bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thirty-Year Time Trends in Diabetic Retinopathy and Macular Edema in Youth With Type 1 Diabetes
Authors: Allen Digby W. , Liew Gerald , Cho Yoon Hi , Pryke Alison , Cusumano Janine , Hing Stephen , Chan Albert K. , Craig Maria E. , Donaghue Kim C. 
Published: May 2022

OBJECTIVE
To examine trends in diabetic retinopathy (DR) and diabetic macular edema (DME) in adolescents with type 1 diabetes between 1990 and 2019.

RESEARCH DESIGN AND METHODS
We analyzed 5,487 complication assessments for 2,404 adolescents (52.7% female, aged 12–20 years, diabetes duration &gt;5 years), stratified by three decades (1990–1999, 2000–2009, 2010–2019). DR and DME were graded according to the modified Airlie House classification from seven-field stereoscopic fundal photography.

RESULTS
Over three decades, the prevalence of DR was 40, 21, and 20% (P &lt; 0.001) and DME 1.4, 0.5, and 0.9% (P = 0.13), respectively, for 1990–1999, 2000–2009, and 2010–2019. Continuous subcutaneous insulin infusion (CSII) use increased (0, 12, and 55%; P &lt; 0.001); mean HbA1c was bimodal (8.7, 8.5, and 8.7%; P &lt; 0.001), and the proportion of adolescents meeting target HbA1c &lt;7% did not change significantly (8.3, 7.7, and 7.1%; P = 0.63). In multivariable generalized estimating equation analysis, DR was associated with 1–2 daily injections (odds ratio 1.88, 95% CI 1.42–2.48) and multiple injections in comparison with CSII (1.38, 1.09–1.74); older age (1.11, 1.07–1.15), higher HbA1c (1.19, 1.05–1.15), longer diabetes duration (1.15, 1.12–1.18), overweight/obesity (1.27, 1.08–1.49) and higher diastolic blood pressure SDS (1.11, 1.01–1.21). DME was associated with 1–2 daily injections (3.26, 1.72–6.19), longer diabetes duration (1.26, 1.12–1.41), higher diastolic blood pressure SDS (1.66, 1.22–2.27), higher HbA1c (1.28, 1.03–1.59), and elevated cholesterol (3.78, 1.84–7.76).

CONCLUSIONS
One in five adolescents with type 1 diabetes had DR in the last decade. These findings support contemporary guidelines for lower glycemic targets, increasing CSII use, and targeting modifiable risk factors including blood pressure, cholesterol, and overweight/obesity.
Color Changes Associated with Sandblasting, Hydrofluoric Acid Etching, and Er:YAG Laser Irradiation of Milled Feldspathic Porcelain Laminate Veneers
Authors: Al-Wahadni AM , Abu Al-Addous AM , Nattress BR , Jum’ah A 
Published: May 2022

SUMMARY

Objectives
To evaluate color changes in milled feldspathic porcelain laminate veneers following hydrofluoric acid etching (HFA), sandblasting (SB), or Er:YAG laser irradiation (LI).

Methods and Materials
Disc-shaped specimens (thickness=1 mm, diameter=8 mm) were milled from feldspathic porcelain blocks (n=40). Glazed specimens were randomly assigned to four subgroups (n=10 each) according to surface treatment: negative control, HFA, SB, and LI. A layer of translucent, light-cured resin cement (thickness=0.1 mm) was then applied following silanization. The color was characterized by the L*, a*, and b* uniform color space (CIE) using a reflection spectrophotometer. CIEDE2000 (ΔE00) was calculated to determine the color difference between each surface treatment and negative control groups. Data were statistically analyzed using analysis of variance (ANOVA), Kruskal-Wallis, and Dunn-Bonferroni post hoc tests.

Results
There were no significant differences in CIEL* and CIEb* coordinates between negative control and all surface treatment groups (p≥0.108). The SB group demonstrated significantly lower mean CIEa* (higher greenish hue) compared to other groups (p≤0.003). HFA exhibited significantly higher CIEa* (closer to red) when compared to LI (p=0.039). LI induced the smallest overall color change compared to negative control (ΔE00=1.43 [1.07]). However, the differences in ΔE00 values were not statistically significant (p=0.648).

