bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mapping by VESGEN of Leaf Venation Patterning in Arabidopsis thaliana with Bioinformatic Dimensions of Gene Expression
Authors: Parsons-Wingerter Patricia , Vickerman Mary B. , Paul Anna-Lisa , Ferl Robert J. 
Published: January 2022

ABSTRACT
The leaf venation of angiosperms is key to their terrestirial dominance. These higher land plants include maple, corn, and ISS model organism Arabidopsis thaliana. The venation-dependent photosynthetic capacity of angiosperm leaves is largely responsible for terrestrial production of glucose and atmospheric oxygen, and may be fundamentally important to long-term space colonization. Leaf studies in orbit, where human-tended experiments are limited, can be enhanced by quantifying complex venation patterning. VESsel GENeration Analysis (VESGEN), a beta-level NASA software that analyzes vertebrate and human vascular branching for biomedical applications, is therefore being modified to map the branching venation patterns of dicot angiosperm leaves. By physiological branching rules, VESGEN decomposes a continuously connected vascular tree into its structural (dendritic) branching and reticulate (networked) capillary components.
For an arabidopsis juvenile leaf flown on NASA Space Shuttle Mission (STS)-130, the venation patterning of larger structural vessel orders 1°-2° remained relatively constant compared to normal gravity (by vessel number density Nv
, 1.24E-5/micron2, and 1.29E-5/micron2, respectively). However, as a measure of increased venation maturity, Nv
of smaller reticulate orders ≥ 3° increased considerably from 7.7E-6/micron2 in ground control to 1.74E-5/micron2 in the STS-130 leaf. Vascular geometric complexity is another feature of plant development that is governed in part by changes in gene expression patterns responding to environmental influence. We therefore propose that the mapping of leaf venation patterns by VESGEN can provide additional insight into plant responses to the spaceflight environment.
Detection of DNA Microsatellites Using Multiplex Polymerase Chain Reaction Aboard the International Space Station
Authors: Chen Sophia , Hatch John , Luck Ashley , Nichols Nicole M. , Gleason Emily J. , Martin Kathryn , Foley Kevin D. , Scott Copeland D. , Kraves Sebastian , Saavedra Ezequiel Alvarez 
Published: January 2022

Abstract
As human exploration extends further into deep space, it is critical to understand the cellular impacts of spaceflight in order to ensure the safety of future astronauts. Extended exposure to cosmic radiation and microgravity has been shown to cause genetic damage and impair cellular DNA repair mechanisms, which together can lead to genomic instability. In particular, microsatellite instability (MSI), in which dysfunction in DNA mismatch repair (MMR) causes alterations in tandemly repeated “microsatellite” sequences, is a manifestation of genomic instability that has been associated with certain cancers. In this study, we establish the feasibility of an on-orbit multiplex polymerase chain reaction (PCR)-based assay to detect mutations in cancer-related microsatellites. Multiplex PCR was used to amplify five quasimonomorphic microsatellites in space and on Earth from both wild-type and MMR-deficient human cell lines. These data provide proof of concept of simultaneous amplification of multiple DNA sequences in space, expanding in-flight research and health-monitoring capabilities.
Entomopathogenic fungus, Metarhizium anisopliae, anchored onto MCM-41 silica nanomaterial: A novel and effective insecticide against potato tuber moth in stored potatoes
Authors: Khorrami F. , Soleymanzade A. , Batmani H. , Ghosta Y. 
Published: January 2022

Summary

Phthorimaea operculella (PTM) is an economically significant invasive potato insect pest in tropical and sub-tropical regions. Due to many problems concerning chemical insecticides, biocontrol agents such as entomopathogenic fungi have attracted researchers’ interest regarding their application as a part of integrated potato tuber moth management strategies in several countries. Hence, in the present study, we examined the lethal effects of entomopathogenic fungus, Metarhizium anisopliae (used as pure culture (PEF) or formulated with MCM-41 silica nanomaterial (MCM-41@fungus)) on eggs and neonate larvae of PTM. The MCM-41was completely characterized by Fourier transform infrared (FT-IR), Scanning Electron Microscopy (SEM), Energy Dispersive X-ray (EDS), X-ray diffraction (XRD), and Thermogravimetric analysis (TGA) techniques. The morphology of MCM-41@fungus was evaluated by scanning electron microscope (SEM). The morphology of the mesoporous structure was exhibited to be homogeneous, regular, and spherical. LC50 values of PEF and MCM-41@fungus were estimated to be 1.7×107 and 2×105 conidia/ml for eggs and 1.8×106 and 1.5×104 conidia/ml for neonate larvae, respectively. Hence, bioassays demonstrated that MCM-41@fungus was more toxic than the pure culture at egg and neonate larval stages of the pest. The results exhibited that pure M. anisopliae and its nano-formulation could play key roles as biopesticides in management programmes of P. operculella.
A Review of Results from Clinical Trials Based on Co-Variants of the R-CHOP Regimen in Untreated Patients with Diffuse Large B-cell Lymphoma
Authors: Popova Vanya S. 
Published: January 2022

