bluuebunny/crossref_metadata_2025_split huggingface dataset:
Haemoglobin and iron store status in low birth weight babies and effect of early iron supplementation on them A randomized and open label study
Authors: Gobbur RH , Umaima AG Safoora , Kalyanshettar SS 
Published: October 2022

Deficiency of iron affects multiple organ systems, and poor neurodevelopment is the most worrisome effect. Low birth weight neonates are more likely to develop iron deficiency anemia than term counterparts. The guidelines for supplementation of iron in LBW neonates are poorly defined with varying recommendations pertaining to the intiation. Hence this study focuses on the effect of early iron supplementation and iron store status in them.In this randomized open label interventional study, 48 LBW neonates (EI group) were administered iron supplementation (at 2 weeks or earlier when full feeds were achieved), and other 48 were controls. All neonates were assessed for hemoglobin level, RBC count and iron status indicators (Hematocrit, Serum Ferritin) at or after 6 weeks of postnatal age. The post-intervention values of mean haemoglobin (cases 12.68±1.51g/dl, Controls – 11.38 ± 1.03g/dl), mean serum ferritin (cases: 238.45 ng/ml, CONTROLS- 175.68 ng/ml), mean RBC count (cases: 3.94 million/mm, and mean hematocrit (cases: 33.16±3.75%, controls 34.04±3.45%)were noted, and the % change at 6 weeks follow up in mean Hb among - 25.19%, 31.45% (0.01); % change in mean ferritin at follow up: cases 15.13%, controls 32.99% (0.001); % change in mean RBC count at follow up: cases 19.21%, 33.82% (0.001)] when compared to pre- inetervention values was noted. Though the haematological parameters decreased in both groups, the levels were comparatively higher in the cases compared to the controls, and iron store status was better in early iron-supplemented infants. Iron supplementation in LBW neonates started as early as 2 weeks postnataly, improves the iron stores and decreases the risk of iron deficiency in these infants.
Knowledge, Attitude, Practice with respect to Epilepsy in final year M.B.B.S. medical students
Authors: Kavthekar Saiprasad Onkareshwar , Patil Mohan Anantrao , Kulkarni Devayani Ajit , S Yamini , Divyasri Nagisetti , Desai Manjiri M. 
Published: October 2022

Epilepsy is a common chronic neurological disorder affecting children as well as adults. It is associated with misconceptions, myths and social stigma. Patient, parents, family members, school teachers, medical professionals look at this disorder with different perspective. Knowledge, Attitude and Practice (KAP) regarding epilepsy has been studied in various segments of population. Not many studies are available in medical students. Also, there are going to be regional variations with respect to KAP regarding epilepsy. Such study is not done in this region. Hence, this study was planned. Descriptive cross-sectional study was under taken in 102 final year M.B.B.S. students. Self-administered questionnaire was used for data collection. 51% students answered correctly in knowledge domain, 69% answered in attitude domain and 58% answered correctly in practice domain. Only 21% students were exposed in management of epilepsy patient. 86-87% students expressed to include epilepsy topic should be included in undergraduate syllabus and need for clinical posting of final year students in emergency department. Final year medical students had better attitude towards epilepsy but had average knowledge and practicesabout epilepsy.
Evaluation of mandibular condylar position in different malocclusion with Gelb’s grid
Authors: Soni Deepa , Khanna Rohit , Tikku Tripti , Maurya Rana Pratap , Verma Sneh Lata , Srivastava Kamna 
Published: October 2022

To assess condylar position using Gelb’s grid in subjects with different malocclusion. Pre- treatment lateral cephalogram of 45 subjects (aged above 18yrs) were taken and equally divided in three groups, Group I(skeletal Class I malocclusion), Group II-(skeletal Class II malocclusion) and Group III (Class III malocclusion) based on three Cephalometric parameters (ANB, Yen angle and Wits appraisal). Condylar position in relation to glenoid fossa was assessed with Gelb’s grid. For Group I condyle was positioned normally (4,7) in 86.66% of subjects and was positioned posteriorly (5,8)13.33% of subjects. For Group II condyle was displaced posteriorly (5,8) in 86.66% of subjects and in normal position (4,7) for remaining subjects. For Group III subjects condyle was again found in posteriorly displaced 66.66% of subjects and normally positioned in rest of subjects. It can be suggested that the condylar position showed variability in three malocclusion groups. Class I malocclusion group with no skeletal discrepancy was associated with more symmetric normal condylar position than malocclusion groups with skeletal discrepancy (Class II and Class III).
Profesor Zbigniew Słupski (1934-2020) – mistrz sinologicznej rzetelności
Authors: Kasarełło Lidia 
Published: October 2022

