bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of concentrated growth factor and blood clot as scaffolds in regenerative endodontic procedures: A retrospective study
Authors: Yang Fengjiao , Yu Lintong , Li Jiahui , Cheng Jing , Zhang Yishan , Zhao Xiaoe , Song Guangtai 
Published: July 2022

AbstractThe study aims to investigate and compare the success rate of concentrated growth factor (CGF) and blood clot (BC) as scaffolds in regenerative endodontic procedures (REPs). Immature permanent necrotic teeth treated by REPs with at least a 6‐month follow‐up were included. These teeth were divided into the CGF (53 teeth) and BC (68 teeth) groups. Treatment outcomes were assessed using a combined clinical and radiographic scoring system. The total success rate was 91.74% over a mean follow‐up period of 23.15 months. There was no significant difference between the CGF group (86.79%) and BC group (95.59%). The success rate of traumatic teeth (84.31%) was significantly lower than that of teeth with developmental dental anomalies (98.39%) (p < 0.05). CGF may be a suitable alternative scaffold in REPs when adequate bleeding cannot be achieved. Moreover, compared to developmental dental anomalies, traumatic teeth treated by REPs may be more vulnerable to failure.
Dissection videos as a virtual veterinary anatomy peer learning tool: Trialled at the University of Tehran during the Covid‐19 pandemic
Authors: Sadeghinezhad Javad 
Published: July 2022

AbstractThe Covid‐19 pandemic forced universities around the world to use online education instead of face‐to‐face teaching. Veterinary anatomy training was also affected, and laboratory classes were disrupted by this transition. To reduce the effects of virtual education on students' anatomy learning, peer learning using dissection videos was introduced at University of Tehran. This study describes the design and implementation of this method and evaluates the students' perceptions regarding this programme. The opinions of 98 students were examined using a questionnaire. The data showed that dissection videos were one of the main sources of anatomy study (67.3%). Among students who used videos, 69.6% students became more interested in anatomy and 73% learned anatomy better with this approach. Students used these videos to review anatomy (88.7%) and even learn new content (87.6%). Most surveyed students used laptops (73%) and cell phones (14.6%) to watch videos. In this study, 19.1% of respondents were estimated to be low users, 68.5% medium users and 12.4% high users. A large number of students (83.1%) trusted their peer teacher in providing the lesson. Dissection videos play an important role in conveying a three‐dimensional understanding of anatomical structures, and peer teaching is also effective in learning because of the strong connection between tutors and tutees. This study supports students' acceptance of the use of peer dissection videos for learning online veterinary anatomy.
Three cases of symmetrical drug‐related intertriginous and flexural exanthema (SDRIFE) induced by proton‐pump inhibitors
Authors: Spigariolo Cristina B. , Barei Francesca , Maronese Carlo A. , Barberi Francesco , Cattaneo Angelo , Violetti Silvia Alberti 
Published: July 2022

AbstractSymmetrical drug‐related intertriginous and flexural exanthema (SDRIFE), previously termed drug‐related baboon syndrome, is an uncommon drug eruption. It is characterized by symmetrical erythema involving the gluteal and/or inguinal area in association with one other intertriginous area in the absence of systemic involvement. It typically develops a few hours to days after drug exposure. The diagnosis is based on clinical presentation and drug history. The treatment consists mainly of withdrawal of the causative agent; corticosteroids (topical or systemic) are prescribed to accelerate the resolution. We present three cases that appeared after proton‐pump inhibitors (PPIs) intake.
Review of dermatologic medications and impact on male fertility, sexual dysfunction and teratogenicity
Authors: Hui Edward XW , Huang Xiaoling , Oon Hazel H. 
Published: July 2022

