bluuebunny/crossref_metadata_2025_split huggingface dataset:
High‐Performance Strain of Lead‐Free Relaxor‐Ferroelectric Piezoceramics by the Morphotropic Phase Boundary Modification
Authors: Li Tangyuan , Liu Chang , Shi Peng , Liu Xiao , Kang Ruirui , Long Changbai , Wu Ming , Cheng Shaodong , Mi Shaobo , Xia Yuanhua , Li Linglong , Wang Dong , Lou Xiaojie 
Published: June 2022

AbstractBismuth sodium titanate (BNT)‐based lead‐free piezoceramics are promising for replacing lead‐based piezoceramics in piezoelectric actuators due to their large strains. However, achieving low‐hysteresis large‐strain BNT‐based ceramics over a broad temperature range is challenging, owing to the complexity of the composition design and phase transformation. Herein, a lead‐free relaxor‐ferroelectric (1−x)Bi0.47Na0.47Ba0.06TiO3‐xK0.47Na0.47Li0.06Nb0.99Sb0.01O2.99 system (BNBT‐KNLNS) near the morphotropic phase boundary (MPB), achieved by phase‐field simulations and rational composition design (i.e., BNBT with the MPB as the base and the ferroelectric phase of KNLNS as the dopant) is reported. This ceramic exhibits large strains (0.32–0.51%) and low strain hysteresis (11.1–59.9%) over a wide temperature range (25–125 °C), outperforming many state‐of‐the‐art lead‐free piezoceramics. A small fraction of ferroelectric states embedded in the relaxor matrix is experimentally observed, where these states act as seeds, facilitating the reversible relaxor‐to‐ferroelectric transition. In addition, the MPB composition with low energy barriers yields large strain responses, owing to the easy polarization reversal and extension. Consequently, low‐hysteresis large strains are obtained over a broad temperature range. This work provides a novel design route for discovering high‐performance piezoceramics for actuator applications.
Improving the Stability of Silicon Nanowires During Photoelectrochemical Hydrogen Generation with Zinc 1T‐Phase Molybdenum Disulfide
Authors: Younan Sabrina M. , Li Zhida , Fairchild Michael P. , Williams Nicholas B. , Huang Yichao , Gu Jing 
Published: June 2022

AbstractSemiconductor photoelectrodes directly convert sunlight into stored chemical energy. In photoelectrochemical (PEC) devices, this photoconversion process relies on the junction between the semiconductor and catalyst to drive charge separation and generate electron/hole charge carriers. The growth of native oxides (SiOx) on the surface of semiconductors during device operation induces charge carrier recombination and photodegradation, which limit the operation lifetime of PEC devices. Likewise, the commercialization of photoelectrochemical devices is hindered by the use of expensive, rare precious metal catalysts such as platinum to enhance hydrogen evolution kinetics. This work demonstrates how drop casting zinc 1T‐phase molybdenum disulfide (Zn 1T‐MoS2) onto silicon nanowires (SiNWs) generates an interface that overcomes these challenges. This Zn 1T‐MoS2/SiNWs junction drives hydrogen evolution under acidic conditions (0.5 M H2SO4) comparably to platinum‐modified SiNWs (Pt/SiNWs) with a positive overpotential of 164 mV at 10 mA cm−2 and low Tafel slope of 42 mV dec−1. Compared to the bare SiNWs, the Zn 1T‐MoS2/SiNWs junction retains roughly 66% more photocurrent density and reduces SiOx growth by 16% after 24 h of continuous electrolysis. By developing a deep understanding of the catalyst‐semiconductor interface, photoelectrochemical devices may be effectively designed to maintain their stability over a lifetime of operation.
Exciton Diffusion and Annihilation in Nanophotonic Purcell Landscapes
Authors: Raziman T. V. , Visser C. Peter , Wang Shaojun , Gómez Rivas Jaime , Curto Alberto G. 
Published: June 2022

