bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Cognitive-Behavioural Approach to Targeting Sensation-Based and Intrusion-Based Misinterpretations in Health Anxiety: A Single-Case Experimental Study
Authors: Lau-Zhu A. , Brummer L. 
Published: November 2022

AbstractHealth anxiety (HA) is common in psychiatric and medical settings. Cognitive models of HA highlight the role of misinterpreting physical sensations as dangerous. This report presents the case of a 31-year-old man and the use of a cognitive-behavioural approach to treat his HA which also considers the role of misinterpreting intrusions as abnormal, by drawing on theoretical accounts of obsessive-compulsive disorder (OCD). A single-case experimental design demonstrated reliable improvements in symptom measures of HA and general distress. Distinguishing sensation-based versus intrusion-based appraisals in HA has implications for interventions in health settings and for refining cognitive theory.
The UK Seasonal Worker Visa
Authors: Mantouvalou Virginia 
Published: November 2022

AbstractThis article discusses the United Kingdom (UK) 2019 Seasonal Worker Visa, which was adopted to address labour shortages in horticulture. It explains the challenges faced by workers in agriculture more broadly, and the particular issues raised by seasonal visas. It argues that the UK scheme contains significant restrictions on workers’ rights. The article situates this scheme in a framework of ‘state-mediated structures of injustice’, namely instances where legal rules with an appearance of legitimacy create or increase vulnerability and are connected to widespread structures of exploitation. This theoretical framework focuses on the role and responsibility of the state for workers’ exploitation. The authorities have political responsibility to change these rules, and may also have legal responsibility to do so under human rights law.
Has the seasonal workers directive missed its target? Evidence from Italy during the pandemic
Authors: Passalacqua Virginia 
Published: November 2022

AbstractIn 2014, the European Union adopted the Seasonal Workers Directive to achieve a twofold aim: meeting employers’ demand for flexible and cheap labour and enhancing protection for third-country national (TCN) workers. Especially Article 23, the equal treatment provision, triggered a cautious optimism among scholars and trade unions, which looked at the Directive as a source of increased protection for seasonal workers. However, trade unions also pointed out the limited reach of the Directive, criticising its lack of commitment and ambition. Over the years, and especially during the Covid pandemic, it became clear that the Seasonal Workers Directive did not represent a game-changer for TCN seasonal workers, whose increased protections remained true only on paper. This contribution draws on the case of Italy during the pandemic to understand the reasons for the Directive’s limited impact. The article critically examines the different political tensions underpinning the adoption of the Directive, to better understand why the Directive is not applied in practice and how it impacts the labour market and migrants’ social conditions.
The dynamics of the tip vortices shed by a tip-loaded propeller with winglets
Authors: Posa Antonio 
Published: November 2022

The tip vortices shed by two marine propellers are studied, relying on large-eddy simulation, using a cylindrical grid consisting of 5 billion points. A tip-loaded design, featuring winglets at the tips of its blades, is compared against a conventional one at the design advance coefficient and a model-scale Reynolds number equal to 432 000. The tip-loaded propeller achieves improved performance, but produces also more intense tip vortices. The propeller with winglets actually generates two vortices from the tip of each blade, originating at the edge of each winglet and at the junction between the winglets and the blades. They merge at a short distance downstream, within a diameter from the propeller plane. The helical vortices originating from this merging process experience a slower instability, in comparison with the tip vortices in the wake of the conventional propeller, persisting further downstream, due to the weaker shear with the wakes shed by the following blades. The results of the simulations highlight that splitting the single tip vortex of a conventional propeller into two smaller vortices by means of winglets does not imply necessarily the generation of weaker vortices and lower negative peaks of pressure at their core: the geometry of the winglets needs to be carefully optimized to achieve this target.
Anthropometric trajectory in the course of life and occurrence of sarcopenia in men and women: results from the ELSA-Brasil cohort
Authors: Santos Clarice Alves , Fraga-Maia Helena , Pitanga Francisco José Gondim , Almeida Maria da Conceição Chagas , Fonseca Maria de Jesus Mendes , Aquino Estela Mota Leão , Cardoso Letícia de Oliveira , Barreto Sandhi Maria , Duncan Bruce , Schmidt Maria Inês , Matos Sheila Maria Alvim 
Published: November 2022

