bluuebunny/crossref_metadata_2025_split huggingface dataset:
Análisis de la expresión oral, fluidez y comprensión lectora en un estudiante con discapacidad intelectual: estudio de caso
Authors: Vásquez Diego Rocío Anahí , Moreno Luna Flor de María , Hernández Díaz Reynaldo 
Published: March 2022

El presente artículo tiene como propósito analizar el proceso y alcance de los factores sobre la lectura como: la expresión oral, la fluidez y comprensión lectora en un estudiante con discapacidad intelectual de sexto grado de primaria con atención en el servicio de USAER. La estrategia implementada de intervención pedagógica se realizó en la ciudad de Oaxaca, a través de los instructivos con visión cognitiva, al considerar que la comprensión y fluidez de un texto requiere el desarrollo del pensamiento en vertientes ópticas, perceptuales, sintácticas y de significado. La estructura metodológica fue retomada desde la perspectiva del estudio de caso propuesta por Stake (1999), al compaginar todos los elementos observables en la amplitud del caso y retomar una investigación cualitativa en la recogida de datos mediante la aplicación de instrumentos de campo. Para la amplitud y profundidad del caso se retomaron los pilares de la observación, reflexión, planificación, acción y evaluación al cohesionar estos elementos y comprender la particularidad del caso-estudio. Los resultados obtenidos fueron mediante la triangulación de las directrices aportadas por los maestros involucrados para el desglose de los objetivos logrados.
Water, culture and identity. The recovery of former Cagliari’s racecourse area, Italia
Authors: Borea Francesca 
Published: March 2022

The former racecourse of Cagliari, inaugurated in 1929, occupies an area of about 24 hectares and is located between the Poetto beach and the Molentargius-Saline Regional Natural Park (one of the most important wetlands in Europe). Although the racetrack has been inactive since 2004, the intended use of this site remains linked to equestrian activity, a discipline deeply alive and rooted in Sardinian culture. The research called "Inhabited Ruin”, the starting point of this article, examines a place immersed in the heart of a natural context and aims to promote and reveal the original function of the site, leveraging its strategic position within the park. Currently the beach and the park, although limiting, are still two distinct realities given the scarcity of paths and infrastructures that allow these sites to be connected to each other. Re-evaluating this structure and integrating it into the surrounding context, in architectural and program terms, would allow the enhancement of the entire area with a more cohesive and integrated system (beach area, park and horse racing activities).
This project interprets the culture of the game of horse racing in a contemporary key, involving the element of water - so faithful to the site - for its restorative power, studying and taking as a model different places that in history have hosted similar events (for example Italian squares such as Piazza del Campo in Siena, Piazza dell'Anfiteatro in Lucca and Piazza Navona in Rome. The charm and success of these places, demonstrate how the private sphere of residential complexes can be actively involved in public life and entertainment venues become the example and inspiration to recover the existing site and transform it into a new environment that adequately integrates natural elements and built to give a unique character to this area of Cagliari.
Vaccination Against COVID-19 Disease During Pregnancy
Authors: Voiniušytė Austėja , Černiauskaitė Miglė , Paliulytė Virginija , Einikytė Rūta , Ramašauskaitė Diana 
Published: March 2022

