bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perguntas que importam: o gênero e as fronteiras teóricas da psicanálise
Authors: Beer Paulo , Ambra Pedro 
Published: February 2022

Cet article discute l’introduction, l’acceptation et le refus des théories sur le genre par la psychanalyse. L’axe central consiste à aborder l’articulation entre psychanalyse et études de genre dans une perspective ample, en mobilisant des débats spécifiques pour interroger la manière dont ces questions sont traitées au sein de la théorie psychanalytique. Le problème initial découle de la reconnaissance que les débats psychanalytiques sur les questions de genre sont souvent peu développés et se résument à des approches limitées et fréquemment caricaturales. Une question directrice pourrait donc être définie en ces termes : « les questions liées au genre sont-elles prises dans leur plein potentiel disruptif par les psychanalystes ou la communauté psychanalytique a-t-elle pris des positions défensives afin d’éviter un débat inconfortable » ? Ce type de questionnement conduit à réfléchir au-delà du contenu des avancées théoriques réalisées au cours des dernières décennies, pour ainsi envisager la fonction que de tels débats jouent dans la communauté psychanalytique. Cela signifie qu’analyser la manière dont ces discussions sont proposées et ont lieu pourrait indiquer des signes d’ouverture ou de refus de la psychanalyse à l’égard de ces questions. Comprendre les raisons de ce positionnement sur un sujet aussi crucial est une tâche essentielle pour les psychanalystes qui s’engagent dans la construction d’une praxis psychanalytique à la fois présente dans la culture et politiquement impliquée.
Dimensions de la vulnérabilité liée au paludisme dans deux zones de Madagascar : apports d’une approche mixte
Authors: Andrianasolo Andry Herisoa , Raboanary Emma , Mattern Chiarella , Kesteman Thomas , Pourette Dolorès , Rogier Christophe 
Published: February 2022

Le risque de décès, d’aggravation d’une maladie ou d’endettement dans ses suites, dépend des dispositifs et moyens disponibles et accessibles à la population pour y faire face. Ainsi, la vulnérabilité liée au paludisme dépend des contextes socio-économique et géoclimatique qui déterminent le risque de transmission, des comportements individuels ou collectifs, et des moyens des ménages pour faire face à la maladie, la prendre en charge ou la prévenir.La présente étude vise à identifier les déterminants de la vulnérabilité liée au paludisme de la population de Madagascar, en analysant le contexte et les comportements de prévention et de recours aux soins médicaux en cas de fièvre. Une étude quantitative sur 4 043 personnes de 803 ménages a été combinée à une étude qualitative reposant sur une soixantaine d’entretiens, dans deux districts, Ankazobe (Hautes Terres) et Brickaville (côte est), où le risque de paludisme et les contextes psycho-sociaux différaient. Les données ont été collectées en 2014 dans le cadre d’une thèse et d’une étude pluridisciplinaire, multicentrique et internationale (projet PALEVALUT1), pour laquelle un questionnaire et des guides d’entretien ont été développés, standardisés et validés.À Brickaville, les conditions bioclimatiques (chaudes et humides) sont plus favorables au développement des moustiques vecteurs du paludisme qu’à Ankazobe. La survenue de fièvre, la connaissance d’une personne décédée du paludisme, la perception de la dangerosité de cette maladie, la citation de fausses croyances à son sujet, l’utilisation de moustiquaires, le recours à un professionnel de santé et à un test sanguin pour son diagnostic, et le paiement de frais pour le déplacement vers une structure de santé ou pour obtenir des soins en cas de fièvre, y étaient significativement plus fréquents. En revanche, l’exposition à l’éducation pour la santé, la compréhension du paludisme, le recours aux agents communautaires et la prise d’une combinaison thérapeutique à base d’artémisinine en cas de prise d’antipaludique, y étaient significativement moins fréquents qu’à Ankazobe.Ainsi, à Brickaville où la prévalence du paludisme était la plus élevée, certaines connaissances, attitudes et pratiques, associées à la prévention ou au traitement étaient plus fréquentes alors que d’autres, notamment en matière thérapeutique, étaient plus souvent inappropriées. L’écosystème, la disponibilité, l’accessibilité et la nature des lieux de recours, l’exposition à l’éducation pour la santé, les pratiques médicales des soignants et des patients, différaient significativement dans ces sites distants de moins de 300 km ou entre des sous-populations d’un même site. Ces déterminants de la vulnérabilité liée au paludisme, multidimensionnels et complexes, sont présentés et discutés ici sur les plans quantitatifs et qualitatifs.
Vulnérabilités et trajectoires résidentielles des jeunes adultes en France
Authors: Zegnani Sami , Quidu Frédérique , Filhon Alexandra 
Published: February 2022

