bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge, attitude, and practice of house officers towards COVID-19
Authors: Alwerdani Mariam M , Said Emtenan A , Dosoky Wesam A , Sehsah Radwa , El-Gilany Abdel-Hady 
Published: June 2022

Objectives:
To assess the knowledge, attitude, and practice (KAP) towards COVID-19 and its associated factors among house officers.

Methods:
A multicentered crosssectional study on house officers was carried out using an online self-administered questionnaire. Sociodemographic data and data related to KAP towards COVID-19 were collected. Besides, KAP level of the house offices was recorded and factors associated with good KAP were determined.

Results:
This study included 555 house officers from 10 different hospitals with 128 males and 427 females. Almost half of the house officers had good knowledge and a favorable attitude (46.1% and 51%, respectively) on COVID-19. Still, 82.5% of them were committed to good practice of preventive measures. Besides, percentages of good knowledge and practice among those with chronic diseases or those who knew someone infected with SARS-CoV-2 were higher, but the differences were not statistically significant (P>0.05). In addition, the percentages of females with good practice were higher than those of males, with no statistical difference (P>0.05).

Conclusion:
House officers showed a good KAP towards COVID-19. Being aware of gaps in KAP can help to effectively contain the current pandemic.
Leukemoid reaction in a patient with COVID-19 infection
Authors: Agrawal Prabhat , Gautam Ashish , Pandey Anjana , Kumar Harendra , Pursnani Nikhil 
Published: June 2022

Rationale:
COVID-19 usually presents with flu-like symptoms and signs, but some rare presentations like leukemoid symptoms cannot be ignored.

Patient's concerns:
A 37-year-old female presented to the outpatient department with flu-like symptoms.

Diagnosis:
The RT-PCR test for SARS-CoV-2 infection was positive, while complete blood cell and peripheral blood smear showed leukemoid reaction.

Intervention:
Paracetamol and fexofenadine for flu-like symptoms and leukemoid presentation.

Outcomes:
On the 10th day, the patient was asymptomatic and RT-PCR was negative. So the patient was discharged and leukemoid presentation subsided after clearance of viral disease.

Lessons:
COVID-19 has a myriad of presentations, and unusual symptoms/signs especially in this pandemic could be induced by COVID-19 infection.
Dexmedetomidine as an Adjuvant to 0.25% Bupivacaine in Ultrasound Guided Femoral Nerve Block for Preoperative Positioning and Postoperative Analgesia in Patients Undergoing Elective Surgery for Fracture Shaft of Femur
Authors: Vinod M. , Malashree G , Goud E. Sundeep , Ravikumar K. 
Published: June 2022

Background:
Femur fracture causes excruciating pain and surgical repair is recommended. To obtain satisfactory patient co-operation in the perioperative period, various analgesics have been used. Femoral nerve block (FNB) provides an excellent alternative for analgesia in the perioperative period. Dexmedetomidine of up to 2 μg.kg−1 has been used in FNB as adjuvants in lower limb surgeries.

Aims:
The aim was to study the effect of addition of Dexmedetomidine to Bupivacaine in FNB on the comfort of positioning for subarachnoid block (SAB) and postoperative analgesia.

Materials and Methods:
Prospective, randomized, double-blind design was followed. Seventy American Society of Anesthesiologist I and II patients aged 18–70 years of either gender were randomly allocated into Group B (20 mL 0.25% Bupivacaine + 2 mL Normal Saline) and Group BD (received 20 mL 0.25% Bupivacaine + Dexmedetomidine 2 μg.kg−1 diluted to 2 mL) for FNB. Numerical rating scale (NRS) was recorded before and after FNB and comfort of positioning graded. After 10 min, subarachnoid block (SAB) was administered. NRS was recorded postoperatively until 24 h.

Results:
The comfort of positioning improved in both the groups after FNB but was statistically not significant when compared among the groups (P = 0.7). Duration of postoperative analgesia was significantly higher in the Group BD (741 min ± 97 min) compared to the Group B (440 min ± 45 min) (P = 0.001) and was statistically significant.

Conclusion:
FNB improved the comfort of positioning for SAB, but the addition of Dexmedetomidine did not have any added advantages with respect to comfort of positioning. However, the addition of Dexmedetomidine significantly increased the duration of postoperative analgesia with minimal hemodynamic changes.
Prevalence of Chronic Postsurgical Pain among Cancer Patients
Authors: Ramadan Mahmoud I. , Khudair Hussein Y. Abu , Obaid Abdullah T. , Yousef Ola A. , Sammour Raja A. 
Published: June 2022

Background:
Cancer patients accept surgeries as part of their treatment. They may not be aware of the possibility of surgical pain persisting long after the surgery. Understanding chronic postsurgical pain is essential for effective pain management.

