bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular docking studies of tyrosine kinase inhibitors: Exemplified protocol to advance pharmaceutical education in medicinal chemistry
Authors: Gani Ibtihal Haitham , Al-Obaidi Zaid 
Published: October 2022

Background: One of the essential goals of pharmacy education is to extend professional learning to pharmacists, pharmacy students and educators. Medicinal chemistry is a major component of this professional learning. Nowadays, computer-aided drug design (CADD) is considered a cornerstone in drug discovery platforms. However, this computational drug design is not crystal-clear to pharmacy students and pharmacists. In this study, a molecular docking process was established to advance pharmaceutical education in the medicinal chemistry field.
Method: CADD is available in the syllabus of Iraqi pharmacy schools however the software packages are not available for the students to practice the docking process. Five different compounds were designed and docked by employing the Genetic Optimisation of Ligand Docking (GOLD) software and the scores were recorded.
Results: Pharmacy students would use this exemplified docking to enhance their understanding of the medicinal chemistry module.
Conclusion: This educational docking study was successfully performed to advance the pharmacy education.
Are men’s happiness and life satisfaction linked to why men die earlier than women? A panel study from 1981 to 2020 in 102 countries
Authors: Ngamaba Kayonda Hubert , Kandala Ngianga-Bakwin , Ilenda Francois Batuyekula , Mupolo Perseverante Kawata 
Published: October 2022

The motivation for happiness research rather than GDP is becoming important to the role of many governments across the globe. When people are asked to list the key characteristics of a good life, they are more likely to include happiness, health, living well and longer. This study investigates whether factors that predict men’s happiness and life satisfaction explain why men die earlier than women. The present research analyses data (N=426,452; 51.90% females) collected by the World Value Survey from 1981 to 2020 in 102 countries, and from six continents. A multilevel random-effects regression analysis was conducted in which individuals were nested by countries. We investigated variations across nations, country-level of development, and geographical regions. Men were slightly less happy and less satisfied with their lives compared to women. State of health, household’s financial satisfaction, freedom of choice, family importance, and being married were positively associated with happiness/life satisfaction. In contrast, being men, being in a low-income household, or being unemployed were negatively associated with happiness/life satisfaction. Unemployed men and men who were living in Africa or the Middle East regions were less satisfied with their lives compared to women. The excess mortality burden on men is due to a mix of biological, behavioural, and social factors. Happy people may live longer because of underlying factors such as health status, household financial satisfaction, and social connections. Policies targeting men’s health and social connections are needed.
A Novel and Low-Cost Visual Aid for Retinitis Pigmentosa Patients to Improve Peripheral Vision Loss
Authors: Venu Ganesh , Stafford Susanne 
Published: October 2022

Retinitis pigmentosa (RP) is a genetic eye disorder that affects 1 in 3000-8000 people worldwide and causes the deterioration of the light-sensitive pigmented layer of the eye. Typical symptoms include night blindness and subsequently decreasing visual fields. Unfortunately, the specific cause of RP is not known and there is no cure. The disease is currently managed by expensive visual aids ranging from $3000 to $6000. This creates a need to develop affordable glasses for the common individual. In this study, 3D printed glasses were developed that enhanced the peripheral vision of the mocking RP patient (student researcher) utilizing external smartphone wide-angle lenses. To test different levels of tunnel vision, 3D printed circular discs with hole sizes of 1 mm, 3 mm, 5 mm, 7 mm, and 9 mm were created representing the varying severity of vision loss in RP patients. These discs were inserted in the frames of 3D printed glasses with and without wide-angle lenses. The student researcher validated these glasses on a bullseye model and observed a doubling in the visual field. Three replication data was collected comparing normal vision and different levels of RP (using tunnel vision discs) with and without the wide-angle lens glasses. Regression analysis of data generated from a Monte Carlo Simulation and T-Test procedure further confirmed a statistically significant increase in the visual field utilizing wide-angle lens glasses. Thus, a cost-effective visual aid ($20) was developed by the student researcher to improve peripheral vision and break socio-economic barriers for RP patients.
Askeri Teknik Sınıflar Tarihi İçin Önemli Bir Kaynak: Fen Kıtaâti Mecmuası (Fen Kıtaları Mecmuası/Fen Kıtaları Dergisi)
Authors: AS Efdal , BACANLI Hakan 
Published: October 2022

