bluuebunny/crossref_metadata_2025_split huggingface dataset:
Involvement of high school teachers in Health Promoting School program in selected township, Yangon Region, Myanmar: A cross-sectional mixed methods study
Authors: Naing Kaung Myat , Htun Ye Minn , Tun Kyaw Myo , Win Tun Tun , Lin Htein , Sein Than Tun 
Published: June 2022

Background
Schools provide a big opportunity for promoting the student’s health, life skill, and behavior. Teachers play a fundamental role in the promotion and successful implementation of school health services. This study aimed to assess the level of involvement in the Health Promoting School program and its associated factors and to explore the benefits and barriers to involvement among high school teachers in Myanmar.

Methods
A mixed methods explanatory sequential study was conducted among 194 high school teachers in Thanlyin Township, Yangon Region, Myanmar, from June to August 2020. Quantitative data were collected with the pretested structural questionnaire and analyzed by Chi-square tests and Fisher’s exact tests. A qualitative strand was added by conducting in-depth interviews (n = 15, five teachers from each level of involvement: poor, medium, and good), analyzed by thematic content analysis.

Results
Of the 194 teachers, 23.7% had a good level of involvement in the Health Promoting School program. The factor associated with involvement in Health Promoting School program were age (p value < 0.001), duration of services (p value = 0.001), and a number of accomplished training-related school health (p value = 0.008). Qualitative data revealed that improvement of the health knowledge and awareness on health problems, the progress of healthy behaviors, development of physical and mental health, prevention of the disease spread, achievement of healthy and productive learning environment, and development of academic achievement were major benefits of teachers’ involvement. Moreover, the main barriers to involvement were insufficient materials and human resources, time constraints, incompetence of the teachers, poor cooperation of school health partnerships, and insufficient awareness of parents.

Conclusions
The proportion of good involvement in the Health Promoting School program among high school teachers was low in this study area. Providing sufficient human resources and material, conducting the on-the-job and refresher training, enhancing parent-teacher cooperation, and strengthening the community partnerships were crucial to improve the level of involvement and reduced the barriers for the achievement of the Health Promoting School program.
Clinical characteristics and risk factors for COVID-19 infection and disease severity: A nationwide observational study in Estonia
Authors: Meister Tatjana , Pisarev Heti , Kolde Raivo , Kalda Ruth , Suija Kadri , Milani Lili , Karo-Astover Liis , Piirsoo Marko , Uusküla Anneli 
Published: June 2022

Background
COVID-19 pandemic has led to overloading of health systems all over the world. For reliable risk stratification, knowledge on factors predisposing to SARS-CoV-2 infection and to severe COVID-19 disease course is needed for decision-making at the individual, provider, and government levels. Data to identify these factors should be easily obtainable.

Methods and findings
Retrospective cohort study of nationwide e-health databases in Estonia. We used longitudinal health records from 66,295 people tested positive for SARS-CoV-2 RNA from 26 February 2020 to 28 February 2021 and 254,958 randomly selected controls from the reference population with no known history of SARS-CoV-2 infection or clinical COVID-19 diagnosis (case to control ratio 1:4) to predict risk factors of infection and severe course of COVID-19. We analysed sociodemographic and health characteristics of study participants. The SARS-CoV-2 infection risk was slightly higher among women, and was higher among those with comorbid conditions or obesity. Dementia (RRR 3.77, 95%CI 3.30⎼4.31), renal disease (RRR 1.88, 95%CI 1.56⎼2.26), and cerebrovascular disease (RRR 1.81, 95%CI 1.64⎼2.00) increased the risk of infection. Of all SARS-CoV-2 infected people, 92% had a non-severe disease course, 4.8% severe disease (requiring hospitalisation), 1.7% critical disease (needing intensive care), and 1.5% died. Male sex, increasing age and comorbid burden contributed significantly to more severe COVID-19, and the strength of association for male sex increased with the increasing severity of COVID-19 outcome. The strongest contributors to critical illness (expressed as RRR with 95% CI) were renal disease (7.71, 4.71⎼12.62), the history of previous myocardial infarction (3.54, 2.49⎼5.02) and obesity (3.56, 2.82⎼4.49). The strongest contributors to a lethal outcome were renal disease (6.48, 3.74⎼11.23), cancer (3.81, 3.06⎼4.75), liver disease (3.51, 1.36⎼9.02) and cerebrovascular disease (3.00, 2.31⎼3.89).

