bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study of microbial colonization of catheters for prolonged regional anesthesia when using different fixation methods
Authors: Yakovleva Ekaterina S. , Diordiev Andrey V. , Adkina Elena A. , Shagurin Roman V. , Yakovlev Sergey V. , Kulagina Yuliya M. , Golovinskaya Nadezhda A. 
Published: November 2022

BACKGROUND: Infectious complications related to prolonged epidural and peripheral regional anesthesia are quite rare. However, this does not exclude the necessity of strict adherence to measures aimed at preventing microbial colonization of catheters for regional anesthesia. Microbial colonization of the catheter is not always accompanied by the development of infectious complications but increases the likelihood of their occurrence.
AIM: To determine the frequency of colonization, the qualitative and quantitative composition of the microflora depending on the various methods of fixing of the catheter and the duration of its use.
MATERIALS AND METHODS: 76 patients from 2 to 18 years old with prolonged epidural or peripheral anesthesia were included in an comparative, prospective, randomized, single-center study. Patients were divided into the groups according to the method of catheter fixation - adhesive sticker (AS), adhesive sticker and antimicrobial coating Desitol B (AS+D) and tunneling (T). Determination of microbial contamination of catheters was carried out using classical bacteriological studies.
RESULTS: None of the 76 patients had signs of a local or systemic infection. The difference in the frequency of colonization between the AS and T groups was statistically significant: 2 (1, n = 54) = 5.5381 (p = 0.018), between the AS and AS+D groups it was not significant. The relative risk of colonization of the skin of the catheter with adhesive fixation was 2.14 times higher than with catheter tunneling: RR = 2.14, p = 0.05 (95% CI 1.04.49). In the AS+D group, colonization of both the skin and the inner part of the catheter was observed significantly earlier than in the T group: skin part: U = 5.5; Ucr = 8 (p = 0.02); inner part: U = 5.5; Ucr = 6 (p = 0.04). The growth of Staphylococcus epidermidis (48.3%) and Staphylococcus aureus (20.7%) was fixed mainly when positive results of microbiological culture takes place.
CONCLUSIONS: Tunneling is the preferred method of fixation of the catheter when the postoperative pain relief period is more than 3 days.
Clinical and functional features of chronic pyelonephritis in children with connective tissue dysplasia
Authors: Ivanova Irina I. , Koval Natalia Yu. 
Published: November 2022

BACKGROUND: There is information in the literature about the effect of connective tissue dysplasia (СTD) on the course of many somatic diseases. The role of СTD in the development of chronic pyelonephritis (СhPN) is presented differently to different authors, which is why it became necessary to conduct this study.
AIM: The aim of the work is to evaluate the effect of СTD on the course and manifestations of chronic secondary pyelonephritis in children.
MATERIALS AND METHODS: 142 children from 6 to 17 years old with СhPN were examined. They were divided into 2 groups: the 1st group included 108 children with manifestations of СTD, including 41 people with СTD of the 3rd degree and 67 people with СTD of the 2nd degree; group 2 34 patients without СTD. The groups were comparable in gender and age. The examination was carried out according to the standards for patients with ChPN. Signs of СTD were evaluated by the method of T.I. Kadurina.
RESULTS: Obstructive and mixed variants of СhPN are typical for children with СTD. In most patients, the disease manifested at 12 years of life; at school age the first signs of the disease occurred mainly in children without СTD with dysmetabolic disorders. Relapses of СhPN in children with СTD occurred 1.5 times more often during the year and 2,1 times more often during 5 years of follow-up. Patients with СTD are characterized by a wider range of pathogens, anemia, a high incidence of structural abnormalities and urodynamic disorders, a tendency to form foci of nephrosclerosis. The need for surgical treatment in the presence of СTD increases in patients with СhPN by 4.6 times, including in repeated and radical operations. In children with grade 3 СTD, all these signs are more represented.
CONCLUSIONS: СTD affects the course and manifestations of СhPN in children, creating an unfavorable background. It seems promising to study the role of СTD in the occurrence of anemia in children with СhPN.
Urinary biomarkers in children with kidney diseases taking into account obesity
Authors: Nastausheva Tatiana L. , Chan Anna V. , Kulakova Elena N. , Volosovets Galina G. , Chichuga Ekaterina M. , Chubarov Timofey V. , Gurovich Olga V. , Grebennikova Irina V. 
Published: November 2022

