bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuromorphic devices based on fluorite‐structured ferroelectrics
Authors: Lee Dong Hyun , Park Geun Hyeong , Kim Se Hyun , Park Ju Yong , Yang Kun , Slesazeck Stefan , Mikolajick Thomas , Park Min Hyuk 
Published: October 2022

AbstractA continuous exponential rise has been observed in the storage and processing of the data that may not curtail in the foreseeable future. The required data processing speed and power consumption are restricted by the buses between the logic and memory devices that are characteristic of the von Neumann computing architecture. Bio‐mimicking neuromorphic computing has garnered considerable academic and industrial interest to resolve these challenges. Additionally, devices based on emerging nonvolatile memories capable of mimicking the behaviors of synapses and neurons, which are the main elements in biological computing systems (brains), are attracting significant interest from the device community. With the discovery of ferroelectricity in fluorite‐structured oxides, such as HfO2and ZrO2, which are compatible with the state‐of‐the‐art complementary‐metal‐oxide‐semiconductor processes, ferroelectric devices have rapidly evolved as the main direction of these research and development activities. Fundamental science related to fluorite‐structured ferroelectrics has been intensively studied over the last decade. At present, the focus is gradually moving to practical applications, including neuromorphic computing and advanced classical processing or memory units in the conventional von Neumann architecture. However, despite its rapid development, the wealth of recent progress in neuromorphic computing devices based on fluorite‐structured ferroelectrics has not been reviewed and systemized. This progress report comprehensively reviews and systemizes the recent progress in artificial synaptic and spiking neuron devices for neuromorphic computing based on fluorite‐structured ferroelectrics.image
Proanthocyanidins suppress NLRP3 inflammasome and M1 macrophage polarization to alleviate severe acute pancreatitis in mice
Authors: Sheng Li‐Ping , Han Chao‐Qun , Ling Xin , Guo Xian‐Wen , Lin Rong , Ding Zhen 
Published: October 2022

AbstractThe role of reactive oxygen species (ROS) is crucial for the pathogenesis of acute pancreatitis (AP). Proanthocyanidins (PAs) have been confirmed to exert antioxidant activity. Our study aimed to determine whether PAs alleviated SAP via reducing ROS, suppressing NLRP3 inflammasome, and inhibiting M1 macrophage polarization. Our study investigated the protective effects of PAs on pancreatic histopathological injury using SAP mice. The effects of PAs on macrophages were investigated in inflammatory RAW 264.7 cells or mouse bone marrow‐derived macrophages (BMDMs) induced by lipopolysaccharide (LPS). Immunofluorescence staining and/or western blot assay were employed to evaluate NLRP3 inflammasome in macrophages and pancreatic tissue. Cell counting kit‐8 (CCK‐8) was used to access effects of PAs on cell viability and cytometry flow was used to determine the effects of the PAs on the ROS levels of the RAW 264.7 cells. Then, we evaluated M1 macrophage polarization using flow cytometry or real‐time quantitative polymerase chain reaction (RT‐qPCR). PAs administration alleviated pancreatic inflammation in SAP mice. The PAs depressed NLRP3 inflammasome and inhibited M1 macrophage polarization in pancreatic tissue. We also found that the PAs showed no cellular toxicity but decreased ROS levels in RAW 264.7 cells, downregulated the NLRP3 inflammasome in the macrophages, and inhibited cell M1 macrophage polarization. Our study indicates the anti‐inflammatory properties of the PAs on SAP mice by decreasing ROS levels, suppressing NLRP3 inflammasome, and M1 macrophage polarization.
Rapid production method with increased yield of high‐purity extracellular vesicles obtained using extended mitochondrial targeting domain peptide
Authors: Lim Kyung Min , Han Ji‐Hye , Lee Yoonjoo , Park Junghee , Dayem Ahmed Abdal , Myung Seung‐Hyun , An Jongyub , Song Kwonwoo , Kang Geun‐Ho , Kim Sejong , Kwon Sangwoo , Kim Kyung Sook , Cho Ssang‐Goo , Kim Tae‐Hyoung 
Published: October 2022

