bluuebunny/crossref_metadata_2025_split huggingface dataset:
Special and Differential Treatment as If It Could Be Reformed
Authors: Sauvé Pierre 
Published: November 2022

The central question posed by the longstanding debate among World Trade Organization (WTO) Members over special and differential treatment (S&amp;DT) is how best to address legitimate demands for differentiation. Should this be done by replacing the self-designation of development status by a set of objective metrics distinguishing different categories of WTO Members? Or should Members alternatively focus their efforts on addressing objectively assessed capacities and needs in a more customized manner and on a case by case and agreement-specific basis? This note’s review of the S&amp;DT debate suggests that rather than focusing on the divisive issue of development status, where prospects for consensus appear non-existent, WTO Members should design S&amp;DT support focusing on objectively assessed negotiating and implementation needs to which targeted Aid for Trade would respond. A forward-looking approach to differentiation within the WTO requires that an altogether different narrative on trade and development take root in the organization, one that ascribes to trade (and to trade policy) a key supportive role in development trajectories. All too often, S&amp;DT demands are formulated as if multilateral rules are inherently inimical to the development needs and aspirations of the world’s poorest nations. The note advances several reform options in charting a forward-looking S&amp;DT agenda.
Trade and development, trade governance, developing countries, least developed countries, special and differential treatment, World Trade Organization
La gestión integral de la seguridad en la educación primaria
Authors: Leal Acanda Luis Dimas , Martínez Gandol Carlos , Martínez Gandol Yander 
Published: November 2022

El trabajo que se presenta es resultado de dos proyectos de investigación Saneamiento y protección de ecosistemas asociados a comunidades impactadas por el cambio climático e Implementación de la Tarea Vida y evaluación de la Gestión Ambiental de la Universidad de Holguín. Tiene como objetivo demostrar la importancia de la gestión integral de la seguridad en centros de la Educación Primaria. Se utilizaron métodos del nivel teórico como: análisis-síntesis, inducción-deducción, que permitieron procesar la información consultada, elaborar la fundamentación teórica de la investigación, así como interpretar los resultados obtenidos con la aplicación de métodos empíricos como la observación que permitió identificar las principales insuficiencias de los maestros y educandos. Como resultado se aborda el estudio realizado sobre el proceso de la gestión integral de la seguridad para la gestión de la reducción del riesgo de desastres en centros de la Educación Primaria.
Palabras clave: riesgo; peligro; vulnerabilidad; Tarea Vida.
O currículo por projetos na dialética de Michel Foucault: desmistificando mecanismos de controle nos espaços escolares
Authors: Almeida Silva Cristina , Camba Mariangela 
Published: November 2022

Evidenciamos neste artigo a essencialidade da prática de projetos como forma de propor novas conjecturas de repensar o currículo e os espaços educativos no contexto escolar, desmistificando evidências correlacionadas a quatro mecanismos de controle referenciados na obra de Foucault (1975) - “Vigiar e Punir”, delineando novas concepções de ensino para o sujeito em desenvolvimento. Enaltecemos contrapontos em relação a esses mecanismos intrínsecos a um modelo de currículo tradicional, que segue e parametriza reflexos de práticas educativas que docilizam corpos - Foucault (1984). Em síntese, aportamos uma pesquisa qualitativa, de ordem bibliográfica com analogias reflexivas a um artigo científico, mediante levantamento da literatura -Google Acadêmico, consubstanciando autores como Freire (2007), Santos (2002), Hernández (1998) e Silva (2005), reverberando discussões assertivas sobre o método com projetos, com conjecturas de se pensar uma educação libertadora em um novo protótipo de sociedade, que eleve o sujeito em construção, não ao patamar de um soldado que segue em marcha, que controla ou é controlado por seu meio – “panóptico educativo”, mas, de um indivíduo que se projeta em seus espaços e transpassa o “quadriculamento pedagógico”, conduzindo-se por uma visão de currículo conectado com novas projeções sociais. Delineamos nos moldes conclusivos, tratativas da “caixa de ferramentas” na perspectiva de Foucault, enunciada mediante a essencialidade de se pensar o fazer docente para com o modelo de sociedade democrática, que investiga sua identidade em prol de mecanismos viabilizados por novas concepções históricas de um mundo humanizado, em construção.
PENGARUH PROMOSI MEDIA SOSIAL PRODUK LE MINERALE PT. FRESINDO JAYA TERHADAP NIAT BELI KONSUMEN
Authors: Janice Jesslyne Naomi , Bangsawan Satria , Rachmat Ramelan Mudji 
Published: November 2022

