bluuebunny/crossref_metadata_2025_split huggingface dataset:
Industrialiser la méthanisation agricole. Les reconfigurations d’une filière soumise aux exigences de production et de rentabilité
Authors: Bouzin Antoine 
Published: February 2025

On observe au cours des années 2010 une transformation du cadrage des politiques publiques afférentes à la méthanisation. En effet, le plan Énergie Méthanisation Autonomie Azote coporté en 2013 par les ministères de l’Agriculture et de l’Écologie présente la méthanisation comme une solution à divers problèmes publics – énergétique, climatique, traitement des déchets, économique, agro-environnemental – et désigne les mondes agricoles pour conduire la filière. On observe néanmoins à la fin des années 2010 un resserrement des attentes de l’État autour des enjeux énergie-climat. La priorité accordée à la production d’énergie est couplée à d’autres attentes d’ordre budgétaire impliquant des exigences en termes d’industrialisation et de rentabilité, soit en définitive un référentiel congruent avec les principes de la modernisation écologique. En outre, la diffusion des modèles de méthanisation en injection et la diminution des tarifs d’achat entérinée en 2020 tendent à imposer un nouveau modèle économique pour la filière. Si l’augmentation des coûts d’investissement complique l’accès des mondes agricoles à la filière, les industriels de l’énergie manifestent a contrario leur volonté d’intégrer le secteur et affichent des objectifs de production conséquents. C’est à la fois la définition des modèles légitimes de méthanisation et l’image de la filière elle-même, de son rôle dans la société, qui font l’objet d’une lutte cristallisée par la double concurrence d’une part entre les unités en cogénération et en injection, et d’autre part entre les unités agricoles et les unités centralisées.
Evaluation of the immunohistochemical expression of Nrf2, galectin-3, and CK19 in papillary thyroid carcinoma and its mimics
Authors: Abouelfadl Dalia M. , Shabana Marwa E. , Soliman Ahmed S.A. , Yassen Noha N. 
Published: February 2025

Background
The increasing incidence of papillary thyroid carcinoma (PTC) and inadequacy of routine histological examination in diagnosis and differentiation from its mimics necessitate the application of immunohistochemistry to deal with this issue. This study aimed to investigate the immunohistochemical expression of nuclear factor erythroid 2-related factor 2 (Nrf2), galectin-3, and cytokeratin-19 (CK19) in PTC and its mimics.

Patients and methods
This laboratory observational study was performed on 60 cases of neoplastic and nonneoplastic tissue with a diagnosis of PTC, papillary thyroid hyperplasia, and noninvasive follicular neoplasm with papillary-like features (NIFTP). Nrf2, galectin-3, and CK19 immunohistochemistry markers were used on tissue samples. Immunohistochemical markers expression was evaluated by quantitative method as negative, weak positive, moderate positive, and strong positive. The data were documented in a Microsoft Excel sheet and analyzed using SPSS 22 version software.

Result
Thirty-six cases each were PTC; 20 of them were classical PTC (CVPTC), and 16 were follicular PTC (FVPTC). Also, of the 24 nonneoplastic cases, nine cases were diagnosed as papillary hyperplasia cases, and eight cases were NIFTP. There was a statistically significant (P<0.0001) association of Nrf2 expression between PTC, papillary hyperplasia, and NIFTP. Also, there was a statistically significant (P<0.001) association between Nrf2 CVPTC and FVPTC. Our result showed that galectin-3 expression had a statistically significant association (P=0.0132) between PTC, papillary hyperplasia, and NIFTP. There was no statistically significant association (P=0.8907) between CK19 expression and PTC, papillary hyperplasia, or NIFTP. Nevertheless, CK19 expression had a statistically significant correlation (P=0.0492) between FVPTC and CVPTC. Nrf2 has the highest specificity and sensitivity compared to galectin-3 and CK19.

Conclusion
Using a panel of Nrf2, galectin-3, and CK19 has a useful role in PTC diagnosis and differentiation from its mimics. The most sensitive marker is Nrf2, then galectin-3, and finally CK19. It is better to use them together in identifying PTC.
Safety and efficacy of micropulse in pediatric eyes with refractory glaucoma
Authors: Sivasubramanian Raajaraajeshwari , Siddharth Kumar , Senthilkumar Vijayalakshmi A , Mani Iswarya , Rajendrababu Sharmila 
Published: February 2025

Purpose:
To analyze the safety and efficacy of micropulse transscleral cyclophotocoagulation (MP-TSCPC) in pediatric eyes with refractory glaucoma.

Design:
Hospital-based prospective interventional study.