AbstractBackgroundDermatologic medications have been linked to issues with safety during pregnancy and lactation. Despite this, limited research, often with conflicting findings, has been published on the association between dermatologic medications, male infertility, sexual dysfunction and teratogenicity following paternal exposure.ObjectiveThis review seeks to provide evidence‐based guidance for physicians who are prescribing dermatologic medications to male patients who are trying to conceive.MethodsCommon medications used in the largest outpatient specialist dermatologic centre in Singapore were the focus of this review. A PubMed search using MeSH terms from inception to April 22, 2021, was conducted. A secondary search was conducted to include common non‐dermatologic medications. Drug information from various online clinical resources and the Tenth Edition of Drugs in Pregnancy and Lactation was also used as a reference.ResultsIn this review of 234 studies, 131 medications were covered. A total of 34 medications were associated with male infertility and sexual dysfunction, while 16 medications were implicated with concerns of teratogenicity.Discussion and conclusionPhysicians are advised to discuss the potential impact on male fertility and teratogenicity with males who are trying to conceive while taking into consideration the clinical efficacy and tolerability of these medications and alternative treatments.
TRIM26 inhibits hepatitis B virus replication by promoting HBx degradation and TRIM26 genetic polymorphism predicts PegIFNα treatment response of HBeAg‐positive chronic hepatitis B Patients
Authors: Luo Mengqi , Hou Jia , Mai Haoming , Chen Jiaxuan , Chen Haitao , Zhou Bin , Hou Jinlin , Jiang De‐Ke 
Published: July 2022

SummaryBackgroundHepatitis B virus (HBV) infection is a serious global health burden. TRIM26 has been reported to affect hepatitis C virus replication.AimsTo manifest the role of TRIM26 on HBV replication and explore if there are single‐nucleotide polymorphisms (SNPs) in TRIM26 associated with response to pegylated interferon‐alpha (PegIFNα) treatment in patients with chronic hepatitis B (CHB).MethodsWe investigated the effect and mechanism of TRIM26 on HBV replication in vitro. The association between SNPs in TRIM26 and PegIFNα treatment response was evaluated in two independent cohorts including 238 and 707 patients with HBeAg‐positive CHB.ResultsKnockdown of TRIM26 increased, while overexpression of TRIM26 inhibited, HBV replication. Co‐immunoprecipitation assays and immunofluorescence showed that TRIM26 interacted and co‐localised with HBx. Co‐transfection of HBx‐HIS and TRIM26‐FLAG plasmids in Huh7 cells showed that TRIM26 inhibited the expression of HBx. Furthermore, TRIM26 inhibited HBV replication by mediating HBx ubiquitination degradation, and TRIM26 SPRY domain was responsible for the interaction and degradation of HBx. Besides, IFN increased TRIM26 expression. TRIM26 rs116806878 was associated with response to PegIFNα in two CHB cohorts. Moreover, a polygenic score integrating TRIM26 rs116806878, STAT4 rs7574865 and CFB rs12614 (previously reported to be associated with response to PegIFNα) was related to response to PegIFNα in CHB.ConclusionsTRIM26 inhibits HBV replication; IFN promotes TRIM26 expression. TRIM26 exerts an inhibitory effect on HBx by promoting ubiquitin‐mediated degradation of HBx. Furthermore, TRIM26 rs116806878 is a potential predictive biomarker of response to PegIFNα in patients with CHB.
Menopause, skin and common dermatoses. Part 4: oral disorders
Authors: Ashraf Mariha , Kamp Erin , Musbahi Esra , DeGiovanni Claudia 
Published: July 2022

Abstract
The physiological impact of declining oestrogen levels during menopause has been well documented. We conducted a literature review to assess the impact of menopause on oral health. Falling oestrogen levels are associated with adverse effects on the gingival, oral and buccal epithelia. The symptoms prevalent in perimenopausal and postmenopausal women range from dry mouth to immune-mediated mucocutaneous disease and burning mouth syndrome. Our review has highlighted the need for further research into potential treatments for oral symptoms in menopause, particularly with regard to hormone replacement therapy.
A qualitative study exploring the perceptions of health among pre‐teen girls from disadvantaged communities in Dublin
Authors: Dow Mckenzie , Murrin Celine , O'Malley Grace , Brinkley Aoife , Bel‐Serrat Silvia 
Published: July 2022

