bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetic mapping of multiple metabolic traits identifies novel genes for adiposity, lipids and insulin secretory capacity in outbred rats
Authors: Lee Thu H , Crouse Wesley L. , Keele Gregory R , Holl Katie , Seshie Osborne , Tschannen Michael , Craddock Ann , Das Swapan K. , Szalanczy Alexandria M , McDonald Bailey , Grzybowski Michael , Klotz Jason , Sharma Neeraj K , Geurts Aron M , Key Chia-Chi Chuang , Hawkins Gregory , Valdar William , Mott Richard , Woods Leah C Solberg 
Published: October 2022

<p>Despite the successes of human genome-wide association studies, the causal genes underlying most metabolic traits remain unclear. We used outbred heterogeneous stock (HS) rats, coupled with expression data and mediation analysis, to identify quantitative trait loci (QTLs) and candidate gene mediators for adiposity, glucose tolerance, serum lipids, and other metabolic traits. Physiological traits were measured in 1519 male HS rats, with liver and adipose transcriptomes measured in over 410 rats. Genotypes were imputed from low coverage whole genome sequence. Linear mixed models were used to detect physiological and expression QTLs (pQTLs and eQTLs, respectively), employing both SNP- and haplotype-based models for pQTL mapping. Genes with cis-eQTLs that overlapped pQTLs were assessed as causal candidates through mediation analysis. We identified 14 SNP-based pQTLs and 19 haplotype-based pQTLs, of which 10 were in common. Using mediation, we identified the following genes as candidate mediators of pQTLs: <em>Grk5</em> for a fat pad weight pQTL on Chr1, <em>Krtcap3</em> for fat pad weight and serum lipids pQTLs on Chr6, <em>Ilrun </em>for a fat pad weight pQTL on Chr20 and <em>Rfx6 </em>for a whole pancreatic insulin content pQTL on Chr20. Furthermore, we verified <em>Grk5 </em>and <em>Ktrcap3 </em>using gene knock-down/out models, thereby shedding light on novel regulators of obesity. </p>
СОЗДАНИЕ «ЦИФРОВЫХ ДВОЙНИКОВ» В РАМКАХ ЦИФРОВОЙ ТРАНСФОРМАЦИИ ЭКОЛОГИЧЕСКОГО МОНИТОРИНГА
Authors: Валиев Всеволод Сергеевич , Иванов Дмитрий Владимирович , Хасанов Рустам Равилевич 
Published: October 2022

На примере оценки содержания тяжелых металлов в донных отложениях водных объектов предложен подход, обеспечивающий эффективную технологию хранения, сопровождения и оценки информации, получаемой в процессе мониторинга окружающей среды, а также алгоритм ее цифровизации с построением модели типа «цифровой двойник». Показано, что комплексное использование подобных моделей позволит в перспективе перейти к моделированию состояния природных объектов в целом.
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الصحابي الجليل خزيمة بن ثابت الانصاري ودوره العلمي في التأريخ الاسلامي ت:37هـ/658م
Authors: Abdel Janabi Mohamed Ibrahim , Al Teramshawi Kamal Ahmoud Abtan 
Published: October 2022

الحمد لله رب العالمين , والصلاة والسلام على سيد المرسلين محمد صلى الله عليه وسلم وعلى آله وصحبه اجمعين. أما بعد فقد بعث الله سبحانه وتعالى رسوله بالهدى ليظهر دينه بالحق ولو كره الكافرون , وقد خص الله سبحانه وتعالى اُناس كانوا يناصرونه بأموالهم وانفسم لإتمام رسالته , فهم من اوصل الدين إلينا ولولاهم لما عرف الناس شيئا عن القرآن الكريم وسنة الرسول ((r, وقد بين القرآن الكريم فضلهم في مواضع عدة وتواتر فضلهم في السنة النبوية وهم خير الناس وخير القرون كما نص ذلك في حديث رسول((r , وكان من هؤلاء الصحابي الجليل ذو الشهادتين خزيمة بن ثابت الاوسي الانصاري , فقد صحب النبي قرابة عشر سنوات وكانت له مواقف نبيلة و ادوار تكاد تكون فريدة من نوعها طوال المدة المذكورة , فقد حضر اوائل موقف الرسول((r في المدينة المنورة بعد ان منّ الله عليه بالإيمان الصادق ولم يقتصر دوره في عهد النبوة فقد تعدى ذلك ففي عهد الخلافة الراشدة , قد شرح الله صدره لمعرفة الحق في مواقف الفتن التي حصلت في اواخر تلك الحقبة التأريخية .
Podcasts in Libraries in the USA
Authors: Savitskaya Tatiana E. 
Published: October 2022

