bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hear me, see me, trust you – job burnout and disengagement of Australian aged care workers
Authors: Olley Richard 
Published: September 2022

Purpose
The themes that emerged from the qualitative data of a mixed methods study that explored the effects of leadership style on the job satisfaction of aged care workers.

Design/methodology/approach
The study is a mixed methods study with the qualitative approach informing the interpretative phenomenological analysis from the transcripts of semi-structured interviews.

Findings
Three themes related to the effects of leadership style on job satisfaction of aged care employees emerged from the IPA. These themes were, The Context of Aged Care, Employee Engagement and Voice and Leader Behaviour. Job burnout and organisational disengagement were prevalent in participants of the qualitative study.

Research limitations/implications
The research deployed quantitative measurements to determine the differences between aged care leaders and their followers and used these to explore participants’ lived experiences and how they made sense of their personal and social worlds at work. In the quantitative study, there may be an overstatement of the strength of the relationship between variables among those motivated to participate in the study. The qualitative study requires the researcher to be thorough in describing the research context, and it may be that those who wish to transfer the results of this study to a different one are responsible for making the judgement on the suitability of the transferability of findings.

Practical implications
Decreasing job disengagement and burnout will positively impact reducing attrition and turnover and, thus, the availability of the aged care workforce. It will inform leadership development programs and training in aged care and other health and social care sectors.

Social implications
The workforce is a primary consideration for aged care in Australia and globally. Reducing burnout and disengagement will reduce workforce attrition, thus, improving the care for some of the most vulnerable in the population.

Originality/value
This report is from original research with ethical clearance from a university human research ethics committee contributing to the knowledge of leadership practice in aged care in Australia.
Exploring dialogic analysis and thematic analysis of place conversations with older adults
Authors: Weil Joyce 
Published: September 2022

Purpose
Although thematic analysis is a commonly used technique, this paper aims to explore the potential advantages (and drawbacks) of both thematic analysis and a dialogic approach to qualitative data analysis.

Design/methodology/approach
Initially, the epistemology and application of each design, thematic analysis and dialogic analysis are compared. Then, examples of coding segments of narrative data from 85 open-ended interviews with older adults exploring the meaning of place and place-attachment are presented through both thematic and dialogic analyses.

Findings
The conclusion offers suggestions about how dialogic analysis can add additional context and more participant inclusion and agency to thematic analysis.

Originality/value
The blending of these two qualitative analysis approaches offers better emphasis on fully presenting older individuals’ narratives.
The influence of H2 partial pressure on biogenic palladium nanoparticle production assessed by single‐cell ICP‐mass spectrometry
Authors: Law Cindy Ka Y. , Bolea‐Fernandez Eduardo , Liu Tong , Bonin Luiza , Wallaert Elien , Verbeken Kim , De Gusseme Bart , Vanhaecke Frank , Boon Nico 
Published: September 2022

AbstractThe production of biogenic palladium nanoparticles (bio‐Pd NPs) is widely studied due to their high catalytic activity, which depends on the size of nanoparticles (NPs). Smaller NPs (here defined as <100 nm) are more efficient due to their higher surface/volume ratio. In this work, inductively coupled plasma‐mass spectrometry (ICP‐MS), flow cytometry (FCM) and transmission electron microscopy (TEM) were combined to obtain insight into the formation of these bio‐Pd NPs. The precipitation of bio‐Pd NPs was evaluated on a cell‐per‐cell basis using single‐cell ICP‐MS (SC‐ICP‐MS) combined with TEM images to assess how homogenously the particles were distributed over the cells. The results provided by SC‐ICP‐MS were consistent with those provided by “bulk” ICP‐MS analysis and FCM. It was observed that heterogeneity in the distribution of palladium over an entire cell population is strongly dependent on the Pd2+ concentration, biomass and partial H2 pressure. The latter three parameters affected the particle size, ranging from 15.6 to 560 nm, and exerted a significant impact on the production of the bio‐Pd NPs. The TEM combined with SC‐ICP‐MS revealed that the mass distribution for bacteria with high Pd content (144 fg Pd cell−1) indicated the presence of a large number of very small NPs (D50 = 15.6 nm). These results were obtained at high cell density (1 × 105 ± 3 × 104 cells μl−1) and H2 partial pressure (180 ml H2). In contrast, very large particles (D50 = 560 nm) were observed at low cell density (3 × 104 ± 10 × 102 cells μl−1) and H2 partial pressure (10–100 ml H2). The influence of the H2 partial pressure on the nanoparticle size and the possibility of size‐tuned nanoparticles are presented.
Evaluation of Select Velocity Measurement Techniques for Estimating Discharge in Small Streams across the United States
Authors: King Tyler , Hundt Stephen , Simonson Amy , Blasch Kyle 
Published: September 2022

