bluuebunny/crossref_metadata_2025_split huggingface dataset:
High platelet distribution width can independently predict testicular survival in testicular torsion among patients with steady-state sickle cell anemia
Authors: Adawi Essa A , Ghanem Mazen Ahmed , Ghanem Ahmed Mazen , Safan Manal A , Elsayed Mohamed G , Aqeel Mohammed A 
Published: January 2022

ObjectiveThis study aimed to evaluate the predictive value of platelet volume indices (PVI), such as mean platelet volume (MPV), platelet distribution width (PDW), and plateletcrit (PCT), as prognostic indicators of testicular viability in torsion patients with steady-state sickle cell anemia (SCA) who underwent surgical exploration.MethodsForty-eight patients with SCA with testicular torsion and 46 male control subjects were enrolled in the study. All patients underwent scrotal color Doppler ultrasonography before surgery, and PVI (MPV, PDW, and PCT) values were measured in all participants. Symptom duration and testicular volume were also recorded.ResultsThe testicular salvage rate in patients with SCA was 73% after surgery. Analyses showed that MPV, PDW, and PCT values were significantly higher in torsed SCA as compared with controls (p<0.05). Orchiectomy in patients with SCA showed significantly higher MPV, PDW, and PCT values than the orchiopexy group (p<0.05). The MPV values of orchiectomy patients showed a higher significant cut-off of ≥11.5 fL, which is higher than in torsed patients without SCA, as an indicator of testis survival. PDW also demonstrated a higher significant cut-off of ≥12.7 fL for detorsion outcomes in patients with SCA. Symptom duration of less than 7 hours was also significantly correlated with orchiopexy (p≤0.001). Univariate analysis showed that higher MPV, increased PDW, and symptom duration were indicative of the outcome of testicular detorsion in SCA. Multivariable analysis showed that increased PDW and symptom duration are prognostic parameters for testicular viability in SCA.ConclusionIncreased PDW and symptom duration can be used as parameters for predicting testicular detorsion outcomes in patients with steady-state SCA.
Diagrama ou dispositivo? Foucault entre Deleuze e Agamben
Authors: Agostinho Larissa Drigo 
Published: January 2022

O objetivo desde texto é resgatar a noção de diagrama presente em Foucault para diferenciar duas interpretações do conceito de dispositivo, a leitura de Agamben e a leitura que Deleuze faz de Foucault. A noção de dispositivo de Agamben diz respeito às positividades concretas que se inserem numa rede de poder. Pretendemos demonstrar que o conceito de Deleuze não deixa de lado outros aspectos do conceito foucaultiano, o dispositivo ou diagrama além de ser uma rede entre diversos elementos discursivos e não discursivos, é também mais geral que uma episteme, neste sentido ele contém elementos que não são totalmente capturados pelo poder, forças que não se deixam materializar em aparelhos de controle, sujeitos que não se deixam sujeitar ou que escapam das teias do poder.
Provar algo não significa convencer o público: lições de pensadoras ‘feministas’ do século XVII
Authors: Zirbel Ilze 
Published: January 2022

O presente artigo traz algumas reflexões da filósofa e feminista decolonial Elsa Dorlin sobre o que chamou de feminismo-lógico-filosófico do século XVII, presente nas posições de Marie de Gournay, Anna Maria Van Schurman, François Poullain de la Barre e Gabrielle Suchon. Neste artigo, esse tipo de filosofia é classificado como lógico-igualitarista e recebe uma quinta representante: Mary Astell. Estas filósofas e la Barre defenderam uma igualdade entre os ‘sexos' por meio de argumentos lógicos que visavam demonstrar a igualdade como algo verdadeiro e irrefutável. É nossa intenção apresentar ao público brasileiro algumas das estratégias utilizadas por essas filósofas, e apontadas por Dorlin, no debate sobre a desigualdade ou igualdade entre os sexos. Por fim, focaremos nos motivos pelos quais as estratégias utilizadas não chegaram a atingir seu objetivo: um contexto de juízos e juízes corrompidos.
Interações, espaços e ambientes utilizados por entendidas belorizontinas: um caminho velado
Authors: Souza Janice Aparecida de , Chacham Alessandra Sampaio 
Published: January 2022

