bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of electrical resistance and dielectric constant of Boron Nitride and Banana fiber reinforced epoxy polymer matrix composite
Authors: Salunke Dinesh R , Gopalan Venkatachalam 
Published: September 2022

Nowadays, high thermal conductive and good electrical insulating materials gain attention for compact and sustainable design in power electronics instruments like transformers, switches, cables. To cater for these needs, Boron Nitride (BN)/Banana Fiber (BF)/Epoxy based polymer composite is proposed which exhibits good electrical resistance and low dielectric constant. Banana fiber is chosen as it contains few lumens among the fillers and offers good mechanical strength. Boron Nitride and Banana fiber are reinforced with epoxy resin to form highly insulating polymer matrix composite material. Various samples are fabricated, containing 1/3/5 μm BN particle size, 1/3/5 wt % of BN and 0/2/4 wt % of BF derived from Response surface methodology based Box Behnken Design model using design of experiments approach. Further, Analysis of Variance is performed to obtain optimized levels of parameters using regression equation in MINITAB software. Also, experimental results and optimized results are compared leading to error analysis. High resistance of 346.68 Giga-ohms (86.67 ×109 Ω-m resistivity) and minimum dielectric constant of 1.143 are obtained for combination of 3 wt % of BN, 2 wt % of BF and particle size of 3 μm which is considerable for good insulation purpose.
Career Adaptability Development in the School-To-Work Transition
Authors: Fu Chuhang , Cai Yang , Yang Qiandong , Pan Guoqiang , Xu Dezhen , Shi Wendian 
Published: September 2022

The development pattern of career adaptability has an important influence on individual mental health and career outcomes. Based on career construction theory, our study explored the development characteristics of the career adaptability of college students during the school-to-work transition and discussed how the notions of future work selves and core self-evaluation affect the development trajectories and development patterns of career adaptability. Our study investigated 429 college graduates at an interval of 6 months over the course of 1 year. The results indicated that the graduates had a positive career adaptability trajectory during the school-to-work transition. There were three different development patterns: rapid growth group, growth group, and stationary group. Future work selves predicted career adaptability positively and dynamically. A higher core self-evaluation predicted a higher initial level of career adaptability and a slower development speed. Our study has important implications for enriching career construction theory and career counseling practice.
Fluoroscopic Evaluation of the Role of Syndesmotic Injury in Lateral Ankle Instability in a Cadaver Model
Authors: Bhimani Rohan , Sato Go , Saengsin Jirawat , Lubberts Bart , Waryasz Gregory , DiGiovanni Christopher W. , Guss Daniel 
Published: September 2022

Background: There is a high prevalence of concomitant lateral ankle ligament injuries and syndesmotic ligamentous injuries. However, it is unclear whether syndesmotic ligaments directly contribute toward the stability of the lateral ankle. Therefore, the aim of this study was to fluoroscopically evaluate the role of the syndesmotic ligaments in stabilizing the lateral ankle. Methods: Twenty-four cadaveric specimens were divided into 3 groups and fluoroscopically evaluated for lateral ankle stability with all syndesmotic and ankle ligaments intact and then following serial differential ligamentous transection. Group 1: (1) anterior talofibular ligament (ATFL), (2) calcaneofibular ligament (CFL), and (3) posterior talofibular ligament (PTFL). Group 2: (1) anterior inferior tibiofibular ligament (AITFL), (2) interosseous ligament (IOL), (3) posterior inferior tibiofibular ligament (PITFL), (4) ATFL, (5) CFL, and (6) PTFL. Group 3: (1) AITFL, (2) ATFL, (3) CFL, (4) IOL, (5) PTFL, and (6) PITFL. At each transection state, 3 loading conditions were used: (1) anterior drawer test performed using 50 and 80 N of direct force, (2) talar tilt <1.7 Nm torque, and (2) lateral clear space (LCS) <1.7 Nm torque. These measurements were in turn compared with those of the stressed intact ligamentous state. Wilcoxon rank-sum test was used to compare the findings of each ligamentous transection state to the intact state. A P value <.05 was considered statistically significant. Results: The lateral ankle remained stable after transection of all syndesmotic ligaments (AITFL, IOL, PITFL). However, after additional transection of the ATFL, the lateral ankle became unstable in varus and anterior drawer testing conditions ( P values ranging from .036 to .012). Lateral ankle instability was also observed after transection of the ATFL and AITFL in varus and anterior drawer testing conditions ( P values ranging from .036 to .012). Subsequent transection of the CFL and PTFL worsened the lateral ankle instability. Conclusion: Our findings suggest that isolated syndesmosis disruption does not result in lateral ankle instability. However, the lateral ankle became unstable when the syndesmosis was injured along with ATFL disruption. Clinical Relevance: When combined with ATFL release, disruption of the syndesmosis appeared to destabilize the lateral ankle.
First-Line Immunochemotherapy Versus Palliative Chemotherapy Plus Definitive Radiation Therapy for de novo Metastatic Nasopharyngeal Carcinoma: A Matched Cohort Study
Authors: Yang Zhen-Chong , Liu Ting , Chen Yan-Zhou , Guo Chun-Yan , Liu Li-Ting , Liu Sai-Lan , Chen Qiu-Yan , Mai Hai-Qiang , Guo Shan-Shan 
Published: September 2022

