bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impacts of Dissolved Ni2+ on the Solid Electrolyte Interphase on a Graphite Anode
Authors: Xu Hanying , Li Zhanping , Liu Tongchao , Han Ce , Guo Chong , Zhao He , Li Qin , Lu Jun , Amine Khalil , Qiu Xinping 
Published: April 2022

AbstractTransition metal (e.g. Ni) ions dissolved from layered‐structured Ni‐rich cathodes can migrate to the anode side and accelerate the failure of lithium‐ion batteries. The investigations of the impact and distribution of Ni species on the solid electrolyte interphase (SEI) on the anode are crucial to understand the failure mechanism. Herein, we used time‐of‐flight secondary ion mass spectroscopy (TOF‐SIMS) coupled with multivariate curve resolution (MCR) analysis to intuitively characterize the distribution of Ni species in the SEI. We find that the SEI on the graphite electrode using an EC‐based electrolyte exhibits a multi‐stratum structure. During accelerated aging of the LiNi0.88Co0.08Mn0.04O2/graphite full cell, the dissolution of Ni aggravates significantly upon cycling. A strong correlation between the dissolved‐Ni and organic species in the SEI on graphite is illustrated. The ion‐exchange reaction between Ni2+ and Li+ ions in the SEI is demonstrated to be the main reason for the increase of SEI resistivity.
Das Tris(pentafluorophenyl)methylium‐Kation: Isolation und Reaktivität
Authors: Hoffmann Kurt F. , Battke David , Golz Paul , Rupf Susanne M. , Malischewski Moritz , Riedel Sebastian 
Published: April 2022

AbstractIn dieser Arbeit präsentieren wir zwei verschiedene Synthesewege für das perfluorierte Trityl‐Kation, welche das Handhaben dieser freien, unkoordinierten Spezies in organischen Lösungsmitteln erstmalig ermöglichen. Der Einsatz des schwach koordinierenden Anions [Al(OTeF5)4]− und dessen Derivate erlauben die Charakterisierung dieser Verbindung mittels NMR‐Spektroskopie und Einkristall‐Röntgenstrukturanalyse. Die außerordentlich hohe Hydrid‐Ionen‐Affinität des Kations wurde durch die Wasserstoff‐Abstraktion von Isobutan demonstriert. Zudem offenbaren Cyclovoltammetrie‐Messungen das Oxidiationspotential dieser Verbindung. Zusätzlich wird dies durch die Reaktion mit Tris(4‐bromophenyl)amin gezeigt, wobei die Bildung des Ammoniumyl‐Radikals, auch bekannt als “Magic Blue”, beobachtet wird.
MXene Analogue: A 2D Nitridene Solid Solution for High‐Rate Hydrogen Production
Authors: Jin Huanyu , Yu Huimin , Li Haobo , Davey Kenneth , Song Taeseup , Paik Ungyu , Qiao Shi‐Zhang 
Published: April 2022

AbstractElectrocatalysts for high‐rate hydrogen evolution reaction (HER) are crucial to clean fuel production. Nitrogen‐rich 2D transition metal nitride, designated “nitridene”, has shown promising HER performance because of its unique physical/chemical properties. However, its synthesis is hindered by the sluggish growth kinetics. Here for the first time using a catalytic molten‐salt method, we facilely synthesized a V−Mo bimetallic nitridene solid solution, V0.2Mo0.8N1.2, with tunable electrocatalytic property. The molten‐salt synthesis reduces the growth barrier of V0.2Mo0.8N1.2 and facilitates V dissolution via a monomer assembly, as confirmed by synchrotron spectroscopy and ex situ electron microscopy. Furthermore, by merging computational simulations, we confirm that the V doping leads to an optimized electronic structure for fast protons coupling to produce hydrogen. These findings offer a quantitative engineering strategy for developing analogues of MXenes for clean energy conversions.
A Light‐Driven Molecular Machine Controls K+ Channel Transport and Induces Cancer Cell Apoptosis
Authors: Yang Huiting , Yi Jinhao , Pang Shihao , Ye Kai , Ye Zhicheng , Duan Qi , Yan Zexin , Lian Cheng , Yang Yi , Zhu Linyong , Qu Da‐Hui , Bao Chunyan 
Published: April 2022

