bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcome of urinary tract infection caused by Extended Spectrum Beta-Lactamase (ESBL) producing Escherichia coli and Klebsiella pneumoniae in Dr Zainoel Abidin General Hospital Aceh
Authors: Hayati Zinatul , Jamil Kurnia F. , Azhari Afrianda , Mahdani Wilda , Karmil Teuku Fadrial , Yossadania Asyriva , Dahril Dahril , Habibie Yopie Afriandi 
Published: February 2022

Introduction : Extended-spectrum ?-lactamase (ESBL) is a mutated ?-lactamase enzyme that can hydrolyze beta-lactam antibiotics. The aim of this study was to determine the incidence rate, characteristics of patients, antibiotic use and outcome of urinary tract infections (UTIs) due to ESBL-producing Escherichia coli and Klebsiella pneumoniae at Dr Zainoel Abidin General Hospital Aceh.Method : The samples of this study were all Escherichia coli and Klebsiella pneumoniae isolated from urine culture of UTI cases. Patient characteristics and antibiotic use data were extracted from medical records. UTIs outcome was assessed as clinical improvement or death within a maximum of 30 days of treatment.Result : The results of this study obtained 63 patients with UTIs caused by E. coli and K. pneumonia of which 52.4% of them were ESBL producers. The incidence of UTIs due to E. coli was higher than that of K. pneumoniae, 63.5% and 36.5% respectively. E. coli ESBL producers were more in number than non-ESBL, conversely K. pneumoniae were mostly non-ESBL. The characteristics of patients with UTIs caused by E. coli and K. pneumoniae were predominant women 52.4%, and most cases were at 56-64 years old. Antibiotic therapy that given before and after culture results to UTI patients were generally ceftriaxone. UTIs outcome due to ESBL producing Escherichia coli and Klebsiella pneumoniae showed that 26/33 (78.8%) patients experienced improvement, however, 7/33 (21.2%) patients died.Conclusion : The irrational use of ceftriaxone in patients with UTI caused by ESBL producing E. coli and K. pneumoniae has led to a poor outcome for the patient.
Primary amenorrhoea caused by Turner syndrome: A case series
Authors: Nora Hilwah , Maracilu Cut Nonda , Andalas Mohd , Priyanto Muhammad Hikmawan 
Published: February 2022

Background: Amenorrhea is a condition where women do not experience menstruation or the cessation of menstrual cycles at reproductive age. Amenorrhea is divided into primary and secondary. Turner syndrome is one example of gonadal dysgensis that cause the most common primary amenorrhea. It is represented by the absence of all or part of the normal second sex chromosome and physical features including short stature, webbed neck, cubitus valgus, pterygium colli, low hairline, edema of the hands and feet, and shield chest. Clinical pictures and karyotype of Acehnesse patients with Turner syndrome are presented in this study. The patients involved in the study were those who came to an endocrinology clinic in a tertiary care center.Case Presentation: We reported four cases of Turner syndrome which were confirmed from anamnesis, physical examination and chromosomal analysis at the Department of Obstetrics and Gynecology in the Fertility, Endocrine and Reproductive Division of RSUD Dr. Zainoel Abidin Banda Aceh.Conclusion: All patients with Turner syndrome had amenorrhea, short stature, bone deformity and underdeveloped primary dan secondary sexual characteristic. Only one case has monosomy X (45, XO), a mosaic chromosomal component was present in the rest of them (45, X with mosaicism).
A 10-day-old baby with "lightning-like" myoclonic limb jerks during sleep: a case report
Authors: Hastuti Sri , Maulana Imam , Sofiana Debby , Fathima Raisha 
Published: February 2022

