bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution of cracks in an anchored cavern under blast load based on cohesive elements
Authors: Luo Yi , Pei Chenhao , Qu Dengxing , Li Xinping , Ma Ruiqiu , Gong Hangli 
Published: March 2022

AbstractTo explore the distribution of cracks in anchored caverns under the blast load, cohesive elements with zero thickness were employed to simulate crack propagation through numerical analysis based on a similar model test. Furthermore, the crack propagation process in anchored caverns under top explosion was analyzed. The crack propagation modes and distributions in anchored caverns with different dip angles fractures in the vault were thoroughly discussed. With the propagation of the explosive stress waves, cracks successively occur at the arch foot, the floor of the anchored caverns, and the boundary of the anchored zone of the vault. Tensile cracks are preliminarily found in rocks that surround the caverns. In the scenario of a pre-fabricated fracture in the upper part of the vault, the number of cracks at the boundary of the anchored zone of the vault first decreases then increases with the increasing dip angle of the pre-fabricated fracture. When the dip angle of the pre-fabricated fracture is 45°, the fewest cracks occur at the boundary of the anchored zone. The wing cracks deflected to the vault are formed at the tip of the pre-fabricated fracture, around which are synchronous formed tensile and shear cracks. Under top explosion, the peak displacement and the peak particle velocity in surrounding rocks of anchored caverns both reach their maximum values at the vault, successively followed by the sidewall and the floor. In addition, with the different dip angles of the pre-fabricated fracture, asymmetry could be found between the peak displacement and the peak particle velocity. The vault displacement of anchored caverns is mainly attributed to tensile cracks at the boundary of the anchored zone, which are generated due to the tensile waves reflected from the free face of the vault. When a fracture occurs in the vault, the peak displacement of the vault gradually decreases while the residual displacement increases.
Differences in MS clinical and epidemiological characteristics between Ashkenazi and non-Ashkenazi Jewish patients in Israel: a retrospective single center study
Authors: Karni Arnon , Ben Noon Gil , Shiner Tamara , Vigiser Ifat , Kolb Hadar , Regev Keren 
Published: March 2022

AbstractThe prevalence and severity of Multiple Sclerosis (MS) varies across different ethnicities, with a tendency to a more severe phenotype in non-Caucasian populations. Our objective was to evaluate the differences in disease phenotype between Ashkenazi Jewish and Non-Ashkenazi Jewish patients in Israel. We conducted a single center retrospective cohort study in which subjects were assigned to Ashkenazi or Non-Ashkenazi groups according to self-reported ancestry and disease severity was assessed using the expanded disability status (EDSS), MS severity score (MSSS), progression index (PI) and MRI metrics. 330 Ashkenazi Jewish (AJ) and 207 Non-Ashkenazi Jewish patients (Non-AJ) were included. Non-AJ had a younger age of disease onset (32.7 years vs. 35.7 years, p = 0.05), with a lower proportion of females (62.3% vs. 73.3%, p = 0.01). These differences were maintained within the subgroup of Israeli native patients. Ethnicity was a significant predictor of MSSS (β = 0.601, p = 0.003), with a higher estimate than that of other epidemiological factors. To conclude, Non-AJ patients had an earlier age of onset and a more disabling disease as well as having a more balanced female to male ratio compared to AJ patients. These findings demonstrate variability of disease phenotype within Caucasian patient's dependent on their ethnicity despite equivalent access to healthcare services.
Association between morphine exposure and impaired brain development on term-equivalent age brain magnetic resonance imaging in very preterm infants
Authors: Al-Mouqdad Mountasser M. , Jamjoom Dima Z. , Huseynova Roya , Khalil Thanaa M. , Asfour Yasmeen S. , Albeshri Bushra A. , Basodan Nadia A. , Assiri Fuddah , Asfour Suzan S. 
Published: March 2022

