bluuebunny/crossref_metadata_2025_split huggingface dataset:
Non-communicable diseases in undocumented migrants: 10-year temporal trend, relative risk and pharmacological treatment
Authors: Fiorini Gianfrancesco , Franchi Matteo , Pellegrini Giacomo , Sartorio Alessandro , Corrao Giovanni , Cella Silvano Gabriele 
Published: October 2022

Abstract
Undocumented migrants are a large part of the population in the European Union (EU). Their health needs are only partially known and might be mainly related to chronic conditions. We studied the health records of 53.683 undocumented migrants receiving medical assistance over the last 10 years from a non-governmental organisation (NGO) in Milan, Italy. To identify NCD, we used the International Classification of Diseases – 9th revision (ICD-9) diagnostic codes and the Anatomical Therapeutic Chemical (ATC) codes of the prescribed drugs. Among persons having at least one contact with OSF in the period of the study, 17,292 had one or more NCD. The percentage of subjects with at least one NCD increased from 2011 to 2020. The risk of having NCD was higher in women than in men (RR = 0.87, 95% CI 0.85–0.89) and increased with age (p for trend < 0.001). Ethnicity affected the relative risk. Africans and Asians had a lower risk than Europeans of having cardiovascular diseases and mental disorders; risk was higher in Latin Americans. In migrants from Asia and Latin America the relative risk of diabetes was increased. In Europe, public interventions aiming at the prevention and treatment of NCD should include undocumented migrants.
Glycolipids from marine macroalgae: extraction methodology, isolation and biological activity
Authors: Sun Yingying , Long Zhengkang , Yi Lihui , Mu Yang , Huang Xinyan , He Yangdi 
Published: October 2022

Abstract
Considering the yield, concentration of glycolipids, moisture absorption and moisturizing activity of the extract, Bangia fusco-purpurea was selected from 8 species of marine macroalgae (Bangia fusco-purpurea, Gelidium amansii, Gloiopeltis furcata, Gracilaria lemaneiformis, Gracilaria sp., Palmaria palmata, Porphyra yezoensis and Scagassum sp.) as the raw material for the extraction methodology, isolation and purification of glycolipids. Through single factor and response surface experiments, the suitable extraction conditions (the solid-to-liquid ratio, extraction temperature, extraction time and ultrasonic power) of the glycolipids from Bangia fusco-purpurea was: 1:27 g/mL, 49 ℃, 98 min and 500 W. Using the optimized process, the yield of extract and concentration of glycolipids in extract obtained were 28.1% and 116.9 µg/mL. Further, three compounds (H12, H22 and H33) were obtained from Bangia fusco-purpurea by liquid-liquid extraction, silica gel column chromatography and preparation thin layer chromatography, namely hexadecanyl-1-O-α-D-arabinopyranosyloxy (1→4)-α-D-arabinopyranosyloxy (1→4)-α-D-arabinopyranoside, β-Gal-(1–3)-β-Xyl, and docosanyl-1-O-α-D-arabinopyranosyloxy-(1→4)-3-O-acetyl -α-D-arabinopyranosyloxy-(1→4)-α-D-arabinopyranoside. This is the first report that these three compounds were isolated from Bangia fusco-purpurea. And those two with arabinopyranosyloxy (H12 and H33) were obtained from marine macroalgae for the first time. Also, the glycolipids from Gelidium amansii, Gloiopeltis furcata, Gracilaria lemaneiformis, Gracilaria sp., Palmaria palmata, Porphyra yezoensis and Scagassum sp. were preliminarily determined by TLC and HPLC, and compared with glycolipid standard (MGDG, SQDG, DGDG), and found that MGDG or SQDG was existed in 7 species of marine macroalgae.
Qualitative description of outreach and engagement in perinatal substance treatment in Finland
Authors: Sorsa Minna , Hohenthal Maria , Pikulinsky Miia , Sellergren Hanna , Puura Kaija 
Published: October 2022

