bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of microsensors and support vector machines in the assessment of lower limb posture correction in adolescents
Authors: Zhang Yinman , Wang Lulu 
Published: July 2022

SummaryAutomatic monitoring of physical activity provides reliable data support for the maintenance of people's physical health and provides more scientific data for studying the relationship between physical activity and disease. In this article, a research on the evaluation of adolescent lower limb posture correction based on collaborative filtering and microsensors is carried out. Aiming at the problem that the human body posture monitoring system needs multiple nodes, this article simplifies the existing human body posture monitoring model and establishes a human body model with four degrees of freedom of the lower limbs. On this basis, the micro‐sensor assembly scheme and monitoring node layout scheme for obtaining model description parameters are determined. Methods such as collaborative filtering and support vector machines are used in the process of sensor data processing and correction effect evaluation. Finally, this article uses the constructed human body posture monitoring system to carry out the recognition test of the specific posture of the human body. The experimental results show that the evaluation scheme can effectively monitor and evaluate the effect of lower limb posture correction in adolescents.
Excess CO2 Reductions during CH3COOH Formation from CH4 and CO2 under Periodic Operation: Downhill Side Reactions in an Uphill Target Reaction under Unsteady Conditions
Authors: Nishimura Naoyuki , Onishi Kazuhiro , Tojo Masahiro 
Published: July 2022

AbstractAcetic acid (CH3COOH) formation from methane (CH4) and carbon dioxide (CO2) is an ideal reaction for chemical production, whereas this reaction possesses a severe thermodynamic limitation. To address this issue, it has been reported that periodic operation allowing a non‐equilibrium condition can overcome the thermodynamic limitation. However, although an intrinsic issue of uphill reactions in non‐equilibrium conditions generally is occurrence of unfavorable downhill reactions, this issue has seldom been discussed for the CH3COOH formation under periodic operation. Herein, excess CO2 reductions were found to be the unfavorable downhill reactions possibly occurring in the reaction aiming at CH3COOH formation under periodically operated CH4 and CO2 feeds. The reaction using an isotopic reactant (i. e., 13CH4) unveiled that excess CO2 reductions to CO and even to CH3 moiety could occur, indicating importance of catalyst development. Furthermore, it was proposed that H2O vapor introduction into the CO2 feed, which increased the CH3COOH product, most likely facilitated the reverse reaction of the excess CO2 reductions and thereby is effective to hamper the unfavorable side reaction.
Using base index for selection of St. Augustinegrass breeding lines evaluated in multienvironment trials for turfgrass quality traits and stress tolerance in North Carolina
Authors: Graham Sydney E. , Tome Gouveia Beatriz , Carbajal Esdras M. , Van der Laat Rocio , Milla‐Lewis Susana R. 
Published: July 2022

AbstractSt. Augustinegrass [Stenotaphrum secundatum (Walt.) Kuntze] is a warm‐season turfgrass primarily used for home lawns and commercial landscapes in the southern United States. New cultivars that possess desirable turfgrass quality (TQ) in combination with improved tolerance to diseases, drought and cold are needed to increase the sustainability of St. Augustinegrass production and maintenance in transitional zones. This study's objectives were to evaluate breeding lines in multienvironment trials across North Carolina to (a) assess relationships among economically important traits, and (b) select genotypes with stable performance across environments. Sixty‐one St. Augustinegrass genotypes and five commercial checks were established in replicated field trials at three locations across North Carolina. Entries were evaluated for rate of establishment, TQ, turfgrass stand density, genetic color, leaf texture, uniformity, winter survival, fall color, drought tolerance, and gray leaf spot resistance from 2017 to 2020. Best linear unbiased predictions were used to calculate a selection index to identify elite genotypes across traits. The 10 traits were clustered into three groups: winter survival and fall color; genetic color, leaf texture, and gray leaf spot resistance; and establishment rate, TQ, density, uniformity, and drought tolerance. Selection of the top 10 genotypes using the selection index resulted in positive estimated genetic gains for all 10 traits, indicating it is an effective method for simultaneous selection. Line XSA 14271 outperformed ‘Palmetto’, ‘Raleigh’, ‘Captiva’, and ‘Seville’, for several traits and was the top‐ranked line. It will be advanced to on‐farm trials to evaluate sod production traits to assess its potential for commercial release.
Association of ejection fraction with mortality and cardiovascular events in patients with coronary artery disease
Authors: Liu Yupeng , Song Jingjing , Wang Wenyao , Zhang Kuo , Qi Yu , Yang Jie , Wen Jun , Meng Xiangbin , Gao Jun , Shao Chunli , Tang Yi‐Da 
Published: July 2022