AbstractThe design of artificial ion channels with high activity, selectivity and gating function is challenging. Herein, we designed the light‐driven motor molecule MC2, which provides new design criteria to overcome these challenges. MC2 forms a selective K+ channel through a single molecular transmembrane mechanism, and the light‐driven rotary motion significantly accelerates ion transport, which endows the irradiated motor molecule with excellent cytotoxicity and cancer cell selectivity. Mechanistic studies reveal that the rotary motion of MC2 promotes K+ efflux, generates reactive oxygen species and eventually activates caspase‐3‐dependent apoptosis in cancer cells. Combined with the spatiotemporally controllable advantages of light, we believe this strategy can be exploited in the structural design and application of next‐generation synthetic cation transporters for the treatment of cancer and other diseases.
A Novel Catalytic Route to Polymerizable Bicyclic Cyclic Carbonate Monomers from Carbon Dioxide
Authors: Qiao Chang , Shi Wangyu , Brandolese Arianna , Benet‐Buchholz Jordi , Escudero‐Adán Eduardo C. , Kleij Arjan W. 
Published: April 2022

AbstractA new catalytic route has been developed for the coupling of epoxides and CO2 affording polymerizable six‐membered bicyclic carbonates. Cyclic epoxides equipped with a β‐positioned OH group can be transformed into structurally diverse bicyclic cyclic carbonates in good yields and with high selectivity. Key to the chemo‐selectivity is the difference between the reactivity of syn‐ and anti‐configured epoxy alcohols, with the latter leading to six‐membered ring carbonate formation in the presence of a binary AlIII aminotriphenolate complex/DIPEA catalyst. X‐ray analyses show that the conversion of the syn‐configured substrate evolves via a standard double inversion pathway providing a five‐membered carbonate product, whereas the anti‐isomer allows for activation of the oxirane unit of the substrate opposite to the pendent alcohol. The potential use of these bicyclic products is shown in ring‐opening polymerization offering access to rigid polycarbonates with improved thermal resistance.
Phenyl effect on properties evolution of silicone networks under isothermal and dynamic high temperature aging
Authors: Banet Philippe , Chikh Linda , Fouet Thomas , Fichet Odile 
Published: April 2022

AbstractPolysiloxane networks with or without phenyl groups have been subjected to isothermal, thermal sweep and cycling thermal treatments to investigate the phenyl effect on evolution of their properties during thermal aging. Polydimethyldiphenylsiloxanes (PDMDPS) containing between 5 and 30 mol% phenyl groups were more stable than polydimethylsiloxanes (PDMS) under isothermal aging, and no effect of the phenyl content was noted. Hence, only PDMS and PDMDPS with 5 mol% phenyl groups were then retained for the monitoring of their weight loss, tensile stress, elongation at break and Young's modulus during isothermal treatments between 150 and 300°C. Weight losses as well as the cracks appearance time during cycling aging were recorded simultaneously. The activation energies under the different aging conditions were determined, and found equal to 175 kJ/mol from the weight loss (characteristic of the depolymerization reaction) and 145–165 kJ/mol from the mechanical properties (characteristic of the post‐cross‐linking reaction) for PDMDPS, and 110 kJ/mol and 125–145 kJ/mol for PDMS, respectively. These activation energies confirm that silicone containing phenyl moieties are thermally more stable than those without. Finally, all these results empirically allow connecting weight loss and changes in mechanical properties to the appearance of cracks during thermal cycle aging.
Ultraviolet resistance modification of poly(1,3,4‐oxadiazole) fibers by dihydroxyterephthalic acid
Authors: Feng Wenjie , Xie Qibao , Li Wentao , Gao Jian , Liang Jinsong , Jiang Mengjin 
Published: April 2022

AbstractDihydroxyl poly(1,3,4‐oxadiazole) (DHPOD) polymers are synthesized by copolymerization of 2,5‐dihydroxyterephthalic acid (2,5‐DHTA) and terephthalic acid with hydrazine sulfate in oleum, and then DHPOD fibers are prepared by wet‐spinning. The effects of UV irradiation on POD fibers' mechanical properties and surface morphology with and without hydroxyl groups were investigated. As proved by tensile testing and scanning electron microscope measurement, the UV resistance of DHPOD fibers is improved compared to that of p‐POD fibers. Besides, the heat resistance of POD fibers is not damaged by the introduction of phenolic hydroxyl groups. The UV and fluorescence spectra are used to analyze the UV resistance mechanism of the POD containing phenolic hydroxyl groups. Results show that the UV resistance mechanism of DHPOD is related to the proton transfer reaction between the 1,3,4‐oxadiazole ring and ortho phenolic hydroxyl group.
New pyrimidine/thiazole hybrids endowed with analgesic, anti‐inflammatory, and lower cardiotoxic activities: Design, synthesis, and COX‐2/sEH dual inhibition
Authors: Abdel‐Aziz Salah A. , Taher Ehab S. , Lan Ping , El‐Koussi Nawal A. , Salem Ola I. A. , Gomaa Hesham A. M. , Youssif Bahaa G. M. 
Published: April 2022

