bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic properties of the Italian ECAS Carer Interview (ECAS-CI)
Authors: Poletti Barbara , Aiello Edoardo Nicolò , Solca Federica , Torre Silvia , Carelli Laura , Ferrucci Roberta , Verde Federico , Ticozzi Nicola , Silani Vincenzo 
Published: November 2022

AbstractBackgroundThis study aimed at providing diagnostic properties and normative cut-offs for the Italian ECAS Carer Interview (ECAS-CI).MaterialsN = 292 non-demented ALS patients andN = 107 healthy controls (HCs) underwent the ECAS-CI and the Frontal Behavioural Inventory (FBI). Two ECAS-CI measures were addressed: (1) the number of symptoms (NoS;range = 0–13) and (2) that of individual symptom clusters (SC;range = 0–6). Diagnostics were explored against an FBI score ≥ than the 95th percentile of the patients’ distribution.ResultsBoth the NoS and SC discriminated patient from HCs. High accuracy, sensitivity, and specificity were detected for both the NoS and SC; however, at variance with SC, the NoS showed better post-test features and did not overestimate the occurrence of behavioural changes. The ECAS-CI converged with the FBI and diverged from the cognitive section of the ECAS.DiscussionThe ECAS-CI is a suitable screener for behavioural changes in ALS patients, with the NoS being its best outcome measure (cut-off: ≥ 3).
Simultaneous removal of inorganic and organic pollutants from multicomponent solutions by the use of zeolitic materials obtained from fly ash waste
Authors: Medykowska Magdalena , Wiśniewska Małgorzata , Szewczuk-Karpisz Katarzyna , Panek Rafał , Franus Małgorzata 
Published: November 2022

Abstract
Fly ash is an energy waste considered as a global environmental hazard. Annually, it is generated in the amount of over 50 million tons. One of the ways of fly ash management is its conversion into porous structures, which then can be applied to capture other pollutants from the aquatic environment. This paper presents the adsorption capabilities of four products of hydrothermal reaction of fly ash (HC FA), i.e., zeolites (Na-X, NA-P1) and their composites with carbon (Na-X(C), Na-P1(C)). All five materials were characterized in terms of their structure and used as adsorbents of heavy metals (Pb(II), Zn(II) ions) and organic compounds (diclofenac – popular anti-inflammatory drug, poly(acrylic acid) – polymer commonly used in industry) from their mixed solutions. Adsorption–desorption, electrokinetic and stability measurements were performed to determine the mechanisms driving the formation of the mixed adsorption layers. It was found that Na-X zeolite adsorbed 322.1 mg/g of Pb(II), 332.5 mg/g of Zn(II) and 6.68 mg/g of DCF, whereas Na-P1 bounded 332.9 mg/g of Pb(II), 103.6 mg/g of Zn(II) and 21.19 mg/g of DCF. In the mixed systems of adsorbates, these values were different, but also satisfactory. For example, in the Zn(II) presence, the adsorption of DCF on Na-X increased from 6.68 to 12.86 mg/g and that on Na-X(C), from 8.49 to 21.95 mg/g. The adsorbed pollutants changed the structure of electrical double layer of zeolitic materials. Moreover, they affected the stability of the examined suspensions. The presented results are promising for the further application of obtained zeolitic materials for environmental remediation.

Graphical Abstract
Deep Learning-based Non-rigid Image Registration for High-dose Rate Brachytherapy in Inter-fraction Cervical Cancer
Authors: Salehi Mohammad , Vafaei Sadr Alireza , Mahdavi Seied Rabi , Arabi Hossein , Shiri Isaac , Reiazi Reza 
Published: November 2022

