bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bing-Neel Syndrome: Real-Life Experience in Personalized Diagnostic Approach and Treatment
Authors: Kotsos Dimitrios , Chatzileontiadou Sofia , Apsemidou Athanasia , Xanthopoulou Anna , Rapi Aikaterini , Frouzaki Christina , Hatjiharissi Evdoxia 
Published: June 2022

The involvement of the central nervous system (CNS) in Waldenström’s Macroglobulinemia (WM) is a rare extramedullary manifestation of the disease known as Bing-Neel syndrome (BNS). To expand our understanding of this disease manifestation, we conducted a retrospective analysis of the incidence of BNS in 86 consecutive patients with WM [70% male, median age 65 years (range 33-86)] seen in our center during a 30-year period. Six patients (7%) from this group were diagnosed with BNS. The median period of time between WM diagnosis and BNS diagnosis was 6.8 years (range 2.3-15). They demonstrated a range of neurological deficits, including transient expressive aphasia, impaired vision, resting hand tremor, foot drop, and headache. Between the onset of symptoms and the diagnosis of BNS, the median time interval was 12.5 months (range 1-30). The diagnosis was made not on the basis of neurological symptoms or radiological evidence, but on the basis of the presence of WM cells in cerebrospinal fluid (CSF). Intrathecal chemotherapy with methotrexate, cytarabine, and dexamethasone (IT MTX, ARA-C, DEX) was used as front-line treatment, followed by intensive immunochemotherapy with rituximab, high-dose MTX, and ARA-C (R-Hi MTX/ARA-C) in three patients who were fit enough to receive this type of cytotoxic regimen, and rituximab plus bendamustine (R-Benda) in two patients who simultaneously required treatment for WM. Ibrutinib was administered to five patients (three as consolidation and two for initial treatment). All patients responded to front-line treatment, with four (67%) achieving partial response (PR) and two (33%) achieving complete response (CR). This study provides insight into the clinical presentation, diagnostic and treatment options, as well as the outcome of patients who have BNS.
Should Assessments of Decision-Making Capacity Be Risk-Sensitive? A Systematic Review
Authors: Berens Noah Clark , Kim Scott Y. H. 
Published: June 2022

BackgroundThe concept of decision-making capacity (DMC) or competence remains controversial, despite widespread use. Risk-sensitive DMC assessment (RS-DMC)—the idea that the higher the risk involved in a decision, the greater the decisional abilities required for DMC—has been particularly controversial. We conducted a systematic, descriptive review of the arguments for and against RS-DMC to clarify the debate.MethodsWe searched PubMed/MEDLINE (National Library of Medicine), PsycInfo (American Psychological Association) and Philpapers, updating our search to February 15th, 2022. We targeted peer-reviewed publications in English that argue for or against RS-DMC. Two reviewers independently screened the publications and extracted data from each eligible manuscript.ResultsOf 41 eligible publications, 22 supported a risk-sensitive threshold in DMC assessment. Most arguments for RS-DMC rely on its intuitive appeal and practical merits. The arguments against RS-DMC primarily express concerns about paternalism and the seeming asymmetry between consent and refusal; critics of RS-DMC support epistemic, rather than substantive (i.e., variable threshold), risk-sensitivity; counterarguments responding to criticisms of RS-DMC address charges of paternalism and exhibit a notable variety of responses to the issue of asymmetry. Authors used a variety of frameworks regarding the definition of DMC, its elements, and its relation to decisional authority, and these frameworks were significantly associated with positions on RS-DMC. A limitation of our review is that the coding relies on judgment and interpretation.ConclusionThe review suggests that some of the debate about RS-DMC stems from differences in underlying frameworks. Most defenses of RS-DMC rely on its intuitive appeal, while most criticisms reflect concerns about paternalism or the asymmetry between consent and refusal. Defenses of RS-DMC respond to the asymmetry problem in a variety of ways. Further research is needed on the implications of underlying frameworks, the asymmetry problem, and the distinction between epistemic and substantive models of RS-DMC.
Which Parameter Controls Ring Current Electron Dynamics
Authors: Haas Bernhard , Shprits Yuri Y. , Allison Hayley J. , Wutzig Michael , Wang Dedong 
Published: June 2022

