bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengelolaan Wakaf Produktif Dalam Bentuk Usaha Perikanan di Pondok Tidar Kota Magelang
Authors: Syamsuri Syamsuri , Bahrudin Bahrudin 
Published: August 2022

Pesantren sebagai lembaga pendidikan Islam yang berdiri dan didirikan bersama masyarakat untuk masyarakat dan oleh masyarakat. Sehingga keberadaan dan orientasi pesantren sangat erat dengan mashlahah dan manfaat untuk masyarakat pada umumnya. Dalam prespektif ekonomi, pengelolaan harta wakaf di pesantren merupakan salah satu instrument yang mampu menyelesaikan masalah social ekonomi masyarakat. Walau bagaimanapun, dalam pelaksanaannya masih didapati beberapa nadzir yang belum mampu mengembangkan bahkan mengelolanya untuk memberdayakan masyarakat sekitar.Penelitian ini bertujuan untuk menjelaskan bagaimana wakaf produktif dikelola dan dikembangkan oleh Pondok Tidar. Pondok Tidar dipilih sebagai tempat penelitian dengan menggunakan purposive sampling, karena dampak mauquf alaihnya yang telah diwujudkan melalui pemberian beasiswa kepada para santri yang dhuafa’, mengelola dan mengembangkan wakaf produktif yang dianggap berisko tinggi yaitu perikanan yang berbasis aset wakaf. Penelitian ini mengunakan metode kualitatif yang disajikan secara diskriptif analitik, dianalisa secara “triangulasi” dan sumber data melalui dokumentasi, observasi dan wawancara.Akhirnya penelitian ini mendapati bahwa PondokTidar telah melaksanakan prinsip-prinsip pemberdayaan ekonomi, baik dari segi perencanaan, pengorganisasian, pengelolaan sumberdaya manusia, kepemimpinan dan pengawasan, maka Pondok Tidar telah berhasil dalam mengelola dan mengembangkan wakaf secara produktif. Akan tetapi dalam pelaksanannya, Pondok Tidar mendapati beberapa hambatan yaitu personil SDM yang terbatas, pemahaman masyarakat tentang wakaf produktif. Dengan adanya penelitian ini diharapkan instisusi wakaf lebih kreatif dan inovatif dalam mengembangkan asset wakaf yang ada secara produktif dengan cara mengoptimalkan potensi yang ada baik dari SDM maupun kearifan local.
EFFECTIVENESS OF USING THE TIKTOK APPLICATION AS A DIGITAL DAKWAH MEDIA FOR GENERATION Z (STUDY OF TIKTOK ACCOUNTS @Basyasman00)
Authors: Rochmah Nur Hafifah 
Published: August 2022

Abstract: In this modern era, the existence of the use of social media has a significant influence on people's daily lives, especially Generation Z. This paper aims to determine the extent of the role of the Tiktok application as one of the platforms favored by Generation Z on the spread of values. Islamic valuesthrough the creator of the da'wah Husain Basyaiban. This research is included in the type of library research with a qualitative descriptive approach. The research data was obtained through direct observation on the TikTok account @Basyasman00 as well as documentation on uploaded posts to see the activities of netizens including the number of followers, likes, comments, shares and video views. Furthermore, the data collected was analyzed using a content analysis approach (content analysis). The results show that da'wah through the TikTok application is quite effective in reaching generation Z. The TikTok application is a surefire way to spread Islamic values today, especially for generation Z because of the great interest in knowledge about religion which is presented in a unique, interesting, and interesting way. and contemporary. The content that is in great demand by Gen Z is about solving the current issues that are booming as well as light topics that are closely related to the daily lives of teenagers. Keywords: TikTok, Generation Z, Digital Da'wah, Husain Basyaiban.
Morphine and dexamethasone-incorporated cocktail regimen for postoperative pain in patients undergoing primary total knee arthroplasty: a randomized controlled trial
Authors: Gong Ying , Gong Jian , Li Yuancheng , Liu Shi , Xu Cui 
Published: August 2022

