bluuebunny/crossref_metadata_2025_split huggingface dataset:
16-ports indoor base station MIMO array for sub-6 GHz 5G applications
Authors: Abouelnaga Tamer Gaber , Zewail Ibrahim , Shokair Mona 
Published: June 2022

AbstractA typical 5G multiple-input and multiple-output (MIMO) system must combine a high number of antennas at both the transmitter and receiver to realize spatial multiplexing capability. In this paper, a wideband 16- element indoor base station (BS) antenna array that can cover 3.3–6.0 GHz is proposed for 5G applications. A π-shaped monopole antenna is designed to cover the Lower band (LTE bands 42/43–N77–N78), the intermediate band (N79), and the higher band (LTE 46). The antenna elements are arranged in a limited space printed on a substrate take the Hexakaidecagon Polygon shape. As the antenna elements are arranged with good isolation, achieving good polarization diversity. The proposed BS array is simulated, fabricated, and tested. The typical results, S-parameters, antenna efficiency, and radiation patterns are investigated. Moreover, to validate the MIMO performances, a very low envelope correlation coefficient (ECC) below 0.02, high antenna efficiency of about 82–93.2% are achieved. The calculated ergodic channel capacity of the 16 × 16 MIMO system reached up to 85 bps/Hz. The proposed antenna array was compared to some other 5G MIMO indoor base station antennas.
SARS-CoV-2 infection in HIV-infected patients: potential role in the high mutational load of the Omicron variant emerging in South Africa
Authors: Tarcsai Katalin Réka , Corolciuc Oliga , Tordai Attila , Ongrádi József 
Published: June 2022

AbstractA new variant of SARS-CoV-2 named Omicron (B.1.1.529) was isolated from an HIV-infected patient in Botswana, South Africa, in November 2021. Whole genome sequencing revealed a multitude of mutations and its relationship to the mutation-rich Alpha variant that had been isolated from a cancer patient. It is conceivable that very high prevalence of HIV-infected individuals as susceptible hosts in South Africa and their immunocompromised state may predispose for accumulation of coronavirus mutations. Coronaviruses uniquely code for an N-terminal 3′ to 5′exonuclease (ExoN, nsp14) that removes mismatched nucleotides paired by the RNA dependent RNA polymerase. Its activity depends preferably on Mg2+ and other divalent cations (manganese, cobalt and zinc). On the contrary, methyl transferase activity of non-structural protein (nsp) 14 and nsp16 both complexed with nsp10 requires Mn2+. Enzymes in successive stages of HIV infections require the same cations. In HIV-infected organisms, a subsequent coronavirus infection encounters with altered homeostasis of the body including relative starvation of divalent cations induced by interleukin production of HIV-infected cells. It is hypothesized that selective diminished efficacy of ExoN in the absence of sufficient amount of magnesium may result in the accumulation of mutations. Unusual mutations and recombinations of heterologous viruses detected in AIDS patients also suggest that long-lasting persistence of superinfecting viruses may also contribute to the selection of genetic variants. Non-nucleoside reverse transcriptase inhibitors partially restore divalent cations’ equilibrium. As a practical approach, implementation of highly active antiretroviral therapy against HIV replication and vaccination against coronaviruses may be a successful strategy to reduce the risk of selection of similar mutants.
Dynamic capabilities in tourism businesses: antecedents and outcomes
Authors: Nguyen Hang T. T. , Pham Hanh Song Thi , Freeman Susan 
Published: June 2022

AbstractThis paper examines dynamic capabilities as a second-order construct and the antecedents and outcomes of dynamic capabilities. Analyzing data collected from 242 tourism firms in Vietnam, this paper finds a positive influence of firms’ human capital, organizational learning, environmental dynamism, and digital marketing on the dynamic capabilities. Dynamic capabilities have a significant and positive impact on these firms’ competitive advantage. The paper contributes to ongoing efforts to measure dynamic capabilities and explore the micro-foundations of dynamic capabilities.
An Update on the Measurement of Motor Cerebellar Dysfunction in Multiple Sclerosis
Authors: Kenyon Katherine Hope , Boonstra Frederique , Noffs Gustavo , Butzkueven Helmut , Vogel Adam P. , Kolbe Scott , van der Walt Anneke 
Published: June 2022

