bluuebunny/crossref_metadata_2025_split huggingface dataset:
Challenging gender norms: women’s leadership, political authority, and autonomy
Authors: Lari Noora , Al-Ansari Mohammad , El-Maghraby Engi 
Published: January 2022

Purpose
In patriarchal settings, cultural barriers continue to influence women’s participation in positions of leadership and political authority. This paper aims to explore these findings in light of the theoretical concepts of “hegemonic masculinity” and “patriarchy,” which explain gender disparities in the occupancy of political power and leadership positions in Qatar.

Design/methodology/approach
Data from original face-to-face national surveys conducted among subjects in Qatar were used, including 1,611 completed household interviews.

Findings
The findings were consistent with the prevailing patriarchal beliefs present in Qatari society and Arab Gulf States. The analysis showed that there was greater significant support for men holding key leadership and authority positions than women. Individual-level factors were found to have a significant association with attitudes favoring women. Compared to respondents who had never attended school, those who had completed secondary school and those who had partaken in higher education favored having women in leadership roles.

Practical implications
As a means to fix the gender imbalance within the occupancy of positions of political power in Qatar, this study recommends putting substantial efforts into increasing the number of interventions underpinning gender equality through social awareness programs that may improve the public’s perceptions. Furthermore, gender-equitable affirmative actions are needed to promote the inclusion of women in power and increase their presence in leadership roles.

Originality/value
This study is among the very few that have theoretically and empirically addressed the issue of women’s authority and involvement in key leadership roles in the context of Qatar.
Information and communication technologies in food services and restaurants: a systematic review
Authors: Gonzalez Reyes , Gasco Jose , Llopis Juan 
Published: January 2022

Purpose
Information and communication technologies (ICTs) are a key player in the food services and restaurants sector; thus, the aim of this work consists in studying the previous research on ICTs in food services and restaurants in the context of tourism and hospitality through a systematic literature review.

Design/methodology/approach
The systematic literature review is performed on full papers published in journals included in the Journal Citation Report of the WoS in the category of Hospitality, Leisure, Sport and Tourism. A total of 165 articles from 28 journals are analyzed, following different criteria, such as the research methods, perspectives, statistical techniques, geographical focus, topics, technologies, authors and universities.

Findings
The restaurant sector is more and more based on the creation of experiences and ICTs, through their multiple possibilities, can undoubtedly contribute to adding value to the simple meal and create and recreate experiences to attract and retain customers who are increasingly sophisticated and hooked on ICTs. ICTs are basic for managers taking decision at the highest level in food services and restaurants, so ICTs should not be seen as a technical tool but as an essential element for top management.

Research limitations/implications
This paper examined articles from very well-known tourism and hospitality journals, leaving aside others as well as different publication formats such as books or papers presented at conferences.

Originality/value
A significant contribution made with this paper is the availability of a list of topics in the context of ICTs in food services and restaurants. These topics are classified into three areas (Consumers, Suppliers and Environment and Tendencies) that can serve as a future research framework. The paper also provides useful information to restaurant managers about ICTs, to researchers for their future projects and to academics for their courses.
Determinants of Muslim consumers’ halal cosmetics repurchase intention: an emerging market’s perspective
Authors: Shahid Shadma , Parray Mohammad Ashraf , Thomas George , Farooqi Rahela , Islam Jamid Ul 
Published: January 2022

Purpose
Due to a staggering growth rate in the recent past, halal products have attained a significant attention of marketers across countries. However, marketing practitioners seek to have detailed understanding of what drives consumers of different demographics towards this product category so as to better market and position themselves in the competitive landscape. Correspondingly, this study aims to provide insights into the Muslim women consumers’ halal cosmetics purchase behaviour and examines the variables (and their interplay) when purchasing such products.

Design/methodology/approach
The data for the study were collected through a self-administered questionnaire from 371 Muslim respondents from India. The data were analysed through structural equation modelling using AMOS 22.0 SEM software.

Findings
The findings of this study reveal that religious knowledge, religious commitment and halal certification(s) affect consumers’ actual purchase behaviour of halal cosmetics, which subsequently drives their repurchase intention. The findings further reveal a non-significant effect of religious orientation with both the actual purchase behaviour and repurchase intention towards halal cosmetics. Additionally, actual purchase behaviour of halal cosmetics is found to positively affect customers’ repurchase intentions.

