bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seismic Signature of Rain and Wind Inferred From Seismic Data
Authors: Rindraharisaona E. J. , Réchou A. , Fontaine F. R. , Barruol G. , Stamenoff P. , Boudevillain B. , Rigaud‐Louise F. , Delcher E. 
Published: October 2022

AbstractSeismic stations are increasingly used to monitor river activity and to quantify sediment transport during flood events. In tropical regions, cyclone‐induced floods are often associated with heavy rain and strong wind episodes, generating complex seismic records involving the simultaneous signature of water, sediment, rainfall and wind. Hence, seismic characterization of rain and wind is then required to better decipher each process and improve our understanding of the river seismic signature. In this study, we investigate experimentally the seismic response of rain and wind using data recorded by geophones deployed in various soil types and at different burial depth (BD), co‐located with various meteorological instruments. Our results show that the power spectral density (PSD) of the seismic noise intensifies at a frequency between 60 and 500 Hz for rain and 5 and 500 Hz for wind, in the presence of rain precipitation as low as 0.025 mm/min and/or wind speed ≥3 m/s. PSD analysis indicates that the seismic signal associated with rain decreases with the BD with a value of ∼2–5 dB in a depth difference of 10 cm. We also observe that each soil type has its own seismic signature. The 4‐min root mean square correlation between the seismic signal amplitude and the rain precipitation suggests that they best correlate with Pearson coefficient >0.90 at BD of 30 cm. The transfer function between the precipitation rate (or kinetic energy) and the seismic signal amplitude shows that the signal recorded by the geophone can be used as a robust proxy for these parameters.
Basin Sediments Geometry and Strength as Controls for Post‐Failure Emplacement Style of Alpine Sub‐Lacustrine Landslides
Authors: Klein B. , Puzrin A. M. , Stoecklin A. , Kopf A. 
Published: October 2022

AbstractPredicting the evolution of underwater mass movements in their post‐failure stage is vital for risk assessment of offshore structures and ensuring safety of coastal communities threatened by tsunami waves. In the absence of sedimentological and geotechnical data, variability of the post‐failure behavior in a specific marine or lacustrine setting is often attributed to predisposition factors such as the slope height‐drop and depth to the basal shear surface. In this paper, the contribution of other geometrical parameters such as the slope inclination and the relative thickness of the frontal basin sediments is investigated using a coupled Eulerian‐Lagrangian finite element framework. An emphasis is given to the important role of the strength difference between the slope and frontal basin sediments. The suggested framework is first validated against the well‐documented Zinnen slide in Lake Lucerne (Switzerland), successfully reproducing the post‐failure geometry and capturing the main features observed in published seismic profiles. It is then applied in a parametric study to illustrate the decisive role of the frontal basin sediments in determining the post‐failure geometry of underwater mass wasting in similar settings.
Electromagnetic Ducting in the Near‐Shore Marine Environment: Results From the CASPER‐East Field Experiment
Authors: Alappattu Denny P. , Wang Qing , Yamaguchi Ryan T. , Haack Tracy , Ulate Marcela , Fernando Harindra J. , Frederickson Paul 
Published: October 2022

AbstractWe used the observations from the east coast of the USA and model simulations to elicit marine atmospheric surface layer (MASL) processes that controlled the spatial variability of electromagnetic ducting conditions in the near‐shore (60 km) marine environment during CASPER‐East field campaign. The estimated evaporation duct height (EDH) showed an average decrease of ∼2.5 m over every 10 km distance from the shore. The surface layer stability conditions chiefly determined the duct heights. While the mean duct height remained ∼10 m under unstable conditions, deeper (>20 m) evaporation ducts were frequently evident (∼40% of the time) during stable MASL conditions, which were responsible for the observed near‐shore EDH variability. Episodes of warm offshore flow and advection of hot and humid air from the Gulfstream region created ideal environmental conditions for stable MASL development and thus deeper ducts over the coastal ocean. A detailed case study of warm and humid Gulfstream air advection over the cooler coastal ocean is presented to elucidate the temporal evolution of the surface layer stability and associated changes in the spatial distribution of the evaporation duct height.
Low Nitrogen Fixation Related to Shallow Nitracline Across the Eastern Indian Ocean
Authors: Sato Takuya , Shiozaki Takuhei , Hashihama Fuminori , Sato Mitsuhide , Murata Akihiko , Sasaoka Kosei , Umeda Shin‐ichiro , Takahashi Kazutaka 
Published: October 2022

