bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experiential design on cause-related marketing: lessons from the fill-the-bottle challenge
Authors: Roederer Claire , Filser Marc 
Published: January 2022

Purpose
Based on a “Fill-the-Bottle” (FTB) challenge, this research explores how experiential design can help cause-related marketing. This study aims to show that experiences designed as anti-structural and anti-functional can raise awareness through action.

Design/methodology/approach
The authors study a corpus of 52 introspective journals and 60 pictures about the challenge, which entails filling empty bottles with cigarette butts from the streets as quickly as possible, then sharing pictures of the bottles on social media.

Findings
The anti-structural design of the experience activates the participants’ experiential system, and the social interactions between the participants and pedestrians construct meaning for the experience. The results further indicate that as follows: individuals’ frames of reference can explain whether they perceive the experience as liberatory or stochastic; anti-structural design can serve cause-related marketing by focusing on three stages: doing, showing and sharing; and experiential marketing can serve societal and social causes.

Research limitations/implications
This research involved a single field. Further research with more heterogeneous participants would be insightful. The power of experiential marketing to serve meaningful and collective causes should be encouraged. Further research should be conducted to understand and conceptualize these collective attempts to fight the dark sides of consumption.

Practical implications
In line with Pine and Gilmore’s (1999) advice to stage memorable experiences by working cautiously on cues, the FTB challenge analysis indicates that by focusing on material evidence and staging a specific sequence of doing something about it, showing everyone what is being done and expanding visibility by sharing artifacts of the action on social media, one can actually make people think about and remember the action.

Social implications
The “do-show-share” design that the FTB challenge uses can be relevant for many cause-related marketing efforts because it operates on both individual and collective levels.

Originality/value
This research offers a new perspective on experiential marketing by studying how experiences designed to be anti-structural can renew social, cause-related marketing tools.
Ghanaian SMEs’ perspective on the interrelationship between market and entrepreneurial orientations
Authors: Issau Kassimu , Soni Sanjay , Acquah Innocent Senyo Kwasi 
Published: January 2022

PurposeThis research examines the interrelationships between market orientation (MO) and entrepreneurial orientation (EO) in the small- and medium-sized enterprise (SME) sector. Due to the conflicting results associated with each orientation's influence on firm performance, some researchers advanced that scholars should resort to concurrent observation of the constructs. To the researchers, concurrent deployment of the constructs by businesses is likely to result in an enhanced performance. However, what is lacking in their proposition is how the deployment of these resources should be, thereby leading to a knowledge gap in the literature. The aforementioned gap is what this paper seeks to address.Design/methodology/approachThe study employed deductive research approach, and data were collected from 366 SMEs' owners or owner-managers of SMEs in two metropoles in Ghana. For this study, the hand delivery and collection of questionnaire technique was deployed. The reason is that most respondents may be reluctant to respond to the questionnaires through the post or Internet. Partial least square-structural equation modelling (PLS-SEM) was employed for the data analysis due to its importance in allowing the testing of relationships among constructs. Furthermore, seven-point Likert scale was used to generate responses from the respondents.FindingsThe result indicates that MO and EO have a positive and significant influence on each other. However, the influence of EO on MO is greater. Therefore, when owners of SMEs are embracing the two constructs in their businesses, EO should precede MO. The finding is a novelty of this study. Through this result, the owners of SMEs would have knowledge of embracing EO before MO during the employment of the two constructs in their firms. The study further revealed that not all the components of MO have positive and significant influence on EO, and the reverse is true. Without this study, the owners of SMEs would have placed equal attention on each construct and their components. The study also indicates that deployment of MO in its composite form rather than components is the best way for improving EO.Practical implicationsThe more SMEs engage in MO activities, the likelihood of an increase in their entrepreneurial spirit and the opposite is true. However, engaging in more EO activities would result in higher MO than the reverse.Originality/valueThe findings add to the empirical literature by revealing the interrelationships between MO and EO, which serve as a guide to owners of SMEs and practitioners in their concurrent deployment of the two constructs. The findings would also open replication doors for future researchers in different settings.
Hybrid working can help recruit and retain talent, upskill leaders and boost team working, suggests a case study from an international professional services firm
Authors: Summerfield Richard 
Published: January 2022

Purpose
This paper sets out the three-year people strategy at the core of a traditional professional services firm’s ambitious plans to transform into a progressive, agile and fast-growing business. The lynchpin of its acquisitions-led and people-centred cultural transformation programme is Project Zander, a pioneering hybrid working experience in its Jersey office that can be adapted to different geographic locations as the business expands.

