bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing the influence of migraine on stroke ischemic penumbra
Authors: Oliveira Felipe Araújo Andrade de , Dourado Filho Mario Genuíno , Rocha-Filho Pedro Augusto Sampaio 
Published: November 2022

Abstract
Introduction
There is controversy as to whether migraine affects the behavior of ischemic penumbra during the acute phase of an ischemic stroke, thereby accelerating the formation of cerebral infarction.
Objectives
To assess whether migraine modifies the existence and volume of the divergence between the areas of diffusion and perfusion in the stroke (the penumbra).
Methods
This was a prospective cohort study carried out in a hospital in the city of Recife, Pernambuco, Brazil. We included consecutively hospitalized patients with ischemic stroke within 72 hours of symptom onset. A diagnosis of ischemic stroke was made by the presence of a diffusion restriction pattern on the MRI within a compatible clinical context. Patients were assessed by a neurologist who conducted an interview using a semi-structured questionnaire containing questions regarding sociodemographic data, the presence and characteristics of headaches in their lives, the presence and characteristics of headaches related to ischemic stroke and the related clinical condition to ischemic stroke. The headaches presented were classified according to the diagnostic criteria of the third edition of the International Classification of Headache Disorders. The National Institute of Health Stroke Scale and the modified Rankin scale were used. Patients underwent MRI of the brain with diffusion and with perfusion.
Results: A total of 221 patients were included, 59.3% of whom were male, and a mean age of 68.2 ± 13.8 years. Ischemic penumbra analysis was performed in 118 patients. There was no association between migraine and the absence of ischemic penumbra (OR: 1.22; CI95%: 0.52 – 2.87; p=0.649; Chi-Square Test). There was no difference in the volume of ischemic penumbra between those with and without migraine. There was no difference in stroke volume between those with and without migraine (1.0; 0.38 – 7.9 cm3...
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Caliber and type of needle are associated with the risk of spontaneously reported post-dural punction headache
Authors: Domingues Renan , Vega Márcio , Giafferi Carlos , Brunale Fernando , Senne Carlos 
Published: November 2022

Introduction
Post-dural punction headache (PDH) is defined as an orthostatic headache that develops within the first few days after performing a spinal tap and it is related to extravasation of cerebrospinal fluid (CSF) into the epidural space, resulting in hypovolemia and CSF hypotension. The risk factors for PDH are not yet fully understood.
Objective
To evaluate the risk of spontaneously reported PDH according to the size and type of spinal tap needle.
Methods
A total of 4589 patients undergoing outpatient lumbar puncture were included. All CSF collections were performed at Senne Liquor Diagnostico, a laboratory specialized in CSF collection and analysis. Patients were instructed to report by telephone the onset of orthostatic headache during the first 7 days after the puncture to the medical team of the laboratory. Patients with previous headache were instructed to report any change in the headache pattern during the same period.
Needle gauge was classified into two groups: 1) 25G or less and 2) greater than 25G. Two types of needles were used and compared: 1) Pencil point and 2) Quincke.
Comparisons of the percentages of spontaneous reports of PDH were made using the chi-square test.
Results
141 patients (3.07%) reported PHD to the laboratory's medical team. Needles of 25G gauge or less were used in 31.8% of cases. The percentage of patients reporting PHD in the group of 25G or less needles was 1.9% versus 3.6% in the group of greater than 25G needles (P=0.003). Pencil point needles were used in 10.6% of cases. The percentage of PHD among pencil point group was 1.4% versus 3.2% in Quincke group (P=0.026).
Conclusion
25G or finer gauge needles as well as pencil point type needles significantly reduced the risk of spontaneously reported PHD.
Key-words:
Post-dural punction headache, Spinal Tap, Spinal Tap Needle.
Spontaneous intracranial hypotension syndrome presented with sixth cranial nerve palsy: a case report
Authors: Sousa-Santos Patrick Emanuell , Pozzobon Pedro Machry , Lemos Ana Flavia Andrade , Vieigas Caroline , Junior Gilberto Magioni , Alvarenga Tarcísio Nunes , Teixeira Igor de Lima e , Lopes Laura Cardia 
Published: November 2022

