bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mediation in juvenile justice: a perspective assessment
Authors: Savchik Kseniia Vladimirovna 
Published: January 2025

The Russian legislator is currently following international trends that determine the development of restorative justice for minors, the application of the principles of humanization and liberalization of criminal responsibility and punishment. The Russian criminal procedure provides for separate mechanisms that allow the release from criminal liability and punishment, in particular, they include compulsory measures of educational influence and the possibility of reconciliation with the victim in a criminal case. The subject of the study is individual legal norms that establish the specifics of mediation in Russian legal reality while mentioning the used foreign experience; scientific literature on this topic. The purpose of the work is to consider the potential possibility of introducing the mediation into the Russian criminal process in the administration of juvenile justice. The methods used include general scientific (analysis, synthesis, system) and private scientific, among which a special place is given to the formal legal one. The relevance of this author's research is due to the ongoing scientific discussions on this topic, while the voiced points of view are contradictory. The scientific novelty of the research is associated with the conducted critical analysis of a large number of author's points of view, on the basis of which the author formulated and justified his own conclusions. In the end, the author comes to the conclusion that despite the possible positive impact of mediation for resolving legal conflicts, its use in juvenile justice is more rational in relation to persons who have not reached the age of criminal responsibility, and it is more expedient to be guided by existing norms in the criminal process. Consequently, changes in the criminal procedure legislation in this part are not required.
Adaptive error feedback regulator problem for 1‐D anti‐stable wave equation with distributed harmonic disturbance
Authors: Li Zhiyuan , Jin Feng‐Fei , Guo Wei 
Published: January 2022

SummaryIn this article, we are concerned with the error feedback regulator design for a one‐dimensional anti‐stable wave equation with harmonic reference signal and distributed disturbance. By the tracking error of the left end displacement, we first introduce a transport equation and a transformation to transform the original wave system to an auxiliary system, where the displacement at the left end is a scaling of the tracking error of the original system. Then an adaptive error‐based observer is designed by using the tracking error to estimate the state of the auxiliary system and unknown amplitudes of the harmonic disturbance and reference signal. Next we propose an observer‐based error feedback controller to regulate the tracking error to zero asymptotically and keep all the states uniformly bounded. Finally some numerical results are presented to illustrate the effectiveness of the controller.
MIMO system identification using common denominator and numerators with known degrees
Authors: Fazzi Antonio , Grossmann Benjamin , Mercère Guillaume , Markovsky Ivan 
Published: January 2022

SummaryIn system identification, prior knowledge about the model structure may be available. However, imposing this structure on the identified model may be nontrivial. A new discrete‐time linear time‐invariant identification method is presented in the article that imposes prior knowledge of the degree of the common denominator of the system's transfer function matrix and the degrees of the numerators. First, a method is outlined for the solution in case of exact data. Then, this method is extended for noisy data in the output error setting. An initial estimate obtained by a subspace method is improved by a structured low‐rank approximation method. The performance of the method imposing the structure is compared on simulated data with the performance of classical identification methods that do not impose the structure.
Kirigami‐Inspired Biodesign for Applications in Healthcare
Authors: Brooks Anne Katherine , Chakravarty Sudesna , Ali Maryam , Yadavalli Vamsi K 
Published: January 2022

AbstractMechanically flexible and conformable materials and integrated devices have found diverse applications in personalized healthcare as diagnostics and therapeutics, tissue engineering and regenerative medicine constructs, surgical tools, secure systems, and assistive technologies. In order to impart optimal mechanical properties to the (bio)materials used in these applications, various strategies have been explored—from composites to structural engineering. In recent years, geometric cuts inspired by the art of paper‐cutting, referred to as kirigami, have provided innovative opportunities for conferring precise mechanical properties via material removal. Kirigami‐based approaches have been used for device design in areas ranging from soft bioelectronics to energy storage. In this review, the principles of kirigami‐inspired engineering specifically for biomedical applications are discussed. Factors pertinent to their design, including cut geometry, materials, and fabrication, and the effect these parameters have on their properties and configurations are covered. Examples of kirigami designs in healthcare are presented, such as, various form factors of sensors (on skin, wearable), implantable devices, therapeutics, surgical procedures, and cellular scaffolds for regenerative medicine. Finally, the challenges and future scope for the successful translation of these biodesign concepts to broader deployment are discussed.
Restriction‐In‐Motion of Surface Ligands Enhances Photoluminescence of Quantum Dots—Experiment and Theory
Authors: Fang Justin M. , Basu Sayan , Li Mingda , Shih Kuo‐Chih , Wang Jun , Cotlet Mircea , Wang Xudong , Zhao Jing , Mountziaris T. J. , LoTurco Joseph J. , Nieh Mu‐Ping 
Published: January 2022

