bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Short-Term Supplementation with Anabolic Steroid Drug Oxymetholone And /Or Creatine Widely Used In Ksa on Some Fertility Biomarkers in Albino Rats
Authors: Sarah T Batais  , Manal Ea Elhalwagy  , Najla O Ayaz  
Published: June 2022

Abuse supplement is becoming a public health problem due to the adverse effects on health and semen quality in Saudi Arabia for the last few years. The present work is aimed to investigates the effect of individual supplementation with oxymetholone as Anabolic Androgenic Steroids (AAS) or creatine protein are the most common nutritional supplement use in the KSA and their mixture on some fertility biomarkers, oxidant-antioxidant activities as well as tissues structure of testis of albino rats. Forty adult male albino rats weighing around 150-200 g were classified into four groups of 10 rats each. Group I: control untreated group. Group II: treated with oxymetholone (150 mg/day). Group III: treated with creatine protein (20 mg/day). Group IV: treated with Oxymetholone (150 mg/day) and creatine protein (20 mg /day) simultaneously. All animals were given orally for 30 days. Individual supplementation with each of oxymetholone or creatine induced significant upregulation in oxidative stress biomarkers Malondialdehyde (MDA), Protein Carbonyls (PC), 8-Hydroxy Guanosine (8OHG). In addition, it also significantly reduced the antioxidants activities Total Antioxidant Capacity (TAC), Catalase (CAT), Superoxide Dismutase (SOD). Remarkable reduction in each of testosterone hormone, luteinizing hormone, sperm counts, and motility was pronounced in oxymetholone treated group than creatine group. The potentiality of oxymetholone was obvious in the mixture treated group. Changes in testis structure architecture follow the same previous trend that confirmed the clinical results. In conclusion; AAS and proteins should be used under supervision of special physicians because it will be very harmful for the reproductive life of users.
Afbouwen van antidepressiva
Authors: Brouwer Sander 
Published: June 2022

Er is veel duidelijk over het opbouwen van antidepressiva, maar die
kennis ontbreekt nog al eens bij het afbouwen. Het afbouwen van
antidepressiva is daarnaast ook niet altijd even eenvoudig voor
patiënten die opzien tegen het afbouwen, bij wie een eerdere poging niet
is gelukt of bij wie angst bestaat dat oorspronkelijke klachten
terugkomen. Volgens de huidige behandelrichtlijnen moet het gebruik van
antidepressiva worden voortgezet tot minstens 6 maanden na remissie van
een eerste depressieve episode. Na deze periode is het echter niet
duidelijk of, wanneer en bij wie stopzetting van antidepressiva
effectief is. In dit artikel staat het langzaam en lager afbouwen van
antidepressiva centraal, maar wordt ook aandacht besteed aan langdurig
gebruik van en het (vroegtijdig) stoppen met antidepressiva.
The Art of Government in Maria Louise's Duchy of Parma (1814–1847): Some Insight into Accounting Disclosure Practices
Authors: Balluchi Federica , Furlotti Katia 
Published: June 2022

ABSTRACT
The aim of this paper is to investigate the administration of the Duchy of Parma under Maria Louise and analyze, based on Foucault's concept of governmentality, the development of accounting documents and rules, providing insights into how accounting may have facilitated the rationalities of government in a critical period for public, administrative, and financial organizations due to the new administration enforced in Parma by Duchess Maria Louise after the period of French occupation. The research considers primary sources, such as the Comprehensive Framework of Parma State Laws (regarding accounting laws) and documentation in the Parma State Archive (regarding accounting reports), as well as secondary sources to form a detailed picture of the duchy's income and expenditure in the period.
The Essential Role of Accounting Information in the Capital Markets: Updating Seminal Research Results with Current Evidence
Authors: Nichols D. Craig , Wahlen James M. 
Published: June 2022

