bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incision-based Blepharoplasty with Preservation of Superficial and Deep Blood Vessels
Authors: Jiafu Yang , Hong Ji , Chen Zhang , Zhijun Wang , Zhigang Liu 
Published: October 2022

Background:
Single eyelids of many individuals seek incision-based blepharoplasty to construct double eyelids. However, excessive tissue damage is still a common problem after this surgery. Much of the tissue injury incurred during blepharoplasty results from damage to vertical blood vessels in the superficial and deep layers, so we designed a new modified incisional-based blepharoplasty method that preserves superficial and deep blood vessels.

Purpose:
To evaluate the efficacy and safety of this preservation of superficial and deep blood vessels approach to incisional-based blepharoplasty.

Methods:
We retrospectively examined the outcomes of 462 consecutive patients receiving this new method from January 2015 to December 2019. The surgical methods were designed to preserve superficial and deep blood vessels to the greatest extent possible. All patients were followed up for 6 to 40 months. Postoperative evaluations were performed and patients graded results at final follow-up as excellent, good, fair, or poor. The combined proportion of excellent, good, and fair was deemed the satisfaction rate.

Results:
The overall satisfaction rate was 94.16% (435/462). Postoperative swelling regressed significantly during the first week and disappeared by 4 weeks postsurgery for patients without ptosis or with mild ptosis, whereas swelling regressed in 2 to 5 weeks for patients with moderate ptosis. Fourteen patients (3.03%, 14/462) displayed obvious bruising after surgery.

Conclusions:
This new blepharoplasty method yielded a high satisfaction rate, rapid dissipation of swelling, low bruising, and low complication rate. This effective and safe surgical method warrants wider use for single eyelid and mild/moderate ptosis.
Perioperative Risk Factors Associated With Unplanned Reoperation Following Vascularized Free Flaps Reconstruction of the Oral Squamous Cell Carcinoma
Authors: Fu Ganglan , Wang Chengli , Zeng Chengbo , Liu Zhongqi , Han Zhixiao , Huang Haoquan , Cao Minghui 
Published: October 2022

Objectives:
To find out the occurrence rate and risk factors of unplanned reoperation (any unscheduled surgery within 30 d after the initial surgery) in patients who have received oral squamous cell carcinoma (OSCC) surgery and vascularized free flap reconstruction.

Patients and Methods:
We organized a retrospective study of 1058 patients who underwent OSCC resection and reconstruction with vascularized free flaps from 2011 to 2019. Clinical characteristics, reasons for unplanned reoperation, flap types, and previous treatment were compared between the unplanned reoperation group and the control group. Univariate and multivariate analyses were performed to identify perioperative risk factors for unplanned reoperation. The related perioperative factors that may influence perioperative infusion were included in propensity score matching to investigate the independent contribution of intraoperative colloid infusion on unplanned reoperation.

Results:
The overall rate of unplanned reoperation in OSCC patients was 11% (n=115). Flap necrosis and bleeding were the most common causes. Higher American Society of Anesthesiologists (ASA) grade [odds ratio (OR)=1.709, P=0.009], postoperative anemia (OR=0.983, P=0.011) and excessive intraoperative colloid input (OR=1.55, P=0.037) were identified as risk factors for unplanned reoperation. Propensity score matching was applied, and the difference of unplanned reoperation incidence between the matched groups was statistically significant (14.59% versus 8.54%; P=0.025). The multivariate analyses after propensity score matching confirmed that the intraoperative rate of colloid infusion of more than 2.3 mL/kg/h (OR=1.756, P=0.042) and prior radiotherapy (OR=2.78, P=0.001) are independent risk factors for unplanned reoperation.

Conclusion:
High intraoperative colloid infusion rate and prior radiotherapy may increase the risk of unplanned reoperation in patients who underwent OSCC surgery and vascularized free flap reconstruction.
Analysis of Inferior Nasal Morphology and Nostrils following Le Fort I Osteotomy
Authors: Suzen Muazzez , Dilaver Emrah , Ak Kivanc Berke , Uckan Sina 
Published: October 2022

Objective:
This study aimed to investigate the soft tissue parameters related to inferior nasal morphology and nostril shape and investigate the change at nostril types according to the Modified Topinard System following maxillary surgery.

