bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of vaccination on patients with COVID-19 during the wave of Omicron in Shanghai
Authors: Yu Chen , Fengzhao Zhu , Hongmei Wu , Zeyuan Lei , Yu Liu , Yuhang Guo , Rufei Shen , Qingzhu Jia , Xiaorong Sun , Xia Wang , Caiping Song , Zhi Xu , Chunmei Luo 
Published: November 2022

BackgroundThe global health has been affected by the COVID-19 pandemic persistently, of which Omicron is currently the predominant variant. However, the impact of vaccination on Omicron remained uncertain.ObjectiveThis study sought to explore the effect of vaccination on patients infected with Omicron.MethodsA retrospective observational cohort was conducted in the largest Fangcang shelter hospital in Shanghai from April 1 to May 30, 2022. The demographics, length of hospital stay, clinical symptoms, the comorbidities and vaccination status were recorded. Clinical outcomes of the vaccinated and non-vaccinated groups were compared and analyzed.ResultsOf the 3,119 patients who fulfilled the eligibility criteria and were enrolled in the study, 2,226 (71.4%) patients had received nCoV-19 vaccine while 893 (28.6%) patients had not received it before admission. Patients in the vaccinated group had significantly shorter length of hospital stay than those in the unvaccinated group (15.48 ± 2.708 vs. 15.85 ± 3.102, p &lt; 0.001). More asymptomatic patients were observed in the vaccinated group than the non-vaccinated (70.4 vs. 64.5%, p &lt; 0.001). Further subgroup analysis demonstrated that the older the age, the more significant the difference was (p &lt; 0.005).ConclusionsVaccination was associated with a significant reduction in the severity of Omicron infection compared with no vaccination. Vaccination appears to make Omicron-infected people with milder symptoms than unvaccinated people. This suggests the potential effectiveness of current vaccines against Omicron.
A narrative-based approach to understand the impact of COVID-19 on the mental health of stranded immigrants in four border cities in Mexico
Authors: Cruz Piñeiro Rodolfo , Ibarra Carlos S. 
Published: November 2022

ObjectiveThis paper describes the impact that the different COVID-19 related restrictions have had on the mental health and wellbeing of 57 Central American and Caribbean immigrants stranded in Mexico due to the pandemic.MethodsEthnographic data was obtained through the application of in-depth interviews centered on topics such as migration history, personal experience with COVID-19 and beliefs about the pandemic. This information was further analyzed through a narrative approach and Atlas Ti.Main findingsUS Title 42 and the Migrant Protection Protocols (MPP) have stranded thousands of individuals in the US-Mexico border region, a situation that has overcrowded the available shelters in the area and forced many of the immigrants to live on the streets and in improvised encampments. Thus, exposing them to a higher risk of contagion. Furthermore, the majority of the interviewed Central American and Caribbean immigrants consider that Mexico is more lenient when it comes to the enforcement of sanitary measures, especially when compared to their countries of origin. Finally, vaccination hesitancy was low among the interviewees, mainly due to the operative aspects of the vaccination effort in Mexico and the fear of ruining their chances to attain asylum in the US. These findings are backed up by the discovery of five recurring narratives among the interviewees regarding: (1) The pandemic's psychological impact. (2) The uncertainty of being stranded in Mexico and the long wait. (3) Their fear of violence over the fear of contagion. (4) The perceived leniency of Mexico with the pandemic when compared to their countries of origin, and (5) their beliefs about the pandemic and vaccines.Key findingThe mental health of stranded Central American and Caribbean immigrants in Mexico during the COVID-19 pandemic is mostly affected by their inability to make it across the US-Mexico border using legal means.
Plant-based default nudges effectively increase the sustainability of catered meals on college campuses: Three randomized controlled trials
Authors: Boronowsky Renate D. , Zhang Angela W. , Stecher Chad , Presley Kira , Mathur Maya B. , Cleveland David A. , Garnett Emma , Wharton Christopher , Brown Daniel , Meier Adam , Wang May , Braverman Ilana , Jay Jennifer A. 
Published: November 2022