SYNOPSIS
An extensive literature of empirical research over the past 50+ years provides important insights into the role of accounting information in the equity capital markets. But how has the role of accounting information changed, given advancements in the dissemination and processing of accounting information, as well as changes in corporate governance, securities regulations, and trading? In this paper, we use recent data to examine whether seminal findings from prior studies in the following three major areas of research still hold: the earnings-returns relation, earnings management, and market efficiency. We also introduce some new findings that were not in the original studies. We use a framework that maps firms’ business activities into share prices and provide straightforward descriptions of the research methodologies, empirical findings, and important implications from the evidence to benefit accounting students, instructors, practitioners, and others who may not yet have been exposed to this research.
Data Availability: Data are available from the public sources cited in the text.
JEL Classifications: D22; D80; G10; G12; G14; M41.
Brief Pictorial Quizzes to Assess Carbohydrate Counting and Nutrition Knowledge in Youth With Type 1 Diabetes
Authors: Waheed Myra , Lin Tyger , Thivierge Meredith , Seel Maureen , Prichett Laura , Brown Elizabeth A. , Wolf Risa M. 
Published: June 2022

<p> </p>
<p>Available assessments of patient nutrition knowledge and carbohydrate counting ability are lengthy. This article reports on a study to implement and validate a series of brief nutrition quizzes of varying difficulty for use in pediatric type 1 diabetes. Among 129 youth with type 1 diabetes, participants completed an average of 2.4 ± 1 of the five quizzes, with a median score of 4.7 of 5. Higher quiz scores were associated with lower A1C (<em>P</em> < 0.001), higher parental education (<em>P </em>= 0.02), and higher income (<em>P </em>= 0.01). Such quizzes can help to identify knowledge gaps and provide opportunities for education, which may improve glycemic outcomes in youth with type 1 diabetes. </p>
Frequency of ketoacidosis at diagnosis of pediatric type 1 diabetes associated with socioeconomic deprivation and urbanization: Results from the German multicenter DPV registry
Authors: Auzanneau Marie , Rosenbauer Joachim , Warncke Katharina , Maier Werner , Kamrath Clemens , Hofmann Thomas , Wurm Michael , Hammersen Johanna , Schröder Carmen , Hake Kathrin , Holl Reinhard W. , Initiative the DPV 
Published: June 2022

<p> </p>
<p><strong>Objective</strong></p>
<p>To investigate whether socioeconomic deprivation and urbanization are associated with the frequency of diabetic ketoacidosis (DKA) at diagnosis of pediatric type 1 diabetes.</p>
<p><strong>Research Design and Methods</strong></p>
<p>Children and adolescents aged ≤18 years, living in Germany, with newly diagnosed type 1 diabetes documented between 2016 and 2019 in the prospective diabetes follow-up registry (DPV) were assigned to a quintile of regional socioeconomic deprivation (German Index of Socioeconomic Deprivation) and to a degree of urbanization (Eurostat), using their residence postal code. With multiple logistic regression models, we investigated whether the frequency of DKA at diagnosis was associated with socioeconomic deprivation or urbanization, and if associations differed by age group, sex or migration status. </p>
<p><strong>Results</strong></p>
<p>In 10,598 children and adolescents with newly diagnosed type 1 diabetes, the frequency of DKA was lowest in the least deprived regions (Q1: 20.6% [95%-CI: 19.0-22.4%], and increased with growing socioeconomic deprivation to 26.9% [25.0-28.8%] in the most deprived regions (Q5) (P for trend <0.001). In rural areas, the frequency of DKA at diagnosis was significantly higher than in towns and suburbs (intermediate areas), or in cities (27.6% [95%-CI: 26.0-29.3%] vs. 22.7% [21.4-24.0%], P< 0.001, or vs. 24.3% [22.9-25.7%], P= 0.007, respectively). The results did not significantly differ by age group, sex, or migration background, or after additional adjustment for socioeconomic deprivation or urbanization.</p>
<p><strong>Conclusions</strong></p>
<p>This study provides evidence that prevention of DKA at diagnosis by means of awareness campaigns and screening for pre-symptomatic type 1 diabetes should particularly target socioeconomically disadvantaged regions and rural areas. </p>
Direct Effect of the Constitution of Ukraine in Focus: Access to the Justice and Judicial Control of the Enforcement of Judgment
Authors: Savchyn M. , Zavydniak A. , Olashyn V. 
Published: June 2022

