bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vaccine‐induced binding and neutralizing antibodies against Omicron 6 months after a homologous BNT162b2 booster
Authors: Favresse Julien , Gillot Constant , Bayart Jean‐Louis , David Clara , Simon Germain , Wauthier Loris , Closset Mélanie , Dogné Jean‐Michel , Douxfils Jonathan 
Published: September 2022

AbstractEvidence about the long‐term persistence of the booster‐mediated immunity against Omicron is mandatory for pandemic management and deployment of vaccination strategies. A total of 155 healthcare professionals (104 COVID‐19 naive and 51 with a history of SARS‐CoV‐2 infection) received a homologous BNT162b2 booster. Binding antibodies against the spike protein and neutralizing antibodies against Omicron were measured at several time points before and up to 6 months after the booster. Geometric mean titers of measured antibodies were correlated to vaccine efficacy (VE) against symptomatic disease. Compared to the highest response, a significant 10.2‐ and 11.5‐fold decrease in neutralizing titers was observed after 6 months in participants with and without history of SARS‐CoV‐2 infection. A corresponding 2.5‐ and 2.9‐fold decrease in binding antibodies was observed. The estimated T1/2 of neutralizing antibodies in participants with and without history of SARS‐CoV‐2 infection was 42 (95% confidence interval [CI]: 25–137) and 36 days (95% CI: 25–65). Estimated T1/2 were longer for binding antibodies: 168 (95% CI: 116–303) and 139 days (95% CI: 113–180), respectively. Both binding and neutralizing antibodies were strongly correlated to VE (r = 0.83 and 0.89). However, binding and neutralizing antibodies were modestly correlated, and a high proportion of subjects (36.7%) with high binding antibody titers (i.e., >8434 BAU/ml) did not have neutralizing activity. A considerable decay of the humoral response was observed 6 months after the booster, and was strongly correlated with VE. Our study also shows that commercial assays available in clinical laboratories might require adaptation to better predict neutralization in the Omicron era.
Remanence deviations in permanent magnet synchronous machines evaluated using a model order reduction approach
Authors: Kolb Johann , Müller Fabian , Hameyer Kay 
Published: September 2022

AbstractIn this article remanence deviations of a permanent magnet synchronous machine are studied with the proper orthogonal decomposition (POD). The design of experiments enables to create designs with a reduced sample size compared to full factorial designs without decreasing the stochastic significance of the remanence distributions. Next, a POD basis is created with the belonging design, that is distinctly smaller than the reference. From the POD basis the projection matrix is built to compute the flux density solutions. The machine's output is then analyzed regarding accuracy originating from numerical errors. Different parameters are evaluated and compared to the reference to appraise the accuracy of the flux density solutions, which includes the POD basis size, rotor angle step size and dimension of the reduced system. Results show, that the most influence has the dimension of the reduced system. Depending on the dimension and other parameters about one quarter of computational effort can be conserved without a significant loss in accuracy.
Efficient separation of anti‐inflammatory isolates from Polygonti rhizome by three different modes of high‐speed counter‐current chromatography
Authors: Yu Jinqian , Chen Wenxiu , Zhao Lei , Yue Tao , Yang Wencui , Wang Xiao 
Published: September 2022

Successful isolation of 15 compounds from Polygonti rhizome was obtained by an efficient technique combined with macroporous resin column chromatography pretreatment and three different modes of high‐speed counter‐current chromatography for the first time. For the pretreatment, AB‐8 resin was applied to remove the polysaccharides and enrich four different parts (samples I, II, III, and IV) by polarities. For the separation, sample I was separated by pH‐zone‐refining counter‐current chromatography and seven cycle recycling mode high‐speed counter‐current chromatography, yielding four alkaloids (1‐‐4); samples II–IV were further separated by the conventional high‐speed counter‐current chromatography, yielding seven flavonoids (5–10, 12), one steroid saponin (11), and three terpenoids (13–15). Finally, the isolates were assayed for their anti‐inflammatory activities against nitric oxide production with compounds 5, 9–10, 13 showing significant anti‐inflammatory activities, IC50 values which were 13.0, 16.2, 17.1, and 14.7 μM, respectively, while others showing moderate and weak anti‐inflammatory activities, respectively.
Tracking Occupational Voice State with a Visual Analog Scale: Voice Quality, Vocal Fatigue, and Effort
Authors: Castillo‐Allendes Adrián , Guzmán‐Ferrada Daniel , Hunter Eric J. , Fuentes‐López Eduardo 
Published: September 2022

