bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progress Toward Pilot-Scale Simulation of In-Situ Combustion Incorporating Geomechanics
Authors: Li Y. , Manrique E. J. , Kovscek A. R. 
Published: August 2022

Summary
In-situ combustion (ISC) is a promising thermal enhanced oil recovery method with benefits for deep reservoirs, potentially lesser energy requirements as compared to steam injection, and low opportunity cost. Although successful ISC projects have been developed all over the world, challenges still exist including difficulties in monitoring combustion-front progress in the field, describing multiscale physical processes, characterizing crude oil kinetics fully, and simulating ISC at field scale. This work predicts combustion front propagation and the effect of thermally induced stress at the scale of an ISC pilot project. Reservoir deformation was characterized by a geomechanical model to investigate the correlation of combustion front progress with reservoir and surface deformation. We upscaled the reaction kinetics directly from combustion tube experiments and calibrated the laboratory-scale model compared with experimental measurements. We then upscaled numerical simulation to a 3D geometry incorporating a geomechanical model. The change in scale is significant as the combustion tube is 6.56 ft (2 m) in length, whereas the dimensions of the 3D model are 1,440 ft by 1,440 ft (439 m) by 1,400 ft (427 m). The elastic properties were defined by Young’s modulus and Poisson’s ratio, whereas the plastic properties were defined by a Mohr-Coulomb model. A sensitivity study examined the reliability of the model, showing the reaction progress and geomechanical responses were not significantly impacted by gridblock dimensions and reservoir heterogeneity. Finally, a field-scale model was developed covering an area of 5,960 ft (1817 m) by 4,200 ft (1280 m). We observed successful ISC simulation including ignition as air injection started. The temperature increased immediately to more than 800°C (1,400°F) based on the chemical kinetics implemented. The temperature history indicated that the combustion front propagated from the injection well into the reservoir with an average velocity of 0.16 ft/D (0.049 m/d). A surface deformation map correlated with the progress of ISC in the subsurface. Land surface uplift because of ISC ranges from 0.1 ft (0.03 m) to several feet, depending on the rock properties and subsurface events. This proof-of-concept model indicated strong potential to detect the surface movement using interferometric synthetic aperture radar (InSAR) and/or tiltmeters to monitor dynamically combustion front positions in subsurface.
New Insight into the Spatial Autoregressive Model of Industrial Wastewater Discharge in the Yellow River Basin
Authors: Xia Libo , Wang Zhiliang , Du Shuang , Tian Decun , Zhou Yun 
Published: August 2022

Abstract
This article has carried out a statistical analysis of the industrial wastewater discharge (IWD) and gross regional product (GRP) of 79 cities in the Yellow River Basin from 2003 to 2019. By calculating the Moran index of IWD and GRP, the study has found that a certain spatial autoregressive in space. There is an environmental Kuznets curve (EKC) between the environmental pollution and economic development of cities in the Yellow River Basin, and a spatial autoregressive is modelled by a set of random effects that are assigned a conditional autoregressive prior distribution. In the Bayesian environment, Markov chain Monte Carlo (MCMC) is used for inferencing, and the spatial weight matrix is ​​selected to be U-shaped matrix, and the error of the model is minimized. The parameter posterior distribution results of the model showed that the GRP did not show a significant decline. The modified EKC showed that the discharge of industrial wastewater in the entire Yellow River Basin will be reduced. Generally, cities with high pollutant emissions should learn from other cities to reduce emissions, and cities with low GRP need to increase local economic development.
Early detection of variants of concern via funnel plots of regional reproduction numbers
Authors: Milanesi Simone , Rosset Francesca , Colaneri Marta , Giordano Giulia , Pesenti Kenneth , Blanchini Franco , Bolzern Paolo , Colaneri Patrizio , Sacchi Paolo , De Nicolao Giuseppe , Bruno Raffaele 
Published: August 2022

