bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of the Intraoperative Blood Loss and Intraoperative Blood Transfusion on the Short-Term Outcomes and Prognosis of Colorectal Cancer: A Propensity Score Matching Analysis
Authors: Kang Bing , Liu Xiao-Yu , Li Zi-Wei , Yuan Chao , Zhang Bin , Wei Zheng-Qiang , Peng Dong 
Published: April 2022

PurposeThe purpose of the current study was to analyze the effect of intraoperative blood loss (IBL) and intraoperative blood transfusion (IBT) on the short-term outcomes and prognosis for patients who underwent primary colorectal cancer (CRC) surgery.MethodsWe retrospectively collected the patients' information from the database of a teaching hospital from January 2011 to January 2020. IBL and IBT were collected and analyzed, and the propensity score matching (PSM) analysis was performed.ResultsA total of 4,250 patients with CRC were included in this study. There were 1,911 patients in the larger IBL group and 2,339 patients in the smaller IBL group. As for IBT, there were 82 patients in the IBT group and 4,168 patients in the non-IBT group. After 1:1 ratio PSM, there were 82 patients in the IBT group and 82 patients in the non-IBT group. The larger IBL group had longer operation time (p = 0.000 &lt; 0.01), longer post-operative hospital stay (p = 0.000 &lt; 0.01), smaller retrieved lymph nodes (p = 0.000 &lt; 0.01), and higher overall complication (p = 0.000 &lt; 0.01) than the smaller IBL group. The IBT group had longer operation time (p = 0.000 &lt; 0.01), longer hospital stay (p = 0.016 &lt; 0.05), and higher overall complications (p = 0.013 &lt; 0.05) compared with the non-IBT group in terms of short-term outcomes. Larger IBL (p = 0.000, HR = 1.352, 95% CI = 1.142–1.601) and IBT (p = 0.044, HR = 1.487, 95% CI = 1.011–2.188) were independent predictive factors of overall survival (OS). Larger IBL (p = 0.000, HR = 1.338, 95% CI = 1.150–1.558) was an independent predictor of disease-free survival (DFS); however, IBT (p = 0.179, HR = 1.300, 95% CI = 0.886–1.908) was not an independent predictor of DFS.ConclusionBased on the short-term outcomes and prognosis of IBL and IBT, surgeons should be cautious during the operation and more careful and proficient surgical skills are required for surgeons.
Heat Transfer of Hybrid Nanomaterials Base Maxwell Micropolar Fluid Flow over an Exponentially Stretching Surface
Authors: Li Piyu , Z. Duraihem Faisal , Awan Aziz Ullah , Al-Zubaidi A. , Abbas Nadeem , Ahmad Daud 
Published: April 2022

A numerical investigation of three-dimensional hybrid nanomaterial micropolar fluid flow across an exponentially stretched sheet is performed. Recognized similarity transformations are adopted to convert governing equations from PDEs into the set ODEs. The dimensionless system is settled by the operating numerical approach bvp4c. The impacts of the nanoparticle volume fraction, dimensionless viscosity ratio, stretching ratio parameter, and dimensionless constant on fluid velocity, micropolar angular velocity, fluid temperature, and skin friction coefficient in both x-direction and y-direction are inspected. Graphical outcomes are shown to predict the features of the concerned parameters into the current problem. These results are vital in the future in the branches of technology and industry. The micropolar function Rη increases for higher values of the micropolar parameter and nanoparticle concentration. Micropolar function Rη declines for higher values of the micropolar parameter and nanoparticle concentration. Temperature function is enhanced for higher values of solid nanoparticle concentration. Temperature function declines for higher values of the micropolar parameter. The range of the physical parameters are presented as: 0.005<ϕ2<0.09, Pr=6.2, 0<K<2, 0<a<2.0, ϕ1=0.1, and 0<c<1.5.
Identifikasi Waste Menggunakan Waste Assessment Model (WAM) di Warehouse Raw Material PT. XYZ
Authors: Naziihah Afifah , Arifin Jauhari , Nugraha Billy 
Published: April 2022

