bluuebunny/crossref_metadata_2025_split huggingface dataset:
Designing green IoT communication by adaptive spotted hyena tunicate swarm optimization‐based cluster head selection
Authors: Das Anupam 
Published: July 2022

AbstractThe Internet of Things (IoT) has completely transformed the digital as well as virtual worlds of interconnected objects. In today's environment, the IoT describes a critical enabler for a broader variety of applications. Energy is at the center of the smart IoT application that allows the sensors to function. The sensors' ability to perform efficiently is hampered by rapid energy loss. To avoid the rapid loss of energy from sensors in the IoT, and energy‐effective method is necessary. Because heuristic approaches are not ideal for these issues and may turn into NP‐hard problems, meta‐heuristic techniques are mainly successful in solving various problems with near‐optimal solutions. This paper intends to develop a novel clustering protocol in Green IoT using a well‐performing novel hybrid adaptive meta‐heuristic algorithm. Here, an energy‐efficient clustering is performed by the hybrid spotted hyena optimization (SHO) and tunicate swarm algorithm (TSA) referred to as adaptive spotted hyena tunicate swarm optimization (ASHTSO) by deriving a multi‐objective function with “distance, energy, delay, security, and QoS”. The simulation findings show that the suggested technique outperforms existing algorithms significantly.
Clarifying the synergistic effects of emotion dysregulation and inhibitory control on physical aggression
Authors: Bounoua Nadia , Spielberg Jeffrey M. , Sadeh Naomi 
Published: July 2022

AbstractRising rates of violence underscore the need to better understand how systems that regulate distress and impulse control jointly modulate aggression risk. The goals of the current study were to investigate the unique and interactive effects of emotional dysregulation and inhibitory control on the perpetration of physical aggression. We recruited a high‐risk community sample of 206 adults (M/SDage = 33.55/10.89 years old; 47.1% female) who reported a range of physically aggressive behaviors. All participants completed a self‐report measure (Difficulties in Emotion Regulation Scale), neuropsychological testing (Color Word Interference Test), and clinical interviewing (Lifetime History of Aggression Interview), and a subset of individuals (n = 134) underwent a neuroanatomical scan. As expected, the interplay of emotional and inhibitory control explained unique variance in physical aggression above and beyond their main effects. The positive association between emotion dysregulation and aggression strengthened as inhibitory control decreased. Cortical thickness in two right prefrontal clusters, one that peaked in the superior frontal gyrus and one that peaked in the caudal middle frontal gyrus, was also associated with the interactive effects of emotional dysregulation and inhibitory control. Notably, thickness in the superior frontal gyrus mediated the association between emotion dysregulation and physical aggression at low levels of inhibitory control. Using a multilevel and multimethod approach, the present study revealed neuroanatomical correlates of emotion–cognition interactions that have translational relevance to violence perpetration. These findings extend previous work primarily focused on functional‐based neural assessments and point to the utility of examining neuroanatomical correlates of emotion–cognition interactions for understanding human aggression.
An analysis of the use of the relative source contribution term in derivation of drinking water standards using perfluorooctanoic acid as an example
Authors: Lindborg Analise , Bradley Ann , Durda Judi 
Published: July 2022

Abstract
The relative source contribution (RSC) term has long been used by the US Environmental Protection Agency (USEPA) and state regulatory agencies in setting criteria in water. The RSC reflects the proportion of the total daily intake of a chemical that can be derived from water when all other sources of exposure (e.g., food, air) are considered. This term is applied by the USEPA and state regulatory agencies when deriving ambient water quality criteria, maximum contaminant level goals, and drinking water health advisories for noncarcinogenic and threshold carcinogenic compounds. The value assigned to the RSC term affects the calculated criteria directly, with the allowable concentration in water decreasing with a decreasing RSC. A default RSC value of 20%—applied by regulatory entities in the USA for more than 40 years—assumes that 80% of an individual's exposure to a chemical's reference dose is from nonwater sources. Although the RSC is a chemical-specific parameter, there are few instances where a value other than the default of 20% has been approved and used. In 2000, USEPA outlined the process for developing chemical-specific RSC values, yet primary use of the default RSC value has continued since then. This article reviews USEPA's methodology for deriving chemical-specific RSC values and provides a case example using perfluorooctanoic acid (PFOA) to explore how the USEPA and state regulatory agencies are applying USEPA's guidance. The case study highlights inconsistent derivation of the RSC term, rooted in limitations in the current methodology. We suggest additional clarification of and more thoughtful use of the available data that may not meet USEPA's current adequacy requirements. We also recommend that the USEPA discuss recommendations for using biomonitoring data to set RSCs. Integr Environ Assess Manag 2023;19:605–612. © 2022 SETAC
Beneficial effect of polyphenols in COVID‐19 and the ectopic F1FO‐ATP synthase: Is there a link?
Authors: Panfoli Isabella , Esposito Alfonso 
Published: July 2022

