bluuebunny/crossref_metadata_2025_split huggingface dataset:
Primäre Angiitis des Zentralnervensystems
Authors: Gattringer Thomas , Seifert-Held Thomas 
Published: June 2022

ZusammenfassungDie primäre Angiitis des Zentralnervensystems ist eine sehr seltene Erkrankung, welche durch eine entzündliche Infiltration der Gefäßwände von mittleren und kleinen Gefäßen ausschließlich im Zentralnervensystem, vorwiegend im Gehirn, gekennzeichnet ist. Klinisch und radiologisch kann sich die Erkrankung äußerst vielgestaltig präsentieren und stellt daher eine besondere diagnostische Herausforderung dar. Die häufigsten klinischen Manifestationen sind subakut auftretende Kopfschmerzen, enzephalopathische Zustandsbilder oder schlaganfallähnliche Episoden bei Auftreten von akuten zerebralen Ischämien oder Blutungen. Eine umfassende differenzialdiagnostische Abklärung ist nötig. Neben einer sorgfältigen Anamnese und klinischen Untersuchung stellen die zerebrale MRT, Lumbalpunktion, digitale Subtraktionsangiographie sowie weiterführend die Hirnbiopsie wichtige diagnostische Modalitäten dar. Vor Einleitung der notwendigen immunsuppressiven Therapie, welche zumeist aus Kortikosteroiden und Cyclophosphamid besteht, sollte eine histopathologische Diagnosesicherung erfolgen. Aufgrund der Seltenheit und Komplexität der Erkrankung und des individuellen Therapie- und Nachsorgekonzeptes soll die Betreuung (inkl. regelmäßigen klinischen Kontrollen) von PatientInnen mit primärer Angiitis des Zentralnervensystems an einem Zentrum mit entsprechender Erfahrung und Expertise erfolgen.
The fiscal consequences of immigration: a study of local governments’ expenditures
Authors: Viren Matti 
Published: June 2022

AbstractIn this paper we examine how Finnish municipalities’ expenditures depend on the share of citizens with foreign background out of the total population. Empirical analyses make use of Finnish panel data from 295 municipalities and 202 migrant nationalities for the period 1987–2018. It turns out that the share of foreign population tends to increase per capita expenditures up to the point where the respective semi-elasticity is about one. The result seems robust in terms of different control variables, subsamples of the data and estimation techniques. Sizeable differences between different nationalities could, however, be detected. Thus, we cannot assume that the use of public services is neutral in terms of demographic changes and that should be considered when making assessments on overall fiscal effects of migration.
Parkinsonism in idiopathic normal pressure hydrocephalus: is it time for defining a clinical tetrad?
Authors: Mostile Giovanni , Fasano Alfonso , Zappia Mario 
Published: June 2022

Abstract
Background
Association between parkinsonism and idiopathic normal pressure hydrocephalus (iNPH) still remains debated. There is already plenty of evidences in the literature suggesting that this clinical sign can be considered as an integral part of the clinical spectrum of iNPH patients.

Methods
We reviewed the possible pitfalls in the core clinical definition of iNPH based on available international diagnostic criteria, phenomenology of parkinsonism in iNPH, and neuroimaging supporting the presence of parkinsonism in iNPH.

Conclusions
We argue that the diagnostic definition of the iNPH “triad” should be possibly reconsidered as a “tetrad” also including parkinsonism.
A qualitative analysis of facilitators and barriers to physical activity among patients with moderate mental disorders
Authors: van Rijen Denise , ten Hoor Gill A. 
Published: June 2022

Abstract
Aim
The current study aims to qualitatively identify determinants, barriers and facilitators of physical activity among a population with mental health disorders.

Subject and methods
Seventeen participants with moderate mental disorders were recruited. Semi-structured interviews were conducted to identify physical activity facilitators and barriers. Data were organized and analysed in ATLAS.ti, mainly based on a generic qualitative research approach.

Results
Most participants found physical activity important and expressed a positive attitude towards it. In general, higher self-efficacy and more social support were beneficial for participants’ physical activity levels. Reasons/facilitating factors to be more physically active were: having fun, good weather, progress, routine, self-compassion and a stimulating environment. Barriers were not having fun, being busy, mental complaints, lack of energy, procrastination and physical complaints.

