bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Mean Kinematic Structure of the Tropical Cyclone Boundary Layer and Its Relationship to Intensity Change
Authors: Zhang Jun A. , Rogers Robert F. , Reasor Paul D. , Gamache John 
Published: September 2022

Abstract
This study investigates the relationship between the azimuthally averaged kinematic structure of the tropical cyclone boundary layer (TCBL) and storm intensity, intensity change, and vortex structure above the BL. These relationships are explored using composites of airborne Doppler radar vertical profiles, which have a higher vertical resolution than typically used three-dimensional analyses and, therefore, better capture TCBL structure. Results show that the BL height, defined by the depth of the inflow layer, is greater in weak storms than in strong storms. The inflow layer outside the radius of maximum tangential wind speed (RMW) is deeper in intensifying storms than in nonintensifying storms at an early stage. The peak BL convergence inside the RMW is larger in intensifying storms than in nonintensifying storms. Updrafts originating from the TCBL are concentrated near the RMW for intensifying TCs, while updrafts span a large radial range outside the RMW for nonintensifying TCs. In terms of vortex structure above the BL, storms with a quickly decaying radial profile of tangential wind outside the RMW (“narrow” vortices) tend to have a deeper inflow layer outside the RMW, stronger inflow near the RMW, deeper and more concentrated strong updrafts close to the RMW, and weaker inflow in the outer core region than those with a slowly decaying tangential wind profile (“broad” vortices). The narrow TCs also tend to intensify faster than broad TCs, suggesting that a key relationship exists among vortex shape, the BL kinematic structure, and TC intensity change. This relationship is further explored by comparisons of absolute angular momentum budget terms for each vortex shape.
Risk factors for suicidal behavior: A Romanian mixed methods study
Authors: Vuscan Mihaela Elvira , Faludi Cristina , Buciuta Andrei , Vica Mihaela Laura , Balici Stefana , Siserman Costel Vasile , Coman Horia George , Matei Horea Vladi 
Published: September 2022

Objectives: This study had two purposes: to explore the main socio-demographic and medical characteristics of the psychiatric patients with a history of suicidal behavior, and to identify the main risk factors underlying the suicidal ideation and acts among psychiatric patients, in the light of two recent theories of suicidal behavior. Methods: The study is based on a mixed methodological design. During 2019 to 2021, 65 hospitalized psychiatric patients, who committed at least one non-lethal suicide attempt, were investigated using a questionnaire a scales for data collection. Medical records were used to gather data about certain socio-demographic characteristics and the health status of the respondents. Patients also participated in a narrative interview aimed at disclosing their subjective experiences about their past suicidal behavior. Results: The typical psychiatric patient with a history of suicidal behavior, as highlighted by the quantitative analysis, portraits a young old male from an urban environment, childless, educated, having experienced employment problems, being involved in religious activities. The clinical picture of the patient with suicidal antecedents included a moderate or severe level of depression, the presence of socio-emotional loneliness, the manifestation of frequent and long episodes of suicidal ideation, and the intention of committing suicide in order to stop the pain, whose acts resulted in minor injuries. Findings from the qualitative data revealed four major risk factors for the non-lethal suicidal attempts: family disruptions and social problems; economic burdens; a mixture of psychiatric pathologies; and, to a lesser extent, somatic pathologies. Conclusion: This study is the first to explore the triggers of suicide acts conducted in a clinical environment in the Balkan region. Implications of the pandemic are also discussed. The findings are useful for designing prevention strategies based on individual psychotherapy and therapeutic or support groups, addressing the main risk factors behind the suicidal ideation and gestures.
Cutoff for Benchmark Disability Using World Health Organization Disability Assessment Schedule 2.0: A Community-Based Cross-Sectional Study from Rural South India
Authors: Ravindran Swati , Jadhav Prabhu , Philip Sharad , Basavarajappa Chethan , Kumar Channaveerachari Naveen , Thirthalli Jagadisha , Sivakumar Thanapal 
Published: September 2022

