bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combining reconstructive and ablative surgical treatment of chronic breast cancer-related lymphedema (BCRL): safe and effective
Authors: Ghazaleh Alina A. , Handschin Tristan M. , Buckowiecki Julia , Chammartin Frédérique S. , Andree Christoph , Schaefer Dirk J. , Haug Martin , Kappos Elisabeth A. , Seidenstuecker Katrin 
Published: October 2022

Abstract
Purpose
We investigated whether a one-stage combination of vascularized lymph node transfer (VLNT) with water jet-assisted liposuction (WAL) can be safely performed and results in improved patient outcomes such as a greater reduction in arm volume when treating chronic breast cancer-related lymphedema (BCRL).

Methods
In this retrospective cohort study, we included all patients from our encrypted lymphedema database treated for chronic BCRL with VLNT or VLNT + WAL who had a minimum follow-up of two years. We analyzed patient-specific variables including arm circumferences as well as patient-reported outcomes before and after surgery as well as surgery time, surgery-related complications and patient satisfaction.

Results
Only the mean preoperative differences of the circumferences between the lymphedematous and the unaffected arm in individual patients showed a statistically significant difference between treatment groups (p < 0.05). Indeed, patients treated with VLNT + WAL had consistently larger differences in individual sets of arms and therefore more pronounced chronic BCRL. The mean surgery time was significantly longer in the VLNT + WAL group (p < 0.05). Complications were seldom and similar in both groups. Using a numeric rating scale, the level of patient satisfaction following treatment did not differ significantly between groups (p = 0.323).

Conclusions
Our findings suggest that a one-stage combination of VLNT with WAL does not result in more complications even though it also entails a longer surgery time. This is acceptable as secondary interventions resulting in overall longer surgery times and higher costs can be avoided. A one-stage combination might be especially favourable for patients suffering from more severe chronic BCRL.
Composite membranes of cellulose–mesoporous silica: optimization of membrane fabrication and adsorption capacity
Authors: Miri Simin , De Girolamo Anthony , Nadeem Humayun , Chin Benjamin Wey Xien , Hora Yvonne , Andrews Philip C. , Batchelor Warren 
Published: October 2022

AbstractIn this work, we produced composites of mesoporous silica synthesized in-situ on never-dried bleached eucalyptus kraft pulp fibers with the aim of providing cost-effective depth filters, having high flux, and adsorptivity. The mesoporous silica loading for the produced samples was in the range of 12–35 wt%. The performance of double-layer membranes was studied for the adsorption of charged molecules. The best nanofibrillated cellulose-pulp-mesoporous silica membrane adsorbed 1160 mg/m2 of methylene blue and had a flux of 10 L m−2 h−1 bar−1. The nanofibrillated cellulose layer supported the pulp-mesoporous silica layer and improved the adsorptivity of the pulp-mesoporous silica depth filter layer by controlling flux. The membranes showed non-linear-pseudo-first-order adsorption kinetics and non-linear Freundlich isotherm for methylene blue adsorption. The nanofibrillated cellulose-pulp-mesoporous silica membrane was modified for metanil yellow adsorption by adding polyamide amine-epichlorohydrin resin. The best metanil yellow saturated adsorption capacity was 9400 mg/m2. The nanofibrillated cellulose-pulp-mesoporous silica depth filter without modification with a polyelectrolyte also had 92% and 94% heavy metal removal of 20 mg of Cu2+ and Pb2+ ions, respectively. The novel pulp-mesoporous silica composite membrane, with high adsorption capacity and manufactured by lower embodied energy of cellulose fiber, can significantly lower large-scale depth filter production costs due to the elimination of cellulose pre-treatment for the depth filter layer. The reusability performance in the fifth cycle, after four cycles of metanil yellow adsorption and desorption, was 5.2 mg/g, which was stabilized from the 3rd to 5th cycles. This suggests the suitability of these membranes for industrial applications.
Bidirectional hybridisation and introgression between introduced European brown hare, Lepus europaeus and the endemic Irish hare, L. timidus hibernicus
Authors: Reid Neil , Hughes Maria F. , Hynes Rosaleen A. , Montgomery W. Ian , Prodöhl Paulo A. 
Published: October 2022

