bluuebunny/crossref_metadata_2025_split huggingface dataset:
The magnitude of mental distress and associated factors among a school of medicine and college of health sciences students at Debre Markos University, 2021
Authors: Amlak Baye Tsegaye , Bitew Mezinew Sintayehu , Getnet Asmamaw , Yitayew Fentahun Minwuyelet , Terefe Tamene Fetene , Tarekegn Tadesse Tsehay , Mihret Asmare Getie , Geleta Omega Tolessa , Alemu Gebrie Getu , GebreEyesus Fisha Alebel , Tsegaye Dejen 
Published: September 2022

Introduction
Mental distress is a collection of mental health abnormalities characterized by symptoms of anxiety, depression, insomnia, fatigue, irritability, forgetfulness, difficulty in concentrating, and somatic symptoms. It affects society as a whole and no group is immune to mental distress; however, students have a significantly high level of mental distress than their community peers. The study is aimed to assess the magnitude of mental distress and associated factors among a school of medicine and college of health sciences students.

Objective
To assess the magnitude of mental distress and associated factors among a school of medicine and college of health sciences students at Debre Markos University, 2021.

Methods
Institution-based cross-sectional study design was employed from March 15–29, 2021. A simple random sampling technique was used to select 475 study participants. A binary logistic regression model was used to identify factors associated with mental distress. Variables with a p-value less than 0.25 in the bivariable analysis were entered into multivariable logistic regression analysis and a P-Value of less than 0.05 was considered as having a statistically significant association.

Result
The magnitude of mental distress among students was found to be 35.4%, 95%CI (31%, 40%). Female sex [AOR = 1.95; 95%CI (1.24–3.06)], financial distress[AOR = 1.64; 95%CI (1.062.54)], feeling of insecurity [AOR = 2.49; 95% CI (1.13–3.54)], lack of interest to department [AOR = 2.00; 95%CI (1.75–4.36)] and cumulative grade point average less than expected [AOR = 2.63; 95%CI (1.59–4.37)]were significant variables with mental distress.

Conclusion
The magnitude of mental distress was high. Sex, financial distress, feeling of insecurity, lack of interest in the department, and cumulative grade point average less than expected were significant variables with mental distress, so special attention on mental health promotion is required from policymakers, college officials, parents, and other Non-Governmental organizations.
A High‐Value Agriculture‐Based Strategy for Reducing Poverty in Sub‐Saharan Africa
Authors: Yeh Stuart S. 
Published: September 2022

AbstractAbstractThe World Bank and IMF emphasize privatization and economic liberalization as a strategy to reduce poverty in developing nations. However, results have been disappointing. This article offers an alternative, in the form of a practical strategy for improving economic growth and reducing poverty in sub‐Saharan Africa that flows directly from an analysis of why Africans remain poor. This strategy aims to raise rural incomes and stimulate aggregate demand and output through the widespread introduction of rainwater harvesting, micro drip irrigation systems, and systems of agricultural cooperatives to cultivate and market high‐value agricultural products. The article concludes that the income generated in the rural sector would be multiplied by increases in income from induced consumption expenditures. The overall impact would be substantial and could greatly improve economic growth rates in sub‐Saharan Africa. The article discusses issues that must be addressed to realize these benefits fully, but concludes that an agriculture‐based poverty‐reduction strategy may potentially be much more effective than orthodox World Bank and IMF strategies.
Exploring the Economic Determinants of Immigration Attitudes
Authors: Miller Beth 
Published: September 2022

AbstractAbstractThis study explores the economic determinants of attitudes toward immigration across fortyseven countries. The extant research addressing public opinion on immigration tends to concentrate on Anglo attitudes toward immigrants in the United States or attitudes toward immigrants in Western Europe. Thus, empirical evidence currently draws from a limited pool including advanced industrial democracies. To more accurately and completely generalize statements regarding support for economic theories of self‐interest in regards to immigration, cross‐national research outside of the advanced industrial arena is necessary. Merging individual‐level survey data from Pew's Global Attitudes Project with country‐level economic data, the study finds that self‐assessed poverty plays a significant role in structuring immigration attitudes independent of the effect of objective measures of economic status (education, employment, and income). Further, national economic conditions also play a role in shaping immigration attitudes across countries.
Book Review: Global Child Poverty and Well‐Being: Measurement, Concepts, Policy and Action” by Alberto Minujin and Shallen Nandy
Authors: Beard Virginia Parish 
Published: September 2022

