bluuebunny/crossref_metadata_2025_split huggingface dataset:
Significance of Nerve Plane for Inferior Mesenteric Plexus Preservation in Laparoscopic Rectal Cancer Surgery
Authors: Li Kai , Zeng Junjie , Pang Pengcheng , Cheng Hua , He Xiaobo , Cao Fengyu , Luo Qiang , Tong Shilun , Zheng Yongbin 
Published: April 2022

BackgroundStation 253 node dissection with high ligation of the inferior mesenteric artery (IMA) is difficult to perform without damage to the surrounding autonomic nerve plexuses. This study aimed to investigate the significance of the nerve plane for inferior mesenteric plexus (IMP) preservation in laparoscopic rectal cancer surgery.MethodsA total of 56 consecutive rectal patients underwent laparoscopic en bloc station 253 node dissection with high ligation of the IMA. Station 253 nodes were divided into the extra- and intra-nerve plane station 253 nodes for further H&amp;E staining and immunohistochemical analysis. Based on IMP nerve plane-based evidence and histopathological results, a novel nerve-sparing technique, IMP nerve plane orientation, was proposed and performed on 68 rectal cancer patients. Urinary and sexual functions in all patients were evaluated at 6 months postoperatively.ResultsLymph node metastasis was not found, but abundant nerve bundles containing gangliocytes were observed in extra-nerve plane station 253 nodes. The nerve plane was identified intraoperatively and then confirmed by both postoperative gross specimen evaluation and histopathological analysis. The novel nerve-sparing technique (IMP nerve plane orientation) was successfully performed with no postoperative complications, and the operated patients had improved postoperative urinary and sexual functions.ConclusionThe nerve plane is helpful for IMP preservation and station 253 node dissection. This novel nerve-sparing technique of nerve plane orientation is technically feasible and safe, which could result in faster recovery of urinary and sexual functions.
Prognostic and Clinical Significance of COX-2 Overexpression in Laryngeal Cancer: A Meta-Analysis
Authors: Du Jingwei , Feng Jun , Luo Deyan , Peng Lijuan 
Published: April 2022

ObjectiveSeveral studies were conducted to explore the clinical significance of cyclooxygenase-2 (COX-2) overexpression in laryngeal cancer. However, the associations between COX-2 overexpression and clinicopathological characteristics of laryngeal cancer patients remained unclear. Here, we performed a meta-analysis to eva-TY -40luate the role of COX-2 overexpression in the risk, clinical progression, and progno\sis of laryngeal cancer.MethodsThe eligible literature was obtained from PubMed, Embase, Web of Science, and China National Knowledge Infrastructure (CNKI) databases. Odds ratio (OR), risk ratio (RR), and 95% confidence interval (CI) were calculated to assess the strength of the associations, and I2 statistics were used to evaluate heterogeneity among studies. Publication bias was detected with Begg’s test and Egger’s test.ResultsA total of 47 eligible articles were included for the meta-analysis after screening. COX-2 expression levels in the laryngeal cancer patients were significantly higher than those in the normal controls (OR = 11.62, 95% CI: 6.96–19.40, P &lt; 0.05). The pooled results also showed that there were significant correlations between COX-2 overexpression and clinicopathological characteristics (tumor stage, OR = 3.26, 95% CI: 2.13–4.98, P &lt; 0.05; lymph node metastasis, in Asians, OR = 2.35, 95% CI: 1.53–3.60, P &lt; 0.05; recurrence, OR = 10.71, 95% CI: 3.54–32.38, P &lt; 0.05; T stage, in Asians, OR = 2.52, 95% CI: 1.66–3.83, P &lt; 0.05). In addition, significant correlations between COX-2 overexpression and overall survival of laryngeal cancer were found both in Asians and in Caucasians (total, HR = 1.73, 95% CI: 1.23–2.24, P &lt; 0.05; survival in Asians, HR = 2.59, 95% CI: 1.27–3.92, P &lt; 0.05; survival in Caucasians, HR = 1.59, 95% CI: 1.03–2.14, P &lt; 0.05).ConclusionsThe meta-analysis results suggested that COX-2 overexpression was significantly associated with the increased risk, worse clinicopathological progression, and poorer prognosis of laryngeal cancer.
Machine Learning Models for Classifying High- and Low-Grade Gliomas: A Systematic Review and Quality of Reporting Analysis
Authors: Bahar Ryan C. , Merkaj Sara , Cassinelli Petersen Gabriel I. , Tillmanns Niklas , Subramanian Harry , Brim Waverly Rose , Zeevi Tal , Staib Lawrence , Kazarian Eve , Lin MingDe , Bousabarah Khaled , Huttner Anita J. , Pala Andrej , Payabvash Seyedmehdi , Ivanidze Jana , Cui Jin , Malhotra Ajay , Aboian Mariam S. 
Published: April 2022

