bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors of a severe course of pediatric multi-system inflammatory syndrome temporally associated with COVID-19
Authors: Stasiak Aleksandra , Perdas Ewelina , Smolewska Elżbieta 
Published: August 2022

AbstractPediatric multi-system inflammatory syndrome temporally associated with COVID-19 (PIMS-TS) is a serious complication of a previous SARS-CoV-2 infection. The disease causes multiple organ failure, but in some patients, a more severe course of the disease is observed. The treatment is multidirectional and depends on the severity and course of the disease, as some patients do not respond to the recommended treatment. The aim of this study was to identify laboratory risk factors affecting the more severe course of the disease and resistance to standard therapy. It is a single-center retrospective study considering 51 patients with PIMS-TS. Clinical features, laboratory results, and additional imaging tests data were taken into account. Fifty-one patients with PIMS-TS were hospitalized within a 16-month observation period. In the studied group, 26/51 children (51%) were girls. The mean age of patients was 7 years. Sex of the patient was not a risk factor for changes in cardiovascular system or severe course of the disease. Sixteen patients (31.3%) required transfer to the intensive care unit. Children with initially higher concentrations of NT-proBNP, troponin, creatinine, triglycerides, C-reactive protein, procalcitonin, ferritin, D-dimers and lower hematocrit, platelet count, lymphocytes, and ejection fraction should be strictly observed as they have a higher risk of severe course of the disease.Conclusions: Laboratory parameters especially markers of myocardial damage, markers of inflammation, blood count, as wells as biochemical parameters are significant risk indicators of severe course of PIMS -TS and their concentration can be defined as predictor of disease severity.

What is Known:• Pediatric multisystem inflammatory syndrome temporally associated with COVID-19 (PIMS-TS) is a serious complication of a previous SARS-CoV-2 infection in the group of pediatric patients• Course of the disease may be severe, which may cause long-term complications and the need for longitudinal patient care.

What is New:• Children with higher concentrations of NT-proBNP, troponin, creatinine, TG, CRP, PCT, ferritin, D-dimers and lower hematocrit, PLT, lymphocytes, and EF have a higher risk of a severe course of the disease.• Patients with high concentration of NT-proBNP, troponin, CRP, lactates, ferritin, D-dimers, creatinine and a lower concentration of PLT, albumin, leukocytes; lymphopenia, hyponatremia are at risk for intravenous immunoglobulin resistance.
Was tun mit urbanen Gewässern? Evaluierung des ökologischen Nutzens am Wienfluss mittels Habitatmodellierung
Authors: Gruber Gabriel , Hayes Daniel S. , Lett Amélie , Zeiringer Bernhard , Pinter Kurt 
Published: August 2022

ZusammenfassungEin offenes Kontinuum in Fließgewässern ist zentral für den Lebenszyklus vieler Wanderfischarten wie der Barbe (Barbus barbus) oder der Nase (Chondrostoma nasus). Obwohl bereits mehrere Jahre an der Passierbarkeit gearbeitet wird, ist derzeit die Durchgängigkeit bei etwa der Hälfte der österreichischen Wasserkörper immer noch eingeschränkt. Fließgewässer, welche durch städtischen Raum fließen, weisen zudem oft über lange Strecken starke anthropogene Beeinträchtigungen und daher eine geringe Lebensraumqualität auf. Der Wienfluss ist ein Beispiel für ein Gewässer, welches abschnittsweise eine potenziell gute Habitatausstattung für die Donaufischfauna aufweist, im Unterlauf jedoch von Querbauwerken fragmentiert ist und über mehrere Kilometer in einem Betongerinne fließt. In der vorliegenden Arbeit wird der Frage nachgegangen, ob die Wiederanbindung eines urbanen Gewässers wie dem Wienfluss für ein Flusssystem wie das der Donau einen ökologischen Nutzen bringen kann. Dazu erstellten wir drei hydro-dynamische Habitatmodelle flussauf des stark regulierten Unterlaufs. Mittels Präferenzkurven von Barben und Nasen unterschiedlicher Alters- und Lebensstadien – (i) Larve, (ii) Juvenil, (iii) Adult im Sommerhabitat, (iv) Adult im Laichhabitat – wurde die Habitateignung jedes Abschnitts für typische Abflüsse analysiert. Die Ergebnisse zeigen, dass alle Strecken geeignete Habitate für Larven- und Juvenilstadien beider Fischarten aufweisen. Adult- und Laichhabitate sind hingegen nur eingeschränkt vorhanden; die höchste Nutzung ist bei Abflüssen um Mittelwasser zu erwarten. Zusammenfassend bietet die Wiederanbindung die Möglichkeit, dass die oberen Abschnitte für die Reproduktion und die Entwicklung der Jungfische geeignet sind. In Folge ist von einer positiven Strahlwirkung auf die Populationen der Donau auszugehen. Eine Ausschöpfung des Revitalisierungspotenzials würde sich zusätzlich positiv auf andere Aspekte wie den Erholungswert, die Landschaftsästhetik, das Städteklima und auf die Fischerei auswirken.
Multiple dimensions of radiographic reconstruction for the optimal operative strategy of sacral meningeal cysts
Authors: Ma Qianquan , Xie Jingcheng , Yang Chenlong , Wu Chao , Zhang Jia , Yin Xiaoliang , Si Yu , Liu Ying , Yang Jun , Sun Jianjun 
Published: August 2022

