bluuebunny/crossref_metadata_2025_split huggingface dataset:
An OPD base Agni Karma (An Ayurvedic therapeutic burn) intervention in Plantar Corn: A case study
Authors: Dhaliya Ravi , Gupta Arjun , Chauhan Kanchan 
Published: January 2022

A Corn is a specially-shaped callus of dead skin that occurs on the thin or glabrous surface of the toe. It presses upon the adjacent tissues and causes severe pain when pressed due to pressure on the nerves. Plantar corns are recalcitrant to the medical line of treatment and being very painful need surgical intervention. Surgery is rarely indicated since the rate of recurrences is as high as with conservative therapy The management of Kadara is aimed at the removal of the hyperkeratosis lesion by Snigdha Agni Karma along with Shastra Karma. Here, we demonstrated an OPD base simple and effective ancient technique in corns as described in Samhita which found to be very beneficial.
Developing a Fuzzy Time Series Forecasting Model Based on Hedge Algebras and Particle Swarm Optimization
Authors: Tinh Nghiem Van , Duy Nguyen Tien , Thanh Tran Thi 
Published: January 2022

In recent years, numerous fuzzy time series (FTS) forecasting models have been widely used. One of the important factors for obtaining high forecasting accuracy in fuzzy time series model is that the lengths of intervals in the universe of discourse. In this study, a hybrid forecasting model which uses hedge algebra (HA) and particle swarm optimization (PSO) is proposed to determine optimal lengths of intervals in FTS models. In that, HA is utilized as a tool to partition the universe of discourse into intervals with unequal-size corresponding to the semantic intervals calculated from the linguistic terms. After processing of generating the intervals, we define fuzzy sets based on the observation data of times series and use them to establish fuzzy relationship groups. Then, the proposed model is combined with the PSO technique to find the appropriate length of each interval with view to reaching the better forecasting accuracy rate. The performance of the proposed model is evaluated with the historical data of enrolments at the University of Alabama. The simulated results obtained indicate that the proposed model achieves higher forecasting accuracy compared other existing forecasting models and it can obtain better quality solutions for both the 1st-order and high-order FTS model.
HIGHLIGHTS

In fuzzy time series forecasting model, the length of intervals and the order of fuzzy relationships are two critical factors for forecasting accuracy
Hedge algebra and PSO are utilized as a tool to partition the universe of discourse into intervals with unequal - size corresponding to the semantic intervals calculated from the linguistic terms
The defuzzification principles are used to calculate the forecasting results based on the fuzzy relationship groups

GRAPHICAL ABSTRACT
DEVELOPMENT OF CITIZENSHIP LEARNING BASED ON MORAL INTELLIGENCE AS A SYSTEM PROGRAM FOR CULTURING MAIN CHARACTER VALUES
Authors: Setiawan Deny , Wahyudi Arief 
Published: January 2022

This research was motivated by the factual condition of the occurrence of a moral crisis among Indonesia's young generation, including the weak culture of the main character values. This development research was aimed to develop moral intelligence-based Citizenship Education learning as a systemic program for the culture of the main character values. The scope of this research was limited to the study of civics learning based on moral intelligence as a systemic program of cultivating character values among students. The research method was used by the Research & Development. The research subjects involved: (1) a lecturer who taught introduction courses of civics; (2) students is limited group trials as subject; and (3) three experts for the validation of teaching materials who had criteria for Citizenship Education experts including: politics, law, and moral philosophy. The instrument was used an expert validation questionnaire which was analyzed using the Percentage Mean Score (PRS). The results of the research showed that civics learning textbook based on intelligent moral that developed was very valid and suitable for being used and giving contribution on the strengthen of character for students in their scope life in global era that full of change and value paradoxes.
Analisis kualitas layanan pada CU Lantang Tipo di Balai Sepuak
Authors: Krisnawati Ira , Wahyudi Hijrah , Sari Angelina Fitria Rina 
Published: January 2022

