bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mind Maps as a Tool for Visualization and Structuring of Linguistic and Literary Material in the Process of Teaching Students
Authors: Kachak Tetiana , Kachak Khrystyna 
Published: August 2022

The article reveals the peculiarities of the use of mental maps as a tool for visualization and structuring of linguistic and literary material in the process of teaching pedagogic students geared (“Primary Education”, “Philology”). The purposes of use, principles of creation, the maintenance of mental maps are outlined. The main purposes of their use are: systematization and structuring of educational information; analysis of the content of the submitted material; development of skills in working with primary and secondary information; formation of students’ skills of generating ideas; encouragement of independent critical, associative, logical, creative thinking; motivation and concentration increase. In the form of mental maps, you can work out a lecture or practical lesson on “Children’s Literature and methods of teaching literary reading", prepare a presentation of the writer’s work or analysis of the work, develop a methodological model of the lesson. In foreign language classes the mental maps can be used to generate associations at the initial stage of elaboration of the topic; systematization of vocabulary according to morphological or semantic criteria; structuring information obtained from certain media; visualization of grammatical rules and regularities; presentation of strategies for listening, speaking, reading, and writing. It is noted that the use of mental maps in the educational process contributes to the increase of students’ motivation and interest, activation of their cognitive, creative and mental activities.
DEMOGRAPHIC AND CLINICAL CHARACTERISTICS OF PATIENTS WITH COLON CANCER IN ISPARTA-BURDUR REGION
Authors: KAYIKÇIOĞLU Erkan 
Published: August 2022

Objective
To define the demographic and clinicopathological
characteristics of colon cancer patients followed up
at Suleyman Demirel University, Medical Oncology
Outpatient Clinic.
Material and Method
Outpatient archive files of 582 patients who applied
to Suleyman Demirel University Faculty of Medicine,
Medical Oncology Clinic and received a diagnosis of
colon cancer between 2010-2021 were examined and
patients’ age, gender, tumor location, family history
of cancer, and pathological TNM stage at the time of
diagnosis were recorded.
Results
Median age was 63.5 years. Of the 582 patients, 375
(64.4%) were male and 207 (35.6%) were female.
Thirty-four (5.8%) of the patients had family history
of colon cancer. The origin of the tumor was the right
colon in 147 (25.3%) patients, the left colon in 168
(28.9%), and the rectum in 265 (45.5%). At the time
of diagnosis, T stage was T1 in 35 (6%) patients,
T2 in 61 (10.5%), T3 in 418 (71.8%), and T4 in 67
(11.5%). Pathological N stage was N0 in 246 (42.3%)
patients, N1 in 168 (28.9%), and N2 in 168 (28.9%).
When staging was made according to TNM grades,
82 (14.1%) patients were diagnosed with Stage 1
disease, 153 (26.3%) with Stage 2 disease, 242
(41.6%) with Stage 3, and 105 (18%) patients were
diagnosed with Stage 4 disease. Metastasis was
detected at the time of diagnosis in 106 (18.2%) of
the patients.
Conclusion
Most of the patients who apply to Suleyman Demirel
University Faculty of Medicine, Medical Oncology
Outpatient Clinic from the Isparta-Burdur region are
patients diagnosed at an advanced stage. It is of
vital importance to raise awareness of colon cancer
screenings and increase awareness of colon cancer
in the community of this region.
Aggregate Airs: Atmospheres of Oil and Gas in the Greater Chaco
Authors: Grant Soni , Collective Editorial 
Published: August 2022

The author has identified a name change in the published article:

This Addendum relates to the following article: Grant, Sonia 2020. “Aggregate Airs: Atmospheres of Oil and Gas in the Greater Chaco.” Engaging Science, Technology, and Society 6: 534–554. https://doi.org/10.17351/ests2020.423

On page 534, the authors name is now “Soni Grant.”