Autorka wspomina Zbigniewa Słupskiego (ur. 3 czerwca 1934 r. w Ostrawie, zm. 6 sierpnia 2020 r. w Warszawie), polskiego sinologa, profesora doktora habilitowanego, wieloletniego wykładowcy i kierownika Zakładu Sinologii na Wydziale Orientalistycznym Uniwersytetu Warszawskiego, gdzie pracował od 1973 r., uzyskując habilitację i tytuł profesora, chociaż studiował na Uniwersytecie Karola w Pradze, gdzie zrobił w 1965 r. doktorat pod kierunkiem prof. Jaroslava Průška. Profesor Słupski specjalizował sie w literaturoznawstwie, chińskiej literaturze, historii i filozofii. Był autorem prac historyczno- i teoretycznoliterackich, dotyczących zwłaszcza współczesnej literatury chińskiej, w sposób szczególny opowiadań, jak też wczesnego piśmiennictwa chińskiego. Poza tym był tłumaczem rozlicznych historycznych i współczesnych dzieł chińskich, wydawanych m.in. w redagowanych przez siebie antologiach.
An experimental study of Canal Water Purification in Chochocho Bushbuckridge Municipality Mpumalanga Province
Authors: Mafuwane Hluphi Constance , Muchie Mammo 
Published: October 2022

Purpose: The purpose of this research is to evaluate the social, economic, and political feasibilities of providing water purification technologies to rural areas of Bushbuckridge Municipality, specifically Chochocho residents.
Methodology: For this study, the following techniques were used: Questionnaire survey, simple survey, Observation, and group focus. Data was collected by fieldwork visiting the community members drinking polluted water and getting information utilizing calling individuals. Random sampling was done for this study from community members in Chochocho in Mpumalanga to collect data from known and unknown individuals and municipal officials. During the survey, we observed that residents were drinking polluted water.
Main Findings: The study results show that Moringa oleifera powder cleans polluted water quicker and cheaper than paper filters and homemade filters.
Implications of study: The results of this study can serve as a foundation for investors interested in entering the technological market. Therefore, Bushbuckridge municipality needs to develop a business strategy to assist the municipality in approaching water purification markets as a collective and social responsibility in the long term. The findings of this study can help the local municipality and the Department of water and sanitation to provide a water pipeline and erect a water purification plant to supply the community with clean water.
Novelty of the study: The study will demonstrate knowledge and skills to the young generation through research, and residents and the young generation will gain more innovative ways how to treat polluted water in Chochocho and increase the good health and livelihoods of residents in Chochocho in Bushbuckridge Municipality.
Surface Uses in Solar Neighborhoods
Authors: Hachem-Vermette Caroline , Formolli Matteo , Vettorato Daniele 
Published: October 2022

This report has been completed through international collaboration under the International Energy Agency (IEA) Solar Heating and Cooling (SHC) Programme - Task 63 on Solar Neighborhood Planning. Specifically, the work contributes to Task 63 Subtask B - Economic Strategies and Stakeholder Engagement by identifying and discussing the potential usage of different urban surfaces in harvesting solar energy. Special focus has been placed on the identification of conflicts and synergies among solutions, and their contribution to the major climate resilience and sustainability objectives defined by solar neighborhoods.
Greenhouse gas emissions from hydroelectric reservoirs: Mechanistic understanding of influencing factors and future prospect
Authors: Kumar Amit , Kumar Amit , Chaturvedi Ashish K. , Joshi Neeshu , Mondal Raju , Malyan Sandeep K 
Published: October 2022

