bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factors of Cardiovascular Death after Venous Thromboembolism: Results from a Prospective Cohort Study
Authors: Noumegni Steve Raoul , Mansourati Vincent , Tromeur Cécile , Mao Raphael Le , Hoffmann Clément , Moigne Emmanuelle Le , Nasr Bahaa , Gentric Jean-Christophe , Guegan Marie , Poulhazan Elise , Bressollette Luc , Lacut Karine , Couturaud Francis , Didier Romain 
Published: June 2022

Abstract
Background Cardiovascular deaths (CVDTs) are more frequent in patients with venous thromboembolism (VTE) than in the general population; however, risk factors associated with this increased risk of CVDT in patients with VTE are not described.
Methods To determine the risk factors of CVDT in patients with VTE from a multicenter prospective cohort study, Fine and Gray subdistribution hazard models were conducted.
Results Of the 3,988 included patients, 426 (10.7%) died of CVDT during a median follow-up of 5 years. The risk factors of CVDT after multivariate analyses were: age of 50 to 65 years (vs. <50 years, hazard ratio [HR]: 3.22, 95% confidence interval [CI]: 1.67–6.62), age >65 years (vs. <50 years, HR: 7.60, 95% CI: 3.73–15.52), cancer-associated VTE (vs. transient risk factor-related VTE, HR: 1.73, 95% CI: 1.15–2.61), unprovoked VTE (vs. transient risk factor-related VTE, HR: 1.42, 95% CI: 1.02–2.00), past tobacco use (vs. never, HR: 1.43, 95% CI: 1.06–1.94), current tobacco use (vs. never, HR: 1.87, 95% CI: 1.15–3.01), hypertension (HR: 2.11, 95% CI: 1.51–2.96), chronic heart failure (HR: 2.28, 95% CI: 1.37–3.79), chronic respiratory failure (HR: 1.72, 95% CI: 1.02–2.89), and atrial fibrillation (HR: 1.67, 95% CI: 1.06–2.60). The risk of CVDT was significantly reduced with direct oral anticoagulants (vs. vitamin-K antagonists) and with longer duration of treatment (>3 months).
Conclusion Risk factors of CVDT after VTE include some traditional cardiovascular risk factors and other risk factors that are related to characteristics of VTE, and patients' comorbidities.
Beyond the dikes: an institutional perspective on governing flood resilience at the Port of Rotterdam
Authors: Punt Eline , Monstadt Jochen , Frank Sybille , Witte Patrick 
Published: June 2022

AbstractSeaports, infrastructural nodes in global supply chains and production processes, are vulnerable to flood risks: they are crisis-prone critical infrastructure (CI) systems. However, the governance of their flood resilience involves many different private and public actors in a complex institutional environment and there is no scholarly consensus about how resilience can be successfully governed. We investigate the governance of flood resilience at the Port of Rotterdam (PoR) from an institutional perspective, by studying institutional arrangements for flood resilience within and across vertical, horizontal and territorial dimensions to elucidate the strengths and ongoing challenges of shaping the port’s flood resilience. We conducted semi-structured expert interviews (n = 17) and an analysis of policy documents and legislation (n = 33) relating to flood risk management and CI protection. We find that the institutional design for flood resilience in the Netherlands consists of a complex matrix of responsibilities, capacities and plans. While coordination is visible in the shared visions and strategies for flood resilience developed at different policy levels and domains, we find fragmentation and persisting institutional challenges, including siloed governance approaches, knowledge gaps and blurred distribution of responsibilities; these are significant barriers to enhancing flood resilience for CIs and port–city relationships.
Coordination in the courtroom
Authors: Kytö Merja 
Published: June 2022

Abstract
Previous research has shown that clausal and phrasal uses of and pattern in ways characteristic of different text types in both Present-day and early English. Speech-based text types such as witness depositions and trial records are likely to show higher rates of clausal uses than written-based texts such as science and history writing. The present study turns to the uses of and in a unique resource, the records from the Salem witchcraft trials in New England (1692–1693), comprising a range of speech-related and written-based text categories. To enable comparisons between early American English and British English usage, comparative material is drawn from the Helsinki Corpus and the Corpus of English Dialogues 1560–1760.
Dialect in early African American plays
Authors: Kautzsch Alexander 
Published: June 2022

Abstract
The sources for the historical reconstruction of African American English (AAE) are manifold, ranging from ex-slave narratives and interviews with hoodoo doctors to blues lyrics, and letters authored by semi-literates. The present article looks into the representation of AAE in a further source, early plays (1858–1938), and investigates non-standard morpho-syntactic features found in these imagined instances of AAE speech. A helpful tool for this task is the list of 235 features used in the World Atlas of Varieties of English (WAVE). The results will be compared to the WAVE features found in the more traditional sources of Earlier AAE speech, which ultimately tackles the question of how close the dialect used in these plays matches non-invented Earlier AAE.
EKF-based positioning study of a mobile robot with McNamee wheels
Authors: Xu Jiahui , Liu Gang , Liu Jinhao , Lv Zhiyong , Gao Song 
Published: June 2022