AbstractExtracellular vesicles (EVs) are nano‐sized membranous structures involved in intercellular communication and various physiological and pathological processes. Here, we present a novel method for rapid (within 15 min), large‐scale production of high‐purity EVs using eMTDΔ4, a peptide derived from Noxa. The treatment of mesenchymal stem cells derived from human Wharton's jelly after trypsinization and subsequent eMTDΔ4 stimulation in a chemically defined sucrose buffer with orbital shaking led to a substantial increase (approximately 30‐fold) in EV production with markedly high purity (approximately 45‐fold). These EVs (TS‐eEVs) showed higher regenerative and immunomodulatory potential than natural EVs obtained from the culture media after 48 h. The calcium chelator BAPTA‐AM and calpain inhibitor ALLM, but not the natural EV biogenesis inhibitor GW4869, blocked the TS‐eEV production induced by eMTDΔ4, indicating that the eMTDΔ4‐mediated regulation of intracellular calcium levels and calpain activity are closely associated with the rapid, mass production of TS‐eEVs. The present study may lead to considerable advances in EV‐based drug development and production of stem cell‐derived EVs for cell therapy.
Modified activated carbon derived from chestnut oak shells as a new sorbent for the needle‐trap extraction
Authors: Roostaie Ali , Mohammadiazar Sirwan , Haddad Reza , Ebrahimi Bahram 
Published: October 2022

In this study, an acid‐treated‐activated carbon was prepared from chestnut oak shell carbonization followed by modification with hydrochloric acid/nitric acid and then used as a new sorbent for headspace needle‐trap extraction of chlorophenol compounds from aqueous solutions. Different techniques, including scanning electron microscopy, nitrogen adsorption‐desorption analysis, and Fourier transform‐infrared spectroscopy were used for the characterization of the sorbents. The effects of some experimental parameters, including the temperature, pH, sorbent amount, and time of extraction were optimized. The developed method is fast and sensitive, providing low and sub ng/L detection limits. The limits of detection and quantification were in the range of 0.75–5 and 5–15 ng/ml, respectively, and the equilibrium time was 20 min. Wide linearity in the range of 15–2000 ng/L with R2 > 0.9993 was obtained. Repeatability of the method was accessed at 50, 100, and 200 ng/L concentration levels and RSD% of 5%–12% was achieved. The introduced method was applied for analyzing real water samples containing spiked chlorophenols, and the relative recovery values were found to be in the range of 84%–99% at the concentration levels of 50, 100 and 200 ng/L.
Posttraumatic stress disorder and functional impairment among World Trade Center Health Registry enrollees 14–15 years after the September 11, 2001, terrorist attacks
Authors: Trivedi Niti U. , Gargano Lisa M. , Brackbill Robert M. , Jacobson Melanie H. 
Published: October 2022

AbstractThe September 11, 2001, terrorist attacks on the World Trade Center (WTC) in New York City (9/11) had health‐related consequences, including posttraumatic stress disorder (PTSD). PTSD is associated with functional impairment, which varies by symptom severity and other factors. This study aimed to identify predictors of functional impairment in individuals with low versus high PTSD symptom severity levels. WTC Health Registry enrollees exposed to 9/11 were surveyed four times between 2003 and 2015; cumulated data for individuals who endorsed at least one symptom on the PTSD Checklist–Civilian Version (PCL‐C) at Wave 4 (2015–2016) were included (N = 30,287) and examined cross‐sectionally. Individuals were classified based on PCL‐C scores as having low/no (2–29) or high levels of PTSD symptom severity (≥ 44). Functional impairment was defined as subsequent difficulties in daily living. Among low/no PTSD severity participants, adjusted odds ratios (aORs) for the associations between functional impairment and poor self‐rated health (vs. good), low social support (vs. high), and no physical activity (vs. active) were 1.23–1.92. In the same group, low versus high household income was associated with more functional impairment, aOR = 1.34, 95% CI [1.13, 1.59]. Among participants with high‐level PTSD symptoms, women, aOR = 1.70, 95% CI [1.31, 2.20], and Hispanic enrollees, aOR = 1.76, 95% CI [1.31, 2.36], were more likely to report an absence of impairment. Self‐rated health, social support, and physical activity emerged as important predictors of PTSD‐related functional impairment across PTSD symptom severity levels, supporting clinical interventions targeting these factors.
Surfactant Assisted In Situ Synthesis of Nanofibrillated Cellulose/Polymethylsilsesquioxane Aerogel for Tuning Its Thermal Performance
Authors: Gupta Pragya , Sathwane Manoj , Chhajed Monika , Verma Chhavi , Grohens Yves , Seantier Bastien , Agrawal Ashish K. , Maji Pradip K. 
Published: October 2022

