bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coronary computed tomography angiography-based endothelial wall shear stress in normal coronary arteries
Authors: Schultz Jussi , van den Hoogen Inge J. , Kuneman Jurrien H. , de Graaf Michiel A. , Kamperidis Vasileios , Broersen Alexander , Jukema J. Wouter , Sakellarios Antonis , Nikopoulos Sotirios , Tsarapatsani Konstantina , Naka Katerina , Michalis Lampros , Fotiadis Dimitrios I. , Maaniitty Teemu , Saraste Antti , Bax Jeroen J. , Knuuti Juhani 
Published: October 2022

AbstractEndothelial wall shear stress (ESS) is a biomechanical force which plays a role in the formation and evolution of atherosclerotic lesions. The purpose of this study is to evaluate coronary computed tomography angiography (CCTA)-based ESS in coronary arteries without atherosclerosis, and to assess factors affecting ESS values. CCTA images from patients with suspected coronary artery disease were analyzed to identify coronary arteries without atherosclerosis. Minimal and maximal ESS values were calculated for 3-mm segments. Factors potentially affecting ESS values were examined, including sex, lumen diameter and distance from the ostium. Segments were categorized according to lumen diameter tertiles into small (< 2.6 mm), intermediate (2.6–3.2 mm) or large (≥ 3.2 mm) segments. A total of 349 normal vessels from 168 patients (mean age 59 ± 9 years, 39% men) were included. ESS was highest in the left anterior descending artery compared to the left circumflex artery and right coronary artery (minimal ESS 2.3 Pa vs. 1.9 Pa vs. 1.6 Pa, p < 0.001 and maximal ESS 3.7 Pa vs. 3.0 Pa vs. 2.5 Pa, p < 0.001). Men had lower ESS values than women, also after adjusting for lumen diameter (p < 0.001). ESS values were highest in small segments compared to intermediate or large segments (minimal ESS 3.8 Pa vs. 1.7 Pa vs. 1.2 Pa, p < 0.001 and maximal ESS 6.0 Pa vs. 2.6 Pa vs. 2.0 Pa, p < 0.001). A weak to strong correlation was found between ESS and distance from the ostium (ρ = 0.22–0.62, p < 0.001). CCTA-based ESS values increase rapidly and become widely scattered with decreasing lumen diameter. This needs to be taken into account when assessing the added value of ESS beyond lumen diameter in highly stenotic lesions.
Gray whale density during seismic surveys near their Sakhalin feeding ground
Authors: Gailey Glenn , Zykov Mikhail , Sychenko Olga , Rutenko Alexander , Blanchard Arny L. , Aerts Lisanne , Melton Rodger H. 
Published: October 2022

AbstractOil and gas development off northeastern Sakhalin Island, Russia, has exposed the western gray whale population on their summer-fall foraging grounds to a range of anthropogenic activities, such as pile driving, dredging, pipeline installation, and seismic surveys. In 2015, the number of seismic surveys within a feeding season surpassed the level of the number and duration of previous seismic survey activities known to have occurred close to the gray whales’ feeding ground, with the potential to cause disturbance to their feeding activity. To examine the extent that gray whales were potentially avoiding areas when exposed to seismic and vessel sounds, shore-based teams monitored the abundance and distribution of gray whales from 13 stations that encompassed the known nearshore feeding area. Gray whale density was examined in relation to natural (spatial, temporal, and prey energy) and anthropogenic (cumulative sound exposure from vessel and seismic sounds) explanatory variables using Generalized Additive Models (GAM). Distance from shore, water depth, date, and northing explained a significant amount of variation in gray whale densities. Prey energy from crustaceans, specifically amphipods, isopods, and cumaceans also significantly influenced gray whale densities in the nearshore feeding area. Increasing cumulative exposure to vessel and seismic sounds resulted in both a short- and longer-term decline in gray whale density in an area. This study provides further insights about western gray whale responses to anthropogenic activity in proximity to and within the nearshore feeding area. As the frequency of seismic surveys and other non-oil and gas anthropogenic activity are expected to increase off Sakhalin Island, it is critical to continue to monitor and assess potential impacts on this endangered population of gray whales.
Leaf-associated macroinvertebrate assemblage and leaf litter breakdown in headwater streams depend on local riparian vegetation
Authors: Oester Rebecca , dos Reis Oliveira Paula C. , Moretti Marcelo S. , Altermatt Florian , Bruder Andreas 
Published: October 2022

