bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nerve conduction studies in the early diagnosis of amyotrophic lateral sclerosis and the importance of split-hand phenomenon
Authors: SÜMBÜL Orhan , AKSOY Dürdane , KURT Semiha Gülsüm , ÇEVİK Betül 
Published: August 2022

Aim: The heterogeneity of the Amyotrophic Lateral Sclerosis (ALS) clinical phenotypes leads to difficulties in early diagnosis. The ‘split hand’ sign is defined as the thenar muscles that are more prominently affected by hypothenar. In this study, the results of the initial nerve conduction study of the patients were compared with those of the controls in order to increase the findings supporting early diagnosis.
Material and Method: Seventy-five patients who were diagnosed with ALS in our clinic were included in the study. The initial ENMG findings of the patients were compared with those of 70 healthy controls: Distal motor latency (DML), the compound muscle action potential (CMAP) amplitude, velocity in the motor conduction of median, ulnar, peroneal and tibial nerves; distal latency, amplitude, velocity in sensorial conduction were evaluated. Ulnar/median DML and ulnar/median CMAP amplitude ratios were examined.
Results: In ALS group, DMLs of the median, ulnar, peroneal, and tibial nerves were significantly longer, and CMAP amplitudes were significantly smaller than those of the controls. The sensory conductions of the median, ulnar, and sural nerves were not statistically different between the groups. The ulnar/median DML ratio of the patients was lower than the ratio of controls (0.73/0.80;p=0.003); while the ulnar/median CMAP amplitude ratio was greater (1.40/1.11; p=0.002).
Conclusion: Prolonged DML and reduced amplitudes were observed in the motor nerve conduction of ALS patients in the early period. The results of the present study also support the presence of split-hand phenomenon even in early period of limb-onset ALS (both upper and lower). These findings suggest that nerve conduction studies and electrophysiologically detected split-hand sign are important clues for the early diagnosis of ALS in case of heterogeneous clinical phenotype.
Evaluation of the Patients Developing Severe Pleural Effusion After Isolated Coronary Artery Bypass Operation
Authors: AKBAYRAK Hakan , TEKÜMİT Hayrettin 
Published: August 2022

Objective: In this study, we aim to determine the causal relationship between isolated coronary bypass surgery development of severe pleural effusion in the early postoperative period.
Methods: In this study, 7862 isolated coronary artery bypass surgery cases conducted in our hospital between February 2001 and July 2013 were analyzed retrospectively.
Results: Early-severe pleural effusion developed in 175 (2.2%) patients included in the study. The mean age of these cases was 66.3±9.5 (55-76). 149 (85.1%) of the cases were operated under elective conditions and 26 (14.9%) of them were operated under emergency conditions. The mean cardiopulmonary bypass time of the cases was 70±28 (40-100) minutes. Left internal thoracic artery (LITA) and saphenous vein graft (SVG) were used together in 161 (92%) cases. Of the cases, 126 (72%) had shortness of breath, 115 (65.7%) dry cough, 28 (16%) productive cough, 50 (28.6%) tachypnea, 22 (12.5%) chest pain. Early severe pleural effusion developed in the left hemithorax in 154 (88%) of the cases. LITA+SVG was used in 148 (84.6%) of these cases, and only SVG was used in 6 (3.4%) cases. Early severe pleural effusion developed in the right hemithorax in 14 (8%) of the cases. LITA+SVG was used in 10 (5.7%) of these cases, and only SVG was used in 4 (2.3%) cases. The cases with bilateral early severe pleural effusion were 7 (4%). LITA+SVG was used in 3 (1.7%) of these cases, and only SVG was used in 4 (2.3%) cases.
Conclusion: It is known that coronary artery bypass surgery causes deterioration of postoperative pulmonary function. One of the most common complications of coronary artery bypass surgery is pleural effusion. It is known that this postoperative picture is associated with increased hospital stay and high postoperative morbidity. It is important to determine preoperative risks in terms of postoperative patient management and morbidity assessment.
Does treatment with somatostatin analogs differ in the uptake of normal target organs and malignant lesions on 68Ga-DOTATATE PET/CT imaging?
Authors: YILMAZ Farise , ÖNNER Hasan , KARA GEDİK Gonca , ŞAHİN Özlem , ÇELİK Ahmet Volkan , EROL Çağlagül 
Published: August 2022

