bluuebunny/crossref_metadata_2025_split huggingface dataset:
Not a trifecta: complementary use of carotid artery revascularization techniques in the era of hybrid neurosurgery
Authors: Levy Bennett R. , Waqas Muhammad , Monteiro Andre , Cappuzzo Justin M. , Baig Ammad A. , Khawar Wasiq I. , Davies Jason M. , Snyder Kenneth V. , Siddiqui Adnan H. , Riina Howard A. , Levy Elad I. 
Published: May 2022

OBJECTIVE
Carotid stenosis is currently treated by carotid endarterectomy (CEA), carotid artery stenting (CAS), or transcarotid artery revascularization (TCAR). This study sought to add to the literature by providing real-world data comparing the safety and effectiveness associated with the performance of these carotid revascularization techniques by dual-trained neurosurgeons.

METHODS
The authors performed a retrospective review of carotid stenosis databases at two US centers. Patients treated by CEA, transfemoral CAS, or TCAR for atherosclerotic carotid artery disease were included. Clinical outcomes were compared at 30 days after the procedure.

RESULTS
Seven hundred eighty patients were included (583 with CAS, 165 with CEA, and 32 with TCAR). Overall, 486 patients (62.3%) were men, and 393 (50.4%) had left-sided carotid stenosis. Most patients (n = 617, 79.1%) had symptomatic disease. Among the three treatment groups, there were no statistically significant differences with respect to 30-day ischemic events (CAS 3.8%, CEA 1.8%, TCAR 6.3%; p = 0.267) or 30-day mortality rates (CAS 3.6%, CEA 2.4%, TCAR 3.1%; p = 0.857). Male sex had significantly lower odds of 30-day transient ischemic attack (TIA) or stroke in both univariable (p = 0.024) and multivariable (p = 0.023) regression models. Increasing age had significantly higher odds of 30-day mortality on univariable (p = 0.006) and multivariable (p = 0.003) regression. Patients with the occurrence of 30-day TIA or stroke also had significantly higher odds of 30-day mortality on univariable (p < 0.001) and multivariable (p < 0.001) regression.

CONCLUSIONS
This real-world experience reflects the current practice of hybrid neurosurgery at two high-volume tertiary care centers and suggests that all three treatment modalities have comparable safety and effectiveness if patients are properly selected.
150 Years Anniversary of the Church and Archaeological Office - Museum of the Moscow Theological Academy
Authors: Григорьева Наталья Ивановна 
Published: May 2022

Цель данной работы - хронологически выстроить события, связанные с возникновением музея в стенах Московской духовной академии, определить их значимость для формирования музейного собрания, а также показать вклад профессоров Академии в разработку его концепции и формирование экспозиций. Основным материалом для изучения указанных вопросов стали монографии, статьи в периодической печати дореволюционного периода, материалы архивов библиотеки Московской духовной академии. Публикаций, посвящённых истории музея дореволюционного периода, существует весьма немного ввиду малоизученности источников, а также наличия источников, не введённых в научный оборот на сегодняшний день. Настоящее исследование в некоторой степени восполняет этот пробел. В статье приводятся факты из источников и публикаций, раскрывающие смысл 1871 г. для истории Церковно-археологического кабинета Московской духовной академии.
The purpose of this work is to chronologically line up the events associated with the emergence of the museum within the walls of the Moscow Theological Academy, determine their signi cance for the formation of the museum collection, and also show the contribution of the professors of the Academy to the development of its concept and the formation of expositions. Monographs, articles in periodicals of the pre-revolutionary period, materials from the archives of the library of the Moscow Theological Academy became the main material for studying these issues. There are very few publications devoted to the history of the museum of the pre-revolutionary period due to the insuf ciently studied sources, as well as the presence of sources that have not been introduced into scienti c circulation today. The present study lls this gap to some extent. The article presents facts from sources and publications that reveal the meaning of 1871 for the history of the Church and Archaeological Cabinet of the Moscow Theological Academy.
Three Views on the Past and Future of Russia - Westerning, Eurasianism, Soilism
Authors: Горюнов Алексей Владимирович 
Published: May 2022