Abstract
In this study, an inter-fraction organ deformation simulation framework for the locally advanced cervical cancer (LACC), which considers the anatomical flexibility, rigidity, and motion within an image deformation, was proposed. Data included 57 CT scans (7202 2D slices) of patients with LACC randomly divided into the train (n = 42) and test (n = 15) datasets. In addition to CT images and the corresponding RT structure (bladder, cervix, and rectum), the bone was segmented, and the coaches were eliminated. The correlated stochastic field was simulated using the same size as the target image (used for deformation) to produce the general random deformation. The deformation field was optimized to have a maximum amplitude in the rectum region, a moderate amplitude in the bladder region, and an amplitude as minimum as possible within bony structures. The DIRNet is a convolutional neural network that consists of convolutional regressors, spatial transformation, as well as resampling blocks. It was implemented by different parameters. Mean Dice indices of 0.89 ± 0.02, 0.96 ± 0.01, and 0.93 ± 0.02 were obtained for the cervix, bladder, and rectum (defined as at-risk organs), respectively. Furthermore, a mean average symmetric surface distance of 1.61 ± 0.46 mm for the cervix, 1.17 ± 0.15 mm for the bladder, and 1.06 ± 0.42 mm for the rectum were achieved. In addition, a mean Jaccard of 0.86 ± 0.04 for the cervix, 0.93 ± 0.01 for the bladder, and 0.88 ± 0.04 for the rectum were observed on the test dataset (15 subjects). Deep learning-based non-rigid image registration is, therefore, proposed for the high-dose-rate brachytherapy in inter-fraction cervical cancer since it outperformed conventional algorithms.
Plant species selection and impact on tree resprouts by semi-free ranging pigs in a temperate deciduous forest
Authors: Nota Ginevra , Berretti Roberta , Ascoli Davide , Barberis Davide , Ravetto Enri Simone , Pittarello Marco , Motta Renzo , Battaglini Luca Maria , Lombardi Giampiero , Lonati Michele 
Published: November 2022

AbstractSilvopastoral systems with grazing pigs are mainly concentrated in Mediterranean regions, for instance in Iberian dehesas and montados. Conversely, in European deciduous forests, outdoor pig farming has almost disappeared, despite it could provide several environmental and socioeconomic benefits. For instance, pig grazing could be used for habitat restoration and conservation, while providing high quality meat products and promoting local breeds. In this study, we investigated (i) the plant species selection and (ii) the impact on tree resprouts (after a silvicultural cut) by semi-free ranging pigs in a degraded oak temperate forest in Northwestern Italy. We monitored pigs foraging behavior by direct observations and discriminated the plant species into three groups: preferred, indifferently consumed and avoided plants. The impact on the resprouts of six tree species was assessed by modeling the percentage of damaged shoots and their height through time using Generalized Linear and Additive Mixed Models. Swine expressed a selective foraging behavior, which was likely influenced by the forage quality and toxicity of plant species. The leaves and resprouts of Corylus avellana and Castanea sativa were highly consumed, whereas Acer and Quercus species and Fraxinus ornus were avoided. Mature leaves of Robinia pseudoacacia were highly preferred while its young resprouts were only slightly impacted, suggesting that pig grazing may not be effective to control this alien invasive species. Contrarily, pigs consumed Rubus sp. abundantly, suggesting they could be used to clear the understory in degraded forests.
Heart Rate Variability: A Measure of Cardiovascular Health and Possible Therapeutic Target in Dysautonomic Mental and Neurological Disorders
Authors: Siepmann Martin , Weidner Kerstin , Petrowski Katja , Siepmann Timo 
Published: November 2022

AbstractMental illness such as depression and anxiety as well as cerebrovascular disease are linked to impairment of neurocardiac function mediated by changes to the autonomic nervous system with increased sympathetic and decreased parasympathetic activity. Autonomic neurocardiac function can be evaluated by computing heart rate variability (HRV). Over the past decades, research has demonstrated the diagnostic value of HRV as independent predictor of cardiovascular mortality and as disease marker in progressive autonomic nervous system disorders such as Parkinson’s disease. Here we summarize our studies on HRV and its therapeutic modulation in the context of psychopharmacology as well as psychiatric and neurological disorders to honor the life of Professor Evgeny Vaschillo, the true pioneer of HRV research who sadly passed away on November 21st, 2020.
Prognosis of local invasive relapses after carcinoma in situ of the breast: a retrospective study from a population-based registry
Authors: Kada Mohammed Samia , Dabakuyo Yonli Tienhan Sandrine , Desmoulins Isabelle , Manguem Kamga Ariane , Jankowski Clémentine , Padeano Marie-Martine , Loustalot Catherine , Costaz Hélène , Causeret Sylvain , Peignaux Karine , Rouffiac Magali , Coutant Charles , Arnould Laurent , Ladoire Sylvain 
Published: November 2022

Abstract
Purpose
The prognosis of local invasive recurrence (LIR) after prior carcinoma in situ (CIS) of the breast has not been widely studied and existing data are conflicting, especially considering the specific prognosis of this entity, compared to de novo invasive breast cancer (de novo IBC) and with LIR after primary IBC.

