bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of 1.5% Metformin Gel as an Adjuvant to Scaling, Root Planing, and Curettage for the Treatment of Infrabony Defects in Chronic Periodontitis Patients
Authors: Patil Kuldeep S. , Mahajani Monica , Choudhary Sneha H. , Aldhuwayhi Sami D. , Thakare Amar , Mustafa Mohammed Ziauddeen 
Published: March 2022

Context:
To compare and evaluate clinically and radiographically the efficacy of 1.5% metformin (MF) gel and placebo gel as an adjunct to scaling and root planing (SRP) and Curettage for the treatment of infrabony defects (IBDs) in chronic periodontitis patients.

Subjects and Methods:
The study was conducted randomly on 15 patients of both the genders. Each patient contributed two sites (total 30 sites - Split mouth design) which was randomly assigned to one of the two treatments: (i) Site A (Control Site) in which SRP was done along with curettage and intrapocket application of Placebo Gel and (ii) Site B (Test Site) in which SRP was done along with curettage and intrapocket application of 1.5% MF Gel. The Periodontal status {which included plaque index (PI), sulcus bleeding index (SBI), probing pocket depth (PPD), clinical attachment level (CAL), IBD Depth} was assessed both clinically and radiographically at baseline, 3 months, and 6 months after treatment.

Results:
It was found that there was statistically significant difference in the periodontal status (PI, SBI, PPD, CAL, IBD depth) of the two sites when compared from baseline to 6 months.

Conclusions:
Local delivery of 1.5% MF improves the clinical outcomes of traditional treatment (SRP) and curettage and should be considered particularly as an adjunct to it.
Assessment of Serum Parameters in Stable Coronary Artery Disease Patients in Correlation with Healthy and Chronic Periodontitis Patients
Authors: Sanikop Mukta V , Aspalli Shivanand , G Nagappa , Jabeen Rafia Nawab , Aspalli Nagaveni , Babu C. Hemachandra 
Published: March 2022

Background:
Periodontitis is a chronic inflammatory disease and has been strongly associated with elevation of systemic markers such as C-reactive protein (CRP), fibrinogen (FIB), and lipid profile, which have also been significantly associated with coronary heart disease (CHD). Hence, there is a need to assess the possible association between chronic periodontitis and coronary artery disease.

Materials and Methods:
A study included 100 subjects divided into four groups. Group I: stable coronary artery disease with chronic periodontitis, Group II: stable coronary artery disease without chronic periodontitis, Group III: chronic periodontitis without coronary artery disease, and Group IV: healthy controls. Gingival index, Russell's periodontal index, pocket depth, and clinical attachment level were recorded. Venous blood was collected from the patients, and serum fibrinogen, CRP, and lipid profile levels were estimated.

Results:
The intragroup comparison of biochemical and periodontal parameters showed statistically significant results with P < 0.05. The intergroup comparison of serum FIB, total cholesterol, high density lipoprotein, low density lipoprotein, and clinical attachment level showed statistical significant results (P = 0.000, P = 0.000, P = 0.001, P = 0.025, and P = 0.000, respectively) between Groups I and III.

Conclusion:
The results of the study indicate that there might a possible correlation between coronary artery disease and chronic periodontitis, but periodontitis-cardiovascular link is complex and difficult to define though there is sufficient evidence for their association. Leakage of pro-inflammatory cytokines from the ulcerated periodontium causes the production of acute-phase proteins by the liver. To prove the relationship, further studies should be considered making use of other markers of inflammation with prospective randomized controlled studies involving large population.
COVID-19 vaccine uptake and vaccine hesitancy in Indian patients with cancer
Authors: Noronha Vanita , Abraham George , Bondili Suresh Kumar , Rajpurohit Annu , Menon Rakesh P. , Gattani Shreya , Trikha Mehak , Tudu Rajanigandha , Kota Kishore Kumar , Singh Ajay Kumar , Elamarthi Prahalad , Panda Goutam Santosh , Rai Rahul Kumar , Krishna Madala Ravi , Chinthala Sravan Kumar , Shah Minit Jalan , Shah Devanshee , Tiwari Atul , Vora Deep Nareshbhai , Tongaonkar Arnav Hemant , John George , Patil Akshay , Menon Nandini Sharrel , Patil Vijay Maruti , Joshi Amit , Banavali Shripad , Badwe Rajendra A. , Prabhash Kumar 
Published: March 2022

Background:
Patients with cancer are at a higher risk of severe forms of coronavirus disease 2019 (COVID-19) and mortality. Therefore, widespread COVID-19 vaccination is required to attain herd immunity.