Warehouse of Raw Materials in PT. XYZ show an increase in the storage of the good, if is not offset by good performance, then the goods will be experiencing delays in handling. This study aims to identify the waste that occurs in the Warehouse of Raw Materials in PT. XYZ. The focus of this research is to identify the 7 wastes in the Warehouse raw materials with the lean manufacturing approach using the method of Waste Assessment Model (WAM). The process of waste identification is performed by using Seven Waste Relationship, Waste Relationship Matrix (WRM) and Waste Assessment Questionnaire (WAQ) later in the analysis using a Fishbone Diagram to determine the root cause of the problem so we get the proposal improves then the priority of the improvement obtained by using the table of priorities that is done by way of brainstorming. The study was conducted for 1 month starting March 24-April 23, 2021. The results showed the ranking of waste ranging from the largest to the smallest Defect of 22.70%, Overproduction of 18.32%, Inventory of 17.56%, Motion by 14.12%, Transportation of 13.10%, Waiting by 9.68% and the Process by 4.52%. The results of the waste with the largest percentage is Defect.Warehouse Raw Material di PT. XYZ menunjukkan peningkatan pada penyimpanan barang, jika tidak diimbangi dengan kinerja yang baik, maka barang yang masuk akan mengalami keterlambatan dalam penanganan. Penelitian ini bertujuan untuk mengidentifikasi pemborosan yang terjadi di Warehouse Raw Material di PT. XYZ. Fokus kajian penelitian ini adalah mengidentifikasi 7 waste yang ada di Warehouse Raw Material dengan pendekatan lean manufacturing menggunakan metode Waste Assessment Model (WAM). Proses identifikasi waste dilakukan dengan menggunakan Seven Waste Relationship, Waste Relationship Matrix (WRM) dan Waste Assessment Questionnaire (WAQ) yang kemudian di analisis menggunakan Fishbone Diagram untuk mengetahui akar penyebab masalah sehingga didapatkan usulan perbaikan yang kemudian prioritas perbaikan didapat dengan menggunkan tabel skala prioritas yang dilakukan dengan cara brainstorming. Penelitian dilakukan selama 1 bulan mulai tanggal 24 Maret-23 April 2021. Hasil penelitian menunjukkan peringkat waste mulai dari terbesar sampai terkecil yaitu Defect sebesar 22.70%, Overproduction sebesar 18.32%, Inventory sebesar 17.56%, Motion sebesar 14.12%, Transportation sebesar 13.10%, Waiting sebesar 9.68% dan Process sebesar 4.52%. Hasil waste dengan persentase terbesar adalah Defect.
Silvia Ortiz Echaniz (1940-2021), antropóloga de la religiosidad popular mexicana
Authors: Garma Navarro Carlos 
Published: April 2022

La antropóloga Silvia Ortiz Echaniz falleció en la ciudad de México el 27 de junio de 2021. Fue pionera en la investigación de la religiosidad popular en México, siendo una de las primeras mujeres latinoamericanas en dedicarse a su estudio desde una etnografía rigurosa y detallada, mediante prolongadas estancias de campo. Destacó por sus estudios sobre el Espiritualismo Trinitario Mariano, agrupación religiosa a la que le dedicó la mayor parte de su obra antropológica. Su primera profesión fue como maestra normalista. Más tarde estudió en la Escuela Nacional de Antropología e Historia, donde se tituló en 1968 con una tesis sobre la cultura popular, los procesos de trabajo y la movilidad ocupacional en San Andrés Cholula, Puebla. Dicha tesis formó parte de una investigación mayor dirigida por Guillermo Bonfil, dada a conocer en 1973 con el título Cholula, la ciudad sagrada en la era industrial, publicada por Universidad Nacional Autónoma de México (UNAM)
BRASIL E PARAGUAI FRENTE À PANDEMIA DO COVID-19
Authors: MOTA THAYNAH SANTANA , DE SOUZA RODRIGO NASCIMENTO HENKING , LESSA PABLO HENRIQUE CORDEIRO 
Published: April 2022

O presente trabalho aborda o contraste entre as medidas sanitárias de enfrentamento à pandemia do Coronavírus adotadas pelos governos federais do Brasil e Paraguai, dois Estados Partes do MERCOSUL cujos sistemas de saúde são notórios por suas deficiências, mas cujos cômputos de casos de COVID-19 e mortes em sua decorrência afiguram-se de maneira drasticamente antagônica. Tenciona deslindar, sob o prisma do Direito Sanitário, as atuações governamentais emergenciais ocasionadoras da discrepância entre os cenários de espraiamento do novo vírus em ambos os países, bem como aludir, sob a perspectiva do Direito de Integração, os benefícios e/ou malefícios advindos da ausência de cooperação entre membros de um mesmo bloco econômico. Para tanto, realiza breve contextualização do Direito Sanitário em ambas as nações, e compara as medidas de combate ao Coronavírus por elas aplicadas. Utiliza como metodologia pesquisa bibliográfica, consulta a websites governamentais e conteúdo midiático. Conclui que o Paraguai priorizou medidas copiosamente preventivas em detrimento de sujeitar-se ao precário sistema de saúde nacional para remediação, tendo sido a primeira nação sul-americana a executar providências quando a pandemia ainda se atinha aos outros países; o Brasil, em seu turno, preteriu diligências profiláticas ao executá-las apenas quando atingiu um quantum considerável de casos, resultando na sobrecarga do seu já exaurido e deficiente sistema de saúde. Inferiu, ainda, que a busca pela integração, mesmo que mínima, entre os Estados Partes do MERCOSUL durante momento histórico tão sui generis, teria beneficiado as nações e concorrido pela garantia do maior bem jurídico de seus povos: a vida.
Palavras-chave: Direito sanitário. Direito de integração. MERCOSUL. Estado de emergência. COVID-19.
PESSOAS REFUGIADAS NO BRASIL
Authors: ALMEIDA ARISLENE DA SILVA , SEREJO JORGE ALBERTO MENDES 
Published: April 2022

