bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence and clinical characteristics of spinal arteriovenous shunts: hospital-based surveillance in Okayama, Japan
Authors: Hiramatsu Masafumi , Ishibashi Ryota , Suzuki Etsuji , Miyazaki Yuko , Murai Satoshi , Takai Hiroki , Takasugi Yuji , Yamaoka Yoko , Nishi Kazuhiko , Takahashi Yu , Haruma Jun , Hishikawa Tomohito , Yasuhara Takao , Chin Masaki , Matsubara Shunji , Uno Masaaki , Tokunaga Koji , Sugiu Kenji , Date Isao 
Published: December 2021

OBJECTIVE
There have been no accurate surveillance data regarding the incidence rate of spinal arteriovenous shunts (SAVSs). Here, the authors investigate the epidemiology and clinical characteristics of SAVSs.

METHODS
The authors conducted multicenter hospital-based surveillance as an inventory survey at 8 core hospitals in Okayama Prefecture between April 1, 2009, and March 31, 2019. Consecutive patients who lived in Okayama and were diagnosed with SAVSs on angiographic studies were enrolled. The clinical characteristics and the incidence rates of each form of SAVS and the differences between SAVSs at different spinal levels were analyzed.

RESULTS
The authors identified a total of 45 patients with SAVSs, including 2 cases of spinal arteriovenous malformation, 5 cases of perimedullary arteriovenous fistula (AVF), 31 cases of spinal dural AVF (SDAVF), and 7 cases of spinal epidural AVF (SEAVF). The crude incidence rate was 0.234 per 100,000 person-years for all SAVSs including those at the craniocervical junction (CCJ) level. The incidence rate of SDAVF and SEAVF combined increased with advancing age in men only. In a comparative analysis between upper and lower spinal SDAVF/SEAVF, hemorrhage occurred in 7/14 cases (50%) at the CCJ/cervical level and in 0/24 cases (0%) at the thoracolumbar level (p = 0.0003). Venous congestion appeared in 1/14 cases (7%) at the CCJ/cervical level and in 23/24 cases (96%) at the thoracolumbar level (p < 0.0001).

CONCLUSIONS
The authors reported detailed incidence rates of SAVSs in Japan. There were some differences in clinical characteristics of SAVSs in the upper spinal levels and those in the lower spinal levels.
Association of intraoperative end-tidal carbon dioxide level with ablation volume during magnetic resonance–guided laser interstitial thermal therapy for mesial temporal lobe epilepsy
Authors: Hwang Brian Y. , Eremiev Alexander , Palla Adhith , Mampre David , Negoita Serban , Tsehay Yohannes K. , Kim Min Jae , Coogan Christopher , Kang Joon Y. , Anderson William S. 
Published: December 2021

OBJECTIVE
Maximal safe ablation of target structures during magnetic resonance–guided laser interstitial thermal therapy (MRgLiTT) is critical to achieving good seizure outcome in patients with mesial temporal lobe epilepsy (mTLE). The authors sought to determine whether intraoperative physiological variables are associated with ablation volume during MRgLiTT.

METHODS
Patients with mTLE who underwent MRgLiTT at our institution from 2014 to 2019 were retrospectively analyzed. Ablation volume was determined with volumetric analysis of intraoperative postablation MR images. Physiological parameters (systolic blood pressure [SBP], diastolic blood pressure [DBP], mean arterial pressure [MAP], end-tidal carbon dioxide [ETCO2]) measured 40 minutes prior to ablation were analyzed. Univariate and multivariate regression analyses were performed to determine independent predictors of ablation volume.

RESULTS
Forty-four patients met the inclusion criteria. The median (interquartile range) ablation volume was 4.27 (2.92–5.89) cm3, and median ablation energy was 7216 (6402–8784) J. The median MAP, SBP, DBP, and ETCO2 values measured during the 40-minute period leading up to ablation were 72.8 (66.2–81.5) mm Hg, 104.4 (96.4–114.4) mm Hg, 62.4 (54.1–69.8) mm Hg, and 34.1 (32.0–36.2) mm Hg, respectively. In univariate analysis, only total laser energy (r = 0.464, p = 0.003) and 40-minute average ETCO2 (r = −0.388, p = 0.012) were significantly associated with ablation volume. In multivariate analysis, only ETCO2 ≤ 33 mm Hg (p = 0.001) was significantly associated with ablation volume.

