bluuebunny/crossref_metadata_2025_split huggingface dataset:
Public Policy Research—Born in the USA, at Home in the World?
Authors: Bandelow Nils C. , Herweg Nicole , Hornung Johanna , Zohlnhöfer Reimut 
Published: May 2022

AbstractPublic policy emerged as an academic subfield in the United States after the second World War. The theoretical foundations of the discipline are essentially based on analyses of Anglo-Saxon policies and politics and were originally aimed at providing knowledge for the policy process of pluralistic democracies. Given the increasing transfer of the subject and related approaches to other countries, it is necessary to clarify how suitable theories, goals, and methods of policy research are applied in other contexts. What needs to be considered when transferring theories of the policy process, and what can be learned from existing applications of the various approaches in different settings? The compilation of contributions on selected theoretical public policy lenses and their transfer to other countries and regions provides a nuanced answer to these questions.
Cold Spray: Over 30 Years of Development Toward a Hot Future
Authors: Guo D. , Kazasidis M. , Hawkins A. , Fan N. , Leclerc Z. , MacDonald D. , Nastic A. , Nikbakht R. , Ortiz-Fernandez R. , Rahmati S. , Razavipour M. , Richer P. , Yin S. , Lupoi R. , Jodoin B. 
Published: May 2022

AbstractCold Spray (CS) is a deposition process, part of the thermal spray family. In this method, powder particles are accelerated at supersonic speed within a nozzle; impacts against a substrate material triggers a complex process, ultimately leading to consolidation and bonding. CS, in its modern form, has been around for approximately 30 years and has undergone through exciting and unprecedented developmental steps. In this article, we have summarized the key inventions and sub-inventions which pioneered the innovation aspect to the process that is known today, and the key breakthroughs related to the processing of materials CS is currently mastering. CS has not followed a liner path since its invention, but an evolution more similar to a hype cycle: high initial growth of expectations, followed by a decrease in interest and a renewed thrust pushed by a number of demonstrated industrial applications. The process interest is expected to continue (gently) to grow, alongside with further development of equipment and feedstock materials specific for CS processing. A number of current applications have been identified the areas that the process is likely to be the most disruptive in the medium-long term future have been laid down.
A Revision of the Sb-Te Binary Phase Diagram and Crystal Structure of the Modulated γ-Phase Field
Authors: Solé Stefan , Schmetterer Clemens , Richter Klaus W. 
Published: May 2022

AbstractA new experimental study of Sb-Te, based on long term annealed samples homogenized by intermediate powdering and re-annealing of the pressed powder pellets was performed. More than 25 samples were prepared, covering the entire composition range between 0 and 60 at.% Te. This part of the phase diagram was disputed for many years, as the number of phases and their crystal structures were uncertain. Samples were characterized by optical microscopy, SEM/EDX, powder XRD and DTA. Our results show the existence of a continuous single phase field (γ) ranging from 11.4 to 56.9 at.% Te at 520 °C. A comparison of all obtained diffraction patterns showed clear evidence for a continuously modulated crystal structure. It was possible to refine all powder patterns by applying a structural model in the (3 + 1)-dimensional super-space group R­3m(0,0,γ). Lattice parameters of the basic cell as well as the modulation vector are varying continuously throughout the phase field and the γq-component ($${\mathbf{q}} = \gamma_{q} \cdot {\mathbf{c}}^{\user2{*}}$$

q
=

γ
q

·

c

∗

) of the incommensurate q-vector shows a linear extrapolation to pure Sb (γq = 3/2) and Sb2Te3 (γq = 6/5). In agreement with previous authors, the single-phase field γ was found to have a melting point minimum (30 at.% Te, 535 °C). Furthermore, two peritectic reactions were observed and the course of liquidus lines was determined in the whole investigated composition range. The new phase diagram differs considerably from all previous versions, and, for the first time, gives a complete rationalization of the crystal structures observed in the debated composition area.
Is poor sleep quality associated with poor neurocognitive outcome in cancer survivors? A systematic review
Authors: Drijver A. Josephine , Oort Quirien , Otten René , Reijneveld Jaap C. , Klein Martin 
Published: May 2022

Abstract
Purpose
Cancer-related neurocognitive impairment and poor sleep are prevalent in cancer survivors and have a negative impact on their quality of life. This systematic review studies the association between sleep disturbance and neurocognitive functioning, as well as the potential positive effects of sleep interventions on neurocognitive functioning in cancer survivors. In addition, we aimed at determining the potential positive effects of sleep interventions on neurocognitive functioning in this population.

