bluuebunny/crossref_metadata_2025_split huggingface dataset:
Migraine and balance impairment: Influence of subdiagnosis, otoneurological function, falls, and psychosocial factors
Authors: Carvalho Gabriela F. , Luedtke Kerstin , Pinheiro Carina F. , Moraes Renato , Lemos Tenysson W. , Carneiro Camila G. , Bigal Marcelo E. , Dach Fabiola , Bevilaqua‐Grossi Debora 
Published: May 2022

AbstractObjectiveTo assess the balance sensory organization among patients with migraine, considering the influence of migraine subdiagnosis, otoneurological function, falls, and psychosocial factors.BackgroundMigraine has been associated with vestibular symptoms and balance dysfunction; however, neither comprehensive balance assessment nor associated factors for greater impairment have been addressed thus far.MethodsPatients from a tertiary headache clinic with a diagnosis of episodic migraine with aura (MWA), without aura (MWoA), and chronic migraine (CM) were included for this cross‐sectional study (30 patients per group). Thirty headache‐free controls (CG) were recruited. Participants underwent a comprehensive evaluation protocol, including the Sensory Organization Test (SOT) and otoneurological examination. Questionnaires about fear of falls, dizziness disability, and kinesiophobia were administered.ResultsAll migraine groups presented lower composite SOT scores than controls (CG: 82.4 [95% confidence interval (CI): 79.5–85.3], MWoA: 76.5 [95% CI: 73.6–79.3], MWA: 66.5 [95% CI: 63.6–69.3], CM: 69.1 [95% CI: 66.3–72.0]; p < 0.0001). Compared to controls and to MWoA, MWA and CM groups exhibited greater vestibular (CG: 75.9 [95% CI: 71.3–80.4], MWoA: 67.3 [95% CI: 62.7–71.8], MWA: 55.7 [95% CI: 51.2–60.3], CM: 58.4 [95% CI: 53.8–63.0]; p < 0.0001) and visual functional impairment (CG: 89.6 [95% CI: 84.2–94.9], MWoA: 83.2 [95% CI: 77.9–88.6], MWA: 68.6 [95% CI: 63.3–74.0], CM: 71.9 [95% CI: 66.5–77.2], p < 0.0001). Fall events during the assessment were documented more often among patients with migraine (CG: 0.0, interquartile range [IQR], 0.0, 0.0); MWoA: 1.0 [IQR: 1.0, 1.0], MWA: 2.0 [IQR: 1.8, 4.3], CM: 1.0 [IQR: 1.0, 2.0]; p = 0.001). The SOT scores correlated with fear of falls (r = −0.44), dizziness disability (r = −0.37), kinesiophobia (r = −0.38), and migraine frequency (r = −0.38). There was no significant influence of the vestibular migraine diagnosis in the study outcomes when used as a covariate in the analysis (composite score [F = 3.33, p = 0.070], visual score [F = 2.11, p = 0.149], vestibular score [F = 1.88, p = 0.172], somatosensory score [F = 0.00, p = 0.993]).ConclusionsAura and greater migraine frequency were related to falls and balance impairment with sensory input manipulation, although no otoneurological alterations were detected. The diagnosis of vestibular migraine does not influence the balance performance. The vestibular/visual systems should be considered in the clinical examination and treatment of patients with migraine.
Prediction of fish quality level with machine learning
Authors: Yavuzer Emre , Köse Memduh 
Published: May 2022

SummaryIn this study, sea bream, sea bass, anchovy and trout were captured and recorded using a digital camera during refrigerated storage for 7 days. In addition, their total viable counts (TVC) were determined on a daily basis. Based on the TVC, each fish was classified as ‘fresh’ when it was <5 log cfu per g, and as ‘not fresh’ when it was >7 log cfu per g. They were uploaded on a web‐based machine learning software called Teachable Machine (TM), which was trained about the pupils and heads of the fish. In addition, images of each species from different angles were uploaded to the software in order to ensure the recognition of fish species by TM. The data of the study indicated that the TM was able to distinguish fish species with high accuracy rates and achieved over 86% success in estimating the freshness of the fish species tested.
Global nursing research activity from 2009 to 2020: A bibliometric analysis
Authors: Wang Cui , Shi Yuexian , Lu Han , Dong Xu , Hou Luoya , Wang Limin , Wan Qiaoqin , Hu Li , Zhang Lei , Dou Dou , Shang Shaomei 
Published: May 2022

