bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Informasi Pengenalan dan Pendaftaran Santri Berbasis Website pada LKP Tar-Q Padang
Authors: Hayati Nova 
Published: December 2022

Sistem yang telah dijalankan pada LKP Tar-Q Padang masih menggunakan proses manual dalam pendaftaran dan pengelolaan data yang masih belum rapi. Sehingga memepersulit dalam proses penyimpanan data serta arsip santri dan pengajar secara keseluruhan. Untuk proses pembuatan laporan pendaftaran santri baru membutuhkan waktu yang lama dengan menggunakan data manual. Dengan hal itu website LKP Tar-Q Padang ini bertujuan untuk membantu dan memudahkan LKP Tar-Q dalam proses pengenalan dan pendaftaran serta proses seleksi dan pengolahan data santri dan pengajar di LKP Tar-Q Padang. Metode yang digunakan dalam proses seleksi yaitu SAW ( Simple Addtive Weight ). Alat bantu perancangan yang digunakan untuk pembuatan sistem ini adalah UML (Unified Modeling Language), dengan menggunakan software astah, bahasa pemrograman yang digunakan yaitu PHP serta database MySQL dan dengan server Mowes portable II. Berdasarkan uraian di atas, akan dirancang sebuah sistem berbabis website untuk pengenalan dan pendaftaran serta seleksi pada LKP Tar-Q Padang sehingga dapat mempermudah LKP dalam proses kinerja.
Satisfaction level of anti-DM medicine in DM patients in primary health service in Yogyakarta
Authors: Mahanggoro Tri Pitara , Akrom Akrom , Wahyuni Titis Indri 
Published: December 2022

Introduction: Satisfaction with anti-DM drug therapy can affect the effectiveness of and adherence to treatment in diabetic patients. This study aims to determine the description of satisfaction with anti-DM drug therapy for type 2 D.M. patients in primary care.Method: The design of this study was a cross-sectional study of D.M. Patients. We included 109 DM Patients Participants. Data is collected from a perspective and carried out by face-to-face interviews using a questionnaire. We used the Therapy satisfaction questionnaire Medicine (TSQM) for assessing satisfaction with anti-DM drug therapy. We performed uni- and bivariate data analysis using the free-to-play version of SPSS. Characteristic of subject and TSQM scores were presented descriptively.Result: The results of calculations with the help of SPSS version 25 are TSQM mean effectiveness domain 61.583 ± 11.598, side effects domain 54.011 ± 32.340, comfort domain 66.883 ± 8.805, global satisfaction domain 55.715 ± 11.274. Based on the research data, it is known that the level of global satisfaction therapy of D.M. patients in primary health facilities is sufficient. The lowest therapeutic domain of satisfaction is the domain of side effects, and the highest domain is the domain of satisfaction with comfort in drug therapy.Conclusion: The level of D.M. patient satisfaction with anti-DM drug therapy is sufficient. Patients need to be educated about the possible emergence of side effects due to drug use.
Seroprevalence SARS-CoV-2 among the academic population of Universitas Gadjah Mada Yogyakarta
Authors: Sianipar Osman , Intansari Umi Solekhah , Ratnaningsih Tri , Wahyuningsih Arum Tri , Anshori Fuad , Dwiputro Alfin Harjuno , Arjana Adika Zhulhi 
Published: December 2022

Background: Many academicians in Yogyakarta, Indonesia, face the increased potential for Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) transmission in academic populations. Seroprevalence data can represent the number of infections showing the proportion of people exposed and those potentially immune to the virus and provide evidence for public health policymakers. The seroprevalence of SARS-CoV-2 in the academic population of Universitas Gadjah Mada (UGM) remains unknown, raising concerns about the immune status among the academic population. A cross-sectional study was conducted to estimate the seroprevalence rate of SARS-COV-2 infection in the UGM academic population.
Methods: We conducted a descriptive study of 406 subjects of the UGM academic population. In the cross-sectional analysis of data collected, we performed serological testing for SARS-COV-2 infection for random academicians willing to participate voluntarily. Subjects were categorized as high and low-risk based on SARS-CoV-2 exposure and work history. Data normality was tested with Kolmogorov-Smirnov test. Proportion differences were analyzed with chi-squared tests with a significance set as P<0.05.
Result: 406 subjects were included in this study, with most of the subjects (55.91%) being female. The majority of the subjects were students (82.27%). Most of the subjects were categorized as high-risk (51.72%). Eight subjects (1.97%) had reactive antibody testing. The prevalence of SARS-COV-2 infection was higher in the high-risk group than in the low-risk group (3.57% vs. 0.48%; p=0.01). The high-risk subjects had 7.5 times more incidence of reactive antibody results than low-risk subjects based on the prevalence ratio.
Conclusion: The seroprevalence of SARS-COV-2 immunity in the general academic population of the Universitas Gadjah Mada is 1.97%. These low proportions reflect that more strategies are needed to protect the high-risk group against SARS-CoV-2 exposure.
The relationship of tumor necrosis factor alpha levels and neutrophils with skin wound age caused by sharp trauma
Authors: Cangara M. Husni , Sari Indah Wulan , Nelwan Berti Julian , Kaelan Cahyono , Arsyadi Gunawan 
Published: December 2022