Objectives:
We aimed to evaluate the uptake of the COVID-19 vaccine in Indian patients with cancer and to collect information regarding vaccine hesitancy and factors that contributed to vaccine hesitancy.

Materials and Methods:
This was a questionnaire-based survey conducted between May 7, 2021 and June 10, 2021 in patients aged 45 years and over, with solid tumors. The primary end points of the study were the proportion of Indian patients with cancer aged 45 years and older who had not received the COVID-19 vaccine, and the reasons why these patients had not received the COVID-19 vaccine. Our secondary end points were the proportion of patients with a history of COVID-19 infection, and the proportion of the patients who had vaccine hesitancy. Additionally, we attempted to assess the factors that could impact vaccine hesitancy.

Results:
A total of 435 patients were included in the study. Of these, 348 (80%) patients had not received even a single dose of the COVID-19 vaccine; 66 (15.2%) patients had received the first dose, and 21 (4.8%) had received both the doses. Approximately half (47.1%) of the patients reported that they took the COVID-19 vaccine based on the advice from a doctor. The reasons for not taking the COVID-19 vaccine could be considered as vaccine hesitancy in 259 (77%) patients. The two most common reasons were fear in 124 (38%) patients (fear of side-effects and of the impact of the vaccine on the cancer/therapy) and lack of information in 87 (26.7%) patients. On the multivariate analysis, the two factors found to be significantly associated with vaccine hesitancy were a lower educational level (OR, 1.78; 95% CI, 1–3.17; P = 0.048) and a lack of prior advice regarding the COVID-19 vaccine (OR, 2.80; 95% CI, 1.73–4.53; P < 0.001).

Conclusion:
Vaccine hesitancy is present in over half of our patients, and the most common reasons are a fear of the vaccine impacting the cancer therapy, fear of side-effects, and lack of information. Widespread vaccination can only be attained if systematic programs for education and dissemination of information regarding the safety and efficacy of the COVID-19 vaccine are given as much importance as fortification of the vaccination supply and distribution system.
Survey and identification of termites (Insecta, Isoptera) using morphological and molecular methods from eastern, central and western Ethiopia.
Authors: Kassaye Ashenafi , Emana Getu Emana Getu , Wakgari Mulatu , Goftishu Muluken , Awol Seid Awol Seid , Montoya Samantha J. , Gile Gillian H. 
Published: March 2022

The subfamily Macrotermitinae are the largest members among the Family Termitidae which are the fungus growing sub-family and Odontotermes are the most abundant genus from the subfamily. The taxonomy of termites is poorly described in Ethiopia. In the present study 168 termite samples were collected from eight locations of Eastern, Western and Central Ethiopia. The collected samples were identified based on morphological and molecular characteristics. Molecular identification was done based on the dna sequence of a portion of the mitochondrial 16S rrna gene. A phylogenetic analysis of the collected samples and the outgroup resulted in a consensus tree with four distinct groups. Geographical distribution of the samples also supported the resulting clades. Odontotermes were the most widely distributed termites from the collected samples. The genetic distance between the sample showed that Odontotermes zambesiensis, Babile 33 is more distantly related with the rest of the samples.
An integrated knowledge-based system for early detection of eye refractive error using data mining
Authors: Birhane Teklay , Teferi Dereje , Mohammed Tariku 
Published: March 2022

Refractive error is one of optical defect in the human visual system. Refractive error is a very common disease these days in all populations and in all age groups. Uncorrected and undetected refractive error contributes to visual impairment, blindness and places a considerable burden on a person in the world. The long use of technological devices such as smart phones also poses a new burden on the human eye. The intensity and brightness of these digital devices open a new door for high prevalence of eye refractive errors. Early medical diagnosis of the disease may help in avoiding complications and blindness. Data mining algorithms can be applied to help in ophthalmology and detection of an eye disease at an early stage. So mining the ophthalmology data in efficient manner is a critical issue. This research work deals with development of an integrated knowledge-based system that helps to detect eye refractive error early and provides appropriate advice for the patients. In this study, the hybrid knowledge discovery process model of data mining that was developed for academic research is used. About 9000 ophthalmology data from selected eye health centers are used to build the model. The sample data was preprocessed for missing values, outliers, and noise. Then the model is built using decision tree (J48 and REPTree) and rule induction (JRip and part) algorithms. The part algorithm has registered better predictive performance with accuracy of 60% and 96.45% for subjective and objective based model evaluation, respectively as compared to J48, REPTree, and JRip. Finally, the knowledge discovered with this algorithm is further used to build the knowledge-based systems. The Java programing language is used to integrate data mining results to knowledge-based system. The performance of the proposed system is evaluated by preparing test cases. Overall, the knowledge based system resulted in 89.2% accuracy. Finally the study concludes that discovering knowledge using data mining techniques could be used as a functional eye refractive error detection system.
Perkembangan gonad ikan betok (Anabas testudineus) betina yang diinduksi ekstrak hipofisa sapi
Authors: Tanbiyaskur Tanbiyaskur , Fitrani Mirna , Fahrudin Muhammad , Lutfi Lutfi , Muslim Muslim 
Published: March 2022