Background: Benign neonatal sleep myoclonus (BNSM) is a condition commonly mistaken for seizures. It is characterized by self-limiting "lightning-like" myoclonic limb jerks that occur primarily during sleep in the newborn phase but are not associated with epilepsy that suddenly stops when the infant is agitated. This condition is potentially resolved between the ages of 2 and 6 months. The incidence of BNSM per 1,000 births is 0.8 to 3 cases. This case report aims to explain the findings of a neonate with multiple episodes of abnormal jerks affecting the entire limb, only during sleep.Case Report: We reported a 40-day-old baby boy with multiple episodes of abnormal jerks affecting the entire limb since 10-day-old only during sleep. The jerky body movements appeared six until nine times a day with approximately an hour interval between movements. The patient did not have any neurologic deficits, pathologic reflexes and vital signs abnormalities. Electroencephalogram (EEG) revealed the normal result. We diagnosed the patient with BNSM.Conclusion: The BNSM is a self-limiting disorder. For neonatal seizures or even neonatal status epilepticus, BNSM can be misinterpreted, recognizing childhood benign sleep myoclonus is important to prevent unnecessary diagnostic studies and treatments. The prognosis was good and the patient didn't need any medication and long-term follow-up.
Comparison between the diagnosis of acne vulgaris by teledermatology and face-to-face consultations
Authors: Rangkuti Anggita Dwi Puteri , Jusuf Nelva Karmila , Putra Imam Budi 
Published: February 2022

Background: Acne vulgaris is a common skin disorder in the pilosebaceous unit that is self-limited, especially in adolescents. Adam Malik Hospital in Medan reported the incidence of acne vulgaris to be 1.10%. Telemedicine has become popular in recent years, especially during the COVID-19 pandemic. SAF teledermatology using digital cameras has also increased patient service satisfaction, promising diagnostic reliability and clinical outcomes similar to face-to-face visits. This study aimed to compare teledermatology's diagnostic test parameters and accuracy and face-to-face consultations in diagnosing acne vulgaris.Methods: This study was an observational analytic study with a cross-sectional design involving 110 suspected acne vulgaris. The characteristics of sex and age were recorded. The resident established the diagnosis of acne vulgaris directly and teledermatologically by the consultant based on photo documentation of 5 facial lesion areas, namely the forehead, chin, right cheek, left cheek, and the entire face, along with the photo with photos from the history submitted by the resident. Diagnostic tests were carried out, including sensitivity, specificity, positive predictive value, negative predictive value, accuracy, and an agreement test.Results: Acne vulgaris was more common in women (76 patients, 69.1%) and patients aged 18-22 years (55 patients, 50%). Of 110 patients, 105 were diagnosed with acne vulgaris by face-to-face consultations and teledermatology. Teledermatology showed 100% sensitivity, specificity, positive predictive value, negative predictive value, and accuracy. The agreement test between teledermatology and face-to-face consultations was 1, indicating favorable agreement.Conclusion: There was no significant difference in the diagnosis of acne vulgaris through teledermatology and face-to-face consultations.
Detecting nurse's personality models with disc
Authors: Aini Qurratul 
Published: February 2022

Background: The personality factor can detect a person's counterproductive behavior. Certain personality types determine a person's work style and the limitations and weaknesses of his performance. One tool used to detect personality types related to work style is the DISC personality model. This study aims to determine the behavioral type of nurses based on the DISC application.Methods: This research used mixed methods. Research design begins with data collection and analysis using quantitative procedures, then continues with data collection and analysis. Quantitative approaches through descriptive analysis implemented a behavioral scale counterproductive and DISC personality profile using the DISC application. The DISC app helps organizations describe personality information, make decisions, and interact with team members and other stakeholders.Results: Characteristics of respondents at Klaten Hospital consisted of 58.8% of respondents aged 20-40 and 41.2% of respondents aged 41.2%. From several respondents, it can be seen that the respondents' behavior is dominant and conscientiousness, with the overall scores, obtained being 38% and 35%. While the scores for the characteristics of influence and stability are 17% and 10%, respectively. Conclusions: Most nurses had dominant and conscientious personalities. The results came from four behavioral dimensions (dominance, influence, steadiness, and conscientiousness).
Spiritual emotional freedom technique increased patient self efficacy
Authors: Maryana Maryana , Dewi Sari Candra 
Published: February 2022

