bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current Trends in Organ Preservation Solutions for Pancreas Transplantation: A Single-Center Retrospective Study
Authors: Ferrer-Fàbrega Joana , Folch-Puy Emma , Lozano Juan José , Ventura-Aguiar Pedro , Cárdenas Gabriel , Paredes David , García-Criado Ángeles , Bombí Josep Antoni , García-Pérez Rocío , López-Boado Miguel Ángel , Rull Ramón , Esmatjes Enric , Ricart Maria José , Diekmann Fritz , Fondevila Constantino , Fernández-Cruz Laureano , Fuster Josep , García-Valdecasas Juan Carlos 
Published: May 2022

Due to the high vulnerability of the pancreas to ischemia-reperfusion injury, choices regarding preservation solution markedly affect pancreas transplant success. A retrospective single-center analysis of 380 pancreas transplants (2000–2019) was performed to correlate current preservation solutions with transplant outcomes. Early graft failure requiring transplantectomy within 30 days post-transplant occurred in 7.5% for University of Wisconsin (UW) group (n = 267), 10.8% of Celsior (CS) group (n = 83), 28.5% of Histidine-Tryptophan-Ketoglutarate (HTK) group (n = 7), and none for Institut Georges Lopez-1 (IGL-1) group (n = 23). The most common causes of technical failures in this cohort included abdominal hemorrhage (8.4%); graft pancreatitis (3.7%); fluid collections (2.6%); intestinal complications (6.6%); and vascular thrombosis (20.5%). Although IGL-1 solution provided lower surgical complication rates, no significant differences were found between studied groups. Nevertheless, HTK solution was associated with elevated pancreatitis rates. The best graft survival was achieved at 1 year using UW and IGL-1, and at 3 and 5 years using IGL-1 (p = 0.017). There were no significant differences in patient survival after a median follow-up of 118.4 months. In this setting therefore, IGL-1 solution appears promising for perfusion and organ preservation in clinical pancreas transplantation, compared to other commonly used solutions.
Living Donor Liver Transplantation vs. Split Liver Transplantation Using Left Lateral Segment Grafts in Pediatric Recipients: An Analysis of the UNOS Database
Authors: Dalzell Christina , Vargas Paola A. , Soltys Kyle , Dipaola Frank , Mazariegos George , Oberholzer Jose , Goldaracena Nicolas 
Published: May 2022

Split and LDLT in pediatric patients have the potential to decrease wait times and waitlist mortality. Using UNOS-STAR data, we compared outcomes of pediatric patients undergoing LDLT and SLT using LLS grafts. The baseline characteristics and post-operative outcomes were compared between groups. Actuarial graft and patient survival were analyzed with Kaplan-Meier curves. Between 2010 and 2019, 911 pediatric LT were included in the analysis (LD graft group, n = 508, split graft group, n = 403). LD graft recipients spent more time on the waitlist vs. the split graft group (60 (22–138) days vs. 46 (16–108) days; p = 0.007). LD recipients had a lower rate of graft failure, found in 9.8% of patients compared with 14.6% in the split graft group (p = 0.02). HAT was the most common graft failure cause, with similar rates. Graft and patient survival at 1-, 3-, and 5-years was comparable between LDLT and SLT. In subgroup analyses, patients with biliary atresia, those ≤10 kg or ≤10 years old receiving an LD graft showed improved graft survival. In conclusion, LDLT is associated with a lower rate of graft failure in pediatric patients. The use of LLS regardless of the type of donor is a safe way to facilitate access to transplantation to pediatric patients with acceptable short and long-term outcomes.
Clinical risk in remote consultations in general practice: findings from in-COVID-19 pandemic qualitative research
Authors: Rosen Rebecca , Wieringa Sietse , Greenhalgh Trisha , Leone Claudia , Rybczynska-Bunt Sarah , Hughes Gemma , Moore Lucy , Shaw Sara E , Wherton Joseph , Byng Richard 
Published: May 2022