Methods:
Patients less than 18 years of age, receiving MP-TSCPC between December 1, 2022 and May 31, 2023 with at least three follow-ups within 6 months period, were included in the study. Post-laser evaluation was done at day 1, 1 month, 3 months, and 6 months. Success outcomes were calculated at 1, 3, and 6 months follow-up.

Results:
A total of 23 eyes of 23 patients were included in the study. Mean intraocular pressure (IOP) lowering agents (P = 0.041) had significant change compared to the baseline value; however, the change was insignificant when eyes requiring additional IOP-lowering surgeries during the follow-up period were excluded. There was a significant reduction in IOP at each follow-up visit compared to the baseline (P = 0.000014). Two (8.6%) eyes required additional intervention within 1-month follow-up, another six eyes (26%) between 1–3 months, and three eyes (13%) between 3–6 months of MP-TSCPC. Total success was highest at 56.5% (13 eyes) at 1-month follow-up and at least 34.7% (8 eyes) at 6-month follow-up. No major complications were reported in our study.

Conclusion:
MP-TSCPC was found to be safe and effective in pediatric population. However, we observed a gradual reduction in the success with time, and thus, it can be individualized to patients with high risk for incisional surgery or those requiring immediate IOP reduction.
Modulation of Cardiovascular Parameters and Functional Capacity After Telephysiotherapeutic Breathing Yogic Pranayam in Young Vapers in India
Authors: Kaur Dilpreet , Rai Richa Hirendra , Malik Sameer , Kalra Sheetal , Chahal Aksh , Sidiq Mohammad , Sawant Komal Umesh , Dharmasya Aaditya Singh 
Published: February 2025

ABSTRACT

Introduction:
One of the global concerns regarding use of electronic nicotine delivery systems (ENDS) among young adults is like another pandemic which has caused associated lung injuries and cardiogenic effects on human body. Even though the product is not approved by FDA and is also banned in India, the rapid evolution of ENDS has led to an urgent need to study the prevalence of these products and its effect on the different cardiovascular parameters.

Methodology:
Thirty-four subjects, who endorsed use of vapes with nicotine containing liquids since last 2 months for alternate days a week and a minimum of 25 min a day, were assessed for their blood pressure, heart rate, double product, and 6MWD. It was ensured that they were “low dependence” as on the Penn State E-Cigarette Dependence Index (PSECDI) and also scored less than 10 on Beck Depression Inventory (BDI). They were then subjected to breathing exercise intervention for 28 sessions every day for 20 min. The observed mean values of all parameters were compared pre and postintervention for vapers.

Results:
There was statistically significant change in blood pressure, heart rate, double product but not in 6MWD after the breathing exercise intervention. At baseline, both groups had similar demographic profile; however, the control group had significantly different and better cardiovascular parameters than the ones who vaped.

Conclusion:
There was statistically significant improvement in the cardiovascular parameters in vapers after telephysiotherapeutic pranayam intervention in vapers.
Enlargeable foliations and the monodromy groupoid
Authors: Su Guangxiang , Yi Zelin 
Published: February 2025

Let

M

be a closed spin manifold, the Dirac operator with coefficient in the universal flat Hilbert

C^{\ast} \pi_{1}

-module determines a Rosenberg index element which, according to B. Hanke and T. Schick, subsumes the enlargeability obstruction of positive scalar curvature on

M

. In this paper, we generalize this result to the case of spin foliation. More precisely, given a foliation

(M,F)

with

F

spin, we will define a foliation version of Rosenberg index element and prove that it is nonzero in the presence of enlargeability of

(M,F)

. As a consequence, the foliation version of Rosenberg index element subsumes the enlargeability obstruction to the existence of leafwise positive scalar curvature metric.
Gestão financeira do empreendimento odontológico: perfil e atuação de cirurgiões–dentistas
Authors: LOLLI LUIZ FERNANDO , GRADELLA CESAR AUGUSTO NAGI , LOLLI MARIA CAROLINA GOBBI DOS SANTOS , MARSON GABIANO CARLOS , FREITAS KARINA MARIA SALVATORE 
Published: February 2025