Tujuan penelitian ini adalah untuk mengetahui pengaruh pemberian ekstrak hipofisa sapi terhadap perkembangan gonad induk betina ikan betok (Anabas testudineus). Metode penelitian mengggunakan rancangan acak lengkap, empat perlakuan dosis ektrak hipofisa yakni 0,0; 0,1; 0,3; 0,6 ml/kg. Penyuntikan ekstrak hipofisa secara muscular. Hasil penelitian menunjukan bahwa dosis 0.6 ml/kg, performance perkembangan gonad terbaik, dimana diameter telur 0,640 mm, gonado somatik indek 4,22%, hepato somatik indeks 0,18% dan fekunditas total 6404 telur. Parameter kualitas air selama pemeliharaan ikan berada dalam kisaran yang baik untuk perkembangan gonad ikan betok.
Мodern South Ossetian historiography and its «uncomfortable topics»
Authors: Гассиева M.A. 
Published: March 2022

Рассмотрены аспекты изучения «неудобных тем», которые в советскойнауке не нашли своего объективного отображения, оценки и осмысления. В 90-е годырассекречиваются архивы, пересматривается история советской действительности.«Неудобные» в прошлом вопросы становятся самостоятельным объектом изучения висториографии, в том числе в югоосетинской. В научной литературе и публицистикепоявились работы, осмысливающие геноцид южных осетин в 1920 году и необоснован-ные политические репрессии в 1937–1938 гг.
The aspects of the study of "uncomfortable topics", which in Soviet science have not foundtheir objective refl ection, evaluation and comprehension, are considered. In the 1990s, archiveswere declassifi ed, and the history of Soviet reality was being revised. “Uncomfortable” questions inthe past are becoming an independent object of study in historiography, including South Ossetianhistoriography. Scientifi c literature and journalism have published works interpreting the genocideof South Ossetians in 1920 and unjustifi ed political repression in 1937–1938.
Some notable artifacts of the Faskau necropolis near the village Galiat, Republic of North Ossetia-Alania
Authors: Чшиев В.Т. 
Published: March 2022

В статье рассматриваются археологические материалы известногонекрополя кобанской культуры Кавказа Фаскау, примечательные с точки зрения ихфункционального и ритуального назначения
The article deals with the archaeological materials of the famous Faskau necropolis ofthe Koban culture of the Caucasus, which are noteworthy in terms of their functional and ritualpurpose
Characteristics of minerological and geochemical features of Filizchay stratiform pyritic fi eld (Great Caucasus, Azerbaijan)
Authors: Саттарзаде Н.А. , Новрузов Н.А. 
Published: March 2022