AbstractThe eastern Indian Ocean (EIO) is characterized by oligotrophic surface water with abundant dust supply, and thus, this environment is considered to provide a favorable niche for cyanobacterial diazotrophs. However, direct measurements have reported low nitrogen fixation with the dominance of heterotrophic diazotrophs, suggesting that the EIO has unique geophysical features and nutrient supplies controlling diazotrophy, in contrast to those in the Atlantic and Pacific Oceans. In this study, we investigated the activity and community of diazotrophs across the EIO from the Bay of Bengal to the west of Australia. Low nitrogen fixation was observed broadly in the EIO (26.1–75.6 μmol N m−2 d−1), except in the west of Australia (82–286 μmol N m−2 d−1). Although the surface nitrate concentration was low in the EIO, the upward nitrate flux was higher because of the shallower nitracline than that in other oligotrophic oceans. This created widespread conditions with low aeFe:N (supply ratio of aerosol iron to nitrogen), resulting in low nitrogen fixation rates. NifH amplicon sequencing demonstrated the dominance of heterotrophic diazotrophs widely in the EIO, with spatial segregation from cyanobacterial diazotrophs (Trichodesmium, UCYN‐A1). In general, cyanobacterial diazotrophs were abundant in the surface waters of the Bay of Bengal and west of Australia with a high aeFe:N supply, whereas heterotrophic diazotrophs were dominant in other broad regions. This finding demonstrates that the shallow nitracline and associated high upward nitrate supply are key factors for the unique diazotrophy in the EIO.
Evaluating Single‐Collector Efficiencies of Colloid Deposition From Lagrangian Simulations: Geometric Models and Particle Release Scenarios
Authors: Xiong Xiaofeng , Yang Zhibing , Hu Ran , Chen Yi‐Feng 
Published: October 2022

AbstractSingle‐collector efficiency is of paramount importance in colloid filtration theory and widely used to represent the average filtration efficiency of a specific porous medium. In this work we present new formulations (unifying the stochastic and limiting trajectory cases) for efficient evaluation of the single‐collector efficiency with Lagrangian simulations in axisymmetric flow field for two commonly adopted particle‐releasing scenarios: from the envelope boundary (Happel sphere‐in‐cell) and from the upstream projected area (sphere‐in‐cylinder). We introduce an equivalent captured flux and define a capture indicator variable for each particle, to avoid calculation of local capture probability in previous studies. The single‐collector efficiencies obtained with the proposed formulations using particle trajectory simulations in axisymmetric flow field are in excellent agreement with full 3D simulation results, which validates our approach. The results are also compared with the Levich equation and published correlation equations. The differences between the two particle‐releasing scenarios are clarified and their impact on the single‐collector efficiency is quantified. The proposed axisymmetric simulation method can significantly reduce the computational time for obtaining single‐collector efficiency in comparison to 3D modeling approach, and can also be conveniently applied to studying particle transport in other practical scenarios involving axial symmetry, such as constricted tubes, impinging jet, stagnation‐point flow.
Evolving polarisation of infiltrating and alveolar macrophages in the lung during metastatic progression of melanoma suggests CCR1 as a therapeutic target
Authors: Tapmeier Thomas T. , Howell Jake H. , Zhao Lei , Papiez Bartlomiej W. , Schnabel Julia A. , Muschel Ruth J. , Gal Annamaria 
Published: October 2022

