bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recurrent group G Streptococcus bacteremia: A case report and literature review
Authors: Ghazanfar Haider , Qureshi Zaheer , Kalangi Harika , Ata Subhan , Jyala Abhilasha , Perez Esther Arguello 
Published: August 2022

AbstractStreptococci group G is an important opportunistic pathogen and causes a wide variety of infections, including pharyngitis, skin and soft tissue infections, bacteremia, endocarditis, septic arthritis, intra‐abdominal infections, meningitis, and streptococcal toxic shock‐like syndrome. As a result, we discuss an interesting case of recurrent group G streptococcal bacteremia in a 68‐year‐old man presenting with altered mental status. We also discuss the risk factors, etiology, pathophysiology, diagnosis, and treatment of group G streptococcal bacteremia.
Penetrating buttock trauma: A life‐threatening injury that highlights the importance of good collaboration with trauma receiving hospitals
Authors: Angelou Dimitrios , McKeever Mark , Doran Amy , Malik Momin 
Published: August 2022

AbstractA 54‐year‐old lady was brought to our emergency department after falling from a stepladder onto the base of her artificial Christmas tree. The metallic rod impaled her through the right buttock. X‐rays and a computerized tomography were performed prior to transport to a trauma center causing delays to her surgery.
Hiatal hernia presenting as a left atrial mass
Authors: Kalavakunta Jagadeesh Kumar , Po Jose Ricardo F. 
Published: August 2022

AbstractCardiac masses pose diagnostic challenges. We present a 62‐year‐old woman presented for evaluation of chest pain and palpitations. Transthoracic echocardiography showed left atrial mass, which was subsequently identified as hiatal hernia by cardiac magnetic resonance imaging.
Dual BRCA1 and BRCA2 pathogenic variants in an adolescent with syndromic intellectual disability
Authors: Algouneh Arash , Caudle Michelle , Balci Tugce , Andrade Andrea , Penava Debbie , Saleh Maha 
Published: August 2022

AbstractPathogenic variants in the BRCA1 and BRCA2 genes are associated with increased risk for breast and ovarian cancers. Concurrent mutations in both genes in the same individual are rare but pose specific challenges when identified, usually through multigene panel testing or infrequently from a genome‐wide analysis, such as whole‐exome sequencing (WES). We present a 15‐year‐old female patient with syndromic intellectual disability whose exome reanalysis identified secondary findings of pathogenic BRCA1 and BRCA2 variants, both inherited paternally. We discuss the significant challenges posed by this finding in genetic counseling and cancer risk management of an adolescent with nonverbal intellectual disability, as well as the impact on their family. This rare case highlights the potential increased diagnostic yield of whole exome sequencing reanalysis and the consequences of secondary medically actionable results in a pediatric patient.
Suprachoroidal hemorrhage during phacoemulsification surgery associated with recent COVID‐19: A report of two cases
Authors: Jamali Hossein , Sadeghi Elham , Nowroozzadeh Mohammad Hossein 
Published: August 2022

AbstractTo report two cases of suprachoroidal hemorrhage during otherwise uncomplicated phacoemulsification, in whom COVID‐19 was documented with a positive PCR test about 1 month before the surgery and the importance of postponing elective surgeries for several months after infection.
Immediate improvement in GCS following needle aspiration of bilateral traumatic subdural effusion in a child in emergency room
Authors: Khizar Ahtesham , Kumar Yadav Pradhumna 
Published: August 2022

AbstractA minor head injury can cause traumatic subdural effusion in a child. They often present to pediatric emergencies initially, and there is a delayed referral to neurosurgery. In the emergency room, they should undergo subdural effusion needle aspiration, which can result in an immediate improvement in GCS.
Silence by the LAMS: Primary lumen‐apposing metal stent for a colorectal anastomotic stricture (with video)
Authors: Zimmer Vincent 
Published: August 2022

AbstractLumen‐opposing metal stents (LAMS) are evolving as novel treatment options in postsurgical strictues. Data on lower GI tract applications, however, are still limited, and technical procedural details need to be refined. This singular clinical report adds to the emerging experience in colorectal stricture treatment by LAMS.
Baclofen overdose: A curious case of medical sales representative
Authors: Gautam Swotantra , Neupane Aakash , Chamlagain Mandita , Pokhrel Sandip , Neupane Durga , Acharya Rochana , Panthi Sagar 
Published: August 2022

