bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prelabor rupture of membranes at term: A possible hematological triage in addition to vagino-rectal beta-hemolytic streptococcus screening for early labor induction
Authors: D’Ambrosi Francesco , Cesano Nicola , Iurlaro Enrico , Ronchi Alice , Ramezzana Ilaria Giuditta , Di Maso Matteo , Pietrasanta Carlo , Ronchi Andrea , Pugni Lorenza , Ferrazzi Enrico 
Published: January 2022

Introduction
A potential complication of term prelabor rupture of membranes (term PROM) is chorioamnionitis with an increased burden on neonatal outcomes of chronic lung disease and cerebral palsy. The purpose of the study was to analyze the efficacy of a standing clinical protocol designed to identify women with term PROM at low risk for chorioamnionitis, who may benefit from expectant management, and those at a higher risk for chorioamnionitis, who may benefit from early induction.

Material and methods
This retrospective study enrolled all consecutive singleton pregnant women with term PROM. Subjects included women with at least one of the following factors: white blood cell count ≥ 15×100/μL, C-reactive protein ≥ 1.5 mg/dL, or positive vaginal swab for beta-hemolytic streptococcus. These women comprised the high risk (HR) group and underwent immediate induction of labor by the administration of intravaginal dinoprostone. Women with none of the above factors and those with a low risk for chorioamnionitis waited for up to 24 hours for spontaneous onset of labor and comprised the low-risk (LR) group.

Results
Of the 884 consecutive patients recruited, 65 fulfilled the criteria for HR chorioamnionitis and underwent immediate induction, while 819 were admitted for expectant management. Chorioamnionitis and Cesarean section rates were not significantly different between the HR and LR groups. However, the prevalence of maternal fever (7.7% vs. 2.9%; p = 0.04) and meconium-stained amniotic fluid was significantly higher in the HR group than in LR group (6.1% vs. 2.2%; p = 0.04). This study found an overall incidence of 4.2% for chorioamnionitis, 10.9% for Cesarean section, 0.5% for umbilical artery blood pH < 7.10, and 1.9% for admission to the neonatal intensive care unit. Furthermore, no confirmed cases of neonatal sepsis were encountered.

Conclusions
A clinical protocol designed to manage, by immediate induction, only those women with term PROM who presented with High Risk factors for infection/inflammation achieved similar maternal and perinatal outcomes between such women and women without any risks who received expectant management. This reduced the need for universal induction of term PROM patients, thereby reducing the incidence of maternal and fetal complications without increasing the rate of Cesarean sections.
Lingering effects of COVID-19 on the mental health of first-year university students in Japan
Authors: Horita Ryo , Nishio Akihiro , Yamamoto Mayumi 
Published: January 2022

Background
The coronavirus disease 2019 (COVID-19) pandemic is continuing unabated in Japan, as of October 2021. We aimed to compare first-year university students’ psychological distress before the pandemic in 2019, during the pandemic in 2020, and one year after the onset of the pandemic, in 2021.

Methods
The study conducted online surveys over three years from April to May each year. Participants were 400 first-year students in 2019, 766 in 2020, and 738 in 2021. We examined differences in scores on the Counseling Center Assessment of Psychological Symptoms—Japanese version (CCAPS-Japanese) between the three years using a one-way analysis of variance, and differences in the CCAPS-Japanese critical items using chi-squared test and residual analysis.

Results
The average scores on the Depression and Generalized Anxiety subscale in 2021 were significantly higher than those in 2020, but remained the same as in 2019. The Academic Distress subscale score in 2020 was the worst compared to 2019 and 2021. Meanwhile, the number of students who experienced severe suicidal ideation increased year by year from 2019 to 2021.

Conclusion
The mean mental health of first-year university students worsened after the onset of the COVID-19 pandemic, and recovered to the pre-pandemic level over the next two years. However, the number of high-risk students with suicidal ideation continued to increase. A system is required for early detection and support for students at high risk of mental health issues.
Diabetes mellitus type 1 in children and adolescents in Moscow. Data from the Moscow Segment of the Federal Register of Diabetic Patients 2015–2020
Authors: Petryaykina E. E. , Laptev D. N. , Vorontsova I. G. , Demidov N. A. , Ryapolova Yu. А. 
Published: January 2022