Abstract
Tools to early detect the emergence of a new variant of concern are essential to develop strategies that contain epidemic outbreaks and their health-economic-social consequences. For example, knowing in which region a variant of concern appears or starts spreading enables prompt actions to circumscribe the diffusion area. This paper presents ‘funnel plots’ as a statistical process control method that can quickly identify regions of a country where the reproduction number is anomalous with respect to the national one, while keeping false alarms under control. Unlike tools whose purpose is to identify rises of Rt, the proposed method detects when a regional Rt behaves differently from the national average and thus represents an abnormal situation that needs to be investigated through cross-cutting research. The method is validated on public COVID-19 data demonstrating its efficacy in the early detection of SARS-CoV-2 variants in India, South Africa, England, and Italy, as well as of a malfunctioning episode of the diagnostic infrastructure in England.
The effect of inflammation and oxidative stress on DNA damage in COVID-19 patients
Authors: Tepebaşı Muhammet Yusuf , İlhan İlter , Temal Esra Nurlu , Sancer Okan , Öztürk Önder 
Published: August 2022

Abstract
COVID-19 disease, which spreads all over the world, is a disease characterized by widespread inflammation and affecting many organs, especially the lungs. The resulting inflammation triggers the formation of reactive oxygen radicals and may cause oxidative DNA damage. A total of 95 patients with positive RT-PCR test and hospitalization were divided into three groups according to the severity of pneumonia as mild, moderate and severe/critical. Inflammation markers (Neutrophil lymphocyte ratio, serum reactive protein, procalcitonin etc.), IL-10 and IF γ levels were detected by enzyme-linked immunosorbent assay method. In the evaluation of oxidative damage, thiol, disulfide and IMA levels were measured spectrophotometrically. In the evaluation of oxidative DNA damage, the tail DNA percent parameter obtained by the comet assay method was used. As a result, we found that total thiol, native thiol and disulfide levels decreased significantly due to the increase in inflammation markers and cytokine levels in the severe/critical group. At the same time, we determined that there was an increase in the tail DNA percent level, that is, DNA damage, due to the increased oxidative effect. As a result, we found that increased inflammation and reactive oxygen species due to the increase in pneumonia increased in those with severe and severe pneumonia, which in turn damaged DNA. We think that it would be useful to follow up the DNA damage in these patients in terms of neurodegenerative diseases and cancer development.
Analysis of atypical orbits in one dimensional linear piecewise-smooth discontinuous map
Authors: Metri Rajanikant , Rajpathak Bhooshan , Pillai Harish K 
Published: August 2022

Abstract
In this paper, boundary regions of 1-D linear piecewise-smooth discontinuous map are examined analytically. It is shown that, under certain parameter conditions, the map exhibits atypical orbits like a continuum of periodic orbits and quasi-periodic orbits. Further, we have derived the conditions under which such phenomena occurs. The paper also illustrate that there exists a specific parameter region in which as parameter is varied, there is a smooth transition from stable to unstable periodic orbits. Moreover, we have derived the expression for the value of parameter at which this transition from stable to unstable periodic orbits occurs. Additionally, the dynamics that exist at this value of parameter is also found out.Mathematics Subject Classification (2020) 39A23 · 39A28 · 39A33
VMPS: A Vector Map Protection Framework Supporting Dynamic Game and Local Desensitization
Authors: Hua Weihua , Xu Heng , Duan Jianchao , Song Jun , Yang Fan 
Published: August 2022

Abstract
Secure sharing of geospatial information has attracted widespread attention in recent years. As a typical geospatial data, vector maps can be used in many fields of national economic and social development. However, there are many security threats to data sharing of vector digital maps, such as tampering, forgery, infringement, data leakages. Due to the complex spatial relation nature, existing data protection solutions are either infeasible or ineffective in such scenarios, especially for the exchange, sharing, and publishing of map data. To address these real security problems, in this paper, we propose a novel vector map protection framework, which introduces the idea of dynamic game and local desensitization. Two basic models and a specific scheme, including an important information protection model, an optimal data desensitization model, and a game-based local desensitization scheme, are presented in this framework. Dynamic game strategies are adopted to effectively measure the utility of players under different decisions. Furthermore, important or sensitive map elements in vector maps are desensitized locally in a controlled and reversible manner, thereby achieving more efficient data protection and secure sharing. A comprehensive evaluation, including desensitization strategies, performance and time consumption, accuracy control and reversibility, is given to show the security and feasibility of the proposed framework.
Production Performance, Defensive, Hygienic, Swarming, and Foraging Behavior of Apis mellifera scutellata bee race
Authors: Tarekegn Alayu , Faji Mulisa , Abebe Alemayehu , Bezabeh Amssalu 
Published: August 2022

