bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sosialisasi Pendidikan Seks Pada Anak Sejak Dini Di SDN 30 Kota Bima
Authors: Nurbayan ST , Waluyati Ida , Nurnazmi Nurnazmi , Azmin Nikman , Arifuddin Arifuddin , Tahir M. 
Published: April 2022

Maraknya pelecehan seksual yang terjadi di Kota dan Kabupaten Bima sangat meresahkan masyarakat karena dapat mengintimidasi dan merusak karakter dan secara sikologinya akan terganggu sepanjang perkembangannya. Data kekerasan dan pelecehan seksual sepanjang Tahun 2021 terdapat 14.517," kata Menteri PPPA I Gusti Ayu Bintang Darmawati dalam diskusi virtual, Rabu (19 Januari 2022). Kemudian di Kelurahan Nitu terdapat 14 anak dibawah umur yang menjadi korban pelecehan seksua. Reskrim Polres Bima Kota IPTU M Rayendra (2021) laporan kasus pelecehan seksual di Bima meningkat tajam pada bulan Juni 2021 di Kelurahan Nitu Kota Bima terdapat belasan siswi yang diduga dilecehkan dan dari hasil visum terdapat empat orang yang mengalami luka dibagian vital. Oleh karena itu perlu dilakukan sosialisasi pendidikan seks pada anak sejak dini dengan tujuan agar anak-anak manpu menjaga dirinya dan dapat menjaga otonomi tubuh mereka. Sasaran kegiatan ini adalah anak-anak yang berumur 11 samapai 12 tahun sebanyak 40 orang yang dibagi menjadi 2 kelompo. Metode yang digunakan terdiri dari 3 tahap yakni tahap awal dilakukan dengan menyusun jadwal, menetapkan tempat, mempersiapkan materi dan membentuk kelompok kegiatan, tahap pelaksanaan melakukan sosialisasi dengan pemberian materi dan tahap evaluasi dengan memberikan kuesioner yang sama seperti pada awal untuk memantau peningkatan pemahaman pendidikan seks sejak dini, otonomi tubuh. Adapun pencapaian hasil yang diharapkan terlaksananya kegiatan dan adanya peningkatan pemahaman anak untuk menerapkan pendidikan seks dan ketercapaiannya 75% peningkatan dari pertanyaan yang diajukan diawal.
Pengaruh Tunjangan Pegawai Terhadap Prestasi Kerja Pegawai Pada Dinas Pendidikan Pemuda Dan Olahraga Kabupaten Bima
Authors: Burhanuddin Burhanuddin , Arsad Arsad 
Published: April 2022

Penelitian ini beruujuan untuk mengetahui pengaruh tunjangan pegawai terhadap prestasi kerja pegawai pada Dinas Pendidikan Pemuda dan Olahraga Kabupaten Bima. Penelitian ini adalah penelitian korelasional. Instrumen dalam penelitian ini adalah kuisioner Alat analisis data yang digunakan adalah regresi liner sederhana. Sampel dalam penelitian ini adalah sebanyak 36 orang. Hasil penelitian, didapatkan bahwa terdapat pengaruh tunjangan pegawai terhadap prestasi kerja pegawai pada Dinas Pendidikan Pemuda dan Olahraga Kabupaten Bima, hal tersebut ditunjukkan oleh nilai thitung lebih besar dari nilai ttabel (3,519>2,000). Nilai koefisien korelasi sebesar 0,267. sedangkan besarnya pengaruh tunjangan pegawai terhadap prestasi kerja pegawai ditunjukkan dengan hasil koefisien diterminasi (r2) sebesar 0,267 atau 26,7%.
Pemanfaatan Kayu Apu (Pistia stratiotes) Untuk Mengukur Kadar Fosfat dan COD Pada Limbah Cair
Authors: Irma Rubianti  , Amran Amran 
Published: April 2022

