bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of skin graft donor site management using oxidised regenerated cellulose (ORC)/collagen/silver‐ORC with absorptive silicone adhesive border and transparent film dressing vs semi‐occlusive dressings
Authors: Chowdhry Saeed A. 
Published: September 2022

AbstractSplit‐thickness skin grafts (STSG) are widely used in wound reconstruction. However, donor site wounds are created as a result. Traditionally, moist wound healing and transparent film dressings have been used to promote donor site wound healing. This retrospective study evaluated the use of oxidised regenerated cellulose (ORC)/collagen/silver‐ORC dressing (ORC/C/Ag‐ORC) with an absorptive silicone adhesive border dressing and transparent film dressing (treatment) compared with petrolatum‐based gauze dressing (control) over donor site wounds. Patients underwent an STSG procedure between January and December 2020. Donor sites received treatment (n = 10) or control (n = 10) dressings. Dressing changes occurred as necessary. Time to epithelialisation, narcotic pain medication requirements, and the number of office/hospital visits were examined. Twenty patients were managed (9 males, 11 females, average age: 49.7 ± 13.9 y). Patient comorbidities included hypertension, diabetes, and hyperlipidemia. Wound types included traumatic and cancer excision. Time to epithelialisation was significantly reduced in the treatment group (11.1 ± 1.4 d vs 18 ± 2.4 d, P < 0.0001). The number of office visits for dressing changes was significantly lower in the treatment group (0.1 ± 0.3 vs 2 ± 0.7, P < 0.0001). No patients in the treatment group required a hospital visit, compared with 3 patients in the control group. One patient in the treatment group required narcotic pain medication, compared with 5 in the control group. In this patient population, the use of ORC/C/Ag‐ORC, an absorptive silicone adhesive border dressing, and transparent film dressing resulted in a shorter time to epithelialisation and less analgesic requirement compared with petrolatum‐based gauze dressing use.
Caregiving and future planning perspectives of siblings of individuals with intellectual and developmental disabilities: Insights from South Korea, Japan and Taiwan
Authors: Lee Chung Eun , Hagiwara Mayumi , Chiu Chun‐Yu , Takishima Mayu 
Published: September 2022

AbstractBackgroundAs individuals with intellectual and developmental disabilities age, their siblings are more likely to assume caregiving responsibilities. However, little is known about experiences of East Asian siblings with respect to their caregiving and future‐planning within their own country, as well as other East Asian countries.MethodsUsing a national survey, this study explored experiences of 576 siblings across South Korea, Japan and Taiwan.ResultsA common factor across the three countries was that siblings were less engaged in advocacy and future‐planning activities and felt less competent to play the role of caregiving. Korean siblings reported more negative views about disability, while Japanese siblings reported less engagement in future‐planning and Taiwanese siblings reported greater involvement in caregiving.ConclusionBased on ‘universalism without uniformity’, it is recommended to develop culturally sensitive sibling‐targeted intervention based on each country's context.
Porokeratosis is one of the most common genodermatoses and is associated with an increased risk of keratinocyte cancer and melanoma
Authors: Inci Rahime , Zagoras Theofanis , Kantere Despoina , Holmström Peter , Gillstedt Martin , Polesie Sam , Peltonen Sirkku 
Published: September 2022