Proper enforcement of court decisions is part of the general concept of access to justice, as it involves the restoration of violated rights by third parties or public authorities. From the point of view of the supremacy of the constitution and their direct effect, the article analyzes the enforcement of court decisions in relation to access to justice. The first part reveals the relationship between constitutional and international standards of access to justice. The second part highlights the main components of access to administrative justice. The third part of the paper analyzes the standards of due process and judicial control over the execution of court decisions. Since we are talking about judicial control over the execution of a court decision and the execution of such a decision as ways of achieving results for persons who have applied for protection of their rights with a lawsuit, it is worth focusing on the applicants. Such in the enforcement proceedings will be the parties to the enforcement proceedings, or rather one of the parties - the claimant.
Access to justice in the context of the principles of constitutional and international law is interpreted on the grounds that the right to judicial protection is not absolute and may be limited on the basis of proportionality, in particular for reasons of procedural economy, efficiency and effectiveness of legal protection. The concept of access to justice follows from the understanding of the rule of law and Rechtsstaat in their relationship. The components of access to justice are the following: 1) pre-trial settlement procedures, in particular mediation; 2) access to legal aid and court fees; 3) terms of consideration of the case; 4) the procedure for appealing court decisions; 5) efficiency and effectiveness of execution of court decisions. Together, they form the notion of access to justice, which is complete provided that court decisions are effectively enforced within a reasonable time. This is influenced by a number of institutional and procedural factors that depend on the degree of development of the legal culture of society.
Non-compete clause in labor law
Authors: Shumilo M. 
Published: June 2022

The contractual regulation becomes more and more important in the world of work. The dynamic character of improving social relations raises the issue of convergence and adaptation of the certain legal structures of Civil and Labor Law. The Soviet and, by inertia, the Ukrainian Post-Soviet science of Labor Law have made significant efforts to record and deepen the differences between the approaches to the regulation of the labor and civil relations.
In general, a considerable part of these works remain relevant, but in some cases they are hopelessly anachronistic and need doctrinal reversion with due regard to the challenges arising as a result of application of a principle of freedom of contract. In addition, the proclamation of the absolute autonomy of Labor Law in the Private law branches family could be considered as wrong and short-sighted, and could lead to stagnation and degradation of certain legal institutions. Non-compete clause or non-competing agreement is a clear example of the necessity to revise the classical approaches to the regulation of specific labor law elements.
The Article focuses of the main aspects that deserve the special attention of both – the parties to the non-compete clauses and the judges who consider disputes arising from such agreements.
It is about a question of who can be a party to the non-compete agreements; the issue of retribution (additional social and work or additional financial guarantees) for refusing to compete with the employer; reasonable temporal limits (term) of non-competition; spatial (geographical) extension of the scope of conditions of a non-compete clause; inadmissibility of the universal approach; maintaining commitment to the new business owner; dynamic character of the non-competing agreements; provisions of non-disclosure of the confidential information; liability for breach of a non-compete clause; territorial jurisdiction of this type of disputes; consistency of the non-competing agreements with the Ukrainian legislation.
This research paper also provides the examples of case-law, which despite of being contradictory, allows us to trace the certain trends. It contents as well a range of conclusions regarding the legal character of a non-compete clause, the necessity of refraining from applying mono-liability (labor) for the breach of the non-competing agreement conditions. The Article also emphasizes the need to determine the legal framework for this type of agreements.
The term «media-space»: theoretical approach
Authors: Celezniova O. 
Published: June 2022