AbstractAbstractOf the countless people around the world enduring deprivation and tremendous suffering from poverty and malnutrition, hundreds of millions are children. But research on poverty and development has only relatively recently begun to focus on this aspect of global poverty. Featuring contributions from leading researchers, this book examines how child poverty and well‐being are conceptualized, defined, and measured and presents regional and national studies of child poverty from around the world. Global Child Poverty and Well‐Being is an urgent call to arms for researchers and policymakers to confront one of the world's great ongoing tragedies.
Person Centered Medicine
Authors: Snaedal Jon 
Published: September 2022

AbstractPerson centered medicine has emerged as a response to the organ specific, technical and fragmented medical treatment and care that has evolved during the last century in health care systems worldwide. Nevertheless, person centered medicine is not a new concept, as it is rooted in ancient medicine, exemplified by the medical culture of the ancient Greeks. The main components of Person Centered Medicine described here are the cornerstone for successful medical treatment and care. The physician needs to use his communicative skills for this purpose, adhere to attentive, empathic listening, be aware of the cultural, social and educational background of the patient and understand the expectations of the patient for the therapy ahead. He must place the narrative of the patient at the center of clinical evaluation. For this to be possible, the physician needs to have the necessary professional competence and to adhere to the basic ethical principles of medicine. He needs to collaborate not only with the patient, and in some instances with his or her family, but also with other health care workers, whether in a close therapeutic team or with individual professionals. He needs to critically evaluate evidence‐based medicine that is most often presented by various, complicated statistics and to adapt the results of research to his patients in a person centered fashion. For this to be possible, the curricula of Medical Faculties, as well as to mainstream, continuous professional development programs, needs to include the components of Person Centered Medicine.
A Case Study in Translating Medical Evidence into Mobile Decision Support
Authors: Sheets Lincoln 
Published: September 2022

AbstractBackground: Combination oral contraceptives are prescribed 10 million times a year in the United States alone. Prescribers have more than 70 oral‐contraceptive choices, but individual women's medical conditions may make some contraceptives inappropriate or dangerous. Traditional sources of prescribing information are impractical at the point of care. Mobile apps are revolutionizing clinical workflow, but none have been deployed for oral‐contraceptive selection. Objective/Purpose: to design of an evidence‐based interactive tool for selecting oral contraceptives, as a model for dissemination of clinical practice guidelines to clinical settings via mobile applications. Methods: I indexed the practice guidelines for hormonal contraception from the World Health Organization and the American Congress of Obstetricians and Gynecologists, and expert recommendations from two contraceptive textbooks. I gathered the rules into IF‐THEN use cases, annotated with evidence quality and prioritized by likelihood and importance, and classified contraceptive choices into specific recommendation groups. Results: The sources yielded 32 guidelines and 24 expert recommendations using a total of 73 data elements, mostly TRUE/FALSE choices or numeric values. Organizing these into 22 use cases evaluating one to eight data elements each, few enough to fit on a smartphone screen, permits the entire questionnaire to be navigated in 22 or fewer screens. Discussion/Conclusions: Handheld clinical applications can facilitate evidence‐based medicine, and reduce medical errors, by moving the best available medical knowledge from laborintensive traditional resources to prescribers' fingertips. They may create privacy and data‐security risks, but limiting apps to anonymous single‐use queries obviates these. Potential enhancements include additional object‐oriented treatment domains, automatically updating rules engines using the Guideline Elements Model, and allowing user communities to add rules.
Inequalities in Health: Realities, Efforts and Way Forward
Authors: Paudel Deepak , Abera Muluemebet , Kyeyune Rachel , Solis‐Soto Maria Teresa , Lohani Ashish , Wandiga Steve , Nji Akindeh , Froschel Guenter 
Published: September 2022

