bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of an enzyme immunoassay for measurement of fecal dehydroepiandrosterone sulfate in gibbons and siamangs
Authors: Takeshita Rafaela S. C. 
Published: March 2022

AbstractMonitoring wildlife stress levels is essential to ensure their quality of life in captivity or in the wild. One promising method to assess the stress response is the comeasurement of glucocorticoids (GC) and dehydroepiandrosterone sulfate (DHEAS), adrenal hormones involved in the modulation of the stress response. Although noninvasive methods to measure GCs have been validated in several species, only a few studies have validated DHEAS assays. The aims of this study were (1) to describe an enzyme immunoassay (EIA) to measure DHEAS levels, (2) to validate this assay for fecal samples in gibbons and siamangs, and (3) to test hormonal stability after one freeze‐thaw cycle and over time at two freezer temperatures (−20°C and −80°C). Subjects included 32 gibbons and siamangs from U.S. zoological parks. The EIA was validated analytically by parallelism and accuracy tests, and biologically by confirming a DHEAS response 1–2 days after a stressful event (accident, vaccination, or transportation) in three individuals. In addition, fecal DHEAS levels in a pregnant female were above nonpregnant/nonlactating levels and declined progressively the following parturition. The hormonal stability experiments revealed no significant changes in fecal DHEAS levels after one freeze‐thaw cycle. Hormonal levels in fecal extracts were stable for 2 months, regardless of the storage temperature, with no significant differences between −20°C and −80°C conditions. The EIA described has high sensitivity and it is suitable for fecal DHEAS measurement in gibbons and siamangs, with a potential to be applied to other species.
Gendered Labour
Authors: Christou Anastasia , Kofman Eleonore 
Published: March 2022

AbstractAs we saw in Chap. 10.1007/978-3-030-91971-9_1, the gendered transfer of labour globally and within Europe has been the focus of attention and the core of the discourse concerning the feminization of migration. Whilst gendered labour migrations are not new, their composition, extent, and how we analyse them, theoretically and methodologically, have evolved. As data show, migrants and especially females, are heavily concentrated within certain sectors producing not just a migrant division of labour (Wills et al., 2010) but a gendered migrant division of labour. Some sectors such as household services (domestic work and care) or social reproductive labour are not only predominantly female but, especially in Southern Europe, overwhelmingly filled by migrant women. Although this type of work has attracted much attention in studies of female labour migration, other sectors, both lesser skilled and more skilled, have also relied heavily on female migrant labour but have been much less studied. Mirjana Morokvasic (2011) questioned the basis of our preoccupation about migrant women as subaltern and victims, exclusively filling low skilled sectors. Thus domestic and care workers have become the emblematic figures of globalised migrations in stark contrast to the easily mobile male IT worker (Kofman, 2013). This is not to deny that domestic and care work globally employ more migrant women than any other sector, and that demand has not grown in response to the inadequacies of public provision across different welfare regimes, leading to the search for cheap solutions to fulfil reproductive needs by using migrant workers, including men. However it does raise issues around our lack of attention to other low skilled sectors such as hospitality and contract and commercial cleaning in hospitals, offices and public spaces, which also employ large numbers of migrants. Skilled labour, especially in welfare sectors, such as education, health and social work is also sourced globally to make good shortfalls in professional reproductive labour (Kofman & Raghuram, 2015). Thus at all skill levels migrant women are employed disproportionately in diverse sectors of social reproduction in sustaining the wellbeing of the household and of society more generally.
Engendering Integration and Inclusion
Authors: Christou Anastasia , Kofman Eleonore 
Published: March 2022

AbstractIn this chapter we turn to issues of how migrants participate in society and especially their gendered aspects. Why is gender important in this regard? It is a consideration that is usually absent from both theoretical and policy discussions of what is commonly termed integration or the basis on which migrants are incorporated into a society, a term widely used across different societies but with different meanings (Rytter, 2019). Whilst integration policies might seem to be neutral, they may in effect target women and men differently and have different outcomes for them. Such policies may also apply primarily to certain categories of migrants, although the categories and nationalities change over time. As we shall see, concerns over what constitutes problematic integration vary, such as: lack of knowledge of the language of the country, non-participation in the labour market and traditional cultural and social practices transferred from societies of origin. These have generated demands to impose integration measures and contracts as conditionalities of immigration and, if applicable, to the different stages in the pathway to citizenship.
FKN Formula and Ground State Energy for the Spin Boson Model with External Magnetic Field
Authors: Hasler David , Hinrichs Benjamin , Siebert Oliver 
Published: March 2022