BACKGROUND: Therapy for type 1 diabetes mellitus (T1DM) is still largely an unsolved clinical problem. Despite the introduction into clinical practice of modern insulin preparations, devices for its administration, as well as continuous monitoring of glucose levels, the goals of therapy are often not achieved. At the same time, the International Diabetes Federation (IDF) notes an increase in the prevalence and incidence of T1DM in children and adolescents in the world. The Federal Register of Diabetes Mellitus (FRDM) is a dynamically updated database of patients with diabetes, which allows assessing prevalence and incidence rates, achievement of glycemic control goals and the incidence of diabetes complications.AIM: analyze the epidemiological data of T1DM (prevalence, morbidity) in children and adolescents (patients from birth to 18 years of age) in Moscow according to the FRSD data and to assess their dynamics, as well as the dynamics of achieving the goals of glycemic control and the incidence of T1DM complications in 2015-2020.MATERIALS AND METHODS: The object of the study is a sample from the database of the Moscow segment of the FRDM of a cohort of patients with type 1 diabetes under 18 years of age who were registered for the period 01.01.2015-01.01.2021. Epidemiological prevalence and incidence rates are calculated per 100,000 of the relevant population.RESULTS: the number of children and adolescents with type 1 diabetes in Moscow as of 01.01.2021 was 4024 people (2962 children and 1062 adolescents). Over the period from 2015 to 2020, there was an increase in the prevalence of T1DM (possibly due to an increase in the quality of data registration in the FRSD) and a decrease in the incidence of both children and adolescents. There was also a decrease in the level of HbA1c and the proportion of patients with HbAc1> 8.0% among children with T1DM. Both children and adolescents with T1DM showed a decrease in the incidence of diabetic coma and ketoacidosis with a simultaneous increase in the incidence of severe hypoglycemia, as well as a decrease in the incidence of retinopathy and nephropathy. However, the incidence of neuropathy decreased among children and increased among adolescents.CONCLUSION: The data obtained on the dynamic management of adolescents with T1DM are the basis for considering the development of a profile program for their dynamic observation, taking into account the need for psychological and social support for patients and their families.
T-lymphocytes phenotypic composition of peripheral blood in patients with Graves’ disease undergoing conservative therapy with thiamazole
Authors: Dudina M. A. , Dogadin S. A. , Savchenko A. A. , Belenyuk V. D. 
Published: January 2022

BACKGROUND: Effective control of autoimmune inflammation in Graves’ disease determines necessity to study the T helper (Th) and cytotoxic T-lymphocytes dysfunction, as well as the level of regulatory T-cells (Treg) activation in patients with Graves’ disease on thyrostatic medication, which will clarify the immunomodulatory effects of long-term thiamazole treatment serve as targets for more specific therapies.AIM: To study the phenotypic composition of T-lymphocytes in the peripheral blood of patients with Graves’ disease to assess the direction of immune response depending on thimazole-induced euthyroidism duration.MATERIALS AND METHODS: A single-center, cohort, continuous, open-label, controlled trial was conducted to assess the phenotypic composition of T-lymphocytes in peripheral blood in women with Graves’ disease on long-term thiamazole treatment. The phenotypic composition of T-lymphocytes was determined by flow cytometry using direct immunofluorescence with conjugated FITC monoclonal antibodies depending on the duration of thimazole-induced euthyroidism of long-term thiamazole treatment.RESULTS: The study included 135 women with Graves’ disease, mean age 43.09±12.81 years, 120 (88.91%) with a relapse of the disease and 15 (11.09%) with newly diagnosed hyperthyroidism. An increase of activated CD3+CD4+CD25+ was found in patients with Graves’ disease with a duration of thimazole-induced euthyroidism 5–8 months and 9–12 months, respectively, Me=0.94 (0.48–1.45), p=0.020) and Me=0.95 (0.41–1.80), p=0.025), in control group — Me=0.12 (0.03–0.68). Compared to the control an increase of CD4+CD25+CD127Low (Treg) was found in patients with a duration of thimazole-induced euthyroidism 5–8 and 9–12 months. The content of Treg in peripheral blood in Graves’ disease patients with a duration of thimazole-induced euthyroidism more than 12 months decreases, but remains elevated relative to the control.CONCLUSION: In patients with Graves’ disease with a duration of thimazole-induced euthyroidism 5–8 months and 9–12 months the level of Treg has been increased. The increase of activated Th (CD3+CD4+CD25+) persists independently of thimazole-induced euthyroidism. In patients with Graves’ disease with a duration of thimazole-induced euthyroidism for more than 12 months, there is a compensatory increase in regulatory T-lymphocyte, and the total number of T-helpers is restored to the control.
Differences in plasma miRNA levels in inferior petrosal sinus samples of patients with ACTH-dependent Cushing’s syndrome
Authors: Malygina A. A. , Belaya Z. E. , Nikitin A. G. , Koshkin P. A. , Sitkin I. I. , Lapshina A. M. , Khandaeva P. M. , Lutsenko A. S. , Trukhina D. A. , Melnichenko G. A. 
Published: January 2022

