bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical Investigation of Water Inflow and Seepage Characteristics in a Tunnel crossing Two Overlapped Parallel Faults
Authors: Wu Jing , Wu Li , Han Yan-hua , Lecturer Sun Miao , Lu Ya-ni 
Published: September 2022

Abstract
Water inflow is one of the main geohazards that threaten the safety of tunnels and other underground projects. Faulted zone is one of the important geological triggers for such events. Numerical investigations on the evolution of flow behavior in tunnels across fault zones are of significance to the predication and prevention of this type of geohazards. In this work, a numerical investigation model with two overlapped parallel faults is established according to the "Three Zones" fault structure theory. The rapid turbulent flow in the fault fractured zone and fault center core is simulated by using the improved Darcy-Brinkman (IDB) seepage model, while the slow laminar flow in ordinary rock zone is described by Darcy equation. The effect of relative position and distance between the tunnel surface and two overlapped parallel faults to the evolutions of pore pressure(P), flow velocity(V), and water inflow rate(Q) around the tunnel excavation surface is studied through several scenarios. Our Numerical investigation results reveals that while the tunnel face is excavated into the fault center core, the fractured zone, the ordinary rock zone, and the center of the overlapped faults, the pore pressure value ahead of the excavation face increases while the flow velocity decreases sequentially. The inflow rate is the largest while the tunnel face is excavated to center of the fault center core and is the lowest in the ordinary rock zone. Moreover, the inflow rate is closely related to the range of the overlapped area between the two parallel faults. The investigation results offer a helpful reference to predicting early warning of water inflow geohazard when a tunnel cross two overlapped parallel faults.
Role of agroforestry parklands in livelihood supports in the rural area of the Sahelo-Sudanian zone in Niger
Authors: Seydou Abdel Nassirou Yahaya , Soulé Moussa , Seydou Abdel Nassirou Yahaya , Soulé Moussa 
Published: September 2022

Abstract
Several studies were made in Niger, but there is little data on agroforestry studies in two relatively different ecosystems. Therefore, the aim is to determine the services provided by agroforestry parklands and carbon stock estimation in the two villages. Firstly, a survey was carried out to highlight the benefits derived from agroforestry parklands to rural populations. Secondly, a forest inventory was used based on a systematic random sampling approach by transect. Finally, the Normalized Difference Vegetation Index (NDVI) was used. The study recorded 25 woody species in Dan Saga and 24 in Sekoukou village where there is more dominance of the Fabaceae family species (43.48% in Dan Saga and 58.34% in Sekoukou) followed respectively by Anacardiaceae and Combretaceae (8.7% and 12.5%). Dendrometric surveys showed relative low tree density (23 stems/ha at Dan Saga and 14 stem/ha at Sekoukou), a bell-shaped diameter structure showing a strong dominance of intermediate diameter trees ([20 cm; 30 cm [) and a low representativeness tree with extreme diameters ([0; 10 cm and [70 cm; → [), The soil cover (more than 50%) and the regeneration rate are more than 80% in both localities. The analysis of variances gives a significant difference (P-value < 0.05) in all dendrometric parameters as well as the carbon content, except for the density and the diameter of the trees. Shannon-Wiener index (intra-ecosystem diversity) and the Pielou equitability index are relatively low but similar to the mean Sørensen index. The estimated carbon stock rises to 5.67 t/ha in Dan Saga and 7.02 t/ha in Sekoukou. The NDVI of the two areas varies from]0; 1 [from 2001 to 2013, thus showing evolutionary vegetation (biomass) dynamic characterized by low vegetation cover in 2001 but increased in 2013 in both villages.
Foliations formed by generic coadjoint orbits of a class of 7-dimensional solvable Lie groups
Authors: Tuyen Nguyen , Le Vu , Nguyen Tuan 
Published: September 2022

Abstract
We consider all connected and simply connected 7-dimensional Lie groups whose Lie algebras have nilradical g5,2 = span{X1, X2, X3, X4, X5 : [X1, X2] = X4, [X1, X3] = X5} of Dixmier. First, we give a geometric description of the maximal-dimensional orbits in the coadjoint representation of all considered Lie groups. Next, we prove that, for each considered group, the family of the generic coadjoint orbits forms a measurable foliation in the sense of Connes. Finally, the topological classification of all these foliations is also provided.
Identification of key biomarkers and immune infiltration in the thoracic acute aortic dissection by bioinformatics analysis
Authors: Luo Jun , Shi Haoming , Ran Haoyu , Zhang Cheng , Wu Qingchen , Shao Yue 
Published: September 2022

