bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creating Middle Ground: Transforming Outdoor Informal Learning Landscapes
Authors: Gutwill Joshua P. , Chien Hsin‐Yi , Lani Shawn , Winterheld Heike , Miller Lena , Garibay Cecilia 
Published: August 2022

AbstractIn this article, we offer a model for shifting museums away from elitism and exclusion towards inclusion and community engagement. Rather than require all learners to come to the museum, we propose installing science exhibitions and pop‐ups in urban neighborhoods. The Transforming Informal Learning Landscapes (TILL) model integrates three key components—contextually‐relevant science, learning‐centered placemaking, and content‐humanizing facilitation—to change outdoor public spaces from hallways to living rooms, places people would want to spend time, socialize and learn science. We briefly present the model and then describe our partnership that used TILL to produce and facilitate Middle Ground, a free exhibition on the social science of biases, stereotyping and prosocial behavior in a diverse outdoor urban setting. The article presents evidence of the success of Middle Ground in support of the effectiveness of the TILL model. A companion research article describes a quasi‐experimental study of the effect of facilitation on visitor learning at Middle Ground.
Amazonian Activism for European Museum Audiences: Critical Reflections on the Development of an “Amazonia” Exhibition at the National Museum of World Cultures, the Netherlands
Authors: Osorio Sunnucks Laura , Martínez Milantchi María Mercedes , Berger Martin , Scholz Andrea , Françozo Mariana 
Published: August 2022

AbstractThis paper describes and expands on the discussions held at a symposium at the Research Center for Material Culture in the Netherlands in February 2020, which was held as part of the planning of an upcoming “Amazonia” exhibition to be curated at that institution by some of the authors. The symposium invited curators and museum directors who had recently carried out projects with Amazonian communities to share their experiences with co‐production and co‐curation. The discussion and this paper aim to be a reflexive critical first step before reaching out to potential partners in South America. This paper supplements discussions on participative museology by examining the underlying frameworks of an exhibition project at its outset, in addition to contributing, as happens more commonly, post‐rationalizations in a final written evaluation. The discussion furthermore contributes to exhibition co‐curation by focusing on Amazonian‐European collaborations, which are under‐represented in Anglophone museological literature.
Spanish‐English bilingual toddlers’ vocabulary skills: The role of caregiver language input and warmth
Authors: Gámez Perla B. , Palermo Francisco , Perry Jordan S. , Galindo Maily 
Published: August 2022

AbstractThere is a well‐documented link between bilingual language development and the relative amounts of exposure to each language. Less is known about the role of quality indicators of caregiver‐child interactions in bilingual homes, including caregiver input diversity, warmth and sensitivity. This longitudinal study examines the relation between caregiver input (lexical diversity, amount), warmth and sensitivity and bilingual toddlers’ subsequent vocabulary outcomes. We video‐recorded caregiver‐child interactions in Spanish‐English Latino homes when toddlers (n = 47) were 18 months of age (M = 18.32 months; SD = 1.02 months). At the 24‐month follow‐up, we measured children's vocabulary as total vocabulary (English, Spanish combined) as well as within language (Spanish, English). Results revealed that Spanish lexical diversity exposure at 18 months from caregivers was positively associated with children's Spanish and total vocabulary scores at 24 months, while English lexical diversity was positively associated with children's English scores; lexical diversity and amount were highly correlated. Additionally, caregivers’ warmth was positively associated with children's Spanish, English and total vocabulary scores. Together, these factors accounted for substantial variance (30–40%) in vocabulary outcomes. Notably, caregiver input accounted for more variance in single language outcomes than did caregiver warmth, whereas caregiver warmth uniquely accounted for more variance in total vocabulary scores. Our findings extend prior research findings by suggesting that children's dual language development may depend on their exposure to a diverse set of words, not only amount of language exposure, as well as warm interactions with caregivers. A video abstract of this article can be viewed at https://youtu.be/q1V_7fz5wogHighlights
Video‐recorded observations of caregiver‐child interactions revealed warmth and high sensitivity from Latino caregivers.
Linguistically‐detailed analyses of caregiver input revealed wide variation in the diversity of Spanish and English directed at 18‐month‐old bilingual toddlers.
Bilingual toddlers’ vocabulary (single language, total) was positively associated with caregivers’ diverse input and warmth, thus extending prior findings on bilinguals’ amount of language exposure.
Findings suggest that caregivers’ lexical diversity explains more variance in bilingual toddlers’ single language outcomes, whereas warmth explains more variance in total vocabulary scores.
Three cases of olecranon fracture repair in the standing horse
Authors: Jimenez‐Rihuete Pablo , O'Meara Bryan 
Published: August 2022

