bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Penguasaan Konsep Siswa dalam Menyelesaikan Soal Miskonsepsi pada Mata Pelajaran Biologi
Authors: Hajiriah Titi Laily , Harisanti Baiq Muli 
Published: November 2022

This study aims to describe students' mastery of concepts in solving misconceptions in biology subjects. The sample used is grade 12 students majoring in science and using purposive sampling as a sampling technique. The instrument used is in the form of open test questions containing misconceptions that have been validated by 2 experts and are considered valid because they come from a collection of misconceptions with ISBNs. Data analysis used in this study is the CRI technique. The results of the analysis of the research data can be concluded that the level of understanding of students through their CRI analysis is at a level > 2.5 with the category of misconceptions. Based on the results of the study, it can be concluded that grade 12 science students have very low mastery of concepts that trigger misconceptions so that it is necessary to review certain concepts that have been studied.
Induksi Keragaman Genetik pada Tanaman Alocasia Menggunakan Mutagen Kimia Kolkisin
Authors: Damayanti Fitri , A’ini Zakiah Fithah 
Published: November 2022

Alocasia green velvet (neon taro) is one of the ornamental plants that plant lovers hunt. The increasing standard of living and interest in beauty and uniqueness, the demand for this plant has increased. This provides an opportunity for ornamental plant farmers to develop the potential of Alocasia. Genetic diversity in Alocasia is very low because generally these plants are propagated such as vegetative. Therefore, it is necessary to increase genetic diversity so that new types of Alocasia are produced with more attractive leaf shapes, sizes, and coloration. Efforts that can be applied are mutation induction using a chemical mutagen, namely colchicine. The plant material was used that the tuber of the Alocasia plant. The study was conducted using a randomized block design with two factors, the colchicine concentration (0, 10, 15, 20, 25, and 30 mgL-1) and the immersion time (1 and 2 days). The 30 mgL-1 colchicine treatment gave better growth: producing the highest number of leaves, the longest root length, the highest number of shoots and the percentage of sprouting tubers that reached 100%. Colchicine treatment of 10 mgL-1 with immersion time of 1 day resulted in a different leaf shape. Colchicine treatments of 10, 15, 20, and 25 mgL-1 produced plants with younger leaf coloration than the control. As well as the 30 mgL-1 colchicine treatment produced vigorous plants with larger stem sizes.
Influência de protocolo Ovsynch sobre o comportamento sexual e a fertilidade de ovelhas e borregas
Authors: Sousa Francisco Carlos de , Ferreira Kaênia Braga , Ferreira Sabrina Matos 
Published: November 2022

Este estudo teve como objetivo avaliar o comportamento sexual e a fertilidade de ovelhas e borregas após aplicação de um protocolo de indução/sincronização de estro utilizando GnRH. As fêmeas foram distribuídas aleatoriamente em dois grupos experimentais: o grupo 1 (G1) foi constituído de ovelhas pluríparas com 2 a 3 anos de idade, e o grupo 2 (G2) foi composto por borregas, com 7 a 8 meses de idade. Todas as fêmeas foram submetidas ao protocolo Ovsynch, que consistiu na administração de GnRH no dia 0 (D0), d-cloprostenol sete dias mais tarde (D7) e uma segunda dose de GnRH (D9) foi administrada 48 horas após. As observações de estro foram iniciadas imediatamente após a aplicação de PGF2α, sendo realizadas 3 vezes ao dia, com duração de 4 dias. Os animais do G2 não manifestaram sinais de estro. Do total de fêmeas tratadas do G1, 85,7% manifestaram sinais de estro. A taxa de gestação obtida nos animais do G1 foi de 83,3% (5/6), a qual foi confirmada por meio de diagnóstico de gestação positivo aos 40 dias pós-cobertura. Em conclusão, os resultados demonstraram que o tratamento hormonal Ovsynch foi eficiente em induzir/sincronizar o estro, bem como produziu elevada taxa de gestação em ovelhas pluríparas. Entretanto, o mesmo protocolo não se mostrou eficiente em animais jovens (borregas).
Principais evidências clínicas acerca dos tratamentos tópicos atuais para úlcera venosa de perna: uma revisão sistemática
Authors: Nascimento José William Araújo do , Costa Nathália Wanderley , Marcelino Margarida Skarlatty Xavier , Bernardino Polyana Alves , Bernardino Priscila Alves 
Published: November 2022

