bluuebunny/crossref_metadata_2025_split huggingface dataset:
Time‐Lapse Record of an Earthquake in the Dry Felsic Lower Continental Crust Preserved in a Pseudotachylyte‐Bearing Fault
Authors: Mancktelow Neil S. , Camacho Alfredo , Pennacchioni Giorgio 
Published: March 2022

AbstractThe mechanisms of earthquake rupture in lower continental crust, below the usual frictional‐viscous transition, remain uncertain. In addressing this problem, the study of pseudotachylyte (quenched frictional melt produced during seismic fault slip) and related structures from deeply exhumed rocks can provide direct observational constraints. A felsic granulite from the Musgrave Ranges (central Australia) exceptionally preserves pristine microstructures spatially related to a pseudotachylyte. This sample remained dry, without introduction of hydrous fluids, during pseudotachylyte development and subsequent exhumation. It was therefore unaffected by alteration and metamorphic re‐equilibration. Fractures in the damage zone developed asymmetrically to either side of the pseudotachylyte and are marked by new, randomly oriented quartz, feldspar, and garnet grains. Pulverization of garnet occurred locally between intersecting fractures with powder injected into dilatant fractures in a quartz inclusion within the garnet host. Injection of pulverized material can explain the growth of new, compositionally different minerals (quartz, feldspar, kyanite, ilmenite, magnetite, and rutile) along dilatant fractures developed in a short‐lived seismic event. The pseudotachylyte contains only clasts of quartz, suggesting an unusually high melting temperature. The sequentially developed microstructures provide a time‐lapse record of thermomechanical processes during a single earthquake event, including initial rupture propagation with associated off‐fault damage and local pulverization during very dynamic fluctuations in the local stress field; frictional heating and eventual melting during fault slip; flow and injection of melt; and rapid solidification (quenching) and crystallization of new minerals. This occurred under lower continental crustal conditions of ca. 650°C and 1.2 GPa about 550 Myrs ago.
Modification of Internal Wave Generation and Energy Conversion in the Nearshore Due To Tide‐Tide and Tide‐Wind Interactions
Authors: Omidvar Sorush , Fagundes Matheus , Woodson C. Brock 
Published: March 2022

AbstractInternal wave generation due to semi‐diurnal tides (M2) through the acceleration of barotropic tidal flow over sloped topography has received considerable attention over the past several decades. However, the contribution of other tidal constituents and their interactions with M2 have not been as extensively evaluated. Moreover, on the inner shelf, the cross‐shore wind, which is often neglected in the energy conversion studies, dominates the cross‐shore transport and can also affect the energy conversion process. This study addresses this gap by including a diurnal (K1) tidal component and a shoreward diurnal sea breeze in an idealized model of southern Monterey Bay as it represents a highly stratified system that experiences active surface and internal tides. Our simulations demonstrate the role of the K1 tide and its interaction with M2, which is constructive and insensitive to the initial phase lag. Wind‐induced perturbations grow with the wind speed and enhance M2 conversion. On the other hand, the wind interaction with the K1 and M2K1 tides highly depends on the timing with constructive (destructive) conversion occurring when the shoreward wind intensifies during the ebb (flood) tide. Interactions among tides and winds lead to highly variable conversion rates, changes in timing and location of peak conversion, and a range of internal wave frequencies. Such a dynamic alone can be responsible for the complex internal wave environments often observed in the nearshore.
Climatology of Dust Deposition in the Adriatic Sea; a Possible Impact on Marine Production
Authors: Mifka Boris , Telišman Prtenjak Maja , Kuzmić Josipa , Čanković Milan , Mateša Sarah , Ciglenečki Irena 
Published: March 2022