Methods
Following PRISMA guidelines for reporting systematic reviews and meta-analyses, a comprehensive PubMed, Embase, PsycINFO, and CINAHL search was performed. Inclusion criteria were adult cancer survivors, self-reported or objective measures of neurocognitive functioning and sleep quality, or reports on the association between sleep and neurocognitive functioning.

Results
Of the 4,547 records retrieved, 17 studies were retained for this review. Twelve studies were correlational, and five reported on interventions aimed at improving sleep quality. All studies that included self-reported neurocognitive functioning found that poorer sleep was associated with worse neurocognitive functioning. In four out of eight studies, poorer sleep was associated with objective neurocognitive impairment. Three out of five interventional studies showed neurocognitive functioning improved with improved sleep.

Conclusions
While poor sleep in cancer survivors is associated with self-reported neurocognitive impairment, the association between poor sleep and objective neurocognitive impairment is less evident.

Implications for Cancer Survivors
It is important that care providers are aware of the association between sleep and neurocognitive functioning and that improving sleep quality can be a way to decrease neurocognitive impairment in cancer survivors.
Chromoendoscopy in Combination with Random Biopsies for Patients with Pathogenic CDH1 Mutations Undergoing Endoscopic Surveillance
Authors: Ruf Benjamin , Roggia Cristiana , Schroeder Christopher , Mattern Sven , Fend Falko , Klag Thomas , Götz Martin 
Published: May 2022

Abstract
Objectives
Germline mutations in the CDH1-gene are identified as the cause of 30–40% of cases of hereditary diffuse gastric cancer, an autosomal-dominant inherited cancer predisposition syndrome. Given this high risk of developing diffuse gastric cancer, carriers of a pathogenic CDH1 germline mutation are advised to undergo prophylactic gastrectomy. For patients preferring conservative management, endoscopic surveillance is recommended. The detection of diffuse gastric cancer using white light endoscopy, however, remains challenging.

Methods
Patients with pathogenic CDH1 mutation underwent (chromo)endoscopic surveillance or endoscopy prior to surgery. Biopsies were taken at suspicious sites identified by chromoendoscopy. In addition, endoscopically normal areas were assessed with mapping biopsies. Detection rates from endoscopic biopsies (mapping vs. targeted) and gastrectomy specimen were then compared.

Result
Between 11/2015 and 12/2020, ten patients from four families with a known CDH1 germline mutation had a total of n = 24 endoscopies with n = 518 total biopsies being examined. Three patients were diagnosed with GC during the study period. These patients all had suspicious chromoendoscopic lesions (= detection rate 100%). In two of three patients who had suspicious chromoendoscopic lesions, signet cell carcinoma was also detected in mapping biopsies and multiple additional cancer foci were identified in the gastrectomy specimen.

Conclusion
Chromoendoscopy facilitated detection of gastric carcinoma foci in CDH1 mutation carriers. Chromoendoscopy identified all patients with gastric cancer, but not all cancer foci present in these patients. We conclude that for patients opting against prophylactic total gastrectomy, the addition of chromoendoscopy to white light could be used to enhance diagnostic reliability of endoscopic surveillance.
A meta-analytic investigation of the impact of curiosity-enhancing interventions
Authors: Schutte Nicola S. , Malouff John M. 
Published: May 2022

