bluuebunny/crossref_metadata_2025_split huggingface dataset:
An ambient assisted living architecture for hospital at home coupled with a process-oriented perspective
Authors: Sulis Emilio , Amantea Ilaria Angela , Aldinucci Marco , Boella Guido , Marinello Renata , Grosso Marco , Platter Paolo , Ambrosini Serena 
Published: September 2022

AbstractThe growing number of next-generation applications offers a relevant opportunity for healthcare services, generating an urgent need for architectures for systems integration. Moreover, the huge amount of stored information related to events can be explored by adopting a process-oriented perspective. This paper discusses an Ambient Assisted Living healthcare architecture to manage hospital home-care services. The proposed solution relies on adopting an event manager to integrate sources ranging from personal devices to web-based applications. Data are processed on a federated cloud platform offering computing infrastructure and storage resources to improve scientific research. In a second step, a business process analysis of telehealth and telemedicine applications is considered. An initial study explored the business process flow to capture the main sequences of tasks, activities, events. This step paves the way for the integration of process mining techniques to compliance monitoring in an AAL architecture framework.
Anamorphic chaetosphaeriaceous fungi from China
Authors: Wu Wenping , Diao Yongzhao 
Published: September 2022

AbstractChaetosphaeriaceae is one of the largest families in Sordariomycetes with its members commonly found on decaying leaf, fruit, branch, bark and wood in both terrestrial and submerged environment in nature. This paper reports our research result of diversity, taxonomy and phylogeny of anamorphic Chaetosphaeriaceae in China, which is based on a systematic study with an integrated approach of morphological observation and phylogenetic analysis for a large collection (> 1300 herbarium specimens and 1100 living strains). The family Chaetosphaeriaceae is expanded to accommodate 89 accepted genera, including 22 new genera and 10 newly assigned genera. Most of these genera (except forChaetosphaeriaand several other relatively large genera) are delimitated as monophyletic genera with well-defined diagnostic characters in morphology. The phylogenetic connection of non-phialidicSporidesmium-like fungi is further confirmed and expanded to 10 different genera. The polyphyleticCodinaea/Dictyochaeta/Tainosphaeriacomplex is further resolved with a taxonomic framework of 28 monophyletic genera by redelimitation ofCodinaeaandDictyochaetawith narrower concept, acceptance of the 16 established genera, and finally introduction of 10 new genera.Chloridiumis phylogenetically redefined as monophyletic genus with narrower concept as typified by the type species, but a systematic review in both generic and species level is still needed. For biodiversity of chaetosphaeriaceous fungi, a total of 369 species in 76 genera, including 119 new species, 47 new combinations, and one new name, are documented. The identification keys are provided for most genera, especially the large genera such asCodinaeas. str.,Codinaeella,Stilbochaeta,Cryptophiale,Thozetella,DinemasporiumandPseudolachnella. In addition, ten known species were excluded from the family and reclassified. Systematic revision of several relatively large polyphyletic genera should be conducted in future studies, includingBahusutrabeeja,Ellisembia,Stanjehughesia,Cacumisporium,Chaetosphaeria,Chloridium,Craspedodidymum,Cryptophiale,Cryptophialoidea,Dictyochaetopsis,Minimidochium, and many published species ofCodinaeaandDictyochaeta.
A review of formulations and preclinical studies of inhaled rifampicin for its clinical translation
Authors: Khadka Prakash , Dummer Jack , Hill Philip C. , Katare Rajesh , Das Shyamal C. 
Published: September 2022

AbstractInhaled drug delivery is a promising approach to achieving high lung drug concentrations to facilitate efficient treatment of tuberculosis (TB) and to reduce the overall duration of treatment. Rifampicin is a good candidate for delivery via the pulmonary route. There have been no clinical studies yet at relevant inhaled doses despite the numerous studies investigating its formulation and preclinical properties for pulmonary delivery. This review discusses the clinical implications of pulmonary drug delivery in TB treatment, the drug delivery systems reported for pulmonary delivery of rifampicin, animal models, and the animal studies on inhaled rifampicin formulations, and the research gaps hindering the transition from preclinical development to clinical investigation. A review of reports in the literature suggested there have been minimal attempts to test inhaled formulations of rifampicin in laboratory animals at relevant high doses and there is a lack of appropriate studies in animal models. Published studies have reported testing only low doses (≤ 20 mg/kg) of rifampicin, and none of the studies has investigated the safety of inhaled rifampicin after repeated administration. Preclinical evaluations of inhaled anti-TB drugs, such as rifampicin, should include high-dose formulations in preclinical models, determined based on allometric conversions, for relevant high-dose anti-TB therapy in humans.Graphical abstract
The Brachypterous Species of Passalus (Pertinax) (Coleoptera: Passalidae), with the Description of a New Species from Sierra Nevada de Santa Marta, Colombia
Authors: Jiménez-Ferbans Larry , Reyes-Castillo Pedro , Bevilaqua Marcus 
Published: September 2022

