bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effects of dapagliflozin on serum electrolytes concentration in adult male rats
Authors: Al-Mozie'l Muhsin S. G. , Ghanim Waleed K. , Al-Shawi Nada N. 
Published: November 2022

Hyperkalemia hazard is increased in diabetes, especially in patients with renal disease or those receiving angiotensin-converting enzyme (ACE) medications, angiotensin receptor blockers (ARBs) or potassium-sparing diuretics. Also, other diuretics can increase hypokalemia danger. Recently, We assessed the effects of dapagliflozin in ameliorate the serum calcium, sodium, potassium( Ca+2, Na+2, K+ ) and uric acid concentration in adults male rats. In this study were erolled 18 adult male rats randomly assigned to three groups(n=6) as following: control group (I) 0.5 ml/kg B.W of normal saline. Group II and III receive orally by gavage for 30 days 0.53 mg/kg and 1.06 mg/kg B.W of dapagliflozin. The end of experiment the blood were collected for measuring the following parameter: blood glucose, Ca+2, Na+2, K+ ) , and uric acid concentration. The results of the present study revealed the following: there was significant (P≤0.05) increase in body weight, K+, Ca+2 and uric acid concentration of treated II, and III groups compared with control. On the other hand, there was significant (P≤0.05) decrease in Na+2 concentration of treated compared with control. The experiment was concluded that Dapagliflozin in dose dependent pattern produce significant effects in reduction body weight in II and III groups compared with I group, furthermore, shows that changes in serum concentrations of potassium, calcium and uric acid in treated groups compared to normal where as no effects on sodium concentration was found. Also there is no differences in blood glucose concentration in treated group compared to normal, rather than hypoglycemic and all groups are normal groups.
Efficacy of Silver Nanoparticles, Antimicrobial peptides and Blue Light Combination on Healing Infected Wound by Methicillin Resistance Staphylococcus aureus in Rats
Authors: Ibrahim Orooba M. S. , Ayad Zahraa M. , Omar Luma W. 
Published: November 2022

This study was carried out to evaluate the effectiveness of the triple combination of biologically synthesized silver nanoparticles, anti-microbial peptides and visible blue light against pathogenic clinical methicillin resistance Staphylococcus aureus (MRSA) in vivo after inducing full thickness skin injury in the initially induced diabetic rats. This experiment of in vivo study was for evaluation the role of the combinations in promoting wound healing after wound inducing infection using pathogenic MRSA (0.25ml from 1.5 ×108 cfu/ml) in diabetic rats. 108 diabetic rats (aged 8-10 weeks weighing 200-250g) were divided equally into nine groups, (treatment started after the appearance of infection signs). Group A: Negative control group, group B: Positive control group, Group C: infected treated with AgNPs 8µg/ml, group D: infected treated with Gramicidin 16µg/ml, group E: infected treated with blue light for 1 hour, group F: infected treated with combination of AgNPs 0.25µg/ml with blue light for 1 hour, group G: infected treated with combination of Gramicidin 8 µg/ml and blue light for 1 hour, group H: infected treated with combination of AgNPs and Gramicidin 0.25µg/ml, 0.5 µg/ml respectively, group I : infected treated with triple combination of AgNPs ,Gramicidin 0.25µg/ml, 0.5µg/ml respectively and blue light for 1 hour. All groups treated topically daily for three days. Wound healing was assessed by measuring wound contraction at 7, 14 and 21 days post wound induction. Viable bacterial count at 21 day post wound induction. Results were according to data analysis, healing rate of treated rat with the triple combination was significantly (p < 0.001) faster (within 7 days) than treated rat with other double combination and each agent alone. All symptoms returned to near normal values at the end of treatment. In conclusion the topical therapy of the triple combination of AgNPs, visible blue light and antimicrobial peptides promote wound healing process in diabetic infected wound in a short period of time. A new approach can be used to combat serious infections caused by MRSA by combining AgNPs, blue light, and antibiotics.
Histopathological study of effects phenobarbital in Goats
Authors: K Zainab W. , Ali Hanan , Al-zahra Samera Abd 
Published: November 2022

