bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Original and Short Versions of the Activities-Specific Balance Confidence (ABC) Scale in Community-Dwelling Older Adults: Clinical Implications Based on Scale Agreement, Internal Consistencies, and Associations With Self-Rated Health
Authors: Tiernan Chad , Goldberg Allon 
Published: March 2022

Background and Purpose:
Balance confidence assessment in older adults has implications for falls prevention and quality of life. It remains unclear whether the original Activities-specific Balance Confidence Scale (ABC-16) or the shortened 6-item scale (ABC-6) is recommended clinically. This study examined ABC-16 and ABC-6 association and agreement, internal consistencies, and relationships with self-rated health (SRH) in community-dwelling older adults.

Methods:
Secondary analysis of an existing dataset (N = 77) was performed. Scale association and agreement were assessed with a Spearman ρ correlation (r
s), intraclass correlation coefficient, 95% limits of agreement (LoA), and Bland-Altman plot. Cronbach α values were calculated to determine internal consistencies. Separate multiple linear regression models with SRH as the outcome and ABC-6 and ABC-16 scores as primary predictors were estimated and subsequently used to conduct Hotelling t test.

Results and Discussion:
Participants were primarily female (80.5%) with a median age of 68 years living in the metro Detroit area. The ABC-6 and ABC-16 were closely associated [r
s = 0.97, P < .001; intraclass correlation coefficient (2,1) = 0.80] but demonstrated discrepancy (95% LoA range of −3.9 to +18.2; mean difference = 7.2 points in the direction of the ABC-16). Cronbach α values were 0.95 (ABC-16) and 0.89 (ABC-6). Regression model 1 (ABC-6 = primary predictor) explained more of the variance (R
2 = 0.36) in SRH compared with model 2 (ABC-16 = primary predictor; R
2 = 0.29). Hotelling t test [t(74) = 2.4, P = .008] found that the predicted values from the ABC-6 model were significantly more highly correlated with SRH than those from the ABC-16 model.

Conclusions:
Despite a high correlation between the ABC-16 and ABC-6, the 2 scales showed limited agreement and should not be considered interchangeable. Given that the ABC-16 takes longer to administer, does not relate to SRH as strongly, and could have redundant items, the ABC-6 may be preferable to the ABC-16 for balance confidence assessment in older adults living in cold weather, urban, or well-resourced areas.
PENDAMPINGAN PADA MASYARAKAT DALAM PENGEMBANGAN MATA PENCAHARIAN MELALUI PEMBERDAYAAN KOMUNITAS PEMUDA DESA DI DESA LAU KECAMATAN DAWE KABUPATEN KUDUS
Authors: Lestari Eta Yuni , Sunarto Slamet , Wijayanti Tutik 
Published: March 2022

Setiap desa pada dasarnya memiliki potensi yang dapat dijadikan sebagai peluang untuk mempercepat pembangunan masyarakat desa. Masing-masing kepala desa hingga kepala daerah memiliki tanggungjawab untuk melaksanakan pembangunan sebagai wujud tugas tambahan dalam melaksanakan prinsip otonomi daerah. Pemerintah daerah menjadi sala satu landasan perubahan sistem tata pengaturan atau tata pemerintahan (governance system) yang penting dalam sejarah pembangunan politik dan pengelolaan administrasi pemerintah secara nasional. Salah satu permasalahan yang dialami oleh masyarakat desa di desa Lau Kecamatan Dawe Kabupaten Kudus adalah adanya ketimpangan antara satu desa dengan desa yang lain Pemuda di desa Lau sebagian besar bekerja sebagai buruh pabrik rokok bagi kaum perempuan, dan buruh bangunan bagi kaum laki-laki, berbeda dengan masyarakat di desa Colo dimana mata pencaharian lebih beragam. Maka diperlukan kegiatan pendampingan untuk mengembangkan mata pencaharian bagi masyarakat desa khususnya pemuda desa Lau Kecamatan Dawe Kabupaten Kudus. Permasalahan yang dialami mitra adalah , pertama Masyarakat desa belum memiliki keterampilan lain selain menjadi buruh pabrik maupun buruh bangunan, kedua masyarakat Desa Lau telah memiliki komunitas remaja akan tetapi tidak aktif melakukan kegiatan. Ketiga, Masyarakat Desa Lau jarang sekali mendapatkan pelatihan dari dinas, maupun perguruan tinggi . Ke empat Masyarakat desa Lau belum memiliki kemampuan kewirausahaan. Tahapan kegiatan pengabdian dilaksanakan dengan perencanaan kegiatan, pelaksanaan kegiatan dan evaluasi.
Growth hormone therapy in short-stature patients with kyphoscoliosis: a literature review
Authors: Alharbi Mariam S 
Published: March 2022

