bluuebunny/crossref_metadata_2025_split huggingface dataset:
Educational considerations for health professionals to effectively work with clients with complex regional pain syndrome
Authors: Johnston-Devin Colleen , Oprescu Florin , Wallis Marianne , Gray Marion 
Published: June 2022

Introduction
People living with complex regional pain syndrome (CRPS), a rare chronic pain disorder, must become experts in their own self-management. Listening to the voice of the patient is often advocated in the pain literature. However, the patient’s option is rarely asked for or considered by clinicians, even when they live with a condition that health professionals have rarely heard of.

Purpose
To explore what people living with complex regional pain syndrome (CRPS) think health professionals should know about their condition to provide appropriate care.

Design
A heuristic, hermeneutic phenomenological study was conducted asking people about their experiences living with CRPS. This paper reports on the findings of an additional question asked of all participants.

Participants
Seventeen people living with complex regional pain syndrome were interviewed.

Findings
Overwhelmingly, participants felt that health professionals do not know enough about CRPS, or chronic pain and believe their health outcomes are affected by this lack of knowledge. Sub-themes identified were don’t touch unless I say it is okay; be patient with the patient/ it is important to develop a relationship; educate yourself and educate the patient; choose your words carefully and refer to others as needed. An additional theme, it is very hard to describe CRPS was also identified.

Conclusions
Including patients as a member of the healthcare team is recommended to help people take control and self-manage their pain. For true patient centered care to be achieved, health professionals must accept and respect patients’ descriptions of pain and their pain experience. This may require additional health professional education at both undergraduate and post-graduate levels in pain and communication to increase their bedside manner and therapeutic communication to deliver care in partnership with the patient.
Risk factors associated with self-medication among the indigenous communities of Chittagong Hill Tracts, Bangladesh
Authors: Saha Ayan , Marma Kay Kay Shain , Rashid Afrah , Tarannum Nowshin , Das Srabanty , Chowdhury Tonmoy , Afrin Nusrat , Chakraborty Prashanta , Emran Md. , Mehedi H. M. Hamidullah , Hussain Mohammad Imdad , Barua Ashim , Mistry Sabuj Kanti 
Published: June 2022

Background
In developing countries like Bangladesh, self-medication has become a predicament associated with health risks and clinical complications. To date, no studies have been conducted on the practice of self-medication among the indigenous population living in Chittagong Hill Tract (CHT).

Objectives
This study was aimed to determine the prevalence of self-medication and analyzing the factors associated with it among the indigenous population in CHT.

Methods
This cross-sectional study was conducted from late October to early December 2020; among different indigenous group populations residing in the three districts of CHT aged 18 or more. A pre-tested and semi-structured questionnaire was developed to collect data on socio-demographic characteristics, health status, frequency of self-medication, reasons for self-medication in last one year, as well as other variables. Multivariate logistic regression was performed to assess associated factors with self-medication.

Results
A total of 1350 people from different indigenous populations were interviewed, among whom 49.9% practiced self-medication. The rate of self-prescribed antibiotics usage (80.9%) was significantly higher compared to other drugs. Self-prescribed medications were mostly used for diarrhea and food poisoning (60.6%), cough, cold and fever (51.4%), and headache (51.4%). A common source of self-prescribed medicines was community or retail pharmacy and the most reported reason for self-prescribed medication was the long-distance of healthcare facilities from home.

Conclusion
The prevalence of self-medication is substantially high among indigenous people and the effect is alarming. Particular concern is the misuse of antibiotics and analgesic drugs. Increasing awareness among the population of the negative effect of self-medication and implementation of proper policies and actions are urgently needed to prevent self-medication among indigenous population in Bangladesh.
Telephone Reminders Improve Fecal Immunochemical Test Return Rates
Authors: Jasurda Jake S. , Danieli Reut , Yamanaka Bradley , Shaukat Aasma 
Published: June 2022

INTRODUCTION:
The aim of this study was to investigate the effect of a structured telephone reminder system on completion rates of screening fecal immunochemical tests.

METHODS:
Fecal immunochemical test (FIT) return rates were compared among patients who received a telephone reminder after 14 days and those who did not receive a reminder.

RESULTS:
There was a significantly higher return rate among patients who received a telephone reminder. Automated FIT tracking processes failed to capture a significant percentage of returned FITs compared with manual tracking processes.