Abstract
Honey bee colonies exhibit a wide range of behavioral variations depending on genetic origin and environmental factors. Therefore, the performance evaluation of honey bee races is critical to laying a foundation for future selection and improvement in Ethiopia. Thirty colonies of Apis mellifera scutellata (A.m.scutellata) similar in resources contained in the hive were kept in improved box hives and evaluated through reproductive swarming tendency, foraging activity, defensive behavior, hygienic behavior, brood population, honey production, and absconding behavior during the active season and dearth season. In the study area, the A.m.scutellata race has a higher swarming tendency in the active season, with up to 3.24 queen caps per hive prepared per year. Defensive behavior during the active season takes an average of 25.41second after disturbances and follows up to a 212.20-meter distance. But during the dearth season, the colony slightly took a long time to reach aggressiveness after disturbance (31.28 seconds) and followed the observer for a short distance (45.58 meters). The closed brood production is higher (149 units per hive) during the active season and nectar production units per hive are reduced by 50% as compared to the dearth season. The yielding performance of the race per frame ranged from 1.3 kg to 1.5 kg, and an average of 14 kg of honey per harvest. The A.m.scutellata exhibited an absconding tendency of 34.5% if there was any disruption. A.m. scutellata showed good performance in hygienic behaviors (>95%), but undesirable behaviors in defensive behavior and swarming tendency make it difficult to manage honey bees. However, the race has good performance in foraging and hygienic behaviors. Further, studies of the honey bee race through selection and breeding could be conducted to reduce the higher aggressiveness and swarming tendency of A. m. scutellata to improve production performance.
Fine Structure of the Defense System of Synanceia verrucosa from the Red Sea Egypt.
Authors: Abd-Elrheem Ali 
Published: August 2022

Abstract
The stonefish has an advanced poisonous gland that has a lumen and medulla consisting of connective tissue types. All authors have studied the poisonous gland of stonefish and they give attention to two types of cells only careless transmission semithin. In the present study, we give attention to the whole structures of this gland by an accurate examination of Electron Micrographs in all gland areas. Also, some authors give attention to secretions only and do not give any attention to the complete structure of the poisonous defense system of an animal. In the present study, the sections were taken in different areas as the front gland, and mid, surround the spine for covering all areas to discover any new structure. This study revealed that the stonefish poisonous gland Synanceia verrucosa in the Red Sea has four types of cells called T.A, T.B, T.C, and T.D appear as (first evidence) in semithin only.
Differential binding of CREB and REST/NRSF to NMDAR1 promoter is associated with the sex-selective cognitive deficit following postnatal PBDE-209 exposure in mice
Authors: Gupta Priya , Gupta Rajaneesh K. , Gandhi Behrose S. , Singh Poonam 
Published: August 2022

Abstract
Neonatal exposure to decabromodiphenyl ether (PBDE-209), a ubiquitous environmental pollutant, affects cognitive performances in the later stage of life in a sex-dependent manner. PBDE-209 interferes with glutamatergic signaling and N-methyl-D-aspartate receptor (NMDAR) subunits with unresolved regulatory mechanisms. This study exposed male and female mice pups through postnatal day (PND) 3–10 to PBDE-209 (oral dose: 0, 6, or 20 mg/kg body weight). The frontal cortex and hippocampus, collected from neonate (PND 11) and young (PND 60) mice, were analyzed for cAMP response element-binding protein (CREB) and RE1-silencing transcription factor/ Neuron-restrictive silencer factor (REST/NRSF) binding to NMDAR1 promoter and expression of NMDAR1 gene by electrophoretic mobility shift assay and semi-quantitative RT-PCR respectively. Behavioral changes were assessed using spontaneous alternation behavior and novel object recognition tests in young mice. In neonates, the binding of CREB was increased, while REST/NRSF was decreased significantly to their cognate NMDAR1 promoter sequences at the high dose of PBDE-209 in both the sexes. This reciprocal pattern of CREB and REST/NRSF interactions correlates with the up-regulation of NMDAR1 expression. Young males followed a similar pattern of CREB and REST/NRSF binding and NMDAR1 expression as in neonates. Surprisingly, young females did not show any alteration when compared to age-matched controls. Also, we found that only young males showed working and recognition memory deficits. These results indicate that early exposure to PBDE-209 interferes with CREB- and REST/NRSF-dependent regulation of the NMDAR1 gene in an acute setting. However, long-term effects persist only in young males that could be associated with cognitive impairment.
The Role of Systemic Immune Inflammation Index in Predicting Treatment Success in Tuboovarian Abscesses
Authors: kose caner , korpe busra , korkmaz vakkas , ustun yaprak engin 
Published: August 2022