AbstractBackgroundPorokeratosis is a clinically heterogeneous group of keratinization disorders with a genetic background mainly affecting the mevalonate pathway, which is involved in the synthesis of cholesterol, an essential component for the formation of the extracellular lipid lamellae in the stratum corneum. Porokeratosis is reportedly associated with an increased risk of keratinocyte cancer, but to date, no large epidemiological studies have been conducted to further address this association.ObjectivesThe first objective was to characterize a cohort of patients diagnosed with porokeratosis at the Department of Dermatology and Venereology, Sahlgrenska University Hospital (SU), Gothenburg, Sweden. The second objective was to conduct a nationwide registry‐based cohort study to investigate the association, if any, between porokeratosis and the cutaneous malignancies squamous cell carcinoma (SCC), basal cell carcinoma (BCC) and melanoma.MethodsFor the SU cohort, the hospital registry was searched for patients with a diagnosis of porokeratosis recorded between 2016 and 2020. Clinical data were extracted from the records of the identified patients. For the nationwide cohort, national registries were searched to identify patients with a diagnosis of porokeratosis between 2001 and 2020. A tenfold control cohort was formed by Statistics Sweden. The data was cross‐referenced with the Swedish Cancer Register to study the associations between porokeratosis and SCC, BCC and melanoma.ResultsDisseminated superficial actinic porokeratosis was the most common clinical type among the 108 patients in the SU cohort. In the nationwide search, 2277 patients with porokeratosis were identified (prevalence 1/4132). Porokeratosis was associated with an increased risk for SCC, BCC and melanoma with hazard ratios (95% CI) of 4.3 (3.4–5.4), 2.42 (1.97–2.98) and 1.83 (1.18–2.82), respectively, in the patient cohort, compared to the matched control group.ConclusionPorokeratosis is a common genodermatosis, and it is associated with an enhanced risk of skin cancer.
Risk analysis of systemic side effects of tumescent local anaesthesia in the surgical treatment of geriatric and multimorbid patients with skin cancer
Authors: Schnabl Saskia Maria , Garbe Claus , Breuninger Helmut , Walter Vincent , Aebischer Valentin , Eckardt Julia , Ghoreschi Franziska Carola , Häfner Hans‐Martin , Scheu Alexander 
Published: September 2022

AbstractBackgroundDue to demographic change and increased UV exposure, the number of dermatosurgical procedures in the elderly is increasing. Data on the occurrence of systemic side effects during and after treatment with tumescent local anaesthesia are limited and do not refer to details such as volume and composition of local anaesthetics or epinephrine additive.ObjectivesThe aim of this study was to investigate the risk of systemic side effects in elderly patients undergoing skin tumour surgery with tumescent local anaesthesia.MethodsInvestigation of systemic complications in patients (≥75 years) who underwent head and neck skin tumour surgery under tumescent local anaesthesia at the Department of Dermatology, University Medical Centre Tübingen, between October 2018 and March 2020.ResultsIn total 782 patients (479 males, 303 females) with a mean age of 83.3 years (range: 75.1–102.2 years) could be included. A total of 2940 procedures were performed. Patients were assigned to two groups. The old–old group (≥75–84 years) included 491 patients and the oldest–old group (≥85 years) included 291 patients. The total inpatient stay and thus mean follow‐up period was 4.9 days (range 1–28 days). 92.0% (719/782) suffered from pre‐existing comorbidities. Systemic complications occurred in 10.2% (80/782; old–olds: 8.6%, oldest–olds: 13.1%). Hypertensive crisis (>180/120 mmHg) requiring intervention (6.7%) that occurred intraoperatively or during the inpatient stay was the most frequent systemic complication. Cardiac arrhythmias occurred postoperatively in 0.8% of cases. No life‐threatening complications directly related to tumescent local anaesthesia were found.ConclusionsSkin tumour surgery in tumescent local anaesthesia for the elderly is safe, and complications caused by general anaesthesia can be avoided. Systemic complications can occur, but are usually mild, are caused by pre‐existing diseases and perioperative excitement, and can be rapidly detected and well treated by monitoring. There is no direct correlation of complications to high‐tumescent concentrations or volume quantities.
Impact of roasting degree on sensory profile of Turkish coffee and espresso assessed by Turkish and Brazilian panelists
Authors: Elmaci Ilkay , Gok Ilkay , Tokusoglu Ozlem 
Published: September 2022