The email address has also been updated to spgrant@dal.ca.
Clinical significance of assessing autoantibody level in diagnostics of early and late fetal growth retardation
Authors: Ignatko I. V. , Yakubova D. I. , Megrabyan A. D. , Timokhina E. V. 
Published: August 2022

Aim: to analyze diagnostic potential of early and late fetal growth retardation (FGR) based on examining significance of serum autoimmune antibody (АВ) level.Materials and Methods. A single center prospective cohort comparative study included 98 pregnant women: 79 with FGR (main group I) and 19 with physiological course of pregnancy (comparison group II). Depending on the time of manifestation, pregnant women with FGR were divided into 2 subgroups: early FGR (subgroup IA, n = 41) and late FGR (subgroup group IB, n = 38). All patients underwent venous blood sampling to determine the serum autoimmune AB level against 12 human self-antigens using the ELI-P-Test: for human chorionic gonadotropin antigen (hCG), DNA, β2-glycoprotein (β2-GP), collagen, fragment crystallizable of immunoglobulin G (Fc-IgG), insulin, thyroglobulin, S100 protein, surface antigen of germ cell and prostate (Spr), thrombocyte membrane protein (TrM), antineutrophil cytoplasmic antibodies (ANCA), and membrane antigen of glomerular cells (KiMS). Venous blood sampling was carried out in the main group at the time of establishing FGR diagnosis (the third trimester of pregnancy in all cases): early manifested FGR – 29 [28; 31] weeks, late manifested FGR – 5 [33; 36] weeks, comparison group II – 33 [32; 35] weeks.Results. To diagnose early FGR, the level of the following autoimmune АВ was shown to be significantly increased against hCG, collagen, S100 protein, TrM, ANCA, KiMS (p = 0.037; р = 0.001; р = 0.013; р = 0.005; р = 0.003; p < 0.001, respectively), whereas late FGR was diagnosed based on measuring АВ against DNA, collagen, insulin, S100 protein (p = 0.002; p = 0.003; p = 0.010; p < 0.001, respectively).Conclusion. Detecting autoimmune antibodies has shown its informative importance in pregnant women with FGR, so that changes in serum autoantibody level may serve as a laboratory marker of early and late FGR.
Monomeric form of C-reactive protein in the assessment of the residual inflammatory cardiovascular risk in patients with subclinical carotid atherosclerosis
Authors: Melnikov I. S. , Kozlov S. G. , Pogorelova O. A. , Tripoten M. I. , Saburova O. S. , Khamchieva L. Sh. , Avtaeva Yu. N. , Zvereva M. D. , Prokofieva L. V. , Kuznetsova T. V. , Guseva O. A. , Balakhonova T. V. , Gabbasov Z. A. 
Published: August 2022