AbstractIn this case report, a medical sales representative consumed 250 mg of Baclofen out of curiosity. Baclofen has life‐threatening complications like seizures, respiratory depression, and coma. A majority of patients recover on symptomatic treatment. Baclofen has a great potential for abuse and overdose; therefore, its use must be strictly monitored.
Elucidating the Nature of the External Acid Sites of ZSM‐5 Zeolites Using NMR Probe Molecules
Authors: Bornes Carlos , Stosic Dusan , Geraldes Carlos F. G. C. , Mintova Svetlana , Rocha João , Mafra Luís 
Published: August 2022

AbstractThe identification of acid and nonacid species at the external surface of zeolites remains a major challenge, in contrast to the extensively‐studied internal acid sites. Here, it is shown that the synthesis of zeolite ZSM‐5 samples with distinct particle sizes, combined with solid‐state NMR and computational studies of trimethylphosphine oxide (TMPO) adsorption, provides insight into the chemical species on the external surface of the zeolite crystals. 1H–31P HETCOR NMR spectra of TMPO‐loaded zeolites exhibit a broad correlation peak at δP ∼35–55 ppm and δH ∼5–12 ppm assigned to external SiOH species. Pore‐mouth Brønsted acid sites exhibit 31P and 1H NMR resonances and adsorption energies close to those reported for internal acid sites interacting with TMPO. The presence of an external tricoordinate Al‐Lewis site interacting strongly with TMPO is suggested, resulting in 31P resonances that overlap with the peaks usually ascribed to the interaction of TMPO with Brønsted sites.
B(C6F5)3‐Catalyzed E‐Selective Isomerization of Alkenes
Authors: Kustiana Betty A. , Elsherbeni Salma A. , Linford‐Wood Thomas G. , Melen Rebecca L. , Grayson Matthew N. , Morrill Louis C. 
Published: August 2022

AbstractHerein, we report the B(C6F5)3‐catalyzed E‐selective isomerization of alkenes. The transition‐metal‐free method is applicable across a diverse array of readily accessible substrates, giving access to a broad range of synthetically useful products containing versatile stereodefined internal alkenes. The reaction mechanism was investigated by using synthetic and computational methods.
Enantiospecific Syntheses of Congested Atropisomers through Chiral Bis(aryne) Synthetic Equivalents
Authors: Dauvergne Guillaume , Naubron Jean‐Valère , Giorgi Michel , Bugaut Xavier , Rodriguez Jean , Carissan Yannick , Coquerel Yoann 
Published: August 2022

AbstractThe synthetic equivalents of the enantiopure binaphthyl bis(aryne) atropisomers derived from BINOL (1,1′‐bi‐2,2′‐naphtol) featuring a stereogenic axis vicinal to the two reactive triple bonds can be generated for the first time in solution in an enantiospecific manner. Using a two‐step sequence based on the bidirectional [4+2] cycloaddition of furan derivatives followed by an aromatizative deoxygenation reaction, several 9,9’‐bianthracenyl‐based atropisomers could be prepared enantiospecifically in high enantiomeric purity. Alternatively, bidirectional reactions with anthracene, 2‐bromostyrene, and perylene as the arynophiles afforded very congested bis(benzotriptycene), bis(tetraphene) and bis(anthra[1,2,3,4‐ghi]perylene) nanocarbon atropisomers in equally high enantiomeric purity. In complement, cross reactions with two different arynophiles revealed possible. The unusual atropisomer prototypes described in this study open the way to enantiopure nanographene atropisomers designed for functions.
The effect of mandatory IFRS adoption on the value of cash: The case of Canada
Authors: Gong Sabrina (Dan) , Huson Mark R. , Wier Heather A. 
Published: August 2022

AbstractThis paper presents evidence that Canada's 2011 adoption of IFRS improved Canadian firms' access to external financing. We use a matched sample of Canadian and US firms and find that the marginal value of cash decreased significantly in Canadian firms following mandatory IFRS adoption in Canada. The post‐IFRS decrease in the marginal value of cash is most evident for firms that have a larger number of similar firms in non‐Canadian IFRS regimes. This is consistent with IFRS creating a uniform set of accounting standards that lowers the information costs of cross‐border financing. We also find larger IFRS‐related decreases in the value of cash for firms with high growth potential and low availability of internal cash.
The Influence of Deuterium Isotope Effects on Structural Rearrangements, Ensemble Equilibria, and Hydrogen Bonding in Protic Ionic Liquids
Authors: Khudozhitkov Alexander E. , Stange Peter , Paschek Dietmar , Stepanov Alexander G. , Kolokolov Daniil I. , Ludwig Ralf 
Published: August 2022

