bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age-related osteogenesis on lateral force application to rat incisor – Part III: Periodontal and periosteal bone remodeling
Authors: Mo Sung-Seo , Kim Jin-Wook , Baik Hyoung-Seon , Giap Hai-Van , Lee Kee-Joon 
Published: January 2022

Objectives:
This study was aimed to compare the histological pattern of bone modeling on either periodontal or periosteal side induced by lateral orthodontic tooth movement in different age groups.

Material and Methods:
A total of 50 male Sprague-Dawley rats (25 rats in the adult group – 52 weeks and 25 rats in the young group – 10 weeks) were utilized in this study. Each age group was classified into the control, 3 days, 7 days, 14 days, and 21 days groups (five rats in each) by the duration of experimental device application. A double-helical spring was produced using 0.014” stainless steel wire to provide 40 g lateral force to the left and right incisors. Hematoxylin-eosin staining, proliferating cell nuclear antigen (PCNA) immunohistochemical staining, fibroblast growth factor receptor 2 (FGFR2) immunohistochemical staining, and Masson trichrome staining were performed; and the slides were subject to histological examination.

Results:
In 7 days, active bone modeling represented by the scalloped surface was observed on the periosteal side of the crestal and middle alveolus at the pressure side in the young group, while similar changes were observed only on the crestal area in the adult group. In the young group, the number of PCNA-positive cells increased significantly on the crestal area and middle alveolus on the 3, 7, and 14 day groups, with subsequent decrease at 21 days. In the adult group, PCNA-positive cells were localized on the crestal area throughout the period. In the young group, FGFR2-positive cells were observed mainly on the crestal and middle alveolus at 3, 7, and 14 days than the control group. In the adult group, these cells appeared on the crestal and middle alveolus in the 3 days group, but mainly on the crestal area at 14 days. In the young group, FGFR2-positive cells were observed on the crestal and middle alveolus on the 3, 7, and 14 days groups more than on the control group. In the adult group, these cells appeared on the crestal and middle alveolus in the 3 days group, but mainly on the crestal area in the 14 days group. In Masson trichrome stain, an increased number of type I collagen fibers were observed after helical spring activation in both age groups. Large resorption lacunae indicating undermining bone resorption were progressively present in both young and adult groups.

Conclusion:
According to these results, orthodontic tooth movement may stimulate cell proliferation and differentiation primarily on the periosteal side according to progressive undermining bone resorption on the periodontal side. This response may lead to prominent bone modeling during tooth movement in the young group, compared to the relatively delayed response in the adult group.
Assessment and homoeopathic management of psychological stresses and somatic illnesses in high school students from rural Palghar: Observational case series
Authors: Yadav Rajesh Ramkunwar , Patel Manoj Kanchanbhai 
Published: January 2022

Objectives:
Children are often taken to paediatricians for recurrent physical illnesses, which often cannot be diagnosed due to a lack of confirmed investigation findings. It is important to study various psychological stressors they might be undergoing to explain such somatic complaints. Understanding the types of somatic symptoms and nature of stressors in school-going children would also enable us to use Homoeopathy in managing these cases. This is all the more important in a rural set-up, where specialist consultation is difficult to obtain.

Material and Methods:
Six successfully treated children from three rural high schools in Palghar area with recurrent and different somatic illnesses were selected from a part of a larger population studied. These cases have been presented with an aim to study the clinical manifestations and underlying stressors. Management with Homoeopathic medicines along with the use of some stress management skills have been presented.

Results:
Various life situations such as change of school, staying away from parents or interaction patterns of family members were found to have a direct impact on the genesis of either anxiety or anger. As a result, children developed recurrent somatic illnesses, which in turn affected their academic performance. Homoeopathy, along with stress management skills, helped the children to overcome the psychological stresses and reduce the burden of somatic illnesses.

