bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review of Techniques for Measuring the Biot Coefficient and Other Effective Stress Parameters for Fluid-Saturated Rocks
Authors: Kasani Hossein A. , Selvadurai A. P. S. 
Published: October 2022

Abstract
Predicting the behavior of a saturated rock with variations in pore fluid pressure during geo-energy production and storage, deep geological disposal of nuclear wastes, etc. with skeletal mechanical behavior in the linear elastic range is carried out using the isothermal theory of poroelasticity that incorporates Biot's effective stress principle. For conditions that are not within linear elasticity, other effective stress coefficients are used. Several experimental methods for determining Biot's and other effective stress coefficients have been documented in the literature. The objective of this study is to review the fundamentals of these techniques, their advantages and disadvantages, and to include several case studies. Current techniques for Biot's coefficient are based on different premises: jacketed and unjacketed bulk moduli or compressibility values; volume changes of the bulk and pore fluid from a drained triaxial test on a saturated sample; isotropic-isochoric compression tests on a saturated sample; matching volumetric strains for dry and saturated samples; estimation of the Biot coefficient from other poroelastic parameters; and approximation of the jacketed bulk modulus from ultrasonic wave velocities and/or unjacketed bulk modulus from the mineralogical compositions. Other effective stress coefficients are based on matching failure envelopes for dry and saturated samples and variations of rock properties (such as volumetric strain, permeability, and ultrasonic wave velocities) with respect to confining stress and pore pressure. This article discusses variations in Biot's and other effective stress coefficients produced using the different techniques and how factors such as pore geometry, test conditions, stress path, and test temperature affect the coefficients.
Design of Control Schedules for Interturbine Burner Turbofan Engine Considering Ignition and Flameout Characteristics
Authors: Jia Xingyun , Zhou Dengji , Cao Mingdong , Hao Jiarui , Li Gangtuan , Ma Shixi , Huang Hongchao , Xu Luyao , Mo Zhihan , Qiang Xingyu 
Published: October 2022

Abstract
The interturbine burner (ITB) engine, which is introduced between high and low pressure turbines (LPTs), is a relatively new concept for increasing specific thrust and lowering high altitude specific fuel consumption (SFC) than engine with afterburner (AB). Although ITB engines have outstanding performance improvements, they also present a challenge to the design of control laws for ITB engines under unknown matching mechanisms and multiple constraints. This study proposes a self-scheduling control law design method for ITB engine mode transition that considers ITB ignition and flameout characteristics, as well as cooling air volume. This method derives the control law based on the global optimal algorithm and shapley additive explanation (SHAP)-value analysis method, which avoids manual analysis and reduces the number of adjustment of variable geometric components. An ITB transient model is established to verify the control laws under the transition of ignition and flameout modes. During the mode transition process of opening and closing the ITB, the flow fluctuation of the precritical point and rear-critical point does not exceed 2%, and the comprehensive thrust fluctuation index composed of three typical state points does not exceed 5%. Through simulation analysis with constrained constraints, at most one variable geometry component is adjusted.
Effect of Vanadium on the Microstructure, Transformation Temperatures, and Corrosion Behavior of NiTi Shape Memory Alloys
Authors: Sampath Santosh , Vedamanickam Sampath 
Published: October 2022

Abstract
Ni50Ti50-xVx (x = 0, 1, 2, 3 at%) shape memory alloys were prepared by vacuum induction melting. They were homogenized and then hot rolled. Carbon hydrogen nitrogen oxygen sulfur (CHNOS) and X-ray diffraction (XRD) analyses were carried out on the alloys to find out the oxygen and carbon contents and the phases present in the alloys. Transformation temperatures determined by differential scanning calorimetry indicate that the addition of vanadium reduces the transformation temperatures. Corrosion studies were carried out in Hanks’ solution, while potentiodynamic polarization tests were done to calculate the rate of corrosion of the alloys. Two significant parameters were analyzed from the Tafel graph, namely, corrosion rate and corrosion potential. A comparison of these properties of the alloys was also made with commercially pure titanium and binary NiTi alloys. Among the NiTiV alloys, Ni50Ti47V3 (at%) alloy was found to undergo the least rate of corrosion. With the increasing vanadium content, the rate of corrosion was found to decrease. Scanning electron microscopy (SEM) analysis of the corroded surface shows that pitting was the main mechanism of corrosion in these alloys. Results show that the addition of V to NiTi has a positive effect on the corrosion properties of the alloys. Elaborate results are discussed in detail in this article.
Key learnings from an outcome and embedded process evaluation of a direct to beneficiary mobile health intervention among marginalised women in rural Bihar, India
Authors: Irani Laili , Verma Supriya , Mathur Ruchika , Verma Raj Kumar , Mohan Diwakar , Dhar Diva , Seth Aaditeshwar , Chaudhuri Indrajit , Chaudhury Mahua Roy , Purthy Apolo , Nanda Ankit , Singh Shivani , Gupta Akshay , LeFevre Amnesty Elizabeth 
Published: October 2022

