bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of extraction solvents on antioxidant and skin-whitening potentials of defatted Camellia seed cakes
Authors: Kim Jung Hyun , Kim Ji Hye , Kim Min Young 
Published: June 2022

Defatted Camellia japonica L. seed cake is an important byproduct during the manufacture of Camellia seed oil. The present study evaluated the influence of two extraction solvents on the total contents of phenol and flavonoid, antioxidant activity and skin-whitening effect capable of inhibiting the biosynthesis of melanin of defatted Camellia seed cakes, a byproduct from Camellia oil production. The antioxidant capacities of 100% methanol and 70% ethanol extracts were analysed using radical scavenging (1,1-diphenyl-2-picrylhydrazyl, O2-, H2O2 and NO), SOD-like, ferrous ion chelating and reducing power assays. The total phenolic and flavonoid contents were further determined by the Folin-Ciocalteu method. Moreover, intracellular antityrosinase activity and melanin contents were evaluated in human malignant melanoma cells (SK mel-100). Ethanol extracts of defatted Camellia seed cake extracts exhibited higher phenolic (4097 mg gallic acid equivalents/100 g) and flavonoid (2899 mg rutin equivalents/100 g) contents with higher superoxide (IC50 = 1.9 mg/mL), nitric oxide (IC50 =1.6 mg/mL) radical scavenging, ferrous ion chelating (IC50 = 2.9 mg/mL) and reducing power (IC50 = 1.8 mg/mL) activities than those of methanol. These ethanol extracts also evidenced more effective inhibitory activities of tyrosinase and melanin synthesis than methanol extracts. Therefore, the present results demonstrated that defatted Camellia seed cakes could be a valuable source of antioxidative and whitening ingredients, and ethanol was more efficient in extracting antioxidants and bioactive compounds than methanol.
Angiotensin-converting enzyme-2 and interleukin-12 serum level as indicator to severity between COVID-19 patients
Authors: Hasan Huda Khadim , Al-Khafaji Noor Salman Khadim 
Published: June 2022

The Coronavirus, one of the most rapidly spreading respiratory viruses, caused a worldwide epidemic that killed about six million people. This led to the fast development of several vaccines and drugs to reduce disease severity and speed patient recovery. This study aimed to identify the serum levels of each of the angiotensin-converting enzyme-2 and interleukin-12 .The severity of infection in coronavirus COVID-19 patients was compared to immune levels of these cytokines and receptors in the different cases of COVID-19 patients. This case-control study included 90 blood samples from COVID-19 patients with ages between 15-80 years. Results revealed that the serum levels of both angiotensin-converting enzyme-2 ( ACE-2) and interleukin-12 (IL-12) were measured in COVID-19 patients and the results were compared using an independent T-test, it was found that their levels for interleukin-12 revealed a significant difference (P ≤0.05) in the serum levels of severe cases when compared with non-severe cases. There was an increase in the serum level of IL-12 in severe cases was 33.340 ng/L, in the serum level and in non-severe cases was 20.913 ng/L. ( P ≤0.000), and for angiotensin-converting enzyme-2 this study revealed a significant difference in ACE-2 serum levels in severe cases (P ≤0.05) when compared with the non-severe cases of patients with COVID 19. The serum level of ACE-2 in severe cases was 11.023 ng/ml, and in non-severe cases, it was 5.443ng/ml ( P ≤0.000). It was concluded that the emerging coronavirus works to create an immune storm represented by raising the serum levels of both ACE-2 and IL-12 that contribute to the damage to the alveoli in severely COV-19 patients.
Dogielius kaelensis n. sp. (Monogenea, Dactylogyridae), a gill parasite of Garra annandalei Hora, 1921 (Cyprinidae, Labeoninae) in Arunachal Pradesh, India
Authors: Narba Dobiam , Matey Chawan , Tripathi Amit 
Published: June 2022

