bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subacute hepatotoxicity of alkaloids extracts of Peganum harmala L. seeds in Wistar albino rats
Authors: BENBOTT Amel , MOSBEH Camellia , KAROUCHE Saida , HAMADOUCHE Nadira , MAHDI Djahida 
Published: July 2022

Peganum harmala L. is a medicinal herbal plant widely used in Algerian traditional medicine. Some reports indicated the toxicity of this plant. In this context, the present study focused on investigate the subacute toxicity of alkaloids extract of P. harmala seeds on histo-function of the liver in rats. Sixteen adult Wistar albino rats were divided equally into four groups, and treated intraperitoneally for 30 days. Group I served as control, received water. Group II, group III, and Group IV received daily a single dose of 50, 100, and 200 mg/kg b.w of crude alkaloids of P. harmala respectively. Blood was collected for the determination of ALT, AST and ALP. Sections of the liver were prepared for histological studies. The results showed a significant decrease in body weights of animals and a significant increase in relative weights of liver in groups III and IV. Treated groups with alkaloids extract of seeds showed a significant increase in the concentration of ALT, AST, and ALP enzymes as compared to control group. These findings were supported with histopathological examination of liver of treated rats. Liver of groups III and IV suffered from severe tissue damage, which included inflammation, cell necrosis, and increase in the volume of some hepatocytes. Some cells contained more than one nucleus and cytoplasm contained micro vacuoles, indicating the onset of steatosis. In conclusion, these biochemical and pathological changes indicate dysfunction with hepatocyte damage. Therefore, the seeds of P. harmala plant must be used in herbal medicine with caution to avoid toxicity to the organism.
A PENGARUH SERVICE QUALITY, RELATIONSHP MARKETING DAN CUSTOMER SATISFACTION TERHADAP REVISIT INTENTION PADA LIA BEAUTY SALON
Authors: I Gusti Made Oka Astana  
Published: July 2022

Abstract. The purpose of this study was to determine how : (1) the effect of service quality on revisit intention (2) the effect of relationship marketing on revisit intention (3) the effect of customer satisfaction on revisit intention. The research was conducted on customer of Lia Beaty Salon. This study uses a quantitative approach. The population in this studi is the customer of Lia Beauty Salon, number of sample is 85 respondens , the sampling technique was non probablity sampling method. . The sample are collected using questionnaires. Data analysis techniqued used in this study is a structural equation model (SEM) based in Partial Least Square ( PLS) with software version 3.3.3.
The result of this study indicate that (1) service quality has a positif and significant effect on revisit intention, (2) relationship marketing has a positif and significant effect on revisit intention, (3) customer satisfaction has a positif and significant effect on revisit intention.

Abstrak. Penelitian ini bertujuan untuk mengetahui: (1) Pengaruh service quality terhadap revisit intention, (2) Pengaruh relationship marketing terhadap revisit intention
(3) Pengaruh customer satisfaction terhadap revisit intention. Penelitian ini dilakukan pada pelanggan Lia Beauty Salon. Penelitian ini menggunakan pendekatan kuantitatif. Populasi dalam penelitian ini adalah pelanggan Lia Beauty Salon. Sampel sebanyak 85 responden yang ditentukan dengan teknik non probability sampling. Pengumpulan data dilakukan dengan cara memberikan daftar pertanyaan dalam bentuk kuesioner kepada responden. Teknik analisis data yang digunakan dalam penelitian ini adalah dengan model persamaan Structural Equation Modeling (SEM) berbasis Partial Last Square (PLS) dengan versi software 3.3.3
Hasil penelitian menunjukkan bahwa (1) service quality berpengaruh positif dan signifikan terhadap revisit intention.
(2) relationship marketing berpengaruh positif dan signifikan terhadap revisit intention. (3) customer satisfaction berpengaruh positif dan signifikan terhadap revisit intention
Promoting student support in Open and Distance learning using Information and Communication Technologies
Authors: Mayanja Jamiah 
Published: July 2022

The study investigated the use of ICTs in students support in Open and Distance learning (ODL) at Makerere University. The study adopted a survey design with 327 ODL students, and the data from participants were collected using self-administered questionnaires and individual interviews. The results showed that, Makerere University has enhanced student support through the introduction of the learning management systems, web-based application, registration and accessing results to ensure student’s satisfaction and retention in ODL system. However limited electronic support is extended to ODL students through e-mails, mobile phones, social media applications, radio and television. The study concludes with recommendations to policy makers at Makerere University. Although, this study has been based in Uganda, the findings may be of relevance to institutions in other developing countries.
Culturally Inclusive Online Learning for Capacity Development Projects in International Contexts
Authors: Gunawardena Charlotte Nirmalani 
Published: July 2022

