bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating the Application of the RE-AIM Planning and Evaluation Framework: An Updated Systematic Review and Exploration of Pragmatic Application
Authors: D'Lima Danielle , Soukup Tayana , Hull Louise 
Published: January 2022

BackgroundRE-AIM is one of the most widely applied frameworks to plan and evaluate the implementation of public health and health behavior change interventions. The objective of this review is to provide an updated synthesis of use of the RE-AIM (Reach Effectiveness Adoption Implementation and Maintenance) planning and evaluation framework and explore pragmatic use (i.e., partial application of the framework) and how this is reported.MethodsSystematic review. MEDLINE (R) and PsycINFO were searched, via the Ovid interface, between January 2011 and December 2017. Studies that applied RE-AIM as a planning and/or evaluation framework were included.ResultsOne hundred fifty-seven articles met inclusion criteria. One hundred forty-nine reported using RE-AIM for evaluation, three for planning and five for planning and evaluation. Reach was the most frequently reported dimension (92.9%), followed by implementation (90.3%), adoption (89.7%), effectiveness (84.5%), and maintenance (77.4%). One hundred forty-seven/one hundred fifty-seven articles originated from high-income economy countries. Within a sub-set analysis (10% of included articles), 9/15 articles evaluated all dimensions. Of the 6/15 articles that did not evaluate all dimensions, five provided no justification for pragmatic application.ConclusionsRE-AIM has gained increased use in recent years and there is evidence that it is being applied pragmatically. However, the rationale for pragmatic use is often not reported.Systematic Review RegistrationPROSPERO (CRD42017054616).
Effects of Mindfulness Exercise Guided by a Smartphone App on Negative Emotions and Stress in Non-Clinical Populations: A Systematic Review and Meta-Analysis
Authors: Wu Jinlong , Ma Yudan , Zuo Yifan , Zheng Kangyong , Zhou Zhenhui , Qin Yifan , Ren Zhanbing 
Published: January 2022

BackgroundStudies have acknowledged that mindfulness exercise guided by a smartphone app has a positive impact on mental health and physical health. However, mindfulness guided by a smartphone app on mental health is still in its infancy stage. Therefore, we conducted a meta-analysis evaluating the effect of mindfulness intervention guided by a smartphone app on negative emotions and stress in a non-clinical population with emotional symptoms.MethodsWe searched major databases, namely, Web of Science, PubMed, Scopus, China National Knowledge Infrastructure (CNKI), and Wanfang, to identify all of the relevant studies published in English or Chinese from their inception until November 9, 2021. The methodological quality of the included studies was assessed with Cochrane risk-of-bias bias assessment tool. Two researchers independently conducted document retrieval, study selection, data extraction, and methodological quality evaluation.ResultA total of eight studies were included in the study, with 574 subjects (experimental group: 348; control group: 226). A random effects model was selected to combine effect sizes. The results of the meta-analysis showed that mindfulness exercise guided by a smartphone app reduced negative emotions [standardized mean difference (SMD) = −0.232, 95% CI: −0.398 to −0.066, p = 0.006], depressive symptoms (SMD = −0.367, 95% CI: −0.596 to −0.137, p = 0.002), and anxiety symptoms (SMD = −0.490, 95% CI: −0.908 to −0.071, p = 0.022).ConclusionsThe findings indicate the potentially beneficial effect of mindfulness exercise guided by a smartphone app on symptoms of depression and anxiety among individuals in a non-clinical population with emotional symptoms. Considering the small number and overall methodological weakness of the included studies and lack of randomized controlled trials (RCTs), the results should be interpreted with caution, and future rigorously designed RCTs are warranted to provide more reliable evidence.
Working Safely in the Trades as Women: A Qualitative Exploration and Call for Women-Supportive Interventions
Authors: Curtis Hannah M. , Meischke Hendrika W. , Simcox Nancy J. , Laslett Sarah , Monsey Lily M. , Baker Marissa , Seixas Noah S. 
Published: January 2022