Aim To study the relationship between monomeric C-reactive protein (mCRP) and the progression of asymptomatic carotid atherosclerosis in patients with a moderate risk for cardiovascular diseases (CVD) as assessed with the SCORE model.Material and methods The study included 80 men and women aged 53.1±5.8 years assigned to the category of a moderate risk for CVDs by the SCORE model with a low-density lipoprotein cholesterol (LDL-C) level of 2.7–4.8 mmol/l and asymptomatic, hemodynamically insignificant (<50% luminal narrowing) carotid atherosclerosis according to ultrasonic data. All patients were prescribed atorvastatin to achieve a LDL-C level <2.6 mmol/l. After 7 years of follow-up, ultrasonic examination of carotid arteries was performed, and concentrations of high-sensitivity C-reactive protein (hsCRP) and mCRP were measured.Results A concentration of LDL-C <2.6 mmol/l was achieved in all patients. The progression of atherosclerosis as determined by an increased number of atherosclerotic plaques (ASPs), was observed in 45 (56 %) patients. At 7 months of follow-up, concentrations of cCRP were higher in the group of patients with progressive carotid atherosclerosis, while the levels of hsCRP did not differ between the groups. Increased mCRP concentrations were associated with changes in variables of the “atherosclerotic load”, including the number of ASPs, total ASP height, and the intima-media thickness (IMT). In patients with a median mCRP concentration of 5.2 [3.3; 7.1] µg/l and more, the increases in mean ACP number and total ASP height were considerably higher than in patients with mCRP concentrations lower than the median (3.9 and 2.7 times, respectively), whereas the odds ratio for the progression of asymptomatic carotid atherosclerosis was 5.5 (95 % confidence interval, CI: 2.1–14.6; p=0.001). ROC analysis showed that the concentration of hsCRP had no predictive value for prognosis of asymptomatic carotid atherosclerosis (p=0.16), while the area under the ROC curve (AUC) for mCRP was 0.75±0.056 (95 % CI: 0.64–0.86; p=0.001).Conclusion According to the results of 7-year follow-up, the plasma concentration of mCRP was significantly higher in patients with an increased number of ASPs than in patients without this increase. An increased level of mCRP may indicate a higher inflammatory risk of CVD.
The state of platelet and plasma hemostasis as a predictor of coronary blood flow in patients with acute myocardial infarction
Authors: Duhin O. A. , Kalinskaya A. I. , Rusakovich G. I. , Anisimova A. S. , Netylko J. E. , Polyakov P. A. , Vasilieva E. Yu. , Shpektor A. V. 
Published: August 2022

Aim To study the relationship of the platelet function and plasma homeostasis with the blood flow in the infarct-related artery (IRA) and with the course of acute myocardial infarction (AMI).Material and methods This study included 93 patients with AMI (75 patients with ST-elevation AMI and 18 patients without ST segment elevation). 63 patients had TIMI 0-1 blood flow in the IRA and 30 patients had TIMI 2–3. Rotational thromboelastometry, impedance aggregometry, the endothelium-dependent vasodilation (EDVD) test, and the thrombodynamics test were performed for all patients. The primary clinical endpoint included the totality of in-hospital complications of AMI, and the secondary endpoint included the totality of out-of-hospital complications of AMI. Major bleedings (BARC 3-5) and minor bleedings (BARC 1-2) were evaluated separately.Results Patients with IRA TIMI 0–1 flow were characterized by a shorter blood clotting time (BCT), larger thrombus size and density, more intense platelet aggregation induced by arachidonic acid and ADP, and lower values of the EDVD test. It was found that the parameters of platelet aggregation induced by arachidonic acid (AUC Asa) in combination with BCT allowed assessment of the severity of IRA blood flow disorder (sensitivity 76 %, specificity 71 %) in patients with AMI, regardless of the presence of ST segment elevation on the ECG. In addition, the incidence of the primary endpoint was greater in patients with IRA TIMI 0–1 flow (41.3% and 16.7%, respectively; p=0.015). In patients with TIMI 2–3 flow in the long-term period of the disease, the incidence of minor bleedings was significantly higher (8.5% and 30.4 %, respectively; p=0.045).Conclusion Compared to patients with preserved blood flow, patients with AMI and IRA TIMI 0–1 flow are characterized by endothelial dysfunction and more intense processes of thrombogenesis and platelet aggregation. It has been shown for the first time that the combination of two simple criteria for assessing hemostasis (AUC Asa; BCT) allows assessment of the degree of IRA blood flow disorder in patients with AMI.
Optimalisasi Pemanfaatan Platform Digital Untuk Kegiatan Ngaji Online di Pondok Pesantren
Authors: Yamani Achmad Zaki 
Published: August 2022

