bluuebunny/crossref_metadata_2025_split huggingface dataset:
Specificity ratings for Italian data
Authors: Bolognesi Marianna Marcella , Caselli Tommaso 
Published: September 2022

AbstractAbstraction enables us to categorize experience, learn new information, and form judgments. Language arguably plays a crucial role in abstraction, providing us with words that vary in specificity (e.g., highly generic: tool vs. highly specific: muffler). Yet, human-generated ratings of word specificity are virtually absent. We hereby present a dataset of specificity ratings collected from Italian native speakers on a set of around 1K Italian words, using the Best-Worst Scaling method. Through a series of correlation studies, we show that human-generated specificity ratings have low correlation coefficients with specificity metrics extracted automatically from WordNet, suggesting that WordNet does not reflect the hierarchical relations of category inclusion present in the speakers’ minds. Moreover, our ratings show low correlations with concreteness ratings, suggesting that the variables Specificity and Concreteness capture two separate aspects involved in abstraction and that specificity may need to be controlled for when investigating conceptual concreteness. Finally, through a series of regression studies we show that specificity explains a unique amount of variance in decision latencies (lexical decision task), suggesting that this variable has theoretical value. The results are discussed in relation to the concept and investigation of abstraction.
Organization and marketing tools to increase sales of over-the-counter medicines in pharmacies
Authors: Katynska M. G. 
Published: September 2022

Pharmaceutical marketing is an activity aimed at meeting the needs of the population in pharmaceutical care. Relevant and specific for this industry promotion tool is recognized marketing mix – marketing complex, the components of which are 4P: product; price (cost); place and promotion.
These components are the most important in determining the marketing policy of each organization. The formation of the marketing complex of pharmacies has its own features, which are related to the specifics: the sale of over-the-counter and prescription medicines, patient health, ethics of promotion, and so on. The urgency of the topic is due to the active development of over-the-counter medicines as a special group for purchase and use, which is clearly reflected in the methods of sale.
Currently, merchandising in pharmacies as a modern type of pharmaceutical marketing is gaining special development. The object of research is the use of the principles of merchandising in a pharmacy. The subject of research – approaches, and means of sales promotion and increase sales of medicines in the application of the principles and rules of application of the principles of merchandising in the pharmacy.
Ischemic heart disease is the main cause of mortality in patients with cardiovascular diseases
Authors: Fedorov S. V. 
Published: September 2022

Ischemic heart disease is a leader in the structure of causes of both global and cardiovascular and sudden cardiac deaths. In recent years, there has been a steady increase in this figure around the world.
The article presents statistics on mortality due to coronary heart disease in different countries, including Ukraine, and its place in the structure of mortality for all reasons. The impact of the COVID-19 pandemic on the course and consequences of coronary heart disease is analyzed, as well as the recommendations of the European Society of Cardiology on the strategy of such patients.
Current guidelines for the high atherosclerotic risk patients management: chronic coronary syndrome and conditions after acute coronary events
Authors: Parkhomenko O. M. 
Published: September 2022

The article analyzes the latest recommendations of the European Society of Cardiology (ESC) on the management of patients with acute coronary syndrome without it and with ST-segment elevation (2020 and 2017, respectively), as well as on the diagnosis and management of chronic coronary syndrome ( 2019).
In order to increase the adherence to treatment of patients with chronic coronary syndrome and patients with acute coronary syndrome, after stabilization of their condition, it is advisable to use the concept of polyps (polypill) - a combination of several drugs in one tablet.
NEPTUNO STUDY: polypill Trinomia use decreased risk of major adverse cardiovascular events
Authors: Koval O. A. 
Published: September 2022

