bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Fibrotic Liver Regeneration After Partial Hepatectomy With Intravoxel Incoherent Motion Diffusion-Weighted Imaging: An Experimental Study in a Rat Model With Carbon Tetrachloride Induced Liver Injury
Authors: Xie Shuangshuang , Qiu Caixin , Sun Yajie , Yu Yongquan , Hu Zhandong , Zhang Kun , Chen Lihua , Cheng Yue , Bao Mingzhu , Zhang Quansheng , Zhu Jinxia , Grimm Robert , Shen Wen 
Published: February 2022

PurposeTo determine whether intravoxel incoherent motion (IVIM) parameters correlate with liver regeneration and function recovery after partial hepatectomy (PH) in rats with carbon tetrachloride (CCl4)-induced liver fibrosis.MethodsSixty-two adult Sprague-Dawley rats were divided into the control group and the fibrosis group with CCl4 injection for 8 weeks. At the end of the 8th week, all rats received left lateral lobe liver resection. Within each group, IVIM imaging (n = 10/group) and histologic and biochemical analyses (n = 3/group/time point) were performed pre- and post-PH (on days 1, 2, 3, 5, 7, 14, and 21). Differences in liver IVIM parameters and correlation between IVIM parameters and Ki-67 indices, hepatocyte diameter, alanine transaminase (ALT), aspartate aminotransferase (AST), and total bilirubin (TBil) values were analyzed.ResultsPost-PH, liver true diffusion coefficient (D) values decreased and pseudodiffusion coefficient (D*) and perfusion fraction (PF) values increased, then recovered to pre-PH levels gradually in both fibrosis and control rats. PF in fibrosis group were significantly higher than in controls from 3 to 21 days (P &lt; 0.05). In fibrosis rats, both Ki-67 indices and hepatocyte diameters increased, and a strong correlation was found between PF and Ki-67 indices (r = −0.756; P = 0.03), D* and PF values and ALT, AST, and TBil values (r = −0.762 to −0.905; P &lt; 0.05). In control rats, only hepatocyte diameters increased, and all IVIM parameters correlated well with hepatocyte diameters, ALT, AST and TBil values (r = 0.810 to −1.000; P &lt; 0.05).ConclusionThe regeneration pattern in fibrotic liver tissue was different compared with control livers. IVIM parameters can monitor liver regeneration and functional recovery non-invasively after PH.
MEMS GC Column Performance for Analyzing Organics and Biological Molecules for Future Landed Planetary Missions
Authors: Blase Ryan C. , Libardoni Mark J. , Miller Gregory P. , Miller Kelly E. , Phillips-Lander Charity M. , Glein Christopher R. , Waite J. Hunter , Ghosh Abhishek , Venkatasubramanian Anandram , Li Maxwell Wei-hao , Stephens Andrew , Fan Xudong , Kurabayashi Katsuo 
Published: February 2022

We present a novel, innovative approach to gas chromatography-mass spectrometry (GC-MS) based on micro-electro-mechanical systems (MEMS) columns that improve the current, state-of-the-art by dramatically reducing the size, mass, and power resources for deploying GC for future landed missions. The outlet of the MEMS GC column was coupled to a prototype of the MAss Spectrometer for Planetary EXploration (MASPEX) through a heated transfer line into the ion source. MEMS GC-MS experiments were performed to demonstrate linearity of response and establish limit of detection (LOD) to alkanes (organics), fatty acid methyl esters (FAMEs) and chemically derivatized amino acids (biological molecules). Linearity of response to each chemical family was demonstrated over two orders of magnitude dynamic range and limit of detection (LOD) values were single to tens (4–43) of picomoles per 1 μl injection volume. MEMS GC column analytical performance was also demonstrated for a “Mega Mix” of chemical analytes including organics and biological molecules. Chromatographic resolution exceeded 200, retention time reproducibility was &lt;&lt; 1% RSD (majority ≤ 0.3%), and peak capacity values calculated to be 124 ± 2 over a 435 s retention time window. The 5.5 m MEMS column was also shown to be a suitable alternative to traditional commercial columns for use in comprehensive two-dimensional gas chromatography (GC × GC). Mass spectra collected from MASPEX showed close consistency with National Institute of Technology (NIST) reference mass spectra and were used for high confidence identification of all eluting analytes.
Blood Urea Nitrogen-to-Albumin Ratio in Predicting Long-Term Mortality in Patients Following Coronary Artery Bypass Grafting: An Analysis of the MIMIC-III Database
Authors: Zhao Diming , Chen Shanghao , Liu Yilin , Xu Zhenqiang , Shen Hechen , Zhang Shijie , Li Yi , Zhang Haizhou , Zou Chengwei , Ma Xiaochun 
Published: February 2022

