bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and influencing factors of pandemic fatigue among Chinese public in Xi'an city during COVID-19 new normal: a cross-sectional study
Authors: Xin Ling , Wang Liuhui , Cao Xuan , Tian Yingnan , Yang Yisi , Wang Kexin , Kang Zheng , Zhao Miaomiao , Feng Chengcheng , Wang Xinyu , Luo Nana , Liu Huan , Wu Qunhong 
Published: September 2022

ObjectiveThis study aimed to assess Chinese public pandemic fatigue and potential influencing factors using an appropriate tool and provide suggestions to relieve this fatigue.MethodsThis study used a stratified sampling method by age and region and conducted a cross-sectional questionnaire survey of citizens in Xi'an, China, from January to February 2022. A total of 1500 participants completed the questionnaire, which collected data on demographics, health status, coronavirus disease 2019 (COVID-19) stressors, pandemic fatigue, COVID-19 fear, COVID-19 anxiety, personal resiliency, social support, community resilience, and knowledge, attitude, and practice toward COVID-19. Ultimately, 1354 valid questionnaires were collected, with a response rate of 90.0%. A binary logistic regression model was used to examine associations between pandemic fatigue and various factors.ResultNearly half of the participants reported pandemic fatigue, the major manifestation of which was “being sick of hearing about COVID-19” (3.353 ± 1.954). The logistic regression model indicated that COVID-19 fear (OR = 2.392, 95% CI = 1.804–3.172), sex (OR = 1.377, 95% CI = 1.077–1.761), the pandemic's impact on employment (OR = 1.161, 95% CI = 1.016–1.327), and COVID-19 anxiety (OR = 1.030, 95% CI = 1.010–1.051) were positively associated with pandemic fatigue. Conversely, COVID-19 knowledge (OR = 0.894, 95% CI = 0.837–0.956), COVID-19 attitude (OR = 0.866, 95% CI = 0.827–0.907), COVID-19 practice (OR = 0.943, 95% CI = 0.914–0.972), community resiliency (OR = 0.978, 95% CI = 0.958–0.999), and health status (OR = 0.982, 95% CI = 0.971–0.992) were negatively associated with pandemic fatigue.ConclusionThe prevalence of pandemic fatigue among the Chinese public was prominent. COVID-19 fear and COVID-19 attitude were the strongest risk factors and protective factors, respectively. These results indicated that the government should carefully utilize multi-channel promotion of anti-pandemic policies and knowledge.
Making high salt concentrations for optimal chromatography compatible with electrospray ionization mass spectrometry using an ion exchange membrane suppressor: Analysis of biomarkers for transporter protein inhibition as a case study
Authors: Wouters Sam , Pijpers Ils , Vanden Haute Ninon , Meston Daniel , Dillen Lieve , Cuyckens Filip , Eeltink Sebastiaan 
Published: September 2022

This study reports on the potential of using ion-exchange suppressor technology in liquid chromatography—electrospray ionization mass spectrometry workflows. The aim was to use high salt concentrations to improve separation performance, while overcoming the resulting significant ion suppression during electrospray ionization. As a case study, we apply suppressor technology to the hydrophilic interaction liquid chromatography separation and detection of taurine and glycochenodeoxycholate sulfate, endogenous biomarkers for organic anion transporter protein inhibition. The desired chromatographic selectivity was achieved applying 100 mM ion-pairing agent, while competing ions negatively affecting MS sensitivity were actively removed post-column from the solvent via a charged partially permeable membrane and replaced with protons, resulting in an up to 10-fold increase in detection sensitivity.
No obvious advantage of hyperthermic intraperitoneal chemotherapy after interval debulking surgery in the treatment of advanced ovarian cancer: A retrospective study
Authors: Lyu Mengmeng , Lu Jin , Shen Yang , Chen Qianqian , Deng Fei , Wang Jinhua 
Published: September 2022

