bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and quality evaluation of a micronutrient rich traditional Indian product by utilization of locally available food resources
Authors: OJHA KOMAL , SINGH VISHAKHA 
Published: August 2022

ABSTRACT
Malnutrition is a severe matter of concern among various countries due to modern lifestyles, especially the consumption of rapidly processed fast food. In 2018, a WHO and UNICEF study concluded that the SDG objective of eradicating all forms of malnutrition by 2030 was aspirational but unattainable and set targets for malnutrition indicators up to 2030 based on current trends. The present situation demands products rich in micronutrients, meet growth and development requirements, and are readily acceptable. A critical reason for such use of rice flour is its nonallergenic nature. A small proportion of the population is allergic to wheat gluten. Rice is widely used in baking for such wheat-intolerant people, i.e., those suffering from the coeliac disorder. Its nonallergenic property also makes rice one of the first cereals to be used in infant feeding. In this scenario, rice flour is preferred as the foremost choice for required sensory acceptability and a low-cost diet. Food-based approaches are recognised as an essential part of an urgently needed, more comprehensive strategy for improving nutrition by increasing the availability and consumption to combat calcium, iron, phosphorus and other micronutrient deficiencies. The combination of rice flour, beaten rice, banana, jaggery contains a high amount of energy protein with calcium and iron content. Such a combination of foods can enhance the nutritive value of homemade products, which can be beneficial for the malnourished population. The present study was undertaken to develop anarsa by combining banana, jaggery and rice flour using the air frying method. The developed product was evaluated for sensory attributes by a panel of 10 judges on 9 points hedonic rating scale. The calculated nutritive value from Indian Food Composition Tables (2017) showed that the product (100g) was not only had a high level of macronutrients, i.e. energy (3123.6 Kcal), carbohydrate (172.5g), protein (12.24g), fat (4.52g) but also rich in micronutrients like calcium (262.8mg), phosphorus (294.4mg) and iron (6.52mg). The product was packed and stored for 15 days at ambient temperature in an airtight container. At pre-evaluation, all the sensory parameters at the 9-point hedonic rating scale were found to be highly acceptable between 'liked moderately' (rating 8) to 'liked very much. After 15 days of storage, all sensory parameters changed and were lying in-between 'liked slightly' (rating 6) to 'liked moderately' (rating 7). The changes in sensory parameters may be due to the darkening of jaggery and changes in the flavour of the product. Thus, it can be concluded that the development and consumption of novel foods from rice flour in combination with other foods like may banana, jaggery and poppy seeds may provide cost-effective and acceptable options for combating macro and micronutrient deficiencies.

Keywords: Rice flour, jaggery, banana, energy dense, mineral profile, sensory evaluation, malnutrition
Effect of tetraataxiometric posturography programs (TETRAX) on stroke patients with impaired standing balance
Authors: SHARMA BHAWNA , GAUR PRATEEK , KADIAN POONAM 
Published: August 2022

ABSTRACT
Patients are suffering from stroke experience balance dysfunction leading to poor weight shifts and reduced weight bearing on the affected lower limb. The Tetrax biofeedback system is a Centre of Pressure-controlled, video game-based exercise system designed for patients with balance dysfunction. Objective: This study aimed to investigate the effects of using Tetrax balance games and conventional rehabilitation on the balance and mobility of subjects with impaired standing balance due to stroke. Design: Pretest-posttest Randomized Clinical Trial Method: A total of thirty patients (including male and female) who have suffered a stroke at least six months back, diagnosed with hemiplegia within the age group of 35-65 years with MMSE Score = 24 were recruited. Six subjects did not give their consent. Subjects were assigned to Group 1 (test group) and Group 2 (control group), using Convenience sampling. Group 1 (test group) consisted of 12 subjects (both male and female) and received conventional therapy and tetrax sessions. Group 2 (control group) consisted of 12 subjects (both male and female) and received only conventional therapy. All participants received conventional outpatient rehabilitation therapy (which accounted for an average of 60 minutes of physiotherapy for the control group and 40 minutes for the test group per day) three days a week in an outpatient setting. The test group received additional Tetrax biofeedback balance training three days per week (20 minutes per day) for four weeks in the same outpatient setting. The Tetrax system was equipped with four independent force plates under the toes and heels. The outcome measures of the study were BBs and FIMS. All outcome measures were evaluated pretest and posttest. Result: The means standard deviations of Improvement in BBS in test and control groups are 3.83 4.64 and 1.25 1.28, respectively. On applying the t-Test, we found the mean difference of 0.077 of Improvement in BBS in the test and control group is not significant. The means standard deviations of Improvement in FIMS in test and control groups are 2.83 2.24 and 1.75 1.21, respectively. On applying the t-Test, we found the mean difference of 0.156 of Improvement in FIMS in the test and control group is not significant. Conclusion: The current study found that both groups—those receiving only conventional therapy and those receiving a combination of tetrax and conventional therapy—improved their balance significantly, although there was no significant difference between them.
Keywords: Stroke, Tetrax, Balance, Weight shift in lower limbs, Postural Balance.
Effectiveness of active release techniques in frozen shoulder – a review article
Authors: GANGWAR KM. DIVYA , SHARMA RITA 
Published: August 2022

