bluuebunny/crossref_metadata_2025_split huggingface dataset:
CAD/CAM single‐retainer monolithic zirconia ceramic resin‐bonded fixed partial dentures bonded with two different resin cements: Up to 40 months clinical results of a randomized‐controlled pilot study
Authors: Bilir Halenur , Yuzbasioglu Emir , Sayar Gulsilay , Kilinc Delal Dara , Bag Harika Gozde Gozukara , Özcan Mutlu 
Published: August 2022

AbstractPurposeThis pilot study was part of a larger study planned for the future which aimed to compare the clinical success of two different resin cements used in the cementation of CAD/CAM single‐retainer monolithic zirconia ceramic resin‐bonded fixed dentures (RBFPDs).MethodsTwenty‐four RBFPDs were fabricated with monolithic zirconia (Katana™ Zirconia HT, Kuraray Noritake Dental Inc, Tokyo, Japan). Panavia F2.0 (PF2.0; n = 12) and Panavia V5 (PV5; n = 12) were used for cementation. The survival period was defined as the time when the restoration was placed in the mouth and lasted until an irreparable damage occurred. The repairable failures were identified as relative and irreparable failures were identified as absolute failure. The survival rate of the RBFPDs was determined by the Kaplan–Meier estimator. Statistical significance was set at p < 0.05.ResultsThe mean observation times of the PF2.0 group and the PV5 group were 40.45 ± 6.15 months and 40.18 ± 6.41 months, respectively. Four failures occurred in the PF2.0 group. No failure was observed in the PV5 group. The curves of survival rate (PF2.0 = 80%, PV5 = 100%) showed no statistically significant difference (p = 0.031), although success rate (PF2.0 = 66.7%, PV5 = 100%) showed statistically significant difference (p = 0.317).ConclusionUp to 40 months mean follow‐up period, performance of RBFPDs bonded with PV5 was better than with PF2.0.Clinical SignificanceFor clinicians, it is a matter of hesitation to apply single‐retainer RBFPDs. This study contains results of 40 months (minimum 32, maximum 50.47 months) clinical follow‐ups of single‐retainer RBFPDs. These results will enlighten clinicians about the clinical success of the resin cement type for single‐retainer monolithic zirconia ceramic RBFPDs.
Detection of trh+Vibrio parahaemolyticus in seafood by lac dye coloration‐based label‐free lateral flow immunoassay strip
Authors: Liu Tao , Wu Meijiao , Tian Yachen , Liu Xiaoting , Liu Cheng , Xu Qingqiang , Liu Qing 
Published: August 2022

AbstractVibrio parahaemolyticus (V. parahaemolyticus) is an important foodborne pathogen known to cause severe enteric disease. Thus, timely detection of V. parahaemolyticus in seafood is crucial to prevent food poisoning and reduce economic losses. Traditional lateral flow immunoassay strips (LFIS) required good labelling materials and pairing of two antibodies, which made them costly and difficult to manufacture. In this study, a label‐free and lac dye coloration‐based LFIS (LD‐LFIS) to detect trh+ V. parahaemolyticus was developed for the first time. Lac dye was used to stain V. parahaemolyticus, and LFIS was used to detect stained bacteria. Dimethyl sulphoxide (DMSO) and simultaneous mordanting were chosen as the best solvent and the best staining method for lac dye. In addition, three mordants [KAl(SO4)2·12H2O, NH4Fe(SO4)2·12H2O, and AlCl3·6H2O] were selected to improve dyeing efficiency. The detection limit of LD‐LFIS was 3.9 × 105 CFU/ml when NH4Fe(SO4)2·12H2O was used as mordant. Feasibility of the LD‐LFIS method was verified by detecting trh+ V. parahaemolyticus in true and spiked seafood samples. The method developed in this study is expected to reduce restrictions on labelling materials and pairing of two antibodies on LFIS, and proposes a novel idea for the rapid detection of V. parahaemolyticus in seafood.
Residential substance use treatment outcomes for pregnant and postpartum women: Distinct patterns for women enrolled before versus during the COVID‐19 pandemic
Authors: Chou Jessica L. , Noel Jeffrey G. , Williams Catherine , Spruell Sharon , Nixon Kevana , Riedel Edward , Zaarur Asif 
Published: August 2022

