bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between occurrence of acute stroke and job strain
Authors: Vahdati Samad Shams , Ala Alireza , Hosseinzadeh Naeimeh , Asenjan Maryam Rahimpour , Gorashian Gisou , Sarmadian Amirreza Jabbaripour 
Published: April 2022

Abstract
Background
Stroke is a type of circulation dysfunction in some areas of the brain that causes neurologic events. Stroke is one of the main causes of morbidity, mortality and disability around the world which has various risk. Psychosocial stress can be known as a risk factor for stroke.
Objectives
Due to the considerable prevalence of stroke in our country and the lack of studies related to stroke and occupational stress in our area, in this study we aimed to find out the relation between job strain and stroke, as well as the two types of strokes.
Methods
The present study was designed and conducted as an observational and analytical study. This study included patients who self-referred to the emergency department with neurologic defects from 1 January 2019 to 1 July 2019 and were admitted as stroke patients. Demographic data of patients, determined by interview and the type of stroke diagnosed by imaging, were recorded and collected by the researcher through a researcher-made checklist.
Results
In this study, 301 participants were enrolled. Patients' mean age was 66.93 ± 15.41 years. 49.2% of these patients were male and 50.8% were female. 1.7% of them had night shift jobs and 7% had high job. In our study housewives (46.8%), employees (10.6%), farmers (7.9%) and self-employments (7.3%) were suffering stoke more frequently. 91% had an ischemic stroke and 9% had hemorrhagic stroke.
Conclusions
Based on statistical analysis and mathematical data no significant relation was found between job types, job difficulties, night shifts, and stroke.
The Indian real estate regulations and urban homebuyers: impact assessment
Authors: Chawla Neelam , Kumar Basanta 
Published: April 2022

Abstract
The previously unregulated urban housing and real estate market scenario began to change by promulgating a new law, i.e., the Indian Real Estate (Regulation and Development) Act, 2016 (RERDA, 2016/Act). Claims are that the Act has been saving homebuyers from exploitation by the promoters' evasive and aggressive approach and impacting the economy and society. The paper briefly examines relevant provisions of the Act and judicial pronouncements protecting urban homebuyers' interests; it analyzes in-depth their impact on them in particular and society by empirically studying 540 sample homebuyers' reactions. Besides, the study discusses the implications of regulating foreign direct investments in aiding current policy perceptions supporting housing vis-a-vis the economy. The results show that very often, builders exploit the homebuyers. Timely judiciary interventions have removed the initial bottleneck created by builders, positively impacting builders' and governments' safeguarding of homebuyers' interests. Even four years after the Act's implementation, its implementation remains uneven.
Hsa-circ-0064636 regulation of the target gene VDAC1/UBE4A by hsa-miR-326/hsa-miR-503-5 in osteosarcoma
Authors: Cheng Jianwen , Yan Guohua , Huang Hanji , Qin Yongnian , Li Kanglu , Zheng Mingjun , Mo Lichuan , Zheng Junjian , Jiang Rui , Huang Nanchang , Wei Renjie 
Published: April 2022

Abstract
Background: Circular RNAs (circRNAs) are a subclass of non-coding RNAs that play a critical role in regulating gene expression in eukaryotic organisms. Recent studies have revealed the critical role of circRNAs in cancer progression. However, there are few studies on the function of hsa-circ-0064636 in osteosarcoma (OS).Methods: The differential expression of hsa-circ-0064636 in OS cell lines was detected by [1] quantitative real-time PCR (qRT-PCR). Differentially expressed mRNAs and miRNAs were screened in OS mRNA and miRNA expression datasets. MiRNAs that interacted with hsa-circ-0064636 were predicted by RNAhybrid, TargetScan and miRanda, and were further detected using RNAhybrid, TargetScan and miRanda. MiRWalk, miRMap, and miRNAMap were used to perform target gene prediction on the intersected miRNAs to construct a circ-miRNA-mRNA interactor network. The target genes were then subjected to survival analysis using PROGgeneV2, and then a circ-miRNA-mRNA interaction subnetwork was formed, and the prognostic impact of target genes was revealed.[2] Results: The qRT-PCR experiments showed that hsa-circ-0064636 was significantly overexpressed in the OS cell lines. Hsa-mir-326(miR-326) and hsa-mir-503-5p(miR-503-5p) are targeting miRNAs of hsa-circ-0064636 in the target genes obtained from the miR-326 and miR-503-5p screens. UBE4A and VDAC1 have a significant effect on prognosis. UBE4A is a target gene of miR-326, while VDAC1 is a target gene of miR-503-5p.Conclusion: Hsa-circ-0064636 may be involved in OS development by inhibiting the expression of miR-326 and miR-503-5p, thus regulating that of VDAC1 and UBE4A.
Effect of a Daily Collagen Peptide Supplement on Digestive Symptoms in Healthy Women: 2-Phase Mixed Methods Study
Authors: Abrahams Mariette , O’Grady Rochez , Prawitt Janne 
Published: April 2022

Background
The effect of dietary collagen on managing digestive symptoms is currently lacking in the literature.

