bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endoscopic management of non-ampullary duodenal adenomas
Authors: Coriat Romain , Barret Maximilien , Amoyel Maxime , Belle Arthur , Dhooge Marion , Ali Einas Abou , Hallit Rachel , Prat Frederic , Dohan Anthony , Terris Benoit , Chaussade Stanislas 
Published: January 2022

AbstractDuodenal polyps are found in 0.1 % to 0.8 % of all upper endoscopies. Duodenal adenomas account for 10 % to 20 % of these lesions. They can be sporadic or occur in the setting of a hereditary predisposition syndrome, mainly familial adenomatous polyposis. Endoscopy is the cornerstone of management of duodenal adenomas, allowing for diagnosis and treatment, primarily by endoscopic mucosal resection. The endoscopic treatment of duodenal adenomas has a high morbidity, reaching 15 % in a prospective study, consisting of bleeding and perforations, and should therefore be performed in expert centers. The local recurrence rate ranges from 9 % to 37 %, and is maximal for piecemeal resections of lesions > 20 mm. Surgical resection of the duodenum is flawed with major morbidity and considered a rescue procedure in cases of endoscopic treatment failures or severe endoscopic complications such as duodenal perforations. In this paper, we review the existing evidence on endoscopic diagnosis and treatment of non-ampullary duodenal adenomas.
Mucormycosis: An Uncommon Cutaneous Infection at Permanent Pacemaker-Implanted Site in a Very Low-Birthweight Baby
Authors: Choudhury Minati , Narula Jitin , Hote Milind P. , Mohapatra Sarita 
Published: January 2022

AbstractPermanent pacemaker implantation in low birthweight (LBW) babies with congenital complete heart block is extremely challenging due to a paucity of appropriate pulse generator placement pocket sites. The development of infection following an implantation procedure can pose a life-threatening risk to the patients. With more patients in the younger group receiving these devices than ever before and the rate of infection increasing rapidly, a closer look at the burden of infection and its impact on outcome of these patients is warranted. We report mucormycosis infection at the abdominal pacemaker pocket site of an infant requiring pacemaker explantation and re-insertion into the intrapleural space.
Comparative Analysis of Surgical Exposure among Endoscopic Endonasal Approaches to Petrosectomy: An Experimental Study in Cadavers
Authors: Loymak Thanapong , Belykh Evgenii , Abramov Irakliy , Tungsanga Somkanya , Sarris Christina E. , Little Andrew S. , Preul Mark C. 
Published: January 2022

Abstract
Objectives Endoscopic endonasal approaches (EEAs) for petrosectomies are evolving to reduce perioperative brain injuries and complications. Surgical terminology, techniques, landmarks, advantages, and limitations of these approaches remain ill defined. We quantitatively analyzed the anatomical relationships and differences between EEA exposures for medial, inferior, and inferomedial petrosectomies.
Design This study presents anatomical dissection and quantitative analysis.
Setting Cadaveric heads were used for dissection. EEAs were performed using the medial petrosectomy (MP), the inferior petrosectomy (IP), and the inferomedial petrosectomy (IMP) techniques.
Participants Six cadaver heads (12 sides, total) were dissected; each technique was performed on four sides.
Main Outcomes and Measures Outcomes included the area of exposure, visible distances, angles of attack, and bone resection volume.
Results The IMP technique provided a greater area of exposure (p < 0.01) and bone resection volume (p < 0.01) when compared with the MP and IP techniques. The IMP technique had a longer working length of the abducens nerve (cranial nerve [CN] VI) than the MP technique (p < 0.01). The IMP technique demonstrated higher angles of attack to specific neurovascular structures when compared with the MP (midpons [p = 0.04], anterior inferior cerebellar artery [p < 0.01], proximal part of the cisternal CN VI segment [p = 0.02]) and IP (flocculus [p = 0.02] and the proximal [p = 0.02] and distal parts [p = 0.02] of the CN VII/VIII complex) techniques.
Conclusion Each of these approaches offers varying degrees of access to the petroclival region, and the surgical approach should be appropriately tailored to the pathology. Overall, the IMP technique provides greater EEA surgical exposure to vital neurovascular structures than the MP and the IP techniques.
‘Broken English’, ‘dialect’ or ‘Bahamianese’?
Authors: Laube Alexander , Rothmund Janina 
Published: January 2022

