bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factores asociados al embarazo no deseado: Estudio analítico.
Authors: Vargas Rodríguez Ledmar J. , Niño Avendaño Carlos Alberto , Barón Sánchez Alfonso 
Published: April 2022

Objetivo: Determinar los factores asociados al embarazo no deseado en población adolescente. Materiales y métodos: Estudio transversal analítico. Personas con edades entre los 18 a 35 años de edad. Resultados: La edad promedio fue de 21.61 años. La mayoría de los encuestados pertenecían al género femenino (61%). Se determinó que las personas con pareja (OR 3.05), no uso planificación en la primera relación (OR 5.62), no usar algún método de planificación (OR 1.48), estrato socio-económico bajo/medio (OR 7.84), relación familiar mala (OR 2.40) y el uso de métodos naturales para planificar (OR 2.64) son factores de riesgo; mientras que obtener información por una persona del personal de salud (OR0.32) y la procedencia de zona urbana (OR 0.27) son factores protectores. Conclusiones: Podemos concluir así que la prevalencia de embarazos no deseados es variable en las distintas poblaciones, esto puede estar asociado a una sólida educación, donde se debe estimular el principio de la responsabilidad compartida y de que la pareja debe hacer frente sólidamente a las consecuencias de sus relaciones.
Polystemma fishbeiniana (Apocynaceae, Asclepiadoideae), a new species from the Balsas Depression of Michoacán, Mexico
Authors: Steinmann Victor W. , Stevens Warren D. 
Published: April 2022

Background: Polystemma (Apocynaceae subfamily Asclepiadoideae) is a small genus currently with seven species characterized by having white glandular trichomes becoming crystalline in age; filiform corona appendages; and fusiform, smooth, mottled follicles. Exploration in the Balsas Depression of Michoacán, Mexico resulted in the discovery of an unknown species of Polystemma .
Questions: Are the unknown Polystemma plants occurring in the Balsas Depression of Michoacán new to science? If so, how are they distinguished from other species of the genus, what are their ecological preferences, what is their distribution, and are they endangered?
Studied species: Species of Polystemma .
Study site and dates: Balsas Depression, Michoacán, México; 2001, 2003, 2004, 2014.
Methods: Fieldwork to collect herbarium specimens and photograph plants; review of literature on Polystemma to determine taxonomic status; preparation of a morphological description; evaluation of conservation status using IUCN Redlist criteria.
Results: Polystemma fishbeiniana is proposed as a new species and illustrated with photographs. It occurs at two locations in the xeric scrub and open thorn forest of the Zicuirán-Infiernillo Biosphere Reserve, at elevations from 275 to 400 m. Flowering occurs from June to September, with mature fruits present from October to March; dehisced fruits can persist on the plants for almost a year. Its conservation status is assessed as Endangered, EN B1ab(iii)+2ab(iii).
Conclusions: Polystemma fishbeiniana is distinguished from congeners by its suffrutescent habit, small leaves, and flowers abaxially yellowish with a blackish to dark burgundy red margin and central line with short lateral extensions.These traits are otherwise unknown in the genus.

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Hubungan Antara Sikap Terhadap Sistem Zonasi PPDB fan Motivasi Berprestasi Siswa SMPN 2 Wagir
Authors: Putri Arum Sekar Purwono , Hanurawan Fattah 
Published: April 2022

