bluuebunny/crossref_metadata_2025_split huggingface dataset:
Legal aspects of ensuring environmental safety in the field of protection against the negative impact of water
Authors: Amashukeli S. A. 
Published: August 2022

In the article legal problems of ecological safety in the sphere of the protectionfrom negative impact of water are considered. On the base the comprehensive analysis of strategic plan documents in the field water relations and ecological safety, and also existing water and ecological legislation the author has shown the relevance of the protection from negative impact of water in Russia, the place of the protection from negative impact of water in the structure of ecological safety, the correlation of legislation on population and territoryprotection in emergencies and ecological, water, other natural resource legal rules in the sphere, problems of determine the criteria for categorizing types of negative impact of water are examined.The author gives a legal assessment of current state of methods of the protectionfrom negative impact of the water legal regulation, allocation of power and liability for the development and the implementation of measures to prevent the negative impact of water, analyses recent water legislative changes. The authorconcludes what despite high significance and the complex institution of the protection from negative impact of water, a unified approach to conception of types of negative impact of water and the principle of comprehensiveness of the application of methods of protection from its is absent. Problems of ecological regulation of negative impact of water gaps in the law and the responsibility for the engineering protection remain relevant.
Application of the transformed-interview method in investigation of sexual crimes in Ukraine
Authors: Ivanchenko Andreyanna , Safin Oleksandr , Timchenko Oleksander , Khrystenko Vitalii  
Published: August 2022

The crime detection of sexual violence needs to be optimized and improved. This study aims to substantiate, elaborate, and apply in practice the method of a transformed interview (based on mathematical modeling) to obtain information about sexual violence. For the first time the transformed-interview method was used while studying the hidden (latent) victims of sexual violence who do not want to report a crime to law enforcement agencies because they do not want the fact of violence against them to be made public. Participated 2570 Ukrainian women of different social status, 16-35 years old. It was found that the increase of intermediaries during the information transmission reduces reliability of the information about crimes against the person’s sexual inviolability. While investigating such types of crimes the needed information can be obtained with a higher degree of reliability not from the victim, but from her closest surroundings. The transformed-interview method proved to be an effective tool to extract the information related to the behavior of both the offender and his victim. This method shows reliability and makes it possible to reduce the latency of most crimes in the situation of the victim’s refusal to testify at the re-trial investigation.
Learning Taxonomy of Islamic Education: The Development of Aql and the Brain in Quran from a Neuroscience Perspective
Authors: Suyadi  
Published: August 2022

The hierarchical thinking concept in the Islamic education field is based on theological and philosophical beliefs. Up to now, this concept is not yet proven scientifically and neurobiologically. As a result, Islamic education does not yet have a learning taxonomy that accommodates the effective and spiritual aspects of developing students' intellectual potential. Consequently, it forced its system to apply Bloom’s taxonomy which focuses only on the cognitive part. With the rising of new theories, especially neuro-theology, neuro-philosophy, and neuro-education, emerge the opportunities to connect hierarchical thinking in Islamic education with these three theories. This research aims to compile a learning taxonomy of Islamic education based on neuroscience, accommodating the emotional, intellectual, and spiritual aspects. This research is a systematic review, which integrates, interprets, and synthesizes the hierarchical thinking concept with neuro-theology, neuro-philosophy, and neuro-education. The result shows that hierarchical thinking in Islamic education has neuro-physiological with six brain components: temporal lobe, parietal association cortex-temporal-occipital, limbic system, cingulate gyrus, prefrontal context, and prefrontal association cortex. These six components of the brain have relevance to hierarchical thinking and bloom taxonomy, namely remember (dzikir), understand (nazhr), apply (‘ilm-amal), evaluate (muhasabah); analyze (fikr), and create (ijtihad). Thus, the brain's six components and hierarchical thinking can be narratively synthesized into a learning taxonomy of Islamic education. In the future, this finding could become theoretical discourse because hierarchical thinking, neuro-theology, neuro-philosophy, and neuro-education emerge the further development of learning taxonomy in Islamic education.
Stability of cyber dating victimization and psychological adjustment in adolescents: a short-term longitudinal study
Authors: Rodríguez-deArriba María-Luisa , Muñoz-Fernández Noelia , Sánchez-Jiménez Virginia 
Published: August 2022