AbstractAtmospheric mineral dust deposition plays an important role in providing nutrients to marine ecosystems. In this study, the climatology of dust deposition in the Adriatic Sea area was determined for the first time based on Modern‐Era Retrospective Analysis for Research and Applications, version 2 reanalysis from 1989 to 2019. The annual cycle of deposition exhibits two maxima: a stronger maxima in March–April and a weaker maxima in November. Wet deposition is a dominant process with a relative contribution to overall deposition from 67.35% to 88.53%. Deposition hot spots are along the Montenegrin coast and Otrant. The average contribution of dust deposition events (DDEs) is 16.5% (60.2 dy yr−1), with the strongest deposition during 1999–2009 and a positive trend in deposited mass during the study period. The effect of dust deposition on primary production is observed by a high level of oxygen saturation up to 250% (usually it is lower, up to 150%) in the stratified middle water layer (5–8 m) of the central Adriatic marine system (Rogoznica Lake) during an intense wet deposition episode. Such extreme values of oxygen saturation can be taken as an indication of biological activity related to an increase in phytoplankton abundance and activity, diatoms in particular.
Rockfall Activity Rates Before, During and After the 2010/2011 Canterbury Earthquake Sequence
Authors: Massey C. I. , Olsen M. J. , Wartman J. , Senogles A. , Lukovic B. , Leshchinsky B. A. , Archibald G. , Litchfield N. , Dissen R. Van , de Vilder S. , Holden C. 
Published: March 2022

AbstractThe effects of strong ground shaking on hillslope stability can persist for many years after a large earthquake, leading to an increase in the rates of post earthquake land sliding. The factors that control the rate of post‐earthquake land sliding are poorly constrained, hindering our ability to reliably forecast how landscapes and landslide hazards and risk evolve. To address this, we use a unique data set comprising high‐resolution terrestrial laser scans and airborne lidar captured during and after the 2010–2011 Canterbury Earthquake Sequence, New Zealand. This earthquake sequence triggered thousands of rock falls, and rock and debris avalanches (collectively referred to as “rockfall”), resulting in loss‐of‐life and damage to residential dwellings, commercial buildings and other infrastructure in the Port Hills of Christchurch, New Zealand. This unique data set spans 5 years and includes five significant earthquakes. We used these data to (a) quantify the regional‐scale “rockfall” rates in response to these earthquakes and the postearthquake decay in rockfall rates with time; and (b) investigate the site‐specific factors controlling the location of seismic and nonseismic rockfalls using frequency ratios and logistic regression techniques. We found that rockfall rates increased significantly in response to the initial earthquake that generated the strongest shaking in the sequence—The MW 6.2 22 February 2011 event—Compared to the long‐term background rates derived from the dating of pre‐2010 talus piles at the toe of the slopes. Non seismic rockfall rates also increased immediately after the 22 February 2011 earthquake and decayed with time following a power‐law trend. About 50% of the decay back to the pre‐earthquake rockfall rates occurred within 1–5 years after the 22 February 2011 earthquake. Our results show that the short‐term decay in rockfall rates over time, after the initial earthquake, was attributed to the subsequent erosion of seismically damaged rock mass materials caused by environmental processes such as rain. For earthquake‐induced rockfall at the regional‐scale, the peak ground accelerations is the most significant variable in forecasting rockfall volume, followed by the relative height above the base of the slope. For both earthquake and non‐seismic conditions at the site‐specific scale, the probability of rockfall increases when the adjacent areas have failed previously, indicating that accrued damage preconditions localized areas of the slope for subsequent failure. Such preconditioning is a crucial factor driving subsequent rockfalls; that is, future rockfalls are likely to cluster near areas that failed in the past.
Improving Wet and Dry Deposition of Aerosols in WRF‐Chem: Updates to Below‐Cloud Scavenging and Coarse‐Particle Dry Deposition
Authors: Ryu Young‐Hee , Min Seung‐Ki 
Published: March 2022

AbstractWet and dry depositions of aerosols in WRF‐Chem are revisited and updated based on recent observational findings. Traditionally, in‐cloud scavenging was thought to play a more dominant role in aerosol wet removal than below‐cloud scavenging. However, recent field measurements indicated a considerable contribution of below‐cloud scavenging of 50%–60% to total wet deposition. In contrast, the simulated contribution of in‐cloud scavenging in the previous version of WRF‐Chem was too large, exhibiting 88%–95%, likely due to the binary representation of cloud fraction. To reduce the model bias, this study adopts a continuous‐type cloud fraction and implements a semi‐empirical below‐cloud scavenging parameterization. Simulation results with the new scheme show that the contribution of below‐cloud (in‐cloud) scavenging is increased to 63%–66% (decreased to 34%–37%), well capturing the observational estimates. The magnitude of total wet deposition is increased by 18.2% for SO4, 7.16% for NO3, and 14.8% for NH4, showing better agreements with observations particularly for SO4 and NH4 deposition. The increased wet removal with the new scheme reduces and so better reproduces surface PM2.5 and PM10 concentrations, which is also partly attributed to the increased contribution of below‐cloud scavenging. It is found that dry deposition velocity in the previous version was too high for coarse mode particles when friction velocity is large, which underestimates surface PM10 concentration. The updated dry deposition scheme that is constrained by observations effectively improves PM10 performance by reducing the dry deposition velocity for coarse mode particles.
Liquid Breakthrough Time in an Unsaturated Fracture Network
Authors: Zhou Zexiong , Yang Zhibing , Xue Song , Hu Ran , Chen Yi‐Feng 
Published: March 2022