ObjectiveTo study the efficacy of interval debulking surgery (IDS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) compared to IDS alone for the treatment of ovarian cancer after neoadjuvant chemotherapy (NACT).MethodsWe conducted a retrospective study of patients with stage IIIC/IV high-grade serous ovarian carcinoma who underwent surgery at our center from January 2018 to December 2019. Patients who underwent IDS after NACT with (N = 20) or without (N = 42) HIPEC were included. HIPEC was administered after surgery and was combined with 1–2 courses of intraperitoneal hyperthermic perfusion with normal saline only. We analyzed clinical information and outcomes for the two groups.ResultsThe median progression-free survival (PFS) was 14.05 months in the IDS plus HIPEC group and 12.97 months in the IDS group (P = 0.597). The median overall survival (OS) was not reached. After adjustment for age between the two groups, the differences in PFS and OS remained nonsignificant. The change ratio of postoperative CA-125 to preoperative CA-125 was 0.66 in the IDS plus HIPEC group and 0.53 in the IDS group (P = 0.341). The difference in human epididymis protein 4 (HE-4) change ratio between the two groups was nonsignificant (P = 0.225). No significant difference was observed in the occurrence of grade 3 and 4 adverse events between the two groups (P = 0.201).ConclusionAfter NACT, IDS plus HIPEC did not show significant PFS and tumor index change ratio benefits over IDS alone in patients with primary ovarian cancer. Further investigations are needed to assess the role of HIPEC in the treatment of ovarian cancer.
Hospital discharge planning: a qualitative study of new-graduate physiotherapists' experiences
Authors: Martin Romany , Phan Andrew , Tan Shaun , Mandrusiak Allison , Forbes Roma 
Published: September 2022

Purpose: Discharge planning constitutes a large part of a physiotherapist's role when working in hospital settings. The challenges of decision-making relating to discharge planning have been identified by experienced physiotherapists. Despite known challenges associated with the transition from student to clinician, the experiences of new-graduates undertaking discharge planning are largely unknown. Therefore, this study aimed to explore:1) new-graduate physiotherapists' experiences of discharge planning in hospital settings, and2) the influence of pre-professional training on their perceived preparedness for discharge planning.Design: A qualitative general inductive approach using semi-structured interviews. New-graduate physiotherapists (n = 14) working in hospital settings were recruited.Finding: Four themes were generated: 1) responding to the pressures associated with discharging patients, 2) complex decision-making, 3) the role of the interprofessional team, and 4) desiring additional context and complexity from pre-professional training.Practice Implications: The study has identified that new-graduates underestimate the extent to which discharge planning features in their roles within hospital settings, and are unaware of the interprofessional practice required. Whilst they felt that their pre-professional training provides the technical skills required for their roles, they felt that they were not prepared for their role within the broader healthcare system, nor the complexity of clinical practice. This study encourages education providers to emphasise the role of physiotherapists within the broader health care system, through highlighting contexts where physiotherapy knowledge can be applied (i.e., discharge planning) and understanding the role of the physiotherapist within the interprofessional team.Limitations: Important perspectives of mentors and other members of the interprofessional team involved in discharge planning have not been included in this study which may have impacted the interpretation of the results.
The Construction of Ergodic Maps with Prescribed Invariant Density and Power Spectrum Poles
Authors: McDonald Andre , van Wyk Anton 
Published: September 2022

<p>We propose an analytical method for constructing ergodic and piecewise linear hat maps with a piecewise constant invariant density selected to approximate a prescribed invariant density, and a rational power spectral density with an arbitrary number of prescribed nonrepeating poles. These semi-Markov maps permit a matrix representation of the Frobenius-Perron operator, referred to as the Frobenius-Perron matrix. We prove that the poles of a piecewise linear hat map's power spectral density coincide with the unique nonzero and nonunity (in absolute value) eigenvalues of the map's Frobenius-Perron matrix. A hat map is constructed such that it possesses a Frobenius-Perron matrix with a selectable eigenspectrum, thereby allowing for the prescription of its poles. A topological conjugate of this map is subsequently constructed. The conjugate map's poles are equal to those of the original map, but its piecewise constant invariant density is selected to approximate the prescribed invariant density. Similar to previous methods, the novel method does not afford the opportunity to prescribe the zeros of the map's power spectral density. However, unlike these methods, all of the poles are prescribable and no numerical search is performed during construction. We characterize several piecewise linear hat maps constructed using the novel method.</p>
PENGARUH PROMOSI DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN PADA PT. SIMPATIK CABANG UNAAHA KABUPATEN KONAWE
Authors: Melati Melati 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui dan menjelaskan Pengaruh Promosi dan Kualitas Produk Terhadap Keputusan Pembelian Pada PT. Simpatik Cabang Unaaha Kabupaten Konawe. Populasi dalam penelitian ini adalah Populasi dalam penelitian ini adalah sebagian konsumen PT. Simpatik Cabang Unaaha periode Januari s/d Desember 2015 yang berjumlah 482 Orang. Penelitian ini menggunakan analisis regresi linear berganda.

