bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radio AGN in nearby dwarf galaxies: the important role of AGN in dwarf galaxy evolution
Authors: Davis F , Kaviraj S , Hardcastle M J , Martin G , Jackson R A , Kraljic K , Malek K , Peirani S , Smith D J B , Volonteri M , Wang L 
Published: February 2022

ABSTRACT
We combine deep optical and radio data, from the Hyper Suprime-Cam and the Low-Frequency Array (LOFAR), respectively, to study 78 radio active galactic nuclei (AGN) in nearby (z &lt; 0.5) dwarf galaxies. Comparison to a control sample, matched in stellar mass and redshift, indicates that the AGN and controls reside in similar environments, show similar star formation rates (which trace gas availability) and exhibit a comparable incidence of tidal features (which indicate recent interactions). We explore the AGN properties by combining the predicted gas conditions in dwarfs from a cosmological hydrodynamical simulation with a Monte Carlo suite of simulated radio sources, based on a semi-analytical model for radio-galaxy evolution. In the subset of LOFAR-detectable simulated sources, which have a similar distribution of radio luminosities as our observed AGN, the median jet powers, ages, and accretion rates are ∼1035 W, ∼5 Myr, and ∼10−3.4 M⊙ yr−1, respectively. The median mechanical energy output of these sources is ∼100 times larger than the median binding energy expected in dwarf gas reservoirs, making AGN feedback plausible. Since special circumstances (in terms of environment, gas availability, and interactions) are not necessary for the presence of AGN, and the central gas masses are predicted to be an order of magnitude larger than that required to fuel the AGN, AGN triggering in dwarfs is likely to be stochastic and a common phenomenon. Together with the plausibility of energetic feedback, this suggests that AGN could be important drivers of dwarf galaxy evolution, as is the case in massive galaxies.
The dynamics of the TRAPPIST-1 system in the context of its formation
Authors: Huang (黄硕) Shuo , Ormel Chris W 
Published: February 2022

ABSTRACT
TRAPPIST-1 is an 0.09 M⊙ star, which harbours a system of seven Earth-sized planets. Two main features stand out: (i) all planets have similar radii, masses, and compositions; and (ii) all planets are in resonance. Previous works have outlined a pebble-driven formation scenario where planets of similar composition form sequentially at the H2O snowline (∼0.1 au for this low-mass star). It was hypothesized that the subsequent formation and migration led to the current resonant configuration. Here, we investigate whether the sequential planet formation model is indeed capable to produce the present-day resonant configuration, characterized by its two-body and three-body mean motion resonances structure. We carry out N-body simulations, accounting for type-I migration, stellar tidal damping, disc eccentricity-damping, and featuring a migration barrier located at the disc’s inner edge. Due to the sequential migration, planets naturally form a chain of first-order resonances. But to explain the period ratios of the b/c/d-system, which are presently in higher order resonances, we find that planets b and c must have marched across the migration barrier, into the gas-free cavity, before the disc has dispersed. We investigate both an early and late cavity infall scenario and find that the early infall model best matches the constraints, as well as being more probable. After the dispersal of the gaseous disc, stellar tidal torque also contributes towards a modest separation of the inner system. We outline how the insights obtained in this work can be applied to aid the understanding of other compact resonant planet systems.
Orbital architectures of planet-hosting binaries – II. Low mutual inclinations between planetary and stellar orbits
Authors: Dupuy Trent J , Kraus Adam L , Kratter Kaitlin M , Rizzuto Aaron C , Mann Andrew W , Huber Daniel , Ireland Michael J 
Published: February 2022

ABSTRACT
Planet formation is often considered in the context of one circumstellar disc around one star. Yet, stellar binary systems are ubiquitous, and thus a substantial fraction of all potential planets must form and evolve in more complex, dynamical environments. We present the results of a 5 yr astrometric monitoring campaign studying 45 binary star systems that host Kepler planet candidates. The planet-forming environments in these systems would have literally been shaped by the binary orbits that persist to the present day. Crucially, the mutual inclinations of star–planet orbits can only be addressed by a statistical sample. We describe in detail our sample selection and Keck/NIRC2 laser guide star adaptive optics observations collected from 2012 to 2017. We measure orbital arcs, with a typical accuracy of ∼0.1 mas yr−1, that test whether the binary orbits tend to be aligned with the edge-on transiting planet orbits. We rule out randomly distributed binary orbits at 4.7σ, and we show that low mutual inclinations are required to explain the observed orbital arcs. If the stellar orbits have a field binary-like eccentricity distribution, then the best match to our observed orbital arcs is a distribution of mutual inclinations ranging from 0° to 30°. We discuss the implications of such widespread planet–binary alignment in the theoretical context of planet formation and circumstellar disc evolution.
Constraining the shape of Milky Way satellites with distance gradients
Authors: An Zhaozhou , Koposov Sergey E 
Published: February 2022