AbstractInequalities in health are not a new phenomenon but a challenge for public health practitioners around the globe. Considering the importance of the topic, a one day symposium was organized targeting public health, medical and social science professionals and students in Munich, Germany on March 17th, 2012. The paper documents major highlights of the event and summarizes the importance of such events in sensitizing current and future professionals on different aspects of health inequality and in drawing their attention into the topic.
Enhanced design of PID controller and noise filter for second order stable and unstable processes with time delay
Authors: Rahul Banda Sai , Ajmeri Moina 
Published: September 2022

Abstract
In this work, a PID controller along with a noise filter is designed using direct synthesis method for second order stable and unstable processes with time delay. Proposed method involves a single design parameter λ whose value need to be adjusted such that a desired balance between performance and robustness of the system is achieved. Guidelines to select suitable values of λ based on the maximum sensitivity values are provided. Various computer simulations are performed in presence of measurement noise on stable, unstable, integrating and double integrating dynamic systems to illustrate the advantages of suggested control method over some contemporary techniques. Performance measures (integral absolute error and integral squared error) and robustness measures such as maximum sensitivity (M
s), complimentary sensitivity (M
t) are calculated for the quantitative performance evaluation of the proposed tuning strategy. The suggested tuning algorithm is simple and it yields improved closed loop response compared to some reported methods, satisfactory robustness and smooth control action in presence of noise.
Stable 𝔸1-connectivity over a base
Authors: Druzhinin Anderi Eduardovich 
Published: September 2022

AbstractMorel’s stable connectivity theorem states the vanishing of the sheaves of the negative motivic homotopy groupsπ¯is⁢(Y){\underline{\pi}^{s}_{i}(Y)}andπ¯i+j,js⁢(Y){\underline{\pi}^{s}_{i+j,j}(Y)},i<0{i<0}, in the stable motivic homotopy categories𝐒𝐇S1⁢(k){\mathbf{SH}^{S^{1}}(k)}and𝐒𝐇⁢(k){\mathbf{SH}(k)}for an arbitrary smooth schemeYover a fieldk. Originally the same property was conjectured in the relative case over a base schemeS. In view of Ayoub’s conterexamples the modified version of the conjecture states the vanishing of stable motivic homotopy groupsπ¯is⁢(Y){\underline{\pi}^{s}_{i}(Y)}(andπ¯i+j,js⁢(Y){\underline{\pi}^{s}_{i+j,j}(Y)}) fori<-d{i<-d}, whered=dim⁡S{d=\dim S}is the Krull dimension. The latter version of the conjecture is proven over noetherian domains of finite Krull dimension under the assumption that residue fields of the base scheme are infinite. This is the result by J. Schmidt and F. Strunk for Dedekind schemes case, and the result by N. Deshmukh, A. Hogadi, G. Kulkarni and S. Yadavand for the case of noetherian domains of an arbitrary dimension. In the article, we prove the result for any locally noetharian base scheme of finite Krull dimension without the assumption on the residue fields, in particular for𝐒𝐇S1⁢(ℤ){\mathbf{SH}^{S^{1}}(\mathbb{Z})}and𝐒𝐇⁢(ℤ){\mathbf{SH}(\mathbb{Z})}. In the appendix, we modify the arguments used for the main result to obtain the independent proof of Gabber’s Presentation Lemma over finite fields.
Kantian Constructivism and Kantian Constitutivism: Some Reflections
Authors: Reath Andrews 
Published: September 2022

AbstractIs moral constructivism an account of the basis of the content of morality or of its authority? In fact, different writers have understood constructivism to be addressing different issues. In this paper I argue that Kant should be understood as a constructivist about the content of morality – or better about a limited set of general substantive principles – and as a constititutivist about its authority. After some general remarks in Section 1 about contemporary discussions of constructivism, in Section 2 I discuss Rawls’s understanding of Kant’s constructivism; Rawls takes Kantian constructivism to be a view about the content of morality. In Section 3, I give an overview of Kant’s moral conception as constructivist about the content of morality and as constitutivist about its authority. In Section 4 I address a worry whether certain features of Kant’s constitutivism rest his constructivism on a realist foundation, arguing that they do not.
lncRNA NORAD promotes lung cancer progression by competitively binding to miR-28-3p with E2F2
Authors: Mao Wenjun , Wang Shengfei , Chen Ruo , He Yijun , Lu Rongguo , Zheng Mingfeng 
Published: September 2022

