bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aantrekken en afstoten. Over consensualiteit en polarisering in het Nederlandse strafproces
Authors: Crijns J.H. (Jan) , van der Meij P.P.J. (Patrick) 
Published: September 2022

Aantrekken en afstoten. Over consensualiteit en polarisering in het Nederlandse strafproces
We zijn aanbeland in een tijdsgewricht waarin we in de strafrechtspleging zowel tendensen richting verdergaande polarisering als ontwikkelingen richting meer consensualiteit zien. Dit roept de vraag op hoe beide ontwikkelingen kunnen worden verklaard, geduid en gewaardeerd. Ook roept dit de vraag op of dit twee ontwikkelingen zijn met elk hun eigen drijvende krachten die zich toevalligerwijs min of meer gelijktijdig voltrekken, of dat inderdaad sprake is van een onderling verband zoals hiervoor gesuggereerd. En misschien nog wel belangrijker: waar liggen de grenzen als het gaat om polarisering en consensualiteit? Beide ontwikkelingen raken het karakter van het strafproces immers in de kern, nu het strafproces weliswaar op contradictoriteit (of zo men wil: polariteit) is gestoeld maar tevens uitgaat van het ieder vanuit zijn eigen taak en rol, maar toch in gezamenlijkheid bereiken van de centrale doelstellingen van het strafproces, te weten waarheidsvinding en rechtsbescherming. De beschreven ontwikkelingen van polarisering en toenemende consensualiteit staan dan ook niet voor niets al enige tijd in het brandpunt van de belangstelling van de strafrechtspraktijk en de wetenschap. In dit nummer van Boom Strafblad worden zij vanuit verschillende perspectieven in onderling verband besproken en beschouwd, waarbij voornoemde overkoepelende vragen als rode draad dienen.
Niet elke grasduinende mol is een hacker
Authors: Berndsen M. (Michael) , Visser C.J.J. (Christian) 
Published: September 2022

Niet elke grasduinende mol is een hacker. Waarom de Hoge Raad het begrip computervredebreuk te ver heeft opgerekt
In het arrest over de ‘politiemol’ heeft de Hoge Raad onlangs bevestigd dat het opzoeken van informatie in een systeem zonder dat daarvoor een professionele noodzaak bestaat computervredebreuk kan opleveren. Dit geldt ook als men rechtmatig toegang heeft tot dat systeem. In deze bijdrage wordt op grond van de delictsomschrijving en de wetsgeschiedenis betoogd dat de Hoge Raad een onjuiste – want te extensieve – interpretatie van het begrip computervredebreuk heeft gehanteerd.
Potentiële mediationinterventies uit de interpersoonlijke psychotherapie
Authors: Godschalx-Dekker Judith 
Published: September 2022

Potential mediation interventions from interpersonal psychotherapy
Mediation is a process facilitated by legal and psychotherapeutic knowledge and skills. The psychotherapeutic skills of the mediator are interventions from different mediation approaches employed to improve communication between parties. Interpersonal psychotherapy (IPT) is an individual or group treatment to resolve conflict by improving interpersonal contacts through conflict-, communication- and decision analysis and role play. This contribution was written to explain IPT and to explore which interventions are potentially useful for the mediator.
Optimalisasi Pendayagunaan Zakat Melalui Program Beasiswa Prestasi Tahun 2017-2020: Studi Kasus Pada Dompet Dhuafa Waspada Sumatera Utara.
Authors: Suri Atika , Nasution Annio Indah Lestari , Yanti Nursantri 
Published: September 2022

This study was conducted to determine whether the utilization of zakat carried out by Dompet Dhuafa Waspada (DDW) in collaboration with UPZ Bank SUMUT through0the achievement scholarship program has been running optimally or not. This study use a descriptive approach0with the type of research is qualitative, so the data analysis used is0descriptive qualitative analysis. The results of this study indicate that the achievement scholarship program run by DDW in collaboration with UPZ Bank SUMUT has been running optimally. It is evident from the amount of funds obtained since 2017-2020 which has increased, as well as all the efforts they have made to make this program better and more effective. Then this achievement scholarship program has also resulted in significant changes to the lives of the scholarship beneficiaries, starting from the assistance in education costs, increasing skills and knowledge about entrepreneurship. However, there is still a need for further improvements in the implementation of this program so that this program continues to improve and be more optimal.
Keywords: Utilization of zakat, Achievement Scholarship, optimization
The Exquisite Machine
Authors: Harding Sian E. 
Published: September 2022