Abstrak
Penelitian ini bertujuan untuk mengetahui adakah pengaruh promosi media sosial terhadap niat beli pada konsumen Le Minerale di Kota Bandar Lampung. Metode pengumpulan data menggunakan kuesioner dengan skala likert yang telah disebar terhadap 100 responden. Alat analisis dalam penelitian ini menggunakan regresi linier sederhana dengan program SPSS 20. Hasil dari penelitian ini menunjukan bahwa variabel promosi media sosial berpengaruh positif dan signifikan terhadap niat beli konsumen. Saran penelitian ini adalah : (1) Perusahaan PT. Fresindo Jaya dapat meningkatkan promosi dengan cara melakukan bentuk pemahaman dan penawaran produk Le Minerale kepada konsumen dengan melakuakn edukasi seperti seminar online atau talkshow melalui media sosial resmi Le Minerale. (2) dapat melalukan kerjasama dengan pihak praktisi kesehatan ataupun public figure sebagai brand ambassador dalam upaya meningkatkan promosi melalui media sosial dalam meningkatkan upaya konsumen dalam niat beli produk Le Minerale.
PENGARUH KEPEMIMPINAN TRANSFORMASIONAL TERHADAP KINERJA DOSEN DI AKADEMI SEKRETARI DAN MANAJEMEN ARIYANTI
Authors: Rustiadi Rizzky 
Published: November 2022

ABSTRAK
Pengaruh Kepemimpinan Transformasional Terhadap Kinerja Dosen (Locus Penelitian pada Akademi Sekretari Dan Manajemen Ariyanti Kota Bandung). Penelitian ini dilakukan di Kampus Akademi Sekretari dan Manajemen Ariyanti Bandung. Dimana locus penelitian ini merupakan tempat penulis bekerja. Pada penelitian ini peneliti mencoba menggangkat sebuah penelitian yang dikaitkan dengan perkembangan teknologi pada saat ini. Perkembangan teknologi saat ini telah memasuki era revolusi industri dimana hampir semua aktivitas pekerjaan menggunakan akses digitalisasi. Sehubungan locus penelitian ini adalah bidang pendidikan peneliti mencoba menghubungkan era revolusi industri ini dikaitkan dengan bidang pendidikan. Metode penelitian yang digunakan adalah deskriptif analisis, dengan jumlah populasi sebanyak 50 orang dan semuanya dijadikan sebagai responden (Survey). Teknik analisis data yang digunakan adalah teknik analisis deskiptif. Adapun hasil penelitiannya adalah Kepemimpinan Transformasional di Akademi Sekretari dan Manajemen Ariyanti dikategorikan cukup baik. Kinerja dosen dikategorikan cukup baik. Hal ini terlihat dari kriteria ketercapaian skor sebesar 3.14.
Kata kunci : Pemimpin, Kepemimpinan Transformasional, Kinerja Dosen
PENGARUH BIAYA PRODUKSI TERHADAP LABA BERSIH PT PANAMA MEGAH JAYA BANDUNG PERIODE 2015-2019
Authors: Indrawan Bisma , Aqidhah Nurul 
Published: November 2022