ABSTRACT
We combine the Dark Energy Camera Legacy Survey DR8 photometry with Gaia photometry to study the 3D structure of Bootes I, Draco, Ursa Minor, Sextans, and Sculptor dwarf galaxies using blue horizontal branch (BHB) stars as distance indicators. We construct a new colour–absolute magnitude of BHB stars that we use to measure the distance gradients within the body of the dwarf galaxies. We detect a statistically significant non-zero gradient only in Sextans and Sculptor. Through modelling of the gradient and 2D density of the systems by triaxial Plummer models, we find that the distance gradients in both dwarf galaxies are inconsistent with prolate shape, but compatible with oblate or triaxial shapes. In order to explain the observed gradients, oblate models of Sextans and Sculptor need to have a significant intrinsic ellipticity larger than 0.47 for Sextans and 0.46 for Sculptor. The flattened oblate shape may imply a significant anisotropy in velocity distribution in order to be consistent with the lack of significant velocity gradients in these systems.
Constraints on r-process nucleosynthesis from 129I and 247Cm in the early Solar system
Authors: Banerjee Projjwal , Wu Meng-Ru , S K Jeena 
Published: February 2022

ABSTRACT
GW170817 has confirmed binary neutron star mergers as one of the sites for rapid neutron capture (r) process. However, there are large theoretical and experimental uncertainties associated with the resulting nucleosynthesis calculations and additional sites may be needed to explain all the existing observations. In this regard, abundances of short-lived radioactive isotopes (SLRIs) in the early Solar system (ESS), which are synthesized exclusively by r-process, can provide independent clues regarding the nature of r-process events. In this work, we study the evolution of r-process SLRIs 129I and 247Cm as well as the corresponding reference isotopes 127I and 235U at the solar location. We consider up to three different sources that have distinct 129I/247Cm production ratios corresponding to the varied r-process conditions in different astrophysical scenarios. In contrast to results reported in a recent study, we find that 129I and 247Cm in the ESS do not come entirely from a single major event but get contributions from at least two more minor contributors. This has a dramatic effect on the evolution of the 129I/247Cm ratio, such that the measured ESS value in meteorites may not correspond to that of the ‘last’ major r-process event. Interestingly, however, we find that the 129I/247Cm ratio, in combination with the observed 129I/127I and 247Cm/235U ratio in the ESS, can still provide important constraints on the properties of proposed r-process sources operating in the Milky Way.
Forensic reconstruction of galaxy colour evolution and population characterization
Authors: Bravo Matías , Robotham Aaron S G , Lagos Claudia del P , Davies Luke J M , Bellstedt Sabine , Thorne Jessica E 
Published: February 2022

ABSTRACT
Mapping the evolution of galaxy colours, from blue star forming to red passive systems, is fundamental to understand the processes involved in galaxy evolution. To this end, we reconstruct the colour evolution of low-redshift galaxies, combining stellar templates with star formation and metallicity histories of galaxies from the Galaxy And Mass Assembly survey and shark semi-analytical model. We use these colour histories to robustly characterize the evolution of red and blue galaxy populations over cosmic time. Using a Gaussian Mixture Model to characterize the colour distribution at any given epoch and stellar mass, we find both observations and simulations strongly favour a model with only two populations (blue and red), with no evidence for a third ‘green’ population. We map the evolution of mean, weight, and scatter of the blue and red populations as a function of both stellar mass and lookback time. Using our simulated galaxy catalogue as a testbed, we find that we can accurately recover galaxies colour histories up to a lookback time of ∼6 Gyr. We find that both populations show little change in the mean colour for low-mass galaxies, while the colours at the massive end become significantly redder with time. The stellar mass above which the galaxy population is predominantly red decreases by 0.3 dex in the last 5 Gyrs. We find a good agreement between observations and simulations, with the largest tension being that massive galaxies from shark are too blue (a known issue with many galaxy evolution models).
Electron scattering emission in the light curves of stars with centrifugal magnetospheres
Authors: Berry I D , Owocki S P , Shultz M E , ud-Doula A 
Published: February 2022

