bluuebunny/crossref_metadata_2025_split huggingface dataset:
Making it abstract, making it contestable: politicization at the intersection of political and cognitive science
Authors: Mazzuca Claudia , Santarelli Matteo 
Published: May 2022

AbstractThe notion of politicization has been often assimilated to that of partisanship, especially in political and social sciences. However, these accounts underestimate more fine-grained, and yet pivotal, aspects at stake in processes of politicization. In addition, they overlook cognitive mechanisms underlying politicizing practices. Here, we propose an integrated approach to politicization relying on recent insights from both social and political sciences, as well as cognitive science. We outline two key facets of politicization, that we call partial indetermination and contestability, and we show how these can be accounted for by appealing to recent literature in cognitive science concerned with abstract conceptual knowledge. We suggest that politicizing a concept often implies making its more abstract components more salient, hence legitimating its contestable character. Finally, we provide preliminary suggestions to test our proposal, using the concept of gender as case study.
A review on enhanced biofuel production from coffee by-products using different enhancement techniques
Authors: Sugebo Berhanu 
Published: May 2022

AbstractCoffee by-products are a renewable, plentiful, cost-effective, and mostly untapped resource that could be used as a biofuel feedstock. However, the energy efficiency and biofuel yields are mostly determined by the biofuel production technologies. Pretreatment procedure, hydrolysis methods, fermentation methods, oil to biodiesel conversion techniques, binders employed, applying pressure and temperature are the main factors to improve the biofuel yields from coffee by-products. This paper examines state-of-the-art methods for increasing biogas, bio-ethanol, biodiesel, briquettes, and pellets outputs from coffee by-products. Pretreatment and co-digestion of coffee by-products with other low carbon to nitrogen ratio animal manure boost the biogas yield of coffee by-products, which is also discussed. A yield of bio-ethanol from coffee by-products was also improved using advanced pretreatment procedures, production processes, and the use of genetically modified yeast strains that ferment the majority of sugar monomers. Additionally, oil extraction methods from spent coffee grounds were reviewed, as well as optimizing biodiesel yield from spent coffe grounds oil. The process of making briquettes and pellets, as well as the types of binders utilized, are discussed. The main novelty of this review is on improving biofuel yields such as biogas, bio-ethanol, biodiesel, briquettes, and pellets from the entire dry cherry coffee beans processing residues, wet coffee (coffee pulp or peeled) beans processing residues, and optimizing oil and biodiesel yield from spent coffee grounds.
Contrast-enhanced ultrasound (CEUS) in patients with metastasis-like hepatic alveolar echinococcosis: a cohort study
Authors: Schweizer Melissa , Schmidberger Julian , Schlingeloff Patrycja , Kratzer Wolfgang 
Published: May 2022

Abstract
Purpose
Hepatic alveolar echinococcosis (HAE) of the metastasis-like pattern, according to the Echinococcus Ulm classification, is usually discovered as an incidental finding, and the diagnostic differentiation from “true metastases” is difficult. The aim of this study was to investigate whether lesions of the “metastasis-like pattern” in HAE show a typical contrast behavior that can be used for differentiation from metastasis in malignancies.

Methods
This prospective clinical study included 11 patients with histologically confirmed HAE of the metastasis-like pattern (7 female and 4 male; mean age, 57.1 years; mean disease duration, 59.5 months), who had been examined by B-scan sonography and CEUS, from the National Echinococcosis Registry Germany.

Results
On contrast-enhanced sonography, 11/11 reference lesions showed annular rim enhancement in the arterial and portal venous phases. Throughout the entire 4-min study period, none of the reference lesions showed central contrast enhancement—i.e., all exhibited a complete “black hole sign”. A small central scar was seen in 81.8% of cases.

