bluuebunny/crossref_metadata_2025_split huggingface dataset:
The fibro‐ and cyto‐architecture demarcating the border between the dentate gyrus and CA3 in sheep (Ovis aries) and domestic pig (Sus scrofa domesticus)
Authors: Blackstad Jan Sigurd , Osen Kirsten K. , Leergaard Trygve B. 
Published: August 2022

AbstractThe hippocampal formation is essential for spatial navigation and episodic memory. The anatomical structure is largely similar across mammalian species, apart from the deep polymorphic layer of the dentate gyrus and the adjacent part of cornu ammonis 3 (CA3) which feature substantial variations. In rodents, the polymorphic layer has a triangular cross‐section abutting on the end of the CA3 pyramidal layer, while in primates it is long and band‐shaped capping the expanded CA3 end, which here lacks a distinct pyramidal layer. This structural variation has resulted in a confusing nomenclature and unclear anatomical criteria for the definition of the dentate‐ammonic border. Seeking to clarify the border, we present here a light microscopic investigation based on Golgi‐impregnated and Timm–thionin‐stained sections of the Artiodactyla sheep and domestic pig, in which the dentate gyrus and CA3 end have some topographical features in common with primates. In short, the band‐shaped polymorphic layer coincides with the Timm‐positive mossy fiber collateral plexus and the Timm‐negative subgranular zone. While the soma and excrescence‐covered proximal dendrites of the mossy cells are localized within the plexus, the peripheral mossy cell dendrites extend outside the plexus, both into the granular and molecular layers, and the CA3. The main mossy fibers leave the collateral plexus in a scattered formation to converge gradually through the CA3 end in between the dispersed pyramidal cells, which are of three subtypes, as in monkey, with the classical apical subtype dominating near the hidden blade, the nonapical subtype near the exposed blade, and the dentate subtype being the only pyramidal cells that extend dendrites into the dentate gyrus. In agreement with our previous study in mink, the findings show that the border between the dentate gyrus and the CA3 end can be more accurately localized by the mossy fiber system than by cyto‐architecture alone.
Numerical analysis of viscoelastic Maxwell fluid flow through a radiative axisymmetric semi‐porous channel
Authors: Khalid Samra , Zia Qazi M. Z. , Shehzad Sabir A. , Nadeem Aamir 
Published: August 2022

AbstractThe non‐Newtonian fluids have abundant implications in versatile fields of chemical, mechanical, and biological engineering. Furthermore, the non‐Newtonian fluids flowing through the porous medium are very useful in petroleum and industrial engineering. Heat transport analysis with radiation has major appliances in fusion reactors, heat exchangers, solar energy, aircrafts engines, turbine cooling, and many others. Having all these important appliances in view, the present study is focused on the heat transfer analysis of an incompressible two‐dimensional viscoelastic magnetohydrodynamic Maxwell non‐Newtonian liquid flow in a porous space. The magnetic field is uniformly applied tangential to the flow direction and the lower‐channel wall is heated by induction as a consequence of the Lorentz force. The effect of thermal radiation is taken to foresee the physical occurrence of heat kinetics from an applied point of view. Similarity transformation is considered in reducing the governing partial differential equations into ordinary differential equations and a numerical solution is computed using the shooting technique. The results obtained are compared with the published literature. The effects of flow quantities are illustrated graphically and analyzed with physical meaning. In view of engineering applications, the effects of Reynolds on skin friction coefficient and rate of heat transfer are presented.
Scrutiny of convective MHD second‐grade fluid flow within two alternatively conducting vertical surfaces with Hall current and induced magnetic field
Authors: Singh Jitendra K. , Hanumantha  , Seth Gauri S. 
Published: August 2022