Methods
We designed a retrospective study using data from the specialized Côte d’Or Breast and Gynecological cancer registry, between 1998 and 2015, to compare outcomes between 3 matched groups of patients with localized IBC: patients with LIR following CIS (CIS-LIR), patients with de novo IBC (de novo IBC), and patients with LIR following a first IBC (IBC-LIR). Distant relapse-free (D-RFS), overall survival (OS), clinical, and treatment features between the 3 groups were studied.

Results
Among 8186 women initially diagnosed with IBC during our study period, we retrieved and matched 49 CIS-LIR to 49 IBC, and 46 IBC-LIR patients. At diagnosis, IBC/LIR in the 3 groups were mainly stage I, grade II, estrogen receptor-positive, and HER2 negative. Metastatic diseases at diagnosis were higher in CIS-LIR group. A majority of patients received adjuvant systemic treatment, with no statistically significant differences between the 3 groups. There was no significant difference between the 3 groups in terms of OS or D-RFS.

Conclusion
LIR after CIS does not appear to impact per se on survival of IBC.
Controlling superstructure formation and macro-scale adhesion via confined evaporation of cellulose nanocrystals
Authors: Borrero-López Antonio M. , Greca Luiz G. , Rojas Orlando J. , Tardy Blaise L. 
Published: November 2022

AbstractThe self-assembly of cellulose nanocrystals can tether their interfacial interactions and the associated properties of their constructs. For instance, assemblies of highly aligned cellulose nanocrystals (CNCs) bear improved mechanical strength, barrier properties, and piezoelectric response. In this study, the self-assembly of CNC superstructure was assessed under various confinement geometries, enabling optimization of the long-range order within the microstructures formed. The confinement involved the planar capillary (with a rectangular cross-section)formed between two glass substrates with silicone boundaries. The impact of temperature, width and thickness of the capillary plane on self-assembly of the micro-scaled lamellar structures was evaluated. Thinner capillaries and lower temperatures were found to considerably improve long-range order and increase the frequency of the periodic microstructures formed. The drying process was monitored by rheological analysis, which showed an initial fast drying followed by slow drying due to the hindered diffusion through lamellae. The adhesive properties of the formed superstructures were evaluated. The shear strength was shown to depend on the orientation of the superstructures and therefore of the CNCs. About 4 MPa adhesion strength was obtained when the lamellar superstructures were perpendicularly aligned with respect to the in-plane force applied, while ca. 3 MPa adhesion was obtained for parallel alignment. The experimental framework described herein enabled the evaluation of the impact of the dimensions of a drying meniscus on self-assembly of anisometric colloids while also linking cellulosic assemblies with their interfacial supramolecular interactions. This simple framework brings forward the possibility to correlate the behavior of nanometric objects with micro- and macro-scaled observations, e.g., macro-scaled mechanics of adhesion.
Intention to purchase sustainable craft products: a moderated mediation analysis of the adoption of sustainability in the craft sector
Authors: Prados-Peña María Belén , Gálvez-Sánchez Francisco Jesús , Núñez-Cacho Pedro , Molina-Moreno Valentín 
Published: November 2022

