bluuebunny/crossref_metadata_2025_split huggingface dataset:
The calibration laboratories for the measurement of radon and short-lived radon decay products at the Federal Office for Radiation Protection (BfS)
Authors: Hamel P. , Schmidt V. 
Published: March 2022

Abstract
In order to guarantee a high level of accuracy in all areas concerned with radon and radon decay products measurement the BfS has established a quality assurance management system. A set of calibration chambers and containers was installed in the laboratories which were subsequently accredited as a German Calibration Service (DKD) Calibration Laboratory for the units of radon and the potential alpha energy concentration of its short-lived decay products. It is traced back to the national standard established at the Physikalisch-Technische Bundesanstalt (PTB), which is at the same time the national institute for science and technology, and the highest technical authority for metrology in Germany. The equipment makes possible scientific investigations as well as calibrations for the measuring quantity “concentration of Rn-222 in air” in the range between 50 Bq/m3 and 100 kBq/m3 and also for the measuring quantity “potential alpha-energy concentration” (PAEC) in the range between 2 MeV/cm3 (3.2 E-7 J/m3) and 4000 MeV/cm31 (*6 .4 E-4 J/m3).
Ageing management review for reactor license renewal
Authors: Lee S. , Kuo P. T. 
Published: March 2022

Abstract
The Nuclear Regulatory Commission (NRC) issues licenses for commercial power reactors to operate for up to 40 years and allows these licenses to be renewed for additional periods of 20 years. In 1995 the Commission issued Part 54 of Title 10 of the Code of Federal Regulations (10 CFR Part 54) specifying the regulatory requirements for license renewal. The license renewal rule focuses on managing the adverse effects of ageing of plant structures and components. The NRC staff has developed license renewal rule implementation guidance documents. The NRC staff uses a systematic approach in evaluating the adequacies of ageing management programs. The NRC has approved several license renewal applications to date and will likely be asked to approve dozens more over the next 10 to 15 years.
Ageing management in German nuclear power stations from an expert’s point of view
Authors: Reßing W. , Dittmar S. 
Published: March 2022

Abstract
This paper gives a general view of the present state of ageing management in the Federal Republic of Germany, including the requirements set out in the set of rules and its handling within the plants. Moreover, it describes the requirements on ageing management and/or ageing monitoring in the area of materials ageing from the point of view of the expert and sets out in what way ageing processes have already manifested themselves in the area of mechanical and electrical engineering systems. And finally, it gives an outlook on current projects that, among other things, aim at making transparent the application of the methods of ageing management according to uniform requirements and rules and thus with a considerable depth.
Ageing management within British Energy in support of safe, reliable operation and lifetime extension objectives
Authors: Banks P J. 
Published: March 2022

Abstract
British Energy has established a comprehensive suite of ageing/obsolescence asset management programmes. Through these programmes, the company has developed a thorough understanding of all the potentially significant degradation mechanisms which could affect the systems structures and components (SSCs) which are essential to the safe, reliable operation of their NPPs. The results from these ageing management programmes underwrite the existing design basis safety case, provide trending information for Safety System Reviews (SSRs) and Periodic Safety Reviews (PSRs) and provide data in support of extending the operating lifetimes of the NPPs. This paper describes te UK regulatory framework with respect to ageing management, British Energy’s overall approach to ageing management, The various ageing/obsolescence management programmes established by BEG, including examples of potentially significant ageing issues which have been successfully addressed by these programmes and the manner in which the results from the programmes are used in support of continued operation, SSRs, PSRs, lifetime extension and general performance enhancement.
Optimal diagnosis of the skin cancer using a hybrid deep neural network and grasshopper optimization algorithm
Authors: Li Gengluo , Jimenez Giorgos 
Published: March 2022

Abstract
When skin cells divide abnormally, it can cause a tumor or abnormal lymph fluid or blood. The masses appear benign and malignant, with the benign being limited to one area and not spreading, but some can spread throughout the body through the body’s lymphatic system. Skin cancer is easier to diagnose than other cancers because its symptoms can be seen with the naked eye. This makes us to provide an artificial intelligence-based methodology to diagnose this cancer with higher accuracy. This article proposes a new non-destructive testing method based on the AlexNet and Extreme Learning Machine network to provide better results of the diagnosis. The method is then optimized based on a new improved version of the Grasshopper optimization algorithm (GOA). Simulation of the proposed method is then compared with some different state-of-the-art methods and the results showed that the proposed method with 98% accuracy and 93% sensitivity has the highest efficiency.
Comparison of LPBF-manufactured and rolled tensile test samples made of 17-4PH
Authors: Roj Robin , Blondrath Aileen , Serleti Francesco , Holm Christopher , Theiß Ralf , Dültgen Peter 
Published: March 2022

