bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conceptualization and validation of brand social capital construct by analyzing the role of social media capital
Authors: Zarei Azim , Taheri Ghazale , Ghazvini Hadi 
Published: July 2022

Purpose
Researchers, with the widespread acceptance of Web-based technologies by companies, have recently discovered a new type of social capital through these mass communication tools, but there is still limited knowledge about its formation. Therefore, this study specifically aims to conceptualize and validate brand social capital (BSC) by analyzing the role of the online brand community’s social media capital (OBCSC).

Design/methodology/approach
Research data was collected using a questionnaire with 39 closed-ended questions. Participants, among the 220 questionnaires distributed, only returned 140 acceptable questionnaires, indicating a response rate of 64%. The statistical population of the study included managers and employees of e-commerce companies active in social media in the field of B2C who introduce and sell their products and services on various types of social networking websites. This study performed data analysis using structural equation modeling with partial least squares.

Findings
The results showed that OBCSC has a positive and significant effect on the integration of brand knowledge, branding co-creation and sense of belonging to the brand community, and in addition, using the mediating role of these three variables, it also has a positive effect on BSC. This study rejects only hypothesis 8 among all the hypotheses formulated, which shows that the sense of belonging to the brand community has no significant effect on branding co-creation.

Originality/value
By conceptualizing a new phenomenon called BSC and how its conversion mechanism is, this research defines a specific and formulated path to better identify the results of the organizational use of social media. In addition, it significantly contributes to increasing managers’ understanding of the importance of online brand community activities in internalizing customer brand knowledge within the company and turning it into wealth.
Resporulation of Metarhizium anisopliae granules on soil and mortality of Tenebrio molitor: Implications for wireworm management in sweetpotato
Authors: Shah Sudhan , Ash Gavin J. , Wilson Bree A. L. 
Published: July 2022

AbstractIn Australia, sweetpotato (Ipomoea batatas L.) is vulnerable to root feeding insect pests such as wireworms (e.g., Agrypnus spp.). The number of registered insecticides to control these insect pests is limited and often pest pressure, for example by wireworms, is severe close to harvest, further limiting what insecticides can be applied. Incorporating biological control agents such as entomopathogenic fungi (e.g., Metarhizium anisopliae) into integrated pest management programmes may be feasible in sweetpotato. M. anisopliae has been shown to be effective in controlling more than 200 insects and it is able to reside and grow in the rhizosphere and rhizoplane, suggesting that M. anisopliae could be a promising candidate against soil insect pests. In the study presented here, M. anisopliae was formulated into calcium alginate granules fortified with nutrients. The resporulation of the fungal granules was tested on four different soil types in the laboratory. The biocontrol efficacy of the resulting fungal growth was also examined using larval mealworms, Tenebrio molitor as a model insect in the laboratory and the glasshouse. Our results indicated that sterilised soil favoured optimal fungal resporulation, although different soil types did not have a significant effect on fungal resporulation. The resulting fungal resporulation and growth on sterilised soil caused high mortality (up to 76%) of larval mealworms in the glasshouse, whereas the fungal granules applied to non‐sterile soil demonstrated poor resporulation that led to low mortality (13%) of larval mealworms. The result of this study indicates that the manipulation of microbial populations in field soil is required to enhance the fungal growth and potential insect control against wireworms in the field.
Chronic ethanol exposure induced anxiety‐like behaviour by altering gut microbiota and GABA system
Authors: Yao Hui , Zhang Dalin , Yu Hao , Shen Hui , Lan Xinze , Liu Hao , Chen Xiaohuan , Wu Xu , Zhang Guohua , Wang Xiaolong 
Published: July 2022

