bluuebunny/crossref_metadata_2025_split huggingface dataset:
Finite‐time robust performance improvement for non‐linear systems in the presence of input non‐linearity and external disturbance
Authors: Wang Haoping , Ghaffari Valiollah , Mobayen Saleh , Bartoszewicz Andrzej , Fekih Afef , Assawinchaichote Wudhichai 
Published: November 2022

AbstractThe main focus of this research is on improving the performance of dynamic systems with actuator non‐linearities and time‐varying disturbances. To this end, using the concept of finite‐time stability, a novel observer is presented to estimate the disturbances in systems with input non‐linearities. Then, introducing an innovative sliding manifold, a robust observer‐based technique is derived to guarantee the finite‐time stability of the sliding surface. Hence, the closed‐loop system would be stable in the presence of hard non‐linearities and time‐varying disturbances. The performance of the proposed approach was assessed in using a simulation study of two numerical examples. The obtained results and comparison with a conventional method confirmed the benefits of the suggested approach.
Gate driver power supply arrangement for cascode‐connected super‐junction MOSFETs in a bridge‐leg
Authors: McNeill Neville , Hopkins Andrew , Williams Barry W. 
Published: November 2022

AbstractThis letter presents a circuit for powering cascode gate driver circuits with super‐junction (SJ) MOSFETs in a bridge‐leg. The cascode gate driver gives inherent MOSFET intrinsic diode deactivation, and the bridge‐leg incorporates an inductive turn‐on snubber which controls the charging currents into the MOSFETs’ output capacitances. The cascode driver circuits and snubber inductor are configured such that the gate‐drive energy is derived from the power stage.
A giant umbrella-like stellar stream around the tidal ring galaxy NGC 922
Authors: Martínez-Delgado David , Roca-Fàbrega Santi , Miró-Carretero Juan , Gómez-Flechoso Maria Angeles , Romàn Javier , Donatiello Giuseppe , Schmidt Judy , Lang Dustin , Akhlaghi Mohammad , Hanson Mark 
Published: November 2022

Context. Tidal ring galaxies (TRGs) are rarely observed in the local universe due to their intrinsically transient nature. The tidal ring structures are the result of strong interactions between gas-rich stellar disks and smaller galactic systems, and do not last longer than ∼500 Myr. Therefore, these are perfect scenarios in which to look for the debris of recently accreted dwarf galactic systems.
Aims. Our goal is to study the low surface brightness stellar structures around the TRG NGC 922 and to revise the hypothesis of its formation in light of these new data.
Methods. We present new deep images of the TRG NGC 922 and its surroundings from the DESI Legacy survey data and from our observations with an amateur telescope. These observations are compared with results from high-resolution N-body simulations that were designed to reproduce an alternative formation scenario for this peculiar galaxy.
Results. Our new observations unveil that the low surface brightness stellar tidal structures around NGC 922 are much more complex than reported in previous works. In particular, the formerly detected tidal spike-like structure at the north-east of the central galaxy disk is not connected with the dwarf companion galaxy PGC 3080368, which has been suggested as the intruder triggering the ring formation of NGC 922. The deep images reveal that this tidal structure mainly has a fainter giant umbrella-like shape, and thus it was formed from the tidal disruption of a different satellite. Using the broad-band g, r, and z DESI LS images, we measured the photometric properties of this stellar stream, estimating a total absolute magnitude in the r band of Mr = −17.0 ± 0.03 mag and a total stellar mass for the stream of between 6.9 and 8.5×108 M⊙. We performed a set of N-body simulations to reproduce the observed NGC922-intruder interaction, suggesting a new scenario for the formation of its tidal ring from the infall of a gas-rich satellite around 150 Myr ago. Finally, our deep images also reveal a tidal shell around the dwarf galaxy PGC 3080368, a possible fossil of a recent merger with a smaller satellite, which may suggest it is in its first infall towards NGC 922.
Women's Health Issues in Thrombosis and Haemostasis
Authors: Linnemann Birgit , Hart Christina ,   Speakers of the GTH Working Group "Women's Health"
Published: November 2022