Tujuan – Penelitian ini bertujuan untuk mengetahui Analisis Kualitas Layanan Pada CU Lantang Tipo di Balai Sepuak, yang terdiri dari aspek bukti fisik, empati, daya tanggap, keandalan dan jaminan..
Desain/Methodologi/Pendekatan – Penelitian ini merupakan penelitian deskriptif, metode yang digunakan dalam penelitian ini adalah metode kuantitatif, dengan pernyataan persepsi. Nilai persepsi responden menyatakan cukup Puas. Subjek yang digunakan adalah Anggota di CU Lantang Tipo di Balai Sepuak yang berjumlah 30 orang. Teknik analisis data menggunakan skala Ordinal dengan rumus persentase.
Temuan penelitian – Hasil penelitian menunjukkan dari 30 responden diketahui analisis kualitas layanan terhadap CU Lantang Tipo di Balai Sepuak sebagian besar mempunyai sikap cukup puas 9%, sikap tidak puas sebesar 4%, sikap sangat tidak puas sebesar 0%, sikap sangat puas sebesar 4% dan sikap puas sebesar 3%. berdasarkan hasil penelitian tersebut diartikan kualitas layanan terhadap CU Lantang Tipo di Balai Sepuak adalah cukup puas
COVID-19 Pandemic and Research on the Mediating Role of Absorptive Capacity on the Relationship between Business Analytics Capability and Small-to-Medium-Sized Enterprise Performance
Authors: Holman Benjamin , Whitaker Christine 
Published: January 2022

This initial study's key purpose was to investigate whether absorptive capacity performed a mediating role on the relationship between business analytics capability and small-to-medium-sized enterprises (SMEs) performance in the United States. The study's findings are more relevant now as the COVID-19 pandemic continues to impact small-to-medium-sized enterprise (SME) businesses in the United States. The study derived from the resource-based view approach, the dynamic capabilities dimension perspective, through the theoretical lens of the reconceptualization of absorptive capacity by Zahra and George (2002). The study empirically tested mediation through a series of regressions based on Baron and Kenny (1996). As recent extensions of the resource-based view theory, absorptive capacity and business analytics embody the dynamic capabilities, business intelligence, and knowledge management for modern business firms to align, modify, and reconfigure during a dynamic and volatile global business environment. Throughout the pandemic, it appears businesses have had to continually regain economic ground. This paper is an effort to apply the findings of research on the importance of absorptive capacity and business analytics capability as it pertains to the reality of the COVID-19 pandemic on SMEs. The study contributed to the theoretical body of knowledge on dynamic capabilities by empirically demonstrating how SMEs may manifest improvement in performance in the twenty-first century by utilizing data in collaboration with business analytics at the realized absorptive capacity dimension. In wake of the ongoing COVID-19 pandemic, exploring the research study's findings may provide insight to help SMEs survive during these difficult times, and even thrive, by increasing their absorptive capacity to utilize data analytics effectively.
Keywords: Resource-Based View, Absorptive Capacity, Business Analytics, Dynamic Capabilities, Information Technology, Small-To-Medium-Sized Enterprise (SME), COVID-19
Status of Coral Reefs in Lagonoy Gulf, Eastern Bicol, Philippines with Emphasis on Marine Protected Areas
Authors: Mendoza Antonino B. , Borejon Michael C. , B. Bista Joshua Karl 
Published: January 2022

Status of coral reef health of 8 Marine Protected Areas (MPA), 6 adjacent MPA reefs and 5 regular reefs of Lagonoy Gulf were assessed from December 2017 to August 2018 and compared with previous gulf-wide assessment results in 1994 and 2004. Underwater photo transect (UPT) method was utilized to collect benthic lifeform information and coral point count with excel extensions (CPCe) was used to analyzed benthic data. Results showed that present live coral cover in MPAs are low with 26% as compared to adjacent MPA reef areas (30%) and regular reef stations (33%). A downtrend was noted from 1993 – 2004 with 10% decline of MPA reefs while from 2004 to 2018 decrease was almost 20% and from 1993 to 2018 an average fall of 25% was detected. Overall, Lagonoy Gulf reef health is declining and can be attributed to both natural and fisheries activities, as evidenced by almost 20 typhoons affecting the Region per year with a super typhoon at least every 5-10 years and the heavy dependence of fishing communities on reef fishes respectively. However, non-MPA reefs decline was observed to very minimal as compared for both MPA and adjacent MPA reefs ranging from 1% to 6%. With this, MPA management schemes should be revisited and amended to improve and strengthen MPA governance, direction and strategies.
Risk‐Perceptional and Feedback‐Controlled Response System Based on NO2‐Detecting Artificial Sensory Synapse
Authors: Qian Chuan , Choi Yongsuk , Kim Seonkwon , Kim Seongchan , Choi Young Jin , Roe Dong Gue , Lee Jung Hun , Kang Moon Sung , Lee Wi Hyoung , Cho Jeong Ho 
Published: January 2022

