bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional psychopaths? Differentiation of various emotional states experienced by psychopathic individuals
Authors: Bolek Ewelina , Trzebińska Ewa , Braniecka Anna 
Published: November 2022

Abstract
The study examined experience of different forms of emotion by people exhibiting strong psychopathic traits and to compare them in this regard with non-psychopathic individuals. One hundred and twenty-six individuals took part in a computer experiment in which they were shown six excerpts from the film evoking various forms of emotions: (1) negative emotion, (2) positive emotion, (3) simultaneously mixed emotion, (4) sequentially mixed emotion (positive following negative), (5) secondary emotion mixed, (6) lack of emotion. Subsequently they reported (1) the intensity of the emotions experienced, (2) the tension and (3) ambivalence associated with them. The severity of psychopathic traits was measured using the Self-Report Psychopathy Scale-III. Results revealed that people with stronger psychopathic traits experienced these particular forms of emotions in a different way to others. The differences are related to negative emotions and sequentially mixed emotions. Negative emotions were experienced by psychopathic people at greater intensity and, accompanied by greater tension. In addition, two aspects of psychopathy: criminal tendencies in its less severe form and interpersonal manipulation were shown to be moderators for these differences, confirming previous findings that psychological traits are the primary mechanisms of psychopathy, rather than antisocial behavior itself.
Rapid Determination of 61 Acid Industrial Dyes in Chili Patse, Hotpot Seasoning, Bearnaise Using Double-Liquid Liquid Extraction and Ultrahigh-performance Liquid Chromatography Quadrupole Orbitrap High-resolution Mass Spectrometry
Authors: Li Shuang , Meng Yanan , Zhang Shun , Cai Ting 
Published: November 2022

Abstract
A rapid screening method of 61 acid dyes in complex food matrix such as chili patse, hotpot seasoning, bearnaise was proposed by using double liquid-liquid extraction (d-LLE), which can maximum remove interference from lipid-soluble compounds and highly hydrophilic compounds. The extract was analyzed by ultrahigh-performance liquid chromatography quadrupole orbitrap high-resolution mass spectrometry (UPLC-Q-Orbitrap-HRMS). The preliminary qualitative analysis was performed by extracting characteristic ion fragments (m/z 79.9557) based on in-source collision induced dissociation (CID) in full scan MS. Linearity was observed in the range of 0.01 ~ 0.2 µg/mL and the limits of quantification were 0.05 mg/kg for 61 acid dyes. The average recoveries were 75.2% ~ 95.3%, with RSD ≤ 10%. The proposed method has the ability to rapid screen acid dyes in complex foods with high economy, sensitivity and reliability.
Electrical approach for decontaminating a multi-metal polluted soil as influenced by electrolyte type and soil position
Authors: Keshavarz Samira , Ghasemi-Fasaei Reza , Ronaghi Abdolmajid , Mousavi Ali Akbar 
Published: November 2022

Abstract
The remediation of heavy metals contaminated soils is increasingly a global problem with serious implications for human health. This study aimed to evaluate the in-situ remediation performance of multi element contaminated soil by the electrokinetic. To achieve this, the effects of chelating agents (water, ethylenediamine tetraacetic acid (EDTA), diethylenetriamine pentaacetic acid (DTPA)), potential gradient (0, 1, and 2 V cm− 1), and position of soil in electrokinetic cell on metals fractions and metals removal were investigated. The results revealed that the electric potential difference and application of EDTA or DTPA electrolyte generally enhanced heavy metals removal efficiency and for Ni and Pb the interactions effects of these factors were significantly positive. Results showed that Ni, Zn, Cd, and Pb removal efficiency is highest with DTPA, DTPA, EDTA and EDTA electrolytes, respectively. In particular, the usage of electric current remarkably shifted the soil-metal bonds from stable (residual) to a less stable (mobile and mobilisable) fraction. The optimum electric current for the removal of Zn, Cd, and Ni was 1, 1, and 2 V cm− 1, respectively, which removed 44, 47 and 41% of the average of these heavy metals in soil, respectively. Results of present study demonstrated that removal efficiency was highly metal-dependent; and the order of metals removal was Cd > Ni > Zn > Pb.
Using multi-criteria decision analysis to describe stakeholder preferences for new quality improvement initiatives that could optimise prescribing in England: A case study
Authors: Khanal Saval , Schmidtke Kelly Ann , Talat Usman , Turner Alice M , Vlaev Ivo 
Published: November 2022

Abstract
Background

Hospital decision-makers have limited resources to implement quality improvement projects. To decide which interventions to take forward, trade-offs must be considered that inevitably turn on stakeholder preferences. The multi-criteria decision analysis (MCDA) approach could make this decision process more transparent.