ABSTRACT
Frozen Shoulder (FS) is also known as adhesive capsulitis with unknown aetiology, which are specified by the limitation of both active, passive ROM is in the shoulder. It is most general cause of shoulder pain which effects between 2% to 5% of the common population and 10% to 20 % population with diabetes. FS is most generally looked at in women's than in males between 40-60 years of age; in 20-30% of cases, it can be both sides. The Active release technique is a non-invasive soft tissue method that simultaneously finds and separates scar tissue. In our review article, mostly all studies reported the effectiveness of the active release technique in orthopaedic conditions, but more research is needed.
Keywords: Active Release Technique, Frozen Shoulder, Adhesive Capsulitis, Musculoskeletal Disorders
Stolen elections: How conspiracy beliefs during the 2020 American presidential elections changed over time
Authors: Wang Haiyan , van Prooijen Jan‐Willem 
Published: August 2022

AbstractConspiracy beliefs have been studied mostly through cross‐sectional designs. We conducted a five‐wave longitudinal study (N = 376; two waves before and three waves after the 2020 American presidential elections) to examine if the election results influenced specific conspiracy beliefs and conspiracy mentality, and whether effects differ between election winners (i.e., Biden voters) versus losers (i.e., Trump voters) at the individual level. Results revealed that conspiracy mentality kept unchanged over 2 months, providing first evidence that this indeed is a relatively stable trait. Specific conspiracy beliefs (outgroup and ingroup conspiracy beliefs) did change over time, however. In terms of group‐level change, outgroup conspiracy beliefs decreased over time for Biden voters but increased for Trump voters. Ingroup conspiracy beliefs decreased over time across all voters, although those of Trump voters decreased faster. These findings illuminate how specific conspiracy beliefs are, and conspiracy mentality is not, influenced by an election event.
Mitochondrial‐Targeting Vitamin B3 Ameliorates the Phenotypes of Parkinson's Disease In Vitro and In Vivo by Restoring Mitochondrial Function
Authors: Xin Chenqi , Yang Naidi , Ding Yaqi , Han Linqi , Zhou Zhiqiang , Guo Xiaolu , Fang Zhijie , Bai Hua , Peng Bo , Zhang Chengwu , Li Lin 
Published: August 2022

AbstractParkinson's disease (PD) is the second most common neurodegenerative disease and is characterized by progressive dopaminergic neuron loss, which affects millions of people worldwide, especially elderly individuals. Mitochondrial dysfunction is believed to be one crucial causative factor of PD. Therefore, restoring mitochondrial function is highly recommended for the treatment of PD. Herein, it is found that vitamin B3 (VB3) protects the dopaminergic cell line SH‐SY5Y against rotenone‐induced apoptosis by restoring mitochondrial dysfunction. To further improve the efficacy, a derivative of VB3, mitochondrial‐targeting VB3 (Mito‐VB3), is developed. It is demonstrated that Mito‐VB3 rescues SH‐SY5Y cells from the neurotoxicity of oxidative stress. More importantly, Mito‐VB3 ameliorates the phenotypes of the Drosophila PD model. Mechanistically, Mito‐VB3 enhances nicotinamide adenine dinucleotide (NAD+) levels, reduces ROS generation, elevates ATP levels, and restores mitochondrial membrane potential. Meanwhile, Mito‐VB3 promotes mitochondrial biogenesis by activating the NAD+/SIRT1/PGC1α pathway. In summary, the results demonstrate that Mito‐VB3 displays remarkable neuroprotective effects in the cell and Drosophila PD models and that Mito‐VB3 might serve as a potential therapeutic candidate for the treatment of PD and other mitochondrial dysfunction‐related diseases.
Global, regional, and national trends of dementia incidence and risk factors, 1990–2019: A Global Burden of Disease study
Authors: Avan Abolfazl , Hachinski Vladimir 
Published: August 2022

