bluuebunny/crossref_metadata_2025_split huggingface dataset:
The arbitration of trust disputes in New Zealand—a new frontier?
Authors: Anson-Holland James 
Published: April 2022

Abstract
Several provisions in New Zealand’s Trust Act seek to create a regime for the determination of trust disputes through alternative dispute resolution processes. At first blush, the regime seems to resolve the question of whether trust disputes are amenable to resolution through arbitration. However, on closer inspection, the regime gives rise to some real concerns about the recognition and enforceability of some awards, especially when those awards are rendered without the consent of all otherwise interested parties. This article discusses the regime and explores those concerns to highlight the perceived shortcomings.
Sham trusts and the requirement that a shamming intent be shared: Administrators of the Estate of Hanson v O’Leary and Ors
Authors: Arnull Thomas 
Published: April 2022

Abstract
In the recent case of Hanson, the Royal Court considered at length the principles applicable to claims that a trust is a sham and as such is void. The Court traced the case law through a number of recent developments. It reaffirmed the principle that, whereas a trustee's recklessness as to the terms of an apparent trust will constitute an intention that the assets would not be held on those apparent terms, recklessness will not suffice for the required intention to mislead third parties.
A comprehensive analysis of the floral transition in ma bamboo (Dendrocalamus latiflorus) reveals the roles of DlFTs involved in flowering
Authors: Fan Huijin , Zhuo Renying , Wang Huiyuan , Xu Jing , Jin Kangming , Huang Biyun , Qiao Guirong 
Published: April 2022

Abstract
Bamboo has a unique flowering characteristics of long and unpredictable vegetative period, which differs from annual herbs and perennial woody plants. In order to understand the molecular regulatory mechanism of bamboo flowering, a comprehensive study was conducted in ma bamboo (Dendrocalamus latiflorus Munro), including morphological, physiological and transcriptiome analyses. Differentially expressed genes related to the flowering pathway were identified by comparative transcriptome analysis. DlFT1, a homologous gene of FT/Hd3a, was significantly upregulated in flowering bamboo. Direct differentiation of spikelets from calli occurred and the downstream gene AP1 was upregulated in the transgenic bamboo overexpressing DlFT1. Transgenic rice overexpressing DlFT1 showed a strong early flowering phenotype. DlFT1 and DlTFL1 could interact with DlFD, and DlTFL1 delayed flowering. It is presumed that DlTFL1 plays an antagonistic role with DlFT1 in ma bamboo. In addition, the expression of DlFT1 was regulated by DlCO1, indicating that a CO-FT regulatory module might exist in ma bamboo. These results suggest that DlFT1 is a florigen candidate gene with conservative function in promoting flowering. Interestingly, the results have shown for the first time that DlFT2 can specifically interact with E3 ubiquitin ligase WAV3, while DlFT3 transcripts are mainly nonsense splicing. These findings provide better understanding of the roles of the florigen gene in bamboo and lay a theoretical basis for regulating bamboo flowering in the future.
Disseminated Congenital Tuberculosis in Neonates: A Case Series
Authors: Mane Sushant , Chopade Rajratna , Patil Aishwarya , Charania Kaif , Ganapathi Deepa , Pustake Manas 
Published: April 2022

Abstract
Congenital tuberculosis (CTB) is an uncommon yet, well-defined condition. CTB has a non-specific clinical presentation, making the diagnosis difficult. The rarity of CTB in neonates is due to the difficulty in distinguishing between congenital and postnatally acquired infection, and non-specific symptoms in the newborn, which are often misdiagnosed. Though it has a low incidence, it has significant mortality if the diagnosis is delayed. We are presenting two cases of CTB in newborns who showed signs of disease in the first few days of life. The diagnosis was suspected based on chest computed tomography, magnetic resonance imaging brain, cerebrospinal fluid studies, intrauterine growth restriction, non-response to standard treatment and a maternal history of active tuberculosis. These cases highlight the significance of having a high suspicion of CTB and timely treatment for better outcomes.
Integrative taxonomy of eared nightjars (Aves:Lyncornis) underscores the complementarity of morphology, vocalizations and DNA evidence
Authors: Sangster George , King Ben F , Irestedt Martin , Ericson Per G P 
Published: April 2022

