bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role ofStaphylococcus agnetisandStaphylococcus hyicusin the pathogenesis of buffalo fly skin lesions in cattle
Authors: Naseem Muhammad Noman , Turni Conny , Gilbert Rosalind , Raza Ali , Allavena Rachel , McGowan Michael , Constantinoiu Constantin , Ong Chian Teng , Tabor Ala E. , James Peter 
Published: March 2022

AbstractBuffalo flies (Haematobia irritans exigua) are hematophagous ectoparasites of cattle causing production and welfare impacts in northern Australian herds. Skin lesions associated with buffalo fly infestation andStephanofilarianematode infection are manifested as focal dermatitis or ulcerated areas most commonly on the medial canthus of the eye, along the lateral and ventral neck and on the abdomen of cattle. For closely related horn flies (Haematobia irritans irritans),Staphylococcus aureushave been suggested as a contributing factor in the development of lesions. To investigate the potential role of bacterial infection in the pathogenesis of buffalo fly lesions, swabs were taken from lesions and normal skin, and bacteria were also isolated from surface washings of buffalo flies and surface-sterilised homogenized flies. Bacterial identification was conducted by MALDI-TOF, strain typing by rep-PCR and DNA sequencing to determine species similarity and virulence factors. Of 49 bacterial isolates collected from lesions, 37 were identified asStaphylococcus agnetisand 12 asStaphylococcus hyicus, whereas from normal skin four isolates wereS. hyicusand one wasStaphylococcus sciuri. Of theStaphylococcusisolates isolated from buffalo flies, five were identified asS. agnetisand three asS. hyicus. Fifty percent of the buffalo fly isolates had rep-PCR genotypic patterns identical to the lesion isolates. Genome sequencing of 16S. agnetisand fourS. hyicusisolates revealed closely similar virulence factor profiles, with all isolates possessing exfoliative toxin A and C genes. The findings from this study suggest the involvement ofS. agnetisandS. hyicusin buffalo fly lesion pathogenesis. This should be taken into account in the development of effective treatment and control strategies for lesions.
Cryo-EM structure of amyloid fibril formed by α-synuclein hereditary A53E mutation
Authors: Sun Chuanqi , Zhou Kang , DePaola Peter , Shin Woo Shik , Hillyer Trae , Sawaya Michael R. , Zhou Z. Hong , Jiang Lin 
Published: March 2022

AbstractSynucleinopathies, including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple systems atrophy (MSA) have the same hallmark pathologic feature of misfolded α-synuclein protein accumulation in the brain. PD patients who carry α-syn hereditary mutations tend to have an earlier onset and more severe clinical symptoms and pathology than sporadic PD patients who carry wild-type (WT) α-syn. Therefore, revealing the structural effect of α-syn hereditary mutations on the wild-type fibril structure can help us understand synucleinopathies’ structural basis. Here, we present a 3.38 Å cryo-electron microscopy structure of α-synuclein fibrils containing the hereditary A53E mutation. The A53E fibril is symmetrically composed of two protofilaments, as are many other synucleopathic structures – including WT. Interestingly, the interface between the protofilaments in A53E has significantly less buried surface area than all other documented fibril structures of α-syn and its other mutants. The A53E fibril also exhibits slower formation/growth in in vitro fibrillation experiment compared to other mutants. This implies that the structural differences - both in the protofilament and between each protofilament of A53E – change the aggregation mechanism, or in the least, its kinetics of formation. These differences influence the molecular characteristics of each fibril mutant and likely plays a macro-scale role in progressing one clinical pathology over another.
Exploring the link between learning from error climate and professionals' engagement in social learning activities after errors
Authors: Smeets Laura , Gijselaers Wim , Meuwissen Roger , Grohnert Therese 
Published: March 2022