AbstractAimBibliometric analysis of the nursing literature can provide insights into the current state and dynamics of the nursing profession. This study aimed to assess global nursing‐related research activity from 2009 to 2020.MethodThe corpus of nursing papers was harvested from the Web of Science Core Collection database. The bibliometric indicators and VOSviewer mapping of the retrieved papers were presented.ResultsThe search found 109,782 papers, and 39.0% of papers reported funded studies. Publication numbers were increasing. The USA was the most prolific country in literature production and international collaboration in nursing studies. International cooperation in nursing research was dominated by developed regions. Among the 20 most cited articles, 75% were published in first quartile journals, and review papers received a higher number of citations than original research articles. Author keyword analysis identified ‘quality of life’, ‘mental health’, ‘nursing students' education’ and ‘adolescent’ as common nursing focus topics.ConclusionsThe publication trend of nursing papers was positive. However, several problems were associated with nursing research activity, including low research funding, regionally centred research activity and inactivity of developing regions in terms of international collaborations, which need to be addressed by policy makers, nursing managers and scholars.
Élaboration d'un indice composite de qualité de l'emploi des travailleurs et travailleuses LGBTQ+ du Québec (Canada)
Authors: BAIOCCO Michele , BLAIS Martin , SAMOILENKO Mariia , CHAMBERLAND Line , CÔTÉ Isabel 
Published: May 2022

RésuméL'hétérosexisme et le cisgenrisme peuvent conduire à des expériences d'exclusion sociale vécues au travail, qui nuisent au bien‐être des personnes LGBTQ+. Pour mesurer cette réalité, les auteurs construisent un indice de qualité de l'emploi spécifique, en s'appuyant sur des données issues d'un échantillon de 1 761 travailleurs et travailleuses LGBTQ+ du Québec, recrutés dans le cadre de l'enquête SAVIE‐LGBTQ (2019–2020). Cet indice, créé au moyen de scores factoriels, comprend 16 indicateurs et 5 dimensions. Il possède une cohérence interne acceptable et est associé modérément à la satisfaction au travail des personnes LGBTQ+. L'indice révèle des différences attendues entre les groupes, ce qui soutient sa validité conceptuelle.
Photosynthesis and salt cations adsorption response of spring maize (Zea mays L.) to salinity stress caused by different drip irrigation regimes in an arid saline area, Northwest China
Authors: Cheng Yu , Zhang Tibin , Qiao Ruonan , Yan Sihui , Luo Min , Wang Chun , Zhang Tonggang , Dong Qin'ge , Feng Hao 
Published: May 2022

AbstractSalinity is one of the most decisive environmental factors limiting crop productivity, especially in arid and semi‐arid regions. The objective of this study was to evaluate the growth depression of spring maize (Zea mays L.) due to salinity stress caused by different drip irrigation regimes in an arid saline area. A two‐year field experiment was conducted in the Hetao Irrigation District, northwest China in 2019 and 2020. The study soil was moderately saline with ECe (electrical conductivity of saturated soil extract) of 8.04 dS m−1. Three threshold values of soil matric potential (SMP), −10, −30, and −50 kPa, were used to trigger a 10–20 mm drip irrigation of spring maize. Nine plots were arranged in a randomized block design (with triplication for each SMP level). Results showed that the lower soil salinity caused by higher SMP levels significantly increased crop photosynthetic capacity and reduced salt cations (K+, Na+, Ca2+, Mg2+) concentrations in plant organs, thereby increasing aboveground biomass and grain yields. Gas exchange parameter values first increased and then decreased in the R1–R5 stage (76–115 DAP) except for net photosynthetic rate (Pn) of −10 kPa treatment. Four salt cations in the aboveground parts were mainly distributed in stems and leaves, followed by grains. However, there was no significant difference in aboveground cationic accumulation among treatments. Correlation analysis indicated that gas exchange parameter values were negatively correlated with concentrations of K+, Na+, Ca2+, and Mg2+ in aboveground plant organs at harvest, indicating that Pn could quantitatively reflect the salt ionic toxicity in crops to a large extent. Considering photosynthesis, salt cations absorption, and water use efficiency, an SMP threshold of −30 kPa is recommended for drip irrigation of maize in this arid saline condition. These findings can provide a theoretical basis and technical reference for the promotion of mulched drip irrigation under the arid saline condition.
A commercial SnF2 toothpaste formulation reduces simulated human plaque biofilm in a dynamic typodont model
Authors: Khosravi Yalda , Palmer Sara , Daep Carlo A. , Sambanthamoorthy Karthik , Kumar Purnima , Dusane Devendra H. , Stoodley Paul 
Published: May 2022

Abstract

Aims
We present a dynamic typodont biofilm model (DTBM) incorporating (1) human dentition anatomy, (2) fluid flow over intermittently fluid bathed tooth surfaces and (3) an oxic headspace to allow aerobic and anaerobic niches to develop naturally, as a screening tool to assess the effect of stannous fluoride (SnF2) toothpaste against a simulated human plaque biofilm (SPB).