Materials and Methods:
Thirty-five patients who underwent Le Fort I osteotomy with or without mandibular osteotomy were included in this retrospective study. Presurgery (T1) and postsurgery (T2) measurements which were the angle between the longitudinal axis of left and right nostril, nostril length, nostril width, alar width, alar base width, columella length, and columella width, were measured on computed tomography images. Nostril types according to Modified Topinard System and nostril shapes were also examined.

Results:
Following Le Fort I surgery, there was a significant increase in alar base width, alar width, and angle between the longitudinal axis of the left and right nostril (P<0.05). Nasal tip protrusion was decreased with significance (P=0.022). Multiple linear regression analysis showed that every 1 mm maxillary impaction amount leads to a 3.34° increase in the angle between the longitudinal axis of the left and right nostrils (P=0.03, adjusted R
2=0.21). Nostril type classification according to Modified Topinard System was changed significantly (P=0.000).

Conclusion:
Surgeons should be aware of the risk of postoperative nonaesthetic results in Modified Topinard System’s borderline cases. Modified Topinard classification may be included in preoperative orthognathic planning from the bottom view.
Implementation of the Maryland Global Budget Revenue Model and Variation in the Expenditures and Outcomes of Surgical Care
Authors: Shammas Ronnie L. , Coroneos Christopher J. , Ortiz-Babilonia Carlos , Graton Margaret , Jain Amit , Offodile Anaeze C. 
Published: October 2022

Objective:
To assess the effect of the Global Budget Revenue (GBR) program on outcomes after surgery.

Background:
There is limited data summarizing the effect of the GBR program on surgical outcomes as compared with traditional fee-for-service systems.

Methods:
The Medline, Embase, Scopus, and Web of Science databases were used to conduct a systematic literature search on April 5, 2022. We identified full-length reports of comparative studies involving patients who underwent surgery in Maryland after implementation of the GBR program. A random effects model calculated the overall pooled estimate for each outcome which included complications, rates of readmission and mortality, length of stay, and costs.

Results:
Fourteen studies were included in the qualitative synthesis, with 8 unique studies included in the meta-analysis. Our analytical sample was comprised of 170,011 Maryland patients, 78,171 patients in the pre-GBR group, and 91,840 patients in the post-GBR group. The pooled analysis identified modest reductions in costs [standardized mean difference (SMD) −0.34; 95% CI, −0.42, −0.25; P<0.001], complications [odds ratio (OR): 0.57; 95% CI, 0.36–0.92, P=0.02], readmission (OR: 0.78; 95% CI, 0.72–0.85, P<0.001), mortality (OR: 0.58; 95% CI, 0.47–0.72, P<0.001), and length of stay (standardized mean difference: −0.26; 95% CI, −0.32, −0.2, P<0.001) after surgery.

Conclusions:
Implementation of the GBR program is associated with improved outcomes and reductions in costs among Maryland patients who underwent surgical procedures. This is particularly salient given the increasing need to disseminate and scale population-based payment models that improve patient care while controlling health care costs.
Effects of Umbilical Preparation Before Trans-umbilical Laparo-endoscopic Single-site Surgery on Umbilical Wounds Healing: a Randomized Controlled Trial
Authors: Dai Xuelin , Zhang Yulin , Wang Fulan , Luo Yueying , Gong Yao 
Published: October 2022

Objective:
The umbilicus is the only anatomic entrance and incision site for trans-umbilical laparoendoscopic single-site surgery (TU-LESS). Data on incisional surgical site infections (ISSI) and incision healing in TU-LESS are lacking. Therefore, we aimed to observe umbilical incision healing and possible hernia after TU-LESS and explore the efficacy of preoperative umbilicus preparation on ISSI.