AbstractThe relationship between emission and ligand restriction of a series of ZnSe/ZnS quantum dots (QDs) encapsulated in nanoparticles is investigated systematically via experiments and quantum theory. The QDs have a ZnSe core and a ZnS shell, capped with hydrophobic ligands (triotylphosphine oxide/hexadecylamine), allowing them to be entrapped in a model biomembrane, bicelle, made of zwitterionic dipalmitoyl and dihexanoyl phosphatidylcholines and charged dipalmitoyl phosphatidylglycerol. Enhanced photoluminescence is observed upon encapsulation, depending on the QD‐to‐lipid ratio. Transmission electron microscopy and small‐angle X‐ray scattering confirm that QDs are preferably situated at the rim of bicellar discs. A simplified quantum dissipation heat‐bath theory is proposed to correlate the enhancement with slower nonradiative processes caused by the restriction‐in‐motion (RIM) of the surface ligands. However, Förster resonance energy transfer due to QD aggregation counteracts the effect.
Spectral Changes by Dye Sensitized Solar Modules Influence the Pigment Composition and Productivity of Arthrospira maxima and Increase the Overall Energy Efficiency
Authors: Borella Lisa , Vesce Luigi , Mariani Paolo , Barichello Jessica , Di Carlo Aldo , Trivellin Nicola , Sforza Eleonora 
Published: January 2022

AbstractThe integration of semi‐transparent photovoltaics (PVs) with photobioreactors (PBRs) is a promising strategy to increase photoconversion efficiency, ensuring simultaneous electricity and algal biomass production. In this study, Arthrospira maxima is cultivated in an integrated system with a dye‐sensitized solar module (DSSM) to the front of the PBR to assess the possible advantages for biomass and phycocyanin production. The application of the DSSM does not influence biomass production, with the remarkable advantage of producing additional electric energy. However, an acclimation of pigment is observed, as DSSM causes a change in the transmitted light spectrum. Further experiments are conducted to investigate the effect of light quality using monochromatic light‐emitting diodes (LEDs) as controls. Phycocyanin‐targeted wavelengths exhibit a major impact on biomass growth and pigment productivity: low intensity enhanced process efficiency, suggesting that low light is preferable to enhance culture performance with respect to white light. The application of third‐generation PVs is only potentially advantageous if the transmission spectra of the module color and its aperture area are carefully designed. The application of monochromatic LEDs on PBRs also highlights the importance of properly managing the operative conditions to avoid energy losses.
Estimation of Lithium‐Ion Battery State of Charge for Electric Vehicles Using an Adaptive Joint Algorithm
Authors: Sakile Rajakumar , Sinha Umesh Kumar 
Published: January 2022

AbstractAs a new means of transportation, electric vehicles (EVs) have a lot of potential. On the other hand, EVs that employ lithium‐ion batteries face certain difficulties in forecasting the battery's health and remaining useful life. This paper uses the adaptive joint algorithm approach to calculate the battery's online parameters and accurate state of charge (SOC). To establish the battery online parameters, the forgetting factor recursive least square (FFRLS) technique is utilized, and the extended Kalman filter (EKF), unscented Kalman filter (UKF) are employed to estimate accurate SOC. Compared to the EKF/UKF method, the joint algorithm (FFRLS‐UKF) approach produces better results. The results are validated using the urban dynamometer driving schedule cycle and the ECE extra‐urban driving cycle (low powered vehicles) to determine the performance of the proposed algorithm. The error of the estimated SOC has fallen from 3.3% to 2%. The proposed adaptive joint algorithm has substantially improved the system's accuracy and provides better results than the EKF/UKF technique. Furthermore, the random variable noise is also supplied to the test data to ensure that the proposed method is robust.
Volatile Solid Additive‐Assisted Sequential Deposition Enables 18.42% Efficiency in Organic Solar Cells
Authors: Qin Jianqiang , Yang Qianguang , Oh Jiyeon , Chen Shanshan , Odunmbaku George Omololu , Ouedraogo Nabonswendé Aïda Nadège , Yang Changduk , Sun Kuan , Lu Shirong 
Published: January 2022