Introduction: Patients with a diagnosis of Diabetes Mellitus (DM) in Sleman Regency in 2020 were 20,097 patients. The treatment of diabetes requires good motivation from patients. Self-confidence or self-efficacy will help shape behaviors that support healing. Spiritual Emotional Freedom Technique (SEFT) was a therapy that can create positive emotional conditions and a calm mind so that the right thoughts emerge to decide attitudes in helping the healing process. This study aims to determine the effect of SEFT for self-efficacy of patients with DM-Type 2 at the working area of public health center Seyegan, Sleman, Yogyakarta, Indonesia.Methods: This study used a quasi-experiment with pre-test post-test using control group design. Patients were assessed pre-test and post-test with the DM-Self Efficacy Scale. The intervention group was subjected to SEFT therapy. The sample of this study was 40 respondents from the intervention group and 40 respondents from the control group. The sampling technique used the purposive sampling technique. Data collection was carried out between July and August 2020.Results: The results of the data collected were processed using the Wilcoxon test and the Mann Whitney test. Wilcoxon test results in the intervention group obtained p = 0.000 (p <0.05) and in the control group obtained p = 0.000 (p <0.05). Mann Whitney test results obtained p = 0.003 (p <0.05).Conclusion: SEFT technique affects the increasing self-efficacy in type II DM patients.
Significance of pulmonary hypertension probability in predicting six-minute walking distance in uncorrected acyanotic grown-up congenital heart disease at Sanglah General Hospital, Bali
Authors: Aditya Putu Sukma Parahita , Dewangga I Made Satria Yudha , Yantie Ni Putu Veny Kartika , Gunawijaya Eka , Wita I Wayan 
Published: February 2022

Background: Pulmonary hypertension may cause impairment of functional capacity, which is a predictor of survival and quality of life in a patient with uncorrected acyanotic grown-up congenital heart disease. A six-minute walking test (6MWT) is a submaximal exercise test to measure these patients' functional capacity. This study aims to determine the significance of echocardiography parameters, such as Pulmonary Hypertension (PH) probability and Mean Pulmonary Artery Pressure (MPAP), as a predictor of functional capacity by 6MWT measurement.Methods: Analytic observational study was used to determined walking distance as a measurement of functional capacity in acyanotic CHD patients. The probability of (PH) and MPAP was obtained from echocardiography and divided into three categories (low, intermediate, and high probability) based on guidelines defined by PH 2015. MPAP measured the d using the pulmonary valve acceleration time formula (90 â€“ 0.62*PVAT). The relationship between 6MWT distance with MPAP and probability of PH was measured using pearson correlation and one-way ANOVA.Â We included 43 patients from the Grown-Up Congenital Heart Disease (GUCH) registry who fulfills the inclusion criteria (age more than 18 years whom defect correction has not been done). All participants were given informed consent. Data were analyzed using SPSS version 20 for Windows.Results: Forty-three patients were included in this study, with 35 females (81.4%) and 8 males with age range 18-75 years old. The most prevalent GUCH was an atrial septal defect (69.8%). Twenty-one (48%) patient was classified as high PH probability. There was a significant difference between the mild probability of PH with intermediate (MD=94.3 meters; p < 0.001) and high probability (MD=141.9 meters; p<0.001). MPAP shows a strong correlation with walking distance (r=-0.68; p<0.001).Conclusion: GUCH patients with high and intermediate PH probabilities from echocardiography had a shorter walking distance and lowered functional capacity.Â MPAP is a reliable measurement to predict 6MWT in these patients.
Faktor risiko kejadian berat bayi lahir rendah di RSUP Sanglah, Denpasar, Bali, Indonesia
Authors: Aryana I Gusti Ngurah Yuda Bagus , Sari Komang Ayu Kartika , Aryani Putu 
Published: February 2022