This paper explores cultural inclusivity in online learning design by discussing two international capacity development projects; an online tutor mentor development program in Sri Lanka and a hybrid physician assistant training program in Ghana. Inclusivity involves establishing partnerships and conducting needs assessments to maximize the capacity that already exists within a given context, and addressing cultural factors that impact online learning: developing a learning community, negotiating identity, power, and authority, generating social presence, supporting collaboration, engaging in authentic inquiry-based learning, navigating interactions in a second language, and developing co-mentoring relationships to support learning. The paper provides a framework, WisCom (Wisdom Communities) to guide the design of culturally inclusive online learning incorporating lessons learned from international projects. By emphasising divergent thinking, consensus building, and the exploration of multiple solutions to complex, real-world problems, WisCom maximizes opportunities for participants’ diverse backgrounds and experiences to be valued.
Fostering Rapid Institution-wide Curricular Change in Response to COVID-19
Authors: Werth Eric , Williams Katherine , Werth Lori 
Published: July 2022

To aid students during COVID-19, the University of Pikeville transitioned all undergraduate classes to no-cost alternatives for course textbooks. Additionally, the academic calendar was modified for the first time in the institution’s 130-year history from a traditional 16-week semester to 8-week block scheduling. This case study explores strategies, approaches to corresponding with constituents, and lessons learned in leading an institution through two major curricular changes in under six months in response to a global pandemic.
Geothermal System in Parang Wedang, Yogyakarta, Indonesia
Authors: Iqbal Mochamad , Juliarka Bella Restu 
Published: July 2022

Geothermal manifestations in Parangtritis, Indonesia, known as Parang Wedang Hot Spring, indicate a geothermal system in the subsurface. This circumstance motivated our research to model the Parang Wedang geothermal system in order to determine its subsurface conditions. Geological mapping, the geophysical method, and geochemical analysis were integrated to produce a conceptual model of the Parang Wedang geothermal system. The study area consists of structural hills, karst hills, and eolian plains with andesite breccias, limestone, andesite, and sand deposits as lithological variations. The results of magnetic modeling indicate that the research area is associated with the presence of an andesite intrusion and shows a NE-SW trending geological structure that is thought to be a path for hydrothermal fluid to the surface. Geochemical analysis was performed at two hot springs with temperatures of 47 °C and 49 °C. Geothermometer calculation showed that the geothermal reservoir in Parang Wedang has a temperature of 100 to 120 °C, a depth of about 180 to 285 m, and can be classified as a low enthalpy geothermal system.
FAKTOR-FAKTOR YANG MEMENGARUHI KEPUTUSAN MENGINAP DI HOiTEL SANTIKA PADA MASA PANDEMI
Authors: Sofiani Sofiani , Natalia Dessy , Paulina Paulina 
Published: July 2022

Pandemi Covid-19 telah menyebabkan berbagai dampak, terutama bagi sektor pariwisata dan industri perhotelan. Santika Indonesia Hotels & Resorts menutup sebagian besar unit hotelnya akibat Pandemi Covid-19. Agar bisnisnya dapat tetap berjalan, hotel harus menyesuaikan operasionalnya dengan menerapkan berbagai protokol kesehatan. Era normal baru ini menimbulkan adanya perubahan perilaku masyarakat, termasuk dalam hal berwisata. Penting bagi pihak manajemen hotel untuk mempelajari perilaku calon tamunya yang dapat mempengaruhi keputusan menginapnya. Melalui penelitian ini, diharapkan dapat membantu mengetahui faktor pengaruh keputusan menginap di Hotel Santika pada masa pandemi. Teori yang digunakan adalah Theory of Planned Behaviour (Ajzen, 1991) terdapat tiga jenis pertimbangan yang mempengaruhi perilaku manusia, yaitu siikap, norima subjektif dan kontroil periilaku yang dipersepisikan. Berdasarkan hasil uji t, diketahui bahwa ketiga faktor tersebut berpengaruh secara signifikan terhadap keputusan menginap tamu. Berdasarkan hasil uji F, diketahui bahwa secara simultan, ketiganya berpengaruh secara signifikian terhadap keputusan menginap. Berdasarkan hasil uji koefisien determinasi, diketahui bahwa sumbangan pengaruh terhadap keputusan menginap dari ketiga faktor tersebut yaitu sebesar 73%. Manajemen Hotel Santika diharapkan dapat lebih meningkatkan sosialisasi terkait penerapan Protokol Kesehatan, membuat program-program tertentu yang dapat menciptakan pengalaman positif, menjaga agar ulasan hotel tetap positif, dan membuat berbagai tawaran menarik yang disesuaikan dengan kemampuan target pasar.
Genetic Variability and Correlation Study in Determinate Type Progenies of Indian Bean [Lablab purpureus (L.) Sweet]
Authors: Patel G. M. , Kale B. H. , Kyada A. D. , Modha K. G. , Chauhan D. A. , Patel R. K. 
Published: July 2022

