bluuebunny/crossref_metadata_2025_split huggingface dataset:
With or without a purpose? Judges’ appraisal of offenders or their behaviour in six sentencing remarks
Authors: Dai Xin 
Published: August 2022

Abstract
This study examines judges’ language use in sentencing remarks in the Crown Courts of England and Wales. Six sentencing remarks were selected from all those available on the UK judiciary website (by October 2016). The cases selected for closer analysis are as similar to each other as possible, so as to ensure that the differences in the discursive features of the sentencing remarks largely reflect the differences in judges’ sentencing practices. It is found that judges selectively use an appraisal strategy – using moralised purposes to invoke judgements of offenders or their behaviour – across the six sentencing remarks. Judges’ use (or non-use) of the appraisal strategy is found to be correlating with their sentencing decisions: i.e., judges opt for the appraisal strategy when their sentencing decisions are below or further above the starting point, but not when the decisions are just a few years above the starting point. The finding reveals that the statutory starting point exercises a binding effect on the judges’ sentencing practices despite the judges having the discretion to disregard the starting point. Such a finding not only provides an insight into the judges’ sentencing practices, but also demonstrates that appraisal analysis is an effective means to get access to sentencing, which seemed so inaccessible to academic research.
Numerical investigation of a variable stator vane with nonuniform partial radial gaps in an annular compressor cascade
Authors: Zhang Yimin , Chen Shaowen , Liu Yueqi , Wang Songtao 
Published: August 2022

Abstract
A variable stator vane (VSV) with nonuniform partial radial gaps is numerically investigated in an annular compressor cascade. Five adjusting angles (α = −5.5°, −5°, 0°, 5° and 10°) are chosen to simulate different working conditions. The VSV is adjusted in negative direction means that the stagger angle increases and the VSV is more closed. Since the VSV is installed in an annular cascade, the heights of the partial gaps are nonuniform and reaches 3.8% of the span. Results show that as the VSV is adjusted negatively, the total pressure loss rises by 20.3% and a huge area of corner separation appears. The outflow angle is also more distorted along radial direction. Comparisons with a fixed-configuration stator show that although the VSV would cause higher loss, it indeed plays an important role in adjusting the outflow angle.
Complex dynamical behaviour of predator–prey model with harvesting and multiple delays
Authors: Pal Amit K. , Mondal Ashok 
Published: August 2022

Abstract
In this work, we investigate a predator–prey model with Crowley–Martin functional response and constant harvesting. The model is extended by incorporating two constant time delays, where the first delay(τ
1) is for density dependent feedback mechanism in the logistic growth of the prey and the second one is for gestation delay(τ
2) of the predator population. The dynamical behaviours such as positivity, boundedness, extinction criteria and existence, stability and bifurcations of the equilibria of the non-delay model are qualitatively discussed. The existence of periodic solutions via Hopf-bifurcation with respect to absence of delay, single delay and both delays are established. Finally, numerical simulations have been carried out to confirm our numerical results.
Lineage Analysis ofCxcr4-Expressing Cells in the Developing Midbrain Suggests That Progressive Competence Restriction in Dopaminergic Progenitor Cells Contributes to the Establishment of Dopaminergic Neuronal Diversity
Authors: Petese Alessandro , Fries Franca L. , Broske Bianca , Stumm Ralf , Blaess Sandra 
Published: August 2022