O bom desenvolvimento gestor representa um dos fatoresindispensáveis para o sucesso profissional. Este trabalho objetivouinvestigar a gestão financeira adotada por profissionais de Odontologiaem associação ao perfil profissional. Representa estudo preliminar denatureza transversal, observacional, quantitativo, desenvolvido porentrevista estruturada. Foram consideradas variáveis de “perfilprofissional” e variáveis de “gestão”. O perfil profissional predominantefoi idade acima de 40 anos, gênero masculino, especialistas, com tempode formação de 0 a 10 anos, atuando como pessoa física, sem atenderconvênio. Com relação à gestão, predominaram profissionais que nãomantém sociedade, não cobram primeira consulta, consideram acomplexidade do tratamento para cobrar honorários, calculam a margemde lucro pelo tipo de trabalho realizado, desconhecem o custo da horaclínica, acreditam que o consultório é uma empresa, são responsáveispela gestão do mesmo, não possuem conta bancária separada para o seunegócio e consideram contas de água, luz e telefone como custos fixos. Apesar disto, houve associação entre maior faixa etária e fazer a própriagestão financeira e entre possuir conta bancária separada e atenderconvênio. Conclui-se que os profissionais analisados realizam a gestãofinanceira predominantemente por intuição o que sugere uma formaçãoincipiente nesta temática
High-temperature Oxidation behavior of Cu0.3Cr2Fe2Ni3Mn2Nbx high-entropy alloys
Authors: Zhao Rui-feng , Yu Yuan , Jiang Ai-yun , Ren Bo 
Published: February 2025

Abstract
The high-temperature oxidation performance of Cu0.3Cr2Fe2Ni3Mn2Nbx (x=0, 0.2, 0.4 mol, named Nb0, Nb0.2, and Nb0.4, respectively) high-entropy alloys (HEAs) was investigated using a constant-temperature oxidation discontinuous weighing method at 800 °C. The high-temperature oxidation of the three HEAs follows a parabolic law. After 50 h of oxidation, the Nb0.4 alloy has the lowest oxidation weight gain, approximately 0.016 mg·cm-2. As the Nb content increases, the Kp value of HEAs decreases. The Kp value of the Nb0.4 alloy is smallest, about 1.52 × 10-11 g2·cm-4·s-1, indicating that an increase in Nb content can effectively improve the oxidation resistance of Cu0.3Cr2Fe2Ni3Mn2Nbx HEAs. The outer layer primarily contains O and Mn, while the inner layer includes O, Cr, Mn, and/or Nb. The oxidation mechanism is mainly the outward diffusion of metal cations and the inward permeation of O ions. The Nb element improves the high-temperature oxidation resistance of the alloy through the dual effects of thermodynamic stability and kinetic diffusion inhibition.
High-resolution hydrometeorological and snow data for the Dischma catchment in Switzerland
Authors: Magnusson Jan , Bühler Yves , Quéno Louis , Cluzet Bertrand , Mazzotti Giulia , Webster Clare , Mott Rebecca , Jonas Tobias 
Published: February 2025

Abstract. We present an hourly hydrometeorological and snow dataset with 100 m spatial resolution from the alpine Dischma watershed and its surroundings in eastern Switzerland, including station measurements of variables such as snow depth and catchment runoff. This dataset is particularly suited for different modelling experiments using distributed and process-based models, including physics-based snow and hydrological models. Additionally, the data are highly useful for testing various snow data assimilation schemes and for developing models representing snow–forest interactions. The dataset covers 7 water years from 1 October 2016 to 30 September 2023. The complete domain spans an area of 333 km2 with altitudes ranging from 1250 to 3228 m. The Dischma Basin, with its outlet at 1671 m elevation, occupies 42.9 km2. Included in the dataset are high-resolution (100 m) hourly meteorological data (air temperature, relative humidity, wind speed and direction, precipitation, and long- and shortwave radiation) from a numerical weather predication model and rain radar, land cover characteristics (primarily forest properties), and a digital elevation model. Notably, the dataset includes snow depth acquisitions obtained from airborne lidar and photogrammetry surveys, constituting the most extensive spatial snow depth dataset derived using such techniques in the European Alps. Along with these gridded datasets, we provide daily quality-controlled snow depth recordings from seven sites, biweekly snow water equivalent measurements from two locations, and hourly runoff and stream temperature observations for the Dischma watershed. The data compiled in this study will be useful to further develop our ability to forecast snow and hydrological conditions in high-alpine headwater catchments that are particularly sensitive to ongoing climate change. All data are available for download at https://doi.org/10.16904/envidat.568 (Magnusson et al., 2024).
"The Impact of AI on Pharma R&D: Accelerating Innovation in Drug Developments"
Authors: Rakesh Paul  
Published: February 2025