AbstractCuriosity is associated with a number of beneficial outcomes, such as greater life satisfaction, more work engagement and better academic performance. The connection between curiosity and beneficial outcomes supports the importance of examining whether it is possible to increase curiosity and to investigate what approaches may be effective in facilitating curiosity. This meta-analysis consolidated the effects of curiosity-enhancing interventions. Across 41 randomized controlled trials, with a total of 4,496 participants, interventions significantly increased curiosity. The weighted effect size was Hedges' g = 0.57 [0.44, 0.70]. These results indicated that interventions were effective across a variety of intervention principles used, with participants in various age groups, across various measures, and over different time periods. Interventions aiming to increase general curiosity showed larger effect sizes than interventions aiming to increase realm-specific curiosity. Interventions incorporating mystery or game playing had especially high effect sizes. Because higher levels of curiosity tend to be associated with various beneficial outcomes, the finding that across studies interventions are effective in increasing curiosity holds promise for future efforts to increase curiosity to bring about additional benefits.
Biosynthesis of gold nanoparticles using leaf extract of Dittrichia viscosa and in vivo assessment of its anti-diabetic efficacy
Authors: Ayyoub Sanaa , Al-Trad Bahaa , Aljabali Alaa A. A. , Alshaer Walhan , Al Zoubi Mazhar , Omari Sahar , Fayyad Diaa , Tambuwala Murtaza M. 
Published: May 2022

AbstractSeveral studies have reported the anti-diabetic effect of biologically synthesized gold nanoparticles (AuNPs). This study was designed to investigate the in vivo anti-diabetic activity of AuNPs synthesized using the leaf extract of Dittrichia viscosa in a high-fat diet (HFD)/streptozotocin (STZ)-induced diabetes in rats. AuNPs were synthesized using the leaf extract of D. viscosa, and the synthesized AuNPs were characterized by UV–visible spectrophotometer, dynamic light scattering (DLS), zeta potential, and transmission electron microscopy (TEM). To study the anti-hyperglycemic effect of the AuNPs formed using D. viscosa extract, adult male Sprague–Dawley rats were divided into three groups (6–8 rats/group) as follows: control group, a diabetic group without treatment, and a diabetic group treated intraperitoneally with a daily injection of AuNPs at a dose of 2.5 mg/kg for 21 days. Diabetes was induced by maintaining the rats on HFD for 2 weeks, followed by a single intraperitoneal injection of 45 mg/kg of STZ. Serum and liver samples were collected at the end of the treatment period and used to measure glucose levels and hepatic gene expression and activity of phosphoenolpyruvate carboxykinase (PEPCK), the rate-limiting enzyme in the liver gluconeogenic pathway. The AuNPs formed using D. viscosa extract were mainly spherical with a size range between 20 and 50 nm with good stability and dispersity, as indicated by the zeta potential and DLS measurements. Treatment with AuNP significantly lowered the blood glucose level, the gene expression, and the activity of hepatic PEPCK in comparison to the diabetic untreated group (P < 0.05). This study suggests that AuNPs synthesized using D. viscosa leaf extract can alleviate hyperglycemia in HFD/STZ-induced diabetes in rats, which could be through the reduction of hepatic gluconeogenesis by inhibiting the expression and activity of the hepatic PEPCK gene.
Graphical abstract
Schematic illustration of the biosynthesis of AuNPs showing their distinctive morphology under the EM. The generated particles were injected into animals and serum glucose levels were reported in addition to the PEPCK expression and activity
Calcium acts as a central player in melatonin antitumor activity in sarcoma cells
Authors: Sánchez-Sánchez Ana M. , Turos-Cabal María , Puente-Moncada Noelia , Herrera Federico , Rodríguez Carmen , Martín Vanesa 
Published: May 2022

