bluuebunny/crossref_metadata_2025_split huggingface dataset:
Le futur du travail en agriculture
Authors: Dedieu Benoît 
Published: November 2022

Nous présentons une synthèse des discussions tenues lors du 2eSymposium international sur le travail en agriculture (29 mars–1eravril 2021). L’objectif est de rendre compte des thématiques et des idées échangées, dans un cadre pluridisciplinaire, et de construire une vision commune du futur du travail agricole à l’échelle mondiale. Les grandes dynamiques de changement structurel opposent, sur le plan du travail, les pays du Nord et du Sud, faisant émerger des questionnements différents (par exemple une agriculture sans agriculteurs dans les pays du Nord,versusun travail décent pour un population active agricole nombreuse dans les pays du Sud). Mais certaines questions sont transversales : la transition agroécologique, le genre, la révolution numérique, les migrations, changent le travail agricole en profondeur. Nous proposons quelques perspectives pour un agenda de recherche pour traiter le futur du travail agricole.
Dimini (Diabetes mellitus? – Ich nicht!): Aktivierung der Gesundheitskompetenz von Versicherten mit erhöhtem Risiko für Diabetes mellitus Typ 2 mittels Coaching in der Vertragsarztpraxis
Authors: Püschner Franziska , Urbanski-Rini Dominika , Dubois Clara , Schliffke Monika , Göhl Martin , Petersen Carsten 
Published: November 2022

Zusammenfassung
Einleitung Lebensstilveränderungen können das Risiko, an Diabetes mellitus Typ 2 (DMT2) zu erkranken, senken. Im Rahmen des Innovationsfondprojektes Dimini (Diabetes mellitus? Ich nicht!) wurde untersucht, ob Menschen mit einem erhöhten Diabetesrisiko frühzeitig und niedrigschwellig in der hausärztlichen Praxis identifiziert werden können und ob die Lebensstilintervention Dimini zu einer verbesserten Gesundheitskompetenz sowie einer Gewichtsreduktion führt.
Methodik Dimini (01NVF17012) wurde vom 1. Juni 2017 bis zum 30. November 2020 in hausärztlichen Praxen in Hessen und in Schleswig-Holstein in Form einer randomisierten kontrollierten Studie umgesetzt. Zum Einschluss der Versicherten führten die Hausärztinnen und Hausärzte u.a. bei metabolisch auffälligen Personen ein Risikoscreening mittels FINDRISK-Tests durch (t0). Der 15-monatige Beobachtungszeitraum umfasste für die Interventionsgruppe eine dreimonatige Lebensstilintervention, optionale Coaching-Termine und drei Kontrolltermine in der Interventions- und Kontrollgruppe, zu denen die Datenerhebung erfolgte. Es wurden u.a. die Endpunkte Körpergewicht, Gesundheitskompetenz und der Grad der Zielerreichung untersucht.
Ergebnisse Von den 3349 Personen, die mit dem FINDRISK gescreent wurden, hatten 1430 (42,8%) Personen ein erhöhtes DMT2-Risiko (FINDRISK ≥ 12). Davon wurden 1170 Personen eingeschlossen. Das Durchschnittsgewicht sank im Interventionsverlauf (t0 zu t3) signifikant um 1,6 kg (1,1%) (V = 106721, p < 0,001). Der Mann-Whitney-U-Test (W = 49265, p = 0,036) zeigte eine signifikant größere Gewichtsabnahme in der Interventionsgruppe (IG) (Mt0-t3 = 2,06 kg, SD = 6,97) als in der Kontrollgruppe (KG) (Mt0-t3 = 1,18 kg, SD = 5,88). Die Gesundheitskompetenz verbesserte sich im Verlauf der Intervention nicht signifikant. 21 Teilnehmende (7,2%) erreichten ihr Gewichtsziel, 55 (18,8%) übertrafen und 217 (74,1%) verfehlten es. Das Ziel, 30 Minuten am Tag aktiv zu sein, erreichten laut eigenen Angaben 177 Teilnehmende (79,4%).
Schlussfolgerung Die Studie zeigt das Potential von flächendeckenden Risikoscreenings zur Früherkennung von Menschen mit erhöhtem DMT2-Risiko sowie einen geringen positiven Effekt der Intervention auf die Gewichtsreduktion. Subgruppenspezifische Präventionsansätze sollten im Anschluss an das Screening angeboten werden. Diese sollten bestehende Strukturen und verschiedene (ärztliche und therapeutische) Disziplinen und Fachrichtungen einbinden. Eine stärkere Ausrichtung des Gesundheitswesens hinsichtlich Gesundheitsförderung und Prävention scheint notwendig.
Accurate prediction of histological grading of intraductal papillary mucinous neoplasia using deep learning
Authors: Schulz Dominik , Heilmaier Markus , Phillip Veit , Treiber Matthias , Mayr Ulrich , Lahmer Tobias , Mueller Julius , Demir Ihsan Ekin , Friess Helmut , Reichert Maximilian , Schmid Roland M. , Abdelhafez Mohamed 
Published: November 2022