The article aims at analyzing the current podcasts usage practice in American libraries and identifying its goals, objectives, and the types of podcasts applied. In US libraries, podcasting is used for distance learning, servicing remote users, describing databases and new services, reviewing new books, broadcasting librarians’ interviews, guest lectures, readers’ conferences, etc.In the digital age, with its information dissemination capabilities, the rapid development of podcasting, as a new library service, is motivated by its convenience, mass access, lack of spatial restrictions, time savings, etc. The active spread of the podcast format, as a kind of Internet radio, indicates a certain “screen fatigue” that has formed among the mass user, as well as the further qualitative and quantitative growth of the library services mediatization carried out with the help of complex integrated technologies. The widespread usage of the service-oriented library model in the United States over the past two decades has popularized the use of online applications related to the accessible electronic environment.The complex nature of podcasts usage in libraries of various types, their genre and thematic diversity, autonomy in space and time, makes them a promising library service that is destined for a great future.
الأفعال الكلامية الإنكارية في سورة الأعراف - بعد التعديل
Authors: محمد عبد العزيز 
Published: October 2022

إنّ مفهوم (الأفعال الكلامية) لا يقتصر دوره فقط على ربط وإيصال المفاهيم والمعلومات إلى الجانب الآخر من المتلقين فحسب؛ بل على العكس من ذلك يقوم بدور أوسع وأكبر من ذلك بكثير؛ أي: يقوم بالاهتمام بمغزى الألفاظ اللغوية وتعابيرها، من خلال تحويل الأقوال المجردة والسطحية، إلى أفعال كلامية ذات معاني وسمات قصدية، يظهر مدلولها وأثرها على الواقع اللغوي.
والأفعال الكلامية تنطلق من منظور إيحائي غير قابلة أو خاضعة لمعيار التنظير اللفظي فقط، بل تقوم بدور بارز وفعّال في إنجاز وضعيات جديدة، بمعنى تغيير حالة الأشياء في الكون من خلال تحقيق فعل على أرض الواقع، أي: أنّ القوة الإنجازية قد تتعدد بحسب سياق المقام، ومقاصد المتكلم.
ويُعدُّ هذا البحث جهداً متواضعاً في مجال ربط القرآن الكريم بالدراسات اللغوية الحديثة، من خلال سورة الأعراف التي هي من أجمع سور القرآن الكريم في بلورة الأفعال الكلامية الإنكارية، من مقاصد ومعانٍ، ومن إنذار للمشركين، عن سوء عاقبة الشرك في الدنيا والآخرة.
لذا جاءت الأفعال الكلامية الإنكارية في هذه السورة تحديدًا لتبين مدى الإصرار على الجحود الذي جرى للرسلِ مع أقوامهم. وللوقوف على أهم المجالات التواصلية والعلمية في القرآن الكريم، من خلال الدلالة التداولية للأفعال الكلامية (الإنكارية) التي لها العلاقة الوثيقة بالأغراض التحاورية، والقوالب ذات الأبعاد التواصلية، وربطها بالدلائل والإثباتات الربانية.
An Exploration of Scientific Literacy on Physics Subjects within Phenomenon-based Experiential Learning
Authors: Santhalia Prima Warta , Yuliati Lia 
Published: October 2022

Abstract
Scientific literacy is the ability to involve yourself in problems related to science. This research explores students' scientific literacy skills in experiential learning based on phenomena on the concept of expansion. This research was conducted with a mix-method approach with an embedded experimental model design. The data were collected through scientific literacy tests (r = 0.53), and open-ended questions interviews with the students, then analyzed using the Mann-Whitney U-Test quantitatively, and using the Bybee (1997) assessment rubric qualitatively. Based on the results, it was found that the majority of students experienced an increase in their scientific literacy from the SI (Scientific Illiteracy) category (96.88%) into CSL (Conceptual Scientific Literacy) (46.88%). We concluded that phenomenon-based experiential learning was effective in improving students' scientific literacy. So, we need more effort to improve and increase students' scientific literacy skills by integrating scientific literacy competencies while implementing science learning in schools.
Sensor Technology for Opening New Pathways in Diagnosis and Therapeutics of Breast, Lung, Colorectal and Prostate Cancer
Authors: Roshani Saeed , Coccia Mario , Mosleh Melika 
Published: October 2022

