bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dio come ἀκαλλής. Conseguenze e implicazioni concettuali dell’apofatismo nel Corpus Areopagiticum
Authors: Abbate Michele 
Published: September 2022

Abstract
Within the Neoplatonic tradition, the absolute transcendence of the First Principle—the One-Good, from which the whole reality in its various articulations derives—plays a crucial role. This philosophical perspective implies, particularly in Plotinus and Proclus, some fundamental philosophical consequences, above all the transcendence of the Principle with respect to being and thought as well. This necessarily implies that the One-Good must be conceived of as beyond the intelligible Beauty itself. In this paper I aim to examine the theoretical implications and consequences of this perspective with specific reference to the conception of God’s absolute transcendence outlined within two texts of the Corpus Areopagiticum, overall characterized by the reworking of some fundamental Neoplatonic concepts in the context of Christian theology: the De divinis nominibus and the De mystica theologia. Indeed, in the De divinis nominibus it is shown that the names/predicates attributed to God in the Sacred Scriptures must be understood only in an allegorical-symbolic meaning, because God is above any possible definition. Not even the character of Beauty can be attributed to him, since he radically transcends it: in fact, God constitutes the absolute foundation and the very first source of Beauty itself. Therefore, God must be understood as ἀκαλλής, that is, “devoid of the connotation of Beauty”, precisely because he completely transcends it. In line with this theological and theoretical perspective, in the De mystica theologia a form of radical and absolute apophatism is developed, which in turn must ultimately lead to its own overcoming for the sake of the henosis, the mystical union with God.
Das Verhältnis zwischen Neuplatonismus und Christentum nach Werner Beierwaltes am Beispiel seiner Auslegung des Dionysius Areopagitas
Authors: Scotti Muth Nicoletta 
Published: September 2022

Abstract
The present essay aims first at clarifying Werner Beierwaltes’ understanding of Neoplatonism at large as the accomplishment of Greek philosophy pursued by Plotinus and coherently developed by Proclus. It seeks secondly to locate Beierwaltes’ remarkable effort to trace the “Wirkungsgeschichte” of Neoplatonism. Focus has been placed, thirdly on his understanding of Dionysius Areopagita as the effective mediator of Neoplatonic issues in the Latin philosophical tradition long before the rediscovery of Proclus in the 13. century. Beierwaltes’ understanding of Dionysius’ “Christian Neoplatonism” as a lucky instance of “Hellenization of Christianity” is finally compared with different exegesis provided by Ivánka and Balthasar in the years immediately preceding Beierwaltes’ remarkable Proclus-monography of 1965.
Novel design of honeycomb hybrid sandwich structures under air-blast
Authors: Patel Murlidhar , Patel Shivdayal 
Published: September 2022

In this study, dynamic explicit analysis was performed to examine the air-blast performance of various hybrid sandwich designs in terms of face plate deflections and energy dissipation capacity under the conventional weapons effects program (CONWEP) air-blast loads ranging from 3 kg to 8 kg trinitrotoluene for stand-off distance ranges from 150 mm to 200 mm. The blast resistance of honeycomb sandwich configurations was evaluated using steel honeycomb with different core topologies, crushable Al foam-filled steel honeycomb, and steel or steel with 3D Kevlar/polypropylene laminate employing fiber metal laminate (FML) front face. For an accurate prediction of the deformation mechanism of all steel parts, the Johnson-Cook (J-C) model was used. The composite failure criteria of Hashin, Puck, and Matzenmiller were implemented to accurately examine the fiber and matrix damage behavior. The novel hybrid design of the honeycomb sandwich structure’s blast resistance is improved by the employment of foam-filled honeycomb, an FML front face, and a circular honeycomb core. In comparison to other sandwich configurations, a novel designed hybrid sandwich construction composed of foam filled circular honeycomb with FML front facing and steel back facing (FCH-1KP0.5) achieved the highest blast resistance due to its lowest face deflection with the smallest plastic dissipation energy.
A new model for general practice-led, regional, community-based, memory clinics
Authors: Disler Rebecca , Pascoe Amy , Anderson Holly , Piejko Ewa , Asaid Adel , Disler Peter 
Published: September 2022

