bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Kentucky's Local Health Department Cross-Jurisdictional Sharing: Strategy for Maximizing Efficiency
Authors: Carman Angela L. , Gatton Kelsey , Hogg-Graham Rachel 
Published: August 2022

Objective:
The purpose of this study was to examine patterns of cross-jurisdictional sharing across the 61 local public health jurisdictions (LHJs) in Kentucky. The opportunities to reduce the cost-of-service delivery for Kentucky's LHJs via cross-jurisdictional sharing present a mechanism to address financial instability across the state by achieving economies of scale, especially among smaller jurisdictions.

Design:
A cross-sectional study design was used to examine patterns of cross-jurisdictional sharing across the 61 LHJs in Kentucky. The survey tool utilized was designed by the Center for Sharing Public Health Services, an initiative managed by the Kansas Health Institute with support from the Robert Wood Johnson Foundation.

Results:
Seventy-two percent of the 61 LHJs in Kentucky responded to the survey. The majority of responding jurisdictions sharing services were rural, single-county jurisdictions, utilizing service-related informal sharing arrangements. The majority of health departments, when asked to identify which programmatic areas shared service arrangements were focused in, listed those services requiring intensive staff training such as Health Access Nurturing Development Services (HANDS) and epidemiology. Of particular interest were the services most infrequently shared such as communicable disease screening and treatment.

Conclusions:
This study suggests that, pre-COVID-19, a core group of primarily rural, single-county Kentucky local health departments has experience with cross-jurisdictional sharing. Among this group, engagement in informal arrangements was the form of cross-jurisdictional sharing predominantly used, with few jurisdictions reporting shared functions with joint oversight. When considering the potential benefits and efficiencies that cross-jurisdictional sharing can provide to public health departments and their communities, for some, COVID-19 may have been a catalyst to engage in sharing across health department jurisdictional lines.
Cognitive screening in persons with an amputation: A retrospective medical record audit
Authors: Dawes Erinn , Bliokas Vida , Hewitt Lyndel , Wilson Val 
Published: August 2022

Objective:
To determine the rate of cognitive screening undertaken with patients undergoing amputation and to determine the demographics of the sample.

Study design:
Retrospective medical record audit.

Methods:
The medical records of a convenience sample of persons who had undergone amputation, upper and lower limb, from one local health district were reviewed. The sample date range was between January 1st, 2017, and December 31st, 2018. The incidence and type of cognitive screening were also recorded. Descriptive statistics were used to describe the results.

Results:
A total of 178 episodes of amputation care were identified during retrospective medical record auditing (mean age, 69.7 years). Thirty nine of the 178 (21.9%) episodes of care had a cognitive screening measure completed during that inpatient admission (24.2% vascular etiology and 12% nonvascular etiology). All cognitive screens were completed in persons with lower-limb amputations and were completed postoperatively.

Conclusion:
Cognitive screening is not a routine part of the health care journey for patients with an amputation in this health care district.
3D-printed medial arch supports of varying hardness versus a prefabricated arch support on plantar pressure: A 1-month randomized crossover study in healthy volunteers
Authors: Channasanon Somruethai , Praewpipat Bongkoch , Duangjinda Nitkamon , Sornchalerm Lertchai , Tesavibul Passakorn , Paecharoen Siranya , Tanodekaew Siriporn 
Published: August 2022

Background:
Foot orthoses are commonly used as a noninvasive treatment to relieve foot pain. The custom full-length insoles with various materials and designs have been studied for their effectiveness in reducing plantar pressure. However, few studies have been conducted with respect to custom medial arch support on the relationships between material hardness and measured plantar pressure and level of comfort.

Objectives:
To evaluate the effects of the hardness of custom medial arch supports on plantar pressure and comfort perception.

Study design:
Randomized crossover study.