Este artigo aborda a invisibilidade da homossexualidade feminina a partir da análise da experiência de uma “Confraria” de Lésbicas mineiras nascidas na década de 1950. O objetivo é refletir sobre os usos que faziam dos espaços e sobre as interações possíveis à época. Se é a partir dos processos de interação social que o sentido e o significado nas relações emergem, a forma pela qual a cidade acolhe ou ignora e invisibiliza determinados sujeitos impacta suas vidas. O modo pelo qual elas se apropriaram dos espaços disponíveis na cidade de Belo Horizonte e a criação de outros espaços mais reservados foram fundamentais para a criação de longevos vínculos de amizade e convivência. Tais vínculos parecem ter colaborado para uma rede de apoio mais estruturada na velhice formada por relações de afeto, amizade e solidariedade.
Language Contact, Cognition, and Cross-Linguistic Influence in the Greek Pentateuch
Authors: Maurais Jean 
Published: January 2022

Abstract
This study engages recent discussions concerning the description of the Greek of the LXX Pentateuch and the nature of source text interference. Research in contact linguistics and cognition provides a framework to describe the various phenomena observed, ranging from borrowing of linguistic material to the more widespread structural transfer. Processes such as pivot-matching and the cognitive aspects of word-choice transfer shed light on the mechanics of translation and issues such as the nature of cross-linguistic influence and a translator’s apparent inconsistencies. In this context, the intelligibility of specific renderings or their grammatical conventionality are not sufficient criteria for assessing cross-linguistic influence since its effects can be felt at the level of register or genre. This has important ramifications for the register or genre categorization of various textual units of the LXX Pentateuch and stylistic descriptions.
Who Owned Florence?: Religious Institutions and Property Ownership in the Early Modern City
Authors: Walden Justine , Terpstra Nicholas 
Published: January 2022

Abstract
This study employs a 1561 tax census to survey estimated property incomes in Florence with particular attention to lay and ecclesiastical religious institutions. Its key findings are five. First, religious institutions were collectively the wealthiest corporate entities in the city, holding one fifth of all residential properties and one third of all workshops, and drawing 20.2 percent of all property income generated within city walls. Second, many were civic- and lay-religious institutions such as confraternities and hospitals. Third, the property income of religious houses was distributed across multiple organizations while that held by the Florentine diocese was concentrated in a few. Fourth, among religious orders, Mendicant houses had a larger urban presence than the older contemplative houses. Fifth, the property holdings of the formally defunct military-religious order of the Knights of S. Jacopo signal the deftness with which some institutions adapted to new circumstances. Overall, this survey of property incomes helps quantify the shape of power in the Florentine religious universe.
Impacts of Rotation Axis and Frequency on Vestibular Perceptual Thresholds
Authors: Wagner Andrew R. , Kobel Megan J. , Merfeld Daniel M. 
Published: January 2022

Abstract
In an effort to characterize the factors influencing the perception of self-motion rotational cues, vestibular self-motion perceptual thresholds were measured in 14 subjects for rotations in the roll and pitch planes, as well as in the planes aligned with the anatomic orientation of the vertical semicircular canals (i.e., left anterior, right posterior; LARP, and right anterior, left posterior; RALP). To determine the multisensory influence of concurrent otolith cues, within each plane of motion, thresholds were measured at four discrete frequencies for rotations about earth-horizontal (i.e., tilts; EH) and earth-vertical axes (i.e., head positioned in the plane of the rotation; EV). We found that the perception of rotations, stimulating primarily the vertical canals, was consistent with the behavior of a high-pass filter for all planes of motion, with velocity thresholds increasing at lower frequencies of rotation. In contrast, tilt (i.e, EH rotation) velocity thresholds, stimulating both the canals and otoliths (i.e., multisensory integration), decreased at lower frequencies and were significantly lower than earth-vertical rotation thresholds at each frequency below 2 Hz. These data suggest that multisensory integration of otolithic gravity cues with semicircular canal rotation cues enhances perceptual precision for tilt motions at frequencies below 2 Hz. We also showed that rotation thresholds, at least partially, were dependent on the orientation of the rotation plane relative to the anatomical alignment of the vertical canals. Collectively these data provide the first comprehensive report of how frequency and axis of rotation influence perception of rotational self-motion cues stimulating the vertical canals.
Case–Control Study on Exercise-Induced Vasculitis in Hikers
Authors: Quéneau Alexandre , Pistorius Marc-Antoine , Connault Jérôme , Raimbeau Alizée , Gautier Giovanni , Bergère Guillaume , Artifoni Mathieu , Durant Cécile , Bénichou Antoine , Hersant Jeanne , Espitia Olivier 
Published: January 2022