In this data was done to demonstrate the administration of phenobarbital compounds & showed histopathological effects. In this study fourteen of local goats were divided into two groups (each group seven animals) for 60 days. First one were treated phenobarbital injected with 35 mg \kg.B.W.,twice daily ,second group act as control group. These animals were examined internally and externally during adaptation period. After end experimental period scarified the animals, necropsy, preparation of slid by routine technique and examined by light microscope, there are showed different histological changes into tissue of animals treatment with phenobarbital such as degeneration of epithelial cells lining of renal tubules of kidney and thyroid gland congested of central vein with fibrosis in liver ,vacuolated of mucosal layer of rumen, small intestine and pancreas, atrophyseminiferous tubules of testis and lymph node.
Role of CoQ10 on Some Biochemical and Histological Aspects of Kidney in Rats Exposed to Sodium Fluoride
Authors: Al-Okaily Baraa Najim , Mohammed Imtithal Ali 
Published: November 2022

This experiment was aimed to investigate the role of CoQ10 to alleviating the functional alterations of kidney - induced by sodium fluoride (NaF) in male rats. Twenty adult male Wister albino rats were randomly assigned into four equal groups and treated for 42 days daily as follows: first group was received drinking tap water and intubated with DMSO 1% and serving as control (group C); second group ( group G1) received sodium fluoride 100ppm in drinking tap water ; third group (group G2) received sodium fluoride 100ppm in drinking tap water plus intubated 10 mg /Kg. B.W of CoQ10 orally , whereas fourth group ( group G3) intubated 10 mg /Kg. B.W of CoQ10 only. Fasting blood samples were collected at 0, 21, and 42 days of experimental periods. Then sera was isolated for estimated serum creatinine, blood urea nitrogen (BUN) and peroxynitrite radicals concentrations, as well as catalase activities has been measured. At the end of the experiment the animals were sacrificed and sections from the kidney were taken for histopathological examination. The results revealed that rats received NaF (group G1) for 42 days caused significant decrease in body weight and serum catalase activity , while a significant increase in the concentrations of serum creatinine, blood urea nitrogen (BUN) and peroxynitrite radicals accompanied with histopathological alterations of kidney were showed as compared to other experimental groups . On the other hand, administration of CoQ10 to groups G2 showed an improvement of physiological and histological alterations and keeping the kidney functions around the normal levels, manifested its protective effects against deleterious effects of NaF. It could be concluded that these results confirmed the antioxidant properties of CoQ10 against nephrotoxicity induced by NaF in adult rats.
Detection Of Intracellular Adhesion Gene (Icaa And Icad) And Biofilm Formation Staphylococcus Aureus Isolates From Mastitis Milk Of Cow
Authors: Idbeis Hasan I. , Khudor Mohammed H. 
Published: November 2022

In the present study, a total of 75 mastitis milk samples were collected from cow and were analyzed for the presence of S.aureus. The obtained results indicate that this bacterium observed in 26.66%. The study of antibiotic susceptibility test to 9 different antibiotics showed that S. aureus was 100% resistant to penicillin and 100% sensitive to Vancomycin, Gentamycin , Clarithromycin and Chloramphenicol . Whereas for cefoxitin (alternative to methicillin) resistance was 50%.There were a variable resistance percentage for the rest of antibiotics: Tetracycline (30%), Ciprofloxacin and Clindamycin (22%). The biofilm-forming ability of S. aureus was evaluated via microtiter plates and the result revealed that, all the studied isolates were either moderate biofilm producer or weak biofilm producer while the non-biofilm producer and strong biofilm producer were not detected among the tested isolate. PCR analysis was applied to DNA extracted from S.aureus isolates from milk samples .The results of PCR assay revealed that all S.aureus isolates gave positive results for both icaA and icaD genes (100%) with Product size 151 and 211 bp, respectively.
Results of this study indicate that biofilm producing S.aureus have a major role player on the occurrence of bovine mastitis in addition, there were high prevalence of MRSA isolates (50%) in mastitis milk at the study area.
Antimicrobial susceptibility profile of Salmonella enterica isolated from poultry farms using Vitek- 2
Authors: Hassan Esraa Razzaq , Alhatami Abdullah O. 
Published: November 2022

