bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of extensive artery isolation during robotic-assisted partial nephrectomy on blood pressure of patients with poorly controlled hypertension: a preliminary study
Authors: Wang Xin , Zhao Xiaozhi , Ji ChangWei , Liu Guangxiang , Li Xiaogong , Guo Hongqian 
Published: October 2022

Abstract
Purpose
To investigate whether extensive renal artery isolation during robotic-assisted partial nephrectomy (RAPN) for renal cell carcinoma (RCC) affects blood pressure (BP) of patients with poorly controlled hypertension.

Methods
We included 60 patients diagnosed with poorly controlled hypertension who underwent RAPN by an experienced surgeon. The renal artery of the treated kidney was sufficiently isolated. Systolic BP (SBP), diastolic BP (DBP) and antihypertensive medication information were obtained at baseline and 3- and 6-month follow-up after surgery. Primary endpoints were changes in BP, and medications. Predictors of SBP reduction at 3 months were assessed by multivariable logistic regression.

Results
All 60 RAPN procedures were successful, with no major intra- or postoperative complications. Mean SBP and DBP decreased significantly at 3 months after surgery (SBP, −7.8 ± 6.3 mmHg, P < 0.001; DBP, −4.2 ± 6.4 mmHg, P = 0.01). SBP and DBP did not differ between 3- and 6-month follow-up. The mean number of BP medications prescribed was lower at 3 months than baseline (1.7 ± 1.0 vs 2.1 ± 1.0, P = 0.016). The only significant predictor of SBP reduction at 3 months was baseline SBP.

Conclusions
Renal denervation with extensive renal artery isolation during RAPN may improve BP control among patients with poorly controlled hypertension in short term.
Filling the gap between the heart and the body in acromegaly: a case-control study
Authors: Ságová Ivana , Dragula Milan , Mokáň Marián , Vaňuga Peter 
Published: October 2022

Abstract
Objective
Cardiovascul diseases are the most common comorbidities in acromegaly. Potential parameters in pathology of cardiovascular comorbidities are changes in levels of growth hormone (GH) and insulin-like growth factor 1 (IGF-1) as well as body composition parameters.

Purpose
The aim of this study was to examine morphological and functional parameters of the cardiovascular system by echocardiography and to assess its relationship with disease activity and body composition parameters.

Methods
We prospectively enroled 129 acromegalic patients (82 females, 47 males) and 80 healthy controls (53 females, 27 males) matched for age, gender, and BMI. All patients underwent two-dimensional echocardiography. Body composition parameters were assessed by dual-energy X-ray absorptiometry.

Results
Acromegaly patients presented with higher left ventricle mass (LVM) compared to controls (LVMI: 123 ± 45 g/m2 vs 83 ± 16 g/m2, P < 0.001). Prevalence of left ventricle hypertrophy in acromegaly patients was 67% (78% concentric, 22% eccentric). IGF -1 levels, BMI, and lean mass positively correlated with LVM in all acromegaly patients (P < 0.001). Fat mass positively correlated with LVM in females (R = 0.306, P = 0.005), but this correlation was not found in males. We did not find any difference in size of the left and right ventricle between acromegaly patients and controls. Acromegaly patients presented with left atrium enlargement, diastolic dysfunction and low incidence of systolic dysfunction. Valvopathy was found in 43% of patients with predominant (31%) prevalence of mitral regurgitation.

Conclusion
Our study demonstrates higher prevalence of cardiovascular comorbidities in acromegaly patients and the impact of IGF-1 levels and body composition parameters in pathology in some of these comorbidities.
Populus alba cationic cell-wall-bound peroxidase (CWPO-C) regulates the plant growth and affects auxin concentration in Arabidopsis thaliana
Authors: Yoshikay-Benitez Diego Alonso , Yokoyama Yusuke , Ohira Kaori , Fujita Koki , Tomiie Azusa , Kijidani Yoshio , Shigeto Jun , Tsutsumi Yuji 
Published: October 2022

