bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Development and Validation of a Subscale for the School-Age Child Behavior CheckList to Screen for Autism Spectrum Disorder
Authors: Offermans Julia E. , de Bruin Esther I. , Lange Aurelie M. C. , Middeldorp Christel M. , Wesseldijk Laura W. , Boomsma Dorret I. , Dieleman Gwen C. , Bögels Susan M. , van Steensel Francisca J. A. 
Published: February 2022

AbstractThe first aim of this study was to construct/validate a subscale—with cut-offs considering gender/age differences—for the school-age Child Behavior CheckList (CBCL) to screen for Autism Spectrum Disorder (ASD) applying both data-driven (N = 1666) and clinician-expert (N = 15) approaches. Further, we compared these to previously established CBCL ASD profiles/subscales and DSM-oriented subscales. The second aim was to cross-validate results in two truly independent samples (N = 2445 and 886). Despite relatively low discriminative power of all subscales in the cross-validation samples, results indicated that the data-driven subscale had the best potential to screen for ASD and a similar screening potential as the DSM-oriented subscales. Given beneficial implications for pediatric/clinical practice, we encourage colleagues to continue the validation of this CBCL ASD subscale.
Verändern sich reflexionsbezogene Einstellungen von Studierenden nach der Nutzung von Schülerrückmeldungen im Praxissemester? Befunde einer Interventionsstudie
Authors: Göbel Kerstin , Neuber Katharina 
Published: February 2022

ZusammenfassungDie Reflexion eigenen Unterrichts ist ein zentraler Bestandteil der schulpraktischen Lehrerinnnen- und Lehrerausbildung. Die Rückmeldungen von Schülerinnen und Schülern zum Unterricht können für diese Reflexion genutzt werden, da sie die Wahrnehmung der angehenden Lehrpersonen auf den Unterricht sinnvoll ergänzen können. Bislang werden Schülerrückmeldungen zum Unterricht jedoch nur selten in der Lehrpersonenausbildung eingesetzt. Die vorliegende Prä-Post-Kontrollgruppen-Studie prüft mittels Kovarianzanalysen, inwieweit die strukturierte Reflexion von Schülerrückmeldungen den Aufbau günstiger Einstellungen gegenüber Reflexion von Lehramtsstudierenden fördert und welche individuellen Voraussetzungen (Geschlecht, Selbstwirksamkeitserwartung, antizipierte Beanspruchung im Lehrerberuf) hierfür relevant sind. Die Interventionsgruppe (IG,n = 53) erhielt ein strukturiertes Reflexionsangebot unter Nutzung von Schülerrückmeldungen zum eigenen Unterricht im Praxissemester; die Kontrollgruppe (KG,n = 73) erhielt eine Praxissemesterbegleitung ohne ein entsprechendes Reflexionsangebot. Die Analyseergebnisse machen deutlich, dass die Studierenden im Praxissemester der Reflexion im Lehrerberuf eine hohe Bedeutung beimessen und insgesamt eine positive Haltung gegenüber Schülerrückmeldungen einnehmen. Im Hinblick auf die Einstellungsveränderungen zeigen sich nur bedingt Gruppenunterschiede oder Effekte individueller Voraussetzungen. Die Entwicklungen in der IG weisen auf den Bedarf einer konzeptionellen Weiterentwicklung des eingesetzten Reflexionsangebots hin.
Transformation archetypes in global food systems
Authors: Dornelles André Zuanazzi , Boonstra Wiebren J. , Delabre Izabela , Denney J. Michael , Nunes Richard J. , Jentsch Anke , Nicholas Kimberly A. , Schröter Matthias , Seppelt Ralf , Settele Josef , Shackelford Nancy , Standish Rachel J. , Oliver Tom H. 
Published: February 2022

