bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demonstration of weak measurements, projective measurements, and quantum-to-classical transitions in ultrafast free electron-photon interactions
Authors: Pan Yiming , Cohen Eliahu , Karimi Ebrahim , Gover Avraham , Schönenberger Norbert , Chlouba Tomáš , Wang Kangpeng , Nehemia Saar , Hommelhoff Peter , Kaminer Ido , Aharonov Yakir 
Published: July 2022

Abstract
How does the quantum-to-classical transition of measurement occur? This question is vital for both foundations and applications of quantum mechanics. Here, we develop a new measurement-based framework for characterizing the classical and quantum free electron-photon interactions and then experimentally test it. We first analyze the transition from projective to weak measurement in generic light-matter interactions and show that any classical electron-laser-beam interaction can be represented as an outcome of a weak measurement. In particular, the appearance of classical point-particle acceleration is an example of an amplified weak value resulting from weak measurement. A universal factor, exp(Γ2 /2) , quantifies the measurement regimes and their transition from quantum to classical, where Γ corresponds to the ratio between the electron wavepacket size and the optical wavelength. This measurement-based formulation is experimentally verified in both limits of photon-induced near-field electron microscopy and the classical acceleration regime using a dielectric laser accelerator. Our results shed new light on the transition from quantum to classical electrodynamics, enabling to employ the essence of wave-particle duality of both light and electrons in quantum measurement for exploring and applying many quantum and classical light-matter interactions.
An integrated model for examining teachers’ intentions to use augmented reality in science courses
Authors: ates huseyin , garzon juan 
Published: July 2022

Abstract
Many studies show that augmented reality (AR) provides multiple benefits to science education, including learning gains, motivation to learn, and collaborative learning. However, while using AR largely depends on the teachers’ willingness, existing literature lacks studies that identify teachers’ intentions to use this technology. This study proposes a model to predict science teachers’ intentions to use AR in their classes. Our model merges the Theory of Planned Behavior and the Unified Theory of Acceptance and Use of Technology 2. It includes nine hypotheses that were tested with 451 science teachers from different cities in Turkey. The results indicate that our model identifies the factors affecting teachers’ intentions to use AR with a stronger explanatory power than the referenced theories. Besides, all hypotheses within the proposed model were statistically supported in determining antecedents of science teachers' intentions. Finally, the study contributes to the theory and practice by focusing on the psychological aspects required for explaining science teachers’ intentions to use AR.
Directional fabricating of flexible and compressible cellulose nanofibril composite aerogel with excellent thermal insulation, flame-retardancy and radiative cooling for efficient thermal management
Authors: Zhao Jiaojiao , Zhou Jianhua , Li Hong , Xiao Anguo 
Published: July 2022

Abstract
In order to reduce the thermal discomfort and fire accidents caused by overheating of electronics and high temperature of buildings, high-performance thermal insulation and fire-resistant materials are urgently desirable. Cellulose nanofiber aerogel derived from regenerative resources holds wide promise in the field of thermal insulation, but its inherent flammability, poor mechanical strength and water resistance make it face great challenges in practical application. Herein, a lightweight, porous, anisotropic silylated cellulose nanofiber/hydroxylated boron nitride nanosheet (Si-CNF/BNNS) composite aerogel was prepared by unidirectional freeze-casting technique. Attributed to the aligned structure, Si-CNF/BNNS aerogel was robust axially and compressible radially. The thermal conductivity of aerogel was 0.0621 W·m−1·K−1 in the axial direction and 0.0339 W·m−1·K−1 in the radial direction, demonstrating an anisotropic thermal insulation performance. In addition, aerogel also exhibited excellent flame retardant, hydrophobic and radiative cooling properties, as evidenced by extremely low peak heat release rate of 14.05 kW/m2, water contact angle of 136.6° and high solar reflectivity. This high-performance anisotropic Si-CNF/BNNS aerogel is promising in improving thermal comfort and environmental safety, showing its great potential in electronic packaging and energy efficient buildings.
Storm surges during IANOS Medicane
Authors: Androulidakis Yannis , Makris Christos , Mallios Zissis , Pytharoulis Ioannis , Baltikas Vassilis , Krestenitis Yannis 
Published: July 2022