AbstractThe focus of this paper is to examine the heat and mass transport behavior of transient magnetohydrodynamics second‐grade fluid (elastico‐viscous fluid) flow within a vertical channel bounding the porous regime with the Hall phenomenon and induced magnetic field (IMF). The flow system consists of a strong transverse magnetic field that gives rise to the Hall phenomenon and IMF. The right vertical surface of the channel is conducting and oscillations in its plane in the vertical direction while the left vertical surface of the channel is nonconducting and stationary. The suitable dimensionless setup transforms the flow model into a simplified comparable model which is solved analytically with the assistance of the method of separation of variables. Numerical computation is performed with the aid of MATHEMATICA software to explore the results from the analytical solutions. The results of the investigation are helpful in analyzing the nature of the elastic‐viscous fluids. A noteworthy result noted from the investigation is that there appears a reverse flow in the direction of normal flow when the magnetic interaction parameter is large. For the small magnetic interaction parameter, such a flow is not seen. Hall current reduces the strength of the principal IMF and induces the strength of the secondary generated magnetic field. Furthermore, it is explored that the elastico‐viscous nature of the second‐grade fluid has a tendency of enhancing the principal flow and principal‐produced magnetic field.
Significance of Casson dissipative fluid and spanwise cosinusoidally fluctuating temperature on unsteady MHD free convective flow past a hot vertical permeable plate with radiation absorption and chemical reaction
Authors: Rajakumar K. V. B. , Murthy P. P. , Govinda Rao T. , Ranganath N. 
Published: August 2022

AbstractThe current analysis concentrated on the consequence of Casson dissipative fluid and spanwise consinusoidally fluctuation temperature on unsteady magnetohydrodynamics free convective flow past a moving hot vertical permeable plate with heat generation, radiation absorption, and chemical reaction. It has imperative practical applications in plentiful fields like physiological processes, biomedical science, food processing, pharmaceutical, chemical material processing engineering, manufacturing systems, and so on. The governing partial differential equations are evaluated analytically by employing a multiple regular perturbation method. The influence of assortment physical estimators on fluid velocity, temperature, concentration, skin friction, Nusselt number, and Sherwood number was illustrated quantitatively through graphs. Eventually, it was revealed that velocity, concentration, and Sherwood number declined with the progressive values of the chemical reaction parameter. Velocity and temperature were enhanced with incremental values of Prandtl number, while the contradictory impact occurred in Nusselt number and skin friction. Meanwhile, velocity and skin friction lessened with the incremental values of the magnetic parameter and Casson fluid parameter.
Drug delivery system based on nanobubbles
Authors: Jin Juan , Yang Li , Chen Feng , Gu Ning 
Published: August 2022

AbstractUltrasound (US) medical technology is widely used due to its advantages of safety, speed, and low cost. With the rapid development of biomedical nanotechnology, micro/nanobubbles, as US contrast agents, are not only valuable in US imaging diagnosis but also show broad application prospects in drug delivery. Nanobubbles (NBs) have more advantages as drug delivery systems (DDSs) due to their smaller size and longer circulation time compared with microbubbles. In this review, the fundamentals of NBs, including classification, stability mechanism, and preparation methods are summarized. Then, the strategies of a DDS based on NBs, including direct delivery, codelivery, target delivery, and stimuli‐responsive delivery are reviewed and discussed. The three main applications of NBs‐based DDSs, namely tumor theranostics, brain drug delivery, and vascular disease theranostics were highlighted. The challenges and future directions of the NBs‐based DDSs are also considered and discussed.
Immunotherapy with anti‐GD2 monoclonal antibody in infants with high‐risk neuroblastoma
Authors: Kushner Brian H. , Modak Shakeel , Kramer Kim , Basu Ellen M. , Iglesias‐Cardenas Fiorella , Roberts Stephen S. , Cheung Nai‐Kong V. 
Published: August 2022

AbstractAnti‐GD2 monoclonal antibodies (mAb) improve the prognosis of high‐risk neuroblastoma (HR‐NB). Worldwide experience almost exclusively involves toddlers and older patients treated after multimodality or second‐line therapies, that is, many months postdiagnosis. In contrast, at our center, infants received anti‐GD2 mAbs because this immunotherapy started during or immediately after induction chemotherapy. We now report on the feasibility, safety, and long‐term survival in this vulnerable age group. Thirty‐three HR‐NB patients were <19 months old when started on 3F8 (murine mAb; n = 21) or naxitamab (humanized‐3F8; n = 12), with 30″ to 90″ intravenous infusions. Patients received analgesics and antihistamines. Common toxicities (pain, urticaria, cough) were manageable, allowing outpatient treatment. Capillary leak, posterior reversible encephalopathy syndrome, and mAb‐related long‐term toxicities did not occur. Two 3F8 cycles were aborted due to bradycardia (a preexisting condition) and asthmatic symptoms, respectively. One patient received ½ dose of Day 1 naxitamab because of hypotension; full doses were subsequently administered. Post‐mAb treatments included chemotherapy, radiotherapy, and anti‐NB vaccine. Among 3F8 patients, 17/21 are in complete remission off all treatment at 5.6+ to 24.1+ (median 13.4+) years from diagnosis. Among naxitamab patients, 10/12 remain relapse‐free post‐mAb at 1.7+ to 4.3+ (median 3.1+) years from diagnosis. Toxicity was similar with short outpatient infusions and matched that observed with these and other anti‐GD2 mAbs in older patients. These findings were reassuring given that naxitamab is dosed >2.5× higher (~270 mg/m2/cycle) than 3F8, dinutuximab, and dinutuximab beta (70‐100 mg/m2/cycle). HR‐NB in infants proved to be highly curable.
The prenatal video‐feedback intervention to promote positive parenting for expectant fathers (VIPP‐PRE): Two case studies
Authors: de Waal Noor , Alyousefi‐van Dijk Kim , Buisman Renate S. M. , Verhees Martine W. F. T. , Bakermans‐Kranenburg Marian J. 
Published: August 2022

