bluuebunny/crossref_metadata_2025_split huggingface dataset:
Involvement of multiple generations in management and internationalization of family firms in Spain: the moderating effect of SEW dimensions
Authors: Blanzo-Mazagatos Virginia , Delgado-García Juan Bautista , Barrero Jesús P. 
Published: September 2022

PurposeThe study aims to analyze for the Spanish context the influence of the involvement of several generations in the firm's management on family firm internationalization. The authors also respond to the call in the literature to consider the influence of SEW on family firm internationalizations by analyzing the moderating effect of the importance family managers attach to each of the socioemotional wealth (SEW) dimensions – enrichment, continuity and prominence on the relationship between multiple generations involved in management and family firm internationalization.Design/methodology/approachThe information was obtained by means of a questionnaire sent to the CEOs of family businesses. The authors’ sample consists of 147 Spanish family firms.FindingsThe authors find that the involvement of multiple generations in management is positively related to the internationalization of family firms. Furthermore, the importance that family CEOs attribute to the enrichment dimension of SEW reduces the intensity of the effect of the involvement of several generations in management on family firm internationalization.Originality/valueThe authors’ results, for the Spanish context, complement previous studies (Meneses et al., 2014) showing that the entry of new generations into the family business opens a window of opportunity for the internationalization of the family business. Furthermore, their study shows that the diverse family objectives by CEOs can have different, even conflicting effects on the internationalization decision. These results suggest that the enrichment dimension, which focuses on the short-term family goals may restrain the internationalization of the family business. However, continuity and prominence dimensions, which are related with long term family objectives and jointly enable the fulfillment of nonfamily stakeholders’ objectives, do not influence the internationalization of the family firms analyzed.
Evaluation of an inpatient sex offender treatment programme for men with intellectual disabilities
Authors: Hickman Gareth , Morris Antonia 
Published: September 2022

PurposeThe purpose of this paper is to report on an inpatient cognitive behavioural sex offender treatment group programme developed and provided to people with intellectual disabilities detained in medium and low security hospital settings. The programme was delivered five times between 2012 and 2020. This paper describes the integration of the programme within a wider treatment pathway model and provides analysis of outcome data.Design/methodology/approachThe programme was evaluated over five group programmes using self-report psychometric measures related to treatment targets in the reduction of sexual offending risk, including cognitive distortions, sexual attitudes and knowledge and locus of control; recidivism data spanning up to 7 years post discharge is also provided. The treatment pathway and a description of the programme are provided.FindingsThe results of this paper showed improvements in sexual knowledge, cognitive distortions and locus of control, however not to a statistically significant degree. No recidivism was observed in the follow-up period.Originality/valueThis paper adds to the evidence base of interventions focused on cognitive behavioural approaches to the treatment and risk reduction of sexual offending in men with intellectual disabilities and adds to the debate regarding the effectiveness of such programmes with offenders with intellectual disabilities.
Next steps toward an inclusive country? Inviting and amplifying youth voice in public anti-hate messaging
Authors: Pollock Mica , Lopez Dolores De los Angeles , Yoshisato Mariko , Kendall Reed , Reece Erika , Kennedy Benjamin Carmichael 
Published: September 2022

Purpose
This paper aims to explore a national anti-hate messaging project, #USvsHate, and its call to students to create public messages refusing “hate, bias, and injustice.” Participants indicated that #USvsHate’s invitation to publicly express students’ ideas about equal human value functioned as a next step in furthering youth voice and critical consciousness toward societal inclusion and justice.

Design/methodology/approach
Using grounded theory, analysis drew from teacher interviews (n = 45), student focus groups (n = 30), anonymous participant questionnaires and student-created messages and backstories (n = 250) gathered between 2017 and 2020.

Findings
Participants indicated #USvsHate’s call to amplify student voice offered a next step to act upon awareness of social issues by denouncing hate while promoting inclusivity. Four invitations related to the project’s “anti-hate message” call emerged as important to participants: the invitation to comment personally on improving society; the creative invitation to share perspectives in any media form; the invitation to speak to a promised public audience; and the invitation to join a collective “us” improving society.

