bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuroplasticity after upper-extremity rehabilitation therapy with sensory stimulation in chronic stroke survivors
Authors: Schranz Christian , Vatinno Amanda , Ramakrishnan Viswanathan , Seo Na Jin 
Published: July 2022

Abstract
This study investigated the effect of using subthreshold vibration as a peripheral sensory stimulation during therapy on cortical activity. Secondary analysis of a pilot triple-blinded randomized controlled trial. Twelve chronic stroke survivors underwent 2-week upper-extremity task-practice therapy. Half received subthreshold vibratory stimulation on their paretic wrist (treatment group) and the other half did not (control). EEG connectivity and event-related de-/resynchronization for the sensorimotor network during hand grip were examined at pre-intervention, post-intervention and follow-up. Statistically significant group by time interactions were observed for both connectivity and event-related spectral perturbation. For the treatment group, connectivity increased at post-intervention and decreased at follow-up. Event-related desynchronization decreased and event-related resynchronization increased at post-intervention, which was maintained at follow-up. The control group had the opposite trend for connectivity and no change in event-related spectral perturbation. The stimulation altered cortical sensorimotor activity. The findings complement the clinical results of the trial in which the treatment group significantly improved gross manual dexterity while the control group did not. Increased connectivity in the treatment group may indicate neuroplasticity for motor learning, while reduced event-related desynchronization and increased event-related resynchronization may indicate lessened effort for grip and improved inhibitory control. EEG may improve understanding of neural processes underlying motor recovery.
The fate of oceanic plateaus: subduction versus accretion
Authors: Yan Zhiyong , Chen Lin , Zuza Andrew V , Tang Jiaxuan , Wan Bo , Meng Qingren 
Published: July 2022

SUMMARYOceanic plateaus (or aseismic ridges) can be either subducted into the deep mantle, or accreted onto the overriding plate. Furthermore, some oceanic plateaus can change subduction mode from steep to flat-slab subduction. What factors control the fate of oceanic plateaus during subduction remain enigmatic. Here, we investigate the controls on these modes and their respective geological effects using 2-D thermomechanical simulations. We systematically examine the characteristics of an oceanic plateau (including crustal thickness and length), plateau-trench distance, convergence rate and eclogitization of the oceanic crust. Our models confirm that the size of the plateau and eclogitization are the main factors controlling the subduction characteristics. For the eclogite models, a relatively thin oceanic plateau (≤20 km thick) undergoes steep subduction, a moderate-scale plateau (25–30 km thick) favours flat-slab subduction and large-scale plateaus (≥35 km thick) are more susceptible to collide and accrete to the overriding upper plate. Eclogitization significantly reduces the formation chance and duration of flat-slab subduction. The switch from flat-slab to steep subduction occurs rapidly (&lt;5 Ma), and the steepening occurs twice as fast as the flattening. The plateau-trench distance determines the location of the break-off, and shallow break-off (&lt;300 km) of the frontal slab will significantly change the subduction pattern. Either fast convergence rates (≥8 cm yr−1) or overthrusting of the overriding plate promotes the formation of flat-slab subduction. The mode changed from flat-slab to steep subduction explains the landward migration of magmatism followed by a trenchward migration in Eastern China since the Mesozoic.
A graph-space optimal transport objective function based on q-statistics to mitigate cycle-skipping issues in FWI
Authors: da Silva S L E F , Karsou A , de Souza A , Capuzzo F , Costa F , Moreira R , Cetale M 
Published: July 2022

