bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research of working bodies a continuous action earthworks machines
Authors: Gorbatyuk Ievgenii , Pelevin Leonid , Terentyev Оlexander , Svider'ky Anatolij 
Published: March 2022

Earthmoving equipment in highly developed countries is a leading place among self-propelled and trailed equipment for various purposes.
The basis of such equipment are scientific and technical principles of creation of high-speed low-energy technologies and machines for destruction of natural and artificial environments (soils, rocks, mules, reinforced concrete, bricks, etc.) in various conditions (ground - road, cultivation of agricultural lands, engineering, military and emergency rescue work, cleaning of soils from pollution, reclamation, creation of trenches, canals, which underground - mining, tunnel construction, etc.
Continuous action machines are such machines in which the working body contacts with the object of influence (soil) during the whole time of operation and all technological operations are performed simultaneously and continuously.
Working bodies of continuous-action machines have the ability to develop strong soils without preliminary loosening
During the continuous operation of machines, the process of their work is divided into two processes: the process of cutting soil into slaughter and the process of excavation of soil from the cutting zone, followed by its ejection from slaughter.
The article provides an overview of new dynamic working bodies of shrew machines. The descriptions, drawings, highlighted the main disadvantages and advantages. As a result of the synthesis of existing working bodies, a new dynamic working body was developed.
EWALDUS ALEXIUS TAUS PERSEPSI MASYARAKAT TERHADAP PENGEMBANGAN AIR TERJUN BONEMNAISIO SEBAGAI OBYEK WISATA
Authors: TAUS EWALDUS ALEXIUS 
Published: March 2022

Penelitian ini dilakukan di Desa Tun-tun, Kecamaatan Miomaffo Timur, Kabupaten Timor Tengah Utara. Desa ini memiliki keindahan alam yang belum dikelola dan dimanfaatkan dengan baik yaitu keindahan alam air terjun Bonemnaisio yang dipandang memiliki potensi sebagai tempat pariwisata. Penelitian ini menggunakan metode penelitian deskriptif kualitatif, penelitian ini akan menjelaskan sifat dari obyek yang diteliti dengan teknik pengumpulan data dengan cara penelitian kepustakaan, penelitian lapangan, Wawancara dan dokumen. Teknik analisis data yang digunakan dalam penelitian ini merupakan teknik analisis data model interaktif yang dimulai dari proses pengumpulan data (data collection), reduksi data (data reduction), penyajian data (display data), dan pengambilan kesimpulan dan verifikasi (conclusions drawing/ verifying).
Hasil penelitian ini menunjukan bahwa air terjun Bonemnaisio berpotensi sebagasi obyek wisata desa yang perlu dikembangkan oleh pemerintah terutama pemerintah desa Tun-tun. Sektor parawisata juga termasuk salah satu penujang pembangunan disuatu tempat Maka masyarakat berpresepsi bahwa air terjun Bonemnaisio ini memang layak dan pantas dikembangkan sebagai obyek wisata desa. Namun saat ini kenyataanya dari pihak pemerintah setempat belum mengelola air terjun tersebut dengan baik. Saran yang diajukan adalah perlunya kebijakan tentang pengembangan objek wisata dan sosialisasi untuk mendapatkan dukungan masyarakat, objek wisata dijadikan sebagai objek alternatif, pembanguinan inrastruktur dan sarana penunjang.
PERANAN TOKOH ADAT DALAM MELASTARIKAN KEBUDAYAAN LOKAL DI DESA LAKANMAU
Authors: Tahan Anastasia , Kehik Bernardus Seran , Mael Medan Yonathan 
Published: March 2022