Method

An MCDA was conducted to rank-order four types of interventions that could optimise medication use in England’s National Healthcare System (NHS) hospitals, including Computerised Interface, Built Environment, Written Communication, and Face-to-Face Interactions. Initially, a core group of quality improvers (N = 10) was convened to determine criteria that could influence which interventions are taken forward according to the Consolidated Framework for Implementation Research. Next, to determine preference weightings, a preference survey was conducted with a diverse group of quality improvers (N = 356) according to the Potentially All Pairwise Ranking of All Possible Alternatives method. Then, rank orders of four intervention types were calculated according to models with criteria unweighted and weighted according to participant preferences.

Results

The most important criteria influencing what interventions were preferred was whether they addressed ‘patient needs’ and their financial ‘cost’. In both the unweighted and weighted models, the top-ranked intervention type was Computerised Interface followed by Built Environment. In the unweighted model, Written Communication and Face-to-Face intervention types were ranked similarly, while in the weighted model the Face-to-Face type was ranked lower.

Conclusions

An MCDA was conducted to rank order intervention types that stand to increase medication optimisation across hospitals in England. The top-ranked intervention type was Computerised Interface. This finding does not imply Computerised Interface interventions are the most effective interventions but suggest that successfully implementing lower-ranked interventions may require more conversations to appreciate stakeholder concerns.
Multiscale reconstruction of bronchus and cancer cells in human stage II lung adenocarcinoma
Authors: Li Xin , Zhang Bowen , Liang Yanmei , Li Ting 
Published: November 2022

Abstract
Background
While previous studies primarily focused on the structure of the normal whole mouse lung, the whole bronchus and cytoarchitectural details of the mouse intact lung lobe have been discovered at single-cell resolution. Revealing the sophisticated lung adenocarcinoma structure at three-dimensional (3D) and single-cell level remains a fundamental and critical challenge for the pathological mechanism research of lung adenocarcinoma (LA).
Methods
Fluorescence micro-optical Sectioning Tomography (fMOST) combined with PI staining were used to obtain the 3D imaging of the human LA tissues at single-cell resolution.
Results
With a spatial resolution of 0.32 × 0.32 × 1.0 µm3, the dataset of human LA with single-cell precision consists of two channels, each of which contains information about the bronchi and the cytoarchitecture. The bronchial wall is thicker and the lumen is smaller in the adenocarcinoma tissue, in which its original normal structure is vanished. More solid components, more clustered cancer cells with larger nucleoli, and more significant atypia are found in cancer tissues. In paracancerous tissues, the bronchial wall cells have a monolayer or bilayer structure, cluster along the wall, and are relatively dispersed. Few fibrous structures and occasional dissemination of spread through air spaces (STAS) are observed.
Conclusions
Based on the human lung adenocarcinoma tissue database obtained by fMOST and PI staining, the bronchi and cells were reconstructed and visualized. This work provides a technical roadmap for studying the bronchus and cytoarchitectural structure and their spatial relationship in lung adenocarcinoma tissue, which will help with the accurate diagnosis and assessment of the medical effectiveness of lung adenocarcinoma in the future.
Understanding daily rhythms in weakly electric fish: the role of melatonin on the electric behavior of Brachyhypopomus gauderio
Authors: Vazquez Juan I. , Gascue Valentina , Quintana Laura , Migliaro Adriana 
Published: November 2022

