bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seychelles warblers with silver spoons: Juvenile body mass is a lifelong predictor of annual survival, but not annual reproduction or senescence
Authors: Brown Thomas J. , Dugdale Hannah L. , Hammers Martijn , Komdeur Jan , Richardson David S. 
Published: July 2022

AbstractThe environment experienced during development, and its impact on intrinsic condition, can have lasting outcomes for individual phenotypes and could contribute to variation in adult senescence trajectories. However, the nature of this relationship in wild populations remains uncertain, owing to the difficulties in summarizing natal conditions and in long‐term monitoring of individuals from free‐roaming long‐lived species. Utilizing a closely monitored, closed population of Seychelles warblers (Acrocephalus sechellensis), we determine whether juvenile body mass is associated with natal socioenvironmental factors, specific genetic traits linked to fitness in this system, survival to adulthood, and senescence‐related traits. Juveniles born in seasons with higher food availability and into smaller natal groups (i.e., fewer competitors) were heavier. In contrast, there were no associations between juvenile body mass and genetic traits. Furthermore, size‐corrected mass—but not separate measures of natal food availability, group size, or genetic traits—was positively associated with survival to adulthood, suggesting juvenile body mass is indicative of natal condition. Heavier juveniles had greater body mass and had higher rates of annual survival as adults, independent of age. In contrast, there was no association between juvenile mass and adult telomere length attrition (a measure of somatic stress) nor annual reproduction. These results indicate that juvenile body mass, while not associated with senescence trajectories, can influence the likelihood of surviving to old age, potentially due to silver‐spoon effects. This study shows that measures of intrinsic condition in juveniles can provide important insights into the long‐term fitness of individuals in wild populations.
ddRAD‐Seq reveals evolutionary insights into population differentiation and the cryptic phylogeography of Hyporhamphus intermedius in Mainland China
Authors: Wang Gongpei , Lai Han , Bi Sheng , Guo Dingli , Zhao Xiaopin , Chen Xiaoli , Liu Shuang , Liu Xuange , Su Yuqin , Yi Huadong , Li Guifeng 
Published: July 2022

AbstractSpecies differentiation and local adaptation in heterogeneous environments have attracted much attention, although little is known about the mechanisms involved. Hyporhamphus intermedius is an anadromous, brackish‐water halfbeak that is widely distributed in coastal areas and hyperdiverse freshwater systems in China, making it an interesting model for research on phylogeography and local adaptation. Here, 156 individuals were sampled at eight sites from heterogeneous aquatic habitats to examine environmental and genetic contributions to phenotypic divergence. Using double‐digest restriction‐site‐associated DNA sequencing (ddRAD‐Seq) in the specimens from the different watersheds, 5498 single nucleotide polymorphisms (SNPs) were found among populations, with obvious population differentiation. We find that present‐day Mainland China populations are structured into distinct genetic clusters stretching from southern and northern ancestries, mirroring geography. Following a transplant event in Plateau Lakes, there were virtually no variations of genetic diversity occurred in two populations, despite the fact two main splits were unveiled in the demographic history. Additionally, dorsal, and anal fin traits varied widely between the southern group and the others, which highlighted previously unrecognized lineages. We then explore genotype–phenotype‐environment associations and predict candidate loci. Subgroup ranges appeared to correspond to geographic regions with heterogeneous hydrological factors, indicating that these features are likely important drivers of diversification. Accordingly, we conclude that genetic and phenotypic polymorphism and a moderate amount of genetic differentiation occurred, which might be ascribed to population subdivision, and the impact of abiotic factors.
Combined direct and indirect impacts of warming on the productivity of coral reef fishes
Authors: Millington Rebecca C. , Rogers Alice , Cox Peter , Bozec Yves‐Marie , Mumby Peter J. 
Published: July 2022