AbstractEthanol, also known as alcohol, is one of the most common drinks in the world. Chronic ethanol exposure has been reported to induce mental disorders. Ethanol also has a strong effect on the gut microbiota. The gut microbiota has been reported to affect the brain via multiple pathways, including changes in γ‐aminobutyric acid (GABA) system, and cause a variety of mental disorders. The GABA system in the cortex is associated with anxiety. However, the role of gut microbiota played in ethanol exposure‐induced changes in the GABA system and anxiety is still not clear. We established a 30‐day ethanol exposure mouse model and investigated the effects of microbiota using the antibiotic minocycline. Minocycline alleviated ethanol‐induced anxiety‐like behaviour, dysbiosis of microbiota, intestinal barrier disruption, increased serum endotoxin and interleukin (IL)‐6. Minocycline also attenuated ethanol‐induced apoptosis and decreased expression of glutamate decarboxylases (GADs) and GABRA1 in the prefrontal cortex. Our results indicated that gut microbiota plays an important role in ethanol‐induced anxiety‐like behaviour by altering the function of GABA system. In addition, causal mediation analysis showed that endotoxin and IL‐6 may mediate the connection between the gut microbiota and the expression of GABAA receptor in the prefrontal cortex.
Impaired social decision‐making in males with methamphetamine use disorder
Authors: Li Ming‐Hui , Zhang Mingming , Yuan Ti‐Fei , Rao Li‐Lin 
Published: July 2022

AbstractIndividuals with methamphetamine use disorder (MUD) commonly exhibit socially problematic behaviours. Investigating the prosocial decision‐making of individuals with MUD could enable a better understanding of their impaired social functioning and help improve their social relationships. We conducted two studies to examine the performance of individuals with MUD and healthy controls on a modified dictator game. In Study 1, 55 male individuals with MUD and 34 healthy male participants made a series of choices between two pairs of monetary prizes for themselves and for others. In Study 2, 62 male individuals with MUD and 31 healthy male participants made the same choices as in Study 1 after a brief exposure to methamphetamine‐related pictures. In both studies, we consistently found a context dependency of decreased prosociality in individuals with MUD. That is, individuals with MUD made fewer prosocial choices than healthy individuals in disadvantageous contexts (but not advantageous contexts). The results of the computational model suggested that the lower prosociality of individuals with MUD in disadvantageous contexts could be attributed to the lower weight placed on others' benefits. Moreover, when exposed to methamphetamine‐related pictures, individuals with MUD showed less caution and slower encoding/motor speed than healthy individuals, and individuals with MUD with a longer history of methamphetamine use tended to respond less cautiously. Our findings provide evidence that in disadvantageous contexts, individuals with MUD show reduced prosociality and less consideration of others' benefits. Identifying the origin of the alterations in prosocial decision‐making has implications for diagnosis and treatment.
Characterization of telomere length in Agerolese cattle breed, correlating blood and milk samples
Authors: Iannuzzi Alessandra , Albarella Sara , Parma Pietro , Galdiero Giacomo , D'Anza Emanuele , Pistucci Ramona , Peretti Vincenzo , Ciotola Francesca 
Published: July 2022

AbstractStudies into telomere length in cattle are relatively recent and have focused mainly on the Holstein Friesian cattle breed, making it arduous to evaluate the correlation with ageing due to the early age of culling in this breed. Telomere length provides information about the productive lifespan and the quality of farm management, complying with the ‘One Health’ approach. This study evaluated telomere length in Agerolese cattle, an autochthonous dairy breed characterized by a long productive lifespan (13 years). Multiplex quantitative PCR estimated telomere length in DNA extracted from blood and milk matrices. Interestingly, the results showed longer telomeres in Agerolese (compared to the Holstein Friesian cattle control group), with a negative correlation between telomere length and increasing age and a synchronous trend between blood and milk samples, with a positive correlation between them.
Plasma E‐selectin and kallistatin as predictive markers of histologic chorioamnionitis in women with preterm premature rupture of membranes
Authors: Cho Iseop , Lee Kyong‐No , Joo Eunwook , Kim Yu Mi , Kim Tae Eun , Park Kyo Hoon 
Published: July 2022