Parasite biodiversity of fish in Arunachal Pradesh of northeast India is still unexplored. We describe here a new species of Dogielius (Monogenea: Dactylogyridae) from the gill filaments of Garra annandalei(Cyprinidae), collected from the River Kael, Arunachal Pradesh. Dogielius kaelensis n. sp. is distinguished from its congeners by two key features: (i) a robust ventral bar with a medial part twisted forward, and ii) an accessory piece with a ring to help guide the copulatory tube. This is only the second time a member of the genus Dogielius has been found parasitizing a Garra species.
Heavy metals and aluminium intake from stored canned tomato, sardines and tuna in Algeria
Authors: Terbeche Ryme , Samia Gharbi , Rahli Fouzia , Ouadah Karim , Taleb Fawzi , Nassima Draou , Rezini Yacine , Alioua Amel  Berrebbah 
Published: June 2022

This study assessed heavy metals intake and their impacts on healthcare in Algeria. Peculiar attention was given to heavy metals found in largely consumed canned foods in Algeria such as double concentrated tomato, tuna crumbs and sardines. Chemical analyses of the metal and aluminium containers (foil, tray) were performed by X-Ray Fluorescence (XRF) and EDS spectrometry (Energy Dispersive Spectrometry). The determination of the trace metal content in canned food (element metal trace EMT) was achieved by Atomic Absorption Spectrometry (AAS). The approach proposed in this study aimed to highlight the interaction of the product and packaging material, and thus to identify and quantify heavy metals traces that were able to undergo specific or overall migration to food. The morphology of the contact surface food / packaging was observed by Scanning Electron Microscope (SEM) and showed a slight degradation of the base metal (Black Iron). There was an obvious increase in EMTs during tuna, sardines and tomatoes storage and artificial aging. A special interest was given to cooking modes using aluminium foil and trays. ‎‎The respective dosages of aluminium, in baked food (fresh tuna) were obtained. Specific Aluminium migration was noticed and was strong for the flame cooking mode.
Catalytic effect of acetate (C2H3O2) on coulombic efficiency and bio-electricity generation from wastewater sample prepared from domestic kitchen waste using dual chamber microbial fuel cell technology
Authors: Malyan Aarti , Mongia Geeta , Kumar Shani 
Published: June 2022

In recent times, the use of energy resources, particularly non-renewable resources, have increased manifolds due to the ever-increasing global demands. This has led to an increase in depletion of the resources and environmental pollution. Microbial Fuel Cells (MFC) are a new concept that has proved to be the solution to the problem as a green energy resource. The paper focuses on generating electricity from wastewater prepared from kitchen wet waste kept for about 168 hours in an attempt to address the energy crisis while also treating it. A comparative analysis of the sample as prepared and with acetate has been studied and power generation, coulombic efficiency and change in chemical oxygen demand (COD) for wastewater were calculated and also the catalytic effect of acetate was analyzed. It was observed that there was a substantial increase in coulombic efficiency and COD content . A coulombic Efficiency efficiency of 25.29% was obtained for the sample with acetate, whereas, without acetate it was calculated as 9.71%. The maximum power density was obtained from the polarization curves. It was observed that the maximum power density of pure kitchen wastewater was found to be 0.017 mW/m2; however, for kitchen wastewater with acetate, the power density increased considerably to 0.546 mW/m2 at an external resistance of 1Kῼ. Further, the maximum current densities observed were 2.239 mA/m2 and 8.771 mA/m2, respectively. The internal resistance of the constructed prototypes was also determined using the maximum power transfer theorem. In this study, a prototype was constructed and it was found that kitchen waste can be used as a source of electricity generation and leads to a green energy initiative.
Unveiling the structural features of CysE: a novel target for therapeutic interventions against persistent mycobacteria
Authors: Gupta Sunita , Gupta Vibha 
Published: June 2022

