bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel finding of intra-genus inhibition of quorum sensing in Vibrio bacteria
Authors: Hoang Huong Thanh , Nguyen Thuy Thu Thi , Do Ha Minh , Nguyen Thao Kim Nu , Pham Hai The 
Published: September 2022

AbstractQuorum sensing is the process by which microbial cells sense and respond to the co-presence of others in their surrounding, through the detection of their autoinducers associated with gene expression regulation and thereby controlling many physiological processes, such as biofilm formation and/or bioluminescence, etc. In Vibrio bacteria, where quorum sensing is relatively well understood with three commonly known autoinducers (HAI-1, AI-2 and CAI-1), both intra-species and inter-species cell–cell communications occur but no inter-Vibrio-species quorum sensing inhibition has been reported. In this study, by screening bacterial isolated from soil and mud samples in a northern province in Vietnam, we discovered a strain that reduced more than 75% of the bioluminescence of a Vibrio harveyi, with evidence showing that such an inhibition might be associated with quorum sensing inhibition. The strain, designated as XTS1.2.9, was identified to be a Vibrio parahaemolyticus bacterium based on its morphological, physiological, biochemical and phylogenetic characteristics. We also tested XTS1.2.9 for its bioluminescence inhibition against different mutants lacking different quorum sensing autoinducers by using plate assays. The results showed that XTS1.2.9 inhibited the bioluminescence of the mutants having sensor 1, especially the one detecting CAI-1, and lacking sensor for AI-2; while it did not inhibit the mutants having only sensor for AI-2 and lacking sensor 1. Therefore, we propose an intra-genus quorum sensing inhibition mechanism involving CAI-1 to explain for such interactions between Vibrio parahaemolyticus and Vibrio harveyi. This phenomenon is reported for the first time and may have certain scientific and application implications.
Increased probability of mood disorders after age-related macular degeneration: a population-based cohort study
Authors: Lee Chia-Yi , Chen Hung-Chi , Huang Jing-Yang , Lai Chi-Chun , Lin Hung-Yu , Yang Shun-Fa , Wu Wei-Chi 
Published: September 2022

AbstractWe aim to investigate the association of mood disorders with age-related macular degeneration (AMD). This retrospective cohort study used data from 2000 and 2016 from National Health Insurance Research Database (NHIRD) in Taiwan. Patients with AMD diagnosis formed the exposed group, and an age- and sex-matched group without AMD served as the nonexposed group. Main outcomes were the incidence of mood disorders including psychological counseling, behavior therapy, sleep or anxiety-related disorders, and major depressive disorders (MDDs) in the exposed and non-exposed groups. The Cox proportional hazard regression analysis was used to evaluate the incidence and adjusted hazard ratio (aHR) of mood disorders. A total of 5916 and 11,832 individuals with and without AMD were enrolled into the exposed and nonexposed groups. There were 1017 (17.19%) and 1366 (11.54%) episodes of mood disorders occurred in the exposed and nonexposed groups, respectively. The aHRs of any psychological counseling, behavioral therapy, sleep or anxiety-related disorders, and MDD were significantly higher in patients with AMD than in those without AMD (all P < 0.05). Besides, patients with dry-AMD, participants aged 50–70 years, and women with AMD had a higher incidence of mood disorders (all P < 0.05) than did non-AMD individuals, patients > 70 years, and women without AMD. In conclusion, AMD occurrence leads to an increased rate of mood disorders, particularly among those with dry-AMD, middle aged participants (aged 50–70), and women.
Piracema: a Phishing snapshot database for building dataset features
Authors: Gomes de Barros Julio Cesar , Revoredo da Silva Carlo Marcelo , Candeia Teixeira Lucas , Torres Fernandes Bruno José , Lorenzato de Oliveira Joao Fausto , Luzeiro Feitosa Eduardo , Pinheiro dos Santos Wellington , Ferraz Arcoverde Henrique , Cardoso Garcia Vinicius 
Published: September 2022