BackgroundThis study examined the role of blood urea nitrogen-to-albumin ratio (BAR) in predicting long-term mortality in patients undergoing coronary artery bypass grafting (CABG).MethodsIn this retrospective cohort study, patients undergoing CABG were enrolled from the Medical Information Mart for Intensive Care III (MIMIC III) database. Patients were divided into the three groups according to the optimal cutoff values of BAR determined by X-tile software. The survival curve was constructed by the Kaplan–Meier method and multivariate Cox regression analysis was performed to explore the independent prognostic factors of 1- and 4-year mortality after CABG. The receiver operating characteristic (ROC) curves and the areas under the ROC curves (AUCs) were calculated to estimate the accuracy of BAR in predicting the outcomes. Subgroup analyses were also carried out.ResultsA total of 1,462 patients at 4-year follow-up were included, of which 933, 293, and 236 patients were categorized into the group 1 (≤ 6.45 mg/g), group 2 (&gt;6.45 and ≤ 10.23 mg/g), and group 3 (&gt;10.23 mg/g), respectively. Non-survivors showed an increased level of BAR at both 1- (p &lt; 0.001) and 4-year (p &lt; 0.001) follow-up compared with the survivors. The patients with a higher BAR had a higher risk of 1- and 4-year mortality following CABG (33.05 vs. 14.33 vs. 5.14%, p &lt; 0.001 and 52.97 vs. 30.72 vs. 13.08%, p &lt; 0.001, respectively). Cox proportional hazards regression model suggested a higher BAR as an independent risk factor of 1-year mortality (HR 3.904; 95% CI 2.559–5.956; P &lt; 0.001) and 4-year mortality (HR 2.895; 95% CI 2.138–3.921; P &lt; 0.001) after adjusting for confounders. Besides, the receiver operating characteristic (ROC) curves showed the better predictive ability of BAR compared to other grading scores at both 1- (0.7383, 95% CI: 0.6966–0.7800) and 4-year mortality (0.7189, 95% CI: 0.6872–0.7506). Subgroup analysis demonstrated no heterogeneous results of BAR in 4-year mortality in particular groups of patient.ConclusionThis report provided evidence of an independent association between 1- and 4-year mortality after CABG and BAR. A higher BAR was associated with a higher risk of long-term mortality and could serve as a prognostic predictor in patients following CABG.
Non-intubated Thoracoscopic Surgery to Minimize Contamination From Airway Secretions During the COVID-19 Pandemic
Authors: Wang Man-Ling , Hung Ming-Hui , Hsu Hsao-Hsun , Cheng Ya-Jung , Chen Jin-Shing 
Published: February 2022