IntroductionMobile Vaani was implemented as a pilot programme across six blocks of Nalanda district in Bihar state, India to increase knowledge of rural women who were members of self-help groups on proper nutrition for pregnant or lactating mothers and infants, family planning and diarrhoea management. Conveners of self-help group meetings, community mobilisers, introduced women to the intervention by giving them access to interactive voice response informational and motivational content. A mixed methods outcome and embedded process evaluation was commissioned to assess the reach and impact of Mobile Vaani.MethodsThe outcome evaluation, conducted from January 2017 to November 2018, used a quasi-experimental pre–post design with a sample of 4800 married women aged 15–49 from self-help group households, who had a live birth in the past 24 months. Surveys with community mobilisers followed by meeting observations (n=116), in-depth interviews (n=180) with self-help group members and secondary analyses of system generated data were conducted to assess exposure and perceptions of the intervention.ResultsFrom the outcome evaluation, 23% of women interviewed had heard about Mobile Vaani. Women in the intervention arm had significantly higher knowledge than women in the comparison arm for two of seven focus outcomes: knowledge of how to make child’s food nutrient and energy dense (treatment-on-treated: 18.8% (95% CI 0.4% to 37.2%, p<0.045)) and awareness of at least two modern spacing family planning methods (treatment-on-treated: 17.6% (95% CI 4.7% to 30.5%, p<0.008)). Women with any awareness of Mobile Vaani were happy with the programme and appreciated the ability to call in and listen to the content.ConclusionLow population awareness and programme exposure are underpinned by broader population level barriers to mobile phone access and use among women and missed opportunities by the programme to improve targeting and programme promotion. Further research is needed to assess programmatic linkages with changes in health practices.
Assessment of the lifetime prevalence and incidence of induced abortion and correlates among female sex workers in Mombasa, Kenya: a secondary cohort analysis
Authors: Simmelink Anne Marieke , Gichuki Caroline M , Ampt Frances H , Manguro Griffins , Lim Megan S C , Agius Paul , Hellard Margaret , Jaoko Walter , Stoové Mark A , L'Engle Kelly , Temmerman Marleen , Gichangi Peter , Luchters Stanley 
Published: October 2022

IntroductionPrevalence of lifetime-induced abortion in female sex workers (FSWs) in Kenya was previously estimated between 43% and 86%. Our analysis aimed at assessing lifetime prevalence and correlates, and incidence and predictors of induced abortions among FSWs in Kenya.MethodsThis is a secondary prospective cohort analysis using data collected as part of the WHISPER or SHOUT cluster-randomised trial in Mombasa, assessing effectiveness of an SMS-intervention to reduce incidence of unintended pregnancy. Eligible participants were current FSWs, 16–34 years and not pregnant or planning pregnancy. Baseline data on self-reported lifetime abortion, correlates and predictors were collected between September 2016 and May 2017. Abortion incidence was measured at 6-month and 12-month follow-up. A multivariable logistic regression model was used to assess correlates of lifetime abortion and discrete-time survival analysis was used to assess predictors of abortions during follow-up.ResultsAmong 866 eligible participants, lifetime abortion prevalence was 11.9%, while lifetime unintended pregnancy prevalence was 51.2%. Correlates of lifetime abortions were currently not using a highly effective contraceptive (adjusted OR (AOR)=1.76 (95% CI=1.11 to 2.79), p=0.017) and having ever-experienced intimate partner violence (IPV) (AOR=2.61 (95% CI=1.35 to 5.06), p=0.005). Incidence of unintended pregnancy and induced abortion were 15.5 and 3.9 per 100 women-years, respectively. No statistically significant associations were found between hazard of abortion and age, sex work duration, partner status, contraceptive use and IPV experience.ConclusionAlthough experience of unintended pregnancy remains high, lifetime prevalence of abortion may have decreased among FSW in Kenya. Addressing IPV could further decrease induced abortions in this population.Trial registration numberACTRN12616000852459.
Association between serum alkaline phosphatase and bacteraemia in haemodialysis outpatients: a multicentre retrospective cross-sectional study
Authors: Katasako Aya , Sasaki Sho , Raita Yoshihiko , Yamamoto Shungo , Tochitani Kentaro , Murakami Minoru , Nishioka Ryo , Fujisaki Kiichiro 
Published: October 2022

