bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of pre-sintering and high-temperature infiltration on the properties of single-domain YBCO bulk superconductors by the Y + 011 top-seeded infiltration growth process
Authors: Abulaiti Abulizi , Yang Wan-Min , Wu Ting-Ting , Cui Yan-Lan 
Published: December 2022

Abstract
The top-seeded infiltration growth process (TSIG) is one of the most important methods for the fabrication of single-domain rare-earth barium copper oxide (REBCO) bulk superconductors. The performance of samples is in the main closely related to the quality of the solid phase pellets (SPPs). In this paper, we report a new method for optimizing the SPPs and properties of single-domain REBCO bulks, including sintering of the SPPs (Y2O3 + BaCuO2), infiltration of the Ba–Cu–O liquid phase and the melting growth process. A group of single-domain YBCO bulk superconductors with a diameter of 20 mm have been fabricated by the modified RE + 011 TSIG method. Both the levitation force and the trapped field of the samples increase at first and then decrease with increase in the sintering time. The largest levitation force of 42.8 N and trapped field of 0.41 T (77 K, 0.5 T) are obtained in the sample sintered at 1000 °C for 4.5 h; this is mainly related to the optimal microstructure of the pre-sintered SPPs and the YBCO bulk. These results indicate that pre-sintering and high-temperature infiltration is a very important method for controlling the microstructure and improving the physical properties of single-domain YBCO bulk superconductors.
Analysis and design of overmoded coaxial Ku-band Cerenkov high power microwave oscillator with high efficiency
Authors: Yang Chaochao , Meng Jin , Deng Bingfang , Wang Haitao 
Published: December 2022

Abstract
An overmoded coaxial Ku-band Cerenkov high power microwave oscillator with high efficiency is proposed. The distance between the inner and outer conductors of the slow wave structure (SWS) in the Cerenkov oscillator is smaller than the space wavelength of output microwave. The overmoded structure can increase the power capacity of the oscillator by increasing the transversal size of the device. The higher-order modes are introduced into the beam-wave interaction region intentionally, so that the intense relativistic electron beams (IREB) interacts with the fundamental and higher-order modes. Dual-mode operation leads impure mode component to output microwave, so the simple trapezoid inner conductor is designed to achieve mode purification and output pure TEM mode. The extractor is added at the end of the SWS, which enhances the axial electric field near the location and increases the modulation depth of the electron beam current passing through the region. The particle-in-cell (PIC) simulation results show that under the input power of 3.5 GW, the output microwave power is 1.8 GW, and the corresponding working efficiency is 51.4%, which is much higher than that of similar periodic devices. The mode of output microwave is pure TEM mode, and the maximum surface electric field intensity is 0.96 MV cm−1, which means that the probability of radio-frequency breakdown is low.
Relativistic thermodynamics on conveyor belt
Authors: Güémez J , Mier J A 
Published: December 2022

Abstract
Two thermodynamic processes are analysed by using a relativistic four-vector fundamental equation formalism: the launching of a projectile by forces produced by chemical reactions inside a cannon (equivalent to a person launching a ball) placed on a moving platform, a mechanical energy production process, and the Joule-Kelvin process implemented on a conveyor belt. Each process is first studied in frame S, in which the device—the cannon or the porous plug –, is at rest, obtaining its four-vector fundamental equation dE

μ
= δ
W

μ
+ δ
Q

μ
. Using the Lorentz transformation, the corresponding four-vector equation in frame

S

¯

—in which the processes are carried out on a moving platform or a conveyor belt—

d

E

¯

μ

=
δ

W

¯

μ

+
δ

Q

¯

μ

, is obtained, obeying Einstein’s principle of relativity. For the relativistic description to be coherent, one has to assign linear momentum to the non-mechanical energies and consider their variations in the corresponding Newton’s second law equation and the relativistic non-simultaneity and conveyor belt effects. In relativistic thermodynamics, Newton’s second law and the first law of thermodynamics are not independent equations. It is shown that entropy variations and fuel consumption are frame independent magnitudes.
Theoretical and computational study of a partially coherent laser beam in a marine environment
Authors: Chib Salma , Bayraktar Mert , Belafhal Abdelmajid 
Published: December 2022