AbstractMultiple sclerosis (MS) is a progressive disease that often affects the cerebellum. It is characterised by demyelination, inflammation, and neurodegeneration within the central nervous system. Damage to the cerebellum in MS is associated with increased disability and decreased quality of life. Symptoms include gait and balance problems, motor speech disorder, upper limb dysfunction, and oculomotor difficulties. Monitoring symptoms is crucial for effective management of MS. A combination of clinical, neuroimaging, and task-based measures is generally used to diagnose and monitor MS. This paper reviews the present and new tools used by clinicians and researchers to assess cerebellar impairment in people with MS (pwMS). It also describes recent advances in digital and home-based monitoring for people with MS.
Metagenomic analysis of the microbiome of the upper reproductive tract: combating ovarian cancer through predictive, preventive, and personalized medicine
Authors: Qin Xu , Zhou Jianglin , Wang Zizhuo , Feng Chenzhao , Fan Junpeng , Huang Jia , Hu Dianxing , Baban Babak , Wang Shengqi , Ma Ding , Sun Chaoyang , Zhou Zhe , Chen Gang 
Published: June 2022

Abstract

Purpose
We investigated whether ovarian cancer could alter the genital microbiota in a specific way with clinical values. Furthermore, we proposed how such changes could be envisioned in a paradigm of predictive, preventive, and personalized medicine (PPPM).

Methods
The samples were collected using cotton swabs from the cervical, uterine cavity, fallopian tubes, and ovaries of patients subjected to the surgical procedures for the malignant/benign lesions. All samples were then analyzed by metagenomic shotgun sequencing. The distribution patterns and characteristics of the microbiota in the reproductive tract of subjects were analyzed and were interpreted in relation to the clinical outcomes of the subjects.

Results
While the ovarian cancer was able to alter the genital microbiota, the bacteria were the dominant microorganisms in all samples across all cohorts in the study (median 99%). The microbiota of the upper female reproductive tract were mainly from the cervical, identified by low bacterial biomass and high bacterial diversity. Ovarian cancer had a distinct microbiota signature. The tubal ligation affects its microbial distribution. There were no different species on the surface of platinum-sensitive ovarian tissues compared to samples from platinum-resistant patients.

Conclusion
The ovarian cancer–induced changes in microbiota magnify the potential of microbiota as a biotherapeutic modality in the treatment of ovarian cancer in this study and very likely for several malignancies and other conditions. Our findings demonstrated, for the first time, that microbiota could be dissected and applied in more specific fashion based on a predictive, preventive, and personalized medicine (PPPM) model in the treatment of ovarian cancer. Utilizing microbiota portfolio in a PPPM system in ovarian cancer would provide a unique opportunity to a clinically intelligent and novel approach in the treatment of ovarian cancer as well as several other conditions and malignancies.
Is a Guru as Good as God? A Vedāntic Perspective
Authors: Gupta Akshay 
Published: June 2022

AbstractWithin Hindu religious contexts, a guru plays a crucial soteriological role, and is sometimes viewed as being as good as God. Questions of a guru’s sphere of epistemic authority thus have far-reaching socioreligious implications. In this paper, I highlight one such implication within the Caitanya Vaiṣṇava tradition. I then analyze various Caitanya Vaiṣṇava texts in order to precisely define the parameters of a guru’s epistemic authority within this tradition. I suggest that the statements made by gurus within this tradition are of a bipartite nature and describe how an understanding of this bipartite nature can lead to social progress within the tradition. In particular, I highlight how the teachings of the Caitanya Vaiṣṇava tradition can be made consistent with contemporary socially progressive values. I also consider some objections and respond to these.
Sub-switching domain effect for analysis the non-linear dielectric behavior of (K0.49 Na0.49Li0.02) (Nb0.98Sb0.02)O3 ceramic based on Rayleigh model
Authors: Atito Ibrahim A. , Shaban H. T. , Salem A. , Ezzeldien Mohammed , Mahmoud Abd El-razek 
Published: June 2022