Abstract
Background
Women with perinatal substance problems experience barriers to care if they do not disclose their health problems. They have specific early intervention needs, they endure societal stigma, and both substances and mental health issues influence the manner how they navigate within support and treatment systems. Early interventions for women with perinatal substance problems are under-researched contexts.
Methods
We studied an early intervention program designed and aimed at reaching out to pregnant women and mothers with small children, which includes outreach and low threshold elements. The data consist of online written narratives from 11 workers involved in the program and feedback from 504 families in the recovery process comprised of 228 open-ended answers. The data were analyzed with a thematic analysis.
Results
The programs are characterized by flexibility and the implementation of new methods to approach families. The themes for enhancing relationships and engagement within outreach and low threshold programs are: Acceptance and attitude: a sensitive approach of approval; flexibility within strictness to allow for diversity and individuality; availability and space to ensure calmness in a trustful atmosphere; negotiating via doing to build connections; and everyday life changes: imagining recovery.
Conclusions
To enhance building connections between workers and women in need of intervention, the entire family situation needs to be acknowledged. Fathers’ or partners’ continuing substance abuse and women’s weak status in a world of substance abuse may make it difficult for women to enter and engage in treatment. One suggestion is to ensure long-term SUD treatment can be initiated during pregnancy. Many families will profit from outreach and low threshold services, so that they will not need to even enter long-standing recovery programs. By informing and messaging about substance-abuse services, for example on social media and other platforms, knowledge about such services will reach those in need. In addition, providing professionals with anti-stigma training and the general public with information about services and SUD treatment may mitigate the stigma related to substance-abuse treatment.
DNA methylation is involved in sex determination in spinach
Authors: Jia Keli , Duan Jiaming , Cheng Guangqian , Li Heng , Li Shufen , Hu Miao 
Published: October 2022

Abstract
To explore whether DNA methylation plays different roles in the spinach development of individual male and female dioecious plants, methylation sensitivity amplification polymorphism (MSAP) was used to assess differential cytosine CpG methylation profiles of CCGG motifs of the spinach. 16 pairs of amplification primers were selected, A total of 434 DNA fragments, of which 134 methylated fragments were detected in the male and female plants. The relative ratios of the methylated sites did have sex-specific differences, which was 28.8% and 33% in the male and female. In addition, 32 sex-specific cytosine methylation bands were obtained, 15 fragments were male specific and 17 fragments were female specific. The level of cytosine methylation on CCGG was higher in female genomes than male genomes. The methylation level of CG island was involved in the sex determination and the differentiation process of spinach, which provided information for revealing the sex determination of spinach.
Triangulations of Grassmannians and flag manifolds
Authors: Abawonse Olakunle S 
Published: October 2022

Abstract
MacPherson in\cite{macp:rob} conjectured that the Grassmannian \(\mathrm{Gr}(2, \mathbb{R}^n)\) has the same homeomorphism type as the combinatorial Grassmannian \(\mbox{MacP}(2,n)\) , while Babson\cite{bab:eric} proved that the spaces \(\mbox{Gr}(2,\mathbb{R}^n)\) and \(\mbox{Gr}(1,2,\mathbb{R}^n)\) are homotopy equivalent to their combinatorial analogs, the simplicial complexes \(\|\mbox{MacP}(2,n)\|\) and \(\|\mbox{MacP}(1,2,n)\|\) respectively. We will prove that \(\mbox{Gr}(2, \mathbb{R}^n)\) and \(\mbox{Gr}(1,2, \mathbb{R}^n)\) are homeomorphic to $\|\mbox{MacP}(2,n)\|$ and $\|\mbox{MacP}(1,2,n)\|$ respectively
Spatial and temporal variation of floral visitors and their visitation pattern on Acanthus ilicifolius L.: A case study from the Indian Sundarbans
Authors: CHATTERJEE TANIA , Chakrabarty Souparna , Roy Sankarsan , Biswas Olive , Mitra Bulganin , Chaudhuri Punarbasu 
Published: October 2022

Abstract
Acanthus ilicifolius is a spiny semi-woody evergreen shrub which is one of the most dominant mangrove associate species. Although its floral biology is well documented, there is not enough systematic study of floral visitors of this species. Successful plant reproduction is highly dependent on plant-pollinator interaction. The present study aims to understand the range of floral visitors of A. ilicifolius and their spatio-temporal variation in visitation pattern from the Indian Sundarbans. This study was conducted in five islands of Sundarbans Biosphere Reserve (SBR), namely, Bali, Gosaba, Satjelia, Gangasagar and Bakkhali during 2015 and 2016. Fifteen flower visitors under five taxonomic orders, i.e., Hymenoptera, Coleoptera, Diptera, Lepidoptera and Passeriformes were identified. Seven out of these fifteen species were reported for the first time as floral visitor of A. ilicifolius. Order Hymenoptera was the most frequent insect group, whereas Apis mellifera of this order was the predominant flower visitor. Although Gangasagar and Bakkhali being tourist spots, face greater anthropogenic interference, they had the highest abundance of floral visitors. A significant variation in floral visitor abundance was observed across different time of the day throughout the study period. Floral visitors were most abundant in the morning between 8 a.m. to 12 p.m. This study provides the first comprehensive report of diversity and abundance of the floral visitors and their visitation pattern on A. ilicifolius. Implications for insect conservation: Proper documentation of the ecology of insect pollinators would automatically help to conserve the plants along with the insects, and thus preserve the entire mangrove ecosystem of the Sundarbans as well as mangroves around the world.
Detrimental Consequences after Intimal Disruption of Subclavian Artery during Transcathether Aortic Valve Implantation
Authors: Reuthebuch Oliver T. , Vasiloi Ion , Nestelberger Thomas , Wolff Thomas , Eckstein Friedrich 
Published: October 2022

