bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of COVID-19 on child neurodevelopment – An integrative review
Authors: Castro Lucas Teixeira de , Teixeira Leticia Fernandes , Araújo Giselda Tavares de , Guimarães Elaine Leonezi 
Published: April 2022

The effects of COVID-19 on children are still poorly understood. Considering the progressive increase in pediatric cases, we sought to gather evidence of the disease in children, to better understand its evolution, possible complications, and favor clinical practice. This is a review, whose search was carried out in the National Library of Medicine, Latin American & Caribbean Health Sciences Literature (LILACS), Medical Literature Analysis and Retrieval System Online, Virtual Health Library (BVS), PAHO and Cochrane Library. Eight articles were included, and the most common symptoms described were: cold-like symptoms, dry cough, respiratory difficulty, mild throat infection, loss of muscle strength, tonic and reflex changes in the lower limbs. However, there is still no clarity about the disease in children, requiring further research.
A Body Shape Index and Pulse Wave Velocity: strong markers of coronary artery calcification in dyslipidemic patients
Authors: Nagano Francisca Eugenia Zaina , Almeida Cassia Cristina Paes de , Magalhães Tiago Augusto , Cerci Rodrigo Julio , Silva Miguel Morita Fernandes da , Lima Junior Emilton 
Published: April 2022

Objective: To identify, among different Cardiovascular Risk Predictors (CVRP), which have the best associations with Coronary Artery Calcification (CAC). Methodology: Cross-sectional study, with dyslipidemic (age >18), to investigate the association between CVRP [anthropometrics, biochemicals, clinicals, Ankle-Brachial Index (ABI), arterial stiffness] and Coronary Calcium Score (CCS), which was classified according to (1) CCS=0, CCS=1-100, CCS>100, (2) CCS=0, CCS=1-99, CCS=100-299, CCS>300 and (3) dichotomous (CCS=0 or CCS>P75/CCS>100). Bivariate descriptive and inferential statistics were performed. ROC curves estimated the CAC risk of the independent variable. The univariate logistic regression model identified the probability of CAC and established the sensitivity and the specificity of each predictor and the multivariate identified higher risk variables and their respective Odds Ratio (OR). Results: 180 patients evaluated, 65.5% were women, mean age 59.8. CAC was associated with Waist Circumference (p=0.03), A Body Shape Index Risk-ABSIR (p<0.001), Conicity Index (p<0.001), Waist-to-Height Ratio (p<0.001) (T Student test); Pulse Wave Velocity-PWV was associated with CAC for both (1) and (2) CCS classification (p<0.001) (Anova test with Duncan post-hoc test) and it also showed greater sensitivity on ROC curve (3) (AUC 0.61, with a sensitivity of 72.2). In multi-adjusted regression, ABSIR increased the risk of CAC by 3.5 times (CI 95%=1.38-1.64, p=0.001) and PWV by 36% (CI 95%=1.13-1.64, p<0.01). Conclusions: ABSIR and arterial stiffness (PWV) made it possible to obtain a better value for CAC prognosis, being the ABSIR an easy and cheap method, very useful in Public Health.
PENGARUH KUALITAS LAYANAN PEGAWAI TERHADAP KEPUASAN MASYARAKAT (Studi Pada Pengguna Jasa Kepabeanan dan Cukai, Kantor Bea Dan Cukai Kendari)
Authors: Awaludin Trisman , Banga Wempy , Basri Muhammad 
Published: April 2022

Tujuan penelitian ini adalah untuk menganalisis pengaruh kualitas layanan pegawai terhadap kepuasan masyarakat pengguna jasa kepabeanan dan cukai pada Kantor Bea dan Cukai Kendari. Populasi penelitian adalah seluruh pengguna jasa layanan kepabeanan dan cukai yang berurusan dengan Kantor Bea dan Cukai Kendari tahun tahun 2018, sebanyak 106 orang, dan ditetapkan responden sebanyak 53 orang menggunakan pendekatan rumus Slovin dengan presisi 0,1. Data dianalisis menggunakan program SPSSversi 23.0. Hasil penelitian disimpulkan bahwa kualitas layanan pegawai berpengaruh posisitif dan signifikan terhadap kepuasan pengguna jasa kepabeanan dan cukai atas pelayanan. Semakin baik kualitas layanan pegawai maka semakin tinggi pula kepuasan pengguna jasa layanan kepabeanan dan cukai pada kantor Bea dan Cukai Kota Kendari. Kata kunci: kualitas layanan, kepuasan masyarakat
ANALISIS IMPLEMENTASI KEBIJAKAN KOTA LAYAK ANAK DI KOTA KENDARI
Authors: Harianti Puput , Barlian Barlian , Suaib Eka 
Published: April 2022

