bluuebunny/crossref_metadata_2025_split huggingface dataset:
Working conditions and health status of elderly teaching staff (a review)
Authors: Anishchenko E. B. , Trankovskaya L. V. , Vazhenina A. A. , Tarasenko G. A. , Kovalchuk V. K. 
Published: September 2022

This article reviews literature data on the working conditions, labor organization, health and psycho-emotional status, performance, and age composition of teaching staff. Population ageing is a global trend, primarily associated with increased life expectancy and decreased fertility rates. The reviewed publications note a steady increase in the number of elderly people employed in educational institutions of various levels. According to hygienic assessments, the working conditions of teaching staff can be distinguished as potentially harmful. High working, mental, emotional, and voice loads were found to be the key factors affecting teachers’ health, performance, and professional longevity. The accelerating pace of life, growing volumes of circulating information, spreading digitalization and robotization, adoption of online educational technologies – all these phenomena impose an additional psychological burden on teachers, elderly people in particular, becoming a source of distress and neuroticism. At the same time, the involvement of elderly people in intellectually stimulating professional activities and the respective adequate payment were shown to have a positive effect on the preservation of their cognitive functions and overall quality of life. These findings determine the relevance of investigating the occupational hygiene of elderly teaching staff in order to develop measures aimed at preserving their health, quality of life, and professional longevity.
Role of neuroproteins in retinal neurodegeneration in diabetic retinopathy
Authors: Ruchkin M. P. , Markelova E. V. , Fedyashev G. A. 
Published: September 2022

Aim. To evaluate the serum levels of S100b protein, brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF) in patients with type 2 diabetes mellitus, as well as to establish a correlation between the studied parameters and retinal neurodegeneration.Methods. In total, 80 patients with confirmed type 2 diabetes (experimental group) and 30 healthy volunteers (control group) were included in the study. All patients were examined using an RTVue-100 optic coherence tomography scanner (Optovue, USA) and a MAIA microperimeter (CenterVue, Italy). The serum levels of S100b, BDNF, and NGF were determined by a sandwich-type solid-phase enzyme immunoassay using reagents produced by R&D Diagnostics Inc. (USA).Results. The serum level of S100b protein was found to be significantly (p = 0.001) higher in the experimental group, comprising 56.86 (31,12–104,02) pg/ml, compared to that in the control group of 45.19 (37.27–51.79) pg/ml. Conversely, the brain-derived neurotrophic factor (BDNF) showed a significant (p = 0.02) decrease to the level of 27.38 (25.15–29.12) pg/ml in the experimental group compared to the level of 30.19 (27.38–32.14) pg/ml in the control group. The serum level of nerve growth factor (NGF) in the experimental group was found to be 7.53 (5.63–10.54) pg/ml, thereby exceeding significantly (p = 0.02) the level of 5.96 (4.77–8.13) pg/ml in the control group.Conclusions. The results obtained indicate an imbalance in the serum levels of the studied neuroproteins in patients with type 2 diabetes mellitus and retinal neurodegeneration signs. The identified variations require further research in order to determine the feasibility of their use as additional criteria for predicting the development of retinal neurodegeneration in such patients.
Application of biologically active substances from marine hydrobionts in the treatment of age-related macular degeneration
Authors: Kryzhanovskiy S. P. , Pestryakova Ya. F. , Bogdanovich L. N. , Ustyugova S. O. 
Published: September 2022

Aim. To evaluate the effectiveness of products obtained from marine aquatic organisms in the treatment of age-related macular degeneration (AMD).Methods. In total, 90 patients diagnosed with AMD of various stages were examined. The control group (30 people) received a vitamin-mineral complex containing carotenoids – lutein and zeaxanthin (Retinorm). The 2nd group of patients (30 people) received the Scallop Extract product. The 3rd group of patients (30 people) received the Ascidia Oil Extract in combination with the basic therapy. All patients underwent a comprehensive ophthalmological examination, including optical coherence tomography of the macula and perimetry. The examination was carried out prior to and two weeks after treatment completion.Results. The experimental group of patients receiving Scallop Extract showed a significant increase in visual acuity indicators after treatment completion. For comparison, the experimental groups of patients receiving Ascidia Oil Extract demonstrated improved photosensitivity indicators and reduced visual field defects.Conclusions. Addition of marine hydrobiont-based products to the basic AMD therapy is pathogenetically justified due to its positive effects on the maintenance and improvement of visual functions, as well as the light sensitivity of the retina.
Optimization of corticosteroid therapy for uveitis complicated with macular edema
Authors: Emanova L. P. , Kolenko O. V. , Danilova L. P. , Povalyaeva D. A. , Zhayvoronok N. S. , Gokhua T. I. 
Published: September 2022