Abstract
Background
Dementia is a major international health issue with high impact on the patient, relatives, and broader society. Routine screening for dementia is limited, despite known benefit of early detection and intervention on quality of care and patient outcomes. Screening is particularly limited in rural and regional areas, despite high burden and projected growth of dementia in these populations. The current study aimed to implement a new general practitioner (GP) led, multidisciplinary, model of care providing dementia detection and referral pathway to a community-based specialist clinic across six regional general practices.

Methods
Cross-sectional analysis of dementia screening and referral characteristics in the St Anthony Family Medical Practices group based in the regional area of Loddon-Mallee, Victoria. Data were collected on demographics and relevant medical history. Cognitive state was assessed using the Mini-Mental State Examination (MMSE), GP Assessment of Cognition (GPCog), and Geriatric Depression Scale (GDS). Referrals and referral outcomes were recorded for geriatrician, psycho-geriatrician, or both.

Results
Eight hundred and eighteenth patients over 65 years were screened, accounting for approximately 24.2% of 65 and over presentations for the practice network. Of those screened, 68.9% were indicated for referral and 30.3% of these were successfully referred. Of the indicated patients who received referrals, 34.2% declined. Many who declined referral had intermediate scores on the cognitive assessments utilized.

Conclusion
Standardised models of care, integrated within community services, are necessary to improve access to early detection, referral and quality management of dementia. The St Anthony Memory Service model will be invaluable in informing future service development, and in particular the development of services for people living with dementia in rural and regional communities.
Effect of the combination of bumetanide plus chlorthalidone on hypertension and volume overload in patients with chronic kidney disease stage 4–5 KDIGO without renal replacement therapy: a double-blind randomized HEBE-CKD trial
Authors: Solis-Jimenez Fabio , Perez-Navarro Lucia Monserrat , Cabrera-Barron Ricardo , Chida-Romero Jesus Antonio , Martin-Alemañy Geovana , Dehesa-López Edgar , Madero Magdalena , Valdez-Ortiz Rafael 
Published: September 2022

Abstract
Background
The co-administration of loop diuretics with thiazide diuretics is a therapeutic strategy in patients with hypertension and volume overload. The aim of this study was to assess the efficacy and safety of treatment with bumetanide plus chlorthalidone in patients with chronic kidney disease (CKD) stage 4–5 KDIGO.

Methods
A double-blind randomized study was conducted. Patients were randomized into two groups: bumetanide plus chlorthalidone group (intervention) and the bumetanide plus placebo group (control) to evaluate differences in TBW, ECW and ECW/TBW between baseline and 30 Days of follow-up. Volume overload was defined as ‘bioelectrical impedance analysis as fluid volume above the 90th percentile of a presumed healthy reference population. The study’s registration number was NCT03923933.

Results
Thirty-two patients with a mean age of 57.2 ± 9.34 years and a median estimated glomerular filtration rate (eGFR) of 16.7 ml/min/1.73 m2 (2.2–29) were included. There was decreased volume overload in the liters of total body water (TBW) on Day 7 (intervention: -2.5 vs. control: -0.59, p = 0.003) and Day 30 (intervention: -5.3 vs. control: -0.07, p = 0.016); and in liters of extracellular water (ECW) on Day 7 (intervention: -1.58 vs. control: -0.43, p < 0.001) and Day 30 (intervention: -3.05 vs. control: -0.15, p < 0.000). There was also a decrease in systolic blood pressure on Day 7 (intervention: -18 vs. control: -7.5, p = 0.073) and Day 30 (intervention: -26.1 vs. control: -10, p = 0.028) and in diastolic blood pressure on Day 7 (intervention: -8.5 vs. control: -2.25, p = 0.059) and Day 30 (intervention: -13.5 vs. control: -3.4, p = 0.018).

