bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Characteristics of Soil Organic Carbon (SOC) at Forest Stands of Mount-Merbabu National Park and Upland Farming
Authors: Suyana Jaka , Krismonanto Wisnu , Muliawati Endang Setia , Widijanto Hery , Hartati Sri 
Published: December 2022

AbstractThis study examines the characteristics of vegetation and SOC at forest stands of Mount-Merbabu National Park (Pine (Pinus merkusii), Puspa (Schima noronhae Theaceae), Acacia (Acacia decurren Fabaceae), Bintamin (Cupressussp), and Mixed) and upland farming at a soil depth of 0-70 cm. Observations of characteristics of vegetation stands were made by observing plot units measuring 50 m x 50 m and three replicates, while the observations of SOC included: organic-C and bulk density soil at a depth of 0-70 cm and three replicate. The research data were analyzed descriptively, followed by the F-Test and DMRT Test at 5% level. The results showed that the SOC content decreased with increasing soil depth (0-10, 10-20, 20-30, 30-50, 50-70 cm). At soil depth (0-70 cm), the highest SOC concentration and SOC stocks were in the Puspa (53.40 g C kg−1or 437.18 ton C ha−1), followed by Mixed (50.01 g C kg−1or 303.62 ton C ha−1), Bintamin (28.08 C kg−1or 198.70 ton C ha−1), Acacia (24.39 g C kg−1or 233.94 ton C ha−1), and the lowest is Pine (20.13 g C kg−1or 150.83 ton C ha−1); while the upland farming (15.28 g C kg−1or 103.38 ton C ha−1). Puspa can be recommended as a good type of revegetate plant.
Experimental observations of naturally occurring dust using a high-speed vacuum ultraviolet imaging system in EAST
Authors: HOU Shanwei , MING Tingfeng , SHI Qiqi , ZHANG Wenmin , LONG Feifei , LI Bang , DENG Rongjing , ZHUANG Qing , LIU Xiaoju , ZHANG Ling , TI Ang , ZENG Long , LI Guoqiang , ASHIKAWA Naoko , OHDACHI Satoshi , GAO Xiang 
Published: December 2022

Abstract
In the ELMy H-mode experiment, naturally occurring dust originating at the high-field side is clearly observed using the high-speed vacuum ultraviolet imaging system developed on the Experimental Advanced Superconducting Tokamak (EAST). The main ablation cloud shape is similar to the classical shape observed in pellet fueling experiments. However, during the dust penetration, an erupted secondary cloudlet with a bent ‘cigar’ shape is observed and moves upwards along the direction perpendicular to the magnetic field line, which is different to the obviation in the pellet fueling experiments. This may be due to the ion diamagnetic drift effect. The velocities of the secondary cloudlet are estimated to be 50‒80 m s−1. In addition, a significant degradation of the plasma confinement is observed during the dust penetration.
On the Deeply Moving and the Merely Touching
Authors: Cullhed Eric 
Published: December 2022

Abstract
Critics often link yet distinguish between ‘moving’ and ‘touching’ characters, scenes and artworks. It has been argued that being moved is a specific emotion, that its formal object is the thin goodness of exemplified final, important and impersonal thick values, and that being touched is an attenuated form of that phenomenon. First, I dispute that the values that move us must be impersonal, since we can be moved by the personal goodness of being loved, free or healthy. Second, I argue that being touched should be considered a distinct emotion type. To support this claim, I refer to apparent differences between the formal objects that the two affective phenomena relate to as well as to dissimilarities in cognitive sophistication and phenomenology. I suggest that we are touched by that which invites love. Vulnerable, innocently suffering and affectionate beings are touching insofar as they need and will be responsive to love.
Mitochondrial E3 ubiquitin ligase MARCH5 is required for mouse oocyte meiotic maturation
Authors: Zhou Qian , Xu Ke , Zhao Bing-Wang , Qiao Jing-Yi , Li Yuan-Yuan , Lei Wen-Long , Li Jian , Ouyang Ying-Chun , Hou Yi , Schatten Heide , Wang Zhen-Bo , Sun Qing-Yuan 
Published: December 2022