BackgroundDue to elevated vocal health risk in industries such as call centers, there is a need to have accessible and quick self‐report tools for voice symptoms. This study aimed to determine if the concurrent and construct validity of three visual analog scales (VASs) of voice quality and symptoms could be used as a screening tool in call center agents.MethodsA cross‐sectional study was carried out in three call center companies. The Voice Handicap Index‐10 (VHI‐10) and a vocal hygiene and symptoms survey were administered to 66 call center workers. Further, acoustic parameters including harmonics‐to‐noise ratio (HNR), smoothed cepstral peak prominence (CPPs), L1‐L0 slope, and Alpha ratio were collected. Finally, workers completed three VASs capturing self‐perception of vocal effort (VAS‐1), voice quality (VAS‐2), and vocal fatigue (VAS‐3). Linear regression models with bootstrapping evaluated the possible relationship between the three VASs measurements, self‐perceived vocal symptoms, and acoustic parameters.ResultsVAS‐1 scores were associated with HNR and voice breaks, VAS‐2 with voice breaks, and VAS‐3 with Alpha ratio. Using the area under a receiver operating characteristic curve (AUC), the highest AUC for detecting an altered VHI‐10 questionnaire score was observed for the three VASs. Also, the highest AUC for detecting altered CPPs was reached for the VAS‐1.ConclusionsVAS as a self‐report instrument of vocal symptoms is related to psychosocial voice impairment and alterations of acoustic voice parameters in call center workers. Such instruments could be easily implemented to identify voice complaints in these populations.Level of Evidence2 (Diagnosis research question) Laryngoscope, 133:1676–1682, 2023
Evaluation of mechanical and tribological properties of nano clay reinforced Kevlar/Sisal polyester composites
Authors: Somaiah Chowdary Mallampati , Raghavendra Gujjala , Niranjan Kumar M. S. R. , Ojha Shakuntala , Anupama Ammulu Manne , Prasanthi P. Phani 
Published: September 2022

AbstractDue to the material's balance of mechanical and ecological features, hybrid composites have become a hot topic among researchers. Hybridization is a helpful process for improving the strength and performance of composite materials. Hybrid composites were created in this study by reinforcing Kevlar(K)/Sisal(S) in Polyester using a hand lay‐up method with various wt% (2,4,6 wt%) of Nano clay (NC) reinforcements. Mechanical experiments were performed on hybrid composite laminates to establish their tensile and flexural properties, and SEM was used to characterize the fractured samples. The fabricated specimens were also subjected to erosion tests, conducted at ambient temperature with an elongated silica sand erodent striking at 148 m/s at impingement angles of 30, 60, and 90°. In comparison to 0–4 wt% NC reinforcement, the tensile strength increased by 18% for the polyester/KSSK composites. Flexural strength is highest at 2 wt%, while polyester/KSSK reinforced NC composites have a 28% improvement in flexural strength compared to 0–2 wt%. The erosion wear resistance of 2 wt% NC reinforced KSSK/polyester was excellent in the normal direction, with minor wear at a 90° impingement angle. This conclusion supports the suggested new laminates' suitability for engineering materials in the aviation and automobile industry.
Transforming one organ into another to overcome challenges in tissue engineering
Authors: Wang Zhenzhen , Tian Xuejiao , Wang Chunming , Qi Xiaolong , Gracia‐Sancho Jordi , Dong Lei 
Published: September 2022

AbstractTissue engineering (TE) is promising for the regeneration of failed organs. However, immune rejection, shortage of seed cells, and unintegrated blood vessels restrict the development and clinical application of TE. The last factor is the most challenging and intractable. Harnessing the mature blood vessel network in existing dispensable organs could be a powerful approach to effectively overcome the obstacles. After being remodeled to harbor an immunosuppressive and proregenerative niche, these potential target organs can be transformed into other organs with specific physiological functions, compensating the latter's failed native functions. Organ transformation, such as a hepatized spleen, represents an effective and encouraging TE strategy. In this review, we discuss the current development and obstacles of TE and its feasibility and superiority in organ transformation.
Associations of autoantibodies and clinical profile of the patients with systemic sclerosis
Authors: Mahmud Shahin , Choudhury Minhaj R. , Bandhan Iftekhar H. , Islam Md. Sahidul , Shahin Md. Abu , Haq Syed A. , Zaman Mohammad M. 
Published: September 2022

