bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Prescribing Patterns of Antihypertensive Drugs and Risk Factors Associated with Hypertension in Tertiary Care Hospital
Authors: Tom Cyril , John Ajo , SA Babu Arya , Sahil Mohammed , Narayanan Navya 
Published: April 2022

Aim/Background: To assess the prescribing pattern of anti-hypertensive and to assess the risk factors associated with hypertension.
Materials and methods: The prospective observational study was carried out for 6 months among 31 in-patients in the various departments of Yenepoya Medical College Hospital, Mangalore. Patients of both sex aged 18 years and above, those who can understand oral and written information and those diagnosed with hypertension were added in the study. Out-patients, patients with mental or psychiatric diseases, cognitive dysfunction, patients on cancer chemotherapy, pregnant and lactating females were excluded. A suitably designed data collection form was prepared to collect the data.
Results: Out of 31 patients, hypertension was mainly affected in males above the age of 60years. In the study, majority (41.9%) of the participants had Stage II Hypertension according to JNC 7 classification. The major risk factors associated with Hypertension was advanced age (41.9%) followed by alcoholism (12.9%) on basis of environmental risk factor and diabetes (64.5%) on disease basis. Study reveals that Type II DM was comorbidity in most of the patient’s i.e., 19(61.3%), followed by 15(48.4%) patients with CKD. 25.8% patients recieved monotherapy while majority of the patients i.e., 74.2% received triple therapy. The most commonly prescribed drug was Furosemide (Diuretics) 18(58.1%), followed by Clonidine (Alpha agonist) 13(41.9%). The result also shows that, after health education for patients with hypertension, BP is substantially lowered.
Conclusion: Study reveals that advancing age was the most predominating risk factor among hypertensive patients. Diuretics (Furosemide), Alpha agonist (Clonidine) and Calcium channel blocker (Amlodipine) were the drug of choice for hypertensive patients in the hospital. Drug therapy along with patient counseling helped to lower BP to an extent.
Keywords: Antihypertensive drug, prescribing pattern, risk factors, hypertension, co-morbidities with hypertension
Antibiotic prescription practice at veterinary pharmaceutical shops and its potential impact on the development of antimicrobial resistance in Moshi, Northern Tanzania
Authors: MKALA REUBEN SUNZU 
Published: April 2022

Aim: We aimed to investigate antibiotic prescription practice in veterinary shops and its potential impact on the development of antimicrobial resistance.
Methods: A correlation cross-sectional study was carried out in Moshi, Tanzania. A convenient sampling method was used to enroll 80 study participants and 80 Veterinary pharmaceutical shops selling antibiotics for cattle. The study questionnaire was administered to both pharmaceutical sellers and cattle keepers Results: A total of 80 veterinary pharmaceutical shops visited to deliver information about antibiotics sold with or without prescription from veterinary professionals and eighty (80) human participants. Most of the study participant 66/80 (82.5%) responded to started treatment before laboratory diagnosis and diagnosis was mainly based on symptoms and signs 58/80 (72.5%); owners description 17/80 (21.3%) and less frequently on none specific reason 15/80 (6.5%) (Χ2=77.89, P= 0.000, OR=0.875, 95% CI= 0.803-0.947). Tetracycline 30 (100%), Trimethoprim/sulfamethoxazole 10 (100%), and amoxicillin/clavulanic acid 7 (100%) were highly sold unprescribed drugs and no quantity of these drugs was prescribed before selling at Veterinary pharmaceutical shops.
Conclusion: The regulation of Veterinary antibiotic prescription at veterinary pharmaceutical shops has to be a point of discussion and paid greater attention to ensure a sustainable control and reduction of transmission and spread of drug-resistant bacteria in humans and cattle.
Keywords: antibiotic prescription practice, antimicrobial resistance, Veterinary pharmaceutical shops
The role of the general practitioner in promoting organ donation
Authors: Jandou Issam , Rania Alafifi , Kbirou Adil , Mahmoud Alafifi , Moataz Amine , Dakir Mohammed , Debbagh Adil , Aboutaieb Rachid , Hassoune Samira 
Published: April 2022

