bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Itineraries of Solomonia Saburova and Elena Glinskaya
Authors: Korzinin A. L. 
Published: September 2022

Abstract
This article is focused on the pilgrimage travels and the journeys to towns and settlements by So-lomonia Saburova and Elena Glinskaya. The participation of the Grand Princesses of Moscow in different celebrations, formal receptions, weddings, and consecration of churches has been considered. The chrono-logy of the princesses’ departures from Moscow has been considerably clarified. The material sources (pictorial embroidery (“needle painting”) items from gold embroidery shops of the princesses, icons), which had not been previously taken for the study of the princesses’ itineraries, for the first time provided data on the pilgrimage travels of Solomonia Saburova to the monasteries of Suzdal and to the Holy Trinity St. Sergius Monastery, and of Elena Glinskaya to the St. Paphnutius Borovsk Monastery. As a result of studying the itineraries, the author has come to the conclusion that S. Saburova did not take active part in the affairs of state. The first wife of Vasilii III mainly went on pilgrimages, praying for childbearing to the Lord, to the Most Holy Mother of God, and to Russian saints. The itinerary of Elena Glinskaya is characterized by a higher richness and intensity of travels and a frequent change of location compared to the itinerary of her predecessor. Frequent pilgrimages by Elena Vasilyevna and Vasilii III were dictated by praying to God and Russian miracle workers for an heir and by expectations of conception. After the birth of Ivan IV, the schedule of travels to cloisters and the attendance of official celebrations by the Grand Princess did not become less frequent but, on the contrary, even more busy, being evidence of her increased social status and role in the court life. On the death of her husband and in view of her son’s infancy, Elena Glinskaya actually became a regent for Ivan IV from the end of August 1534. From that time she hardly ever departed from Moscow and rarely visited holy places even in the vicinity of the capital so as not to lose control over the internal affairs. The key role of Elena Vasilyevna in politics is demonstrated by her participation with her son Ivan in the negotiations with the Nogai and Kazan ambassadors in 1534–1536, as well as by her guidance, together with the boyars, of suppression of the insurrection of Andrey Staritskii in 1537. One of the additional subjects considered in this publication concerns the debatable issue of Christian double names, the regularities of choosing baptismal (simultaneously dynastic) and secular (with respect to the date of birth) names in representatives of the Moscow Rurik dynasty: Ivan III, Vasilii III, and his sons Ivan IV and Yuri.
A Paradigm Change in Energy Cooperation between Germany and Russia
Authors: Belov V. B. 
Published: September 2022

Abstract
Germany’s transition to a climate-neutral economy, the main parameters of which were determined by the European Green Exchange Rate (December 2019) and clarified in the updated Law on Climate Protection of Germany (June 2021) and the EU Fit-for-55 program (July 2021), leads to the abandonment of the use of primary energy sources, including their importation from Russia. The energy transformation of the German market economy presumed a gradual restructuring of the existing model of German–Russian cooperation in the energy sector, including its transfer to priority cooperation in the field of energy efficiency and renewable energy sources. Brussels and Berlin responded to the special military operation of the Russian Federation on the territory of Ukraine with large-scale economic and political sanctions, which included significant restrictions on the import of Russian coal and oil. At the same time, the German federal authorities outlined the necessity to abandon Russian pipeline gas and petroleum products, as well as the deprivation of ownership of the two main players from the Russian Federation in the German oil and gas market—Gazprom and Rosneft. Their German partners have frozen participation in Russian projects. At the end of February, the certification of the Nord Stream-2 offshore gas pipeline was stopped. Interdepartmental state interaction and scientific and technical cooperation in the energy sector have been terminated. These events indicated the readiness of the government coalition in the short term to replace the previous model of energy cooperation, which has performed well for half a century, and to move to independence from Russian fossil resources and their derivatives. The author analyzes the reasons and content of the current measures taken by Berlin, as well as their medium- and long-term consequences for German–Russian cooperation.
Comparison of short term surgical outcomes of male and female gastrointestinal surgeons in Japan: retrospective cohort study
Authors: Okoshi Kae , Endo Hideki , Nomura Sachiyo , Kono Emiko , Fujita Yusuke , Yasufuku Itaru , Hida Koya , Yamamoto Hiroyuki , Miyata Hiroaki , Yoshida Kazuhiro , Kakeji Yoshihiro , Kitagawa Yuko 
Published: September 2022

