bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS DAMPAK SOSIAL-EKONOMI AKIBAT PEMBATASAN SOSIAL BERSKALA BESAR (PSBB) DALAM MENGHADAPI PANDEMI COVID-19 DI PROVINSI DKI JAKARTA
Authors: Rasminto Rasminto , Rasyid Aliy , Adiputra Agung , Amin  , Ain Mihyal 
Published: December 2022

Tujuan penelitian ini adalah untuk mengetahui dampak yang disebabkan oleh pembatasan sosial berskala besar (PSBB) dalam menghadapi pandemik Covid-19 terhadap sosial-ekonomi masyarakat di Provinsi DKI Jakarta dengan meliputi; mengetahui dampak yang terjadi setelah adanya pandemik Covid-19 terhadap pendapatan; dampak pada pekerjaan, upaya bertahan hidup, dan pola usaha. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan pendekatan survei. Hasil penelitian menunjukkan bahwa penerapan PSBB berdampak pada pola pekerjaan, penghasilan masyarakat, permasalahan aktifitas harian dan harmonisasi rumahtangga. Berdasarkan pola pekerjaan berpengaruh dengan adanya pola bekerja di rumah atau work from home (WFH) sebesar 54%, menjadi korban pemutusan hubungan kerja sebesar 18%; penerapan PSBB juga berdampak pada penurunan penghasilan sebesar 76,23% dan hanya 0,49% mengalami peningkatan penghasilan; selain itu juga pada permasalahan aktifitas harian yang paling terdampak adalah sulitnya akses transportasi umum sebesar 35,09% dan dampak pada harmonisasi rumahtangga dengan munculnya persoalan tidak memiliki waktu berkualitas sebesar 57,40%, terjadi cekcok rumah tangga sebesar 10,12% dan terjadi miss-komunikasi sebesar 35,46%.
Pelatihan Keterampilan Pembuatan Batik Versi Milenia Bagi Perempuan
Authors: Nadiroh  , Hasanah Uswatun , Cholilawati  
Published: December 2022

Dalam rangka memperkuat kapasitas laki-laki dan perempuan marjinal korban bencana di sukabumi dalam penguatan home industry batik jumputan dan disain fashion alam versi milenial, butuh kepeduliah dari akademisi untuk bisa berkolaborasi dengan Kelurahan yang terkena dampak bencana atau sekitarnya, dengan perguruan tinggi Islam setempat dan Pengurus PKK di Kabupaten Sukabumi Secara operasional produk dari kegiatan pengabdian kepada masyarakat adalah kain jumputan dengan menggunakan zat warna alam. Adapun materi pelatihan dalam kegiatan pengabdian kepada masyarakat adalah keterampilan pembuatan pola batik jumputan berkarakter alam, di sampuing itu juga penyuluhan tentang pentingnya pelestarian lingkungan dalam pembangunan berkelanjutan: ”Esensi pembangunan berkelanjutan adalah keselarasan hubungan sesama manusia, dengan manusia dan lingkungan. Penyuluhan materi lingkungan dalam pembangunan berkelanjutan disampaikan secara terencana untuk mewujudkan suasana pendampingan kepada 60 orang laki-laki dan perempuan yang rentan akibat korban bencana longsor. Masyarakat telah aktif dapat mengembangkan potensi dirinya untuk memiliki kekuatan spiritual keagamaan, pengendalian diri, kepribadian, kecerdasan, akhlak mulia, serta keterampilan yang diperlukan dirinya, masyarakat, bangsa dan negara. Mendorong perubahan sikap yang membuka jalan bagi keberlanjutan dalam konteks lingkungan, keberlanjutan pembangunan yang adil bagi generasi sekarang maupun yang akan datang. Dalam proses pelaksanaan pelatihan ini telah dilakuka penilaian proses berupa: antusiasme, kerjasama rasa ingin tahu, ikut serta memberikan ide, disiplin, gagasan baru kreatifitas, minat, kemampuan mengemukakan pendapat, dan motivasi. Produk fashion karakter alam versi milenial telah dipromosikan untuk masyarakat sekitar dan masyarakat pengunjung atau wisatawan lokal dan manca negara, berupa kain jumputan yang didisain versi milenial dan tas limbah plastik versi milenial. Pada tahun 2020 di desiminasikan melalui penelitian di NTB.
The THE ROLE OF THE ENVIRONMENT SERVICE IN CREATING A CLEAN CITY IN WAMENA CITY
Authors: HARYATI TATI 
Published: December 2022

