bluuebunny/crossref_metadata_2025_split huggingface dataset:
Virtual cancer multidisciplinary team meetings: outcomes of a two-phased survey from a tertiary NHS hospital
Authors: Gupta Madhumita , Maamoun Wareth 
Published: July 2022

Background/Aim Multidisciplinary team meetings have been an integral part of comprehensive cancer services in the UK for over 20 years. The COVID-19 pandemic led to the adoption of virtual platforms to allow these meetings to continue with minimal in-person contact. This study assessed multidisciplinary team members’ perspectives regarding the efficacy of the virtual platform, with the view of continuing this mode of delivery in the post-pandemic world. Methods A two-phased survey study was conducted among all members of the cancer multidisciplinary team in one UK hospital. Respondents completed a four-part questionnaire 6 months (n=108) and 1 year (n=120) after the implementation of the virtual platform in March 2020 to determine their perceptions of its effectiveness and safety. Results There was a statistically significant (P<0.05) improvement between the 6-month and 1-year survey responses in terms of overall satisfaction with the virtual platform, ease of use and efficiency of collective decision making using the virtual format. After 1 year, 80.5% of respondents preferred either continuing to use the virtual platform exclusively or switching to a hybrid model. Conclusions Staff experiences of using a virtual platform for cancer multidisciplinary team meetings may improve over time, with many respondents preferring this mode of delivery. Virtual meetings can provide greater flexibility and allow wider participation, potentially including specialists from across the globe.
Adjustment and wellbeing among people with end-stage chronic kidney disease receiving in-centre haemodialysis during the COVID-19 pandemic
Authors: Elander James , Kapadi Romaana , Danton Ian , Louth Charlotte , Selby Nicholas M , Taal Maarten W , Stalker Carol , Mitchell Kathryn 
Published: July 2022

Background: Many people with end-stage chronic kidney disease continued attending clinical centres for dialysis despite the risk of contracting COVID-19 and developing severe disease. Aims: To assess the impact of COVID-19 on patients' adjustment and wellbeing. Methods: Some 40 people (18 female, 22 male) receiving in-centre haemodialysis reported COVID-19-related adverse impacts on treatment and rated their COVID-19-related concerns, then completed the Depression, Anxiety and Stress Scale-21 and four scales of the Kidney Disease Quality of Life Short Form. Findings: The most common adverse impacts were staff shortages/changes and impaired interaction with staff/patients. Of the sample, 32.4% were severely depressed, 14.7% severely anxious and 18.9% severely stressed. Participants who had tested positive for COVID-19 were more depressed and reported more adverse impacts. Older and married/cohabiting participants had better adjustment and wellbeing. Conclusions: The results help to identify patients with the greatest needs and suggest ways to maintain patient wellbeing during outbreaks of infectious disease.
When time does not heal all wounds—the use of medical grade honey in wound healing: a case series
Authors: Naik Piyu Parth , Chrysostomou Daniela , Cinteza Mirela , Pokorná Andrea , Cremers Niels AJ 
Published: July 2022

Objective: Hard-to-heal wounds can be caused by persistent infections or an excess of inflammatory cytokines, proteases and oxidants, and can severely impact the quality of life (QoL) of patients. Due to the paucity of effective treatments and increased resistance to antibiotics, new and improved therapies are required to resolve infections and to simultaneously enhance the healing trajectory. Medical grade honey (MGH) may be a novel and effective treatment approach. Methods: In this case series, we have described six cases of hard-to-heal wounds, and discussed the effects of MGH on infection, wound healing and factors influencing patient QoL (pain, odour and exudate). In all cases, the wounds had persisted for a long period, and previous treatments had been ineffective. Most of the patients had comorbidities, and the majority of the wounds were contaminated with (multiresistant) bacteria, both of which contributed to non-healing. All wounds were treated with L-Mesitran (MGH-based wound care products, Triticum Exploitatie BV, the Netherlands) either as monotherapy or as a complementary therapy. Results: Hard-to-heal wounds started healing, infection was controlled and QoL was strongly improved (malodour, exudate levels and pain swiftly decreased) after the application of the MGH. All wounds healed relatively quickly, considering the severity of the wounds and general health of the patients. Conclusion: In this study, MGH was a useful alternative or complementary therapy to antibiotics and expedited the healing of hard-to-heal wounds.
Integra Dermal Regeneration Template in reconstructive surgery for cutaneous tumours: a two-year retrospective review
Authors: Prezzavento Gustavo E , Calvi Rodrigo N Juarez , Rodriguez Juan A , Taupin Philippe 
Published: July 2022