AbstractThere are disparities in health outcomes between youth from higher and lower socioeconomic backgrounds, and girls are especially vulnerable to changes in health‐related behaviours as they develop. Therefore, this study explored how girls from disadvantaged communities in Dublin, Ireland, make sense of ‘being healthy.’ A phenomenological qualitative design was implemented. Three focus groups were conducted (n = 22, 10–12 years) and data were analysed using thematic analysis. Food and physical appearance featured prominently within the girls' definitions of health. Girls and their families from low‐SES backgrounds may experience more difficulties with time scarcity as well as environmental barriers to a healthy lifestyle.
A new method for determination of the relative colour strength of dye based on new colour depth formula. Part II: application to different batches of colourant
Authors: Xie Wanzi , Wang Hongbo , Yang Hongying , Zhang Jingjing , Qi Mengyuan 
Published: July 2022

AbstractAs a standard for the evaluation of relative colour strength (RCS) of dye, AATCC EP‐6 (SWL [K/S], SUM, and WSUM) has been widely used, while its limitations are often overlooked by people. In Part I of this study, the new method Yangn (CSV1, CSV2, and CSV3) for the determination of RCS were proposed, Yangn and AATCC EP‐6 were tested using the different types of disperse dyes that have approximate hues. However, the calculations of RCS for the same dyes produced in different batches were also necessary, therefore, this article (Part II) focuses on it. The HL series dyes produced in 2020 and 2021 were used to test Yangn and AATCC EP‐6. The same results as Part I, the colour strength values calculated by SWL, SUM, and WSUM were inconsistent. Furthermore, in the methods of AATCC EP‐6, the colour strength values calculated by WSUM should be at least rounded to four decimal places to avoid false calculation; the value of Yangn only need to be rounded to two decimal places. For the RCS of the same dyes produced in different batches, the methods of AATCC EP‐6 and Yangn were relatively the same under different dyeing concentrations. The coefficient of variation (CV) values of Yangn were < 1.3%, the CV values of AATCC EP‐6 were < 2%. Therefore, according to the consistency of the calculation, the CV values and the dependence on the concentration, the new methods of Yangn were superior to the traditional methods.
Risk factors for increased length of hospital stay among young pediatric patients who suffer facial fractures
Authors: Stanbouly Dani , Kocaelli Humeyra , Arce Kevin , Selvi Firat 
Published: July 2022

AbstractBackground/AimIt is not known whether the mechanism of facial trauma influences the associated length of hospitalization. The aim of this study was to determine whether the mechanism of injury influenced the length of hospital stay (LOS) among pediatric patients who sustained facial fractures.Materials and methodsThis retrospective cohort study was completed using the Kids' Inpatient Database (KID). The primary predictor variable was the mechanism of injury. The primary outcome variable was LOS. Linear regression was used to determine independent predictors of increased/decreased length of stay. A p‐value of less than .05 was considered statistically significant.ResultsThe final sample consisted of 2865 subjects aged 12 years or younger who had suffered facial fractures. The most common mechanism of injury was motor vehicle accidents (MVA) (58.6%). Facial fractures due to MVA added 1.20 days (95% CI, 0.02, 2.38; p < .05) when compared to those due to a fall.ConclusionsMVA significantly prolonged the LOS among young pediatric patients who sustained facial fractures, reflecting the exceptional amount of force involved. Having a chronic condition was also a significant factor for longer LOS. Four or more fractures also led to a longer LOS.
Landscape woody features, local management and vegetation composition shape moth communities in extensively managed grasslands
Authors: Kühne Isabel , Arlettaz Raphaël , Humbert Jean‐Yves 
Published: July 2022

