bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of spinel ZnMn2O4 particles on the dielectric performance of PVDF‐based composites
Authors: Yu Yang , Wang Xiao‐Ming , Bu De‐Chao , Feng Yu , Chi Ming‐He 
Published: September 2022

AbstractSpinel ZnMn2O4 are widely used in lithium batteries, sensors, and catalysis due to its electrical and magnetic properties. However, the influence of the resistive switching effect on the dielectric properties of the polymer matrix induced by ZnMn2O4 has not been investigated in depth. In this study, spinel ZnMn2O4 powders were synthesized via the hydrothermal method, and ZnMn2O4/PVDF composites were prepared for research the influence of ZnMn2O4 particles on dielectric performance of PVDF‐based composites. The existence of ZnMn2O4 particles improves the dielectric constant slightly, while enhances the breakdown strength of composites significantly. The maximum value of breakdown strength achieved in composite with 10 wt% ZnMn2O4 is 108 kV/mm, which is five times larger than that of undoped PVDF. The enhanced dielectric properties are attributed to the quasi‐Coulomb blockade effect induced by the resistive switching effect of ZnMn2O4 particles under applied electric field. The results presented in this work indicate the promising of ZnMn2O4 particles in dielectric and insulating composites.
Technically successful fetal aortic valvuloplasty acutely improves left heart output
Authors: Asrani Priyanka P. , Gellis Laura A. , Schidlow David , Callahan Ryan , Porras Diego , Wilkins‐Haug Louise , Guseh Stephanie , Tworetzky Wayne , Friedman Kevin G. 
Published: September 2022

Key pointsWhat is known?

Fetal aortic valvuloplasty (FAV) may avert the progression of mid‐gestation aortic stenosis (AS) to Hypoplastic left heart syndrome (HLHS) in a subset of fetus.

What this study adds?

Novel assessment of flow through the mitral valve (MV) to estimate left heart output in fetus with AS after a FAV.
SNP discovery in proso millet (Panicum miliaceum L.) using low‐pass genome sequencing
Authors: Khound Rituraj , Sun Guangchao , Mural Ravi V. , Schnable James C. , Santra Dipak K. 
Published: September 2022

AbstractDomesticated ~10,000 years ago in northern China, Proso millet (Panicum miliaceum L.) is a climate‐resilient and human health‐promoting cereal crop. The genome size of this self‐pollinated allotetraploid is 923 Mb. Proso millet seeds are an important part of the human diet in many countries. In the USA, its use is restricted to the birdseed and pet food market. Proso millet is witnessing gradual demand in the global human health and wellness food market owing to its health‐promoting properties such as low glycemic index and gluten‐free. The breeding efforts for developing improved proso millet cultivars are hindered by the dearth of genomic resources available to researchers. The publication of the reference genome and availability of cost‐effective NGS methodologies could lead to the identification of high‐quality genetic variants, which can be incorporated into breeding pipelines. Here, we report the identification of single‐nucleotide polymorphisms (SNPs) by low‐pass (1×) genome sequencing of 85 diverse proso millet accessions from 23 different countries. The 2 × 150 bp Illumina paired‐end reads generated after sequencing were aligned to the proso millet reference genome. The resulting sequence alignment information was used to call SNPs. We obtained 972,863 bi‐allelic SNPs after quality filtering of the raw SNPs. These SNPs were used to assess the population structure and phylogenetic relationships among the accessions. Most of the accessions were found to be highly inbred with heterozygosity ranging between .05 and .20. Principal component analysis (PCA) showed that PC1 (principal component) and PC2 explained 19% of the variability in the population. PCA also clustered all the genotypes into three groups. A neighbor‐joining tree clustered the genotypes into four distinct groups exhibiting diverse representation within the population. The SNPs identified in our study could be used for molecular breeding and genetics research (e.g., genetic and association mapping, and population genetics) in proso millet after proper validation.
Racial harmony and sexual violence: Uneven regulation and legal protection gaps for influencers in Singapore
Authors: Radics George , Abidin Crystal 
Published: September 2022