Abstract
Objective:
Somatostatin analogs (SSA) are used in treating low-grade neuroendocrine tumors, mainly because of their antiproliferative effect. 68Ga tetraazacyclododecantetraacetic acid-DPhe1-Tyr3-octreotate (DOTATATE) PET/CT as somatostatin receptor imaging has been widely used in recent years. However, there are conflicting publications in the literature, although there are guidelines for discontinuing the use of SSA before imaging. This study aims to investigate the effect of SSAs on Somatostatin receptor imaging.
Material and Method: We retrospectively analyzed 253 patients who underwent 68Ga-DOTATATE PET/CT imaging between 2018 and 2022. Among these patients, those with low grades (Grade 1 and Grade 2) using SSA were included in the study. SUVmax (maximum standard uptake volume) of normal target organs, primary tumors, and metastases with the highest SUVmax in each organ were compared before and after SSA treatment.
Results: 28 patients (16 females; 12 males, age [mean±SD], 54.82±14.27, range 18-78) with low-grade (Grade 1 and 2) NET and 68Ga-DOTATATE PET/CT imaging with SSA therapy were included in the study. Although SUVmax was decreased in the values measured after SSA application in the liver and spleen, it was not statistically significant (p>0.05). There was no significant difference between SUVmax values in primary tumors and metastatic lesions in the liver, bone, lung, or lymph nodes before and after SSA application (P> 0.05).
Conclusion: In conclusion, these drugs do not need to be discontinued before 68Ga-DOTATATE PET/CT imaging for treatment follow-up in neuroendocrine tumor patients using somatostatin analogs. In addition, these drugs may help report interpretation by increasing the intensity of metastatic lesions in the liver and spleen.
ANALISIS KONTRIBUSI EKSPOR KOPI TERHADAP PDB SEKTOR PERKEBUNAN DI INDONESIA
Authors: Suwali Suwali , Hendri Putranto Afif , Bintang Panunggul Victor , Putriana Nuramanah Kinding Dwi , Noviani Faizah 
Published: August 2022

Keberhasilan suatu negara dalam mengembangkan perekonomiannya ditandai dengan nilai dan tingkat pertumbuhan produk domestik bruto (PDB). Ekspor dapat mendorong pertumbuhan PDB suatu negara. Perkebunan merupakan salah satu sub sektor pertanian yang memiliki pengaruh penting terhadap perkembangan Indonesia menjadi negara berkembang seperti sekarang ini. Banyaknya perkebunan kopi menjadikan Indonesia sebagai salah satu negara penghasil kopi terbesar di dunia setelah Brazil, Vietnam dan Kolombia. Ada beberapa kopi lokal yang dikenal di seluruh dunia antara lain kopi Gayo, kopi Toraja, kopi Lampung, dan kopi Aceh. Peningkatan ekspor Indonesia selalu ditempuh dengan berbagai strategi, termasuk strategi ekspansi ekspor khususnya produk non migas untuk mendorong pertumbuhan ekonomi.
Penelitian ini bertujuan : (1) mengetahui bagaimana perkembangan ekspor komoditi kopi di Indonesia periode 2011 sampai 2020. (2) mengetahui kontribusi ekspor kopi terhadap PDB sektor perkebunan di Indonesia periode 2011 sampai 2020. Penelitian ini menggunakan metode studi kasus dengan pendekatan kuantitatif. Data yang digunakan adalah data sekunder periode 2011 sampai dengan 2020 yaitu volume produksi kopi periode 2011-2020, GDP sektor perkebunan priode 2011-2020, volume dan nilai ekspor kopi Indonesia periode 2011-2020, volume dan nilai ekspor kakao, kelapa sawit dan karet periode 2011-2020. Analisis yang digunakan adalah analisis statistik deskriptif dan analisis kontribusi ekspor kopi terhadap PDB sektor perkebunan. Hasil penelitian menjelaskan bahwa : (1) Perkembangan ekspor kopi Indonesia bersifat flutuatif dengan tren cenderung menurun. Rata-rata ekspor kopi Indonesia sebesar 693.136 ton per tahun selama periode 2011 sampai 2020. (2) Ekspor kopi memberikan kontribusi positif terhadap peningkatan PDB sektor perkebunan di Indonesia, dibandingkan dengan ekspor komoditi perkebunan lainya seperti kelapa sawit, kakao dan karet. Rata-rata kontribusi ekspor kopi terhadap PDB sektor perkebunan di Indonesia sebesar 3,13 persen per tahun selama periode 2011 sampai 2020.
ПРИМЕНЕНИЕ ПАНТОВ МАРАЛА ДЛЯ КУПИРОВАНИЯ ХРОНИЧЕСКОГО ОСТЕОМИЕЛИТА: ОЦЕНКА РЕГЕНЕРАТИВНЫХ СПОСОБНОСТЕЙ
Authors: Золотухин Владимир Олегович , Андреев А.А. , Глухов А. А. 
Published: August 2022