Conclusion
In clinically unremarkable patients with incidentally detected metastasis-like lesions of the liver, contrast-enhanced sonographic detection of rim enhancement without central contrast uptake (black hole sign) should be considered evidence supporting a diagnosis of hepatic alveolar echinococcosis with a rare metastasis-like pattern. This can help to differentiate HAE from metastases, especially in high-endemic areas.
An overview of functional biolubricants
Authors: Yang Lumin , Zhao Xiaoduo , Ma Zhengfeng , Ma Shuanhong , Zhou Feng 
Published: May 2022

AbstractAt present, more and more diseases are associated with the lubrication dysfunction, which requires a systematic study of the complex lubrication behavior of tissues and organs in human body. Natural biomacromolecular lubricants are essential for maintaining ultra-low coefficients of friction between sliding biological interfaces. However, when the surface lubrication performance of tissues or organs destroys heavily, it will bring friction/shear damage for sliding contact interfaces. Therefore, the application of exogenous biological lubricating materials to improve the lubrication situation of damaged tissue or organ interfaces has attracted extensive attention of researchers. In this review, based on a simple summary of lubrication mechanism at sliding biological interface, we systematically introduce the research progress of several kinds of representatively biolubrication materials, including eye drops, tissue anti-adhesion agents, joint lubricants, and medical device lubricants. Meanwhile, the lubrication mechanism and individual advantage and shortcoming for each of these synthetic exogenous lubricated materials are clarified. Correspondingly, the important lubrication application functionality of these biolubricant materials in typically medical surgery scenes, such as dry eye syndrome, tissue adhesion, arthritis, and interventional medical devices, is discussed. Finally, we look forward to the future development direction of artificial biolubricant materials.
Critical review and functional safety of a battery management system for large-scale lithium-ion battery pack technologies
Authors: See K. W. , Wang Guofa , Zhang Yong , Wang Yunpeng , Meng Lingyu , Gu Xinyu , Zhang Neng , Lim K. C. , Zhao L. , Xie Bin 
Published: May 2022

AbstractThe battery management system (BMS) is the main safeguard of a battery system for electric propulsion and machine electrification. It is tasked to ensure reliable and safe operation of battery cells connected to provide high currents at high voltage levels. In addition to effectively monitoring all the electrical parameters of a battery pack system, such as the voltage, current, and temperature, the BMS is also used to improve the battery performance with proper safety measures within the system. With growing acceptance of lithium-ion batteries, major industry sectors such as the automotive, renewable energy, manufacturing, construction, and even some in the mining industry have brought forward the mass transition from fossil fuel dependency to electric powered machinery and redefined the world of energy storage. Hence, the functional safety considerations, which are those relating to automatic protection, in battery management for battery pack technologies are particularly important to ensure that the overall electrical system, regardless of whether it is for electric transportation or stationary energy storage, is in accordance with high standards of safety, reliability, and quality. If the system or product fails to meet functional and other safety requirements on account of faulty design or a sequence of failure events, then the environment, people, and property could be endangered. This paper analyzed the details of BMS for electric transportation and large-scale energy storage systems, particularly in areas concerned with hazardous environment. The analysis covers the aspect of functional safety that applies to BMS and is in accordance with the relevant industrial standards. A comprehensive evaluation of the components, architecture, risk reduction techniques, and failure mode analysis applicable to BMS operation was also presented. The article further provided recommendations on safety design and performance optimization in relation to the overall BMS integration.
Are Bankers “Crying Wolf”? Type I, Type II Errors and Deterrence in Anti-Money Laundering: The Italian Case
Authors: dalla Pellegrina Lucia , Di Maio Giorgio , Masciandaro Donato , Saraceno Margherita 
Published: May 2022

AbstractExcessive and useless reporting, called the “crying wolf effect,” is a crucial shortcoming that any anti-money laundering (AML) design aims to address. For this reason, in recent years, AML policies in both the US and Europe have switched from a rule-based to a risk-based approach. This study theoretically and empirically investigates whether the risk-based approach delivers the expected results. The theoretical model shows that a trade-off can emerge between accuracy (fewer type-I and type-II errors) and deterrence. The empirical analysis, conducted after the risk-based approach was introduced in Italy, confirms this trade-off. More specifically, deterrence seems a priority, whereas accuracy is sacrificed. In this respect, the data suggest that Italian bankers are likely to “cry wolf.”
Like Visiting an Old Friend: Fischer Glycosylation in the Twenty-First Century: Modern Methods and Techniques
Authors: Haese Matteo , Winterhalter Kai , Jung Jessica , Schmidt Magnus S. 
Published: May 2022

