bluuebunny/crossref_metadata_2025_split huggingface dataset:
Applying artificial intelligence methods for solving problems of searching for semantic associates: case of toponym Moskva
Authors: Borovsky Andrei Viktorovich , Rakovskaya Elena Evgenievna 
Published: April 2022

Actual problems of toponymy imply the study of individual words in order to restore the conceptual meaning of geographical names lost, to find out how they reflected the characteristic features of the terrain, the type of ac-tivity of the people inhabiting it, etc. The purpose of the study is to determine the origin of the toponym Moskva by using artificial intelligence methods. The GeoWAC fastText embedding model based on the corpus of Russian-language texts of the RusVecteres service is used to calculate semantic similarity between words. The model assumes defining the semantic associates of toponyms by using the vector representation of words in the semantic space and finding the lexical vectors most closely located to the vector of the original word. To analyze a toponym there is applied a methods of semantic associates, a cluster analysis, a combined method based on the method of transformation of a word with a lost meaning and the analysis of semantic associates for a set of word transformants. The method is formalized by using a model that determines the similarity of the studied word and associates based on different versions of the model for one or more text corpora. The associated words obtained by the artificial intelligence are considered as a semantic cluster, and the calculated cosine similarity between vectors is considered as a measure of the similarity of elements in the cluster. To identify various hypotheses of the origin of the toponym Moskva there has been carried out a cluster analysis of the totality of the first ten vector associates for all transformants of this word. As a result, four hypotheses were advanced: “a famous man”, “firearms”, “beekeeping”, “blood-sucking insects”. The probabilities of the occurrence of these hypotheses are based on the study of the frequency of words in the corpus
of the language. The main hypothesis is a “famous person”.
Numerical-analytical transformation method of analyzing nonlinear mathematical models with polynomial structure
Authors: Ivanov Sergei , Televnoy Andrey 
Published: April 2022

The article considers a scientific problem of investigating mathematical models with polynomial nonlinearity, which are represented by systems of nonlinear differential equations. There is presented a numericall-analytical transformation method for investigating nonlinear dynamical systems with many degrees of freedom of polynomial structure. As opposed to the analogues, this method allows solving a wide range of problems for nonlinear systems
of general polynomial structure while reducing the computational resource intensity. An algorithm of the method
of transformations for investigating the nonlinear dynamic systems with m degrees of freedom is given. The research of stability of solutions of nonlinear dynamic systems with m degrees of freedom is carried out. Algorithmic formulas of transformation method for the solution of systems with nonlinearity of the fourth degree are given. Computational experiments on solving systems of differential equations with a small nonlinear part in the form of a multinomial
of the sixth degree using the transformation method show fourth order accuracy in computation. A nonlinear mathematical model of the vibration protection system is investigated by the presented method of transformations. The theorem on determination of the stationary state for systems of differential equations of polynomial structure by transformation method is proved. Algorithmic formulas for computation are presented. A general matrix form for vector indices is presented. Formulas for economical computation of right-hand sides of polynomial structure are presented and it is proposed to apply Pan's scheme with coefficient preprocessing. This method allows studying the different modes
of nonlinear models dynamics, for example, to determine such extreme modes as resonance, sub-harmonic, and polyharmonic modes. As an example of the method application, the vibration protection problem of the tower from external periodic influences was solved. The transformed solution takes into account all nonlinear polynomial components. The method allows to investigate the dynamics of a wide range of nonlinear systems with the necessary accuracy
Information and telecommunication resources of critical infrastructures: features of interval security analysis
Authors: Kotenko Igor Vitalievich , Parashchuk Igor Borisovich 
Published: April 2022

The object of the research is a new methodological approach to solving the problem of interval analysis
of the security of information and telecommunication resources of critical infrastructures. This approach is one of the variants of practising the methods of the class midvalues (interval calculations). The approach characteristics were analyzed to determine its validity and usefulness for assessing the security indicators of such complex technical systems over a time interval. There have been considered theoretical aspects of building the algorithms for calculating the class midvalues of security levels of information and telecommunication resources of critical infrastructures, factors of calculating the upper and lower class midvalues of security levels. A sequence of calculations and analytical expressions for calculations on the example of a specific security indicator are proposed. The approach offers taking into account the modern requirements of security management subsystems of complex technical systems, the requirements of officials (auditors, security administrators) related to the inertia of decision-making processes, with the duration of cycles of security control and security management of systems of this class. It allows one to obtain not point (instantaneous), but interval estimates of security indicators, while the analysis is carried out with a predetermined frequency and takes into account the uncertainty of the initial data – observed and controlled security indicators. At the same time, interval analysis does not have great mathematical and computational complexity, but it allows one to obtain interval estimates of resource security adequate to control and management tasks, saves computing resources and, ultimately, works
to increase the reliability of security control of modern critical infrastructures
Diagnosis and management of obstructive urolithiasis in miniature pigs
Authors: Simpson Katharine M. , Oman Rachel E. , Depenbrock Sarah M. 
Published: April 2022