AbstractPurposeChondrosarcoma and osteosarcoma are the most frequently occurring bone cancers. Although surgery and chemotherapy are currently clinically applied, improved treatment options are urgently needed. Melatonin is known to inhibit cell proliferation in both tumor types. Although the underlying mechanisms are not clear yet, calcium homeostasis has been reported to be a key factor in cancer biology. Here, we set out to investigate whether regulation of calcium by this indolamine may be involved in its antitumor effect.MethodsCell viability was measured using a MTT assay and flow cytometry was used to measure levels of cytosolic calcium, intracellular oxidants, mitochondrial membrane potential and cell cycle progression. Mitochondrial calcium was analyzed by fluorimetry. Cell migration was determined using a scratch wound-healing assay. Western blot analysis was used to assess the expression of proteins related to cell cycle progression, epithelial to mesenchymal transition (EMT), Ac-CoA synthesis and intracellular signaling pathways.ResultsWe found that melatonin decreases cytosolic and mitochondrial Ca2+levels, intracellular oxidant levels, mitochondrial function and the expression of the E1 subunit of the pyruvate dehydrogenase complex. These changes were found to be accompanied by decreases in cell proliferation, cell migration and EMT marker expression. The addition of CaCl2prevented the changes mentioned above, while co-treatment with the calcium chelator BAPTA enhanced the effects.ConclusionsOur data indicate that regulation of calcium homeostasis is a key factor in the inhibition of cell proliferation and migration by melatonin. This effect should be taken into consideration in combined therapies with traditional or new antitumor compounds, since it may circumvent therapy resistance.
Description of sand–metal friction behavior based on subloading-friction model
Authors: Ozaki Toshiyuki , Yamakawa Yuki , Ueno Masami , Hashiguchi Koichi 
Published: May 2022

AbstractA subloading-friction model is formulated to describe the smooth transient variation from static friction to kinetic friction, the recovery to static friction after the sliding velocity decreases, and the accumulation of sliding displacement under the cyclic loading of contact stress. In the past relevant studies, however, the model formulation used for simulations is limited to the hypoelastic-based plasticity framework, and the validation of the model is limited to simulations of the test data for metal-to-metal friction. In this study, the formulation of the subloading-friction model based on a hyperelastic-based plasticity framework is adopted. In the fields of civil, geotechnical, agricultural engineering, and terramechanics, the interaction between soils and metals is critical, as reflected in construction and agricultural machinery, foundation piles, and retaining walls. The validity of the model for describing the friction between various sands and metals is verified by simulations of the experimental data under monotonic and cyclic loadings.
The calculation of flushing time for the upper Pasur River Estuary, Bangladesh
Authors: Shaha Dinesh Chandra , Cho Yang-Ki , Kundu Sampa Rani , Hasan Jahid , Haque Farhana , Salam Mohammad Abdus 
Published: May 2022

AbstractEstimation of estuarine flushing time, a time required to transport of pollutants or any other properties from estuaries to the coast, is very important for its resource management. In this study, we estimated flushing time (T) of the upper Pasur River Estuary (UPRE) for understanding the water quality condition in the dry and wet seasons. High-resolution salinity data were collected from the PRE at high water in the dry and wet seasons in 2014 and 2019. Flushing time was calculated using the freshwater fraction method (FFM) as well as e-folding flushing time scales was estimated empirically using the salinity (non-reactive conservative) and monthly river discharge data. System flushing during the dry season was thirteen times weaker than flushing during the wet season owing to decreasing river discharge by nearly 94%. In addition, the daily exchange volume was decreased by eight times during the dry season than during the wet season. As a consequence, the conditions of the UPRE are more dynamic during the wet season due to receiving huge amount of river discharge. During the dry season, only the e-folding time scales showed higher values in the salinity maximum zone (salt plug area). This implied that the e-folding time scale is an empirical approach and was able to encompass the tidal dispersion process whereas the FFM was unable to include that process. As the PRE is a macrotidal estuary, the tide assists to flush dissolved substances from the UPRE to the coast during the dry season having negligible river discharge. In addition, there was no significant variation in water quality parameter between the salt plug area (SP) and downstream of salt plug area (DSP) during the dry season. In order to have more accuracy, a three-dimensional hydrodynamic model would be useful to compute estuarine time scales precisely.
A comparison of active versus passive methods of responding to rapid diagnostic blood culture results
Authors: Chandler Elisabeth L. , Wallace Katie L. , Palavecino Elizabeth , Beardsley James R. , Johnson James W. , Luther Vera , Ohl Christopher , Williamson John C. 
Published: May 2022

Abstract

Objective:
To compare 2 methods of communicating polymerase chain reaction (PCR) blood-culture results: active approach utilizing on-call personnel versus passive approach utilizing notifications in the electronic health record (EHR).

Design:
Retrospective observational study.