Conclusions
The tested surface treatments did not affect the lightness or the yellowness of the 1-mm-thick milled feldspathic porcelain veneers. However, sandblasting resulted in a significant increase in the greenish hue. The Er:YAG laser resulted in the closest ΔE00 (1.43) to the 50:50% perceptibility threshold (ΔE00=1.2).
Perancangan Aplikasi Bercocok Tanam Pada Kawasan Perkotaan Berbasis Android
Authors: Pratama Naufal Alip , Putri Devi Afriyantari Puspa 
Published: May 2022

Kawasan perkotaan yang merupakan pusat ekonomi mendorong orang-orang untuk beraktiftas dan bekerja disana. Hal itu sejalan dengan pertumbuhan bangunan mulai dari perkantoran, industri, serta tempat tinggal yang semakin padat. Dengan semakin sedikitnya ruang terbuka pada kawasan perkotaan membuat kesadaran masyarakat dalam berkebun dan bercocok tanam semakin berkurang. Metode urban agriculture dibutuhkan dalam sistem pertanian perkotaan, dengan metode ini produksi tanaman dapat dilakukan dengan efisien dalam lahan yang terbatas. Penelitian ini dilakukan untuk merancang aplikasi yang bertujuan memberi panduan dan diskusi antar pengguna dalam melakukan urban agriculture untuk mengatasi keterbatasan lahan dalam bercocok tanam pada kawasan perkotaan. Aplikasi dibuat dengan basis android menggunkan sdk flutter dan Firebase dalam menyimpan basis data. Dalam penelitian ini penulis menggunakan metode System Development Life Cycle (SDLC) dengan pendekatan menggunakan model Waterfall. Penelitian menghasilkan aplikasi android yang bernama “PlantGo” yang bisa digunakan oleh masyarakat umum. Pengujian aplikasi menunjukan hasil yang bagus, yang dimana dalam pengujian Black Box seluruh fitur berjalan dengan semestinya dan pengujian Usability dengan 30 responden menghasilkan hasil yang bagus dengan skor 89,75% yang dimana aplikasi tersebut dapat diterima dengan baik oleh pengguna.
KECEMASAN TERHADAP MATA AJAR ILMU PENGETAHUAN ALAM (IPA) PADA SISWA SEKOLAH DASAR DAN MENENGAH
Authors: Parikesit Arli Aditya 
Published: May 2022

Ilmu Pengetahuan Alam (IPA) merupakan mata ajar wajib yang diajarkan di sekolah dasar dan menegah. Permasalahan yang terjadi pada pembelajaran IPA adalah terjadinya kecemasan pada siswa. Kecemasan pada IPA terjadi di berbagai spektrum populasi siswa, mulai dari kelompok minoritas, sampai pada kebangsaan dan gender tertentu. Di Indonesia, kecemasan IPA juga telah terjadi, dan menjadi masalah serius. Saat ini beberapa solusi untuk mengatasi kecemasan IPA sudah dapat dilakukan, diantaranya melalui pembelajaran tematik, pengembangan sekolah anak berbakat, pendekatan psikoterapi, pendekatan spiritualisme, kondisi kelas yang positif, Problem Based Learning, dan teknologi informasi. Namun, keberhasilan semua pendekatan tersebut baru dapat terjamin jika guru dapat menjalankan peran sebagai motivator bagi siswa.
Peningkatan Kemampuan Pemecahan Masalah Dan Disposisi Matematis Siswa SMK Dengan Pembelajaran Berbasis Masalah Berbantuan Multimedia Interactive
Authors: Asmara Andes Safarandes 
Published: May 2022

