bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental investigations for variability quantification of vibration response of short(−natural)‐fiber‐reinforced polypropylene
Authors: Proy J. , Massa F. , Notta‐Cuvier D. , Lauro F. , Tison T. , Spingler G. 
Published: September 2022

AbstractShort‐fiber‐reinforced‐materials are widely used in industry today. In this paper, microstructure and modal analyses are performed on short‐glass‐fiber‐reinforced polypropylene (PPGF) and short‐natural‐fiber‐reinforced polypropylene (PPNF), to study possible links between the first natural frequency and fibers' orientation and quantify the associated variability. In view of this, different specimens were tested with clamped‐free boundary conditions. The microstructural analysis, performed with micro‐computed tomography studies fibers' properties in injection‐molded plates. This study shows the importance of considering real fibers' orientation for modal predictions.
Partition testing for real‐world evidence studies
Authors: Cafri Guy , Wood Jennifer , Gagne Joshua 
Published: September 2022

AbstractTraditional approaches to hypothesis testing in comparative post‐approval safety and effectiveness studies of medical products are often inadequate because of a limited scope of possible inferences (e.g., superiority or inferiority). Often there is interest in simultaneously testing for superiority, equivalence, inferiority, non‐inferiority, and non‐superiority, which can be achieved using a partition testing framework. Partition testing only requires selection of an equivalence margin and calculation of a two‐sided Wald confidence interval. In addition to permitting a broader range of inferences, the strengths of the approach include: mitigating publication bias, avoiding use of a clinically irrelevant nil hypothesis, and more transparent and impartial appraisal of the clinical importance of a study's findings by pre‐specifying an equivalence margin. However, a challenge in implementing the approach can be the process for identifying an equivalence margin. The methodology is illustrated using a published study of the safety of Ondansetron for the off‐label treatment of nausea and vomiting during pregnancy. Applying the method to the study results would have led to a conclusion that women exposed to Ondansetron in comparison to those that are not, are equivalent with respect to risk of cardiac malformations and oral clefts. These conclusions are more in line with the magnitude of the observed effects than the conclusions resulting from a traditional inferiority/superiority testing conducted by the study authors.
Insight into the role of debris in the formation of polytetrafluoroethylene film via molecular dynamic simulation of debris adhesion
Authors: Niu Xiaoxing , Zhou Shidong , Pan Deng , Zhao Yuanliang , Li Lei 
Published: September 2022

AbstractIn this paper, the role of debris in the formation of polytetrafluoroethylene (PTFE) film was investigated using the molecular dynamic simulation of debris adhesion. The results indicate that the internal structure of PTFE debris could not be changed easily because of the strong cohesion of PTFE debris. Debris will be adhered on Fe surface by the strong adhesion between Fe surface and debris. With the formation of transfer film, the adhesion between thin debris and Fe surface decreases gradually and will be lower than that of debris and PTFE matrix. The difference of the adhesion between PTFE debris and friction pairs will induce the quite different adsorption behavior of thin debris and thick debris. With the formation of stable transfer film, thin debris tends to be adhered on PTFE matrix and thick debris tends to be adhered on Fe surface. This will reduce the interfacial adhesion of friction pairs. The interactive influence between the adsorption of debris and the evolution of transfer film is beneficial to the decrease of COF and the wear of PTFE.
Radiographic paradoxical response in metastatic castrate‐resistant prostate cancer (mCRPC) managed with new generation anti‐androgens: a retrospective analysis
Authors: Alamiri Jamal , Britton Cameron J. , Ahmed Mohamed E. , Andrews Jack R. , Higa Julianna L. , Dundar Ayca , Karnes R. Jeffrey , Kwon Eugene , Lowe Val J. , Kendi Ayse T. , Bold Michael S. , Pagliaro Lance C. 
Published: September 2022

