bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Multiwalled Carbon Nanotubes in Polytetrafluoroethylene on the Parameters of Electronic Structure and Absorption of UHF Radiation
Authors: Galstian Iryna , Tsapko Yevgen , Makarenko Olexiy , Yampolskiy A.L. 
Published: January 2022

Abstract
Using the methods of angular correlation of annihilation radiation, attenuation of electromagnetic radiation in 1.5–2 2 GHz frequency range, and optical ellipsometry, it was shown that a 2% decrease in the probability of annihilation of positrons in pores of free volume leads to changes in the parameters of electronic structure of composites by 15–25% in composites of polytetrafluoroethylene (PTFE) + multiwalled carbon nanotubes (MWCNTs). Polytetrafluoroethylene is transparent to electromagnetic radiation, but after the addition of 10 wt% multiwalled carbon nanotubes, the composite demonstrates a more than 400-fold decrease in the electromagnetic radiation intensity when the radiation passes through a specimen with a thickness of ≈2 mm. It was found that the average radius of the free volume pores and the probability of annihilation of positrons in this area are determined by the electronic structure parameters of the polymer matrix only. The Fermi angle and the probability of positrons annihilation with free electrons are determined by the electronic structure parameters of MWCNTs only. Since the electronic structure of the cores and defects of the polymer matrix (at least outside the interphase) does not change, changes in these characteristics are mainly due to changes in the MWCNTs electronic structure. It was found that in a specimen with 10 wt% MWCNTs, the highest density of free electrons is observed, and the highest electron density is observed on defects. The average of free volume pore radius reaches its maximum value at 10 wt% MWCNTs in the composite.
Prevalence, Sociodemographic Correlates and Associated factors of Somatoform and Whiteley Disorders among Internally Displaced Persons in Ogoja displacement settlements, Nigeria: A Cross-sectional Study
Authors: Ugbe Ugbe Maurice-Joel , Esu Ekpereonne Babatunde , Onwusaka Obiageli Chiezey , Bisongedam Marvin Muji , Efut Joseph Ajah , Ekpo Ofem Irom 
Published: January 2022

Abstract
Experiences of displacement have been associated with the prevalence of various mental health disorders owing to certain factors. This study aimed to identify the prevalence, sociodemographic correlates, and other factors associated with Somatoform and Whiteley disorders among internally displaced adults in Ogoja displacement settlements, Nigeria. This was a cross-sectional study of 335 respondents. Somatoform and Whiteley disorders were assessed using the SOM-SCL and Whiteley-7 sections of the Common Mental Disorder Questionnaire while a semi-structured questionnaire was used to collect data on sociodemographic and displacement-related factors. Data were analyzed using descriptive statistics, Chi-square, and multivariable logistic regression. The prevalence of somatoform and Whiteley disorders was 59.1% and 84.8% respectively. Factors found to be significant in each bivariate Chi-square analysis were modeled for each mental disorder. The multivariate analysis revealed that being married (AOR=2.80; p=0.02) prolonged displacement (AOR=3.29; p=0.003), discrimination (AOR=2.25; p=0.01), disease outbreak (AOR=1.92; p=0.03), loss of loved ones (AOR=1.34; p=0.028), overcrowded households (AOR=2.30; p=0.008), and fear of reprisals (AOR=2.05; p=0.026) were significantly associated with somatoform disorder. Younger ages, low income (AOR=5.43; p=0.006), longer duration of displacement (AOR=8.43; p=0.020), separation from family (AOR=4.19; p=0.004), and loss of loved ones (AOR=3.57; p=0.006) were significantly associated with Whiteley problems. The findings suggest that the high prevalence of the studied outcomes are related to many demographic factors, life stressors and events. A synergetic effort by different bodies in creating and routinely arranging mental health interventions for this population is recommended.
Research on Energy Consumption Evaluation of Electric Vehicle Considering Air Conditioning Energy Consumption
Authors: Li Ning , Liu Yingshuai , Zhang Junzhi , Li Chao , Ji Yuan , Liu Weilong 
Published: January 2022

Abstract
This article discusses how to accurately evaluate the whole vehicle energy consumption under different refrigeration and heating working states of electric vehicles. Firstly, using the actual driving test data of electric vehicle, the weight coefficients of electric vehicle under refrigeration, heating and uncooled heating were obtained by algorithm. Then, the above weight coefficient was combined with the drum test results to obtain the annual comprehensive 100km energy consumption value of the vehicle, at the same time, the comprehensive energy consumption value of 100km of the vehicle under different comfort control modes of electric vehicle was analyzed. The related vehicle tests were carried out, the simulation and experimental results showed that the weight coefficient obtained by the least square method can better reflect the real energy consumption of the whole vehicle, the evaluation method of 100km energy consumption of electric vehicle proposed in this paper is a feasible evaluation method.
Geochemical Characterization of Shale Deposits Around Afikpo Area, Southeastern Nigeria
Authors: Okonkwo Stellarmaris , Okunlola Olugbenga 
Published: January 2022