Abstract: The objectives of this study include: (1) to describe the attitudes of SMP 2 Wagir students towards the PPDB zoning system (2) to determine the description of the achievement motivation of SMPN 2 Wagir students regarding the implementation of the PPDB zoning system (3) to determine the relationship between attitudes towards the PPDB zoning system and achievement motivation in students of SMP 2 Wagir. This research uses a quantitative approach with descriptive correlational research. The population of this research is 546 students. The sampling technique used was random sampling so that the research subjects were 82 students at SMPN 2 Wagir. Subject data retrieval is done through the distribution of google forms. The instrument used was a scale of attitudes and a scale of achievement motivation with reliability of 0.849 and 0.910, respectively. The results showed that (a) students of SMPN 2 Wagir have a positive attitude towards the PPDB zoning system by 67 percent (b) SMP 2 Wagir students have high achievement motivation by 73 percent (c) there is a relationship between attitudes towards the PPDB zoning system and achievement motivation students of SMP 2 Wagir. The value obtained from the hypothesis test analysis is 0.644 with a significant level of 0.000.
Keywords: Attitudes towards the zoning system, achievement motivation, students of SMP 2 Wagir
Abstrak: Tujuan dari penelitian ini meliputi: (1) untuk mengetahui gambaran sikap siswa SMPN 2 Wagir terhadap sistem zonasi PPDB (2) untuk mengetahui gambaran motivasi berprestasi siswa SMPN 2 Wagir terkait penerapan sistem zonasi PPDB (3) untuk mengetahui hubungan antara sikap terhadap sistem zonasi PPDB dan motivasi berprestasi pada siswa SMPN 2 Wagir. Penelitian ini menggunakan pendekatan kuantitatif dengan jenis penelitian deskriptif korelasional. Populasi penelitian ini berjumlah 546 siswa. Teknik sampling yang digunakan yaitu random sampling sehingga didapatkan subjek penelitian sebanyak 82 siswa di SMPN 2 Wagir. Pengambilan data subjek dilakukan melalui penyebaran google form. Instrumen yang digunakan berupa skala sikap dan skala motivasi berprestasi dengan masing-masing reliabilitas 0,849 serta 0,910. Hasil penelitian menunjukkan bahwa (a) siswa SMPN 2 Wagir secara memiliki sikap terhadap sistem zonasi PPDB positif sebesar 67 persen (b) siswa SMPN 2 Wagir memiliki motivasi berprestasi tinggi sebesar 73 persen (c) terdapat hubungan antara sikap terhadap sistem zonasi PPDB dan motivasi berprestasi siswa SMPN 2 Wagir. Nilai yang didapatkan dari analisis uji hipotesis sebesar 0,644 dengan taraf signifikan sebesar 0,000.
Kata kunci: Sikap terhadap sistem zonasi, motivasi berprestasi, siswa SMPN 2 Wagir
ACCOUNTABILITY, TRANSPARENCY, COMPETENCE OF VILLAGE APPARATUS, AND INTERNAL CONTROL SYSTEM IN VILLAGE FINANCIAL MANAGEMENT
Authors: Cahyani Chairin Zhela , Basri Yesi Mutia , Kurnia Pipin 
Published: April 2022

This study aims to examine the effect of accountability, transparency, the competence of village officials, and internal control system on the village's financial management. The population in this study were all villages in Tandun and Ujung Batu areas, Rokan Hulu Regency. The sampling technique used in this research is saturated sampling. Saturated sampling was taken because all members of the population were used as samples. This study uses primary data through the distribution of questionnaires. Data analysis in this study used the Partial Least Square (PLS) approach with SmartPLS versionP3.0 computer software. The results of this study indicate that accountability affects village financial management, transparency affects village financial management, villages apparatus competence affects village financial management and the internal control system affects village financial management.
FRAUD ON GOVERNMENT: REVIEWED FROM ORGANIZATIONAL ETHICAL CULTURE, LEADERSHIP STYLE, AND LOVE OF MONEY
Authors: Fade Annisa Mutia Rama , Basri Yesi Mutia , Safitri Devi 
Published: April 2022

Fraud is actions and acts against the law that usually occur in an organization. The purpose of this study was to see how the influence of organizational ethical culture, leadership style, and love of money on fraud in Pekanbaru City Government ASN. The population in this study is the State Civil Apparatus (ASN) at the Pekanbaru City Government, as many as 7417 people. This study uses quantitative methods. The sampling technique used purposive sampling, with the characteristics of ASN who have a position and have work experience in a position of at least 1 year.The data collection technique used a questionnaire by distributing it directly to the Pekanbaru City Government OPD and also sending a questionnaire via google form. There were 207 questionnaires analyzed. The results of data analysis using WarpPLS 7.0 show that organizational ethical culture and leadership style have a negative effect on cheating in Pekanbaru City Government ASN, while love of money has a positive effect on fraud in Pekanbaru City Government ASN. The results of this study have a contribution to the government in efforts to reduce and prevent fraud, especially in the government sector.
Analisis Penyelesaian Pembiayaan Bermasalah di Masa Pandemi Covid-19 pada Koperasi Simpan Pinjam dan Pembiayaan Syariah Arrahmah
Authors: Riyantari Rani , Priyatno Prima Dwi 
Published: April 2022