AbstractMidbrain dopaminergic (mDA) neurons are generated from a ventral midbrain progenitor zone over a time span of several days [embryonic day 10.0 (E10.0) to E14.5 in mouse]. Within this neurogenic period, a progressively changing fate potential of mDA progenitors could contribute to the generation of diverse mDA neuronal subpopulations. To test this idea, we combined inducible genetic fate mapping and intersectional labeling approaches to trace the lineage of cells expressing the chemokine receptor CXCR4. TheCxcr4transcript is expressed in mDA progenitors and precursors, but not in differentiated mDA neurons.Cxcr4-expressing mDA progenitors/precursors labeled at E11.5 develop into a broad range of mDA neurons, whereas labeling of theCxcr4lineage at later time points (E12.5–E15.5) results in an increasingly restricted contribution to mDA neurons proceeding from lateral to medial in the substantia nigra and from dorsal to ventral in the ventral tegmental area. In parallel, the innervation of dopaminergic projection targets by mDA neurons derived fromCxcr4-expressing cells is becoming more restricted: the late-generated mDA neurons innervate only the medial–rostral regions in the dorsal striatum and only the medial shell in the nucleus accumbens. Our results suggest that mDA progenitor cells become increasingly restricted in their cell fate potential over time.
Coordination between Eye Movement and Whisking in Head-Fixed Mice Navigating a Plus Maze
Authors: Bergmann Ronny , Sehara Keisuke , Dominiak Sina E. , Kremkow Jens , Larkum Matthew E. , Sachdev Robert N. S. 
Published: August 2022

AbstractNavigation through complex environments requires motor planning, motor preparation, and the coordination between multiple sensory–motor modalities. For example, the stepping motion when we walk is coordinated with motion of the torso, arms, head, and eyes. In rodents, movement of the animal through the environment is coordinated with whisking. Even head-fixed mice navigating a plus maze position their whiskers asymmetrically with the bilateral asymmetry signifying the upcoming turn direction. Here we report that, in addition to moving their whiskers, on every trial mice also move their eyes conjugately in the direction of the upcoming turn. Not only do mice move their eyes, but they coordinate saccadic eye movement with the asymmetric positioning of the whiskers. Our analysis shows that asymmetric positioning of whiskers predicted the turn direction that mice will make at an earlier stage than eye movement. Consistent with these results, our observations also revealed that whisker asymmetry increases before saccadic eye movement. Importantly, this work shows that when rodents plan for active behavior, their motor plans can involve both eye and whisker movement. We conclude that, when mice are engaged in and moving through complex real-world environments, their behavioral state can be read out in the movement of both their whiskers and eyes.
Machine-learning potentials for crystal defects
Authors: Freitas Rodrigo , Cao Yifan 
Published: August 2022

AbstractDecades of advancements in strategies for the calculation of atomic interactions have culminated in a class of methods known as machine-learning interatomic potentials (MLIAPs). MLIAPs dramatically widen the spectrum of materials systems that can be simulated with high physical fidelity, including their microstructural evolution and kinetics. This framework, in conjunction with cross-scale simulations and in silico microscopy, is poised to bring a paradigm shift to the field of atomistic simulations of materials. In this prospective article we summarize recent progress in the application of MLIAPs to crystal defects.Graphical abstract
Alternative Imaginations: Confronting and Challenging the Persistent Centrism in Social Media-Society Research
Authors: Lim Merlyna 
Published: August 2022

This article attempts to intervene the current trend in social media research that, to a certain degree, reflects the centrality of technology. Beyond the broad trend of technocentrism, I identify and outline four other major oversights or challenges in researching the social media/society relationship, namely online data centrism, moment centrism, novelty centrism, and success centrism. Stemmed from these four types of centrism, I offer an alternative imagination, namely a set of alternative pathways in social media research that value histories and historical context, interdisciplinarity, longue durée, and complexity. By revealing these oversights, this article aims to contribute to our collective attempt to interrogate the relationship between social media and society (and technology/society) critically. This alternative imagination might help animate, reveal, and make transparent various societal dynamics that otherwise would be invisible and, thus, might contribute to a better, deeper, and more comprehensive understanding of the technology/society relationship.
Development of methods of operative determination of parameters of repeated hydrate formation in layer systems of gas hydrate deposits
Authors: Pedchenko Nazar 
Published: August 2022