AbstractBackgroundAn ample literature documents the growing prevalence of dementia and associated costs. Less attention has been paid to decreased dementia incidence in some countries.MethodsWe analyzed trends in age‐standardized dementia, stroke, and ischemic heart disease (the triple threat) incidence rates and population attributable fraction of death and disability attributable to 12 risk factors in 204 countries and territories and 51 regions using Global Burden of Disease 2019 data.ResultsDuring 1990 to 2019, dementia incidence declined in 71 countries; 18 showed statistically significant declines, ranging from –12.1% (95% uncertainty intervals –16.9 to –6.8) to –2.4% (–4.6 to –0.5). During 2010 to 2019, 16 countries showed non‐significant declines. Globally, the burden of the triple threat attributable to air pollution, dietary risks, non‐optimal temperature, lead exposure, and tobacco use decreased from 1990 to 2019.ConclusionThe declining incidence of dementia in some countries, despite growing prevalence, is encouraging and urges further investigation.
Diatomic Pd−Cu Metal‐Phosphorus Sites for Complete N≡N Bond Formation in Photoelectrochemical Nitrate Reduction
Authors: Sun Jie , Yang Hanxue , Gao Weiqi , Cao Tongcheng , Zhao Guohua 
Published: August 2022

AbstractThe synergistic effect of bimetallic heterogeneous catalysis in the reaction of nitrate reduction to nitrogen has been widely discussed, but it is still not clear how this effect works at the atomic scale, hindering the rational design of high‐performance catalysts. Here, for the first time, 2D phosphorene was used as a giant P ligand to confine high‐density PdCu dual‐atom to form a unique PdCuP4 coordination structure, and this catalyst achieves 96.3 % NO3− removal rate and 95.2 % N2 selectivity. In situ characterization combined with density functional theory (DFT) calculations show that the PdCu dual‐atom form covalent‐like bonds with adjacent P atoms, reducing the adsorption energy of the reactants. The synergistic effect of PdCu dual‐atom promotes the breaking of N−O bond, and the short bond length of ≈3 Å between PdCu atoms accelerates the transfer of NO2−, and eventually the two Pd−N adjacent to the surface of Pd rapidly combine to form N2.
Detection of Ethylene with Defined Metal Complexes: Strategies and Recent Advances
Authors: Jensen Katrina H. , Michel Brian W. 
Published: August 2022

AbstractDespite its relative simplicity, ethylene is an interesting molecule with wide‐ranging impact in modern chemistry and biology. Stemming from ethylene's role as a critical plant hormone, there has been significant effort to develop selective and sensitive molecular sensors for ethylene. Late transition metal complexes have played an important role in detection strategies due to ethylene's lack of structural complexity and limited reactivity. Two main approaches to ethylene detection are identified: (1) coordination‐based sensors, wherein ethylene binds reversibly to a metal center, and (2) activity‐based sensors, wherein ethylene undergoes a reaction at a metal center, resulting in the formation and destruction of covalent bonds. Herein, we describe the advantages and disadvantages of various approaches, and the challenges remaining for sensor development.
The effectiveness of an attention‐based intervention for school‐aged autistic children with anger regulating problems: A randomized controlled trial
Authors: Clifford Pamela , Gevers Carolien , Jonkman Kim M. , Boer Frits , Begeer Sander 
Published: August 2022