AbstractOcean warming is already causing widespread changes to coral reef ecosystems worldwide. Warming is having direct and indirect impacts on food webs, but their interaction is unclear. Warming directly affects fishes and invertebrates by increasing their metabolic rate, resulting in changes to demographic processes such as growth rates. Indirect effects involve a loss of reef habitat quality as coral bleaching reduces the availability of refuges. We used a size‐structured dynamic energy budget model of fishes and invertebrates, coupled to a spatially explicit model of coral and algae, to explore potential changes to ecosystem function with warming. Modeled changes in biomass for +3°C of warming were found to be controlled predominantly by the direct effects of warming on growth rates, rather than by indirect effects via the changed coral habitat. Crucially for fisheries, the biomass of predators decreased by at least 50% with +3°C of warming, and productivity of predators decreased by at least 60%.
Riverscape heterogeneity in estimated Chinook Salmon emergence phenology and implications for size and growth
Authors: Kaylor Matthew J. , Armstrong Jonathan B. , Lemanski Joseph T. , Justice Casey , White Seth M. 
Published: July 2022

AbstractMany salmonid‐bearing rivers exhibit thermal and hydrologic heterogeneity at multiple spatial and temporal scales, but how this translates into spatiotemporal patterns of fry emergence is poorly understood. Understanding this variability is important because emergence timing determines the biophysical conditions fish first experience (e.g., temperature, flow, and food supply), thereby influencing growth opportunities and survival during this critical life stage. We predicted spring Chinook Salmon (Oncorhynchus tshawytscha) emergence phenology across four northeastern Oregon subbasins over 5–9 years using empirical spawning and temperature data. We then related interannual emergence timing estimates to juvenile salmon size and growth rates at consistent sampling locations. There were clear longitudinal patterns of predicted emergence timing in each subbasin: The shape of these patterns was consistent among years, but not among subbasins. In two subbasins, emergence occurred progressively later with distance upstream, whereas in the other two subbasins emergence was earliest at upstream sites. Within each year, median emergence dates among sites within each subbasin ranged between 44 and 58 days. This spatial variation was comparable to interannual variation, with median emergence dates for a given location in each subbasin ranging between 47 and 74 days among years. Contrary to our expectations, juvenile salmon were not larger in years with earlier emergence, owing to slower estimated spring and summer growth rates compared to years with later emergence. Despite large interannual variation in estimated emergence dates, these results suggest that other factors (e.g., stream flow, temperature, and density‐dependence) were more important than growth duration in determining juvenile salmon growth rates and size among years. We demonstrated considerable spatial and interannual variation in emergence phenology within these subbasins. Understanding how this variation translates to spatiotemporal patterns of juvenile salmon habitat use, growth, and survival has important implications for guiding restoration efforts and understanding how climate change may impact these populations.
Efficient Dry Impregnation of Zirconium into H‐ZSM‐5 Zeolites
Authors: de Macedo Vinícius , de Lima Rafael O. P. , Piva Diogenes H. 
Published: July 2022

AbstractThere is considerable interest in adjusting the acidity and pore architecture of zeolites. Herein, we present solventless incorporation of zirconium (∼2–10 wt.%) in a precursor and desilicated (0.2 and 0.4 mol L−1 NaOH) H‐ZSM‐5 zeolite. Infrared and UV‐vis‐DR spectroscopy confirmed the grafting of highly dispersed Zr in all the zeolites. XRD indicated the presence of ZrO2 in zeolites with higher Zr contents. The micropore volume of the precursor zeolite decreased by ∼10 %, suggesting the presence of Zr mainly on the external surface, while it decreased more than 20 % for the desilicated sample, suggesting Zr had access to the micropores at higher Zr contents. Infrared spectroscopy after pyridine adsorption provided evidence for the Brønsted and Lewis acid sites in all zeolites, but the Brønsted acid‐to‐Lewis acid site ratio decreased by >50 % depending on the Zr and NaOH concentrations. The presence of Zr critically changed the predominant nature of the acid sites of the desilicated zeolites.
Cofluctuation analysis reveals aberrant default mode network patterns in adolescents and youths with autism spectrum disorder
Authors: Li Lei , Su Xiaoran , Zheng Qingyu , Xiao Jinming , Huang Xin Yue , Chen Wan , Yang Kaihua , Nie Lei , Yang Xin , Chen Huafu , Shi Shengli , Duan Xujun 
Published: July 2022