Abstract
Background
This study was conducted to evaluate the pain-reducing efficacy and safety of morphine and dexamethasone-incorporated cocktail regimen in patients undergoing total knee arthroplasty (TKA).
Methods
This study enrolled 213 patients and randomly assigned them to one of three groups. Group I patients were injected with morphine, dexamethasone, bupivacaine, flurbiprofen axetil, and normal saline. Patients in group II were injected with dexamethasone, bupivacaine, flurbiprofen axetil, and normal saline. Patients in control group were administered bupivacaine, flurbiprofen axetil, and normal saline. To compare the pain-controlling efficiency, the visual analog scale (VAS) score, active and passive range of movement (ROM), rescue analgesia use, and 1-min walking distances were recorded and evaluated. Indicators of inflammation include serum C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) levels, and white blood cells count (WBC) were tested and compared. The following side effects were monitored: headache, dizziness, nausea, vomiting, wound leakage and wound infection.
Results
Group I patients had the lowest VAS and the highest active and passive ROM. In Group I, the VAS reduced from day one to four, but the ROM increased. Group II patients had a smaller reduction in VAS and a smaller increase in ROM, compared with the patients in control group. Patients in group I required the least rescue analgesia use in the first 48 hours postoperative and demonstrated the best walking abilities on postoperative day 2 and day 4. Indicators of inflammation were similar in all enrolled individuals. Following side effects were not recorded: headache, dizziness, nausea, and vomiting. Wound leakage was observed in four patients in group I (two patients) and group II (two patients). No wound infection symptoms were detected.
Conclusions
Morphine and dexamethasone-incorporated cocktail regimen efficiently reduced postoperative pain in patients undergoing primary TKA.
Trial registration:
Randomized controlled trial ISRCTN25027558, registered retrospectively on 27/02/2022. ( https://www.isrctn.com/ISRCTN25027558 )
Investigation on Prevalence of Canine Trypanosomiasis in the Conservation Areas of Bwindi-Mgahinga and Queen Elizabeth in Western Uganda
Authors: Ochieng James Robert , Bachs Marta Planellas , Nsubuga Anthony , Rwego Innocent B. , Kisakye John Joseph M. , Riba Laura Muro , Figueres Jesus Muro 
Published: August 2022

Abstract
Nowadays, despite the instauration of several control strategies, animal trypanosomiasis continues to be reported all over Uganda. Few canine African trypanosomiasis (CAT) studies have been carried out, yet dogs are known Trypanosoma reservoirs that share identical home ranges with livestock and serve as parasite link between livestock and humans. This study evaluates the prevalence of CAT in dogs in the Bwindi-Mgahinga and Queen Elizabeth conservation areas. This information will be useful to evaluate the possible role of dogs in the transmission cycle of Trypanosoma species in livestock and wild animals. Trypanosome tests using microhaematocrit centrifugation/dark ground microscopy technique (MHCT) followed by conventional polymerase chain reaction (cPCR) were performed in blood samples collected from identified indigenous dogs (n = 124). Four (3.23 %) out of 124 dogs were positive for CAT. One dog was positive with Trypanosoma congolense and three with T. vivax. There was no significant statistical difference in CAT prevalence rate in relation to dog’s age, sex and site (P > 0.05). This study reports what we believe is the first-time detection of T. congolense and T. vivax in the indigenous dogs found in the Bwindi-Mgahinga and Queen Elizabeth conservation areas in western Uganda. The noticed T. congolense and T. vivax could be responsible for both canine and animal trypanosomiasis and represents a serious threat to the livestock industry. Therefore, there is a need for continuous trypanosomiasis surveillance and integrated management in contiguity to wildlife reserves.
Quantum Error Mitigation by Pauli Check Sandwiching
Authors: Gonzales Alvin , Shaydulin Ruslan , Saleem Zain , Suchara Martin 
Published: August 2022

Abstract
We describe and analyze an error mitigation technique that uses multiple pairs of parity checks to detect the presence of errors. Each pair of checks uses one ancilla qubit to detect a component of the error operator and represents one layer of the technique. We build on the results on extended flag gadgets and put it on a firm theoretical foundation. We prove that this technique can recover the noiseless state under the assumption of noise not affecting the checks. The method does not incur any encoding overhead and instead chooses the checks based on the input circuit. We provide an algorithm for obtaining such checks for an arbitrary target circuit. Since the method applies to any circuit and input state, it can be easily combined with other error mitigation techniques. We evaluate the performance of the proposed methods using extensive numerical simulations on 1,850 random input circuits composed of Clifford gates and non-Clifford single-qubit rotations, a class of circuits encompassing most commonly considered variational algorithm circuits. We observe average improvements in fidelity of 34 percentage points with six layers of checks.
Polyamide membrane pretreatment combined with UPLC–MS/MS for the determination of industrial dyes in grain and meat products
Authors: He Yahui , Liu Xinyu , Zhu Yao , Liu Yajie , Li Lu , Wang Jing , El-Aty A. M. Abd 
Published: August 2022

