bluuebunny/crossref_metadata_2025_split huggingface dataset:
In Situ Synthesis of Multivariate Zeolitic Imidazolate Frameworks for C2H4/C2H6 Kinetic Separation
Authors: Nam Ki Jin , Yu Hyun Jung , Yu Seungho , Seong Jeongho , Kim Seok‐Jhin , Kim Ki Chul , Lee Jong Suk 
Published: September 2022

AbstractHerein, a new approach for the in situ synthesis of zeolitic imidazolate framework (ZIF) nanoparticles with triple ligands, referred to as Sogang ZIF‐8 (SZIF‐8), is reported for enhanced C2H4/C2H6 kinetic separation. SZIF‐8 consists of tetrahedral zinc metals coordinated with tri‐butyl amine (TBA), 2,4‐dimethylimidazole (DIm), and 2‐methylimidazole (MIm). SZIF‐8(x) with different DIm contents in x (up to 23.2 mol%) are synthesized in situ because TBA preferably deprotonates DIm ligands due to the much lower pKa of DIm over MIm, allowing for the Zn‐DIm coordination. The Zn‐DIm coordination reduces the window size of ZIF‐8 with suppressed linker flipping motion due to bulky DIm ligands and simultaneously enhances the interfacial interaction between 6FDA‐DAM polyimide (6FDA) and SZIF‐8 via electron donor–acceptor interactions. Consequently, 6FDA/SZIF‐8(13) mixed matrix membrane exhibits an excellent C2H4 permeability of 60.3 Barrer and C2H4/C2H6 selectivity of 4.5. The temperature‐dependent transport characterization reveals that such excellent C2H4/C2H6 kinetic separation is attained by the enhancement in size discrimination‐based energetic selectivity. Our hybrid multi‐ligand approach can offer a useful tool for the fine‐tuning of molecular structures and textural properties of other metal organic frameworks.
Changes in tear production in a dog with keratoconjunctivitis sicca for a year after inevitable nictitating membrane gland resection due to suspicion of a malignant tumour
Authors: Yoon Hyun‐Jeong , Kim Joon‐Young 
Published: September 2022

AbstractSince the removal of the NM causes KCS in dogs, it was contraindicated to remove the NM unless unavoidable such as in a malignant tumour. However, to the best of author's knowledge, there are no reports of conjunctivitis and keratitis owing to decreased tear production following removal of the NM gland. This case study demonstrates the tear production changes in a dog for a year after removal of the nictitating membrane (NM) due to suspicion of a malignant tumour. A 13‐year‐old spayed female English Cocker Spaniel who had suffered from severe ocular discharge, discomfort, keratoconjunctivitis sicca (KCS), and NM enlargement in the right eye was brought to our hospital. The dog could not tolerate treatment with topical 0.2% cyclosporine or corticosteroids. The dog's right eye had NM gland prolapse, severe follicular conjunctivitis and a very low Schirmer tear test‐1 (STT‐1) value of 3 mm/min. Furthermore, the result of fine needle aspiration of the enlarged NM gland suggested a risk of malignancy. Despite the risk of KCS, complete NM resection was performed to diagnose the tumour. Fortunately, the final histopathological evaluation revealed chronic inflammation without any evidence of malignancy. Contrary to concerns that the STT‐1 value would further decrease after the removal of the NM gland, the STT‐1 value remained elevated compared to that before surgery, and the clinical symptoms improved for a year. It is generally known that NM gland resection is not recommended due to the risk of developing iatrogenic KCS unless a malignant tumour is suspected. In this case, surgical removal of the inflammatory NM gland that was not responsive to medications had a positive effect on KCS. Since the inflammatory and structural disease of the NM was strengthening KCS, the outcome was thought to be different from that when the normal third eyelid was removed.
Pyoderma caused by Proteus mirabilis in sheep
Authors: Abdollahi Mostafa , Javan Ashkan Jebelli , Shokrpoor Sara , Beidokhtinezhad Mohammadhesam , Tamai Iraj Ashrafi 
Published: September 2022