SummaryUlnar fractures in three horses were repaired using plate fixation whilst sedated and restrained in stocks in the standing position. In each horse, the triceps muscle attachment was intact. All horses recovered well from surgery and were stable for 3 months. The plate was removed 3 months after surgery in one of the horses because of a surgical site infection. In all three cases, the fracture was adequately reduced, and the horses returned to showjumping, pleasure riding and pasture turnout with a view to begin training. The surgical technique, local anaesthesia and sedation protocols are described. This is a novel technique that may be suitable in selected cases of ulnar fracture in the horse where triceps muscle engagement is present with mild fracture displacement.
Determination of Ultra‐Trace Au, Ag, As, Pt and Re Mass Fractions in Volcanic Glasses and Rock Powders by LA‐ICP‐MS
Authors: Belgrano Thomas M. , Milton James A. , Teagle Damon A.H. 
Published: August 2022

Practical methods for determining the ultra‐trace abundances of precious metals in geological materials are needed for research into magmatic and hydrothermal processes and to expand the geochemical footprints of concealed ore deposits. This study presents a new protocol for determining Au, Ag, As, Pt and Re mass fractions in both volcanic glasses and in rock powders prepared as nano‐powder pellets, through the synthesis and refinement of published LA‐ICP‐MS methods. This matrix flexibility allows the method and its limitations to be rigorously assessed for the first time using different volcanic materials. High‐yield laser parameters, interference corrections and low oxide production rates facilitated by laser ablation sampling enabled accurate measurements without chemical pre‐separation. A key finding is that ablation‐remobilised system contamination must be quantified and corrected to make accurate ng g−1‐level Au determinations by LA‐ICP‐MS, resulting in a mean + 2s quantification limit for Au of 0.38 ng g−1. This approach is likely necessary for other ultra‐trace LA‐ICP‐MS analyses of certain elements. Following this correction, the protocol can be usefully applied to both in situ analysis of volcanic materials and efficiently integrated into methods for the determination of major and trace elements in nano‐powder pellets.
Triploid Atlantic salmon (Salmo salar) may have increased risk of primary field outbreaks of infectious salmon anaemia
Authors: Aunsmo Arnfinn , Martinsen Lisbeth , Bruheim Torkjel , Sekkelsten‐Kindt Mats Martin , Sandtrø Ane , Gaasø Solveig , Braaen Stine , Rimstad Espen 
Published: August 2022

AbstractThe impact that escaped farmed fish may have on wild populations is of major concern for Atlantic salmon (Salmo salar) farming. Triploid fish, being infertile, were originally introduced to mitigate the genetic impact of escaped fish. In the recent years, an increase in the number of infectious salmon anaemia (ISA) outbreaks in Norway has been observed, mainly in the northern parts, which is also where farming of triploid fish has been licensed. The present study investigated the susceptibility of triploid Atlantic salmon to ISA both by field observations and experimental infections. Based on field observations, we found an increased susceptibility, with 9.4 increased odds to primary ISA outbreaks in triploid fish versus diploid fish at production‐site level, and a tendency of increased odds (3.4) of ISA in triploid fish at individual cage level at sited with primary outbreaks. At some sites, ISA outbreaks were only diagnosed in cages with triploid fish and not in cages with diploid fish. Primary ISA outbreaks are the source for further spread of the disease, and it is noteworthy that in an experimental trial we found significantly more viral RNA in non‐ISA‐vaccinated triploid than in non‐ISA‐vaccinated diploid fish at the peak of the infection. Interestingly, the notable differences of susceptibility to ISA for non‐ISA vaccinated diploid and triploid fish observed in field were not repeated experimentally. The possible increased risk of ISA should be considered when evaluating the costs and benefits of triploid salmon in farming. It is recommended to keep triploid and diploid fish in biosecure separated sites, or that triploid fish are not farmed at all.
Antibioprophylaxis in endoscopic ultrasound guided fine needle aspiration in pancreatic cysts: A systematic review and meta‐analysis
Authors: Khoury Tawfik , Gincul Rodica , Mohammedi Ismael , Sbeit Wisam , Napoléon Bertrand 
Published: August 2022

