bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lung Stereotactic Radiation Therapy: Intercomparison of Several Irradiation Devices in Terms of Outcome and Predictive Factors
Authors: Reun Eymeric Le , Casutt Alessio , Durham André , Bouchaab Hasna , Romano Edouard , Lovis Alban , Krueger Thorsten , Von Garnier Christophe , Ozsahin Esat-Mahmut , Kinj Rémy 
Published: January 2022

Abstract
Background: Stereotactic body radiotherapy (SBRT) is recommended for the treatment of inoperable early stage non-small-cell lung cancer and lung oligometastases. The radiation oncology department of the Lausanne University Hospital (CHUV) gathers three different radiotherapy devices able to treat pulmonary lesions in SBRT conditions: CyberKnife® (CK), Helical Tomotherapy® (HT), and volumetric modulated arc therapy (VMAT). The aim of this study is to define the patients’ outcome in terms of irradiation efficacy and toxicities after lung SBRT depending of the choice of the SBRT technique.Methods: We retrospectively analyzed the clinical, radiological, and dosimetric data of patients with primary lung tumor or pulmonary oligometastases treated with SBRT between January 2016 and February 2020. We analyzed descriptive data using the Chi-2 test for proportions and the T-test for means comparisons, survival data by the Kaplan-Meier method and comparisons between groups by the Log-rank test and Cox-regression.Results: We identified 111 patients mostly in good condition (82.9% PS 0-1) with a median age of 71.4 years. One hundred forty-two lesions were treated with a typical fractionation of 55 Gy in 5 fractions, delivered by CK (59.9%), VMAT (38.0%), or HT (2.1%). Compared to other techniques, CK technique allowed to treat comparable gross tumor volume (GTV; 2.1 vs 1.4cc, p = 0.84) with smaller planning treatment volume (PTV; 12.3 vs 21.9 cc, p = 0.013), and was associated with a lower mean lung dose (MLD; 2.6 vs 4.1 Gy, p < 0.001), a lower V5 (13.5 vs 19.9 cc, p = 0.002) and a lower V20 (2.3 vs 5.4 cc, p < 0.001). Local control rates at 2 years were not different depending on the irradiation device, respectively of 96.2% (range, 90.8-100) and 98.1% (range, 94.4-100), p = 0.68. Toxicity incidence was significantly increased with V5 value > 17.2% (56.0 vs 77.4%, p = 0.021). Conclusions: Compared to other SBRT techniques, CK treatments permitted to treat comparable GTV with reduced PTV, MLD, V20, and V5. The dosimetric benefit of CK SBRT was not associated with a clear clinical benefit, with comparable outcome in terms of control rates and toxicity. Toxicity incidence was less frequent when reducing the V5. The use of CK is particularly attractive in case of multiple courses of lung SBRT or in case of local relapse requiring lung re-irradiation.Trial registration: Registered on February 24th 2021, ID 2021-00267, with the authorization of the CER-VD ethics committee (Switzerland).
Study on Hydrogenation Performance of Oil-Soluble Molybdenum Catalyst in Coal-Oil Co-Processing
Authors: Wang Guangyao , Wang Xiqian , Zhao Yuan 
Published: January 2022

Abstract
An oil-soluble molybdenum catalyst was synthesized by a simple and novel method and studied for hydrogenation in coal-oil co-processing. The catalyst was characterized by infrared spectrum (IR), thermogravimetry (TG), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS). The morphology and crystal structure of catalyst was characterized with scanning electron microscope (SEM) and high resolution transmission electron microscopy (HRTEM). The catalyst can be considered as a precursor that can be converted into active MoS2 components through thermal decomposition and sulfidation. The hydrogenation experiment was carried out by the model reactants of tetradecane and 2-methylnaphthalene with a change of reaction (405℃-445℃) temperature and concentrations of molybdenum catalyst (Mo conc. 0.6-10 mg/g), and results showed that the delightly hydrogenation function of catalyst is to improve the saturation of aromatic ring. The most abundant stacking numbers of decomposed catalyst were 2 and 3, accounting for 53% of all catalyst microcrystalline units. The rapid hydrogenation stage and the significant decrease of feed heavy fraction in co-processing experiment provided the evidence that the hydrogenation performance of the synthesized catalyst is remarkable in coal-oil co-processing.
Are People with Poor Differentiation of Self at Risk of Developing Eating Disorders? A Study of Jewish and Arab Participants
Authors: Peleg Ora , Tzischinsky Orna 
Published: January 2022