Abstract
This paper focuses on the localization of a McNamee wheel mobile robot, which has six states of motion and more complex kinematic equations than a normal mobile robot using a McNamee wheel. In this paper, the kinematic model of the McNamee wheel mobile robot is developed, and the extended Kalman filter algorithm (EKF) is used to fuse the inertial measurement unit (IMU) and the wheel encoder odometer information to estimate the position state of the mobile robot and to eliminate the environmental noise and the effect of wheel slippage. By comparing the estimated and calculated values with the actual trajectory, the proposed method is able to eliminate environmental effects and correctly reflect the posture information of the McNamee wheel mobile robot. It is demonstrated that the proposed method can eliminate the environmental influence and correctly reflect the posture information of the McNamee wheel mobile robot.
Distribution Grid Resource Business Center Integrating Dynamic Migration Algorithm and Lightweight System
Authors: Zhu Haipeng , Zhao Lei , Qin Kun , Li He , Wang Di , Zhang Shiwei 
Published: June 2022

Abstract
The existing power system does not have a unified grid resource management model. The basic data of equipment assets cannot be stored, managed, and maintained in a unified manner. The production systems of different departments are developed by different manufacturers at different times, which leads to the problem of production data silos and high maintenance costs. To solve this problem, a grid resource business middle platform based on State grid-corporation public data model (SG-CIM, CIM) model is designed in this paper. Firstly, the concept and core technology of the middle platform in the power grid resource business are introduced. Then a dynamic data migration strategy based on the FA algorithm is proposed. Finally, the model based on SG-CIM and the application scenario of power transmission and distribution are built and its effectiveness is analyzed.
Algorithm of ant colony optimization (ACO) for 3D variation traveling salesman problem
Authors: Riabko A V , Zaika O V , Kukharchuk R P , Vakaliuk T A , Hordiienko I V 
Published: June 2022

Abstract
The article discusses the solution of the spatial traveling salesman problem (TSP 3D variation) using Ant Colony Optimization (ACO). The traveling salesman problem considers n bridges and a matrix of pairwise distances between them. It is necessary to find such an order of visiting cities so that the total distance traveled was minimal, each city was visited exactly once and the salesman returned to the city from which he began his route. In the TSP 3D variation problem, each “city” has 3 coordinates x, y, z. The analysis of the main methods of solving, in particular, the metaheuristic algorithms to which ACO belongs, is performed. At each iteration of these methods, a new solution of the problem is built, which is based not on one, but several solutions of the population. The ACO uses an idea that is based on collecting statistical information about the best solutions. The program code is implemented in MATLAB. During computational experiments, various network topologies were randomly generated, and the number of iterations at which the optimal cycle was achieved was recorded. The execution time of the code for the TSP 3D task is almost the same as the execution time of TSP 2D. The results can be used for spatial tasks of the salesman (TSP 3D-variation), which arise in the process of 3D printing, planning UAV trajectories (UAV) in mountain conditions or multi-story urban development, road planning in multi-story buildings.
Mathematical model of the base unit of the biotechnical system as a type of edge devices
Authors: Nikitchuk T M , Vakaliuk T A , Andreiev O V , Korenivska O L , Osadchyi V V , Medvediev M G 
Published: June 2022

Abstract
The rapid development of computer biometrics over the past 2-3 decades is largely due to the development and widespread introduction into clinical practice of new methods of studying the human body health, including pulse methods. It is possible to judge changes in hemodynamic characteristics, heart rate and blood flow rate in the studied part of the body based on the parameters of the pulse wave signal. At the same time, the physical processes of formation of the pulse wave shape have not been fully studied, although the number of biophysical models of blood circulation is quite significant. The development of such a model will allow to effectively apply modern developments in digital signal processing to the pulse wave and increase its diagnostic value. Qualitative model of pulse signal can be entrusted to the development of the base unit of the biotechnical system as a type of edge devices. The work is devoted to the improvement of methods of rapid diagnosis of the cardiovascular system based on the analysis of model pulsegrams. An adequate mathematical model of the pulse wave, which corresponds to real pulse signals in different states of the human body and contains mathematical relationships between the main parameters of pulsegrams, has been refined. The algorithm of express diagnostics with the established criteria of the analysis of pulsograms is offered.
Data mining of the healthcare system based on the machine learning model developed in the Microsoft azure machine learning studio
Authors: Klochko O V , Gurevych R S , Nagayev V M , Yu Dudorova L , Zuziak T P 
Published: June 2022

