bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Efficacy of Multidisciplinary Team Co-Management Program for Elderly Patients With Intertrochanteric Fractures: A Retrospective Study
Authors: Fan Jixing , Lv Yang , Xu Xiangyu , Zhou Fang , Zhang Zhishan , Tian Yun , Ji Hongquan , Guo Yan , Yang Zhongwei , Hou Guojin 
Published: February 2022

BackgroundIntertrochanteric fractures increased quickly in past decades owing to the increasing number of aging population. Recently, geriatric co-management was rapidly emerging as a favored clinical care model for older patients with hip fractures. The purpose of this study was to assess the efficacy of a multidisciplinary team (MDT) co-management program in elderly patients with intertrochanteric fractures.MethodsIn this retrospective study, patients were divided into MDT group and traditional orthopedic care (TOC) group according to the healthcare model applied. 249 patients were included in the TOC group from January 2014 to December 2016 and 241 patients were included in the MDT group from January 2017 to December 2019. Baseline data, peri-operative data, and postoperative complications were collected and analyzed using SPSS 21.0.ResultsNo significant differences were observed between the two groups in terms of patient baseline characteristics. Patients in the MDT group had significantly lower time from admission to surgery and length-of-stay (LOS) compared with those in the TOC group. Furthermore, the proportion of patients receiving surgery within 24 h (61.4 vs. 34.9%, p &lt; 0.001) and 48 h (80.9 vs. 63.5%, p &lt; 0.001) after admission to the ward was significantly higher in the MDT group compared with those in the TOC group. In addition, patients in the MDT group had significantly lower proportion of postoperative complications (25.3 vs. 44.2%, p &lt; 0.001), deep vein thrombosis (7.9 vs. 12.9%, p = 0.049), pneumonia (3.8 vs. 8.0%, p = 0.045) and delirium (4.1 vs. 9.2%, p = 0.025) compared with those in the TOC group. However, no significant changes were found for in-hospital and 30-day mortality.ConclusionThe MDT co-management could significantly shorten the time from admission to surgery, LOS, and reduce the postoperative complications for elderly patients with intertrochanteric fractures. Further research was needed to evaluate the impact of this model on patient health outcomes.
Rigid Neuroendoscopy Assisted Hematoma Resection Reduces the Recurrence Rate of Chronic Subdural Hematoma With Mixed Density: A Retrospective Analytic Cohort Study
Authors: Fang Huangyi , Zhang Zhongding , Liu Yiru , Wang Lingfei , Yang Yue , Li Shize , Jing Xiepan , Bai Guanghui , Sheng Hansong 
Published: February 2022

BackgroundThe mixed density hematoma (MDH) has a high recurrence rate in chronic subdural hematoma (CSDH). This study adopted rigid neuroendoscopy assisted hematoma resection to evacuate CSDH and investigated its efficacy as compared with the traditional burr-hole craniostomy (BHC) in CSDH with mixed density.MethodsA retrospective cohort study was conducted at two centers between January 2015 and December 2020. The data of 124 patients who underwent BHC for CSDH with mixed density were collected and analyzed. A total of 41 patients underwent rigid neuroendoscopy assisted hematoma resection (neuroendoscopy group) and 83 patients were treated by the traditional BHC (control group). Follow-ups were conducted 6 months after the surgery.ResultsThere was no significant difference in the baseline characteristics and preoperative CT features between the two groups (p &gt; 0.05). The neuroendoscopy group had a lower recurrence rate than the control group (p = 0.043). Besides the neuroendoscopy group had a higher rate of hematoma evacuation (p &lt; 0.001), less pneumocephalus volume (p &lt; 0.001), shorter hospital stay (p &lt; 0.001) and better Markwalder score (p &lt; 0.001) than the control group within 24–48 h after operation. However, there was no significant difference between the two groups in the incidence of pneumocephalus, Markwalder score (at discharge and 6 months after surgery) and mortality. Moreover, the operation time was longer in the neuroendoscopy group (p &lt; 0.001).ConclusionsWhen compared with the traditional BHC, rigid neuroendoscopy assisted hematoma resection can better reduce the recurrence rate of CSDH with mixed density. Also, it surpassed the results obtained from BHC in reducing the volume of pneumocephalus, improving hematoma evacuation rate, promoting short-term neurological recovery, and shortening hospital stays.
Super-Selective Partial Splenic Embolization for Hereditary Spherocytosis in Children: A Single-Center Retrospective Study
Authors: Wang Rui-jue , Xiao Li , Xu Xi-ming , Zhang Ming-man , Xiong Qiang 
Published: February 2022