AbstractHeadwater streams harbor diverse macroinvertebrate communities and are hotspots for leaf litter breakdown. The process of leaf litter breakdown mediated by macroinvertebrates forms an important link between terrestrial and aquatic ecosystems. Yet, how the vegetation type in the local riparian zone influences leaf-associated macroinvertebrate assemblages and leaf litter breakdown rates is still not resolved. We investigated how leaf-associated macroinvertebrate assemblages and leaf litter fragmentation rates differ between forested and non-forested sites using experimental leaf litter bags in sixteen sites paired across eight headwater streams in Switzerland. Our results show that sensitive taxa of the invertebrate orders Ephemeroptera, Plecoptera and Trichoptera (EPT) and the functional group of shredders were strongly associated with forested sites with overall higher values of abundance, diversity, and biomass of EPTs in forested compared to non-forested sites. However, the importance of riparian vegetation differed between study regions, especially for shredders. Fragmentation rates, which are primarily the result of macroinvertebrate shredding, were on average three times higher in forested compared to non-forested sites. Our results demonstrate that not only the composition of the aquatic fauna but also the functioning of an essential ecosystem process depend on the vegetation type in the local riparian zone.
What Pre-clinical Rat Models Can Tell Us About Anxiety Across the Menstrual Cycle in Healthy and Clinically Anxious Humans
Authors: Pestana Jodie E. , Islam Nusaibah , Van der Eyk Natasha L. , Graham Bronwyn M. 
Published: October 2022

Abstract
Purpose of Review
Anxiety symptoms increase during the peri-menstrual phase of the menstrual cycle in people with anxiety disorders. Whether this reflects a heightened variant of normal menstrual-related changes in psychological states experienced by healthy (i.e. non-anxious) people is unknown. Moreover, menstrual-related change in anxiety symptoms is a poorly understood phenomenon, highlighting a need for pre-clinical models to aid mechanistic discovery. Here, we review recent evidence for menstrual effects on anxiety-like features in healthy humans as a counterpart to recent reviews that have focused on clinically anxious populations. We appraise the utility of rodent models to identify mechanisms of menstrual effects on anxiety and offer suggestions to harmonise methodological practices across species to advance knowledge in this field.

Recent Findings
Consistent with reports in clinical populations, some evidence indicates anxiety symptoms increase during the peri-menstrual period in healthy people, although null results have been reported, and these effects are heterogeneous across studies and individuals. Studies in rats show robust increases in anxiety during analogous phases of the oestrous cycle.

Summary
Studies in female rats are useful to identify the evolutionarily conserved biological mechanisms of menstrual-related changes in anxiety. Future experimental approaches in rats should model the heterogeneity observed in human studies to increase alignment across species and advance understanding of the individual factors that increase the propensity to experience menstrual-related changes in anxiety.
Update on Treatment Options for Stuttering Priapism
Authors: Hammad Muhammed A. Moukhtar , Soltanzadeh Zarandi Sina , Barham David W. , Yafi Faysal A. 
Published: October 2022

Abstract

Purpose of Review

There is a paucity of peer-reviewed evidence to guide medical management of stuttering priapism. The purpose of this review is to summarize the current understanding regarding the pathophysiology of priapism and management options for stuttering priapism.

Recent Findings
Conducting large-scale, randomized, placebo-controlled trials that elucidate the optimal treatment of stuttering priapism is challenging. Therefore, recent treatment guidelines are based upon small case series, retrospective studies, and expert opinions. Nonetheless, multiple compounds from various drug classes have shown promise in treating stuttering priapism, and a few pharmacotherapies such as Crizanlizumab are currently under active investigation.