The effect of cyber dating victimization on adolescents’ adjustment is understudied. The present study aimed to analyze the impact of cyber dating victimization on antisocial behavior, anxious depressive symptoms, and stress management according to their frequency and stability over time. In the study, 453 Spanish students aged between 12 and 19 years (52.5% girls) with sentimental experience completed surveys in a two-time longitudinal study six-month apart. Cyber dating victimization predicted a worse stress management. Regarding stability, four cyber dating victimization groups were found: non-cyber victims, past cyber victims, recent cyber victims, and stable cyber victims. The results indicated that recent cyber victims worsen their levels of antisocial behavior and anxious depressive symptoms coinciding with the moment of cyber dating victimization. Stable cyber victims showed worse scores in all the study variables over time. This study highlights the impact that cyber dating victimization has on adolescents’ psychological adjustment. These results address the need to develop psychoeducational interventions aimed to prevent cyber dating victimization, favoring adolescents’ healthy development and the improvement of the school life.
MANAJEMEN PESERTA DIDIK DALAM PENINGKATAN MUTU LULUSAN PADA MADRASAH DINIYAH HIDAYATUL MUBTADIIN PAGOTAN
Authors: Christianto Anwar , Evi Muafiah  
Published: August 2022

Banyak masalah timbul akibat rendahnya mutu lulusan. Di antara penyebab rendahnya mutu lulusan adalah belum diterapkannya manajemen peserta didik yang baik. Madrasah Diniyah sebagai lembaga pendidikan keagamaan tengah berupaya berinovasi agar tidak tertinggal. Manajemen peserta didik diperlukan dalam upaya mengoptimalkan pengaturan terhadap peserta didik mulai dari masuk hingga kelulusan, guna meningkatkan daya saing lembaga pendidikan di madrasah diniyah. Madrasah Diniyah Hidayatul Mubtadiin Pagotan telah menerapkan pengaturan peserta didik berdasarkan manajemen peserta didik dalam meningkatkan mutu lulusannya. Penelitian ini bertujuan untuk menjelaskan pelaksanaan manajemen peserta didik serta kontribusi pelaksanaan manajemen peserta didik dalam peningkatan mutu lulusan pada Madrasah Diniyah Hidayatul Mubtadiin Pagotan. Metode penelitian menggunakan pendekatan kualitatif dan jenis penelitiannya adalah single case study. Prosedur pengumpulan data menggunakan wawancara, observasi dan dokumentasi. Analisis data menggunakan analisis menurut Miles Matthew dan A. Michael Huberman. Hasil penelitian ini adalah pelaksanaan manajemen peserta didik meliputi empat tahap, yaitu planning meliputi analisis kebutuhan peserta didik menyesuaikan daya tampung, penyusunan program; organizing meliputi rekruitmen dengan pembentukan panitia dan pembuatan brosur; actuating meliputi penerimaan dengan sistem promosi dan seleksi, seleksi menggunakan tes tulis, lisan dan praktik, orientasi dilakukan sehari dengan pemberian informasi dan arahan terakit aturan dan tata tertib madrasah, pengelompokkan dengan sistem kelas, pembinaan dan pengembangan meliputi kegiatan kurikuler dan ekstrakurikuler; controlling yang meliputi pencatatan kehadiran dan ketidakhadiran dalam buku absensi, pencatatan dan pelaporan ditulis dalam formulir pendaftaran, buku induk, klapper, buku nilai, rapot dan ijasah; kontribusi pelaksanaan manajemen peserta didik yakni meningkatkan prestasi akademik, prestasi non akademik dan kualitas lulusan.
Strategi Program Kemitraan Madin Ali Adam Coper Jetis Ponorogo
Authors: Rachmawati Ani , Rohmanu Abid 
Published: August 2022

