bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengembangan RUTF (Ready to Use Therapeutic Food) Berbahan Serealia dan Kedelai bagi Balita Malnutrisi Akut Berat<br><i> Produk Development of RUTF (Ready to Use Therapeutic Food) Using Cereals and Soybean for Children with Severe Acute Malnutrition </i></br>
Authors: Mentari Anisa Dewi , Setiawan Budi , Palupi Eny 
Published: February 2022

Malnutrisi akut pada kelompok usia balita masih menjadi masalah gizi serius di Indonesia. Sebanyak 10,4% balita di Indonesia mengalami malnutrisi akut dengan 3,5% diantaranya tergolong malnutrisi akut berat. RUTF (Ready to Use Theurapetic Food) merupakan makanan pemulihan yang sudah terbukti efektif menanggulangi masalah malnutrisi akut berat. Pemberian RUTF di Indonesia belum menyeluruh dan masih diperoleh secara import, sehingga perlu adanya inovasi dalam mengembangkan RUTF dengan memanfaatkan pangan lokal. Tujuan dari penelitian ini adalah mengembangkan dan menganalisis zat gizi produk pasta RUTF berbasis pangan lokal yang terdiri dari beras, jagung, kedelai dan tempe untuk menanggulangi masalah status gizi balita yang mengalami malnutrisi akut berat. Desain dari penelitian ini adalah eksperimental menggunakan Rancangan Acak Lengkap Faktorial dengan dua kali ulangan. Terdapat dua faktor perlakuan, yaitu jenis serealia dan jenis kacang. Masing-masing faktor terdiri dari dua taraf, yaitu beras dan jagung (Faktor A) serta kedelai dan tempe (Faktor B). Penelitian ini terdiri dari empat formula, yaitu A1B1 (beras-kedelai), A2B1 (jagung-kedelai), A1B2 (beras-tempe), A2B2 (jagung-tempe). Formula dengan perpaduan beras dan kedelai (A1B1) dipilih sebagai formula terbaik berdasarkan hasil organoleptik, kandungan protein dan daya cerna protein in vitro. Hasil analisis kimia pasta RUTF terpilih mengandung kadar air 1,87%, abu 2,80%, protein 14,35%, lemak 32,50%, karbohidrat 45,29%, energi 531 kkal, serat pangan 3,19%, Fe 13,99 mg/100 g, Ca 395,73 mg/100 g dan daya cerna protein in vitro 95,47%. Secara keseluruhan, nilai zat gizi formula terpilih telah memenuhi persyaratan yang direkomendasikan oleh WHO, sehingga produk ini dapat menjadi alternatif untuk mengatasi masalah manutrisi akut berat pada balita.
Acenocoumarol induced anticoagulant-related nephropathy with newly diagnosed IgA nephropathy: A repeat biopsy case report
Authors: CHALKIA AGLAIA , Dimitrios Kourniotis , George Aggelis , Harikleia Gakiopoulou , Dimitrios Petras 
Published: February 2022

Abstract
Anticoagulant-related nephropathy (ARN) is an underestimated cause of acute kidney injury (AKI) with poor renal and overall prognosis. Pathogenesis is not fully elucidated yet, although AKI is probably resulting from glomerular hemorrhage and most commonly has been described in patients with glomerular lesions, that alter the glomerular permeability, and conditions with glomerular hyperfiltration. Herein, we describe a case with a 58-year-old man who presented with macroscopic hematuria and AKI, and recently taking acenocoumarol for aortic valve replacement. The first renal biopsy showed red cell casts in the renal tubules, one glomerular crescent formation in the glomeruli with mild immunoglobulin A deposition, and severe interstitial inflammation. Based on these findings, the patient was diagnosed with acenocoumarol induced ARN with newly diagnosed IgA nephropathy and switched to tinzaparin with a short course of corticosteroids. Renal improvement in ARN is usually partial and is delayed, as confirmed by a second biopsy in our patient after six months.
An efficient 110 x 8 GHz WDM RoF System design for 5G &amp; advance wireless networks
Authors: Nain Abhimanyu , Garg Deepak 
Published: February 2022

Abstract
High speed networks over long distance with superior transmission efficiency is the need & demand of current and next generation networks. For which, millimetre wave (mm-wave) based many Radio over Fiber (RoF) networks are proposed earlier with several modulation and multiplexing techniques. This paper presents an efficient RoF network comprising of cascaded combination of an Mach