AbstractWe consider the spin boson model with external magnetic field. We prove a path integral formula for the heat kernel, known as Feynman–Kac–Nelson (FKN) formula. We use this path integral representation to express the ground state energy as a stochastic integral. Based on this connection, we determine the expansion coefficients of the ground state energy with respect to the magnetic field strength and express them in terms of correlation functions of a continuous Ising model. From a recently proven correlation inequality, we can then deduce that the second order derivative is finite. As an application, we show existence of ground states in infrared-singular situations.
Numerical analysis of the strip crown inheritance in tandem cold rolling by a novel 3D multi-stand FE model
Authors: Li Lianjie , Xie Haibo , Liu Tianwu , Huo Mingshuai , Li Xingsheng , Liu Xu , Wang Enrui , Li Jianxin , Liu Hongqiang , Sun Li , Jiang Zhengyi 
Published: March 2022

Abstract
The strip shape inheritance model is widely applied to improve the strip shape quality in tandem cold rolling (TCR). However, the inheritance mechanism is still currently unclear. To bridge this gap, this paper presents a new numerical method for calculating the strip crown inheritance factor. In addition, the effects of the entry strip crown on exit strip crown and flatness were quantitatively analysed at each stand in the TCR using a novel three-dimensional (3D) multi-stand elastic–plastic finite element (FE) model. The results show that the strip crown inheritance factor increases slowly from S1 (stand 1) to S3 (stand 3), while rising sharply from S3 to S5 (stand 5), reaching a peak value of 0.495 μm/μm at S5. This trend coincides with that of strip plastic rigidity, which verifies that the strip crown inheritance factor is dependent on the strip plastic rigidity. Furthermore, the variation of strip crown and flatness under different entry strip crowns from S1 to S5 is jointly influenced by the pass reduction and strip plastic rigidity. Moreover, the strip crown inheritance factor increases with the deformation resistance of the strip at both S1 and S5. These findings not only offer a fresh perspective to understand the mechanism of strip crown inheritance, but also provide an important basis for optimising the strip shape control in the TCR process.
Tenodesis yields better functional results than tenotomy in long head of the biceps tendon operations—a systematic review and meta-analysis
Authors: Vajda Mátyás , Szakó Lajos , Hegyi Péter , Erőss Bálint , Görbe Anikó , Molnár Zsolt , Kozma Kincső , Józsa Gergő , Bucsi László , Schandl Károly 
Published: March 2022

Abstract
Background
Pathology of the long head of the biceps tendon (LHBT) is a common disorder affecting muscle function and causing considerable pain for the patient. The literature on the two surgical treatment methods (tenotomy and tenodesis) is controversial; therefore, our aim was to compare the results of these interventions.

Methods
We performed a meta-analysis using the following strategy: (P) patients with LHBT pathology, (I) tenodesis, (C) tenotomy, (O) elbow flexion and forearm supination strength, pain assessed on the ten-point Visual Analog Scale (VAS), bicipital cramping pain, Constant, ASES, and SST score, Popeye deformity, and operative time. We included only randomized clinical trials. We searched five databases. During statistical analysis, odds ratios (OR) and weighted mean differences (WMD) were calculated for dichotomous and continuous outcomes, respectively, using the Bayesian method with random effect model.

Results
We included 11 studies in the systematic review, nine of these were eligible for the meta-analysis, containing data about 572 patients (279 in the tenodesis, 293 in the tenotomy group). Our analysis concluded that tenodesis is more beneficial considering 12-month elbow flexion strength (WMD: 3.67 kg; p = 0.006), 12-month forearm supination strength (WMD: 0.36 kg; p = 0.012), and 24-month Popeye deformity (OR: 0.19; p < 0.001), whereas tenotomy was associated with decreased 3-month pain scores on VAS (WMD: 0.99; p < 0.001). We did not find significant difference among the other outcomes.