The paper investigates how AI technologies, particularly machine learning, with deep learning and natural language processing, transform drug development processes. The pharmaceutical R&D sector transforms its operations through artificial intelligence technology implementation into industry operations. Pharmaceutical R&D operates more efficiently with AI implementation because they can reach drug market launches quickly with precise drug development results obtained at reduced research costs through shorter product development frameworks. This initial part highlights how conventional research development encounters increasing barriers due to high project fees and numerous unsuccessful outcomes AI intervention becomes essential. The analysis combines literature research, pharmaceutical case studies and expert professional interviews to develop findings. The research employed data derived from peer-reviewed publications and corporate reports as well as AI conference papers. The research studies how AI is implemented through three core R&D segments that concentrate on target discovery together with drug transformation operations alongside clinical trial optimization initiatives. The evaluation of drug development acceleration examines two advanced tools, which consist of AI-powered molecular modeling and predictive analytics. Pharmaceutical research development speeds quickly transform through AI systems, which improve operational effectiveness across drug discovery and development processes. AI technology has proven to reduce pharmaceutical timelines while decreasing production costs while simultaneously improving predictive abilities for decision support. Pharmaceutical R&D organizations speed up development processes with AI technology to address critical global health needs, according to research findings. AI exploitation in the pharmaceutical sector needs a complete evaluation of ethical components with regulatory structures and expert workforce deployment approaches.
Rural tourism the path of empowering rural Development special reference to Santal tribal villages near Santiniketan ,West Bengal
Authors:   Associated with SCMS, Pune, Chatterjee Dr. Dewali 
Published: February 2025

Rural tourism is an integral part of rural culture. Rural tourism creates its strong foundation based on the characteristics of the region where the tourism activities take place. The development of rural tourism can contribute to both socio-economic development and environmental benefits for the people within rural areas. It has significant contribution in society, fostering business growth, income generating potential and ensuring a better livelihood for rural inhabitants. One of the most important strategies to solve the problems and challenges of rural areas is rural tourism development. In recent decades, rural tourism has been considered as an approach for the economic development of sensitive places, especially in remote areas where unbound natural beauty has been observed.

In today’s world significance of rural tourism gaining propriety in order to improve the quality of tourist comfort, protect, manage, secure & promote the great natural and cultural heritage in rural areas. It is tried to use the tourism development strategy to solve rural challenges such as poverty, migration, improving income, diversifying jobs, reducing pressure on nature, improving the quality of life, improving the level of technology, improving environmental and physical conditions ,population stability, improving public services, and socioeconomic stability. The present study attempts to analyse the socio-economic condition of rural people and tribes also and future prospect of rural tourism in Birbhum District, West Bengal, India. This is an effort towards promoting Rural tourism and to preserve the culture and heritage of rural West Bengal. Santiniketan is a unique place of tourist attraction as it was the home of Nobel Laureate Rabindranath Tagore for a major part of his life. It is situated in a predominantly tribal belt in one of the backward districts of West Bengal. Tribals are a primitive and underdeveloped community of the society. This .paper discusses the rural livelihood & tribal villages and their cultural heritage. This paper also highlights the future prospect of rural sustainable tourism based on santals villages Ballavpur Danga. Socio- economic infrastructural developments of tribal (santal) people have been analysed in this work.

Keywords: socio economic development, rural livelihood, tribal villages, rural tourism, Santal tribe
ADICIÓN DE DOS COMPLEJOS ENZIMÁTICOS A RACIONES CON HARINA DE SOYA (Glycine max L.) CON DIFERENTE SOLUBILIDAD DE PROTEÍNA Y RESPUESTA PRODUCTIVA EN POLLOS DE ENGORDE
Authors: Ojeda Alvaro J. , Nuñez Marco T. , Araque Humberto , Rossini Mario B. , Machado Isamery M. , De Basilio Vasco A. 
Published: February 2025

<p>To evaluate the effect of two exogenous enzymatic complex (EEC) in diets with soybean meal with different protein solubility on the performance of broilers, 990 Cobb chickens from 8 to 42 days were assigned in a completely randomly design with factorial arrangement 3x2, to diets with soybean meal with 73, 80 and 86% of KOH solubility, and the on top addition (Soy73E, Soy80E and Soy86E) or not (Soy73, Soy80 and Soy86) of a proteolytic (Allzyme VegPro<sup>®</sup>) and fibrolytic (Allzyme SSF<sup>®</sup>) EEC. The EEC did not affect (P&gt;0.05) live weight variation (58.9 ± 1.2 g/anim/d), feed conversion (1.95 ± 0.04), viscosity (1.35 ± 0.07 cps) neither intestinal pH (6.5 ± 0.1), increasing the intake on Soy 86 in 3.5 and 2.8% for finishing and total cycle. EEC increased the crypts depth (P=0.052) on 7.1%, and intestinal lesions were lower on Soy73. The EEC addition increased the feed intake when soybean meal had the lower thermal processing, and increased the crypts depth in intestinal villi, without variations in live weight, feed conversion, pH neither intestinal viscosity. </p>
Sistem Pendukung Keputusan Pemberian Kredit Bagi Debitur Dengan Metode TOPSIS dan SAW
Authors: Hidayat Muhammad , Lubis Imran , Handoko Divi 
Published: February 2025