AbstractAs the most abundant organelles in oocytes, mitochondria play an important role in maintaining oocyte quality. Here, we report that March5, encoding a mitochondrial ubiquitin ligase that promotes mitochondrial elongation, plays a critical role in mouse oocyte meiotic maturation via regulating mitochondrial function. The subcellular localization of MARCH5 was similar to the mitochondrial distribution during mouse oocyte meiotic progression. Knockdown of March5 caused decreased ratios of the first polar body extrusion. March5-siRNA injection resulted in oocyte mitochondrial dysfunctions, manifested by increased reactive oxygen species, decreased ATP content as well as decreased mitochondrial membrane potential, leading to reduced ability of spindle formation and an increased ratio of kinetochore–microtubule detachment. Further study showed that the continuous activation of the spindle assembly checkpoint and the failure of Cyclin B1 degradation caused MI arrest and first polar body (PB1) extrusion failure in March5 knockdown oocytes. Taken together, our results demonstrated that March5 plays an essential role in mouse oocyte meiotic maturation, possibly via regulation of mitochondrial function and/or ubiquitination of microtubule dynamics- or cell cycle-regulating proteins.
Dissecting intratumor heterogeneity in HCC: new research strategies and clinical implications
Authors: Behrens Shay , Wang Xin Wei 
Published: December 2022

Abstract
Hepatocellular carcinoma (HCC) accounts for the majority of liver cancers and is driven by a multitude of viral, metabolic, and lifestyle factors initiating liver injury that subsequently progresses to cancer. Despite significant medical advancements, current treatment options are limited in their efficacy and overall survival remains poor. Recent studies have suggested that intratumor heterogeneity may play a significant role in treatment response, resistance, and overall prognosis. In this review, we will outline new techniques that utilize both human samples and non-human models to evaluate intratumor heterogeneity. Additionally, we will provide an overview of the clinical implications of intratumor heterogeneity on patients with HCC.
Multi-Product Pricing: Theory and Evidence from Large Retailers
Authors: Bonomo Marco , Carvalho Carlos , Kryvtsov Oleksiy , Ribon Sigal , Rigato Rodolfo 
Published: December 2022

Abstract
We study a unique dataset with comprehensive coverage of daily prices in large multi-product retailers in Israel. Retail stores synchronise price changes around occasional ‘peak’ days when they reprice around 10% of their products. To assess aggregate implications of partial price synchronisation, we develop a new model in which multi-product firms face economies of scope in price adjustment, and synchronisation is endogenous. Synchronisation of price changes attenuates the average price response to monetary shocks, but only high degrees of synchronisation can substantially strengthen the real effects of monetary policy shocks. Our calibrated model generates real effects similar in magnitude to those in M. Golosov, and R.E. Lucas, Journal of Political Economy (2007), vol. 115, pp. 171–99.
Table Mountain Pine (Pinus pungens): Genetic Diversity and Conservation of an Imperiled Conifer
Authors: Potter Kevin M , Jetton Robert M , Whittier W Andrew , Crane Barbara S , Hipkins Valerie D , Echt Craig S , Hodge Gary R 
Published: December 2022

AbstractTable Mountain pine (Pinus pungens Lamb.) is an imperiled tree species endemic to the southern and central Appalachian Mountains. Generally reliant on fire for regeneration, its fragmented but widespread distribution has declined in recent decades. We quantified the genetic diversity of 26 populations across the range of the species using data from seven highly polymorphic simple sequence repeat (SSR) loci. The species was relatively inbred whereas differentiation among populations was relatively low. Differentiation was significantly but weakly associated with geographic distance among populations. We detected minor genetic differences between northern and southern seed collection zones established based on climate similarity. We conducted a series of simulations using SSR data from 498 seedlings, grown from seed collected from five natural stands of Table Mountain pine, to assess the genetic consequences of different strategies for deploying collected seed in ex situ conservation plantings. Results indicated that reducing the number of families in a planting would not substantially affect the conservation of common alleles but would affect the representation of rare alleles and overall allelic richness. These findings add to our limited knowledge of genetic variation across the distribution of this rare conifer and offer some guidance for its effective genetic conservation.
Predictive model-based interventions to reduce outpatient no-shows: a rapid systematic review
Authors: Oikonomidi Theodora , Norman Gill , McGarrigle Laura , Stokes Jonathan , van der Veer Sabine N , Dowding Dawn 
Published: December 2022