How science is opening up the mysteries of the heart, revealing the poetry in motion within the machine.
Your heart is a miracle in motion, a marvel of construction unsurpassed by any human-made creation. It beats 100,000 times every day—if you were to live to 100, that would be more than 3 billion beats across your lifespan. Despite decades of effort in labs all over the world, we have not yet been able to replicate the heart's perfect engineering. But, as Sian Harding shows us in The Exquisite Machine, new scientific developments are opening up the mysteries of the heart. And this explosion of new science—ultrafast imaging, gene editing, stem cells, artificial intelligence, and advanced sub-light microscopy—has crucial, real-world consequences for health and well-being.
Harding—a world leader in cardiac research—explores the relation between the emotions and heart function, reporting that the heart not only responds to our emotions, but it also creates them. The condition known as Broken Heart Syndrome, for example, is a real disorder that can follow bereavement or stress. The Exquisite Machine describes the evolutionary forces that have shaped the heart's response to damage, the astonishing rejuvenating power of stem cells, how we can avoid heart disease, and why it can be so hard to repair a damaged heart. It tells the stories of patients who have had the devastating experiences of a heart attack, chaotic heart rhythms, or stress-induced acute heart failure. And it describes how cutting-edge technologies are enabling experiments and clinical trials that will lead us to new solutions to the worldwide scourge of heart disease.
To Study on Knowledge of Onion Crop Production Technology by Farmers Sikar District of Rajasthan, India
Authors: Sharma Kartikeyan , Jahanara . 
Published: September 2022

Agriculture is a major sector of the Indian economy, which provides employment for large proportion of the predominantly rural population. Besides this it also provides food for human consumption and raw materials for industries. There has been tremendous growth (20.32 per cent compound) in exports of processed fruit and vegetables particularly following new economic policies. India is the second largest producer of vegetables in the world next only to China. The average productivity of vegetable crops in India is considerable low (18 metric tons per hectare) as compared to that in other agriculturally developed countries of the world.
Agriculture sectors crop production has its own emphasis and importance. The study was conducted in Sikar district of Rajasthan to measure the knowledge and adoption of onion crop production technology. Total 120 respondents were selected randomly. The data was collected by personal interview method by using pre structure interview schedule later appropriate statistical analysis is done to find out the meaningful results. The majority of the respondents 50 percentage belongs to middle aged group. 35.84 percentage belongs to illiterate and 48.33 percent were doing agriculture as main occupation. 46.67 per cent have medium income level. Majority of 49.17 per cent respondents belongs to low level of knowledge and 44.17 per cent belongs to medium adoption level.
A Comparative Study on Mathematical Problems in Chinese and Japanese Textbooks Using the Synthesized Bloom Taxonomy
Authors: Jin Ziqing , Hong Xingyue , Wen Linzi , Jin Yashi , Jin Xujie , Ye Lixia , Jia Suijun 
Published: September 2022

In order to study the characteristics of the problem design of mathematics textbooks in junior high school, this paper focuses on the comparative study on linear function sections of Chinese textbooks of people’ s edition (P1) and Japanese textbooks named New Mathematics 2 (J1). Using the Synthesized Bloom Taxonomy (SBT), this paper compares the types of mathematical problems in two editions from two dimensions. In the cognitive process dimension, P1 and J1 both put emphasis on gasping basics and the competence to solve simple practical problems. In the knowledge dimension, P1 inclines toward processes of problem solving, requiring a step-by-step approach according to the clues provided and J1 better focus on the diversity and synthesis of the solutions. These results may provide references for mathematics teaching and learning in junior high schools.
Influence of Aspergillus niger Phospho-compost on Growth, Dry Matter Yield and P Uptake of Maize
Authors: Nyamedi Ivy Mamle , Larteh Isaac Tawiah , Kyere Kwabena 
Published: September 2022