Penelitian bertujuan untuk mengetahui dan menganalisis implementasi kebijakan kota layak anak di Kota Kendari. Jenis penelitian menggunakan pendekatan kualitatif, penentuan informan menggunakan teknik purposive sampling dengan informan sebanyak 10 orang. Pengumpulan data dalam penelitian ini melalui wawancara, observasi dan studi pustaka. Analisis data meliputi reduksi data, penyajian (display) data, dan menafsirkan data, menyimpulkan data dan verifikasi. Hasil penelitian menunjukan bahwa implementasi kebijakan program kota layak anak sudah berjalan dengan baik namun belum optimal karena dari lima indikator yang digunakan baru dua indikator yang berjalan dengan baik yang meliputi: 1) hak sipil dan kebebasan dan 2) lingkungan keluarga dan pengasuhan alternatif. Sementara itu, tiga indikator lainnya sudah berjalan dengan baik namun belum optimal yang meliputi: 1) kesehatan dasar dan kesejahteraan; 2) pendidikan, pemanfaatan waktu luang, dan kegiatan budaya; dan 3) perlindungan khusus.Kata Kunci : Analisis, Implementasi, Kebijakan Kota Layak Anak
IMPLEMENTASI KEBIJAKAN BADAN USAHA MILIK DESA (BUMDES) DI KECAMATAN PONDIDAHA KABUPATEN KONAWE
Authors: Wati Ritna , Utha Arifin , Mustafa La Ode 
Published: April 2022

Tujuan Penelitian ini adalah untuk mengetahui dan menganalisis implementasi kebijakan Badan Usaha Milik Desa di Kecamatan Pondidaha Kabupaten Konawe. Penelitian ini merupakan jenis penelitian kualitatif yang dianalisis secara kualitatif pula, pengumpulan data dilakuakn dengan wawancara mendalam dengan informan berjumlah sebanyak 15 orang yang ditentukan secara purposive sampling, kemudian data didukung oleh observasi dan dokumentasi. Hasil penelitian ini menunjukkan bahwa implementasi kebijakan BUMDes di Kecamatan Pondidaha Kabupaten Konawe sudah memberikan pelayanan kebutuhan untuk usaha produktif kepada masyarakat yaitu dalam program BUMDes yaitu usaha simpan pinjam. Selanjutnya Implementasi BUMDes di Kecamatan Pondidaha sudah menciptakan pemerataan kesempatan berusaha, kekurangan dari Implementasi BUMDes di Kecamatan Pondidaha adalah sebagian usaha dari BUMDes hanya sebagai penyedia kebutuhan masyarakat bukan usaha untuk meningkatkan pendapatan masyarakat. Kata Kunci: Implementasi Kebijakan, Badan Usaha Milik Desa, kesejahteraan masyarakat
KAJIAN KOMUNIKASI POLITIK ANGGOTA DPRD MUNA BARAT DALAM MEREALISASIKAN JANJI KAMPANYE PADA PILCALEG 2014
Authors: Safrun R Safrun R , Abdullah Muh. Zein , Husain Muh. Najib 
Published: April 2022

Tujuan penelitian ini adalah untuk mengetahui komunikasi politik anggota DPRD Muna Barat dalam meralisasikan janji kampanye pada pilcaleg 2014. Penelitian ini mnggunakan pendekatan kualitatif ditelaah dengan menggunakan deskriptif analisis kualitatif. Hasil penelitian menunjukan bahwa Komunikasi politik Anggota DPRD Muna Barat dalam merealisasikan janji kampanye pada pilcaleg yaitu dengan menyalurkan keanekaragaman pendapat dan aspirasi terhadap masyarakt dan diatur sedemikian rupa agar masyarakt tertarik dengan harapan apa yang menjadi aspirasi masyarakat terakomodir. Dalam proses transaksi komunikasi calon Anggota DPRD kabupaten Muna Barat kepada masyarakat menghasilkan tiga transaksi yaitu, transaksi komplomenter, transaksi silang dan transaksi tersembunyi. DPRD Kabupaten Muna Barat dalam merealisasikan janji kampanya pada pilcaleg tahun 2014. Kata kunci : komunikasi politik, anggota DPRD, janji kampanye
ANALISIS PENGEMBANGAN SUMBER DAYA MANUSIA PEGAWAI DINAS KESEHATAN KABUPATEN KOLAKA
Authors: Sultan Syahrul , Kadir Abdul , Jopang Jopang 
Published: April 2022

Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis pengembangan sumber daya manusia pegawai Dinas Kesehatan Kabupaten Kolaka.Penelitian ini menggunakan pendekatan kualitatif. Informan penelitian ditentukan secara purposive sampling sebanyak 11 orang, terdiri dari Kepala Dinas, Sekretaris Dinas, 3 orang Kepala Bidang, 2 orang Kepala Seksi, 2 orang Bidan, 2 orang perawat/sanitarian Data dikumpulkan melalui observasi,wawancara dan studi dokumen yang selanjutnya dianalisis dengan teknik kualitatif deskriptif. Hasil penelitian menunjukkan Pengembangan sumber daya manusia pegawai Dinas Kesehatan Kabupaten Kolaka yang dilakukan melalui pengembangan pengetahuan, pengembangan sikap, pengembangan keterampilan, dan pengembangan bakat sudah terlaksana dengan baik, walaupun perlu optimasi secara kongkret dalam bentuk program yang tertuang dalam Renstra Dinas Kesehatan Kabupaten Kolaka. Pengembangan ketahanan pegawai belum terlaksana dengan baik, sehingga diperlukan upaya untuk peningkatan pengembangan ketahanan untuk mengendalikan setiap persoalan yang berimplikasi positif dan bermanfaat bagi produktivitas kinerja serta memperluas kendali dan motivasi pegawai. Kata Kunci : Pengembangan, Sumber Daya Manusia, Pegawai Kesehatan
Komunikasi Bidan Desa Dalam Membangun Kemitraan Dengan Dukun Bayi Dalam Meningkatkan Derajat Kesehatan Ibu dan Anak di Kabupaten Konawe Selatan
Authors: Sriyanti Kiki , Husain Najib , Harmin Sitti 
Published: April 2022

Tujuan penelitian ini adalah untuk mengetahui dan menganalisis komunikasi yang dilakukan oleh Bidan Desa dalam membangun kemitraan dengan Dukun Bayi dalam meningkatkan derajat kesehatan ibu dan anak di Kabupaten Konawe Selatan. Penelitian ini merupakan penelitian kualitatif dengan menggunakan pendekatan etnografi komunikasi. Informan dalam penelitian ini sebanyak 12 orang terdiri dari Bidan Desa dan Dukun Bayi. Prosedur pengumpulan data dilakukan melalui observasi, wawancara mendalam dan dokumentasi. Hasil penelitian menunjukkan bahwa komunikasi Bidan Desa dalam membangun kemitraan dengan Dukun Bayi dilakukan melalui tahap percobaan, yaitu melakukan penjajakan kepada Dukun Bayi melalui pendekatan budaya, memahami identitas Dukun Bayi dalam suatu kelompok masyarakat. Tahap pencocokkan yaitu membangun kesepahaman bersama dengan membagi pengetahuan tentang kesehatan ibu dan anak, menjalankan aturan-aturan yang telah ditetapkan pemerintah, dan membangun kemitraan melalui pembagian peran. Kemudian tahap negosiasi ulang yaitu memastikan hubungan kemitraan tetap berjalan sebagaimana mestinya melalui pendekatan program yang difasilitasi oleh pemerintah daerah. Kata kunci; Komunikasi, Kemitraan, Bidan Desa, Dukun Bayi.
IMPLEMENTASI KEBIJAKAN PEMBERIAN TUNJANGAN PERBAIKAN PENGHASILAN KEPADA PEGAWAI NEGERI SIPIL (STUDI KASUS DI BKPSDM KABUPATEN KOLAKA)
Authors: Uleng Andi Dala , Amir H. Muh. , Gunawan Gunawan 
Published: April 2022

Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis implementasi kebijakan pemberian TPP kepada PNS di Badan Kepegawaian dan Pengembangan Sumber Daya Manusia Kabupaten Kolaka. Penelitian ini menggunakan pendekatan penelitian kualitatif dengan melakukan investigasi pada konteks yang bersifat alamiah. Data dikumpulkan melalui wawancara dan studi dokumen. Teknik analisis data yang digunakan adalah analisis kualitatif model interaktif yang mencakup pengumpulan data yang terintegrasi dengan reduksi data, penyajian data dan penarikan kesimpulan. Teknik pengabsahan data adalah teknik triangulasi jenis dan sumber data, crosschecking, dan memperbanyak deskripsi dan penjelasan. Hasil penelitian menunjukkan bahwa implementasi kebijakan pemberian TPP kepada PNS di Badan Kepegawaian dan Pengembangan Sumber Daya Manusia Kabupaten Kolaka dilihat dari tiga pilarnya yang mencakup pengorganisasian, interpretasi dan aplikasi terlaksana secara kurang optimal, khususnya kemampuan aparat pelaksana level bawah yang mencakup pengetahuan dan keterampilan.Kata-kata kunci: Implementasi; Kebijakan tunjangan perbaikan penghasilan; Determinan implementasi; Struktur birokrasi.
Efficacy of a 6-Week Home-Based Online Supervised Exercise Program Conducted During COVID-19 in Patients With Post Percutaneous Coronary Intervention: A Single-Blind Randomized Controlled Trial
Authors: Li Jiajia , Liu Bo , Wang Zheng , El-Ansary Doa , Adams Roger , Han Jia , Meng Shu 
Published: April 2022

ObjectiveThe aim of this study was to assess the efficacy of a 6-week cardiac rehabilitation (CR) program designed for patients with coronary artery disease (CAD) after percutaneous coronary intervention (PCI) that involved an online supervised exercise program that they could access during COVID-19.MethodsOne hundred patients were randomly allocated into control group (CG) and supervision group (SG). CG accepted conventional health education with a home exercise program booklet delivered before discharge, SG had an additional home-based online supervised exercise program (HOSEP). Questionnaires, motor function and lipid profile were administered at baseline. Questionnaires included the Godin-Shephard Leisure-Time Physical Activity questionnaire (GSLTPAQ) and Bandura's Exercise Self-efficacy (ESE). Motor function included: 6-min walk test (6 MWT), timed up and go test (TUG), 30-s sit to stand (30-s STS), and Hand Grip Strength (HG). Lipid profile included: low-density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC) and triglycerides (TG). The questionnaires were re-administered after 2-weeks, all tests were re-evaluated after 6-weeks.Resultsthe questionnaire results showed that scores on GSLTPAQ and ESE were significantly improved in the SG. The changes in GSLTPAQ scores from baseline to 2- and 6-weeks in the SG were significantly higher than in the CG (2-week: 6.9 ± 13.0 for SG and 0.2 ± 10.2 for CG, p = 0.005; 6-week: 9.4 ± 18.1 for SG and 0.2 ± 11.8 for CG, p = 0.003). in terms of motor function, both the CG and SG improved TUG and 6 MWT performance, with the 6 MWT improvement being significantly greater in the SG than CG (43.7 ± 39.2 m for SG and 16.6 ± 39.1 m for CG, p = 0.001). Improvement in the 30-s STS was significantly greater in the SG than CG (2.4 ± 3.6 repetitions for SG and 0.4 ± 3.5 repetitions for CG, p = 0.007). the lipid profile level significantly improved over baseline in both SG and CG after 6-week intervention, and these changes were not statistically different between groups.ConclusionThis pilot randomized control study demonstrated that a 6-week HOSEP, when added to education delivered pre-hospital discharge for CAD patients following PCI, was beneficial with respect to exercise self-efficacy, exercise behavior, motor function and lipid profile. Supervised exercise programs delivered online in addition to education providing effective and accessible CR during COVID-19.
Optimal Lesion Size Index for Pulmonary Vein Isolation in High-Power Radiofrequency Catheter Ablation of Atrial Fibrillation
Authors: Cai Chi , Wang Jing , Niu Hong-Xia , Chu Jian-Min , Hua Wei , Zhang Shu , Yao Yan 
Published: April 2022