Methods and results
First, hydroxyapatite (HA) coupons were inoculated with human saliva/plaque and cultured at 37°C under air. Selected species representative of common commensal and anaerobic pathogens were quantified for relative abundance changes over 4 days by PCR densitometry to confirm the culture conditions allowed the proliferation of these species. A continuous culture DTBM reactor on a rocker table was inoculated with saliva/plaque and incubated at 37°C for 24 h. Tooth shear stress was estimated by particle tracking. A SnF2 toothpaste solution, or a sham rise was administered twice daily for 3 days to mimic routine oral hygiene. SPB biomass was assessed by total bacterial DNA and methylene blue (MB) staining. Early colonizer aerobes and late colonizer anaerobes species were detected in the HA and DTBM, and the trends in changing abundance were consistent with those seen clinically.

Conclusions
Treatment with the SnF2 solution showed significant reductions of 53.05% and 54.4% in the SPB by MB staining and DNA, respectively. Significance and impact of study: The model has potential for assessing dentition anatomy and fluid flow on the efficacy of antimicrobial efficacy against localized SPB and may be amenable to the plaque index clinical evaluation.
The impact of an online gamified approach embedded with self‐regulated learning support on students' reading performance and intrinsic motivation: A randomized controlled trial
Authors: Qiao Shen , Chu Samuel Kai Wah , Shen Xiaoai , Yeung Susanna Siu‐sze 
Published: May 2022

AbstractBackgroundMorphological awareness (MA) is the awareness and ability to manipulate morphemes, the smallest units of meaning in a language. It is identified as a strong cognitive precursor of word reading and reading comprehension. The current MA instructions are limited to classroom settings and delivered by teachers or experimenters. Few studies have included technology and its novel features to deliver MA instructions.ObjectivesThis study proposes a gamified learning approach embedded with self‐regulated learning support for MA learning and examines its effects on improving English reading performance and intrinsic motivation among junior secondary grade students who learn English as a foreign language.MethodsThis study adopted a randomized controlled trial design. Participants (N = 104) were randomly assigned into one of three conditions: self‐regulated gamified programme, gamified programme, or non‐gamified programme. Students received 16 sessions of instructions (30 min/session) and were evaluated on reading abilities (i.e., MA, word reading and reading comprehension) and intrinsic motivation before and after the programme implementation.Results and conclusionsResults from repeated measures ANOVA and follow‐up ANCOVA showed that while the two gamified groups demonstrated greater improvement in MA (i.e., near transfer effect) and intrinsic motivation than non‐gamified group, only the self‐regulated gamified group showed more gains in multisyllabic word reading (i.e., far transfer effect) than non‐gamified group. There was no significant time X group interaction effect on reading comprehension.ImplicationsTaken together, this research suggests gamification leads to better morphology learning and increases students' intrinsic motivation. The incorporation of self‐regulated learning in gamification is recommended to achieve the far transfer effect on multisyllabic word reading.
Enhanced conditions for anthocyanin extraction from blackberry pomace under ultrasound irradiation
Authors: Santos Suelen Siqueira dos , Magalhães Flávia de Santana , Paraíso Carolina Moser , Ogawa Camilla Yara Langer , Sato Francielle , Santos Junior Oscar de Oliveira , Visentainer Jesuí Vergílio , Madrona Grasiele Scaramal , Reis Miria Hespanhol Miranda 
Published: May 2022