Conclusion
Future interventions could promote physical activity among people with moderate mental disorders to help them identify and overcome barriers. The newly identified determinant ‘self-compassion’ could be an interesting target for promoting physical activity in this group of people with moderate mental disorders.
Using the Dafermos entropy rate criterion in numerical schemes
Authors: Klein Simon-Christian 
Published: June 2022

AbstractThe following work concerns the construction of an entropy dissipative finite volume solver based on the convex combination of an entropy conservative and an entropy dissipative flux. We aim to construct a semidiscrete scheme that is entropy stable in the sense of the entropy criterion of Dafermos as well as in the classical sense entropy dissipative. The proposed semidiscrete scheme shows nice properties like 2porder accuracy in smooth regions as well as a non-oscillatory behavior around shocks.
Conditioning geological surfaces to horizontal wells
Authors: Vázquez Ariel Almendral , Dahle Pål , Abrahamsen Petter , Sektnan Audun 
Published: June 2022

AbstractKriging is a standard method for conditioning surfaces to observations. Kriging works for vertical wells, but may produce surfaces that cross horizontal wells between surface observations. We establish an approach that also works for horizontal wells, where surfaces are modeled as a set of correlated Gaussian random fields. The constraints imposed by the horizontal wells makes the conditional surfaces non-Gaussian. We present a method for exact conditional simulation and an approximation for prediction and prediction uncertainty. Thousands of constraints can be handled efficiently without numerical instabilities. The approach is illustrated with synthetic and real examples that show how the constraints influence the surfaces and reduce uncertainty.
A collection of Constraint Programming models for the three-dimensional stable matching problem with cyclic preferences
Authors: Cseh Ágnes , Escamocher Guillaume , Genç Begüm , Quesada Luis 
Published: June 2022

AbstractWe introduce five constraint models for the 3-dimensional stable matching problem with cyclic preferences and study their relative performances under diverse configurations. While several constraint models have been proposed for variants of the two-dimensional stable matching problem, we are the first to present constraint models for a higher number of dimensions. We show for all five models how to capture two different stability notions, namely weak and strong stability. Additionally, we translate some well-known fairness notions (i.e. sex-equal, minimum regret, egalitarian) into 3-dimensional matchings, and present how to capture them in each model. Our tests cover dozens of problem sizes and four different instance generation methods. We explore two levels of commitment in our models: one where we have an individual variable for each agent (individual commitment), and another one where the determination of a variable involves pairing the three agents at once (group commitment). Our experiments show that the suitability of the commitment depends on the type of stability we are dealing with, and that the choice of the search heuristic can help improve performance. Our experiments not only brought light to the role that learning and restarts can play in solving this kind of problems, but also allowed us to discover that in some cases combining strong and weak stability leads to reduced runtimes for the latter.
Epigenetic effects associated with salmonid supplementation and domestication
Authors: Koch Ilana J. , Nuetzel Hayley M. , Narum Shawn R. 
Published: June 2022

AbstractSeveral studies have demonstrated lower fitness of salmonids born and reared in a hatchery setting compared to those born in nature, yet broad-scale genome-wide genetic differences between hatchery-origin and natural-origin fish have remained largely undetected. Recent research efforts have focused on using epigenetic tools to explore the role of heritable changes outside of genetic variation in response to hatchery rearing. We synthesized the results from salmonid studies that have directly compared methylation differences between hatchery-origin and natural-origin fish. Overall, the majority of studies found substantial differences in methylation patterns and overlap in functional genomic regions between hatchery-origin and natural-origin fish which have been replicated in parallel across geographical locations. Epigenetic differences were consistently found in the sperm of hatchery-origin versus natural-origin fish along with evidence for maternal effects, providing a potential source of multigenerational transmission. While there were clear epigenetic differences in gametic lines between hatchery-origin and natural-origin fish, only a limited number explored the potential mechanisms explaining these differences. We outline opportunities for epigenetics to inform salmonid breeding and rearing practices and to mitigate for fitness differences between hatchery-origin and natural-origin fish. We then provide possible explanations and avenues of future epigenetics research in salmonid supplementation programs, including: 1) further exploration of the factors in early development shaping epigenetic differences, 2) understanding the functional genomic changes that are occurring in response to epigenetic changes, 3) elucidating the relationship between epigenetics, phenotypic variation, and fitness, and 4) determining heritability of epigenetic marks along with persistence of marks across generations.
Too Many Males or Too Many Females? Classroom Sex Ratio, Life History Strategies and Risk-Taking Behaviors
Authors: Salas-Rodríguez Javier , Gómez-Jacinto Luis , Hombrados-Mendieta Isabel , del Pino-Brunet Natalia 
Published: June 2022