BackgroundGeneral anesthesia and tracheal intubation potentially pose a high risk to health care workers (HCWs) managing surgical patients during the coronavirus disease 2019 (COVID-19) pandemic. Non-intubated anesthesia is a rational way of managing patients undergoing thoracoscopic surgery that avoids tracheal intubation and minimizes the aerosols generated during airway instrumentation. The purpose of this study was to determine whether non-intubated anesthesia in combination with a face mask is safe and feasible in patients undergoing thoracoscopic surgery.MethodsA total of 18 patients who underwent non-intubated thoracoscopic surgery with a face mask during the perioperative period between March 9, 2020 and April 6, 2020 were included. The main outcomes were anesthetic management and postoperative results.ResultsThe 18 patients had a mean age of 64 years and a body mass index of 22.9 kg/m2. All patients wore a mask during induction of anesthesia and throughout surgery. Three patients underwent lobectomy, four segmentectomy, ten wedge resection, and one underwent anterior mediastinal tumor resection. No patient developed cough or vomiting during the perioperative period. All patients were transferred to the postoperative recovery unit within 15 min of the end of surgery (average 7.2 min). No patient required conversion to tracheal intubation or conversion to thoracotomy.ConclusionNon-intubated anesthesia with a mask was safe and feasible in patients undergoing thoracoscopic surgery. Avoidance of intubated general anesthesia and use of a lung separation device may reduce the risk to HCWs of contamination by airway secretions, thereby conserving personal protective equipment, especially during the COVID-19 pandemic.
COVID-19 and Postural Control—A Stabilographic Study Using Rambling-Trembling Decomposition Method
Authors: Żychowska Magdalena , Jaworecka Kamila , Mazur Ewelina , Słomka Kajetan , Marszałek Wojciech , Rzepko Marian , Czarny Wojciech , Reich Adam 
Published: February 2022

Background and Objectives: Some respiratory viruses demonstrate neurotropic capacities. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently taken over the globe, causing coronavirus disease 2019 (COVID-19). The aim of the study was to evaluate the impact of COVID-19 on postural control in subjects who have recently recovered from the infection. Materials and Methods: Thirty-three convalescents who underwent COVID-19 within the preceding 2–4 weeks, and 35 healthy controls were enrolled. The ground reaction forces were registered with the use of a force platform during quiet standing. The analysis of the resultant center of foot pressure (COP) decomposed into rambling (RAMB) and trembling (TREMB) and sample entropy was conducted. Results: Range of TREMB was significantly increased in subjects who experienced anosmia/hyposmia during COVID-19 when the measurement was performed with closed eyes (p = 0.03). In addition, subjects who reported dyspnea during COVID-19 demonstrated significant increase of length and velocity of COP (p < 0.001), RAMB (p < 0.001), and TREMB (p < 0.001), indicating substantial changes in postural control. Conclusions: Subjects who had experienced olfactory dysfunction or respiratory distress during COVID-19 demonstrate symptoms of balance deficits after COVID-19 recovery, and the analysis using rambling-trembling decomposition method might point at less efficient peripheral control. Monitoring for neurological sequelae of COVID-19 should be considered.
Synthesis, Characterization, Biological Evaluation and DNA Interaction Studies of 4-Aminophenol Derivatives: Theoretical and Experimental Approach
Authors: Rafique Bushra , Kalsoom Saima , Sajini Abdulrahim A. , Ismail Hammad , Iqbal Mudassir 
Published: February 2022