AbstractThe study investigates language attitudes in The Bahamas, addressing the current status of the local creole in society as well as attitudinal indicators of endonormative reorientation and stabilization. At the heart of the study is a verbal guise test which investigates covert language attitudes among educated Bahamians, mostly current and former university students; this was supplemented by a selection of acceptance rating scales and other direct question formats. The research instrument was specifically designed to look into the complex relationships between Bahamian Creole and local as well as non-local accents of standard English and to test associated solidarity and status effects in informal settings. The results show that the situation in The Bahamas mirrors what is found for other creole-speaking Caribbean countries in that the local vernacular continues to be ‘the language of solidarity, national identity, emotion and humour, and Standard the language of education, religion, and officialdom’ (Youssef 2004: 44). Notably, the study also finds that standard Bahamian English outranks the other metropolitan standards with regard to status traits, suggesting an increase in endonormativity.
OuroborosBEM: a fast multi-GPU microscopic Monte Carlo simulation for gaseous detectors and charged particle dynamics
Authors: Quéméner G. , Salvador S. 
Published: January 2022

Abstract
The design of gaseous detectors for accelerator, particle and nuclear physics requires simulations relying on multi-physics aspects. In fact, these simulations deal with the dynamics of a large number of charged particles interacting in a gaseous medium immersed in the electric field generated by a more or less complex assembly of electrodes and dielectric materials. We report here on a homemade software, called ouroborosbem, able to tackle the different features involved in such simulations.
After solving the electrostatic problem for which a solver based on the boundary element method (BEM) has been implemented, particles are tracked and will microscopically interact with the gas medium. Dynamical effects have been included such as the electron-ion recombination process, the charging-up of the dielectric materials and other space charge effects that might alter the detector performances. These were made possible thanks to the nVidia CUDA language specifically optimised to run on Graphical Processor Units (GPUs) to minimize the computing times.
Comparisons of the results obtained for parallel plate avalanche counters and GEM detectors to literature data on swarm parameters fully validate the performances of ouroborosbem. Moreover, we were able to precisely reproduce the measured gains of single and double GEM detectors as a function of the applied voltage.
Spectral shift function for a discretized continuum
Authors: Rubtsova O A , Pomerantsev V N 
Published: January 2022

Abstract
A spectral shift function (SSF) is an important object in the scattering theory which is related both to the spectral density and to the scattering matrix. In the paper, it is shown how to employ the SSF formalism to solve scattering problems when the continuum is discretized, e.g. when solving a scattering problem in a finite volume or in the representation of some finite square-integrable basis. A new algorithm is proposed for reconstructing integrated densities of states and the SSF using a union of discretized spectra corresponding to a set of Gaussian bases with the shifted scale parameters. The examples given show that knowledge of the discretized spectra of the total and asymptotic Hamiltonians is sufficient to find the scattering partial phase shifts at any required energy, as well as the resonances parameters.
Calculation features of compressed-bent build-up timber columns with nonlinear-deformable shear bracings
Authors: Popov E V , Karelsky A V , Sopilov V V , Labudin B V , Cherednichenko V V 
Published: January 2022

Abstract
Object of research is build-up compressed–bent and eccentrically compressed columns on yielding nonlinear – deformable shear bracings. Purpose of the research is development of a numerical method for calculation of columns, allowing to take in account the influence of deflection of elastic axis of bar on the increment of the bending moment from the action of longitudinal compressive force and the nonlinear dependence between the forces and deformations in the shear bracings. Problem-solving method consists in dividing the column into separate sections, a system of equations is compiled from the condition of equality of the increment of concentrated shears. The loading process is divided into a set number of stages, at each forces in the shear bracings, the stresses in the branches, and the buckling function of the elastic axis of the element are determined. The obtained values of forces in the shear bracings and buckling are used to specify stiffness of the bracings and component of the bending moment arising due to eccentric application of the longitudinal compressive force when longitudinal axis of the element is deflecting. To obtain the resulting values, the obtained forces, deflections and stresses in the branches at each calculation stage are summed up.
Modeling the system of a dovetailless asynchronous electric drive for conveyor mechanisms
Authors: Pikalov Vladimir Vladimirovich , Boikov Andrei Igorevich , Sdvizkov Andrei Vitalievich , Ponomarev Pavel Sergeevich 
Published: January 2022