AbstractBio‐inspired artificial neural networks can be used to realize the efficient perception and parallel processing of unstructured data. This paper proposes a feedback‐controlled response system based on a NO2‐detecting artificial sensory synapse, which can process, judge, and react to a varying gas environment. The NO2‐detecting artificial sensory synapse adopts an organic heterostructure involving the charge trapping layer (pentacene) and hole‐conducting layer (copper‐phthalocyanine). The electron‐withdrawing nature of NO2 and its high compatibility with copper‐phthalocyanine induce the retentive behavior of an increase in the conductance at the hole conduction channel when consecutive positive pulses are applied to the gate terminal. The system consists of the artificial sensory synapse and artificial neuron circuits, which can provide systematic responses to varying NO2 conditions, thereby successfully simulating the efficient risk‐response system of biological neural networks. The proposed feedback‐controlled response system can facilitate the development of bionic electronics and artificial intelligence frameworks.
Theory of Chirality Induced Spin Selectivity: Progress and Challenges
Authors: Evers Ferdinand , Aharony Amnon , Bar‐Gill Nir , Entin‐Wohlman Ora , Hedegård Per , Hod Oded , Jelinek Pavel , Kamieniarz Grzegorz , Lemeshko Mikhail , Michaeli Karen , Mujica Vladimiro , Naaman Ron , Paltiel Yossi , Refaely‐Abramson Sivan , Tal Oren , Thijssen Jos , Thoss Michael , van Ruitenbeek Jan M. , Venkataraman Latha , Waldeck David H. , Yan Binghai , Kronik Leeor 
Published: January 2022

AbstractA critical overview of the theory of the chirality‐induced spin selectivity (CISS) effect, that is, phenomena in which the chirality of molecular species imparts significant spin selectivity to various electron processes, is provided. Based on discussions in a recently held workshop, and further work published since, the status of CISS effects—in electron transmission, electron transport, and chemical reactions—is reviewed. For each, a detailed discussion of the state‐of‐the‐art in theoretical understanding is provided and remaining challenges and research opportunities are identified.
Multilayer Reservoir Computing Based on Ferroelectric α‐In2Se3 for Hierarchical Information Processing
Authors: Liu Keqin , Dang Bingjie , Zhang Teng , Yang Zhen , Bao Lin , Xu Liying , Cheng Caidie , Huang Ru , Yang Yuchao 
Published: January 2022

AbstractDynamic physical systems such as reservoir computing (RC) architectures show a great prospect in temporal information processing, whereas hierarchical information processing capability is still lacking due to the absence of advanced multilayer reservoir elements. Here, a stackable reservoir system is constructed based on ferroelectric α‐In2Se3 devices with voltage input and output, which is realized by dynamic voltage division between a ferroelectric field‐effect transistor and a planar device and therefore allows the reservoirs to cascade, enabling multilayer RC. Fast Fourier transformation analysis shows high‐harmonic generation in the first layer as a result of inherent nonlinearity of the reservoir, and progressive low‐pass filtering effect is realized where higher‐frequency components are progressively filtered in deeper‐layer RCs. Time‐series prediction and waveform classification tasks are also demonstrated, serving as evidence for the memory capacity and computing capability of the deep reservoir architecture. This work can provide a promising pathway in exploiting emerging 2D materials and dynamics for advanced neuromorphic computing architectures.
A Biomimetic Human Lung‐on‐a‐Chip with Colorful Display of Microphysiological Breath
Authors: Zhu Yujuan , Sun Lingyu , Wang Yu , Cai Lijun , Zhang Zhuohao , Shang Yixuan , Zhao Yuanjin 
Published: January 2022

