bluuebunny/crossref_metadata_2025_split huggingface dataset:
TERRITORIALIZAÇÃO E GOVERNANÇA TERRITORIAL NO MERCADO DE MATERIAIS RECICLÁVEIS DA BAHIA: ASPECTOS TEÓRICOS PARA UM CENÁRIO EMPÍRICO
Authors: Cassiano de Araujo Cristiano 
Published: June 2022

O presente artigo objetiva analisar os aspectos que concernem à produção e comercialização de materiais recicláveis da Rede Cata Bahia - uma Rede de Reciclagem composta por vinte cooperativas presentes em nove cidades de diferentes regiões do estado da Bahia - à luz de dois elementos analíticos e metodológicos da Geografia: o primeiro refere-se ao fato que, ao se distribuir no território baiano, em diferentes regiões do estado, por meio da espacialização das cooperativas que dela fazem parte, a Rede promove, primeiramente, um processo de Territorialização desta atividade, distribuindo e organizando as cooperativas numa perspectiva territorial; esta dinâmica política e econômica viabiliza um modelo de Governança Territorial, ao horizontalizar e compartilhar as decisões tomadas no ínterim desta Rede pelos cooperados no que tange à procura pelos melhores mercados para a venda destes materiais junto a outros agentes e atores influentes na produção do território (indústrias, sucateiros etc.). A discussão em si justifica-se em face da importância que este setor da economia representa hoje em dia, transpassando do simples ato de comercializar esses materiais ao fato de que parte dos materiais recicláveis são utilizados na linha produtiva de algumas indústrias, substituindo as matérias-primas naturais. Dessa forma, debate-se de que forma a dinâmica econômica e socioespacial da Rede Cata Bahia, por intermédio dos processos de Territorialização e Governança Territorial, concluindo que ambas podem fazer do setor de reciclagem mais um componente para o fortalecimento de uma Política Territorial e de Desenvolvimento no estado da Bahia.
NATUREZA E TÉCNICA NA RAIA SC-RS: CYBORGS HIDRELÉTRICOS E RESSIGNIFICAÇÃO DE PAISAGENS
Authors: Bosa Eliezer , De Souza Reginaldo José 
Published: June 2022

A natureza é contextualizada no campo das intencionalidades, artificializada e produzida. Esta nova natureza não só é resultado de milhões de anos de evolução e intemperismos, ela recebe também uma forte carga de técnica, mudando sua essência, fundindo-se com as realizações humanas. Desta fusão entre sociedade/natureza, materializa-se no espaço o retrato da nossa sociedade. A materialização desta nova natureza deixa marcas visíveis na paisagem: objetos híbridos de socionatureza. Talvez, os contextos paisagísticos de áreas com empreendimentos hidrelétricos sejam boas representações desta nova natureza. Estas obras causam impactos de ordem social, psicológica e ecológica, mudando paisagens e as percepções de indivíduos. Assim, este trabalho teve como objetivo central compreender os desdobramentos do conceito de natureza no mundo contemporâneo, considerando a ubiquidade do fenômeno técnico e a criação de novos agentes da produção espacial: os agentes cyborgs. No âmbito desta nova categoria de agentes da produção do espaço geográfico, organizou-se a reflexão com enfoque no exemplo dos empreendimentos hidrelétricos localizados na Raia Santa Catarina-Rio Grande do Sul, especificamente as Usinas Barra Grande e Itá. Partiu-se do pressuposto de que a metáfora do cyborg pretende ser um símbolo da superação das fraquezas humanas e do caos da natureza, algo “pós-social” e “pós-natural”. Porém, as grandes obras de engenharia também estão sujeitas às imprevisibilidades de toda ordem. Com isto, chegou-se a três considerações importantes para colaborar com a análise geográfica das questões ambientais: i) a economia capitalista é responsável pela disseminação de um paradigma de “natureza-criatura”, em detrimento de um paradigma de “natureza-criação”; ii) nos dias atuais, isto refina tanto o fenômeno técnico, que faz com que a ideia de controle da natureza seja encarada como uma verdade e não uma ilusão; iii) a sociedade está despreparada para arcar com as consequências de que seus grandes cyborgs são, assim como ela, disfuncionais.
A CONSTRUÇÃO DE MODALIDADES DE GOVERNANÇA NA DINÂMICA CONTEMPORÂNEA DO TERRITÓRIO NO ESTADO DO MARANHÃO
Authors: Carvalho Fernanda Cunha de , Pires Elson Luciano Silva 
Published: June 2022