AbstractObjectiveTo compare short term surgical outcomes between male and female gastrointestinal surgeons in Japan.DesignRetrospective cohort study.SettingData from the Japanese National Clinical Database (includes data on >95% of surgeries performed in Japan) (2013-17) and the Japanese Society of Gastroenterological Surgery.ParticipantsMale and female surgeons who performed distal gastrectomy, total gastrectomy, and low anterior resection.Main outcome measuresSurgical mortality, surgical mortality combined with postoperative complications, pancreatic fistula (distal gastrectomy/total gastrectomy only), and anastomotic leakage (low anterior resection only). The association of surgeons’ gender with surgery related mortality and surgical complications was examined using multivariable logistic regression models adjusted for patient, surgeon, and hospital characteristics.ResultsA total of 149 193 distal gastrectomy surgeries (male surgeons: 140 971 (94.5%); female surgeons: 8222 (5.5%)); 63 417 gastrectomy surgeries (male surgeons: 59 915 (94.5%); female surgeons: 3502 (5.5%)); and 81 593 low anterior resection procedures (male surgeons: 77 864 (95.4%);female surgeons: 3729 (4.6%)) were done. On average, female surgeons had fewer post-registration years, operated on patients at higher risk, and did fewer laparoscopic surgeries than male surgeons. No significant difference was found between male and female surgeons in the adjusted risk for surgical mortality (adjusted odds ratio 0.98 (95% confidence interval 0.74 to 1.29) for distal gastrectomy; 0.83 (0.57 to 1.19) for total gastrectomy; 0.56 (0.30 to 1.05) for low anterior resection), surgical mortality combined with Clavien-Dindo grade ≥3 complications (adjusted odds ratio 1.03 (0.93 to 1.14) for distal gastrectomy; 0.92 (0.81 to 1.05) for total gastrectomy; 1.02 (0.91 to 1.15) for low anterior resection), pancreatic fistula (adjusted odds ratio 1.16 (0.97 to 1.38) for distal gastrectomy; 1.02 (0.84 to 1.23) for total gastrectomy), and anastomotic leakage (adjusted odds ratio 1.04 (0.92 to 1.18) for low anterior resection).ConclusionThis study found no significant adjusted risk difference in the outcomes of surgeries performed by male versus female gastrointestinal surgeons. Despite disadvantages, female surgeons take on patients at high risk. Greater access to surgical training for female physicians is warranted in Japan.
Profiles of frequent emergency department users with chronic conditions: a latent class analysis
Authors: Chiu Yohann Moanahere , Dufour Isabelle , Courteau Josiane , Vanasse Alain , Chouinard Maud-Christine , Dubois Marie-France , Dubuc Nicole , Elazhary Nicolas , Hudon Catherine 
Published: September 2022