AbstractTo investigate the relationship between morphine exposure in the first week of life and brain injury on term-equivalent age magnetic resonance imaging (MRI) in very preterm infants. A retrospective study included 106 infants with a birth weight of < 1500 g who were born at King Saud Medical City at ≤ 32 gestational weeks, were admitted to the neonatal intensive care unit, and underwent term-equivalent age or pre-discharge brain MRI. A univariate analysis in addition to modified log-Poisson regression with a robust variance estimator was applied, and the effect of early morphine exposure and cumulative dose in the first seven days on brain morphology and growth at term-equivalent age was determined using the Kidokoro score. Sixty-eight (64.2%) infants had received morphine in the first week of life (median cumulative dose: 1.68 mg/kg, interquartile range 0.48–2.52 mg/kg). Early initiation of morphine administration was significantly associated with high total white matter (adjusted relative risk [aRR] 1.32, 95% confidence interval [CI] 1.01–1.72) and cerebellum (aRR 1.36, 95% CI 1.03–1.81) scores and a small cerebellar volume (aRR 1.28, 95% CI 1.02–1.61). Morphine exposure in the first week of life was independently associated with white matter and cerebellar injury on term-equivalent age brain MRI in very preterm infants.
Association of adverse birth outcomes with in vitro fertilization after controlling infertility factors based on a singleton live birth cohort
Authors: Yu Huiting , Liang Zhou , Cai Renzhi , Jin Shan , Xia Tian , Wang Chunfang , Kuang Yanping 
Published: March 2022

AbstractInfants conceived with in vitro fertilization (IVF) are exposed to underlying infertility and the IVF process. High risks of adverse birth outcomes (ABOs) were observed among these infants, including preterm birth, low birth weight, macrosomia, being large/small for gestational age (LGA/SGA). It is unclear whether the specific etiology of the rise of ABOs among IVF infants is IVF technology itself or underlying infertility. A total of 9,480 singletons conceived with IVF and 1,952,419 singletons from the general population were obtained in this study. Multivariable logistic regression model was used to assess variations in risk of ABOs according to causes of infertility. Poisson distributions were applied to calculate standardized risk ratios of IVF infants vs. general population after controlling the causes of infertility. Higher risk of preterm birth and low birth weight were observed among parents with polycystic ovary syndrome, endometriosis, uterine and semen abnormalities. Compared to the general population, after excluding the influence of infertility causes, singletons conceived with IVF were at higher risk of macrosomia (SRR = 1.28, 95% CI 1.14–1.44) and LGA (SRR = 1.25, 95% CI 1.15–1.35). The higher risk of ABOs in IVF was driven by both IVF treatments and infertility, which is important for improving IVF treatments and the managing pregnancies and child development.
Delignification efficiency of various types of biomass using microwave-assisted hydrotropic pretreatment
Authors: Mikulski Dawid , Kłosowski Grzegorz 
Published: March 2022

AbstractThe use of a method of an effective delignification of lignocellulosic biomass is a key stage of designing processes of its microbiological conversion e.g. for the purposes of the production of cellulosic ethanol. The study was aimed at evaluating the effectiveness of microwave-assisted hydrotropic pretreatment using sodium cumene sulfonate (NaCS) for the delignification of pine and beech chips and wheat straw. Research results presenting the impact of process parameters of microwave-assisted hydrotropic delignification confirm a high effectiveness of this method of pretreatment of lignocellulosic biomass. The observed effects included changes in the composition of the biomass and an increased susceptibility of cellulose to the subsequent enzymatic hydrolysis. The use of microwave heating combined with an addition of hydrotrope of 40% w/v NaCS and 117 PSI for 60 min enabled a reduction of the absolute concentration of lignins by 36.58% in pine chips, by 57.68% in beech chips, and by 74.08% in wheat straw. After enzymatic hydrolysis was conducted, the highest concentration of glucose: 463.27 ± 11.25 mg glucose/g (hydrolysis yield 46.76 ± 1.14%) was obtained from the wheat straw, while 327.70 ± 22.15 mg glucose/g (hydrolysis yield 35.13 ± 2.37%) was acquired from the beech chips, and only 50.77 ± 0.75 mg glucose/g (hydrolysis yield 6.63 ± 0.10%) was obtained from the pine chips. Microwave-assisted hydrotropic delignification in the optimum process conditions additionally allows a complete removal of hemicellulose from biomass, which improves the effectiveness of enzymatic hydrolysis. Due to a significant reduction of lignin and hemicellulose concentration in biomass, cellulose—which is susceptible to enzymatic hydrolysis and a source of carbon in biosynthesis processes—becomes the main biomass component.
The beneficial effects of intradialytic parenteral nutrition in hemodialysis patients with protein energy wasting: a prospective randomized controlled trial
Authors: Kittiskulnam Piyawan , Banjongjit Athiphat , Metta Kamonchanok , Tiranathanagul Khajohn , Avihingsanon Yingyos , Praditpornsilpa Kearkiat , Tungsanga Kriang , Eiam-Ong Somchai 
Published: March 2022