BackgroundConstruction work offers women economic advancement and self-fulfillment opportunities, but multiple barriers prevent their increased representation in the industry. This study used qualitative methods to identity key physical and psychosocial safety hazards affecting tradeswomen.MethodsThree focus groups were held in 2015 with 19 tradeswomen in Washington State. Groups discussed workplace hazards and solutions to make the trades safer for women. Discussions were recorded, transcribed, and two independent reviewers analyzed themes.ResultsParticipants identified myriad physical and psychosocial hazards including a dangerous work environment, inadequate personal protective equipment, gender discrimination, and fear of layoff for reporting concerns. Participants identified mentorship as a potential intervention to overcome some of these barriers.ConclusionFindings suggest that the industry's work environment can be hostile and unsupportive for women, contributing to tradeswomen's injury risk and psychological distress. Future research and interventions should focus on understanding the relationships between and mediating the negative impact of women's physical and psychosocial workplace hazards. Results from these focus groups inspired a randomized control trial to study the impact mentorship has on decreasing physical and psychosocial hazards for women in construction, and improving retention.
Can COPD Exacerbations Be Picked Up Early via a Weekly Medication Question Through a Smartphone Application?
Authors: Blondeel Astrid , Demeyer Heleen , Breuls Sofie , Wuyts Marieke , Glorie Lies , De Maeyer Nikolaas , Janssens Wim , Troosters Thierry 
Published: January 2022

BackgroundExacerbations affect the disease trajectory of patients with COPD and result in an acute drop of functional status and physical activity. Timely detection of exacerbations by non-medical healthcare professionals is needed to counteract this decline. The use of digital health applications in patient interaction allows embedded detection of exacerbations. However, it is unknown if this is an effective way to pick up exacerbations.MethodWe investigated the detection of exacerbations in patients with COPD enrolled in a physical activity coaching program, by prompting a weekly question on changes in medication via the smartphone application. Data on response rate and occurrence of exacerbations were collected.ResultsResponse rate to the medication question, evaluated in 42 patients, was 72% (n = 497). A change in medication was reported through the smartphone application in 38 (7.6%) of the answered questions. The response rate was significantly lower at 6 months follow-up compared to the first month (p =0.03). When evaluating the occurrence of adverse events in a subset of patients who completed 6 months of follow-up (n = 27), 18 exacerbations were registered in eight patients, of which 10 of these exacerbations (56%) were picked up by the medication question in the coaching application.ConclusionElectronic interaction through a weekly medication question, embedded in a smartphone application, is feasible to support the detection of the occurrence of COPD exacerbations and can be used complementary to regular forms of detecting exacerbations. Compliance and smartphone literacy should be optimized when further using this method to report on COPD exacerbations.
Voluntary Wheel Running Reduces Vesicle Development in an Endometriosis Animal Model Through Modulation of Immune Parameters
Authors: Appleyard Caroline B. , Cruz Myrella L. , Velazquez-Cruz Johnathan , Rivera-Mendez Raquel M. , Jimenez-Garcia Juan G. , Rivera Luis A. , Mendez-Casillas Maria del Mar , Flores Idhaliz , Al-Nakkash Layla , Chompre Gladys 
Published: January 2022

IntroductionEndometriosis is a chronic gynecological disorder characterized by the growth of endometrial glands and stroma outside the endometrial cavity producing inflammation and pain. Previously we demonstrated that modulation of the hypothalamic pituitary adrenal (HPA) axis exacerbates the development and severity of this condition. A physically active lifestyle has been shown to confer health benefits in many chronic conditions by potentially acting as a stress buffer, thus we hypothesized that voluntary physical exercise can “realign/reset” the HPA axis resulting in reduced endometriosis symptoms in an animal model.MethodsEndometriosis was induced in female Sprague Dawley rats by implanting uterine tissue next to the intestinal mesentery on day 0. Sham controls received sutures only. One group of endometriosis animals had access to a running wheel for 2 weeks prior to endometriosis induction until time of sacrifice at day 60. Sham and endometriosis controls received no exercise. All animals were examined for developed vesicles which were collected and measured. Uterine tissue was analyzed for cellular infiltration. Brain, liver, spleen, adrenal glands, leg muscles, and fat were collected, along with peritoneal fluid and blood.ResultsEndometriosis animals developed vesicles in 86.96% of the implants with significantly increased mesenteric fat compared to sham (p &lt; 0.05). Exposure to exercise significantly decreased the size (p &lt; 0.01) and number (p &lt; 0.05) of vesicles that developed, as well as the mesenteric fat (p &lt; 0.01). Exercised animals had higher levels of lactoferrin in peritoneal fluid, and decreased serum fractalkine and leptin. Exercise significantly increased estrogen alpha receptor expression levels (p &lt; 0.01), while significantly decreasing estrogen receptor beta expression (p &lt; 0.01) and macrophage infiltration (p &lt; 0.05) in vesicles compared to non- exercised animals.ConclusionsOur results suggest that voluntary physical activity might protect against endometriosis and alleviate the associated inflammation via immune modulation of the HPA axis. This offers the potential for further exploration of exercise as a complementary therapy in endometriosis patients.
Individuals at Risk of Exercise Addiction Have Higher Scores for Depression, ADHD, and Childhood Trauma
Authors: Colledge Flora , Buchner Ursula , Schmidt André , Wiesbeck Gerhard , Lang Undine , Pühse Uwe , Gerber Markus , Walter Marc 
Published: January 2022