The aim of the study was to conduct a literature review on growth hormone therapy in short-stature patients with kyphoscoliosis.
The search strategy was performed in which all the relevant papers published in 20 years were included on Pub Med, Central, and Google scholar by using keywords short stature, growth hormones, adverse events of growth hormones in kyphoscoliosis, safety.
The study investigation supports the idea that giving human growth hormone (HGH) to a diverse population of short-statured children does not enhance the occurrence of scoliosis.
Patients on HGH therapy for progressing scoliosis had syndromes in which scoliosis was more prevalent in an age-matched group. Short stature attributed to progressive growth failure is prevalent in all mucopolysaccharidosis (MPS) disorders, as per the existing research on growth and growth hormone in MPS.
MPS should be explored in children who are being tested for short stature since growth failure might be the presenting symptom.
Surgical management options for long-bone metastasis
Authors: Cirstoiu Catalin , Cretu Bogdan , Iordache Sergiu , Popa Mihnea , Serban Bogdan , Cursaru Adrian 
Published: March 2022

Bone metastases are difficult to treat surgically, necessitating a multidisciplinary approach that must be applied to each patient depending on the specifics of their case.
The main indications for surgical treatment are a lack of response to chemotherapy, radiation therapy, hormone therapy, immunotherapy, and bisphosphonates which is defined by persistent pain or tumor progression; the risk of imminent pathological bone fracture; and surgical treatment for single bone metastases.
An important aspect of choosing the right treatment for these patients is accurately estimating life expectancy. Improved chemotherapy, postoperative radiation therapy, and sustainable reconstructive modalities will increase the patient’s life expectancy.
The surgeon should select the best surgical strategy based on the primary tumor and its characteristics, the presence of single or multiple metastases, age, anatomical location, and the functional resources of the patient.
Preventive osteosynthesis, osteosynthesis to stabilize a fracture, resections, and reconstructions are the main surgical options for bone metastases.
Resection and reconstruction with a modular prosthesis remain the generally approved surgical option to restore functionality, increase the quality of life, and increase life expectancy.
Preoperative embolization is necessary, especially in the case of metastases of renal or thyroid origin. This procedure is extremely important to avoid complications, with a major impact on survival rates.
How the Asian and European Communities Accept Negative Numbers
Authors: Maryati Tita Khalis , Aisah K , Miftah Ramdani 
Published: March 2022

AbstractThis research is based on several inquiries from mathematics educators on the origins of negative numbers and their acceptance in the community. This study used library research, or more precisely, bibliographical studies, as a method. The research examined how the Asian and European communities accept negative numbers. The study's findings indicated that the Asian and European communities accept negative numbers differently. In comparison to the Asian population, the European populace takes a long time to accept negative figures. It resulted in numerous contrasts between the Asian and European Communities, one of which is in terms of religiosity. This study established that religiosity has an effect on the Asian and European communities' acceptance of negative numbers.AbstrakPenelitian ini didasarkan pada beberapa pertanyaan dari pendidik matematika tentang asal-usul bilangan negatif dan penerimaannya di masyarakat. Penelitian ini menggunakan metode penelitian kepustakaan atau lebih tepatnya studi kepustakaan. Penelitian tersebut mengkaji bagaimana masyarakat Asia dan Eropa menerima angka negatif. Temuan studi menunjukkan bahwa komunitas Asia dan Eropa menerima angka negatif secara berbeda. Dibandingkan dengan penduduk Asia, penduduk Eropa membutuhkan waktu lama untuk menerima angka negatif. Hal ini mengakibatkan banyak perbedaan antara Komunitas Asia dan Eropa, salah satunya dalam hal religiositas. Studi ini menetapkan bahwa religiusitas berpengaruh pada penerimaan masyarakat Asia dan Eropa terhadap angka negatif. How to Cite: Maryati, T. K., Aisah, K., Miftah, R. (2021). How the Asian and European Communities Accept Negative Numbers. TARBIYA: Journal of Education in Muslim Society, 8(2), 167-178. doi:10.15408/tjems.v8i2.25042.
Changes in molecular epidemiology of carbapenem-resistant Klebsiella pneumoniae in the intensive care units of a Greek hospital, 2018–2021
Authors: Zarras Charalampos , Pappa Styliani , Zarras Konstantinos , Karampatakis Theodoros , Vagdatli Eleni , Mouloudi Eleni , Iosifidis Elias , Roilides Emmanuel , Papa Anna 
Published: March 2022