Merebaknya coronavirus dan pemberlakuan pembatasan sosial berskala besar yang diterapkan di Indonesia menyebabkan banyak kinerja perusahaan mengalami penurunan, salah satunya pada koperasi simpan pinjam dan pembiayaan syariah. Dampak yang dihadapi koperasi yakni peningkatan nilai pembiayaan bermasalah akibat pandemi Covid-19. Artikel ini bertujuan untuk menganalisa strategi pengendalian yang dilakukan oleh koperasi untuk menekan tingkat pembiayaan bermasalah dengan mengacu Peraturan Pemerintah No. 7 dan Fatwa MUI No. 47, 48, dan 49. Metode artikel ini memakai pendekatan kualitatif deskriptif dengan jenis studi kasus. Pengumpulan data yang digunakan adalah dengan teknik wawancara terstruktur, observasi partisipan pasif, dan dokumentasi. Peneliti menggunakan teknik triangulasi untuk menguji validitas data, dan peneliti melakukan teknik analisa data. Hasil penelitian dapat disimpulkan peningkatan tingkat non-performing financing disebabkan oleh faktor internal dan eksternal yang masing-masing bersumber dari koperasi dan anggota koperasi. Peneliti menemukan bahwa terdapat strategi pengendalian sesuai dengan Peraturan Pemerintah dan Fatwa MUI antara lain konsolidasi, optimalisasi sistem penagihan dan monitoring, revitalisasi proses melalui restrukturisasi dan rescheduling, collacteral, dan write-off.Kata kunci: Covid-19, KSPPS, NPF, strategi pengendalian
Understanding Musculoskeletal Disorders Through Next-Generation Sequencing
Authors: Garg Bhavuk , Tomar Neeraj , Biswas Amitabh , Mehta Nishank , Malhotra Rajesh 
Published: April 2022

» An insight into musculoskeletal disorders through advancements in next-generation sequencing (NGS) promises to maximize benefits and improve outcomes through improved genetic diagnosis.» The primary use of whole exome sequencing (WES) for musculoskeletal disorders is to identify functionally relevant variants.» The current evidence has shown the superiority of NGS over conventional genotyping for identifying novel and rare genetic variants in patients with musculoskeletal disorders, due to its high throughput and low cost.» Genes identified in patients with scoliosis, osteoporosis, osteoarthritis, and osteogenesis imperfecta using NGS technologies are listed for further reference.
Deoiling Hydrocyclones: An Experimental Study of Novel Control Schemes
Authors: Mishiga Vallabhan K G , Holden Christian , Skogestad Sigurd 
Published: April 2022

Summary
Deoiling hydrocyclones are compact, passive devices commonly used for produced-water treatment (PWT) for oil production. The oily water enters the tangential inlet of the hydrocyclone and gets separated such that cleaned water comes out as a water-reject (underflow) stream, and concentrated oil comes out as an oil-reject (overflow) stream. For control purposes, the pressure drop ratio (PDR) across the inlet and the two outlets may be kept constant to maintain separation in the presence of disturbances. However, the PDR control scheme does not effectively reject some disturbances, such as changes in the inlet oil concentration and inlet droplet distribution. This paper proposes three novel control schemes to improve the separation with the aim to limit the oil concentration at the water reject at 30 ppm. The control schemes use concentration measurements from online oil-in-water analyzers at the inlet and water-reject (underflow) outlet. Two control schemes (a feedforward and a feedback/cascade) are used as a supervisory layer to the existing PDR control scheme. The third control scheme directly manipulates the final control element (valve position) to maintain the separation of the hydrocyclones. This paper gives experimental results to validate all three control schemes when subjected to disturbances such as changes in inflow rate, inlet oil concentration, and inlet droplet distribution.
Design of and Outcomes in a Student-Run Free Mental Health Clinic Serving the Uninsured in East Harlem
Authors: Powell Samuel K , Saali Alexandra , Frere Justin , Magill Elizabeth , Krystal Hannah , Serafini Randal , Sultana Syeda , Dale Brandon , Ali Muhammad , Kumar Vedika , Datta Debjyoti , Hernandez-Antonio Josimar , Aronson Anne , Meah Yasmin , Gluhoski Vicki , Katz Craig 
Published: April 2022