AbstractThis study aimed to identify patterns of anthropometric trajectories throughout life and to analyse their association with the occurrence of sarcopenia in people from the Longitudinal Study of Adult Health (ELSA-Brasil). It is a cross-sectional study involving 9670 public servants, aged 38–79 years, who answered the call for new data collection and exams, conducted approximately 4 years after the study baseline (2012–2014). Data sequence analysis was used to identify patterns of anthropometric trajectory. A theoretical model was elaborated based on the directed acyclic graph (DAG) to select the variables of minimum adjustment in the analysis of the causal effect between trajectory and sarcopenia. Poisson regression with robust variance was adopted for data analysis. The patterns of change in the anthropometric trajectory were classified in stable weight (T1); change to normal weight (T2); change to excess weight (T3); weight fluctuation (T4) and change to low weight (T5). The prevalence of sarcopenia in men and women who changed the anthropometric path for the low weight was twice as large when compared to participants with a stable weight trajectory. A protective effect of the excess weight trajectory was observed for the occurrence of sarcopenia in them. The results pointed to the need for health policies that encourage the proper management of body components in order to prevent and control obesity, as well as to preserve the quantity and quality of skeletal muscle mass throughout life, especially in older adults.
Large-scale brain functional network abnormalities in social anxiety disorder
Authors: Zhang Xun , Yang Xun , Wu Baolin , Pan Nanfang , He Min , Wang Song , Kemp Graham J. , Gong Qiyong 
Published: November 2022

AbstractBackgroundAlthough aberrant brain regional responses are reported in social anxiety disorder (SAD), little is known about resting-state functional connectivity at the macroscale network level. This study aims to identify functional network abnormalities using a multivariate data-driven method in a relatively large and homogenous sample of SAD patients, and assess their potential diagnostic value.MethodsForty-six SAD patients and 52 demographically-matched healthy controls (HC) were recruited to undergo clinical evaluation and resting-state functional MRI scanning. We used group independent component analysis to characterize the functional architecture of brain resting-state networks (RSNs) and investigate between-group differences in intra-/inter-network functional network connectivity (FNC). Furtherly, we explored the associations of FNC abnormalities with clinical characteristics, and assessed their ability to discriminate SAD from HC using support vector machine analyses.ResultsSAD patients showed widespread intra-network FNC abnormalities in the default mode network, the subcortical network and the perceptual system (i.e. sensorimotor, auditory and visual networks), and large-scale inter-network FNC abnormalities among those high-order and primary RSNs. Some aberrant FNC signatures were correlated to disease severity and duration, suggesting pathophysiological relevance. Furthermore, intrinsic FNC anomalies allowed individual classification of SAD v. HC with significant accuracy, indicating potential diagnostic efficacy.ConclusionsSAD patients show distinct patterns of functional synchronization abnormalities both within and across large-scale RSNs, reflecting or causing a network imbalance of bottom-up response and top-down regulation in cognitive, emotional and sensory domains. Therefore, this could offer insights into the neurofunctional substrates of SAD.
Social risk factors for SARS-CoV-2 acquisition in university students: cross sectional survey
Authors: Blakey Eleanor , Reeve Lucy , Verlander Neville Q. , Edwards David , Wyllie David , Reacher Mark 
Published: November 2022