Background. The effect of COVID-19 disease during pregnancy is still under investigation, however scientific studies have shown that pregnant women with COVID-19 infection are at increased risk for severe illness or complications [1]. Risk factors for severe disease and death in pregnancy include maternal age (especially ≥35 years), obesity, preexisting medical comorbidities (particularly hypertension and diabetes or more than one comorbidity), and being unvaccinated [2]. Many societies of obstetricians and gynecologists recommend that all pregnant patients undergo COVID-19 vaccination [1]. The aim of this study is to observe demographic characteristics, including education, place of residence and type of employment of women who chose to be vaccinated against COVID-19 in Lithuania, as well as to investigate any adverse reactions following the COVID-19 vaccine during pregnancy and compare the results to published scientific data.Materials and methods. An online questionnaire for pregnant women primarily located in Lithuania who received at least one dose of COVID-19 vaccine before giving birth has been launched in July, 2021. Data were entered via Google Forms and analyzed using Microsoft Excel and IBM SPSS Statistics. Literature review was performed on PubMed and Google Scholar search engines on inclusion criteria: publication date 2019–2021, used keywords pregnancy, COVID-19, vaccination, side effects.Results. Data were collected from 227 women vaccinated against COVID-19 during pregnancy. It was observed that the most chosen vaccine was Pfizer-BioNTech BNT162b2 (196 out of 227 individuals (86%)). More pregnant women confirmed having fever after the second dose compared to the first dose (p=0.006). In addition, injection site pain was the most common local side effect after both doses (98%) and more common after the first dose compared to the second (p=0.002). Regarding systemic reactogenicity more women experienced fatigue after the second dose comparing to the first dose (p=0.01). Furthermore, more women were unable to engage in daily activities after the second dose (p=0.03). All other symptoms did not differ after doses 1 and 2.Conclusions. Overall findings of this study did not suggest any obvious safety signals among pregnant individuals who received COVID-19 vaccine and all the side effects were comparable to the general population. Completed literature review indicates that pregnant women vaccinated against COVID-19 experience the same side effects as individuals in general population and no specific postvaccination reactions among pregnant individuals are observed.
Correcting the Background Tilt Signal of the Horizontal Seismometer Using a Rotation Sensor
Authors: Lin Chin-Jen , Ku Chin-Shang , Chi Tsung-Chih , Huang Bor-Shouh , Huang Hsin-Hua , Liu Chun-Chi 
Published: March 2022

Abstract
In observational seismology, the long-period background noise level in horizontal seismometer components is always higher than the vertical component at the same location. It is believed that the horizontal long-period noise is mostly attributed to ground tilt, yet the authentic tilt recordings of background noise in the seismic frequency band (0.01–20 Hz) have not been recorded successfully. We demonstrate the use of a newly developed optical-based rotation sensor, blueSeis-3A, to correct for the tilt effect in a horizontal seismometer. A station with a horizontal long-period (1 &lt; T &lt; 100 s) background noise level higher than the global new high-noise model was chosen, where a seismometer, a tiltmeter, and a rotation sensor were collocated. We first confirmed that the horizontal recordings from a tiltmeter and a seismometer were visually consistent, although it was unclear if tilt contamination existed in both recordings. It became evident until the ground tilt recorded by a rotation sensor was found to be waveform-matched with them, indicating that both sensors were contaminated by tilt. The spectrum of tilt records showed that ground tilts were mostly at period bands &gt;1 s. By subtracting tilt from seismometer records, the horizontal background noise levels could be improved, approximately to the resolution level of the rotation sensors. Our results demonstrate that collocating rotation sensors with seismometers is a feasible way to improve the quality of the long-period background noise level in seismometer horizontal components when rotation sensors are sufficiently sensitive.
A study to assess the level of stress among nursing students of IUST during COVID-19 pandemic
Authors: Mir Javaid Ahmad , Parveen Asmat , Wani Suheel Rashid , Nisar Tayyibah , Majeed Sakeena , Kausar Wahida , Islam Basit Ul 
Published: March 2022

Stress is a universal phenomenon to which every individual is exposed WHO declared Covid-19 a pandemic on March 11, 2020 which leads to stress anxiety burnout and need for sick leave which would harm the capacity of health care systems to provide services during crisis. Research approach in this study, quantitative research approach was found to be appropriate to assess 60 students from nursing college of IUST random sampling technique was used for selecting the sample pandemic related perceived stress scale was used for data collection.: The research design selected for this study was Descriptive Survey Design the current study was about to assess the level of stress among nursing students during Covid -19 pandemic. Hence, as per the nature of the research problem descriptive design was selected.The responses of the subjects to the standard tool revealed that most of the nursing students had moderate stress 75% (45) followed by high stress with 16.7% (10) and mild stress with 8.3% (5). The mean low stress was 1.40 (SD = .548, percentage = 8.3%), mean moderate stress 1.57 (SD = .503, percentage = 75%) and mean high stress was 1.57 (SD = .500, percentage = 16.7%).
Effect of exclusive breastfeeding up to 6 months on mortality of children due to pneumonia
Authors: Kamal Murtaza , Ansari Md Ehtesham , Choudhary Pallavi 
Published: March 2022