AbstractThis study aimed to assess the effect of roasting degree and brewing techniques on the sensory profile of Turkish coffee and espresso. Descriptive analysis of coffee samples was carried out for 20 flavor attributes by 10 Turkish and 10 Brazilian assessors. Light, medium, and dark roasted coffee beans were brewed with the decoction method and pressure method. Turkish coffee samples were prepared by automatic machine and cezve, which is the traditional method. The roasting degree and brewing method had a significant impact on the sensory profile of coffee samples. Turkish assessors perceived lightly roasted coffee beverages as sour (6.53 and 6.56 for Turkish coffee with machine and espresso) and pungent notes (7.46 for espresso), while Brazilian assessors perceived them as fruity (5.63 for espresso) and sweet attributes (5.76 and 5.90 for Turkish coffee with cezve and espresso). Roasted (7.83), burnt/acrid (7.96), and bitter (8.13) notes became dominant with the degree of roasting in espresso coffees in the Turkish panel. Brazilian assessors perceived Turkish coffee samples made with cezve and dark roasted beans as roasted (6.53), burnt/acrid (6.66), bitter (6.80), and ashy‐sooty (7.26) notes.Practical applicationsThis research indicates the effect of cultural experience, the degree of roasting, and brewing techniques on the sensory profile of coffee brews. Cultural familiarity and unfamiliarity with Turkish coffee and espresso played an important role in the perceptions of the participants. Variations in descriptive analysis between two country panelists may arise from language and ethnicity differences, oral physiological parameters such as the sensitivity of the somatosensory system, the culinary culture, and eating habits. For the first time, Turkish coffee and espresso coffee brewing techniques were compared by trained Turkish and Brazilian assessors.
Dismantling the master's house: Epistemological tensions and revelatory interventions for reimagining a transformational family science
Authors: Jones Janine , Hunter Andrea G. , Tarver Shuntay Z. 
Published: September 2022

AbstractUsing Audre Lorde's The Master's Tools as an epistemic guide, we propose two practice interventions for family science (FS) transformative praxes. The first, inspired by the thought of philosopher Charles Mills, challenges FS practitioners (research, practice, and policy) to explore differences in peripheral and positivist & post‐positivist (P&PP) ideologies responsible for differences in beliefs regarding the salience or non‐salience of power differentials within FS. The second, inspired by the thought of philosopher Rudolph Carnap, encourages FS practitioners to consider differences in peripheral and P&PP practitioners' understandings of what FS is at its core, and the beliefs and actions guided by their divergent core understandings. Both revelatory practices are intended to transform FS in such a way that its praxes are informed by these ways of practicing, and so that embodied understandings of the importance of pursuing anti‐racist and social justice objectives within FS become manifest.
Plant‐based meats in China: a cross‐sectional study of attitudes and behaviours
Authors: Chung Jah Ying , Bryant Christopher J. , Asher Kathryn E. 
Published: September 2022

AbstractBackgroundThis study investigated potential opportunities or challenges for plant‐based meat in the Chinese market. A quantitative framework was applied to determine the current level of familiarity and experience with plant‐based meat among Chinese consumers, the proportion of consumers who would try or purchase plant‐based meat, which demographics within China are most likely to buy plant‐based meat and which attitudes are important in driving the purchase intent of plant‐based meat.MethodsA pre‐registered cross‐sectional online survey (N = 1206) was distributed to respondents (matched to China's adult population for gender and age).ResultsRespondents reported a variety of dietary identities, with 43.4% reporting that they were reducing or avoiding meat. The majority of respondents (60.1%) said they had eaten plant‐based meat at least once before. Of those who said they had never eaten plant‐based meat, 41.9% intended to try it and 31.4% intended to purchase it. The strongest attitudinal predictor of plant‐based meat purchase intent was perceived healthiness (β = 0.235, p < 0.001), whereas the strongest demographic predictor of plant‐based meat purchase intent was age (β = −0.248, p < 0.001).ConclusionsThe findings of this study suggest that an approach based on increasing opportunities for trial, as well as appealing to specific attitudinal and demographic predictors of plant‐based purchase intent, could prove successful in increasing adoption of plant‐based and alternative meat products.
A European update on transcatheter aortic valve implantation (TAVI) in the COVID era
Authors: Antony Ishan , Mehari Abraha Hyab , Hameed Aamir , Conway Claire 
Published: September 2022

AbstractMinimally invasive approaches for aortic valve replacement are now at the forefront of pathological aortic valve treatment. New trials show comparability of these devices to existing therapies, not only in high‐risk surgical cohorts but also in low‐risk and intermediate‐risk cohorts. This review provides vital clinical and anatomical background to aortic valvular disease treatment guidelines, while also providing an update on transcatheter aortic valve implantation (TAVI) devices in Europe, their interventional trials and associated complications.
Evaluation of clinical efficacy and laboratory indicators of non‐cultured epidermal cell suspension and hair follicle cell suspension in surgical management of stable vitiligo: A randomized comparative trial
Authors: Challa Apoorva , Chauhan Suman , Pangti Rashi , Arava Sudheer Kumar , Prajapati Sapna , Pandey Anjali , Gupta Somesh 
Published: September 2022