AbstractIn the last couple of years sex specific health issues have continually been gaining attraction by physicians of different medical specialities. Sex differences have been described e.g. in the pathogenesis and mortality in patients affected by COVID-19, in metabolic regulation and cancer mechanisms.1
2
3 In the field of haemostasis, many aspects concerning risk factors, clinical presentation and management of thromboembolic disease and bleeding disorders also display sex differences.
Meat acceptability of crossbred bulls fed a high-grain feedlot diet with antimicrobials and a blend of organic trace minerals and yeast
Authors: Matos Aylle Medeiros , Duarte Vanessa , Tagiariolli Murilo Augusto , Bonin Edinéia , Vital Ana Carolina Pelaes , Guerrero Ana , Prado Rodolpho Martin do , Costa e Silva Luiz Fernando , Ávila Vicente Diaz , Carvalho Venício Macedo , Prado Ivanor Nunes do 
Published: November 2022

Context Natural products, organic trace minerals and yeast have been studied for use as alternatives to antibiotics in improving meat quality and acceptability of bulls finished in feedlots. Aims This study was conducted to evaluate acceptability to consumers of meat from feedlot-finished bulls fed diets containing antimicrobials with or without a natural product based on organic trace minerals and live yeast. Methods Crossbred (European × Nellore) bulls (n = 24, age 24 ± 3 months, weight 385.5 ± 3.8 kg) were fed one of four diets: control, without additives; and three diets that included monensin (ionophore, at 30 mg/kg DM intake) alone or with virginiamycin (antibiotic, at 30 mg/kg DM intake) or with a supplement comprising organic minerals and live Saccharomyces cerevisiae (30 g/100 kg bodyweight). Mineral and microbiological analyses of meat were conducted, and consumer perception of the products, including effects of aging and length of display, was measured. Key results No differences in meat mineral levels were found among treatments (P > 0.05). Consumer acceptability was not modified (P > 0.050) by diet with respect to meat odour, flavour, tenderness and overall acceptability. Meat aged for 7 days had higher scores (P < 0.001) than meat aged for 1 day for all studied attributes except odour (P > 0.05). In the first 7 days of display, meat from bulls fed monensin or monensin + supplement blend had the highest visual acceptability scores (P < 0.001). For all diets, visual acceptability decreased with display time after 5 days (P < 0.001). During the first week of display, consumers showed greatest willingness to buy meat from the treatments with monensin or monensin + supplement blend (P < 0.001). Conclusion A combination of monensin and mineral–yeast blend may be beneficial to meat acceptability and shelf life and promote consumer willingness to buy. Implications Combinations of organic mineral and yeast with conventional additives such as monensin are suitable as supplements to increase meat quality of cattle finished in feedlots and fed high-grain diets.
Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models
Authors: Beumer Joep , Bauzá-Martinez Julia , Veth Tim S. , Geurts Veerle , Boot Charelle , Gilliam-Vigh Hannah , Poulsen Steen S. , Knop Filip K. , Wu Wei , Clevers Hans 
Published: November 2022

Enteroendocrine cells (EECs) secrete hormones in response to ingested nutrients to control physiological processes such as appetite and insulin release. EEC hormones are synthesized as large proproteins that undergo proteolytic processing to generate bioactive peptides. Mutations in EEC-enriched proteases are associated with endocrinopathies. Due to the relative rarity of EECs and a paucity of in vitro models, intestinal prohormone processing remains challenging to assess. Here, human gut organoids in which EECs can efficiently be induced are subjected to CRISPR-Cas9–mediated modification of EEC-expressed endopeptidase and exopeptidase genes. We employ mass spectrometry–based analyses to monitor peptide processing and identify glucagon production in intestinal EECs, stimulated upon bone morphogenic protein (BMP) signaling. We map the substrates and products of major EECs endo- and exopeptidases. Our studies provide a comprehensive description of peptide hormones produced by human EECs and define the roles of specific proteases in their generation.
Possibilising food translation in children’s literature
Authors: Panou Despoina 
Published: November 2022

