bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan Alat Praktikum Kesetimbangan Kimia Untuk Siswa SMA di Pontianak
Authors: Susanti Leni , Fadhilah Raudhatul , Kurniati Tuti 
Published: July 2022

The practicum method in chemistry subjects, especially in chemical equilibrium material, is still rare and has never been carried out in schools due to the unavailability of adequate practicum tools. Therefore, a practical tool is needed to make it more straightforward for understudies to comprehend the idea of equilibrium shift. This study aims to develop a chemical equilibrium practicum tool on the sub-material of equilibrium shift that is legitimate, commonsense and powerful. This sort of exploration is Innovative work (Research and development) model ADDIE (Investigation, Plan, Improvement, Execution, Assessment). The research subjec was 33 students from two private schools in Pontianak, with 15 and 18 students, respectively. The results showed that the chemical equilibrium practicum instrument created from the material and media viewpoints was pronounced substantial with a typical legitimacy worth of 0.87 and 0.9 with both extremely legitimate rules. The consequences of the reasonableness test got extremely down to earth models with a worth of 98.23%. The part of viability by involving the N-Gain esteem in field preliminaries, the N-Gain esteem is 0.8 with extremely high measures. In this manner the synthetic balance practicum instrument created is doable to be utilized as a learning medium in the sub-material of equilibrium shift.
Studi Respon Siswa Terhadap Pengembangan Multimedia Interaktif Berbasis Chemo-Entrepreneurship Berbentuk Aplikasi Android
Authors: Kurnia M. Riyo Agung , Haryanto Haryanto , Sanova Aulia , Dewi Citra Ayu 
Published: July 2022

Chemistry subject is a science that focuses students 1on understanding the principles, theories, concepts and laws of chemistry and their application in real life. Chemo-Entrepreneurship4(CEP) is an approach that links chemistry with real objects. With this approach, students8are expected to be able to learn how to process a material into a valuable and useful product and be able to foster an entrepreneurial spirit. This study aims to develop interactive multimedia based on Chemo-Entrepreneurship in the form of an android application. The design of this study used the Lee & Owens model and involved 10 students of SMA Negeri 10 Tanjung6Jabung Timur. The research instrument used in this study was a questionnaire with analytical techniques in the form of qualitative data analysis and quantitative data analysis. The results of this study include: 1) interactive multimedia developed is declared feasible by media experts and material experts, with a percentage score of 87.2% and 88.57% respectively, 2) interactive multimedia is declared feasible based on the teacher's assessment with a percentage a score of 91.4%, 3) get a percentage of student responses of 94% with a very good category. Thus, it can be concluded that the student response is very positive to the chemo-entrepreneurship-based interactive multimedia that has been developed.
Da viabilidade de fabrico de vidro com resíduos de mineração
Authors: Ramos Kerollan da Silva , Luz José Aurélio Medeiros da , Milhomem Felipe de Orquiza 
Published: July 2022

Os resíduos gerados pela mineração tem sido majoritariamente estocados em barragens ou pilhas, gerando altos custos para sua gestão. O presente trabalho teve o intuito de, primeiramente, verificar a adequação de resíduos de mineração como matéria-prima para produção de vidro e avaliar economicamente o seu emprego, citando as principais características do fabrico do vidro, e simulando a implantação de uma fábrica de vidro, no âmbito de políticas públicas de aproveitamento de resíduos sólidos. Num primeiro estágio, ensaios prospectórios de laboratório, com base na revisão da literatura, mostraram a exequibilidade técnica do emprego de resíduos de mineração da região de Ouro Preto (MG, Brasil) para o fabrico de vidro. A seguir foi feita uma orçamentação expedita de fábrica de elaboração de vidro sílica-cal-soda para dois cenário produtivos, a saber: de 15 t/dia e 400 t/dia. Conclui-se pela viabilidade econômica desse tipo de empreendimento, que, entretanto, exige grande investimento de capital, demonstrando ser muito valioso o apoio de órgãos de fomento governamentais para a sua implantação.
Hábitos alimentares de crianças e adolescentes e repercussões no decurso da pandemia do Covid-19
Authors: Lima Caroline Teixeira , Abreu Diogo Rafael Vieira Santana de , Bezerra Keila Cristiane Batista , Landim Liejy Agnes dos Santos Raposo , Santos Livia Cristina Lima dos 
Published: July 2022