Predicting the electron population of Earth’s ring current during geomagnetic storms still remains a challenging task. In this work, we investigate the sensitivity of 10 keV ring current electrons to different driving processes, parameterised by the Kp index, during several moderate and intense storms. Results are validated against measurements from the Van Allen Probes satellites. Perturbing the Kp index allows us to identify the most dominant processes for moderate and intense storms respectively. We find that during moderate storms (Kp < 6) the drift velocities mostly control the behaviour of low energy electrons, while loss from wave-particle interactions is the most critical parameter for quantifying the evolution of intense storms (Kp > 6). Perturbations of the Kp index used to drive the boundary conditions at GEO and set the plasmapause location only show a minimal effect on simulation results over a limited L range. It is further shown that the flux at L ∼ 3 is more sensitive to changes in the Kp index compared to higher L shells, making it a good proxy for validating the source-loss balance of a ring current model.
Individual and Community-Level Factors Associated With Intention to Use Contraceptives Among Reproductive Age Women in Sub-Saharan Africa
Authors: Asmamaw Desale Bihonegn , Eshetu Habitu Birhan , Negash Wubshet Debebe 
Published: June 2022

Objectives: The present study identifies factors that affect intention to use contraceptives among married women in countries in sub-Saharan Africa.Methods: Secondary data analysis was conducted using Demographic and Health Surveys. A total of 334386 weighted sample women who were fecund were included in the analysis. Multi-level mixed-effect logistic regression analysis was fitted to identify individual and community level factors associated with intention to use contraceptives.Results: The prevalence of intention to use contraceptives was 45.76%. Age, educational status, and wealth quintile were factors affecting the intention to use contraceptives.Conclusion: Several individual and community level factors were associated with the intention to use contraceptives in SSA. Therefore, governmental and non-governmental organizations should consider these factors when implementing strategies.
Sobre la universidad-empresa
Authors: Cadavid G. Teresa E. 
Published: June 2022

Hace ya varias décadas, Hanna Arendt, al hablar de la crisis en la cultura o en la “cultura de masas” de la moderna “sociedad de masas”, anotaba, entre otras cosas referidas al término, que el filisteísmo “denotaba una mentalidad para la que todo se debía juzgar en términos de utilidad inmediata y de `valores materiales´, y que por consiguiente no respetaba demasiado a obras y actividades tan inútiles como las que se dan en la cultura y el arte”.
Jawność wynagrodzenia jako aktualny problem społeczno-prawny
Authors: Kulikowski Konrad 
Published: June 2022

CEL NAUKOWY: Próba uporządkowania sposobów rozumienia jawności wynagradzania oraz nakreślenie jej kluczowych wymiarów, które należy brać pod uwagę planując polityki publiczne i tworząc regulaminy wynagradzania.
PROBLEM i METODY BADAWCZE: Zamieszanie terminologiczne związane z jawnością wynagrodzenia może prowadzić do tworzenia norm prawnych oraz regulaminów wynagradzania, które nie odpowiadają rzeczywistości społecznej i oczekiwaniom pracodawców oraz pracowników. W tekście dokonano krytycznego przeglądu znaczeń jawności wynagrodzenia, bazując na trzech źródłach: analizie jawności wynagrodzenia w polskim kontekście prawnym, analizie badań opinii polskiego społeczeństwa na temat jawności wynagrodzeń, analizie podejść do jawności wynagrodzeń w literaturze naukowej z zakresu badań organizacyjnych. Ujawnione znaczenia poddano analizie pojęciowej w celu ich uporządkowania i nakreślenia wymiarów jawności wynagrodzenia.
PROCES WYWODU: W pierwszej części artykułu zaprezentowano jawność wynagrodzeń jako aktualny problem na styku norm prawnych i oczekiwań społecznych. Następnie dokonano przeglądu znaczeń jawności w kontekście prawnym, społecznym i badań naukowych. W ostatniej części wyodrębniono wymiary jawności wynagrodzeń.
WYNIKI ANALIZY NAUKOWEJ: Uzyskane wyniki pokazują jawność wynagradzania jako pojęcie wieloznaczne i wskazują, że dla precyzyjnego jej rozumienia należy dookreślać ją w pięciu wymiarach: a) kogo ma dotyczyć, b) z jaką precyzją, c) w jakim stopniu dotyczyć ma wynagrodzenia finansowego, a w jakim pozafinansowego, d) w jakim stopniu dotyczyć ma procedur wynagradzania, e) jakie mają być zasady jej komunikowania.
WNIOSKI, INNOWACJE, REKOMENDACJE: Gdy wprowadzamy odwołanie do jawności wynagrodzeń, czy to w dyskursie publicznym, w kontekście stanowienia prawa i planowania polityk publicznych, czy to tworzenia regulaminów wynagradzania, powinniśmy jasno określić, o jakiej formie i zakresie jawności wynagrodzeń mówimy.
Tworzenie regulacji prawnych o przedsiębiorstwie społecznym w teorii demokracji deliberatywnej
Authors: Bohdziewicz - Lulewicz Marta , Murzyn Dorota , Pacut Agnieszka 
Published: June 2022