Penelitian ini bertujuan untuk memberikan gambaran mengenai peranan tokoh adat dalam melestarikan kebudayaan lokal di Desa Lakanmau. Masalah tentang pengaruh kebudayaan asing terhadap kebudayaan lokal, di Desa Lakanmau Kecamatan Lasiolat Kabupaten Belu, yaitu masuknya budaya asing (dance) menyebabkan kebudayaan lokal menjadi pudar.Pemahaman tentang keberadaan manusia tidak terlepas dari relasi dengan sesama untuk melestarikan kebudayaan lokal tebe, bidu, likurai dan gong. Peran tokoh adat norma kedudukan perilaku masyarakat. Metode yang digunakan dalam penelitian ini adalah metode deskriptif kualitatif. Selanjutnya yang menjadi variabel dalam penelitian ini adalah Peran Tokoh Adat Dalam Melestarikan Kebudayaan Lokal di Desa Lakanmau yang kemudian di ukur melalui indikator-indikator dan dalam menganalisa variabel ini penulis analisa deskriptif kualitatif dengan teknik pengumpulan datanya adalah observasi, angket, wawancara dan dokumentasi.Kesimpulan yang diambil dari hasil penelitian adalah peran tokoh adat dalam melestarikan kebudayaan lokal di Desa Lakanmau telah menjalankan peran tokoh adat yang ditandai dengan kesepakatan untuk melestarikan kebudayaan lokal dengan baik. Berdasarkan kesimpulan di atas, maka disarankan kepada peranan tokoh adat Desa Lakanmau tetap meningkatkan tugas dalam melestarikan kebudayaan lokal di Desa Lakanmau.
KETERWAKILAN PEREMPUAN PADA LEMBAGA LEGISLATIF PERIODE 2019-2024 DI KABUPATEN TIMOR TENGAH UTARA
Authors: NAHAS YUBLINA MARIA GONDULFA 
Published: March 2022

Saat ini masalah ketimpangan gender masih kita temukan di Indonesia dan hal ini bisa kita lihat dalam berbagai lingkup kehidupan, baik politik maupun sosial. Kepentingan yang terjadi akhirnya menimbulkan ketidakadilan dan kesetaraan gander. Tuntutan pemenuhan minimal 30% keterwakilan perempuan diranah politik, khususnya pada Lembaga Legislatif sampai saat ini masih menjadi salah satu masalah yang fundamental. Penelitian ini dilakukan untuk mengetahui keterwakilan perempuan pada lembaga legislative periode 2019-2024 di Kabupaten Timor Tengah Utara. Dengan rumusan masalah Bagaimana keterwakilan perempuan pada lembaga legislative periode 2009-2024 di Kabupaten TTU dapil dua Insana?. Metode yang digunakan dalam penelitian ini adalah metode kualitatif. Hasil penelitian ini menunjukan bahwa keterwakilan perempuan pada lembaga legislative periode 2009-2024 di Kabupaten TTU, sama sekali tidak ada karena caleg perempuan di Kabupaten TTU tidak bisa mencapai suara signifikan atau tidak terpilih. Peneliti menyarankan untuk masyarakat agar kedepan dapat menentukan hak pilihnya kepada caleg perempuan sehingga dapat memperjuangkan hak-hak perempuan, untuk caleg perempuan agar pemilu legislative mendatang mempersiapkan strategi yang tepat dan mempersiapkan diri secara matang, kepada caleg agar kedepan dapat mempersiapkan finansial secara baik, dapat membangun jaringan sejak dini baik itu melalui kegiatan kemasyarakatan maupun kegiatan kemanusiaan, untuk caleg perempuan agar dapat meningkatkan kepercayaan diri
Comparative Study on the Efficiency of Mercury Removal From Wastewater Using Bacterial Cellulose Membranes and Their Oxidized Analogue
Authors: Suárez-Avendaño D. , Martínez-Correa E. , Cañas-Gutierrez A. , Castro-Riascos M. , Zuluaga-Gallego R. , Gañán-Rojo P. , Peresin M. , Pereira M. , Castro-Herazo C. 
Published: March 2022