Abstract
The mineralogical and geochemical composition of shale sourced from Mamu and Nkporo Formations, around Afikpo area in south-eastern Nigeria, were investigated to evaluate the source rock composition/provenance, infer paleo-redox conditions, sedimentary cycle, maturity and the intensity of source area weathering. Dominant clay mineral in both formations is kaolinite. Plots of Al2O3 vs. SiO2, TiO2 vs. Al2O3, Th/Sc*100 vs. Zr/Sc, La – Th – Sc and Cr/V vs. Y/Ni with observed light rare-earth elements (LREE) enrichment and negative Eu anomalies (Eu/Eu*: 0.04 – 0.08 for Nkporo and 0.06 – 0.08 for Mamu Formation samples) indicates largely felsic sources provenance, supported by presence of kaolinitic mineral. The redox-sensitive trace element values (Mo, U, and V) suggest a marginal marine (oxic) environment for Mamu Formation shale but marine (oxic to anoxic) setting for Nkporo Formation, this was supported by U/Th and Ni/Co values as their ratios suggest that the depositional basin experienced oxic to anoxic depositional conditions. The characteristic moderate HREE depletion pattern with low GdN/YbN ratios for the investigated Afikpo shale indicates non- monazite accumulation in the samples. The sediments are mature according to values of ICV, ratios of Th/Sc and Zr/Sc. Plots of CIA vs. SiO2, ICV vs. CIA with Al2O3-(CaO + Na2O)-K2O signpost an intense weathering in the source area. There is insignificant differences between the weathering and sediment maturity for the shale sediments of both formations from the same sedimentary basins, however, there exist disparity in their source rock/provenance and redox settings justifying the different formations.
Paragenesis and precipitation stages of Nb-Ta-oxide minerals in phosphorus-rich rare-element pegmatites (Buranga dike, Rwanda)
Authors: Araujo Fernando Prado , Hulsbosch Niels , Muchez Philippe 
Published: January 2022

Abstract
Nb-Ta-oxide minerals (NTO) are commonly associated with rare-element pegmatites where they are interpreted to precipitate at magmatic to magmatic-hydrothermal conditions. Although high-temperature experiments show that phosphorus and other fluxing elements (e.g., Li, B, F) can affect the saturation of NTO in pegmatitic systems, it is still uncertain how NTO saturation occurs in natural, flux-rich pegmatitic melts and whether crystallization occurs at multiple stages during magmatic or subsolidus conditions. The lithium-cesium-tantalum (LCT) family P-rich Buranga granitic pegmatite (western Rwanda) is used as a type locality to address this question. NTO mineralization in the Buranga dike occurs in two mineralogical units: in mineralogically complex phosphatic nodules, and in albitized parts. In the phosphatic nodules, Fe-Nb-Ta-rich rutile and columbite-group minerals (CGM) are observed, while in the albitized parts, only CGM is found. Fe-Nb-Ta-rich rutile precipitates at the magmatic stage along with early primary phosphates (i.e., F-rich montebrasite, wyllieite, and fluorapatite). Conversely, CGM mineralization occurs at the magmatic-hydrothermal stage in association with replacement phosphates like bertossaite, after primary minerals (i.e., rutile, wyllieite, rosemaryite, and trolleite) are destabilized due to crystal-melt-fluid interactions. NTO textures and chemical zoning show uneven evolution from core to rim and are related to localized alteration phenomena of the surrounding minerals. This indicates that local processes and element transfers are more important than dike-scale fractionation processes for NTO mineralization in P-rich granitic pegmatites. The restricted availability of Fe and Mn in the system, which is related to the competition between phosphate and oxide minerals, is identified as the main control on the CGM mineralization in the Buranga dike. CGM precipitation is only possible during the magmatic-hydrothermal stage when Fe and Mn are leached from the primary phosphates and remobilized to the Nb-Ta-bearing residual melt by the exsolved fluid.
Runoff forecasting model based on CEEMD and combination model: a case study in the Manasi River, China
Authors: Lian Lian 
Published: January 2022