The object of research is the methods of laboratory setting of the parameters of hydrate formation of well production and the design features of the equipment for its implementation. Methane hydrate is becoming a promising topic for a new energy resource. At the same time, hydrostatic formation is one of the most problematic areas in ensuring the transport of well products, and this primarily concerns the production of gas hydrate deposits. An analysis of the thermobaric parameters of the well production of gas hydrate deposits shows that when they are moved by technological lines, they are close to hydrate equilibrium, but due to the intensity of the process, the system does not have time to reach it. In addition, reservoir system water has a memory of hydrate structures, or a certain amount of gas hydrate solid phase is also present in the flow water. In this regard, a set of laboratory studies was carried out to assess the nature of the behavior of this type of systems during the re-crystallization of gas hydrate and its dissociation. Based on the results of the research, a method for the operational laboratory setting of the parameters of repeated hydrate formation in reservoir systems of gas hydrate deposits was developed. It provides for setting the parameters of mass crystallization of gas hydrate by visual fixation of the moment of appearance of the solid phase at the interfacial contact «liquid – gas». The design features of the laboratory facility for its implementation have also been developed and substantiated. The technique makes it possible to reduce the duration of the study of one sample by almost an order of magnitude (from several days to 8–10 hours). In addition to the information on the equilibrium parameters of hydrostatic formation, provided by traditional methods of laboratory research, an additional characteristic of the behavior of reservoir systems in non-equilibrium conditions has been obtained, which will help to quickly assess the risks of technogenic hydrate formation. The developed technique is important for systems that, at least, have a memory of hydrate structures. However, the preliminary transfer of a part of the water of the test sample through the gas hydrate form allows estimating the parameters of hydrate formation of any reservoir system.
Application of varieties of technogenic raw materials in cement technology
Authors: Dorogan Nataliia , Varshavets Petro , Chernyak Lev , Shnyruk Oleg 
Published: August 2022

The possibility of manufacturing a mineral binder using large-tonnage waste from other industries has been studied. The object of the research are mixtures for the manufacture of cement clinker based on systems of chalk – clay – scope of paper production and chalk – clay – husks of rice processing. At the same time, urgent tasks of developing the raw material base for cement production and resource conservation were solved. The development of new initial mixtures was carried out taking into account the peculiarities of the chemical and mineralogical composition of varieties of technogenic raw materials. According to the chemical composition, rice alkali is characterized by a content of 15.6 wt. % SiO2 with a large quantitative ratio of SiO2:Al2O3=65.2 and a small amount of alkaline earth and alkaline oxides. Scop differs from alkali in a large amount of CaO (25.8 wt. %), a lower content of SiO2 at a quantitative ratio of SiO2:Al2O3=1.3. In this case, there are quantitative ratios of oxides CaO:SiO2=2.5, CaO:Al2O3=3.3, CaO:SiO2:Al2O3=3.3:1.4:1, which determine the probable phase transformations during firing. The main rock-forming mineral in rice husks is amorphous silica; Scope is marked by the presence of crystalline phases of calcite, quartz, and kaolinite. The analysis of the possible content of the studied wastes and the determination of the compositions of the raw mixtures were carried out using the computer program «Clinker». Analysis of computer calculations and experiments indicates the possibility of reducing by 11–16 wt. % consumption of natural raw materials in the composition of mixtures for the manufacture of clinker in comparison with the known production composition. According to X-ray phase analysis, the features of the development of crystalline phases during the firing of mixtures using varieties of technogenic raw materials at a maximum temperature of 1400 ºС were established. Based on the data of technological testing, the differences in indicators of binding properties were determined - the setting time of cement when used in the composition of raw mixtures of rice husk and paper scope.
Assessment of the impact of traffic conditions on the availability of transport services of the city bus route
Authors: Vdovychenko Volodymyr , Ivanov Igor , Pidlubnyi Serhii 
Published: August 2022