AbstractFood systems are primary drivers of human and environmental health, but the understanding of their diverse and dynamic co-transformation remains limited. We use a data-driven approach to disentangle different development pathways of national food systems (i.e. ‘transformation archetypes’) based on historical, intertwined trends of food system structure (agricultural inputs and outputs and food trade), and social and environmental outcomes (malnutrition, biosphere integrity, and greenhouse gases emissions) for 161 countries, from 1995 to 2015. We found that whilst agricultural total factor productivity has consistently increased globally, a closer analysis suggests a typology of three transformation archetypes across countries: rapidly expansionist, expansionist, and consolidative. Expansionist and rapidly expansionist archetypes increased in agricultural area, synthetic fertilizer use, and gross agricultural output, which was accompanied by malnutrition, environmental pressures, and lasting socioeconomic disadvantages. The lowest rates of change in key structure metrics were found in the consolidative archetype. Across all transformation archetypes, agricultural greenhouse gases emissions, synthetic fertilizer use, and ecological footprint of consumption increased faster than the expansion of agricultural area, and obesity levels increased more rapidly than undernourishment decreased. The persistence of these unsustainable trajectories occurred independently of improvements in productivity. Our results underscore the importance of quantifying the multiple human and environmental dimensions of food systems transformations and can serve as a starting point to identify potential leverage points for sustainability transformations. More attention is thus warranted to alternative development pathways able of delivering equitable benefits to both productivity and to human and environmental health.
Proteomic and Metabolomic Profiling in Soft Tissue Sarcomas
Authors: Chadha Madhumeeta , Huang Paul H 
Published: February 2022

Opinion statementAdvances in proteomic and metabolomic technologies have accelerated our understanding of multiple aspects of cancer biology across distinct tumour types. Here we review the current state-of-the-art in the use of proteomics and metabolomics in soft tissue sarcomas. We highlight the utility of these Omics-based methodologies to identify new drug targets, synthetic lethal interactions, candidate therapeutics and novel biomarkers to facilitate patient stratification. Due to the unbiased and global nature of these profiling methods to assess the levels of protein expression, post-translational modifications such as phosphorylation and glycosylation as well as key metabolites, many of these findings have broad applications not just in specific histotypes but across multiple STS subtypes. Specific examples of proteomic and metabolomic findings that have led to the development of early phase clinical trials of investigational agents will be discussed. While promising, the use of these technologies in the study of sarcoma is still limited, and there is a need for further research in this area. In particular, it would be important to integrate these approaches with other Omics strategies such as genomics and epigenomics as well as implement these tools alongside clinical trials in order to maximize the impact of these tools on our biological understanding and treatment of this group of rare diseases of unmet need.
A simplified protocol for the detection of blood, saliva, and semen from a single biological trace using immunochromatographic tests
Authors: Basset Patrick , Blandin Prisca , Grini Annalisa , Delemont Séverine , Samie Lydie , Castella Vincent 
Published: February 2022

AbstractThe detection of body fluids (e.g., blood, saliva or semen) provides information that is important both for the investigation and for the choice of the analytical protocols. Because of their sensitivity, specificity, as well as their simplicity of use, immunochromatographic tests are widely applied. These tests target different body fluids and generally require specific buffer solutions. If one needs to investigate whether the material is of a specific nature (e.g., blood), this is fine. However, if the material can also contain other material (e.g., saliva or semen) then the use of different tests can be problematic. Indeed, if the different tests require different buffers, it will not be possible to perform all tests on the exact same specimen.In this study, we assess the use of the RSID™-universal buffer to perform three immunochromatographic tests (HEXAGON OBTI, RSID-saliva, and PSA Semiquant) as well as spermatozoa detection. We use the same eluate for the detection of all three body fluids. The proposed protocol provides similar results to those obtained when each test is conducted independently. Furthermore, it does not affect the quality of the DNA profiles. The main advantage of this protocol is that the results of the presumptive test(s) and of the DNA analyses are representative of the exact same specimen.
Physical Examination of the Hip: Assessment of Femoroacetabular Impingement, Labral Pathology, and Microinstability
Authors: Wong Stephanie E. , Cogan Charles J. , Zhang Alan L. 
Published: February 2022

Abstract
Purpose of Review
Determining the correct diagnosis can be challenging in patients presenting with hip pain. The physical examination is an essential tool that can aid in diagnosis of hip pathology. The purpose of this review is to provide an updated summary of recent literature on the physical exam of the hip, particularly as it relates to diagnosis of femoroacetabular impingement (FAI) syndrome, labral injury, and hip microinstability.

