bluuebunny/crossref_metadata_2025_split huggingface dataset:
ACIDENTES E PLANTAS HOSPEDEIRAS ASSOCIADAS A LAGARTAS URTICANTES
Authors: Alberti Andressa , Mendes Ellen Jaqueline , Bollis Eliane , Lazxzari Konflanz Alexandre , Sabedot Bordin Sandra Mara , Lutinski Junir Antonio 
Published: November 2022

Introdução: Ambientes urbanos como áreas verdes, praças, parques e escolas estão se tornando cada vez mais propícios ao aparecimento de animais peçonhentos, dentre eles as lagartas urticantes. Acidentes com algumas lagartas urticantes podem ser graves, podendo leva ao óbito, como no caso do gênero Lonomia. Objetivo: descrever o perfil epidemiológico dos acidentes envolvendo lagartas urticantes no município de Chapecó, Santa Catarina e identificar espécies vegetais hospedeiras destas lagartas. Metodologia: Foram coletados os dados epidemiológicos dos acidentes com lagartas urticantes registrados no período entre 2016 e 2017. Os dados foram obtidos junto ao Sistema de Informação de Agravos de Notificação (SINAN). Foram analisadas as variáveis sexo, idade, parte do corpo acometida, os meses que houve as notificações, a ocupação dos indivíduos que tiveram contato com a lagarta, local em que residem, escolaridade e a espécie da lagarta envolvida. Ainda, foram identificados os espécimes coletados pelo setor de Vigilância em Saúde Ambiental, bem como foram identificadas as plantas hospedeiras em que foram encontrados. Resultados: Foram registrados 377 acidentes envolvendo majoritariamente o sexo feminino e a faixa etária entre 20 a 49 anos. As partes do corpo mais acometidas foram o pé (17,0%), mão (12,9%) e cabeça (11,4%). Foram identificadas seis espécies de plantas associadas à ocorrência de lagartas urticantes Conclusões: O estudo contribui com informações epidemiológicas sobre os acidentes causados por lepidópteros em um município de grande porte. Ressalta-se, a importância de ampliar as pesquisas em relação às plantas hospedeiras e a divulgação dos resultados visando a prevenção de acidentes.
Protease Inhibitors (PIs): Candidate Molecules for Crop Protection
Formulations against Necrotrophs
Authors: Nair Aswati R. , Pillai Padmesh , Raj Sharmila 
Published: November 2022

Abstract:
Necrotrophic phytopathogens pose a serious challenge to the productivity of several crops
causing seedling damage, pre- and post-emergence damping-off and root rot thus reducing plant
growth and yield. They are known to gain nutrition by secreting a diverse array of hydrolytic enzymes
and thereby causing extensive host plant tissue maceration. Amongst the diverse hydrolases, proteases
play a pivotal role in the necrotrophic mode of nutrients and thereby in determining pathogenic
virulence. Host plants often counteract the necrotrophic proteolysis events by proteins (peptides),
particularly through protease inhibitors (PIs). PIs play an important role in host innate immunity
function by functioning as anti-metabolic proteins inhibiting the activity of phytopathogenic secretory
proteases. Their abundance in plant storage organs explains their anti-nutritional interaction which
stalls pathogenic invasion. PIs, therefore, constitute potential candidates that can be deployed as
effective antimicrobials in agriculture, particularly against necrotrophic soil-borne pathogens. The
present review traces the progress made in the identification of PIs from plants, and their inhibitory
potential against necrotrophic phytopathogens and explores prospects of utilizing these molecules as
effective anti-necrotrophic formulations for disease management.
Eco-friendly, Fact and Green Synthesis of Methanobenzo[d]naphtho[1,2-
g][1,3]Oxazocines using 1-Butyl-3-methylimidazolium Hydroxide under
Solvent-free Ball Milling
Authors: Pouramiri Behjat 
Published: November 2022