BackgroundThe COVID-19 pandemic-related rise in remote consulting raises questions about the nature and type of risks in remote general practice.AimTo develop an empirically based and theory-informed taxonomy of risks associated with remote consultations.Design & settingQualitative sub-study of data selected from the wider datasets of three large, multi-site, mixed-method studies of remote care in general practice before and during the COVID-19 pandemic in the UK.MethodSemi-structured interviews and focus groups, with a total of 176 clinicians and 43 patients. Data were analysed thematically, taking account of an existing framework of domains of clinical risk.ResultsThe COVID-19 pandemic brought changes to estates (for example, how waiting rooms were used), access pathways, technologies, and interpersonal interactions. Six domains of risk were evident in relation to the following: (1) practice set-up and organisation (including digital inequalities of access, technology failure, and reduced service efficiency); (2) communication and the clinical relationship (including a shift to more transactional consultations); (3) quality of clinical care (including missed diagnoses, safeguarding challenges, over-investigation, and over-treatment); (4) increased burden on the patient (for example, to self-examine and navigate between services); (5) reduced opportunities for screening and managing the social determinants of health; and (6) workforce (including increased clinician stress and fewer opportunities for learning).ConclusionNotwithstanding potential benefits, if remote consultations are to work safely, risks must be actively mitigated by measures that include digital inclusion strategies, enhanced safety-netting, and training and support for staff.
Access to and use of contraceptive care during the first COVID-19 lockdown in the UK: a web-based survey
Authors: Ma Richard , Foley Kimberley , Saxena Sonia 
Published: May 2022

BackgroundThe first wave of lockdown measures to control the COVID-19 pandemic in the UK resulted in suspension of ‘non-essential’ services, including contraceptive care.AimTo examine women’s perceptions and experiences of contraceptive care in the UK during the first lockdown.Design & settingA cross-sectional survey during the lockdown period from March–June 2020.MethodAn online questionnaire was designed asking women aged 16–54 years their experiences of contraceptive care during lockdown. Questions were based on Maxwell’s evaluation framework on access, acceptability, relevance or appropriateness, and equity. It was promoted on social media from 27 May–9 June 2020. A descriptive analysis was conducted of quantitative data and thematic analysis of free-text data.ResultsIn total, 214 responses were analysed. General practice was the source of contraception for 43.4% (n = 49) and 52.3% (n = 34) of responders before and during the lockdown, respectively. The study found 55.1% (n = 118) of responders, including regular and new users, were uncertain where or how to get contraception during the pandemic. Responders reported reduced access to contraception during lockdown, and some thought sexual health clinics and general practices were closed. Remote consultations and electronic prescriptions facilitated contraceptive access for some responders. Long-acting reversible contraception (LARC) was unavailable in some areas owing to restrictions, and alternatives were not acceptable to those who used methods for non-contraceptive benefits to treat medical conditions; for example, menorrhagia.ConclusionThe study highlighted the need for better information and signposting for contraception during lockdown. Contraception, including LARC, should be reframed as an essential service with robust signposting for pandemic planning and beyond.
Physical activity promotion by GPs: a cross-sectional survey in England
Authors: Lowe Anna , Myers Anna , Quirk Helen , Blackshaw Jamie , Palanee Sabrina , Copeland Rob 
Published: May 2022

BackgroundPhysical activity (PA) contributes to the prevention and management of many health conditions. Primary care practitioners have an important role to play in supporting people to be physically active.AimThis study had the following three aims: 1) to explore GPs‘ awareness and knowledge of the PA guidelines; 2) to assess GPs’ confidence in promoting PA; and 3) to explore factors that influence PA promotion among GPs.Design & settingCross-sectional survey, using secondary analysis.MethodUK-based GPs were invited to take part in an online survey in January 2021. Demographic questions were followed by nine multiple choice questions. Categorical data were analysed using descriptive statistics, and open-ended data were analysed using content analysis and inductive coding.ResultsIn total, 839 GPs based in England completed the survey. Most GP responders (98.9%) believed that PA was important, yet only 35.7% reported being at least ‘somewhat familiar’ with current PA guidance. Despite this, 74.1% of GPs reported feeling confident raising the topic of PA with their patients. Barriers included lack of time, perceptions of patient attitude and risk, language issues, and COVID-19. Key facilitators were identified and ‘Couch to 5k’ and the ‘parkrun practice’ initiatives were the most widely used support tools.ConclusionGPs value PA yet well-known barriers exist to embedding promotion into primary care. As primary care reconfigures, there is an opportunity to embed PA into systems, services, and processes.
Perbandingan Metode K-Nearest Neighbor Dan Naïve Bayes Untuk Klasifikasi Gender Berdasarkan Mata
Authors: Kurniawan Calvin , Irsyad Hafiz 
Published: May 2022