Abstract
Purpose: In light of findings that Israeli Arabs report higher prevalence of eating disorders (EDs) than Israeli Jews and that higher rates of the risk of EDs have been reported by females than males, the first aim of this study was to further investigate the cultural and gender differences in differentiation of self (DoS) and risk of developing EDs among Israeli young adults. The second aim was to examine whether DoS is associated with the risk of EDs. Methods: Of the 859 participants (670 females, mean age 26.8), 440 were Jewish and 419 were Arab. Participants took the Eating Attitudes Test (EAT-26) and completed the Differentiation of Self-Revised (DSI-R) questionnaire.Results: Results revealed that Jewish participants had significantly lower diet, bulimia, and total EAT-26 scores than their Arab counterparts, while Jewish female participants had higher dieting and lower emotional cutoff scores than Jewish male participants. In addition, Jews who reported higher levels of risk of EDs showed higher levels of BMI, emotional reactivity, emotional cutoff, and fusion with others. Arabs who reported higher levels of risk of EDs reported higher levels of BMI and emotional cutoff and lower levels of I-position. Conclusion: People with high risk of EDs may have difficulty maintaining intimate family relationships. In distressing situations, they tend to disconnect rather than share with or gain support from significant others. In each culture, the risk of EDs increases for differently: among the Arab participants, when feelings and needs remain unexpressed; among the Jewish participants, even when they have symbiotic family relationships.Level of evidence: Level V, cross-sectional descriptive study
Evaluation of the Efficacy and Threshold of Serum Anti-mullerian Hormone (AMH) Levels for Diagnosis and Prediction of Polycystic Ovary Syndrome (PCOS) Among Indian Women.
Authors: Sumji Sajad , Bhat Abid , Rashid Aafia , wani Imtiyaz , Vasudevan Vishnu , Sehar Tajali , Ganie Mohd Ashraf 
Published: January 2022

Abstract
Purpose: PCOS women exhibit higher levels of AMH and has been proposed to add value to diagnosis of PCOS incase ambiguity. However, variable cutoffs of AHM for PCOS prediction have been reported. This study was designed to determine diagnostic threshold of serum AMH levels and its correlation with clinical, hormonal and ultrasonographic parameters among women with PCOS.Materials: In this prospective study, 113 women with PCOS as per Rotterdam criteria 2003 and 75 normo-ovulatory women were included. Clinical, biochemical, hormonal and sonographic assessment in addition to serum AMH levels were determined using standard methodology.Results: Mean age was comparable (23.43±3.42vs.24.21±3.18 years) between cases and controls. The mean number of menstrual cycles per year were lower while as mean BMI, FG score, and serum testosterone were higher in cases than controls (p<0.05). The mean serum AMH level was significantly higher in PCOS group (7.84±3.67vs. 3.23 ±1.56 ng/mL) than controls. The serum AMH levels showed a positive correlation(p<0.05) with LH/FSH ratio (r = 0.206, p = 0.029), number of ovarian follicles(r=0.461) and volume,(r=0.521), but no correlation significant with age and BMI. As per receiver operating characteristic (ROC) curve, cut-off was worked out to be 3.76 ng/mL with 86.7% sensitivity and 62.7% specificity. Conclusion: Serum AMH levels correlate positively with PCOM among PCOS women and may be a potent diagnostic marker of ovarian dysfunction either alone or in conjunction with other tools to ensure timely diagnosis and early treatment of the disorder.
Plant Growth-Promoting Bacteria Associated with the Nests of the Seed-Harvester Ant, Trichomyrmex Scabriceps
Authors: Kumari Pooja , Rastogi Neelkamal , Singh Harikesh Bahadur , Rajput Rahul Singh 
Published: January 2022