Abstract
Background: TAVI via the left subclavian artery is considered a bail-out strategy in cases where a transfemoral approach is not feasible. However, since this route is only scarcely used, major complications can arise. We describe such an adverse course and present our proceeding.
Case presentation:A 65-year-old man with severe aortic valve stenosis (AS) was referred for transcatheter aortic valve implantation (TAVI) via left subclavian artery. After uneventful deployment of the TAVI prosthesis, consequent valve assessment with transeosophageal echocardiography and angiography showed a highly mobile and tubular structure shifting within the valve. We went for a surgical extraction via sternotomy on cardiopulmonary bypass (CPB). A 6cm longish intimal cylinder was hassle-free extracted. 4 days postoperatively the left sided radial pulse was missing. In a subsequent computed tomography angiography (CTA) scan a proximal dissection as well as an intimal flap, causing a subtotal stenosis of the left subclavian artery, was detected. Consecutively the intimal cylinder was removed using a Fogarty-balloon. Pre-discharge control revealed recurrence of peripheral radial pulse and an unimpeded function of the TAVI prosthesis. The patient presented no sequela at discharge.
Conclusion: Though TAVI is a well-advanced technique complications are not completely avertable. Therefore, it is advisable to have recourse to cardiac surgery.
Study of the Relationship between Malignant Pleural Effusion and
Common Causing Tumors
Authors: Juha Kinda , Al-bardan Hossam 
Published: October 2022

Abstract
Introduction:
Malignant pleural effusion is one of the most important causes of pleural effusion. It can sometimes be difficult to diagnose a malignant effusion due to the uncertainties of biopsy determination of a pleural result. The aim of this study was to evaluate the clinical features of malignant pleural effusion.
Methods:
A retrospective study on patients with malignant pleural effusion at Al-Mujtahid Hospital and Ibn Al-Nafis from December 2021 to June 2022.
Results:
Of the 188 patients, admitted with a story, 40.4% were adult patients, adults, adults, adults, and girls. The mean age of the patients was 56 years. Mount infected by 51.1%. And 12.8% had the right-sided patients with 57.4%, and the left-sided patients had the disease. Tumor effusions were treated 63%, pleurisy 13%, and chest blasting 24.1%. Effusion analysis of 91.5% exudate pattern, 8.5% transudate pattern, presence of malignant cells at 10.6%. The demographic dialogue of patients and adjacent factors was associated with both effusion and primary tumor. (P < 0.05).
Conclusion:
The results of this study indicate that there are issues related to pleural effusion. Programs should aim at using modern methods of diagnosing and treating malignant pleural effusion as it has an important role in determining the prognosis.
Performance assessment of the operational management of urban drainage systems: a case study of Bejaia City, Algeria
Authors: Igroufa Meriem , Benzerra Abbas , Seghir Abdelghani , Merah Ferhat , Bedjou Abdelhamid 
Published: October 2022

Abstract
Over the recent years, managers of the Algerian National Sanitation Office (ONA) have been worrying about the degraded state of their Urban Drainage Systems (UDS). This infrastructure failure is due essentially to the lack of funding and absence of adequate structured methodology for diagnosis and maintenance. As a result, ONA's managers found it very interesting to get a tool that allows them to assess their management of UDS operation. The aim of this paper is therefore to provide an assessment tool to managers for a good network operation. The adopted approach is participative and takes into account the specific local context. Six performance indicators, grouped into two criteria, have been constructed to achieve this objective. These indicators have been chosen for their effectiveness; they are scaled to get their performance scores according to a scaling constructed here based on standards when available and to the ONA expert's recommendations. The developed tool is applied to the UDS of Bejaia City, in north-eastern Algeria. The assessment and the analysis of the performance evolution of these indicators for the period 2017–2021 are carried out. The results highlighted successes that can be maintained as well as weaknesses that need to be improved.
The modification of biomass waste by cerium-based MOFs for efficient phosphate removal: excellent performance and reaction mechanism
Authors: He Jiaojie , Yang Yixing , Qu Min , Yang Yue , Yang Liwei 
Published: October 2022