Summary
Stuttering priapism is an under-investigated disorder with a complex pathophysiology. Currently, there is no wildly adopted universal therapeutic strategy. Further research is warranted to identify the appropriate treatment of stuttering priapism and to determine the long-term side effects of current pharmacotherapies.
Characterizing passenger-ship emissions: towards improved sustainability for MedMar fleet (gulf of Naples)
Authors: Spagnuolo Antonio , De Santo Giuseppe , Vetromile Carmela , Masiello Antonio , Di Costanzo Pierluigi , Esposito Salvatore , Buono Umberto , di Cicco Maria Rosa , Lubritto Carmine 
Published: October 2022

AbstractPromoting energetic and environmental sustainability in the naval sector requires a necessary understanding of the energy demand of vessels and of the factors affecting it. This article shows the results of a study conducted by the shipping company MedMar aimed at acquiring a detailed analysis of the energetic performances of its fleet. The study involved the analysis of fuel consumption and emissions of the fleet using a specific software and under different scenarios, assuming the navigation speed and the cargo level of the vessels as reference parameters. Simulations also provided a comparison, concerning emissions and externalities, between ships and two different means of transport. The purpose of this study was to identify potential areas of improvement, where ad hoc strategies could be used to further optimise the energetic and environmental performance of MedMar fleet and mitigate its impact on the delicate ecosystem of the gulf of Naples, where the fleet sails.
Antelope adaptations to counteract overheating and water deficit in arid environments
Authors: Blank David , Li Yaoming 
Published: October 2022

AbstractMany arid areas have very severe climates with extremely high summer temperatures, strong solar radiation, and a lack of drinking water during the driest season. Therefore, antelopes living in arid areas are forced to solve two main problems: avoiding overheating and maintaining water balance. Generally, there are physiological, morphological, and behavioral mechanisms for antelope adaptations to arid environments. Among the mechanisms, behavioral adjustments have a minimal cost and are activated first, while physiological mechanisms are the most energetically costly and involve adaptations to high temperatures when other mechanisms are insufficient. In previous publications, some examples of the antelope behavioral adaptations have been described only rarely, while in this review, we try to clarify all available information on the adaptations of antelopes living in arid areas to their native environments, paying particular attention to behavioral adjustments. Behavioral mechanisms, especially daily activity, diet and microclimate selection, and migrations, are so important and commonly used by antelopes in natural conditions, in which physiological mechanisms are usually not involved. Antelopes adjust their behaviors according to environmental changes so successfully that purely physiological mechanisms are discovered under laboratory conditions; for example, adaptive heterothermia or selective brain cooling phenomenon is difficult to observe in their natural habitats. This review provides a better understanding of the main behavioral mechanisms of antelope adaptations to arid environments and allows for the identification of the key factors for successful conservation of antelopes in their natural habitats.
Alternative High-Performance Fibers for Nonwoven HEPA Filter Media
Authors: Beckman Ivan P. , Berry Gentry , Cho Heejin , Riveros Guillermo 
Published: October 2022

AbstractContinual research, development, and advancement in air filtration technology is important to abate the ever increasing health hazards of air pollution and global pandemics. The purpose of this review is to survey, categorize, and compare mechanical and thermal characteristics of fibers to assess their potential applicability in air filter media. The history of high-efficiency particulate air (HEPA) filter development explains how we arrived at the current state of the art nonwoven fibrous borosilicate glass filter paper. This review explores the history and practical uses of particular fiber types and explains fiber production methods in general terms. The thermal and mechanical properties of particular fibers are examined using the codes and standards produced by the American Society of Mechanical Engineers (ASME) to generalize the applicability of fiber categories for HEPA filter units within the nuclear air cleaning industry. This review discusses common measurements for specific strength and tenacity used by the textile and construction industries. Particular fibers are selectively compared for density, tensile strength, tensile stiffness, flexural rigidity, moisture regain, decomposition temperature, and thermal expansion. This review concludes with a subjective assessment of which types of fibers may be appropriate to study for HEPA filtration.
Higher integrability for doubly nonlinear parabolic systems
Authors: Bögelein Verena , Duzaar Frank , Scheven Christoph 
Published: October 2022