Background: India uses the Indian Disability Evaluation and Assessment Scale (IDEAS) for quantifying disability due to mental illness. The cutoff score for benchmark disability is 7. India has adopted International Classification of Functioning and Health (ICF) and thereby is a signatory to use World Health Organization Disability Assessment Schedule (WHODAS). Cutoff for benchmark disability in WHODAS in a community-based sample is lacking. Methods: The study was conducted in Jagaluru Taluk, Davanagere District, Karnataka. It is a part of an ongoing research funded by Indian Council of Medical Research. Frequency, percentages, mean, standard deviations, mode, median, Receiver Operating Characteristic Curve were used in analyzing the data. Results: The study included 184 persons with severe mental illness with mean age of 47 and average duration of illness (DOI) of 11 years. They had mild disability (5.99) in IDEAS. The corresponding cutoff score in WHODAS, as compared to IDEAS, when the influence of DOI is removed was 24. Conclusions: A shift from IDEAS to WHODAS is feasible. With the undue influence of DOI removed, both hospital and community-based samples show the score of 24 as cutoff.
‘You can’t feel what we feel’: Multifaceted dyspnoea invisibility in advanced chronic obstructive pulmonary disease examined through interpretative phenomenological analysis
Authors: Serresse Laure , Guerder Antoine , Dedonder Jonathan , Nion Nathalie , Lavault Sophie , Morélot-Panzini Capucine , Gonzalez-Bermejo Jésus , Benoit Laelia , Similowski Thomas 
Published: September 2022

Background: More than a symptom, dyspnoea is an existential experience shaping the lives of those afflicted, particularly when its persistence despite maximal pathophysiological treatments makes it pervasive. It is, however, insufficiently appreciated by concerned people themselves, family members, healthcare professionals and the public (dyspnoea invisibility), limiting access to appropriate care and support. Aim: To provide a better understanding of dyspnoea experiences and its invisibility. Design: Interpretative phenomenological analysis of data collected prospectively through in-depth semi-structured interviews. Setting/Participants: Pulmonary rehabilitation facility of a tertiary care university hospital; 11 people (six men, five women) with severe chronic obstructive pulmonary disease (stages 3 and 4 of the 4-stage international GOLD classification) admitted for immediate post-exacerbation rehabilitation. Results: We identified several types of dyspnoea invisibility depending on temporality and interlocutors: (1) invisibility as a symptom to oneself; (2) invisibility as a symptom to others; (3) invisibility as an experience that cannot be shared; (4) invisibility as an experience detached from objective measurements; (5) invisibility as an experience that does not generate empathic concern. The notion of invisibility was present in all the identified experiential dimensions of dyspnoea. It was seen as worsening the burden of the disease and as self-aggravating through self-isolation and self-censorship. Conclusions: The study confirmed that dyspnoea invisibility is a reality for people with advanced chronic obstructive pulmonary disease. It shows dyspnoea invisibility to be a multifaceted burden. Future research should aim at identifying individual and collective measures to overcome dyspnoea invisibility.
Evaluating Medication Day-Supply for Improving Adherence and Clinical Biomarkers of Hemoglobin A1c, Blood Pressure, and Low-Density Lipoprotein
Authors: Ameli Nina , Jones William N. 
Published: September 2022

Objectives: To compare a 90-day-supply and a less than 90-day-supply of medication on adherence to refilling prescriptions and clinical biomarkers for hemoglobin A1c (HbA1c), blood pressure (BP), and low-density lipoprotein (LDL). Methods: A retrospective chart review was completed for a cohort of patients prescribed an oral hypoglycemic agent (OHA), angiotensin-converting enzyme inhibitor (ACEI), or angiotensin II receptor blocker (ARB), and/or a statin. Data were categorized into 90-day-supply and less than 90-day-supply and on the minimum value for control determined by the CMS Star Ratings system. Adherence was defined by the Health Plan Quality Improvement Department as ≥ 85% of days covered. Clinical biomarker cutoffs were HbA1c (<9% or ≥ 9%), BP (Systolic BP ≤ 140 mm Hg and >140 mm Hg or Diastolic BP ≥ 90 mm Hg regardless of SBP), and LDL (<100 mg/dl or ≥100 mg/dl). Results: The analysis included 251 patients: 159 females (mean 64.9 ± 11.7 years) and 92 males (mean 61.5 ± 11.3 years). Patients with medications from multiple classes were included in more than one analysis. Adherence was statistically in favor of the 90-day-supply compared to less than 90-day-supply for all three classes of drugs. The clinical biomarkers were statistically not different for each drug group. Conclusion: A 90-day-supply was statistically greater than a less than 90-day-supply for CMS Star Ratings metrics, but was not statistically significant for clinical biomarkers for HbA1c, SBP, and LDL.
Survey on Mite Infestations in Small Ruminants in Kindo Didaye District, Wolaita zone, Southern Ethiopia
Authors: Fesseha Haben , Gamo Getero , Mathewos Mesfin , Mekonnen Endale 
Published: September 2022