Conclusion
Tenodesis yields better results in terms of biceps function and is non-inferior regarding long-term pain, while tenotomy is associated with earlier pain relief.
Risk factors of proteinuria and potentially protective effect of renin–angiotensin system inhibitors in patients with renal cell carcinoma receiving axitinib
Authors: Ikesue Hiroaki , Yamaoka Kenta , Matsumoto Ayako , Hirabatake Masaki , Muroi Nobuyuki , Yamasaki Toshinari , Kawakita Mutsushi , Hashida Tohru 
Published: March 2022

Abstract
Purpose
Patients receiving vascular endothelial growth factor–tyrosine kinase inhibitors are at a risk of developing proteinuria. Renin–angiotensin system (RAS) inhibitors exert renoprotective effects and might reduce proteinuria risk in these patients. We investigated the risk factors for and protective effect of RAS inhibitors against proteinuria in patients with renal cell carcinoma (RCC) receiving axitinib.

Methods
We retrospectively reviewed the medical records of patients with RCC receiving axitinib at Kobe City Medical Center General Hospital between September 2012 and October 2020. Patients with proteinuria ≥ 2+ at baseline were excluded. The patients were categorized into RAS inhibitor user, non-RAS inhibitor user, and non-user groups. The severity of proteinuria was graded based on the Common Terminology Criteria for Adverse Events, version 5.0. A multivariate Cox proportional hazards model was employed to identify the risk factors for developing grade ≥ 2 proteinuria.

Results
Among 42 patients, 28 received antihypertensive drugs at baseline. Among these, 17 and 11 patients were in the RAS inhibitor and non-RAS inhibitor user groups, respectively. Twenty-three patients (54.8%) developed grade ≥ 2 proteinuria. The multivariate analysis revealed that the non-RAS inhibitor user group (P = 0.001) and patients with pre-existing grade 1 proteinuria (P = 0.022) were significantly associated with the development of grade ≥ 2 proteinuria, whereas the RAS inhibitor user group was not significantly associated with it.

Conclusion
In patients with RCC receiving axitinib, pre-existing proteinuria and non-RAS inhibitor use were significantly associated with grade ≥ 2 proteinuria development. Our preliminary data should be confirmed by further studies.
Modified copper zinc ferrite nanoparticles doped with Zr ions for hyperthermia applications
Authors: Salem B. I. , Hemeda O. M. , Henaish A. M. A. , Mostafa N. Y. , Mostafa M. 
Published: March 2022

AbstractThe problem of the present work is to synthesize a nanomagnetic material with low TC below 45 °C and its particle size below 30 nm to be appropriate material for convert magnetic loss into heat energy. A series of Cu0.4Zn0.6+yZryFe2–2yO4 nanoparticles compositions where y = (0.05, 0.1) were synthesized via citrate sol–gel method. The prepared samples were characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The grains were observed from SEM confirming the crystalline structure of the ferrite which was detected by X-ray diffraction. Magnetic hysteresis loop measurements illustrate that materials exhibit soft magnetic properties at low Zr content, while at higher Zr content all materials behave as superparamagnetically without any saturation magnetization Ms. The initial magnetic permeability ($${\mu }_{i}$$

μ
i

) at frequency 10 kHz as a function of temperature was measured. A sudden change in $${\mu }_{i}$$

μ
i

appears around Curie temperature, making our samples good candidates for magnetic temperature transducer (MTT) devices. The DC resistivity for sample at y = 0.05, 0.1 was studied. The resistivity decreases linearly with increasing temperature within the given range of temperature up to 666 K for all samples. The dielectric constant of all samples is nearly independent on temperature through the range of 450 to 600 K which is a common character of ferrites. The dielectric loss was found to increase by increasing temperature, which may be related to the increase in AC conductivity. Hyperthermia measurements show the maximum specific power loss and temperature increase were 26 w/gr and 43 °C, respectively, for sample containing Zr = 0.05, after 2 min of measurements. One of the real applications of the material is that it is used as an effective method in tumor treatment by exposing the patient to external magnetic field.
The intake of flavonoids, stilbenes, and tyrosols, mainly consumed through red wine and virgin olive oil, is associated with lower carotid and femoral subclinical atherosclerosis and coronary calcium
Authors: Salazar Henry Montero , de Deus Mendonça Raquel , Laclaustra Martín , Moreno-Franco Belén , Åkesson Agneta , Guallar-Castillón Pilar , Donat-Vargas Carolina 
Published: March 2022