AbstractPrior research finds that sex ratio, defined as the proportion of males and females in a given context, is related to engagement in risk-taking behaviors. However, most research operationalizes sex ratio at a local context (e.g., regional or county), which fails to reflect with precision the sex ratios contexts of individuals at a closer level. Furthermore, the relationship between sex ratio and risk-taking behaviors may be affected by individuals’ life history strategy, with previous studies showing fast life history strategies linked to risk-taking behaviors, compared to slow life history strategies. The present study analyzes the relationship between classroom sex ratio and risk-taking behaviors and the interaction between classroom sex ratio and life history strategy in adolescents. The sample comprised 1214 participants nested in 57 classrooms, 49.75% females, 91.5% Spanish and a mean age of 16.15 years (SD = 1.23, range 14–21). Results from multilevel modeling showed a negative relation between classroom sex ratio and risk-taking behaviors in female adolescents with faster life history strategy. By contrast, classroom sex ratio in male adolescents related positively to risk-taking behaviors but did not interact with life history strategy. These findings underscore the importance of studying proximate sex ratio on risk-taking behaviors in adolescents and underline its potential influence in the development and expression of life history strategies.
Moderate heat stress prevented the observed biomass and yield stimulation caused by elevated CO2 in two well-watered wheat cultivars
Authors: Chavan Sachin G. , Duursma Remko A. , Tausz Michael , Ghannoum Oula 
Published: June 2022

Abstract
Key message
Heat stress (HS) under well-watered conditions was not detrimental to leaf photosynthesis or yield but modified the elevated CO2 response of photosynthesis and yield in two contrasting wheat cultivars.

Abstract
Climate change is increasing the frequency of extreme events such as heat waves, adversely affecting crop productivity. While positive impacts of elevated carbon dioxide (eCO2) on crop productivity are evident, the interactive effects of eCO2 and environmental stresses are still unclear. To investigate the interactive effects of elevated CO2 and heat stress (HS), we grew two contrasting wheat cultivars, early-maturing Scout and high-tillering Yitpi, under non-limiting water and nutrients at ambient (aCO2, 450 ppm) or elevated (eCO2, 650 ppm) CO2 and 22 °C in the glasshouse. Plants were exposed to two 3-day HS cycles at the vegetative (38.1 °C) and/or flowering (33.5 °C) stage. At aCO2, both wheat cultivars showed similar responses of photosynthesis and mesophyll conductance to temperature and produced similar grain yield. Relative to aCO2, eCO2 enhanced photosynthesis rate and reduced stomatal conductance and maximal carboxylation rate (Vcmax). During HS, high temperature stimulated photosynthesis at eCO2 in both cultivars, while eCO2 stimulated photosynthesis in Scout. Electron transport rate (Jmax) was unaffected by any treatment. eCO2 equally enhanced biomass and grain yield of both cultivars in control, but not HS, plants. HS reduced biomass and yield of Scout at eCO2. Yitpi, the cultivar with higher grain nitrogen, underwent a trade-off between grain yield and nitrogen. In conclusion, eCO2 improved photosynthesis of control and HS wheat, and improved biomass and grain yield of control plants only. Under well-watered conditions, HS was not detrimental to photosynthesis or growth but precluded a yield response to eCO2.
Measurements of Laminar Burning Velocities of Alternative Fuels: Application in Transport and Aerospace
Authors: Richter Sandra , Braun-Unkhoff Marina , Naumann Clemens 
Published: June 2022