Background: Mange is a parasitic skin disease caused by microscopic mites that feed on the skin of small ruminants and affect animal productivity. Methods: A study was carried out to determine the prevalence and possible risk factors for mite infestation in small ruminants in Kindo Didaye district, Wolaita zone, southern Ethiopia. Skin scraping samples were collected from 384 small ruminants (196 goats and 188 sheep) for the identification of mite species following the standard parasitological protocol. Results: Of the 384 examined animals, 6.25% of sheep and goats were infested with different mite species, namely, Sarcoptes (3.67%), Demodex (1.54%), and mixed infestation of Sarcoptes and Demodex (1.04%). A relatively higher prevalence of mite infestation occurred in goats (7.14%) than in sheep (5.3%), and the highest prevalence of lesions of mange mites was recorded in the neck region (3.13%). The multivariate analysis of factors revealed that only BCS and herd size have a significant role in mite infestation of small ruminants. In addition, the correlation analysis of mite infestation with factors revealed that herd size ( r = .106), sex (.0434), and body condition score ( r = .104) had a positive correlation with mite infestation. Conclusion: Mites are among the most important health constraints of sheep and goats in the study area, requiring immediate attention and control interventions. Moreover, further epidemiological investigations that consider agroecology and other nonhost-related risk factors should be carried out for the appropriate control of mange mites.
Effects of Moderate-Intensity Training Under Cyclic Hypoxia on Cardiorespiratory Fitness and Hematological Parameters in People Recovered From COVID-19: The AEROBICOVID Study
Authors: Dellavechia de Carvalho Carlos , Bertucci Danilo Rodrigues , Ribeiro Felipe Alves , Costa Gabriel Peinado , Toro Diana Mota , Camacho-Cardenosa Marta , Brazo-Sayavera Javier , Sorgi Carlos Arterio , Papoti Marcelo , Trapé Átila Alexandre 
Published: September 2022

Background: Recent studies have indicated that people who live at altitude have a lower incidence of coronavirus disease (COVID-19) and lesser severity in infection cases. Hypothesis: Hypoxia exposure could lead to health benefits, and it could be used in the recovery process as an additional stimulus to physical training to improve cardiorespiratory fitness (CRF). Study Design: Randomized controlled clinical trial. Level of Evidence: Level 2. Methods: The 43 participants, aged 30 to 69 years, were divided into control group (CG, n = 18) and 2 training groups: normoxia (NG, n = 9) and hypoxia (HG, n = 16). Before and after the intervention were evaluated the lactate threshold 2 (L2), peak oxygen uptake (VO2peak), and a blood sample was collected at rest to evaluate hematological adaptation. Both groups performed an 8-week moderate-intensity physical training on a bike. The HG were trained under normobaric hypoxic conditions (fractional inspired oxygen [FiO2] = 13.5%). Results: The 8-week intervention promoted a similar improvement in CRF of people recovered from COVID-19 in the HG (L2 = 34.6%; VO2peak = 16.3%; VO2peak intensity = 24.6%) and NG (L2 = 42.6%; VO2peak = 16.7%; VO2peak intensity = 36.9%). Only the HG presented differences in hematological variables (erythropoietin = 191.7%; reticulocytes = -32.4%; off-score = 28.2%) in comparison with the baseline. Conclusion: The results of the present study provide evidence that moderate-intensity training in normoxia or hypoxia promoted similar benefits in CRF of people recovered from COVID-19. Furthermore, the hypoxia offered an additional stimulus to training promoting erythropoietin increase and hematological stimulation. Clinical Relevance: The present exercise protocol can be used for the rehabilitation of people recovered from COVID-19, with persistent low CRF. In addition, this is the first study demonstrating that physical training combined with hypoxia, as well as improving CRF, promotes greater hematological stimulation in people recovered from COVID-19.
Sexual violence and adverse reproductive health outcomes among youth females in North Shoa zone, Oromia, Ethiopia: A community-based cross-sectional study
Authors: Mekonnen Mathewos , Jemal Kemal , Tilahun Ayele , Getaye Asfaw , Bekele Kumera , Hailu Dejene , Edosa Dejene , Legesse Elsabeth , Nigusie Tadesse , Beya Moges , Mulatu Teshale 
Published: September 2022

