bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrospective study of mineral pollution in the Tshamilemba district of the City of Lubumbashi, DR Congo
Authors: Ramazani Ben Sadiki , Mpanga Fabien Ilunga , Lutandula⃰ Michel Shengo 
Published: November 2022

Abstract
Since 2002, Thamilemba quarter, located in the City of Lubumbashi (DRC), is a home to mining activities for the hydrometallurgical extraction of copper and cobalt. Consequently, great amounts of mineral wastes were improperly stored resulting in toxic metals liberation and contamination of the surrounding soil and the near to surface waters. This research determined major physicochemical parameters and measured the trace metal elements (TMEs) concentrations in samples of soil, water and plants. Based on data given by the samples analysis, it established the spatial distributions of metals in both the upper and deep soil (20 cm) through the data mathematical processing with the Matlab 7.1 software. The samples analysis results were compared to quality standards to ascertain the population's fear about the environment pollution is justified or not. An average pH value of 7.69 was measured in the soil and a value of 9.1 in whitish substances found at some spots. The soil samples presented TMEs concentrations above standards (0.5 mg/kg) or phytotoxic levels in the upper soil layers (Co, Cu, Fe and Zn) and in the deep layers (Co, Cu, Fe, Zn and Pb). Water samples contained TMEs to concentrations (Cu, Co, Mn, Zn and Pb) greater than drinking water quality standards set by the World Health Organization (WHO). The plant samples contained TMEs to high levels: Saccharum officinarum (Co, Cd, Ni, Mg and Pb) and in Musa acuminate (Co, Cd, Ni, Mn, Zn and Pb). These findings show that toxic metals endanger the wildlife and human health and confirm the population fears about the environment deterioration.
Longitudinal analysis of influenza vaccination implicates regulation of RIG-I signaling by DNA methylation
Authors: Fu Hongxiang , Pickering Harry , Rubbi Liudmilla , Ross Ted M. , Reed Elaine F. , Pellegrini Matteo 
Published: November 2022

Abstract

BackgroundInfluenza virus infection alters the promoter DNA methylation of key immune response-related genes, including type-1 interferons and proinflammatory cytokines. However, less is known about the effect of the influenza vaccine on the epigenome. We utilized a targeted DNA methylation approach to study the longitudinal effects (day 0 pre-vaccination and day 28 post-vaccination) on influenza vaccination responses in peripheral blood mononuclear cells.ResultsWe found that baseline, pre-vaccination methylation profiles are associated with pre-existing, protective serological immunity. Additionally, we identified 481 sites that were differentially methylated between baseline and day 28 post-vaccination. These were enriched for genes involved in the regulation of the RIG-I signaling pathway, an important regulator of viral responses.ConclusionsOur results suggest that DNA methylation changes to components of the RIG-I pathway are associated with vaccine effectiveness. Therefore, immunization strategies that target this pathway may improve serological responses to influenza vaccination.
Detail design (DD), front end (FE), back end (BE) design of non-tactical deployable 20 GWh (17.20841 kilo ton TNT) plane wave lens configuration fusion device
Authors: Rafique Muhammad Musaddique Ali 
Published: November 2022

Abstract
A simple plane wave lens, using an inert central plastic wave shaper, has been designed. An experiment was done with a 4 in diam, zeroth order design. An iterative technique that uses measured time deviations to connect the next wave shape was developed. Two identical versions of the first iterated shape were fired. Arrival time deviations in these first iterates fell within 50 ns bonds. With greater care and further iterations, lenses bound by 10 ns deviations seem possible. An advanced and novel integration method is applied. It is shown that this technique bears significant advantage over prior methods and is meritorious.
Continuous noninvasive monitoring of the hemoglobin during cardiac surgery and comparative analysis with existing technique
Authors: Khaleelullah Mohamed Mathar Sahib Ibrahim , Kawashima Shingo , Morita Koji , Mimuro Soichiro , Kurita Tadayoshi , Nakajima Yoshiki 
Published: November 2022