alterados, quando consideradas as formas de governança vinculadas aos territórios. A governança ganha um formato territorial que deve considerar uma coordenação vertical e horizontal articulada e voltada para a ação pública e regulação dos processos socioeconômicos e territoriais, contando com uma participação ativa de múltiplos atores. A observação do Estado do Maranhão apresenta-se com o objetivo de compreender como as modalidades de governança tem se manifestado. A metodologia da pesquisa se deu mediante a leitura de referenciais bibliográficos, documentais e cartográficos, bem como através de visitas em órgãos governamentais que se situam à frente das modalidades de governança no contexto maranhense. O artigo indica que a existência de práticas de governança no contexto local ainda são frágeis e não têm alcançado sua dimensão operacional, destacando que o processo de coordenação ainda permanece centralizado em algumas localidades e atores e que as modalidades de governança têm uma base de consolidação governamental. Contudo, podem ser consideradas pelas tipologias de Governança Estatal-Privada e de Governança Pública-Tripartite.
Pendidikan Anak Usia Dini dalam Keluarga di Era Disrupsi Berdasarkan 2 Timotius 3:15-17
Authors: Meilani Meilani , Fernando Andreas 
Published: June 2022

Abstract: Technological developments that occur massively have made children grow up in a different pattern from the previous generation who lived in the past. Children from an early age have been acquainted with technology that affects their cognitive development and behavior patterns. The purpose of writing this article is to find out the theory and practice of family education that is appropriate for early childhood in facing challenges in this era of disruption by looking at the content of the context of 2 Timothy 3:15-17. The method used in this research is descriptive qualitative. The data collection technique was by examining the theological descriptions of 2 Timothy 3:15-17 from the Bible, as well as digging up information from various literatures, in the form of journals, commentaries, and books on early childhood development and the era of disruption. Through this research, it was found that based on 2 Timothy 3:15-17, the best way to educate children in today's families is to educate them as early as possible to study and explore the contents of the Holy Scriptures so that children have wisdom in overcoming problems and challenges, especially those that can shake faith as a result. the impact of current technological advances.

Abstrak: Perkembangan teknologi yang terjadi secara pesat saat ini telah membuat anak-anak bertumbuh dengan pola yang berbeda dari generasi yang hidup pada masa sebelumnya. Anak sejak usia dini telah berkenalan dengan teknologi yang memengaruhi perkembangan kognitif dan pola tingkah laku mereka. Tujuan dari penulisan artikel ini adalah untuk mengetahui teori dan praktik pendidikan keluarga yang sesuai bagi anak usia dini dalam menghadapi tantangan di era disrupsi ini dengan melihat isi konteks dari 2 Timotius 3:15-17. Metode yang digunakan dalam penelitian ini adalah kualitatif deskriptif. Teknik pengumpulan data dengan mengkaji uraian teologis dari 2 Timotius 3:15-17 dari Alkitab, juga menggali informasi dari berbagai literatur, berupa jurnal, buku-buku tafsiran, dan buku-buku mengenai perkembangan anak usia dini dan era disrupsi. Melalui penelitian ini ditemukan bahwa berdasarkan 2 Timotius 3:15-17, cara terbaik pendidikan anak dalam keluarga masa kini adalah dengan sedini mungkin mendidik mereka untuk mempelajari dan mendalami isi Kitab Suci sehingga anak memiliki hikmat dalam mengatasi masalah dan tantangan terutama yang dapat menggoyahkan iman akibat pengaruh kemajuan teknologi saat ini.
Non-Invasive Approach for Glucose Detection in Urine Quality Using Its Image Analysis
Authors: Yudhana Anton , Yusrina Sabila Liya , Cahya Subrata Arsyad , Helda Pratama Hendriana , Syahrul Akbar Muhammad 
Published: June 2022

Human health can be detected through urine content, where metabolic waste in the body is excreted through urination. Glucose in the urine is caused by high levels of glucose in the blood, which can cause poor kidney function. This study aims to detect glucose in urine using non-invasive image analysis. The three measurement parameters in this research consist of Hue (H) is the color portion of the model that is expressed as a number from 0°C to 360, saturation (S) is the amount of gray in a particular color from 0% to 100%, and value/brightness (V) is the intensity of the color from 0% to 100%. Reagent strips for urinalysis with 10 variables are applied in this research, including glucose, bilirubin, ketone, specific gravity, blood, pH, protein, urobilinogen, nitrite, and leukocytes. All reading data from the system is sent to the monitor layer, which uses the python platform with the additional library Open-cv. The results obtained that the urine color is getting dimmer with the addition of 1 g of glucose in each test. This study was able to detect glucose in urine using image analysis.
Benign Prostatic Hyperplasia: Epidemiology, Pathophysiology, and Clinical Manifestations
Authors: Irene Pascual Mathey Luz 
Published: June 2022