AbstractThe poplar cationic cell-wall-bound peroxidase (CWPO-C) mediates the oxidative polymerization of lignin precursors, especially sinapyl alcohols, and high molecular weight compounds that cannot be oxidized by other plant peroxidases, including horseradish peroxidase C. Therefore, CWPO-C is believed to be a lignification-specific peroxidase, but direct evidence of its function is lacking. Thus, the CWPO-C expression pattern in Arabidopsis thaliana (Arabidopsis) was determined using the β-glucuronidase gene as a reporter. Our data indicated that CWPO-C was expressed in young organs, including the meristem, leaf, root, flower, and young xylem in the upper part of the stem. Compared with the wild-type control, transgenic Arabidopsis plants overexpressing CWPO-C had shorter stems. Approximately 60% of the plants in the transgenic line with the highest CWPO-C content had curled stems. These results indicate that CWPO-C plays a role in cell elongation. When plants were placed horizontally, induced CWPO-C expression was detected in the curved part of the stem during the gravitropic response. The stem curvature associated with gravitropism is controlled by auxin localization. The time needed for Arabidopsis plants overexpressing CWPO-C placed horizontally to bend by 90° was almost double the time required for the similarly treated wild-type controls. Moreover, the auxin content was significantly lower in the CWPO-C-overexpressing plants than in the wild-type plants. These results strongly suggest that CWPO-C has pleiotropic effects on plant growth and indole-3-acetic acid (IAA) accumulation. These effects may be mediated by altered IAA concentration due to oxidation.
A Program for Developing Some Motor Skills for Down Syndrome Children Using Music
Authors: Mazeed Huda M. 
Published: October 2022

AbstractThe current study presents a rhythmic music program to acquire some motor skills for children with Down syndrome. The research sample was taken from one of the specialized Down syndrome learning centers for children, and the sample was taken in a random manner. The sample of children consisted of 20 boys and girls and divided into experimental and control groups. The researcher also prepared a list of the appropriate motor skills for these children (walking, running, jumping, throwing), in addition to the motor skills scale to determine the effectiveness of the proposed program. The results were statistically analyzed using the analysis of covariance, where pre-test serving as a covariate. The results indicated an improvement in the performance of all motor activities under study for the children of the experimental group compared to the control group, and this confirms the extent of the positive impact of the musical rhythmic program for these children, which affects the children positively in the performance of their motor.
Delayed gastric emptying is associated with increased risk of mortality in patients undergoing pancreaticoduodenectomy for pancreatic adenocarcinoma
Authors: Dominguez Oscar Hernandez , Grigorian Areg , Wolf Ronald F. , Imagawa David K. , Nahmias Jeffry T. , Jutric Zeljka 
Published: October 2022

AbstractDelayed gastric emptying (DGE) is common in patients undergoing pancreaticoduodenectomy (PD). The effect of DGE on mortality is less clear. We sought to identify predictors of mortality in patients undergoing PD for pancreatic adenocarcinoma hypothesizing DGE to independently increase risk of 30-day mortality. The ACS-NSQIP targeted pancreatectomy database (2014–2017) was queried for patients with pancreatic adenocarcinoma undergoing PD. A multivariable logistic regression analysis was performed. Separate sensitivity analyses were performed adjusting for postoperative pancreatic fistula (POPF) grades A–C. Out of 8011 patients undergoing PD, 1246 had DGE (15.6%). About 8.5% of patients with DGE had no oral intake by postoperative day-14. The DGE group had a longer median operative duration (373 vs. 362 min, p = 0.019), and a longer hospital length of stay (16.5 vs. 8 days, p < 0.001). After adjusting for age, gender, comorbidities, preoperative chemotherapy, preoperative radiation, open versus laparoscopic approach, vascular resection, deep surgical space infection (DSSI), postoperative percutaneous drain placement, and development of a POPF, DGE was associated with an increased risk for 30-day mortality (OR 3.25, 2.16–4.88, p < 0.001). On sub-analysis, grades A and B POPF were not associated with risk of mortality while grade C POPF was associated with increased risk of mortality (OR 5.64, 2.24–14.17, p < 0.001). The rate of DGE in patients undergoing PD in this large database was over 15%. DGE is associated with greater than three times the increased associated risk of mortality, even when controlling for POPF, DSSI, and other known predictors of mortality.
Implementation of a patient blood management in an Italian City Hospital: is it effective in reducing the use of red blood cells?
Authors: Ercolani Giorgio , Solaini Leonardo , D’Acapito Fabrizio , Isopi Claudio , Pacilio Carlo Alberto , Moretti Cinzia , Agostini Vanessa , Cucchetti Alessandro 
Published: October 2022