AbstractPhishing is an attack characterized by attempted fraud against users. The attacker develops a malicious page that is a trusted environment, inducing its victims to submit sensitive data. There are several platforms, such as PhishTank and OpenPhish, that maintain databases on malicious pages to support anti-phishing solutions, such as, for example, block lists and machine learning. A problem with this scenario is that many of these databases are disorganized, inconsistent, and have some limitations regarding integrity and balance. In addition, because phishing is so volatile, considerable effort is put into preserving temporal information from each malicious page. To contribute, this article built a phishing database with consistent and balanced data, temporal information, and a significant number of occurrences, totaling 942,471 records over the 5 years between 2016 and 2021. Of these records, 135,542 preserve the page’s source code, 258,416 have the attack target brand detected, 70,597 have the hosting service identified, and 15,008 have the shortener service discovered. Additionally, 123,285 records store WHOIS information of the domain registered in 2021. The data is available on the websitehttps://piracema.io/repository.
Association between phthalate exposure and accelerated bone maturation in Chinese girls with early puberty onset: a propensity score-matched case–control analysis
Authors: Huang Shurong , Su Zhe , Su Huiping , Jiao Yanhua , Su Qiru , Yao Yao , Zhou Li , Zheng Xiuxin , Zhang Xingliang 
Published: September 2022

AbstractEstrogen can promote the acceleration of bone maturation and phthalate esters (PAEs) have estrogen-mimicking effects. We investigated whether PAEs are associated with the acceleration of bone age (BA) in girls with early onset of puberty (EOP). This case–control study enrolled 254 girls with EOP from the Endocrinology Department at Shenzhen Children’s Hospital between December 2018 and August 2019. Ultra-performance liquid chromatography and tandem mass spectrometry were used to analyze the 10 metabolites of PAEs (mPAEs) in urine samples. BA was measured using an artificial intelligence system. BA exceeding the chronological age (CA) by > 2 years (BA-CA ≥ 2 years) was referred to as significant BA advancement. Participants were divided into groups A (BA-CA ≥ 2 years; case group) and B (BA-CA < 2 years; control group). Propensity score matching (PSM) was performed for both groups in a 1:2 ratio with a caliper of 0.25. To identify potential dose–response relationships between PAEs exposure and BA advancement, we grouped the participants after PSM according to the tertiles of the mPAE concentrations. After PSM, 31 and 62 girls in groups A and B were selected. The concentration of Mono-ethyl phthalate (MEP) in group A was significantly higher than in group B (11.83 μg/g vs. 7.11 μg/g, P < 0.05); there was no significant difference in the levels of other mPAEs between the groups. The degree of BA advancement and proportion of significantly advanced BA in the lowest, middle, and highest tertiles of the MEP sequentially increased, as well as in the lowest, middle, and highest tertiles of Mono-(2-ethyl-5-carboxypentyl) phthalate; however, these were only statistically different between the highest and lowest MEP tertiles (both P < 0.05). For the remaining mPAEs, differences in the degree of BA advancement among the lowest, middle, and highest tertiles, as well as differences in the proportion of significantly advanced BA among the lowest, middle, and highest tertiles, were not significant (all P > 0.05). Our findings suggested that MEP was positively associated with BA advancement in girls with EOP. Exposure to PAEs may promote accelerated bone maturation.
Numerical study on the impact of wall structure on the thermal performance of double-channel porous solar wall
Authors: Qi Xuejun , Lin Shuang , Tao Shuyan , Patchigolla Kumar 
Published: September 2022

AbstractWith the improvement of people’s living standards, they have higher requirements for indoor thermal comfort in the cold season. Solar wall utilizing solar energy for heating can reduce carbon emissions and achieve carbon neutrality. In the aspect of solar wall research, the influence of wall structure on the thermal performance of double-channel porous solar wall is limitedly investigated. In fact, the optimization design of wall structure is important for the thermal performance of solar wall and its applications. Therefore, a simplified three dimensional room model is built to study the influence of the wall structure on the thermal performance of porous solar wall by numerical simulation. With this model, different channel spacing and thickness of porous walls were used to determine the optimal design for a double-channel porous solar wall in terms of enhancing the heat storage. Moreover, the influence of the surface emissivity on the characteristics of heating and temperature field of double-channel porous solar wall are studied based on the optimal structure. The CFD simulation results indicate that the optimal structure parameters should include spacing of 0.08 m for channel 1, the porous wall thickness should be 0.08 m, and the air channel 2 spacing should be 0.06 m. The temperature of air channel 1 and air channel 2, the indoor temperature, and the heat storage of porous wall decrease with the increase of the surface emissivity of the porous wall. In order to improve the heat storage performance of double-channel porous solar wall, the outer surface of the porous wall should use a lower emissivity material. The outer surface emissivity of porous wall has a significant impact on the heat storage of the porous wall and little effect on the thermal storage wall. The temperature of porous wall is always higher than that of outdoor environment temperature.
Responsiveness of the new index muscular echotexture in women with metastatic breast cancer: an exercise intervention study
Authors: Escriche-Escuder Adrian , Trinidad-Fernández Manuel , Pajares Bella , Iglesias-Campos Marcos , Alba Emilio , García-Almeida José Manuel , Roldán-Jiménez Cristina , Cuesta-Vargas Antonio I. 
Published: September 2022