Background The combined use of immune checkpoint inhibitors (ICIs) with palliative chemotherapy (PCT) is a promising first-line treatment for de novo metastatic nasopharyngeal carcinoma (mNPC). However, the efficacy of ICIs with PCT vs PCT with definitive radiation therapy (DRT) remain unclear. Methods Patients with mNPC who received first-line immunochemotherapy (ICI + PCT) or PCT + DRT were included. Propensity score matching (PSM) was applied to balance potential confounders between patients who did and did not undergo DRT (at a ratio of 1:1). Progression free survival (PFS) and overall survival (OS) were compared between the 2 groups using a log-rank test and Cox proportional hazard model. Results Among all participants, 149 received ICI + PCT. After PSM, 149 patients were included in the PCT + DRT group. First-line immunochemotherapy was associated with significantly improved PFS (median 9.0 months vs 12.0 months, P < .001) and OS (median 12.5 months vs 19.9 months, P < .001). Subgroup analysis revealed that tumor response to immunochemotherapy, metastatic organs, and number of metastatic sites potentially affected the efficacy of DRT after first-line immunochemotherapy. Conclusion Compared with PCT + DRT, first-line immunochemotherapy was associated with improved PFS and OS in patients with mNPC but not in patients with unfavorable tumor response and metastasis involving the liver, distant nodes, or multiple sites.
Correction of high astigmatism with toric intraocular lens in eyes with corneal transplant
Authors: Devebacak Ali , Degirmenci Cumali , Barut Selver Ozlem , Palamar Melis , Egrilmez Sait 
Published: September 2022

Objectives To evaluate the results of toric intraocular lens (IOL) implantation during cataract surgery in eyes with high regular astigmatism associated with prior penetrating keratoplasty (PK). Methods A retrospective data analysis of patients with prior PK, who underwent uncomplicated cataract surgery with hydrophobic toric single piece IOL (EyeCryl Toric®, Biotech Vision Care, Luzern, Switzerland). Results A total of 18 eyes of 18 patients were included in the study. The mean age was 53.4 ± 12.4 (25–70) years. The mean follow-up period was 15.5 (4–24) months. The mean best corrected visual acuity (BCVA) significantly increased from 1.36 ± 1.0 logMAR to 0.31 ± 0.17 logMAR (p < .001) pre- and post-operative 4 weeks, respectively. There was no significant change in mean BCVA during follow-up; mean BCVA was 0.32 ± 0.17 logMAR at the last visit. The mean pre-operative topographic astigmatism was 6.52 ± 1.80 diopters (D). The mean manifest refraction astigmatism was decreased from 6.55 ± 1.62 D to 2.80 ± 1.43 D (p˂0.001). The mean Surgically induced astigmatism (SIA) was 3.74 ± 0.77 D according to vector analysis. There was no patient with graft rejection or failure, the mean endothelial cell loss rate was 12.75 ± 3.76% (7–17%). There was no patient requiring IOL reposition. Conclusions Toric IOL implantation during cataract surgery provides an option to correct astigmatism in post-PK eyes with high regular astigmatism. When appropriate patients are selected it is a safe method to achieve significant improvements in visual acuity and astigmatism.
Histoplasma capsulatum, Toxoplasma gondii, Bartonella henselae and Bartonella clarridgeiae coinfections in an indoor-only Siamese cat
Authors: Fuller Alexandra , Černá Petra , Jost Haley , Williams Maggie , Shropshire Sarah , Lappin Michael R 
Published: September 2022