Abstract
Food is omnipresent in children’s literature, from Popeye’s Spinach to Detective Cluj’s Carpenter Gums, thus signifying its immense cultural value since cultures and societies are built upon food (Keeling and Pollard 2009, 6). Food narratives are capable of performing a number of functions ranging from evoking a sense of coziness and comfort to being a cause of temptation and power struggle, and these functions ought to come under the spotlight when translating children’s books. This article focuses on the English-Greek examination of translation patterns in the Captain Underpants series and on the critical discussion of the translation strategies that have been employed for the transferring of food items to Greek children. To this end, thirty-five examples of food references are analyzed using a purpose-built schema of translation procedures. The results indicate that translators make a conscious attempt to bring foreign dishes closer to the target language culture by adopting a variety of modification and substitution procedures. This study highlights the intrinsic role that the translation tendencies of preservation, modification, substitution, expansion, transcreation, omission, and creation play in enabling food translation, thus bringing to the fore the important yet neglected area of food translation in children’s literature which can have a profound impact not only on literary but also on translational landscapes.
Grammatical variation in World Englishes
Authors: Collins Peter 
Published: November 2022

Abstract
This study adopts an onomasiological, alternation-based approach to the exploration of grammatical variation
across World Englishes, using data sourced from the 1.9 billion-word Global Web-based English corpus. The macro-orientation of the
study, which investigates a set of ten alternations known to be susceptible to diachronic change, facilitates identification of a
number of general trends, including the typical advancement of the Inner Circle varieties and of the South-East Asian varieties,
the hypercentrality of American English, and the epicentrality of Indian English in South Asia. Possible explanatory factors
include colloquialisation, grammatical simplicity/complexity, developmental status, and areal proximity.
Communicating qualitative uncertainty in data visualization
Authors: Panagiotidou Georgia , Vande Moere Andrew 
Published: November 2022

Abstract
Qualitative uncertainty refers to the implicit and underlying issues that are imbued in data, such as the
circumstances of its collection, its storage or even biases and assumptions made by its authors. Although such uncertainty can
jeopardize the validity of the data analysis, it is often overlooked in visualizations, due to it being indirect and
non-quantifiable. In this paper we present two case studies within the digital humanities in which we examined how to integrate
uncertainty in our visualization designs. Using these cases as a starting point we propose four considerations for data
visualization research in relation to indirect, qualitative uncertainty: (1) we suggest that uncertainty in visualization should
be examined within its socio-technological context, (2) we propose the use of interaction design patterns to design for it, (3) we
argue for more attention to be paid to the data generation process in the humanities, and (4) we call for the further development
of participatory activities specifically catered for understanding qualitative uncertainties. While our findings are grounded in
the humanities, we believe that these considerations can be beneficial for other settings where indirect uncertainty plays an
equally prevalent role.
Development of Müller cell-based 3D biomimetic model using bioprinting technology
Authors: Jung Sung Suk , Son Jeonghyun , Yi Soo Jin , Kim Kyungha , Park Han Sang , Kang Hyun-Wook , Kim Hong Kyun 
Published: November 2022

Abstract
Müller cells are the principal glial cells for the maintenance of structural stability and metabolic homeostasis in the human retina. Although various in vitro experiments using two-dimensional (2D) monolayer cell cultures have been performed, the results provided only limited results because of the lack of 3D structural environment and different cellular morphology. We studied a Müller cell-based 3D biomimetic model for use in experiments on the in vivo-like functions of Müller cells within the sensory retina. Isolated primary Müller cells were bioprinted and a 3D-aligned architecture was induced, which aligned Müller cell structure in retinal tissue. The stereographic and functional characteristics of the biomimetic model were investigated and compared to those of the conventional 2D cultured group. The results showed the potential to generate Müller cell-based biomimetic models with characteristic morphological features such as endfeet, soma, and microvilli. Especially, the 3D Müller cell model under hyperglycemic conditions showed similar responses as observed in the in vivo diabetic model with retinal changes, whereas the conventional 2D cultured group showed different cytokine and growth factor secretions. These results show that our study is a first step toward providing advanced tools to investigate the in vivo function of Müller cells and to develop complete 3D models of the vertebrate retina.
Intermediate determinism in general probabilistic theories
Authors: Wright Victoria J 
Published: November 2022