Masalah pokok yang dianalisis dalam penelitian ini adalah: untuk mengetahui peningkatan kemampuan pemecahan masalah dan disposisi matematis siswa SMK sebagai dampak dari penggunaan pembelajaran berbasis masalah berbantuan multimedia interactive (geogebra). Metode penelitian adalah mixed methods sequential explanatory. Penelitian ini merupakan studi eksperimen yang melibatkan siswa kelas XI sebanyak dua kelas dengan sampel 43 siswa jurusan Analisis Kimia, instrumen yang digunakan ini adalah tes kemampuan pemecahan masalah, skala disposisi matematis siswa, observasi serta wawancara, data dianalisis secara deskriftif dan di uji statistik menggunakan uji normalitas, uji Mann Whitney, analisis korelasi-t. Berdasarkan hasil data analisis disimpulkan bahwa peningkatan kemampuan pemecahan masalah dan disposisi matematis siswa dengan pembelajaran berbasis masalah berbantuan multimedia interactive lebih baik dari pada kemampuan pemecahan masalah dan disposisi matematis siswa yang mendapat pembelajaran secara konvensional.
Technology Acceptance Models pada Teknologi Digital: Survey Paper
Authors: Nofita Megia , Sebastian Danny 
Published: May 2022

Pertumbuhan teknologi yang pesat membawa dampak yang besar bagi masyarakat dan membawa masyarakat untuk mampu beradaptasi dengan terbukanya informasi. Banyak bidang mengintegrasikan teknologi dalam pekerjaannya. Akan tetapi, persoalan adaptasi akan menjadi persoalan yang besar bagi masyarakat di saat teknologi baru bermunculan. Untuk mengevaluasi dan memprediksi perilaku masyarakat dibutuhkan kerangka kerja yaitu TAM (Teori Acceptance Model) di mana model ini populer dan banyak digunakan dalam studi perilaku saat menggunakan teknologi. Penelitian ini bertujuan untuk 1) melihat TAM dari sudut pandang kerangka kerja dan perluasan TAM, 2) tujuan menggunakan TAM, 3) variabel eksternal yang digunakan selain konstruksi TAM, 4) identifikasi bidang apa saja yang menggunakan TAM pada teknologi digital dalam tahun 2021 dengan menggunakan SLR (Systematic Literature Review), serta 5) mengidentifikasi pada topik penelitian dan menjawab pertanyaan penelitian dan didapatkan selama tahun 2021. Kerangka kerja TAM dengan dua konstruksi utama PEUO dan PU masih bersifat adaptif dan kontekstual dalam berbagai bidang. Contohnya pendidikan, bisnis, akomodasi, pariwisata, dan perbankan dengan tujuan menguji, mengidentifikasi, menyelidiki, dan menguji akuntabilitas faktor-faktor yang mempengaruhi perilaku dengan beberapa variabel tambahan.
Flood Frequency Analysis and Hydraulic Design of Bridge at Mashan on River Kunhar
Authors: Riaz Khuram , Aslam Hafiz Muhammad Shahzad , Yaseen Muhammad Waseem , Ahmad Hafiz Haseeb , Khoshkonesh Alireza , Noshin Sadaf 
Published: May 2022

Abstract
Kunhar River hydrology and hydraulic design of a bridge on this river are being studied using HEC-Geo-RAS and Hydrologic Engineering Centers River Analysis System (HEC-RAS). The river flows in the northern part of Pakistan and is 170 km long. On both sides of the river, there are residential settlements. The river hydraulics is studied by using 30-metre remotely sensed shuttle radar topographic mission - digital elevation model (SRTM DEM) and Arc Map. 32 cross-sections are imported from Geographic Information System (GIS) to HEC-RAS. On historical peak flow results, the extreme value frequency distribution is applied, and a flood is determined for a 100-year return period, with a discharge estimated as 2223 cubic metres. Three steady flow profiles are adopted for HEC-RAS, the first is for the maximum historical peak data, the second is for the 100-year return period, and the third profile is for the latter 100-year period with a safety factor of 1.28. With remote sensing-based assessments, the proposed location for a bridge is determined and then verified with a field survey which was physically conducted. The maximum water height estimated in the river is about 4.26 m. This bridge will facilitate about 50 thousand population of Masahan and its surroundings. It will create a shortest link between Khyber Pakhtunkhwa and Azad Kashmir and thus will enhance tourism and trade activities.
Från mål till röd tråd
Authors: Waaranperä Ulrika Kolben 
Published: May 2022