BACKGROUND: Overweight and obesity in children are one of the most serious problems of the modern world. There are mane publications devoted to kidney injury in patients with obesity. This injury in developed imperceptibly, without clinical symptoms. Probably the diagnostics of kidney injury in children with obesity may be improved by studying new urinary markers: KIM-1, NGAL, IL-18, 2-mg.
AIM: Aim of our study was the comparative analysis of urinary markers of tubular kidney injury (KIM-1, NGAL, IL-18, 2-mg) in children with obesity and kidney diseases.
MATERIALS AND METHODS: We have been studied 78 children aged 715 years: 40 children with different kidney diseases and 38 patients with obesity and kidney diseases. The results of the study were presented as markers concentration in urine and as relation to creatinine (normalized indicators).
RESULTS: In children with obesity and kidney diseases the level of KIM-1 was more high in comparison with the children without obesity. The concentration of other markers (NGAL, IL-18, 2-mg) did not differ in children of two groups. The same results were received when analyzing normalized indicators. It was appeared significant correlation between body mass of patients and NGAL of urine in both groups.
CONCLUSIONS: Investigation of urinary KIM-1 have significance for diagnostics of tubular kidney injury in children with obesity on the background of kidney diseases. Established significant correlation NGAL with body mass can testify about it is diagnostic significance for obesity regardless of kidney diseases.
Chronic obstructive lung diseases as a risk factor for severe COVID-19 (review)
Authors: Kulikov Valery D. , Sukhovskaya Olga A. , Smirnova Maria A. , Kuzubova Nataly A. , Titova Olga N. 
Published: November 2022

The review presents meta-analyses and original studies data of severe outcomes of COVID-19 infection in patients with chronic obstructive pulmonary disease.
The main risk factors for the severe course of COVID-19 in many studies have been identified as follows: age over 65 years, chronic lung diseases, systemic arterial hypertension, cardiovascular diseases, diabetes mellitus, immunosuppression, chronic kidney and liver diseases. It was shown that patients with concomitant respiratory diseases were 4.2 times more likely to have a severe course of COVID-19 (OR 4.21; 95% CI 2.96.0), especially in patients with chronic obstructive pulmonary disease (OR 5.8, 95% CI 3.98.5). Patients with bronchial asthma also more often received mechanical ventilation (OR 1.58; 95% CI 1.022.44; p = 0.04), treatment in intensive care units (OR 1.58; 95% CI 1.092.29; p = 0.02), had longer hospital stays (OR 1.30; 95% CI 1.091.55; р 0.003) and higher mortality (OR 1.53; 95 % CI 1.012.33; p = 0.04) compared with COVID-19 patients without asthma or other chronic obstructive pulmonary diseases. Another factor contributing to severe outcomes of COVID-19 is tobacco use, which increases the risk of severe disease, hospitalization and poor outcomes.
Patients with chronic obstructive pulmonary diseases, especially smokers, were more likely to have a severe COVID-19 and adverse outcomes of this disease, which must be taken into account when prescribing treatment for coronavirus infection.
Evaluation de L’impact de L’entrepreneuriat sur la Croissance Economique au Cameroun: une Analyse Econométrique
Authors: Gildas Boris Dudjo Yen , Eboue Roméal , Ewondo Mbebi Oliver 
Published: December 2022