BACKGROUND: For the last decades microRNAs (miR) have proven themselves as novel biomarkers for various types of diseases. Identification of specific circulating microRNA panel that differ patient with Cushing’s disease (CD) and ectopic ACTH syndrome (EAS) could improve the diagnostic procedure.AIM: to evaluate the differences in miR levels in plasma samples drained from inferior petrosal sinuses in patients with CD and EAS.MATERIALS AND METHODS: single-center, case-control study: we enrolled 24 patients with ACTH-dependent Cushing’s syndrome (CS) requiring bilateral inferior petrosal sinus sampling (BIPSS). Among them 12 subjects were confirmed as CD (males=2, females=10; median age 46,5 [IR 33,8;53,5]) and 12 as EAS (males=4, females=8, median age 54 [IR 38,75;60,75]). BIPSS was performed through a percutaneous bilateral approach. Once catheters were properly placed, blood samples were withdrawn simultaneously from each petrosal sinus and a peripheral vein. Plasma samples from both sinuses were centrifuged and then stored at -80 C. MiRNA isolation from plasma was carried out by an miRneasy Plasma/Serum Kit (Qiagen, Germany) on the automatic QIAcube station according to the manufacturer protocol. To prevent degradation, we added 1 unit of RiboLock Rnase Inhibitor (Thermo Fisher Scientific, USA) per 1 μL of RNA solution. The concentration of total RNA in the aqueous solution was evaluated on a NanoVue Plus spectrophotometer (GE Healthcare, USA). The libraries were prepared by the QIAseq miRNA Library Kit following the manufacturer standard protocols. MiR expression was then analyzed by sequencing on Illumina NextSeq 500 (Illumina, USA).RESULTS: 108 miRNAs were differently expressed (p <0,05) in inferior petrosal sinus samples of patients with CD vs EAS. We divided these miRNAs into 3 groups based on the significance of the results. The first group consisted of samples with the highest levels of detected miR in both groups. Four miRNAs were included: miR-1203 was downregulated in CD vs EAS — 36.74 (p=0,013), and three other were upregulated in CD vs EAS: miR-383-3p 46.36 (p=0,01), miR-4290 6.84 (p=0,036), miR-6717-5p 4.49 (p=0,031). This miRs will be validated in larger cohorts using RT-qPCR.CONCLUSION: Plasma miR levels differ in inferior petrosal samples taken from patients with CD vs EAS. These miRs need to be validated by different methods and in peripheral plasma samples in order to be used as potentially non-invasive biomarkers to differentiate ACTH-dependent CS.
DINAMIKA KONFLIK IDENTITAS PENGHAYAT SAPTA DARMA DI DESA SUKORENO, JEMBER, JAWA TIMUR
Authors: Hasanah Fitriatul , Widianto Ahmad Arif , Gita Purwasih Joan Hesti 
Published: January 2022