Hasil penelitian menunjukkan bahwa: Secara simultan terdapat pengaruh yang signifikan variabel promosi dan kualitas produk terhadap keputusan pembelian. Fakta ini menunjukkan bahwa semakin baik promosi dan kualitas produk maka semakin tinggi pula keputusan pembelian pada PT.Simpatik Cabang Unaaha.Variabel promosi berpengaruh signifikan terhadap keputusan pembelian. Semakin baik promosi yang diberikan maka semakin tinggi pula keputusan pembelian pada PT.Simpatik Cabang Unaaha. Fakta ini menunjukkan bahwa semakin baik citra merek yang diberikan memiliki kontribusi dalam peningkatan keputusan pembelian.Variabel kualitas produk berpengaruh signifikan terhadap keputusan pembelian. Semakin baik kualitas produk yang diberikan maka semakin tinggi pula keputusan pembelian pada PT.Simpatik Cabang Unaaha. Fakta ini menunjukkan bahwa semakin baik kualitas produk yang diberikan memiliki kontribusi dalam peningkatan keputusan pembelian.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KINERJA PADA TENAGA KERJA BANTUAN (HONORER) DINAS PERHUBUNGAN KOTA BALIKPAPAN
Authors: Cipto Ajeng 
Published: September 2022

In carrying out the functioning of the government of the Balikpapan subdistrict government, the role of outsourced workers is needed to maintain the operational activities in the field. The number of outsourced employees reached 46 people who became total respondents in the implementation of their duties were divided into 10 groups of fields. With the number of operational workers that much, the performance of the transportation service is still considered low. Therefore this study aims to determine the effect of work discipline, compensation, work motivation and competention on the performance of outsourcing employees. Type of research used in this research is quantitative research method. Data collection techniques were conducted through interviews, questionnaires and observations. Testing The reliability of the questionnaire in this study was assisted by SPSS 21 software. The analysis technique used in this study was F-test, t-test and simultaneous discussion. The results of the F-test show that the variables of Work Discipline, Compensation, Work Motivation and Competention of Cooperation together (simultaneously) have an effect on outsourced employee performance, whereas from the T-test results, motivation and Competention variables affect the performance when the work discipline and compensation variables have no effect significantly to performance. Based on the results of simultaneous test or F test F calculate can be concluded that the variable of Work Discipline, Compensation, Work Motivation And Competention simultaneously have a significant influence on employees Performance.
Comparative efficacy of mycophenolic acid and cyclosporine A in treatment of children with steroid-dependent nephrotic syndrome
Authors: Rusakova E. S. , Petrosyan E. K. , Molchanova M. S. , Gavrilova V. A. , Ryzhova A. V. , Kushnir B. L. , Povilaitite P. E. , Shumilov P. V. 
Published: September 2022

