bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Exploration and Practices of TusPark in Promoting Business Incubation and Industrial Development
Authors: Wang Jiwu 
Published: July 2022

As a new platform for innovation, China's national university science parks gather a wealth of resources for innovation. They are not only the carriers of new knowledge, technologies and systems, but also that of new cultures. As one of the first batch of national university science parks in China, TusPark, which is backed by Tsinghua University with the active participation of varied entrepreneurial, R&D and financial institutions, has basically developed an ecological network for innovation that is distributed throughout the country. It has become an important platform for further transformation of the scientific and technological achievements of universities, as well as promoting the development of strategic emerging industries.
Focused on TusPark’s functions and roles in advancing startup incubation and industrial development, this paper conducts an in-depth analysis of TusPark’s developmental path, with research based on interviews conducted with people involved in TusPark’s construction and operations, as well as reviewing the developmental history and models of global university science parks with international perspectives and extracting TusPark’s unique developmental path and model. The aim of this paper is to analyse how TusPark, as the science park of China’s top university, blazed a trail for business incubation and industrial development. The paper presents some typical cases and explains TusPark’s major models for business incubation and industry cultivation. It also discusses the main factors of TusPark’s success and explores its approaches for encouraging future development under new domestic and international circumstances.

This article is mainly divided into two parts: The first part mainly introduces historical background, main functions, operation mode, core achievements, success factors and future development prospect of TusPark; the second part briefs planning, construction and the operation management organization TusPark - Tus-Holdings Co., Ltd., including the company's founding background, development history, equity structure, management team and other basic information, as well as the original business model by TusHoldings, that is, building an innovation ecosystem with features of TusHoldings through the "multi-dimensional triple helix" model of government-enterprise-university, park-industry-finance and technology-capital-industry; and the ways to enhance core competitiveness of TusHoldings by building global innovation network, vertical incubation system and innovative industrial clusters.
Skinner Releasing Technique: A Movement and Dance Practice, Manny A. Emslie (ed.) (2021)
Authors: Collinson Penny 
Published: July 2022

Review of: Skinner Releasing Technique: A Movement and Dance Practice, Manny A. Emslie (ed.) (2021)
Charmouth: Triarchy Press, 300 pp.,
ISBN 978-1-91374-329-1, p/bk, £22.50
USO DE MEDICAMENTOS MAGISTRAIS EM UNIDADE DE TERAPIA INTENSIVA NEONATAL
Authors: Rodrigues Calixto Linhares Isabel , Yakabe Clarice , Chiattone Maria Fernanda , Del Llano Archondo Marcia Eugenia 
Published: July 2022

A prescrição de medicamentos magistrais pode trazer muitas vantagens à terapêutica, principalmente em áreas específicas como a neonatologia devido à baixa disponibilidade da forma farmacêutica ideal para as questões clínicas apresentadas por estes pacientes. Este trabalho teve como objetivo analisar a prescrição de medicamentos magistrais orais em Unidade de Terapia Intensiva Neonatal em um Hospital de nível terciário em Neonatologia da cidade de São Paulo. Foi realizado um estudo quantitativo,descritivo e retrospectivo, no período de março de 2020 a fevereiro de 2021, analisando as frequências das prescrições de medicamentos magistrais e as classes terapêuticas. Os fármacos mais manipulados em formulações líquidas foram: espironolactona (31,7%), hidroclorotiazida (17,9%), furosemida (14,2%), sildenafil (14,0%), captopril (10,5%), omeprazol (9,7%) e propranolol (2,0%). De acordo com o sistema de classificação Anatômico Terapêutico Químico (Anatomical Therapeutic Chemical – ATC), o maior número de prescrições corresponde ao grupo C, doenças cardiovasculares. O estudo mostra a importância da adaptação de medicamentos magistrais na UTI neonatal e portanto, a importância da farmacotécnica hospitalar na neonatologia garantindo a eficácia e segurança dos medicamentos.
Monolithic, non-iterative and iterative time discretization methods for linear coupled elliptic-parabolic systems
Authors: Mujahid Abdullah 
Published: July 2022