DISCUSSION:
These results support telephone reminders as an effective modality to increase FIT return rates.
Optimal Wireless Reflux Monitoring Metrics to Predict Discontinuation of Proton Pump Inhibitor Therapy
Authors: Yadlapati Rena , Gyawali C. Prakash , Masihi Melina , Carlson Dustin A. , Kahrilas Peter J. , Nix Billy Darren , Jain Anand , Triggs Joseph R. , Vaezi Michael F. , Kia Leila , Kaizer Alexander , Pandolfino John E. 
Published: June 2022

INTRODUCTION:
Ambulatory reflux monitoring performed off proton pump inhibitor (PPI) is the gold standard diagnostic test for nonerosive gastroesophageal reflux disease (GERD). However, the diagnostic metrics and optimal duration of monitoring are not well defined. This study evaluated the performance of multiple metrics across distinct durations of wireless reflux monitoring off PPI against the ability to discontinue PPI therapy in patients with suboptimal PPI response.

METHODS:
This single-arm clinical trial performed over 4 years at 2 centers enrolled adults with troublesome GERD symptoms and inadequate response to >8 weeks of PPI. Participants underwent 96-hour wireless pH monitoring off PPI. Primary outcome was whether the subject successfully discontinued PPI or resumed PPI within 3 weeks.

RESULTS:
Of 132 participants, 30% discontinued PPI. Among multiple metrics assessed, total acid exposure time (AET) of 4.0% performed best in predicting PPI discontinuation (odds ratio 2.9 [95% confidence interval 1.4, 6.4]; P = 0.006), with other thresholds of AET and DeMeester score performing comparably. AET was significantly higher on day 1 of monitoring compared with other days, and prognostic performance significantly declined when only assessing the first 48 hours of monitoring (area under the curve for 96 hours 0.63 vs area under the curve for 48 hours 0.57; P = 0.01).

DISCUSSION:
This clinical trial highlights the AET threshold of 4.0% as a high-performing prognostic marker of PPI discontinuation. 96 hours of monitoring performed better than 48 hours, in predicting ability to discontinue PPI. These data can inform current diagnostic approaches for patients with GERD symptoms who are unresponsive to PPI therapy.
Komposisi Vegetasi Habitat Lutung Jawa (Trachypithecus auratus) di Kawasan Wana Wisata Kalipaingan Kabupaten Pekalongan
Authors: Kurniawan Arif , Baskoro Karyadi , Jumari J 
Published: June 2022

Declining population of javan langur caused by several factors such as deforestation and forest fragmentation which are the main habitat for langurs. the vegetation composition of the langur habitat is very important with regard to the density and dominance of trees that have special functions such as tree feed sources, trees at rest and sleeping trees. Research on Javan langur habitat had been conducted Wana Wisata Kalipaingan, Pekalongan Regency. Habitat data, as vegetation community and abiotic factor also collected. The research was conducted in March-July 2018. Tree spesies that has the largest INP value is petung bamboo (Dendrocalamus asper) followed by bendo (Atrocorpus elasticus). There are 9 spesies used as feed sources. 3 spesies are used as resting places and 1 tree spesies asa a sleep places.
Produksi dan Profil Metabolit Bunga Krisan (Chrysanthemum sp.) pada Intensitas Cahaya Lampu LED dengan Durasi Yang Berbeda
Authors: Utami Ika Nur , Nurchayati Yulita , Hastuti Endah Dwi 
Published: June 2022

Chrysanthemum is a Short Day Plant (SDP) that will flower if the day length is less than 12 hours. Indonesian Chrysanthemum farmers provide additional light at night to maintain the Chrysanthemum’s vegetative phase so obtained the stem length which accordance to the cut flower standard (±76 cm). In other side, Chrysanthemum flowers are known has contain metabolites product and potentially useful. This study is purpose to determine the effect of differences in LED light intensity and light exposure duration on growth, flower production, and metabolites profile of chrysanthemum. The study used a RAL method 3x2 factorial pattern which is in the form of giving an additional light intensity of 0 W, 10 W and 20 W and an additional light exposure duration of 2 hrs and 4 hrs. The results showed that the combination of 20 W + 4 hrs is optimaly increases the stem length (96,2 cm) and flowers diameter (6,6 cm). The 20 W light intensity is optimally inhibits the flower initiation and increases the amount of flower. The most compounds produced by chrysanthemum are from fatty acid groups, then hydrocarbons, and diterpenes. The combination of 10 W + 4 hrs is an optimally increases flower metabolites production that produces the most compounds compared to other treatments.
Identifikasi Jenis Gastropoda Pada Zona Intertidal Pantai Deri Dan Pantai Watotena Kecamatan Ile Boleng Kabupaten Flores Timur
Authors: Hawan Florensia Keneka , Bullu Novi Ivonne , Ballo Apriliana 
Published: June 2022