ObjectivesElevated baseline serum alkaline phosphatase (ALP) may correlate with higher medium-term to long-term mortality in the general population and in patients with chronic kidney disease. However, few data are available on the association between serum ALP and the short-term prognosis of patients on haemodialysis (HD). We verified the association of ALP levels and bacteraemia or death in maintenance HD patients suspected of bacteraemia in an outpatient setting.DesignWe analysed 315 consecutive HD patients suspected of having bacteraemia with two sets of blood culture drawn on admission.SettingAdmission to two tertiary-care university medical centres from January 2013 to December 2015.ParticipantsConsecutive cases on maintenance HD aged≥18 years. Cases of hospitalised patients who had been transferred from another hospital, had a dialysis vintage<2 months, were also undergoing peritoneal dialysis, and/or were receiving HD less than once a week were excluded.Primary and secondary outcome measuresPrimary outcome measure was bacteraemia and secondary outcome was in-hospital death.ResultsAmong 315 cases included in the study, 187 had baseline-measured ALP levels, with a cut-off value on ROC analysis of 360 U/L (Area Under the Curve (AUC) 0.60, sensitivity 0.49, specificity 0.76). In multivariate analysis, there was a statistically significant association between a higher ALP in hospital visit and bacteraemia (OR: 2.37, 95% CI: 1.17 to 4.83). However, there were no statistically significant associations between higher ALP and in-hospital death (OR: 1.20, 95% CI: 0.57 to 2.54). A sensitivity analysis of 187 patients with no missing ALP values also demonstrated a significant association between elevated ALP and bacteraemia, but no significant association between ALP and in-hospital death.ConclusionsElevated ALP is a predictor of bacteraemia. In HD patients suspected of bacteraemia in outpatient settings, increased ALP levels were associated with increased likelihood of confirmed disease.
Instruments to measure postintensive care syndrome: a scoping review protocol
Authors: Chu Yuan , Timmins Fiona , Thompson David , Eustace-Cook Jessica 
Published: October 2022

IntroductionThere is an increasing need for evaluating postintensive care syndrome in adults concerning their long-term physical, psychological, cognitive and/or social outcomes, yet there is no consensus regarding the choice of instruments to measure these. This scoping review aims to identify and examine instruments used to measure postintensive care syndrome in adults.Methods and analysisThis scoping review will be conducted following the Arksey and O’Malley and its extended framework, and the Joanna Briggs Institute guideline. It will be reported according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses extension for Scoping Review checklists. Medline via EBSCO, CINAHL complete, EMBASE, Web of Science, AME and APA PsycINFO databases and grey literature will be searched from 2010 to the present. Reference lists of included studies will be manually checked to identify additional sources. The quality of included studies will be appraised using the Crowe Critical Appraisal Tool. All review steps will involve at least two reviewers. Data charting will be performed narratively, comprising study characteristics and findings, and instrument properties. This review will also aim to identify research gaps.Ethics and disseminationThere is no ethics disclosure for this review protocol. This scoping review will identify instruments used to measure postintensive care syndrome in adults. The findings will be disseminated through professional bodies, conferences and research papers.
Use of antihistamines before or during pregnancy and risk of early-onset pre-eclampsia in allergic women: a population-based cohort study
Authors: Sande Anne K , Torkildsen Erik Andreas , Sande Ragnar Kvie , Dalen Ingvild , Danielsson Kim Christian , Morken Nils-Halvdan 
Published: October 2022

