bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic Visual Acuity After Small Incision Lenticule Extraction for Myopia Patients
Authors: Wang Yuexin , Guo Yining , Wei Shanshan , Wu Tingyi , Yuan Yifei , Zhang Yu , Li Xuemin , Chen Yueguo 
Published: October 2022

In the present study we compared dynamic visual acuity (DVA) of 84 eyes (for 42 adults with myopia; M age = 28.4, SD = 6.6 years; males = 38.1%, females = 61.9%) at 40 and 80 degree per second (dps) before surgery with eyeglass corrections and after a surgical procedure – a small incision lenticule extraction (SMILE). Participants underwent binocular SMILE surgery with plano refraction targets. Their eyeglass-corrected binocular DVA at 40 and 80 dps was evaluated preoperatively, and their uncorrected binocular DVA was assessed post-operatively at 1 week, 1 month and 3 months. The mean logMAR (logarithm of the minimum angle of resolution) uncorrected and corrected distance visual acuities (UDVA and CDVA) were −0.09 and −0.11 respectively, 3 months postoperatively. The mean preoperative eyeglass-corrected DVAs at 40 and 80 dps were 0.141 and 0.184, respectively, and significant improvements were observed for 40 dps and 80 dps DVAs 3 months postoperatively. Pearson’s correlations were statistically significant between the postoperative DVAs at 3 months and for both the preoperative DVA and postoperative UDVA at both 40 dps and 80 dps. The change in the DVAs at 3 months were significantly associated with the preoperative DVAs at 40 dps and 80 dps. In conclusion, myopic patients’ DVAs significantly improved following SMILE in comparison to corrected preoperative visual acuity when wearing eyeglasses. The post-SMILE DVA was associated with both the preoperative DVA and the postoperative UDVA.
“Why Am I the One Who Gets to Go to Mexico?”: Nepantlera Bridging Among Latinx Students in a Decolonial Study Abroad Program
Authors: Kaneria A. Jyoti , Kasun G. Sue , Marks Beth W. 
Published: October 2022

Background: Little research on Latinx students studying abroad has explored the historic sensibilities they bring to their experiences abroad related to their bordered realities. Research Purpose and Question: This study explores the experiences of Latinx students in one Mexico study abroad class session through the lenses of border theory and Anzaldúan theory. The research question was: What are the experiences of Latinx students as they reflect on their unique participation in a heritage study abroad program, particularly their understanding of the metaphorical “in between” space at borders? Participants: The participants were nine Latinx students. Research Design: The study used a qualitative research design. Findings: Our data analysis revealed two primary findings. First, the students were heavily engaged in nepantla (living in the liminal in-between) as part of the study abroad process. Second, the students experienced connection as nepantleras. The students’ expressions of nepantla were experiences of self-awareness around their guilt and grief. Their nepantlera connection was with themselves; their language, culture, and identity; the group; and their families, in spirit and in the flesh. Conclusions and Recommendations: As the students allowed themselves to talk about, reflect on, and process their feelings, they were planting the seeds for transformation and healing. Because of their facultad (gift of awareness) as nepantleras (bridge builders), we observed the students create bridges not only for their conflicting feelings, but also for their families’ interactions and experiences, all of which were painful and challenging for them. Gaining experiences of connection and strengthening their connectionist facultad provided the students with the opportunity to internalize and embody community building while their facultad gave them an awareness to begin their personal transformations. We argue gaining the lived experience of building community through a connectionist facultad has the potential for the students in this program to create transformative spaces and experiences with their families and their local communities. For K–12 and U.S.-based higher education, our findings support the implementation of ethnic studies and critical multicultural curricula not only to attend to guilt that may be experienced by Latinx youth, but also as a remedy for the disconnect many feel toward their heritage. For directors and researchers of study abroad, we suggest examining both the demographics of the countries where students study and the demographics of the participants in the study abroad group to determine how this influences the students’ feelings and interactions and to guide program development.
Determining massage dose-response to improve cancer-related symptom cluster of pain, fatigue, and sleep disturbance: A 7-arm randomized trial in palliative cancer care
Authors: Miladinia Mojtaba , Jahangiri Mina , Kennedy Ann Blair , Fagerström Cecilia , Tuvesson Hanna , Safavi Shadi Sadat , Maniati Mahmood , Javaherforooshzadeh Fatemeh , Karimpourian Hossein 
Published: October 2022