Design/methodology/approach
Individual-level information gathered from the firm.

Findings
Nesting a hybrid working model within a clearly articulated people strategy aligned with corporate values appears to be setting the business well on the way to achieving its ambitions. Key is the ability of leaders to plan ahead for the future, mapping out a three-year journey with important milestones along the way. Although it is still early days, the business is already seeing a positive impact on collaboration, team working, staff recruitment and retention, leadership development, empowerment and creativity, employee engagement, and rebuilding the confidence of young people, many of whom have been negatively impacted by COVID-19 lockdowns.

Originality/value
The strategy has an innovative hybrid working approach as its cornerstone
Bacterial volatile organic compounds induce adverse ultrastructural changes and DNA damage to the sugarcane pathogenic fungus Thielaviopsis ethacetica
Authors: Freitas Carla Sant Anna , Maciel Lucas Ferreira , Corrêa dos Santos Renato Augusto , Costa Ohanna Maria Menezes Madeiro , Maia Francisco Carlos Barbosa , Rabelo Renata Santos , Franco Henrique Coutinho Junqueira , Alves Eduardo , Consonni Sílvio Roberto , Freitas Raul Oliveira , Persinoti Gabriela Felix , Oliveira Juliana Velasco de Castro 
Published: January 2022

SummaryDue to an increasing demand for sustainable agricultural practices, the adoption of microbial volatile organic compounds (VOCs) as antagonists against phytopathogens has emerged as an eco‐friendly alternative to the use of agrochemicals. Here, we identified three Pseudomonas strains that were able to inhibit, in vitro, up to 80% of mycelial growth of the phytopathogenic fungus Thielaviopsis ethacetica, the causal agent of pineapple sett rot disease in sugarcane. Using GC/MS, we found that these bacteria produced 62 different VOCs, and further functional validation revealed compounds with high antagonistic activity to T. ethacetica. Transcriptomic analysis of the fungal response to VOCs indicated that these metabolites downregulated genes related to fungal central metabolism, such as those involved in carbohydrate metabolism. Interestingly, genes related to the DNA damage response were upregulated, and micro‐FTIR analysis corroborated our hypothesis that VOCs triggered DNA damage. Electron microscopy analysis showed critical morphological changes in mycelia treated with VOCs. Altogether, these results indicated that VOCs hampered fungal growth and could lead to cell death. This study represents the first demonstration of the molecular mechanisms involved in the antagonism of sugarcane phytopathogens by VOCs and reinforces that VOCs can be a sustainable alternative for use in phytopathogen biocontrol.
An analysis of protists in Pacific oxygen deficient zones: implications for Prochlorococcus and N2‐producing bacteria
Authors: Fuchsman Clara A. , Cherubini Luca , Hays Matthew D. 
Published: January 2022

SummaryOcean oxygen deficient zones (ODZs) host 30%–50% of marine N2 production. Cyanobacteria photosynthesizing in the ODZ create a secondary chlorophyll maximum and provide organic matter to N2‐producing bacteria. This chlorophyll maximum is thought to occur due to reduced grazing in anoxic waters. We first examine ODZ protists with long amplicon reads. We then use non‐primer‐based methods to examine the composition and relative abundance of protists in metagenomes from the Eastern Tropical North and South Pacific ODZs and compare these data to the oxic Hawaii Ocean Time‐series (HOT) in the North Pacific. We identify and quantify protists in proportion to the total microbial community. From metagenomic data, we see a large drop in abundance of fungi and protists such as choanoflagellates, radiolarians, cercozoa and ciliates in the ODZs but not in the oxic mesopelagic at HOT. Diplonemid euglenozoa were the only protists that increased in the ODZ. Dinoflagellates and foraminifera reads were also present in the ODZ though less abundant compared to oxic waters. Denitrification has been found in foraminifera but not yet in dinoflagellates. DNA techniques cannot separate dinoflagellate cells and cysts. Metagenomic analysis found taxonomic groups missed by amplicon sequencing and identified trends in abundance.
‘The rainha is the boss!’: On Masculinities, Time and Precolonial Women of Authority in Northern Mozambique
Authors: Katto Jonna 
Published: January 2022