Abstract:
A green, solvent-free, and efficient strategy for the assembly of methanobenzo[
d]naphtho[1,2-g][1,3]oxazocine heterocycles using 1‑butyl‑3‑methylimidazolium hydroxide
([bmim]OH) ionic liquid under ball-milling solvent-free condition has been developed. For this purpose,
the synthesis of methanobenzo[d]naphtho[1,2-g][1,3]oxazocine derivatives was carried out in a single
step and one-pot reaction using 2-naphthol and quinolinium salts with the catalyst, 1‑butyl‑3‑
methylimidazolium hydroxide ([bmim]OH), at room temperature. This protocol's specific advantages
are environmentally benign media, high yield, easy purification and short experimental time.
In silico Identification of Putative Drug Targets in Mycobacterium ulcerans
Virulence Proteins
Authors: Mohinani Taruna , Saxena Aditya , Singh Shoor Vir , Pathak Amita 
Published: November 2022

Background:
Buruli ulcer (BU), caused by Mycobacterium ulcerans is a neglected tropical
disease characterized by necrotic skin lesions. Antibiotic therapy and excision of the lesions are the treatments
for this chronic disease. During the management of the disease, the emergence of drug resistance in
these bacilli is a major challenge. Therefore, there is a need to identify new drug targets against this important
pathogen.

Objective:
The study aimed to investigate novel drug targets exploring virulence factors of M. ulcerans by
in silico analysis.

Methods:
Virulence proteins encoded by the chromosome of Mycobacterium ulcerans strain Agy99 were
retrieved and analyzed for their cellular localization, human non-homology and essentiality. Further, proteins
were analyzed for their physio-chemical characterization, drug resistance analysis, protein interaction
analysis, metabolic pathway prediction, and druggability prediction by various databases and online
software to find their suitability as drug targets. The structure of the predicted drug targets was also modeled
and validated. Among three predicted drug targets, MUL_4536 was subjected to molecular docking
with some known inhibitor compounds also. Receptor-ligand complex with the highest binding energy
was selected for molecular dynamic (MD) simulation to determine the structural stability of the complex.

Results:
Three virulence proteins MUL_4536, MUL_3640, and MUL_2329 encoding enzymes iso-citrate
lyase, lysine-N-oxygenase, pup-protein ligase, respectively were predicted as a drug target against M.
ulcerans. Isocitrate lyase has been identified as a potential drug target in many other mycobacterial and
non-mycobacterial diseases. Lysine-N-oxygenase is the enzyme of mycobactin biosynthesis pathway and
pup-protein ligase is associated with the pup-proteasome system. Proteins of these pathways have been
studied as attractive drug targets in previous research works, which further support our predictions.

Conclusion:
Our computational analysis predicted new drug targets, which could be used to design drugs
against M. ulcerans. However, these predicted proteins require further experimental validation for their
potential use as drug targets.
Adsorption of Chromium (VI) from Aqueous Solution Using Nano TiO2
Doped Strong Base Anion Exchange Resin
Authors: Koujalagi Prasanna S. , Revankar Harish N. , Gurjar Vijayendra R. , Kulkarni Raviraj M. 
Published: November 2022

Background:
The evolution of environmentally-safe methods for treating hazardous chemicals
in wastewater, particularly urban and industrial wastewater, has increased interest over recent
years. The chromium-containing wastewater is produced by industries from steel, metallurgical, electroplating,
chemical, refractory, leather tanning, dye manufacturing, mining, cementing, textiles, etc.
Consequently, advanced techniques are essential for treating chromium-polluted water.

Objective:
The prime objective of this effort was to assess the adsorption performance of nanoTiO2
(nanoparticles of average crystallite size 19.15 nm) doped strong base anion exchange resin (TDTulsion)
for Cr(VI)to that of the host Tulsion A-62 (MP).

Methods:
The tests were carried out in batches in the temperature-controlled water bath shaking unit,
with 30 ml of the aqueous solution containing Cr(VI) and a certain amount of resin being stirred for 6
hours at 303 K. Using a standard diphenylcarbazide (DPC) procedure at 540 nm, the solution was
spectrophotometrically analyzed for Cr(VI).

Results:
The majority of the Cr(VI) ions are adsorbed by the anion exchange resins Tulsion A-
62(MP), and TD-Tulsion is in the pH range of 4.0 to 5.0. The maximal sorption capacity of Cr (VI)
was established to be 181.5 and 204.8 mg/g for Tulsion A-62(MP) and TD-Tulsion, respectively.

