bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of Australian clinical quality registries in pregnancy care: A scoping review
Authors: Campion Tarun Sai David , Daly J. Oliver , Wake Melissa , Ahern Susannah , Said Joanne M. 
Published: May 2022

BackgroundPregnancy represents a time of increased morbidity and mortality for women and their infants. Clinical quality registries (CQRs) collect, analyse and report key healthcare quality indicators for patient cohorts to improve patient care. There are limited data regarding existing CQRs in pregnancy. This scoping review aimed to: (1) identify Australian CQRs specific to pregnancy care and describe their general characteristics; and (2) outline their aims and measured outcomesMethodsThe scoping review was undertaken according to Joanna Briggs Institute guidelines. CQRs were identified using a systematic approach from publications (Ovid MEDLINE, PubMed, Google Scholar), peer consultation, the Australian register of clinical registries and web searches. Details surrounding general characteristics, aims and outcomes were collated.ResultsWe identified two primary sources of information about pregnancy care. (1) Six CQRs are specific to pregnancy (Australia and New Zealand twin‐twin transfusion syndrome registry, Australian Pregnancy Register for women with epilepsy and those taking anti‐epileptic drugs, National Register of Antipsychotic Medication in Pregnancy, Australasian Maternity Outcomes Surveillance System, Neonatal Alloimmune Thrombocytopaenia Registry and the Diabetes in Pregnancy clinical register). (2) Fourteen observational cohort studies were facilitated by non‐pregnancy‐specific CQRs where a subsection of patients underwent pregnancy.ConclusionsAustralian CQRs currently report varied information regarding some selected conditions during pregnancy and offer therapeutic and epidemiological insight into their care. Further research into their effectiveness is warranted. We note the lack of a CQR spanning the common problems of pregnancy in general, where significant health, service and economic gains are possible.
Letter: paying attention to the comorbidities or extraintestinal complications in patients with inflammatory bowel disease during the COVID‐19 pandemic
Authors: Yuan Wen‐Qiang , Li Fei , Yang Liu‐Chan , Yang Zai‐Li , Cui De‐Jun 
Published: May 2022

LINKED CONTENTThis article is linked to Hadi et al papers. To view these articles, visit https://doi.org/10.1111/apt.16730.
Editorial: liver and kidney injury from remdesivir—an issue not as much as its purpose. Authors' reply
Authors: Wong Carlos K. H. , Au Ivan C. H. , Cheng Wing Yiu , Man Kenneth K. C. , Lau Kristy T. K. , Mak Lung Yi , Lui Sing Leung , Chung Matthew S. H. , Xiong Xi , Lau Eric H. Y. , Cowling Benjamin J. 
Published: May 2022

LINKED CONTENTThis article is linked to Wong et al papers. To view these articles, visit https://doi.org/10.1111/apt.16894 and https://doi.org/10.1111/apt.16921
Reaching people receiving opioid agonist therapy at community pharmacies with hepatitis C virus: an international randomised controlled trial
Authors: Byrne Christopher J. , Radley Andrew , Inglis Sarah K. , Beer Lewis , Palmer Nicki , Duc Pham Minh , Allardice Kate , Wang Huan , Robinson Emma , Hermansson Monika , Semizarov Dimitri , Healy Brendan , Doyle Joseph S. , Dillon John F. 
Published: May 2022