Gastropods are the class with the largest number of species, because it is a class of mollusk phylum that is most successfulin adapting to various types of marine and freshwater habitats to the terrestrial environment. The research was carried out on the identification of the types of gastropods in the Deri Beach and Watotena Beach with the aim to determine the type of gastropods in the region. The result of researchon the identification of the types of gastropods in the intertidal zone of Deri Beach and Watotena Beach found 9 types of gastropods, including Cypraea caputserpentis 14 individuals, Cypraea moneta 50 individuals, Nerita albicilla 86 individuals, Nerita polita 52 individuals, Nerita costata 39 individuals, Conus flavidus 24 individuals, Cantharus undosus 10 individuals, Morula granulate 213 individuals dan Drupa morum 25 individuals. The result of the calculation of the density obtained the highest density on these two beaches there is the type of Morula granulate which is equal to 2,36 ind/m2 in Deri Beach with a relative density of 60,6%. Based on the calculation of values on both beaches this is categorized as having low diversity because the H’ < 1. Furthermore, in the calculation of the dominance index, values are found on both beaches close to 0 so it is categorized low. In addition, measurements were also taken environmental parameters which include temperature, salinity, pH, and turbidity which result shows that Deri Beach and Watotena Beach have decent conditions for gastropod life.
Bioakumulasi Timbal (Pb) Pada Makroalga Padina australis Hauck Di Perairan Laut Kota Makassar, Sulawesi Selatan
Authors: Supardi Wahyu , Nugroho Andika Puspito 
Published: June 2022

Pb lead metal is one of marine pollution material that can accumulate on macroalga Padina australis. The purpose of this research is to know the accumulation of Pb on P.australis, the abundance, and to know the Pb content correlation with abundance on P. australis. Research conducted on February 2018 in Makassar marine waters. The results indicate that there is a difference of the metal content of Pb on P.australis in each station. The metal content of Pb on the station I was at the range 0,0964-0,1388 ppm, Station II 0,0496-0,1050 ppm, and Station III 0,0597-0,1035 ppm which has exceeded the waters standard limit set>0.008 ppm. The high average Pb concentration on the station I because the station I was closer to the mainland of potentially greater influx of Pb heavy metals on macroalgae. P. australis abundance on a station I 92 individuals, II 152 individuals, and III 319 individuals. The data analysis result shows the value of significant correlations 0.384>0.05 that there is no correlation between the Pb concentrations with abundance but the direction of correlation indicates negative (-0331) which means that if the Pb concentration rises then P. australis abundance will decrease.
Potensi Antifungi Bakteri Asam Laktat dari Saluran Pencernaan Ayam Kampung terhadap Kapang Aspergillus flavus
Authors: Natasia Novera , Jannah Siti Nur , Rukmi MG Isworo 
Published: June 2022

Contamination of Aspergillus flavus can attacks food and feed ingredients, especially seeds during the storage. The using of biological agents, like microbes that have antifungal activity becomes a promising and important solution to be studied. This research aims to find out the antifungal activity of lactic acid bacteria (LAB) from digestive tract of “Kampung” chickens against the growing of A. flavus. Source of the isolates are from colon, ventriculus, and crop. The inoculums of LAB which using were suspension of cell and cell free supernatant (CFS). There were 6 isolates of LAB (Bub1, Bub3, Bub4, V52, C51, and NNB) tested to obtain the potential of antifungal activity, by with well diffusion and and submerged culture method. The results showed that the 5 isolates suspension cell of LAB showed inhibitory zones, except Bub1, whereas all CFS LAB showed the inhibitory zones against the growth of A. flavus in MRSA medium. Furthermore, antifungal activity of LAB against A. flavus to be observed by measuring the dry weight of the mycelium production, as well as the percentage of inhibition during the incubation period. All isolates of LAB, from suspension cell and CFS showing antifungal activity against growth of A. flavus. The Bub3 and NNB isolates, from suspension cell and CFS showed that the best antifungal activity compared to the others.
Contracts and Equality: The Dangers of Non-disclosure Agreements in English Law
Authors: MacMillan Catharine 
Published: June 2022