Objective: The aim of this study is to assess the magnitude of sexual violence, its adverse reproductive health outcomes, and associated factors among female youth in the Northern Shoa zone, Oromia region, Ethiopia. Methods: A community-based cross-sectional study design was employed among 590 female youth from 1 December to 30 January 2021. A multi-stage sampling technique and a pretested structured interviewer-administered questionnaire were used. The data were entered into EpiData version 3.1 and then transferred to SPSS 23 for analysis. Descriptive statistical analysis was done, and an association between an outcome variable and independent variables was examined in logistic regression models. Results: According to the study, the respective rates of sexual violence and harmful sexual reproductive consequences were 20.7% and 11.9%. Sexual violence was significantly associated with alcohol consumption (adjusted odds ratio = 2.549, 95% confidence interval = (1.548, 4.195)) and childhood exposure to inter-parental violence (adjusted odds ratio = 1.66, 95% confidence interval = (1.002, 2.888)). Rural childhood residence (adjusted odds ratio = 0.037, 95% confidence interval = (0.007, 0.192)), fathers with college degrees (adjusted odds ratio = 0.037, 95% confidence interval = (0.013, 0.106)), and readiness for first sex (adjusted odds ratio = 0.073, 95% confidence interval = (0.028, 0.189)) were all independent predictors of adverse reproductive health outcomes. Conclusion: In this study, young females frequently experience sexual violence and poor reproductive health outcomes. Alcohol consumption and having experienced parental conflict as a child were found to be risk factors for sexual violence, while residing contracts during childhood, the father’s level of education, and willingness to engage in the first sexual encounter were linked to adverse reproductive health outcomes.
Geographies of grocery shopping in major Canadian cities: Evidence from large-scale mobile app data
Authors: Smith Lindsey G , Ma Maggie Yifei , Widener Michael J , Farber Steven 
Published: September 2022

Socioeconomic and place-based factors contribute to grocery shopping patterns which may be important for diet and health. Big data provide the opportunity to explore behaviours at the population level. We used data collected from Flipp, a free all-in-one savings and deals content app, to identify visitation to grocery stores and estimate home-to-store distances, monthly frequencies and number of unique stores visited in eight Canadian cities during 2020. Grocery shopping outcomes and associations with income, population density and percentage of car commuters were explored using data aggregated at the Aggregate Dissemination Area level in which app users lived. Changes in patterns of grocery shopping following restrictions implemented in response to the COVID-19 pandemic were also investigated. The median of average home-to-store distances ranged from 4 to 5 km across all cities throughout 2020. Shorter distances for grocery shopping were shown consistently for shoppers living in lower income, densely populated and low car-commuting ADAs. A maximum of three unique supermarkets were visited on average each month. Decreases in the frequency and variability of grocery store visits were shown across all cities in April 2020 following the implementation of restrictions in response to COVID-19, and pre-pandemic levels of shopping were rarely achieved by the end of the year. Ultimately, these results provide much needed information regarding the characteristics of grocery shopping trips in a high-income country, as well as how food shopping was impacted by the onset of the COVID-19 pandemic. This information will be useful for a range of future studies seeking to characterise access to food retail.
Displacement of the Metatarsal Sesamoids in Relation to First Metatarsophalangeal Joint Extension
Authors: French Mackenzie , Thorhauer Eric D. , Kimura Tadashi , Sangeorzan Bruce J. , Ledoux William R. 
Published: September 2022