Aims:
We aimed to assess the prevalence of chronic postsurgical pain in cancer patients and the associated symptom burden.

Settings and Design:
This study was carried out at a tertiary cancer center. It was a cross-sectional study.

Materials and Methods:
Participants who underwent surgeries were asked to provide feedback on the MD Anderson Symptom Inventory at 3 months.

Statistical Analysis Used:
Descriptive statistics were used. Statistical tests included Kruskal–Wallis test, Chi-square test, Fisher's exact test, and Spearman's correlation. Logistic regression was used to assess the influence of variables on the presence or absence of chronic postsurgical pain.

Results:
Nine hundred and eighteen participants completed the study. Ninety-two percent (n = 840) were asymptomatic. Eight percent (n = 78) had postsurgical pain. Chronic postsurgical pain was influenced by the type of surgery (P = 0.01), specifically orthopedic and thoracic surgeries. Patients who receive epidurals are three times less likely to continue to have pain at 3 months.

Conclusions:
The prevalence of chronic postsurgical pain at 3 months in this study is lower than the rates in the literature. It is still associated with symptom burden that interferes with daily life. The risk of developing chronic postsurgical pain increases with thoracic and orthopedic surgeries. The risk may be lowered with epidural analgesia.
Comparative assessment of morphological alterations in the dentin surface by sodium fluoride, 980 nm diode laser, and their combined application for use in the treatment of dentin hypersensitivity
Authors: Tanwar Shweta , Kumar Amit , Chetiwal Rajesh 
Published: June 2022

Context:
Lasers have been used as one of the most promising new modalities for dentin hypersensitivity. A synergistic action of lasers in association with desensitizing agents can favor the permanence of the desensitizer for a longer time than when they are used alone.

Aims:
The present study was aimed to evaluate the morphological characteristics of dentin surface by scanning electron microscopy after fluoride application and irradiation with 980 nm diode laser and their combined application.

Materials and Methods:
Sixty extracted human premolars were collected, prepared, and randomized into three groups. Group A involved tooth treated with sodium fluoride (NaF); Group B involved tooth irradiated by 980 nm GaAlAs (diode) laser; and Group C consisted of tooth sections irradiated by a diode laser with prior application of NaF. The morphological alterations were evaluated and compared using a scanning electron microscope.

Statistical Analysis:
The Kruskal–Wallis test was used for multiple group comparisons, and the post hoc Dunn's multiple comparison test was used for intergroup comparisons.

Results:
Group C, the fluoride-laser treated group, showed the lowest diameter of dentinal tubules (0.077 ± 0.021 μm) and had significantly the lowest number of open dentine tubules. Dunn's multiple comparison tests revealed that Group C had statistically significant tubule diameter reduction and had the lowest number of open tubules compared to both Group A and Group B (P < 0.0001 and P = 0.0007, respectively). In addition, Group C had significantly greater intertubular distance when compared to both Group A and Group B (P < 0.001).

Conclusion:
The 980 nm diode laser presents a promising new potential for treating dentin hypersensitivity, both alone and in conjunction with desensitizing agents. However, clinical trials are required to use it in regular clinical practice.
Patient-related factors associated with medication adherence behavior in patients with end-stage renal disease
Authors: Latif Anis A'lliya , Lee Kai Wei , Phang Kelly , Rashid Aneesa Abdul , Chan Nee Nee , Peh Suat Cheng , Thilaganathan Thiruventhiran , Ooi Pei Boon 
Published: June 2022

Objectives:
This systematic review aims to identify influencing factors of medication adherence behavior in patients with end-stage renal disease (ESRD), with a special interest in patient-related factors based on the World Health Organization adherence model.

Materials and Methods:
Primary electronic databases comprising PubMed, Scopus, Web of Science, Embase and Cochrane Library, as well as ProQuest (Health and Medical), ProQuest (Psychology), and EBSCOHost (APA PsychARTICLES) were used to search for literature on patient-related factors in medication adherence, from inception till August 31, 2021.

