bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing Pre- to Post-COVID-19 Health Disparities Between Black and White Female Connecticut Medicaid Beneficiaries in Behavioral Health Utilization
Authors: Coman Emil , Agresta Thomas , Frazier Willie , Powell Wizdom 
Published: July 2022

Background
Broad health disparities (HDs) persist in Connecticut and the United States between minority and White patients, especially in access to and the utilization of behavioral telehealth services.

Objective
We aimed to determine the geographic distribution of HDs in Connecticut between Black female and White female adults in Medicaid behavioral telehealth utilization in 2019 and 2020.

Methods
We used the following spatial Connecticut data: (1) behavioral health utilization from Medicaid claims, from the Connecticut Department of Social Services, for the third quarters of 2019 and 2020; (2) mental health and drug and alcohol treatment facilities and ZCTA (ZIP Code Tabulation Area)-level descriptors from PolicyMap; and (3) Connecticut ZIP-to-ZCTA crosswalk data. Data were joined spatially, merged, and analyzed using spatial autoregressive models in Stata 17 (with outcome, predictors, and errors spatial lags). We computed ZCTA-level HDs comparing Black and White adult female Medicaid beneficiaries’ rates of face-to-face and telehealth behavioral services utilization. Spatial regressions were used to test spatial effects, which are extensions of classic regressions, that add neighbors’ effects to covariates.

Results
Distances to nearest treatment facility vary quite widely in Connecticut by ZCTAs, from 0.06 mile to 13.4 miles—3.5 miles on average. The overall White female versus Black female HDs in behavioral health care utilization were impacted by the distance to the nearest facility, such that ZCTAs farther away from the nearest facility display larger Black versus White HDs—nearly statistically significant effect in 2019 and significant effect in 2020. In 2020, in ZCTAs situated farther away from treatment facilities, both White female and Black female Medicaid patients had higher telebehavioral health utilization (spatial effects +1.3% points and +2.0% points, respectively, for 1 more mile farther away). The differential Black versus White female HDs in telebehavioral health care utilization were not impacted by distance to nearest facility, according to the total effect (direct and indirect through neighboring ZCTAs; P=.26).

Conclusions
Quantitative analyses indicate broad differences in Medicaid enrollment and the utilization of behavioral health services among Black and White female Medicaid recipients in Connecticut and that these differences were rather stable between 2019 and 2020. It appears that the expansion of telebehavioral health services in 2020 enhanced the access to treatment among residents who were located furthest away from providing facilities.

Conflicts of Interest
None declared.
Top-Funded Companies Offering Digital Health Interventions for the Prevention and Treatment of Depression: A Systematic Market Analysis (Preprint)
Authors: Salamanca-Sanabria Alicia , Castro Oscar , Alattas Aishah , Teepe Gisbert W , Leidenberger Konstantin , Fleisch Elgar , Tudor Car Loraine , Mueller-Riemenschneider Falk , Kowatsch Tobias 
Published: July 2022

BACKGROUND

Digital innovations in the mental health care field provide an opportunity to mitigate the global burden of mental disorders such as depression by facilitating timely, accessible, scalable, and affordable interventions. However, there is little evidence on how much these interventions rely on novel automated approaches, such as conversational agents (CAS), just-in-time adaptive interventions (JITAIs), or low-burden sensing technologies.

OBJECTIVE

Our objectives were: (i) to identify the top-funded companies offering digital health interventions for the prevention and treatment of depression (DHID), (ii) to review DHIDs’ scientific evidence, (iii) to identify which psychotherapy approaches are being used, and (iv) to examine the degree to which these DHIDs include novel automated approaches such as CAs, JITAIs, and low-burden sensing technologies.

METHODS

A systematic search was conducted using two venture capital databases (Crunchbase and Pitchbook) to identify the top 30 funded companies offering DHIDs. In addition, studies related to the DHIDs were identified via scientific databases (PubMed, Cochrane Library, and APA Psych-info) and hand-searching (companies’ websites).

RESULTS

The top-30 funded companies offering DHIDs received total funding of 2’592 billion USD up to February 2022. A total of 83 studies were identified by fewer than half of the companies (n=14; 46.6%), of which only 8 (n= 26.6%) employed a randomized controlled trial design. Cognitive-behavioural therapy is the most commonly used psychotherapy approach (n=25, 83.3%), whereas behavioural activation and/or interpersonal therapy (the most effective interventions for depression) were used by only 8 companies (26.6%).	Regarding novel technologies, only a few companies incorporated the use of CAs (n=8, 26.6%), or low-burden sensing technologies such as biofeedback-based breathing training with heart rate measurements (n=3, 10%), and only one used a biomarker for depression based on voice features (3.33%).

