bluuebunny/crossref_metadata_2025_split huggingface dataset:
‘Wish to Dream’ Fulfilment: the Motivations for Onward Migration
Authors: Di Cristo Nunzia , Akwei Cynthia 
Published: September 2022

AbstractThis paper explores the individual and group motivations that have encouraged the onward migration of Italian-Pakistanis and Italian-Bangladeshis to the North of England after obtaining Italian citizenship because the reasons for moving again to the current destination are under-researched. It appears that there has been a design-driven form of intentionality in their complex migrations attributable to the influence of European and Italian policies. Gender and ethnic differences among these groups are identified, as well as the level of their integration in the new host country. A qualitative research approach is adopted utilizing six focus group discussions with 48 participants, and the data collected were subjected to thematic analysis. The findings revealed that aspects of education and qualifications, religion, social identity, and culture along with welfare, security, and employment were the motivations for the participants’ onward migration.
Expression of nectin-4 in papillary renal cell carcinoma
Authors: Zschäbitz Stefanie , Mikuteit Marie , Stöhr Christine , Herrmann Edwin , Polifka Iris , Agaimy Abbas , Trojan Lutz , Ströbel Philipp , Becker Frank , Wülfing Christian , Barth Peter , Stöckle Michael , Staehler Michael , Stief Christian , Haferkamp Axel , Hohenfellner Markus , Duensing Stefan , Macher-Göppinger Stephan , Wullich Bernd , Noldus Joachim , Brenner Walburgis , Roos Frederik C. , Walter Bernhard , Otto Wolfgang , Burger Maximilian , Schrader Andres Jan , Hartmann Arndt , Erlmeier Franziska , Steffens Sandra 
Published: September 2022

Abstract
Background
Nectin-4 contributes to tumor proliferation, lymphangiogenesis and angiogenesis in malignant tumors and is an emerging target in tumor therapy. In renal cell carcinoma (RCC) VEGF-directed tyrosine kinase inhibitors and checkpoint inhibitors are currently treatments of choice. Enfortumab vedotin-ejf (EV) is an antibody drug conjugate that targets Nectin-4. The aim of our study was to investigate the expression of Nectin-4 in a large cohort of papillary RCC specimens.

Patients and methods
Specimens were derived from the PANZAR consortium (Erlangen, Heidelberg, Herne, Homburg, Mainz, Mannheim, Marburg, Muenster, LMU Munich, TU Munich, and Regensburg). Clinical data and tissue samples from n = 190 and n = 107 patients with type 1 and 2 pRCC, respectively, were available. Expression of Nectin-4 was determined by immunohistochemistry (IHC).

Results
In total, Nectin-4 staining was moderately or strongly positive in of 92 (48.4%) of type 1 and 39 (36.4%) type 2 of pRCC cases. No associations between Nectin-4 expression and age at diagnosis, gender, grading, and TNM stage was found. 5 year overall survival rate was not statistically different in patients with Nectin-4 negative versus Nectin-4 positive tumors for the overall cohort and the pRCC type 2 subgroup, but higher in patient with Nectin-4 positive pRCC type 1 tumors compared to Nectin-4 negative tumors (81.3% vs. 67.8%, p = 0.042).

Conclusion
Nectin-4 could not be confirmed as a prognostic marker in pRCC in general. Due to its high abundance on pRCC specimens Nectin-4 is an interesting target for therapeutical approaches e.g. with EV. Clinical trials are warranted to elucidate its role in the pRCC treatment landscape.
Estimating Ground Snow Load Based on Ground Snow Depth and Climatological Elements for Snow Hazard Assessment in Northeastern China
Authors: Mo Huamei , Zhang Guolong , Zhang Qingwen , Hong H. P. , Fan Feng 
Published: September 2022