SUMMARY
Full-waveform inversion (FWI) is a powerful seismic imaging methodology to estimate geophysical parameters that honour the recorded waveforms (observed data), and it is conventionally formulated as a least-squares optimization problem. Despite many successful applications, least-squares FWI suffers from cycle skipping issues. Optimal transport (OT) based FWI has been demonstrated to be a useful strategy for mitigating cycle skipping. In this work, we introduce a new Wasserstein metric based on q-statistics in the context of the OT distance. In this sense, instead of the data themselves, we consider the graph of the seismic data, which are positive and normalized quantities similar to probability functions. By assuming that the difference between the graphs of the modelled and observed data obeys the q-statistics, we introduce a robust q-generalized graph-space OT objective function in the FWI context namely q-GSOT-FWI, in which the standard GSOT-FWI based on l2-norm is a particular case. To demonstrate how the q-GSOT-FWI deals with cycle skipping, we present two numerical examples involving 2-D acoustic wave-equation modelling. First, we investigate the convexity of q-GSOT objective function regarding different time-shifts, and, secondly, we present a Brazilian pre-salt synthetic case study, from a crude initial model which generates significant cycle-skipping seismic data. The results reveal that the q-GSOT-FWI is a powerful strategy to circumvent cycle skipping issues in FWI, in which our objective function proposal presents a smoother topography with a wider attraction valley to the optimal minimum. They also show that q-statistics leads to a significant improvement of FWI objective function convergence, generating higher resolution acoustic models than classical approaches. In addition, our proposal reduces the computational cost of calculating the transport plan as the q-value increases.
Source scaling comparison and validation in Central Italy: data intensive direct Swaves versus the sparse data coda envelope methodology
Authors: Morasca Paola , Bindi Dino , Mayeda Kevin , Roman-Nieves Jorge , Barno Justin , Walter William R , Spallarossa Daniele 
Published: July 2022

SUMMARY
Robustness of source parameter estimates is a fundamental issue in understanding the relationships between small and large events; however, it is difficult to assess how much of the variability of the source parameters can be attributed to the physical source characteristics or to the uncertainties of the methods and data used to estimate the values. In this study, we apply the coda method by Mayeda et al. using the coda calibration tool (CCT), a freely available Java-based code (https://github.com/LLNL/coda-calibration-tool) to obtain a regional calibration for Central Italy for estimating stable source parameters. We demonstrate the power of the coda technique in this region and show that it provides the same robustness in source parameter estimation as a data-driven methodology [generalized inversion technique (GIT)], but with much fewer calibration events and stations. The Central Italy region is ideal for both GIT and coda approaches as it is characterized by high-quality data, including recent well-recorded seismic sequences such as L'Aquila (2009) and Amatrice–Norcia–Visso (2016–2017). This allows us to apply data-driven methods such as GIT and coda-based methods that require few, but high-quality data. The data set for GIT analysis includes ∼5000 earthquakes and more than 600 stations, while for coda analysis we used a small subset of 39 events spanning 3.5 &lt; Mw &lt; 6.33 and 14 well-distributed broad-band stations. For the common calibration events, as well as an additional 247 events (∼1.7 &lt; Mw &lt; ∼5.0) not used in either calibration, we find excellent agreement between GIT-derived and CCT-derived source spectra. This confirms the ability of the coda approach to obtain stable source parameters even with few calibration events and stations. Even reducing the coda calibration data set by 75 per cent, we found no appreciable degradation in performance. This validation of the coda calibration approach over a broad range of event size demonstrates that this procedure, once extended to other regions, represents a powerful tool for future routine applications to homogeneously evaluate robust source parameters on a national scale. Furthermore, the coda calibration procedure can homogenize the Mw estimates for small and large events without the necessity of introducing any conversion scale between narrow-band measures such as local magnitude (ML) and Mw, which has been shown to introduce significant bias.
A model combining patchy saturation and moisture-induced elastic weakening with application to ultrasonic monitoring under varying water saturation
Authors: Geremia Davide , David Christian 
Published: July 2022