BACKGROUND. Steroid-dependent nephrotic syndrome (SDNS) treatment is still an important problem in pediatric nephrology since the proper use of steroid-sparing agents can reduce the frequency of relapses and avoid steroid toxicity. THE AIM of our study was to compare the efficacy of cyclosporine A (CsA) and mycophenolic acid (MPA) in children with SDNS. PATIENTS AND METHODS. We observed 91 children (30 girls, 61 boys) with SDNS in 2015-2020. Age at the disease debut was 3 years [2,1; 5,0]. The age at steroid-sparing therapy debut was 8 years [4,0; 16,0]. All children received standard clinical and laboratory examinations and kidney biopsy. RESULTS: 25 children were treated with CsA, and 66 children were treated with MPA. The steroid-sparing therapy duration was 36 months [29; 44]. The frequency of relapses before the steroid-sparing therapy onset was 1,32 ± 0,62 (0,5; 4,3)/year, during steroid-sparing therapy it became 0,5 ± 0,58 (0; 2)/year (р < 0,05). Relapse rate in the MPA group was 0,36 ± 0,49 (0; 1,76)/year compared to 0,85 ± 0,66 (0; 2)/year in the CsA group (p < 0,05). Withdrawal of prednisolone was achieved in 44 (48,4 %) children. The relapse-free period during steroid-sparing therapy with steroid withdrawal was 25 months [6; 120]. 15 children (16,5 %) showed long–term stable remission with no immunosuppressive therapy. 14 of them were treated with MPA and only one with CsA (χ2=9,7, р = 0,0021). The remission duration was 7-32,9 months. There were no severe side effects of CsA and MPA requiring discontinuation of therapy. CONCLUSION: steroid-sparing therapy of SDNS with CsA and MPA significantly reduces relapse frequency. Relapse risk in patients treated with CsA was significantly higher than with MPA. So, it is justified to prescribe MPA as a first-choice immunosuppressive therapy in patients with SDNS.
Kardiyak Resenkronizasyon Tedavisine Yanıtın Öngörülmesinde Sistemik Bağışıklık-İnflamatuvar İndeksinin Rolü
Authors: ÇELİK Mehmet , KÜP Ayhan , DEMİR Serdar , GÜLŞEN Kamil , İZCİ Servet , YILMAZ Ahmet Seyda , YILMAZ Yusuf , ÇELİK Fatma Betül , KAHRAMAN Fatih , TANIRCAN Muhammed Raşit , ÖZGEYİK Mehmet , USLU Abdulkadi 
Published: September 2022

Objective: Cardiac resynchronization therapy (CRT) is a reliable treatment modality in patients with systolic dysfunction. However, not every patient appears to benefit from CRT. The systemic immune inflammation index (SII) is closely linked to the poor prognosis of various cardiovascular disorders. However, there is no study investigating whether SII has predictive value in determining response to CRT in dilated cardiomyopathy patients. Therefore, we intend to investigate the association between SII and response to CRT.
Methods: A total of 220 patients (mean age 61.2±10.8 years; 120 men) implanted with CRT were involved in this study. Echocardiographic and laboratory measurements were evaluated prior to CRT. Response to CRT was determined as a≥ 15% decrease in left ventricular end-systolic volume at one-year follow-up.
Results: Patients grouped as CRT responders and non-responders. Of these, 143 (64.6%) were considered to be CRT responders, while the remaining 77 (33.4%) were non-responders. Female sex (OR: 3.823, CI: 1.568-9.324 p=0.003), QRS duration (OR: 1.224, CI: 1.158-1.335 p
KARAKTERISASI PEKTIN EKSTRAK BONGGOL PISANG KEPOK (Musa paradisiaca L.)
Authors: Andini Andini , Muhammad Fadli , Istiana Sari Meiria , Joko Raharjo Sentot 
Published: September 2022

Pisang dapat ditemukan di semua di daerah tropis di Indonesia dan memiliki berbagai jenis. Tidak hanya buahnya tapi bonggol pisang juga memiliki kandungan yang bermanfaat yaitu pektin. Pektin merupakan golongan polisakarida pada dinding sel tumbuhan yang mengandung asam galakturonat yang salah satu fungsinya adalah sebagai pengawet. Penelitian ini bertujuan untuk mengekstraksi pektin dari bonggol pisang dan kemudian dilakukan karakterisasi untuk menentukan mutu pektin. Penelitian ini dilakukan dengan metode ekstraksi menggunakan pelarut HCl kemudian ditambahkan etanol ke dalam filtrat untuk mengendapkan pektin dan kemudian dilakukan pengeringan untuk mengendapkan pektin kering. pektin kering kemudian dilakukan karakterisasi dengan beberapa parameter, diantaranya rendemen, bobot pektin, kadar air, kadar abu, berat ekivalen, kadar metoksil, kadar asam galakturonat, dan derajat esterifikasi. Hasil dari pengujian didapatkan data rendemen sebesar 19,6546%; kadar air sebesar 8,19%; kadar abu sebesar 0,3494%; berat ekivalen sebesar 625,211; kadar metoksil sebesar 3,27%; kadar asam galakturonat sebesar 321,94%; dan derajat esterifikasi sebesar 16,89%.
Ethnopharmacology of solanum nigrum: A review
Authors: SD Keerthana , Philip Ashna , Abdul Rehman , M Rupesh Kumar , Syed Sagheer Ahmed , Syed Afrid , DR Bharathi 
Published: September 2022