Zehnder Modulator (MZM) & a Li-Nb MZM in transmitter alongwith Optical Phase Conjugator (OPC) in the link to improve the extensive bandwidth quality transmission over longer distances. The proposed model reports successful transmission of 8 channel WDM signal with RF signal of 110 GHz over a range of 100 km at 12 Gbps data rate. The model provides an average Bit Error Rate (BER) of 10^(−58) and an average Q-factor of 15.64 when channel spacing is kept at 0.5 nm.
Factors Influencing Successful Coping among Crime Scene Investigation (CSI) Personnel: Recruiting for Resilience - A Mixed Methods Study
Authors: Craven Helen , Hallmark Michelle , Holland Fiona , Maratos Frances 
Published: February 2022

Abstract
Successful coping is important for staff wellbeing, retention and reducing absenteeism, especially for those employed in high emotional labour jobs such as crime scene investigation (CSI). Antecedents of successful coping can include self-efficacy, locus of control, optimism, resilience, and self-esteem. However, a dearth of literature exists attaining to the importance of emotion-regulation and mindfulness for successful coping in these roles, despite evidence revealing both are conducive to better wellbeing. Additionally, few studies with CSI personnel have employed a mixed-methods approach, which enables exploration of lived experiences. Here, we recruited 84 CSI employees and 88 students undertaking a degree enabling employment within CSI, to comprehensively explore factors predicting successful coping. 75 CSI employees and 88 students took part in the quantitative aspect, where questionnaire data pertaining to the above wellbeing factors, as well as depression, anxiety and stress, were collected. Nine CSI employees took part in the qualitative aspect. This included deeper exploration of resilience and coping, including how CSI personnel manage their occupation. Quantitative analyses revealed that, for CSI personnel, the greatest predictors of successful coping were resilience and emotional regulation. Compared to students, CSI personnel further reported greater self-esteem, optimism, coping self-efficacy, mindfulness and resilience; and fewer difficulties in emotion regulation, depression, anxiety and stress. Qualitative analyses also revealed resilience/emotion-regulation to be key coping factors; but additionally, that finding meaning in work/collegiate support enabled successful coping. Potential implications of findings are discussed and include pre-employment screening for emotion regulation and resilience, and inclusion of such in CSI training/CPD curricula.
Significance of Predicted Future Liver Remnant Volume on Liver Failure Risk after Major Hepatectomy: A Case Matched Comparative Study
Authors: Piccus R , Joshi K , Hodson J , Bartlett D , Chatzizacharias N , Dasari B , Isaac J , Marudanayagam R , Mirza DF , Roberts JK , Sutcliffe RP 
Published: February 2022

Abstract
IntroductionFuture liver remnant volume (FLRV), a risk factor for liver failure (PHLF) after major hepatectomy (MH), is not routinely measured. This study aimed to evaluate the association between FLRV and PHLF.Patients and methodsAll patients undergoing MH (4+ segments) between 2011-2018 were identified from a prospectively maintained single-centre database. Perioperative data were collected for patients with PHLF, who were matched (1:2) with non-PHLF controls. FLRV and FLRV% (i.e. % of total liver volume) were calculated retrospectively from preoperative CT scans using Synapse-3D software, and compared between the PHLF and matched control groups.Results Of 711 patients undergoing MH, PHLF occurred in 27 (3.8%), of whom 24 had preoperative CT scans available. These patients were matched to 48 non-PHLF controls, 98% of whom were classified as being at high risk of PHLF on preoperative risk scoring. FLRV% was significantly lower in the PHLF group, compared to matched controls (median: 28.7 vs. 35.2%, p=0.010), with FLRV% < 30% in 58% and 29% of patients, respectively. Assessment of the ability of FLRV% to differentiate between PHLF and matched controls returned an area under the ROC curve of 0.69, and an optimal cut-off value of FLRV% < 31.5%, which yielded 79% sensitivity and 67% specificity. ConclusionsFLRV% is significantly predictive of PHLF after MH, with over half of patients with PHLF having FLRV% < 30%. In light of this, we propose that all patients should undergo risk stratification prior to MH, with the high risk patients additionally being assessed with CT volumetry.
A smart-device based secondary prevention program for cerebrovascular disease patients: a randomized trial
Authors: Motolese Francesco , Capone Fioravante , Magliozzi Alessandro , Vico Carlo , Iaccarino Gianmarco , Falato Emma , Pilato Fabio , Lazzaro Vincenzo Di 
Published: February 2022