AbstractBrachypterism is a common condition cited in passalid beetles, mainly associated to species with strictly montane distributions. In the New World Passalids, brachypterism has been reported especially in the tribe Proculini, for which almost all genera have brachypterous species; meanwhile, in Passalini, the other Netropical tribe, it has been cited only for the genusPassalus, mainly in the subgenusPassalus(Passalus). Here we present a commented list of the brachypterous species of the subgenusPassalus(Pertinax); we redescribedPassalus gravelyiMoreira,P.quitensis(Kaup),P.striatissimusLuederwaldt, andP. sulcifrons(Kuwert) and describe a new species from Sierra Nevada de Santa Marta, Colombia.
Hybridizing slime mould algorithm with simulated annealing algorithm: a hybridized statistical approach for numerical and engineering design problems
Authors: Ch Leela Kumari , Kamboj Vikram Kumar , Bath S. K. 
Published: September 2022

AbstractThe existing slime mould algorithm clones the uniqueness of the phase of oscillation of slime mould conduct and exhibits slow convergence in local search space due to poor exploitation phase. This research work exhibits to discover the best solution for objective function by commingling slime mould algorithm and simulated annealing algorithm for better variation of parameters and named as hybridized slime mould algorithm–simulated annealing algorithm. The simulated annealing algorithm improves and accelerates the effectiveness of slime mould technique as well as assists to take off from the local optimum. To corroborate the worth and usefulness of the introduced strategy, nonconvex, nonlinear, and typical engineering design difficulties were analyzed for standard benchmarks and interdisciplinary engineering design concerns. The proposed technique version is used to evaluate six, five, five unimodal, multimodal and fixed-dimension benchmark functions, respectively, also including 11 kinds of interdisciplinary engineering design difficulties. The technique’s outcomes were compared to the results of other on-hand optimization methods, and the experimental results show that the suggested approach outperforms the other optimization techniques.
The longitudinal association between coffee and tea consumption and the risk of metabolic syndrome and its component conditions in an older adult population
Authors: Wong Tommy Hon Ting , Burlutsky George , Gopinath Bamini , Flood Victoria M. , Mitchell Paul , Louie Jimmy Chun Yu 
Published: September 2022

Abstract
The present study aimed to assess the longitudinal associations of coffee and tea consumption with metabolic syndrome and its component conditions in a group of Australian older adults who participated in the Blue Mountains Eye Study (n 2554, mean age: 64 years, 43 % female). Participants’ coffee and tea intake were measured using a validated food frequency questionnaire. Hazard ratios (HRs) over a 10-year period were estimated using Cox hazard regression models adjusting for lifestyle factors. Results showed that coffee consumption was not associated with the incidence of metabolic syndrome, high fasting glucose, high triglycerides, central obesity, high blood pressure and low HDL-cholesterol (HDL-C). Tea consumption was not associated with incidence of metabolic syndrome and the component conditions except for the risk of having low HDL-C, in which a nominally inverse association was observed (multivariate-adjusted HR at 2–3 cups/d: 0⋅48, 95 % CI 0⋅26, 0⋅87, P = 0⋅016; 4 cups/d or more: 0⋅50, 95 % CI 0⋅27, 0⋅93, P = 0⋅029). After stratifying for fruit consumption (Pinteraction between tea and fruit = 0⋅007), consuming four cups of tea per day was nominally associated with lower incidence of metabolic syndrome among those with high fruit consumption (multivariable-adjusted HR: 0⋅44, 95 % CI 0⋅20, 0⋅93, P = 0⋅033). Our results did not support a significant association between tea and coffee consumption and metabolic syndrome. Tea consumption may be associated with a lower risk of having low HDL-C, while high tea and fruit consumption together may be associated with a lower risk of developing metabolic syndrome.
Adequacy of antenatal care services utilisation and its effect on anaemia in pregnancy
Authors: Saapiire Ferguson , Dogoli Richard , Mahama Saaka 
Published: September 2022