Conclusions
We found divergent effect of age and gender on infection risk and severity of COVID-19. Age and gender did not contribute substantially to infection risk, but did so for the risk of severe disease Co-morbid health conditions, especially those affecting renin-angiotensin system, had an impact on both the risk of infection and severe disease course. Age and male sex had the most significant impact on the risk of severe COVID-19. Taking into account the role of ACE2 receptors in the pathogenesis of SARS-CoV-2 infection, as well as its modulating action on the renin-angiotensin system in cardiovascular and renal diseases, further research is needed to investigate the influence of hormonal status on ACE2 expression in different tissues, which may be the basis for the development of COVID-19 therapies.
Risk of cervical cancer in inflammatory bowel disease: A meta-analysis of population-based studies
Authors: Mann Simran , Jess Tine , Allin Kristine , Elmahdi Rahma 
Published: June 2022

INTRODUCTION:
There is increased risk of several malignancies in inflammatory bowel disease (IBD). However, evidence regarding risk of cervical cancer in IBD is conflicting. We aimed to investigate the risk for cervical cancer in IBD by undertaking a systematic review and meta-analysis of unselected, population-based studies.

METHODS:
Medline, Embase and Cochrane library were searched using Medical Subject Heading (MeSH) terms and 2 reviewers independently screened results. Pooled hazard ratios (HR) were calculated using random effects model (REM) meta-analysis for risk of cervical cancer in IBD. Subgroup meta-analysis was undertaken to assess risk of cervical cancer by IBD subtype (Crohn’s disease [CD] and ulcerative colitis [UC]), treatment exposure and grade of lesion.

RESULTS:
We screened 1,393 articles to identify 5 population-based studies, including 74,310 IBD patients and 2,029,087 reference patients across 5 different countries. Pooled REM meta-analysis of these studies did not show statistically significant increased risk for cervical cancer in IBD compared with reference populations (HR: 1.24; 95% confidence interval [CI]: 0.94-1.63). Meta-analysis by grade of lesion showed increased risk of low-grade cervical lesions (HR: 1.15; 95% CI: 1.04-1.28). Meta-analysis by disease subtype indicated no statistically significant increased risk in CD (HR: 1.36; 95%CI: 0.83-2.23) or UC (HR: 0.95; 95%CI: 0.72-1.25), or in patients treated with anti-tumor necrosis factor (TNF) (HR: 1.19; 95% CI: 0.64-2.21) or thiopurines (HR: 0.96; 95% CI: 0.60-1.50).
CONCLUSIONS: This meta-analysis of high-quality, unselected population-based studies shows no statistically significant increased risk of cervical cancer in IBD patients. There is, however, increased risk of low-grade cervical lesions compared with the general population.
Sulfadiazine crystalluria in a patient with lupus nephritis
Authors: Ruiz Álvarez Maria Jesús , Molina Blas Sergio , Barrionuevo González Marta , Peñas Lorite M. Eugenia , Gasalla Herraiz José Manuel 
Published: June 2022

Abstract

Objectives
It is estimated that 29% of patients treated with sulfadiazine ultimately develop acute kidney failure. Diagnosis is based on urine sediment analysis.

Case presentation
A 71-year-old woman with loss of visual acuity in the context of a flare of systemic erythematosus lupus (SEL). A diagnosis of acute retinal necrosis was established, pending etiological confirmation. Empirical treatment with sulfadiazine was initiated. Follow-up analyses included urine sediment, which revealed pH 6, 30–50 RBCs/field, urothelial cells and lower tract epithelial cells, hyaline casts, fatty casts or Maltese cross, and abundant sulfadiazine crystals. The finding was reported to the Unit of Nephrology, and treatment was immediately suspended.

Conclusions
Sulfadiazine is an antibiotic of the family of sulfamides. Crystalization of sulfadiazine in the renal tubules may cause acute interstitial nephritis. These crystals adopt different shapes according to the metabolite that crystalizes: unaltered forms precipitate into dense, globular crystals, whereas in other cases, as in the case reported in this paper, crystals adopt a fan-shaped, shocks-of-wheat morphology.
Potential tumor marker for hepatocellular carcinoma identification: PI3K and pro-inflammatory cytokines (TGF-β, IL-1, and IL-6)
Authors: Tabakhiyan Fahimeh , Mir Amirabbas , Vahedian Vahid 
Published: June 2022

Abstract

Objectives
Hepatocellular carcinoma (HCC), the most common form of liver cancer, is a leading cause of tumor-associated mortality worldwide. Diagnosis based upon non-invasive criteria is currently challenged by the need for molecular information that requires tissue or liquid biopsies. The progression of HCC is often associated with chronic inflammation, expression levels of inflammatory mediators, chemokine, and cytokines. In this study, we try to evaluate the PI3K and pro-inflammatory cytokines, TGF-β, IL-1, and IL-6 expression level in patients with liver cancer.