ABSTRACT
Strongly magnetic, rapidly rotating B-type stars with relatively weak winds form centrifugal magnetospheres (CMs), as the stellar wind becomes magnetically confined above the Kepler co-rotation radius. Approximating the magnetic field as a dipole tilted by an angle β with respect to the rotation axis, the CM plasma is concentrated in clouds at and above the Kepler radius along the intersection of the rotational and magnetic equatorial planes. Stellar rotation can bring such clouds in front of the stellar disc, leading to absorption of the order of 0.1 mag ($\sim 10 {{\ \rm per\ cent}}$ of continuum flux). However, some stars with prominent CMs, such as σ Ori E, show an emission bump in addition to absorption dips, which has been so far unexplained. We show that emission can occur from electron scattering towards the observer when CM clouds are projected off the stellar limb. Using the rigidly rotating magnetosphere model, modified with a centrifugal breakout density scaling, we present a model grid of photometric light curves spanning parameter space in observer inclination angle i, magnetic obliquity angle β, critical rotation fraction W, and optical depth at the Kepler radius τK. We show that τK of order unity can produce emission bumps of the magnitude ∼0.05 seen in σ Ori E. We discuss the implications for modelling the light curves of CM stars, as well as future work for applying the radiative transfer model developed here to 3D magnetohydrodynamic simulations of CMs.
The mass profile of NGC 3377 from a Bayesian approach
Authors: Caso Juan P 
Published: February 2022

ABSTRACT
The mass profile for the moderately bright elliptical NGC 3377 is studied through a spherical Jeans analysis, combined with a Bayesian approach. The prior distributions are generated from dark matter simulations and observational constraints. The observational data set consist of Gemini/Gemini Multi-Object Spectrograph long-slit observations aligned with the major and minor axes of the galaxy, and are supplemented with data from the literature for the diffuse stellar component, globular clusters, and planetary nebulae. Although the galaxy is assumed to alternatively reside in central and satellite haloes, the comparison with literature results prefer the latter option. Several options of constant anisotropy are considered, as well as both NFW and Einasto mass profiles. The analysis points to an intermediate mass halo, presenting a virial mass around $(3.6\pm 0.6)\times 10^{11}\, {\rm M_{\odot }}$.
Impact of pain in other body regions on the foot-specific quality of life in patients with hallux valgus
Authors: Mikami Yukio , Yamaguchi Satoshi , Teramoto Atsushi , Amaha Kentaro , Yasui Tetsuro , Kurashige Toshinori , Nagashima Ryota , Endo Jun , Takakura Yoshiyuki , Noguchi Koji , Sadamasu Aya , Kimura Seiji 
Published: February 2022

ABSTRACTObjectivesThe purpose of this study was to clarify the prevalence of pain outside the foot, and to determine the associations of pain outside the foot with foot-specific quality of life (QOL) in patients with hallux valgus.MethodsPatients scheduled to undergo hallux valgus surgery were recruited. Patients answered whether they experienced disabling pain in 13 body regions other than the foot. Foot-specific QOLwas assessed using the Self-Administered Foot Evaluation questionnaire (SAFE-Q). Foot pain was quantified using the visual analogue scale (VAS). Patient characteristics, including age, sex, comorbidity, anxiety, and depression, were also surveyed. The association between pain elsewhere and the SAFE-Q and pain VAS scores were assessed using univariate and multivariate analyses.ResultsOf 102 patients, 55 (54%) experienced pain other than the foot. All SAFE-Q subscale scores were lower, and pain VAS was higher in patients with pain elsewhere than in patients without. In the multivariate analysis, an increase in the number of pain regions was independently associated with a decrease in SAFE-Q scores and an increase in pain VAS.ConclusionMore than half of the patients with hallux valgus experienced pain elsewhere. The presence of pain elsewhere was associated with poorer foot-specific QOL and severer foot pain.
Parental gender bias and investment in children’s health and education: evidence from Bangladesh
Authors: Begum Lutfunnahar , Grossman Philip J , Islam Asad 
Published: February 2022