AbstractUltrasound imaging texture analyses may provide information on tissue homogeneity changes in metastatic breast cancer (MBC) through second-order analyzes based on the gray-level co-occurrence matrix. This study aimed to analyze the responsiveness and correlations of biomarkers of muscular and fat echotexture after an exercise intervention in women with MBC. A 12-week exercise intervention was conducted in 2019, including aerobic and strength training. Echotexture variables were obtained at baseline and after intervention from the quadriceps (Q) and biceps brachii and brachialis. Mean differences were calculated using the T-Student parametric test for dependent samples of the differences in the means (P = 0.05; 95% CI). Data obtained from 13 MBC women showed significant differences in some echotexture variables after the intervention. QLQ-BR23 questionnaire correlated with several echotexture variables from muscle and subcutaneous fat. PFS-R scale correlated positively with the Q Subcutaneous Fat Non-Contraction Homogeneity (R = 0.43,P < 0.05). Q Muscle Non-Contraction Energy and Q Muscle Non-Contraction Textural Correlation explained 90% of the variance of QLQ-BR23. Some muscle and subcutaneous fat echotexture biomarkers showed good responsiveness after the exercise intervention. Additionally, some muscle and subcutaneous fat variables correlated with QLQ-BR23 and cancer-related fatigue measured by PFS-R scale in MBC patients.Trial registration: NCT03879096
Deep learning-based reconstruction on cardiac CT yields distinct radiomic features compared to iterative and filtered back projection reconstructions
Authors: Chun Sei Hyun , Suh Young Joo , Han Kyunghwa , Kwon Yonghan , Kim Aaron Youngjae , Choi Byoung Wook 
Published: September 2022

AbstractWe aimed to determine the effects of deep learning-based reconstruction (DLR) on radiomic features obtained from cardiac computed tomography (CT) by comparing with iterative reconstruction (IR), and filtered back projection (FBP). A total of 284 consecutive patients with 285 cardiac CT scans that were reconstructed with DLR, IR, and FBP, were retrospectively enrolled. Radiomic features were extracted from the left ventricular (LV) myocardium, and from the periprosthetic mass if patients had cardiac valve replacement. Radiomic features of LV myocardium from each reconstruction were compared using a fitting linear mixed model. Radiomics models were developed to diagnose periprosthetic abnormality, and the performance was evaluated using the area under the receiver characteristics curve (AUC). Most radiomic features of LV myocardium (73 of 88) were significantly different in pairwise comparisons between all three reconstruction methods (P < 0.05). The radiomics model on IR exhibited the best diagnostic performance (AUC 0.948, 95% CI 0.880–1), relative to DLR (AUC 0.873, 95% CI 0.735–1) and FBP (AUC 0.875, 95% CI 0.731–1), but these differences did not reach significance (P > 0.05). In conclusion, applying DLR to cardiac CT scans yields radiomic features distinct from those obtained with IR and FBP, implying that feature robustness is not guaranteed when applying DLR.
Acute multiple toxic effects of Trifloxystrobin fungicide on Allium cepa L.
Authors: Macar Oksal , Kalefetoğlu Macar Tuğçe , Yalçın Emine , Çavuşoğlu Kültiğin 
Published: September 2022

AbstractTrifloxystrobin (TFS) is a strobilurin-type fungicide that should be investigated due to its risks to non-targeted organisms. The goal of this study was to assess the susceptibility of Allium cepa L. to TFS in a multi-pronged approach. For 72 h, 0.2 g/L, 0.4 g/L and 0.8 g/L doses of TFS were administered to A. cepa bulbs and the control group was treated with tap water. The toxic effects of TFS were tested, considering physiological, cytogenetic, biochemical and anatomical analyses. TFS delayed growth by reducing the rooting ratio, root elongation and weight increase. Following TFS treatments, mitotic index (MI) scores decreased, while the formation of micronucleus (MN) and chromosomal aberrations (CAs) ascended. CAs types induced by TFS were listed according to their frequency as fragment, vagrant chromosome, sticky chromosome, uneven distribution of chromatin, bridge, nucleus with vacuoles, reverse polarization and irregular mitosis. TFS provoked an increment in superoxide dismutase (SOD) and catalase (CAT) enzyme activities as well as an accumulation of malondialdehyde (MDA). Meristematic cells of A. cepa roots treated with TFS had various anatomical damages, including damaged epidermis, flattened cell nucleus, damaged cortex and thickness in the cortex cell wall. All damages arising from TFS treatments exhibited dose-dependency. The findings of the present study revealed the serious toxicity of TFS in a non-targeted plant. It should not be neglected to evaluate the potential hazards of TFS with different toxicity tests.
Van der Waals interfaces in multilayer junctions for ultraviolet photodetection
Authors: Xie Shihong , Shiffa Mustaqeem , Shiffa Mujahid , Kudrynskyi Zakhar R. , Makarovskiy Oleg , Kovalyuk Zakhar D. , Zhu Wenkai , Wang Kaiyou , Patanè Amalia 
Published: September 2022

