with aggressive physiotherapy.ConclusionWe compared the average 10‐year results of patients treated with three surgical options, namely, extended curettage, extended curettage with grafting, and extended curettage with cementation and no difference was found among the groups in local control of solitary enchondromas.
Dining on the dead in the deep: Active NH4+ excretion via Na+/H+(NH4+) exchange in the highly ammonia tolerant Pacific hagfish, Eptatretus stoutii
Authors: Clifford Alexander M. , Wilkie Michael P. , Edwards Susan L. , Tresguerres Martin , Goss Greg G. 
Published: May 2022

AbstractAimPacific hagfish are exceptionally tolerant to high environmental ammonia (HEA). Here, we elucidated a cellular mechanism that enables hagfish to actively excrete ammonia against steep ammonia gradients expected to be found inside a decomposing whale carcass.MethodsHagfish were exposed to varying concentrations of HEA in the presence or absence of environmental Na+, while plasma ammonia levels were tracked. 14C‐methylammonium was used as a proxy for NH4+ to measure efflux in whole animals and in isolated gill pouches; the latter allowed us to assess the effects of amiloride specifically on Na+/H+ exchangers (NHEs) in gill cells. Western blotting and immunohistochemistry were utilized to evaluate the abundance and sub‐cellular localization of Rhesus glycoprotein (Rh) channels in the response to HEA.ResultsHagfish actively excreted NH4+ against steep inwardly directed ENH4+ (ΔENH4+ ~ 35 mV) and pNH3 (ΔpNH3 ~ 2000 μtorr) gradients. Active NH4+ excretion and plasma ammonia hypo‐regulation were contingent on the presence of environmental Na+, indicating a Na+/NH4+ exchange mechanism. Active NH4+ excretion across isolated gill pouches was amiloride‐sensitive. Exposure to HEA resulted in decreased abundance of Rh channels in the apical membrane of gill ionocytes.ConclusionsDuring HEA exposure, hagfish can actively excrete ammonia against a steep concentration gradient using apical NHEs energized by Na+‐K+‐ATPase in gill ionocytes. Additionally, apical Rh channels are removed from the apical membrane, presumably to reduce ammonia loading from the environment. We suggest that this mechanism allows hagfish to maintain tolerable ammonia levels while feeding inside decomposing carrion, allowing them to exploit nutrient‐rich food‐falls.
Uniportal thoracoscopic lateral and posterior basal segmentectomy using intersegmental tunneling: Comparison with multiportal approach
Authors: Matsuura Natsumi , Igai Hitoshi , Kamiyoshihara Mitsuhiro 
Published: May 2022

AbstractThoracoscopic lateral and posterior basal (S9 + 10) segmentectomy (or S10 segmentectomy) is one of the most technically challenging anatomical segmentectomies. We have used “intersegmental tunneling” in the multiportal approach, and we now apply this with a little ingenuity in the uniportal approach. However, because of interference between instruments and the limited insertion angles in the uniportal approach, complex segmentectomies such as S9 + 10 or S10 become even more difficult. The perioperative outcomes were compared between uniportal and multiportal thoracoscopic lateral and posterior basal segmentecomy using intersegmental tunneling. There were no significant differences between the groups in patient characteristics and perioperative outcomes other than operation time, which was significantly shorter in the uniportal group than in the multiportal group (169 ± 21 vs 216 ± 34 min, P = .011). Thoracoscopic S9 + 10 (S10) segmentectomy can be safely performed through the uniportal approach without any difficulties using an intersegmental tunneling method and adding a little ingenuity.
Victorian evolution of inherited retinal diseases natural history registry (VENTURE study): Rationale, methodology and initial participant characteristics
Authors: Britten‐Jones Alexis Ceecee , O'Hare Fleur , Edwards Thomas L. , Ayton Lauren N. ,   the VENTURE Study Consortium
Published: May 2022

