bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current Knowledge and Future Perspectives of Buttock Augmentation: A Bibliometric Analysis from 1999 to 2021
Authors: Dai Yuxuan , Chen Yu , Hu Yiming , Zhang Lianbo 
Published: October 2022

Abstract
Background
The number of patients undergoing buttock augmentation surgery has increased rapidly with time, changes in people’s aesthetic perceptions, and the increased concern for their shape. The number of publications regarding buttock augmentation has also continued to increase. However, no bibliometric analysis concerning buttock augmentation has been published. This study aimed to provide a qualitative and quantitative evaluation of buttock augmentation-related publications using bibliometric analysis and information on research hotspots and trends in this field.

Methods
The buttock augmentation-related publications published between 1999 and 2021 were extracted from the Web of Science Core Collection (WOSCC) database for analysis. The data were analysed and presented using VOSviewer and Microsoft Excel.

Results
There were 492 articles in the (WOSCC) database, including 442 (89.84%) original research articles, with the number of publications increasing each year. The USA (208 publications, 42.28%) is the leading contributor in this field and has a high academic reputation. The most productive and co-cited journal on this subject is “Plastic and Reconstructive Surgery” (66 publications, 13.41%, 2200 citations). Cardenas-Camarena (9 publications, 1.83%, 158 citations) was the most published and co-cited author. Research hotspots include the following three topics: experience and technology of buttock augmentation, autologous fat buttock augmentation and its safety, and buttock aesthetics study. There will be more publications in the future, and research trends will focus on silicone implants, safety, satisfaction, and autologous fat grafting.

Conclusion
Buttock augmentation research is rapidly evolving, and this study provides a perspective view of buttock augmentation research in Plastic and Reconstructive Surgery.

Level of Evidence III
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
The Decrease in Serum sRAGE Levels Upon Smoking is Associated with Activated Neutrophils
Authors: Wiersma Valerie R. , Hoonhorst Susan J. M. , ten Hacken Nick H. T. , van den Berge Maarten , Slebos Dirk-Jan , Pouwels Simon D. 
Published: October 2022

AbstractThe serum level of the soluble Receptor for Advanced Glycation End-products (sRAGE) is a promising blood biomarker for the development, severity, and progression of chronic obstructive pulmonary disease (COPD). However, cigarette smoking causes a nearly instant drop in circulating sRAGE levels, strongly impacting on the variability in sRAGE levels. In the current study, we investigated the possible mechanism behind the sudden drop in sRAGE upon smoking. We showed that the number of activated neutrophils in blood significantly increases within two hours upon smoking three cigarettes within one hour. Furthermore, an increased expression of the leukocyte activation marker CD11b, which is a known ligand for RAGE, was observed upon smoking. Additionally, the in vitro activation of neutrophils increased their capacity to bind sRAGE. Together, these data indicate that smoking activates neutrophils in the circulation with concomitant upregulation of the RAGE ligand CD11b, leading to reduced levels of sRAGE in serum.
The prediction method for standard enthalpies of apatites using the molar volume, lattice energy, and linear correlations from existing experimental data
Authors: Puzio Bartosz , Manecki Maciej 
Published: October 2022

AbstractExperimental data of thermodynamic state functions and molar volume for phosphate, arsenate, and vanadate apatites containing Ca, Sr, Ba, Pb, end Cd at the cationic positions Me2+ and F, OH, Cl, Br, and I at the halide position X were collected. The apatite supergroup splits into distinct subgroups (populations) constituted by Me10(AO4)6X2 with the same Me2+ cations and tetrahedral AO43− anions but with different anions at the X position. Linear relationships between various parameters within apatite subgroups are observed. The prediction method for standard enthalpies of apatites (ΔHºf,el) is based on regression analysis of the linear correlations within the subgroups between ΔH°f,el of apatites and their molar volume Vm, lattice energy UPOT, and ΔH°f,el of their anions AO43− or X−. This allowed to predict 22 new ΔH°f,el values for apatites and materials with an apatite structure. The prediction precision is comparable to the experimental uncertainty obtained when reproducing experimental data using calorimetric measurements or dissolution experiments and can be applied to a wider range of apatites than other methods.
No effect of repeated post-resistance exercise cold or hot water immersion on in-season body composition and performance responses in academy rugby players: a randomised controlled cross-over design
Authors: Horgan Barry G. , Halson Shona L. , Drinkwater Eric J. , West Nicholas P. , Tee Nicolin , Alcock Rebekah D. , Chapman Dale W. , Haff G. Gregory 
Published: October 2022