AbstractIntroduced non-native species can threaten native species through interspecific hybridisation and genetic introgression. We assessed the prevalence of hybridisation and introgression between introduced European brown hare, Lepus europaeus, and the endemic Irish hare, L. timidus hibernicus. Roadkill hares (n = 56) were sequenced for a 379bp section of the mitochondrial DNA D-loop and a 474bp segment of the nuclear transferrin (Tf) gene. A species-specific indel in the transferrin gene was present in L.t. hibernicus and absent in L. europaeus. Excluding three hares from which molecular data could not be recovered, 28 hares (53%) were native L.t. hibernicus, 7 (13%) were non-native L. europaeus and 18 (34%) were hybrids; of which 5 (28%) were first generation (F1) involving bidirectional crosses with mismatched nuclear and mtDNA (3 ♂ europaeus x ♀ hibernicus and 2 ♂ hibernicus x ♀ europaeus). Mixed nuclear transferrin sequences suggested 13 (72%) of hybrids were at least 2nd generation (F2) with 9 (69%) possessing L.t. hibernicus and 4 (31%) L. europaeus mtDNA (the latter indicative of hybrid backcrossing with the non-native). The prevalence of hybridisation at similar mountain-brown hare contact zones throughout Europe is notably lower (4–16%) and typically unidirectional (♂ europaeus x ♀ timidus). A high prevalence of bidirectional hybridisation and introgression (in association with projected climate change) may favour the introduced species over the native. Genetic surveillance and population monitoring are needed to further explore the potential conservation implications of European brown hare in Ireland.
Early right ventricular dysfunction after primary percutaneous coronary intervention in anterior versus isolated inferior myocardial infarction assessed by tissue Doppler imaging and speckle tracking echocardiography
Authors: Radwan Hanan Ibrahim , Alhoseeny Ahmed Mostafa Abdelhaleem , Ghoniem Salwa Mohamed , Nashy Baher Nabil Eldesouky , Shehata Islam Elsayed 
Published: October 2022

AbstractThis study hypothesized that imaging provides information indicating the right ventricular (RV) involvement after anterior or inferior ST-elevation myocardial infarction (STEMI), beyond standard electrocardiogram (ECG) due to the increasing interest in RV function and assessment techniques. This study aimed to compare RV function between anterior and inferior MI without RV involvement using different echocardiographic modalities. This study included 100 patients with anterior (50 patients) and inferior (50 patients) STEMI, who underwent primary percutaneous coronary intervention (PPCI) and two-dimensional echocardiographic imaging within 24 h after PPCI with RV function analysis by left ventricular (LV) infarct size, LV filling pressure, and RV strain rate. Our primary endpoint was the subclinical RV dysfunction in anterior or inferior MI using tissue Doppler and speckle tracking (STE). The study population included 80 (80%) males and 20 (20%) females. Patients with the anterior STEMI had higher mean creatine kinase-MB (CKMB) and troponin than those with inferior STEMI. This study revealed worse RV dysfunction in patients with anterior than those with inferior STEMI, as reflected by significantly lower RV systolic function, tricuspid annular plane systolic excursion (p ≤ 0.0001), tissue Doppler-derived velocity (p ≤ 0.0001), and STE-derived strain magnitude and rate (p ≤ 0.0001). RV dysfunction occurs in patients without ECG evidence of RV STEMI. RV dysfunction is worse in anterior than inferior MI. Moreover, RV systolic functions were affected by declined LV ejection fraction irrespective of the infarction site, which clinically implies prognostic, treatment, survival rate, and outcome improvement between both conditions. (Trial registration ZU-IRB#:4142/26–12-2017 Registered 26 December 2017, email: IRB_123@medicine.zu.edu.eg).
Indigenous Knowledge, Aspiration, and Potential Application in Contemporary Fire Mitigation in Southwest Australia
Authors: Rodrigues Ursula , Lullfitz Alison , Coyne Lester , Dean Averil , Eades Aden , Flowers Ezzard , Knapp Lynette , Pettersen Carol , Woods Treasy , Hopper Stephen D. 
Published: October 2022