AbstractMorphology optimization of active layer plays a critical role in improving the performance of organic solar cells (OSCs). In this work, a volatile solid additive‐assisted sequential deposition (SD) strategy is reported to regulate the molecular order and phase separation in solid state. The OSC adopts polymer donor D18‐Cl and acceptor N3 as active layer, as well as 1,4‐diiodobenzene (DIB) as volatile additive. Compared to the D18‐Cl:N3 (one‐time deposition of mixture) and D18‐Cl/N3 (SD) platforms, the D18‐Cl/N3(DIB) device based on DIB‐assisted SD method exhibits a finer phase separation with greatly enhanced molecular crystallinity. The optimal morphology delivers superior charge transport and extraction, offering a champion power conversion efficiency of 18.42% with significantly enhanced short‐circuit current density (Jsc) of 27.18 mA cm−2 and fill factor of 78.8%. This is one of the best performances in binary SD OSCs to date. Angle‐dependent grazing‐incidence wide‐angle X‐ray scattering technique effectively reveals the vertical phase separation and molecular crystallinity of the active layer. This work demonstrates the combination of volatile solid additive and sequential deposition is an effective method to develop high‐performance OSCs.
Three‐Dimensional Triptycene‐Functionalized Covalent Organic Frameworks with hea Net for Hydrogen Adsorption
Authors: Yu Chengyang , Li Hui , Wang Yujie , Suo Jinqun , Guan Xinyu , Wang Rui , Valtchev Valentin , Yan Yushan , Qiu Shilun , Fang Qianrong 
Published: January 2022

AbstractOwing to the finite building blocks and difficulty in structural identification, it remains a tremendous challenge to elaborately design and synthesize three‐dimensional covalent organic frameworks (3D COFs) with predetermined topologies. Herein, we report the first two cases of 3D COFs with the non‐interpenetrated hea net, termed JUC‐596 and JUC‐597, by using the combination of tetrahedral and triangular prism building units. Due to the presence of triptycene functional groups and fluorine atoms, JUC‐596 exhibits an exceptional performance in the H2 adsorption up to 305 cm3 g−1 (or 2.72 wt%) at 77 K and 1 bar, which is higher than previous benchmarks from porous organic materials reported so far. Furthermore, the strong interaction between H2 and COF materials is verified through the DFT theoretical calculations. This work represents a captivating example of rational design of functional COFs based on a reticular chemistry guide and demonstrates its promising application in clean energy storage.
Mechanism of the Bifunctional Multiple Product Sesterterpene Synthase AcAS from Aspergillus calidoustus
Authors: Quan Zhiyang , Hou Anwei , Goldfuss Bernd , Dickschat Jeroen S. 
Published: January 2022

AbstractThe multiproduct chimeric sesterterpene synthase AcAS from Aspergillus calidoustus yielded spirocyclic calidoustene, which exhibits a novel skeleton, besides five known sesterterpenes. The complex cyclisation mechanism to all six compounds was investigated by isotopic labelling experiments in combination with DFT calculations. Chemically synthesised 8‐hydroxyfarnesyl diphosphate was converted with isopentenyl diphosphate and AcAS into four oxygenated sesterterpenoids that structurally resemble cytochrome P450 oxidation products of the sesterterpene hydrocarbons. Protein engineering of AcAS broadened the substrate scope and gave significantly improved enzyme yields.
COG6‐CDG: Novel variants and novel malformation
Authors: Cirnigliaro Lara , Bianchi Paolo , Sturiale Luisa , Garozzo Domenico , Mangili Giovanna , Keldermans Liesbeth , Rizzo Renata , Matthijs Gert , Fiumara Agata , Jaeken Jaak , Barone Rita 
Published: January 2022