BackgroundExercise addiction is increasingly being recognized as a psychologically and physically burdensome set of symptoms. However, little is known about the psychiatric profiles of individuals who are at risk. It is well-established that individuals affected by substance use disorders frequently suffer from depression, attention deficit hyperactivity disorder (ADHD), and experiences of childhood trauma. The aim of this study is to determine whether this pattern of psychiatric disturbance is also present in individuals at risk for exercise addiction.MethodsIndividuals exercising for 10+ h/week were divided into those at risk and not at risk for exercise addiction based on their scores on the Exercise Dependence Scale (EDS). Demographic data and scores on the Beck Depression Inventory (BDI), a measure for ADHD in adults and the Childhood Trauma Questionnaire (CTQ) were also gathered.ResultsOne hundred and twenty-three individuals agreed to participate in the study, and completed the questionnaires. Twenty-nine (23.6%) of these individuals were classed as at risk for exercise addiction. There was a statistically significant difference between the at-risk and not at-risk groups on the combined dependent variable after controlling for hours of exercise per week, F(3, 95)= 10.198, p = 0.00, Wilk's Λ = 0.756, partial η2 = 0.244. Compared to those not at risk, individuals at risk for exercise addiction had significantly higher scores for symptoms of depression [t(121) = 4.944, p = 0.000], ADHD [t(121) = 2.915, p = 0.004], and childhood trauma [t(121) = 2.297, p = 0.024].ConclusionOur results suggest that exercise addiction may be accompanied by a disturbed psychiatric profile consistent with other addictive disorders. Clinical interviewing in individuals at risk for exercise addiction is a valuable and worthwhile next step in characterizing this phenomenon.
Proctologic Surgery Prioritization After the Lockdown: Development of a Scoring System
Authors: Pietroletti Renato , Gallo Gaetano , Muselli Mario , Martinisi Giovanbattista , Cofini Vincenza 
Published: January 2022

IntroductionThe coronavirus disease 2019 (COVID-19) pandemic has shown a very critical impact on surgical procedures all over the world. Italy faced the deepest impact from the beginning of March 2020. Elective operations, screening, and follow-up visits had been suspended giving priority to urgent and oncologic surgery.PatientsAn observational study was carried out in the Surgical Coloproctology Unit of the Val Vibrata Hospital on 152 patients awaiting a proctological surgical treatment during the national lockdown.MethodsIn order to monitor the health status of patients and reschedule postlockdown surgical activities, patients were interviewed by telephone submitting a questionnaire based upon the judgment of an expert senior clinician. Following the interview, we calculated a severity index for all the proctologic diseases (hemorrhoidal disease, anal fissure, anal sepsis, slow transit or obstructed defecation, incontinence), classifying the patients according to the score. Mean age of patients was 53 (±16) years, and there were 84 males (55.3%) and 68 females (44.7%). In total, 31% of our patients suffered from anal fissure, 28% suffered from hemorrhoidal disease, 14% suffered from anal sepsis, and the remaining patients suffered from benign anorectal diseases to a lesser extent.ResultsA total of 137 patients were available and divided into three classes: priority surgery (PS) with 49 patients (36.2%), deferrable surgery (DS) with 25 patients (18.1%), and long-term surgery (L-TS) with 63 patients (45.6%). There was a significant correlation between the perceived health status reported during the interview and the priority class index (Spearman's rho = 0.97, p &lt; 0.001).Differences related to age and sex were not significant (F-test = 0.43, p = 0.653; chi-squared test = 0.693, p = 0.707). 49 patients in class PS needed a prompt surgical treatment, while 24 patients allocated in class DS and 65 patients allocated in class L-TS could wait for a new ride plan for surgery.ConclusionNew tools, such as this simple score obtained during the telephone interview, can be useful for prioritization of patients on the waiting list for surgical coloproctology after the lockdown without further clinical examination and hospital access.
In Vitro Potential of Clary Sage and Coriander Essential Oils as Crop Protection and Post-Harvest Decay Control Products
Authors: Raveau Robin , Fontaine Joël , Soltani Abir , Mediouni Ben Jemâa Jouda , Laruelle Frédéric , Lounès-Hadj Sahraoui Anissa 
Published: January 2022