AbstractDrawing on a multi‐year ethnographic study of influencers in Singapore and analyses on frameworks regulating racial harmony and sexual violence, this paper adopts approaches from anthropology, cultural studies, and socio‐legal studies to illustrate how the law heavily regulates certain influencers while failing to protect others. This spans across governance from the “state” through government interventions and introduction of formal law, governance in the “industry” through sector‐based guidelines and best practice recommendations, and governance in the “vernacular” from peer surveillance and the court of public opinion in civil society. Through mixed qualitative methodologies including traditional and digital participant observation, content analysis, archival research, document survey, and case study files, this paper aims to locate the current terms and boundaries of influencer governance and regulation in the verticals of “race & culture” and “sex & safety.” In “race & culture,” we consider how the majority‐race Chinese influencers and minority‐race Malay and Indian influencers are differently policed by the three tiers of governance, and experience uneven consequences. This includes commentary that is overtly racist, poor stereotypes that perpetuate everyday racism, and parody content that calls out systemic racism. In “sex & safety,” we consider how sexual harassment and assault are regulated in the industry. This includes the underbelly of the industry where some prominent influencers‐cum‐managers have been accused of sexual grooming and advances as part of their recruitment processes. It highlights how when women are provided an anonymous space to discuss sexual harassment, a tidal wave of stories emerge, leading to doxxing and the potential for vigilante justice. It also reveals how LGBT influencers and sexual offenders are policed more harshly, while sexual harassment against women take place without repercussion even when revealed. We end with a consideration of the state of influencer wellbeing and welfare in the industry, and the place of the law in regulating longstanding and emergent issues.
The effects of rutin flavonoid supplement on glycemic status, lipid profile, atherogenic index of plasma, brain‐derived neurotrophic factor (BDNF), some serum inflammatory, and oxidative stress factors in patients with type 2 diabetes mellitus: A double‐blind, placebo‐controlled trial
Authors: Bazyar Hadi , Moradi Leila , Zaman Ferdows , Zare Javid Ahmad 
Published: September 2022

AbstractThis study aimed to investigate the effects of rutin flavonoid in type 2 diabetes mellitus (T2DM) patients. In this trial (double‐blind, placebo‐controlled), 50 T2DM patients (supplement, n = 25 and placebo, n = 25) were randomized and supplemented with 500 mg rutin or placebo per day for 3‐months. At the beginning and at the end of the study, metabolic parameters including fasting blood glucose (FBG), insulin, glycosylated hemoglobin (HbA1c), homeostasis model assessment of insulin resistance (HOMO‐IR), quantitative insulin sensitivity check index (QUICKI), homeostasis model assessment of β‐cell function (HOMA‐β), triglyceride (TG), total cholesterol (CHOL), high‐density and low‐density lipoprotein cholesterol (HDL‐c and LDL‐c), and atherogenic index of plasma (AIP), inflammatory and oxidative stress markers such as interleukin 6 (IL‐6), total antioxidant capacity (TAC), and malondialdehyde (MDA) and brain‐derived neurotrophic factor (BDNF) were assessed. The results showed a significant decrease in FBG, insulin, HbA1c, HOMO‐IR, LDL‐c, TG, VLDL, CHOL, LDL‐c.HDL‐c ratio, AIP, IL‐6, and MDA and a significant increase in HDL‐c, QUICKI index, BDNF, and TAC compared with the initial value (p for all <.05). In the adjusted model, the mean changes of FBG, insulin, HbA1c, HOMO‐IR, LDL‐c, CHOL, LDL.HDL ratio, AIP, MDA, and IL‐6 were significantly lower and mean changes of QUICKI index, HDL‐c, and TAC were significantly higher in the rutin group compared with the placebo group (adjusted p for all <.05). It seems that rutin may have beneficial effects on improving metabolic parameters, BDNF, and inflammatory and oxidative stress factors in T2DM patients.
Emissions‐Adjusted International Trade for Sustainable Development in China: Evidence from dynamic autoregressive distributed lags model and kernel based regression
Authors: Khan Zeeshan , Badeeb Ramez Abubakr , Hassan Taimoor , Zhang Changyong , Elfaki Khalid Eltayeb 
Published: September 2022