Aim. To develop a therapeutic strategy for uveitis complicated with macular edema (ME) based on topical corticosteroids (CS), including sub-Tenon’s administration of CS with subsequent intravitreal injection an Ozurdex implant.Methods. The examination of 32 patients with chronic recurrent uveitis complicated with ME revealed a correlation between uveitis and the presence of systemic diseases (ankylosing spondylitis, rheumatoid arthritis, etc.). The patients were divided into two groups depending on the selected treatment after completion of the sub-Tenon’s administration of dexamethasone: 1st group – 17 patients with Ozurdex intravitreal implants; 2nd group – 15 patients receiving only dexamethasone instillations. Ophthalmological examination was carried out using optical coherence tomography and microperimetry. The markers of eye inflammation included the total clinical inflammation index and C-reactive protein (CRP) levels in lacrimal fluid (LF). The patients were examined prior to treatment as well as 10 days, 1, 3, 6, and 12 months after the completion of CS therapy. The control comprised functionalmorphological and laboratory parameters of 10 healthy people.Results. The main intragroup differences were observed one month after the onset of treatment. Patients in the 1st group demonstrated the disappearance of clinical symptoms of uveal inflammation, with the CRP level in LF returning to normal (5.3 ± 0.07 mg/ml) values and differing insignificantly from the control. In these patients, the largest increase in functional parameters compared to the baseline was recorded, with the best corrected visual acuity (BCVA) and eye illumination sensitivity growing by 0.59 and 5.8 dB, respectively. Patients in the 2nd group demonstrated the persistence of some clinical symptoms of uveal inflammation. In these patients, optimal functional and morphological results were achieved three months after the onset of treatment. These results were not only inferior to those obtained in the 1st group, but also proved unstable over longer follow-up periods (6–12 months).Conclusions. The developed optimized approach of CS therapy for uveitis complicated with ME confirmed its high clinical efficacy: a 3-fold reduction in the duration of uveal inflammation symptoms, a 1.25-fold increase in the frequency of complete ME resorption with the restoration of normal retinal topography in the macula, as well as a 2.2- and 2.35-fold increase in BCVA and eye illumination sensitivity, respectively.
Determination of the anthocyanine profile and optimal parameters of their extraction from <I>Empetrum nigrum</I> fruits
Authors: Ponomarchuk S. G. , Salikova A. A. , Plaksen N. V. , Ustinova L. V. , Grigorchuk V. P. 
Published: September 2022

Aim. To determine the profile of anthocyanins and optimal parameters of their extraction from Empetrum nigrum fruits.Materials and methods. Anthocyanins contained in the dried fruits of Empetrum nigrum were identified using HPLC and mass spectrometry. The anthocyanin content was determined using differential spectrophotometry.Results. Empetrum nigrum fruits were found to contain the following substances: delphinidin, cyanidin, petuinidin, peonidin, and malvidin. The main anthocyanins comprised cyanidin-3-galactose (33.068%), delphinidin-3-galactose (21.733%), and malvidin-3-galactose (15.374%). The necessary conditions for the maximum extraction of anthocyanins from Empetrum nigrum fruits were established to be as follows: the use of 70% ethyl alcohol containing hydrochloric acid as an extrant; a sample weight of 1.0 g; a particle size of 1.0 mm; the 1:70 ratio of raw materials and extractant; an extraction time of 90 min.Conclusions. The Empetrum nigrum fruits grown in the Kamchatka region were found to contain eight anthocyanins were identified. The anthocyanin content comprised 5.65 ± 0.04%.
Shape Modeling of Dimorphos for the Double Asteroid Redirection Test (DART)
Authors: Terik Daly R. , Ernst Carolyn M. , Barnouin Olivier S. , Gaskell Robert W. , Palmer Eric E. , Nair Hari , Espiritu Ray C. , Hasnain Sarah , Waller Dany , Stickle Angela M. , Nolan Michael C. , Trigo-Rodríguez Josep M. , Dotto Elisabetta , Lucchetti Alice , Pajola Maurizio , Ieva Simone , Michel Patrick 
Published: September 2022