Aims: Soils in Ghana's coastal savanna are typically poor in phosphorus (P), which has an impact on crop growth and productivity. The majority of West African phosphate rock formations are not reactive; therefore, their direct applications do not facilitate easy P availability to crops. Co-composting organic waste with phosphate rock and using phosphorus-solubilizing microorganisms is the new paradigm adopted by scientists in response to the lack of P availability (PSMs). The goals of this study were to (1) assess the effect of Aspergillus niger in P dissolution in phosphate rock during composting with citrus waste (CW) and rice straw (RS) and (2) to evaluate the effect of phosphor-compost on growth, dry matter yield and P uptake of maize.
Methodology: Preparation of compost took place at University of Ghana Forest and Horticulture Research Center, Okumaning Camp close to Kade. Citrus waste and rice straw were used as feed stock. Each composting pile contained a mixture of urea, Togo phosphate rock, and feedstock in a 1:3:24 weight-to-weight ratio.
Results: According to the findings, citrus waste feedstock was superior to rice straw in dissolving the P in rock phosphate. In a pot experiment, the phospho-composts were assessed using maize (Zea mays) as the test crop.
Rates of Medicare Enrollment Among Dialysis Patients After Implementation of Medicare Payment Reform and the Affordable Care Act Marketplace
Authors: Wang Virginia , Zepel Lindsay , Hammill Bradley G. , Hoffman Abby , Sloan Caroline E. , Maciejewski Matthew L. 
Published: September 2022

ImportanceMedicare finances health care for most US patients with end-stage kidney disease (ESKD), regardless of age. The 2011 Medicare prospective payment system (PPS) for dialysis reduced reimbursement for hemodialysis, and the 2014 Patient Protection and Affordable Care Act (ACA) Marketplace increased patient access to new private insurance options, potentially influencing organizations that provide health care, such as hospitals, nursing homes, and dialysis facilities, to adjust their payer mix away from Medicare sources.ObjectiveTo describe Medicare enrollment trends among patients with incident ESKD in 2006 to 2016.Design, Setting, and ParticipantsThis retrospective cohort study involved US patients aged 18 to 64 years who were not enrolled in Medicare at dialysis initiation in 2006 to 2016, with 1-year follow-up through 2017. Data analysis was conducted April 2021 to June 2022.ExposuresThe exposure of interest was a 3-category indicator of time, whether patients initiated dialysis before policies were enacted (2006-2010), in the first years of the Medicare ESKD PPS (2011-2013), or during the Medicare ESKD PPS and implementation of the ACA Marketplace (2014-2016).Main Outcomes and MeasuresPatient-level Medicare enrollment through the first year of dialysis. Logistic regression and Cox models were used to examine associations of time, patient characteristics, and Medicare enrollment, adjusting for patient demographic, clinical, and market-level characteristics.ResultsOf 335 157 patients aged 18 to 64 years with ESKD not actively enrolled in Medicare when they initiated dialysis in 2006 to 2016, the mean (SD) age was 49.9 (10.8) years, 198 164 (59.1%) were men, 188 290 (56.2%) were White, and 313 622 (93.6%) received in-center hemodialysis. New Medicare enrollment was higher in 2006 to 2010 (110 582 patients [73.1%]) than after the Medicare ESKD PPS and ACA Marketplace in 2014 to 2016 (55 382 patients [58.5%]). In adjusted analyses, declining Medicare enrollment was associated with implementation of 2011 Medicare ESKD PPS and 2014 ACA policies and was disproportionately lower among younger, racially minoritized, and ethnically Hispanic patients.Conclusions and RelevanceThere was declining Medicare enrollment among new dialysis patients associated with the 2011 Medicare ESKD PPS and 2014 ACA Marketplace that raise concerns about benefits and harms to patients and payers and continued disparities in kidney care. As the dialysis payer mix moves toward higher proportions of patients not covered by Medicare, it will be important to understand the implications for health care system and patient outcomes.
Careful least squares active noise control with no prior secondary path model
Authors: Lopes Paulo A. C. , Gerald José A. B. 
Published: September 2022

SummaryIn feedforward active noise and vibration control (ANVC) or active noise control (ANC), with online secondary path modeling, fast converging overall modeling algorithms may give high modeling errors. These errors are due to the highly correlated inputs, namely the reference and antinoise signals. These high modeling errors can result in poor performance if ignored. However, it is possible to consider these modeling errors in the control filter design, resulting in a careful controller and good performance, as proposed in this work. Careful control is a dual controller feature, which is the solution to the optimal control problem, but this has not been proposed before in the context of ANC. The modeling error covariance matrix (Sigma(n)) is available in the Kalman filter. However, this requires the knowledge of the time‐varying measurement noise power q(n) and state noise. Instead, this work uses a different approach in which the corresponding linear system is solved in a non‐recursive manner. The resulting maximum error is used for a worst‐case estimate of q(n), and, as it turns out, this can be used to get a worst‐case estimate of Sigma(n). A lower control filter update frequency and other optimizations keep computational complexity similar to other approaches. The resulting algorithm has very few easily selected parameters, good performance, does not require any prior secondary path estimate, and adapts to slow and sudden changes in the physical paths without loss of performance or noise overshoots. However, performance can be impaired by large background noise levels.
Effective Sonosensitizer Delivery by Redox Sensitive Nanoparticles for Prostate Cancer Sonodynamic Therapy via Amplifying Oxidative Stress and Peroxidation
Authors: Tong Tongyu , Lei Hanqi , Zhang Shiqiang , Jiang Donggen , Guan Yupeng , Xing Chengyuan , Chen Huikun , Yang Xiangwei , Kang Yang , Pang Jun 
Published: September 2022