Conclusion:
The external environment is often the same for all students in schools, but a vulnerable few are affected. This results in the development of anxieties, specifically of strangers, of the future, of teachers, or of losing parents; this in turn causes insecurity.
Endovascular treatment of medium and large intracranial aneurysms with large volume coils: A single-center experience
Authors: Saal-Zapata Giancarlo , Ghodke Basavaraj , Walker Melanie , Pregúntegui-Loayza Ivethe , Rodríguez-Varela Rodolfo 
Published: January 2022

Background:Large volume coils are an alternative to conventional coils for the treatment of intracranial aneurysms. However, there are no published reports documenting occlusion and complication rates in medium and large intracranial aneurysms. Therefore, we present our results in this subgroup of aneurysms.Methods:A single-center, retrospective analysis of consecutive patients treated with Penumbra coils 400 in aneurysms ≥7 mm was performed. Demographics, aneurysm features, procedural details, intraoperative complications, clinical outcomes, and occlusion rates were analyzed.Results:Thirty-three patients were included for analysis, and a total of 33 intracranial aneurysms were analyzed. Mean age was 57.6 years (SD ± 12.4) and 85% of the patients were women. Large aneurysms represented 46% of cases. Paraclinoid (55%) followed by posterior communicating (30.3%) aneurysms was the most frequently treated. Ruptured and saccular aneurysms were found in 49% and 63% of the cases, respectively. The mean aneurysmal dimensions were 14.2 mm width, 11.9 mm length, 5.4 mm neck, and 2.4 dome-to-neck ratio. A dome-neck ratio <2 was identified in 39% of cases. The mean number of coils per aneurysm was 4.8. Immediate modified Raymond–Roy Grades 1, 2, and 3A were achieved in 15%, 21%, and 64%, respectively. Twenty-six patients were evaluated at a mean follow-up period of 11 months, with an adequate occlusion of 92% and a good clinical outcome (modified Rankin score ≤2) in 96% of patients.Conclusion:Endovascular treatment with PC400 coils is an effective and safe option for medium and large intracranial aneurysms with high occlusion rates, few complications, and good clinical outcomes at follow-up.
INFLUENCE OF NANODISPERSED METAL POWDERS ON THE COMBUSTION OF ENERGY CONDENSED SYSTEMS BASED ON AMMONIUM NITRATE WITH DIFFERENT TYPE OF POLYMER BINDER
Authors: Попов В.О. , Комов В.Н. , Попенко Е.М. , Сергиенко А.В. 
Published: January 2022

Определены особенности горения энергетических композиций на основе инертного и активного горючих-связующих с нитратом аммония в диапазоне давлений до 10 Мпа. Представлен сравнительный анализ влияния наноразмерных порошков металлов на процесс горения композиций с различными наполнителями: октоген, нитрат аммония, CL-20. Показана эффективность нанопорошков металлов (Cu, Ni, Mo, Al, Zn) и неметалла (B) в качестве катализаторов горения.
The features of combustion of energy compositions based on inert and active combustible binders with ammonium nitrate in the pressure range up to 10 MPa have been determined. A comparative analysis of the effect of nanosized metal powders on the combustion process of compositions with various fillers: HMX, ammonium nitrate, CL-20 is presented. The efficiency of metal (Cu, Ni, Mo, Al, Zn) and non-metal (B) nano powders as combustion catalysts is shown.
NUCLEOPHILIC SUBSTITUTION OF NITRO GROUP IN 1-METHYL- 5-NITRO-1,2,4-TRIAZOLE BY DIAMINOGLYOXIME
Authors: Крупнова И.А. , Суханов Г.Т. , Босов К.К. , Суханова А.Г. , Филиппова Ю.В. , Пивоварова Е.В. , Чикина М.В. 
Published: January 2022