Aims: In India, the Indian bean is a popular vegetable and legume crop. An attempt was made to analyze the variability, correlation as well as direct-indirect effects using path analysis for yield and its sub-characters.
Place and Duration of Study: Navsari Agricultural University, Navsari, Gujarat. In Rabi 2019-20.
Methodology: The investigation was conducted using 55 genotypes in a randomized block design using three replications. Total of eleven quantitative traits were studied and data was collected from ten random plants from each genotype.
Results: ANOVA depicted sufficient variability present among the genotypes for all traits. Plant height, racemes per plant, pods per raceme, pod weight, pods per plant, pod width, and seed yield per plant showed moderate to high GCV (Genotypic coefficient of variation) and PCV (Phenotypic coefficient of variation), moderate to high heritability, and moderate to high genetic advance as a per cent of mean. Plant height, racemes per plant, pods per plant, pod weight, and pods per raceme were significantly and positively associated with seed yield per plant at the genotypic level. Pods per plant had the most favorable direct effects (0.736) on seed yield per plant, subsequently by pod weight, seeds per pod, pods per raceme, pod length, pod width, plant height and days to maturity.
Conclusion: It is concluded that sufficient amount of variability is present within the material under study. The selection for pods per plant, pods per raceme, pod weight, pod length, pod width, plant height, seeds per pod and days to maturity would be easy and useful in bringing about improvement of seed yield in Indian bean.
mRNA Vaccines Against SARS‐CoV‐2 Variants Delivered by Lipid Nanoparticles Based on Novel Ionizable Lipids
Authors: Chen Kepan , Fan Na , Huang Hai , Jiang Xin , Qin Shugang , Xiao Wen , Zheng Qian , Zhang Yupei , Duan Xing , Qin Zeyi , Liu Yongmei , Zeng Jun , Wei Yuquan , Song Xiangrong 
Published: July 2022

AbstractSARS‐CoV‐2 variants are now still challenging all the approved vaccines, including mRNA vaccines. There is an urgent need to develop new generation mRNA vaccines with more powerful efficacy and better safety against SARS‐CoV‐2 variants. In this study, a new set of ionizable lipids named 4N4T are constructed and applied to form novel lipid nanoparticles called 4N4T‐LNPs. Leading 4N4T‐LNPs exhibit much higher mRNA translation efficiency than the approved SM‐102‐LNPs. To test the effectiveness of the novel delivery system, the DS mRNA encoding the full‐length S protein of the SARS‐CoV‐2 variant is synthesized and loaded in 4N4T‐LNPs. The obtained 4N4T‐DS mRNA vaccines successfully trigger robust and durable humoral immune responses against SARS‐CoV‐2 and its variants including Delta and Omicron. Importantly, the novel vaccines have higher RBD‐specific IgG titers and neutralizing antibody titers than SM‐102‐based DS mRNA vaccine. Besides, for the first time, the types of mRNA vaccine‐induced neutralizing antibodies are found to be influenced by the chemical structure of ionizable lipids. 4N4T‐DS mRNA vaccines also induce strong Th1‐skewed T cell responses and have good safety. This work provides a novel vehicle for mRNA delivery that is more effective than the approved LNPs and shows its application in vaccines against SARS‐CoV‐2 variants.
Enabling Transparent‐Conductive‐Oxide Free Efficient Heterojunction Solar Cells by Flexibly Using Dopant‐Free Contact
Authors: He Jian , Wang Genshun , Qiu Yibin , Tang Zeguo , Ye Fan , Zhang Chaohua , Wang Shulin , Cai Lun , Yu Tianbao , Gao Pingqi 
Published: July 2022