Abstract
Anaemia in pregnancy remains a critical public health concern in many countries including Ghana and it poses severe consequences in the short to long-term for women and their unborn babies. Although antenatal care (ANC) is largely provided for pregnant women, the extent its utilisation protects against anaemia in pregnancy remains largely understudied. The study assessed the adequacy of ANC services utilisation and its effect on anaemia among pregnant women in the Wa Municipality of Ghana. A facility-based cross-sectional survey was conducted. Probability proportionate to size sampling and systematic random sampling were used to select the facilities and 353 respondents. While 80⋅2 % of the pregnant women reported having received a sufficient number of ANC services provided, the prevalence of the overall ANC adequacy was only 44⋅2 %. After adjusting for potential confounders, pregnant women who could not achieve adequate ANC attendance were 2⋅3 times more likely to be anaemic in the third trimester of gestation AOR = 2⋅26 (95 % CI 1⋅05, 4⋅89), compared to their counterparts who maintained adequate ANC attendance. Adequate ANC attendance was a consistent and significant predictor of anaemia in pregnancy in the third trimester. Health and nutrition education on the need for early initiation of ANC attendance and support for the consumption of diversified diets are two possible interventions that can help contain anaemia in pregnancy.
An exploration into the impact that shift work has on the nutritional behaviours of UK police officers
Authors: Allen Katie , Safi Ayazullah , Deb Sanjoy K. 
Published: September 2022

AbstractPolice officers are at high risk of developing obesity and cardiometabolic health conditions. Their job presents challenges that contribute to this, predominantly shift work, which causes circadian misalignment and can impair metabolism. Food consumption plays a critical role in the synchronisation of the circadian system. Thus, the aim of this study was to understand the barriers and the impact that different shift types have on the dietary habits of police officers in the UK. A concurrent mixed-methods design was used through an online survey that was open to all police officers who were currently working shifts in the UK. One hundred and twenty-seven police officers were included in the analysis. Diet quality was significantly worse on all shift types than on rest days (P < 0·001) and was negatively correlated with BMI on all shifts: early shift (= −0·29, P = 0·001), late shift (rs(105) = −0·25, P = 0·009), nightshift (rs(104) = −0·24, P = 0·013) and rest days (rs(117) = −0·31, P = 0·001). Participants reported that shift work had altered their frequency and timing of food consumption and had increased their reliance on convenience and poor-quality food. Barriers to healthy eating included lacking time (87 %), motivation (65 %) and cost (48 %). Convenience was ranked the highest influence on food choice (49 %), followed by price (41·5 %). Police officers are faced with unavoidable challenges when it comes to eating healthily. Future police-specific dietary interventions are required, providing practical solutions to these barriers so that behaviour change is more likely to be implemented.
Udder health of dairy cows with an extended voluntary waiting period from calving until the first insemination
Authors: Ma Junnan , Kok Akke , Goselink Roselinde M. A. , Lam Theo J. G. M. , Kemp Bas , van Knegsel Ariette T. M. 
Published: September 2022

AbstractThis study aimed to evaluate the effect of an extended voluntary waiting period (VWP) on SCC, SCC elevations and clinical mastitis incidence during the complete lactation and the first 6 weeks of the next lactation. Holstein-Friesian dairy cows (N = 154) were blocked for parity, expected milk yield, calving season and breeding value for persistency and were randomly distributed across 3 VWP (50, 125, or 200 d: VWP-50, VWP-125, VWP-200). Cows were monitored from calving until 6 weeks into the next lactation, or until culling. An elevation of SCC in milk was defined as SCC in milk ≥200 000 cells/ml after two previous weeks with SCC < 200 000 cells/ml. Over the complete lactation, extending the VWP did not affect SCC elevations and the occurrence of clinical mastitis per lactation or per cow per year. There was no clear effect of VWP length on SCC in the complete lactation, except that multiparous cows in VWP-125 had a higher SCC compared with multiparous cows in VWP-50. Dry-off antibiotic usage per cow per year was lower in VWP-200 compared with VWP-50 for multiparous cows. In the first 6 weeks of the next lactation, cows in VWP-200 had a higher SCC compared with cows in VWP-50, with no effect of VWP on the number of elevations of SCC or the occurrence of clinical mastitis. Extending the VWP may therefore be used to reduce the frequency of transition periods and the associated use of dry-cow antibiotics, with limited impact on udder health, and a similar occurrence of SCC elevations and clinical mastitis per year.
Neonatal withdrawal syndrome following in utero exposure to antidepressants: a disproportionality analysis of VigiBase, the WHO spontaneous reporting database
Authors: Gastaldon C. , Arzenton E. , Raschi E. , Spigset O. , Papola D. , Ostuzzi G. , Moretti U. , Trifirò G. , Barbui C. , Schoretsanitis G. 
Published: September 2022