SummaryBackgroundConventional healthcare models struggle to engage those at risk of hepatitis C virus (HCV) infection. This international study evaluated point‐of‐care (PoC) HCV RNA diagnostic outreach and direct‐acting antiviral (DAA) treatment for individuals receiving opioid agonist therapy (OAT) in community pharmacies.AimsWe assessed the effectiveness of a roving nurse‐led pathway offering PoC HCV RNA testing to OAT clients in community pharmacies relative to conventional care.MethodsPharmacies in Scotland, Wales, and Australia were randomised to provide PoC HCV RNA testing or conventional referral. Pharmacists directed OAT clients to on‐site nurses (intervention) or local clinics (control). Infected participants were treated with DAAs, alongside OAT. Primary outcome was the number of participants with sustained virologic response at 12 weeks (SVR) and analysed using mixed effects logistic regression in the intention‐to‐treat (ITT) population.ResultsForty pharmacies were randomised. The ITT population contained 1410 OAT clients. In the conventional arm (n = 648), 62 (10%) agreed to testing, 17 (27%) were tested, 6 (35%) were positive and 5 (83%) initiated treatment. In the intervention arm (n = 762), 148 (19%) agreed to testing, 144 (97%) were tested, 23 (16%) were positive and 22 (96%) initiated treatment. SVR was obtained by 2 (40%; conventional) and 18 (82%; intervention). Intervention arm participants had higher odds of testing, OR 16.95 (7.07–40.64, p < 0.001); treatment, OR 4.29 (1.43–12.92, p = 0.010); and SVR, OR 8.64 (1.82–40.91, p = 0.007).ConclusionsNurse‐led PoC diagnosis in pharmacies made HCV care more accessible for OAT clients relative to conventional care. However, strategies to improve testing uptake are required. Trial registration: NCT03935906.
Effect of timing of paddock allocation in tropical grass on performance, nitrogen excretion, and enteric methane emissions from dairy cows
Authors: Batalha Camila Delveaux Araujo , Franklin de Souza Congio Guilhermo , Chiavegato Marília Barbosa , Berndt Alexandre , Frighetto Rosa Toyoko Shiraishi , Santos Flávio Augusto Portela , Da Silva Sila Carneiro 
Published: May 2022

AbstractThe objective of this study was to investigate the influence of timing of paddock allocation (AM or PM) in tropical grass on nutritive value of the herbage, dry matter intake (DMI), milk yield and composition, ruminal fermentation, nitrogen excretion, and enteric CH4 emissions of dairy cows. Twenty cows were grouped in pairs and randomly distributed within pair to one of two treatments. PM herbage had greater contents of dry matter (DM), soluble carbohydrates, starch, and nonfibrous carbohydrate to protein ratio and lower contents of neutral detergent fiber and acid detergent fiber. There was no treatment effect on DMI, N excretion, milk yield, and CH4 emissions. However, milk protein and casein yields tended to be greater for PM than AM, while milk urea nitrogen concentration was lower for PM than AM. The increase in nutritive value of the afternoon relative to the morning herbage within the framework of this study was not large enough to increase DMI and milk yield or to decrease CH4 emission intensity by the dairy cows as hypothesized. The findings indicate that PM treatment can be a simple and useful grazing strategy that results in an herbage harvest with greater nutritional value and in lower excretion of urea N into milk.
Comparison of thrombocytopenia between patients with non‐alcoholic fatty liver disease and those with hepatitis C virus‐related chronic liver disease
Authors: Kinoshita Naohiko , Shima Toshihide , Terasaki Kei , Oya Hirohisa , Katayama Takayuki , Matsumoto Junko , Mitsumoto Yasuhide , Mizuno Masayuki , Mizuno Chiemi , Hirohashi Rina , Sakai Kyoko , Okanoue Takeshi 
Published: May 2022

AbstractAimThrombocytopenia is widely recognized as a simple surrogate marker of liver fibrosis in non‐alcoholic fatty liver disease (NAFLD). Thrombocytopenia of NAFLD has not been compared with that of hepatitis C virus‐related chronic liver disease (CLD‐C). Here, we examined whether there is any difference in the platelet counts between patients with NAFLD and CLD‐C and investigated the underlying mechanisms.MethodsA total of 760 biopsy‐confirmed NAFLD and 1171 CLD‐C patients were enrolled. After stratification according to the liver fibrosis stage, platelet counts between NAFLD and CLD‐C patients were compared. The platelet count, spleen size, serum albumin level, serum thrombopoietin level, and immature platelet fraction (IPF) value were also compared after covariate adjustment using propensity score (PS) matching.ResultsThe median platelet counts (×104/μL) of NAFLD and CLD‐C patients were 20.2 and 18.7 (p = 2.4 × 10−5) in F1; 20.0 and 14.5 (p = 2.1 × 10−12) in F2; 16.9 and 12.3 (p = 8.1 × 10−10) in F3; and 11.1 and 8.1 (p = 0.02) in F4, respectively. In the F3 group, NAFLD patients had a significantly higher platelet count and significantly smaller spleen volume than CLD‐C patients. Although the serum thrombopoietin levels were comparable between NAFLD and CLD‐C patients, the IPF value of NAFLD patients was significantly higher than that of CLD‐C patients.ConclusionsNAFLD patients had a significantly higher platelet count than CLD‐C patients following stratification according to the liver fibrosis stage. The milder hypersplenism and higher platelet production in NAFLD than CLD‐C may have contributed to this difference.
The effects of a mobile application for patient participation to improve patient safety
Authors: Lee Nam‐Ju , Ahn Shinae , Lee Miseon 
Published: May 2022