AbstractMinimizing the optical parasitic absorption loss in hydrogenated amorphous silicon (a‐Si:H) and transparent conductive oxide (TCO) layers is considered an effective approach to further improve the power conversion efficiencies (PCEs) of crystalline silicon heterojunction (SHJ) solar cells. In this work, carrier‐selective passivating contacts for both polarities, e.g., alkali fluoride/aluminum electron‐selective contact and transition metal oxide/silver hole‐selective contact, are used to completely replace the doped a‐Si:H layers in SHJ solar cell, forming a totally TCO‐ and dopant‐free asymmetric structure. By minimizing the charge carrier transporting and recombination losses on the front‐side electron‐selective contact through interface engineering, an improved photovoltaic performance with a short‐circuit current density of 40.5 mA cm−2, an open‐circuit voltage of 0.709 V, and a fill factor of 79.6% is realized, resulting in a final PCE exceeding 22.9%. The successful demonstration of this work provides an effective way to further boost the efficiency, as well as reduce the cost of SHJ solar cells with a TCO‐free and doped a‐Si:H‐free configuration, using a moderate and simplified fabrication process.
Soft Optoelectronic Sensors with Deep Learning for Gesture Recognition
Authors: Zhao Lei , Wu Bei , Niu Yao , Zhu Shengke , Chen Ye , Chen Huanyang , Chen Jin‐hui 
Published: July 2022

AbstractWith the rapid development of deep learning and computing power, human–computer interactions, and interfaces are attracting attentions in industrial and academic research. Flexible human–computer interaction can greatly improve productivity and enable robots to work in extreme environments that humans cannot tolerate. The research of gesture recognition is emerging and provides a new way of studying the human–computer interactions. However, compared with the entire human body, human hands are dexterous organs with more complex and flexible joints, which makes hand gesture recognition a challenging problem. Here, a robust and cost‐effective gesture recognition system is reported through the soft optoelectronic sensors. An array of polymer‐encapsulated U‐shaped microfiber (UMF) attached to a glove is fabricated for sensitive finger motion detection. The anisotropic strain response of UMF is measured with a sensitivity of 15.98 (2.20) in the x‐direction (y‐direction). A deep learning network (VGGNet) is developed to process the optical signals for analyzing and classifying hand gestures. The experiments show that VGGNet has high recognition accuracy of 99.2% for the test datasets with ten classified gestures. This work provides a potential optical interface in studying gesture recognition and biomechanical signatures, which can also be applied in virtual reality systems and interactive game platforms.
Inorganic‐Nanoparticle‐Based Super‐Hydrophobic Colored Coatings for Sustainable Building‐Integrated Photovoltaics
Authors: Yeo Seon Ju , Bera Sandipan , Kim Buseong , Kim Dong‐Gyu , Lee Bo‐Yeon , Park Seung‐Chul , Lim Hyuneui 
Published: July 2022

AbstractBuilding‐integrated photovoltaics (BIPVs) have gained significant attention by promising renewable electricity without concerns of additional space, environmental damage, and maintenance problems. However, silicon‐based BIPVs generally limit aesthetic appearance due to their monotonous dark blue modules. In addition, maintaining performance is challenging because BIPV modules are easily contaminated by particulate matter, hindering practical applicability. In this study, a solution‐based process of functional nanoparticles (NPs) is employed to fabricate large‐area colored films with self‐cleaning properties. The stable and robust NPs comprising inorganic‐based fluorinated silica (F‐SiO2) NPs and silica‐coated gold (Au@SiO2) NPs are synthesized for self‐cleaning and aesthetic integration, respectively. The NPs are then self‐assembled into a hierarchical structure with the aid of a silicone‐based binder over a large area (1 m2) using customized convective‐assembly equipment, resulting in tunable colored hydrophobic and super‐hydrophobic surfaces. Finally, they are applied on the front glass of BIPV modules of a 3 kW solar system on a constant over 1 year, with a system energy efficiency of ≈89.5%. Moreover, the colored glass modules show excellent stability after damp heat (85 °C/85%) and accelerated weathering tests. Hence, they are expected to be utilized as a functional colored film for sustainable BIPVs.
Short‐Wave Infrared Chip‐Spectrometer by Using Laser Direct‐Writing Grayscale Lithography
Authors: Xuan Zhiyi , Wang Zi , Liu Qingquan , Huang Songlei , Yang Bo , Yang Liyi , Yin Zhiqin , Xie Maobin , Li Chenlu , Yu Jingyi , Wang Shaowei , Lu Wei 
Published: July 2022