Originality/value
Despite the recent growth of overall beauty industry, this particular segment of halal cosmetics has a huge potential given the phenomenal preference that Muslim consumers have shown in such niche. Therefore, this paper contributes towards examining the key factors influencing consumers purchase behaviour towards halal cosmetics in India that can be capitalized on.
Does psychological safety at school affect psychological capital at work? Evidence from part-time MBA students
Authors: Wu Fan , Chen Guoquan , Xiang Shuting 
Published: January 2022

PurposeExisting research regarding the value of school education focuses primarily on the effects of educational level on core task performance after graduation. However, it is worth noting that knowledge, skills and abilities are not the only individual gains from school education. For part-time Master of Business Administration (MBA) students, the impact of MBA education on their real-time work during their two-year or so study journey has not been reported. This study aims to provide theoretical reasoning and empirical insights to clarify the impact of psychological safety at school on psychological capital (PsyCap) at work for part-time MBA students and examines the moderating role of constructive controversy at school in this relationship.Design/methodology/approachA survey of 286 part-time MBA students was conducted in a university located in Beijing to address the theoretical issue.FindingsStudents’ psychological safety at school is positively related to PsyCap at work. Constructive controversy at school acts as a positive moderator in the relationship between psychological safety at school and PsyCap at work.Originality/valueThis study establishes a link between the school and the workplace. It explores the relationship between an individual’s psychological states at school and at work and contributes to the literature on human resources and management education. Furthermore, the findings prove that students not only gain knowledge, skills and abilities from education but also positive psychological states, such as psychological safety.
Antimicrobial effects of chitosan and garlic against Salmonella spp., Escherichia coli O157:H7, and Listeria monocytogenes in hummus during storage at various temperatures
Authors: Osaili Tareq M. , Al‐Nabulsi Anas A. , Hasan Fayeza , Olaimat Amin N. , Taha Sadi , Ayyash Mutamed , Nazzal Dima S. , Savvaidis Ioannis N. , Obaid Reyad S. , Holley Richard 
Published: January 2022

AbstractThe study aimed to evaluate the antimicrobial activity of 0.5 or 1% (w/w) chitosan and 1% (w/w) garlic against Salmonella spp., Escherichia coli O157:H7 and Listeria monocytogenes in hummus dip stored at 4, 10, or 25°C for 28, 21, or 7 days, respectively. In hummus without garlic, at all storage temperatures and storage periods, 0.5% chitosan decreased Salmonella spp., E. coli O157:H7, and L. monocytogenes by 0.9–2.3, 0.6–2.3, and 0.9–1.3 log CFU/g, respectively. In comparison, 1% chitosan decreased the numbers by 1.6–2.9, 1.4–2.7, and 1.3–1.8 log CFU/g, respectively. In hummus with 1% garlic, 0.5% chitosan decreased Salmonella spp., E. coli O157:H7, and L. monocytogenes by 0.7–2.5, 0.6–2.2, and 1.0–1.5 log CFU/g, respectively. Furthermore, 1% chitosan decreased the numbers by 1.6–2.8, 1.2–2.7, and 1.5–1.6 log CFU/g, respectively. With few exceptions, adding 1% garlic to hummus did not result in any significant reduction (at p < 0.05) in microbial numbers. The greatest decreases of Salmonella spp., E. coli O157:H7, and L. monocytogenes were 3.1, 3.6, and 2.9 log CFU/g with 1% chitosan held at 4°C for 28 days. The highest overall acceptability was for hummus with 0.5% chitosan + 1% garlic. Commercial use of chitosan is expected to help producers improve hummus safety.Practical ApplicationHummus is consumed worldwide as a dip due to its taste and health benefits. Microbial safety of hummus can be enhanced by incorporating chitosan, derived from the natural polymer chitin, into the formulation. This enhanced recipe would be a bonus for producers and consumers alike.
Kombucha: A review of substrates, regulations, composition, and biological properties
Authors: de Miranda Jeniffer Ferreira , Ruiz Larissa Fernandes , Silva Cíntia Borges , Uekane Thais Matsue , Silva Kelly Alencar , Gonzalez Alice Gonçalves Martins , Fernandes Fabrício Freitas , Lima Adriene Ribeiro 
Published: January 2022

