bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Social Media Technology, Packaging and Online Promotion on Increasing Sales of Food Products Group of Mothers in Bojong Kulur Village, Bogor
Authors: Setiawan Elfa , Fantini Endah , Samsudin Samsudin 
Published: June 2022

This study had a goal to detemine the effect of media social technology, packaging, and online promotion on increasing sales of culinary products group of women in Bojong Kulur village, Bogor, West Java. It also aimed to analyze the most dominant factor in increasing the sales. There were 175 respondents who were taken randomly in Bojong Kulur village area during the period of January to May 2021. The technique of Incidental Sampling was used to gather questionnaires from producers and consumers. Descriptive statistical analysis using SPSS version of 22 was used as the method of data analysis in this study.Research result showed that variable of Media Social Technology, Packaging, and Online Promotion, and Packaging influenced the variable Sales Increase. Based on the result, it was found that the calculated F value was 66.567 > F table 3.05 and the sig value. of 0.000 < 0.05. It also concluded that concluded that those three independant variables have a simultaneous effect on increasing sales as the dependant variable.
Strategic Alliance in the Creative Economy:Acquisition Coach's of Kate Spade
Authors: Hesti Wibowo Daryanto 
Published: June 2022

This study is an analytical research on the application of strategic alliances in the creative economy in a global context. Creative economy is not just about small and medium scale industry, but its economic potential is very gigantic. The world trade in creative industry-based goods and services in the Special Edition of the United Nations Creative Economy Report, has recorded a trade of USD 624 billion in 2011. This study analyzes the acquisition of Coach's exclusive handbag company against its competitor, Kate Spade. Using the literature and business information, the analysis shows that the acquisition of May 2017 is a Coach reaction to the tight competition dynamics in the exclusive handbag industry. In order to win the competition, Coach decided to acquire Kate Spade worth USD 2.4 billion or around IDR 31.9 trillion. With this acquisition value, Coach hopes to boost its sales performance through market expansion by leveraging the competitive advantage of its partner Kate Spade. This analysis can be used as a reference for the creative economy development in Indonesia, especially handbag industry which is currently starting to penetrate international markets such as Dowa and Laga.
Komunikasi Interpersonal Antara Koordinator Dan Anggota Pengelola Ruang Publik Terpadu Ramah Anak Kelurahan Galur Jakarta Pusat
Authors: Septian Muhammad , Rosma Angelika 
Published: June 2022

Interpersonal communication between the coordinator and members has an important role in supporting performance, but conditions show that interpersonal communication between the implementers of the Galur Village RPTRA Manager still looks bad, this can be seen from the frequent misunderstandings in the process of carrying out tasks. Thus, the research question can be formulated, namely how is Interpersonal Communication Between Coordinators and Members of the Child Friendly Integrated Public Space Management (RPTRA) Galur Village, Central Jakarta Administration, and the aim is to find out the Interpersonal Communication between the Coordinator and Members of the Child Friendly Integrated Public Space Management (RPTRA) Galur Village, using descriptive qualitative research methods through observation and in-depth interviews with informants, namely the management members as the object of research. The results of the study show: a), there is still weak or lack of communication between the coordinator and the management members so that they become passive in interacting, b) there are obstacles, namely the lack of discussion space and regular meetings. The research suggestions to overcome the obstacles faced are by scheduling regular meetings, making capacity building/training training, increasing the capacity of members, and family gatherings to increase intimacy
Implementasi Strategi Komunikasi Pemasaran Produk Cawang AC Pro PT Gobel Dharma Nusantara di Masa Pandemi Korona
Authors: Kartikawati Dwi 
Published: June 2022