World Health Organization (WHO) reports that one-third of the world’s population is infected with a persistent form of Mycobacterium tuberculosis (M.tb), the causative bacterium responsible for causing the dreaded tuberculosis disease. Targeting mycobacterial persisters is important for achieving WHO’s End TB target. The de-novo cysteine biosynthetic pathway is a novel target for addressing M.tb persistence. The two-step pathway comprises of serine acetyltransferase/CysE and O-acetyl-serine-sulfhydrylase/OASS/CysK. The present study is an attempt to understand the structural features of mycobacterial CysE by investigating the divergence amongst orthologous through phylogenetic analysis. Mapping of mycobacterial CysE sequences on the whole orthologous (COG1045) tree segregated the species into four clusters and several isoforms leading to their descendants identification. Interestingly the analysis revealed that the extended C-terminal α-helix believed unique to M.tb is also present in other organisms such as: Campylobacter ureolyticus, Bacillus cereus, Geminocystis herdmanii and Paenibacillus borealis. Further, the Hidden Markov model search against the whole Uniprot database suggests a plausible role of C-terminal α-helix of CysE in strengthening the substrate and/or co-factor binding. In addition, phylogenetic analysis of CysE sequences from the Mycobacteriaceae family facilitates grouping them under ten well-formed and six monophyletic clades, each based on characteristic features with respect to domain architecture, oligomeric assembly, C-terminal tetra-peptide tail, regulatory and feedback mechanism etc. Employing molecular phylogeny in conjunction with structural analysis has provided detailed insights for mycobacterial CysEs as drug target.
Effect of Gallium-68 isotope injection on hemoglobin derivatives concentrations after instant injection and its recovery in male rabbits (Oryctolagus cuniculus)
Authors: Raafat Bassem M. , Osman Hamid , Faizo Nahla L. , Alamri Sultan , Alghamdi Ahmad Joman , Ahmed Rania Mohammed , Almahwasi Ashraf 
Published: June 2022

Oxidizing effects of ionizing radiation are well established and almost understood. However, exposure to low doses of widely used isotopes may result in minor and hidden oxidative stress in some forms of hemoglobin. This formation alteration regarding the legends of hemoglobin's stereochemical function may play a role in hemoglobin dysfunction. There are limited studies related to the effect of gallium isotope injections. The study intends to find the effect of gallium-68 isotope injection on male rabbits. It was conducted on thirty-two male rabbits (Orycytolagus cuniculus) divided into Group I: control and Group II: animals exposed to gallium-68 isotope at a similar dose commonly used in diagnostic protocols for humans. Blood samples were collected twice: the first was after two hours of injection with isotopes and the second was after twelve hours of injection. A linear, four-mathematical-equations matrix based on the Lamber-Beer law was used to measure the concentration of different hemoglobin derivatives. Results revealed a significant elevation (P<0.05) of methemoglobin, the oxidized form of hemoglobin, two hours after injection (Total hemoglobin = 4.463 ± 0.83), but this effect was completely reversed after twelve hours. This concluded that even low doses of isotopes result in oxidation of hemoglobin that recovers shortly. Furthermore, the outcome of the study supports the healthcare centres to understand the effect of gallium-68 injections on animals.
Physicochemical, antioxidant and antimicrobial properties of citrus peel essential oils
Authors: T. Aruna , G. Hemalatha , K. Kumutha , S. Kanchana , S. Vellaikumar 
Published: June 2022