AbstractThe eared nightjars (Lyncornis, formerly Eurostopodus) comprise six taxa distributed from southern India and Southeast Asia to Sulawesi. Species limits in this group have not been evaluated since 1940. In this study, we use three datasets (morphology, acoustics and mitochondrial DNA) to assess the taxonomic status of taxa in this genus. Multivariate analyses of vocalizations and phylogenetic analysis of mitochondrial DNA both revealed the presence of four major groups. Morphological analyses also revealed four major groups, but these agreed only in part with those identified by vocalizations and DNA. Lyncornis macrotis cerviniceps from mainland Southeast Asia and the isolated Lyncornis macrotis jacobsoni on Simeulue Island, off north-west Sumatra, differed by six diagnostic plumage characters, but could not be distinguished by their vocalizations or mitochondrial DNA. Conversely, Lyncornis macrotis macrotis from the Philippines and Lyncornis macrotis macropterus from Sulawesi differed diagnosably in song and by 5% sequence divergence but could not be diagnosed by plumage. We adopt an integrative approach and propose to recognize five monotypic species: Lyncornis temminckii, Lyncornis cerviniceps (synonym: Lyncornis bourdilloni), Lyncornis jacobsoni, Lyncornis macrotis and Lyncornis macropterus. Our study illustrates that taxonomic revisions based on single lines of evidence can underestimate diversity and underscores the importance of using multiple datasets in species-level taxonomy.
Towards completing the crocodile newts’ puzzle with all-inclusive phylogeographic resources
Authors: Dufresnes Christophe , Hernandez Axel 
Published: April 2022

AbstractCrocodile newts (Echinotriton and Tylototriton) are emblematic of the biodiversity of South-East Asia. In this study, we provide an account of their evolution, diversity and phylogeography based on mitochondrial (16.2 kb) and nuclear sequences (3.2 kb), combining barcoding data from nearly 1200 specimens collected over ~180 localities, representative of all lineages known to date. While phylogenies of nuclear data lacked resolution, the mitochondrial tree showed dynamic allopatric speciation that followed climate cooling during the last 10 million years, a pattern shared with many other tropical and subtropical amphibians. In crocodile newts, this implies weak dispersal and local adaptation as contributing factors of isolation, and was accompanied by macro- and micro-evolutionary changes in reproductive behaviours. Specifically, our resolved phylogeny of Tylototriton allowed the tracing of a major shift from conserved habits of terrestrial clutch-spawning towards more plastic strategies involving both aquatic and land spawning of single eggs. Using this framework, we then revised the taxonomy of crocodile newts by describing a new subgenus and two new species. Our study provides a basis to guide future phylogeographic, speciation and conservation research on these iconic amphibians.
Interdisciplinary and Innovative: A Nursing and Computer Science Collaboration to Create a Barcode Medication Administration System
Authors: Berndt Jodi , Ohmann Peter , Rahal Imad , Hoeschen Lindsey , Rothstein Andrew 
Published: April 2022

Abstract
Preventing medication errors remains a priority in nursing education. The implementation of Barcode Medication Administration (BCMA) systems is one strategy that has been used to reduce medication errors. Practice using BCMA in simulated settings may enhance the transfer of these skills to the clinical practice setting. However, the purchase of BCMA educational products available for nursing students can be cost prohibitive for many nursing programs. To overcome the barrier of cost, an interdisciplinary and innovative collaborative approach was used to create a fully functional low-cost BCMA system.
Improving Consistency in the Use of Sucrose With Comfort Measures During Minor Painful Procedures
Authors: Vykol Victoria , Wilson Janice , Goodwin Jana 
Published: April 2022

Background:
Inconsistent pain management practices can have negative physiologic and neurodevelopmental consequences in the neonate. Low rates of oral sucrose use with comfort measures for pain management during minor painful procedures were identified at a level III neonatal intensive care unit. Underutilization of pain management resources occurs despite the availability of evidence-based pain management interventions.