ABSTRACTMultiple instruments and methods exist for collecting discrete streamflow measurements in small streams with low flows, defined here as less than 5.7 m3/s (200 ft3/s). Included in the available methods are low‐cost approaches that are infrequently used, in part, because their uncertainty is not well known. In this work, we evaluated the accuracy and suitability of three low‐cost velocity measurement methods (surface float [SF], velocity head rod [VR], and rising body [RB]) and three conventional current meters (acoustic Doppler velocimeter, and mechanical Price type AA and Price Pygmy meters) relative to discharge calculated from stable artificial hydraulic controls. A total of 231 measurements were made by 20 individuals during 88 site visits to 24 sites in eight states. Accuracies were assessed for all methods and precision was evaluated for the low‐cost methods. The median percent error was below 5% for conventional methods, and below 20% for the low‐cost methods. The SF was the most accurate (median absolute percent error 14%) and precise (mean percent precision of 11%) low‐cost method. The RB and VR, respectively, had 15% and 20% median absolute percent error and 29% and 12% mean percent precision. Results suggest that low‐cost methods, when used appropriately, can be used to estimate discharge data under low flow conditions when measurements with conventional methods are not feasible and the associated accuracies meet end‐user measurement objectives.
Disparities in emergency department prioritization and rooming of patients with similar triage acuity score
Authors: Lin Peter , Argon Nilay T. , Cheng Qian , Evans Christopher S. , Linthicum Benjamin , Liu Yufeng , Mehrotra Abhishek , Patel Mehul D. , Ziya Serhan 
Published: September 2022

AbstractBackgroundWe identify patient demographic and emergency department (ED) characteristics associated with rooming prioritization decisions among ED patients who are assigned the same triage acuity score.MethodsWe performed a retrospective analysis of adult ED patients with similar triage acuity, as defined as an Emergency Severity Index (ESI) of 3, at a large academic medical center, during 2019. Violations of a first‐come‐first‐served (FCFS) policy for rooming are identified and used to create weighted multiple logistic regression models and 1:M matched case–control conditional logistic regression models to determine how rooming prioritization is affected by individual patient age, sex, race, and ethnicity after adjusting for patient clinical and time‐varying ED operational characteristics.ResultsA total of 15,781 ED encounters were analyzed, with 1612 (10.2%) ED encounters having a rooming prioritization in violation of a FCFS policy. Patient age and race were found to be significantly associated with being prioritized in violation of FCFS in both logistic regression models. The 1:M matched model showed a statistically significant relationship between violation of rooming prioritization with increasing age in years (adjusted odds ratio [aOR] 1.009, 95% confidence interval [CI] 1.005–1.013) and among African American patients compared to Caucasians (aOR 0.636, 95% CI 0.545–0.743).ConclusionsAmong ED patients with a similar triage acuity (ESI 3), we identified patient age and patient race as characteristics that were associated with deviation from a FCFS prioritization in ED rooming decisions. These findings suggest that there may be patient demographic disparities in ED rooming decisions after adjusting for clinical and ED operational characteristics.
Identification of a missense variant in the porcine AGPAT gene family associated with intramuscular fat content through whole‐genome sequencing
Authors: Molinero Eduard , Pena Ramona N. , Estany Joan , Ros‐Freixedes Roger 
Published: September 2022

