bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Jenis dan Konsentrasi Emulsifier Terhadap Creaming Index Pada Percobaan Margarine dengan Two factors factorial design
Authors: Rochmat Umar Rochmat Umar 
Published: July 2022

Emulsifier pada margarine membantu daya pengembangan margarine yang menghasilkan kue yang lembut dan struktur remah yang homogen. Maka perlu diketahui jenis dan konsetrasi emulsifier yang tepat pada pembuatan margarine. Tujuan dalam penelitian ini yaitu mengetahui pengaruh jenis dan konsentrasi emulsifier terhadap creaming index pada percobaan margarine dengan two factors factorial design. Berdasarkan hasil tabel ANOVA pada kedua percobaan dapat disimpulkan secara umum menunjukkan bahwa jenis emulsifier dan konsentrasi emulsifier menunjukkan pengaruh yang nyata dengan melihat dari semua keragaman F Hitung > F Tabel pada taraf signifikansi 5%. Hasil perhitungan creaming index dengan beberapa pengulangan menunjukkan bahwa hasil optimal pada percobaan single emulsifier yaitu PS-60 0,5% dengan rata-rata creaming index 13,98%. Sedangkan hasil perhitungan creaming index dengan beberapa pengulangan menunjukkan bahwa hasil optimal pada percobaan double emulsifier yaitu UOM + PGE (masing-masing 0,3%) dengan rata-rata creaming index 15,56%.
FORTIFIKASI ENBAL DENGAN TEPUNG IKAN LAYANG SEBAGAI PANGAN FUNGSIONAL KHAS KEPULAUAN KEI, MALUKU TENGGARA
Authors: Tuarita Mirna , Nara Selfia Martha 
Published: July 2022

Southeast Molucca, a regency in Kei Island, is rich in natural resource including nutritious marine foods. These resources are potential for further development as functional ingredient. Enbal, a traditional food in the region, is made from cassava; it contains a large amount of carbohydrate, but limited amount of other nutrients. To enhance nutritional value, fortification using mackerel scad (Decapterus sp) flour into enbal can be a promising option.Naturally, cassava contains active compound skopoletin, while the fish flour is a source of iron (Fe) as a functional ingredient. Functional food represents a type of food containing bioactive compounds enabling to provide beneficial physiological effects on health.
Delayed cerebral pseudoaneurysm following surgical and combined-modality therapy for glioblastoma multiforme: illustrative case
Authors: Krishnakumar Hari N. , Son Colin 
Published: July 2022

BACKGROUND
Post–radiation therapy and chemotherapy cerebral pseudoaneurysms are rare entities. Within previous tumor treatment areas on nonvascular imaging, they are potentially confused as recurrent tumor.

OBSERVATIONS
A 61-year-old man was a long-term survivor of glioblastoma multiforme whose treatment consisted of open biopsy followed by radiotherapy to 60 Gy and systemic carmustine. On surveillance imaging, enlargement of a posttreatment cyst and new enhancing lateral “mural nodule” was first noticed approximately 16 years after initial treatment. Over 12 months, both continued to enlarge. Initially referred to as recurrence, subsequent angiography showed the mural nodule to be an unruptured distal middle cerebral artery pseudoaneurysm within the previous tumor bed. The patient underwent repeat craniotomy for clipping of the aneurysm and biopsy of the cyst wall, which was negative for malignancy.

LESSONS
Delayed pseudoaneurysms following radiation therapy and chemotherapy for malignant brain tumors are rare but have been previously reported. Their appearance on cross-sectional imaging can mimic recurrence, and they should be kept in the differential of new, circumscribed enhancement within such treatment areas.
Pilocytic astrocytoma of the optic nerve with intracystic hemorrhage in an adult: illustrative case
Authors: Kuramitsu Shunichiro , Suzaki Noriyuki , Takahashi Tatsuo , Murakami Yoshiko , Asai Takumi , Eguchi Kaoru , Ando Ryo , Tamari Yosuke , Ito Shohei , Kimata Masayuki , Terao Kazuichi , Kajita Yasukazu 
Published: July 2022

BACKGROUND
Optic pathway gliomas are uncommon, accounting for 3–5% of childhood brain tumors, and are mostly classified as pilocytic astrocytomas (PAs). PAs of the optic nerve are particularly rare in adults.