BackgroundLiterature suggests limiting consumption of animal products is key to reducing emissions and adverse planetary impacts. However, influencing dietary behavior to achieve planetary health targets remains a formidable problem.ObjectiveWe investigated the effect of changing the default meal option at catered events–from meat to plant-based–on participants' meal choices using three parallel-group, balanced, randomized controlled trials (RCT), and use these experimental results to project differences in plant-based default vs. meat default events on greenhouse gas emissions (GHGEs) (kg CO2 − eq), land use (m2), nitrogen (g N), and phosphorus (g P) footprint.MethodsData collection was performed at three catered events (n = 280) across two college campuses. The selected experimental sites used convenience sampling. Events consisted of a graduate orientation, sorority dinner, and academic conference. Eligibility of individual participants included being 18 years or older and an invitation to RSVP for an enrolled event. Participants were randomly assigned to one of two groups: the control group received a RSVP form that presented a meat meal as the default catering option; whereas the intervention group received a form that presented a plant-based meal as the default. The primary outcome of interest in each group was the proportion of participants who selected plant-based meals. To explore environmental impacts, we modeled the footprints of four hypothetical meals. Using these meals and RCT results, the impact (GHGE, land use, nitrogen, phosphorus) of two hypothetical 100-person events was calculated and compared.ResultsIn all, participants assigned to the plant-based default were 3.52 (95% CI: [2.44, 5.09]) times more likely to select plant-based meals than those assigned to the meat default. Using these results, a comparison of hypothetical events serving modeled meat-based and plant-based meals showed a reduction of up to 42.3% in GHGEs as well as similar reductions in land use (41.8%), nitrogen (38.9%), and phosphorus (42.7%).ConclusionResults demonstrated plant-based default menu options are effective, providing a low-effort, high-impact way to decrease consumption of animal products in catered events. These interventions can reduce planetary impact while maintaining participant choice.
The priority of liver resection compared with transarterial chemoembolization in hepatocellular carcinoma at BCLC B1 stage: A single-center experience
Authors: Yi Peng-Sheng , Liu Jun-Ning , Li Yong , Wu Bin , Li Jian-Shui 
Published: November 2022

BackgroundThis study aimed to compare the efficacy of liver resection (LR) and transarterial chemoembolization (TACE) in the treatment of Barcelona Clinic Liver Cancer B1 (BCLC B1) hepatocellular carcinoma.MethodsA total of 65 patients with BCLC B1 were divided into the radical (LR group) and TACE groups. Survival analysis was performed using the Kaplan–Meier method. Univariate and multivariate analyses were carried out, and the prognostic factors for survival outcomes were identified using Cox proportional analysis.ResultsThe 1-, 3-, and 5-year survival rates and the 1-, 3-, and 5-year progression-free survival (PFS) rates in the LR group (P = 0.036) were significantly higher than those in the TACE group (P = 0.027). Results of the multivariate analysis demonstrated that tumor distribution (both lobes vs. semi-liver) and treatment strategy (LR vs. TACE) were independent risk factors for the overall survival (OS) [hazard ratios (HRs): 3.926 and 0.479; P &lt; 0.05] and PFS (HR: 3.336 and 0.465, P &lt; 0.05). LR was associated with increased OS and PFS compared with TACE in patients with BCLC B1 hepatocellular carcinoma.
Evaluation of intracoronary hemodynamics identifies perturbations in vorticity
Authors: Vardhan Madhurima , Gounley John , Chen S. James , Nair Priya , Wei Wei , Hegele Luiz , Kusner Jonathan , Kahn Andrew M. , Frakes David , Leopold Jane A. , Randles Amanda 
Published: November 2022