Abstract
The objectives of this study were to define risk factors for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in University of Cambridge (UoC) students during a period of increased incidence in October and November 2020. The study design was a survey.
Routine public health surveillance identified an increase in the numbers of UoC students with confirmed SARS-CoV-2 positivity in the 10 days after a national lockdown was announced in the UK on 5th November 2020. Cases were identified both through symptom-triggered testing and a universal asymptomatic testing programme. An online questionnaire was sent to all UoC students on 25 November to investigate risk factors for testing positive in the period after 30th October 2020. This asked about symptoms, SARS-CoV-2 test results, aspects of university life, and attendance at social events in the week prior to lockdown. Univariate and multivariable analyses were undertaken evaluating potential risk factors for SARS-CoV-2 positivity.
Among 3980 students responding to the questionnaire, 99 (2.5%) reported testing SARS-CoV-2 positive in the period studied; 28 (28%) were asymptomatic. We found strong independent associations with SARS-CoV-2 positivity and attendance at two social settings in the City of Cambridge (adjusted odds ratio favouring disease 13.0 (95% CI 6.2–26.9) and 14.2 (95% CI 2.9–70)), with weaker evidence of association with three further social settings. By contrast, we did not observe strong independent associations between disease risk and accommodation type or attendance at a range of activities associated with the university curriculum.
To conclude attendance at social settings can facilitate widespread SARS-CoV-2 transmission in university students. Constraint of transmission in higher education settings needs to emphasise risks outside university premises, as well as a COVID-safe environment within university premises.
The climate crisis is here: a primer and call to action for public health nutrition researchers and practitioners in high-income countries
Authors: Bell Brooke M 
Published: November 2022

AbstractDietary behaviours and the food systems in which they occur have a significant impact on climate change. The 2022 Intergovernmental Panel on Climate Change (IPCC) reports and other major climate reports have identified population-level dietary shifts towards balanced, sustainable healthy diets as an important mitigation (i.e. prevention) solution for climate change. Thus, public health nutrition researchers and practitioners have a crucial role to play in combatting the climate crisis. They have the content expertise, interdisciplinary training and technical skills needed to facilitate wide-scale dietary behaviour changes at multiple levels of influence and ultimately improve both human and planetary health. This commentary article: (i) summarises how dietary behaviours and food systems contribute to climate change, with a particular focus on high-income countries; (ii) reviews food-system-related climate change mitigation solutions most relevant to public health nutrition researchers and practitioners; and (iii) identifies key gaps in the literature and future research directions for the field.
Exploring primary healthcare practitioners’ experiences regarding the coronavirus disease 2019 (COVID-19) pandemic in KwaZulu-Natal, South Africa
Authors: Mchunu Gugu Gladness , Harris Orlando , Nxumalo Celenkosini Thembelenkosini 
Published: November 2022

AbstractBackground:The coronavirus disease 2019 (COVID-19) has spread rapidly around the world since the initial outbreak in Wuhan, China. With the emergence of the Omicron variant, South Africa is presently the epicentre of the COVID-19 pandemic in sub-Saharan Africa. Healthcare workers have been at the forefront of the pandemic in terms of screening, early detection and clinical management of suspected and confirmed COVID-19 cases. Since the beginning of the outbreak, little has been reported on how healthcare workers have experienced the COVID-19 pandemic in South Africa, particularly within a low-income, rural primary care context.Methods:The purpose of the present qualitative study design was to explore primary healthcare practitioners’ experiences regarding the COVID-19 pandemic at two selected primary healthcare facilities within a low-income rural context in KwaZulu-Natal, South Africa. Data were collected from a purposive sample of 15 participants, which consisted of nurses, physiotherapists, pharmacists, community caregivers, social workers and clinical associates. The participants were both men and women who were all above the age of 20. Data were collected through individual, in-depth face-to-face interviews using a semi-structured interview guide. Audio recordings were transcribed verbatim. Data were analysed manually by thematic analysis following Tech’s steps of data analysis.Results:Participants reported personal, occupational and community-related experiences related to the COVID-19 pandemic in South Africa. Personal experiences of COVID-19 yielded superordinate themes of psychological distress, self-stigma, disruption of the social norm, Epiphany and conflict of interest. Occupational experiences yielded superordinate themes of staff infections, COVID-19-related courtesy stigma, resource constraints and poor dissemination of information. Community-related experiences were related to struggles with societal issues, clinician-patient relations and COVID-19 mismanagement of patients.Conclusion:The findings of this study suggest that primary healthcare practitioners’ experiences around COVID-19 are attributed to the catastrophic effects of the COVID-19 pandemic with the multitude of psychosocial consequences forming the essence of these experiences. Ensuring availability of reliable sources of information regarding the pandemic as well as psychosocial support could be valuable in helping healthcare workers cope with living and working during the pandemic.
The UN75 Declaration, Our Common Agenda and the development of international law
Authors: Peyró Llopis Ana 
Published: November 2022