AbstractExtreme snow loads can collapse roofs. This load is calculated based on the ground snow load (that is, the snow water equivalent on the ground). However, snow water equivalent (SWE) measurements are unavailable for most sites, while the ground snow depth is frequently measured and recorded. A new simple practical algorithm was proposed in this study to evaluate the SWE by utilizing ground snow depth, precipitation data, wind speed, and air temperature. For the evaluation, the precipitation was classified as snowfall or rainfall according to the air temperature, the snowfall or rainfall was then corrected for measurement error that is mainly caused by wind-induced undercatch, and the effect of snow water loss was considered. The developed algorithm was applied and validated using data from 57 meteorological stations located in the northeastern region of China. The annual maximum SWE obtained based on the proposed algorithm was compared with that obtained from the actual SWE measurements. The return period values of the annual maximum ground snow load were estimated and compared to those obtained according to the procedure suggested by the Chinese structural design code. The comparison indicated that the use of the proposed algorithm leads to a good estimated SWE or ground snow load. Its use allowed the estimation of the ground snow load for sites without SWE measurement and facilitated snow hazard mapping.
A weighted inequality for trigonometric series
Authors: Coppola Giovanni , Laporta Maurizio 
Published: September 2022

AbstractBy applying Pitt’s inequality we prove a weighted $$L^p$$

L
p

version of Gallagher’s inequality for trigonometric series. Furthermore, we consider a family of weights generated by a smoothing process, via convolution operation, whose first steps are the indicator function of a compact interval and the so-called Cesàro weight supported in the same interval. The eventual aim is the comparison of such weights in view of possible refinements of our inequality for $$p=2$$

p
=
2

.
Bures–Wasserstein geometry for positive-definite Hermitian matrices and their trace-one subset
Authors: Oostrum Jesse van 
Published: September 2022

AbstractIn his classical argument, Rao derives the Riemannian distance corresponding to the Fisher metric using a mapping between the space of positive measures and Euclidean space. He obtains the Hellinger distance on the full space of measures and the Fisher distance on the subset of probability measures. In order to highlight the interplay between Fisher theory and quantum information theory, we extend this construction to the space of positive-definite Hermitian matrices using Riemannian submersions and quotient manifolds. The analog of the Hellinger distance turns out to be the Bures–Wasserstein (BW) distance, a distance measure appearing in optimal transport, quantum information, and optimisation theory. First we present an existing derivation of the Riemannian metric and geodesics associated with this distance. Subsequently, we present a novel derivation of the Riemannian distance and geodesics for this metric on the subset of trace-one matrices, analogous to the Fisher distance for probability measures.
Comparison of tissue culture-induced variation in triticale regenerants obtained by androgenesis and somatic embryogenesis
Authors: Pachota Katarzyna A. 
Published: September 2022

AbstractTriticale is becoming an increasingly important livestock crop production. This is evidenced by increasing triticale-producing areas and by improved yields. In addition, meeting the increasing demand for cereals involves the introduction of high-yielding and stress-resistant varieties into breeding. In vitro culture techniques can accelerate the development of new varieties. Therefore, it seems extremely important to develop efficient plant regeneration methods through in vitro cultures and to understand the mechanisms involved in gaining regenerants. Obtaining regenerants of triticale through somatic embryogenesis and androgenesis may lead to tissue culture-induced variation. In the present study, we compared regenerants obtained in both regeneration systems (anther and immature zygotic embryo cultures), considering the level of genetic and epigenetic changes observed in different DNA sequence contexts for methylated cytosine (CG, CHG, CHH). The changes concerning the DNA sequence (so-called sequence variation) and the changes concerning the DNA methylation patterns, i.e., the removal of methylated cytosine (DNA demethylation) and the introduction of methylation to cytosine (de novo DNA methylation), were analyzed. We observed that regenerants derived via somatic embryogenesis and androgenesis differ notably for demethylation in the symmetrical CG sequence context and de novo methylation in the asymmetrical CHH context. These changes may be related to the reprogramming of microspore development from gametophytic to sporophytic and lack of such process in zygotic embryos.
Phytochemical Investigation of Egyptian Spinach Leaves, a Potential Source for Antileukemic Metabolites: In Vitro and In Silico Study
Authors: Abdelgawad Shimaa M. , Hetta Mona H. , Ibrahim Mohamed A. , Balachandran Premalatha , Zhang Jin , Wang Mei , Fawzy Ghada A. , El-Askary Hesham I. , Ross Samir A. 
Published: September 2022