Abstract
Hemoglobin (Hb) concentration monitoring is the most required analysis during surgery and critical care treatment to make proper decision regarding blood transfusion. Blood gas analysis is required invasive intermittent blood sampling. Various non-invasive Hb monitoring techniques are under research for better real time patients’ management. Masimo rainbow® Pulse CO-Oximeter® is to monitor continuous and noninvasive hemoglobin (SpHb) whereas blood samples give intermittent results. Recently, disposable SpHb sensor has been updated. We evaluate the SpHb sensor compared with total Hemoglobin(tHb) in patients undergoing cardiac surgery using cardiopulmonary bypass (CPB).
A total of 272 SpHb and tHb paired data samples from 60 patients. To analyze the tHb, the patients’ blood samples were drawn intermittently by the radial arterial line and blood gas analyzer ABL 90 (Radiometer corp., Denmark) as per anesthesiologist decision. SpHb sensors (RD rainbow SET-2 Adt sensor, Masimo Corp., USA) were attached to the patients’ ring finger connected to Root® with Radical-7®. Reliability and trending ability between the SpHb and tHb were analyzed by the regression analysis, Bland-Altman analysis, four quadrant plots and polar plot. Limits of agreement between SpHb and tHb is calculated to be -2.01 to 2.2 g/dL with a bias of 0.13 g/dL. The correlation coefficient (r) of SpHb and tHb were 0.8036. Concordance ratio of four quadrant and polar plots were 93% and 91%, respectively.
Both Absolute and trend accuracy of SpHb with the latest version are clinically acceptable in patients undergo cardiac surgery using CPB.
A Hybrid Feature Method for Early Fake News Detection via Event Categorizer
Authors: Zhao Buze , Deng Hai , Hao Jie 
Published: November 2022

Abstract
Fake news detection with hybrid features has attracted a great dealof attention due to its great potential in preventing the spread offake information in social media, and it has become an importanttask to be addressed due to many negative effects such as reader misleading, economic recession and political volatility. In this paper, wepropose an event categorizer-based neural network (HECNN) framework for hybrid feature fake news detection, which combines a hybridfeature extractor and an event categorizer to extract transferable features of different events for fake news detection. Moreover, we extracta series of features from text, visual text, visuals, and user profilesfor fake news detection. The experimental results show that the proposed HECNN model improves the accuracy and F1 score comparedto the baseline as well as other advanced deep learning methods.
Awareness about post-mortem eye donation among students of the Syrian Private University
Authors: Alameddin Ammar , Dugha Ghaith , Salman Afraa 
Published: November 2022

Abstract
Background
Eye donation (corneal donation) is the process of screening a corneal donor, recovering the corneal tissue, and preparing it for transplant. People who benefit from corneal donation are those who suffer from corneal blindness. This study aims at assessing the awareness of eye donation among students of the Syrian Private University of various faculties and their readiness for post-mortem eye donation
Methods
A student-based cross-sectional study was conducted in faculties of the Syrian Private University. A total of 538 students between the ages of 18 and 36 were selected. After obtaining informed written consent, knowledge regarding eye donation was assessed through a pre-designed closed questionnaire. The questionnaire was drafted to understand the sociodemographic factors that influence the desire to donate and the awareness of eye donation in this category of community members.
Results
The mean age of the participants was 21.48 ± 2.45 years. 61% of the participants were females while 39% were males. 75% of the participants heard of eye donation. 65% were aware of post-mortem eye donation. 39% of the participants knew that there is a certain age for eye donation, and 85% believed that corneal diseases can lead to blindness. 303 students knew that Keratoplasty is performed in Syria while 235 students didn’t know. 36% of the participants wanted to donate eyes after death, while 64% refused. The branch of the study was an important determining factor in terms of knowing eye donation, as the largest percentage of students who wanted to donate eyes after death were from the faculty of medicine (P = 0.0144).
Conclusion
Despite the relatively good knowledge and awareness ratios among students, they were among the students of the medical branches, which indicates the lack of knowledge and awareness about the donation of eyes among the students of the rest of the faculties, which calls for a rethinking of ways to raise knowledge and awareness among all students in different branches of study.
Recipient independent high accuracy FMT prediction and optimization in mice and humans
Authors: Shtossel Oshrit , Turjeman Sondra , Riumin Alona , Goldberg Michael R. , Elizur Arnon , Mor Hadar , Koren Omry , Louzoun Yoram 
Published: November 2022