The object of research is the influence of the conditions for the implementation of technological trip operations in the implementation of the priority movement of urban passenger transport on the bus route on the level of accessibility of the transport service. On the basis of the developed contour of information communication, a typical procedure for establishing the parameter for assessing the availability of a transport service, depending on the time indicators of traffic on the route, is singled out. As a controlled parameter that determines the conditions for increasing the availability of a transport service, the trip time and the range of deviations in the arrival of buses to the stopping point are singled out. Implemented on the basis of simulation modeling, the procedure for establishing the correspondence between the time parameters of the departure of buses from the stopping point and the formation of demand made it possible to establish patterns of changes in the level of accessibility of the transport service depending on the traffic conditions on the route.
In the course of field observations along route No. 115e «Gagarin avenue metro station – Nesterov street» (Kharkiv, Ukraine) it was found that the introduction of free traffic conditions that meet the conditions of the priority of urban passenger transport can reduce the duration of the trip by 5 min and reduce the range of deviation of the arrival of buses to the stopping point by 4 min. On the basis of experimental studies, it was found that by reducing the duration of the trip from 32 min up to 27 min it is possible to increase the value of the transport service accessibility indicator by 20.5 %. When organizing traffic according to a schedule, it is possible to increase the indicator of the availability of transport services up to 0.679 (by 6.8 %). The introduction of priority traffic on route No. 115e allows reducing the trip time to 22–27 min, which will positively affect the indicator of the availability of transport services (increase to 0.803 in traffic without a schedule and up to 0.880 in compliance with the traffic schedule). Reducing the range of bus arrival deviations in the range from –1 min up to +2 min allows increasing the level of accessibility of transport services under normal conditions from 6.8 % to 13.3 %, and with the introduction of priority traffic – from 15.4 % to 18.3 %.
Modification of scaled equation of state to determine the pressure in the CO2 critical region
Authors: Vorobiova Hanna 
Published: August 2022

The object of the research is carbon dioxide and its pressure distribution depending on the range of temperature and density in the region of the critical point. One of the most problematic areas of methods for finding thermodynamic parameters of a real gas is insufficient accuracy in calculations in the places of occurrence and rapid development of fluctuation phenomena, which are inherent in phase transitions of the first and second terms. For a more detailed and accurate description of the nature of the thermodynamic parameters in the region of the critical point, scaling and crossover equations of state were developed. Such equations, due to the presence of regular and scaling parts, allow describing the thermodynamic parameters of a real gas not only directly near the critical point, but also at some distance from it, maintaining a small error relative to experimental data. The article proposes an equation of state, which contains a scaling part described according to the rules of statistical physics, and a regular part in the form of a classical cubic equation of state. The equation is used to calculate the pressure of carbon dioxide in the region around the critical point from 300 K to 305 K. The article proposes a correlation equation for the scaling correction of the regular part (Redlich-Kwong-Aungier model) of the crossover equation of state, which is related to the scaling part the equation of state is a crossover function. The obtained results for the pressure in the critical region showed good agreement with the baseline data. The error relative to the experimental data is halved compared to the original model of the Redlich-Kwong-Aungier equation. The obtained results ensure the applicability of the proposed method in the temperature range from 300 K to 305 K. Due to the simplicity of the form of the regular equation of state and the small number of empirical coefficients for the large-scale equation of state, the obtained method can be used for practical problems of computational hydrodynamics without spending a lot of computing time.
KLC3 Regulates Ciliary Trafficking and Cyst Progression in CILK1 Deficiency–Related Polycystic Kidney Disease
Authors: Rah Gyuyeong , Cha Hwayeon , Kim Joohee , Song Jieun , Kim Hyunho , Oh Yun Kyu , Ahn Curie , Kang Minyong , Kim Jongmin , Yoo Kyung Hyun , Kim Min Jung , Ko Hyuk Wan , Ko Je Yeong , Park Jong Hoon 
Published: August 2022

Significance Statement
Mutations in ciliogenesis-associated kinase 1 (CILK1) cause ciliopathies. However, the pathogenesis of the ciliary defect in the CILK1-deficient kidney remains unknown. We found that CILK1 deficiency in a mouse model leads to polycystic kidney disease (PKD) with abnormal ciliary trafficking and that kinesin light chain–3 (KLC3), a novel ciliary regulator, interacts with CILK1. Furthermore, KLC3 localizes at cilia bases, where it promotes ciliary trafficking of the IFT-EGFR complex, which contributes to cyst progression. KLC3 knockdown restored abnormal ciliary trafficking and cyst progression caused by CILK1 deficiency. Identifying KLC3 as a ciliary regulator involved in cystogenesis provides insights into the pathogenesis of CILK1 deficiency–related PKD.