AbstractResting‐state functional connectivity (rsFC) approaches provide informative estimates of the functional architecture of the brain, and recently‐proposed cofluctuation analysis temporally unwraps FC at every moment in time, providing refined information for quantifying brain dynamics. As a brain network disorder, autism spectrum disorder (ASD) was characterized by substantial alteration in FC, but the contribution of moment‐to‐moment‐activity cofluctuations to the overall dysfunctional connectivity pattern in ASD remains poorly understood. Here, we used the cofluctuation approach to explore the underlying dynamic properties of FC in ASD, using a large multisite resting‐state functional magnetic resonance imaging (rs‐fMRI) dataset (ASD = 354, typically developing controls [TD] = 446). Our results verified that the networks estimated using high‐amplitude frames were highly correlated with the traditional rsFC. Moreover, these frames showed higher average amplitudes in participants with ASD than those in the TD group. Principal component analysis was performed on the activity patterns in these frames and aggregated over all subjects. The first principal component (PC1) corresponds to the default mode network (DMN), and the PC1 coefficients were greater in participants with ASD than those in the TD group. Additionally, increased ASD symptom severity was associated with the increased coefficients, which may result in excessive internally oriented cognition and social cognition deficits in individuals with ASD. Our finding highlights the utility of cofluctuation approaches in prevalent neurodevelopmental disorders and verifies that the aberrant contribution of DMN to rsFC may underline the symptomatology in adolescents and youths with ASD.
Agricultural activities and risk of central nervous system tumors among French farm managers: Results from the TRACTOR project
Authors: Petit Pascal , Gandon Gérald , Chabardès Stéphan , Bonneterre Vincent 
Published: July 2022

AbstractThe etiology of central nervous system (CNS) tumors is complex and involves many suspected risk factors. Scientific evidence remains insufficient, in particular in the agricultural field. The goal of our study was to investigate associations between agricultural activities and CNS tumors in the entire French farm manager workforce using data from the TRACTOR project. The TRACTOR project hold a large administrative health database covering the entire French agricultural workforce, over the period 2002‐2016, on the whole French metropolitan territory. Associations were estimated for 26 activities and CNS tumors using Cox proportional hazards model, with time to first CNS tumor insurance declaration as the underlying timescale, adjusting for sex, age and geographical area. There were 1017 cases among 1 036 069 farm managers, including 317 meningiomas and 479 gliomas. Associations varied with tumor types, sex and types of crop and animal farming. Analyses showed several increased risks of CNS tumors, in particular for animal farming. The main increases in risk were observed for meningioma in mixed dairy and cow farming (hazard ratio [HR] = 1.75, 95% confidence interval [CI]: 1.09‐2.81) and glioma in pig farming (HR = 2.28, 95% CI: 1.37‐3.80). Our study brings new insights on the association of a wide range of agricultural activities and CNS tumor and subtype‐specific risks in farm managers. Although these findings need to be corroborated in further studies and should be interpreted cautiously, they could have implications for enhancing CNS tumor surveillance in agriculture.
Pharmacy students' knowledge and confidence of COVID‐19 following an interactive didactic class
Authors: Kufel Wesley D. , Blaine Bruce E. , Avery Lisa M. 
Published: July 2022

AbstractBackgroundCOVID‐19 education for the pharmacy workforce is important to ensure pharmacists are optimizing patient care for the prevention and management of COVID‐19. However, there are currently no reports to our knowledge of education and training experiences for COVID‐19 prevention and management in the Doctor of Pharmacy (PharmD) curricula.ObjectiveTo evaluate pharmacy students' knowledge and confidence regarding COVID‐19 prevention and management before and after an interactive didactic class (IDC).MethodsA multicenter, quasi‐experimental, cross‐sectional survey study was performed among pharmacy students before and after IDC on COVID‐19 at two schools of pharmacy. The IDC on COVID‐19 consisted of student‐led presentations on a COVID‐19 drug, an infectious disease pharmacist faculty‐led interactive lecture on COVID‐19 prevention and management, and clinical case vignettes to assess COVID‐19 management strategies. An anonymous, voluntary, electronic survey was distributed to students (n = 85) before and after. The pre‐ and postintervention survey contained 10 COVID‐19 knowledge‐based questions and multi‐step, 5‐point Likert scale statements related to COVID‐19 prevention and management confidence. The postintervention survey also evaluated students' perceptions of the COVID‐19 IDC. Descriptive statistics were performed, and Student t test was used to compare pre‐ and postintervention responses.ResultsAbout 61 surveys were completed resulting in a response rate of 72%. COVID‐19 knowledge scores (mean ± SD) increased overall following the IDC (5.9 ± 1.31 vs 8.6 ± 1.29). Pharmacy students' COVID‐19 confidence scores (mean ± SD) also improved following the IDC (2.66 ± 0.75 vs 4.03 ± 0.53). Students performed well on the COVID‐19 clinical case vignettes with a mean ± SD score of 22.41 ± 0.46 out of 25. Pharmacy students' perceptions of the IDC on COVID‐19 were also positive overall.ConclusionPharmacy students' knowledge and confidence of COVID‐19 prevention and management improved following an IDC. This may be an effective strategy to provide COVID‐19 education during the PharmD curricula.
A qualitative analysis of bank credit risk disclosure: Evidence from the Canadian and Italian banking sectors
Authors: Lajili Kaouthar , Mohsni Sana , Polizzi Salvatore , Scannella Enzo 
Published: July 2022