This study analyzes the interaction between sensor research and technology and different types of cancer (breast, lung, colorectal, and prostate) with the goal of detecting new directions for improving diagnosis and therapeutics in medicine. This study develops an approach to computational scientometrics based on data from the Web of Science from the 1991 to 2021 period. The results of this analysis show the vital role of biosensors and electrochemical biosensors applied in breast cancer, lung cancer, and prostate cancer research. Instead, scientific research of optical sensors is developing main technological trajectories in breast, prostate, and colorectal cancer for improving diagnostics. Finally, oxygen sensor research has a main technological development in breast and lung cancer for new applications in breath analysis directed to treatment processes. Preliminary results presented here clearly illustrate the evolutionary paths of sensor research and technologies that have great potential for developing incremental and radical innovations in cancer diagnosis and therapies. These conclusions are, of course, tentative. There is a need for much more detailed research based on other aspects and factors for detecting stable technological trajectories that can foster the technology transfer of new sensor in cancer research for improving diagnosis and therapeutics, reducing, whenever possible, world-wide mortality of cancer in society.JEL Classification: I10, O30, O31, O32; O33. Doi: 10.28991/HIJ-2022-03-03-010 Full Text: PDF
The Impact of Digital Marketing vs. Traditional Marketing on Consumer Buying Behavior
Authors: Mehmeti-Bajrami Shpresa , Qerimi Fidan , Qerimi Arbëresha 
Published: October 2022

Objectives: This research aims to measure the impact of digital marketing vs. traditional marketing on consumer behavior by analyzing their motives and reasons related to the orientation and purchase of products or services through social media and identifying the differences in marketing strategies used depending on the demographics of respondents. Methods: The research was realized based on primary data. For the realization of the research objectives and questions, a quantitative method was used, where 400 citizens of Kosovo were a part of the research. Findings: Based on the ordinary least squares (OLS) model, it turned out that the two marketing types impact consumer buying behavior, but digital marketing turned out to be the indicator with the greatest impact on deciding to make purchases. Also, based on the t-test and ANOVA, there was no significant difference in using traditional and digital marketing types depending on demographic variables. Novelty/improvement:Through this research, businesses receive comments on the preferences of citizens for the marketing type and the possible offers depending on the preferences, as well as the impact of traditional and digital marketing on the purchasing behavior of consumers. Doi: 10.28991/HIJ-2022-03-03-08 Full Text: PDF
Remaja dan Warung Kopi pada Masa Pandemi Covid-19 (Studi Kasus di Gampong Meunasah Cut Kecamatan Nisam Kabupaten Aceh Utara)
Authors: Jannah Nurul , Rangkuty Rakhmadsyah Putra 
Published: October 2022

This research is entitled Youth and Coffee Shops during the Covid 19 Pandemic (Case Study in Gampong Meunasah Cut, Nisam District, North Aceh Regency). This study focuses on the causes of teenagers in Gampong Meunasah Cut to choose to gather in coffee shops during the Covid 19 pandemic and the impact of coffee shops on adolescents during the Covid 19 pandemic. This study uses Veblen's perspective of social change theory. Veblen sees technology as coloring the social system. Therefore, put forward the proposition that human behavior reflects technological and economic development. Veblen's statement implicitly requires the ability of technology to influence human behavior. If so, then the technology carries certain values and therefore is not value free in social life. The research method used in this research is a qualitative method using a descriptive approach. The results of this study indicate that the reason why teenagers in Gampong Meunasah Cut chose to gather at a coffee shop during the Covid 19 pandemic were (a) available free wifi internet network, (b) participating in online learning, and (c) adequate facilities. The impact of coffee shops on adolescents during the Covid 19 pandemic in Gampong Meunasah Cut is (a) it has an impact on education, (b) can control youth interactions, and (c) builds patterns of social interaction between teenagers and the community.Penelitian ini berjudul Remaja Dan Warung Kopi Pada Masa Pandemi Covid 19 (Studi Kasus di Gampong Meunasah Cut Kecamatan Nisam Kabupaten Aceh Utara). Penelitian ini mengfokuskan pada penyebab remaja di Gampong Meunasah Cut memilih berkumpul di warung kopi pada masa pandemi covid 19 dan dampak warung kopi terhadap remaja pada masa pandemi covid 19. Penelitian ini menggunakan teori perubahan sosial perspektif Veblen. Veblen melihat teknologi mewarnai tatanan sistem sosial. Karena itu, mengajukan preposisi bahwa perilaku manusia mencerminkan perkembangan teknologi dan ekonominya. Statement Veblen ini secara implisit mengsyaratkan kemampuan teknologi dalam mempengaruhi perilaku manusia. Jika demikian, maka teknologi itu membawa nilai-nilai tertentu dan karenanya tidak bebas nilai dalam kehidupan sosial. Metode penelitian yang digunakan dalam penelitian ini yaitu metode kualitatif dengan menggunakan pendekatan deskriptif. Hasil penelitian ini menunjukkan bahwa penyebab remaja di Gampong Meunasah Cut memilih berkumpul di warung kopi pada masa pandemi covid 19 adalah (a) tersedia jaringan internet wifi gratis, (b) mengikuti belajar daring, dan (c) tersedia fasilitas memadai. Dampak warung kopi terhadap remaja pada masa pandemi covid 19 di Gampong Meunasah Cut adalah (a) berdampak terhadap pendidikan, (b) dapat mengontrol pergaulan remaja, dan (c) membangun pola interaksi sosial antara sesama remaja dan masyarakat.
KEKEJAMAN KKB PAPUA YANG MELANGGAR HAM
Authors: Septiadi Muhammad Andi , Sofa Nazzira Gahitsya , Syarah Siti , Shakira Wanda 
Published: October 2022