Abstract
Background and purpose
The contents and subtypes of sacral cysts are sophisticated in many cases. We applied multiple dimensional magnetic resonance imaging (MRI) reconstruction to preoperatively clarify the specific subtype of sacral meningeal cysts.

Materials and methods
We preoperatively used multimodal neural reconstruction MRI sequences to evaluate 76 patients with sacral cysts. The linear nerve roots were precisely traced based on sagittal or coronal images processed at various angles and levels which was conducive to the design of the operation strategy.

Results
Cysts with nerve passage were detected in 47 cases (62%, 47/76), whereas cysts without nerve roots were detected in 24 cases (32%, 24/76). Five patients had mixed cysts with or without nerve roots. Intraoperative exploration results proved the high accuracy of image reconstruction; only one cyst without a nerve root was misdiagnosed prior to surgery.

Conclusion
MRI reconstruction based on the three-dimensional fast imaging employing steady-state acquisition T2 sequence precisely tracked the nerve roots of sacral cysts and guided the optimal strategy during surgery.
Preferences for attributes of long-term care in dementia: a scoping review of multi-criteria decision analyses
Authors: Speckemeier Christian 
Published: August 2022

Abstract
Aim
Long-term care considerations for persons with dementia are complex. Multi-criteria decision analysis (MCDA) methods are increasingly used to support healthcare decisions. The objective of this scoping review was to identify and analyze published MCDAs in which preferences for living and care concepts for persons with dementia are determined.

Subject and methods
A literature search was conducted in PubMed, EMBASE, Web of Science, and Google Scholar in October 2021. Searches were limited to peer-reviewed articles published up to October 14, 2021. The included publications aimed at eliciting care preferences for persons with dementia from patients, relatives, healthcare practitioners or the broader public by means of MCDA.

Results
Ten studies were included of whom seven were published in 2017 or afterwards. In nine studies, a discrete choice experiment (DCE) was conducted. The majority of studies surveyed the general population or caregivers of persons with dementia. Five studies assessed preferences for attributes of home care and two for long-term care facilities. Willingness to pay was addressed in eight studies. Choice task structure and experimental design varied widely. Despite different objectives, strong preferences for continuous care by the same person, organizational aspects, and caregiver expertise were found across studies.

Conclusion
This review shows that MCDA methods have successfully been applied to analyze preferences for living and care arrangements for persons with dementia. The majority of publications report on DCEs, and a variety of different study objectives and methodological approaches have been observed. Further research is needed to inform the design of innovative concepts which are a valuable alternative to existing care options.
Measures, Gaps, and Mitigation Strategies in Bangladesh’s COVID-19 Response
Authors: Al Sattar Abdullah , Irin Nusrat , Belgrad Joseph P. , Haider Najmul , Chisty Nurun Nahar , Mohsin Md. Abu Shoieb , Foysal Mohammad , Das Tridip , Uddin Md. Helal , Hasan Rubyath Binte , Ferdous Jinnat , Hasan Mahmudul , Mahmud Rashed , Samad Mohammed Abdus , Giasuddin Mohammad , Biswas Paritosh Kumar , Pfeiffer Dirk Udo , Debnath Nitish Chandra , Fournié Guillaume , Tomley Fiona M. , Hoque Md. Ahasanul 
Published: August 2022