The aim of this study was to identify clinical factors associated with exercise-induced vasculitis (EIV). This study included EIV cases and controls matched for age. Cases included were all members of a hiking club and participated in extended hiking trips. Exercise-induced vasculitis was diagnosed based on clinical signs occurring only after prolonged walks. Chronic venous disease was defined using the Clinical Etiological Anatomical Pathophysiologic classification. This study included 162 hikers: 32 EIV cases and 130 matched controls. Mean age at EIV diagnosis was 47.1 years and 24 (75.0%) of EIV cases were women. Chronic venous disease was present in 19 (57.6%) of EIV cases vs 39 (30.0%) in controls ( P = .001); those with EIV had significantly more saphenous vein insufficiency and C3 venous insufficiency than controls, 85.0 vs 52.6% and 8 (25.0%) vs 13 (10.0%) ( P = .02), respectively. For EIV cases, mean walking distance per hike was significantly higher than for controls ( P = .002). Exercise-induced vasculitis symptoms were typical with rash and/or purpura on the leg in warm conditions. Lesions spontaneously disappear in <10 days. In this study, EIV cases had more chronic venous disease and longer mean walking distances than controls.
A Randomized Controlled Trial of Repetitive Peripheral Magnetic Stimulation applied in Early Subacute Stroke: Effects on Severe Upper-limb Impairment
Authors: Jiang Yi-Fan , Zhang Dai , Zhang Jing , Hai Hong , Zhao Ying-Yu , Ma Yue-Wen 
Published: January 2022

Objectives Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive method that activates peripheral nerves and enhances muscle strength. This study aimed to investigate the effect of rPMS applied in early subacute stroke on severe upper extremity impairment. Design Randomized controlled trial. Setting Rehabilitation department of a university hospital. Subjects People aged 30–80 years with no practical arm function within four weeks of a first stroke. Interventions Participants were randomly assigned to either the rPMS group ( n = 24, 20Hz and 2400 pulses of rPMS to triceps brachii and extensor digitorum muscles daily for two weeks in addition to conventional physiotherapy) or the control group ( n = 20, conventional physiotherapy). Main measures The primary outcome was the upper extremity motor section of Fugl-Meyer Assessment after treatment. Secondary outcomes included Barthel Index and root mean square of surface electromyography for muscle strength and stretch-induced spasticity of critical muscles of the upper extremity. Data presented: mean (SD) or median (IQR). Results The rPMS group showed more significant improvements in the Fugl-Meyer Assessment (12.5 (2.5) vs. 7.0 (1.4), P < 0.001), Barthel Index (15 (5) vs. 10 (3.7), P < 0.001), and strength-root mean square (biceps brachii: 20.5 (4.8) vs. 6.2 (2.7), p < 0.001; triceps brachii: 14.9 (5.8) vs. 4.3 (1.2), p < 0.001; flexor digitorum: 5.1 (0.8) vs. 4.0 (1.1), p < 0.001) compared with the control group. Conclusion In patients with no functional arm movement, rPMS of upper limb extensors improves arm function and muscle strength for grip and elbow flexion and extension.
Lifetime use of MDMA/ecstasy and psilocybin is associated with reduced odds of major depressive episodes
Authors: Jones Grant M , Nock Matthew K 
Published: January 2022

Background: Depression is a major mental health issue worldwide, with high rates of chronicity and non-recovery associated with the condition. Existing treatments such as antidepressant medication and psychological treatments have modest effectiveness, suggesting the need for alternative interventions. Aim: The aim of this study was to examine the relationships between MDMA (3,4-methylenedioxymethamphetamine)/ecstasy and psilocybin use and major depressive episodes (MDEs). Methods: This observational study used data from a large ( N = 213,437) nationally representative sample of US adults to test the association of lifetime use of MDMA/ecstasy, psilocybin and other classic psychedelics (lysergic acid diethylamide (LSD), peyote, mescaline), other illegal substances (e.g. cocaine, phencyclidine (PCP)), and legal/medicinal substances of misuse (e.g. pain relievers, tranquilizers) with lifetime, past year, and past year severe MDEs. Results: Results revealed that lifetime MDMA/ecstasy use was associated with significantly lowered odds of a lifetime MDE (adjusted odds ratio (aOR) = 0.84; p < 0.001), past year MDE (aOR = 0.84; p < 0.001), and past year severe MDE (aOR = 0.82; p < 0.001). Psilocybin was associated with significantly lowered odds of a past year MDE (aOR = 0.90; p < 0.05) and past year severe MDE (aOR = 0.87; p < 0.05). All other substances either shared no relationship with a MDE or conferred increased odds of an MDE. Conclusions: These results suggest that MDMA/ecstasy and psilocybin use is associated with lower risk of depression. Experimental studies are needed to test whether there is a causal association between use of these compounds and the alleviation of depressive symptoms.
Is Oral Contrast Beneficial for Visualization of the Appendix in Low-Weight Children?
Authors: Shapira-Zaltsberg Gali , Dien Esquivel Maria , Mitsakakis Nicholas , Hayawi Lamia , Miller Elka 
Published: January 2022