CONCLUSIONS

Findings suggest that the amount of funding is not related to the evidence. There is a strong variation in the quantity of evidence provided and an overall need for more rigorous effectiveness trials. Few DHIDs use automated approaches such as CAs and JITAIs, limiting their scalability and delivery of actionable support at the most opportune moments.

CLINICALTRIAL

N/A
Gender Determination Using Nasofacial Anthropometry in the Iranian Population
Authors: Ebrahimi Babak , Ghaffari Neda , Alizamir Tahereh , Rahimi Jaberi Khojaste , Nazmara Zohreh 
Published: July 2022

Objectives: The aim of this study is to predict the gender among Iranian population by determining the facial and nasal indices.
Methods: Four hundred healthy individuals including 200 males and 200 females (age range of 20-25 years) with normal craniofacial configuration took part in the present study. Facial and nasal variables including facial length (FL), facial width (FW), facial index (FI), nasal length (NL), nasal height (NH), nasal width (NW), and nasal index (NI) measured and SPSS 22.0 software was used for statistical analysis.
Results: The mean age was 22.16±2.44 years. The mean FL, FW, FI, NL, NW, and NI were 11.53±0.592 cm, 12.54±1.41 cm, 92.67±6.24 cm, 6.02±0.53 cm, 2.78±0.25 cm, and 90.79±8.22 cm, respectively. There were significant differences in the mean value of all nasofacial parameters (P<0.05). The most prominent face and nose types were hyperleptoprosopic (46%) and platyrrhine (57.75%) among Iranian population. The highest sensitivity and specificity to predict the gender dimorphism were related to FL and FW (.990 and 0.97) and (.970 and 0.94), respectively.
Conclusion: Nasofacial parameters such as FL and FW that are able to sexual dimorphism with high sensitivity and specificity can be helpful in forensic medicine. Also, the nasofacial parameters are useful in in reconstructive, and aesthetic surgeries.
Sábato, Hilda. Repúblicas del Nuevo Mundo: el experimento político latinoamericano del siglo XIX. (Buenos Aires: Taurus, 2021)
Authors: Contreras Gallegos Luis Fernando 
Published: July 2022

El siglo XIX puede ser considerado como el umbral histórico en el que comenzaron a tomar forma los procesos políticos, institucionales y sociales que dieron cuerpo a la modernidad Occidental. Las rupturas que se vivieron en dicho proceso histórico no solo afectaron al viejo continente, pues las revoluciones migraron y tuvieron repercusiones en todo el mundo. Más aún, sería imposible decir que los origenes de este siglo convulso son exclusivamente europeos. Las revueltas, las revoluciones y los descontentos sociales e intelectuales emanaron de diferentes latitudes continentales. La independencia de los Estados Unidos, la Revolución Haitiana y Revolución Francesa dan fe de la compleja geografía a partir de la cual se comenzó a fisurar el Antiguo Régimen. De la misma manera, es importante subrayar que los estímulos ocasionados por estas crisis no se asentaron de la misma manera en todos los territorios. Las situaciones particulares y de contexto de cada espacio determinaron la forma de las transformaciones, de los actores y de los conflictos. A pesar de que sí pueden ubicarse patrones generales y globales de cambio, no es pertinente pretender que estos se vivieron de la misma manera en todos lados.
En ese sentido, el libro de Hilda Sabato, Repúblicas del Nuevo Mundo, es un excelente aporte a las discusiones académicas sobre las transformaciones y las novedades que implicó el siglo XIX. A la autora le preocupa específicamente los experimentos políticos que comenzaron a tener lugar en America tras el colapso de la Monarquía Hispánica y la adopción de distintas formas de autogobierno republicano. Sin embargo, como ella menciona, su interés es dimensionar estas experimentaciones en un contexto de transformaciones políticas globales.
Potensi Senyawa Antibakteri Daging Buah dan Kulit Nanas Sebagai Hand Sanitizer Alami: Literature Review
Authors: Asngad Aminah , Damayanti Friska Wahyu 
Published: July 2022