Abstract
Quantum theory is indeterministic, but not completely so. When a system is in a pure state there are properties it possesses with certainty, known as actual properties. The actual properties of a quantum system (in a pure state) fully determine the probability of finding the system to have any other property. We will call this principle, wherein the deterministic elements of a theory completely characterise the probabilistic elements, intermediate determinism. In dimensions of at least three, intermediate determinism in quantum theory is guaranteed by the structure of its lattice of properties. This observation follows from Gleason’s theorem, which is why it fails to hold in dimension two. In this work we extend the idea of intermediate determinism from properties to measurements. Under this extension intermediate determinism follows from the structure of quantum effects for separable Hilbert spaces of any dimension, including dimension two. Then, we find necessary and sufficient conditions for a general probabilistic theory to obey intermediate determinism. We show that, although related, both the no-restriction hypothesis and a Gleason-type theorem are neither necessary nor sufficient for intermediate determinism.
Examining the Impact of Breast Augmentation vs Hormone Therapy on Chest Femininity of Transgender Women
Authors: Zhu Agnes , Callori Steven , Boonipat Thanapoom , Hebel Nathan , Jorge-Martinez Jorys 
Published: November 2022

Abstract

Background
For transgender women, there is often the innate assumption that surgical breast augmentation will increase perceived chest femininity beyond hormone therapy alone.

Objectives
This study aimed to evaluate whether lay individuals found surgically augmented breasts more feminine than breast development from hormone replacement therapy alone in transgender patients.

Methods
We obtained preoperative (maximal breast growth on hormone therapy) and postoperative chest (after primary augmentation) images of 22 transgender patients, and age- and BMI-matched cisgender male (n = 17) and female (n = 21) control patients. Survey respondents (n = 271) rated each image on a scale of 1 (very feminine) to 5 (very masculine). Results were compared by survey respondent gender identity and sexual orientation.

Results
There was a significant difference in mean femininity score between all image types. Mean score for transgender patients fell by 0.478 points after surgery (P &lt; .0001). Subgroup analysis looking at transgender participants revealed the same significance trend postoperatively. Transgender respondents also found no difference in femininity between female controls and postoperative transgender patients (P = .132). We also compared mean femininity scores across 4 self-identified respondent subgroups: cisgender and heterosexual, cisgender and lesbian, gay, or bisexual (LGB), transgender and heterosexual, and transgender and LGB. The cisgender and heterosexual subgroup rated the postoperative transgender patients more feminine than any of the other respondent subgroups (LGB P &lt; .001, transgender and LGB P &lt; .001, transgender only P = .018).

Conclusions
This study shows that breast augmentation significantly increased the perception of femininity. Furthermore, gender identity and sexual orientation are important in how lay persons perceive transgender patients.

Level of Evidence: 4
Intraorbital Fixation Midface Lift
Authors: Bitik Ozan 
Published: November 2022

Abstract

Background
Subperiosteal midface lift provides a comprehensive solution to the soft tissue component of midfacial aging. However, midfacial aging also has a skeletal component that is rarely addressed with conventional mid-facelift techniques. Moreover, many of the adverse outcomes after a mid-facelift are closely related to failures and limitations of mid-face fixation. The author's technique was designed to overcome these limitations.

Objectives
The author aimed to describe the rationale, technical details, and outcomes of the author's mid-facelift technique with intraorbital fixation.

Methods
This study was a retrospective review of 82 nonconsecutive cases where the intraorbital fixation mid-facelift was performed by the author between September 2016 and December 2021. Patient data were obtained from patient records and standardized photography. Preoperative differences in mid-face volume were assessed utilizing the Allergan midface volume deficit scale on standardized photography.