Conclusion
In CKD stage 4–5 KDIGO without renal replacement therapy, bumetanide in combination with chlorthalidone is more effective in treating volume overload and hypertension than bumetanide with placebo.
Incidence, risk factors, and clinical impact of major bleeding in hospitalized patients with COVID-19: a sub-analysis of the CLOT-COVID Study
Authors: Nakamura Junichi , Tsujino Ichizo , Yachi Sen , Takeyama Makoto , Nishimoto Yuji , Konno Satoshi , Yamamoto Naoto , Nakata Hiroko , Ikeda Satoshi , Umetsu Michihisa , Aikawa Shizu , Hayashi Hiroya , Satokawa Hirono , Okuno Yoshinori , Iwata Eriko , Ogihara Yoshito , Ikeda Nobutaka , Kondo Akane , Iwai Takehisa , Yamada Norikazu , Ogawa Tomohiro , Kobayashi Takao , Mo Makoto , Yamashita Yugo ,   the CLOT-COVID Study Investigators
Published: September 2022

Abstract
Background
The coronavirus disease 2019 (COVID-19) causes extensive coagulopathy and a potential benefit of anticoagulation therapy has been documented for prevention of thromboembolic events. Bleeding events has also been reported as a notable complication; whereas, the incidence, risks, and clinical impact of bleeding remain unclear.

Method
The CLOT-COVID Study was a nationwide, retrospective, multicenter cohort study on consecutive hospitalized patients with COVID-19 in Japan between April 2021 and September 2021. In this sub-analysis, we compared the characteristics of patients with and without major bleeding; moreover, we examined the risk factors for and clinical impact of bleeding events.

Results
Among 2882 patients with COVID-19, 57 (2.0%) had major bleeding. The incidence of major bleeding increased with COVID-19 severity as follows: 0.5%, 2.3%, and 12.3% in patients with mild, moderate, and severe COVID-19, respectively. COVID-19 severity, history of major bleeding, and anticoagulant type/dose were independently and additively associated with the bleeding incidence. Compared with patients without major bleeding, those with major bleeding exhibited a longer duration of hospitalization (9 [6–14] vs 28 [19–43] days, P < 0.001) and higher mortality during hospitalization (4.9% vs. 35.1%, P < 0.001).

Conclusions
In the real-world clinical practice, the incidence of major bleeding was not uncommon, especially in patients with severe COVID-19. Independent risk factors for major bleeding included history of major bleeding, COVID-19 severity, and anticoagulant use, which could be associated with poor clinical outcomes including higher mortality. Precise recognition of the risks for bleeding may be helpful for an optimal use of anticoagulants and for better outcomes in patients with COVID-19.
RETRACTED ARTICLE: Interrelationships between urban policy and climate, with emphasis on the environment
Authors: Dastjerdi Hassan Kamran , Nasrabadi Narjessadat Hossaini 
Published: September 2022

AbstractThere is growing evidence that projected climate change has the potential to significantly affect public health. Many of these effects are likely to be exacerbated by the risks associated with exposure to heat, floods, and chemical and biological pollution in cities. Identifying the effects of climate change on the environment, and the risks and opportunities of adapting to mitigating climate change can help city policies and planning. The stability of urban systems may be jeopardized if appropriate measures are not taken with the urban climate in the field of environment. Studies show that urban life has always been closely related to the natural environment. One of the most important natural factors involved in the typology of cities, which has a very influential role, is climate. In fact, the characteristics and conditions of geographical spaces, especially cities, are due to the natural and abnormal natural possibilities and limitations of natural geographical factors. Because the city originates from the mathematical and relative position, natural factors, especially climate, have a great impact on the typology and natural and human characteristics of cities. In this fundamental article, a descriptive-analytical method has been tried to examine urban space policies with emphasis on the environmental field. The question that arises here is what effect does climate change have on the type and method of policy- making and policy of urban managers in the field environmental? The results show that cities are climatically divided into desert, mountainous and coastal cities that have their own economic and social characteristics. Since environmental issues in any country are largely due to natural conditions and the characteristics of the human environment, knowledge of natural geography and an understanding of the dialectical relationships between the environment and humans are important for analyzing geographical issues. And has a significant role in managing space policy, especially urban space.
Implementation of a software defined FLISR solution on an active distribution grid
Authors: Leniston Darren , Ryan David , Power Clem , Hayes Paul , Davy Steven 
Published: September 2022