CONCLUSIONS
Total ablation energy and ETCO2, but not blood pressure, may significantly affect ablation volume in mTLE patients undergoing MRgLiTT. Mild hypocapnia was associated with increased extent of ablation. Intraoperative monitoring and modulation of ETCO2 may help improve extent of ablation, prediction of ablation volume, and potentially seizure outcome.
Management of fresh odontoid fractures using posterior C1–2 fixation without fusion: a long-term clinical follow-up study
Authors: Ma Fei , Fan Yuanhe , Liao Yehui , Tang Qiang , Tang Chao , Xu Shicai , Wang Qing , Lan Yongshu , Zhong Dejun 
Published: December 2021

OBJECTIVE
Posterior C1–2 fixation without fusion makes it possible to restore atlantoaxial motion after removing the implant, and it has been used as an alternative technique for odontoid fractures; however, the long-term efficacy of this technique remains uncertain. The purpose of the present study was to explore the long-term follow-up outcomes of patients with odontoid fractures who underwent posterior C1–2 fixation without fusion.

METHODS
A retrospective study was performed on 62 patients with type II/III fresh odontoid fractures who underwent posterior C1–2 fixation without fusion and were followed up for more than 5 years. The patients were divided into group A (23 patients with implant removal) and group B (39 patients without implant removal) based on whether they underwent a second surgery to remove the implant. The clinical outcomes were recorded and compared between the two groups. In group A, the range of motion (ROM) of C1–2 was calculated, and correlation analysis was performed to explore the factors that influence the ROM of C1–2.

RESULTS
A solid fracture fusion was found in all patients. At the final follow-up, no significant difference was found in visual analog scale score or American Spinal Injury Association Impairment Scale score between the two groups (p > 0.05), but patients in group A had a lower Neck Disability Index score and milder neck stiffness than did patients in group B (p < 0.05). In group A, 87.0% (20/23) of the patients had atlantoodontoid joint osteoarthritis at the final follow-up. In group A, the C1–2 ROM in rotation was 6.1° ± 4.5° at the final follow-up, whereas the C1–2 ROM in flexion-extension was 1.8° ± 1.2°. A negative correlation was found between the C1–2 ROM in rotation and the severity of tissue injury in the atlantoaxial region (r = –0.403, p = 0.024) and the degeneration of the atlantoodontoid joint (r = –0.586, p = 0.001).

CONCLUSIONS
Posterior C1–2 fixation without fusion can be used effectively for the management of fresh odontoid fractures. The removal of the implant can further improve the clinical efficacy, but satisfactory atlantoaxial motion cannot be maintained for a long time after implant removal. A surgeon should reconsider the contribution of posterior C1–2 fixation without fusion and secondary implant removal in preserving atlantoaxial mobility for patients with fresh odontoid fractures.
Pelatihan Penggolahan Sampah Organik Skala Rumah Tangga Menggunakan Metode Keranjang Takakura
Authors: Neri Puspita Sari  , Benriwati Maharmi  , Zaiyar  , Yulia Setiani  , Silfia Rini  
Published: December 2021

Every day people always produce household waste. In an average day each resident produces 2-3 liters of waste. To reduce the amount of waste that is disposed of in the TPA, the community needs to carry out their own waste processing techniques. The most appropriate method of processing organic waste is to use the compost. Compost is an effort to process organic waste through a controlled decomposition process. The main product of composting is environmental cleanliness, because the amount of disposing organic waste in the landfill that can be reduced. Subsequence, it can be obtained the compost yield as another advantage. Composting with the Takakura method is very suitable for tropical areas and household scale.
DIFFERENCES OF MALE AND FEMALE STUDENTS’ UNDERHAND SERVES ABILITY IN MINI VOLLEY BALL BASED ON DEMONSTRATION METHOD
Authors: Syah Remon , Anita Rini 
Published: December 2021

This research is aimed at finding whether demonstration method could enhance students’ ability in conducting underhand services at mini volley ball and how it is viewed in gender differences. The research design was a classroom action research by using two cycles at the fourth grade of SDN 20 Bungo Tanjung. The research result shows that there is an improvement on students’ underhand serves ability in applying demonstrastion method for about 23,8%. Cyle 1 is 66,7 % while at cycle 2 is 90,5%. Meanwhile for gender differences, male students are much better than female students in conducting underhand serves. In short, the use of demonstration method can enhance students’ ability in doing underhand serves.
Manajemen dan Peran BAZNAS Mengatasi Dampak Pademi Covid-19 Provinsi Bengkulu
Authors: Alfiah Esti , Sumarni Yenti 
Published: December 2021