Objetivo: este trabalho tem o intuito verificar na literatura publicações sobre os hábitos alimentares de crianças durante a pandemia do Covid-19. Metodologia: constitui-se de um estudo de revisão integrativa da literatura, de natureza qualitativa e exploratória, com abordagem teórica. No qual foi empregado, o recorte temporal de dois anos para a seleção de artigos originais em português e inglês. Resultados: os impactos causados pela pandemia do Covid-19 nos hábitos alimentares de crianças e adolescentes, implicam em maiores alterações negativas do que positivas no âmbito da saúde. Conclusão: os estudos catalogados denotaram elevação do peso corporal, aumento do consumo de alimentos de alta densidade energética, reduzida prática de atividade física, maior tempo de uso de celular, computador, televisão e tablet, desencadeando piora na postura e má qualidade de sono de crianças e adolescentes durante o isolamento social. Consideramos imprescindível executar novos estudos de intervenção para combater a problemática do excesso e peso e obesidade, tendo em vista, que as consequências de um curto espaço de tempo da pandemia, não são os causadores dessas problemáticas de saúde, distúrbios recorrentes antes da pandemia.
Effect of Maternal Antidepressant Use During the Pre-pregnancy/Early Pregnancy Period on Congenital Heart Disease: A Prospective Cohort Study in Central China
Authors: Sun Mengting , Zhang Senmao , Li Yihuan , Chen Letao , Diao Jingyi , Li Jinqi , Wei Jianhui , Song Xinli , Liu Yiping , Shu Jing , Wang Tingting , Huang Peng , Qin Jiabi 
Published: July 2022

BackgroundWith the increase in maternal antidepressant prescribing before/during pregnancy, concerns about the safety of antidepressants have come into focus. The purpose of this study was to explore the association between maternal antidepressant use before pregnancy/in early pregnancy and the risk of congenital heart disease (CHD) in children, and to provide a scientific basis for clinical safety of antidepressant use.MethodsThe prospective cohort study ultimately included 34,104 singleton pregnancies. Modified Poisson regression model with robust error variances was used to evaluate RRs and 95% confidence intervals (CIs) for the risk of CHD in offspring exposed to maternal antidepressant in the 3 months before pregnancy and early pregnancy. In addition, sensitivity analysis was further performed to explore the robustness of the results.ResultsIn this study, the maternal antidepressant exposure rate was 2.83% in the 3 months before pregnancy, 2.42% in early pregnancy, and the incidence of CHD was 8.973 per 1,000 live births. We found that maternal antidepressant use in the 3 months before pregnancy and early pregnancy were all associated with an increased risk of CHD, ~2.54 times and 2.87 times, respectively, of non-use of antidepressants after adjusting for potential confounders. This association was also found in CHD specific phenotypic analysis. Of these, offspring whose mothers were exposed to antidepressants in the 3 months before pregnancy had the highest risk of transposition of the great arteries (aOR = 5.50, 95% CI: 1.91–15.88). The offspring of mothers exposed to antidepressants in early pregnancy had the highest risk of developing ventricular septal defect (aOR = 4.80, 95% CI: 2.50–9.24). Sensitivity analysis verified the stability of the results.ConclusionsMaternal antidepressant use in the 3 months before pregnancy and early pregnancy were all associated with an increased risk of CHD in their offspring. In order to reduce the risk of teratogenesis, we recommend that pregnant women prepare for pregnancy after their condition improves or receive the minimum effective dose of medication.
Micro Plant Remains Reveal the Function of Grooved Pottery Vessels From the Late Neolithic Meishan Site in Central China
Authors: Wang Tao , Zang Yafan , Ma Zhikun , Yang Jishuai , Yuan Guangkuo , Yang Xiaoyan 
Published: July 2022