Abstract
Purpose

Following resistance exercise, uncertainty exists as to whether the regular application of cold water immersion attenuates lean muscle mass increases in athletes. The effects of repeated post-resistance exercise cold versus hot water immersion on body composition and neuromuscular jump performance responses in athletes were investigated.

Methods

Male, academy Super Rugby players (n = 18, 19.9 ± 1.5 y, 1.85 ± 0.06 m, 98.3 ± 10.7 kg) participated in a 12-week (4-week × 3-intervention, i.e., control [CON], cold [CWI] or hot [HWI] water immersion) resistance exercise programme, utilising a randomised cross-over pre–post-design. Body composition measures were collected using dual-energy X-ray absorptiometry prior to commencement and every fourth week thereafter. Neuromuscular squat (SJ) and counter-movement jump (CMJ) performance were measured weekly. Linear mixed-effects models were used to analyse main (treatment, time) and interaction effects.

Results

There were no changes in lean (p = 0.960) nor fat mass (p = 0.801) between interventions. CON (p = 0.004) and CWI (p = 0.003) increased (g = 0.08–0.19) SJ height, compared to HWI. There were no changes in CMJ height (p = 0.482) between interventions.

Conclusion
Repeated post-resistance exercise whole-body CWI or HWI does not attenuate (nor promote) increases in lean muscle mass in athletes. Post-resistance exercise CON or CWI results in trivial increases in SJ height, compared to HWI. During an in-season competition phase, our data support the continued use of post-resistance exercise whole-body CWI by athletes as a recovery strategy which does not attenuate body composition increases in lean muscle mass, while promoting trivial increases in neuromuscular concentric-only squat jump performance.
Testicular microlithiasis in paediatric patients with Klinefelter syndrome from infancy till adolescence: early start of degenerative process in the testes—preliminary results
Authors: Januś Dominika , Wójcik Małgorzata , Starzyk Jerzy B. 
Published: October 2022

AbstractTo present the results of testicular ultrasonography supported by clinical and hormonal aspects in paediatric patients with Klinefelter syndrome (KS). Prospective analysis of medical files of 20 patients diagnosed with KS between 2016 and 2022. Assessed data included analysis of causes of referral, ultrasound, and clinical characterisation with hormonal evaluation of serum FSH, LH, testosterone, inhibin B, and anti-Müllerian hormone. Non-mosaic Klinefelter syndrome (47, XXY) was diagnosed in 65% of cases (13/20) by the geneticist (including 7 cases prenatally), in 25% (5/20) by the endocrinologist and in 10% (2/20) by the hematologist. Ultrasound assessment revealed bilateral testicular microlithiasis (TM) in all patients. The youngest KS patient with TM was 3 months old. TM patterns have not changed during follow-ups of up to 6 years in any of the patients. In all KS patients markedly reduced echogenicity and in pubertal KS patients, also irregular echostructure of the testes was observed. The hormonal patterns observed in the study group were typical for those already described in KS. Sertoli and Leydig cell function was intact in prepubertal patients and deteriorated after the start of puberty.Conclusion: Although the degenerative process in the testicular tissue starts very early in the testes in KS and is reflected in morphological changes seen in ultrasonography, Sertoli and Leydig cell hormonal function is normal in prepubertal KS patients.

What is Known:• So far, normal Leydig and Sertoli cell function was observed in infants and prepubertal KS patients.

What is New:• The morphological changes in the testes in KS may already be seen in early infancy.
Benefits of supportive strategies for carers of people with high-grade glioma: a systematic review
Authors: Jones Diana , Pinkham Mark B. , Wallen Matthew P. , Hart Nicolas H. , Joseph Ria , Strodl Esben , Ownsworth Tamara , Beesley Vanessa , Crichton Megan , Chan Raymond J. 
Published: October 2022

Abstract

Purpose
To systematically review and examine current evidence for the carer-reported benefits of supportive care strategies for carers of adults with high-grade glioma (HGG).