AbstractAnger regulation is a challenge for children with autism spectrum disorders (ASD). We investigated if attention‐based cognitive behavioral treatment, based on mindfulness cognitive therapy (MBCT) and dialectical behavior therapy (DBT), reduces aggressive behavior and improves anger coping in school‐aged autistic children (n = 51). Children were randomized to an active‐control or a treatment condition. The treatment included nine weekly sessions attention‐based individual therapy. Parents in both conditions received three weekly psychoeducation group sessions to heighten awareness of expressed emotion (EE). For aggressive behavior, treatment reduced temper tantrums and arguing. No effect was found on destroying things and physical violence. For anger coping, treatment increased adaptive coping strategies of diffusion and social support seeking, but had no effect on assertion, rumination, and maladaptive coping direct anger out and avoidance. Treatment did not impact secondary outcome measures concerning children's quality of life (QoL) and parental stress‐levels and psychological well‐being. In conclusion, school‐aged autistic children are able to acquire self‐regulation skills reducing temper tantrums and arguing and increasing the use of adaptive anger coping strategies. The intervention shows potential to improve behavior and regulation, but little transfer to other domains. Limitations and future directions involving the child's social environment, including parents, siblings, and teachers are discussed.Lay SummaryChildren on the autism spectrum often show aggressive behavior. Treatment can train children to be more aware of their emotions. This study found that this can help reducing temper tantrums and arguing and increasing some coping skills, though no impact was found on several other domains of aggression and coping.
How to increase sustainable production in the food sector? Mapping industrial and business strategies and providing future research agenda
Authors: Sadraei Razieh , Biancone Paolo , Lanzalonga Federico , Jafari‐Sadeghi Vahid , Chmet Federico 
Published: August 2022

AbstractFood waste is a tremendous systemic challenge, mainly at all stages of consumption and the supply chain process. In recent years, the global food supply challenge has called for new methods to decrease food waste or recover them to more valuable materials. Indeed, understanding the techniques for reducing and recovering food waste provides insights into exploring the impact of waste food recovery on the environment. This paper aims to review the literature on food waste in production processes. Hence, we employ a bibliometric and thematic analysis to explore a total number of 163 scientific articles published between 2000 and 2021. The present research uses the theoretical model of circular economy to analyse the literature on the topic both thematically and with cluster analysis. The results provide significant implications for academics and practitioners, drawing attention to a closer relationship between people and food waste, increasing the culture of the value of waste in all processes from agricultural production to distribution and consumption. Finally, it reiterates the need to emphasise the pollution caused by food production.
Modulating neuroinflammation through molecular, cellular and biomaterial‐based approaches to treat spinal cord injury
Authors: Lee Cheryl Yi‐Pin , Chooi Wai Hon , Ng Shi‐Yan , Chew Sing Yian 
Published: August 2022

AbstractThe neuroinflammatory response that is elicited after spinal cord injury contributes to both tissue damage and reparative processes. The complex and dynamic cellular and molecular changes within the spinal cord microenvironment result in a functional imbalance of immune cells and their modulatory factors. To facilitate wound healing and repair, it is necessary to manipulate the immunological pathways during neuroinflammation to achieve successful therapeutic interventions. In this review, recent advancements and fresh perspectives on the consequences of neuroinflammation after SCI and modulation of the inflammatory responses through the use of molecular‐, cellular‐, and biomaterial‐based therapies to promote tissue regeneration and functional recovery will be discussed.
Numerical Investigation of Steel‐LVL Timber Composite Beams
Authors: Romero Alfredo , Yang Jie , Hanus François , Odenbreit Christoph 
Published: August 2022

AbstractIn the last years, new connectors of steel‐concrete composite flooring systems have been developed and investigated to enhance the circularity and standardisation of building components. Recent studies showed that timber can be used as an alternative to the concrete slab in hybrid structures. However, the knowledge in steel‐timber composite flooring systems is still very limited. This contribution presents numerical investigations of steel‐LVL timber composite beams. The load deformation behaviour was determined through 3D finite element models. The design resistance of the composite beams was estimated analytically through a strain‐controlled approach. The results of this study show that the resistances obtained in the numerical models and the strain‐controlled approach are in good agreement. Moreover, obtained deflections and slip values were given at ultimate load.
Demountable Steel‐Concrete Composite Floors for Circular Economy: State of the Art and Design Principles
Authors: Pimentel Ricardo , Simões Rui , da Silva Luís Simões 
Published: August 2022