AbstractWe present an experimental and theoretical study of unsaturated flow in discrete fracture networks. The focus is on the breakthrough time of infiltrating liquid through the fracture networks as well as the spatial distribution of local flow status under a wide range of flow rates. Through visualized experiments, the fluid motion in the fracture network is recorded and analyzed, and gravity‐driven preferential pathways are observed. The location of the breakthrough path is found to be insensitive to the flow rate under the single‐inlet flow condition. Based on analogy with slug migration in a single fracture and considering liquid accumulation due to the capillary barrier effect at the fracture intersections, we propose a theoretical model of liquid breakthrough time through an initially dry fracture network. The theoretical predictions are found to be in excellent agreement with the experimental results. Using the model, we analyze the relative contribution of times needed for liquid migration and for local liquid accumulation to the breakthrough time. We also find that the spatial distribution of local flow status at the steady‐state varies significantly with the flow rate. The improved understanding and the proposed model are of significance for predicting the time required for a fluid/contaminant to reach a certain depth in unsaturated fractured media, and may provide new physical insights on the complex unsaturated flow dynamics.
On the Estimation of Potential Evaporation Under Wet and Dry Conditions
Authors: Tu Zhuoyi , Yang Yuting 
Published: March 2022

AbstractPotential evaporation (EP) is an important concept that has been extensively used in hydrology, climate, agriculture and many other relevant fields. However, EP estimates using conventional approaches generally do not conform with the underlying idea of EP, since meteorological forcing variables observed under real conditions are not necessarily equivalent to those over a hypothetical surface with an unlimited water supply. Here, we estimate EP using a recently developed ocean surface evaporation model (i.e., the maximum evaporation model) that explicitly acknowledges the inter‐dependence between evaporation, surface temperature (Ts) and radiation such that is able to recover radiation and Ts to a hypothetical wet surface. We first test the maximum evaporation model over land by validating its evaporation estimates with evaporation observations under unstressed conditions at 86 flux sites and found an overall good performance. We then apply the maximum evaporation model to the entire terrestrial surfaces under both wet and dry conditions to estimate EP. The mean annual (1979–2019) global land EP from the maximum evaporation model (EP_max) is 1,272 mm yr−1, which is 11.2% higher than that estimated using the widely adopted Priestley‐Taylor model (EP_PT). The difference between EP_max and EP_PT is negligible in humid regions or under wet conditions but becomes increasingly larger as the surface moisture availability decreases. This difference is primarily caused by increased net radiation (Rn) when restoring the dry surfaces to hypothetical wet surfaces, despite a lower Ts obtained under hypothetical wet conditions in the maximum evaporation model.
Slab-derived devolatilization fluids oxidized by subducted metasedimentary rocks
Authors: Ague Jay J. , Tassara Santiago , Holycross Megan E. , Li Ji-Lei , Cottrell Elizabeth , Schwarzenbach Esther M. , Fassoulas Charalampos , John Timm 
Published: March 2022