Originality/value
Youth voice and critical consciousness scholarship show the importance of supporting K12 youth to develop abilities to speak about injustice while pursuing an inclusive democracy. Still, less research highlights youth who might enter a classroom with some level of such awareness. This research extends existing scholarship by examining a potential next step to inviting critical consciousness and youth voice in any classroom. It also explores the potential pitfalls of this open-ended approach.
Prevalence of money laundering and terrorism financing through stock market: a comprehensive conceptual review paper
Authors: Akram Tooba , Ramakrishnan Suresh A/I , Naveed Muhammad 
Published: September 2022

Purpose
This paper aims to provide a comprehensive conceptual framework and strong arguments with an intent to examine the stock market variables (predictors) indicating the money laundering (ML) and terrorism financing (FT) proceeds.

Design/methodology/approach
This paper provides a comprehensive review of ML/FT through the stock market across developed, developing and emerging jurisdictions, sheds light on the existing literature and critically evaluates the gap in the relevant studies. Moving forward, this paper develops the conceptual framework and formulates hypotheses to explore the empirical relationship.

Findings
This paper advocates and finds a basis to carry out much-needed empirical research between the ML/FT and stock market keeping in view the growing criminal cases in the developing countries. This paper suggests mining proxies from the publically available stock market data and the results of existing seminal research as variables of the study. These data and results carry information about the ML determinants. After developing hypothetical research providing concepts, this paper also finds that using a suitable methodology, preferable Bayesian logistic and linear regression models, it is possible to find the typologies and factors that can indicate and endorse the use of the stock market for ML/FT. Broadly, it is found that the significance of this study will be two-pronged: empirical development and policy implications.

Research limitations/implications
This paper mainly focuses on the developing region, a newly emerging market and, peculiarly, a grey-listed region by the Financial Action Task Force (FATF).

Practical implications
In light of the existing literature and to the best of the researchers’ knowledge, this study will bring into focus the new age of the action research on the ML regime in the securities markets of the developing countries, hence, the emerging markets. Moreover, this research shall have a sheer significance for the policy measures on FATF recommendations on ML and FT, especially for the countries listed as “grey”.

Social implications
The research based on comprehensive review will help in controlling the social behaviours aiding the proceeds of ML.

Originality/value
This research is extremely novel to the best of the researcher's knowledge.
Exploring the interrelations between additive manufacturing adoption barriers and supply chain vulnerabilities: the case of an original equipment manufacturer
Authors: Naghshineh Bardia , Carvalho Helena 
Published: September 2022

PurposeThis study aims to explore how certain adoption barriers of additive manufacturing (AM) technology may lead to supply chain (SC) vulnerabilities, which in turn would deteriorate supply chain resilience (SCR).Design/methodology/approachA case study of a leading original equipment manufacturer (OEM) that uses AM technology to directly produce end-use metal parts for different industries was performed. Primary data were collected using the in-depth interview method, which was complemented by secondary data from internal and publicly available sources. The findings were compared with the existing literature to triangulate the results.FindingsThe findings indicate that certain AM adoption barriers make the SC vulnerable to reliance on specialty sources, supplier capacity, production capacity, utilization of restricted materials, importance of product purity, raw material availability, unpredictability in customer demand, reliability of equipment, unforeseen technology failures, reliance on information flow, industrial espionage, and utilities availability.Research limitations/implicationsThe SCR outcomes of the identified SC vulnerabilities and their interrelated AM adoption barriers are proposed in this study.Practical implicationsDrawing on the case study findings and the existing literature, several practices are put forward in a framework that supply chain management (SCM) may use to mitigate the identified SC vulnerabilities caused by the AM adoption barriers.Originality/valueThis is the first study to empirically examine and identify the SC vulnerabilities that are caused by the adoption barriers of AM technology.
Family monitoring and the adverse consequences of political connections: does it vary over family generations?
Authors: Hashmi Muhammad Arsalan , Abdullah  , Brahmana Rayenda Khresna 
Published: September 2022

Purpose
This study aims to investigate the impact of family ownership on firm performance. The authors examine whether family ownership in a firm reduces the adverse consequences of political connections on firm performance. Further, the authors analyze whether monitoring benefits of family ownership vary over family generations.