Penggunaan hand sanitizer untuk menjaga kebersihan tangan sangat penting untuk menghindari berbagai penyakit akibat infeksi oleh bakteri pathogen. Sediaan hand sanitizer seperti alkohol dan triklosan sangat berbahaya jika digunakan secara terus-menerus. Buah dan kulit nanas memiliki senyawa antibakteri yang dapat dijadikan sebagai sediaan hand sanitizer. Tujuan dari literature review ini adalah untuk mengetahui potensi senyawa antibakteri daging buah dan kulit nanas sebagai hand sanitizer alami. Metode studi literatur ini dibuat dengan menganalisis artikel-artikel hasil penelitian yang dipublikasi pada tahun 2016 sampai 2020. Data didapat dengan menggunakan kata kunci pada beberapa search engine Google Scholar, PubMed, dan Garuda. Hasil studi literatur ini didapatkan sebanyak 14 artikel yang sesuai dengan kriteria inklusi dan eksklusi. Hasil analisis review artikel menunjukkan bahwa buah dan kulit nanas memiliki senyawa metabolit sekunder berupa flavonoid, tannin, alkaloid, steroid dan terpenoid serta bromelain sebagai zat antimikroba. Ekstrak buah dan kulit nanas dapat menghambat pertumbuhan bakteri gram positif dan gram negatif yaitu, Escherichia coli, Staphylococcus aureus, Salmonella thypii, Xanthomonus, Bacillus subtilis, Azotobacter, Pseudomonas, Klebsiella, Pseudomonas aeruginosa, Vibrio cholera dan K. pneumoniae. Kesimpulan menunjukkan bahwa kulit nanas lebih potensial dijadikan sebagai sediaan sediaan hand sanitizer alami dibandingkan dengan daging buahnya karena memiliki senyawa antibakteri yang kuat terhadap bakteri pathogen dan memiliki pH yang baik untuk kulit.
Pengembangan Modul Matematika Berbasis Model Pembelajaran Problem Based Learning pada Materi Sistem Persamaan Linier Dua Variabel Kelas VIII SMP/MTs
Authors: Lestari Novita Yuliazmar , Revita Rena , Irma Ade 
Published: July 2022

Penelitian ini bertujuan untuk mengembangkan dan menghasilkan modul pembelajaran matematika berbasis model problem based learning pada materi Sistem Persamaan Linier Dua Variabel yang memenuhi kriteria valid, praktis dan efektif. Desain penelitian yang digunakan pada penelitian ini adalah model ADDIE (Analysis, Design, Development, Implementation, Evaluation). Jenis penelitian ini merupakan penelitian pengembangan (Research and Development). Teknik pengumpulan data yang digunakan berupa tes, angket, observasi, dokumentasi dan wawancara. Teknik analisis data yang digunakan adalah teknik analisis deskriptif kualitatif dan kuantitatif. Hasil penelitian menunjukkan bahwa berdasarkan uji validitas, modul matematika berbasis model problem based learning dinyatakan sangat valid dengan persentase tingkat kevalidan 91,80%. Hasil uji kepraktisan kelompok kecil dengan jumlah responden 10 orang siswa diperoleh bahwa modul matematika berbasis model problem based learning sangat praktis dengan persentase tingkat kepraktisan 85,85%.
Efektifkah Pembelajaran Matematika di Kelas IX SMPIT Cahaya Hati pada Era New Normal ?
Authors: Saleh Rahmad , Aniswita Aniswita , Aprison Wedra , Fitri Haida 
Published: July 2022

Penelitian ini dilatarbelakangi hasil wawancara dan observasi yang dilaksanakan di kelas IX SMPIT Cahaya Hati tentang proses pembelajaran matematika pada era new normal. Proses Pembelajaran dilakukan dengan tatap muka, namun taat protokol kesehatan guna mencegah penularan Covid-19. Waktu setiap pertemuan pembelajaran matematika disetiap pertemuan berkurang jadi 60 menit. Penelitian ini bertujuan mengetahui efektif atau tidak pembelajaran matematika kelas IX SMPIT Cahaya Hati pada era new normal TA 2021/2022. Penelitian ini adalah penelitian kuantitatif deskriptif. Populasi penelitian ialah seluruh peserta didik dan guru mata pelajaran matematika kelas lX SMPIT Cahaya Hati. Teknik pengumpulan data dalam penelitian ini menggunakan lembar observasi, kuesioner dan dokumentasi. Lembaran observasi digunakan untuk mengetahui proses pengelolaan pelaksanaan pembelajaran dan proses pembelajaran komunikatif matematika. Kuesioner digunakan untuk mengetahui bagaimana respon dan aktivitas peserta didik pada pembelajaran matematika. Teknik pengumpulan data melalui dokumentasi untuk hasil belajar peserta didik. Penelitian ini memakai lima indikator, pembelajaran disebut efektif apabila seluruh indikator minimal berkriteria baik. Hasil penelitian menunjukkan bahwa pengelolaan pelaksanaan pembelajaran dan proses pembelajaran komunikatif terlaksana dengan sangat baik, respon dan aktivitas peserta didik tergolong baik, namun hasil belajar peserta didik masih rendah. Hal ini menunjukan jika pembelajaran matematika era new normal di kelas IX SMPIT Cahaya Hati belum efektif.
Interpretasi kata Sulthan (Kajian Ma’na Cum Maghza Terhadap Q.S. Ar-Rahman (55): 33)
Authors: Wijaya Roma , Malikah Siti Sholihatun 
Published: July 2022