Methods
Four databases (CINAHL, EMBASE, PubMed, PsycINFO) were searched for articles published between January 2005 and April 2022 that assessed strategies for addressing the supportive care needs of carers of adults with HGG (WHO grade 3–4). Study selection and critical appraisal were conducted independently by three authors (DJ/MC, 2021; DJ/RJ 2022). Data extraction was conducted by one author (DJ) and checked by a second author (RJ). Results were synthesised narratively.

Results
Twenty-one studies involving 1377 caregivers were included, targeting the carer directly (n = 10), the patient-carer dyad (n = 3), or focused on people with HGG + / − their carers (n = 8). A paucity of high-quality evidence exists for effective and comprehensive support directly addressing outcomes for carers of adults with HGG. Strategies that demonstrated some benefits included those that built carer knowledge or provided emotional support, delivered by health professionals or through peer support. Supportive and early palliative care programmes have potential to reduce unmet carer needs while providing ongoing carer support.

Conclusion
Strategies incorporating an educational component, emotional support, and a regular needs assessment with corresponding tailored support are most valued by carers. Future practice development research should adopt a value-based approach and exceed evaluation of efficacy outcomes to incorporate evaluation of the experience of patients, carers, and staff, as well as costs.
Intrinsic subtypes in Ethiopian breast cancer patient
Authors: Desalegn Zelalem , Yohannes Meron , Porsch Martin , Stückrath Kathrin , Anberber Endale , Santos Pablo , Bauer Marcus , Addissie Adamu , Bekuretsion Yonas , Assefa Mathewos , Worku Yasin , Taylor Lesley , Abebe Tamrat , Kantelhardt Eva Johanna , Vetter Martina 
Published: October 2022

Abstract
Purpose
The recent development of multi-gene assays for gene expression profiling has contributed significantly to the understanding of the clinically and biologically heterogeneous breast cancer (BC) disease. PAM50 is one of these assays used to stratify BC patients and individualize treatment. The present study was conducted to characterize PAM50-based intrinsic subtypes among Ethiopian BC patients.

Patients and methods
Formalin-fixed paraffin-embedded tissues were collected from 334 BC patients who attended five different Ethiopian health facilities. All samples were assessed using the PAM50 algorithm for intrinsic subtyping.

Results
The tumor samples were classified into PAM50 intrinsic subtypes as follows: 104 samples (31.1%) were luminal A, 91 samples (27.2%) were luminal B, 62 samples (18.6%) were HER2-enriched and 77 samples (23.1%) were basal-like. The intrinsic subtypes were found to be associated with clinical and histopathological parameters such as steroid hormone receptor status, HER2 status, Ki-67 proliferation index and tumor differentiation, but not with age, tumor size or histological type. An immunohistochemistry-based classification of tumors (IHC groups) was found to correlate with intrinsic subtypes.

Conclusion
The distribution of the intrinsic subtypes confirms previous immunohistochemistry-based studies from Ethiopia showing potentially endocrine-sensitive tumors in more than half of the patients. Health workers in primary or secondary level health care facilities can be trained to offer endocrine therapy to improve breast cancer care. Additionally, the findings indicate that PAM50-based classification offers a robust method for the molecular classification of tumors in the Ethiopian context.
Disease threshold-based fungicide applications: potential of multi-disease resistance in winter wheat cultivars in Germany
Authors: Klocke Bettina , Sommerfeldt Nicole , Wagner Christina , Schwarz Jürgen , Baumecker Michael , Ellmer Frank , Jacobi Andreas , Matschiner Katja , Petersen Jan , Wehling Peter , Sellmann Jörg , Rajmis Sandra , Kehlenbeck Hella 
Published: October 2022