Türkiye’de süreli askerî yayınların tarihi, 1864 yılında yayınlanmaya başlayan Ceride-i Askeriye adlı gazeteye kadar gitmektedir. Bu tarihten, Osmanlı Devleti’nin sona erdiği tarihe kadar, özellikle kara ve deniz birliklerine yönelik olarak, çeşitli resmî süreli askerî gazeteler ve dergiler yayınlanmıştır.
Cumhuriyet dönemine gelindiğinde, söz konusu gazete ve dergilerin bir kısmının yayınlanmaya devam ettiği görülmektedir. Bunların dışında, 1925 yılından itibaren, Türk Silahlı Kuvvetlerinde hem mevcut personelin mesleki bilgilerini artırmak hem de yeni katılan personele kendi sınıfıyla ilgili olarak teknik bilgiler vermek amacıyla askerî sınıflara mahsus dergiler çıkarılmaya başlanmıştır. Piyade, topçu ve süvari gibi ordunun üç asli sınıfına (sunûf-ı selase) ait dergilerin yanı sıra, o dönemde “Fen Kıtaâti” adıyla anılan muhabere, istihkâm ve demiryol sınıflarına özgü bir derginin de o dönemde yayınlanmış olduğu görülmektedir. Çalışmada, Fen Kıtaâti Mecmuası adıyla yayın hayatına başlayan ve isim değişiklikleriyle, Ekim 1948 tarihine kadar yayınlanmaya devam eden dergi hakkında ayrıntılı bilgi verilecektir.
Pengaruh Edukasi Kesehatan Tentang Pencegahan Penyakit Covid-19 Terhadap Perubahan Tingkat Pengetahuan Mahasiswa Keperawatan Universitas Kristen Indonesia Jakarta Timur
Authors: Anggraini Yanti 
Published: October 2022

Abstrak
Latar Belakang Penyakit Covid-19 merupakan penyakit baru yang disebabkan oleh Severe Acute Respiratory Syndrome Corona Virus- 2 dimana penyakit ini telah menjadi pandemik dan harus diwaspadai karena tingkat penularan relatif cepat. Karena tugas yang menumpuk, mahasiswa berkumpul bebas dan tidak melakukan jaga jarak dalam mengerjakan tugas, sehingga mahasiswa mudah terjangkit penyakit Covid-19. Diperlukan edukasi tentang pencegahan penyakit Covid-19 ke mahasiswa. Tujuan penelitian ini adalah untuk mengetahui pengaruh edukasi kesehatan terhadap tingkat pengetahuan mahasiswa perawat.
Metode Metode penelitian kuantitatif dengan menyebarkan kuesioner pre dan post sebelum dan sesudah intervensi edukasi kesehatan tentang pencegahan penyakit Covid-19 sebanyak 43 mahasiswa Prodi DIII Keperawatan Universitas Kristen Indonesia Tingkat 1,2 dan 3.
Hasil Hasil penelitian menunjukan bahwa adanya perbedaan peningkatan tingkat pengetahuan mahasiswa perawat sebelum dan sesudah intervensi pemberian edukasi tentang penyakit Covid-19 di Universitas Kristen Indonesia dengan P-Value = 0,029 (P < 0,05). tidak ada hubungan antara usia terhadap perubahan tingkat pengetahuan mahasiswa perawat dengan P-Value = 0,608 (<0,05). Tidak ada hubungan antara Jenis Kelamin terhadap perubahan tingkat pengetahuan mahasiswa perawat dengan P-Value = 0,156. Tidak ada hubungan antara Pendidikan Terakhir terhadap perubahan tingkat pengetahuan mahasiswa perawat dengan P-Value = 0,182. Tidak ada hubungan antara Tingkat Semester terhadap perubahan tingkat pengetahuan mahasiswa perawat dengan P-Value = 0,700.
Kesimpulan Edukasi kesehatan mempengaruhi perubahan tingkat pengetahuan tentang pencegahan penyakit Covid-19 sebelum dan sesudah intervensi. Disarankan agar institusi pendidikan atau tenaga kesehatan sering memberikan edukasi kesehatan tentang pencegahan penyakit Covid-19 ke mahasiswa jurusan lain, kampus lain bahkan masyarakat umum.
Kata Kunci: Edukasi, Mahasiswa, Covid-19
ANALISIS FAKTOR DAN SITUASI YANG BERPENGARUH TERHADAP PERILAKU PREVENTIF PENYEBARAN COVID-19 PADA ANAK USIA PRESCHOOL DAN USIA SEKOLAH DI DUSUN PANDANSATI KECAMATAN PONCOKUSUMO KABUPATEN MALANG
Authors: Pradikatama Prihanto Yafet , Maria Prieska Putri Panglipur Ati  , Nadia Oktiffany Putri  
Published: October 2022