Penelitian ini dilatarbelakangi oleh masih rendahnya mutu pendidikan Madrasah Diniyah (Madin). Penyebabnya adalah –untuk menyebut sebagian – kurangnya program kemitraan Madrasah. Menyadari hal tersebut, beberapa Madrasah melakukan berbagai program strategis, salah satunya adalah rintisan dan pengembangan jejaring kemitraan dengan lembaga Bimbingan Belajar Four F4st yang notabene-nya adalah berkaitan dengan materi nonagama (umum). Fenomena menarik ini ada pada Madin Ali Adam Coper Jetis Ponorogo. Lebih lanjut, penelitian ini bertujuan untuk: 1) Mendeskripsikan pelaksanaan program kemitraan di Madin Ali Adam; 2) Mengidentifikasi prinsip dan nilai-nilai yang melatarbelakangi program kemitraan. Untuk tujuan-tujuan tersebut, pendekatan kasus (single case study) dipakai dengan analisis-analisis yang bersifat kualitatif. Data dikumpulkan dengan teknik wawancara mendalam, observasi dan dokumentasi. Sebagai basis analisis, peneliti menggunakan konsep dan nilai-nilai kemitraan yang ditawarkan oleh Tony Lendrum. Berdasar analisis data penelitian ini menyimpulkan tiga hal: 1) Praktik kemitraan di Madin Ali Adam bersifat paradigmatic, yakni dilakukan dengan penumbuhan paradigma integrasi keilmuan (umum dan agama) dan kesadaran pentingnyadistingsi dan kekhasan untuk tumbuh kembangnya lembaga Madin; 2) Program kemitraan Madin Ali Adam diusung dengan berpegang pada prinsip kejujuran, trust, integritas dan pelayanan;
A novel twelve-gene signature to evaluate neoadjuvant chemotherapy response and predict prognosis in breast cancer
Authors: Wu Jin , Tian Yuan , Liao Bin , Zheng Hong , Liu Wei , Yan Yuzhao , Hu Ying , Wang Minghao , Tang Peng 
Published: August 2022

Abstract
Background
Accurate evaluation of breast cancer response to neoadjuvant chemotherapy (NAC) provides important information about systemic therapies, which elucidates tumor biology and prognosis and guides further therapies. Gene profiles overcome the limitations of some indicators of the classical pathological evaluation criteria and the subjectivity of observation, but are complicated and expensive. Therefore, it is essential to develop a more accurate, repeatable, and economical evaluation approach for NAC responses.
Methods
We analyzed the transcriptional profiles of epirubicin-resistant breast cancer cell lines and the tumors derived from NAC-resistant patients from the GEO25066 dataset. We initially screened common significantly differentially expressed genes and constructed a NAC response risk model using LASSO regression and univariate and multivariate analyses. Bioinformatics Analysis were performed to find the differences in bioinformatic features of tumor cells, immune characteristics, and prognosis between the high- and low-risk groups. We screened candidate drugs that could reverse chemotherapy resistance in breast cancer by the Connectivity Map database. Cytotoxicity assay and TUNEL assay were performed to verify the killing effect of drug candidates on drug-resistant breast cancer cells.
Results
Thirty-six genes were commonly up/down-regulated in both the chemo-resistant tumors and cell lines, compared to the sensitive tumors and wild-type cell lines. We obtained a risk model composed of 12 genes trough LASSO regression. The risk model divided patients into high- and low-risk groups. Univariate and multivariate Cox regression analyses suggested that the risk score is an independent prognostic factor for the evaluation of NAC response to breast cancer. Tumors in these risk groups exhibited significant differences in molecular biological characteristics, tumor-infiltrating lymphocytes, and immunosuppressive molecule expression. Our results suggested that the risk score was also a good prognostic factor for breast cancer. Finally, our results suggest that pravastatin, isocarboxazid, imexon, axitinib, and crizotinib could inhibit or kill chemoresistant cells.
Conclusion
A novel 12 gene-signature could be used to evaluate NAC response and predict prognosis in breast cancer.
Association between the levels of nurse-doctor interprofessional collaboration and in-patient mortality: A systematic review
Authors: Pantha Sandesh , Jones Martin , Moyo Nompilo , Pokharel Bijaya , Kushemererwa Diana , Gray Richard 
Published: August 2022