Abstract
The article considers a vector control system for asynchronous electric drive of belt conveyors, which uses an adaptive observer to control the speed of the electric drive. This allows you to increase the reliability and inter-interval maintenance of the electric drive. The requirements for the observer are determined, its mathematical description is made, and the law of adaptation is determined. In the Matlab Simulink package, a computer simulation of the proposed sensor-free control system is performed. A study of the robustness of the actuator in terms of the drift of the parameters of the motor when powered from the inverter, expressed by the integral criterion for parametric robustness. Based on the results obtained, a comparison is made and conclusions are drawn about the advantages and disadvantages of using an adaptive observer in comparison with other types of observers.
Fretting tribological performance of DLC, TiAlN and DLC/TiAlN coatings deposited on carburized 18CrNi4A steel
Authors: Xiao Li , Xu Yingqiang , Chen Zhiyong 
Published: January 2022

Abstract
To improve the fretting wear performance of 18CrNi4A steel, DLC, TiAlN and DLC/TiAlN coatings were deposited on the surface of carburized 18CrNi4A steel, respectively. The microstructure morphologies, chemical compositions, and mechanical properties of these coatings were evaluated. The fretting tribological properties of pad/flat contact pairs for carburized 18CrNi4A steel, DLC, TiAlN and DLC/TiAlN coatings were investigated in different lubricant environments including dry sliding and #RIPP 7254 aviation grease. The results show that DLC, TiAlN and DLC/TiAlN coatings deposited on the carburized 18CrNi4A steel surface can improve surface roughness, hardness, fracture toughness and resistance to plastic deformation. DLC, TiAlN and DLC/TiAlN coatings deposited on the surface of carburized 18CrNi4A steel can make the surface of the substrate have excellent fretting wear properties. DLC and DLC/TiAlN coatings have lower coefficient of friction and better fretting wear resistance than TiAlN coatings in dry sliding condition, and DLC/TiAlN coatings have the lowest wear rate in #RIPP 7254 grease lubrication condition. In addition, the wear mechanisms of carburized 18CrNi4A steel, DLC, TiAlN and DLC/TiAlN coatings in dry sliding and #RIPP 7254 aviation grease conditions were analyzed.
Effects of tensile stress on electrochemical characteristics and structural morphology of P110SS steels in carbon dioxide-saturated solution
Authors: Wang Shuliang , Yao Mengjun , Jing Yangzhong , He Xujia , Bao Mingyu , Liu Li , Xiang Dinghan 
Published: January 2022

Abstract
A high-temperature autoclave was used to grow CO2 corrosion-product films on P110SS steel specimens while the surface of the specimens was continuously subjected to tensile stress in a four-point bending jig; the autoclaving times were 6, 18, 36, and 72 h. A scanning electron microscope was used to observe the surface topography of the corrosion-product films formed on the P110SS steels. An x-ray diffraction was used to analyze the phase compositions of the corrosion products. The electrochemical performance of the films was investigated using electrochemical impedance spectroscopy and potentiodynamic polarization curves. The results showed that tensile stress could hinder the formation of corrosion-product films; the integrity and compactness of the films worsened, but the phase compositions of the films did not change. The applied tensile stress resulted in a smaller grain size of the corrosion-product films, and the grain boundaries increased. In addition, owing to the induced tensile stress, the charge transfer resistances decreased, and the corrosion current densities increased for the P110SS steels with corrosion-product films in a 3.5 wt% NaCl solution saturated with CO2.
Printed zinc tin oxide diodes: from combustion synthesis to large-scale manufacturing
Authors: Carlos Emanuel , Branquinho Rita , Jansson Elina , Leppäniemi Jaakko , Menezes José , Pereira Rita , Deuermeier Jonas , Alastalo Ari , Eiroma Kim , Hakola Liisa , Fortunato Elvira , Martins Rodrigo 
Published: January 2022