CEL NAUKOWY: Celem artykułu jest opis procesu tworzenia regulacji poświęconej przedsiębiorstwu społecznemu (PS) i ekonomii społecznej (ES), identyfikacja głównych aktorów i mechanizmów w kontekście założeń koncepcji demokracji deliberatywnej.
PROBLEM I METODY BADAWCZE: W artykule przeprowadzono analizę pojęciową i teoretyczną podstawowych założeń demokracji deliberatywnej, dialogu społecznego i dialogu obywatelskiego, przedsiębiorstw społecznych. W badaniu wykorzystano analizę źródeł pierwotnych (desk research), głównie projektów aktów prawnych w zakresie PS i ES i raportów z ich konsultacji.
PROCES WYWODU: W artykule przedstawiono kolejno: koncepcję przedsiębiorstwa społecznego i jego ramy prawne w Europie; założenia demokracji deliberatywnej i dialogu obywatelskiego w kontekście uczestniczenia obywateli w procesie stanowienia prawa; proces tworzenia regulacji poświęconej PS i ES w Polsce wraz z toczącymi się wokół niej dyskusjami środowiska związanego z ekonomią społeczną.
WYNIKI ANALIZY NAUKOWEJ: Proces tworzenia regulacji poświęconej PS i ES jest osadzony w koncepcji demokracji deliberatywnej. Zaangażowani byli w niego różni aktorzy, początkowo związani z sektorem społecznym, a później także publicznym różnych szczebli. W procesie tym wykorzystano zróżnicowane formy konsultacji i zaangażowania aktorów.
WNIOSKI, INNOWACJE, REKOMENDACJE: W toku analizy zidentyfikowano dwa modele inicjowania prac nad ustawą o PS i ES: model inicjatywy zewnętrznej i model mobilizacji. Ustalono że brak aktu prawnego może wynikać m.in. z: braku lidera koordynującego inicjatywę, niskiej motywacji i akceptacji środowiska ES dla idei PS, słabego rozpoznania koncepcji PS w społeczeństwie oraz heterogeniczności środowiska ES. Zasugerowano rozwinięcie badań w kontekście analizy grup interesu i ich wpływu na proces tworzenia ustawy.
Las Estrategias didáctico-pedagógicas basadas en la memoria ancestral muisca
Authors: Molano Caro Gladys 
Published: June 2022