We compare four numerical methods for the time discretization of linear coupled elliptic-parabolic systems.
The monolithic method arising from an implicit Euler discretization is the primary method for solving the coupled system.
Accelerated solution via non-iterative decoupling is possible by the semi-explicit Euler discretization, using a novel methodology from related delay differential equations. For poroelasticity, the fixed-stress splitting and undrained splitting methods enable iterative decoupled solves.
We present formulations for the iterative methods in an abstract form and compare through numerical experiments the a priori convergence results for the four methods.
Age partitioned and continuous upper reference limits for Ortho VITROS High Sensitivity Troponin I in a healthy paediatric cohort
Authors: Smith Joel , Karlaftis Vasiliki , Hearps Stephen , Chiriano Angela , Monagle Paul 
Published: July 2022

Abstract

Objectives
In adults, the elevation of cardiac troponin (cTn) above the 99th percentile upper reference limit defines myocardial injury. The use and interpretation of cTn in a paediatric population, however, is difficult given the 99th percentile for different assays is not well established. Using paediatric blood samples from healthy neonates, infants and children we derived continuous and partitioned 97.5th and 99th percentiles for the Ortho VITROS hs-TnI assay.

Methods
A total of 328 samples for infants, children and adolescents aged 0–17.8 years were obtained. Age partitioned reference limits were derived in accordance with CLSI EP28-A3C. Continuous reference limits were established as described previously by the HAPPI Kids Study team.

Results
hs-TnI as measured by the Ortho VITROS Assay is highly elevated above the adult 99th percentile at birth and declines to lower levels within the first 6 months of life. The 99th centile upper reference limit for ages 0–3 months was 72 ng/L (90% CI: 52–91) and 9 ng/L (90% CI: 5.2–17.4) for ages 3 months to 18 years. Continuous upper 99th centile reference limits were comparable.

Conclusions
Partitioned and continuous 99th percentiles for hs-TnI were derived for the new Ortho VITROS assay in healthy neonates and older children. This will assist clinicians to appropriately assess for the presence of myocardial injury in this population.
Diagnostic utility of pleural cell-free nucleic acids in undiagnosed pleural effusions
Authors: Zhao Wen , Cao Xi-Shan , Han Yu-Ling , Wen Xu-Hui , Zheng Wen-Qi , Hu Zhi-De 
Published: July 2022

Abstract
Pleural effusion (PE) is a common sign caused by various disorders. Microbiology, histology and cytology are reference standards for these disorders. However, these diagnostic tools have limitations, including invasiveness, high cost, long turnaround time, and observer-dependent. Soluble biomarkers in pleural fluid (PF) are promising diagnostic tools because they are mininvasive, economical, and objective. Recent studies have revealed that some cell-free nucleic acids (e.g., DNA, mRNA, microRNA, and lncRNA) in PF are potential diagnostic markers for many disorders. Here, we review the performance of PF cell-free nucleic acids for differentiating and stratification of PE.
Applications of polyaniline-impregnated silica gel-based nanocomposites in wastewater treatment as an efficient adsorbent of some important organic dyes
Authors: Khan Mahfoozurrahman , Ali Syed Wazed , Shahadat Mohammad , Sagadevan Suresh 
Published: July 2022

AbstractDue to a recent lack of clean water as a result of an increasing water demand, new wastewater solutions are required. Many researchers have looked into the removal of organic dyes from wastewater, with adsorption being an easy and effective method for removing organic and inorganic contaminants from contaminated water. Conjugated modified polymers, primarily polyaniline (Pani), have been widely used in the wastewater treatment because of their unique properties, such as easy synthesis, tunable morphology, porous structure, good electrorheological property, biodegradability, and nontoxic nature. Modified surface polymers are more reactive for the removal of dyes from wastewater and have outstanding dye removal capabilities in the wastewater treatment. This review article elaborates on wastewater treatment by utilizing silica gel-impregnated polyaniline nanocomposites as adsorbents. The use of polyaniline-modified silica gel in dye migration behavior to the most suited system for the resolution of co-existing dyes is referred to as the separation of organic dyes from their mixtures. Adsorption of important organic dyes to optimize conditions for efficient organic dye removal and comparison with another commercially available adsorbent. Chemical modification with the introduction of acidic or basic surface functionality could increase cationic and anionic chemical adsorption, as well as charged organic species such as dyes. The carrier is thus obtained with a chelating reagent on the surface of a silica gel after impregnation with polyaniline.
The Holocaust Museum Guatemala: History and Contemporaneity
Authors: del Valle José Ángel 
Published: July 2022