Limbah memiliki dampak negatif yang ditimbulkan, pencemaran air yang disebabkan dari hasil proses cucian pakaian oleh adanya kandungan fosfat dan COD, sehingga menyebabkan kekeruhan dan menghalangi masuknya sinar matahari yang akan mengakibatkan terjadinya pencemaran air. Berdasarkan hasil pengujian air limbah dari salah satu usaha cucian (laundry) di rumah warga di daerah Penaraga Kota Bima diperoleh data kandungan COD sebesar 239,25 mg/L dan fosfat sebesar 16 mg/L. Kandungan COD dan fosfat ini melebihi baku mutu air limbah. Berdasarkan permasalahan yang ada, salah satu alternatif penyisihan COD dan fosfat yang mudah, murah, dan efektif adalah teknik fitoremediasi menggunakan tumbuhan kayu apu (Pistia stratiotes). Penelitian ini bertujuan untuk menganalisis efisiensi tumbuhan kayu apu dalam mengukur dan menurunkan kadar COD dan fosfat pada limbah cair. Metode yang digunakan adalah eksperimen skala laboratorium menggunakan wadah berupa ember plastik yang diisi air limbah 100%. Penelitian pendahuluan yang dilakukan adalah proses aklimatisasi tumbuhan selama 5 hari, selanjutnya dilakukan uji fitoremediasi selama 20 hari atau sampai tumbuhan mati. Hasil penelitian ini menunjukkan bahwa tumbuhan kayu apu mampu bertahan hanya sampai hari ke-7 dengan persentase COD dan fosfat pada air limbah sebesar 8,753%, 20,033%, dan 46,875%
Uji Organoleptik Tempe Dari Biji Asam (Tamarindus indica) Berdasarkan Waktu Fermentasi
Authors: Puspitasari Diana , Nasir Muh. , Azmin Nikman 
Published: April 2022

Penelitian ini bertujuan untuk mengetahui bagaimana warna, rasa, tekstur, dan aroma tempe dari biji asam dalam uji organoleptik berdasarkan waktu fermentasi. Dalam penelitian ini tempe biji asam difermentasikan menurut beberapa varian waktu yaitu 36 jam, 40 jam. Rancangan penelitian Menggunakan Rancangan Acak Legkap (RAL) dengan 2 perlakuan dan 3 ulangan, analisis data menggunakan uji organoleptik dengan menggunakan skala hedonik, sampel peneitian adalah ahli tataboga, dosen, dan mahasiswa. Berdasarkan hasil analisis data diketahui bahwa hasil terbaik dari warna, rasa dan tekstur tempe biji asam paling tinggi adalah pada waktu fermentasi 40 jam, sedangkan untuk aroma tempe biji asam paling tinggi pada waktu fermentasi 36 jam. Kesimpulannya kualitas dari tempe biji asam dipengaruhi oleh lamanya waktu fermentasi
Pemanfaatan Rumput Laut (Eucheuma cottonii) Sebagai Bahan Dasar Masker Wajah Alami
Authors: Sari Nurmala , Bakhtiar Bakhtiar , Azmin Nikman 
Published: April 2022

Penelitian tentang pemanfaatan rumput laut bertujuan untuk mengetahui pengaruh masker alami yang terbuat dari rumput laut Eucheuma cottonii terhadap kulit wajah. Pembuatan masker alami dilakukan dengan menentukan berat masing-masing bahan dasar alami untuk membentuk struktur pasta. Tekhnik pengambilan data diperoleh dari hasil wawancara berupa pertanyaan yang di ajukan pada responden yang telah menggunakan masker rumput laut. Penelitian ini menggunakan metode deskriptif kualitatif dan deskriptif kuantitatif. Hasil penelitian menunjukkan bahwa pengaruh masker alami wajah dari rumput laut pada 20 responden pemakai terdapat 6 responden mengalami perubahan BB (Banyak Berkurang) sebanyak 24%, 7 responden yang mengalami perubahan SB (Sedikit Berkurang) sebanyak 21%, 4 responden mengalami perubahan TB(Tidak Berkurang) sebanyak 4% dan 3 responden mengalami perubahan ST(Sangat Tidak Berkurang) sebanyak 0%.
KOLABORASI PEMERINTAH PUSAT DAN DAERAH DALAM PENGEMBANGAN KAWASAN EKONOMI KHUSUS (KEK) DI INDONESIA
Authors: Silsila Asri  , Yahya Krisnawansyah  
Published: April 2022