From 6,000 calendar years before the present (cal BP) onward, grooved pottery vessels occurred in the lower and middle reaches of the Yangtze River in succession. After a thousand years, it was introduced into central China and became popularized there around 4,000 years ago. It has been proposed that the function of the grooved vessels was to process plant foods, replacing the previously used stone slabs and rollers in terms of ethnographic investigation, but there is a lack of solid and direct evidence although little evidence of starches has been provided. Here we report our study on the sherds of grooved vessels from the Meishan site in central China (late Longshan and Erlitou period). The combined starch and phytolith analyses were first used together to examine the residues on the sherds. Starches from geophytes, millets (Setaria italica and Panicum miliaceum), wheat (Triticum aestivum), and phytoliths from the glumes and leaves of these crops plus rice (Oryza sativa), seem to suggest that the grooved pottery vessels were likely to be used to grind geophytes and dehusk grain seeds. But, incorporating the extremely low proportion of grooved vessels to entire pottery tools at the site, we hypothesize that the invention of grooved vessels may have been related to the success of rice domestication and may have been used as tools to pound by-products of crops, leaves, and husks somehow.
A Novel and Effective Model to Predict Skip Metastasis in Papillary Thyroid Carcinoma Based on a Support Vector Machine
Authors: Zhu Shuting , Wang Qingxuan , Zheng Danni , Zhu Lei , Zhou Zheng , Xu Shiying , Shi Binbin , Jin Cong , Zheng Guowan , Cai Yefeng 
Published: July 2022

IntroductionSkip metastasis, referred to as lymph node metastases to the lateral neck compartment without involvement of the central compartment, is generally unpredictable in papillary thyroid carcinoma (PTC). This study aims to establish an effective predictive model for skip metastasis in PTC.Meterials and MethodsRetrospective analysis was performed of clinical samples from 18192 patients diagnosed with thyroid cancer between 2016 to 2020. The First Affiliated Hospital of Wenzhou Medical University. The lateral lymph node metastasis was occureed in the training set (630 PTC patients) and validation set (189 PTC patients). The univariate and multivariate analyses were performed to detect the predictors of skip metastasis and the support vector machine (SVM) was used to establish a model to predict skip metastasis.ResultsThe rate of skip metastasis was 13.3% (84/631). Tumor size (≤10 mm), upper location, Hashimoto’s thyroiditis, extrathyroidal extension, absence of BRAFV600E mutation, and less number of central lymph node dissection were considered as independent predictors of skip metastasis in PTC. For the training set, these predictors performed with 91.7% accuracy, 86.4% sensitivity, 92.2% specificity, 45.2% positive predictive value (PPV), and 98.9% negative predictive value (NPV) in the model. Meanwhile, these predictors showed 91.5% accuracy,71.4% sensitivity, 93.1% specificity, 45.5% PPV, and 97.6% NPV in validation set.ConclusionThis study screened the predictors of the skip lateral lymph node metastasis and to establish an effective and economic predictive model for skip metastasis in PTC. The model can accurately distinguish the skip metastasis in PTC using a simple and affordable method, which may have potential for daily clinical application in the future.
Innovation and Recycling—Drivers of Circular Economy in EU
Authors: Platon Victor , Pavelescu Florin Marius , Antonescu Daniela , Frone Simona , Constantinescu Andreea , Popa Florina 
Published: July 2022