AbstractSonodynamic therapy (SDT), a novel noninvasive therapeutic modality, provides many noteworthy benefits by generating reactive oxygen species (ROS). However, water‐insoluble sonosensitizer delivery strategies have continuously underperformed because of unavoidable toxicity and a short circulation time. In this study, l‐cystine derivative‐based biocompatible nanoparticles (NPs) that can be used in SDT and induce limited cytotoxicity are designed and synthesized. After ultrasonic (US) irradiation, these sonosensitizer‐loaded NPs show highly efficient sonodynamic performance that leads to cytotoxic ROS production. The ability to stop and start ROS generation induced by US irradiation enables accurate temporal and spatial control. In vivo and in vitro experiments are systematically performed to investigate the effects of this system on tumors, and the results indicate remarkable tumor suppression via markedly high persistent oxidative stress that induces peroxidation and endoplasmic reticulum stress. Thus, this novel temporally and spatially controllable ROS generation platform offers a safe and effective theranostic strategy for prostate cancer treatment.
Making Highly Elastic and Tough Hydrogels from Doughs
Authors: Nian Guodong , Kim Junsoo , Bao Xianyang , Suo Zhigang 
Published: September 2022

AbstractA hydrogel is often fabricated from preexisting polymer chains by covalently crosslinking them into a polymer network. The crosslinks make the hydrogel swell‐resistant but brittle. This conflict is resolved here by making a hydrogel from a dough. The dough is formed by mixing long polymer chains with a small amount of water and photoinitiator. The dough is then homogenized by kneading and annealing at elevated temperatures, during which the crowded polymer chains densely entangle. The polymer chains are then sparsely crosslinked into a polymer network under an ultraviolet lamp, and submerged in water to swell to equilibrium. The resulting hydrogel is both swell‐resistant and tough. The hydrogel also has near‐perfect elasticity, high strength, high fatigue resistance, and low friction. The method is demonstrated with two widely used polymers, poly(ethylene glycol) and cellulose. These hydrogels have never been made swell‐resistant, elastic, and tough before. The method is generally applicable to synthetic and natural polymers, and is compatible with industrial processing technologies, opening doors to the development of sustainable, high‐performance hydrogels.
Engineering Electro‐Optic BaTiO3 Nanocrystals via Efficient Doping
Authors: Wang Sasa , Zhu Tong , Sabatini Randy , Najarian Amin Morteza , Imran Muhammad , Zhao Ruyan , Xia Pan , Zeng Lewei , Hoogland Sjoerd , Seferos Dwight S. , Sargent Edward H. 
Published: September 2022

AbstractElectro‐optic (EO) modulators provide electrical‐to‐optical signal conversion relevant to optical communications. Barium titanate (BaTiO3) is a promising material system for EO modulation in light of its optical ultrafast nonlinearity, low optical loss, and high refractive index. To enhance further its spontaneous polarization, BaTiO3 can be doped at the Ba and Ti sites; however, doping is often accompanied by ion migration, which diminishes EO performance. Here, donor–acceptor doping and its effect on EO efficiency are investigated, finding that La‐doped BaTiO3 achieves an EO coefficient of 42 pm V−1 at 1 kHz, fully twice that of the pristine specimen; however, it is also observed that, with this single‐element doping, the EO response falls off rapidly with frequency. From impedance spectroscopy, it is found that frequency‐dependent EO is correlated with ion migration. Density functional theory calculations predict that the ion‐migration barrier decreases with La3+ doping but can be recovered with further Mn2+ doping, a finding that prompts to prevent ion migration by incorporating Mn2+ into the Ti‐site to compensate for the charge imbalance.
Tracking Hepatic Ischemia‐Reperfusion Injury in Real Time with a Reversible NIR‐IIb Fluorescent Redox Probe
Authors: Song Dan , Li Chenchen , Zhu Mengting , Chi Siyu , Liu Zhihong 
Published: September 2022