The article presents an overview of domestic and international research on the feasibility and effectiveness of using a strategy of combining several drugs with fixed doses in one pill - a polypill - in patients with cardiovascular diseases, in particular after an acute coronary syndrome, with the aim of secondary prevention of repeated adverse events .
The NEPTUNO study showed that the use of a cardiovascular combination drug containing acetylsalicylic acid, ramipril, atorvastatin (CNIC-Polypill) was associated with a significant reduction in the rate of recurrence of major adverse cardiovascular events, along with a delay in time to event, in in a large sample of real patients with a history of atherosclerotic cardiovascular disease in comparison with three different control groups of active treatment (monocomponent, equipotent and other therapy). In addition, the use of CNIC-Polypill provided better blood pressure and lipid control, as well as longer duration of continuous medication. The results of the NEPTUNO study confirmed the usefulness of this strategy for the secondary prevention of cardiovascular diseases.
Neurogeroprotection in neurological practice: new possibilities
Authors: Burchinsky S. G. , Kalinichenko М. A. 
Published: September 2022

The article is devoted to the issues of effective pharmacotherapy of neurodegenerative and vascular pathology of the CNS, which is possible due to the adequate impact on the fundamental mechanisms of brain aging. Comprehensive, comprehensive consideration of the mentioned mechanisms allows to reasonably approach the problem of optimization of neuroheroprotection and choice of a specific drug. Today, the most promising neuroheroprotectors are quercetin, L-carnitine and L-arginine. A rational combination of all three mentioned components is a domestic drug - L-ACC, which has no analogues in the pharmaceutical market.
The use of combined neurogeroprotectors, in particular L-ACC, opens up new prospects for expanding the adaptive-compensatory capabilities of the brain, slowing down its aging processes and the manifestation of age-related pathology, helps to increase the duration and quality of life, the formation of stress resistance and reduces the cost of treatment.
The assessment of the adherence to the treatment among military personnel with arterial hypertension, at the present stage
Authors: Tkachuk I.M. 
Published: September 2022

Purpose – to conduct an analysis of the adherence to the treatment among military personnel with arterial hypertension at the present stage.
Materials and methods. A random sampling questionnaire survey of 100 patients was conducted. Patients are male, aged between 22 and 86 years old, who recived the treatment within 2017 at the National Military Medical Clinical Center «The Main Military Clinical Hospital», having the diagnosis of hypertension. To study the age-related characteristics of adherence to the treatment of hypertension, patients were divided into two study groups: group I age 22–59 (46 patients); group II age 60–86 (64 patients). The questionnaire including a modified Morisky scale with six questions was used for the study and standardization of the campaign. Based on the results of the research a computer database was generated, and statistical processing of the data using the application software package with variational statistics methods using Student’s t-test was conducted. The primary processing for variable denominations and rank variables involved calculating the interest rate.
Results. Using the questionnaire method, it was found that adherence to the use of antihypertensive drugs was higher in patients over the age of 60 – regularly taking medication 83±5.1 %, in the group of under 60 – 26±6.5 % (p<0,05). The low level of servicemen’s motivation for treatment is proved.
Conclusions. The conducted research showed the presence of problematic issues among servicemen and military pensioners to adherence to treatment. The main ones are low motivation for treatment and a lower adherence to treatment in the age group under 60 years.
Liquid Smoke of Red Fruit (Pandanus Conoideus. L.) Waste with Pyrolysis Method For Controlling Sweet Potatoes (Ipomea Batatas. L.) Pest
Authors: DEWI Fransisca Christiana , TUHUTERU Sumiyati , ALADIN Andi , YANI Setiyawati , LESTARI Rohimah Handayani Sri , PADANG Irwan Suluk , SUBRATA Bhaskara Anggarda Gathot 
Published: September 2022

Pandanus conoidus, or red fruit, is a nutrient-dense native Papuan plant, whereas Ipomea batatas are the main food for the Wamena people. Biomass from red fruit seed waste can be used as liquid smoke to control Ipomea batatas . At a temperature of between 300 - 450 °C, liquid smoke is produced through a pyrolysis process. Pyrolysis produces phenolic chemicals and aldehydes that have antioxidant and antimicrobial properties (anti-bacterial and anti-fungal). The assessment of pH, acidity, and phenol concentration characterizes the quality of liquid smoke. The potential of red fruit seed waste as a liquid smoke product for biopesticides in Ipomea batatas is explored in this study. Additionally, study development aims to determine the optimal method for pyrolyzing red fruit seed waste, its characteristics, chemical content, and the way to use liquid smoke as a biopesticide in Ipomea batatas . The results showed that the liquid smoke of grade 3 red fruit seed waste contains 7 components that can be detected using a mass spectrometer. The higher the concentration of liquid smoke produced by grade 3 red fruit seeds, the higher the possibility of Cylas formicarius mortality. Cylas formicarius had the highest mortality rate (90%) when tested at a 7% test solution concentration.
Legal Protection For Consumers In Purchasing Homes From Default Actions Of The Developer
Authors: HADIATI Dian , SIHABUDIN Sihabudin , NURWIDHIYANTI Hanif 
Published: September 2022