SUMMARYWater is known to induce weakening on the static mechanical properties of rocks. However, injection-based operations such as EGS or EOR are commonly monitored through seismic methods involving dynamic moduli. It is therefore important to understand and quantify the effect of water-weakening on dynamic properties. In this study, we performed water injection tests on microporous carbonate rocks (two chalks from the Mons Basin) with ultrasonic monitoring of P-wave velocity and attenuation in order to observe the evolution of the rock moduli with varying water saturation. Our experimental results were interpreted through (i) a classical patchy saturation or PS model and (ii) the same model coupled with water weakening effect through modulus reduction induced by surface energy decrease induced by water in the fluid–rock system, called the WW-PS model. We show that the WW-PS model can better fit the experimental data than the PS model for both selected chalks, but also the previously published data for Sherwood sandstone. Therefore fluid–rock interaction needs to be taken into account when dealing with a fluid not in equilibrium with the host reservoir in fluid injection operations. An extension to reservoir scale modelling is proposed to emphasize the potential impact of water weakening at larger scales.
Global centroid moment tensor solutions in a heterogeneous earth: the CMT3D catalogue
Authors: Sawade Lucas , Beller Stephen , Lei Wenjie , Tromp Jeroen 
Published: July 2022

SUMMARYFor over 40 yr, the global centroid-moment tensor (GCMT) project has determined location and source parameters for globally recorded earthquakes larger than magnitude 5.0. The GCMT database remains a trusted staple for the geophysical community. Its point-source moment-tensor solutions are the result of inversions that model long-period observed seismic waveforms via normal-mode summation for a 1-D reference earth model, augmented by path corrections to capture 3-D variations in surface wave phase speeds, and to account for crustal structure. While this methodology remains essentially unchanged for the ongoing GCMT catalogue, source inversions based on waveform modelling in low-resolution 3-D earth models have revealed small but persistent biases in the standard modelling approach. Keeping pace with the increased capacity and demands of global tomography requires a revised catalogue of centroid-moment tensors (CMT), automatically and reproducibly computed using Green's functions from a state-of-the-art 3-D earth model. In this paper, we modify the current procedure for the full-waveform inversion of seismic traces for the six moment-tensor parameters, centroid latitude, longitude, depth and centroid time of global earthquakes. We take the GCMT solutions as a point of departure but update them to account for the effects of a heterogeneous earth, using the global 3-D wave speed model GLAD-M25. We generate synthetic seismograms from Green's functions computed by the spectral-element method in the 3-D model, select observed seismic data and remove their instrument response, process synthetic and observed data, select segments of observed and synthetic data based on similarity, and invert for new model parameters of the earthquake’s centroid location, time and moment tensor. The events in our new, preliminary database containing 9382 global event solutions, called CMT3D for ‘3-D centroid-moment tensors’, are on average 4 km shallower, about 1 s earlier, about 5 per cent larger in scalar moment, and more double-couple in nature than in the GCMT catalogue. We discuss in detail the geographical and statistical distributions of the updated solutions, and place them in the context of earlier work. We plan to disseminate our CMT3D solutions via the online ShakeMovie platform.
Error estimates for seismic body wave delay times in the ISC-EHB Bulletin
Authors: Nolet Guust , van der Lee Suzan 
Published: July 2022

SUMMARYWe analyse the consistency of the delay time data in the most recent version of the ISC-EHB bulletin published by the International Seismological Centre covering the years 1964–2018. Considering that the delays are influenced by the lateral heterogeneity in the Earth’s mantle, we construct a tomographic matrix. We use singular value decomposition of the tomographic matrix for 19 707 dense clusters of earthquakes to compute objective estimates of the standard error from data that project into the null space and should be zero if there were no errors. Using a robust initial estimate of the standard deviation of the clustered delay times, we remove a small fraction of outliers before calculating the ultimate errors. We found that the errors depend on the type of body wave, depth of the earthquake (crust or mantle) and the number of decimals with which the arrival time was reported. Using these parameters, we distinguish 45 different classes of delay times for 11 different types of body waves. The errors of each class so divided generally follow a distribution that is approximately normal with a mean that ranges from 0.32 s for PKPbc waves from mantle earthquakes, to 2.82 s for S waves from shallow earthquakes bottoming in the upper mantle. The widths of the distributions of the errors themselves are small enough to serve in formal statistical quantification of the quality of fit in tomographic experiments.
The SGNH hydrolase family: a template for carbohydrate diversity
Authors: Anderson Alexander C , Stangherlin Stefen , Pimentel Kyle N , Weadge Joel T , Clarke Anthony J 
Published: July 2022