AbstractExcitons spread through diffusion and interact through exciton–exciton annihilation. Nanophotonics can counteract the resulting decrease in light emission. However, conventional enhancement treats emitters as immobile and non‐interacting. It neglects exciton redistribution between regions with different enhancements and the increase in non‐radiative decay at high exciton densities. Here, the authors went beyond the localized Purcell effect to exploit exciton dynamics and turn their typically detrimental impact into additional emission. As interacting excitons diffuse through optical hotspots, the balance of excitonic and nanophotonic properties leads to either enhanced or suppressed photoluminescence. The dominant enhancement mechanisms are identified in the limits of high and low diffusion and annihilation. Diffusion lifts the requirement of spatial overlap between excitation and emission enhancements, which are harnessed to maximize emission from highly diffusive excitons. In the presence of annihilation, improved enhancement is predicted at increasing powers in nanophotonic systems dominated by emission enhancement. The guidelines are relevant for efficient and high‐power light‐emitting diodes and lasers tailored to the rich dynamics of excitonic materials such as monolayer semiconductors, perovskites, or organic crystals.
Novel Therapeutic Strategy for Bacteria‐Contaminated Bone Defects: Reconstruction with Multi‐Biofunctional GO/Cu‐Incorporated 3D Scaffolds
Authors: Yang Ying , Li Min , Zhou Bixia , Jiang Xulei , Zhang Dou , Luo Hang , Lei Shaorong 
Published: June 2022

AbstractLarge‐scale bone defects caused by traumatic injury or tumor resection, are accompanied by relatively high bacterial infection rates. Relevant clinical therapy encounters challenges of infection recurrence, poor vascularization, and bone destruction. Engineered substitutes endowed with multiple functions of bacterial eradication, osteoconductivity, and angiogenesis are urgently needed to address these challenges. Herein, graphene oxide/copper (GO/Cu) nanocomposite‐decorated polylactide‐co‐glycolide (PLGA)/β‐tricalcium phosphate (TCP) (P/T/GO/Cu) scaffolds are fabricated using 3D printing technology. A comprehensive evaluation of material characteristics and biological activities of these scaffolds is conducted and compared. This novel bone substitute has unique surface characteristics, and the incorporation of GO/Cu nanocomposites into the scaffolds exhibits improved antimicrobial and osteogenic potential and displays acceptable cytocompatibility. A subcutaneous implantation model in rats confirms the effective inhibition of abscess formation and inflammatory reactions, satisfactory neovascularization and tissue integration, and good biosafety of the implanted P/T/GO/Cu scaffolds. Eventually, a bacteria‐contaminated bone defect model is established in rabbits and significantly better new cancellous bone formation featuring collagen or osteoid deposition is clearly found in the defect regions implanted with P/T/GO/Cu scaffolds. Thus, this novel bone substitute with excellent bacterial inhibition, osteogenesis, and angiogenesis capabilities represents a promising strategy to satisfy the multiple demands for the repair of bacteria‐contaminated bone defects.
The organic premium of baby food based on market segments
Authors: Liu Yuting , Sam Abdoul G. 
Published: June 2022

AbstractParents may be more attentive to health and safety concerns when purchasing food for their babies due to the fragility of the digestive system of infants and their early stage of growth. The processing of organic baby food involves minimal use of toxic chemicals and synthetic food additives which may be attractive to health‐conscious parents. On the other hand, organic baby food is generally more expensive than nonorganic alternatives due to the cost of organic certification. The purpose of this paper is to estimate the price premium that parents are willing to pay for organic baby food and how it varies along several dimensions: organic label, food type based on developmental stage, retail channel, frequency of purchase of organic products, and over time. We apply the hedonic price model to Nielsen consumer panel data to isolate brand effects from the organic effects on product prices. The empirical results show that parents pay 17%–27% more, on average, for organic baby food than conventional alternatives, after controlling for a series of product and market characteristics. [EconLit Citations: D12, Q11, L66, C13].
A rare cause of infantile achalasia: GMPPA‐congenital disorder of glycosylation with two novel compound heterozygous variants
Authors: Geiculescu Irina , Dranove Jason , Cosper Graham , Edmondson Andrew C. , Morava‐Kozicz Eva , Carter Lauren B. 
Published: June 2022

AbstractAchalasia is rare in the pediatric population and should prompt clinicians to consider genetic disorders associated with this condition. While AAA syndrome (also known as Allgrove or Triple A syndrome) is commonly considered, GMPPA‐congenital disorder of glycosylation (CDG) should also be in the differential diagnosis. We report a 9‐month‐old female born to nonconsanguineous parents with achalasia and alacrima found to have two novel compound heterozygous variants in the GMPPA gene associated with GMPPA‐CDG. This rare disorder is commonly associated with developmental delay and intellectual disability. We discuss management of this disorder including the importance of confirming a genetic diagnosis and summarize reported cases.
Chromophore‐Inspired Design of Pyridinium‐Based Metal–Organic Polymers for Dual Photoredox Catalysis
Authors: Zhang Qingqing , Jin Yunhe , Ma Lin , Zhang Yongqiang , Meng Changgong , Duan Chunying 
Published: June 2022