AbstractBackgroundPatient participation in patient safety activities in care processes is a fundamental element of safer care. Patients play an important role in preventing patient safety incidents and improving health outcomes. Therefore, healthcare providers need to develop and provide educational materials and actionable tools for patient participation.ObjectivesThis study aimed to develop a mobile application for health consumers' participation and evaluate the effect of the mobile application on improving health consumers' participation in patient safety.MethodsA quasi‐experimental design was adopted. We developed a mobile application on the basis of a needs assessment, literature review, compilation of patient safety topics, and validity testing of the application. The target population included Korean adults aged between 30 and 65 years who had visited a medical institution more than once within the most recent 6 months. The intervention group received patient participation training by using the mobile application, Application for Patient Participation in Safety Enhancement, for 2 months. The primary outcome variables were patient safety knowledge, self‐efficacy of participation, willingness to participate and experience of patient participation in patient safety activities. End‐user satisfaction was assessed using a questionnaire. To assess participants' experiences with the intervention, qualitative data were collected through a focus group interview and open‐ended responses to an end‐user satisfaction survey.ResultsThe intervention group (n = 60) had significantly higher overall average scores than the control group (n = 37) with regard to patient safety knowledge (p < .001), self‐efficacy of participation (p = .001), willingness to participate (p = .010) and experience of participation (p = .038) in the post‐survey. The total mean end‐user satisfaction score was 3.56 ± 0.60. The participants expressed the realization that patients could play an important role in improving patient safety.ConclusionsThis study demonstrated that educating health consumers through a mobile application with useful information improves patient participation in patient safety activities. Educational materials and patient participation tools could motivate health consumers' health‐related behaviours.Patient or Public ContributionPatients were involved during the programme development and evaluation.
Effects of home‐based telehealth on the physical condition and psychological status of patients with chronic obstructive pulmonary disease: A systematic review and meta‐analysis
Authors: Song Chun‐Yu , Liu Xin , Wang Ya‐Qing , Cao Hui‐Ping , Yang Zhuo , Ma Rui‐Chen , Yin Ying‐Ying , Xie Jiao 
Published: May 2022

AbstractAimsThis systematic review and meta‐analysis aimed to evaluate the effects of home‐based telehealth compared with usual care on six‐minute walking distance (6MWD), health‐related quality of life, anxiety and depression in patients with chronic obstructive pulmonary disease.MethodsWe identified randomized controlled trials through a systematic multidatabase search. Titles and abstracts were assessed for relevance. Two authors independently extracted data and assessed the risk of bias and quality of evidence. Meta‐analyses were conducted using Review Manager and Stata.ResultsWe included 32 randomized controlled trials (n = 5232). Devices used for home‐based telehealth interventions included telephones, videos, and combined devices. The quality of the evidence was downgraded due to high risk of bias, imprecision, and inconsistency. Home‐based telehealth significantly increased 6MWD by 35 m (SD = 30.42) and reduced symptom burden by 3 points (SD = −2.30) on the COPD assessment test compared with usual care. However, no significant differences in anxiety and depression were noted between the home‐based telehealth group and the standard care group. In subgroup analysis, home‐based telehealth significantly improved 6MWD and health status after 6–12 months and >12 months.ConclusionLow quality evidence showed that home‐based telehealth interventions reduce symptom burden and increase walking distance to a clinically meaningful extent in patients with COPD. However, no effects on depression and anxiety were observed.
Social network analysis: Understanding nurses’ advice‐seeking interactions
Authors: Kantek Filiz , Yesilbas Hande , Yildirim Nezaket , Dundar Kavakli Bahar 
Published: May 2022