AbstractThe Coronavirus Disease 2019 (COVID-19) spread rapidly from China to most other countries around the world in early 2020 killing millions of people. To prevent virus spread, world governments implemented a variety of response measures. This paper’s objectives were to discuss the country’s adopted measures to combat the virus through June 2020, identify gaps in the measures’ effectiveness, and offer possible mitigations to those gaps. The measures taken included screening device deployment across international air and land ports, flight suspensions and closures from COVID-19 affected countries, and declaration and extension of a national public holiday (equivalent to lockdowns in other countries). Identified gaps were test kit, PPE, ICU beds, and ventilator shortages, limited public awareness, and insufficient coordination and collaboration among national and international partners. Proper and timely risk mapping, preparedness, communication, coordination, and collaboration among governments and organizations, and public awareness and engagement would have provided sufficient COVID-19 mitigation in Bangladesh.
Shortest path with acceleration constraints: complexity and approximation algorithms
Authors: Ardizzoni S. , Consolini L. , Laurini M. , Locatelli M. 
Published: August 2022

AbstractWe introduce a variant of the Shortest Path Problem (SPP), in which we impose additional constraints on the acceleration over the arcs, and call it Bounded Acceleration SPP (BASP). This variant is inspired by an industrial application: a vehicle needs to travel from its current position to a target one in minimum-time, following pre-defined geometric paths connecting positions within a facility, while satisfying some speed and acceleration constraints depending on the vehicle position along the currently traveled path. We characterize the complexity of BASP, proving its NP-hardness. We also show that, under additional hypotheses on problem data, the problem admits a pseudo-polynomial time-complexity algorithm. Moreover, we present an approximation algorithm with polynomial time-complexity with respect to the data of the original problem and the inverse of the approximation factor $$\epsilon$$
ϵ
. Finally, we present some computational experiments to evaluate the performance of the proposed approximation algorithm.
A generalized shortest path tour problem with time windows
Authors: Di Puglia Pugliese L. , Ferone D. , Festa P. , Guerriero F. 
Published: August 2022

AbstractThis paper studies a generalization of the shortest path tour problem with time windows (GSPTPTW). The aim is to find a single-origin single-destination shortest path, which has to pass through an ordered sequence of not necessarily disjoint node-subsets. Each node has a time window for each node-subset to which it belongs. We investigate the theoretical properties of GSPTPTW and propose a dynamic programming approach to solve it. Numerical results collected on a large set of new benchmark instances highlight the effectiveness of the proposed solution approach.
The impact of the mountain barrier on the spread of heavy metal pollution on the example of Gorce Mountains, Southern Poland
Authors: Miśkowiec Paweł 
Published: August 2022

AbstractThe main objective of this study was to determine the content, mobility, and the variability of concentration of zinc, lead, and cadmium in soils from the Gorce Mountains (south Poland), located over 100 km south-east from the potential industrial sources of contamination—zinc-lead sulfide ore mine and smelter in Bukowno, as well as hard coal mines of Silesia region and Kraków Nowa-Huta steelwork. The abovementioned problem is crucial in the context of the traditional mountain farming still extant in the region, as well as intensively developing tourism. The geoaccumulation index and potential ecological risk index were adopted to evaluate soil pollution in the study area and the BCR sequential extraction technique to assess mobility of the abovementioned elements. The obtained results clearly show that the pollution from distant industrial sources in the mountains is detectable. Apart from the increased concentrations of the tested metals in the soil (especially available forms), there is also a strong correlation between the concentrations of lead, zinc, and cadmium, which proves their common source of origin. The main evidence is the fact that differences in the concentrations of the tested metals on the windward and leeward sides were statistically significant. This also means that the studied mountain area, despite relatively low altitudes (up to 1310 m above sea level), constitutes a measurable barrier to the spread of atmospheric pollutants.
Story points changes in agile iterative development
Authors: Pasuksmit Jirat , Thongtanunam Patanamon , Karunasekera Shanika 
Published: August 2022