PurposeLearning from errors is a complex process that requires careful support. Building on affective events theory, the purpose of this paper is to explore how a supportive learning from error climate can contribute to social learning from errors through affective and cognitive error responses by individual professionals.Design/methodology/approachA total of 139 early-career auditors completed an online questionnaire consisting of validated survey scales, allowing for serial mediation analysis to compare direct and indirect effects.FindingsLearning from error climate was directly and positively related to engagement in social learning activities after committing an error. Furthermore, the authors found a double mediation by error strain (an affective error response) and reflecting on errors (a cognitive error response) on this relationship.Practical implicationsOrganizations can actively encourage professionals to learn from their errors by creating a supportive learning from error climate and holding professionals accountable for their errors.Originality/valueThe present study enriches the authors’ understanding of the mechanisms through which learning from error climate influences engagement in social learning activities. It extends prior research on learning from errors by investigating the sequential effects of engagement in error-related learning activities performed individually and in social interaction.
Understanding open data business models from innovation and knowledge management perspectives
Authors: Corrales-Garay Diego , Ortiz-de-Urbina-Criado Marta , Mora-Valentín Eva-María 
Published: March 2022

PurposeThis paper aims to analyse the open data business models (ODBMs) as a source of knowledge and innovation to generate economic and social value. A framework for understanding ODBMs is presented. First, the knowledge structure of the ODBMs literature is identified. Second, a conceptual model for analysing the ODBMs is proposed. And finally, the future trends in ODBMs research are discussed.Design/methodology/approachIn this paper, co-word analysis is performed to identify the topics related with ODBMs.FindingsThe ODBMs structure of knowledge is articulated in five themes: business model, smart city, business ecosystem, decision-making and innovation. Based on these results, a five-step model for analysing ODBMs is proposed. Finally, a discussion of the future trends of ODBMs focussed on a knowledge management perspective, open data ecosystems and business intelligence is presented.Originality/valueThe paper presents a picture of what, where, for whom and for what ODBMs have been studied and develops a new model to explain the value creation process of ODBMs. Taking a step further, applying the principles and models of knowledge management and business intelligence to ODBMs is also recommended in order to transfer and transform open data into valuable knowledge that can be used for developing apps. In that context, the importance of encouraging collaboration between different agents in the so-called open data ecosystem is presented.
Overeducation wage penalty among Ph.D. holders: an unconditional quantile regression analysis on Italian data
Authors: Gaeta Giuseppe Lucio , Lubrano Lavadera Giuseppe , Pastore Francesco 
Published: March 2022

PurposeThe wage effect of job–education vertical mismatch (i.e. overeducation) has only recently been investigated in the case of Ph.D. holders. The existing contributions rely on ordinary least squares (OLS) estimates that allow measuring the average effect of being mismatched at the mean of the conditional wage distribution.Design/methodology/approachThe authors implement a recentered influence function (RIF) to estimate the overeducation gap along the entire hourly wage distribution and compare Ph.D. holders who are overeducated with those who are not on a specific sample of Ph.D. holders in different fields of study and European Research Council (ERC) categories. Moreover, the authors compare the overeducation gap between graduates working in the academic and non-academic sector.FindingsThe results reveal that overeducation hits the wages of those Ph.D. holders who are employed in the academic sector and in non-research and development (R&D) jobs outside of the academic sector, while no penalty exists among those who carry out R&D activities outside the academia. The size of the penalty is higher among those who are in the mid-top of the wage distribution and hold a Social Science and Humanities specialization.Practical implicationsTwo policies could reduce the probability of overeducation: (a) a reallocation of Ph.D. grants from low to high demand fields of study and (b) the diffusion of industrial over academic Ph.Ds.Originality/valueThis paper observes the heterogeneity of the overeducation penalty along the wage distribution and according to Ph.D. holders' study field and sector of employment (academic/non-academic).
Investigating boycotts and buycotts as antecedents towards attitude and intention to engage in ethical consumption
Authors: Akintimehin Olamide , Phau Ian , Ogbechie Rose , Oniku Ayodele 
Published: March 2022

Purpose
This paper aims to investigate the attitude towards ethical consumption and intention to engage in ethical consumption behaviour by consumers within a developing economy, building on the ethically minded consumer behaviour (EMCB) framework.