Abstract

Since the pre-industrial era (1990s), greenhouse gas (GHG) emissions from hydroelectric reservoirs have been a debatable subject of interest due to a substantial contribution to global warming. Rising demand for various renewable and non-renewable energy resources became necessary for rapid economic growth to the exponentially rising population in developing countries. Reducing GHG emissions is the key target of COP-26 for climate change mitigation. However, precise methodologies for quantification of GHG, key parameters affecting emission rate is a challenging task attributed to limited tools, techniques for GHG measurement, uncertainty rate in measurement, insufficient GHG database, and huge spatio-temporal variability of emission in global reservoirs. This work highlights the present scenario of GHG emissions from renewable energy with targeted approach on hydroelectric reservoirs, methodological know-how, interrelation between parameters affecting GHG emission, and mitigation strategies. Apart from this, major tools and techniques to predict GHG emissions from hydroelectric reservoirs, accounting of GHG emissions, life cycle assessment, sources of uncertainty, and knowledge gaps have been discussed in detail.
Critical factors identification of digital innovation in manufacturing enterprises: Three stage hybrid DEMATEL-ISM-MICMAC approach
Authors: Feng Xiangqian , Li Eryang , Li Jian 
Published: October 2022

Abstract
In the era of digital economy, the digital innovation of manufacturing enterprises has become the main trend of development. This paper constructs an effective and reliable hierarchical framework for identifying critical factors of digital innovation in manufacturing enterprises based on the three stage hybrid DEMATEL-ISM-MICMAC method. Through literature reading and expert judgment, this paper determines the 19 factors that affect the digital innovation of manufacturing enterprises. The DEMATEL technique is used to establish the causal relationship between the factors, the ISM technique is used to stratify the factors, and the MICMAC technique is used to divide the types of influencing factors according to the driving force and dependence, and analyze the correlation between each level and its influence on the digital innovation of manufacturing enterprises. The results show that social capital, learning organization, digital technology, and knowledge are the most important influencing factors in the process of digital innovation in manufacturing enterprises. In particular, the two key factors of social capital and learning organization should be paid attention to by manufacturing enterprises. This research can help the managers of manufacturing enterprises to find out the key influencing factors of the digital innovation of manufacturing enterprises, and give targeted suggestions to promote the process of enterprise digitalization.
A new photocatalyst: triple heterojunction Yb3+-Bi2O3/BiOIO3 catalyst for mercury removal from flue gas
Authors: Ren Siyuan , Li Tong , Wu Jiang , Zhou Min , Peng Cheng , Zhang Hai , He Ping , Qi Xuemei , Song Mao , Zhou Yuzhuo , Chen Shuo 
Published: October 2022

Abstract
The Yb3+-Bi2O3/BiOIO3 triple heterojunction photocatalyst was successfully prepared by the EG assisted hydrothermal method and the calcination method. Bi2O3 has a variety of crystal phase structures. Through characterizations and DFT theoretical calculations, it is shown that different proportion of Yb3+ doping makes the lattice phase transition of Bi2O3. When the mole ratio of Yb3+ doping in the complex is 1%, the coexistence and recombination of α-Bi2O3, β-Bi2O3 and BiOIO3 lead to the formation of triple heterojunction and the establishment of a unique electronic transmission channel, which promote the separation of photogenerated carriers. At the same time, Yb3+ ions have unique electronic transition characteristics, which effectively broaden the spectral response range of the Yb3+-Bi2O3/BiOIO3 photocatalyst, and also improve the photocatalytic activity. Thanks to its optimized performance, the best efficiency of the Yb3+-Bi2O3/BiOIO3 triple heterojunction photocatalyst in removing gaseous Hg0 under visible light can reach 76.73%, which is much higher than that of its pure component. Finally, the mechanism of high efficiency catalytic oxidation was proposed by combining rare earth ion doping with semiconductor recombination to construct heterojunction catalysts with a wide spectral response. This work provides a new method for designing efficient photocatalysts.
Robust chaos and multi-stability in piecewise linear recurrent neural networks
Authors: Monfared Zahra , Patra Mahashweta , Durstewitz Daniel 
Published: October 2022