ObjectiveWe have previously found that allergy is a risk factor for early-onset pre-eclampsia. The aim of this study was to assess the association between pregestational maternal use of antihistamines and early-onset pre-eclampsia.DesignA population-based cohort study.Setting and participantsAll women giving birth in Norway 2004–2016, including 692 487 pregnancies. Data from the Medical Birth Registry of Norway were linked with data from the Norwegian Prescription Database. Prescriptions of antihistamines were divided into three groups: before pregnancy (<6 months), early pregnancy (<20 weeks) and late pregnancy (20–36 weeks). ORs with 95% CIs for pre-eclampsia <34 and <37 weeks by antihistamine use were estimated by logistic regression and stratified on multiple pregnancy and parity. Predicted proportions (%) with 95% CIs were estimated.InterventionsUse of antihistamines in relation to pregnancy in allergic women.Main outcome measuresDevelopment of early-onset pre-eclampsia.Results2997 (0.43%) and 5769 (0.83%) women had pre-eclampsia <34 and <37 weeks, respectively. Use of antihistamines before and in early pregnancy was associated with a risk of developing early-onset pre-eclampsia that was comparable to the background population (OR 1.0, 95% CI 0.8 to 1.2 and OR 0.9, 95% CI 0.7 to 1.1, respectively). Antihistamine use only in late pregnancy was not treated as exposure, but as an indicator of allergy, and was associated with an increased risk of early-onset pre-eclampsia (OR 1.8, 95% CI 1.5 to 2.2). Predicted proportions of pre-eclampsia <34 weeks were significantly lower in women using antihistamines before (0.41%, 95% CI 0.34 to 0.49) and in early pregnancy (0.37%, 95% CI 0.31 to 0.44), compared with women using antihistamines after placentation (0.69%, 95% CI 0.57 to 0.83). Results were similar for pre-eclampsia <37 weeks.ConclusionsAntihistamine use before or during placentation was associated with reduced risk of developing early-onset pre-eclampsia in allergic women compared with women using antihistamines after placentation.
Processed foods purchase profiles in urban India in 2013 and 2016: a cluster and multivariate analysis
Authors: Tak Mehroosh , Law Cherry , Green Rosemary , Shankar Bhavani , Cornelsen Laura 
Published: October 2022

ObjectivesSales of ultraprocessed foods (UPFs) and beverages are rising in low-income and middle-income countries. Such foods are often linked with weight gain, obesity, type 2 diabetes and hypertension—diseases that are on the rise in India. This paper analysed patterns in purchases of processed and UPF by urban Indian households.SettingPanel data from Kantar —Worldpanel Division, India for 2013 and 2016.Participants58 878 urban Indian households.MethodsWe used K-mean partition clustering and multivariate regression to analyse patterns in processed food (PF) and UPF purchase for urban India.ResultsThree-quarters of urban Indian households purchased over ten PF groups. Mean per person annual PF purchase was 150 kg. UPF purchase was low at 6.4 kg in 2016 but had grown by 6% since 2013. Cluster analysis identified three patterns of consumption, characterised by low (54% of the households in 2016), medium (36%) and high (10%) PF purchase quantities. High cluster households purchased over three times as much PFs and UPF as the low cluster households. Notably, salt purchases were persistently high across clusters in both years (>3.3 kg), while sweet snack and ready-to-eat food purchases grew consistently in all clusters between 2013 and 2016. A positive and significant association was found between household purchases of UPF and their socioeconomic status as well as ownership of durables, such as refrigerator, colour television and washing machine (all p<0.001). Spatial characteristics including size of town (p<0.05) in which the household is located were also positively associated with the purchase of UPF.ConclusionResults suggest the need for tailored regional and city level interventions to curb the low but growing purchase of UPF. New data on obesity and rise of non-communicable diseases, the results are concerning given the links between lifestyle changes and the speed of urbanisation in Indian cities.
Assessing the impact of COVID-19 measures on COPD management and patients: a simulation-based decision support tool for COPD services in the UK
Authors: Yakutcan Usame , Hurst John R , Lebcir Reda , Demir Eren 
Published: October 2022