AbstractObjectiveOutpatient no-shows have important implications for costs and the quality of care. Predictive models of no-shows could be used to target intervention delivery to reduce no-shows. We reviewed the effectiveness of predictive model-based interventions on outpatient no-shows, intervention costs, acceptability, and equity.Materials and MethodsRapid systematic review of randomized controlled trials (RCTs) and non-RCTs. We searched Medline, Cochrane CENTRAL, Embase, IEEE Xplore, and Clinical Trial Registries on March 30, 2022 (updated on July 8, 2022). Two reviewers extracted outcome data and assessed the risk of bias using ROB 2, ROBINS-I, and confidence in the evidence using GRADE. We calculated risk ratios (RRs) for the relationship between the intervention and no-show rates (primary outcome), compared with usual appointment scheduling. Meta-analysis was not possible due to heterogeneity.ResultsWe included 7 RCTs and 1 non-RCT, in dermatology (n = 2), outpatient primary care (n = 2), endoscopy, oncology, mental health, pneumology, and an magnetic resonance imaging clinic. There was high certainty evidence that predictive model-based text message reminders reduced no-shows (1 RCT, median RR 0.91, interquartile range [IQR] 0.90, 0.92). There was moderate certainty evidence that predictive model-based phone call reminders (3 RCTs, median RR 0.61, IQR 0.49, 0.68) and patient navigators reduced no-shows (1 RCT, RR 0.55, 95% confidence interval 0.46, 0.67). The effect of predictive model-based overbooking was uncertain. Limited information was reported on cost-effectiveness, acceptability, and equity.Discussion and ConclusionsPredictive modeling plus text message reminders, phone call reminders, and patient navigator calls are probably effective at reducing no-shows. Further research is needed on the comparative effectiveness of predictive model-based interventions addressed to patients at high risk of no-shows versus nontargeted interventions addressed to all patients.
A multi-plex protein expression system for production of complex enzyme formulations in Trichoderma reesei
Authors: Subramanian Venkataramanan , Farmer Samuel J , Heiland Kelsey L , Moore Kyle T , Wall Todd A Vander , Sun Weiman , Chaudhari Yogesh B , Himmel Michael E , Decker Stephen R 
Published: December 2022

Abstract
Heterologous protein production has been challenging in the hyper-cellulolytic fungus, Trichoderma reesei as the species is known for poor transformation efficiency, low homologous recombination frequency, and marginal screening systems for the identification of successful transformants. We have applied the 2A-peptide multi-gene expression system to co-express four proteins, which include three cellulases: a cellobiohydrolase (CBH1), an endoglucanase (EG1), and a β-D-glucosidase (BGL1), as well as the enhanced green fluorescent protein (eGFP) marker protein. We designed a new chassis vector, pTrEno-4X-2A, for this work. Expression of these cellulase enzymes was confirmed by real-time quantitative reverse transcription PCR and immunoblot analysis. The activity of each cellulase was assessed using chromogenic substrates, which confirmed the functionality of the enzymes. Expression and activity of these enzymes were proportional to the level of eGFP fluorescence, thereby validating the reliability of this screening technique. An 18-fold differencein protein expression was observed between the first and third genes within the 2A-peptide construct. The availability of this new multi-gene expression and screening tool is expected to greatly impact multi-enzyme applications, such as the production of complex commercial enzyme formulations and metabolic pathway enzymes, especially those destined for cell-free applications.
Effect of Pepper Variety on the Susceptibility of Pepper Weevil Parasitoids
Authors: Murillo-Hernández Juan Eduardo , Lomeli-Flores J Refugio , Rodríguez-Leyva Esteban , Soto-Rojas Lauro , Torres-Ruiz Alfonso , Santillán-Galicia Ma Teresa , Muñíz-Reyes Érica 
Published: December 2022