AbstractIn this paper we establish a local higher integrability result for the spatial gradient of weak solutions to doubly nonlinear parabolic systems. The proof is based on a new intrinsic scaling that involves both the solution and its spatial gradient. It allows to compensate for the different scaling of the system in |u| and |Du|. The result covers the range of parameters $$p>\frac{2n}{n+2}$$

p
>

2
n

n
+
2

and $$0<q\le 1$$

0
<
q
≤
1

.
Making Sense of a Surprise: Perspectives on the 2020 “Belarusian Revolution”
Authors: Stykow Petra 
Published: October 2022

AbstractDrawing on three theoretical perspectives—“protest-democracy,” “authoritarian/patronal regime dynamics,” and “contentious politics”—developed in the study of popular protests in post-Soviet electoral autocracies, this article argues, first, that the 2020 postelection mobilization in Belarus was not to be expected for both structural and agency-related reasons. Second, by the summer of 2020, the political opportunity structure had opened up because of contingent choices by individual actors, with Alyaksandr Lukashenka committing several major mistakes, particularly on pandemic (non)control and the administration of the upcoming presidential election, and political newcomers taking on the role of challenging him. After the election, mass mobilization unfolded in two waves triggered by two additional regime mistakes: blatant electoral fraud and excessive repression. These mistakes served as focal points for spontaneous coordination, substituting for the deliberate “engineering” of protest by an organized opposition typical of the post-Soviet color revolutions. Third, Lukashenka survived in office because popular protests did not lead to elite defection. Instead, he was able to secure the loyalty of elites because he avoided gross blunders against both regime insiders and Russia. The case of Belarus indicates that hegemonic-authoritarian regimes are more vulnerable to mistakes by incumbents than to challenges from below and outside the regime.
A systematic review and meta-analysis of the evidence on inflammation in depressive illness and symptoms in chronic and end-stage kidney disease
Authors: Jayakumar Simone , Jennings Stacey , Halvorsrud Kristoffer , Clesse Christophe , Yaqoob Muhammad Magdi , Carvalho Livia A. , Bhui Kamaldeep 
Published: October 2022

AbstractBackgroundDepression affects approximately 27% of adults with chronic kidney disease (CKD) and end-stage kidney failure (ESKF). Depression in this population is associated with impaired quality of life and increased mortality. The extent of inflammation and the impact on depression in CKD/ESKF is yet to be established. Through a systematic literature review and meta-analysis, we aim to understand the relationship between depression and inflammation in CKD/ESKF patients.MethodsWe searched nine electronic databases for published studies until January 2022. Titles and abstracts were screened against inclusion and exclusion criteria. Data extraction and study quality assessment was carried out independently by two reviewers. A meta-analysis was carried out where appropriate; otherwise a narrative review of studies was completed.ResultsSixty studies met our inclusion criteria and entered the review (9481 patients included in meta-analysis). Meta-analysis of cross-sectional associations revealed significantly higher levels of pro-inflammatory biomarkers; C-reactive protein; Interleukin 6 (IL-6) and tumour necrosis factor-alpha in patients with depressive symptoms (DS) compared to patients without DS. Significantly lower levels of anti-inflammatory cytokine IL-10 were found in patients with DS compared to patients without DS. Considerable heterogeneity was detected in the analysis for most inflammatory markers.ConclusionWe found evidence for an association of higher levels of pro-inflammatory and lower anti-inflammatory cytokines and DS in patients with CKD/ESKF. Clinical trials are needed to investigate whether anti-inflammatory therapies will be effective in the prevention and treatment of DS in these patients with multiple comorbidities.
The Ecological Resonance of Imogen’s Journey in Montana’s Parks
Authors: Minton Gretchen E. , Gray Mikey 
Published: October 2022