AbstractWe report strong isotope effects for the protic ionic liquid triethylammonium methanesulfonate [TEA][OMs] by means of deuterium solid‐state NMR spectroscopy covering broad temperature ranges from 65 K to 313 K. Both isotopically labelled PILs differ in non‐deuterated and fully deuterated ethyl groups of the triethyl ammonium cations. The N−D bond of both cations is used as sensitive probe for hydrogen bonding and structural ordering. The 2H NMR line shape analysis provides the deuteron quadrupole coupling constants and the characteristics of a broad heterogeneous phase with simultaneously present static and mobile states indicating plastic crystal behavior. The temperatures where both states are equally populated differ by about 80 K for the two PILs, showing that deuteration of the ethyl groups in the trialkylammonium cations tremendously shifts the equilibrium towards the static state. In addition, it leads to a significant less cooperative transition, associated with a significantly reduced standard molar transition entropy.
Worldwide Interoperability for Microwave Access network optimization with and without relay station for next generation internet access
Authors: Khan Mubeen Ahmed , Kumar Awanit , Bandhu Kailash Chandra 
Published: August 2022

SummaryEnhancement of network performance is a big challenge today for the emerging technology based on IEEE 802.16. Wireless technology is an alternate solution to wired technology. Network availability all the way is an important challenge in day‐to‐day life. Due to the huge population, the availability of the network is again a big challenge. Also, it becomes more difficult to capture the network if considering rural areas, hilly, lakes, and seashores today. This work proposed relay stations in WiMAX (Worldwide Interoperability for Microwave Access) networks along with various bandwidth allocation algorithms to increase the signal strength over the long distance using retransmission of the original signal by relay station and extend the coverage with a higher data rate and higher user capacity. The availability of WiMAX networks for the channel bandwidth assignment to users for data and service is very important in today's scenario. This paper focuses on evaluating the performance of bandwidth allocation algorithms in light WiMAX networks with and without relay stations. The performance evaluation is done by increasing the number of nodes with various bandwidth allocation techniques with and without relay stations. In this work the round robin and strict priority algorithms are used for channel bandwidth allocation in a light WiMAX network and performance is analyzed through throughput, goodput, and packet drop rate, which will help to implement and configure the suggested optimal parameters in the production environment. This work enhanced the throughput and goodput and reduce the dropout rate, and the user capacity also increased.
Multi‐image flock size estimation with CountEm: A case study with half a million Common Eiders and Greater Snow Geese
Authors: Cruz Marcos , González‐Villa Javier , Lefebvre Josée , Gilliland Scott G. , St‐Pierre Francis , English Matthew , Lepage Christine 
Published: August 2022

AbstractMany of the methods used for estimating population size from ecological surveys have limitations on precision, cost, and/or applicability. The CountEm method was proposed recently for estimating the number of individuals in large groups from single images. It is simple and efficient, and can be applied to any species. Here we present a case study by applying CountEm to a real ecological survey with 278 images of Greater Snow Geese (Anser caerulescens atlanticus) and Common Eiders (Somateria mollissima) flocks taken from fixed‐wing aircraft in Eastern Canada. First, we evaluated the precision and counting time of CountEm on single images. Second, we developed and tested a new multi‐image version of the CountEm software. We show that flock sizes of N > 35,000 can be estimated on single images in ∼5 min, from counting a sample of ∼200 birds, yielding relative SEs in the 5%−10% range. Processing times increased to 10–20 min when simultaneously processing large numbers of images that contained over half a million birds with only modest increases in relative SE (range: 10%−15%). Our results suggest that CountEm may be used to save time and resources if incorporated into monitoring programs that utilize imagery in the abundance estimates.
Optimal scheduling of DG and EV parking lots simultaneously with demand response based on self‐adjusted PSO and K‐means clustering
Authors: Abo‐Elyousr Farag K. , Sharaf Adel M. , Darwish Mohamed M. F. , Lehtonen Matti , Mahmoud Karar 
Published: August 2022