ObjectivesTo develop a computer-based decision support tool (DST) for key decision makers to safely explore the impact on chronic obstructive pulmonary disease (COPD) care of service changes driven by restrictions to prevent the spread of COVID-19.DesignThe DST is powered by discrete event simulation which captures the entire patient pathway. To estimate the number of COPD admissions under different scenario settings, a regression model was developed and embedded into the tool. The tool can generate a wide range of patient-related and service-related outputs. Thus, the likely impact of possible changes (eg, COVID-19 restrictions and pandemic scenarios) on patients with COPD and care can be estimated.SettingCOPD services (including outpatient and inpatient departments) at a major provider in central London.ResultsFour different scenarios (reflecting the UK government’s Plan A, Plan B and Plan C in addition to a benchmark scenario) were run for 1 year. 856, 616 and 484 face-to-face appointments (among 1226 clinic visits) are expected in Plans A, B and C, respectively. Clinic visit quality in Plan A is found to be marginally better than in Plans B and C. Under coronavirus restrictions, lung function tests decreased more than 80% in Plan C as compared with Plan A. Fewer COPD exacerbation-related admissions were seen (284.1 Plan C vs 395.1 in the benchmark) associated with stricter restrictions. Although the results indicate that fewer quality-adjusted life years (in terms of COPD management) would be lost during more severe restrictions, the wider impact on physical and mental health must also be established.ConclusionsThis DST will enable COPD services to examine how the latest developments in care delivery and management might impact their service during and beyond the COVID-19 pandemic, and in the event of future pandemics.
Low-doseinterleukin 2 for the reduction ofvascular inflammation in acute coronarysyndromes (IVORY): protocol and study rationale for a randomised, double-blind, placebo-controlled, phase II clinical trial
Authors: Sriranjan Rouchelle , Zhao Tian Xiao , Tarkin Jason , Hubsch Annette , Helmy Joanna , Vamvaka Evangelia , Jalaludeen Navazh , Bond Simon , Hoole Stephen P , Knott Philip , Buckenham Samantha , Warnes Victoria , Bird Nick , Cheow Heok , Templin Heike , Cacciottolo Paul , Rudd James H F , Mallat Ziad , Cheriyan Joseph 
Published: October 2022

IntroductionInflammation plays a critical role in the pathogenesis of atherosclerosis, the leading cause of ischaemic heart disease (IHD). Studies in preclinical models have demonstrated that an increase in regulatory T cells (Tregs), which have a potent immune modulatory action, led to a regression of atherosclerosis. The Low-dose InterLeukin 2 (IL-2) in patients with stable ischaemic heart disease and Acute Coronary Syndromes (LILACS) study, established the safety of low-dose IL-2 and its biological efficacy in IHD. The IVORY trial is designed to assess the effects of low-dose IL-2 on vascular inflammation in patients with acute coronary syndromes (ACS).Methods and analysisIn this study, we hypothesise that low-dose IL-2 will reduce vascular inflammation in patients presenting with ACS. This is a double-blind, randomised, placebo-controlled, phase II clinical trial. Patients will be recruited across two centres, a district general hospital and a tertiary cardiac centre in Cambridge, UK. Sixty patients with ACS (unstable angina, non-ST elevation myocardial infarction or ST elevation myocardial infarction) with high-sensitivity C reactive protein (hsCRP) levels >2 mg/L will be randomised to receive either 1.5×106 IU of low-dose IL-2 or placebo (1:1). Dosing will commence within 14 days of admission. Dosing will comprise of an induction and a maintenance phase. 2-Deoxy-2-[fluorine-18] fluoro-D-glucose (18F-FDG) positron emission tomography/CT (PET/CT) scans will be performed before and after dosing. The primary endpoint is the change in mean maximum target to background ratios (TBRmax) in the index vessel between baseline and follow-up scans. Changes in circulating T-cell subsets will be measured as secondary endpoints of the study. The safety and tolerability of extended dosing with low-dose IL-2 in patients with ACS will be evaluated throughout the study.Ethics and disseminationThe Health Research Authority and Health and Care Research Wales, UK (19/YH/0171), approved the study. Written informed consent is required to participate in the trial. The results will be reported through peer-reviewed journals and conference presentations.Trial registration numberNCT04241601.