bluuebunny/crossref_metadata_2025_split huggingface dataset:
The spillover effects of financial misconduct on the value of cash of peer firms
Authors: Palkar Darshana D. 
Published: February 2022

PurposePrior research has documented a guilt by association phenomenon whereby instances of corporate misconduct generate a negative spillover to innocent firms due to their shared industry membership with the wrongdoing firm. However, research on competitive dynamics predicts a positive spillover whereby some firms benefit from the revelation of financial misconduct by an industry peer. This study lends support to both these effects by highlighting the role product similarity plays in the understanding of investors' perceptions surrounding corporate misconduct.Design/methodology/approachThe study assesses the investors' valuation of cash using Faulkender and Wang's (2006) methodology. The difference-in-differences approach is employed to compare the market valuation of cash held by non-accused firms with higher and lower litigation spillover risk operating in industries with higher vs lower product similarity.FindingsThe findings show that an increase in the volume and severity of misconduct by industry peers is associated with an undeserved loss in the value of cash held by non-accused firms operating in industries with high product similarity. In contrast, firms that sell differentiated products stand to gain from the troubles of the accused peer. Moreover, non-accused firms in industries with high product similarity reduce capital expenditures more following misconduct accusations against peers to preserve cash in anticipation of future lawsuits.Originality/valueThis study contributes to the growing spillover literature that investigates how a crisis caused by one firm affects the valuation of its peers.
Preparation and characterization of doped LiZn0.92Cu0.08PO4 ceramic for microwave and millimeter-wave substrates
Authors: Synkiewicz-Musialska Beata , Szwagierczak Dorota , Kulawik Jan , Czerwińska Elżbieta 
Published: February 2022

Purpose
This paper aims to report on fabrication procedure and presents microstructure and dielectric behaviour of LiZn0.92Cu0.08PO4 ceramic material with Li2CO3 as a sintering aid.

Design/methodology/approach
Substrates based on LiZn0.92Cu0.08PO4 with Li2CO3 addition were prepared via solid-state synthesis, doping, milling, pressing and sintering. Characterization of the composition, microstructure and dielectric properties was performed using X-ray diffractometry, energy dispersive spectroscopy, scanning electron microscopy, impedance spectroscopy in the 100 Hz to 2 MHz range and time-domain spectroscopy in the 0.1–3 THz range.

Findings
Doped LiZnPO4 ceramic, which exhibits a low dielectric constant of 5.9 at 1 THz and low sintering temperature of 800 °C, suitable for low temperature co-fired ceramics (LTCC) technology, was successfully prepared. However, further studies are needed to lower dielectric losses by optimising the doping level, synthesis and sintering conditions.

Originality/value
Search for new low dielectric constant materials applicable in LTCC technology and optimization of processing are essential tasks for developing modern microwave circuits. The dielectric characterization of doped LiZnPO4 ceramic in the terahertz range, which was performed for the first time, is crucial for potential millimetre-wave applications of this substrate material.
Overcoming overtourism: a review of failure
Authors: Butler Richard William , Dodds Rachel 
Published: February 2022

PurposeThe purpose of this paper is to identify and review attempts at mitigation and prevention of overtourism and to outline reasons for the failure to date of such efforts.Design/methodology/approachThis paper is a perspective paper and draws on an examination of relevant literature on the subject through the lens of a conceptual framework. It outlines the changing roles of tourism development and marketing organisations and the failure of public sector agencies to control and manage tourism. The varying methods of limiting tourist numbers are examined, and their weaknesses are presented.FindingsConclusions reveal that there are a series of global trends that are contributing to the appearance and continuation of overtourism and which, to date, are proving immune to mitigation and resolution for specific reasons. These include a lack of willingness to accept the problem of tourist numbers and to reduce or effectively manage these at all levels, from local to international.Research limitations/implicationsPresent approaches to mitigation need to be revisited and better integrated with management and control of all aspects of development and framed to achieve and retain political support at all levels.Originality/valueThere has been little attempt before to analyse the reasons for the failure to effectively mitigate or prevent overtourism, and this paper makes an original contribution in this area in that it is an evaluation of what is known and a summary of shortcomings within the industry and academia.
Pathways of savannization in a mesic African savanna–forest mosaic following an extreme fire
Authors: Beckett Heath , Staver A. Carla , Charles‐Dominique Tristan , Bond William J. 
Published: February 2022