Abstract
Herein, ultra-performance liquid chromatography-tandem four-stage mass spectrometry (UPLC–MS/MS) combined with a novel polyamide membrane extraction was used to rapidly determine industrial dyes in grain and meat products. Polyamide was used as an adsorbent in the membrane. When the sample was treated by the polyamide membrane, the industrial dyes were absorbed by the N-propyl Ethylenediamine (PSA) into the polyamide membrane, while most other ingredients were passed through the membrane. Then, the industrial dyes were eluted from the polyamide membrane by different solvents to be analyzed by UPLC–MS/MS. The novel pretreat method will reduce the time of the whole process to less than 30 minutes. The recovery of the dye was between 71% and 126%, and the precision was between 3 and 13. The results showed that the polyamide membrane can be used as a pretreatment method for detecting multicomponent industrial dyes in grain and meat products, which is rapid, simple, reliable and accurate.
Highly water-dispersed composite of cellulose nanofibers and boron nitride nanosheets
Authors: E Songfeng , Zhao Ruixia , Ning Doudou , Ma Qin , Geng Bo , Liu Jiayi , Lu Zhaoqing 
Published: August 2022

Abstract
In this work, a composite of cellulose nanofibers (CNFs) and boron nitride nanosheets (BNNSs) with high dispersity in water is prepared via the combination of ball-milling and high-pressure homogenization, which is then transformed into paper-like film by vacuum assisted filtering and drying. The obtained CNF/BNNS dispersions can stably exist over 30 days without the observation of sediments. CNFs as a medium of ball-milling can protect the exfoliated BNNSs from being reaggregation and severely destroyed in violent collisions, and the BNNSs and CNFs can promote their exfoliation with each other. The hydrophilicity and electrostatic repulsion of CNFs, as well as the strong interfacial interactions and stereo-hindrance effects between one-dimensional (1D) CNFs and two-dimensional (2D) BNNSs are the reasons for the high dispersity of the composite in water, which in turn results in the favorable mechanical properties of the formed films. Although the introduction of BNNSs lowers the stress, strain, and toughness of the neat CNF films, but increases their modulus due to the stiffness of BNNSs. However, the thermal conductivities of the homogenized samples are inferior to the unhomogenized ones, as the decreased lateral sizes and excellent dispersibility of BNNSs are unfavorable to the formation of connective path of thermal conduction.
Ranolazine attenuates brain inflammation in a rat model of type 2 diabetes
Authors: Cassano Velia , Tallarico Martina , Armentaro Giuseppe , De Sarro Caterina , Iannone Michelangelo , Leo Antonio , Russo Emilio , Citraro Rita , De Sarro Giovambattista , Hribal Marta Letizia , Sciacqua Angela 
Published: August 2022

Abstract
Recent studies suggest a pathogenetic association between metabolic disturbances, including type 2 diabetes (T2DM), and cognitive decline and indicate that T2DM may represent a risk factor for Alzheimer disease (AD). There are several experimental evidence that ranolazine, an antianginal drug, may act as a neuroprotective drug. The aim of the present study was to evaluate the effects of ranolazine on hippocampal neurodegeneration and astrocytes activation, in a T2DM rat model. Diabetes was induced by high fat diet (HFD) and streptozotocin (STZ) injection. Metformin, a widely employed hypoglycemic drug, has been used as positive control. Animals were divided into the following groups: HFD/STZ + Ranolazine, HFD/STZ + Metformin, HFD/STZ + Vehicle, NCD + Vehicle, NCD + Ranolazine, and NCD + Metformin. The presence of neurodegeneration was evaluated, in hippocampal cornus ammonis 1 (CA1) region, by cresyl violet staining histological methods, while astrocytes activation was assessed by Western blot analysis. Staining with cresyl violet highlighted a decrease in neuronal density and cell volume in the hippocampal CA1 area in of the diabetic HFD/STZ + Vehicle rats Ranolazine and Metformin both improved T2DM-induced neuronal loss and neuronal damage. Moreover, there was an increased expression of GFAP in HFD/STZ + Vehicle group, compared to either NCD and HFD/STZ animals receiving ranolazine or metformin. In conclusion, in the present study, we provided insights on the mechanisms through which ranolazine may counteract cognitive decline in diabetic patients.
The prognostic effect of chemosensitivity on brain metastases in small-cell lung cancer: A retrospective analysis
Authors: Ma Jintao , Meng Chunliu , Tian Jia , Ren Kai , Yan Meng , Xu Liming , Zhao Lujun , Wang Ping 
Published: August 2022