Di masa pandemi ini lembaga-lembaga amil zakat dituntut untuk dapat berkontribusi dalam penanganan masalah ekonomi yang diakibatkan oleh pandemi covid-19. Yang mana zakat di khususkan untuk delapan golongan ashnaf saja, akan tetapi kondisi dari pandemi covid-19 ini berdampak terhadap banyak hal. Sehingga tujuan penelitian ini untuk mengetahui bagaimana Manajemen dan peran lembaga amil zakat terhadap penggunaan dana zakat pada korban covid-19. Penelitian menggunakan metode deskriptif analisis. Bahwa manajemen BAZNAS dimasa pademi dengan terkait 3 hal yaitu SDI, Money dan Methods. Secara keseluruhan telah baik, sehingga peran BAZNAS dalam mengatasi dampak selama pademi teratasi dan tujuan BAZNAS tercapai.
A parametric approach to fuzzy multi-objective linear fractional program: An alpha cut based method
Authors: Borza Mojtaba , Rambely Azmin Sham 
Published: December 2021

In the multi-objective programming problem (MOPP), finding an efficient solution is challenging and partially encompasses some difficulties in practice. This paper presents an approach to address the multi-objective linear fractional programing problem with fuzzy coefficients (FMOLFPP). In the method, at first, the concept of α - cuts is used to change the fuzzy numbers into intervals. Therefore, the fuzzy problem is further changed into an interval-valued linear fractional programming problem (IVLFPP). Afterward, this problem is transformed into a linear programming problem (LPP) using a parametric approach and the weighted sum method. It is proven that the solution resulted from the LPP is at least a weakly ɛ - efficient solution. Two examples are given to illustrate the method.
Longitudinal Healthcare Utilization and Costs in Parkinson’s Disease: Pre-Diagnosis to 9 Years After
Authors: Soh Emily Ming Li , Neo Shermyn , Saffari Seyed Ehsan , Wong Aidan Sheng Yong , Ganesan Ganga , Li Wei , Ng Hwee Lan , Xu Zheyu , Tay Kay Yaw , Au Wing Lok , Tan Kelvin Bryan , Tan Louis Chew Seng 
Published: December 2021

Background: There is currently insufficient long-term data on costs of treatment in patients with Parkinson’s disease (PD), which is chronic and progressive, and associated with substantial healthcare costs. Identifying patterns in healthcare utilization and cost may illuminate further discussion on early intervention. Objective: To characterize long-term healthcare utilization and costs of PD in newly diagnosed patients managed by movement disorder specialists. Methods: Using a longitudinal matched-cohort study of linked data from the National Neuroscience Institute Parkinson’s disease and Movement Disorder and healthcare administrative databases in Singapore from 2008–2017, we compared healthcare utilization and costs between patients and controls matched on age, sex, race, and Charlson Comorbidity Index score. Results: 1,162 patients met study inclusion criteria and 1,157 matched controls were identified. The total mean annual healthcare cost (at 2017 costs) was significantly increased in patients compared to controls from years 1–9 post-diagnosis. The increased cost was observed 2 years before diagnosis (USD2322 vs. 2052; p < 0.001). Mean annual cost attributable to PD increased from USD1854 at 1-year post-diagnosis to USD2652 at 9 years. Over 9 years, average costs were significantly higher across all domains of healthcare utilization except primary care—cost of intermediate and long-term care was increased by a factor of 2.5, specialist care by 2.3, emergency department visits by 1.6, and hospital admissions by 1.3. Conclusion: PD results in higher healthcare utilization and costs. Pre-diagnosis increase in healthcare utilization observed in patients supports the presence of prodromal PD symptoms and may present an opportunity for early diagnosis.
“PROBE”ing the Role of Cytoreductive Nephrectomy in Advanced Renal Cancer
Authors: Bell Hannah , Cotta Brittney H. , Salami Simpa S. , Kim Hyung , Vaishampayan Ulka 
Published: December 2021