Methods:
Two custom silicone medial arch supports of varying hardness (A and B) were fabricated using 3D printing technology and tested in 12 healthy volunteers against a commercially prefabricated arch support (C). The volunteers wore three medial arch supports in a random order, one month for each arch support with 3–4 days of washout period before wearing the next one. The plantar pressure was measured and analyzed according to each foot zone: forefoot, midfoot, and hindfoot, comparing before intervention, immediately after intervention, and 1 month after intervention. The comfort perception was assessed by collecting volunteer feedback with a questionnaire after using each medial arch support.

Results:
After 1-month intervention, both 3D-printed and prefabricated medial arch supports demonstrated significantly higher average pressure in the midfoot (P < 0.001), whereas significantly lower average pressure in the forefoot (P < 0.001) and hindfoot (P = 0.014, 0.026, and 0.018 for A, B, and C, respectively), compared with those before intervention. There were no significant differences in plantar pressure distribution between the 3D-printed and prefabricated medial arch supports. However, the 3D-printed medial arch supports resulted in better comfort than the prefabricated arch support.

Conclusions:
The material hardness had no apparent effect on plantar pressure distribution. The three medial arch supports showed reducing plantar heel pressure. Further research is needed to investigate the potential effect of 3D-printed silicone medial arch supports on reducing foot pain in patients.
Determination of the Anthropometric Measures of the Lips by Age Groups in the Mestiza Population
Authors: Serrano-Andrade J. David , Apellaniz-Campo Armando , Ramírez-Fernández Francisco J. , Castillo-Moreno Julio , Morales Jesus M. , Gómez Karen C. , Alvarado Pedro A. 
Published: August 2022

Measurements from a certain population may show a similar pattern that allows an alteration to be easily recognized and enable a better surgical approach. In our population, the changes in the anthropometric measurements of the lips are unknown, so our objective is to determine the variations in these measurements by decades of age to achieve a better aesthetic and reconstructive surgical approach. Anthropometric measurements of the lips were taken with a vernier in relation to the previously marked anatomical points. The sample consists of 174 patients who came for care not related to labial pathologies with ages between 20 and 80 years with Mexican nationality. We use the sample calculation formula to estimate an average, with an alpha error of 0.5 and a tolerance of 2 mm of the data for the measurements of the height of the lower face with an average measurement of 56.2 mm and a SD of 8.87 mm of the Marzena’s article. Wyganowska-Świątkowska and colleagues Average measurements were obtained, where a progressive longitudinal increase in measures: al-ch, sbl-cph, sn-Is, li-sto, cph-Is, li-sl, ch-li, li-pg according to aging is confirmed. In contrast, the ch-cph and ch-sbl measures, remain the same despite the aging, showing greater changes in the sagittal plane than in the parasagittal. The study only shows measures of length, so caring out a magnetic resonance imaging study to also measure the volume and perform it with a larger sample to have the optimal standard is further needed.
Gastric glomus tumor in a patient with biliary colic: a rare case report with literature review
Authors: Abdulla Karzan S. , Kaka Ali Hemn H. , Hassan Hemin A. , Ismaeil Deari A. , Ghalib Hawramy Omar H. , Salih Abdulwahid M. , Naqar Sharo , Abdulla Berun A. , Kakamad Fahmi H. 
Published: August 2022

Introduction:
Glomus tumor (GT) mainly occurs in the extremities. Its appearance elsewhere has rarely been reported. This study aims to report an incidental finding of gastric GT in a patient with biliary colic.

Case presentation:
A 45-year-old female presents with moderate to severe upper abdominal pain. Physical examination was performed, the abdomen was soft, nontender, and no mass felt. Transabdominal ultrasound showed a single stone in the gallbladder, normal wall thickness, and no biliary dilatation. The diagnosis of biliary colic was achieved based on the clinical presentation, examination findings, and test results. Wedge resection of the stomach with open cholecystectomy was performed. Histopathology result was compatible with gastric GT.

Clinical discussion:
The clinical examination of GT is much similar to other tumors like hemangioma, lipoma, gastrointestinal stromal tumor, and leiomyoma. Concerning diagnosis, GT is mostly intersecting with gastrointestinal stromal tumors, mainly in small biopsy screening. For this reason, most of the gastric GT can be identified preoperatively as gastrointestinal stromal tumors.