Introduction: The effectiveness of a health system is based on primary care, the conductor of which is the general practitioner, who is also an integral part of the organ donation promotion chain. At present, as the indications for transplantation are more and more widespread, an immense shortage of organs is declared. This pushes more than ever to multiply creative tactics to reduce the gap between the number of high demand and stingy supply.
The main objective of this work is to particularize the involvement of the general practitioner in this process of encouraging donation, as well as to highlight his attitudes and his motivation during the consultation, and to identify the possible obstacles to the donation. Information and patient education on organ and tissue donation.
Material and method: A quantitative descriptive cross-sectional study, based on a questionnaire with 20 closed questions, self-administered, sent by email address, completed anonymously and voluntarily intended for the general practitioner of the region of Casablanca. Questionnaire data were collected, coded, and analyzed using SPSS-PC (Version 21.0).
Results: In total, 200 general practitioners were targeted by our study. 165 responded to the questionnaire, which gives an overall response rate of 82.5%. 35.5% of the participants were women, the duration of exercise varies between 1 and 40 years, 65% of the doctors practiced in the urban environment and approximately 59.5% worked in the liberal sector. 87% of the doctors questioned were in favor of organ donation. only 38% of doctors have already discussed this subject with their patients, of whom more than 64% were following the sole initiative of the patient himself and in none of the cases was awareness-raising through posters in the waiting room.
Conclusion: The general practitioner is a cornerstone of the success of public health programs. Continuous training of this category of doctors ensures better promotion of organ and tissue donation in Morocco.
Keywords: tissue donation, blood donation, donors and non-donors of the without, federating donors, Morocco
Comparative antimicrobial efficacy of ayurvedic formulations; Satva and Ghana of Tinospora cordifolia (Willd.) Miers (Giloy) against commensals and opportunistic pathogens
Authors: Javed Danish , Anwar Sana , Pathan Saman 
Published: April 2022

In our classical Ayurvedic texts, it has been described as beneficial in treating various types of diseases. Tinospora cordifolia satva (TCS) and Tinospora cordifolia ghana (TCG) is one of the unique Ayuvedic classical preparations, prepared from aqueous of extract of Giloy (Tinospora cordifolia Miers.) stem. These are frequently used medicines for the treatment of Madhumeha, Pandu, Kamala, Amlapitta, Grahani, Kustha, Jirna Jwara and Viswamjwara, Trishna, Shool, Yakritavikara, etc. Therefore, an attempt was made in this study to evaluate antimicrobial efficacy of these two dosage forms i.e. TCS and TCG. Enterococcus faecalis, Escherichia coli, Klebsiella pneumoniae and Propionibacterium acnes were used for antimicrobial evaluation and the classical method was used for the testing. The results shows that TCS can be considered as comparatively more potent antimicrobial than that of TCG at lower concentration on studied strains of E. coli, P. acnes.
Keywords: Guduchi satva, Guduchi ghana, Giloy, Tinospora cordifolia, anti-microbial activity, commensal pathogens
A Review on Pharmacological and Therapeutical Insight of Satranidazole for Colon Targeting in the treatment of Colonic Diseases
Authors: Ghosh Soumyadip , Ganguly Debgopal , Majumder Subhabrota , Chowdhury Ananta 
Published: April 2022

Drugs targeting the colonic environment to treat various colonic diseases are the major challenges recently. Various drugs are available in the markets to targeting to the colonic region to treat diseases but due to premature drug releases, target specificity, the low concentration at the target site with high adverse effects which increase patients’ compliance day by day. Satranidazole is a promising drug that is particularly targeting the colonic environment and can break down microorganism DNA to involve the treatment of several diseases such as inflammatory bowel diseases subdivided Ulcerative colitis, Crohn’s disease, amoebiasis, chronic diarrhea, and reduction of pain due to inflammation. Conventional drug delivery of Satranidazole has some disadvantages such as target specificity, high dosing frequency, low therapeutic efficacy, and high adverse effects that can be overcome through targeted drug delivery systems. Satranidazole is successfully showing the efficacy against aerobic, microaerophilic as well as anaerobic bacterial and reduction of inflammation of inflammatory bowel diseases subdivided as Ulcerative colitis and Crohn’s disease. It is a much more potent drug than metronidazole and has fewer adverse effects. Satranidazole is more convenient for oral administration compared to other routes of administration to show activity. Researchers are giving much more attention to targeted drug delivery systems of Satranidazole to show high therapeutic activity with fewer side effects. The current review focus on the pharmacological and therapeutical insight of Satranidazole in the treatment of colonic diseases and recent advancement and the future aspects of Satranidazole targeting various diseases.
Keywords: Satranidazole, Inflammatory bowel diseases, Ulcerative colitis, Crohn’s disease, Amoebiasis, Targeted drug delivery system, Future advancement, Colonic drug delivery systems.
The Use of Incision Wound Model to Improve the Clinical Skills of Nursing Students
Authors: Iriana Pramita 
Published: April 2022