Abstract
In recent years additive manufacturing techniques for metals became more and more enhanced and a great variety of processable materials are available. Nevertheless, the quality of 3D-printed components is often not obvious, and, depending on the material, it is not known whether they are as resilient as conventionally manufactured parts. In this paper rolled tensile test samples made of 17-4PH are compared with additively manufactured ones. For this purpose, they were printed by Laser Powder Bed Fusion in three different orientations, 0°, 45°, and 90°, and subsequently tensile tested. The presented results contain mesoscopic images of the fracture surfaces, as well as an analysis of the metallographic microstructure. Further details about the measured hardness, the phase diagrams as well as an optimized heat treatment are described in detail. It is shown that specifically the heat treated specimens with a 45° orientation reaches the highest ultimate tensile stress, but possess a low ductility in comparison to the conventional components.
Update of randomized controlled trials evaluating cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) in prevention and therapy of peritoneal metastasis: a systematic review
Authors: Noiret Barbara , Piessen Guillaume , Eveno Clarisse 
Published: March 2022

Abstract

Background
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) is associated with favorable short- and long-term oncological outcomes in highly selected patients with peritoneal metastasis (PM). The aim of our review was to review published, recruiting or ongoing randomized controlled trials (RCTs) evaluating CRS and HIPEC vs. other strategies (systemic chemotherapy or CRS alone) and to update the studies recently described in 2016.

Content
Systematic review according to PRISMA guidelines. Searches for published and ongoing trials were based, respectively, on PubMed and international clinical databases since 2016.

Summary
46 trials randomized 9,063 patients: 13 in colorectal cancer (3 in therapeutic strategy and 10 in prophylactic strategy), 16 in gastric cancer (4 in therapeutic strategy and 12 in prophylactic strategy) and 17 in ovarian cancer (12 in front-line therapy and 5 in recurrence settings).

Outlook
In contrast to many recruiting studies, few published studies analyzed the potential advantage of CRS and HIPEC in therapeutic and prophylactic treatment of PM. The potential effect of this combined treatment has been proven in ovarian cancer in interval surgery, but remains still debated in other situations. Promising trials are currently recruiting to provide further evidence of the effectiveness of CRS and HIPEC.
Conversion of Municipal Solid Waste Incineration Bottom Ash in Asphalt Pavements
Authors: Yan Kezhen , Li Lanlan , Long Zhengwu , Xiao Leling , Liu Kai , Zhou Wujun , You Lingyun , Ou Jianliang , Wu Shenghua 
Published: March 2022

Abstract
Municipal waste incineration (MSWI) is a widely used method in solid waste treatment that can reduce the generation of landfill waste. Meanwhile, MSWI-bottom ash (BA) can be employed as a substitute for aggregates in asphalt mixtures. This study aims to assess the feasibility and influence of MSWI-BA substitution for natural limestone aggregates in asphalt mixtures to reduce garbage accumulation and save natural resources. Through conventional methods, the energy dispersive X-ray spectrometer, and scanning electron microscope experiments, the physical and chemical features of MSWI-BA and natural limestone aggregate were analyzed. A Marshall mix design determined the optimum asphalt content of asphalt mixtures with various MSWI-BA contents. The road performances of asphalt mixtures with different MSWI-BA contents were studied using rutting, low-temperature splitting, freeze–thaw splitting, and Marshall immersion tests. The experiment results show that adding MSWI-BA to asphalt mixtures would decrease water stability. High-temperature stability is excellent when adding 10 % MSWI-BA, and low-temperature crack resistance is best at 20 % MSWI-BA content. MSWI-BA could be recycled in the asphalt pavement, and 10 % is recommended.
Developing Prediction Model on Workability Parameters of Ultrasonicated Nano Silica (n-SiO2) and Fly Ash Added Cement-Based Grouts by Using Artificial Neural Networks
Authors: Çolak Andaç Batur , Yıldız Oğuzhan , Çelik Fatih , Bozkır Samet Mufit 
Published: March 2022

Abstract
In this experimental study, the workability and bleeding properties of cement-based grout mixes combined with fly ash (FA) and nano silica (n-SiO2) as colloidal nanopowder were investigated, and some prediction models were developed with the artificial neural network. The Marsh cone flow time, mini slump spreading diameter, and plate cohesion meter values of samples prepared in different concentrations have been measured and analyzed experimentally to investigate the workability properties. Moreover, bleeding tests were carried out on the grout mixtures prepared within the scope of this experimental study. Test results showed that the usage of FA as a mineral additive in the grout samples positively contributed to an increase on the fluidity of the grout samples as expected. Although the increase in n-SiO2 content in the grout mixes resulted in an increase in the Marsh cone flow time of the grout mixes, it resulted in a decrease in the mini slump spreading diameter of the samples. The increase in the plate cohesion values of the grout mixtures was also observed in the n-SiO2 added grout mixtures. At the same time, the bleeding values of the grout mixes with and without mineral additives of 0.9 % or more with n-SiO2 additives remained above 900 ml (below 10 % bleeding rate). The artificial neural network model can predict the workability properties of cement-based grouts containing n-SiO2 nanoparticle-doped FA with high accuracy.
The Other, the New, and the Old. Three Images of Leith in Irvine Welsh’s Porno
Authors: Zibalas Deividas 
Published: March 2022