Purpose:
To improve consistency in the use of oral sucrose solution with comfort measures during peripheral intravenous catheter insertion attempts in the neonatal intensive care unit in patients greater than or equal to 32 0/7th weeks postmenstrual age.

Methods:
Quality improvement methods were used to implement an evidence-based procedural pain algorithm for minor painful procedures and optimize pain management processes over a 15-week period in a 26-bed, level III neonatal intensive care unit.

Results:
There was an increase in the average percentage of documented use of sucrose with comfort measures during peripheral intravenous catheter insertion attempts from 20% to 27%. There was a 41% increase in the average presence of a sucrose order indicated for procedural pain. There were improvements in staff knowledge of sucrose dosing and perceived behavior of staff after completing the education.

Implications for Practice and Research:
Procedural pain management should be used as a quality indicator and guidelines should be established with the support of key stakeholders in neonatal intensive care settings. Future projects should address barriers related to workflow and accessibility of sucrose, include other common needlestick procedures, and expand the role of parent participation in pain management practices.

Video Abstract available at:
https://journals.lww.com/advancesinneonatalcare/pages/video.aspx?v=60.
Treatment of VPI with Customized Pharyngeal Flaps: One Size Does Not Fit All
Authors: Boudiab Elizabeth M. , Peshel Emanuela C. , Ibrahim Yousef , Gupta Rohun , Chaiyasate Kongkrit , Shaheen Kenneth , Rontal Matthew , Thottam Prasad , Antonio Ysunza Pablo 
Published: April 2022

Background:
Failure of complete closure of the velopharyngeal sphincter results in velopharyngeal insufficiency (VPI), which may severely interfere with speech. The pharyngeal flap remains a common procedure for correcting VPI. We aimed to study whether customization of pharyngeal flaps using a dynamic preprocedural assessment can result in successful outcomes in the surgical treatment of VPI, despite variations in surgical technique.

Methods:
This is a retrospective review of patients between the ages 4 and 18 years old with VPI who underwent surgical correction by one of four surgeons at our institution. All four surgeons used a superiorly based pharyngeal flap (SBPF) with slight variations in operative technique. All patients also received an evaluation by the speech and language pathologist that included nasometry, multiplanar videofluoroscopy, and flexible videonasopharyngoscopy. Individualized preoperative planning was performed based on the findings.

Results:
In total, 158 patients (92%) demonstrated overall successful correction of VPI, defined by a normal post-operative mean nasalance. Thirteen patients (8%) presented with resonance improvement but persistent abnormal mean nasalance. The most common causes of failed VPI correction were inferior migration and/or shrinking of the pharyngeal flap. There was a nonsignificant association between surgical technique and unsuccessful corrections.

Conclusions:
The optimal surgical approach for performing pharyngeal flaps to correct VPI is individualized, customizing the procedure based on preoperative imaging. This study demonstrates that despite variations in surgical techniques for performing SBPF, high rates of success can be achieved when adequate surgical planning is based on imaging findings.
Correlation between bone mineral density of different sites and lumbar disc degeneration in postmenopausal women
Authors: Zhou Lin , Li Cheng , Zhang Hao 
Published: April 2022

Abstract
Osteoporosis and lumbar disc degeneration (LDD) have been common causes that make increasing patients suffer from different degrees of low back pain. At present, whether osteoporosis degenerates or protects disc is still controversial, and the correlation between hip bone mineral density (BMD) and LDD still remains unclear. Our study aims to analyze the correlation between BMD of different sites and LDD in postmenopausal women, and explore the potential pathophysiological mechanism of them.
One hundred ninety-five postmenopausal female patients were enrolled and divided into osteoporosis, osteopenia, and normal bone mass groups. Their BMD and lumbar spine magnetic resonance imaging were retrospectively analyzed. Two spine surgeons were selected to assess LDD according to Pfirrmann grading system.
Based on lumbar BMD, LDD of normal bone mass group was more severe than the other 2 groups in L1/2 and L2/3 segments (P < .05). Based on hip BMD, LDD of each disc from L1/2 to L5/S1 had no significant difference among the 3 groups (P > .05). Lumbar BMD (L1-L4) was positively correlated with corresponding degree of LDD (L1/2-L4/5) (P < .05), whereas there was no correlation between hip BMD and degree of LDD (P = .328).
There is a positive correlation between lumbar BMD and LDD in postmenopausal women, which is more obvious in the upper lumbar spinal segments (L1, L2). However, there is no correlation between hip BMD and LDD, suggesting that in postmenopausal women with lumbar degenerative disease, hip BMD is more suitable for the diagnosis of osteoporosis.
The efficacy and safety of massage therapy as an adjuvant in the treatment of hypoxic ischemic encephalopathy in neonates
Authors: Meizhuang Wang , Xu Haizhu , Chen Youhong 
Published: April 2022