AbstractIntroductionSubstance use among pregnant and postpartum women (PPW) is a serious public health concern. The COVID‐19 pandemic has exacerbated substance use among the general population including pregnant women, and disrupted operations for substance use treatment centers. Little is known about the outcomes of substance use treatment for PPW before and during the COVID‐19 pandemic.MethodData from a longitudinal program evaluation were analyzed to examine outcomes among 136 PPW participating in a residential SUD treatment program, and to explore differences in treatment outcomes for women who enrolled in services before versus during the COVID‐19 pandemic. Analyses were used to test the significance of change from treatment intake to 6‐month post‐intake on assessments of substance use, mental health symptoms, and functioning collected to evaluate the Healthy Families Program (HFP), a comprehensive program for PPW located within a gender‐specific SUD treatment facility in the United States.ResultsResults indicated that from treatment intake to follow‐up assessment, clients self‐reported statistically significant improvements in family functioning and daily functioning as well as reduced days of substance use. Notably, the rate of treatment intakes declined during the COVID‐19 pandemic. In separate analyses by subgroup, mental health indicators showed improvements only for clients engaged in treatment before the COVID‐19 pandemic and not for clients served during the COVID‐19 pandemic, but substance use decreased significantly for both pre‐pandemic and pandemic enrollees.ConclusionSpecialized treatment considerations and implications for PPW are discussed, including a need for added emphasis on co‐occurring mental health symptoms and family system stress during a pandemic, and the role of nurses in identifying and addressing these concerns. Additionally, potential relapse prevention efforts during COVID‐19 for PPW with substance use disorders are examined.Clinical RelevanceThe present research continues to highlight the importance of specialized treatment programming for PPW with SUDs as well as the potential need for additional recovery support mechanisms to be utilized during the COVID‐19 pandemic.
Ontogeny of the paraphalanges and derived phalanges of Hemidactylus turcicus (Squamata: Gekkonidae)
Authors: Griffing Aaron H. , Gamble Tony , Bauer Aaron M. , Russell Anthony P. 
Published: August 2022

AbstractGekkotan lizards of the genus Hemidactylus exhibit derived digital morphologies. These include heavily reduced antepenultimate phalanges of digits III and IV of the manus and digits III–V of the pes, as well as enigmatic cartilaginous structures called paraphalanges. Despite this well‐known morphological derivation, no studies have investigated the development of these structures. We aimed to determine if heterochrony underlies the derived antepenultimate phalanges of Hemidactylus. Furthermore, we aimed to determine if convergently evolved paraphalanges exhibit similar or divergent developmental patterns. Herein we describe embryonic skeletal development in the hands and feet of four gekkonid species, exhibiting a range of digital morphologies. We determined that the derived antepenultimate phalanges of Hemidactylus are the products of paedomorphosis. Furthermore, we found divergent developmental patterns between convergently evolved paraphalanges.
Association between sleep quality, hypertensive disorders of pregnancy, and sleep‐disordered breathing in pregnant women with and without obesity: An observational cross‐sectional study
Authors: Ura Midori , Fujimoto Keisaku , Kanai Makoto 
Published: August 2022

AbstractAimTo elucidate whether pregnancy and obesity are associated with poor sleep quality, and to investigate if sleep quality is associated with hypertensive disorders of pregnancy in pregnant women with obesity.MethodsThis observational cross‐sectional study examined 15 obese pregnant women (body mass index ≥30 kg/m2) (p‐Ob group), 15 nonobese pregnant women (p‐nOb group), and 30 nonobese nonpregnant women (n‐Pr group), using home recording devices to monitor sleep‐disordered breathing (SDB): respiratory disturbance index, oxygen saturation, and sleep stage and quality. These variables were compared among the groups. Moreover, obese women with and without hypertensive disorders of pregnancy were compared.ResultsSignificant differences in respiratory disturbance index (median: 10.3 [p‐Ob], 7.1 [p‐nOb], 3.5 [n‐Pr]) and oxygen saturation (95.1%, 96.5%, and 96.6%) were observed among the groups. Seven participants in the p‐Ob group experienced hypertensive disorders of pregnancy with SDB before or after sleep examination. Particularly, those who developed hypertensive disorders of pregnancy before sleep examination showed a lower delta power throughout the night than those without this condition.ConclusionPregnant women had poor sleep quality; those with obesity had higher frequency of SDB with worsened respiratory conditions that might cause complications. Our findings suggest that the development of hypertensive disorders of pregnancy in some obese pregnant women might be associated with insufficient delta power. Focusing on delta power may reflect subtle changes in sleep quality that occur in pregnant women. Future longitudinal studies with larger sample sizes are required to confirm these findings and investigate causality.
Young‐age exposure to armed conflict and women's experiences of intimate partner violence
Authors: Torrisi Orsola 
Published: August 2022

