bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemical evidence for the tradeoff-in-the-nephron hypothesis to explain secondary hyperparathyroidism
Authors: Phelps Kenneth R. , Gemoets Darren E. , May Peter M. 
Published: August 2022

Background
Secondary hyperparathyroidism (SHPT) complicates advanced chronic kidney disease (CKD) and causes skeletal and other morbidity. In animal models of CKD, SHPT was prevented and reversed by reduction of dietary phosphate in proportion to GFR, but the phenomena underlying these observations are not understood. The tradeoff-in-the-nephron hypothesis states that as GFR falls, the phosphate concentration in the distal convoluted tubule ([P]DCT]) rises, reduces the ionized calcium concentration in that segment ([Ca++]DCT), and thereby induces increased secretion of parathyroid hormone (PTH) to maintain normal calcium reabsorption. In patients with CKD, we previously documented correlations between [PTH] and phosphate excreted per volume of filtrate (EP/Ccr), a surrogate for [P]DCT. In the present investigation, we estimated [P]DCT from physiologic considerations and measurements of phosphaturia, and sought evidence for a specific chemical phenomenon by which increased [P]DCT could lower [Ca++]DCT and raise [PTH].

Methods and findings
We studied 28 patients (“CKD”) with eGFR of 14–49 mL/min/1.73m2 (mean 29.9 ± 9.5) and 27 controls (“CTRL”) with eGFR > 60 mL/min/1.73m2 (mean 86.2 ± 10.2). In each subject, total [Ca]DCT and [P]DCT were deduced from relevant laboratory data. The Joint Expert Speciation System (JESS) was used to calculate [Ca++]DCT and concentrations of related chemical species under the assumption that a solid phase of amorphous calcium phosphate (Ca3(PO4)2 (am., s.)) could precipitate. Regressions of [PTH] on eGFR, [P]DCT, and [Ca++]DCT were then examined. At filtrate pH of 6.8 and 7.0, [P]DCT was found to be the sole determinant of [Ca++]DCT, and precipitation of Ca3(PO4)2 (am., s.) appeared to mediate this result. At pH 6.6, total [Ca]DCT was the principal determinant of [Ca++]DCT, [P]DCT was a minor determinant, and precipitation of Ca3(PO4)2 (am., s.) was predicted in no CKD and five CTRL. In CKD, at all three pH values, [PTH] varied directly with [P]DCT and inversely with [Ca++]DCT, and a reduced [Ca++]DCT was identified at which [PTH] rose unequivocally. Relationships of [PTH] to [Ca++]DCT and to eGFR resembled each other closely.

Conclusions
As [P]DCT increases, chemical speciation calculations predict reduction of [Ca++]DCT through precipitation of Ca3(PO4)2 (am., s.). [PTH] appears to rise unequivocally if [Ca++]DCT falls sufficiently. These results support the tradeoff-in-the-nephron hypothesis, and they explain why proportional phosphate restriction prevented and reversed SHPT in experimental CKD. Whether equally stringent treatment can be as efficacious in humans warrants investigation.
Queering the South on Screen, Tison Pugh (ed.) (2020)
Authors: Mittermeier Sabrina 
Published: August 2022

Review of: Queering the South on Screen, Tison Pugh (ed.) (2020)
Athens: University of Georgia Press, 302 pp.,
ISBN 9-780-82035-672-3, h/bk, $99.95
ISBN 9-780-82035-672-3, p/bk, $34.95
Contingent Figure: Chronic Pain and Queer Embodiment, M. D. Snediker (2021)
Authors: Welch Benedict 
Published: August 2022

Review of: Contingent Figure: Chronic Pain and Queer Embodiment, M. D. Snediker (2021)
Minneapolis, MN: University of Minnesota Press, 259 pp.,
ISBN 978-0-81669-190-6, p/bk, $27.00
Study of carbon nano-modifier of fly ash in cement concrete mixtures of civil engineering
Authors: Bieliatynskyi Andrii , Yang Shilin , Pershakov Valerii , Shao Meiyu , Ta Mingyang 
Published: August 2022

AbstractModern materials science has faced the problem of reducing the cost of raw materials and labor costs while obtaining basic construction materials (cement concrete) with increased performance properties. The article aims to substantiate the use of carbon nanotubes of fly ash as a cement concrete modifier to be reasonable for solving the above problem. Experimental studies are carried out using standard and special methods. The technological properties of cement concrete mixtures are determined in accordance with the European and American standards. The study investigates the impact of carbon nanotubes of fly ash on the structure and properties of the mineral Portland cement binder. The article provides the examination of structural and rheological characteristics of nano-modified cement concrete mixtures. The effect of a carbon nano-modifier on the strength, deformation, and performance properties of cement concrete mixtures is defined. As a result, the optimal composition of nano-modified cement concrete mixture has been developed that meets the criteria of concrete compressive strength and flowability. Positive research results allow determining the areas of application of the obtained compositions in civil engineering.
Clinical guidelines and expediency of using 5-aminolevulinic acid for intraoperative visualization of margins of malignant tumors of the oral cavity
Authors: Alymov Yu. V. , Ignatova A. V. , Romanov I. S. 
Published: August 2022