ABSTRACTThis article focuses on the oral historical narratives about precolonial women of authority (or rainhas in Portuguese) to explore the deeper history of gendered power in northern Mozambique. History‐telling is a gendered practice, and nowadays male elders are usually the ones most knowledgeable in these narratives. Moreover, telling these tales ‐ which in interview situations involves personal interpretations and comments ‐ the men also story gendered temporal worlds. This article looks more closely at two seemingly clashing (and incompatible) storylines that emerge in the oral history material. One tells of women's spiritual‐political power in the Yaawo chieftaincies in precolonial times, while the other tells a narrative of masculinised power and woman's subordinate position in relation to male leaders. The article focus's especially on how the male narrators talk about masculinity and how different models of masculinity in turn shape the historical narratives they tell. As the author's analysis demonstrates, these models have different temporal origins; yet they intertwine in present time‐space, interacting also with newer notions (e.g. the ‘new man’ of the socialist period). The article thus shows how various models of masculinity linked to different temporalities and different imaginings of the relationality between femininity and masculinity coexist and shape male gendered identities as well as the histories men tell about the past and gendered power.
State of the Field: Physical Culture
Authors: Heffernan Connor 
Published: January 2022

AbstractThis article surveys the state of the field of physical culture within the discipline of history. Understood broadly as a society's interest in gymnasium and health cultures, physical culture has become a topic of increasing importance for historians, sociologists and performance scholars in the past two decades. Seen as a distinct field from sport history, works on physical culture have evolved from sporadic and one‐off studies to nuanced discussions about the idealised body and its broader social message. As such, studies of physical culture have become excellent platforms for the often implicit ways in which body types have been used in discussions of race, nationalism, class, gender and medicine. Although studies of physical culture began over a century ago, the field has only recently begun to enjoy scholarly attention and, thereby, evolve.
Association of tumor necrosis factor‐α inhibitors and liver cirrhosis in patients with rheumatoid arthritis: A nationwide population‐based nested case‐control study
Authors: Chen Der‐Yuan , Lin Ching‐Heng , Chen Hsin‐Hua , Tang Kuo‐Tung 
Published: January 2022

AbstractAimResults from various studies are controversial regarding long‐term hepatic effects of tumor necrosis factor (TNF)‐α inhibitors. Here we aimed to investigate the development of liver cirrhosis with TNF‐α inhibitors use in patients with rheumatoid arthritis (RA).MethodThis nested case‐control study was based on the National Health Insurance Research Database (January 1, 2000 to December 31, 2008) of Taiwan. We identified 559 adult RA patients who developed liver cirrhosis, and 1055 matched control RA patients. TNF‐α inhibitors of interest in the study period included adalimumab and etanercept. Multivariate logistic regression analysis for the development of liver cirrhosis with respect to use of TNF‐α inhibitors was performed.ResultsThe incidence rate of liver cirrhosis was 274 per 100 000 person‐years in newly diagnosed RA patients. We found the use of TNF‐α inhibitors was not associated with the development of liver cirrhosis in RA patients (odds ratio 1.02, 95% confidence interval 0.61, 1.70) after adjustment for potential confounders. In addition, the finding was robust to an unobserved confounder.ConclusionWe found no association between the use of TNF‐α inhibitors and development of liver cirrhosis in RA patients.
Efficacy and safety of EBUS‐TBNA under conscious sedation with meperidine and midazolam
Authors: Piro Roberto , Casalini Eleonora , Fontana Matteo , Galeone Carla , Ruggiero Patrizia , Taddei Sofia , Ghidoni Giulia , Patricelli Giulia , Facciolongo Nicola 
Published: January 2022