Abstract
The spread of multi-drug resistant (MDR) Gram-negative bacteria, including Klebsiella pneumoniae, constitutes a global threat. The most frequent mechanism of acquired carbapenem resistance is the production of carbapenemases, especially KPC, NDM, VIM, IMP and OXA-48. We analyzed the epidemiological trend of carbapenem resistance genes of carbapenem-resistant K. pneumoniae (CRKP) strains isolated from critically ill patients in a Greek tertiary hospital.
The study included 150 CRKP isolates collected from 116 (77.4%) patients hospitalized in the adult ICU and 17 (11.3%) each in the pediatric and the two neonatal ICUs between March 2018 and March 2021. Identification and antimicrobial susceptibility testing were performed using VITEK-2. A multiplex lateral flow immunoassay was used for the detection of carbapenemases, while the detection of bla
VIM, bla
KPC, bla
NDM, bla
IMP and bla
OXA-48-like genes was achieved by multiplex PCR.
The bla
NDM was mainly detected in adults (54/116, 46.9%), while in children the most often detected gene was bla
KPC (24/34, 70.6%). The predominant carbapenem resistance gene during 2018–2019 was bla
KPC alone or in combination with bla
VIM, reaching 44.4% in 2019, while during 2020–2021 the detection of bla
NDM prevailed significantly, reaching 45.5 and 60.7% for 2020 and 2021, respectively.
A shift in the molecular epidemiology of CRKP was seen during 2018–2021, which is probably associated with the recent excessive empiric use of newer antimicrobials. Surveillance studies and proper and strict implementation of infection control measures are highly needed to decrease the spread of MDR bacteria, including CRKP.
Datos online no-solicitados en Twitter y toma de decisiones en políticas públicas sobre el uso de sustancias psicoactivas en Colombia
Authors: Peña Enrique , Fontes Carlos 
Published: March 2022

Hoy en día observamos cómo muchas de las actividades humanas cotidianas se han trasladado desde el mundo material al mundo digital y con ellas los datos que generan. Entre estas nuevas relaciones digitales se destacan las interacciones comerciales, nuevas relaciones laborales derivadas del incremento del trabajo virtual remoto y novedosas formas de relacionamiento y convivencia social facilitadas por una amplia gama de tecnologías, entre ellas las redes sociales como Facebook, Twitter e Instagram. Cada vez que se tiene acceso a más y mejor tecnología al servicio de la sociedad, los Estados y organismos privados pueden verse beneficiados por este nuevo paradigma a la hora de cumplir sus objetivos sociales. Estamos en una era en donde el énfasis se trasladó de la generación de datos hacia el procesamiento de estos en grandes volúmenes. Entre las distintas herramientas que generan datos online no solicitados y para el análisis del presente escrito se destaca la plataforma Twitter, red social de uso gratuito de comunicación bidireccional que ha sido el centro de distintos ejercicios políticos a lo largo del mundo, usada por muchos políticos de Occidente y que se caracteriza por tener una interfaz de consulta masiva de datos, apta para centros que pretenden análisis social.
En el siguiente documento se pretende evidenciar a partir de dos ejemplos prácticos (análisis de Word Cloud y análisis de sentimientos), como el uso del Application Programming Interface (API) de Twitter puede arrojar información útil para mejorar la toma de decisión en políticas públicas, aplicable a temas específicos de difícil enfoque como por ejemplo el uso de sustancias psicoactivas en la sociedad. Los datos obtenidos, debidamente procesados, permitirán un mejor contexto de partida para la toma de decisiones, contexto que suele estar ensombrecido por las dinámicas propias del prohibicionismo en las políticas de drogas.
VALORACIÓN DE SEMILLAS Y PLANTAS NATIVAS DE LA COMARCA GUNAYALA, REPÚBLICA DE PANAMÁ
Authors: Morales Lenin Alfonso , Castillo Geodisio 
Published: March 2022