Conclusion:
The TD-Tulsion has a substantially better adsorption capacity than Tulsion A-62(MP) under
similar conditions. The outcomes show that modifying anion-exchange resin with nano titanium dioxide
improves adsorption performance in Cr(VI) removal from drinking water and contaminated water.
Can the Therapeutic Spectrum of Probiotics be Extended: Exploring
Potential of Gut Microbiome
Authors: Rastogi Sonakshi , Singh Aditi , Nandi Abhishek , Gupta Akanksha , Agarwal Jyotsna , Kostova Irena 
Published: November 2022

Abstract:
Natural therapeutic microorganisms provide a potent alternative healthcare
treatment nowadays, with the potential to prevent several human diseases. These
health-boosting living organisms, probiotics mostly belong to Gram-positive bacteria
such as Lactobacillus, Bifidobacterium, Streptococcus, Saccharomyces, Bacillus and
Enterococcus. Initiated almost a century ago, the probiotic application has come a long
way. The present review is focused on the potential therapeutic role of probiotics in
ameliorating multiple infections, such as upper respiratory tract infections and viral respiratory
infections, including COVID-19; liver diseases and hepatic encephalopathy;
neurological and psychiatric disorders; autoimmune diseases, particularly rheumatoid
arthritis, systemic lupus erythematosus and multiple sclerosis. Apart from these, the
therapeutic exacerbations of probiotics in urinary tract infections have been extremely
promising, and several approaches are reviewed and presented here. We also present upcoming
and new thrust areas where probiotic therapeutic interventions are showing
promising results, like faecal microbial transplant and vaginal microbial transplant.
Fabrication and Optimisation of Cashew Nut Butter from Different Vegetable
Oils
Authors: Mohammed Nameer Khairullah , Badrol Hisam Nurul Afikah , Meor Hussin Anis Shobirin 
Published: November 2022

Background:
One of the significant problems with peanut butter is oil separation
when the product is opened after some time. The selection of vegetable oil, which acts as a stabiliser,
plays a significant role in nut butter's textural and sensory quality.

Objective:
This study aimed to optimise the formulation of cashew nut butter using response surface
methodology (RSM). Four different vegetable oils, namely olive oil, virgin coconut oil,
soybean oil and palm oil, were used to select efficient vegetable oil based on its effect on the
physicochemical characteristics and sensory evaluation of cashew nut butter.

Methods:
Thirteen formulations of cashew nut butter from RSM were produced to determine the
optimum amount of selected oil (olive oil) and honey.

Results:
Cashew nut butter stabilised with olive oil showed the best and similar values to commercial
peanut butter with the lowest oil separation 3.91% and lower values of texture data of
firmness (85.8 g), shear work (87.8 g.sec), stickiness (-27.44 g) and work of adhesion (-36.07
g.sec). The recommended volumes of olive oil and honey for cashew nut butter production were
1.29% and 6.16%, respectively. Consumers favor cashew nut butter, according to sensory analysis'
overall acceptance. In terms of nutritional quality, cashew nut butter contains a high amount
of fat (47.25%), followed by carbohydrates (24.51%) and protein (16.4%).

Conclusion:
The type of oil showed significant effects on the stability and spreadability of the
produced cashew nut butter.
Ide-praksis-oversættelsesmodellen
Authors: Scheuer John Damm 
Published: November 2022

Denne artikel tager udgangspunkt i, at løsning af klima- og CO2-udledningskrisen kræver oversættelse og samskabelse af nye socio-tekniske løsninger i offentlig-private inno-vationsnetværk- og grupper. Den redegør for ide-praksis-oversættelsesmodellens socio-tekniske forståelse af sådanne samskabelses-, design- og oversættelsesprocesser og for, hvad de ledelsesmæssige konsekvenser af den er i den forbindelse. Endelig diskuteres, hvordan processen vil kunne accelereres på den baggrund.
(Bemærk: Artiklen genudgives i dette nummer, fordi artiklens figur 1 ikke fremgik af den oprindelige artikel. Den oprindelige artikel findes i Årg 37, nr. 3 (2022))
Should patients with Parkinson’s disease only visit a neurologist’s office? - a narrative review of neuropsychiatric disorders among people with Parkinson’s disease
Authors: Szarpak Julita , Drożak Paulina , Piwoński Michał , Wróblewski Hubert , Morylowska-Topolska Justyna 
Published: November 2022

Abstract

Introduction: Parkinson’s disease is a neurodegenerative disease that is often accompanied by disorders such as depression, psychotic disorders, cognitive disorders, anxiety disorders, sleep disorders, impulse control disorders. The aim of the study was to review the literature and present the characteristics of neuropsychiatric disorders occurring in people suffering from Parkinson’s disease, with the specification of the above-mentioned disorders.

