bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving the accuracy of self-reported height and weight in surveys: An experimental study
Authors: Dyke Nina Van , Drinkwater Eric J , Rachele Jerome N 
Published: April 2022

Abstract
Background
Many studies rely on self-reported height and weight. While a substantial body of literature exists on misreporting of height and weight, little exists on improving accuracy. The aim of this study was to determine, using an experimental design, whether the accuracy of self-reported height and weight data can be increased by improving how these questions are asked in surveys, drawing on the relevant evidence from the psychology and survey research literatures.
Methods
Two surveys from two separate studies were used to test our hypotheses (Science Survey, n = 1,200; Eating Behaviours Survey, n = 200). Participants were randomly assigned to one of six conditions, four of which were designed to improve the accuracy of the self-reported height and weight data (“preamble”), and two of which served as the control conditions ( “no preamble”). Four hypotheses were tested: (H1) survey participants read a preamble prior to being asked their height and weight will report lower heights and higher weights than those not read a preamble; (H2) the impact of question-wording (i.e., preamble vs. no preamble) on self-reported weight will be greater for participants with higher BMIs; (H3) the impact of question-wording on height will be greater for older participants; (H4) either version of the weight question – standard or “weight-specific”—may result in participants reporting more accurate self-reported weight. Multivariate analysis of variance was conducted to test Hypothesis 1; two-way ANOVAs were conducted to test Hypothesis 2; moderation analysis was used to test Hypothesis 3; independent samples t-test was conducted to test Hypothesis 4.
Results
None of the hypotheses was supported.
Conclusions
This paper provides an important starting point from which to inform further work exploring how question wording can improve self-reported measurement of height and weight. Future research should explore how question preambles may or may not operationalise hypothesised underlying mechanisms, the sensitivity or intrusiveness of height and weight questions, individual beliefs about one’s height and weight, and survey context.
RNA adenosine modifications related to the prognosis and immune infiltration in osteosarcoma
Authors: Chen Shijie , Zeng Jin , Li PingHuang , Peng Yi , Yan Zuyun , Zhang Aiqian , Zhao Xingping , Li Jun , Zhou Ziting , Wang Sidan , Jing Shengyu , Hu Minghua , Li Yuezhan , Wang Dong , Wang Weiguo , Yu Haiyang , Miao Jinglei , Li Jinsong , Deng Youwen , Li Yusheng , Liu Tang , Xu Dabao 
Published: April 2022

Abstract
Background
RNA adenosine modifications, mediated mainly by the “writer” enzymes (RMWs), play a key role in epigenetic regulation in various biological processes, including tumorigenesis. However, the expression and prognosis role of these genes in osteosarcoma (OS) remains unclear.
Methods
The univariate and multivariate cox analyses were used to construct the RMWs signature in OS using Target datasets. RMWs expression in OS tissue detected by qPCR analysis. Xcell and GSVA were used for the relationship between RMWs and immune infiltration. DGIdb and CMap databases were used for drug prediction. The vivo and vitro experiments showed that strophanthidin elicited the anti-tumor activity against OS.
Results
This study constructed the 3-RMWs (CSTF2, ADAR and WTAP) prognosis signature in OS using the Target dataset, and then verified the risk signature using GEO datasets and independent 63 OS tissues using qPCR analysis. The OS patients with high risk observed poor overall survival, and the prognosis signature was the independent prognostic factor in OS. Functional studies showed that tumor-, metabolism-, cell cycle- and immune-related pathways were related high risk. Next, we found that the RMWs- derived high-risk patients showed increased infiltration of Macrophages M2 and cDCs. Furthermore, we predicted the potential drugs for OS using DGIdb and CMap database. The vivo and vitro experiments showed that strophanthidin elicited the anti-tumor activity against OS via repressing cell growth and inducing cell cycle arrest at the G1 phase.
Conclusion
The 3-RMWs-based prognostic signature established in this study is a novel gene signature associated with immune infiltration, and strophanthidin was identified as a candidate therapy for OS via repressing the growth and cell cycle of OS cells.
An improved sparse identification of nonlinear dynamics with Akaike information criterion and group sparsity
Authors: Dong Xin , Bai Yulong , Lu Yani , Fan Manhong 
Published: April 2022