Wamena City or Baliem Valley is a unique city located in a mountainous area that is being hunted by foreign tourists. However, the threat of environmental pollution due to waste has become a threat to the innovation policy of the Regional Government of Jayawijaya Regency. Therefore, it is hoped that the Jayawijaya Regency Regional Government will have an active role in this case the Jayawijaya Regency Environmental Service which is of course responsible for the Environmental Cleanliness of Wamena City.
Through a qualitative method, the authors found that the lack of facilities provided by the Jayawijaya Regency Government made it difficult to realize a Clean Wamena City, in addition, which was marked by the behavior of people who were still not aware of the importance of maintaining cleanliness, littering, or the presence of a lot of piles. garbage that can be found everywhere, there is not even a clear sanction for each violator.
Do Prior Information on Performance of Individual Classifiers for Fusion of Probabilistic Classifier Outputs using Yayambo Matter?
Authors: Masakuna Jordan Felicien , Kafunda Pierre Katalay 
Published: December 2022

Abstract
In this paper, a performance-agnostic fusion of probabilistic classifier outputs from [21] (called Yayambo) is modified. Yayambo is iterative and was proposed for combining probabilistic outputs of black-box classifiers trained for the same task to make a single consensus class prediction. Yayambo considers the diversity between the outputs of the various classifiers, iteratively updating predictions based on their correspondence with other predictions until the predictions converge to a consensus decision. [21] treated black-box classifiers. For this paper, cases where prior information, i.e. performances of individual classifiers in
the form of accuracy is taken into account for fusion of classifier outputs are considered. Then we discussed the relevance of prior information for combination of probabilistic classifier outputs. Though informed classifier fusion methods outperform uniformed classifier fusion methods in general, the experiments have demonstrated that performances of classifier fusion methods, for both informed and uniformed fusion methods, depend on nature of data and types of individual classifiers used. This means that one needs to carefully select a classifier fusion method under good understanding of characteristics of data sets and
classification models used. In other words, for some situations, uninformed classifier fusion methods might outperform the informed ones. The modified version of Yayambo (i.e. informed Yayambo) outperforms the uninformed one in most cases considered in this study.
Performance improvement of solar photovoltaic models with parameter extraction by using state-of-art metaheuristic methods
Authors: Bakir Huseyin 
Published: December 2022

Abstract
In today’s technology, solar energy continues to be one of the leading renewable energy sources in electricity production methods due to its abundance on the Earth's surface and non-polluting nature. In solar systems, it is relatively easy to produce the electricity from the sun, and its efficiency can be enhanced with the optimization of the parameters in photovoltaic (PV) systems. From this point of view, the present paper has centered on the parameter optimization of single-diode, double-diode, and three PV module models with state-of-art optimization algorithms. In this direction, flow direction algorithm (FDA), particle swarm optimization (PSO), student psychology-based optimization (SPBO), adaptive guided differential evolution algorithm (AGDE), stochastic fractal search (SFS) and fitness-distance balance based SFS (FDB-SFS) are applied to extract the PV cell parameters. The root-mean-square error (RMSE) is utilized as performance evaluation criteria. For reliable and coherent results, 30 runs of the algorithm are performed. Based on experimental results, the best estimation accuracy is reached by the FDB-SFS algorithm. The mean RMSE values are achieved to be 1.03E-03, 9.90E-04, 2.42E-03, 1.72E-03, and 1.67E-02 for the single-diode, double-diode, Photowatt-PWP201, STM6-40/36, and STP6-120/36 PV modules, respectively. Friedman and Wilcoxon test results verify that FDB-SFS is an efficient and powerful method that can be used for solar PV parameter extraction.
The Role of Multiple Sclerosis Therapies on the Dynamic of Human Gut Microbiota
Authors: Vacaras Vitalie , Muresanu Dafin F , Buzoianu Anca-Dana , Nistor Cristina , Vesa Stefan Cristian , Paraschiv Andreea Cristina , Botos-Vacaras Daniela , Vacaras Cristiana , Vithoulkas George 
Published: December 2022