Recent Findings
Physical exam findings consistent with the diagnosis of FAI include reduced supine hip internal rotation and positive flexion-adduction-internal rotation maneuvers. Labral tears can be detected on exam with the Scour test. Studies demonstrate altered hip biomechanics in patients with FAI during activities such as walking and squatting. Those with FAI have slower squat velocities, slower sit-to-stand tests, and increased hip flexion moments during ambulation. Hip microinstability is a dynamic process, which can occur after prior hip arthroscopy. For hip microinstability, the combination of the three following positive tests (anterior apprehension, abduction-extension-external rotation, and prone external rotation) is associated with a 95% likelihood of microinstability as confirmed by examination under anesthesia at the time of surgery.

Summary
A comprehensive hip physical exam involves evaluation of the hip in multiple positions and assessing hip range of motion, strength, as well as performing provocative testing. A combination of physical exam maneuvers is necessary to accurately diagnose FAI syndrome and labral pathology as individual tests vary in their sensitivity and specificity. While an elevated level of suspicion is needed to diagnose hip microinstability, the provocative tests for microinstability are highly specific.
Recent Developments in the Assessment of Nutrition Knowledge in Athletes
Authors: Tam Ryan , Gifford Janelle A. , Beck Kathryn L. 
Published: February 2022

AbstractPurpose of ReviewAdequate nutrition knowledge may influence dietary behaviour, and the performance and health of athletes. Assessment of the nutrition knowledge of athletes can inform practice and provide a quantitative way to evaluate education interventions. This article aims to review nutrition knowledge questionnaires published in the last 5 years to identify advances, possible improvements in questionnaire development and design, and challenges that remain.Recent FindingsTwelve new or modified questionnaires were identified. All had undergone validity and reliability testing. Advancements included quantitative measures of content validity and Rasch analysis. Online questionnaires were common, with at least seven using this format. Advances included use of images (n = 2), automated scored feedback (n = 1), and use of applied questions.SummaryWhile advancements have been made in validation and reliability testing and electronic delivery, new questionnaires would benefit from interactive and attractive features including images, provision of electronic feedback, and applied questions.
Handling multicollinearity in quantile regression through the use of principal component regression
Authors: Davino C. , Romano R. , Vistocco D. 
Published: February 2022

AbstractIn many fields of applications, linear regression is the most widely used statistical method to analyze the effect of a set of explanatory variables on a response variable of interest. Classical least squares regression focuses on the conditional mean of the response, while quantile regression extends the view to conditional quantiles. Quantile regression is very convenient, whereas classical parametric assumptions do not hold and/or when relevant information lies in the tails and therefore the interest is in modeling the conditional distribution of the response at locations different from the mean. A situation common to most regression applications is the presence of strong correlations between predictors. This leads to the well-known problem of collinearity. While the effects of collinearity on least squares estimates are well investigated, this is not the case for quantile regression estimates. This paper aims to explore the collinearity problem in quantile regression. First, a simulation study analyses the problem concerning different degrees of collinearity and various response distributions. Then the paper proposes using regression on latent components as a possible solution to collinearity in quantile regression. Finally, a case study shows the assessment of the quality of service in the presence of highly correlated predictors.
Paraconiothyrium fuckelii, Diaporthe eres and Neocosmospora parceramosa causing cane blight of red raspberry in Northern Italy
Authors: Guarnaccia Vladimiro , Martino Ilaria , Brondino Luca , Gullino Maria Lodovica 
Published: February 2022