Objective: Integra Dermal Regeneration Template (IDRT) (Integra LifeSciences, US) is a bioengineered dermal matrix that has been widely used in burn reconstruction since its first description. However, little is reported on its use in oncologic dermatological defects. Our objective was to evaluate reconstruction using IDRT on cutaneous tumour defects. Method: We conducted a two-year retrospective review of patients with skin tumours who had an excision surgery, followed by reconstruction with IDRT, as a mid-step towards a final autograft procedure: a split-thickness skin graft. The records of all patients at a single academic institution were queried from the electronic medical record using data obtained from the operating surgeon. Results: We identified 13 patients with different tumour types and locations. The mean defect size was 105.92cm². The matrix take rate was 92.3% and average postoperative day for definite autograft was 20 days. Patients were followed for a period of up to 12 months. Of the patients, one had exposed bone without periosteum; another patient showed recurrence six months after matrix placement, requiring a new second two-stage IDRT-autograft procedure before radiation therapy. Patients reported complete satisfaction with the cosmetic, functional and oncological results. No cases of infection were encountered. Conclusion: IDRT is a valid option for the reconstruction of oncologic surgical defects of the skin and can be used in different anatomical locations. Specifically, it is an alternative to the reconstructive ladder when grafts and local flaps are not possible in those patients, and an option for patients who will eventually need adjuvant radiotherapy.
Levels of secretory leukocyte protease inhibitor expression in acute wounds
Authors: Lai Jengyu , Basford Jeffrey R , Pittelkow Mark R 
Published: July 2022

Objective: Even with our best practices, we are frequently unable to prevent slow and stalled wound healing—particularly in people with impaired circulation and conditions such as diabetes. As a result, greater insight into the nature of wound healing and alternative treatment approaches is needed. An avenue that may be of particular promise is increasing understanding of the role of secretory leukocyte protease inhibitor (SLPI) as there is evidence that it enhances wound healing, its expression increases in response to inflammation and infection, and it exhibits anti-protease, anti-inflammatory, antiviral antibacterial and antifungal activities. Method: The response of SLPI levels to wounding and skin injury was assessed by taking punch skin biopsies from healthy volunteers and assessing the levels of SLPI at the site of injury at the time of wounding (baseline) as well as one, two, three, four, seven, nine and 12 weeks later. Results: A total of 35 volunteers took part in the study. Significant elevations were found: levels of SLPI were greatly increased, 12 times that at baseline, and remained elevated at three weeks despite re-epithelialisation having occurred. Conclusion: These findings not only suggest that levels of SLPI rise rapidly following wounding, but that these elevations are sustained, and continue to increase even when re-epithelialisation has occurred. These results suggest that the role and potential benefits of this protease inhibitor deserve further exploration.
New Work in der Praxis – Erfahrungen und Beispiele aus Unternehmen
Authors: Kohl Nina , Sperber Anna-Maria , Fehr Wolfang , Rapp Jochen 
Published: July 2022

ZusammenfassungMobiles Arbeiten oder die Zusammenarbeit in Büroräumen kann nur dann erfolgreich gestaltet werden, wenn diese durch optimale Technologien und die richtige digitale Transformation unterstützt werden. Die digitale Transformation ist dabei nicht nur ein technologischer, sondern vor allem ein kultureller Wandel. Organisationen müssen sich in Zukunft demnach die Frage stellen, welche kulturellen Veränderungen notwendig sind und wie diese durch entsprechende Technologien unterstützt werden können. Wir beobachten in diesem Zusammenhang, dass Unternehmen mit einem ganz unterschiedlichen Ausgangspunkt in die Krise gestartet sind – es gibt die einen Unternehmen, die bereits vor der Pandemie in ihre Digitalstrategie investiert haben, und die anderen Unternehmen, die vor der Pandemie nur wenig für die Digitalisierung ihrer Geschäftsprozesse unternommen haben.Anhand von Unternehmensbeispielen zeigt dieses Paper die Chancen aber auch Grenzen von Digitalisierung und New Work auf. Das Paper beschreibt zudem, welche aktuellen Veränderungen bei Unternehmen zu beobachten sind.
Direction of attentional focus in prosthetic training: Current practice and potential for improving motor learning in individuals with lower limb loss
Authors: Lee Szu-Ping , Bonczyk Alexander , Dimapilis Maria Katrina , Partridge Sarah , Ruiz Samantha , Chien Lung-Chang , Sawers Andrew 
Published: July 2022