AbstractEfficient allocation of resources and transition towards cleaner sources of energy are among the key factors in minimizing the negative externalities arising from the growing dependency on fossil fuels. Moreover, environmentally benign trade policies are crucial due to the rapid expansion in global trade and comparative advantage. To explore the relationship between global trade and Consumption‐Based Carbon Emissions (CBCE) in China in the context of renewable energy consumption and energy efficiency from 1990 Q1 to 2020 Q4, this paper employs the dynamic Autoregressive Distributed Lags (Dynamic ARDL) model to evaluate the connection between international trade, renewable energy usage, energy efficiency, and CBCE, with the Kernel‐Based Regularized Least Squares analysis being used to determine the causal association. The findings reveal that GDP and imports are directly linked with CBCE in the long run, while exports, energy efficiency, and renewable energy consumption have a negative significant long‐run and short‐run influence on CBCE. In addition, exports help in the reduction of CBCE by sharing and adapting environmentally friendly technologies adopted in, for example, renewable energy and ecological advancements. Renewable energy promotes the quality of the environment, which is attributable to the performance of renewable energy and environmentally friendly technologies that directly stimulate the reduction of CBCE emissions. By cutting CBCE, energy efficiency tends to boost environmental quality. The research findings have noteworthy policy implications; trade enhances the quality of environment by introducing lower energy intensive production methods and technology that support sustainable development. As a result, this study advocated quite stringent policies in terms of aligning international trade orientation with environmental quality policy in China. Furthermore, energy efficiency policies are required to lower CBCE by focusing on high‐energy‐using industries and providing alternative clean energy sources.
Patient Reported Outcome Measures (PROMS) for Body Image in Dermatology: A Systematic Review
Authors: Kristensen Johannes Kjeldstrup , Nielsen Corina , Haloob Nora 
Published: September 2022

Abstract

Introduction
It is widely acknowledged that negative body image perception is linked to anxiety, depression, and body dysmorphic disorder. However, there is no gold standard, body image related patient reported outcome measure in use, specific for dermatologic disease, despite evidence to suggest a high prevalence of mental health problems relating to body image in this group of patients.

Aim
The aim of this study was to perform a review of body image Patient Reported Outcome Measures (PROMs) used in dermatology and to evaluate their effectiveness.

Methods
Searches were performed in the major databases. Two investigators independently performed full text evaluation by applying an established checklist to evaluate the conceptual model, content validity, reliability, construct validity, scoring and interpretability and respondent burden.

Results
Six different PROMs were identified of which only one was fully validated. There was a significant lack of patient involvement in the development of PROMs in this context.

Conclusions
We therefore encourage further research in this field to improve the quality of evidence to better understand the relationship between mental health and dermatologic disease.
Synthesis of Diorganylphosphine Oxides Bearing Hetarylalkyl Moieties and Study of Their Antimicrobial Activities
Authors: Malysheva Svetlana F. , Kuimov Vladimir A. , Belogorlova Natalia A. , Beloveghets Ludmila A. , Albanov Alexander I. , Usoltsev Yurii K. , Trofimov Boris A. 
Published: September 2022

AbstractTertiary phosphine oxides have been synthesized by the reaction of secondary phosphine oxides with diverse hetarylmethylchlorides (pyridines, imidazoles, pyrazole) in the superbasic systems CsF/NaOH/DMF/4 Å MS or NaOH/DMSO/4 Å MS at 23–25 °C. It is found that a tertiary phosphine oxide bearing the imidazole fragment possess the pronounced antimicrobial activity.
Multifunctional Modulation of High‐Performance ZnxFe3−xO4 Nanoparticles by Precisely Tuning the Zinc Doping Content
Authors: Du Hui , Yang Fang , Yao Chenyang , Zhong Zhicheng , Jiang Peiheng , Stanciu Stefan G. , Peng Hao , Hu Jiapeng , Jiang Bo , Li Zihou , Lv Wenhao , Zheng Fang , Stenmark Harald A. , Wu Aiguo 
Published: September 2022