Abstract
Background
Safety-net clinics are an important source of low-cost or free mental healthcare to those with limited financial resources. Such clinics are often staffed by trainees in early stages of their career. Only limited data exists on best practices in treatment-implementation and on clinical outcomes attained in such clinics. The primary purpose of this article is to describe the design of a student-run free mental health clinic serving uninsured individuals in New York City’s East Harlem neighborhood and to analyze the quality of services provided and the clinical outcomes attained.
Methods
The authors conducted a retrospective chart review of n=69 patients treated in the EHHOP Mental Health Clinic (E-MHC). Utilizing Health Effectiveness Data and Information Service metrics, they estimated the likelihoods of patients meeting metric quality criteria compared to those in other New York State (NYS) insurance groups. The authors derived linear mixed effect and logistic regression models to ascertain factors associated with clinical outcomes. Finally, the authors report on feedback provided by the patients collected via a customized survey.
Results
The clinical service performance of the E-MHC was non-inferior on most measures examined. The E-MHC underperformed NYS HMO clinics in the provision of acute-phase antidepressant medication management; the authors did not find any performance differences in continuation-phase antidepressant management. Additionally, the E-MHC outperformed NYS commercial and Medicaid plans on optimal provider contacts for depression and follow-up care after ED visit for alcohol or other drugs within 30 days. Factors associated with symptom improvement were number of treatment sessions and certain demographic and clinical variables. Patients provided highly positive feedback on the care they received.
Conclusions
SRFCs can provide quality care to vulnerable patients that leads to clinically meaningful reductions in psychiatric symptoms and is well-received by patients.
JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE
Authors: Zhong Xiaolin , Chen Zuyao , Wang Yajuan , Mao Mingli , Deng Yingcheng , Shi Mengmeng , Xu Yang , Chen Ling , Cao Wenyu 
Published: April 2022

Abstract
Sepsis-associated encephalopathy (SAE) manifests clinically in hyperneuroinflammation. Pyroptosis, which can induce an inflammatory cascade response, has been considered to be a causative factor of SAE. Evidence has shown that the bromo- and extraterminal (BET) proteins (including BRD2, BRD3, BRD4 and BRDT) inhibitor JQ1 can inhibit inflammation and suppress pyroptosis in various diseases. Therefore, we examined the effect of JQ1 on inflammasome-induced pyroptosis in the hippocampus in a mouse model of sepsis induced by lipopolysaccharide (LPS) injection. The results showed that JQ1 treatment alleviated sepsis-related symptoms, protected the blood–brain barrier (BBB), as indicated by upregulated expression of the tight junction proteins occludin and ZO-1, and remarkably rescued neuronal damage in SAE mice. Mechanistically, we demonstrated that JQ1 intervention inhibited the expression of BRD proteins and decreased the expression of inflammasomes by blocking nuclear factor kappa B (NFκB) signalling, attenuating the canonical pyroptosis (mediated by cleaved-Caspase1/11) pathway and the release of proinflammatory factors in the hippocampus of septic mice. Interestingly, we also found that JQ1 selectively suppressed the activation of hippocampal microglia in SAE mice. Thus, JQ1 protected the hippocampal BBB and neuronal damage through the attenuation of neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway induced by LPS injection in mice, and JQ1 may be a promising target for the prevention of SAE.
Placental DNA methylation changes in the development of gestational diabetes mellitus
Authors: Chen Fujia , Li Min , Fei Xiaoping , Zhu Weiqiang , Zhang Zhaofeng , Shen Yupei , Mao Yanyan , Zhu Qianxi , Xu Jianhua , Zhou Weijin , Du Jing 
Published: April 2022

Abstract
Aims
The aim of this study was to investigate the association between gene methylation alterations and the development of GDM, as well as to investigate the potential epigenetic mechanisms of GDM.
Methods
Reduced representation bisulfite sequencing (RRBS) and RNA sequencing (RNA-seq) analysis were performed on placental tissues from women with GDM and healthy controls. After pyrosequencing, correlation and linear regression analysis were applied based on the effect of methylated-differentially expressed genes (DEGs).
Results
HOXD9, ALDH1A2, CSMD1, TRIM67, and PAX8, five candidate DEGs, were identified. TRIM67 exhibited significant hypermethylation levels at different CpG sites. Hypermethylation of TRIM67 promoter was significantly positively correlated with 1h and 2h OGTT glucose levels and negatively correlated with Lipoprotein(a).
Conclusions
TRIM67 hypermethylation in the placenta of women with GDM may correlate with insulin resistance, which may play a role in the development of GDM. These findings provide new insights for further studies on the pathophysiology of GDM.
Cutaneous fistula, a rare presentation of squamous cell carcinoma of the renal pelvis
Authors: abdelkader abdelrahman 
Published: April 2022