Background: The resiliency of the distribution grid is of increasing concern to the distribution system operator (DSO) due to factors such as climate change and the resulting faults caused by inclement weather conditions, leading to service disruption to consumers. Loss of service negatively affects key performance indicators (KPI) of the DSO, such as customer minutes lost (CML) and customer interruptions (CI), leading to financial penalties imposed by the regulator. Methods: In this paper we propose a software-driven Fault Location, Isolation and Service Restoration (FLISR) solution, leveraging modern software and communication technologies married with the DSO's existing infrastructure, to aid fault detection and resolution, with the aim of reducing CMLs & CIs and curtailing the financial penalties incurred. Results: The proposed FLISR solution was trialled in an area of south-east Ireland which sees a higher count of service loss as compared to more inland areas, providing an ideal environment to gauge the effectiveness of the solution. It was found that the solution generated outputs that could potentially lead to the resolution of fault events faster than the current systems in place by the DSO. Conclusions: Based on the results gathered from operating the FLISR solution on an active grid, it has demonstrated that leveraging modern software technologies in tandem with existing grid infrastructure benefits the DSO with reference to grid management and operations and the customer in terms of quality of service site.
The Winnipeg Intraspinal Pressure Monitoring Study (WISP): A protocol for validation of fiberoptic pressure monitoring for acute traumatic spinal cord injury
Authors: Dhaliwal Perry , Wilkinson Marshall , Zeiler Frederick A. 
Published: September 2022

Background
Research efforts have been focused on limiting secondary injury after traumatic spinal cord injury by performing spinal decompression and early optimization of spinal cord perfusion. The Winnipeg Intraspinal Pressure Monitoring Study (WISP) was designed to validate the technique of intraspinal pressure monitoring at the site of injury using a fiberoptic pressure monitor placed at the site of injury.

Objectives
To describe the design of the WISP study.

Study design
Descriptive.

Methods
We explain the current limitations in the available scientific literature around the topic of blood pressure management for acute traumatic spinal cord injury and rational for the WISP study. Then, we describe the design of WISP including the patient selection criteria, study interventions, follow up schedules and outcome measurements. A multitude of future research avenues are also discussed.

Results
The WISP study is a single center pilot study designed to validate the technique of intraspinal pressure monitoring following acute traumatic spinal cord injury. The study involves the measurement of intraspinal pressure from within the subarachnoid space at the site of injury to derive a number of physiological parameters including spinal cord perfusion pressure, spinal cord blood volume, measures of spinal cord compliance and vascular reactivity indices. Twenty eligible patients will be recruited and followed for a period of 12 months with visits scheduled for the first 5 days and 1, 3, 6, and 12 months following surgical intervention.

Conclusions
The WISP study will provide the first attempt in North America at validation of intraspinal pressure monitoring with a fiberoptic pressure monitor at the site of injury. Successful validation will lead to future studies to define optimal spinal cord perfusion pressure, relationships of neural injury biomarkers and outcomes as well as epigenetic studies.

Trial registration
This study has been registered at clinicaltrials.gov (registration# NCT04550117).
The co-occurrence of the SAVA syndemic, depression and anxiety as barriers to antiretroviral therapy adherence among sub-Saharan Africa population groups: A scoping review protocol
Authors: Delport Anton , Tabana Hanani , Knight Lucia , Wouters Edwin 
Published: September 2022

Introduction
The scale-up of access to antiretroviral therapy has transformed HIV from an acute, terminal disease to a manageable chronic illness. Yet, sustaining high levels of antiretroviral therapy adherence remain a challenge, especially in the sub-Saharan Africa region which is disproportionately affected by HIV. This protocol proposes a scoping review to explore literature reporting on the antiretroviral therapy adherence levels among people who experience substance abuse and violence (SAVA) syndemics, as well as mood disorders such as anxiety and depression among people living with HIV in sub-Saharan Africa.