Subjects and Methods:
Consecutive patients aged 18 to 65 years, who were scheduled to undergo TU-LESS at a teaching hospital between March 2020 and November 2021, were enrolled in this prospective study. All patients were randomized to the study group with preoperative umbilicus preparation 30 minutes before patients were sent to the operating room and to the control group without preparation. The umbilical dimple was disinfected twice using povidone-iodine in both groups before the skin incision. The primary outcome was ISSI within 30 days of surgery. Umbilical hernia at 3 months after surgery and perioperative data such as operation time, complications, and incision healing were recorded and compared.

Results:
A total of 400 patients were recruited for this study. TU-LESS was performed in all patients without major complications. ISSI occurred in 5 patients in the study group (2.5%) and 3 patients in the control group (1.5%), with no significant differences between both groups (P=0.479). No umbilical hernia occurred in any patient during the 3 months follow-up. Six patients in the study group (3.1%) and 1 in the control group (0.5%) experienced excessive scarring, a relatively high incidence in the study group, though the difference was not statistically significant (P=0.067).

Conclusions:
TU-LESS-related umbilical hernias are rare with existing suturing methods. Umbilicus preparation before TU-LESS could not decrease ISSI; however, it increased the nursing workload, which should be avoided.
Counterfactual thinking elicits emotional change in young children
Authors: Gautam Shalini , Suddendorf Thomas , Redshaw Jonathan 
Published: October 2022

Adults often reason about what might have happened had they chosen an alternative course of action in the past, which can elicit the counterfactual emotion of regret. It is unclear whether young children's emotions are similarly impacted by counterfactual thinking about past possibilities. In this study, 4- to 9-year-old children (N= 160) opened one of two boxes, which concealed small and large prizes, respectively. Some children had the means to open either box, whereas other children only had the means to open one box. After seeing that the prize they did not obtain was larger than the one they did obtain, children were significantly more likely to report a negative change in emotion when the non-obtained prize had been a straightforward counterfactual possibility than when it had not. This shows that even young children experience counterfactual emotions following choices, which may ultimately drive them to make better choices in the future.This article is part of the theme issue ‘Thinking about possibilities: mechanisms, ontogeny, functions and phylogeny’.
Archaeological evidence for thinking about possibilities in hominin evolution
Authors: Langley Michelle C. , Suddendorf Thomas 
Published: October 2022

The emergence of the ability to think about future possibilities must have played an influential role in human evolution, driving a range of foresightful behaviours, including preparation, communication and technological innovation. Here we review the archeological evidence for such behavioural indicators of foresight. We find the earliest signs of hominins retaining tools and transporting materials for repeated future use emerging from around 1.8 Ma. From about 0.5 Ma onwards, there are indications of technical and social changes reflecting advances in foresight. And in a third period, starting from around 140 000 years ago, hominins appear to have increasingly relied on material culture to shape the future and to exchange their ideas about possibilities. Visible signs of storytelling, even about entirely fictional scenarios, appear over the last 50 000 years. Although the current evidence suggests that there were distinct transitions in the evolution of our capacity to think about the future, we warn that issues of taphonomy and archaeological sampling are likely to skew our picture of human cognitive evolution.This article is part of the theme issue ‘Thinking about possibilities: mechanisms, ontogeny, functions and phylogeny’.
Low back pain care pathways – is the last provider seen more important than the first: A retrospective cohort study
Authors: Elton David , Zhang Meng 
Published: October 2022