Hundreds of victims of the alleged Quranic Residence housing fraud, in Kemang, Bogor Regency, demanded their money be returned immediately. The losses suffered by the victims reached 12 billion. The claim was submitted after they felt cheated by PT Alfatih Bangun Indonesia, as a housing developer under the guise of sharia. PT Alfatih Bangun Indonesia has defaulted on consumers and shirked its responsibilities. The house promised by the developer until now has not been built and is still in the form of vacant land. In accordance with the legislation on consumer protection, PT Alfatih Bangun Indonesia as a developer must compensate and even get criminal for his treatment. The purpose of this writing is to find out and analyze the legal protection of consumers for wanprestasi carried out by developers
Macklin as Theatre Manager
Authors: Kinservik Matthew 
Published: September 2022

This chapter explores the managerial dimension of Macklin’s long career. Although often overlooked, Macklin’s experiences in theatrical management were extensive, ranging from formal managerial duties as Charles Fleetwood’s lieutenant at Drury Lane to overseeing provincial companies and independent productions to serving as the impresario of his short-lived coffeehouse and lecture hall, the British Inquisition. This managerial activity was often entrepreneurial and helped to establish, sustain, and, ultimately, revive Macklin’s acting career. His involvement in the establishment of the Crow Street Theatre and the crucial success of his farce, Love à la Mode, are best understood in the context of his managerial activities. To fully appreciate Macklin’s contributions to the stage, he needs to be included in the group of significant actor/managers of the eighteenth century.
The AGEL Survey: Spectroscopic Confirmation of Strong Gravitational Lenses in the DES and DECaLS Fields Selected Using Convolutional Neural Networks
Authors: Tran Kim-Vy H. , Harshan Anishya , Glazebrook Karl , Vasan G. C. Keerthi , Jones Tucker , Jacobs Colin , Kacprzak Glenn G. , Barone Tania M. , Collett Thomas E. , Gupta Anshu , Henderson Astrid , Kewley Lisa J. , Lopez Sebastian , Nanayakkara Themiya , Sanders Ryan L. , Sweet Sarah M. 
Published: September 2022

Abstract
We present spectroscopic confirmation of candidate strong gravitational lenses using the Keck Observatory and Very Large Telescope as part of our ASTRO 3D Galaxy Evolution with Lenses (AGEL) survey. We confirm that (1) search methods using convolutional neural networks (CNNs) with visual inspection successfully identify strong gravitational lenses and (2) the lenses are at higher redshifts relative to existing surveys due to the combination of deeper and higher-resolution imaging from DECam and spectroscopy spanning optical to near-infrared wavelengths. We measure 104 redshifts in 77 systems selected from a catalog in the DES and DECaLS imaging fields (r ≤ 22 mag). Combining our results with published redshifts, we present redshifts for 68 lenses and establish that CNN-based searches are highly effective for use in future imaging surveys with a success rate of at least 88% (defined as 68/77). We report 53 strong lenses with spectroscopic redshifts for both the deflector and source (z
src > z
defl), and 15 lenses with a spectroscopic redshift for either the deflector (z
defl > 0.21) or source (z
src ≥ 1.34). For the 68 lenses, the deflectors and sources have average redshifts and standard deviations of 0.58 ± 0.14 and 1.92 ± 0.59 respectively, and corresponding redshift ranges of z
defl = 0.21–0.89 and z
src = 0.88–3.55. The AGEL systems include 41 deflectors at z
defl ≥ 0.5 that are ideal for follow-up studies to track how mass density profiles evolve with redshift. Our goal with AGEL is to spectroscopically confirm ∼100 strong gravitational lenses that can be observed from both hemispheres throughout the year. The AGEL survey is a resource for refining automated all-sky searches and addressing a range of questions in astrophysics and cosmology.
A Low-inclination Neutral Trans-Neptunian Object in an Extreme Orbit
Authors: Chen 陳 Ying-Tung 英同 , Eduardo Marielle R. , Muñoz-Gutiérrez Marco A. , Wang 王 Shiang-Yu 祥宇 , Lehner Matthew J. , Chang 章 Chan-Kao 展誥 
Published: September 2022

