bluuebunny/crossref_metadata_2025_split huggingface dataset:
The elite judo female athlete’s heart
Authors: Milovančev Aleksandra , Petrović Milovan , Miljković Tatjana , Ilić Aleksandra , Mudrinić Tatjana Redžek , Miljković Aleksandar , Ivanov Olivera , Tripunović Jelena , Anđelic Bogdan , Bianco Antonino , Drid Patrik 
Published: August 2022

Purpose: There is a paucity of data on physiological heart adaptation in elite-level judo female athletes. This study aimed to assess left ventricular morphology and function in highly trained elite female judokas.Methods: The study prospectively included 18 females aged 23.5 ± 2.25 years, nine elite level judokas, and nine healthy non-athlete volunteers. All participants underwent a medical examination, electrocardiogram, and transthoracic 2D echocardiogram. Left ventricular diastolic and systolic diameters and volumes were determined, and parameters of left heart geometry and function (systolic and diastolic) were measured, calculated, and compared between groups.Results: When groups were compared, judokas had significantly increased left ventricular cavity dimensions p &lt; 0.01, left ventricular wall thickness p &lt; 0.01, and volumes p &lt; 0.01. Elite female judokas exhibited left ventricular dilatation demonstrated as high prevalence increased end-diastolic volume/index, and increased end-systolic volume/index in 88.9% of judokas vs. 0% in controls, p &lt; 0.01. Left ventricle mass/index was significantly increased in judokas, p &lt; 0.01), with a 43.3% difference between groups. The majority (77.7%) of judokas had normal left ventricular geometry, although eccentric hypertrophy was revealed in 2 (22.2%) of judokas.Conclusion: Elite, highly trained female judokas exhibit significant changes in left heart morphology as a result of vigorous training compared to non-athletes. These findings suggest that female judokas athletes’ heart follows a pattern toward chamber dilatation rather than left ventricular wall hypertrophy.
Socioeconomic inequality in rehabilitation service utilization for schizophrenia in China: Findings from a 7-year nationwide longitudinal study
Authors: Ding Ruoxi , He Ping , Zheng Xiaoying 
Published: August 2022

AimsFew studies have focused on the utilization of rehabilitation services among people with schizophrenia. In this study, we aimed to examine the trend of pharmacological and psychotherapy service utilization among adults with schizophrenia and to identify the associated socioeconomic factors.MethodsData were obtained from the Second National Sample Survey on Disability in 2006 and from the follow-up investigation in 2007–2013. Individuals with schizophrenia were ascertained by the combination of self-reports and on-site diagnosis by psychiatrists. Random effect logistic regression models were applied to examine the socioeconomic disparity in service utilization and the time trend in the association.ResultsOverall, the percentage of individuals using pharmacological treatment services increased from 23.7 in 2007 to 55.0% in 2013, and the percentage of individuals using psychotherapy services increased from 11.4 to 39.4%. Living in rural areas, being illiterate, living in families with lower income and being uninsured were less likely to receive pharmacological treatment and psychotherapy. The pace of growth in service utilization was higher among individuals with rural residence, illiteracy or low-income status than among their counterparts with advantaged backgrounds.ConclusionsThis study demonstrated an upward trend in pharmacological treatment and psychotherapy service utilization and a downward trend in socioeconomic disparity among Chinese adults with schizophrenia. Future studies to explore the reasons for the observed changes and to identify policies for improving the health service access of this vulnerable group are warranted.
Revisiting the Raractocetus Fossils from Mesozoic and Cenozoic Amber Deposits (Coleoptera: Lymexylidae)
Authors: Li Yan-Da , Peris David , Yamamoto Shûhei , Hsiao Yun , Newton Alfred F. , Cai Chen-Yang 
Published: August 2022