AbstractBackgroundEmerging treatments are being developed for inherited retinal diseases, requiring a clear understanding of natural progression and a database of potential participants for clinical trials. This article describes the rationale, study design and methodology of the Victorian Evolution of inherited retinal diseases NaTUral history REgistry (VENTURE), including data from the first 150 participants enrolled.MethodsVENTURE collects retrospective and prospective data from people with inherited retinal diseases. Following registration, participants are asked to attend a baseline examination using a standardised protocol to confirm their inherited retinal disease diagnosis. Examination procedures include (i) retinal function, using visual acuity and perimetry; (ii) retinal structure, using multimodal imaging and (iii) patient‐reported outcomes. Participants' molecular diagnoses are obtained from their clinical records or through targeted‐panel genetic testing by an independent laboratory. Phenotype and genotype data are used to enrol participants into disease‐specific longitudinal cohort sub‐studies.ResultsFrom 7 July 2020 to 30 December 2021, VENTURE enrolled 150 registrants (138 families) and most (63%) have a rod‐cone dystrophy phenotype. From 93 participants who have received a probable molecular diagnosis, the most common affected genes are RPGR (13% of all registrants), USH2A (10%), CYP4V2 (7%), ABCA4 (5%), and CHM (5%). Most participants have early to moderate vision impairment, with over half (55%) having visual acuities of better than 6/60 (20/200) at registration.ConclusionsThe VENTURE study will complement existing patient registries and help drive inherited retinal disease research in Australia, facilitating access to research opportunities for individuals with inherited retinal diseases.
Bio‐pharma in Iran: Escaping the middle‐income trap
Authors: Babaee Ali , Miremadi Iman , Mashayekhi Ali N. 
Published: May 2022

SummaryMotivationNeither state planning nor economic liberalization has allowed developing economies to escape from the middle‐income trap, owing mainly to institutional voids and hindering institutions. We need another explanation for development and the emergence of new institutions.PurposeHow have biopharmaceutical enterprises emerged in Iran, despite the obstacles faced? Can the collaborative agency of small groups of actors who know each other create new institutions and hence the conditions for biopharmaceutical firms to emerge? If so, who participates in such small groups, and how do they operate?Methods and approachWe interviewed 29 key participants and stakeholders in the Iranian bio‐pharma industry. We used grounded theory to identify key themes.FindingsBio‐pharma emerged owing to the efforts of a small group who successfully worked together to master the technology, to overcome institutional obstacles and widespread scepticism within Iran, and thereby to create new firms manufacturing biopharmaceuticals. The group succeeded because it was morally committed to creating the industry; it proceeded pragmatically, experimenting and learning; and leadership was shared and collective.Policy implicationsIn this case, we see the inverse of a top‐down process where government acts as principal and firms act as agents. Instead, strategic collaboration across government, university and firms, in a process of trial and error, has been able to make great progress to overcome obstacles to technical innovation that seem daunting for a middle‐income country.
Creating opportunities for patient participation in managing medications across transitions of care through formal and informal modes of communication
Authors: Ozavci Guncag , Bucknall Tracey , Woodward‐Kron Robyn , Hughes Carmel , Jorm Christine , Manias Elizabeth 
Published: May 2022

AbstractBackgroundCommunicating about medications across transitions of care is important in older patients who frequently move between health care settings. While there is increasing interest in understanding patient communication across transitions of care, little is known about older patients' involvement in formal and informal modes of communication regarding managing medications.ObjectiveThe aim of this paper was to explore how older patients participated in managing their medications across transitions of care through formal and informal modes of communication.MethodsThe study was conducted across two metropolitan hospitals: an acute hospital and a geriatric rehabilitation hospital in metropolitan Melbourne, Australia. A focused ethnographic design was used involving semi‐structured interviews (n = 50), observations (203 h) and individual interviews or focus groups (n = 25). Following thematic analysis, data were analysed using Fairclough's Critical Discourse Analysis.ResultsData analysis revealed two major discursive practices, which comprised of an interplay between formal and informal communication and environmental influences on formal and informal communication. Self‐created patient notes were used by older patients to initiate informal discussion with health professionals about medication decisions, which challenged traditional unequal power relations between health professionals and patients. Formal prompts on electronic medication administration records facilitated the continuous information discourse about patients' medications across transitions of care and encouraged health professionals to seek out older patients' preferences through informal bedside interactions. Environmental influences on communication comprised health professionals' physical movements across private and public spaces in the ward, their distance from older patients at the bedside and utilization of the computer systems during patient encounters.ConclusionOlder patients' self‐created medication notes enabled them to take on a more active role in formal and informal medication communication across transitions of care. Older patients and family members did not have continuous access to information about medication changes during their hospital stay and systems often failed to address older patients' key concerns about their medications, which hindered their active involvement in formal and informal communication.Patient or Public ContributionOlder adults, family members and health professionals volunteered to be interviewed and observed.
Identification of the cuticle protein AccCPR2 gene in Apis cerana cerana and its response to environmental stress
Authors: Tan Shuai , Li Guilin , Guo Hengjun , Li Han , Tian Ming , Liu Qingxin , Wang Ying , Xu Baohua , Guo Xingqi 
Published: May 2022