Objective
To gain a better understanding of this issue, we conducted a 2-phase mixed methods study.

Methods
Phase 1 was a mixed methods design to explore current attitude and practice among consumers and health care practitioners. The findings were used to design an 8-week phase 2 digital study called Gutme! conducted in the United States in healthy female volunteers (BMI>25 kg/m2). Our aim was, first, to determine the feasibility of conducting a fully digital mixed methods study; second, the study explored the effect of an 8-week daily supplementation of 20 g dietary collagen peptide (Peptan) on digestive symptoms. Phase 2 was a prospective, open-label, longitudinal, single-arm study. Participation involved 2 weeks of baseline tracking (digestive symptoms, mood, stool, and lifestyle) using an app, followed by 8 weeks of tracking and taking 20 g collagen peptide supplement split into 2 dosages per day. Participants were required to complete a web-based symptom questionnaire at baseline, week 2, and week 8, as well as participate in 2 scheduled video interviews.

Results
Phase 1 revealed that consumer awareness of collagen for digestive health is low (64/204, 31.4%). Among the dietitians prescribing collagen for their patients, the most common dosage was 20 g a day with notable effects after 6 weeks of intake. Within the phase 2 study, of the 40 recruited participants, 14 (35%) completed the full course of supplementation. The findings indicate that 93% (13/14) of those who completed the study experienced a reduction in digestive symptoms, which included bloating.

Conclusions
A mixed methods digital study design is feasible and acceptable for collecting relevant data in a real-life setting. The use of a 20 g daily collagen peptide supplement may reduce bloating and improve mild digestive symptoms in otherwise healthy female adults in the absence of any other dietary or lifestyle interventions.

Trial Registration
ClinicalTrials.gov NCT04245254; https://clinicaltrials.gov/ct2/show/NCT04245254
Strategi Transformasi Sosial Komunitas Prenjak Tapak dalam Penguatan Ecological Citizenship Terhadap Ketahanan Lingkungan Daerah Kota Semarang
Authors: Mardiyah Shoim , Wahidin Darto , Kaelan Kaelan , Armawi Armaidy 
Published: April 2022

ABSTRAK Ecological citizenship sebagai bentuk pemahaman dan implementasi keterlibatan warga negara dalam menjaga lingkungan hidupnya tidak akan terwujud tanpa adanya transformasi sosial yang mengawali. Penguatan ecological citizenship sejatinya sangat diperlukan demi mendukung terwujudnya suatu ketahanan lingkungan daerah. Penelitian ini dilakukan di Dusun Tapak, Kelurahan Tugurejo, Kecamatan Tugu, Kota Semarang, Provinsi Jawa Tengah. Pendekatan yang digunakan yakni kualitatif dengan bentuk data yang bersifat deskriptif. Informan ditentukan secara purposive sampling yang dipilih dengan pertimbangan dan tujuan tertentu. Teknik pengumpulan data yang digunakan dalam penelitian ini yaitu observasi, wawancara mendalam, focus group discussion (FGD), dan dokumentasi.Hasil penelitian ini menunjukkan bahwa adanya strategi yang dilakukan Komunitas Prenjak Tapak untuk mentransformasi masyarakat sekitar. Transformasi yang terjadi selama ini berbentuk transformasi lingkungan dan transformasi mindset masyarakatnya. Saat ini Komunitas Prenjak Tapak tengah menghadapi para investor yang akan menanamkan investasinya di lahan sekitar area konservasi mangrove. Adapun kepedulian Pemerintah Daerah Kota Semarang saat ini lebih memihak kepada para investor. Padahal mangrove sangat dibutuhkan untuk memperkuat ketahanan lingkungan Kota Semarang yang telah dikenal dengan banjir robnya setiap tahunnya
Theory of Planned Behavior in predicting condom use in Latin-American Women
Authors: Enríquez-Negrete David Javier , Sánchez-Medina Ricardo , Bárcena-Gaona Susana Xóchitl , Chávez-Santos Itzel Guadalupe 
Published: April 2022