AbstractMetastatic tumour progression is facilitated by tumour associated macrophages (TAMs) that enforce pro-tumour mechanisms and suppress immunity. In pulmonary metastases, it is unclear whether TAMs comprise tissue resident or infiltrating, recruited macrophages; and the different expression patterns of these TAMs are not well established. Using the mouse melanoma B16F10 model of experimental pulmonary metastasis, we show that infiltrating macrophages (IM) change their gene expression from an early pro-inflammatory to a later tumour promoting profile as the lesions grow. In contrast, resident alveolar macrophages (AM) maintain expression of crucial pro-inflammatory/anti-tumour genes with time. During metastatic growth, the pool of macrophages, which initially contains mainly alveolar macrophages, increasingly consists of infiltrating macrophages potentially facilitating metastasis progression. Blocking chemokine receptor mediated macrophage infiltration in the lung revealed a prominent role for CCR2 in Ly6C+ pro-inflammatory monocyte/macrophage recruitment during metastasis progression, while inhibition of CCR2 signalling led to increased metastatic colony burden. CCR1 blockade, in contrast, suppressed late phase pro-tumour MR+Ly6C- monocyte/macrophage infiltration accompanied by expansion of the alveolar macrophage compartment and accumulation of NK cells, leading to reduced metastatic burden. These data indicate that IM has greater plasticity and higher phenotypic responsiveness to tumour challenge than AM. A considerable difference is also confirmed between CCR1 and CCR2 with regard to the recruited IM subsets, with CCR1 presenting a potential therapeutic target in pulmonary metastasis from melanoma.
Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma
Authors: Rauf Bushra , Khan Shahid Y. , Jiao Xiaodong , Irum Bushra , Ashfaq Ramla , Zehra Mubashra , Khan Asma A. , Naeem Muhammad Asif , Shahzad Mohsin , Riazuddin Sheikh , Hejtmancik J. Fielding , Riazuddin S. Amer 
Published: October 2022

AbstractTo delineate the genetic bases of primary congenital glaucoma (PCG), we ascertained a large cohort consisting of 48 consanguineous families. Of these, we previously reported 26 families with mutations in CYP1B1 and six families with LTBP2, whereas the genetic bases responsible for PCG in 16 families remained elusive. We employed next-generation whole exome sequencing to delineate the genetic basis of PCG in four of these 16 familial cases. Exclusion of linkage to reported PCG loci was established followed by next-generation whole exome sequencing, which was performed on 10 affected individuals manifesting cardinal systems of PCG belonging to four unresolved families along with four control samples consisting of genomic DNAs of individuals harboring mutations in CYP1B1 and LTBP2. The analyses of sequencing datasets failed to identify potential causal alleles in the 10 exomes whereas c.1169G > A (p. Arg390His) in CYP1B1 and c.3427delC (p.Gln1143Argfs*35) in LTBP2 were identified in the control samples. Taken together, next-generation whole exome sequencing failed to delineate the genetic basis of PCG in familial cases excluded from mutations in CYP1B1 and LTBP2. These data strengthen the notion that compound heterozygous coding variants or non-coding variants might contribute to PCG.
Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage
Authors: Shiozawa Jun , de Vega Susana , Yoshinaga Chiho , Ji Xang , Negishi Yoshifumi , Momoeda Masahiro , Nakamura Tomomi , Yoshida Hiroyuki , Kaneko Haruka , Ishijima Muneaki , Okada Yasunori 
Published: October 2022

AbstractDestruction of articular cartilage in osteoarthritis (OA) is initiated by depletion of the hyaluronan (HA)-aggrecan network, followed by degradation of the collagen fibrils. Previously, we reported the implications of HA-binding protein involved in HA depolymerization (HYBID), alias cell migration-inducing protein (CEMIP) and KIAA1199, for HA degradation. However, transmembrane protein 2 (TMEM2), which is ~ 50% homologous to HYBID, was discovered as another hyaluronidase, but their expression and regulation by OA chondrocytes remain elusive. Here we report that the absolute mRNA copy numbers of HYBID are significantly (7.1-fold) higher in OA cartilage than normal cartilage, whereas TMEM2 levels are not different between the groups. HA-degrading activity of cultured OA chondrocytes disappeared by siRNA-mediated knockdown of HYBID, but not TMEM2. HYBID expression was significantly up-regulated by treatment with interleukin-6 (IL-6) or tumor necrosis factor-α (TNF-α) and additively increased by the combined treatment. No significant changes in the TMEM2 expression were seen by the factors examined. IL-1α remarkably enhanced IL-6 production and increased HYBID expression when soluble IL-6 receptor was supplemented. These results demonstrate that in stark contrast to the constitutive expression of TMEM2 and its negligible HA-degrading activity, HYBID is overexpressed in OA cartilage and up-regulated by IL-6 and TNF-α in OA chondrocytes.
Ultrafast nanoscale exciton dynamics via laser-combined scanning tunneling microscopy in atomically thin materials
Authors: Mogi Hiroyuki , Arashida Yusuke , Kikuchi Ryusei , Mizuno Ryosuke , Wakabayashi Jun , Wada Naoki , Miyata Yasumitsu , Taninaka Atsushi , Yoshida Shoji , Takeuchi Osamu , Shigekawa Hidemi 
Published: October 2022