Background: The increase emergence and dissemination of antibiotic resistant Salmonella strains may contribute to a great risk on public health and impair classical treatment regime. The present study is aimed to investigate the prevalence of NTS in feces of broilers in four provinces in Iraq, and the resistance profile of isolates to clinically important antibiotics.
Method: a total of 185 fecal samples were collected during the period from October2017 to March2018, from 28 broiler farms distributed in four governorates (Al- Najaf Al-Ashraf, AL-Qadyssia, Al-Muthana, and Babylon). Suspected Isolates of Salmonella were assayed for, detection of invA gene PCR, antibiotic susceptibility by Vitek-2.
Results: The prevalence of NTS infection in 28 examined poultry flocks was 75,7%. High prevalence rate of NTS was observed in Babylon (91,7%), followed by Al-Qadyssia (72,7%) and Al-Muthana (70%), which significantly differed (P ≤ 0.01) than reported in AL- Najaf (50%). While the isolation rate was 21.6%. All Salmonella isolates were positive for the invA gene. The majority of isolates were resistant to Minocycline (87.5%) and Ciprofloxacin (85%) with P value ≤ 0.01. in addition to these, 55% of strains were resistant to Pipracillin, 52,5% to Ticarcillin (p ≤ 0.05), and 37,5% to Gentamycin. Fortunately, all isolates were susceptible to Amikacin, Meropenem, Imipenem, Piperacillin/Tazobactam and Ticarcillin/Clavulanic acid, followed by 97.5% of strains were sensitive to Ceftazidime, Cefepime and Aztreanam. Twenty (50%) isolates were exhibited multiple resistance to three or more different antibacterial classes with different resistance profiles.
In conclusion, high prevalence of Salmonella and MDR Salmonella was found in broiler farms located in four Iraqi provinces.
Screening pathological study for pulmonary lesions in slaughtered cattle in Al-Najaf abattoir
Authors: Mandeel Zahraa F. , Al-Dabhawi Ahmed H. 
Published: November 2022

This study was conducted in Al-Najaf slaughterhouse, during the period from January to March 2019 to investigate and classify the microscopic changes of pulmonary lesions and comparison between the percentage of different lesions in lung of slaughtered young and adult cattle. Two hundred and twenty cattle were postmortem examined, The specimens from their lung were collected and preserved in buffered formalin 10% and routine staining with H&E stain and special staining with Masson's Trichrome stain were achieved.The results of the microscopic study showed that there were variable pulmonary affections in slaughtered cattle. The microscopic investigation of the lung specimens stained with hematoxylin and eosin stain showed variation in the occurrence of different microscopic lung lesions, arranged from high percentages such as pleural changes (94.5%), bronchopneumonia (68.5%), pneumonia (57%), emphysema (44%), atelectasis (42%), fibrosis (37%), angiogenesis (35%), congestion (32.5%), consolidation (19.5%), haemorrhage (16.5%), hemosiderin deposition (15.5%), hyperplasia (15%) and desquamation (10%) to moderate to low percentages such as tuberculosis (5.5%), hydropic degeneration (4.5%), oedema (4.5%), hydatid cysts (4%), sclerosis (1.5%), abscesses (1%), metaplasia (0.5%) and thrombosis (0.5%).
The main conclusions of our study revealed that there were different pulmonary lesions could be diagnosed as well as there was significant differences between the prevalence of lung microscopic lesions between young and adult cattle
DEVELOPMENT OF AN OPTIMAL CONTROL SCHEME FOR A D-CLASS HIGH-FREQUENCY AMPLIFIER
Authors: Башкиров А.В. , Свиридова И.В. , Хорошайлов Р.Н. 
Published: November 2022

В аудиоусилителях с переключаемым режимом для улучшения качества звука усилителя использовались контуры управления. Поскольку в этих усилителях используется высокочастотная модуляция, необходимо внимательно проектировать контроллер. Кроме того, коэффициент качества выходного фильтра может оказать большое влияние на возможности контроллера по подавлению шума и отслеживанию аудиосигнала. Представлены методы проектирования современного управления высокочастотным усилителем класса D. Разработанный метод управления позволяет легко решить проблему проектирования высокопроизводительного контроллера, когда выходной фильтр имеет высокий коэффициент качества звука. Результаты показывают, что контроллер способен обеспечить явное улучшение общего уровня гармонических искажений с улучшением до 30 раз по сравнению с разомкнутым контуром при явном снижении шума, что позволяет добиться лучшего качества звука. Приведены принципы моделирования пространства состояний и то, как его можно использовать в сочетании с усилителями класса D. Современные методы теории управления будут применены для проектирования и моделирования интегрирующего контроллера с полной обратной связью по состоянию для использования с высокочастотным мостовым усилителем класса D
In audio amplifiers with switchable mode, control loops were used to improve the sound quality of the amplifier. Since these amplifiers use high-frequency modulation, it is necessary to design the controller carefully. In addition, the quality factor of the output filter can have a big impact on the controller's ability to suppress noise and track the audio signal. This article presents design methods for modern management. The developed control method makes it easy to solve the problem of designing a high-performance controller when the output filter has a high-quality coefficient. The results show that the controller is able to provide a clear improvement in the overall level of harmonic distortion with an improvement of up to 30 times compared to an open loop with a clear reduction in noise, which allows for better sound quality. The principles of modeling the state space and how it can be used in combination with Class D amplifiers are given. Modern methods of control theory will be applied to design and simulate an integrating controller with full state feedback for use with a Class D high-frequency bridge amplifier
Formação do artista plástico no Brasil: o caso da Escola de Belas Artes
Authors: Zilio Carlos 
Published: November 2022