Abstract
Of the six Latin American Holocaust Museums, the one in Guatemala deserves special attention. The other five in Argentina, Chile, Mexico, Puerto Rico, and Costa Rica also remember the Jewish victims of WWII, but in Guatemala there is an emphasis on the so-called “Holocaust by bullets.” At the Holocaust Museum Guatemala, its founders and director devote special attention to the executions by bullets using auditive and visual effects causing a long-lasting impact on the public. Another highlight of this institution is the efforts made by its educative team to inform the audience not only about the Holocaust but also the genocide committed against the Guatemalan native population during the 1980s.
Identifying Supervisory or Managerial Status in German Administrative Records
Authors: Collischon Matthias 
Published: July 2022

Abstract
Information on individuals holding managerial or supervisory positions within establishments is important for various aspects of labour market research. However, identifying managers or supervisors in German administrative records is not straightforward. This paper uses survey information from the Panel Study Labour Market and Social Security (PASS) to predict managerial or supervisory tasks in administrative records that can be used to enhance the identification of managers and supervisors in the Sample of Integrated Labour Market Biographies (SIAB). Furthermore, I provide an applied example in which I calculate gender differences in the probability to hold a managerial position.
Crystal structre of 1,4-bis(bromomethyl)-2,3,5,6-tetramethylbenzene, C12H16Br2
Authors: Song Wenqi , Zhao Mingxu , Zhu Yanfang , Gao Jianjing , Zhao Yuzhen 
Published: July 2022

Abstract
C12H16Br2, monoclinic, P21/c (no. 14), a = 7.9423(5) Å, b = 4.4163(3) Å, c = 16.8127(10) Å, β = 94.534(4)°, V = 587.87(6) Å3, Z = 2, Rgt
(F) = 0.0376, wRref
(F
2) = 0.1016, T = 173 K.
Inhaled glucocorticoid-induced metabolome changes in asthma
Authors: Daley-Yates Peter , Keppler Brian , Brealey Noushin , Shabbir Shaila , Singh Dave , Barnes Neil 
Published: July 2022

Objective
The aim of this study was toidentify dose-related systemic effects of inhaled glucocorticoids (GCs) on the global metabolome.

Design and methods
Metabolomics/lipidomic analysis from plasma was obtained from 54 subjects receiving weekly escalating doses (µg/day) of fluticasone furoate (FF; 25, 100, 200, 400 and 800), fluticasone propionate (FP; 50, 200, 500, 1000 and 2000), budesonide (BUD; 100, 400, 800, 1600 and 3200) or placebo. Samples (pre- and post-dose) were analysed using ultrahigh-performance liquid chromatography-tandem mass spectroscopy and liquid chromatography-mass spectrometry. Ions were matched to library standards for identification and quantification. Statistical analysis involved repeated measures ANOVA, cross-over model, random forest and principal component analysis using log-transformed data.

Results
Quantifiable metabolites (1971) had few significant changes (% increases/decreases; P < 0.05) vs placebo: FF 1.34 (0.42/0.92), FP 1.95 (0.41/1.54) and BUD 2.05 (0.60/1.45). Therapeutic doses had fewer changes: FF 0.96 (0.36/0.61), FP 1.66 (0.44/1.22) and BUD 1.45 (0.56/0.90). At highest/supratherapeutic doses, changes were qualitatively similar: reduced adrenal steroids, particularly glucuronide metabolites of cortisol and cortisone and pregnenolone metabolite DHEA-S; increased amino acids and glycolytic intermediates; decreased fatty acid β-oxidation and branched-chain amino acids. Notable qualitative differences were lowered dopamine metabolites (BUD) and secondary bile acid profiles (BUD/FF), suggesting CNS and gut microbiome effects.