Abstract
Background: Commercially available health devices are always more common and represent a unique chance to monitor patients for prolonged periods. This study aimed to test the feasibility of a smart device-based secondary prevention program in a cohort of patients with undetermined aetiology cerebrovascular disease.Methods: Patients with non-disabling ischemic stroke and transient ischemic attack in the subacute phase were provided with a smartwatch and smart-devices to monitor various vital parameters for a 4-week period (watch group). This group was compared with a standard-of-care group. This clinical trial was registered with ClinicalTrials.gov, ID: NCT04282993.Results: In total, 161 patients were recruited, 87 in the Watch group and 74 in the control group. In the watch group, more than 90% of patients recorded the ECG at least once a day. In total, 5335 ECGs were recorded during the study. The median value of blood pressure measurements was 132 over 78 mmHg. The median oxygen saturation value was 97 %. From a clinical standpoint, nine AF episodes (10,3%) in the Watch group – vs 3 (4%) in the control group - were detected.Conclusion: Our study suggests that prevention programs for cerebrovascular disease may benefit from the implementation of new technologies.
Assessment of microcystins in surface water and irrigated vegetables in Kwaru stream, Hayin Danmani, Kaduna-Nigeria
Authors: Abdullahi Halima , Tanimu Yahuza , Akinyemi Suwebat Ayanronke , Bittencourt-Oliveira Maria do Carmo , Chia Mathias Ahii 
Published: February 2022

Abstract
Microcystins (MCs) are hepatotoxic secondary metabolites produced by several genera of cyanobacteria. Human exposure routes include drinking contaminated water and consuming contaminated fish, vegetables, crops, and even food supplements that contain cyanotoxin. This study investigated the presence of MCs in a stream with a long history of use as a source of water for irrigation farming. To establish the risk of lack of monitoring programs, we studied MCs contamination of irrigated vegetables. Toxin levels in the water were generally <0.05 µg L-1 in all the investigated stations. Total microcystin concentrations in spinach (0.306 µg Kg-1 upstream and 0.217 µg Kg-1 downstream), lettuce (0.085 µg Kg-1 upstream and 0.462 µg Kg-1 downstream), carrot (0.050 µg Kg-1 downstream and 0.116 µg Kg-1 downstream), cabbage (0.014 µg Kg-1 upstream and 0.031 µg Kg-1 downstream), tomatoes (0.233 µg Kg-1 upstream) and bitter leaf (0.460 µg Kg-1 upstream and 0.050 µg Kg-1 downstream) collected in March were higher than the levels detected in samples of the same vegetables collected in April. These results highlight Nigeria's severe public health problem, especially in regions with long dry season spells. The level of MCs contamination of irrigated vegetables implies a potential for chronic exposure and associated health challenges.
Unveiling microscopic carrier loss mechanisms in 12% efficient Cu2ZnSnSe4 solar cells
Authors: Li Jianjun , Huang Jialiang , Ma Fa-jun , Sun Heng , Cong Jialin , Privat Karen , Yao Yin , Chin Robert , He Mingrui , Sun Kaiwen , Li Hui , Mai Yaohua , Hameiri Ziv , Ekins-Daukes Ned , Tilley Richard , Unold Thomas , Green Martin , Hao Xiaojing 
Published: February 2022

Abstract
Carrier loss mechanisms at microscopic regions is imperative for high-performance polycrystalline inorganic thin-film solar cells. Despite the progress on Kesterite, a promising environmental-benign and earth-abundant thin-film photovoltaic material, the microscopic carrier loss mechanisms and their impact on device performance remain unknown. Herein, we unveil these mechanisms in state-of-the-art Cu2ZnSnSe4 (CZTSe) solar cells using a framework that links microscopic-structural and optoelectronic characterizations with three-dimensional device simulations. The results indicate the CZTSe films have an encouraging intragrain minority carrier lifetime of >10 ns, a marginal radiative recombination loss through sub-band recombination and electrostatic potential fluctuation, whilst a large effective grain boundary recombination velocity of around 104 cm s-1 and a low net carrier density of ~1×1015 cm-3. We identify that severe grain boundary recombination and low net carrier density are the current limiting factors of device performance. The established framework can greatly advance the research of kesterite and other emerging photovoltaic materials.
Synthesis and assessment of novel self-doped poly (5-nitro-orthanilic acid) as a multifunctional scaling inhibitor on controlling the precipitation and crystal growth of CaCO3 and CaSO4 in solution
Authors: Hassan Hammed H. A. M. , Abd-El-Khalek Dalia E. , Fattah Marwa Abdel 
Published: February 2022