AbstractLung‐on‐a‐chip models hold great promise for disease modeling and drug screening. Herein, inspired by the iridescence phenomenon of soap bubbles, a novel biomimetic 3D microphysiological lung‐on‐a‐chip system with breathing visualization is presented. The system, with an array of pulmonary alveoli at the physiological scale, is constructed and coated with structural color materials. Cyclic deformation is induced by regular airflow, resembling the expansion and contraction of the alveoli during rhythmic breathing. As the deformation is accompanied with corresponding synchronous shifts in the structural color, the constructed system offers self‐reporting of the cell mechanics and enables real‐time monitoring of the cultivation process. Using this system, the dynamic relationships between the color atlas and disease symptoms, showing the essential role of mechanical stretching in the phenotypes of idiopathic pulmonary fibrosis, are investigated. These features make this human lung system ideal in biological study, disease monitoring, and drug discovery.
Gold Nanoparticle‐Labeled CRISPR‐Cas13a Assay for the Sensitive Solid‐State Nanopore Molecular Counting
Authors: Liu Li , Xu Zhiheng , Awayda Kamel , Dollery Stephen J. , Bao Mengdi , Fan Jianlin , Cormier Denis , O'Connell Mitchell R. , Tobin Gregory J. , Du Ke 
Published: January 2022

AbstractA gold nanoparticle (AuNP)‐labeled CRISPR‐Cas13a nucleic acid assay is developed for sensitive solid‐state nanopore sensing. Instead of directly detecting the translocation of RNA through a nanopore, the system utilizes non‐covalent conjugates of AuNPs and RNA targets. Upon CRISPR activation, the AuNPs are liberated from the RNA, isolated, and passed through a nanopore sensor. Detection of the AuNPs can be observed as increasing ionic current in the chip. Each AuNP that is detected is enumerated as an event, leading to quantitative of molecular targets. Leveraging the high signal‐to‐noise ratio enabled by the AuNPs, a detection limit of 50 fM before front‐end target amplification is achieved using SARS‐CoV‐2 RNA segments as a Cas13 target. Furthermore, a dynamic range of six orders of magnitude is demonstrated for quantitative RNA sensing. This simplified AuNP‐based CRISPR assay is performed at the physiological temperature without relying on thermal cyclers. In addition, the nanopore reader is similar in size to a smartphone, making the assay system suitable for rapid and portable nucleic acid biomarker detection in either low‐resource settings or hospitals.
Ultra‐Thin GeSe/WS2 Vertical Heterojunction with Excellent Optoelectronic Performances
Authors: Yan Bing , Ning Bo , Zhang Guoxin , Zhou Dahua , Shi Xuan , Wang Chunxiang , Zhao Hongquan 
Published: January 2022

AbstractHeterostructural engineering of atomically thin 2D materials offers an exciting opportunity to fabricate atomically sharp interfaces for optoelectronic devices. Herein, GeSe/WS2 heterojunction devices composed of 2D WS2 (n‐type) and few‐layer GeSe (p‐type), are fabricated by transferring mechanically exfoliated GeSe to chemical vapor deposition (CVD)‐grown WS2. Excellent rectification behavior is observed from the I−V characteristics of the GeSe/WS2 heterojunction devices. The reverse photocurrent increases more rapidly than the forward photocurrent under a 635 nm laser illumination, indicating an effective separation of the photogenerated carriers under a minus bias. A large photocurrent on‐off ratio of 103 at −5 V bias, a high responsivity (Rλ) of 1.1 A W−1, a considerable specific detectivity (D*) of 1.3×1010 Jones, and a high external quantum efficiency (EQE) of 214.8%, are obtained. Owing to the large built‐in potential of the heterojunction, efficient charge transfer is achieved from the abrupt interfaces even though vastly different materials are used in the van der Waals (vdW) heterostructure. A convenient route is demonstrated for the preparation of ultra‐thin GeSe/WS2 vdW heterojunctions. The results reveal great potential of the present GeSe/WS2 vertical heterojunction for future applications in optoelectronics.
Extremely High Power Efficiency Solution‐Processed Orange‐Red TADF OLEDs via a Synergistic Strategy of Molecular and Device Engineering
Authors: Jiang Dehao , Sasabe Hisahiro , Arai Hiroki , Nakao Kohei , Kumada Kengo , Kido Junji 
Published: January 2022