Essential oils are produced as secondary metabolites of aromatic plants and can be extracted from leaves, seeds or fruit peel of the plants. Citrus peel is a rich source of limonene which is antimicrobial in nature. The present study aimed to deal with the physicochemical, antioxidant and antimicrobial properties of citrus peel essential oil from Citrus reticulate (mandarin orange), Citrus limetta (mosambi) and Citrus limon (lemon). The lemon peel oil had lower peroxide value (1.6 meq/kg of sample), saponification value (112.2 mg KOH/g of oil) and higher iodine value (116 gI2/100g oil) when compared with orange and mosambi peel essential oil. DPPH (2,2-diphenyl-1-picrylhydrazyl) free radical scavenging activity of citrus peel essential oil was measured and the result indicated that the total antioxidant activity of lemon peel oil was 89.2 % Radical Scavenging activity (RSA). The antifungal activity was assessed by agar dilution method, whereas the antibacterial property was assessed by the agar diffusion method. Lemon peel oil recorded better antimicrobial properties with minimum inhibitory concentration of 0.3% against Aspergillus flavus MTCC 277, 0.2% for Penicillium MTCC 1995 and Fusarium oxysporum MTCC 284. Likewise, the minimum inhibitory concentration of lemon peel oil against Staphylococcus aureus MTCC 96 was 0.3%; Salmonella enterica MTCC 733 and Erwinia sp MTCC 2760 was 0.5%; Pseudomonas aeruginosa MTCC 1688 and Escherichia coli MTCC 443 was 0.7%. This comparative study showed that lemon peel oil had better physicochemical and antioxidant property. Lemon peel oil can be used as a preservative in the food system as it exhibited antibacterial and antifungal activity.
Використання нових інформаційних технологій у викладанні психологічних дисциплін майбутнім педагогам
Authors: Пилипенко К.В. 
Published: June 2022

XXI століття - це епоха змін, інновацій, інтелекту, глобалізації, яка вимагає оволодіти ключовими компетентностями в інтелектуальній, правовій, комунікаційній, інформаційній сферах, змінює суму знань, необхідних сучасній людині та способи вивчення нового, докорінно змінює політику в області науки і освіти, формує багатофункціональні, надпредметні, базові компетентності. Інформаційні технології набувають усе більшого поширення в різних сферах освітньої та професійної діяльності. Їхні невичерпні можливості, розвиток компютерних систем звязку сприяють формуванню інформаційного суспільства й висувають нові вимоги до освіти молодого покоління. Підготовка студентів педагогічних вишів повинна відбуватися з рахуванням досягнень і перспектив розвитку техніки й технології. Удосконалення рівня технологічної діяльності майбутніх педагогів з використанням інноваційних методів навчання закладає фундамент самоосвіти і саморозвитку. Використання комп'ютера як інформаційного, навчального та контролюючого технічного засобу сприяє вдосконаленню традиційних методик вивчення спеціальних дисциплін.
İbrâhim (a.s) ve Ailesinin Urfa ile Olan Bağlantısı
Authors: GÜNDÜZ Ahmet 
Published: June 2022

Urfa’nın dinî anlamda en kabul görmüş niteliği “Peygamberler Şehri” oluşudur. Peygamberler içerisinde kendisiyle en fazla özdeşleştirildiği peygamber ise Hz. İbrâhim’dir. Urfa bölgesinin Hz. İbrâhim’in (a.s.) ailesi özelindeki bağlantısının ilmî verilere dayalı olarak ortaya konması büyük önem arz etmektedir. Böyle bir çalışma halk arasındaki inanışın ve seyyahların notlarında yer alan bilgilerin ne denli doğru olduğunu da ortaya çıkacaktır.
Kur’an’da Hz. İbrâhim’in ailesi bağlamında Urfa bölgesine dair açık bir isim geçmemektedir. Ancak Tevrat ve İncil’de bazı ayrıntılar yer almaktadır. Bu bilgiler arkeolojik veriler, tarihî bilgiler ve ilmî disiplinler göz önüne alınarak yorumlandığında konu açığa kavuşmaktadır. Buna göre Hz. İbrâhim’in ve ailesinin Urfa, Harran, Suruç ve eskiden Harran’a bağlı olan ‘Aynu’l-‘Arûs arasında son derece yakın bir ilişkisi vardır. Babası, amcaları ve dayıları bu bölgede yaşamıştır. Hz. İbrâhim’in doğumu, ateşe atılması ve ilk evliliği buralarda olmuş, hicreti de bu bölgeden başlamıştır. Oğlu İshâk ve torunu Ya‘kûb’un bölge ile bağı sıhriyet yoluyla devam etmiştir.
Psikolojik Savaş ve İslam’ın İlk Döneminde Bazı Uygulamaları
Authors: ERBİL Kadir 
Published: June 2022