AbstractBackgroundNon‐cultured epidermal cell suspension (ECS) and hair follicle cell suspension (HFCS) are well‐established methods of surgical treatment of stable vitiligo.AimsThe aim of the present study was to compare the laboratory indicators and clinical efficacy of ECS and HFCS in the treatment of stable vitiligo.MethodsThis was a single centre, open‐labeled randomized trial. Vitiligo patches from 74 patients were randomized to receive either ECS or HFCS. Both cell suspensions were analyzed for total cell count, cell viability and melanocyte count. Percentage re‐pigmentation was assessed at regular intervals for 36 weeks.ResultsThe percentage re‐pigmentation with ECS was significantly higher than HFCS at week 4 (p = .01) and week 16 (p = .03) however, no difference was observed at weeks 24 (p = .38) and 36 (p = .05). Forty‐seven patients completed the study follow‐up duration and excellent re‐pigmentation (>90%) was achieved in 61.7% and 53.2% and complete re‐pigmentation (100%) was observed in 6.4% and 12.8% of participants using ECS and HFCS, respectively. Significantly higher cell yield (p < .01) and percentage of HMB45+ melanocytes (p = .01) were obtained using ECS. No difference was noted in the percentage of viable cells or S100 + melanocytes.ConclusionThe median cell yield was eight times higher in ECS than in HFCS with a significantly higher percentage of HMB45+ melanocytes in the former group. The median percentage of re‐pigmentation in both groups was 90% at the end of 36 weeks. ECS provides faster re‐pigmentation; however, both ECS and HFCS have comparable safety and efficacy over a longer duration of follow‐up.
What guy wouldn't want it? Male victimization experiences with female‐perpetrated stranger sexual harassment
Authors: Erentzen Caroline , Salerno‐Ferraro Alisha C. , Schuller Regina A. 
Published: September 2022

AbstractThe present research explored female‐perpetrated stranger sexual harassment of young male victims. Across two studies, male participants aged 16–23 reported that they had experienced a range of unwanted sexual attention from unknown female perpetrators, including both in‐person harassment (e.g., seductive behavior and catcalls, unwanted sexual touching) and online harassment (e.g., unsolicited sexual text messages and images, requests for nude self photos). Participants reported that in‐person sexual harassment started as early as 9–12 years of age and online harassment began between 12–14 years of age. Open‐ended descriptions of these early events revealed troubling narratives of non‐consensual sexual touching, forcibly removed clothing, groping, aggression, and being followed, with much of it committed by adult women. Participants recounted being asked, in adolescence, to send nude photos and receiving persistent sexual demands, often from older women. In addition, participants reported uncertainty with gender role expectations, believing that they were supposed to enjoy sexual attention but in reality finding it disturbing and unpleasant. Practical implications, policy recommendations, and future directions are discussed.
Assessment of cerebrospinal fluid analysis and short‐term survival outcomes in South American camelids: A retrospective study of 54 cases (2005‐2021)
Authors: Bennett Samuel J. , Adkins Pamela R. F. , Schultz Loren G. , Walker Kelsey E. 
Published: September 2022

AbstractBackgroundCerebrospinal fluid (CSF) is commonly analyzed in South American camelids with suspected neurologic disease because of ease of collection and characteristic findings associated with certain diseases.ObjectivesTo assess CSF findings associated with short‐term survival or non‐survival in South American camelids in which neurologic disease was a differential diagnosis based on history and physical examination.AnimalsTwenty‐one llamas and 33 alpacas that underwent CSF analysis at the University of Missouri Veterinary Health Center.MethodsRetrospective study. Medical records of camelids that underwent CSF analysis between January 2005 and September 2021 were studied. Short‐term survival was defined as survival to discharge from the Veterinary Health Center. A Fisher's exact test was used to compare species, CSF results, and survival.ResultsOdds of survival were 3.9 times higher in camelids with a total nucleated cell count (TNCC) <3 cells/μL (P = .04). No significant association was found between survival and total protein concentration (TPC;P = .15) or percentage of eosinophils (P = 1.0). No significant correlation was found between species and increased TNCC (P = .63), TPC (P = .55), or percentage of eosinophils (P = .30). Among camelids diagnosed withParalephostrongylus tenuisinfestation, odds of survival were 4.95 times higher in alpacas (P = .05).ConclusionsCerebrospinal fluid TNCC ≥3 cells/μL is associated with decreased odds of short‐term survival in South American camelids.
Romanticism and the everyday
Authors: Ostas Magdalena 
Published: September 2022