L’entrepreneuriat est au cœur des politiques de développement. Les gouvernements se trouvent toutefois confrontés à un défi nouveau, car favoriser l’entreprenariat en tant qu’institution socioéconomique est une démarche qui diffère très sensiblement de celle à adopter pour concevoir et mettre en œuvre d’autres mesures de politique économique. Pour dynamiser la création d’entreprise, le gouvernement Camerounais a élaboré des programmes et politiques afin d‘encourager davantage l’activité entrepreneuriale pour une économie qui se veut émergente. En vue d’évaluer l’impact de l’entrepreneuriat sur la croissance économique au Cameroun sur la période de 2005 à 2020, nous avons appliqué la méthode d’estimation ARDL (Autoregressive Distributed Lag). Les résultats montrent qu’à court terme, l’impact de l’entrepreneuriat sur la croissance est positif et significatif. À long terme, nous constatons un résultat similaire car l’entrepreneuriat exerce un effet positif et significatif. Ces résultats sous-entendent que les pouvoirs publics doivent davantage mettre un accent sur la création des start-ups.

Entrepreneurship is at the heart of developing policies. Governments are at all times faced with challenges because promoting entrepreneurship as a socio-economic institution is a significant approach different from that to be adopted to design and implement other measures of economic policies. To boost business creation, the Cameroonian government has developed programs and policies to further encourage entrepreneurial activity in an emerging economy. To encourage entrepreneurial activity in an emerging economy. To evaluate the entrepreneurship impact on economic growth in Cameroon over the period of 2005 to 2020, we applied the ARDL (Autoregressive Distributed Lag) estimation method. The results show that in the short term, the entrepreneurship impact on growth is positive and significant. In the long term, we find a similar result because entrepreneurship exercises a positive and significant effect. These results imply that public authorities should put more emphasis on the creation of start-ups.
Procedural knowledge or conceptual knowledge? Developing the so-called proceptual knowledge in mathematics learning
Authors: Barumbun Mardyanto , Kharisma Dian 
Published: November 2022

[English]: Some students might have the proper knowledge to use mathematical procedures where relevant, but do they actually have a solid understanding of “why or how” those procedures work? Such an incomplete understanding of mathematics concepts can be a stumbling block in students’ success in mathematics. This paper aims to propose and elaborate a framework for developing proceptual knowledge combining both procedural and conceptual knowledge on differentiation that are constructed on existing mathematics learning theories on how we understand mathematics, besides my personal reflections from the independent learning on differentiation. The theoretical and practical perspectives proposed in this article share insight with anyone in developing a more meaningful mathematics-independent learning experience, especially on topics with complex mathematical formulas or procedures, such as differentiation.
[Bahasa]: Sebagian siswa mungkin memiliki pengetahuan yang tepat dalam menggunakan prosedur matematika secara relevan, namun apakah mereka sungguh memiliki pemahaman yang utuh tentang "mengapa atau bagaimana" prosedur matematika tersebut diperoleh? Pemahaman yang tidak utuh tersebut berpotensi menjadi penghalang kesuksesan siswa dalam memahami konsep matematika. Artikel ini mengusulkan kerangka kerja untuk mengembangkan proceptual knowledge (pengetahuan proseptual) pada materi turunan, yakni kombinasi pengembangan pengetahuan prosedural dan konseptual matematika yang dibangun di atas teori-teori pembelajaran matematika yang ada, serta hasil refleksi pribadi penulis dari proses belajar mandiri tentang konsep rumus diferensial. Perspektif teoritis dan praktis yang diusulkan dalam artikel ini dapat menjadi panduan bagi siapa saja untuk mengembangkan pengalaman belajar matematika yang lebih bermakna, khususnya pada topik dengan rumus dan prosedur matematis yang kompleks seperti pada turunan.
Extent of mobile phone application in farming: A Probabilistic Model
Authors: Oinam Termaric 
Published: December 2022