Аннотация: Остеомиелит – наиболее сложный вариант развития воспаления, которое диагностируется в 3-24% после открытых переломов и в 1-7% после остеосинтеза.
Цель: изучение эффективности применения пантов марала и амикацина в купировании хронического травматического остеомиелита.
Материалы и методы. Исследование проведено на самцах крыс линии Wistar с массой 300±20 граммов на базе НИИ ЭБМ ВГМУ им Н.Н.Бурденко. Все экспериментальные животные были разделены на 5 групп. В 1-й контрольной группе лечение не проводилось. В остальных группах выполняли 2-х этапную гидрохирургическую санацию (ГХС). Костную полость в 1-й опытной группе заполняли измельченными пантами марала; во 2-й опытной группе – амикацином в дозировке 15 мг/кг и гидроксиапатитом кальция; в 3-й опытной группе – пантами марала и амикацина в дозировке 1:2 и гидроксиапатитом кальция.
Результаты: В 3-й опытной группе показатели нормализовались к 90-м суткам. На рентгене к указанным суткам костный дефект полностью закрыт, свищевые ходы и секвестры отсутствуют, прослеживается четкий рисунок и выраженные границы кортикального слоя.
Заключение. Оптимальным методом купирования хронического остеомиелита является одномоментное применение антибиотика амикацина и пантов марала в массовом соотношении 2/1 (с учетом максимальной дозы амикацина 15 мг/кг.) По данным рентгенологического метода исследования при использовании данного метода происходит полное восстановление архитектоники костной ткани к 90-м суткам исследования.
Cloud learning technology: an attempt to define
Authors: Markova O. M. 
Published: August 2022

Objectives of the study: to give a definition of cloud learning technology as a computer-oriented component of educational technology.Research objectives: 1) to form definition of cloud learning technology; 2) to clarify the relations of cloud learning technology, educational technologies, ICT, cloud technologies and ICT of learning.Object of study: cloud technology in education.Research subject: cloud learning technology.Methods: source analysis, definition synthesis.Research results: a definition of cloud learning technology was given; the relations of cloud learning technology, educational technologies, ICT, cloud technologies and ICT of learning was given.Conclusions and recommendations:1) the content of cloud learning technology is the intersection of sets of concepts related to cloud technology and ICT-based learning;2) further development of research involves determining the historical and pedagogical conditions of emerging and development of cloud learning technology.
The cloud technologies for mathematics teachers training
Authors: Popel M. V. 
Published: August 2022

This article is devoted to modern approaches to interpretations of "the cloud technology", the types of cloud computing application for teachers training are discussed. A comparative analysis of Web-SCM SAGE and The Sagemath Cloud is made.Aim: to do a theoretical analysis of pedagogical application of Web-SCM SAGE and The Sagemath Cloud.Objectives: 1) to make an analysis of contemporary approaches to the interpretation of the concept of "of cloud technology"; 2) to consider Web-SCM in terms of the cloud-based environment; 3) to compare Web-SCM SAGE and The Sagemath Cloud.Object of study: the learning process of university students with the support of cloud technologies.Purpose of the study: to reveal the features of The Sagemath Cloud use in high school.Methods: the study of the domestic scientific pedagogical publications on the problems of implementation and use of advanced cloud technology, and Web-SCM including Web-SAGE and The Sagemath Cloud.Results: advantages and disadvantages of The Sagemath Cloud application in comparison to the Web-SCM SAGE are revealed.Conclusions considered various interpretations regarding the concept of "of cloud technology", comparison of Web-SCM SAGE and The Sagemath Cloud as learning tools.
Kepemimpinan Teladan HOS Tjokroaminoto di Sarekat Islam Tahun 1914-1923
Authors: Anggoro Deni Prasetyo 
Published: August 2022