AbstractAimsRecent studies suggested that both left ventricular ejection fraction (LVEF) lower than 60% or higher than 65% were associated with an increased mortality in the general population. Uncertainty remains regarding adverse outcomes across LVEF in coronary artery disease (CAD). The common understanding was that LVEF <40% was associated with an increased risk of mortality. But the threshold at LVEF of 40% was arbitrary because quite a lot of adverse outcomes existed in patients with ejection fraction >40%. We aimed to evaluate the relationship between LVEF and mortality or adverse events in CAD patients undergoing percutaneous coronary intervention (PCI).Methods and resultsA total of 10 252 CAD patients undergoing PCI from an observational cohort were studied. All‐cause mortality and major adverse cardiovascular and cerebrovascular events (MACCE) were set as outcomes. Kaplan–Meier curves, adjusted Cox regression models, and restricted cubic spline analyses were used for evaluation. A total of 137 (1.3%) patients had all‐cause mortality, and 816 (8.0%) patients had MACCE during a median of 2.4 years of follow‐up. The median LVEF was 64%. All‐cause mortality and MACCE rates changed substantially across LVEF categories, and a linear inverse relationship of LVEF with all‐cause mortality and MACCE risk was observed. All‐cause mortality or MACCE risk increased significantly below an LVEF of 55 or 65%, respectively. Patients with LVEF <55% had a more than 3.5‐fold higher mortality than those with LVEF ≥55%. Patients with LVEF <65% had a more than 1.3‐fold higher MACCE than those with LVEF ≥65%. Below 55 or 65%, there was a rise in mortality or MACCE. A gradient–response relationship was observed, with an all‐cause mortality risk range between 8.6‐fold and 3.0‐fold increase from LVEF <40 to 50–54.9% and MACCE risk range between 2.4‐fold and 1.4‐fold from LVEF <40 to 60–64.9%.ConclusionsIn CAD patients undergoing PCI, LVEF lower than 55% or LVEF lower than 65% was correlated with increased all‐cause mortality and MACCE respectively, whereas higher LVEF was not.
Rhodium(I) Complexes Bearing Hydroxyl‐Functionalized 1,2,3‐Triazolylidenes and Their Catalytic Application
Authors: de la Fuente‐Olvera Agustín A. , Ruiz‐Mendoza Franciso J. , Vásquez‐Pérez José M. , Meléndez‐Rodríguez Myriam , Álvarez‐Hernández Alejandro , Salazar‐Pereda Verónica , Mendoza‐Espinosa Daniel 
Published: July 2022

AbstractWe report the straightforward synthesis and full characterization of a novel series rhodium(I) complexes (3 a–c) supported by hydroxyl‐functionalized 1,2,3‐triazolylidenes. All new compounds were fully characterized by means of 1H and 13C NMR spectroscopy, melting points, and elemental analyses. The new triazolylidene rhodium complexes 3 a–c were tested as catalysts in the hydrosilylation of terminal alkynes and the 1,4‐addition of boronic acid to 2‐cyclohexenone. Both catalytic processes provide good to excellent yields under low catalyst loadings and in the case of the hydrosilylation, a good selectivity toward the E‐isomer is observed.
DNA‐Templated Formation and N,O‐Transacetalization of N‐Methoxyoxazolidines
Authors: Aho Aapo , Österlund Tommi , Rahkila Jani , Virta Pasi 
Published: July 2022