Abstract
Anthonomus eugenii Cano (Coleoptera: Curculionidae) is a key pest of cultivated peppers (Capsicum species) in tropical and subtropical America. Here we evaluated the effect of five pepper varieties on the susceptibility of A. eugenii to the parasitoids Bracon sp. (Hymenoptera: Braconidae), Eupelmus cushmani (Crawford) (Hymenoptera: Eupelmidae), and Jaliscoa hunteri Crawford (Hymenoptera: Pteromalidae). Potential parasitism was estimated by comparative analysis of parasitoid ovipositor size and the depth to which host larvae develop inside the fruit. Highest potential parasitism rates were achieved by Bracon sp. and E. cushmani on árbol and habanero peppers (84–99%) while the lowest rates were achieved by J. hunteri on serrano, bell, and jalapeño (7–18%). To validate potential parasitism rates, the actual parasitism rate by Bracon sp. and J. hunteri on three varieties of peppers was assessed. Actual parasitism rates of A. eugenii larvae in árbol were similar for Bracon sp. and J. hunteri (33%), while on bell and jalapeño Bracon sp. achieved 24% and 13% parasitism and J. hunteri achieved 14% and 8%, respectively. In most cases, actual parasitism was lower than estimated potential parasitism, although the latter had a notable predictive power (predicted R2 = 0.84). Results showed that the host was more vulnerable on small-fruited varieties because larvae were closer to the pericarp and could be reached by parasitoid ovipositors; likewise, in varieties with little placenta and seed, some larvae fed in the pericarp, where they were more vulnerable.
Inflammatory and insulinemic dietary patterns and risk of endometrial cancer among US women
Authors: Romanos-Nanclares Andrea , Tabung Fred K , Sinnott Jennifer A , Trabert Britton , De Vivo Immaculata , Playdon Mary C , Eliassen A Heather 
Published: December 2022

Abstract

Background
Although unopposed estrogen exposure is considered a major driver of endometrial carcinogenesis, chronic inflammation and insulin resistance and hyperinsulinemia are also major endometrial cancer risk factors. However, it is unclear whether diets with inflammatory or insulinemic potential are associated with risk of endometrial cancer.

Methods
We followed 48 330 women from the Nurses’ Health Study (1984-2016) and 85 426 women from the Nurses’ Health Study II (1989-2017). Using food frequency questionnaires, we calculated repeated measures of empirical dietary inflammatory pattern (EDIP) and empirical dietary index for hyperinsulinemia (EDIH) scores, which characterize the potential of the whole diet to modulate circulating biomarkers of inflammation or C-peptide, respectively. We used multivariable-adjusted Cox regression to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for type I endometrial cancer risk.

Results
We documented 1462 type I endometrial cancer cases over 2 823 221 person-years of follow-up. In the pooled multivariable-adjusted analyses, women in the highest compared with lowest quintiles were at higher risk of type I endometrial cancer (EDIP HRQ5vsQ1 = 1.46, 95% CI = 1.24 to 1.73; Ptrend &lt; .001; EDIH HRQ5vsQ1 = 1.58, 95% CI = 1.34 to 1.87; Ptrend &lt; .001). Additional adjustment for body mass index attenuated the associations (EDIP HR = 1.03, 95% CI = 0.87 to 1.22; EDIH HR = 1.01, 95% CI = 0.85 to 1.21), and mediation analyses showed that body mass index may explain 60.4% (95% CI = 37.4% to 79.6%; P &lt; .001) and 71.8% (95% CI = 41.0% to 90.4%; P &lt; .001) of the association of endometrial cancer with EDIP and EDIH, respectively.

Conclusions
In this large cohort study, higher dietary inflammatory and insulinemic potential were each associated with increased endometrial cancer incidence, and this association may be almost entirely mediated by adiposity.
Linguistic Features of Public Service Encounters: How Spoken Administrative Language Affects Citizen Satisfaction
Authors: Eckhard Steffen , Friedrich Laurin 
Published: December 2022

Abstract
Spoken administrative language is a critical element in the relationship between citizens and the state, especially when it comes to face-to-face interactions between officials and citizens during the delivery of public services. But preceding work offers little insights into the verbal features of street-level bureaucracy. Drawing on communication studies, we argue that administrative language differs along both a relational and an informational linguistic component. To test the consequentiality of this theory, we design a factorial survey experiment with a representative sample of 1,402 German citizens. Participants evaluated audio recordings of a hypothetical service encounter where we systematically varied the language used by the official and the service decision, measuring participants’ service satisfaction as the main outcome. Based on regression analysis, we find that relational elements of administrative language improve citizen satisfaction, independent of the service outcome, but that the effect does not hold for the informational component. These findings emphasize the importance of relational communication in citizen-state interactions, which tends to be neglected in public administration theory and practice.
Interactive effects of plant density and nitrogen availability on the biomass production and leaf stoichiometry ofArabidopsis thaliana
Authors: Yan Zheng-Bing , Tian Di , Huang Han-Yue , Sun Yuan-Feng , Hou Xing-Hui , Han Wen-Xuan , Guo Ya-Long , Fang Jing-Yun 
Published: December 2022