A questão central deste estudo situa-se basicamente em tomo da formulação de uma análise críticasobre o processo histórico do ensino de arte no Brasil desde a instalação da Academia Imperial de Belas Artes, em 1816, até os nossos dias. O eixo principal desta análise é a Escola Nacional de Belas Artes da UFRJ, primeiro estabelecimento do gênero no Brasil e que, durante mais de um século, foi o modelo para as demais escolas de arte. A presente investigação desenvolveu-se através de análises do conjunto de regras acadêmicas, que se tomaram um paradigma para o ensino, definindo o estatuto oficial para a formação do artista brasileiro. Os primeiros sinais de ruptura do modelo imposto pela Escola Nacional de Belas Artes têm origem nos conflitos entre os acadê­micos e modernos no interior da Escola, após 1931. A partir de então, apresentou-se uma defasagem crescente entre a realidade da produção artística e o ensino de arte. As questões que a arte moderna trouxe para o ensino artístico modificaram o panorama institucional, criando um "desajuste para o ensino da arte acadêmica, abrindo novos caminhos para a renovação do ensino artístico e exigindo um outro instrumental analitico capaz de assimilar as novas formulações didáticas. A Escola toma-se atuante quando colocada em sintonia com o restante do sistema de arte, buscando, na aproxi­ mação constante com essas outras fontes geradoras do saber, a sua própria dinâmica de renovação.
Considerações sobre a escultura urbana de Richard Serra
Authors: Rodrigues Renato 
Published: November 2022

A interpretação da escultura urbana de Richard Serra tem sido influenciada pelo debate sobre Tilted Arc. Neste ensaio, analisamos as esculturas Twain, Wright's Triangle e Berlin Block for Charlie Chaplin, assim como o projeto escultórico para o P.A.D.C., sugerindo que o artista teria gradualmente inrorporado as relações entre escultura e espaço urbano a sua pesquisa. Nestas análises, consideramos a inserção das obras de Serra em seus contextos arquiteturais e urbanísticos com o objetivo de delinear os transformações ocorridas em sua escultura de sítio específico.
A arte da natureza
Authors: Tiberghien Gilles A. 
Published: November 2022

O artigo discute o interesse artístico pela natureza, pela instabilidade constitutiva de seus elementos, enquanto um fenômeno recente no domínio da arte, problematizando questões relativas à identidade das obras e a sua formalização. As mudanças, no que diz respeito à forma, transformam o "estatuto teórico" da escultura, sendo este uma questão não mais de forma, mas de matéria, não mais de eternidade, mas de duração. Impõe-se assim repensar a arte à luz de categorias que pertencem mais ao domínio da física grega do que da estética clássica, tais como o belo.
Propósito experimental
Authors: Oteiza Jorge de 
Published: November 2022

Mais de quarenta anos após ter recebido o Prêmio Internacional de Escultura da IV Bienal de São Paulo, em 1957, a obra de Jorge de Oteiza ainda é conhecida de poucos, tanto aqui como internacionalmente. Oteiza, que nasceu em Orio, no País Basco, em 1908, ocupa uma posição de extrema singularidade no quadro das correntes construtivas do pós-guerra. Heterodoxa, postulando uma metafísica estranha à estrita racionalidade geométrica, a obra de Oteiza é um dos marcos da escultura moderna. Essa singularidade fronteia questões também abordadas pelo neoconcretismo - o problema do vazio na escultura, entre outros -, com o qual teve contato, em especial por intermédio de Franz Weissman, de quem se tornou amigo. Arte Ensaios publica neste número o texto Propósito experimental, escrito pelo artista especificamente para sua participação na IV Bienal, em que Oteiza expõe de formo veemente, filosófico e dramático suas ideias e conceitos sobre a escultura, que, logo após, em 1959, abandonaria.
O feminino na arte
Authors: Matesco Viviane 
Published: November 2022