Cet article a pour objectif d’analyser la vulnérabilité sociale des jeunes adultes français. La vulnérabilité, envisagée à la fois comme un phénomène objectif et subjectif, renvoie à une situation intermédiaire entre exclusion et intégration sociale. Une attention particulière est accordée aux trajectoires résidentielles dans la mesure où la décohabitation est un élément central du processus d’entrée dans l’âge adulte. Les résultats présentés reposent sur l’exploitation de l’une des seules bases de données longitudinales proposant un volet sur la subjectivité des jeunes : l’enquête Eva (Insee). À partir d’une classification ascendante hiérarchique et des techniques d’appariement optimal, une typologie de la vulnérabilité puis une analyse des séquences résidentielles ont été élaborées. Elles montrent que l’un des sentiments de « fragilité » les plus mal vécus réside dans l’incapacité à s’émanciper de ses parents en quittant le foyer familial.
Les enfants et les adolescents sans-logement : une population doublement vulnérable face à la mobilité ?
Authors: Macchi Odile , Oppenchaim Nicolas 
Published: February 2022

L’objectif de cet article est de montrer comment les enfants et les adolescents hébergés en hôtel social font face à une double contrainte en ce qui concerne leur mobilité : ils sont confrontés, d’une part, à de nombreux déménagements et à l’absence de maîtrise de la localisation géographique de leur lieu d’hébergement ; d’autre part, cette instabilité résidentielle entraîne de nombreux déplacements quotidiens, notamment pour aller à l’école, qui sont eux-mêmes entravés par une série d’obstacles. La description de cette double contrainte nous permettra d’engager, de manière plus générale, une réflexion sur la question des inégalités sociales liées à la mobilité.
Evaluation of Cuban Bacillus thuringiensis (Berliner, 1911) (Bacillales
Authors: Rizo Aileen González , Martinez Camilo E Castañet , Cardentey Celeste Ramirez , Ibañez Ariamys Companioni , Díaz Zulema Menendez , Fidalgo Lianet Monzote , Álvarez Hilda M Hernandez 
Published: February 2022

Objective:
To evaluate 11 Cuban native Bacillus (B.) thuringiensis isolates in order to select one with the best larvicidal activity against Aedes (Ae.) aegypti and low cytotoxicity.

Methods:
The cry and cyt genes of the isolates (A21, A51, L95, L910, M29, R84, R85, R87, R89, U81 and X48) were amplified by PCR. The influence of organic matter and NaCl on the larvicidal activity was tested by bioassays. Cytotoxicity was assayed on peritoneal macrophages of BALB/c mice.

Results:
The cyt1 (Aa, Ab, Ba), cyt2, cry4aA, cry4Ba, cry11 (Aa, Ba, Bb) and cry10 genes were identified in all native Cuban isolates. The larvicidal activity (LC90) of seven isolates was affected by the presence of organic matter in the water, while A21, A51, L910, R84, U81 and X48 had better LC50, LC90, LC95 than the 266/2 9-VII-98 control strain. The LC50 of two isolates was affected by the presence of NaCl and A21, A51, R85 isolate had better larvicidal activity than the 266/2 9-VII-98 control strain. In terms of toxicity against macrophages, the extracts of nine isolates were less cytotoxic than the control strains.

Conclusions:
Native isolate A21 had the main virulence factors against Ae. aegypti larvae, displayed a good larvicidal activity in presence of different factors related with Ae. aegypti breeding sites, and had low citotoxicity against macrophages. These results can contribute to the improvement of existing biological control strategies and the development of new biolarvicides.
Immunohistochemical and mutational status of telomerase reverse transcriptase in conjunctival squamous cell carcinoma
Authors: Jayaraj Perumal , Sen Seema , Saxena Kartikey , Gupta Jassika , Vats Pranjal , Kashyap Seema , Chauhan Sheetal , Pushker Neelam 
Published: February 2022

Purpose:
Mutations in human telomerase reverse transcriptase (TERT) are associated with increased telomerase activity in cutaneous melanomas. Conjunctival squamous cell carcinoma, also referred to as ocular surface squamous cell carcinoma, is cancer on the surface of the eye. Recent studies have identified UV signature mutations in TERT promoters in ocular melanoma and ocular surface squamous neoplasia. However, its immunohistochemical status has not been reported in ocular surface squamous cell carcinoma. This study aimed to explore the immunohistochemical and mutational status of TERT in ocular surface SCC.