AbstractAimThis study aimed to determine advice‐seeking interactions of nurses in a private hospital by using social network analysis.DesignThis study was designed as a cross‐sectional descriptive study.MethodsThe study was conducted in a private hospital with 70 nurses. The data were collected with a social network analysis questionnaire. The social network analysis (SNA) focused on certain values such as network density, component, degree centrality, and betweenness centrality. The SNA was carried out using UCINET, and statistical analyses were performed with SPSS version 23.0.ResultsThe network density was reported to be 0.062, and it was composed of three components. It was further noted that nurse Y1 was found to have the highest scores of degree and betweenness centrality. Chi‐Square Automatic Interaction Detector (CHAID) analysis indicated that the most common variables that affected degree centrality score were education, department, and position.ConclusionIt was concluded that social network analysis was a useful instrument to delineate strengths and weaknesses of seeking advice relationships among nurses.Implications for nursing and health policyTop‐ and middle‐level nursing managers occupy a significant position in advice‐seeking networks. Nursing managers with higher education degrees will absolutely improve advice‐seeking networks.
In situ separation and characterization of britholite crystals in RE‐bearing slag via supergravity
Authors: Lan Xi , Gao Jintao , Xu Huanhuan , Guo Zhancheng 
Published: May 2022

AbstractBayan Obo ore has abundant rare earth (RE) reserves, and RE elements (REEs) are mainly transferred into the RE‐bearing slag. However, the utilization of RE‐bearing slag is greatly limited due to the serious lack and ambiguity of RE crystals. In this study, in situ separation of RE crystals from RE‐bearing slag via supergravity was developed, and the high‐purity crystals of britholite with various REEs contents were selectively separated from the CaO–SiO2–CaF2–P2O5–Ce2O3 system with a high REEs recovery ratio of 95.58%–98.65%. On this basis, the chemical formula, the crystal structure, and the formation mechanism of britholite were characterized from the high‐purity crystals through a combination of the Rietveld refinement and DFT calculation. It was found that the britholite was verified to be evolved from Ca5(PO4)3F, there would be an SiO44− instead of a PO43− when a Ce3+ replaced a Ca2+, the chemical formula changed from Ca5(PO4)3F to Ca4.377Ce0.623Si0.6P2.4O12F, Ca3.956Ce1.044Si1.01P1.99O12F, and Ca3.176Ce1.824Si1.93P1.07O12F with the increase of REEs content, and the substitution range of REEs was between 0 and 2. This study supplements some necessary basic data of RE crystals, which provides the theoretical reference for efficient recovery of RE resources and sustainable utilization of RE‐bearing slag.
Ultralow‐threshold wideband‐tunable single‐mode ultraviolet lasing from lanthanide‐doped upconversion nanomaterials
Authors: Jin Limin , Yang Xiaoli , Yu Siufung , Zheng Puran , Chen Xian , Xiao Shumin , Song Qinghai 
Published: May 2022

AbstractUltraviolet (UV) lasers with dynamic wavelength‐tunability and high monochromaticity are crucial in a multitude of practical applications yet still remarkable challenges. Here, we show wide wavelength‐tuning of single‐mode UV lasing based on lanthanide‐doped upconversion nanoparticles (UCNPs). The rationally designed Yb3+/Er3+/Tm3+/Gd3+/Ce3+ co‐doped multilayer UCNPs, which exhibits a broad gain spectrum with the full width of half maximum of around 57 nm in the UV regime, are developed. More importantly, by taking advantages of a diffraction grating as the tuning component, stable single‐mode emission can be achieved in the UCNPs‐based external‐cavity‐extended Fabry–Pérot laser at room temperature. Specifically, the lasing threshold is around 137 µJ cm–2, which is two orders of magnitude lower than that in the previously reported articles. Precise wavelength‐tuning from 310 to 363 nm can be realized by adjusting the Littrow angle. This achievement highlights a portable alternative to continuously wideband‐tunable UV lasers and opens up new opportunities for constructing compact solid‐state UV photon sources.
Putative therapeutic impacts of cardiac CTRP9 in ischaemia/reperfusion injury
Authors: Sadat‐Ebrahimi Seyyed‐Reza , Amini Hassan , Rahbarghazi Reza , Habibollahi Paria , Ghaderi Shahrouz , Rajabi Hadi , Rezabakhsh Aysa 
Published: May 2022