Abstract
Agricultural intensification has led to a dramatic impoverishment of biodiversity. Moths are not an exception: rapid declines of common and widespread species have been reported and it is still not clear which conservation measures should be applied to restore their populations.
We investigated how much of the variation in moth assemblages inhabiting extensively managed meadows in a region of high‐intensity agriculture is explained by surrounding woody landscape features, meadow management and vegetation composition, and which specific variables are the most influential.
Results show that the percentage of forest and the length of hedgerows within a 250 m radius were especially important for forest macromoths, explaining 42% of variation in abundance and 23% of species richness, whereas meadow management played a relatively marginal role. The abundance of grassland macromoths was also positively influenced by the length of hedgerows in the landscape (combined with elevation it explained 10% of the variance), while it responded negatively to uncut refuge and to delayed mowing (7%). Regarding grassland macromoth species richness, the annual harvesting frequency was the main predictor (4%). In contrast, micromoth abundance was more influenced by meadow management, notably the date of the first cut (4%) and vegetation composition (8%, though not conclusive due to a single outlier), whereas landscape features explained nothing.
Altogether, these results demonstrate the importance of both woody features within farmed landscapes and biodiversity‐friendly meadow management for the maintenance of integral moth communities.
Cultural influences on future transportation technology usage: The role of personal innovativeness, technology anxiety and desire
Authors: Kwarteng Michael Adu , Ntsiful Alex , Osakwe Christian Nedu , Jibril Abdul Bashiru , Chovancova Miloslava 
Published: July 2022

AbstractThis study develops and validates a model, based on personal cultural values theory and psychological research, in relation to technology adoption. The model focuses specifically on the future use of on‐demand air mobility (ODAM), which is expected to have significant implications for city commuting and personal well‐being in the years ahead. We use a path modelling approach, in addition to recently advanced analytical methods such as the finite mixture partial least squares (FIMIX‐PLS), measurement invariance of composite models (MICOM) and multi‐group analysis, to validate the model using a data set of 627 young consumers from the Czech Republic. The research model explains 45.2% variation in the future use of ODAM using our global model. This variance explained in the future use of ODAM increases to 62.3% and 64.5% respectively, when we segment our data set into two groups. The results also show that tradition has significant influence on technology anxiety, personal innovativeness and desire to use ODAM. Independence positively affects personal innovativeness but not the desire to use ODAM. We also find that technology anxiety influences the desire to use, which in turn influences the future use of ODAM. However, we find group differences in the influence of ambiguity intolerance on technology anxiety, desire and personal innovativeness. Thus, the study also evaluates the existence of significant differences between two groups in our data set. Overall, the study suggests that individual cultural values play a particularly important role in influencing the future use of ODAM through psychological characteristics. The research implications of the study are discussed in the article.
Deep learning‐based classification of dermatological lesions given a limited amount of labelled data
Authors: Krammer S. , Li Y. , Jakob N. , Boehm A.S. , Wolff H. , Tang P. , Lasser T. , French L.E. , Hartmann D. 
Published: July 2022

AbstractBackgroundArtificial intelligence (AI) techniques are promising in early diagnosis of skin diseases. However, a precondition for their success is the access to large‐scaled annotated data. Until now, obtaining this data has only been feasible with very high personnel and financial resources.ObjectivesThe aim of this study was to overcome the obstacle caused by the scarcity of labelled data.MethodsTo simulate the scenario of label shortage, we discarded a proportion of labels of the training set. The training set consisted of both labelled and unlabelled images. We then leveraged a self‐supervised learning technique to pretrain the AI model on the unlabelled images. Next, we fine‐tuned the pretrained model on the labelled images.ResultsWhen the images in the training dataset were fully labelled, the self‐supervised pretrained model achieved 95.7% of accuracy, 91.7% of precision and 90.7% of sensitivity. When only 10% of the data were labelled, the model could still yield 87.7% of accuracy, 81.7% of precision and 68.6% of sensitivity. In addition, we also empirically verified that the AI model and dermatologists are consistent in visually inspecting the skin images.ConclusionsThe experimental results demonstrate the great potential of the self‐supervised learning in alleviating the scarcity of annotated data.
Single and combined 1064 nm Q‐switched Nd: YAG laser therapy in melasma: A meta‐analysis
Authors: Zhang Beilei , Xie Bo , Shen Yuqing , Zhang Li , Song Xiuzu 
Published: July 2022