AbstractThe presence of foliar pathogens often leads to yield losses in winter wheat (Triticum aestivum L.), the most important crop in Germany. In this study the efficacy of different host resistance levels of eight wheat cultivars and three fungicide strategies on fungal disease control was studied in terms of yield and net return in field trials at five sites over three crop years. Fungicide treatments included a situation-related strategy in which cultivars were treated individually based on disease control thresholds, a practice-related strategy in which all cultivars were treated after disease thresholds had been exceeded in one cultivar, and an untreated control. Disease severity and incidence differed between cultivars and were reduced by fungicide treatments compared to the untreated control. On average over all locations and years, the Fungicide Treatment Frequency Index (TFI) of all cultivars treated with the situation-related strategy was significantly lower than those treated with the practice-related strategy, except the highly susceptible cultivar JB Asano. A reduction of the TFI by up to 82% was possible in the situation-related strategy. Despite slightly increased yields in the practice-related strategy compared to the situation-related strategy, these could not compensate for the higher fungicide costs in most cases and led to lower net returns. The cultivars with multi-disease resistance showed clear advantages. Their potential benefits are not only demonstrated by the attainment of high yields, but also in fungicide savings without reducing net returns, provided that their disease resistance characteristics are taken into account.
Simple numerical solutions to the Einstein constraints on various three-manifolds
Authors: Zhang Fan , Lindblom Lee 
Published: October 2022

AbstractNumerical solutions to the Einstein constraint equations are constructed on a selection of compact orientable three-dimensional manifolds with non-trivial topologies. A simple constant mean curvature solution and a somewhat more complicated non-constant mean curvature solution are computed on example manifolds from three of the eight Thursten geometrization classes. The constant mean curvature solutions found here are also solutions to the Yamabe problem that transforms a geometry into one with constant scalar curvature.
Alleviation of drought and salt stress in vegetables: crop responses and mitigation strategies
Authors: Khalid Muhammad Fasih , Huda Samsul , Yong Miingtiem , Li Lihua , Li Li , Chen Zhong-Hua , Ahmed Talaat 
Published: October 2022

AbstractIn recent decades, the demand for vegetables has increased significantly due to the blooming global population. Climate change has affected vegetable production by increasing the frequencies and severity of abiotic and biotic stresses. Among the abiotic stresses, drought and salinity are the major issues that possess severe threats on vegetable production. Many vegetables (e.g., carrot, tomato, okra, pea, eggplant, lettuce, potato) are usually sensitive to drought and salt stress. The defence mechanisms of plants against salt and drought stress have been extensively studied in model plant species and field crops. Better understanding of the mechanisms of susceptibility of vegetables to drought and salt stresses will help towards the development of more tolerant genotypes as a long-term strategy against these stresses. However, the intensity of the challenges also warrants more immediate approaches to mitigate these stresses and enhance vegetable production in the short term. Therefore, this review enlightens the updated knowledge of responses (physiological and molecular) against drought and salinity in vegetables and potentially effective strategies to enhance production. Moreover, we summarized different technologies such as seed priming, genetic transformation, biostimulants, nanotechnology, and cultural practices adopted to enhance vegetable production under drought and salinity stress. We propose that approaches of conventional breeding, genetic engineering, and crop management should be combined to generate drought and salt resistance cultivars and adopt smart cultivation practices for sustainable vegetable production in a changing climate.
Association between sodium-glucose cotransporter-2 inhibitors and incident atrial fibrillation/atrial flutter in heart failure patients with reduced ejection fraction: a meta-analysis of randomized controlled trials
Authors: Sfairopoulos Dimitrios , Liu Tong , Zhang Nan , Tse Gary , Bazoukis George , Letsas Konstantinos , Goudis Christos , Milionis Haralampos , Vrettos Apostolos , Korantzopoulos Panagiotis 
Published: October 2022