Abstract
A crucial challenge encountered in diverse areas of engineering applications involves speculating the governing equations based upon the partial observations. On this basis, a variant of the sparse identification of nonlinear dynamics(SINDy) algorithm is developed. First, Akaike information criterion(AIC), which is based on information criterion is integrated to enforce model selection via hierarchically ranking the most informative model from a manageable candidate models. This integration avoids restricting the number of candidate models, which is a disadvantage of the traditional methods for model selection. The subsequent procedure expands the structure of dynamics from ordinary differential equations(ODEs) to partial differential equations(PDEs) when the group sparsity is employed to identify the nonconstant coefficients of partial differential equations. Of practical consideration within an integrated frame is data processing, which tends to make noise separate from signals and inclines to parametrize the noise probability distribution. In particular, the coefficients of a species of canonical ODEs and PDEs, such as the duffing oscillator, Lotka-Volterra, Rössler, Burgers’ equation and Kuramoto-Sivashinsky equation can be identified correctly with the introduction of noise. Furthermore, except for the normal noise, the proposed approach is able to capture the distribution of uniform noise. In accordance with the results of the experiments, the computational speed is markedly advanced and possess robustness.
Digital holographic study of corona wind assisted evaporation of hydrocarbon from a microliter well
Authors: Shukla Digvijay , Mishra Bal Krishan , Panigrahi Pradipta 
Published: April 2022

Abstract
Abstract:
The present study aims to understand the evaporation dynamics of heavy hydrocarbon liquid (cyclohexane) from a circular well cavity under the influence of corona wind. Particle image velocimetry is used to characterize the velocity field of the corona wind generated by a needle and plate configuration. Digital holography interferometry is used to decipher the mole fraction distribution of the vapor cloud. Circular well cavities of radius 2.0, 2.5 and 4 mm are studied. The study explores the effect of corona wind on the modification of vapor phase transport and the evaporation rate from the circular well. The effect of corona wind on the evaporation of different sized well cavities increases with an increase in actuation voltage. The side wall of the cavities influences the distribution of the vapor cloud due to the interaction with the incoming corona wind. More than 10 times enhancement of evaporation is observed at 10 kV excitation voltage setting of the corona wind generator. The corona jet assisted evaporation can be very useful in thin film evaporative cooling for electronics due to its simplicity in design and superior performance.
A survey conducted using health claims records and questionnaires to investigate the prevalence of migraine in Japan
Authors: Sakai Fumihiko , Hirata Koichi , Igarashi Hisaka , Takeshima Takao , Nakayama Takeo , Sano Hiromi , Kondo Hiroyuki , Shibasaki Yoshiyuki , Koga Nobuyuki 
Published: April 2022

Abstract
BackgroundMigraine is a chronic disease characterized by episodic headache attacks. No recent studies have, however been conducted on the epidemiology of migraine or the treatment landscape in Japan. This study was conducted as a fact-finding survey using medical claims receipt data and an online survey on migraine and headaches, conducted among members of health insurance associations with the objective of gaining an understanding of migraine prevalence and the treatment status in Japan.MethodsThe study methodology utilized a unique approach of combined data sources. The data sources used in this study are medical claims receipt data and online survey data provided by DeSC Healthcare Inc (DeSC). The primary outcomes (from survey responses) were: the overall number and proportion of migraine patients; and the overall prevalence of migraine, stratified by age and sex. The secondary outcomes (from survey responses) were use of medical care; and clinical features/headache symptoms. The analysis population included all individuals who had response data for surveys conducted by DeSC. The online survey data and medical claims receipt data were summarized. ResultsThe data population comprised 21,480 individuals. On the basis of the survey results, including probable cases, the overall prevalence of migraine was 3.2%. The highest prevalence of migraine was observed in patients aged 30-39 years. The prevalence of migraine in women was 4.4 times higher than in men. The percentage of migraine patients who had not been seen by a doctor was 81.0%. More than 80% of patients were taking over-the-counter drugs and 4.8% took prescription medicines only. Approximately 52.9% of patients considered that the intensity of pain symptoms was severe. Moreover, the majority of patients (72.9%) considered that the impairment of daily life activities was of moderate or severe degree. ConclusionsIn Japan, the percentage of people with migraine who did not receive medical attention is as high as 80%. Additionally, the majority of patients tend to endure symptoms and continue with everyday activities. With innovative treatment approaches becoming available it is necessary to disseminate information that migraine is not a simple headache but an illness that requires medical treatment and consultation.
WDR74 facilitates TGF-β/Smad pathway activation to promote M2 macrophage polarization and diabetic foot ulcer wound healing
Authors: Kang Geng , Ma Xiumei , Jiang Zongzhe , Gu Junling , Huang Wei , Wang Weiming , Xu Yong , Xu Youhua 
Published: April 2022