To observe the effect of exclusive breastfeeding up to 6 months in children in terms of mortality due to pneumonia. This was a hospital-based, prospective, observational study. Study was done in a tertiary care hospital. 300 children of both sexes between 2 months to 5 years of age were enrolled in this study according to WHO defined criteria for severe and very severe pneumonia. In the study, chances of getting very severe pneumonia was 4.1times more and mortality was 24.7% in the children who did not get exclusive breast feeding up to 6 months in comparison only 3.9% children died who had exclusive breastfeeding up to 6 months. Children who do not receive exclusive breastfeeding up to 6 months are more prone to have more severe pneumonia and relatively higher chance of mortality.
Rh incompatibilty: A case study
Authors: Kamei Almond , Warrior Mamta Anandini 
Published: March 2022

Rh incompatibility occurs during pregnancy. Rh antibodies cross the placenta and attack the baby's red blood cells leading to Hemolytic anemia. With Rh incompatibility, the woman's immune system reacts and creates Rh antibodies. Rh incompatibility happens only when the father of the baby is Rh-positive. Difference in blood type between a pregnant woman and her child causes Rh incompatibility. Nurse plays a vital role to offer psychological support to the mother and also to the members of the family.
Clinical, Laboratory Characteristic, and Treatment of Human Toxocariasis in Northern Vietnam
Authors: Nguyen Thu Huong , Van Thang Dao , Thi Anh Van Nguyen , Huy Tho Tran , Trung Tuyen Nguyen , Van Nam Le , Nhu Binh Do 
Published: March 2022

Background: We determined the occurrence frequency of Clinical signs, subclinical characteristics on positive anti-IgG Toxocara ELISA cases, and clinical response results after 1 month of albendazole-specific treatment.
Methods: A number of 103 clinically treated patients were studied between 2018 and 2019 in two hospitals. Relevant data are collected from examination and medical records such as age, sex, job, resident, clinical and sub-clinical signs. Sera samples were subjected to anti-IgG Toxocara antigen using ELISA.
Results: The median age of the patient was 43.6 ± 14.4 years. The most common symptom groups were the skin and mucosa (88.3%), followed by neurological symptoms (44%). There are 76.7% of patients with risk factors for contact with pet dogs and cats. The majority of eosinophils in the normal range (< 8%) accounted for 85.4%, the major results of the OD value of ELISA were in the group (≥ 0.3-< 1.5) accounted for 75.7%. The skin and mucosa lesions in toxocariasis patients related to IgE values were statistically significant (P <0.05). The effectiveness of anthelmintic treatment is low with nearly half of patients having no clinical symptoms after 1 month of post-treatment. It is statistically significant between exposure to dogs/cats and treatment outcomes on clinical symptoms (P < 0.05).
Conclusion: Toxocara infections in Vietnamese people often have skin allergies and liver damage, rarely with severe neurological symptoms. The efficacy of albendazole treatment after one month is not clear. In the near future, research with a confirmatory test other than Anti-IgG Toxocara ELISA is needed to screen for in-hospital diagnosis.
PENERAPAN METODE EKSPONENTIAL SMOOTHING DALAM MEMPREDIKSI JUMLAH PESERTA DIDIK BARU DI SMA FAVORIT KOTA PAYAKUMBUH
Authors: Marizal Muhammad , Mutiarani Fikha 
Published: March 2022

Forecasting is a technique for estimating a value on a particular object in the future by paying attention to past data. This forecasting uses the Exponential Smoothing models because the data used is in accordance with the model. This study aims to predict the number of students in favorite high schools in Payakumbuh based on data obtained from 2014 until 2021 which is grouped into science and social studies classes. Forecasting is done using a Single Exponential Smoothing and Double Exponential models. MAPE results show that the Double Exponential Smoothing model is better at predicting the number of new students than Single Exponential Smoothing. Keywords: Double exponential smoothing, forecasting, single exponential smoothingMSC2020: 62M10
Update on the Clinical Trials Landscape: Analysis of ClinicalTrials.gov Registration Data: 2000-2020
Authors: Gresham Gillian , Gresham Arthur G , Meinert Jill L , Piantadosi Steven , Meinert Curtis L 
Published: March 2022