AbstractMetamorphic devolatilization of subducted slabs generates aqueous fluids that ascend into the mantle wedge, driving the partial melting that produces arc magmas. These magmas have oxygen fugacities some 10–1,000 times higher than magmas generated at mid-ocean ridges. Whether this oxidized magmatic character is imparted by slab fluids or is acquired during ascent and interaction with the surrounding mantle or crust is debated. Here we study the petrology of metasedimentary rocks from two Tertiary Aegean subduction complexes in combination with reactive transport modelling to investigate the oxidative potential of the sedimentary rocks that cover slabs. We find that the metasedimentary rocks preserve evidence for fluid-mediated redox reactions and could be highly oxidized. Furthermore, the modelling demonstrates that layers of these oxidized rocks less than about 200 m thick have the capacity to oxidize the ascending slab dehydration flux via redox reactions that remove H2, CH4and/or H2S from the fluids. These fluids can then oxidize the overlying mantle wedge at rates comparable to arc magma generation rates, primarily via reactions involving sulfur species. Oxidized metasedimentary rocks need not generate large amounts of fluid themselves but could instead oxidize slab dehydration fluids ascending through them. Proposed Phanerozoic increases in arc magma oxygen fugacity may reflect the recycling of oxidative weathering products following Neoproterozoic–Palaeozoic marine and atmospheric oxygenation.
In-vitro pH-responsive release of imatinib from iron-supplement coated anatase TiO2 nanoparticles
Authors: Bhullar Shilpy , Goyal Navdeep , Gupta Shikha 
Published: March 2022

AbstractTargeted drug delivery is one such precision method of delivering medication inside the human body which can vanquish all the limitations of the conventional chemotherapeutic techniques. In the present study, two types of nanoparticles (NPs) were chosen for the in-vitro pH-responsive release study of the drug, Imatinib, namely anatase Titanium Dioxide nanoparticles (TiO2 NPs) and iron-capped TiO2 NPs, designated as Fe@TiO2 NPs. The novelty of this work lies behind the use of commercially available iron supplement ‘Autrin’ meant for human consumption, as the material to coat the TiO2 NPs to synthesize Fe@TiO2 NPs. The synthesized NPs were analyzed by XRD, HR‐TEM, SAED, EDX and VSM. UV–Vis spectroscopy was performed for absorption studies. Fe@TiO2 NPs showed superparamagnetic behavior and thus they are able to ensure the facile transfer of Imatinib via external magnetic fields. The results obtained from in-vitro drug release studies depicted that both TiO2 NPs and Fe@TiO2 NPs showed a controlled pH-sensitive delivery of the loaded Imatinib molecules. Moreover, both types of NPs do not result in the formation of ROS under human physiological conditions. These results can lay the foundation to the development of efficacious targeted drug delivery systems in the healthcare sector.
Species identification of silks by protein mass spectrometry reveals evidence of wild silk use in antiquity
Authors: Lee Boyoung , Pires Elisabete , Pollard A. Mark , McCullagh James S. O. 
Published: March 2022

AbstractSilk has been a luxurious commodity throughout modern human history and sericulture has played an important role in ancient global trade as well as technological and cultural developments. Archaeological findings suggest that prior to domestication of the mulberry silkworm (Bombyxmori) silks were obtained from a range of silk-producing moth species with regional specificity. However, investigating the origins of sericulture is difficult as classification of silks by species-type has proved technically challenging. We therefore investigated a range of methods for solubilising modern and archaeological silks and developed a mass spectrometry-based proteomics method that was able to successfully differentiate modern Bombyx,Antheraea, and Samia-produced silks down to the species level. We subsequently analysed archaeological silk materials excavated from the ancient city of Palmyra. Solubilisation behaviour and proteomic analysis provided evidence that the Palmyra silks were constructed from wild silk derived from Antheraeamylitta, the Indian Tasar silkworm. We believe this is the first species-level biochemical evidence that supports archaeological theories about the production and trade of Indian wild silks in antiquity.
Protective capacity of carotenoid trans-astaxanthin in rotenone-induced toxicity in Drosophila melanogaster
Authors: Akinade Temitope C. , Babatunde Oreoluwa O. , Adedara Adeola O. , Adeyemi Olugbenga E. , Otenaike Titilayomi A. , Ashaolu Onaara P. , Johnson Titilayo O. , Terriente-Felix Ana , Whitworth Alexander J. , Abolaji Amos O. 
Published: March 2022