AbstractRed raspberry (Rubus idaeus L.) represents a relevant crop which production has largely increased worldwide during the last decade. Cane blight is one of the most common diseases of red raspberry and it can produce considerable losses. During 2019–2021, surveys were conducted in red raspberry orchards in Cuneo province, Northern Italy, to investigate the etiology and pathogen diversity in association with cane blight. Eleven isolates were collected from symptomatic plants of the cultivars ‘Diamond Jubilee’ and ‘Grandeur’, and were identified through multi-locus phylogenies and morphological features. Three fungal species were identified: Paraconiothyrium fuckelii, Diaporthe eres and Neocosmospora parceramosa. Four different genomic regions were included in the molecular analyses: ITS, tef1, tub2 and rpb2. The species pathogenicity was confirmed and P. fuckelii was revealed as the most aggressive. This study provides an insight into raspberry cane blight in Italy and the genomic loci sequencing lay the basis to develop specific diagnostic protocols to monitor the presence of pathogens and to prevent disease spread, adopting effective integrated control strategies.
New approaches: Use of assisted natural succession in revegetation of inhabited arid drylands as alternative to large-scale afforestation
Authors: Huebner Lorenz , Fadhil Al-Quraishi Ayad M. , Branch Oliver , Gaznayee Heman A. A. 
Published: February 2022

AbstractIt is a great concept to let nature do the work of revegetation, however in semi-arid and arid regions the process of natural succession, if it occurs at all, typically requires many years of undisturbed development until an increase in biomass becomes measurable, hence it rather is applied to remote, sparsely populated regions and may be underrated as a measure to restore native vegetation, particularly in inhabited arid areas. What are the factors that make arid successional processes successful, how to expedite, and how to enable their use for the ecological revegetation of densely populated drylands? We review restoration methods that combine the planting of shelterbelt compartments with successional revegetation of the internal area, protected from wind and drought. Various measures of assisted natural succession can be applied to greatly accelerate the revegetation, including soil tillage, amendment with organic matter and the inoculation with cyanobacteria or lichens to form biocrusts. The aim is to initiate the development of native, water-saving savanna with biodiversity, resilience and adaptability to climate change. A narrow twin shelterbelt module could facilitate the use of natural succession within inhabited and peri-urban areas, also serving as protective greenbelt for cities. A pilot is planned in a peri-urban area of Northern Iraq, with a successional area of 125–150 m between shelterbelts. Land-use of agriculture, gardening and recreation can be integrated within the successional area, which also generates engagement of residents in the maintenance work. Planting of shelterbelts is required on 10–25% (not 100%) of the restoration area, therefore the use of assisted succession within protective compartments is expected to have both, ecological and economic advantages over large-scale afforestation.
Mixed Methods Process Evaluation of a Sanitation Behavior Change Intervention in Rural Odisha, India
Authors: Sclar Gloria D. , Routray Parimita , Majorin Fiona , Udaipuria Shivika , Portela Gerard , Koehne William J. , Nagel Corey L. , Sola Steven , Caruso Bethany A. 
Published: February 2022

Abstract

Background
Process evaluations of public health programs are critical to understand if programs were delivered as intended and to identify improvements for future implementations. Here we present a mixed methods process evaluation of the Sundara Grama intervention, which sought to improve latrine use and safe child feces disposal among latrine-owning households in rural Odisha, India.

Methods
The Sundara Grama intervention was delivered to 36 villages in Puri district by a grassroots non-governmental organization (NGO) and included eight activities: palla performance, transect walk, community meeting, community wall painting, mother’s meeting, positive deviant household recognition, household visit, and latrine repairs. The process evaluation quantitatively assessed fidelity, dose delivered, and reach, and qualitatively examined recruitment, context, and satisfaction. Quantitative data collection included an activity observation survey, activity record, and endline trial survey. Qualitative data collection included an activity observation debrief and in-depth interviews with NGO mobilizers. For the quantitative data, a ‘delivery score’ was calculated for each activity, as well as the proportion of target participants in attendance. Qualitative data were analyzed using thematic analysis.

Results
Mean delivery scores, reported as a percentage, were moderate to high. Household visit activities (97% general visit, 96% positive deviant visit) and the mother’s meeting (81%) had the highest delivery scores, followed by the palla (77%), transect walk (77%), and community meeting (60%). Activities were attended, on average, by 30% to 73% of latrine-owning households. Several factors aided delivery, including pre-intervention rapport building visits and village stakeholder support. Factors that hindered delivery included inclement weather, certain recruitment strategies, and village social dynamics.