Abstract
Gut microbiota, the total microorganisms in our gastrointestinal tract, might have an implication in multiple sclerosis (MS), a demyelinating neurological disease. Our study included 50 MS patients and 21 healthy controls (HC). Twenty patients received a disease modifying therapy (DMT), interferon beta1a or teriflunomide, 19 DMT combined with homeopathy and 11 patients accepted only homeopathy. We collected in total 142 gut samples, two for each individual: at the study enrolment and eight weeks after treatment. We compared MS patients’ microbiome with HC, we analysed its evolution in time and the effect of interferon beta1a, teriflunomide and homeopathy. There was no difference in alpha diversity, only two beta diversity results related to homeopathy. Compared to HC, untreated MS patients had a decrease of Actinobacteria, Bifidobacterium, Faecalibacterium prauznitzii and increased Prevotella stercorea, while treated patients presented lowered Ruminococcus and Clostridium. Compared to the initial sample, treated MS patients had a decrease of Lachnospiraceae and Ruminococcus and an increased Enterococcus faecalis. Eubacterium oxidoreducens was reduced after homeopathic treatment. The study revealed that MS patients may present dysbiosis. Treatment with interferon beta1a, teriflunomide or homeopathy implied several taxonomic changes. DMTs and homeopathy might influence the gut microbiota.
Accurate Chemical Abundance of Mrk 71 from Optical and Infrared Spectra
Authors: Chen Yuguang , Jones Tucker , Sanders Ryan , Fadda Dario , Sutter Jessica , Minchin Robert , Huntzinger Erin , Senchyna Peter , Stark Daniel , Spilker Justin , Weiner Benjamin , Roberts-Borsani Guido 
Published: December 2022

Abstract
The heavy element content ("metallicity") of the Universe is a record of the total star formation history. Gas-phase metallicity in galaxies, as well as its evolution with time, is of particular interest as a tracer of accretion and outflow processes. However, metallicities from the widely-used electron temperature (Te) method are typically ~2 times lower than the values based on the recombination line method. This "abundance discrepancy factor" (ADF) is well known and is commonly ascribed to bias due to temperature fluctuations. We present a measurement of oxygen abundance in the nearby (3.4 Mpc) system, Mrk 71, using a combination of optical and far-IR emission lines to measure and correct for temperature fluctuation effects. Our far-IR result is inconsistent (~2.5σ significance) with the metallicity from recombination lines and instead indicates little to no bias in the standard Te method, ruling out the long-standing hypothesis that the ADF is explained by temperature fluctuations for this object. Our results provide a framework to accurately measure metallicity across cosmic history, including with recent data reaching within the first billion years with JWST and the Atacama Large Millimeter Array (ALMA).
Indirect plant-mediated interactions between heterospecific parasitoids that develop in different caterpillar species
Authors: Cuny Maximilien A.C. , Pierron Romain , Gols Rieta , Poelman Erik H. 
Published: December 2022

Abstract
Koinobiont parasitoids induce physiological changes in their herbivorous hosts that affect how plants respond to herbivory. The signature of parasitoids on induced plant responses to feeding by parasitized herbivores indirectly impacts insect communities interacting with the plant. The effect may extend to parasitoids and cause indirect interaction between parasitoids that develop inside different herbivore hosts sharing the food plant. However, this type of indirect plant-mediated interactions (IPMIs) among parasitoid larvae has received very little attention. In this study, we investigated sequential and simultaneous plant-mediated interactions among two host-parasitoid systems feeding on Brassica oleracea plants: Mamestra brassicae parasitized by Microplitis mediator and Pieris rapae parasitized by Cotesia rubecula. We measured the mortality, development time and weight of unparasitized herbivores and performance of parasitoids that had developed inside the two herbivore species when sharing the food plant either simultaneously or sequentially. Plant induction by parasitized or unparasitized hosts had no significant effect on the performance of the two herbivore host species. In contrast, the two parasitoid species had asymmetrical indirect plant-mediated effects on each other’s performance. Cotesia rubecula dry weight was significantly increased by plants induced by M. mediator-parasitized hosts, while M. mediator development time was reduced by plant induced responses to conspecific but not to heterospecific parasitoids. Contrary to sequential feeding, parasitoids had no effect on each others performance when feeding simultaneously. These results reveal that indirect plant-mediated interactions among parasitoid larvae could involve any parasitoid species whose hosts share a food plant.
The effect of photobiomodulation and Akkermansia muciniphila on THP-1 derived macrophage polarization treated with gliadin peptide
Authors: Sherafat Somayeh Jahani- , Rouzbahani Sara Molaaghaee- , Asri Nastaran , Tavirani Mostafa Rezaei , Baghaei Kaveh , Rostami-Nejad Mohammad , Razzaghi Zahra 
Published: December 2022