Abstract
Printed metal oxide devices have been widely desired in flexible electronic applications to allow direct integration on foils and to reduce electronic waste and associated costs. Especially, semiconductor devices made from non-critical raw materials, such as Zn, Sn (and not, for example, In), have gained significant interest. Despite considerable progress in the field, the upscale requirements from lab to fab scale to produce these materials and devices remain a challenge. In this work, we report the importance of solution combustion synthesis (SCS) when compared with sol–gel in the production of zinc tin oxide (ZTO) thin films using a solvent (1-methoxypropanol) that has lower environmental impact than the widely used and toxic 2-methoxyethanol. To assure the compatibility with low-cost flexible substrates in high-throughput printing techniques, a low annealing temperature of 140 °C was achieved for these thin films by combining SCS and infrared annealing in a short processing time. These conditions allowed the transition from spin-coating (lab scale) to flexographic printing (fab scale) at a printing speed of 10 m min−1 in a roll-to-roll pilot line. The ZTO (1:1 Zn:Sn-ratio) diodes show a rectification ratio of 103, a low operation voltage (⩽3 V), promising reproducibility and low variability. The results provide the basis for further optimisation (device size, encapsulation) to meet the requirements of diodes in flexible electronics applications such as passive-matrix addressing, energy harvesting and rectification.
Augmenting recombinant antibody production in HEK293E cells: optimizing transfection and culture parameters
Authors: Heng Zealyn Shi-Lin , Yeo Joshua Yi , Koh Darius Wen-Shuo , Gan Samuel Ken-En , Ling Wei-Li 
Published: January 2022

Abstract

Background
Optimizing recombinant antibody production is important for cost-effective therapeutics and diagnostics. With impact on commercialization, higher productivity beyond laboratory scales is highly sought, where efficient production can also accelerate antibody characterizations and investigations.

Methods
Investigating HEK293E cells for mammalian antibody production, various transfection and culture parameters were systematically analyzed for antibody light chain production before evaluating them for whole antibody production. Transfection parameters investigated include seeding cell density, the concentration of the transfection reagent and DNA, complexation time, temperature, and volume, as well as culture parameters such as medium replacement, serum deprivation, use of cell maintenance antibiotic, incubation temperature, medium volume, post-transfection harvest day, and common nutrient supplements.

Results
Using 2 mL adherent HEK293E cell culture transfections with 25 kDa linear polyethylenimine in the most optimized parameters, we demonstrated a ~2-fold production increase for light chain alone and for whole antibody production reaching 536 and 49 μg, respectively, in a cost-effective manner. With the addition of peptone, κ light chain increased by ~4-fold to 1032 μg, whereas whole antibody increased to a lesser extent by ~2.5-fold to 51 μg, with benefits potentially for antibodies limited by their light chains in production.

Conclusions
Our optimized findings show promise for a more efficient and convenient antibody production method through transfection and culture optimizations that can be incorporated to scale-up processes and with potential transferability to other mammalian-based recombinant protein production using HEK293E.
Contextual factors influencing complex intervention research processes in care homes: a systematic review and framework synthesis
Authors: Peryer Guy , Kelly Sarah , Blake Jessica , Burton Jennifer K , Irvine Lisa , Cowan Andy , Akdur Gizdem , Killett Anne , Brand Sarah L , Musa Massirfufulay Kpehe , Meyer Julienne , Gordon Adam L , Goodman Claire 
Published: January 2022

Abstract

Background
Care homes are complex settings to undertake intervention research. Barriers to research implementation processes can threaten studies’ validity, reducing the value to residents, staff, researchers and funders. We aimed to (i) identify and categorise contextual factors that may mediate outcomes of complex intervention studies in care homes and (ii) provide recommendations to minimise the risk of expensive research implementation failures.

Methods
We conducted a systematic review using a framework synthesis approach viewed through a complex adaptive systems lens. We searched: MEDLINE, Embase, CINAHL, ASSIA databases and grey literature. We sought process evaluations of care home complex interventions published in English. Narrative data were indexed under 28 context domains. We performed an inductive thematic analysis across the context domains.