AbstractSome cyclooxygenase (COX)‐2 selective medications were withdrawn from the market just a few years after their production due to cardiovascular side effects. In this study, a new series of pyrimidine/thiazole hybrids 7a–p was synthesized as selective COX‐2/soluble epoxide hydrolase (sEH) inhibitors with analgesic and anti‐inflammatory effects, and lower cardiotoxicity effects. The target compounds were synthesized and in vitro tested against COX‐1, COX‐2, and sEH enzymes. Hybrids 7j, 7k, and 7i showed the greatest COX‐2‐inhibitory activity and were discovered to be the most potent dual COX‐2/sEH inhibitors. In vivo tests revealed that these hybrids were the most active analgesic/anti‐inflammatory agents, with improved ulcerogenic and cardioprotective properties. Finally, the most active dual inhibitors were docked into COX‐2/sEH active regions to explain their binding mechanisms.
The relationship of types of intuition to thinking styles, beliefs, and cognitions
Authors: Dennin Allyson , Furman Kayla , Pretz Jean E. , Roy Michael M. 
Published: April 2022

AbstractWe argue that intuition is a multifaceted construct, a single label applied to three distinct types of intuition: Holistic, Inferential, and Affective. The goals of this study were to (1) evaluate the independence of these types of intuition and (2) examine the relationships between each type and various thinking styles, beliefs, and cognitions. Results confirmed the distinction among of the types of intuition and established their differential relationships to other relevant constructs including need for cognition, rumination, religiosity, spirituality, conservatism, cognitive reflection, scientific reasoning, and bullshit receptivity. Affective intuition was associated with participants' religious and political beliefs and with lower levels of cognitive reflection and scientific reasoning. Holistic intuition was positively associated with thinking styles such as need for cognition and the propensity to ruminate. Inferential intuition was not strongly related to any of the measures used in this study, perhaps because our tasks did not rely on domain expertise. The results of this study have implications for theory about intuition and on the applications of intuition in areas such as in judgment and decision‐making.
Teaching human anatomy to the visually impaired: A systematic review
Authors: de Lima Paola , Souza e Silva Renata , Guedert Denis Guilherme , Costa Ana Carolina Figueiredo , Gondim Delane Viana , Vale Mariana Lima 
Published: April 2022

AbstractInformation related to human anatomy is present throughout the educational process, especially in undergraduate courses in the biomedical area. These courses have complex theoretical and practical contents, and this becomes more evident when they are developed for the visually impaired. The objective of this work was to perform a systematic review on the teaching of human anatomy for the visually impaired. After the protocol was registered on the PROSPERO platform (CRD42022306002), 10 electronic databases were manually searched with the descriptors “teaching human anatomy” and “visually impaired.” Intervention studies were selected without date or language restrictions. In the end, only eight studies were found. Tactile materials produced manually, and Braille and cadaveric pieces, are assessed as good tools for teaching human anatomy to the visually impaired. There is a pressing need for adaptations of teaching methods to make the teaching more accessible and inclusive.
Synthetic Supramolecular Host for D‐(−)‐Ribose: Ratiometric Fluorescence Response via Multivalent Lectin‐Carbohydrate Interactions
Authors: Fernandes Rikitha S. , Dey Nilanjan 
Published: April 2022

AbstractEasily synthesizable, carbazole‐based organic nanoaggregates have been designed for selective detection of D‐(−)‐ribose at physiological pH. The addition of D‐ribose results in a ratiometric change in fluorescence color from green to cyan (LOD: ∼12 μM). The mechanistic studies indicate the presence of multipoint noncovalent interactions, such as hydrogen bonding and CH⋅⋅⋅π interactions between D‐ribose and acyl hydrazone and terminal pyridyl units of the probe molecule. However, such multipoint interactions dissociate the preformed self‐assembled nanoclusters and induce change in optical response. The probe molecule was further exploited in analyzing D‐ribose content in biological fluids (diluted human urine and blood serum) and oral supplements. The small standard deviation values (2–3.8 %) with nearly quantitative recovery (93.5–105.5 %) indicate the high accuracy of the presented method. Further, low‐cost portable device based coated paper strips were designed for ‘on‐location’ rapid, detection of D‐ribose even at remote locations.
Bioresorbable scaffolds: zebras are not striped horses
Authors: Tarantini Giuseppe , Cardaioli Francesco 
Published: April 2022