Abstract
Due to the possibility of causing eutrophication, excessive phosphate discharged into water bodies always threatens the stabilization of aquatic ecosystem. A promising strategy is to remove phosphate from water by the utilization of biomass waste as adsorbents. In this paper, the corn straw (CS) and pine sawdust (PS) are chosen for adsorption; however, the phosphate removal capacities of them are very limited. Considering the high phosphate uptake of trivalent cerium, Ce (III)-based nanoparticles (CD and CT) are selected to be loaded on the biomass by hydrothermal synthesis to obtain four modified materials. CD is metal organic frameworks (MOFs) with Ce5(BDC)7.5(DMF)4 as its molecular structure, while CT is MOFs derivatives with [Ce (HCOO)]n as its crystal structure. The adsorption capacities of CS-CD, PS-CD, CS-CT and PS-CT reach 181.38, 183.27, 225.55 and 186.23 mg/g. But on account of the different molecular structures, CS-CD and PS-CD achieve great phosphate uptake under wide applicable scope of pH from 2 to 11, whereas CS-CT and PS-CT only under acidic conditions. The analysis of the adsorption mechanism indicates that due to the unsaturated coordination bond of CD, it could remove phosphate through coprecipitation and ion exchange even under alkaline conditions.
Stereoscopic Differences in the Identification, Bioactivity, and Metabolism
of C-20 and C-24 Epimeric Ginseng Saponins
Authors: Zhang Juan , Zhao Ruolin , Hou Guige , Wang Qibao , Zhao Fenglan , Liu Zhi , Meng Qingguo 
Published: October 2022

Abstract:
Ginseng, the roots and/or rhizomes of Panax spp.(Araliaceae), has been used as a popular, herbal medicine in East Asia for at least two millennia. As a functional food and health-enhancing supplement, ginseng has been shown to have a wide range of pharmacological effects on cognition and blood circulation as well as antioxidant, antitumor, and anti-fatigue effects. The main active properties of ginseng are considered to be the triterpene saponins, often referred to as ginsenosides, which are the basis for their wide-ranging of pharmacological effects. Four of these glycosides, including protopanaxadiol, protopanaxatriol, ocotillol, and oleanolic acid, are the most common saponins found in ginseng. Compared to other ginsenosides, the C-20 chimeric ginsenosides, including Rg3, Rh2, Rg2, Rh1, PF11, C-20, and C-24, as well as epimeric ocotillol-type saponins and their derivatives exhibit significant, steric differences in biological activity and metabolism. 20(R)-ginseng saponins, one class of important rare ginsenosides, have antitumor, antioxidative, antifatigue, neuroprotective and osteoclastogenesis inhibitory effects. However, 20(R)-ginsenosides are rare in natural products and are usually prepared from 20(S)-isomers through chemical differential isomerization and microbial transformation. The C20 configuration of 20(R)-ginseng saponins is usually determined by 13C NMR and X-ray single-crystal diffraction. There are regular differences in the chemical shift values of some of the carbons of the 20(S)- and 20(R)-epimers, including C-17, C-21, and C-22. Owing to their chemical structure and pharmacological and stereoselective properties, 20(R)-ginseng saponins have attracted a great deal of attention in recent years. Herein, the stereoscopic differences in the identification, bioactivity, and metabolism of C-20 and C-24 epimeric ginseng saponins are summarized.
Stem Cell and Oxidative Stress-Inflammation Cycle
Authors: Buzoglu Hatice Dogan , Burus Ayse , Bayazıt Yasemin , Goldberg Michel 
Published: October 2022

:
Under a variety of physical and experimental settings, stem cells are able to self-renew and
differentiate into specialized adult cells. MSCs (mesenchymal stromal/stem cells) are multipotent stem
cells present in a wide range of fetal, embryonic, and adult tissues. They are the progenitors of a variety of
specialized cells and are considered crucial tools in tissue engineering. MSCs, derived from various tissues,
including cord blood, placenta, bone marrow, and dental tissues, have been extensively examined in
tissue repair, immune modulation, etc. Increasing the vitality of MSCs and restoring cellular mechanisms
are important factors in treatment success.

