bluuebunny/crossref_metadata_2025_split huggingface dataset:
Residual Hip Dysplasia in Children With Unilateral Hip Dislocation—Does Side Matter?
Authors: Lin Hsin-Ying , de Vos-Jakobs Suzanne , Westerbos Stijn , Reijman Max 
Published: September 2022

Background:
Developmental dysplasia of the hip (DDH) is the most common musculoskeletal abnormality in infants and young children. Despite the fact that the left hip is most frequently affected, literature and clinical experience suggest a poorer outcome for right-sided hip dislocation in DDH. On the basis of this hypothesis, we studied the outcomes (residual dysplasia, number of surgeries, and complication rate) of right-sided unilateral hip dislocation in comparison with left-sided unilateral hip dislocation in DDH up to 8 years follow-up.

Methods:
We identified all patients with unilateral hip dislocation at Erasmus MC Sophia Children’s Hospital from 2002 to 2012, diagnosed with DDH before the age of 1 year and with a minimum follow-up of 8 years. The primary outcome was residual dysplasia (based on an acetabular index (AI) >18 degrees and center-edge angle of Wiberg (CEA) <15 degrees) at the age of 8 years. Secondary outcome measures were residual dysplasia at the ages of 1, 2, and 5 years, successful surgical reduction rates, additional surgery, and complication rates.

Results:
Out of a consecutive series of 555 patients, 298 could be included (17 males; median age at diagnosis 4.0 [IQR 3.0 to 5.5] months): 107 patients (35.9%) had right-sided unilateral hip dislocation. There was no significant difference in residual dysplasia between the unilateral left-sided and unilateral right-sided hip dislocation groups, respectively, at 1-year follow-up (34.0% vs. 24.2%, P=0.107), 2-year follow-up (74.1% vs. 70.1%, P=0.565), 5-year follow-up (74.1% vs. 66.2%, P=0.261), and 8-year follow-up (65.3% vs. 53.8%, P=0.199). There was no significant difference in surgical interventions between the left-sided and right-sided hip dislocation groups, respectively: additional surgical reduction (14.7% vs. 15.0%, P=0.945) and additional surgery for residual dysplasia (8.9% vs. 10.3%, P=0.695). There was no significant difference in complication rate between the unilateral left-sided and unilateral right-sided hip dislocation groups, respectively: avascular necrosis (19.4% vs. 15.9%, P=0.454) and redislocation (11.5% vs. 9.3%, P=0.561).

Conclusions:
The results of our study suggest that in patients with DDH, unilateral right-sided hip dislocation does not have poorer outcomes compared with unilateral left-sided hip dislocation during an 8-year follow-up.

Level of Evidence:
Level III – retrospective follow-up study.
OPTICAL COHERENCE TOMOGRAPHY FEATURES IN IDIOPATHIC NONINFECTIOUS INTERMEDIATE, POSTERIOR, OR PANUVEITIS
Authors: Felfeli Tina , Eshtiaghi Arshia , Tai Felicia , Batawi Hatim , Rhee Jess , Kryshtalskyj Michael , Dzulynsky Kira , Bakshi Nupura K. , Derzko-Dzulynsky Larissa A. 
Published: September 2022

Purpose:
To characterize optical coherence tomography features in patients with idiopathic intermediate, posterior, or panuveitis.

Methods:
This is a retrospective case series of all consecutive cases of idiopathic intermediate, posterior, or panuveitis at four tertiary care centres between 2010 and 2021.

Results:
A total of 94 eyes (55 patients) were followed for an average duration of 29.8 (SD 21) months. The median central macular thickness was 284 µm at baseline and 267 µm at last follow-up. At baseline and last follow-up, respectively, 24% and 20% of uveitic eyes had intraretinal fluid, 12% and 1% subretinal fluid, and 43% and 54% epiretinal membrane. In addition, ellipsoid zone abnormalities on en-face were noted in 34% and 19% of cases at baseline and last follow-up, respectively. The baseline median visual acuity was significantly lower among cases with ellipsoid zone en-face slab abnormalities compared with those without (0.2 logarithm of minimum angle of resolution [interquartile range: 0–0.6] vs. 0.1 logarithm of minimum angle of resolution [interquartile range: 0–0.3], P = 0.0051).