AbstractTo evaluate the effect of patient blood management (PBM) since its introduction, we analyzed the need for transfusion and the outcomes in patients undergoing abdominal surgery for different types of tumor pre- and post-PBM. Patients undergoing elective gastric, liver, pancreatic, and colorectal surgery between 2017 and 2020 were included. The implementation of the PBM program was completed on May 1, 2018. The patients were grouped as follows: those who underwent surgery before the implementation of the program (pre-PBM) versus after the implementation (post-PBM). A total of 1302 patients were included in the analysis (445 pre-PBM vs. 857 post-PBM). The number of transfused patients per year decreased significantly after the introduction of PBM. A strong tendency for a decreased incidence of transfusion was evident in gastric and pancreatic surgery and a similar decrease was statistically significant in liver surgery. With regard to gastric surgery, a single-unit transfusion scheme was used more frequently in the post-PBM group (7.7% vs. 55% after PBM; p = 0.049); this was similar in liver surgery (17.6% vs. 58.3% after PBM; p = 0.04). Within the subgroup of patients undergoing liver surgery, a significant reduction in the use of blood transfusion (20.5% vs. 6.7%; p = 0.002) and a decrease in the Hb trigger for transfusion (8.5, 8.2–9.5 vs. 8.2, 7.7–8.4 g/dl; p = 0.039) was reported after the PBM introduction. After the implementation of a PBM protocol, a significant reduction in the number of patients receiving blood transfusion was demonstrated, with a strong tendency to minimize the use of blood products for most types of oncologic surgery.
Avoidant-restrictive food intake disorder in a male patient with Goldenhar syndrome
Authors: Bergonzini Luca , Pruccoli Jacopo , Parmeggiani Antonia 
Published: October 2022

Abstract
Background
Goldenhar syndrome (GS) is a rare congenital condition characterized by the underdevelopment of structures deriving from the first and second branchial arches. Clinical phenotype might encompass extra-craniofacial abnormalities, and patients may experience neuropsychiatric disorders with a higher prevalence than healthy controls. To the best of our knowledge, an association between GS and Feeding and Eating Disorders (FED) has never been reported in the literature.

Case report
A 15-year-old boy with GS was referred to our outpatient clinic due to severe underweight (BMI of 12.7 kg/m2) and food intake disorder with avoidant restrictive features. After a diagnosis of avoidant-restrictive food intake disorder (ARFID) was made, an inpatient multidisciplinary intervention and outpatient follow-up program were provided, which resulted in the improvement of the boy’s weight and FED psychopathology.

Conclusions
The current report describes the first case of a young male with GS and ARFID. We suggest that ARFID may present itself as part of the spectrum of neuropsychiatric disorders associated with the syndrome; since traumatic experiences and gastrointestinal discomfort play a pivotal role in the development of ARFID among children, attention should be paid to those affected by GS that involves crucial structures in the swallowing process. Further literature evidence will help portray the complex relationship between ARFID and GS more precisely.

Level of evidence
Level V, case report.
An automatic inversion approach for magnetic data applying the global bat optimization algorithm (GBOA): application to ore deposits and basement rock intrusion
Authors: Essa Khalid S. , Diab Zein E. 
Published: October 2022