Abstract
Atrial fibrillation (AF) and atrial flutter (AFL) are associated with adverse outcomes in patients with heart failure and reduced ejection fraction (HFrEF). We investigated the effects of sodium-glucose cotransporter-2 inhibitors (SGLT2i) on the incidence of AF and/or AFL in HFrEF patients. PubMed and ClinicalTrials.gov were systematically searched until March 2022 for randomized controlled trials (RCTs) that enrolled patients with HFrEF. A total of six RCTs with 9467 patients were included (N = 4731 in the SGLT2i arms; N = 4736 in the placebo arms). Compared to placebo, SGLT2i treatment was associated with a significant reduction in the risk of AF [relative risk (RR) 0.62, 95% confidence interval CI 0.44–0.86; P = 0.005] and AF/AFL (RR 0.64, 95% CI 0.47–0.87; P = 0.004). Subgroup analysis showed that empagliflozin use resulted in a significant reduction in the risk of AF (RR 0.55, 95% CI 0.34–0.89; P = 0.01) and AF/AFL (RR 0.50, 95% CI 0.32–0.77; P = 0.002). By contrast, dapagliflozin use was not associated with a significant reduction in the risk of AF (RR 0.69, 95% CI 0.43–1.11; P = 0.12) or AF/AFL (RR 0.82, 95% CI 0.53–1.27; P = 0.38). Additionally, a “shorter” duration (< 1.5 years) of treatment with SGLT2i remained associated with a reduction in the risk of AF (< 1.5 years; RR 0.58, 95% CI 0.36–0.91; P = 0.02) and AF/AFL (< 1.5 years; RR 0.52, 95% CI 0.34–0.80; P = 0.003). In conclusion, SGLT2i therapy was associated with a significant reduction in the risk of AF and AF/AFL in patients with HFrEF. These results reinforce the value of using SGLT2i in this setting.
Right ventriculography improves the accuracy of leadless pacemaker implantation in right ventricular mid-septum
Authors: Li Yaodong , Xing Qiang , Xiaokereti Jiasuoer , Chen Cheng , Zhang Jianghua , Zhou Xianhui , Lu Yanmei , Tuerhong Zukela , Tang Baopeng 
Published: October 2022

Abstract

Background
Implanting leadless pacemakers in the right ventricular (RV) apex is prone to causing pericardial tamponade and myocardial perforation.

Objective
To investigate the feasibility and safety of right ventriculography-guided implantation of Micra™ leadless pacemaker (Micra™, Medtronic, Minneapolis, MN, USA) in the RV mid-septum.

Methods
One hundred eight consecutive patients who underwent Micra™ implantation intended in the mid-septum were enrolled and randomized (3:1) into the radiography group (n = 81) with assistance of right ventriculography to illustrate the RV septum and the non-radiography group (n = 27). All subjects underwent a postoperative computed tomography (CT) scan to determine the Micra™ location. The Micra™ location assessed by CT image was compared between the two groups to confirm the accuracy of the intended pacing site. The duration of the procedure, X-ray radiation dose, and time were also compared between the two groups.

Results
Reconstructed CT 3-D cardiac images found the Micra™ location in the intended mid-septum in 13 patients (48.1%, 13/27) in the non-radiography group and 76 patients (93.8%, 76/81) in the radiography group (P < 0.0001 between two groups). There was no significant difference in procedure interval between the two groups while the X-ray radiation dose (564.86 ± 112.44 vs. 825.85 ± 156.12 mGy, P < 0.0001), X-ray exposure time (7.79 ± 1.43 vs. 12.03 ± 2.86 min, P < 0.0001), and the number of fluoroscopy re-positioning (2.79 ± 1.03 vs. 6.41 ± 1.82, P < 0.0001) were significantly less in the radiography group than in the non-radiography group. No implantation-related complications were observed in both groups.

Conclusion
Right ventriculography increases the accuracy of Micra™ implantation in the mid-septum and reduces X-ray exposure.

Trial registration
The trial registration number (ChiCTR2100051374) and date (09/22/2021).
The k0-INRIM software version 2.0: presentation and an analysis vademecum
Authors: Di Luzio Marco , D’Agostino Giancarlo 
Published: October 2022

AbstractThe k0-INRIM software was developed at INRIM to perform k0-standardization Neutron Activation Analysis and evaluate combined uncertainty through application of the spreadsheet method. However, the presence of some limitation made its use, as a tool for routine NAA, impractical. With the aim to participate to the 2021 IAEA k0-NAA software intercomparison to evaluate the effect on mass fraction results due to software used, the k0-INRIM was sizably updated in order to meet the agreed functionality requirements to take part to the exercise. In this work, the version 2.0 of the software is presented and a point-by-point example analysis is displayed. The software version here described is available for download together with the corresponding updated user’s manual.