Background and objective: Coronary artery disease (CAD) is highly prevalent and associated with adverse events. Challenges have emerged in the treatment of intermediate coronary artery stenoses. These lesions are often interrogated with fractional flow reserve (FFR) testing to determine if a stenosis is likely to be causative for ischemia in a cardiac territory. This invasive test requires insertion of a pressure wire into a coronary vessel. Recently computational fluid dynamics (CFD) has been used to noninvasively assess fractional flow reserve in vessels reconstructed from medical imaging data. However, many of these simulations are unable to provide additional information about intravascular hemodynamics, including velocity, endothelial shear stress (ESS), and vorticity. We hypothesized that vorticity, which has demonstrated utility in the assessment of ventricular and aortic diseases, would also be an important hemodynamic factor in CAD.Methods: Three-dimensional (3D), patient-specific coronary artery geometries that included all vessels &gt;1 mm in diameter were created from angiography data obtained from 10 patients who underwent diagnostic angiography and FFR testing (n = 9). A massively parallel CFD solver (HARVEY) was used to calculate coronary hemodynamic parameters including pressure, velocity, ESS, and vorticity. These simulations were validated by comparing velocity flow fields from simulation to both velocities derived from in vitro particle image velocimetry and to invasively acquired pressure wire-based data from clinical testing.Results: There was strong agreement between findings from CFD simulations and particle image velocimetry experimental testing (p &lt; 0.01). CFD-FFR was also highly correlated with invasively measured FFR (ρ = 0.77, p = 0.01) with an average error of 5.9 ± 0.1%. CFD-FFR also had a strong inverse correlation with the vorticity (ρ = -0.86, p = 0.001). Simulations to determine the effect of the coronary stenosis on intravascular hemodynamics demonstrated significant differences in velocity and vorticity (both p &lt; 0.05). Further evaluation of an angiographically normal appearing non-FFR coronary vessel in patients with CAD also demonstrated differences in vorticity when compared with FFR vessels (p &lt; 0.05).Conclusion: The use of highly accurate 3D CFD-derived intravascular hemodynamics provides additional information beyond pressure measurements that can be used to calculate FFR. Vorticity is one parameter that is modified by a coronary stenosis and appears to be abnormal in angiographically normal vessels in patients with CAD, highlighting a possible use-case in preventative screening for early coronary disease.
In Vitro Evaluation of Anti-Inflammatory and Protective Potential of an Extract from Cornus mas L. Fruit against H2O2-Induced Oxidative Stress in Human Skin Keratinocytes and Fibroblasts
Authors: Wójciak Magdalena , Zagórska-Dziok Martyna , Nizioł-Łukaszewska Zofia , Ziemlewska Aleksandra , Furman-Toczek Dominika , Szczepanek Dariusz , Sowa Ireneusz 
Published: November 2022

Cornus mas L. is a rich source of valuable compounds with pro-health properties and, therefore, may be attractive for the pharmaceutical and cosmetic industry. This paper attempts to assess the antioxidant, anti-inflammatory, and protective effect of an extract from C. mas fruit on skin cells in vitro. The phytochemical analysis of the extract was carried out using UPLC-MS and the content of the main components was determined. The biological activity of the extract was assessed by in vitro analysis using two human cell lines: keratinocytes (HaCaT) and fibroblasts (BJ). Additionally, the ability of this extract to regulate gene expression (SOD-1, Nox-4) in skin cells was evaluated. Moreover, the impact of the extract and its main components, including loganic acid and cornuside, on the level of inflammatory cytokines in H2O2-treated cells was assessed. The tests showed that the extract has strong antioxidant properties and stimulates the proliferation of both types of cells. The results evidence that the Cornus mas L. fruit extract significantly reduces the level of reactive oxygen species in the cells tested and can modulate the expression of genes closely related to oxidative stress. Moreover, it suppresses the production of IL-6, IL-8, and TNF-α, and the effect was related to loganic acid and cornuside. The present research indicates that the analyzed dogwood extract can be an effective means of prevention of cell damage caused by free radicals and have a positive effect on the condition of skin cells.
Kelapa Sawit sebagai Penyebab Bencana Ekologis - Laudato Si Artikel 29-30
Authors: . Agustinus 
Published: November 2022