Design/methodology/approach
A quantitative research approach was adopted in this research. A cross-sectional survey was further done in collecting data from 397 respondents through an online questionnaire. Collected data was analysed using the Statistical Package for Social Sciences version 25, as well as the structural equation model via the Analysis of Moment Structures version 23.

Findings
Corporate social responsibility-mindedness was found to lead to a positive attitude towards ethical consumption behaviour and an intention to engage in ethical consumption behaviour; recycling-mindedness did not influence a positive attitude towards ethical consumption behaviour but influenced an intention to engage in ethical consumption behaviour. However, eco-mindedness did not influence a positive attitude towards ethical consumption behaviour and an intention to engage in ethical consumption behaviour: findings from this research showed that a positive attitude towards ethical consumption behaviour led to an intention to engage in ethical consumption behaviour.

Originality/value
To the best of the authors’ knowledge, this research is the first within a Sub-Saharan African region of a developing economy to adapt the EMCB framework in investigating the extent to which consumers within a developing economy intend to engage in ethical consumption behaviour.
Individuals' fixed digital mindset, internal HRM alignment and feelings of helplessness in virtual teams
Authors: Wong Sut I , Solberg Elizabeth , Traavik Laura 
Published: March 2022

PurposeThe present study investigates whether individuals having a fixed digital mindset (comprises fundamental beliefs about technological ability and organizational resources as work becomes more digitalized) experience greater helplessness working in virtual teamwork environments. The authors examine how perceived internal human resource management (HRM) alignment moderates the positive relationship expected between individuals' fixed digital mindset and feelings of helplessness. Together, the paper aims to contribute to a greater understanding of the personal and contextual factors that influence an individual's experience of helplessness in virtual team settings.Design/methodology/approachThe authors test the hypotheses using time-lagged survey data collected from 153 information technology (IT) engineers working in virtual teams in Europe.FindingsThe authors find that individuals with higher levels of fixed digital mindset experience greater helplessness in virtual teamwork environments than individuals with lower levels. Furthermore, the authors find that having higher-fixed beliefs about organizational resources is positively related to helplessness when individuals perceive that the broader HRM system is misaligned with the virtual teamwork environment.Research limitations/implicationsThe data were obtained from IT engineers in Europe, which is potentially limiting the generalizability of the authors' findings to other work contexts and cultures.Practical implicationsThe authors' study helps leaders in virtual teamwork environments to better understand and manage the personal and contextual factors that could affect individuals' well-being and effective functioning in such settings.Originality/valueThe authors' research contributes to the scant literature investigating the personal characteristics important in virtual teamwork environments and the contextual factors important for aligning virtual teamwork designs with the organizational system. The authors extend this research by looking at personal and contextual factors together in a single model.
Shaping path of trust: the role of information credibility, social support, information sharing and perceived privacy risk in social commerce
Authors: Tseng Hsiao-Ting 
Published: March 2022