Abstract2,4,6‐Triphenylpyrylium (TPT+) functions as a classic organic photocatalyst and exhibits a noteworthy absorption in the visible range, strongly oxidizing excited states, and a somewhat unstable structure. Inspired by the nuclear chromophore and dual catalysis strategy, herein, we report a universal photoredox platform constructed byTPT+‐mimic bridging ligands and reductive metal ions on the basis of metal–organic supramolecular systems for various organic couplings and molecular oxygen activation under visible‐light irradiation. Significant photoinduced electron transfer and ligand‐to‐metal charge‐transfer events are both integrated and regulated by the spatial and kinetic confinement effects of the structurally confined microenvironments, effectively improving the efficiency of electron transfer and radical–radical coupling processes in photocatalysis. This package deal provides a promising way for the design of novel photocatalysts and the development of versatile and sustainable synthetic chemistry.
Bis(imidazolium)‐1,3‐diphosphete‐diide: A Building Block for FeC2P2 Complexes and Clusters
Authors: Scharnhölz Moritz Theodor , Coburger Peter , Gravogl Lisa , Klose Daniel , Gamboa‐Carballo Juan José , Le Corre Grégoire , Bösken Jonas , Schweinzer Clara , Thöny Debora , Li Zhongshu , Meyer Karsten , Grützmacher Hansjörg 
Published: June 2022

AbstractReaction of the 6π‐electron aromatic four‐membered heterocycle (IPr)2C2P2 (1) (IPr=1,3‐bis(2,6‐diisopropylphenyl)‐1,3‐dihydro‐2H‐imidazol‐2‐ylidene) with [Fe2CO9] gives the neutral iron tricarbonyl complex [Fe(CO)3‐η3‐{(IPr)2C2P2}] (2). Oxidation with two equivalents of the ferrocenium salt, [Fe(Cp)2](BArF24), affords the dicationic tricarbonyl complex [Fe(CO)3‐η4‐{(IPr)2C2P2}](BArF24)2 (4). The one‐electron oxidation proceeds under concomitant loss of one CO ligand to give the paramagnetic dicarbonyl radical cation complex [Fe(CO)2‐η4‐{(IPr)2C2P2}](BArF24) (5). Reduction of 5 allows the preparation of the neutral dicarbonyl complex [Fe(CO)2‐η4‐{(IPr)2C2P2}] (6). An analysis by various spectroscopic techniques (57Fe Mössbauer, EPR) combined with DFT calculations gives insight into differences of the electronic structure within the members of this unique series of iron carbonyl complexes, which can be either described as electron precise or Wade–Mingos clusters.
Methylamine Lithium Borohydride as Electrolyte for All‐Solid‐State Batteries
Authors: Grinderslev Jakob B. , Skov Lasse N. , Andreasen Jacob G. , Ghorwal Shaiq , Skibsted Jørgen , Jensen Torben R. 
Published: June 2022

AbstractFast Li‐ion conductivity at room temperature is a major challenge for utilization of all‐solid‐state Li batteries. Metal borohydrides with neutral ligands are a new emerging class of solid‐state ionic conductors, and here we report the discovery of a new mono‐methylamine lithium borohydride with very fast Li+ conductivity at room temperature. LiBH4⋅CH3NH2 crystallizes in the monoclinic space group P21/c, forming a two‐dimensional unique layered structure. The layers are separated by hydrophobic −CH3 moieties, and contain large voids, allowing for fast Li‐ionic conduction in the interlayers, σ(Li+)=1.24×10−3 S cm−1 at room temperature. The electronic conductivity is negligible, and the electrochemical stability is ≈2.1 V vs Li. The first all‐solid‐state battery using a lithium borohydride with a neutral ligand as the electrolyte, Li‐metal as the anode and TiS2 as the cathode is demonstrated.
A validated liquid chromatography‐tandem mass spectroscopy method for the quantification of tolinapant in human plasma
Authors: Martins Vanessa , Wilsher Nicola , Lin Song , Oganesian Aram 
Published: June 2022