Conclusion:
Gastric GT is an uncommon benign tumor that can be found incidentally during the diagnosis of other diseases or tumors because of its clinical and radiologic similarities.
Predatory journals in oncology: prevalence and impacts
Authors: Mohammed Shvan H. , Kakamad Fahmi H. , Salih Abdulwahid M. , Omar Diyar A. , Mikael Tomas M. , Hassan Marwan N. , Aziz Masrur S. , Baba Hiwa O. , Abdullah Hiwa O. , Mustafa Mohammed Q. , Essa Rawand A. , Kakamad Suhaib H. , Qadr Goran A. , Othman Snur , Salih Rawezh Q. , Abdulla Fakher , Abdulla Berwn A. , Najar Kayhan A. , Hussein Dahat A. , Sidiq Shadi H. , Rahim Hawbash M. , Mohammed Karokh K. , Ali Rebwar A. , Ahmed Jaafar O. , Hammood Zuhair D. 
Published: August 2022

Objectives:
The aim of this report is to determine and present the prevalence and impact of predatory journals and publishers in the field of oncology.

Method:
All predatory journals specific to oncology were included in this study. The reference list was Kscien’s list.

Results:
Two hundred fifty-eight predatory oncology journals were identified. They distributed 33,069 papers. These publications have received 335,217 citations with a mean of 1250.81 citations per journal and 10.14 citations per paper. The majority of these citations (300,259, 89.57%) came from the legitimate journals. About 235,586 coauthors from 141 countries have published one or more articles in these journals.

Conclusion:
The huge number of papers and citations are a threatening alarm. Oncologists and oncology researchers must learn how to avoid these journals.
Musical Bridges to Memory
Authors: Schafer Rhiana , Karstens Aimee , Hospelhorn Emma , Wolfe Jeffrey , Ziemba Amanda , Wise Peggy , Crown Rickie , Rook Jenni , Bonakdarpour Borna 
Published: August 2022

Background:
Music-based psychosocial interventions may provide effective management of behavioral symptoms in persons with dementia (PWDs). However, there has been a paucity of studies that measured their effect on social engagement. This proof-of-concept study evaluates efficacy of the Musical Bridges to Memory (MBM) intervention on PWD’s social engagement, behavioral symptoms, and associated caregiver distress.

Methods:
Twenty-nine PWDs and caregivers (8 control dyads, 21 intervention) participated in this dyadically designed, prospective, blinded, 12-week controlled interventional study. The intervention consisted of weekly MBM sessions, led by board-certified music therapists and performers, including caregiver training, live performances, and social breakout groups. Outcomes were measured by the Verbal and Nonverbal Interaction Scale for Care Receivers (VNVIS-CR) to code interactions between PWDs and caregivers for verbal and nonverbal sociable and unsociable behaviors. Symptom severity and caregiver distress were measured using Neuropsychiatric Inventory.

Results:
Nonverbal sociable interactions significantly increased (P=0.012) in those who completed the MBM program as compared with a decrease observed in the control group. Family/caregiver distress associated with PWDs neuropsychiatric symptoms showed significant improvement in the experimental group as compared with controls (P=0.045).

Conclusions:
This study provides proof-of-concept that MBM improves nonverbal sociable content of PWDs interactions and reduces caregivers’ distress.
Modelling brain tissue elasticity with the Ogden model and an alternative family of constitutive models
Authors: Anssari-Benam Afshin , Destrade Michel , Saccomandi Giuseppe 
Published: August 2022

The Ogden model is often considered as a standard model in the literature for application to the deformation of brain tissue. Here, we show that, in some of those applications, the use of the Ogden model leads to the non-convexity of the strain-energy function and mis-prediction of the correct concavity of the experimental stress–stretch curves over a range of the deformation domain. By contrast, we propose a family of models which provides a favourable fit to the considered datasets while remaining free from the highlighted shortcomings of the Ogden model. While, as we discuss, those shortcomings might be due to the artefacts of the testing protocols, the proposed family of models proves impervious to such artefacts.
This article is part of the theme issue 'The Ogden model of rubber mechanics: Fifty years of impact on nonlinear elasticity'.
Exponents of the one-term Ogden model: insights from simple shear
Authors: Horgan Cornelius O. , Murphy Jeremiah G. 
Published: August 2022