Mata merupakan organ penglihatan, yang terletak di rongga orbital. Bentuknya bulat, sekitar 2,5cm. Ruang antara mata dan orbit diisi oleh jaringan gemuk. Dinding tulang dan lemak orbit yang dapat melindungi mata dari terluka.Secara struktural , kedua mata terpisah,tetapi mereka adalah pasangan. Hal Dapat dilihat hanya dengan satu mata, tetapi penglihatan tiga dimensi Merasa tidak nyaman Ketika hanya menggunakan satu mata, terutama dalam hubungan penghakiman jarak. Gender adalah penggolongan secara gramatikal terhadap kata- kata dan kata- kata lain yang berkaitan dengannya yang secara garis besar berhubungan dengan keberadaan dua jenis kelamin atau kenetralan.Penelitian ini bertujuan untuk klasifikasi Gender berdasarkan mata menggunakan metode K-NN dan Naïve Bayes. Data yang dibagi menjadi dua yaitu mata pria dan mata Wanita adalah 10.541 data uji dan 4518 data latih dilanjutkan dengan grayscale, HOG, HSV, Cropping. Pada metode k-NN dengan fitur HSV dan HOG dengan Cropping metode K-NN menghasilkan akurasi yang lebih tinggi di bandingkan Naïve Bayes yaitu sebesar 68,61%.
Pendampingan Dalam Penataan Letak Fasilitas Di UMKM Fuji Rotan Trangsan Gatak Sukoharjo
Authors: Wisudawati Tri , Agusti Febrina , Utomo Widianto Prasetyo , Wicaksono Fajar 
Published: May 2022

Perancangan tata letak fasilitas adalah suatu kegiatan merancang fasilitas fisik yang terdiri dari peralatan, mesin, area, bangunan dan fasilitas lainnya. Fungsi perancangan tata letak fasilitas yaitu memaksimalkan penataan aliran material, aliran informasi dan proses kerja untuk mencapai tujuan yang diinginkan oleh suatu perusahaan. Tujuan utama dari perancangan tata letak fasilitas adalah meminimasi biaya perpindahan bahan dengan waktu yang tersingkat. Kegiatan perancangan fasilitas sering kali digunakan di dunia industri atau pabrik. Perancangan fasilitas pabrik biasanya menganalis, pembentukan konsep, perancangan dan pembuatan suatu sistem tentang produk yang akan dihasilkan atau jasa yang akan diberikan. UMKM Fuji Rotan Trangsan Gatak Sukoharjo dalam layout pabrik / tata letak fasilitas belum begitu tertata sehingga dapat membuat waktu, proses produksi, output dalam produksi kerajinan rotan kurang maksimal sehingga berpengaruh dalam profit usaha. Sehingga, perlu dilakukan penataan layout atau perancangan tata letak fasilitas di UMKM Fuji rotan. Diharapkan dari pengabdian ini UMKM Fuji rotan dapat terbantu dalam perancangan tata letak fasilitas atau penataan layout UMKM. Pelaksanaan kegiatan dari program ini dikemas dalam bentuk beberapa kegiatan yang sifatnya tidak formal, kreatif dan inovatif serta menyenangkan bagi pemilik UMKM Fuji Rotan dan pekerja UMKM Fuji Rotan. Pekerja dan pemilik UMKM akan diberikan pengetahuan mengenai tata letak fasilitas dan bagaimana penerapannya untuk mengoptimalkan sistem produksi yang efektif dan efisien sehingga proses produksi dapat memberikan efek dan profit yang maksimal serta meminimalisir kegiatan yang membuang banyak waktu.
Ekspresi Protein FoxO1 dan Gen Glukosa 6 Fosfatase pada Tikus dengan Diet Restriksi Vitamin B12
Authors: Sianipar Imelda Rosalyn , Andraini Trinovita , Santoso Dewi Irawati Soeria , Ujianti Irena , Antoni Marcel 
Published: May 2022

Pada penelitian awal didapatkan diet restriksi vitamin B12 menyebabkan hiperhomosisteinemia dan resistensi insulin, yang ditandai oleh hiperglikemia dan meningkatnya nilai Homeostatic Model Assessment for Insulin Resistance (HOMA-IR). Dengan menggunakan sampel jaringan biologik tersimpan, hati tikus Spraque-Dawley dari penelitian tersebut, penelitian lanjutan ini bertujuan mengetahui penyebab hiperglikemia, dalam hubungannya dengan proses glukoneogenesis, dengan melihat ekspresi forkhead box protein-O1 (FoxO1) dan gen glukosa 6 fosfatase (G6Pc). Adapun sampel terdiri dari 4 kelompok: kelompok kontrol dan tiga kelompok dengan diet restriksi vitamin B12 masing-masing selama 4, 8, dan 12 minggu. Ekspresi FoxO1 diperiksa dengan metode kuantitatif Western-Blot, sedangkan gen G6Pc diperiksa dengan metode real-time Polymerase Chain Reaction (rt-PCR). Hasil yang diperoleh, tidak terdapat perbedaan bermakna ekspresi FoxO1 (P > 0,05) dan gen G6Pc (P > 0,05) antara kelompok tikus kontrol dan kelompok diet restriksi vitamin B12. Hal ini menunjukkan, hiperglikemia pada diet restriksi vitamin B12 tidak terkait dengan glukoneogenesis. Pada kondisi resistensi insulin, insulin masih dapat meneruskan efek metaboliknya melalui jalur lain, seperti melalui reseptor yang memiliki kemiripan struktur dan fungsi dengan reseptor insu