ObjectivesTo systematically review, assess the reporting quality of, and discuss improvement opportunities for studies describing machine learning (ML) models for glioma grade prediction.MethodsThis study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy (PRISMA-DTA) statement. A systematic search was performed in September 2020, and repeated in January 2021, on four databases: Embase, Medline, CENTRAL, and Web of Science Core Collection. Publications were screened in Covidence, and reporting quality was measured against the Transparent Reporting of a multivariable prediction model for Individual Prognosis Or Diagnosis (TRIPOD) Statement. Descriptive statistics were calculated using GraphPad Prism 9.ResultsThe search identified 11,727 candidate articles with 1,135 articles undergoing full text review and 85 included in analysis. 67 (79%) articles were published between 2018-2021. The mean prediction accuracy of the best performing model in each study was 0.89 ± 0.09. The most common algorithm for conventional machine learning studies was Support Vector Machine (mean accuracy: 0.90 ± 0.07) and for deep learning studies was Convolutional Neural Network (mean accuracy: 0.91 ± 0.10). Only one study used both a large training dataset (n&gt;200) and external validation (accuracy: 0.72) for their model. The mean adherence rate to TRIPOD was 44.5% ± 11.1%, with poor reporting adherence for model performance (0%), abstracts (0%), and titles (0%).ConclusionsThe application of ML to glioma grade prediction has grown substantially, with ML model studies reporting high predictive accuracies but lacking essential metrics and characteristics for assessing model performance. Several domains, including generalizability and reproducibility, warrant further attention to enable translation into clinical practice.Systematic Review RegistrationPROSPERO, identifier CRD42020209938.
Association Between Recombinant Growth Hormone Therapy and All-Cause Mortality and Cancer Risk in Childhood: Systematic Review and Meta-Analysis
Authors: He Mengyang , Deng Xiangling , Wang Xuan , Wan Yuxiang , Huang Jinchang , Zhang Zhixin , Niu Wenquan 
Published: April 2022

ObjectivesThe safety of recombinant human growth hormone (rhGH) treatment in childhood and the role of rhGH therapy in promoting tumorigenesis and progression have been the subject of debate for decades. We aimed to systematically assess the relationship between rhGH therapy in children and adolescents and clinical outcomes, including all-cause mortality, cancer mortality, cancer incidence, and risk of the second neoplasm.MethodsLiterature retrieval, study selection, and data extraction were completed independently and in duplicate. Effect-size estimates are expressed as standardized mortality ratios (SMRs), standardized incidence ratio (SIR), and relative risk (RR) with a 95% CI.ResultsData from 24 articles, involving 254,776 persons, were meta-analyzed. Overall analyses revealed the association of rhGH therapy was not statistically significant with all-cause mortality (SMR = 1.28; 95% CI: 0.58–2.84; P = 0.547; I2 = 99.2%; Tau2 = 2.154) and cancer mortality (SMR = 2.59; 95% CI: 0.55–12.09; P = 0.228; I2 = 96.7%; Tau2 = 2.361) and also cancer incidence (SIR = 1.54; 95% CI: 0.68–3.47; P = 0.229; I2 = 97.5%; Tau2 = 2.287), yet statistical significance was observed for second neoplasm (RR = 1.77; 95% CI: 1.33–2.35; P = 0.001; I2 = 26.7%; Tau2 = 0.055). Differences in the geographic region, gender, treatment duration, mean rhGH dose, overall rhGH exposure dose, and initial disease accounted for heterogeneity in the subgroup analyses.ConclusionOur findings indicate that the rhGH therapy is not related to all-cause mortality and cancer mortality and cancer incidence, yet it seems to trigger a second tumor risk. Future prospective studies are needed to confirm our findings and answer the more challenging question regarding the optimal dose of rhGH therapy in children and adolescents.
Kredit Bank Dan Sewa Guna Usaha Dengan Hak Opsi Sebagai Sumber Pendanaan Alternatif Atas Perolehan Aktiva Tetap Dalam Rangka Penghematan Pajak
Authors: Widyastuti Maria 
Published: April 2022