ObjectivesFrequent emergency department users represent a small proportion of users while cumulating many visits. Previously identified factors of frequent use include high physical comorbidity, mental health disorders, poor socioeconomic status and substance abuse. However, frequent users do not necessarily exhibit all these characteristics and they constitute a heterogeneous population. This study aims to establish profiles of frequent emergency department users in an adult population with chronic conditions.DesignThis is a retrospective cohort study using administrative databases.SettingAll adults who visited the emergency department between 2012 and 2013 (index date) in the province of Quebec (Canada), diagnosed with at least one chronic condition, and without dementia were included. Patients living in remote areas and who died in the year following their index date were excluded. We used latent class analysis, a probability-based model to establish profiles of frequent emergency department users. Frequent use was defined as having five visits or more during 1 year. Patient characteristics included sociodemographic characteristics, physical and mental comorbidities and prior healthcare utilisation.ResultsOut of 4 51 775 patients who visited emergency departments at least once in 2012–2013, 13 676 (3.03%) were frequent users. Four groups were identified: (1) ‘low morbidity’ (n=5501, 40.2%), (2) ‘high physical comorbidity’ (n=3202, 23.4%), (3) ‘injury or chronic non-cancer pain’ (n=2313, 19.5%) and (4) ‘mental health or alcohol/substance abuse’ (n=2660, 16.9%).ConclusionsThe four profiles have distinct medical and socioeconomic characteristics. These profiles provide useful information for developing tailored interventions that would address the specific needs of each type of frequent emergency department users.
Exercise training modalities in patients with lung cancer: a protocol for systematic review and network meta-analysis
Authors: Lu Jiaju , Lin Runhong , Zhang Chuchu , Zhang Meng , Wang Yalei , Zhang Yu 
Published: September 2022

IntroductionLung cancer is a common malignancy and a major cause of cancer-related deaths worldwide, ranking high in terms of morbidity and prevalence. Exercise is a well-established recovery aid for many chronic respiratory conditions and lung cancer. However, it is difficult to determine the superiority of different exercise training modalities using randomised controlled trials (RCTs) or pairwise meta-analyses. Our Bayesian network meta-analysis (NMA) aimed to compare the impact of different perioperative exercise training modalities on lung function, exercise capacity, adverse events, health-related quality of life and mortality in patients undergoing lung cancer surgery, including preoperative and postoperative patients.Methods and analysisWe will perform a comprehensive literature search using PubMed, EMBASE, Cochrane Library and Web of Science, from inception to May 2022, to identify studies that potentially provide data regarding exercise training modalities for patients with lung cancer. We will assess the risk of bias according to the Cochrane risk-of-bias tool and certainty of evidence for the main outcomes using the Grading of Recommendations Assessment, Development and Evaluation framework. Pairwise meta-analyses will be conducted using a random effects model and Stata software, and the NMA will be analysed using R software.Ethics and disseminationEthical approval and patient consent were not required because this study was a meta-analysis of published RCTs. The results of this study are submitted to a peer-reviewed journal for publication.PROSPERO registration numberCRD42021278923.
Assessing the sensibility and utility of a short-form version of the HIV Disability Questionnaire in clinical practice settings in Canada, Ireland and the USA: a mixed methods study
Authors: O'Brien Kelly K , Solomon Patricia , Carusone Soo Chan , Erlandson Kristine M , Bergin Colm , Bayoumi Ahmed M , Hanna Steven E , Harding Richard , Brown Darren A , Vera Jaime H , Boffito Marta , Murray Carolann , Aubry Rachel , O'Shea Noreen , St Clair-Sullivan Natalie , Boyd Mallory , Swinton Marilyn , Torres Brittany , Davis Aileen M 
Published: September 2022

ObjectivesThe Short-Form HIV Disability Questionnaire (SF-HDQ) was developed to measure the presence, severity and episodic nature of health challenges across six domains. Our aim was to assess the sensibility, utility and implementation of the SF-HDQ in clinical practice.DesignMixed methods study design involving semistructured interviews and questionnaire administration.ParticipantsWe recruited adults living with HIV and HIV clinicians in Canada, Ireland and the USA.MethodsWe electronically administered the SF-HDQ followed by a Sensibility Questionnaire (face and content validity, ease of usage, format) and conducted semistructured interviews to explore the utility and implementation of the SF-HDQ in clinical practice. The threshold for sensibility was a median score of >5/7 (adults living with HIV) and>4/7 (HIV clinicians) for ≥80% of items. Qualitative interview data were analysed using directed content analysis.ResultsMedian sensibility scores were >5 (adults living with HIV; n=29) and >4 (HIV clinicians; n=16) for 18/19 (95%) items. Interview data indicated that the SF-HDQ represents the health-related challenges of living with HIV and other concurrent health conditions; captures the daily episodic nature of HIV; and is easy to use. Clinical utility included measuring health challenges and change over time, guiding referral to specialists and services, setting goals, facilitating communication and fostering a multidisciplinary approach to care. Considerations for implementation included flexible, person-centred approaches to administration, and communicating scores based on personal preferences.ConclusionsThe SF-HDQ possesses sensibility and utility for use in clinical settings with adults living with HIV and HIV clinicians in three countries.
Strengthening Care for Children (SC4C): protocol for a stepped wedge cluster randomised controlled trial of an integrated general practitioner-paediatrician model of primary care
Authors: Khano Sonia , Sanci Lena , Woolfenden Susan , Zurynski Yvonne , Dalziel Kim , Liaw Siaw-Teng , Boyle Douglas , Freed Gary L , Moore Cecilia , Hodgins Michael , Le Jane , Morris Tammy Meyers , Germano Stephanie , Wheeler Karen , Lingam Raghu , Hiscock Harriet 
Published: September 2022