Abstract
The IANOS Medicane was one the most severe storms that have formed in the Mediterranean Sea with Category 2 Hurricane characteristics. The storm induced a significant increase of sea level elevation along its pathway and caused the occurrence of storm surges at the central Ionian Sea with consequent impacts on coastal regions of the Ionian islands and western Greece. A multi-platform approach, based on hydrodynamic ocean simulations, nested to meteorological and coastal flooding simulations, is used in combination with field and satellite observations to describe the marine weather conditions, the storm surge characteristics, and the coastal inundation processes due to the impact of IANOS Medicane in September 2020. Both wind and atmospheric pressure patterns affected the storm surge variability over the Ionian Sea. The direct intrusion of the Medicane from the central Mediterranean Sea towards the Ionian Sea formed storm surges over several coastal areas, even before the storm's landfall, due to the accompanying onshore currents. Storm surges in the order of 30 cm generated extensive flooding over lowland coastal areas, as confirmed by both satellite (Normalized Difference Water Index: NDWI) and numerical (coastal inundation modeling) data. Satellite-derived and simulated estimations showed that, in specific coastal regions, the run-up of seawater extended up to 200 m inland, depending on the hydraulic connectivity between the lowland areas, which determined the inundation extents during the storm surge.
Characterisation of Patients Referred to a Tertiary-Level Inherited Cardiac Condition Clinic with Suspected Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC)
Authors: Aljehani A , Kew T , Baig S , Cox H , LC Sommerfeld , Ensam B , Kalla M , RP Steeds , Fabritz L 
Published: July 2022

Abstract
BackgroundArrhythmogenic right ventricular cardiomyopathy (ARVC) or arrhythmogenic cardiomyopathy is a rare inherited disease with incomplete penetrance and an environmental component. As ARVC is a common cause of sudden cardiac death in young adults, which can be the first symptom, recognition of early ARVC is important. Data on the different stages of ARVC remains scarce. The purpose of this study is to describe the initial presentation and cardiac phenotype of early and definite ARVC for patients seen at a tertiary service.MethodsThis is a single centre, observational cohort study of patients with early and definite ARVC seen at the Inherited Cardiac Conditions services at University Hospital Birmingham (UHB) in the period 2010–2021. Patients were identified by interrogation of digital health records, medical history, imaging and by examining 12-lead electrocardiograms (ECG).ResultThe records of 1451 patients were reviewed; of those, 165 patients were at risk of ARVC (mean age 41 ± 17 years, 56% male). 60 patients fulfilled task force criteria for definite ARVC diagnosis (n = 40, 67% males), and 37 (71%) of them carried a known pathogenic variant. The remaining 105 patients (50% males) showed early features, and of these 45 (63%) carried a known pathogenic variant. Patients in the definite group were more symptomatic, with palpitations (57% vs. 17%), syncope (35% vs. 6%) and shortness of breath (28% vs. 5%, p < 0.001). T-wave inversion in V1-V3 and epsilon waves were observed only in the definite group. Both PR interval and QRS duration were longer in the definite (170 ± 34 ms and 100 ± 19 ms, p < 0.001) compared to (149 ± 25 and 91 ± 14 ms, p = 0.005). Patients with definite ARVC had significantly larger RV end diastolic areas and significantly reduced biventricular function (RVEDA = 27 ± 10 cm2, RVFAC = 37 ± 11% and EF = 56 ± 12%) compared to the early group (RVEDA = 18 ± 4 cm2, RVFAC 49 ± 6% and LVEF 64 ± 7%, p < 0.001). Sustained ventricular tachycardia (VT) occurred more frequently in the definite group compared to the early group (27% vs. 2%, p < 0.001). Ventricular fibrillation was observed in the definite group only (8 of 60 patients, 13%).ConclusionAlthough definite ARVC patients showed more electrical and structural changes and major adverse cardiac events, some ARVC patients classified as having early ARVC experienced sustained VT. Improving screening methodology is necessary to identify the group most at risk in the future.
Prediction of climate change effects on Siberian Crane (Grus leucogeranus ) habitat suitability by using ensemble modeling in Asia Wetlands
Authors: ansari amir 
Published: July 2022