Abstract
The Double Asteroid Redirection Test (DART) is the first planetary defense test mission. It will demonstrate the kinetic impactor technique by intentionally colliding the DART spacecraft with the near-Earth asteroid Dimorphos. The main DART spacecraft is accompanied by the Italian Space Agency Light Italian CubeSat for Imaging of Asteroids (LICIACube). Shape modeling efforts will estimate the volume of Dimorphos and constrain the nature of the impact site. The DART mission uses stereophotoclinometry (SPC) as its primary shape modeling technique. DART is essentially a worst-case scenario for any image-based shape modeling approach because images taken by the camera on board the DART spacecraft, called the Didymos Reconnaissance and Asteroid Camera for Optical navigation (DRACO), possess little stereo and no lighting variation; they simply zoom in on the asteroid. LICIACube images add some stereo, but the images are substantially lower in resolution than the DRACO images. Despite the far-from-optimal imaging conditions, our tests indicate that we can identify the impact site to an accuracy and precision better than 10% the size of the spacecraft core, estimate the volume of Dimorphos to better than 25%, and measure tilts at the impact site over the scale of the spacecraft with an accuracy better than 7°. In short, we will know with excellent accuracy where the DART spacecraft hit, with reasonable knowledge of local tilt, and determine the volume well enough that uncertainties in the density of Dimorphos will be comparable to or dominate the uncertainty in the estimated mass. The tests reported here demonstrate that SPC is a robust technique for shape modeling, even with suboptimal images.
Chemical composition and thermal properties of Tunisian pecan nut [Carya illinoinensis (Wangenh.) K. Koch] oils
Authors: Bouali I. , Rattouli H. , Herchi W. , Martine L. , Grégoire S. , Albouchi A. , Martínez-Force E. , Boukhchina S. , Berdeaux O. 
Published: September 2022

An investigation on fatty acid, triacylglycerol, tocopherol, and xanthophyll contents and thermal properties of pecan (Carya illinoinensis) kernel oils from two cultivars was carried out. The main fatty acids were oleic acid, followed by linoleic and palmitic acids. The predominant triacylglycerols were OOL, OOO, and OLL (where O stands for oleoyl and L for linoleoyl). Pecan kernel oil is a rich source of tocopherols, mainly γ-tocopherol. Two xanthophylls (lutein and zeaxanthin) were investigated, and lutein was found to be the major one. Thermal behavior was studied by differential scanning calorimetry (DSC). Pecan nut oil displayed melting and crystallization transitions at low-temperature zones. The difference between DSC parameter values provides a path for distinguishing among cultivars. These data promote pecan kernel oil as a potential source of bioactive compounds with nutraceutical properties (monounsaturated fatty acids, tocopherols, and xanthophylls) and reveal, for the first time, the thermal properties of Carya illinoinensis oil.
PELATIHAN TRIK CARA CEPAT MENJAWAB SOAL SBMPTN
Authors: Simamora Yumira , Matondang Khoiruddin , Bella Risna Mira , Siswadi Siswadi 
Published: September 2022

Ujian Tulis Berbasis Komputer (UTBK) wajib diikuti bagi siswa yang ingin ingin masuk ke perguruan tinggi negeri dengan jalur SBMPTN. Tujuan kegiatan ini adalah memberikan pemahaman kepada siswa kelas XII trik cara cepat menjawab soal UTBK jalur SBMPTN. Sedangkan tujuan tujuan UTBK adalah memprediksi calon mahasiswa dalam menyelesaikan kuliah di kampus yang dipihnya dengan baik dan tepat waktu. Dengan demikian siswa kelas XII penting dan perlu mempersiapkan diri dan mengetahui trik atau cara cepat menyelesaikan soal UTBK matematika. Kegiatan pengabdian ini dilaksanakan di Madrasah Aliyah Laboratorium IAIN Medan pada tanggal 18 November 2021. Sasaran dari kegiatan ini adalah siswa kelas XII dan XII MIPA A dan B sejumlah 69 siswa. Materi yang disampaikan adalah Limit Fungsi ALjabar dan Perbandingan. Berdasarkan hasil evaluasi, target utama dari pelaksanaan kegiatan ini telah tercapai. Siswa mengetahui cara trik atau cara cepat, 81% siswa mampu mengerjakan soal Limit fungsi Aljabar, dan Perbandingan dengan cepat, benar dan baik.
Voorwaardelijke beëindiging van levenslang in Caribisch Nederland
Authors: Pesselse G. 
Published: September 2022