AbstractDevelopments in semiconductor science have led to the miniaturization and improvement of light detection technologies for many applications. However, traditional pn-junctions or three-dimensional device geometries for detection of ultraviolet (UV) light are still limited by the physical properties of the semiconductors used, such as the small penetration depth of UV light in silicon. Van der Waals (vdW) semiconductors and their pn-junctions can offer an alternative solution due to their optical properties and thin pn-junction region. Here, we report on a multi-layer junction that combines single layer graphene and vdW semiconductors (p-GaSe and n-In2Se3) with strong optical absorption in the UV range. The junctions have broadband spectral response (0.3-1.0 μm) and high photoresponsivity under forward and reverse bias, or without any externally applied voltage. The photoresponse differs from that of a traditional pn-junction diode as it is governed by charge transport across thin layers and light-current conversion at three vdW interfaces (e.g. the graphene/GaSe, GaSe/In2Se3 and In2Se3/graphene interfaces). The type-II band alignment at the GaSe/In2Se3 interface and electric field at the three vdW interfaces are beneficial to suppress carrier recombination for enhanced photoresponsivity (up to ~102 A/W) and detectivity (up to ~1013 Jones), beyond conventional UV-enhanced silicon detection technology.
Topological triplet-superconductivity in spin-1 semimetal
Authors: Sim GiBaik , Park Moon Jip , Lee SungBin 
Published: September 2022

AbstractSuperconductivity in topological semimetals gives a new paradigm of unconventional superconductors. Their exotic gap structures and topological properties have fascinated searching for material realizations and applications. In this work, we focus on a triple point semimetal where quasiparticle excitations, triple point fermions, carry the effective integer spin-1 in two distinct valleys. Our work demonstrates that the triple point fermion stabilizes inter-valley s-wave spin-triplet pairing. This is due to Fermi statistics, which strictly forbids the formation of inter-valley s-wave spin-singlet pairings. This feature is clearly distinct from the BCS and other multi-band superconductors. We find that two distinct inter-valley s-wave spin-triplet superconductors are allowed which in principle can be controlled by tuning the chemical potential: time-reversal symmetric (sz) state with topologically protected nodal lines and time-reversal broken (sx + isy) state with topologically protected Bogoliubov Fermi surfaces. Our study provides guidance in searching for spin-triplet superconductivity.
A special issue of Essays in Biochemistry on cancer stem cells
Authors: Ying Fan , Lee Terence Kin Wah 
Published: September 2022

Abstract
Cancer stem cells (CSCs) are subpopulation of cells within the tumor bulk, which leads to tumor recurrence and therapeutic resistance. Identification of specific CSC targets for detection and efficient cancer therapy are the major hurdles in this research field. In this decade, basic researchers and clinicians made every effort to overcome these challenges to target CSCs using different approaches. This special issue includes a varied collection of review articles with comprehensive discussion on the complexity of CSC heterogeneity, signaling pathways regulating the behaviors of CSCs, the therapeutic resistance mechanism of CSCs, and therapeutic targets against CSCs. These review articles shed light on current advances in understanding of CSC biology.
Distance estimates for AGB stars from parallax measurements
Authors: Andriantsaralaza M. , Ramstedt S. , Vlemmings W. H. T. , De Beck E. 
Published: September 2022