Conclusions
Dose-dependent metabolomic changes occurred with inhaled GCs but were seen predominately at highest/supratherapeutic doses, supporting the safety of low and mid therapeutic doses. At comparable therapeutic doses (FF 100, FP 500 and BUD 800 µg/day), FF had the least effect on the most sensitive markers (adrenal steroids) vs BUD and FP.
The Blessed Antonio (Patrizi) from Monticiano, Sienna (Italy): Bioanthropological and Palaeohistological Considerations
Authors: Piombino-Mascali Dario , Zink Albert , Maixner Frank 
Published: July 2022

Background: A medieval mummy known as the Blessed Antonio (Patrizi) is held in the church of Saints Peter and Paul at Monticiano, Sienna, central Italy.Objectives: The aim of our investigation was to complete a biological profile of the subject, as well as to assess the impact of deterioration to the concerned remains.Methods: As a follow-up of our bioanthropological, macroscopic approach, two of the samples taken underwent rehydration, fixation, desiccation, paraffin-embedding, and staining according to standard histological techniques applied to mummified remains.Results: The body was determined to be that of an adult male, who showed some pathological changes such as dental calculus and what is suspected to be hallux valgus. The overall preservation of a skin sample revealed damage caused by a post-mortem infestation of insects, while a second, inner sample was identified as lung tissue, and revealed a case of anthracosis.Conclusions: The Blessed Antonio was an adult male, who had poor dental hygiene and was likely exposed to smoke during his lifetime. Damage observed on the remains indicated that a conservation treatment was desirable for the future preservation of the body.
Left Transforming into Right: The Adoption and Interpretation of the Ideas of the Fluxus Movement in Lithuania in the Second Half of the 20th Century
Authors: Zubavičiūtė Dovilė 
Published: July 2022

The article examines how the ideas of the left-wing Fluxus movement were accepted and interpreted in Lithuania in the second half of the 20th century. The matter is that alongside unusual ways of artistic expression, the practices called fluxisms transcended the boundaries of the art field. The analysis has shown that the artistic actions and their content at that time, and especially in the 1980s and 1990s, were based on the quotation, adaptation, and use of Fluxus ideas in Lithuania. Freedom, experimentation, and performativity were intertwined with the political revival movement, the mood of national resistance, and the (self-)ironic relationship with the Soviet era. The ideas of the left avant-garde movement were understood and used for national cultural and political purposes during Lithuania’s revival.
HEALTH EXPENDITURE ANALYSIS IN PATIENTS WITH PREGNANCY-LABOR COMPLICATIONS IN SURABAYA
Authors: Ernawaty Ernawaty , Sri Dewi 
Published: July 2022

Background: Healthcare spending has serious social and economic consequences for familie, such as financial constraints and psychological distress. Expenditure caused by obstetrics complications has an impact on total household spending. One person’s health expenditure can influence their family members’ welfare.
Aims: This study analyzed health expenditure of patients experiencing preeclampsia, eclampsia, and postpartum hemorrhages.
Methods: This study utilized a descriptive observational research design with a cross-sectional approach. The research sample consisted of 135 women who gave birth in November to December 2018. Multistage random sampling was used since the respondents were selected from regions of Surabaya.
Results: Respondents of pregnancy and delivery complication with catastrophic health expenditure was eclampsia suffered by 40 respondents, 71 respondents with medium income financing Rp3,800,000.00, 64 respondents with medium household expenditure (monthly income of Rp2,001,000.00 - Rp3,000,000.00). As many as 62 respondents had social security agency for health without contribution beneficiaries, 62 respondents had one employed family member, and 66 respondents had 5-7 family members.
Conclusions: The majority of respondents in Surabaya in 2019 experienced a 10% increase of total household expenditure while undergoing treatment. The government continues to increase subsidies for health service facilities that mostly serve the indigen population.
THE IMPACT OF THE COVID-19 PANDEMIC ON MATERNAL MORTALITY ATTRIBUTES
Authors: Fatmaningrum Dyah Ayu , Anis Wahyul , Laksana Muhammad Ardian Cahya 
Published: July 2022