AbstractKombucha has been gaining prominence around the world and becoming popular due to its good health benefits. This beverage is historically obtained by the tea fermentation of Camellia sinensis and by a biofilm of cellulose containing the symbiotic culture of bacteria and yeast (SCOBY). The other substrates added to the C. sinensis tea have also been reported to help kombucha production. The type as well as the amount of sugar substrate, which is the origin of SCOBY, in addition to time and temperature of fermentation influence the content of organic acids, vitamins, total phenolics, and alcoholic content of kombucha. The route involved in the metabolite biotransformation identified in kombucha so far and the microorganisms involved in the process need to be further studied. Some nutritional properties and benefits related to the beverage have already been reported. Antioxidant and antimicrobial activities and antidiabetic and anticarcinogenic effects are some of the beneficial effects attributed to kombucha. Nevertheless, scientific literature needs clinical studies to evaluate these benefits in human beings. The toxic effects associated with the consumption of kombucha are still unclear, but due to the possibility of adverse reactions occurring, its consumption is contraindicated in infants and pregnant women, children under 4‐years‐old, patients with kidney failure, and patients with HIV. The regulations in place for kombucha address a number of criteria, mainly for the pH and alcohol content, in order to guarantee the quality and safety of the beverage as well as to ensure transparency of information for consumers.
Contingent stimulus delivery assay for zebrafish reveals a role for CCSER1 in alcohol preference
Authors: Nathan Fatima Megala , Kibat Caroline , Goel Tanisha , Stewart James , Claridge‐Chang Adam , Mathuru Ajay S. 
Published: January 2022

AbstractAlcohol use disorders are complex, multifactorial phenomena with a large footprint within the global burden of diseases. Here, we report the development of an accessible, two‐choice self‐administration zebrafish assay (SAZA) to study the neurobiology of addiction. Using this assay, we first demonstrated that, although zebrafish avoid higher concentrations of alcohol, they are attracted to low concentrations. Pre‐exposure to alcohol did not change this relative preference, but acute exposure to an alcohol deterrent approved for human use decreased alcohol self‐administration. A pigment mutant used in whole‐brain imaging studies displayed a similar relative alcohol preference profile; however, mutants in CCSER1, a gene associated with alcohol dependence in human genetic studies, showed a reversal in relative preference. The presence of a biphasic response (hormesis) in zebrafish validated a key aspect of vertebrate responses to alcohol. SAZA adds a new dimension for discovering novel alcohol deterrents and studying the neurogenetics of addiction using the zebrafish.
Competing Principals? Legislative Representation in List Proportional Representation Systems
Authors: Buisseret Peter , Prato Carlo 
Published: January 2022

AbstractWe develop a new framework to study legislative representation in list proportional representation (PR) systems. Our model studies a legislator's incentives to balance the competing interests of party leaders and local voters under a variety of list PR systems. We consider open and closed lists, as well as flexible lists—in which both rank assignments and preference votes determine the order in which seats are filled. We find that more flexibility can worsen local representation. List flexibility also acts as a key mediator of the effect of voter partisanship on party cohesion. And, our analysis reveals that higher district magnitude encourages representatives to toe the party line under all ballot systems.
Resolution of iron deficiency following successful eradication of Helicobacter pylori in children
Authors: Tanous Osama , Levin Carina , Suchdev Parminder S. , Luo Hanqi , Rinawi Firas 
Published: January 2022

AbstractAimTo assess correlation between successful Helicobacter pylori (HP) eradication and resolution of iron deficiency in children, without iron supplementation.MethodsMedical records of children diagnosed with HP infection based on endoscopy were retrospectively reviewed. Among those with non‐anaemic iron deficiency (NAID) or iron deficiency anaemia (IDA), haemoglobin, ferritin and CRP levels were compared prior and 6–9 months’ post‐successful HP eradication. Predictors of resolution of iron deficiency following HP eradication were assessed.ResultsAmong 60 included children (median age 14.8, IQR12.3–16 years; 62% males), 35% had IDA while the remaining 65% had NAID. Following successful HP eradication, iron normalised in 60% of patients with iron deficiency (ID), without iron supplementation. There were significant improvements in haemoglobin and ferritin concentrations following HP eradication with haemoglobin increasing from 12.3 g/dL to 13.0 g/dL and ferritin increasing from 6.3 μg/L to 15.1 μg/L (p < 0.001). In multiple logistic regression, older age was the only factor associated with resolution of anaemia following HP eradication (OR 1.65, 95% CI 1.16–2.35, p = 0.005).ConclusionSuccessful HP eradication could be helpful in improving iron status among children with refractory NAID or IDA. Older age may predict this outcome. Screening for HP might be considered in the workup of refractory IDA or ID.
Effect of inclusion levels of low‐fat dried distillers grains in finishing diets on protein and energy intake and retention and estimation of protein and energy requirements of young Nellore bulls fed with high concentrate diets
Authors: Alhadas Herlon M. , Valadares Filho Sebastião C. , Tedeschi Luis O. , Vilela Rizielly S. R. , Souza Gilyard A. P. , Lage Bruno C. , Silva Breno C. , Rennó Luciana N. , Paulino Mario F. 
Published: January 2022