Изучен процесс взаимодействия 1-метил-5-нитро-1,2,4-триазола с многоцентровым бифункциональным О-нуклеофилом – диаминоглиоксимом. Показано, что исходный субстрат вступает в реакцию SNipso-замещения нитрогруппы с гидроксильными группами О-нуклеофила с образованием биологически активного соединения, объединяющего в единой молекуле фармакофорные фрагменты различного типа – 1,2,4-триазоловые гетероциклы и NH2-группы. Процесс сопровождается конкурентными реакциями образования триазолона и продукта его дальнейшего взаимодействия с исходным субстратом. С помощью веб-ресурса PASS Online осуществлен компьютерный скрининг, показано, что исходный субстрат и продукты реакции могут выступать потенциальными фармацевтическими субстанциями.
The reaction between 1-methyl-5-nitro-1,2,4-triazome and a concerted bifunctional О-nucleophile – diaminoglyoxime was explored herein. The starting substrate was shown to engage into the SNipso-substitution of the nitro group by the О-nucleophile hydroxyls to furnish a bioactive compound whose single molecule combines different-type pharmacophoric moieties – 1,2,4-triazole heterocycles and NH2groups. The process came amid competitive reactions to form triazolone and a product from its subsequent reaction with the starting substrate. The PASS Online web-resource was used to perform computer-aided screening, demonstrating that the starting substrate and the reaction products can serve as potential pharmaceutical substances.
VENICE AND DOLO IN THE MODERN TOWN PLANNING OF RIVIERA DEL BRENTA SYSTEM: ARCHITECTURAL, LIGHT AND CULTURAL ENVIRONMENT, LANDMARKS AND DOMINANTS
Authors: Карпенко Владимир Евгеньевич , Касьянов Николай Владимирович , Волчок Юрий Павлович 
Published: January 2022

В статье анализируется архитектурная среда Венеции и Доло с точки зрения взаимодействия ориентиров, доминант, перспектив цифровой и психологической навигации. Современное использование исторических объектов Венеции и Доло для проведения различных торжеств и культурных событий на фоне подлинных интерьеров и архитектуры, насыщенных различными символами и произведениями искусства, создает условия дальнейшего функционирования их общественной жизни и туристической привлекательности. Анализируется архитектурно-световая среда жилых районов и центральной части Доло. Рассматриваются история и архитектура некоторых сооружений Венеции и вилл Бренты как исторических доминант и ориентиров в градостроительной структуре. Проведение выставок, инсталляций и воркшопов в исторических и современных пространствах Доло способствует формированию комфортной, безопасной среды и созданию позитивной эмоциональной атмосферы города.
The architectural environment of Venice and Dolo from the point of view of the interaction of landmarks, dominants, perspectives of digital and psychological navigation are analyzed in the article. The modern use of the historical sites of Venice and Dolo for various celebrations and cultural events on the backdrop of authentic interiors and architecture, saturated the various symbols and works of art, creates conditions for the further functioning of their social life and tourist attractiveness. The architectural and light environment of residential areas and the central part of Dolo is analyzed. The history and architecture of some of the buildings of Venice and Brenta’s villas as historical dominates and landmarks in the urban planning structure are considered. Holding exhibitions of installations and workshops in historical and modern spaces Dolo contributes to the formation of comfortable, safe environment and the creation of a positive emotional atmosphere of the city.
SOCIO-SPATIAL TRANSFORMATION OF OPEN PUBLIC SPACES OF RESIDENTIAL AREAS UNDER THE INFLUENCE OF DYNAMIC PROCESSES OF LIVING
Authors: Чуй Яна Владимировна , Кукина Ирина Валериевна , Бондаренко Игорь Андреевич 
Published: January 2022

Сегодня, в ответ на процессы глобализации, международной миграции, социальной сегрегации и неравномерного развития периферийных районов города, переосмысливается значение общественных пространств в жилой среде. Общественные пространства выступают в качестве инструмента экономического и социального укрепления периферийных жилых районов. Их характер и пространственная структура определяются социально-экономическими и социально-культурными процессами развития территории. Анализ мирового опыта модернизации существующих и создания новых общественных пространств жилой среды позволяет выделить их морфологические типы, сложившиеся под влиянием динамических процессов жизнедеятельности.
Today, in response to the processes of globalization, international migration, social segregation, and unequal development of a city’s peripheral areas, the value of public places in residential environment is being redefined. Public spaces are increasingly as a tool for economic and social revival of peripheral areas. Their nature and spatial structure is determined by the socio-economic and socio-cultural processes of developing the territories. Analysis of the world experience in the modernization of existing and creation of new public spaces of residential areas can be highlighted their morphological types, formed under the influence of dynamic processes of living.
PARK «ZARYADIE» AS A NEW ARCHITECTURAL AND LANDSCAPE REALITY IN MOSCOW
Authors: Касьянов Николай Владимирович , Казарян Армен Юрьевич , Волчок Юрий Павлович 
Published: January 2022