AbstractPlant density and nitrogen (N) availability influence plant survival and nutrient use strategies, but the interaction between these two factors for plant growth and the balance of elements remains poorly addressed. Here, we conducted experimental manipulations using Arabidopsis thaliana, with the combination of four levels of plant density and four levels of N addition, and then examined the corresponding changes in plant biomass production (indicated by total plant biomass and biomass partitioning) and nutrient use strategies (indicated by leaf N and phosphorus (P) stoichiometry). The biomass–density relationship was regulated by N availability, with a negative pattern in low N availability but an asymptotic constant final yield pattern at high N availability. Excessive N addition reduced plant growth at low plant density, but this effect was alleviated by increasing plant density. The root to shoot biomass ratio increased with plant density at low N availability, but decreased at high N availability. N availability was more important than plant density in regulating leaf N and P stoichiometry, with the increasing leaf N concentration and decreasing leaf P concentration under increasing N addition, resulting in a negative scaling relationship between these two elemental concentrations. Our results show that N availability and plant density interactively regulate plant biomass production and leaf stoichiometry of A. thaliana, and highlight that the interactive effects of these two factors should be considered when predicting plant growth behaviour under intraspecific competitive environments in the context of nutrient changes.
Plant phosphate status influences root biotic interactions
Authors: Pazhamala Lekha T , Giri Jitender 
Published: December 2022

AbstractPhosphorus (P) deficiency stress in combination with biotic stress(es) severely impacts crop yield. Plant responses to P deficiency overlapping with that of other stresses exhibit a high degree of complexity involving different signaling pathways. On the one hand, plants engage with rhizosphere microbiome/arbuscular mycorrhizal fungi for improved phosphate (Pi) acquisition and plant stress response upon Pi deficiency; on the other hand, this association is gets disturbed under Pi sufficiency. This nutrient-dependent response is highly regulated by the phosphate starvation response (PSR) mediated by the master regulator, PHR1, and its homolog, PHL. It is interesting to note that Pi status (deficiency/sufficiency) has a varying response (positive/negative) to different biotic encounters (beneficial microbes/opportunistic pathogens/insect herbivory) through a coupled PSR–PHR1 immune system. This also involves crosstalk among multiple players including transcription factors, defense hormones, miRNAs, and Pi transporters, among others influencing the plant-biotic–phosphate interactions. We provide a comprehensive view of these key players involved in maintaining a delicate balance between Pi homeostasis and plant immunity. Finally, we propose strategies to utilize this information to improve crop resilience to Pi deficiency in combination with biotic stresses.
Early-type dwarf galaxies in the local universe. Evidence of ex situ growth
Authors: Paudel Sanjaya , Yoon Suk-Jin , Moon Jun-Sung , Chhatkuli Daya Nidhi 
Published: December 2022

ABSTRACT
We report the discovery of a rare early-type dwarf galaxy (dE), SDSS J125651.47+163024.2 (hereafter, dE1256), possessing a tidal feature that was likely built up by accretion of an even smaller dwarf galaxy. dE1256 is located in a nearly isolated environment, at the outskirt of the Virgo cluster. A detailed morphological examination reveals that the accreted stellar population is mainly deposited in the outer part of dE1256, where the tidal tail is most prominent. The inner part of dE1256 is perfectly modelled with a simple Sérsic function of index n = 0.63 and half-light radius Rh = 0.6 kpc, but in contrast, the entire galaxy has a size of Rh = 1.2 kpc. The mass ratio between the host and the putative accreted dwarf galaxy is calculated to be 5:1, assuming that the observed two components, inner Sérsic and outer tidal tail residual, represent the host’s and accreted galaxy’s stellar populations, respectively. We suggest that while the accretion contributes only 20 per cent of the overall stellar population, the size of dE1256 grew by a factor of two via the accretion event. Our results provide, for the first time, strong observational evidence that a dE is undergoing a two-phase growth, a common phenomenon for massive galaxies.