In our days, a growing attention is paid to explain the influence of innovation on recycling. While many studies on this subject have been carried out, it's still needed for more investigations on measuring the effect of innovation on recycling. This paper is dedicated to measuring the intensity of the innovation influence on the recycling within EU member states. The methodology follows the next steps: visualization of data used, determining the stationarity of the time series analyzed, developing a panel model for 28 countries, applying specific statistical tests in case of the two indicators selected. After analyzing the models that resulted and applying Hausman test, the authors concluded that the regression panel with fixed effects is appropriate for our research. Thus, it is possible to show that the influence of the innovation on recycling is moderate and not instantaneous because there is manifested a lag of 2 years. In addition, the Fixed Effects model allows highlighting the heterogeneity that is present among member states. In addition, the authors concluded that the membership of the Euro Area has a positive influence on recycling and on circular economy as well. The article has several originality aspects: it took into account criteria that are not discussed very often as membership of Euro area; it has developed a model that brings quantitative aspects to describe the influence of innovation on recycling, it highlighted the heterogeneity existing among EU member states. Future research direction would be to consider including in the model some other variables as eco-investment.
Response of Sheet Erosion to the Characteristics of Physical Soil Crusts for Loessial Soils
Authors: Liu June , Qi Xiaoqian , Ma Chunyan , Wang Zhanli , Li Haohong 
Published: July 2022

The influences and quantifications of soil crust traits on the infiltration, hydrodynamic of runoff, and erosion rate of sheet erosion under the combined effects of raindrop impact and sheet flow scouring need further study. Loessial soil from the Loess Plateau was tested to produce different antecedent crusts under simulated rainfall intensities (0.5, 1.0, 1.5, 2.0, and 2.5 mm/min, typical storm intensity in the area), and then the effects of antecedent crusts on sheet erosion processes were quantified at a rainfall intensity of 1.5 mm/min. The results showed that the bulk density and hardness of antecedent crusts were higher than those of soil. Particle sizes of crusts were smaller than those of soil at light rain intensity but larger under heavy rain intensity. The bulk density, hardness, and particle size D50 of the antecedent crust were all positively correlated with rainfall intensity, being well described by linear equations (R2 &gt; 0.87), while the thickness was negatively linearly correlated with rainfall intensity (R2 = 0.88). Although the existence of antecedent crusts could decrease the infiltration and increase the runoff, resulting in the high flow velocity and stream power, antecedent crusts could still effectively reduce sheet erosion. The reductions in the average infiltration rate and average erosion rate and the increases of average flow velocity and stream power all increased with the increment of bulk density of antecedent crust. Relationships could be all well described by linear positive correlations (R2 &gt; 0.79). When the bulk density of crust was enhanced by 27∼29%, the flow velocity and stream power could be increased by 8∼29% and 15∼70%, and the sheet erosion could be reduced by 61∼73%. The existence of crust could effectively reduce sheet erosion. These results could help understand the mechanism of the erosion process in the presence of physical crusts.
The Challenges of Vision Zero Implementation in Iran: A Qualitative Study
Authors: Safarpour Hamid , Khorasani-Zavareh Davoud , Soori Hamid , Ghomian Zohreh , Bagheri-Lankarani Kamran , Mohammadi Reza 
Published: July 2022

Background: Road traffic crashes’ (RTCs) multidimensional nature has piqued the interest of officials all around the world for many years. Vision Zero is one of the most innovative approaches to road safety. Vision Zero is a government initiative aimed at reducing RTC-related deaths and serious injuries. To effectively apply this approach in Iran, it is required to first identify the obstacles to execution. Therefore, the purpose of this study was to examine the obstacles to Vision Zero implementation in Iran.Methods: The qualitative content analysis method was used in this investigation. The participants were chosen using purposive, snowball, and maximum variety sampling methods. Data were collected through face-to-face interviews. Graneheim and Lundman’s method was used to analyze data using the content analysis method.Results: There were 16 interviews with 14 participants in this study. The data were organized into four main categories and 13 sub-categories to determine the obstacles to implementing Vision Zero. Managerial and administrative obstacles, as well as supportive, cultural, and social, and transportation design and development challenges, were the main categories.Conclusion: In Iran, implementing Vision Zero necessitates the establishment of a lead agency that considers administrative and managerial, supportive and logistic, socio-cultural, transportation design and development, and infrastructure components. In addition, Vision Zero implementation and road safety improvement would require political commitment and support from the government and society. Vision Zero implementation and road safety management must take into account the ethics and value of human life.
Sol–Gel Synthesis and Photocatalytic Activity of Graphene Oxide/ZnFe2O4-Based Composite Photocatalysts
Authors: Tong Beibei , Shi Longfei , Liu Xiaohong 
Published: July 2022