Abstract
Recurrent neural networks (RNNs) are major machine learning tools for the processing of sequential data. Piecewise-linear RNNs (PLRNNs) in particular, which are formally piecewise linear (PWL) maps, have become popular recently as data-driven techniques for dynamical systems reconstructions from time-series observations. For a better understanding of the training process, performance, and behavior of trained PLRNNs, more thorough theoretical analysis is highly needed. Especially the presence of chaos strongly affects RNN training and expressivity. Here we show the existence of robust chaos in 2d PLRNNs. To this end, necessary and sufficient conditions for the occurrence of homoclinic intersections are derived by analyzing the interplay between stable and unstable manifolds of 2d PWL maps. Our analysis focuses on general PWL maps, like PLRNNs, since normal form PWL maps lack important characteristics that can occur in PLRNNs. We also explore some bifurcations and multi-stability involving chaos, since the co-existence of chaotic attractors with other attractor objects poses particular challenges for PLRNN training on the one hand, yet may endow trained PLRNNs with important computational properties on the other. Numerical simulations are performed to verify our results and are demonstrated to be in good agreement with the theoretical derivations. We discuss the implications of our results for PLRNN training, performance on machine learning tasks, and scientific applications.
Mathematics Subject Classification (2020) 37F46 · 34H10
Pharmacokinetic study of Yindan Xinnaotong soft capsule after oral administration in rats and its network pharmacology-based analysis on cardiovascular diseases
Authors: Li Jun-Ming , Huang An-Xian , Yang Liu , Gao Wen 
Published: October 2022

Abstract
Background
Yindan Xinnaotong soft capsule (YDXNT) is a Chinese herbal preparation, which was used to treat coronary disease, angina, hyperlipidemia and stroke in the clinic. The chemical ingredients of YDXNT have been investigated, but the pharmacokinetic study of the absorbed components of YDXNT and the exploration of their effect on cardiovascular diseases (CVD) are still insufficient.
Method
A sensitive and accurate quantitative method based on ultra-high performance liquid chromatography tandem triple quadrupole mass spectrometry (UHPLC-QQQ MS) was established and validated, which was then applied to the pharmacokinetic study of the potential active compounds in the plasma of rats after oral administration of YDXNT. Then the measured analytes were regarded as effective compounds and their potential targets and mechanism of action were predicted after the construction and analysis of compound-target network of YDXNT and CVD.
Results
The UHPLC-MS based quantitative method was verified to have acceptable linearity, specificity, accuracy, precision, matrix effect, extract recovery and stability for pharmacokinetic analysis, and 15 absorbed compounds in rat plasma after oral administration of YDXNT was studied. Different types of compounds showed various pharmacokinetic characteristics, for instance, ginkgolides with higher maximum plasma concentration (Cmax), flavonoid presenting concentration-time curve with double peaks, phenolic acids with shorter time to reach maximum plasma concentration (Tmax), saponins with long elimination half-life (t1/2) and tanshinones showing fluctuant plasma concentration. Then a network pharmacology-based analysis indicated that those potential active compounds of YDXNT interacted with targets such as MAPK1 and MAPK8, and intervened in the MAPK signaling pathway to display its therapeutic effect on CVD.
Conclusion
The pharmacokinetics combined network pharmacological analysis provides the potential pharmacological compounds and their integrating mechanism of YDNXT against CVD.
Multi Level Bank Locker Security System with Digital Signature Authentication and Internet of Things
Authors: Islam Md. Ashiqul , Sarder Md. Sumon , Mamun Mehedi Hasan , Ahmed Faruq , Sarkar Sujit Kumar , Mridul Aunik Hasan , Ahmed Md. Tanvir , Khatun Tania 
Published: October 2022