AbstractBackgroundDeficiency of Conserved Oligomeric Golgi (COG) subunits (COG1–8) is characterized by both N‐ and O‐protein glycosylation defects associated with destabilization and mislocalization of Golgi glycosylation machinery components (COG‐CDG). Patients with COG defects present with neurological and multisystem involvement and possible malformation occurrence. Eighteen patients with COG6‐CDG (COG6 mutations) were reported to date. We describe a patient with COG6‐CDG with novel variants and a novel clinical feature namely a congenital recto‐vaginal fistula.MethodsIn‐depth serum N‐ and O‐glycosylation structural analyses were conducted by MALDI‐TOF mass spectrometry. COG6 variants were identified by a gene panel and confirmed by Sanger sequencing.ResultsThis female newborn presented with facial dysmorphism, distal arthrogryposis and recurrent stool discharges per vaginam. A double‐contrast barium‐enema X‐ray study revealed a dehiscence (approximately 5 mm) at the anterior wall of the rectal ampoule communicating with the vagina consistent with a recto‐vaginal fistula. She had developmental delay, corpus callosum dysgenesis, liver and gastrointestinal involvement, hyperthermia episodes and early demise. Serum N‐ and O‐glycosylation analyses pointed to a profound Golgi disarrangement. We identified two novel variants in COG6: a deletion of 1 bp mutation c.823delA creating a shift in the reading frame and a premature stop codon and a 3 bp deletion (c.1141_1143delCTC) producing an in‐frame deletion of 1 amino acid.ConclusionThe congenital recto‐vaginal fistula is a rare type of anorectal malformation that, to our knowledge, has not been reported in patients with a COG6 defect nor in patients with other COG defects. This study broadens COG6‐CDG genetic landscape and spectrum of malformations.
Minimally invasive transoral robotic surgery for hiloparenchymal submandibular stone: Technical note on Flex Robotic System
Authors: Capaccio Pasquale , Riva Giuseppe , Cammarota Raffaella , Gaffuri Michele , Pecorari Giancarlo 
Published: January 2022

AbstractFlex Robotic System allows a minimally invasive approach for transoral removal of submandibular salivary stones.
A Graphite∥PTCDI Aqueous Dual‐Ion Battery
Authors: Kim Keun‐il , Tang Longteng , Muratli Jesse M. , Fang Chong , Ji Xiulei 
Published: January 2022

AbstractA full cell chemistry of aqueous dual‐ion battery (DIB) was reported, comprising the graphite cathode and 3,4,9,10‐perylenetetracarboxylic diimide (PTCDI) as the anode. This DIB employed a mixture aqueous electrolyte: 5 m tributylmethylammonium (TBMA) chloride plus 5 m MgCl2, where [MgCl3]− and TBMA+ serve as the charge carriers for cathode and anode of the DIB, respectively. This novel full cell exhibited a specific capacity of around 41 mAh g−1 based on the total active mass of both electrodes with an average operation voltage of 1.45 V and stable cycling for 400 cycles.
Bioproduction of Natural Phenethyl Acetate, Phenylacetic Acid, Ethyl Phenylacetate, and Phenethyl Phenylacetate from Renewable Feedstock
Authors: Sekar Balaji Sundara , Li Xirui , Li Zhi 
Published: January 2022

AbstractNatural phenethyl acetate (PEA), phenylacetic acid (PAA), ethyl phenylacetate (Et‐PA), and phenethyl phenylacetate (PE‐PA) are highly desirable aroma chemicals, but with limited availability and high price. Here, green, sustainable, and efficient bioproduction of these chemicals as natural products from renewable feedstocks was developed. PEA and PAA were synthesized from l‐phenylalanine (l‐Phe) via novel six‐ and five‐enzyme cascades, respectively. Whole‐cell‐based cascade biotransformation of 100 mm l‐Phe in a two‐phase system (aqueous/organic: 1 : 0.5 v/v) containing ethyl oleate or biodiesel as green solvent gave 13.6 g L−1 PEA (83.1 % conv.) and 11.6 g L−1 PAA (87.1 % conv.), respectively. Coupled fermentation and biotransformation approach produced 10.4 g L−1 PEA and 9.2 g L−1 PAA from glucose or glycerol, respectively. The biosynthesized PAA was converted to natural Et‐PA and PE‐PA by esterification using lipases with ethanol or 2‐phenylethanol derived from sugar, affording 2.7 g L−1 Et‐PA (83.1 % conv.) and 4.6 g L−1 PE‐PA (96.3 % conv.), respectively.
Multilevel controller‐assisted intrinsically modified ant colony optimization heuristic‐based load‐balancing model for mega cloud infrastructures
Authors: P Govardhan , P Srinivasan 
Published: January 2022