ZnO (ZO), Fe2O3 (FO), and graphene oxide (GO)/ZO/FO/ZnFe2O4 (ZFO) composite photocatalysts have been synthesized successfully via a simple sol–gel method and low-temperature technology. The phase structure and microstructural analysis confirmed that the GO/ZO/FO/ZFO magnetic separation photocatalyst is composed of GO, hexagonal ZnO, rhombohedral Fe2O3, and spinel ZnFe2O4 without any other impurities. The GO/ZO/FO/ZFO composite photocatalysts have a high visible light optical absorption coefficient and photocatalytic activity for degrading dyes, refractory pollutants, and antibiotics. The degradation percentages of methyl orange, tetrabromobisphenol A, and oxytetracycline hydrochloride by the GO/ZO/FO/ZFO magnetic separation photocatalyst were 98% for 180 min, 99% for 150 min, and 85% for 180 min, respectively. The special synthesis path leads to the formation of a special heterojunction between GO, ZnO, Fe2O3, and ZnFe2O4, which does not change the optical band gap value of the main lattice Fe2O3, and enhances the surface defects of the GO/ZO/FO/ZFO magnetic separation photocatalyst, resulting in high charge carrier transfer and separation efficiency of the catalyst and then enhanced the photocatalytic activity of the GO/ZO/FO/ZFO magnetic separation photocatalyst.
Vitamin D 25OH Deficiency and Mortality in Moderate to Severe COVID-19: A Multi-Center Prospective Observational Study
Authors: Bogliolo Laura , Cereda Emanuele , Klersy Catherine , Stefano Ludovico De , Lobascio Federica , Masi Sara , Crotti Silvia , Bugatti Serena , Montecucco Carlomaurizio , Demontis Stefania , Mascheroni Annalisa , Cerutti Nadia , Malesci Alberto , Corrao Salvatore , Caccialanza Riccardo ,   The NUTRI-COVID19 Collaborative Working Group
Published: July 2022

IntroductionSeveral studies and meta-analyses suggested the role of vitamin D 25OH in preventing severe forms of coronavirus disease 2019 (COVID-19). However, the evidence on the clinical benefits of vitamin D 25OH adequacy in patients hospitalized for COVID-19 remain conflicting and speculative. We aimed to investigate the association between vitamin D 25OH serum levels and mortality in hospitalized patients with moderate to severe COVID-19.MethodThis prospective observational multicentre study included 361 consecutive patients with moderate to severe COVID-19 admitted to the Italian hospitals involved in the NUTRI-COVID19 trial from March to August 2020. For each patient, serum vitamin D 25OH levels were assessed 48 h since admission and classified as deficient (&lt;20 ng/mL) or adequate (≥20 ng/mL). We built a propensity score for low/adequate vitamin D 25OH levels to balance the clinical and demographic properties of the cohort, which resulted in 261 patients with good common support used for the survival analysis.ResultsTwo Hundred-seventy-seven (77%) of the 361 enrolled patients (207 [57%] males, median age 73 ± 15.6 years) had vitamin D 25OH deficiency. Fifty-two (20%) of the 261 matched patients died during the hospital stay, corresponding to a hazard ratio of 1.18 for vitamin D 25OH deficiency (95% confidence interval: 0.86–1.62; p = 0.29).DiscussionThe prevalence of vitamin D 25OH deficiency was confirmed to be very high in hospitalized patients with COVID-19. The use of a propensity score demonstrate an absence of significant association between vitamin D deficiency and mortality in hospitalized patients.