Abstract
Diabetes is a serious global health challenge that affects millions of people worldwide. One major complication is diabetic foot ulcer (DFU), leading to decreased quality of life and increased mortality in diabetic patients. The underlying mechanism of DFU is not completely understood. The mechanism involved in wound healing in diabetes was studied in vivo and in vitro. Gain-and loss-of function studies were performed to study the roles that WDR74 and TGF-β play in DFU. M1 and M2 macrophage phenotypic marker, and extracellular matrix (ECM) components, angiogenic makers were determined by RT-qPCR and/or Western blot analysis. Localization of these proteins were determined by immunofluorescence staining and/or immunohistochemistry. Interaction between WDR74 with Smad2/3 in macrophages was detected by co-immunoprecipitation. We found that WDR74 and M2 macrophages were decreased in wound tissues from DFU mice. TGF-β upregulation increased the expression of M2 macrophage markers (arginase-1, and YM1), IL-4, while decreased expression of M1 macrophage marker (iNOS). TGF-β upregulation also increased the production of ECM and promoted the wound closure in diabetic mice. We also noticed that WDR74 overexpression increased Smad2/3 phosphorylation elevated the population of M2 macrophage ECM production, and alleviated DFU. LY2109761 treatment normalized effects of TGF-β or WDR74 overexpression. In conclusion, WDR74 promoted M2 macrophage polarization, leading to improved DFU in mice, through the activation of TGF-β/Smad pathway.
Inflammatory Esophagogastritis and Acute Kidney Injury After Intentional Ingestion of Paraquat
Authors: Gunawan Febrian Juventianto , Halim Risna , Parewangi Andi Muhammad Luthfi , Rasyid Haerani 
Published: April 2022

Abstract
We describe a clinical presentation of Inflammatory esophagogastritis and acute kidney injury in young adult male after intentional ingestion of paraquat. The high number of deaths from paraquat is due to its toxicity and ineffective treatment. Intravenous fluid, immunosuppressant, and antioxidant was given to reduce the effect of toxins on target organs.
How can we optimize the long-term outcome in children with intracranial cavernous malformations? A single-center experience of 61 cases
Authors: Hirschmann Dorian , Czech Thomas , Roessler Karl , Krachsberger Paul , Paliwal Shivam , Ciobanu-Caraus Olga , Cho Anna , Peyrl Andreas , Feucht Martha , Frischer Josa Maria , Dorfer Christian 
Published: April 2022