:
Oxidative stress harms cellular molecules such as DNA, proteins, and lipids due to the overproduction of
reactive oxygen species (ROS) and reactive nitrogen species (RNS) in cells and tissues or insufficiency of
antioxidant systems that can inactivate them. Oxidative stress has a close link with inflammation as a
pathophysiological process. ROS can mediate the expression of proinflammatory genes via intracellular
signaling pathways and initiate the chronic inflammatory state. At the same time, inflammatory cells secrete
a large number of reactive species that cause increased oxidative stress at sites of inflammation. In
inflammatory diseases, the differentiation of stem cells and the regenerative and wound healing process
can be affected differently by the increase of oxidative stress.

:
Recent studies have indicated that dental pulp stem cells (DPSCs), as a resource of adult stem cells, are an
attractive option for cell therapy in diseases such as neurological diseases, diabetes, cardiological diseases,
etc., as well as its treatment potential in pulp inflammation. The future of oxidative stressinflammation
cycle and/or ageing therapies involves the selective elimination of senescent cells, also
known as senolysis, which prevents various age-related diseases. Most pathologies are implicated on the
effects of ageing without exerting undesirable side effects.
The Growth-promoting and Antipathogenic Effects of Microorganisms Isolated from Solanum nigrum L. and Inoculated in Solanum lycopersicum L.
Authors: Borodai Vira V. , Kolomiiets Yuliia V. , Likhanov Artur F. , Zelena Liubov B. , Butsenko Lyudmyla M. , Shemetun Kateryna I. , Churilov Andrii M. , Blume Yaroslav B. 
Published: October 2022

Background:In recent years, there has been a growing scientific interest in the biodiversity and function of endophytic bacteria, as well as the prospects for their practical use.Objective:The purpose of this work was to isolate endophytic microorganisms from generative organs of the European black nightshade (Solanum nigrumL.), assess their biological activity, and test their growth-promoting/protective effects in tomato (Solanum lycopersicumL.) plants.Methods:From the tissues of generative organs ofS. nigrumplants, 14 strains of endophytic microorganisms were isolated. Most of them belonged toBacillussp. The physiological and biochemical properties and enzymatic and oxidative metabolism of some of them were studied. Sequence analysis of 16S rRNA fragments revealed 99,65% similarity of BA1s-OSN-0820 and BAXS-OSN-0820 isolates toB. amyloliquefaciensstrains, while the ITS sequence of the RHC-OSN-0820 isolate showed 99,65% of similarity toRhodotorula kratochvilovae.Results:The actions of these endophytes against tomato pathogenic bacteria and fungi were then tested. The isolates had a significant bacteriostatic effect againstXanthomonas campestris,the causative agent of black bacterial spotting of leaf, andClavibacter michiganensis,the causative agent of bacterial wilt, with a lower effect againstPseudomonas syringae,the causative agent of bacterial spotting. Isolates also showed selectivity against micromycetes that cause mycosis in tomatoes grown indoors, such asFusarium oxysporum, Alternaria solani, Botrytis cinerea, Sclerotinia sclerotiorum,andF. acuminatum. In particular, the highest antifungal activity was detected againstS. sclerotiorumand fungi of theFusariumgenus. Inoculation of tomatoes with endophytic microorganisms revealed a positive effect on seed germination efficiency and the stimulation of seedling growth. Thus, the effectiveness of interspecific transfer of endophytic microorganisms from a wild,S. nigrum,to a cultivatedSolanumspecies,S. lycopersicum,was reported.Conclusion:A consortium of plant-associated microorganisms isolated from a wild relative has a positive effect on the germination of tomato seeds, stimulating the formation of the root system and nutrition of seedlings. The antagonism of the isolates against phytopathogenic fungi and bacteria provides long-term protection during the most critical stages of plant development and has prospects for the development of microbial biologics for cultivated plants of the Solanaceae family.
Pectin/Pectin Derivatives as Potential Scaffolds for the Tissue Engineering
Applications
Authors: Pandey Akanksha , Sharma Pramod Kumar , Malviya Rishabha , Rahate Kalpana 
Published: October 2022

Abstract:
Pectins are polysaccharides that have a sequence that is similar to that of plant cell membranes
that are predominantly made up of galacturonic acid units, and their concentration, morphology,
and molecular mass vary. Tissue engineering is a multidisciplinary field that examines natural
replacement for the injured tissue to heal or preserve its function, and it involves using scaffolds, cells,
and biomolecules. Biocompatible, biodegradable, and permeable scaffolds are required. The study
aims to find the potential of pectin/pectin derivative scaffolds for tissue engineering applications.