AbstractAntibioprohylaxis (ABP) for pancreatic cystic lesion is still a debated clinical indication. Although professional societies guidelines still recommend ABP in endoscopic ultrasound‐fine needle aspiration (EUS‐FNA) for pancreatic cystic lesions (PCL), this standard of care recommendation was based on old and weakly planned studies with a small number of patients. Herein, in this work, we provide a critical review with pooled data analysis of the available literature. Overall, the studies reported are weak and limited with small number of patients, the absence of exact definition of infection and the heterogenicity of the type and the duration of the ABP used. Pooled data analysis showed that the effect of ABP on the rate of cyst infection was not significant (OR 0.56, 95% CI 0.17–1.2), with no significant heterogenicity between the results of the studies reviewed and reported (as assessed by Breslow Day test for homogeneity of OR's [P = 0.15]). The pooled infection rate without ABP was 0.89% and 0.36% in the ABP group. Moreover, according to the pooled data infection rate, sample size calculation demonstrated that 6954 patients are needed to show superiority of ABP, with a number needed to treat of 179 patients to prevent single infection. However, through the literature only six studies (1660 patients) reported the cyst infection rate among ABP versus control, making these results scarce and biased by a small number of patients. Therefore, we suggest the need to revise the guidelines, until performing well organized large international study to solve this controversy.
Assessment of tissue E‐cadherin and its proteolytic serum fragment in pemphigus vulgaris before and after remission: A case–control study
Authors: Youssef Randa Mohammed , Saleh Marwah Adly , Korany Mona Mostafa , Nour Zeinab A. , El‐Kalioby Mona 
Published: August 2022

AbstractBackgroundE‐cadherin is a classic cadherin that mediates keratinocyte adhesion.AimsTo assess the tissue expression of E‐cadherin and its proteolytic serum fragment (soluble E‐cadherin) in pemphigus vulgaris (PV) before and after clinical remission compared with controls.PatientsThirty‐seven PV patients and thirty controls were enrolled. Pemphigus disease area index (PDAI) was calculated for patients at baseline and after remission. Punch biopsy specimens were taken from patients before, and after remission, and from controls for assessment of tissue E‐cadherin by immunofluorescence. Similarly, serum samples were collected for assessment of serum soluble E‐cadherin by ELISA.ResultsPresence, intensity, and mean intensity of tissue E‐cadherin were significantly reduced in PV patients before treatment compared with controls (p < 0.001). Detected E‐cadherin showed mainly a basal and suprabasal distribution with cell surface and a cytoplasmic expression. Serum E‐cadherin was significantly higher in patients before treatment compared with controls (p = 0.006). With remission, tissue E‐cadherin presence, intensity, mean intensity, and serum E‐cadherin showed statistically significant improvement (p = 0.003, <0.001, <0.001, and 0.003 respectively). Tissue E‐cadherin presence and serum E‐cadherin level reached values equivalent to the controls (p = 0.49 and 0.44, respectively).ConclusionsDisruption of tissue E‐cadherin and upregulation of serum soluble E‐cadherin can contribute to the pathogenesis of PV. Clinical remission of PV is associated with normalization of tissue and serum E‐cadherin.
Impacts of polyphenols on laying hens' productivity and egg quality: A review
Authors: Abd El‐Hack Mohamed E. , Salem Heba M. , Khafaga Asmaa F. , Soliman Soliman M. , El‐Saadony Mohamed T. 
Published: August 2022