AbstractDNA‐templated formation and N,O‐transacetalization of N‐methoxyoxazolidines have been studied. Compared to the reaction without a DNA‐catalyst, the hybridization‐driven N‐methoxyoxazolidine formation shows a marked rate acceleration, whereas the rate of corresponding N,O‐transacetalization is limited by the rate of decay to aldehyde intermediates. In both cases, the equilibrium yield increases markedly on the DNA template. Different hairpin architectures have been studied to evaluate the role and limits of the template effect. Furthermore, an attention has been paid to stereochemical integrity (R/S) of the N‐methoxyoxazolidine linkage. The N‐methoxyoxazolidine formation represents a dynamic pH‐responsive DNA‐templated ligation that occurs readily in slightly acidic conditions (pH 5).
α‐Angelica Lactone Catalyzed Oxidation of Pyrrolidines to Lactams
Authors: Deepake Siddharth K. , Kumar Manish , Kumar Pawan , Das Utpal 
Published: July 2022

AbstractHerein, we report an efficient protocol for the synthesis of γ‐lactams from pyrrolidines and oxygen. The strategy follows a two‐step process involving an initial generation α‐amino alkyl radicals from pyrrolidines and oxygen in presence of 4‐dimethylaminopyridine (DMAP) followed by trapping of the radical with oxygen species. This protocol demonstrates good functional group acceptance and provides a direct method to access γ‐lactams. The lactam derivatives were obtained in up to 98 % yield.
Adding Plasticizer Dispersible Conducting Polymer to the Ion‐selective Membrane Composition – Revitalizing Single Piece Ion‐selective Electrodes Concept
Authors: Jaworska Ewa , Maksymiuk Krzysztof , Michalska Agata 
Published: July 2022

AbstractTypically, ion‐selective electrodes used in current triggered electrochemical sensing apply a conducting polymer layer covered with an ion‐selective membrane. In this work we propose an ion‐selective membrane containing a dispersed conducting polymer. Thus obtained system allows elimination of the Achilles hell of heterogeneous ion‐selective membranes containing solid particulates dispersed within the ion‐selective polymeric membrane. The herein proposed system, even for high conducting polymer loading equal to 5 % w/w, is characterized with insensitivity towards redox interferences, as well as potentiometric detection limits, selectivity well comparable with that for other ion‐selective electrodes constructions. Under voltammetric conditions, with increasing loading of the conducting polymer in the membrane cathodic peak potentials are shifted towards more negative values, yet the linear dependence of the peak potential on logarithm of concentration of the analyte in the solution is preserved.
The physicochemical properties of the spirulina‐wheat germ‐enriched high‐protein functional beverage based on pear‐cantaloupe juice
Authors: Hassanzadeh Hamed , Ghanbarzadeh Babak , Galali Yaseen , Bagheri Hamed 
Published: July 2022

AbstractThe formulation of a novel functional juice, enriched with wheat germ powder and spirulina algae and based on cantaloupe and pear juice, was optimized by D‐optimal combined design. Firstly, sensory evaluation was performed by hedonic test to evaluate the organoleptic properties, and organoleptically desirable samples were screened for further experiments. Various chemical experiments including PH, acidity, formalin index, total phenol, flavonoids, antioxidant capacity, mineral contents (Fe, Zn, Ca, P, K, Mg, and Cu), and fatty acids profile were evaluated. The steady shear flow rheological test also was performed on the screened samples. The results of sensory evaluation showed that the samples containing 1% spirulina and wheat germ had the highest organoleptic score. The results of physicochemical tests on the selected samples showed that the addition of spirulina and wheat germ powder had little effect on pH, acidity, and formalin index but they affected brix, dry matter, and protein content. Also, the addition of spirulina and wheat germ powder, changed the amounts of antioxidant capacity (from 90 to 98%), total phenol (from 4 to 22 mg GAE/g), and flavonoid content (from 5 to 15 mg/L) in the functional beverages. Furthermore, the results of rheological tests showed that the addition of wheat germ powder in the functional fruit juices increased apparent viscosity however; spirulina did not affect important change in rheological properties. The GC‐Mass analysis presented fatty acid profiles of the functional beverages and confirmed the presence of polyunsaturated fatty acids (for example decanoic acid and heptadecanoic acid) in the samples.
Activin B promotes the initiation and progression of liver fibrosis
Authors: Wang Yan , Hamang Matthew , Culver Alexander , Jiang Huaizhou , Yanum Jennifer , Garcia Veronica , Lee Joonyong , White Emily , Kusumanchi Praveen , Chalasani Naga , Liangpunsakul Suthat , Yaden Benjamin C. , Dai Guoli 
Published: July 2022