AbstractCuticular proteins (CPs) are known to play important roles in insect development and defence responses. The loss of CP genes can lead to changes in insect morphology and sensitivity to the external environment. In this study, we identified the AccCPR2 gene, which belongs to the CPR family (including the R&R consensus motif) of CPs, and explored its function in the response of Apis cerana cerana to adverse external stresses. Our results demonstrated that AccCPR2 was highly expressed in the late pupal stage and epidermis, and the expression of AccCPR2 may be induced or inhibited under different stressors. RNA interference experiments showed that knockdown of AccCPR2 reduced the activity of antioxidant enzymes, led to the accumulation of oxidative damage and suppressed the expression of several antioxidant genes. In addition, knockdown of AccCPR2 also reduced the pesticide resistance of A. cerana cerana. The overexpression of AccCPR2 in a prokaryotic system further confirmed its role in resistance to various stresses. In summary, AccCPR2 may play pivotal roles in the normal development and environmental stress response of A. cerana cerana. This study also enriched the theoretical knowledge of the resistance biology of bees.
Sintering and thermal expansion behaviors of glass and glass–YSZ composites as self‐repairable seals for SOFC
Authors: Rao Padmanapan , Singh Raj N. 
Published: May 2022

AbstractGlass and glass–ceramics are used as sealants in solid oxide fuel cell (SOFC) because their thermophysical properties can be tailored to meet the stringent requirements of the SOFC stack. The processing, sintering, and thermal expansion behaviors of self‐healing and non‐crystallizing glass and glass containing 10%–30 wt.% non‐reacting yttria‐stabilized zirconia (YSZ) are studied. The addition of inert YSZ to glass significantly retarded the sintering behavior. Thermal expansion behaviors of glass and glass–YSZ are also measured to study the role of YSZ addition on the glass transition, softening point, and coefficient of thermal expansion (CTE). It is shown that the densification is controlled by the viscous sintering mechanism, in which the addition of YSZ increased the effective viscosity of the glass–YSZ as evident from higher glass transition and softening temperatures and decreased CTE. These results demonstrated that the addition of YSZ to glass is promising for achieving optimum thermophysical properties useful as seals for SOFC.
Nanocarriers for combating biofilms: Advantages and challenges
Authors: Zhang Yuning , Lin Shiyu , Fu Jingyuan , Zhang Wei , Shu Gang , Lin Juchun , Li Haohuan , Xu Funeng , Tang Huaqiao , Peng Guangneng , Zhao Ling , Chen Shiqi , Fu Hualin 
Published: May 2022

AbstractBacterial biofilms are highly resistant to antibiotics and pose a great threat to human and animal health. The control and removal of bacterial biofilms have become an important topic in the field of bacterial infectious diseases. Nanocarriers show great anti-biofilm potential because of their small particle size and strong permeability. In this review, the advantages of nanocarriers for combating biofilms are analysed. Nanocarriers can act on all stages of bacterial biofilm formation and diffusion. They can improve the scavenging effect of biofilm by targeting biofilm, destroying extracellular polymeric substances and enhancing the biofilm permeability of antimicrobial substances. Nanocarriers can also improve the antibacterial ability of antimicrobial drugs against bacteria in biofilm by protecting the loaded drugs and controlling the release of antimicrobial substances. Additionally, we emphasize the challenges faced in using nanocarrier formulations and translating them from a preclinical level to a clinical setting.