AbstractRecently, the proliferation of distributed generation (DG) has been intensively increased in distribution systems worldwide. In distributed systems, DGs and utility‐owned electric vehicle (EV) to grid aggregators have to be efficiently scaled for cost‐effective network operation. Accordingly, with the penetration of power systems, demand response (DR) is considered an advanced step towards a smart grid. To cope with these advancements, this study aims to develop an innovative solution for the day‐ahead sizing approach of energy storage systems of EVs parking lots and DGs in smart distribution systems complying with DR and minimizing the pertinent costs. The unique feature of the proposed approach is to allow interactive customers to participate effectively in power systems. To accurately solve this optimization model, two probabilistic self‐adjusted modified particle swarm optimization (SAPSO) algorithms are developed and compared for minimizing the total operational costs addressing all constraints of the distribution system, DG units, and energy storage systems of EV parking lots. The K‐means clustering and the Naive Bayes approach are utilized to determine the EVs that are ready to participate efficiently in the DR program. The obtained results on the IEEE‐24 reliability test system are compared to the genetic algorithm and the conventional PSO to verify the effectiveness of the developed algorithms. The results show that the first SAPSO algorithm outperforms the algorithms in terms of minimizing the total running costs. The finding demonstrates that the proposed near‐optimal day‐ahead scheduling approach of DG units and EV energy storage systems in a simultaneous manner can effectively minimize the total operational costs subjected to generation constraints complying with DR.
Developmental Polyethylene Microplastic Fiber Exposure Entails Subtle Reproductive Impacts in Juvenile Japanese Medaka (Oryzias latipes)
Authors: DiBona Elizabeth , Haley Carol , Geist Simon , Seemann Frauke 
Published: August 2022

Abstract
Microplastic pollution has been recognized as a potential threat to environmental and human health. Recent studies have shown that microplastics reside in all ecosystems and contaminate human food/water sources. Microplastic exposure has been shown to result in adverse effects related to endocrine disruption; however, data are limited regarding how exposure to current environmental levels of microplastics during development may impact reproductive health. To determine the impact of environmentally relevant, chronic, low-dose microplastic fibers on fish reproductive health, juvenile Japanese medaka were exposed to five concentrations of polyethylene fibers for 21 days, and reproductive maturity was examined to assess the later life consequences. Fecundity, fertility, and hatching rate were evaluated to determine the organismal level impacts. Gonadal tissue integrity and stage were assessed to provide insights into potential tissue level changes. Expression of key reproductive genes in male and female gonads provided a molecular level assessment. A significant delay in hatching was observed, indicating cross-generational and organismal level impacts. A significant decrease in 11-beta-dehydrogenase isozyme 2 (HSD11β2) gene expression in male medaka indicated adverse effects at the molecular level. A decrease in male expression of HSD11β2 could have an impact on sperm quality because this enzyme is crucial for conversion of testosterone into the androgen 11-ketotestosterone. Our study is one of the first to demonstrate subtle impacts of virgin microplastic exposure during development on later life reproductive health. The results suggest a possible risk of polyethylene fiber exposure for wild fish during reproductive development, and populations should be monitored closely, specifically in spawning and nursery regions. Environ Toxicol Chem 2022;41:2848–2858. © 2022 SETAC
Enhanced hair growth effects through low‐level vortex beams radiation: An experimental animal study
Authors: Zhou Ning , Huang Ziling , Xu Zhenyu , Yin Yue , He Yancong , Huang Lingxiao , Dai Linmao , Li Xiaochun , Fu Siqi , Huang Huihui 
Published: August 2022

AbstractPhotobiomodulation therapy (PBMT) is a non‐invasive and pain‐less treatment for hair loss. Researches on PBMT rarely considered the impact of different light structures. In this study, we irradiated shaven rats with both 650 nm, m = 32 vortex beams and ordinary Gaussian beams. The laser treatment was performed at 24‐hour intervals for 20 days. The energy density was set to 4.25 J/cm2. The results indicated that low‐level vortex beam irradiation led to better stimulation of hair growth than the Gaussian beams, which might be related to deeper penetration. The underlying biological mechanisms are discussed in terms of the activation of Wnt/β‐catenin/sonic hedgehog pathway. Our results suggest that low‐level vortex beam irradiation is advantageous to the treatment of hair loss because it is technically feasible, convenient and effective.
The potency of common proinflammatory cytokines measurement for revealing the risk and severity of anxiety and depression in psoriasis patients
Authors: Tong Nannan , Zhang Yu , Yang Anping , Dai Xiaoli , Hao Siyu 
Published: August 2022