AbstractStory Points (SP) are an effort unit that is used to represent the relative effort of a work item. In Agile software development, SP allows a development team to estimate their delivery capacity and facilitate the sprint planning activities. Although Agile embraces changes, SP changes after the sprint planning may negatively impact the sprint plan. To minimize the impact, there is a need to better understand the SP changes and an automated approach to predict the SP changes. Hence, to better understand the SP changes, we examine the prevalence, accuracy, and impact of information changes on SP changes. Through the analyses based on 19,349 work items spread across seven open-source projects, we find that on average, 10% of the work items have SP changes. These work items typically have SP value increased by 58%-100% relative to the initial SP value when they were assigned to a sprint. We also find that the unchanged SP reflect the development time better than the changed SP. Our qualitative analysis shows that the work items with changed SP often have the information changes relating to updating the scope of work. Our empirical results suggest that SP and the scope of work should be reviewed prior or during sprint planning to achieve a reliable sprint plan. Yet, it could be a tedious task to review all work items in the product (or sprint) backlog. Therefore, we develop a classifier to predict whether a work item will have SP changes after being assigned to a sprint. Our classifier achieves an AUC of 0.69-0.8, which is significantly better than the baselines. Our results suggest that to better manage and prepare for the unreliability in SP estimation, the team can leverage our insights and the classifier during the sprint planning. To facilitate future studies, we provide the replication package and the datasets, which are available online.
Screening for Autism Spectrum Condition Through Inner City Homeless Services in the Republic of Ireland
Authors: Boilson A. M. , Churchard A. , Connolly M. , Casey B. , Sweeney M. R. 
Published: August 2022

AbstractHomeless service users were screened for autism spectrum disorder through one of Ireland’s leading not for profit service providers. Keyworkers acted as proxy informants; their caseloads were screened using the DSM-5—Autistic Traits in the Homeless Interview (DATHI). Client current and historical health and behaviour data was collated. A representative sample of 106 eligible keyworkers caseloads were screened, identifying 3% “present” and 9% “possibly present” for autistic traits with the DATHI. These findings suggest a high estimate of autism prevalence and support emerging evidence that, people with autism are overrepresented in the homeless population, compared to housed populations. Autism may be a risk factor for entry into homelessness and a challenge to exiting homeless and engaging with relevant services.
Understanding the Use of the Term “Weaponized Autism” in An Alt-Right Social Media Platform
Authors: Welch Christie , Senman Lili , Loftin Rachel , Picciolini Christian , Robison John , Westphal Alexander , Perry Barbara , Nguyen Jenny , Jachyra Patrick , Stevenson Suzanne , Aggarwal Jai , Wijekoon Sachindri , Baron-Cohen Simon , Penner Melanie 
Published: August 2022

Abstract
Background
The term “weaponized autism” is frequently used on extremist platforms. To better understand this, we conducted a discourse analysis of posts on Gab, an alt-right social media platform.

Methods
We analyzed 711 posts spanning 2018–2019 and filtered for variations on the term “weaponized autism”.

Results
This term is used mainly by non-autistic Gab users. It refers to exploitation of perceived talents and vulnerabilities of “Weaponized autists”, described as all-powerful masters-of-technology who are devoid of social skills.

Conclusions
The term “weaponized autism” is simultaneously glorified and derogatory. For some autistic people, the partial acceptance offered within this community may be preferable to lack of acceptance offered in society, which speaks to improving societal acceptance as a prevention effort.
Adolescent Parents’ Intersecting Identities and Experiences: A Qualitative Examination of Adolescents’, Grandparents’, and School Staff’s Perspectives
Authors: Perez-Brena Norma J. , Anders Kristin M. , Toews Michelle L. , Duncan Jeneé C. 
Published: August 2022