The present paper focuses on Irvine Welsh’s novel Porno (2002), the sequel to Trainspotting (1993). Most of the events of the novel take place in Edinburgh, and the changing face of Leith, a working-class neighbourhood, becomes the central axis in the story. By drawing on Edward Relph (1976) and Harold M. Proshansky et al. (2014 [1983]), this reading of Welsh’s novel attempts to show how the main characters self-consciously reflect on the neighbourhood’s changing identity, as well as the implications these changes have for their own sense of self. Multiperspectivity becomes the mode Welsh employs to project a nuanced image of Leith, as seen from the subjective perspectives of five internal narrators. What becomes of interest in the novel is not the identity of Leith per se, but the different images of Leith that emerge through the way the narrators identify with the neighbourhood. Specifically, three images of Leith are distinguished and explored in the paper.
Perceived Career Barriers Scale: Validation for a Lithuanian Sample
Authors: Sadauskaitė Raimonda , Kairys Antanas 
Published: March 2022

Career is undoubtedly an essential part of people’s lives. Unfortunately, career development does not necessarily go smoothly because various circumstances, such as career barriers, might constrain career development. Therefore, it is important to have valid and reliable instruments that help evaluate and understand this phenomenon. The current study aimed to test the validity of the Lithuanian version of the Perceived career barriers scale. The sample included 382 participants aged from 18 to 63 years (M = 37.5 years, SD = 13.6). Two hundred twenty-six of the participants were females, 155 were males, and one did not disclose their gender. The Perceived Career Barriers Scale was translated from the German language using the back translation technique. Its construct validity was confirmed by confirmatory factor analysis. Results also showed that the scale is reliable. Convergent validity of the scale was also confirmed – perceived career barriers correlated with career self-efficacy, Past Negative time perspective, Present Fatalistic time perspective, and Future Negative time perspective. The Perceived Career Barriers Scale may be used for further research, although it is recommended to conduct a more comprehensive validity evaluation.
The well-being of older age Lithuanians: Policy implications
Authors: Kairys Antanas , Zamalijeva Olga , Bagdonas Albinas , Eimontas Jonas , Pakalniškienė Vilmantė , Sadauskaitė Raimonda 
Published: March 2022

Many countries of the world consider the well-being of citizens to be one of their most important goals. Nowadays there is a growing concern about the well-being of older people. Considering the aging population, there is a call for social policies aimed at strengthening the well-being of older people. Therefore, recommendations were prepared for policymakers on possible ways to strengthen the well-being of the older age Lithuanian population. The recommendations are based on data from the 7th wave of the Survey of Health, Aging, and Retirement in Europe (SHARE). There were 2014 persons aged 50 and older interviewed in Lithuania in the 7th wave of the SHARE survey. Data on various aspects of well-being, health, work and economic situation, childhood circumstances, experiences of discrimination were analyzed. Based on different aspects of well-being it was found, that respondents can be grouped into high, low, and medium well-being clusters, moreover the analysis showed that the Lithuanian population has relatively low well-being compared to other countries. Recommendations were formulated covering possible measures for chronic diseases, co-morbid mental health disorders, work, economic situation, childhood environment, and personal life history. The recommendations are addressed to health, social and employment, education, and science policymakers.
Tatars in the History and Culture of Lithuania from the 14th to the 21st Centuries: the Latest Researches
Authors: Miškinienė Galina 
Published: March 2022

The Parliament (Seimas) of the Republic of Lithuania the year 2021 declared as the year of the history and culture of Lithuanian Tatars. Lithuanian Tatars have left a bright footprint in the history of Lithuania, and they are a part of its history as well. The descendants of the Tatars of the Grand Duchy of Lithuania live in three countries: Lithuania, Belarus and Poland, and their compatriots – in Crimea, Tatarstan and Turkey.
Among the events of the commemorating programme of the Year of the History and Culture of Lithuanian Tatars, which was approved by the Government of the Republic of Lithuania, is the international scientific conference “Tatars in the History and Culture of Lithuania from the 14th to the 21st Centuries: the latest researches”, which took place on the 9th–11th of September 2021 at the Faculty of Philology of Vilnius University live and remotely. International conferences, dedicated to the research of Lithuanian Tatar history, culture, writing and religion, are being organized periodically in Lithuania. As well as at the other conferences, the manuscript heritage (kitabistics) of Lithuanian Tatars – the field of researches, which is being the mostly developed – was discussed at this conference too.
Improving Vancomycin Stewardship in Critically Ill Children
Authors: Chiotos Kathleen , Fitzgerald Julie C. , Hayes Molly , Dashefsky Hannah , Metjian Talene A. , Woods-Hill Charlotte , Biedron Lauren , Stinson Hannah , Ku Brandon C. , Robbins Tighe Sheila , Weiss Scott L. , Balamuth Fran , Schriver Emily , Gerber Jeffrey S. 
Published: March 2022

BACKGROUND AND OBJECTIVES
Inappropriate vancomycin use is common in children’s hospitals. We report a quality improvement (QI) intervention to reduce vancomycin use in our tertiary care PICU.