Background Risk stratification and recommendation for surgery for intraductal papillary mucinous neoplasm (IPMN) are currently based on consensus guidelines. Risk stratification from presurgery histology is only potentially decisive owing to the low sensitivity of fine-needle aspiration. In this study, we developed and validated a deep learning-based method to distinguish between IPMN with low grade dysplasia and IPMN with high grade dysplasia/invasive carcinoma using endoscopic ultrasound (EUS) images.
Methods For model training, we acquired a total of 3355 EUS images from 43 patients who underwent pancreatectomy from March 2015 to August 2021. All patients had histologically proven IPMN. We used transfer learning to fine-tune a convolutional neural network and to classify “low grade IPMN” from “high grade IPMN/invasive carcinoma.” Our test set consisted of 1823 images from 27 patients, recruiting 11 patients retrospectively, 7 patients prospectively, and 9 patients externally. We compared our results with the prediction based on international consensus guidelines.
Results Our approach could classify low grade from high grade/invasive carcinoma in the test set with an accuracy of 99.6 % (95 %CI 99.5 %–99.9 %). Our deep learning model achieved superior accuracy in prediction of the histological outcome compared with any individual guideline, which have accuracies between 51.8 % (95 %CI 31.9 %–71.3 %) and 70.4 % (95 %CI 49.8–86.2).
Conclusion This pilot study demonstrated that deep learning in IPMN-EUS images can predict the histological outcome with high accuracy.
Advanced serrated polyps as a target of screening: detection rate and positive predictive value within a fecal immunochemical test-based colorectal cancer screening population
Authors: van Toledo David E. F. W. M. , Breekveldt Emilie C. H. , IJspeert Joep E. G. , van Vuuren Anneke J. , van Kemenade Folkert J. , Ramakers Christian , Nagtegaal Iris D. , van Leerdam Monique E. , Spaander Manon C. W. , Lansdorp-Vogelaar Iris , Toes-Zoutendijk Esther , Dekker Evelien 
Published: November 2022

Background Advanced serrated polyps (ASPs) have a comparable risk to advanced adenomas for progression to colorectal cancer (CRC). The yield of most CRC screening programs, however, is based on advanced adenomas and CRC only. We assessed the ASP detection rate, and positive predictive value (PPV) including ASPs in a fecal immunochemical test (FIT)-based screening program.
Methods We analyzed the findings of follow-up colonoscopies of FIT-positive screenees in the Dutch CRC screening program from 2014 until 2020. Data were retrieved from the national screening and pathology database. An ASP was defined as any serrated polyp of ≥ 10 mm, sessile serrated lesion with dysplasia, or traditional serrated adenoma. The ASP detection rate was defined as the proportion of colonoscopies with ≥ 1 ASP. PPV was originally defined as the proportion of individuals with a CRC or advanced adenoma. The updated PPV definition included CRCs, advanced adenomas, and/or ASPs.
Results 322 882 colonoscopies were included in the analyses. The overall detection rate of ASPs was 5.9 %. ASPs were detected more often in women than men (6.3 % vs. 5.6 %; P < 0.001). ASP detection rates in individuals aged 55–59, 60–64, 65–69, and 70 + were 5.2 %, 6.1 %, 6.1 %, and 5.9 %, respectively (P < 0.001). The PPV for CRCs and advanced adenomas was 41.1 % and increased to 43.8 % when including ASPs. The PPV increase was larger in women than in men (3.2 vs. 2.4 percentage points).
Conclusions 5.9 % of FIT-positive screenees had ASPs, but half of these were detected in combination with a CRC or advanced adenoma. Therefore, including ASPs results in a small increase in the yield of FIT-based screening.
Complications during Induction Chemotherapy in Acute Promyelocytic Leukemia: An Institutional Experience
Authors: Yedla Rajani Priya , Bala Stalin Chowdary , Pydi Venkateswara Rao , Chennamaneni Rachana , Kuruva Siva Prasad , Konatam Meher Lakshmi , Gundeti Sadashivudu 
Published: November 2022