PurposeCurrently, the Covid-19 pandemic is changing how consumers shop, encouraging deeper levels and increased reliance on e-commerce systems and social media such as online communities. The online interaction of consumers is more important and brings many uncertainties, which impact the original commerce environment. This study aim to investigate the ethical consideration of information credibility and perceived privacy risk from a psychology perspective in marketing, this study draws on social support theory from social psychology to develop a research model to investigate the role of information credibility and perceived privacy risk on social commerce websites.Design/methodology/approachThis study investigated social commerce websites and communities. The research data of this study was collected through a questionnaire from consumers on three famous social commerce platforms. Using PLS-SEM to perform data analysis, this study research the importance of information credibility, perceived privacy risk and trust on social commerce websites.FindingsThe findings discuss individuals' reaction to privacy issues and to understand the motives to disclose or reveal personal information within a marketing or consumption context. The research also explores the theoretical implications by integrating theories from information systems and social psychology to investigate ethical issues in social commerce.Originality/valueCovid-19 makes peer-to-peer communication in online communities is developing collaborative consumption, and information produced in these communities can influence the decisions of consumers. Covid-19 has exacerbated such a change in social commerce environment. Therefore, information credibility plays an important role in developing online communities. It is important to look at the psychological antecedents that drive consumers' willingness to share their personal information when using online communities. The author has clarified which aspects of trust in social commerce should be strategized, including information trustworthiness, perceived privacy risks, social support and information sharing. These are the details that companies should pay more attention to when operating social commerce. Only by paying more attention to these details and giving consumers a positive feeling can consumers' trust be maintained or enhanced, ultimately leading to a successful trust economy.
The intricate relationships of consumers’ loyalty and their perceptions of service quality, price and satisfaction in restaurant service
Authors: Ahmed Selim , Al Asheq Ahmed , Ahmed Ezaz , Chowdhury Ujjal Yaman , Sufi Tahir , Mostofa Md. Golam 
Published: March 2022

PurposeThe purpose of this study is to determine how consumers perceive restaurant service in Bangladesh. The goal of this study is to determine the impact of perceived service quality and price fairness on consumer satisfaction and loyalty toward restaurant services.Design/methodology/approachThe data for this study were collected from 326 respondents who have used restaurant services in Bangladesh. Partial Least Squares Structural Equation Modeling (PLS-SEM) was used to evaluate the research data with SmartPLS 3.3.3.FindingsThe current study’s findings indicate that perceived service quality and price fairness both have a direct and significant effect on consumer satisfaction. Additionally, the research findings reveal a considerable association between perceived pricing fairness and consumer pleasure and consumer loyalty. Additionally, findings indicate that perceived service quality and price fairness both have a significant indirect effect on customer loyalty via the mediating effect of consumer satisfaction.Practical implicationsThe current study demonstrates that perceived price fairness has a substantial effect on restaurant consumers’ satisfaction and loyalty; thus, this evidence can assist restaurant owners and managers in developing and implementing their pricing strategy to retain customers. Additionally, the findings have significant implications for restaurant operators, practitioners and policymakers.Originality/valueOnly a few research have been conducted to determine the effect of service quality and pricing fairness on consumer satisfaction and loyalty when it comes to restaurant services. This research conclusion provides guidance to service providers on how to increase customer satisfaction and loyalty through an emphasis on price fairness and service quality.
Ecological engineering across a spatial gradient: Sociable weaver colonies facilitate animal associations with increasing environmental harshness
Authors: Lowney Anthony M. , Thomson Robert L. 
Published: March 2022

Abstract

The spatial distribution of animals in a landscape depends mainly on the distribution of resources. Resource availability is often facilitated by other species and can positively influence local species diversity and affect community structure. Species that significantly change resource availability are often termed ecosystem engineers. Identifying these species is important, but predicting where they have large or small impacts is a key challenge that will enhance the usefulness of the ecosystem engineering concept.

In harsh and stressful environments, the stress gradient hypothesis predicts that community structure and function will be increasingly influenced by facilitative interactions.

To test this hypothesis, we investigate how the ecosystem engineering role and importance of sociable weavers Philetairus socius varies across a spatial gradient of harshness, for which aridity served as a proxy. These birds build large colonies that are home to hundreds of weavers and host a wide range of avian and non‐avian heterospecifics. We investigated the use of weaver colonies on multiple taxa (invertebrates, reptiles, birds and mammals) at multiple sites across a >1,000 km aridity gradient.

We show that sociable weaver colonies create localized biodiversity hotspots across their range. Furthermore, trees containing sociable weaver colonies maintained localized animal diversity at sites with lower rainfall, an effect not as pronounced at sites with higher rainfall.