Статья посвящёна анализу исторической и социокультурной специфики России как локальной цивилизации. В работе анализируется социокультурная структура Российской цивилизации, выделяются такие её сегменты, как «социокультурное ядро», «внутренний Восток», «внутренний Запад»; выделяются такие направления общественной мысли, как «западничество», «евразийство» и «почвенничество». Также показывается, что указанная структура Российской цивилизации обусловлена спецификой её исторического пути. В завершающей части работы на примере полемики Н. А. Бердяева и Л. П. Карсавина анализируются различия во взглядах на русскую историю представителей указанных направлений.
The article is devoted to the analysis of the historical and socio-cultural speci cs of Russia as a local civilization. The paper analyzes the socio-cultural structure of the Russian civilization, highlights its segments such as «socio-cultural core», «inner east», «inner west», highlights such areas of social thought as «Westernism», «Eurasianism» and «Soilism». It is also shown that the speci ed structure of the Russian civilization is due to the speci cs of its historical path. In the nal part of the work, on the example of the polemics of N. A. Berdyaev and L. P. Karsavin, the differences in the views on Russian history of representatives of these trends are analyzed.
Retinal examination with curcumin in Alzheimer's disease
Authors: Kayabasi Umur A. , Cekmeceli Selçuk N. 
Published: May 2022

Background: Currently there is no definite cure for Alzheimer's therefore early detection is critical. Undetected Alzheimer's Disease (AD) can lead to severe accidents, neglecting to take essential medications, injury to oneself or others, and/or financial problems. Currently, biomarkers are the most promising way to detect Alzheimer's early on. Biomarkers such as beta-amyloid and tau levels taken through invasive mehods or brain scans that involve radiation are among them [20]. Objectives: Alzheimer's Disease (AD) presents itself in the body with an increase in ß-amyloid (Aß) plaque deposition, neurofibrillary tangle formation (NFT), and inflammation. As the retina is an extension of the brain and the brain structure it is possible to detect misfolded proteins via retinal examination non-invasively. One of the main objectives of this study is to determine the effectiveness of curcumin which is a phytochemical which can bind to amyloid-beta and Tau and can be used both for the diagnosis and early treatment of AD. The aim of this study was to discover the binding property of curcumin to both Tau and AB in the retina as a potential biomarker for AD.Methods: In this study, 20 patients were invited with mild AD who had undergone retinal examination within the past 2 years. All the patients had retinal imaging with curcumin which revealed misfolded proteins during the examination and then they were advised to take daily curcumin. The mean age of the patients was 71, and the patients were instructed to take Curcumin Meriva in 500 mg supplements once daily after their prior examinations. All patients had tests repeated with FAF and Heidelberg Spectralis OCT device. The regions with abnormal lesions on FAF were detected and the layer of the defect was scanned by OCT plus compared with the previous imaging of the patients. The images were examined in a masked fashion by 2 specialists.Results: The images disclosed hyperfluorescent lesions on FAF and OCT revealed accumulations in the inner layers of the retina. Some accumulations had dot shapes and others had fibril-tangle shapes. Some lesions were present in prior exams, but they were more pronounced and shinier after curcumin use. Their size and shape were in concordance with misfolded proteins in the brain [Fig.2,3,4,5,6].Conclusion: Retinal examination with curcumin revealed AB plaques in the retina in prior studies. Our study is the first that may demonstrate an easy way to detect the culprit plaque Tau inside the retina of live patients. Keywords: Alzheimer's Disease, curcumin, neurofibrillary tangle formation (NFT), inflammation, retina, ß-amyloid (Aß) plaque deposition, Misfolded proteins, Fundus Autofluorescence (FAF), Tau, amyloid-beta, treatment
ANALISIS USAHA TAHU DI KADEMANGAN KABUPATEN BLITAR
Authors: Ramadhan Muneeb , Aditya P Luhur 
Published: May 2022