Abstract
OBJECTIVETo provide a treatment algorithm for pediatric patients with intracranial cavernous malformations (CMs) based on our experience.METHODS Patients <18 years of age who were treated either surgically or conservatively at the authors’ institution between 1982 and 2019 were retrospectively evaluated. RESULTSA total of 61 pediatric patients were treated at the authors’ institution: 39 with lobar CMs, 18 with deep CMs, including 12 in the brainstem and 6 in the basal ganglia, and 4 with CMs in the cerebellar hemispheres. Forty-two patients underwent surgery and 19 were treated conservatively. The median follow-up time was 65 months (1-356 months). In surgically treated patients, lesions were larger (2.4cm vs 0.9cm, p<0.001). In patients with lobar CMs, seizures were more common (72% vs 21%, p=0.003) in the surgery group than in conservatively managed patients. In deep CMs modified Rankin scale (mRS) was higher (4 vs 1, p=0.003) in the surgery group than in conservatively treated patients. At time of last follow-up no differences in Wieser outcome class I was seen (86% vs 67%) in lobar CMs and mRS scores had aligned between the treatment groups in deep CMs (1 vs 0). We encountered no new permanent neurological deficit at time of last follow-up. We propose a treatment algorithm according to lesion location and size, burden of symptoms, epilepsy workup, and further clinical course during observation.CONCLUSIONA conservative management is safe in pediatric patients with asymptomatic CMs. Gross total resection should be the aim in patients with symptomatic lobar CMs. A less aggressive approach with subtotal resection, when required to prevent neurological compromise, sustainably improves neurological outcome in patients with deep CMs.
Curative efficacy of strengthen transfusion strategy for older patients with hip fracture: A Single-center Retrospective Study
Authors: Zhao Yuqi , Guo Junfei , Fu Mingming , Zhang Yaqian , Wang Zhiqian , Hou Zhiyong 
Published: April 2022

Abstract
Background: Perioperative transfusion is very common in older patients with hip fracture, but there is still great controversy about whether patients with hemoglobin (Hb) value between 90-100g/L should receive transfusion. The aim of this retrospective study was to observe the curative efficacy of strengthen transfusion strategy for hip fracture patients of age≥65 years.Methods: A retrospective analysis was made on elderly patients with hip fracture who were treated in a single trauma emergency center from 2015 to 2019. Patients who received surgical treatment and had perioperative transfusion records were selected and were divided into three groups according to the lowest perioperative Hb value of 70-80g/L, 80-90g/L and 90-100g/L. According to whether to continue transfusion when the Hb value is between 90-100g/L, they were divided into strengthen transfusion strategy group or routine transfusion strategy group. The demographic data (gender, age, fracture type, complications, etc.), the Hb value, red blood (RBC)use, and patient outcomes between the two groups were analyzed.Results: In total, 4966 elderly hip fracture patients were identified of whom 22.0% had documented perioperative transfusion. After screening the inclusion and exclusion criteria, a total of 802 patients were included in our study, including 95 in the 70-80g /L group, 264 in the 80-90g /L group and 443 in the 90-100g /L group. There was no significant difference in hospital stay between strengthen and routine transfusion group, however strengthen transfusion strategy can reduce the incidence of perioperative pulmonary infection and cerebral infarction in each group. And it can also reduce the incidence of arrhythmia, urinary tract infection in 80-90g /L group and electrolyte disorder in 90-100g /L group, respectively.Conclusions: For elderly patients with hip fracture, strengthen transfusion strategy does not increase the risk of perioperative major adverse coronary events (MACE), reduce the incidence of adverse outcomes such as perioperative pulmonary infection, cerebral infarction and shorten the length of hospital stay.
Decreased psychiatric symptomatology after the onset of COVID-19 pandemic: A longitudinal college mental health study from Turkey
Authors: Dogan Asli Ercan , Kebapci Dilek , Ertan Oguz , Kalay Zeynepgul , Caki Nurdan Kozan , Sar Vedat , Eser Hale Yapici 
Published: April 2022