The Southwest Oncology Group (SWOG)1931 trial, also known as PROBE (ClinicalTrials.gov Identifier: NCT04510597) is a phase III study evaluating the role of cytoreductive nephrectomy (CN) in metastatic renal cell cancer (RCC). Kidney cancer presenting with synchronous metastases has demonstrated shorter survival outcome compared to the patients relapsing with metastases after nephrectomy. Previously, CN has been associated with survival improvement when interferon-based systemic therapy was used. In the setting of antivascular therapy sunitinib, a prospective randomized clinical trial demonstrated no benefit of CN. Immune checkpoint-based combination therapy has now become the standard-of-care in the frontline setting for RCC. The role of nephrectomy or primary resection has not been evaluated in the setting of immune checkpoint-based systemic therapy. The sequence and optimal timing of nephrectomy is also not established. The PROBE study design attempts to answer the question whether CN has an impact on overall survival outcomes in RCC within the context of immune checkpoint-based combination regimens. The study requires starting with systemic therapy; any one of the FDA approved immunotherapy-based regimens at the time the study was activated are permitted. The disease status and response are evaluated at 9–12 weeks of therapy and then consented patients are randomized 1:1 to receive CN or to continue systemic therapy. The patients who have rapid disease progression are considered ineligible for randomization as they need a switch in systemic therapy. Both groups should continue systemic therapy as long as they are tolerating the treatment and continuing to derive clinical benefit. Quality-of-life, tumor genomic testing, microbiome, radiomics and circulating tumor DNA assessments as predictive biomarkers are planned as study correlatives. The study hypothesis is that CN will improve OS in synchronous metastatic RCC when surgery is performed after starting systemic immune checkpoint-based combination therapy. A potential mechanism leading to improved survival is the broader antigen spread and higher neoantigen load enabled by the primary tumor enhancing the efficacy of the immune therapy. CN after initial systemic therapy would help select the patient subset most likely to benefit and will potentially enable eradication of immune resistant clones within the primary tumor.
Historical origins of modern vocal and instrumental performance in Ukraine at the beginning of the XXI century
Authors: Dyman Tatiana , Shulgina Valeria 
Published: December 2021

The purpose of the article is to determine the historical origins of vocal-instrumental performance from ancient times to the present day, in revealing the influence of some prominent personalities on the further development of vocal and instrumental art and the selection of famous modern ensembles, which are the face of the late XX-early XXI century. Methodology. The research methodology is based on methods of analysis and synthesis, comparative method, method of historicism, and interpretation. The combination of such a technological process makes it possible to more fully disclose the research topic. Scientific novelty. The scientific novelty lies in the systematization of the material on the development of vocal-instrumental performance in Ukraine from its origins to the beginning of the XXI century and the substantiation of the originality of performance in different historical circumstances. Conclusions. Performance as an aspect of the synthesis of the arts over the centuries has had various forms of self-expression. It developed in the conditions of real events, improved according to time, and acquired certain advantages at the turn of the century in different historical periods of spiritual upsurge. Kobzars, bandura players, chamber-instrumental and vocal-instrumental ensembles have passed a difficult way of professional growth and laid the foundation for further development of performing arts. The formation of the national school and the development of bandura performance in Ukraine took place thanks to the great work of the outstanding composer Mykola Lysenko, which inspired the creative work of Ukrainian artists Hnat Khotkevych, Serhiy Bashtan, and others. In the 70s of the XX century ensembles enriched their concert repertoire with arrangements of Ukrainian folk songs and compositions of outstanding composers of their time. Vocal-instrumental ensemble "DakhaBrakha", born in modern conditions at the beginning of the XXI century (2004) stylistically diversified the direction of its activities, synthesizing folk and contemporary music.
Keywords: historical milestones of vocal-instrumental development performance, synthesis of arts, the figure of Gregory Skovoroda as a philosopher, composer and musician, activity of the founder of the national school Mykola Lysenko, bandura performance, Ukrainian group "DakhaBrakha".
Ternopil branch of the Musical Institute named after Mykola Lysenko as a cultural and educational center of Ternopil (1st half of XX century)
Authors: Spolska Olena 
Published: December 2021