AbstractIn the modern world, the management of companies has evolved from a model characterized by the extraction, transformation, and generation of waste towards a more sustainable model. This transition affects even more traditional sectors, such as crafts. A key aspect of the transition towards more sustainable models is knowledge of the disposition of consumers with respect to these new artisan products. To date, few works have addressed this research problem, so this paper analyses consumer behaviour towards sustainable craft products empirically. To accomplish this goal, the effect of the image of sustainable craft products as perceived by consumers on their purchase intention is studied. Attitudes towards sustainable crafts, purchase intention, degree of consumer involvement and degree of knowledge concerning sustainability are considered as moderating variables. A questionnaire was distributed to a sample of handicraft consumers, and confirmatory factor analysis and an ordinary least squares regression model were used to study the data thus obtained. The results showed that the image of sustainable craft products as perceived by consumers influences their purchase intentions. In addition, this influence is increased when consumer attitudes towards and involvement with sustainable craft products increase. The results of this study can be useful for the sustainable crafts sector with respect to incorporating more sustainable products and designing marketing and communication strategies to help consumers learn about sustainability.
A Grammarian’s View of Negation: Nāgeśa’s Paramalaghumañjūs.ā on Nañartha
Authors: Lowe John J. , Benson James W. 
Published: November 2022

AbstractThe theory of negation developed in the grammatical-philosophical system of later Vyākaraṇa remains almost entirely unstudied, despite its close links with the (widely studied) approaches to negation found in other philosophical schools such as Nyāya and Mīmāṃsā, and despite its consequent importance for a comprehensive understanding of the theory of negation in ancient India. In this paper we present an edition, translation and commentary of the relevant sections of Nāgeśa’s Paramalaghumañjūṣā, a concise presentation by the final authority of the Pāṇinian tradition, together with an explanatory introduction outlining the grammarians’ theory of negation and its relations particularly with the Nyāya theory of negation.
Clinical observation of radiofrequency ablation for premature ventricular contractions originating from uncommon His-Purkinje sites
Authors: Huang Jing , Zhao Yidong , Yang Long , Liu Qifang 
Published: November 2022

Abstract
Background
Radiofrequency catheter ablation (RFCA) of premature ventricular contractions (PVCs) originating from common locations such as the proximal and middle fascicles of the His-Purkinje system (HPS) has been established as an effective therapy. This report aims to highlight the electrophysiological properties and RFCA of PVCs originating from uncommon locations of the HPS.

Methods
Among 57 patients with fascicular PVCs, 3 with fascicular PVCs originating from uncommon sites were retrospectively analyzed.

Results
We identified three patients with PVCs originating separately from diseased fascicles, the dead-end tract (DET), and the distal fascicle. In contrast to PVCs originating from the proximal and medial fascicles, the fascicular potentials could not be recorded at the target sites of patients with PVCs originating from diseased fascicles or the distal fascicle during sinus rhythm. However, these PVCs were successfully ablated from the HPS, guided by recording their earliest fascicular potentials in PVCs. PVCs originating from the DET are morphologically consistent with those originating from the proximal left anterior fascicle or the distal left bundle branch. The corresponding tiny sharp potential of the DET could be mapped, and RFCA of the right coronary cusp achieved successful suppression of PVCs.

Conclusions
The knowledge of the different electrophysiological characteristics of fascicular PVCs originating from uncommon locations can contribute to precise mapping and ablation. For such arrhythmia, the target site for successful ablation should be identified by earliest fascicular potential.
Policy Engagement Framework for Public Health: A Tool to Enhance Maternal and Child Health Workforce Capacity
Authors: Branscomb Jane , Powis Laura , Cilenti Dorothy , Dills James E. , Chaudhry Atyya 
Published: November 2022

Abstract
Purpose
This paper proposes a framework for characterizing policy engagement that expands options available to MCH and other public health professionals. Its aim is to inform workforce capacity building and empower practitioners to better leverage policy for advancing population health and equity.

Description
Policies of all types strongly influence population health and equity. Recognizing this, public health leaders identify policy engagement skills as key for public health professionals generally, and for maternal and child health (MCH) professionals specifically. Practitioners likewise see the importance of these skills and report deficiencies in them. Despite this gap, no literature to-date itemizes the range of policy engagement possibilities for public health professionals.

Assessment
The Policy Engagement Framework for Public Health addresses this gap by providing a language and organizing structure for the numerous ways engagement may take shape. The possibilities are combinations of a particular target policy source (the what) and jurisdiction (the where), a policy process phase (the when), and an engagement role (the how). Policy source and jurisdiction are broken down to highlight the many types to consider for a given topic and population. Established public health constructs are adapted to enumerate policy phases and public health roles.