Key Points
The magnesium BRS, thanks to their peculiar characteristics, have suggested to be useful in complex clinical scenarios, like bifurcation lesions.
This study shows that the use of magnesium BRS for treating non‐calcified bifurcations is associated with a high rate of scaffold fracture, especially of the proximal stent struts.
While waiting for further evidence, it is reasonable to limit the use of BRS for non‐complex coronary anatomies, avoiding too much aggressive post‐dilation.
Successfully treating the common femoral artery “no go zone” with directional atherectomy plus antirestenotic therapy (DAART)
Authors: Winscott John G. , Hillegass William B. 
Published: April 2022

Key Points
Steno‐occlusive disease of the common femoral artery (CFA) has been historically considered a "no go" and certainly "no stent" zone for endovascular therapy.
Largely a "leave nothing behind" strategy, Directional Atherectomy plus Anti‐Restenotic Theray (DAART) with drug coated balloon (DCB) appears to be a safe and durably effective treatment for CFA steno‐occlusive disease, as well as complex femoropopliteal disease.
Experienced operators safely achieved 84% primary patency and 87% freedom from target lesion revascularization in the CFA with DAART, sufficiently competitive with open endarterectomy to warrant larger randomized trials.
Iso‐osmolar versus low‐osmolar contrast agents to reduce the incidence of renal and cardiovascular side effects
Authors: Kuchibhotla Sudeep , Krajcer Zvonimir 
Published: April 2022

Key Points
Use of iso‐osmolar contrast media (IOCM) versus low‐osmolar contrast media (LOCM) was associated with significantly fewer postoperative cardiac, renal, and limb adverse events in patients identified as high‐risk for acute kidney injury (AKI) undergoing peripheral endovascular interventions for claudication or critical limb ischemia (CLI).

This impactful study promotes the preferential use of IOCM over LOCM in patients with elevated risk of developing contrast‐induced kidney injury who are undergoing endovascular intervention for claudication or CLI.
Double kissing crush stenting: No pain, no gain?
Authors: Dangas George , Garg Aakash 
Published: April 2022

Key Points
Optimal strategy of bifurcation stenting remains debated. Provisional stenting is preferred in most cases.
DK crush stenting has high technical success, however challenges are frequently encountered.
Larger multicenter study comparing DK crush with other two‐stent techniques is needed in the US.
Reaching the optimal volume‐quality balance in transfemoral transcatheter aortic valve replacement
Authors: Gilani Syed , Jneid Hani 
Published: April 2022

Key Points
The current study shows that the mean TF TAVR operator procedural volumes are growing over time, along with the numbers of TAVR procedures and new operators. A significant geographic variation in operators' procedural volumes and density exists.
More than one third of operators in the United States perform ≤10 TF TAVR procedures annually.
Nonocclusive mesenteric ischemia during treatment for ketoacidosis associated with acute‐onset type 1 diabetes mellitus: A case report
Authors: Une Kazunobu , Sumi Yusuke , Kurayoshi Manabu , Nakanuno Ryuichi , Nakahara Masahiro 
Published: April 2022

AbstractThis case report describes a patient with nonocclusive mesenteric ischemia that developed due to diabetic ketoacidosis. We believe that early diagnosis and intervention may improve the prognosis of nonocclusive mesenteric ischemia that has low vascular risk, with the major risk factor being dehydration due to diabetic ketoacidosis.
Blue man: Ochronosis in Otolaryngology
Authors: Dewan Karuna , MacDonald Charles Bruce , Shires Courtney B. 
Published: April 2022

AbstractBlue discoloration of the skin and cartilage, or ochronosis, is a rare physical examination finding. We present two cases of childhood onset ochronosis, one exogenous and one endogenous in etiology. The first was caused by minocycline use for severe acne, and the second was caused by congenital alkaptonuria.
Enhanced Cycling Stability in the Anion Redox Material P3‐Type Zn‐Substituted Sodium Manganese Oxide
Authors: Linnell Stephanie F. , Hirsbrunner Moritz , Imada Saki , Cibin Giannantonio , Naden Aaron B. , Chadwick Alan V. , Irvine John T. S. , Duda Laurent C. , Armstrong A. Robert 
Published: April 2022