Abstract
Living organisms display an array of molecular, physiological and behavioral rhythms synchronized with natural environmental cycles. Understanding these interactions gains power when the complexity of natural habitats and the diversity of behavioral and physiological adaptations are taken into account. Brachyhypopomus gauderio, a South American weakly electric fish, are characterized by the emission of electrical discharges (EOD), with a very stable rate that is modulated by social and environmental cues. The nocturnal arousal in B. gauderio coincides with a melatonin-dependent EOD rate increase. Here we first show a daily cycle in both the EOD-BR and EOD-BR variability of B. gauderio in nature. We approached the understanding of the role of melatonin on this natural behavior through both behavioral pharmacology and in vitro assays. We report, for the first time in gymnotiformes, a direct effect of melatonin on the PN in vitro preparation. Melatonin treatment lowered EOD-BR in freely moving fish and PN-BR, while increasing the variability of both. These results show that melatonin plays a key role in modulating the electric behavior of B. gauderio through its effect on rate and variability, both of which must be under a tight temporal regulation to prepare the animal for a challenging nocturnal environment.
Hyperproduction of extracellular polymeric substance in Pseudomonas fluorescens for efficient Chromium (VI) absorption
Authors: Yang Lijie , Chen Zhen , Zhang Ying , Lu Fuping , Liu Yihan , Cao Mingfeng , He Ning 
Published: November 2022

Abstract
A novel extracellular polymeric substance (EPS) with flocculating activity produced by Pseudomonas fluorescein isolated from soil was studied in this paper. Firstly, atmospheric and room temperature plasma (ARTP) was applied to get a mutant of P. fluorescein with higher EPS production. A mutant T4-2 exhibited a 106.48% increase in flocculating activity compared to the original strain. The maximum EPS yield from T4-2 was enhanced up to 6.42 g/L, nearly 10 times higher than the original strain on a 3.6-L fermentor with optimized fermentation conditions. Moreover, the flocculating activity of the mutant reached 3023.4 U/mL, 10.96-fold higher than that of T4. Further identification showed that EPS from T4-2 was mainly composed of polysaccharide (76.67%) and protein (15.8%) with a molecular weight of 1.17×105 Da. The EPS showed excellent adsorption capacities of 80.13 mg/g for chromium (Ⅵ), which was much higher than many reported adsorbents such as chitosan and cellulose. The adsorption results were described by Langmuir isotherm and pseudo-second order kinetic model. The thermodynamic parameters (ΔG0, ΔH0 and ΔS0) revealed that the adsorption process was spontaneous and exothermic. Adsorption mechanisms were speculated to be electrostatic interaction, reduction, and chelation.
Acculturation stress and post-traumatic growth among female North Korean defectors: A moderated mediation effect of loneliness and neighborhood social cohesion
Authors: Kim Hokon , Kim Ocksim , Kim Kyung-A , Chu Sang Hui , Chung Misook L. 
Published: November 2022

Abstract
Purpose
Extant literature shows that loneliness negatively predicts post-traumatic growth (PTG) among North Korean defectors (NKD). Female NKD are more vulnerable to various traumatic experience in the entire process from escaping North Korea and to entering South Korea. Evidence also suggests that the experience of migration and settlement to South Korea causes acculturation stress and loneliness and could be affected by neighborhood social cohesion. This study explores the mediating effect of loneliness on relationship between acculturation stress and PTG, and the moderating effect of neighborhood social cohesion on the relationship between acculturation stress and loneliness among female NKD.
Methods
Instruments used were the short-form of the UCLA Loneliness Scale, Post-Traumatic Growth inventory, part of the Neighborhood-level Cohesion and Disorder scale, and the revised Acculturation Stress Scale for International Students for NKD. Data were analyzed from 166 females NKD who participated in an online survey from July to August 2020. Statistical analysis, including mediating and moderating effect analysis, was performed using SPSS 26.0 and PROCESS 4.0.
Results
Loneliness negatively impacted PTG (B=-2.118, p < 0.001), and loneliness mediated the relationship between acculturation stress and post-traumatic growth (B=-0.294, 95% LLCI=-.415, 95% ULCI=-0.186). High neighborhood social cohesion decreased loneliness, and neighborhood social cohesion moderated the relationship between acculturation stress and loneliness (B=-0.018, 95% LLCI=,0.001 95% ULCI = 0.152).
Conclusion
Increasing neighborhood social cohesion in female NKD would reduce loneliness caused by acculturation stress and help their positive growth. This represents the most appropriate approach to help female NKD achieve growth, even after suffering trauma.
Syntheses, Crystal Structure and Fluorescence Properties of a Cd (Ⅱ) coordination polymer based on pyridinium zwitterionic ligand
Authors: Wang Kaimin , Dong Yanqiu , Zhao Xiong , Bai Xuling , Duan Keyan , Ye Yanqing , Guo Jinrong , Wang Zhengliang , Tang Huaijun , Ma Yulu 
Published: November 2022