Abstract
Colonies of seed harvester ants are commonly found in semiarid and arid areas of the world and have been studied for their seed dispersal behaviour. The present study focused on the bacteria associated with the nests of the harvester ant, Trichomyrmex scabriceps, and reveals that ant colonies link the aboveground resources with the belowground microbial communities as they accumulate organic debris in the close vicinity of their nests via their ecosystem engineering activities. Soil samples were collected from the nest chambers and the external debris piles of T. scabriceps colonies, located in managed ecosystems. The nest soil-associated bacteria were examined for their plant growth-promoting abilities via biochemical assays including phosphate solubilization, Indole acetic acid production, siderophore production and physiological assays including biocontrol potential against the soil pathogen, Sclerotium rolfsii. More than 60% of bacteria isolated from the ant nest-associated soil displayed plant-growth promoting ability. Bacillus sp., Azotobacter sp., Klebsiella sp., Comamonas sp., Tsukamurella sp., and Pseudoxanthomonax sp., demonstrated significantly high levels of gnotobiotic growth of the treated chickpea plants. The activities of phenylalanine ammonia-lyase and peroxidase enzymes were higher in plant growth-promoting bacteria treated and pathogen inoculated plants as compared to the control plants lacking the bacteria. Since T. scabriceps colonies often make their nests in the compact soil of unpaved paths of agroecosystems and gardens, these bacteria can act as highly effective biofertilizers and promote growth of the cultivated plants by increasing soil fertility and disease resistance attributes of the plant.
Effect of Intake Manifold Geometry on Cylinder-to-Cylinder Variation and Tumble Enhancement in Gasoline Direct Injection Engine
Authors: Shin Jisoo , Kim Donghwan , Son Yousang , Park Sungwook 
Published: January 2022

Abstract
In order to improve the performance of the gasoline direct injection engine system, it is fundamentally important to reduce the cylinder-to-cylinder variation which affected by the intake manifold geometry. Furthermore, the early tumble development which influences the characteristics of the mixture as followed by the atomization and evaporation of the fuel, also greatly affects engine performance. Thus, in this study, the cylinder-to-cylinder variation in volumetric efficiency and tumble for two different type of intake manifold (curved type and straight type) was investigated using computational fluid dynamic program, CONVERE v2.4. And influence of the intake manifold curve radius to the early flow intensity and tumble development was analyzed. As a result, it was advantageous for cylinder-to-cylinder variation in the straight intake manifold compared to the curved intake manifold. When the intake manifold curve radius was increased in the straight intake manifold, it was effective in strengthening the early flow and tumble intensity. At 3000 rpm, the distance from the intake manifold inlet to the port also had an effect. Therefore, it is possible to improve the intake manifold performance by increasing the intake manifold curve radius and adapting turbocharging at engine speeds above 3000 rpm.
A Study on the Correlation Between M2 Macrophages and Regulatory T Cells in the Progression of Colorectal Cancer
Authors: Chen Yanlei , Gao Yu , Ma Xueqian , Wang Yanping , Liu Jinhao , Yang Chunyu , Bao Cuifen , Song Xiaoyu , Feng Yang , Sun Yan , Qiao Shifeng 
Published: January 2022