The development of special economic areas (KEK) of local governments collaborates with the central government and private parties. The development of a region into a special economic area requires a real planning and action. Supported by regional autonomy demanding the role of local governments in realizing the SNR, it also requires collaboration with the central government in addition to the large role of the private sector in economic activity. Government and private cooperation with Indonesia's infrastructure development model involves the private sector, local government, central government in a synergy with their respective roles and functions that allow for a clear division of positions, duties and responsibilities set out within the legal framework of legal in carrying out development projects. The strategy that can be pursued by local governments in realizing SNR is to build collaboration with private parties and central government in public private partnership schemes.
Keywords: Collaboration, Special Economic Zones, Development
A Stochastic Network Approach to Modelling Ship Evacuation
Authors: Capizzi V , Marian R 
Published: April 2022

This paper presents a development of a novel, efficient, and robust tool to conduct evacuation from maritime ships using multi-commodity network theory and graph search techniques. MSC/1533 (IMO, 2016) presents guidelines to conduct simplified/quasi-advanced analysis methods for the evacuation analysis of ships. The IMO techniques describe a prescriptive approach and don’t consider path variabilities or uncertainties associated with the dynamic nature of the evacuation environment. To enhance the work presented by the IMO, a linear programming multi-commodity graphing solution has been developed and implemented in Excel. This model is based on network and graph theory and specifies basic passenger characteristics, simulates ships geometry and specifies path constraints. The simulation determines the shortest route to the nearest safe point/muster station. Monte Carlo is used to characterise model uncertainties in the simulation. Initial experiments indicate this technique is feasible. As a Systems Engineering tool, it can be used in trade-off studies to finalise ship layout design and identify path delay/choke points and can be used to rank evacuation performance of existing ship configurations.
Genetic Diversity and Molecular Surveillance of Antimalarial Drug Resistance of Plasmodium falciparum among Hospitals Patients in Benue State Nigeria
Authors: Adulugba O. A. , Amali O. , Manyi M. M. , Ikpa T. F. , Obisike V. U. 
Published: April 2022

Introduction: Malaria is a febrile illness caused by parasites of the genus Plasmodium and transmitted by female Anopheles mosquitoes. The genetic diversity and antimalarial drug resistance of Plasmodium falciparum are some of the major challenges of malaria control programme in Nigeria.
Aim: This study was aimed at determining the genetic diversity, and molecular surveillance of antimalarial drug resistance among patients attending Government hospitals in Benue State, Nigeria.
Methodology: Plasmodium falciparum deoxyribonucleic acid was extracted from dried blood spots of 60 positive malariacases among the patients. The diversity of Plasmodium falciparum was done by genotyping 3D7 and FC27 families of merozoite surface protein- 2 alleles. The Plasmodium falciparum multidrug resistance 1 and Plasmodium falciparum kelch13 genes of Plasmodium falciparum were also amplified and assessed by restriction fragment length polymorphism (RFLP) to survey molecular resistance to antimalarial drugs.
Results: The results showed that the frequency of 3D7 allele 37(61.7%) was higher than FC27 allele 18(30.0%). The frequency of merozoite surface protein- 2 infections with both allelic types was 5(8.3%). There was a significant difference in the distribution of the merozoite surface protein two alleles (χ2=25.9,df=2 P<.0.001). Both the Plasmodium falciparum multidrug resistance 1 Asparagine 86Tyrosine (N86Y) and Aspartic acid 1246Tyrosine (D1246Y), had 100 % mutant while the 100% while the Plasmodium falciparum kelch13 G449A had 100% wild type allele.
Conclusion: The current study underscores the need for frequent monitoring of indicators of antimalaria drug resistance in Nigeria.
Single Conjugated Polymer with Four Stepwise HOMO Levels for Effective Hole Injection Across Large Barrier 1.4 eV to Core–Shell Quantum Dot Layer for Electroluminescence in Inverted QLED
Authors: Wu Shuo‐En , Sharma Sunil , Chen Hsin‐Lung , Chen Show‐An , Komarov Pavel V. , Ivanov Viktor A. , Khokhlov Alexei R. 
Published: April 2022