Abstract
Recently bank security is being a matter of great awareness and importance in the world. Though, we designed a multi-layer Bank security system to preserve the bank locker from stealing and unauthorized access. A multi-layer bank locker security system can be legalized, and monitored and prevent security in a bank locker room or unauthorized access. This security system is a highly reliable multi-level security system to protect lockers. This banking security system with a high-security two-door system, multi-layer wall based on infrared radiation and GSM technology, sensors such as sound sensor, motion sensor, laser sensor, gas sensor, IP camera, microcontroller keyboard, LCD monitor, etc. There is a biometric system, such as an iris scanner with a fingerprint scanner and a unique RFID card that protects the main door of the locker room and infrared rays pass from the infrared radiation source into the parallel section of the wall to prevent any accidents such as wall breaks. SMS are sent to the officials if the camera is detected any unauthorized motion and the alarm is on to warn the officials. People are accessing their bank lockers in the waiting room, and robotic arms are searching their lockers where they can sign the digital signature, enter the PIN and locker number in the second door keypad and they can access their locker using a message authentication system and locker key. After accessing the locker they can click the exit button and the robotic arms put the locker in the right place. This multi-level security system is more secure to protect the bank locker and safe transactions.
Protomer Selectivity of RAF Inhibitors Within the RAS/RAF Signalosome
Authors: Vasta James , Michaud Ani , Zimprich Chad , Thomas Morgan , Wilkinson Jennifer , Crapster J. Aaron , Robers Matthew 
Published: October 2022

Abstract
RAF dimer inhibitors offer therapeutic potential in RAF- and RAS-driven cancers. The utility of such drugs is predicated on their capacity to occupy both RAF protomers in the RAS-RAF signaling complex. Here we describe a method to conditionally quantify drug-target occupancy at selected RAF protomers within an active RAS-RAF signalosome in cells. RAF target engagement can be measured in the presence or absence of any mutant KRAS allele, enabling the high affinity state of RAF dimer inhibitors to be quantified in the cellular milieu. The intracellular selectivity of clinical-stage drugs for individual protomers within BRAF, CRAF, and ARAF heterodimers in complex with mutant KRAS-GTP revealed that ARAF protomer-engagement, but not engagement of BRAF or CRAF is commensurate with inhibition of MAPK signaling in various mutant RAS cell lines. Our results support a fundamental role for ARAF in mutant RAS signaling and highlight the avoidance of ARAF protomers for a cohort of RAF inhibitors undergoing clinical evaluation.
Female calling and copulation behaviour of Indian population of an invasive pest, Spodoptera frugiperda (J. E. Smith, 1797)
Authors: Ramya Nagaraju , Sagar Doddachowdappa , Kumar Padala Vinod , Rupali Jagadam Sai , Kumar Hemant , Reshma Ramankutty , Yadav Priya , Seth Rakesh Kumar 
Published: October 2022

Abstract
An experiment was conducted to study and document the copulation duration and effect of mating on female calling behaviour of Indian population of an invasive pest, Spodoptera frugiperda (J. E. Smith). Results showed that 58.39% of the females in absence of males and 88.18% of females in presence of males exhibited calling on first scotophase and onset time of calling was early in females in presence of males. Calling length and calling bouts varied significantly with increase in age in virgin females, while in multiple mated females it showed declining trend. The copulation duration of S. frugiperda varied between 78.00±7.35 min to 197.14±11.06 min with maximum copulation duration and percentage of females mated was observed on second scotophase. The fecundity of multiple mated females ranged between 841 to 1849 with mean of 1176±113 while in single mated females it ranged between 476 to 1368 with mean of 878±175. Practically our results indicated that the calling and mating takes place on first scotophase and it was on peak in second scotophase. This information can be used in formulating biorational molecules, which may modulate calling behaviour and improve mating disruption in S. frugiperda for its management.
Prognostic and Immunological Role of RBMX in cancers
Authors: Sheng Yilei , Tu Zewei , Sun Chengpeng , Long Xiaoyan , Wu Lei , Huang Kai , Zhu Xingen 
Published: October 2022

Abstract
Cancer, as the disease causing the highest morbidity and mortality worldwide, attracted all kinds of research investment but received little effect. RBMX, a nuclear RNA binding protein, verified to associated with certain types of cancer through participating in integration of sister chromatids and combination of ribonucleoprotein complex. However, the specific role of RBMX in pan-cancer remains unknown. This article presents the robust role of RBMX in predicting the immunotherapy response and screening the effective prognostic biomarker for cancer therapy. Here, we did comprehensive of RBMX using the sample from the Genotype-Tissue Expression (GTEx) datasets and TCGA pan-cancer cohort. We present experimentally that RBMX’s independent role in prediction and diagnosis. In the future, RBMX blocking-up may become a novel method in cancer therapy.