Abstract

Background:
Neonatal hypoxic-ischemic encephalopathy (HIE) has become a major problem that endangers the life and health of newborns. It is the most serious complication after neonatal asphyxia with a high mortality rate. Even survivors of HIE would suffer permanent neurological developmental impairment that seriously affects the growth and development in the future. Previous studies have shown that massage therapy can improve the prognosis of neonatal HIE. However, the efficacy of massage therapy on the growth, development, and sleep in neonates with HIE reported by various studies is inconsistent, which will be thoroughly assessed in this meta-analysis.

Methods:
Randomized controlled trials of massage therapy on the growth, development, and sleep neonates with HIE published before February 2022 will be retrieved from the PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wan Fang Database, Chinese Biomedical Literature Database, VIP Database for Chinese Technical Periodicals, and Clinical Trial Register. Literature selection, data extraction, risk of bias assessment, and meta-analyses will be independently completed by 2 researchers. Meta-analysis will be performed by using RevMan5.4.

Results:
The results of this meta-analysis will be submitted to a peer-reviewed journal for publication.

Conclusion:
This systematic review provides a high-quality synthesis to assess the effect of massage therapy on growth, development, and sleep in neonates with HIE.

OSF registration number:
DOI 10.17605/OSF.IO/G9WXN.
Blood Component Requirements and Erythrocyte Transfusion and Mortality Related to Hemoglobin Deficit in Phase III Trial of Hemoglobin-Based Oxygen Carrier: HBOC-201
Authors: Jahr Jonathan S. , Williams John P. 
Published: April 2022

Background:
Hemoglobin-based oxygen carriers (HBOCs) may cause coagulopathy, changes in total hemoglobin (THb), and affect mortality. Low total hemoglobin concentrations [THb] during hemorrhage may worsen outcomes.

Study Question:
The database of the Hemopure HEM-0115 phase III trial was queried to determine the use of platelets, plasma, or cryoprecipitate and compare transfusion requirements and coagulation studies between patients randomized to erythrocyte transfusion or HBOC-201 infusion. Modeling of hemoglobin (Hb) changes produced by HBOC-201, erythrocyte, and blood product administration were related to [THb], coagulopathy, and mortality.

Data Sources:
Hemopure HEM-0115 phase III trial database.

Study Design:
Retrospective and Novel Hemoglobin Deficit Formulas Tested Against Existing Database.

Results:
The HBOC-201 database (n = 688) demonstrated less than 6% of subjects in both groups were administered non-Hb containing blood products (fresh frozen plasma, platelets, or cryoprecipitate) and low rates of coagulopathies in both erythrocyte and HBOC-201 arms. There were no differences in mortality in elective orthopedic patients administered up to 10 bags HBOC-201 (equivalent to 3 units erythrocytes). Low total [Hb] and lack of adequate oxygen carrying capacity was found to be an independent predictor of morbidity/mortality.

Conclusions:
The elective use of HBOC-201 for orthopedics versus erythrocytes demonstrated low incidence of blood product requirements in both cohorts and no differences in mortality up to the HBOC-201 equivalent of 3 units erythrocytes. High total Hb may be important to maintain in acute hemorrhage and [Hb] deficit, whereas later in recovery might not be as crucial. Future trauma trials may benefit from the use of HBOC-201 containing 13 g/dL in prehospital management, when erythrocytes are commonly not available.
Chief Nursing Officers
Authors: Monroe Martha , Davies Claire C. , Beckman Dee , Cantrell Donita , Brockopp Dorothy 
Published: April 2022

OBJECTIVE
The purpose of this study was to describe the experience of chief nursing officers (CNOs), including leadership strategies that they developed as they encountered the administrative challenges posed by COVID-19.