The polemic of religious identity between “penghayat kepercayaan” (believers of indigenous religion) and followers of the official religions in Indonesia is still become a sensitive issue, which adds to the long list of marginalization of indigenous believers in Indonesia. Several forms of marginalization are: forcing to choose certain official religions in their National ID Card, the pros and cons of the burial places of the deceased indigenous believers, and restrictions on the construction of their worship places. This article aims to elaborate the dynamics of identity conflict between adherents of the Sapta Darma (one of indigenous belief) and the followers of official religions in Sukoreno Village, Jember, East Java. This study uses a qualitative approach using observation, in-depth interviews with 7 (seven) informants of Sapta Darma followers, and members of FKUB (Forum of Religious Harmony) for the data collection. The results of the study reveal that this identity polemic has made it difficult for adherents of Sapta Dharma to change their religious identity on their ID cards. As a consequence, they also have difficulty in accessing public burial places. Conflict resolution efforts are carried out through FKUB by providing socialization of knowledge on nationality and cultural perspective to the interfaith leaders. Polemik identitas agama antara penghayat kepercayaan dengan pemeluk agama resmi di Indonesia masih menjadi isu yang menambah daftar panjang marginalisasi penganut kepercayaan di Indonesia. Bentuk marginalisasi ini mengarah kepada pemaksaan pencantuman agama tertentu dalam KTP dan KK warga penghayat, pro dan kontra tempat pemakaman warga penghayat yang meninggal, dan pembatasan pembangunan rumah peribadatan bagi warga penghayat. Artikel ini bermaksud untuk mengelaborasi dinamika konflik identitas antara penghayat kepercayaan Sapta Darma dengan para pemeluk agama resmi, dengan mengambil lokasi tempat di Desa Sukoreno, Jember, Jawa Timur. Penelitian ini menggunakan pendekatan kualitatif dengan teknik pengumpulan data berupa observasi, wawancara mendalam terhadap 7 (tujuh) informan warga penghayat Sapta Darma, dan anggota FKUB (Forum Kerukunan Umat Beragama). Hasil penelitian mengungkapkan bahwa polemik identitas ini mengakibatkan warga pengahayat kesulitan dalam mengganti identitas agamanya di KTP dan KK sehingga mereka memiliki identitas ganda dan kesulitan dalam mengakses tempat pemakaman umum. Upaya resolusi konflik dilakukan melalui FKUB dengan memberikan sosialisasi wawasan kebangsaan dan pendekatan kultural dengan tokoh lintas agama.
CENTRALISTIC REFORM: A CRITICAL DISCOURSE ANALYSIS OF TAX REFORM CAMPAIGN IN THE DIRECTORATE GENERAL OF TAXES
Authors: Andayani Tri Juniati , Puspa Ratih , Subiakto Henri 
Published: January 2022

The Directorate General of Taxes (DGT) has been running a tax reform program to enable a comprehensive transformation in the taxation system to create a strong, credible, and accountable tax institution. This program enhances equitable taxation and an excellent and integrated data expansion to increase tax revenues. The discourses on tax reform are primarily promoted on DGT communication channels, including its online social media. This discourse leads to a likely impact of a partial taxation system. Thisresearch aims to analyze the discourse of tax reform on the online social media of DGT using Norman Fairclough’s Critical Discourse Analysis based on texts on online media as the primary data. It was revealed that DGT conveys messages about tax reform in three ways: tax reformation as a public communication campaign, discourse of Indonesia taxation transparency, and discourse of taxation in the Directorate General of Taxes to face the 4.0 industrial revolution. DGT conveys these three discourses according to its work scope as a state institution that constantly strives for making transformations through its programs that are carried out based on the provisions of the umbrella institutions, including the vision and mission of the President. In this case, the President’s vision and mission are inseparable from the demands of the times, international pressure, the history of the nation, and social changes in society.
Investigasi Pengambilan Keputusan Gen Y (Second Generation Existing Priority Members) untuk Menjadi Nasabah Prioritas BCA di Pekalongan (Sebuah Studi Fenomenologi)
Authors: Christianto Andreas Andy , Soesanto Harry 
Published: January 2022

Gen Y, which is often referred to as Generation Millennials, will soon dominate the composition of the world of work and business in Indonesia. This millennial generation has a significant difference with previous generations, especially about what influences are the basis of their purchasing decisions. The researcher specifically examined how this millennial generation decided to join as a BCA Priority customer, what factors influenced their decision. The researcher used the Qualitative research method with a phenomenological narrative approach. The reason for choosing this method is so that researchers can interact directly with the speakers, dig deeper so that they get a more comprehensive picture of them. There were 8 speakers in this study which were divided into 4 groups, namely 1. Parents and Children of Priority customers, 2. Parents of Priority customers, Children not Priority customers, 3. Parents not BCA customers, Priority customer Children,4. Parents and Children are not Priority customers, but are included in the Priority criteria. The results of this study indicate that millennial generation purchasing decisions are influenced by many factors that can be grouped into 2 things: factors that have been experienced, felt and fulfilled their needs, namely ease of transactions, privileges, special prices, business networks, and pride and other factors that are expectations what they want when they become priority customers, namely financial solutions and increasing their knowledge. The new finding in this study was that parents' factors turned out to play a very important role for Gen Y especially the second generation of priority customers to decide to become BCA Prioritas customers.
Enhancement of safety communication model
Authors: Schiller Frank , Judd Dan , Supavatanakul Peerasan , Hardt Tina , Wieczorek Felix 
Published: January 2022