ABSTRAK
Pandemi Covid-19 menyebabkan beberapa gangguan fungsi kehidupan pada anak prasekolah dan sekolah antara lain gangguan fisik, dan gangguan perkembangan diantaranya terhambatnya aktifitas fisik, sosialisasi, kognitif, emosi, serta kepribadian anak, hingga dapat mengganggu masa depan anak sebagai dampak jangka panjangnya. Hal tersebut harus diidentifikasi situasi serta faktornya agar dapat segera dilaksanakan upaya pencegahan penyebaran Covid-19. Tujuan dari penelitian ini adalah untuk mengetahui Situasi dan faktor-faktor yang mempengaruhi perilaku pencegahan Covid-19 pada anak usia pra-sekolah dan sekolah di desa Pandansari. Penelitian ini merupakan penelitian kuantitatif non eksperimental dengan desain cross-sectional. Penelitian dilaksanakan pada anak usia 4-12 tahun di dusun Pandansari, Kabupaten Malang dengan teknik pengambilan sampel secara random sampling. Instrumen penelitian menggunakan kuesioner tentang kesehatan umum (ghq-28); kuesioner pengetahuan tentang pencegahan COVID-19; kuesioner kepercayaan terhadap profesi keperawatan; kuesioner sikap terhadap COVID-19; kuesioner persepsi risiko infeksi COVID-19; kuesioner tingkat keparahan yang dirasakan dari COVID-19; kuesioner kemanjuran diri yang dirasakan dari pencegahan COVID-19; kuesioner ketahanan; kuesioner dukungan sosial yang dirasakan; kuesioner aksesibilitas layanan kesehatan serta kuesioner perilaku pencegahan COVID-19. Pengambilan data dilakukan dengan metode wawancara atau laporan dari orang tua responden. Analisis data menggunakan SEM. Hasil penelitian ini adalah Goodness of Fit pada SEM hasil dari pengolahan AMOS diperoleh nilai c2 (chi-square)/ df sebesar 12,91 cukup besar (≤ 3) antar variabel yang berarti model belum fit. Selanjutnya, nilai NFI sebesar 0,912 (0,90-0,95), nilai TLI sebesar 0,887 (≥0,90), nilai CFI sebesar 0,918 (≥0,90), dan nilai GFI sudah cukup tinggi sebesar 0,996 (≥0,90) sehingga menunjukkan bahwa model hipotesa sudah fit/ sesuai. Adapun nilai factor loading pada masing-masing konstruk sudah baik (≥ 0,50). Faktor Predisposisi, factor penguap, factor pemungkin berpengaruh positif terhadap Perilaku Pencegahan Covid-19. Nilai Standardize estimates yang dihasilkan adalah 0,26 (p < 0.01) yang menujukkan terdapat hubungan yang signifikan antara Faktor Predisposisi Perilaku Pencegahan Covid-19. Nilai Standardize estimates yang dihasilkan adalah 0,26 (p < 0.01) yang menujukkan terdapat hubungan yang signifikan antara Faktor Predisposisi terhadap Perilaku Pencegahan Covid-19.
Kata Kunci : anak, pra-sekolah, sekolah, pencegahan penyebaran, covid-19
Identifikasi Aspek Dominan Illness perception pada Pasien Diabetic Foot Ulcer
Authors: Tjomiadi Cynthia Eka Fayuning , Manto Onieqie Ayu Dhea 
Published: October 2022