Abstract
Background : Renal cell carcinoma with all its variants represent more than ninety percent, the remaining ten percent is divided on urothelial tumors, sarcomas and metastasis from other organs. Squamous cell carcinoma of the renal pelvis is mentioned very few due to its rarity. Until now there is no guideline for managing it unlike transitional cell carcinoma. Our case is very rare, one or two case all over the world has been reported to our knowledge, also the treatment plan which was salvage surgery was very successful. Case presentation: This article will discuss a male patient who developed squamous cell carcinoma in the renal bed after nephrectomy, managed with excellent outcome in Assiut university hospital. After 8 month the patient show good and excellent performance. Conclusions : The general rule of this type of malignancy is that it is resistant to both chemo and radiotherapy with good outcome to surgery if early intervention was done. Our case could provide a beacon for similar cases.
Nursing assistant’s knowledge, attitude and training demands toward urinary incontinence in nursing homes: A mixed methods study
Authors: Liao Lulu , Jiao Jingjing , Zhao Yinan , Ning Hongting , Feng Hui 
Published: April 2022

Abstract
Background: Urinary incontinence is an increasingly common problem, especially the older people. Nursing assistants are the main force in nursing homes. Their knowledge and attitude about urinary incontinence is attracting considerable critical attention. However, most previous studies have focused on nurses in hospital. This study set out to figure out the nursing assistants’ training needs concerning urinary incontinence.Methods：We conducted a two-part mixed-methods study. A survey on the knowledge and attitude of nursing assistants about urinary incontinence was undertaken (n=509). Then, semi-structured interviews were used to elicit detail training demands (n=40). Results：In general, urinary incontinence knowledge was poor (14±4.18), while attitudes were mostly positive (35.51±3.19). The nursing assistants are very interested in learning more about urinary incontinence. The variety of preferred learning methods emphasizes the need for diversified educational materials.Conclusions：Urinary incontinence is an effective indicator of care quality in nursing homes. The managers should formulate targeted training courses and preferred training forms suitable for the nursing homes.
Prevalence of Psychological Khat Dependency and It’s Associated Factors Among Mettu University Students, Southwest Ethiopia, 2021
Authors: Efrem Mesfin , Mulat Haregewoyn , Kassew Tilahun , Minichil Woredawu 
Published: April 2022

Abstract
Introduction: It is estimated that 5 to 10 million people worldwide chew Khat, the majority of whom live in the Horn of Africa and the Arabian Peninsula, particularly Ethiopia, Somalia, and Yemen. Chewing khat is a part of life for a vast majority of the people in these countries. Excessive and long-term khat use has the potential to cause psychological dependency with a prominent feature akin to amphetamine-type stimulant dependence. The goal of this study was to determine the prevalence of psychological khat addiction and the factors that contribute to it among Mettu University students. Methods: institution based cross-sectional study was conducted from April 01/2021 – April 29/,2021at Mettu University. The study sample was recruited through Stratified multistage sampling technique (n = 1046). Structured English version self-administered questionnaire were used to collect data on socio-demographic factors, habit of khat use and other variables. The data were edited, cleaned, coded and entered in to Epi-data version 4.6.02 then it was exported to Stata/SE 14.0. Binary and multivariable logistic regressions were used to identify sociodemographic factors and other substance-use related factors that are associated with psychological khat dependency. Results were interpreted and presented in the form of table, figures & chart. Result: Among the original 1046 participants 1001 of them were clearly fill and respond the questionnaire but only157 of current khat chewer were included in the analysis process since the target of the study was to study dependency on khat. The results of the other 1001 respondents were simply reported descriptively through table and diagram. Among 157 current khat chewers 47.7% (95% CI: 39.9–55.6) of them were found dependent on khat based on SDS score whether the left 52.23% respondents were not khat dependent. Among those found dependent the amount of khat chewed each session (AOR; =6.72, 95% CI’ =2.17–20.78), duration of chewing khat in each session (AOR; =4.2, 95% CI; =1.43–12.73), days chewing khat per week (AOR; =4.2, 95% CI; =1.39–12.96), depression (AOR; =4.08, 95% CI; =1.40–11.9), cigarrete smoking (AOR; =3.5, 95% CI; =1.0032–12.37), poor social support (AOR; =4.4, 95% CI; =1.34–14.43) and 4th year and above (AOR; =3.65, 95% CI; =1.07–12.49) were show significance association with khat dependency both in bivariate and multivariate analysis. Conclusion: khat chewing has a psychological dependence effect on those who use khat for prolonged time, chewing large amount of khat and those who chew khat frequently, Therefore, it calls for a strong multi sectorial involvement including local administrative bodies, health services providers, and non-governmental organizations.