Di dalam sebuah organisasi non profit, motivasi anggota untuk bergabung, mayoritas bukanlah karena materi. Sehingga cara untuk menggerakan anggota organiasai non profit tentu akan berbeda dengan menggerakan bawahan pada organisasi profit. Kepemimpinan teladan merupakan salah satu cara untuk menggerakan anggota organisasi non profit. HOS Tjokroaminoto dikenal sebagai salah satu pemimpin besar di Indonesia pada masa pra kemerdekaan. Salah satu kekuatan kepemimpinan yang dimiliki HOS Tjokroaminoto dalam memimpin adalah keteladanan yang dimiliki. Dengan kepemimpinan teladan, HOS Tjokroaminoto mampu menjadi orang yang paling berpengaruh di organisasi Sarekat Islam. Di bawah kepemimpinannya pula, Sarekan Islam menjadi salah satu organisasi besar di Hindia Belanda. Artikel ini akan membahas bagaimana kepemimpinan teladan yang dilakukan oleh HOS Tjokroaminoto saat memimpin organisasi Sarekat Islam. Penelitian ini merupakan penelitian kualitatif pustaka. Hasil dari penelitian ini bentuk kepemimpinan teladan yang dilakukan oleh HOS Tjokroaminoto yaitu: pertama, HOS Tjokroaminoto memimpin dengan memberikan teladan kesederhanaan dalam kehidupan pribadi maupun sebagai pemimpin organisasi. Kedua, HOS Tjokroaminoto memimpin dengan visi yang kuat yaitu kesejahteraan dan persatuan umat Islam, pembentukan negara Indonesia yang merdeka dan mandiri dengan jalan non konfontatif dengan kerajaan Belanda, mandiri dalam mengelola alam. Ketiga, HOS Tjokroaminoto memimpin dengan inovasi strategi seperti perjuangan kemerdekaan melalui jalan evolusi di saat banyak pejuang yang memilih jalan revolusi, membuat keputusan bergabung voolskraad di saat banyak pejuang menolak tawaran Belanda untuk bergabung dengan voolskraad, membentuk CSI sebagai cara untuk menyiasati aturan dari Belanda mengenai organisasi, dan membangun sekolah desa berbasis sekolah tani. Keempat, HOS Tjokroaminoto memimpin dengan memberikan kepercayaan besar kepada bawahannya seperti mengangkat Gunawan menjadi wakil ketua SI 1914-1916, mengangkat Abdul Muis menjadi wakil ketua SI 1916-1921, dan memilih Agus Salim untuk masuk ke dalam voolskraad menggantikan dirinya. Kelima, HOS Tjokroaminoto membangkit semangat anggota melalui pidato-pidato yang menggelegar.
Kata kunci: HOS Tjokroaminoto, kepemimpinan, Sarekat Islam, kepemimpinan teladan, motivasi
Detection Of Treatment Adherence, Disease Control and Its Predictors in Asthma Patients by Rural Community Level Health Workers
Authors: Mukhopadhyay Prianka , Chakraborty Sumanta , Sarkar Manisha 
Published: August 2022

Background: Despite the availability of effective therapy, disease control in Asthma remains suboptimal with high morbidity.
Objectives: To assess treatment adherence, asthma control and its influencing factors.
Methodology: A prospective, observational study was conducted among 152 adult asthma patients reporting consecutively to a BPHC for twelve months. Patients were followed up by trained healthcare workers to assess their treatment adherence and disease control using a predesigned, pretested and validated questionnaire.
Results: Mean age was 49.6 years (SD = +14.0), males reported more cases (73.7%), addiction to tobacco was high (48.7%). 40.8% patients had high treatment adherence. Only 37.5% patients reported good asthma control of which 68.4% showed high adherence. The mean Asthma Control Test (ACT) score was 18.75 ± 4.8 SD. Increasing age (aOR=0.96, 95% CI= 0.93-0.99), tobacco smoking (aOR=2.90, 95% CI=1.20-6.99), dust allergy (aOR= 7.92, CI =3.15-19.91) and low treatment adherence (aOR=5.33, 95% CI=2.22-12.82) were found to be significant predictors of poor disease control.
Conclusions: Non adherence to treatment and poor disease control were high among rural asthma patients. Patient education for tobacco cessation and treatment compliance along with periodic monitoring undertaken by trained health workers can be an effective strategy to reduce disease burden in the community.
Microleakage of two different posterior composites and a high-viscosity glass-ionomer cement: An in vitro study
Authors: Çelenk Sema , Ataş Osman , Ayna Buket , Günay Ayşe 
Published: August 2022