AbstractBackgroundThe associations between the type of health care provider (HCP) initially contacted by an individual with low back pain (LBP), guideline concordance, and cost of care are well understood. Less is known about types of HCP that become involved after the initial HCP, particularly the last HCP seen. The purpose of this retrospective cohort study was to examine sequence patterns in the types of HCP involved in an episode of LBP, exposure to 13 types of services, and total cost.MethodsA US national sample of commercially insured individuals with a single episode of non-surgical LBP occurring in 2017-2019 was analyzed using episode of care unit of analysis. The primary independent variable was the type of initial contact HCP. Dependent measures included types of subsequent HCPs involved in an episode of LBP, rate of use of 13 types of health care services, and total cost.Results503,958 individuals aged 18 years and older initially contacted 196,522 different HCPs for an episode of non-surgical LBP. 30.2% of individuals saw a second HCP, 11.8% a third, 5.2% a fourth and 2.5% a fifth. Compared to primary care providers (PCP) (71.0% of episodes), when chiropractors (DC) were the initial contact HCP they were the most likely to be the only and last HCP seen (84.0% of episodes) (risk ratio 1.18, 95% confidence interval 1.18-1.19). DCs were also the most likely to be the last HCP seen when the second HCP in an episode (72.7%) (1.10, 1.09-1.12), the third HCP (67.7%) (1.10, 1.08-1.13), or the fourth HCP (61.6%) (1.13, 1.08-1.17). Physical therapists (PT), while less likely than PCPs to be the only and last HCP seen (60.0%) (0.84, 0.83-0.86), were more likely than PCPs to be the last HCP when the second (70.9%) (1.08, 1.06-1.09), third (63.2%) (1.03, 1.00-1.06), or fourth HCP (60.7%) (1.11, 1.06-1.16) seen during an episode. PTs were the only type of HCP involved in more episodes as the second HCP (7,344) than as the initial HCP (5,114).ConclusionsDCs are the most likely to be the last HCP seen for an episode of non-surgical LBP. PTs are as likely as DCs to be the last HCP seen except when initially contacted by an individual with LBP. There are numerous potential confounders and limitations to consider when interpreting this novel finding.
How do Vampires Suck Blood?
Authors: Gou Meng , Duan Xuyuan , Li Jun , Wang Yaocen , Li Qingwei , Pang Yue , Dong Yonghui 
Published: October 2022

AbstractLampreys are blood-sucking vampires in the marine. From a survival perspective, it is expected that lamprey buccal gland exhibits a repository of pharmacologically active components to modulate the host’s homeostasis, inflammatory and immune responses. Several proteins have been found to function as anticoagulants, ion channel blockers, and immune suppressors in lampreys, while small metabolites have never been explored in detail. In this study, by analyzing the metabolic profiles of 14 different lamprey tissues, we have identified two groups of blood-sucking-associated metabolites, i.e., kynurenine pathway metabolites and prostaglandins, in the buccal gland and they can be injected into the host fish to ensure a steady and sustained blood flow to the feeding site. These findings demonstrate the complex nature of lamprey buccal gland and highlight the diversity in the mechanisms utilized for blood-sucking in lampreys. In addition, a lamprey spatial metabolomics database (https://www.lampreydb.com) was constructed to assist studies using lampreys as model animal. The database contains detailed qualitative, quantitative, and spatial distribution information of each detected metabolite, and users can easily query and check their metabolites of interest, and/or identify unknown peaks using the database.Significance StatementLampreys are one of the two surviving jawless vertebrate groups that hold the key to our understanding of the early vertebrate evolution, adaptive immune origin, and developmental neurobiology. Here, we applied a spatial metabolomics approach to study the lamprey-host interaction. Two groups of metabolites, i.e., kynurenine pathway metabolites and prostaglandins, were found in the lamprey buccal gland, which modulate the host’s homeostasis, inflammatory and immune responses. The establishment of the first tissue-wide spatial lamprey metabolomics database in this study facilitate future studies in biochemistry, clinical chemistry, natural product discovery, medicine, and metabolomics using lampreys as a model animal.
Assessing park qualities of public parks in Cairo, Egypt
Authors: Aly Dalia , Dimitrijevic Branka 
Published: October 2022