AbstractThis essay surveys recent scholarship in the study of Romanticism that takes an interest in the concept of the everyday. Why does the everyday have pull and import for scholars of British literature and culture in the late eighteenth and early nineteenth century? This essay argues that the power of the everyday as a concept extends far beyond its expected meaning or its simple association with day‐to‐day or conventional life. First, this essay shows that in Romantic scholarship the everyday, instead, often indicates a mode of understanding, a framework for reading the past and present—what I call the everyday as historiographic method. Second, this essay shows that in strains of literary criticism that take the adjacent concept of the “ordinary” as a persistent concern, the everyday is not a method but an aspiration or an achievement. This lineage of thinking about the everyday, I argue, in the field inspired by the writings of the later Wittgenstein loosely described as “ordinary language philosophy” remains largely peripheral in the field of literary studies today. This essay thus aims to highlight new contributions in Romantic scholarship at the crossroads of literary and philosophical thinking.
First insight into oral microbiome diversity in Papua New Guineans reveals a specific regional signature
Authors: Pedro Nicole , Brucato Nicolas , Cavadas Bruno , Lisant Valentine , Camacho Rui , Kinipi Christopher , Leavesley Matthew , Pereira Luisa , Ricaut François‐Xavier 
Published: September 2022

AbstractThe oral microbiota is a highly complex and diversified part of the human microbiome. Being located at the interface between the human body and the exterior environment, this microbiota can deepen our understanding of the environmental impacts on the global status of human health. This research topic has been well addressed in Westernized populations, but these populations only represent a fraction of human diversity. Papua New Guinea hosts very diverse environments and one of the most unique human biological diversities worldwide. In this study we performed the first known characterization of the oral microbiome in 85 Papua New Guinean individuals living in different environments, using a qualitative and quantitative approach. We found a significant geographical structure of the Papua New Guineans oral microbiome, especially in the groups most isolated from urban spaces. In comparison to other global populations, two bacterial genera related to iron absorption were significantly more abundant in Papua New Guineans and Aboriginal Australians, which suggests a shared oral microbiome signature. Further studies will be needed to confirm and explore this possible regional‐specific oral microbiome profile.
The dynamic response to hypo‐osmotic stress reveals distinct stages of freshwater acclimation by a euryhaline diatom
Authors: Downey Kala M. , Judy Kathryn J. , Pinseel Eveline , Alverson Andrew J. , Lewis Jeffrey A. 
Published: September 2022

AbstractThe salinity gradient separating marine and freshwater environments is a major ecological divide, and the mechanisms by which most organisms adapt to new salinity environments are poorly understood. Diatoms are a lineage of ancestrally marine microalgae that have repeatedly colonized and diversified in freshwaters. Cyclotella cryptica is a euryhaline diatom found in salinities ranging from fully freshwater to fully marine, thus providing a powerful system for understanding the genomic mechanisms for mitigating and acclimating to low salinity. To understand how diatoms mitigate acute hypo‐osmotic stress, we abruptly shifted C. cryptica from seawater to freshwater and performed transcriptional profiling during the first 10 h. Freshwater shock dramatically remodelled the transcriptome, with ~50% of the genome differentially expressed in at least one time point. The peak response occurred within 1 h, with strong repression of genes involved in cell growth and osmolyte production, and strong induction of specific stress defence genes. Transcripts largely returned to baseline levels within 4–10 h, with growth resuming shortly thereafter, suggesting that gene expression dynamics may be useful for predicting acclimation. Moreover, comparison to a transcriptomics study of C. cryptica following months‐long acclimation to freshwater revealed little overlap between the genes and processes differentially expressed in cells exposed to acute stress versus fully acclimated conditions. Altogether, this study highlights the power of time‐resolved transcriptomics to reveal fundamental insights into how cells dynamically respond to an acute environmental shift and provides new insights into how diatoms mitigate natural salinity fluctuations and have successfully diversified across freshwater habitats worldwide.