ABSTRAK
Penelitian ini bertujuan untuk mengetahui besarnya pengaruh biaya produksi terhadap laba bersih PT Panama Megaha Jaya Bandung periode 2015-2019.
Metode yang digunakan dalam penelitian ini adalah kuantitatif, teknik pengumpulan data yang digunakan adalah studi pustaka, observasi, dan wawancara. Sedangkan analisis data menggunakan uji normalitas.
Berdasarkan hasil penelitian dapat ditarik kesimpulan bahwa variabel X (Biaya Produksi) dan Variabel (Y) memiliki hubungan korelasi tinggi sebesar 0,772 (pearson product moment). Hasil koefisien determinasi menunjukan bahwa biaya produksi berpengaruh hanya 59,6% terhadap laba bersih dan sisanya 40,4% dipengaruhi oleh faktor lain yang tidak diteliti oleh penulis. Untuk pengukuran uji-T, nilai t hitung 2.104 dan diperoleh t tabel sebesar 3.182, maka 2.104 < 3.182 Ho diterima dan Ha ditolak, berarti tidak terdapat pengaruh signifikan antara biaya poduksi terhadap laba bersih.
Permasalahan dalam penelitian ini adalah, pada tahun 2018 terjadi penurunan laba bersih sebesar 18%, apabila nilai mata uang dolar mengalami kenaikan dan nalai mata uang mengalami penurunan, dan ketidakstabilan kehadiran karyawan bagian produksi.
Upaya dalam mengatasi permasalahan tersebut adalah perusahaan harus meningkatkan volume produksinya dan meningkatkan jumlah penjualan. Untuk meningkatkan penjualan, dapat dilakukan dengan meningkatkan strategi pemasaran misalnya melalui pemasangan iklan, menciptakan inovasi terhadap produk, dan lain sebagainya. Lakukan selektif order dengan menggunakan minimal price. Buatlah lingkungan kerja yang nyaman, insentif bagi karyawan dengan kehadiran penuh.
Kata Kunci : Biaya Produksi, Laba Bersih
Factores que influyen en la percepción del alumnado sobre la importancia de la educación física
Authors: García Vélez Antonio Joaquín , Jiménez Parra José Francisco 
Published: November 2022

Currently, an increase in sedentary behaviors has been observed in young people due to changes in the motivations and interests of the students. For this reason, it was proposed to know the factors that influence the perception of students about the importance of Physical Education (PE). For this, there were 780 Primary and Secondary students from the Region of Murcia, who were administered the Attitudes towards PE Questionnaire (CAEF). Regarding the results, it was observed that the variables that mainly influence the perception of the importance of PE are the good relationship with the teacher of the area, the increase in mood after the classes and the belief that the contents are valuable. Therefore, it is concluded that PE must have a curriculum with valuable and useful content, establish a good classroom climate and use a methodology that encourages the perception of competence and belonging to the group.
Actualmente se ha observado un aumento de conductas sedentarias en los jóvenes debido a cambios en las motivaciones e intereses de los estudiantes. Por este motivo, se planteó conocer los factores que influyen en la percepción del alumnado sobre la importancia de la Educación Física (EF). Para ello, se contó con 780 estudiantes de Primaria y Secundaria de la Región de Murcia, a los que se les administró el Cuestionario de Actitudes hacia la EF (CAEF). En cuanto a los resultados, se observó que las variables que principalmente influyen en la percepción sobre la importancia de la EF son la buena relación con el docente del área, el aumento del estado de ánimo tras las clases y la creencia de que los contenidos son valiosos. Por lo tanto, se concluye que la EF debe tener un currículo con contenidos de valor y útiles, establecer un buen clima del aula y usar una metodología que fomente la percepción de competencia y de pertenencia al grupo.
Functional Properties of Noodles Analogue from Water Yam, Yellow Maize, and African Yam Bean Mixtures – A Response Surface Methodology
Authors: Kalu C. E. , Alaka I. C. , Asadu K. C. , OKpara K. C. , Daniel C. C. 
Published: November 2022