Purpose: It has been shown that oral contrast does not improve the diagnostic accuracy of Computed Tomography (CT) for appendicitis in pediatric patients; however, the cohorts in these studies were not stratified by weight or body mass index. The purpose of this study is to assess the benefit of oral contrast administration for identifying the appendix in younger children in the lower weight quartile. Materials and Methods: This retrospective study comprised 100 patients (2–10 years) in lower weight quartile who had intravenous contrast-enhanced CT of the abdomen and pelvis, 37 of which with oral contrast, and 63 without. A pediatric radiologist and a pediatric radiology fellow independently assessed whether the appendix was visualized or not. In case of discrepancy, an additional pediatric radiologist was the “tie-breaker.” Chi-squared test was used to compare the proportion of visualized appendix between the groups (with and without oral contrast). Inter-rater reliability was determined using Cohen’s Kappa coefficient. Results: There was no significant difference in the visualization of the appendix between the group with oral contrast and without ( P = 1). The Cohen Kappa coefficients were .33 (.05, .62) and .91 (.73, 1.00) for the “no oral” and “oral” groups, respectively, yielding evidence of a difference ( P = .007). Conclusions: There was no significant difference in the visualization of the appendix using CT with or without oral contrast in low-weight pediatric patients. The inter-rater reliability, however, was significantly higher in the group given oral contrast. Additional studies assessing the value of oral contrast for the sole indication of appendicitis may provide clearer results.
Masking for School-Age Children With Epilepsy: We Do Have Consensus!
Authors: Fine Anthony L. , Wong-Kisiel Lily C. , Nickels Katherine C. , Wirrell Elaine C. 
Published: January 2022

Introduction This study was designed to assess current recommendations from child neurologists and epileptologists on masking for school-age children with epilepsy. Methods A 7-item survey was created and sent out to members of the Child Neurology Society and Pediatric Epilepsy Research Consortium in August of 2021 to assess current practice and provider recommendations on masking. Results One hundred four individuals participated with representation from all regions of the United States. Masking was recommended by 95.1%, with 63.4% (n = 66) noting exception of those with severe intellectual disability, autism, and behavioral problems. Of those who write exemption letters, 54% write these <5% of the time. Only 3% reported potential adverse events associated with masking. Conclusion Nearly all respondents recommended masking for school-age children with epilepsy. Potential risks of masking and adverse events were low. Improved guidance on masking is needed to ensure academic success of our patients with epilepsy.
Can Women Shelters Help Reduce Symptoms of PTSD and C-PTSD? Trajectories of PTSD Symptom Development Following Partner- and Family-Related Violence
Authors: Dokkedahl Sarah , Kristensen Trine Rønde , Elklit Ask 
Published: January 2022