Background: The theory of Planned Behavior (TPB) is used to predict condom use. The present study assessed the causal relationships of the TPB in a cultural context different from the one that was proposed. Objective: To assess the causal relationships among the variables proposed by the TCP to determine if they predict consistent condom use in two groups of Latina women and to identify the inter-group similarities in both groups and the discrepancies with what the model proposes for the North American population. Method: A set of variables were evaluated in two samples of Latina women (Mexican and Argentine): consistency of condom use, intention to use condoms in the next sexual encounter, the subjective norm of friends and parents, attitudes towards condoms, and perceived behavioral control to use condoms. We used the Linear regression analysis. Results: Intention to use condoms was found to be the best predictor of condom use. Subjective norm was more important than attitudes; although the latter variable was not configured as a predictor in Argentine women. Conclusion: The associations between the CTP variables and the predictive values of the variables may change according to the cultural group evaluated; perceived behavioral control, in both samples, was not a direct predictor of condom use behavior, but it was a predictor of intention to use condoms. In addition, we discussed the relevance of the variables proposed by the TCP about the cultural context of Latinos and the critical use of the model in populations other than North America.
Diagnostic values of serum IL-17A and IL-18 in Rheumatoid arthritis and Correlation with treatment
Authors: Yousif Noorhan H. , Ibraheem Shaima R. , Mahmood Aseel shakir 
Published: April 2022

Background: Rheumatoid arthritis (RA) is an autoimmune disorder that involves autoantibodies attacking and weakening joints. RA is characterized by leukocyte (Monocyte, Lymphocyte mast cell .etc) infiltrations into the synovial compartment leading to inflammation in the synovial membrane. Synovitis leads to the release of pro-inflammatory cytokines, matrix metalloproteinases, chemokines, complement proteins, and growth factors.
Objective: The current study pointed to verify the diagnostic values of interleukin -17 A and interleukin -18 in Rheumatoid arthritis (RA) patients and the effect of treatment thereon.
Study subjects and methods: A total of 88 samples with RA were selected from the health clinics of AL-Yarmouk teaching hospital/rheumatology clinic in Baghdad, with female rheumatoid arthritis patients as the patient group (50) and (38) healthy females as the control group. All patients were exposed to clinical, laboratory, and ultrasound assessments, besides measuring the serum level of both (IL-17A and IL-18) by the method of Enzyme-linked immunosorbent assay (ELISA).
Results: The results show that there is a significant difference (p≤0.05) in IL-17A levels between patients and controls. The concentration of IL-17A in premenopausal patients is higher when compared to control groups (18.06 ± 3.85 vs 15.71 ± 1.82 pg/ml), so, the concentration in postmenopausal studied groups (17.19 ± 2.91 vs 14.13 ± 1.06 pg/ml).
Also, there are significant differences (p≤0.05) in the level of IL-18 between the patients and the control; it is found that the level of IL-18 within the premenopausal patients was higher compared to the control (16.09 ± 9.69 vs 12.52 ± 8.30 pg/ml).
Conclusion: A High level of IL-17A in RA patients contributes to the pathogenesis of RA as an inflammatory disease. As well as, the elevated levels of IL-18 suggest its physiological role to induce inflammatory disorder Treatment with (MTX and Etanercept) causes a decrease in the inflammatory markers of this disease RF in patient groups.
Water quality assessment in the region of Vale dos Sinos trough the alternative model Caenorhabditis elegans
Authors: Oliveira Talitha Stella Sant’Ana , Bigolin Cassiana , Silva Laura Cé da , Menezes Júlia Machado , Ayres Tainara Amanda , Rodrigues Gabriela Zimmermann Prado , Rodrigues Vinícius Bley , Muller Isadora Ritter , Gehlen Günther , Betti Andresa Heemann , Charão Mariele Feiffer 
Published: April 2022