Determining that the science of information law requires research of theoretical content, aimed in particular at forming a proper terminological apparatus, the author in the article using the method of structural-system analysis attempts to formulate an approach to understanding and interpreting the definition of media space.
Analyzing certain scientific positions on the internal nature of the media space, the author notes that this term is explained without reference to other theoretical constructions, may have differences in interpretation of the content with emphasis on various manifestations of media space, and some narrowing of the content in in some cases, or generalizations – in others. The situation is further complicated by the fact that the term «media space» is widely used not only in the science of information law, but also in other social sciences – philosophy, political science, journalism, sociology and more. Not surprisingly, each of the sciences may have its own (different from the others) interpretation of the same term (in this case – «media space»).
This state of affairs deprives the term «media space» of systemic logic, causes its use where another is needed, distorts the notion of internal meaning.
That is why when defining the term «media space» and clarifying its place in the terminological apparatus, the author proposes to proceed first from the metacategory of the information society, and only then – from such constructions as «information sphere» and «information space». It turns out that the media space is a segment (part) of the information space, and therefore it has features that are characteristic of the information space (the concept of «single – general»). At the same time, the specific distinctive features that determine the separation of this space from the information (subject composition, intangible component, etc.) have been clarified. Accordingly, the signs of territoriality and resourcefulness, the intangible part, the functioning of the media as special subjects of the media space, independence from the inner world of man, direct or indirect influence on human consciousness (people) are revealed.
Parameter optimization for wire-cut electrical discharge machining of stir cast AA6063 alloy/SiC (black and green) using Taguchi method with grey relational analysis
Authors: Raj Kumar R , Prasanna Gnana , Hikku G S 
Published: June 2022

Abstract
The present investigation aimed to determine the optimal parameters for wire-cut electrical discharge machining (WEDM) for stir cast aluminum alloy AA6063 at 850°C reinforced with 10 wt.% green SiC (SiC
g
) and black SiC (SiC
b
) particles. The WEDM machining parameters, such as pulse on time (TON
), wire feed (WF) rate, and flushing pressure (FP) of the resultant stir cast AA6063/SiC
b
and AA6063/SiC
g
composites, were optimized using the Taguchi method with L9 orthogonal array to estimate the responses, such as surface roughness and metal removal rate. Further, through grey relational analysis, the finest parameters for WEDM of AA6063/SiC
b
and AA6063/SiC
g
composites were evaluated as TON
= 50 μs, WF rate = 18 m/min, and FP = 3 MPa. With the optimum parameters obtained, conformational experiments were conducted, and the scanning electron microscopic images were recorded, along with the energy-dispersive X-ray (EDX) spectroscopic data of the worn surfaces and debris. From the EDX mapping images of the machined surface, it was evident that AA6063/SiC
b
displays a more polished surface than AA6063/SiC
g
. However, for applications requiring a high metal removal rate, AA6063/SiC
g
displays better results than AA6063/SiC
b
.
Preimages under a popqueue-sorting algorithm
Authors: Cioni Lapo 
Published: June 2022

Abstract
Following the footprints of what has been done with other sorting devices, we study a popqueue and define an optimal sorting algorithm, called Cons. Our results include a description of the set of all the preimages of a given permutation, an enumeration of the set of the preimages of permutations with some specific properties and, finally, the exact enumeration of permutations having 0, 1 and 2 preimages, respectively, with a characterization of permutations having 3 preimages.
Combinatorial interpretation of Kazhdan–Lusztig basis elements indexed by 45312-avoiding permutations in 𝔖6
Authors: Datko Ashton , Skandera Mark 
Published: June 2022

Abstract
Deodhar [Geom. Dedicata 36, no. 1 (1990)] introduced the defect statistic on subexpressions of reduced expressions in the symmetric group 𝔖
n
to construct an algorithmic description of the Kazhdan–Lusztig basis of the Hecke algebra H

n
(q). This led Billey–Warrington [J. Algebraic Combin. 13, no. 2 (2001)] and the second author [J. Pure Appl. Algebra 212 (2008)] to state very explicit combinatorial descriptions of the basis elements indexed by permutations avoiding certain patterns. We extend the above work by producing an exhaustive list of graphical representations of Kazhdan–Lusztig basis elements indexed by 45312-avoiding permutations w ∈𝔖5, 𝔖6.
Useful Approaches in Training and Developing the Professional Conduct of Land Forces Tactical Operational Leaders
Authors: Minculete Gheorghe , Grigoraş Constantin 
Published: June 2022