Banyak cara dan metode yang bisa dipilih oleh perusahaan dalam rangka mendapatkan dana untuk mengembangkan usahanya antara lain dengan cara mendapatkan kredit dari bank, pembelian aktiva secara angsuran, dan menyewa guna usaha aktiva dari perusahaan sewa guna usaha. Pada kenyataannya, banyak perusahaan kecil kesulitan mencari sumber dana melalui kredit perbankan dan pembelian aktiva secara angsuran sudah tidak memungkinkan lagi. Hanya perusahaan besar dan sudah mempunyai 'nama' saja yang mungkin dapat dengan mudah mendapatkan kepercayaan baik dari bank sebagai pihak yang memberi pinjaman maupun dari perusahaan yang menjual aktiva secara angsuran. Bagi perusahaan kecil semacam ini, sewa guna usaha (leasing) merupakan salah satu alternatif yang patut diberi rekomendasi untuk memecahkan masalah tersebut. Tujuan penelitian ini untuk mencari solusi yang tepat untuk memperoleh modal usaha berupa aktiva tetap yang murah dan tidak membebani arus kas keluar serta dapat menghemat pembayaran pajak. Pemilihan altematif pembiayaan kali ini penulis mencoba untuk membandingkan dua pilihan yaitu Kredit Bank dengan Sewa Guna Usaha (leasing). Teknik analisa yang digunakan adalah: (1) Menentukan nilai angsuran (annuitas); (2) Membebankan semua biaya fiskal yang melekat pada aktiva tetap; (3) Menghitung penghematan pajaknya; (4) Menghitung arus kas yang telah dikeluarkan; (5) Mengakumulasikan Net Present Value. Semakin kecil net present value-nya maka semakin hemat biaya yang dikeluarkan untuk memperoleh aktiva tetap tersebut. Uji Kasus dilaksanakan pada C.V. Hasta Corporation yang rencananya akan membeli aktiva tetap berupa Web Server Mainframe Machine, dengan harga perolehan Rp 999.000.000,-. Untuk memperoleh mesin tersebut pihak manajemen C.V. Hasta Corporation menentukan dua pilihan yaitu melalui Kredit Bank atau Sewa Guna Usaha (leasing). Ternyata dari basil penelitian menunjukkan bahwa Sewa Guna Usaha (leasing) lebih menguntungkan daripada Kredit Bank, keuntungan yang diperoleh adalah berupa penghematan pajak sebesar Rp 20.214.877,- sehingga berakibat pada net present value-nya menjadi lebih kecil.
Agency Theory Dalam Keputusan Keuangan: Sebuah Tinjauan Teoritis
Authors: Herdinata Christian 
Published: April 2022

Agency Theory bases its contractual relationships between principals and agents. Principal is the party that mandates the agency to act on behalf of the principal, while the agent is given the assignment by the principal to run the company. This study explains more about the agency theory in financial decision. Themanagement (agents )in performing the operation should give priority to the interests of the owner of the company by increasing the prosperity of the shareholders, but management will often have different interests with shareholder interests, giving rise to conflicts of interest between management and shareholders. Therefore, the necessary mechanisms to control agency conflicts that occur: first, increase company stock ownership by management and secondly,increased financing with debt; third, with monitoring by institutional investors, and the fourth, Dividend Payout Ratio via increased (DPR) or the ratio of dividends to net income are thus not enough free cash flow and forced to mancari management of external funding to finance its investment.
Pengaruh Manajemen Laba Terhadap Cost Of Equity Capital
Authors: Yuniarsih Nia 
Published: April 2022

The objective of this study is to examine the influence of earings management, to cost of equity capital. This study takes sample from 47 companies in the manufacturing sector at the Indonesia Stock Exchange (IDX), which were published in financial report from 2012-2013. The sample was determined based on the following criteria: (a) the annual report ended 31 December, and (b) book value of equity is positive. Earnings management were measured by Modified Jones Model and cost of equity capital was estimated by Capital Asset Pricing Market. The research hypotheses were tested using single regression. The results of this research show that earnings management had positive significant influence on cost of equity capital.
The time course of holistic processing is similar for face and non-face Gestalt stimuli
Authors: Curby Kim M. , Teichmann Lina 
Published: April 2022