Abstract
The Siberian Crane (Grus leucogeranus) is the third rarest and the most endangered crane species in the world. This study aimed at predicting the effect of climate change on Siberian Crane habitat suitability of breeding range and wintering range in Asia Wetlands by using ensemble modeling under future climate scenarios before the year 2050. In this regard, we used 4 modeling methods, Surface Range Envelop (SRE), Random Forest (RF), Classification Tree Analysis (CTA) and Flexible Discriminant Analysis (FDA) to determine the relationships between the species occurrence and bioclimatic variables under the ensemble framework by using Biomod2 and R software. The results showed that the AUC values were greater than 0.9 and functioning of all models was excellent. The Temperature Seasonality and Temperature Annual Range in the breeding range and Temperature Seasonality and Mean Temperature of Coldest Quarter in the wintering range had the most important role for habitat suitability of this species and respectively 101.07% and 136.27% changes was justified in Siberian Crane habitat suitability. Under RCP2.6 and RCP8.5 climate scenario for Siberian Crane breeding and wintering range, it is possible that climate change will cause a 100% loss of suitable habitat in West Sibera, and a 25.28% loss in Iran and China by 2050. The results of this study can be used in planning and conservation of crane species.
The spatial distribution of soluble organic matter and its relationship to minerals in the asteroid (162173) Ryugu.
Authors: Hashiguchi Minako , Aoki Dan , Fukushima Kazuhiko , Naraoka Hiroshi , Takano Yoshinori , Jason Dworkin P. , Jose Aponte C. , Jamie Elsila E. , John Eiler M. , Furukawa Yoshihiro , Furusho Aogu , Daniel Glavin P. , Graham Heather V. , Hamase Kenji , Norbert Hertkorn , Isa Junko , Koga Toshiki , Hannah McLain L. , Mita Hajime , Oba Yasuhiro , Ogawa Nanako O. , Ohkouchi Naohiko , Orthous-Daunay Francois-Regis , Parker Eric T. , Alexander Ruf , Sakaki Saburo , Philippe Schmitt-Kopplin , Sugahara Haruna , Roland Thissen , Véronique Vuitton , Wolters Cédric , Yoshimura Toshihiro , Yurimoto Hisayoshi , Nakamura Tomoki , Noguchi Takaaki , Okazaki Ryuji , Yabuta Hikaru , Sakamoto Kanako , Tachibana Shogo , Yada Toru , Nishimura Masahiro , Nakato Aiko , Miyazaki Akiko , Yogata Kasumi , Abe Masanao , Usui Tomohiro , Yoshikawa Makoto , Saiki Takanao , Tanaka Satoshi , Terui Fuyuto , Nakazawa Satoru , Watanabe Sei-ichiro , Tsuda Yuichi 
Published: July 2022

Abstract
We performed in-situ analysis on a ~1 mm-sized Ryugu grain A0080 returned by the Hayabusa2 spacecraft to investigate the relationship of soluble organic matter (SOM) to minerals. The DESI-HRMS (desorption electrospray ionization-high resolution mass spectrometry) imaging using methanol spray identified more than 200 soluble organic compounds, which were assigned as CHN, CHO, CHO-Na (sodium adducted), and CHNO in molecular composition. Heterogeneous spatial distribution was observed for different compound classes of SOM as well as among the same alkylated homologues on the sample surface. The A0080 sample showed similar mineralogy to that of CI chondrite and contained two different lithologies, which are rich in magnetite, pyrrhotite, and dolomite (lithology 1) and poor in those minerals (lithology 2). CHN compounds were relatively concentrated in lithology 1 than in lithology 2, on the other hand, CHO, CHO-Na, and CHNO compounds were distributed in both lithologies. Such different spatial distribution of SOM is the result of interaction of the SOM with minerals, during precipitation of the SOM via fluid activity, or could be due to difference in transportation efficiencies of SOMs in aqueous fluid. However, organic-related ions measured by ToF-SIMS did not coincide with the spatial distribution revealed by DESI-HRMS imaging, indicating that the ToF-SIMS data would be mainly derived from methanol-insoluble organic matter in A0080. Alkylated homologues of CHN compounds with large C number appeared more abundant in lithology 2 than lithology 1. In contrast, fragments of the Murchison meteorite showed different features to of A0080, implying different formation or growth mechanisms for the alkylated CHN compounds by interaction with fluid and minerals on Murchison parent body and asteroid Ryugu. This difference might be mainly attributed to the carbonate grains, which would have played as a catalyst for CH2 growth of CHN compounds. Future in-situ analysis of CI chondrite will provide more reliable constraints for the history of soluble organic compounds in asteroid Ryugu.
Earthquake and Rainfall Induced Landslide Hazard Assessment of Kutupalong Rohingya Camp Using Meteorological and Geological Information
Authors: Samm-A Anika , Kamal A. S. M. Maksud , Rahman Md. Zillur 
Published: July 2022