AbstractThis paper aims to analyze bank credit risk disclosure practices in two different geographical contexts characterized by a homogeneous regulatory framework (Canada and Italy), by means of a qualitative content analysis methodology. We employ an innovative approach, which allows us to investigate both the qualitative and quantitative profiles of disclosures. Unlike an entirely quantitative approach, this comprehensive methodology allows us to analyze in depth the disclosure practices of Canadian and Italian banks and detect their commonalities, differences, points of strength, and weaknesses. Our results show that although there are some variations in the disclosure practices of Canadian and Italian banks, the quality of their disclosures is not significantly different. Among the most relevant differences, it emerges that while Italian banks provide more comprehensive disclosures, Canadian banks offer a more holistic view on credit risk. We contribute to the scant literature on credit risk disclosure by identifying room for improvement for both Canadian and Italian banks.
Oligofructose restores postprandial short‐chain fatty acid levels during high‐fat feeding
Authors: Meyer Rachel K. , Lane Adelina I. , Weninger Savanna N. , Martinez Taylor M. , Kangath Archana , Laubitz Daniel , Duca Frank A. 
Published: July 2022

AbstractObjectiveObesity is associated with consumption of a Western diet low in dietary fiber, while prebiotics reduce body weight. Fiber induces short‐chain fatty acid (SCFA) production, and SCFA administration is beneficial to host metabolic homeostasis. However, the role of endogenous SCFA signaling in the development of obesity is contentious. Therefore, the primary objective of this study is to evaluate the postprandial time course of SCFA production and uptake in healthy (chow‐fed), Western diet‐fed (high‐fat diet [HFD]) obese, and oligofructose‐treated HFD‐fed (HFD + OFS) rats.MethodsMale Sprague–Dawley rats were maintained on chow or HFD for 5 weeks, with or without supplementation of 10% OFS for 3 weeks. SCFAs were measured in the ileum, cecum, colon, portal vein, and vena cava at 0, 2, 4, 6, and 8 hours postprandially.ResultsPostprandial cecal and portal vein SCFAs were decreased in obese rats compared with lean chow controls, whereas no differences were observed in fasting SCFA concentrations. OFS supplementation increased SCFA levels in the cecum and portal vein during obesity. Butyrate levels were positively associated with portal glucagon‐like peptide 1 and adiposity and with Roseburia relative abundance.ConclusionsThe current study demonstrates that obesity is associated with reduced SCFA production, and that OFS supplementation increases SCFA levels. Additionally, postprandial butyrate production appears to be beneficial to host energy homeostasis.
Weight‐change trajectory in relation to cancer risk: findings from a nationwide cohort study in South Korea
Authors: Tran Thi Phuong Thao , Luu Ngoc Minh , Bui Thi Tra , Han Minji , Lim Min Kyung , Oh Jin‐Kyoung 
Published: July 2022