OBSERVATIONS
The authors presented the case of PA of the left optic nerve in a 49-year-old woman along with detailed pathological and molecular analyses and sequential magnetic resonance imaging. The tumor had progressed during 5 years of follow-up along with cyst formation and intracystic hemorrhage; it had a thick capsule and contained xanthochromic fluid. The boundary between tumor and optic nerve was unclear. B-type Raf kinase (BRAF) V600E point mutations or translocations, IDH1-R132H mutations, loss of alpha-thalassemia/mental retardation X-linked, and 1p/19q codeletion were negative.

LESSONS
BRAF alterations in pediatric PAs of the optic nerve are less frequent than those observed in PAs in other lesions; the same molecular pattern was observed in the adult case, without changes in BRAF. Surgical management should be indicated only in cases with severely impaired vision or disfigurement because there is no clear border between the tumor and optic nerve. Further discussion is needed to optimize the treatment for adult optic pathway gliomas, including radiotherapy, chemotherapy, and molecular-targeted therapies, in addition to surgical intervention.
Nanostructural glass composite coatings
Authors: Kharchenko S.D. , Kharchenko O.V. 
Published: July 2022

The results of the study of glass-composite nanostructured self-lubricating coatings are presented. The developed glass composite is an antifriction material with an ultrafine structure. The structural components of these coatings significantly affect the graphitization process and provide an antifriction surface layer of α-graphite. The formation of this layer makes it possible to significantly minimize the contact parameters in the friction region.
The developed antifriction nanostructured glass-ceramic self-lubricating coatings containing magnesium carbide and structural components that promote surface graphitization do not contain expensive and scarce components, meet environmental safety requirements, and have high performance characteristics. A significant effect of aluminoborosilicate in the form of a glass phase on the tribological properties of coatings is noted. An increase in adhesive strength is achieved by forming a surface layer of glassy sodium silicate. Using X-ray phase analysis, it was found that the intercalating elements in the subsurface zone-graphite system at the initial stage of the process were Mg2+, Al3+, Cu2+ ions, which randomly penetrated into the interlayer space of the graphite matrix. At sliding speeds of more than 3.0 m/s, intercalates of binary molecular compounds of these elements with oxygen were found in the layered system of graphite. Their intercalation is accompanied by a sequence of repetitive stages, which are reversible with a change in tribological parameters and are characterized by a specific transformation of the structure and, above all, by an increase in the distance between layers due to the influence of various types of interlayer defects and the introduction of intercalants.
The presence of near-surface particles in the graphite layer does not affect the tribotechnical characteristics of the coatings. The developed glass-composite nanostructured self-lubricating coatings have high antifriction characteristics throughout the entire load-speed range
Estimation of tribotechnical parameters of composite polymer with metal filler
Authors: Skvortsov О.О. , Mikosianchyk О.О. 
Published: July 2022

Р
The use of composition material based on the polyamide (caprolon) Ertalon 4.6 as an anti-friction material in the sliding units in the aviation industry is considered. Low carbon electrotechnical sheet steel 21864 of different concentrations was used as filler of composite material. The article presents the thermal calculation of plain bearings with polymer insert in different operating modes. It is determined that the addition of a metal filler to polyamide causes a temperature decrease in the friction zone due to the effective heat exchange from the shaft to the bearing housing. The article conducts a study of tribo-technical properties of the proposed composite material on installation PT-4C under sliding conditions according to the scheme “cylinder-plane”, as well as modeling of the support unit in the software complex DS SolidWorks. It has been experimentally determined that the addition of finely dispersed steel filler enhances the antifriction properties of the Ertalon 4.6 polymer and extends the temperature range of the composite insert performance. Increasing the filler concentration to 20% results in a reduction of the friction coefficient by an average of 3.6 times and an increase in the temperature range of composite material use to 100 °C. The load-bearing capacity of the composite material bushing is increased to 25 MPa at a 20% filler concentration respectively.
The practical significance of the work lies in the analysis of the antifriction properties of the polymer with metallic filler in comparison with the polymer without filler, which will prove the effectiveness of the use of such polymers in friction units instead of non-ferrous metals (bronze, babbitt).
Laparoscopic management of pelvi-ureteric junction obstruction caused by aberrant renal vessels in an adult
Authors: Sangoi Chintan , Shetty Prakashchandra , Joshi Abhijit 
Published: July 2022