Conclusions for Practice
The Policy Engagement Framework can enhance workforce capacity by expanding mindsets about ways public health and MCH practitioners can consider engaging. It can facilitate communication and clarity within an organization regarding what activities are permitted in staff’s official capacity. Finally, it can guide the strategic development of workforce education and training.
Terms used to describe and define activities undertaken as a result of the medication review process: Do they require standardisation? A systematic review
Authors: Alharthi Mohammed , Wright David , Scott Sion , Blacklock Jeanette 
Published: November 2022

Abstract
Background
Medication review (MR) is the systematic assessment of a patient’s medications by a healthcare practitioner. It is necessary to compare such MR interventions to rationalise differences between them and assess their impact. The development of an international taxonomy for terms used to describe activities undertaken within the MR process would facilitate quality of reporting, and the comparison of different interventions.

Aim
To identify overarching and individual MR activity terms and definitions reported within studies where MR was the main intervention.

Method
A systematic review of the literature was performed using search terms for ‘Intervention’ and ‘Outcome’. Papers with empirical data reporting and describing MR activities in English were included. The Mixed Method Appraisal Tool was used to assess research quality. Two researchers reviewed all included literature independently. Data extraction was performed using Cochrane Effective Practice and Organisation of Care to report study characteristics, and terms and definitions used to describe MR activities.

Results
Twenty-one papers were included: eight quantitative non-randomised trials (38%), eight randomised controlled trials (38%), and five quantitative descriptive studies (24%). Overarching interventions such as ‘Clinical’, ‘Education’ and ‘Technical’ were identified with no standardised definitions. Terms used to describe the medication review activities, such as stop, start and change, varied with significant potential for ambiguity.

Conclusion
The literature reports a variety of overlapping, ambiguous and undefined MR terms. As a result, comparing process evaluations from MR interventions may be difficult. A standardised taxonomy to describe, define and report MR activities is required.
A lineage explanation of human normative guidance: the coadaptive model of instrumental rationality and shared intentionality
Authors: Gonzalez-Cabrera Ivan 
Published: November 2022

AbstractThis paper aims to contribute to the existing literature on normative cognition by providing a lineage explanation of human social norm psychology. This approach builds upon theories of goal-directed behavioral control in the reinforcement learning and control literature, arguing that this form of control defines an important class of intentional normative mental states that are instrumental in nature. I defend the view that great ape capacities for instrumental reasoning and our capacity (or family of capacities) for shared intentionality coadapted to each other and argue that the evolution of this capacity has allowed the representation of social norms and the emergence of our capacity for normative guidance.
Thermoelastic Stress Measurement Using SVD Thermo-Component Analysis
Authors: Uchida Y. , Kanade T. , Shiozawa D. , Sakagami T. 
Published: November 2022

Abstract
Background
In self-correlation lock-in thermography for thermoelastic stress analysis (TSA), the acquisition position of the reference signal affects the accuracy of the obtained stress amplitude distribution. When the reference signal is not large enough compared to the noise, the stress amplitude distribution may be incorrect.

Objective
This study proposes a method that does not require a reference signal and frequency analysis to obtain the stress amplitude distribution with comparable or higher accuracy than that obtained using self-correlation lock-in thermography.

Methods
An observation matrix is generated from the temporal variation across all thermographic pixels to describe the thermal fluctuations due to stress. Thereafter, stress amplitude distribution and the original load signal are extracted from the observation matrix using singular value decomposition (SVD). The proposed method is called SVD thermo-component analysis. To investigate the effectiveness of the proposed method, the reconstructed load signal and stress distribution are obtained from the captured thermal images for the specimen under a sinusoidal load.

Results
The stress amplitude distribution obtained using the proposed method is equivalent to that obtained using conventional lock-in thermography with the original load signal as the reference signal. In addition, the reconstructed load signal obtained using the proposed method successfully represents the original load signal.

Conclusions
SVD thermo-component analysis does not require prior knowlege of the evaluated mechanical structure to select a suitable reference-signal acquisition position as in self-correlation lock-in thermography. Therefore, the proposed TSA method reduce analysis failures compared to the conventional method.