Background: To protect women from Intimate partner violence (IPV), women’s shelters should not only provide emergency safety from IPV exposure, but also prolonged support that empowers women to build a life free from violence. The present study aims to investigate individual symptom development in association with residency at a women’s shelter. Method: Data were collected at four different timepoints, that is, enrolment (T1, N = 150), 3-months residency (T2, = 110), 6-months residency (T3, N = 68) and after relocation (T4, N = 63). Women were included from four Danish women’s shelters. The International Trauma Questionnaire (ITQ) was applied to test for post-traumatic stress disorder (PTSD) and Complex-PTSD (C-PTSD) at all timepoints. A paired sample t-test was used to test the mean symptom development, and a Latent Class Growth Analysis (LCGA) was applied to test for different classes of PTSD-trajectories. Logistic regression was applied to predict class membership from shelter-related variables and symptom severity, that is, length of residency, psychological counselling, revictimization and key symptoms of C-PTSD. Results: The prevalence of PTSD (31%) and C-PTSD (37.9%) was high at enrolment. Although t-tests suggested a significant decline in symptoms at follow-up, the LCGA revealed different classes of symptom development. The two-class model was found to be the best representation of data with low-symptom- and high-symptom profiles, respectively. Overall, the largest decline in symptoms occurred within the first 3 months of residency. Revictimization was high and was further found to predict class membership. However, when included in a multiple regression only symptom severity predicted the high-symptoms profile class. Discussion: Psychological treatment focussing on PTSD and C-PTSD is important for the women’s future well-being and safety. Reports on revictimization was alarmingly high, which emphasises a continuing need to protect women from psychological violence within the shelters. These findings should be replicated in larger samples before we can draw any conclusion.
Metabolic syndrome predicts new damage in systemic lupus erythematosus patients: Data from the Almenara Lupus Cohort
Authors: Elera-Fitzcarrald Claudia , Reatégui-Sokolova Cristina , Gamboa-Cárdenas Rocío V , Medina Mariela , Zevallos Francisco , Pimentel-Quiroz Victor R , Cucho-Venegas Jorge M , Alfaro-Lozano José L , Rodriguez-Bellido Zoila , Pastor-Asurza Cesar A , Perich-Campos Risto , Alarcón Graciela S , Ugarte-Gil Manuel F 
Published: January 2022

Objectives This study aims to determine whether the MetS predicts damage accrual in SLE patients. Methods This longitudinal study was conducted in a cohort of consecutive SLE patients seen since 2012 at one single Peruvian institution. Patients had a baseline visit and then follow-up visits every 6 months. Patients with ≥ 2 visits were included. Evaluations included interview, medical records review, physical examination, and laboratory tests. Damage accrual was ascertained with the SLICC/ACR damage index (SDI) and disease activity with the SLEDAI-2K. Univariable and multivariable Cox-regression survival models were carried out to determine the risk of developing new damage. The multivariable model was adjusted for age at diagnosis; disease duration; socioeconomic status; SLEDAI; baseline SDI; the Charlson Comorbidity Index; daily dose; and time of exposure of prednisone (PDN), antimalarials, and immunosuppressive drugs. Results Two hundred and forty-nine patients were evaluated; 232 of them were women (93.2%). Their mean (SD) age at diagnosis was 35.8 (13.1) years; nearly all patients were Mestizo. Disease duration was 7.4 (6.6) years. The SLEDAI-2K was 5.2 (4.3) and the SDI, 0.9 (1.3). One hundred and eight patients (43.4%) had MetS at baseline. During follow-up, 116 (46.6%) patients accrued at least one new point in the SDI damage index. In multivariable analyses, the presence of MetS was a predictor of the development of new damage (HR: 1.54 (1.05–2.26); p < 0.029). Conclusions The presence of MetS predicts the development of new damage in SLE patients, despite other well-known risk factors for such occurrence.
Validation of the Digital Eye Strain Questionnaire and pilot application to online gaming addicts
Authors: Mylona Ioanna , Glynatsis Mikes N. , Dermenoudi Maria , Glynatsis Nikolaos M. , Floros Georgios D 
Published: January 2022

Introduction ‘Digital eye strain’ (DES) is a clinical syndrome with eyesight symptoms related to continuous engagement in front of a screen-enabled digital device. With use of these devices constantly on the rise, the related symptoms have become prominent, even in younger ages. This study describes the process of validating the Digital Eye Strain Questionnaire (DESQ), a thirteen-item self-report scale in a yes-no format designed to offer a measure of complaints related to digital eye strain syndrome (DES). Methods The validation process included 150 outpatients with no long-standing eye disease who were examined for various eye complaints and 50 outpatients who were diagnosed with gaming addiction according to WHO ICD-11 clinical criteria. All participants filled in a demographics questionnaire, the DESQ, the Computer Vision Syndrome Questionnaire (CVS-Q) and the Problematic Internet Use Questionnaire-9 (PIUQ-9). Results Principal component analysis of categorical variables confirmed the proposed three-factor DES structure with a total of 61.02% of explained variance and Cronbach's alpha equal to.94. Concurrent validity was assessed by comparing the results of the DESQ to the CVS-Q while convergent validity was assessed by examining correlations of the DESQ with results from the PIUQ-9 questionnaire. In all cases the DESQ demonstrated excellent reliability and validity. Conclusions Results indicate that the DESQ questionnaire can be employed to reliably measure the symptomatology of digital eye strain in clinical populations who present either with eye issues or with excessive use of the gaming and screen-enabled devices in general.