The purpose of the article is to analyze the historical and cultural background and the main aspects of the formation of professional piano performance in Ternopil in the late nineteenth - first half of the twentieth century on the example of VMIL branch activity. Methodology. The methodological basis of the publication is historical-stylistic and comparative approaches, methods of historical-cultural discourse (according to V. Cherkasov). The formation of professional piano performance is considered in terms of musicological and stylistic approaches in broader cultural, educational, and musical-pedagogical contexts. The problem of studying the regionalism of music and performance centers and schools as a dynamic historical and cultural phenomenon is actualized. A thorough study of the history of regional piano educational centers and performing schools has been the subject of a number of musicological studies. In particular, the works of N. Kashkadamova, T. Starukh, L. Mazepa, and others are dedicated to the piano art of Lviv, its artistic education, and cultural institutions. Scientific Novelty. Based on the study of scientific and archival sources, we can see that the educational and pedagogical traditions of the Higher Music Institute named after M. Lysenko as the first Ukrainian professional center and its branches in Eastern Galicia have continued in the activities of pianists, teachers, and performers in Ukraine and abroad, mainly Western Of Ukraine. Attention is focused on the opening and initial stage of the branch of the Lysenko Higher Music Institute (VMIL) in Ternopil, in particular, on the activities of piano teachers. Based on historical, comparative, and individual approaches, the role of individual performers, composers, and teachers as the founders of piano performance in the region is highlighted. Thus, the novelty of the article is to trace the initial stage of the formation of piano performance in Ternopil in the late nineteenth - first third of the twentieth century. as a process of transition from the amateur period to academic performance and professional music education. Conclusions are made about the decisive role of the branch of the Higher Music Institute named after M. Lysenko (VMIL) in Ternopil and its founders, in particular, Iryna Krykh (Lyubchakova) and Yuri Krykh, in the development of music education and performance in the region.
Keywords: musical culture of Western Ukraine, end of XIX – first half of XX century, piano performance, Higher Music Institute M. Lysenko (VMIL), pianists, performers and lecturers of Ternopil.
Stage as a universe of human communicative activity
Authors: Tanska Lyudmyla 
Published: December 2021

The purpose of the article. The research is connected with the definition of culturological bases of synthetic image formation in the system of modern communication and opening of stage space as a communicative phenomenon in the context of the transformation of spectacular cultural practices of the XX century. The research methodology consists of theoretical and interpretive models of comparative and systematic approaches to the definition of stage space as cultural integrity. The scientific novelty of the work is to reveal the peculiarities of cultural creation of stage space in the twentieth century, when artists turned to previous systems of artistic reflection, figurative distinctions of the stage in culture. Emphasis is placed on the relevance of the study of the communicative properties of the stage in cultural construction. The stage can be remote, virtual, chamber, monumental. However, the scene from the category of subject-spatial dimension passes into another dimension - time. On the stage you can not break the unity of time and space, the stage is the unity of action and event, and also presents a certain space-time - chronotope, human image, an image of the day. Conclusions. The revival of the pre-cultural, pre-civilization in the broad progressive sense of the word world of the stage becomes the basis for a polymorphic definition of the communicative dimension of the stage as such. Stage space in the modern dimension requires a comprehensive interdisciplinary study, which focuses on discursive analysis, phenomenological and aesthetic studies of the categories "stage", "act", "action", "event", "creativity", etc. The article only raises the issue of interdisciplinary research tools. Further elaboration of the problem field requires separate investigations.
Keywords: culture, universe, scene, action, event, chronotope, scenics.
Modern media resources in the communication system of an accordionist
Authors: Bendas Daryna 
Published: December 2021

The purpose of the Article. The article is devoted to the study of modern media resources as ways of communication between an accordionist-performer and the audience on the example of using the world’s most popular social networks: Facebook, YouTube, Instagram. The research methodology involves the use of methods of analysis and synthesis, systematization, generalization. Scientific novelty. Defining the components of the digital compass of a domestic accordionist in the context of the digital strategy of Europe. Conclusions. The study showed that in the creative activity of musicians, including accordionists, there is a rapid development of the latest means of communication. The online media, which are most often used in the music sphere, are characterized, the specifics of the content of popular social networks depending on the target audience are analyzed on specific examples. The main problems associated with the use of the latest methods of communication by domestic artists have been identified: a lower level of activity in the Internet space compared to foreign artists, as well as a “digital divide” between different generations. The “Digital Compass of a Modern Accordionist” has been proposed as a tool for solving the above problems, and its components have been identified.
Keywords: music culture, accordion art, media resources, social networks, information technologies, communication, intercultural communication.