AbstractProtection of biodiversity, human assets, and cultural heritage pose significant challenges to contemporary planning of bushfire mitigation activities. Current mitigation approaches are not always appropriate, and mismanagement is a source of distress for Indigenous peoples. Increased understanding of Indigenous fire knowledge and increased Indigenous participation may provide insight into more appropriate and inclusive land management for fire mitigation. We analysed contemporary Noongar and Western fire practitioner approaches within an Indigenous fire knowledge (IFK) framework to explore knowledge and aspirations for small reserves in the Southwest Australian Floristic Region (SWAFR) global biodiversity hotspot. We recorded an extensive knowledge base, characterised by a highly nuanced approach to burning, held by the Noongar coauthors. We explore potential approaches to applying this knowledge to build collaborative fire mitigation strategies with mutually beneficial outcomes for biodiversity, cultural heritage, and human assets.
First releases of hatchery-produced Senegal sole (Solea senegalensis), brill (Scophthalmus rhombus), and wedge sole (Dicologoglossa cuneata) juveniles in the South-western Spanish coast
Authors: Herrera Marcelino , Rodiles Ana , Salamanca Natalia , Navas Jose Ignacio , Cordero María Luisa , Hachero Ismael 
Published: October 2022

AbstractThe regression of fisheries in the Gulf of Cadiz is evident since current fish catches are 33% of that 30 years before. Consequently, some initiatives for the replenishment of exhausted wild stocks are welcome. The objective of the present work is to describe and analyse the results coming from the first flatfish stock enhancements in Andalusia. A total of 3189 fish from three flatfish species: Senegal sole (Solea senegalensis Kaup), wedge sole (Dicologlossa cuneata Moreau), and brill (Scophthalmus rhombus Linnaeus) were tagged and released. Several variables were calculated through the data analysis of recovered fish. Some variables were calculated only for Senegal soles since wedge sole and brill recaptures were not significant. The Senegal sole recapture rate was 2.71 ± 0.72, similar to other published data, the recapture rates for bigger fish being higher though not significant. No significant differences were detected for distance, time, growth, or recapture rate amongst initial Senegal sole sizes. Around 80% of recaptures were registered within 15 weeks after release. The results show that it is possible for the release and recovery of tagged Senegal soles in the Gulf of Cadiz. Future long-term programmes on stock enhancement could help to determine the effects on fisheries and recover stocks.
The IFMIF-DONES Project: Design Status and Main Achievements Within the EUROfusion FP8 Work Programme
Authors: Bernardi D. , Ibarra A. , Arbeiter F. , Arranz F. , Cappelli M. , Cara P. , Castellanos J. , Dzitko H. , García A. , Gutiérrez J. , Królas W. , Martin-Fuertes F. , Micciché G. , Muñoz A. , Nitti F. S. , Pinna T. , Podadera I. , Pons J. , Qiu Y. , Román R. 
Published: October 2022

AbstractInternational Fusion Materials Irradiation Facility-DEMO-Oriented NEutron Source (IFMIF-DONES) is a high-intensity neutron irradiation facility for qualification of fusion reactor materials, which is being designed as part of the European roadmap to fusion-generated electricity. Its main purpose is to study the behavior of materials properties under irradiation in a neutron flux able to simulate the same effects in terms of relevant nuclear responses as those expected in the first wall of the DEMO reactor which is envisaged to follow ITER. It is thus a key facility to support the design, licensing and safe operation of DEMO as well as of the fusion power plants that will be developed afterwards. The start of its construction is foreseen in the next few years. In this contribution, an overview of the IFMIF-DONES neutron source is presented together with a snapshot of the current engineering design status and of the relevant key results achieved within the EUROfusion Work Package Early Neutron Source (WPENS) as part of the 2014–2020 EURATOM Research and Training Programme, complementary to the EU Horizon 2020 Framework Programme (FP8). Moreover, some information on the future developments of the project are given.
Nonlinear interaction of parametric excitation and self-excited vibration in a 4 DoF discontinuous system
Authors: Sani Godwin , Balaram Bipin , Awrejcewicz Jan 
Published: October 2022

