bluuebunny/crossref_metadata_2025_split huggingface dataset:
“L’ENFANT ET LA VIE FAMILIALE SOUS L’ANCIEN RÉGIME” DE PHILIPPE ARIÈS: UNA ENTREVISTA SOBRE LA HISTORIA DE LA INFANCIA
Authors: Gómez Miguel , Alzate Piedrahita María Víctoria , Moreno Olaya Carol Shirley 
Published: September 2022

Nota de presentación

“Un libro tiene su propia vida, él escapa a su autor para pertenecer a un público que no es siempre aquel que el autor previó”, anotaba Philippe Ariès en el prefacio a la nueva edición de su obra L’enfant et la vie familiale sous l’Ancien Régime (Le Seuil, 1973, primera versión en Plon 1960), traducida al español veinte siete años después como: Philippe Ariès (1987). El niño y la vida familiar en el Antiguo Régimen. Madrid: Taurus. Versión castellana de Naty García Guadilla.
En este contexto, el lector hispanoamericano dispone a continuación de la traducción al español de un documento que consideramos fundamental para la comprensión de la historia de la infancia y la historia de las mentalidades, a saber: Jean-Bertrand. Pontalis y François Gantheret. Entretien avec Philippe Ariès. En: L’enfant. Publié sous la direction de Jean-Bertrand Pontalis. Paris. Gallimard, 1979. pp. 19-40.

La traducción de este documento complementa de primera mano un trabajo de reseña y recepción de la obra de Philippe Ariés, publicado con el título «Philippe Ariès: nacimiento, posteridad y vigencia de un modelo de interpretación de la infancia. Una revisión de la literatura historiográfica francófona». En: Alzate, M-V y Gómez, M.A. (Compiladores). Pensar la infancia I. Pereira-Colombia. Editorial Universidad Tecnológica de Pereira-Maestría en Infancia, 2020. pp. 127-139 (ver: https://repositorio.utp.edu.co/items/b06fcf25-944f-4a38-b9c7-99a1ad543257). Como anotábamos en el 2020, las tesis de la obra de Philippe Ariès: L’enfant et la vie familiale sous l’Ancien Régime siguen siendo sugerentes y actuales. La obra de Ariès nos muestra cómo la infancia es una construcción social relativamente reciente, sus tesis han permitido dar un lugar al niño y a la niña en la historia y las Ciencias Sociales. Las tesis del historiador francés implican un estatuto de la infancia que no puede ser pensado por fuera de la escuela y la familia, precisamente, esta fue la parte que asumió Ariès como de larga duración histórica para analizar la forma como aumentó, de manera paulatina y potente, el sentimiento familiar, sin el cual no es posible comprender la profunda “mutación antropológica” que constituye el nacimiento del “niño del deseo”; tal como se afirmó años después con la revolución de las condiciones de la procreación.
In vitro antitumor activity in breast cancer cells (SKBR3 and PMC42) of Ruta graveolens in homeopathic dilution
Authors: Valle Ana Catarina Viana , De Carvalho Aloísio Cunha , Brunel Hilana Dos Santos Sena , Rodrigues Maria Tereza de Oliveira , De Andrade Rosângela Vieira 
Published: September 2022

Objectives:
Given the need to establish less invasive treatments that improve the patient’s quality of life and still have antitumour effects, this study aimed to evaluate the behaviour of breast cancer tumour cells (SKBR3 and PMC42) by treatment with ultradiluted Ruta graveolens (Ruta D35).

Material and Methods:
The breast cancer cell lines SKBR3 and PMC42 were treated with ultradiluted Ruta D35 and the in vitro effects on cell viability was evaluated by MTT cytotoxicity assay.

Results:
In the SKBR3 cells, Ruta D35 at concentration of 8 μl/ml induced a significant reduction in cell viability when compared to the untreated control. The treatment with Ruta D35 in the PMC42 cells reduced cell viability from the treatment at the highest concentrations of 20 μl/ml, 30 μl/ml, 40 μl/ml and 50 μl/ml.