Penelitian bertujuan untuk mengetahui nkeuntungan dan kelayakann usaha produksi tahu di Kademangan Kabupaten Blitar. Metode pengolahan data dilakukan dengan nmenggunakan metode kualitatif dan kuantitatif. Hasil penelitian menunjukan bahwa (1) Total penerimaan sebesar Rp 3.180.975.000 per tahun dan total biaya sebesar Rp 2.958.744,600 per tahun. (2) Kelayakan agroindustri tahu layak untuk diusahakan, karena hasil dari analisis R/C Ratio yang didapat adalah 1,075 (R/C Ratio > 1) (3) Berdasarkan hasil analisis BEP produksi harus dapat memproduksi minimal 1.616.186,0465 potong dan 11,904,4 karung untuk mencapai titik impas, dan hasil produksi yang dihasilkan usaha industri tahu adalah 1.737.400 potong dan12.775 karung limbah / tahun. 4) Penerapan GMP (Good Manufacturing Practices) meliputi : lokasi, bangunan, fasilitas sanitasi, pengawasannproses, karyawan, nlabel atau keterangan produk, penyimpanan, pemeliharaan dan program sanitasi, dokumentasi dan pencatatan, npelatihan. 5) HACCP dan menganalisis usaha produksi tahu di Kademangan Blitar menetapkan titik kendali kritis CC.
This study aims to determine the advantages and feasibility of tofu production business in Kademangan, Blitar Regency. The data processing method is qualitative and quantitative methods. The results of the study show that 1) Total revenue is Rp. 3,180,975,000 per year, total cost is Rp. 2,958,744,600 per year. 2) Feasibility of the tofu agroindustry is feasible, because the results of the R/C Ratio analysis obtained are 1.075 (R/C Ratio > 1) 3) Based on the results of the BEP analysis, production must be able to produce a minimum of 1,616,186.0465 pieces and 11,904.4 sacks to break even, and the production results of the tofu industry are 1,737,400 pieces and 12,775 sacks of waste/year. 4) The application of GMP (Good Manufacturing Practices) includes: location, building, sanitation facilities, process supervision, employees, product labeling or description, storage, maintenance and sanitation programs, documentation and recording, training. 5) HACCP and analyze the tofu production business in Kademangan Blitarn to determine the critical point of CC.
Selection of the rational geometry of specimen for compression test
Authors: Borysevych Volodymyr , Zhang Xiang , Chen Jingming 
Published: May 2022

The object of study in this article is the conditions during the compression test. The subject matter is the models that simulate the physical processes during the compression test. The goal is to obtain models, which allow obtaining real information about stress-strain dependence during compression. The tasks to solve are to develop a three-dimensional computer model of a specimen subjected to compression that geometry allows to avoid the nonuniform distribution of stress-strain state. The upsetting of cylindrical specimens is one of the most commonly used methods for compression tests. However, due to the frictional force on both ends of the specimen, a barreling shape is likely to appear in the middle of the cylinder during the compression process, resulting in inaccurate mechanical properties of the final measured specimens. Therefore, this paper conducts qualitative and quantitative research on the physical parameters that affect the degree of barreling during the upsetting process of cylindrical specimens. The following results were obtained. The Concave End Face (CEF)-Upsetting and Headed Specimen (HS)-Upsetting methods have a significant effect on reducing the barreling degree. The smallest difference in the barreling degree is almost close to 101.8 % that appears in the CEF-Upsetting. Further analysis shows that the above two methods have similar principles for reducing the barreling degree, and both reduce the barreling degree in the middle by increasing the deformation of the workpiece ends. Then, the influence of the deformation of the workpiece head zone on the deformation of the non-end (gauge length) zone is analyzed. The rounded corners of the transition zone between the workpiece end zone and the non-end zones of HS-Upsetting have a great influence on the generation of forming defects. The end face groove size of CEF-Upsetting has a significant effect on the barreling degree after upsetting. Under the same other conditions, the barreling degree is the smallest when the ratio of the concave depth (a/D) is 0.12, when the ratio of the concave diameter(Dc/D) doesn’t exceed 0.6, the smaller the ratio of the concave diameter(Dc/D), the smaller the barreling degree. Finally, through the design of the orthogonal test, the functional relationship between the barreling degree and the dimension parameters of the workpiece ends zone is established. Conclusions: It doesn’t prove the feasibility of barreling-less upsetting only, but also provides theoretical support for actual production in the future.
Моделювання умов отримання наноструктур в алюмінієвих сплавах при дії іонізуючого випромінювання
Authors: Широкий Юрій Вячеславович , Сисоєв Юрій Олександрович , Постельник Тетяна Олександрівна 
Published: May 2022