Materials and methods
The kupffer cells were isolated from patient’s specimens. Real-time PCR was applied to evaluate the expression level of PI3K in cell lines or tumors. The concentrations of TGF-β, IL-1, and IL-6 were measured by the quantitative ELISA kit.

Results
PI3K mRNA expression in cancer cells was increased markedly vs. normal cells. The ELISA results demonstrated over expression of TGF-β, IL-1, and IL-6 in patients and positive correlation between tumor size and stage.

Discussion
This study suggests that targeting the expression level of PI3K and pro-inflammatory chemokine and cytokines, TGF-β, IL-1, and IL-6, may be a potential diagnostic strategy in HCC patients.
Combined impact of Marangoni convection and thermophoretic particle deposition on chemically reactive transport of nanofluid flow over a stretching surface
Authors: Madhukesh Javali Kotresh , Mansir Ibrahim B. , Prasannakumara Ballajja Chandrappa , Khan Muhammad Ijaz , Alharbi Khalid Abdulkhaliq M. , Abdelrahman Anas , Khan Muhammad , Ramesh Gosikere Kenchappa , El-Sayed Ahmed Ahmed 
Published: June 2022

Abstract
The impact of Marangoni convection has noteworthy applications in nanotechnology, atomic reactor, silicon wafers, semiconductor processing, soap films, materials sciences, thin-film stretching, crystal growth, and melting and welding processes. On the other hand, thermophoretic particle deposition (TPD) has a significant application in building ventilation systems, crushed coal burners, thermal exchangers, and air cleaners. Inspired by these applications, the present work mainly concentrates on the Marangoni convection flow of Al2O3/water-based nanofluid over a stretching sheet in a porous medium with TPD in the presence of Newtonian heating. Additionally, heat absorption/generation in energy expression is considered. A suitable similarity variable is applied to simplify the partial differential equations into a set of ordinary differential equations (ODEs). Furthermore, Runge Kutta Fehlberg fourth fifth order method along with the shooting technique is implemented to solve the reduced ODEs. Furthermore, mathematical computational software helps to acquire a numerical solution. The velocity of nanofluid increases for enhancement of Marangoni number and diminishes for porosity parameter. The heat absorption/generation parameter improves thermal dispersion in both common wall temperature and Newtonian heating cases. For the upgradation in the thermophoretic parameter, the concentration decreases and the rate of mass transfer increases. The rate of heat transfer increases as the heat source parameter grows and decreases as the heat sink parameter decreases. In all of the profiles, nanofluid outperforms viscous fluid.
Characterization and tribology performance of polyaniline-coated nanodiamond lubricant additives
Authors: Huang Ruoxuan , Han Shinan , Zhang Tianchi , Wang Zichun , Kostyantyn Grinkevych , Chen Xiangnan , Xu Jiujun 
Published: June 2022

Abstract
The polyaniline (PANi)-coated nanodiamond (ND) composites were fabricated by the in situ polymerization process and dispersed in base oil as nanolubricant additives by ultrasonic-assisted dispersion. The morphology and microstructures of the nanocomposites were characterized. The in-house developed reciprocating tribo-device was utilized to conduct the tribological tests. An actual CrN piston ring–nitriding cylinder liner friction pair used in the diesel engine was employed to evaluate the effectiveness of the developed nanolubricant additives. The wear tests were conducted under conditions that were close to the actual work condition of the selected friction pair. Furthermore, the anti-scuffing performance was also investigated and the associated mechanisms were analyzed. The results show the polymerization process inhibited the agglomeration of the NDs that were well dispersed in the PANi matrix. The stable hydrogen bonding interactions and the surface confinement effect promote the dispersion of the nanocomposites in organic base oil effectively. The developed additive can improve the friction and wear performance of the ring–cylinder liner friction pair by 12–19 and 15–24%, respectively, compared with the base oil. With the increase of temperature, the effectiveness of the nanolubricant additives is enhanced. Under the oil-starved condition, the friction pairs lubricated with PANi/ND lubricants can sustain a longer stable period with a lower friction force, and the anti-scuffing time is almost three times longer. Concerning the overall tribological performance, the optimal content of the PANi/ND additive in base oil is 2 wt%.
Phenotyping cowpea accessions at the seedling stage for drought tolerance in controlled environments
Authors: Nkomo Gabriel V. , Sedibe Moosa M. , Mofokeng Maletsema A. 
Published: June 2022