Fokus penulisan artikel ini ialah perkebunan kelapa sawit sebagai kontributor terjadinya bencana ekologis di Sekadau-Kalimantan Barat ditinjau dari Laudato Si artikel 29-30. Adapun metodologi yang penulis gunakan dalam menggarap karya tulis ini yakni dengan menginput data-data melalui artikel-artikel, majalah-majalah, dan pengamatan langsung oleh penulis sendiri terkait dengan persoalan yang penulis angkat dalam karya tulis ini. Selanjutnya untuk menyempurnakan hasil dari data-data yang telah penulis peroleh tersebut, penulis akan mengkombinasikannya dengan menggunakan studi kepustakaan yakni menggunakan referensi dari buku-buku yang sesuai dengan tema yang penulis angkat dalam artikel ini. Tujuannya agar artikel ini dapat memberikan informasi-informasi baru bagi pembacanya dan dapat dipercaya. Dari studi ini penulis pun menemukan bahwa salah satu penyebab masalah air, terutama sulitnya mendapatkan air bersih di Sekadau-Kalimantan Barat, khususnya di daerah pedalaman ialah karena kehadiran dari perkebunan kelapa sawit. Air bersih sulit didapatkan oleh masyarakat karena dampak dari pupuk perkebunan kelapa sawit. Pupuk ini akan membahayakan kesehatan masyarakat, apabila pupuk tersebut tercemar di air sungai yang airnya dikonsumsi oleh masyarakat. Selain itu, air bersih juga sulit didapatkan karena seringnya banjir. Banjir ini terjadi salah satunya dampak dari pengundulan hutan yang dilakukan demi ekspansi perkebunan kelapa sawit. Akibatnya masyarakat Sekadau yang tinggal di pedalaman terpaksa harus mengkomsumsi air yang tercemar oleh banjir ini.
Model Optimasi Produksi Tambak Udang Berbasis Daya Dukung Perairan
Authors: Ningsih Ika Junia , Muqsith Abdul 
Published: November 2022

Tujuan penelitian adalah untuk menentukan kapasitas produksi dan luas blahan optimal tambak udang intensif berdasarkan daya dukung perairan pesisir Kecamatan Banyuputih dengan permodelan sistem dinamis.Analisis otimasi produksi tambak udang intensif dilakukan dengan pendekatan permodelan sistem dinamis menggunakan alat bantu software Stella ver. 9.02. Variabel yang disimulasi pada analisa pemodelan ini adalah variabel kapasitas oksigen perairan, kuantitas limbah budidaya, biomassa udang, bobot rata-rata udang, dan prosentase tingkat kelulushidupan udang selama satu siklus budidaya. Hasil simulasi model dinamis menunjukkan bahwa sistem budidaya udang intensif padat tebar (110 ekor/m2) dengan penerapan 2 (dua) kali panen parsial (pada saat umur udang 70 hari dan 90 hari) menghasilkan produktifitas biomassa udang yang paling optimal serta beban limbah TSS pada perairan pesisir yang paling kecil (sedikit) dibandingkan dengan sisitem budidaya intensif dengan tingkat padat tebar (130 ekor/m2), (150 ekor/m2), dan (170 ekor/m2). Penerapan sisitem bididaya dengan padat 110 ekor/m2 memberikan tingkat daya dukung optimal perairan untuk pengembangan lahan tambak udang intensif seluas 45 ha atau 65.4% dari daya dukung maksimal perairan (67,8 ha)dengan kapasitas produksi optimal sebesar 1.165.327,43 kg udang
ANALISIS STRUKTUR BIAYA DAN PEMASARAN USAHATANI JAGUNG MANIS (Zea mays L. Saccharata)
Authors: Wahyuni Etty , Afriani Noor 
Published: November 2022