La educación, como piedra angular de la sociedad, debe generar espacios de reflexión que propicien un verdadero reconocimiento de la diversidad étnica que lleve a un diálogo intercultural. En consecuencia, este artículo da cuenta de los resultados de una investigación que tuvo como objetivo comprender cómo a través del círculo de la palabra desde la tradición oral, se transmite el saber ancestral de la cultura muisca, fortaleciendo la interculturalidad en los niños de grado quinto de una institución de carácter oficial del municipio de Soacha[1]. El enfoque que acompañó el proceso fue el cualitativo; bajo el diseño de investigación-acción y el uso de una microetnografía lo cual posibilitó la consecución de resultados, en donde se destaca el diseño de tres (3) estrategias lúdico-pedagógicas digitales; la primera, una cartilla animada lúdico-digital; la segunda, una colección de podcast, y, la tercera, una colección de cuatro (4) video-cápsulas. Así mismo se debe resaltar el empoderamiento que se presentó por parte del grupo de estudiantes frente al reconocimiento de los antepasados muiscas que habitaron el territorio del municipio de Soacha desde el siglo VI a. C. contribuyendo al respeto hacia la diversidad intercultural.

[1] Soacha es un municipio anclado en el departamento de Cundinamarca en Colombia.
Simulation of analog resistance change characteristics in Pt/TaO
x
/Ta2O5/Pt cells
Authors: Nakamura Yuto , Nishi Yusuke 
Published: June 2022

Abstract
Resistive random access memories are strongly expected as not only an emerging nonvolatile memory but a neuromorphic device. However, the universal physical mechanism of resistance change phenomena has not been completely elucidated. In this study, we performed coupled simulation of analog resistance change phenomena in asymmetric Pt/TaO
x
/Ta2O5/Pt cells. We adopted a truncated cone-shaped conductive filament model and an appropriate amount of oxygen-vacancy storage in the Pt electrodes to demonstrate the gradual polarity swap of repeatable set and reset by control of the maximum negative voltage. As a result, mode control of the analog resistance change characteristics originates from an analog distribution inversion of the truncated cone-shaped filament without a clear depletion gap. The experimental and simulation results in this study indicate necessary conditions or dominant driving force of repeatable analog resistance change phenomena in the memristive cells.
To blunt or not to blunt: Still an outlawed practice in peripheral nerve blocks?
Authors: Munasinghe B M , Subramaniam N. 
Published: June 2022

Probably the first published account of regional nerve blocks was by Gaston Labat in 1922. Since the earlier experimentation, regional anesthesia has seen many ups and downs. The concept of field anesthesia popularized by the military anesthesiologists to be used in the battlefields, was quickly picked up by their colleagues working in the civil hospitals. The real breakthrough was brought about the invention of block needles to be used specifically for the peripheral nerve blocks, and proved to be safer than ordinary hypodermic syringe needles. The block needles, however, come at a higher price and the availability remains a constant problem, especially in the remote places of the low-income countries. The next revolution came with the advent of nerve stimulator and the ultrasound in the block techniques. Both of these developments really revolutionized the art of regional anesthesia. The authors describe a technique of use of blunted stylets of the ordinary intravenous cannulas. The technique can be used if resources are scarce, and with proper sterilization.
Key words: Cannula stylets; Blunting; Peripheral nerve blocks; Ultrasound-guided; COVID-19
Citation: Munasinghe BM, Subramaniam N. To blunt or not to blunt: Still an outlawed practice in peripheral nerve blocks? Anaesth. pain intensive care 2022;26(3):391-393. DOI: 10.35975/apic.v26i3.1913
Received: March 30, 2022; Reviewed: April 22, 2022; Accepted: May 05, 2022
Aplikasi Smart Posyandu Untuk Meningkatkan Kinerja Posyandu Sakura RW 29 Kelurahan Purwantoro Kecamatan Blimbing Kota Malang
Authors: Irmalia Suryani Faradisa  , Febriana Santi W  , Radimas Putra M. D. L.  
Published: June 2022