AbstractObjectiveThis study examines the legacy of experiencing armed conflict in childhood and adolescence on women's later risk of intimate partner violence (IPV) in four ex‐Soviet countries.BackgroundPrior research is largely concerned with male soldiers and perpetration, and rarely considers when, during the life course, conflict occurs. This study focuses on civilians, women's victimization and pays attention to the age at conflict exposure. This aspect is crucial to understand if war has lasting consequences for family violence, beyond contemporaneous effects. This paper further contributes by providing insights on driving mechanisms.MethodThe study combines cross‐national data on IPV from the Demographic and Health Surveys (N = 17,787) and geo‐referenced conflict information from the Uppsala Conflict Data Program. Using linear models with fixed effects, it compares the IPV outcomes of women exposed to conflict before the end of their teens with nonexposed peers and older women.ResultsYoung‐age conflict exposure is associated with greater adult IPV risk. Childhood exposure (ages 0–10) matters the most, especially for physical forms of IPV. Results are not driven by migration. Analyses of potential pathways show no relationship between war and changing marriage market conditions, or attitudes towards IPV in women. Conversely, men experiencing conflict in late adolescence (16–19) are more likely to condone violence against partners. Furthermore, women's childhood exposure to conflict correlates with having a violent father.ConclusionWar in young‐ages has long‐term implications for family violence. These appear in part related to greater exposure to family violence, and to a normalization of the use of violence in future potential perpetrators.
Kiss‐Up‐Kick‐Down to Get Ahead: A Resource Perspective on How, When, Why, and With Whom Middle Managers Use Ingratiatory and Exploitative Behaviours to Advance Their Careers
Authors: Gerpott Fabiola H. , Van Quaquebeke Niels 
Published: August 2022

AbstractThere are myriad organizational anecdotes about middle managers who advance their careers by ingratiating themselves with their superiors while exploiting and abusing their subordinates. We formally define this behavioural combination as the Kiss‐Up‐Kick‐Down (KUKD) phenomenon and develop a resource‐focused framework that not only explains when middle managers will engage in KUKD, but also how such behaviour helps their career progression via three resource‐related pathways: One path involving sponsorship resource gains from superiors, another path involving productive resource gains from subordinates, and an intra‐individual path related to middle managers' own psychological resources. Staying within the resource framework, we theorize that superiors and subordinates become likely targets of KUKD when the former is resource‐poor and the latter is resource‐rich. Finally, we deliberate on the role of time as a crucial boundary condition: not only in terms of when middle managers engage in KUKD behaviours, but also how such actions involve diminishing returns.
The Role of Intraoral Scanners in the Shade Matching Process: A Systematic Review
Authors: Akl Mohammed A. , Mansour Dina E. , Zheng Fengyuan 
Published: August 2022

AbstractPurposeThe variation in findings with regards to the accuracy and precision of intraoral scanners for shade selection are no doubt confusing for clinicians who may find it difficult to make evidence‐based decisions. The aim of this systematic review is to provide a comprehensive and in‐depth assessment of available studies to determine the viability of using intraoral scanners for the purpose of shade matching. The PICO‐guided research question is as follows: when shade matching, are intraoral scanners as valid as visual or other digital shade measuring devices in determining tooth colors.MethodsElectronic databases including PubMed/MEDLINE, SCOPUS, EBSCO, Cochrane, and ProQuest were systematically searched for articles published between January 1, 2011 and December 30, 2021 using the main search terms: “intraoral scanners,” “scanners,” “TRIOS,” “CEREC,” “Planmeca,” “Medit,” “digital dentistry” in concurrence with one of the following keywords: “EasyShade” OR “shade selection” OR “shade matching” OR “shade” OR “tooth color” OR “tooth shade” OR “digital shade matching.” Bibliographies of included articles and the following journals were searched for relevant articles: Journal of Prosthetic Dentistry, Journal of Prosthodontics, Journal of Esthetic and Restorative Dentistry, Journal of Advanced Prosthodontics, and Journal of Dentistry. A total of 15 articles were included in the review.ResultsIntraoral scanners are highly repeatable for shade matching, and outperformed visual shade matching. Accuracy varied significantly between studies, with the majority recommending the use of visual shade matching to confirm/verify the intraoral scanner results. Setting intraoral scanners to the Vita 3D Master shade guide improved both accuracy and precision. Shade matching with intraoral scanners may be influenced by external factors such as ambient light sources and incorrect use or manipulation.ConclusionIntraoral scanners set to the Vita 3D Master shade guide may be used for shade matching, but shade should be verified with visual shade matching. Further studies are required to address limitations of current studies.
Evidence for a conserved queen‐worker genetic toolkit across slave‐making ants and their ant hosts
Authors: Feldmeyer Barbara , Gstöttl Claudia , Wallner Jennifer , Jongepier Evelien , Séguret Alice , Grasso Donato A. , Bornberg‐Bauer Erich , Foitzik Susanne , Heinze Jurgen 
Published: August 2022