Abstract
Self-doped-and nitro-polyanilines have become a widely used strategy to optimize the electronic and vibratory spectra of polymeric building blocks in various applications. We report the synthesis of poly (5-nitro-orthanilic acid) by an aniline-initiated oxidative polymerization reaction. The polymer is characterized by spectroscopic techniques, elemental shapes, cyclic voltammetry, electrical conductivity, microscopic and thermal measurements. The hydrophilic and hydrophobic nature of the supports provided the formation of amphiphilicity as judged by SEM. Thermo-gravimetric measurements reveal thermal stability up to 500 °C and glass temperature (Tg) observed at 240 °C. Electrical conductivity decreases as the temperature rises at the different frequencies used, reflecting the semiconducting nature in the extrinsic range, which is characterized by high carriers and low mobility. The presence of these electron residues causes a decrease in efficiency and increases the thermal conductivity. Dielectric measurements have shown that permittivity decreases gradually at lower levels, mainly due to the transport of charging carriers, resulting in higher performance. The testing of the copolymer as a new scale blocker has resulted in moderate to fairly high performance. This effect is attributed to the change in polymer geometry using intramolecular H-bonding group-SO3H and a chain polymer in an aqueous medium.
Prevalence of Wasting and Associated Factors Among Children Aged 6-23 Months in Garowe, Puntland, Somalia
Authors: Abdiwali Abdulahi , Gebremichael Berhe , Gebretsadik Solomon , Roba kedir Teji 
Published: February 2022

Abstract
Background: Child wasting is one of the most serious public health problems in developing countries, including Somalia. It affects child growth and development. If not treat early it causes chronic malnutrition than will affects brain development and can cause premature death of the children. However, there is limited evidences regarding child wasting in Somalia and no study in Puntland in particular. Therefore, this study was designed assess the prevalence of wasting and associated factors among children aged 6-23 months in Garowe Town, Puntland, Somalia. Methods: A community based cross-sectional study was conducted using pre-tested questionnaire among 409 children aged 6-23 months, from June 05-15, 2021. A systematic random sampling technique was used to select study participants. The collected data were entered and cleaned using EpiData version 3.1 and then exported into statistical package for social science (SPSS) version 20 for analysis. Both bivariable and multivariable logistic regression models were employed to identify factors associated with wasting. Variables having p-value <0.05 were considered to be significantly associated with the dependent variable. The adjusted odds ratio (AOR) with 95% confidence interval (CI) was used to show the presence, strength and direction of associations. Results: The prevalence of wasting among children aged 6-23 months was 34.2%, (95%CI 28.7 CI, 40.3); of which, 12% were severely wasted. Being from daily laborer father (AOR=3.1, 95% CI: (1.1, 8.7)), initiating complementary feeding before six months (AOR=8, 95% CI: (4.5, 14)) , breastfeeding initiation after some hour of birth (AOR=3.9, 95% CI: (1.8, 8.4)), being unvaccinated (AOR=2.9, 95% CI:(1.7, 5.2)), mother with no formal education (AOR=3.4, 95% CI: (1.6, 7.0)) and mothers who didn’t attend ANC follow-up during last pregnancy (AOR=5.3, 95% CI: (2.9, 9.5) were significantly associated with occurrence of wasting among children aged 6-23 months.Conclusions: The prevalence of wasting among children aged 6-23 months in the study area is serious public health problem. Therefore, to reduce the incidence of malnutrition, ministry of health should work closely with all health facilities in the country, as well as improve the quality of health workers and strengthen maternal and child health care.
Latent, early or late HHV-6B expression in adult mesial temporal lobe epilepsy: Association of virus life cycle with inflammatory cytokinesin brain tissue and cerebral spinal fluid
Authors: Wang Jiaqi , Yang Hong-Yu , Shao Xue , Jiang Xin-Yue , Li Jinmei 
Published: February 2022