AbstractThe recovery of bioactive compounds from agro‐industrial residues with green solvents in ultrasound‐assisted extraction (UAE) processes represents an interesting alternative from environmental and economical perspectives. Here we investigated optimal conditions to improve the extraction of anthocyanins from blackberry pomace. The experimental data were fitted to the second‐order polynomial model to obtain the regression coefficients, and three‐dimensional (3‐D) response surface plots were considered to represent the relationships between each variable on the response of total monomeric anthocyanin (TMA) content. The ultrasound‐assisted process at an ultrasound amplitude of 40% for 10 min and a concentration of 25 mg/L resulted in the maximum TMA concentration of 1.39 ± 0.02 mgCy3GlE/g. At these extraction conditions, the extract presented total polyphenol and flavonoid contents of 44.12 ± 0.17 mgGAE/g and 63.25 ± 0.53 mgQE/g, respectively. A total of 31 individual compounds, including anthocyanins, flavonols, and phenolic acids, were identified in the extract. Concentrations of cyanidin‐3‐glucoside and caffeic, gallic, and ellagic acids were 2.38 ± 0.09, 0.47 ± 0.01, 0.55 ± 0.01, and 0.48 ± 0.01 mg/g, respectively. Compared to the conventional extraction, the UAE represented an increase of 20.87% in total anthocyanins. Thus, the UAE at suitable conditions is suggested to recover bioactive compounds from blackberry pomace.Practical ApplicationsThe use of blackberry pomace to extract bioactive compounds is promising because it uses a by‐product from the fruit processing industry. This study presents an innovative proposal of optimal process conditions to recover anthocyanins from blackberry pomace under ultrasound irradiation. The use of green solvents, as water, in ultrasound‐assisted extraction (UAE) processes, represents an interesting alternative from environmental and economical perspectives, UAE process is a favorable, fast, efficient, and environmentally friendly method. The obtained blackberry pomace powder is an interesting ingredient to food and pharmaceutical industries, mainly due to the elevated concentration of added‐value compounds. Besides the high amount of anthocyanins content, which could be used as a dye and as antioxidant compounds in several types of food.
REVEILLE 7 inhibits the expression of the circadian clock gene EARLY FLOWERING 4 to fine‐tune hypocotyl growth in response to warm temperatures
Authors: Tian Ying‐Ying , Li Wei , Wang Mei‐Jing , Li Jin‐Yu , Davis Seth Jon , Liu Jian‐Xiang 
Published: May 2022

ABSTRACTThe circadian clock maintains the daily rhythms of plant growth and anticipates predictable ambient temperature cycles. The evening complex (EC), comprising EARLY FLOWERING 3 (ELF3), ELF4, and LUX ARRHYTHMO, plays an essential role in suppressing thermoresponsive hypocotyl growth by negatively regulating PHYTOCHROME INTERACTING FACTOR 4 (PIF4) activity and its downstream targets in Arabidopsis thaliana. However, how EC activity is attenuated by warm temperatures remains unclear. Here, we demonstrate that warm temperature‐induced REVEILLE 7 (RVE7) fine‐tunes thermoresponsive growth in Arabidopsis by repressing ELF4 expression. RVE7 transcript and RVE7 protein levels increased in response to warm temperatures. Under warm temperature conditions, an rve7 loss‐of‐function mutant had shorter hypocotyls, while overexpressing RVE7 promoted hypocotyl elongation. PIF4 accumulation and downstream transcriptional effects were reduced in the rve7 mutant but enhanced in RVE7 overexpression plants under warm conditions. RVE7 associates with the Evening Element in the ELF4 promoter and directly represses its transcription. ELF4 is epistatic to RVE7, and overexpressing ELF4 suppressed the phenotype of the RVE7 overexpression line under warm temperature conditions. Together, our results identify RVE7 as an important regulator of thermoresponsive growth that functions (in part) by controlling ELF4 transcription, highlighting the importance of ELF4 for thermomorphogenesis in plants.
Ultrasonographic observation of the masseter muscle after injection of different botulinum toxin type A
Authors: Li Zhujun , Li Zirong , Li Yunzhu , Dong Ruijia , Chen Cheng , Huang Jiuzuo , Xia Zenan , Yu Nanze , Long Xiao 
Published: May 2022

AbstractBackgroundBotulinum toxin type A (BoNT‐A) injection is a popular cosmetic procedure in East Asian countries, and there are multiple types of toxins on the market. Whether different toxin types induce different changes in the masseter has not been studied.ObjectiveWe aimed to investigate and compare the changes induced by injection of different types of BoNT‐A in the masseter.MethodsUpon retrospective review of clinical records and routine ultrasound examination results of patients who underwent BoNT‐A injection, four groups were set for comparison: unapproved toxin, OnabotulinumtoxinA, LanbotulinumtoxinA, and non‐injected. Clinical records and ultrasound images were collected. Ultrasound images were taken in both horizontal and coronal planes. Elasticity of the masseter muscle was also investigated by measuring the surface wave speed.ResultsA total of 24 patients were included (six patients per group). All patients were young females. For the non‐injected group, the deep inferior tendon was clear and the muscle bundles were arranged, with little fibrous content. Patients who received unapproved toxin injection showed highly disarranged muscle and fiber bundles, with much fiber content present. The changes in OnabotulinumtoxinA and LanbotulinumtoxinA groups were in between those in the non‐injected and unapproved toxin groups. Muscle rigidity was the highest in the unapproved toxin group, and generally higher in injected groups compared with the non‐injected group.ConclusionDifferent types of BoNT‐A may induce different changes in the masseter.
Diet and stomach characteristics of feral piglets (Sus scrofa): Implications for farmed piglets
Authors: van Hees Hubèrt M. J. , Ballari Sebastián A. , Dieste‐Pérez Lucía , Carpinetti Bruno N. , Janssens Geert P. J. 
Published: May 2022