Abstract

Background and objective: Photobiomodulation (PBM) and Akkermansia muciniphila (A. muciniphila)have been shown to be effective in improving inflammatory conditions with positive effects on increasing the population of anti-inflammatory M2 macrophages. In this study, gliadin stimulated THP-1 derived macrophages were treated with A. muciniphila and PBM to evaluate their effects on promoting the polarization of M2 MQs.
Methods and Results: The human monocyte cell line (THP-1) was differentiated to Macrophages (MQ). MQs were stimulated with 200 μg/ml gliadin for 24 h and then were treated with PBM 810 nm alone and along with Akkermansia muciniphila for following 24 h to evaluate their effects on macrophages polarization. THP-1 derived MQs were also treated with PBM and A. muciniphila to evaluate their effects on non-stimulated MQs. CD11b, CD80, and CD206 levels were evaluated by flow cytometry technique. Moreover, the expression of some M1and M2-related cytokines were determined. PBM of gliadin stimulated MQs decreased IL-6 and increased TGF-β, IL-10 and TNF-α expression compared with gliadin exposed MQs. PBM along with A. muciniphila treatment induced IL-6, TNF-α, and IL-10 expression in MQs in comparison to the untreated group and also elevated TGF-β, IL-10 and TNF-α levels in gliadin triggered MQs related to gliadin stimulated MQ cells.
Conclusion: The result of this study showed the potential of PBMT and A. muciniphila to be used for modulating inflammatory responses and macrophages polarization, which may open new perspectives to find possible therapeutic target for celiac diseases.
Study of the mandibular canal through the diaphanization technique: a possibility for the development of didactic material
Authors: de Lima Natalia Cunha Pinheiro , Macedo Nayara Flores , Vianna Michelle Santos 
Published: December 2022

Abstract
Purpose: The aim of this study is to produce didactic material so that the student of the Dentistry Course can understand the topographic relationship of the mandible canal with the alveolar process and the roots of the permanent teeth in a diaphanized model, right at the beginning of the course.
Material and Methods: The diaphanization technique was applied to a dry human jaw, with all teeth, except the lower first molars, from the Anatomy Laboratory at Pontifícia Universidade Católica do Paraná (PUCPR). Bone decalcification was followed by dehydration, clarification and fixation steps. Subsequently, the bone was analyzed by direct observation of the specimen.
Results: The observation of the mandibular canal was possible only up to the mental foramen region. The ramus suffered much more acid action than the body, given the result of the clarification observed. When comparing the right and left sides, it was observed that on the right side the bone was a little more calcified, revealing less transparency. The characterization of the places where there is compact bone and spongy bone was very evident in the ramus of the mandible.
Conclusions: The technique of diaphanization applied to the human jaw still requires improvement, however, it allowed the production of didactic material that allows the direct visualization of the mandible canal.
ApoE4 causes severe COVID-19 outcomes via downregulation of ACE2
Authors: Chen Feng , Chen Yanting , Ke Qiongwei , Wang Yongxiang , Gong Zheng , Chen Xiongjin , Cai Yujie , Li Shengnan , Sun Yuanhong , Peng Xiaoping , Ji Yao , Zhang Tianzhen , Wu Wenxian , Cui Lili , wang Yan 
Published: December 2022

Abstract
Background
Recent numerous epidemiology and clinical association studies reported that ApoE polymorphism may associate with the risk and severity of coronavirus disease 2019 (COVID-19), and yielded inconsistent results. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection relies on its spike protein binding to angiotensin-converting enzyme 2 (ACE2) receptor expressed on host cell membranes.
Methods
A meta-analysis was conducted to clarify the association between ApoE polymorphism and the risk and severity of COVID-19. Multiple protein interaction assays were utilized to investigate the potential molecular link between ApoE and spike protein and between ApoE and also the SARS-CoV-2 primary receptor ACE2. Immunoblotting and immunofluorescence staining methods were used to access the regulatory effect of different ApoE isoform on ACE2 protein expression.
Results
ApoE gene polymorphism (ε4 carries genotypes VS non-ε4 carries genotypes) is associated with the increased risk (P = 0.0003, OR = 1.44, 95% CI: 1.18–1.76) and progression (P < 0.00001, OR = 1.85, 95% CI: 1.50–2.28) of COVID-19. ApoE interacts with both the spike protein and ACE2 but did not show isoform-dependent binding effects. ApoE4 significantly downregulates ACE2 protein expression in vitro and in vivo and subsequently decreases the conversion of Ang II to Ang 1–7.
Conclusions
ApoE4 increases SARS-CoV-2 infectivity in a manner that may not depend on differential interactions with the spike protein or ACE2. Instead, ApoE4 downregulates ACE2 protein expression and subsequently the dysregulation of renin–angiotensin system (RAS) may provide explanation by which ApoE4 exacerbates COVID-19 disease.
Prediction of recovery after hip arthroplasty in elderly patients with femoral neck fractures based on decision tree model
Authors: Chen Huaping , Xu Xiao , Xia Jingjing , Sun Huiping 
Published: December 2022