Design/methodology/approach
This study examines the financial data from 229 active nonfinancial firms listed on the Pakistan Stock Exchange between 2011 and 2019. First, the authors estimated several panel data regression models after incorporating control variables in the full sample. Second, the authors estimated models in the subsample of family firms for investigating whether the results vary among different generations of family firms. Further, for checking the robustness of the authors’ statistical results, the authors have used two proxies of family ownership and revalidated the findings in several subsamples of the data.

Findings
This study finds that family firms financially outperform nonfamily firms. Further, the results suggest that boards with family members tend to enhance monitoring and governance mechanisms which reduce the harmful effects of political connections. Finally, this study finds that the monitoring benefits of family ownership which reduce the adverse effects of political connections on family firm performance diminishes over generations.

Originality/value
First, this study provides evidence of whether the monitoring benefits of family ownership reduce the adverse effects of political connections on firm performance. Second, to the best of the authors’ knowledge, no prior study provides evidence whether first-generation family firms are superior in monitoring and ultimately reducing the negative effects of political connections.
Extended epiphenotypes: Integrating epigenotypes into host behavioural manipulation by parasites
Authors: Pavey Chris , Vyas Ajai 
Published: September 2022

Abstract

Biologists have long known that environmental context can create diverse phenotypes from identical genotypes. Thus, cells of the same foetus can grow into various organs depending on the molecular environment. Also, animals of the same genetic heritage can show different behaviours in different environments. Conrad Hal Waddington conceptualized epigenotypes in the 1930s, whereby modifications of genetic material could generate alternative modules of development arising out of nonvariant genetic information. His concept paved the way for a neo‐Darwinian synthesis by creating bidirectionality between the environment and genes.

In a completely independent intellectual universe, Richard Dawkins introduced the idea of extended phenotype in the early 1980s. The hypothesis posits that the appropriate phenotype of genetic information is not limited to the organism but can ‘extend’ beyond the environment. Parasite manipulation of host behaviour presents a dramatic example of such extended phenotypes.

In this perspective, we propose a synthesis between the earlier concept of epigenotypes and the later idea of extended phenotypes, namely a novel concept of extended epiphenotypes.Read the free Plain Language Summary for this article on the Journal blog.
Sepsis associated acute kidney injury in pediatric intensive care unit
Authors: Ozkaya Pinar Yazici , Taner Sevgin , Ersayoğlu Irem , Turan Benay , Yildirim Arslan Sema , Karapinar Bülent , Kaplan Bulut Ipek 
Published: September 2022

AbstractBackgroundWe aimed to compare the acute kidney injury (AKI) incidence in pediatric septic shock patients according to the three different classifications.MethodsWe analyzed retrospectively 52 patients with severe sepsis between January 2019 and December 2019.ResultsWhile 21 patients have been diagnosed with SA‐AKI according to the pRIFLE criteria, 20 children have been diagnosed according to the AKIN criteria, and 21 children have been diagnosed according to the KDIGO criteria. Older age, lower platelet count were determined as independently risk factor for SA‐AKI. Older age and higher PRISM score were associated with mortality. According to Canonical correlation coefficients, pRIFLE is the most successful classification to distinguish AKI state. The canonical correlation coefficients for pRIFLE, KDIGO, and AKIN were 0.817, 0.648, and 0.615, respectively.ConclusionAlthough AKI incidence was similar between the three classifications, pRIFLE was the most successful classification to distinguish AKI state.
Onion (Allium cepa L.) peel: A review on the extraction of bioactive compounds, its antioxidant potential, and its application as a functional food ingredient
Authors: Kumar Manoj , Barbhai Mrunal D , Hasan Muzaffar , Dhumal Sangram , Singh Surinder , Pandiselvam Ravi , Rais Nadeem , Natta Suman , Senapathy Marisennayya , Sinha Neha , Amarowicz Ryszard 
Published: September 2022