AbstractAlthough parenting interventions including expectant fathers are scarce, they yield promising results. The Prenatal Video‐feedback Intervention to promote Positive Parenting (VIPP‐PRE) is a recently developed intervention, that is both manualized and personalized, aiming to enhance paternal sensitivity and involvement before the birth of the baby. Illustrating the intervention process, the current study presents two case studies of expectant fathers receiving VIPP‐PRE (clinical trial registration NL62696.058.17). The VIPP‐PRE program is described along with the individual dyads’ prenatal video fragments and feedback specific for each father‐fetus dyad. In addition, changes in paternal sensitivity and involvement levels are presented, as well as fathers’ and intervener's evaluation of the intervention. VIPP‐PRE promises to be a feasible short‐term and potentially effective parenting intervention for expectant fathers. Currently, a randomized controlled trial (RCT) is under review that systematically investigates the efficacy of the VIPP‐PRE. Here we aim to provide further information on the intervention process, as well as fathers’ and intervener's evaluations of this process, and the benefits of using ultrasound imaging in a parenting intervention.
Does foreign aid reduce the country's risk of OFDI? The Chinese experience
Authors: Wang Haijun , Yang Hu , Li Fengya , Zhang Min 
Published: August 2022

AbstractUsing a sample of 124 countries assisted by China from 2000 to 2019, this paper examines the impact of foreign aid on outward foreign direct investment (OFDI) and the mitigation mechanism of risk. The research finds that, first, foreign aid can significantly reduce the country risk of recipient countries, especially political risk and financial risk, and thus play a role in promoting the inflow of OFDI of donor countries, and there is a lagged effect of this role; Second, foreign aid from other countries has a negative impact on China's OFDI to recipient countries, indicating that foreign aid is nonaltruistic and exclusive; Third, the mitigation effect of foreign aid on country risk is achieved through five channels: compensation effect, synergistic effect, pioneer effect, assimilation effect, and redistribution effects.
Synthesis of nano‐sized TiO2/SiO2 cenospheres for the application in high‐performance solar thermal reflective coatings
Authors: Liu Chao Hui , Lin Hong Ping 
Published: August 2022

AbstractIn this study, we provided a designed TiO2 coating and hydrothermal treatment to synthesize nano‐sized TiO2/SiO2 cenospheres (TSCSs) with a rough surface for the application in the solar thermal reflective coating. Various functions of the TSCSs are present, the chemical composition causing significant UVA absorption, hollow interiors have high reflectance of the visible‐IR radiation, and strong scattering of incident light. In addition, the low thermal conductivity of TiO2, SiO2, and the hollow interiors makes the coatings of TSCSs achieve a good thermal insulation. The average infrared reflectance of this coating is 89.61%, and the UVA transmission is only about 22.81%.In addition, the coatings of TSCSs also demonstrate good water resistance on the glass slide due to the closure shell and rough surface to prevent water from entering the pore and cavity.
Differences in suicide risk correlates and history of suicide ideation and attempts as a function of disability type
Authors: Khazem Lauren R. , Pearlstien Jennifer G. , Anestis Michael D. , Gratz Kim L. , Tull Matthew T. , Bryan Craig J. 
Published: August 2022