AbstractFischer glycosylation is typically the chemical reaction of a monosaccharide and an alcohol in presence of an acidic catalyst to afford glycosides in pyranosidic and furanosidic forms. This reaction is still applied today for the synthesis of specialized glycosides, and optimization and modification of the method have continued since its discovery by Emil Fischer in the 1890s. This review presents advancements in Fischer glycosylation described in literature of the past 15 years and its implementation in modern chemical methods.
Environmental performance of insect protein: a case of LCA results for fish feed produced in Norway
Authors: Modahl Ingunn Saur , Brekke Andreas 
Published: May 2022

AbstractIn this article, life cycle assessments for six insect protein production cases are examined, and their life cycle inventories are systematically combined to create consistent data and results for the environmental performance of insect protein. The LCAs are on mealworms farmed in the Netherlands or France, fed on cereals or vegetable waste food and brewery side stream (four cases); and black soldier fly larvae farmed in Germany, fed on brewery side stream or brewery side stream with vegetable waste (two cases). The focus is on those insect proteins which can be utilised as fish feed with use in Norway as an example. Special attention is paid to obtain consistent system boundaries, method choices, background data, and indicators. The results show that the insect diet is crucial for all the analysed environmental indicators for insects fed a diet of high economic value vegetables. Emissions from the utilisation of insect manure for biogas, fertilisers or similar, and direct insect greenhouse gas emissions, seem to have little importance. The article further shows results compared with the greenhouse gas emissions for the most important salmon protein feed ingredients in Norway. Insect protein based on vegetables with low economic value has the potential to compete in environmental performance with existing protein sources for fish feed and can also cover 10 to 15% of the volumes of crude protein currently imported to the EU.
Design and Development of a Cold-Flow Test-Bench for Study of Advanced Nozzles in Subsonic Counter-Flows
Authors: Scarlatella Giuseppe , Sieder-Katzmann Jan , Roßberg Florian , Weber Felix , Mancera Carlos T. , Bianchi Daniele , Tajmar Martin , Bach Christian 
Published: May 2022

AbstractAs advanced nozzles may offer alternative solutions to conventional nozzles for the future class of reusable launch vehicles, a critical aspect is to tailor these novel technologies to current recovery strategies, more specifically to vertical landing sustained by retro-propulsion. Researchers at Technische Universität Dresden have developed a dedicated test-bench for the vacuum wind tunnel facility, where Advanced Nozzle Concepts (ANCs), such as aerospike and dual-bell nozzles, are tested in cold-gas configuration while invested by subsonic counter-flows. The main objective of the test campaign is to evaluate the performance and altitude–compensation characteristics of such ANCs by simulating a vertical landing manoeuvre through the variation of ambient pressure experienced during the landing burn. A detailed description of design and development of the test-bench, together with preliminary results from the commissioning activities, are here offered to the reader. The force measurements, together with pressure and temperature data, contribute to evaluate thrust levels and coefficients, as well as the monitoring of the interaction between the nozzle cold-flow and the opposing free-stream. A background-oriented schlieren system allows to visualise the external flow-field. In conclusion, an outline of the upcoming test campaign and a description of the expected results is offered.
Analysis of Space Launch Vehicle Failures and Post-Mission Disposal Statistics
Authors: Fernández Lucía Ayala , Wiedemann Carsten , Braun Vitali 
Published: May 2022

AbstractIn a time in which a significant number of launch vehicles are being developed, boosted by numerous new space actors demanding cheaper access to space, the need to ensure the reliability of launch vehicles and the performance of a successful Post-Mission Disposal (PMD) is undeniable. The first step to ensure the reliability of new launch vehicles is to analyse previous launch failures, learning from past mistakes. In this paper, the launch failures that occurred over the past 16 years are analysed. These failures are classified as a function of the subsystems involved in the failure, as well as the phase of the mission in which the failure occurred. As a result, the most critical subsystems are identified for every mission phase. Subsequently, the most critical subsystem is further investigated, and its most critical components are identified. Furthermore, aiming to improve the present PMD practices, an understanding of the current status is necessary. This paper provides an overview of the evolution in terms of mean orbital lifetime of the rocket bodies launched since the year 2000. Moreover, the number of manoeuvres performed and the orbital lifetime saved by these manoeuvres is analysed between 2016 and 2020, further classifying the statistics by launcher family and country.
A closure result for differential forms in the context of superdensity, approximation of measurable functions by density-degree functions
Authors: Delladio Silvano 
Published: May 2022