Abstract
Lung cancer (LC) is a prevailing primary tumor in the lung. lncRNA non-coding RNA activated by DNA damage (NORAD) is a popular target in human cancers. This experiment is designed to probe the mechanism of lncRNA in LC progression. NORAD expression in normal lung epithelial cells and LC cells was examined and then silenced to assess its effect on LC cell proliferation, invasion, and migration. Subcellular localization of NORAD was analyzed through online databases and then corroborated by fractionation of nuclear and cytoplasmic RNA assay. The target binding relations between NORAD and miR-28-3p and between miR-28-3p and E2F2 were verified. Eventually, LC cells with NORAD silencing were transfected with miR-28-3p inhibitor or pcDNA3.1-E2F2 to measure LC cell proliferation, invasion, and migration. NORAD was overexpressed in LC cells and NORAD knockout led to suppressed LC cell proliferation, invasion, and migration. Besides, NORAD targeted miR-28-3p and miR-28-3p targeted E2F2 transcription. Inhibiting miR-28-3p or overexpressing E2F2 could both annul the inhibitory role of si-NORAD in LC cell proliferation, invasion, and migration. Generally, our findings demonstrated that NORAD competitively bound to miR-28-3p with E2F2, to promote LC cell progression.
Does real interest rate parity really work? Historical evidence from a discrete wavelet perspective
Authors: Ghaemi Asl Mahdi , Canarella Giorgio , Miller Stephen M. , Tavakkoli Hamid Reza 
Published: September 2022

Abstract
We test for real interest rate parity using data from six European countries (France, Germany, Italy, the Netherlands, Spain, and the United Kingdom), Japan, and the United States over a period of more than two centuries. Our contribution is threefold. First, we implement a wavelet-based analysis, which examines both frequency and time information contained in a time series. Second, we employ the United States, the United Kingdom, and Germany as alternative base countries in the wavelet regressions to ascertain the sensitivity of the results to the choice of the base country. Third, we test the real interest rate parity over the entire period (1800–2018) and for several non-contiguous subperiods that hold historical significance and relative importance. Three subperiods link to the three globalization waves (1870–1914, 1944–1971, and 1989–2018), and four subperiods connect to the exchange rate regimes. The wavelet-based results suggest that the validity of the real interest rate parity is scale-dependent. The specific evidence in most cases supports the parity at lower frequencies but not at higher frequencies, which is consistent with the idea that the purchasing power parity and uncovered interest parity, the two main ingredients of the real interest rate parity, are mostly valid in the long run.
Lire et écrire en réseau : exemple d’une séquence didactique en français au primaire en appui au développement des compétences globales et numériques
Authors: Nadeau-Tremblay Sophie , Allaire Stéphane 
Published: September 2022

Depuis plus de 20 ans, l’initiative École en réseau (ÉER) déploie le travail collaboratif intra et interclasses au primaire et au secondaire partout au Québec (Allaire et Laferrière, 2013 ; Laferrière et al., 2006). Des enseignants engagés y développent des projets éducatifs novateurs pour favoriser l’apprentissage et l’engagement des élèves ainsi que leur propre développement professionnel (Allaire et al., 2009). Après un bref historique de l’initiative ÉER, l’article présente une séquence d’activités interclasses sous l’angle du développement des compétences à « Lire, Écrire et Apprécier des œuvres littéraires ». L’écriture collaborative constitue un levier reliant le cadre de référence des compétences globales (Conseil des ministres de l’Éducation [Canada], 2016) et des dimensions de la compétence numérique (gouvernement du Québec, 2019) dans les milieux éducatifs au primaire, tant chez les élèves que chez les enseignants. À travers des rencontres en visioconférence et des moments d’écriture en classe, seuls et en collaboration, les élèves contribuent à la coélaboration de connaissances d’une communauté d’apprentissage engagée. Des apports et défis sont relevés afin de soutenir la mise en place d’une telle initiative pédagogique.
Neural Representation of Intraoral Olfactory and Gustatory Signals by the Mediodorsal Thalamus in Alert Rats
Authors: Fredericksen Kelly E. , Samuelsen Chad L. 
Published: September 2022