Abstract
Purpose: To investigate the prognostic differences between small-cell lung cancer (SCLC) patients with different chemosensitivity to first line chemotherapy who developed brain metastasis as first site of progression. Methods: Patients with brain metastases (BMs) after first-line treatment of SCLC in our hospital admitted from January 2012 to October 2020 were retrospectively analyzed. According to the time interval between the completion of first-line chemotherapy and the onset of BMs (TFI), the patients were divided into chemo-sensitive group (TFI ≥ 90 days, n = 145) and chemo-resistant group (TFI ＜ 90 days, n = 97). Survival time after the onset of brain metastasis (BM-OS), which was calculated from the diagnosis of brain metastases and overall survival (OS), which was calculated from the diagnosis of small-cell lung cancer, were analyzed in this study. Survival curves were plotted using Kaplan-Meier method and differences between groups were compared using the log-rank test. The Chi-square test or Fisher’s exact test was used to compare categorical variables. Results: In total, the median BM-OS and OS were 8.4 months and 18.2 months respectively. The median BM-OS in chemo-sensitive group was 8.8 months and it was 8.0 months in the chemo-resistant group (P = 0.538); and the median OS was 22.0 months and 15.6 months, respectively (P = 0.001). In patients without extracranial progression (n = 193), the median BM-OS in chemo-sensitive and chemo-resistant group were 9.4 months and 9.7 months (P = 0.947), and the median OS were 22.7 months and 16.3 months, respectively (P = 0.017). In patients with extracranial progression (n = 49), the median BM-OS were 5.4 months and 4.2 months (P = 0.161), and the median OS were 17.6 months and 12.3 months, respectively (P = 0.002). Conclusions: After the development of brain metastasis as the first site of progression following chemotherapy in small cell lung cancer, the prognosis of chemo-sensitive patients not necessarily superior to chemo-resistant patients, especially in patients without extracranial progression.
Abnormal Peripheral Blood Cell Counts in Neurofibromatosis Type 1
Authors: Nobeyama Yoshimasa , Yasuda Ken-ichi , Asahina Akihiko 
Published: August 2022

Abstract
Introduction:
Neurofibromatosis type 1 (NF1), also known as von Recklinghausen disease, is an autosomal dominant disease characterized by neurofibromas with infiltration of mast cells. Neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR) and basophil-to-lymphocyte ratio (BLR) are examined as markers for various diseases. However, these parameters have not yet been assessed for NF1. This study therefore examined these parameters in NF1 patients.
Methods
We recruited 153 NF patients (78 males, 75 females) and 51 control patients (31 males, 20 females). Complete blood counts were performed, then NLR, LMR, PLR and BLR were calculated.
Results
Neutrophil count was significantly higher in male NF1 patients than in male controls. Lymphocyte count was significantly lower in NF1 patients than in controls for both sexes. Monocyte count was significantly higher in male NF1 patients than in male controls. Basophil count was significantly higher in male NF1 patients than in male controls. NLR, PLR and BLR were significantly higher in NF1 patients than in controls for both sexes. LMR was significantly lower in NF1 patients than in controls for both sexes.
Conclusion
NF1 shows high NLR, PLR and BLR and low lymphocyte count and LMR.
Effect of benznidazole on cerebral microcirculation during acute Trypanosoma cruzi infection in mice
Authors: Gonzaga Beatriz Matheus Souza , Horita Samuel Iwao Maia , Beghini Daniela Gois , Gomes Fabiana , Nisimura Líndice Mitie , Santos Isabele Barbieri , Estato Vanessa , Araújo-Jorge Tania Cremonini , Garzoni Luciana Ribeiro 
Published: August 2022

Abstract
Central nervous system alterations was described in Chagas disease in both human and experimental models, leading to meningoencephalitis, stroke and cognitive impairment. Recently, our group demonstrated that acute infection by Trypanossoma cruzi leads to cerebral microvasculophaty in mice with endothelial dysfunction, capillary rarefaction, increased rolling and leukocyte adhesion. Only benznidazole and nifurtimox are available for clinical treatment, they have an efficiency of 80% in the acute phase and less than 20% in chronic phase. However, the effect of these drugs on brain microcirculation has not yet been evaluated. We hypothesized that early treatment with benznidazole could protect brain microcirculation during acute experimental Chagas disease. Swiss Webster mice were inoculated with 104 trypomastigotes forms of T. cruzi, and after 24 h they were treated with 50 or 100 mg/kg/day of benznidazole for 14 consecutive days. In untreated infected mice, we observed cerebral microvascular rarefaction, increase in leukocyte rolling and adhesion, reduced cerebral blood flow, and increased CD3 + and F4-80 + cells in brain tissue. Early treatment with benznidazole at 100mg/kg/day and 50mg/kg/day prevented the occurrence of the alterations mentioned. Here, we show that BZ is able to protect the microcirculation and reduced brain inflammation in acute experimental Chagas disease.
Estimates of Prevalence, Time-Trend, and Association of Smoking in Adults Living with HIV, HBV, and HCV (NHANES 1999–2018)
Authors: Yang Jie , Lin Jin-Long , Liu Jing , Jiang Xiao-Wen , Zhang Hao , Peng Lei 
Published: August 2022