AbstractSpinacia oleracea L., Amaranthaceae, leaves cultivated in Egypt demonstrated a potential antileukemic activity against the chronic myeloid leukemia, K562 cell line. Thus, the aim of this study is to carry out a phytochemical investigation of S. oleracea leaves as well as the isolation of its antileukemic phytoconstituents. Phytochemical investigation of S. oleracea leaves resulted in the isolation of seventeen known compounds. The biological study revealed that compounds hexaprenol, phytol, and 18-[(1-oxohexadecyl) oxy]-9-octadecenoic acid exhibited a remarkable antiproliferative activity against K562 cells in vitro. A mechanistic in silico study showed that hexaprenol, phytol, and 18-[(1-oxohexadecyl) oxy]-9-octadecenoic acid exhibited a strong binding affinity towards topoisomerase (docking score −12.50, −9.19, and −13.29 kcal/mol, respectively), and showed as well a strong binding affinity towards Abl kinase (docking score −11.91, −9.35, and −12.59 kcal/mol, respectively). Molecular dynamics study revealed that 18-[(1-oxohexadecyl) oxy]-9-octadecenoic acid produced stable complexes with both topoisomerase and Abl kinase with RMSD values of 1.81 and 1.85 Å, respectively. As a result of our findings, we recommend more in vivo and preclinical studies to confirm the potential benefit of spinach leaves for chronic myeloid leukemia patients.
Graphical Abstract
Effect of annealing on the microstructure and properties of IN 625 specimens manufactured by selective laser melting
Authors: Sitek Ryszard , Ciftci Jakub , Moszczyńska Dorota , Maj Piotr , Ura-Bińczyk Ewa , Warzybok Piotr , Cieślik Iwona , Wiśniewski Paweł , Mizera Jarosław 
Published: September 2022

Abstract
The study examines the effect of the annealing on the microstructure, tensile strength (small flat dog-bone specimen size with 5 mm dimension of measuring base) and corrosion resistance of IN 625 nickel superalloy specimens manufactured by means of selective laser melting method (SLM). The annealing of such specimens was carried out in a chamber furnace in a protective atmosphere of argon at a temperature of 1038 °C for 1 h. The cooling process was carried out in an atmosphere of air at ambient temperature. The microstructure of the IN 625 nickel superalloy after the 3D printing process and after the post-process heat treatment (HT) was examined by means of scanning electron microscopy (SEM) and electron backscatter diffraction (EBSD). The results showed a uniform microstructure after the SLM process with element microsegregation. The cooling rate in the heat treatment was not sufficient which caused precipitation at the grain boundaries, most probably carbides and resulted in only a partial increase in ductility much lower than that of the material in initial state despite the high temperature applied during the annealing. The strength in the HT was on a level comparable to as-build state, 852 MPa and 891 MPa, respectively. Additional corrosion resistance tests were performed by the potentiodynamic method in a 3.5% NaCl solution at room temperature. HT increased the current density variation from i
pass due to the formed precipitates. Our studies show that the size effect is an important factor when assessing the properties of IN 625 obtained using SLM. Despite similar microstructure, the structure defects play a more significant role which translates into lower mechanical properties than in normal sized specimens defined by the standard ASTM E8.
From Pioneer Historiography to Patriotic History: Constructing Usable Pasts in Zimbabwe (1890–2018)
Authors: Pinto Teresa Nogueira 
Published: September 2022

AbstractDifferent political projects and ideological positions are founded upon distinct accounts of the past, each with their own emphases, silences, and omissions. The case of Zimbabwe illustrates this connection between power and history. Whereas the myths of colonial historiography provided legitimization frameworks for settler colonialism, “patriotic history” became a key element of the legitimation strategy implemented by the post-independence regime. Pinto analyses how history and historiography were incorporated into narratives of power legitimization in both pre- and post-independence Zimbabwe and how, in the late 90s, history and historiography became critical sites of political polarization and contestation.
Internal Politics and Activism in Former Rebel Parties
Authors: Ibáñez Marcela , Jäger Kai 
Published: September 2022

AbstractWho are the supporters of former rebel parties? Drawing on the classical party literature, we argue that the support base of former rebel parties consists predominantly of activists. These supporters are dissatisfied with intra-party politics because the benefits and costs of a rebel-to-party transformation are unequally distributed between them and the leadership. We test our arguments by examining the case of the novel FARC party (Comunes) in Colombia. Based on a unique sample of FARC supporters, we obtained unprecedented insight into the internal affairs of the FARC. Our survey design allowed us to generate an over-time comparison between FARC and other party supporters in the Colombian political system. The empirical analysis shows that in comparison, FARC supporters tend to be more politically active as well as more dissatisfied with internal politics. Furthermore, dissatisfaction with democracy and the peace agreement increased after their first electoral cycle.
Waco's First Black School Board Trustees: Navigating Institutional White Supremacy in 1970s Texas
Authors: James-Gallaway ArCasia D. 
Published: September 2022