AbstractSodium layered oxides showing oxygen redox activity are promising positive electrodes for sodium‐ion batteries (SIBs). However, structural degradation typically results in limited reversibility of the oxygen redox activity. Herein, the effect of Zn‐doping on the electrochemical properties of P3‐type sodium manganese oxide, synthesised under air and oxygen is investigated for the first time. Air‐Na0.67Mn0.9Zn0.1O2 and Oxy‐Na0.67Mn0.9Zn0.1O2 exhibit stable cycling performance between 1.8 and 3.8 V, each maintaining 96 % of their initial capacity after 30 cycles, where Mn3+/Mn4+ redox dominates. Increasing the voltage range to 1.8–4.3 V activates oxygen redox. For the material synthesised under air, oxygen redox activity is based on Zn, with limited reversibility. The additional transition metal vacancies in the material synthesised under oxygen result in enhanced oxygen redox reversibility with small voltage hysteresis. These results may assist the development of high‐capacity and structurally stable oxygen redox‐based materials for SIBs.
Several Key Factors for Efficient Electrocatalytic Water Splitting: Active Site Coordination Environment, Morphology Changes and Intermediates Identification
Authors: Hu Cejun , Hu Yanfang , Zhu Aonan , Li Mingming , Wei Junli , Zhang Yuying , Xie Wei 
Published: April 2022

AbstractWater‐splitting has emerged as a promising alternative strategy to produce clean hydrogen fuel. However, current electrocatalytic water splitting suffers from sluggish kinetics, thus developing efficient electrocatalysts is crucial. Identifying reaction centers discloses the reaction mechanism and will undoubtedly facilitate the design and optimization of efficient water splitting electrocatalysts. This review summarizes several advances involving the identification of the actual active sites and intermediates capture on the catalytic surface. The morphology and valence states change on 2D materials are chose to illustrate how structural evolution affect catalytic activity. Specifically, in situ/ex situ electron microscopy techniques that used for the characterization of catalytic sites, and spectroscopy techniques that used to detect active intermediates at the molecular level are highlighted. In addition, several perspectives, such as the development of new in situ techniques and electrokinetic analysis methods, are emphasized to shed light on future research.
Interplay of Anion‐π+ and π+‐π+ Interactions in Novel Pyrido[2,1‐a]isoquinolinium‐Based AIEgens ‐ Substituent‐ and Counterion‐Dependent Fluorescence Modulation and Applications in Live Cell Mitochondrial Imaging**
Authors: Mule Ravindra D. , Roy Rupam , Mandal Koushik , Chopra Deepak , Dutta Tanoy , Sancheti Shashank P. , Shinde Popat S. , Banerjee Somsuvra , Lal Koner Apurba , Bhowal Rohit , Senthilkumar Beeran , Patil Nitin T. 
Published: April 2022

AbstractRecently, the concept of anion‐π+ interactions has witnessed unique applications in the field of AIEgen development. In this contribution, we disclose a consolidated study of a library of N‐doped ionic AIEgens accessed through silver‐mediated cyclization of pyridino‐alkynes. A thorough photophysical, computational and crystallographic study has been conducted to rationalize the observed substituent‐ and counterion‐dependent fluorescence properties of these luminogens. We further elucidate the prominent role of anion‐π+ interactions, π+‐π+ interactions and other non‐covalent interactions, in inhibiting the undesired ACQ effect. Finally, we have also demonstrated the application of selected AIEgens for imaging of mitochondria in live cells.
Persulfurated Benzene‐Cored Asterisks with π‐Extended ThioNaphthyl Arms: Synthesis, Structural, Photophysical and Covalent Dynamic Properties
Authors: Gahlot Sapna , Gradone Alessandro , Roy Myriam , Giorgi Michel , Conti Simone , Ceroni Paola , Villa Marco , Gingras Marc 
Published: April 2022

AbstractThe synthesis of regioisomeric asterisks (5) and (6) incorporating a benzene core with six 1‐naphthylthio or six 2‐naphthylthio arms are reported in search for new materials with optoelectronic properties. The consequences on the extension of a π system surrounding a persulfurated benzene core provide a new avenue to study the structural, photophysical, and chemical properties of such family of all‐organic phosphors. It also diverts the persulfuration mechanism after two radical cyclizations for making a [5]dithiohelicene by‐product (7) and favors dynamic sulfur component exchange reactions surrounding the core. These exchanges convert asterisks (5) and (6), non‐phosphorescent at 20 °C to the highly phosphorescent (4) (ϕ ∼100 %, solid state at 20 °C). For asterisks (5) and (6), the absence of the typical phosphorescence of the per(phenylthio)benzene core in the solid state at 20 °C and the presence of a weak naphthalene‐based phosphorescence at 77 K is attributed to an energy transfer from the triplet state of the persulfurated benzene core to the outer naphthalene moieties, resulting in an antenna system.