Voorwaardelijke beëindiging van levenslang in Caribisch Nederland
In alle vijf de zaken stelt het Gemeenschappelijk Hof voorop dat beoordeeld moet worden of verdere onvoorwaardelijke tenuitvoerlegging van de levenslange gevangenisstraf geen redelijk doel meer dient. Dat centrale criterium sluit aan bij de wettekst en het kader van het EHRM. Het EHRM specificeert zelfs dat legitieme strafdoelen onder meer inhouden ‘punishment, deterrence, public protection and rehabilitation’. Tegen die achtergrond is opvallend dat in alle zaken wordt overwogen dat, gelet op de strafmotivering van de betreffende veroordelingen, ‘het’ doel van de opgelegde straf was om de maatschappij te beschermen tegen recidive van de veroordeelde (niet: het primaire, het belangrijkste).
De strijd om slachtofferschap
Authors: Daems Tom , Pemberton Antony , van Stokkom Bas 
Published: September 2022

The struggle for victimhood – An introduction
In recent decades victims of crime have been receiving a lot of attention in science and policy. It gave rise to the development and flourishing of a separate discipline, victimology. The emphasis was on mapping victimization and fear of crime, the consequences of victimization, the development and evaluation of victim support, victims’ rights and newer forms of conflict resolution (e.g. restorative justice). Much victimological research was – and still is – focused on policy and improving the plight of victims of crime. However, more recently, we have seen a growing interest in studying victimization in a broader, societal context. This is done inter alia under the banner of a cultural victimology and in the wake of studies into processes of transitional justice, but also in the context of a socially critical debate about an alleged culture of victimization, therapy or complaint. It is such perspectives on victims and victimization that are at the center of this special issue on ‘cultures of victimhood’. The introductory article identifies and discusses some of the main developments and issues in this area of research and debate.
Plaatsen van terreur, mensenrechten en nationale identiteit
Authors: van Vree Frank 
Published: September 2022

Places of terror, human rights and national identity
This essay analyses the global rise and various meanings of musealised prisons and torture centres. As sites of memory, they refer to painful, often gruesome episodes from the past. They use the same museum grammar, the roots of which can be traced back to the musealisation of Nazi concentration and extermination camps, in particular Majdanek at the end of the Second World War. Further research shows that despite the similarities in form, the meaning of all these memorial sites may vary widely. In a country like Argentina, these sites of terror are primarily symbols of crimes against humanity and human rights violations, while in the Baltic States and Hungary, among others, they primarily refer to a national victimhood; as theatres of remembrance, they are a source of national identity. The study of such places can give us a lot of insight into the political relations within, but also between countries.
Polish Achievements in Bioactive Compound Production From In Vitro Plant Cultures
Authors: Pietrosiuk Agnieszka , Budzianowska Anna , Budzianowski Jaromir , Ekiert Halina , Jeziorek Małgorzata , Kawiak Anna , Kikowska Małgorzata , Krauze-Baranowska Mirosława , Królicka Aleksandra , Kuźma Łukasz , Łuczkiewicz Maria , Malarz Janusz , Matkowski Adam , Stojakowska Anna , Sykłowska-Baranek Katarzyna , Szopa Agnieszka , Szypuła Wojciech , Thiem Barbara , Zielińska Sylwia 
Published: September 2022

AbstractPlant cell and organ cultures are potential sources of valuable secondary metabolites that can be used as food additives, nutraceuticals, cosmeceuticals, and pharmaceuticals. Phytochemical biosynthesis in various in vitro plant cultures, in contrast to that in planta, is independent of environmental conditions and free from quality fluctuations.Pharmaceutical application of plant biotechnology is of interest to almost all departments of the Faculty of Pharmacy and Institute of Pharmacology in Poland with a botanical profile (Pharmaceutical Botany, Pharmacognosy, and Pharmacology).This study discusses the advances in plant biotechnology for the production of known metabolites and/or biosynthesis of novel compounds in plant cell and organ in vitro cultures in several scientific centers in Poland.
Semi-field evaluation of human landing catches versus human double net trap for estimating human biting rate of Anopheles minimus and Anopheles harrisoni in Thailand
Authors: Yan Chanly , Hii Jeffrey , Ngoen-Klan Ratchadawan , Saeung Manop , Chareonviriyaphap Theeraphap 
Published: September 2022

Background
Whilst the human landing catch (HLC) technique is considered the ‘gold standard’ for estimating human-biting rates, it is labor-intensive and fraught with potential risk of exposure to infectious mosquito bites. This study evaluated the feasibility and performance of an alternative method, the human double net trap (HDNT) relative to HLC for monitoring host-seeking malaria vectors of the Anopheles minimus complex in a semi-field system (SFS).