Methods:
The immunohistochemical expression of TERT and mutational status of TERT promoter was evaluated in 19 ocular surface squamous cell carcinoma cases. Conjunctival melanoma tissue was used as a positive control.

Results:
The cytoplasmic overexpression of TERT was detected in 11/19 (57%), and TERT promoter mutations were identified in 6/19 (31%) of ocular surface squamous cell carcinoma. Out of these, 66% had a C228T mutation, and 33% had a C250T mutation. The TERT expression was found to be associated with a high (≥T3) AJCC category (P = 0.023), and TERT immunoexpression was significantly correlated with reduced disease-free survival (P = 0.024, log-rank analysis) in ocular surface squamous cell carcinoma patients.

Conclusion:
The present study demonstrates that TERT promoter mutations with UV signatures are frequent in ocular surface squamous cell carcinoma. The increased expression of TERT could be of biological significance in aggressive ocular surface squamous cell carcinoma.
Comparison of the clinical outcomes of Eyecryl™ and Tecnis® toric intraocular lenses: A real-world study
Authors: Thulasidas Mithun , Sasidharan Ajita , Pradeep Balam 
Published: February 2022

Purpose:
To compare the postoperative uncorrected distance visual acuity (UDVA) and refractive outcomes of cataract patients with astigmatism following implantation of Eyecryl™ and Tecnis® toric intraocular lenses (IOLs).

Methods:
We conducted a single-center, retrospective study including patients who had undergone phacoemulsification and implantation with either Eyecryl™ toric (Group 1) or Tecnis® toric (Group 2) IOL. The primary outcome measures included postoperative UDVA and residual astigmatism at 3 months. The secondary outcome measure was IOL misalignment >10° throughout the follow-up period.

Results:
One hundred and eight eyes of 76 patients (44 males and 32 females) were analyzed. Twenty-nine patients (38 eyes) received Eyecryl™ toric IOL (Group 1), and 47 patients (70 eyes) received Tecnis® toric IOL (Group 2). Groups 1 and 2 showed a mean postoperative logMAR UDVA of 0.09 ± 0.11 and 0.06 ± 0.09, respectively, at 3 months (P = 0.114). In both groups, all the eyes achieved a postoperative UDVA of ≤0.3 logMAR. The postoperative residual astigmatism of group 1 and group 2 was -0.29 ± 0.34 D and -0.16 ± 0.27 D, respectively (P = 0.038). Postoperative astigmatism was within ± 1.00 D in all the eyes. No eyes had an IOL misalignment >10° throughout the follow-up period.

Conclusion:
Both Eyecryl™ and Tecnis® toric IOLs provided significant improvement in uncorrected visual acuity and astigmatism correction postoperatively. The Tecnis® toric IOL provided statistically significant lower residual astigmatism than Eyecryl™toric IOL. However, the difference in postoperative astigmatism between the two IOLs was clinically insignificant.
Long-term outcomes and risk factors for failure of glaucoma filtering surgery in eyes with vernal keratoconjunctivitis and steroid-induced glaucoma
Authors: Senthil Sirisha , Rao Harsha L , Ali Mohammed Hasnat , Krishnamurthy Rashmi , Dikshit Siddharth , Choudhari Nikhil , Sastry Ramyasri , Garudadri Chandrashekar 
Published: February 2022

Purpose:
To report outcomes and assess the risk factors for failure of trabeculectomy (trab), trabeculectomy with mitomycin-C (trabMMC), and combined trabeculectomy with cataract extraction (CT) in vernal keratoconjunctivitis (VKC) eyes with steroid-induced glaucoma (SIG).

Methods:
Trab was performed in 45 eyes of 30 subjects, trabMMC in 36 eyes of 25 subjects, and CT in 34 eyes of 27 subjects. Success was complete when intraocular pressure (IOP) was between 6 and 21 mm Hg without anti-glaucoma medications (AGM) and qualified with AGM.