AbstractBackgroundEvidence on neonatal withdrawal syndrome following antidepressant intrauterine exposure is limited, particularly for antidepressants other than selective serotonin reuptake inhibitor (SSRIs).MethodsIn our case/non-case pharmacovigilance study, based on VigiBase®, the WHO database of suspected adverse drug reactions, we estimated reporting odds ratio (ROR) and the Bayesian information component (IC) with 95% confidence/credibility intervals (CI) as measures of disproportionate reporting of antidepressant-related neonatal withdrawal syndrome. Antidepressants were first compared to all other medications, then to methadone, and finally within each class of antidepressants: SSRIs, tricyclics (TCA) and other antidepressants. Antidepressants were ranked in terms of clinical priority, based on semiquantitative score ratings. Serious v. non-serious reports were compared.ResultsA total of 406 reports of neonatal withdrawal syndrome in 379 neonates related to 15 antidepressants were included. Disproportionate reporting was detected for antidepressants as a group as compared to all other drugs (ROR: 6.18, 95% CI 5.45–7.01, IC: 2.07, 95% CI 1.92–2.21). Signals were found for TCAs (10.55, 95% CI 8.02–13.88), followed by other antidepressants (ROR: 5.90, 95% CI 4.74–7.36) and SSRIs (ROR: 4.68, 95% CI 4.04–5.42). Significant disproportionality emerged for all individual antidepressants except for bupropion, whereas no disproportionality for any antidepressant was detected v. methadone. Eleven antidepressants had a moderate clinical priority score and four had a weak one. Most frequent symptoms included respiratory symptoms (n = 106), irritability/agitation (n = 75), tremor (n = 52) and feeding problems (n = 40).ConclusionsMost antidepressants are associated with moderate signals of disproportionate reporting for neonatal withdrawal syndrome, which should be considered when prescribing an antidepressant during pregnancy, irrespective of class.
Wirken Online-Peer-Suizidpräventionsprogramme?
Authors: Hildebrand Anja , Weiss Maren , Braun-Scharm Hellmuth , Stemmler Mark 
Published: September 2022

Zusammenfassung. Theoretischer Hintergrund. Suizid ist weltweit die zweithäufigste Todesursache bei jungen Menschen. Es scheint sinnvoll, speziell auf diese Zielgruppe zugeschnittene Angebote anzubieten. Fragestellung. Ziel dieser Untersuchung ist, den von den Nutzenden wahrgenommenen Beratungserfolg eines Online-Peer-Suizidpräventionsprogramms zu ermitteln und zu prüfen, welche Merkmale mit dem Beratungserfolg zusammenhängen. Methode. Daten eines Online-Fragebogens wurden ausgewertet ( N = 318). Ergebnisse. Bei zwei Drittel der Befragten verminderte sich die Suizidalität. Wichtige Variablen zur Vorhersage der Veränderung der Suizidalität waren der Eindruck der Ratsuchenden, dass die Peers die persönlichen Anliegen verstehen und die Anregung zu einer Verhaltensänderung. Das Peerverhalten trug signifikant zur Vorhersage der subjektiven Nützlichkeit und der allgemeinen Situation bei. Schlussfolgerungen. Die Studie liefert positive Ergebnisse hinsichtlich der Evaluierung der Online-Suizidpräventions-Beratung. Da das Verstanden fühlen und das Peerverhalten im Zusammenhang mit dem Beratungserfolg steht, könnte der Peer-Ansatz und die damit einhergehende positive Beziehungserfahrung wichtig sein.
Influence of Snowpack Cold Content on Seasonally Frozen Ground and Its Hydrologic Consequences: A Case Study From Niwot Ridge, CO
Authors: Rush M. J. , Rajaram H. 
Published: September 2022