AbstractTolinapant (ASTX660), a pan‐selective inhibitor of apoptosis protein antagonist with dual cIAP/XIAP activity, was identified as a clinical candidate in preclinical efficacy, pharmacokinetic and safety studies. In order to assess tolinapant in first‐in‐human Phase I/II clinical trials, a validated bioanalytical method was required to determine plasma pharmacokinetics. Tolinapant and d4‐tolinapant were extracted from human plasma using liquid‐liquid extraction. Separation chromatography was performed on a Acquity BEH C18 1.7 µM, 50 mm × 2.1 mm i.d. column, using a mobile phase of 0.1% formic acid in water and 0.1% formic acid in acetonitrile. Mass spectrometry detection was performed by positive turbo ion spray ionisation, in multiple reaction monitoring mode. The method was validated according to the US Food and Drug Administration (FDA) guidelines. The method has a quantifiable linear range of 1–500 ng/mL (r2 = 0.999). The intra‐ and inter‐day coefficients of variation were < 11.4%. Dilution QC samples agreed with prepared concentrations, with a precision of 1.5% and accuracy of 101%. Tolinapant mean recoveries ranged from 85.1–94.4 % with negligible matrix effects. A highly sensitive and selective LC‐MS/MS bioanalytical method was developed and validated. The method was successfully applied in Phase 1/2 clinical trials to determine the human pharmacokinetic profile of tolinapant.
Back to the future: Fatty acids, the green genie to design smart soft materials
Authors: Fameau Anne‐Laure , Marangoni Alejandro G. 
Published: June 2022

AbstractFatty acids are widely used in industries for various applications as soaps or in their crystalline form. Fatty acid soaps are used as surface‐active agent to stabilize foams and emulsions, for detergency, and surface wetting. Fatty acid molecules in organic solvents are used as low‐molecular‐mass organic gelators. Currently, there is a renewed interest in using fatty acids in industrial applications instead of petrochemical surfactants since fatty acid soaps are green surfactants. Fatty acids exhibit also many advantages, including the design of responsive soft‐materials. Fatty acid soaps are natural pH and thermoresponsive surfactants, which can lead to responsive foams and emulsions. In their crystalline form, fatty acid crystals in both aqueous and non‐aqueous solvents stabilize liquid foams. These crystals are also efficient in the production of liquid marbles. Fatty acids are solvosurfactants with the ability to form microemulsions and capillary suspensions. In this review, we illustrate how fatty acid molecules can be used in the manufacture of multiresponsive soft‐materials ranging from aqueous and non‐aqueous foams, emulsions, nanoemulsions, microemulsions, liquid marbles and capillary suspensions.
UV curing: An alternative method for fixation of β‐carotene containing microparticles substances onto cotton fabrics by acrylic binder
Authors: Pektaş Koray , Sarıışık Merih , Erkan Gökhan , Ziylan Aylin 
Published: June 2022

AbstractCapsulation technology is one of the methods that have been utilized for gaining various functional properties of textile materials. With the technology, in recent years, textile materials have been made to exhibit functions such as vitamins, fragrances, moistening effect, insect repellent, and anti‐cellulite. To establish permanent bonding between capsule‐based materials and textile materials, which also provides efficiency against washing, crosslinking agents are used. Commercial capsules are applied to a fabric by using acrylics or polyurethanes as the cross‐linker at a drying temperature of around 100°C and thermo‐fixation conditions are between 110 and 130°C. The capsules used for fragrance and aromatherapy applications, which contain volatile oil, can be affected in high‐temp conditions that cause evaporation and degradation of active ingredient. In this study, beta‐carotene as the active ingredient was dispersed within ethyl cellulose via spray drying first and then applied to textile materials to maintain the tanning effect. Besides thermal curing, the UV curing process with different photoinitiators will be utilized for the fixation of capsules onto textile materials. Hence, the UV curing technique will be used as an alternative to the thermal fixing of conventional cross‐linkers. After application of the capsules onto textile materials, characterization, and various efficiency tests such as color measurement, X‐ray diffraction, thermogravimetric analysis were performed. As a result, textiles containing β‐carotene microparticles that are resistant to 10 washing cycles were produced. Moreover, all the β‐carotene fixed fabric showed antioxidant activity and thermal stability. Consequently, it could be said that the UV curing process on textile materials can be an alternative curing process to the thermal curing process.
The effects of skull flattening on suchian jaw muscle evolution
Authors: Sellers Kaleb C. , Nieto Mauro Nicolas , Degrange Federico J. , Pol Diego , Clark James M. , Middleton Kevin M. , Holliday Casey M. 
Published: June 2022