AbstractProblemWe aimed to assess the predictive potential of 12 plasma biomarkers to predict acute histologic chorioamnionitis (HCA) in women with preterm premature rupture of membranes (PPROM) and to develop multi‐biomarker panels based on these biomarkers in combination with widely used conventional laboratory markers.Method of studyThis was a retrospective cohort study involving 81 singleton pregnant women (24–34 weeks of gestation) who delivered within 96 h of blood sampling. White blood cell (WBC) count, differential counts, and C‐reactive protein (CRP) levels were measured at admission. The levels of DKK‐3, Fas, haptoglobin, IGFBP‐2, kallistatin, MIP‐1α, MMP‐2, MMP‐8, pentraxin 3, progranulin, E‐selectin, and P‐selectin were evaluated by ELISA using stored plasma samples. The primary outcome measure was acute HCA.ResultsMultivariate analyses showed that low plasma E‐selectin and kallistatin levels were independently associated with HCA occurrence after adjusting for gestational age. Using a stepwise regression analysis, a multi‐biomarker panel comprising plasma E‐selectin, serum CRP, and WBC was developed, which provided a good prediction of acute HCA in women with PPROM (area under the curve [AUC], 0.899), with a significantly higher AUC than that of any single variable included in the panel (P < 0.05). The plasma levels of DKK‐3, Fas, haptoglobin, IGFBP‐2, MIP‐1α, MMP‐2, MMP‐8, pentraxin 3, and P‐selectin were not significantly associated with HCA occurrence.ConclusionsThis study identified E‐selectin and kallistatin as potential plasma biomarkers associated with acute HCA in women with PPROM. Their combined analysis with serum CRP and WBC counts significantly improved acute HCA diagnosis.
Review article: exclude or expose? The paradox of conceptually opposite treatments for irritable bowel syndrome
Authors: Biesiekierski Jessica R. , Manning Lauren P. , Murray Helen Burton , Vlaeyen Johan W. S. , Ljótsson Brjánn , Van Oudenhove Lukas 
Published: July 2022

SummaryBackgroundIrritable bowel syndrome (IBS) is a heterogeneous disorder of gut‐brain interaction (DGBI) maintained by interacting biological, psychological, and social processes. Interestingly, there are two contrasting yet evidence‐based treatment approaches for reducing IBS symptoms: exclusion diets such as those low in fermentable oligo‐, di‐, monosaccharides and polyols (FODMAPs) and exposure‐based cognitive‐behavioural therapy (CBT). Exclusion diets recommend patients avoid foods thought to be symptom‐inducing, whereas exposure‐based CBT encourages patients to expose themselves to foods.AimsTo address the paradox of conceptually opposite exclusion diets and exposure‐based CBT for IBS.MethodsIn this conceptual review, we describe the rationale, practical implementation, evidence base and strengths and weaknesses of each treatment. We conducted up‐to‐date literature search concerning the low FODMAP diet and CBT, and performed a secondary analysis of a previously conducted trial to illustrate a key point in our review.ResultsThe low FODMAP diet has demonstrated efficacy, but problems with adherence, nutritional compromise, and heightened gastrointestinal‐specific anxiety raise caution. Exposure‐based CBT has demonstrated efficacy with substantial evidence for gastrointestinal‐specific anxiety as a key mechanism of action. Mediation analysis also showed that increased FODMAP intake mediated decreased symptom severity in exposure‐based CBT. However, there is minimal evidence supporting which treatment “works best for whom” and how these approaches could be best integrated.ConclusionsEven though exclusion diets and exposure‐based CBT are conceptually opposite, they each have proven efficacy. Clinicians should familiarise themselves with both treatments. Further research is needed on predictors, mechanisms and moderators of treatment outcomes.
Best practice—Is natural revegetation sufficient to achieve mitigation goals in road construction?
Authors: Mehlhoop Anne Catriona , Skrindo Astrid Brekke , Evju Marianne , Hagen Dagmar 
Published: July 2022

AbstractAimsThe area influenced by road construction is large, and measures to re‐establish vegetation in disturbed areas are routinely carried out to reduce impacts on biodiversity. However, goals of mitigation measures are often unclear, and the effects on biodiversity of mitigation measures is rarely monitored. We assessed the effects of different revegetation treatments (natural revegetation, seeding, planting) on vegetation development along highways, and on wildlife crossings of different age.LocationHighways in southeast Norway.MethodsWe collected data on vascular plant species, vegetation cover and height, soil grain size and organic matter content, and compared the species composition, richness, and diversity of the restored sites with reference plots in the adjacent target vegetation (mature forest).ResultsOur results show a significantly higher richness and diversity in restored plots compared to reference plots, and an increased similarity of species composition over time. Species composition was most similar to reference plots in naturally revegetated plots and seeding seemed to reduce both species and functional trait composition similarity.ConclusionsIt is unrealistic that the defined target vegetation will develop on restored sites. Defining a realistic and achievable target vegetation for each road construction project in relation to land use, adjacent vegetation type and successional stage, as e.g., forest edge instead of forest, would be useful. While this may require more effort for management it will translate to higher mitigation success.
Estimation of adherence to medication treatment in presence of censoring
Authors: Pasquier Jérôme , Schneider Marie P. , Locatelli Isabella 
Published: July 2022