Our results were consistent with predictions of the stress gradient hypothesis, and we provide one of the first tests of this hypothesis in terrestrial animal communities. Facilitation and amelioration by ecosystem engineers may mitigate some of the extreme impacts of environmental harshness.
Citri Reticulatae Pericarpium alleviates postmyocardial infarction heart failure by upregulating PPARγ expression
Authors: Chen Mengli , Zhu Hongyan , Zhu Qingqing , Wu Xiaodong , Zhou Yufei , Gao Rongrong , Shi Mengsha , Zhang Ting , Yin Ting , Zhang Haifeng , Shang Hongcai , Li Xinli 
Published: March 2022

AbstractHeart failure after myocardial infarction (MI) is the leading cause of death worldwide. Citri Reticulatae Pericarpium (CRP) is a traditional Chinese herbal medicine that has been used in the clinic for centuries. In this study, we aimed to investigate the roles of CRP in cardiac remodelling and heart failure after MI, as well as the molecular mechanisms involved. Male C57BL/6 mice aged 8 weeks were subjected to coronary artery ligation to mimic the clinical situation in vivo. Echocardiography was used to assess the systolic function of the mouse heart. Masson trichrome staining and Wheat germ agglutinin (WGA) staining were utilised to determine the fibrotic area and cross‐sectional area of the mouse heart, respectively. Cardiomyocytes and fibroblasts were isolated from neonatal rats aged 0–3 days in vitro using enzyme digestion. TUNEL staining and EdU staining were performed to evaluate apoptosis and proliferation, respectively. Gene expression changes were analysed by qRT–PCR, and protein expression changes were assessed by Western blotting. Our findings revealed that CRP attenuated cardiac hypertrophy, fibrosis and apoptosis and alleviated heart failure after MI in vivo. Furthermore, CRP mitigated cardiomyocyte apoptosis and fibroblast proliferation and differentiation into myofibroblasts. In addition, the PPARγ inhibitor T0070907 completely abolished the abovementioned beneficial effects of CRP, and the PPARγ activator rosiglitazone failed to further ameliorate cardiac apoptosis and fibrosis in vitro. CRP alleviates cardiac hypertrophy, fibrosis, and apoptosis and can ameliorate heart failure after MI via activation of PPARγ.
Energy‐conserving dimethyl sulfoxide reduction in the acetogenic bacterium Moorella thermoacetica
Authors: Rosenbaum Florian P. , Poehlein Anja , Daniel Rolf , Müller Volker 
Published: March 2022

SummaryMoorella thermoacetica is one of the well‐studied thermophilic acetogenic bacteria. It grows by oxidation of organic substrates, CO or H2 coupled to CO2 reduction to acetate. Here, we describe that M. thermoacetica can also use dimethyl sulfoxide as terminal electron acceptor. Growth of M. thermoacetica on glucose or H2 + CO2 was stimulated by dimethyl sulfoxide (DMSO). Membranes showed a DMSO reductase activity, that was induced by growing cells in presence of DMSO. The enzyme used reduced anthraquinone‐2,6‐disulfonate, benzyl‐ and methyl viologen as electron donor, but not NAD(P)H. Activity was highest at pH 5 and 60°C, the Km for DMSO was 2.4 mM. Potential DMSO reductase subunits were identified by peptide mass fingerprinting; they are encoded in a genomic region that contains three potential dmsA genes, three dmsB genes and one dmsC gene. Transcriptome analysis revealed that two different dmsAB gene clusters were induced in the presence of DMSO. The function of these two and their predicted biochemical features are discussed. In addition, the data are in line with the hypothesis that M. thermoacetica can use DMSO alongside CO2 as electron acceptor and DMSO reduction is catalysed by an energy‐conserving, membrane‐bound electron transport chain with DMSO as final electron acceptor.