AbstractThe 1‐acylglycerol‐3‐phosphate O‐acyltransferases (AGPATs) are enzymes that catalyze the conversion of lysophosphatidic acid to phosphatidic acid, which is a precursor of triacylglycerol, the main fat reservoir in mammals. We used whole‐genome sequencing of 205 pigs to identify 6639 genetic variants in the porcine AGPAT gene family. Of these, 166 common variants in the AGPAT5 gene had significant associations with fat content and composition traits. We preselected a missense single nucleotide polymorphism in exon 6 of AGPAT5 (rs196952262, A>G) for validation of its associations in 1034 pigs from the same Duroc line. The A allele showed a positive additive effect for intramuscular fat content (+1.12% ± 0.21, p < 0.001, for gluteus medius and +0.89% ± 0.33, p < 0.01, for longissimus). We also observed significant associations with fatty acid composition that were, at least in part, independent of the increased intramuscular fat. The A allele resulted in more monounsaturated fatty acids (+0.34% ± 0.15, p < 0.05, for longissimus) and a greater monounsaturated/polyunsaturated fatty acids ratio (+0.11 ± 0.04, p < 0.01, for gluteus medius and +0.13 ± 0.05, p < 0.05, for longissimus). The effect of the AGPAT5 variant on intramuscular fat was more noticeable in fatter pigs, and AGPAT5 interacts with other genes that affect overall fatness such as LEPR. AGPAT5 was the most expressed gene of the AGPAT family in pig skeletal muscle. This variant can be used as a marker in assisted selection for modulating pig fat deposition and fatty acid content.
Implementing predictive tools in surgery: A narrative review in the context of orthopaedic surgery
Authors: Zhou Yuxuan , Gould Daniel , Choong Peter , Dowsey Michelle , Schilling Chris 
Published: September 2022

AbstractClinical predictive tools are a topic gaining interest. Many tools are developed each year to predict various outcomes in medicine and surgery. However, the proportion of predictive tools that are implemented in clinical practice is small in comparison to the total number of tools developed. This narrative review presents key principles to guide the translation of predictive tools from academic bodies of work into useful tools that complement clinical practice. Our review identified the following principles: (1) identifying a clinical gap, (2) selecting a target user or population, (3) optimizing predictive tool performance, (4) externally validating predictive tools, (5) marketing and disseminating the tool, (6) navigating the challenges of integrating a tool into existing healthcare systems, and (7) developing an ongoing monitoring and evaluation strategy. Although the review focuses on examples in orthopaedic surgery, the principles can be applied to other disciplines in medicine and surgery.
Unraveling the black box of job crafting interventions: A systematic literature review and future prospects
Authors: Mukherjee Tulika , Dhar Rajib L. 
Published: September 2022

AbstractThis article offers a systematic review of empirical research intending to identify and categorise the types of existing job crafting interventions (JCIs). It highlights a range of substantial features, including methodological characteristics, intervention design and delivery characteristics, and resultant outcomes. It also attempts to uncover the mechanisms through which the interventions operate and boundary conditions determining intervention strength. Based on the results, the authors provide a conceptual framework synthesising conclusions from existing works and establish that stimulating job crafting behaviors through interventions positively impacts an array of significant outcomes. It further proposes theoretically driven recommendations for empirical and theoretical advancements in the JCI literature, accentuating the processes whereby JCIs are predicted to address contemporary workplace issues and trends.
Frequentist Model Averaging for Undirected Gaussian Graphical Models
Authors: Liu Huihang , Zhang Xinyu 
Published: September 2022

Abstract
Advances in information technologies have made network data increasingly frequent in a spectrum of big data applications, which is often explored by probabilistic graphical models. To precisely estimate the precision matrix, we propose an optimal model averaging estimator for Gaussian graphs. We prove that the proposed estimator is asymptotically optimal when candidate models are misspecified. The consistency and the asymptotic distribution of model averaging estimator, and the weight convergence are also studied when at least one correct model is included in the candidate set. Furthermore, numerical simulations and a real data analysis on yeast genetic data are conducted to illustrate that the proposed method is promising.
Clinical utility of comprehensive genomic profiling tests for advanced or metastatic solid tumor in clinical practice
Authors: Ida Hanae , Koyama Takafumi , Mizuno Takaaki , Sunami Kuniko , Kubo Takashi , Sudo Kazuki , Tao Kayoko , Hirata Makoto , Yonemori Kan , Kato Ken , Okusaka Takuji , Ohe Yuichiro , Matsui Yoshiyuki , Yamazaki Naoya , Ogawa Chitose , Kawai Akira , Narita Yoshitaka , Esaki Minoru , Yamamoto Noboru 
Published: September 2022