AbstractA novel graded‐HOMO‐level hole transport polymer (g‐HTP) is proposed for the first time with spiro‐polyfluorene (sPF) as the main chain and the three hole‐transporting moieties triphenyl amine (TPA), carbazole (Cz), and N,N′‐dicarbazolyl‐3,5‐benzene (mCP) as side chains for effective hole injection across the large barrier 1.4 eV into the green‐emission core–shell quantum dot (QD) CdSe/ZnS emission layer in inverted QD light‐emitting diode (i‐QLED): ITO/ZnO/QD/HTP/MoO3/Al, in which both oleophilic ligands (OA and TOP) in the QD are partially removed from QD surface by annealing at 270 °C for preventing dissolution by solvent in subsequent coating of hole transport material (HTM) solutions atop and also improving electron and hole mobilities, especially the former. The proposed g‐HTP with various m:n mole ratios of mCP to TPA/Cz moieties along with various reported HTMs (PVK, Poly‐TPD and TFB) are investigated. Among them, the proposed g‐HTP with the comonomer mole ratio 1:1 gives the best performance ηmax 36.1 cd A−1 and Bmax 208 600 cd m−2, which is the highest performance among the reported i‐QLEDs with single hole‐transport layer ever documented. In addition, its efficiency roll off is low from 35.8 cd A−1 at 10 000 cd m−2 to 31.1 cd A−1 at 100 000 cd m−2.
Tyrosine Kinase Inhibitor discontinuation in Chronic Myeloid Leukemia: eligibility criteria and predictors of success
Authors: Inzoli Elena , Aroldi Andrea , Piazza Rocco , Gambacorti‐Passerini Carlo 
Published: April 2022

AbstractTKI discontinuation proved to be safe and feasible in patients with CML with deep and durable molecular responses, introducing an additional treatment goal for these patients beyond overall survival. However, treatment interruption is a safe procedure only with appropriate patient selection and monitoring. Clinical and biological factors associated with better outcomes do not yet offer a precise stratification of patients according to their risk of relapse. This article aims at reviewing the leading studies present in the field in order to define eligibility criteria for discontinuation and predictors of success.
Prediction of survival with intensive chemotherapy in acute myeloid leukemia
Authors: Sasaki Koji , Ravandi Farhad , Kadia Tapan , DiNardo Courtney , Borthakur Gautam , Short Nicholas , Jain Nitin , Daver Naval , Jabbour Elias , Garcia‐Manero Guillermo , Khoury Joseph , Konoplev Sergej , Loghavi Sanam , Patel Keyur , Montalban‐Bravo Guillermo , Masarova Lucia , Konopleva Marina , Kantarjian Hagop 
Published: April 2022

AbstractProgress with intensive chemotherapy and supportive care measures has improved survival in newly diagnosed acute myeloid leukemia (AML). Predicting outcome helps in treatment decision making. We analyzed survival as the treatment endpoint in 3728 patients with newly diagnosed AML treated with intensive chemotherapy from 1980 to 2021. We divided the total study group (3:1 basis) into a training (n = 2790) and a validation group (n = 938). The associations between survival and 27 characteristics were investigated. In the training cohort, the multivariate analysis identified 12 consistent adverse prognostic variables independently associated with worse survival: older age, therapy‐related myeloid neoplasm, worse performance status, cardiac comorbidity, leukocytosis, anemia, thrombocytopenia, elevated creatinine and lactate dehydrogenase, cytogenetic abnormalities, and the presence of infection at diagnosis except fever of unknown origin. We categorized patients into four prognostic groups, favorable (7%), intermediate (43%), poor (39%), and very poor (11%) with estimated 5‐year survival rates of 69%, 36%, 13%, and 3% respectively (p < .001). The predictive model was validated in an independent cohort. In a subset of patients with molecular mutation profiles, adding the mutation profiles after accounting for the effects of previous factors identified NPM1 (favorable), PTPN11, and TP53 (both unfavorable) mutations as molecular prognostic factors. The new proposed predictive model for survival with intensive chemotherapy in patients with AML is robust and can be used to advise patients regarding their prognosis, to modify therapy in remission (e.g., proposing allogeneic stem cell transplantation in first remission), and to compare outcome and benefits on future investigational therapies.
Syntheses of Covalent Organic Frameworks via a One‐Pot Suzuki Coupling and Schiff's Base Reaction for C2H4/C3H6 Separation
Authors: Han Xiang‐Hao , Gong Ke , Huang Xin , Yang Jian‐Wei , Feng Xiao , Xie Jing , Wang Bo 
Published: April 2022