Material and method: The literature available on the PubMed platform from 1986 to 2022 was reviewed using the following keywords: Parkinson’s disease, depression, anxiety disorders, psychotic disorders, sleep disorders, cognitive disorders, impulse control disorders. Original studies, reviews, meta-analyzes and internet sources were analyzed.

Results: The above-mentioned neuropsychiatric disorders appear with different frequency among people suffering from Parkinson’s disease and occur at different times of its duration or even precede its onset for many years. The non-motor symptoms in the form of depressed mood, energy loss or changes in the rhythm of the day may result in a delay of appropriate therapy and thus in complications. Neuropathological changes in the course of Parkinson’s disease as well as dopaminergic drugs used in its therapy influence the development of neuropsychiatric disorders.

Conclusions: In order to avoid misdiagnosis, practitioners should use, e.g. scales intended for patients with Parkinson’s disease. To prevent the consequences of the aforementioned disease entities, methods of early diagnosis, determination of risk factors and standardization of the treatment process must be determined. Consistent care for patients with Parkinson’s disease is significant, not only in the neurological field, but also in the psychiatric one.
Monitoring population change using ’citizen science’ data: case study of the Hungarian White Stork(Ciconia ciconia)population between 1999 and 2021
Authors: Lovászi Péter , Nagy Károly , Görögh Zoltán , Szép Tibor 
Published: November 2022

AbstractIn Hungary, changes in the White Stork population are monitored using two methods that involve a large number of volunteers: nest surveys since 1941, and since 1999 within the framework of the Common Bird Monitoring Scheme (MMM) programme. In our article, we briefly present the results of the nest survey data between 1999 and 2021, the population trend calculated on the basis of them, and the comparison of the latter with the trends shown by the MMM programme, which – among other species – counts all stork individuals on 2.5×2.5 km sample areas. Both sets of data show a decreasing trend, but there is a significant difference between them, which may be partly due to the inaccuracies of the nest database, considering the fact that the MMM also counts non-breeding adult and immature individuals. However, both methods have the characteristics that make them suitable for monitoring population trends.
Development of Massive Online Open Course ‘Energy Transition and Climate Change’
Authors: Cervinska Elina , Blumberga Andra , Kalnbaļķite Antra , Pubule Jelena 
Published: November 2022

Abstract
This study focuses on designing a massive open online course (MOOC) to enhance students learning about the energy transition process and its connection to climate change in theory and complex dynamic systems. The course ‘Energy transition and climate change’ covers one of the United Nations’ ‘Sustainable development goals’ and is one of twelve MOOCs that will enable a comprehensive education in system thinking and its applications. It shows how system thinking methods and tools can be applied to tackle current and future energy and climate problems. The goal of the MOOC is to introduce users to the internal dynamics of modern energy systems and energy transition toward CO2-neutral energy systems. The target audience of the course is students who study Environmental Engineering, Energy, Systems, or similar program and anyone else interested in insights into the topic. The course builds on previous energy supply and demand models by updating and adapting them to the existing situation. MOOC is designed by the Competency-Based Education (CBE) approach, and a literature review is used in the study to cover theoretical parts of the course. Technology Readiness Level (TRL) methodology describes the main steps of the course model development progress, and testing of MOOCs pilot version on five students is included in the final stage of the study.
PROCEDIMIENTO ABREVIADO Y LA VERDAD
Authors: Ceballos Díaz María Elisa Matilde 
Published: November 2022

El esclarecimiento de los hechos es uno de los fines del sistema penal acusatorio en México. El procedimiento abreviado es una forma de terminación anticipada del proceso, en el cual se debe de priorizar la aplicación de los derechos humanos, y donde el imputado y el Ministerio Publico deben de reunir requisitos de procedibilidad, haciendo que sea controversial, ya que se logra previo acuerdo de la defensa y la fiscalía, para que el imputado obtenga un beneficio; por lo que se analizará si a través de este proceso especial se logra esclarecer los hechos delictivos (verdad), con el apoyo de la Constitución de México, en Código Nacional de Procedimientos Penales, sentencias de amparo en revisión, Jurisprudencias, así como doctrina; se explicara el actuar del juez en el proceso penal, como la relación entre el procedimiento abreviado y la verdad. Concluyendo que es una verdad procesal, atendiendo a intereses de las partes, al material probatorio y la valoración del mismo.
In Conversation with: JCMS Editors Past and Present: Maxine David speaks to Simon Bulmer and Toni Haastrup
Authors: UACES  
Published: November 2022