AbstractBackgroundProstatic specific antigen (PSA) has well‐recognized limitations as a marker for treatment response and disease progression. Post hoc analysis of the PREVAIL trial reported 24.5% of chemotherapy naïve metastatic castration‐resistant prostate cancer (mCRPC) patients on enzalutamide had radiographic progression on conventional imaging with nonrising PSA. In this study, we sought to study the discordance of imaging with PSA kinetics in mCRPC patients on second generation anti‐androgens (SGA) post‐chemotherapy using combined conventional imaging, and new generation imaging in the form of C‐11 choline positron emission tomography/computed tomography (C[11] choline PET/CT) scan.MethodsWe retrospectively reviewed the medical records of 123 patients with mCRPC treated with SGA (Abiraterone or Enzalutamide) after docetaxel between 2016 and 2019. Patients underwent PSA testing, and C[11] choline PET/CT scan at baseline level before starting treatment with SGA, then every 3–6 months as part of their follow up evaluation. Loss of response to SGA was defined by increase in corrected maximum standardized uptake value (SUVmax) of pretreatment lesions on C‐11 Choline PET/CT, and/or development of new lesions. Suspicious new lesions were confirmed by biopsy and/or conventional imaging.ResultsWe identified 123 mCRPC patients who received SGA (Abiraterone, n = 106; Enzalutamide, n = 17) after docetaxel. Median duration of therapy was 13.9 months (interquartile range: 8.75–21.14). Approximately 43% (n = 53) of subjects in this study exhibited an increase in choline avidity while on SGA. Of this group, 60.4% of patients experienced a parallel rise in PSA (Group‐A), whereas 39.6% displayed a paradoxical response (PR) (Group‐B), defined as increased choline avidity combined with stable or down‐trending PSA. Median PSA at time of increase in choline avidity was 3.1 ng/ml for Group‐A, and 1.3 ng/ml for Group‐B (p = 0.0176). Median SUVmax was similar in both groups (4.9 for Group‐A, 4.6 for Group‐B; p = 0.6072). The median time for increase in choline avidity was 9.5 versus 3.9 months for Group‐A versus Group‐B, respectively (Log‐Rank = 0.0063).ConclusionNearly 40% of mCRPC patients placed on SGA post docetaxel chemotherapy will exhibit paradoxical responses to therapy, therefore, warranting close follow up with imaging. C‐11 choline PET/CT imaging is a useful tool that can help in early predication of disease progression or treatment failure.
Iatrogenic empyema secondary to the malposition of a nasogastric tube
Authors: Chan Daryl Emery Chee Yeow , Mansour Verena , Ting Aaron , Gupta Saurabh , Frankel Anthony 
Published: September 2022

AbstractBlind NGT insertion can lead to tube misplacement into the respiratory tract. This can lead to multiple pulmonary complications including lung injury, pneumothorax, pneumonia, empyema and diaphragmatic injury. We present the case of an 80 year‐old female who required an NGT insertion for severe oropharyngeal dysphagia from an acute stroke. Her admission was complicated by multiple pneumothoraces from repeated insertions, as well as the unusual complication of a recurrent nasogastric feeding‐related empyema requiring multiple intercostal chest drain insertions for drainage. This case highlights the importance of careful NGT insertion and placement with imaging confirmation before use.
Metagenomic signature and total petroleum hydrocarbons distribution in a crude oil contaminated ultisol remediated with biochar–humus sediment slurry
Authors: Offiong Nnanake‐Abasi O. , Inam Edu J. , Fatunla Opeyemi K. , Ofon Utibe A. , Abraham Nsikak A. , Essien Joseph P. 
Published: September 2022

AbstractUltisols are peculiar soils generally known for their poor nutrient status. When contaminated, remediation of ultisols present the additional challenge of nutrient and ecological restoration. In this study, we report the distribution of total petroleum hydrocarbons (TPHs) in a simulated crude oil‐contaminated ultisol amended with biochar (BC)/humus sediment (HS) slurry. We also investigated the microbial abundance, diversity, and enzyme expression in the treatment medium that gave the optimum remediation results. We recorded lowest TPH levels in remediant amendments with BC produced at 700°C. Majority of the OTUs (27.96%) found in the remediated ultisol belonged to Firmicutes (27.96%), Proteobacteria (25.88%), and Gemmatimonadetes (23.32%) while enzymes (AlkM, alkB, AlmA, PRM, cP450, MMO/AMO subunits A, B, and C, and Genes ssuD, ssuC, dszC, dszA, and dszB) encountered in this study were expressed mainly by bacteria belonging to the order Actinomycetales and Bulkhoderiales.
Using analytical equations to represent nonlinear relationships
Authors: Ríos‐Ocampo Juan , Gary Michael Shayne 
Published: September 2022