Este artigo tem o objetivo de descrever as sementes e plantas nativas que estão sendo perdidas por não serem consumidas, utilizadas ou cultivadas pelo povo Gunadule na Comarca Gunayala, Panamá. A metodologia estabelecida baseou-se em diálogos participativos, por meio de pesquisas com questões abertas, além de visita de campo. A abordagem do artigo possui duas seções, na primeira seção descreve a metodologia, a área onde a pesquisa foi realizada, a idade e o número de participantes por comunidade. Em relação à segunda seção, apresentar os resultados desse processo investigativo.Palavras-chaveGunayala. Plantas Nativas. Nainu. Producão Agricola. Semientes Nativas. ResumenEste artículo tiene como objetivo describir las semillas y plantas nativas que se están perdiendo por no ser consumido, utilizados o cultivadas por parte del pueblo Gunadule en la Comarca de Gunayala, Panamá. La metodología establecida, se basó en diálogos participativos, a través de encuestas con preguntas abiertas así mismo con visita a campo. El abordaje del artículo tiene dos secciones, en su primera sección describir la metodología, el área donde se realizó la investigación, la edad y cantidad de participantes por comunidad. Respecto a la segunda sección, presentar los resultados de este proceso investigativo. KeywordsGunayala. Plantas Nativas. Nainu. Producción Agrícola. Semillas Nativas.
MACROSCOPIC FUNGI USED BY INDIGENOUS PEOPLE IN BRAZIL: A REVIEW OF AND PERSPECTIVES ON THE CULTI-VATION OF EDIBLE SPECIES
Authors: Putzke Jair , Santos Aline Bezerra da Silva , Castro Renata Machado , Putzke Marisa Terezinha Lopes 
Published: March 2022

O conhecimento acerca de uso de fungos pelos povos indígenas brasileiros ainda é escasso e necessita ser investigado. Muitas espécies não estão em listas e seus usos podem significar alternativas de cultivo inclusive em escala comercial. Realizando um levantamento do que já se publicou sobre uso de fungos por diferentes etnias indígenas do Brasil, elaborou-se uma lista de espécies e potenciais de cultivo para cada taxon. Encontrou-se o primeiro relato de 1560 e há um total de 45 espécies identificadas atualmente, 10 a mais do que no último levantamento realizado. 14 gêneros são discutidos com potencial de cultivo comercial, destacando-se Polyporus indigenus e Polyporus sapurema. Para todas as espécies as necessidades ambientais e nutricionais são apresentadas de modo a facilitar o cultivo aos interessados.Palavras-chavecogumelos; nutrição; ameríndios; etnomicologia. AbstractKnowledge on the use of fungi by indigenous people in Brazil is still scarce and needs to be better investigated. Many species are not recorded and their uses could lead to alternatives for cultivation, even on a commercial scale. By conducting a survey of what has already been published on the use of fungi by different indigenous ethnic groups in Brazil, we prepared a list of species and cultivation potential for each taxon. We found a total of 1560 records; a total of 45 species are currently identified, 10 more than registered in a previous survey. Fourteen genera are reviewed for their potential for commercial cultivation, with an emphasis on Polyporus indigenus and Polyporus sapurema. For all species, environmental and nutritional needs are presented below to facilitate the cultivation of these species for those who are interested. Keywordsmushrooms; nutrition; Amerindians; ethnomycology
Mechanism and Potential Therapy in Ameloblastoma: Akt Signaling Pathway
Authors: Hadi Steward , Porjo Leo Alberto , Sandra Ferry 
Published: March 2022

BACKGROUND: Ameloblastoma is the most common benign aggressive tumor. They are more prevalent in the mandible than in the maxilla, mostly observed on the posterior of the jaw. Ameloblastoma can arise at any age, however it most usually affect patients between the ages of 20 and 40. Numerous efforts have been made to develop molecular targeted therapies to treat cancers, such as Akt inhibitors. However, these drugs have not been tested for treating ameloblastoma yet, since underlying molecular factors have yet to be identified. This study was carried out to delineate possible molecular mechanisms related to the Akt signaling pathway in ameloblastoma and potential drugs for ameloblastoma treatment. CONTENT: Akt signaling pathway in ameloblastoma has been implicated in the formation and progression of tumors. Akt signaling is involved in various cellular mechanisms, such as cell cycle, apoptosis, and cytoskeletal rearrangement, which includes Phosphatidyl Inositol 3 Kinase (PI3K)-Akt signaling, Akt-Nuclear Factor (NF)-κB signaling, Akt-Mammalian Target of Rapamycin (mTOR) signaling, Akt-B-cell Lymphoma (Bcl)-2 Family signaling, Akt-Survivin signaling. Potential ways of treatments using chemical compounds and micro RNA (miRNA), and Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) were explored as well.SUMMARY: The present review highlights various Akt signaling involved in ameloblastoma and its potential pathways for treatments, while the gold standard of ameloblastoma treatment is still surgery to remove the tumor, there are many potential agents through various means of inhibition for ameloblastoma. Therefore, understanding the underlying signaling on ameloblastoma is necessary to induce inhibition on ameloblastoma. More research in potential ways to inhibit Akt signaling in ameloblastoma will lead to a better management of ameloblastoma in the future. KEYWORDS: ameloblastoma, Akt, PI3K, NFkB, mTOR, Bcl-2, miRNA, CRISPR
The effectiveness of oxytetracycline in the treatment of calves with contracted flexor tendons
Authors: Leech Antonia 
Published: March 2022