Results:
479 articles were identified and six articles meeting eligibility criteria were reviewed and remained in this systematic review. The present review found that despite different tools being used to measure ESRD's perception of medication's necessity and beliefs, there was a profound association between perception and beliefs with medication adherence behavior. There is a positive relationship between knowledge, belief, educational level, ethnicity, female, and medication adherence behavior. Mixed finding was reported between perception, age, and medication adherence behavior. However, there were no studies on patients' attitudes and medication adherence behavior as suggested in the WHO adherence model.

Conclusion:
Only a limited number of patient-related factors were available for evaluation in the current systematic review. Additional research is needed to advance the understanding of medication adherence behavior affected by patient-related factors on the medication and illness. However, the findings must be taken with caution because of the limited studies included in this review.
Clinical outcomes of benign brain tumors treated with single fraction LINAC-based stereotactic radiosurgery
Authors: Chew Chia-Hui , Chen Jin-Cherng , Hung Shih-Kai , Wu Tsung-Hsien , Lee Moon-Sing , Chiou Wen-Yen , Chen Liang-Cheng , Lin Hon-Yi 
Published: June 2022

Objectives:
Accelerator-based stereotactic radiosurgery (SRS) is a noninvasive and effective treatment modality widely used for benign brain tumors. This study aims to report 20-year treatment outcomes in our institute.

Materials and Methods:
From May 2001 to December 2020, 127 patients treated with LINAC-based single-fraction SRS for their benign brain lesions were included. A neurosurgeon and two radiation oncologists retrospectively reviewed all data. Computed tomography (CT) simulation was performed after head-frame fixation under local anesthesia. All planning CT images were co-registered and fused with gadolinium-enhanced magnetic resonance imaging taken within 3 months for lesions targeting and critical organs delineation. The marginal dose was prescribed at 60%–90% isodose lines, respectively, to cover ≥95% planning target volume. Outcome evaluations included clinical tumor control rate (TCR), defined as the need for salvage therapy, and radiological response, defined as no enlargement of >2 cm in the maximal diameter. Overall survival (OS) and adverse reaction (defined according to CTCAE 5.0) were also analyzed.

Results:
The present study included 76 female and 51 male patients for analysis. The median age was 59 years (range, 20–88 years). Their diagnoses were vestibular schwannoma (VS, n = 54), nonvestibular cranial nerve schwannoma (n = 6), meningioma (n = 50), and pituitary adenoma (n = 17). Totally 136 lesions were treated in a single fraction, predominantly skull base tumors, accounting for 69.1%. Median and mean follow-up duration was 49 and 61 months (range, 1–214 months), Overall TCR was 92.9%. The 5-year disease-specific TCR for VS, nonvestibular schwannoma, meningioma, and pituitary adenoma were 97.4%, 91.7%, 93.8%, and 83.3%. Salvage therapy was indicated for eight patients at 4–110 months after SRS. Among symptomatic patients, post-SRS symptom(s) was improved, stable, and worse in 68.2%, 24.3%, and 3.6%, respectively. Radiological response rate for 111 evaluable patients was 94.6% (shrinkage, 28.8%; stable, 65.8%). OS was 96.1% without treatment-related mortality. One patient with post-SRS cranial nerve injury (0.8%, involving the trigeminal nerve, grade 2 toxicities). No grade 3–4 acute or late toxicity was found.

Conclusion:
Our results suggested that LINAC-based SRS effectively controls tumor growth and tumor-related neurological symptoms for patients with benign brain tumors. SRS is less aggressive, associated with low neurological morbidity and no mortality. Continuous follow-up is indicated to conclude longer outcomes.
Performance analysis of SWIPT‐assisted adaptive NOMA/OMA system with hardware impairments and imperfect CSI
Authors: Guo Jing , Lu Jin , Wang Xianghui , Zhou Lili 
Published: June 2022

AbstractThis paper investigates the effect of hardware impairments (HIs) and imperfect channel state information (ICSI) on a SWIPT‐assisted adaptive nonorthogonal multiple access (NOMA)/orthogonal multiple access (OMA) system over independent and nonidentical Rayleigh fading channels. In the NOMA mode, the energy‐constrained near users act as a relay to improve the performance for the far users. The OMA transmission mode is adopted to avoid a complete outage when NOMA is infeasible. The best user selection scheme is considered to maximize the energy harvested and avoid error propagation. To characterize the performance of the proposed systems, closed‐form and asymptotic expressions of the outage probability for both near and far users are studied. Moreover, exact and approximate expressions of the ergodic rate for near and far users are investigated. Simulation results are provided to verify our theoretical analysis and confirm the superiority of the proposed NOMA/OMA scheme in comparison with the conventional NOMA and OMA protocol with/without HIs and ICSI.
Developing Molecular Surveillance Capacity for Asymptomatic and Drug-Resistant Malaria in a Resource-Limited Setting—Experiences and Lessons Learned
Authors: Han Kay Thwe , Han Zay Yar , Zainabadi Kayvan 
Published: June 2022