Abstract
Purpose
It is suggested that polyphenols back the cardiovascular protection offered by the Mediterranean diet. This study evaluates the association of specific types of dietary polyphenols with prevalent subclinical atherosclerosis in middle-aged subjects.

Methods
Ultrasonography and TC were performed on 2318 men from the Aragon Workers Health Study, recruited between 2011 and 2014, to assess the presence of plaques in carotid and femoral arteries and coronary calcium. Polyphenol intake was assessed using a validated semi-quantitative 136-item food frequency questionnaire. The Phenol Explorer database was used to derive polyphenol class intake. Logistic and linear regressions were used to estimate the cross-sectional association of polyphenols intake with femoral and carotid subclinical atherosclerosis and coronary calcium.

Results
A higher intake of flavonoids (third vs. first tertile) was associated with a lower risk of both carotid (OR 0.80: CI 95% 0.62–1.02; P trend 0.094) and femoral (0.62: 0.48–0.80, P trend < 0.001) subclinical atherosclerosis. A higher intake of stilbenes was associated with a lower risk of femoral subclinical atherosclerosis (0.62: 0.46–0.83; P trend 0.009) and positive coronary calcium (0.75: 0.55–1.03; P trend 0.131). A higher intake of tyrosols was also associated with a lower risk of positive coronary calcium (0.80: 0.62–1.03; P trend 0.111). The associations remained similar when adjusted for blood lipids and blood pressure.

Conclusion
Dietary flavonoids, stilbenes, and tyrosols, whose main sources are red wine and virgin olive oil, are associated with lower prevalence of subclinical atherosclerosis in middle-aged subjects.
Training causes activation increase in temporo-parietal and parietal regions in children with mathematical disabilities
Authors: Soltanlou Mojtaba , Dresler Thomas , Artemenko Christina , Rosenbaum David , Ehlis Ann-Christine , Nuerk Hans-Christoph 
Published: March 2022

AbstractWhile arithmetic training reduces fronto-temporo-parietal activation related to domain-general processes in typically developing (TD) children, we know very little about the training-related neurocognitive changes in children with mathematical disabilities (MD), who seek evidenced-based educational interventions. In a within-participant design, a group of 20 children (age range = 10–15 years old) with MD underwent 2 weeks of arithmetic training. Brain activation was measured using functional near-infrared spectroscopy (fNIRS) before and after training to assess training-related changes. Two weeks of training led to both behavioral and brain changes. Training-specific change for trained versus untrained (control) simple multiplication solving was observed as activation increase in the bilateral temporo-parietal region including angular gyrus and middle temporal gyrus. Training-specific change for trained versus untrained (control) complex multiplication solving was observed as activation increase in the bilateral parietal region including intraparietal sulcus, superior parietal lobule, and supramarginal gyrus. Unlike the findings of a similar study in TD children, 2 weeks of multiplication training led to brain activation increase in the fronto-parietal network in children with MD. Interestingly, these brain activation differences between the current findings and a recent similar study in TD children underlie a rather similar behavioral improvement as regards response time and accuracy after 2 weeks of training. This finding provides valuable insights into underlying mechanisms of mathematics learning in special samples and suggests that the findings in TD children may not be readily generalized to children with MD.
Evaluation of prevention behaviour and its influencing factors with respect to cancer screening
Authors: Dawid Adam , Borzikowsky Christoph , Freitag-Wolf Sandra , Herlitzius Sabine , Wenz Hans-Jürgen , Wiltfang Jörg , Hertrampf Katrin 
Published: March 2022

Abstract
Purpose
Every year, about 4.6 million people are diagnosed with cancer in Europe. However, based on preclinical changes and using appropriate examination procedures certain cancers can be detected in symptom-free patients at an early stage and treatment initiated.
In Germany, various cancer screening examinations are currently offered to the relevant age groups and sexes free of charge. Participation rates are affected by a number of factors and barriers. The study aimed at identifying potential obstacles and barriers to uptake, taking into account demographic and socio-economic variables.