Escrito com vistos à publicação num encarte de jornal de circulação diária paralelo à exposição O século das mulheres, realizoda na Casa de Cultura de Petrópolis no segundo semestre de 2000, com curadoria de Luiz Aquila, o texto situa a crescente participação artístico da mulher no século 20 mediante a análise de referências fundamentais para a compreensão do feminino na arte.
Humanitarian Education for peace and individuals in 21st century Russia
Authors: Арапова Е.Д. 
Published: November 2022

Образование и при современных технических электронных возможностях – необходимое занятие для старшеклассника. Автор прослеживает на личном опыте, что межпредметные связи, например сочетание истории и географии или литературы и обществознания в образовательном процессе, в том числе автодидактическом, способствует выработке новых метапредметных навыков. В своем сообщении автор касается таких сюжетов, как спорность важности знания фактов в их неизменности и классичности; отказ от изучения того или иного предмета в старшей школе; сочетание учебы и занятий спортом; удовольствие от учебы; чувство контекста при посещении музеев и памятных исторических мест; навык установления причинно-следственных связей на занятиях историей или обществознанием.
Education is a necessary activity for a high school student even with modern technical electronic capabilities. The author traces from personal experience that interdisciplinary connections, such as the combination of history and geography or literature and social studies in the educational process, including autodidactic, contribute to the development of new meta-skills. In her presentation, the author touches on such subjects as arguing the importance of knowing the facts in their immutability and classics; refusal to study one subject or another in high school; combining study and sports; the pleasure of learning; a sense of context when visiting museums and memorable historical sites; the skill of establishing cause-effect relationships in history or social studies classes.
Síndrome de BRASH con presentación electrocardiográfica no común. Reporte de caso
Authors: Caballero Sevilla Manuel Nicanor , Tene Corona Diana Itzel , Pérez Magaña María Fernanda 
Published: November 2022

Antecedentes. El síndrome de BRASH es una entidad subdiagnosticada, caracterizada por bradicardia, insuficiencia renal, bloqueo aurículo-ventricular (BAV), choque e hiperkalemia. Esta última potencia efectos adversos de betabloqueadores, habitualmente indicados en hipertensión arterial. Además del BAV, se han descrito otras alteraciones electrocardiográficas (onda p ausente, pobre progresión de onda R). En este caso se documentó bloqueo de rama izquierda.
Objetivo. Describir factores desencadenantes, evolución, abordaje diagnóstico y tratamiento de un caso de síndrome de BRASH con bloqueo de rama izquierda.
Metodología y resultados. Se presenta el caso de mujer de 93 años, en tratamiento con betabloqueadores que presentó síndrome de BRASH desencadenado por cuadro diarreico previo.
Discusión. El síndrome de BRASH es un reto terapéutico porque puede derivar en falla multiorgánica y choque, por lo que se recomienda un abordaje integral (identificar factores desencadenantes, hiperkalemia y cambios electrocardiográficos relacionados; estabilización hemodinámica).
Conclusión. Es importante el adecuado abordaje diagnóstico considerando datos electrocardiográficos no comunes, así como los retos esperados durante su tratamiento (deterioro renal, exacerbación de la hiperkalemia y la consecuente inestabilidad hemodinámica).
Importancia de los principios éticos en la funciones del personal en la subdelegación del seguro social de Guasave
Authors: Urías Rivas Dra. María Oralia 
Published: November 2022

En este proyecto se examinó la importancia de los principios éticos en las funciones del personal en la Subdelegación del Seguro Social de Guasave. Con el objetivo de analizar el comportamiento de los trabajadores sobre la aplicación de la toma de decisiones con razonamiento amplio de forma correcta, procurando alternativas confiables y precisas al decidir actuar con valores morales en el sector institucional público dedicado a la salud. El estudio se basa en consultar información documental y de campo con el método mixto, en donde se encuestó a 24 empleados administrativos eligiéndolos al azar con el muestreo simple. En donde se elaboraron entrevistas estructuradas y cuestionarios que sirvieron de guía para no perder datos que se utilizaron para validar los resultados en el que se encontró que conocen los principios éticos, pero no los practican, ya que realizan las actividades mediante el conformismo, conveniencia, actitud y facilidad de cada persona. Es por ello que se concluyó establecer estrategias para diseñar cursos periódicos, elaborar folletos, fijar reglas y política en base a la cultura y creencia de la organización con la finalidad de mejorar la imagen.