A comparative study was conducted on the efficiency of mercury removal using bacterial nanocellulose (BNC) membranes obtained from the fermentation of the microorganism Komagataeibacter medellinensis, in contrast with its oxidized analog obtained by modifying the bacterial nanocellulose membranes via oxidation with 2,2,6,6-Tetramethylpiperidine-1-oxyl. Both types of membranes (modified and unmodified) were characterized to identify variations in the Physico-chemical parameters after modification. FTIR spectra confirmed the chemical modification of cellulose in all reaction conditions by the presence of a new characteristic band at ∼1730 cm−1, corresponding to the new carboxylic groups produced by the oxidative process, and the decline of the band at ∼1,650 cm−1, corresponding to the hydroxyl groups of the C6 carbon. While the XRD profiles indicated that the percentage of BNC crystallinity decreased and the SEM images showed that the nanoribbon network was interrupted as the amount of oxidizing agent increased. The kinetics of mercury removal from both types of membrane was evaluated by calculating the concentration of mercury at different times and establishing a mathematical model to describe the kinetics of this process. The modified membranes improved significantly the adsorption process of the metal ion and it was found that the modification that results in the greatest adsorption efficiency was BNC-m 7.5 with a value of 92.97%. The results obtained suggest that the modification of the bacterial nanocellulose membranes by oxidation transcendentally improves the mercury removal capacity, outlining the modified membranes as an excellent material for mercury removal in wastewater.
Gut Microbiota-Related Inflammation Factors as a Potential Biomarker for Diagnosing Major Depressive Disorder
Authors: Bai Shunjie , Bai Huili , Li Detao , Zhong Qi , Xie Jing , Chen Jian-jun 
Published: March 2022

ObjectiveAlthough many works have been done, the objectively measured diagnostic biomarkers are not available. Thus, we conducted this study to identify potential biomarkers for objectively diagnosing depression and explore the role of gut microbiota in the onset of depression.MethodsMajor depressive disorder (MDD) patients (n=56) and demographic data-matched healthy controls (HCs) (n=56) were included in this study. The gut microbiota in fecal samples and inflammation-related factors in serum were measured. Both univariate and multivariate statistical analyses were performed to identify the differential gut microbiota and inflammation-related factors.ResultsFinally, 46 differential operational taxonomic units (OTUs) (60.9% OTUs belonging to Firmicutes) and ten differential inflammation-related factors were identified. Correlation analysis showed that there were significant correlations between 14 differential OTUs (9 OTUs belonging to Firmicutes and 5 OTUs belonging to family Lachnospiraceae under Firmicutes) and seven differential inflammation-related factors. Meanwhile, 14 differential OTUs (9 OTUs belonging to Firmicutes and 5 OTUs belonging to family Lachnospiraceae under Firmicutes) and five differential inflammation-related factors (adiponectin, apolipoprotein A1, alpha 1-antitrypsin, neutrophilicgranulocyte count/white blood cell count and basophil count) were significantly correlated to depression severity. A panel consisting of these five differential inflammation-related factors could effectively diagnose MDD patients from HCs.ConclusionsOur results suggested that Firmicutes, especially family Lachnospiraceae, might play a role in the onset of depression via affecting the inflammation levels of host, and these five differential inflammation-related factors could be potential biomarkers for objectively diagnosing MDD.
Social Determinants of Disparities in Mortality Outcomes in Congenital Heart Disease: A Systematic Review and Meta-Analysis
Authors: Tran Richard , Forman Rebecca , Mossialos Elias , Nasir Khurram , Kulkarni Aparna 
Published: March 2022