Results:
Median age (14 vs. 16.3 and 17.4 years) was significantly less in the trab cohort (P = 0.007). Majority (88%–93%) were male (P = 0.78). Preoperatively, median duration of steroid usage was >2 years (P = 0.52), mean IOP (32, 29.4, and 28.4; P = 0.26) and median cup:disc ratio (CDR) (0.9; P = 0.27) were similar in the three groups. Complete success (76%, 71%, and 66% at 5 years; P = 0.91), and qualified success (88%, 97%, and 94% at 5 years; P = 1.0) with trab, trabMMC, and CT, respectively, were similar. Preoperative factors significantly associated with qualified failure (multiple logistic regression) were older children, longer duration of VKC, longer duration and mixed type of steroid use (all P < 0.001) and larger CDR (P < 0.02). At the last follow-up, 38% in trab, 33% in trabMMC, and 50% eyes in CT were blind (visual acuity ≤20/400 and/or visual field ≤10°) due to glaucoma (P = 0.33).

Conclusion:
The surgical success for all three types of surgery was similar at 5-years. Chronic VKC and long-term steroid use were associated with surgical failure. The majority had advanced disease and a significant proportion were blind due to glaucoma.
Digital eye strain and its associated factors in children during the COVID-19 pandemic
Authors: Demirayak Bengi , Yılmaz Tugan Büşra , Toprak Muge , Çinik Ruken 
Published: February 2022

Purpose:
This study was undertaken to identify the prevalence of symptoms related to the use of display devices and contributing factors in children engaged in distance learning during the COVID-19 pandemic.

Methods:
An online electronic survey form was prepared using Google Forms (Alphabet Co., Mountain View, CA) and sent to parents of children under the age of 18 years engaged in distance learning during the COVID-19 pandemic. The types of display devices children use, how often such devices are used, the symptoms of digital eye strain, and the severity and frequency of the symptoms were recorded, and the associations between the factors were analyzed.

Results:
A total of 692 participants were included. The mean age of the children was 9.72 ± 3.02 years. The most common display devices used were personal computers (n = 435, 61.7%) for online classes and smartphones (n = 400, 57.8%) for nonacademic purposes. The mean duration of display device use was 71.1 ± 36.02 min without a break and 7.02 ± 4.55 h per day. The most common reported symptom was headache (n = 361, 52.2%). Of the participants, 48.2% (n = 332) reported experiencing 3 or more symptoms. The multivariate analysis detected that being male (P = 0.005) and older age (P = 0.001) were independent risk factors for experiencing 3 or more symptoms.

Conclusion:
The increasing use of digital devices by children is exacerbating the problem of digital eye strain in children as a side effect of online learning. Public awareness should be improved.
International Council of Ophthalmology-Small Incision Cataract Surgery rubric: A roadmap to evaluate cataract surgical skill acquisition during residency training
Authors: Jariwala Shivani B , Kapadia Priti R Rameshbhai , Patel Hiteshree R 
Published: February 2022

Purpose:
The International Council of Ophthalmology-Small Incision Cataract Surgery (ICO-SICS) rubric is a tool to grade SICS steps from novice to competent. The study aimed to evaluate the progress of residents’ surgical skills by using the ICO-SICS rubric and the perceptions of residents and faculties about its use.

Methods:
This prospective educational interventional study, done in the Ophthalmology department between September 2019 and February-2020 included 14 residents and five faculties. Faculties scored residents’ SICS by ICO-SICS-rubric (four sessions/resident) and helped them identify three steps as “area of focus” to work upon. Feedback was taken using a semi-structured pretested questionnaire. Focus group discussion was done for residents. Data were entered in MS Excel and analyzed using SPSS. Perception analysis presented as percentage of written responses.

Results:
Step-wise rubric score showed improvement for initial SICS steps and wound closure (P < 0.05). Critical surgical steps and scores for three areas of focus steps showed no statistically significant improvement. Three steps as an area of focus changed partly for 11 residents and completely for three residents at the end of 6 months. Perception analysis of faculty and residents showed that the ICO-SICS rubric is a good tool to record surgical performance, identify steps needing improvement and provide structured feedback hence opined to continue it. Residents considered it as an effective learning and assessment tool.

Conclusion:
ICO-SICS rubric is a good teaching tool and helps to assess the progress of surgical skills. Identification of areas of poor performance and feedback given motivates them to focus on those areas leading to continuous professional development, resulting in competent surgeons performing SICS surgery independently at the end of the residency.
Make in India: Normative data for automated perimetry
Authors: Israni Neeraj , Thomas Rwituja , Kochar Shruti 
Published: February 2022

Background:
The normative data set in authomated perimetry is predominantly of non-Indian origin and hence may not be an accurate basis for visual field analysis in Indian population. This video describes an attempt to create a native normative dataset for automated perimetry, which can then be fed in our machines and be used as the normative database.