Abstract
The propagation formula of a partially coherent Generalized Flattened Hermite-Cosh-Gaussian (GFHChG) beam in maritime atmospheric turbulence is derived with the help of the extended Huygens–Fresnel principle. In addition, the analytical expression for the beam width of a partially coherent GFHChG beam in the considered environment is investigated. From the numerical results based on the analytical formulae, we find that the analyzed beam can take different shapes of the profile, depending on the turbulence and beam parameters. And also, it can significantly resist turbulence with small wavelength and waist width values. On the other hand, when the medium becomes turbulent, the beam loses its characteristics and its resistance to fluctuations. Furthermore, the results reveal that the beam spreads more rapidly with the increase of the strength of turbulence, the outer scale size, and the decrease of the inner scale size. We should mention that the results gained represent a general form of numerous partially coherent laser beams such as Generalized Flattened Hermite Gaussian, Generalized Flattened Cosh-Gaussian, Hermite-Cosh-Gaussian, Cosh-Gaussian, Hermite-Gaussian and Gaussian Schell model beams.
Uncertainty relations for coherence quantifiers based on the Tsallis relative 1/2-entropies
Authors: Rastegin Alexey E 
Published: December 2022

Abstract
In quantum information science, systems with incomplete information are typically dealt with. To characterize quantumness from different viewpoints, several kinds of non-classical correlations should be described quantitatively. The concept of coherence within purely quantum framework is currently the subject of active research. A certain attention is paid to coherence quantifiers averaged with respect to a set of quantum ensembles or special measurements. Mutually unbiased bases and symmetric informationally complete measurements are important examples. We present uncertainty relations for quantum-coherence quantifiers based on the Tsallis relative 1/2-entropies. Together with mutually unbiased bases, the paper also deals with a measurement built of the states of an equiangular tight frame. The derived inequalities are exemplified with mutually unbiased bases and symmetric informationally complete measurement in two dimensions.
Energy property and covalency of H2S···X (X = N2, CO, CS and SiO) hydrogen bond
Authors: Xinying Li 
Published: December 2022

Abstract
CCSD(T) calculations on H2S…X (X = N2, CO, CS and SiO) series provide reliable structures, energy properties and covalency of hydrogen bonds (HB). Symmetry adapted perturbation theory analysis demonstrates the dominant role of electrostatic interactions for the relative stronger HBs; and the dispersion demonstrates the attraction of the very weak HB of H2S…N2. Upon formation of HBs, the electrostatic and dispersion energies play important role. The covalent character is analyzed by AIM theory and topological analysis on electron density functions; and it suggests the very weak strength of HBs with non-covalent character.
Power-law Distribution and Scale-invariant Structure from the First CHIME/FRB Fast Radio Burst Catalog
Authors: Wang Zi-Han , Sang Yu , Zhang Xue 
Published: December 2022

Abstract
We study the statistical property of fast radio bursts (FRBs) based on a selected sample of 190 one-off FRBs in the first CHIME/FRB catalog. Three power law models are used in the analysis, and we find the cumulative distribution functions of energy can be well fitted by bent power law and thresholded power law models. The distribution functions of fluctuations of energy well follow the Tsallis q-Gaussian distribution. The q values in the Tsallis q-Gaussian distribution are constant with small fluctuations for different temporal scale intervals, indicating a scale-invariant structure of the bursts. The earthquakes and soft gamma repeaters show similar properties, which are consistent with the predictions of self-organized criticality systems.
The second version of InRaDoS, a free computer program for internal dosimetry
Authors: Sadre Momtaz Alireza , Safarnejad Farzin 
Published: December 2022