AbstractInteraction between parametric excitation and self-excited vibration has been subjected to numerous investigations in continuous systems. The ability of parametric excitation to quench self-excited vibrations in such systems has also been well documented. But such effects in discontinuous systems do not seem to have received comparable attention. In this article, we investigate the interaction between parametric excitation and self-excited vibration in a four degree of freedom discontinuous mechanical system. Unlike majority of studies in which oscillatory nature of stiffness accounts for parametric excitation, we consider a much more practical case in which parametric excitation is provided by a massless rotor of rectangular cross section with a cylinder-like mass concentrated at the center. The rotor arrangement is placed on a friction-induced self-excited support in the form of a frame placed on a belt moving with constant velocity. This frame is connected to a supplementary mass. A Stribeck friction model is considered for the mass in contact with the belt. The frictional force between the mass and the belt is oscillatory in nature because of the variation of normal force due to parametric excitation from the rotor. Our investigations reveal mutual synchronization of parametric excitation and self-excited vibration in the system for specific parameter values. The existence of a stable limit cycle with constant synchronized fundamental frequency, for a range of parametric excitation frequencies, is established numerically. Investigation based on frequency spectra and Lissajous curves reveals complex synchronization patterns owing to the presence of higher harmonics. The system is also shown to exhibit Neimark–Sacker bifurcations under the variation of belt velocity. Furthermore, variation in belt velocity and coupling stiffness is seen to cause a breakup of quasi-periodic torus with small-amplitude oscillations to form large amplitude chaotic orbits. This points toward the possibility of vibration suppression in the system by tuning the parameters for stabilizing the small-amplitude quasi-periodic response. An example of co-existence of different attractors in the system is also presented.
Assessing the effectiveness of the TaMATE1B and TaALMT1 genes to enhance the Al3+ tolerance of durum wheat (Triticum turgidum) grown under controlled conditions and in the field
Authors: Kawasaki Akitomo , Wasson Anton P. , Kielnhofer Evangeline , Ryan Peter R. , Delhaize Emmanuel 
Published: October 2022

Abstract
Purpose
Durum wheat is sensitive of acid soils because it lacks effective genes for Al3+ tolerance. Previous research showed introgression of the TaMATE1B and TaALMT1 genes individually increased the Al3+ tolerance of durum wheat. Here we aimed to (a) combine the genes into a single durum line, (b) compare the various introgression lines and (c) establish the effectiveness of the introgressions in improving the acid soil tolerance in the field.

Methods
Durum wheat lines homozygous for Al3+-tolerant alleles of TaMATE1B and TaALMT1 were crossed to develop a line that incorporated both genes. The parental cultivar, lines with the individual genes and the line with both genes introgressed were screened for Al3+ tolerance by hydroponic and soil cultures in a growth cabinet. The lines were also assessed for biomass production and grain yield in the field on acid soils.

Results
The durum wheat lines with the various Al3+-tolerance genes introgressed performed better based on root growth than Jandaroi, the parental cultivar, in both hydroponic and soil assays when grown in a cabinet. The various introgression lines were tolerant of acid soils compared to Jandaroi when grown in the field as assessed by shoot biomass and grain yield.

Conclusion
The TaALMT1 and TaMATE1B genes improve the acid soil tolerance of durum wheat with indications that combining both genes is the most effective strategy. The various lines will be valuable to breeders who wish to enhance the acid soil tolerance of durum germplasm.
Educational needs, motives and experiences of sex care workers for people with disabilities in the Netherlands
Authors: Hilberink S. R. , van der Stege H. A. , Kelders Y. 
Published: October 2022