Conclusion:
Ruta D35 presented in vitro cytotoxic activity in SKBR3 and PMC42 breast cancer cells, thereby reducing cell viability. However, further tests are necessary to better understand the cytotoxic action and the potential of R. graveolens for treating breast tumour cells.
Data Mining Applications in Banking Sector While Preserving Customer Privacy
Authors: Doğuç Özge 
Published: September 2022

In real-life data mining applications, organizations cooperate by using each other’s data on the same data mining task for more accurate results, although they may have different security and privacy concerns. Privacy-preserving data mining (PPDM) practices involve rules and techniques that allow parties to collaborate on data mining applications while keeping their data private. The objective of this paper is to present a number of PPDM protocols and show how PPDM can be used in data mining applications in the banking sector. For this purpose, the paper discusses homomorphic cryptosystems and secure multiparty computing. Supported by experimental analysis, the paper demonstrates that data mining tasks such as clustering and Bayesian networks (association rules) that are commonly used in the banking sector can be efficiently and securely performed. This is the first study that combines PPDM protocols with applications for banking data mining. Doi: 10.28991/ESJ-2022-06-06-014 Full Text: PDF
Pembelajaran MBKM dengan Capaian Akhir Sistem E-commerce Platform (Benchmark OLX) di Binar Academy
Authors: Madani Ade Safarudin , Wiriasto Giri Wahyu , Misbahuddin  
Published: September 2022

Merdeka Belajar – Studi Independen merupakan salah satu kebijakan dari Menteri Pendidikan dan Kebudayaan mengenai mahasiswa dapat mengambil studi di luar kampus yang bertujuan untuk meningkatkan kompetensi yang sesuai dengan kebutuhan zaman. Melalui kegiatan MBKM Studi Independen di Binar Academy ini menjadi salah satu implementasi dalam tercapainya program Kemendikbud dalam membentuk mahasiswa yang mampu bersaing secara sosial, kerja sama, manajemen diri dan tuntutan kerja disaat pesatnya perkembangan zaman. Project case dilaksanakan di PT.Lentera Terang Benderang atau Binar Academy selaku mitra merupakan perusahaan bidang teknologi yang memfasilitasi pembelajaraan MBKM dengan metode bootcamp. Bootcamp berlangsung selama kurang lebih 5 bulan dilaksanakan dengan beberapa tahapan dan proses pembelajaran dilaksanakan secara synchronous dan asynchronous. Kegiatan akhir bootcamp dilaksanakan dengan pembuatan proyek akhir berupa sistem aplikasi E-commerce dengan benchmark OLX yang dapat digunakan sebagai transaksi jual beli barang bekas. Pengerjaan proyek akhir dengan Model Agile khususnya Scrum karena mampu merancang aplikasi yang scalable dengan waktu yang relatif singkat. Project akhir pengembangan Sistem berhasil dikembangkan sebagai sistem e-commerce situs jual-beli online khusus untuk menjual barang bekas.
Edukasi Masyarakat desa Tumpak Kecamatan Pujut Lombok Tengah Melalui Penyuluhan Budaya Hemat Energi dari Vampir Listrik
Authors: Muljono Agung Budi , I Made Ari Nrartha , Sultan Sultan , Tohri Muhamad , Paniran Paniran , Ginarsa I Made , Yadnya Made Sutha , Sasongko Sudi Mariyato Al 
Published: September 2022

Energi listrik merupakan salah satu kebutuhan manusia yang sangat penting dan vital yang tidak dapat dilepaskan dari keperluan sehari-hari. Tanpa disadari pada umumnya kebiasaan masyarakat dalam memperlakukan peralatan listrik/elektronik masih belum memperhatikan terhadap aturan standard baku. Salah satu perilaku kebiasaan yang kurang tepat apabila peralatan elektronik yang tidak digunakan, dalam posisi standby tetap dibiarkan terhubung ke stop kontak listrik. Hal ini dapat berpotensi menimbulkan bahaya panas dan pemborosan energi disebut vampire listrik. Desa Tumpak sebagai bagian kawasan KEK Mandalika maka peran serta masyarakat dalam program konservasi energi sangat diperlukan. Melalui kegiatan edukasi PKM telah terjadi peningkatan kemampuan peserta dari sisi teori dan praktik budaya hemat energi dari vampir listrik. Hasil evalusi pre-test dan pos-test terjadi peningkatan pemahaman dasar dan lanjut peserta sebesar 39,42%. Pada studi kasus pengukuran vampir listrik beban peralatan listrik/elektronik rumah tangga golongan tarif R-1/TR dengan daya 1300 VA, rerata konsumsi vampir listrik energy standby meyerap energi listrik sebesar 21,463344 kWh/bulan. Dengan edukasi ini maka dapat menghemat biaya sebesar Rp.32.195,00/bulan.
A longitudinal analysis of MPOWER implementation, 2008-2018
Authors: Hagen Les , Heydari Gholamreza , Hammal Fadi 
Published: September 2022