In this article Gretchen Minton and Mikey Gray discuss an adaptation of Shakespeare’s tragicomedy Cymbeline that toured Montana and surrounding states in the summer of 2021. Minton’s sections describe the eco-feminist aims of this production, which was part of an international project called ‘Cymbeline in the Anthropocene’, showing how the costumes, set design, and especially the emphasis upon the female characters created generative ways of thinking about the relationship between the human and the more-than-human worlds. Gray’s first-person narrative at the end of each section reflects upon her role of Imogen as she participated in an extensive summer tour across the Intermountain West and engaged with audience members about their own relationship to both theatre and the natural world. This is a story of transformation through environmentally inflected Shakespeare performance during the time of a global pandemic.Gretchen E. Minton is Professor of English at Montana State University, Bozeman, and editor of several early modern plays, including Timon of Athens, Troilus and Cressida, Twelfth Night, and The Revenger’s Tragedy. She is the dramaturg and script adaptor for Montana Shakespeare in the Parks and the co-founder of Montana InSite Theatre. Her directorial projects include A Doll’s House, Timon of Anaconda (see NTQ 145, February 2021), Shakespeare’s Walking Story, and Shakespeare for the Birds. Mikey Gray received her BA in Theatre and Performance from Bard College, New York, with a conservatory semester at NIDA (National Institute of Dramatic Art) in Sydney. She has performed in four productions with Montana Shakespeare in the Parks, while other actor engagements include Chicago Shakespeare Theater, American Conservatory Theater, Strawdog Theater Company, The Passage Theatre, and McCarter Theatre Center.
Characterization and diversity of seed endophytic bacteria of the endemic holoparasitic plant Cistanche armena (Orobanchaceae) from a semi-desert area in Armenia
Authors: Petrosyan Kristine , Thijs Sofie , Piwowarczyk Renata , Ruraż Karolina , Vangronsveld Jaco , Kaca Wiesław 
Published: October 2022

AbstractWe explored the seed-associated bacterial endophytic microbiome in seeds of the endemic holoparasitic species Cistanche armena from a saline and arid habitat in Armenia. A combination of culture-dependent and molecular techniques was employed for identifying the seed endomicrobiome (culturable and unculturable). From surface-sterilized seeds, 10 phyla, comprising 256 endophytic bacterial genera, were identified. Of the culturable strains, we also investigated the plant growth-promoting (PGP) traits. Most of the isolates were spore forming, halotolerant and alkaliphile Bacillus spp., indicating that the endophytic bacteria of C. armena seeds own traits related to the natural habitat of their host plant. Our results confirm that Bacillus species are common and dominated endophytes from plants growing on saline and arid soils. Pantoea spp. and Stenotrophomonas spp. are more favourable PGP endophytes in seeds of C. armena. The PGP traits of these bacteria, such as production of indole, a precursor of auxin, ACC-deaminase and organic acids have the potential to improve the tolerance of their host plants against the abiotic stresses present in their natural habitat. To the best of our knowledge, this is the first report concerning bacterial seed endophytes of the C. armena.
What do we know about experiencing end-of-life in burn intensive care units? A scoping review
Authors: Ribeiro André Filipe , Pereira Sandra Martins , Nunes Rui , Hernández-Marrero Pablo 
Published: October 2022

AbstractObjectivesThe aim of this article is to review and synthesize the evidence on end-of-life in burn intensive care units.MethodsSystematic scoping review: Preferred Reporting Items for Systemic Reviews extension for Scoping Reviews was used as a reporting guideline. Searches were performed in 3 databases, with no time restriction and up to September 2021.ResultsA total of 16,287 documents were identified; 18 were selected for analysis and synthesis. Three key themes emerged: (i) characteristics of the end-of-life in burn intensive care units, including end-of-life decisions, decision-making processes, causes, and trajectories of death; (ii) symptom control at the end-of-life in burn intensive care units focusing on patients’ comfort; and (iii) concepts, models, and designs of the care provided to burned patients at the end-of-life, mainly care approaches, provision of care, and palliative care.Significance of resultsEnd-of-life care is a major step in the care provided to critically ill burned patients. Dying and death in burn intensive care units are often preceded by end-of-life decisions, namely forgoing treatment and do-not-attempt to resuscitate. Different dying trajectories were described, suggesting the possibility to develop further studies to identify triggers for palliative care referral. Symptom control was not described in detail. Palliative care was rarely involved in end-of-life care for these patients. This review highlights the need for early and high-quality palliative and end-of-life care in the trajectories of critically ill burned patients, leading to an improved perception of end-of-life in burn intensive care units. Further research is needed to study the best way to provide optimal end-of-life care and foster integrated palliative care in burn intensive care units.