Abstract
BackgroundThe level of nurse-doctor interprofessional collaboration may influence patient outcomes, including mortality. To date, no systematic reviews have investigated the association between the amount of nurse-doctor collaboration and inpatient mortality.MethodsA systematic review. We included studies that measured the amount of nurse-doctor interprofessional collaboration and in-patient mortality. Five databases (MEDLINE, EMBASE, PsycInfo, CINAHL and the Cochrane register) were searched in June 2019 and February 2021. Two researchers undertook title and abstract and full-text screening. Risk of bias was determined using the Effective Public Health Practice Project (EPHPP) measure. ResultsSix documents from three observational studies met the inclusion criteria for the review. Participants included 191 doctors, 29591 nurses, and 1.32 million patients. Included studies had a high risk of bias. Of the three included studies, one reported a significant association and one no association between nurses’ reports of the amount of interprofessional collaboration. Although meeting inclusion criteria the third study did not test this association.ConclusionWe found no high-quality evidence to suggest the amount of nurse-doctor interprofessional collaboration was associated with mortality in medical and surgical inpatients. There is a need for further high-quality research to evaluate the association between the amount of nurse-doctor interaction and patient outcomes.Systematic review registrationPROSPERO CRD42019133543
Estimation of Monthly Sunshine Duration Using Satellite Derived Cloud Data
Authors: Kaba Kazım , Erdi Erdem , Avcı Mutlu , Kandırmaz H. Mustafa 
Published: August 2022

Abstract

Sunshine duration (SD) is one of the critical meteorological parameters used in different fields of application such as climate, renewable energy and agriculture. In this respect, determination and/or estimation of the temporal and spatial variability of SD is critical. Meteorological satellite data/products can be used for estimating SD and in constructing their maps due to their frequent observation of large areas at once. In this study, a multilayer perceptron type artificial neural network model was built to estimate the monthly mean SD for Turkey using the EUMETSAT CM SAF (Satellite Application Facility on Climate Monitoring) CFC (Cloud Fractional Coverage) and CTY (Cloud Type) data, GMTED2010 (Global Multi-resolution Terrain Elevation Data) data, month number and daylength. The datasets of 45 stations, spanning nine years (2005–2013), were used for training the model and 12 stations for testing and validating the simulated values. We have compared the results of our model with the ground-measured values for the whole period under consideration and the root mean square error (RMSE), mean absolute error (MAE), mean bias error (MBE) and the coefficient of determination (R2) were found as 0.7803 h, 0.6206 h, 0.1751 h and 0.9387, respectively. It has been shown that using the new generation cloud products such as CFC and CTY, elevation data such as GMTED2010 and daylength, it is possible to predict the SD for regions under the coverage of the satellite, in case no measurement is possible or may be unreliable, without needing any measured meteorological data.
Effects of Local Palm Oil Mill Effluent on the Histology of Gill, Liver, Kidney, Heart and Muscle and Its Hematological Effects on African Cat Fish, Clarias Gariepinus
Authors: AFOLABI OLUNIYI ADEDIRAN , Adewoye Solomon O. , Afolabi Folakemi D. , Ishola Oluwaseun A. 
Published: August 2022

Abstract
Palm oil mill effluent (POME) is one of the major sources of pollutant produced during oil palm processing. POME in water significantly affects the ability of fishes to detect and respond to chemical stimulus. The aim of this study is to examine the toxicological effects of POME with emphasis on the histopathology of the gills, liver, kidney, heart and muscle as well as the hematological effects. African catfish, Clarias gariepinus of mean weight 300g and standard length 18-21cm were exposed to varying concentrations 0.01, 0.03, 0.05, 0.07 and 0.09 ml/l of POME in duplicates for 14 days to determine the toxicity of POME. 110 healthy fishes were randomly placed into eleven rearing tanks of 100 litres capacity (dimension 50 cm x 25 cm x 25 cm) and filled with 40 litres non-chlorinated water at 10 fishes per tank (one tank for control and two tanks each for each concentration)Histopathological examination of the liver after 14 days of exposure revealed lesions which ranged from necrosis, vacuolation and diffused congestion of cells that deteriorate more with increase in POME effluent concentration. Toxic reactions were observed during the experiment. POME is harmful to aquatic organisms, according to the findings of this study, hence its discharge into bodies of water without sufficient treatment should be avoided.
Scintillation performance of Ince-Gaussian beam in atmospheric turbulence
Authors: BAYRAKTAR Mert 
Published: August 2022