Frente a uma das maiores migrações da recente história da América Latina, o refúgio enquanto instituto no âmbito do Direito Internacional disciplinado pela Convenção relativa ao Estatuto dos Refugiados de 1951 e seu Protocolo de 1967, ambos ratificados pelo Brasil, anseia por especial atenção em momentos de acirramento das vulnerabilidades ensejadoras do seu pedido. O Estado brasileiro enfrenta há anos consideráveis problemas em virtude do excessivo número de solicitações de refúgio, especialmente no ano de 2018, quando o país reconheceu um total de 1.086 refugiados de diversas nacionalidades, em sua maioria de venezuelanos. Em 2020, o mundo foi assolado pela pandemia, em verdade uma sindemia causada pelo Coronavírus (SARS-Cov-2), algo que vem afetando em maior ou menor medida as respostas dos países sobre questões centrais no campo dos direitos humanos, como é a questão do refúgio. Neste contexto, a partir de levantamento bibliográfico e documental sobre o tema, a presente pesquisa exploratória investiga como se deu o tratamento da situação do refúgio no Brasil, seja no que diz respeito à solicitação e eventual aprovação pelo CONARE (Comitê Nacional para os Refugiados), seja nas políticas públicas que o Estado tem destinado aos refugiados, nos primeiros meses da pandemia no Brasil.

Palavras-chave: Refúgio. Direito Humanos. Pandemia.
Signal-Flow-Graph Analysis of Weakly Nonlinear Microwave Circuits around a Large-Signal Operating Point
Authors: Amakawa Shuhei , Sugimoto Ryotaro , Tokgoz Korkut Kaan , Lee Sangyeop , Ito Hiroyuki , Kishikawa Ryoko 
Published: April 2022

<p>Signal flow graph (SFG) representation of small-signal responses of nonlinear microwave circuits around a large-signal operating point is developed using the X-parameters. It is shown that, unlike the SFGs for linear circuits, negative-frequency nodes need to be included explicitly. The development elucidates the circuit-operational meaning of the elusive T-type small-signal X-parameters, which represent interaction between positive- and negative-frequency components. As an example, such an SFG is used to derive a closed-form expression of the output power of an amplifier as a function of the load reflection coefficient. It is then used to plot approximate load-pull power contours. The result is consistent with the expressions of the optimum load reflection coefficient derived by Root et al. (EuMIC 2017) and of power contours derived by Peláez-Pérez et al. (TMTT 2013). SFGs provide an alternative systematic means to derive closed-form expressions in terms of X-parameters and to gain illuminating insights into the workings of weakly nonlinear circuits. </p>
The Publishing Race
Authors: Misbach A.W. 
Published: April 2022

In October 2020, The Thinker received an open letter from Waghied Misbach as part of a call for papers on a special edition on “Race. Racism. Anti-Racism.” As this letter was about what he termed, “the erasure of black lives” in publishing, I decided to publish the letter and invited Terry Morris from Pan Macmillan to respond in the interests of fairness and open debate.
Terry Morris, in turn, sent the letter to Fiona Snyckers. While Fiona Snyckers send me a response, it was not addressed as an open letter. As such, it has not been published here. What follows is the original open letter from Waghied Misbach, Terry Morris’ response and finally Waghied Misbach’s response in return. Due to publication deadlines for this issue, we have not been able to follow up on this debate any further at this time. The Thinker supports open debate and academic freedom. However, a portion of the first letter has been redacted with the author’s permission, due to the potential for litigation. The Thinker encourages a scholarly engagement of ideas and does not serve as a vehicle for potentially litigious comment.
Casting the George Floyd story in a broader context
Authors: Tjihenuna Gerson Uaripi 
Published: April 2022

