bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crossing the Finish Line but Losing the Race? Socioeconomic Inequalities in the Labor Market Trajectories of Community College Graduates
Authors: Kim Brian Heseung , Bird Kelli A. , Castleman Benjamin L. 
Published: October 2022

Abstract
Despite decades and hundreds of billions of dollars of federal and state investment in policies to promote postsecondary educational attainment as a key lever for increasing the economic mobility of lower income populations, research continues to show large and meaningful differences in the mid-career earnings of students from families in the bottom and top income quintiles. Prior research has not disentangled whether these disparities are due to differential sorting into colleges and majors, or due to barriers that lower socioeconomic status (SES) graduates encounter during the college-to-career transition. Using linked individual-level higher education and Unemployment Insurance records for nearly a decade of students from the Virginia Community College System, we compare the labor market outcomes of higher and lower SES community college graduates within the same college, program, and academic performance level. Our analyses show that, conditional on employment, lower SES graduates earn nearly $500/quarter less than their higher SES peers one year after graduation, relative to higher SES graduate average of $10,846/quarter. The magnitude of this disparity persists through at least three years after graduation. Disparities are concentrated among non-nursing programs, in which gaps persist seven years from graduation. Our results highlight the importance of greater focus on the college-to-career transition.
Stress and Cognitive Performance: Evidence from a South Korean Earthquake
Authors: Cho Hyunkuk , Kim Hwanyeon 
Published: October 2022

Abstract
Studies have identified negative effects of cortisol, a stress hormone, on academic performance. Because natural disasters induce community-wide stress, students who experience natural disasters may subsequently perform worse academically. Our study is the first to examine the immediate effects of close exposure to a natural disaster on academic performance. We examine the impact of the 2017 Pohang earthquake in South Korea on college entrance exam scores. The 5.4 magnitude quake occurred one day before the scheduled nationwide college entrance exam date, necessitating its postponement for one week. Several aftershocks occurred during that postponement period. We find that the earthquake decreased the reading test scores of students in the Pohang area by 0.05 standard deviation but had no effect on math test scores. The reading test was administered earlier in the day than the math test, so these findings suggest that students taking exams in post-traumatic situations might be able to perform better after a warm-up testing period. Finally, male students suffered the largest adverse impacts on their reading test scores, with serious implications given the high-stakes nature of the exams.
Bayesian Optimization for Cascade-Type Multistage Processes
Authors: Kusakawa Shunya , Takeno Shion , Inatsu Yu , Kutsukake Kentaro , Iwazaki Shogo , Nakano Takashi , Ujihara Toru , Karasuyama Masayuki , Takeuchi Ichiro 
Published: October 2022

Abstract
Complex processes in science and engineering are often formulated as multistage decision-making problems. In this letter, we consider a cascade process, a type of multistage decision-making process. This is a multistage process in which the output of one stage is used as an input for the subsequent stage. When the cost of each stage is expensive, it is difficult to search for the optimal controllable parameters for each stage exhaustively. To address this problem, we formulate the optimization of the cascade process as an extension of the Bayesian optimization framework and propose two types of acquisition functions based on credible intervals and expected improvement. We investigate the theoretical properties of the proposed acquisition functions and demonstrate their effectiveness through numerical experiments. In addition, we consider suspension setting, an extension in which we are allowed to suspend the cascade process at the middle of the multistage decision-making process that often arises in practical problems. We apply the proposed method in a test problem involving a solar cell simulator, the motivation for this study.
Translation of nurse-initiated protocols to manage fever, hyperglycaemia and swallowing following stroke across Europe (QASC Europe): A pre-test/post-test implementation study
Authors: Middleton Sandy , Dale Simeon , McElduff Benjamin , Coughlan Kelly , McInnes Elizabeth , Mikulik Robert , Fischer Thomas , Van der Merwe Jan , Cadilhac Dominique , D’Este Catherine , Levi Christopher , Grimshaw Jeremy M , Grecu Andreea , Quinn Clare , Cheung Ngai Wah , Koláčná Tereza , Medukhanova Sabina , Sanjuan Menendez Estela , Salselas Susana , Messchendorp Gert , Cassier-Woidasky Anne-Kathrin , Skrzypek-Czerko Marcelina , Slavat-Plana Merce , Antonella Urso , Pfeilschifter Waltraud 
Published: October 2022