AbstractThe ecological success of social Hymenoptera (ants, bees, wasps) depends on the division of labour between the queen and workers. Each caste exhibits highly specialized morphology, behaviour, and life‐history traits, such as lifespan and fecundity. Despite strong defences against alien intruders, insect societies are vulnerable to social parasites, such as workerless inquilines or slave‐making ants. Here, we investigate whether gene expression varies in parallel ways between lifestyles (slave‐making versus host ants) across five independent origins of ant slavery in the “Formicoxenus‐group” of the ant tribe Crematogastrini. As caste differences are often less pronounced in slave‐making ants than in nonparasitic ants, we also compare caste‐specific gene expression patterns between lifestyles. We demonstrate a substantial overlap in expression differences between queens and workers across taxa, irrespective of lifestyle. Caste affects the transcriptomes much more profoundly than lifestyle, as indicated by 37 times more genes being linked to caste than to lifestyle and by multiple caste‐associated modules of coexpressed genes with strong connectivity. However, several genes and one gene module are linked to slave‐making across the independent origins of this parasitic lifestyle, pointing to some evolutionary convergence. Finally, we do not find evidence for an interaction between caste and lifestyle, indicating that caste differences in gene expression remain consistent even when species switch to a parasitic lifestyle. Our findings strongly support the existence of a core set of genes whose expression is linked to the queen and worker caste in this ant taxon, as proposed by the “genetic toolkit” hypothesis.
Content validity of a Safe Nursing Care Checklist for a neonatal unit
Authors: Manzo Bruna Figueiredo , Silva Daniela Cristina Zica , Fonseca Marina Pereira , Tavares Ingrid Vitória Ramalho , de Oliveira Marcatto Juliana , da Mata Luciana Regina Ferreira , Parker Leslie A. 
Published: August 2022

AbstractBackgroundNursing checklists have been shown to improve communication, reduce the occurrence of adverse events, and promote safe, quality care in different care settings. However, to date, there is no validated patient care safety checklist for nurses caring for infants in Neonatal Intensive Care Units (NICU).AimTo describe development and content validation of the “Safe Nursing Care Checklist for Infants Hospitalized in the Neonatal Intensive Care Unit”.Study DesignOnline Survey.MethodsBased upon an integrative literature review, we developed a checklist focused on safe nursing care for infants in the NICU. Nursing experts participated in three rounds of a content validation process where they rated the items online. An agreement level ≥0.90 was required for inclusion in the checklist. Forty‐ three expert nurses with experience working in the NICU and who were certified in neonatal nursing or had a master's or doctoratal degree in child health provided content validation of the patient care checklist.ResultsThe final checklist contained 45 items with content validation index scores greater than 90%. The instrument was structured into six dimensions including patient identification, effective communication, medication safety, infection prevention, fall prevention, and pressure injuries/skin injuries prevention.ConclusionContent validity was established for the “Safe Nursing Care Checklist for Infants Hospitalized in the Neonatal Intensive Care Unit” which can identify strengths and weaknesses in safe nursing care for infants in the NICU as well as direct educational interventions to promote nursing care based on scientific evidence.Relevance to Clinical PracticeThis checklist can potentially be used by bedside nurses to promote provision of safe care to infants in the NICU and to guide corrective strategies and encourage evidence‐based decision‐making. Validation in the clinical setting is needed.
The synergistic efficacy and safety of combined low‐concentration atropine and orthokeratology for slowing the progression of myopia: A meta‐analysis
Authors: Zheng Ning‐Ning , Tan Kai‐Wen 
Published: August 2022