Abstract
Background: The clinical trials landscape has evolved over the last two decades, shaped by advances in therapeutics and drug development, the emerging role of technology in trials, innovation in trial design and methods, and increased access to clinical trial information and data through registration. The ClinicalTrials.gov website was launched in 2000 by the NIH National Library of Medicine and is the largest clinical trials registry worldwide. The purpose of this cross-sectional analysis is to describe the composition and methodologic features of clinical trials as registered on ClinicalTrials.gov, and to identify key trends over time. Methods: We analyzed data from the publicly available CTTI AACT database, focusing on trials (interventional studies) started between 1 January, 2000 through 31 December, 2020. Characteristics of trial design (e.g., randomization, use of masking, sample size), eligibility criteria, outcome types, interventions, conditions, and results reporting were summarized over time. Results: There were 271,272 trials included in the analysis, of which 57% were completed. Most trials were randomized (66%), single site (68.7%), funded by other sources (69.0%) and had sample sizes less than 100 participants (62%). There was a significant increase in trials without FDA-defined phases ("Phase N/A") observed over time as a result of evolving trial designs, interventions and outcome types. Over 3,000 trials related to COVID-19 started in 2020 alone. Conclusions: ClinicalTrials.gov is a powerful tool that provides a window into the past, present, and future of the clinical research enterprise. Understanding characteristics and trends of trials can inform future trial design and clinical decision making.
Investigation of a Novel Ultrasonically Aided Electrochemical Magnetic Abrasive Machining Process for SS 316L
Authors: Farwaha Harnam Singh , Deepak Dharmpal , Brar Gurinder Singh 
Published: March 2022

Abstract
Many present day applications require machining and finishing of complex shaped and tough to machine materials with precision and accuracy by conventional or non-conventional machining and polishing processes. Ultrasonically aided electrochemical magnetic abrasive machining (UAEMAM) process is a novel non-conventional machining technique which can machine and finish the product for better surface quality. In present research work, the development and performance evaluation of UAEMAM process for machining of SS 316L is reported. The UAEMAM process is optimised using response surface methodology (RSM) based on central composite design (CCD) and grey relational analysis. The main machining variables such as work piece rotational speed, working gap, concentration of NaNO 3 , percentage of abrasives by weight and pulse on time were chosen to determine percentage improvement in surface finish improvement (PISF) and material removal rate (MRR) in the UAEMAM process. The significant machining factors and the best combination levels of machining parameters associated with PISF and MRR were determined. The benefits of ultrasonic aided electrochemical magnetic abrasive machining were also confirmed from the micrograph observations of the surface. Experimental results show that UAEMAM process is effective for machining and polishing components for better surface finish.
Phenological changes and effects of Populus euphratica under the background of climate change
Authors: zhao chunyan , He xiaohui , Qin Jie , Zhou Dong Meng 
Published: March 2022

Abstract
Phenology is a key indicator of climate change. We studied the phenological change of Populus euphratica during 1960–2019, and investigated the relationships between phenological change and climate change. The results showed that the annual average temperature in the Lower reaches of Heihe River was increased significantly over the past 58years, which directly led to the germination of Populus euphratica was advanced, and the leaf yellowing delayed. The growth season of Populus euphratica was significantly prolonged after 1990, and the mean growth season length were 230, 236, 245 days in 1960–1969,1990–1999,2010–2019, respectively. Temperature is the major environmental factor affecting phenological change, and the length of growing season was prolonged with the increase of annual average temperature and accumulated temperature. Phenological changes have an important effect on plant growth. Our study showed that the frost days of Populus euphratica increasing from 1990 to 2019, and the frost days was increased with the growth season length. The accumulated frost days were 19, 21, 23 days in 1990–1999, 2000–2009, 2009–2019. Our studies also indicated that phenological changes also affect socioeconomic, especially the delay of leaf yellow period maybe has an important impact on tourism due to the best viewing period is postponed. Our study of phenological change law and its relationships with climate changes could guide the government formulates tourism policies and help tourists to arrange best viewing time.
Whole-Exome Sequencing Identified Mutational Profiles of Urothelial Carcinoma post Kidney Transplantation
Authors: Lim Lee-Moay , Chung Wen-Yu , Hwang Daw-Yang , Yu Chih-Chuan , Ke Hung-Lung , Liang Peir-In , Lin Ting-Wei , Huang A-Mei , Kuo Hung-Tien 
Published: March 2022