Summary
Since 2000, new drugs for treating lymphoproliferative diseases have been introduced in haematology, and their initial indications have been gradually expanded. Some of the so-called „target molecules“ have shown good efficacy when treating some malignant non-Hodgkin lymphomas. The possibility of achieving therapeutic disease control in some indolent non-Hodgkin lymphomas using drugs with a different mechanism of action from that of cytostatics has logically raised the question of a change in therapeutic management in other lymphoproliferative diseases. Since 2010, clinical trials have been initiated with untreated patients with aggressive non-Hodgkin‘s lymphoma - diffuse large B-cell lymphoma as the primary target. The key aim of most clinical trials has been to compare the efficacy of the so-called „gold standard“ - rituximab, cyclophosphamide, doxorubicin, oncovin, prednisolone (R- CHOP) versus its derivatives. The review discusses the results of completed clinical trials published on the Internet. These trials covered covariants of the R-CHOP regimen used as first-line treatment of patients with diffuse large B-cell lymphoma. The review also includes drugs registered in Bulgaria for the last ten years but with a different clinical indication at present. The results of five clinical trials in which obinotuzumab, venetoclax, lenalidomide, bortezomib, and ibrutinib were used are presented.
The Role of Uterine Infection in Pregnancy Outcome: A Case Report
Authors: Bodurska Tatyana T. , Konova Emiliana I. , Pachkova Svetlana , Yordanov Angel D. 
Published: January 2022

Summary
It was believed in the past that only the lower genital tract is inhabited by microorganisms, and the cervix was considered as a perfect barrier against the ascension of microbes. Nowadays, many studies using new sequencing technologies examining microbiomes with low biomass show that the microorganisms are gradually changing from the lower to the upper genital tract with decreasing bacterial abundance and increasing bacterial diversity. It is well documented that the endometrium is a non-sterile area, and in healthy women, the Lactobacillus spp. is the dominant flora. Lactobacillus - as a dominant endometrial microbiome, has a crucial role in implantation, early pregnancy development. It is also essential for a good pregnancy outcome. Non-Lactobacillus-dominant microbiome is associated with poor reproductive outcomes (recurrent implantation failure, recurrent miscarriages, outgoing pregnancy). This association is evidence of its significance for reproductive health.
We present a case of unsuccessful first pregnancy with concurrent bacterial endometrial infection. A definitive antibiotic treatment resulted in a successful full-term second pregnancy. We present the influence of pathogenic microorganisms on uterine function and pregnancy development, current possibilities for diagnosis and treatment.
Macroprudential Transparency and Price Stability in Emerging and Developing Countries
Authors: Trabelsi Emna 
Published: January 2022

Abstract
One of the focuses of recent literature has been the macroeconomic effects of macroprudential policy instruments. The innovation of this paper is that it studies the effects of transparent macro-prudential policies on price stability. The results presented herein provide the first empirical evidence that macroprudential transparency can aid to achieve stable inflation in emerging and developing countries. The effect is necessarily transmitted through reduced occurrence of banking crises. We also record a particular advantage of macroprudential transparency for non-inflation targeting countries. Overall, the results are robust to the use of two proxies of price stability.
Liquidity Dynamics of Banks in Emerging Market Economies
Authors: Mashamba Tafirei 
Published: January 2022

Abstract
This study examines the liquidity dynamics of banks in emerging market economies. Using annual data of 91 commercial banks from 11 countries, the study established that banks in emerging markets have target liquidity ratios they pursue and partially adjust due to market frictions. Overall, risk aversion and prudence play a significant role in explaining the liquidity dynamics by banks in emerging market economies.
Identification of Information System Audit Quality Factors
Authors: Alagić Amra , Turulja Lejla , Bajgorić Nijaz 
Published: January 2022

Abstract
The primary purpose of this work is to provide an overview and comparative analysis of various Information System Audit Quality measures, as well as to test the validity of the chosen measurement scale empirically. In this regard, a thorough literature study was undertaken, followed by primary empirical research, and the reliability and validity of the measurement scale were tested. Based on the identified papers, a questionnaire was created and evaluated by a panel of experts. Following that, data was collected from respondents who were either managers inside the organizational unit responsible for information technology or those designated as adequate by the heads of IT departments.
Origin and the Outline of Florian Znaniecki’s Psychology of Culture
Authors: Chojniak Arleta 
Published: January 2022

Summary
The aim of this paper is to present the cultural psychology project formulated by Florian Znaniecki. In the first part of the article, the authoress reconstructs the origin of this concept by reviewing the scholar’s early philosophical writings. In the second and third part of this paper, the authoress focuses on presenting the basic categories of Znaniecki’s theory such as culture, culturalism and cultural action and highlights the role of cultural psychology in his scientific system.
Depression in Children and Adolescents as a Result of Personal and Social Development Problems
Authors: Ćwikliński Andrzej 
Published: January 2022

SummaryThe article deals with the issue of depression in children and adolescents as a shortcut to problems of individual and social development. It presents the concept of depression and its typologies, showing depression as a disease increasingly common among children and adolescents. The biological and social causes of depression among young adolescents are indicated and other sources of depressive behaviors are also described. A particular role of the family in overcoming the symptoms of depression is highlighted.
Using of Didactic Measuring Instruments as an Example of Pedagogical Creativity in Selected Graduation Theses
Authors: Derenowski Marek 
Published: January 2022

Summary
Evaluating students’ work has always been a challenging undertaking. The objectivity and reliability of instruments may sometimes be doubtful. Therefore, the aim of the study described in the paper was to analyze possible innovative behaviors/activities among MA students/teachers/researchers in the field of assessment described in their MA thesis. It is intriguing to find out whether future and present educators take the effort (and risk) of introducing some improvements in this crucial educational field.
Personal Internal Space in Educational Leadership
Authors: Ptak Małgorzata M. , Śmiałek Mirosław J. 
Published: January 2022

Summary
The space between the subjective and objective fills a person’s identity. It is knowledge about oneself, about the difference between oneself and others / strangers, about one’s own actions, their effects and consequences. It is likewise knowledge of one’s own uniqueness, of the consequences of one’s own actions that define the limits of one’s own identity.
Identity is a personal internal space, built on the basis of empathy, autonomy, distance, assertiveness, activity, and tolerance. Identity is different dimensions of individuality, uniqueness and separateness, compatibility of thoughts-feelings-actions, self-esteem and intentionality important for interpersonal and social conflicts. It serves to build and consolidate an image of oneself and knowledge about oneself. Identity allows a person to self-reflect, receive insight, evaluate, make changes, and strengthens the image of his/her person, offering a sense of separateness and being yourself.
Replacing urban identity: the disappearance of Sha’biya Al Safa Neighborhood
Authors: Donner Luca , Sorcinelli Francesca 
Published: January 2022

The meaning of identity of a place is manifested in its genius loci, or rather in the hidden spirit of the place itself. The immanent value of the built environment represents its physical and materic sedimentation, as well as the collective memory testifies to the emotional stratification of the space itself. The spatial component involves not only the sphere of urban form and public spaces, but also the private dimension of domesticity. It is a process of accumulation of the historical memory of a place, through fragments of shared community life as well as of family and domestic identities. In this sense, the theme of loss of urban historical memory in newly developed contexts, in cities such as Dubai for example, appears relevant. Furthermore, how in such areas the built environment is suddenly altered by the dynamics of real estate.
This contribution documents, also by means of photography, the case of the disappearance of Sha’biya Al Safa Neighborhood (also known as Sha’biya Al Shorta). Neighborhood built to house the low-income local population, as part of the social housing program wanted by the late Sheikh Zayed bin Sultan Al Nahyan since the end of the 1960s. These photos, taken in September 2018, document the state of the neighborhood shortly before its demolition, when its inhabitants had already abandoned this place. Instead, the pictures taken in February 2021 describe the current state of the area: an infrastructured tabula rasa ready for real estatedevelopment.
The images narrate the loss of daily living in the neighborhood. They speak of a community, which has now disappeared, characterized by a vibrant everyday life with cultural values rooted in the place and tradition. It is a visual testimony that identifies the urban peculiarities of the neighborhood in its morphological and typological dimension, as well as reveals the traces of the family life of its inhabitants. This case documents, once again, how urban transformations based on demolition and new construction inevitably lead to a zeroing of the original social identity and of the collective memory connected to the place itself.
From intimacy to urban landscape: images of the transformations of the Rainha Dona Leonor social housing.
Authors: Roberti Ana Clara , Santos Helena , Brandão Daniel 
Published: January 2022

The present communication proposes an imagery study on the transformations of the social housing Rainha Dona Leonor, in Porto, rehabilitated between 2017 and 2019. Through an immersive ethnographic work, it was possible to closely follow the radical changes that took place, from the demolition of the five housing blocks to the construction of a single block.
In short, our methodology was guided by the following phases: 1) a series of exploratory visits to analyze the spatial morphology, the living conditions, the forms of occupation of shared spaces and the atmosphere of the neighborhood (receptivity, sense of security, accesses, flow of non-residents); 2) further research into the history, context, and contemporary setting of the site; and 3) the close observation and follow up of two families from old residents.
The idea of using photography as a resource for data collection and representation of the situation was due to its ability to convey the impact of the changes on the landscape, on the lives of the residents, and on their narratives before the demolition of their homes and after moving to their new homes. We registered details inside their old homes (their old lives), before being packed up, or discarded in the move to the new apartments. Furthermore, photography was taken as a tangible reminiscence for these people, remnant of their past life.
A Walk through Urban Decay: al-Hattaba Is Worth Saving!
Authors: Khalf Yara A. , El Antably Ahmed , Abdelwahab Mona A. 
Published: January 2022

Beyond the glamour of Cairo history lies a different side of the city that unravels the unique beauty of urban decay. Al-Hattaba, a UNESCO heritage area, is caught in between these narrations of beauty and decay; the beautiful home whose inhabitants want to keep and grow, and the formally enlisted dangerous informal space subject to eviction and demolition.
Al-Hattaba embraces the beauty of its rich and diverse history, growing through time. It beholds moments of prosperity, failure, change, beauty, and loss.
Urban decay photography is used to interpret al-Hattaba’s controversy and explore the bonds between time and memory. We take the reader through a visual journey in al-Hattaba.
It constitutes a photo-sequence that considers al-Hattaba in reflection of its background context, the Citadel of Saladin; historic and residential buildings, some abandoned and attempts of local renovation. This urban setting reflects a rich visual diversity that witnessed its changes through time. We argue that the essence of al-Hattaba’s beauty is in its urban decay. It is a space that will never fail to amaze its visitors with its hidden beauty.
MOTIVASI DAN PERSEPSI WISATAWAN NUSANTARA BERKUNJUNG KE JATILUWIH, TABANAN
Authors: Ayu Diah Utari Ni Made , Wijaya NMS. , Sudana I Putu 
Published: January 2022

This research is done by four national tourist motivations namely physical motivation, culture motivation, social motivation, and fantasy motivation. Perception of domestic tourists is assessed from the tourism component, namely attraction, accesibility, amenities, ancilary services. This research has a purpose 1) to determine the motivation of Indonesian tourists visiting Jatiluwih tourist attraction, Tabanan regency. 2) to find out the perception of Indonesian tourists about the main components in tourism (4A) in the tourist attraction of Jatiluwih, Tabanan regency. This research uses purposive sampling method with the method of taking informants is accidental sampling and distributing questionnaires to 125 respondents of domestic tourists. The data collection tehniques used were observatio, interview, questionnaires, literature study, documentary study and the data analysis tehniques were descriptive qualitative and quantitative descriptive. The results of this study indicate that the highest motivation for domestic tourists to visit Jatiluwih tourist attraction is to enjoy the natural atmosphere and terraced rice fields, Jatiluwih ia a World Cultural Heritage, to interact with local people or farmers in Jatiluwih, and to seek new experiences. The perception of tourists towards the main components in tourism in the overall research is good. However, tourists feel that they are lacking in ancilary service on the indicator of the availability of ATM because these facilities are inadequate.
KOMUNIKASI EFEKTIF: AKTUALISASI KOMPETENSI SOSIAL GURU DALAM PERSPEKTIF
Authors: Mutiara Elvian , Zulvi Eva , Masrofah Shella , Husna Difa Ul 
Published: January 2022

AbstractSocial competence is the competencies that must be possessed by teachers or educators. The existence of investigating this social competence aims to reveal again about effective communication carried out by teachers with students or the community as a form of actualization of teacher competencies in an Islamic perspective. The method used in this research is in the form of qualitative analysis with a library research approach or library method. Social competence can be interpreted as a teacher's performance in speaking and communicating with students, fellow teachers, and the surrounding community in an effective and interactive manner. A teacher must have good social competence in carrying out their duties and roles. Without good communication skills, of course, the implementation of the education process and daily life will not run effectively and not as expected. Teacher social competence is divided into two, namely: teachers in the school environment and teachers in the community. If a teacher can develop their social competence, it will be easier to carry out their duties and responsibilities. Effective communication will be created by a teacher who has good social competence.Keywords: communication; social competence; Islamic perspective. AbstrakKompetensi sosial adalah salah satu kompetensi yang harus dimiliki oleh seorang guru atau pendidik. Adanya penelitian mengenai kompetensi sosial ini bertujuan untuk mengungkap kembali mengenai komunikasi efektif yang dilakukan guru dengan peserta didik ataupun masyarakat sebagai bentuk aktualisasi kompetensi guru dalam perspektif islam. Metode yang digunakan dalam penelitian ini yakni berupa analisi kualitatif dengan pendekatan library research atau metode kepustakaan. Kompetensi sosial dapat diartikan sebagai suatu kinerja guru dalam bercakap, dan berkomunikasi dengan para peserta didik, sesama pendidik, maupun dengan masyarakat sekitar secara efektif dan interaktif. Seorang guru harus memiliki kompetensi sosial yang baik dalam menjalankan tugas dan perannya. Tanpa adanya kemampuan komunikasi yang mumpuni, tentu pelaksanaan proses pendidikan dan berkehidupan sehari-hari tidak akan berjalan efektif dan tidak sesuai dengan yang diharapkan. Kompetensi sosial guru dibagi menjadi dua, antara lain: guru dalam lingkungan sekolah dan guru dalam bermasyarakat. Jika seorang guru dapat mengembangkan kompetensi sosialnya, maka akan lebih mudah dalam menjalankan tugas dan tanggung jawab. Komunikasi yang efektif akan tercipta dari seorang guru yang memiliki kompetensi sosial yang baik.Kata kunci: komunikasi; kompetensi sosial; prespektif islam.
المدخل التواصلي في تعليم اللغة العربية في الفصل الثامن في مدرسة مرضية إسلامية بانيابونجان
Authors: Pane Akhir , Nasution Ulpah Mawaddah 
Published: January 2022

AbstrakPembelajaran Bahasa Arab butuh sebuah pendekatan, khususnya pendekatan komunikatif. Masalah utama penelitian ini : siswa – siswa merasa kedulitan dalam berkomunikasi dalam bahasa arab, dan dalam pembelajaran belum dilaksanakan secara komunikatif. Tujuan penelitian ini untuk mengetahui kesulitan siswa – siswa berkomunikasi dengan bahasa arab dan mengetahui pembelajaran bahasa arab belum dilaksanakan secara komunikatif di kelas. Jenis penelitian ini kualitatif menggunakan data data lapangan dengan data deskriptif dalam bentuk penjelasan tertulis dan lisan. Alat pengumpul data menggunakan observasi, wawancara, analisis data menggunakan triangulasi untuk mengambil validitasnya. Hasil penelitian ini adalah berdasarkan observasi penulis diantara 13 poin – poin kesesuian pendekatan komunikatif 8 poin sudah diterapkan guru dan belum menerapkan 3 poin tersebut. Berdasarkan hasil observasi peneliti terhadap siswa diantara 13 poin – poin pendekatan komunikatif adalah 27, 85٪. Kata Kunci : Pendekatan Komunikatif, Pembelajaran Bahasa Arab