Introduction: Poor adoption of stroke guidelines is a problem internationally. The Quality in Acute Stroke Care (QASC) trial demonstrated significant reduction in death and disability with facilitated implementation of nurse-initiated protocols to manage fever, hyperglycaemia and swallowing (FeSS Protocols) following stroke. We aimed to determine real-world effectiveness of supported implementation of the FeSS Protocols across Europe. Methods: This was a multi-country, multi-centre, pre-test/post-test study (2017–2021) comparing post implementation data with historically collected pre-implementation data. Hospital clinical champions, supported by the Angels Initiative conducted multidisciplinary workshops discussing pre-implementation medical record audit results, barriers and facilitators to FeSS Protocol implementation, developed action plans and provided education, with ongoing support co-ordinated remotely from Australia. Prospective audits were conducted 3-month after FeSS Protocol introduction. Pre-to-post analysis and country income classification comparisons were adjusted for clustering by hospital and country controlling for age/sex/stroke severity. Results: Data from 64 hospitals in 17 countries (3464 patients pre-implementation and 3257 patients post-implementation) showed improvement pre-to-post implementation in measurement recording of all three FeSS components, all p < 0.0001: fever elements (pre: 17%, post: 51%; absolute difference 33%, 95% CI 30%, 37%); hyperglycaemia elements (pre: 18%, post: 52%; absolute difference 34%; 95% CI 31%, 36%); swallowing elements (pre: 39%, post: 67%; absolute difference 29%, 95% CI 26%, 31%) and thus in overall FeSS Protocol adherence (pre: 3.4%, post: 35%; absolute difference 33%, 95% CI 24%, 42%). In exploratory analysis of FeSS adherence by countries’ economic status, high-income versus middle-income countries improved to a comparable extent. Discussion and conclusion: Our collaboration resulted in successful rapid implementation and scale-up of FeSS Protocols into countries with vastly different healthcare systems.
Osteochondritis Dissecans of the Talus: A New Transmalleolar Fixation Technique
Authors: Moisan Philippe , Lamer Stéphanie , Li Orville , Grimard Guy , Nault Marie-Lyne 
Published: October 2022

Background: Conservative management is the first line of treatment in most osteochondritis dissecans (OCD) cases and can be sufficient for small and stable lesions in skeletally immature patients. Unstable lesions commonly require surgical interventions and may need fixation. The standard surgical approach to fix posteromedial lesions of the talus involves an osteotomy of the medial malleolus. This technique is invasive and requires multiple weeks of immobilization after the surgery. In this video, we present a minimally invasive transmalleolar approach used for the fixation of an OCD lesion of the talus. Indications: The main indication for this procedure is the failure of conservative management with persistent ankle pain and functional impairment of an unstable osteochondral lesion with poor potential for revascularization. Technique Description: There are 3 key steps to this surgery: ankle arthroscopy, retroarticular drilling, and transmalleolar fixation. The transmalleolar approach is achieved by creating a tunnel through the medial malleoli oriented toward the lesion. To do so, the surgeon combines fluoroscopy and ankle arthroscopy to first insert a Kirschner wire (K-wire) through the medial malleoli. Once the correct orientation is confirmed, a 4.5-mm cannulated drill bit is used to create the tunnel. Arthroscopic visualization is used to avoid iatrogenic cartilage damage during drilling. Once the tunnel is created, ankle dorsiflexion and plantar flexion are used to access the entire lesion and insert screws. The malleolar tunnel is then filled with a bone graft and the wound closed. The patient is immobilized for 2 weeks after which gentle range of motion is initiated. The patient remains non-weight-bearing for 2 months and is then allowed to bear weight using a boot. Results: Transmalleolar fixation for osteochondritis dissecans of the talus is a minimally invasive procedure that does not require an osteotomy of the medial talus. This approach permits early postoperative range of motion and decreases postoperative pain and edema, but the adequate positioning of the tunnel can prove challenging. Conclusion: Transmalleolar approach to the talus is minimally invasive and allows adequate fixation of certain osteochondral lesions. Studies comparing the reoperation and complication rate with the standard malleolar osteotomy are lacking and need to be performed. The author(s) attests that consent has been obtained from any patient(s) appearing in this publication. If the individual may be identifiable, the author(s) has included a statement of release or other written form of approval from the patient(s) with this submission for publication.
Multi-omics reveals the key and specific miRNA-mRNA modules underlying salt tolerance in wild emmer wheat (Triticum dicoccoides L.)
Authors: Yang Guang , Pan Wenqiu , Cao Rui , Guo Qifan , Cheng Yue , Zhao Qinlong , Cui Licao , Nie Xiaojun 
Published: October 2022