The number of cases of violations of Human Rights (HAM) committed by a group of terrorists in Papua (KKB) is certainly a cause of fear for Papuans and other Indonesians. If it is not stopped, there will be more casualties caused by this group. The case of human rights violations committed by the Papuan KKB is still a topic of discussion among the wider community. We know that the role of the Government, TNI and Polri is very important in overcoming this conflict. Here we will discuss about the cruelty of the Papuan KKB which violates human rights. The reason is none other than to provide input to the party who is obliged to resolve this case.Banyaknya kasus pelanggaran Hak Asasi Manusia (HAM) yang dilakukan oleh sekelompok teroris di Papua (KKB) ini tentunya membuat ketakutan tersendiri bagi warga Papua dan masyarakat Indonesia lainnya. Jika tidak dihentikan maka akan semakin banyak korban jiwa yang diakibatkan oleh sekelompok tersebut. Kasus pelanggaran HAM yang dilakukan KKB Papua ini masih saja menjadi perbincangan dikalangan masyarakat luas. Kita tahu bahwasannya peran Pemerintah, TNI dan Polri sangat penting dalam menanggulangi konflik ini. Disini kami akan membahas mengenai Kekejaman KKB Papua Yang Melanggar HAM. Adapun alasannya tidak lain untuk memberi masukan kepada pihak yang berkewajiban untuk menyelesaikan kasus ini.
PENGARUH PERCEIVED OF RISK (PERSEPSI RISIKO) TERHADAP MINAT BELI ONLINE
Authors: Nadia Nadia , Ritonga Nursakinah 
Published: October 2022

This study aims to examine the influence of perceived of risk on the online buying interest of the people of Dusun 1 Tambon Tunong Village, Dewantara District, North Aceh Regency. This research was conducted in Hamlet 1 of Tambon Tunong Village, Dewantara District, North Aceh Regency. This study used primary data in the form of questionnaires that were distributed to the people of Dusun 1 Tambon Tunong Village, Dewantara District, North Aceh Regency who made online purchases. The data analysis methods used are instrument tests and classical assumption tests as well as simple linear regression tests using the help of SPSS version 26 software. The results of the partial test showed that the perceived of risk had a positive and significant effect on the online buying interest of the people of Dusun 1 Tambon Tunong Village, Dewantara District, North Aceh Regency.
Le Sari vert, un plaidoyer pour les femmes au-delà de l’océan Indien
Authors: Rey Mimoso-Ruiz Bernadette 
Published: October 2022

Bien que Le Sari vert se présente comme un monologue masculin, il n’en est pas moins un plaidoyer pour les femmes, une illustration de la maltraitance au nom de la virilité dans un contexte que l’on ne peut circonscrire uniquement dans la société mauricienne.
Dans le projet de cette étude, à partir de la problématique centrée sur la monstruosité dans ses manifestations et ses paramètres psychologiques, seront examinées les composantes relevant spécifiquement de la culture et de la société mauricienne, de son héritage indien dans la conception du féminin, de l’influence d’une religion hiérarchisée ainsi que les éléments linguistiques en usage chez Ananda Devi qui leur octroient une dimension ouverte sur l’Occident au service d’une cause tristement universelle.
An Interview with Ananda Devi
Authors: Czarnowus Anna , Mamet-Michalkiewicz Marta 
Published: October 2022