AbstractThere is evidence that holistic processing of faces and other stimuli rich in Gestalt perceptual grouping cues recruit overlapping mechanisms at early processing stages, but not at later stages where faces and objects of expertise likely overlap. This has led to suggestions of dual pathways supporting holistic processing; an early stimulus-based pathway (supporting processing of stimuli rich in perceptual grouping cues) and an experience-based pathway (supporting processing of object of expertise), with both pathways supporting face processing. Holistic processing markers are present when upright faces are presented for as little as 50-ms. If the overlap between holistic processing of faces and stimuli rich in grouping cues occurs early in processing, markers of holistic processing for these Gestalt stimuli should be present as early as those for faces. In Experiment 1, we investigate the time-course of the emergence of holistic processing markers for face and non-face Gestalt stimuli. The emergence of these markers for faces and the Gestalt stimuli was strikingly similar; both emerged with masked presentations as little as 50-ms. In Experiment 2, where the stimulus presentation was not masked, thus the presentation duration, but not the post-presentation perceptual processing, was constrained, patterns of holistic processing for these stimuli still did not diverge. These findings are consistent with an early, and possibly extended, temporal locus for the overlap in the holistic processing of faces and non-face stimuli rich in grouping cues.
Asteroid Polarimetric Phase Behavior in the Near-infrared: S- and C-complex Objects
Authors: Masiero Joseph R. , Tinyanont S. , Millar-Blanchaer Maxwell A. 
Published: April 2022

Abstract
We present the first results of our survey of asteroid polarization phase curves in the near-infrared J and H bands using the WIRC+Pol instrument on the Palomar 200-inch telescope. We confirm through observations of standard stars that WIRC+Pol can reach the 0.1% precision needed for asteroid phase curve characterization, and we show that C-complex asteroids could act as an alternate calibration source, as they show less wavelength variation than stellar polarized standards. Initial polarization phase curve results for S-complex asteroids show a shift in behavior as a function of wavelength from visible to near-infrared bands, extending previously observed trends. Full near-infrared polarization phase curve characterization of individual asteroids will provide a unique constraint on surface composition of these objects by probing the wavelength dependence of albedo and index of refraction of the surface material.
Psychologie sociale, communication et langage
Authors: Salès-Wuillemin Édith 
Published: April 2022

Résumé introductif Ce chapitre réalise une présentation des travaux réalisés dans deux champs de recherche : la théorie des représentations sociales et la théorie du contrat de communication, en soulignant les lignes de convergence. L’objectif est de montrer que bien que ces deux champs de recherche se soient développés de manière autonome, une articulation théorique et méthodologique est possible, elle ouvre des perspectives intéressantes pour un enrichissement mutuel. La théorie du contrat de communication offre un cadre de recherche pour la mise en place d’un paradigme de recueil des données en raison de l’analyse des facteurs contextuels en jeu dans la situation d’expérimentation ou d’enquête. À l’inverse la théorie des représentations sociales, ouvre l’étude aux connaissances des sujets en situant les référents auxquels renvoient les mots de la langue dans un contexte social mettant en jeu des rapports intergroupes identifiés .
Des bureaucraties poreuses ? Les interactions de la commission européenne et du secrétariat du conseil avec leur environnement, et leur influence sur leurs préférences en termes de gouvernance
Authors: Alayrac Pierre , Connolly Sara , Kassim Hussein , Vantaggiato Francesca 
Published: April 2022

Les institutions européennes et les personnes qui travaillent pour elles sont souvent considérées comme repliées sur elles-mêmes et leurs ambitions : la Commission européenne est dépeinte comme une technocratie distante, et le Secrétariat du Conseil est considéré comme secret et renfermé. Cet article soumet ces hypothèses à un test empirique et va à leur encontre. S’appuyant sur deux jeux de données originaux, il cartographie les pratiques d’interaction avec les acteurs extérieurs pour ces deux parties de l’administration de l’UE. Il montre non seulement que la Commission européenne et le Secrétariat du Conseil sont en contact permanent avec des acteurs extérieurs, mais aussi que leurs préférences en termes de gouvernance sont affectées par ces contacts, quoique dans des mesures différentes.
Un regard sur l’Europe depuis la cour des comptes européenne
Authors: Lamarque Danièle 
Published: April 2022