Soğuk savaşın bir türü olan psikolojik savaş, tarih boyunca hayatın her alanında farklı amaçlar için uygulanmıştır. Psikolojik savaşın bir yöntemi olan propaganda ise hedef kitleye karşı uygulanan bir iletişim şeklidir. Propaganda, özellikle savaş esnasında olayları çarpıtarak hedef kitleyi aldatmak için kullanılır. Psikolojik savaş ve propagandanın sosyolojik bir bakışla ele alınması, önemli bir araştırma konusudur. Bu bağlamda söylenti/dedikodu da hedef kitleyi yıpratmak için kullanılan bir taktiktir. İçeriği yanlış veya asılsız olsa bile söylenti/dedikodu toplumu etkileyerek insanları şüpheye düşüren, morallerini bozarak şevklerini kıran bir metottur.
Konu ile yakından ilgili olması nedeniyle çalışmamızda öncelikle psikolojik savaş, propaganda ve algı üzerinde durulmuştur. İslam’da psikolojik savaştan sonra Hz. Peygamber’e karşı uygulanan psikolojik savaşa değinilmiştir. Mekke müşriklerinin uyguladıkları kara propaganda ve psikolojik savaş üzerinde durularak gerekli yorumlar yapılmıştır. Çalışmanın konusu Mekke dönemi ile sınırlandırılmıştır.
Analisis Penerapan Prinsip–prinsip Good Corporate Governance Pada Usaha Kecil dan Menengah (Studi Pada UKM Restoran/Rumah Makan/Kafe di Daerah Cikupa Tangerang)
Authors: Febianty Febianty 
Published: June 2022

Berbagai trend baru dalam lingkungan manufaktur membawa dampak terhadap kualitas. Untuk dapat menghasilkan suatu produk yang berkualitas, maka perusahaan harus memperhatikan berbagai aspek seperti bahan baku, biaya produksi yang dikeluarkan, sumber daya perusahaan, serta manajemen kualitas produk tersebut. Mengetahui pengaruh total quality management (TQM) terhadap kualitas produk yang dihasilkan dan mengetahui hubungan antara efisiensi biaya produksi terhadap peningkatan kualitas produk yang dihasilkan. Dilakukan penelitian deskriptif analitis dengan menggambarkan data yang diperoleh dan menganalisis data yang ada. Penelitian ini dilakukan dengan studi kasus untuk melakukan penelitian lebih mendalam sehingga dapat memberikan gambaran yang jelas dan lengkap. Melalui penerapan TQM, PT Busana Ragi Inovasi pada tahun 2017 mampu mengurangi produk cacat sebesar 23,55%, meningkatkan volume produksi sebesar 12,17%, efisiensi biaya produksi sebesar 1,49%. Oleh karena itu, PT Busana Ragi Inovasi mampu meningkatkan penjualan bersih sebesar 8,58% dan meningkatkan laba perusahaan sebesar 2,69% dari tahun 2016. Penerapan TQM dan efisiensi biaya produksi pada PT Busana Ragi Inovasi mampu menunjukan bahwa perusahaan tetap dapat menghasilkan kualitas produk yang baik
Development of methods for quantification of gelatin in vegetable capsule shell and for classification of capsule shell as from vegetable or animal sources by chemometric analysis of FTIR spectroscopic data
Authors: Debnath A , Uddin MN , Jahan RA , Rana AA , Karim MM 
Published: June 2022