Background: The efficacy of various massage doses in palliative cancer care settings is still debated, and no specific protocol is available. Aim: Evaluating response to various massage doses for symptom cluster of pain-fatigue-sleep. Design: A 7-arm randomized-controlled trial with weekly massage for 4 weeks depending on the prescribed dose (15-, 30-, or 60-min; 2× or 3×/week) and a 4-week follow-up. The intensities of pain, fatigue, and sleep disturbance were measured using a 0–10 scale at nine-timepoint; baseline, weekly during the intervention, and the follow-up period. Then, the mean scores of the three symptoms were calculated as the symptom cluster intensity at each timepoint. IRCT.ir IRCT20150302021307N5. Setting/participants: Adults with cancer ( n = 273) who reported all three symptoms at three oncology centers in Iran. Results: The odds of clinical improvement (at least 30% reduction in symptom cluster intensity from baseline) increased with dose-escalation significantly [(OR = 17.37; 95% CI = 3.87–77.90 for 60-min doses); (OR = 11.71; 95% CI = 2.60–52.69, for 30-min doses); (OR = 4.36; 95% CI = 0.94–20.32, for 15-min doses)]. The effect durability was significantly shorter at 15-min doses compared to 30- and 60-min doses. The odds of improvement for doses 3×/week was not significant compared to doses 2×/week (OR = 12.27 vs OR = 8.34); however, the effect durability for doses 3×/week was significantly higher. Conclusions: The findings indicated that dose-escalation increases the efficacy of massage for the pain-fatigue-sleep symptom cluster. Although the 60-min doses were found to be more effective, the 30-min doses can be considered more practical because they are less costly and time-consuming. Our findings can be helpful to develop massage guidelines in palliative care settings. Trial registration: Iranian Registry of Clinical Trials, IRCT20150302021307N5.
Dual-energy CT imaging of atherosclerotic plaque using novel ultrasmall superparamagnetic iron oxide in hyperlipidemic rabbits
Authors: Sato Hideyuki , Fujimoto Shinichiro , Kawaguchi Yuko O , Nozaki Yui O , Tomizawa Nobuo , Kogure Yosuke , Minamino Tohru 
Published: October 2022

Background A study using magnetic resonance imaging (MRI) revealed that ultra-small superparamagnetic iron oxide is phagocytosed by macrophages. However, MRI has limitations in obtaining clear images due to its poor spatial and temporal resolutions. Purpose To examine whether the use of dual-energy computed tomography (DECT) facilitated the visualization of carboxymethyl-diethylaminoethyl dextran magnetite ultra-small superparamagnetic iron oxide (CMEADM-U) accumulation in arteriosclerotic lesions using hyperlipidemic rabbits. Material and Methods CMEADM-U at 0.5 mmol Fe/kg was administered to Watanabe hereditary atherosclerotic (WHHL) rabbits (n = 6, 24 sections) and New Zealand white (NZW) rabbits (n = 2, 6 sections). After 72 h, DECT was performed to prepare virtual monochromatic images (35 keV, 70 keV) and an iron-based map. Subsequently, the aorta was collected along with hematoxylin and eosin staining, Berlin blue (BB) staining, and RAM11 immunostaining. Results In the WHHL rabbits, CMEADM-U accumulation was not observed at 70 keV. However, CMEADM-U accumulation consistent with an arteriosclerotic lesion was observed at 35 keV and the iron-based map. On the other hand, in the NZW rabbits, there was no accumulation of CMEADM-U in any images. Further, there were significant differences in the iron-based map value at the site of accumulation among the grades of expression on BB staining and RAM11 immunostaining. In addition, there was a good correlation at 35 kev and iron-based map value (r = 0.42; P < 0.05). Conclusion DECT imaging for CMEADM-U facilitated the assessment of macrophage accumulation in atherosclerotic lesions in an in vivo study using a rabbit model of induced aortic atherosclerosis.
The role of Eustachian tubography and Valsalva CT in Eustachian tube balloon dilation
Authors: Lee Eun Jung , Han Young-Min , Kim Kun Yung 
Published: October 2022