Abstract
Scintillation behavior of Ince-Gaussian(IG) beam is studied in this paper. Split step propagation model is applied to find scintillation index. Our results reveal that beam order and degree have strong effect on scintillation under strong turbulent conditions. In addition to these parameters, ellipticity plays a vital role on scintillation characteristics especially in weak turbulent regime. Significant amount of degradation in scintillation attracts the attention. Among IG beam settings, scintillation index of even modes is less comparing with odd modes. Therefore, it is anticipated that performance of optical wireless communication systems increases when IG beam is used.
High expression of AZGP1 is associated with poor prognosis in colorectal cancer
Authors: Liu Xibo , Li Zhenjun , Ge Weiting , Wen Fei , Zheng Shu , Chen Lirong 
Published: August 2022

Abstract
Background
Alpha-2-glycoprotein 1, zinc-binding (AZGP1) is a 41 kDa secreted glycoprotein that has been considered as a potential prognostic biomarker. High expression of AZGP1 in serum is considered to be an indicator of poor prognosis in CRC, however further validation in tissue specimens is lacking.
Methods
We detected the expression level of AZGP1 in 859 CRC patients and 210 normal mucosa samples by immunohistochemistry and analyzed the relationship between AZGP1 expression and clinicopathological parameters of CRC patients. The relationship between AZGP1 and overall survival of patients was also analyzed to verify the prognostic value of AZGP1 in CRC patients. Multivariate analysis of prognostic factors in CRC patients using Cox proportional hazards regression models.
Results
The high expression rate of AZGP1 in colorectal adenocarcinoma was 48.4% higher than that in adjacent mucosal tissues and 13.3% (P < 0.001). The expression level of AZGP1 was related to the depth of invasion (P < 0.001), lymph node metastasis (P = 0.023), distant metastasis (P = 0.002) and pTNM stage(P = 0.003). Univariate analysis found that histological type, differentiation, invasion, lymph node metastasis, distant metastasis, pTNM stage and AZGP1 expression were associated with the prognosis of CRC patients (all P < 0.05). Multivariate analysis suggested lymph node metastasis (95% CI: 0.331–0.775, HR: 0.506, P = 0.002), distant metastasis (95% CI: 0.126–0.293, HR: 0.192, P < 0.001) and AZGP1 (95% CI: 0.262–0.637, HR: 0.408, P < 0.001) were independent prognostic indicators.
Conclusion
AZGP1 is a useful indicator for predicting the prognosis of CRC. Its predictive effect is weaker than that of lymph node metastasis and distant metastasis.
A Novel Defined Pyroptosis-Related Gene Signature for Predicting Prognosis of Acute Myeloid Leukemia
Authors: Wang Fan 
Published: August 2022

Abstract
Background: Pyroptosis is an inflammatory form of programmed necrotic cell death, but its potential prognostic value in acute myeloid leukemia (AML) still remains unclear. In this study, we aimed to construct a pyroptosis genes related signature that can effectively predict the prognosis of AML patients.Methods: Based on the available AML data from TCGA and TARGET dabases, a pyroptosis-related prognostic model was constructed by performing a LASSO Cox regression analysis, and the predictive value of the model was validated in a GEO cohort. The impact of pyroptosis on the immune microenvironment of AML was explored as well. The chemotherapeutic drug Sensitivity was further evaluated.Results: A 10-gene signature model was constructed to effectively predict AML prognosis, which showed that patients with low-risk score had a significantly better prognosis than the high-risk group, and receiver operator characteristic (ROC) analysis proved superior performance of the prognostic model. The model was further verified well in an external GEO cohort. Multivariable Cox regression analysis showed that in addition to age, the risk score was also an independent poor survival factor for AML patients. Moreover, the high-risk group generally had higher activity of cytolytic activity and increased levels of infiltrating immune cells including tumor-infiltrating lymphocytes (TILs) and regulatory T cells (Tregs). Additionally, low-risk AML patients may get better response from the traditional chemotherapeutic drugs (cytarabine, doxorubicin, docetaxel and etoposide).Conclusion: A pyroptosis-related gene signature can independently predict the prognosis of AML patients with sufficient predictive power, and pyroptosis plays an important role in the immune microenvironment of AML, which may be used to develop a new effective immunotherapeutic method for AML in the future.