Nursing education curriculum plays a significant role in preparing nursing graduates to begin clinical practice in the field. It is important to develop several learning methods, like skill-lab practice media, in order to enable students to practice more often before engaging in actual clinical practice and obtain a simulated picture that is close to reality. The objective of this research is to determine the effectiveness of a portable postoperative incision wound model on the clinical skills of nursing students. The quasi-experimental research method used pre and posttest evaluation in control and intervention groups. The intervention group used a portable incision wound care model during practice. Stratified random sampling was performed as a sampling method with 45 students in each group. The data were analyzed using dependent and independent t-tests, with a significance value of 0.05. All students scored above the passing grade limit (2.76). The mean difference among students using the portable wound care model increased by 0.31 and was higher than that in the control group, with an increase in the difference value by 0.26. The p value in both groups is 0.001
Keywords: Clinical skills, Portable wound model, Clinical skill-lab, Instructional media
Pengaruh Arus Kas, Profitabilitas dan Solvabilitas terhadap Financial Distress
Authors: Venisa Venisa , Widjaja Indra 
Published: April 2022

Penelitian ini bertujuan untuk mengetahui pengaruh arus kas, profitabilitas dan solvabilitas terhadap financial distress. Subjek penelitian ini adalah perusahaan sub-sektor perdagangan eceran yang terdaftar di Bursa Efek Indonesia tahun 2016-2019. Penelitian ini menggunakan sampel data sebanyak 68 data dari 17 perusahaan dan pemilihan sampel menggunakan purposive sampling. Teknik analisis data menggunakan teknik analisis regresi logistik. Data diolah dengan menggunakan Eviews 11. Hasil penelitian menunjukkan bahwa arus kas tidak berpengaruh terhadap financial distress, profitabilitas berpengaruh negatif terhadap financial distress dan solvabilitas tidak berpengaruh terhadap financial distress. This study aims to determine the effect of cash flow, profitability and solvability to financial distress. The subjects used in this study are retail trade sub-sector companies listed on the indonesian stock exchange in 2016-2019. This study used 68 data samples from 17 companies and sample selection using purposive sampling. Data analysis techniques using logistic regression analysis techniques. Data is processed using EViews 11. The results of this study indicate that cash flow not affecting financial distress, profitability negatively affecting financial distress and leverage not affecting financial distress.
Faktor Yang Mempengaruhi Nilai Perusahaan Pada Perusahan Manufaktur Yang Terdaftar Di BEI
Authors: Henryanto Wijaya Monica Melvi Reviani, 
Published: April 2022

This research aims to examine the effect of profitability, company size, company growth, and leverage to the firm value onmanufacturing companies that listed on Indonesia Stock Exchange for the period of 2015-2017. The samples of this research are sixty fivemanufacturing companies selected using purposive sampling method. The research data has been processed by using EViews 9.0. The result of this research shows that partially, profitability has a positive andnot significant influence to the firm value, company size has a positive and not significant influence to the firm value, company growth has a positive and not significant influence to the firm value, and leverage has a positive and not significant influence to the firm value
Pengaruh Ukuran Perusahaan, Profitabilitas, Leverage, Dan Kepemilikan Institusional Perusahaan Terhadap Nilai Perusahaan
Authors: Sufiyati Lani, 
Published: April 2022

This study aims to obtain empirical evidence on the effect of firm size, profitability, leverage, and institutional ownership of companies on firm value in manufacturing companies of consumption goods industry sectors listed in Indonesia Stock Exchange in the period 2015-2017. Research samples are 25 companies out of 42 companies data using purposive sampling method. Results of this research obtained the firm size have no effect to firm value, profitability have positive effect to firm value, leverage have no effect to firm value, and institutional ownership have no effect to firm value.
Faktor-Faktor Yang Mempengaruhi Income Smoothing Pada Perusahaan Manufaktur Di BEI
Authors: Ardiansyah Rasyid Hizkia Budiansyah, 
Published: April 2022