Abstract
Background
Mobile phones are extremely popular amongst young people, cutting across gender or locality, and can serve for improving efficiency of agricultural markets, promoting investment, and contributing to empowerment. As usage and application of ICT (Information and Communication Technologies) gadgets and gizmos are generally adhered to the youths compared to the old and aged personnel, a thorough understanding on the extent of mobile phones application in farming by tribal rural youth is a right paramount in such a challenging hill agricultural production and knowledge systems of Meghalaya.
Methods
A four stage sampling has been followed in the study. Snowball sampling was implemented to select respondents which brought total respondents to 240. All of the respondents were tribal rural youth farmers between 19–35 years. One of the indifferent criterions for the sample rural youth will be the farmer who possesses a smart mobile phone. Multinomial logistic regression (MLR) was used to predict the probabilities of the different possible outcomes of a categorically distributed dependent variable, given a set of independent variables.
Results
Parameter estimates showed that annual income, perceived ease of use, mobile phone service reliability, money spent on mobile phone monthly have no impact on the use of mobile phone application in farming whilst agricultural land holding, decision making, perceived usefulness and education have significant bearings on the extent of mobile phone application in farming.
Impaired Hip Strategy in Multiple System Atrophy (MSA) and Spinocerebellar Ataxia (SCA)
Authors: Wang Yuzhou , Liu Churong , Ma Gengmao , Lv Xiao , Ye Jinlong , Xu Yan , Li Zhong , Li Xiaodi 
Published: December 2022

AbstractBackground: Postural sway could be separated into several components according to frequencies. Higher frequency sway is indicative of hip strategy but how is it impaired in ataxia patients is still unknown.Methods: Static posturography examination were administered to 37 patients with spinocerebellar ataxia (SCA), 58 patients with the cerebellar type of multiple system atrophy and 53 healthy controls. Energy value trajectory during the four-step sensory organization tests were evaluated by generalized additive mixed model (GAMM). Repeated measures correlation analysis between energy value/proportions and postural performance (total postural sway, fall and tremor occurrence) were also performed.Results: GAMM analysis revealed that the middle frequency band proportion did not increase with test difficulties in MSA and SCA, indicating a failure of frequency shift. Repeated measures correlation analysis revealed that the highest correlation coefficient between energy values were found between MFV and HFV in healthy controls, illustrating components of a complete hip strategy, which was not found in SCA or MSA. In normal adults, there is a significant and positive relationship between MFP and HFP with total energy values, illustrating frequency shifts of normal stance. However, MFP was negatively related with total energy values in SCA (p>0.05) and MSA (p<0.05) patients.Conclusion: Hip strategy was not complete in SCA while it was completely disrupted in MSA, which explains why there were more falls in MSA patients. High frequency band postural sway (>2Hz) is an important component of a complete hip strategy and its origin needs further investigation.
Segments arrangement effect on improvement of self-centering PPS piers seismic performance
Authors: Anzabi P. Poorahad , Shiravand M. R. 
Published: November 2022

AbstractIn bridge engineering, the use of precast post-tensioned segmental (PPS) piers is increasingly expanding due to the Accelerated Bridge Construction viewpoint. Recent experimental and numerical researches have studied general seismic performance and nonlinear behavior of PPS piers without much attention to segment arrangements or joint openings. The aim of this paper is to utilize innovative segment arrangements to reduce the residual deformation, and also enhance the energy dissipation capacity of PPS piers with internal energy dissipation (ED) bars. For this purpose, nonlinear rocking dynamics of a multiple-block assembly of tied rigid rocking blocks equipped with ED bars at joints are firstly developed so that uplift moment for each joint is derived to obtain the threshold joint opening height (height above which no joint opens). Then, nonlinear static, quasi-static, and dynamic analyses are conducted on different segment arrangements of finite element models of PPS piers. It is proposed to place more segments within the threshold joint opening height by using unequal segments so that the total rotation is shared among critical joints (joints that open), and the nonlinear extent of ED bars at the bottom joint is reduced, resulting in the reduced residual deformation. It is also proposed to place a lower ratio of ED bars at the critical intermediate joints or place ED bars of a lower yield stress there so that the intermediate joints can be more effective even with small rotations. Results indicate that using the proposed segment arrangement, enhances both seismic and post-seismic performance of PPS piers.
Efficient Feature Extraction Based on Optimized Gated Recurrent Unit Recurrent Neural Network for Automatic Thyroid Prediction
Authors: Saka Nagavali , Krishna S. Murali 
Published: December 2022