Abstract
This article presents data mining, which is based on the methods of mathematical statistics and machine learning, describes the features of applying regression analysis methods in the machine learning systems. The developed machine learning model includes the regression analysis modules based on the Bayesian linear, artificial neural network, decision tree, decision forest, and linear regressions. In the process of applying this machine learning model, using the mentioned algorithms, the corresponding regression models were constructed and their comparative analysis was performed, the results were analyzed. The results obtained indicate the feasibility of using data mining in the medical research using machine learning systems. The presented methods can serve as a basis for strategic development of a new directions of the medical data processing and decision-making in this field. We have identified the prospects for further research aimed at applying data mining methods to the healthcare system, namely, clustering, classification, anomaly detection.
The effect of the flipped classroom model on quality of the students‘ performance in biology education in high school
Authors: Zupanec V , Vlasic D , Pribicevic T , Lazarevic T 
Published: June 2022

Abstract
This study investigated the effectiveness of flipped classroom model (FC) and traditional classroom model (TC) in Biology on the quality of the high school students‘ performance. The research sample consisted of a total of 280 first grade high school students in Novi Sad, Serbia. The students in the experimental group learned Biology topic through the FC model, whereas the students in the control group were taught the same topic by the TC model. The instruments used in the research (the pretest and the posttest) contained the questions belonging to three different levels of cognitive learning according to the revised Bloom’s Taxonomy. The results indicated that students that were instructed by the flipped classroom in Biology performed better on the posttest as a whole, and in solving the tasks of all three levels of knowledge (remembering, understanding, and applying) than those instructed by the traditional teaching method. On the basis of the obtained results, a grater implementation of FC model in high school biology teaching is recommended as a way of improving the quality of biology teaching in our and other countries over the world and the level of our students‘ digital competencies.
A model of learning the online course “Creative Thinking through Learning Elementary Maths”
Authors: Achkan V V , Vlasenko K V , Chumak O O , Sitak I V , Kovalenko D A 
Published: June 2022

Abstract
The article considers the development of the online educational model “Creative Thinking through Learning Elementary Maths” and the results of the effciency to implement this course for students of the specialization “Mathematics” while learning Elementary Mathematics. The research represents the development of learning materials for the online course posted in free access on the educational platform “Higher School Mathematics Teacher”. The course components (theoretical, practical, and feedback) are focused on the organization of motivated and consistent students’ activity; open and integrative Rich tasks of three levels of complexity. The course participants’ activity, focused on the recognition, classification, solution, creation of Rich tasks, encourages the formation of the main components of creative thinking that include a problem statement, fluency, flexibility, originality, and elaboration. The first version of the course materials was improved following course users’ wishes, and then the effciency of online course education was checked using an experiment. The analysis of results of the experiment allows concluding about the effciency of the developed model of learning an online course.
STEM education in the context of improving the science and mathematics literacy of pupils
Authors: Hrynevych L M , Khoruzha L L , Rudenko N M , Proshkin V V 
Published: June 2022

Abstract
The article considers the problem of STEM education in the context of improving the quality of science and mathematics literacy of pupils. The results of the monitoring study conducted by the “OsvitAnalityka” Analytical Center of Borys Grinchenko Kyiv University in cooperation with the Kyiv City Educational Agency and the Ukrainian Center for Educational Quality Assessment are presented. The state of formation of science and mathematical literacy of pupils as the ability to apply knowledge to solve practical problems for the implementation of STEM education has been established. Examples of practice-oriented integrated tasks in geography, chemistry, biology and physics that reveal the possibilities of STEM education are given. The success of the implementation of individual tasks, which involved subject integration and the use of knowledge in practice is analyzed. The most important factors influencing the quality of STEM education are highlighted: professional level of teachers, material and technical and educational-methodical support, motivation of pupils, practice-oriented content of education. As a result of the monitoring study, recommendations were prepared for general secondary education institutions for further implementation of STEM education.
Incorporation of upcycling techniques into technology education
Authors: Shuhailo Ya V , Derkach T M , Shpetna A V , Ustenko T 
Published: June 2022