Abstract
Purpose
The aim of this study was to determine the predictability of the systemic immune inflammation index (SII) on the response to medical treatment in tubo-ovarian abscess (TOA).
Methods
296 patients with TOA in a tertiary center were enrolled in the study. Patients were divided into two groups: Group1 (n = 165) included patients in whom medical treatment was successful, and Group2 (n = 131) included patients in whom surgery was required. Demographic, sonographic and laboratory findings were compared between groups. SII was calculated using peripheral blood parameters [SII= (platelets*neutrophils)/lymphocytes].
Results
Age, BMI, gravida, parity, smoking and menopausal status, CRP levels of patients were similar in both groups (p > 0.05). Mass size (4.398 ± 0.306 vs 7.683 ± 0.689, p < 0.001), white blood cell (WBC) (8685.08 ± 3981.98 vs 9994.35 ± 4468.024, p = 0.008), Hb (12.18 ± 1.65 vs 11.68 ± 1.65, p = 0.010), platelet to lymphocyte ratio (PLR) (151.26 ± 74.83 vs 230.77 ± 140.25, p < 0.001), neutrophil to lymphocyte ratio (NLR) (4.21 ± 3.27 vs 6.07 ± 6.6, p = 0.003), monocyte to lymphocyte ratio (MLR) (0.300 ± 0.177 vs 0.346 ± 0.203, p = 0.041) and SII (1014.18 ± 781.71 vs 2094.088 ± 2117.58, p < 0.001) were statistically higher in group 2. ROC Analysis was used to determine the predictability of the variables and PLR (AUC = 0.718, p < 0.001), NLR (AUC = 0.593, p = 0.593), MLR (AUC = 0.576, p = 0.024), SII (AUC = 0.723, p < 0.001) and size of mass (AUC = 0.670, p < 0.001) were found to be significant. The SII, size of mass and bilateral involvement of adnexa were found to be the strongest prognostic factors for surgical intervention (OR:1.004 (1.002–1.005), OR:1.018 (1.010–1.027), OR:3.397 (1.338–8.627); p < 0.001, p < 0.001, p = 0.010 respectively).
Conclusion
SII, size of mass and bilaterality can be used to predict medical treatment success in patients with TOA.
Dietary Choline and Sphingomyelin Choline moiety Intake and Risk of Colorectal Cancer: A Case Control Study
Authors: Rossi Marta , Khalifeh Malak , Fiori Federica , Parpinel Maria , Serraino Diego , Pelucchi Claudio , Negri Eva , Giacosa Attilio , Crispo Anna , Collatuzzo Giulia , Hannun Yusuf , Luberto Chiara , Vecchia Carlo La , Boffetta Paolo 
Published: August 2022

Abstract
Introduction: Phospholipids are possible favorable agents for colorectal cancer (CRC). Choline has been inversely related to CRC risk but findings are inconsistent. Our study aimed to assess the effect of dietary sphingomyelin (SM) choline moiety and total choline on risk of CRC.Method: This analysis is based on a multicenter case–control study conducted between 1992 and 1996 in Italy. A total of 6107 subjects were enrolled, including 1225 colon cancer cases, 728 rectal cancer cases and 4154 hospital-based controls. We applied data on the composition of foods in terms of SM choline moiety and choline intake on dietary information collected through a validated food-frequency questionnaire. Odds ratio (OR) for energy-adjusted tertiles of SM choline moiety and choline were estimated through logistic regression models adjusted for sex, age, center, education, alcohol consumption, body mass index, family history of CRC, and physical activity.Results: Choline was inversely related to CRC risk (OR=0.85, 95% confidence interval [CI] 0.73-0.99). This association was consistent in colon and rectal cancer. SM choline moiety was not associated with CRC risk (OR=0.96, 95% CI 0.84-1.11).Conclusion: This study shows an inverse association between choline intake and CRC, while no association was found with SM choline moiety.
Increasing Muscle Hypertrophy with a Natural Product Designed to Inhibit SIRT1
Authors: Pathak Suraj J. , Wallace Marita , Athalye Sonia , Schenk Simon , Langer Henning T. , Baar Keith 
Published: August 2022