Introduction
Spontaneous intracranial hypotension (SIH) is a secondary cause of headache often misdiagnosed and underdiagnosed disorder. The main presentation is orthostatic headache. An uncommon symptom is cranial nerve palsy. We described a case of SIH that presented to our service with sixth cranial nerve palsy.
Case Report
Female, 39 years old, no relevant medical past or history of trauma, awoke due intense holocranial headache, associated with vomiting and photophobia, worsening in orthostasis. In the general emergency department, she was release with prescription of analgesics and topiramate, without resolution. After a week, the patient reported diplopia and was referred to our service, a tertiary center. In admission, she kept an intense orthostatic headache and in neurologic examination she presented right sixth nerve palsy, no other deficits. Laboratorial tests were normal, including metabolic and infectious marks. Cerebrospinal fluid (CSF) opening pressure was low (50 mmH2O) and analysis showed elevated protein levels (158mg/dl). MRI showed diffuse pachymeningeal enhancement and venous sinus distension, mainly in superior sagittal venous sinus. CT myelogram detected a spinal CSF leak in transition C1-C2. Initially, performed hydration and bed rest, while patient with partial improvement of headache. An epidural blood patch was then performed using 15ml of autologous blood with compatible contrast and lidocaine. There was complete resolution of pain after the procedure and four weeks later complete resolution of right sixth nerve palsy.
Discussion
According to International Classification of Headaches Disorders, third edition (ICHD-3), the headache attributed to SIH is descripted as a headache has developed in temporal relation to low CSF pressure (<60mm H2O) and/or evidence of CSF leakage on imaging.

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Executive and attentional functions in patients with migraine
Authors: Jurno Mauro , Magierek Valeska , Carvalho Letícia Silva Gomes de , Assis Camila Gualberto Bernardes de 
Published: November 2022

Introduction
The Executive Functions (EF) allow the individual to direct behaviors to the goal, evaluate his/her efficiency and appropriateness, and eliminate ineffective strategies by other efficient and functional ones to solve short, medium, and long-term problems. To this end, attention is fundamental to learning and problem solving.
Objective
To relate executive and attentional functions with the presence or absence of migraine.
Methods
A cross-sectional study on the presence of attentional and EF alterations in migrant patients, with a target sample of 42 subjects, 30 migrants and 13 non-migrants. Subjects above eighteen (18) years of age, recruited consecutively by convenience at the Centro Acadêmico Multiprofissional Dr. Agostinho Paolucci of the Faculdade de Medicina de Barbacena - CAM FAME, Faculdade de Medicina and Centro AMA de Desenvolvimento, were included in the study, regardless of sex, after completion of the free and informed consent form - FICF. Subjects with migraine were in accordance with the criteria of the International Classification of Headaches (ICHD-3). All subjects diagnosed with migraine and undergoing neuropsychological evaluation were included. The Psychological Attention Assessment Battery (APB) was used for the attention test and the Five Digits Test was used for the EF test. The APB measures the attentional performance in 3 (three) distinct types of attention, related to 1) the ability to maintain the focus of attention on a given stimulus for a prolonged time; 2) the ability to distribute attention resources for the simultaneous execution of multiple tasks; 3) the ability to alternate attention resources among different stimuli. The Five Digits Test verifies the speed of reasoning and response, its accuracy and assertiveness, and can also be used as a measure of attentional processes and their accuracy.
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Electrochemical Corrosion Studies of Low-Alloyed Carbon Steel in Acidic Methylimidazolium Derivate Ionic Liquids with Varying Water Content
Authors: Lukács Zoltán , Molnár Ferenc , Skoda-Földes Rita , Hancsók Jenő , Kristóf Tamás 
Published: November 2022