The prostate secretes 20% of the seminal fluid. One of its main pathologies is benign prostatic hyperplasia (BPH), the most common benign disease in older men. It has an 8–10% prevalence in men 40 years of age and older, increasing to more than 90% in men over 90 years, with lower urinary tract symptoms being one of its main complications. Although the etiology of BPH is not still fully known, testosterone and estradiol have shown a permissive role. Likewise, other factors have emerged, such as inflammation, growth factors, and prolactin, which influence the development of BPH. These factors act through binding to specific receptors, intervening in BPH and prostate cancer development. Existing treatments significantly reduce clinical symptoms, including lower urinary tract symptoms. However, it is a nonpreventable disease; some factors can reduce its incidence: diet, physical activity, and moderate consumption of alcohol and tobacco, some of which have been proposed to have a protective role. Therefore, this chapter aims to update the preclinical and clinical evidence on the etiology of this disease, briefly describing the epidemiology, clinical manifestations, and therapeutic and preventive modalities in managing BPH.
Alteration of the Cultural, Religious and Architectural Heritage from Lăpuș Land, in the Context of Climate Change
Authors: Țenter Ancuța , Burghele Bety , Cotețiu Marin , Rauca Adrian , Schroder Verginica , Vasile Pop Florin , Săsăran Patricia 
Published: June 2022

The architectural heritage is considered the most important category of cultural heritage; therefore, it requires special attention in the current state of climate change. The heritage presented in this chapter includes a total of 26 wooden churches located in Lăpuș Land, framed by UNESCO to the national heritage A and B category. Built on the present grounds or relocated, these are between 200 and 400 years old. Their degradation/alteration has been imminent over the decades due to aging and the socio-political conditions of the times. Alteration is a common notion in relation to the passage of time. The changes in environmental physical parameters, however, raise issues of sustainability of the buildings due to degradation. This paper wants to bring to the readers’ attention the importance and vulnerability of murals in wooden churches of Lăpuș County, which are an invaluable treasure, in terms of constructions, objects and traditions that require a civic responsibility for future generations in these difficult geopolitical conditions overlapping climate change.
Anthropometrics in Predicting Cardiovascular Disease Risk: Our Research Work Mathematically Demonstrates that Cardiovascular Sciences Were Always Confused for a Long Time
Authors: Martin Castellanos Angel 
Published: June 2022

Cardiovascular diseases (CVDS) mainly heart disease and stroke are the leading causes of death globaly. Obesity is a major risk factor for myocardial infarction (MI) and CVD. However, how to measure CVD risk with simple baseline anthropometric characteristics? Besides, association of anthropometrics and CVD may present effects of bias, and in evaluating risk, the lack of balance between simple measurements will be particularly prone to the generation of false-positive results. The purpose of this paper is to provide the key concepts for demonstrating association biases for metrics taken from multiple large-scale studies worldwide. Epidemiologically, waist-to-hip ratio (WHR) is a confounding variable with respect to waist circumference (WC) and waist-to-height ratio (WHtR). This is due to different imbalances between hip circumference (HC)-WC and HC-height, respectively, occurring in a protective overestimation for HC concerning WC and height. Similarly, WC may be a confounding variable with respect to WHtR due to an imbalance in WC-height: This occurs if, and only if, the mean WC > height/2 (WHtR risk cut-off >0.5). This, therefore, overestimates risk in tallest people and lead to underestimations in the shortest people. Anthropometrically, only WHtR is the only measure that is directly associated to a relative risk volume and yields no biases, and it should therefore be the metric used to compare the anthropometrically-measured causal risk.
Retrospective Evaluation of Inborn Errors of Metabolisms in the Level III Neonatal Intensive Care Unit
Authors: DEGER Ibrahim , TAŞ Ibrahim , SAMANCI Serhat 
Published: June 2022