Response surface methodology was used to investigate the effect of extrusion process on proximate composition of noodles analogue from water yam, yellow maize, and African yam bean flour mixture. Flour blend from water yam, yellow maize, and African yam bean were produced and was used to extrude noodles analogue using a Brabender single screw laboratory extruder (Duisburg DCE 330 model) fitted with 3.0 mm die nozzle diameter. A central composite rotatable design (CCRD) with three variables, namely barrel temperature, feed moisture content and screw speed and five level coded – a, -1, 0, +1, +a, was used and data analyzed by regression analysis. Results showed that bulk density ranged from 0.41 to 0.09 g/cm water solubility index ranged from 4.41 to 6.36%; water absorption capacity ranged from 2.05 to 5.66% and expansion ratio ranged from 1.62 to 3.81respectively. The coefficients of determinations (R2) were high and ranged from 0.9039 to 0.9887 at 5% level. The response surface plots suggested that the models developed had a good fit and the CCRD was effective in explaining the effect of the process conditions on noodles analogue as influenced by barrel temperature, feed moisture content, and screw speed of the extruder. The data obtained from the study could be used for control of product characteristics. The study indicated that improved noodles analogue from available and cheap roots, cereal and legumes such as water yam, yellow maize, and African yam bean can be produced for possible projection for the commercial production of noodles analogue.
Climate Smart Agriculture with Drought Resistant Tomato (Solanum lycopersicum) Cultivars under Subtropical Climate
Authors: Nahar Kamrun , Ullah S. M. 
Published: November 2022

Climate smart agriculture focus on crop production under climate stress. Climate change adaptation potential was investigated in medium textured soil to evaluate the drought/water stress effect on different cultivars of tomato. The imposed stress levels were 82 -100% (T0), 69-85% (T1), 53-67% (T2) and 40-50% (T3) of the FC (Field Capacity). In water stressed condition no significant influence was observed in production of plant dry matter and increased acids & soluble sugars and consequently improved the fruit quality. Water stresses did not show any significant effect on height, yield and increased in BR-5, probably due to its tolerance to water stress.
Also, none of the stress- treated tomatoes showed deteriorated visual quality of the fruits and were red over 90%. No bruising and internal damages in tissues were detected due to stress. Water stresses enhanced the sweetness of the fruits by increasing their organic solute contents as glucose, fructose and sucrose contents and improved the quality by increasing the amount of important acids such as citric acid, malic acid and ascorbic acid, showed the adaptation responses of the crop to climatic stress due to conspicuous tendency of tomato plants to adjust osmotically against drought stress.
Assessment of Laparoscopic Spleen-Preserving Hilar Lymphadenectomy for Advanced Proximal Gastric Cancer Without Invasion Into the Greater Curvature
Authors: Lin Jian-Xian , Lin Jun-Peng , Wang Zu-Kai , Li Ping , Xie Jian-Wei , Wang Jia-Bin , Lu Jun , Chen Qi-Yue , Cao Long-Long , Lin Mi , Tu Ru-Hong , Lin Guang-Tan , Huang Ze-Ning , Lin Ju-Li , Zheng Hua-Long , Lin Guo-Sheng , Huang Chang-Ming , Zheng Chao-Hui 
Published: November 2022