AimsThe purpose of this study is to provide a theoretical framework for the analysis of medication adherence based on longitudinal data from electronic medication monitors and to suggest methods for unbiased estimation of the effect of time and covariates on adherence.MethodsAfter defining the statistical summaries involved in adherence analyses and the assumptions necessary for their estimation, we address the issue of bias encountered when adherence is estimated on censored data. We suggest 2 unbiased methods to estimate adherence: (i) indirect combining implementation and persistence; and (ii) based on weights, allowing estimation of the effect of time and covariates on adherence via generalized estimating equations models.ResultsWe applied the proposed methods to investigate the effect of sex on adherence in a sample of 43 oncology patients followed 1 year. Implementation was higher for men than for women at baseline (98.8 vs. 97.5%, odds ratio [OR] 2.08, 95% confidence interval [CI]: 1.00–4.35), whereas the relationship was reversed at 1 year (94.5 vs. 96.4%, OR 0.65, 95%CI: 0.28–1.52). Adherence declined faster in men, with year‐end values of 46.3% for men and 92.2% for women (OR 0.07, 95%CI: 0.02–0.26).ConclusionEstimation of adherence is a complex statistical issue with longitudinal and duration data, possibly censored, interleaving. This study provides a theoretical framework and suggests methods for unbiased estimation of adherence as a function of time and covariates. This allows the effect of an intervention to be estimated in clinical trials, and helps healthcare providers reframe adherence programmes to address covariates such as sex.
More elaborate processing of own‐race faces and less elaborate processing of other‐race faces contribute to the other‐race effect in face memory
Authors: Herzmann Grit , Ogle Olivia , Curran Tim 
Published: July 2022

AbstractResearch suggests that own‐race faces are naturally memorized in a more elaborate (e.g., many features of a face or the whole face) way, whereas other‐race faces are memorized in a less elaborate (e.g., only selected features of the face) manner. Here, we tested if instructions for judgements about the whole face and a single facial feature modulated the other‐race effect in face memory. White participants performed whole‐face and single‐feature tasks while memorizing White and Black faces for later recognition. Encoding instructions had a stronger impact on own‐race than other‐race faces. Whole‐face instructions increased the other‐race effect, whereas single‐feature instructions decreased it. Own‐race faces in the whole‐face task demonstrated event‐related potential (ERP) patterns of memory encoding comparable to previously observed natural memory encoding, suggesting naturally more elaborate encoding of own‐race faces. ERPs of memory encoding for other‐race faces were similar between task conditions and comparable to previously observed natural encoding patterns, suggesting naturally less elaborate encoding. No impact of the encoding tasks was found on ERPs related to memory retrieval, which may be an artefact of a perceptual task that does not enhance semantic details in memory. The current results indicate that some contributions to the other‐race effect are more elaborate (more detailed) memory encoding for own‐race faces and less elaborate (less detailed) memory encoding for other‐race faces. This study also provides evidence for more malleability of own‐race than other‐race faces through task instructions, consistent with assumptions of perceptual learning theories of the other‐race effect.
MicroRNA‐210‐mediated mtROS confer hypoxia‐induced suppression of STOCs in ovine uterine arteries
Authors: Hu Xiang‐Qun , Song Rui , Dasgupta Chiranjib , Romero Monica , Juarez Rucha , Hanson Jenna , Blood Arlin B. , Wilson Sean M. , Zhang Lubo 
Published: July 2022