Pelvi-ureteric junction obstruction is not a rare clinical entity. It is indeed one of the common urological conditions presenting most commonly as hydronephrosis and pain. The most common etiology for patients suffering from acquired pelvi-ureteric junction obstruction is the presence of calculus/calculi. An aberrant renal vessel (now termed as Vascular bar) is one of the causes in adults which is often missed on pre-operative investigations and is detected intra-operatively. We present herein, a case report of a 28 years old female who came with complaints of loin pain since 2 to 3 months. The workup investigations revealed only hydronephrosis without any calculi. Thus a diagnosis of primary pelvi-ureteric junction obstruction was made. The patient was successfully managed by a laparoscopic pyeloplasty.
Keywords : PUJ obstruction, Vascular bar, aberrant renal vessel, laparoscopic pyeloplasty
Increased Knowledge and Attitudes of Preconception Care using the Dedi Torri Application
Authors: Abriyani Ni nyoman Y. , Tri Sunarsih  , Rosida Luluk 
Published: July 2022

Objetive: To determine the increase in knowledge and attitude of preconception care through the application of DeDitorRi.Methods: Uses pre-experiment using a one group pre-test and post-test design.Result: Based on the paired t test in the first health education using the DeDi torRi application to the difference in knowledge obtained with a p value of 0.000 in attitudes with a p value of 0.000. Based on paired t test in the second health education using the DeDitorRi application to the difference of knowledge obtained with a p value of 0.000 and an attitude with a p value of 0.000.Conclusion: Preconception care health education through DeDi torRi (application-based module) and education that is given repeatedly to reproductive age mothers can influence the increase in knowledge and attitude of preconception care.Keywords: health education applications, preconception care, women of reproductive.

Abstrak
Tujuan : Untuk mengetahui peningkatan pengetahuan dan sikap perawatan prakonsepsi melalui aplikasi DeDi torRi. Metode : Pre-eksperimen dengan menggunakan rancangan one group pre-test dan post-test.Hasil: Berdasarkan uji paired t test pada pendidikan kesehatan pertama menggunakan aplikasi DeDi torRi terhadap beda pengetahuan yang didapatkan dengan p value sebesar 0,000 pada sikap dengan p value 0,000. Berdasarkan uji paired t test pada pendidikan kesehatan kedua menggunakan aplikasi DeDi torRi terhadap beda pengetahuan yang didapatkan dengan p value sebesar 0,000 dan pada sikap dengan p value 0,000.Kesimpulan: Pendidikan kesehatan menggunakan aplikasi DeDi torRi (aplikasi berbasis modul) efektif dalam meningkatkan pengetahuan dan sikap pada perempuan usia reproduktif terhadap perawatan prakonsepsi. Kata kunci: aplikasi pendidikan kesehatan, perawatan prakonsepsi, perempuan usia reproduktif.
Influence of Total Hysterectomy to Sexual Function
Authors: Dini Andini Z. , Yusrizal Ferry , Basir Firmansyah , Theodorus  
Published: July 2022

Objective: To determine whether there are differences the impact of total hysterectomy on sexual function between each woman. Women who perform total hysterectomy often experience fear of the negative effects of hysterectomy on their sexual function.Methods: Randomized clinical trials have been conducted in outpatient clinic Obstetrics and Gynecological wards of Dr. Muhammad Hoesin General Hospital, Palembang from February to October 2020. There were 40 samples of women undergoing a total hysterectomy met the inclusion criteria. Sexual function before and after hysterectomy was analyzed with the Wilcoxon test. Data analysis using SPSS version 22.0.Results: This study showed decreased of desire, decreased stimuli, decreased orgasm, increased lubrication, increased sexual satisfaction, and increased dyspareunia samples after a total hysterectomy. However, with statistical analysis obtained results there were no meaningful changes in sexual function of desire (p = 0.849), stimuli (p = 0.716), lubrication (p = 0.261), orgasm (p = 0.839), sexual satisfaction (p = 0.613) and dyspareunia (p = 0.510) after total hysterectomy .Conclusion: It can be concluded that there is no significantly total hysterectomy effect on sexual function, based on FSFI (sexual desire, sexual arousal, lubrication, orgasm, sexual satisfaction, and pain.Keywords: clinical trial, FSFI, hysterectomy, sexual function.