The application of ionic liquids (ILs) in a wide range of technologies requires a thorough evaluation of their corrosion behavior to typical structural steels. In this work, the corrosion effects of two acidic-type methylimidazolium derivates (potential catalyst candidates) on low-alloyed carbon steel were studied with electrochemical methods (potentiodynamic polarization and electrochemical impedance spectroscopy [EIS]). The ILs cause moderate corrosion around 0.1 mm/y at water content up to 10‰ and severe corrosion around 1 mm/y at 100‰, which underlines that before industrial applications of ILs systematic corrosion studies should be performed as part of the process design. With both ILs we found that the cathodic process exhibited apparently good linear Tafel slopes in the cathodic polarization range but in the anodic range the IL with the hydrogensulfate anion showed an active-passive transition only at the highest water concentration. In this series at lower water concentrations, under 100‰, a model assuming a potential-independent anodic current rate correctly matched with the polarization data. The EIS measurement data showed chaotic, but reproducible deviations in the low-frequency range, which were interpreted as the effect of the timely variation of distribution parameters and they apparently did not affect the charge transfer parameters essentially.
Evaluasi Program Tri Dharma Dalam Upaya Penigkatan Mutu Pendidikan STAI Jam’iyah Mahmudiyah Langkat
Authors: Ahmad Zaki, Novira Arafah Muamar Al-Qadri, 
Published: November 2022

Dalam dunia pendidikan di perguruan tinggi, tenaga pengajar tidak hanya dibebankan pada aspek pengajaran saja, tetap juga dititik beratkan pada aspek penelitian dan pengabdian kepada masyarakat. Ketiga hal tersebut telah terangkum dalam istilah tri dharma. Dengan demikian, dosen sebagai pengajar di pendidikan tinggi melakukan kewajiban mengajarnya sesuai dengan jumlah SKS yang diampunya, kemudian disisi lain juga melakukan penelitian sesuai dengan fenomena dan fakta lapangan yang diamatinya serta tak lupa mengadakan pengabdian kepada masyarakat baik di lingkungan tempat tinggalnya, pendidikan/pekerjaannya, hingga masyarakat yang menurutnya layak untuk diberikan pengabdian kepadanya. Penelitian ini bertujuan: (1) Untuk mengetahui implementasi dan capaian program tri dharma di STAI Jam’iyah Mahmudiyah Langkat, (2) Untuk mengetahui mutu pendidikan di STAI Jam’iyah Mahmudiyah Langkat, (3) Untuk mengetahui peran SDM dalam peningkatan mutu di STAI Jam’iyah Mahmudiyah Langkat. Penelitian ini merupakan jenis penelitian lapangan dengan pendekatan kualitatif. Lokasi penelitian di STAI Jam’iyah Mahmudiyah Langkat, dengan subyek penelitian: LPM, LPPM, Dosen dan Mahasiswa, dengan metode pengumpulan data: obeservasi, wawancara dan dokumentasi. Evaluasi Program terdiri dari evaluator dan evaluated. Secara sistematis, evaluasi program yang dijalankan di STAI-JM meliputi keseluruhan elemen yang dilakukan melalui SPMI (Sistem Penjaminan Mutu Internal). Tri Darma Perguruan Tinggi mencakup 3 pilar, yakni: pendidikan dan pengajaran, penelitian dan pengabdian kepada masyarakat. Mutu pendidikan dapat dicapai dengan pilar-pilar yang telah dipaparkan di atas, sebagai sub pokok yang paling urgensi dalam lingkup Perguruan Tinggi. Telah diketahui bahwasannya dosen cukup aktif dalam pendidikan, penelitian dan pengajaran.
Mogamulizumab (Poteligeo)
Authors: CADTH  
Published: November 2022

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses Mogamulizumab (Poteligeo), 20 mg/5 mL single-use vial IV infusion, 4 mg/mL.
Indication: For the treatment of adult patients with relapsed or refractory MF or SS after at least 1 prior systemic therapy.
Improving interpretation of sea-level projections through a machine-learning-based local explanation approach
Authors: Rohmer Jeremy , Thieblemont Remi , Le Cozannet Goneri , Goelzer Heiko , Durand Gael 
Published: November 2022