Background In 2008, the World Health Organization (WHO) introduced MPOWER-a package of evidence-based, high-impact policy measures to help countries reduce tobacco use. These measures align with selected articles within the World Health Organization’s Framework Convention on Tobacco Control (FCTC), a global public health treaty to prevent and reduce tobacco use. Methods Observational longitudinal study involving 195 countries that submitted biannual national reports between 2008 and 2018. To report changes in MPOWER scores, countries were assessed using a validated checklist of the seven MPOWER indicators and a maximum possible unweighted composite score of 34 points. Covariate analysis was conducted among selected health, sociopolitical, and economic indicators. Results 176 out of 195 countries improved their MPOWER scores between 2008 and 2018, with two achieving full implementation (Brazil and Turkey). Twenty-three (23) countries representing 11.2% of the global population recorded an MPOWER scoring increase of at least 10 points between 2008 and 2018. The overall mean 10-year scoring increase was 5.1 points or a relative improvement of 27.1%. In 2018, 20 countries representing 10.4% of the global population excelled in MPOWER implementation by receiving a total composite score of at least 30 of 34 possible points. The MPOWER elements with the highest degree of implementation in 2018 include Warn (package), Protect (smoking ban) and Enforce (ad ban). Several covariates were positively associated with higher levels of MPOWER implementation, including cigarette affordability, the existence of national tobacco control objectives, the human development index score, the national corruption index score, national literacy rates and the political regime index score. Conclusions MPOWER implementation increased markedly between 2008 and 2018 in all seven WHO regions and countries representing all four World Bank income classifications. However, only two countries achieved full implementation by 2018. More work is needed to improve MPOWER implementation. Countries with low-income levels, compromised human development, reduced literacy rates, higher rates of corruption, and autocratic political regimes appear to struggle more with MPOWER implementation.
The content of microand macroelements in the oral ﬂuid at different intensity of dental caries
Authors: Uspenskaya O. A. , Zhdanova M. L , Kostrova E. L. , Potekhina Yu. P. 
Published: September 2022

Introduction. Due to the high prevalence of caries, the monitoring of enamel and dentin state remains an actual problem in dentistry and contributes to the development of new methods for diagnosing and predicting a cariogenic situation in the oral cavity. One of these methods is the study of the remineralization and demineralization processes in the oral cavity and of the microelements′ and macroelements′ level in the oral ﬂuid.The aim of the study is to research the level of macroand microelements in the oral ﬂuid in patients with different intensity of dental caries.Materials and methods. 13 people aged 21 to 35 were examined, including 10 women and 3 men. Based on the results of the dental examination, 2 groups of subjects were formed: 1st (n=4) healthy individuals and patients with a compensated form of caries; 2st (n=9) patients with decompensated form of caries. The subjects collected oral ﬂuid by spitting into a test tube on an empty stomach, after brushing their teeth and rinsing their mouth three times with distilled water. Three samples were taken from each subject on different days, a total of 39 samples. The content of elements (Na, K, Ca, Mg, Fe, P, Mn) was determined by inductively coupled plasma atomic emission spectrometry.Results. An increase in the content of most microand macroelements (Na, K, Ca, Mg and P) in the oral ﬂuid was found in patients with decompensated caries compared with the compensated form and healthy people (p<0,05). Perhaps, in the absence of a carious process or compensated caries, the mineral components are concentrated in hard tissues and the remineralization-restoration processes of the tooth mineral structures prevail.Conclusion. The study of the content of Na, K, Ca, Mg and P in the oral ﬂuid can be used to diagnose and predict the course of the carious process.
Factores que inciden en el envejecimiento digno de los adultos mayores de la parroquia Santa Rosa– Ambato
Authors: Chango Andagana Martha María , Barahona Néjer Amílcar Alexander , Cárdenas Lata Bertha Janneth , Herrera Hugo Blanca de los Ángeles 
Published: September 2022

El objetivo de la investigación fue analizar las características de los factores que inciden en el envejecimiento de los adultos mayores en Ambato, para lograr este objetivo se utilizó el método descriptivo-analítico, los hallazgos encontrados se refieren a que los factores son diversos en función de las necesidades y carencias que tienen las personas que han llegado a esta etapa de sus vidas, ya que la realidad de un jubilado que cuenta con su pensión económica mensual no es igual a quienes no la poseen, y más aún a quienes viven el desarraigo de su familia, sin dejar de mencionar que a una precaria situación de vida de los mayores, generalmente se suman problemas serios de salud e incapacidades las cuales demandas significativos recursos que no están en posibilidades de solventar, por esta razón la corresponsabilidad que debe existir entre los organismos del Estado, sean estos nacional o locales, debe estar asociado a las atenciones del núcleo familiar más cercano al adulto mayor, un hallazgo importante de esta investigación explica los factores que inciden en un envejecimiento digno que encierran atención médica y psicológica, accesos seguros para una movilidad sin peligros, ingresos económicos necesarios para cubrir sus necesidades básicas y apoyo familiar para quienes tienen esta posibilidad.
Isolation of Viable Single Cells With High Yield and Purity Using a Small Amount of Human Kidney Tissue Biopsy
Authors: Yaigoub Hasnaa , Tirichen Hasna , Xin Xiaohong , Shi Shuhong , Wu Changxin , Li Rongshan , Li Yafeng 
Published: September 2022