Aim: Using AutoCAD, we examined the microleakage of permanent molars in Class I restorations using a conventional posterior composite resin, a bulk-fill composite resin, and a high-viscosity glass-ionomer cement (HVGIC).
Methodology: In total, 33 extracted noncarious third molars were used. Class I cavities were prepared. The teeth were randomly divided into three groups of 11 teeth each, as follows: Group A (Filtek Z550), Group B (Filtek Bulk-Fill Posterior Restorative), and Group C (EQUIA Fil). All specimens were stored for 24 h at 37 °C in distilled water. The teeth were thermocycled 1,000 times between 5 ± 2°C and 55 ± 2°C prior to immersion in 0.5% basic fuchsin for 24 h. Two mesiodistal cuts of each tooth were photographed under a stereomicroscope equipped with a digital camera. The dye-infiltrated surface area was measured.
Results: Statistical evaluations were performed by one-way analysis of variance [ANOVA]. One-way ANOVA showed no significant difference between the three groups in microleakage (P = 0.07). However, the lowest microleakage ratio was seen in Group C (EQUIA Fil). Similar results were obtained with all tested materials, but the lowest microleakage rate was obtained with EQUIA Fil (Group C).
Conclusion: In this study, the tested materials were not completely successful in eliminating microleakage, although the lowest microleakage rate was obtained with EQUIA Fil.

How to cite this article:
Çelenk S, Ataş O, Ayna B, Günay A. Microleakage of two different posterior composites and a high-viscosity glass-ionomer cement: An in vitro study. Int Dent Res 2022;12(1):34-8. https://doi.org/10.5577/intdentres.2022.vol12.no1.6

Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.
An Attempt to Understand the Biology of Gender and Gender Dysphoria: A Christian Approach
Authors: Jelsma Tony 
Published: August 2022

The recent rise in the number of transgender individuals has perplexed many. A study of possible biological origins of gender dysphoria presents a complex picture. In some cases, prenatal hormonal imbalance may cause early-onset and persistent gender dysphoria. In contrast, late-onset cases are associated with a high incidence of comorbidities such as trauma, depression, and autism. In such cases, social isolation and an impaired body image may make individuals susceptible to social media suggestions of gender dysphoria. Moreover, affirmative counseling without addressing underlying comorbidities can strengthen this misperception, further moving these individuals along a trajectory toward transition. Care must be taken when considering early transition, given the fact that childhood gender dysphoria frequently desists. One must balance sparing a child from the distressing sexual changes of puberty with beginning transition in someone who might otherwise have desisted. Recent studies of perception suggest that it is a top-down predictive, "best guess" process. Although these "guesses" are continuously modified by sensory experience, they can persist; they might also apply to some cases of gender dysphoria. While some people have managed to detransition back to their natal gender, we should not assume that this is possible with everyone. As Christians, we need to examine each case individually, removing the stigma and supporting them through this distressing condition.
Fire Properties of Hybrid Composites
Authors: Mohammed Ibrahim 
Published: August 2022

Thermal conductivity of a components subjected to high temperature is an important property to be considered in a materials to be used in automobile and aerospace fire designated zones; likewise, it is availability, cost, stiffness, resistant to corrosion, and its strength. The main aim of the study is to investigate the fire behavioural properties of fibre metal laminates (FML) composite of a metal, synthetic, natural and polymer matrix. The composites were fabricated in a mould using hand lay-up method and allow to cured before test.. The fire property test was carried out using the standard properties test equipment as ISO 2685 propane burner thermocouples and heat flux meter. The result of the properties test shows a remarkable increase in the properties of only natural fibre metal laminate composites, with a slight decrease in the properties of pure synthetic fibre metal laminates. Flax composite has a high percentage of 21.43% of thermal conductivity and withstand the flame temperature for 15 minutes using an ISO 2685 standard while kenaf composite fail at 10 minutes 30 seconds, Conclusively, the composites can be used as the component in fire designated zones of automotive, aerospace and other machines.