This study aims to understand the theory of firm size, financial leverage, institutional ownership, income smoothing, and to determine whether firm size, financial leverage, and institutional ownership partially and simultaneously affect income smoothing at manufacturing companies in Indonesia Stock Exchange (IDX) 2015-2017. Sampling using purposive sampling technique and total data used in this research is as many as 62 companies. The test results separately show partially financial leverage has a negative effect on income smoothing, while for firm size, and institutional ownership has no effect on income smoothing. Based on the test results simultaneously note that firm size, financial leverage, and institutional ownership simultaneously have an effect on income smoothing
PENGARUH INTELLECTUAL CAPITAL, FIRM SIZE, DAN LEVERAGE TERHADAP FINANCIAL PERFORMANCE
Authors: Thio Lie Sha Bartolomeus Thomas Ardianto, 
Published: April 2022

The purpose of this research is to analyze the predictive effect of Intellectual capital, Firm size and leverage on Financial Performance. The sample of this research is 65 manufacturing companies listed on the Indonesia Stock Exchange within the year 2015-2017. Application that is used in this research is Eviwews 9. The results of the t test in this research indicate that Human capital, structural capital and capital employed have a significant influence on Financial performance, meanwhile firm size and leverage does not have a significant effect on financial performance. Simultaneously, the results of the F test in this research show Human capital, structural capital and capital employed, Firm size and leverage have an significant influence on the financial performance.
FAKTOR-FAKTOR YANG MEMPENGARUHI REAL EARNINGS MANAGEMENT
Authors: Sufiyati Novita Cendra, 
Published: April 2022

This study aims to obtain empirical evidence on the effect of firm size, leverage, board size, board independence, audit comitee, cash flow from operation, and profitability of companies on real earnings management in manufacturing companies of basic industry and chemicals sector listed in Indonesia Stock Exchange in the period 2015-2017. Research samples are 21 companies out of 66 companies data using purposive sampling method. Results of this research obtained the firm size, leverage, and board size have no significant effect to real earnings management, board independence have positive significant effect, audit comitee haveno effect to real earnings management, cash flow from operation and profitability have negative significant effect to real earnings management.
PENGARUH PENGUNGKAPAN TATA KELOLA PERUSAHAAN, RETURN ON ASSET, LEVERAGE TERHADAP TAX AVOIDANCE YANG TERDAFTAR DI BEI
Authors: Estralita Trisnawati Felix Jonathan, 
Published: April 2022

The purpose of this study is to obtain empirical evidence on the effect of corporate governance, return on asset, leverage to tax avoidance that listed in Indonesia Stok Exchange, with a total of 46 samples. This study uses secondary data which were tested using software SmartPLS 3,0. The result of this study suggests that corporate governance and leverage does not significantly influence tax avoidance. However, return on asset have positive and significant influence tax avoidance.
PENGARUH PROFITABILITAS, STRUKTUR ASET, LIKUIDITAS DAN PERTUMBUHAN PENJUALAN TERHADAP STRUKTUR MODAL
Authors: Elizabeth Sugiarto Dermawan Viandy, 
Published: April 2022

The purpose of this research is to know the effect of profitability, tangibility, liquidity and sales growth on capital structure on manufacturing company listed on BEI from 2015-2017. This research used 141 observation that were selected using purposive sampling methodin three years. This research uses SPSS software version 23 to analysing the hypothesis. The result for this research showed that there is a negative and significant effect of liquidity on capital structure, however there is no significant effect of profitability, tangibility and sales growth.
FAKTOR – FAKTOR YANG MEMPENGARUHI NILAI PERUSAHAAN PADA PERUSAHAAN MANUFAKTUR
Authors: Rosmita Rasyid Devin Avila Dharma, 
Published: April 2022