AbstractCOVID‐19 has been proposed to be an endothelial disease, as endothelial damage and oxidative stress contribute to its systemic inflammatory and thrombotic events. Polyphenols, natural antioxidant compounds appear as promising agents to prevent and treat COVID‐19. Polyphenols bind and inhibit the F1Fo‐ATP synthase rotary catalysis. An early target of polyphenols may be the ectopic F1Fo‐ATP synthase expressed on the endothelial plasma membrane. Among the pleiotropic beneficial action of polyphenols in COVID‐19, modulation of the ecto‐F1Fo‐ATP synthase, lowering the oxidative stress produced by the electron transfer chain coupled to it, would not be negligible.
Research advances of N6‐methyladenosine in diagnosis and therapy of pancreatic cancer
Authors: Chen Sai , Ren Hefei , Zhang Xiaomin , Chang Liu , Wang Zhenhua , Wu Hongkun , Zhang Jiafeng , Ren Jigang , Zhou Lin 
Published: July 2022

AbstractBackgroundN6‐methyladenosine (m6A) is the addition of a methyl group on the N6 position of adenosine and is the most prevalent and abundant epigenetic modification in eukaryote mRNA. m6A marks are added to mRNA by the m6A methyltransferase complex (“writers”), removed by m6A demethylases (“erasers”), and recognized by m6A‐binding proteins (“readers”). Recent evidence has shown that the m6A modification plays a crucial role in the pathogenic mechanism and malignant progression of pancreatic cancer, with roles in cell survival, proliferation, migration, invasion, tumor metastasis, and drug resistance.MethodsLiterature was searched in Pubmed and Web of Science for the following keywords: “N6‐methyladenosine”, “pancreatic cancer”, “epigenetic modification”, “immunotherapy”.ResultsAmong classical m6A regulators, while METTL3, METTL14, WTAP, FTO, YTHDF2, IGF2BP1–3, hnRNPC, and NKAP are upregulated in pancreatic cancer, METTL16 and ALKBH5 are downregulated in pancreatic cancer. m6A modification has been investigated in pancreatic cancer therapy.ConclusionDysregulated m6A and its related factors in pancreatic cancer cells and patients indicate their potential values as novel biomarkers in pancreatic cancer diagnosis and targeted therapy.
IMPACT (Information Medically Pertinent in Acute Computed Tomography) requests: Delphi study to develop criteria standards for adequate clinical information in computed tomography requests in the Australian emergency department
Authors: Castillo Chelsea , Steffens Tom , Livesay Georgia , Sim Lawrence , Caffery Liam 
Published: July 2022

AbstractIntroductionInadequate clinical information in medical imaging requests negatively affects the clinical relevance of imaging performed and the quality of resultant radiology reports. Currently, there are no published Australian guidelines on what constitutes adequate clinical information in computed tomography (CT) requests. This study aimed to determine specific items of clinical information radiologists require in CT requests for acute chest, abdomen and blunt trauma examinations, to support optimal reporting.MethodsA panel of 24 CT‐reporting consultant radiologists participated in this e‐Delphi consensus study. Panellists undertook multiple online survey rounds of open‐ended, dichotomous and Likert scale questions, receiving feedback following each. Round 1 responses formulated lists for each CT examination. Round 2 set a threshold of 80% agreement after dichotomous scoring. Round 3 accepted items which averaged 4 or more on a 5‐point Likert scale. Round 4 required panellists to rank items within the aggregated, accepted lists, based on panellists' perceived level of usefulness.ResultsThe large numbers of round 1 items (chest: 101, abdomen: 76, blunt trauma: 80) were rationalised and grouped into categories to facilitate efficiency during subsequent rounds. Twenty‐three chest, 24 abdomen and 17 blunt trauma items met the 80% agreement threshold in round 2. Items below threshold were included in round 3; numbering 44, 19 and 23 for chest, abdomen and blunt trauma, respectively. Through the e‐Delphi process, we formulated clinical information criteria standards for three CT types.ConclusionsThe developed standards will guide Australian referrers in providing adequate clinical information in CT requests, to support optimal reporting, diagnosis and treatment.
Prevotella as the hub of the cervicovaginal microbiota affects the occurrence of persistent human papillomavirus infection and cervical lesions in women of childbearing age via host NF‐κB/C‐myc
Authors: Dong Binhua , Huang Yuxuan , Cai Hongning , Chen Yaojia , Li Ye , Zou Huachun , Lin Wenyu , Xue Huifeng , Feng Anping , Zhao Heping , Lu Yanfang , Gao Hangjing , Mao Xiaodan , Wu Zhihui , Pan Diling , Sun Pengming 
Published: July 2022