AbstractBackgroundDisability status is associated with correlates of suicide risk (perceived burdensomeness, thwarted belongingness, negative future disposition, felt stigma, suicidal ideation, and suicide attempts).AimsThis study aimed to examine whether suicide‐related correlates differ significantly as a function of disability type.MethodsIndividuals with mobility and vision disabilities (N = 102) completed semistructured interviews and online‐based questionnaires. Analysis of variance/analysis of covaiance and Fisher's exact tests were conducted to examine whether mean levels of suicide‐related correlates differed significantly between individuals with blindness/low vision (n = 63) versus mobility‐related (n = 39) disabilities.ResultsNo significant between‐group differences were observed for most outcomes; however, individuals with vision disabilities reported higher mean levels of felt stigma and positive future disposition than those with mobility‐related disabilities.LimitationsThe limited representation of disabilities among participants precludes generalization to individuals with other forms of disability and the cross‐sectional design prevents inference about causality.ConclusionsInterventions targeting cognitive processes that underlie suicide risk may be applicable to people with mobility and vision disabilities.
急性電撃性紫斑病を合併し，急激な致死的経過をたどった日本紅斑熱の1例(A rare case of Japanese spotted fever complicated by acute purpura fulminans with rapid fatal course)
Authors: (Sho Jinnin) 神人 将 , (Hiroshi Fukuma) 福間 博 , (Shingo Adachi) 安達 晋吾 , (Shota Nakao) 中尾 彰太 , (Tetsuya Matsuoka) 松岡 哲也 
Published: August 2022

要旨症例は既往のない62歳の男性。登山の8日後から悪寒戦慄，発熱，倦怠感を自覚した後に前医を受診し，敗血症性ショックの診断で当院へ転院搬送となった。身体所見ではダニ咬傷を疑わせる左下腿の痂皮に加えて，両下肢の紫斑および体幹部の紅斑がみられ，血液検査では血小板減少・CRPおよび肝酵素の上昇を認めた。病歴と理学所見から日本紅斑熱を想定し，minocycline，levofloxacin，meropenemでの加療を開始した。来院直後から急激に紫斑が全身に進展するとともに，播種性血管内凝固症候群を認めたため，急性感染性電撃性紫斑病と診断した。入院20時間後に，来院時に採取した創部および血液の検体で行ったPCR検査で日本紅斑熱の診断が確定した。人工呼吸器・持続腎代替療法などの集中治療を行ったが，入院翌日に多臓器不全で死亡した。日本紅斑熱は，一般的には適切な抗菌薬治療が奏功する比較的予後の良い疾患として知られている。急性感染性電撃性紫斑病を呈する日本紅斑熱の報告は極めて稀であり，来院後早期の治療介入にも関わらず急激に致死的な経過をたどる症例を経験した。日本紅斑熱は発症後早期に治療介入しなければならない疾患であり，日本紅斑熱の危険性について広く周知し，病歴や理学所見から早期に疑うことが重要である。
難治性徐脈より心肺停止を呈し体外循環導入にて救命し得たカルバマゼピン中毒の1例(A case of carbamazepine intoxication with cardiopulmonary arrest caused by intractable bradycardia that was treated with extracorporeal circulation)
Authors: (Yoshimi Nakamichi) 中道 嘉 , (Ryo Ichibayashi) 一林 亮 , (Masayuki Watanabe) 渡辺 雅之 , (Ginga Suzuki) 鈴木 銀河 , (Hibiki Serizawa) 芹澤 響 , (Saki Yamamoto) 山本 咲 , (Mitsuru Honda) 本多 満 
Published: August 2022

要旨カルバマゼピンは抗てんかん薬で，中毒症状としてめまいや意識障害，不整脈が認められることが多い。カルバマゼピン過量服薬から徐脈性不整脈，心肺停止に至り体外循環を導入し救命した症例を経験した。症例は54歳の女性，既往に統合失調症がある。搬送当日，朝から希死念慮のためカルバマゼピンを過量服薬し，自宅で倒れているところを発見した家族が救急要請した。病院到着後に徐脈から心停止に移行した。心拍再開したが薬剤抵抗性の徐脈を認めたためVA–ECMOを導入した。入院4日目にVA–ECMOを離脱，10日目に人工呼吸器を離脱し35日目に退院となった。カルバマゼピンはナトリウムチャネルブロックの作用を有しており，催不整脈作用を有する。過量服薬時の徐脈性不整脈は治療抵抗性のため，循環不全もしくは心停止に至る症例ではVA–ECMOの導入が効果的であることが示唆された。
Australian medical imaging and world war one
Authors: Barclay Luke C. , Mandarano Giovanni 
Published: August 2022