AbstractCovalent organic frameworks (COFs) featuring permanent porosity, designable topologies, and tailorable functionalities have attracted great interest in the past two decades. Developing efficient modular approaches to rationally constructing COFs from a set of molecules via covalent linking has been long pursued. Herein, we report a facile one‐pot strategy to prepare COFs via an irreversible Suzuki coupling reaction followed by a reversible Schiff's base reaction without the need for intermediate isolation. Gram‐scale ordered frameworks with kgm topology and rich porosities can be obtained by using diamino‐aryl halide and dialdehyde aryl‐borate compounds as monomers. The resultant microporous CR‐COFs were used for efficient C2H4/C3H6 separation. This strategy reduces the waste generated and efforts consumed by stepwise reactions and relative purification processes, making the large‐scale syntheses of stable COFs feasible. Moreover, it offers a novel modular approach to designing COF materials.
Divergent Asymmetric Synthesis of Panowamycins, TM‐135, and Veramycin F Using C−H Insertion with Donor/Donor Carbenes
Authors: Bergstrom Benjamin D. , Merrill Amy T. , Fettinger James C. , Tantillo Dean J. , Shaw Jared T. 
Published: April 2022

AbstractPanowamycins are a group of isochroman‐based natural products first isolated from Streptomyces sp. K07‐0010 in 2012 by Satoshi Ōmura and co‐workers that exhibit modest anti‐trypanosomal activity. Herein we demonstrate the first syntheses of these natural products and their epimers. Stereoselective dirhodium‐catalyzed C−H insertion reactions with a donor/donor carbene construct the substituted isochroman core in the key bond‐forming step. The syntheses are completed without the use of protecting groups and feature a late‐stage Wacker oxidation. Incongruent NMR spectra between natural and synthetic samples revealed the structural misassignment of panowamycin A and veramycin F. Computational NMR studies suggested panowamycin A to be an alternate diastereomer, which was confirmed by synthesizing this isomer. Concurrent with this work, in 2021 Mahmud and co‐workers came to the same conclusion with an updated NMR analysis of panowamycin A. In a divergent, asymmetric sequence, we report the synthesis of panowamycin A, panowamycin B, TM‐135, and veramycin F.
Direct and Simultaneous Identification of Multiple Mitochondrial Reactive Oxygen Species in Living Cells Using a SERS Borrowing Strategy
Authors: Lin Shichao , Ze Huajie , Zhang Xia‐Guang , Zhang Yue‐Jiao , Song Juan , Zhang Huimin , Zhong Han‐Liang , Yang Zhi‐Lan , Yang Chaoyong , Li Jian‐Feng , Zhu Zhi 
Published: April 2022