BackgroundSocial determinants of health (SDoH) affect congenital heart disease (CHD) mortality across all forms and age groups. We sought to evaluate risk of mortality from specific SDoH stratified across CHD to guide interventions to alleviate this risk.MethodsWe searched electronic databases between January 1980 and June 2019 and included studies that evaluated occurrence of CHD deaths and SDoH in English articles. Meta-analysis was performed if SDoH data were available in &gt;3 studies. We included race/ethnicity, deprivation, insurance status, maternal age, maternal education, single/multiple pregnancy, hospital volume, and geographic location of patients as SDoH. Data were pooled using random-effects model and outcome was reported as odds ratio (OR) with 95% confidence interval (CI).ResultsOf 17,716 citations reviewed, 65 met inclusion criteria. Sixty-three were observational retrospective studies and two prospective. Of 546,981 patients, 34,080 died. Black patients with non-critical CHD in the first year of life (Odds Ratio 1.62 [95% confidence interval 1.47–1.79], I2 = 7.1%), with critical CHD as neonates (OR 1.27 [CI 1.05-1.55], I2 = 0%) and in the first year (OR 1.68, [1.45-1.95], I2 = 0.3%) had increased mortality. Deprived patients, multiple pregnancies, patients born to mothers &lt;18 years and with education &lt;12 years, and patients on public insurance with critical CHD have greater likelihood of death after the neonatal period.ConclusionThis systematic review and meta-analysis found that Black patients with CHD are particularly vulnerable for mortality. Numerous SDoH that affect mortality were identified for specific time points in CHD course that may guide interventions, future research and policy.Systematic Review Registration[https://www.crd.york.ac.uk/PROSPERO/display_record.php?ID=CRD42019139466&amp;ID=CRD42019139466], identifier [CRD42019139466].
Ticagrelor vs. Clopidogrel in Older Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: Insights From a Real-World Registry
Authors: Zhang Yunnan , Peng Wenxing , Shi Xiujin , Han Jialun , Wang Yifan , Fang Zhenwei , Lin Yang 
Published: March 2022

Background and ObjectivesIt is unclear whether more potent P2Y12 inhibitors are of benefit to older patients who are at high risk for both ischemia and bleeding. We conducted an observational study to compare the clinical outcomes of clopidogrel and ticagrelor uses in older patients with an acute coronary syndrome (ACS).MethodsOlder patients (aged ≥65 years) with ACS who underwent percutaneous coronary intervention (PCI) were divided into clopidogrel-treated and ticagrelor-treated groups. The primary observational endpoint was the occurrence of net adverse clinical and cerebral events (NACCEs) during a 12-month period, which is defined as the composite endpoint of all-cause death, myocardial infarction (MI), stroke, stent thrombosis, urgent coronary revascularization, and clinically significant bleeding. The secondary endpoints were clinically significant bleeding and major adverse clinical and cerebral events (MACCEs).ResultsThis study included a total of 2,611 patients. Of them, 1,636 received clopidogrel and 975 received ticagrelor. Between patients receiving clopidogrel and those receiving ticagrelor, no significant differences were noted in NACCE (8.4 vs. 9.7%, respectively; adjusted hazard ratio [HR], 0.86; 95% confidence interval [CI], 0.66–1.12) or MACCE (7.1 vs. 7.0%, respectively; adjusted HR, 1.13; 95% CI, 0.83–1.55) during the 12-month follow-up period. In contrast, the occurrence of clinically significant bleeding was significantly less in clopidogrel-treated patients compared with that in ticagrelor-treated patients (27, 1.7%, vs. 31, 3.2%, respectively; adjusted HR, 0.42; 95% CI, 0.25–0.69). Stratified analyses revealed no significant association between age (≥75 years vs. &lt;75 years) and treatment condition in terms of primary or secondary endpoints.ConclusionThis study showed that clopidogrel and ticagrelor had comparable net clinical benefits in patients with ACS aged ≥65 years. Additionally, clopidogrel was associated with a significantly lower risk of major bleeding than ticagrelor without an increase in ischemic risk. These findings suggest that clopidogrel is an effective alternative to the more potent P2Y12 inhibitor ticagrelor in older patients.
Effectiveness of Remotely Delivered Interventions to Simultaneously Optimize Management of Hypertension, Hyperglycemia and Dyslipidemia in People With Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Authors: Fernando Malindu E. , Seng Leonard , Drovandi Aaron , Crowley Benjamin J. , Golledge Jonathan 
Published: March 2022