AbstractLong-term stable excitons, bound pairs of electrons and holes, in van der Waals materials were found to be handled at room temperature, paving the way to develop optoelectronic/photonic devices for future high-speed communication technology. To miniaturize and integrate such functions to achieve highly efficient excitonic devices, understanding and manipulation of exciton dynamics in the nanoscale structures is absolutely essential. Since the spatial resolution of the optical techniques, which have been mainly used in the research of this field, is limited to μm to several tens of nm, the introduction of new technology is strongly desired. Here, we demonstrate a method to probe and visualize neutral excitons using the laser-combined multiprobe scanning tunneling microscopy (STM) system. Ultrafast dynamics of excitons in the nanostructures produced in an in-plane WS2/WSe2 heterostructure, such as dynamics in the ps region of many-body effects under high density and spatial variation in the effect of local defects on lifetime, was successfully revealed with a spatial resolution of 1 nm order. This method is expected to accelerate research on exciton dynamics and the development of applications directly based on the experimental results of nanoscale.
Systemischer Lupus erythematodes und Lupusnephritis: neue Therapiestrategien
Authors: Weinmann-Menke Julia 
Published: October 2022

ZUSAMMENFASSUNGDer systemische Lupus erythematodes (SLE) ist eine Autoimmunerkrankung, welche nahezu jedes Organsystem befallen kann. Die Krankheitsmanifestationen sowie die Verläufe des SLE sind sehr heterogen, eine frühe Diagnosestellung und adäquate Therapie der meist jungen Patient*innen ist für die Langzeitprognose ausgesprochen relevant. Neben der klinischen Einschätzung können die im Jahr 2019 neu publizierten Klassifikationskriterien von EULAR/ACR (EULAR: European League Against Rheumatism; ACR: American College of Rheumatology) bei der Diagnosestellung unterstützend zur Hilfe genommen werden. Die Hauptursache für Morbidität und Mortalität der Patient*innen mit SLE ist die Entwicklung einer Lupusnephritis (LN), sodass hier eine frühe Diagnosestellung für die Prognose der Patient*innen unabdingbar ist. Im Mittelpunkt der Therapie steht das Erreichen einer vollständigen Remission bzw. zumindest das Erreichen einer niedrigen Krankheitsaktivität sowie das Vermeiden aktiver Krankheitsphasen, alles möglichst unter dem Verzicht des Einsatzes von Steroiden. Aufgrund der Heterogenität der Erkrankung sind häufig individualisierte Therapieanpassungen erforderlich. Neuere Erkenntnisse über die Pathomechanismen des SLE und der LN haben zur Entwicklung zielgerichteter Therapien („targeted therapies“) geführt, die zunehmend das Therapiespektrum für Patient*innen mit SLE erweitern.
Die Rollen und Aufgaben der Advanced Practice Nurse (APN) bei der Versorgung von erwachsenen Dialysepatient*innen
Authors: Mrozicka-Karcz Anna 
Published: October 2022

ZUSAMMENFASSUNGAngesichts der demografischen und epidemiologischen Veränderungen steigt die Lebenserwartung stetig an und die Bedürfnisse der Patient*innen bekommen eine immer größere Bedeutung. Gleichzeitig bringen die Krankheiten immer mehr chronischen Charakter hervor und der Bedarf an pflegerischer, individueller und vor allem komplexer Unterstützung für erkrankte Menschen nimmt zu. Diesbezüglich sind die Gesundheitsberufe mit neuen Rollen und damit verbundenen Befugnissen sowie Verantwortungsbereichen konfrontiert. Diese verlangen von Pflegefachkräften zunehmend theoretisches Wissen, spezialisierte und vertiefte Kenntnisse sowie geeignete Fertigkeiten ab – Fähigkeiten, die an einer Hochschule oder Universität erworben werden können. An dieser Stelle ist es wichtig zu erkennen, wie unerlässlich der Einsatz von akademisch ausgebildeten Expert*innen mit der Bezeichnung Advanced Practice Nurse (APN) ist, um die bestehenden sowie zukünftigen Herausforderungen bewältigen zu können. Besonders in speziellen Bereichen wie der Nierenersatztherapie ist die Anstellung einer APN von großer Bedeutung, da diese mit ihrer Expertise das gesamte Team und vor allem die Dialysepatient*innen unterstützen kann. Des Weiteren arbeitet eine APN individualisierte Behandlungsmethoden aus und etabliert diese in die Pflegepraxis, um Outcome- und Effizienzsteigerungen im Gesundheitssystem gewährleisten zu können.
Accommodating heterogeneity in brand loyalty estimation: application to the U.S. beer retail market
Authors: Irani-Kermani Roozbeh , Jaenicke Edward C. , Mirshani Ardalan 
Published: October 2022