The research focused on the implementation of marketing communication strategy on Cawang Pro Air Conditioning Product at PT Gobel Dharma Nusantara during the corona virus pandemic . Since the corona virus (covid-19) pandemic has spread to almost all corners of the world, has hit the business of goods and services. Many companies must quickly adapt to this condition and also very tight business competition in Air Conditioning products. PT Gobel Dharma Nusantara must adjust to these conditions to anticipate the product disappearing from the market, which is caused by the health crisis. The theoretical framework used in this study is the concept of marketing communication, model concept, marketing communication strategy, online media utilization and AISAS theory. This research was qualitative research with a case study method. The results showed that the implementation of the marketing communication strategy at PT. Gobel Dharma Nusantara have done 3 strategic steps. The first step is planning communication marketing including determining marketing communications objectives, setting a marketing communications budget, and determining the development of marketing communications programs. The second step is executing on marketing communications by changing the tools and elements of marketing communications digitally. The third step is evaluating. Thus, the entire implementation of marketing communications is carried out continuously so that the company continues to exist in the midst of the corona virus pandemic situation
Significance of D-dimer in Assessment of Severity and Mortality of COVID-19 Patients A Tertiary Care Hospital Study
Authors: Suruthy Ashwini , Vishwanathan Neethu Gowdru , Bijjaragi Seema 
Published: June 2022

The outbreak of COVID-19 has brought public health emergency worldwide and has been the biggest challenge to date. This study aims to study the correlation between D-dimer levels with severity and mortality in COVID-19 patients. This study will help us understand the disease's progression and monitor the disease severity and mortality in Covid-19 patients. This retrospective descriptive study was conducted over four months from April 2021- to June 2021 in a tertiary care hospital in Central Karnataka. Demographic details and clinical and laboratory parameters were obtained from electronic hospital records. Inclusion criteria are Patients who were RT-PCR confirmed positive cases were only included in this study. Exclusion criteria are Patients who had cancer, hematologic malignancies, and acute coronary syndrome were all excluded. Results of the research are A total of 75 cases were evaluated and analyzed in this study. Patients were categorized based on severity as mild to moderate and severe. Out of which 50 patients had recovered from the illness, and 25 patients have succumbed to death. Our study revealed that elevated D-dimer levels were significant (p&lt;0.02) with the outcome of the disease, and with the mean level of 929.27 in severe patients and 466.47 in mild-moderate patients, elevated D-dimer were highly significant (p&lt;0.001) with the severity of the disease. Conclusion research detailed investigations of 75 COVID-19 patients suggests that a significant increase in D-dimer levels was associated with mortality and severity of the disease. Therefore, we strongly recommend that the D-dimer be used to screen patients with COVID-19 to evaluate the severity and predict the prognosis and mortality in hospitalized COVID-19 patients during admission and follow-up throughout hospitalization.
Pengaruh Modal Kerja Terhadap Profitabilitas Perusahaan Perdagangan Eceran di Bursa Efek Indonesia
Authors: Sukmadewi Refni 
Published: June 2022

The purpose of this study is to determine the effect of working capital management which consists of: Cash Turnover, Accounts Receivable Turnover and Inventory Turnover on the level of profitability in retail trading companies listed on the Indonesia Stock Exchange in 2017-2019. This research uses quantitative research by observing and studying audited financial reports from retail trading companies listed on the Indonesia Stock Exchange during the study period. The analysis method used is multiple regression analysis. The sample of this study amounted to 14 companies. The results of this study indicate that partially working capital management which consists of: Cash Turnover has a positive effect on Profitability, Receivables Turnover has a positive effect on Profitability and Inventory Turnover has a positive and significant effect on profitability in retail trading companies listed on the Indonesia Stock Exchange 2017-2019. Furthermore, simultaneously working capital management which consists of: Cash Turnover, Accounts Receivable Turnover and Inventory Turnover affect the profitability of 2017-2019 companies listed on the Indonesia Stock Exchange 2017-2019.

Keywords: Cash Turnover, Accounts Receivable Turnover, Inventory Turnover, Working Capital, Profitability
Banks in Midst of Fintech and Neobanks
Authors: Hidayat Adrian 
Published: June 2022

In the year of 2021more and more challenging. The banking industry facing the urgency of the fundamental reinforecement. No one can predict that the affect of COVID-19 pandemic has already 1 year and the waves affected financial and economy in the country.
The banking industry are suffering so much, and the intermediary system is quite slow, especially in the credit granting to banking-customer. The business is practically slowing down and even more, they are on the critical situations, therefore the credit-demand is also slowing down. At the same time, credit quality is becoming worse scenario, due to so many creditor facing bad business situation, and therefore they can not pay the credit installment.
On this 2021 situation, the banking industry can not wait preparing the future financial-technology (Fintech), such as developing the infrastructure as well as the products to gain more customer and giving more benefits on digital payment system.
ОСНОВНІ ЧИННИКИ ФОРМУВАННЯ ВИДОВИХ ВИЩИХ ВІЙСЬКОВИХ НАВЧАЛЬНИХ ЗАКЛАДІВ НА ПРИКЛАДІ ВІЙСЬКОВО-ПОВІТРЯНИХ ТА ВІЙСЬКОВО-МОРСЬКИХ СИЛ ЗБРОЙНИХ СИЛ УКРАЇНИ
Authors: Корольов Станіслав 
Published: June 2022