Abstract
A fundamental measure of safety communication is the residual error probability, i. e., the probability of undetected errors. For the detection of data errors, typically a Cyclic Redundancy Check (CRC) is applied, and the resulting residual error probability is determined based on the Binary Symmetric Channel (BSC) model. The use of this model had been questioned since several error types cannot be sufficiently described. Especially the increasing introduction of security algorithms into underlying communication layers requires a more adequate channel model. This paper introduces an enhanced model that extends the list of considered data error types by combining the BSC model with a Uniformly Distributed Segments (UDS) model. Although models beyond BSC are applied, the hitherto method of the calculation of the residual error probability can be maintained.
Stemmatologisches
Authors: Ziffer Giorgio 
Published: January 2022

Abstract
This is the publication of a brief unknown text of one page, written by Paul Maas in October 1935, in which the very first definition and analysis of ‘separative’ and ‘conjunctive errors’ are given. What we have before us is in fact the germ of the seminal essay Leitfehler und stemmatische Typen which Maas published two years later in the “Byzantinische Zeitschrift”.
Digital Gender Divide and Convergence in the European Union Countries
Authors: López-Martínez María , García-Luque Olga , Rodríguez-Pasquín Myriam 
Published: January 2022

AbstractThe aim of this study is to examine the digital gender divide in the European Union (EU) countries by applying two widely used indicators: percentage of the population who has used the Internet in the last 3 months (ICT-USE indicator) and percentage of the population who has made an online purchase in the last 3 months (ICT-PURCHASE indicator). With these indicators, the digital gender gaps are shown in absolute and relative terms. In addition, the European convergence beta and sigma, between the years 2007 and 2019, is also analyzed. The results among European countries show that the ICT-USE indicator has a lower dispersion than the ICT-PURCHASE indicator; hence, in general, the digital gender divide or gap is usually lower when ICT-USE is used in comparison with ICT-PURCHASE. The highest values of the digital gender gap in the EU, regardless of the indicator used, are found in Croatia and Italy, reflecting an unfavorable position for women. Ireland is also in this group, but in its case, the results show an unfavorable position for men. Additionally, Cyprus does not register gender differences in either of the two indicators analyzed. Finally, the convergence between European countries is corroborated, both in the indicators analyzed and in the different gender digital gaps built.
Numerical study of the energy efficiency of the building envelope containing multi-alveolar structures under Tunisian weather conditions
Authors: Lajimi Nour , Ben Taher Nour , Boukadida Noureddine 
Published: January 2022

Abstract
The study of the thermal inertia of buildings is a subject of major interest. The thermal insulation and the nature of the wall sensitively modify the inertia of the building and are the solutions to improve the energy efficiency of the envelope. The roof is well exposed to solar radiation in summer and contributes to significant losses in winter due to convective exchanges. To lead to a thermal comfort, a thermal insulation is necessary. In this context, we carry out a numerical study of the thermal behavior of a building with two zones in variable meteorological conditions for a Tunisian climate (region of Sousse) based on the thermoelectric analogy and using the nodal method as a numerical method. The object of this work is to study the effect of the thermal inertia of the roof equipped with a multi-alveolar structure on the thermal behavior of the air inside the room and on its energy consumption. Taking into account the energy input of occupant, a complete model was established to increase the accuracy of the calculations. The results show that the multi-alveolar structure placed on the outside of the roof reduces energy consumption during the winter period when the alveolar structure is placed in the conductive direction and during the summer period when the alveolar structure is placed in the insulate direction.
Truth in Pastoral Practice: A Firmer Foundation for Contested Territory
Authors: Lasair Simon 
Published: January 2022

Abstract
Truth in the West is highly contested. The advent of post-truth politics, in addition to the ongoing culture wars, mitigates against truth being understood solely on the basis of objective facts, as it was in the past. For pastoral carers and counsellors, this raises significant questions: how to build shared understandings of truth between individuals and in communities? This article proposes a solution in an incarnational approach to pastoral work. Drawing upon the work of Rowan Williams, Raimon Panikkar, Diarmuid O’Murchu, and St. Maximos the Confessor, this article offers both theological and practical considerations regarding this approach.