BackgroundRemotely delivered interventions may be more efficient in controlling multiple risk factors in people with diabetes.PurposeTo pool evidence from randomized controlled trials testing remote management interventions to simultaneously control blood pressure, blood glucose and lipids.Data SourcesPubMed/Medline, EMBASE, CINAHL and the Cochrane library were systematically searched for randomized controlled trials (RCTs) until 20th June 2021.Study SelectionIncluded RCTs were those that reported participant data on blood pressure, blood glucose, and lipid outcomes in response to a remotely delivered intervention.Data ExtractionThree authors extracted data using a predefined template. Primary outcomes were glycated hemoglobin (HbA1c), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-c), systolic and diastolic blood pressure (SBP &amp; DBP). Risk of bias was assessed using the Cochrane collaboration RoB-2 tool. Meta-analyses are reported as standardized mean difference (SMD) with 95% confidence intervals (95%CI).Data SynthesisTwenty-seven RCTs reporting on 9100 participants (4581 intervention and 4519 usual care) were included. Components of the remote management interventions tested were identified as patient education, risk factor monitoring, coaching on monitoring, consultations, and pharmacological management. Comparator groups were typically face-to-face usual patient care. Remote management significantly reduced HbA1c (SMD -0.25, 95%CI -0.33 to -0.17, p&lt;0.001), TC (SMD -0.17, 95%CI -0.29 to -0.04, p&lt;0.0001), LDL-c (SMD -0.11, 95%CI -0.19 to -0.03, p=0.006), SBP (SMD -0.11, 95%CI -0.18 to -0.04, p=0.001) and DBP (SMD -0.09, 95%CI -0.16 to -0.02, p=0.02), with low to moderate heterogeneity (I²= 0 to 75). Twelve trials had high risk of bias, 12 had some risk and three were at low risk of bias.LimitationsHeterogeneity and potential publication bias may limit applicability of findings.ConclusionsRemote management significantly improves control of modifiable risk factors.Systematic Review Registration[https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=258433], identifier PROSPERO (CRD42021258433).
Genetic Variants of the BAFF Gene and Risk of Fatigue Among Patients With Primary Sjögren’s Syndrome
Authors: Flessa Christina-Maria , Zampeli Evangelia , Evangelopoulos Maria-Eleftheria , Natsis Vasilis , Bodewes Iris L. A. , Huijser Erika , Versnel Marjan A. , Moutsopoulos Haralampos M. , Mavragani Clio P. 
Published: March 2022

Background/PurposePrimary Sjögren’s Syndrome (SS) is characterized by B lymphocyte hyperactivity with B cell activating factor (BAFF) acting as an important regulator. Single Nucleotide Polymorphisms (SNPs) of the BAFF gene have been implicated in the pathogenesis of several autoimmune diseases characterized by heightened fatigue levels, including primary SS. We aimed to explore potential associations between BAFF SNPs and fatigue status of primary SS patients.MethodsFatigue status was assessed in 199 consecutive primary SS patients (Greek cohort) using the Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-F) scale. Clinical, histological, laboratory, psychometric and personality data were also collected. DNA extracted from peripheral blood of all patients underwent evaluation for the presence of five BAFF SNPs (rs9514827, rs1041569, rs9514828, rs1224141, rs12583006) by PCR. To confirm our findings, an independent replicative cohort of 62 primary SS patients (Dutch cohort) was implemented. Finally, 52 multiple sclerosis (MS) patients were served as disease controls (MS cohort). Analysis of BAFF SNPs in association with fatigue levels was performed by the online platforms SNPStats and SHEsis and the SPSS 26 and Graph Pad Prism 8.00 software.ResultsTT genotype of the rs9514828 BAFF polymorphism was significantly less frequent in the fatigued primary SS patients of the Greek cohort compared to the non-fatigued (14.1% vs 33.3%). The corresponding ORs [95%CI] in the dominant and overdominant models were 0.33 [0.15-0.72], p=0.003 and 0.42 [0.23-0.78], p=0.005 respectively. The association remained significant after adjustment for the variables contributing to fatigue in the univariate analysis (OR [95% CI]: 0.3 [0.1-0.9], p=0.026). Accordingly, in the Dutch cohort, there was a trend of lower mental fatigue among patients carrying the TT rs9514828 BAFF genotype compared to their CC counterparts (4.1 ± 2.4 vs 6.0 ± 2.2 respectively, p=0.06). The rs9514828 BAFF SNP was not significantly associated with fatigue in the MS cohort.ConclusionsWe report a novel association between genetic makeup and primary SS-associated fatigue with the rs9514828 TT genotype decreasing the likelihood of fatigue development among these patients. These findings need validation in multi-center studies.
Broadband Polarization Manipulation Based on W-Shaped Metasurface
Authors: Xu Guangyuan , Gao Lei , Chen Yongqiang , Ding Yaqiong , Wang Jun , Fang Yu , Wu Xingzhi , Sun Yong 
Published: March 2022