AbstractThe objective was to evaluate the effect of including low‐fat dried distillers grains (DDG) in finishing diets on protein and energy intake and retention and to estimate the protein and energy requirement of young Nellore bulls. Thirty‐five animals were used: baseline (n = 4), maintenance (n = 4), and ad libitum intake (n = 27). Ad libitum animals were divided into four groups: diets with the inclusion of DDG at the levels of 0, 150, 300, and 450 g/kg (dry matter basis). At the end of the experiment, all animals were slaughtered. There was a linear reduction with increasing DDG levels in the total digestible nutrients intake (p = 0.008), metabolizable energy (ME) intake (p < 0.010), in total retained energy (p = 0.065), and in heat production (p < 0.001). Metabolizable protein (MP) intake increased linearly (p < 0.010) but retained protein did not differ (p = 0.499). Daily net energy and ME requirement for maintenance were 75.9 and 122 kcal/kg0.75 EBW, respectively. Daily MP for maintenance was 3.6 g/kg0.75 shrunk body weight. DDG inclusion in finishing diets reduces energy intake and deposition, and we recommend the equations of this study to estimate the requirements of young Nellore bulls.
Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double‐blind, placebo‐controlled, cross‐over study
Authors: Ruijs Titia Q. , Heuberger Jules A. A. C. , de Goede Annika A. , Ziagkos Dimitrios , Otto Marije E. , Doll Robert J. , van Putten Michel J. A. M. , Groeneveld Geert Jan 
Published: January 2022

AimsThe purpose of this study was to investigate pharmacodynamic effects of drugs targeting cortical excitability using transcranial magnetic stimulation (TMS) combined with electromyography (EMG) and electroencephalography (EEG) in healthy subjects, to further develop TMS outcomes as biomarkers for proof‐of‐mechanism in early‐phase clinical drug development. Antiepileptic drugs presumably modulate cortical excitability. Therefore, we studied effects of levetiracetam, valproic acid and lorazepam on cortical excitability in a double‐blind, placebo‐controlled, 4‐way cross‐over study.MethodsIn 16 healthy male subjects, single‐ and paired‐pulse TMS‐EMG–EEG measurements were performed predose and 1.5, 7 and 24 hours postdose. Treatment effects on motor‐evoked potential, short and long intracortical inhibition and TMS‐evoked potential amplitudes, were analysed using a mixed model ANCOVA and cluster‐based permutation analysis.ResultsWe show that motor‐evoked potential amplitudes decreased after administration of levetiracetam (estimated difference [ED] −378.4 μV; 95%CI: −644.3, −112.5 μV; P < .01), valproic acid (ED −268.8 μV; 95%CI: −532.9, −4.6 μV; P = .047) and lorazepam (ED −330.7 μV; 95%CI: −595.6, −65.8 μV; P = .02) when compared with placebo. Long intracortical inhibition was enhanced by levetiracetam (ED −60.3%; 95%CI: −87.1%, −33.5%; P < .001) and lorazepam (ED −68.2%; 95%CI: −94.7%, −41.7%; P < .001) at a 50‐ms interstimulus interval. Levetiracetam increased TMS‐evoked potential component N45 (P = .004) in a central cluster and decreased N100 (P < .001) in a contralateral cluster.ConclusionThis study shows that levetiracetam, valproic acid and lorazepam decrease cortical excitability, which can be detected using TMS‐EMG–EEG in healthy subjects. These findings provide support for the use of TMS excitability measures as biomarkers to demonstrate pharmacodynamic effects of drugs that influence cortical excitability.
The anti‐C5a antibody vilobelimab efficiently inhibits C5a in patients with severe COVID‐19
Authors: Vlaar Alexander P. J. , Lim Endry H. T. , de Bruin Sanne , Rückinger Simon , Pilz Korinna , Brouwer Matthijs C. , Guo Ren‐Feng , Heunks Leo M. A. , Busch Matthias H. , van Paassen Pieter , Riedemann Niels C. , van de Beek Diederik 
Published: January 2022