Abstract
The professional development of military leaders in accordance with the requirements of global and regional military challenges calls for their continuous education and training that harness the intellectual and practical tools necessary for the success of military action in times of peace, crisis or possible armed conflict, determined over time by the conditions of an unpredictable and unstable world. Regardless of the challenges faced today by NATO and by the military, it is obvious that the leaders of tactical structures must acquire moral and ethical qualities necessary for the leadership of operational military organizations in theatres (areas) of operations characterized by uncertainty and increased risk. This objective of this article is to highlight some aspects related to the tactical military leader’s attributes and competences that typify their professional conduct, which allow them to master the art of effective and successful operational leadership in the context of tactical combat structures These abilities are acquired progressively, during training and throughout military university studies as well as afterwards. Given the technological evolution of tactical combat potential and the need to ensure operational resilience through proactive and anticipatory risk management actions, we can argue that the leadership process characterizing this commander is quite different from the one of the past. Our approach is based on connections with some concepts that are considered familiar, due to the fact that, in the future, the leadership performed by the leader of a tactical operational structure will be increasingly complex and, consequently, will require ongoing learning and training.
Measuring Parent Rated Interest and Deprivation type Curiosity in Swedish Young Children - are they meaningfully distinct?
Authors: Kaneko John Michel 
Published: June 2022

Abstract

Background
Proxy ratings of young children’s curiosity has the potential to be useful for research in Sweden. One such proxy rating is the parent-rating Interest/Deprivation Young Children scale. This scale has previously only been validated in Dutch samples, where it differentiated curiosity dimensions of interest (joyful exploration) and deprivation (reduction of aversive feelings of not knowing).

Objective
The objective of this study was to investigate internal and construct validity of the Swedish version of the Interest/Deprivation Young Children scale.

Method
A translation of the Interest/Deprivation Young Children scale was conducted and then administered to 266 parents in Sweden, who rated their children (4-6-years old) on 10 items, with 5 items each for subscales of interest and deprivation dimensions of epistemic curiosity. Responses were analyzed using confirmatory factor analysis.

Results
Results indicate acceptable internal reliability for deprivation-curiosity items (α = 0.78) and for interest-curiosity items (α = 0.79). For the combined scale score alpha was found good (α = 0.84). However, confirmatory factor analysis failed to differentiate interest and deprivation dimensions of curiosity.

Conclusions
Item revisions are suggested which could be implemented for further investigations. Also, the possibility of using the I/D-YC total score as a more general measure of child curiosity is argued for. An open question is how other dimensions of curiosity might be more viable for proxy ratings of child curiosity.
Dynamics of traumatism, mortality and lethality in damage by sharp objects in Leningrad – St. Petersburg in 1978–2020
Authors: Ivanov I. N. 
Published: June 2022

Purpose of the study. Тo analyze the dynamics of traumatism, mortality and lethality from injuries with sharp objects in Leningrad — St. Petersburg, taking into account economic processes, regulation of the alcoholic beverages market and the capabilities of the ambulance service.Materials and methods. The work is based on archival material of the St. Petersburg State Budgetary Healthcare Institution “Bureau of Forensic Medicine” for 1978–2020.Results and discussion. For 43 years in the evolution of traumatism, mortality and lethality from injuries from sharp objects, periods have been traced: pre-crisis (1978–1990), crisis with phases of rise (1991–1993), turning-point (1994) and recession (1995–2004), exit from the crisis or the beginning of stabilization (2005–2011), post-crisis stabilization (2012–2020). The dynamics of statisti cal indicators was influenced by the anti-alcohol campaign (1985), the destabilization of the alcohol market and the elimination of the state monopoly on alcohol (1990–1992), the restoration of state regulation of the turnover of alcoholic products (1993), and the restriction of alcohol consumption (since 1995), financial and economic crises (1991, 1998, 2008–2009), improvement of the emergency medical service (2004, 2013).Conclusions. Economic crises were accompanied by negative dynamics of traumatism. The destabilization of the alcoholic beverages market was accompanied by an increase in traumatism and mortality. The well-organized work of the ambulance service ensures an acceptable level of lethality and mortality.