Owing to their various application fields and biological properties, natural products and essential oils (EO) in particular are nowadays attracting more attention as alternative methods to control plant pathogens and pests, weeds, and for post-harvest applications. Additionally, to overcome EO stability issues and low persistence of effects, EO encapsulation in β-cyclodextrin (β-CD) could represent a promising avenue. Thus, in this work, the EO distilled from two aromatic plants (Salvia sclarea L. and Coriandrum sativum L.) have been evaluated in vitro for their antifungal, herbicidal and insecticidal activities, against major plant pathogens and pests of agronomical importance. Both plants were grown on unpolluted and trace-element-polluted soils, so as to investigate the effect of the soil pollution on the EO compositions and biological effects. These EO are rich in oxygenated monoterpenes (clary sage and coriander seeds EO), or aliphatic aldehydes (coriander aerial parts EO), and were unaltered by the soil pollution. The tested EO successfully inhibited the growth of two phytopathogenic fungi, Zymoseptoria tritici and Fusarium culmorum, displaying IC50 ranging from 0.46 to 2.08 g L−1, while also exerting anti-germinative, herbicidal, repellent and fumigant effects. However, no improvement of the EO biological effects was observed in the presence of β-CD, under these in vitro experimental conditions. Among the tested EO, the one from aerial parts of coriander displayed the most significant antifungal and herbicidal effects, while the three of them exerted valuable broad-range insecticidal effects. As a whole, these findings suggest that EO produced on polluted areas can be of great interest to the agricultural area, given their faithful chemical compositions and valuable biological effects.
MeV Cluster Ion Beam–Material Interaction
Authors: Kaneko Toshiaki 
Published: January 2022

This paper treats the characteristic topics of MeV/atom cluster ion beams produced using tandem accelerators both in the production stage and in the penetration stage from the viewpoint of fundamental processes. The former is related to atomic collisions in that production and decay of a cluster ion Cn+ (n=1−4) colliding with a charge-changing rare gas underlined through the electron-loss process. Regarding the latter, relatively small carbon clusters Cn+ (n=2−10) are treated. The reduction effect of the average charge of cluster ions in a material is first presented. Next, the electronic stopping power and the energy loss, the polarization force, and the coulomb explosion under cluster-ion impact are described in the dielectric function form. Alignment and structure effects are stressed. As a large and highly symmetric cluster, the electronic stopping power and the average charge are shown for a C60 cluster ion moving inside a solid. Throughout the paper, it is emphasized that the vicinage effect originating from correlation on spatial structure and orientation of constituent ions plays the key role. Moreover, results obtained in cluster production and penetration phenomena are mostly different from multiplication of those under single-ion impact.
A Novel Predictive Model for Hospital Survival in Patients who are Critically Ill with Dialysis-Dependent AKI: A Retrospective Single-Center Exploratory Study
Authors: Ganguli Anirban , Farooq Saad , Desai Neerja , Adhikari Shreedhar , Shah Vatsal , Sherman Michael J. , Veis Judith H. , Moore Jack 
Published: January 2022

Background
Mortality of patients who are critically ill with AKI initiated on RRT is very high. Identifying modifiable and unmodifiable clinical variables at dialysis start that are associated with hospital survival can help, not only in prognostication, but also in clinical triaging.