The fossils once assigned to Raractocetus Kurosawa from the Mesozoic and Cenozoic amber deposits differ from extant Raractocetus in the longer elytra, the more strongly projecting metacoxae, and the hind wing with vein 2A forked. Thus, these fossils should be removed from Raractocetus. Cretoquadratus engeli Chen from Kachin amber appears to be conspecific with R. fossilis Yamamoto. As a result, R. fossilis and R. extinctus Yamamoto from Kachin amber, R. balticus Yamamoto from Baltic amber, and R. sverlilo Nazarenko, Perkovsky & Yamamoto from Rovno amber are transferred to Cretoquadratus Chen, as C. fossilis (Yamamoto) comb. nov., C. extinctus (Yamamoto) comb. nov., C. balticus (Yamamoto) comb. nov., and C. sverlilo (Nazarenko, Perkovsky & Yamamoto) comb. nov., and C. engeli syn. nov. is suggested to be a junior synonym of C. fossilis.
Dual antithrombotic therapy and gastroprotection in atrial fibrillation: an observational primary care study
Authors: Xie Charis Xuan , Robson John , Williams Crystal , Carvalho Chris , Rison Stuart , Raisi-Estabragh Zahra 
Published: August 2022

BackgroundPatients with both atrial fibrillation (AF) and cardiovascular disease (CVD) may receive dual antithrombotic therapy (DAT) with both an anticoagulant and ≥1 antiplatelet agents. Avoiding prolonged duration of DAT and use of gastroprotective therapies reduces bleeding risk.AimTo describe the extent and duration of DAT and use of gastroprotection in a primary care cohort of patients with AF.Design & settingObservational study in 1.2 million people registered with GPs across four east London clinical commissioning groups (CCGs), covering prescribing from January 2020–June 2021.MethodIn patients with AF, factors associated with DAT prescription, prolonged DAT prescription (>12 months), and gastroprotective prescription were characterised using logistic regression.ResultsThere were 8881 patients with AF, of whom 4.7% (n= 416) were on DAT. Of these, 65.9% (n= 274) were prescribed DAT for >12 months and 84.4% (n= 351) were prescribed concomitant gastroprotection. Independent of all other factors, females with AF were less likely to receive DAT than males (odds ratio [OR] 0.61, 95% confidence interval [CI] = 0.49 to 0.77). Similarly, older (aged ≥75 years) individuals (OR 0.79, 95% CI = 0.63 to 0.98) were less likely to receive DAT than younger patients. Among those with AF on DAT, pre-existing CVD (OR 3.33, 95% CI = 1.71 to 6.47) and South Asian ethnicity (OR 2.70, 95% CI = 1.15 to 6.32) were associated with increased gastroprotection prescriptions. Gastroprotection prescription (OR 1.80, 95% CI = 1.01 to 3.22) was associated with prolonged DAT prescription.ConclusionAlmost two-thirds of patients with AF on DAT were prescribed prolonged durations of therapy. Prescription of gastroprotection therapies was suboptimal in one in six patients. Treatment decisions varied by sex, age, ethnic group, and comorbidity. Duration of DAT and gastroprotection in patients with AF requires improvement.
Factors Influencing Age at Menarche, a School-Based Cross-Sectional Study
Authors: Novalia Novalia Kridayanti , Hery Sumasto  , Saadah Nurlailis , Surtinah Nani 
Published: August 2022

The last few years have seen the increasingly young age of menarche in teenagers. The average age of the national menarche from year to year is declining. The more children experience early menarche, the greater the risk of negative implications such as lack of personal hygiene, breast cancer, and early pregnancy. Menarche's age is influenced by nutritional, economic, pornographic, and genetic status. The purpose of this study was to determine the factors that affect menarche in adolescents aged 10-12 years. The research conducted is descriptive-analytic with a cross-sectional design. The population of MIN 3 Magetan students aged 10-12 years who have menstruated and have met the inclusion and exclusion criteria. The study sample was 87 respondents with a purposive sampling technique. Data collection using questionnaires. Statistical calculations are carried out by statistical and descriptive analysis with binary logistic regression tests. The average age of menarche is 11 years with the youngest age being 9 years and the oldest at 12 years, most female students experience early menarche (65.5%). There is an effect of nutritional status on menarche (p =0.048, Exp (B)= 4.3), there is an economic influence on menarche (p=0.000, Exp (B)= 11.3), there is an influence of pornographic exposure on menarche (p=0.001, Exp (B)= 12.1), and there is no genetic or age influence maternal menarche against menarche (0.388). Nutritional status, economic status, and exposure to pornographic media increase the incidence of early menarche. The highest risk factors for exposure to pornography resulted in 12.1 times the incidence of early menarche, economic status by 11.3 times, and nutritional status by 4.2 times. Strict supervision of mass media access and maintaining nutritional intake are necessary to prevent early menarche.
Hepatitis E virus
Authors: Pinazo Bandera JM , Toro Ortiz JP , Fernández García F 
Published: August 2022