Case summary A 6-year-old male castrated Siamese cat was referred for acute-onset blindness and mydriasis. Physical examination revealed serous retinal detachment with panuveitis and systemic hypertension. Abdominal ultrasound showed suspected dilation of the cisterna chyli and abdominal lymphadenopathy. Aspirates of mesenteric lymph nodes revealed intrahistiocytic yeast organisms with mild-to-moderate pyogranulomatous inflammation. Fungal culture and ITS1 sequencing of the lymph node aspirates confirmed infection with Histoplasma capsulatum. PCR performed on whole blood was positive for Bartonella henselae and Bartonella clarridgeiae, and Toxoplasma gondii IgG and IgM antibodies were detected in serum. The cat was prescribed prednisolone (0.5 mg/kg PO q24h), itraconazole (10 mg/kg PO q24h), clindamycin (13 mg/kg PO q12h), amlodipine (0.625 mg PO q24h), prednisolone acetate 1% drops (q6h) and ophthalmic lubricant for both eyes (q6h). The cat was doing well at home after 2 weeks of prednisolone, itraconazole and clindamycin administration, and no abnormalities were detected on repeat abdominal ultrasound 3 months later. The retinal detachment showed mild-to-moderate improvement at that time, but vision was not regained. Relevance and novel information This is the first report of coinfection of H capsulatum, T gondii, B henselae and B clarridgeiae in an indoor-only cat living in a H capsulatum non-enzootic area with no known travel history.
Effect of Preoperative Joint Space Width on Lateral Meniscal Allograft Transplantation: Outcomes at Midterm Follow-up
Authors: Lee Dhong Won , Lee Dong Ryun , Kim Min Ah , Lee Joon Kyu , Kim Jin Goo 
Published: September 2022

Background: It remains unclear whether lateral joint space narrowing without severe cartilage loss before meniscal allograft transplantation (MAT) affects clinical outcomes and graft extrusion. Hypothesis: Patients with greater preoperative joint space narrowing would show more graft extrusion, more osteoarthritis progression, and worse clinical outcomes than would those with less narrowing. Study Design: Case-control study; Level of evidence, 3. Methods: We retrospectively evaluated 61 patients who underwent lateral MAT and had a minimum follow-up of 4 to 5 years. The median preoperative joint space width (JSW) on Rosenberg view radiographs was used to classify patients into those with less joint space narrowing (JSW ≥3 mm; group A) and greater joint space narrowing (JSW <3 mm; group B). We compared differences between groups in terms of graft extrusion and articular cartilage loss (modified Outerbridge grade ≥3) on 1-year postoperative magnetic resonance imaging (MRI) scans and changes in JSW and clinical outcomes at the last follow-up. Results: There were 31 patients in group A and 30 patients in group B; the mean follow-up time for all patients was 64.4 ± 10.3 months. All patients showed a significant preoperative to postoperative improvement in outcome scores ( P < .001 for all). The mean preoperative JSW was 3.8 ± 0.9 mm in group A and 2.3 ± 0.4 mm in group B ( P < .001). In group B, there was more graft extrusion on postoperative MRI scans (3.0 ± 0.9 vs 1.9 ± 0.6 mm, respectively; P < .001) and a higher proportion of patients with pathological graft extrusion at final follow-up (43.3% vs 12.9%, respectively; P = .011) compared with group A. At 1 year postoperatively, cartilage loss grade ≥3 was observed at the lateral femoral condyle in 3.2% and 20.0% of patients in groups A and B ( P = .053), respectively, and at the lateral tibial plateau in 3.2% and 30.0% of patients ( P = .006), respectively. There were moderate correlations between graft extrusion and preoperative absolute JSW ( r = –0.471; P < .001) and preoperative relative JSW ( r = –0.428; P = .001). Conclusion: Patients with less preoperative joint space narrowing had less graft extrusion and cartilage loss on 1-year postoperative MRI scans, as well as better radiological and clinical outcomes at midterm follow-up, compared with patients with greater preoperative narrowing.
Building the 2022 Diabetes Technology Practice Competencies Using Modified Delphi Methodology
Authors: Hughes Allyson S. , Albanese-O’Neill Anastasia , Seley Jane Jeffrie , Yehl Kirsten , Scalzo Patty , Rinker Joanne , Patil Shivajirao P. 
Published: September 2022