Methods and analysis
This proposed scoping review will follow Arksey and O’Malley’s methodological framework for conducting scoping reviews as refined by Levac et al. The review will follow the Joanna Briggs Institute’s manual for conducting scoping reviews. Literature searches will be conducted using six databases: Academic search complete; APA PsycArticles; CINAHL; MEDLINE; SocINDEX and Web of science. Title screening will see the “Participant, Concept, Context” framework applied to identify relevant literature and will not include the appraisal of search results. Data charting will follow an adapted version of Trico and colleagues’ PRISMA-ScR and results will be mapped descriptively and in tabular format. Furthermore, results will be discussed within the syndemics model of health, and summarised as a biosocial conceptual model.

Ethics and dissemination
The study will make use of secondary data that are readily available to the public and will not require ethical approval. We intend to publish our results in a peer-reviewed journal and disseminate our findings at relevant conferences and seminars.
Pengaruh Faktor Biologis dan Sosial Ekonomi Terhadap Kejadian Gondok di Kismantoro Wonogiri
Authors: Dewi Yulia Lanti Retno , Wiboworini Budiyanti , Widardo Widardo , Augusthina Amelya , Rahayu Dwi 
Published: September 2022

Latar Belakang: Gondok merupakan masalah kesehatan masyarakat di Indonesia. Kecamatan Kismantoro kabupaten Wonogiri merupakan salah satu daerah endemik kekurangan iodium dan telah diketahui lebih dari setengah abad yang lalu. Penelitian ini bertujuan untuk menganalisis pengaruh faktor biologis dan sosial ekonomi terhadap kejadian gondok di Kismantoro, Wonogiri.Metode: Penelitian ini adalah penelitian observasional analitik dengan rancangan kasus kontrol. Data dikumpulkan dengan kuesioner pada orang yang telah diketahui menderita gondok dan tidak sebagai kontrol. Data yang diambil meliputi faktor biologis dan sosial ekonomi. Jumlah subjek penelitian sebanyak 38 orang .Hasil : Penderita gondok sebanyak 55.3%, umur terbanyak diatas 50 tahun 57.9%, jenis kelamin perempuan sebanyak 86.8%, riwayat gondok dalam keluarga 23.7%, pendidikan rendah 73.7%, pekerjaan sebagai petani 60.5% dan pendapatan rendah 63.2%. Uji Fisher menunjukkan perbedaan yang signifikan (p<0.001).Simpulan: Faktor biologis dan faktor sosial ekonomi mempengaruhi kejadian gondok di Kismantoro.Kata kunci: gondok, Kismantoro, Wonogiri, faktor biologis, faktor sosial ekonomiABSTRACTTitle: The Influence of Biological and Socioeconomic Factors on The Event Of Endemic Goiter In Kismantoro, Wonogiri Background: Endemic goiter is a public health problem in Indonesia. Kismantoro sub-district, Wonogiri at Central Java is one of these endemic area. It has been known for a long time, around five decades. This study was aimed at analyzing the influence of biological and socioeconomic factors on the event of endemic goiter.Method: The study is an observational analytic with case control design.A specially designed questionnaires was used to collect the data. Data on biological socioeconomic factors were taken from 38 subjects.Result: Subjects with goiter 55.3 %, 57.9% of subjects with goiter aged >50 y, and 86.8% are females, 23.7% have history of endemic goiter in their families, working as farmer 60.5%, lower education in 73.7%, and lower incomes in 63.2%. Fisher test showed significant result (p<0.001)Conclusion: Biological and socioeconomic factors aggravate endemic goiter in Kismantoro , Wonogiri. Keywords: goiter, Kismantoro, Wonogiri, biological factor, socioeconomic factor