AbstractThe solid-state sintering technique has been implemented to synthesize (K0.5Na0.5NbO3)-0.02(LiSbO3) (KNN-LS) Pb-free ceramic. The crystal structure, dielectric and ferroelectric properties of the prepared material were investigated. Pure orthorhombic perovskite phase [I(220)/I(002) = 1.68] with Amm2 space group has been detected at room temperature for sintered ceramic. Two anomalous permittivity peaks corresponding to orthorhombic–tetragonal (O–T) phase transition at T = 175 °C and tetragonal–cubic (T–C) phase transition at T = 355 °C have been observed. At polymorphic phase transition, the Rayleigh model shown the extrinsic contributions caused by domain wall motion is about 80%, while the intrinsic contribution attributed to the lattice distortion is about 20%. Ferroelectric properties were investigated in a wide range of temperatures (RT-225)°C. The results shown a conductive material at high temperature due to the higher cation disorder and leakage current above PPT. The present results are interested for understanding the mechanism of t permittivity–temperature behavior of KNN-doped LS ions based on Rayleigh model. The large remnant polarization and low coercive field below PPT make the material a suitable candidate for energy storage application.
Four dimensional spatial sustainability (4DSS): a revolutionary approach toward utopian sustainability
Authors: Najjar Raed 
Published: June 2022

AbstractThis research paper is composed of several interrelated sections that present thought-provoking concepts and debates concerning sustainability. Substantially, it argues the failure of the classical definition of sustainability and underlines serious worldwide challenges that face the planet and mankind due to the questionable current modes of development. Understanding the importance of adopting more comprehensive definition that ensures integrating critical missing aspects; mainly the cultural-historical and temporal analysis, as well as, rethinking the approach when applying that concept is more urgent than ever. In this sense, the author theorizes new ground-breaking definition for sustainability; namely the four dimensional spatial sustainability, and so, develops innovative approaches that effectively facilitate adopting a set of philosophical models pertaining to this revolutionary definition on different temporal scales. The social aspect has far-reaching impacts upon the different models, hence it is considered as chief factor that democratically supports, controls and enhances the other dimensions, i.e. economic, environmental, and cultural-historical. Basically, these models catalyze generating socially-driven synergy that fosters change in key systems, and creates therefore, spatial participative sustainability leading, on the long run, to standardized spatial sustainability featuring what the author calls ‘utopian sustainability’ on global scale.
Proposed EU AI Act—Presidency compromise text: select overview and comment on the changes to the proposed regulation
Authors: Kazim Emre , Güçlütürk Osman , Almeida Denise , Kerrigan Charles , Lomas Elizabeth , Koshiyama Adriano , Hilliard Airlie , Trengove Markus 
Published: June 2022

AbstractWith its proposed EU AI Act, the EU is aspiring to lead the world in admiral AI regulation (April 2021). In this brief, we summarise and comment on the ‘Presidency compromise text’, which is a revised version of the proposed act reflecting the consultation and deliberation by member states and actors (November 2021). The compromise text echoes the sentiment of the original text, much of which remains largely unchanged. However, there are important shifts and some significant changes. Our main comments focus on exemptions to the act with respect to national security; changes that seek to further protect research, development and innovation; and the attempt to clarify the draft legislation’s stance on algorithmic manipulation. Our target readership for this paper is those who are interested in tracking the evolution of the proposed EU AI act, such as policy-makers and those in the legal profession.
Responsibility in Hybrid Societies: concepts and terms
Authors: Meyer Stefanie , Mandl Sarah , Gesmann-Nuissl Dagmar , Strobel Anja 
Published: June 2022