AbstractIn the declaration on the commemoration of the seventy-fifth anniversary of the United Nations, Member States requested that the Secretary-General provide recommendations to advance “Our Common Agenda” and to respond to current and future challenges. The Secretary-General issued a report entitled “Our Common Agenda” on 5 August 2021, which, among others, reinforces the role of the United Nations as a place of choice for the development of international law, also putting in context the role and specific prerogatives of the Secretary-General in the promotion of international law. The declaration and “Our Common Agenda” have also presented an opportunity to counter sentiments regarding a supposed general decline in respect for international law.
Two sides of the same coin? The association between suicide stigma and suicide normalisation
Authors: Oexle N. , Valacchi D. , Grübel P. , Becker T. , Rüsch N. 
Published: November 2022

Abstract

Aims
Evidence suggests that suicide stigma (i.e. negative attitudes towards persons affected by suicide/suicidality) and suicide normalisation (i.e. liberal attitudes towards suicide) are both associated with increased suicide risk. Despite conceptual similarities and potential interaction, suicide stigma and suicide normalisation have usually been investigated separately. We used cross-sectional data from a community sample to test the association between suicide stigma and suicide normalisation as well as to identify their respective determinants and consequences.

Methods
Participants were N = 3.269 adults recruited from an established online-panel using quotas to reflect the composition of the German general population with regard to age, gender, education and region. We collected information about suicide stigma, suicide normalisation, intentions to seek help for suicidality, current suicidality, suicide literacy, negative mood and socio-demographic variables. We used regression modelling to determine the association between suicide stigma and suicide normalisation as well as to identify their determinants and consequences.

Results
Suicide stigma and suicide normalisation were inversely associated so that higher suicide stigma scores were linked to lower suicide normalisation. More suicide stigma was associated with reduced intentions to seeking professional help, increased willingness to seek help from family and friends and lower odds to experience current suicidality, however the association between suicide stigma and intentions to seek professional help diminished after controlling for confounding variables. Increased suicide normalisation was linked to reduced intentions to seek help from professionals or family and friends, as well as higher odds to experience current suicidality, even after controlling for confounding variables.

Conclusions
Our findings suggest that interventions to reduce public suicide stigma are at risk to unintentionally increase suicide normalisation, which appears to be a key barrier to seeking help for suicidality. Future research should therefore identify strategies to improve attitudes towards persons affected by suicidality that avoid normalisation, i.e. do not convey the message of suicide as an acceptable solution for difficult life situations. One strategy with great potential to safely reduce public suicide sigma could be interventions that stimulate interpersonal contact with affected persons sharing their recovery story.
Greigite Formation Modulated by Turbidites and Bioturbation in Deep‐Sea Sediments Offshore Sumatra
Authors: Yang Tao , Dekkers Mark J. , Zhao Xixi , Petronotis Katerina E. , Chou Yu‐Min 
Published: November 2022