Abstract. Process-based projections of the sea-level contribution
from land ice components are often obtained from simulations using a complex
chain of numerical models. Because of their importance in supporting the
decision-making process for coastal risk assessment and adaptation,
improving the interpretability of these projections is of great interest. To
this end, we adopt the local attribution approach developed in the machine
learning community known as “SHAP” (SHapley Additive exPlanations). We apply
our methodology to a subset of the multi-model ensemble study of the future
contribution of the Greenland ice sheet to sea level, taking into account
different modelling choices related to (1) numerical implementation, (2) initial conditions, (3) modelling of ice-sheet processes, and (4) environmental forcing. This allows us to quantify the influence of
particular modelling decisions, which is directly expressed in terms of sea-level change contribution. This type of diagnosis can be performed on any
member of the ensemble, and we show in the Greenland case how the
aggregation of the local attribution analyses can help guide future model
development as well as scientific interpretation, particularly with regard
to spatial model resolution and to retreat parametrisation.
A RECENTLY DISCOVERED TRACHYTE-HOSTED RARE EARTH ELEMENT-NIOBIUM-ZIRCONIUM OCCURRENCE IN NORTHERN MAINE, USA
Authors: Wang Chunzeng , Slack John F. , Shah Anjana K. , Yates Martin G. , Lentz David R. , Whittaker Amber T.H. , Marvinney Robert G. 
Published: November 2022

AbstractReported here are geological, geophysical, mineralogical, and geochemical data on a previously unknown trachyte-hosted rare earth element (REE)-Nb-Zr occurrence at Pennington Mountain in northern Maine, USA. This occurrence was newly discovered by a regional multiparameter, airborne radiometric survey that revealed anomalously high equivalent Th (eTh) and U (eU), confirmed by a detailed ground radiometric survey and by portable X-Ray fluorescence (pXRF) and whole-rock analyses of representative rock samples. The mineralized area occurs within an elongate trachyte body (~1.2 km2) that intrudes Ordovician volcanic rocks. Geologic constraints suggest that the trachyte is also Ordovician in age. The eastern lobe (~900 × ~400 m) of the trachyte is pervasively brecciated with a matrix containing seams, lenses, and veinlets composed mainly of potassium feldspar, albite, and fine-grained zircon and monazite. Barite is locally abundant. Minor minerals within the matrix include columbite, bastnäsite, euxenite, chlorite, pyrite, sphalerite, and magnetite. The pXRF analyses of 22 samples (App. Table A1) collected from the eastern lobe demonstrate that this entire part of the trachyte is highly mineralized. Whole-rock geochemical analyses for samples from the eastern lobe document high average contents of Zr (1.17 wt %), Nb (1,656 ppm), Ba (3,132 ppm), Y (1,140 ppm), Hf (324 ppm), Ta (122 ppm), Th (124 ppm), U (36.5 ppm), Zn (689 ppm), and Sn (106 ppm). Among light REE, the highest average concentrations are shown by La (763 ppm) and Ce (1,479 ppm). For heavy REE (HREE), Dy and Er are the most abundant on average (167 and 114 ppm, respectively). No HREE-rich minerals such as xenotime have been identified; the HREE may reside chiefly in monazite and bastnäsite, and within the fine-grained zircon. Very strong positive correlations (R2) of 0.92 to 0.98 exist between Th and Zr, Nb, Y, Ce, Yb, and Sn, indicating that the radiometric data for eTh are valid proxies for concentrations of these metals in the mineralized rocks.Trachyte-hosted REE-Nb-Zr deposits like the occurrence at Pennington Mountain also are known in eastern Australia and in the south Qinling belt of Central China. Based on comparisons with these deposits, and the lack of detailed geologic mapping in the Pennington Mountain region, we suggest that other rare-metal occurrences contained in trachyte may exist elsewhere in northern Maine, and more widely in the Appalachian-Caledonian orogen where volcanic and subvolcanic trachytes have been recognized.
Contextual Framework of the Generation Effect
Authors: McCurdy Matthew P. , Leshikar Eric D. 
Published: November 2022