ABSTRACT.
The COVID-19 pandemic has highlighted the important role molecular surveillance plays in public health. Such capacity however is either weak or nonexistent in many low-income countries. This article outlines a 2-year effort to establish two high-throughput molecular surveillance laboratories in Myanmar for tracking asymptomatic and drug resistant Plasmodium falciparum malaria. The lessons learned from this endeavor may prove useful for others seeking to establish similar molecular surveillance capacity in other resource-limited settings.
Performance of SARS-CoV-2 Antigens in a Multiplex Bead Assay for Integrated Serological Surveillance of Neglected Tropical and Other Diseases
Authors: Gwyn Sarah , Abubakar Ado , Akinmulero Oluwaseun , Bergeron Eric , Blessing Ugboaja Nkechi , Chaitram Jasmine , Coughlin Melissa M. , Dawurung Ayuba B. , Dickson Felicia Nwatu , Esiekpe Mudiaga , Evbuomwan Erasogie , Greby Stacie M. , Iriemenam Nnaemeka C. , Kainulainen Markus H. , Naanpoen Thomas Andrew , Napoloen Loveth , Odoh Ifeanyichukwu , Okoye McPaul , Olaleye Temitope , Schuh Amy J. , Owen S. Michele , Samuel Awala , Martin Diana L. 
Published: June 2022

ABSTRACT.
Serosurveillance can provide estimates of population-level exposure to infectious pathogens and has been used extensively during the COVID-19 pandemic. Simultaneous, serological testing for multiple pathogens can be done using bead-based immunoassays to add value to disease-specific serosurveys. We conducted a validation of four SARS-CoV-2 antigens—full-length spike protein, two receptor binding domain proteins, and the nucleocapsid protein—on our existing multiplex bead assay (MBA) for enteric diseases, malaria, and vaccine preventable diseases. After determining the optimal conditions for coupling the antigens to microsphere beads, the sensitivity and specificity of the assay were determined on two instruments (Luminex-200 and MAGPIX) when testing singly (monoplex) versus combined (multiplex). Sensitivity was assessed using plasma from 87 real-time reverse transcription polymerase chain reaction (rRT-PCR) positive persons collected in March–May of 2020 and ranged from 94.3% to 96.6% for the different testing conditions. Specificity was assessed using 98 plasma specimens collected prior to December 2019 and plasma from 19 rRT-PCR negative persons and ranged from 97.4% to 100%. The positive percent agreement was 93.8% to 97.9% using 48 specimens collected > 21 days post-symptom onset, while the negative percent agreement was ≥ 99% for all antigens. Test performance was similar using monoplex or multiplex testing. Integrating SARS-CoV-2 serology with other diseases of public health interest could add significant value to public health programs that have suffered severe programmatic setbacks during the COVID-19 pandemic.
Kinetics, equilibrium and thermodynamics investigation on the adsorption of cr (vi) ions from wastewater using activated kigelia africana rind nano carbon
Authors: T Vimalarani  , Venkatraman B.R  
Published: June 2022

The goal of this research is to investigate the feasibility of using activated Kigelia africana rind nano carbon (KANC) to adsorb Cr (VI) ions from aqueous solutions through batch experiments. Effect of contact time, initial Cr(VI) ion concentration, activated KANC dose, initial solution pH, other ions and temperature on the Cr (VI) ions adsorption were examined. The sorption process was examined by applying Elovich, pseudo-second order and intraparticle diffusion rate. The best pH for Cr (VI) ions removal is in the range of 2.0-7.0 with more than 80-85% of Cr (VI) ions removed. The equilibrium time was found to be 45min and the adsorption data followed the pseudo-second-order kinetics. Isotherm data followed Langmuir isotherm model. The adsorption was endothermic and spontaneous in nature.
Analisis Penerapan PPN dan PPH Pasal 22 Atas Pengadaan Barang di Balai Jembatan Kementrian PUPR
Authors: Damarwati Intan , Gunardi Gunardi 
Published: June 2022