BackgroundHereditary spherocytosis (HS) is the most common hemolytic anemia due to erythrocyte membrane defects. Total splenectomy is the most effective treatment for moderate or severe HS. As a conservative alternative, partial splenic embolization (PSE) can preserve part of the spleen's function, thus reducing the risk of overwhelming post-splenectomy infection (OPSI) or sepsis, especially for pediatric patients. However, it is not easy to precisely control the scope of interventional embolization, limiting PSE applications. The present study aims to optimize the PSE procedure on smaller, which is named super-selective PSE (SPSE), to improve the controllability and assess the feasibility and effectiveness of SPSE.ResultsThis study was conducted by retrospectively reviewing clinical data from HS patients treated by surgical treatments, which were diagnosed at the children's hospital of Chongqing medical university from January 2015 to December 2019. Patients were divided into two groups according to their treatment preference: SPSE (16 patients) group and total splenectomy (41 patients) group. The mean proportion range of splenic embolism by SPSE was 82.4%, close to the expected value (70–85%). The average hemoglobin value was increased significantly from 6.85 (5.6–8.0) g/dl before SPSE to 12.4 (10.4–13.3) g/dl after SPSE (p &lt; 0.001). All children after SPSE suffered mild post-embolization syndrome, such as pain, fever, and vomiting, which could easily be controlled with appropriate supportive therapy.ConclusionsSuper-selective partial splenic embolization is a safe and effective treatment for moderate or severe HS in children. However, with a longer follow-up, more patients further assess the value of SPSE.
Experimental Study of Infill Walls with Joint Reinforcement Subjected to In-Plane Lateral Load
Authors: Leal-Graciano Jesús Martin , Pérez-Gavilán Juan J. , Reyes-Salazar Alfredo , Valenzuela-Beltrán Federico , Bojórquez Edén , Bojórquez Juan 
Published: February 2022

The results of an experimental study of four infilled frames with brick masonry walls subject to reversal cyclic lateral load are presented. The variables studied were the height to length aspect ratio of the wall and the use of joint reinforcement. The investigation was motivated by the fact that the Mexican code establishes the same specifications about the use of joint reinforcement for infill walls as for confined walls, because there is not enough experimental evidence on joint reinforced infill walls. To investigate the possible interaction of the study variables in the seismic performance of the walls, two pairs of specimens, scaled 1:2, with different aspect ratios (H/L = 0.75, 0.41) were tested. The specimens in each pair were identical except that one of them included steel bars into the bed-joints as reinforcement leading to amount phfyh=0.6 MPa. The infill walls with H/L = 0.41 were included from a previous study. The behavior of the specimens was defined in terms of lateral strength, ductility, displacement capacity, deformation of the joint reinforcement and crack pattern. The results indicate that joint reinforcement increases the strength of the system; however, the increase was more pronounced in longer walls. Ductility was reduced with horizontal reinforcement and this behavior was more important for longer walls. As occurred in confined walls, the joint reinforcement generates a more distributed cracking and reduces the width of the cracks. The experiments are described and this and other results are discussed in detail.
Encuentro internacional de docentes de música de Cuenca, sede de la Universidad Internacional Menéndez Pelayo (UIMP) de Cuenca, España, viernes 13, sábado 14 y domingo 15 de noviembre de 2020
Authors: De la Ossa Martínez Marco Antonio 
Published: February 2022

A pesar de la pandemia, el Encuentro Internacional de Docentes de Música de Cuenca/X Jornadas de Didáctica de la Música y Musicología tuvo lugar entre el viernes 13 y el domingo 15 de noviembre de 2020. De forma lógica, tuvo que adaptar su formato y se desarrolló en línea. Así, se desarrollaron cuatro conferencias grupales y treinta y cinco comunicaciones. Organizado por el festival Estival Cuenca y la sede de Cuenca de la Universidad Internacional Menéndez Pelayo (UIMP), el congreso estuvo patrocinado por el Consorcio Ciudad de Cuenca, la Junta de Comunidades de Castilla-La Mancha y el Departamento de Didáctica de la Educación Física, Artística y Música de la Universidad de Castilla-La Mancha. Todas las actividades se emitieron en directo en el canal de YouTube de Estival Cuenca y en el del Encuentro Internacional de Docentes de Música de Cuenca. Su principal objetivo fue propiciar un diálogo en pos de la unión y puesta en valor de la educación y la formación musical en todas las etapas educativas: asociaciones, agrupaciones, educación infantil, primaria, secundaria, escuelas de música, escuelas creativas, conservatorios o universidad.
Various sources of distraction during analogical reasoning
Authors: Kucwaj Hanna , Ociepka Michał , Chuderski Adam 
Published: February 2022