Objective
Adopting an external focus of attention has been shown to benefit motor performance and learning. However, the potential of optimizing attentional focus for improving prosthetic motor skills in lower limb prosthesis (LLP) users has not been examined. In this study, we investigated the frequency and direction of attentional focus embedded in the verbal instructions in a clinical prosthetic training setting.

Methods
Twenty-one adult LLP users (8 female, 13 male; 85% at K3 level; mean age = 50.5) were recruited from prosthetic clinics in the Southern Nevada region. Verbal interactions between LLP users and their prosthetists (mean experience = 10 years, range = 4–21 years) during prosthetic training were recorded. Recordings were analyzed to categorize the direction of attentional focus embedded in the instructional and feedback statements as internal, external, mixed, or unfocused. We also explored whether LLP users’ age, time since amputation, and perceived mobility were associated with the proportion of attentional focus statements they received.

Results
We recorded a total of 20 training sessions, yielding 904 statements of instruction from 338 minutes of training. Overall, one verbal interaction occurred every 22.1 seconds. Among the statements, 64% were internal, 9% external, 3% mixed, and 25% unfocused. Regression analysis revealed that female, older, and higher functioning LLP users were significantly more likely to receive internally-focused instructions (p = 0.006, 0.035, and 0.024, respectively).

Conclusions
Our results demonstrated that verbal instructions and feedback are frequently provided to LLP users during prosthetic training. Most verbal interactions are focused internally on the LLP users’ body movements and not externally on the movement effects.

Impact statement
While more research is needed to explore how motor learning principles may be applied to improve LLP user outcomes, clinicians should consider adopting the best available scientific evidence during treatment. Overreliance on internally-focused instructions as observed in the current study may hinder prosthetic skill learning.
Prevalence of and risk factors for depression, anxiety, and stress in non-hospitalized asymptomatic and mild COVID-19 patients in East Java province, Indonesia
Authors: Lusida Michael Austin Pradipta , Salamah Sovia , Jonatan Michael , Wiyogo Illona Okvita , Asyari Claudia Herda , Ali Nurarifah Destianizar , Asmara Jose , Wahyuningtyas Ria Indah , Triyono Erwin Astha , Ratnadewi Ni Kadek , Irzaldy Abyan , Alkaff Firas Farisi 
Published: July 2022

BackgroundDespite abundant data on mental health during the COVID-19 pandemic, 3 important knowledge gaps continue to exist, i.e., 1) studies from low-/middle income countries (LMICs); 2) studies in the later period of the COVID-19 pandemic; and 3) studies on non-hospitalized asymptomatic and mild COVID-19 patients. To address the knowledge gaps, we assessed the prevalence of and the risk factors for mental health symptoms among non-hospitalized asymptomatic and mild COVID-19 patients in one LMIC (Indonesia) during the later period of the pandemic.MethodsThis cross-sectional study was conducted in September 2020 in East Java province, Indonesia. Study population consisted of non-hospitalized asymptomatic and mild COVID-19 patients who were diagnosed based on reverse transcriptase-polymerase chain reaction results from nasopharyngeal swab. Mental health symptoms were evaluated using the Depression Anxiety Stress Scale-21.ResultsFrom 778 non-hospitalized asymptomatic and mild COVID-19 patients, 608 patients were included in the analysis. Patients’ median age was 35 years old and 61.2% were male. Of these, 22 (3.6%) reported symptoms of depression, 87 (14.3%) reported symptoms of anxiety, and 48 (7.9%) reported symptoms of stress. Multivariate logistic regression analysis showed that females were more likely to report symptoms of stress (adjusted odds ratio (aOR) = 1.98, p-value = 0.028); healthcare workers were more likely to report symptoms of depression and anxiety (aOR = 5.57, p-value = 0.002 and aOR = 2.92, p-value = 0.014, respectively); and those with a recent history of self-quarantine were more likely to report symptoms of depression and stress (aOR 5.18, p = 0.004 and aOR = 1.86, p = 0.047, respectively).ConclusionThe reported prevalence of mental health symptoms, especially depression, was relatively low among non-hospitalized asymptomatic and mild COVID-19 patients during the later period of the COVID-19 pandemic in East Java province, Indonesia. In addition, several risk factors have been identified.
Is the Lexeme “Khach” Offensive?
Authors: Florya Alexandr 
Published: July 2022