AbstractNanofibrillated cellulose (NFC) and polymethylsilsesquioxane (PMSQ) based aerogel are prepared by the sol‐gel method. The objective of this work is to study the impact of surfactant and base catalyst on the thermal and mechanical performance of the corresponding aerogel. The rheological premonitory assists in predicting the bulk properties of the aerogel. The chemical structure of the aerogel is studied by Fourier‐transform infrared spectroscopy (FTIR), X‐ray diffraction (XRD), X‐ray photoelectron spectroscopy (XPS), and solid‐state nuclear magnetic resonance (NMR). X‐ray microtomographic (XMT) analysis confirms the homogeneous and monolithic structure of the aerogel. The lowest thermal conductivity is achieved as 23.21 mW m−1 K−1 with V‐0 and HBF rating through UL‐94 test. Thermal performance of aerogels is cross‐verified through modeling and simulation in COMSOL multiphysics platform. The mechanical properties of aerogel are evaluated by monolithic compression test in axial and radial compression test up to 90% strain, cyclic compression loading–unloading, and reloading test, flexural test, and dynamic mechanical analysis. The time‐temperature analysis has shown around 5 °C temperature difference in the middle of the room after using the aerogel panel at the exposed surface, which assists in the practical application of the synthesized aerogel panel.
The effects of time‐restricted eating and weight loss on bone metabolism and health: a 6‐month randomized controlled trial
Authors: Papageorgiou Maria , Biver Emmanuel , Mareschal Julie , Phillips Nicholas Edward , Hemmer Alexandra , Biolley Emma , Schwab Nathalie , Manoogian Emily N. C. , Gonzalez Rodriguez Elena , Aeberli Daniel , Hans Didier , Pot Caroline , Panda Satchidananda , Rodondi Nicolas , Ferrari Serge L. , Collet Tinh‐Hai 
Published: October 2022

AbstractObjectiveThis study explored the impact of time‐restricted eating (TRE) versus standard dietary advice (SDA) on bone health.MethodsAdults with ≥1 component of metabolic syndrome were randomized to TRE (ad libitum eating within 12 hours) or SDA (food pyramid brochure). Bone turnover markers and bone mineral content/density by dual energy x‐ray absorptiometry were assessed at baseline and 6‐month follow‐up. Statistical analyses were performed in the total population and by weight loss response.ResultsIn the total population (n = 42, 76% women, median age 47 years [IQR: 31‐52]), there were no between‐group differences (TRE vs. SDA) in any bone parameter. Among weight loss responders (≥0.6 kg weight loss), the bone resorption marker β‐carboxyterminal telopeptide of type I collagen tended to decrease after TRE but increase after SDA (between‐group differences p = 0.041), whereas changes in the bone formation marker procollagen type I N‐propeptide did not differ between groups. Total body bone mineral content decreased after SDA (p = 0.028) but remained unchanged after TRE (p = 0.31) in weight loss responders (between‐group differences p = 0.028). Among nonresponders (<0.6 kg weight loss), there were no between‐group differences in bone outcomes.ConclusionsTRE had no detrimental impact on bone health, whereas, when weight loss occurred, it was associated with some bone‐sparing effects compared with SDA.
Mechanical and thermal performances of styrene butadiene rubber nanocomposites with boron nitride nanosheets, carbon nanotubes, and the hybrid filler system
Authors: Gu Lichao , Nan Hao , Xing Ruiguang , Pan Gaofei , Wang Yufei , Ge Xin 
Published: October 2022

AbstractPreparation of rubber nanocomposites using two or more nanofillers with different geometries is a new and promising approach. In this work, the effects of boron nitride nanosheets (BNNS), carbon nanotubes (CNT) and their hybrid (BNNS‐CNT) on the performances of styrene butadiene rubber (SBR) nanocomposites are systematically studied. The mechanical properties of the nanocomposites are significantly enhanced by the nanofillers. The tensile strength of unfilled SBR is only 1.30 ± 0.18 MPa, which increases to 1.72 ± 0.24 MPa (BNNS), 4.09 ± 0.35 MPa (CNT), and 3.37 ± 0.29 MPa (BNNS‐CNT) at 4 phr, respectively. Similarly, the tear strength of unfilled SBR is 8.0 kN/m, which increases to 13.8 kN/m (BNNS), 16.1 kN/m (CNT) and 18.2 kN/m (BNNS‐CNT) at 4 phr, respectively. Moreover, the thermal behavior of the nanocomposites are analyzed. Compared with single nanofiller BNNS or CNT, BNNS‐CNT hybrid nanofiller not only effectively improves the mechanical properties of nanocomposites, but also imparts better thermal properties. It is proved that the thermal decomposition temperature of SBR/4phr BNNS‐CNT is increased by nearly 7°C compared with unfilled SBR.
Sustainable nanocomposite coating for moulded pulp with enhanced barrier properties for food packaging applications
Authors: Klayya Supattra , Tawichai Nattaya , Intatha Uraiwan , Zhang Han , Bilotti Emiliano , Soykeabkaew Nattakan 
Published: October 2022