AbstractPyoderma is a purulent skin infection usually caused by bacteria and can be divided into primary and secondary categories based on histology. In the present study, an 18‐month‐old female mixed breed sheep was examined for pyoderma at the injection site of the enterotoxemia vaccine. After routine bacteriology and histopathology procedures, secondary pyoderma caused by Proteus mirabilis was diagnosed. The bacterium analysed using genome sequencing and new strain called AJJ 2021 was diagnosed. This is the first report of pyoderma caused by Proteus mirabilis in sheep.
A case of extraosseous intradural osteosarcoma of the spine in a dog
Authors: Riggers Denise Sarina , Rosati Marco , Köhler Claudia , Matiasek Kaspar , Loderstedt Shenja 
Published: September 2022

AbstractA 9.5‐year‐old labrador presented with signs of progressive C1–C5 myelopathy. Magnetic resonance imaging of the cervical spine revealed a broad‐based, jagged and partially ill‐defined intradural mass lesion at the level of C3–C4 cervical vertebra. Decompressive spinal surgery was performed and the removed mass was sent for histopathological examination that identified an intradural extraosseous osteosarcoma. This very rare canine spinal tumour appears to arise predominantly in the cervical spine and occurs with no predisposing factors. It should be considered as a differential diagnosis for spinal tumours.
What benefits are the most important to you, your community, and society? Perception of ecosystem services provided by nature‐based solutions
Authors: Hekrle Marek 
Published: September 2022

AbstractEcosystem services (ES) provided by nature‐based solutions (NBS) have been examined using various data collection techniques and preference elicitation methods to understand what ES are important to human well‐being. This article provides a systematic review of 153 scientific publications, with a focus on data collection techniques and perspectives of well‐being used when eliciting preferences toward multiple ES provided by NBS. ES provided by urban parks, urban trees, and community gardens are the most commonly examined; however, generally specified NBS such as “green spaces” or “green infrastructure” prevail. The review further shows that the questionnaire surveys is the dominant technique for bringing evidence about the most preferred ES, followed by semi‐structured interviews and workshops. Only a limited number of studies use revealed or stated preference methods as a part of data collection efforts such as a choice experiment or contingent valuation. Additionally, the review defines three different perspectives of well‐being considered but rarely discussed in existing studies: individual; community; and society well‐being perspectives. As the concept of well‐being is hardly discussed in NBS literature and still depends on a large degree of subjectivity, this review highlights the need for future research that looks more deeply at individual, community, and social well‐being, which is influenced differently by the implementation of NBS.This article is categorized under:
Water and Life > Conservation, Management, and Awareness
Water and Life > Methods
Removal of hydroxychloroquine from an aqueous solution using living microalgae: Effect of operating parameters on removal efficiency and mechanisms
Authors: El Amri Radouane , Elkacmi Reda , Hasib Aziz , Boudouch Otmane 
Published: September 2022

AbstractWastewater contaminated with hydroxychloroquine (HCQ) poses a serious threat to the environment and human life. This study aimed to evaluate the ability of living microalgae to remove HCQ from an aqueous solution. Batch mode experiments were conducted under different conditions to investigate the effect of operating parameters on HCQ removal efficiency and mechanisms. Equilibrium, kinetic and thermodynamic study was also carried out to better describe the interactions between HCQ and microalgae. The maximum HCQ removal was 92.10 ± 1.25% obtained under optimal pH of 9.9 ± 0.1, a contact time of 45 min, a stirring speed of 300 rpm, an initial HCQ concentration of 20 mg/L, and a microalgae dose of 100 mg/L. The Langmuir isotherm and the pseudo‐second‐order kinetic model were best suited for the biosorption experiments, and the maximum biosorption capacity was 339.02 mg/g. The thermodynamic study showed that the biosorption process was exothermic and spontaneous. Experiments on real wastewater showed that the HCQ removal was not significantly affected by the presence of other contaminants in the water.Practitioner Points

The best HCQ removal was 92.10 ± 1.25% obtained under optimal conditions.
The Langmuir isotherm and the pseudo‐second‐order kinetic model were best suited for the biosorption experiments.
The maximum biosorption capacity was 339.02 mg/g.
The thermodynamic study showed that the biosorption process was exothermic and spontaneous.
The microalgae studied can be successfully used in HCQ removal from water.
Athena synergies in the multi-messenger and transient universe
Authors: Piro Luigi , Ahlers Markus , Coleiro Alexis , Colpi Monica , de Oña Wilhelmi Emma , Guainazzi Matteo , Jonker Peter G. , Namara Paul Mc , Nichols David A. , O’Brien Paul , Troja Eleonora , Vink Jacco , Aird James , Amati Lorenzo , Anand Shreya , Bozzo Enrico , Carrera Francisco J. , Fabian Andrew C. , Fryer Christopher , Hall Evan , Korobkin Oleg , Korol Valeriya , Mangiagli Alberto , Martínez-Núñez Silvia , Nissanke Samaya , Osborne Julien , Padovani Paolo , Rossi Elena M. , Ryan Geoffrey , Sesana Alberto , Stratta Giulia , Tanvir Niel , van Eerten Hendrik 
Published: September 2022