Abstrak
Tujuan: Mengetahui adakah perbedaan dampak histerektomi total pada fungsi seksual antara setiap perempuan. Perempuan yang melakukan histerektomi total sering mengalami ketakutan akan efek negatif histerektomi pada fungsi seksualnya. Metode: Telah dilakukan uji klinis secara acak di poliklinik rawat jalan bangsal Obstetri dan Ginekologi RSUP Dr. Muhammad Hoesin Palembang dari bulan Februari sampai Oktober 2020. Sebanyak 40 sampel perempuan yang menjalani histerektomi total memenuhi kriteria inklusi. Fungsi seksual sebelum dan sesudah histerektomi dianalisis dengan uji Wilcoxon. Analisi data menggunakan SPSS versi 22.0.Hasil: Penelitian ini menunjukkan penurunan hasrat, penurunan rangsangan, penurunan orgasme, peningkatan lubrikasi, peningkatan kepuasan seksual, dan peningkatan dispareunia setelah histerektomi total. Namun dengan analistik statistik didapatkan hasil tidak ada perubahan yang bermakna pada fungsi seksual yaitu hasrat (p=0,849), rangsangan (p=0,716), lubrikasi (p= 0,716), lubrikasi (p=0,261), orgasme (p=0,839), kepuasan seksual (p= 0,613), dan dispareunia (p= 0,510) setelah histerektomi total.Kesimpulan: Dapat disimpulkan bahwa tidak ada pengaruh histerektomi total yang signifikan terhadap fungsi seksual berdasarkan FSFI (hasrat, seksual, gairah seksual, lubrikasi, orgasme, kepuasan seksual, dan nyeri.Kata kunci: fungsi seksual, FSFI, histerektomi, uji klinis.
The Efficacy of Chemotherapy in Advanced-Stage Cervical Cancer on Vitamin A Serum
Authors: Rizal Raissa N. , Sanif Rizal , Novaliani Amirah , Theodorus  
Published: July 2022

Abstract
Objective: To determine the efficacy of neoadjuvant chemotherapy on changes of vitamin A serum in advanced cervical carcinoma patient.
Method: A randomized clinical trial was performed in the Oncology Gynecology Polyclinic and Ward of Dr. Mohammad Hoesin General Hospital, Palembang from September 2019 to September 2020. There were 30 subjects of advanced cervical carcinoma. Vitamin A levels and tumor volume subjects were assessed before and 1 month after 3 cycles of NAC and analyzed using the Paired T Test and Wilcoxon test. The correlation between vitamin A levels and tumor volume was analyzed by using Spearman's Rho test. Data analysis was using SPSS version 22.0.
Results: This study showed statistically not significant increase on vitamin A levels after 3 cycles of NAC chemotherapy (p=0.515). However, there was a significantly decrease in tumor volume after 3 cycles of NAC (p=0.000). In addition, there was a moderate negative correlation between tumor size and vitamin A (r=-0.475; p=0.008).
Conclusion: It can be concluded that there was significantly decrease in tumor volume after 3 series NAC chemotherapy and the smaller tumor size, the higher level of vitamin A serum.
Keywords: cervical cancer, neoadjuvant chemotherapy, randomized clinical trial, vitamin A,