PurposeThis article presents an evaluation tool that is designed to assess 12 spatial and managerial qualities of public parks. The tool is applied in evaluating public parks in Cairo to reveal common management practice issues.Design/methodology/approachFeatures and factors of the qualities were defined and evaluated. The tool was then tested by conducting an evaluation of 48 public parks in Cairo and consulting local experts regarding the assessment criteria. These contributed to enhancing the tool, making it more comprehensive and contextualised to Cairo.FindingsApplication of the tool confirms that the tool has the capacity to provide a comprehensive evaluation of a variety of features and can detect key differences between evaluated parks. Analysis highlights that parks in Cairo are not maintained at optimum level and many exhibit serious deterioration that can have negative influences beyond the boundaries of the parks themselves. The majority of these parks also share problems of heavy commercialisation, wasted potentials, fragmentation and separation of uses.Originality/valueThe evaluation tool provides a new and alternative perspective for the evaluation of the built environment. The tool considers the relationships between the different factors of evaluation, rather than reducing the factors to simple checklists. Managers and other practitioners can use the tool to evaluate existing parks or when designing proposals to achieve better standards in the qualities.
Impact of Covid19 on the development of digital service capability for value co-creation: a mediating role of service ecosystem self-adjustment
Authors: Sakaya Ansgar 
Published: October 2022

PurposeThis study aims to examine the impact of Covid19 on service ecosystem self-adjustment (SES_SA) and additionally to explore the mediating role of SES_SA on the relationship between the Covid19 pandemic and the development of digital service capability (DD_SC).Design/methodology/approachData were drawn from 384 business people with the help of a survey questionnaire. The interrelation of the model was examined with the help of structural equation modeling (SEM) using bootstrapping measures in Smart-partial least square (PLS). Three constructs (Covid19, DD_SC and SES_SA) were found with the help of exploratory factor analysis (EFA). Convergent and discriminant validity were obtained through confirmatory factor analysis (CFA) using statistical package for the social sciences-analysis of a moment structures (SPSS-AMOS)-V.23.FindingsThere is a substantial impact of Covid19 on SES_SA and DD_SC. The investigation also discovered that SES_SA significantly impact DD_SC, whereas, Covid19 impact DD_SC indirectly through SES_SA. Age has a significant favorable influence on fear of Covid19.Research limitations/implicationsThere is scant literature linking SES_SA and the DD_SC.Practical implicationsThe study promotes understanding of the contribution of Covid19 and SES_SA in the DD_SC among business people to enhance value co-creation. Capitalizing on DD_SC will enhance customer experience, assist customers in decision-making, and foster digital economic growth.Originality/valueIt enlightens on the digital capabilities needed for creating and co-creating value. Most studies in this area are qualitative/conceptually based and have not studied this kind of interrelation. Hence, it’s the only quantitative study that has examined the inter-relations among Covid19, SES_SA and DD_SC using SEM. This study also offers comprehension of all theories used in this context by relating Covid19 effects to DD_SC.
Inclusive sustainable business practices in supporting dairy supply chains
Authors: Ciubotaru Marcela 
Published: October 2022

PurposeFood supply chains are facing significant changes and challenges coming from the need to adopt inclusive business practices and foster sustainable development. The current research aims to provide insights related to the inclusiveness of sustainable business practices of a dairy production co-operative where the smallholders are engaging with a traditional business mind-set. The purpose of the research is to deliver insights about the linkages between accounting and business practices in the adoption of an inclusive business model.Design/methodology/approachThis research is based on the qualitative case study of a medium-sized production cooperative company operating in the dairy industry supply chain.FindingsThis study answers the call for research on accounting and control systems in the food sector, by exploring how management and control system is practised within contemporary supply chains. The research aims to analyse the contextual insights of managerial and organizational practices that facilitate inter-organizational relationships and coordination among actors that engage along the supply chain.Research limitations/implicationsThe main limitation relates to the conditions of the time available and the limited number of interviews. Even if key actors were interviewed, a larger sample would have been more beneficial to the research. However, the lack of proper results for accounting tools and software access caused some loss to the research.Originality/valueThis paper emphasizes the effects of the “inclusiveness” of the sustainable business models between suppliers and leading companies by enhancing the sustainable business development within the supply chain, as part of a wider business model in the food sector from an inter-organizational perspective.