Abstract
Background
Thoracic acute aortic dissection (TAAD), one of the most fatal cardiovascular diseases, leads to sudden death, however, its mechanism remains unclear.
Methods
Three Gene Expression Omnibus (GEO) datasets were employed to detect differentially expressed genes (DEGs). A similar function and co-expression network was identified by weighted gene co-expression network analysis (WGCNA). The least absolute shrinkage and selection operator (LASSO), random forest, and support vector machines-recursive feature elimination (SVM-RFE) were utilized to filter diagnostic TAAD markers, and then screened markers were validated by quantitative real-time PCR (qRT-PCR) and another independent dataset. CIBERSORT was deployed to analyze and evaluate immune cell infiltration in TAAD tissues.
Results
Twenty-five DEGs were identified and narrowed down to three after screening. Finally, two genes, SLC11A1 and FGL2, were verified by another dataset and qRT-PCR. Function analysis revealed that SLC11A1 and FGL2 play significant roles in immune-inflammatory responses.
Conclusion
SLC11A1 and FGL2 are differently expressed in aortic dissection (AD) and may be involved in immune-inflammatory responses.
Effect of low fuel temperature on combustion deterioration of kerosene swirling spray flame
Authors: Xin Shirong , He Yong , Liu Tao , Wu Yingchun , Wu Xuecheng , Wang Zhihua 
Published: September 2022

Abstract
Low temperature and low air pressure would cause low fuel inlet temperature and low air flowrate in aero-engine combustion chamber working in the upper atmosphere. A system including a burner normally used in actual aero engines is established to study swirl-stabilized kerosene spray combustion at conditions of low fuel inlet temperature (T < − 16 ℃) and low air pressure. According to analysis of OH-PLIF images, sub-zero Celsius significantly results in the reduction of the OH radical concentration and poor heat release rate. The strongest signals decrease by at least 5 times. With analysis of LIF spectroscopy and detuned images, fuel LIF particles in the OH-PLIF images are mainly liquid kerosene LIF. The LIF signals of flame structure are almost all from OH radicals. Using LOG operator blob detection, it is found that, when at sub-zero Celsius, the total number of fuel LIF particles slightly decreases and the number of large particles increases at any air pressure. PLIF analysis in this study provides insight into complex combustion deterioration of kerosene swirling spray combustion for the first time.
Are more aggressive treatments associated with better prognosis among patients with young-onset rectal cancer?
Authors: Yang Yun , Tian Mingwei , Feng Zhewen , Gu Xiaozhe , Li Jun , Wang Hao , Bai Zhigang , Yao Hongwei , Yang Yingchi , Zhang Zhongtao 
Published: September 2022

Abstract
Purpose: The incidence of rectal cancer in young adults is gradually increasing. Patients with young-onset rectal cancer tend to receive more aggressive treatment than older patients. However, the results of studies on the prognosis of patients with young-onset rectal cancer are controversial. This study aimed to retrospectively investigate the prognosis and treatment of patients with young-onset rectal cancer, compared with the older group.
Methods:Patients diagnosed with rectal cancer who underwent curative surgical resection between 2015 and 2019 were enrolled. Propensity-matched sex and clinical stage were used to compare prognoses between young-onset and older groups.
Results: A total of 604 patients were enrolled. Among them, 73 were aged 50 years or less, and 531 were over 50 years of age. After matching, 73 young-onset patients and 146 older patients (>50 years) were identified. More aggressive treatments were administered in the young-onset group than those in the older group, including neoadjuvant therapy (32.9% vs. 17.8%; P=0.012) and adjuvant therapy (74.0% vs. 42.5%; P<0.001). However, there were no significant differences in overall survival and progression-free survival. In subgroup analysis, young-onset female patients showed surprisingly worse outcomes than those in older female patients (P=0.008). Moreover, females in the young-onset group had worse outcomes than males (P=0.033).
Conclusions: With more aggressive treatment, patients with young-onset rectal cancer do not seem to have a better oncologic outcome than older patients. More precise and individualized treatment may be needed for patients with young-onset rectal cancer.
Timely sown maize hybrids enhance the post-anthesis dry matter accumulation and remobilization, nutrient acquisition and crop productivity
Authors: Zhiipao R. R. , Pooniya Vijay , Biswakarma Niraj , Kumar Dinesh , Shivay Y. S. , Dass Anchal , Mukri Ganapati , Lakhena K. K. , Pandey R. K. , Bhatia Arti , Govindasamy Prabhu , Burman Anamika , Babu Subhash , Jat R. D. , Dhaka A. K. , Swarnalakshmi Karivaradharajan 
Published: September 2022