AbstractThere has been a rapid increase in the world's output of main poultry products (meat and eggs). This reflects customer desire for these high‐quality and safe products and the comparatively low price. Recently, natural feed additives, plants and products have been increasingly popular in the poultry and livestock industries to maintain and improve their health and production. Polyphenols are a type of micronutrient that is plentiful in our diet. They are phytochemicals that have health benefits, notably cardiovascular, cognitive function, antioxidant, anti‐mutagenic, anti‐inflammatory, antistress, anti‐tumour, anti‐pathogen, detoxification, growth‐promoting and immunomodulating activities. On the other hand, excessive polyphenol levels have an unclear and sometimes negative impact on gastrointestinal tract health, nutrient digestion, digestive enzyme activity, vitamin, mineral absorption, laying hens performance and egg quality. As a result, this review illuminated polyphenols' various sources, classifications, biological activities, potential usage restrictions and effects on poultry, layer productivity and egg external and internal quality.
Listeria monocytogenes two component system PieRS regulates secretion chaperones PrsA1 and PrsA2 and enhances bacterial translocation across the intestine
Authors: Cahoon Laty A. , Alejandro‐Navarreto Xiomarie , Gururaja Avinash N. , Light Sam H. , Alonzo Francis , Anderson Wayne F. , Freitag Nancy E. 
Published: August 2022

AbstractListeria monocytogenes (Lm) is a widespread environmental Gram‐positive bacterium that can transition into a pathogen following ingestion by a susceptible host. To cross host barriers and establish infection, Lm is dependent upon the regulated secretion and activity of many proteins including PrsA2, a peptidyl‐prolyl cis‐trans isomerase with foldase activity. PrsA2 contributes to the stability and activity of a number of secreted virulence factors that are required for Lm invasion, replication, and cell‐to‐cell spread within the infected host. In contrast, a second related secretion chaperone, PrsA1, has thus far no identified contributions to Lm pathogenesis. Here we describe the characterization of a two‐component signal transduction system PieRS that regulates the expression of a regulon that includes the secretion chaperones PrsA1 and PrsA2. PieRS regulated gene products are required for bacterial resistance to ethanol exposure and are important for bacterial survival during transit through the gastrointestinal tract. PrsA1 was also found to make a unique contribution to Lm survival in the GI tract, revealing for the first time a non‐overlapping requirement for both secretion chaperones PrsA1 and PrsA2 during the process of intra‐gastric infection.
Re‐imagining the ‘Taiwanese’ nation in the interpretation of the Chinese‐oriented heritage
Authors: Yao Ming‐li 
Published: August 2022

AbstractThis study aims to discuss how Chinese‐oriented heritage from Ming and Qing dynasties has been incorporated in the discourse of ‘Taiwanese’ culture to bolster the identity of Taiwan. Drawing upon the interconnected theoretical concepts of ‘imagined communities’ and ‘nationalising the past’, this study focuses on the ‘selective’ presentation of the Chinese‐oriented monuments in historic Tainan City, where the documented history of Taiwan began. This study concludes that these Chinese‐oriented monuments are represented as containing a wealth of transposable imagery, as one embodiment in the context of Taiwanese culture, and the mark of political distinction between ‘Taiwan’ and ‘China’, in the process of heritagisation. In the interpretation of heritage, this research result also suggests that the state of Republic of China (ROC) re‐invented ‘Taiwanese’ nationhood and that the state's goals of cultural establishment could be reinforced through social agents.
Double DJ‐1 domain containing Arabidopsis DJ‐1D is a robust macromolecule deglycase
Authors: Prasad Melvin , Kataria Priyanka , Ningaraju Sunayana , Buddidathi Radhika , Bankapalli Kondalarao , Swetha Chenna , Susarla Gautam , Venkatesan Radhika , D'Silva Patrick , Shivaprasad Padubidri V. 
Published: August 2022

Summary

Plants, being sessile, are prone to genotoxin‐induced macromolecule damage. Among the inevitable damaging agents are reactive carbonyls that induce glycation of DNA, RNA and proteins to result in the build‐up of advanced glycated end‐products. However, it is unclear how plants repair glycated macromolecules. DJ‐1/PARK7 members are a highly conserved family of moonlighting proteins having double domains in higher plants and single domains in other phyla.