AbstractFunctional food development is rapidly increasing as a result of consumer consciousness concerning healthy and nutritious foods. In turn, research exploring novel ingredients for formulating functional foods has been accelerated. Onion peel or skin is a byproduct obtained from onion processing that contains abundant phytochemicals, contributing to its antioxidant potential. The main focus of this review is to highlight different extraction techniques (both conventional and nonconventional) that can be implemented to extract the bioactive compounds from onion peel and assess their antioxidant activity. Furthermore, this review highlights the major areas for the application of onion peel and its extract as prospective functional ingredients, thus aiding in the preparation of designer foods with additional health benefits. The use of onion peel could also assist in redesigning popularly consumed processed foods, such as baked products, noodles or pasta, as packaging material, meat quality improvers, colorants, and juice clarifiers. This review serves as a preliminary document that can assist in exploring different ways of incorporating bioactive onion peels or skin into the functional food industry and concludes that future research can assist in the effective and efficient utilization of this resource.
Single‐layer and double‐layer zein–gum arabic nanoencapsulations: Preparation, structural characterization, thermal properties, and controlled release in the gastrointestinal tract
Authors: Huang Xueying , Ge Xiaohan , Wang Yi 
Published: September 2022

AbstractEncapsulation is one of the most convenient ways to increase the solubility of hydrophobic compounds and enhance the protection of sensitive compounds. The development of natural and edible encapsulation systems is a challenge for the food industry. This study explored two kinds of nanoparticles (NPs) made by zein and gum arabic (GA) and investigated the protective and controlled release effect of the formed NPs on rutin. Single‐layer NPs (ZG) formed with a zein and GA mixture and double‐layer NPs (ZWG) with one inner layer of zein and one outer layer of GA were prepared with a series of mass ratios of zein to GA. The particle size, polydispersity index, and zeta potential were obtained, and the structure and morphology of the NPs were observed using scanning electron microscopy. As shown by the differential scanning calorimeter and thermogravimetric analysis, the heat resistance of ZG is higher than the heat resistance of ZWG. ZG showed slower release of rutin in the simulated gastric and small intestinal solutions than ZWG. These results will help in understanding the different behaviors of protection and controlled release of layered NPs made by mixtures of biopolymers, which can be directly applied to the design of delivery systems of sensitive bioactive compounds in the food industry.
Detection of Epstein–Barr virus in systemic sclerosis patients: A molecular and serological based study
Authors: Machhua Sanghamitra , Sharma Shefali Khanna , Kumar Yashwant , Singh Surjit , Anand Shashi , Handa Sanjeev , Minz Ranjana Walker 
Published: September 2022

AbstractObjectiveThis study aimed to evaluate an association between Epstein–Barr virus (EBV) and systemic sclerosis (SSc).MethodologyOne hundred and fifty (138 female, 12 male) consecutive adult SSc patients fulfilling the American College of Rheumatology (ACR)/ European League Against Rheumatism (EULAR) criteria were included in this cross‐sectional study. Serological analysis by line blot for class immunoglobulin G (IgG) and IgM antibodies against EBV antigen (EBV capsid antigen [VCA] gp125, VCA p19, EBNA‐1, p22, EA‐D) and quantification of EBV DNA in whole blood by real‐time polymerase chain reaction was performed.ResultsClass IgM antibodies against VCA gp125 (22.8% vs 0%, P < .0002), VCA p19 (55.7% vs 4.4%, P < .0001), EBNA1 (35.7% vs 0%, P < .0001), p22 (24.2% vs 0%, P < .0001), EA‐D (14.2% vs 2.2%, P < .04), and class IgG antibodies against p22 (95.7% vs 82.2%, P < .02) and EA‐D (54.2% vs 0%, P < .0001) reactivities were significantly higher in SSc patients than in controls. The past infection was significantly associated with the control group (42.8% vs 91%, P < .0001); and the viral reactivation was significantly associated with the SSc group (55.7% vs 4.4%, P < .0001). Only three (2%) out of 150 SSc patients were positive for EBV DNA, similar to the control group (2%) (P > .9).ConclusionThe study shows a strong serological association of EBV (reactivation stage) with SSc patients in the absence of viral DNA in the circulation, indicating the EBV reservoir or tropism presence elsewhere.
Feasibility and oncological outcomes of video‐assisted thoracic surgery versus thoracotomy for pathologic N2 disease in non–small cell lung cancer: A comprehensive systematic review and meta‐analysis
Authors: Li Xiaogang , Huang Kaili , Deng Hanyu , Zheng Qiangqiang , Xiao Tao , Yu Jinming , Zhou Qinghua 
Published: September 2022