AbstractReasoning by analogy requires mapping relational correspondence between two situations to transfer information from the more familiar (source) to the less familiar situation (target). However, the presence of distractors may lead to invalid conclusions based on semantic or perceptual similarities instead of on relational correspondence. To understand the role of distraction in analogy making, we examined semantically rich four-term analogies (A:B::C:?) and scene analogies, as well as semantically lean geometric analogies and the matrix task tapping general reasoning. We examined (a) what types of lures were most distracting, (b) how the two semantically rich analogy tasks were related, and (c) how much variance in the scores could be attributed to general reasoning ability. We observed that (a) in four-term analogies the distractors semantically related to C impacted performance most strongly, as compared to the perceptual, categorical, and relational distractors, but the two latter distractor types also mattered; (b) distraction sources in four-term and scene analogies were virtually unrelated; and (c) general reasoning explained the largest part of variance in resistance to distraction. The results suggest that various sources of distraction operate at different stages of analogical reasoning and differently affect specific analogy paradigms.
Enrichment of Jupiter’s Atmosphere by Late Planetesimal Bombardment
Authors: Shibata Sho , Helled Ravit 
Published: February 2022

Abstract
Jupiter’s atmosphere is enriched with heavy elements by a factor of about 3 compared to a protosolar composition. The origin of this enrichment and whether it represents the bulk composition of the planetary envelope remain unknown. Internal structure models of Jupiter suggest that its envelope is separated from the deep interior and that the planet is not fully mixed. This implies that Jupiter’s atmosphere was enriched with heavy elements just before the end of its formation. Such enrichment can be a result of late planetesimal accretion. However, in situ Jupiter formation models suggest a decreasing accretion rate with increasing planetary mass, which cannot explain Jupiter’s atmospheric enrichment. In this study, we model Jupiter’s formation and show that the migration of proto-Jupiter from ∼20 au to its current location can lead to late planetesimal accretion and atmospheric enrichment. Late planetesimal accretion does not occur if proto-Jupiter migrates only a few astronomical units. We suggest that if Jupiter’s outermost layer is fully mixed and is relatively thin (up to ∼20% of its mass), such late accretion can explain its measured atmospheric composition. It is therefore possible that Jupiter underwent significant orbital migration followed by late planetesimal accretion.
Les leçons de l’agriculture américaine ?
Authors: Pessis Céline 
Published: February 2022

L’adoption en France d’un modèle américain de modernisation agricole a été particulièrement bien étudiée à propos des politiques de motorisation. Cet article se propose de mettre au jour l’ambivalence de ces « leçons de l’agriculture américaine » par l’étude des craintes de dégradation des sols qui accompagnèrent la généralisation des tracteurs durant la IV e République. En éclairant la circulation de ces alertes parmi les spécialistes du monde rural et la « profession agricole » en voie de structuration, il montre comment, des chambres d’agriculture au Commissariat général au Plan, le souci du sol s’immisça dans la définition d’une bonne politique agricole.
La marchandisation de l’accès à la terre dans des contextes ruraux ouest-africains
Authors: Colin Jean-Philippe 
Published: February 2022

Cet essai propose une lecture de l’émergence et du développement des ventes de terres rurales en Afrique de l’Ouest francophone. Ces transactions n’émergent pas de façon endogène au sein des sociétés locales, mais sont structurées par le rapport entre cédants autochtones et preneurs allogènes. Elles restent souvent socialement enchâssées : le paiement ne clôt pas alors la relation, il l’instaure ou la perpétue. L’existence d’un flux financier ne permet pas dans ce cas de conclure à une vente ferme, définitive, incontestable, d’autant que, sauf exceptions, les transactions concernant les terres rurales se déroulent en déconnexion du cadre légal et restent informelles. Ces transferts fonciers posent la question de l’interprétation, par les parties, de l’objet de la transaction (la terre ou le droit d’exploitation ?) et de son caractère libératoire ou non – en d’autres termes, la vente est-elle « complète » ? La réponse est à apprécier empiriquement en un lieu et un temps donnés. La marchandisation de l’accès à la terre dans les contextes ouest-africains illustre des situations marquées par un pluralisme normatif et institutionnel.
L’accession à la propriété après les séparations : pourquoi un tel écart entre hommes et femmes ?
Authors: Crepin Laure 
Published: February 2022