Abstract
The calculation of absorbed and effective doses due to the administration of radiopharmaceuticals needs physical data such as radionuclide's half-life and nuclear decay data. Also, it needs the data on the biodistribution of the radiopharmaceutical in the body. This process is time-consuming, and there is a possibility of human error in the calculations. Therefore, computer programs were developed to facilitate and speed up the dose calculation. The purpose of this paper is to report the steps taken for the development of the second version of InRaDoS. InRaDoS 2 is a free computer program for internal dosimetry. This program was developed using the tkinter module of Python programming language. The dose calculations were based on the MIRD method and only for adults. The user can calculate the doses for revised ORNL or ICRP adult reference phantoms.
For now, 98 and 29 radiopharmaceuticals (138 and 42 biokinetic models) are available for the revised ORNL and ICRP adult reference phantoms, respectively. The results of the InRaDoS 2 show good agreement with the published data and free available software. InRaDoS 2 is freely available for download on GitHub
(https://github.com/farzinsafarnejad/InRaDoS-2).
Rapid expansion of irrigated agriculture in the Senegal River Valley following the 2008 food price crisis
Authors: Higginbottom Thomas P , Adhikari Roshan , Foster Timothy 
Published: December 2022

Abstract
The expansion of irrigated croplands throughout the 20th century boosted global agricultural productivity, yet limited improvement occurred in sub-Saharan Africa where many irrigation schemes and policies under-delivered. We mapped the distribution of croplands under active irrigation between 1986 and 2020 for one of Africa’s largest and most important transboundary river basins—the Senegal River Valley; using Landsat imagery with a random forest classifier and hidden Markov Model. We document two distinct epochs of irrigation development. Initially, a period of stagnation where less than 900 ha yr−1 was added, lasting until 2008. Followed by a boom phase of rapidly expanding intensively irrigated production with ∼9,000 ha yr−1 added for the last 12 years. These epochs overlap with national agricultural policy frameworks: the 1980s laissez-faire policies limited state involvement in agriculture and promoted Asian imports; followed by a more interventionist period focused on promoting domestic production following the food price crisis of 2008.
Local mode analysis of characteristic vibrational coupling in nucleobases and Watson–Crick base pairs of DNA
Authors: Quintano Mateus , Delgado Alexis A A , Moura Jr Renaldo T , Freindorf Marek , Kraka Elfi 
Published: December 2022

AbstractTwo-dimensional infrared spectroscopy has reported highly delocalized in-plane base vibrations in the fingerprint region of nucleotide monophosphates, suggesting the involvement of base pair C=O and C=C ring bonds and considerable interaction between C=O bond stretches. The high delocalization results in congested vibrational spectra, which complicates the assignment of the peaks. This congestion also extends to Watson–Crick base pairs. We applied in this work the characterization of normal mode procedure, a special feature of our local mode analysis, and could for the first time identify the C=O and C=C bonds being engaged in base pair coupling and quantify their contribution to each of the delocalized fingerprint vibration. In addition, a detailed and quantitative description of the hydrogen bonds involved in the Watson–Crick base pairs was provided. Based on the results of this study, we developed a new protocol to elucidate on the assignment of bands in the vibrational spectra of nucleic acids by probing the vibrational space for specific interactions between functional groups prior to and upon base pairing. This protocol will aid to fill the gap between deoxyribonucleic acid structural information and vibrational spectroscopy experiments by facilitating the interpretation of spectra on a quantitative basis.
Computational prediction and characterization of cell-type-specific and shared binding sites
Authors: Zhang Qinhu , Teng Pengrui , Wang Siguo , He Ying , Cui Zhen , Guo Zhenghao , Liu Yixin , Yuan Changan , Liu Qi , Huang De-Shuang 
Published: December 2022

Abstract

Motivation
Cell-type-specific gene expression is maintained in large part by transcription factors (TFs) selectively binding to distinct sets of sites in different cell types. Recent research works have provided evidence that such cell-type-specific binding is determined by TF’s intrinsic sequence preferences, cooperative interactions with co-factors, cell-type-specific chromatin landscapes and 3D chromatin interactions. However, computational prediction and characterization of cell-type-specific and shared binding sites is rarely studied.

Results
In this article, we propose two computational approaches for predicting and characterizing cell-type-specific and shared binding sites by integrating multiple types of features, in which one is based on XGBoost and another is based on convolutional neural network (CNN). To validate the performance of our proposed approaches, ChIP-seq datasets of 10 binding factors were collected from the GM12878 (lymphoblastoid) and K562 (erythroleukemic) human hematopoietic cell lines, each of which was further categorized into cell-type-specific (GM12878- and K562-specific) and shared binding sites. Then, multiple types of features for these binding sites were integrated to train the XGBoost- and CNN-based models. Experimental results show that our proposed approaches significantly outperform other competing methods on three classification tasks. Moreover, we identified independent feature contributions for cell-type-specific and shared sites through SHAP values and explored the ability of the CNN-based model to predict cell-type-specific and shared binding sites by excluding or including DNase signals. Furthermore, we investigated the generalization ability of our proposed approaches to different binding factors in the same cellular environment.