Abstract
We have previously identified a series of molecular brakes that slow muscle growth. One potential molecular brake is SIRT1, which is activated by a negative caloric balance. In this work, we identified natural product inhibitors of SIRT1 and tested their effects on load-induced increases in muscle fiber cross-sectional area (fCSA) using an incomplete factorial design. Supplying varying amounts of three natural products during two-week overload resulted in increases in fCSA that varied from − 2 to 113%. Using these data, we produced a model that predicted the optimal combination and concentration of each natural product and validated this model in a separate cohort of animals. Following two-week overload, fCSA in the optimal group increased 62%, whereas in the placebo fCSA increased only 3%. The greater increase in fCSA was associated with decreased ribosomal RNA synthesis, and a trend for decreased total RNA. Despite the lower ribosome biogenesis, the increase in protein synthesis was similar, suggesting that the natural product cocktail may be increasing ribosomal efficiency rather than capacity. These data suggest that inhibition of SIRT1, together with exercise, may be useful in increasing muscle fCSA.
Assessment of some physical, chemical and biological parameters of Lake Dangana, Nigeria
Authors: Adamu K. M. , Mohammed Y. M. , Ibrahim U.F , Abdullahi I.L , Jimoh Y.O 
Published: August 2022

Abstract
In maintaining health aquatic ecosystem, there is the need to have a balance biotic and abiotic factors thus this study was conducted to assess some physical, chemical and biological parameter of Lake Dangana in Lapai, Niger State for period of eight (8) month (January-August, 2020) in identified sample stations using standard protocols and procedures. The result revealed mean Temperature (23.5-26.5ºC), Dissolved oxygen concentration (3.96-4.13mg/l), Biochemical Oxygen Demand (3.00-3.12mg/l), pH value (6.88-7.11), conductivity (86.43-94.80µS/cm), nitrate (0.67-0.76mg/l) and phosphate (0.85-1.04mg/l). There was no significant difference (p>0.05) in the monitored Water temperature, Dissolved Oxygen, Biochemical oxygen Demand and pH between sampling station. However, electrical conductivity, nitrate and phosphate differs significantly (p<0.05) among sampling stations. Similarly, significant difference (p<0.05) was noticed among sampling months in all the physicochemical parameters measured. A total of 318 individuals from 13 species and 10 families of macroinvertebrates were encountered during the study period. Percentage occurrence revealed; Hemiptera (35.52%), Coleopterans (34.59%), Odonata (22.95%), dipterans (5.03%) and Oligochaetes (1.87%). The canonical correspondence analysis (CCA) ordination plot showed a good relationship between measured physicochemical parameters and macroinvertebrates distribution and composition. Six (6) species of bacteria were isolated, four Gram positive bacteria and two (2) Gram negative bacteria. The Gram-positive bacteria were Bacillus sp. Escherichia coli, Micrococcus sp and Staphylococcus aureus. Whilst, the two Gram-negative bacteria were Klebsiella sp and Pseudomonas sp. Five (5) species of fungi were isolated; Aspergillus fumigates, Aspergillus niger, Aspergillus flavus, Penicillium sp and Mucor sp. All the fungi isolates were found in all the sampling stations of the lake. The presence of some of these microorganisms is an indicator of contamination which implies that the water body is contaminated with fecal matter; thus, the pathogenic bacteria and the low water quality constitutes danger to public health.
Liquid level indication and Control system using arduino
Authors: Mohamed Khalifa Dai Elnour 
Published: August 2022

Abstract
Overflow from Liquid tank is a common problem which leads to the wastage of Liquid. Though there are many solutions to it like ball valves which automatically stop the Liquid flow once the tank gets full. So a simple device has been created. This device allow to detect the Liquid level and will raise an alarm upon getting the Liquid tank full or a preset level show the level percentage on LCD, then controlling the process of turn pump on and turn it off operation. Liquid level indicator is a modern way of measuring the liquid level using latest technologies like Arduino as as a programming unit and many different types of sensors like Ultrasonic, LDR,PIR, ……etc. The main aim of the project is to calculate the Liquid level at any instant of time and to turn the pump on when the tank is empty or at specific level and turn it off if the tank is filled completely. As a result of this project the percentage of liquid’s level has shown on a display unit (16*2 Liquid Crystal Display), and the fuel pump has been automatically controlled.