Objective: Establishment of an efficient method of preparing human kidney single cell suspension, using a very small amount of tissue puncture.Methods: Samples of human kidney tissue puncture were cut into pieces, and then 80 μL of the digestive enzyme were added to each punctured tissue to induce enzymatic digestion. The enzyme combination is composed of collagenases, DNase and hyaluronidase and the sample was incubated 20 min at 37°C. The obtained cell suspension was filtered through a 70 μm cell strainer, centrifuged at 300 g for 5 min and the supernatant was removed, then the pellet was resuspended in 3 ml of DMEM (Dulbecco’s Modified Eagle’s Medium). Cell suspension was sorted and purified by flow sorting to remove dead cells and obtain a cell suspension with higher viability rate.Results: We found that 1) diverse single cells of human kidney can be obtained by the digestive enzyme, as observed under the light microscope, with different sizes, normal cell morphology and good dispersion. 2) (2-3) × 106 single cells can be extracted from one fresh punctured kidney tissue of about 10 mg, with a cell viability rate of more than 80%.Conclusion: In this work we generated a comprehensive and high-resolution single-cell method, which is simple and efficient for preparing single cell suspension from a minimal amount of human kidney tissue. This method can facilitate the study of renal cell biology and the pathogenesis of kidney diseases.
Electrochemically induced in vitro focal hypoxia in human neurons
Authors: Wong Joseph J. Y. , Varga Balazs V. , Káradóttir Ragnhildur Thóra , Hall Elizabeth A. H. 
Published: September 2022

Focalised hypoxia is widely prevalent in diseases such as stroke, cardiac arrest, and dementia. While in some cases hypoxia improves cellular functions, it mostly induces or exacerbates pathological changes. The lack of methodologies that can simulate focal acute hypoxia, in either animal or cell culture, impedes our understanding of the cellular consequences of hypoxia. To address this gap, an electrochemical localised oxygen scavenging system (eLOS), is reported, providing an innovative platform for spatiotemporal in vitro hypoxia modulation. The electrochemical system is modelled showing O2 flux patterns and localised O2 scavenging and hypoxia regions, as a function of distance from the electrode and surrounding flux barriers, allowing an effective focal hypoxia tool to be designed for in vitro cell culture study. O2 concentration is reduced in an electrochemically defined targeted area from normoxia to hypoxia in about 6 min depending on the O2-flux boundaries. As a result, a cell culture-well was designed, where localised O2 scavenging could be induced. The impact of localised hypoxia was demonstrated on human neural progenitor cells (hNPCs) and it was shown that miniature focal hypoxic insults can be induced, that evoke time-dependent HIF-1α transcription factor accumulation. This transcription is “patterned” across the culture according to the electrochemically induced spatiotemporal hypoxia gradient. A basic lacunar infarct model was also developed through the application of eLOS in a purpose designed microfluidic device. Miniature focal hypoxic insults were induced in cellular processes of fully oxygenated cell bodies, such as the axons of human cortical neurons. The results demonstrate experimentally that localised axonal hypoxic stress can lead to significant increase of neuronal death, despite the neurons remaining at normoxia. This suggests that focal hypoxic insult to axons alone is sufficient to impact surrounding neurons and may provide an in vitro model to study the impact of microinfarcts occurring in the deep cerebral white matter, as well as providing a promising tool for wider understanding of acute hypoxic insults with potential to uncover its pathophysiology in multiple diseases.
Clinical study on sequential treatment of severe diarrhea irritable bowel syndrome with precision probiotic strains transplantation capsules, fecal microbiota transplantation capsules and live combined bacillus subtilis and enterococcus faecium capsules
Authors: Lv Linling , Ruan Guangcong , Ping Yi , Cheng Yi , Tian Yuting , Xiao Zhifeng , Zhao Xuefei , Chen Dongfeng , Wei Yanling 
Published: September 2022