Nommée à la Cour des comptes européenne en 2014, pour un mandat de 6 ans qui clôturait ma vie professionnelle, je rejoignais l’institution après trente ans de magistrature à la Cour des comptes française et dans les chambres régionales. Je savais toutefois que cette expérience ne me serait que partiellement utile dans une institution comparable par les missions et les modalités d’exercice professionnel, mais originale parce qu’européenne. Même si j’avais assidûment fréquenté la Cour de Luxembourg dans l’exercice de mes cinq années de directrice des relations internationales rue Cambon, il me restait à découvrir l’institution de l’intérieur et à mieux comprendre, à travers elle, l’Europe.
Le personnel du secrétariat général du Conseil au prisme des réformes néomanagériales : entre désingularisation et dédifférenciation
Authors: Gilloz Oriane 
Published: April 2022

Cet article esquisse une sociologie politique du personnel du Secrétariat général du Conseil de l’Union européenne (SGC). Après avoir montré que le personnel du SGC représente une déclinaison singulière du fonctionnariat européen façonnée par un triple processus d’identification, on se demande dans quelle mesure les réformes néomanagériales lancées en 2016 érodent la singularité identitaire qui caractérisait les fonctionnaires du Conseil jusqu’à présent. L’hypothèse défendue ici est que les transformations en cours s’inscrivent dans un double mouvement : un mouvement de dédifférenciation semblable à celui qui s’est opéré à la Commission et qui, à sa façon, poursuit la remise en jeu de l’autonomie partielle conquise par le champ bureaucratique européen (Georgakakis, 2019 et sa contribution dans le n o 180 de cette revue) ; et un mouvement de désingularisation qui tend à remettre sociologiquement en cause la spécificité du Conseil comme institution de type diplomatique et au service de la présidence.
Corps perdu d’Aimé Césaire et de Pablo Picasso, un recueil de guerres et de paix
Authors: Véron Kora 
Published: April 2022

En juin 1950, un livre magnifique, Corps perdu, tiré à 220 exemplaires, paraît aux Éditions Fragrance. En page de couverture, le nom d’Aimé Césaire s’affiche en haut, mais, en-dessous, celui de Pablo Picasso est beaucoup plus grand. Comment les deux hommes en sont-ils venus à publier ce recueil ? Comment ont-ils élaboré leur œuvre commune ? Corps perdu est l’aboutissement d’une histoire tumultueuse.
Exploration iconographique des manuscrits d’André Schwarz-Bart
Authors: Margras Fanny 
Published: April 2022

On connaît André Schwarz-Bart romancier : mais les dessins présents dans les manuscrits de l’écrivain sont un aspect encore méconnu de sa création. Cet article vise à présenter trois des quelques dessins d’André Schwarz-Bart retrouvés dans ses manuscrits. Ils sont tout à la fois ceux de l’écrivain happé par l’acte de créer, explorant une autre forme de dialogue avec son lecteur ; et ceux de l’écrivain lisant, donnant une forme aux pensées suggérées par sa lecture. Nous explorerons ce lien qui se tisse alors entre la lecture et la création chez André Schwarz-Bart par le biais du dessin.
Éléments pour une sociologie de l’activité de programmation
Authors: Jaton Florian 
Published: April 2022

Les multiples fonctionnements numériques – algorithmes inclus – qui participent à nos actions quotidiennes se doivent de passer, d’une manière ou d’une autre, par les mains expertes de programmeur·euse·x·s capables de traduire désirs, plans et intuitions en listes d'instructions exécutables par une machine informatique. Pour autant, ce travail concret de façonnage de programmes n’a que peu fait l’objet d’études de terrain détaillées. Si l’on compare les quelques rares enquêtes, importantes mais isolées, à la massivité de la programmation en tant qu’activité située dont les produits ne cessent d’irriguer nos sociétés informatisées, le contraste est inouï : tout reste à faire, ou presque. Prenant acte de la situation, cet article propose quelques outils et analyses pour tenter de la changer. Dans un premier temps, il expose une technique d’investigation, ainsi qu’un formalisme, permettant de rester au plus près du déroulement séquentiel des situations de programmation. Dans un deuxième temps, il analyse des matériaux récoltés selon cette méthode d’enquête – nommée ici sociologie de l’activité de programmation – et suggère qu'une part importante des pratiques de codage consiste, parfois, à aligner des inscriptions afin de renseigner l’état d’entités distantes (interpréteurs, compilateurs, processeurs) et, en retour, indexer un emplacement au sein d’un document numéroté. L’article finit par discuter les perspectives nouvelles sur l‘étude sociale du code induites par cette démarche analytique.