Methods
A retrospective observational study was conducted on patients with AKI-D who were initiated on RRT in the medical and surgical intensive care units (ICUs) of a high-acuity academic medical center from January 2010 through December 2015. We excluded patients with suspected poisoning, ESKD, stage 5 CKD not on dialysis, or patients with AKI-D initiated on RRT outside of the ICU setting. The primary outcome was in-hospital mortality.

Results
Of the 416 patients who were critically ill with AKI-D admitted to the medical (38%), surgical (41%), and cardiac (21%) ICUs, with nearly 75% on artificial organ support, the mean age 62.1±14.8 years, mean SOFA score was 11.8±4.3, dialysis was initiated using continuous RRT in 261 (63%) and intermittent hemodialysis in 155 (37%) patients. Incidence of survival to hospital discharge was 48%. Using multivariable logistic regression with stepwise backward elimination, a prognostic model was created that included the variables age, CKD, COPD, admission, and within 24 hours of the start SOFA score, refractory hyperkalemia and uremic encephalopathy as dialysis indications, BUN >100 mg/dl, serum creatinine, serum lactate, serum albumin, CRRT as initial modality, severe volume overload, and abdominal surgery. The model exhibited good calibration (goodness of fit test, P=0.83) and excellent discrimination (optimism-corrected C statistic 0.93).

Conclusions
In this single-center, diverse, critically ill AKI-D population, a novel prognostic model that combined widely used ICU scores, clinical and biochemical data at dialysis start, and dialysis indication and modality, robustly predicted short-term survival. External validation is needed to prove the generalizability of the study findings.
Review of research on salt-affected soils in the Debrecen agricultural high educational institutions, with special focus on the mapping of Hortobágy
Authors: Tóth Tibor , Pásztor László , Árvai Mátyás , Sipos György , Takács Katalin , Rékasi Márk , Szatmári Gábor , Balog Kitti , Kovács Zsófia Adrienn 
Published: January 2022

The history of the research of Debrecen scholars on salt-affected soils of Hortobágy and the region is very rich and diverse. Focusing on mapping, the following stages can be distinguished, indicating the completeness of the maps and the purpose of the performed work− First, quantitative maps (Arany, 1926) for the utilization of the lands at 1:75,000 (Figure 1).− Second, quantitative map (Kreybig, 1943) for the utilization of the lands at 1:25,000.− Third, category map (Kreybig et al., 1935) testing the suitability of the classification system at :75,000.− Fourth, partial category map (Szabolcs, 1954), showing the reasons of unsuccessful management at 1:10,000.− Fifth, partial quantitative map (Csillag et al., 1996), showing the utility of digital sampling at 1:25,000.− Sixth, partial quantitative map (Tamás and Lénárt, 2006), showing the capacity of multispectral remote imagery at 1:100.− Seventh, partial quantitative map (Douaik et al., 2006), showing the usefulness of geostatistical mapping at 1:10,000.− Eight, national quantitative maps (Pásztor et al., 2016), showing the applicability of geostatistics for administrative purposes at 1:10,000.− Ninth, partial quantitative/category map (authors, 2019), finding the optimal methods at 1:10,000.
Проривні технології в оборонній сфері України
Authors: Слюсар Вадим Іванович , Сотник Владислав Віталійович , Купчин Артем Валерійович , Шостак Владислав Григорович 
Published: January 2022

Основним месседжем написання цієї статті є формування наукового зацікавлення на предмет ідентифікації проривних технологій, як суттєвого інструменту зміцнення технологічної безпеки країни.
У роботі описано досвід НАТО щодо визначення переліку проривних технологій. Визначені спільні та відмінні риси критичних та проривних технологій. Обґрунтовано актуальність та необхідність створення одного уніфікованогопереліку критичних і проривних технологій.
Запропоновано дефініцію критичних і проривних технологій в оборонній сфері, а також новий концептуальний підхід щодо їх структурування.
Опрацьовано методику формування переліку критичних і проривних технологій на основі нечіткої логіки. Визначено математично обґрунтовані межі ідентифікації технології як критичної або проривної.