Abstract
Studies have documented a gender bias in intrahousehold resource allocations in developing countries. Combining a field experiment allocation task and a household survey conducted in Bangladesh, we examine the association between parental gender bias and investment in children’s health and education. The task was designed to circumvent the problem in which children’s education attainment and health status or parents’ expenditure on their children would affect allocation decisions; the outcome did not directly affect the subjects themselves or their own children. The task measures systematic bias arising possibly from sociocultural and religious norms. Biased parents allocate resources in a discriminatory manner. Boy-biased parents are more likely to enrol boys and to spend more on boys’ education. They are less likely to seek formal treatment and to spend less when a girl is sick. Girl-biased parents do not seem to differentiate between sons and daughters with respect to education or health.
Efficacy and Safety of Regdanvimab (CT-P59): A Phase 2/3 Randomized, Double-Blind, Placebo-Controlled Trial in Outpatients With Mild-to-Moderate Coronavirus Disease 2019
Authors: Streinu-Cercel Anca , Săndulescu Oana , Preotescu Liliana-Lucia , Kim Jin Yong , Kim Yeon-Sook , Cheon Shinhye , Jang Young Rock , Lee Sang Joon , Kim Sung Hyun , Chang Ilsung , Suh Jee Hye , Lee Seul Gi , Kim Mi Rim , Chung Da Rae , Kim Han Na , Streinu-Cercel Adrian , Eom Joong Sik 
Published: February 2022

Abstract

Background
Regdanvimab (CT-P59) is a monoclonal antibody with neutralizing activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). We report on part 1 of a 2-part randomized, placebo-controlled, double-blind study for patients with mild-to-moderate coronavirus disease 2019 (COVID-19).

Methods
Outpatients with mild-to-moderate COVID-19 received a single dose of regdanvimab 40 mg/kg (n = 100), regdanvimab 80 mg/kg (n = 103), or placebo (n = 104). The primary end points were time to negative conversion of SARS-CoV-2 from nasopharyngeal swab based on quantitative reverse transcription polymerase chain reaction (RT-qPCR) up to day 28 and time to clinical recovery up to day 14. Secondary end points included the proportion of patients requiring hospitalization, oxygen therapy, or mortality due to COVID-19.

Results
Median (95% CI) time to negative conversion of RT-qPCR was 12.8 (9.0–12.9) days with regdanvimab 40 mg/kg, 11.9 (8.9–12.9) days with regdanvimab 80 mg/kg, and 12.9 (12.7–13.9) days with placebo. Median (95% CI) time to clinical recovery was 5.3 (4.0–6.8) days with regdanvimab 40 mg/kg, 6.2 (5.5–7.9) days with regdanvimab 80 mg/kg, and 8.8 (6.8–11.6) days with placebo. The proportion (95% CI) of patients requiring hospitalization or oxygen therapy was lower with regdanvimab 40 mg/kg (4.0% [1.6%–9.8%]) and regdanvimab 80 mg/kg (4.9% [2.1%–10.9%]) vs placebo (8.7% [4.6%–15.6%]). No serious treatment-emergent adverse events or deaths occurred.

Conclusions
Regdanvimab showed a trend toward a minor decrease in time to negative conversion of RT-qPCR results compared with placebo and reduced the need for hospitalization and oxygen therapy in patients with mild-to-moderate COVID-19.

Clinical trial registration.
NCT04602000 and EudraCT 2020-003369-20.
Do patient-reported measures of disease activity in rheumatoid arthritis vary between countries? Results from a Nordic collaboration
Authors: Delcoigne Bénédicte , Provan Sella Aarrestad , Hammer Hilde Berner , Di Giuseppe Daniela , Frisell Thomas , Glintborg Bente , Grondal Gerdur , Gudbjornsson Bjorn , Hetland Merete Lund , Michelsen Brigitte , Nordström Dan , Relas Heikki , Askling Johan 
Published: February 2022

Abstract

Objectives
To investigate whether patient-reported outcomes vary across countries and are influenced by cultural/contextual factors. Specifically, we aimed to assess inter-country differences in tender joint count (TJC), pain and patient’s global health assessment (PGA), and their impact on disease activity (DAS28-CRP) in RA patients from five Nordic countries.