Capsule shell from animal source (bovine or porcine gelatin) is a problem for the follower of different religions and vegetarian. In that case, vegetable capsule shell could be a solution. In this research, we proposed a simple and cost-effective technique for detection of gelatin in vegetable capsule shell and for classification of capsule shell by source, based on Chemometric techniques with FTIR spectroscopic data. Partial Least-Square Regression (PLSR) models were developed and their efficiencies were assessed with spectroscopic data of range of 4000-700 cm-1. PLSR shows very good prediction efficiency (R2= 98%) for both vegetable capsule shell and gelatin. In addition, Soft Independent Modeling by Class Analogy (SIMCA) classification method were developed and assessed with spectral data of capsule shells from vegetable and animal sources. Results prove that FTIR spectroscopy in combination with chemometric method can be used for the classification of capsule shell by source and quantification of gelatin in vegetable capsule shell to ensure their authenticity.
Bangladesh J. Sci. Ind. Res. 57(2), 91-98, 2022
Mononuclear cobalt(III) azido complex containing a tetradentate amine: one pot synthesis, structure and thermal behavior
Authors: Khan Sumitava 
Published: June 2022

One hexacoordinated mononuclear complex trans-[Co(L)(N3)2] PF6 (1) [L = N,N′-bis(3-aminopropyl)- 1,2-ethanediamine] is prepared by using one-pot reactions of the building units and characterized. X-ray analysis shows that cobalt center in 1 adopts a distorted octahedral geometry with CoN6 chromophore ligated through four N atoms of tetradentate amine (L) and the two N atoms of terminal azides in mutual trans orientation. In the crystalline state, double N-H…N and multiple N-H…F hydrogen bondings result in 2D sheet structure. The compound has a thermal stability up to 193°C.
Bangladesh J. Sci. Ind. Res. 57(2), 109-116, 2022
ANALISIS PENGEMBANGAN WISATA ALAM AIR TERJUN WIDURI SEBAGAI KAWASAN EKOLOGI PARIWISATA
Authors: Nasikhah Lailiyatun , Fikri Achmad Ali 
Published: June 2022

Widuri Waterfall has its own uniqueness compared to other tourist attractions in Grobogan. The natural nature of the Widuri Waterfall is the main attraction for visitors. This study aims to explore how the development of ecotourism in the Widuri waterfall area has applied the principles of ecotourism or not. This research is included in the field research, with a qualitative approach and descriptive analysis. Data collection techniques in the form of interviews, observation and literature study. Based on the research that has been carried out, it is found that in tourism development every year holding environmental conservation activities, every tree around the tourism is given a name and its benefits, then tourism development has also involved the role of the local community. It can be concluded that the development of Widuri waterfall tourism has met the requirements of the principles of eco-friendly tourism development, namely the existence of the principle of conservation, the principle of education, the principle of tourism, the principle of economics and the principle of community participation. Researchers suggest to managers to continue to evaluate continuously in the development of ecotourism Widuri waterfall so as not to disturb and damage the function of the natural environment around the Widuri waterfall area. With this research, it is hoped that tourism managers will continue to pay attention to the principles of tourism development based on the principles of ecological development. Keywords: Development, Ecotourism, Waterfall
KEANEKARAGAMAN INSEKTA (ORDO LEPIDOPTERA) DI PUSAT SUAKA SATWA ELANG JAWA BOGOR
Authors: Krismawanti Rizky , Rostikawati Teti , Prasaja Dimas 
Published: June 2022

The Javan Eagle Wildlife Sanctuary Center (PSSEJ) is one of the regions in Indonesia that has a high diversity of flora and fauna in Bogor, West Java. One of the fauna that live in PSSEJ is an insect of the order Lepidoptera. The limited information about Lepidoptera in this location causes the data on the diversity of these species to not be known with certainty. It is necessary to research the diversity of Lepidoptera. This study aims to study the species diversity of the order Lepidoptera at the Javan Eagle Wildlife Sanctuary Center. This research is an exploratory research conducted from December 2020 to August 2021 in two routes, namely track 1 (camping ground area) and route 2 (officer entrance route and land use). The research method uses a survey method using a sweeping net technique. Collecting data in the form of primary data covering the number of Lepidoptera species and secondary data covering temperature, humidity and light intensity. Based on the research, it was found 39 species of the order Lepidoptera with a moderate diversity index of 2.84, a high evenness index of 0.87 and a low dominance index of 0.08. Keywords: Diversity, Javan Eagle Sanctuary Center, Lepidoptera