Abstract
Delayed sowing of maize hybrids could exacerbate the capability of maximizing the yield potential through poor crop stand, root proliferation, nutrient uptake, and dry matter accumulation coupled with the inadequate partitioning of the assimilates. This study appraised the performance of five recent maize hybrids viz., PMH-1, PJHM-1, AH-4158, AH-4271, and AH-8181 under timely and late sown conditions of the irrigated semi-arid ecologies. Timely sowing had the grain and stover yields advantage of 16-19% and 12-25%, respectively over the late sown maize hybrids. The advanced hybrids AH-4271 and AH-4158 had higher grain yields than the others. During the post-anthesis period, a greater dry matter accumulation and contribution to the grain yield to 16% and 10.2%, respectively, was observed under timely sown conditions. The nutrient acquisition and use efficiencies also improved under the timely sown. The nutrient and dry matter remobilization varied among the hybrids with AH-4271 and PMH-1 registering the greater values. The grain yield stability index (0.85) was highest with AH-4158 apart from the least yield reduction (15.2%) and stress susceptibility index (0.81), while the maximum geometric mean productivity was recorded with the AH-4271 (5.46 Mg ha–1). The hybrids AH-4271 and PJHM-1 exhibited improved root morphological traits, such as root length, biomass, root length density, root volume at the V5 stage (20 days of sowing, DAS) and 50% flowering (53 DAS). Thus, timely sowing and appropriate hybrids based on stress tolerance indices resulted in greater yields and better utilization of resources.
Utility of the Total Thrombus-formation Analysis System as a tool for evaluating thrombogenicity and monitoring antithrombotic therapy in pediatric Fontan patients
Authors: Matsuo Osamu , Ishii Masanobu , Kaikita Koichi , Morinaga Jun , Miyamura Fumiya , Matsumoto Shiro , Tsujita Kenichi , Nakamura Kimitoshi 
Published: September 2022

Abstract
Background: Despite the major clinical complication of thromboembolic events after the Fontan procedure, there is no consensus regarding the optimal antithrombotic therapy. Novel tools to assess thrombogenicity are desirable to establish optimal thromboprophylaxis in this patient population. The Total Thrombus-formation Analysis System (T-TAS) was developed for the quantitative analysis of thrombus formation using microchips with thrombogenic surfaces. This study evaluated the utility of T-TAS in the assessment of thrombogenicity in pediatric Fontan patients.
Methods and results: The participants included 20 consecutive Fontan patients who underwent cardiac catheterization and 30 healthy controls. Blood samples collected without and with antithrombotic therapy (aspirin or aspirin and warfarin) were used for T-TAS to compute the area under the curve (AUC) in the atheroma (AR10-AUC30) and platelet (PL18-AUC10) chips. T-TAS values showed that patients in the Fontan group without antithrombotic therapy had lower thrombogenicity than those in the control group (PL18-AUC10, median [interquartile range] 356 [313–394] vs. 408 [392–424]; AR10-AUC30, median [interquartile range] 1270 [1178–1351] vs. 1382 [1338–1421]). Aspirin and warfarin therapies significantly decreased PL18-AUC10and AR10-AUC30, respectively, compared with those of patients without antithrombotic therapy (P<0.001 for each comparison). Subgroup analysis divided by low (<9 mmHg) or high (≥ 9 mmHg) central venous pressure (CVP) showed that CVP affects the reduction in AR10-AUC30with antithrombotic therapy.
Conclusions: T-TAS may be a useful tool for monitoring thrombogenicity and antithrombotic therapy in Fontan patients.
Golgi fucosyltransferase 1 reveals its role in α-1,4-fucose modification of N-glycan in Diatom Phaeodactylum tricornutum
Authors: Xie Xihui , Yang Jianchao , Du Hong , Chen Jichen , Sanganyado Edmond , Gong Yangmin , Wang Wanna , Chen Weizhou , Liu Zhengyi , Liu Xiaojuan 
Published: September 2022