AbstractSome properties ofm-density points and density-degree functions are studied. Moreover, the following main results are provided:Let$$\lambda$$λbe a continuous differential form of degreehin$${\mathbb {R}}^n$$Rn(with$$h\ge 0$$h≥0) having the following property: there exists a continuous differential form$$\Delta$$Δof degree$$h+1$$h+1in$${\mathbb {R}}^n$$Rnsuch that$$\begin{aligned} \int _{{\mathbb {R}}^n}\Delta \wedge \omega =\int _{{\mathbb {R}}^n}\lambda \wedge \mathrm{{d}}\omega , \end{aligned}$$∫RnΔ∧ω=∫Rnλ∧dω,for every$$C^\infty _c$$Cc∞differential form$$\omega$$ωof degree$$n-h-1$$n-h-1in$${\mathbb {R}}^n$$Rn. Moreover let$$\mu$$μbe a$$C^1$$C1differential form of degree$$h+1$$h+1in$${\mathbb {R}}^n$$Rnand set$$E:=\{y\in {\mathbb {R}}^n\,\vert \, \Delta (y)=\mu (y)\}$$E:={y∈Rn|Δ(y)=μ(y)}. Then$$\mathrm{{d}}\mu (x) = 0$$dμ(x)=0wheneverxis a$$(n+1)$$(n+1)-density point ofE.Let$$f:{\mathbb {R}}^n\rightarrow {\overline{{\mathbb {R}}}}$$f:Rn→R¯be a measurable function such that$$f(x)\in \{0\}\cup [n,+\infty ]$$f(x)∈{0}∪[n,+∞]for a.e.$$x\in {\mathbb {R}}^n$$x∈Rn. Then there exists a countable family$$\{F_k\}_{k=1}^\infty$${Fk}k=1∞of closed subsets of$${\mathbb {R}}^n$$Rnsuch that the corresponding sequence of density-degree functions$$\{d_{F_k}\}_{k=1}^\infty$${dFk}k=1∞converges almost everywhere tof.
Snow Albedo Feedbacks Enhance Snow Impurity‐Induced Radiative Forcing in the Sierra Nevada
Authors: Huang Huilin , Qian Yun , He Cenlin , Bair Edward H. , Rittger Karl 
Published: May 2022

AbstractThis study employs a fully coupled meteorology‐chemistry‐snow model to investigate the impacts of light‐absorbing particles (LAPs) on snow darkening in the Sierra Nevada. After comprehensive evaluation with spatially and temporally complete satellite retrievals, the model shows that LAPs in snow reduce snow albedo by 0.013 (0–0.045) in the Sierra Nevada during the ablation season (April‐July), producing a midday mean radiative forcing of 4.5 W m−2 which increases to 15–22 W m−2 in July. LAPs in snow accelerate snow aging processes and reduce snow cover fraction, which doubles the albedo change and radiative forcing caused by LAPs. The impurity‐induced snow darkening effects decrease snow water equivalent and snow depth by 20 and 70 mm in June in the Sierra Nevada bighorn sheep habitat. The earlier snowmelt reduces root‐zone soil water content by 20%, deteriorating the forage productivity and playing a negative role in the survival of bighorn sheep.
Hot Plasma Effects on Electron Resonant Scattering by Electromagnetic Ion Cyclotron Waves
Authors: Bashir M. Fraz , Artemyev Anton , Zhang Xiao‐Jia , Angelopoulos Vassilis 
Published: May 2022

AbstractResonant scattering by electromagnetic ion cyclotron (EMIC) waves is one of the most effective mechanisms of relativistic electron losses in Earth’s inner magnetosphere. Low‐altitude spacecraft measurements, however, often show that the energy range of precipitating electrons is wider than theoretical predictions based on the cold plasma dispersion of EMIC waves. To explain this discrepancy, we examine the diffusion rates of EMIC waves by including hot plasma effects in their dispersion relation. Using the observed ion distribution functions, we investigate the hot plasma effects on the EMIC wave dispersion for a wide frequency range. We develop analytical equations for hot plasma effects on EMIC dispersion, and apply this model to diffusion rate evaluations. We show that hot ion effects tend to increase the minimum resonant energy for the frequency range around wave intensity maxima, but can decrease the minimum resonant energy for the higher‐frequency part of wave spectra.
Inability to phosphorylate Y88 of p27Kip1 enforces reduced p27 protein levels and accelerates leukemia progression
Authors: Jäkel Heidelinde , Taschler Martin , Jung Karin , Weinl Christina , Pegka Fragka , Kullmann Michael Keith , Podmirseg Silvio Roland , Dutta Sayantanee , Moser Markus , Hengst Ludger 
Published: May 2022