Tax is one of the main components of the Indonesian economy which serves as the source of the funding for APBD and APBN.The government treasurer as the functional official has the obligation and authority to deposit and report Value Added Tax (VAT) and Income TaxArticle 22 from every payment for the procurement of goods whose funding source is from the APBN. The purpose of this research is to find out the implementation of calculation, depositing, and reporting of VAT and Income Tax Article 22 for the procurement of goods at Balai Jembatan of the Ministry of Public Works and Public Housing.This study was conducted with the descriptive qualitative method fromDecember2021 to January 2022.The results of the research show that the VAT is calculated using a 10% rate, while the Income Tax Article 22 used a 1,5% rate, which is then deposited using the Persepsi payment code from Kantor Pos Indonesia. Reportings are done by using SPT Masa Unifikasi which needs to be done in 20 days maximum from the end of the tax period.Reporting, depositing, and calculation of VAT and Income Tax Article 22 by the treasurer of Balai Jembatanof the Ministry of Public Works and Public Housing have been carried out in accordance with the regulations regarding tax from the Ministry of Finance. However, there are still delays in reporting VAT and Income Tax Article 22 in several tax periods.
Keywords: Government Treasurer, VAT, Income Tax Article 22
Efektivitas Pelaksanaan Penagihan Pajak Aktif Dalam Pencairan Tunggakan Pajak
Authors: Nissa Choirun , Muslimin Muslimin 
Published: June 2022

This study aims to test and analyze the effectiveness of the implementation of active tax collection in tax arrears. The object of this research is the billing performance. And the informants in this research are Mr. Mudiantoro and Mr. Wildan Wijaya who are related to the KPP Pratama Surabaya Mulyorejo. The subject of this research is the tax revenue report, as well as other data for 2018-2020. The research uses an interactive model, whose elements include data reduction (data reduction), data display (data display), and drawing/verifying conclusions. The type of data used in this research is qualitative. The results of this study indicate that the state of active tax collection with letters as billing actions issued is still experiencing ups and downs so that it can be said that taxpayers are not fully aware of their tax obligations, tax collection reports with warning letters in 2018-2020 are still classified as ineffective, Tax collection reports with forced letters in 2018-2020 are still classified as ineffective.
Keywords: active tax collection, taxpayer, tax collection report
Analisis Sistem Pengendalian Intern Atas Pembayaran Gaji dan Upah pada Pt. Perkebunan Nusantara XII
Authors: Qonita Amira , Muslimin Muslimin 
Published: June 2022

This study aims to determine the analysis of the internal control system for the payment of salaries and wages. The type of research conducted is descriptive method, this research uses qualitative. Sources of primary data in this study in the form of interviews from the parties concerned at PT. Nusantara XII Plantation Surabaya. The results showed that PT. Perkebunan Nusantara XII did not experience problems with the salary and wage payment system. This is evidenced by the division of tasks for each section and also a healthy practice. The implementation of the internal control system for payment of salaries and wages has been going very well, where in its application there are incentives for company policies to achieve goals and all employees are required to comply and there are sanctions for employees who do not comply.
Keywords: analysis of internal control systems, payment of salaries and wages
Analisis Penggunaan Aplikasi Kasir ‘’Qasir’’ Dalam Sistem Informasi Penerimaan Kas di Kala Kopi
Authors: Budiharto Kartika , Andayani Sari 
Published: June 2022

This study aims to analyze the use of the cashier application ''QASIR'' in the cash receipts information system at Kala Kopi. The object of this research is the use of cashier applications in cash receipts at Kala Kopi. The subjects in this study were employees, owners of Kala Kopi and consumers of Kala Kopi. This research is quantitative descriptive. This study uses primary data used in this study, namely the source comes from the finance department through observations, interviews and documentation conducted to employees or owners of Kala Kopi and Kala Kopi consumers who pay by cash or digital wallets (e-wallet). The secondary data used in this study are documents or records in cash receipts and presentations when using the cashier application at Kala Kopi. The results of this study were the cash receipt system at Kala Kopi was run with the help of the Qasir cashier application system. the results of the research that has been carried out, in recording cash receipts, cash and non-cash payments (e-wallet) are equally efficient as long as they are still using the "Qasir" cashier application. the results of research that have been carried out and interviews by cashier application users and Kala Kopi consumers, the recording of cash receipts recorded at Kala Kopi and those received by Kala Kopi consumers is in accordance with
Keywords: Digital wallet, cash receipts information system, qasir application