Salah satu Program strategis Badan Aksesibilitas Telekomunikasi dan Informasi (BAKTI) adalah terkait penyediaan akses internet di seluruh Indonesia, khususnya daerah 3T, yaitu daerah tertinggal, terdepan dan terluar, adapun Akses Internet tersebut diantara penerima manfaatnya yaitu adalah pondok pesantren. Di lain sisi, tantangan pondok pesantren dewasa ini semakin terasa dengan munculnya wabah pandemi Covid-19, dimana proses belajar mengajar, utamanya perihal kegiatan mengaji tetap harus berlangsung walau ditengah pandemic dengan segala aturan-aturan turunanya yang membatasi interaksi pembelajaran langsung. Oleh karenanya upaya-upaya optimalisasi pemanfaatan akses internet untuk mendukung kegiatan ngaji online di pesantren menjadi suatu keharusan melalui optimalisasi media digital untuk memastikan kualitas pendidikan di pondok pesantren berjalan dengan baik . Adapun dari kegiatan ini, pesantren yang berpartisipasi aktif terhadap kegiatan ngaji online sebanyak 18 Pondok Pesantren, 11 diantaranya masih melanjutkan kegiatan ngaji online hingga saat ini atau setara dengan 61,11% dari seluruh Pondok Pesantren yang mengikuti kegiatan ini.
Peningkatan Pemahaman Implementasi Data Mining bagi Siswa SMK Dharma Wanita Gresik
Authors: Mar'i Farhanna , Husenti Nadya , Bahiyyah Choridatul , Ubaidillah Hafidz 
Published: August 2022

Seiring berkembangnya teknologi informasi pada revolusi industri 4.0 diperlukan teknik implementasi Data Mining untuk menggali pengetahuan pada data untuk dapat dimanfaatkan sebaik-baiknya. Pengenalan implementasi Data Mining pada siswa SMK khususnya pada jurusan Rekayasa Perangkat Lunak (RPL) sangat penting untuk dilakukan untuk membekali siswa tentang implementasi Data Mining pada proses perancangan Aplikasi. Berdasarkan hasil wawancara yang dilakukan oleh tim Pengabdian Kepada Masyarakat (PKM) Program Studi Teknik Informatika Universitas Muhammadiyah Gresik dengan pihak SMK Dharma Wanita Gresik khususnya di kelas XII jurusan Rekayasa Perangkat Lunak diketahui bahwa siswa belum pernah diberikan pembekalan ilmu mengenai implementasi Data Mining. Sehingga kegiatan peningkatan pemahaman implementasi Data Mining pada siswa SMK Dharma Wanita Gresik khususnya pada Jurusan Rekayasa Perangkat Lunak dilakukan dengan cara melakukan sosialisasi ilmu Data Mining disertai dengan pelatihan mengenai penggunaan salah satu tools Data Mining yaitu Rapid Miner. Adapun hasil yang tercapai dari kegiatan PKM ini adalah adanya peningkatan pemahaman dan kemampuan siswa SMK Dharma Wanita Gresik jurusan Rekayasa Perangkat Lunak mengenai Data Mining dan teknik implementasinya pada data nyata yang diukur menggunakan post test.
Effects of the coupling between slope morphology and bottom currents on flow erosion and sedimentation at the Dongsha Continental Margin, South China Sea
Authors: Wang Hairong , Yu Chengqian , Huo Zhipeng , Gao Hongfang , Jiang Wen 
Published: August 2022