AbstractAuthigenic greigite may form at any time within a sediment during diagenesis. Its formation pathway, timing of formation, and geological preservation potential are key to resolving the fidelity of (paleo‐)magnetic signals in greigite‐bearing sediments. In the cored sequence of the International Ocean Discovery Program Expedition 362 (Sumatra Subduction Margin), multiple organic‐rich mudstone horizons have high magnetic susceptibilities. The high‐susceptibility horizons occur immediately below the most bioturbated intervals at the top of muddy turbidite beds. Combined mineral magnetic, microscopic, and chemical analyses on both thin sections and magnetic mineral extracts of sediments from a typical interval (∼1,103.80–1,108.80 m below seafloor) reveal the presence of coarse‐grained greigite aggregates (particles up to 50–75 μm in size). The greigite formed under nonsteady state conditions caused by the successive turbidites. Organic matter, iron (oxy)(hydr)oxides, Fe2+, and sulfides and/or sulfate were enriched in these intensively bioturbated horizons. This facilitated greigite formation and preservation within a closed diagenetic system created by the ensuing turbidite pulse, where pyritization was arrested due to insufficient sulfate supply relative to Fe (oxy)(hydr)oxide. This may represent a novel greigite formation pathway under conditions modulated by turbidites and bioturbation. Paleomagnetic analyses indicate that the early diagenetic greigite preserves primary (quasi‐)syn‐sedimentary magnetic records. The extremely high greigite content (0.06–1.30 wt% with an average of 0.50 wt% estimated from their saturation magnetization) implies that the bioturbated turbiditic deposits are an important sink for iron and sulfur. Mineral magnetic methods, thus, may offer a window to better understand the marine Fe–S–C cycle.
Derepression of the USP22-FASN axis by p53 loss under oxidative stress drives lipogenesis and tumorigenesis
Authors: Han Zelong , Liu Ming , Xie Yuxin , Zeng Kunlin , Zhan Ziling , Chen Yanwen , Wang Li , Chen Xiaoxia , Luo Yaxin , Zeng Yu , Zhan Hongchao , Lin Yingzhuo , Zhang Keqin , Zhu Xiaoxia , Liu Side , Luo Xiaobei , Zhou Aidong 
Published: November 2022

AbstractOverproduction of reactive oxygen species (ROS) and aberrant lipid metabolism are established hallmarks of cancer; however, the role of ROS in lipid synthesis during tumorigenesis is almost unknown. Herein, we show that ROS regulates lipid synthesis and thus controls colorectal tumorigenesis through a p53-dependent mechanism. In p53 wild-type colorectal cancer (CRC) cells, hydrogen peroxide (H2O2)-induced p53 expression represses the transcription of deubiquitinase USP22, which otherwise deubiquitinates and stabilizes Fatty Acid Synthase (FASN), and thus inhibits fatty acid synthesis. Whereas, in p53-deficient CRC cells, ROS-mediated inhibition of USP22 is relieved, leading to FASN stabilization, which thus promotes lipid synthesis and tumor growth. In human CRC specimens, USP22 expression is positively correlated with FASN expression. Our study demonstrates that ROS critically regulates lipid synthesis and tumorigenesis through the USP22-FASN axis in a p53-dependent manner, and targeting the USP22-FASN axis may represent a potential strategy for the treatment of colorectal cancer.
Scalable synthesis of ultrastable lead halide perovskite-zeolite composites via a chemical vapor method in air
Authors: Shi Tongyu , Chen Xi , Deng Yuhao , Huang Hao , Wang Jiahong , He Rui , Liu Yanliang , He Xingchen , Li Jia , Chu Paul K. , Yu Xue-Feng 
Published: November 2022

AbstractA novel chemical vapor method is developed to synthesize ultrastable lead halide perovskite-zeolite (ZSM-5) composites, in which CsPbX3 (X = Cl, Br, I) perovskite quantum dots (QDs) are grown in situ in the nanopores of the ZSM-5 substrate. The key chemical reaction between PbBr2 vapor and the Si–O network in ZSM-5 leads to collapse of the initial zeolite crystal structure, realizing effective confinement and encapsulation of CsPbBr3 QDs and boosting their stability under harsh conditions, including heat, water, polar solvents, and ultraviolet (UV) light. At the same time, the acquired encapsulation structure possesses the channels needed for halogen exchange to regulate the halide ratios of the CsPbX3-ZSM-5 composites. The synthesized CsPbX3-ZSM-5 composites exhibit tunable emission from 400 to 700 nm and narrow full-widths at half-maximum (FWHM). To demonstrate the commercial potential, CsPbX3-ZSM-5 composites synthesized on a large scale are applied in white light-emitting diodes (WLEDs) and multicolor-coded anti-counterfeiting inks.