lin. Penyebab-penyebab lain terjadinya hiperglikemia seperti gangguan utilisasi glukosa oleh sel dan gangguan proses glikogenesis perlu diteliti lebih lanjut.
Self-prioritization with unisensory and multisensory stimuli in a matching task
Authors: Desebrock Clea , Spence Charles , Barutchu Ayla 
Published: May 2022

AbstractA shape-label matching task is commonly used to examine the self-advantage in motor reaction-time responses (the Self-Prioritization Effect; SPE). In the present study, auditory labels were introduced, and, for the first time, responses to unisensory auditory, unisensory visual, and multisensory object-label stimuli were compared across block-type (i.e., trials blocked by sensory modality type, and intermixed trials of unisensory and multisensory stimuli). Auditory stimulus intensity was presented at either 50 dB (Group 1) or 70 dB (Group 2). The participants in Group 2 also completed a multisensory detection task, making simple speeded motor responses to the shape and sound stimuli and their multisensory combinations. In the matching task, the SPE was diminished in intermixed trials, and in responses to the unisensory auditory stimuli as compared with the multisensory (visual shape+auditory label) stimuli. In contrast, the SPE did not differ in responses to the unisensory visual and multisensory (auditory object+visual label) stimuli. The matching task was associated with multisensory ‘costs’ rather than gains, but response times to self- versus stranger-associated stimuli were differentially affected by the type of multisensory stimulus (auditory object+visual label or visual shape+auditory label). The SPE was thus modulated both by block-type and the combination of object and label stimulus modalities. There was no SPE in the detection task. Taken together, these findings suggest that the SPE with unisensory and multisensory stimuli is modulated by both stimulus- and task-related parameters within the matching task. The SPE does not transfer to a significant motor speed gain when the self-associations are not task-relevant.
Universality without uniformity – infants’ reactions to unresponsive partners in urban Germany and rural Ecuador
Authors: Wefers Helen , Schuhmacher Nils , Chacón Ledys Hernández , Kärtner Joscha 
Published: May 2022

AbstractPrevious studies based on non-WEIRD (Western, Educated, Industrialized, Rich, and Democratic) samples provide initial evidence that the still-face effect is universal. Based on the assumption that – independent of their cultural niches – infants share some fundamental expectations of social interactions, we put forth the assumption that a universal response exists for when a social interaction is interrupted. At the same time, we hypothesized that the size of the effect depends on the typicality of the interaction that precedes the adult partners’ interruption. To test these hypotheses, we conducted the Still-Face Paradigm (SFP) with infants (3- and 4.5-month-olds) from two cultural milieus, namely Münster (urban Germany) and the Kichwa ethnic group from the northern Andes region (rural Ecuador), as these contexts presumably offer different ways of construing the self that are associated with different parenting styles, namely distal and proximal parenting. Furthermore, we developed a paradigm that comes much closer to the average expected environment of Kichwa infants, the “No-Touch Paradigm” (NTP). Overall, the results support our initial hypothesis that the still-face effect is universal. Moreover, infants from both cultural milieus responded to the no-touch condition with a change in negative affect. At the same time, some of the infants’ responses were accentuated in a culture-specific way: Kichwa infants had a stronger response to an interruption of proximal interaction patterns during the NTP. While our findings underline infants’ universal predisposition for face-to-face interaction, they also suggest that cultural differences in internalized interactions do influence infant behavior and experience and, in turn, development.
Assessing the Transiting Exoplanet Survey Satellite’s Yield of Rocky Planets Around Nearby M Dwarfs
Authors: Brady Madison T. , Bean Jacob L. 
Published: May 2022