Introduction Acute promyelocytic leukemia (APL) has transformed from a highly fatal disease to a highly curable one. Induction deaths continue to represent one of the major impediments in modern therapy of APL. Sepsis, hemorrhage, and differentiation syndrome are the major complications during induction therapy in APL. The present study reports the incidence and prognostic factors of major complications during induction chemotherapy in patients with newly diagnosed APL.
Materials and Methods The present study was a single institutional, observational, retrospective study. All cases of APL diagnosed by morphology and confirmed by RT PCR (PML RARα) were included in this study. Data were analyzed using Statistical Package for the Social Sciences (SPSS) version 25.
Results A total of 73 patients were analyzed. The median age at presentation was 30 years (range, 3–60 years) with a female to male ratio of 1.02:1. The most common symptom at presentation was fever (80%), followed by fatigue (56%) and gum bleeding (37%). The majority of the patients at presentation were high risk (42.4%), followed by intermediate risk (38.4%) and low risk (19.2%). Fifty-seven (78%) patients achieved complete hematological remission and 16 (22%) succumbed during induction chemotherapy. Infection was the most common cause of induction death (50%), followed by hemorrhage (37.5%) and differentiation syndrome (12.5%). On univariate analysis of prognostic factors, bcr3 variant, grade 3/4 bleeding during induction, and low levels of albumin at presentation were significant for induction mortality (p = 0.034, 0.041, and 0.008 respectively). On multivariate analysis, only serum albumin < 3.5 g/dL was an independent predictor for induction mortality (p = 0.043).
Conclusion The majority of patients were high risk at presentation. Sepsis was the most common complication during induction and also the leading cause of induction death. Identifying induction complications at the earliest and providing aggressive supportive measures can further improve outcomes in APL.
Clinical Outcomes of Uterine Body Cancers Treated in a Tertiary Cancer Center
Authors: Muthulingeshkumar K. , Pandjatcharam Jagadesan , Chaturvedula Latha 
Published: November 2022

Objectives This article reports the clinical outcomes of uterine body cancers in South Indian population. The primary outcome of our study was overall survival (OS). The secondary outcomes were disease-free survival (DFS), patterns of recurrence, toxicities of radiation treatment, and the association of patient, disease, and treatment characteristics with survival and recurrence.
Materials and Methods Records of the patients diagnosed as malignancy in uterus and treated with surgery alone or with adjuvant treatment from January 2013 to December 2017 were retrieved after Institute Ethics Committee approval. Demographic, surgical, histopathology, and adjuvant treatment details were retrieved. Patients of endometrial adenocarcinoma were stratified according to the European Society of Medical Oncology/European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology consensus for analysis and overall outcomes irrespective of histology were also analyzed.
Statistical Analysis For the survival analysis, Kaplan–Meier survival estimator was used. Cox regression was used to test the significance of association of factors with outcomes in terms of hazard ratio (HR).
Results A total of 178 patient records were retrieved. The median follow-up of all patients was 30 months (0.5–81 months). The median age of the population was 55 years. Most common histology was endometrioid type of adenocarcinoma (89%), sarcomas comprised only 4%. The mean OS of all patients was 68 months (n = 178), median was not reached. Five-year OS was 79 %. Five-year OS rates observed in low, intermediate, high-intermediate, and high-risk were 91, 88, 75, and 81.5%, respectively. The mean DFS was 65 months, median not reached. The 5-year DFS was 76%. The 5-year DFS rates observed were 82, 95, 80, and 81.5% for low, intermediate, high-intermediate, and high-risk, respectively. Univariate analysis using Cox regression showed increase in hazard for death in case of node positivity, HR 3.96 (p 0.033). The HR for disease recurrence was 0.35 (p = 0.042) in patients who had received adjuvant radiation therapy. No other factors had any significant impact on death or disease recurrence.
Conclusion The survival outcomes in terms of DFS and OS were comparable with other Indian and Western data reported in the published literature.
Improving the User Experience with Discount Site-Specific User Testing
Authors: Pierce Robert P. , Eskridge Bernie R. , Ross Brandi , Day Margaret A. , Dean Brooke , Belden Jeffery L. 
Published: November 2022