Lärandemålen är centrala för hur kurser utformas, planeras, genomförs och bedöms. Ändå är min erfarenhet att jag sällan lyckas integrera lärandemålen i undervisningen på ett konkret sätt under kursens gång. I artikeln diskuterar jag hur lärandemålen kan arbetas in i lärande- och undervisningsformerna, och därmed bli en del av undervisningens och lärandeprocessens röda tråd. Jag presenterar tre möjliga arbetsformer för att förstärka studenternas reflektion kring lärandemålen. Ett av dessa exempel – det modifierade minut-pappret – har jag använt mig av i praktiken. Även om mitt försök att omvandla lärandemålen från döda formuleringar i ett kursdokument till att bli mer av lärandeprocessens röda tråd var både begränsat och utfört utan någon större systematik, är min slutsats att detta bidrog till en mer öppen akademisk miljö. Detta är möjligen ett steg i riktning mot den sociala kontextualieringsprocessen, genom vilken studenten införlivar den syn på vetenskapligt utforskande av världen som akademisk utbildning ytterst ska uppmuntra. Men för att nå hela vägen är arbetsformerna under en enskild kurs långt ifrån tillräckliga.
Online Media Platforms' influence on student perception of Blended Learning
Authors: Eriksson Anna , Alégroth Emil , Nygren Åse 
Published: May 2022

Abstract: Blended learning, definierat som kombinationen av multipla läroformer i en gemensam utbildningskontext, har kallats "den nya normen" inom högre utbildning. I modern blended learning så innebär "blending" ofta en blandning av traditionell utbildning i klassrum kombinerat med digital undervisning för att möjliggöra distansundervisning. Parallellt med detta skifte inom undervisningen så har sociala normer kring hur vi tar till oss information för självständigt lärande och avslappning ändrats mot användningen av mer internetbaserade plattformar så som YouTube och streamad video.
Forskningsproblem: I denna studie undersöker vi om detta skifte i sociala normer har en koppling till studenters syn på blended learning i sub-fältet mjukvarutestning inom Software Engineering.
Metodik: Studien genomfördes med studenter på mastersnivå i en kurs inom mjukvarutestning (Software Testing, PA2552) under våren 2020 på Blekinge Tekniska Högskola (BTH). Data samlades in genom en online enkät bestående av 78 frågor som besvarades av 19 studenter.
Resultat: Resultaten visar att tidigare studenterfarenhet med blended learning, motivation till lärande och användning av online plattformar för självständigt lärande och avslappning har varierande påverkan på studenternas upplevelser och syn på värdet av blended learning. Detta resultat ger värdefulle insikter för beslutsfattande om blended learning, speciellt för studentgrupper med mer konservativ syn till digitalt lärande, vilket kan begränsa användandet av internetbaserade teknologi på grund av kulturella skäl.
KAJIAN FAKTOR INTRINSIK DAN KEMAMPUAN LITERASI SAINS SISWA SMP DI KOTA BANDAR LAMPUNG
Authors: Maulina Dina , Widyastuti  , Maulina H. , Mayasari S. 
Published: May 2022