Abstrak
Tujuan: Untuk mengetahui efektivitas kemoterapi neoadjuvan terhadap perubahan kadar serum vitamin A pada karsinoma servik stadium lanjut.
Metode: Penelitian uji klinik tanpa pembanding telah dilakukan di Poliklinik dan Bangsal Onkologi Ginekologi RSUP Dr. Muhammad Hoesin Palembang sejak September 2019 hingga September 2020. Didapatkan 30 sampel karsinoma serviks stadium lanjut. Kadar vitamin A dan volume tumor dinilai sebelum dan 1 bulan setelah 3 siklus NAC dan dianalsis menggunakan uji Paired T Test dan Wilcoxon. Korelasi antara Kadar vitamin A dan volume tumor sampel dianalisis menggunakan uji Spearman Rho’s. Analisa data menggunakan SPSS versi 22.0.
Hasil : Pada penelitian ini terdapat peningkatan tidak signifikan kadar vitamin A setelah kemoterapi (p = 0,515). Terdapat penurunan secara signifikan volume tumor sebelum dan sesudah kemoterapi NAC 3 seri (p = 0,000). Selain itu, didapatkan korelasi negatif sedang yang bermakna antara ukuran tumor dan kadar vitamin A ( r = -0,475 ; p = 0,008).
Simpulan : Disimpulkan bahwa terdapat penurunan volume tumor setelah kemoterapi NAC 3 series dan semakin kecil ukuran tumor maka semakin tinggi kadar vitamin A dalam serum.
Kata kunci: kanker serviks, kemoterapi neoadjuvan, uji klinik tanpa pembanding, vitamin A.
Estradiol on Day Seven is a Good Predictor for Oocyte Maturation Rate in In Vitro Fertilization Program
Authors: Hestiantoro Andon , Putri Betaria , Gunardi Eka R. , Saroyo Yudianto B. , Natadisastra Muharam 
Published: July 2022

Abstract
Objective: to determine which factors influence the rate of oocyte maturation in In Vitro Fertilization (IVF) program.
Methods: A retrospective cohort study was conducted using secondary data from IVF participants at the Yasmin Fertility Clinic, Dr. RSUP. Cipto Mangunkusumo, Jakarta, Indonesia during the period January 2019 to December 2020, as recorded in the InaRepromed archive. The variables analyzed were age, body mass index, and hormone levels on day 1, day 7, and day hCG, with oocyte maturation rate as the main outcome. Correlation test was performed between several variables and the level of oocyte maturation rate and followed by multivariate analysis to assess the factors that were closely related to oocyte maturation rate.
Results: Data from 52 subjects were collected for the study. Positive correlation was observed between oocyte maturation rate and estradiol on day 7 (r = 0.229), while negative correlation was observed between oocyte maturation rate and progesterone/estradiol ratio on day 7 (r = -0.289) and luteinizing hormone on day 1 (r = -0.265). Multivariate analysis revealed that higher estradiol on day-7 was associated with better oocyte maturation rate (p = 0.047).
Conclusion: Higher estradiol level on day 7 was associated with better oocyte maturation rate in IVF.
Keywords: Assisted reproductive technology (ART), estradiol, in vitro fertilization (IVF), progesterone.

Abstrak
Tujuan: untuk menentukan faktor-faktor yang mempengaruhi tingkat pematangan oosit dalam program Fertilisasi InVitro (FIV).
Metode: Desain penelitian adalah kohort retrospektif, menggunakan data sekunder peserta bayi tabung Klinik Fertilitas Yasmin, RSUP Dr. Cipto Mangunkusumo, Jakarta, Indonesia selama periode Januari 2019 hingga Desember 2020, yang tercatat di dalam arsip InaRepromed. Variabel yang dianalisis adalah umur, indeks massa tubuh, dan kadar hormon pada hari ke-1, hari ke-7, dan hari ke-hCG, dengan tingkat maturasi oosit sebagai luaran utama. Dilakukan analisis korelasi antara beberapa variabel dengan tingkat maturasi oosit, dan dilanjutkan dengan analisis multivariat untuk menilai faktor-faktor yang berhubungan kuat dengan tingkat maturasi oosit.
Hasil: Data dari 52 subjek dikumpulkan untuk penelitian ini. Dijumpai korelasi positif antara tingkat maturasi oosit dan estradiol pada hari ke 7 (r = 0,229), sedangkan korelasi negatif diamati pula antara tingkat maturasi oosit dan rasio progesteron/estradiol pada hari ke 7 (r = -0,289) dan hormon luteinisasi pada hari 1 (r = -0,265). Analisis multivariat mengungkapkan bahwa estradiol yang lebih tinggi pada hari ke-7 dikaitkan dengan tingkat maturasi oosit yang lebih baik (p = 0,047).
Kesimpulan: Kadar estradiol yang lebih tinggi pada hari ke 7 dikaitkan dengan tingkat pematangan oosit yang lebih baik pada program FIV.
Kata kunci : Teknologi reproduksi berbantu (TRB), estradiol, fertilisasi in vitro (IVF), progesteron.
High Random Blood Glucose Level before Surgery as a Risk Factor for Recurrent Event in Epithelial Ovarian Carcinoma
Authors: Hapsari Anggiyasti V. , Iskandar Teuku M. 
Published: July 2022