Abstract
Background Some microbiome composition can be associated with negative outcomes, including among others, obesity, disease and the failure to respond to treatment. Microbiota manipulation or supplementation have been argued to restore the microbiome associated with a healthy condition. Fecal Microbiota Transplantation (FMT) is among the most popular microbiome intervention procedures. Current practices are to choose the transplanted microbiome based on the donor phenotype, and not based on the expected recipient phenotype. However, the two differ drastically. We here propose an algorithm to predict the expected outcome of FMT from the donor phenotype, and optimize the FMT for different required outcomes.
Results We here show, using multiple microbiome properties, that the donor and recipient phenotypes differ widely, and propose a tool to predict the recipient phenotype after the FMT using only the donors' microbiome and when available demographics for transplants from humans to either antibiotic treated mice, or other humans. We then extend the method to optimize the best-planned transplant (bacterial cocktails) by combining the predictor and a genetic algorithm (GA). We validate the predictor using a de-novo FMT experiment highlighting the possibility to choose transplants that optimize an array of required goals. We further show that a limited number of taxa is enough to produce an optimal FMT.
Conclusions Over the shelf FMT require recipient independent optimized FMT selection. Such a transplant can be from an optimal donor, or from a cultured set of microbes. We have here shown the feasibility of both types of donations in antibiotic treated mice and for transplants between humans.
Partial Discharge Signal De-noising in Power Transformer by Applying Radial Basis Function Network
Authors: Khavari Ehsan , Hosseini S. M. Hassan Hosseini , Gharehpetian Gevork B. 
Published: November 2022

Abstract
The noise interferes with the measuring equipment installed in transformer stations and results in technical challenges for utility engineers. Sensors are mounted on transformers, to measure partial discharge (PD) signals, but the noise deforms the PD signals. In this paper, the noise removal from PD signal of power transformers is performed by a radial basis function (RBF) neural network. The CST software is used to simulate a transformer, PD and noise. Also, a laboratory model is used to generate the PD and noise signals. The simulation and measurement results are presented and discussed. It is shown that the proposed method is a good technique for noise removal from PD signals.
A two-phase branch-and-bound algorithm for seru scheduling problems with sequence-dependent setup time
Authors: Zhang Xiaohong , Zhang Zhe , Gong Xue , Yin Yong 
Published: November 2022

Abstract
This paper focuses on seru scheduling problems considering the sequence-dependent setup time in seru production system (SPS), which is a new-type manufacturing system originated in Japanese production practice recently that can better adapt to the fluctuate market demand. A mixed integer programming (MIP) model with the objective of minimizing the sum of the makespan and the weighted tardiness is constructed for the seru scheduling problem. The two-phase B&B (TPBB) algorithm is designed subsequently, where the first phase solves the assignment of products to serus , while the second phase solves the scheduling optimization in each seru . Finally, the computational experiments and comparative analysis with CPLEX 12.8 are made, and the report of results verifies that the effectiveness and practicability of the proposed MIP model and TPBB algorithm.
PENGARUH LOGO HALAL, KESADARAN HALAL, DAN SIKAP KONSUMEN UNTUK KEMBALI MEMBELI PRODUK MAKANAN DAN MINUMAN KEMASAN
Authors: Alinda Riska , Adinugraha Hendri Hermawan 
Published: November 2022