AbstractHepatic ischemia‐reperfusion injury (HIRI) is responsible for liver dysfunction, which involves reactive oxygen species (ROS) as the most critical marker. Real‐time monitoring of ROS during HIRI can provide significant chance for early diagnosis and timely intervention. However, there is no probe available to track ROS fluctuations during HIRI in vivo, as it is extremely challenging to design reversibly responsive fluorescent probe in near‐infrared region. Here, a reversible redox probe REPOMs emitting beyond 1500 nm is proposed to fill the blank, using rare earth ions‐doped nanoparticles as emitter, and molybdenum‐based polyoxometalate nanoclusters as the ROS‐recognition site and emission modulator. REPOMs exhibited excellent response towards the repeated cycle between ROS and glutathione, based on which the time‐resolved ROS changes during HIRI were successfully obtained. This reversible probe may provide a powerful tool to promote the hepatology research in the future.
Titanium‐Catalyzed Exhaustive Reduction of Oxo‐Chemicals
Authors: Han Bo , Ren Chunping , Jiang Min , Wu Lipeng 
Published: September 2022

AbstractCatalytic reduction of carboxylic acids and derivatives all the way to their corresponding methyl‐compounds is very rare and still challenging for homogeneous transition‐metal catalysis. Herein, we report an unprecedented and general catalytic exhaustive reduction of carboxylic functional group straightforwardly to a methyl group. This reaction was achieved using earth‐abundant and readily available titanium as a catalyst. Our system has broad functional group tolerance and works for various other types of oxo‐chemicals such as alcohols, aldehydes, ketones, lactones, and carboxylates (>100 examples). Preliminary mechanistic studies revealed that the in situ‐generated TiIII−H species was vital for this transformation.
DNA replication timing: Biochemical mechanisms and biological significance
Authors: Rhind Nicholas 
Published: September 2022

AbstractThe regulation of DNA replication is a fascinating biological problem both from a mechanistic angle—How is replication timing regulated?—and from an evolutionary one—Why is replication timing regulated? Recent work has provided significant insight into the first question. Detailed biochemical understanding of the mechanism and regulation of replication initiation has made possible robust hypotheses for how replication timing is regulated. Moreover, technical progress, including high‐throughput, single‐molecule mapping of replication initiation and single‐cell assays of replication timing, has allowed for direct testing of these hypotheses in mammalian cells. This work has consolidated the conclusion that differential replication timing is a consequence of the varying probability of replication origin initiation. The second question is more difficult to directly address experimentally. Nonetheless, plausible hypotheses can be made and one—that replication timing contributes to the regulation of chromatin structure—has received new experimental support.
Living prosthetic breast for promoting tissue regeneration and inhibiting tumor recurrence
Authors: Xu Wenting , Huang Yu , Yuen Ho‐Yin , Shi Linli , Qian Haiqing , Cui Lijuan , Tang Mengyu , Wang Jiahui , Zhu Jie , Wang Zhirong , Xiao Long , Zhao Xin , Wang Lihong 
Published: September 2022

AbstractDeveloping a living prosthetic breast to inhibit potential breast cancer recurrence and simultaneously promote breast reconstruction would be a promising strategy for clinical treatment of breast cancer after mastectomy. Here, a living prosthetic breast in the form of injectable gelatin methacryloyl microspheres is prepared, where they encapsulated zeolitic imidazolate framework (ZIF) nanoparticles loaded with small molecules urolithin C (Uro‐C) and adipose‐derived stem cells (ADSCs). Taking advantage of the acidic tumor microenvironment, the ZIF triggered a pH‐sensitive drug release in situ so that Uro‐C can induce tumor cell apoptosis via reactive oxygen species (ROS) generation. Meanwhile, the ADSCs proliferate in situ to promote tissue regeneration. Using such a design, our data showed that the ADSCs maintained viable and proliferate under the inhibitory effect of Uro‐C in vitro. Through ROS generation, Uro‐C also activated a suppressive tumor microenvironment in mice by both re‐polarizing M2 macrophages to M1 macrophages for elevated inflammatory responses, and increasing the ratio between CD8 and CD4 T cells for tumor recurrence inhibition, significantly promoting new adipose tissue formation. Altogether, our results demonstrate that the prepared living prosthetic breast with bifunctional properties can be a promising candidate in clinic involving tumor treatment and tissue engineering in synergy.