AbstractTwenty years after the birth of medical imaging from Röntgen's 1895 discovery, military authorities understood the advantage of visualising injuries of wounded soldiers and monitoring their treatment. In World War One, medical imaging equipment was difficult to use and had to be operated in challenging environments. The most common use of x‐rays was the imaging of metallic foreign bodies such as bullets and shrapnel lodged within a soldier's body. The need to diagnose, manage war injuries and return soldiers to battle, led to medical imaging innovations including alternate means to record an image, better x‐ray tubes and an early form of tomography. Such technological advancements were made by scientists serving their respective countries. With information sourced from the Australian War Memorial archives, this paper also focusses on the experiences of an Australian wartime radiographer. This investigation demonstrates the importance, sacrifice and skills of men and women who took on the difficult task of medical imaging in the first truly world‐based conflict. It highlights how a new profession and associated technology emerged as an important tool in military medicine. Importantly, our profession's history within the context of military history should be preserved, while also honouring the legacy of individuals who contributed.
Being observed in the digital era: Conceptualization and scale development of the perception of being observed
Authors: Lefkeli Deniz , Tulan Dilan , Gürhan‐Canli Zeynep 
Published: August 2022

AbstractThis research details the development of the perception of being observed scale. Consumers may think that their actions are being observed (i.e., seen, watched, recorded, tracked) by other parties (i.e., companies, governments, people) regardless of the actual knowledge about the existence of it. We develop a 10‐item, uni‐dimensional perception of being observed scale. Following the assessments of the scale, we conduct a series of studies to test the scale's convergent, discriminant, nomological, and predictive validity. We show that technology anxiety, self‐consciousness and privacy concerns predict the perception of being observed. Further, people who experience the perception of being observed are more conservative in information disclosure.
A dual mortar embedded mesh method for internal interface problems with strong discontinuities
Authors: Ao Jun , Zhou Mozhen , Zhang Bingyin 
Published: August 2022

AbstractInternal interface problems with strong discontinuities for inclusion‐matrix systems are common and also challenging in engineering. In this work, a dual mortar embedded mesh method is proposed. An XFEM (extended finite element method) model is used for the underlying matrix, which can then be meshed without considering internal boundaries. The inclusions are treated by conventional FEM (finite element method) model. The FEM‐XFEM coupling is treated by the dual mortar method, which uses the XFEM side to carry the Lagrange multiplier for imposing inclusion‐matrix contact constraints. The present method is first validated by contact patch tests as well as bending tests and then applied to simulate strong discontinuities arising from bolt‐rock and pile‐soil interactions. The numerical results indicate that the present method is capable of simulating the internal interface problems with high accuracy, computational efficiency as well as mesh convenience.
Thermal buckling analysis of tapered laminated composite beam: Numerical and experimental investigation
Authors: Arumugam Ananda Babu , Rajendra Chandole Onkar , Edwin Sudhagar P. , Rajamohan Vasudevan , Kumbhar Surajkumar G. , Perumal Anbumani 
Published: August 2022

AbstractThe present study focuses on the numerical modeling of the thermal buckling behavior of tapered laminated composite beams validated by experimentation. Lagrange's energy‐based governing differential expression was derived utilizing classical laminated plate theory and higher‐order shear deformation theory to analyze the tapered composite beam's thermal buckling property. The uniform temperature rise environment is employed to estimate the critical buckling temperature of the tapered laminated composite beam. The obtained results from the numerical approaches were validated with the experimental results and the previous results obtained from the literature associated with the fundamental frequencies of the structure and critical buckling temperature. The parametric study was incorporated in this present work to investigate the influence of the structural parameters and the geometrical parameters like taper angle, ply orientation, aspect ratio, and boundary constraints of the beam.
Gauging secondary school students' terrorism‐related resilience in the Sahel region of Burkina Faso: A quantitative study
Authors: Bene Konabe 
Published: August 2022

AbstractThis study appraised male and female students' levels of terrorism‐related resilience, its effect on emotion and achievement, and assessed gender differences. The sample size was 180 junior and high school students of which 66 females (36.3%) and 114 males (62.6%) in the Sahel. Participants' ages ranged from 13 to 24 with a mean of 17.1 (SD = 2.04). Descriptive, multiple linear regression, and t‐test analyses were implemented to test for the size of resilience, its effects on students' emotional health and achievement, and to assess gender differences. Students had low level of resilience. Academic performance did not predict resilience, though regression analyses were statistically significant. Furthermore, no gender differences were found. Low level of resilience implies that students possess high level of difficulties in coping with terrorism. Psychological services are suggested to help secondary school students cope with the adverse effects of the stated violence.