AbstractThe assessment of consumer behavior in brand-choice models may be greatly influenced by accurately modeling and evaluating a brand-loyalty parameter. The most well-known approaches for estimating brand loyalty employ a household’s past purchase data and account for habit formation with a single smoothing parameter that indicates the weight assigned to households’ current decisions versus their distant shopping history. In this study, we present a method for estimating time-varying smoothing parameters for heterogeneous households. We estimate smoothing parameters for American households from 2014 to 2017 using Nielsen Homescan data for the US beer retail market. Using this more flexible method, we discover that the smoothing parameter varies significantly among households and time frames (for the same households). We next include a brand-loyalty index based on this approach into a brand-choice model of the American beer retail market, demonstrating that this new method improves estimation results.
Two decades of rice research in Indonesia and the Philippines: A systematic review and research agenda for the social sciences
Authors: Cuaton Ginbert P. , Delina Laurence L. 
Published: October 2022

AbstractWhile rice studies are abundant, they usually focus on macro-level rice production and yield data, genetic diversity, cultivar varieties, and agrotechnological innovations. Moreover, many of these studies are either region-wide or concentrated on countries in the Global North. Collecting, synthesizing, and analyzing the different themes and topic areas in rice research since the beginning of the 21st century, especially in the Global South, remain unaddressed areas. This study contributes to filling these research lacunae by systematically reviewing 2243 rice-related articles cumulatively written by more than 6000 authors and published in over 900 scientific journals. Using the PRISMA 2020 guidelines, this study screened and retrieved articles published from 2001 to 2021 on the various topics and questions surrounding rice research in Indonesia and the Philippines—two rice-producing and -consuming, as well as emerging economies in Southeast Asia. Using a combination of bibliometrics and quantitative content analysis, this paper discusses the productive, relevant, and influential rice scholars; key institutions, including affiliations, countries, and funders; important articles and journals; and knowledge hotspots in these two countries. It also discusses the contributions of the social sciences, highlights key gaps, and provides a research agenda across six interdisciplinary areas for future studies. This paper mainly argues that an interdisciplinary and comparative inquiry of potentially novel topic areas and research questions could deepen and widen scholarly interests beyond conventional natural science-informed rice research in Indonesia and the Philippines. Finally, this paper serves other researchers in their review of other crops in broader global agriculture.
Tribological performances of CuSn10Bi3 alloy containing MoSi2 and ferrophosphorus under starved lubrication
Authors: Yang Dongya , Li Jiajun , Zhao Gengrui , Wang Honggang , Li Zhenyu , Chen Shengsheng , Gao Gui , Zhang Guowei , Xu Hong 
Published: October 2022

The effects of molybdenum disilicide (MoSi2) and ferrophosphorus (FemPn) particles on the tribological properties of copper-tin bismuth (CuSn10Bi3) bimetallic bearing materials were studied in this paper. The samples of CuSn10Bi3 containing MoSi2 and/or FemPn were prepared by powder sintering technology and the metallographic structure of four kinds of self-lubricating copper alloy composite materials after sintering was observed. The tribological properties of the copper alloy composites under starved lubrication conditions were investigated and its worn surfaces and wear debris were discussed and analysed. The results show that the addition of MoSi2 and/or FemPn particles can effectively refine the grain size, optimise the grain boundary morphology, and improve the mechanical properties of the alloys. Under extreme working conditions, the hard particles reinforced copper-based alloy samples have better wear resistance and anti-seizure resistance. GRAPHICAL ABSTRACT