AbstractPurposeThis article attempted to describe the efficacy and safety of 1064QNYL in combination with other treatments for refractory melasma.MethodsTwo researchers independently retrieved randomized controlled trials (RCTs) according to inclusion and exclusion criteria. Primary outcome was evaluated with MASI and mMASI scores in control group and experiment group. The secondary outcome was evaluated with MI scores. We calculated 95% CI of standardized mean difference (SMD) and heterogeneity of the included literature by Higgins I2 test, and assessed publication bias by Funnel plots, Egger's, and Begg's tests.ResultsA total of 12 articles including 322 subjects were analyzed. Experiment group was treated with 1064QNYL combined with single treatment (e.g., PDL, IPL, RF, and TA). Control group was treated with 1064QNYL alone. A greater reduction of Melasma Area and Severity Index (MASI)/modified Melasma Area and Severity Index (mMASI) scores were shown in experiment group than that in control group at the end of the treatment (SMD, −0.37; 95% CI −0.70 to −0.04, p = 0.03, I2 = 33%). The SMD of MI scores further supported this conclusion by −0.32 (95% CI −0.63 to −0.02, p = 0.04, I2 = 27%). As for adverse events (AEs), combined treatment gave rise to more mild burning, stinging, and erythema that resolved spontaneously. Several studies reported focal purpura, punctate leukoderma, hyperpigmentation, hypopigmentation, and so on.ConclusionCombined 1064QNYL treatment was better than single laser treatment, with the highest short‐term benefit and long‐term follow‐up to maintain the effect in favor of combined treatment.
The Benefits of School Recess: A Systematic Review *
Authors: Hodges Virginia C. , Centeio Erin E. , Morgan Charles F. 
Published: July 2022

ABSTRACTBACKGROUNDRecess provides many physical, mental, and social benefits for students; however, the most recent systematic review examining the benefits of recess was conducted over a decade ago. The purpose of this paper was to determine the current benefits of school recess by conducting an updated systematic review of the literature.METHODSMultiple databases were systematically examined to find articles fitting the following inclusionary criteria: (a) school recess, (b) all schooling before college, and (c) recess benefits of any kind. Research was limited to literature published between June 2009 and July 2020.RESULTSNine studies were included in this review. The majority of studies examined elementary‐aged students. Seven studies were conducted in the United States, and 2 studies were conducted internationally. Recess provided school‐aged children academic and cognitive benefits, behavioral and emotional benefits, physical benefits, and social benefits.IMPLICATIONS FOR SCHOOL HEALTH POLICY, PRACTICE, AND EQUITYProviding recess for all school levels positively impacts the whole child; there was no literature implicating negative impacts of recess.CONCLUSIONSSchools can improve overall student health and belonging by redesigning and/or implementing daily recess.
Textural analyses and artificial neural network as optimization tools to predict the sensory perception of cosmetic emulsions
Authors: Franzol Angélica , Banin Thais Mancini , Brazil Tayra Rodrigues , Rezende Mirabel Cerqueira 
Published: July 2022

AbstractThis study shows a methodology which correlates sensory perception and predictive simulations performed in a model based on artificial neural network (ANN), inputted with textural data. The study used 39 sunscreen samples available in Asia, North America, Latin America, and Europe. Experimental textural analyses considered spreadability, back extrusion, and tackiness and the results were inputted in the ANN model. Sensory tests with 325 panelists distributed in the four mentioned regions (approximately 80 panelist per region) were carried out and 14 attributes were evaluated. The correlation between the predictive simulations and sensory tests showed precision of 60–84% for the majority of attributes. Few attributes showed correlation in the range of 37–60%. This study shows as a practical application a model to estimate consumer acceptance of sunscreen products using ANN and experimental textural results. This tool proved to be reliable, being a competitive advantage in the development of new cosmetic emulsions.Practical applicationsThe assessment of textural and sensory characteristics of cosmetic products is critical for their development and further acceptance by consumers. Ideally, the most accurate evaluation is the experimentation in use by screened consumers (panelists), but this test is equally time‐consuming and expensive. In this scenario, this work presents as a practical application a tool to predict consumer acceptance of cosmetic emulsions based on an artificial neural network model inputted with textural data.