В статье рассказывается об архитектурно-ландшафтном эксперименте в историческом центре Москвы. Район Зарядье, упоминаемый с XII века, имеет богатую историю; динамичные изменения здесь происходили в XX веке, когда историческая застройка была снесена и на этой территории последовательно пытались реализовать несколько крупномасштабных архитектурных проектов. В итоге к 2010-м годам территория превратилась в пустырь в центре города. К сентябрю 2017 года на этом месте был создан архитектурно-ландшафтный парк по проекту победившей в конкурсе американской фирмы «Diller Scofidio + Renfro». В парке реализован искусственный рельеф, в который интегрированы здания различного культурного назначения. Парк уже отмечен рядом международных наград.
The article describes the architectural landscape experiment in the historical center of Moscow. The district Zaryadie mentioned from the 12th century, has a rich history. Dynamic changes took place here in the 20th century, when the historical buildings were demolished and several large-scale architectural projects were been attempted to implement on this territory. As a result, by 2010 the territory turned into a wasteland in the center of the city. By September 2017, an architectural and landscape park was created at the site according to the project of the American company Diller Scofidio + Renfro that won the competition. The park has an artificial relief in which buildings of various cultural purposes are integrated. The park has already bestowed several international awards.
ENVIRONMENTAL PERFORMANCE AS A DRIVE TO GENERATE DESIGN OPTIONS... IN EARLY URBAN DESIGN STAGE: A PARAMETRIC MODEL DEVELOPMENT FRAMEWORK
Authors: Леунг Джерри , Кэмпбэлл Кристофер , Садовски Лукаш Миколай 
Published: January 2022

Предыдущие исследования показали, что для решения задач в области градостроительного проектирования возможно применение параметрического моделирования. Были также предприняты попытки включить в градостроительные параметрические модели экологическую эффективность. Однако в этих исследованиях экологическая эффективность присутствовала только в качестве результата параметрического моделирования. Возможность использования экологической эффективности в качестве вводных данных до сих пор не рассматривалась. Таким образом, главная цель настоящего исследования заключается в том, чтобы найти подход к построению модели, который позволил бы использовать экологическую эффективность в качестве вводных данных в градостроительном параметрическом моделировании. Для демонстрации возможностей практического применения такого подхода предлагается построение параметрической модели озелененного общественного пространства.
Previous studies have demonstrated that it is possible to utilize parametric model for urban design tasks. There were also attempts to include environmental performances in parametric urban design models. However, environmental performances were only treated as outputs of parametric models in these studies. The feasibility of treating the performances as inputs has not been revealed yet. As a result, the primary objective of this study is to develop a model development framework which can aid the development of parametric urban design models embracing environmental performances as inputs. The development of a parametric model for green open space design was utilized as a case study to demonstrate how this framework can be applied.
GOLGOTHA AND THE TOMB OF THE LORD BEFORE THE BUILDING OF THE CHURCH OF THE HOLY SEPULCHRE: UNDERSTANDING OF THE PROBLEM, HYPOTHESES AND RECONSTRUCTIONS
Authors: Лаврентьева Елена Сергеевна 
Published: January 2022