Abstract
Accurate forecasting of runoff is necessary for water resources management. However, the runoff time series consists of complex nonlinear and non-stationary characteristics, which makes forecasting difficult. To contribute towards improved forecasting accuracy, a novel combination model based on complementary ensemble empirical mode decomposition (CEEMD) for runoff forecasting is proposed and applied in this paper. Firstly, the original runoff series is decomposed into a limited number of intrinsic mode functions (IMFs) and one residual based on CEEMD, which makes the runoff time series stationary. Then, approximate entropy is introduced to judge the complexity of each IMF and residual. According to the calculation results of approximate entropy, the high complexity components are predicted by Gaussian process regression (GPR), the medium complexity components are predicted by support vector machine (SVM), and the low complexity components are predicted by autoregressive integrated moving average model (ARIMA). The advantages of each forecasting model are used to forecast the appropriate components. In order to solve the problem that the forecasting performance of GPR and SVM is affected by their parameters, an improved fireworks algorithm (IFWA) is proposed to optimize the parameters of two models. Finally, the final forecasting result is obtained by adding the forecasted values of each component. The runoff data collected from the Manasi River, China is chosen as the research object. Compared with some state-of-the-art forecasting models, the comparison result curve between the forecasted value and actual value of runoff, the forecasting error, the histogram of the forecasting error distribution, the performance indicators and related statistical indicators show that the developed forecasting model has higher prediction accuracy and is able to reflect the change laws of runoff correctly.
Assessment of the groundwater quality by using multivariate approach and non-carcinogenic risk of uranium in the inhabitants of the Bastar district, Chhattisgarh, Central India
Authors: Singh Mayank , Sahu Pokhraj , Tapadia Kavita , Jhariya Dalchand 
Published: January 2022

Abstract
The elevated levels of uranium found in 17 states of India is alarming due to the radionuclide contamination in groundwater. Chronic ingestion can cause potential harm to humans and living things such as damage to kidneys, and cancer of the liver, lungs, and bones. The present study was undertaken to assess groundwater quality using a multivariate approach to the non-carcinogenic exposure of uranium by residents of the Bastar district, Chhattisgarh. The concentration of uranium in groundwater samples ranged from 0.50–26.4 μg/l in 70 samples, with 82% of samples being beyond the recommended limits by the International Commission on Radiological Protection. Hierarchical cluster analysis divided all sampling locations into 10 clusters explaining the similarity of geological conditions. Factor analysis extracted four principal components or factors with 70.20% cumulative variance from the entire data set. Chronic daily intake has been found above from the reference dose as 34.29, 42.86, and 51.43% for young children, children and adults. The results of hazard quotient analysis classified the degree of non-carcinogenic risk which was &gt;1 in 34.28, 45.71, and 41.43% for the samples from young children, children and adults, respectively. This study will generate baseline data and suggest the need for revision of water quality monitoring plans and preventive water management practices.
Effect and Mechanism of the Lenvatinib@H-MnO2-FA Drug Delivery System
in Targeting Intrahepatic Cholangiocarcinoma
Authors: Ning Zhouyu , Yang Lina , Yan Xia , Wang Dan , Hua Yongqiang , Shi Weidong , Lin Junhua , Meng Zhiqiang 
Published: January 2022

Background:
To investigate the effects of the Lenvatinib@H-MnO2-FA administration system on
the proliferation and apoptosis of Intrahepatic cholangiocarcinoma (ICC) and the underlying molecular mechanism.

Materials and Methods:
In this research, hollow MnO2 (H-MnO2) was synthesized via the modified Stöber
method, and H-MnO2 was modified with polyethylene glycol-bis (Amine) (NH2-PEG-NH2) and folic acid (FA)
to obtain H-MnO2-PEG-FA (H-MnO2-FA). Lenvatinib was coated in the hollow cavity of H-MnO2-PEG-FA to
further form a nanometre drug-carrying system (Lenvatinib@H-MnO2-PEG-FA). Lenvatinib@H-MnO2-FA
was characterized through transmission electron microscopy (TEM) and scanning electron microscopy (SEM).
Fourier transform infrared spectroscopy (FT-IR) was used to verify that Lenvatinib was loaded on nanoparticles.
Functionally, confocal laser scanning microscopy (CLSM), 2-(4-Amidinophenyl)-6-indolecarbamidine dihydrochloride
(DAPI) staining, and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay
were performed to determine the effect of Lenvatinib@H-MnO2-FA on the proliferation and apoptosis of ICC
cells (9810 cells). Finally, the protein levels of Raf-1MEK1/2-ERK1/2 signalling pathway components were detected
through Western blotting analysis.