Isotropic one-term Ogden models are widely used to predict the mechanical response of both incompressible elastomers and soft tissue. Even though the exponent might be chosen to yield excellent agreement with some aspects of mechanical response, there is no guarantee that these models will be physically realistic in all situations. We show here that, in particular, the predictions of models with either negative or large positive exponents do not seem physically realistic in simple shear. The mechanical response of materials in shear should be physically realistic to ensure rational and reliable predictions for complex geometries and boundary conditions. We suggest that for problematic values of exponents of one-term models that extra Ogden invariants should necessarily be included in the model.
This article is part of the theme issue ‘The Ogden model of rubber mechanics: Fifty years of impact on nonlinear elasticity’.
An introduction to the Ogden model in biomechanics: benefits, implementation tools and limitations
Authors: Lohr Matthew J. , Sugerman Gabriella P. , Kakaletsis Sotirios , Lejeune Emma , Rausch Manuel K. 
Published: August 2022

Constitutive models are important to biomechanics for two key reasons. First, constitutive modelling is an essential component of characterizing tissues’ mechanical properties for informing theoretical and computational models of biomechanical systems. Second, constitutive models can be used as a theoretical framework for extracting and comparing key quantities of interest from material characterization experiments. Over the past five decades, the Ogden model has emerged as a popular constitutive model in soft tissue biomechanics with relevance to both informing theoretical and computational models and to comparing material characterization experiments. The goal of this short review is threefold. First, we will discuss the broad relevance of the Ogden model to soft tissue biomechanics and the general characteristics of soft tissues that are suitable for approximating with the Ogden model. Second, we will highlight exemplary uses of the Ogden model in brain tissue, blood clot and other tissues. Finally, we offer a tutorial on fitting the one-term Ogden model to pure shear experimental data via both an analytical approximation of homogeneous deformation and a finite-element model of the tissue domain. Overall, we anticipate that this short review will serve as a practical introduction to the use of the Ogden model in biomechanics.
This article is part of the theme issue ‘The Ogden model of rubber mechanics: Fifty years of impact on nonlinear elasticity’.
Genetic Architecture of Heart Mitochondrial Proteome influencing Cardiac Hypertrophy
Authors: Krishnan Karthickeyan Chella , El Hachem Elie-Julien , Carroll Luke , Vegas Alexis Diaz , Light Christine , Cao Yang , Pan Calvin , Kaczor-Urbanowicz Karolina Elżbieta , Shravah Varun , Anum Diana , Pellegrini Matteo , Lee Chi Fung , Seldin Marcus M. , Parker Benjamin L. , James David E. , Lusis Aldons J. 
Published: August 2022

ABSTRACTMitochondria play a key role in the normal function of the heart as well as in the pathogenesis of diseases. We report analysis of common genetic variations contributing to mitochondrial and heart functions using an integrative proteomics approach in a panel of inbred mouse strains called the Hybrid Mouse Diversity Panel (HMDP). We performed a whole heart proteomic analysis in the HMDP (72 strains, n=2-3 mice) and retrieved 840 mitochondrial proteins (quantified in ≥50 strains). High-resolution association mapping on their respective abundance levels identified three trans-acting genetic loci, located on chromosome (chr) 7, chr13 and chr17, that control distinct classes of mitochondrial proteins as well as heart hypertrophy. Follow-up high resolution regional mapping identified NDUFS4, LRPPRC and COQ7 as the candidate genes for chr13, chr17 and chr7 loci, respectively, and both experimental and statistical analyses supported their causal roles. Variations of all three were associated with heart mass in two independent heart stress models, namely, isoproterenol (ISO)-induced heart failure and diet-induced obesity (DIO) models. To identify the aspects of mitochondrial metabolism regulated by these loci, we constructed co-expression protein networks using weighted gene co-expression network analysis (WGCNA). DAVID enrichment analyses of genes regulated by each of the loci revealed that the chr13 locus was highly enriched for complex-I proteins (24 proteins, P = 2.2E-61), the chr17 locus for mitochondrial ribonucleoprotein complex (17 proteins, P = 3.1E-25) and the chr7 locus for ubiquinone biosynthesis (3 proteins, P = 6.9E-05). These results indicate that common variations of certain mitochondrial proteins can act in trans to influence mitochondrial functions and contribute to heart hypertrophy, elucidating mechanisms that may underlie genetic susceptibility to heart failure in human populations.
Synchrotron-based DEI and DEI-CT systems to image chick pea seeds, plant anatomy and the associated physiology at 30 keV
Authors: Rao D.V. , Gigante G.E. , Zhong Z. , Cesareo R. , Brunetti A. , Schiavon N. , Akatsuka T. , Yuasa T. , Takeda T. 
Published: August 2022