The determination of the condition of river water quality is critical to establishing sustainable water resource management policies. The use of bioindicators tests for the evaluation of water quality is a valuable tool, and the nematode C. elegans is described as a good organism to assess toxicological risks in aquatic and soil environments. The samples of water were collected in three stretches of the Paranhana and Ilha rivers (P1, P2 and P3) in November (spring) of 2018, January (summer) of 2019, April (autumn) of 2019, and August (winter) of 2019. The physic-chemical parameters were analyzed according to the standard methods (Standard Methods for the examination of Water and Wastewater 23rd edition). The nematode strains used are savage lineage N2 and were obtained through the Caenorhabidits Genetics Center (CGC) for the bioindicator test. The development evaluation was verified by the body surface area measurement of 20 nematodes which were quantified thru the ImageJ software. Most of the physic-chemical parameters were within the limits recommended by CONAMA, but aluminum, that presented values ten times higher than the recommended limit. Significant differences were observed in the nematodes development from all the samples when compared to the control group (p<0,001). The analysis of nematode development demonstrated that the bioindicator was sensitive to the research, showing that ecotoxicological assays are important for a more realistic scenario of threats to water quality, and C. elegans allows this assessment to be performed adequately.
Research of neural network for weld penetration control
Authors: Ding Dukun 
Published: April 2022

Abstract
A method has been proposed for welding penetration status prediction in the paper. First, an experimental system was set up and welding experiments were performed. Some groups of welding images could been obtained. A composite filtering system composed of a neutral light reduction filter and a narrow band filter was developed to filter the weld arc disturbance. Some operations were performed to the images, namely the median filter and gray transformation. Then a neural network was setup, containing three layers. The inner widths of pool xn
, the outer widths of pool xw
, the width difference values e between the inner and outer of pool, ratios of inner pool widths Rn
and ratios of outer pool widths Rw
between two adjacent images were determined to be the input parameters. The penetration parameter p was chosen to be the output. Based on the images, groups of pool parameter data have been obtained and used to train the network. In this way, the weld penetration prediction model can be deduced. Finally, verification tests have been done. It showed that weld penetration situation predicted by the model is fit to its real condition. The accuracy rate is up to 96%, which affords a new way for penetration detection.
Retrieval of Vertical Structure of Raindrop Size Distribution from Equatorial Atmosphere Radar and Boundary Layer Radar
Authors: Vonnisa Mutya , Shimomai Toyoshi , Hashiguchi Hiroyuki , Marzuki Marzuki 
Published: April 2022

This work develops an algorithm to retrieve the vertical structure of the raindrop size distribution (DSD) of rain from simultaneous observations of 47 MHz Equatorial Atmosphere Radar (EAR) and 1.3 GHz Boundary Layer Radar (BLR) at Koto Tabang, West Sumatra, Indonesia (0.20°S, 100.32°E, 865 m above sea level). EAR is sensitive to the detection of turbulence, and BLR is susceptible to identifying precipitation echo. The EAR Doppler spectrum broadening effects due to turbulence and finite radar beam width were reduced using the convolution process. The Gaussian function was used to model the turbulence Doppler spectrum. A non-linear least-squares fitting method was applied to retrieve DSD parameters. Subsequently, the equations to estimate DSD using this dual-frequency algorithm assume the gamma DSD model to retrieve the distribution from the Doppler spectrum of precipitation echo. The precipitation events on April 23, 2004 on the Coupling Processes in the Equatorial Atmosphere (CPEA-I) project have been analyzed. Results show that the precipitation spectrum obtained using the dual-frequency method is higher, more precise, and well-fitted than the single-frequency method, meaning the dual-frequency method has great potential to be used in observing the microphysical process and remote sensing application analysis of DSD in Indonesia, particularly at Koto Tabang. The analyses show various microphysical processes that occur in the rain, such as coalescence, evaporation, break-up, and condensation. Furthermore, for the purpose of easier remote sensing application analysis of profile DSD characteristics, we use a DSD ΔΖMP parameter. ΔΖMP is a rain rate insensitive DSD parameter representing mean drop size. The trend of ΔZMP is not totally uniform with regards to rain rate and reflectivity factors, with ΔZMP higher in the first half of the event and becoming lower toward the end. This suggests that we have to use different Z-R relations within the event. Doi: 10.28991/ESJ-2022-06-03-02 Full Text: PDF
Análisis de satisfacción e impacto social y ambiental de los programas de servicio comunitario de la Universidad Técnica de Cotopaxi
Authors: Ortiz Bustamante Vladimir Marconi , Mantilla Parra Carlos Washington , Moreano Martínez Luis David , Salgado Molina Graciela Noemi 
Published: April 2022