Komoditas jagung manis memiliki prospek yang baik untuk dikembangkan, namun terdapat berbagai permasalahan dalam sistem agribisnis usahatani jagung manis yaitu lemahnya keterkaitan antar subsistem hulu sampai ke hilir seperti distribusi dan penyediaan faktor produksi, proses produksi pertanian, pengolahan dan pemasaran serta risiko pada pendapatan. Penelitian ini bertujuan untuk menganalisis struktur biaya, saluran pemasaran dan efisiensi pemasaran Jagung Manis (Zea mays L. Saccharata) di Kota Tarakan. Responden diperoleh berdasarkan metode purposive sampling dari para petani jagung manis di Kota Tarakan berjumlah 112 orang. Analisis data untuk menjawab permasalahan yang ada meliputi analisis struktur biaya, saluran pemasaran, margin pemasaran, farmer’s share dan efisiensi pemasaran. Hasil penelitian menunjukkan biaya variabel memberi kontribusi tertinggi terhadap total biaya produksi sebesar 61,39% dibandingkan biaya tetap sebesar 38,61%, dengan persentase tertinggi adalah biaya tenaga kerja dan biaya pupuk. Adapun saluran pemasaran terdiri dari 2 saluran pemasaran yaitu saluran pemasaran yang melibatkan 1 lembaga pemasaran yaitu pedagang pasar ke konsumen dan saluran pemasaran yang melibatkan 2 lembaga pemasaran yaitu pengepul dan pedagang pasar. Saluran pemasaran 1 dan 2 termasuk kategori efisien berdasarkan nilai farmer’s share yaitu 82% untuk saluran 1 dan 72% untuk saluran ke 2.Kata kunci: struktur biaya, pemasaran, jagung manis
ANALISIS WILAYAH BASIS DAN MULTIPLIER EFFECT KOMODITAS PADI DI KALIMANTAN UTARA
Authors: Hendris Hendris , Dupa Permana Syah Enggar , Fauziah Nurul 
Published: November 2022

Upaya pengembangan komoditas padi di Provinsi Kalimantan Utara perlu memperhatikan aspek kondisi setiap wilayah karena dengan melihat kondisi tersebut dapat diketahui mana saja wilayah yang basis komoditas padi, sehingga aspek perencanaan wilayah menjadi satu hal yang sangat penting karena masing-masing wilayah dengan potensi sumberdaya yang ada mempunyai nilai strategis wilayah. Tujuan penelitian ini adalah (1) mengidentifikasi wilayah basis produksi komoditas padi; (2) mengetahui karakteristik penyebaran komoditas padi; (3) mengetahui dampak pengganda (multiplier effect) komoditas padi. Metode analisis data menggunakan metode analisis Location Quotient, analisis koefisien lokalita dan spesialisasi, dan analisis Basic Service Ratio dan Regional Multiplier. Hasil penelitian menunjukkan wilayah basis produksi komoditas padi di Provinsi Kalimantan Utara adalah di Kabupaten Malinau. Penyebaran komoditas padi di Provinsi Kalimantan Utara tidak terkonsentrasi pada satu wilayah kabupaten/kota saja melainkan tersebar di seluruh wilayah dan kabupaten/kota yang ada di Provinsi Kalimantan Utara tidak menspesialisasikan komoditas padi pada satu wilayah tertentu. Berdasarkan hasil analisis Basic Service Ratio (BSR) dan Regional Multiplier (RM), komoditas padi mampu mendukung kegiatan pertanian tanaman pangan di Provinsi Kalimantan Utara. Kata kunci: BSR, LQ, Padi, Regional Multiplier
KAJIAN SISTEM AGRIBISNIS SAYURAN HIDROPONIK DALAM MENUNJANG KETAHANAN PANGAN DI KOTA TARAKAN
Authors: Jafar Rayhana , Hamriani Hamriani 
Published: November 2022