Abstract
With pyridinium zwitterionic ligand H2LCl2 (1,1'-((2,3,5,6-tetramethyl-1,4-phenylene)bis(methylene))bis(4-carboxypyridin-1-ium)chloride) as the main connection point, a novel Cd (Ⅱ) coordination polymer namely [Cd(L)2(SO4)2(H2O)2][Cd(H2O)6]·4H2O (CP 1) and a partially deprotonated HLClO4·H2O were obtained by room temperature volatilization method. X-ray diffraction studies reveal that HLClO4·H2O crystallizes in the monoclinic P21/n space group, with a bowl shape partially deprotonated HL+ cation as the main structure, and the ClO4-anion which balances the charge just exists outside. When the ligand reacts with CdSO4‧8/3H2O, CP 1 crystallized in the triclinic P-1 space group with two distinct Cd (Ⅱ) centers was obtained. Abundant hydrogen bonds produce the 3D supramolecular structure of CP 1. Elemental analysis, powder X-ray diffraction, infrared spectrum, thermogravimetric analysis, solid-state fluorescence properties and CIE analysis of CP 1 were studied. Results indicate that the CP 1 has good thermal stability and has potential applications in blue luminescent materials.
EIF2S3 is a Prognostic Biomarker Correlated With Immune Infiltration in Hepatocellular Carcinoma
Authors: chen zhonghuo , Wang Wen-Jun , Tang Lei , Wei Chao , Wang Ben , Xiao Han , Tao Xiao-fei , Yang Jia-Le , Yu Tao-Zhi , Guan Jia-Fu , Yuan Rong-Fa , Yu Xin , Hu Zhi-Gang , Wu Hua-Jun , Wang Kai 
Published: November 2022

Abstract
Background: Hepatocellular carcinoma (HCC) is one of the most frequent cancers with a high recurrence rate and poor prognosis. eukaryotic translation initiation factor 2 subunit gamma (EIF2S3) is a heterotrimeric GTP binding protein, taking part in the recruitment of methionyl-tRNA to the 40 S ribosomal subunit. However, the role of EIF2S3 in HCC remains unclear.
Materials and methods: In the present study, the expression level of EIF2S3 in pan-cancer was identified using TIMER database and its level in HCC tissues was detected by TCGA database. Univariate and multivariate Cox regression analysis was performed to evaluate the relationship between EIF2S3 and clinical characteristics in HCC. Kaplan-Meier Plotter analysis was used to assess the prognostic role of EIF2S3 in HCC patients. Function enrichment analysis was conducted by LinkedOmics database. The association between EIF2S3 level and immune infiltration, and the correlation between EIF2S3 expression and immune cell biomarkers in HCC were analyzed by TIMER and GEPIA database. Finally, the protein expression of EIF2S3 in HCC cell lines was analyzed and the proliferation, migration, invasion and apoptosis of HCC cells after silencing EIF2S3, which were detected by cell viability assay, wound healing assay, transwell assay and flow cytometry analysis, respectively.
Results: EIF2S3 was overexpressed in many solid tumors. And, high EIF2S3 expression was detected in HCC and significantly related to tumor status and prognosis of HCC patients. Moreover, EIF2S3 expression was positively related to immune cell infiltration and gene marker of immune cells in HCC patients. Cell experiments showed thatEIF2S3 was overexpressed in HCC cells and EIF2S3 enhanced the proliferation, migration and invasion of HCC cells and decreased the apoptosis of HCC cells.
Conclusion: EIF2S3 may be involved in the development of HCC and could be a prognostic genomic marker and a novel therapeutic target for HCC.
Efficacy of Intrathecal Methotrexate in Children With High-risk Medulloblastoma over 3 years: A retrospective study from a single center
Authors: Zhang YuTong , Wang Yu , Zhang Chao , Zhong Xiaodan , Chang Jian 
Published: November 2022