Results
We included 33 process evaluations conducted in high-income countries, published between 2005 and 2019. Framework synthesis identified barriers to implementation that were more common at the task and organisational level. Inductive thematic analysis identified (i) avoiding procedural drift and (ii) participatory action and learning as key priorities for research teams. Research team recommendations include advice for protocol design and care home engagement. Care home team recommendations focus on internal resources and team dynamics. Collaborative recommendations apply to care homes’ individual context and the importance of maintaining positive working relationships.

Discussion
Researchers planning and undertaking research with care homes need a sensitive appreciation of the complex care home context. Study implementation is most effective where an intervention is co-produced, with agreed purpose and adequate resources to incorporate within existing routines and care practices.
Referral to geriatric rehabilitation: a scoping review of triage factors in acutely hospitalised older patients
Authors: de Groot Aafke J , Wattel Elizabeth M , van Dam Carmen S , van Balen Romke , van der Wouden Johannes C , Hertogh Cees M P M 
Published: January 2022

Abstract

Objective
Old or frail acutely hospitalised patients can benefit from geriatric rehabilitation but criteria concerning referral decisions are unclear. This review presents an overview of clinical factors associated with referral to geriatric rehabilitation that may further consensus between hospital and rehabilitation professionals on triage.

Design
Scoping review.

Methods
A review was conducted following Arksey and O’Malley’s framework. The search included literature concerning a broad spectrum of acutely hospitalised patients and factors associated with their referral to geriatric rehabilitation.

Results
Selected abstracts were categorised into distinct geriatric rehabilitation care pathways such as stroke, hip fracture, amputation of lower limb, cardiac and oncologic rehabilitation. Abstracts on internal medical patients were further reviewed and 29 studies were included. A total of 13 studies focused on factors identifying rehabilitation needs and 16 on factors associated with outcome of geriatric rehabilitation. Triage factors were diverse and included frailty status, functional decline, cognitive symptoms and multimorbidity. Mood symptoms and living situation further specified post-acute care needs. In overview, triage factors could be characterised as demographic (n = 4), diagnosis-related (n = 8), mental (n = 6), functional (n = 10) or multi-domain (n = 12) and mapped in a transitional care pathway.

Conclusions and implications
Frailty and functional decline are characteristics frequently associated with referral to geriatric rehabilitation of acutely hospitalised internal medical patients. A comprehensive geriatric assessment or a simpler multi-domain set of tests reveals rehabilitation needs and approximates a functional prognosis. Professional consensus on factors and timing of triage in hospital is within reach.
Candidate reactions to a postgraduate year 1 pharmacy residency supplemental application
Authors: Reed Brent N , Armahizer Michael J , Devabhakthuni Sandeep , Lemens Laura , Yeung Siu Yan A 
Published: January 2022

Abstract

Purpose
The purpose of this study was to gauge postgraduate year 1 (PGY1) pharmacy residency candidates’ reactions to supplemental applications, as well as aspects specific to our process, including a personality test and situational judgment test (SJT).

Methods
After rank lists were submitted, applicants to our program were invited to complete an online survey. Outcomes of interest included candidates’ perceptions of relevance and fairness. Whether candidates’ attitudes differed based on the receipt of an interview offer was also assessed.

Results
Of 199 applicants to our program for the 2021-2022 training year, 48 applicants (24.1%) completed the survey, 15 of whom had received an interview offer. Most (64.6%) agreed that supplemental applications were useful, and nearly all (95.8%) indicated that they were willing to submit one for programs in which they were most interested. The process was seen as being fair, although ratings were higher among those who received interview offers. Most respondents believed that the personality test and SJT were relevant to the role of a resident, but attitudes towards the SJT were generally more favorable and less likely to vary according to whether candidates received an interview offer. Candidates believed that the personality test and SJT were not as representative of them as letters of reference or their curriculum vitae, but perceptions of academic performance varied.

Conclusion
Applicants responded positively to our supplemental application and indicated that they would be willing to complete one for programs of interest. These findings should help assuage concerns about the use of supplemental applications, particularly when short-answer or essay formats are avoided.