AbstractThe laminar burning velocity belongs to the fundamental combustion properties of fuels being a measure for their heat release, flame length, as well as reactivity and combustion stability, and thus, may impact the design of burners and combustion chambers. Also, these experimental data are needed for the validation and optimization within the construction and development of detailed chemical kinetic reaction mechanisms. Within this study, an overview of the different applications of fuel characterization regarding the specific area of interest (road transport, aviation, and aerospace) will be given. Depending on the application, effects of different molecular characteristics on the laminar burning velocity are evaluated: the presence of oxygen atoms and the grade of branching in a specific fuel molecule as well as the difference in the type of a chemical bond, here, single and double bonds. Examples of alternative fuels being discussed in the present study are: (I) oxymethylene ether (OMEn) in the field of road transport; (II) a paraffinic Alcohol-to-Jet fuel as sustainable aviation fuel; and (III) mixtures of ethane or ethene with nitrous oxide as green propellants for rocket propulsion applications.
The key to happiness in collaborative workplaces. Evidence from coworking spaces
Authors: Berdicchia Domenico , Fortezza Fulvio , Masino Giovanni 
Published: June 2022

AbstractThis quantitative study explores the significant psychological and behavioral dynamics in coworking spaces. We collected data from a sample of 175 people working in Italian coworking spaces and found that a more cooperative organizational climate increases coworking space users’ happiness. We also found that this relationship is positively moderated by several job crafting behaviors. More specifically, when workers are proactive in the work environment, they are more likely to benefit from the potential advantages (resources, challenges, networking opportunities, etc.) that cooperation-oriented work settings provide, which, in turn, amplifies the positive effect of cooperative work settings on individual happiness. These findings make a useful contribution to both the growing literature on coworking spaces and the more general job crafting literature. Indeed, the previous research on both behavioral dynamics that are specific to coworking spaces and on the role played by job crafting in influencing workers’ happiness remains limited. The study’s managerial implications concern the relevance of establishing a cooperative climate and encouraging workers’ proactivity to promote their happiness.
Antagonists of the Mu-Opioid Receptor in the Cancer Patient: Fact or Fiction?
Authors: Belltall Amparo , Mazzinari Guido , Diaz-Cambronero Oscar , Eroles Pilar , Argente Navarro María Pilar 
Published: June 2022

Abstract
Purpose of Review
Antagonists of mu-opioid receptor role in cancer progression remains to be elucidated. The objective of this review was to summarize the available evidence on antagonists of mu-opioid receptor effect on tumor progression and prognosis in different types of cancers and an evaluation of the available findings on their mechanism of action.

Recent Findings
We have found studies related to methylnaltrexone (MNTX) and naltrexone (NTX) usage in cancer outcomes-related setting. We found consistent preclinical evidence of a potential action of MNTX and NTX on cancer growth and spread mediated mainly by effect on the opioid growth factor receptor (OGFr) axis, which results in depressed cell replication. However, clinical results are scarce and limited to poor-quality evidence.

Summary
Further high-quality studies are warranted to study antagonists of mu-opioid receptor role as a therapeutic option in different types of cancer, especially in patients where the classical treatment causes unacceptable side effects.
On critical double phase Kirchhoff problems with singular nonlinearity
Authors: Arora Rakesh , Fiscella Alessio , Mukherjee Tuhina , Winkert Patrick 
Published: June 2022

AbstractThe paper deals with the following double phase problem $$\begin{aligned} \begin{aligned}&-m \left[ \int _\Omega \left( \frac{|\nabla u|^p}{p} + a(x) \frac{|\nabla u|^q}{q}\right) \,\mathrm {d}x\right] {\text{div}} \left( |\nabla u|^{p-2}\nabla u + a(x) |\nabla u|^{q-2}\nabla u \right) \\&\quad = \lambda u^{-\gamma } +u^{p^*-1}&\quad \text {in } \Omega ,\\&u > 0&\quad \text {in } \Omega ,\\&u = 0&\quad \text {on } \partial \Omega , \end{aligned} \end{aligned}$$