Abstract
Background: M2 macrophages and regulatory T cells (Tregs) can promote tumors and development by inhibiting the anti-tumor immune response. This study investigated the number of CD163‐positive M2 macrophages and Foxp3-positive Tregs in the progression of colorectal cancer. It also investigated the correlation and of M2 macrophages and Tregs.Methods: Postoperative tissue specimens and clinical data were collected from 197 patients with colorectal cancer who underwent initial surgical treatment in The Second Ward of Colorectal Surgery of the First Affiliated Hospital of Jinzhou Medical University from March 2020 to December 2020. Use immunohistochemical methods to detect the expression levels of CD163 protein-labeled M2 macrophages and Foxp3 protein-labeled Tregs in colorectal cancer tissues, matched paracancer tissues and lymph node tissues. Analyze the correlation between CD163 and Foxp3 in cancer tissues and lymph node tissues, as well as the relationship between clinicopathological characteristics and preoperative tumor markers. Results: M2 macrophages and Tregs were significantly positively correlated in cancer and lymph node tissues, which significantly increased in cancer and metastatic lymph node tissues. Interestingly, M2 macrophages in non-metastatic lymph nodes also increased significantly in patients with metastatic lymph nodes. Tregs stage I+II is higher than stage III+IV in paraneoplastic tissues. In addition, both CD163 and Foxp3 were upregulated with increasing tumor TNM stage, depth of infiltration, lymphatic metastasis, and depth of infiltration, and both were positively correlated with CEA. Conclusion: M2 macrophages and Tregs are important indicators of colorectal cancer progression and lymph node metastasis. There is a certain correlation between the two types of cells. It is possible that M2 macrophages, together with suppressor cells Tregs, promote an immunosuppressive environment.
Attempt TCP ACK-Storm Based Virtual Network Attacks and Defence Solutions
Authors: Khanh Tran Namm , Thanh Ta Minh 
Published: January 2022

Abstract
The rapid development of the digital age has been pushing people to access a mobile working environment when handsets are becoming more diverse and convenient with the help of Virtualization Technology. The speed and usability of Virtualization Technology are astounding for saving initial investment costs and optimizing IT infrastructure. Such Virtualization Technology is what businesses are interested in and makes the virtual server market growing strongly, especially for businesses that have many branches. However, virtual systems (hypervisors) are more vulnerable than traditional servers according due to many network attacks from curious users. Therefore, it's necessary to prepare for the worst circumstances, understand clearly, and research for new threats that can break down the virtual system. In this paper, we attempt to demonstrate the TCP ACK storm based DoS (Denial of Service) attack on virtual and Docker networks to show the threats that easily are happen on services deploying on virtual networks. Based on such consequence, we propose some solutions to prevent our virtual system from potential risks.
The Effect of Co-dependent (Thinking in Motion [tim]) Versus Single-modality (Cognifit) Interventions on Cognition and Gait Among Community Dwelling Older Adults With Cognitive Decline: a Randomized Controlled Study
Authors: Embon-Magal Shiri , Krasovsky Tal , Doron Israel , Asraf Kfir , Haimov Iris , Gil Efrat , Agmon Maayan 
Published: January 2022

Abstract
Background. Cognition and motor skills are interrelated throughout the aging process and often show simultaneous deterioration among older adults with cognitive decline. Co-dependent training has the potential to ameliorate both domains; however, its effect on the gait and cognition of older adults with cognitive decline has yet to be explored. The aim of this study is to compare the effects of the well-established single-modality cognitive computerized training program, CogniFit, with “Thinking in motion (TIM),” a co-dependent group intervention, among community-dwelling older adults with cognitive decline. Methods. Employing a single-blind randomized control trial design, 47 community-dwelling older adults with cognitive decline were randomly assigned to eight-week thrice weekly trainings of TIM or CogniFit. Pre- and post-intervention assessments included cognitive performance, evaluated by a CogniFit battery, as a primary outcome, and gait, under single- and dual-task conditions, as a secondary outcome. Results. CogniFit total Z scores significantly improved from baseline to post-intervention for both groups. There was a significant main effect for time [F (1, 44) = 17.43, p<.001, ηp2=.283] but not for group [F (1, 44) = 0.001, p=.970]. No time X group interaction [F (1, 44) = 1.29, p=.261] was found. No changes in gait performance under single and dual-task performance were observed in both groups. Conclusions. The findings show that single-modality (CogniFit) and co-dependent (TIM) trainings improve cognition but not gait in older adults with cognitive decline. Such investigations should be extended to include various populations and a broader set of outcome measurements. Trial registration: anzctr Id: 371522. Date: 08/11/2016
Tomodensitometric Bone Anatomy of The Intervertebral Foramen of The Lower Cervical Spine: Measurements and Comparison of Foraminal Volume in Healthy Individuals and Patients Suffering from Cervicobrachial Neuralgia Due to Foraminal Stenosis.
Authors: COUDERT Pierre , LAINE Gaetan , POINTILLART Vincent , DAMADE Camille , BOISSIERE Louis , VITAL Jean-Marc , BOUYER Benjamin , GILLE Olivier 
Published: January 2022