AbstractIn this paper, develop Efficient Feature Extraction Based Recurrent Neural Network (EFERNN). Initially, the databases are gathered from the open-source system. After that, the pre-processing technique is developed for correcting missing values by the normalization technique of min-max normalization. The pre-processed data is utilized for feature extraction by using feature extraction techniques such as Two-Level Feature Extraction (TLFE) techniques. In level1, the ranked filter feature set technique is utilized to rank the features based on doctor recommendations. In order to execute the label-driven validation, ranking measures are used. In level 2, features are ranked and selected using a variety of metrics, including info gain, gain ratio, chi-square, and relief. In level 2, the effective features are chosen from the feature set using a fuzzy-based composite measure. In order to categorise thyroid disease from the databases, the Optimized Gated Recurrent Unit - Recurrent Neural Network (GRU-RNN) is used. In the GRU-RNN, the weight is selected with the assistance of the COOT Optimization Algorithm. The suggested method is put into practise in MATLAB, and its effectiveness is assessed by taking into account statistical measurements like kappa, accuracy, precision, recall, sensitivity, specificity and F Measure. To validate the proposed technique, it is compared with conventional techniques such as Deep Belief Neural Network (DBN). Artificial Neural Network (ANN) and Support Vector Machine (SVM).
New experimental model of chronic renal failure
Authors: Shadmanov A.K. , Okhunov A.O. , Abdurakhmanov F. M. 
Published: December 2022

Abstract
Background.

As is known, the modeling of chronic renal failure against the background of diabetic nephropathy is associated with the need to maximally approximate the conditions for its reproduction to the clinical one. Based on the foregoing, the priority in the reproduction of chronic renal failure should come from the modeling of diabetes mellitus, in particular diabetic nephropathy.

Purpose

To develop an experimental model of chronic renal failure against the background of diabetic nephropathy.

Methods.

Experimental studies were carried out on rabbits with the choice of the optimal method from 5 series of experiments. The evaluation was carried out according to the abortive course of the process, the development of hyperglycemic coma, the presence of angiodillation and the reproducibility of the model. For morphological studies, tissue samples in the form of pieces of kidney tissue were taken by performing an operation under ether anesthesia.

Results.

The 3 stages of nephropathy identified by us during the experiment (I - minor, II - moderate and III - severe) testified to the choice of terms for modeling chronic renal failure. The main criteria for a possible period of transition from nephropathy to the development of chronic renal failure is the presence of hyalinosis of microvessels with thickening of the membranes, which indicated the occurrence of irreversible angiogenic changes. This period is defined by us as 40 days of modeling diabetic nephropathy.

Conclusion.

In the development of chronic renal failure in a model with diabetic nephropathy, both the lack of expression of the angiogenic factor VEGF by podocytes and tubular epithelial cells and the increased expression of the antiangiogenic factor thrombospondin-1 in the renal glomeruli and interstitium play a certain role in the disruption of angiogenesis. Thrombospondin-1 inhibits the proliferation of endothelial cells stimulated by VEGF and oFRF, causing their apoptosis. As a result, the density of glomerular and peritubular capillaries decreases, glomerulosclerosis and interstitial fibrosis develop.
A Survey on Computational Intelligence Applications in Information Retrieval
Authors: Ibrahim Osman Ali Sadek 
Published: December 2022

Abstract
Computational Intelligence (CI) techniques have been widely employed in information retrieval (IR). CI approaches include everything from evolutionary computation and metaheuristics to machine learning techniques. These methods may be classified based on the problem domain for which they are employed in conjunction with the IR dataset representation formats. When utilizing these methods, the Vector Term Model (VTM) and Vector Feature Model (VFM) are the data representation methods that were used. The VTM represents the document and the query as vectors of term-weights. CI approaches are commonly used in VTM in conjunction with the classical Vector Space Model (VSM), while Term-weights are substituted by feature-weights in the VFM to yield feature vectors of query-document pairs. These features represent the query-document similarity matching values (such as cosine similarity and BM25), the query-document term-weights (such as TF-IDF, Okapi, and Language Models), and the document's online reputation. This paper reviews some of the research works on applying CI approaches to the VTM and VFM.