Abstract
Recently, metaheuristic approaches are frequently used to the potential data inversion (i.e., magnetic data) as a global optimizing approach. In the present study, we proposed a global optimizing bat algorithm (GOBA) that based on bat echolocation behavior to obtain globally optimal solutions (best parameters) of magnetic anomalies. The best determined source parameters were picked at the suggested minimum objective function. The proposed GOBA approach does not require prior information and represents an effective technique of surveying the entire domain of the raw data to evaluate sources optimal parameters. The GOBA approach is employed to magnetic data profiles to determine the characteristic source attributes (i.e. the vertical depths to the center of the anomalous structures, the magnitude of amplitude coefficients, the sources origin, the approximated geometric form factors, and the effective angles of magnetization). The GOBA approach can be applied to single and multiple anomaly structures in the restricted categories of basic geometric shapes (spheres, cylinders, sheets, and dikes). The stability, constancy, and performance of the given GOBA approach are achieved on different purely and contaminated examples for individual and double sources. Besides, the introduced GOBA approach has been fruitfully utilized to three field datasets from Turkey, Canada, and Senegal for ore deposit and basement rock intrusion investigations. Overall, the recovered inversion results from the GOBA approach are in high correlation with the available drill-holes, geologic data, and scholarly articles outcomes. Finally, the provided metaheuristic GOBA approach is a simple, accurate, and powerful technique for magnetic data interpretation.

Article highlights

An automatic approach for magnetic data interpretation to investigate the ore deposits and sustainable resources such as volcanic and basement rock intrusions based on bat echolocation behavior to obtain the global optimal solutions.

In this study we built 2D models aims to image of the interior of the subsurface to investigate their natural resources, for example minerals & ore deposits and rock intrusions, helping in understand their concentration and the distribution location, including the depth to their sources.

We came to the conclusion that the suggested approach is useful in ore & mineral research, the reconnaissance geological studies and can be extend to the volcanic activity & geothermal exploration studies in the future.
A Multi-level Mesh Mutual Attention Model for Visual Question Answering
Authors: Lei Zhi , Zhang Guixian , Wu Lijuan , Zhang Kui , Liang Rongjiao 
Published: October 2022

AbstractVisual question answering is a complex multimodal task involving images and text, with broad application prospects in human–computer interaction and medical assistance. Therefore, how to deal with the feature interaction and multimodal feature fusion between the critical regions in the image and the keywords in the question is an important issue. To this end, we propose a neural network based on the encoder–decoder structure of the transformer architecture. Specifically, in the encoder, we use multi-head self-attention to mine word–word connections within question features and stack multiple layers of attention to obtain multi-level question features. We propose a mutual attention module to perform information exchange between modalities for better question features and image features representation on the decoder side. Besides, we connect the encoder and decoder in a meshed manner, perform mutual attention operations with multi-level question features, and aggregate information in an adaptive way. We propose a multi-scale fusion module in the fusion stage, which utilizes feature information at different scales to complete modal fusion. We test and validate the model effectiveness on VQA v1 and VQA v2 datasets. Our model achieves better results than state-of-the-art methods.
Training Teachers to Teach Probability: A Promising Research Area
Authors: Batanero Carmen 
Published: October 2022

AbstractIn this commentary, I reflect on the relevant role that the education of teachers imply to assure a successful teaching of probability at school levels. Unfortunately, research on this issue is still scarce. In this sense, the four papers included in this section are welcome because they approach this research problem from different perspectives. I analyse these perspectives using the Didactic-Mathematics Knowledge and Competences Model (CCDM) developed at the University of Granada, Spain.
Art and Environmental Struggle Curating an Exhibition About Place‐Rooted Ecological Knowledge
Authors: Avril Ellen , Weislogel Andrew C. , Frankel Kate Addleman , Yearsley Elizabeth , Chu Jumay 
Published: October 2022

AbstractInspired by ecological calendars, the Herbert F. Johnson Museum of Art organized the exhibition Art and Environmental Struggle to coincide with the international conference Rhythms of the Land: Indigenous Knowledge, Science, and Thriving Together in a Changing Climate, held at Cornell University in October 2021. The exhibition emphasized Indigenous ways of knowing and deployed the works of lesser‐known artists from around the world to build greater understanding of and empathy for their communities' often overlooked histories and perspectives. A collaboration of three Johnson Museum curators and an expert on global Indigenous art, the exhibition presented 20 works by artists responding to environmental challenges occurring in their countries and communities and was conceived as part of the program of conference events that culminated in the dance, music, and video work Blood, Water, Earth created and performed by Santee Smith. Emphasizing impacts of colonialism, neocolonialism, geopolitical forces, and industries, the artworks reveal the consequences of environmental damage on the food production, security, cultural independence, and general well‐being of communities who have contributed the least to the current crisis but feel its effects most acutely. The concept of struggle for environmental justice binds together all the visual artists represented in Art and Environmental Struggle. When viewed in the context of the ecological calendar model, the compelling ways in which visual and performing artists confront these topics through an expression of Indigenous ecological knowledge, environmental stewardship, and place‐rooted traditions, present a diverse but resilient perspective and offer a methodology of hope to address this most pressing of issues.
Integrated Dynamics‐Physics Coupling for Weather to Climate Models: GFDL SHiELD With In‐Line Microphysics
Authors: Zhou Linjiong , Harris Lucas 
Published: November 2022