In the present study, five 4-aminophenol derivatives (4-chloro-2-(((4-hydroxyphenyl)imino)methyl)phenol(S-1), 4-((4-(dimethylamino)benzylidene)amino)phenol(S-2), 4-((3-nitrobenzylidene)amino)phenol(S-3), 4-((thiophen-2-ylmethylene)amino)phenol(S-4) and 4-(((E)-3-phenylallylidene)amino)phenol(S-5)) were synthesized and characterized by FT-IR, 1H-NMR, 13C-NMR and elemental analyses. The synthesized compounds were tested for their antimicrobial (Gram-positive and Gram-negative bacteria and Saccharomyces cervesea fungus) and antidiabetic (α-amylase and α-glucosidase inhibitory) activities. All the compounds showed broad-spectrum activities against the Staphylococcus aureus (ATCC 6538), Micrococcus luteus (ATCC 4698), Staphylococcus epidermidis (ATCC 12228), Bacillus subtilis sub. sp spizizenii (ATCC 6633), Bordetella bronchiseptica (ATCC 4617) and Saccharomyces cerevisiae (ATCC 9763) strains. The newly synthesized compounds showed a significant inhibition of amylase (93.2%) and glucosidase (73.7%) in a concentration-dependent manner. Interaction studies of Human DNA with the synthesized Schiff bases were also performed. The spectral bands of S-1, S-2, S-3 and S-5 all showed hyperchromism, whereas the spectral band of S-4 showed a hypochromic effect. Moreover, the spectral bands of the S-2, S-3 and S-4 compounds were also found to exhibit a bathochromic shift (red shift). The present studies delineate broad-spectrum antimicrobial and antidiabetic activities of the synthesized compounds. Additionally, DNA interaction studies highlight the potential of synthetic compounds as anticancer agents. The DNA interaction studies, as well as the antidiabetic activities articulated by the molecular docking methods, showed the promising aspects of synthetic compounds.
Pensar la violencia institucional desde un enfoque de género, diversidad y derechos humanos:
Authors: Manestar Malka Soledad 
Published: February 2022

El artículo busca avanzar en la producción de conocimiento sobre las violencias estatales, profundizando y complejizando el análisis de la violencia institucional desde un enfoque de género, diversidad y derechos humanos, a partir del estudio de un caso de violencia policial producido en contra de una joven trans durante el ASPO en la provincia de Jujuy. Se considerarán especialmente las condiciones sistemáticas y estructurales de discriminación y violencia que atraviesan el colectivo de mujeres travestis, transexuales y transgénero, como consecuencia de prejuicios y estereotipos que responden a una concepción cisbinaria de la sociedad y que constituyen obstáculos para el acceso igualitario a los derechos, derivados de la falta de implementación de políticas públicas y de barreras concretas en el acceso a la justicia. En este sentido, repensar las categorías desde las que se analiza la violencia institucional constituye una estrategia capaz de avanzar hacia la inclusión en dignidad y derechos del colectivo de mujeres trans, entendiendo que no basta con respetar las diferencias, sino que es necesario avanzar hacia una democracia plural, diversa e inclusiva que reconozca y garantice ciudadanía en términos de igualdad y no discriminación a todas las personas.
Actuación de las Fuerzas de Seguridad durante aislamiento social, preventivo y obligatorio en la Provincia de Córdoba
Authors: Plaza Schaefer Valeria , Sanchez Delia M. 
Published: February 2022

Desde el Programa de Extensión “Seguridad y Derechos Humanos” de la Facultad de Ciencias Sociales (FCS) de la Universidad Nacional de Córdoba (UNC) realizamos un relevamiento de casos sobre prácticas abusivas por parte de las fuerzas de seguridad en el marco de las detenciones y controles establecidos para garantizar el aislamiento social y obligatorio en Provincia de Córdoba. Nos propusimos comprender las condiciones, situaciones y actores que habilitan las mismas; como así también generar instancias de difusión con organizaciones sociales y la comunidad universitaria, y de articulación con los actores estatales para aportar al diseño de políticas preventivas. En el presente trabajo caracterizamos, por un lado, el proceso de registro realizado en el primer momento de la pandemia: las acciones y estrategias de visibilización y articulaciones emprendidas. Y, por otro lado, planteamos algunas cuestiones conceptuales y metodológicas en relación a las estrategias de trabajo conjunto con organizaciones sociales para el registro y sistematización de las prácticas de violencia institucional en el contexto de pandemia/ post pandemia.
PengaruhUsia dan Insentif terhadap Kinerja Kader Posyandu di Kabupaten Purworejo
Authors: Zuliyanti Nurma Ika , Hidayati Ulfah 
Published: February 2022