AbstractIn this paper we explore the scientific synergies between Athena and some of the key multi-messenger facilities that should be operative concurrently with Athena. These facilities include LIGO A+, Advanced Virgo+ and future detectors for ground-based observation of gravitational waves (GW), LISA for space-based observations of GW, IceCube and KM3NeT for neutrino observations, and CTA for very high energy observations. These science themes encompass pressing issues in astrophysics, cosmology and fundamental physics such as: the central engine and jet physics in compact binary mergers, accretion processes and jet physics in Super-Massive Binary Black Holes (SMBBHs) and in compact stellar binaries, the equation of state of neutron stars, cosmic accelerators and the origin of Cosmic Rays (CRs), the origin of intermediate and high-Z elements in the Universe, the Cosmic distance scale and tests of General Relativity and the Standard Model. Observational strategies for implementing the identified science topics are also discussed. A significant part of the sources targeted by multi-messenger facilities is of transient nature. We have thus also discussed the synergy of Athena with wide-field high-energy facilities, taking THESEUS as a case study for transient discovery. This discussion covers all the Athena science goals that rely on follow-up observations of high-energy transients identified by external observatories, and includes also topics that are not based on multi-messenger observations, such as the search for missing baryons or the observation of early star populations and metal enrichment at the cosmic dawn with Gamma-Ray Bursts (GRBs).
Increases in Circulating Cortisol during the COVID-19 Pandemic are Associated with Changes in Perceived Positive and Negative Affect among Adolescents
Authors: Taylor Brittany K. , Fung Madison H. , Frenzel Michaela R. , Johnson Hallie J. , Willett Madelyn P. , Badura-Brack Amy S. , White Stuart F. , Wilson Tony W. 
Published: September 2022

AbstractThe Coronavirus Disease 2019 (COVID-19) pandemic has spread across the world and resulted in over 5 million deaths to date, as well as countless lockdowns, disruptions to daily life, and extended period of social distancing and isolation. The impacts on youth in particular are astounding, with shifts in learning platforms, limited social outlets, and prolonged uncertainty about the future. Surveys have shown that mental health among youth has severely suffered during the pandemic. However, limited research to date has reported on physiological indices of stress surrounding the pandemic, such as cortisol. Cortisol is a stress hormone that typically increases during stressful situations and can have deleterious effects on mental and physical health when chronically heightened. The present study leveraged hair cortisol concentration measurements, which allowed the retrospectiveinvestigation of circulating cortisol prior to- versus after pandemic-related local lockdowns during the first wave of the pandemic. A final sample of 44 youth ages 10- to 18-years-old provided hair samples and reported on their perceived affective well-being and level of concern regarding pandemic-related stressors between May and June of 2020. We found significant levels of concern and decreases in affective well-being following local lockdowns. Moreover, we saw that cortisol robustly increased following local lockdowns, and those increases were predictive of changes in affect. These findings provide critical insights into the underlying neuroendocrinology of stress during the pandemic and support the need for resources to support youths’ mental health and well-being during this globally significant event.
Synthesis, Characterization, and Application of BaTiO3 Nanoparticles for Anti-Cancer Activity
Authors: Fakhar-e-Alam M. , Saddique Samira , Hossain Nazia , Shahzad Aamir , Ullah Inaam , Sohail Amjad , Khan Muhammad Junaid Iqbal , Saadullah Malik 
Published: September 2022