Resumen

La infección por el virus de la hepatitis E ocasiona una importante morbimortalidad en pacientes de riesgo. Supone la hepatitis aguda más frecuente en algunos países, con una incidencia en aumento; sobre todo, en varios puntos geográficos de Europa. Los genotipos 1-2 suelen cursar en forma de hepatitis agudas epidémicas o endémicas relacionadas con grandes catástrofes y casos de hepatitis fulminante en gestantes. Los genotipos 3-4 son responsables de hepatitis aguda esporádicas y tienen riesgo de cronificar en pacientes inmunodeprimidos. La mayoría de las veces cursan de forma asintomática, existiendo riesgo de hepatitis aguda grave en embarazadas, fallo agudo sobre crónico en pacientes con hepatopatía basal y cronicidad en pacientes inmunodeprimidos. El VHE se caracteriza por una serie de manifestaciones extrahepáticas entre las que destacan las neurológicas (amiotrofia neurálgica bilateral y síndrome de Guillain Barré) y las renales. El diagnóstico se basa en técnicas moleculares en sangre o en heces. Una persistencia de la viremia de al menos 3 meses define la infección como crónica. La mayoría de los casos de hepatitis aguda E no requieren tratamiento específico, si bien es cierto que en casos de hepatitis aguda grave o hepatitis crónica se opta por tratamiento médico. En caso de cronicidad, si no se consigue el aclaramiento tras el descenso de medicación inmunosupresora, la ribavirina y el interferón pegilado se consideran los fármacos de elección. Como herramientas preventivas se recomienda una correcta higiene para evitar la transmisión así como abstenerse de comer carne cruda/poco cocinada de cerdos y similares.
Território Quarta Colônia sob o enfoque da Cesta de Bens e Serviços Territoriais
Authors: Froehlich José Marcos , Roque Aline Prestes 
Published: August 2022

Este artigo apresenta uma releitura histórica das iniciativas de desenvolvimento no território Quarta Colônia, a partir das noções teórico-metodológicas aportadas pelo enfoque da Cesta de Bens e Serviços Territoriais (CBST). O Território Quarta Colônia está localizado na região central do Rio Grande do Sul (Brasil) e se compõe de 9 municípios associados no Consórcio de Desenvolvimento Sustentável da Quarta Colônia (CONDESUS). O estudo recorreu à revisão de literatura como procedimento metodológico de base. O enfoque da CBST permitiu identificar dificuldades na governança territorial mais recente, com a tendência de que a renda de qualidade territorial seja apropriada cada vez mais por um conjunto restrito de atores.
Predicting student outcomes using digital logs of learning behaviors: Review, current standards, and suggestions for future work
Authors: Arizmendi Cara J. , Bernacki Matthew L. , Raković Mladen , Plumley Robert D. , Urban Christopher J. , Panter A. T. , Greene Jeffrey A. , Gates Kathleen M. 
Published: August 2022

AbstractUsing traces of behaviors to predict outcomes is useful in varied contexts ranging from buyer behaviors to behaviors collected from smart-home devices. Increasingly, higher education systems have been using Learning Management System (LMS) digital data to capture and understand students’ learning and well-being. Researchers in the social sciences are increasingly interested in the potential of using digital log data to predict outcomes and design interventions. Using LMS data for predicting the likelihood of students’ success in for-credit college courses provides a useful example of how social scientists can use these techniques on a variety of data types. Here, we provide a primer on how LMS data can be feature-mapped and analyzed to accomplish these goals. We begin with a literature review summarizing current approaches to analyzing LMS data, then discuss ethical issues of privacy when using demographic data and equitable model building. In the second part of the paper, we provide an overview of popular machine learning algorithms and review analytic considerations such as feature generation, assessment of model performance, and sampling techniques. Finally, we conclude with an empirical example demonstrating the ability of LMS data to predict student success, summarizing important features and assessing model performance across different model specifications.
Simulating the Legacy Survey of Space and Time Stellar Content with TRILEGAL
Authors: Dal Tio Piero , Pastorelli Giada , Mazzi Alessandro , Trabucchi Michele , Costa Guglielmo , Jacques Alice , Pieres Adriano , Girardi Léo , Chen Yang , Olsen Knut A. G. , Juric Mario , Ivezić Željko , Yoachim Peter , Clarkson William I. , Marigo Paola , Rodrigues Thaise S. , Zaggia Simone , Barbieri Mauro , Momany Yazan , Bressan Alessandro , Nikutta Robert , da Costa Luiz Nicolaci 
Published: August 2022