The use of laser radiation as a source of ionizing radiation to obtain nanostructured and submicrostructured layers on aluminum alloys requires the determination of the necessary technological parameters. Therefore, a theoretical study of ionizing radiation on aluminum alloy AK8 was conducted according to the previously proposed model. When choosing the region in the material of the aluminum alloy, where nanostructures can be formed under the action of ionizing radiation, apply different lengths of ions. Because of the theoretical study of the formation of nanostructures in the surface layer of the aluminum alloy AK8, the temperature distribution in the zone of ionizing radiation at different depths of the material was obtained. Temperature fields for different heat flux densities q1 = 106 W/m2 and q2 = 105 W/m2 were also constructed. The obtained temperature fields for heat flux q1 showed that with increasing depth of the material, the temperature decreases from 2480 to 650 K. The values of maximum temperatures on the material surface are slightly higher than necessary to obtain nanostructures at lower depths maximum temperatures decrease to nanostructures can be realized. Simultaneously, under the action of heat flux q2 = 105 W/m2, the maximum surface temperature decreased to values of 1950 K, and at depth it was 550 K. and was equal to 106 K/s at q2. All these confirmed the possibility of creating conditions for the formation of nanostructures. Due to the temperature range obtained from the calculated temperature fields, the depths of the aluminum alloy where nanostructures can be formed were determined. Studies of the effect of laser radiation spot size on the surface of the material on the formation of nanostructures were also conducted, which showed that when exposed to a spot size of 3 · 103 to 10-3 m, the possibility of nanostructures is significantly reduced, while reducing the spot size to 10-4 m leads to a significant increase in the possibility of forming nanostructures. To estimate the possible volume of nanostructures, the dependence of the nanocluster size on the heat flux density in the range from 107 to 1010 W / m2 and its action time in the range from 10-9 to 10-3 s were considered. The dependence of the maximum temperature on the heat flux density and the time of its action is also constructed. All this allows you to choose the technological parameters of laser radiation to obtain nanostructured layers on aluminum alloys, and the ability to determine the size of nanostructures allows you to predict the physical and mechanical characteristics of the surface layers of processing materials. These studies may be of interest to specialists in strengthening the surfaces of aluminum alloys and further studies of nanostructures.
Urgensi Keberadaan Buku Panduan Penelitian Biologi Molekuler Menggunakan Drosophila melanogaster
Authors: Fatmawati Diani , Saleem Maryam , Hindun Iin , Permatasari Indah , Solikhah Solikhah , Khoiroh Diana , Fauzi Ahmad 
Published: May 2022

Kehadiran buku panduan praktikum memiliki urgensi yang tinggi pada perkuliahan biologi molekuler Drosophila melanogaster merupakan organisme model paling populer di bidang biologi namun pemanfaatannya di Indonesia masih jauh dari optimal. Tujuan penelitian ini adalah menganalisis kebutuhan terkait pentingnya kehadiran buku panduan penelitian biologi molekuler berbasis pemanfaatan D. melanogaster. Mahasiswa Biologi dari universitas di Malang dilibatkan sebagai respoden penelitian. Kuesioner digunakan sebagai instrumen pengumpulan data dalam penelitian ini. Analisis data menggunakan statistika deskriptif dan menggunakan perform assessment chart. Hasil penelitian menginformasikan mayoritas mahasiswa memiliki kompetensi meneliti yang rendah. Analisis perform assessment chart menghasilkan dua purpose statement, yaitu dibutuhkannya buku panduan yang dapat melatih mahasiswa merancang hingga melaporkan penelitian dan dibutuhkannya panduan penelitian genetika molekuler. Oleh karena itu, keberadaan buku panduan penelitian molekuler yang dapat memandu mahasiswa melakukan penelitian perlu dikembangkanKeywords: Drosophila melanogaster, Genetika molekuler, Inkuiri, Keterampilan meneliti, Lalat buah
HERIYADI HARIS: BIOGRAFI DAN PROSES KREATIF DI SANGGAR PERPEKINDO
Authors: Khairuz Zulfa  
Published: May 2022

Abstrak: Penelitian ini bertujuan untuk (1)Mendeskripsikan riwayat perjalanan hidup Heriyadi Haris sebagai seniman tari, (2)Mendeskripsikan Proses Kreatif Heriyadi Haris sebagai seniman tari di Sanggar PERPEKINDO dan (3) Mendeskripsikan hasil karya dan prestasi Heriyadi Haris sebagai seorang seniman tari. Metode yang digunakan adalah metode kualitatif. Teknik pengumpulan data menggunakan teknik observasi, wawancara dan dokumen. Hasil penelitian yang didapat adalah (1) Perjalanan Heriyadi Haris sebagai seniman tari cukup unik selama 40 tahun, beralihnya profesi dari atlit menjadi seorang seniman tari disebabkan karena telah ada ketertarikan terhadap kesenian sejak masa kecilnya, menurutnya tari tidak dibatasi usia dan memiliki sesuatu keindahan yang mampu mengangkat nama daerah sendiri. Tahun 1981 bergabung dengan sanggar PERPEKINDO, ketekunannya menjadikan dirinya seorang penari hingga koreografer bahkan menjadi pimpinan sanggar tersebut pada tahun 2003. (2)Karakter dalam proses kreatifnya dipengaruhi kepribadiannya yang komunikatif, kooperatif dan selalu melibatkan anggota sanggar PERPEKINDO. Melalui 4 tahapan yaitu persiapan, inkubasi, iluminasi dan verifikasi atau evaluasi. (3). Tahun 2011 menerima Borneo Award sebagai seniman tari di Kalimantan Selatan. Karya tari yang pernah diciptakan selalu berlatar budaya lokal baik Banjar atau Dayak yang ada di Kalimantan Selatan. Sekitar 40 karya,diantaranya telah mendapat berbagai prestasi dan ditampilkan ditingkat regional,nasional,serta internasional.
EKSISTENSI TARI DROP DARUET DARI ACEH PIDIE DAN UPAYA PELESTARIAN DI ERA MODERNISASI
Authors: Gusmail Sabri , Anwar Khairul 
Published: May 2022