ImportanceThe survival benefit of laparoscopic total gastrectomy combined with spleen-preserving splenic hilar lymphadenectomy (LSTG) for locally advanced proximal gastric cancer (APGC) without invasion into the greater curvature remains uncertain.ObjectiveTo compare the long-term and short-term efficacy of LSTG (D2 + No. 10 group) and conventional laparoscopic total gastrectomy (D2 group) for patients with APGC that has not invaded the greater curvature.Design, Setting, and ParticipantsIn this open-label, prospective randomized clinical trial, a total of 536 patients with clinical stage cT2 to 4a/N0 to 3/M0 APGC without invasion into the greater curvature were enrolled from January 2015 to October 2018. The final follow-up was on October 31, 2021. Data were analyzed from December 2021 to February 2022.InterventionsEligible patients were randomized to the D2 + No. 10 group or the D2 group.Main Outcomes and MeasuresThe primary outcome was 3-year disease-free survival (DFS). The secondary outcomes were 3-year overall survival (OS) and morbidity and mortality within 30 days after surgery.ResultsOf 526 included patients, 392 (74.5%) were men, and the mean (SD) age was 60.6 (9.6) years. A total of 263 patients were included in the D2 + No. 10 group, and 263 were included in the D2 group. The 3-year DFS was 70.3% (95% CI, 64.8-75.8) for the D2 + No. 10 group and 64.3% (95% CI, 58.4-70.2; P = .11) for the D2 group, and the 3-year OS in the D2 + No. 10 group was better than that in the D2 group (75.7% [95% CI, 70.6-80.8] vs 66.5% [95% CI, 60.8-72.2]; P = .02). Multivariate analysis revealed that splenic hilar lymphadenectomy was not an independent protective factor for DFS (hazard ratio [HR], 0.86; 95% CI, 0.63-1.16) or OS (HR, 0.81; 95% CI, 0.59-1.12). Stratification analysis showed that patients with advanced posterior gastric cancer in the D2 + No. 10 group had better 3-year DFS (92.9% vs 39.3%; P &amp;lt; .001) and OS (92.9% vs 42.9%; P &amp;lt; .001) than those in the D2 group. Multivariate analysis confirmed that patients with advanced posterior gastric cancer could have the survival benefit from No. 10 lymph node dissection (DFS: HR, 0.10; 95% CI, 0.02-0.46; OS: HR, 0.12; 95% CI, 0.03-0.52).Conclusions and RelevanceAlthough LSTG could not significantly improve the 3-year DFS of patients with APGC without invasion into the greater curvature, patients with APGC located posterior gastric wall may benefit from LSTG.Trial RegistrationClinicalTrials.gov Identifier: NCT02333721
Photopolymerization, Free Radical
Authors: Allonas Xavier , Croutxé‐Barghorn Céline , Ley Christian , Schuller Anne‐Sophie 
Published: November 2022

AbstractThis study presents the main principles of the free radical photopolymerization reaction. Photoinitiators and photoinitiating systems are reviewed, and their most important features are discussed. Attention is paid to sources of light, particularly light‐emitting diodes (LEDs), which are discussed with respect to the absorption properties of commercially available photoinitiators (PI). The mechanism of free radical photopolymerization is also reviewed, with a focus on simulation models. Characterization techniques are described, demonstrating that the final properties can be analyzed, as well as the polymerization process and side effects such as oxygen inhibition. Finally, the different families of monomers usable in free‐radical photopolymerization are presented, together with the main properties of the corresponding photopolymers.
FAR‐sighted conservation
Authors: Thomas Chris D. , Hill Jane K. , Ward Caroline , Hatfield Jack H. 
Published: November 2022

Abstract
Conservation targets that reference historical expectations, such as maintaining specified areas of intact ecosystems, restoring degraded ones or maintaining the historic distributions of species, may not be realistic in the context of ongoing environmental change, whereas targets that aspire to accommodate the complex realities of the human‐altered and changing world tend to be too vague to implement.
Using the first three recently proposed Convention on Biological Diversity post‐2020 global biodiversity Action Targets as context, we suggest a policy framework that evaluates how we might shift from an emphasis on resisting sometimes inevitable change to the development of positive directions of change for people and biodiversity. Our Anthropocene approach builds on the fact that all ecosystems have already been shaped by interactions with people and that ongoing change is inevitable.
We outline a Facilitate–Accept–Resist (FAR) framework for all levels of conservation decision‐making and actions, ranging from overall conservation strategies (planning, setting targets, monitoring change, selecting indicators) to the conservation of places (sites, ecosystems, landscapes) and species, and to the provision of ecosystem services and human well‐being. For each potential decision, the approach evaluates whether, for whom and how one might facilitate, accept or resist particular changes. We highlight the value of inclusive engagement in the process to ensure that benefits from biodiversity are equitably shared.
The CBD Action targets reflect tensions between maintaining historic states of nature and the Anthropocene reality of integrating people with nature and accepting change. The challenge is to operationalize the inclusivity, integration and change elements of the targets whilst not ‘abandoning’ locations that many conservationists consider to be key places for wildlife. The FAR framework represents a way to operationalize decision‐making in the face of this tension, so that the facilitation and acceptance of positive biodiversity change is adopted at least as frequently as change is resisted.
Topological Insulator Optoelectronic Synapses for High‐Accuracy Binary Image Recognition using Recurrent Neural Networks
Authors: Wan Zhengfen , Zhang Qiwen , Hu Fangzhen , Dong Yibo , Li Runze , Hu Liangchen , Xie Yiyang , Yue Zengji , Chen Xi , Gu Min 
Published: November 2022