BackgroundAlthough both high-power (HP) ablation and lesion size index (LSI) are novel approaches to make effective lesions during pulmonary vein isolation (PVI) for atrial fibrillation (AF), the optimal LSI in HP ablation for PVI is still unclear. Our study sought to explore the association between LSI and acute conduction gap formation and investigate the optimal LSI in HP ablation for PVI.MethodsA total of 105 consecutive patients with AF who underwent HP ablation guided by LSI (LSI-guided HP) for PVI in our institute between June 2019 and July 2020 were retrospectively enrolled. Each ipsilateral PV circle was subdivided into four segments, and ablation power was set to 50 W with target LSI values at 5.0 and 4.0 for anterior and posterior walls, respectively. We compared the LSI values with and without acute conduction gaps after the initial first-pass PVI.ResultsPVI was achieved in all patients, and the incidence of first-pass PVI was 78.1% (82/105). A total of 6,842 lesion sites were analyzed, and the acute conduction gaps were observed in 23 patients (21.9%) with 45 (0.7%) lesion points. The gap formation was significantly associated with lower LSI (3.9 ± 0.4 vs. 4.6 ± 0.4, p &lt; 0.001), lower force-time integral (82.6 ± 24.6 vs. 120.9 ± 40.4 gs, p &lt; 0.001), lower mean contact force (5.7 ± 2.4 vs. 8.5 ± 2.8 g, p &lt; 0.001), shorter ablation duration (10.5 ± 3.6 vs. 15.4 ± 6.4 s, p &lt; 0.001), lower mean temperature (34.4 ± 1.4 vs. 35.6 ± 2.6°C, p &lt; 0.001), and longer interlesion distance (4.4 ± 0.3 vs. 4.3 ± 0.4 mm, p = 0.031). As per the receiver operating characteristic analysis, the LSI had the highest predictive value for gap formation in all PVs segments, with a cutoff of 4.35 for effective ablation (sensitivity 80.0%; specificity 75.4%, areas under the curve: 0.87). The LSI of 4.55 and 3.95 had the highest predictive value for gap formation for the anterior and posterior segments of PVs, respectively.ConclusionUsing LSI-guided HP ablation for PVI, more than 4.35 of LSI for all PVs segments showed the best predictive value to avoid gap formation for achieving effective first-pass PVI. The LSI of 4.55 for the anterior wall and 3.95 for the posterior wall were the best cutoff values for predicting gap formation, respectively.
Anisotropy of Magnetic Susceptibility Reveals Late Miocene Tectonic Activity in the Western Qaidam Basin
Authors: Zhang Weilin , Li Bingshuai , Yan Maodu 
Published: April 2022

The western Qaidam Basin on the northeastern Tibetan Plateau located at the intersection between the Altyn Tagh Fault and the Kunlun Fault/Qimen Tagh Fault holds significant potential to reveal the tectonic process of these two faults as well as the evolution of the Qaidam Basin. In this paper, we conducted detailed anisotropy of magnetic susceptibility (AMS) records from Late Cenozoic sediments at the Qigequan section in the western Qaidam Basin to shed new light on the tectonic processes in this region. Based on the distribution of three principal axes of magnetic fabrics as well as magnetic fabric parameters, the AMS records can be divided into three parts. The lower part (∼6.9–4.6 Ma), mainly made of fine-grained mudstone and siltstone, exhibits three well-grouped principal axes with a NE-SW elongated Kmin axis as the embryonic tectonic magnetic fabric, suggesting constant NE-SW compressional strain. The middle part (∼4.6–3.0 Ma), characterized by mudstone, siltstone and sandstone, shows three less grouped principal axes and suggests a relatively weak and stable tectonic environment. The three principal axes of the upper part (∼2.4–0.4 Ma) is composed of sandstone and conglomerate of the Qigequan Formation, similar to the middle part, which was primarily attributed to the coarse lithology and not sensitive to tectonics since ∼2.6 Ma. The NE-SW compressional strain in the western Qaidam Basin is consistent with that in the northeastern basin, both of which are parallel to the upper crust movements revealed by the GPS, suggesting the dominant NE-SW compressional strain in the western and northern basins in the late Cenozoic. The decreasing magnitude of tectonic activities during ∼6.9–4.6 Ma indicates that the major geological units released most of the compressional strain in the western Qaidam Basin during tectonic activity that initiated in the early-late Miocene.
Macular Changes Observed on Optical Coherence Tomography Angiography in Patients Infected With Human Immunodeficiency Virus Without Infectious Retinopathy
Authors: Du Kui-Fang , Huang Xiao-Jie , Chen Chao , Kong Wen-Jun , Xie Lian-Yong , Dong Hong-Wei , Wei Wen-Bin 
Published: April 2022