Food security will remain a fundamental problem in meeting the basic needs of the community, not only in rural areas but also in urban areas. Tarakan City is a city located in North Kalimantan and has a population density that causes limited availability of land for agriculture. One solution to overcome this is hydroponic cultivation to support food self-sufficiency in border areas. This study aims to identify and examine through an agribusiness system approach including input subsystems, farming/cultivation, processing, marketing and hydroponic business support services. The research method used is descriptive qualitative through agribusiness systems approach. The method of determining the sample is purposive sampling. The results of this study indicate that hydroponic vegetable farming in Tarakan City that the upstream subsystem includes production facilities and infrastructure such as screenhouses, seeds, nutrition, and agricultural machinery. On Farm subsystem covers an area of 10 x 15 m2 with a total income of Rp.1,373,000, per production. The downstream subsystem includes processing products such as sorting and packing and using a marketing mix approach consisting of two marketing channels. The supporting subsystem consists of government institutions, namely the Food and Agriculture Service, the Industry, Trade and SMEs Service, as well as a private institution, namely PT. Medco. Key words:, Agribusiness, Food Security, Hydroponics
EFFECTIVENESS OF COMBINATION OF BITTER GOURD (Momordica charantia L.) AND GARLIC (Allium sativum L.) EXTRACT ON MALE WHITE MICE (Mus muscullus) AS APHRODISIAC
Authors: Alfiraza Ery Nourika , Listina Osie , Gautama Tomy Sugiarto 
Published: November 2022

Aphrodisiac is a material that used to increase libido or sexual desire. The purpose of this study was to determine the effect of aphrodisiac on bitter melon fruit (Momordica charantia L.) and garlic (Allium sativum L.) in male white mice (Mus musculus L.) and at what concentration the combination of bitter melon and garlic had the best aphrodisiac effect.
Bitter melon powder and garlic were macerated with 70% ethanol for 4 x 24 hours. In this study, ICC (Introduction, Climbing, Coitus) method was used in 25 male mice divided into 5 groups. Group I as negative control was given aquadest, group II was given a single dose of bitter melon, group III a single dose of garlic, Group IV, and Group V were given a combination of bitter melon extract and garlic with ½ combination 980 mg/kg body weight: 150mg /kg body weight, Group IV, and V were given a combination of bitter melon extract and garlic with 1 combination 1960 mg/kg body weight: 300 mg/kg body weight. Each group was given oral test materials, group I, II, III, IV, and V was given extracts according to the dose for 2 hours. Then those observed and calculated the number of Introduction, Climbing, and Coitus.
The results showed that the combination of bitter melon extract and garlic group V (1960 mg/kg body weight: 300 mg/kg body weight) had the best aphrodisiac activity compared to other extract combination activities, and all extract combinations showed significantly different aphrodisiac effects.
MENINGKATKAN KETERAMPILAN SISWA DALAM MENULIS TEKS BERITA MELALUI PENERAPAN MODEL PEMBELAJARAN THINK TALK WRITE DI KELAS VIII C SMP NEGERI 1 SAGALAHERANG
Authors: Haryati Eti Sri 
Published: November 2022

Penelitian tindakan kelas ini bertujuan untuk meningkatkan hasil belajar siswa khususnya keterampilan siswa dalam menulis teks berita di kelas VIII C SMP Negeri 1 Sagalaherang melalui penerapan model pembelajaran Think Talk Write. Penelitian ini menggunakan desain PTK yang dilaksanakan dalam dua tahap, yaitu tahap siklus I dan siklus II dengan target nilai rata-rata kelas atau ketuntasan minimal 75. Subjek penelitian ini adalah siswa kelas VIII C SMP Negeri 1 Sagalaherang semester ganjil tahun pelajaran 2018/2019 sebanyak 32 siswa. Berdasarkan hasil analisis data pada pra siklus, siklus I, dan siklus II diketahui ada peningkatan hasil belajar siswa dalam menulis teks berita yang diperoleh siswa kelas VIII C. Pada siklus I rata-rata hasil tes siswa sebesar 71,56 dengan tingkat ketuntasan sebesar 53,13%. Peningkatan hasil belajar siswa terjadi pada siklus II, yaitu dengan rata-rata hasil tes yang diperoleh siswa sebesar 84,84 dengan tingkat ketuntasan sebesar 90,63%, sehingga terjadi peningkatan hasil belajar siswa sebesar 13,28 dan peningkatan tingkat ketuntasan sebesar 37,50%.