AbstractIn some countries, personal assistants may facilitate sexual engagement of people with disabilities. A specific form of facilitating sexuality are services that offer paid sex with sex care workers. In the Netherlands, there is no training available for sex care workers. To provide input for such training, this study examined sex care workers’ (perceived importance of) knowledge about sexuality and relevant aspects of sex care, their educational needs, motives for becoming a sex care worker, and experiences. An online survey was completed by 29 sex care workers (response rate 52%). The sex care workers expressed high importance of knowledge and generally reported good, but slightly lower current knowledge levels on these aspects. Educational needs included both general and disability-related sexuality and sexual problems and how to deal with problem behaviors and/or emotional disinhibition. Some participants indicated that learning how to prevent physical strain was important. The importance of setting boundaries was reported. Overall, participants experienced little stigma, although few reported negative experiences. Important motives for sex care work included the lack of attention to sexuality support for clients with disabilities and wanting to contribute to clients’ sexual citizenship. The formulated educational needs may be helpful in the development of such training. In addition to knowledge and practical skills, the training should pay attention to discovering and setting boundaries, providing a safe space for reflection on one’s own body experience and ethics, as well as considering the clients’ perspectives.
Noble Gases and Stable Isotopes Track the Origin and Early Evolution of the Venus Atmosphere
Authors: Avice Guillaume , Parai Rita , Jacobson Seth , Labidi Jabrane , Trainer Melissa G. , Petkov Mihail P. 
Published: October 2022

AbstractThe composition the atmosphere of Venus results from the integration of many processes entering into play over the entire geological history of the planet. Determining the elemental abundances and isotopic ratios of noble gases (He, Ne, Ar, Kr, Xe) and stable isotopes (H, C, N, O, S) in the Venus atmosphere is a high priority scientific target since it could open a window on the origin and early evolution of the entire planet. This chapter provides an overview of the existing dataset on noble gases and stable isotopes in the Venus atmosphere. The current state of knowledge on the origin and early and long-term evolution of the Venus atmosphere deduced from this dataset is summarized. A list of persistent and new unsolved scientific questions stemming from recent studies of planetary atmospheres (Venus, Earth and Mars) are described. Important mission requirements pertaining to the measurement of volatile elements in the atmosphere of Venus as well as potential technical difficulties are outlined.
Pandemics, policy, and pluralism: A Feyerabend-inspired perspective on COVID-19
Authors: Bschir Karim , Lohse Simon 
Published: October 2022

AbstractWe analyse insufficient epistemic pluralism and associated problems in science-based policy advice during the COVID-19 pandemic drawing on specific arguments in Paul Feyerabend’s philosophy. Our goal is twofold: to deepen our understanding of the epistemic shortcomings in science-based policy during the pandemic, and to assess the merits and problems of Feyerabend’s arguments for epistemic pluralism as well as their relevance for policy-making. We discuss opportunities and challenges of integrating a plurality of viewpoints from within and outside science into policy advice thus contributing to discussions about normative issues concerning evidence and expertise in policy-making.
Transport of Organic Volatiles through Paper: Physics-Informed Neural Networks for Solving Inverse and Forward Problems
Authors: Serebrennikova Alexandra , Teubler Raimund , Hoffellner Lisa , Leitner Erich , Hirn Ulrich , Zojer Karin 
Published: October 2022

AbstractTransport of volatile organic compounds (VOCs) through porous media with active surfaces takes place in many important applications, such as in cellulose-based materials for packaging. Generally, it is a complex process that combines diffusion with sorption at any time. To date, the data needed to use and validate the mathematical models proposed in literature to describe the mentioned processes are scarce and have not been systematically compiled. As an extension of the model of Ramarao et al. (Dry Technol 21(10):2007–2056, 2003) for the water vapor transport through paper, we propose to describe the transport of VOCs by a nonlinear Fisher–Kolmogorov–Petrovsky–Piskunov equation coupled to a partial differential equation (PDE) for the sorption process. The proposed PDE system contains specific material parameters such as diffusion coefficients and adsorption rates as multiplication factors. Although these parameters are essential for solving the PDEs at a given time scale, not all of the required parameters can be directly deduced from experiments, particularly diffusion coefficients and sorption constants. Therefore, we propose to use experimental concentration data, obtained for the migration of dimethyl sulfoxide (DMSO) through a stack of paper sheets, to infer the sorption constant. These concentrations are considered as the outcome of a model prediction and are inserted into an inverse boundary problem. We employ Physics-Informed Neural Networks (PINNs) to find the underlying sorption constant of DMSO on paper from this inverse problem. We illustrate how to practically combine PINN-based calculations with experimental data to obtain trustworthy transport-related material parameters. Finally we verify the obtained parameter by solving the forward migration problem via PINNs and finite element methods on the relevant time scale and show the satisfactory correspondence between the simulation and experimental results.