SummaryThe study the effect of contrast on seeds, growth and the associated anatomy and physiology, with upgraded imaging systems. The use of phase information to explore new information at various stage of the growth.This work benefits, the use of Synchrotron-based DEI and DEI-CT systems to enhance the contrast in plant root architecture and contrast mechanisms, visibility of fine structures of root architecture growth and some aspects of physiology at acceptable level. These non-destructive, imaging systems available at the X-15A beamline, at NSLS, BNL, USA, are utilized.Noticed detailed anatomical and physiological observations, contrast mechanisms, with these upgraded systems, compared to other conventional techniques, equipped with tube source of X-rays. Examined the potential of these systems to quantify the plant roots in situ. The acquired images provided good contrast, anatomical structures and physiology of the plant root micro-architecture. We observed some of the complex plant traits, such as growth, development, root architecture and the associated physiology. The interior structure, root architecture, root morphology, growth of laterals and subsequent laterals can be visualized directly by synchrotron-based imaging techniques.Root architecture of the plant grown from seeds provides new information about the structure and enhancement of some desired property, for example, interior micro-structure of the root laterals and the subsequent laterals and the clear visibility of the leaves in detail. This way, it will be possible to differentiate the weakly and strongly attenuation of the signal traversing within the sample, clearly reflects the acceptable visibility in root laterals, subsequent laterals and the associated opaque matrix with enhanced contrast. The sample has a thin layer of hard structure outside and protein inside. Extinction properties of these samples will be characterized by Sy-DEI and Sy-DEI-CT. This way, we may be able to differentiate softly and weakly attenuation within the sample, to know more about the contrast mechanisms. The visibility, contrast and porosity, with finer details, can be noticed, with Sy-DEI-CT systems as distinguished from Sy-DEI. However, limited field of view, may limit the problems associated with Sy-DEI-CT.
Fibrillin microfibril structure identifies long-range effects of inherited pathogenic mutations affecting a key regulatory TGFβ-binding site
Authors: Godwin Alan RF , Thomson Jennifer , Holmes David F , Adamo Christin S , Sengle Gerhard , Sherratt Michael J , Roseman Alan M , Baldock Clair 
Published: August 2022

AbstractGenetic mutations in fibrillin microfibrils cause a range of serious inherited diseases such as Marfan syndrome (MFS) and Weill-Marchesani syndrome (WMS). These diseases typically show major dysregulation of tissue development and growth, particularly in skeletal long bones, but links between the mutations and the diseases are unknown. In this study we reveal the detailed cryo-EM structure of native fibrillin microfibrils from mammalian tissue. The major bead region showed pseudo 8-fold symmetry and a buried protease resistant N-terminal core. Based on this structure, we show a WMS deletion mutant induces a rearrangement with long-range effects blocking interaction with latent TGFβ-binding protein (LTBP)-1 at a remote site. Separate deletion of this binding site resulted in the assembly of shorter fibrillin microfibrils with structural alterations. These results establish that in complex extracellular protein assemblies, such as in fibrillin, mutations may have long-range structural consequences to disrupt growth factor signalling and cause disease.