Purpose: The purpose of this study was to construct professional competencies for diabetes technology use in various care settings reflecting the mission of the Association of Diabetes Care & Education Specialists (ADCES). Method: ADCES convened a core team of nationally representative diabetes technology experts to develop professional competencies specifically related to diabetes technology use. A modified Delphi methodology, which comprised 4 rounds, was used for consensus development among these experts. First, experts developed and arrived at a consensus on the initial draft of competencies. They also identified health care professionals and staff essential for effective technology integration in various diabetes care settings. A survey was completed by diabetes technology experts that are members of ADCES. Next, a multidisciplinary focus group was conducted to gain feedback. Finally, the edited competencies were distributed via survey for feedback by diabetes technology experts from various disciplines. Results: One hundred four diabetes technology experts in the United States participated in the final survey, representing various health care professions and clinical settings. A final set of 94 competencies across 7 domains was determined. Conclusion: Modified Delphi methodology is an effective way to utilize multidisciplinary expertise to develop diabetes technology-related competencies for diabetes care professionals and staff in a variety of settings. These competencies align with the mission of ADCES to empower diabetes care and education specialists to expand the horizons of innovative education, management, and support.
Intraoperative CT-guided navigation versus fluoroscopy for percutaneous pedicle screw placement in 192 patients: a comparative analysis
Authors: La Rocca Giuseppe , Mazzucchi Edoardo , Pignotti Fabrizio , Nasto Luigi Aurelio , Galieri Gianluca , Olivi Alessandro , De Santis Vincenzo , Rinaldi Pierluigi , Pola Enrico , Sabatino Giovanni 
Published: September 2022

Abstract
Background
Percutaneous pedicle screw (PPS) placement is a key step in several minimally invasive spinal surgery (MISS) procedures. Traditional technique for PPS makes use of C-arm fluoroscopy assistance (FA). More recently, newer intraoperative imaging techniques have been developed for PPS, including CT-guided navigation (CTNav). The aim of this study was to compare FA and CTNav techniques for PPS with regard to accuracy, complications, and radiation dosage.

Materials and methods
A total of 192 patients with degenerative lumbar spondylolisthesis and canal stenosis who underwent MISS posterior fusion ± interbody fusion through transforaminal approach (TLIF) were retrospectively reviewed. Pedicle screws were placed percutaneously using either standard C-arm fluoroscopy guidance (FA group) or CT navigation (CTNav group). Intraoperative effective dose (ED, mSv) was measured. Screw placement accuracy was assessed postoperatively on a CT scan using Gertzbein and Robbins classification (grades A–E). Oswestry disability index (ODI) and visual analog scale (VAS) scores were compared in both groups before and after surgery.