Availability and implementation
The source code is available at: https://github.com/turningpoint1988/CSSBS.

Supplementary information
Supplementary data are available at Bioinformatics online.
Randomized double-blind placebo-controlled crossover trial with pyridostigmine in spinal muscular atrophy types 2–4
Authors: Stam Marloes , Wijngaarde Camiel A , Bartels Bart , Asselman Fay-Lynn , Otto Louise A M , Habets Laura E , van Eijk Ruben P A , Middelkoop Bas M , Goedee H Stephan , de Groot Janke F , Roes Kit C B , Schoenmakers Marja A G C , Nieuwenhuis Edward E S , Cuppen Inge , van den Berg Leonard H , Wadman Renske I , van der Pol W Ludo 
Published: December 2022

AbstractHereditary proximal spinal muscular atrophy causes weakness and increased fatigability of repetitive motor functions. The neuromuscular junction is anatomically and functionally abnormal in patients with spinal muscular atrophy. Pharmacological improvement of neuromuscular transmission may therefore represent a promising additional treatment strategy. We conducted a Phase II, monocentre, placebo-controlled, double-blind, cross-over trial with the acetylcholinesterase inhibitor pyridostigmine in treatment-naïve patients with spinal muscular atrophy types 2–4. We investigated the safety and efficacy of pyridostigmine on fatigability and motor function. Each participant received pyridostigmine and a placebo for 8 weeks, in random order. Primary outcomes were the repeated nine-hole peg test for fatigability and motor function measure. Secondary outcomes were patient-reported effects, endurance shuttle test combined scores and adverse events. We included 35 patients. For the repeated nine-hole peg test, the mean difference was 0.17 s/trial (95% confidence interval: −1.17–1.49; P = 0.8), favouring placebo, and for the motor function measure, 0.74% (95% confidence interval: 0.00–1.49; P = 0.05), favouring pyridostigmine. Around 74% of patients reported medium-to-large beneficial effects of pyridostigmine on fatigability, compared with 29.7% in the placebo arm. This was paralleled by a reduced dropout risk of 70% on the endurance shuttle test combined scores (hazard ratio: 0.30; 95% confidence interval: 0.15–0.58) under pyridostigmine. Adverse events, mostly mild and self-limiting, occurred more frequently under pyridostigmine. No serious adverse events related to the study medication were observed. Patients with spinal muscular atrophy tolerated pyridostigmine well. There were no significant differences in primary outcomes, but the self-reported reduction of fatigability and improved endurance shuttle test combined score performance suggest that pyridostigmine may be useful as an additional therapy to survival motor neuron-augmenting drugs.Trial registration number: EudraCT: 2011–004369-34, NCT02941328
fastball: a fast algorithm to randomly sample bipartite graphs with fixed degree sequences
Authors: Godard Karl , Neal Zachary P 
Published: December 2022

Abstract
Many applications require randomly sampling bipartite graphs with fixed degrees or randomly sampling incidence matrices with fixed row and column sums. Although several sampling algorithms exist, the ‘curveball’ algorithm is the most efficient with an asymptotic time complexity of $O(n~log~n)$ and has been proven to sample uniformly at random. In this article, we introduce the ‘fastball’ algorithm, which adopts a similar approach but has an asymptotic time complexity of $O(n)$. We show that a C$\texttt{++}$ implementation of fastball randomly samples large bipartite graphs with fixed degrees faster than curveball, and illustrate the value of this faster algorithm in the context of the fixed degree sequence model for backbone extraction.
Regulation at Drosophila’s Malic Enzyme highlights the complexity of transvection and its sensitivity to genetic background
Authors: Rzezniczak Teresa Z , Rzezniczak Mark T , Reed Bruce H , Dworkin Ian , Merritt Thomas J S 
Published: December 2022