Conclusion:
With initiation of treatment, the central macular thickness, intraretinal fluid, subretinal fluid, and ellipsoid zone en-face abnormalities improved over time, whereas the number of cases with epiretinal membrane increased among eyes with idiopathic intermediate, posterior, and panuveitis. Presence of ellipsoid zone en-face abnormalities at presentation may be associated with worse visual acuity.
P-glycoprotein, FK-binding Protein-12, and the Intracellular Tacrolimus Concentration in T-lymphocytes and Monocytes of Kidney Transplant Recipients
Authors: Udomkarnjananun Suwasin , Francke Marith I. , Dieterich Marjolein , van De Velde Daan , Litjens Nicolle H.R. , Boer Karin , De Winter Brenda C.M. , Baan Carla C. , Hesselink Dennis A. 
Published: September 2022

Background
. Transplant recipients may develop rejection despite having adequate tacrolimus whole blood predose concentrations (C0). The intra-immune cellular concentration is potentially a better target than C0. However, little is known regarding intracellular tacrolimus concentration in T-lymphocytes and monocytes. We investigated the tacrolimus concentrations in both cell types and their relation with the expression and activity of FK-binding protein (FKBP)-12 and P-glycoprotein (P-gp).

Methods
. T-lymphocytes and monocytes were isolated from kidney transplant recipients followed by intracellular tacrolimus concentration measurement. FKBP-12 and P-gp were quantified with Western blot, flow cytometry, and the Rhodamine-123 assay. Interleukin-2 and interferon-γ in T-lymphocytes were measured to quantify the effect of tacrolimus.

Results
. Tacrolimus concentration in T-lymphocytes was lower than in monocytes (15.3 [8.5–33.4] versus 131.0 [73.5–225.1] pg/million cells; P < 0.001). The activity of P-gp (measured by Rhodamine-123 assay) was higher in T-lymphocytes than in monocytes. Flow cytometry demonstrated a higher expression of P-gp (normalized mean fluorescence intensity 1.5 [1.2–1.7] versus 1.2 [1.1–1.4]; P = 0.012) and a lower expression of FKBP-12 (normalized mean fluorescence intensity 1.3 [1.2–1.7] versus 1.5 [1.4–2.0]; P = 0.011) in T-lymphocytes than monocytes. Western blot confirmed these observations. The addition of verapamil, a P-gp inhibitor, resulted in a 2-fold higher intra-T-cell tacrolimus concentration. This was accompanied by a significantly fewer cytokine-producing cells.

Conclusions
. T-lymphocytes have a higher activity of P-gp and lower concentration of the FKBP-12 compared with monocytes. This explains the relatively lower tacrolimus concentration in T-lymphocytes. The addition of verapamil prevents loss of intracellular tacrolimus during the cell isolation process and is required to ensure adequate intracellular concentration measurement.
New forms of ecological knowledge acquisition for freshwater mussels’ conservation
Authors: Ferreira-Rodríguez Noé 
Published: September 2022

AbstractFreshwater mussels are of recognized importance for ecosystem functioning, for the provision of ecosystem services, and for human well-being. Whether people are more concerned about freshwater mussels has a large role to play in promoting and supporting political decisions that protect their habitat. A pilot study was performed in the Midwest of the United States to evaluate the awareness people have about freshwater mussels both native and non-native. Using semi-structured face-to-face interviews, I explore whether ecological knowledge is still in place in the community, and what the relationship is between knowledge, age and urbanization. Multinomial logistic regression has shown that population size and age class are significant predictors of ecological knowledge. Present results suggest that common channels of ecological knowledge transmission have been interrupted long ago. As a result, local ecological knowledge is being substituted by modern ecological knowledge. Nevertheless, new processes of ecological knowledge acquisition emerge. Under this scenario, future management prospects would rely on state institutions which are implementing alternative dissemination pathways in modern socio-ecological systems.
Measuring digital transformation in higher education institutions – content validity instrument
Authors: Castro Benavides Lina María , Tamayo Arias Johnny Alexander , Burgos Daniel , Martens Alke 
Published: September 2022