METHODS
We retrospectively quantified the prevalence of infections caused by organisms requiring vancomycin therapy, including methicillin-resistant Staphylococcus aureus (MRSA), among patients with suspected bacterial infections. Guided by these data, we performed 3 QI interventions over a 3-year period, including (1) stakeholder education, (2) generation of a consensus-based guideline for empiric vancomycin use, and (3) implementation of this guideline through clinical decision support. Vancomycin use in days of therapy (DOT) per 1000 patient days was measured by using statistical process control charts. Balancing measures included frequency of bacteremia due to an organism requiring vancomycin not covered with empiric therapy, 30-day mortality, and cardiovascular, respiratory, and renal organ dysfunction.

RESULTS
Among 1276 episodes of suspected bacterial infection, a total of 19 cases of bacteremia (1.5%) due to organisms requiring vancomycin therapy were identified, including 6 MRSA bacteremias (0.5%). During the 3-year QI project, overall vancomycin DOT per 1000 patient days in the PICU decreased from a baseline mean of 182 DOT per 1000 patient days to 109 DOT per 1000 patient days (a 40% reduction). All balancing measures were unchanged, and all cases of MRSA bacteremia were treated empirically with vancomycin.

CONCLUSION
Our interventions reduced overall vancomycin use in the PICU without evidence of harm. Provider education and consensus building surrounding indications for empiric vancomycin use were key strategies.
Predictive model of small choroidal melanoma progression after eye-saving treatment based on clinical, morphometric and immunological parameters
Authors: Myakoshina E. B. , Kulikova I. G. , Balatskaya N. V. , Katargina L. A. , Saakyan S. V. 
Published: March 2022

Choroidal melanoma is a malignant tumor characterized by early metastasis and poor vital prognosis. Prognostic indexes for the tumor development are of importance, depending on various factors and making it possible to optimize therapeutic measures. Usage of present models for prediction of the uveal melanoma course enables optimal management of the patients with a malignant tumor upon primary admission, and to perform maximally efficient counseling. So far, however, a complex of clinical, morphometric and immunological indexes predictive for unfavorable course of initial choroidal melanoma following the eye-saving treatment remains not fully determined. Our purpose was to create a prognostic model for initial choroidal melanoma after eye-saving treatment, basing on clinical, morphometric and immunological parameters.We have performed examination and treatment of 31 patients with small choroidal melanoma (53.7 to 12.2 years old). To perform the analysis, we used clinical data (age, decreased vision, tumor localization, degree of pigmentation, presence of hemorrhages, orange pigmentation), morphometric indexes (intra- and subretinal exudate and disorganization of pigment of the retinal epithelium) and immunological parameters (serum levels of pro-inflammatory, pro-angiogenic, proliferative, metastasis-causing cytokines). Selection of variables for this model was based on assessment of significant differences between the groups with chorio-retinal scar (n = 14) and residual tumor and/or continued tumor growth (n = 17).Multivariate analysis with conditional exclusion of variables revealed prognostic significance with four markers: morphometric, i.e., disorganization of the pigment in retinal pigment epithelium – Z1 (rs = 0.455); immunological, increased blood serum concentration of hepatocyte growth factor (HGF) – Z2 (rs = 0.377); level of pro-inflammatory chemokine RANTES – Z3 (rs = 0.362), content of transforming growth factor (TGF-2â) – Z4 (rs = 0.431). A formula was calculated where P (z) is the value of the logistic function; Z, linear combination of symptoms; bo , intercept (free term), bi – regression coefficients for parameters Zi.P (z) = 1 : 1 + e – b0– b1z1– b2z2– b3z3– b4z4The logistic function increases monotonically and takes the values from 0 to 1 for any b and Z values [P∈ (0;1)]. If P (Z) is under the cutoff value, chorioretinal scar prognosis is predicted, at the higher values, a residual tumor or continued growth is expected. In ROC analysis, the area under the curve with this model was 0.891±0.11, thus providing good predictive quality.Usage of the predictive model is a possible solution for planning and correcting treatment strategy in the patients with small choroidal melanoma, in order to minimize complications and errors, and to ensure control of treatment.