PICO question
In neonatal calves with contracted flexor tendons is the use of a 3 day course of oxytetracycline in conjunction with other treatments more effective in returning the hoof to normal full weight bearing on both the toe and heel compared to no oxytetracycline?

Clinical bottom line
Category of research question
Treatment
The number and type of study designs reviewed
Three papers were critically reviewed. One randomised controlled study, one case series and one case study
Strength of evidence
Weak
Outcomes reported
Oxytetracycline as a treatment for contracted flexor tendons in calves was found to be slightly more effective in returning the hoof to normal weight bearing compared to no oxytetracycline. In contrast, oxytetracycline infusions for the treatment of contracted flexor tendons in calves do not have an influence on weight bearing and have no significant clinical effect
Conclusion
There was limited confidence that the estimated effect reported by the studies were close to the true effect, this is due to the studies having a number of limitations as well as the case series / study having limited evidentiary power. There is currently insufficient evidence from the literature to support or reject the use of oxytetracycline in the treatment of contracted flexor tendons in calves. Further studies, with higher strengths of evidence, are required to provide conclusive evidence

How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
Revisiting Cemented Femoral Fixation in Hip Arthroplasty
Authors: Khanuja Harpal S. , Mekkawy Kevin L. , MacMahon Aoife , McDaniel Claire M. , Allen Donald A. , Moskal Joseph T. 
Published: March 2022

➤ The primary means of femoral fixation in North America is cementless, and its use is increasing worldwide, despite registry data and recent studies showing a higher risk of periprosthetic fracture and early revision in elderly patients managed with such fixation than in those who have cemented femoral fixation.➤ Cemented femoral stems have excellent long-term outcomes and a continued role, particularly in elderly patients.➤ Contrary to historical concerns, recent studies have not shown an increased risk of death with cemented femoral fixation.➤ The choice of femoral fixation method should be determined by the patient’s age, comorbidities, and bone quality.➤ We recommend considering cemented femoral fixation in patients who are >70 years old (particularly women), in those with Dorr type-C bone or a history of osteoporosis or fragility fractures, or when intraoperative broach stability cannot be obtained.
Research on Rock Crack Classification Based on Acoustic Emission Waveform Feature Extraction Technology
Authors: Ding Ziwei , Li Xiaofei , Tang Qingbao , Jia Jindui , Gao Chengdeng , Wang Shaoyi 
Published: March 2022

Abstract
Rock fracture mode has practical significance for the prediction and prevention of engineering disasters, and the inversion of fracture mode by the waveform signal not only reduces the experimental error of the mechanical strength measurement but also simplifies the type and quantity of disaster prediction source data. For the relationship between crack mode and mechanical strength, the acoustic emission (AE) waveform signal is studied. Six coarse-grained sandstone samples were tested by uniaxial compression, AE, and scanning electron microscopy. The results show that the number of microhole cracks in rock is positively correlated with tensile-shear cracks and negatively correlated with mechanical strength. The quadratic function regression curve of the proportion of shear cracks and mechanical strength is more realistic. When crack ratio is less than 0.31, the number of shear cracks is positively correlated with the mechanical strength and vice versa. The waveform mutation coefficient k is defined as the overall change description. It is found that the increase of signal mutation has a positive impact on the mechanical strength of rock. The fitting function of crack and the signal mutation near the peak of rock can be divided into six risk zones in a two-dimensional plane. In addition to these exciting results and discoveries, the determination of the number of tensile-shear cracks and its relationship with mechanical strength provide innovative methods and ideas for crack pattern discrimination and rock burst risk assessment of roadway surrounding rock.