В даній статі висвітлюються основні заходи, які проводилися під час військового будівництва України в рамках створення системи вищих військових навчальних закладів видів Збройних Сил України для підготовки військових фахівців Військово-Повітряних Сил та Військово-Морських Сил Збройних Сил України. При цьому висвітлюються процеси щодо формування серед вищих військових навчальних закладів України саме таких, які мали готувати спеціалістів відповідного фаху для видів Збройних Сил України згідно їх майбутнього призначення щодо виконання бойових завдань. Також приводяться приклади виконання подібних заходів досвіду країн-членів НАТО, зокрема, США.
Ключові слова: вищі військові навчальні заклади, військові фахівці, види Збройних Сил України, підготовка, заходи, забезпечення, законодавство, формування, будівництво, Військово-Повітряні Сили, Військово-Морські Сили Збройних Сил України.
Investigation of a Novel Interleaved Buck Converter for Renewable Energy Applications: Design and Analysis
Authors: Popuri Madhuchandra , Bhajana Veera Venkata Subrahmanya Kumar , Maharana Manoj Kumar 
Published: June 2022

In this paper, a new interleaved buck converter with soft-switching is investigated. The soft-switching condition, zero voltage zero current switching (ZVZCS) of IGBTs during turn-on is obtained with the help of a soft-switching cell that includes active and passive devices that is incorporated in the interleaved buck converter (IBC). The presence of the soft-switching cell reduces the switching losses and improves the overall efficiency. The IGBTs in the converter achieved ZVZCS turn on operations, while converter is operated under both light and heavy loads. The principles of operation and theoretical aspects of the proposed converter system 400 V / 110 V / 2.5 kW are verified with simulation analysis.
Past and Future Practical Solutions for Torsional Vibration Damping in Vehicle Industry
Authors: Venczel Márk , Veress Árpád , Peredy Zoltán 
Published: June 2022

In addition to material and production costs, consumption and emission limits, the requirements for performance, efficiency and space utilization must be met when it comes to the design of today's internal combustion engines for the automotive industry. As a result, three new design trends have been emerged (based on J. Pfleghaar and B. Lohmann's paper in 2013): 1. downsizing: reduction of engine size (number of pistons and stroke) for fuel and space-saving and CO2 emission reduction purposes, 2. downspeeding: reduction of engine speed to save fuel, which necessarily entails significantly higher torques being generated and transmitted in the engine, 3. turbo supercharging: increasing the pressure and compression ratio in the engine piston cylinder to cover the increased torque demand, which is accompanied by NOx gas emissions. Due to these new design trends, significant transverse, axial, and torsional oscillations can occur on the engine's crankshaft. To avoid power loss and fatigue due to the torsional oscillations, a torsional vibration damper is advised to be installed on the free end of the crankshaft or integrated into the flywheel. This review paper focuses on the possible reasons for torsional vibrations, the applied methods used to dampen them, and expected future trends.
Single Cell Meta-Analysis of Endothelial to Mesenchymal Transition (EndMT) in Glucose Metabolism of the Digestive Diseases
Authors: Zhou Qiao , Zhang Xin , Tong Xia , Tang Chuang , Chen Xin , Peng Ling , Xia Xiangen , Zhang Lanlan 
Published: June 2022