AbstractArtificial optoelectronic synapses have drawn tremendous attention in neuromorphic computing due to their exceptional properties of incorporating optical‐sensing and synaptic functions. However, the complex fabrication processes and device architectures greatly limit their applications. More importantly, artificial neural networks (ANNs) commonly implemented with optoelectronic synapses cannot take full advantage of the time‐dependent data of synaptic devices, resulting in defective accuracies. Here, facile two‐terminal optoelectronic synapses based on topological insulator Sb2Te3 films are fabricated, which exhibit significant photocurrent responses, owing to the efficient light‐matter interaction in bulk and the topological surface state of Sb2Te3. The performance of Sb2Te3 devices can be tuned both optically and electrically. Typical characteristics of synapses, such as paired‐pulse facilitation, short‐term memory, long‐term memory, and learning behavior, have been demonstrated. With the establishment of recurrent neural networks (RNNs) that are committed to processing temporal data, the as‐fabricated synapse devices are employed for binary image recognition of handwritten numbers “0” and “1”. The recognition accuracy of RNNs can reach as high as 100%, which is dramatically higher than those of ANNs. The effective employment of temporal data with RNNs ensured high recognition accuracy. These Sb2Te3 optoelectronic synapses with RNNs indicate the great potential for developing high‐performance brain‐inspired neuromorphic computing.
HPV Enhances HNSCC Chemosensitization by Inhibiting SERPINB3 Expression to Disrupt the Fanconi Anemia Pathway
Authors: Huang Zixian , Chen Yongju , Chen Rui , Zhou Bin , Wang Yongqiang , Hong Lei , Wang Yuepeng , Wang Jianguang , Xu Xiaoding , Huang Zhiquan , Chen Weiliang 
Published: November 2022

AbstractHead and neck squamous cell carcinoma (HNSCC) is the most common malignant tumor of the head and neck, and the prognosis of patients is poor due to chemotherapeutic resistance. Interestingly, patients with HNSCC induced by human papillomavirus (HPV) infection are more sensitive to chemotherapy and display a better prognosis than HPV‐negative patients. The biological relevance of HPV infection and the mechanism underlying chemosensitivity to cisplatin remain unknown. Herein, SERPINB3 is identified as an important target for regulation of cisplatin sensitivity by HPV‐E6/E7 in HNSCC. Downregulation of SERPINB3 inhibits cisplatin‐induced DNA damage repair and enhances the cytotoxicity of cisplatin. In detail, decreasing SERPINB3 expression reduces the USP1‐mediated deubiquitination of FANCD2–FANCI in the Fanconi anemia pathway, thereby interfering with cisplatin‐induced DNA interstrand crosslinks repair and further contributing to HNSCC cell apoptosis. To translate this finding, pH‐responsive nanoparticles are used to deliver SERPINB3 small interfering RNA in combination with cisplatin, and this treatment successfully reverses cisplatin chemotherapeutic resistance in a patient‐derived xenograft model from HPV‐negative HNSCC. Taken together, these findings suggest that targeting SERPINB3 based on HPV‐positive HNSCC is a potential strategy to overcome cisplatin resistance in HPV‐negative HNSCC and improves the prognosis of this disease.