Abstract

Background: Diabetic Foot Ulcer (DFU) is a microvascular complication in diabetes mellitus which allows it to be prevented through multidisciplinary collaboration that involves the active participation of patients, namely the application of self-care behavior. But unfortunately self-care behavior itself is still relatively low. Many studies have identified the relationship between knowledge and behavior to prevent LKD, but knowledge is not the only factor that influences this. Illness perceptions is a person's point of view that plays an important role in behavior and decision making. So, it is necessary to identify the dominant aspects of illness perceptions in DFU patients.
Objective: This study aims to identify the dominant aspects of illness perceptions on LKD patients.
Methods: This research design uses a descriptive quantitative method with data collection through a questionnaire survey.
Results: This study used 43 samples after being identified there were 2 dominant aspects of illness perception in LKD patients, namely aspects of treatment control and coherence.
Conclusion: The higher the patient's confidence in the treatment control and understanding of the disease, the better the foot care will be.

Keywords: Diabetic Foot Ulcer, Dominant aspect, illness perceptions
Pendampingan Remaja SMKN 5 Surabaya Terhadap Bahaya Penyalahgunaan NAPZA dan HIV/Aids
Authors: Kusumawardani Eva Flourentina , Rimonda Rubi , Paradhiba Meutia , Siahaan Perry Boy Chandra , Saputra Firman Firdauz , Fadillah Mardi , Putra Onetusfifsi 
Published: October 2022

Adolescence is a period of transition and experiencing rapid development ranging from physical, psychological and intellectual organs so that it requires good and supportive assistance to properly recognize these changes. Management of psicology which is emotions in adolescents who are not directed will cause adolescents to enter into risky behavior including drug abuse and risky sexual behavior. Increasing awareness of adolescents about the dangers of drug abuse, health problems caused by drug abuse and risky sexual behavior that causes sexually transmitted infections (STIs) including HIV and Aids through peer educators was urgently needed by adolescents. The target of the service was the youth of Civil Vocational High School (SMKN) 5 Surabaya and in its implementation it worked with the youth community who are members of the SCARFS (School and Communities Caring for HIV & AIDS) community 30 people. The methods used in this service activity were lectures / counseling, discussions, questions and answers (QnA) and evaluations using pre and post test questionnaires. The results of the service activities carried out received good enthusiasm from the participants. The enthusiasm of the participants was during the case discussion session, participants asked an average of 4 questions to the facilitator and there was an increase in knowledge about drugs and HIV/Aids.
Children’s satisfaction and survival rate of fiber-reinforced space maintainer versus band and loop space maintainer in children with premature loss of maxillary primary first molar
Authors: EL-Awady Ahmed Akram , Badreldin Hamdy Mahmoud 
Published: October 2022

Background: Band and loop space maintainer (BLSM) are well tolerated and long-lasting appliances, but it comes with several drawbacks, including longer lab times, more frequent cement loss dislodgements, longer visits, and the inability to avoid the rotation or tilting of neighboring teeth. These limitations motivate the search for alternative appliance such as fiber-reinforced space maintainers. Aim of the study: Evaluation of children’s satisfaction and survival rate of fiber-reinforced space maintainer versus band and loop space maintainer in children with premature loss of maxillary primary 1st molar. Materials and Methods: Thirty patients, randomly divided into two groups (n=15). BLSM group: which included (15) patients who receive band and loop space maintainer. FRSM group: which included (15) patients who were received fiber-reinforced space maintainer. The patients were evaluated for satisfaction based on Likert -type scale and survival rate. Results: The FRSM group showed a higher satisfaction score than BLSM group. For survival rate the fiber-reinforced space maintainers showed a greater success rate than band and loop space maintainers. Conclusions: The FRSM can be used as an alternative to BLSM regarding clinical performance and patient’s satisfaction in children with premature loss of maxillary 1st primary molars.
Survei keterampilan motorik dasar peserta didik usia 10-11 tahun selama masa pandemi covid-19
Authors: Setyawan Aditya Bagus , Setiawan Irwan , Yuliawan Dhedhy , Pratama Budiman Agung 
Published: October 2022