Abstract
One of the most important screening techniques used in cowpea selection for drought tolerance is screening at the seedling stage. The objective of this study was to phenotype 60 cowpea genotypes for seedling drought tolerance in screen houses (glasshouse and greenhouse). Principal component analysis revealed that of the 14 variables, the first 4 expressed more than 1 eigenvalue. Data showed that PC1, PC2, and PC3 contributed 39.3, 15.2, and 10%, respectively, with 64.68% total variation. A PCA plot and biplot showed that the number of pods (NP), seeds per pod (SP), survival count (SC), pod weight (PWT), and stem wilting in week 1 (WWK1) had the most significant contributions to genetic variability to drought tolerance and to yield after stress imposition based on the PCA, biplot, and cluster plot, the accessions IT 07-292-10, IT 07-274-2-9, IT90K-59, 835-911, RV 343, and IT 95K-2017-15 had the maximum variability in terms of NP, SP, SC, PWT, and WWK1 after drought imposition. Cowpea accessions 835-911, IT 07-292-10, RV 344, Kangorongondo, and IT 90K-59 were the major individuals that contributed mainly to domain information model (DIM) 1 and 2. The accessions that contributed the least were IT 89KD288, Chibundi mavara, and TVU12746. Thirty-six cowpea accessions from both screen houses were tolerant to drought, 15 were moderately tolerant, while 23 were susceptible. The findings of the study provided a useful tool for screening and determining drought-tolerant and susceptible accessions at the seedling stage.
10 Jahre Leerverkaufsverordnung
Authors: Krafft Daniel 
Published: June 2022

Zusammenfassung
Mit der Leerverkaufsverordnung hat der europäische Gesetzgeber im Jahre 2012 auf die unterschiedlichen nationalen Maßnahmen im Zuge der Finanzkrise 2008 reagiert. Passend zum zehnjährigen Jubiläum im Jahr 2022 veröffentlichte die ESMA einen „Final Report“ zur Leerverkaufsverordnung. Der Beitrag nimmt dies zum Anlass, die bisherige Bedeutung der Leerverkaufsverordnung für die Praxis darzulegen und die Regelungssystematik sowie die aktuellen Entwicklungen zu evaluieren.
Private Enforcement des Marktmanipulationsverbots – Haftung bei Verstößen gegen Art. 15 MAR?
Authors: Scholz Marcel 
Published: June 2022

Zusammenfassung
Die Neuregelung des Marktmanipulationsverbots in Art. 15, 12 MAR hat seit einigen Jahren (erneut) die Diskussion entstehen lassen, ob eine zivilrechtliche Haftung desjenigen, der gegen das Manipulationsverbot verstößt, angezeigt ist. Im deutschen Recht könnte sich eine solche Haftung primär bei einer Qualifikation von Art. 15 MAR als Schutzgesetz i. S. d. § 823 Abs. 2 BGB ergeben. Neben den Erwägungen rund um einen Individualschutz des Marktmanipulationsverbots sind jedoch zugleich auch die unionsrechtlichen Grundlagen in die Betrachtung mit einzubeziehen. Insofern stellt sich insbesondere die Frage, ob und wie sich diese in das Gesamtsystem des deutschen Deliktsrechts einfügen. Neben allgemeinen deliktsrechtlichen FragestellunFragestellungen gen sind somit zugleich das Zusammenspiel von Unionsrecht und nationalem Recht sowie die Auswirkungen des Unionsrechts auf das deutsche Deliktsrecht angesprochen.
The Hungarian question tag mi? As characterized by dependent and independent commitments
Authors: Kiss Angelika 
Published: June 2022

Abstract
The Hungarian question tag mi? is subject to more special contextual restrictions compared to ugye?. An utterance that features mi? i) tentatively commits the addressee as a source for the anchor proposition of the tag question, and ii) it commits the speaker as a source for the addressee's being a source for p, which is a pragmatic presupposition. A speaker is a source for a proposition p if that speaker's commitment to p does not depend on any other discourse participant's commitment (Gunlogson 2008). The results of an online survey of a minimal set of pragmatically relevant contexts support claim i), and indirectly, claim ii). The effect of mi? on the immediate context of the discourse is modeled on a conversational scoreboard (Farkas & Bruce 2010; Malamud & Stephenson 2015).
Pushed out of arm's reach: Pronouns and spatial anaphora in Hungarian
Authors: Rákosi György , Tóth Enikő 
Published: June 2022