Kajian Faktor Intrinsik dan Kemampuan Literasi Sains Siswa SMP di Kota Bandar Lampung. Penelitian ini bertujuan untuk mendeskripsikan faktor penguatan intrinsik dan keberhasilan pelaksanaan literasi sains pada jenjang SMP di kota Bandar Lampung saat pemberlakuan pembelajaran daring selama Pandemi Covid-19. Sampel penelitian sebanyak 331 siswa SMP yang berasal dari kelas VIII tahun ajaran 2020/2021. Sampel dipilih melalui kombinasi teknik stratified dan cluster random sampling untuk memperoleh jumlah sampel yang representatif. Perolehan data penelitian dilakukan dengan menggunakan instrumen beruapa tes literasi sains dan kuesioner penguatan intrinsik. Representasi data selanjutnya dianalisis secara deskriptif melalui nilai presentase. Hasil penelitian menunjukkan bahwa (i) faktor intrisik pada seluruh indikator masih di bawah 25%, (ii) indikator minat siswa dari dalam diri siswa dalam pelaksanaan pembelajaran sains selama belajar daring dalam kategori tinggi (18,7%) dan (iii) siswa menyadari ketergunaan untuk melakukan belajar sains dalam kategori tinggi (20,5%) dan (iv) kemampuan literasi sains siswa berdasarkan kompetensinya masih tergolong rendah, dengan keseluruhan aspek literasi sains menunjukan nilai kurang dari 16%.
Kata kunci: faktor intrinsik, literasi sains, pembelajaran daring, sekolah menengah pertama.

ABSTRACT
Study of Intrinsic Factors and Science Literacy Ability of Junior High School Students in Bandar Lampung. This study aims to describe the intrinsic reinforcement factor and the success of implementing scientific literacy at the junior high school level in Bandar Lampung during the implementation of online learning in Covid-19 pandemic. The research sample was 331 of 8th grade junior high school students in academic year 2020/2021. Samples were selected through a combination of stratified techniques and cluster random sampling to obtain a representative sample. The data was obtained through scientific literacy test and an intrinsic reinforcement questionnaire. The data analyzed descriptively through the percentage value. The results reveals the fact that: (i) the intrinsic factor in all indicators lower than 25%; (ii) the indicator of students’ interest in the implementation of science learning during online learning was in the high category (18.7%); (iii) students awareness of the usefulness of learning science in the high category (20.5%); and (iv) students’ scientific literacy ability is relatively low (the overall scientific literacy aspect less than 16%).
Keywords: intrinsic factor, scientific literacy, online learning, junior high school.
A case of cribriform plate dural arteriovenous fistulas with a rare complication after endovascular therapy
Authors: Takano Issei , Takigawa Tomoji , Shimmyo Kei , Anazawa Toru , Kanaya Takahiro , Fujii Yoshiko , Nariai Yasuhiko , Sugiura Yoshiki , Suzuki Ryotaro , Nagaishi Masaya , Hyodo Akio , Suzuki Kensuke 
Published: May 2022

Background:
Cribriform plate dural arteriovenous fistulas (dAVFs) are rarely encountered. Here, we report a case of cribriform plate dAVF with a rare complication after endovascular therapy.

Case Description:
A 60-year-old man presented with severe sudden headache. Head computed tomography showed right subdural hematoma, and magnetic resonance angiography showed dilated bilateral frontal cortical vein. Digital subtraction angiography revealed cribriform plate dAVF fed by the anterior and posterior ethmoidal branches of the bilateral ophthalmic arteries. Transarterial embolization with liquid embolic material was performed and the fistula disappeared. Although magnetic resonance imaging showed the disappearance of the cribriform plate dAVF and subdural hematoma, the patient complained of anosmia after the procedure.

Conclusion:
Endovascular embolization is an effective treatment option for treating cribriform plate dAVFs. However, anosmia is a possible complication, and endovascular surgeons should take care of this complication, especially in cribriform plate dAVFs supplied with blood bilaterally.
Co-immunolocalization of Disc1 and Gas7 protein in adult mice brain
Authors: Kumar Udaya 
Published: May 2022