Background Not many imaging techniques have been reported in Eustachian tube imaging. Purpose To investigate the role of selective Eustachian tubography (SET) and Valsalva computed tomography (CT) in patients who underwent Eustachian tube balloon dilation (ETBD). Material and Methods Eligible patients were aged 18 years and older with chronic Eustachian tube dysfunction who had failed medical treatment. On the day of the procedure, Valsalva CT and SET were performed. Participants underwent fluoroscopic ETBD with a 6×20-mm balloon catheter. Clinical examinations to check for the ability to perform the Valsalva maneuver and ETDQ-7 score change were conducted at one week and then at one, two, and six months. Follow-up Valsalva CT was performed in the one-month follow-up. Results A total of 30 ears in 23 patients (16 right ears, 14 left ears; 10 women, 13 men) underwent ETBD from August 2018 to November 2019. Positive CT patency was higher in follow-up Valsalva CT than baseline Valsalva CT (40% and 23.3%, respectively) ( P = 0.006). In SET, positive patency was observed in 13 of 25 ears. Response to balloon dilation was observed in 18 of 25 patients. Clinical success was achieved in 16 of 27 ears. Response to balloon dilation was the only significant predictor of clinical success ( P = 0.012). Conclusion SET depicted the lumen of the Eustachian tube; thereby, it could be a potentially valuable tool in ETBD. Valsalva CT provides additional information about the cartilaginous portion of the Eustachian tube.
Clinical analysis of 78 pulmonary sarcomatoid carcinomas with surgical treatment
Authors: Gong Ting , Jia Bin , Chen Chen , Zhang Zhenfa , Wang Changli 
Published: October 2022

Objective To evaluate clinical factors influencing the postoperative pulmonary sarcomatoid carcinoma (PSCs) prognosis. Methods We retrospectively evaluated patients with PSCs treated from October 2012 to October 2017. Kaplan–Meier survival curves were calculated using univariable analysis (log-rank test). Univariable/multivariable Cox regression analysis was also performed. Results Mixed PSCs were most common (64.10%). Pure PSCs occurred more often with large tumors compared with mixed PSCs. Patients with vs without pleural retraction, respectively, had significantly worse overall survival (OS; 16 vs 23 months) and disease-free survival (DFS; 11 vs 20 months), and patients with airway dissemination had significantly shorter OS (14 vs 21 months) and DFS (11 vs 20 months). Patients with PSC with an adenocarcinoma component had favorable OS. Airway dissemination, pleural retraction, metastatic mediastinal lymph node (LN) number, and pathological tumor-node-metastasis (pTNM) stage were risk factors for short OS. Neither adjuvant chemotherapy nor adjuvant radiotherapy provided a survival advantage. Airway dissemination was an independent prognostic factor (odds ratio, 1.87; 95% confidence interval, 1.04–3.36). Conclusion Pure PSCs were more likely with large tumors compared with mixed PSCs. Airway dissemination, pleural retraction, and metastatic mediastinal LN number were associated with OS. Airway dissemination was an independent prognostic factor.
Prevalences of diabetic foot ulcer and foot self-care practice, and associated factors in adult patients with diabetes in south-east Ethiopia
Authors: Negash Wogene , Assefa Tesfaye , Sahiledengle Biniyam , Tahir Anwar , Regassa Zegeye , Feleke Zegeye , Regasa Tadele , Tekalegn Yohannes , Mamo Ayele , Teferu Zinash , Solomon Damtew , Gezahegn Habtamu , Bekele Kebebe , Zenbaba Demisu , Tasew Alelign , Desta Fikreab , Atlaw Daniel , Wilfong Tara 
Published: October 2022

Objective We aimed to assess the prevalences of foot ulcer and foot self-care practices, and identify associated factors in adult patients with diabetes attending a referral hospital in south-east Ethiopia. Methods We performed a cross-sectional study of 267 diabetic patients. Multivariable binary logistic regression was used to identify factors associated with diabetic foot ulcer and foot self-care practice. Results The prevalence of diabetic foot ulcer was 11.2% (95% confidence interval [CI] 7.42–15.05). One hundred and forty-four (53.9%; 47.9, 59.9) patients demonstrated good foot self-care. Living rurally (adjusted odds ratio 2.27; 95% CI: 1.86–6.97), lack of regular exercise (3.91; 1.51–10.10), peripheral neuropathy (2.77; 1.05–7.33) and foot calluses (5.69; 1.74–18.59) were associated with diabetic foot ulcer. Urban inhabitants (2.01; 1.09–3.69), patients with diabetes for >10 years (2.92; 1.48–5.77), women (2.95; 1.66–5.22), and patients with a glucometer at home (2.05; 1.09–3.85) were more likely to have good foot self-care practice. Conclusion The prevalence of diabetic foot ulcer was 11.2%. This prevalence is lower than those identified in other Ethiopian studies. However, patient awareness regarding foot self-care practice and risk reduction should be improved.
Serum CD14 concentration is associated with obesity and insulin resistance in non-diabetic individuals
Authors: Kang Yea Eun , Joung Kyong Hye , Kim Ji Min , Lee Ju Hee , Kim Hyun Jin , Ku Bon Jeong 
Published: October 2022