The mediodorsal thalamus is a multimodal region involved in a variety of cognitive behaviors, including olfactory attention, odor discrimination, and the hedonic perception of flavors. Although the mediodorsal thalamus forms connections with principal regions of the olfactory and gustatory networks, its role in processing olfactory and gustatory signals originating from the mouth remains unclear. Here, we recorded single-unit activity in the mediodorsal thalamus of behaving female rats during the intraoral delivery of individual odors, individual tastes, and odor-taste mixtures. Our results are the first to demonstrate that neurons in the mediodorsal thalamus dynamically encode chemosensory signals originating from the mouth. This chemoselective population is broadly tuned, exhibits excited and suppressed responses, and responds to odor-taste mixtures differently than an odor or taste alone. Furthermore, a subset of chemoselective neurons encodes the palatability-related features of tastes and may represent associations between previously experienced odor-taste pairs. Our results further demonstrate the multidimensionality of the mediodorsal thalamus and provide additional evidence of its involvement in processing chemosensory information important for ingestive behaviors.SIGNIFICANCE STATEMENTThe perception of food relies on the concurrent processing of olfactory and gustatory signals originating from the mouth. The mediodorsal thalamus is a higher-order thalamic nucleus involved in a variety of chemosensory-dependent behaviors and connects the olfactory and gustatory cortices with the prefrontal cortex. However, it is unknown how neurons in the mediodorsal thalamus process intraoral chemosensory signals. Using tetrode recordings in alert rats, our results are the first to show that neurons in the mediodorsal thalamus dynamically represent olfactory and gustatory signals from the mouth. Our findings are consistent with the mediodorsal thalamus being a key node between sensory and prefrontal cortical areas for processing chemosensory information underlying ingestive behavior.
Mediation Principles in the Civil Society and Features of Their Application in the Educational Environment of Ukraine
Authors: Sheremet Anzhelika , Blaschuk Tetiana , Ishchuk Serhii 
Published: September 2022

Aim. The main purpose of research presented in this article is to analyse mediation principles as an alternative way of dispute resolution and features of their application in the educational environment of Ukraine. For which purpose it was necessary to perform the following tasks: - the concept and role of mediation principles were studied; - certain types of mediation principles were defined; - the essence and significance of the most important mediation principles were revealed; - and the application of mediation principles in Ukraine was clarified. In Ukraine, civil society institutions have been trying on their own to introduce and promote mediation as a way of alternative dispute resolution. However, systemic problems of access to justice require finding other ways to resolve conflict situations. Mediation becomes especially relevant in the context of COVID-19 coronavirus pandemic, when access to the court system is limited.
Methods. The study is based on the analysis of enacted regulations and their comparison in different countries, as well as information obtained from the study of literature, including works by authors of both legal and other social sciences where mediation is used as a means of compromise, including psychology, medicine, ecology, along with the use of tools and comments specific to the study of law. To study the prospects and effective application of mediation principles in the educational environment, sociological surveys of various participants of the educational process were conducted.
Results. The results of study showed that certain types of mediation principles are applied in different countries taking into account the peculiarities of national legal systems. Notwithstanding, such principles as the rule of law, the principle of equality (equal rights) of the parties, the principle of voluntariness, confidentiality and mediator behaviour (independence and impartiality, trust and justice) are applied in most of the studied national models of mediation, consequently they can be called fundamental. The survey results have revealed the readiness of the educational environment to introduce mediation as a tool for resolving conflicts in the educational environment. In Ukraine, the draft law “On Mediation” defines general principles of mediation; however, the problem is insufficiently clear criteria for disputes that cannot be transferred to mediation. In addition, the principle of the rule of law should be defined as one of the fundamental principles of mediation.
Conclusions. The specifics of the implementation of mediation principles in Ukraine and their correlation with the principles of the judicial process require further research.