AbstractTrans-astaxanthin (TA), a keto-carotenoid found in aquatic invertebrates, possesses anti-oxidative and anti-inflammatory activities. Rotenone is used to induce oxidative stress-mediated Parkinson’s disease (PD) in animals. We probed if TA would protect against rotenone-induced toxicity in Drosophila melanogaster. Trans-astaxanthin (0, 0.1, 0.5, 1.0, 2.5, 10, and 20 mg/10 g diet) and rotenone (0, 250 and 500 μM) were separately orally exposed to flies in the diet to evaluate longevity and survival rates, respectively. Consequently, we evaluated the ameliorative actions of TA (1.0 mg/10 g diet) on rotenone (500 μM)-induced toxicity in Drosophila after 7 days’ exposure. Additionally, we performed molecular docking of TA against selected pro-inflammatory protein targets. We observed that TA (0.5 and 1.0 mg/10 g diet) increased the lifespan of D. melanogaster by 36.36%. Moreover, TA (1.0 mg/10 g diet) ameliorated rotenone-mediated inhibition of Catalase, Glutathione-S-transferase and Acetylcholinesterase activities, and depletion of Total Thiols and Non-Protein Thiols contents. Trans-astaxanthin prevented behavioural dysfunction and accumulation of Hydrogen Peroxide, Malondialdehyde, Protein Carbonyls and Nitric Oxide in D. melanogaster (p < 0.05). Trans-astaxanthin showed higher docking scores against the pro-inflammatory protein targets evaluated than the standard inhibitors. Conclusively, the structural features of TA might have contributed to its protective actions against rotenone-induced toxicity.
Insights into countries’ exposure and vulnerability to food trade shocks from network-based simulations
Authors: Grassia Marco , Mangioni Giuseppe , Schiavo Stefano , Traverso Silvio 
Published: March 2022

AbstractIn the context of a global food system, the dynamics associated to international food trade have become key determinants of food security. In this paper, we resort to a diffusion model to simulate how shocks to domestic food production propagate through the international food trade network and study the relationship between trade openness and vulnerability. The results of our simulations suggest that low-income and food insecure countries tend to be the more exposed to external shocks and, at the same time, they are usually not in a position to take full advantage of international food trade when it comes to shield themselves from shocks to domestic production. We also study and discuss how nodes characteristics are associated with the propagation dynamics and with countries’ vulnerability, finding that simple centrality measures can significantly predict the magnitude of the shock experienced by individual countries.
Queueing theory model of pentose phosphate pathway
Authors: Kloska Sylwester M. , Pałczyński Krzysztof , Marciniak Tomasz , Talaśka Tomasz , Miller Marissa , Wysocki Beata J. , Davis Paul , Wysocki Tadeusz A. 
Published: March 2022

AbstractDue to its role in maintaining the proper functioning of the cell, the pentose phosphate pathway (PPP) is one of the most important metabolic pathways. It is responsible for regulating the concentration of simple sugars and provides precursors for the synthesis of amino acids and nucleotides. In addition, it plays a critical role in maintaining an adequate level of NADPH, which is necessary for the cell to fight oxidative stress. These reasons prompted the authors to develop a computational model, based on queueing theory, capable of simulating changes in PPP metabolites’ concentrations. The model has been validated with empirical data from tumor cells. The obtained results prove the stability and accuracy of the model. By applying queueing theory, this model can be further expanded to include successive metabolic pathways. The use of the model may accelerate research on new drugs, reduce drug costs, and reduce the reliance on laboratory animals necessary for this type of research on which new methods are tested.
Development of web-based dynamic nomogram to predict survival in patients with gastric cancer: a population-based study
Authors: Talebi Atefeh , Borumandnia Nasrin , Doosti Hassan , Abbasi Somayeh , Pourhoseingholi Mohamad Amin , Agah Shahram , Tabaeian Seidamir Pasha 
Published: March 2022

AbstractGastric cancer (GC) is the fifth most frequent malignancy worldwide and the third leading cause of cancer-associated mortality. The study’s goal was to construct a predictive model and nomograms to predict the survival of GC patients. This historical cohort study assessed 733 patients who underwent treatments for GC. The univariate and multivariable Cox proportional hazard (CPH) survival analyses were applied to identify the factors related to overall survival (OS). A dynamic nomogram was developed as a graphical representation of the CPH regression model. The internal validation of the nomogram was evaluated by Harrell’s concordance index (C-index) and time-dependent AUC. The results of the multivariable Cox model revealed that the age of patients, body mass index (BMI), grade of tumor, and depth of tumor elevate the mortality hazard of gastric cancer patients (P < 0.05). The built nomogram had a discriminatory performance, with a C-index of 0.64 (CI 0.61, 0.67). We constructed and validated an original predictive nomogram for OS in patients with GC. Furthermore, nomograms may help predict the individual risk of OS in patients treated for GC.