ObjectiveTo study the effect of precision probiotic strains transplantation capsules on diarrhea irritable bowel syndrome compared with fecal microbiota transplantation capsules and live combined bacillus subtilis and enterococcus faecium capsules.MethodsTwo patients with severe irritable bowel syndrome were treated with precision probiotic strains transplantation capsules, fecal microbiota transplantation capsules and live combined bacillus subtilis and enterococcus faecium capsules in sequence. IBS-SSS, IBS-QoL, GSRS, stool frequency, stool character, degree of abdominal pain, GAD-7, and PHQ9 scores of patients at 0, 2, 4, 6, 8, 10, and 12 weeks of treatment were monitored and recorded, and stool samples were collected for metagenomics and metabolomics.ResultsIt was found that the IBS-SSS score of patient case 1 decreased by 175 points and that of patient case 2 decreased by 100 points after treatment of precision probiotic strains transplantation capsules. There was no significant decrease after fecal microbiota transplantation capsules and live combined bacillus subtilis and enterococcus faecium capsules were used. At the same time, compared with fecal microbiota transplantation and live combined bacillus subtilis and enterococcus faecium capsules, the IBS QoL, stool frequency, stool character, degree of abdominal pain and GAD-7 score of patient case 1 improved more significantly by the precision probiotic strains transplantation capsules. And the stool frequency and stool character score of patient case 2 decreased more significantly. Intestinal microbiota also improved more significantly after the precise capsule transplantation treatment. And we found Eubacterium_ Eligens showed the same change trend in the treatment of two patients, which may play a role in the treatment.Conclusionprecision probiotic strains transplantation capsules is more beneficial to improve the intestinal microbiota of patients than microbiota transplantation capsule and live combined bacillus subtilis and enterococcus faecium capsules, so as to better alleviate clinical symptoms. This study provides a more perfect and convenient therapeutic drugs for the treatment of IBS.
The impact of UEFA Euro 2020 football championship on Takotsubo Syndrome: Results of a multicenter national registry
Authors: Polimeni Alberto , Spaccarotella Carmen , Ielapi Jessica , Esposito Giovanni , Ravera Amelia , Martuscelli Eugenio , Ciconte Vincenzo , Menichelli Maurizio , Varbella Ferdinando , Imazio Massimo , Navazio Alessandro , Sinagra Gianfranco , Oberhollenzer Rainer , Sibilio Gerolamo , Cacciavillani Luisa , Meloni Luigi , Dominici Marcello , Tomai Fabrizio , Amico Francesco , Corda Marco , Musumeci Giuseppe , Lupi Alessandro , Zezza Luigi , De Caterina Raffaele , Cernetti Carlo , Metra Marco , Rossi Lidia , Calabrò Paolo , Murrone Adriano , Volpe Massimo , Caldarola Pasquale , Carugo Stefano , Cortese Bernardo , Valenti Renato , Boriani Giuseppe , Fedele Francesco , Ventura Giorgio , Manes Maria Teresa , Colavita Angela Rita , Feola Mauro , Versaci Francesco , Assennato Pasquale , Arena Giuseppe , Ceravolo Roberto , Amodeo Vincenzo , Tortorici Gianfranco , Nassiacos Daniele , Antonicelli Roberto , Esposito Nicolino , Favale Stefano , Licciardello Giovanni , Tedesco Luigi , Indolfi Ciro 
Published: September 2022

ObjectivesThe UEFA 2020 European Football Championship held in multiple cities across Europe from June 11 to July 11, 2021, was won by Italy, providing an opportunity to examine the relationship between emotional stress and the incidence of acute cardiovascular events (ACE).Methods and resultsCardiovascular hospitalizations in the Cardiac Care Units of 49 hospital networks in Italy were assessed by emergency physicians during the UEFA Euro 2020 Football Championship. We compared the events that occurred during matches involving Italy with events that occurred during the remaining days of the championship as the control period. ACE was assessed in 1,235 patients. ACE during the UEFA Euro 2020 Football Championship semifinal and final, the most stressful matches ended with penalties and victory of the Italian team, were assessed. A significant increase in the incidence of Takotsubo Syndrome (TTS) by a factor of 11.41 (1.6–495.1, P &lt; 0.003), as compared with the control period, was demonstrated during the semifinal and final, whereas no differences were found in the incidence of ACS [IRR 0.93(0.74–1.18), P = 0.57]. No differences in the incidence of ACS [IRR 0.98 (0.87–1.11; P = 0.80)] or TTS [IRR 1.66(0.80–3.4), P = 0.14] were found in the entire period including all matches of the UEFA Euro 2020 compared to the control period.ConclusionsThe data of this national registry demonstrated an association between the semifinal and final of UEFA Euro 2020 and TTS suggesting that it can be triggered by also positive emotions such as the victory in the European Football Championship finals.