The article discusses the study of the lexeme “khach” in the functional aspect. In forensic linguistics practice, one often has to deal with ethnopholisms. The lexeme “khach” is quite typical of controversial texts on ethnic topics. Its derogatory nature is not obvious to all forensic linguists. We consider this lexeme offensive and support our point of view. The author of the article disputes the phonosemantic interpretation of the negative attitude of native speakers to the lexeme “khach”: it seems to repel with its sound, unlike the name Ivan in the same function of the ethnonym. The author of the article gives examples of how the name Ivan evokes unpleasant emotions in a Russian person, as well as clearly positive connotations associated with names consisting of the same sounds as "khach". It is also impossible to agree with the opinion that the ethnonym “khach” is explained by the theory of lacunarity, that is, by the fact that there are no commonly used words to denote the residents of the Caucasus. Russian Russianодноубрать has the word “kavkazets” (Caucasian), which has not gone out of use at all, which is confirmed by the National Corpus of the Russian language. The lexeme “Khachik” is not pejorative but diminutive if it is a proper name. However, speakers avoid using even this form because of its negative associations. Generisizedvariants as unofficial names of an ethnic group or groups are delicts (torts), gross violations of speech etiquette. Morover, it does not necessarily refer to a certain – Armenian – people. In addition, such unofficial ethnonyms are associated with stereotypes, often derogatory for the named peoples.
Principles of Legal Responsibility: New Criteria for Classification and Subordination
Authors: Sorokin Vitaly , Stoilov Yanaki 
Published: July 2022

The article conseders the idea of the necessity of ranking the principles of legal responsibility. Conflict among the principles of legal responsibilities are inevitablin the process oftheir practical use. In this case, there should not be a compromise between legality and justice - a decision must be made in favor of justice. A conflict between justice and charity must be solved in favor of charity. Any conflicts among the principles of legal responsibility are hierarchical. Thus, any conflicts of principles of legal responsibility should be solved in favor of the principle of higher order.
L'enduit mural dans l'architecture otãmmari
Authors: Noukpakou Fabrice , Pauporté Elie 
Published: July 2022

Résumé. L'architecture otãmmari se distingue par les Tata Somba et de plus en plus par une pluralité d'habitats en terre crue. Ces bâtis se caractérisent par une vulnérabilité importante aux pluies qui, à défaut de travaux d'entretien réguliers, menacent leur durabilité. L'application d'un enduit de terre sur les parties extérieures de ces habitats joue un rôle fondamental, constituant la première protection contre les intempéries. Travail traditionnellement attribué aux femmes, cet enduisage témoigne d'un savoir-faire à la fois technique, par l'usage de divers adjuvants locaux (décoction de cosses de néré et résidu de karité) et esthétique par les décorations dont il fait l'objet (griffures).
Abstract. Otãmmari architecture is characterized by the Tata Somba and more and more by a plurality of earthen habitats. These buildings are characterized by significant vulnerability to heavy seasonal rain which, without regular maintenance, threatens their durability. The application of an earthen coating on the external parts of these habitats plays a fundamental role, constituting the primary protection against extreme weather. This work, traditionally attributed to women, demonstrates both technical knowhow, through the use of various local additives (decoction of néré pods and shea butter residue), and aesthetic practice, through the decoration of the plaster (scratching).
Income Losses, Cash Transfers and Trust in Financial and Political Institutions: Survey Evidence from the Covid-19 Crisis
Authors: Immordino Giovanni , Oliviero Tommaso , Zazzaro Alberto 
Published: July 2022

Abstract
Using a survey of Italian households, we find that large income losses suffered during the first wave of the Covid-19 pandemic in 2020 are associated with a decline in trust towards political (i.e. Italian Central Government and the EU Parliament) and financial (i.e. ECB and Italian commercial banks) institutions in the management of the Covid-19. The decline is lower for households who received public transfers in the wake of the pandemic. Our results highlight that household exposure to economic losses if not compensated by government income support measures are an important determinant of mistrust in institutions for the management of an economic crisis.
Evaluation of the effectiveness ofLactuca Sativasyrup in controlling pain after periodontal flap surgery: a split-mouth, randomized, double-blind placebo-controlled trial
Authors: Jafari Hadi , Latifi Seyed Amirhossein , Bayani Mojtaba 
Published: July 2022