AbstractIn hemodialysis (HD) patients, protein-energy wasting (PEW) is highly prevalent and firstly treated with oral nutritional supplements (ONS). The extent to which intradialytic parenteral nutrition (IDPN) contributes to improve PEW status in HD patients intolerable to ONS remains unclear. Maintenance PEW HD patients being unable to tolerate ONS adverse effects, and having spontaneous energy and protein intake of ≥ 20 kcal/kg/day and ≥ 0.8 g/kg/day, respectively were randomly assigned 1:1 into IDPN and control groups. In IDPN group, most concentrated 3-in-1, fish-oil based parenteral nutrition was infused during HD for 3 months. The control group received intensive dietary counselling once weekly for 3 months. Both groups were then followed for additional 3 months after intervention. A total of 38 patients were randomized (mean age 67.6 years). After 3 months, serum albumin was significantly higher in the IDPN (n = 18) compared with control group (from 3.5 ± 0.3 to 3.8 ± 0.2 vs from 3.6 ± 0.3 to 3.5 ± 0.3 g/dL, respectively, p = 0.01). Spontaneous dietary intake (p = 0.04), body weight (p = 0.01), and malnutrition inflammation score (MIS, p = 0.01) were improved in the IDPN, but not in the control group. Muscle mass, strength, serum prealbumin, interleukin-6, high sensitivity-c reactive protein, and acylated ghrelin were not significantly different but leptin levels increased in the control group after 3 months (p = 0.03). At 6 months, serum albumin in the IDPN group was persistently higher than baseline (p = 0.04). Neither volume overload nor uncontrolled hyperglycemia was found throughout the study. In conclusion, a 3-month IDPN supplementation demonstrated a significant increase in serum albumin, body weight, spontaneous oral intake, and MIS; and appeared to be superior to continuing intensive dietary counselling among HD patients intolerable to ONS. The impacts of IDPN therapy on clinical outcomes may require larger scale with longer period of study.
Case study: Co-creating a flipped feed-in approach to a virtual biochemistry lab assessment: increasing student achievement and engagement in a large, diverse cohort
Authors: Cassambai Shabana , Bridge Hannah , Gill Palak K. , Shobaloju Similoluwa , Sgamma Tiziana , Rushworth Jo V. 
Published: March 2022

Abstract
More inclusive, authentic assessments are required to address awarding gaps and to ensure that bioscience students can apply their knowledge to relevant work-based scenarios. In this case report, we present a co-created approach to designing a more inclusive, virtual biochemistry lab assessment for a diverse cohort of ∼270 first-year students. The assignment was to write up an inclusive clinical case study as a one-page journal article. A flipped classroom approach taught the relevant skills, along with simulated labs from Learning Science Ltd. Student Lecturers co-created the assessment, including the marking rubric and the unexemplars. We replaced traditional feedback with a flipped, feed-in approach where students were able to engage in a formative assessment with peer marking and unexemplars. Whilst the summative assessment was marked anonymously, a dialogue-based approach was employed, where students could request personalised audio feed-forward from the tutor. The high pass rate (97%) and student satisfaction score (88%) suggest that this approach is an effective way to challenge, engage and support a large, diverse cohort of students. First-year students who participated in the flipped feed-in experience obtained a significantly higher summative mark (56.7% cf. 50.9%) than those who did not. Interestingly, students in receipt of learning adjustments scored higher marks on average in the summative assessment (59.3% cf. 54.3%), suggesting that we have reversed the disability-based attainment gap. Further investigation into whether a co-created, flipped feed-in approach can reduce attainment gaps based on ethnicity, gender and age is warranted.
Unequal error protection transmission for federated learning
Authors: Zheng Sihui , Chen Xiang 
Published: March 2022