Филизчайское колчеданно-полиметаллическое месторождение, приуро-ченное к нижнеюрским (верхнеплинсбахским) терригенным отложениям, характери-зуется богатым минеральным составом, разнообразием текстурно-структурныхособенностей и широким геохимическим спектром. Основными текстурными типамиколчеданно-полиметаллические руд являются слоисто-полосчатый, массивный, пятни-сто-вкрапленный и прожилково-вкрапленный. Главные рудные минералы – пирит, сфа-лерит, галенит, халькопирит и пирротин – представлены несколькими генерациями.Установлено, что медь, цинк, свинец и серебро являются важнейшими промышленны-ми компонентами руд. Среди промышленно-технологических типов руд самые высокиеконцентрации благородных металлов (Au и Ag) обнаруживаются в окисленных рудах.В природных типах руд месторождения элементами-примеся ми наиболее обогащеныслоисто-полосчатые колчеданно-полиметаллические. Показатели концентраций – эле-ментов примесей и величины количественных соотношений между ними в рудах – могутбыть использованы в качестве геохимических индикаторов физико-химических условийрудоотложения.
Filizchay pyritic-polymetallic fi eld attributed to the Lower Jurassic (Upper Plinsbach)terrigeneous deposits is characterized by rich mineralogical composition, diversity of texturaland structural peculiarities and wide geochemical spectrum. The major textural types of pyriticpolymetallicore are laminated-banded, massive, spotty-impregnated and veinlet-impregnated.The basic ore minerals are pyrite, sphalerite, galenite, chalcopyrite and pyrrhotite represented byseveral generations. Determined that copper, zinc, lead and silver are the major commerciallyvaluable components of ore. Higest concentrations of precious metals (gold and silver) areidentifi ed in oxidized ore of commercial-technological type of ore. In natural ore type the laminatedbandedpyritic-polymetallic ore is the ore type most enriched by elements-impurities. Parametersof concentrations of elements-impurities and values of their quantitative ratios can be used asgeochemical indicators of physical and chemical characteristics of ore deposition.
Nivel de conocimientos sobre hipertensión arterial (HTA) de adultos de una comunidad rural de Nayarit
Authors: Quiroz Alejandrina Montes , Cortes Erendida Leal , González Delia Esperanza Sillas , Guerrero Verónica Benítez , García Martha Ruiz , Lemus Lucia Magaña , Paz Juana Edelia Vidalez , Saucedo Katery Carvajal 
Published: March 2022

Introducción: La hipertensión arterial es una enfermedad de carácter crónico y silencioso que avanza lentamente y comienza a manifestarse cuando el problema ya es grave; su etiología es multifactorial, e incluyen: vida sedentaria y mala alimentación. Objetivo: Identificar el nivel de conocimientos que poseen adultos de una comunidad rural de Nayarit sobre hipertensión arterial y la prevención de sus complicaciones. Material y métodos: Descriptivo, transversal y prospectivo, la recolección de datos se llevó a cabo en abril y mayo del 2017, a 64 pacientes adultos de un centro de salud rural de Nayarit. Resultados de los participantes 31.25% concluyó la primaria, 29.68% la secundaria, 25% la preparatoria y 14% una licenciatura. El 100% conocía que era hipertensión, sin embargo, el 67.18% asoció la diabetes y el colesterol alto como factores de riesgo para HTA. Conclusiones: Se presenta una deficiencia de conocimientos en los factores de riesgo para la HTA y su tratamiento farmacológico.
A Mixed Methods Analysis of Two Inexpensive and Simple Aquaponics Systems for School Use
Authors: Bush Zain , Stewart Mare 
Published: March 2022

Aquaponics is the conjoined farming of fish and plants in the same system. Researchers have found that aquaponics can provide many educational and nutritional benefits to schools such as educational opportunities and access to fresh food, but many schools lack the funds to build them (School Systems, n.d.). This finding from previous studies sparked this study’s question: How Can a High School Student with Little to No Building Experience, Construct an Inexpensive and Reliable Aquaponics System for School Usage?
To answer this question a convergent parallel mixed study was conducted, comparing the fish and plant growth, ease of maintenance, and construction of 2 different aquaponics systems, one of a raft design and another based on a pipe design.
It was concluded that a pipe system would be better for schools, as it resulted in a better growth rate of both plants and fish, along with lower costs, easier maintenance and simpler construction.
GOVERNMENT MEASURES ON CORRECTING THE CONDITIONS FOR THE ABOLITION OF SERFDOM IN BELARUS IN CONNECTION WITH THE UPRISING OF 1863–1864
Authors: Ratsko Alexander F. 
Published: March 2022

The uprising of 1863–1864 frightened the ruling circles of Russia
greatly. The article examines the measures of the state aimed at attracting the Belarusian peasantry to its side, taking into account their interests and attitudes. It is noted that state measures to adjust the conditions for the abolition of serfdom did not completely solve the peasant issue in the region and did not make local peasants a
reliable social support for tsarism.
THE LIFE AND SCIENTIFIC ACTIVITY OF VASILIY KUPREVICH (BASED ON MATERIALS OF THE BELARUSIAN STATE ARCHIVES OF FILMS, PHOTOGRAPHS AND SOUND RECORDINGS)
Authors: Tratsiak Alena I. 
Published: March 2022