Introduction: Maternal and child health has become a primary health focus in Indonesia and the maternal and child mortality rate in Indonesia is higher than those in South-East Asia countries. The incidence of Low Birth Weight (LBW) contributes to more than 50% of all neonatal mortality of all births in Indonesia. Therefore, identification of the risk factors that contributes to the incidence of LBW is important.Method: This retrospective case-control study involved 50 cases of LBW and 50 controls (baby with normal birth-weight), The data were analyzed using SPSS version 22.Result: The results of multivariate analysis showed that the factors significantly associated with LBW incidence were maternal blood pressure (p=0.000), history of giving birth to LBW babies (p=0.000), and the mode of current labor (p=0.034). The maternal age, maternal education level, maternal occupation, maternal anemia, parity, history of smoking, history of alcohol consumption, history of abortion, parity distance, and maternal BMI had no significant association (p>0.005).Conclusion: Thus, the incidence of LBW can be prevented through maternal blood control during the pregnancy. Careful history taking of past history of giving birth to LBW babies and the mode of delivery must be done to reduce the incidence of LBW. Pendahuluan: Kesehatan ibu dan anak merupakan salah satu fokus utama kesehatan di Indonesia. Kasus kematian ibu dan anak di Indonesia lebih tinggi dibandingkan dengan negara-negara di Asia Tenggara. Kejadian bayi berat lahir rendah (BBLR) berkontribusi terhadap lebih dari 50% total kematian neonatal di seluruh kelahiran di Indonesia. Oleh karena itu, identifikasi faktor-faktor risiko yang mendasari kejadian BBLR menjadi penting untuk dilakukan.Metode: Penelitian kasus kontrol retrospektif ini melibatkan 50 kasus (BBLR) dan 50 kontrol (bayi lahir dengan berat badan normal. Data yang diperoleh kemudian dianalisis menggunakan perangkat SPSS versi 22.Hasil: Hasil analisis multivariat didapatkan faktor-faktor yang memiliki hubungan signifikan dengan kejadian BBLR adalah tekanan darah ibu (p=0,000), riwayat melahirkan bayi BBLR (p=0,000), dan tipe persalinan bayi saat ini (p=0,034). Sebaliknya, faktor usia ibu, tingkat pendidikan ibu, pekerjaan ibu, anemia pada ibu, jumlah paritas, riwayat merokok, riwayat konsumsi alkohol, riwayat abortus, jarak paritas, dan IMT ibu tidak memiliki hubungan yang signifikan (p>0,005).Simpulan: Pencegahan kejadian BBLR dapat dilakukan dengan mengontrol tekanan darah ibu selama kehamilan. Penggalian riwayat melahirkan bayi BBLR sebelumnya dan pemilihan metode persalinan juga harus dilakukan dengan seksama untuk mengurangi kejadian BBLR.
Diagnosis dan tatalaksana rinosinusitis maksilaris odontogenik yang meluas sampai etmoid dan frontal: laporan kasus
Authors: Santosa Agus , Sari Nyoman Dian Permata , Putra Ida Bagus Semara , Masyeni Dewa Ayu Putu Sri 
Published: February 2022