AbstractThe construction sector activities contribute to irreversible effects on the environmental systems. New forms of construction are needed to increase the circular economy and sustainability within the built environment. Steel‐concrete composite floors are not demountable, because the typical shear connection with welded studs is permanent. To avoid demolition and promote the reuse of the structural components, demountable shear connection systems need to be adopted. This article presents a literature review of different forms of demountable shear connection solutions and an overview of suitable design rules for such solutions.
PROTOCOL: The effectiveness of wilderness therapy and adventure learning in reducing anti‐social and offending behaviour in children and young people at risk of offending
Authors: Mohan Ashima , Malhotra Suchi , Narayanan Monisha , White Howard , Gaffney Hannah 
Published: August 2022

AbstractThis is the protocol for a Campbell systematic review. The objectives are as follows. The review will address the following research questions: (1) What are the long‐ and short‐term effects of wilderness therapy and adventure learning on anti‐social behaviour and violent and other offending behaviour? What factors explain any heterogeneity (i.e., moderate) these effects. What are the long‐ and short‐term effects of wilderness therapy and adventure learning on intermediate mental health and behaviour outcomes such as social skills and self‐regulation? What factors explain any heterogeneity (i.e., moderate) these effects? Factors such as setting (indoor/outdoor), quality of relationship with counsellors and the degree of the challenge element involved are important moderators of these effects, and help explain any observed heterogeneity across studies (2) What are the barriers and facilitators affecting the successful implementation of wilderness therapy and adventure learning programmes? (3) Are wilderness therapy and adventure learning interventions cost effective?
Content‐based image retrieval using color and a novel texture descriptor: orientational‐based local binary pattern
Authors: Baarab Nissrine , Chaouki Brahim E. L. Khalil , Masmoudi Lhoussaine 
Published: August 2022

SummaryThe increasing use of images and multimedia has led, in the past years, to a major growth of data and images to store. With this, comes the importance of having a way to facilitate the indexing and the retrieval of the images. In this article, we present a new method for content‐based image retrieval. The proposed approach is composed of two phases: first, a preselection of relevant images from the initial database based on HSV color space and using color moment information. The second phase relies on using the selected images from the first phase as a new database and extracting the texture feature using a novel descriptor called orientational‐based local binary pattern (OB‐LBP) derived from the traditional LBP texture feature technique. In the proposed descriptor (OB‐LBP) we compare each neighbor of the center pixel (of 3 × 3 window) with its three closest neighbors and form a binary code of three components for each pixel, then based on their directions we generate three images and produce the histogram to extract the final feature descriptor. Corel‐10 k and Wang's databases were used to evaluate the proposed method. The results show a significant improvement in the proposed method over existing methods.
Binding Energy Partition of Promising IRAK‐4 Inhibitor (Zimlovisertib) for the Treatment of COVID‐19 Pneumonia
Authors: Zapata‐Acevedo César A. , Guevara‐Vela José Manuel , Popelier Paul L. A. , Rocha‐Rinza Tomás 
Published: August 2022

AbstractThe technique of Fragment‐Based Drug Design (FBDD) considers the interactions of different moieties of molecules with biological targets for the rational construction of potential drugs. One basic assumption of FBDD is that the different functional groups of a ligand interact with a biological target in an approximately additive, that is, independent manner. We investigated the interactions of different fragments of ligands and Interleukin‐1 Receptor‐Associated Kinase 4 (IRAK‐4) throughout the FBDD design of Zimlovisertib, a promising anti‐inflammatory, currently in trials to be used for the treatment of COVID‐19 pneumonia. We utilised state‐of‐the‐art methods of wave function analyses mainly the Interacting Quantum Atoms (IQA) energy partition for this purpose. By means of IQA, we assessed the suitability of every change to the ligand in the five stages of FBDD which led to Zimlovisertib on a quantitative basis. We determined the energetics of the interaction of different functional groups in the ligands with the IRAK‐4 protein target and thereby demonstrated the adequacy (or lack thereof) of the changes made across the design of this drug. This analysis permits to verify whether a given alteration of a prospective drug leads to the intended tuning of non‐covalent interactions with its protein objective. Overall, we expect that the methods exploited in this paper will prove valuable in the understanding and control of chemical modifications across FBDD processes.