Abstract

Fires in savannas limit tree cover, thereby promoting flammable grass accumulation and fuelling further frequent fires. Meanwhile, forests and thickets form dense canopies that reduce C4 grass fuel loads and creating a humid microclimate, thereby excluding fires under typical climatic conditions. However, extreme fires occasionally burn into these closed‐canopy systems. Although these rare fires cause substantial tree mortality and can make repeat fires more likely, the long‐term consequences of an extreme fire for closed‐canopy vegetation structure and potential to convert to savanna (hereafter ‘savannization’) remain largely unknown.

Here, we analysed whether an extreme fire could, alone, alter species composition, vegetation structure and fire regimes of closed‐canopy ecosystems in an intact savanna–forest–thicket mosaic, or whether successive fires after an initial extreme fire were necessary to trigger a biome transition from forest to savanna.

We found that forests that only burned once recovered, whereas those that burned again following an initial extreme fire transitioned from closed‐canopy forests towards open, grassy savannas. While thickets had less tree mortality in fires than forests, repeat fires nonetheless precipitated a transition towards savannas. Colonization of the savanna tree community lagged behind the grass community, but also began to transition.

Synthesis. Our results suggest that rare extreme fires, followed by repeated burning can indeed result in savannization in places where savanna and forest represent alternative stable states.
Sixty‐eight cases of postmortem pink teeth observed in dental autopsies of unidentified cadavers
Authors: Minegishi Saki , Utsuno Hajime , Ohta Jun , Namiki Shuuji , Toya Maiko , Sumi Nozomi , Unuma Kana , Saitoh Hisako , Iwase Hirotaro , Uemura Koichi , Sakurada Koichi 
Published: February 2022

AbstractThe pink teeth phenomenon was first reported in people who died by hanging or drowning in 1829. In recent years, there have been many reports that the occurrence of postmortem pink teeth is closely related to the condition of surroundings and time after death rather than to the cause of death, as had previously been thought. We observed pink teeth in 68 of 324 unidentified cadavers autopsied during 2015–2021, and we investigated the relationship of pink teeth with age, sex, cadaveric condition, time after death, tooth type, and cause of death. The results showed no significant differences in the occurrence of pink teeth according to sex or place of discovery (indoors, outdoors, or in water). Pink teeth tended to be observed below the age of 60 years. In the 68 cases with pink teeth, 29.1% of all vital teeth were affected, with the anterior teeth being most common. No evidence was found that supported an association between pink teeth and cause of death. These results are largely consistent with recent reports on postmortem pink teeth. As it stands, the pink teeth phenomenon may be nonspecific and must not be misinterpreted in medico‐legal investigations. This case series provides further evidence supporting recent reports and contributes to clarifying in greater detail the mechanisms of the coloration and fading of pink teeth.
Evaluation of sex attractants for monitoring ofIlliberis ulmivoraGraeser (Lepidoptera: Zygaenidae: Procridinae): Height, distance, placement, climatic conditions
Authors: Liu Hongxia , Dou Rui , Wang Jifei , Zhu Yachao , Li Jingyao , Liu Jinlong , Wang Yang , Zhang Jintong , Jing Xiaoyuan 
Published: February 2022