Objective CD14 is a lipopolysaccharide-binding protein that serves as a marker of monocytes. The role of circulating CD14 in patients with obesity without diabetes remains unknown. Here, we characterized the relationships between serum CD14 concentration and metabolic parameters related to diabetes and obesity. Methods We performed an observational, prospective case–control study. Eighty participants were evaluated: 26 drug-naïve patients with type 2 diabetes mellitus and 54 healthy individuals. We compared the circulating CD14 concentration and metabolic parameters of the participants with and without diabetes. Results The circulating CD14 concentration did not significantly differ between the two groups, but was lower in participants with obesity than in lean controls. No significant associations existed between CD14 concentration and metabolic parameters in the participants with diabetes, but in those without diabetes, the circulating CD14 concentration significantly negatively correlated with body mass index; waist circumference; the concentrations of fasting insulin, 2-hour post-load glucose, 2-h post-load insulin, and low-density lipoprotein-cholesterol; homeostasis model of assessment (HOMA) of insulin resistance; and HOMA beta-cell function. Conclusions This is the first study to show associations of serum CD14 concentration with metabolic parameters in non-diabetic individuals. Circulating CD14 may represent a useful biomarker of metabolic dysfunction in non-diabetic individuals.
Correlations between serum hepatitis B core-related antigen and hepatitis B surface antigen in patients with hepatitis B cirrhosis and a hepatitis B virus-DNA-negative status: a retrospective study
Authors: Xu Baiguo , Liu Anjing , Liu Ying , Han Tao , Guo Hua , Ding Xian , Xiang Huiling 
Published: October 2022

Objective This study aimed to examine the correlations between serum hepatitis B core-related antigen (HBcrAg) and hepatitis B surface antigen (HBsAg) titers in patients with hepatitis B cirrhosis and a hepatitis B virus (HBV)-DNA-negative status. Methods We retrospectively analyzed the data and blood samples of patients who were diagnosed with HBV liver cirrhosis and an HBV-DNA negative status. These patients were hospitalized between October 2018 and October 2019 at one hospital. Results A total of 180 patients were included. The median (interquartile range) HBsAg and HBcrAg concentrations were 2.77 log10 IU/mL (1.60–3.15) and 3.96 log10 U/mL (2.70–4.97), respectively. A non-linear significant relationship was found between HBsAg and HBcrAg concentrations. The inflection point was 0.58. The effect size and confidence interval on the left and right sides of the inflection point were 0.10 (−0.23–0.42) and 0.62 (0.46–0.78), respectively. When HBsAg concentrations were ≥0.58 log10 IU/mL, HBsAg concentrations were positively correlated with HBcrAg concentrations. When HBsAg concentrations increased by 1 log10 IU/mL, HBcrAg concentrations increased by 0.62 log10 U/mL (95% confidence interval: 0.46, 0.78). Conclusions There might be a non-linear relationship between HBcrAg and HBsAg concentrations in patients with hepatitis B cirrhosis and an HBV-DNA-negative status.
Changes in testicular arterial hemodynamic, gonadotropin levels, and semen parameters among varicocele patients randomized to varicocelectomy or observed in Tamale, Ghana
Authors: Adams Yussif , Amidu Nafiu , Afoko Akisibadek Alekz 
Published: October 2022