AbstractWith increased digitalization and new technologies, societies are expected to no longer only include human actors, but artificial actors as well. Such a future of societies raises new questions concerning the coexistence, tasks and responsibilities of different actors. Manifold disciplines are involved in the creation of these future societies. This requires a common understanding of responsibility, and of definitions of actors in Hybrid Societies. This review aims at clarifying aforementioned terms from a legal and psychological perspective. Building from this common ground, we identified seven capacities in total which need to be met by actors in societies to be considered fully responsible, in both a legal and moral sense. From a legal perspective, actors need to be autonomous, have capacity to act, legal capacity, and the ability to be held liable. From a psychological perspective, actors need to possess moral agency and can be trusted. Both disciplines agree that explainability is a pivotal capacity to be considered fully responsible. As of now, human beings are the only actors who can, with regard to these capacities, be considered morally and legally responsible. It is unclear whether and to which extent artificial entities will have these capacities, and subsequently, whether they can be responsible in the same sense as human beings are. However, on the basis of the conceptual clarification, further steps can now be taken to develop a concept of responsibility in Hybrid Societies.
Revisiting Darwin's comparisons between human and non-human primate facial signals
Authors: Kavanagh Eithne , Kimock Clare , Whitehouse Jamie , Micheletta Jerome , Waller Bridget M. 
Published: June 2022

Abstract
Darwin and other pioneering scholars made comparisons between human facial signals and those of non-human primates, suggesting that they share evolutionary history. We now have tools available (the Facial Action Coding System) to make these comparisons anatomically based and standardised, as well as analytical methods to facilitate comparative studies. Here we review the evidence establishing a shared anatomical basis between the facial behaviour of human and non-human primate species, concluding which signals are probably related, and which are not. We then review the evidence for shared function and discuss the implications for understanding human communication. Where differences between humans and other species exist, we explore possible explanations and future directions for enquiry.
BROWNLIE IIAND THE SERVICE-OUT JURISDICTION UNDER ENGLISH LAW
Authors: Arzandeh Ardavan 
Published: June 2022

AbstractFS Cairo (Nile Plaza) LLC v Brownlie(Brownlie II) is arguably the United Kingdom's highest appellate court's most significant decision this century on a private international law question. The judgment has ended nearly two decades of debate about the meaning of ‘damage’ sustained in England for the purpose of paragraph 3.1(9)(a) of Practice Direction 6B of the Civil Procedure Rules. In a four-to-one majority ruling, the Supreme Court decided that the provision was to be interpreted widely, such that, in a personal injury claim, any significant harm of any kind suffered by a claimant in England could provide a basis for the service of proceedings on a foreign-based defendant. The article is critical of the majority's decision, as it is liable to create both immediate and long-term problems in the context of the service-out jurisdiction in England. It also examines the court's pronouncements on the other question before it concerning proof of foreign law.
Parents’ talk about conceptual categories with infants: stability, variability, and implications for expressive language development
Authors: WEI Ran , KIRBY Anna , NAIGLES Letitia R. , ROWE Meredith L. 
Published: June 2022

AbstractChildren’s exposure to talk about conceptual categories plays a powerful role in shaping their conceptual development. However, it remains unclear when parents begin to talk about categories with young children and whether such talk relates to children’s language skills. This study examines relations between parents’ talk about conceptual categories and infants’ expressive language development. Forty-seven parent-infant dyads were videotaped playing together at child age 10, 12, 14, and 16 months. Transcripts of interactions were analyzed to identify parents’ talk about conceptual categories. Children’s expressive language development was assessed at 18 months. Findings indicate that parents indeed talked about conceptual categories with infants and that talk was stable across time, with college-educated parents producing more than non-college-educated parents. Further, parents’ talk about conceptual categories between 10 and 16 months predicted children’s 18-month expressive language. This study sheds new light on mechanisms through which early experiences may support children’s language development.
Seismic Sources in Stress‐Induced Anisotropic Media
Authors: Li Wenqiang , Hu Hengshan 
Published: June 2022