AbstractObjectiveProinflammatory cytokines mediate anxiety and depression in various ways, such as immunity, inflammation, and the hypothalamic–pituitary–adrenal axis. This study intended to further explore the linkage of common proinflammatory cytokine levels with anxiety and depression in psoriasis patients.MethodsTotally, 150 psoriasis patients and 50 healthy controls (HCs) were included; the serum samples were collected, then common proinflammatory cytokines were measured by ELISA. Hospital Anxiety and Depression Scale (HADS) was assessed.ResultsHADS‐anxiety (HADS‐A) score, HADS‐depression (HADS‐D) score, TNF‐α, IL‐1β, IL‐6, IL‐12, IL‐17A, and IL‐23 were all increased in psoriasis patients compared to HCs (allp < 0.05). In psoriasis patients, TNF‐α (p = 0.001), IL‐12 (p = 0.035), and IL‐17A (p < 0.001), but not IL‐1β (p = 0.255), IL‐6 (p = 0.248), and IL‐23 (p = 0.216), were positively linked to HADS‐A score. Meanwhile, TNF‐α (p = 0.007) and IL‐17A (p = 0.007) were enhanced in psoriasis patients with anxiety in contrast to those without anxiety; whereas IL‐1β (p = 0.178), IL‐6 (p = 0.360), IL‐12 (p = 0.239), and IL‐23 (p = 0.450) were not different. TNF‐α (p < 0.001), IL‐1β (p = 0.013), Il‐17A (p < 0.001), and IL‐23 (p = 0.023), but not IL‐6 (p = 0.143) and IL‐12 (p = 0.158), were positively linked to HADS‐D score. Concurrently, TNF‐α (p = 0.015), IL‐17A (p < 0.001), and IL‐23 (p = 0.017) were climbed in psoriasis patients with depression by comparison to those without depression; whereas IL‐1β (p = 0.113), IL‐6 (p = 0.237), IL‐12 (p = 0.660) did not differ.ConclusionTNF‐α, IL‐17A, and IL‐23 increments reflect anabatic anxiety and depression in psoriasis patients, uncovering the potency of proinflammatory cytokines measurement for monitoring or even preventing psoriasis patients' anxiety and depression.
Study of the Association of Single Nucleotide Polymorphisms in Candidate Genes With Sevoflurane
Authors: Zhao Shuai , Huang Shiqian , Zhong Qi , Han Linlin , Wang Yafeng , Xu Feng , Ma Lulin , Ding Yuanyuan , Xia Leiming , Chen Xiangdong 
Published: August 2022

AbstractThe susceptibility of different individuals to anesthetics varies widely, and sevoflurane is no exception. We hypothesized that polymorphisms in genes involved in pharmacokinetics and pharmacodynamics may explain this variation. A total of 151 individuals undergoing otorhinolaryngology surgery were included. The influence of genetic polymorphisms on sevoflurane sensitivity were investigated through SNaPshot technology. Individuals carrying KCNK2 rs6686529 G > C, MTRR rs3733784 TT, rs2307116 GG, or rs1801394 AA polymorphisms had a higher sensitivity to the sedative effect of sevoflurane than those without those polymorphisms. The univariate linear regression analysis indicated that MTRR rs3733784 TT, rs2307116 GG, and rs1801394 AA were potentially significant predictors of higher sensitivity to the sedative effect of sevoflurane. Moreover, CYP2E1 rs3813867 G > C and rs2031920 C > T, GABRG1 rs279858 T > C, KCNK3 rs1275988 CC, GRIN2B rs1806201 GG, MTRR rs2307116 G > A, and rs1801394 A > G were associated with a higher sensitivity to the cardiovascular effect of sevoflurane. Our results suggested that 9 single nucleotide polymorphisms in genes involved in metabolizing enzymes, transport proteins, target proteins of sevoflurane and folate metabolism may help to explain individual differences in the susceptibility to the sedative or cardiovascular effect of sevoflurane.
Using time‐weighted average change from baseline of SARS‐CoV‐2 viral load to assess impact of hydroxychloroquine as postexposure prophylaxis and early treatment for COVID‐19
Authors: Kumbhakar Raaka , Neradilek Moni , Barnabas Ruanne V. , Stewart Jenell , Stankiewicz Karita Helen C. , Landovitz Raphael J. , Kissinger Patricia J. , Jerome Keith R. , Paasche‐Orlow Michael K. , Bershteyn Anna , Chu Helen Y. , Neuzil Kathleen M. , Greninger Alexander L. , Luk Alfred , Wald Anna , Brown Elizabeth R. , Johnston Christine 
Published: August 2022

AbstractTwo randomized controlled trials demonstrated no clinical benefit of hydroxychloroquine (HCQ) for either postexposure prophylaxis or early treatment of SARS‐CoV‐2 infection. Using data from these studies, we calculated the time‐weighted average change from baseline SARS‐CoV‐2 viral load and demonstrated that HCQ did not affect viral clearance.