Храм Гроба Господня составляет единый комплекс с прилегающими к нему постройками, являющимися своеобразным продолжением и оградой святыни. Он расположен на сравнительно небольшом участке и, несмотря на это, включает в себя значительный комплекс разновременных строений. Это и греческие монастыри Святогробского Братства, св. Харалампия, Авраама, Гефсиманское подворье, и монастырь францисканцев, коптский монастырь св. Антония, эфиопский монастырь Дейр аль-Султан и др.Главными в историографии по-прежнему остаются вопросы достоверности места расположения Храма Гроба Господня и предшествовавшего ему античного храма, возведенного римлянами с целью скрыть место духовного поклонения христиан. Исследование проблем затрудняют временнáя отдаленность событий, неоднородность, противоречивость и сложность источников, а также бытующие в литературе буквально воспринятые мифы и легенды.Сложный рельеф местности оказал несомненное влияние на архитектурный облик комплекса, складывавшегося на протяжении длительного времени. Реконструкции местности довольно разнообразны и противоречивы. Дополнительные археологические раскопки в основании Храма выявили бы недостающие элементы для восстановления архитектурной истории памятника. В статье анализируются исторические и археологические сведения, а также научные предположения и реконструкции, посвященные специфике рельефа местности и особенностям фундаментов построек, располагавшихся на данной территории до возведения Храма Воскресения Христова.
The Church of the Holy Sepulchre and the monastery buildings adjacent to it is a huge unified complex. It is located on a relatively small area, and, despite this, includes a significant complex of structures from different periods. These are the Greek monasteries of the Brotherhood of the Holy Sepulchre, St. Charalambos, Abraham, Gethsemane Compound, and the Franciscan monastery, the Coptic monastery of St. Anthony, the Ethiopian monastery of Deir Al-Sultan, etc. Unresolved issues remain in historiography: the issues of the reliability of the location of the Church of the Sepulcher and the existence of the roman temple. The investigation of the problems are obstructed by temporary distant events, heterogeneity, inconsistency and complexity of sources study base, as well as literally perceived myths and legends. The irregular terrain of the ground influenced the architectural appearance of the complex. Reconstruction of the area is quite diverse and contradictory. Additional archaeological excavations at this area might reveal missing elements to restore the architectural history of the monument. Analyzed and systematized in this article is historical and archaeological information, as well as scientific assumptions and reconstructions, devoted to the study of the features of the terrain and the foundations of buildings located on this territory before the building of the Church of the Holy Sepulchre.
THE DEVELOPMENT OF THE WESTERN FAÇADE IN THE LATE FRENCH GOTHIC
Authors: Позднякова Марина Игоревна 
Published: January 2022

В данной статье типология фасадов с портиками рассматривается как заключительный этап развития готического фасада. В конце XV в. фасады с портиками появляются в памятниках, программных для этого периода. На примере фасадов церквей Сен-Маклу в Руане, Нотр-Дам в Алансоне и Сен-Жермен в Аржантане показано, что введение портика в композицию фасада позволяет создать невозможные ранее пространственные и светотеневые эффекты, столь важные для поздней готики. Но анализ построения архитектурной формы приводит к неожиданным выводам. Ценность фасадов с портиком определяется не их инновационным характером, но изменением прежних принципов организации двухбашенного фасада, а их появление обусловлено не только стилистическими особенностями поздней готики, но и тенденциями, которые определяли развитие фасада еще с XII в. Именно это и позволяет встроить фасады с портиками в общую эволюцию готического фасада.
This article examines porches of western facades as the final stage in the development of the Gothic facade. At the end of the 15th century, porches appear in the main churches of this period (Saint-Maclou at Rouen, Notre-Dame at Alençon, Saint-Germain at Argentan). Introduction of the porch into façade composition allows for the creation of spatial effects and contrast of light and shadow, so important for Late Gothic. But the analysis of architectural form construction leads to unexpected conclusions. The significance of facades with porches is determined not only by their innovative nature, but by the change of the previous principles of organization of the two-tower façade. Their appearance is due not only to stylistic features of late Gothic, but also to trends that determined the development of the facade since the 12th century. It seems therefore evident, that the porches are a stage of evolution of the Gothic facade.
UNWANTED ANNIVERSARIES
Authors: Волчок Ю.П. 
Published: January 2022

Начиная с 2018 года наступил период, насыщенный интересующими архитектурное сообщество юбилеями. При фиксации вековой, как правило, даты они отличаются разной мерой погружения в предмет, что зависит во многом от современной нам интерпретации значимости каждого из юбилейных событий для понимания устройства целого в архитектуре и градостроении. В статье предпринята попытка в юбилейном контексте выявить многогранные истоки сложения, отвечающего нашему времени понимания объемно-пространственного устройства города в отечественной версии диалога культуры и цивилизации.
2018 has witnessed the commencement of the period full of anniversaries interesting, among others, to the architectural community. The dates usually fix a centennial, but differ in various extent of involvement with the subject, due to the contemporary interpretations of significance of respective events subject to centennial celebrations, for comprehension of the structure of the whole in architecture and urban planning. This article is an attempt to identify in the context of such anniversaries the roots of gradual formation over the course of time of the present-day perception of urban spacial arrangement in the Russian version of the dialogue between the culture and the civilization.