Here we show that Arabidopsis DJ‐1D offers robust tolerance to endogenous and exogenous stresses through its ability to repair glycated DNA, RNA and proteins. DJ‐1D also reduced the formation of reactive carbonyls through its efficient methylglyoxalase activity. Strikingly, full‐length double domain‐containing DJ‐1D suppressed the formation of advanced glycated end‐products in yeast and plants.

DJ‐1D also efficiently repaired glycated nucleic acids and nucleotides in vitro and mitochondrial DNA in vivo under stress, indicating the existence of a new DNA repair pathway in plants.

We propose that multi‐stress responding plant DJ‐1 members, often present in multiple copies among plants, probably contributed to the adaptation to a variety of endogenous and exogenous stresses.
Current Occupational Perspective of Total Hip Joint Surgeons in China: A Survey of Members of the Chinese Orthopedic Association
Authors: Kong Ning , Tian Run , Cao Li , Zhou Yonggang , Wang Kunzheng , Yang Pei 
Published: August 2022

ObjectivesTo explore the basic occupational information and the preferences of surgical techniques in Chinese joint surgeons.MethodsA survey study was conducted during the Chinese Hip Society (CHS) conference of 2020. Participants from hospitals all over the country were included as the potential respondents. The questions were asked for respondents' basic information, overviews of total hip arthroplasty (THA), surgical techniques, and prosthesis selection. After data collection and filtration, analysis was conducted using chi‐square test or Fisher's exact test.ResultsOnly 8.31% of joint surgeons used robotics or navigation systems to assisted their total hip arthroplasty. For the approach preference, posterolateral approaches were generally favored, being used commonly by 75.36% of respondents while the direct anterior approach was considered the preferred choice by 8.31% of Chinese joint surgeons. 24.36% of the respondents choose to use domestic prosthesis in over 80% of their patients.ConclusionsThe intelligent THA is in the early stage at present but developing rapidly in China. The composition of surgical approach is simple at present and the continuing education should aim at increasing the diversity of approach selection in the following years. Domestic prosthesis is playing significant role in the prosthesis market. Joint registration system is urgently needed for Chinese joint surgery.
The Biochemical Mechanisms of Antimicrobial Photodynamic Therapy†
Authors: Sabino Caetano P. , Ribeiro Martha S. , Wainwright Mark , dos Anjos Carolina , Sellera Fábio P. , Dropa Milena , Nunes Nathalia B. , Brancini Guilherme T. P. , Braga Gilberto U. L. , Arana‐Chavez Victor E. , Freitas Raul O. , Lincopan Nilton , Baptista Maurício S. 
Published: August 2022

AbstractThe unbridled dissemination of multidrug‐resistant pathogens is a major threat to global health and urgently demands novel therapeutic alternatives. Antimicrobial photodynamic therapy (aPDT) has been developed as a promising approach to treat localized infections regardless of drug resistance profile or taxonomy. Even though this technique has been known for more than a century, discussions and speculations regarding the biochemical mechanisms of microbial inactivation have never reached a consensus on what is the primary cause of cell death. Since photochemically generated oxidants promote ubiquitous reactions with various biomolecules, researchers simply assumed that all cellular structures are equally damaged. In this study, biochemical, molecular, biological and advanced microscopy techniques were employed to investigate whether protein, membrane or DNA damage correlates better with dose‐dependent microbial inactivation kinetics. We showed that although mild membrane permeabilization and late DNA damage occur, no correlation with inactivation kinetics was found. On the other hand, protein degradation was analyzed by three different methods and showed a dose‐dependent trend that matches microbial inactivation kinetics. Our results provide a deeper mechanistic understanding of aPDT that can guide the scientific community toward the development of optimized photosensitizing drugs and also rationally propose synergistic combinations with antimicrobial chemotherapy.