À partir de l’enquête SRCV (Statistiques sur les Ressources et les Conditions de Vie), cet article se propose de décrire comment les séparations conjugales viennent renforcer les inégalités d’accession à la propriété entre hommes et femmes. Avant la rupture, les femmes ont des carrières moins rémunératrices que leur conjoint. Ces inégalités se creusent après la séparation, d’autant plus que les femmes ont davantage la garde des enfants. Elles ont donc des niveaux de vie plus faibles et des situations professionnelles plus précaires, leur permettant moins souvent de rester propriétaires. Par ailleurs, à caractéristiques égales, les hommes font davantage le choix de la propriété que les femmes, notamment lorsqu’ils sont pères, venant confirmer que les « choix résidentiels » sont genrés.
REL and BHLHE40 Variants Are Associated with IL-12 and IL-10 Responses and Tuberculosis Risk
Authors: Shah Javeed A , Warr Alex J , Graustein Andrew D , Saha Aparajita , Dunstan Sarah J , Thuong Nguyen T T , Thwaites Guy E , Caws Maxine , Thai Phan V K , Bang Nguyen D , Chau Tran T H , Khor Chiea Chuen , Li Zheng , Hibberd Martin , Chang Xuling , Nguyen Felicia K , Hernandez Carlo A , Jones Madison A , Sassetti Christopher M , Fitzgerald Katherine A , Musvosvi Munyaradzi , Gela Anele , Hanekom Willem A , Hatherill Mark , Scriba Thomas J , Hawn Thomas R 
Published: February 2022

Abstract
The major human genes regulating Mycobacterium tuberculosis–induced immune responses and tuberculosis (TB) susceptibility are poorly understood. Although IL-12 and IL-10 are critical for TB pathogenesis, the genetic factors that regulate their expression in humans are unknown. CNBP, REL, and BHLHE40 are master regulators of IL-12 and IL-10 signaling. We hypothesized that common variants in CNBP, REL, and BHLHE40 were associated with IL-12 and IL-10 production from dendritic cells, and that these variants also influence adaptive immune responses to bacillus Calmette–Guérin (BCG) vaccination and TB susceptibility. We characterized the association between common variants in CNBP, REL, and BHLHE40, innate immune responses in dendritic cells and monocyte-derived macrophages, BCG-specific T cell responses, and susceptibility to pediatric and adult TB in human populations. BHLHE40 single-nucleotide polymorphism (SNP) rs4496464 was associated with increased BHLHE40 expression in monocyte-derived macrophages and increased IL-10 from peripheral blood dendritic cells and monocyte-derived macrophages after LPS and TB whole-cell lysate stimulation. SNP BHLHE40 rs11130215, in linkage disequilibrium with rs4496464, was associated with increased BCG-specific IL-2+CD4+ T cell responses and decreased risk for pediatric TB in South Africa. SNPs REL rs842634 and rs842618 were associated with increased IL-12 production from dendritic cells, and SNP REL rs842618 was associated with increased risk for TB meningitis. In summary, we found that genetic variations in REL and BHLHE40 are associated with IL-12 and IL-10 cytokine responses and TB clinical outcomes. Common human genetic regulation of well-defined intermediate cellular traits provides insights into mechanisms of TB pathogenesis.
Ca2+ Signaling Augmented by ORAI1 Trafficking Regulates the Pathogenic State of Effector T Cells
Authors: Wu Beibei , Woo Jin Seok , Sun Zuoming , Srikanth Sonal , Gwack Yousang 
Published: February 2022