AbstractTable functions, also referred to as graphical functions, provide a powerful and user‐friendly way to represent nonlinear relationships between variables in system dynamics (SD) models. However, in many cases modelers may benefit from using analytical equations to represent nonlinear relationships for model sensitivity testing and also for communicating with researchers in other fields and disciplines. We propose six analytical equations that can be used to represent many of the nonlinear relationships commonly formulated using table functions in SD models. Specifically, this article provides guidance on using the generalized logistic function, the exponential function, the modified exponential function, the quadratic function, the logarithmic function and the power function to replace existing table functions. Importantly, we also present a version of each equation that includes an interior reference point. We demonstrate how to apply these analytical equations in SD models by replacing the table functions in the original World Dynamics model. We also provide a Python script to help implement our recommended procedure for incorporating the six analytical equations into models and a Vensim macro for each analytical equation. © 2022 The Authors. System Dynamics Review published by John Wiley & Sons Ltd on behalf of System Dynamics Society.
Surface evolution of InP substrates at the frontier between deoxidation and dissolution in HCl solutions
Authors: Béchu Solène , Aureau Damien , Etcheberry Arnaud 
Published: September 2022

Surfaces of InP substrates with different crystallographic orientations are investigated when facing HCl solutions. The immersion of InP(100) in HCl solutions with a wide concentrations range showed that the frontier between deoxidation and dissolution is around 6 m, with a morphological destructuration. However, no chemical evolutions are noticed even at high concentrations. Similar observations were performed with other crystallographic orientations (polycrystalline and InP(111) substrates), with topographic surface modifications but no chemical ones.
The thoracoacromial trunk: a detailed analysis
Authors: Bonczar Michał , Gabryszuk Kamil , Ostrowski Patryk , Batko Jakub , Rams Daniel Jakub , Krawczyk-Ożóg Agata , Wojciechowski Wadim , Walocha Jerzy , Koziej Mateusz 
Published: September 2022

Abstract
Purpose
The thoracoacromial trunk (TAT) originates from the second part of the axillary artery and curls around the superomedial border of the pectoralis minor, subsequently piercing the costocoracoid membrane. Knowledge about the location, morphology, and variations of the TAT and its branches is of great surgical importance due to its frequent use in various reconstructive flaps.

Methods
A retrospective study was conducted to establish anatomical variations, their prevalence, and morphometric data on TAT and its branches. The results of 55 consecutive patients who underwent neck and thoracic computed tomography angiography were analyzed. A qualitative evaluation of each TAT was performed.

Results
A total of 15 morphologically different TAT variants were initially established. The median length of the TAT was set at 7.74 mm (LQ 3.50; HQ 13.65). The median maximum diameter of the TAT was established at 4.19 mm (LQ 3.86; HQ 4.90). The median TAT ostial area was set to 13.97 mm (LQ 11.70; HQ 18.86). To create a heat map of the most frequent location of the TAT, measurements of the relating structures were made.

Conclusion
In this study, the morphology and variations of the branching pattern of the TAT were presented, proposing a new classification system based on the four most commonly prevalent types. The prevalence of each branch arising directly from the TAT was also analyzed. It is hoped that the results of the present anatomical analysis can help to minimize potential complications when performing plastic or reconstructive procedures associated with TAT.
Does attentional suppression occur at the level of perception or decision-making? Evidence from Gaspelin et al.’s (2015) probe letter task
Authors: Kerzel Dirk , Renaud Olivier 
Published: September 2022

AbstractVisual attention is often inadvertently captured by salient stimuli. It was suggested that it is possible to prevent attentional capture in some search tasks by suppressing salient stimuli below baseline. Evidence for attentional suppression comes from a probe task that was interleaved with the main search task. In the probe task of Gaspelin et al. (Psychol Sci 26(11):1740–1750, 2015. https://doi.org/10.1177/0956797615597913), letters were shown on the stimuli of the search display and participants had to identify as many letters as possible. Performance was found to be worse for letters shown on the distractor compared to non-salient non-target stimuli, suggesting that distractor processing was suppressed below baseline. However, it is unclear whether suppression occurred at the level of perception or decision-making because participants may have reported letters on the distractor less frequently than letters on nontargets. This decision-level bias may have degraded performance for letters on distractor compared to nontarget stimuli without changing perception. After replicating the original findings, we conducted two experiments where we avoided report bias by cueing only a single letter for report. We found that the difference between distractor and nontarget stimuli was strongly reduced, suggesting that decision-level processes contribute to attentional suppression. In contrast, the difference between target and non-target stimuli was unchanged, suggesting that it reflected perceptual-level enhancement of the target stimuli.
Pathology associated with Tripaphylus Richiardi, 1878 infection (Copepoda: Sphyriidae) in wild-caught Australian blackspot sharks, Carcharhinus coatesi (Whitley, 1939), off northern Australia
Authors: Barton Diane P. , Kirke Amy , Johnson Grant , Boxshall Geoff 
Published: September 2022