PurposeAs the human immunodeficiency virus (HIV) pandemic is far from over, whether there are subclinical macular changes in HIV-positive patients is something that should not be overlooked. We aimed to apply optical coherence tomography angiography (OCTA) to assess the macular structure and microvasculature changes in patients with HIV without infectious retinopathy.MethodsHIV-positive and -negative participants were included and classified into three groups: HIV-negative, HIV-positive, and HIV-positive with microvasculopathy. OCTA parameters regarding macular structure and microvasculature were analyzed.ResultsCompared with the HIV-negative group, the superficial retinal vessel density (VD) in the parafovea sectors and the whole Early Treatment of Diabetic Retinopathy Study (ETDRS) grid and the choroidal vascularity index (CVI) in the whole ETDRS grid were significantly decreased in the HIV-positive and HIV-positive with microvasculopathy groups (p &lt; 0.05). No differences were found in OCTA parameters between the HIV-positive and HIV-positive with microvasculopathy groups. Retinal, retinal nerve fiber layer-ganglion cell layer-inner plexiform layer (RNFL-GCL-IPL), RNFL, GCL-IPL, and INL thickness showed a negative association with the duration of HIV diagnosis or antiretroviral therapy (ART) (all p &lt; 0.05). All OCTA microvasculature parameters showed no association with HIV-related clinical variables (all p &gt; 0.05).ConclusionsSubclinical macular changes existed in HIV-infected patients without clinical infectious retinopathy. Substructures from inner retinal layers might be associated with HIV infection or ART duration.
Predicting Bone Metastasis Risk Based on Skull Base Invasion in Locally Advanced Nasopharyngeal Carcinoma
Authors: Wu Bo , Guo Yu , Yang Hai-hua , Gao Qian-gang , Tian Ye 
Published: April 2022

ObjectiveTo develop and validate a bone metastasis prediction model based on skull base invasion (SBI) in patients with locally advanced nasopharyngeal carcinoma (LA-NPC).MethodsThis retrospective cohort study enrolled 290 patients with LA-NPC who received intensity-modulated radiation therapy in two hospitals from 2010 to 2020. Patient characteristics were grouped by SBI and hospital. Both unadjusted and multivariate-adjusted models were used to determine bone metastasis risk based on SBI status. Subgroup analysis was performed to investigate heterogeneity using a forest graph. Cox proportional hazard regression analysis was used to screen for risk factors of bone metastasis-free survival (BMFS). A nomogram of BMFS based on SBI was developed and validated using C-index, receiver operating characteristic curve, calibration curves, and decision curve analysis after Cox proportional hazard regression analysis.ResultsThe incidence of bone metastasis was 14.83% (43/290), 20.69% (24/116), and 10.92% (19/174) in the overall population, SBI-positive group, and SBI-negative group, respectively. In the unadjusted model, SBI was associated with reduced BMFS [HR 2.43 (1.32–4.47), P = 0.004], and the results remained stable after three continuous adjustments (P &lt;0.05). No significant interaction was found in the subgroup analyses (P for interaction &gt;0.05). According to Cox proportional hazard regression analysis and clinical value results, potential risk factors included SBI, Karnofsky performance status, TNM stage, induction chemotherapy, concurrent chemoradiotherapy, and adjuvant chemotherapy. Using a training C-index of 0.80 and a validation C-index of 0.79, the nomogram predicted BMFS and demonstrated satisfactory prognostic capability in 2, 3, and 5 years (area under curve: 83.7% vs. 79.6%, 81.7% vs. 88.2%, and 79.0% vs. 93.8%, respectively).ConclusionSkull base invasion is a risk factor for bone metastasis in patients with LA-NPC. The SBI-based nomogram model can be used to predict bone metastasis and may assist in identifying LA-NPC patients at the highest risk of bone metastasis.