AbstractBackgroundAccording to the guidelines, endobronchial ultrasound guided transbronchial needle aspiration (EBUS‐TBNA) is the technique of choice for the diagnosis of mediastinal involvement in lung cancer; it is also useful for other mediastinal malignancies and benign pathology. Nevertheless, there is still discussion about whether to perform it under general anesthesia or under conscious sedation.MethodsWe retrospectively analyzed the data of all patients who underwent EBUS‐TBNA under conscious sedation with up to 1 mg/kg of meperidine and up to 0.15 mg/kg of midazolam in the Interventional Pulmonology Unit of the Azienda USL‐IRCCS Santa Maria Nuova of Reggio Emilia during 2 consecutive years. Demographic data, indication for the procedure, duration, number of lymph node sampled, number of passes per station, diagnostic yield, drugs dosage, questionnaire score, and complications were collected.ResultsA total of 302 patients underwent EBUS‐TBNA, and 68% of the patients were males and the mean age was 65 ± 13 years old. The average duration of procedures was 24.4 minutes and the mean dosage of drugs was 4.32 ± 1.52 mg for midazolam and 50.86 ± 13.71 mg for meperidine. The mean number of lymph nodes sampled per patient was 1.75 ± 0.82, and each patient received an average of 4.71 ± 1.78 passes. A total of 90.7% of patients completed the procedures, 85% had adequate samples, and 94.4% of patients declared with Likert's questionnaire that they strongly agree to repeat the test if necessary.ConclusionEBUS‐TBNA performed under conscious sedation with meperidine and midazolam is feasible and well‐tolerated and has a similar diagnostic yield of that reported in literature.
Host genetics determines food preferences of the moth Perzelia arda (Lepidoptera: Depressariidae)
Authors: Pietrantuono Ana Laura , Pastorino Mario J. , Fernández‐Arhex Valeria , Corley Juan Carlos , Marchelli Paula 
Published: January 2022

Abstract
Genetic variation among host plants can influence herbivore behaviour and consequently their abundance, performance and environmental impact. In the Andean‐Patagonian forest, the arboreal vegetation is dominated by species of genus Nothofagus. Previous studies of Nothofagus alpina demonstrated differences in genetic diversity among and within its populations. The native caterpillar Perzelia arda feeds on various Nothofagus sp.
Our aim was to evaluate host selection behaviour of P. arda larvae towards different genetic pools of N. alpina trees.
We collected leaf samples from trees growing in a common garden field trial and evaluated, by paired comparisons, not only differences among provenances but also variation between and within open pollinated families.
Our results demonstrated that P. arda performed a choice between the leaves of the host plants offered. This larva was able to choose specific provenances, open pollinated families and genotypes of N. alpina.
In conclusion, the larva is guided by characteristics of individuals and host plant species. These innovative results in insect–plant interaction studies demonstrate that it is important to evaluate discrimination between intra‐specific hosts. Further study is required to fully understand the use of resources by this native insect, as well as the ecological consequences.
Market and welfare effects of quality misperception in food labels
Authors: Scott Francisco , Sesmero Juan P. 
Published: January 2022

AbstractInformation‐based policies, most prominently labels, reveal credence attributes of food products and, presumably, help consumers make better choices by reducing their misperception of product quality. However, much remains unexamined regarding how firms' strategic reactions to consumers' misperception of quality influence the benefits of information‐based policies. We consider an oligopoly model where heterogeneous consumers can over‐ or underestimate the quality of products in the market, and firms choose quality and prices conditional on consumers' perception of quality. We find that, under empirically prevalent conditions, misperception can increase efficiency in relation to the perfect information case; it does so if (1) it strengthens firms' incentives to provide higher quality, countervailing the chronic underprovision of quality that prevails under perfect information, or (2) it galvanizes competition, reversing another deleterious effect of product differentiation, namely high quality‐adjusted markups that restrain commerce. Our results imply that information‐based policies aimed at curbing misperception, such as requiring or allowing (under voluntary certification) additional information, nudging, and changes in label format, can have deleterious effects on efficiency and, perhaps more importantly, hurt the very consumers they mean to protect.
Regulation of heart rate in vertebrates during hypoxia: A comparative overview
Authors: Joyce William , Wang Tobias 
Published: January 2022