Materials and methods
Data collection was conducted in the context of routine examination appointments at the City of Kiel Occupational Health Department from September 2013 to September 2014 using an anonymised questionnaire. In addition to recording socio-demographic data and tobacco consumption, the questionnaire also catalogued participation in statutory health insurance cancer screening examinations using the “stages of change” from the Transtheoretical Model. Eight potential barriers to participation were recorded.

Results
The results are based on 718 completed questionnaires. It was found that women, older age, and non-smoking status were associated with a higher probability of participating in cancer screening. It was also found that various barriers affecting (regular) participation were perceived significantly different according to the individual stages of change. This influence of the stages was moderated by gender.

Conclusion
The results showed interesting trends in the different barriers and how they are influenced by socioeconomic factors and the stages of change. Especially the stages require different gender-specific approaches to mobilisation for cancer screening.
The TCP transcription factor HvTB2 heterodimerizes with VRS5 and controls spike architecture in barley
Authors: de Souza Moraes Tatiana , van Es Sam W. , Hernández-Pinzón Inmaculada , Kirschner Gwendolyn K. , van der Wal Froukje , da Silveira Sylvia Rodrigues , Busscher-Lange Jacqueline , Angenent Gerco C. , Moscou Matthew , Immink Richard G. H. , van Esse G. Wilma 
Published: March 2022

Abstract
Key message
Understanding the molecular network, including protein-protein interactions, of VRS5 provide new routes towards the identification of other key regulators of plant architecture in barley.

Abstract
The TCP transcriptional regulator TEOSINTE BRANCHED 1 (TB1) is a key regulator of plant architecture. In barley, an important cereal crop, HvTB1 (also referred to as VULGARE SIX-ROWED spike (VRS) 5), inhibits the outgrowth of side shoots, or tillers, and grains. Despite its key role in barley development, there is limited knowledge on the molecular network that is utilized by VRS5. In this work, we performed protein–protein interaction studies of VRS5. Our analysis shows that VRS5 potentially interacts with a diverse set of proteins, including other class II TCP’s, NF-Y TF, but also chromatin remodelers. Zooming in on the interaction capacity of VRS5 with other TCP TFs shows that VRS5 preferably interacts with other class II TCP TFs in the TB1 clade. Induced mutagenesis through CRISPR–Cas of one of the putative VRS5 interactors, HvTB2 (also referred to as COMPOSITUM 1 and BRANCHED AND INDETERMINATE SPIKELET 1), resulted in plants that have lost their characteristic unbranched spike architecture. More specifically, hvtb2 mutants exhibited branches arising at the main spike, suggesting that HvTB2 acts as inhibitor of branching. Our protein–protein interaction studies of VRS5 resulted in the identification of HvTB2 as putative interactor of VRS5, another key regulator of spike architecture in barley. The study presented here provides a first step to underpin the protein–protein interactome of VRS5 and to identify other, yet unknown, key regulators of barley plant architecture.
Analysis of closed branched and intersecting cracks by the boundary element method
Authors: Fedelinski Piotr 
Published: March 2022

AbstractThe boundary element method (BEM) and a computer code for the analysis of plates with closed branched and intersecting cracks are developed. The BEM enables simple and accurate modelling of cracked plates by using boundary elements. Contact tractions between crack surfaces are computed using an iterative procedure. Stress intensity factors (SIFs) are determined using the path-independent integral. Three numerical examples are studied: a star-shaped crack in a square plate, multiple interacting cracks in an infinite plate and randomly distributed and intersecting cracks in a square plate. The examples demonstrate the simplicity of numerical modelling, the accuracy of the method and the possible applications. The influences of load directions, distances between cracks and the contact of the crack surfaces on SIF are investigated. For the plate with randomly distributed cracks, the effective elastic properties are additionally computed by considering or neglecting contact of crack surfaces. The results show that the importance of the contact procedure depends on how the cracked material is loaded.