Objetivo: Analisar as principais evidências clínicas acerca dos tratamentos tópicos atuais para úlcera venosa de perna. Metodologia: Trata-se de uma revisão sistemática realizada por meio do método PRISMA, nas bases de dados eletrônicas PubMed, Scopus e Web of Science, por meio dos seguintes descritores: “venous ulcer” “topical treatment”, “topical management”, “topical wound care” e “dressing”. Foram incluídos textos completos, disponíveis em português, inglês ou espanhol, publicados entre janeiro de 2018 a julho de 2022. Além destes critérios, foram incluídos apenas estudos que abordavam produtos tópicos de tratamento de feridas para gerenciamento de úlceras venosas de perna. Resultados: 12 artigos compuseram a amostra final desse estudo, com maior produção em 2020 (n: 05). Verificou-se uma notável variedade de produtos tópicos para o tratamento de úlceras venosas de perna: aloenxerto de membrana de âmnio/córion humano desidratado, plasma rico em plaquetas autólogo, fatores de crescimento concentrados, tecido adiposo centrifugado, membrana de biopolímero de matriz natural, cobertura de colagenase, papaína 2-4% com bota de Unna, timolol tópico, pomada de iodo cadexômero a 0,9% e ácido hialurônico. Conclusão: Diversos produtos tópicos para o tratamento de úlceras venosas de perna foram identificados na literatura científica, apresentando resultados positivos em relação à cicatrização, redução da área da lesão e melhora da dor nos pacientes acometidos.
Diagnosis of leaf nutrient content for ‘common’ arrowroot plants fertilized with ovine manure
Authors: Lima Raimundo Valdizio Daniel , Borges Francisca Robevania Medeiros , Marinho Albanise Barbosa , Pereira Ednângelo Duarte , Amorim Aiala Vieira 
Published: November 2022

Despite arrowroot’s (Maranta arundinaceae L.) appeal in several industry sectors, which indicates high potential for large-scale production, few studies have investigated the nutritional status of this crop species. Given the economic relevance of the crop and the limited data in the literature, the objective of this work was to evaluate the nutritive effect of the ovine biofertilizer in the cultivation of arrowroot ‘comum’, in two evaluation periods 180 and 272 days after planting (DAP). The experiment was laid out as a split-plot randomized complete block design with four replicates. Leaf contents of nitrogen (N), phosphorus (P), potassium (K), calcium (Ca), magnesium (Mg), sulfur (S), iron (Fe), zinc (Zn), copper (Cu), manganese (Mn), boron (B), and sodium (Na) were determined. High K and Na contents were observed in arrowroot leaves. The sheep biofertilizer is suitable to meet the nutritional needs of arrowroot ‘common’. The continuous application of biofertilizer provided higher levels of nutrients at 272 days after planting.
Autoimagem, estado nutricional e comportamento alimentar de pacientes acompanhados no Centro de Atenção Psicossocial
Authors: Costa Rafaela Lorena Viana , Santos Elis Maria da Costa , Teixeira Lilia Magno de Abreu , Souza Yasmym Dannielle do Espírito Santo , Miranda Leticia Ramos de , Brasil Heloisy Andrea da Costa , Ferreira Rhaissa Pinheiro , Torres Rosileide de Souza , Guterres Aldair da Silva , Barros Edson Raimundo Raiol 
Published: November 2022

Objetivo: Avaliar a autoimagem, estado nutricional e comportamento alimentar usuários do Centro de Atenção Psicossocial. Metodologia: Trata-se de um estudo quantitativo, descritivo e transversal realizado com usuários adultos do CAPS, na região metropolitana de Belém/PA. Foram utilizados questionários com variáveis socioeconômicas e antropométricas, Escala de Silhueta de Kakeshita (1983), Questionário de Evitação de Imagem (BIAQ) e Questionário Holandês de Comportamento Alimentar (QHCA). Para análise estatística foi utilizado o software BioEstat, versão 5.3. Aplicado o teste Shapiro-Wilk, teste de Correlação de Spearman, Teste t de Student e Qui-quadrado. Adotada significância de 5% para o estudo. Resultados: Conforme a faixa etária, tem-se 35+11, 42% mulheres e 58% homens. A maioria era branco (44%), seguido de pardos (34%) e negros (22%). No total, 20 CIDs foram identificados, sendo F10, F31, F32, F29 E F41.2 os prevalentes. 4% estavam com baixo peso, 44% eutróficos, 28% com sobrepeso e 24% com obesidade. Na escala de silhueta, 16 indivíduos apresentaram distorção negativa, 26 positiva e 8 mínima. O sexo masculino apresentou escores maiores de BIAQ e QHCA, 32,5 e 85,2, em oposição a 27,6 e 79,9 do feminino. Encontrada relação significativa e diretamente proporcional entre IMC e QHCA (p<0.001) Conclusão: Embora haja atendimento multidisciplinar nos CAPS, os distúrbios de alimentação e seus impactos na saúde mental são pouco considerados, logo, faz-se necessário estratégias de identificação de risco nutricional referente a autoimagem e seu impacto no Comportamento Alimentar.
Controle da ansiedade no pré e pós operatório de cirurgia bariátrica
Authors: Moura Lucas Figueredo , Trindade Leda Delmondes , Corrêa Renata Queiroz , Teles Gabrielle Souza Silveira , Teles Carolina Pinheiro Machado , Melo Ana Clara Passos 
Published: November 2022