Results:
We successfully synthesised a Lenvatinib@H-MnO2-PEG-FA administration system. The resulting
nanomaterials had excellent biological stability and improved targeting effects. Functionally, Lenvatinib@
H-MnO2-FA inhibited the proliferation of 9810 cells. The Bcl-2 protein level was significantly downregulated,
and the caspase-3 protein level was significantly upregulated, indicating that Lenvatinib@H-MnO2-
PEG- FA promoted the apoptosis of 9810 cells. Mechanistically, Lenvatinib@H-MnO2-FA increased the phosphorylation
levels of Raf, MEK1/2, and ERK1/2.

Conclusions:
H-MnO2-FA can more effectively deliver Lenvatinib to inhibit proliferation and promote apoptosis
in ICC, which could be the promising drug delivery nano-vehicles for delivery drugs.
The Advances in Bioactivities, Mechanisms of Action and Structural Optimizations of Matrine and its Derivatives
Authors: Lv Min , Xu Hui , Xu Jianwei 
Published: January 2022

Abstract:
Matrine, a tetracyclo-quinolizidine alkaloid, is isolated from the industrial crop plant Sophora flavescens. Due to a wide range of pharmacological and agricultural properties, the research on the phytochemistry, pharmacology, toxicology, and mechanisms of action of matrine and its derivatives has received much attention. On the other hand, to improve their biological activities, the study on structural optimizations and structure-activity relationships of matrine and its derivatives has also attached more and more importance. In this review article, the updates regarding the advances in bioactivities, mechanisms of action, structural modifications, and structure-activity relationships of matrine and its derivatives from 2017 to 2020 are presented. We hope that this review will provide a reference for the development and application of matrine and its derivatives as drugs or pesticides in the future.
Breviscapine Combined with BMSCs Reduces Aβ Deposition in Rat
with Alzheimer's Disease by Regulating Circular RNA ciRS-7
Authors: Huang Wei , Sun Fengqin , Zhang Yulin , Wu Xinran , Xu Xu , Zhu Chaodie 
Published: January 2022

Aims:
This study aimed to clarify that breviscapine combined with bone
marrow mesenchymal stem cells (BMSCs) treatment can reduce Aβ deposition in
Alzheimer's disease (AD) patients.

Background:
AD is a common degenerative disease of the central nervous system. Aβ
protein deposition in the cerebral cortex and hippocampus causes neuronal peroxidation
damage, synaptic dysfunction, neuroinflammation, and nerve cell apoptosis, and
ultimately leads to AD.

Objective:
To investigate whether breviscapine combined with BMSCs treatment can
reduce Aβ deposition in AD.

Metchods:
The AD rat model was successfully induced by Aβ1-42. The expression of
protein and mRNA was detected by western blot and reverse transcription-quantitative
PCR (RT-qPCR), respectively.

Results:
In AD rat brain tissue, the expression of circular RNA ciRS-7 (ciRS-7), ubiquitin
carboxyl-terminal hydrolase L1 (UCHL1), and NF-kappaB p65 was significantly
downregulated, and the expression of β-amyloid precursor protein (APP), β-site APPcleaving
enzyme 1 (BAEC1), and Aβ was upregulated. The expression of ciRS-7,
UCHL1, and p65 was significantly upregulated after breviscapine or BMSCs treatment,
and there was increased APP and BAEC1 degradation. Notably, breviscapine combined
with BMSCs treatment was more effective than either treatment alone. In SH-SY5Y
cells, overexpression of ciRS-7 reduced Aβ deposition by upregulating UCHL1 to
degrade APP and BAEC1, but these effects were reversed with inhibition of NF-kB
signaling. Finally, knockdown of ciRS-7 elevated Aβ, APP, and BAEC1 expression in
each group of rats compared with the control.

Conclusion:
Breviscapine combined with BMSCs treatment can reduce Aβ deposition in
AD rats and promote the degradation of APP and BAEC1 by activating NF-kB to
promote UCHL1 expression.
PERANCANGAN APLIKASI PEMANTAUAN PENJUALAN DENGAN KEAMANAN SINKRONISASI DATA DENGAN WEB SERVICE PADA CV. SURYA MULTI KARYA
Authors: Sandy Mardian Puli , Tony Tony 
Published: January 2022

Aplikasi yang dirancang adalah aplikasi pemantauna penjualan pada CV. Surya Multi Karya, yaitu aplikasi yang berbasisi aplikasi desktop dan website. Pada saat ini CV. Surya Multi Karya memiliki satu cabang yang tempatnya berjauhan dengan toko pusat. Aplikasi desktop akan digunakan untuk melakukan segala transaksi yang terjadi pada CV. Surya Multi Karya yang berupa transaksi penjualan dan peng-input-an data barang yang masuk dan keluar, sedangkan website bertujuan untuk menunjukan report dari hasil penjualan dan stok barang pada CV. Surya Multi Karya. Pada aplikasi ini menggunakan web service yang di dalam terdapat WCF yang dimana berguna untuk mensinkronisasikan data pada database agar dapat digunakan oleh CV. Surya Multi Karya.
Program Stimulasi Kesiapan Anak Masuk Sekolah Dasar Bagi Orang Tua di Kelurahan Jetaksari Kecamatan Sayung Kabupaten Demak
Authors: Agustina Setiowati Erni , Handayani Agustin , Supradewi Ratna 
Published: January 2022

Program pendampingan ini bertujuan untuk meningkatkan pengetahuan orang tua dalam memberikan stimulasi yang tepat agar anak usia 6-7 tahun siap memasuki sekolah dasar. Pada saat berada di taman kanak-kanak (TK), guru TK memberikan berbagai stimulasi diantaranya keterampilan motorik halus dan kasar, kemampuan mengenali objek dan kegunaanya, bersosialisasi, mengenal moral sesuai usianya serta menghitung benda. Disamping itu, orang tua memberikan stimulasi yang mengarah pada aktivitas yang ditujukan agar anak cepat beradaptasi dengan tugas akademik di sekolah dasar. Akan tetapi, tidak jarang orang tua kemudian lebih menekankan anak lancar menulis, membaca, dan berhitung. Padahal dalam kesiapan masuk sekolah juga harus memperhatikan kesiapan fisik dan motorik, emosi, sosial, bahasa, dan ketertarikan untuk belajar. Sebanyak 29 orang tua anak TK (RA) Al Khusaini mengikuti kegiatan ini dan untuk mengetahui kesiapan anak masuk sekolah dilakukan Tes Kesiapan Sekolah menggunakan NST (Nijmeegse Schoolbekwaamheids Test) terhadap 15 anak usia 5,0 sampai 5,9 tahun dari total 29 anak TK B. Hasil tes NST menunjukkan ada 7 anak berada pada kategori siap dan sisanya belum siap, selain itu orang tua diberi angket pengetahuan mengenai kesiapan anak masuk sekolah. Data menunjukkan bahwa sebagian besar orang tua memandang melatih kemampuan membaca, menulis dan berhitung yang paling penting sehingga lebih menekankan aspek ini dalam menstimulasi. Hasil pengabdian masyarakat ini diketahui bahwa orang tua setelah kegiatan pendampingan mengetahui aspek-aspek kesiapan anak masuk sekolah dan cara-cara menstimulasinya yang akan mendukung keberhasilan anak belajar di SD.
Novel Heuristic Approach for Solving Multi-objective Scheduling Problems
Authors: Amin Begard A. , Ramadan Ayad M. 
Published: January 2022

In this paper, we studied the scheduling of jobs on a single machine. Each of n jobs is to be processed without interruption and becomes available for processing at time zero. The objective is to find a processing order of the jobs, minimizing the sum of maximum earliness and maximum tardiness. This problem is to minimize the earliness and tardiness values, so this model is equivalent to the just-in-time production system. Our lower bound depended on the decomposition of the problem into two subprograms. We presented a novel heuristic approach to find a near-optimal solution for the problem. This approach depends on finding efficient solutions for two problems. The first problem is minimizing total completion time and maximum tardiness. The second is minimizing total completion time and maximum earliness. We used these efficient solutions to find a near-optimal solution for another problem which is a sum of maximum earliness and maximum tardiness. This means we eliminate the total completion time from the two problems. The algorithm was tested on a set of problems of different n. Computational results demonstrate the efficiency of the proposed method.
EU Aid for Fighting Corruption in the Czech Republic and Slovakia: Where Did It Go Wrong?
Authors: De Ridder Eline 
Published: January 2022

During the Eastern enlargement process of the European Union (EU), the Central and Eastern European Countries (CEECs) were supported by the Union in terms of combating corruption issues. This was seen as a key step in their transformation towards liberal democracy and eventual accession to the EU. This article questions the extent of influence which the EU has had in terms of dealing with problems of corruption in the Czech Republic and Slovakia, both during and after their accession to the Union. It is noted that during the accession process the EU utilised a number of instruments to support accession states, such as the Czech Republic and Slovakia, fight corruption. Regardless of these incentives, the corruption records of both countries improved little by the time they acceded to the EU in 2004 and continues to be problematic in the post-accession era. It is suggested in this article that several dynamics, such as the absence of a clear and consistent policy from the EU and the importance of domestic politics in the acceding countries, help to explain why the fight against corruption in these two central European states has been and continues to be so weak.