IntroductionAustralia’s current healthcare system for children is neither sustainable nor equitable. As children (0–4 years) comprise the largest proportion of all primary care-type emergency department presentations, general practitioners (GPs) report feeling undervalued as an integral member of a child’s care, and lacking in opportunities for support and training in paediatric conditions. This Strengthening Care for Children (SC4C) randomised trial aims to evaluate a novel, integrated GP-paediatrician model of care, that, if effective, will improve GP quality of care, reduce burden to hospital services and ensure children receive the right care, at the right time, closer to home.Methods and analysisSC4C is a stepped wedge cluster randomised controlled trial (RCT) of 22 general practice clinics in Victoria and New South Wales, Australia. General practice clinics will provide control period data before being exposed to the 12-month intervention which will be rolled out sequentially each month (one clinic per state) until all 22 clinics receive the intervention. The intervention comprises weekly GP-paediatrician co-consultation sessions; monthly case discussions; and phone and email paediatrician support, focusing on common paediatric conditions. The primary outcome of the trial is to assess the impact of the intervention as measured by the proportion of children’s (0–<18 years) GP appointments that result in a hospital referral, compared with the control period. Secondary outcomes include GP quality of care; GP experience and confidence in providing paediatric care; family trust in and preference for GP care; and the sustainability of the intervention. An implementation evaluation will assess the model to inform acceptability, adaptability, scalability and sustainability, while a health economic evaluation will measure the cost-effectiveness of the intervention.Ethics and disseminationHuman research ethics committee (HREC) approval was granted by The Royal Children’s Hospital Ethics Committee in August 2020 (Project ID: 65955) and site-specific HRECs. The investigators (including Primary Health Network partners) will communicate trial results to stakeholders and participating GPs and general practice clinics via presentations and publications.Trial registration numberAustralia New Zealand Clinical Trials Registry 12620001299998.
Protocol for the implementation evaluation of an integrated paediatric and primary care model: Strengthening Care for Children (SC4C)
Authors: Hodgins Michael , Zurynski Yvonne , Burley Jade , Pelly Rachel , Hibbert Peter D , Woolfenden Susan , Le Jane , Germano Stephanie , Khano Sonia , Morris Tammy Meyers , Wheeler Karen , Hiscock Harriet , Lingam Raghu 
Published: September 2022