Introduction. Treatment of the oral cavity is an important problem of current oncology due to high morbidity and mortality reaching 43 % in 5-year period after diagnosis. frequency of positive resection margins is 30 % of cases which partially explains unsatisfactory results of therapy of this pathology and promotes investigation of methods increasing radicalness of surgical treatment of the primary lesion.The study objectiveis to evaluate the effectiveness of fluorescent visualization with 5-aminolevulinic acid for assessment of radicalness of surgical intervention in cancer of the oral mucosa.Materials and methods. In the study, evaluation of the effectiveness of 5-aminolevulinic acid for intraoperative determination of margins of squamous cell carcinoma of the oral mucosa (n= 36) was performed.Results. Comparison of intraoperative results using 5-aminolevulinic acid and results of histological examination showed that the difference in mean distances from the tumor edge to resection margin was 0.07 mm (95 % confidence interval 2.2905-2.4334) and wasn't statistically significant (p= 0.9519). Sensitivity of intraoperative fluorescent visualization with 5-aminolevulinic acid in diagnosis of resection margins was 100 %, specificity was 92.3 %, accuracy was 92.9 %, effectiveness was 96.1 %. Optimal effect of the fluorescent technique was achieved in patients with exophytic and mixed types of tumor growth without previous treatment.Conclusion. Method of intraoperative fluorescent visualization with 5-aminolevulinic acid showed high effectiveness (96.1 %) and can be recommended for intraoperative assessment of tumor margins and increase of radicalness of surgical treatment of cancer of the oral mucosa.
Búcsú Pusztai Ferenctől (1940–2021)
Authors: Kiss Jenő 
Published: August 2022

Korán, 81. életévében elment Pusztai Ferenc a minden halandók útján. Fájdalmas veszteség ez nem csupán családtagjainak, hanem barátainak, tanítványainak, munkatársainak is.
Benkő Loránd emléktáblája előtt
Authors: Kiss Jenő 
Published: August 2022

Benkő Loránd, a magyar nyelvtudomány kiemelkedő tudósa volt, aki száz évvel ezelőtt született és tíz éve már nincs közöttünk. A pesti egyetem bölcsészkarán 1946 óta dolgozott, 1959-től tanszékvezető egyetemi tanárként, nyugalomba vonulása után, amely nem jelentette tudományos tevékenységének a végét, emeritus professzorként. A Magyar Tudományos Akadémiának 46 éven át volt tagja. Idén, a centenáriumi évben jött el az idő, hogy emléktáblával is tisztelegjünk a magyar nyelvtörténet iskolateremtő alakjának az emléke előtt.
Pengaturan Rujuk Di Indonesia, Malaysia, Brunei Darussalam Dan Singapura
Authors: Mariani Mariani 
Published: August 2022