Cadre is one part of the community where voluntarily in the implementation of the posyandu. the success of posyandu in improving the health of mothers, infants, toddlers, and EFA is influenced by the performance of cadres. The purpose of this study is to determine the effect of age and incentives on the performance of cadres. The study was conducted on 200 cadres in 25 posyandu in Purworejo Regency and was selected using simple random sampling. This type of research uses observational analytics using cross-sectional techniques. The independent variables are age and incentives. The dependent variable is the performance of cadres. Collecting data using a questionnaire. Data processing used the chi square test with SPSS version 21 application. The results showed that there was a significant effect of age on the performance of cadres with the possibility of performing well 3.35 times. There is a significant effect of getting incentives on the performance of cadres with the possibility of performing well 2.09 times. Abstrak Kader salah satu bagian dari masyarakat dimana secara sukarela dalam penyelenggaraan posyandu. keberhasilan posyandu dalam peningkatan kesehatan ibu, bayi, balita, dan PUS dipengaruhi oleh kinerja kader. Tujuan dalam penelitian ini agar diketahuinya pengaruh usia dan insentif terhadap kinerja kader. Penelitian dilakukan pada 200 kader yang berada di 25 posyandu di Kabupaten Purworejo dan dipilih menggunakan simple random sampling. Jenis penelitian menggunakan analitik observasional menggunakan teknik potong lintang. Variabel bebas adalah usia dan insentif. Variabel terikat adalah kinerja kader. Pengumpulan data menggunakan kuesioner. Pengolahan data menggunakan uji chi-square dengan aplikasi SPSS versi 21. Hasil penelitian menunjukan terdapat pengaruh yang signifikan usia terhadap kinerja kader dengan kemungkinan berkinerja baik 3.35 kali. Terdapat pengaruh yang signifikan mendapatkan insentif terhadap kinerja kader dengan kemungkinan berkinerja baik 2.09 kali.
Gambaran Pola Asuh Pada Balita Underweight dan Diare di Kota Salatiga
Authors: Rida Nova , Brigitte Sarah Renyoet  , Fiane de Fretes  
Published: February 2022

Toddlers are one of the vulnerable groups in the community who are prone to health and nutrition problems. Toddlers with nutritional problems cause a weakened immune system, making them susceptible to infectious diseases such as diarrhea. Fulfilling the nutritional needs of toddlers which are included in parental care, good parenting factors can prevent children from diarrhea so that children's growth and development can be optimal. The purpose of this study was to describe the parenting pattern of underweight and diarrheal toddlers in Salatiga City. This research method uses descriptive analytic with cross sectional research design. This study will be conducted in 4 sub-districts in Salatiga such as Sidorejo, Sidomukti, Argomulyo and Tingkir. The population in this study were mothers who had children aged 24-59 months in Salatiga, with 72 respondents underweight and diarrhea. The results showed that the factors of complementary feeding, psychosocial stimulation, hygiene practices and environmental sanitation, as well as the care of sick children and the pattern of seeking health services had good parenting patterns as indicated by the respondents' answers, except for the factor of exclusive breastfeeding. categorized as adequate parenting. The conclusion of this study is that most of the respondents in Salatiga City who took part in this study had good parenting patterns, based on the respondents who answered correctly.