AbstractRecently, we reported the phase II portion of the adaptive phase II/III PANAMO trial exploring potential benefit and safety of selectively blocking C5a with the monoclonal antibody vilobelimab (IFX‐1) in patients with severe coronavirus disease 2019 (COVID‐19). The potent anaphylatoxin C5a attracts neutrophils and monocytes to the infection site, causes tissue damage by oxidative radical formation and enzyme releases, and leads to activation of the coagulation system. Results demonstrated that C5a inhibition with vilobelimab was safe and secondary outcomes appeared in favor of vilobelimab. We now report the pharmacokinetic/pharmacodynamic (PK/PD) analysis of the phase II study. Between March 31 and April 24, 2020, 30 patients with severe COVID‐19 pneumonia confirmed by real‐time polymerase chain reaction were randomly assigned 1:1 to receive vilobelimab plus best supportive care or best supportive care only. Samples for measurement of vilobelimab, C3a and C5a blood concentrations were taken. Vilobelimab predose (trough) drug concentrations in plasma ranged from 84,846 to 248,592 ng/ml (571 to 1674 nM) with a geometric mean of 151,702 ng/ml (1022 nM) on day 2 and from 80,060 to 200,746 ng/ml (539 to 1352 nM) with a geometric mean of 139,503 ng/ml (939 nM) on day 8. After the first vilobelimab infusion, C5a concentrations were suppressed in the vilobelimab group (median 39.70 ng/ml 4.8 nM, IQR 33.20–45.55) as compared to the control group (median 158.53 ng/ml 19.1 nM, IQR 60.03–200.89, p = 0.0006). The suppression was maintained on day 8 (p = 0.001). The current PK/PD analysis shows that vilobelimab efficiently inhibits C5a in patients with severe COVID‐19.
Impaired awareness of hypoglycaemia in women with type 1 diabetes in pregnancy: Hypoglycaemia fear, glycaemic and pregnancy outcomes
Authors: Bahrami Jasmine , Tomlinson George , Murphy Helen R. , Feig Denice S. ,   the CONCEPTT Collaborative Group
Published: January 2022

AbstractAimsTo examine maternal fear of hypoglycaemia, glycaemia and pregnancy outcomes in women with impaired and normal awareness of hypoglycaemia.MethodsA pre‐planned sub‐study of 214 pregnant women with type 1 diabetes who participated in the CONCEPTT trial. Participants completed hypoglycaemia fear surveys (HFS‐II) at baseline. Logistic regression and Poisson regression analyses were used to obtain an adjusted estimate for the rate ratio relating awareness to the number of severe hypoglycaemic episodes, and for several neonatal outcomes in relation to the total HFS‐II score. The role of continuous glucose monitoring (CGM) use was examined.ResultsOverall, 30% of participants reported impaired awareness of hypoglycaemia (n = 64). Women with impaired awareness of hypoglycaemia had more episodes of severe hypoglycaemia (mean 0.44 vs. 0.08, p < 0.001) (12–34 weeks gestation) and scored higher on the HFS‐II scale (43.7 vs. 36.0, p 0.008), indicating more fear of hypoglycaemia. They spent more time below range (CGM <3.5 mmol/L) and exhibited more glycaemic variability at 12 weeks gestation. Higher overall HFS‐II scores were associated with a higher risk of maternal severe hypoglycaemia episodes (Rate Ratio 1.78, 95% CI 1.39–2.27). Women with impaired awareness of hypoglycaemia had less maternal weight gain but there were no differences in neonatal outcomes between women with impaired awareness of hypoglycaemia and normal hypoglycaemia awareness. Higher HFS‐II scores were associated with more nephropathy (Odds Ratio 1.91, 95% CI 1.06–3.4). CGM use after 12 weeks was not associated with the number of episodes of severe hypoglycaemia (RR 0.75, 95% CI 0.49–1.15; p = 0.18).ConclusionsIn pregnant women with type 1 diabetes, impaired awareness of hypoglycaemia is associated with more maternal severe hypoglycaemia episodes and more fear of hypoglycaemia. Having impaired awareness of hypoglycaemia and/or fear of hypoglycaemia should alert clinicians to this increased risk. Reassuringly, there was no increase in adverse neonatal outcomes.