Abstract
Background
Salt stress is one of the most destructive environmental factors limiting crop growth and development. MicroRNAs (miRNAs) are a class of conserved endogenous small non-coding RNAs, playing the crucial role in regulating salt response and tolerance in plants. However, the miRNAs in wild emmer wheat, especially the key and specific salt-responsive miRNAs are not well studied.

Results
Here, we performed small RNA, transcriptome, and degradome sequencing of both of salt-tolerance (ST) and salt-sensitive (SS) wild emmer genotypes to identify the miRNA-mRNA modules associating with salt tolerance. Totally, 775 miRNAs, including 361 conserved known miRNAs and 414 novel miRNAs were detected. Differential expression analysis identified 93 salt-responsive miRNAs under salt stress. Combined with RNA-seq and degradome sequencing analysis, 224 miRNA-mRNA modules displayed the complete opposite expression trends between ST and SS genotypes, most of which functionally enriched into ROS homeostasis maintaining, osmotic pressure modulating, and root growth and development. Finally, the qRT-PCR and a large-scale yeast functional screening were also performed to initially validate the expression pattern and function of candidate genes.

Conclusions
This study reported the key and specific miRNA-mRNA modules associated with salt tolerance in wild emmer, which lay the foundation for improving the salt tolerance in cultivated emmer and bread wheat through miRNA engineering approach.
Serum apolipoprotein A-IV levels are associated with flow-mediated dilation in patients with type 2 diabetes mellitus
Authors: Li Le-Ying , Chen Shuai , Wang Yi-Xuan , Ji Ri , Ding Feng-Hua , Wang Xiao-Qun , Chen Qiu-Jing , Lu Lin , Dai Yang 
Published: October 2022

Abstract
Background
Endothelial dysfunction is common in diabetes. Apolipoprotein (apo) A-IV functions to antagonize inflammation and oxidative stress. The present study aimed to investigate the relationship between flow-mediated dilation (FMD) and serum apoA-IV level in type 2 diabetes mellitus (T2DM) patients.

Methods
A total of 84 T2DM patients with chest discomfort were enrolled in this study. Their baseline characteristics and clinical parameters were documented. Endothelial function of the participants was evaluated by examining FMD of brachial artery. The severity of coronary atherosclerosis was determined by quantitative coronary angiography. Serum apoA-IV levels were measured by ELISA.

Results
These diabetic patients were dichotomized into low FMD (n = 42) and high FMD (n = 42) groups. Serum apoA-IV levels were significantly higher in high FMD group than in low FMD group (29.96 ± 13.17 vs 17.69 ± 9.16 mg/dL, P < 0.001). Moreover, the patients were also categorized into three apoA-IV tertile groups. FMD was significantly different across three apoA-IV tertiles (P < 0.001). Serum apoA-IV levels were positively correlated to FMD (r = 0.469, P < 0.001). Logistic regression analysis was performed to determine risk factors for low FMD. apoA-IV levels together with the risk factor hsCRP remained significantly to be independent determinants of low FMD (P < 0.01). Linear regression analysis was performed, and apoA-IV levels together with total-to-HDL cholesterol ratio were independently correlated with FMD (P < 0.01).