PurposeThis study aims to validate the content of an instrument which identifies the organizational, sociocultural and technological characteristics that foster digital transformation (DT) in higher education institutions (HEIs) through the Delphi method.Design/methodology/approachThe methodology is quantitative, non-experimental, and descriptive in scope. First, expert judges were selected; Second, Aiken'sVcoefficients were obtained. Nine experts were considered for the validation.FindingsThis study’s findings show that the instrument has content validity and there was strong consensus among the judges. The instrument consists of 29 questions; 13 items adjusted and 2 merged.Originality/valueA novel instrument for measuring the DT at HEIs was designed and has content validity, evidenced by Aiken'sVcoefficients of 0.91 with a 0.05 significance, and consensus among judges evidenced by consensus coefficient of 0.81.
Evolution model and quantitative assessment of risk network in housing construction accidents
Authors: Cheng Lianhua , Cao Dongqiang 
Published: September 2022

PurposeClarifying the risk evolution mechanism of housing construction for work-safety management is essential. Existing studies have inadequately discussed the risk-accumulation process in housing construction. Therefore, this study aimed to use the complex network theory and risk allocation mechanisms to explore the evolution of risk factors.Design/methodology/approachThe authors analysed a database of housing construction accidents in China from 2015 to 2020 to identify risk factors. Moreover, the causal relationship between risk factors was determined through a systematic analysis of the logical sequence of risk factors. A complex network was used to construct a risk network for housing construction accidents (RNHCA).FindingsThe risk matrix method was used to define the factor risk threshold, and a risk value was assigned based on the correlation between risk factors. This contributes to the examination of the evolution mechanism of risk networks in the process of risk factor transmission. The case verification results show that the RNHCA quantitative assessment model can better evaluate the system risk status of housing construction accidents. Furthermore, this model can identify the key risk factors and risk chains with high risk in the evolution of the risk network.Research limitations/implicationsAccident investigation reports need to be classified and processed to analyse the evolution law of risk networks under different scales of construction project, such as high-rise buildings, middle-rise buildings, and low-rise buildings.Practical implicationsThis study clarified the risk evolution process of complex systems in housing construction and provided a new method for analysing accidents.Originality/valueThis study clarifies the risk value allocation of risk factors in the transmission process and reveals the process of risk factor evolution in housing construction. This study explains the individual risk factors that form a systemic risk through the transmission chain. Moreover, this paper clarified the transformation relationship between system risk and accidents. The paper also provided a new perspective for risk analysis.
Governmental accounting and budgeting in Malta and Poland – a different dance to the same tune
Authors: Kowalczyk Magdalena , Caruana Josette 
Published: September 2022

PurposeThis paper compares governmental accounting and budgeting in two European Union (EU) member states, analysing the developments in each country as to how they “fit” into the EU's harmonization project and the push towards the implementation of accrual accounting compliant with the International Public Sector Accounting Standards (IPSAS).Design/methodology/approachAn explanatory multiple case study is used to describe the structures and changes in governmental systems (accounting and budgetary) in Malta and Poland. The methodology takes a qualitative interpretative approach, examining the underlying legislations and related ministerial publications as secondary sources.FindingsFocusing on the output from financial accounting and budgetary systems, the results illustrate how organizations respond in a different manner to similar institutional pressures. In particular, Poland shows no inclination to adopt the IPSAS, but emerges with a sophisticated budgeting system while Malta is more focused on developing its financial reporting in line with the IPSAS. The theoretical lens highlights that while both countries tend towards pragmatic legitimacy, Poland appears more inclined towards exchange legitimacy, and Malta is more subject to influence legitimacy.Research limitations/implicationsAt a practical level, this study should be read by public sector accounting standard setters. It illustrates how EU member states are engaging with the IPSAS, emphasizing the ambitious nature of the EU's harmonization project, in spite of the structural legitimacy that the EU institution emanates.Originality/valuePrevious comparative international governmental accounting studies have examined accounting reform processes and developed or applied various theoretical models to try to understand the process. This study looks at the output from such reform processes. The two countries are seemingly experiencing the same type of pressures exerted by the demands of EU membership. However, the translation of the same external macro-forces at macro-level to micro (organizational)-level results in different compliance with the desired harmonization of governmental accounting systems.
The role of technological absorption capacity, enviropreneurial orientation, and green marketing in enhancing business' sustainability: evidence from fast-moving consumer goods in Tanzania
Authors: Ismail Ismail Juma 
Published: September 2022