Abstract
Terrestrial planets are easier to detect around M dwarfs than other types of stars, making them promising for next-generation atmospheric characterization studies. The Transiting Exoplanet Survey Satellite (TESS) mission has greatly increased the number of known M-dwarf planets that we can use to perform population studies, allowing us to explore how the rocky planet occurrence rate varies with host radius, following in the footsteps of past work with Kepler data. In this paper, we use simulations to assess TESS’s yield of small (0.5 R
⊕ < R

p
< 2 R
⊕) planet candidates around nearby (d < 30 pc) M dwarfs. We highlight the underappreciated fact that, while TESS was indeed expected to find a large number of planets around M dwarfs overall, it was not expected to have a high planetary yield for the latest M dwarfs. Furthermore, we find that TESS has detected fewer planets around stars with R
⋆ < 0.3 R
⊙ than even was expected (11 observed versus 24 ± 5 expected). We find evidence that the photometric noise of stars in the TESS bandpass increases with decreasing radius for M dwarfs. However, this trend cannot explain the observed distribution of planets. Our main conclusions are (1) the planet occurrence rate likely does not increase, and may decrease for the latest M dwarfs; and (2) there are at least 17, and potentially three times that number, transiting planets around nearby late-M dwarfs that still will not be detected by the end of TESS’s fourth year.
Clumpy Accretion in Pre-main-sequence Stars as a Source of Perturbations in Circumstellar Disks
Authors: Demidova Tatiana V. , Grinin Vladimir P. 
Published: May 2022

Abstract
The development of perturbations in the circumstellar disks of pre-main-sequence stars caused by clumpy accretion was investigated. Here we perform 3D smoothed particle hydrodynamics simulations of disks perturbed by a recent clump accretion event. These simulations are further explored by radiative transfer calculations to quantify the observational appearance of such disks. It was shown that the density waves in the disks were formed at the fall of the clump. After several revolutions they can transform into spirals and ring structures. Their images in millimeter wavelengths are very similar to those observed with Atacama Large Millimeter/submillimeter Array in some protoplanetary disks. We assume that clumpy accretion may be the source of such structures.
NECOLA: Toward a Universal Field-level Cosmological Emulator
Authors: Kaushal Neerav , Villaescusa-Navarro Francisco , Giusarma Elena , Li Yin , Hawry Conner , Reyes Mauricio 
Published: May 2022

Abstract
We train convolutional neural networks to correct the output of fast and approximate N-body simulations at the field level. Our model, Neural Enhanced COLA (NECOLA), takes as input a snapshot generated by the computationally efficient COLA code and corrects the positions of the cold dark matter particles to match the results of full N-body Quijote simulations. We quantify the accuracy of the network using several summary statistics, and find that NECOLA can reproduce the results of the full N-body simulations with subpercent accuracy down to k ≃ 1 hMpc−1. Furthermore, the model that was trained on simulations with a fixed value of the cosmological parameters is also able to correct the output of COLA simulations with different values of Ωm, Ωb, h, n

s
, σ
8, w, and M

ν
with very high accuracy: the power spectrum and the cross-correlation coefficients are within ≃1% down to k = 1 hMpc−1. Our results indicate that the correction to the power spectrum from fast/approximate simulations or field-level perturbation theory is rather universal. Our model represents a first step toward the development of a fast field-level emulator to sample not only primordial mode amplitudes and phases, but also the parameter space defined by the values of the cosmological parameters.
Detecting Baryon Acoustic Oscillations with Third-generation Gravitational Wave Observatories
Authors: Kumar Sumit , Vijaykumar Aditya , Nitz Alexander H. 
Published: May 2022

Abstract
We explore the possibility of detecting baryon acoustic oscillations (BAO) solely from gravitational wave (GW) observations of binary neutron star mergers with third-generation (3G) GW detectors such as the Cosmic Explorer and the Einstein Telescope. These measurements would provide a new independent probe of cosmology. The detection of the BAO peak with current-generation GW detectors (solely from GW observations) is not possible because i) unlike galaxies, the GW mergers are poorly localized, and ii) there are not enough merger events to probe the BAO length scale. With the 3G GW detector network, it is possible to observe

∼

(
1000
)

binary neutron star mergers per year that are localized well within one square degree in the sky for redshift z ≤ 0.3. We show that 3G observatories will enable precision measurements of the BAO feature in the large-scale two-point correlation function; the effect of BAO can be independently detected at different redshifts, with a log-evidence ratio of ∼23, 17, or 3, favoring a model with a BAO peak at redshift of 0.2, 0.25, or 0.3, respectively, using a redshift bin corresponding to a shell of thickness 150h
−1 Mpc.