Abstract: A period in which the divorce happens at a legal marriage where a husband makes an approach to his ex-wife to make relationship as a couple of marriage (husband and wife) before her iddah period, in Islam, is called “Rujuk” (reconciliation). It can be done by a husband to his ex-wife if in period of first or second divorce. In the life of Indonesian government, rujuk is regulated and protected by Indonesian regulation, that is, UU No. 32/ 1954. Besides, it is regulated in Inpres No. 1/ 1991 Chapter XVIII Article 163-169 KHI. So in Malaysia, Brunei Darussalam, and Singapore, each has its own regulation. The method used in this research is qualitative method. It is found that the regulation of reconciliation (rujuk) in Southeast Asia, especially, Indonesia, Malaysia, Brunei Darussalam, and Singapore has similarity in following fiqh madzhab, namely, Syafi’i madzhab. This research also discusses the definition of rujuk according to fuqaha, implementation of rujuk according to Islamic law, rujuk in positif law in Indonesia, Malaysia, Brunei Darussalam, and Singapore Abstrak: Fase di mana terjadi perceraian pada sebuah perkawinan yang sah dan suami mendekati kembali kepada mantan isterinya untuk menjalin hubungan sebagai pasangan suami isteri sebelum masa iddahnya , dalam konsep agama disebut “Rujuk”, ini bisa dilaksanakan oleh suami kepada isterinya , apabila masih posisi talak satu atau talak dua,. Dalam kehidupan bernegara di Indonesia rujuk diatur dan dilindungi oleh perundang-undangan RI, yaitu Undang-undang No. 32 Tahun 1954, selain itu rujuk juga diatur dalam Instruksi Presiden No 1 Tahun 1991 Bab XVIII dalam pasal 163 sampai dengan pasal 169 KHI, begitu juga di Negara Malaysia, Brunai Darussalam dan Singapura.msing masing memiliki aturan tersendiri. .Metode yang digunakan dalam penelitian ini yaitu metode deskriptif kualitatif, sehingga didapatkan hasil riset berupa Pengaturan rujuk di negara Asia Tenggara khususnya Malaysia, Brunai Darussalam dan Singapura memiliki kesamaan dalam penggunaan madzhab yaitu madzhab Syafi’i Dalam Jurnal ini juga membahas terkait pengertian rujuk menurut para ahli fiqh, teknis pelaksanaan rujuk menurut hukum Islam, Rujuk Dalam Hukum Positif, Indonesia, Malaysia, Brunai Darussalam dan Singapura
THE CONCEPT OF MAHABBAH OF ABDUS SHAMAD AL-PALIMBANI IN FACING THE SPIRITUAL CRISIS OF MODERN MAN
Authors: Ihsan Nur Hadi , Abitolkhah Amir Maliki , Rahma Indah Maulidia 
Published: August 2022

Modern man's spiritual crises is a fascinating topic that is constantly pertinent to be discussed nowadays. The promise of a remedy to this modern dilemmas is even more intriguing. Abdus Shamad al-Palimbani is a prominent Sufi figure in the Malay Indoneaian Archipelago, with Sufi mahabbah teaching that is favorable to resolving this spiritual crisis. This work aims to explore the notion of mahabbah of al-Palembani and its significance in overcoming modern humans' spiritual dilemmas. This study is library research using qualitative approach. The data wer collected utilizing documentary techniques referring to boks, articles, and other published materials. The acquired data is then analyzed employing the descriptive-analytical method. This study finds that according to Abdus Shamad, human love is divided into stages, starting with love for others, wealth, family and relations, self-love, and love for Allah and His Messenger. If a man is bound by the four worldly degrees of love, he will suffer a spiritual crisis. Only by achieving the ultimate level of love, mahabbatullah, can he discover his own self, both material and spiritual.
Personalised treatment for epilepsy: gender-specific comorbid emotional disturbances in drug-resistant epilepsy in neurosurgical patients
Authors: Bannikova V. D. , Samochernykh K. A. , Dengina N. O. , Odintsova G. V. 
Published: August 2022

Background. Because of the apparent frequency and impact on patients’ quality of life, it is important to investigate the emotional domain of neurosurgical patients with drug-resistant epilepsy. The objective of this study was to investigate gender-specific signs of depression and anxiety in neurosurgical patients with drug-resistant epilepsy.Design and methods. In 2019–2020, Polenov Neurosurgical Institute studied comorbid emotional disturbances in 46 neurosurgical patients with drug-resistant epilepsy in two gender groups: Group 1 — male patients and Group 2 — female patients, using HADS, GAD-7, and Beck’s Depression Inventory in-depth screening.Results. The mean age of participants in the study was 30.8 ± 7.1 years. The male-to-female ratio was 1.5 to 1. The disease lasted an average of 19.2 years, with a mean age of onset of 11.7 years. HADS: normal in 74 % and 61 % of cases, subclinical anxious/depressed in 10 % and 17 % of cases, and clinical anxious/depressed in 16 % and 22 % of cases, respectively. On the GAD-7 scale, 57 % and 50 % were minimally anxious, 25 % and 11 % mildly anxious, 7 % and 33 % moderately anxious and 11 % and 6 % severely anxious. On the Beck’s Depression Inventory, 50 % and 37 % had no depressive symptoms, 32 % and 26 % had mild depression, 7 % and 23 % had moderate depression, 7 % and 5 % had severe depression, and 4 % and 9 % had clinical depression. Personalisation of treatment approaches for patients with affective disorders is driven by two key points: the inclusion of medications with antidepressant and antianxiety effects in addition to AEDs, and consideration of the effect of a given AED on the emotional domain.Conclusion. Among neurosurgical patients with drug-resistant epilepsy, patients without symptoms of anxiety and depression predominate in both male and female patients. In the long-term course of drug-resistant epilepsy, the gender differences in the emotional range of patients flatten out. There is a need to expand the sample and further investigate gender characteristics of neurosurgical patients in order to personalise the treatment of drug-resistant epilepsy.
Influence of Varieties and Spacings on Growth, Yield Attributes and Productivity of Pigeonpea
Authors: Bansal Kanik Kumar , Sandhu Kanwaljit Singh , Bharti Vijay , Saha Anuradha , Srivastava Hritik , Nesar Nesar Ahmad , Attri Meenakshi 
Published: August 2022