PurposeGiven current global environmental concerns, traditional marketing and entrepreneurial practices of small businesses are considered ineffective. This is because sustainability requires the involvement of social, economic, and environmental dimensions. This study, therefore, aims at analyzing the moderating effect of technological absorptive capacity (TEOC) in the relationship between green marketing mix (GMX), enviropreneurial orientation (ENVO) and the sustainability of small businesses (SUST).Design/methodology/approachThis study is cross-sectional. This study used data from 243 fast-moving consumer goods (FMCG) industries, such as food and beverages, cleaning products, office supplies, cosmetics, and toiletries. Structural equation mdeling (SEM) and the PROCESS macro test were employed during data analysis.FindingsThe findings suggest that GMX and ENVO are significant determinants of SUST. Also, TEOC is a significant moderator of GMX, ENVO, and SUST.Research limitations/implicationsThis study used owner-managers as the respondents; future studies can use employees and customers to find out how small businesses involve other stakeholders in designing GMX and ENVO and adopting technologies for business sustainability and adopting technologies for business sustainability.Practical implicationsThe study has practical implications for policymakers and owner-managers, especially on the significant contributions of GMX, ENVO, and TEOC to business sustainability.Originality/valueDepending only on traditional marketing and entrepreneurial practices is no longer a reliable technique for business sustainability. By bringing environmental aspects into business management through a green marketing mix and enviropreneurial orientation, the study provides a unique and new way of thinking about sustainability. Also, the study adds knowledge to the body of literature through a moderating effect of TEOC in the relationship between GMX, ENVO, and SUST.
A case study of implementing interprofessional education in care home settings
Authors: Stephens Melanie , Hubbard Lydia , Kelly Siobhan , Clark Andrew , Chesterton Lorna 
Published: September 2022

Purpose
The purpose of this paper is to report on an interprofessional (IPE) student training scheme recently conducted in three care homes across the Northwest of England. The intervention was designed as a feasibility study to explore the impacts such schemes have on residents, students and care home staff. Additional lessons emerged that contribute to the design and direction of future IPE initiatives in other care homes and care settings.

Design/methodology/approach
This case study outlines how the intervention was designed and implemented and the findings from its evaluation. This paper uses Biggs’ (1993) presage–process–product framework to evaluate the process of setting up care homes as a site of collaborative learning.

Findings
Collaborative working between stakeholders is necessary for the successful implementation of IPE in care home settings. The process is complex and requires communication and commitment across all levels of engagement. For this model to grow and have a beneficial impact on older people’s lives, there are layered factors to consider, such as the socio-political context, the characteristics of the individuals who participate and diverse approaches to learning.

Research limitations/implications
This case study reports the subjective views of the research collaborators. While this raises the potential for bias, it presents an “insider” perspective of the research process and offers learning that might be beneficial in efforts to run future IPE training schemes.