Abstract
Background: Human herpes virus-6B (HHV-6B) was suggested as an important etiologic factor of mesial temporal lobe epilepsy, while the mechanism is still unknown. Here, we aimed to analyze antigens representing latent, early and late HHV-6B infection and the association with inflammatory cytokines in brain tissue and cerebral spinal fluid (CSF) from MTLE patients with HHV-6B-positivity.Results: Nested polymerase chain reaction (nPCR) in brain tissue revealed HHV-6B DNA in 19 of 49 MTLE patients (39%) and 1 of 19 controls (5%) (P<0.001), but not in CSF. ICH showed HHV-6B early antigen (P41) positivity in 3 patients (6%), late antigen (gp116/54/64) positivity in 5 patients (10%), latent antigen (U94) positivity in 8 patients (16%), and multiple antigen (early and late or/and latent) positivity in 9 patients (18%). None of these HHV-6B related proteins were found positive in control brain tissue. PCR revealed significant up-regulation of IL-1a, IL-2 and IL-7 mRNA levels in brain tissue from MTLE patients with different virus state. Suspension bead array in CSF confirmed significant up-regulation of IL-1a and IL-7 protein expression.Conclusions: Our finding suggests HHV-6B is a common etiologic agent of MTLE. Different virus life cycle may play an important modifying role in inflammatory biology that warrants further investigation. Though virus DNA is difficult detected in CSF, up-regulation of IL-1a and IL-7 in CSF indicates the two cytokines may be taken as indirect biomarker of HHV-6B infection.
Rethinking Statistical Learning as a Dynamic Stochastic Process, from The Motor Systems Perspective
Authors: Torres Elizabeth , Vaskevich Anna 
Published: February 2022

Abstract
The brain integrates streams of sensory input and builds accurate predictions, while arriving at stable percepts under disparate time scales. This stochastic process bears different dynamics for different people, yet statistical learning (SL) currently averages out, as noise, individual fluctuations in data streams registered from the brain as the person learns. We here adopt the motor systems perspective to reframe SL. Specifically, we rethink this problem using the demands that the person’s brain faces to predict, and control variations in biorhythmic activity akin to those present in bodily motions. This new approach harnesses gross data as the important signals, to reassess how individuals learn predictive information in stable and unstable environments. We find two types of learners: narrow-variance learners, who retain explicit knowledge of the regularity embedded in the stimuli -the goal. They seem to use an error-correction strategy steadily present in both stable and unstable cases. In contrast, broad-variance learners emerge only in the unstable environment. They undergo an initial period of memoryless learning characterized by a gamma process that starts out exponentially distributed but converges to Gaussian. We coin this mode exploratory, preceding the more general error-correction mode characterized by skewed-to-symmetric distributions and higher signal content from the start. Our work demonstrates that statistical learning is a highly dynamic and stochastic process, unfolding at different time scales, and evolving distinct learning strategies on demand.
Specific Antibody Titer Decay in Neonates Prenatally Exposed to Toxoplasma Gondii and Their Mothers.
Authors: Salomè Serena , Grieco Claudia , Barra Pasquale Fabio , Capone Eleonora , Grasso Fiorentino , Carraturo Francesca , Dolce Pasquale , Salvatore Paola , Capasso Letizia , Raimondi Francesco 
Published: February 2022

Abstract
Backgrounds: For infants exposed in utero to Toxoplasma gondii, current guidelines recommend monitoring the specific antibody titer until 12 months of age. In this study, we investigated the antibody titer decay in the mother-infant dyad.Methods: This is a single center, population-based cohort study of neonates referred for prenatal exposure to Toxoplasma gondii from January 2014 to December 2020. All infants underwent clinical, laboratory and instrumental investigation for at least 12 months. Results: A total of 670 eligible neonates were referred to the Perinatal Infection Unit of the University Federico II of Naples. Six hundred thirty-six (95%) completed the serological follow up until 12 months. Specific IgG antibodies negativization occurred in 628 (98.7%) within 5 months. At 9 and 12 months, all patients had negative IgG. An initial neonatal IgG antibody titer ≥200 IU/ml was associated with a longer time to negativization (184 [177.5;256] days when above threshold vs. 139.5 [101;179] days when below it; p<0.001). Maternal IgG antibody titer ≥200 IU/ml at childbirth was also associated to delayed time to negativization in the infant (179 [163;184] days above the cut off vs 125 [96.8;178] days below it; p<0.001). Specific antibody negativization was irreversible in all patients. Conclusions: Lower anti-Toxoplasma antibody titers detected at birth in the mother-infant-dyad lead to an earlier and irreversible negativization. This information allows to customize the infant follow up program and avoids invasive and expensive tests.