Background: Sharp force injuries are the second most common cause of trauma after blunt force injury. TNF- α is a cytokine that triggers the expression of adhesion molecules, other cytokines and chemokines by endothelial cells, stopped and migrated to damaged tissues or infections that trigger inflammation. Furthermore, the initial population of leukocytes leading to the wound comprises mostly neutrophils. This study aimed to assess the correlation between TNF-α levels in the blood and skin tissues and neutrophils number with the wound age of wounds caused by sharp trauma.
Methods: This study is an experimental study using animal models. The samples were divided into the control group and the group in which the blood and the skin tissue samples were taken 1-, 3-, 12-, 24-, 48- and 72 hours after being sharp traumatized. The Elisa method examined the samples from the blood, and the skin of the right back of the mice was examined for TNF-α levels. Others from the left-back skin of the mice were microscopically examined to assess the number of neutrophils.
Results: The TNF- α level from the skin samples were detected in wound tissue as the peak levels were in the 24 hours post-traumatic group. The TNF-α levels from blood samples indicated a significant difference in TNF-α levels in each group (p < 0.05). However, TNF-α levels from skin samples showed no significant difference between each group. From the microscopic examination, there was a significant difference in the infiltration of neutrophil cells in all groups (p<0,05). The neutrophils peak at 24 hours post-traumatic.
Conclusion: There was no significant correlation between the TNF-α levels and the number of neutrophils with the wound age in wounds caused by sharp traumas.
Predictive factors and the relationship between the early detection of osteoporosis and pathological fractures in Indonesian menopausal women
Authors: Supriyatiningsih  , Meiky Fredianto  , Muhammad Arifuddin  , Amalia Rizki Hanif  , Salwa Nabilah Cholfa  , Sulistiari Retnowati  , Ima Rismawati  
Published: December 2022

Background: Estrogen deficiency in menopausal women induces bone loss and makes them prone to pathological fractures. Age, body mass index (BMI), parental history of osteoporosis, and smoking tobacco also increase bone loss and pathological fractures. This study aims to determine whether age, BMI, parental history of osteoporosis, and smoking tobacco can predict pathological fractures in menopausal women. Moreover, the relationship between the early detection of osteoporosis with pathological fracture incidence will also be determined.
Methods: This is an analytic observational epidemiological research with a cross-sectional retrospective design that involved 40 menopausal women. The data were collected from the patients' medical records 2020 in Obstetrics and Gynecology Clinic, Asri Medical Center (AMC) Muhammadiyah Hospital, Yogyakarta. The predictive factors for pathological fracture (age, BMI, parental history, smoking tobacco) were analyzed by using Fisher's exact test and the relationship between osteoporosis early detection, including bone mineral density (BMD) value, parathyroid hormone (PTH) levels, osteocalcin levels, and osteoporosis self-assessment tool for Asians (OSTA) score, with pathological fractures were investigated by using the chi-square test.
Result: Age has a significant relationship with the occurrence of pathological fractures in menopausal women (OR = 6.6, 95% CI: 1.128-8.604, p = 0.042), while BMI, parental history of osteoporosis, and smoking tobacco did not have a significant relationship with pathological fractures (p > 0.05). Early detection of BMD and PTH was also found to have a significant relationship to fracture incidence. Additionally, menopausal women with high PTH levels and osteoporosis BMD values are eight times and four times greater risk of acquiring fractures than menopausal women with normal BMD values and PTH levels.
Conclusion: Age can be a predictive factor for pathological fractures, and the early detection of PTH and BMD is related to the occurrence of pathological fractures in menopausal women.
Do social and environmental factors affect level of stress during COVID-19 among nursing students? Results from single center cross-sectional study in Malaysia
Authors: Sa’at Siti Fatimah , Gill Annabelle Dimple Kharisha , Damianus Bernard Jordan , Saibun Jeremy Dominic , Ukim Gill Lerrkey , Bin Sidek Ahmad Zulkhairul Naim 
Published: December 2022