Abstract
Background: Kidney transplantation is a lifesaving option of selected patients with end-stage kidney disease (ESKD). Urothelial carcinoma (UC) is the most common de novo cancer after kidney transplantation in Taiwan. UC has the characteristics of high mutational burden and elevated degree of molecular heterogeneity compared with other solid tumors. However, there are limited research exploring the genomic alterations in UC after kidney transplantation. Methods: In this study, we performed whole exome sequencing (WES) to compare the genetic alterations between UC developed after kidney transplantation (UCKT) and UC from hemodialysis patients (UCHD). After mapping and variant calling, a total of 18,733 and 11,093 mutations were identified from UCKT and UCHD patients, respectively. We first excluded known SNPs and then retained genes that were annotated in Cosmic, Intogen, and TCGA bladder databases for onco-driver genes. Seventeen UCKT unique genes with recurrent SNPs in more than two patients were subjected for further analysis. IPA pathway analysis was used to explore the interconnections among these genes. Results: 17 novel mutations of BTK, CARD11, ELL, FNBP1, GNAQ, HOXD13, IKZF1, MAX, MLLT10, NTRK3, PAX5, SEPTIN6, SEPTIN9, SH3GL1, SLC34A2, TAL1 , and TRAF7 were identified UCKT groups, and none of the genes had been reported in the genomes of patients with UC. Among the affected genes, GNAQ, IKZF1, and NTRK3 were potentially involved in the signaling network of UCKT. Conclusion : Our findings provide information for understanding the mutational landscape of UC developed after kidney transplantation, and a gene list that may be of great importance in related molecular mechanisms. Genetic analysis in malignancy after transplantation may help to identify high risk patients in post-transplant care and also illuminate a fundamental aspect of the molecular pathogenesis of post-transplantation UC.
Impact of untethering of the spinal cord on urological management and antibiotic stewardship among spina bifida patients in Malaysia
Authors: Nisheljeet Singh , Azizi Abu Bakar , Palaniandy Kamalanathan , Ganesan Dharmendra , Ong Teng-Aik , Alias Azmi , Rajamanickam Ramalinggam , Atroosh Wahib Mohammed , Mohd-Zin Siti Waheeda , Lee-Shamsuddin Andrea , Nivrenjeet Singh , Abdul-Aziz Noraishah Mydin 
Published: March 2022

Abstract
Background
The incidence and severity of urinary tract infections (UTIs) due to spina bifida is poorly understood in Malaysia. Tethering of the spinal cord is a pathological fixation of the cord in the vertebral column that can result in neurogenic bladder dysfunction and other neurological problems. It occurs in patients with spina bifida and the authors of this study sought to determine the effects of untethering on the urological outcome of children with a tethered cord and thus identifying proper urological management for individuals with spina bifida.
Methods
Demographic and clinical data were collected via an online questionnaire and convenient sampling technique were used. 49 spina bifida individuals participated in this study.
Results
The diagnosis of UTIs is dependent on patients reporting cloudy and smelly urine (67%) and urine validation (60%). 18% of the respondents claimed to have been prescribed antibiotics even though they had no history of UTI. Indiscriminate prescription of antibiotics by healthcare workers further compounds the severity of UTI. Employing CISC (73%) including stringent usage of sterile catheters (71%) did not prevent patients from getting UTI. Overall, 33% of our respondents reported manageable control of UTI (0 – 35 years of age). All individuals below the age of 5 (n=14) had improved urological outcome due to the untethering surgery under the guidance of the Malaysia NTD support group.
Conclusion
Spina biﬁda individuals may procure healthy bladder and bowel continence for the rest of their lives provided that neurosurgical and urological treatment being instigated soon after birth and continuing into adulthood.