Abstract
The Dongsha Continental Margin (DCM) projects seaward and is situated in the path of bottom currents coming through the only deep-water exchange passage, the Luzon Strait between the South China Sea (SCS) and the western Pacific Ocean. This provides an opportunity to observe the different interaction between the two wings of the convex margin and the bottom currents, and help understand the corresponding implications for provenance, debris transportation, and sedimentation in such an environment. The convexity of the DCM causes its eastern flank to shrink against upcoming bottom currents and internal solitary waves (ISWs), producing a funneling effect and forming strong erosion grooves or strips, remnant seamounts, and large seafloor coarse debris dunes. The concavity of the western flank induces the expansion of bottom currents that flow around the plateau, resulting in a depositional zone with weak erosion that mainly interacts with bottom currents and gravity flow. The strong erosion on the DCM caused by the bottom current forms the primary provenance of the deep-water environment, while the nepheloid layer that entraps the fine debris of the gravity flow that derives from Taiwan and that is transported by the bottom current is the secondary provenance. The different coupling patterns between the bottom currents and the two flanks determine the different modes of debris transportation and deposition. Debris eroded by the currents is mainly transported by the gravity flow on the eastern flank while sweeping of the outer shelf and upper slope by eddy currents, progradation of the gravity flow, and reworking by the bottom current mainly occur on the western flank. Two types of morphological breaks, namely, continental slope break and bottom-current slope break, have developed on the DCM. They control the evolution of the flow regime of the multi-layer bottom currents and the gravity flow of the DCM as well as the effects of erosion and deposition. These two types of slope breaks are coupled and form an area in front of Dongsha Island with the highest deposition rate in the SCS.
A Combined Thermal Spallation and Melting Technology by Plasma Jet for Deep and Hard Rock Reservoirs
Authors: Sun Qiang , Liu Yonghong , Shen Zhiping , Han Yancong , Wang Qingxiang , Liu Peng 
Published: August 2022

Summary
With the increasing demand for oil, gas, and geothermal resources worldwide, the efficient and economical construction of wells in deep and hard rocks has become very important, but conventional mechanical drilling technology cannot achieve this. In this paper, a new noncontact combined thermal spallation and melting technology by plasma jet is proposed. This technology can excavate rock materials by disintegrating brittle rocks into small fragments and melting plastic rock. Especially for hard granite, this method exhibits high rock removal efficiency with low specific energy. Furthermore, the plasma bit is not in contact with the rock, thus avoiding bit wear. A thermal spallation and melting experiment system is established, and laboratory tests are conducted. The influence of plasma current, plasma gas flow rate, confining pressure, and the types of rock-on-rock removal efficiency and specific energy are also researched. Results show that this novel technology can efficiently remove hard rocks, and hard granite is more likely to be removed under confining pressure than under the absence of confining pressure, indicating the feasibility of accessing geothermal, oil, and gas resources from deep and hard rock formations.
Effect of a positive cumulative fluid balance on the prognosis of patients with sepsis in the Xining area
Authors: Ma Si-Qing , Wang Yun , Sun Bin , Wang Hao , Xu Xue-Xia , Yin Zhi-ying , Luo Junming 
Published: August 2022

Abstract
Background: The aim of this work is to analyze the effect of a positive cumulative fluid balance and relative clinical indicators on the prognosis of patients with sepsis in the Xining area, China.Methods: The clinical data of 480 sepsis patients (313 males and 167 females, aged 52–77 (65) years) admitted between January 2017 and December 2019 were retrospectively analyzed. The APACHE II score, SOFA score, SIRS score and clinical laboratory test indicators of the patients were collected. Receiver operating characteristic (ROC) curves were used to analyze the sensitivity and specificity of each indicator in predicting the poor prognosis of patients with sepsis, and the maximum Youden index was used to determine threshold values. Cox regression analysis was performed to assess patient prognosis using data from patients with different fluid balances. Results: The following clinical indicators were significantly different between the 2 groups (P<0.05): APACHE II score, SOFA score, SIRS score, PCT, IL-6, BNP, CRP, PLT, BUN, CREA, Lac and total fluid balance from days 1 to 5. The area under the ROC curve (AUC) for total fluid balance from days 1 to 5 was 0.558, the cut-off value was 2120.5 mL, the sensitivity was 54.0%, and the specificity was 58.1%. The survival rates were different between the 2 groups (60.9% vs 48.9%, P<0.05). Total fluid balance was significantly higher in patients with septic shock and with Lac>2.0 mmol/L (P<0.05). Cox regression analysis indicated that APACHE II score, SOFA score, PLT score, Lac, and total fluid balance from days 1 to 5 were independent risk factors for poor prognosis.Conclusion: A positive fluid balance from days 1 to 5 after ICU admission was associated with poor patient outcomes and was an independent risk factor for poor patient prognosis.
Purification and enzymatic properties of a new thermostable endoglucanase from Aspergillus oryzae HML366
Authors: Qin Yongling , Qin Baoshan , Zhang Jian , Fu Yue , Li Qiqian , Luo Fengfeng , Luo Yanmei , He Haiyan 
Published: August 2022