Objective: A randomized trial to compared testicular blood flow parameters, gonadal hormones, and semen characteristics among three groups; surgery group ( n = 127); observed group ( n = 114); and healthy controls ( n = 33). Methods: The blood flow parameter selected was resistive index (RI) measured using color Doppler ultrasonography. Serum total testosterone, FSH, LH were measured, and semen analysis performed at baseline and repeated 12 months of follow-up. The data was computed using GraphPad Prism (v8.0) at an alpha of 0.05. Results: In the observed group, increased +0.0060 in the right (R_RI) and in the left (L_RI) +0.0026 capsular arteries from baseline measurement to 12 months follow-up. Surgery group, reduced –0.079 in the right (R_RI) and −0.0731 in the left (L_RI) capsular arteries ( p < 0.0001). At 12 months, the changes for both left and right RIcap in the surgery group did not reach the values of the controls. In the surgery group, L_RIcap ( r = −0.63; p < 0.0001) and R_RIcap ( r = −0.49; p = 0.004) correlated with total testosterone, FSH ( r = 0.57; p = 0.001 for left; r = 0.52; p = 0.002 for right), and LH ( r = 0.61; p = 0.0002 for left; r = 0.41; p = 0.020 for right). Furthermore, L_RIcap correlated with changes in sperm count ( r = −0.46; p = 0.008) and sperm concentration ( r = −0.35; p = 0.011) in the surgery group. Conclusion: Microsurgical sub-inguinal varicocelectomy improves blood supply to the testicular tissues evidenced by reduced resistive index in the surgery group. Resistive index in the left capsular artery can be used to evaluate the success of surgery because it correlates with total testosterone, FSH, LH, and semen quality.
A novel PES-C/(GO-COOH/Ce) blended membrane for treating heavy-metal-ion wastewater
Authors: Zhang Jie , Li Baining , Xue Hongdan , Zhang Chunyan , Li Jinjing , Zhou Shujing 
Published: October 2022

A GO-COOH/Ce complex was introduced into a phenolphthalide polythersulfone (PES-C) matrix to prepare a PES-C/(GO-COOH/Ce) blended membrane by nonsolvent-induced phase transformation (NIPS). FT-IR and EDS analysis confirmed that the GO-COOH/Ce complex was successfully incorporated into the PES-C matrix. SEM showed that the blended membrane possessed an asymmetric structure with finger-like pores. The best comprehensive performance was obtained for a PES-C/(GO-COOH/Ce) blended membrane prepared using 0.1 wt.% of the GO-COOH/Ce complex in the casting liquid. The specific results for the blended membrane were as follows: the fluxes of pure water and 0.1 g/L lead nitrate solution were 272 L/m2·h and 214 L/m2·h, respectively; the rejection of bovine serum albumin (BSA) was 99.4%; the rejection of lead ions was 96.2%; the moisture content was 10.9%; the contact angle was 67.1°; the Young's modulus was 35.7 MPa; and the flux recovery ratio was 1.5 times higher than that of the pure PES-C membrane. The antibacterial-zone diameters of the PES-C/(GO-COOH/Ce) blended membrane used against Escherichia coli and Staphylococcus aureus were 2.50 cm and 2.88 cm, respectively. A catalytic cleaning test showed a flux recovery ratio of 63% after washing the PES-C/(GO-COOH/Ce) blended membrane with a 0.2 g/L acetic acid solution for 0.5 h.
Identifying Priorities and Strategies for Improving Colorectal Cancer Screening in Tribal Clinics
Authors: Blanchard Jessica , Rhoades Dorothy , Nagykaldi Zsolt , Campbell Janis , Cannady Tamela , Hopkins Michelle , Gibson Michelle , Lonewolf Hazel , Doescher Mark 
Published: October 2022

Background Colorectal cancer (CRC) is the 3rd most frequently diagnosed cancer and the 2nd leading cause of cancer death in the United States (US), and incidence and mortality rates in Oklahoma are higher for many American Indian (AI) populations than other populations. The AI CRC Screening Consortium addresses major regional CRC screening disparities among AIs with shared objectives to increase CRC screening delivery and uptake in AIs aged 50 to 75 years at average risk for CRC and to assess the effectiveness of implementations of the interventions. This manuscript reports environmental scan findings related to current practices and multi-stakeholder experiences with CRC screening in two Oklahoma Indian health care systems. Method We conducted a mixed methods environmental scan across five clinical sites and with multiple stakeholders to determine the scope and scale of colorectal cancer screening in two separate AI health care delivery systems in Oklahoma. Data collection consisted of a mixture of individual interviews and group discussions at an urban site, and four clinical care sites within a tribal health system. Results Sixty-two individuals completed interviews. Data from these interviews will inform the development of evidence-based intervention strategies to increase provider delivery, community access to, and community priority for CRC screening in diverse AI health care delivery systems. Conversations with patients, providers, and clinical leadership point to individual and system-level opportunities for improvement at each site, shaped in part by differences in the delivery of services, structure of the health care system, and capacity to implement new intervention strategies. The thematic areas most central to the process of evidenced-based intervention development included: current practices, needs and recommendations, and CRC site priorities. Conclusion Environmental scan data indicated clear opportunities for individual and system-level interventions to enhance CRC screening and was critical for understanding readiness for EBI implementation at each site.