AbstractThrough the lens of the school board, this essay examines school governance dynamics as a southern, historically white public school district struggled to implement school desegregation. In 1976, the city of Waco simultaneously elected its school district's first trustees of Color, Dr. Emma Louise Harrison and Rev. Robert Lewis Gilbert. Harrison and Gilbert used distinctly different political strategies to navigate the racially hostile school board environment, but ultimately, as this article demonstrates, neither strategy enabled them to overcome white supremacy in Waco. This seemingly obvious point reveals a notable yet underemphasized drawback of school desegregation: that it failed to upend structural racial injustice. The case of Harrison and Gilbert illustrates that this limitation was reflected in the token number of Black trustees on the boards of desegregated schools and the concerted white resistance they met in working to spur meaningful racial change.
Evaluation of a Web-based learning system for skills in removing personal protective equipment for highly infectious diseases—A randomized controlled trial
Authors: Sato Shota , Iijima Sachiko 
Published: September 2022

AbstractObjective:Which educational method is best for 3-month retention of proper skills in removing personal protective equipment (PPE) in the setting of highly infectious diseases is unclear. We evaluated the effectiveness of a Web-based learning system after 3 months of use.Setting:One general hospital in Japan.Intervention:We conducted a randomized, nonblinded, parallel-group trial with 35 nurses using the substitution block method. At baseline, both groups received face-to-face training in putting on and removing PPE. The intervention group was given access to the Web-based learning system we developed using Modular Object-Oriented Dynamic Learning Environment (Moodle). After 3 months, we assessed both groups regarding knowledge and skills in removing PPE using a 34-point test, fluorescent markers, and video recordings.Results:Overall, 34 participants completed the trial: 16 in the intervention group and 18 in the control group. Postintervention knowledge test scores (1.3 vs −0.8; P = .013; effect size r = .42) and deviations from the required procedure (−5.4 vs 1.9; P = .001; effect size r = .55) were significantly better in the intervention group than in the control group. The number of contaminated sites (−0.5 vs 0.4; P = .128; effect size r = .26) and contaminated participants (−18.7% vs 11.1% decreased in the intervention group, and increased in the control group, although this was not significant (P = .242; effect size ϕ = .47).Conclusions:This learning system was an effective educational method in maintaining and improving knowledge of proper PPE removal skills. The number of deviations from the required procedure decreased, and this reduction continued after 3 months.Clinical trials identifier:Evaluation of the Web materials for learning PPE removal skills in the setting of highly infectious diseases. University Hospital Medical Information Network, UMIN000042725: https://center6.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000048767
The energy density of meals and snacks consumed by young Australian adults (18–30 years old) are influenced by preparation location but not screen use nor social interactions: findings from the MYMeals wearable camera study
Authors: Chan Virginia , Davies Alyse , Wellard-Cole Lyndal , Allman-Farinelli Margaret 
Published: September 2022

Abstract
The present study examined the association of contextual factors (social and food preparation location) with the energy density of meals and snacks consumed in a sample of young Australian adults (18–30 years old) identified using wearable camera technology. Over three consecutive days, a subsample of young adults wore a wearable camera that captured images in 30 s intervals. Eating episodes from 133 participants were annotated for preparation location and social context (covering social interaction and screen use). Over the same period, participants completed daily 24 h recalls. The nutritional composition of meals and snacks was calculated by matching the items identified in the camera to the 24 h recall using time and date stamps. Self-reported data (weight and height) was used to calculate body mass index and (residential postcode) to assign socio-economic status. The association of context and demographic factors with energy density was determined using a mixed linear regression model employing the bootstrap method with bias-corrected and accelerated. In total, 1817 eating episodes were included in the analysis (n 8 preparation unclear and n 15 food components could not be identified excluded). Food prepared within the home was 1⋅1 kJ/g less energy-dense than other preparation locations. Lunches (CI −1⋅7 to −0⋅3) and dinners (CI −1⋅6 to −0⋅5) were both 1⋅0 kJ/g lower in energy density than breakfasts. Snacks were 3⋅5 kJ/g (CI 2⋅8–4⋅1) more energy-dense than breakfasts. Food prepared outside the home and food consumption during snacking appear to be adversely contributing to energy-dense food intake.
CANONICAL DECOMPOSITION AND QUIVER REPRESENTATIONS OF TYPE OVER FINITE FIELDS
Authors: CHEN QINGHUA , LIU YE 
Published: September 2022