Objective: Inborn errors of metabolisms (IEMs) are a heterogeneous group of disorders that can occur as a result of inherited or spontaneous mutations, are rare when considered alone, but have many diseases as a group. Although they are generally thought of as diseases of the neonatal period, 50% of these also occur outside the neonatal period, and some are not diagnosed until adulthood. The aim of this study is to examine the frequency, clinical and laboratory features of inborn errors of metabolism in the neonatal period.
Methods: The results of 60 patients who were diagnosed with IEMs as a result of the study, out of 1400 patients who were followed up and treated in the Children's Hospital Neonatal Intensive Care Unit between January 2018 and December 2020, were evaluated.
Results: In this study, it consisted of 60 cases, 30 (%50) of which were girls and 30 (%50) were boys (50%). The median age of the patients included in the study was 3 (1-25) days at admission, median weight was 3100 (1000-4000) g, and gestational week was found to be median 39 (27-40) weeks at admission. The most common complaints were feeding difficulty 43(72%), tachypnea 27 (45%) and vomiting 5 (8.3%). The most common laboratory findings were metabolic acidosis 39 (65%) and 36 (60%) hypoglycemia. There was a history of consanguinity in 46 (76.6%) cases, and a history of sibling death in 30 (50%). The mother had a history of abortion in 5 (8.3%) patients who did not have a history of sibling death. The most common diagnoses were Urea cycle disorder 13 (21.7%), organic acidemia 12 (20%), galactosemia 10 (16.7%) and amino acid metabolism disorders 9 (15%).
Conclusion: Inborn errors of metabolisms, which are a group of diseases that can occur in different spectrums with clinical, biochemical and genetic heterogeneity, should be kept in mind especially in regions where consanguineous marriages are high. In cases such as metabolic acidosis, which presents with nonspecific symptoms such as malnutrition, tachypnea and jaundice in the neonatal period and cannot be explained in laboratory examinations, care should be taken and they should be referred to centers for further investigation.
Clinical Testing for Tumor Cell-Free DNA: College of American Pathologists Proficiency Programs Reveal Practice Trends
Authors: Devereaux Kelly A. , Souers Rhona J. , Merker Jason D. , Lindeman Neal I. , Graham Rondell P. , Hameed Meera R. , Vasalos Patricia , Moncur Joel T. , Lockwood Christina M. , Xian Rena R. 
Published: June 2022

Context.—Clinical testing for tumor cell-free DNA (cfDNA) has evolved rapidly, but no practice guidelines exist.Objective.—To summarize cfDNA laboratory practices based on self-reporting and assess preanalytical, analytical, and postanalytical trends that may influence the quality, accuracy, and consistency of cfDNA testing.Design.—Data were derived from the College of American Pathologists cfDNA proficiency testing program submitted by 101 participating laboratories from 2018 to 2019.Results.—Most laboratories performing clinical circulating tumor DNA testing are commercial/nonhospital (71.2%; 72 of 101) and international (77.2%; 78 of 101) laboratories. Commercial laboratories had higher monthly test volumes than hospital-based laboratories (median, 36 versus 7–8) and tended to have larger gene panels (median, 50 versus 11 genes) when panel-based testing was offered. The main clinical indications include therapy selection and treatment/disease monitoring. Plasma is the most commonly accepted specimen, which is predominantly collected in cell-stabilizing tubes. Equal proportions of laboratories use next-generation sequencing (NGS) and non-NGS methods to assess key genes, including EGFR, BRAF, KRAS, NRAS, and IDH1. Most laboratories reported a lower limit of detection (LLOD) of 0.5%, variant allele frequency or less, which did not differ by method, NGS or non-NGS, except for EGFR. Sixty-five percent (17 of 26) of laboratories using the US Food and Drug Administration (FDA)-approved non-NGS EGFR assay report analytical sensitivities higher than 0.5%, as compared to 15% (16 of 104) of laboratories using an alternative NGS or non-NGS method. There is also a wider range in LLODs obtained for the FDA-approved EGFR assay than nonapproved assays.Conclusions.—These results highlight emerging practice trends and serve as a foundation to initiate future practice recommendations.
Sailing in Waves: A Numerical Method for Analysis of Seakeeping Performance and Dynamic Behavior of a Wind Powered Ship
Authors: Kjellberg Martin , Gerhardt Frederik , Werner Sofia 
Published: June 2022