Background: Sinusitis is an inflammatory process in the nasal mucosa, especially in the paranasal sinuses. Sinusitis problems are important and need special attention in cases of sinusitis that do not improve after being given conventional therapy. The purpose of this paper is to establish the diagnosis and management of odontogenic maxillary rhinosinusitis that extends to the ethmoid and frontal areas.Case presentation: A male patient, aged 22 years, came to the ENT clinic at Mangusada Hospital, Badung. Based on the history, physical examination, supporting examination in the form of CT-scan so that it was diagnosed as chronic rhinosinusitis et causa odontogenic which extends to the ethmoid and frontal. The treatment chosen was surgery in the form of Functional Endoscopic Sinus Surgery (FESS) and septorhinoplasty because in this case the patient had complications and did not respond to medical therapy. Postoperative evaluation, complaints of smelly mucus, nasal congestion and headache were not felt.Conclusion: The diagnosis of chronic rhinosinusitis et causa odontogenic which extends to the ethmoid and frontal based on CT-Scan and the treatment given to the patient in the form of FESS and septorhinoplasty. Latar belakang: Sinusitis merupakan proses inflamasi pada mukosa hidung, lebih khususnya pada sinus paranasal. Masalah sinusitis menjadi penting dan perlu perhatian khusus pada kasus sinusitis yang tidak membaik setelah diberikan terapi konvensional. Tujuan penulisan ini adalah untuk menegakkan diagnosis dan penatalaksan rinosinusitis maksilaris odontogenik yang meluas sampai etmoid dan frontal.Presentasi kasus: Seorang pasien laki-laki, berusia 22 tahun datang ke poli THT RS Mangusada, Badung. Berdasarkan anamnesis, pemeriksaan fisik, pemeriksaan penunjang berupa CT-scan sehingga didiagnosis sebagai rinosinusitis kronis et causa odontogenic yang meluas sampai etmoid dan frontal. Penatalaksanaan yang dipilih adalah pembedahan berupa Functional Endoscopic Sinus Surgery (FESS) dan septorhinoplasti, karena pada kasus ini pasien mengalami komplikasi dan tidak memberikan respon dengan terapi medikamentosa. Evaluasi pasca operasi, keluhan ingus berbau, hidung tersumbat dan nyeri kepala sudah tidak dirasakan.Kesimpulan: Diagnosis rinosinusitis kronis et causa odontogenic yang meluas sampai etmoid dan frontal berdasarkan dari CT-Scan dan tatalaksana yang diberikan pada pasien berupa FESS dan septorhinoplasti.
Interpretasi nilai Cycle Threshold (CT) Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) SARS-CoV-2 pada pasien hamil dengan uji antibodi SARS-CoV-2 positif dan COVID-19 asimtomatik
Authors: Candrawati Ni Wayan , Cassidy William Ray 
Published: February 2022

Background: The majority of pregnant women with COVID-19 will be asymptomatic throughout the disease period. SARS-CoV-2 antibody tests were utilized as a screening tool for patients giving birth in a hospital. Cycle Threshold (CT) value in asymptomatic pregnant women may guide patient management and isolation protocol.Methods: Research data were obtained from medical records from March until October 2020 with a total sampling method. Pregnant women with positive SARS-CoV-2 antibody and asymptomatic COVID-19 were included. CT-value based on gene primers were grouped and analyzed by Microsoft Excel 365 for Windows.Results: Twenty-five pregnant women with asymptomatic COVID-19 fulfilled the inclusion criteria. All patients had positive SARS-CoV-2 antibodies. The highest and lowest CT-value for the RdRp gene were 37.91 and 26.90, followed by N-gene (34.37 and 32.16), E-gene (38.36 and 27.60), helicase gene (35.65 and 24.29), ORF1a (35.87 and 26.80), and ORF1ab (41.28 and 27.82).Conclusion: SARS-CoV-2 antibody test is not a recommended screening tool as it can reveal past infection or immunity to SARS-CoV-2. CT-value is incapable of determining COVID-19 severity and infection period. Latar Belakang: Mayoritas pasien COVID-19 dengan kehamilan tidak bergejala sepanjang periode perjalanan penyakit. Uji antibodi SARS-CoV-2 sempat digunakan sebagai alat skrining pasien yang akan melahirkan di rumah sakit. Nilai Cycle Threshold (CT) pada pasien hamil dengan COVID-19 asimtomatik kemungkinan dapat memandu tatalaksana dan isolasi pasien.Metode: Penelitian ini menggunakan data sekunder rekam medis dari bulan Maret hingga Oktober 2020 dengan total sampling. Data pasien hamil dengan uji antibodi SARS-CoV-2 positif dan terkonfirmasi COVID-19 asimtomatik dianalisis. Nilai cycle threshold (CT-value) berdasar primer dikelompokkan dan dianalisis menggunakan Microsoft Excel 365 untuk Windows. Hasil: Sebanyak 25 pasien hamil dengan terkonfirmasi COVID-19 asimtomatik memenuhi kriteria inklusi. Seluruh pasien memiliki hasil tes cepat antibodi SARS-CoV-2 reaktif. Nilai CT tertinggi dan terendah untuk gen RdRp sebesar 37,91 dan 26,9, diikuti dengan gen N (34,37 dan 32,16), gen E (38,36 dan 27,60), gen helicase (35,65 dan 24,29), ORF1a (35,87 dan 26,80), dan ORF1ab (41,28 dan 27,82).Simpulan: Nilai CT tidak dapat digunakan sebagai indikator keparahan gejala dan periode infeksi COVID-19. Pasien hamil dengan COVID-19 asimtomatik tidak harus menjalani isolasi di rumah sakit.
Effect of prone positioning for improving oxygenation in awake non-intubated COVID-19 patient: a systematic review
Authors: Prabawa I Made Yoga , Silakarma Dedi , Susantio Sisca 
Published: February 2022