Abstract
The role of activin B, a transforming growth factor β (TGFβ) superfamily cytokine, in liver health and disease is largely unknown. We aimed to investigate whether activin B modulates liver fibrogenesis. Liver and serum activin B, along with its analog activin A, were analyzed in patients with liver fibrosis from different etiologies and in mouse acute and chronic liver injury models. Activin B, activin A, or both was immunologically neutralized in mice with progressive or established carbon tetrachloride (CCl4)–induced liver fibrosis. Hepatic and circulating activin B was increased in human patients with liver fibrosis caused by several liver diseases. In mice, hepatic and circulating activin B exhibited persistent elevation following the onset of several types of liver injury, whereas activin A displayed transient increases. The results revealed a close correlation of activin B with liver injury regardless of etiology and species. Injured hepatocytes produced excessive activin B. Neutralizing activin B largely prevented, as well as improved, CCl4‐induced liver fibrosis, which was augmented by co‐neutralizing activin A. Mechanistically, activin B mediated the activation of c‐Jun‐N‐terminal kinase (JNK), the induction of inducible nitric oxide synthase (iNOS) expression, and the maintenance of poly (ADP‐ribose) polymerase 1 (PARP1) expression in injured livers. Moreover, activin B directly induced a profibrotic expression profile in hepatic stellate cells (HSCs) and stimulated these cells to form a septa structure. Conclusions: We demonstrate that activin B, cooperating with activin A, mediates the activation or expression of JNK, iNOS, and PARP1 and the activation of HSCs, driving the initiation and progression of liver fibrosis.
Bile acid conjugation deficiency causes hypercholanemia, hyperphagia, islet dysfunction, and gut dysbiosis in mice
Authors: Alrehaili Bandar D. , Lee Mikang , Takahashi Shogo , Novak Robert , Rimal Bipin , Boehme Shannon , Trammell Samuel A. J. , Grevengoed Trisha J. , Kumar Devendra , Alnouti Yazen , Chiti Katya , Wang Xinwen , Patterson Andrew D. , Chiang John Y. L. , Gonzalez Frank J. , Lee Yoon‐Kwang 
Published: July 2022

Abstract
Bile acid‐CoA: amino acid N‐acyltransferase (BAAT) catalyzes bile acid conjugation, the last step in bile acid synthesis. BAAT gene mutation in humans results in hypercholanemia, growth retardation, and fat‐soluble vitamin insufficiency. The current study investigated the physiological function of BAAT in bile acid and lipid metabolism using Baat

−/−
mice. The bile acid composition and hepatic gene expression were analyzed in 10‐week‐old Baat

−/−
mice. They were also challenged with a westernized diet (WD) for additional 15 weeks to assess the role of BAAT in bile acid, lipid, and glucose metabolism. Comprehensive lab animal monitoring system and cecal 16S ribosomal RNA gene sequencing were used to evaluate the energy metabolism and microbiome structure of the mice, respectively. In Baat

−/−
mice, hepatic bile acids were mostly unconjugated and their levels were significantly increased compared with wild‐type mice. Bile acid polyhydroxylation was markedly up‐regulated to detoxify unconjugated bile acid accumulated in Baat

−/−
mice. Although the level of serum marker of bile acid synthesis, 7α‐hydroxy‐4‐cholesten‐3‐one, was higher in Baat

−/−
mice, their bile acid pool size was smaller. When fed a WD, the Baat

−/−
mice showed a compromised body weight gain and impaired insulin secretion. The gut microbiome of Baat

−/−
mice showed a low level of sulfidogenic bacteria Bilophila. Conclusion: Mouse BAAT is the major taurine‐conjugating enzyme. Its deletion protected the animals from diet‐induced obesity, but caused glucose intolerance. The gut microbiome of the Baat

−/−
mice was altered to accommodate the unconjugated bile acid pool.
Factors predicting successful sperm retrieval in men with nonobstructive Azoospermia: A single center perspective
Authors: Aljubran Abdulkareem , Safar Omar , Elatreisy Adel , Alwadai Raed , Shalkamy Osama , Assiri Hassan Mohammed , Eskander Mamdoh , Arezki Adel , Ibrahim Ahmed 
Published: July 2022