Context. Estimating the distances to asymptotic giant branch (AGB) stars using optical measurements of their parallaxes is not straightforward because of the large uncertainties introduced by their dusty envelopes, their large angular sizes, and their surface brightness variability.
Aims. This paper aims to assess the reliability of the distances derived with Gaia DR3 parallaxes for AGB stars, and provide a new distance catalogue for a sample of ∼200 nearby AGB stars.
Methods. We compared the parallaxes from Gaia DR3 with parallaxes measured with maser observations with very long baseline interferometry (VLBI) to determine a statistical correction factor for the DR3 parallaxes using a sub-sample of 33 maser-emitting oxygen-rich nearby AGB stars. We then calculated the distances of a total of ∼200 AGB stars in the DEATHSTAR project using a Bayesian statistical approach on the corrected DR3 parallaxes and a prior based on the previously determined Galactic distribution of AGB stars. We performed radiative transfer modelling of the stellar and dust emission to determine the luminosity of the sources in the VLBI sub-sample based on the distances derived from maser parallaxes, and derived a new bolometric period-luminosity relation for Galactic oxygen-rich Mira variables.
Results. We find that the errors on the Gaia DR3 parallaxes given in the Gaia DR3 catalogue are underestimated by a factor of 5.44 for the brightest sources (G <  8 mag). Fainter sources (8 ≤ G <  12) require a lower parallax error inflation factor of 2.74. We obtain a Gaia DR3 parallax zero-point offset of −0.077 mas for bright AGB stars. The offset becomes more negative for fainter AGB stars. After correcting the DR3 parallaxes, we find that the derived distances are associated with significant, asymmetrical errors for more than 40% of the sources in our sample. We obtain a PL relation of the form Mbol = (− 3.31 ± 0.24) [log P − 2.5]+(−4.317 ± 0.060) for the oxygen-rich Mira variables in the Milky Way. A new distance catalogue based on these results is provided for the sources in the DEATHSTAR sample.
Conclusions. The corrected Gaia DR3 parallaxes can be used to estimate distances for AGB stars using the AGB prior, but we confirm that one needs to be careful when the uncertainties on parallax measurements are larger than 20%, which can result in model-dependent distances and source-dependent offsets. We find that a RUWE (re-normalised unit weight error) below 1.4 does not guarantee reliable distance estimates and we advise against the use of only the RUWE to measure the quality of Gaia DR3 astrometric data for individual AGB stars.
Immunsuppression und Risiken bei Gravidität nach Nierentransplantation
Authors: Clement Deborah , Stangl Manfred , Thorban Stefan , Matevossian Edouard 
Published: September 2022

ZUSAMMENFASSUNGNach einer Nierentransplantation (NTx) steigt die Chance einer erfolgreichen Schwangerschaft für die Transplantatempfängerinnen deutlich, die Geburtsraten sind bei diesen Frauen ähnlich hoch wie in der Normalbevölkerung. 1963 wurde bereits über die erste erfolgreiche Gravidität nach NTx berichtet. Allerdings können zahlreiche Risikofaktoren wie nephrologische Grunderkrankungen das Zeitintervall zwischen Transplantation und Konzeption, Infektionen, Diabetes, Bluthochdruck, Übergewicht, eingeschränkte Transplantatfunktion, Proteinurie, Präeklampsie und insbesondere die Einnahme von Immunsuppressiva den Schwangerschaftsverlauf und die Transplantatfunktion belasten. Jede Schwangerschaft nach NTx sollte interdisziplinär von einem erfahrenen Team begleitet werden. Unter nahezu idealen Voraussetzungen ist die Schwangerschaft als nicht riskant einzustufen, das individuelle Risiko ist allerdings nicht quantifizierbar. Die Zahl an Sectios, Präeklampsie, Frühgeburtlichkeit und Untergewicht des Kindes ist allerdings signifikant erhöht. Sind die Bedingungen für Frauen nach einer Nierentransplantation nicht ideal für eine Schwangerschaft, können Konfliktsituationen entstehen, in denen ethische Prinzipien wie Autonomie, Schadensvermeidung, Wohltätigkeit und Gerechtigkeit diskutiert werden müssen. In der vorliegenden Arbeit werden Studien und Erfahrungen zu diesem Thema ausgewertet sowie Empfehlungen und Risiken für die Patientin und ihr Kind zusammengefasst, entsprechend den Vorgaben der Studiengruppe European Renal Best Practice.
Qualität der Nachbehandlungsempfehlungen in
unfallchirurgischen Entlassungsbriefen
Authors: Schmidt J. , Schmidt I. 
Published: September 2022

ZusammenfassungIm Rahmen einer qualitativen Querschnittsuntersuchung wurde die Qualität
der Nachbehandlungsempfehlungen von Arztbriefen aus unfallchirurgischer
Erstbehandlung in Traumazentren überprüft. Bei einem Drittel der
Briefe fanden sich keine wesentlichen Informationen zur Nachbehandlung, in einem
weiteren Drittel allgemeine Hinweise. Überregionale Traumazentren
schnitten deutlich besser ab. Es wird der Vorschlag gemacht, die Erstellung von
Arztbriefen bereits in die studentische Ausbildung zu integrieren.