An interview with Ananda Devi, which was conducted by Associate Professor Anna Czarnowus and Dr Marta Mamet-Michalkiewicz in 2019. The author talks about her own multilingualism, the novels where she dicusses violence, including sexual violence, her literary inspirations, the symbolism of her texts, female anger and feminism, the cultural meaning of cooking, and her novel 'The Living Days'.
PENGARUH MANAJERIAL DAN KEBIJAKAN PERIODESASI KEPALA SEKOLAH TERHADAP DISIPLIN KERJA GURU SEKOLAH DASAR DI KECAMATAN JAPARA
Authors: Suhari Suhari 
Published: October 2022

Keberadaan guru dalam operasional Pendidikan sangat dominan peranannya. Karena begitu pentingnya maka disiplin kerja guru harus baik. Banyak faktor yang dapat mempengaruhi disiplin kerja guru diantaranya manjerial kepala sekolah dan kebijakan periodesasi kepala sekolah. Maka dari itu, fokus penelitian ini adalah ingin mengetahui dan menganalisis pengaruh manajerial kepala sekolah dan kebijakan periodesasi kepala sekolah terhadap disiplion kerja guru. Metode penelitian yang digunakan adalah metode deskriptif dan verifikatif, dengan teknik pengumpulan data menggunakan angket skala likert, terhadap 60 orang guru. Pengolahan hasil penelitian menggunakan teknik analisis regresi. Uji signifikansi menggunakan uji-F. Hasil penelitian menunjukkan bahwa: (1) Terdapat pengaruh positif manajerial kepala sekolah terhadap disiplin kerja guru. (2) Terdapat pengaruh positif kebijakan periodesasi kepala sekolah terhadap disiplin kerja guru. (3) Terdapat pengaruh positif manajerial kepala sekolah dan kebijakan periodesasi kepala sekolah dan tidak signifikan secara simultan terhadap disiplin kerja guru. Sehubungan dengan pengaruh periodesasi kepala sekolah dan kebijakan periodesasi kepala sekolah terhadap disiplin guru tidak signifikan, sehingga untuk meningkatkan disiplin kerja guru dapat dilakukan melalui peningkatan manajerial kepala sekolah dan memaksimalkan kebijakan periodesasi kepala sekolah. Untuk meningkatkan manajerial kepala sekolah masih ada kendala pada dimensi tepat cepat menyelesaikan masalah. Oleh karena itu penulis menyarankan agar: (1) Kepala sekolah senantiasa meningkatkan kapasitas dirinya terkait manajerial kepala sekolah untuk meningkatkan disiplin kerja guru. (2) Kebijakan periodesasi kepala sekolah harus didukung semua pihak agar disiplin kerja guru terjaga sehingga dapat mewujudkan tata kelola sekolah sesuai dengan ,tujuan pendidikan.
Feasibility of automated in-vehicle technologies on volunteers’ driving performance
Authors: Classen Sherrilene , Winter Sandra , Wei Jiajun , Jeghers Mary , Rogers Jason , Giang Wayne 
Published: October 2022

BACKGROUND: Automated in-vehicle technologies, specifically in-vehicle information systems (IVIS) and advanced driver assistance systems (ADAS), are increasingly common in today’s cars. Previous studies illustrate benefits of using IVIS and ADAS to improve safety, convenience, and comfort in healthy older drivers. However, research is sparse on the feasibility of such technologies for medically at-risk drivers, such as those with Parkinson’s disease (PD). OBJECTIVE: This study enrolled healthy volunteer drivers to examine the feasibility of the procedures and measures for evaluating the effects of IVIS and ADAS on their driving performance. METHODS: During this feasibility study researchers compared drives completed with and without support of IVIS and ADAS, as participants drove a 2019 Toyota Camry XLE. The test vehicle was equipped with IVIS, ADAS, cameras, a telematics system, and sensors. Participants drove the road course supervised by a Driver Rehabilitation Specialist (DRS). RESULTS: Overall study procedures and vehicle equipment were feasible and provided sufficient data collection for measuring the impact of IVIS and ADAS on driving performance. Data observation by the DRS combined with data captured from cameras and telematics, facilitated comparisons to increase data reliability and validity. CONCLUSIONS: Feasibility study findings informed a randomized clinical trial, examining the use of IVIS and ADAS technologies as an intervention to support drivers with Parkinson’s disease.