AbstractThe development of high‐performance, solution‐processed, orange‐red organic light‐emitting diodes (OLEDs) based on thermally activated delayed fluorescence (TADF) emitters is a challenging endeavor. In this study, two orange‐red TADF emitters, namely 2DMAC‐DBP‐2tBuCz and 2SPAC‐DBP‐2tBuCz, are developed by a novel donor–acceptor–functional‐group (D‐A‐R) molecular design strategy. This design makes the molecules highly soluble and inhibits concentration quenching of excitons, rendering the emitter suitable for use in devices with high concentration to boost their performance. The solution‐processed, orange‐red OLEDs manufactured in this study achieve a state‐of‐the‐art maximum external quantum efficiency (EQEmax) value of 23.7% and an extremely high maximum power efficiency (PEmax) of 48.8 lm W−1, which is nearly twice higher than the previously reported best value (27.1 lm W−1). Therefore, the collaboration of molecular engineering and sophisticated device design provides a novel method for extremely low power consumption solution‐processed OLEDs.
Targeting Cancer Metabolism Plasticity with JX06 Nanoparticles via Inhibiting PDK1 Combined with Metformin for Endometrial Cancer Patients with Diabetes
Authors: Yang Xiao , Cheng Yuan , Zhou Jingyi , Zhang Lingpu , Li Xingchen , Wang Zhiqi , Yin Shenyi , Zhai LiRong , Huang Ting , Wu Xiaotong , Shen Boqiang , Dong Yangyang , Zhao Lijun , Chi Yujing , Jia Yuanyuan , Wang Jiaqi , He Yijiao , Dong Xiying , Xiao Haihua , Wang Jianliu 
Published: January 2022

AbstractDiabetes is closely related to the occurrence of endometrial cancer (EC) and its poor prognosis. However, there is no effective clinical treatment for EC patients with diabetes (patientEC+/dia+). To explore new therapeutic targets, Ishikawa is cultured with high glucose (IshikawaHG) mimicking hyperglycemia in patientEC+/dia+. Subsequently, it is discovered that IshikawaHG exhibits glucose metabolic reprogramming characterized by increased glycolysis and decreased oxidative phosphorylation. Further, pyruvate dehydrogenase kinase 1 (PDK1) is identified to promote glycolysis of IshikawaHG by proteomics. Most importantly, JX06, a novel PDK1 inhibitor combined metformin (Met) significantly inhibits IshikawaHG proliferation though IshikawaHG is resistant to Met. Furthermore, a reduction‐sensitive biodegradable polymer is adopted to encapsulate JX06 to form nanoparticles (JX06‐NPs) for drug delivery. It is found that in vitro JX06‐NPs have better inhibitory effect on the growth of IshikawaHG as well as patient‐derived EC cells (PDC) than JX06. Additionally, it is found that JX06‐NPs can accumulate to the tumor of EC‐bearing mouse with diabetes (miceEC+/dia+) after intravenous injection, and JX06‐NPs combined Met can significantly inhibit tumor growth of miceEC+/dia+. Taken together, the study demonstrates that the combination of JX06‐NPs and Met can target the cancer metabolism plasticity, which significantly inhibits the growth of EC, thereby provides a new adjuvant therapy for patientsEC+/dia+.
Reticulated Porous Perovskite Structures for Thermochemical Solar Energy Storage
Authors: Pein Mathias , Matzel Luca , de Oliveira Lamark , Alkan Gözde , Francke Alexander , Mechnich Peter , Agrafiotis Christos , Roeb Martin , Sattler Christian 
Published: January 2022

AbstractThe inherent capability of concentrated solar power (CSP) plants for sensible thermal energy storage ensures their continuous operation and is considered their most crucial competitive edge versus other renewable energy sources. The storage density of air‐operated CSP plants can be significantly increased by hybridizing sensible with thermochemical storage of solar heat, exploiting reversible air–solid oxide reduction–oxidation reactions. Thermochemical storage‐relevant‐protocols testing of in‐house manufactured lab‐scale reticulated porous ceramic foams made entirely of CaMnO3 perovskite reveals fully reversible reduction‐oxidation in up to 46 cycles between 300 and 1100 °C under air, without any deterioration of the foams’ structural integrity and exploitable endothermic/exothermic heat effects between 890 and 920 °C linked to an orthorhombic‐to‐cubic phase transition. Dilatometry experiments with CaMnO3 bars under identical cyclic conditions demonstrate the correlation of this phase transition to an increase in the thermal expansion coefficient but nevertheless, complete recovery of the initial specimen dimensions upon completion of a full heat‐up/cooldown redox cycle. The possibility of shaping into sturdy reticulated porous ceramic structures which exhibit complete dimensional reversibility upon cyclic redox operation, combined with the low cost, earth abundance and environmentally benign character of the constituting elements, render such perovskite compositions extremely attractive for the manufacture of large‐scale porous structured objects for exploitation in various thermochemical processes.