Background: Endothelial-to-mesenchymal transition (EndMT) is poorly understood in digestive diseases, and the function of metabolism in EndMT is uncertain.Objective: The goal of this study is to elucidate the role of EndMT in digestive diseases and to describe its metabolic state.Method: The GEO database was used to extract single-cell data in order to discover EndMT subpopulations in digestive organs such as premalignant lesions and cancer of the stomach, intestine, and pancreas.Results: By single-cell RNA sequencing in digestive diseases, we generated a single-cell atlas from tissues of patients spanning a cascade of premalignant lesions and cancer. We next established a single-cell network elucidating the cellular and molecular characteristics of endothelial cells (ECs) across many lesions and identified key genes linked with EndMT in premalignant lesions and cancer lesions. The EndMT activation of a wide variety of metabolic signaling pathways was discovered in ECs, and further study of premalignant lesions and cancer tissue indicated that glucose metabolism increased in premalignant lesions and reached a maximum in cancer tissue. Finally, it was shown that INSR and LDHA might be used as prognostic markers for developing premalignant lesions to cancer involving glucose metabolism in digestive diseases.Conclusion: For the first time, we discovered EndMT’s role in digestive diseases and described its metabolism, underscoring its crucial role in glucose metabolism in the disease. We found several targets via gene screening that are beneficial for predicting premalignant lesions that progress to cancer.
High Fall Risk Associated With Memory Deficit and Brain Lobes Atrophy Among Elderly With Amnestic Mild Cognitive Impairment and Mild Alzheimer’s Disease
Authors: Huang Shuyun , Zhou Xinhan , Liu Yajing , Luo Jiali , Lv Zeping , Shang Pan , Zhang Weiping , Lin Biqing , Huang Qiulan , Feng YanYun , Wang Wei , Tao Shuai , Wang Yukai , Zhang Chengguo , Chen Lushi , Shi Lin , Luo Yishan , Mok Vincent C. T. , Pan Suyue , Xie Haiqun 
Published: June 2022

ObjectivesThis study aimed to primarily examine the association between memory deficit and increased fall risk, second, explore the underlying neuroanatomical linkage of this association in the elderly with aMCI and mild AD.MethodsIn this cross-sectional study, a total of 103 older adults were included (55 cognitively normal, CN; 48 cognitive impairment, CI, elderly with aMCI, and mild AD). Memory was assessed by the Auditory Verbal Learning Test (AVLT). Fall risk was evaluated by the Timed Up and Go (TUG) Test, heel strike angles, and stride speed, which were collected by an inertial-sensor-based wearable instrument (the JiBuEn™ gait analysis system). Brain volumes were full-automatic segmented and quantified using AccuBrain® v1.2 from three-dimensional T1-weighted (3D T1W) MR images. Multivariable regression analysis was used to examine the extent of the association between memory deficit and fall risk, the association of brain volumes with memory, and fall risk. Age, sex, education, BMI, and HAMD scores were adjusted. Sensitivity analysis was conducted.ResultsCompared to CN, participants with aMCI and mild AD had poorer cognitive performance (p &lt; 0.001), longer TUG time (p = 0.018), and smaller hippocampus and medial temporal volumes (p = 0.037 and 0.029). In the CI group, compared to good short delayed memory (SDM) performance (AVLT &gt; 5), the elderly with bad SDM performance (AVLT ≤ 3) had longer TUG time, smaller heel strike angles, and slower stride speed. Multivariable regression analysis showed that elderly with poor memory had higher fall risk than relative good memory performance among cognitive impairment elderly. The TUG time increased by 2.1 s, 95% CI, 0.54∼3.67; left heel strike angle reduced by 3.22°, 95% CI, −6.05 to −0.39; and stride speed reduced by 0.09 m/s, 95% CI, −0.19 to −0.00 for the poor memory elderly among the CI group, but not found the association in CN group. In addition, serious medial temporal atrophy (MTA), small volumes of the frontal lobe and occipital lobe were associated with long TUG time and small heel strike angles; small volumes of the temporal lobe, frontal lobe, and parietal lobe were associated with slow stride speed.ConclusionOur findings suggested that memory deficit was associated with increased fall risk in the elderly with aMCI and mild AD. The association might be mediated by the atrophy of medial temporal, frontal, and parietal lobes. Additionally, increased fall risk, tested by TUG time, heel stride angles, and stride speed, might be objective and convenient kinematics markers for dynamic monitoring of both memory function and fall risk.
Comparative Efficacy and Safety of Poly (ADP-Ribose) Polymerase Inhibitors in Patients With Ovarian Cancer: A Systematic Review and Network Meta-Analysis
Authors: Luo Jing , Ou Shunlong , Wei Hua , Qin Xiaoli , Jiang Qian 
Published: June 2022