AbstractEvaluation of the diet of the pig (Sus scrofa) in natural settings may provide new views on diet optimization for growth and development of commercially raised piglets under farm conditions. A field study was conducted to gain insight in the diet and stomach characteristics of feral piglets. Forty animals (body weight: 4.6 ± 1.37 kg) were collected from the Bahía Samborombón (Buenos Aires, Argentina). Stomachs were weighed after storage in formalin and the particle size distribution of their contents was determined by wet sieving. Diet items present in their stomachs were classified and their proportional weight and relative abundance was calculated. Based on their dentition, 5, 16 and 19 piglets were approximately 1, 3–6 and 6–16 weeks of age respectively. Vegetable matter (mainly ‘leaves and stems’) was predominantly present in 39 animals. It represented on average 83 ± 36.4% of total stomach contents by weight. The stomachs of 12 piglets contained curd and represented on average 16 ± 35.1% by weight. Other diet items were less abundant or absent. The proportion of stomach particles retained were 24%, 13%, 22%, 13% and 28% for sieves with mesh sizes of 2000, 1000, 420, 210 and <210 µm respectively. For comparison, we used data of farmed piglets of similar age and fed a nutrient‐dense, finely ground diet. Feral piglets' relative empty stomach weights increased with age (p < 0.050), whereas this was not the case for farmed piglets. Relative stomach contents weight increased significantly with age only for farmed piglets (p < 0.050). We infer from our data that feral suckling piglets consumed a variety of non‐milk items, mainly consisting of vegetable material with a coarse particle size from their first week in life onwards. Their diet is associated with an enhanced stomach development compared to those of farmed piglets.
Native and alien grassland diversity respond differently to environmental and anthropogenic drivers across spatial scales
Authors: Bergamin Rodrigo Scarton , Ascensão Fernando , Capinha César , Bastazini Vinicius Augusto Galvão , Andrade Bianca Ott , Boldrini Ilsi Iob , Lezama Felipe , Altesor Alice , Perelman Susana , Overbeck Gerhard Ernst 
Published: May 2022

AbstractAimsTo identify environmental and anthropogenic drivers of alpha‐ and beta‐diversity for native and alien plant species.LocationRío de la Plata grasslands, South America (Argentina, Brazil and Uruguay; 27.3–39.1°S, 50.1–66.5°W).MethodsWe assembled a data set of 597 vegetation plots distributed across the Río de la Plata grasslands. To assess the drivers of native and alien alpha‐diversity (species richness), we performed a generalized least‐squares regression using environmental and anthropogenic predictors. We evaluated differences in beta‐diversity using Simpson's pairwise dissimilarity between pairs of plots and used multiple regression on distance matrixes to investigate environmental and anthropogenic drivers on compositional dissimilarity for both native and alien plant species.ResultsNative species richness was higher in sites with less demanding environmental conditions, such as lower precipitation seasonality and soils with higher cation exchange capacity. Numbers of alien species were positively related to soil pH, cropland density and road density and negatively to precipitation seasonality, mean temperatures and soil cation exchange capacity. The compositional dissimilarity was similar for native and alien species assemblages (mean ± SD: 0.64 ± 0.16 and 0.64 ± 0.35 respectively). Areas having similar climates and being geographically close shared more taxonomically similar assemblages, for both native and alien assemblages, while soil had disparate effects. Compositional dissimilarity of alien plants decreased with increasing road density.ConclusionsOur results highlight a grassland ecosystem where native species richness is still shaped only by environmental factors, but both sets of factors influence its composition. On the other hand, alien plants carry a strong signal of both environmental and human factors. As time progresses the number of alien species tend to increase, eroding the patterns of native biodiversity. To avoid this, efforts should be made to reduce road encroachment and the conversion of natural grasslands into croplands.