AbstractThe Qur'an with all the words and sentences in it always gives birth to a double meaning. In accordance with the point of view, the approach used is the interpreter or reader. One of the words reviewed is sulthan, because the word contains variations in meaning depending on the syntax of the sentence before and after and the context that accompanies it. Therefore, this study reveals the meaning of the word sulthan from the verse Q.S. Ar-Rahman (55): 33. The theoretical approach used is the theory of ma'na cum maghza which was pioneered by Sahiron Syamsuddin as a hermeneutic lighter at UIN Sunan Kalijaga Yogyakarta. With the description-analysis analysis method as well as the primary source in the form of the interpretation of the word sultan from various books of interpretation and also the Qur'an itself. Then secondary sources in the form of studies related to the theme of discussion, either in the form of journals, books, and so on. The results of this study are first, this verse is used as a reference source for the science of astronomy to explore the universe, because it expresses the invitation to penetrate the heavens and the earth. Second, the word sulthan in Surah Ar-Rahman verse 33 describes the power and power of Allah over his supervision of humans and jinn. Third, in depth the Qur'an through Surah Ar-Rahman verse 33 is a proof of Allah's power. AbstrakAl-Qur’an dengan segala kata dan kalimat di dalamnya selalu melahirkan makna ganda. Sesuai dengan sudut pandang, pendekatan yang digunakan mufassir atau pembaca. Salah satu kata yang diulas adalah sulthan, karena kata tersebut mengandung variasi makna tergantung kepada sintaksis kalimat sebelum dan sesudah serta konteks yang menyertainya. Oleh karena itu, penelitian ini mengungkapkan makna kata sulthan dari ayat Q.S. Ar-Rahman (55): 33. Adapun teori pendekatan yang digunakan adalah teori ma’na cum maghza yang dipelopori oleh Sahiron Syamsuddin selaku pemantik hermeneutika di UIN Sunan Kalijaga Yogyakarta. Dengan metode analisis deskripsi-analisis serta sumber primer berupa penafsiran kata sulthan dari berbagai kitab tafsir dan juga al-Qur’an itu sendiri. Kemudian sumber sekunder berupa kajian-kajian yang terkait dengan tema pembahasan, baik berupa jurnal, buku, dan lain sebagainya. Adapun hasil penelitian ini adalah pertama, ayat ini dijadikan sumber rujukan tentang ilmu astronomi untuk menjelajahi alam semesta, karena di dalamnya mengungkapkan dipersilahkannya menembus langit dan bumi. Kedua, kata sulthan dalam surah Ar-Rahman ayat 33 mendeskripsikan tentang kekuatan dan kekuasaan Allah terhadap pengawasannya kepada manusia dan jin. Ketiga, secara mendalam al-Qur’an melalui surah Ar-Rahman ayat 33 ini sebagai bukti kekuasaan Allah Kata Kunci: Interpretasi; Ma’na-Cum-Maghza; QS. ar-Rahman: 33; Sulthan.
STEM-Integrated Flipped Classroom in the Teacher’s Perspective: Could its Implementation in E-Module Improve System Thinking Ability?
Authors: Aspridanel Almira , Abdurrahman Abdurrahman , Lengkana Dewi , Jalmo Tri 
Published: July 2022

This study aims to describe the teacher’s perception of flipped classroom learning strategy using STEM-integrated E-Modules in improving systems thinking ability. The research was conducted in Lampung Province, Indonesia, and was nvolving 50 junior high school science teachers. The method used in this research is mixed methods with Sequential Explanatory Design. Data was retrieved using Questionnaire, and were analyzed using descriptive analysis. The survey results show that teachers have a positive perception of the STEM approach. The results of the analysis also show that most teachers have not used the STEM approach in schools to provide an understanding of science. In addition, teachers also have not implemented STEM-integrated teaching materials.
The Dimensions of Military Engineer Support in the Hybrid War
Authors: Andrei Constantin 
Published: July 2022