Tari Drop Daruet sebagai warisan peristiwa budaya daerah masih bertahan hingga saat ini. Tujuan penelitian ini adalah untuk mengetahui eksistensi tari Drop Daruet dan mengetahui upaya pelestariannya di era modernisasi. Lokasi penelitian di sanggar Cut Nyak Dhien Meligoe Gubernur Aceh. Jenis penelitian ini adalah penelitian kualitatif dengan metode studi kasus. Permasalahan dalam penelitian ini yaitu: 1) Bagaimana eksistensi Tari Drop Daruet, 2) Upaya Sanggar Cut Nyak Dhien Meuligoe Gubernur Aceh dalam mempertahankan Tari Drop Daruet di era modernisasi. Sumber data utama diperoleh dari wawancara dengan informan, sedangkan sumber data lainnya diperoleh dari observasi dan studi dokumentasi. Teknik pengumpulan data menggunakan observasi dan wawancara mendalam dengan informan (pengurus, pelatih, penari, pemusik dan masyarakat). Teknik analisis menggunakan model analisis data interaktif yakni pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan. Mengacu pada teori Malinowski yang mengatakan budaya yang lebih tinggi dan aktif akan mempengaruhi budaya yang lebih rendah dan pasif melalui kontak budaya. Serta Umar Kayam terkait tentang kesenian dan peran masyarakat pendukungnya. Hasil penelitian menunjukkan bahwa tari Drop Daruet merupakan tari tradisi yang tidak banyak dikenal oleh masyarakat dan minimnya informasi akan keberadaan tari tersebut. Tari Drop Daruet diartikan sebagai bentuk seni yang berakar dan bersumber serta dirasakan sebagai milik sendiri oleh sanggar Cut Nyak Dhien Meuligoe Gubernur Aceh atau lingkungannya. Upaya yang dilakukan dalam pengelolaan tari tersebut hanya didasarkan pada kesadaran masyarakat pendukungnya yang dilakukan dari waktu ke waktu dan diwariskan secara regenerasi.
NILAI ESTETIKA DALAM TARI LENGGER PUNJEN DI DUSUN GIYANTI DESA KADIPATEN KECAMATAN SELOMERTO KABUPATEN WONOSOBO
Authors: Taranggana Haki Wanudya 
Published: May 2022

Penelitian ini bertujuan mendeskripsikan nilai estetika dalam Tari Lengger Punjen di Dusun Giyanti Desa Kadipaten Kecamatan Selomerto Kabupaten Wonosobo. Jenis penelitian kualitatif yang bersifat deskriptif. Pengumpulan data menggunakan observasi, wawancara mendalam, dan studi dokumentasi. Data yang telah terkumpul dianalisis kemudian ditarik kesimpulan, uji keabsahan data dengan metode triangulasi sumber. Hasil penelitian: 1. Tari Lengger Punjen merupakan tari yang diciptakan untuk membuat nuansa baru pada kesenian lengger, berfungsi sebagai hiburan, seni pertunjukan dan upacara. 2. Nilai estetika Tari Lengger Punjen dilihat dari unsur-unsur estetika yaitu wujud (bentuk dan struktur), terdapat bentuk intrance dan punjen (diangkat di bahu) serta struktur gerak murni dan gerak maknawi, bobot ditunjukkan pada suasana yang hikmat menggambarkan keluarga dan kematian, gagasan terinspirasi dari bentuk Tari Bondhan Kendi dengan pesan berisi pesan religius dan nasihat, penampilan ditunjukkan pada bakat dan keterampilan yang harus dilatih rutin dan sarana sebagai penunjang penampilan. 3. Nilai estetika Tari Lengger Punjen dapat dilihat dari prinsip nilai estetika yaitu keserasian melalui jumlah penari (berpasangan), rias busana, gerak, serta properti, keseimbangan melalui gerak pada saat dipunjen (diangkat di bahu), kekontrasan dilihat sangat mencolok dari pengembangan gerak tangan jika ditarikan oleh beberapa pasang penari karena tidak terlihat keserasian gerak antar penari. Kerumitan melalui atraksi mengangkat penari putri (munji).