Pos Pelayanan Keluarga Berencana - Kesehatan Terpadu (Posyandu) adalah kegiatan kesehatan dasar yang diselenggarakan dari, oleh dan untuk masyarakat. Posyandu merupakan upaya kesehatan berbasis masyarakat (UKBM) yang dikelola, diselenggarakan, diorganisir dan dilaksanakan oleh masyarakat untuk pembangunan yang sehat guna meningkatkan kekuatan masyarakat dan memberikan sarana kepada masyarakat untuk memperoleh pelayanan social dasar. Dan juga pelayanan kesehatan untuk mempercepat penurunan angka kematian bayi dan anak. Bermacam kegiatan dilaksanakan oleh posyandu Antara lain: Kesehatan Iu dan Anak (KIA), Pemantauan Gizi, Immunisasi, KB dan penanggulangan diare. Kegiatan ini dapat ditambah atau dikembangkan di Posyandu yang lingkup kegiatannya masih dalam lingkup kegiatan utamanya dimana kegiatannya dapat dipilih dan disesuaikan dengan kebutuhan masyarakat setempat. Dengan banyaknya kegiatan yang dilaksanakan oleh para kader posyandu tersebut otomatis laporan yang dibuat jumlahnya tidak sedikit. Laporan ini harus disampaikan kepada pihak puskesmas maupun kelurahan sebagai lembaga yang menaungi Posyandu, dimana pelaporan ini akan dilakukan dalam jangka waktu sebulan sekali. Mengingat kegiatan pelaporan tersebut dilakukan secara rutin dan berlanjut serta jumlah berkas yang digunakan sebagai bahan pelaporan tidak sedikit, alangkah baiknya jika pencatatan data tersebut dilakukan dengan memanfaatkan teknologi informasi dengan harapan hal tersebut dapat membantu kader posyandu Sakura yang terletak di RW 29 Kelurahan Purwantoro Kecamatan Blimbing Malang dalam menyusun laporan. Berdasarkan hal tersebut timbul ide bagaimana cara untuk dapat membantu para kader dalam membuat laporan sehingga pekerjaan dari pada kader ini lebih mudah. Berdasarkan hasil wawancara dengan ibu ketua posyandu Sakura RW 29 Kelurahan Purwantoro Kecamatan Blimbing Kota Malang kami membuat sebuah aplikasi yang dapat terintegrasi antara HP dan komputer sehingga para kader ini nantinya dapat bekerja dengan lebih mudah dan lebih efesien dalam pembuatan laporannya
EFFECIENCY OF SILVER NANOPARTICALES AS ANTIBACTERIAL AGAINST AEROMONAS HYDROPHILA ISOLATED FROM INFECTED COMMON CARP
Authors: Suhail R. N. , Mustafa S. A. , AL-Obodi E.E. 
Published: June 2022

The present investigation was carried out to investigate the antibacterial efficiency of silver nanoparticles (AgNPs) in vitro against Aeromonas hydrophila using disc diffusion assay and minimum inhibitory concentration. The pathogenic A. hydrophila was isolated from infected common carp, usually diagnosed by chemical methods, and Avitek 2 compact device were used to confirm the diagnosis. The effectiveness of the prepared AgNPs was tested by chemical and biological (green synthesis using lemon extract) methods and were diagnosed by Fourier-transform infrared spectroscopy (FTIR), UV-Visible spectroscopy, Transmission electron microscopy (TEM), scanning electron microscope (SEM), which was spherical shape of the nanosilver and the size ranged between 30-50 nm. Results of disc diffusion assay showed that the chemical synthesized of AgNPs in 18hr recorded the highest inhibition zone followed by the bio-synthesized AgNPs and Oxytetracycline respectively. After 24 hr the highest inhibition zone was registered in Oxytetracycline, however after 5 days bio-synthesized AgNPs showed the higher inhibition zone which was significantly different(P≤0.05) in comparison to other products. Based on these results, both bio and chemical synthesized of AgNPs were effectively act as antibacterial against A.hydrophila. However, green synthesis using lemon extract is considered better antibacterial with low MIC than chemical AgNPs because lemon extract is regarded eco-friendly and also the low cost product compared to chemical AgNPs synthesis.
EFFICACY OF OREGANO OIL, CITRUS OIL AND DIGESTAROM® P.E.P. ON NEWCASTLE DISEASE INFECTION IN BROILERS
Authors: Alazzawi R. I. , Khammas E. J. 
Published: June 2022