Introduction: Stress in nursing students has been documented in many studies and this will lead to various health problems. However, there is scanty research assessing the level of stress among nursing students during Covid-19 in Malaysia. Hence, this study aimed to assess the level of stress and its association with social and environmental factors amongst nursing students in Universiti Malaysia Sabah, Malaysia.
Methods: A cross-sectional study was conducted by random sampling among nursing students in Universiti Malaysia Sabah between March and May 2021. The primary outcome was stress symptoms, derived from the validated Perceived Stress Scale-10 (PSS) questionnaire. Socio-demographic, social, and environmental factors were also assessed. T-test was used to assess the associations between level of stress and social and environmental factors.
Results: A total of 115 responses were received with the mean (SD) age of the students being 20.5 (1.3) years old. Of all the students, 84.9% were female, 54.6% received financial support from National Higher Education Fund Corporation and 46.2% were in nursing Year 2 followed by the nursing year 1 (28.6%) and nursing year 3 (25.2%). The students in this study reported a higher level of stress. The students who reported most or all the time being trapped in a hostel (p<0.01), challenges of online classes (p=0.03), and catching up with class projects (p=0.03) had a higher level of stress compared to those who reported none or little or some of the factors.
Conclusion: This study showed that social and environmental factors may play a role in determining the stress level among nursing students. Hence, authorities should foster supporting strategies to lower student stress and tackles the unwanted consequences.
Nomophobia: A new disease epidemic among students during the era of online learning
Authors: Sulistiyani Endang , Tyas Sasmi Hidayatul Yulianing , Novanuari Muhamad , Dwisapta Muhammad Rizqi 
Published: December 2022

Introduction: The Covid-19 pandemic has brought changes to the education system, one of which is the implementation of online learning. This condition makes students like students have to use digital devices, even with a more intense frequency. Therefore, this study aims to determine the level of nomophobia in students as participants in online learning.
Methods: This research is descriptive research with a quantitative approach. The study was conducted with a one-time survey (cross-sectional survey). The research was conducted through 3 stages: preparation of the nomophobia measurement instrument, data collection, and measurement of the level of nomophobia.
Results: 287 respondents were obtained, then the demographics of the respondents can be grouped by gender, age, internet fund source, and online learning media used. Most of the respondents were female (71%) and teenagers (12-25 years) (99%). In addition, the results show that nomophobia has become a new disease epidemic among students, especially in online learning, that requires an increase in the frequency of smartphone access. There are no respondents who are not nomophobia. The respondents have mild nomophobia (6%), moderate nomophobia (40%), and severe nomophobia (54%).
Conclusions: Most of the respondents had a severe level of nomophobia. In addition, the students feel uncomfortable when communicating and accessing information via smartphones or other gadgets, lose connectivity, and cannot use smartphones as desired. Their lives are very dependent on smartphones or other devices. One of the triggers is online learning, where all processes are carried out through digital media. At least students who are not nomophobia also show that nomophobia has proven to be one of the negative impacts that students have to face as participants in online learning.
Correlation between Polymorphisms Interleukin-1 Receptor Antagonist (IL-1RA) And Melasma Severity: A Study of Javanese Female Population in Yogyakarta
Authors: Ekawati Suryanigsih Betty , Sadewa Ahmad Hamim , Wirohadidjojo Yohanes Widodo , Soebono Hardyanto 
Published: December 2022