AbstractThere is evidence that coinfection of cervicovaginal high‐risk human papillomavirus (HR‐HPV) and bacteria is common in women of childbearing age. However, the relationship between bacterial vaginosis (BV) and persistent HR‐HPV infection in women of childbearing age and the underlying mechanisms remain unclear. In this study, we determined whether BV affects persistent HR‐HPV infection in women aged 20–45 years and explored the possible mechanisms of their interactions. From January 1 to April 30, 2020, we recruited women aged 20–45 years with and without BV at a ratio of 1:2 from Fujian Maternity and Child Health Hospital. All women were followed up at 0, 12, and 24 months. A BV assay, HR‐HPV genotyping and cervical cytology were performed at each follow‐up. At 0 months, additional vaginal secretions and cervical exfoliated cells were collected for 16S ribosomal RNA sequencing, bacterial metabolite determination, and POU5F1B, C‐myc, TLR4, NF‐κB, and hTERT quantification. A total of 920 women were included. The abundance of Prevotella (p = 0.016) and Gardnerella (p = 0.027) were higher, whereas the abundance of Lactobacillus was lower (p = 0.001) in women with persistent HR‐HPV infection and high‐grade squamous intraepithelial lesions (HSIL). The abundance of Prevotella (p = 0.025) and Gardnerella (p = 0.018) increased in the vaginas of women with persistent HPV16 infection, whereas only the abundance of Prevotella (p = 0.026) was increased in women with persistent HPV18 infection. The abundance of Prevotella in the vagina was significantly positively correlated with the expression levels of TLR4, NF‐κB, C‐myc, and hTERT in host cervical cells (p < 0.05). Our findings suggest that overgrowth of Prevotella in the vagina may influence the occurrence of persistent HR‐HPV infection‐related cervical lesions through host NF‐κB and C‐myc signaling.
Stochastic processes shape the aggregation of free‐living and particle‐attached bacterial communities in the Yangtze River Estuary, China
Authors: Shi Jing , Zuo Yaqiang , Qu Wu , Liu Xuezhu , Fan Yingping , Cao Pinglin , Wang Jianxin 
Published: July 2022

AbstractAn estuary plays an important role in material and energy exchange between the land and sea, where complex physical, chemical, and biological processes occur. Here, we investigated the assembly processes of free‐living (FL) and particle‐associated (PA) bacterial communities in two seawater layers at five stations in the Yangtze River Estuary (YRE) by using 16S rRNA sequencing methods. The results indicated that Proteobacteria was the most abundant phylum in the YRE. The α‐diversity of PA community was significantly higher than FL community, and analysis of similarity showed significantly different (Global R = 0.2809, p < 0.005). RDA revealed that phosphate (PO43−) was significantly correlated with PA bacterial community abundance (p < 0.05). An ecological null model showed that both PA and FL bacterial communities were mainly influenced by stochastic processes (PA: 100%, FL: 70%), which PA attached to nutrient particles and are less affected by environmental filtration. Dispersal limitation (50%) was the main assembly process of the PA community, while homogeneous selection (30%) and drift (30%) were important processes in the FL community assembly. The available substrate for colonization limits the transformation from FL to PA bacteria. This study would improve our understanding of FL and PA bacterial community structure and factors affecting assembly process in estuarine environments.
Supply chain transformation and technology management challenges in developing regions: Inductive theory building from rural Chinese nanostores
Authors: Guo Xitong , Lu Guanyi , Villena Veronica H. , Vogel Doug , Heim Gregory R. 
Published: July 2022