AbstractPrevious clinical trials indicate that 10%–25% of patients received genomically matched therapy after comprehensive genomic profiling (CGP) tests. However, the clinical utility of CGP tests has not been assessed in clinical practice. We assessed the clinical utility of CGP tests for advanced or metastatic solid tumor and determined the proportion of patients receiving genomically matched therapy among those with common and non‐common cancers. From August 2019 to July 2020, a total of 418 patients had undergone CGP tests, and the results were discussed through the molecular tumor board at our site. The median age of patients was 57 (range: 3–86) years. Colorectal cancer was the most common, with 47 (11%) patients. Actionable genomic alterations (median 3, range: 1–17) were identified in 368 (88.0%) of 418 patients. Druggable genomic alterations were determined in 196 (46.9%) of 418 patients through the molecular tumor board. Genomically matched therapy was administered as the subsequent line of therapy in 51 (12.2%) patients, which is comparable to the proportion we previously reported in a clinical trial (13.4%) (p = 0.6919). The proportion of patients receiving genomically matched therapy was significantly higher among those with common cancers (16.2%) than non‐common cancers (9.4%) (p = 0.0365). Genomically matched therapy after the CGP tests was administered to 12.2% of patients, which is similar to the proportion reported in the previous clinical trials. The clinical utility of CGP tests in patients with common cancers greatly exceeded that in patients with non‐common cancers.
Executive function measurement in urban schools: Exploring links between performance‐based metrics and teacher ratings
Authors: Zonneveld Annie K. , Serpell Zewelanji , Parr Teresa , Ellefson Michelle R. 
Published: September 2022

AbstractWhen compared to research centered on the executive function development of white, middle‐class children, relatively little is known about their non‐white, low socioeconomic status peers. In an effort to harmonize how executive functions are measured within under‐represented contexts, the present study addresses gaps in the evaluation of everyday executive functioning to better understand whether behavior rating scales completed by teachers (BASC2EF – BASC executive function scale, 2nd edition; BASC3EF – BASC executive function scale, 3rd edition) capture distinctions between performance‐based measures. This study includes two large samples of older, ethnic minority children from high‐poverty backgrounds (Sample 1. N = 243; Mage = 9.28 years, SDage = 0.80; nfemale = 125; nAfricanAmerican = 216, nLatinAmerican = 15, nAsianAmerican = 6; Sample 2. N = 229; Mage = 10.02 years, SDage = 1.01; nfemale = 120; nAfricanAmerican = 132, nLatinAmerican = 92, nWhite = 3, nPacificIslander = 1). Based on structural equation models testing the links between computerized performance‐based measures and the teacher rating scales, the results indicate that BASC2EF in its original form might be a good fit for some populations but there is not a strong factor structure for the current high‐poverty samples. In addition, post‐hoc analyses suggest that only including BASC2EF items also in BASC3EF or using BASC3EF is best practice for high‐poverty populations. BASC3EF seems better able to capture different components of performance‐driven tasks, whereas BASC2EF captures overall executive functioning better than individual tasks. These findings encourage continued questioning surrounding metrics used to assess everyday executive functions in older children from diverse backgrounds.Highlights
This study explores whether teacher ratings of children's everyday executive functioning (using standardized behavior rating scales) capture distinctions between performance‐based measures.
Results indicate that BASC2EF teacher rating scale (Karr & Garcia‐Barrera, 2017) is not a good representation of everyday executive function behaviors by children from schools in high‐poverty communities.
The findings suggest that restricting BASC2EF analyses to only items included in BASC3EF (Reynolds & Kamphaus, 2015) or using BASC3EF for high‐poverty populations.
BASC3EF seems better able to capture the different components of performance‐driven tasks, whereas BASC2EF captures overall executive functioning better than individual tasks.
Time to exceed pre‐randomization monthly seizure count for perampanel in participants with primary generalized tonic–clonic seizures: A potential clinical end point
Authors: Kerr Wesley T. , Brandt Christian , Ngo Leock Y. , Patten Anna , Cheng Jocelyn Y. , Kramer Lynn , French Jacqueline A. 
Published: September 2022