We present a metasurface consisting of W-shaped resonators to realize broadband reflective linear and circular polarization conversions. We find that the cross polarization conversion ratio for normal incidence is over 0.95 from 9.2 to 18.7 GHz, covering 68.1% of the central frequency. We also show that, the conversion performance is almost insensitive to the angle of incident waves. Furthermore, by simply adjusting the geometrical parameters of the W-shaped metasurface, the broadband circular polarization conversion is also achieved. We emphasize that the bandwidth of axis ratio less than 3.0 dB covers from 10.1 to 17.7 GHz, equivalent to 54.7% relative bandwidth. Due to these broadband and high-efficiency polarization conversion features, our proposal may have a wide application prospect.
The Minimal Subcortical Electronic Threshold Predicts the Motor Deficit and Survivals in Non-Awake Surgery for Gliomas Involving the Motor Pathway
Authors: Ren Xiaohui , Yang Xiaocui , Huang Wei , Yang Kaiyuan , Liu Li , Cui Yong , Guo Lanjun , Qiao Hui , Lin Song 
Published: March 2022

PurposeDirect subcortical motor mapping is the golden criterion to detect and monitor the motor pathway during glioma surgery. Minimal subcortical monopolar threshold (MSCMT) means the minimal distance away from the motor pathway and is critical to decide to continue or interrupt glioma resection. However, the optimal cutoff value of MSCMT for glioma resection in non-awake patients has not been reported discreetly. In this study, we try to establish the safe cutoff value of MSCMT for glioma resection and analyzed its relationship with postoperative motor deficit and long-term survivals.MethodsWe designed this prospective study with high-frequency electronic stimulus method. The cutoff MSCMT of postoperative motor deficits was statistically calculated by receiver operating characteristic (ROC) curve, and its relationship with motor deficit and survivals was analyzed by logistic and Cox regression, respectively.ResultsThe cutoff MSCMT to predict motor deficit after surgery was 3.9 mA on day 1, 3.7 mA on day 7, 5.2 mA at 3 months, and 5.2 mA at 6 months. MSCMT ≤3.9 mA and MSCMT ≤5.2 mA independently predicted postoperative motor deficits at four times after surgery (P &lt; 0.05) but had no effect on the removal degree of tumor (P &gt; 0.05). In high-grade gliomas, MSCMT ≤3.9 mA independently predicted shorter progression-free survival [odds ratio (OR) = 3.381 (1.416–8.076), P = 0.006] and overall survival [OR = 3.651 (1.336–9.977), P = 0.012]. Power model has the best fitness for paired monopolar and bipolar high-frequency thresholds.ConclusionsThis study showed strong cause–effect relation between MSCMT and postoperative motor deficit and prognoses. The cutoff MSCMT was dug out to avoid postoperative motor deficit. Further studies are needed to establish the results above.