Conclusions
Serum apoA-IV levels are associated with FMD, suggesting that apoA-IV protects endothelial function in patients with T2DM.
How to fall into a new routine: factors influencing the implementation of an admission and discharge programme in hospitals and general practices
Authors: Forstner Johanna , Litke Nicola , Weis Aline , Straßner Cornelia , Szecsenyi Joachim , Wensing Michel 
Published: October 2022

AbstractIntroductionThe VESPEERA programme is a multifaceted programme to enhance information transfer between general practice and hospital across the process of hospital admission, stay and discharge. It was implemented in 7 hospitals and 72 general practices in Southern Germany. Uptake was heterogeneous and overall low. A process evaluation aimed at identifying factors associated with the implementation of the VESPEERA programme.MethodsThis was a qualitative study using semi-structured interviews in a purposeful sample of health workers in hospitals and general practices in the VESPEERA programme. Qualitative framework analysis using the Consolidated Framework for Implementation Research was performed and revealed the topic of previous and new routines to be protruding. Inductive content analysis was used for in-depth examination of stages in the process of staying in a previous or falling into a new routines.ResultsThirty-six interviews were conducted with 17 participants from general practices and 19 participants from hospitals. The interviewees were in different stages of the implementation process at the time of the interviews. Four stages were identified: Stage 1,’Previous routine and tension for change’, describes the situation in which VESPEERA was to be implemented and the factors leading to the decision to participate. In stage 2,’Adoption of the VESPEERA programme’, factors that influenced whether individuals decided to employ the innovation are relevant. Stage 3 comprises ‘Determinants for falling into and staying in the new VESPEERA-routine’ relates to actual implementation and finally, in stage 4, the participants reflect on the success of the implementation.ConclusionsThe individuals and organisations participating in the VESPEERA programme were in different stages of a process from the previous to the new routine, which were characterised by different determinants of implementation. In all stages, organisational factors were main determinants of implementation, but different factors emerged in different implementation stages. A low distinction between decision-making power and executive, as well as available resources, were beneficial for the implementation of the innovation.Trial registrationDRKS00015183 on DRKS / Universal Trial Number (UTN): U1111-1218–0992.
Comments on the paper “Best proximity point results with their consequences and applications”
Authors: Som Sumit , Gabeleh Moosa 
Published: October 2022

AbstractVery recently Jain et al. (J. Inequal. Appl. 2022:73, 2022) introduced the concept of multivalued F-contraction with altering distance function and investigated the existence of best proximity points for this class of mappings. In this article we prove that the existence of best proximity points for multivalued F-contraction non-self mappings can be obtained from the corresponding fixed point result for multivalued F-contraction self mappings, and so the main conclusion due to Jain et al. is not a real generalization of fixed point theory.
Evaluation of the use of autologous platelet-rich fibrin in myringoplasty operation
Authors: Aboelnaga Heba Abdelreheem , Elsharnouby Mohammed Kamar , Ali Ayman Ali Abdelfattah , Elkamshishi Tamer Aboelyazeed , Abdelhafez Tarek Abdelrahman 
Published: October 2022

Abstract
Background
Platelet-rich fibrin (PRF) which is considered a second-generation platelet-rich plasma having a high content of growth factors could be implied as a sealant and adjuvant to grafting materials during tympanoplasty operation. This work aimed to evaluate the role of autologous platelet-rich fibrin as an adjuvant in type 1 tympanoplasty (myringoplasty) for the closure of central tympanic membrane perforations. A prospective comparative study was conducted including one-hundred patients with chronic suppurative otitis media with dry central TM perforations. The patients were classified into two equal groups: group A (case group) was subjected to myringoplasty operation with the use of autologous PRF added to the temporalis fascia graft, and group B (control group) was subjected to myringoplasty operation using graft only without PRF. Both groups were assessed for successful closure of perforation defined as an intact eardrum, success in terms of hearing defined as closure of air-bone gap down to 10 dB or lesser, and hearing gain at 6 months postoperatively.

Results
At 6 months postoperatively, the success rate (graft taking) in group A (90%) was significantly higher than in group B (70%). Success in terms of air-bone gap closure (< 10 dB) revealed that in group A, success was achieved in 39 patients (78%), which was significantly higher than in group B 27 patients (54 %). Air-bone gap at 6 months postoperatively was more in the graft taken cases in the case group than in the control group with a significant difference. There was a nonsignificant correlation between graft uptake and either hemoglobin or platelet concentrations in both groups. In addition, there was a nonsignificant correlation between graft uptake and the size of the perforation in both groups.