AbstractRocks in the upper mantle are extensively subjected to initial stress. The rock exhibits elastic anisotropy under the deviatoric stress, which affects the seismic response of underground structures. This paper aims to study the effect of stress‐induced anisotropy on the seismic source. The seismic moment tensor generated by a shear faulting in a homogeneous isotropic medium with initial stress is derived by using the motion description in the intermediate configuration, the constitutive relation of third‐order elasticity, and the boundary condition considering the effect of initial stress. Then the seismic moment tensor is decomposed to investigate seismic source characters quantitatively. Our results show that shear faulting in a stress‐induced anisotropic medium can produce significant non‐double‐couple (non‐DC) mechanisms, including compensated linear vector dipole (CLVD) and isotropic (ISO) components. ISO and CLVD components vary linearly with the initial shear stress on faults. In addition, stress‐induced anisotropy causes the double‐couple (DC) to deviate from the plane defined by the fault normal and slip direction. The initial stress not only affects the source intensity but also affects the propagation of seismic waves. The radiation patterns of longitudinal waves have non‐uniform lobes, which shows the characteristic of anisotropy. Stress‐induced anisotropic parameters are smaller than intrinsic anisotropy at high‐stress levels and a nearly linear function of the increased initial stress. These results underscore the importance of considering stress‐induced anisotropy in the inversion of focal mechanisms and provide a new perspective for monitoring underground stress.
Ecosystems at Glacier Margins Can Serve as Climate‐Change Laboratories
Authors: Gaglioti B. V. , Mann D. H. , Wiles G. C. 
Published: June 2022

AbstractReconstructing how biota have responded to fast‐paced warming events in the past can help predict their responses to rapid climate changes in the future. Here we suggest that natural communities located near glaciers are useful laboratories for this purpose as they experienced climate changes accentuated by past ice‐margin fluctuations. By reconstructing an Alaskan glacier's position over a 166‐year period and measuring the periglacial air temperatures over the last 3 years, we estimate that the adjacent temperate rainforest episodically cooled and warmed by 0.5–0.7°C/decade. These rates of change exceed most historical warming trends measured elsewhere on Earth and are comparable to the rates of climate warming predicted for the next century. The ring‐width responses of yellow‐cedar trees growing at varying distances from the ice edge illustrate the potential for using periglacial ecosystems to predict how forests may respond to rapid warming in the future.
Periodontitis may induce gut microbiota dysbiosis via salivary microbiota
Authors: Bao Jun , Li Lili , Zhang Yangheng , Wang Min , Chen Faming , Ge Shaohua , Chen Bin , Yan Fuhua 
Published: June 2022

AbstractThe aim of this study was to identify whether periodontitis induces gut microbiota dysbiosis via invasion by salivary microbes. First, faecal and salivary samples were collected from periodontally healthy participants (PH group, n = 16) and patients with severe periodontitis (SP group, n = 21) and analysed by 16S ribosomal RNA sequencing. Significant differences were observed in both the faecal and salivary microbiota between the PH and SP groups. Notably, more saliva-sourced microbes were observed in the faecal samples of the SP group. Then, the remaining salivary microbes were transplanted into C57BL6/J mice (the C-PH group and the C-SP group), and it was found that the composition of the gut microbiota of the C-SP group was significantly different from that of the C-PH group, with Porphyromonadaceae and Fusobacterium being significantly enriched in the C-SP group. In the colon, the C-SP group showed significantly reduced crypt depth and zonula occludens-1 expression. The mRNA expression levels of pro-inflammatory cytokines, chemokines and tight junction proteins were significantly higher in the C-SP group. To further investigate whether salivary bacteria could persist in the intestine, the salivary microbiota was stained with carboxyfluorescein diacetate succinimidyl ester and transplanted into mice. We found that salivary microbes from both the PH group and the SP group could persist in the gut for at least 24 h. Thus, our data demonstrate that periodontitis may induce gut microbiota dysbiosis through the influx of salivary microbes.