AbstractFrozen ground influences subsurface hydrology by reducing soil permeability, impeding infiltration, and inducing surface runoff. As the seasonal snowpack strongly controls the evolution of the ground thermal regime, it is necessary to represent the snowpack in models simulating frozen ground and its hydrologic consequences. Conventional understanding of the relationship between snowcover and frozen ground considers the snowpack as an insulator, shielding the ground from cold winter temperatures and thus inhibiting frozen ground. However, observations and modeling at Niwot Ridge, a seasonally snow‐covered alpine catchment in the headwaters of the Boulder Creek watershed, illustrate that snowpack cold content can promote and preserve frozen ground beneath the snowpack during the snowmelt season, unlike bare ground patches that thaw relatively rapidly due to exposure to solar radiation and warm spring temperatures. We present results from a coupled snowpack and subsurface thermo‐hydrologic model including freeze‐thaw processes that captures these contrasts reasonably well. Our results suggest that the cold snowpack at this site acts as a heat sink and promotes frozen ground, in contrast to the conventional understanding of the snowpack as an insulator. In the subalpine zone, infiltration simulations show that shallow freezing beneath snow‐covered ground has a much stronger effect on infiltration than shallow freezing beneath bare ground because the soil beneath the snow remained frozen during snowmelt, whereas bare patches thawed by the time they received excess snowmelt run‐on.
Magmatic Carbon and Helium in Springs Reveals the Vitality of a Dormant Volcano, Taranaki, New Zealand
Authors: Werner C. , Schipper C. I. , Cronin S. J. , Barry P. H. , Stewart M. K. 
Published: September 2022

AbstractA challenge in monitoring long‐dormant volcanoes is to discover early signs of reawakening. Mineral springs on Taranaki volcano (2,518 m, New Zealand) have elevated carbonate concentrations, δ13CDIC ∼ −5‰ (VPDB) and He isotopes from 5.13 to 5.92 RA, indicating a magmatic volatile source. Stable isotopes demonstrate water recharge occurs near the volcano's summit. Volatile anions and silica are low in a cold (5oC) flank spring at 1,000 m a.s.l., yet elevated in warm springs (25–32oC) associated with travertine deposits at 250–300 m, suggesting a weak hydrothermal component along the flow path. Tritium dating of the cold spring water yields a mean residence time of 7.8 years. This short residence time and magmatic volatile signatures suggest magmatic CO2 persistently flushes Taranaki's upper edifice. Cold spring geochemistry thus reveals volcanic activity at this dormant volcano that otherwise lacks obvious geophysical signs of unrest.
Meridional Propagation of Carbon Dioxide (CO2) Growth Rate and Flux Anomalies From the Tropics Due to ENSO
Authors: Das Chiranjit , Kunchala Ravi Kumar , Chandra Naveen , Chmura Lukasz , Nęcki Jarosław , Patra Prabir K. 
Published: September 2022

AbstractEl Niño Southern Oscillation (ENSO) influence on carbon dioxide (CO2) growth rates are not spatially uniform or simultaneous around the globe. Using atmospheric CO2 observations and atmospheric chemistry‐transport model (ACTM), we show that anomalies in CO2 fluxes and growth rate originate in the tropics, as an effect of ENSO. The CO2 anomalies are then propagated from the equator toward the poles with asymmetric delays. A maximum delay of about 8 and 4 months are found at the northern hemisphere (NH) and southern hemisphere (SH) high latitudes, respectively. This asymmetric time delay is because of the CO2 flux anomaly mainly originate in the tropical SH land and transport of SH air into the NH is slower than that for NH air into the SH. The poleward increase of time delay is more homogeneous in the upper troposphere, as per the ACTM simulations, but observational evidence suffers from gaps in long‐term measurements.
An Improved and Observationally‐Constrained Melt Rate Parameterization for Vertical Ice Fronts of Marine Terminating Glaciers
Authors: Schulz K. , Nguyen A. T. , Pillar H. R. 
Published: September 2022

AbstractSubmarine melting at Greenland's marine terminating glaciers is a crucial, yet poorly constrained process in the coupled ice‐ocean system. Application of Antarctic melt rate representations, derived for floating glacier tongues, to non‐floating marine terminating glaciers commonly found in Greenland, results in a dramatic underestimation of submarine melting. Here, we revisit the physical theory underlying melt rate parameterizations and leverage recently published observational data to derive a novel melt rate parameterization. This is the first parameterization that (a) consistently comprises both convective‐ and shear‐dominated melt regimes, (b) includes coefficients quantitatively constrained using observational data, and (c) is applicable to any vertical glacier front. We show that, compared to the current state‐of‐the‐art approach, the scheme provides an improved fit to observed melt rates on the scale of the terminating front, offering an opportunity to incorporate this critical missing forcing into ocean circulation models.