Toni Haastrup (University of Kent) and Simon Bulmer (University of Sheffield) speak to Maxine David (University of Leiden) about the development and future of the Journal of Common Market Studies (JCMS).
The recording of this video was supported by the Erasmus+ Programme of the European Union. The video reflects the views only of the speaker(s). The Commission and UACES cannot be held responsible for any use which may be made of the information contained therein.
In Conversation with: UACES Student Forum Chairs: Simon Usherwood speaks to Viviane Gravey, Elizabeth Monaghan, Miguel Otero-Iglesias and Anna Wambach
Authors: UACES  
Published: November 2022

Viviane Gravey (Queen's University Belfast), Elizabeth Monaghan (University of Hull), Miguel Otero-Iglesias (Real Instituto Elcano), Simon Usherwood (University of Surrey) and Anna Wambach (Newcastle University) share their experiences as UACES Student Forum* Chairs and discuss the development of postgraduate research in European Studies, and ongoing challenges and opportunities.
*The Student Forum is now the UACES Graduate Forum (as of 13 February 2018)
The recording of this video was supported by the Erasmus+ Programme of the European Union. The video reflects the views only of the speaker(s). The Commission and UACES cannot be held responsible for any use which may be made of the information contained therein.
Events of the Russian Civil War in Abkhazia 1918–1921 in the Manuscript Sources of the Estonians from Abkhazia
Authors: Jürgenson Aivar 
Published: November 2022

Abstract
A number of Estonian settlements were formed in Abkhazia in the 1880s. This article uses archival sources, written memoirs, diaries and secondary literature to focus on the experiences of Estonians in Abkhazia during the Russian Civil War until the establishment of Soviet power in 1921. The article discusses what role the proclamation of the Republic of Estonia played for the settlers, and what the change of status from an internal migrant to an emigrant meant for the Estonian community in Abkhazia, but also the political opportunities that the establishment of Estonia as an independent republic brought to compatriots living in the diaspora.
Modernising Security: Vernacular (In)securities in the Public Space of Tbilisi after the Rose Revolution
Authors: Khomeriki Tinatin 
Published: November 2022

Abstract
This article explores the perceptions of personal (in)security in the public space of Tbilisi, Georgia following the Rose Revolution in 2003. Based on the concept of vernacular security, I suggest a bottom-up approach to the subject, focusing on its culturally and socially specific character and observing the production of the discourses of (in)security at the intersecting notions of modernisation/backwardness, formality/informality, criminality/lawfulness, and the West/Russia, reflecting post-revolutionary political, social, and cultural transformations. While the government of the Rose Revolution introduced full-scale reforms formalising security in Georgia, the article reveals that citizens’ perceptions of personal (in)security in the public space are often ambiguous and even self-contradicting, as they waver between the notions of formality and informality, often interpreting the same phenomenon as a source of both their security and insecurity.
Reconstructing a National Hero in the Post-colonial Memory Politics of Abkhazia: Debates over Kelesh Bey Shervashidze
Authors: Epadze Ketevan 
Published: November 2022

Abstract
This article analyzes the reconstruction of the image of Prince Kelesh Bey Shervashidze (b. 1747) in the memory politics of Abkhazia through the prism of cultural resistance, from the perestroika period up to the present day. It argues that Abkhaz politicians use a dual approach to constructing the figure of Kelesh Bey. On the one hand, an anti-colonial narrative of the prince in opposition to the Russian and Soviet colonial system is created, and on the other hand, a more traditional colonial narrative aligned with Russia’s patronage of Abkhazia’s unrecognised statehood is also encouraged. However, the controversy over these discourses is formal in nature. The only real purpose of reviving the Russian and Soviet readings of Kelesh Bey is to hide Abkhaz cultural resistance from Russia, owing to the latter’s own dualistic status as embodying both Abkhazia’s former imperial center and its modern patron.