AbstractRural nanostores are the dominant source of packaged products for consumers in rural China, thus the more these stores order from reliable suppliers, the better the product quality available to rural areas. To improve merchandise circulation in rural areas, the Chinese government embarked on the large‐scale “Thousands of Villages” (ToV) program in 2005. One of its key components was the implementation of an information technology (IT) procurement system to facilitate transactions between rural nanostores and the ToV program's certified consumer packaged goods (CPG) suppliers. The nanostores' adoption of the ToV procurement system was encouraged yet voluntary. We study how this system was used initially and how it evolved over time. If effective, this program has the potential to address the growing social disparity between rural and developed areas in China. We first embarked on an exploratory analysis (March 2012) to understand the ToV program from the perspectives of nanostore owners, the ToV's CPG suppliers, and the government. We then collected interview data. In Period 1 (2013–2014), when the technology was still nascent, we found that nanostore owner's trust in the ToV's CPG suppliers, and system value, played key roles for nanostore owners to use the ToV procurement system. In Period 2 (2018–2019), three contextual factors emerged—population demographic shift, improved technology infrastructure, and trust in new [non‐ToV] purchasing platforms—each hindering the ToV procurement system's use. We observed strong government support during the early phases of ToV, but that support evolved from subsidizing the ToV platform and offering associated training (Period 1), to also providing credibility to competing non‐ToV procurement platforms (Period 2). Collectively, the findings identify idiosyncratic challenges that arise when public policies attempt to address developing region problems by reengineering supply chains via IT. We provide implications for IT research about technology management in rural developing areas and for managers to recognize potential pitfalls of managing IT projects in supply bases unfamiliar with advanced IT.
Paleoenvironmental dynamics in central‐eastern Brazil during the last 23 000 years: tropical peatland record in the Cerrado biome
Authors: Costa Camila Rodrigues , Pinto da Luz Cynthia Fernandes , Horák‐Terra Ingrid , de Camargo Plínio Barbosa , Barral Uidemar Morais , Mendonça‐Filho Carlos Victor , Gonçalves Thamyres Sabrina , Silva Alexandre Christófaro 
Published: July 2022

AbstractThe Cerrado biome is the second largest in Brazil, but the evolution of the Cerrado during the late Quaternary is not yet fully known. This study identifies paleoenvironmental changes during the last 23 000 years, based on a tropical mountain peatland record, in the Serra do Espinhaço Meridional in central‐eastern Brazil. A multi‐proxy approach was used that involved palynological analysis, stable isotopes (δ13C, δ15N), geochemistry, radiocarbon dating and multivariate statistics derived from a peatland core from Rio Preto (Minas Gerais state). The study reveals a very humid and cold climate during the late Pleistocene, with an increase in temperature and decrease in humidity at the Pleistocene–Holocene transition. During this period there was strong instability in the landscape (episodes of erosion). At the beginning of the Holocene there was a reduction in humidity with greater landscape stability. The current sub‐humid climatic conditions seem to have been established in the mid‐/late Holocene, with periods of landscape instability. Our findings agree with other Cerrado records that contradict previously established hypotheses, such as the Amazonian Refuge and the Pleistocene Arc.
In vitro germination and controlled release fertilizer effects on ex vitro development of Eugenia uniflora L. plantlets
Authors: Simão Mariela Justiniano , Cola Marília Poton Arcobeli , da Silva Nina Claudia Barboza 
Published: July 2022