AbstractObjectivesEffective pain control after oral surgeries including periodontal flap surgery is one of the biggest problems in the periodontology field. The use of Nonsteroidal Anti-inflammatory Drugs (NSAIDs) to reduce pain after periodontal flap surgery is common, but these have some adverse side effects such as impaired platelet function and causing digestive problems. Today, the tendency to use omedicinal plants is more than synthetic drugs due to their safety. Therefore, we designed a split-mouth randomized controlled clinical trial to evaluate the effects ofLactuca Sativa(L. Sativa) syrup as an adjunct therapy in reducing pain after periodontal flap surgery.MethodsThis split-mouth, randomized, double-blind, placebo-controlled trial was performed on 26 subjects. Patients were assigned for two surgery. Primary surgery was performed on the right maxilla and after 30 days, secondary surgery was performed on the left maxilla. In primary surgery, patients consumedL. Sativasyrup (3 times a day for 72 h) and in secondary surgery, patients consumed placebo syrup (3 times a day for 72 h). Pain intensity was measured at 6, 12, 24, 48, and 72 h after a periodontal flap surgery in both surgeries using the Visual Analogue Scale (VAS). All patients received their routine drugs, including analgesics. The number of analgesics used after surgery was recorded. Statistical analysis of t-test was used to compare the results of the two surgery.ResultsThe results showed that the mean pain based on VAS score at 6, 12, 24, 48 and 72 h after primary periodontal flap surgery was significantly reduced compared to the secondary periodontal flap surgery (p<0.001). The results also showed that the use of analgesics after 72 h of surgery was significantly reduced in the primary periodontal flap surgery compared to the secondary periodontal flap surgery (p<0.001).ConclusionsAccording to the results of this study,L.Sativasyrup can be effective as adjuvant therapy in reducing pain after periodontal flap surgery.
Craniosynostosis in a patient with Fanconi–Bickel syndrome: a case report
Authors: Demczko Matthew M. , Liu Tullis T. , Napoli Joseph A. 
Published: July 2022

Abstract

Objectives:
Craniosynostosis may be a rare but severe complication of Fanconi–Bickel syndrome (FBS). Both conditions can be associated with feeding intolerance in young children. Prompt recognition and correction of increased intracranial pressure may lead to improved dietary tolerance in FBS patients and decrease morbidity.

Case presentation
We present the case of a child with genetically confirmed FBS, severe feeding intolerance and evidence of metabolic bone disease. At two years of age, a diagnosis of multi-sutural craniosynostosis with increased intracranial pressure was made. The patient underwent cranial vault expansion using distraction osteogenesis, after which his feeding intolerance completely resolved.

Conclusions
This case highlights the importance of monitoring for secondary craniosynostosis in patients with FBS and frequent emesis. Objective markers of bone health may help identify children at highest risk, though the actual mechanism of development is likely multifactorial. Increased awareness of this potential association should prompt more routine screening and improve outcomes.
The use of neurally-adjusted ventilatory assist (NAVA) for infants with congenital diaphragmatic hernia (CDH)
Authors: Poole Grace , Shetty Sandeep , Greenough Anne 
Published: July 2022

Abstract

Objectives
Newborns with congenital diaphragmatic hernia (CDH) can have complex respiratory problems which are worsened by ventilatory induced lung injury. Neurally adjusted ventilator assist (NAVA) is a potentially promising ventilation mode for this population, as it can result in improved patient-ventilator interactions and provision of adequate gas exchange at lower airway pressures.

Content
A literature review was undertaken to provide an overview of NAVA and examine its role in the management of infants with CDH.

Summary
NAVA in neonates has been used in CDH infants who were stable on ventilatory support or being weaned from mechanical ventilation and was associated with a reduction in the level of respiratory support.

Outlook
There is, however, limited evidence regarding the efficacy of NAVA in infants with CDH, with only short-term benefits being investigated. A prospective, multicentre study with long term follow-up is required to appropriately assess NAVA in this population.