AbstractDue to poor barrier properties and high sensitivity to moisture, the applications of paper‐based food packaging remain limited. While gaining high barrier performance and surface durability, laminating papers with binders and other materials often leads to reduced recyclability and sustainability. Herein, we present a promising approach to improve the barrier properties and surface oil resistance of bagasse moulded pulp while preserving its green profile. A bio‐nanocomposite layer, combining nanocellulose and shellac (natural polyester), was coated on the surface of moulded pulp. This nanocomposite coating layer provides excellent gas barrier and water barrier performance simultaneously, thanks to the ester modification of nanocellulose to improve its hydrophobicity. With a good compatibility and dispersion in the shellac matrix phase, the modified nanofibrillated cellulose demonstrated an improved barrier performance compared with the unmodified nanofibrillated cellulose. Oxygen transmission rate and water vapour transmission rate of the coated pulps were in the range 60–300 cm3 m−2 day−1 and 10–30 g m−2 day−1, respectively, comparable to those of conventional food packaging materials. The surface resistance of the coated pulps was also greatly improved, indicated by the water contact angle, oil contact angle, Kit test and oil resistance test in a bowl model. The nanocomposite was able to enhance the tensile strength of the moulded pulp by 23%. In summary, the current sustainable nanocomposite coating layer demonstrated great potential in converting paper‐based materials to high barrier and sustainable food packaging. © 2022 Society of Industrial Chemistry.
Flow‐field‐assisted shaping of linear low‐density polyethylene/low‐entanglement ultra‐high molecular weight polyethylene blends with enhanced mechanical properties and thermal conductivity
Authors: Zhang Yu , Yan Xiang , Ye Chunlin , Tao Gan , Zhang Letian , Xing Jinheng , Li Wei , Wang Jingdai , Yang Yongrong 
Published: October 2022

AbstractLinear low‐density polyethylene (LLDPE) is reinforced with low‐entanglement ultra‐high molecular weight polyethylene (UHMWPE) and formed using different melt processing methods. The results show that the low‐entanglement UHMWPE has good compatibility with LLDPE within a low addition range, which significantly improves the crystallinity and long period of LLDPE/UHMWPE composites. Furthermore, the shish‐kebab structure of the composite material is more perfect after injection molding and hot drawing. Due to the optimized structure, the mechanical properties of the composite are greatly improved. After hot drawing, the Young's modulus and tensile strength of the composites are increased by 350% and 565% respectively. Simultaneously, after injection molding and hot stretching molding, the thermal conductivity of the material is increased by 138% and 711% respectively. The thermal conductivity of the materials can be significantly improved by hot drawing. The current study opens a new avenue for the preparation of bulk polymers using the LLDPE matrix with simultaneously enhanced thermal conductivity and mechanical properties, with great potential for applications in thermal management. © 2022 Society of Industrial Chemistry.
Synthesis, characterization and computational studies for (2′S*,3R*,3′S*,8a′R*)‐2′,3′‐bis(ethoxycarbonyl)‐2‐oxo‐2′,3′‐dihydro‐8a′H‐spiro[indoline‐3,1′‐indolizine]‐6′‐carboxylic acid and some derivatives
Authors: Almutaleb Arabya A. A. , Alabbasi Aisha A. 
Published: October 2022

AbstractIn this article, we present advances related to 1,3‐dipolar cycloadditions of generated pyridinium ylides and apply these results to specific 1,3‐dipolar cycloaddition reactions with oxindole dipolarophiles. The ylide discussed in this article is generated from alkylation reactions between substituted pyridines and a primary electrophile. Cycloaddition reactions proceeding from pyridinium ylides and various oxindoles are reported with good stereo‐ and regioselectivity. Cycloaddition reactions take place by the overlap of the HOMO of the dipole and the LUMO of the dipolarophile when the two orbitals have similar energies, resulting in the formation of two new bonds. To get more insight into the reaction nature, a quantum chemical simulation was performed. A computational study is performed on the reactants (pyridinium ylides and oxindoles) and resulting cycloadducts. The present analysis reveals that the cycloaddition reactions under study can be classified in the normal electron demand category. Regioselectivity and mechanism of 1,3‐cycloaddition reactions are studied in the light of several theoretical approaches such as activation energy, Houk's rule based on the FMO theory, and the DFT reactivity indices.
Azaboracyclooctatetraenes reveal that the different aspects of triplet state Baird‐aromaticity are nothing but different
Authors: Preethalayam Preethanuj , Proos Vedin Nathalie , Radenković Slavko , Ottosson Henrik 
Published: October 2022