AbstractWe propose an integrated dynamics‐physics coupling framework for weather and climate‐scale models. Each physical parameterization would be advanced on its natural time scale, revise the thermodynamics to include moist effects, and finally integrated into the relevant components of the dynamical core. We show results using a cloud microphysics scheme integrated within the dynamical core of the Geophysical Fluid Dynamics Laboratory System for High‐resolution prediction on Earth‐to‐Local Domains weather model to demonstrate the promise of this concept. We call it the in‐line microphysics as it is in‐lined within the dynamical core. Statistics gathered from 1 year of weather forecasts show significantly better prediction skills when the model is upgraded to use the in‐line microphysics. However, we do find that some biases are degraded with the in‐line microphysics. The in‐line microphysics also shows larger‐amplitude and higher‐frequency variations in cloud structures within a tropical cyclone than the traditionally‐coupled microphysics. Finally, we discuss the prospects for further development of this integrated dynamics‐physics coupling.
Influence of Planetary Surface Temperature on the Tectonic Transition From Heat Pipes
Authors: Basu Sarkar Debajyoti , Moore William B. 
Published: November 2022

AbstractHeat transport from the interior to the surface of a terrestrial body dictates the deformation experienced by the lithosphere. Terrestrial bodies with high internal heating rates exhibit heat‐pipe volcanism because subsolidus convection within the mantle has a limit to the amount of heat it can transport without extensive melting. Using numerical simulations, we investigate the lithospheric deformation associated with the global‐scale volcanism on such bodies. Specifically, we study the role of surface temperature and activation energy of mantle rocks while analyzing and characterizing this global deformation—as a terrestrial planet transitions out of heat pipes. We find that increased surface temperature extends the duration of heat‐pipe volcanism, and plate tectonics highly depends on the temperature sensitivity of mantle viscosity. Our findings suggest that a terrestrial planet with a hot surface will develop a thick lithosphere, and thus transition into a stagnant lid tectonic regime following heat pipes.
Laboratory Investigation of Hydraulic Fracture Growth in Zimbabwe Gabbro
Authors: Liu Dong , Lecampion Brice 
Published: October 2022

AbstractDirect measurement of the apparent toughness evolution during hydraulic fracture growth remains challenging in rocks due to the difficulty of measuring the time evolution of the fracture geometry. We report hydraulic fracturing tests performed in 250 × 250 × 250 mm Zimbabwe gabbro under different confining stress. Using time‐lapse active acoustic surveys, we reconstruct the fracture front and fracture width using scattered and transmitted waves. After verifying that hydraulic fracture growth is dominated by the energy dissipated in fracture creation such that the fluid pressure can be considered spatially uniform in the fracture (negligible viscous flow energy dissipation), we estimate the apparent fracture toughness, using the theory of linear hydraulic fracture mechanics, by combining fracture geometry and pressure data. The apparent fracture energy is higher than that measured from semicircular bending tests. The created fractures evolve in a planar and radial geometry at the macroscopic scale, but we observe overlapping segments and bridges at the millimetric scale. This complex segmentation at a scale on par with the rock grain size is likely responsible for the observed higher fracture energy at centimetric scale. Such fracture segmentation and bridging will necessarily occur when encountering heterogeneities and result in a further increase of fracture energy at a larger scale even if the overall macroscopic geometry remains planar. The experimental data set reported here should guide modeling efforts necessary to better predict hydraulic fracture growth in rock masses.