Abstract
We describe a large simulation of the stars to be observed by the Vera C. Rubin Observatory Legacy Survey of Space and Time (LSST). The simulation is based on the TRILEGAL code, which resorts to large databases of stellar evolutionary tracks, synthetic spectra, and pulsation models, added to simple prescriptions for the stellar density and star formation histories of the main structures of the Galaxy, to generate mock stellar samples through a population synthesis approach. The main bodies of the Magellanic Clouds are also included. A complete simulation is provided for single stars, down to the r = 27.5 mag depth of the coadded Wide–Fast–Deep survey images. A second simulation is provided for a fraction of the binaries, including the interacting ones, as derived with the BinaPSE module of TRILEGAL. We illustrate the main properties and numbers derived from these simulations, including: comparisons with real star counts; the expected numbers of Cepheids, long-period variables, and eclipsing binaries; the crowding limits as a function of seeing and filter; the star-to-galaxy ratios. Complete catalogs are accessible through the NOIRLab Astro Data Lab, while the stellar density maps are incorporated in the LSST metrics analysis framework.
La logistique et la ville. Questions environnementales et territoriales de la logistique urbaine
Authors: Dablanc Laetitia 
Published: August 2022

Les questions énergétiques et de pollution soulevées par les activités logistiques, qui comprennent l’ensemble des activités de transport et d’entreposage des marchandises, sont considérables. La logistique est l’une des activités dont les émissions de gaz à effet de serre ainsi que la consommation nette d’espace foncier augmentent le plus, même dans des scénarios prospectifs volontaristes. La logistique trouve par conséquent une place croissante dans les politiques territoriales et les stratégies environnementales, qu’elles soient publiques ou privées. Les travaux de la Chaire Logistics City, une équipe d’urbanistes, géographes et économistes de l’Université Gustave Eiffel, permettent d’examiner de plus près les mutations de la logistique urbaine, ses impacts territoriaux à plusieurs échelles, notamment dans sa dimension immobilière (les entrepôts, dont les nouveaux entrepôts du e-commerce) ; les innovations de la logistique urbaine ; et la dimension institutionnelle, réglementaire et politique de la mobilité des marchandises à travers les enjeux de pollution qu’elle pose aux villes.
Les sciences sociales sont nécessaires et complémentaires des sciences naturelles pour la recherche sur les changements climatiques
Authors: Fouqueray Timothée 
Published: August 2022

Climatologie, écologie, géologie : les sciences naturelles ont démontré l’existence et l’origine anthropique du dérèglement climatique. Pour autant, ce champ d’étude n’est pas l’apanage des seules sciences naturelles. En plus d’étudier la diversité de nos liens au monde vivant, la géographie, la sociologie, l’économie et autres disciplines sœurs permettent d’explorer des pistes complémentaires aux seules approches techniques pour répondre aux enjeux environnementaux. L’article présente les apports des sciences naturelles et des sciences sociales dans la compréhension et le déploiement de solutions d’atténuation et d’adaptation aux changements climatiques. Il décrit aussi une approche interdisciplinaire qui allie un jeu de rôles et des modélisations écologiques et climatiques afin de faciliter la prise de décision, la sensibilisation, et la diffusion de connaissances environnementales. Accessible à un lectorat formé en sciences naturelles ou en sciences sociales, l’article est ponctué d’exemples concrets tirés d’études classiques de la climatologie, de recherches contemporaines en sciences sociales, mais aussi de l’expérience de l’auteur – en particulier à travers Foster Forest, un jeu sérieux sur l’adaptation socio-économique de la foresterie aux changements climatiques.
A Roman ship scuttled near Salona in the Gulf of Kaštela, Croatia
Authors: Ruff David , Rossi Irena Radić , Pulak Cemal , Liphschitz Nili 
Published: August 2022