Abstract
Hybrid warfare as a new form of politico-military aggression, brings to the fore a complex of conventional and unconventional civil and military actions and operations designed to attack all components of the aggressed state. An appropriate response to the challenges posed by this new type of conflict involves a comprehensive approach, integrating both civilian and military instruments. However, military structures retain a particularly important role in achieving the objectives of the campaign, they possess those capabilities relevant to stabilizing the security environment as well as post-conflict reconstruction. The military engineer support, an important component of any joint military operation, contributes, beyond the fulfillment of missions / tasks in the field, mobility, countermobility, survivability or general support of the assembled military force, to the return to normalcy of the affected society of a conflict. Viewed from this perspective, it can be said that the military engineer support acquires a multidimensional character, which mainly refers to the security, economic, social and educational dimensions.
Comparative Analysis of the Risk of Explosion Generated By Civil Explosives in Industrial Places for Storage of Explosive Materials
Authors: Burdea Monica Crinela , Moraru Roland Iosif , Burdea Florin Ionel , Dregan Cătălin Valentin 
Published: July 2022

Abstract
The fulfillment of the obligations provided by the legislation in force regarding the minimization of risks specific to industrial sites for the storage of explosive materials is a desideratum assumed by the management at the highest level. To this end, the paper aims to provide a brief description of the algorithm for assessing the risk of explosion and establishing the optimal solutions to minimize it, starting from the analysis of concrete situations in few locations from Romania.
Methodology for Analysis, Assessment and Classification of Major-Accident Hazards (Explosion) in the Case of Explosives Depots
Authors: Burdea Monica Crinela , Moraru Roland Iosif , Burdea Florin Ionel , Dregan Cătălin Valentin 
Published: July 2022

Abstract
This paper presents a methodology for the analysis, assessment and classification of explosive hazards in the case of landfills, including the quantification of possible effects on neighborhoods and on human health and the environment.
The Design, Practical Realization and the Programming of a Didactical MB-UGV-1 Mini Crawler Robot Prototype for Engineering Operations
Authors: Murar Bogdan-Ionuț , Petrişor Silviu-Mihai 
Published: July 2022

Abstract
The authors of this scientific paper would like to highlight some didactic-applied contributions regarding the design and the programming of an MB-UGV-1 robotic technological tracked product intended for engineering missions. The following aspects are highlighted: the presentation of the main organological elements from the mechanical structure of the tracked mini-robot, aspects regarding the command and programming elements of the technological product, the advantages and the disadvantages it has. The originality of this paper consists in the following elements: the manner of assembling the organological elements on the mechanical structure of the product, the writing of a program specific to and necessary for the mobility of each degree of freedom associated with the mechanism generating trajectories, the possibility of implementing the mini-robot in didactical applications.
Stem cell therapy in lupus
Authors: Yuan Xinran , Sun Lingyun 
Published: July 2022

Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disease with multiple organs and systems involved such as the kidney, lung, brain and the hematopoietic system. Although increased knowledge of the disease pathogenesis has improved treatment options, current immunosuppressive therapies have failed to prevent disease relapse in more than half of treated patients. Thus, the cell replacement therapy approach that aims to overcome adverse events of traditional treatment and improve recovery rate of refractory SLE is considered as an alternative treatment option. A large number of animal studies and clinical trials have shown stem cell therapy to be a promising therapeutic approach for the treatment of SLE. Since the first transplantation into human patients, several stem cell types have been applied in this field, including hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). In this review, we overview different cell sources of stem cells and applications of the stem cell therapy for treatment of SLE, as well as the comparison between HSCs transplantation (HSCT) and MSCs transplantation (MSCT).
Inflammatory bowel disease: focus on enteropathic arthritis and therapy
Authors: Barkhodari Amir , Lee Kate E. , Shen Min , Shen Bo , Yao Qingping 
Published: July 2022

Abstract
Inflammatory bowel disease (IBD) is a chronic inflammatory disease primarily affecting the gastrointestinal (GI) tract and other organs. In this article, we provide a comprehensive review of IBD, particularly in the context of enteropathic arthritis and its therapeutic advances. Patients with IBD present with intestinal and extraintestinal manifestations (EIMs). Enteropathic arthritis or arthritis associated with IBD (Crohn's disease [CD] and ulcerative colitis [UC]) is the most common EIM and can involve both peripheral and axial joints with some overlaps. Furthermore, peripheral arthritis can be divided into two subcategories. Due to its varied inflammatory presentations and association with NOD2 mutations, CD can mimic other autoimmune and autoinflammatory diseases. Differential diagnosis should be extended to include another NOD2-associated disease, Yao syndrome. Therapy for IBD entails a myriad of medications and procedures, including various biologics targeting different pathways and Janus kinase (JAK) inhibitors. A better understanding of the therapeutic efficacy and mechanism of each drug aids in proper selection of more effective treatment for IBD and its associated inflammatory arthritis.