Methods
We collected data (baseline, 3- and 12-months) from rheumatology registers in the five countries comprising RA patients starting a first ever MTX or a first ever TNF inhibitor (TNFi). In order to assess the role of context (=country), we separately modelled TJC, pain and PGA as functions of objective variables (CRP, swollen joint count, age, sex, calendar period and disease duration) with linear models. Analyses were performed at each time point and for both treatments. We further assessed the impact of inter-country differences on DAS28-CRP.

Results
A total of 27 645 RA patients started MTX and 19 733 started a TNFi. Crude inter-country differences at MTX start amounted to up to 4 points (28 points scale) for TJC, 10 and 27 points (0–100 scale) for pain and PGA, respectively. Corresponding numbers at TNFi start were 3 (TJC), 27 (pain) and 24 (PGA) points. All differences were reduced at 3- and 12-months, and attenuated when adjusting for the objective variables. The variation in predicted DAS28-CRP across countries amounted to &lt;0.5 units.

Conclusions
Inter-country differences in TJC, pain and PGA are greater than expected based on differences in objective measures, but have a small clinical impact on DAS28-CRP across countries.
Trait coordination at leaf level explains the resistance to excess light stress in shade-tolerant tropical tree species
Authors: Cifuentes Lucas , Moreno Flavio 
Published: February 2022

AbstractPlant functioning in response to the environment is an important issue for vegetation reassembly of degraded lands because of both low and excessive sunlight influence the performance of young plants. However, how shade-tolerant tree species deal with excess of light energy remains unclear due to the contrasting results among studies and the subjective classifications of species shade tolerance. From a quantitative classification of shade tolerance of 12 tropical tree species planted in the field under contrasting light conditions, we hypothesized that shade-tolerant species are capable of effective long-term acclimation to high-light conditions. Plant size and survival of species were measured at the beginning and 38 months after planting. We also measured functional traits associated with carbon economy and non-photochemical energy dissipation. Under high-light condition, more light-demanding species showed higher growth rates associated with higher values of functional traits that improve the CO2 assimilation capacity. By contrast, more shade-tolerant species showed higher survival that was associated with higher values of qN, leaf K contents and leaf thickness. The concomitant increase in these traits, as well as their greater plasticity to light in WUEi, Fv/Fm and qN, confers on these species strong photoprotection to avoid high-light stress and to persist under open field conditions. The results challenge the common assumption that only fast-growing and light-demanding tree species are suitable for vegetation reassembly in full sunlight conditions and to improve the environmental conditions for other species.
An Outcomes-Oriented Approach to Residency Selection: Implementing Novel Processes to Align Residency Programs and Applicants
Authors: Caretta-Weyer Holly A. 
Published: February 2022

Residency application numbers have skyrocketed in the last decade, and stakeholders have scrambled to identify and deploy methods of reducing the number of applications submitted to each program. These interventions have traditionally focused on the logistics of the application submission and review process, neglecting many of the drivers of overapplication. Implementing application caps, preference signaling as described by Pletcher and colleagues in this issue, or an early Match does not address the fear of not matching that applicants hold, the lack of transparent data available for applicants to assess their alignment with a specific program, or issues of inequity in the residency selection process. Now is the time to reconsider the residency selection process itself.
As competency-based medical education emerges as the predominant educational paradigm, residency selection practices must also shift to align with societal, specialty, and program outcomes. The field of industrial and organizational psychology offers a multitude of tools (e.g., job analysis) by which to define the necessary outcomes of residency training. These tools also provide programs with the infrastructure around which to scaffold an outcomes-oriented approach to the residency selection process. Programs then can connect residency selection to training outcomes, longitudinal assessment modalities, and the evolving learning environment.
To achieve an outcomes-oriented residency selection process, stakeholders at all levels will need to invest in coproducing novel ways forward. These solutions range from defining program priorities to implementing national policy. Focusing on outcomes will facilitate a more transparent residency selection process while also allowing logistics-level interventions to be successful, as applicants will be empowered to better assess their alignment with each program and apply accordingly.