AbstractRecently, cytokines belonging to C1q/tumour necrosis factor‐related proteins (CTRPs) superfamily have attracted increasing attention due to multiple metabolic functions and desirable anti‐inflammatory effects. These various molecular effectors exhibit key roles upon the onset of cardiovascular diseases, making them novel adipo/cardiokines. This review article aimed to highlight recent findings correlated with therapeutic effects and additional mechanisms specific to the CTRP9, particularly in cardiac ischaemia/reperfusion injury (IRI). Besides, the network of the CTPR9 signalling pathway and its possible relationship with IRI were discussed. Together, the discovery of all involved underlying mechanisms could shed light to alleviate the pathological sequelae after the occurrence of IRI.
Historical Perspectives on Score Comparability Issues Raised by Innovations in Testing
Authors: Baldwin Peter , Clauser Brian E. 
Published: May 2022

AbstractWhile score comparability across test forms typically relies on common (or randomly equivalent) examinees or items, innovations in item formats, test delivery, and efforts to extend the range of score interpretation may require a special data collection before examinees or items can be used in this way—or may be incompatible with common examinee or item designs altogether. When comparisons are necessary under these nonroutine conditions, forms still must be connected bysomethingand this article focuses on these form‐invariant connectivesomethings. A conceptual framework for thinking about the problem of score comparability in this way is given followed by a description of three classes of connectives. Examples from the history of innovations in testing are given for each class.
Gill area explains deviations from body size–metabolic rate relationship in teleost fishes
Authors: Kuparinen Anna , Gielewski Darby , Hutchings Jeffrey A. 
Published: May 2022

AbstractWhether gill area constrains fish metabolism through oxygen limitation is a debated topic. Here, the authors provide insights into this question by analysing mass‐specific metabolic rates across 44 teleost fishes extracted from FishBase. They explore whether species deviations from metabolic rates predicted by body mass can be explained by species gill area. They show that the gill area explains c. 26%–28% of species‐level deviations from mass‐specific metabolic rates. Their findings suggest that gill area might indeed be one of the factors limiting metabolic rate in fishes.
A matter of timing: System requirements for repair and their temporal dimensions
Authors: Russell Jennifer D. , Svensson‐Hoglund Sahra , Richter Jessika Luth , Dalhammar Carl , Milios Leonidas 
Published: May 2022

AbstractResearch into repair within the circular economy (CE) typically focuses on technical aspects of design, policy, and markets, and often assumes simplified conditions for the user/owner and the product system to explain the barriers to scaling repair activities. However, factors occurring at pre‐use stages of the product's life cycle can significantly influence whether, and to what extent, repair is viable or possible, that is, warranty duration, after‐sale service provision, and access to necessities. The passing of time can directly and indirectly affect the ability, difficulty, and thus, the likelihood of repair activities being performed at each stage of the product's life cycle. Drawing from the literature and applying inductive systems‐thinking tools, we propose a framework for considering the “System of Repairability.” We delineate how the passing of time (temporal dimensions) affects one's ‘‘ability to repair,’’ as a product progresses through different life cycle phases (i.e., breakdown vs. repair vs. disposal), and the point(s) at which the repair is considered or attempted (i.e., year of usage). By integrating life cycle and temporal (time‐based) dimensions into a broad System of Repairability framework, we clarify relevant interconnections, iterations, sequences, and timing of decision points, stakeholders, and necessary conditions to facilitate an outcome of successful repair at the individual level, and thus intervention strategies for scaling repair within CE. We discuss how a policy mix can address the life cycle of products and the repair system more holistically. We conclude with a future outlook on how temporal dimensions can inform policy strategies and future research.
F‐35 Crisis: Will Turkish‐US Defense Cooperation Continue?
Authors: Özgen Cenk , Yılmaz Eren Alper , Örmeci Ozan 
Published: May 2022

AbstractAlthough Turkish‐American defense cooperation goes back many years, recent steps taken by Turkey have led to a serious crisis. Following the decision to withdraw Patriot air‐defense batteries deployed in the south of Turkey by Germany and the United States after 2015, Ankara turned to Russia for the S‐400 missile‐defense system, citing national security. Turkey was then excluded from the F‐35 program, in which it had been involved for years. Moreover, it was sanctioned by the White House. In this context, the background of Turkish‐American defense cooperation, the F‐35 program, the removal of Turkey from the program after the S‐400 purchase decision, and the subsequent exposure to sanctions are discussed, and the sanctions analyzed for compliance with international law. It is emphasized that the revival of close defense cooperation between Turkey and the United States is essential for the future of the relationship, and that the parties should find an intermediate formula for compromise.