The present study was carried out to detect efficacy of essential oils (oregano oil, anise oil, citrus oil and Digestarom® P.E.P) as an antiviral on Newcastle disease infection in broilers.One hundred twenty, one-day-old broiler chickens (Copp500) were used. On day twenty, the one hundred chickens were divided into six groups.Each group contained 20 birds. All chicks were challenged with median) virus titer embryo infectious dose (EID50) 1ml per bird intraocular, intranasal and orally of the isolated very virulent Newcastle disease virus that identified by (HA, HI test, PCR and ICPI) and treated with the essential oils blend level used in drinking water for five days after challenge, G1 oregano oil1ml/L , G2 anise oil 1ml/L, G3 citrus oil1ml/L, G4 Digestarom® P.E.P 0.17ml/L, G5 control positive, and G6 control negative without any treatment. The chickens were observed for clinical signs, gross lesion and weight until the end of the experiment.The result indicated that G4showed high protect than other oils with percentage 95% of survival chicks and mean weight 2054.42 gm, then G1 90% survival chickens and mean weight 1971.17gm, G2 85% survival chicks and mean weight 2148.88gm,G3 75% survival chicks and mean weight 2227.07gm while G5 protection was 60% with mean weight 1866.67gm and G6showed 100% mortality rate.The results illustrate that G4 and G1 were the best treatments which recorded significantly ( P≤0.01) followed by G2 and G3 respectively which recorded significantly (P≤0.05) in comparison with G5and G6.
REPRODUCTIVE PERFORMANCE IN RESPONSE TO DIFFERENT HORMONAL TREATMENTS IN LOCAL GOATS
Authors: Bamerny Araz O. , Alkass Jalal E. , Barwary Mwafaq S. 
Published: June 2022

To evaluate the effect of different hormonal treatments on reproductive performance of local goats, 60 adult does were synchronized by using sponges impregnated with 40 mg medroxy acetate (MAP) for 14 days. Following sponges withindrawn, the does were allocated randomly to four equal groups. The first group was served as control and intramuscularly injected with normal saline (T1). The does in group 2,3 and 4 were injected intramuscularly with 250 i.u hCG(T2) 400 i.u. eCG(T3) and 20 µg GnRH(T4), respectively. Results revealed that the highest estrus response was recorded in T2 (100%) followed by T4(93.3%), T1 (86.7%) and T3(73.3%). Fertility rate was significantly (p˂0.05) higher in T4 (93.3%) and the lowest was found in T3 (66.7%). A significantly higher kidding rate (146.7%) and litter size (1.69) was recorded in T2. While the lowest kidding rats and litter size was recorded in T4 and T3, respectively.
INVESTIGATE GENETIC RELATION AMONG WATERMELON CULTIVARS USING MOLECULAR DNA MARKERS
Authors: Elias M. S. , Al-Jubouri Kadhim D.H. 
Published: June 2022

This study was aimed to investigate genetic relation among 21 selective of watermelon seeds which collected from different commercial companies for different origins and produced at different years by using 12 primers for Inter Simple Sequence Repeat (ISSR). The results showed that the selective of Crimson sweet had genotypes highest genetic relation between ( K1 and K2) it was found less than the genetic similarity between ( K1and K4) , ( K2 and K4) .The four selective were divided two groups A and B. The results showed that the selective a Charleston gray had the highest genetic relation between (CH4 and CH6) while it found less than the genetic relation between (CH5 and CH9). The ten selectives were divided two cluster A and B,The groups A was divided three sub clusters .The results revealed that the highest genetic relation between the selective of the variety Sugar baby (S1and S3). While found less genetic relation between the (S1 and S5) and divided the selectives of Sugar baby into two main cluster A and B, The cluster B was divided two sub cluster. The result found that the highest genetic relation among the 21 selective it was between ( CH4 and CH6), while found less than of genetic similarity among ( CH8 and S5) ( CH8 and S2),( S2 and K1) ,( S2 and K2) ,( S2 and CH9),( K1 and S5) ( S5 and CH9). The 21 selectives was divided two main clusters A and B the group A was divided to three sub clusters while the group B was divided two sub clusters. It could be concluded that the genetic relation it is very important in the hybridization programs to it prove a large genetic base to benefit of plant breeding programs.