Sistem Pendukung Keputusan (SPK) telah menjadi komponen integral dalam lingkungan bisnis modern untuk membantu pengambilan keputusan yang lebih efektif dan efisien. Salah satu aplikasi yang krusial dalam bisnis pembiayaan adalah pengelolaan pembiayaan kenderaan. Dalam konteks ini, penelitian ini bertujuan untuk mengembangkan sebuah Sistem Pendukung Keputusan Pembiayaan Kenderaan dengan memadukan metode Simple Additive Weighting (SAW) dan Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS). Studi kasus dilakukan di PT. ITC Multi Finance, sebuah perusahaan pembiayaan yang berkonsentrasi pada pembiayaan kenderaan. Pendekatan gabungan SAW dan TOPSIS dipilih untuk mengoptimalkan pengambilan keputusan pembiayaan kenderaan, mengingat kompleksitas faktor yang harus dipertimbangkan seperti suku bunga, tenor, nilai kendaraan, dan risiko kredit. Metode SAW digunakan untuk memberikan bobot pada setiap faktor yang relevan dan menghasilkan skor untuk setiap alternatif pembiayaan. Di sisi lain, metode TOPSIS digunakan untuk menghitung jarak relatif dari setiap alternatif terhadap solusi ideal positif dan solusi ideal negatif, menghasilkan urutan preferensi.Hasil uji coba menunjukkan bahwa sepuluh konsumen yang mengajukan pembiayaan kenderaan, terdapat tiga konsumen yang ditolak dikarenakan nilainya dibawah 0,5 dan tujuh konsumen yang layak mendapatkan pembiayaan kenderaan karena mendapatkan nilai lebih besar dari 0,5 dan juga mendapatkan respons positif dari konsumennyaKata Kunci: Pembiayaan, SAW, TOPSIS, SPK.
Sosialisasi Meningkatkan Literasi Keuangan Dan Pengelolaan Zakat di PWBI Kel. Kwala Berkala Kec. Medan Johor
Authors: Harahap Azrai , Haidir Haidir , Harahap M. Guffar , Saragih Alkausar , Sari Indah Mayang , Salsabila Suci Khairina 
Published: February 2025

Pengabdian masyarakat ini bertujuan untuk meningkatkan literasi keuangan dan pengelolaan zakat di Perhimpunan Warga Bhakti Islam (PWBI) Kelurahan Kwala Berkala Kecamatan Medan Johor. Literasi keuangan dan pengelolaan zakat yang baik sangat penting untuk memberdayakan masyarakat dalam pengelolaan finansial dan pertumbuhan ekonomi yang berkelanjutan. Metode pelaksanaan pengabdian masyarakat ini mencakup serangkaian kegiatan seperti workshop, pelatihan, dan penyuluhan kepada anggota PWBI. Kegiatan ini dirancang untuk memberikan pemahaman yang komprehensif tentang konsep dasar literasi keuangan dan strategi pengelolaan zakat yang efektif. Dalam pelaksanaannya, dilakukan pendekatan partisipatif yang melibatkan aktifitas kolaboratif antara pengelola pengabdian, narasumber ahli keuangan, dan anggota PWBI. Evaluasi dilakukan melalui penilaian pre dan post-program, serta pemantauan perubahan perilaku dan pengetahuan anggota PWBI selama pelaksanaan program. Hasil pengabdian menunjukkan peningkatan signifikan dalam literasi keuangan dan pemahaman pengelolaan zakat di kalangan anggota PWBI Kelurahan Kwala Berkala. Peserta program menunjukkan peningkatan dalam kemampuan perencanaan keuangan, pemahaman tentang instrumen keuangan, dan implementasi pengelolaan zakat yang lebih efektif. Dengan meningkatnya literasi keuangan dan pengelolaan zakat, diharapkan anggota PWBI dapat mengoptimalkan pengelolaan sumber daya keuangan mereka, serta meningkatkan kontribusi zakat untuk mendukung program kesejahteraan masyarakat. Hasil pengabdian ini memberikan kontribusi pada upaya pemberdayaan masyarakat dalam konteks literasi keuangan dan pengelolaan zakat, sekaligus dapat dijadikan referensi bagi pengembangan program serupa di komunitas lain. Kata Kunci: Meningkatkan Literasi, Keuangan, Menejemen Zakat