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Polystyrene shaping effect on the enriched bacterial community from the plastic-eating Alphitobius diaperinus (Insecta: Coleoptera)
Authors: Cucini Claudio , Funari Rebecca , Mercati David , Nardi Francesco , Carapelli Antonio , Marri Laura 
Published: June 2022

AbstractPlastic pollution has become a serious issue of global concern, and biodegradation of plastic wastes is representing one attractive environment-friendly alternative to traditional disposal paths. It is known that insects are involved in the plastic polymer degradation process, with reported evidence of tenebrionid beetle larvae capable to degrade polystyrene (PS), one of the most used plastics worldwide. Recently, a ribosomal RNA based survey on the insect gut microbiota of the lesser mealworm Alphitobius diaperinus has revealed differentially abundant microbial taxa between PS-fed larvae and control group. Following these findings, an enrichment bacterial culture was set up in liquid carbon-free basal medium with PS film as sole carbon source using PS-fed larvae of A. diaperinus as inoculum. After two-months the culture was analysed both by molecular and culture-based methods. Isolated bacteria which had become prevalent under the selective enrichment conditions resulted ascribable to three taxonomic groups: Klebsiella, Pseudomonas, and Stenothrophomonas. The predominance of these groups in PS-fed larvae was confirmed by using bacterial 16S rRNA gene amplicon sequencing, and it was consistent with the results of previous reports. Isolated bacteria were able to attach to PS surfaces and SEM observations showed the presence of thin fibrillar structures connecting the bacterial cells to the abiotic surface.
Possibilities and problems of using drama to engage with First Nations content and concepts in education: A systematic review
Authors: Hradsky Danielle , Forgasz Rachel 
Published: June 2022

AbstractEducators around the world are increasingly considering and seeking ways to challenge their role in the colonial project. Some have turned to embodied pedagogies as a way to encourage holistic, relationships-based learning in academies which traditionally prioritise cognitive, objective knowing. This review analyses 27 studies, published between 2007 and 2020, that draw on drama-based pedagogies to engage with First Nations content and concepts in early childhood, primary, secondary, and tertiary institutions. We found that drama provides powerful but often risky and unpredictable ways to enhance student, educator, and community learning, engagement, emotions, and relationships. The educator’s role is vital to enabling or preventing outcomes which contribute to the survival, dignity, and well-being of First Nations peoples. Ethical guidelines and issues must be carefully considered by anyone attempting to work in this complex, awkward space.
Stratified state aggregation (SSA) approach in real option valuation: combining price and grade uncertainties in tin mining projects
Authors: Ardhiansyah Mohammad Rahman , Adachi Tsuyoshi , Oda Junichiro 
Published: June 2022

AbstractThe only source of revenue for mining is the sale of its reserves. Therefore, a particular quantity of reserves and a specific selling price will generate a certain income. However, these income determinants are very unpredictable. Theoretically, real options (RO) substitute the discounted cash flow (DCF) approach to account for this uncertainty. Generally, RO quantify the uncertainty particularly related to price volatility. However, owing to its mathematical intricacy and application, the utility of RO is minimal. In addition, historical data analysis cannot be applied for spatial uncertainty related to grade uncertainty. Conventional RO approaches, such as the Black–Scholes method and lattice valuation technique, cannot measure a project with multiple uncertainties. In addition, these methods are mathematically complex and not sufficiently flexible for practical adaptation. This study proposes originality on simulation technique called stratified state aggregation (SSA) development that combined price and grade uncertainties in estimating the value of mining projects. For case study, a tin mining project of PT Timah Tbk in Indonesia was undertaken, specifically for short-term mine planning in underwater mining operations at two mining locations. We utilized the historical data natural logarithmic analysis to determine price uncertainty and conditional simulation to evaluate grade uncertainty. Our results indicated that mining uncertainties might be modeled using RO and value-added through SSA can be used to assess multi-uncertainty and multi-stage mining (rainbow option). The SSA decision aligned with the DCF method with improvement in uncertainty assessment. In addition, incorporating management flexibility may aid in alleviating concerns regarding the continuation or termination of a project.