AbstractCommunication has been recognized as one of the primary challenges of federated learning (FL), but the actual communication algorithm or protocol design is still rarely involved in the existing studies. In the paper, viewing the model exchange in FL as a special kind of traffic, an unequal error protection (UEP) scheme is designed based on multi‐rate channel coding and multi‐layer modulation for it. To answer the question of how to make error control for FL when the wireless channel is no longer simplified as a pipeline, this paper firstly theoretically analyzes the impact of transmission error on machine leanring (ML) model, which reveals that the dynamic range of the weights should be taken into consideration. Guided by the analysis, the UEP scheme is applied to FL in multiple perspectives including parameter, network and time. Furthermore, a UEP‐based adaptive coding method is developed for the case with dynamic signal‐to‐noise ratio (SNR) to ensure faster and more stable convergence of the FL model while saving as much bandwidth as possible. Comprehensive numerical simulation on several real‐world datasets verifies that the proposed UEP transmission schemes can indeed bring significant benefits in accuracy, robustness and efficiency, especially when the channel condition is poor.
Calculation, simulation and fast estimation of thermal resistance of rotary voice coil actuators
Authors: Hu Jianhui , Wu Jiaxin , Chen Jinhao , Li Yong , Ren Liuyang , Wang Qian , Liu Chengjun 
Published: March 2022

AbstractRotary voice coil actuator (RVCA) is mainly used for reciprocating drive of small inertia loads in a limited range of angle, which is widely used in aerospace and other fields. Thermal resistance is one of the most important parameters of RVCAs, which is directly related to the steady‐state temperature rising and operation reliability. Because the thermal resistance cannot be measured directly, the analytical method is usually used to calculate the thermal resistance of the RVCA. However, due to the particularity of the thermal circuit calculation, the calculation is complicated and the result is not accurate. It is not conducive for engineering applications of this kind of actuator. In this paper, a series of rotary voice coil motor is selected as the research object. Through analytical calculation and thermal simulation, a more accurate thermal resistance calculation correction model and thermal resistance value of RVCAs are obtained, and the accuracy of the estimation results is verified by experiments. On this basis, the effective volume of the coil frame of the RVCA is selected as the variable, and the concise variation law of the series thermal resistance data is obtained. This paper provides a fast and accurate estimation method for the thermal resistance of RVCA, which has an important reference value for expanding the engineering applications of RVCAs.
An Innovative and Economical Device for Ischemic Preconditioning of the Forehead Flap Prior to Pedicle Division: A Comparative Study
Authors: Xiao Wentian , Ng Sally , Li Hua , Min Peiru , Feng Shaoqing , Su Weijie , Zhang Yixin 
Published: March 2022

Abstract
Background Ischemic preconditioning of the forehead flap prior to pedicle division helps to improve angiogenesis. Clamping the pedicle by a clamped rubber band with vessel forceps is often clinically applied. However, the severe pain and unstable blocking effect influenced the preconditioning process. In this study, we described an innovative device designed for ischemic preconditioning and compared its efficacy with the clamped rubber band.
Methods The device consists of a self-locking nylon cable tie with a buckle and a rubber tube. The rubber tube is fed over the cable tie to act as a soft outer lining and the cable tie is tightened across the pedicle to block the perfusion for ischemic preconditioning. This device and the standard clamped rubber band were applied respectively before division surgery. The constriction effect, reliability, reproducibility, and the patients' pain tolerance were compared.
Results A total of 20 forehead flaps were included. The cable tie had less incidence of loosening (7.7% vs. 16.6%, p < 0.05) and maintained the pressure more effectively. The pain score for the nylon cable tie was significantly lower than the clamped rubber band (4.25 ± 1.02 vs. 6.75 ± 1.12, p < 0.05), especially for 10 pediatric patients (4.50 ± 0.85 vs. 8.10 ± 1.20, p < 0.01). All 20 pedicles were successfully divided at 19 to 22 days with no surgical complications.
Conclusion Compared with the clamped rubber band, the cable tie produces a more reliable and reproducible ischemic preconditioning effect. It is also better tolerated by the patients. Therefore, we recommend using the nylon cable tie as the preferred device for ischemic preconditioning of the forehead flap.
Internal Mammary Lymph Node Biopsy during Microsurgical Breast Reconstruction: A Prospective Study
Authors: Schultz Benjamin D. , Sultan Darren , Ha Grace , Gibstein Alexander , Nguyen Khang , Barnett Sarah L. , Suydam Rebecca C. , Kasabian Armen K. , Smith Mark L. , Tanna Neil 
Published: March 2022