Abstract
Objective: COVID-19 pandemic brought significant challenges for college students. This study aimed to investigate changes in psychiatric symptomatology among them compared to the pre-pandemic period alongside their determinants. Methods: Data were collected before and three months after the onset of the pandemic from 168 students who had applied to a college mental health center. Psychiatric symptomatology was assessed by Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7), and Adult Attention Deficit Hyperactivity Disorder Self-Report Scale (ASRS). Possible vulnerability factors were screened by a survey on COVID-19-related health and social isolation status, Fear of COVID-19 Scale, Social Media Use Disorder Scale (SMDS), Distress Thermometer, Scoff Eating Questionnaire, and International Physical Activity Questionnaire Short-Form (IPAQ). Results: PHQ-9, GAD-7 and ASRS scores significantly declined in the follow up. Even though the screen time increased, SMDS scores significantly declined. SMDS had a direct effect on PHQ-9 and ASRS levels, in addition to an indirect effect through Stress Thermometer. Higher SMDS scores predicted higher anxious and depressive symptomatology in repeated assessments. Fear of COVID-19 scores had a direct effect on GAD-7 scores only. Conclusion: This study suggested that stress level and psychiatric symptomatology of the students decreased significantly in the early phases of the pandemic. Level of social media use disorder should be taken into account while following college students with mental health symptoms.
A Comparison between the Enhanced and Express Femoral Workflow for Robot-Assisted Total Hip Arthroplasty: A Self-controlled Observational Study
Authors: Li juncheng , Ni ming , Ji quanbo , Zheng qingyuan , Sun jingyang , Zhang guoqiang 
Published: April 2022

Abstract
Purpose: The aim of this prospected comparison study was to compare the enhanced workflow and express workflow for Mako robot-assisted total hip arthroplasty.Method: From February 2020 to December 2020, 26 patients (43 hips) underwent primary robot-assisted total hip arthroplasty. There were 14 male and 12 female patients. The mean age at surgery was 53.5±13.6 years. The enhanced workflow and express workflow were performed separately in robot-assisted total hip arthroplasty on the same hip. The between-group operating time, hip length change, and combined offset were compared. Differences were considered statistically significant at p<0.05.Result: The operating time with the enhanced and express registrations were 73.3±14.1 minutes and 68.8±12.8 minutes, respectively (p=0.001). The accuracy of the mean hip length change between the intraoperative trailing implantation and preoperative plan were 1.6±6.9 mm and -0.5±3.1 mm, respectively (p=0.029). The accuracy of the mean hip length change between the intraoperative prosthesis implantation and preoperative plan were 0.8±5.4 mm and -0.7±3.2 mm, respectively (p=0.025). Regarding the accuracy of the mean preoperative and intraoperative combined offsets, there were no significant differences between the two registrations (p>0.05). Conclusion: In comparison, the enhanced registration for robot-assisted total hip arthroplasty is more time-consuming than the express registration. However, the enhanced registration is more accurate than the express registration in assessing limb length discrepancy. Both registrations produce the similar accuracy of the combined offset.
Identification, pathogenicity, fungicide sensitivity and biological control of Rhizoctonia solani associated with damping-off disease of sugar beet in Morocco
Authors: Farhaoui Abdelaaziz , Tahiri Abdessalem , Ezrari Said , Radouane Nabil , Khadiri Mohammed , Alami Nabila El , Belabess Zineb , Mohammed Baala , Amiri Said , Lahlali Rachid 
Published: April 2022

Abstract
The fungus Rhizoctonia solani Kühn is an economically important pathogen involved in root rot and seedling damping-off disease of sugar beet (Beta vulgaris L.). In Morocco, this is the first detailed report of R. solani as the causative agent of sugar beet damping-off. The identification of the pathogen was based on combining the morphological characteristics and molecular characterization using the ribosomal DNA internal transcribed spacer (rDNA ITS) region. Antifungal activities of four commercial fungicides; azoxystrobin, difenoconazole, tebuconazole, and trifloxystrobin were assessed in vitro, displaying effective inhibition of the mycelial growth of the pathogen strains using PDA medium. A commercially available Bacillus subtilis Y1336 was evaluated as a potential biological control agent (BCA) against seedling damping-off caused by R. solani. The biological control activities of B. subtilis Y1336 was demonstrated by dual culture bioassays on PDA medium, in vitro seed inoculation with R. solani and B. subtilis, and by applying the BCA as seed coat under greenhouse conditions. This is the first time that the commercially available B. subtilis Y1336 has been proved as an effective BCA against the damping-off disease of sugar beet. This commercial antagonist should be incorporated into the integrated disease management startegy for sugar beet seedling mortality together with effective tested fungicides.