Background and PurposeHypoxia during pregnancy is associated with increased uterine vascular resistance and elevated blood pressure both in women and female sheep. A previous study demonstrated a causal role of microRNA‐210 (miR‐210) in gestational hypoxia‐induced suppression of Ca2+ sparks/spontaneous transient outward currents (STOCs) in ovine uterine arteries, but the underlying mechanisms remain undetermined. We tested the hypothesis that miR‐210 perturbs mitochondrial metabolism and increases mitochondrial reactive oxygen species (mtROS) that confer hypoxia‐induced suppression of STOCs in uterine arteries.Experimental ApproachResistance‐sized uterine arteries were isolated from near‐term pregnant sheep and were treated ex vivo in normoxia and hypoxia (10.5% O2) for 48 h.Key ResultsHypoxia increased mtROS and suppressed mitochondrial respiration in uterine arteries, which were also produced by miR‐210 mimic to normoxic arteries and blocked by antagomir miR‐210‐LNA in hypoxic arteries. Hypoxia or miR‐210 mimic inhibited Ca2+ sparks/STOCs and increased uterine arterial myogenic tone, which were inhibited by the mitochondria‐targeted antioxidant MitoQ. Hypoxia and miR‐210 down‐regulated iron–sulfur cluster scaffold protein (ISCU) in uterine arteries and knockdown of ISCU via siRNAs suppressed mitochondrial respiration, increased mtROS, and inhibited STOCs. In addition, blockade of mitochondrial electron transport chain with antimycin and rotenone inhibited large‐conductance Ca2+‐activated K+ channels, decreased STOCs and increased uterine arterial myogenic tone.Conclusion and ImplicationsThis study demonstrates a novel mechanistic role for the miR‐210‐ISCU‐mtROS axis in inhibiting Ca2+ sparks/STOCs in the maladaptation of uterine arteries and provides new insights into the understanding of mitochondrial perturbations in the pathogenesis of pregnancy complications resulted from hypoxia.
Lichen planus-like keratosis: what do we know about it?
Authors: Pogorzelska-Antkowiak Anna 
Published: July 2022

Abstract
Lichen planus-like keratosis is a common, benign pigmented skin lesion. It should be carefully diagnosed using modern diagnostic tools, such as dermoscopy and confocal microscopy, to avoid misdiagnosis as melanoma or other malignant pigmented lesions.
Patient choice in colorectal cancer treatment – A systematic review and narrative synthesis of attribute‐based stated preference studies
Authors: Kowal Mikolaj , Douglas Francesca , Jayne David , Meads David 
Published: July 2022

AbstractAimThe global burden of colorectal cancer (CRC) is set to increase by 60% by 2030. An aging population and increasing treatment complexity add difficulties for patients and clinicians in CRC management. Patient preferences can be investigated using attribute‐based stated preference (AbSP) techniques to explore trade‐offs between different treatments. These techniques include discrete‐choice experiments (DCEs), conjoint analysis and time‐trade off (TTO) methods. This systematic review with a narrative synthesis aimed to determine the use and design of AbSP studies in CRC treatment and to identify patient choice themes.MethodsThe searches were performed using MEDLINE, Embase, PsycInfo and Cochrane Library in March 2021. All manuscripts featuring the use of AbSP techniques in CRC treatment were included. Data synthesis was performed using a narrative approach.ResultsThe search strategy returned 271 articles. Eighteen AbSP studies were included featuring 1890 patients and 296 clinicians. AbSP techniques compromised DCE (38.9%, n = 7), TTO (38.9%, n = 7) and conjoint analysis (22.2%, n = 4). Eleven studies (61.1%) involved piloting of tasks and the average task completion rate was 75%. CRC treatments included chemotherapy (33%, n = 6), combined treatments (33%, n = 6), surgery (17%, n = 3), targeted therapy (11%, n = 2) and radiotherapy (6%, n = 1). The most examined domain was physical health, investigated with 49 (59.8%) attributes.ConclusionsLife expectancy was the main attribute in chemotherapy treatment. With surgery, patients were willing to trade life‐expectancy to avoid adverse outcomes or a permanent stoma. Communication skills, treatment cost, and clinicians' views were important attributes for patients in cancer services. Further research in the elderly population, and other quality of life domains, are needed to deliver patient‐centred CRC care.
Subjective equivalence scales in Eastern versus Western European countries
Authors: Mysíková Martina , Želinský Tomáš , Garner Thesia I. , Fialová Kamila 
Published: July 2022

AbstractWe show that economies of scale estimated individually for each EU country differ from the officially adopted OECD‐modified scale; the differences across the countries further confirm the prevailing East‐West disparity. Using the minimum income question in the 2019 EU‐Statistics on Income and Living Conditions survey, we demonstrate that applying the estimated country‐specific subjective equivalence scales, instead of the uniform OECD‐modified scale, results in up to a 6 pp change in the at‐risk‐of‐poverty rate. If inadequate equivalence scales are used, the equivalised income fails to inform the statistics of income poverty and prevents national social policies from being correctly targeted.