Purpose:
To formulate normative data and to increase domain knowledge of normative values for automated perimetry in Indian population of different age groups.

Synopsis:
Cross-sectional study conducted on patients receiving outpatient care in a span of 3 years, which included 6586 healthy normal patients (13172 eyes) with vision 6/6 unaided or after refractive correction. The patients were tested with 30-2 SITA FAST threshold algorithm on Humphrey Field Analyzer Model no: 745i. Normative data was calculated on basis of age group ranging from 19-75 years categorized to every decade. Normal values were formulated on basis of perimetry performed on normal patients.

Highlights:
Our work on creating a native normative dataset may add value as well as increase the accuracy of perimetry analysis in Indian eyes.

Online Video Link:

https://youtu.be/jqgC2Tn7HIg
Open globe injuries from projectile impact: Initial presentation and outcomes
Authors: Scanzera Angelica C , Leiderman Yannek I , Cortina Maria S , Shorter Ellen S 
Published: February 2022

Purpose:
To describe the characteristics and correlates of open globe injuries secondary to projectile injury and outcomes following surgical open globe repair at an urban tertiary referral center.

Methods:
Records of all patients with a history of open globe injury secondary to projectile injury and surgical open globe at a tertiary referral hospital between January 1, 2010 and December 31, 2016 were reviewed. Demographics, type of trauma, wound extent, presence of foreign body, and presenting clinical findings are reported. Outcomes for patients with greater than 6 months of follow-up included additional surgeries, final visual acuity, and clinical findings.

Results:
Of 214 patients who underwent open globe repair, 73 (34.1%) were due to projectile impact. Mean age was 37.9 years and patients were primarily male (n = 66, P < 0.001). Most injuries resulted in globe laceration (68.5%, P < 0.001), and wound extent was zone 1 (45.2%), zone 2 (20.5%), zone 3 (27.4%), or unknown (6.8%). Associated findings included foreign body (35.6%) and orbital fracture (15%). Of 41 patients with at least 6 months of follow-up, 70% had additional surgeries following their initial surgical repair. Laceration injuries tended to be more anterior (P = 0.002) with better visual outcomes (P = 0.045) than those with globe rupture, and concomitant orbital fracture associated with poor visual outcomes. Overall, 58.5% of patients had 20/40 or better final best-corrected visual acuity.

Conclusion:
This is the largest report of open globe injury due to projectile impact. Visual prognosis in this population is very good, with most patients achieving better than 20/40 vision in our study.
Ocular features of patients with Parkinson’s disease examined at a Neuro-Optometry Clinic in a tertiary eye care center
Authors: K Kwan Singson C , Atiya Ayisha , Hussaindeen Jameel Rizwana , Praveen Smita , Ambika Selvakumar 
Published: February 2022

Purpose:
To report the ocular features of patients with PD who presented with visual complaints to a tertiary eye care center.

Methods:
This was a retrospective study carried out between January 2015 and March 2020 at the Neuro-Optometry clinic of a tertiary eye care center in Southern India. All PD patients with ocular complaints examined by the neuro- ophthalmologists were referred to Neuro-Optometry Clinic for detailed evaluation. Patients with other neurodegenerative disorders, brain injury, and other causes of vision loss or extraocular motility disorders were excluded.

Results:
A total of 43 patients (7 females, 36 males) between 50 and 86 years of age (mean: 70 ± 8.9 years) with a mean duration of PD of 4.5 ± 4.5 years were studied. Decreased vision associated with reading difficulty (40%) was common in PD patients. In terms of gaze restriction, vertical gaze involvement (35%) was more than horizontal involvement (7%). Convergence insufficiency (CI) was the most common binocular vision dysfunction (30%), followed by CI with oculomotor dysfunction (14%) and vertical gaze palsy (18%). Ground prisms were recommended for 26 patients (61%) and home vision therapy for 5 patients (12%) as corrective measures.

Conclusion:
Binocular vision dysfunction is highly prevalent among PD patients. This could potentially contribute to the reading difficulties and double vision encountered by these patients. Assessment of binocular vision and oculomotor parameters thus becomes important to understand and manage the reading difficulties in patients with PD.