AbstractFemale specimens of the newly described mesoparasitic copepod Tripaphylus squidwardi (Sphyriidae), collected from the Australian blackspot shark, Carcharhinus coatesi, off northern Australia were examined histologically. The ‘encapsulated’ head of the copepod was found in the ventral musculature of the throat of the shark. The head of the copepod was surrounded by a tissue capsule of unknown origin. There were signs of chronic inflammation associated with the infection, although there appeared to be no effect on the health of the shark.
Efficacy and safety analysis of bortezomib-based triplet regimens sequential lenalidomide in newly diagnosed multiple myeloma patients
Authors: Zhou Qiaolin , Xu Fang , Wen Jingjing , Yue Jing , Zhang Ya , Su Jing , Liu Yiping 
Published: September 2022

AbstractThe aim of this study is to analyze the efficacy and safety of sequential therapy with bortezomib-based triplet regimens without lenalidomide (PXD, including VTD, PAD, and VCD) followed by continuous lenalidomide and dexamethasone (Rd) or bortezomib and dexamethasone (Vd) treatment. The main objective is to evaluate the advantages of PXD followed by Rd compared to the combinations of bortezomib–lenalidomide–dexamethasone (VRd) in newly diagnosed multiple myeloma (NDMM). Fifty-eight nontransplant NDMM patients who were admitted to our department from 2017 to 2019 were included in this study. Bortezomib-based triplet regimens were initially selected and followed by Rd or Vd as continuous treatment once the patients achieved partial remission (PR) or better response. The efficacy and safety of the patients were observed. The Rd continuous treatment cohort was compared with historical data from the EVOLUTION trial on continuous VRd treatment. In our cohort, the overall survival rate was 100%, and progression-free survival (PFS) was 38.5% after a median of 19 (4–36) cycles of Rd continuous therapy was applied. During the follow-up period, the best outcome assessments achieved were 53.8% complete response (CR) and 84.6% excellent partial response (VGPR). A total of 23.1% had grade 3–4 or higher drug-related adverse reactions, mainly hematological toxicity, and no patients died of adverse reactions. Compared with the Vd group, the Rd group had a better PFS and VGPR rate (2-year PFS: 92.3% vs. 56.3%, P = 0.002; 3-year PFS: 69.2% vs. 8.0%, P < 0.001; VGPR: 84.6% vs. 69.2%, P = 0.02). No significant differences were found in ORR (100% vs. 92.3%) or CR (53.8% vs. 35.7%, P = 0.082). Compared with the EVOLUTION study, patients in the Rd group had a more advanced disease stage (stage III rate of 40% vs. 19%, P = 0.039) and worse physical status (KPS 50–60 rate of 25.0% vs. 2.0%, P = 0.000). However, a higher proportion of ORR (100% vs. 73.0%, P < 0.001), VGPR or better (75.0% vs. 32.0%, P < 0.001), and PFS at 12 months (90.0% vs. 68%, P = 0.011) were achieved. Sequential administration of bortezomib-based triplet regimens without lenalidomide as an initial therapy followed by Rd as a continuous treatment may not be inferior to VRd for first-line treatment in NDMM patients.
Compressive strength evaluation of thin occlusal veneers from different CAD/CAM materials, before and after acidic saliva exposure
Authors: Ille Codruța , Moacă Elena-Alina , Pop Daniel , Goguță Luciana , Opriș Carmen , Pîrvulescu Ioana Ligia , Avram Liane , Faur Andrei , Jivănescu Anca 
Published: September 2022

AbstractIn the present study are depicted valuable observations for practitioners, obtained from an in vitro study which aims to evaluate the compressive strength of occlusal veneers fabricated from 3 type of restorative materials, before and after 1 month of acidic artificial saliva exposure (pH = 2.939). In this context, 90 extracted human molars were prepared to receive computer-aided design/computer-aided manufacturing (CAD/CAM) occlusal veneers. The restorative materials considered in this study were: Cerasmart; Straumann Nice and Tetric CAD. The occlusal veneers were designed, milled and cemented with an adhesive dual-cure resin cement. From all the extracted human molars, only sixty specimens were immersed in acidic artificial saliva, for 1 month, at 37 °C ± 1 °C and part of this specimens were also thermo-cycled, between 5 and 55 °C ± 2 °C, before compressive strength test. The results showed a lower compressive strength for both the samples exposed to acidic artificial saliva as well as for the samples exposed to acidic artificial saliva and thermo-cycled. Scanning electron microscopy (SEM) showed that after compressive strength, all the specimens non-exposed to acidic artificial saliva, present extensive cracks formation at the surface of the restorations, and after exposure to acidic artificial saliva for 1 month, the surface damage was characterized by longitudinal and profound fractures of the restoration, as well as the fracture of the tooth structure. Between CAD/CAM materials tested, nanoceramic resin shows more favorable fracture patterns, both before and after acidic artificial saliva exposure.
Untere Einkommensgruppen noch gezielter entlasten
Authors: Kritikos Alexander S. , Schulze Düding Johanna , Morales Octavio , Priem Maximilian 
Published: September 2022