Penelitian bertujuan untuk mengetahui lebih jauh penerapan aktivitas fisik baik buruknya pada anak usia sekolah dan pengaruh pendidikan jasmani terhadap keterampilan motorik halus pada anak. Adapun penelitian bertujuan untuk menentukan aktivitas fisik keterampilan motorik dasar pada peserta didik kelas V di SDN Tugu Kec. Mantub Kab. Lamongan selama periode pandemi Covid-19. Penelitian ini menggunakan pendekatan kuantitatif deskriptif. Subyek adalah anak kelas 5 di SDN Tugu Kecamatan Mantup Kabupaten Lamongan sebanyak 10 peserta didik (L: 6; P: 4). Instrumen menggunakan Test of Gross Motor Development, second edition (TGMD-2). Analisis data yang digunakan adalah deskriptif. Hasilnya menunjukkan aktivitas fisik terhadap fundamental motorskill peserta didik kelas V pada kategori rata-rata dengan rentang nilai GMQ Standard skor 90-110 pada Persentil skor 25-75.
Analisis tingkat self confidence pada atlet sepatu roda
Authors: Suryawati Suryawati , Brustiando Rizky , Himawanto Wasis , Pratama Budiman Agung 
Published: October 2022

Penelitian ini memiliki tujuan untuk menganalisis tingkat self confidence atlet pada klub sepatu roda FIST di Tulungagung, dengan jumlah sampel 13 orang atlet. Metode yang digunakan dalam penelitian ini adalah deskriptif kuantitatif non eksperimen. Instrumen dalam penelitian ini berupa angket tertutup dan skala yang digunakan adalah skala likert, dan mendapatkan data dari angket yang telah disebar kepada sampel. Hasil penelitian menunjukkan tingkat self-confidence atlet sepatu roda FIST di Tulungagung berdasarkan 2 faktor yang mempengaruhi tingkat self-confidence yaitu, faktor eksternal memperoleh kategori “tinggi” sebanyak 7 atlet (54%) dan faktor internal memperoleh kategori “tinggi” sebanyak 8 atlet (62%) dengan rata – rata 58 %. Berdasarkan hasil penelitian tersebut dapat disimpulkan bahwa atlet sepatu roda FIST Tulungagung memiliki tingkat self-confidence tinggi. Pernyataan tersebut dapat dimaknai bahwa atlet sepatu roda FIST Tulungagung memiliki keyakinan/percaya diri dan sportif dalam berlatih maupun bertanding untuk meraih prestasi.
Analisis kondisi fisik atlet karate
Authors: Mustofa Ade Ikamala , Sahri Sahri 
Published: October 2022