Abstract
This article provides information to assist practitioners in the diagnosis, medical, and surgical management of obstructive urolithiasis in miniature pigs. The article focuses primarily on pigs managed as pets because production swine rarely undergo intensive treatment for urolithiasis. As much as possible, the information in this article is based on published literature, but given the limited number of publications addressing obstructive urolithiasis in pigs, some information is based on the authors’ clinical experience. Medical and surgical management of obstructive urolithiasis of pigs is often similar to management in ruminant and small animal species, but differences in swine anatomy, handling, and temperament create unique challenges. Pigs tend to be more difficult to restrain and examine than other livestock and often require heavy sedation or anesthesia to facilitate physical examination and basic diagnostic procedures. Because pigs are monogastrics, some oral treatments used in small animals may be used effectively in pigs. Clinicians should follow AMDUCA and consult the Food Animal Residue Avoidance Databank prior to extralabel drug use because pet pigs are still considered a major food-producing species in the United States.
Direct Fixation of Fractures of the Posterior Malleolus Through a Postero-Medial Approach
Authors: Andonov Y. , Parashkevova P. 
Published: April 2022

Abstract

Background and objective: Fractures of the posterior malleolus have long been neglected in the past. The decision for their fixation should be based on plain lateral radiographs. Recent studies have emphasized the important biomechanical function of the posterior tibial ridge. This has caused a trend towards more aggressive surgical treatment. The aim of this study was to present our experience with the direct fixation of complex ankle fractures engaging the posterior malleolus. We also tried to clarify the advantages and limitations of the posterior-medial surgical approach.

Materials and Methods: For a period of 1,5 years we have operated 14 patients with posterior malleolus fractures. Their average age was 51 years. Eight of the patients were male, the rest 6 were females. Fractures were classified according to Bartoníček classification system. All patients had type 3 fractures. Direct open reduction was performed in all cases. Posterior buttress plate was used for the fixation of the fracture. Bone grafting was found necessary in one case. Functional assessment was done according to the criteria of the AOFAS (American Orthopedic Foot and ankle score). Follow up was done for an average period of 10 months.

Results: All fractures united for an average period of 9 weeks (8-10 weeks). Six patients achieved an excellent functional result, 5 – a good one and 3 had an average result. The average AOFAS rating score was 84,02 (54-100). The average range of motion was 38° (15°-50°). There were no deep infections or septic arthritis. Three ankles had superficial skin necrosis that healed without any additional procedures. One patient had prolonged and substantial swelling of the leg, despite of the routine antithrombotic prophylaxis. Five patients needed their fibular plates removed due to local irritation.

Conclusion: The direct reduction and fixation of the posterior malleolus fractures allow anatomical restoration of the ankle mortise. This is a prerequisite for an optimal functional recovery and appears to be a safe treatment strategy.
Comparative Evaluation of the Content of Antioxidant Polyphenolic Compounds in Selected Bulgarian Medicinal Plants
Authors: Tsanova-Savova S. , Velikov S. , Paneva S. , Koleva P. , Nikolchova P. , Etugov D. , Savova Z. 
Published: April 2022

Abstract
Polyphenols are strong antioxidants of plant origin that exhibit protective role against the development of several chronic degenerative diseases. Quantitative data on the content of polyphenolic antioxidants in Bulgarian medicinal plants are sporadic and unsystematic.

The aim of the study is to determine polyphenols content in series of extracts, infusions and decocts of selected Bulgarian medicinal plants and fruits and to compare their polyphenolic profile.

Materials and Methods: In the present study 18 Bulgarian medicinal plants and fruits have been analyzed for Total Phenolic and Total Flavonoids content, along with HPLC analysis for their level of the individual flavonoids (+)-Catechin, (-)-Epicatechin and Rutin. Comparative evaluation of the content of antioxidant polyphenolic compounds was performed by hierarchical cluster analysis.

The results show that infusions of Hawthorn (Crategus monogyna) flowers have the highest values of Total Phenolic and Total Flavonoids content, forming a separate Cluster in the analysis of the Agglomeration schedule coefficients. Within fruits, data for Total Phenolics and Total Flavonoids content are more homogenic as the cluster analysis shows distribution of 6 elements in a high mean value group. Elderberry (Sambicus nigra) flowers and fruits are the richest source of Rutin in the selected plants studied.