Setting:
A tertiary-care academic medical center.

Patients:
Adult patients hospitalized with ≥1 positive blood culture containing a gram-positive organism identified by PCR between October 2014 and January 2018.

Methods:
The standard protocol for reporting PCR results at baseline included a laboratory technician calling the patient’s nurse, who would report the critical result to the medical provider. The active intervention group consisted of an on-call pager system utilizing trained pharmacy residents, whereas the passive intervention group combined standard protocol with real-time in-basket notifications to pharmacists in the EHR.

Results:
Of 209 patients, 105, 61, and 43 patients were in the control, active, and passive groups, respectively. Median time to optimal therapy was shorter in the active group compared to the passive group and control (23.4 hours vs 42.2 hours vs 45.9 hours, respectively; P = .028). De-escalation occurred 12 hours sooner in the active group. In the contaminant group, empiric antibiotics were discontinued faster in the active group (0 hours) than in the control group and the passive group (17.7 vs 7.2 hours; P = .007). Time to active therapy and days of therapy were similar.

Conclusions:
A passive, electronic method of reporting PCR results to pharmacists was not as effective in optimizing stewardship metrics as an active, real-time method utilizing pharmacy residents. Further studies are needed to determine the optimal method of communicating time-sensitive information.
Transplanting EU competition law in ASEAN: Towards a context informed method of investigation
Authors: Gideon Andrea 
Published: May 2022

AbstractWhen reading the competition law statutes of countries such as Singapore, Malaysia, Brunei Darussalam or, to a lesser extent, the Philippines, it quickly becomes clear to anyone who has studied EU competition law in any detail that these statutes have been inspired by or, indeed, partly been copied verbatim from EU competition law. Yet, do these transplants actually work the same way in the receiving countries? Is that even possible at all? And how are we to understand any deliberate changes which have been made to the transplants?The article aims to develop a method for investigating EU competition law transplants in non-EU countries, focusing especially on ASEAN, based on inter-disciplinary insight into the social, cultural, political, and economic contexts in the receiving countries. For this, the article engages with the theoretical underpinnings of legal transplants and comparative law. It has become increasingly well-recognised in critical comparative legal research that it is essential to go beyond the legal perspective, but this is still rare in competition law comparison. A sound method taking into consideration legal and non-legal contexts will help us to understand more fully the role of competition law in those non-EU countries that have opted to transplant the EU model.
Educational assortative mating and income inequality in Thailand
Authors: Paweenawat Sasiwimon Warunsiri , Liao Lusi 
Published: May 2022

AbstractThis study examines the degree of educational assortative mating, its evolution, and its relationship with income inequality in Thailand using national labor force survey data from 1985 to 2016. Since the 1990s, Thailand shows a trend of decreasing educational homogamy, but there is evidence of continuing educational hypergamy in Thai households. Using the semiparametric decomposition method of DiNardo, Fortin and Lemieux (1996), the study finds that educational assortative mating has affected changes in household income inequality over time. Furthermore, there exists a negative relationship between income inequality and marital sorting with same education, which contradicts evidence found in developed countries.
Multi-Faceted Approach to COVID-19 Surveillance at a Large University Campus in the Southeastern United States
Authors: Klann Emily M. , Rich Shannan N. , Hendrick Sabrina C. , Felipe Alfeil , Sathish Sneha , Prins Cindy , Lauzardo Michael , Shapiro Jerne 
Published: May 2022

Abstract
The coronavirus disease 2019 (COVID-19) pandemic continues to present unique public health challenges both within the United States and across the globe. Institutions of higher learning are tasked with preventing and responding to COVID-19 on campus while also considering implications for the surrounding communities. The process of re-opening campus, whether at full or partial capacity, has tasked these institutions with overcoming complex challenges associated with balancing the resumption of campus operations while simultaneously protecting university affiliates and surrounding community members from COVID-19 through robust surveillance, contact tracing, and testing efforts. Here, we provide a concise outline related to the development and implementation of the comprehensive and sustainable COVID-19 surveillance program at the University of Florida. We also critically discuss the successes and pitfalls of this program while also providing recommendations for the development of similar programs in the future.