Abstract
Purpose

Degenerative foraminal stenosis of the cervical spine can lead to cervicobrachial neuralgias. Computed tomography (CT)-scan assists in the diagnosis and evaluation of foraminal stenosis. The main objective of this study is to determine the bony dimensions of the cervical intervertebral foramen and to identify which foraminal measurements are most affected by degenerative disorders of the cervical spine. These data could be applied to the surgical treatment of this pathology, helping surgeons to focus on specific areas during decompression procedures.
Methods

A descriptive study was conducted between two groups: an asymptomatic one (young people with no evidence of degenerative cervical spine disorders) and a symptomatic one (experiencing cervicobrachial neuralgia due to degenerative foraminal stenosis). Using CT scans, we determined a method allowing measurements of the following foraminal dimensions: foraminal height (FH), foraminal length (FL), foraminal width in its lateral part ((UWPP, MWPP and IWPP (respectively Upper, Medial and Inferior Width of Pedicle Part)) and medial part (UWMP, MWMP and IWMP (respectively Upper, Medial and Inferior Width of Medial Part)), and disk height (DH). Foraminal volume (FV) was calculated considering the above data. Mean volumes were measured in the asymptomatic group and compared to the values obtained in the symptomatic group.
Results

Both groups were made up of 10 patients, and a total of 50 intervertebral discs (100 intervertebral foramina) were analyzed in each group. Comparison of C4C5, C5C6 and C6C7 levels between both groups showed several significant decreases in foraminal dimensions (p< 0,05) as well as in foraminal volume (p <0.001) in the symptomatic group. The most affected dimensions were UWPP, MWPP, UWMP, MWMP and FV. The most stenotic foraminal areas were the top of the uncus and the posterior edge of the lower plate of the overlying vertebra.
Conclusion

Using a new protocol for measuring foraminal volume, the present study refines the current knowledge of the normal and pathological anatomy of the lower cervical spine and allows us to understand the foraminal sites most affected by degenerative stenosis. Those findings can be applied to foraminal stenosis surgeries. According to our results, decompression of the foramen in regard of both uncus osteophytic spurs and inferior plate of the overlying vertebra might be an important step for nerve roots release.
Interphase misorientation as a tool to study metamorphic reactions and crystallization in geological materials
Authors: Morales Luiz F.G. 
Published: January 2022

AbstractInterphase boundaries are planar defects that separate two different minerals, which in general have different compositions and/or crystalline structures; they may play an important role as a pathway for fluids in rocks and affect their physical properties. To completely characterize interphase boundaries, one needs to define the misorientation between adjacent grains and the orientation of the grain boundary plane. The analysis performed here is limited to the misorientation characterization and the trace of the interphase boundary. Although the determination of possible orientation relationships between the two adjacent phases is routinely performed by selected-area electron diffraction in a transmission electron microscope, this method lacks statistical representativeness. With the advent of techniques like electron backscatter diffraction (EBSD), it is possible to calculate orientation relationships not only in single pairs of crystals of the same phase but in full thin sections and between different minerals. The interphase misorientation is calculated from two orientations of two adjacent crystals of different phases. A set of single misorientations is then used to calculate the misorientation distribution function (MDF), from where it is possible to identify a maximum and its crystallographic interpretation. If we then know the misorientation and the unit-cell parameters of the individual phases, the crystal-lographic relationships between the different phases can be described with the pairs of parallel crystal-lographic planes and the pairs of crystallographic directions. In this paper, I present examples of the use of interphase misorientation analysis on the transformation of calcite-aragonite, olivine-antigorite, magnetite-hematite, and on the study of orientation relationships between plagioclase-olivine-ilmenite in mid-ocean ridges gabbros (ODP Hole 735).