AbstractBarium titanate (BaTiO3) nanoparticles (BTNPs) have been considered as emerging materials in biomedical sector through last decades due to the excellent physicochemical properties such as dielectric and piezoelectric structures, biocompatibility, and nonlinear optical characteristics. In this study, BTNPs were synthesized via the co-precipitation method using barium carbonate and titanium dioxide by stirring for 5 h. Then, it was annealed at 850 °C for 5 h with five different concentrations: 0.2, 0.4, 0.6, 0.8, and 1 g/mL. The structural, morphological, and optical analyses were demonstrated by different characterization techniques such as X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray (EDX), thermogravimetric analysis (TGA), Raman, and UV–visible spectroscopy. The perovskite phase of BTNPs, an intense peak at 31.6°, was observed at the lowest concentration (0.2 g/mL), and the average crystalline size was 1.42 nm based on XRD pattern. The results have been justified by SEM and EDX. TGA demonstrated the adequate thermal stability of this material. EDX analysis confirmed the composition of Ti, Ba, and O elements. Raman peaks at 305 cm−1 and 517 cm−1 confirmed the formation of BaTiO3. UV–visible spectra presented that its’ absorbance edge shifted into visible range at 404 nm. Application of BTNPs on breast cancer cell line (MCF-7) presented significant dispersion effect at 0.2, 0.4 and 0.6 g/mL of BaTiO3. A strong toxicity rate of BaTiO3 has been observed against the MCF-7 cell line. Maximum % of cell viability loss, $$\cong$$
≅
57% was recorded at 200 µg/mL of BTNPs, and minimum % of cell viability loss was observed as 19% at 50 µg/mL of BTNPs. The results presented that a higher concentration of BTPNs dosage was more effective in inhibition of breast cancer cells. Therefore, BTNPs can be recommended as a promising nanomaterial for anti-cancer drug discovery.
Accelerating emergence: the causal (but contextual) effect of social impact accelerators on nascent for-profit social ventures
Authors: Kher Romi , Yang Shu , Newbert Scott L. 
Published: September 2022

AbstractGiven the legitimacy challenges faced by entrepreneurs, gaining access to the resources necessary to create viable new ventures is often difficult. Accordingly, scholars advocate that entrepreneurs align with high-status partners to convey that they are an accepted part of the sociocultural and organizational landscape. Although startup accelerators have been argued to play this supportive role for high-tech, high-growth ventures, it remains unclear whether they are effective at serving the needs of ventures pursuing social missions alongside business structures, or for-profit social ventures (FPSVs). To explore this issue, we examine whether social impact accelerators (SIAs), accelerators specifically designed to support FPSVs, help such ventures make the transition from mere ideas to viable organizations, a process known as emergence. To determine a causal relationship, we employ a quasi-experimental design and adopt propensity score matching with the nearest neighbor matching algorithm to study 7185 startups that applied to 383 accelerators worldwide from 2013 to 2019. By matching accepted startups to a control group of rejected startups, we find that SIAs, on average, facilitate new venture emergence, with accelerated FPSVs raising more external financing, earning more revenues, and hiring more full-time employees than their unaccelerated counterparts. These results hold when controlling for selection bias, thereby providing robust evidence for a causal relationship between acceleration and startup emergence. However, a subsequent subgroup analysis reveals that this causal effect is contingent across a breadth of “who,” “when,” and “where” contexts, highlighting the idiosyncratic differences that different startups face in the acceleration process.
Variational inference and sparsity in high-dimensional deep Gaussian mixture models
Authors: Kock Lucas , Klein Nadja , Nott David J. 
Published: September 2022

AbstractGaussian mixture models are a popular tool for model-based clustering, and mixtures of factor analyzers are Gaussian mixture models having parsimonious factor covariance structure for mixture components. There are several recent extensions of mixture of factor analyzers to deep mixtures, where the Gaussian model for the latent factors is replaced by a mixture of factor analyzers. This construction can be iterated to obtain a model with many layers. These deep models are challenging to fit, and we consider Bayesian inference using sparsity priors to further regularize the estimation. A scalable natural gradient variational inference algorithm is developed for fitting the model, and we suggest computationally efficient approaches to the architecture choice using overfitted mixtures where unnecessary components drop out in the estimation. In a number of simulated and two real examples, we demonstrate the versatility of our approach for high-dimensional problems, and demonstrate that the use of sparsity inducing priors can be helpful for obtaining improved clustering results.
Coenzyme Q10 Supplementation enhances testicular volume and hemodynamics, reproductive hormones, sperm quality, and seminal antioxidant capacity in goat bucks under summer hot humid conditions
Authors: El-Sherbiny Hossam R. , Abdelnaby Elshymaa A. , El-Shahat K. H. , Salem Noha Y. , Ramadan Eman S. , Yehia Shimaa G. , Fathi Mohamed 
Published: September 2022