ObjectiveThis study aims to compare the efficacy and safety of different poly (ADP-ribose) polymerase (PARP) inhibitors in patients with ovarian cancer through a network meta-analysis to support clinical treatment choices.MethodsThe Cochrane Library, PubMed, Embase, Science Citation Index, China National Knowledge Infrastructure (CNKI), Wanfang Data, Chongqing VIP (CQVIP), and Chinese BioMedical Literature Database (CBM) were searched with a cutoff date of 14 January 2021. ClinicalTrials.gov was also checked for supplementary data. Phase II or III randomized controlled trials that compared a PARP inhibitor with a placebo in patients with relapsed or newly diagnosed advanced ovarian cancer were included. The hazard ratios (HRs) for progression-free survival and overall survival and odds ratios (ORs) for grade 3 or higher adverse events were analyzed. The network meta-analysis was conducted in a Bayesian framework based on the Markov Chain Monte Carlo model in the R gemtc package (version 4.0.3).ResultsEight eligible articles reporting six trials with a total of 2,801 patients were incorporated in this network meta-analysis. Three trials compared olaparib with placebo. Two trials compared niraparib with placebo. One trial compared rucaparib with placebo. The network meta-analysis failed to show significant differences in progression-free survival among the three PARP inhibitors: HR of 0.64, 95% confidence interval of 0.3 to 1.42 for olaparib versus niraparib, and olaparib versus rucaparib (0.86; 0.33 to 2.33). The comparison between niraparib and rucaparib also did not express a statistical difference (1.34; 0.47 to 3.72). Subgroup analysis bybreast cancer susceptibility gene (BRCA) status showed no obvious difference in progression-free survival among the three PARP inhibitors regardless of BRCA mutation status. Olaparib had fewer grade 3 or higher adverse events than niraparib (OR, 0.27; 95% confidence interval, 0.13 to 0.55) and rucaparib (0.34; 0.14 to 0.86). However, the analysis failed to show a significant difference between niraparib and rucaparib (1.27; 0.49 to 3.27).ConclusionCurrent evidence indicates that there is no significant difference observed in efficacy among olaparib, niraparib, and rucaparib. However, olaparib might have fewer grade 3 or higher adverse events.
Cross-Sectional and Longitudinal Associations Between the Serum G\lobulin Level, and Renal Impairment and All-Cause Deaths in Chinese Patients With Newly Diagnosed Multiple Myeloma
Authors: Cheng Jun , Sun Jia , Zhao Yi , Li Xiayu , Jiang Yan , Lv Rong , Li Heng , Chen Jianghua 
Published: June 2022

BackgroundA large number of studies have shown that serum globulin plays an important role in a variety of cancers; However, few studies have identified the association between serum globulin levels and end-stage renal disease (ESRD) and all-cause death in Chinese patients with multiple myeloma (MM).MethodsA generalized additive model and smooth curve fitting were fitted to assess the cross-sectional relationship between the serum globulin levels and renal impairment (RI) at baseline. Multivariate-adjusted Cox regression models were performed to determine the associations between the baseline serum globulin levels and the onset of all-cause death and ESRD in patients with MM.Results288 participants who were followed for &gt; 3 months were eligible for the retrospective study. The median serum globulin level was 5.1 ± 2.6 mg/dL. The average follow-up time was 23.3 months. Thirty-two patients (11.5%) had ESRD and 24 patients (8.33%) died after diagnosis. In patients with a serum globulin level &lt; 6.1 mg/dL, the serum globulin level had an independent, negative correlation with the occurrence of MM-related RI. Patients were divided into three groups on the basis of serum globulin tertiles: low (L group), 3.3 mg/dL; middle (M group), 3.3–6.0 mg/dL; and high (H group), 6.0 mg/dL. Cox regression analysis showed that low serum globulin levels may be independent risk factors for all-cause death and the occurrence of ESRD in patients with MM; however, an elevated baseline serum globulin can predict all-cause deaths in patients with MM, but cannot predict the onset of ESRD.ConclusionsThis observational study suggested that there was a non-linear relationship between the serum globulin level and the occurrence of RI in patients with MM. This finding showed that the serum globulin level had a U-shaped association with all-cause death and an L-shaped association with ESRD in patients with MM.