Abstract
Phaeodactylum tricornutum (Pt) is a critical microbial cell factory to produce a wide spectrum of marketable products including recombinant biopharmaceutical N-glycoproteins. N-glycosylation modification of proteins is important for their activity, stability, and half-life, especially some special modifications, such as fucose-modification by fucosyltransferase (FucT). Three PtFucTs were annotated in the genome of P. tricornutum, PtFucT1 was located on the medial/trans-Golgi apparatus and PtFucT2-3 in the plastid stroma. Algal growth, biomass and photosynthesis efficiency were significantly inhibited in a knockout mutant of PtFucT1 (PtFucT1-KO). PtFucT1 played a role in non-core fucose modification of N-glycans. The knockout of PtFucT1 might affect the activity of PtGnTI in the complex and change the complex N-glycan to mannose type N-glycan. The study provided critical information for understanding the mechanism of protein N-glycosylation modification and using microalgae as an alternative ecofriendly cell factory to produce biopharmaceuticals.
Mechanical and Microstructural Properties of Meta-Halloysite-Based Geopolymer Mortars Cured at Room Temperature
Authors: Kaze Cyriaque Rodrigue , Cengiz Özgür , Jiofack Séverin Bidias Keumeka , Makone Charles Eugene , Jindal Bharat Bhushan , Lecomte-Nana Gisèle Laure 
Published: September 2022

Abstract
In this study, meta-halloysite (MH) mixed with an alkaline solution(8, 10, and 12 M) was used as a binder phase to produce geopolymer mortars with alkaline solution/MH ratios of 0.6, 0.7, and 0.8. The flow slump behaviour, setting time, and mechanical properties of the end products were studied at room temperature. The microstructural properties of the geopolymer mortars were evaluated using scanning electron microscopy coupled with energy-dispersive X-ray spectroscopy. The results indicated that the cohesion between the geopolymer binder and quartz sand aggregates improved with an increase in the molarity and alkaline solution/meta-halloysite ratio from 0.6 to 0.8. The corresponding slump and flow values increased from 25 to 118 mm, 14 to 115 mm, and 12 to 102 mm, whereas the setting time increased from 77 to 163 min, 54 to 140 min, and 35to 121 min,respectively, with an increase in the alkaline solution concentration. Increasing the alkaline solution/MH ratio (from 0.6 to 0.8) improved the dissolution of the solid precursor and produced a sufficient amount of geopolymer,ensuring the formation of a dense and compact structure with few accessible voids, thus justifying the reduction in water absorption and porosity. A similar trend was observed in the compressive, flexural, and tensile strengths, which increased with the alkaline activator/solid precursor and curing time (7 and 28 days). The geopolymer mortar samples prepared using 0.8 and 12 M NaOH developed high compressive strength (65 MPa), lower porosity, and lower water absorption.
Wear resistance of Fe 66 Cr 10 Nb 5 B 19 detonation coatings under dry linearly reciprocating conditions and nanoscratch test
Authors: Kuchumova Ivanna D. , Shikalov Vladislav S. , Batraev Igor S. , Borisenko Tatiana A. , Filippov Artem A. , Koga Guilherme Yuuki 
Published: September 2022

Abstract
The Fe66Cr10Nb5B19 alloy coatings with high hardness (~ 850 HV300), low porosity (less 3%), low content of crystalline phase (less 2.5 wt.%), elevated nanohardness (average value 13.7 GPa), and high wear resistance were obtained in a wide range of detonation spraying modes. The results under dry linearly reciprocating sliding wear tests of coatings and stainless steel carried out according to ASTM G 133-05 are presented. The volume loss of detonation coatings obtained at an explosive charge of 50–70%, measured on an optical profilometer, is significantly lower than that of stainless steel. The similar values of volume scratches of Fe66Cr10Nb5B19 coatings obtained at an explosive charge of 40–70% can be attributed to similar values of porosity and content of crystalline phase. The scratch and spalling mechanisms are the main mechanisms of material removal from the coatings.
Clinical Characteristics and Risk factors of Acute Myocardial Infarction in the Elderly after Hip Fracture: A Retrospective Study
Authors: Zhang Yaqian , Fu Mingming , Hou Zhiyong , Wang Zhiqian , Zhang Yingze 
Published: September 2022