Solanum nigrum is a flowering plant that originated in Eurasia and has now spread to the Americas, Australia, and South Africa. European black nightshade, blackberry nightshade, or simply black nightshade are all names for this plant. Sn is a vital plant in traditional medicine that may be found all over the world. S. Nigrum, an annual to short-lived perennial herb with white or mauve flowers followed by berries, has been shown to have powerful analgesic, antidiarrheal, antibacterial, antioxidant, and cytotoxic effects. Traditional Indian medicine has employed s.nigrum infusions to treat diarrhoea, gastrointestinal disorders, and fever. The plant's juice is used to treat ulcers and other skin conditions. The fruits are used as a tonic, laxative, and digestive aid.
“O freio da Blazer”, a “cara da dura”: notas sobre itinerários entre a cidade, a arte, institucionalidades e ascendências afro-brasileiras / “The Blazer’s brake”, the “face of the police approach”: notes on itineraries between the city, the art, institutionalities and Afro-Brazilian ancestries
Authors: Campos Marcelo 
Published: September 2022

Este texto trata de observações e notas recentes e inéditas sobre a relação da arte produzida por afrodescendentes e seus mecanismos de institucionalidade. De outro modo, são abordados itinerários que se cruzam com minha própria trajetória na Escola de Belas Artes da Universidade Federal do Rio de Janeiro, frente à rara convivência com pessoas racializadas e a metodologias da história da arte invisibilizadoras da arte dos artistas afro-brasileiros. Apresento, também, relatos, lembranças, histórias trocadas com artistas negras, negros e negres da cidade, cuja convivência se dá em diversos âmbitos, nas salas de aula, ateliês, espaços culturais, resultando em textos, curadorias, acompanhamentos críticos.Palavras-chave: Arte. Afrobrasilidades. Rio de Janeiro. Ativismo. Escola de Belas Artes.AbstractThis text deals with recent and unpublished observations and notes on the relationship between art produced by Afro-descendants and their mechanisms of institutionality. Otherwise, itineraries that intersect with my own trajectory at the School of Fine Arts of the Federal University of Rio de Janeiro are approached, in face of the rare coexistence with racialized people and methodologies from the history of art that make art and Afro-Brazilian artists invisible. I also present reports, memories, stories exchanged with black, and black artists from the city, whose coexistence takes place in different areas, in classrooms, ateliers, cultural spaces, resulting in texts, curatorships, critical accompaniments.Keywords: Art. Afro-Brazilians. Rio de Janeiro. Activism. School of Fine Arts.
Uma vida desfi(l)ada: Maria Bethânia, corpo/signo e significação artística no carnaval carioca / A paraded life: Maria Bethânia, body/sign and artistic significance in the Carioca carnival
Authors: Mangabeira Clark 
Published: September 2022

Com base no desfile campeão da Estação Primeira de Mangueira de 2016, o presente ensaio busca articular a realização do desfile, enquanto representação artística, à sua significação na relação entre tema e estética apresentados na Sapucaí, a partir da presença corporificada da cantora e compositora de fama internacional Maria Bethânia no cortejo, destacando-se qualidades sígnicas que são engendradas na criação do espetáculo para, na Avenida, lugar de resistências afrorreligiosas e populares, se consumar no corpo e por meio dele.Palavras-chave: Carnaval. Escolas de samba. Enredo. Signo. Arte. AbstractFrom the 2016 Estação Primeira de Mangueira’s champion parade, this essay seeks to articulate the realization of the parade itself, as an artistic representation, to its significance in the relationship between theme and aesthetics presented at the Sapucaí, from the embodied presence of the internationally renowned singer and songwriter Maria Bethânia in the procession, to highlight the signed qualities that are engendered in the creation of the show on the Avenida, a place of Afro-religious and popular resistance, and consummate in and through the body.Keywords: Carnival. Samba schools. Carnival plot. Sign. Art.