Abstract
Objectives Poor electronic health record (EHR) usability is associated with patient safety concerns, user dissatisfaction, and provider burnout. EHR certification requires vendors to perform user testing. However, there are no such requirements for site-specific implementations. Health care organizations customize EHR implementations, potentially introducing usability problems. Site-specific usability evaluations may help to identify these concerns, and “discount” usability methods afford health systems a means of doing so even without dedicated usability specialists. This report characterizes a site-specific discount user testing program launched at an academic medical center. We describe lessons learned and highlight three of the EHR features in detail to demonstrate the impact of testing on implementation decisions and on users.
Methods Thirteen new EHR features which had already undergone heuristic evaluation and iterative design were evaluated over the course of three user test events. Each event included five to six users. Participants used think aloud technique. Measures of user efficiency, effectiveness, and satisfaction were collected. Usability concerns were characterized by the type of usability heuristic violated and by correctability.
Results Usability concerns occurred at a rate of 2.5 per feature tested. Seventy percent of the usability concerns were deemed correctable prior to implementation. The first highlighted feature was moved to production despite low single ease question (SEQ) scores which may have predicted its subsequent withdrawal from production based on post implementation feedback. Another feature was rebuilt based on usability findings, and a new version was retested and moved to production. A third feature highlights an easily correctable usability concern identified in user testing. Quantitative usability metrics generally reinforced qualitative findings.
Conclusion Simplified user testing with a limited number of participants identifies correctable usability concerns, even after heuristic evaluation. Our discount usability approach to site-specific usability has a role in implementations and may improve the usability of the EHR for the end user.
Marine self-potential measurement tool for autonomous underwater vehicle
Authors: Song Sixuan , Deng Xianming , Su Zhaoyang , Deng Ming , Chen Kai 
Published: November 2022

Marine self-potential (SP) measurement is commonly conducted for seafloor sulfide detection and hydrothermal vent studies in deep water using instruments towed close to the seafloor. However, this method has the following shortcomings: (1) It relies on ships for deep towing, and the need for a dedicated ship time lowers its efficiency. (2) Owing to complex topography, most towed instruments are located far from the seafloor to ensure safety, resulting in large effective signal attenuation and low signal-to-noise ratio. (3) The measurement direction is generally a single axis, with only the electric field of the axial component observed, providing limited information. With the gradual maturity of autonomous underwater vehicle (AUV) technology, it has become possible to mount marine SP measurement tools on AUVs for detection. Compared with conventional methods, this method has significant advantages in terms of efficiency, signal-to-noise ratio, and multicomponent observation. The proposed tool is a lightweight underwater device having a compact design and low power consumption, making it suitable for AUVs. The overall volume of the tool is D50 mm × L350 mm, and the underwater weight is 0.6 kg. Chopper amplification technology ensures the low-noise measurement of electric field signals. In addition, the reformed electrodes enhance stability, thereby reducing the mechanical vibration noise. Laboratory test results show that the noise of the data logger is 7.8 nV/rt (Hz)@1 Hz. The marine test conducted in the southwest Indian Ocean verified the reliability of the proposed marine SP measurement tool. The maximum working depth was 4000 m. The test lasted ∼25 h, and the effective electric field data were collected for ∼17 h. This survey found a maximum SP anomaly of 0.55 mV/m in the Yuhuang hydrothermal field, which provided effective data support for the discovery of new seafloor sulfide anomalies.
System-on-chip approach microwave imaging reflectometer on DIII-D tokamak
Authors: Zhu Y. , Chen Y. , Yu J.-H. , Domier C. , Yu G. , Liu X. , Kramer G. , Ren Y. , Diallo A. , Luhmann N. C. , Li X. 
Published: November 2022

System-on-chip millimeter wave integrated circuit technology is used on the two-dimensional millimeter-wave imaging reflectometer (MIR) upgrade for density fluctuation imaging on the DIII-D tokamak fusion plasma. Customized CMOS chips have been successfully developed for the transmitter module and receiver module array, covering the 55–75 GHz working band. The transmitter module has the capability of simultaneously launching eight tunable probe frequencies (&gt;0 dBm output power each). The receiver enclosure contains 12 receiver modules in two vertical lines. The quasi-optical local oscillator coupling of previous MIR systems has been replaced with an internal active frequency multiplier chain for improved local oscillator power delivery and flexible installation in a narrow space together with improved shielding against electromagnetic interference. The 55–75 GHz low noise amplifier, used between the receiver antenna and the first-stage mixer, significantly improves module sensitivity and suppresses electronics noise. The receiver module has a 20 dB gain improvement compared with the mini-lens approach and better than −75 dBm sensitivity, and its electronics noise temperature has been reduced from 55 000 K down to 11 200 K. The V-band MIR system is developed for co-located multi-field investigation of MHD-scale fluctuations in the pedestal region with W-band electron cyclotron emission imaging on DIII-D tokamak.
Validation of a torsional balance for thrust measurements of Hall effect and microwave-based space propulsion systems
Authors: Masillo S. , Stubbing J. , Swar K. , Staab D. , Garbayo A. , Lucca Fabris A. 
Published: November 2022