ABSTRAK
Balita merupakan salah satu kelompok rawan dalam kelompok masyarakat yang rawan mengalami masalah kesehatan dan gizi. Balita dengan masalah gizi menyebabkan menurunnya sistem kekebalan tubuh, sehingga rentan terkena penyakit infeksi seperti diare. Pemenuhan kebutuhan gizi pada masa balita yang termasuk dalam pengasuhan orang tua, faktor pola asuh yang baik dapat mencegah anak diare sehingga pertumbuhan dan perkembangan anak dapat optimal. Tujuan dari penelitian ini adalah untuk menggambarkan pola asuh pada balita underweight dan diare di Kota Salatiga. Metode penelitian ini menggunakan deskriptif analitik dengan desain penelitian cross sectional. Studi ini akan dilakukan di 4 kecamatan di Salatiga seperti Sidorejo, Sidomukti, Argomulyo dan Tingkir. Populasi dalam penelitian ini adalah ibu yang memiliki anak berusia 24-59 bulan di Salatiga, dengan jumlah responden 72 balita underweight dan diare. Hasil penelitian menunjukkan pada faktor pemberian makanan pendamping ASI, rangsangan psikososial, praktek kebersihan (hygiene) dan sanitasi lingkungan, serta perawatan anak dalam keadaan sakit dan pola pencarian pelayanan kesehatan memiliki pola asuh yang baik yang ditunjukan dari jawaban responden, kecuali pada faktor pemberian ASI eksklusif yang dikategorikan pola asuh cukup. Kesimpulan dari penelitian ini adalah sebagaian besar responden di Kota Salatiga yang mengikuti penelitian ini memiliki pola asuh baik, berdasarkan responden menjawab dengan benar.
Hubungan Sarapan, Status Gizi Dengan Konsentrasi Belajar Mahasiswa Di STIKes PERTAMEDIKA Jakarta
Authors: Dwi Dwi Ayu Lestari , Falah Falah Indriawati Barokah , Putri Sahari  
Published: February 2022

The success of the learning process is influenced by the ability to concentrate on the object being studied. concentration is an important aspect for successful learning, breakfast for students is very important because students need energy for learning activities. Therefore, learning can learn because glucose can improve a person's memory. Therefore, a good breakfast and a good diet can affect a person's level of concentration. Breakfast is the first food that provides energy for brain function in learning, especially concentration. The purpose of this study was to determine the relationship between breakfast, nutritional status and student concentration at STIKes PERTAMEDIKA Jakarta. Materials and Methods This study used a cross-sectional research design with 177 samples taken using the proportional stratified random sampling technique. The results of statistical analysis using chi-square showed that there was no significant relationship between breakfast and concentration of p (0.894) and no significant relationship between nutritional status and concentration of p (0.642) of students at STIKes PERTAMEDIKA Jakarta. It was found that there was no significant relationship between breakfast and concentration and there was no significant relationship between nutritional status and student learning concentration at STIKes PERTAMEDIKA.
ABSTRAKKeberhasilan proses pembelajaran dipengaruhi oleh kemampuan berkonsentrasi pada objek yang dipelajari. Konsentrasi merupakan aspek penting untuk keberhasilan belajar, Sarapan pagi bagi mahasiswa sangat penting karena mahasiswa membutuhkan energi untuk kegiatan belajar. Akibat dari mengabaikan sarapan dapat menurunkan kemampuan belajar sebab glukosa bisa meningkatkan daya ingat seseorang. Oleh karena itu, sarapan yang baik dan pola makan yang baik dapat mempengaruhi tingkat konsentrasi seseorang. Sarapan adalah makanan pertama yang menyediakan energi untuk fungsi otak dalam belajar, terutama konsentrasi. Tujuan penelitian ini untuk mengetahui hubungan sarapan, status gizi dengan konsentrasi belajar mahasiswa di STIKes PERTAMEDIKA Jakarta. Bahan dan Metode Penelitian ini menggunakan desain penelitian cross-sectional dengan 177 sampel yang diambil menggunakan teknik proportional stratified random sampling. Hasil analisis statistik menggunakan chi-square di dapatkan hasil tidak ada hubungan yang signifikan antara sarapan dengan konsentrasi p (0,894) dan tidak ada hubungan yang signifikan antara status gizi dengan konsentrasi p (0,642) mahasiswa di STIKes PERTAMEDIKA Jakarta. diperoleh bahwa tidak ada hubungan yang signifikan antara sarapan dengan konsentrasi serta tidak ada hubungan yang signifikan antara status gizi dengan konsentrasi belajar mahasiswa di STIKes PERTAMEDIKA.