AbstractBackgroundEugenia uniflora L (Myrtaceae) is a native shrub from Brazil and is used in traditional medicine and also in the food industry to produce different types of juices, jellies, ice cream, and can also be consumed unprocessed. This species is propagated by seeds, which have irregular germination leading to low producer orchards affecting its economic viability for large‐scale production and the quality of seedlings. Thus, the main goal of this study was to evaluate different in vitro germination conditions and the effects of substrate and fertilizer on ex vitro plantlets development.ResultsSeeds germinated in MS0 under light had the highest speed germination index (1.63). The highest root system length was observed in seeds cultivated in MS + 1 μmol GA3 in the presence of light (12.85 cm). Plantlets developed under MS + 1 μmol GA3 in the presence of light, showed the highest dry weight mass (29.7 mg). The three‐way ANOVA indicated that the type of fertilizer, culture medium, and light conditions separately showed significant effects on shoot length (p < 0.0001, 0.0278, and 0.036 respectively), root collar diameter (p < 0.0001, 0.0428, and 0.0165, respectively) and also for the fresh and dry weight of the shoot, just by the type of fertilizer (p < 0.0001) and culture medium (p < 0.05) used.ConclusionIt was concluded that MS0 under light is the most suitable condition for Brazilian cherry germination and commercial substrate plus the controlled release NPK 15‐9‐12 fertilizer provides better plant growth.
A case of contact stomatitis of the oral floor caused by magnesium oxide in an elderly with paralysis
Authors: Okubo Masahiko , Kamimura Hideyuki , Fukushima Yosuke , Ito Ko , Sato Tsuyoshi , Kokabu Shoichiro 
Published: July 2022

AbstractBackgroundOn the mucosa, the retention of drugs including magnesium oxide for laxative sometimes causes drug‐induced contact mucositis.Case presentationA 72‐year‐old man presented with discomfort in the oral floor. He suffered from paralysis on the right side of his body. After his meal, it was observed magnesium oxide were retained on the right side of the oral floor. After our instruction of taking drugs with food thickening agents, his mucosa became normal soon.ConclusionWe realized that the supervising of taking medicine in the right way is important for the patients such as oral dysphagia especially with elderly and paralysis.
Water transport in epoxy/polyurethane interpenetrating networks
Authors: Bratasyuk Nikita A. , Ostanin Stepan A. , Mokeev Maxim V. , Zuev Vjacheslav V. 
Published: July 2022

AbstractDiffusion of water in epoxy–polyurethane (PU) interpenetrating networks was investigated using gravimetry, time‐resolved ATR‐FTIR, and 2D correlation analysis. In this study, the amount of PU component and the length of polyethylene oxide soft block in them were systematically varied to determine their influence on water uptake. The diffusion coefficients were calculated and anomalous water diffusion is well described by the Carter and Kibler model. Water molecules of four different states were identified in the network volume, and sequence of their formation was determined by 2D‐IR spectroscopy. One of them could be confined into free volume (microvoids) or molecularly dispersed with hydrogen‐bonding at cluster formation (bulk dissolved), while the others could be attributed to the bound water forming strong hydrogen bonds with hydrophilic entities of networks. These results were supported by solid‐state 2H NMR data. The influence of water uptake on thermomechanical behavior of epoxy/PU networks was determined. It was shown that the increase of PU content in composites leads to the changes of the effect of water uptake from plasticizing to the anti‐plasticizing as a result of the formation of new networks of interchain hydrogen bonds.
A review on the alternative of indium tin oxide coated glass substrate in flexible and bendable organic optoelectronic device
Authors: Shankar Uday , Oberoi Deepa , Bandyopadhyay Anasuya 
Published: July 2022

AbstractFlexible and optically transparent electrodes (TEs) are essential for most state‐of‐art organic optoelectronic devices (OOED). The demand for bendable electronic devices with aesthetic impact and multi‐functionality has driven the rapid development of flexible TEs with improved optoelectrical and mechanical properties. However, conventional rigid TEs, that is, indium tin oxide (ITO) coated glass substrate (ITO/glass), cannot match smart devices' requirements in unique fields, like electrochromic devices, electronic skins, and wearable electronics, foldable displays, smart windows, and solar cells. To substitute extensively used ITO/glass electrodes has been endeavored because of the increasing price and inherently brittle ITO and glass substrate behavior. Emerging TEs based on the combination of the polymers substrate and conducting fillers like graphene, carbon nanotubes, metal nanowires, and transparent conducting oxides are bendable, lightweight, and inexpensive. They have shown substantial prospects to be used in the devices mentioned above. With each tiny development in these emerging TE‘s, such as outstanding optoelectrical and mechanical features in flexible electrodes, they become more suitable for practical applications in miscellaneous bendable devices. This review summarizes the comprehensive overview of the modern alternative flexible TEs and their implementation in bendable and stretchable devices.