AbstractThe phytophagous caterpillarIlliberis ulmivorais a serious pest ofUlmus glaucescensFranch (Ulmaceae, Ulmus). In order to test potent sex attractant, field trailsof synthetic candidate attractants were conducted in China. In this study, baits with ternary blends, (2S)‐butyl (7Z)‐dodecenoate, (2S)‐butyl (9Z)‐tetradecenoate, and (2S)‐butyl (5Z)‐decenoate (8:4:1 ratio) resulted in a higher number of male moths capture than the rest of the baits that were offered. Traps positioned at a height of 1.2 m attracted more males than those installed at heights of 2.2 m and 3.2 m. The slope aspect, temperature and humility had a significant effect on the trap catches. More catches occurred in traps placed on semi‐shady and semi‐sunny slopes than those placed on sunny and shady slopes. The number of pheromones in the septa decreased with age. The residual amounts of pheromones in the lures combined with 2,6‐di‐tert ‐ butyl‐p‐cresol (BHT) were higher than those in the control. However, there were no differences in the male captures between components and components combined with BHT during the first 8 d. These findings on monitoring and trap positions can be used to predict the occurrence and population dynamics ofI. ulmivora, to develop ecological management ofI. ulmivora.
The impact of orthostatic intolerance on early ambulation following abdominal surgery in an enhanced recovery programme
Authors: Hardy Pierre‐Yves J‐P. , Tavano Alessandro , Jacquet Sophie V. , Monseur Justine J. , Bastin Marie‐Hélène L. , Kohnen Laurent P. , Haumann Alexandre E. , Joris Jean L. 
Published: February 2022

AbstractBackgroundThe prevalence of orthostatic intolerance on the day of surgery is more than 50% after abdominal surgery. The impact of orthostatic intolerance on ambulation on the day of surgery has been little studied. We investigated orthostatic intolerance and walking ability after colorectal and bariatric surgery in an enhanced recovery programme.MethodsEighty‐two patients (colorectal: n = 46, bariatric n = 36) were included and analysed in this prospective study. Walk tests for 2 min (2‐MWT) and 6 min (6‐MWT) were performed before and 24 h after surgery, and 3 h after surgery for 2‐MWT. Orthostatic intolerance characterised by presyncopal symptoms when rising was recorded at the same time points. Multivariate binary logistic regressions modelling the probability of orthostatic intolerance and walking inability were performed taking into account potential risk factors.ResultsPrevalence of orthostatic intolerance and walking inability was, respectively, 65% and 18% 3‐hour after surgery. The day after surgery, patients’ performance had greatly improved: approximately 20% of the patients experienced orthostatic intolerance, whilst only 5% of the patients were unable to walk. Adjusted binary logistic regressions demonstrated that age (p = .37), sex (p = .39), BMI (p = .74), duration of anaesthesia (p = .71) and type of surgery (p = .71) did not significantly influence walking ability.ConclusionOur study confirms that orthostatic intolerance was frequent (~ 60%) 3‐hour after abdominal surgery but prevented a 2‐MWT only in ~20% of patients. No risk factors for orthostatic intolerance and walking inability were evidenced.
Age‐related DNA methylation on Y chromosome and their associations with total mortality among Chinese males
Authors: Li Guyanan , Wang Chenming , Guan Xin , Bai Yansen , Feng Yue , Wei Wei , Meng Hua , Fu Ming , He Meian , Zhang Xiaomin , Lu Yanjun , Lin Yong , Guo Huan 
Published: February 2022

AbstractIn view of the sex differences in aging‐related diseases, sex chromosomes may play a critical role during aging process. This study aimed to identify age‐related DNA methylation changes on Y chromosome (ChrY). A two‐stage study design was conducted in this study. The discovery stage contained 419 Chinese males, including 205 from the Wuhan‐Zhuhai cohort panel, 107 from the coke oven workers panel, and 107 from the Shiyan panel. The validation stage contained 587 Chinese males from the Dongfeng‐Tongji sub‐cohort. We used the Illumina HumanMethylation BeadChip to determine genome‐wide DNA methylation in peripheral blood of the study participants. The associations between age and methylation levels of ChrY CpGs were investigated by using linear regression models with adjustment for potential confounders. Further, associations of age‐related ChrY CpGs with all‐cause mortality were tested in the validation stage. We identified the significant associations of 41 ChrY CpGs with age at false discovery rate (FDR) <0.05 in the discovery stage, and 18 of them were validated in the validation stage (p < 0.05). Meta‐analysis of both stages confirmed the robust positive associations of 14 CpGs and negative associations of 4 CpGs with age (FDR<0.05). Among them, cg03441493 and cg17816615 were significantly associated with all‐cause mortality risk [HR(95% CI) = 1.37 (1.04, 1.79) and 0.70 (0.54, 0.93), respectively]. Our results highlighted the importance of ChrY CpGs on male aging.
Complex drivers of phenology in the pine processionary moth: Lessons from the past
Authors: Martin Jean‐Claude , Mesmin Xavier , Buradino Maurane , Rossi Jean‐Pierre , Kerdelhué Carole 
Published: February 2022