Kondisi fisik mempengaruhi atlet pada saat latihan maupun saat pertandingan. Oleh sebab itu penelitian berikut ini bertujuan untuk menganalisis kondisi fisik dari atlet-atlet karate Inkanas Dojo Yondan Kabupaten Lampung Tengah. Penelitian ini ialah penelitian kuantitatif deskriptif. Instrument penelitian yan digunakan ialah 6 item tes, yaitu Push up 60 detik, Lari sprint 30m, shuttle run, standing board jump, MFT, dan V-sit and reach test. Sampel penelitian ini yaitu atlet Karate Inkanas Dojo Yondan Lampung Tengah yang berjumlah 10 orang. Penelitian ini menggunakan teknik purposive sampling. Hasil penelitian pada atlet karate Inkanas Dojo Yondan menunjukkan bahwa terdapat 8 atlet (80%) dalam kategori kurang sekali, 0 atlet (0%) dalam kategori kurang, 2 atlet (20%) dalam kategori cukup, 0 atlet (0%) dalam kategori baik, dan 0 atlet (0%) dalam kategori baik sekali. Dari data diatas, frekuensi terbanyak adalah kategori kurang sekali, yaitu 8 atlet (80%). Hingga dapat ditarik kesimpulan bahwa kondisi fisik atlet karate Inkanas Dojo Yondan adalah kurang sekali. Penelitian ini dapat dijadikan acuan sebagai pembuatan program latihan yang sesuai dan terfokus pada unsur-unsur kondisi fisik pada cabang olahraga karate.
Effect of Family Involvement and Corporate Governance on Dividend Policy: A Study of Non-Financial Listed Firms in Morocco
Authors: Toumi Said , Su Zhan 
Published: October 2022

Current research on the determinants of dividend policy has focused on the study of developed countries, while
research on emerging countries remains limited. The objective of this research is to study the effect of the
involvement of the family firm on dividend policy. This paper uses Ordinary Least Squares regression, we
analyzed data for Moroccan nonfinancial firms listed on the Casablanca Stock Exchange over the period
2015-2017. The results of this paper show that family firm pay less dividends than non-family firms. Thus,
ownership concentration and firm size influence dividend policy, unlike the composition of the board of
directors, which doesn&rsquo;t influence it. Our paper contributes to broaden our understanding of the effect of the
family firm on dividend policy in one of the emerging countries. It is suggested that the characteristics of
corporate ownership determine the share of profits to be distributed, not to say dividend policy, since
concentration of ownership limits the power of minority shareholders to make their voices heard. Despite the
presence of laws protecting minority shareholders, their room for maneuver remains limited. Our paper
enriches the existing literature on the family firm dividend policy by studying the Moroccan context. The results
show that family ownership and family CEO involvement do not have the same influence on the dividend policy
of family firms, but it depends on the context. Our paper also provides relevant information for practitioners
regarding dividend policy in Moroccan family firms.
Analisis Manfaat Program Kartu Prakerja di Kecamatan Biau Kabupaten Buol
Authors: Abd Rahman Alatas  , Moh Sabran A  , Imas Nurfauzia D. Hidayat  
Published: October 2022

Penelitian ini bertujuan untuk mengetahui bagaimana persepsi masyarakat mengenai manfaat program Kartu Prakerja di Kecamatan Biau, Kabupaten Buol. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Sumber data primer diperoleh melalui wawancara mendalam. Teknik analisis data yang digunakan yaitu menggunakan teori dari Miles dan Huberman dengan cara mengumpulkan data, mereduksi data, menyajikan data dan menarik kesimpulan, serta verifikasi data dengan menggunakan teknik triangulasi. Penelitian ini menghasilkan kesimpulan bahwa manfaat insentif oleh penerima manfaat program Kartu Prakerja di Kecamatan Biau, Kabupaten Buol telah dimanfaatkan dengan baik dan sesuai dengan apa yang menjadi harapan pemerintah dalam Peraturan Presiden Nomor 76 Tahun 2020 tentang Pengembangan Kompetensi Kerja Melalui Program Kartu Prakerja, tetapi dalam prakteknya masih memiliki kendala berupa minimnya kontrol pemerintah daerah yang membuka peluang bagi calo untuk mengambil keuntungan dari insentif. Sedangkan, pemanfaatan pelatihan pada program Kartu Prakerja sendiri secara keseluruhan belum berjalan optimal karena minimnya ketertarikan peserta untuk meningkatkan kompetensi melalui pelatihan yang ditawarkan, ditambah dengan keterlibatan calo yang menutup kesempatan peserta merasakan ataupun belajar melalui pelatihan yang seharusnya mereka ikuti. Sehingga, diperlukannya kontrol serta terobosan dari pemerintah agar keputusan masyarakat untuk menggunakan calo dapat diminimalisir dan menjamin bahwa masyarakat penerima manfaat program telah tepat sasaran.