Abstract
We present photometric observations and numerical simulations of 2016 SD106, a low-inclination (i = 4.°8) extreme trans-Neptunian Object with a large semimajor axis (a = 350 au) and perihelion (q = 42.6 au). This object possesses a peculiar neutral color of g − r = 0.45 ± 0.05 and g − i = 0.72 ± 0.06, in comparison with other distant trans-Neptunian objects, all of which have moderate-red to ultra-red colors. A numerical integration based on orbital fitting on astrometric data covering eight years of arc confirms that 2016 SD106 is a metastable object without significant scattering evolution. Each of the clones survived at the end of the 1 Gyr simulation. However, very few neutral objects with inclinations <5° have been found in the outer solar system, even in the main Kuiper Belt. Furthermore, most mechanisms that lift perihelion distances are expected to produce a very low number of extreme objects with inclinations <5°. We thus explored the possibility that a hypothetical distant planet could increase the production of such objects. Our simulations show that no 2016 SD106–like orbits can be produced from three Kuiper Belt populations tested (i.e., plutinos, twotinos, and the Haumea Family) without the presence of a hypothetical planet, while a few similar orbits can be obtained with it; however, the presence of the additional planet produces a wide range of large semimajor-axis/large perihelion objects, in apparent contradiction with the observed scarcity of objects in those regions of phase space. Future studies may determine if there is a connection between the existence of a perihelion gap and a particular orbital configuration of a hypothetical distant planet.
Systematic Errors as a Source of Mass Discrepancy in Black Hole Microlensing Event OGLE-2011-BLG-0462
Authors: Mróz Przemek , Udalski Andrzej , Gould Andrew 
Published: September 2022

Abstract
Two independent groups reported the discovery of an isolated dark stellar remnant in the microlensing event OGLE-2011-BLG-0462 based on photometric ground-based observations coupled with astrometric measurements taken with the Hubble Space Telescope. These two analyses yielded discrepant mass measurements, with the first group reporting that the lensing object is a black hole of 7.1 ± 1.3 M
⊙ whereas the other concluded that the microlensing event was caused by either a neutron star or a low-mass black hole (1.6–4.4 M
⊙). Here, we scrutinize the available photometric and astrometric data and conclude that systematic errors are a cause of the discrepant measurements. We find that the lens is an isolated black hole with a mass of 7.88 ± 0.82 M
⊙ located at a distance of 1.49 ± 0.12 kpc. We also study the impact of blending on the accuracy of astrometric microlensing measurements. We find that low-level blending by source companions is a major, previously unrecognized, challenge to astrometric microlensing measurements of black hole masses.
Breakthrough Listen Search for the WOW! Signal*
Authors: Perez Karen I. , Farah Wael , Sheikh Sofia Z. , Croft Steve , Siemion Andrew , Pollak Alexander W. , Brzycki Bryan , Cruz Luigi F. , Czech Daniel , DeBoer David , Drew Jamie , Gajjar Vishal , Garrett Michael A. , Isaacson Howard , Lebofsky Matt , MacMahon David H. E. , Premnath Pranav H. , Pater Imke de , Price Danny C. , Schoultz Sarah , Wlodarczyk-Sroka Bart S. , Tarter Jill , Worden S. Pete 
Published: September 2022