AbstractThe cyclin-dependent kinase (CDK) inhibitor p27Kip1 regulates cell proliferation. Phosphorylation of tyrosine residue 88 (Y88) converts the inhibitor into an assembly factor and activator of CDKs, since Y88-phosphorylation restores activity to cyclin E,A/CDK2 and enables assembly of active cyclin D/CDK4,6. To investigate the physiological significance of p27 tyrosine phosphorylation, we have generated a knock-in mouse model where Y88 was replaced by phenylalanine (p27-Y88F). Young p27-Y88F mice developed a moderately reduced body weight, indicative for robust CDK inhibition by p27-Y88F. When transformed with v-ABL or BCR::ABL1p190, primary p27-Y88F cells are refractory to initial transformation as evidenced by a diminished outgrowth of progenitor B-cell colonies. This indicates that p27-Y88 phosphorylation contributes to v-ABL and BCR::ABL1p190 induced transformation. Surprisingly, p27-Y88F mice succumbed to premature v-ABL induced leukemia/lymphoma compared to p27 wild type animals. This was accompanied by a robust reduction of p27-Y88F levels in v-ABL transformed cells. Reduced p27-Y88F levels seem to be required for efficient cell proliferation and may subsequently support accelerated leukemia progression. The potent downregulation p27-Y88F levels in all leukemia-derived cells could uncover a novel mechanism in human oncogenesis, where reduced p27 levels are frequently observed.
Noncoding RNA actions through IGFs and IGF binding proteins in cancer
Authors: Kerr Aidan , Baxter Robert C. 
Published: May 2022

AbstractThe insulin-like growth factors (IGFs) and their regulatory proteins—IGF receptors and binding proteins—are strongly implicated in cancer progression and modulate cell survival and proliferation, migration, angiogenesis and metastasis. By regulating the bioavailability of the type-1 IGF receptor (IGF1R) ligands, IGF-1 and IGF-2, the IGF binding proteins (IGFBP-1 to -6) play essential roles in cancer progression. IGFBPs also influence cell communications through pathways that are independent of IGF1R activation. Noncoding RNAs (ncRNAs), which encompass a variety of RNA types including microRNAs (miRNAs) and long-noncoding RNAs (lncRNAs), have roles in multiple oncogenic pathways, but their many points of intersection with IGF axis functions remain to be fully explored. This review examines the functional interactions of miRNAs and lncRNAs with IGFs and their binding proteins in cancer, and reveals how the IGF axis may mediate ncRNA actions that promote or suppress cancer. A better understanding of the links between ncRNA and IGF pathways may suggest new avenues for prognosis and therapeutic intervention in cancer. Further, by exploring examples of intersecting ncRNA-IGF pathways in non-cancer conditions, it is proposed that new opportunities for future discovery in cancer control may be generated.
The contribution of imprinted genes to neurodevelopmental and neuropsychiatric disorders
Authors: Isles Anthony R. 
Published: May 2022

AbstractImprinted genes are a subset of mammalian genes that are subject to germline parent-specific epigenetic modifications leading monoallelic expression. Imprinted gene expression is particularly prevalent in the brain and it is unsurprising that mutations affecting their expression can lead to neurodevelopmental and/or neuropsychiatric disorders in humans. Here I review the evidence for this, detailing key neurodevelopmental disorders linked to imprinted gene clusters on human chromosomes 15q11-q13 and 14q32, highlighting genes and possible regulatory links between these different syndromes. Similarly, rare copy number variant mutations at imprinted clusters also provide strong links between abnormal imprinted gene expression and the predisposition to severe psychiatric illness. In addition to direct links between brain-expressed imprinted genes and neurodevelopmental and/or neuropsychiatric disorders, I outline how imprinted genes that are expressed in another tissue hotspot, the placenta, contribute indirectly to abnormal brain and behaviour. Specifically, altered nutrient provisioning or endocrine signalling by the placenta caused by abnormal expression of imprinted genes may lead to increased prevalence of neurodevelopmental and/or neuropsychiatric problems in both the offspring and the mother.