A ansiedade pode estar associada a um risco aumentado de desenvolver obesidade, na medida em que pode provocar alterações da produção do cortisol mediante situações estressoras. Objetivo: identificar os aspectos sociodemográficos, clínicos, IMC e a associação com a presença de comorbidade em portadores de ansiedade submetidos a cirurgia bariátrica. Método: estudo transversal, tipo survey. Utilizou-se um questionário online através da plataforma Google Forms avaliando antes e após a cirurgia. Resultados: amostra composta por 5.160 participantes, dividido em quatro grupos: grupo A, 1.796 indivíduos que não tinham e não desenvolveram ansiedade após a cirurgia; grupo B, 410 indivíduos que tinham ansiedade e permaneceram; grupo C, 1.391 que tinham ansiedade e melhoraram e o grupo D com 1563 participantes que não tinham ansiedade e desenvolveram após a cirurgia. A idade média foi de 37,25 anos, prevalência do sexo feminino, casados, procedentes da região sudeste. Em todos os grupos houve redução significativa do tabagismo, do consumo de bebidas alcoólicas e maior adesão a prática de atividade física após a intervenção cirúrgica. A técnica de Bypass Gástrico foi a mais prevalente. Observou-se que o grupo D desenvolveu ansiedade após a cirurgia e melhora nas comorbidades preexistentes. A síndrome de Dumping foi mais prevalente nos grupos B e D. Conclusão a cirurgia bariátrica favorece a melhora nos níveis de ansiedade e das comorbidades preexistentes, no entanto, é possível que seja um fator de risco para o surgimento de ansiedade naqueles que não a apresentavam antes da intervenção.
Early and midterm results of valve-sparing aortic root reconstruction with a bovine pericardium patch for patients with acute type a aortic dissection
Authors: Yang Jue , Li Xin , Wu Meifen , Wu Jinlin , Chen Zerui , Sun Tucheng , Fan Ruixin , Yu Changjiang 
Published: November 2022

ObjectivesWe evaluated the feasibility, effectiveness, and safety of valve-sparing aortic root reconstruction with a bovine pericardium patch for patients with acute type A aortic dissection (ATAAD).MethodsFrom January 2016 to January 2021, 895 consecutive patients with ATAAD received surgical treatment at our hospital. After applying our exclusion criteria, 508 patients were included in this research. Based on the attending surgeon's judgment and preference, 192 patients underwent our novel surgical novel surgical technique of valve-sparing aortic root reconstruction (repair group [RG]) and 316 patients underwent the Bentall procedure (Bentall group [BG]).ResultsIn the RG, the early mortality rate was 4.2% (8/192). In the BG, the early mortality rate was 5.1% (16/316). There were no significant differences between groups. The incidence of postoperative renal failure in the BG was significantly higher than that in the RG. The mean follow-up time was 2.93 years (standard deviation, ±1.38 years). There were no significant differences between groups regarding ATAAD-related mortality and reoperation. In the RG, the rate of freedom from aortic root reoperation at 5 years was 98.2%, and the grade of aortic regurgitation 6 months later was significant less than that before surgery, and it did not worsen during later follow-up.ConclusionsValve-sparing aortic root reconstruction with a bovine pericardium patch can be successfully performed for selected patients with ATAAD and is associated with low in-hospital and late mortality rates and low root reoperation rates during early and midterm follow-up.
Conduction disorders after transcatheter aortic valve implantation: A comparison between SAPIEN 3 and SAPIEN 3 Ultra balloon-expandable valves
Authors: Monizzi Giovanni , Olivares Paolo , Makmur Giulio , Fabbiocchi Franco , Grancini Luca , Mastrangelo Angelo , Ferrari Cristina , Galli Stefano , Montorsi Piero , Bartorelli Antonio L. 
Published: November 2022