AbstractBackgroundSystemic sclerosis is characterized by the involvement of organs and the presence of specific antibodies. The objectives of this study were to identify the autoantibodies and to determine their association with the selected clinical features of the disease among Bangladeshi systemic sclerosis patients.MethodsThis cross‐sectional study was performed at the rheumatology outpatient clinic of Bangabandhu Sheikh Mujib Medical University. Autoantibodies against nine systemic sclerosis‐specific antigens were tested using an enzyme‐linked immunoassay immunoblot kit. Several clinical features of patients with positive and negative autoantibody were examined by χ2 or Fisher's exact tests.ResultsA total of 71 patients with systemic sclerosis (66; 93.0% female) were included. Their mean age at disease onset was 33.2 years. Fifty‐seven (80.3%) patients had diffuse cutaneous subtype. Out of nine autoantibodies, four were positive, anti‐topoisomerase‐I (57.7%), anti‐U1 ribonucleic protein (21.1%), anti‐RNA polymerase III (18.3%), and anticentromere antibodies (4.2%). Eleven (15.5%) patients were negative for any antibodies and 11 patients were positive for at least two autoantibodies. Anti‐U3‐RNP, anti‐PM‐Scl, anti‐Ku, and anti‐Th/To auto antibodies were absent in all patients. Anti‐RNA polymerase III was associated with raised pulmonary arterial systolic pressure (PASP) and anti‐U1‐RNP with decreased forced vital capacity (FVC).ConclusionsAnti‐topoisomerase‐I was the commonest autoantibody in patients with systemic sclerosis in Bangladesh. Anti‐RNA polymerase III antibody had significant association with raised PASP and anti‐U1‐RNP with decreased FVC.
Synthesizing the impacts of information and communication technology advancement and educational developments on environmental sustainability: A comparative analyses of three economic blocs—BRICS, MINT, and G7 economies
Authors: Gyamfi Bright Akwasi , Onifade Stephen Taiwo , Ofori Elvis Kwame 
Published: September 2022

AbstractIn the wake of the growing threats to humanity from climate change, we analyzed the information and communications technology (ICT)/education—environmental nexus from three distinct blocs including BRICS, MINT, and the G7 economies between 1990 and 2020. Two models were examined to reach the study's objectives. The first model evaluates whether education and ICT are essential for environmental sustainability via potential reduction in carbon emission. On the other hand, the second model fills an existing gap in extant studies by examining the prospect of education and ICT in influencing citizens on the importance of transition to renewable energy usage. Driscoll and Kraay estimator was employed as a panacea tool for cross‐sectional dependence and slope homogeneity while the fixed effect approach provides sufficient robustness checks on the findings. While some outcomes vary per bloc, others are relatively similar across the three blocs. Education level in school enrollment perspectives shows a negative significant pollution reduction effect across the three blocs, while only the G7 bloc performed better from human capital perspectives. The combined sample bloc shows that ICT also significantly reduces carbon emission, however, an individual bloc analysis refutes this stance for the MINT bloc. Additionally, while renewable energy cushions emissions in all the blocs, rapid urbanization, shows a positive CO2 emission impact except in the G7 bloc. Last, ICT and education significantly boost renewable energy usage only in the G7. Hence, governments and stakeholders in the blocs should gravitate toward greater investments in quality education and greener ICT infrastructures for a sustainable environment.
The nexus of United Nations' 2030 Agenda and corporate sustainability reports
Authors: Tsalis Thomas A. , Terzaki Maria , Koulouriotis Dimitrios , Tsagarakis Konstantinos P. , Nikolaou Ioannis E. 
Published: September 2022

AbstractThe role of corporate responsibility in the protection of the natural environment is unquestionably a key factor in achieving a stable and sustainable future for modern economies and societies. Thus, the business community implements practices to protect the natural environment and eliminate its negative impacts. Such corporate practices are placed under the umbrella of the sustainable development concept which pursues multifaceted economical environmental and social goals and more recently the 17 sustainable development goals (SDGs) of the United Nations' (UN) 2030 Agenda. In this context, this paper aims at examining corporate reporting behavior in the energy sector in relation to SDG disclosures during the first years of the introduction of Agenda 2030. An assessment framework was designed to assess the quality and the range of information disclosed in a set of 105 sustainability reports published during the period 2016–2018. The findings of the empirical analysis led to the conclusion that the examined energy firms did not provide an adequate level of information regarding corporate actions toward the 2030 Agenda for sustainable development. Both the quality of disclosed information and the number of disclosure topics were low. SDG4 was the main focus of the reports, with the highest reporting performance, whereas the issues covered by SDG16 and SDG1 were discussed the least in the examined reports. Also, in practical terms, the proposed methodology provides a sound basis for further investigation of the sustainability reporting practices from the energy sector in relation to the scope of SDG.
Microwave and Ultrasonic‐Assisted Synthesis of Highly Functionalized Carbazoles And Dibenzofurans from Biaryl‐Triazenes Promoted by Acidic Ionic Liquid
Authors: Kim Kang Min , Sutar Suraj M. , Kalkhambkar Rajesh G. , Refat Moamen S. , Alsuhaibani Amnah Mohammed 
Published: September 2022