Abstract
This paper is concerned with the interaction between the principle of equal treatment and non-disclosure agreements in English law. The common use of non-disclosure agreements (also referred to as ‘confidentiality clauses’ or ‘gagging clauses’) as a term in contracts settling possible claims in which harassment or discrimination were alleged came to public prominence in England following the #MeToo movement. There has, though, been little consideration of the enforceability of these non-disclosure agreements as a matter of contract law and the impact of non-disclosure agreements upon equality. This paper examines the legal enforceability of these agreements as a matter of English contract law. It is argued that non-disclosure agreements, designed to obtain silence, work to impede the equality of women. English contract law provides few protections from the potential abuse that can arise from non-disclosure agreements.
Study on stability of grape seed oil/rice hydrolyzed protein emulsion
Authors: Duan Fangyu , Zhang Ying , Wang Yue , Zhang Xu , Zhao Wei , Zhang Hao 
Published: June 2022

Abstract
In this study, the stability mechanism of grape seed oil/rice hydrolyzed protein emulsion was studied. The grape seed oil (10% v/v) and rice hydrolyzed protein (2% w/v) were homogenized under high pressure to prepare the emulsion. It was observed by CLSM and Multiple light scatterometer that the emulsion had long-term storage stability, and the average particle size of droplets was 0.984–1.363 µm. ζ-potential ranged from −37.733 mV to −25.633 mV. It is found that the emulsion has strong resistance to temperature, ions and other environmental factors from the macroscopic and microscopic structure, and no emulsion stratification phenomenon occurs. The composite emulsion can be used in the field of food industry and fine chemical industry, which can provide nutrition and functionality of products, its research has certain value and has a wide space for development.
Implementation of the Spark technique in a matrix distributed computing algorithm
Authors: Wang Ying , Cengiz Korhan 
Published: June 2022

Abstract
Two analyzes of Spark engine performance strategies to implement the Spark technique in a matrix distributed computational algorithm, the multiplication of a sparse multiplication operational test model. The dimensions of the two input sparse matrices have been fixed to 30,000 × 30,000, and the density of the input matrix have been changed. The experimental results show that when the density reaches about 0.3, the original dense matrix multiplication performance can outperform the sparse-sparse matrix multiplication, which is basically consistent with the relationship between the sparse matrix multiplication implementation in the single-machine sparse matrix test and the computational performance of the local native library. When the density of the fixed sparse matrix is 0.01, the distributed density-sparse matrix multiplication outperforms the same sparsity but uses the density matrix storage, and the acceleration ratio increases from 1.88× to 5.71× with the increase in dimension. The overall performance of distributed operations is improved.
Robust, Long-Term Video EEG Monitoring in a Porcine Model of Post-Traumatic Epilepsy
Authors: Martinez-Ramirez Luis , Slate Andrea , Price George D. , Duhaime Ann-Christine , Staley Kevin J. , Costine-Bartell Beth A. 
Published: June 2022

AbstractTo date, post-traumatic epilepsy (PTE) research in large-animal models has been limited. Recent advances in neocortical microscopy have made possible new insights into neocortical PTE. However, it is very difficult to engender convincing neocortical PTE in rodents. Thus, large-animal models that develop neocortical PTE may provide useful insights that also can be more comparable to human patients. Because gyrencephalic species have prolonged latent periods, long-term video EEG recording is required. Here, we report a fully subcutaneous EEG implant with synchronized video in freely ambulatory swine for up to 13 months during epileptogenesis following bilateral cortical impact injuries or sham surgery The advantages of this system include the availability of a commercially available system that is simple to install, a low failure rate after surgery for EEG implantation, radiotelemetry that enables continuous monitoring of freely ambulating animals, excellent synchronization to video to EEG, and a robust signal-to-noise ratio. The disadvantages of this system in this species and age are the accretion of skull bone, which entirely embedded a subset of skull screws and EEG electrodes, and the inability to rearrange the EEG electrode array. These disadvantages may be overcome by splicing a subdural electrode strip to the electrode leads so that skull growth is less likely to interfere with long-term signal capture and by placing two implants for a more extensive montage. This commercially available system in this bilateral cortical impact swine model may be useful to a wide range of investigators studying epileptogenesis in PTE.
Vapor phase growth and properties of mixed layered Pb1-xCdxI2 semiconductors
Authors: Rybak O.V. , Chekaylo M.V. , Pokladok N.T. 
Published: June 2022