Abstract
Although the smoking rate of HIV, HBV or HCV infected people is much higher than that of the general population, smoking cessation interventions have long been ineffective. Therefore, further understanding of the underlying social reasons behind the poor behavior of this population is needed. We aimed to examine the estimates of prevalence, time-trend, and association of smoking among people living with HIV, HBV, or HCV. This cohort was composed of 32,115 individuals from the National Health and Nutrition Examination Survey (NHANES 1999–2018). All adults aged 21–59 who self-reported smoking status and had been tested for HIV, HBV, and HCV were included in this analysis. The time trend analysis of smoking and quitting rates in different years of survey follow-up and different infected populations. Multivariable logistic regression analysis was used to identify the risk factors related to smoking behavior of HIV|HBV|HCV infected people. Overall, the smoking rates of the people infected HIV|HBV|HCV were 1.35–1.93 times higher from 1999 to 2018. Compared to smokers without HIV&HBV&HCV, smokers living with HIV|HBV|HCV were more likely to be older (aged 30–39, 9.92, 6.07 to 16.21; aged 40–49, OR = 3.51, CI = 2.49 to 4.94), more males (1.99, 1.54 to 2.55), lower education level (1.78, 1.39 to 2.29), lower economic level (2.05, 1.59 to 2.65), unemployed (1.63, 1.21 to 2.20), suffering depression (1.35, 1.05 to 1.72), and drug users (7.65, 5.04 to 11.59). Taken together, studies have shown that complex psychosocial characteristics and behavioral factors, including individual economic status, mental diseases (such as depression) and illegal drug use (such as marijuana and heroin) hinder their efforts to quit smoking. Therefore, it is very important to take targeted smoking cessation interventions to meet the unique situation and needs of this special group.
Establishment and Validation of the Nomogram Model for Mortality Risk in Patients with Dangerous Upper Gastrointestinal Bleeding
Authors: Liu Zhou , Zhang Liang , Bai Wen-hui , Cheng Li , Zhan Li-ying , Wang Pei-xue , Jiang Gui-jun , Dong Wei-guo 
Published: August 2022

Abstract
Objective A Nomogram model was established to predict the mortality risk for patients with dangerous upper gastrointestinal bleeding (DUGIB), aimed at identifying those high-risk one who required emergency treatment. Methods Collected the clinical data of 256 DUGIB patients who were admitted to Intensive Care Unit (ICU) of Renmin Hospital of Wuhan University from January 2020 to April 2022. A total of 179 patients admitted to ICU were treated as training cohort, while 77 patients who were admitted to ICU of East Campus were considered validation cohort. Multivariate logistic regression analysis was performed to determine the independent risk factors, and R packages were used to construct nomogram model. The prediction accuracy and identification ability were evaluated by receiver operating characteristic curve (ROC), C index and calibration curve. Furthermore, the clinical value of the model was evaluated by decision curve analysis (DCA). Simultaneously, the model was externally validated. Results A total of 256 patients diagnosed with DUGIB were included, among which 67 patients (19.14%) eventually died. Multivariate logistic regression analysis suggested that hematemesis, urea nitrogen level, emergency endoscopy, AIMS65 score, GBS and Rockall score were all independent risk factors. ROC curve analysis showed the area under the curve (AUC) of training cohort was 0.980 (95% CI : 0.962~0.997), while validation cohort was 0.790 (95% CI : 0.685~0.895). The calibration curves for both training and validation cohorts were then tested by Hosmer-Lemeshow Goodness ( P =0.778, P =0.516). To summarize, the Nomogram prediction model was of great clinical value. Conclusion The nomogram was proven to be an effective tool for the risk stratification of DUGIB patients, and was also helpful for the early identification and intervention, especially in ICU.