Abstract
To investigate the predictive value of the decision tree model for the recovery of femoral neck fractures after hip arthroplasty in elderly patients. A total of 206 elderly patients with femoral neck fractures who received surgeries in our hospital from January 2019 to June 2020 were recruited as subjects. Six months after the operation, they were divided into a good recovery group (Harris score ≥ 70) and a poor recovery group (Harris score < 70) according to the Harris Hip Score. General data, surgical conditions, and postoperative conditions were observed in the two groups. Python language was utilized to construct the decision tree model for postoperative recovery predictions in elderly patients with femoral neck fractures and its performance was verified. After 6 months of follow-up, 3 cases were excluded and 203 cases were finally included. Among them, 158 cases in the good recovery group accounted for 77.83% and 45 cases in the poor recovery group accounted for 22.17%. There were significant differences in age, Charlson comorbidity index, Mini-Mental State Examination score, MNA-SF, FI-CGA score, postoperative weight-bearing time, and social support rating scale score between the two groups (P < 0.05). There was no significant difference in sex and fracture site between the two groups (P > 0.05). Decision tree analysis exhibited that the MNA-SF score was an important factor affecting the postoperative recovery of hip fractures. The best parameters obtained were used for internal verification of the included subjects, and the results demonstrated that the accuracy rate of the model was 88.18%; the sensitivity was 93.33%; the specificity was 86.71%; the positive predictive value was 66.67%; the negative predictive value was 97.86%. The construction of the decision tree model can better exhibit the factors affecting the postoperative recovery of elderly patients with femoral neck fractures, and nutritional status is the most important factor affecting postoperative recovery.
Using genome-wide SSR analysis to understand the genetic diversity and structure of 174 Akebia trifoliata accessions
Authors: Chen Wei , Yang Huai , Yang Hao , Zhong Shengfu , Dong Qing , Chen Chen , Ren Tianheng , Li Zhi , Tan Feiquan , Peigao Luo 
Published: December 2022

Abstract
Genetic diversity is usually regarded as an important role for understanding the origin, evolution and environmental adaptation of species. A total of 174 living collections of Akebia trifoliata and 72 high-polymorphism-potential (HPP) simple sequence repeat (SSR) markers were employed to systematically explore the diversity and structure of this species. The average number of alleles (Na), Shannon's information index (I), number of effective alleles (Ne), observed heterozygosity (Ho), expected heterozygosity (He) and polymorphism information content (PIC) values were 9.01, 1.64, 4.98, 0.56, 0.72 and 0.69, respectively, and the linkage disequilibrium (LD) locus pairs percentage was on 1.17%. The PIC value of AK78 was the highest (0.92), while that of AK53 was the lowest (0.21). Sixty of 72 loci exhibited high polymorphism, while only one exhibited low polymorphism. In addition, the average PIC of chromosomes varied from 0.56 to 0.79. The genetic diversity of the SCB population was the highest, while that of NQH was the lowest. Further analysis of SCB suggested that JSJ-MJ, in the main part of the Heng Duan Mountain zone, had the highest genetic diversity and could be the origin centre of A. trifoliata. The main migration route of A. trifoliata could have been latitudinally from western to eastern China along the Yangtze River. Structure, cluster and principal coordinate analyses yielded similar results, revealing that the 6 populations could be divided into 2 groups or clusters. The geographic origin of several unknown accessions, such as Alc-166, Alc-171, Alc-172 and Alc-174, was revealed by cluster analysis. Overall, the results suggested that the living collections of A. trifoliata had high genetic diversity, good representativeness, and low duplication, which will benefit A. trifoliata germplasm collection, preservation, and breeding applications.