Abstract
Transvection, a type of trans-regulation of gene expression in which regulatory elements on one chromosome influence elements on a paired homologous chromosome, is itself a complex biological phenotype subject to modification by genetic background effects. However, relatively few studies have explored how transvection is affected by distal genetic variation, perhaps because it is strongly influenced by local regulatory elements and chromosomal architecture. With the emergence of the “hub” model of transvection and a series of studies showing variation in transvection effects, it is becoming clear that genetic background plays an important role in how transvection influences gene transcription. We explored the effects of genetic background on transvection by performing two independent genome wide association studies (GWASs) using the Drosophila genetic reference panel (DGRP) and a suite of Malic enzyme (Men) excision alleles. We found substantial variation in the amount of transvection in the 149 DGRP lines used, with broad-sense heritability of 0.89 and 0.84, depending on the excision allele used. The specific genetic variation identified was dependent on the excision allele used, highlighting the complex genetic interactions influencing transvection. We focussed primarily on genes identified as significant using a relaxed P-value cutoff in both GWASs. The most strongly associated genetic variant mapped to an intergenic single nucleotide polymorphism (SNP), located upstream of Tiggrin (Tig), a gene that codes for an extracellular matrix protein. Variants in other genes, such transcription factors (CG7368 and Sima), RNA binding proteins (CG10418, Rbp6, and Rig), enzymes (AdamTS-A, CG9743, and Pgant8), proteins influencing cell cycle progression (Dally and Eip63E) and signaling proteins (Atg-1, Axo, Egfr, and Path) also associated with transvection in Men. Although not intuitively obvious how many of these genes may influence transvection, some have been previously identified as promoting or antagonizing somatic homolog pairing. These results identify several candidate genes to further explore in the understanding of transvection in Men and in other genes regulated by transvection. Overall, these findings highlight the complexity of the interactions involved in gene regulation, even in phenotypes, such as transvection, that were traditionally considered to be primarily influenced by local genetic variation.
Variations of stomata development in tea plant (Camellia sinensis) leaves in different light and temperature environments and genetic backgrounds
Authors: Li Ping , Lin Junming , Zhu Mingzhi , Zuo Hao , Shen Yihua , Li Juan , Wang Kunbo , Li Penghui , Tang Qian , Liu Zhonghua , Zhao Jian 
Published: December 2022

Abstract
Stomata perform important functions in plant photosynthesis, respiration, gas exchange, and interactions with environments. However, tea plant stomata development and functions are not known. Here, we show morphological changes during stomata development and genetic dissection of stomata lineage genes regulating stomata formation in tea developing leaves. Different tea plant cultivars displayed clear variations in the stomata development rate, density and size, which are closely related to their tolerance against dehydration capabilities. Whole sets of stomata lineage genes were identified to display predicted functions in regulating stomatal development and formation. The stomata development and lineage genes were tightly regulated by light intensities and high or low temperature stresses, which affected stomata density and function. Furthermore, lower stomatal density and larger size were observed in triploid tea varieties as compared to those in diploid plant. Key stomata lineage genes such as CsSPCHs, CsSCRM, and CsFAMA showed much lower expression levels, whereas negative regulators CsEPF1 and CsYODAs had higher expression levels in triploid than in diploid tea varieties. Our study provides new insight into tea plant stomatal morphological development and the genetic regulatory mechanisms on stomata development under abiotic stresses and genetic backgrounds. The study lays a foundation for future exploring of the genetic improvement of water use efficiency in tea plants for living up to the challenge of global climate change.
Teaching/Learning through “Black Earth Rising”: Poststructural, Decolonial, and Feminist Readings
Authors: Cuadro Mariela 
Published: December 2022

Abstract
The paper aims at reflecting on ways of teaching/learning international relations (IR) critical theories. It does so by analyzing the results of a teaching/learning exercise based on Netflix's series “Black Earth Rising” and put into practice with undergraduate students of a course on IR theory taught at the Argentinian Universidad Nacional de San Martín. Assuming that series of mass consumption work as cultural devices that inform power relations through the production of truths and subjectivities, the exercise had two main objectives: on the one hand, to develop and illustrate otherwise difficult-to-grasp concepts of IR theory and, on the other hand, to make the students aware of how widespread TV series participate in the constitution of both international politics and their own subjectivities.