Abstract

Background:The purpose of this retrospective study is to investigate the characteristics and determine the risk factors of Acute Myocardial Infarction (AMI) after hip fracture in the Elderly.Methods:We collected clinical data of older patients who suffered hip fracture from January 2019 to December 2020. The data collected include demographic and clinical characteristics, underlying diseases and laboratory results. In AMI patients, we further collectedtypeof myocardial infarctions, clinical symptoms, electrocardiogram (ECG), Killip class and diagnosis method. We identified independent risk factors for AMI after hip fracture using Least absolute shrinkage and selection operator (LASSO) regression and multivariate logistic regression analyses.Results:There are 40 (4.2%) cases developed AMI in all 958 old hip fracture patients. There were 685 (71.5%) female patients and 273(28.5%) male patients. Among 40 AMI patients, 38(95.0%) had Type 2 myocardial infarction (T2MI) and2 (5.0%) had Type 1 myocardial infarction (T1MI). The majority of these ECG were ST segment depression (57.5%). 16(40.0%) AMI patients initially present with chest tightness and 14(35.0%) patients presented asymptomatic. The Killip class of the AMI was mostly Killip I(60.0%). AMI patients were significantly older(age≥80，p=0.030) and had more comorbidities(p=0.001). Most of AMI patients were complicated with hypertension(60.0%), coronary heart disease(CHD) (45.0%), diabetes(42.5%) and more prone to have anemia(71.5%), hypoproteinemia( 52.5%), electrolyte disorders (45.0%), heart failure(42.5%) deep vein thrombosis (32.5%), pneumonia (32.5%). The C-reactive protein (CRP) on admission was higher(p=0.000) and albumin (Alb) (p=0.000) was lower in the AMI group. Higher age (OR 2.187, 95%CI 1.028-4.654), combined with diabetes (OR 5.701, 95%CI 2.411-13.479), hemoglobin (Hb)≤100 g/L(OR 3.969, 95%CI 1.467-10.737), CRP≥40mg/L (OR 7.013, 95%CI 2.865-17.170), and ALb≤35 g/L (OR 2.139, 95%CI 1.030-4.441) were independent risk factors for AMI after hip fracture.Conclusion:Elderly patients who have diabetes are prone to AMI after hip fracture. Higher CRP, lower Hb and Alb at admission also increase the risk of AMI. After traumatic stress, they are more likely to have a variety of complications. It is necessary to strengthen the management of AMI patients to reduce the occurrence of AMI and other complications.
Contribution to the study of water resources in the coastal region of Essaouira, using vertical electrical soundings, electrical resistivity tomography and GIS (Essaouira, Morocco)
Authors: Ouzerbane Zakaria , Essahlaoui Ali , Hmaidi Abdellah El , Ouali Abdelhadi El , Najine Abdessamad 
Published: September 2022

Abstract
The geophysical study using the VES and the ERT, carried out in the coastal area of Essaouira (Morocco), for the purpose of mapping the aquifers by combining the two geo-electrical methods, the results allowed us to determine the lateral and vertical distribution of the geological formations in the study region. Thereafter the exploitation of these results by the decision makers in the choice of the sites likely to be hydrogeologically fertile to answer the need for the inhabitants in resource in water. The synthesis on the evolution of the geological layers, the variations of thickness and to highlight the anomalies which could affect them, the GIS tool makes it possible to draw up maps (VES) and electrical imagery (ERT ) at a depth chosen by data interpolated by Kriging. The analysis of the results shows that the Qsob zone is of paramount hydrogeological interest, it is represented by a very important layer given the great extension of the resistant formations of Plio-Plioctecene and Cretaceous age with significant thicknesses. The area is crossed by the Qsob River which is the main source of supply for these two aquifers. With the communication of the two aquifers by the very abundant and dense electric discontinuities of general directions E-W, NE-SW and NNE-SSW.