AbstractThe possibility to precisely control important properties of nanoparticles (NPs) such as their size, morphology, surface charge, or doping content is crucial for enhancing the performance of existing solutions beyond the state‐of‐the‐art and for enabling novel applications. In this work, custom‐tailored ZnxFe3−xO4 NPs are synthesized at different Zn doping concentrations to augment and expand their usefulness for high‐performance applications in nanomedicine. By precisely increasing the Zn2+ content in the range of 0 ≤ x ≤ 2.0, the discussed NPs can sequentially acquire valuable properties enabling magnetic resonance imaging, near‐infrared (NIR) photothermal effects, NIR photocatalytic and photoelectric effects, depending on the variation of substitution position of the Zn2+ in the magnetite structure and the emergence of a ZnO/ZnFe2O4 heterostructure at high doping concentrations. The presented work demonstrates and explainsa facile route for the synthesis and modulation of multifunctional nanomaterials with manifold roles in disease diagnostics and therapy, and provides helpful guidance in designing divalent transition metal ion‐doped nanomaterials.
Micro‐Nanocarriers Based Drug Delivery Technology for Blood‐Brain Barrier Crossing and Brain Tumor Targeting Therapy
Authors: Wang Luyao , Shi Youyuan , Jiang Jingzhen , Li Chan , Zhang Hengrui , Zhang Xinhui , Jiang Tao , Wang Liang , Wang Yinyan , Feng Lin 
Published: September 2022

AbstractThe greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB), making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely and effectively penetrate the BBB to achieve targeted drug delivery to brain tumors has been a challenging research problem. With the intensive research in micro‐ and nanotechnology in recent years, nano drug‐targeted delivery technologies have shown great potential to overcome this challenge, such as inorganic nanocarriers, organic polymer‐carriers, liposomes, and biobased carriers, which can be designed in different sizes, shapes, and surface functional groups to enhance their ability to penetrate the BBB and targeted drug delivery for brain tumors. In this review, the composition and overcoming patterns of the BBB are detailed, and then the hot research topics of drug delivery carriers for brain tumors in recent years are summarized, and their mechanisms of action on the BBB and the factors affecting drug delivery are described in detail, and the effectiveness of targeted therapy for brain tumors is evaluated. Finally, the challenges and dilemmas in developing brain tumor drug delivery systems are discussed, which will be promising in the future for targeted drug delivery to brain tumors based on micro‐nanocarriers technology.
Plastic settlement and hardened state assessments of manufactured sand made concrete for varying microfine levels
Authors: Arulmoly Branavan , Konthesingha Chaminda , Nanayakkara Anura 
Published: September 2022

AbstractManufactured sand (MS) has been started utilizing as an alternative in constructions due to the escalated demand for river sand (RS). The microfine aggregate (MFA) is a salient constituent in manufactured sand, which is a crushed reactive form of parent rocks having particles less than 0.075 mm. This paper presents the effects of varying microfine aggregate levels on bleeding, plastic shrinkage cracking (PSC) and compressive strength of MS made concrete. Two types of MS were utilized: MS from Hornblende‐Gneiss rock (MH) and MS from Charnockite rock (MC) and the MFA level was ranged from 0% to 12% at 3% increments and the reference concrete was prepared with RS alone. With the MFA levels, the bleeding of MS concretes was reduced where, at 0% MFA level the maximum bleeding rates were observed for MC (1.63 kg/m2) and MH (0.84 kg/m2) concretes. PSC results were analyzed from an image processing technique, which revealed an increasing trend of mean and maximum crack widths, crack length and crack area with the MFA levels. At 0% MFA, the mean crack width of MC (0.19 mm) and MH (0.17 mm) concretes manifested marginally similar to RS concrete (0.17 mm). The decreasing bleeding with the MFA levels can be attributed to the increasing severity to PSC. Moreover, the optimum 28 days compressive strength of MC (57.5 MPa) and MH (56.1 MPa) concretes was achieved at 3% MFA level which are higher than RS concrete (51.5 MPa). Consequently, the MFA level should be limited to 3% for better plastic and hardened performance of MS made concrete.
Combining debates and reflective activities to develop students' argumentation on socioscientific issues
Authors: Bächtold Manuel , Pallarès Gwen , De Checchi Kévin , Munier Valérie 
Published: September 2022