AbstractPrices for energy and food are currently rising extraordinarily sharply. Households with low net incomes in particular are being burdened by the price increases, in some cases dramatically. According to current inflation forecasts, price increases for the lowest-income ten percent would mean a burden of 5.3 percent of their net household income in 2022. Since the low-income deciles cannot compensate for the additional expenditure by reducing their savings rate or possible reserves, nor can they restrict their consumption behavior to a corresponding extent since they primarily consume goods and services for basic needs, it is essential to provide relief for these households. The measures already adopted by the German government are easing the burden on citizens, but they are not enough to compensate for the additional burden on lower-income households. Further aid packages should provide targeted and efficient relief for households at the lower half of the income distribution.
EU-Pläne für einen CO2-Grenzausgleich
Authors: Söllner Fritz 
Published: September 2022

ZusammenfassungDas CO2-Grenzausgleichssystem der EU kann die Verlagerung der Produktion bzw. von Emissionen in Drittländer nur zum Teil verhindern. Es wird sehr hohe Kosten verursachen, nicht zu einer kosteneffizienten Emissionsreduktion beitragen und kaum Anreize für Drittländer schaffen, ihre Emissionen zu reduzieren. Das System ist nicht WTO-konform und wird deshalb Anlass zu handelspolitischen Streitigkeiten und Konflikten geben, unter denen vor allem Deutschland mit seinen hohen Exportüberschüssen zu leiden haben wird. Es spricht vieles dafür, das vorgeschlagene System nicht zu realisieren und die Wettbewerbsnachteile europäischer Unternehmen weiter durch die teilweise kostenlose Zuteilung von ETS-Zertifikaten auszugleichen.
Finanzierung einer kapitalgedeckten Altersgrundsicherung über die Erbschaftsteuer
Authors: Löhr Dirk 
Published: September 2022

ZusammenfassungDie umlagefinanzierte gesetzliche Rentenversicherung kann angesichts der demografischen Entwicklung eine auskömmliche Versorgung im Alter bald nicht mehr sichern. Indem die Bürger:innen über eine kapitalgedeckte Alterssicherung am Unternehmensvermögen mittelbar beteiligt werden, könnte die Rentenlücke zumindest teilweise geschlossen werden. Das Unternehmensvermögen sollte bei einem neuen Reformanlauf auch vollständig in die Erbschaftsteuer einbezogen werden; dabei darf aber der Fortbestand der Unternehmen nicht gefährdet werden. Die Erbschaftsteuer auf Unternehmensvermögen könnte dabei als Finanzierungsquelle für eine kapitalgedeckte Altersgrundsicherung dienen.
Betriebliche Bündnisse sichern Beschäftigung
Authors: Seifert Hartmut , Pusch Toralf 
Published: September 2022

ZusammenfassungZu den betrieblichen Bündnissen liefert dieser Beitrag einige empirische Ergebnisse aus einer repräsentativen Befragung von Betriebsräten. Dabei werden die vereinbarten Inhalte mit denen der Finanzkrise 2009 verglichen, um zu prüfen, ob sich bestimmte Grundmuster aufgrund erfahrungsgesättigter Praxis wiederholen, aber auch neue Spezifika angesichts veränderter Problemkonstellationen herausbilden. Schließlich wird diskutiert, welche Schlussfolgerungen im Falle eines möglichen neuerlichen Konjunkturabschwungs zu ziehen sind.
Verschwendung der Jahresendausgaben im öffentlichen Sektor: Replik und Erwiderung
Authors: Schwarting Gunnar , Siemroth Christoph 
Published: September 2022

ZusammenfassungIn der Juniausgabe 2022 veröffentlichte der Wirtschaftsdienst einen Aufsatz mit dem Titel „Dezemberfieber senken: Vermeidung von verschwenderischen Jahresendausgaben“ von Christoph Siemroth. Gunnar Schwarting vertritt in einer Replik eine andere Auffassung, im Anschluss erläutert Christoph Siemroth seinen Standpunkt in einer Erwiderung.