SummaryThe exponential rise in decentralized computing demands has made cloud computing an inevitable technical need; however, under exceedingly high load dynamism, ensuring service level agreement (SLA) has remained a challenge. Despite of the fact that heuristic‐driven VM migration or load‐balancing methods are effective towards quality of service (QoS) and reliable cloud services, the major existing solutions ignore the issues of local minima and convergence and hence undergo SLA violation (SLAV). Moreover, most of the existing methods are designed as a reactive scheduling concept that often results into delayed scheduling and hence SLAV or QoS compromise. To alleviate such issues, in this paper, a robust intrinsically modified evolutionary computing‐driven dynamic load‐balancing model (intrinsically modified ant colony system [IMACS]) is proposed for mega cloud infrastructures. To address aforesaid issues, IMACS employs stochastic prediction‐based overload detection, followed by SLA‐sensitive VM selection and IMACS for load balancing. In IMACS, the use of stochastic prediction‐based overload detection method enabled timely hotspot detection and hence improved proactive decision ability. Moreover, it applies minimum migration time‐sensitive VM selection concept that too helped in guaranteeing load balancing without undergoing downtime or SLAV. To improve VM migration, unlike classical heuristic methods, we designed IMACS with multitype population, adaptive pheromone update, adaptive pheromone diffusion, and coevolution concept, which not only helped in reducing the search space and allied computation but also enabled time‐efficient scheduling decision. The overall proposed model was realized in sync with two controllers named local controller and global controller. Here, the first controller collects the real‐time VM and VM manager (VMM) information which is used to detect overloaded host and the VM to be migrated. While the global controller is designed with IMACS to exploit the information from local controller to execute QoS‐sensitive VM migration. The proposed IMACS‐driven load‐balancing model was realized with CloudSim platform were simulating it over 800 number of independent VMs, each encompassing autonomous task, the performance was analyzed in terms of SLAV, number of migrations, SLA per active host, and energy consumption. Simulation results revealed that the proposed model exhibits 20% higher migration, while retaining almost 19% better SLA in comparison to the other state‐of‐art methods like genetic algorithm or classical ant colony system‐based load‐balancing methods. IMACS exhibited 30% higher host shutdown signifying better energy efficiency (15% lower power consumption).
An effective double gene knock‐in strategy using small‐molecule L755507 in the medaka fish (Oryzias latipes)
Authors: Murakami Yu , Kobayashi Toru 
Published: January 2022

SummaryHomology‐directed repair (HDR)‐mediated genome editing has become a powerful method for altering chromosomal sequences in a seamless and accurate manner. However, the low efficiency of HDR in most cells hinders the establishment of desired strains harboring accurately modified genomes. To enhance HDR‐mediated knock‐in events, we explored two approaches, namely low‐temperature incubation and chemical compound administration using medaka embryos after microinjection. We validated the performance of each method by calculating the knock‐in efficiencies according to the expression area of fluorescent protein in the embryos. The in vivo assay indicated that the reduction in temperature did not promote HDR events, whereas among the nine compounds screened, the small molecule L755507 could enhance the HDR‐mediated targeted integration of reporter cassettes. Additionally, the L755507‐based approach allowed for the simultaneous integration of two different DNA fragments into the two targeted loci, that is, double knock‐in. Our established knock‐in system combining L755507, donor plasmids, and the CRISPR/Cas9 nickase system can reduce the workload for genetically modified strain generation, thus accelerating studies on the molecular mechanisms of biological phenomena.