Conclusions
Overall, the Sundara Grama intervention was implemented as intended and achieved good reach. The findings suggest education-entertainment strategies, like the palla, and multi-level communication approaches are particularly beneficial. The results also showcase the importance of examining the implementer experience and broader context.
Auf dem Weg zu einer Kulturpsychologie
Authors: Wolfradt Uwe , Allolio-Näcke Lars 
Published: February 2022

ZusammenfassungIm vorliegenden Beitrag wird der akademische Lebensweg zweier Kulturpsychologen nachgezeichnet: Julius Bahle (1903–1986) und Hans Werbik (1941–2021). Trotz ihrer unterschiedlichen historischen Erfahrungen weisen die Biografien der beiden Wissenschaftler viele Parallelen auf. Ausgehend von der Liebe zur Musik erkannten sie früh, dass das subjektive Erleben einer Melodie nicht durch die „objektiven“ Methoden einer naturwissenschaftlichen Psychologie bestimmt werden kann. Beide Persönlichkeiten hatten aufgrund ihrer frühen politischen Prägung ein hohes ethisches Bewusstsein, welches den Menschen als schöpferisch frei handelndes Wesen verstand. Während Bahle aufgrund der zeithistorischen Umstände in der Nachkriegszeit eine akademische Laufbahn verwehrt blieb, konnte Werbik als Hochschullehrer einen Kreis von Gleichgesinnten finden und die Gesellschaft für Kulturpsychologie gründen. Psychologie als Kulturwissenschaft, die dem subjektiven Erleben gerecht werden soll, verband beide Persönlichkeiten.
Which pharmacists are performing antimicrobial stewardship: A national survey and a call for collaborative efforts
Authors: Dionne Brandon , Wagner Jamie L. , Chastain Daniel B. , Rosenthal Meagen , Mahoney Monica V. , Bland Christopher M. 
Published: February 2022

Abstract

Objectives:
To determine how pharmacists with formal antimicrobial stewardship program (ASP) responsibilities prioritize their time and pharmacists without formal antimicrobial stewardship program responsibilities contribute to ASP activities.

Design:
A nationwide survey.

Respondents:
Members of the American College of Clinical Pharmacy who subscribe to the following practice and research network e-mail listservs: infectious diseases, adult medicine, cardiology, critical care, hematology–oncology, immunology and transplantation, and pediatrics.

Methods:
A survey was distributed via listservs. Respondents were asked about their personal and institutional demographics and ASP activities.

Results:
In total, 245 pharmacists responded: 135 pharmacists with formal antimicrobial stewardship program responsibilities; 110 pharmacists without formal antimicrobial stewardship program responsibilities. Although most respondents had completed a general pharmacy residency (85%), only 20% had completed an infectious diseases (ID) specialty residency. Among pharmacists with formal antimicrobial stewardship program responsibilities, one-third had no formal training or certification in ID or ASP. Pharmacists without formal antimicrobial stewardship program responsibilities spent ∼12.5% of their time per week on ASP activities, whereas pharmacists with formal antimicrobial stewardship program responsibilities spent 28% of their time performing non-ASP activities. Pharmacists with formal antimicrobial stewardship program responsibilities were more likely than pharmacists without formal antimicrobial stewardship program responsibilities to perform antibiotic guideline development (P < .001), antibiotic-related education (P = .002), and direct notification of rapid diagnostic results (P = .018). Pharmacists with formal antimicrobial stewardship program responsibilities without formal ID training or certification spent less time on ASP activities and were more likely to perform lower-level interventions.

Conclusions:
Many ASP activities are being performed by pharmacists without formal ID training. To ensure the future success of ASPs, pharmacists with formal antimicrobial stewardship program responsibilities should have adequate training to meet more advanced metrics, and more pharmacists without formal antimicrobial stewardship program responsibilities should be included in basic interventions.