Background: The field experiment was conducted to evaluate pigeon pea varieties viz., AL 882 and Pusa Arhar 16 under different spacing in Amritsar region” during kharif season 2019-2020 at Students’ Research Farm, Department of Agriculture, Khalsa College, Amritsar. Methods: The experiment was laid out in Randomized Block Design (factorial), replicated thrice. There were six treatments of spacing S1 (30 × 12.5), S2 (40 × 12.5), S3 (50 × 12.5), S4 (30 × 25), S5 (40 × 25), S6 (50 × 25cm) and two varieties V1 (Pusa Arhar 16) and V2 (AL 882). All the cultural practices were performed to get maximum productivity of pigeonpea from each plot. Result: The results revealed that cv. AL 882 performed better under spacing 30 × 12.5 cm for growth parameters such as plant height and LAI whereas dry matter accumulation, crop growth rate and number of primary and secondary branches were significantly higher in spacing 50 × 25 cm. Among yield attributes, cv. AL 882 showed significantly higher number of pods per plant, pod length (cm), number of seeds per plant and 100 seed weight (g) under spacing 50 × 25 cm than cv. Pusa Arhar 16. However, seed yield was maximum in wider spacing (50 × 25 cm) and narrow spacing (30 × 12.5 cm) with cv. AL 882 and Pusa Arhar 16, respectively. However, both varieties produced highest stover and biological yield under narrow spacing 30 × 12.5 cm.
Fluid Identification Derived from Formation Chlorine Measurements and Reservoir Characterization of Tight Carbonate in Sichuan Basin, China
Authors: Wang Y. , Zhao X. R. , Li K. X. 
Published: August 2022

Summary
Natural gas production in the Sichuan Basin reached 30×109 m3 in 2020, but the shortfall between this and the production goal of 50×109 m3 in 2025 requires further exploration. The complex mineralogy and low porosity in tight carbonate reservoirs reduce the accuracy of formation water saturation calculations from Archie’s equation, which brings uncertainties to the reservoir characterization. Therefore, it is necessary to incorporate other methods as supplements to methods based on resistivities.
In this paper, we outline a method that incorporates wireline-induced gamma spectroscopy, nuclear magnetic resonance (NMR), array dielectric, and borehole images. Spectroscopy is not only used to estimate the mineralogy of the reservoir, but it also provides measurements, such as chlorine concentration and thermal neutron capture cross section (sigma). The amount of chlorine in the formation is proportional to the water volume in the reservoir, hence formation water saturation. Sigma is also an indicator of the formation water saturation. It enables formation water saturation calculation without resistivity measurements.
Case studies are presented from carbonate reservoirs in the Sichuan Basin, China. A robust and comprehensive petrophysical description of mineralogy, porosity, pore geometry, free fluid volume, rock type, and formation water saturation is presented. Calculation of formation water saturation from chlorine and sigma proves to be successful in both water-based mud and oil-based mud (OBM) environments. The depth of investigation (DOI) of chlorine from spectroscopy is about 8 to 10 in. for 90% of the signal. The various DOIs of different measurements must be considered when performing the fluid identification. Bound fluid saturation can reach more than 50% in tight carbonate reservoirs. Formation water saturation is not the only factor that determines the fluid type. Free fluid saturation from NMR must also be incorporated. Finally, a robust methodology integrating formation water saturation derived from dielectric and spectroscopy, and free fluid saturation derived from NMR shows great advantage in fluid identification in tight carbonate reservoirs.
In this paper, we discuss a novel combination of wireline logging tools for fluid identification in a tight carbonate reservoir in the Sichuan Basin. It reduces the uncertainty when estimating formation water saturation and when resistivity measurements are suppressed in OBM environments. The gas zones identified by the new method have promising predictions of gas production. This workflow can also be applied to other tight carbonate plays in China.
Application of Hydrothermal Liquefaction Procedure for Microalgae-To-Biofuel Conversion
Authors: Kelechi Faith Mmesomachukwu , Nwafor Chukwuebuka Samuel 
Published: August 2022

