bluuebunny/crossref_metadata_2025_split huggingface dataset:
p.Val142lle/p.Val122lle (C.424G>A) Transthyretin Mutation Presenting Exclusively As Small Fiber Neuropathy
Authors: Desai Urvi , Ilieva Hirstelina , Peltier Amanda 
Published: September 2022

Familial amyloid polyneuropathy is a rare autosomal dominant disorder caused by mutations in the transthyretin gene, TTR. More than 100 mutations in the TTR gene are known. p.Val30Met was identified first as a cause of FAP and is the most common mutation worldwide. p.Val30Met is associated with peripheral neuropathy while p.Val142lle (C.424G>A) (also known as p.Val122lle) is associated with cardiac amyloidosis [1, 2, 3] . In this context, we report a patient harboring p.Val142lle mutation with exclusive small fiber neuropathy and absence of any cardiac involvement representing genotypic-phenotypic heterogenicity.
Current approaches to assessing the degree of perinatal risk
Authors: Stetsenko N. A. , Fatkullina I. B. , Fayzullina L. A. , Lazareva A. