bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE BENEFITS OF GENERATION IDENTITY OVER AGE IDENTITY IN OLDER ADULTS: THE MEDIATING ROLE OF NOSTALGIA
Authors: Chang Yuanqing , Lu Jiehua , Zhang Xin 
Published: January 2025

Abstract

Background and Objectives
As individuals age, they develop two types of self-identification: age identity and generation identity. Previous research suggests generation identity is more beneficial in promoting well-being of older adults. However, the underlying mechanisms and the generalizability in the Chinese cultural context remain underexplored.

Research Design and Methods
This study employed a randomized single-factor between-subjects design with 160 community-dwelling Chinese older adults (M = 67.61 years, SD = 5.63 years; 31.88% men). Participants were randomly assigned to focus on similarities or differences with peers (age identity salience condition) or contemporaries (generation identity salience condition), followed by assessments of nostalgia and subjective well-being including life satisfaction, loneliness, meaning in life, and awareness of age-related changes.

Results
Word frequency based on lexicon text analysis revealed that participants in generation identity salience condition mentioned more era-specific events. The Biterm Topic Model (BTM) identified two themes: “Hardship of the Past vs. Present Happiness” and “Present Happy Life” in both groups. However, the generation group had a higher proportion of the first theme (56.25% vs. 42.5%). Independent T-tests indicated significant group differences in nostalgia and subjective well-being (p &lt;.05). Structural equation modeling revealed nostalgia could function as a significant mediator between identity salience condition and subjective well-being (β =.092, 95% CI = [0.000, 0.184]).

Discussion and Implications
The findings suggest that emphasizing generation identity can significantly enhance older individuals’ life satisfaction, meaning in life, and awareness of age-related gains, offering empirical support for strategies aimed at promoting active and successful aging.
THE CONNECTION BETWEEN SEROTONIN SIGNALING, AGING, AND IMMUNITY WHEN OBSERVED FROM C. ELEGANS AND HUMAN STUDIES
Authors: Kebbede Liyat , Weathers Brandy , Nair Tripti 
Published: January 2025

Abstract
As humans age, various environmental threats impact healthspan. Therefore maintaining an intact immune system is vital. Efficiency of human immune response can decline over time leading to complications with age-related diseases. Homeostatic mechanisms are in place to combat threats to the immune system. Serotonin, a neurotransmitter that critically regulates functions in inflammation and immune response, begins to lack functionality with aging. Signaling dysfunction in neurotransmitters can lead to complications in immune response and negatively impact healthspan. Using C. elegans, the connection between immune response and serotonin signaling can be investigated, as this model organism shares homology with the innate human immune system. The Curran lab designed a mutation in the homeostatic pathway resulting in low serotonin signaling. Consequently, impairment to pathogen sensing occurs. C. elegans rely upon the innate immune system to avoid and survive exposure to harmful bacteria. Their transparent nature and 30 day lifespan, allows for visualization of protein signaling and genetic tracing across the life. With a mutation in SKN-1, it has been observed that they become unaware of the dangers of a lethal pathogen, Pseudomonas aeruginosa (PA14), and are even apathetic towards its threat. The serotonin mutant animals remain on PA14 significantly longer than wild type (WT) animals. This study covers therapeutic interventions with serotonin administration and depletion to observe the neurotransmitters necessity in human clinical trials and C.elegans laboratory studies conducted in the Curran lab. Understanding how serotonin signaling impairs the behaviors of C. elegans underscores its importance in maintaining efficient immune response in humans.
THE DIGITAL DIVIDE AMONG CHINESE OLDER ADULTS: INTERNET USAGE AND EHEALTH LITERACY
Authors: Zhang Jiaan 
Published: January 2025

Abstract
In recent years, particularly due to the COVID-19 pandemic, digital dependency has grown significantly in China, exacerbating the digital divide as a pressing social issue. This study examines Internet usage and eHealth literacy among Chinese older adults aged 60 and above compared to their younger counterparts, using data from the newly available 2021 China General Social Survey. Internet usage was assessed by asking respondents whether they currently use the Internet. eHealth literacy was measured using the 8-item eHealth Literacy Scale, with each item scored on a 5-point Likert scale. Age groups were compared using chi-square tests and t-tests. Correlates of Internet usage and eHealth literacy were analyzed with logistic regression and OLS regression models, respectively. The results indicate that older adults significantly lag in Internet usage, with only 35.25% of those aged 60 and above using the Internet, compared to 89.09% of the under-60 group. Additionally, the younger group demonstrated significantly higher eHealth literacy scores. Regression analyses further revealed that the negative association between older age and Internet usage is more pronounced among rural residents, and that older age is more strongly associated with lower eHealth literacy scores in both women and rural residents, controlling for sociodemographic and socioeconomic status, social support, and health status. This study provides the most recent evidence of significant disparities between older adults and other age groups in China regarding Internet usage and eHealth literacy. It underscores the need for policies and programs focused on bridging the digital divide among older adults.
THE EFFECTS OF HEALTH COACHING ON PATIENT ACTIVATION AND WELL-BEING OF COMMUNITY-DWELLING OLDER ADULTS
Authors: Chung Edwin Ka Hung , Yeung Dannii Y , Chen Frank Youhua 
Published: January 2025

Abstract
Health coaching appears as a promising intervention to initiate behavioural change and improve health outcomes for outpatients (Krok-Schoen et al., 2017; Sharma et al., 2016). However, its effectiveness in improving self-management of chronic diseases were mainly examined in young and middle-aged adults with specific chronic diseases (Lin et al., 2021; Tülüce & Kutlutürkan, 2018). Whether health coaching is still effective in community-dwelling older adults, particular those with lower education and multiple chronic diseases, remains uncertain. This study thereby aims to examine the effects of a health coaching intervention in a sample of 194 older Hong Kong Chinese adults (Mage = 79.1, SD = 6.90, range = 62–95). Depending on their health needs, participants received 12 – 18-week home-based health coaching intervention during July 2022 – July 2024. Their patient activation, physical activity, nutrition behaviours, loneliness, and depression were measured before and immediately after the intervention. Repeated measures ANCOVAs showed that participation in the health coaching intervention significantly increased patient activation and nutrition-related health behaviours, and reduced loneliness and depression. Theses results remained significant even after controlling for age, sex, education, living arrangement, receipt of community centre and home care services, numbers of chronic diseases, polypharmacy, and frequency of intervention sessions. The findings of this study thus revealed beneficial effects of health coaching in enhancing older adults’ competence in managing their health, engagement in health behaviours, and psychological well-being. Policymakers and health-related professionals should implement health coaching in the primary healthcare system to maintain older adults’ well-being and promote ageing-in-place.
THE EVOLUTION OF FILIAL PIETY TO INTERGENERATIONAL SUPPORT IN TAIWAN
Authors: Lin Yunann , Weng Hui-Ching , Chih-Liang Wang 
Published: January 2025

Abstract

Objective
The practice of filial piety concept may vary with sociocultural transformation under aging impact. It’s crucial to interpret how filial behaviors affect parent–child interaction. Thereby, this study aimed to explore associations between filial piety and intergenerational support in Taiwan.

Methods
This longitudinal study analyzed data collected from the 2016 Taiwan Social Change Survey, consisting of demographics, self-rated health, sibling number, children number, coresident with parents or children, reciprocal filial piety (RFP), authoritarian filial piety (AFP), financial, household, and emotional support. Participants were categorized into three cohorts: the traditional generation (born before 1945), the baby boomer generation (1946-1964), and Generation X (1965-1980). ANOVA and multilevel regression were adopted to analysis intergenerational associations. Findings: AFP present significant decrease in the baby boomer (2.55 vs 2.9, p&lt; 0.001) and generation X (2.4 vs 2.9, p&lt; 0.001) when comparing with the traditional generation; while RFP show no difference among three cohorts. After adjusting gender, education, marriage, self-rated health, income, sibling number, and coresident with parents, RFP of generation X was positively associated with household (p=0.05) and emotional support (p&lt; 0.001) to parents. Moreover, AFP of baby boomer generation was marginal associated with financial (p=0.053) and household (p=0.058) support to parents.

Conclusion
The diminish of AFP embodied the trend of mutual affection and equality in the parent–child relationship. The mediation effect of RFP in generation X was practiced in household and emotional support; while the mediation effect of AFP in baby boomer generation was practiced in financial and household support.
THE IMPACT OF DIETARY PROTEIN RESTRICTION ON WHITE ADIPOSE TISSUE FUNCTION DURING AGING
Authors: Young Khristina , Easter Molly , Vaddi Prerana , Donkor Michael , Wong Meghan , Hill Cristal 
Published: January 2025

Abstract
White adipose tissue (WAT) regulates metabolic health, lipid storage and energy mobilization, yet these functions decline during aging and aging with obesity. Studies show that interventions such as dietary protein restriction (DPR) can improve metabolism, benefit overall health, and extend lifespan. Hence, the unique impact of DPR on the physiological function of adipose tissue represents a plausible target to support general health. Data from our lab and others show that DPR induces browning in WAT through thermoregulatory genes. This modification within the WAT produces beige adipocytes by marked increases in UCP1 (Uncoupling protein 1) gene expression and other related genes, such as the coregulator PR-domain containing 16 (PRDM16). Specifically, PRDM16 regulates adipogenic differentiation, thus playing a key role in regulating the function of adipose tissue. Our goal is to investigate if browning of WAT via Prdm16 is essential to improve metabolic health during DPR, and if DPR-induced improvements in metabolic health are sex dependent. Here, 3-months of age, male and female normal-control littermates and Prdm16 KO mice were fed either a normal protein (20%) or a low-protein (5%) diet for 7 months. Collectively, these data suggest that Prdm16 contributes to dependent and independent metabolic endpoints on body weight, glucose and lipid homeostasis, and adipokine signaling in WAT in middle aged mice. Furthermore, transcriptomic profiling highlights that DPR induces biological processes that are sex-dependent on energy storage and usage. The work is supported by the National Institute on Aging (NIA) of the National Institutes of Health (NIH) - MOSAIC– NIA R00AG070273.
THE INTERACTION BETWEEN SHORT SLEEP AND EXERCISE FREQUENCY WITH HEART RATE VARIABILITY: CROSS-SECTIONAL STUDY
Authors: Fein Taylor , Thalil Muhammad , Lee Soomi 
Published: January 2025

Abstract
Exercise has been shown to be a powerful tool that can improve cardiovascular health. Both exercise and adequate sleep have been associated with increased heart rate variability (HRV), while insufficient amounts of both are associated with decreased HRV. Yet, the combined influence of exercise and sleep on HRV is less clear. This study explores if exercise levels and sleep duration interact to be associated with HRV. 391 adults (Mage=57yrs) from the Midlife in the United States Biomarker study 2004-2009 provided sleep actigraphy, electrocardiogram (ECG) HRV measurements and answered questions on exercise habits. Participants were grouped as short (&lt; 6 hours) or adequate sleepers (≥ 6 hours) and inadequate (&lt; 150 minutes per week) or adequate exercise frequency (≥150 minutes per week) based on CDC guidelines. ANCOVA analysis adjusted for demographic and health-related covariates was used to examine the interaction between sleep duration and exercise frequency on HRV. There were no significant individual associations of sleep duration or exercise frequency with HRV, however combined associations were found. For individuals with less than 6 hours of sleep, those with inadequate exercise frequency had significantly lower HF-HRV (B=-0.59, SE = 0.21, p=0.005) and RMSSD (B=0.29, SE = 0.10, p=0.003) compared to those with adequate exercise. Among adequate sleeper’s, no significant differences in HRV were observed between each exercise group. Findings suggest that for those with short sleep, lack of exercise may exacerbate the negative consequences of short sleep on HRV. Future studies should explore whether and how exercise intensity may change this relationship.
THE MODERATING RELATIONSHIP BETWEEN FUTURE SELF-CONTINUITY AND NUMERACY ON RETIREMENT SAVINGS
Authors: Mooney Laken , Best Ryan 
Published: January 2025

Abstract
Worldwide, lifespan is increasing while birth rates are declining resulting in an increasing proportion of older adults in the population. This demographic shift will manifest in an increased proportion of adults in retirement who will rely on non-employment sources of income. Though Social Security provides a key source of retirement income, it is often insufficient and requires supplementation by other sources. Since the late 1970s, the most common retirement savings programs have largely shifted from employers (e.g., pensions) to individuals (e.g., 401k and IRA programs). As such, a greater responsibility for retirement savings now falls on individuals and is more susceptible to variance in individual decision making. Individual difference factors which predict retirement savings include numeracy, the ability to understand and work with numbers, and future self-continuity (FSC), the sense of connectedness we have to our future selves. Using a zero-inflated Poisson model to analyze data from the RAND American Life Panel (n=798), we found a significant interaction between numeracy and FSC when predicting retirement savings (p&lt;.001) after controlling for age and income. Among those that had retirement savings, increased numeracy predicted greater savings for individuals with high, but not low, FSC. This demonstrates that highly numerate individuals appear to have the skills necessary to maximize retirement savings but may not utilize these skills unless they have a strong connection to their future self. Results are discussed in light of the current landscape of retirement preparation and how to best promote individual saving.
THE RELATIONSHIP BETWEEN CELLULAR GLYCOLYSIS AND AGE IN BLOOD CELLS OF ADULTS
Authors: Keri Ben , Phang Howard , Bergstrom Jaclyn , Dozier Stephen , Scandalis Lina , Molina Anthony 
Published: January 2025

Abstract
Mitochondrial dysfunction is a hallmark of aging that leads to inefficient cellular energy production, causing a shift towards aerobic glycolysis termed the Warburg Effect. While most studies examined the effect of aging on oxidative phosphorylation (OXPHOS), the relationships between glycolysis and age are less understood. Blood cells are a promising avenue for establishing biomarkers for their accessibility and versatility. We hypothesized that blood cells from older participants would have higher glycolytic function compared to blood cells from younger donors. We used blood collected from adults across the human lifespan through the San Diego Nathan Shock Center. We isolated platelets, peripheral blood mononuclear cells (PBMCs), monocytes, and lymphocytes, and measured glycolytic proton efflux rate (glycoPER) using the Agilent SeahorseXFe96 which is comparable to lactate efflux rate. Pearson correlation analysis showed moderate positive associations between age and glycoPER for platelets (r=0.31, p=0.48) and PBMCs (r=0.44, p=0.004) in women. There were no correlations between age and glycoPER for monocytes or lymphocytes in women, or any cell type in men. Our findings support our hypothesis that the glycolytic function of cells from older donors is higher than that of younger donors, but only for certain cell populations in women and not for men. Interestingly, gPER was positively correlated with OXPHOS in most cell types, in contrast to the Warburg Effect premise. In conclusion, our study suggests a relationship between glycolysis and age that should be further investigated in the context of age-related bioenergetic decline.
THE RELATIONSHIP BETWEEN LIVING ALONE AND STRESS FROM A LIFE COURSE PERSPECTIVE
Authors: Lim Junyub , Andel Ross , Sheardova Katerina , Pavlik Jan , Amlerova Jana , Hort Jakub 
Published: January 2025

Abstract

Background/objectives
Social isolation may affect psychological well-being, but understanding this link across adulthood is limited. We examined living alone in relation to dealing with daily stress among younger, middle-aged, and older adults.

Methods
Data from Terrapino, a new mobile application designed to support cognitive health, were utilized. Psychological well-being was assessed with a 10-item index of dealing with daily stress over the past month (get angry, feel like things are piling up, feel like being on top of things, etc.) reported as never/sometimes/often/very often. Demographic, health, and lifestyle information was also collected.