Abstrak: Kegiatan ekonomi tidak dapat dipisahkan dari pergantian peristiwa dan kemajuan produk. Selanjutnya, sebagai negara Muslim yang berpenduduk mayoritas Muslim, tentunya sangat penting untuk memperhatikan dan mengetahui konsep kehalalan suatu barang, terlebih dengan kemajuan mekanis yang dapat mendukung pembentukan produk baru. Metode penelitian ini adalah kuantitatif dengan menggunakan teknik non probability sampling. Pengujian hipotesis menggunakan analisis regresi linier berganda dengan populasi mahasiwa IAIN Pekalongan dan sampel 34 yaitu mahasiswa Fakultas FEBI. Instrumen dalam penelitian ini menggunakan studi pustaka, kuesioner dan lainnya. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh logo halal terhadap perilaku konsumen terhadap makanan dan minuman kemasan, mengetahui kesadaran dari konsumen terhadap kehalalan dan mengetahui keputusan yang akan dibeli konsumen terhadap produk yang akan dibeli maupun sudah di beli. Hasil dari penelitian ini adalah bahwa logo halal dan kesadaran halal berpengaruh signifikan terhadap keputusan minat beli ulang produk makanan dan minuman kemasan pada mahasiswa Fakultas FEBI Iain Pekalongan. Penelitian ini dapat digunakan sebagai bahan evaluasi bagi para konsumen yang ingin membeli suatu produk makanan dan minuman kemasan agar lebih memperhatikan label halal di kemasannya terutama bagi konsumen yang Muslim.
Kata Kunci: Logo halal, kesadaran hala, pengaruh logo halal, keputusan minat beli.

Abstract: Economic activity cannot be separated from the turn of events and the progress of products. Furthermore, as a Muslim country with a Muslim majority population, it is crucial to pay attention to and know the halalness of an item, especially with mechanical advances that can support the formation of new products. This research method is quantitative using a non-probability sampling technique. Hypothesis testing using multiple linear regression analysis with a population of IAIN Pekalongan students and a sample of 34 students from the Faculty of Economics and Business Islam (FEBI). Instruments in this study use literature studies, questionnaires, and others. This study aimed to determine the effect of the halal logo on consumer behavior towards packaged food and beverages, consumer awareness of halalness, and the decisions that consumers will buy on products to be purchased or already purchased. The results of this study are that the halal logo and halal awareness significantly affect the decision to repurchase packaged food and beverage products in FEBI students, Iain Pekalongan. This research can be used as an evaluation material for consumers who want to buy a packaged food and beverage product to pay more attention to the halal label on the packaging, especially for Muslim consumers.
Keywords: Halal logo, halal awareness, influence of halal logo, decision to buy interest
Matrix Metalloproteinases in Pathogenesis of Ventilation Disorders of the Respiratory System in Patients with Chronic Pulmonary Tuberculosis
Authors: Esmedlyaeva D. S. , Alekseeva N. P. , Kiryukhina L. D. , Dyakova M. E. 
Published: November 2022

The imbalance in matrix metalloproteinase (MMP)/inhibitors system leads to degradation of extracellular matrix of connective tissue and pathological remodeling forming the morphological basis for respiratory dysfunction.The objective: to study the relationship between parameters of MMP/inhibitors system in blood and parameters of ventilation and gas exchange disorders in patients with chronic pulmonary tuberculosis (PTB).Subjects and Methods. Patients with the verified diagnosis of tuberculoma (n = 45) and fibrous-cavernous pulmonary tuberculosis (n = 85) were examined. All patients underwent computed tomography of the chest and assessment of respiratory function. Serum concentrations of MMP-1, -3, -8, -9 and their inhibitors TIMP-1 and α2-macroglobulin (MG) were tested by ELISA (R&D Systems, Minneapolis, MN, USA). Statistica 7.0 and an ANCOVA model were used for statistical analysis which considered the diagnosis and smoking status as factors, and the respiratory function parameters were considered as covariates.Results. In pulmonary tuberculosis patients, the concentrations of MMP-9 and MMP-8 in the blood correlated with extension of lung parenchyma lesions when compared to tuberculomas and fibro-cavernous tuberculosis, MMP-9 and TIMP-1 with changes in lung volumes (R2 = 0.60 and 0.80; p = 0.001), and MMP-8 correlated with functional disorders of gas exchange (R2 = 0.60 and 0.80; p = 0.001). Changes in MMP-1, MMP-3, and α2-MG (R2 = 0.60 and 0.80; p = 0.45) did not correlate with extension of lung parenchymal lesions and decreased lung function.
Immune Disorders in Patients with Pulmonary Tuberculosis with Primary and Acquired Drug-Resistance of <i>Mycobacterium Tuberculosis</i>
Authors: Lesnik E. , Ginda S. 
Published: November 2022