AbstractIn the modern era of psychology, researchers have used experiments to increase understanding of human memory, leading to the discovery of many memory phenomena. One example is the generation effect, where self-generating information often improves later memory for that information compared to reading. However, general assertions about memory such as the generation effect are often limited by boundary conditions, or situations where these effects no longer hold true (e.g., generating does not lead to better memory than reading). These boundary conditions indicate that memory is context sensitive, yet too often contextual experimental factors are neglected when researchers are designing studies and interpreting empirical data. In this article, we develop a contextual framework of the generation effect that describes experimental conditions that lead to increased or decreased memory performance by considering the interactions between four key experimental factors: encoding task, memory test, materials used in the experiment, and subject abilities. We present testable predictions generated by the framework, highlight the flexibility of this framework, and discuss avenues for future research. Overall, we argue that this framework can more fully account for a wide range of findings on the generation effect by expanding on existing multifactor theories attempting to explain the effect and its boundary conditions. This framework illuminates the need to investigate higher-order interactions between 4 key experimental factors to advance our understanding of the complex nature of the generation effect and human memory.
House of Cards
Authors: Goudsouzian Aram 
Published: November 2022

Abstract
Landon Carter, a wealthy planter in the Tidewater of Virginia during the eighteenth century, kept a diary that possesses great value for scholars of sport history. His writings showcase a wide emotional range, including white-hot rage and bubbling pathos. In his diary, Carter often decried the leisure habits of others, especially his son Robert Wormeley Carter, who constantly gambled on horses and cards. For Landon, if leisure was allowed to run wild, it threatened republican virtue, which was the basis of social authority and political power. Although Carter's diary is limited to the perspective of an elite, white, male planter from Virginia, his worldview was shaped by the assumptions of patriarchy and the institution of slavery. His lamentations about rampant games reflected his worries about his own corroding paternal authority—a private drama amid his larger, public anxieties about a crumbling social order during the era of the American Revolution.
The People of Hamtramck: Some Reflections on Belonging, Agency, and Being Polish American
Authors: Müller Anna 
Published: November 2022

Abstract
This article presents a selective portrayal of the Polish Americans of Hamtramck based on a collection of oral interviews conducted in the summers of 2014 and 2015. It argues that Hamtramck is best understood through the concept of “tangible belonging,” which historian John Swanson defines as an identity that is built in connection with a mental construct derived from the tactile environment in which an individual lives and experiences through the various senses of vision, sound, smell, touch, and so forth. Each generation and wave of immigrants understood differently their Polish and Polish American identity, which developed via a complex connection with Hamtramck's fabric of life over the years.
Enkele opmerkingen bij strafvorderlijke kort gedingen over de Caribische strafexecutie
Authors: Pesselse G. 
Published: November 2022

Enkele opmerkingen bij strafvorderlijke kort gedingen over de Caribische strafexecutie
Artikel 43 van de Wetboeken van Strafvordering van Aruba, Curaçao en Sint Maarten (hierna: CSv) regelt de rechterlijke voorziening bij dringende noodzaak, ook wel het strafvorderlijk kort geding genoemd. Het Gemeenschappelijk Hof publiceerde onlangs in kort bestek vijf min of meer recente beslissingen in dergelijke kort gedingen. Alle zaken betroffen de executie van strafrechtelijke sancties. De vijf beschikkingen bieden niet alleen enkele aardige luiken op het Caribische penitentiaire recht, maar brengen ook de bijzondere figuur van het strafvorderlijk kort geding onder de aandacht, en verdienen om die redenen een bespreking in dit blad.
Alternatieve regeling voor homoparen die gelijkwaardig is aan het huwelijk voor heteroparen
Authors: Ismail R.R. 
Published: November 2022

Alternatieve regeling voor homoparen die gelijkwaardig is aan het huwelijk voor heteroparen
Niet openstellen van huwelijk voor paren van gelijk geslacht althans geen gelijkwaardig alternatief aanbieden in de vorm van een geregistreerd partnerschap; strijdigheid van artikel 1:30 lid 1 BW Curaçao met artikel 3 Staatsregeling en artikel 1:31 lid 1 BW Aruba met artikel 8 en 14 EVRM.