Background. The rapid rise of COVID-19 cases in many regions impacted on increasing needs of intensive care units and oxygen supplementation. The exponential COVID-19 infection with moderate to severe hypoxia that needs oxygen supplementation causes medical oxygen shortage in most hospitals and swamped the health care system. Prone positioning can be an alternate way for non-hospitalized COVID-19 patients, especially in the region facing oxygen and ward shortage in hospitals. This systematic review will describe the impact of the prone positioning method for improving oxygenation in awake non-intubated COVID-19 patients.Method. A systematic review using PubMed and Google Scholar was conducted based on PRISMA guidelines. We used inclusion criteria such as observational study with cross sectional, cohort, case-control or clinical trial study design regarding the effect of prone positioning for improving oxygenation in COVID-19 patients. Exclusion criteria were a letter to the editor, commentary reports, systematic review or meta-analysis, study involving non-awake and or intubated patients and study not available in full-text. Result. We gathered eleven studies consisting of six retrospective observational studies, three prospective observational studies and two clinical trials comprised of one randomized controlled trial and one interventional study. There are 791 awake non-intubated COVID-19 patients as the study sample. The measured outcomes are changes in SaO2, P/F ratio, S/F ratio, ROX index, intubation and mortality rate. The prone positioning duration varies between 29 minutes until 12 hours and helps improve oxygenation, reducing intubation and mortality. Conclusion. Prone positioning is feasible to apply in awake non-intubated COVID-19 patients. It can improve oxygenation, reduce intubation, mortality rate and be beneficial to overcome oxygen and mechanical intubation shortage during the COVID-19 pandemic.
Chemical constituents from the leaves of Styrax argentifolius H.L. Li and their antioxidative activity
Authors: Nguyen Thanh Tra , Pham Van Cuong , Nguyen Thi Thu Ha , Le Tu Anh , Ninh The Son 
Published: February 2022

Searching for bioactive agents from medicinal plants, the phytochemical investigation on the EtOAc extract of the Vietnamese Styrax argentifoliusÂ leaves has resulted in the isolation and structural determination of five compounds, including one nor-neolignan egonoic acid (1), one lignan (+)-pinoresinol (2), one sterol (20R)-3Î²-hydroxysitgmasta-5,22-dien-7-one (3), and two triterpenoids lupeol (4), and 2Î±,3Î±,24-trihydroxy-urs-12-en-28-oic acidÂ (5). The chemical structures of these secondary metabolites were elucidated by NMR and MS spectral data. All isolated compounds were first observed in S. argentifoliusÂ species. Sterol 3Â and triterpenoid 5Â were detected in genus StyraxÂ for the first time. With the IC50Â value of 19.10 Âµg/mL, compound 2Â possessed the strong activity in DPPH radical scavenging assay.