AbstractAcute exposure to low oxygen (hypoxia) places conflicting demands on the heart. Whilst an increase in heart rate (tachycardia) may compensate systemic oxygen delivery as arterial oxygenation falls, the heart itself is an energetically expensive organ that may benefit from slowing (bradycardia) to reduce work when oxygen is limited. Both strategies are apparent in vertebrates, with tetrapods (mammals, birds, reptiles, and amphibians) classically exhibiting hypoxic tachycardia and fishes displaying characteristic hypoxic bradycardia. With a richer understanding of the ontogeny and evolution of the responses, however, we see similarities in the underlying mechanisms between vertebrate groups. For example, in adult mammals, primary bradycardia results from the hypoxic stimulation of carotid body chemoreceptors that are overwhelmed by mechano‐sensory feedback from the lung associated with hyperpnoea. Fish‐like bradycardia prevails in the mammalian foetus (which, at this stage, is incapable of pulmonary ventilation), and in fish and foetus alike, the bradycardia ensues despite an elevation of circulating catecholamines. In both cases, the reduced heart rate may primarily serve to protect the heart. Thus, the comparative perspective offers fundamental insight into how and why different vertebrates regulate heart rate in different ways during periods of hypoxia.
Galectin‐3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling
Authors: Cheng Wan‐Li , Chen Yao‐Chang , Li Shao‐Jung , Lee Ting‐I , Lee Ting‐Wei , Higa Satoshi , Chung Cheng‐Chih , Kao Yu‐Hsun , Chen Shih‐Ann , Chen Yi‐Jen 
Published: January 2022

AbstractAimGalectin‐3 (Gal‐3) is a biomarker of atrial fibrillation (AF) that mediates atrial inflammation. CD98 is the membrane surface receptor for Gal‐3. Nevertheless, the role of the Gal‐3/CD98 axis in atrial arrhythmogenesis is unclear. In this study, we investigated the effects of Gal‐3/CD98 signalling on atrial pathogenesis.MethodsWhole cell patch clamp and western blotting were used to analyse calcium/potassium homeostasis and calcium‐related signalling in Gal‐3‐administrated HL‐1 atrial cardiomyocytes with/without CD98 neutralized antibodies. Telemetry electrocardiographic recording, Masson's trichrome staining and immunohistochemistry staining of atrium were obtained from mice having received tail‐vein injections with Gal‐3.ResultsGal‐3‐treated HL‐1 myocytes had a shorter action potential duration, smaller L‐type calcium current, increased sarcoplasmic reticulum (SR) calcium content, Na+/Ca2+ exchanger (NCX) current, transient outward potassium current, and ultrarapid delayed rectifier potassium current than control cells had. Gal‐3‐treated HL‐1 myocytes had greater levels of SR Ca2+ATPase, NCX, Nav1.5, and NLR family pyrin domain containing 3 (NLRP3) expression and increased calcium/calmodulin‐dependent protein kinase II (CaMKII), ryanodine receptor 2 (RyR2), and nuclear factor kappa B (NF‐κB) phosphorylation than control cells had. Gal‐3‐mediated activation of CaMKII/RyR2 pathway was diminished in the cotreatment of anti‐CD98 antibodies. Mice that were injected with Gal‐3 had more atrial ectopic beats, increased atrial fibrosis, and activated NF‐κB/NLRP3 signalling than did control mice (nonspecific immunoglobulin) or mice treated with Gal‐3 and anti‐CD98 antibodies.ConclusionGal‐3 recombinant protein administration increases atrial fibrosis and arrhythmogenesis through CD98 signalling. Targeting Gal‐3/CD98 axis might be a novel therapeutic strategy for patients with AF and high Gal‐3 levels.