BackgroundConduction disorders (CD) are the most common complications after Transcatheter Aortic Valve Implantation (TAVI). The last generation of Edwards balloon expandable valves, the SAPIEN 3 Ultra (S3U), is provided with an external sealing skirt that aims to further reduce paravalvular leakage (PVL) compared to SAPIEN 3 (S3) and could potentially lead to higher CD rate. We sought to investigate the rate of new-onset CD in patients undergoing TAVI with the S3 or S3U valve.MethodsWe included 582 consecutive patients undergoing TAVI in a single high-volume Center. Patients with previously implanted pacemaker and Valve in valve procedures were excluded. CD rate was evaluated early after implantation and at discharge.ResultsNo significant difference in the overall CD rate was found between S3 and S3U patients both immediately after the procedure (S3 45.5% vs. S3U 41.8%, p = 0.575) and at discharge (S3 30.4% vs. S3U 35.6%, p = 0.348) with low rate of permanent pacemaker implantation (S3 6.3% vs. S3U 5.5%, p = 0.749). No significant differences were found also in patients with pre-existing atrial fibrillation (S3 8.2% vs. S3U 5%, p = 0.648). A significantly lower rate of PVL was found with S3U compared to S3 (S3 42% vs. S3U 26%, p = 0.007). According to the manufacturer’s guidelines we confirmed that S3U were implanted in a significantly higher position compared to S3 (S3 4.89 ± 1.57 mm vs. S3U 4.47 ± 1.36 mm, p = 0.001).ConclusionNo significant difference in the rate of CD, including the need for PPM implantation, was found in patients undergoing TAVI with the S3 compared to S3U. Moreover, S3U significantly reduced the PVL rate.
“I can’t see how people could walk through that exhibit and not be forever changed”: A qualitative analysis exploring the use of art in research dissemination
Authors: Pepe Vincent M. , Sowers Allison , Pimentel Michelle , Hoffman Alexa , Doran Cierrah , Guth Amanda , Khan Sameer , Baronet Willie , Frasso Rosemary 
Published: November 2022

BackgroundArt can be a strong advocacy tool; it can be used to amplify the voices of marginalized communities and can change people’s perceptions of the world and others in it. In 2018, an art exhibit at Jefferson University included the cardboard signs of people who panhandle in Philadelphia as well as excerpts from in-depth interviews with those who panhandle to highlight their lived experiences. While the team published an article about this work, the purpose of this follow-up study is to explore the lasting impact of the exhibit experience on attendees’ perceptions of people who panhandle.MethodsFourteen attendees of the “Signs of Humanity” exhibit were interviewed 18 months later to explore their recollection of their visit and perceptions of the panhandling community. Interviews were recorded, transcribed, and thematic codes were developed in two ways: a priori codes based on literature, and through line-by-line reading of transcripts.ResultsDirected content analysis showed three main areas in which the exhibit resonated with participants: emotional, behavioral, and educational resonance, in addition to a cross-cutting “sticky” theme, referring to the memorable long-term value of the exhibit.ConclusionThis study demonstrates that integrating art into the dissemination phase of research is effective in imbuing long-lasting emotional/behavioral responses in a way that is both accessible and provocative for the lay and scientific communities. This study adds to the body of evidence supporting the efficacy of art as an education tool and supports its use as a way to amplify the voices of marginalized communities.
Clinical characteristics of a male child with non-classic lipoid congenital adrenal hyperplasia and literature review
Authors: Lu Wenli , Zhang Tingting , Zhang Lidan , Wang Xueqing , Lv Sheng , Wang Junqi , Ye Lei , Xiao Yuan , Dong Zhiya , Wang Wei , Sun Shuoyue , Li Chuanyin , Hu Ronggui , Ning Guang , Ma Xiaoyu 
Published: November 2022