Methods
HDNT and HLC were positioned in two rooms, 30 m apart at both ends of the SFS. Two human volunteers were rotated between both traps and collected released mosquitoes (n = 100) from 6:00 pm till 6:00 am. Differences in Anopheles mosquito densities among the trapping methods were compared using a generalized linear model based on a negative binomial distribution.

Results
There were 82.80% (2,136/2,580) of recaptures of wild-caught and 94.50% (2,835/3,000) of laboratory-reared mosquitoes that were molecularly identified as An. harrisoni and An. minimus, respectively. Mean density of An. harrisoni was significantly lower in HNDT (15.50 per night, 95% CI [12.48–18.52]) relative to HLC (25.32 per night (95% CI [22.28–28.36]), p < 0.001). Similarly, the mean density of a laboratory strain of An. minimus recaptured in HDNT was significantly lower (37.87 per night, 95% CI [34.62–41.11]) relative to HLC (56.40 per night, 95% CI [55.37–57.43]), p < 0.001. Relative sampling efficiency analysis showed that HLC was the more efficient trap in collecting the An. minimus complex in the SFS.

Conclusion
HDNT caught proportionately fewer An. minimus complex than HLC. HDNT was not sensitive nor significantly correlated with HLC, suggesting that it is not an alternative method to HLC.
Floral ontogeny of Tachigali (Caesalpinioideae, Fabaceae) species
Authors: Marques Casanova Jamile , Cardoso Domingos , Barros Claudia Franca , de Lima Haroldo Cavalcante , De Toni Karen L.G. 
Published: September 2022

Background
The present ontogenetic study reveals variations throughout floral development in three morphologically representative species from the genus Tachigali, allowing a better understanding of floral organs diversity, flower symmetry and their homologies, especially in Fabaceae, a diverse family that exhibits a wide variation in floral architecture. Tachigali (Caesalpinioideae) corresponds to an important Neotropical legumes tree genus with 58 species in Brazil. Species of the genus Sclerolobium Vogel were incorporated in its circumscription, increasing the diversity of its floral morphology.

Methods
This work aims to perform an ontogenetic study of T. denudata, T. paratyensis and T. spathulipetala, morphologically representative species of Tachigali, in order to describe the floral development and to better comprehend the floral morphology varieties among the species, using scanning electron microscopy.

Results
We found the studied species to have floral buds with acropetal and helical development along the inflorescence axis; sepals and petals with helical development, varying the position of the primordia in the bud, according to the different species; stamens with unilateral development and carpel with adaxial curvature. These data correspond to original records of Tachigali ontogeny and contribute to an improved understanding of floral morphology and symmetry with data related to the zygomorphic and early development of the sepals and petals.
The Effect of Promotional Format, Message Framing, and Psychological Distance on Perception and Engagement of Cause-related Marketing
Authors: Lii Yuan-Shuh , Ding May-Ching , Yang Alan Chin-Chien 
Published: September 2022

Aims: This research provides a unique lens by offering a more comprehensive consideration of cause-related marketing (CRM) campaign effectiveness. Specifically, we propose that the relative effectiveness of contribution type (monetary vs. in-kind) may hinge upon message framing (loss vs. gain-framed).
Study Design: Integrating construal level and prospect theories with related CRM, message framing, and psychological distance literatures lead to propositions.
Methodology: Literature reviews were first conducted. Rationalized on the construal level theory, multiple propositions of the effect of psychological distance on different contribution types and message framing are presented. The relationships among these concepts are proposed to have significant and positive effects on the effectiveness of CRM promotional campaigns based on the literature reviewed.
Conclusion: The proposed research model not only advances the collective knowledge of construal level theory and psychological distance literatures, making a theoretical contribution specifically in the CRM field, but also should provide important marketing insights to guide CRM practices.