Abstract
This paper investigates hitherto unnoticed variation in the linguistic coding of spatial anaphora in locative PPs in Hungarian. While Hungarian primarily employs reflexives in these configurations, it is well-known that pronouns are the default strategy in English, and the reflexive anaphor is allowed in locative PPs only in the presence of certain licensing factors. One such factor is the availability of body-oriented readings (Rooryck & Vanden Wyngaerd 2007, 2011), and we argue here that this plays an important role in Hungarian, too. The paper reports the findings of a corpus study and an online questionnaire study and shows that pronouns are not only acceptable in Hungarian spatial anaphora, but either outperform or form a viable alternative to reflexives when the location denoted by the PP is not close to the referent of the antecedent. A secondary effect of structure building is also observable in two configurations of the extended PP. We argue that the employment of a possessive structure in certain PPs, and moving a P-element to a CPPP cap may also contribute to saving pronouns in contexts of spatial anaphora.
Pedagogisk forskning är bra!
Authors: Hultman Glenn 
Published: June 2022

I detta inlägg fokuserar jag på forskningens olika funktioner i olika sammanhang men även det praktiknära och användningen av forskning. Vad är det som legitimerar forskning och hur fungerar den i olika miljöer? När det gäller användning av forskning behöver vi påminna oss om att det finns andra sidor av ”användning” som innebär att olika aktörer kan använda forskning på ett helt annat sätt än forskaren hade tänkt sig.
Pedagogisk forskning ger möjligheter att ta del av analyser och resultat, är bra som ett komplement till den praktiknära analysen, bidrager till insikter kring val av metoder, analyser och formandet av teorier. Den bidrager till en nyorientering och/eller en problematisering av ett forskningsområde och kan bidra till lärande och insikter.
Manajemen Layanan Khusus Peserta Didik Bidang Bimbingan Konseling dan Usaha Kesehatan Sekolah
Authors: Datul Isa Qori , Maisyaroh Maisyaroh , Juharyanto Juharyanto , Sunandar Asep 
Published: June 2022

Abstract: This study aims to describe planning, organizing, implementing, and evaluating, and evaluating BK and UKS services. The method used in this study is a qualitative approach with a type of case study research. While the procedure for collecting data in this study uses interview, observation, and documentation techniques. The results obtained from this study are: (1) BK and UKS service planning is carried out at the beginning of the new school year through meetings held by the Principal with the Head of Student Affairs; (2) the parties involved in BK management include the Principal, Head of Student Affairs, Head of Special Services, and BK officers. While, the parties involved in UKS management include the Principal, Head of Student Affairs, Head of Special Services, and UKS officers; (3) the implementation of BK services was carried out through a consultation program with psychologists, Multiple Intelligences tests, parenting clasess, class visits, and home visits. While, the implementation of UKS services is carried out through dental examination programs, general examinations, first aid services, screening, ant surgery, training for tiwisada cadre and initial PMR; and (4) evaluation of BK and UKS services is carried out through year end meetings conducted by the Principal and Head of Student Affairs.
Abstrak: Penelitian ini bertujuan untuk mendeskripsikan perencanaan, pengorganisasian, pelaksanaan, dan evaluasi layanan BK dan UKS. Metode yang digunakan dalam penelitian ini adalah pendekatan kualitatif dengan jenis penelitian studi kasus. Sedangkan prosedur pengumpulan data dalam penelitian ini menggunakan teknik wawancara, observasi, dan dokumentasi. Hasil yang diperoleh dari penelitian ini adalah: (1) perencanaan layanan BK dan UKS dilaksanakan pada awal tahun ajaran baru melalui rapat yang dilaksanakan oleh Kepala Sekolah dengan Kabid Kesiswaan; (2) pihak-pihak yang terlibat dalam struktur organisasi BK antara lain adalah Kepala Sekolah, Kepala Bidang Kesiswaan, Kepala Bagian Layanan Khusus, dan petugas BK. Sedangkan pihak-pihak yang terlibat dalam struktur organisasi UKS antara lain adalah Lurah, Kepala Sekolah, Kepala Bidang Kesiswaan, Kepala Bagian Layanan Khusus, petugas UKS, petugas puskesmas, komite sekolah dan dewan anak; (3) pelaksanaan layanan BK dilaksanakan melalui program konsultasi dengan psikolog, tes MIR (Multiple Intelligences Research), parenting class, kunjungan kelas dan kunjungan rumah. Sedangkan pelaksanaan layanan UKS dilaksanakan melalui program pemeriksaan gigi, pemeriksaan umum, layanan P3K, screening, operasi semut, pelatihan kader tiwisada dan PMR Mula; dan (4) evaluasi layanan BK dan UKS dilaksanakan melalui rapat akhir tahun yang dilaksanakan oleh Kepala Sekolah dan Kepala Bidang Kesiswaan.