Abstract
Climate change affects the life cycle of many species. Yet, responses to yearly variation of weather can either help species track optimal conditions or be maladaptive.
We analysed phenological data of 46,479 pine processionary moths (Thaumetopoea pityocampa) during 15 years along an altitudinal gradient in southern France. These larvae were sampled in situ and allowed to pupate in a common garden at lower elevation.
Individuals originating from higher elevation emerged earlier than those sampled at low elevation, which suggests local adaptation. Yearly variations in temperature also affected phenology. Warm springs caused an earlier adult emergence, while autumn temperatures had an opposite effect. Environmental cues could thus induce contradictory plastic responses.
Synchronization mechanisms were identified. Variability in the duration of the pupal phase is a key parameter to synchronize adult emergence in spite of different larval development rates that only marginally influenced emergence dynamics. Semivoltine individuals experiencing prolonged diapause were synchronized with univoltine individuals emerging the same year.
These data highlight some contradiction in the effect of spatial versus temporal variations of the temperature on adult emergence. This suggests that phenological responses to the current climate change cannot easily be anticipated by space‐for‐time substitution designs.
Breakthroughs at the disciplinary nexus: Rewards and challenges for applied economists
Authors: Khanna Madhu 
Published: February 2022

AbstractComplex societal challenges call for solutions that require innovative thinking and new ways of problem‐solving that creatively combine knowledge from multiple disciplines. It is imperative that applied economists engage in interdisciplinary research and apply systems thinking and analytical approaches to analyzing trade‐offs and behavioral drivers of human choices to design strategies to achieve societal goals. Agricultural and applied economics have a foundation in interdisciplinary research, real‐world problem solving and engagement with stakeholders, but face increasing pressures for specialization. This address discusses strategies for conducting interdisciplinary research that rely on T‐shaped research skills, team science and aggregating expertise from different disciplines to co‐develop solutions to challenging societal problems. It provides some examples of ground‐breaking research that has emerged in applied economics due to the collaborations with and insights provided by scholars from other disciplines. The paper concludes with a discussion of the institutional and discipline‐related challenges to conducting interdisciplinary research and a call to the profession to foster, recognize and value interdisciplinary research.
Publication rate of abstracts presented at the Australian Orthopaedic Association Annual Scientific Meeting
Authors: Balhatchet Belinda , Schütze Heike , Awais Anum , Williams Nicole 
Published: February 2022

AbstractBackgroundPresentations at scientific conferences are an important method of research dissemination, with abstracts often used to inform clinical practice. Abstract to publication ratio is a commonly used tool for determining meeting quality. The aim of this study was to determine the publication rate for abstracts presented at the Australian Orthopaedic Association Annual Scientific Meeting (AOA ASM) between 2012 and 2015 inclusive and identify reasons for non‐publication.MethodsMEDLINE, PubMed and Google Scholar were searched to determine whether each abstract presented at AOA ASMs between 2012 and 2015 was associated with a full text publication in a peer‐reviewed journal. Where a publication could not be located, the presenter was contacted to confirm the reason for non‐publication.ResultsA total of 1130 abstracts were submitted (951 oral and 179 posters), and 573 resulted in full‐text peer‐reviewed publications (51%). The majority of publications (73%) were published within 2 years of presentation. There was no difference in likelihood of publication for oral presentations compared to posters, nor in the rate of publication across the 4 years of meetings. Common reasons for non‐publication were lack of time (32%), publication considered low priority (27%) and journal rejections (22%).ConclusionThe overall publication rate for abstracts presented at the AOA ASM is 51%, which is an increase from the 1998 ASM (31%). This publication rate is higher than many similar Australian meetings and on par with other international orthopaedic and subspecialty meetings. Future research should investigate potential publication bias and methods to minimise barriers to publication.
Operative, long‐term and quality of life outcomes after salvage of failed re‐do ileal pouch anal anastomosis
Authors: Esen Eren , Lynn Patricio B. , Da luz Moreira Andre , Erkan Arman , Aytac Erman , Grieco Michael J. , Kirat Hasan T. , Remzi Feza H. 
Published: February 2022