Abstract
The study aims to assess the landslide hazard scenario of the Kutupalong Rohingya camp, considered one of the largest humanitarian shelters for conflict-fled people. The camp area lying in a prominent tectonic setting and meteorological environment, is vulnerable to landslide hazards, specifically in the monsoon season. The worst-case scenario of earthquake and rainfall occurrence at the same time or one after another is considered in this study. Landslide favorable parameters (topographic, soil physical property, and contributing factors) are designed in the study to identify the hazard-prone areas through the factor of safety computation. Topographic parameters are prepared by combining field investigation and remote sensing-based information. Soil physical properties are designed in two different models to account for their uncertainties; normal probabilistic distribution and interpolation-based spatial distribution. The contributing factors (earthquake and rainfall) have been assessed using the probabilistic approach. The Peak Ground Acceleration (PGA) exceedance and rainfall intensities of 50, 75, 100, 200, and 475 years return period are applied in the factor of safety calculation. The factor of safety calculation has been run using two different methods; Monte-Carlo simulation using Python scripts and direct estimation method. Different duration (rainfall intensity) scenarios are also modeled to estimate the vulnerable areas in these models. The findings of the study are finally validated against field investigation-based landslide inventory with more than 84% accuracy at a 90% confidence interval.
UBE2E2-induced p62 overexpression promotes Snail-mediated epithelial-mesenchymal transition and metastasis in ovarian cancer
Authors: Hong Xiaoling , Ma Ning , Li Danjie , Zhang Mengwen , Dong Wenqiuzi , Huang Jie , Ci Xinxin , Zhang Songling 
Published: July 2022

Abstract
Dissemination of ovarian cancer (OvCa) cells can lead to inoperable metastatic lesions in the bowel and omentum, which have a poor prognosis despite surgical and chemotherapeutical options. A better understanding of the mechanisms underlying metastasis is urgently needed. In this study, bioinformatics analyses revealed that UBE2E2, a less-studied ubiquitin (Ub)-conjugating enzyme (E2), was upregulated in OvCa and was associated with poor prognosis. Subsequently, we performed western blot analysis and IHC staining with 26 HGSOC and 26 normal ovarian tissue samples, which further confirmed that UBE2E2 protein is highly expressed in OvCa tissue but almost not expressed in normal tissue. Furthermore, the silencing of UBE2E2 blocked OvCa cell migration, epithelial-mesenchymal transition (EMT) and metastasis in vitro, whereas UBE2E2 overexpression exerted the opposite effects. Mechanistically, UBE2E2 promoted p62 accumulation and increased the activity of the Nrf2-antioxidant response element (ARE) system, which ultimately activated the Snail signaling pathway by inhibiting the ubiquitin-mediated degradation of Snail. Furthermore, our results confirmed that mutations in the active site cysteine (Cys139) impaired both the function and cellular distribution of UBE2E2. More importantly, the deletion of UBE2E2 reduced tumorigenicity and metastasis in a xenograft ovarian cancer mouse model. Taken together, our study findings reveal the role of the UBE2E2-Nrf2-p62-Snail signaling axis in OvCa and thus provides novel therapeutic targets for the prevention of metastasis in OvCa.
Association between Nutrient Patterns and Hyperuricemia: Mediation Analysis Involving Obesity Indicators for NHANES study
Authors: Wang Juping , Chen Shuting , Zhao Junkang , Liang Jie , Gao Xue , Gao Qian , He Simin , Wang Tong 
Published: July 2022