Background: IL-1 is postulated as a cytokine that plays a fundamental role in the pathophysiology of several skin disorders or diseases. Melasma is a form of hyperpigmentation with a symmetrically distributed predilection for facial features. Due to its elusive pathogenesis, it is believed that the inflammatory factor plays a role in melasma. Increased or decreased IL-1RA concentrations may correlate with the severity of melasma. Therefore, this study aimed to examine the correlation between the IL-1RA (86bp VNTR) polymorphisms and the severity of melasma among a Javanese female population.
Methods: The study involved 79 individuals with melasma and used a cross-sectional design. The severity of melasma was assessed using the MASI (Melasma Area and Severity Index). The data were analyzed using a Chi-square test and Odds Ratio (OR). The genomic DNA from the patients' blood was examined and analyzed using the polymerase chain reaction (PCR) method.
Results: There was an increase in the frequency of IL-1Ra*1/1(410/410) genotype in melasma with a mild severity and of IL-1Ra*1/2(410/240) genotype in melasma with moderate severity (OR: 0.74, 95%CI: 0.26- 2.13, p: 0.42). The allele frequency of IL-1Ra*1/1 was 55.70% at a mild degree and 44.30% at a moderate degree (OR: 0.29-2.11, p: 0.65).
Conclusions: There was no correlation between IL-1Ra VNTR and the severity of melasma; however, it was found that the IL-1Ra*1/1(410/410) genotype and allele frequency tended to be higher in mild melasma, although it was statistically insignificant.
The association between oral antibiotics with the decreased severity index of acne vulgaris in the medical cosmetics division dermatovenereology outpatient clinic of Dr. Soetomo General Teaching Hospital Surabaya from 2017- 2019
Authors: Farah Meriana Fajrin  , Citra Dwi Harningtyas  , Rahmadewi  , Afif Nurul Hidayati  , Sawitri  , Diah Mira Indramaya  , Rebekah Juniati Setiabudi  , Muhammad Yulianto Listiawan  
Published: December 2022

Background: Acne vulgaris (AV) is a chronic inflammatory disease of the pilosebaceous unit. AV therapy is given based on the severity of AV. Oral antibiotic therapy is routinely prescribed to treat moderate to severe inflammatory acne. The purpose of this study is to determine the relationship between systemic antibiotic administration and the decrease in the severity of acne vulgaris.
Methods: This was a retrospective study with an analytical design, carried out on 49 medical records that met the inclusion criteria for acceptance of the sample; new AV patients come with grades 2, 3, and 4 to the Medical Cosmetics division Dermatovenereology Outpatient Clinic of Dr. Soetomo General Teaching Hospital Surabaya in the period January 2017 - December 2019.
Results: This study was conducted on 49 patients with acne vulgaris grade 2,3,4 who came to follow-up in a week 2,4,8 treatment. Data from the first follow-up group, 26 subjects (53.1%) experienced a decrease in grade; from the second follow-up group, 25 subjects (51.0%) experienced a decrease in grade; from the third follow-up group, 38 subjects (77, 6%) experienced a decrease in the group comparing with condition patient before treatment. Analytic comparative showed that the condition of the first visit compared to the first, second and third follow-up groups were 0,180, 0,000, and 0,000, respectively. The significance test results showed a value of 0.000 (p ≤ 0.05) in the second and third follow-up groups, which is statistically significant.
Conclusion: An oral antibiotic can effectively reduce the severity degree of acne vulgaris in four to eight weeks after treatment with an oral antibiotic.
Correlation between clinicopathological factors and clinical outcomes of recurrent epithelial ovarian cancer at a tertiary hospital in Surabaya, Indonesia
Authors: Prabowo Adityo , Tjokroprawiro Brahmana Askandar , Utomo Budi 
Published: December 2022