Abstract
Caballero identified the star 2MASS 19281982-2640123 as a potential Sun-like star from which the WOW! signal could have originated. We conducted a search for artificial narrowband (2.79 Hz/1.91 Hz), drifting (±4 Hz s−1) technosignatures from this source using the turboSETI pipeline, from 1–2 GHz, using simultaneous multi-telescope observations with both the Robert C. Byrd Green Bank Telescope and the newly refurbished Allen Telescope Array on 2022 May 21. Both telescope observations had an overlap of 580 s. While blind searches using radio telescopes have been conducted in the general field of view in which the WOW! signal was first detected, this is the first time a targeted search has been done. No technosignature candidates were detected.
Abate application practices in the Guinea worm endemic region of Gambella, Ethiopia: identification of elimination gaps
Authors: Gindola Yamlak , Getahun Desalegn , Mohammed Khogali Ahmed , Kamau Edward Mberu , Camara Bienvenu Salim , Wossen Mesfin , Demissie Kassahun , Abdela Sintayehu , Gebrewold Gashaw , Hailu Girmay , Tegistu Mesfin , Okugn Akwoma , Gikilo Gnkikew 
Published: September 2022

Introduction: Guinea worm disease is caused by Dracunculus medinensis. Transmission of the disease depends on vectors (copepods). Abate applications in targeted water sources to control copepod is the main intervention. The aim of this study was to assess vector control practice in the guinea worm endemic region of Gambela, Ethiopia and to identify elimination gaps.
Methodology: Retrospective analysis of routine program data recorded from 2016 to 2020 was performed. Pre-and post-copepod test is conducted on water ponds to determine the density of copepods. Based on the copepod density, the chemical is applied accordingly. The five years data was obtained from Ethiopian public health institute electronic database with permission.
Results: A total of 22,131 water ponds were treated during the past five years. Out of the total treated in 2020, 4,669/7,266 (64%) were found with > 9 Copepods during pre-copepod test. 130/7,266 (1.79%) of water ponds which were post-tested after Abate application failed the requirement of scoring ≤ 9 copepods. Of the 130 water ponds, 115 (88.5%) were observed during the transmission season (April to November). Abate application trend had increased by 28.9% during the 5 years period. According to the database, some of the largest water sources found in infection reporting villages missed their 28 days regular treatment schedule.
Conclusions: A single water source that has not been treated effectively could be a source of infection for both humans and animals. The practice of Abate application should be enhanced and monitored regularly. The documenting system should be improved for quality, timely information and action.
Clinical pattern and treatment outcome of Cutaneous Leishmaniasis in two hospitals in Bahir Dar, Ethiopia (2017-2021)
Authors: Tesfa Debas , Manaye Nigus , De Vries Henry JC , Van Griensven Johan , Enbiale Wendemagegn 
Published: September 2022

Introduction: Cutaneous Leishmaniasis (CL) in Ethiopia is caused by a unique species, L. aethiopica. In Ethiopia, there are limited studies that provide detailed clinical descriptions of CL, treatment options, and treatment outcomes.
Methodology: We conducted a descriptive study based on routinely collected data in medical files from two hospitals in Bahir Dar, Ethiopia, from 2017 to 2021. Three months following the end of therapy, we retrieved sociodemographic and clinical data, as well as data on the treatment outcome.
Result: Between March 2017 and June 2021, 94 patients were diagnosed with CL at the two hospitals. Of those, 46 (48.9%) of individuals had localized CL, 36 (38.3%) mucocutaneous leishmaniasis (MCL), and 12 (12.8%) diffuse CL. Sixty-five (69.1%) of the participants were men. The most prevalent morphologic appearances were plaque (n = 42, 46.2%), nodule (n = 38, 41.8%), infiltrative (n = 34, 36.2%), crusted (n = 32, 34%), and ulcerated (n = 24, 25.5%). Scarred, volcanic, and patchy lesions were also documented. Systemic pentavalent antimonials were the most common treatment (n = 55, 58.5%), curing 21/38 (55%) of the patients. Pentavalent antimonials were also given intralesionally to seventeen patients (18.1%), with 15/16 (94%) of them being cured. Overall, 61% (40/66) of patients with documented treatment outcomes were cured.
Conclusions: As CL in Ethiopia has a wide array of clinical presentations, clinicians should be suspicious of patients from endemic areas who present with dermatologic manifestations. Physicians can employ local treatment as a first line before resorting to systemic therapy.