AbstractIdentification of different mitochondrial reactive oxygen species (ROS) simultaneously in living cells is vital for understanding the critical roles of different ROS in biological processes. To date, it remains a great challenge to develop ROS probes for direct and simultaneous identification of multiple ROS with high specificity. Herein, we report a SERS‐borrowing‐strategy‐based nanoprobe (Au@Pt core–shell nanoparticles) for simultaneous and direct identification of different ROS by their distinct Raman fingerprints. Isotope substitution experiments and DFT calculations confirmed the ability of Au@Pt nanoprobe to capture and identify different mitochondrial ROS (i.e. ⋅OOH, H2O2, and ⋅OH). When functionalized with triphenylphosphine (TPP), the Au@Pt‐TPP nanoprobe located to mitochondria and detected multiple ROS simultaneously in living cells under oxidative stimulation. Our method offers a new tool for the study of the functions of various ROS in biological processes.
Chemically Bonded α‐Fe2O3/Bi4MO8Cl Dot‐on‐Plate Z‐Scheme Junction with Strong Internal Electric Field for Selective Photo‐oxidation of Aromatic Alcohols
Authors: Zhu Zijian , Huang Hongwei , Liu Lizhen , Chen Fang , Tian Na , Zhang Yihe , Yu Han 
Published: April 2022

AbstractInferior contact interface and low charge transfer efficiency seriously restrict the performance of heterojunctions. Herein, chemically bonded α‐Fe2O3/Bi4MO8Cl (M=Nb, Ta) dot‐on‐plate Z‐scheme junctions with strong internal electric field are crafted by an in situ growth route. Experimental and theoretical results demonstrate that the internal electric field provides a powerful driving force for vectorial migration of photocharges between Bi4MO8Cl and α‐Fe2O3, and the interfacial Fe−O bond not only serves as an atomic‐level charge flow highway but also lowers the charge transfer energy barrier, thereby accelerating Z‐scheme charge transfer and realizing effective spatial charge separation. Impressively, α‐Fe2O3/Bi4MO8Cl manifests a significantly improved photocatalytic activity for selective oxidation of aromatic alcohols into aldehydes (Con. ≥92 %, Sel. ≥96 %), with a performance improvement of one to two orders of magnitude. This work presents atomic‐level insight into interfacial charge flow steering.
Photoelectrochemical Nitrate Reduction to Ammonia on Ordered Silicon Nanowire Array Photocathodes
Authors: Kim Hyo Eun , Kim Jeehye , Ra Eun Cheol , Zhang Hemin , Jang Youn Jeong , Lee Jae Sung 
Published: April 2022

AbstractAs a new path to “green” ammonia production, photoelectrochemical nitrate reduction reaction (PEC NO3RR) is investigated for the first time. An Au‐decorated ordered silicon nanowire (O_SiNW) array photocathode demonstrates 95.6 % of Faradaic efficiency (FE) to ammonia at 0.2 VRHE, which represents a more positive potential than the thermodynamic reduction potential of nitrate by utilizing photovoltage. The high FE is possible because both Si and Au surfaces are inactive for competing water reduction to hydrogen. The O_SiNW array structure is favorable to promote the PEC NO3RR relative to planar Si or randomly‐grown Si nanowire, by enabling the uniform distribution of small Au nanoparticles as an electrocatalyst and facilitating the mass transport during the reaction. The results demonstrate the feasibility of PEC nitrate conversion to ammonia and would motivate further studies and developments.
Robust Self‐Assembled Molecular Passivation for High‐Performance Perovskite Solar Cells
Authors: Guo Haodan , Fang Yanyan , Cheng Hong‐Bo , Wu Jinpeng , Lei Yan , Wang Shumao , Li Xiangrong , Dai Yuhua , Xiang Wanchun , Xue Ding‐Jiang , Lin Yuan , Hagfeldt Anders 
Published: April 2022

AbstractDefect passivation via post‐treatment of perovskite films is an effective method to fabricate high‐performance perovskite solar cells (PSCs). However, the passivation durability is still an issue due to the weak and vulnerable bonding between passivating functional groups and perovskite defect sites. Here we propose a cholesterol derivative self‐assembly strategy to construct crosslinked and compact membranes throughout perovskite films. These supramolecular membranes act as a robust protection layer against harsh operational conditions while providing effective passivation of defects from surface toward inner grain boundaries. The resultant PSCs exhibit a power conversion efficiency of 23.34 % with an impressive open‐circuit voltage of 1.164 eV. The unencapsulated devices retain 92 % of their initial efficiencies after 1600 h of storage under ambient conditions, and remain almost unchanged after heating at 85 °C for 500 h in a nitrogen atmosphere, showing significantly improved stability.