AbstractObjectiveThis study examined relationships between weight‐change trajectories and all cancers and obesity‐related cancer risks.MethodsA total of 1,882,304 men and 899,912 women from the 2002 to 2017 National Health Insurance Service cohort were included. Weight‐change trajectories in 2002 to 2009, according to BMI, were determined using group‐based trajectory modeling. Cox proportional hazards regression assessed associations between trajectories and cancer incidence.ResultsOverall, >50% of individuals maintained stable weight, as did two‐thirds of those in the overweight and obesity groups. A total of 64,725 men and 37,608 women developed incident cancer. Weight stability in overweight or obesity groups was associated with greater cancer risk. In both sexes, higher weight across BMI groups increased risks of all cancers, obesity‐related cancers and thyroid, colorectal, stomach, liver, prostate, and postmenopausal breast cancer. Stratified by BMI, weight gain increased risks of all cancers and obesity‐related cancers in men with obesity class I and women with overweight. Weight loss decreased risks of obesity‐related cancers, thyroid cancer, and kidney cancer among men with overweight, premenopausal breast, endometrial, and ovarian cancer in women with overweight, and obesity‐related cancers and thyroid cancer in women with class I obesity.ConclusionsMaintaining weight and avoiding weight gain are crucial for reducing cancer risk, but achieving a stable, normal BMI optimizes cancer prevention.
A randomized diet‐induced weight‐loss intervention reduces plasma complement C3: Possible implication for endothelial dysfunction
Authors: Jin Shunxin , Kusters Yvo H. A. M. , Houben Alfons J. H. M. , Plat Jogchum , Joris Peter J. , Mensink Ronald P. , Schalkwijk Casper G. , Stehouwer Coen D. A. , van Greevenbroek Marleen M. J. 
Published: July 2022

AbstractObjectiveComplement C3 and other components of the alternative pathway are higher in individuals with obesity. Moreover, C3 has been identified as a risk factor for cardiovascular disease. This study investigated whether, and how, a weight‐loss intervention reduced plasma C3, activated C3 (C3a), and factor D and explored potential biological effects of such a reduction.MethodsThe study measured plasma C3, C3a, and factor D by ELISA and measured visceral adipose tissue, subcutaneous adipose tissue, and intrahepatic lipid by magnetic resonance imaging in lean men (n = 25) and men with abdominal obesity (n = 52). The men with obesity were randomized to habitual diet or an 8‐week dietary weight‐loss intervention.ResultsThe intervention significantly reduced C3 (−0.15 g/L [95% CI: −0.23 to −0.07]), but not C3a or factor D. The C3 reduction was mainly explained by reduction in visceral adipose tissue but not subcutaneous adipose tissue or intrahepatic lipid. This reduction in C3 explained a part of the weight‐loss‐induced improvement of markers of endothelial dysfunction, particularly the reduction in soluble endothelial selectin and soluble intercellular adhesion molecule.ConclusionsDiet‐induced weight loss in men with abdominal obesity could be a way to lower plasma C3 and thereby improve endothelial dysfunction. C3 reduction may be part of the mechanism via which diet‐induced weight loss could ameliorate the risk of cardiovascular disease in men with abdominal obesity.
Comment on Comment on “Anomalous structural recovery in the near glass transition range in a polymer glass: Data revisited in light of temperature variability in vacuum oven‐based experiments”*
Authors: Jin Shuang , McKenna Gregory B. 
Published: July 2022

AbstractCangialosi, Alegría, and Colmenero have made a comment on a paper of ours [Polym. Eng. Sci. 2022:1–13], in which we discussed the concern that the enthalpy recovery data reported by Cangialosi and co‐workers [Phys. Rev. Lett. 2013;111(9):095701] for polystyrene aged up to 15 K below glass transition temperature was anomalous and contradicted existing experimental results from the literature over a similar range of aging conditions. Their response shifts the focus away from the raised questions about their experimental results and attempts to invalidate the data that we cited in support of our argument. Here we respond to the comment and add additional analysis that suggests the structural recovery response of glassy materials exhibits smooth behavior over the full range of measurements, up to 7 or 8 logarithmic decades. We do this by referring to the work on the intrinsic isotherm down‐jump and memory responses of poly(vinyl acetate) between 40°C and 15°C over six logarithmic decades by Kovacs [Fortsch. Hochpolym. Fo. 1963;3(1/2):394–508], the small‐strain tensile creep of poly(vinyl chloride) quenched from 90°C to 40°C (approximately 40°C below Tg) over seven logarithmic decades from Struik [Polym Eng. Sci., 1977;17:165–173], and the volume recovery behavior for aging times up to 3 months in a temperature range between 95°C and −50°C by Greiner and Schwarzl [Rheol. Acta. 1984;23(4):378–395]. We also add discussion that an isothermal aging procedure using a vacuum oven is highly vulnerable to temperature errors due to the problem of good temperature control when the heat transfer mechanism is primarily radiative.