AbstractBrønsted acidic Ionic liquid promoted synthesis of functionalized carbazoles and dibenzofurans is reported employing biaryl‐triazene as intermediate. The shorter reaction time, diverse functional group tolerance, high yield, mild reaction condition and employment of microwave and ultrasonic assistance highlight the importance of this reaction. Approximately 80–92% of the product yield was achieved with this highly efficient green technique. Along with this, recycling and re‐use of ionic liquids are also addressed.
New Design and Construction of Hierarchical Porous Ni/SiO2 Catalyst with Anti‐sintering and Carbon Deposition Ability for Dry Reforming of Methane
Authors: San Xiaoguang , Cui Jia , Chu Yanxing , Xu Juhua , Meng Dan , Pan Zhiyuan , Wang Guosheng , Qi Jian , Jin Quan 
Published: September 2022

AbstractRecently, low‐resistance to sintering and carbon deposition used in dry reforming of methane (DRM) limits their industrial application. In this study, we synthesized the better anti‐carbon deposition performance of a novel Ni/SiO2 catalyst which has hierarchical porous flower‐like structure by hydrothermal method. A series of characterizations were carried out by different test methods, and the results confirmed that the material had typical hierarchical porous structure, high specific surface areas, and strong metal‐support interaction. The catalyst activity tests at 700 °C in 40 h reaction manifested that CO2 and CH4 conversions of the flower‐like structure of Ni/SiO2 (F‐Ni/SiO2) (87.44% and 79.56%) are higher than that of Ni/SiO2 by the conventional impregnation method (C‐Ni/SiO2) (71.79% and 62.30%). The main reasons can be explained that the large specific surface area, Ni particles were well dispersed on the support surface, and the interaction between the active metal and support of the flower‐like structure of F‐Ni/SiO2 catalyst, have better stability and catalytic performance. Meanwhile, the TG result also showed that the F‐Ni/SiO2 catalyst had better anti‐carbon deposition performance than the traditional catalyst, which leading to a higher catalytic activity.
Nanoscale Synergetic Effects on Ag–TiO2 Hybrid Substrate for Photoinduced Enhanced Raman Spectroscopy (PIERS) with Ultra‐Sensitivity and Reusability
Authors: Shondo Josiah , Veziroglu Salih , Tjardts Tim , Sarwar Tamim Bin , Mishra Yogendra Kumar , Faupel Franz , Aktas Oral Cenk 
Published: September 2022

AbstractHere, a 4N‐in‐1 hybrid substrate concept (nanocolumnar structures, nanocrack network, nanoscale mixed oxide phases, and nanometallic structures) for ultra‐sensitive and reliable photo‐induced‐enhanced Raman spectroscopy (PIERS), is proposed. The use of the 4N‐in‐1 hybrid substrate leads to an ≈50‐fold enhancement over the normal surface‐enhanced Raman spectroscopy, which is recorded as the highest PIERS enhancement to date. In addition to an improved Raman signal, the 4N‐in‐1 hybrid substrate provides a high detection sensitivity which may be attributed to the activation possibility at extremely low UV irradiation dosage and prolonged relaxation time (long measurement time). Moreover, the 4N‐in‐1 hybrid substrate exhibits a superior photocatalytic degradation performance of analytes, allowing its reuse at least 18 times without any loss of PIERS activity. The use of the 4N‐in‐1 concept can be adapted to biomedicine, forensic, and security fields easily.
Recent Advances in Self‐Supported Semiconductor Heterojunction Nanoarrays as Efficient Photoanodes for Photoelectrochemical Water Splitting
Authors: Liu Jinlong , Luo Ziyu , Mao Xichen , Dong Yusong , Peng Lishan , Sun‐Waterhouse Dongxiao , Kennedy John V. , Waterhouse Geoffrey I. N. 
Published: September 2022