AbstractThis meta‐analysis aimed to evaluate the feasibility and oncological outcomes between video‐assisted thoracic surgery (VATS) and thoracotomy for non–small cell lung cancer (NSCLC) patients with pathologic N2 (pN2) disease. Data for analysis included short‐term outcomes and long‐term outcomes. We calculated the weighted mean differences (WMDs) for continuous data and the results of overall survival (OS) and disease free survival (DFS) were pooled using the hazard ratios (HRs) with 95% confidence intervals (CIs). Heterogeneity was assessed using the Q‐test and I2‐test. Sensitivity analysis was performed to further examine the stability of pooled HRs and WMDs. In the pooled analyses of 10 eligible studies, results showed that VATS for NSCLC patients with pN2 disease yielded significantly less blood loss (WMD = −61.43; 95% confidence intervals [CI], [−87.69, −35.18]; p < 0.001), less post‐operation hospital stay (WMD, −1.62; 95% CI, [−2.96, −0.28]; p = 0.02), and comparable operation time (WMD,  −8.32; 95% CI, [−23.88, 7.23]; p = 0.29), post‐operation complication rate (risk ratio [RR], 0.95; 95% CI, [0.78, 1.15]; p = 0.59), chest tube duration to thoracotomy (WMD, −0.64; 95% CI, [−1.45, 0.17]; p = 0.12), extent of lymph node dissection (WMD, −1.46; 95% CI, [−3.87, 0.95]; p = 0.23) and 1‐year OS (HR, 1.30; 95% CI, [0.96, 1.76]; p = 0.09) than thoracotomy. However, VATS may improve 3‐year OS (HR, 1.26; 95% CI, [1.12, 1.42]; p = 0.0002) and yield comparable 1‐year DFS (HR, 1.14; 95% CI, [0.89, 1.46]; p = 0.32) and 3‐year DFS (HR, 1.03; 95% CI, [0.88, 1.22]; p = 0.70) for NSCLC patients with pN2 disease than thoracotomy. VATS could yield less surgical trauma and improve post‐operative recovery than thoracotomy. Moreover, VATS may improve the oncological outcomes of those patients.
Clinical application of comprehensive genomic profiling panel to thoracic malignancies: A single‐center retrospective study
Authors: Kunimasa Kei , Sugimoto Naotoshi , Kawamura Takahisa , Yamasaki Tomoyuki , Honma Keiichiro , Nagata Shigenori , Kukita Yoji , Fujisawa Fumie , Inoue Tazuko , Yamaguchi Yuko , Kitasaka Mitsuko , Wakamatsu Toru , Yamai Takuo , Yamamoto Sachiko , Hayashi Takuji , Inoue Takako , Tamiya Motohiro , Imamura Fumio , Nishimura Kazuo , Nishino Kazumi 
Published: September 2022

AbstractBackgroundThe usefulness of comprehensive genomic profiling (CGP) panels for thoracic malignancies after completion of the standard treatment is unclear.MethodsThe results of CGP panels for malignant thoracic diseases performed at our hospital between December 2019 and June 2022 were collected. We examined whether CGP panel results led to new treatment, correlated with the effectiveness of immune checkpoint inhibitors (ICIs), or revealed secondary findings related to hereditary tumors.ResultsA total of 60 patients were enrolled, of which 52 (86.6%) had lung cancer. In six (10%) patients, the panel results led to treatment with insurance‐listed molecular‐targeted agents; four patients had EGFR mutations not detected by the real‐time polymerase chain reaction assay and two had MET ex.14 skipping mutations. In small‐cell lung cancer, the tumor mutation burden was high in 4/6 (66.7%) patients and pembrolizumab was available. Another MET ex.14 skipping mutation was detected in two cases with EGFR‐tyrosine kinase inhibitor resistance. ICI efficacy was ≤1 year in patients with STK‐11, KEAP1, and NEF2L2 mutations. A BRCA2 mutation with a high probability of germline mutation was detected in one patient. A thymic carcinoma with no detectable oncogenic mutation responded to second‐line treatment with Tegafur‐Gimeracil‐Oteracil Potassium (TS‐1) for ≥9 years.ConclusionsCGP panels are useful in thoracic malignancies, especially lung cancer, because they can detect overlooked driver mutations and genetic alterations. We believe that the significance of conducting a CGP panel prior to treatment may also exist, as it may lead to the prediction of ICI treatment efficacy.