AbstractLet Q be a quiver of type
$\tilde {A}_n$
. Let
$\alpha =\alpha _1+\alpha _2+\cdots +\alpha _s$
be the canonical decomposition. For the polynomials
$M_Q(\alpha ,q)$
that count the number of isoclasses of representations of Q over
${\mathbb F}_q$
with dimension vector
$\alpha $
, we obtain a precise relation between the degree of
$M_Q(\alpha ,q)$
and that of
$\prod _{i=1}^{s} M_Q(\alpha _i,q)$
for an arbitrary dimension vector
$\alpha $
.
THE CORNERSTONE OF OUR LAW: EQUALITY, CONSISTENCY AND JUDICIAL REVIEW
Authors: Foran Michael 
Published: September 2022

AbstractEquality before the law is a foundational principle of the common law and is of particular importance for administrative law, given the connection between judicial review and the rule of law. Analysis as to the precise requirements of this principle can help us better to understand the role that obligations to act consistently play within judicial review. This article will examine whether consistency ought to be classed as a separate ground of review and argue that this is unnecessary. Examination of the role that legal equality plays within common law reason generally will shed light on the role that it plays within administrative law in particular. Consistency is best conceived as a background principle, informed by the value of legal equality, housed within reasonableness review and not as a separate ground of review that could elide the distinction between review and appeal.
Concentrations of organotin compounds in aquatic biota in coastal waters of Johor, Malaysia
Authors: Ohji Madoka , Shibayama Kota , Harino Hiroya , Hayashizaki Ken-Ichi , Yusoff Fatimah Md. , Inoue Koji 
Published: September 2022

AbstractThe concentrations of organotin (OT) compounds, butyltin (BT) and phenyltin (PT), in aquatic organisms from Merambong and Tinggi Island, Malaysia, which differ in industrial and economic activities, were measured. Tributyltin (TBT) compounds among BTs ranged from 2.9–28 and <0.1–21 ng g−1 ww in aquatic organisms from Merambong and Tinggi Island, respectively. Triphenyltin (TPT) compounds among PTs ranged from <0.1–25 ng g−1 ww and <0.1–61 ng g−1 ww in aquatic organisms from Merambong and Tinggi Island, respectively. A survey of OT concentrations among the species of OT compounds revealed that the concentrations of BTs and PTs in crabs and clams were high while those in fish were low. Correlation analysis with stable nitrogen isotopes suggest that OT compounds did not accumulate in aquatic organisms through the food web. The measurement of OT compounds in tissues and organs of fish revealed that BT concentrations in liver were higher than those in muscle and that BTs were detected in eggs of fish.
Destructive plasticity and the microbial geopolitics of childhood malnutrition
Authors: du Plessis Gitte 
Published: September 2022

AbstractEngaging Catherine Malabou's philosophical work on biological plasticity, this article combines microbiological and geopolitical analysis of the deadliest manifestations of childhood malnutrition. At the scale of microbiology, childhood malnutrition is a devastating condition and a mystery to which it seems microbiomes – the ecosystems of microbes in the gut – hold a key. At the scale of geopolitics, childhood malnutrition is a calamity generated by racial capitalism, poverty, and underdevelopment. What should we do with the plasticity that makes us? Malabou asks. Engaging philosophically with the plastic materiality of microbiomes in childhood malnutrition, the article focuses on destructive plasticity as an ontological alternative to what science on malnutrition pursues as a problem of causality. This leads to an argument that medicine, as well as humanitarian, security, and development interventions, must reckon with the destructive plasticity of what is in essence a political disease of annihilation. The article ends by speculating on resistance via the biological act of nurturing.