Abstract
Background Accurate assessment of regional lymph node basins is critical for oncological management of breast cancer. The internal mammary lymph node (IMLN) basin directly drains the medial pole of the breast, but biopsy is not commonly performed. While the axillary sentinel lymph node sample remains the standard of care, the majority of patients who have been found to have a positive IMLN biopsy have simultaneously had negative axillary sentinel lymph nodes. This study prospectively examines routine IMLN biopsy during microsurgical breast reconstruction.
Methods An IRB-approved study of routine IMLN biopsies in 270 consecutive patients who underwent microsurgical breast reconstruction was performed from July 1, 2018, to June 1, 2021. Recorded data included unilateral or bilateral breast reconstruction, unilateral or bilateral IMLN sampling, patient demographics, disease stage, and pathologic findings of IMLN.
Results The majority of patients, 240 of 270 patients (88.9%), had bilateral reconstruction. Overall, 5 out of 270 (1.9%) patients had positive IMLN; one of these patients had positive axillary sentinel lymph nodes. The IMLN biopsy results in two of the five patients affected the clinical course as they were upstaged and required chemoradiation.
Conclusion Direct visualization of the internal mammary lymph nodes during dissection of the recipient vessels for microsurgical breast reconstruction allows for convenient sampling, with minimal donor site morbidity and enhances the therapeutic management of patients in whom nodal involvement is present. As such, the authors recommend IMLN sampling.
Collective narratives catalyse cooperation
Authors: Gokhale Chaitanya S. , Bulbulia Joseph , Frean Marcus 
Published: March 2022

AbstractHumans invest in fantastic stories—mythologies. Recent evolutionary theories suggest that cultural selection may favour moralising stories that motivate prosocial behaviours. A key challenge is to explain the emergence of mythologies that lack explicit moral exemplars or directives. Here, we resolve this puzzle with an evolutionary model in which arbitrary mythologies transform a collection of egoistic individuals into a cooperative. We show how these otherwise puzzling amoral, nonsensical, and fictional narratives act as exquisitely functional coordination devices and facilitate the emergence of trust and cooperativeness in both large and small populations. Especially, in small populations, reflecting earlier hunter-gatherers communities, relative to our contemporary community sizes, the model is robust to the cognitive costs in adopting fictions.
The possible modes of microbial reproduction are fundamentally restricted by distribution of mass between parent and offspring
Authors: Pichugin Yuriy , Traulsen Arne 
Published: March 2022

Significance
Cells and simple cell colonies reproduce by fragmenting their bodies into pieces. Produced newborns need to grow before they can reproduce again. How big a cell or a cell colony should grow? How many offspring should be produced? Should they be of equal size or diverse? We show that the simple fact that the immediate mass of offspring cannot exceed the mass of parents restricts possible answers to these questions. For example, our theory states that, when mass is conserved in the course of fragmentation, the evolutionarily optimal reproduction mode is fragmentation into exactly two, typically equal, parts. Our theory also shows conditions which promote evolution of asymmetric division or fragmentation into multiple pieces.
Measurement and suppression of magnetic field noise of trapped ion qubit
Authors: Wei Wenzhe , Hao Peng , Ma Zhiyu , Zhang Huixing , Pang Liren , Wu Fangfei , Deng Ke , Zhang Jie , Lu Zehuang 
Published: March 2022

Abstract
Magnetic field noise is an important factor causing quantum decoherence in quantum systems. In order to suppress the decoherence effect, magnetic field noise needs to be properly measured and controlled. Magnetic field noise power spectrum measurement using a single trapped ion based quantum spectrum analyzer is a very effective way. In this paper, the magnetic field noise measurement based on dynamic decoupling technique is analyzed theoretically. Furthermore, we use magnetically insensitive transition to measure the magnetic field noise, which has the potential to measure stronger magnetic field noise and speed up the measurement process. In our experiment, we suppress the magnetic field noise by using active feedback control and passive compensation, where the required passive compensation amplitude is obtained by measuring the magnetic field noise spectrum of a single 25Mg+ ion. With the magnetic field noise suppressed, the expected contribution of the magnetic field noise to the stability of the 25Mg+–27Al+ ion optical clock can be decreased from

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