Abstract
The substitution and de-substitution of carbohydrate materials are important steps in the biosynthesis and/or breakdown of a wide variety of biologically important polymers. The SGNH hydrolase superfamily is a group of related and well-studied proteins with a highly conserved catalytic fold and mechanism composed of 16 member families. SGNH hydrolases can be found in vertebrates, plants, fungi, bacteria, and archaea, and play a variety of important biological roles related to biomass conversion, pathogenesis, and cell signaling. The SGNH hydrolase superfamily is chiefly composed of a diverse range of carbohydrate-modifying enzymes, including but not limited to the carbohydrate esterase families 2, 3, 6, 12 and 17 under the carbohydrate-active enzyme classification system and database (CAZy.org). In this review, we summarize the structural and functional features that delineate these subfamilies of SGNH hydrolases, and which generate the wide variety of substrate preferences and enzymatic activities observed of these proteins to date.
Characterization of the interaction of multivalent glycosylated ligands with bacterial lectins by biolayer interferometry
Authors: Picault Léo , Laigre Eugénie , Gillon Emilie , Tiertant Claire , Renaudet Olivier , Imberty Anne , Goyard David , Dejeu Jerome 
Published: July 2022

Abstract
The study of multivalent carbohydrate–protein interactions remains highly complicated and sometimes rendered impossible due to aggregation problems. Biolayer interferometry is emerging as a tool to monitor such complex interactions. In this study, various glycoclusters and dendrimers were prepared and evaluated as ligands for lectins produced by pathogenic bacteria Pseudomonas aeruginosa (LecA and Lec B) and Burkholderia ambifaria (BambL). Reliable kinetic and thermodynamic parameters could be measured, and immobilization of either lectin or ligands resulted in high quality data. The methods gave results in full agreement with previous isothermal titration calorimetry experiments, and presented strong advantages because they require less quantity and purity for the biomolecules.
Mnt1, an α-(1 → 2)-mannosyltransferase responsible for the elongation of N-glycans and O-glycans in Aspergillus fumigatus
Authors: Kadooka Chihiro , Hira Daisuke , Tanaka Yutaka , Chihara Yuria , Goto Masatoshi , Oka Takuji 
Published: July 2022

Abstract
The fungal cell wall is necessary for survival as it serves a barrier for physical protection. Therefore, glycosyltransferases responsible for the synthesis of cell wall polysaccharides may be suitable targets for drug development. Mannose is a monosaccharide that is commonly found in sugar chains in the walls of fungi. Mannose residues are present in fungal-type galactomannan, O-glycans, N-glycans, glycosylphosphatidylinositol anchors, and glycosyl inositol phosphorylceramides in Aspergillus fumigatus. Three genes that are homologous to α-(1 → 2)-mannosyltransferase genes and belong to the glycosyltransferase family 15 were found in the A. fumigatus strain, Af293/A1163, genome: cmsA/ktr4, cmsB/ktr7, and mnt1. It is reported that the mutant ∆mnt1 strain exhibited a wide range of properties that included high temperature and drug sensitivity, reduced conidia formation, leakage at the hyphal tips, and attenuation of virulence. However, it is unclear whether Mnt1 is a bona fide α-(1 → 2)-mannosyltransferase and which mannose residues are synthesized by Mnt1 in vivo. In this study, we elucidated the structure of the Mnt1 reaction product, the structure of O-glycan in the Δmnt1 strain. In addition, the length of N-glycans attached to invertase was evaluated in the Δmnt1 strain. The results indicated that Mnt1 functioned as an α-(1 → 2)-mannosyltransferase involved in the elongation of N-glycans and synthesis of the second mannose residue of O-glycans. The widespread abnormal phenotype caused by the disruption of the mnt1 gene is the combined result of the loss of mannose residues from O-glycans and N-glycans. We also clarified the enzymatic properties and substrate specificity of Mnt1 based on its predicted protein structure.
Breastfeeding-related neck pain: prevalence and correlates among Nigerian lactating mothers
Authors: Ojukwu Chidiebele Petronilla , Okpoko Chinechendu Glory , Okemuo Adaora Justina , Ede Stephen Sunday , Ilo Ijeoma Judith 
Published: July 2022