Objective: The aim of the present study was to check the potential interaction of two neurodevelopmental proteins, Disc1 and Gas7, in the adult mice brain. Methods: Twenty-four male Swiss albino mice were used for the study. The mice were 12 weeks old in the beginning of the experiment. Immunohistochemistry and co-immunofluorescence were performed on the coronal sections of mice brain and immunoblotting and co-immunoprecipitation were done on the whole brain lysate. Results: Data from immunohistochemistry and co-immunofluorescence indicate the occurrence and co-localization of Disc1 and Gas7 proteins in soma and projections of the brain cells. Immunostaining was observed in cerebral cortex, hypothalamus, midbrain, pons, medulla oblongata and CA3 of hippocampus of the brain. The data from Immunoblotting and co-immunoprecipitation validates the presence and interaction of Disc1 and Gas7 protein in whole brain lysate. Conclusion: Data indicates the potential interaction of Disc1 and Gas7 protein in adult brain. The study highlights the need for further research on Disc1–Gas7 protein interaction in brain development and neuro-disorders.
Review of intervertebral hernia disease treatment methodologies:
Key emphasis on the oxygen-ozone therapy as a method with
multifactorial influence
Authors: Baranova Iryna , Postovitenko Olga , Postovitenko Kateryna , Iliuk Iryna , Osypenko Iryna 
Published: May 2022

IntroductionLow back pain is one of the most common causes of short-term, and sometimes long-term, disability in the population younger than 45 years old. Approximately 60% to 80% of the population in developed countries experience back pain in various locations (neck, mid and lower back) at least once in their lifetime. Guidelines regarding back pain treatment are undergoing constant modifications and improvements. The relevance of dorsalgia as a significant medical problem and its management is shown by the increased number of recently published papers, which has tripled in the past several years (from 22% to 65%).AimTo analyze the most critical risk factors of the degenerative intervertebral disk disease, and to review the effectiveness of invasive and noninvasive methods of treatment of the lower back pain syndrome.Material and methodsRecently published papers focusing on invasive and noninvasive treatments of low back pain syndrome.Results and discussionSurgical intervention as a single method of back pain treatment is indicated in a small number of cases. The risk of repeated surgeries for intravertebral disk herniation should be considered before any surgical intervention. A wide variety of treatment options allows to choose the most effective approach based on individual needs.ConclusionsConservative, noninvasive approach has shown to be an effective alternative for lower back pain and radiculopathy treatment. It has been determined that ozone therapy is an appropriate, relevant, and affordable treatment method for patients with vertebral degenerative changes and intravertebral disk diseases.
Are CMOS Operational Transconductance Amplifiers Old Fashioned? A Systematic Review
Authors: Aparecido da Silva Braga Rodrigo , Moreira e Silva Paulo Marcio , Bicudo Karolak Dean 
Published: May 2022

Operational Transconductance Amplifiers (OTAs) are essential building blocks in analog circuits. Since the early years of integrated circuit science, OTAs have been used in industry and researched in academia. Over the years, a number of techniques and approaches to OTA design have been observed in the literature. With this systematic review, we aim to provide a overview of top journal papers published from 2017 to 2021 containing OTA design. In our investigation we initially found 128 manuscripts and 24 primary studies of OTA design. A set of 10 different techniques have been found. Furthermore, we also evaluate used technology, inversion level and characterization process. With this study we contribute to highlight recent OTA design innovations.
Having the First-Year as Overseas Students: Intercultural Communication as Identity Negotiation of Indonesian Ph.D. Muslim Women Students in the United States
Authors: Ali Mukti , Arifin Win Listyaningrum , Muttaqin Zaenal 
Published: May 2022

This study examined the first-year intercultural communication experiences of Indonesian Ph.D. Muslim women students in the United States as their identity negotiation. The following questions were addressed using Ting Toomey’s intercultural communication theory: What problems do Indonesian Ph.D. Muslim women students face in their new environment in the United States? How do they use intercultural communication as an adaptive strategy? And, to what extent can this intercultural communication skill affect their academic achievement as international students? Using an ethnographic approach, data were obtained through online observations and interviews via WhatsApp and Skype video calls with 11 Indonesian Ph.D. Muslim women students regarding their first-year experiences in the United States. According to the findings of this study, their ability in intercultural communication in their first year becomes the primary capital for their lives during their stay to complete their study. Their experience has turned into knowledge, motivation, and skills that turn out to be beneficial in facing challenges.