BackgroundLipoid congenital adrenal hyperplasia (LCAH) is a rare and severe disorder that is caused by mutations in the steroidogenic acute regulatory protein (StAR). Non-classic LCAH is defined as late-onset glucocorticoid deficiency and even complete male external genitalia in 46,XY individuals. However, to date, few cases of non-classic LCAH have been reported.MethodsIt was attempted to describe the clinical characteristics of a male child with complete male external genitalia in terms of age of onset, adrenal function, and biochemical indicators. Previously reported cases were also reviewed to investigate the relationship of age of onset with enzymatic activity in non-classic LCAH.ResultsThe patient with complete male external genitalia was diagnosed with non-classic LCAH, in which the reason for his referral to a local hospital at the of age 1.25 years was progressive skin hyperpigmentation, and plasma adrenocorticotropic hormone (ACTH) level was elevated to higher than 1,250 pg/ml. The compound heterozygous mutations c.772C&gt;T/c.562C&gt;T in STAR gene were identified via genetic testing. The literature review resulted in identification of 47 patients with non-classic LCAH from 36 families. The mutational analysis showed that c.562C&gt;T mutation was prevalent in patients with non-classic LCAH, accounting for 37.2% of the total mutant alleles, which could reflect the founder effect on the non-classic LCAH population. In total, 28 46,XY patients were reported, including 22 (78.5%) cases with complete male external genitalia and six (21.5%) cases with different degrees of hypospadias.ConclusionThe clinical phenotypes of non-classic LCAH are highly variable. Routine physical examination, laboratory measurement, genetic testing, and, importantly, enzymatic activity assay may facilitate the early diagnosis of non-classic LCAH. The age of primary adrenal insufficiency (PAI) onset may not be a diagnostic basis for non-classic LCAH, and enzymatic activity assay determination may be more effective.
An improved deep extreme learning machine to predict the remaining useful life of lithium-ion battery
Authors: Gao Yuansheng , Li Changlin , Huang Lei 
Published: November 2022

To aim at the problem of inaccurate prediction of the remaining useful life of the lithium-ion battery, an improved grey wolf optimizer optimizes the deep extreme learning machine (CGWO-DELM) data-driven forecasting method is proposed. This method uses the grey wolf optimization algorithm based on an adaptive normal cloud model to optimize the bias of the deep extreme learning machine, the weight of the input layer, the selection of activation function, and the number of hidden layer nodes. In this article, indirect health factors that can characterize the degradation of battery performance are extracted from the discharge process, and the correlation between them and capacity is analyzed using the Pearson coefficient and Kendel coefficient. Then, the CGWO-DELM prediction model is constructed to predict the capacitance of the lithium-ion battery. The remaining useful life of lithium-ion batteries is indirectly predicted with a 1.44 A·h failure threshold. The prediction results are compared with deep extreme learning machines, long-term memory, other prediction methods, and the current public prediction methods. The results show that the CGWO-DELM prediction method can more accurately predict the remaining useful life of lithium-ion batteries.
Levonorgestrel-releasing intrauterine system vs. systemic medication or blank control for women with dysmenorrhea: Systematic review and meta-analysis of randomized controlled trials
Authors: Wang Jing , Deng Ke , Li Ling , Dai Yi , Sun Xin 
Published: November 2022

AimsTo compare efficacy and safety of the levonorgestrel-releasing intrauterine system (LNG-IUS) with systemic medication or blank control in the treatment of dysmenorrhea.MethodsPubMed, EMBASE, the China National Knowledge Infrastructure (CNKI) and Wanfang Data were searched to collect randomized controlled trials (RCTs) comparing LNG-IUS with systemic medication or blank control among women diagnosed with primary dysmenorrhea or secondary dysmenorrhea (adenomyosis or endometriosis) from inception to 2020.04. Der Simonian-Laird random-effect model was used to pool data.ResultsSeventy-one RCTs (6551 patients) were included. Overall bias risk was medium. Sixty-two articles enrolled patients with adenomyosis; LNG-IUS significantly reduced the visual analogue scale (VAS) score compared with the systemic medication group among adenomyosis women at 3 months (standardized mean difference (SMD) = −0.81, 95% confidence interval (CI) −1.22 to −0.40); 6 months (SMD = −1.25, 95%CI: −1.58 to −0.92); 9 months (SMD = −1.23, 95%CI: −1.63 to −0.83); 12 months (SMD = −1.66, 95%CI: −2.14 to −1.18). No difference was found in the incidence of irregular vaginal bleeding (16 RCTs; RR = 0.91, 95%CI: 0.62−1.33, P = 0.63, I2 = 4%) and other adverse outcomes. Sensitivity analysis regarding randomization methods was robust. Nine RCTs enrolled endometriosis women. Pooling results showed no significant difference between LNG-IUS and systemic medication treatment in terms of VAS at 6 months (SMD = −0.27, 95% CI: −0.97–0.43). Moreover, LNG-IUS was associated with higher risk of irregular vaginal bleeding (26.8% vs. 0).ConclusionsLNG-IUS was associated with a reduced severity of dysmenorrhea compared with systemic medication; it was also beneficial for better control of menstrual blood loss and fewer adverse outcomes. Owing to small sample sizes, further well-designed RCTs are warranted to confirm these findings and long-term effects of LNG-IUS in the treatment of dysmenorrhea.
Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42021228343.