AbstractPurposeTo explore the efficacy and safety of combined low‐concentration atropine and orthokeratology (OK) for slowing the progression of myopia.MethodsWe performed a systematic search of English and Chinese databases to collect potentially eligible randomised controlled trials (RCTs), nonrandomised controlled trials (non‐RCTs) and retrospective cohort studies (REs) published between the establishment of the database and 1 January 2022. The weighted mean difference (WMD) and 95% confidence interval (CI) were calculated for each outcome.ResultsFifteen studies were ultimately included in the meta‐analysis, which indicated that compared with OK lenses alone, the combination of low‐concentration atropine with OK lenses significantly slowed axial growth (WMD = −0.12 mm; 95% CI: −0.13 to −0.11, p < 0.001) and reduced the rate of change of the spherical equivalent refraction (WMD = 0.15 D; 95% CI: 0.06 to 0.24, p < 0.001). Additionally, the combined treatment may cause a slight increase in pupil diameter (WMD = 0.62 mm; 95% CI: 0.42 to 0.81, p < 0.001). No significant difference in the amplitude of accommodation, intraocular pressure, tear film break‐up time or corneal endothelial cell density was found between the OK and combination therapy groups.ConclusionsThe combination therapy of low‐concentration atropine and OK lenses had a greater effect in slowing myopia progression during a 6‐to‐12‐month treatment interval and was still effective over a 24‐month period. Increased pupil diameter was the major side effect of the combination therapy, with no negative impact on the amplitude of accommodation, intraocular pressure, tear film break‐up time or corneal endothelial cell density.
Lumps and bumps: What not to miss
Authors: Levin Laura E. , Kinariwalla Neha , Behr Gerald G. , Morel Kimberly D. , Lauren Christine T. , Garzon Maria C. 
Published: August 2022

AbstractThe evaluation of pediatric patients with subcutaneous nodules remains a diagnostic challenge. Pediatric dermatologists are regularly confronted with patients who have a nonspecific nodule. Though most masses that require evaluation are ultimately benign, the possibility of a more aggressive process, including borderline or malignant neoplasms, underscores the pivotal role of the pediatric dermatologist in recognizing these lesions. The aim of this review is to provide an overview of lumps and bumps that are important to recognize to prevent delay in diagnosis or treatment of a serious underlying condition. Clinical clues that may lead the pediatric dermatologist to have a higher index of suspicion for more aggressive lesions are reviewed. Suggestions for evaluation and workup, as well as tips for the difficult to discern lesion, are proposed.
Transcriptome analysis reveals candidate genes related to steroid alkaloid biosynthesis in Fritillaria anhuiensis
Authors: Shan Tingyu , Shi Yuanyuan , Xu Jingyao , Zhao Liqiang , Tao Yijia , Wu Jiawen 
Published: August 2022

AbstractFritillaria anhuiensis (F. anhuiensis), a traditional medicinal herb of the Liliaceae family, has various pharmacological effects, including anti‐tussive, anti‐asthmatic, and expectorant activities. Peimine, a steroidal alkaloid, is a major active constituent of F. anhuiensis. Although steroidal alkaloids of F. anhuiensis have been explored chemically and pharmacologically, the molecular basis of their biosynthesis remains unknown due to a lack of genomic and transcriptomic information. In this study, peimine was detected in bulbs, stems, and leaves of F. anhuiensis, with the highest content in the bulbs. We analyzed the transcriptomes of the bulbs, stems, and leaves of F. anhuiensis using an Illumina HiSeq 4000 platform. A total of 92,829 unigenes with a mean length of 804 base pairs (bp) and an N50 value of 1354 bp were assembled from a total of 30.56 Gb high‐quality reads. Based on the Kyoto Encyclopedia of Genes and Genomes annotation, 83 unigenes were found to be related to the steroid biosynthesis pathway, while 155 unigenes were related to the terpenoid backbone biosynthesis pathway. Numerous transcription factors are involved in the regulation of alkaloid biosynthesis. A putative steroidal alkaloid biosynthesis pathway in F. anhuiensis was constructed, providing a novel understanding of peimine biosynthesis. We performed extensive bioinformatics and phylogenetic analyses to investigate the functional characteristics and evolutionary history of cycloartenol synthase. This study is the first to report transcriptome data from F. anhuiensis and extends our knowledge of the molecular mechanisms of steroid alkaloid biosynthesis.