Introduction: Ovarian cancer is one of the leading causes of cancer death in women globally. The objective of this study was to determine the correlation and the association between age, stage, histopathology, grade, ascites, tumor residual, CA-125 level, and type of surgery on recurrence, disease-free survival, overall survival and mortality of epithelial ovarian cancer patients.
Methods: An analytical retrospective study using medical records and interviews of epithelial ovarian cancer patients was conducted in Dr. Soetomo Hospital. The study included the data from January 2016-December 2020. Kaplan-Meier and log-rank test were used to assess the factors associated with disease-free survival (DFS) and overall survival (OS).
Results: A total of 358 patients with epithelial ovarian cancer from 2016 to 2020 were included in the study of which 153 of recurrence cases. Clinicopathological factors that correlated with disease-free survival were stage, histopathology, grade, ascites, tumor residual, CA-125, and type of surgery (p<0.05). The factors that correlated with overall survival were stage, histopathology, grade, ascites, residual tumor, and CA-125 value (p<0.05). The most significant factors associated with recurrence and mortality were stage, grade, and ascites. Stage II and III had an HR (hazard ratio) of 1.9 and 2.1 for recurrence compared to stage I, respectively. Grade II and III patients had HRs of 2.1, and 3.4 for recurrence compared to stage I, respectively. The presence of ascites had an HR of 1.5 compared to those had no ascites. Stage III had an HR of 1.9 for mortality compared to stage I, respectively. Grade II and III patients had HRs of 3.6, and 5.0 for death compared to stage I, respectively. The presence of ascites had an HR of 1.6 compared to patients with no ascites. Compared to serous type, those patients with mucinous and clear cell had HR of 1.8 and 3.1 for mortality, respectively
Conclusion: Stage, grade, and ascites were the most significant factors in the incidence of recurrence and mortality of epithelial ovarian cancer.
Overview of transfusion reactions in patients with incompatible crossmatch at Sanglah General Hospital, Denpasar, Bali, Indonesia
Authors: Betti Bettavia Hartama Pardosi  , Ni Kadek Mulyantari  , Ida Ayu Putri Wirawati  , Anak Agung Wiradewi Lestari  , Ni Nyoman Mahartini  
Published: December 2022

Background: Transfusion reaction is a side effect of giving complete blood or one of the components. They vary in severity, ranging from reactions that can occur during a transfusion (acute transfusion reactions) or reactions occurring days to weeks later (delayed transfusion reactions) and can be immunological and non-immunological. This study investigated the description of transfusion reactions in patients who received blood with incompatible crossmatch results at Sanglah General Hospital
Methods: This research is a descriptive study with a cross-sectional approach. Several parameters were assessed in this study to determine the transfusion reaction in patients who receive blood with incompatible crossmatch. Data were analyzed using SPSS version 20 for Windows.
Results: In this study, from 72 patients who received incompatible blood, 75.0% were found for women and 25.0% for male patients, most of whom were aged 41-65 years (65.0%). Most blood type is blood type O (52.0%). In this study, 6 patients (8.3%) got transfusion reactions such as fever accompanied by chills, urticaria, hypotension, and shortness of breath.
Conclusions: Incompatible crossmatch blood administration can be given. If a reaction is given to a crossmatch transfusion that is not suitable, symptomatic therapy can be given because the response provided is only acute and mild.
Characteristics of patients with acute lymphoblastic leukemia in 2016-2020 at Sanglah General Hospital, Bali
Authors: Evelin Vianetha Prima Snak  , Ni Nyoman Mahartini  , Sianny Herawati  , Ni Kadek Mulyantari  , Anak Agung Wiradewi Lestari  
Published: December 2022

Background: Acute lymphoblastic leukemia (ALL) is a bone marrow malignancy that is the most common cause of death in children. This study aims to determine the characteristics of ALL patients in 2016-2020 at Sanglah Hospital Denpasar, Bali.
Methods: This study used a retrospective descriptive study with secondary data from 166 patients. Variables assessed in this study included: demographic characteristics (age, gender, place of origin), complete blood count results include of hemoglobin levels, leukocyte (white blood cell) count, absolute neutrophil count, absolute lymphocyte count, thrombocyte count, and morphology subtype of ALL based on FAB classification from bone marrow aspiration (BMA).
Results: From demographic characteristics: most patients' age was in school-age children (>6 - <18 years) about 59.7%, dominated by male (60.2%), place of origin from Bali (71.7%) which is from Denpasar city (23.5%). From the laboratory results, complete blood count found that the most results are moderate anemia in children (54.7%), in adult female (70%), and in adult male (52.9%); leukocytosis in children (41%), in adult (77.8%); neutropenia in children (61.2%), in adult (59.3%); lymphocytosis in children (43.2%), in adult (81.5%); thrombocytopenia in children (97.1%), in adult (100%). From the results of the BMA examination, based on the FAB (French, American, and British) classification, the most common morphology of ALL was L2 subtype (78.9%).
Conclusion: Characteristics of patients with ALL at Sanglah General Hospital are dominated by children, male, from Denpasar, Bali, with laboratory results showing moderate anemia, leukocytosis, neutropenia, lymphocytosis, thrombocytopenia, and the most common morphological variants are ALL-L2 subtype.