In 2002, the recovery of a 1000-litre perforated dolium in the Trstenik section of Kaštel Sućurac, near Split, Croatia, attracted the attention of archaeologists to significant Roman remains submerged near the shore. A return visit to the site in 2006 identified the outline of a wooden ship scuttled alongside a submerged wooden wall: in 2015, the ship was uncovered and labelled, recorded via photogrammetry and extensively sampled, then preserved in situ. Reconstruction determined the ship to be a flat-floored, ­mortise-and-tenon constructed ship, dated to approximately the late 1st century AD, suitable for the transport of heavy cargo.
Viking boats in medieval Russia from written and archaeological evidence
Authors: Sorokin Petr 
Published: August 2022

Mention of Viking vessels in Russia is rare and brief both in Russian letopis (chronicles) and in ancient Nordic literature. Foreign-language boat names were usually used in medieval Russian documents to designate foreign vessels, while local vessels, as well as their parts and rigging, practically always had local names. Archaeological data of boat finds from the territory of early medieval Russia includes elements of Scandinavian vessels and representations of Viking boats. They have been discovered in medieval layers of Russian towns along the main inland water routes connected with the Baltic from the mid-8th to early 11th centuries, and in boat graves. The Scandinavian boatbuilding tradition existed here in the period of intensive Russian-Scandinavian contacts during the Viking Age.
The Inhibitory Effects of Vanillin on the Growth of Melanoma by Reducing Nuclear Factor-κB Activation
Authors: Pourhadi Marjan , Ghasemi Ahmad , Abediny Reza , Haghjooy Javanmard Shaghayegh , Vaseghi Golnaz 
Published: August 2022

Background:
Melanoma is skin cancer, and the treatments are not efficient enough. Therefore, finding new drugs seems to be an essential need. Vanillin, which is extracted from vanilla seed, has anti-cancer effects by reducing nuclear factor-κB (NF). We explored the anti-tumor effects of vanillin in the melanoma model and its possible mechanism.

Materials and Methods:
In the MTT assay, mice melanoma cells (B16F10) were treated with vanillin (1, 2, 3, 4, 5 μg/mL) for 24 and 48 h. In an animal model, B16F10 was subcutaneously injected into C57BL/6 mice. After the development of tumors, the mice were treated with 50 and 100 mg/kg/day of vanillin for 10 days. The tumor size and expression level of NF-κB protein were measured.

Results:
In the MTT assay, vanillin in all concentrations significantly decreased B16F10 cell viability after 24 h incubation. The size of melanoma tumors was reduced in both doses 50 and 100 mg/kg/day in mice. NF-κB protein expression was decreased in the 100 mg/kg/day group in comparison with the control group.

Conclusion:
We found that vanillin by reducing NF-κB expression may have anti-tumor effects and reduced melanoma tumor size and cell viability.
Coinfection of pulmonary tuberculosis with other lower respiratory tract infections
Authors: Aldriwesh Marwh G. , Alaqeel Raghad A. , Mashraqi Aisha M. , Mashraqi Mutaib M. , Albdah Bayan A. , Alharbi Azzah S. 
Published: August 2022

BACKGROUND:
Little attention has been given to the development of lower respiratory tract infections (LRTIs) in patients with pulmonary tuberculosis (PTB) during their anti-tuberculosis (anti-TB) treatment and how that might affect patients’ health status. Here, the prevalence and etiologies of other LRTIs in a cohort of PTB patients were determined, and the clinical features and outcomes were described.

METHODS:
Adult patients with PTB between 2015 and 2020 were recruited and monitored during their anti-TB treatment for the presence of LRTIs. Clinical data were retrospectively collected from patients’ medical records.

RESULTS:
Data from 76 PTB patients (57 [75%] males) were reviewed. The median age was 61.0 (interquartile range 83.5–35.5) years, and other LRTIs were detected in 45 (59.2%) PTB patients. Of the 126 episodes of LRTIs, 84 (66.7%) were due to bacterial infections, 37 (29.4%) were due to fungal infections, and 5 (3.9%) were due to viral infections. The development of LRTIs was significantly more common in older (P = 0.012) and hypertensive patients with PTB (P = 0.019). Patients with PTB and LRTIs experienced significantly more frequent extrapulmonary infections (P = 0.0004), bloodstream infections (P = 0.001), intensive care unit stays (P = 0.001), and invasive mechanical ventilation use (P = 0.03) than patients who did not develop LRTI.

CONCLUSIONS:
The identification of host-related risk factors for LRTI development among patients with PTB could be used to develop a prediction model for LRTI development. Hence, initiating antimicrobials early, in parallel with appropriate anti-TB treatment, may mitigate PTB-related health and economic consequences.