AbstractThis study aimed to identify the multiple and intersecting identities adolescent parents manage, and the social supports and constraints that inform their adjustment. Adolescents (n = 13; 70% cisgender women; 100% Latinx; Mage = 19.37, SD = 0.92) who became parents between the ages of 14–18, their parents (n = 17; 82% cisgender women; 94% Latinx), and school staff (n = 7; 100% cisgender women; 71% White) provided triangulating information on adolescent parents’ experiences. Using focus group methodology and Qual-to-Qual coding techniques, we found that adolescents inhabit intersecting social identities based on their parenting status, adolescence/youth, student role, child/family role, and gender. These intersecting social identities informed the social and developmental contexts that adolescents navigated, which were experienced as promotive or inhibiting environments. Adolescents described the demands to be engaged in multigenerational familial contexts (e.g., large coparenting teams, power differentials between adolescents and their parents), their exposure to stereotypes, assumptions, and discrimination based on their intersecting identities, and the high social demands/resources imposed on them by family and school supports. These experiences led to contextualized outcomes, such as an increase in growth and maturity. The participants often described their experiences as both stressors and sources of support; therefore, we discuss the duality of these experiences and the implications for future interventions.
Child Language Brokering in Healthcare: Exploring the Intersection of Power and Age in Mediation Practices
Authors: Iqbal Humera , Crafter Sarah 
Published: August 2022

AbstractThis paper aims to explore young people’s perspectives of a real-life scenario of child language brokering in a healthcare setting (the doctor’s office), when the topic of discussion is sensitive and potentially conflictual. Child Language brokers are migrant young people who translate and interpret for family members, peers and the local community. Often the spaces in which children broker (e.g., healthcare, banks), referred to here as a ‘contact zone’, are dominated by adults in positions of authority and unequal power differentials. The language broker and those for whom they are brokering may be in a less powerful position because of their migration status and/or age status. Existing research has focused mainly from the view of adults and young people’s perspectives on the practice are underexplored. We draw the existing literature to explore how brokers understand the wider societal context and the strategies they employ to manage conflict. Findings are presented from 29 individual qualitative vignette-based interviews with language brokers (aged 13–16) in the United Kingdom which were qualitatively analysed. Findings show how these children play a vital role in protecting those for whom they broker, often navigating sophisticated social interactions and tactics (such as delay and selective modification). Equally, they carry a weight of responsibility trying to manage complicated, perhaps morally questionable, situations. By asking brokers to reflect on a real-life healthcare scenario, we are advancing understanding of migrant youth brokers and the families they support in their day to day lives.
Steerable sheath visualizable under 3D electroanatomical mapping facilitates paroxysmal atrial fibrillation ablation with minimal fluoroscopy
Authors: Rajendra Anil , Hunter Tina D. , Morales Gustavo X. , Zei Paul , Boo Lee Ming , Varley Allyson , Osorio Jose 
Published: August 2022

Abstract
Background
Advances in technology and workflows have facilitated substantial reductions in fluoroscopy utilization and procedure times for atrial fibrillation (AF) ablations. A recently available steerable sheath, visualizable on a 3D electroanatomical map (EAM), may further simplify low/zero fluoroscopy ablation workflows by facilitating understanding of the relative positions of the catheter and sheath. The objective of this study was to demonstrate feasibility, safety, procedural efficiency, and clinical effectiveness of incorporating the new visualizable sheath into a low-fluoroscopy workflow.

Methods
Consecutive de novo paroxysmal AF procedures were performed with a porous tip contact force catheter at a high-volume site between January 2018 and May 2019. Procedures performed with and without the VIZIGO™ EAM-visualizable sheath (Vizigo) were compared. All ablations employed the same standardized low-fluoroscopy workflow. Statistical analyses employed stabilized inverse probability of treatment weights (IPTW) to balance cohorts by operator and key patient characteristics.

Results
Cohorts of 142 Vizigo and 173 non-Vizigo patients were similar at baseline. Use of the Vizigo sheath was associated with approximately 10% improvement in catheter stability (p = 0.0005), 16% reduction in radiofrequency time (p < 0.0001), and 7% fewer ablations that used fluoroscopy (p = 0.0030). There was one cardiac tamponade in each cohort and no deaths, atrioesophageal fistulas, or strokes. Single-procedure freedom from atrial arrhythmia recurrence through 12 months was similar between cohorts (p = 0.9556).

Conclusions
Use of a 3D EAM-visualizable sheath resulted in improved catheter stability, reduced radiofrequency time, and more procedures performed without fluoroscopy, without compromise to safety or effectiveness.