AbstractPredicting successful sperm retrieval is essential in counseling infertile men with Azoospermia.ObjectivesTo assess the predictors of successful sperm extraction in men with nonobstructive Azoospermia.Patients and MethodsA retrospective study included all patients with nonobstructive Azoospermia from January 2018 to May 2019. Subdivided into two groups, group I (negative sperm retrieval) and group II (positive sperm retrieval).ResultsA total of 108 patients with a mean age of 36.8 ± 10 years were included. The rate of successful sperm retrieval was 47.2%. Group I included 57 patients (52.8%) with a mean age of 33.98 ± 6.18, and group II included 51 patients (47.2%) with a mean age of 40.04 ± 12.22 (p = 0.008). Follicular stimulating hormone (FSH) levels were significantly higher in group I (18.55 ± 13 vs. 7.97 ± 7.11; p < 0.004). Similarly, in group I, luteinizing hormone was significantly higher (11.4 ± 7.45 vs. 5.9 ± 4.4; p < 0.001). Age and FSH were the independent predictors of successful micro‐TESE. Additionally, successful pregnancies were 13.7% of patients, 28.6% of which gave rise to living birth.ConclusionPatients' age and serum FSH are independent predictors of successful sperm retrieval for infertile men with nonobstructive Azoospermia; young patients with high FSH levels could have little chance of sperm retrieval.
Developmental effects of siloxane exposure in zebrafish: A comparison study using laboratory‐mixed and environmental water samples
Authors: Jessup William H. , Wiegand Jenna , Delbridge‐Perry Mikayla , MacAvoy Stephen E. , Connaughton Victoria P. 
Published: July 2022

AbstractSiloxanes are used in personal care, biomedical, and industrial products. Their worldwide use and persistence in the environment cause consistent exposure for both humans and aquatic animals. Two siloxane congeners, decamethylcyclopentasiloxane (D5; CAS 541‐02‐6) and octamethylcyclotetrasiloxane (D4; CAS 556‐67‐2), are among the most prevalent, with measurable levels in air, sediment, water, and biological samples. However, few studies have examined the impact of developmental (embryo/larva) exposure. To address this gap, we performed parallel experiments using wildtype zebrafish (Danio rerio). One set of experiments used laboratory‐mixed individual solutions containing either D4, D5, or 2,4,6,8‐tetramethylcyclotetrasiloxane (D4H; CAS 2370‐88‐9); the other used environmental water samples containing a mixture of siloxanes, including D4 and D5. These samples were collected from Bladensburg Waterfront Park (BWP) a site along the Anacostia River, Washington, DC. In both experiments, zebrafish (24–48 h postfertilization, hpf) were exposed until 7 or 14 days (d)pf. Chronic exposure to D4, D5, or BWP water until 7 dpf caused stress‐like behaviors and reduced swim velocities; anatomical differences were noted only in BWP‐exposed larvae. At 14 dpf, BWP‐treated larvae still showed slower swimming velocities and increased immobility; anatomical differences were no longer evident and thigmotactic behavior was reduced. D4 and D5‐exposed larvae did not survive after 10 dpf. Larvae exposed to D4H showed no decreases in behavior or growth at either age. These results suggest early developmental sensitivity to siloxane exposure and point to the need to consider embryonic/larval endpoints when assessing aquatic contaminants.
Linguistic attributes and trade credit: Evidence from textual analysis of earnings conference calls
Authors: Fei Xingyuan , Xu Hongkang , Zhang Jiarui 
Published: July 2022

AbstractIn this study, we explore how the linguistic attributes of verbal language influence suppliers by focusing on trade credit using the earnings conference call setting. We hypothesize and find that suppliers tend to extend more trade credit to customers if managers of the customer firm use more positive tone relative to negative tone on conference calls, indicating that suppliers are likely to disentangle the positivity and negativity of managers’ tones of their customer firms on conference calls and adjust their trade credit strategy accordingly. We also find that suppliers are likely to grant less trade credit to customer firms if managers of the customer firm use more uncertainty and litigious words on calls. Our results are supported by a number of robustness tests. Overall, our results suggest that the linguistic attributes of customer firms on earnings conference calls have a significant impact on suppliers’ perception and assessment of future performance and uncertainty in customer firms.