Background: The COVID-19 pandemic is a challenge for mothers to access health services in Indonesia. Patient management, referral processes, and maternal screening protocols are the reasons for this issue.
Aims: This study aimed to analyze maternal mortality trends in East Java Province before and during the COVID-19 pandemic.
Methods: This study was conducted using retrospective observation with a cross-sectional design, and samples were selected using a total sampling technique. The number of maternal deaths in East Java was 520 in 2019 and 565 in 2020. The independent variable in this study is the number of maternal deaths, and the dependent variables include age, gravida, place of death, rescue relay, time of death, and maternal complications. The variables of age, place of death, rescue relay, and gravida were assessed using the Chi-square test.
Results: Statistical tests showed a ρ value of 0.195 for age; 0.916 for place of death; 0.646 for rescue relay; and 0.048 for gravida.
Conclusion: Maternal mortality showed different trends before and after the pandemic in East Java. Significant differences in maternal mortality rate are influenced by gravida status.
Aftermath of climate change on Bangladesh economy: an analysis of the dynamic computable general equilibrium model
Authors: Hossain Syed Shoyeb , Delin Huang , Mingying Ma 
Published: July 2022

Abstract
Climate change is widely acknowledged as a serious threat to global development, and Bangladesh is no exception; without a doubt, global warming has placed Bangladesh among the most vulnerable countries. The motivation behind this paper is to examine the effects of climate change by taking into account the changes in temperature and precipitation over time. This paper first evaluates the climate change impact on crop production by using a crop modeling framework and then constructs a dynamic computable general equilibrium (CGE) model. The result of this study finds that average gross domestic product (GDP) decreases by −6.17% and investment declines by −7.76% due to the climate change impact. The impacts of climate change on rice sectors were felt more intensely, increasing prices by 5.82 and 8.11%, reducing output by −3.08 and −3.7% collectively in 2030 and 2050. The agricultural sectors’ output declined more compared to the manufacturing, mining and gas, construction, service and transportation sectors, which indicates declines in agricultural labor and household income. In conclusion, the impact of climate change by analyzing the computable general equilibrium model in Bangladesh had been paid little attention in the past and this paper tried to fill the gaps and provide policy-makers with crucial information and guide government policies.
Analytical solution for supercritical flow in rectangular channel contraction
Authors: Amara Lyes , Carvalho Rita F. , Berreksi Ali 
Published: July 2022

Abstract
Analysis of the supercritical flow pattern in nonprismatic open channels is an important issue in engineering practice and often a challenging question principally due to the oblique standing wave structure. In this paper, an original analytical solution for supercritical free-surface flow in rectangular channel contraction is proposed. The two-dimensional steady depth-averaged shallow water equations are simplified to an asymptotic one-dimensional (1D) unsteady flow problem in the transverse direction. A first-order approximation is then obtained using small perturbation theory, and the 1D asymptotic model is solved analytically using the Laplace integral transformation. The two-dimensional flow field solution is obtained following a compilation of sequence planes in the time domain. Free-surface profiles along the side wall and the channel axis were compared against experimental data. For this, laboratory tests were performed in addition to a comparison with classical experimental results available in the literature. Within the limits underlying the model, good agreement in water surface profiles is obtained by comparing experimental and theoretical predictions. Principal flow features, such as wave amplitude and positions, are well captured, which makes the solution model of interest for the design and analysis of contracted open channels.
Ferroptosis and Hydrogen Sulfide in Cardiovascular Disease
Authors: Wu Ze-Fan , Yan Bin-Jie , Luo Wen , Gui Dan-Dan , Ren Zhong , Ma Yun , Jiang Zhi-Sheng 
Published: July 2022

Abstract:
Ferroptosis, is an iron-dependent cell death, characterized by the accumulation of lipid reactive oxygen species, and various regulatory mechanisms influence the course of ferroptosis. The rapid increase in cardiovascular diseases(CVDs) is an extremely urgent problem. CVDs are characterized by the progressive deterioration of the heart and blood vessels, eventually leading to circulatory system disorder. Accumulating evidence, however, has highlighted crucial roles for ferroptosis in CVDs. Hydrogen sulfide plays a significant part in anti-oxidative stress, which may participate in the general mechanism of ferroptosis and regulate it by some signaling molecules. This review primarily summarized the effects of hydrogen sulfide on ferroptosis and cardiovascular disease, especially its antioxidative stress, and would provide a more effective direction for the clinical study of CVDs.