Abstract

Background
Breastfeeding (BF) is a physically demanding task and is predominantly performed in a head-down position as the mother attempts to maintain eye contact with the infant. There are possibilities of BF-related neck pain (BFRNP) that have not been widely studied. This study investigated the prevalence and correlates of BFRNP in Nigerian lactating mothers.

Methods
A cross-sectional descriptive survey was conducted among 310 lactating mothers selected from post-natal clinics in Enugu, Nigeria. Information on their BF profile was sought as well as the prevalence and characteristics of BFRNP using a self-structured questionnaire.

Results
It was found that cradle hold was the commonly adopted BF position (94.0%) and the majority breastfed ≥10 times daily (55.2%) for &lt;30 min per session (49.1%). BFRNP was seen in 51.7% of women, of which 55.0% reported moderate pain intensity and 60.0% experienced this pain during BF. None of the maternal characteristics and breastfeeding profiles were significantly associated with the prevalence of BFRNP (p&gt;0.05).

Conclusions
There is a high prevalence of BFRNP among nursing mothers. Although maternal characteristics and BF positions were not associated with reported BFRNP, the results suggest that changing BF positions reduces neck pain during nursing sessions. Therefore this study recommends that nursing mothers should regularly change their BF positions to increase relaxation and comfort.
What Can a Critical Cybersecurity Do?
Authors: Dwyer Andrew C , Stevens Clare , Muller Lilly Pijnenburg , Cavelty Myriam Dunn , Coles-Kemp Lizzie , Thornton Pip 
Published: July 2022

AbstractCybersecurity has attracted significant political, social, and technological attention as contemporary societies have become increasingly reliant on computation. Today, at least within the Global North, there is an ever-pressing and omnipresent threat of the next “cyber-attack” or the emergence of a new vulnerability in highly interconnected supply chains. However, such discursive positioning of threat and its resolution has typically reinforced, and perpetuated, dominant power structures and forms of violence as well as universalist protocols of protection. In this collective discussion, in contrast, six scholars from different disciplines discuss what it means to “do” “critical” research into what many of us uncomfortably refer to as “cybersecurity.” In a series of provocations and reflections, we argue that, as much as cybersecurity may be a dominant discursive mode with associated funding and institutional “benefits,” it is crucial to look outward, in conversation with other moves to consider our technological moment. That is, we question who and what cybersecurity is for, how to engage as academics, and what it could mean to undo cybersecurity in ways that can reassess and challenge power structures in the twenty-first century.
Inking Wartime: Military Tattoos and the Temporalities of the War Experience
Authors: Palestrino Mirko 
Published: July 2022

AbstractMilitary tattoos have recently become the latest genre of war art deployed by museums to make war tangible to their visitors. These new war objects give rise to important temporal inconsistencies: as individual soldiers relate different understandings of wartime, exhibitions mediate them monolithically, reproducing a notion of wartime as exceptional, finite, and temporary. To grasp this inconsistency, this article introduces a conceptual distinction between chronic and chronological embodied temporalities of war experience. In the four exhibitions of military tattoos under analysis, different veterans locate war's end at different junctures or moments. In these experiences, the issue of war's ending is a matter of chronology. In contrast, other veterans find war to be never-ending. In this case, war is akin to a chronic condition, whose very essence is a sense of temporal lingering that puts the idea of war's ending into question. I show that sticking to univocal understanding of wartime, exhibitions of military tattoos efface chronic and chronologically discrepant war experiences, contributing to the (re)production of a war/peace(time) binary that has been repeatedly deemed to be problematic and violent.