Abstract
By surveying 95 students studying design and technology in the light industry, the problems in mastering upcycling technologies were explored, and ways to overcome them were outlined. The analysis of existing problems is carried out at three levels - personal perception of upcycling, the formation of relevant skills and knowledge and lack of experience in scaling personal expertise to a business startups level. All respondents are roughly divided into those who practice upcycling frequently and those who do it occasionally. Another 15% of respondents did not decide on their preferences. Respondent attitude, control of behaviour, and behavioural intentions are the most influential factors that encourage upcycling. The influence of social factors, perceived habits and the presence of facilitating conditions is more moderate. Interviewed students have a poor understanding of the benefits of upcycling. Competence for creativity, which is key to mastering upcycling techniques, is absent in educational and professional programs in technology and design. Several examples of possible changes in curricula from 4 disciplines aimed at the formation of creativity are given. The main reasons that complicate the scaling of acquired skills and knowledge in developing business startups with upcycling are analysed. An example of a designed startup is given.
Association of statin pretreatment with presentation characteristics, infarct size and outcome in older patients with acute coronary syndrome: the Elderly ACS-2 trial
Authors: Toso Anna , Morici Nuccia , Leoncini Mario , Villani Simona , Ferri Luca A , Piatti Luigi , Grosseto Daniele , Bossi Irene , Sganzerla Paolo , Tortorella Giovanni , Cacucci Michele , Ferrario Maurizio , Tondi Stefano , Ravera Amelia , Bellandi Francesco , Cavallini Claudio , Antonicelli Roberto , De Servi Stefano , Savonitto Stefano 
Published: June 2022

Abstract

Background
prior statin treatment has been shown to have favourable effects on short- and long-term prognosis in patients with acute coronary syndrome (ACS). There are limited data in older patients. The aim of this study was to investigate the association of previous statin therapy and presentation characteristics, infarct size and clinical outcome in older patients, with or without atherosclerotic cardiovascular disease (ASCVD), included in the Elderly-ACS 2 trial.

Methods
data on statin use pre-admission were available for 1,192 of the 1,443 patients enrolled in the original trial. Of these, 531 (44.5%) were already taking statins. Patients were stratified based on established ASCVD and statin therapy. ACS was classified as non-ST elevation or ST elevation myocardial infarction (STEMI). Infarct size was measured by peak creatine kinase MB (CK-MB). All-cause death in-hospital and within 1 year were the major end points.

Results
there was a significantly lower frequency of STEMI in statin patients, in both ASCVD and No-ASCVD groups. Peak CK-MB levels were lower in statin users (10 versus 25 ng/ml, P &lt; 0.0001). There was lower all-cause death in-hospital and within 1 year for subjects with ASCVD already on statins independent of other baseline variables. There were no differences in all-cause death for No-ASCVD patients whether or not on statins.

Conclusions
statin pretreatment was associated with more favourable ACS presentation and lower myocardial damage in older ACS patients both ASCVD and No-ASCVD. The incidence of all-cause death (in-hospital and within 1 year) was significantly lower in the statin treated ASCVD patients.
Plasma ceramides independently predict all-cause mortality in men aged 85+
Authors: Strandberg Timo E , Kivimäki Mika , Urtamo Annele , Jyväkorpi Satu , Laaksonen Reijo 
Published: June 2022

AbstractBackgroundassessing cardiovascular and mortality risk with conventional biomarkers is challenging in oldest-old due to multimorbidity and polypharmacy. Ceramides are bioactive lipids shown to predict mortality in late middle-aged cohorts.Objectiveto assess whether plasma ceramides have independent prognostic value for mortality among oldest-old (85+).Designlongitudinal cohort study (Helsinki Businessmen Study, HBS) with a 3.5-year follow-up.Setting and subjectssurvivors of HBS (125 men born in 1919–1934) visited the clinic for laboratory and clinical examination.Methodsfunctional status including physical (short physical performance battery) and Montreal Cognitive Assessment (MoCA) cognitive performance was assessed and laboratory examinations included a large set of biomarkers. Plasma ceramide concentration (Cer(d18:1/16:0)) was measured using a targeted liquid chromatography–tandem mass spectrometry assay. Mortality was retrieved from national registers.Resultsmedian age was 88 years, two-thirds had multimorbidity and 59% were on statin treatment. During the follow-up, 22 (18%) men died. In a model adjusted for variables associated with mortality in the whole cohort at P &lt; 0.20 (log glucose, SPPB, MoCA and statin use), Cer(d18:1/16:0) as a continuous trait was associated with increased mortality: hazard ratio (HR) per 1 SD 1.64 (95% confidence interval [CI] 1.23–2.18). Compared with the bottom tertile of Cer(d18:1/16:0), HR of mortality was 5.44-fold (95% CI 1.17–25.3) in the top tertile.Conclusionsthese data raise the hypothesis that plasma ceramide concentrations and especially Cer(d18:1/1:60) may offer a clinically useful biomarker to evaluate prognosis in very old age. Such biomarkers are needed for geriatrics, where multimorbidity and pharmacotherapies, such as statins are prevalent hampering assessment of prognosis using conventional methods.