Conclusion
Platelet-rich fibrin is a cheap, cost-effective, and completely autologous platelet concentrate with enriched growth factors. It improves the overall success rate of myringoplasty with no noticeable side effects.
Endoscopic-assisted approaches for enucleation of invaded sinonasal region by benign odontogenic cysts: a case series study
Authors: Ragab Ahmed A. , Abo El Naga Heba Abdel Rahem 
Published: October 2022

Abstract
Background
During surgical planning for the excision of odontogenic cysts and tumors, surgeons should consider choosing the appropriate endoscopic approach to reach all parts of the maxillary sinus and cyst walls during its enucleation. Using the endoscopic trans-nasal approaches results in less than one-third of the maxillary sinus being reached regardless of antrostomy or angled instruments used. Also, the expansion process and involvement of maxillary sinuses in odontogenic cysts and tumors are variable, adding more difficulties during excision. This study aimed to assess the expansion process of large benign odontogenic cysts and tumors involving nasoantral regions and adaptability to different endoscopic approaches for enucleation. Six patients were included in this case series study. Preoperative panoramic views plain film radiography, and computed tomography scans were obtained. Lesion characteristics, relation to teeth origin, the nose, and maxillary sinus wall displacement, location of lesions about typical vertical and horizontal nasomaxillary constructions, and associated inflammation of the paranasal sinuses were evaluated. Three surgical approaches were tailored, allowing viewing and endoscopic enucleation.

Results
Four periapical (radicular) cysts, one ameloblastoma, and one calcifying epithelial odontogenic tumor, ranging in size from 3 to 5 cm, were enucleated endoscopically in patients aged 15–40 years. Intra-sinus expansion of the cyst and lesion level above the nasal floor allowed endoscopic enucleation using wide middle meatal antrostomy in 1 (17%). Lesions localized to the anterior wall and the nasal process of the maxilla permitted endonasal minimal rhinotomy approach in 1 (17%). Central lesions, cyst extension below the level of the nasal floor, and lateral wall expansion with or without anterior maxillary wall scalloping had adequate exposure using a minimal sublabial approach in four patients (67%). Together with its role in complete enucleation, endoscopy allowed associated rhinosinusitis surgical treatment in five patients (83%).

Conclusion
Tailoring surgical approaches to the expansion process allowed endoscopic enucleation of large odontogenic cysts/tumors without wall remnants. The integrity of the Schneiderian membrane was preserved, protecting the critical surrounding structures.
In vitro evaluation of ruminal digestibility and fermentation characteristics of local feedstuff-based beef cattle ration
Authors: Mayulu Hamdi , Daru Taufan Purwakusumaning , Tricahyadinata Irsan 
Published: October 2022

Background: Consumption of local feedstuff Neptunia plena L. Benth and Leersia hexandra Swartz as a ration by the animal subject is expected to promote cost efficiency and production, as well as provide essential nutrition needs. Therefore, this study aimed to evaluate dry matter digestibility (DMD), organic matter digestibility (OMD), ammonia (NH3) production, and volatile fatty acid (VFA) in beef cattle. Methods: Feed and rumen inoculum samples were prepared and analyzed for their proximate contents. There were five treatment groups based on the diet received by beef cattle, namely: T1 (Leersia hexandra Swartz 100 %); T2 (Neptunia plena L. Benth 100%); T3 (Leersia hexandra Swartz 15% + (Neptunia plena L. Benth 15% + 70 % Other Feedstuffs); T4 (Leersia hexandra Swartz 20% + (Neptunia plena L. Benth 20% + 60% Other Feedstuffs); T5 (Leersia hexandra Swartz 25% + (Neptunia plena L. Benth 25% + 50% Other Feedstuffs). In vitro approaches were used to determine the DMD, OMD, NH3 production, and VFA in beef cattle. The data were analyzed using ANOVA at a significance level of 95%, and a Duncan Multiple Range Test. Results: The results showed that the highest DMD (P<0.05) was derived from T 5 (56.47%), followed by T 4 (56.45%) and T 3 (55.90%). T 5=62.40% significantly (P<0.05) generated the highest OMD followed by T 4=61.95% and T 3=60.82%. This treatment had the highest NH 3 value, namely 5.02 mM, compared with T 3=4.55 mM, T 4=4.50 mM, T 2=4.22 mM, and T 1=3.99 mM. Furthermore, T5 had the highest VFA (P<0.05) compared with T 4, T 3, T 2, and T 1 with the value of 150.5, 133.0, 130.5, 130.0, and 123.5 mM, respectively. Conclusions: The local feedstuff-based ration contributed to beef cattle production.