AbstractThe Baird‐aromaticity of BN/CC cyclooctatetraene isosteres (azaboracyclooctatetraenes) in their lowest triplet states (T1) has been explored through computations of various aromaticity indices that describe the different aspects of aromaticity (magnetic, electronic, energetic and geometric). While cyclooctatetraene (COT) is aromatic in its T1 state following Baird's 4n rule, we now reveal that the degrees of Baird‐aromaticity of its BN/CC isosteres vary with aromaticity aspect considered. The thermodynamically most stable octagonal B4N4H8 isomer, having an alternating B and N pattern (borazocine, B4N4COT‐A), is only weakly aromatic or nonaromatic in T1 according to energetic and electronic indices, while magnetic descriptors suggest it to have about two thirds the Baird‐aromaticity of T1 state COT (3COT). The extent of Baird‐aromaticity of intermediate BN/CC isosteres also varies markedly with aromaticity aspect considered. The strong aromaticity of 3B4N4COT‐A according to magnetic descriptors can be linked to the symmetries of the orbitals involved in the virtual transitions from occupied to unoccupied orbitals, which describe the response of a molecule in an external magnetic field. However, the magnetic aspect of T1 state Baird‐aromaticity (response aromaticity) is not related to the electronic and energetic aspects (intrinsic aromaticity), findings that underline earlier observations on differences between the various aspects of the aromaticity phenomenon (or phenomena).
High reactivity and bactericidal effects of plasma‐activated mist from hydrogen peroxide solution
Authors: Zhou Yangyang , Jiang Tao , Zhang Li , Wang Sen , Zhou Renwu , Cui Xinglei , Fang Zhi 
Published: October 2022

AbstractHydrogen peroxide solutions are often utilized in logistics sterilization by misting, although their sterilizing capacity is diminished. To meet the high‐efficient and long‐term sterilization requirements of logistics, the reactivity and bactericidal efficiency are improved with plasma‐activated H2O2 solutions mist (PAHM). PAHM promotes an approximately double increase in the concentration of reactive nitrogen species, four times increase in the O3 concentration, and 36.2 times increase in H2O2 compared with water mist activation. Escherichia coli and Staphylococcus aureus are selected as the model microorganisms to evaluate the bactericidal activity. Results show that PAHM can reduce the numbers of both bacteria by two orders of magnitude after 3 min of treatment, similar to inactivated H2O2 for 10 min of treatment.
Theoretical Applications in Children and Youth Information Behavior Research: 1999–2019
Authors: Bilal Dania 
Published: October 2022

ABSTRACTChildren and youth information behavior (CYIB) research has grown substantially in the past two decades. However, this research lacks systematic analysis of the scholarly journal literature, especially with respect to theoretical applications. This study content‐analyzed articles published in fourteen key scholarly journals covering 1999 to 2019. The findings revealed that of the 893 articles retrieved from five online databases, 22.6% were relevant to theory use. Of these, 116 articles (60%) were theoretically grounded in theories or models. There was considerable growth in the use of theories as frameworks for the 2010–2019 period, as compared to the 1999–2009 period. Five key journals contributed the highest number of articles with theories or models applied as frameworks. Authors used more models than theories to ground their work. There was a frequent mention of theories or models in various sections of the articles, especially the introduction and review of the literature. The findings make a unique contribution to our understanding of the nature of theory use in CYIB research, its applications, and evolution over time, as well as strengths, weaknesses, and trends. This study has implications for LIS education, research, and practice. It also has theoretical and methodological implications.
Scholars Experiencing Epistemic Injustice Due to Management of Scholarly Outputs
Authors: Ford Angela , Alemneh Daniel 
Published: October 2022

AbstractScholars from regions outside of high‐income countries experience additional barriers as active consumers, producers, and sharers of scholarly outputs. This study will examine these barriers through a lens based on critical theories, specifically those focused on epistemic injustice. The findings will highlight the experienced impediments and demonstrate theoretically how disparities can be categorized. The findings will also highlight current publishing paradigms affecting the management of scholarly outputs and at times perpetuating these injustices. Possible future research to support these claims will also be discussed.