Los diferentes programas de vinculación con la sociedad buscan responder a las expectativas y necesidades de la sociedad, generando la satisfacción e impacto positivo en los sectores de intervención, por ello el presente estudio analiza la satisfacción e impacto de los programas de la Universidad Técnica de Cotopaxi, determinándose de esta manera el beneficio que estos generaron y de ser necesario su continuidad o replica en programas como Educomunicación Intercultural, Sostenibilidad administrativa y financiera, de las organizaciones de economía popular y solidaria y de la MPYMES de la provincia de Cotopaxi, Energía y Tecnología al servicio de la Sociedad, Desarrollo de mi tierra, UTC Junto al Pueblo, Programa de Vinculación Centro de emprendimiento. Por lo expuesto, el presente estudio propone un modelo para la evaluación de impacto social y ambiental de los programas de vinculación con la sociedad.
Percepción de los estudiantes universitarios sobre el proceso de enseñanza aprendizaje en la virtualidad
Authors: León Monar Patricia De Lourdes , Quizhpe Baculima Víctor Hugo , Borja Borja Carmita Galudth , Alarcón Quinatoa Gina Jaqueline 
Published: April 2022

El presente trabajo investigativo se ha desarrollado para conocer la percepción de los estudiantes universitarios sobre el proceso de enseñanza aprendizaje en la virtualidad en la Carrera de Mercadotecnia de la Universidad Estatal de Bolívar. La investigación tiene un alcance descriptivo, con un enfoque cuali–cuantitativo. Los hallazgos más significativos son: El 58,3% de los encuestados volverían voluntariamente a clases presenciales, siendo en general la principal preocupación con el 46,8% el temor a contagiarse de Covid19 y sus variantes; sin embargo, la mayoría de encuestados equivalentes al 42,5% prefiere continuar con clases en línea principalmente por prevenir contagios, estudiar y trabajar a la vez y por condiciones económicas. En cuanto a la experiencia de las clases virtuales manifiestan: el 57,5% que la universidad se ha adaptado adecuadamente a la virtualidad; mientras el 55,1% está de acuerdo que las clases en línea mantienen el nivel de calidad que recibían en la presencialidad; el 44,1% califica como buena la metodología de enseñanza aprendizaje empleada por los docentes; el 69,8% concuerdan que el aprendizaje ha sido significativo en la modalidad en línea o virtual, sin embargo, el 75,4% refiere como principal dificultad la conectividad a internet; el 69,3% considera que tendrá déficit en su formación y aprendizaje actual en comparación con promociones anteriores de la carrera, pero, el 59,8% aprecia que su calificación promedio a tenido un impacto positivo. Por otro lado, en cuanto a la satisfacción de los estudiantes, la mayoría de encuestados concuerdan favorablemente que la modalidad virtual le ha permitido desarrollar sus destrezas y habilidades intelectuales, cubriendo sus expectativas de la carrera, manteniendo la calidad de la educación y su rendimiento académico, además, perciben que se han incrementado las oportunidades laborales para los profesionales en Marketing o Mercadotecnia a raíz de la pandemia. Finalmente, las conclusiones más relevantes son: El proceso de enseñanza aprendizaje en la línea o virtual ha sido significativo para el estudiantado, donde las Instituciones de Educación Superior deben responder a los nuevos requerimientos bajo la disposiciones y normativas vigente, involucrando el valioso accionar docente para generar experiencias redituables y relevantes con los estudiantes.
Fatiga por compasión en personal sanitario de un servicio oncológico
Authors: Idrovo Regalado Eugenio Xavier , Martínez Suárez Pedro 
Published: April 2022

La fatiga por compasión es una manera equivoca de afrontar el estrés crónico, la cual es provocada por un desgaste emocional debido a la constante atención a personas que sufren un malestar ya sea médico o psicológico. De esta manera, la presente investigación busca describir las apreciaciones que tiene el personal de la salud en relación a la fatiga por compasión. Este estudio tuvo un diseño cualitativo, de tipo descriptivo y con una cohorte transversal, en donde mediante un “Focus Group”, se realizó una entrevista grupal destinada a diversos profesionales de la salud que tienen una relación directa con el tema. Entre los participantes tuvimos un médico gastroenterólogo, el cual mostro la relación que se tiene entre los estados de ánimo y los estados fisiológicos; una psicóloga general, la cual describió los efectos que pueden generar estrés en los individuos; un psicólogo organizacional, quien mostro los efectos entre el aspecto laboral y personal y una enfermera que trabaja con pacientes con cáncer, la cual indicaba la relación paciente-personal sanitario. En este sentido fatiga por compasión es un tipo de estrés que afecta de forma principal a los trabajadores de la salud, pero también se encuentran afectados otro tipo de personal como es el administrativo, psicólogos o aquel relacionado con situaciones de riesgo. Sus consecuencias son similares a las del estrés post traumático y se diferencia del burnout debido a que las personas que lo padecen tienen alta empatía con los pacientes y una alta realización personal.