A torsional thrust balance has been designed and validated by Surrey Space Centre and Added Value Solutions UK Ltd. in collaboration with the UK Space Agency. The thrust stand has been tested with two electric propulsion (EP) systems operating with xenon: the Halo thruster and the XJET thruster. The first consists of a low-power (&lt;1 kW) Hall effect-based thruster, whose thrust level is between 3 and 20 mN, depending on the power of the system. The second is an electron cyclotron resonance thruster whose operative point is in the 0.3–1.5 mN thrust range. The thruster is mounted on a titanium rotating beam, whose movement is measured by an optical fiber displacement sensor. The thrusters’ direct current electrical connections are routed through room temperature liquid metal pots and microwave power is transmitted via a wireless transfer system, minimizing friction effects. To reduce thermal issues during long thruster operations, the torsional thrust balance is designed with a water-cooling hub around the flex pivot. Noise from the laboratory environment is lessened by using four vibration-dampening spring systems as thrust balance feet. The tests on the two EP systems have shown accurate and repeatable results, demonstrating that the balance can be used to characterize different EP systems in the μN–mN thrust range.
Spectroscopic detection of the stannylidene (H2C=Sn and D2C=Sn) molecule in the gas phase
Authors: Smith Tony C. , Gharaibeh Mohammed , Clouthier Dennis J. 
Published: November 2022

The H2CSn and D2CSn molecules have been detected for the first time by laser-induced fluorescence (LIF) and emission spectroscopic techniques through the B̃1B2−X̃1A1 electronic transition in the 425–400 nm region. These reactive species were prepared in a pulsed electric discharge jet using (CH3)4Sn or (CD3)4Sn diluted in high-pressure argon. Transitions to the electronic excited state of the jet-cooled molecules were probed with LIF, and the ground state and low-lying Ã1A2 state energy levels were measured from single vibronic level emission spectra. We supported the experimental studies by a variety of ab initio calculations that predicted the energies, geometries, and vibrational frequencies of the ground and lower excited electronic states. The spectroscopy of stannylidene (H2CSn) is in many aspects similar to that of silylidene (H2CSi) and germylidene (H2CGe).
Intimacy in online classrooms
Authors: Dobinson Toni 
Published: November 2022

Abstract
In this article I describe the transition of a group of university students in Australia into an online learning environment during COVID-19 pandemic disruptions. I reflect upon my intersubjective experiences as the lecturer in an unexpected situation of urgency and physical distancing. Research has acknowledged synchronous virtual learning contexts as less psychologically distancing than previously thought. I argue that these contexts can foster profound intimacy between participants through linguistic and multimodal means. I use an auto-ethnographic narrative inquiry approach to share observations gained retrospectively through multimodal, critically reflexive, social semiotic discourse analysis of audio-visual recordings of synchronous workshops conducted in 2020. I attempt to fill the gap in research on intimacy in online educational settings by suggesting that intimacy can be created by linguaplay, personal testimonies, and contrived chaotic material ecologies. I advocate moving away from an obsession with standardising and generating student knowledge in formal online learning to a stance that values intimacy, connection, and spontaneity.
Thematic patterns, Cognitive Discourse Functions, and genres
Authors: Wu Yanming (Amy) , Lin Angel M. Y. 
Published: November 2022

Abstract
As CLIL is developing into an established discipline, it is timely to deepen the theorizing of integration of content and language, particularly in CLIL assessment. To illustrate the challenges, a representative example of a high-stakes CLIL biology assessment task in Hong Kong will first be presented. An Integrative Model for CLIL will then be proposed and applied to illuminate the demands of the assessment task and diagnose a sample student performance. The Integrative Model is developed by integrating genre and register theory (Martin & Rose, 2008), Cognitive Discourse Functions (Dalton-Puffer, 2013), thematic patterns theory (Lemke, 1990), Concept-and-Language-Mapping (CLM) Approach (He & Lin, 2019) and translanguaging/trans-semiotizing theories (Garcia & Li, 2014; Lin, 2019). To further illustrate the utility of the Model, a range of possible assessment-for-learning (Black et al., 2003) CLIL task examples designed by the authors will be presented. The article will conclude with implications for CLIL pedagogy and assessment.