Background
Ciliogenesis-associated kinase 1 (CILK1) is a ciliary gene that localizes in primary cilia and regulates ciliary transport. Mutations in CILK1 cause various ciliopathies. However, the pathogenesis of CILK1-deficient kidney disease is unknown.

Methods
To examine whether CILK1 deficiency causes PKD accompanied by abnormal cilia, we generated mice with deletion of Cilk1 in cells of the renal collecting duct. A yeast two-hybrid system and coimmunoprecipitation (co-IP) were used to identify a novel regulator, kinesin light chain–3 (KLC3), of ciliary trafficking and cyst progression in the Cilk1-deficient model. Immunocytochemistry and co-IP were used to examine the effect of KLC3 on ciliary trafficking of the IFT-B complex and EGFR. We evaluated the effects of these genes on ciliary trafficking and cyst progression by modulating CILK1 and KLC3 expression levels.

Results
CILK1 deficiency leads to PKD accompanied by abnormal ciliary trafficking. KLC3 interacts with CILK1 at cilia bases and is increased in cyst-lining cells of CILK1-deficient mice. KLC3 overexpression promotes ciliary recruitment of IFT-B and EGFR in the CILK1 deficiency condition, which contributes to the ciliary defect in cystogenesis. Reduction in KLC3 rescued the ciliary defects and inhibited cyst progression caused by CILK1 deficiency.

Conclusions
Our findings suggest that CILK1 deficiency in renal collecting ducts leads to PKD and promotes ciliary trafficking via increased KLC3.
Extérioriser l’intime ou la crise permanente du théâtre. "La Maison d’os" de Roland Dubillard : « monodrame polyphonique » ?
Authors: Kaczmarek Tomasz 
Published: August 2022

La Maison d’os de Rolland Dubillard se situe explicitement dans le sillage de la « dramaturgie rhapsodique » qui remet en cause les contraintes de la forme canonique que Szondi a définie comme le « drame absolu ». N’étant pas fondée sur un grand conflit, la construction de l’œuvre ne respecte pas la dynamique de l’action (au demeurant, inexistante), tout en se concentrant sur la confrontation d’un protagoniste avec lui-même. Ainsi, l’intersubjectif, sur lequel est bâtie une pièce traditionnelle, cède la place à l’intrasubjectif qui se manifeste, en l’occurrence, au travers d’un monodrame polyphonique. De fait, en étudiant le texte de Dubillard, on constate que l’auteur renonce à l’ancien paradigme pour mieux explorer l’intériorité du personnage principal. Celui-ci mène une vie de solitaire, entouré par ses nombreux valets qui semblent les pâles reflets de son âme déchirée. S’affranchissant du monologue, l’écrivain conçoit de cette manière un monodrame à plusieurs voix. Ce procédé ne signifie pourtant pas la crise du genre, il constitue une des solutions permettant son évolution.
Flange Sizing Recommendations for Frequent Breast Pump Use
Authors: Fortin Higgins Ashton 
Published: August 2022

IntroductionGuidance to assist in establishing a precise breast flange fit can be found in previously published nipple diameter research, case observations of pumping subjects, and in manufacturer’s flange-fit recommendations.MethodsThe nipple diameters of 11 exclusively pumping individuals were measured with either a standard ruler, ruler with a circular diameter, or coins, and variations were observed that required reconsideration of the flange size.ConclusionsGLactation professionals in practice need to consider variations in nipple diameter and systematic ways to measure nipples should be explored with exclusively or near-exclusively pumping individuals.