Results
The average mid-face volume deficit score significantly improved after surgery. Failure of fixation, flat midface deformity, and relapse of mid-face ptosis were not seen in any of the primary patients. Infraorbital hollow did not recur in any of the patients operated on with this technique. None of the primary patients (0/58) in this series developed ectropion or permanent lower eyelid malposition.

Conclusions
Intraorbital fixation mid-face lift is an effective and durable surgical option for the treatment of midfacial aging. The technique is applicable in problem cases such as negative vector patients, negative canthal tilt patients, male patients with large bags, and secondary lower blepharoplasties where conventional techniques tend to fail.
beeRapp: an R shiny app for automated high-throughput explorative analysis of multivariate behavioral data
Authors: Busch Anne Marie , Kovlyagina Irina , Lutz Beat , Todorov Hristo , Gerber Susanne 
Published: November 2022

Abstract

Summary
Animal behavioral studies typically generate high-dimensional datasets consisting of multiple correlated outcome measures across distinct or related behavioral domains. Here, we introduce the BEhavioral Explorative analysis R shiny APP (beeRapp) that facilitates explorative and inferential analysis of behavioral data in a high-throughput fashion. By employing an intuitive and user-friendly graphical user interface, beeRapp empowers behavioral scientists without programming and data science expertise to perform clustering, dimensionality reduction, correlational and inferential statistics and produce up to thousands of high-quality output plots visualizing results in a standardized and automated way.

Availability and implementation
The code and data underlying this article are available at https://github.com/anmabu/beeRapp.
An approach of gene regulatory network construction using mixed entropy optimizing context-related likelihood mutual information
Authors: Lei Jimeng , Cai Zongheng , He Xinyi , Zheng Wanting , Liu Jianxiao 
Published: November 2022

AbstractMotivationThe question of how to construct gene regulatory networks has long been a focus of biological research. Mutual information can be used to measure nonlinear relationships, and it has been widely used in the construction of gene regulatory networks. However, this method cannot measure indirect regulatory relationships under the influence of multiple genes, which reduces the accuracy of inferring gene regulatory networks.ApproachThis work proposes a method for constructing gene regulatory networks based on mixed entropy optimizing context-related likelihood mutual information (MEOMI). First, two entropy estimators were combined to calculate the mutual information between genes. Then, distribution optimization was performed using a context-related likelihood algorithm to eliminate some indirect regulatory relationships and obtain the initial gene regulatory network. To obtain the complex interaction between genes and eliminate redundant edges in the network, the initial gene regulatory network was further optimized by calculating the conditional mutual inclusive information (CMI2) between gene pairs under the influence of multiple genes. The network was iteratively updated to reduce the impact of mutual information on the overestimation of the direct regulatory intensity.ResultsThe experimental results show that the MEOMI method performed better than several other kinds of gene network construction methods on DREAM challenge simulated datasets (DREAM3 and DREAM5), three real Escherichia coli datasets (E.coli SOS pathway network, E.coli SOS DNA repair network and E.coli community network) and two human datasets.Availability and implementationSource code and dataset are available at https://github.com/Dalei-Dalei/MEOMI/ and http://122.205.95.139/MEOMI/.Supplementary informationSupplementary data are available at Bioinformatics online.
Accountable Algorithms: Adopting the Public Law Toolbox Outside the Realm of Public Law
Authors: Williams Rebecca 
Published: November 2022

Abstract
It is well known that artificial intelligence, especially machine learning, has the potential for hugely beneficial impacts on all areas of life, but also carries with it dangers such as lack of transparency, over-rigidity of decision-making, negative feedback loops and unreasonable inferences. Such dangers also have the potential to be scaled across a whole area of decisions. There is, therefore, an increasing sense that we need greater accountability of algorithmic decision-making systems and it is argued here that public law and the grounds of judicial review are a ready-made toolkit specifically designed to render decision-makers accountable and to make precisely the kinds of trade-offs we will need to make between effectiveness and efficiency on the one hand and fairness on the other. These tools can therefore provide a blueprint as we work out how to govern ADM and render it accountable, even in a private context. This can take place by using the public law toolkit in interpreting existing legislation, informing future regulation and even through the exercise of a common law supervisory jurisdiction.