Abstract
Activation of the Ca2+ release–activated Ca2+ (CRAC) channel is crucial for T cell functions. It was recently shown that naked cuticle homolog 2 (NKD2), a signaling adaptor molecule, orchestrates trafficking of ORAI1, a pore subunit of the CRAC channels, to the plasma membrane for sustained activation of the CRAC channels. However, the physiological role of sustained Ca2+ entry via ORAI1 trafficking remains poorly understood. Using NKD2 as a molecular handle, we show that ORAI1 trafficking is crucial for sustained Ca2+ entry and cytokine production, especially in inflammatory Th1 and Th17 cells. We find that murine T cells cultured under pathogenic Th17-polarizing conditions have higher Ca2+ levels that are NKD2-dependent than those under nonpathogenic conditions. In vivo, deletion of Nkd2 alleviated clinical symptoms of experimental autoimmune encephalomyelitis in mice by selectively decreasing effector T cell responses in the CNS. Furthermore, we observed a strong correlation between NKD2 expression and proinflammatory cytokine production in effector T cells. Taken together, our findings suggest that the pathogenic effector T cell response demands sustained Ca2+ entry supported by ORAI1 trafficking.
Serratus anterior plane block and erector spinae plane block in postoperative analgesia in thoracotomy: A randomised controlled study
Authors: Hassan Mohamed Elsayed , Wadod Mohamed Abd Alfattah 
Published: February 2022

Background and Aims:
Managing pain after thoracic surgery is crucial and the traditional methods have many adverse effects. We aimed to evaluate serratus anterior plane block (SAPB) and erector spinae plane block (ESPB) in acute pain control in thoracic cancer surgeries.

Methods:
This randomised controlled, triple-blind study was performed on 90 patients, between 18 and 70 years old, scheduled for elective thoracic cancer surgery. Patients were allocated into three equal groups: Control group: received sham ESPB and sham SAPB. SAPB group received SAPB (20 ml bupivacaine 0.5%) and sham ESPB. ESBP group received ESPB (20 ml bupivacaine 0.5%) and sham SAPB.

Results:
Postoperative morphine consumption was significantly lower in ESBP and SAPB groups than control group [ESPB (8.52 ± 4.29 mg) < SAPB (19.57 ± 7.63 mg) < control (36.37 ± 8.27 mg)] (P < 0.001). Numerical rating scale pain score was comparable among the groups at rest, but was significantly lower at 30 min, 2, 4 h in ESPB and SAPB groups, than control group on coughing. The scores were better in SAPB compared to control group till 4 h. At 8, 12, 24 h, the difference between control and SAPB groups became insignificant, but it remained the least in ESPB group. Postoperative forced vital capacity and forced expiratory volume in the first second after 24 h were the best in ESPB group and better in SAPB group compared to the control group.

Conclusion:
Both ESPB and SAPB reduced intraoperative and postoperative opioid consumptions and postoperative dynamic pain scores with improved postoperative pulmonary functions in thoracic surgery with the ESPB being superior.
Teaching Hands-Only CPR (HOCPR) skills to 8th-grade students in urban Bengaluru: Development of a comprehensive Hands-Only CPR programme for high school students
Authors: Ramesh Aruna C. , Hariprasad K.V. , Abhishek K.B. , Murthy M.R. Keshava , Edison Marcia , Hoek Terry L. Vanden 
Published: February 2022

Background and Aims:
Out-of-hospital cardiac arrest is one of the leading causes of death in India. Only 1.3% of these arrests receive bystander cardiopulmonary resuscitation (CPR). Bystander CPR increases a victim’s chances of survival; training school children in Hands-Only CPR (HOCPR) is a proven method of increasing bystander CPR rates. Heart Rescue India is an international project working to improve care for cardiovascular diseases, and as a part of it, a ten module Cardiovascular disease (CVD) educational programme, including HOCPR training, was conducted in ten schools in 2017–18. The objective of our study was to assess the effectiveness of HOCPR training for 8th-grade high school students.

Methods:
Four hundred fourteen of the 530 enroled students from ten schools of Bengaluru participated in the study. The participants attended a one-hour didactic session about the recognition of cardiac arrest and HOCPR in three simple steps. Subsequently, students received hands-on training for HOCPR. The sessions included pre- and post-assessment of knowledge and skills. The results were statistically analysed using paired t-test and the McNemar test.

Results:
The mean overall pre-assessment score for knowledge was 62.07 ± 28.38%, and the post-assessment score was 72.42 ± 26.58% (P < 0.001). In addition, there was a statistically significant improvement in the post-training scores for HOCPR in all three parameters, namely compressions per minute, depth and chest recoil.

Conclusion:
The study demonstrated a simple yet effective HOCPR programme for high school children.