Results
A total of 101 and 91 procedures were performed with FA (FA group) and CTNav approach (CTNav group), respectively. Median age was 61 years in both groups, and the most commonly treated level was L4–L5. Median ED received from patients was 1.504 mSv (0.494–4.406) in FA technique and 21.130 mSv (10.840–30.390) in CTNav approach (p < 0.001). Percentage of grade A and B screws was significantly higher for the CTNav group (96.4% versus 92%, p < 0.001), whereas there were 16 grade E screws in the FA group and 0 grade E screws in the CTNav group (p < 0.001). A total of seven and five complications were reported in the FA and CTNav group, respectively (p = 0.771).

Conclusions
CTNav technique increases accuracy of pedicle screw placement compared with FA technique without affecting operative time. Nevertheless, no significant difference was noted in terms of reoperation rate due to screw malpositioning between CTNav and FA techniques. Radiation exposure of patients was significantly higher with CTNav technique.
Level of Evidence: Level 3.
Intron size minimisation in teleosts
Authors: Jakt Lars Martin , Dubin Arseny , Johansen Steinar Daae 
Published: September 2022

Abstract
Background
Spliceosomal introns are parts of primary transcripts that are removed by RNA splicing. Although introns apparently do not contribute to the function of the mature transcript, in vertebrates they comprise the majority of the transcribed region increasing the metabolic cost of transcription. The persistence of long introns across evolutionary time suggests functional roles that can offset this metabolic cost. The teleosts comprise one of the largest vertebrate clades. They have unusually compact and variable genome sizes and provide a suitable system for analysing intron evolution.

Results
We have analysed intron lengths in 172 vertebrate genomes and show that teleost intron lengths are relatively short, highly variable and bimodally distributed. Introns that were long in teleosts were also found to be long in mammals and were more likely to be found in regulatory genes and to contain conserved sequences. Our results argue that intron length has decreased in parallel in a non-random manner throughout teleost evolution and represent a deviation from the ancestral state.

Conclusion
Our observations indicate an accelerated rate of intron size evolution in the teleosts and that teleost introns can be divided into two classes by their length. Teleost intron sizes have evolved primarily as a side-effect of genome size evolution and small genomes are dominated by short introns (<256 base pairs). However, a non-random subset of introns has resisted this process across the teleosts and these are more likely have functional roles in all vertebrate clades.
Silicon enhances the drought resistance of peach seedlings by regulating hormone, amino acid, and sugar metabolism
Authors: Gao Huaifeng , Yu Wenying , Yang Xiaoqing , Liang Jiahui , Sun Xiwu , Sun Maoxiang , Xiao Yuansong , Peng Futian 
Published: September 2022

Abstract
Background
Drought is one of the main concerns worldwide and restricts the development of agriculture. Silicon improves the drought resistance of plants, but the underlying mechanism remains unclear.

Results
We sequenced the transcriptomes of both control and silicon-treated peach seedlings under drought stress to identify genes or gene networks that could be managed to increase the drought tolerance of peach seedlings. Peach (Prunus persica) seedlings were used to analyse the effects of silicon on plant growth and physiological indexes related to drought resistance under drought stress. The results showed that silicon addition improved the water use efficiency, antioxidant capacity, and net photosynthetic rate, inhibition of stomatal closure, promoted the development of roots, and further regulated the synthesis of hormones, amino acids and sugars in peach seedlings. A comparative transcriptome analysis identified a total of 2275 genes that respond to silicon under drought stress. These genes were mainly involved in ion transport, hormone and signal transduction, biosynthetic and metabolic processes, stress and defence responses and other processes. We analysed the effects of silicon on the modulation of stress-related hormonal crosstalk and amino acid and sugar metabolism. The results showed that silicon promotes zeatin, gibberellin, and auxin biosynthesis, inhibits the synthesis of abscisic acid, then promote lateral root development and inhibit stomatal closure, and regulates the signal transduction of auxin, cytokinin, gibberellin and salicylic acid. Silicon also regulates the metabolism of various amino acids and promotes the accumulation of sucrose and glucose to improve drought resistance of peach seedlings.

Conclusions
Silicon enhanced the drought resistance of peach seedlings by regulating stress-related hormone synthesis and signal transduction, and regulating amino acid and sugar metabolism.