Pb1-xCdxI2 crystals (x = 0.1; 0.9) have been obtained by crystallization from a vapour phase in a closed system at over-stoichiometric iodine vapour pressure. An alloy of CdI2 and PbI2 was used as a source of evaporation. As a result of X-ray diffraction studies, it has been found that the obtained crystals belong to 4H-polytype, the space symmetry group is P63mc. The lattice parameters and the unit cell volume of crystals have been determined: for Pb0.9Cd0.1I2 a = 4,529 Å, c = 13,96 Å, V = 247,9 Å3; for Pb0.1Cd0.9I2 a = 4.258 Å, c = 13.70 Å, V = 215.0 Å3. The morphology of Pb1-xCdxI2 solid solutions crystals has been studied by scanning electron microscopy. Grown light orange Pb0.9Cd0.1I2 crystals have the shape of plates and ribbons, the surface of which is sculpted by growth figures. The transparent mixed Pb0.1Cd0.9I2 crystals have been grown from the vapour phase only in the form of plates. The spectral dependences of the optical absorption of Pb1-xCdxI2 crystals at room temperature have been studied. The optical widths of the band gaps of the grown crystals have been determined from the absorption spectra using the Tauc relation.
Theoretical approaches and Monte Carlo simulations in a clinical proton beam
Authors: N Teles Tarcisio , D Morás Laura , A. Pianoschi Thatiane , T. Pazzianotto Maurício , Bonatto Alexandre 
Published: June 2022

Proton therapy is an interesting alternative to conventional radiotherapy, especially for treating localized tumors near important and/or sensitive parts of the human body. Protons, due to their electric charge and mass, interact with the propagating media in such a way that a well localized maximum - known as the Bragg peak - is observed if a depth dose deposition curve is plotted. Since the Bragg peak location depends on the initial proton energy beam, by adjusting this parameter it can be placed over the tumor to be treated. In addition, because the dose deposition goes to zero right after this peak, the health tissue after the tumor is spared if proton therapy is adopted. However, despite the aforementioned advantages, many issues prevent a wider adoption of proton therapy over radiotherapy. In addition to the very high implementation cost, unsolved technical issues, such as, the uncertainty in the proton beam range within the medium, or the correct dose prediction at the Bragg peak, must be addressed. This research aims to investigate the validity of theoretical approximations for the solution of Bethe equation. Such approaches are compared to results from Monte Carlo simulations, executed with the MCNPX code, and reference values ​​from the literature as well for the proton beam range and the energy deposition in the medium. A parameter is proposed and adopted to quantify the global difference between the theoretical approximations evaluated in this work with respect to the Monte Carlo simulation results.
Reviewing therapy with radioisotopes for pain bone metastasis and its possible evolution
Authors: Coiro Silva Daniel , Jose Meyer Nascimento Roberto 
Published: June 2022

Introduction: The therapy with radioisotopes is widely used, its beginnings were focused on thyroid pathologies treatments. Over the years, the radiopharmaceuticals and/or radioisotopes have had their usage increased, to be used on painful bone metastasis. Material and Methods: A bibliographic search was conducted in the major health Science basis to evaluate what the therapies have to offer for patients in this condition. Results: Currently there are only two available materials in Brazil, the Sm153 that is national production, and Ra223, that is imported. Outside Brazil we can find a variety of materials that have already been approved by the Sanitary Organization in other countries, even though we are not authorized to use them due to Brazilian Regulation and production issues. Conclusion: Besides the diversity of materials that could be used, dosimetry systems must be implemented in order to have a more efficient treatment and to have an accurate administrated activities to patients.