IntroductionImplementation evaluations provide insight into how interventions are delivered across varying contexts and why interventions work in some contexts and not in others. This manuscript outlines a detailed protocol of an implementation evaluation embedded in a stepped-wedge cluster randomised controlled trial of a model of care, Strengthening Care for Children (SC4C), that integrates paediatric care in general practice. The purpose of this manuscript is to describe the pragmatic methods that will be used to capture implementation evaluation process and outcome data within this trial.Methods and analysisOur implementation evaluation will use a mixed methods design, with data collected in the intervention arm of the SC4C trial guided by a logic model developed using the Consolidated Framework for Implementation Research (CFIR) and Proctor and colleague’s taxonomy of implementation outcomes. Data collection will be via questionnaires and semistructured interviews with general practitioners, paediatricians, general practice administrative staff and children and families. Each of the 21 general practices recruited into the study will be described in terms of staffing, patient throughput and location, in addition to the nuanced inner and outer contexts, use of the intervention and its acceptability. We will quantify implementation effectiveness in each general practice clinic using the CFIR validated scoring system. Importantly, we have embedded data collection post intervention to enable assessment of the sustainable adoption of the intervention. An inductive approach to the analysis of qualitative data will identify additional emerging themes that may not be covered by the formal frameworks underpinning our analysis.Ethics and disseminationEthical approval was granted by the Royal Children’s Hospital Ethics Committee in August 2020 (HREC: 65955). Results will be submitted for publication in peer-reviewed journals and presented at relevant conferences.Trial registration numberAustralia New Zealand Clinical Trials Registry 12620001299998 on 1 December 2020.
Team approach to fall reduction in paediatric ward of national referral hospital, Thimphu, Bhutan: a quality improvement initiative
Authors: Chhetri Kalpana , Rinchen Ugyen , Lamichaney Gitanjali , Kinley Bhutan , Dorji Sangay 
Published: September 2022

Falls are common and preventable adverse events that occur in a hospital setting. Falls can cause pain, damage, increase cost and mistrust in the health system. Inpatient fall is a multifactorial event which can be reduced with multistrategic interventions.In this project, we aimed to reduce the fall rate in paediatric ward of Jigme Dorji Wangchuck National Referral Hospital, Bhutan by 25% from the baseline over a period of 6 months by focusing on fall risk assessment, staff education on fall prevention measures and devoting more attention to patients at high risk of fall.We tested three sets of interventions using the Plan–Do–Study–Act approach. For the first cycle, emphasis was on staff education in terms of proper use of fall risk assessment form, risk categorisation and fall prevention advice. In the second cycle, in addition to the first we introduced the ‘high risk of fall package’ and the third cycle focused on early and easy identification of high-risk patients by continuous fall risk assessment and use of high risk of fall sticker.We observed that at the start of the quality improvement project despite our intervention the fall rate of our ward went up but as we continued adding more ideas focusing on high risk patients, we could achieve a fall reduction of 49.3% from the base line by end of third cycle. Our ward saw fall free days of almost 90 days at the end of project.We conclude that inpatient falls occur due to multiple factors therefore a multi-pronged strategy is needed to prevent it. One of the prime preventive strategy is identifying patients who are at high risk of fall and concentrating attention to those patients.
Opioids in advanced cancer: use, storage and disposal in the home
Authors: Mercadante Sebastiano , Adamoli Lucia , Bellavia Giuseppe , Castellana Luisa , Favara Tommaso , Insalaco Lavinia , Mauceri Marco , Scibilia Carla , Lo Mauro Mario , Lo Cascio Alessio , Casuccio Alessandra 
Published: September 2022

ObjectivesTo determine the patterns of storing, using and disposing of opioids among patients with advanced cancer followed at home.MethodsPatients who were prescribed opioids were selected. Prescribed opioids and their doses used for background pain and breakthrough pain were collected, as well as CAGE (cut down, annoyed, guilty and eye opener) for alcohol and drugs, smoking and history of illicit substance use. Questions regarding the opioid use, storage and disposal were posed.Results100 patients were surveyed. Fifty-one patients had unused opioids at home, 25 patients did not throw away the drugs, 40 patients saved opioids for future use and 35 patients were unaware of proper opioid disposal methods. A total of 28 patients reported unsafe use by sharing or losing their opioids; 12 patients were unaware that their opioid could be fatal when taken by others. Most patients acknowledged that pain medications could be dangerous when taken by others. Patients with a partner and who were married were more likely to keep their opioids locked (p=0.028 and p=0.025, respectively).ConclusionA large number of patients with advanced cancer followed at home do not store, use and dispose of opioids safely. Patient education programmes should be incorporated to decrease the availability of opioids at home for abuse, diversion, and accidental poisoning.