AbstractShort‐wave infrared (SWIR) information is critical for material analysis, imaging sensing, and other fields. To acquire SWIR spectrum with compact devices, strategies for reconstructive microspectrometer have emerged, such as photonic crystal and quantum dot filter. However, the current SWIR microspectrometer needs many filters with insufficient resolution. In this work, the authors develop a SWIR chip‐spectrometer based on Fabry–Perot microcavities array which can be fabricated by using fast and low‐cost UV laser direct‐writing grayscale lithography. The ultra‐compact chip‐spectrometer can work in a very wide range from 900 to 1700 nm with only 20 detector pixels and a reconstruction algorithm. The spectral resolution achieves 2 nm by 50 pixels set and 5 nm by 20 pixels set at SWIR range, which is 3 times higher, with 3.9 times less units number, than for recently reported SWIR quantum dot spectrometers. To the best of our knowledge, this is a minimum high‐resolution SWIR InGaAs detector based chip‐spectrometer which can work in the whole SWIR band with only 20 detector pixels. It has great potential for applications in smart‐phone or other miniature portable spectrometers.
Engineering Intramolecular π‐Stacking Interactions of Through‐Space Charge‐Transfer TADF Emitters for Highly Efficient OLEDs with Improved Color Purity
Authors: Wang Junjie , Miao Jingsheng , Jiang Chenglin , Luo Sai , Yang Chuluo , Li Kai 
Published: July 2022

AbstractPurely organic compounds with thermally activated delayed fluorescence (TADF) are promising sustainable emitters for organic light‐emitting diodes. But the simultaneous realization of a high efficiency, short lifetime, and good color purity in single TADF molecule remains challenging. Herein it is reported that the confinement of rigid and planar N‐ and B‐centered donor and acceptor in sandwich‐type structures, named BNB‐m and BNB‐p, can lead to green TADF emissions with up to unity efficiency and improved color purity from through‐space charge‐transfer excited states. The full width at half maximum of 58 nm (0.28 eV) for BNB‐m is significantly smaller than those for most of the TADF emitters having a twisted donor‐acceptor structure. Single‐crystal structures, NMR spectroscopy, and theoretical simulations manifest the presence of strong noncovalent π‐stacking interactions in BNB‐m which account for the reduced intramolecular motions and enhanced through‐space electronic coupling. With a relatively short delayed fluorescence lifetime of 11 µs, the emitter BNB‐m demonstrates attractive green electroluminescence with a maximum external quantum efficiency (EQE) of 34.9% and an EQE of 27.4% at 1000 cd m−2. This work validates a promising molecular design to TADF emitters which can realize a balanced emission property in terms of color purity and emission lifetime.
Rational Amphiphilic Ligand Engineering Enables Enhanced Stability and Efficiency of CsPbBr3 Nanocrystals Based Light Emitting Diodes
Authors: Duan Yanyan , Chordiya Kalyani , Kahaly Mousumi Upadhyay , Oropeza Freddy E. , de la Peña O'Shea Víctor A. , Wang De‐Yi , Costa Rubén D. 
Published: July 2022

AbstractMetal halide perovskites have shown great potential for lighting. However, their low stability under irradiation/thermal stress and/or ambient storage conditions are critical for light‐emitting diodes (LEDs). Among the stabilization strategies, ligand surface modification is effective toward stable perovskites, but the dynamic ligand adsorption/desorption process on the surface is a limiting factor. Herein, a new family of biogenic and amphiphilic capping agents, phosphatidyl‐L‐serine (Ptd‐L‐Ser), combining stronger multibinding motifs compared to conventional capping agents has led to superior CsPbBr3 (CsPbBr3‐Ptd‐L‐Ser) with significantly enhanced stability upon storage/heating/water, keeping excellent photoluminescence quantum yields of ≈80% over half year. Spectroscopic/theoretical studies reveal that the origin of this behavior is the increased exciton binding energy associated to the versatility of multiple bindings. This results in CsPbBr3‐Ptd‐L‐Ser nanocrystals‐based green‐LEDs featuring excellent stabilities of >700 h (20 mA) and >200 h (100 mA) that strongly contrast with the reference devices with pristine CsPbBr3 nanocrystals (120 h (20 mA) and 27 h (100 mA)). White LEDs (WLEDs) with chromaticity coordinates of (0.34, 0.33) and high luminous efficiency of 76 lm W–1, keeping stable over weeks, are further demonstrated under continuous operational conditions, thereby suggesting CsPbBr3‐Ptd‐L‐Ser nanocrystals can be a potential candidate for commercial WLED technology.