Before the background of the International Maritime Organization’s 2050 emission reduction targets, the largest sailing ship in the world is currently being developed in Sweden This wind powered car carrier, called Oceanbird, will have four 80-metre-high wing sails targeting CO2 savings in the order of 90%.
The prediction and analysis of the seakeeping performance of such a ship is of importance, not only in terms of sailing dynamics, but also when it comes to the structural design of the rig.
To this end, a numerical method for predicting a ship’s motions and loads in its rigid wing sails is described in this paper and a demonstration of how the method can be used to obtain such loads is presented.
The numerical method is based on an unsteady 3D fully nonlinear potential flow hydrodynamic model coupled with a hybrid 2D RANS/3D lifting-line aerodynamic model. Simulations in a seaway with short-crested irregular waves and corresponding wind conditions are conducted, resulting in time histories of the aerodynamic and inertial forces acting on the rig.
Possible applications of the method include fatigue analysis of the wing sails, where the accumulated fatigue damage over the lifespan of the rig structure depends on the sum of aerodynamic forces and motion induced inertial forces. Other potential applications include sail dynamics, parametric roll, sheeting strategies and appendage configuration studies.
BARRERAS Y OPORTUNIDADES PARA LA INSERCIÓN LABORAL DE LAS PERSONAS CON DISCAPACIDAD EN EL SECTOR TURÍSTICO DE LA PROVINCIA DE ALICANTE
Authors: Huete Nieves Raquel , García-Ramos Agustín 
Published: June 2022

Based on the inclusive tourism theoretical assumptions, this study identifies the barriers and opportunities for the professional inclusion of people with disabilities in the tourism sector in Alicante province (Spain). For this purpose, 34 semi-structured interviews to different tourism stakeholders are analysed from a qualitative methodology. The results reveal the existence of prejudices and misinformation but also, the opportunities that can be useful in creating business strategies and public policies.
Partiendo de los presupuestos teóricos del turismo inclusivo, este estudio identifica las barreras y las oportunidades para la inserción laboral de las personas con discapacidad en el sector turístico de la provincia de Alicante (España). A tal fin, se recurre a una metodología cualitativa, con datos generados a partir de 34 entrevistas semiestructuradas realizadas a distintos colectivos del sector. Los resultados revelan la existencia de prejuicios y desinformación, pero también de oportunidades, que pueden contribuir a mejorar el diseño de estrategias empresariales y políticas públicas.
Impact of the COVID-19 pandemic on breast cancer screening indicators in a Spanish population-based program: a cohort study
Authors: Bosch Guillermo , Posso Margarita , Louro Javier , Roman Marta , Porta Miquel , Castells Xavier , Macià Francesc 
Published: June 2022

Background:To assess the effect of the COVID-19 pandemic on performance indicators in the population-based breast cancer screening program of Parc de Salut Mar (PSMAR), Barcelona, Spain.Methods:We conducted a before-and-after, study to evaluate participation, recall, false positives, the cancer detection rate, and cancer characteristics in our screening population from March 2020 to March 2021 compared with the four previous rounds (2012–2019). Using multilevel logistic regression models, we estimated the adjusted odds ratios (aORs) of each of the performance indicators for the COVID-19 period, controlling by type of screening (prevalent or incident), socioeconomic index, family history of breast cancer, and menopausal status. We analyzed 144,779 invitations from 47,571women.Results:During the COVID-19 period, the odds of participation were lower in first-time invitees (aOR = 0.90 [95% CI = 0.84–0.96]) and in those who had previously participated regularly and irregularly (aOR = 0.63 [95% CI = 0.59–0.67] and aOR = 0.95 [95% CI = 0.86–1.05], respectively). Participation showed a modest increase in women not attending any of the previous rounds (aOR = 1.10 [95% CI = 1.01–1.20]). The recall rate decreased in both prevalent and incident screening (aOR = 0.74 [95% CI = 0.56–0.99] and aOR = 0.80 [95% CI = 0.68–0.95], respectively). False positives also decreased in both groups (prevalent aOR = 0.92 [95% CI = 0.66–1.28] and incident aOR = 0.72 [95% CI = 0.59–0.88]). No significant differences were observed in compliance with recall (OR = 1.26, 95% CI = 0.76–2.23), cancer detection rate (aOR = 0.91 [95% CI = 0.69–1.18]), or cancer stages.Conclusions:The COVID-19 pandemic negatively affected screening attendance, especially in previous participants and newcomers. We found a reduction in recall and false positives and no marked differences in cancer detection, indicating the robustness of the program. There is a need for further evaluations of interval cancers and potential diagnostic delays.Funding:This study has received funding by grants PI19/00007 and PI21/00058, funded by Instituto de Salud Carlos III (ISCIII) and cofunded by the European Union and Grant RD21/0016/0020 funded by Instituto de Salud Carlos III and by the European Union NextGenerationEU, Mecanismo para la Recuperación y la Resiliencia (MRR).