AbstractJaw muscles are key features of the vertebrate feeding apparatus. The jaw musculature is housed in the skull whose morphology reflects a compromise between multiple functions, including feeding, housing sensory structures, and defense, and the skull constrains jaw muscle geometry. Thus, jaw muscle anatomy may be suboptimally oriented for the production of bite force. Crocodylians are a group of vertebrates that generate the highest bite forces ever measured with a flat skull suited to their aquatic ambush predatory style. However, basal members of the crocodylian line (e.g., Prestosuchus) were terrestrial predators with plesiomorphically tall skulls, and thus the origin of modern crocodylians involved a substantial reorganization of the feeding apparatus and its jaw muscles. Here, we reconstruct jaw muscles across a phylogenetic range of crocodylians and fossil suchians to investigate the impact of skull flattening on muscle anatomy. We used imaging data to create 3D models of extant and fossil suchians that demonstrate the evolution of the crocodylian skull, using osteological correlates to reconstruct muscle attachment sites. We found that jaw muscle anatomy in early fossil suchians reflected the ancestral archosaur condition but experienced progressive shifts in the lineage leading to Metasuchia. In early fossil suchians, musculus adductor mandibulae posterior and musculus pterygoideus (mPT) were of comparable size, but by Metasuchia, the jaw musculature is dominated by mPT. As predicted, we found that taxa with flatter skulls have less efficient muscle orientations for the production of high bite force. This study highlights the diversity and evolution of jaw muscles in one of the great transformations in vertebrate evolution.
History of nasopharyngeal study: A 5,000‐year odyssey into our evolving understanding of a small but vital region
Authors: Pagano Anthony Santino , Márquez Samuel 
Published: June 2022

AbstractThe nasopharynx has been understudied relative to neighboring anatomical regions. It is a highly complex, integrated space whose function, development, and evolution remains unclear after nearly 5,000 years of study. Historically, most work on the nasopharynx was done with a focus on adjacent structures. It has most often been mentioned in relation to the middle ear (via the Eustachian tube) in ancient texts and has only later been given a designation as one of three portions of a tripartite pharynx among adult humans. As human dissection became practiced more widely in Renaissance Europe, understanding of the nasopharyngeal boundaries improved. With further advancements in the study of nasopharyngeal development, evolution, and anatomical variation from the 19th century up until the present, this region has been shown to be functionally vital and still complicated to define.
Disciplinary contributions to research topics and methodology in Library and Information Science—Leading to fragmentation?
Authors: Vakkari Pertti , Chang Yu‐Wei , Järvelin Kalervo 
Published: June 2022

AbstractThe study analyses contributions to Library and Information Science (LIS) by researchers representing various disciplines. How are such contributions associated with the choice of research topics and methodology? The study employs a quantitative content analysis of articles published in 31 scholarly LIS journals in 2015. Each article is seen as a contribution to LIS by the authors' disciplines, which are inferred from their affiliations. The unit of analysis is the article‐discipline pair. Of the contribution instances, the share of LIS is one third. Computer Science contributes one fifth and Business and Economics one sixth. The latter disciplines dominate the contributions in information retrieval, information seeking, and scientific communication indicating strong influences in LIS. Correspondence analysis reveals three clusters of research, one focusing on traditional LIS with contributions from LIS and Humanities and survey‐type research; another on information retrieval with contributions from Computer Science and experimental research; and the third on scientific communication with contributions from Natural Sciences and Medicine and citation analytic research. The strong differentiation of scholarly contributions in LIS hints to the fragmentation of LIS as a discipline.
Advances in early diagnosis of cervical cancer based on biosensors
Authors: Ghaleh Hadi Esmaeili Gouvarchin , Shahriary Alireza , Izadi Morteza , Farzanehpour Mahdieh 
Published: June 2022

AbstractHuman papillomavirus (HPV) is a causative agent of cervical cancer among women worldwide. Serological and molecular tests are commonly used to detect and identify HPV, but all the detection methods for HPV have some limitations. Nowadays, considerable advancements in nanosensors have enabled monitoring of hybridization procedures dynamically for HPV detection. Biosensors, as effective, quick, economical, and highly sensitive tools, can be used in the diagnosis of HPV as an alternative technique instead of other detection methods. Biosensor detection methods of HPV in use from 2000 to 2021 were investigated using several databases such as Google Scholar, Scopus, PubMed, and the Scientific Information Database. Furthermore, a manual search of the references of the retrieved articles was performed. On analyzing the most recently developed biosensors for HPV identification, we observed that three biosensor systems, electrochemical, optical, and piezoelectric systems, are the main transducers used in the development of HPV biosensors. The aim of this review is to examine recent research on biosensors for the detection of HPV and perform a comparison with other diagnostic methods. Considering the importance of rapid HPV detection in the control of infection and development of public health measures, improvement of biosensors as an economical and quick method can be very useful in the diagnosis of HPV.