Abstract
Purpose To evaluate the therapeutic benefits and side effects (especially leukoencephalopathy) of intrathecal methotrexate (MTX) in children aged over three years old with high-risk medulloblastoma (MB).
Patients and Methods In the present retrospective study, patients who received intrathecal MTX during chemotherapy were classified as MTX group, while those receiving cerebrospinal fluid (CSF) cytology analysis only were recruited in control group.
Results Among the 46 MB patients, 32 were classified in MTX group, whereas 14 in control group. For those 32 patients in MTX group, 27 (84.38%) had metastatic disease, 3 (9.38%) had diffuse anaplasia, and 3 (9.38%) had residual disease greater than 1.5 cm2. Molecular subgroup classification was available in 28 (87.5%) patients. Of those 14 patients in control group, 8 (57.14%) had metastatic disease, 3 (27.27%) had diffuse anaplasia, and 6 (42.86%) had residual disease greater than 1.5 cm2. Molecular subgroup classification was available in 6 (42.86%) patients. The 5-year progression-free survival (PFS) was 70.99% (95% CI, 58.22%-90.42%) and 5-year overall survival (OS) was 72.99% (95% CI, 60.41%-93.06%) for MTX group, while those were 41.67% (95% CI, 17.93%-66.92%) and 50% (95% CI, 27.88%-77.14%) for control group, separately. Among the 32 patients in MTX group, 6 (18.75%) with group 4 disease developed MTX-related acute leukoencephalopathy and one of them died.
Conclusions Intrathecal MTX improves the 5-year PFS and OS for children with high-risk MB. However, intrathecal MTX is not recommended for patients with group 4 MB due to the high risk of acute leukoencephalopathy.
Galvanic displacement of Co with Rh boosts hydrogen and oxygen evolution reactions in alkaline media
Authors: Vasiljević Bojana Nedić , Jovanović Aleksandar Z. , Mentus Slavko V. , Skorodumova Natalia V. , Pasti Igor 
Published: November 2022

Abstract
The growing energy crisis put an emphasis on the development of novel efficient energy conversion and storage systems. Here we show that surface modification of cobalt by a fast galvanic displacement with rhodium significantly affects the activity towards hydrogen (HER) and oxygen evolution (OER) in alkaline media. After only 20 seconds of galvanic displacement, the HER overpotential is reduced by 0.16 V and OER overpotential by 0.06 V. This reduces the predicted water splitting voltage from 2.03 V (clean Co anode and cathode) to 1.81 V at 10 mA cm− 2. During the galvanic displacement process, the surface roughness of the Co electrode does not suffer significant changes, which suggests an increase in the intrinsic catalytic activity. Density Functional Theory calculations suggest that the reactivity of the Rh-modified Co(0001) surface is modified compared to the clean one. In the case of HER, experimentally observed activity improvements are directly correlated to the weakening of the hydrogen-surface bond, confirming the beneficial role of Rh incorporation into the Co surface.
SMARCA4-deficient dedifferentiated endometrioid carcinoma
Authors: Huang Ruihong , Chen Lvxuan , Pan Canyu , Zhang Peiru , Fang Xueting , Yi Jingyi 
Published: November 2022

Abstract
Background
SMARCA4-deficient, dedifferentiated endometrioid carcinoma （SDDEC）with distinct rhabdoid cells is a rare uterine malignancy. A 58-year-old case was presented.The undifferentiated carcinoma component was 90% and filled with rhabdoid cells, which is easily mistaken for SMARCA4-deficient undifferentiated uterine sarcoma (SDUS). In contrast to earlier findings, the undifferentiated carcinoma component's MMR status was distinct from that of endometrioid adenocarcinoma. We discuss the clinicopathological characteristics, the clinical course of treatment, and a literature review.
Case presentation
The patient was 58 years old and admitted with postmenopausal vaginal bleeding and lower abdominal pain. An MRI revealed a significant uterine tumor and an ambiguous sigmoid colon boundary. A cytoreductive procedure was carried out. A CT scan performed two weeks after surgery revealed liver metastases and new, enlarged lymph nodes in the mediastinum. Anti-PD-1 immunotherapy was tested. One month after the procedure, the patient died. The final pathological diagnosis was SMARCA4-deficient dedifferentiated endometrial carcinoma. SMARCA4 loss was only present in the undifferentiated carcinoma, which manifested as MMRp. As well, the endometrioid adenocarcinoma component had intact SMARCB1 and SMARCA4 expression, which manifested as MMRd.
Conclusion
Mutations in SMARCA4 result in clinically hyperaggressive malignant rhabdomyoblastic tumors.Future research will focus heavily on multimodal therapy, which combines surgical tumor removal, postoperative chemotherapy, radiation, and immunotherapy, for SDDEC.