AbstractAimApproximately 20%–40% of the patients with re‐do ileal pouch anal anastomosis (IPAA) experience pouch failure. Salvage surgery can be attempted in this patient group with severe aversion to permanent ileostomy. The literature regarding secondary IPAA revision after re‐do IPAA failure is scarce.MethodsAll patients who underwent a secondary IPAA revision after re‐do IPAA failure between September 2016 and July 2021 in a single centre were included. Short‐ and long‐term outcomes and quality of life in this patient group are reported.ResultsTen patients who had secondary IPAA revision for re‐do IPAA failure were included. All patients had ulcerative colitis. Nine of these patients had pelvic sepsis and one patient had a mechanical issue. Mucosectomy and handsewn anastomosis was performed in nine patients. The existing pouch was salvaged in six patients and four patients had pouch excision and re‐creation. Two patients had postoperative pelvic sepsis. Pouch retention rate was 78% in a median of 28 months. None of the patients had short‐gut syndrome. The procedure was associated with good quality of life (median Cleveland Global Quality of Life Index 0.8). All patients would undergo the same surgery if needed.ConclusionSecondary IPAA revision after a failed re‐do IPAA can be an option in patients with severe aversion to permanent ileostomy if re‐do IPAA fails and it is associated with good outcomes. This patient group should be carefully evaluated and referred to specialized centres if required.
Effect of enzalutamide on PK of P‐gp and BCRP substrates in cancer patients: CYP450 induction may not always predict overall effect on transporters
Authors: Poondru Srinivasu , Ghicavii Vitalii , Khosravan Reza , Manchandani Pooja , Heo Nakyo , Moy Selina , Wojtkowski Tomasz , Patton Melanie , Haas Gabriel P. 
Published: February 2022

AbstractDrug‐drug interaction (DDI) is an important consideration for clinical decision making in prostate cancer treatment. The objective of this study was to evaluate the effect of enzalutamide, an oral androgen receptor inhibitor, on the pharmacokinetics (PK) of digoxin (P‐glycoprotein [P‐gp] probe substrate) and rosuvastatin (breast cancer resistance protein [BCRP] probe substrate) in men with metastatic castration‐resistant prostate cancer (mCRPC). This was a phase I, open‐label, fixed‐sequence, crossover study (NCT04094519). Eligible men with mCRPC received a single dose of transporter probe cocktail containing 0.25 mg digoxin and 10 mg rosuvastatin plus enzalutamide placebo‐to‐match on day 1. On day 8, patients started 160 mg enzalutamide once daily through day 71. On day 64, patients also received a single dose of the cocktail. The primary end points were digoxin and rosuvastatin plasma maximum concentration (Cmax), area under the concentration‐time curve from the time of dosing to the last measurable concentration (AUClast), and AUC from the time of dosing extrapolated to time infinity (AUCinf). Secondary end points were enzalutamide and N‐desmethyl enzalutamide (metabolite) plasma Cmax, AUC during a dosing interval, where tau is the length of the dosing interval (AUCtau), and concentration immediately prior to dosing at multiple dosing (Ctrough). When administered with enzalutamide, there was a 17% increase in Cmax, 29% increase in AUClast, and 33% increase in AUCinf of plasma digoxin compared to digoxin alone, indicating that enzalutamide is a “mild” inhibitor of P‐gp. No PK interaction was observed between enzalutamide and rosuvastatin (BCRP probe substrate). The PK of enzalutamide and N‐desmethyl enzalutamide were in agreement with previously reported data. The potential for transporter‐mediated DDI between enzalutamide and digoxin and rosuvastatin is low in men with prostate cancer. Therefore, concomitant administration of enzalutamide with medications that are substrates for P‐gp and BCRP does not require dose adjustment in this patient population.