Abstract
Aspergillus oryzae HML366 is a newly screened cellulase-producing strain. The endoglucanase HML ED1 from A. oryzae HML366 was quickly purified by two-step method ammonium sulfate precipitation and strong anion exchange column. SDS-PAGE electrophoresis indicated that the molecular weight of the enzyme was 68 kDa. The optimum temperature of the purified endoglucanase was 60 ℃ and the enzyme activity was stable below 70 ℃. The optimum pH was 6.5, and the enzyme activity was stable at pH between 4.5 to 9.0. The analysis indicated that additional Na+, K+, Ca2+, and Zn2+ reduced the catalytic ability of enzyme to the substrate, but Mn2+ enhanced its catalytic ability to the substrate.The Km and Vmax of the purified endoglucanase was 8.75 mg/mL and 60.24 μmol/min·mg, respectively. In this study, we for the first time reported that A. oryzae HML366 can produce a heat-resistant and wide pH tolerant endoglucanase HML ED1, which has potential industrial application value in bioethanol, paper, food, textile, detergent and pharmaceutical industries.
STL decomposition based LSTM model for seasonal agricultural price forecasting
Authors: JAISWAL RONIT , JHA GIRISH KUMAR , CHOUDHARY KAPIL , KUMAR RAJEEV RANJAN 
Published: August 2022

Abstract
In this study, we integrated a decomposition technique viz. seasonal trend decomposition procedure based on loess (STL) with an efficient recurrent neural network-based forecasting technique, i.e. long short-term memory (LSTM) and developed an ensemble hybrid model called STL-LSTM for a non-stationary, nonlinear and seasonal agricultural price series. First, the STL technique is used to decompose the original price series into the seasonal, trend and remainder components. Then, an LSTM network with a single hidden layer is constructed to forecast these components individually. Finally, the prediction results of all components are aggregated to formulate an ensemble output for the original agricultural price series. The hybrid model captures the temporal patterns of a complex time series effectively through analysis of the simple decomposed components. The study further compared the price forecasting ability of the developed STL-LSTM model with the other potential models using monthly price series of potato for two major markets of India. The empirical results demonstrated the superiority of the developed hybrid model over the other models in terms of root mean square error (RMSE) and mean absolute percentage error (MAPE). Moreover, the accuracy of the forecasts obtained by all the models is also evaluated using the Diebold-Mariano test. All criteria show that the STL-LSTM based model has a clear advantage over the other models.
Vascular Remodelling After Anti-vegf Treatment in Patients With Neovascular Age-related Macular Degeneration
Authors: Kirkova Radina , Murgova Snejana , Tanev Ivan 
Published: August 2022

Abstract
Background:Age-related macular degeneration (AMD) is a progressive, degenerative disease of the central retina. AMD is subdivided into “dry” (atrophic), “wet” (exudative) and neovascular (nAMD) forms. In recent years, the concepts about nAMD changed with the development of optic coherence tomography – angiography (OCT-A) and intravitreal anti-VEGF treatment. The aim of this study is to define the morphologic type of the neovascular membrane (NVM) before treatment with OCT-A and to register vascular remodeling after treatment with anti-VEGF. We also analyzed the relationship between NVM and visual acuity.Methods:The study is retrospective and includes 119 patients, with newly diagnosed, treatment naïve nAMD. All the patients underwent full ophthalmic examination and also fluorescine angiography and optic coherence tomography – angiography (OCT-A). Results:Based on the collected data, we found repetitive regularities.Conclusion:The analysis of our results could be used as prognostic markers for the evolution of the disease and as a basis for new treatment strategies, depending on the naïve NVM morphologic type.