Originality/value
To the best of the authors’ knowledge, no other research studies or published interventions have been identified that explicitly address the experiences of implementing an IPE training scheme in UK care home settings. This paper will therefore be useful to academic researchers, individuals managing student placements and to health and social care staff who wish to learn about of the value of IPE learning schemes.
Race, Nutrition and Empire: Domestic Reform and Japanese Immigrants in Territorial‐Era Hawaiʻi
Authors: Koikari Mire 
Published: September 2022

AbstractThe article examines the rise of domestic science in territorial‐era Hawaiʻi. At the dawn of the twentieth century, as the Pacific became a new frontier, ‘manifest domesticity’ emerged as a prominent dynamic, and home economics became linked to empire‐building. At the centre of this phenomenon was Carey D. Miller, a self‐proclaimed ‘pioneer’ whose pursuit of nutritional research and reform was inseparable from American expansionism. The Pacific was complex terrain, however. Japan also was asserting influence in the region, dispatching emigrant workers and pursuing its own ambitions of settler colonialism in which the home and homemaking, including dietary reform, also assumed exceptional significance.
The value of a simple sonographic screening test for placenta accreta spectrum prediction: A case–control study
Authors: Aiob Ala , Gaziyev Ziyada , Mikhail Susana Mustafa , Wolf Maya , Lowenstein Lior , Odeh Marwan 
Published: September 2022

AbstractBackgroundPlacenta accreta spectrum (PAS) represents life‐threatening conditions; however, early diagnosis reduces complications and mortality rates.AimsTo develop and evaluate the accuracy of a simple sonographic screening test for PAS prediction.Materials and MethodsA retrospective case–control study of 481 women with singleton pregnancies at 28 weeks or later, with a scarred uterus or placenta praevia, who underwent sonographic testing for PAS detection during 2010–2020. We compared demographic and sonographic features, and delivery outcomes between women who were and were not confirmed to have a PAS condition at delivery. We evaluated the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and predictive probability for the sonographic screening model.ResultsAmong all the women with at least one sonographic sign (large lacunae or loss of clear zone), the odds ratio (OR) of PAS was 21.7 (95% CI, 16.7–70.4), among those with placenta praevia (and at least one sonographic sign), the OR was 41.9 (95% CI, 15.8–111). For the screening model (the combinations of placental location (major or minor placenta praevia) with at least one sonographic sign (large lacunae or loss of clear zone)), sensitivity, specificity, PPV, NPV and predicted probability were 94.9% (85.8–98.9%), 91.5% (88.4–93.9%), 60.9% (50.1–70.9%), 99.2% (97.7–99.8%) and 92.3%, respectively.ConclusionsA combination of simple ultrasound signs for PAS screening may be highly effective for prenatal assessment and prediction of placenta accreta. This screening test can be carried out as routine pregnancy follow‐up for women with risk factors for PAS.
Telemedicine versus face‐to‐face follow up in general surgery: a randomized controlled trial
Authors: Fink Teagan , Chen Qianyu , Chong Lynn , Hii Michael W. , Knowles Brett 
Published: September 2022

AbstractBackgroundTelemedicine provides healthcare to patients at a distance from their treating clinician. There is a lack of high‐quality evidence to support the safety and acceptability of telemedicine for postoperative outpatient follow‐up. This randomized controlled trial—conducted before the COVID‐19 pandemic—aimed to assess patient satisfaction and safety (as determined by readmission, reoperation and complication rates) by telephone compared to face‐to‐face follow‐up after uncomplicated general surgical procedures.MethodsPatients following laparoscopic appendicectomy or cholecystectomy and laparoscopic or open umbilical or inguinal hernia repairs were randomized to a telephone or face‐to‐face outpatient clinic. Patient demographics, perioperative details and postoperative outcomes were compared. Patient satisfaction was assessed via a standardized Likert‐style scale.ResultsOne hundred and twenty‐three patients were randomized over 12 months. Mean consultation times were significantly shorter for telemedicine than face‐to‐face clinics (telemedicine 10.52 ± 7.2 min, face‐to‐face 15.95 ± 9.96 min, P = 0.0021). There was no difference between groups in the attendance rates, nor the incidence or detection of postoperative complications. Of the 58 patients randomized to the telemedicine arm, 40% reported high, and 60% reported very high satisfaction with the method of clinic follow‐up.ConclusionTelemedicine postoperative follow‐up is safe and acceptable to patients and could be considered in patients undergoing uncomplicated benign general surgery.