Background: Quantifying normal sesamoid movement in relation to first metatarsophalangeal joint (MTPJ1) motion is essential to identifying aberrant kinematics and understanding how they may contribute to forefoot pain and dysfunction. The present study aims to report sesamoid displacement in relation to MTPJ1 extension and to compare sesamoid displacement with MTPJ1 range of motion (ROM) from several imaging modalities. Methods: Using 10 fresh frozen cadaveric feet, sesamoid displacement was evaluated during simulated MTPJ1 extension. The ability of 3 MTPJ1 measurement techniques (goniometry, fluoroscopy, and unloaded cone beam computed tomography [CBCT]) in predicting sesamoid displacement were compared. Kinematics were expressed in a coordinate frame based on the specimen-specific first metatarsal anatomy, and descriptive statistics are reported. Results: In the sagittal plane in both neutral and maximally extended positions, the tibial sesamoid was located on average more anteriorly than the fibular sesamoid. The angular displacement of the tibial and fibular sesamoids in the sagittal plane were 30.2 ± 14.3 degrees and 35.8 ± 10.6 degrees, respectively. In the transverse plane, both sesamoids trended toward the body midline from neutral to maximum extension. The intersesamoidal distance remained constant throughout ROM. Of the 3 measurement techniques, MTPJ1 ROM from CBCT correlated best ( R2 = 0.62 and 0.81 [ P < .05] for the tibial and fibular sesamoid, respectively) with sagittal plane sesamoid ROM. Conclusion: The sesamoids were displaced anteriorly and medially in relation to increasing MTPJ1 extension. CBCT was the most correlated clinical imaging technique in relating MTPJ1 extension with sesamoid displacement. Clinical Significance: This study advances our understanding of the biomechanical function of the sesamoids, which is required for both MTPJ1 pathology interventions and implant design. These findings support the use of low-dose CBCT as the information gathered provides more accurate detail about bone position compared with other imaging methods.
Chlamydia pneumoniae is Prevalent in Symptomatic Coronary Atherosclerotic Plaque Samples Obtained From Directional Coronary Atherectomy, but its Quantity is Not Associated With Plaque Instability: An Immunohistochemical and Molecular Study
Authors: Otani Tomoyuki , Nishihira Kensaku , Azuma Yoshinao , Yamashita Atsushi , Shibata Yoshisato , Asada Yujiro , Hatakeyama Kinta 
Published: September 2022

Aim: To clarify whether there is any association between the extent of Chlamydia pneumoniae (C. pneumoniae) infection and plaque instability or post–directional coronary atherectomy (DCA) restenosis, we determined the frequency of C. pneumoniae infection and its localization in symptomatic coronary atherosclerotic plaques using specimens obtained from DCA. Methods and results: Immunohistochemistry (IHC) and real-time polymerase chain reaction (RT-PCR) revealed the existence of C. pneumoniae in all 50 specimens of coronary atherosclerotic plaques obtained by DCA. C. pneumoniae–positive cell ratio determined with IHC or copy numbers of C. pneumoniae DNA detected by RT-PCR did not differ significantly between patients with stable angina pectoris and those with acute coronary syndrome (IHC: 16.4 ± 7.6% vs 18.0 ± 7.1%, P = .42; RT-PCR: no. of cases with high copy numbers 12/25 vs 10/25, P = .78), or between patients with subsequent post-DCA restenosis and those without (IHC: 17.1 ± 8.0% vs 18.0 ± 7.4%, P = .74; RT-PCR: 5/12 vs 10/21, P = 1.00). Conclusions: C. pneumoniae was highly prevalent in coronary atherosclerotic plaques of patients who underwent DCA. However, the extent of C. pneumoniae infection in coronary atherosclerotic plaques was not associated with plaque instability or post-DCA restenosis.
Divergent Effects of Laser Irradiation on Ensembles of Nitrogen-Vacancy Centers in Bulk and Nanodiamonds: Implications for Biosensing
Authors: Olivares-Postigo Domingo , Gorrini Federico , Bitonto Valeria , Ackermann Johannes , Giri Rakshyakar , Krueger Anke , Bifone Angelo 
Published: September 2022

AbstractEnsembles of negatively charged nitrogen-vacancy centers (NV−) in diamond have been proposed for sensing of magnetic fields and paramagnetic agents, and as a source of spin-order for the hyperpolarization of nuclei in magnetic resonance applications. To this end, strongly fluorescent nanodiamonds (NDs) represent promising materials, with large surface areas and dense ensembles of NV−. However, surface effects tend to favor the less useful neutral form, the NV0 centers, and strategies to increase the density of shallow NV− centers have been proposed, including irradiation with strong laser power (Gorrini in ACS Appl Mater Interfaces. 13:43221–43232, 2021). Here, we study the fluorescence properties and optically detected magnetic resonance (ODMR) of NV− centers as a function of laser power in strongly fluorescent bulk diamond and in nanodiamonds obtained by nanomilling of the native material. In bulk diamond, we find that increasing laser power increases ODMR contrast, consistent with a power-dependent increase in spin-polarization. Conversely, in nanodiamonds we observe a non-monotonic behavior, with a decrease in ODMR contrast at higher laser power. We hypothesize that this phenomenon may be ascribed to more efficient NV−→NV0 photoconversion in nanodiamonds compared to bulk diamond, resulting in depletion of the NV− pool. A similar behavior is shown for NDs internalized in macrophage cells under the typical experimental conditions of imaging bioassays. Our results suggest strong laser irradiation is not an effective strategy in NDs, where the interplay between surface effects and local microenvironment determine the optimal experimental conditions.