Abstract
Oxidative stress (OS) is brought on by heat stress (HS), which weakens antioxidant defense and initiates OS. Since mitochondria are the primary source of reactive oxygen species (ROS), HS-mediated OS may be lessened by targeting mitochondria with particular antioxidants. The purpose of this study was to investigate the effect of oral coenzyme Q10 (CoQ10) supplementation on the reproductive performance of goat bucks under HS conditions. Ten mature bucks were randomly separated into two groups and housed in an environment with a high-temperature humidity index (THI: 88.3 to 94.8; summer season). The first group (n = 5) got the baseline diet while the second group (n = 5) received supplemental oral CoQ10 (3 mg/kg BW; CoQ10 group) daily for six weeks. Testicular blood flow parameters (TBF), testicular volume (TV) and echogenicity (TE), nitric oxide (NO), seminal alanine aminotransferase (ALT) and catalase (CAT) activities, total antioxidant capacity (TAC), malondialdehyde (MDA) content, and semen quality traits were all measured. The examinations started a week before (W-1), on the first supplementation day (W0), and weekly for eight consecutive weeks (W1-W8). There were marked (P < 0.05) increases in TBF (W3-W6) and TV, and a decrease in TE (W3-W5) in the CoQ10 group compared to the CON group. Similarly, testosterone (T) and NO levels (W3-W5) in the CoQ10 group were higher (P < 0.05) than those of the control group. The CoQ10 group demonstrated significant (P < 0.05) increases in seminal CAT (W4-W8) and TAC (W2-W6) activities and decreases in ALT (W4-W7) activity and MDA (W5-W8) concentration as compared to the control group. The CoQ10 group showed improvements (P < 0.05) at W3-W6 for sperm progressive motility, viability, and normal morphology and at W6-W8 for sperm concentration. In conclusion, oral CoQ10 supplementation improved testicular hemodynamics, testosterone production, semen quality, and antioxidant capacity in goat bucks during summer heat stress conditions.
Deglobalisierung, Rekonfiguration oder Business as Usual? COVID-19 und die Grenzen der Rückverlagerung globalisierter Produktion
Authors: Butollo Florian , Staritz Cornelia 
Published: September 2022

ZusammenfassungDie wirtschaftlichen Erschütterungen infolge der COVID-19-Pandemie scheinen die Notwendigkeit einer geografischen Restrukturierung und Rückverlagerung der Produktion zu bestärken, führten sie doch die Verwundbarkeit der globalisierten Produktionsstrukturen vor Augen. Der Beitrag geht den Auswirkungen von COVID-19 auf die Geografie globaler Produktionsnetzwerke nach. In Abgrenzung zu unterkomplexen Perspektiven auf die Globalisierung wird deren multiskalarer und politisch gestalteter Charakter hervorgehoben. Basierend auf diesen theoretischen Überlegungen und Fallstudien zur Automobil‑, Elektronik- und Bekleidungsindustrie wird gefolgert, dass die COVID-19-Pandemie nicht als Auslöser für einen allgemeinen Rückbau der globalen Fertigung interpretiert werden kann, wohl aber bereits länger anhaltende Verschiebungen hin zu multipolaren Produktions- und Konsumstrukturen verstärkt. Zwar hat das Thema der Resilienz globaler Produktionsnetzwerke eine größere Aufmerksamkeit in der strategischen Planung von Unternehmen und der Industriepolitik von Staaten erhalten. Eine verstärkte Lokalisierung und Regionalisierung von Produktionsnetzwerken ist jedoch nur eine Strategie von mehreren und wurde bis jetzt kaum implementiert. Anhaltende Störungen der Lieferketten, steigende Transportkosten und vor allem geo- und umweltpolitisch motivierte Politiken könnten aber durchaus zu einem stärkeren Re- oder Nearshoring führen. Politische Bestrebungen in diese Richtung werden jedoch limitiert durch gewachsene weltwirtschaftliche Entwicklungspfade und die mit ihnen verbundenen Kräfteverhältnisse. Im Ausblick betont der Beitrag die Notwendigkeit einer umfassenden politisch motivierten Restrukturierung globaler Produktionsnetzwerke im Kontext der dringend gebotenen sozial-ökologischen Transformation.