BACKGROUND
The COVID-19 pandemic required CNOs to make difficult decisions and to support nursing staff as they cared for critically ill and dying patients, and therefore, they experienced intense stress during a pandemic of a highly infectious disease. Understanding the challenges that CNOs faced in this crisis will help hospitals and CNOs to better prepare for the future.

METHODS
Using a descriptive qualitative approach, we conducted interviews with 9 CNOs from hospitals across the United States. The goal of the interviews was to develop an understanding of the difficulties that these CNOs encountered during the COVID-19 pandemic and their emotional response to the challenging situations.

RESULTS
Themes of frustration, heartbreak, and feeling overwhelmed, exhausted, and helpless were revealed. In addition, pride in being a nurse was expressed.

CONCLUSION
Themes revealed in this study suggested intentional leadership strategies that would be useful in future healthcare crises.
Leadership Implications Related to Bullying and Intent to Leave Among Licensed Practical Nurses
Authors: Filipova Anna A. 
Published: April 2022

OBJECTIVE
This study examines the relationship between bullying and intent to leave among a sample of LPNs as mediated by exhaustion, job satisfaction, and organizational commitment.

BACKGROUND
Bullying incidents may negatively impact the well-being, commitment, and retention for LPNs.

METHODS
A cross-sectional survey design was used. A total of 168 questionnaires (19.65% response rate) were analyzed, performing Pearson correlation, mediation, and hierarchical regression tests.

RESULTS
LPNs reported a relatively high score on exhaustion and were somewhat committed to their organization. They were fairly satisfied with the job and unlikely to leave it. The model explained 72% of the variance in intent to leave, with commitment, exhaustion, and bullying being the strongest correlates.

CONCLUSIONS
Nursing leadership needs to implement antibullying language in policies, institute communication and self-leadership trainings, model authentic leadership, and foster ethical climates to support the retention of LPNs.
An observational study of centrally facilitated pain in individuals with chronic low back pain
Authors: Georgopoulos Vasileios , Akin-Akinyosoye Kehinde , Smith Stephanie , McWilliams Daniel F. , Hendrick Paul , Walsh David A. 
Published: April 2022

Abstract

Introduction:
Central pain facilitation can hinder recovery in people with chronic low back pain (CLBP).

Objectives:
The objective of this observational study was to investigate whether indices of centrally facilitated pain are associated with pain outcomes in a hospital-based cohort of individuals with CLBP undertaking a pain management programme.

Methods:
Participants provided self-report and pain sensitivity data at baseline (n = 97) and again 3 months (n = 87) after a cognitive behavioural therapy–based group intervention including physiotherapy. Indices of centrally facilitated pain were pressure pain detection threshold, temporal summation and conditioned pain modulation at the forearm, Widespread Pain Index (WPI) classified using a body manikin, and a Central Mechanisms Trait (CMT) factor derived from 8 self-reported characteristics of anxiety, depression, neuropathic pain, fatigue, cognitive dysfunction, pain distribution, catastrophizing, and sleep. Pain severity was a composite factor derived from Numerical Rating Scales. Cross-sectional and longitudinal regression models were adjusted for age and sex.

Results:
Baseline CMT and WPI each was associated with higher pain severity (CMT: r = 0.50, P < 0.001; WPI: r = 0.21, P = 0.04) at baseline and at 3 months (CMT: r = 0.38, P < 0.001; WPI: r = 0.24, P = 0.02). High baseline CMT remained significantly associated with pain at 3 months after additional adjustment for baseline pain (β = 2.45, P = 0.04, R
2 = 0.25, P < 0.0001). Quantitative sensory testing indices of pain hypersensitivity were not significantly associated with pain outcomes at baseline or at 3 months.

Conclusion:
Central mechanisms beyond those captured by quantitative sensory testing are associated with poor CLBP outcome and might be targets for improved therapy.