On 9 June 2020, viewers around the globe were glued to international TV networks to watch the live coverage of the funeral of George Floyd, an African-American man who was killed by the police during an arrest in Minneapolis on May 25 2020. Police brutality against African-Americans is not something new and this is what led to the slogan ‘Black Lives Matter’ that has been the lodestar of the recent waves of protest. The American Police Force is embedded with systemic racism which seems to have been reinforced by Donald Trump’s presidency.
However, the brutal killing of Floyd should be understood in a broader context. The Black race has gone through many dehumanising experiences, including the Trans-Atlantic slave trade, colonialism, and all manner of discrimination. This, in turn, has led to an inferiority complex because, for the most part, we have been defined by others – and not in the most positive of terms to say the least. There is a need for a conscious paradigm shift to transcend from a negative self-image to a positive one on the part of Black people all over the world. It is high time we stood up to define ourselves.
PASAR WISATA TANAMAN HIAS DI KARANGANYAR DENGAN PEMECAHAN MASALAH REKREATIF DAN PROMOTIF
Authors: Respati Agung , Ismadi  , Rully  
Published: April 2022

Karanganyar mempunyai kondisi geografis yang sangat baik untuk budidaya tanaman hias. Banyak petani berprofesi sebagai pengusaha tanaman hias, namun manajemen pemasarannya masih tradisional, yakni mengandalkan orang yang kebetulan datang ke kebun tanamannya. Hal ini menjadikan penghasilan mereka minim. Permasalahannya adalah fasilitas apa yang harus disediakan agar dapat meningkatkan omzet penjualan para pengusaha tanaman hias ini? Adapun tujuan penelitian adalah untuk mendapatkan konsep perencanaan dan perancangan arsitektur yang tepat. Metode yang digunakan dalam penelitian ini ialah deskriptif, analitik, dan sintetis. Hasil penelitian didapatkan sebuah desain pusat pasar wisata tanaman hias yang berkonsep rekreatif dan promotif di daerah Tawangmangu, kabupaten Karanganyar.
Kata kunci: Pasar Wisata,Rekreatif, Promotif
Effectiveness of trans-scleral cyclophotocoagulation for refractory paediatric glaucoma
Authors: Azhar Fiza , Qayyum Sema , Mushtaq Asma , Raza Ahmed , Zaman Asad 
Published: April 2022

Background: The aim of this study was to find out the effectiveness of trans-scleral cyclophotocoagulation in lowering intraocular pressure in the paediatric population.Patients and methods: This quasi-experimental study was conducted between July 2020 and January 2021 in Department of Ophthalmology, The Children’s Hospital, Lahore. Total 45 eyes of 42 children of age 1-14 years, both genders, with glaucoma were enrolled in this study. Diode cyclophotocoagulation unit and probe of make Quantel Medical was used for cycloablation under general anesthesia. Postoperative intraocular pressure was noted by using handheld Perkins applanation tonometer Mk2 after every 3 weeks for 12 weeks. If an IOP of ≤21mmHg was achieved, then efficacy or success was labeled. Patients with an IOP of >21mmHg after 12 weeks were selected for repeat cycloablation treatment. Failure was labeled to an IOP of >21mmHg even after a repeat session. Data analysis was done using SPSS 24. Results: In this study, 45 eyes were included with a mean age of 4.49 ± 3.12 years. There were 21 (46.7%) males and 24 (53.3%) females. At the time of presentation, the most common diagnosis was primary congenital glaucoma [28 (62.2%)], followed by aphakic glaucoma [10 (22%)], Anterior segment dysgenesis [2 (4.4%)], Pseudophakic glaucoma [2 (4.4%)], Sturge weber syndrome [2 (4.4%)] and Post-traumatic [1 (2.2%)]. The mean IOP at baseline was 26.67±3.66 mmHg, which was reduced to 19.60±6.33 mmHg with mean change in IOP of 7.07±4.56 mmHg (p<0.05). The mean anti-glaucoma drugs used at baseline was 2.91±0.42, which was reduced to 0.93±1.2 with mean change in use of anti-glaucoma drugs of 1.98±1.06 (p<0.05). Success was achieved in 34 (75.56%) eyes, while 11 (24.44%) needed second session. After repeat session 2 (4.4%) eyes went into treatment failure.Conclusion: Diode cyclophotocoagulation is a useful therapy for the management of glaucoma in children.
Oleuropein inhibits pancreatic cancer through miR-190b-5p induction
Authors: Xu Qian , Huang Xiaobing , Wu Ningzi , Hou Peifeng 
Published: April 2022