Conclusion: In the present study new data for polyphenolic content in selected Bulgarian medicinal plants and fruits are presented and their degree of similarity in methanolic extracts, infusions and decocts have been assessed in order to provide new data for development of effective antioxidant medicinal plant compositions.
Three Cases of Encephalopathy / Disseminated Encephalomyelitis in SARS-COV-2 Infection
Authors: Metodiev D. , Toshev Y. , Anachkov K. , Sarbyanova N. , Nachev S. 
Published: April 2022

Abstract
Аs many other viral pandemics, the current SARS-CoV-2 is also characterized by nervous system involvement, mainly in elderly patients with comorbidities. Recent scientific reports indicate that involvement of the nervous system is manifested by a variety of clinical symptoms related to the severity and extent of brain damage. Encephalopathy, encephalitis and polyneuritis are among the complications reported in patients with SARSCoV- 2. These complications have been morphologically proven. As an immune-privileged structure, neural tissue is particularly vulnerable to autoimmune attacks. Therefore, various neurological diseases such as MS, Guillain-Barre syndrome, as well as autoimmune encephalitis and psychosis have also been reported in patients with SARS-CoV-2 infection. Herein, we present three cases of patients who died after infection with the SARS-CoV-2 virus. We emphasize on the pathomorphological changes found in a detailed study of the brain and cervical spine. The analysis of the inflammatory findings, mainly manifested by perivenous lymphocytic infiltrates, serodiapedesis and erythrocyte depots around the vessels, showed a presence of initial demyelination (in two of the cases). The blood supply of most venous vessels with different size and a pronounced “sludge” phenomenon were the most impressive findings, as in some sections these changes were demonstrated by a presence of thrombosis. Inflammatory manifestations were also observed in the brainstem near to the stem nuclei. The SARS-CoV-2 virus induces a variety of immune system responses. In some patients there is a negligible or no reaction, while in others there is a “cytokine storm” with a system damage of multiple organs – often including the brain.
Long COVID-19 Syndrome: Multiorgan Damage and Recommendations for Follow-Up and Rehabilitation
Authors: Cherneva R. , Cherneva Zh. 
Published: April 2022

Abstract
The majority of the SARS-CoV-2 infected patients fully recover within a few weeks. However, a significant proportion of them, independently of their age, still have multi-organ damage, similar to that during the acute phase of infection, or symptoms for a longer term afte r recovery. “Postacute-COVID-19 (Long COVID-19 Syndrome)” is a term used for COVID-19 patients who are still symptomatic 4 and 12 weeks after the onset of acute symptoms and “Post-COVID-19-syndrome” ‒ for those with symptoms for longer than 12 weeks after the onset of acute symptoms. The severity of the initial infection does not correlate with the probability for and with the severity of long-term symptoms. This review comments on the multiorgan effects of Long COVID-19 Syndrome: respiratory, cardiovascular, hematological, renal, gastrointestinal, neurological, and metabolic ones. Recommendations for follow-up and rehabilitation for the recovery of Long COVID-19 Syndrome patients are discussed in detail.
Controversy: Critical Review of the Stich Trial and Assessment of Viability. “Back to the Future” Or Maybe Not
Authors: Grigorov V. , Grigorov E. 
Published: April 2022

Abstract
The management of patients with coronary artery disease and heart failure has been debated for years. In the 1980’s Braunwald coined the words “viability” and “stunning”. Multiple trials have been done since then. Since the early eighties coronary bypass grafting was considered as gold standard for patients with impaired left ventricular fraction and coronary artery disease. Since then, nuclear imaging studies have been used to evaluate the “viability” of the impaired areas and to decide if revascularisation would be reasonable. Beginning with the CASS study and ending with the more recent STICH study we aim to provide a “bird’s eye view” of the pros and cons for revascularisation. In addition, we aim to shed some light on the daily advancements in medical management, including devices and not just medication. We therefore chose the title “Back to the future” or maybe not.
Geomorphology of the Beqaa Valley, Lebanon and Anti-Lebanon Mountains
Authors: Lemenkova Polina 
Published: April 2022

Abstract
Geomorphology of Lebanon presents a unique pattern of contrasting landforms. These include two notable mountain ranges, the Lebanon and Anti-Lebanon Mountains, the Beqaa Valley, the elongated coastal area and a significant amount of karst relief forms. This study focuses on the investigation of the topographic and geologic setting of Lebanon by visualizing datasets covering Lebanon and Anti-Lebanon mountains and the Beqaa Valley. Data were collected using the open source repositories of the high-resolution data (GEBCO, ETOPO1, DEM embedded in R). Three 3D models of the relief of the country are presented based on the ‘grdview’ package of GMT with azimuth rotations of the view point at 205°/30° and 165°/30°. The geologic map is based on the compiled datasets of the USGS. The R based modelling allowed division of the raster grid into several geomorphological zones according to the slope steepness and aspect orientation. The extreme elevations of the study area range from -2007 m and 2973 m. The key contribution of this work is the topographic and geologic data synthesis for 2D and 3D modelling of Lebanon. Another aspect concerns technical integration of GMT and R scripting approaches with QGIS mapping into the cartographic framework for visualizing of the Lebanese topography as a multi-tool approach. For the future similar studies on Lebanon this paper can serve as a guide for completing a project on the multi-source 2D and 3D data mapping as a conceptual foundation for research on Lebanese environment.
An ontological model to support citizen science in the field of invasive species research
Authors: Milchev Radoslav , Milchev Galin , Tomov Rumen 
Published: April 2022