Abstract
Background: Diet had long been hypothesized to play an important role in hyperuricemia and weight gain was the stronger factor associated with the rise in serum urate. We aim to clarify the mediating role of obesity in the relationship between diet and hyperuricemia and further determine whether the weight-loss diet is an effective way to prevent hyperuricemia. Methods: This cross-sectional study analyzed representative samples of the United States (n=20081; NHANES 2007-2016) adults. Nutrient patterns were derived with two methods: principal component analysis (PCA) and reduced rank regression (RRR) with obesity. Logistic regression and multivariable linear regression were applied to analyze the association between nutrient patterns in obesity and hyperuricemia. Mediation analyses were used to determine if four obesity indicators, including body mass index (BMI), waist circumference (WC), visceral adiposity index (VAI) and lipid accumulation product Index (LAP), mediated nutrient patterns and hyperuricemia relationship. Results: PCA revealed three nutrient patterns (including “low energy diet”, “lower vitamin A, C, K pattern” and “vitamin B group”) and only vitamin B group had a total effect on hyperuricemia. RRR resulted in one main nutrient pattern associated with obesity, which is characterized by high fat and low vitamin levels and was significantly associated with hyperuricemia. Mediation analysis showed that obesity mostly or even completely mediated the relationship between nutrient patterns and hyperuricemia, especially traditional obesity indicators play a key intermediary effect. Proportion of indirect effect for BMI and WC were as high as 53.34 and 59.69, respectively.Conclusions: Our findings suggest that the direct effect of diet on hyperuricemia is weak, and obesity plays a critical mediated role in the pathway between diet and hyperuricemia, which confirms that weight-loss diet may be useful in preventing hyperuricemia.
The Role Of Systemic Immune Inflammatory Index To Show The Active Lesion In The Patients With Multiple Sclerosis
Authors: Gokce Seyda Figul , Bolayir Asli , Cigdem Burhanettin , Yildiz Bulent 
Published: July 2022

Abstract
Background: Multiple Sclerosis (MS) has two pathophysiological processes, one is inflammatory and the other is degenerative. We searched the relation between inflammatory biomarkers within the serums of patients who have active lesions in neuroimaging, and the existence, number, and localization of active lesions, as an indicator of the inflammatory process. Also, regardless of the imaging, we aim to detect the inflammatory period in which clinical, radiological follow-up, and disease-modifying treatments are effective with serum parameters.Methods: One hundred eighty six MS patients, presented to our hospital between January 2016 to November 2021 and 94 age-and- sex-matched healthy volunteers were recruited for our study. While 99 patients had active lesions in magnetic resonance imaging, 87 patients didn’t have any active lesion. Neutrophil/lymphocyte (NLR), platelet/lymphocyte (PLR), monocyte/lymphocyte (MLR) ratios were determined. SII (systemic immune inflammatory index) value was calculated according to the platelet X neutrophil/lymphocyte ratio formula.Results: NLR, MLR and especially PLR, SII ratios were found to be statistically highest in the patient group with active lesions. According to the presence of active lesions, cut-off values for MLR, PLR, NLR and SII were respectively 0.18, 1.53 and 117.15, 434.45.Conclusions: We found that SII and PLR values were correlated with radiological activity. As easily accessible, inexpensive markers, SII and PLR can detect the inflammatory period in which patients have a higher response to treatment, with sufficient sensitivity and specificity. It can also be a helpful evaluation candidate for the presence of radiological activity.
Mo content-depended competition between the Cr2O3 enrichment and selective dissolution of CoCrFeNiMox high entropy alloys
Authors: Wang Xian-Zong , Hu Qian , Ye Cheng-Ping , Zhang Shang-Chen , Du Cheng-Feng , Wang Haifeng 
Published: July 2022

Abstract
The corrosion and passivation behavior of CoCrFeNiMox (x = 0, 0.2, 0.4, 0.6, 0.8, and 1.0) high entropy alloys (HEAs) are investigated. With the addition of Mo, increasing Mo and Cr riched σ/μ phases precipitate from the primary FCC phase. The corrosion resistance of the CoCrFeNiMox HEAs strongly depends on the phase structure and the passive film formed on the surface. Generally, Mo promotes the selective dissolution of the FCC phase and the enrichment of Cr2O3 in the passive film, the former deteriorates the corrosion resistance while the latter enhances it. Interestingly, the hypoeutectic Mo0.6 exhibits a higher corrosion resistance than that of Mo0.4, eutectic Mo0.8, and hypereutectic Mo1. Analysis of surface passive film the composition of alloy phases implies that the Cr2O3 enrichment dominates in Mo0.6 while selective dissolution governs in Mox (x = 0.4, 0.8, and 1.0). Mo content-depended competition between the Cr2O3 enrichment and selective dissolution is discussed.