AbstractObjectiveTo evaluate the exploratory time to exceed pre‐randomization seizure count (T‐PSC) in the determination of efficacy of adjunctive perampanel in participants with primary generalized tonic–clonic (PGTC) seizures in generalized‐onset epilepsy.MethodsIn this multicenter, double‐blind study (ClinicalTrials.gov identifier: NCT01393743), participants ≥12 years of age with treatment‐resistant idiopathic generalized epilepsy were randomized to receive placebo or adjunctive perampanel (≤8 mg/day) across a 17‐week double‐blind treatment phase (4‐week titration; 13‐week maintenance). We evaluated the pre‐planned exploratory end point of the T‐PSC using a Kaplan–Meier analysis. We also re‐evaluated the correspondence of the primary end points of median percent seizure frequency change (MPC) and 50% responder rate (50RR) calculated at T‐PSC and at the end of the trial.ResultsThe exploratory end point of median T‐PSC on placebo was 43 days and >120 days on perampanel (log‐rank p < .001). The primary end points calculated at T‐PSC did not differ significantly from the end points at the end of the trial (MPC −31% vs −42% at T‐PSC; 50RR 32% vs 51% at T‐PSC). After T‐PSC was reached, participants had a median (interquartile range) of 5 (3–13) additional seizures on placebo and 5 (2–10) on perampanel.SignificanceThe exploratory end point of T‐PSC demonstrated the effectiveness of perampanel despite a shorter duration of monitoring. The seizures that occurred after T‐PSC did not influence the conclusions of the trial; therefore, T‐PSC may be a viable alternative to traditional trial end points that reduces the risk to participants.
Are financial derivatives related to intra‐entities' tax aggressiveness? UK evidence
Authors: Boussaidi Ahmed , Chkir Imed , Hussainey Khaled , Sidhom‐Hamed Mounira 
Published: September 2022

AbstractThis study investigates the effect of hedged versus nonhedged financial derivative instruments on the intra‐entities' tax aggressiveness. Our findings provide evidence that multinational enterprises manage derivatives instruments to avoid their tax expenses aggressively. Specifically, nonhedged derivatives are an excellent determinant of the tax aggressiveness practices of corporate groups. Besides, this study speaks to the central role of governance quality in mitigating this aspect of tax aggressiveness and provides practical guidance to tax authorities and regulators for establishing new policies for governing financial derivative instruments and preventing tax aggressiveness from negatively affecting firms and society.
Evidence for evolutionary adaptation of mixotrophic nanoflagellates to warmer temperatures
Authors: Lepori‐Bui Michelle , Paight Christopher , Eberhard Ean , Mertz Conner M. , Moeller Holly V. 
Published: September 2022

AbstractMixotrophs, organisms that combine photosynthesis and heterotrophy to gain energy, play an important role in global biogeochemical cycles. Metabolic theory predicts that mixotrophs will become more heterotrophic with rising temperatures, potentially creating a positive feedback loop that accelerates carbon dioxide accumulation in the atmosphere. Studies testing this theory have focused on phenotypically plastic (short‐term, non‐evolutionary) thermal responses of mixotrophs. However, as small organisms with short generation times and large population sizes, mixotrophs may rapidly evolve in response to climate change. Here, we present data from a 3‐year experiment quantifying the evolutionary response of two mixotrophic nanoflagellates to temperature. We found evidence for adaptive evolution (increased growth rates in evolved relative to acclimated lineages) in the obligately phototrophic strain, but not in the facultative phototroph. All lineages showed trends of increased carbon use efficiency, flattening of thermal reaction norms, and a return to homeostatic gene expression. Generally, mixotrophs evolved reduced photosynthesis and higher grazing with increased temperatures, suggesting that evolution may act to exacerbate mixotrophs' effects on global carbon cycling.