AbstractThis study aimed to investigate the evolution of students' written argumentation on socioscientific issues (SSIs) during a sequence combining two teaching strategies: debate practice on SSIs and reflective activities on the argumentation produced by students. The quality of their argumentation was assessed considering a set of norms characterizing argumentation practice on SSIs: three generic norms (i.e., justification, others, and questioning norms) and three specific norms (i.e., complexity, uncertainties, and open‐endedness norms). The 2‐year sequence was implemented by teachers from different disciplines in two classes with students aged 16–18. In total, it consisted of four debates on different SSIs and involved four reflective activities following a progression, allowing for the discussion of the generic and specific norms of argumentation on SSIs. The debates were all computer‐mediated and held synchronously in the classroom. They involved students developing their argumentation in a written form. Overall, the results showed positive changes, even if limited, regarding the appropriation of both the generic and specific norms of argumentation on SSIs. The more pronounced changes were observed considering the initial level of the quality of student argumentation in the debates: Students whose initial level was low tended to justify their arguments more frequently, while those with a higher initial level tended to question the claims and arguments more often. Furthermore, at the end of the sequence, students easily coordinated several aspects of the debated SSI, but rarely mentioned knowledge uncertainties and stakeholders of the SSI. These findings imply that combining debates on SSIs with reflective activities is an effective teaching strategy deserving to be disseminated in classroom practices, although two specific norms (i.e., uncertainties and open‐endedness norms) require more in‐depth treatment.
The Accent Work of International Teaching Assistants
Authors: Ramjattan Vijay A. 
Published: September 2022

Abstract“Accent work” is a term used to describe the preparatory work that professional actors undergo to attain a speech accent for a role. However, this article presents international teaching assistants (ITAs) as another set of workers who engage in their own type of accent work. Since the accents of ITAs are constructed as “liabilities” for communication‐based tasks in English‐medium universities in the Global North, their accent work entails ensuring that their speech is not a professional interference. Drawing on a narrative study done with 14 ITAs working in Ontario, Canada, the article details how the accent work of these ITAs consisted of working on or around their accents, which meant modifying accents to various degrees or engaging in tasks that did not require accent modification, respectively. These two practices of accent work were influenced by factors such as academic discipline, social locations, and audience. To conclude, the article offers preliminary recommendations on how accent work can particularly inform ITA training.
Sleep duration and biomarkers of inflammation in African American and white participants with a parental history of Alzheimer's disease
Authors: Pak Victoria M. , Paul Sudeshna , Swieboda Dominika , Balthazar Monique S. , Wharton Whitney 
Published: September 2022

AbstractIntroductionAfrican Americans (AA)s have worse inflammation, worse sleep, and a greater incidence of Alzheimer's disease (AD) compared to whites; however, no studies have examined associations between biomarkers, sleep, and cognition, and differences by race.MethodsSeventy‐six cognitively normal, middle aged (45–65 years) adults with a parental history of AD were included in this study. Associations between biomarkers (tumor necrosis factor‐α [TNF‐α], interleukin‐10 [IL‐10], intercellular adhesion molecule‐1 [ICAM‐1],, and C‐reactive protein [CRP]) and self‐reported sleep or cognition measures, were assessed.ResultsAverage sleep duration was significantly lower for AA versus whites (average[SD]) in hours: 6.02(1.18) versus 7.23(0.91), P = .000004). We found a statistically significant association between plasma IL‐10 and sleep duration (Spearman's ρ = 0.26, P = .04) and CSF ICAM‐1 and sleep quality (Spearman's ρ = 0.30, P = .03).DiscussionLonger sleep duration is positively associated with plasma IL‐10 levels irrespective of race. Sleep quality was positively associated with CSF ICAM‐1 only in African Americans.
Linking emerging contaminants to production and consumption practices
Authors: Johnson Charlotte , Bell Sarah J. 
Published: September 2022

AbstractEmerging contaminants (ECs) associated with consumer products such as pharmaceuticals, personal care products, and plastics, are an issue of growing concern for water quality and human and environmental health. Growth in use of products associated with ECs is an outcome of growing populations, increased incomes and the emergence of new consumer products. Two examples are used illustrate the value of social science research in understanding patterns of consumption and sources of ECs, in order to identify potential interventions to reduce ECs in the environment—flushing inappropriate materials down the toilet, and antibiotic use in global livestock production. Antimicrobial resistance is a major policy driver to control the use of antibiotics in human healthcare and livestock production. Global antibiotic consumption increased 65% 2000–2015. Disposal of products, including unused pharmaceuticals and plastics, is influenced by regulation, consumer behavior, and infrastructure. This range of factors and trends demonstrates the complexity in understanding why ECs enter the aquatic environment and the extent that the issue can be tackled at the source rather than mitigated once in the environment.This article is categorized under:
Engineering Water > Water, Health, and Sanitation
Human Water > Methods
Science of Water > Water Quality