Background: Pancreatic cancer has the highest mortality rate of all major cancers. Till now, surgical resection is considered the only potentially curative therapy. The aim of this study was to study oleuropein (Ole) as an alternative treatment for pancreatic cancer.
Methods: First, we determined the tumor-inhibitory effect of Ole in pancreatic cancer cell lines and the KPC mouse model. Second, we employed microarray and real-time polymerase chain reaction to identify microRNAs (miRNA) regulated by Ole in pancreatic cancer. Third, we mapped out the downstream target of the miRNA candidate by luciferase assay and western blotting. Finally, we measured the tissue expression of the miRNA candidate in clinical samples. Both in vitro and in vivo studies supported Ole treatment suppressed pancreatic cancer.
Results: We profiled miRNAs changes induced by Ole and identified miR-190b-5p as a novel functional player in Ole-mediated pancreatic cancer suppression. Further on, we reported that TCF4 in Wnt signaling was a direct target of miR-190b-5p. The suppression of Wnt signaling by miR-190b-5p was attributed to Ole-induced tumor inhibition in a pancreatic cancer model. Finally, we showed that miR-190b-5p was downregulated in human clinical cancer samples.
Conclusion: In summary, we discovered that Ole carried anti-pancreatic cancer function. MiR-190b-5p induced by Ole was a potential therapeutic target.
Uncountably Many Minimal Hereditary Classes of Graphs of Unbounded Clique-Width
Authors: Brignall Robert , Cocks Daniel 
Published: April 2022

Given an infinite word over the alphabet $\{0,1,2,3\}$, we define a class of bipartite hereditary graphs $\mathcal{G}^\alpha$, and show that $\mathcal{G}^\alpha$ has unbounded clique-width unless $\alpha$ contains at most finitely many non-zero letters.
We also show that $\mathcal{G}^\alpha$ is minimal of unbounded clique-width if and only if $\alpha$ belongs to a precisely defined collection of words $\Gamma$. The set $\Gamma$ includes all almost periodic words containing at least one non-zero letter, which both enables us to exhibit uncountably many pairwise distinct minimal classes of unbounded clique width, and also proves one direction of a conjecture due to Collins, Foniok, Korpelainen, Lozin and Zamaraev. Finally, we show that the other direction of the conjecture is false, since $\Gamma$ also contains words that are not almost periodic.
Temporal Analysis of GRB Precursors in the Third Swift-BAT Catalog
Authors: Li Liande , Mao Jirong 
Published: April 2022

Abstract
We select 52 long gamma-ray bursts (GRBs) that have precursor activity in the third Swift-BAT catalog. Each episode shown in both the precursors and the main bursts is fitted by the Norris function. We systematically analyze the temporal properties for both the precursors and the main bursts. We do not find any significant difference between the temporal profile of the precursor and that of the main burst. The photon count of the precursor is related to that of the main burst. It is indicated that the precursor and the main burst might have the same physical origin, as the precursor and the main burst follow the same τ

p
–ω relation. However, we do not find the explicit relation between the energy release of the precursor and the quiescent time. Some theoretical models, such as the fallback collapsar scenario and the jet-cocoon scenario, may be helpful to explain the GRB-precursor phenomena.
Superrotation of Titan’s Stratosphere Driven by the Radiative Heating of the Haze Layer
Authors: Sumi Motoki , Takehiro Shin-ichi , Ohfuchi Wataru , Nomura Hideko , Fujii Yuka 
Published: April 2022

Abstract
Titan’s stratosphere has been observed in a superrotation state, where the atmosphere rotates many times faster than the surface does. Another characteristic of Titan’s atmosphere is the presence of a thick haze layer. In this paper, we performed numerical experiments using a general circulation model to explore the effects of the haze layer on the stratospheric superrotation. We employed a semigray radiation model of Titan’s atmosphere following McKay et al., which takes account of sunlight absorption by the haze particles. The phase change of methane or seasonal changes were not taken into account. Our model with radiation parameters tuned for Titan yielded a global eastward wind around the equator with larger velocities at higher altitudes, except at around 70 km, after 105 Earth days. Although the atmosphere is not in an equilibrium state, the zonal wind profiles are approximately consistent with the observed one. By changing the parameters of the radiation model, we found that the intensity and the location of the maximum zonal wind velocity highly depended on the optical thickness and the altitude of the haze layer, respectively. Analysis of our experiments suggests that the quasi-stationary stratospheric superrotation is maintained by the balance between the meridional circulation decoupled from the surface and the eddies that transport angular momentum equatorward. This is different from, but similar to, the so-called Gierasch mechanism, in which momentum is supplied from the surface. This structure may explain the no-wind region at about 80 km in altitude.