The purpose of this research is to obtain empirical evidence about the effect of leverage, profitability, company growth, liquidity, firm size, audit committee on the firm value of manufacturing industries listed on the Indonesia Stock Exchange period 2015-2017. This study used 61 samples companies that have been selected through a purposive sampling method for three years. The data used were secondary data in the form of financial information from the financial statements. The research data was processed using Eviews 10. The results of the research showthatleverage, profitability, and firm size has an effect on firm value, while company growth, liquidity, and audit committee have no effect on firm value.
FAKTOR YANG MEMPENGARUHI NILAI PERUSAHAAN PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI
Authors: Rouilita Suhendah Rendy, 
Published: April 2022

The purpose of this study was to study the effect of liquidity, leverage, and profitability on firm value in manufacturing companies listed on the Indonesia Stock Exchange (IDX) in the period 2015-2017. This study used a non-probability sample method with a purposive sampling technique. The number of samples used in this study were 96 samples. The results of this study indicate that liquidity (CR) has a significant and negative effect on firm value, leverage (DAR) does not affect on firm value, and profitability (NPM) has a significant and positive effect on firm value. leverage (DAR), and profitability (NPM) together against company value.
FAKTOR YANG MEMPENGARUHI NILAI PERUSAHAAN DENGAN PROFITABILITAS SEBAGAI PEMODERASI PADA PERUSAHAAN MANUFAKTUR
Authors: Henryanto Wijaya Nathania Anastasia Sindunata, 
Published: April 2022

The purpose of this research is to analyze the effect of leverage, liquidity, devidend policy, and profitability as moderation variable to the firm value. Population on this research are manufacturing company listed on BEI from 2015 – 2017. Sampling technique in this research is using purposive sampling and 26 company within 3 years period and the result using 78 unit sample. To get the final result, researcher use Miscrosoft Excel2010 and software Eviews 10 program to produce panel data regression. Result of this research shows that leverage not significant negative on firm value, liquidity not significant negative on the firm value, dividend policy significant positive on the firm value, profitability not significant positive on the firm value,profitability is able to moderate leverage, liquidity, and dividend policy on the firm value.
PENGARUH KARAKTERISTIK PERUSAHAAN TERHADAP TINGKAT KEPATUHAN PENYAJIAN LAPORAN KEUANGAN SESUAI PSAK 1
Authors: Elsa Imelda Caroline Pujiono, 
Published: April 2022

The purpose of this study is to analyze of a firm’s characteristics, which include the profitability, industry type, and liquidityon the level of compliance in presenting financial statement based on PSAK 1 to the service firm registered in the Indonesian Stock Exchange on the period 2016-2018. The samples in this studytaken using a purposive sampling method. The data in this study is processed by Eviews 10.0, the result shows that the level of compliance in presenting financial statements based on PSAK 1 of Indoneisan companiesis82.55% in average. The regression analysis shows a significant relationship between industry type with the compliance level. The other independent variable, profitability and liquidityinsignificant on the compliance level based on PSAK 1.
FAKTOR - FAKTOR YANG MEMPENGARUHI PROFITABILITY PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA
Authors: Sofia Prima Dewi Novieany, 
Published: April 2022

The purpose of this thesis is to examine the effect of leverage, sales growth, firm size and working capital management on profitability in manufacturing companies listed on the Indonesia Stock Exchange. The sample selection technique in this study used a purposive sampling technique with a total sample of 27 manufacturing companies in the period 2015-2017. The data used in this study is secondary data which is processed using the program Eviews 9.0. The results of this study indicate that the size of the company has a negative influence on profitability while leverage, sales growth, and working capital management have no effect on profitability.
PENGARUH RELATED PARTY TRANSACTION TERHADAP TAX AVOIDANCE DENGAN VARIABEL MODERASI PENGUNGKAPAN TATA KELOLA PERUSAHAAN PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BURSA EFEK INDONESIA (BEI) PERIODE 2013-2017
Authors: Estralita Trisnawati Chindy Helfin, 
Published: April 2022

The purpose of this study is to obtain empirical evidence on the effect of related party transaction to tax avoidance with corporate governance disclosure as a moderating variable that listed in Indonesia Stok Exchange, with a total of 109 samples. This study uses secondary data which were tested using software SmartPLS 3,0. The result of this study suggests that related party transaction significantly influence tax avoidance. However, corporate governance disclosure doesn’t moderate the effect of related party transaction on tax avoidance.