Vasiliy Kuprevich was an academician of the Academy of Sciences of the BSSR, a corresponding member of the Academy of Sciences of the Soviet Union, doctor of biological sciences, professor, had the title “Hero of Socialist Labour”. From
1952 to 1969 he was the president of the Academy of Sciences of the BSSR. Starting from 1958 he was the head of the Non-vascular Plants Physiology and Systematics Department. His scientific interest included physiology of infected plants, systematics of fungi, enzymology of soil, the process of an organism aging at the cellular level. Kuprevich’s scientific activity gave start to the new direction in soil-study – enzymology. In the collection of the Belarusian State Archives of Films, Photographs and Sound Recordings his work is covered by audiovisual documents such as TASS and BelTA photo chronicles, photo libraries of the republican newspapers, newsreels “Soviet Belarus” and “News of the Day”, a documentary film “Life is the Search” and phono records of his lectures.
THE BELARUSIAN FREE ECONOMIC SOCIETY: ORGANIZATIONAL AND FINANCIAL ASPECTS OF ITS CREATION AND OPERATION
Authors: Yerashevich Aliaksandr V. 
Published: March 2022

The article reveals the reasons, conditions of creation, as well as
organizational and financial aspects of activities of the Belarusian Free Economic Society, the first official legal voluntary agricultural association of shareholders from among the landowners of Vitebsk and Mogilev governorates in 1826-1841. The emphasis is placed on finding out the circumstances of the opening and dynamics of financial support for the activities of this organization.
Cardiovascular Spectrum and Cardiac Biomarkers in Pediatric Inflammatory Multisystem Syndrome with Kawasaki-Like Disease - Our Experience During the COVID-19 Pandemic in the West Part of Romania
Authors: Doros Gabriela , Bataneant Mihaela , Mihailov Delia , Popoiu Anca , Stroescu Ramona , Steflea Ruxandra , Vartop Andreea , Stolojanu Cristiana , Micsescu-Olah Andrada-Mara 
Published: March 2022

Abstract

Aim
In COVID-19 Pandemic, a new hyperinflammatory syndrome was reported with clinical features of Kawasaki disease, named PIMS-TS. We want to present a single center experience where the patients were diagnosed with Kawasaki-like in PIMS-TS with cardiac affliction.

Material and method
The study was observational and retrospective, enrolled 14 patients fulfilling the criteria of PIMS-TS with the median age of 9 (IQR, 1.6–11), 9 male (64.2 %) and 5 female (35.8 %).

Results
ECG revealed tachycardia and ST-T changes in 60% of patients. In evolution, ECG modified in 20% and consisted of long QT in 7% of cases, bradycardia in 7%, 3% transitory sick sinus syndrome and 3% grade I/II degree atrio-ventricular block. Cardiac disfunction was evidenced in 4 patients (28%), with reduced ejection fraction under 50%, mitral insufficiency in 6 (42.8%), pericardial fluid in 8 (57.1%) and perivascular brightness in 8 (57.1%). The cardiac biomarkers: NT-proBNP (increased in 9), cTroponin T (increased in 7) and cTroponin I (increased in 5) confirmed heart dysfunction. During the hospitalization and under medical treatment, all the modifications recover. Evolution was good for 12 children.

Conclusions
Cardiac dysfunction and myocardial injury were confirmed by elevated cardiac biomarkers. Rapid recognition allows prompt treatment for a good outcome. NT-proBNP, cTroponin T and I are of capital significance in monitoring the myocardial injury, the treatment and evolution of these patients.
Efek Paket Pelatihan Pesan Zewa pada Perilaku Kesehatan Warga PKK dan Ranting Aisyiyah
Authors: Purwati Yuni 
Published: March 2022

During the Covid-19 pandemic, activities outside the home were restricted causing people to rely on ready-to-eat food and food delivery, which increased waste production. People are not aware that waste can pollute the environment, cause health problems, decrease body immunity which facilitates the spread of Covid-19. Training on healthy behavior packages and waste management as an effort to optimize community health and productivity. The aim can be proven the effectiveness of the pesan zewa training (waste management and zero waste movement) on the health behavior of housewives. The method uses a pre-experimental design with a pre-posttest only design approach. The sample method is cluster sampling, consisting of 24 participants. The instrument is a 15-item questionnaire, normality test using Shapiro-Wilk and Wilcoxon Signed Ranks Test analysis. The results showed a significant change in behavior indicated by the results of P value 0.000 <0.005. The provision of pesan zewa training packages through strengthening health protocols, improving environmental health through a plastic diet, making mediocres as a plant medium and eco-enzyme have a positive impact on residents' healthy behavior.