Results
Complete data were available for 6,154 users who gave consent to allow reports of aggregate data (mean=57.2±14.4, range 18-103 years, 73% were female). Users were categorized as young (18-30 years, n=331), middle-aged (31-60 years, n=3,058), and older (61+ years, n=2,765) adults, of whom 45% (52% male/42% female), 20% (17% male/21% female), and 32% (15% male/39% female) young, middle-aged, and older adults, respectively, lived alone. Controlling for sex, education, and comorbidity, young adults who lived alone had poorer ability to deal with daily stress (Estimate=0.22, p&lt;.05), no differences existed among middle-aged adults (p&gt;.05) and better ability to deal with daily stress emerged among older adults living alone (Estimate=-0.11, p&lt;.01).

Discussion
Using data from a freely available mobile application, young users who lived alone dealt with daily stress relatively poorly, whereas their older counterparts showed opposite trends regardless of comorbidity. This study sets the stage for research into mobile application use to improve well-being of older adults living alone.
THE ROLE OF FILIAL PIETY IN AGING AND CAREGIVING AMONG CHINESE AND CHINESE AMERICANS
Authors: Xiao Chunhong , Jablonski Rita , Patrician Patricia , Montgomery Aoyjai , Wang Youhua , Markaki Adelais 
Published: January 2025

Abstract
Understanding filial piety as it pertains to aging and caregiving among Chinese and Chinese Americans (CCAs) is expected to bridge the cultural chasm in health care and improve the quality of rendered services. This concept analysis aims to understand the role of filial piety relevant to caring for aging CCAs and to propose an operational definition. We used four databases and followed Walker and Avant’s method for data extraction and analysis. A total of 26 studies met inclusion criteria and were chosen for synthesis. Synthesis of evidence identified four antecedents: (a) filial obligation as a ‘cultural gene’, (b) sense of altruism, (c) familial solidarity, and (d) societal expectation of ‘birth right’. Attributes included: familial material and emotional support, obedience, pious reverence, and societal norm. Consequences were related to caregiver burden, psychological and physical well-being, quality of life, and health equity. Operational definition of filial piety is: an intrinsic desire of adult children to support parents/elders materially and emotionally as well as an extrinsic desire to adhere to the Chinese societal moral tenet to honor family and be honorable children. Future study should examine dual roles of filial piety as a moderator of role appraisal to caregiver burden and as a mediator of resources. The permeating cultural value of filial piety affects help-seeking behavior, caregiving, family relationships, and caregiver health for CCAs. Understanding the meaning, importance, and effect of filial piety for Asians and CCAs is essential for healthcare providers to provide culturally sensitive social and psychological support to caregivers.
TIME SPENT FOR OTHERS: VARIED ASSOCIATIONS WITH WELL-BEING ACROSS TWO TIME SCALES AND SOCIODEMOGRAPHIC GROUPS
Authors: Cho Kyoungmin , Almeida David , Lee Soomi 
Published: January 2025

Abstract
Existing research on spending time for others yields inconsistent findings regarding its effects on well-being. Some studies report positive effects, while others find negative effects. To address this inconsistency, our study explored whether spending time for others differentially impacts overall eudaimonic well-being and day-to-day hedonic well-being, considering potential differences across sociodemographic groups. 665 participants (Mage=48.27) in the Midlife in the United States Study completed both monthly survey and eight-day diary survey. Monthly and daily time spent for others, overall eudaimonic well-being (psychological and social domains), and daily hedonic well-being (positive affect, negative affect, daily stressors) were measured. OLS regression and multilevel models evaluated the associations of time spent for others with eudaimonic and hedonic well-being at the two time scales, adjusting for sociodemographic and health covariates (e.g., age, gender, education, self-reported physical health, marital status, day of week, and number of missed diary). Results indicated that, at the monthly level, participants who spent more time for others reported higher overall psychological and social well-being. However, at the daily level, they experienced more negative affect and stressors, with these effects more pronounced in men and adults under 56-year old. This study clarifies inconsistencies in prior research, highlighting differential associations of spending time for others with individual well-being across different time scales and sociodemographic groups. While short-term responses tend to be negative, particularly among men and younger individuals, long-term outcomes appear to be positive.