Abstract
The thermal depolymerization process is also known as Hydrothermal liquefaction(HTL) Is used in converting macro/micro molecules, under temperatures of about 280°C and 370°C and pressures that are in the range from 10 to 25 MPa and into crude such as oil. The oil is composed of high energy density and low heating values of 33.8-36.9 MJ/Kg and 5-20 wt% renewables and oxygen. Presently microalgae are used industrially in producing high-quality products for food additives. Also, the microalgae are environmentally friendly, as it is used in the treatment of wastewater, control in the mitigation of industrial CO2 emission and atmospheric CO2 capturing. Due to environmental issues, microalgal are converted from biomass to biofuel. Recently HTL has drawn more attention, as it can be used in the refinery industry. This paper is also concerned with solving environmental issues using microalgae as an effective method for biomass to biofuel conversion. One significant advantage of HTL is the possibility of using fresh microalgae after harvesting, the processing of biomass and increased thermodynamic efficiency. The latter is achieved due to high HTL temperature and pressure which creates an avenue for more heat recovery.
Transscleral vs endoscopic cyclophotocoagulation: safety and efficacy when combined with phacoemulsification
Authors: Nirappel Abraham , Klug Emma , Neeson Cameron , Chachanidze Mari , Hall Nathan , Chang Ta C. , Shen Lucy Q. , Valle David Solá-Del 
Published: August 2022

Abstract
Purpose
To compare the effectiveness and safety of phacoemulsification combined with endoscopic cyclophotocoagulation (phaco/ECP), phacoemulsification combined with MicroPulse transscleral cyclophotocoagulation (phaco/MP-TSCPC), and phacoemulsification alone (phaco) in the treatment of coexisting cataract and glaucoma.
Methods
Retrospective cohort study of consecutive cases at Massachusetts Eye & Ear. The main outcome measures were the cumulative probabilities of failure between the phaco/ECP group, phaco/MP-TSCPC group, and the phaco alone group with failure defined as reaching NLP vision at any point postoperatively or the inability to maintain ≥ 20% IOP reduction from baseline with IOP between 5–18 mmHg. Additional outcome measures included changes in average IOP, number of glaucoma medications, and complication rates.
Results
64 eyes from 64 patients (25 phaco/ ECP, 20 phaco/ MPTSCPC, 19 phaco alone) were included in this study. The groups did not differ in age (mean 71.04 ± 6.7 years) or length of follow-up time. Primary open-angle glaucoma was the most common type of glaucoma in the phaco alone (42%) and phaco/ECP (48%) groups while mixed-mechanism glaucoma was the most common type in the phaco/MP-TSCPC group (40%). The mean IOP reductions at 1 year were 3.07 ± 5.3 mmHg from a baseline of 15.78 ± 4.7 in the phaco/ECP group, 6.0 ± 4.3 mmHg from a baseline of 18.37 ± 4.6 in the phaco/MP-TSCPC group and 1.0 ± 1.6 from a baseline of 14.30 ± 4.2 mmHg in the phaco alone group. Surgical failure was less likely in eyes in the phaco/MP-TSCPC and phaco/ECP groups compared to phaco alone based on the Kaplan-Meier survival criteria, with failure defined as the inability to maintain an IOP reduction of 20% or more with IOP between 5–18 mm Hg long term. There were no differences in complications among the three groups.
Conclusions
Phaco/MP-TSCPC appears to provide for greater long-term IOP control than phaco alone and phaco/ECP. All three procedures had similar safety profiles.
Phylogeography and colonization pattern of subendemic round-leaved oxeye daisy from the Dinarides to the Carpathians
Authors: Konowalik Kamil 
Published: August 2022

Abstract
The Carpathians are an important biodiversity hotspot and a link between mountain ranges on the European continent. This study investigated the phylogeography of one the Carpathian subendemics, Leucanthemum rotundifolium, which is distributed throughout the range and in one isolated population outside it. Range-wide sampling was used to examine phylogeographic patterns by sequencing uniparentally inherited chloroplast markers that exemplify seed dispersal. Reconstruct Ancestral State in Phylogenies (RASP) software, Bayesian binary Markov Chain Monte Carlo (BBM) analysis, and ecological niche modeling based on concatenated results of five algorithms were used to infer migration routes and examine links with other species through phylogeny. The round-leaved oxeye daisy is an example of organisms that reached the Carpathians through a southern “Dacian” migration route, most probably through long-distance dispersal. Dating placed the events in the Pleistocene and supported migrations during cooler periods and stasis/isolation followed by separation in the interglacials. Haplotype diversification indicated that after L. rotundifolium reached the area around the Fagaras Mountains, several migration events occurred leading to colonization of the Southern Carpathians followed by migration to the Apuseni Mountains, the Eastern Carpathians, and finally the Western Carpathians. The results are consistent with previous phylogeographic studies in this region and indicate several novel patterns.