Abstract
Advances in information technology developments have led to improved ways and means of sharing information and good practices in various areas of social development. Providing the necessary tools enables Citizen Sciences (CS) to play an important role in raising awareness and engaging various stakeholders in the prevention of invasive alien species (IAS). In Bulgaria, up until this point, it is poorly developed, and this is largely due to the lack of information to the general public regarding the categorization of species, pathways of introduction and their negative impact. The article examines the possibilities for introduction and use of an advanced ontological model in the area of invasive alien species research, which will aid the process of involving a wide range of stakeholders in various initiatives that will contribute to preventing the introduction and spread of IAS. The researched approach using the advantages of modern information and communication technologies includes acquaintance with the basic concepts in the area of IAS, the processes related to their introduction and spread, as well as taking into account the existing interrelationships, which would provide opportunities for early detection and the rapid eradication of IAS. The developed model will also be applied to measures and policies put in place to change the attitudes of the general public to the problem of IAS.
Antimicrobial drug resistance against the background of the COVID-19 pandemic in Bulgaria and Europe: A profound review of the available literature sources
Authors: Mihaylova Yordanka , Stamova Sylvia , Georgieva Emilia , Ermenlieva Neli , Beyti Berna 
Published: April 2022

Abstract
Improper use of antibiotics is an extremely worrying trend worldwide. This leads to the development of resistance to these drugs. As a result, antibiotics stop working and bacteria continue to grow. The highest levels of resistance, both in our country and worldwide, are to second and third-generation cephalosporins, some aminoglycosides, and others. The reason is that these antibiotics have been used most irrationally over the years. The pandemic of COVID-19 and Antimicrobial drug resistance (AMR) are parallel and interrelated serious health situations, between which there is a causal link, manifested in high mortality among the human population. This review highlights relations between growth rates of antimicrobial resistance and the Covid-19 pandemic situations in Bulgaria and Europe in this fast-growing research area.
Short peptide analogs of LfcinB synthesized by Solid Phase Peptide Synthesis as an alternative to global microbial resistance
Authors: Georgieva Dimana Dimitrova 
Published: April 2022

Abstract
Antibiotics are the main therapy in the treatment of infections caused by pathogenic bacteria. Their frequent and prolonged use leads to the development and spread of resistant microorganisms. According to the WHO, there is a worrying increase in global resistance to conventional antimicrobial therapy. This in turn poses a serious risk to public health and requires the search for an alternative to traditional pathogen therapy. Antimicrobial peptides (AMPs) are of great interest in this regard. They are produced naturally in all living organisms and are the first line of defense against fungi, viruses and bacteria. An example ofAMP with proven antimicrobial action are lactoferricins. They are cationic amphipathic peptides and have been found in both humans (LfcinH) and other mammals (cattle (LfcinB), mice (LfcinM) and goats (LfcinC). The most powerful antibacterial effect among them shows LfcinB. Using SPPS methods, short peptide molecules were obtained, analogs of LfcinB, which show a stronger antibacterial effect compared to the native peptide. In recent years, lactoferricins have been the subject of a number of scientific studies and represent a potential alternative for the development of new therapies to combat antimicrobial drug resistance.
Seidenfia manikathila (Orchidaceae, Epidendroideae, Malaxideae), a new species from south Western Ghats, India
Authors: Mathew Jose , Pichan Salim , Madhavan Radhamany , Sarojini Usha Soman , Madhusudhanan Karadka , Szlachetko Dariusz L. 
Published: April 2022

Abstract

Seidenfia manikathila J.Mathew, P.M. Salim & Szlach. (Orchidaceae), a new species from the southern Western Ghats, Kerala, India, is described and illustrated based on morphological data. We demonstrate that the new species differs from other Seidenfia species both in vegetative and floral characters. The diagnostic morphological characters, distribution and images of the new species are presented in this paper. Images and key to the known species of Seidenfia coming under the section Seidenfia from India (S. densiflora, S. intermedia, S. malabarica, S. rheedi, S. versicolor) is also provided.