Abstract
Objective : To investigate the high random blood glucose level as a risk factor for recurrent disease in EOC patient at Kariadi General Hospital.
Methods: Sixty six patients diagnosed as EOC in Kariadi General Hospital were divided into 2 groups: 30 patients with recurrent disease and 30 patients without recurrent disease after completing chemotherapy cycles. We analysed correlation between age of diagnosis, tumour mass location, Ca-125 level, histological subtype and random blood glucose level before surgery with recurrent disease.
Result: There is no significantly difference in age of diagnosis, tumour mass location and histological subtypes between two groups. However, recurrent EOC patients have higher Ca-125 level significantly than non-recurrent patients (327.8±250.5 vs 183.5±212.1 respectively; p = 0,01). Mean of random blood glucose level of recurrent patients is also higher than non-recurrent patients significantly (150.5 ±79 vs 110.8 ± 31.1 respectively; p = 0.006). Patient with random blood glucose level > 110 mg/dl have 3 times more likely to develop recurrence in EOC patient significantly with 95% CI.
Conclusion: The mean of random blood glucose level in recurrent EOC patients is significantly higher than non-recurrent EOC patients. Patient with random blood glucose level > 110 mg/dl have 3 times more likely to develop recurrence in EOC patient.
Keyword: epithelial ovarian cancer, random blood glucose level, recurrent.

Abstrak
Tujuan: Untuk membuktikan kadar glukosa darah sewaktu yang tinggi sebagai faktor risiko kejadian residif pada pasien karsinoma ovarium epitelial di RSUP dr. Kariadi.
Metode: Enam puluh pasien yang telah didiagnosis sebagai karsinoma ovarium epitelial di RSUP dr. Kariadi dibagi menjadi 2 kelompok: 30 pasien pada kelompok residif dan 30 pasien pada kelompok non-residif berdasarkan evaluasi setelah menyelesaikan siklus kemoterapi. Data yang dianalisis meliputi usia saat terdiagnosis, lokasi tumor, kadar Ca-125, subtipe histologi, kadar gula darah sewaktu (GDS) sebelum operasi dan hubungannya dengan kejadian residif.
Hasil: Tidak terdapat perbedaan yang bermakna dalam usia saat diagnosis, lokasi tumor dan subtipe histologis diantara kedua kelompok. Namun, kelompok pasien residif memiliki kadar Ca-125 yang lebih tinggi secara bermakna dibandingkan kelompok pasien non-residif (327,8 ± 250,5 vs 183,5 ± 212,1; p = 0,01). Rerata kadar GDS pada kelompok pasien residif juga lebih tinggi secara bermakna daripada kelompok non-residif (150,5 ± 79 vs 110,8 ± 31,1; p = 0,006). Pasien dengan kadar GDS > 110 mg/dl memiliki risiko 3 kali lipat untuk menjadi residif secara bermakna dengan tingkat kepercayaan 95%.
Kesimpulan: Rerata kadar GDS pada kelompok pasien residif lebih tinggi secara bermakna dibanding kelompok pasien non-residif. Pasien dengan kadar GDS > 110 mg/dl memiliki risiko 3 kali lipat untuk menjadi residif
Kata kunci: kadar gula darah sewaktu, karsinoma ovarium epitelial, residif.