AbstractGrowth of semiconductor heterojunction nanoarrays directly on conductive substrates represents a promising strategy toward high‐performance photoelectrodes for photoelectrochemical (PEC) water splitting. By controlling the growth conditions, heterojunction nanoarrays with different morphologies and semiconductor components can be fabricated, resulting in greatly enhanced light‐absorption properties, stabilities, and PEC activities. Herein, recent progress in the development of self‐supported heterostructured semiconductor nanoarrays as efficient photoanode catalysts for water oxidation is reviewed. Synthetic methods for the fabrication of heterojunction nanoarrays with specific compositions and structures are first discussed, including templating methods, wet chemical syntheses, electrochemical approaches and chemical vapor deposition (CVD) methods. Then, various heterojunction nanoarrays that have been reported in recent years based on particular core semiconductor scaffolds (e.g., TiO2, ZnO, WO3, Fe2O3, etc.) are summarized, placing strong emphasis on the synergies generated at the interface between the semiconductor components that can favorably boost PEC water oxidation. Whilst strong progress has been made in recent years to enhance the visible‐light responsiveness, photon‐to‐O2 conversion efficiency and stability of photoanodes based on heterojunction nanoarrays, further advancements in all these areas are needed for PEC water splitting to gain any traction alongside photovoltaic‐electrochemical (PV‐EC) systems as a viable and cost‐effective route toward the hydrogen economy.
The Effects of Dually Modified (Hydrolyzed‐Hydroxypropylated) Sago Starch on the Quality Characteristics of Frozen Dough and Bread
Authors: Ghalambor Pantea , Asadi Gholamhassan , Mohammadi Nafchi Abdorreza , Seyedin Ardebili Seyed Mahdi 
Published: September 2022

AbstractThe purpose of this research is to investigate the possibility of using chemically modified sago starch in frozen dough and bread. The sago starch is first modified by acid hydrolysis (AHS) and hydroxypropylation (HPS) alone or in combination (AHHPS) and then incorporated into burger bread formulation at 10%(W/W) and tested at room temperature for five days. The results indicated that the addition of AHS to the dough reduced the dough stability time and increased the dough development time. The dough containing AHHPS hava a shorter stability time and a longer expansion time than the control. The addition of the single and dual modified sago starches significantly reduced the extensibility and increased extensograph ratio. With the addition of sago starches, there is no significant change in the percentage of freezable water in the dough and the enthalpy of ice melting, but the specific volume of bread is reduced. The use of HPS, followed by AHHPS in bread formulation, is able to better retain moisture in bread during the storage period and significantly reduce the staling intensity in bread. Finally, the results demonstrated that HPS could be used to maintain the quality of bread and delay retrogradation and staling during storage.
Survey of porcine circovirus type 2 and parvovirus in swine breeding herds of Colombia
Authors: Uribe‐García Heinner F. , Suarez‐Mesa Rafael A. , Rondón‐Barragán Iang S. 
Published: September 2022

AbstractBackgroundOne of the consequences of the presentation of reproductive failures in sows is the economic losses in production because it alters the estimated values of the volume of production, decreasing the productivity of the farm. Porcine circovirosis by porcine circovirus 2 (PCV2) has been associated with reproductive disorders, and porcine parvovirus (PVP) is one of the pathological agents most related to the presentation of reproductive failure in pigs. In Colombia, there are reports of the presence of PCV2 through molecular techniques, and PVP through serum tests; however, in the department of Tolima, the prevalence of these two viruses is unknown.ObjectiveIn this study, the aim was to establish a report of the prevalence of viruses in five municipalities of the department of Tolima‐Colombia.MethodsBlood samples from 150 breeding sows of five municipalities in Tolima, Colombia, were obtained. Quantitative polymerase chain reaction (qPCR) was used to detect the PCV2 and PVP virus in the blood samples followed by PCR and sequencing of 16 PCR products of the amplification of thecapgene of PCV2. A phylogenetic tree was constructed to identify the genotype of the PCV2 virus.ResultsThe presence of PCV2d in sows was detected in 135 samples (90%), as well as the identification of PVP in 2.6% of the samples. In addition, the phylogenetic analysis showed that 16 isolates were the PCV2d2 genotype.ConclusionPCV2d and PVP were found to coinfect the females, and the identification of variability in regions in the predicted amino acid sequence of the PCV2 capsid may be associated with virus pathogenicity.