The objective: to evaluate main parameters of cellular, humoral immunity and natural resistance in tuberculosis patients with primary and acquired multiple drug resistance; to study the correlation of these parameters with clinical and radiological manifestations.Subjects and Methods. A prospective study was conducted which included 169 patients with pulmonary tuberculosis, 80 of them were new cases of drug susceptible pulmonary tuberculosis and they made the Comparison Group (CG), and 89 patients suffered from multiple drug resistant tuberculosis and they made the Main Group (MG). The Main Group was divided into 2 subgroups: MG-1 – 40 patients with primary multiple drug resistant tuberculosis; MG-2 ‒ 49 patients who acquired drug resistance of Mycobacterium tuberculosis during treatment of tuberculosis.The immune assays included the lymphocyte blast transformation reaction (LBTR) to phytohemagglutinin and tuberculin (PPD), immunophenotyping of CD3+ and CD19+ cells; phagocytic index and phagocytic number were calculated; nitro blue tetrazolium test was used, concentrations of immunoglobulins and antimycobacterial antibodies were determined.Results. The clinical laboratory data demonstrated a more severe course of the disease in patients with multiple drug resistant tuberculosis, especially in those with acquired multiple drug resistant tuberculosis which was confirmed by the severity of immune deficiencies of the cellular immunity and innate resistance as well as by the overactivity of humoral immunity. The levels of CD3+ and LBTR reaction to PPD had a negative correlation with clinical manifestations and radiological features demonstrating the severity of pulmonary tuberculosis in patients with multiple drug resistance, especially in those with acquired multiple drug resistance; and CD19+ and antimycobacterial antibodies positively correlated with clinical manifestations and radiological signs.Conclusions. Parameters of cellular immunity and natural resistance were the lowest in the patients with acquired multiple drug resistance of Mycobacterium tuberculosis versus primary multiple drug resistance and drug susceptible Mycobacterium tuberculosis. Parameters of humoral immunity demonstrated the increased activity to compensate for the insufficiency of cellular immunity regardless of the type of resistance of Mycobacterium tuberculosis.
Acceptability of Telemedicine Among Parents of Adolescent Patients in an Adolescent Clinic: Cross-sectional Survey Study
Authors: Olateju Adetola , Cervantes Marbella , Dowshen Nadia , Kuhns Lisa M , Dhar Cherie Priya 
Published: November 2022

Background
Since the beginning of the COVID-19 pandemic, new literature has described the perceptions of adolescent patients on the use of telemedicine for their health care, but less attention has been devoted to parents’ and caregivers’ perspectives on telemedicine usage for their adolescents. Parents’ perspectives are important, as they undoubtedly influence how children learn to make decisions about their health care.

Objective
This study describes the level of acceptability (measured based on accessibility and satisfaction) expressed by caregivers of adolescent patients with regard to telemedicine visits in an urban adolescent medicine practice.

Methods
A cross-sectional survey was sent electronically to parents and guardians of patients aged <18 years who completed outpatient telemedicine visits to an adolescent medicine practice in Chicago, Illinois, from March 2020 to February 2021. The questions focused on accessibility and satisfaction. The data were analyzed to describe response frequencies.

Results
Among a sample of 71 survey respondents, the vast majority reported that telemedicine was very easy to use (58/71, 82%) and was at least as convenient as in-person visits (70/71, 99%). Over 90% of respondents reported that their adolescents’ needs were addressed (69/69, 100%) and that they were at least as comfortable with the level of privacy and the confidential conversations between their adolescents and medical providers in telemedicine visits (65/71, 92%) as they were with those in in-person visits.

Conclusions
Our findings suggest that parents and guardians find telemedicine to be an acceptable way for their children and adolescents to receive appropriate health care.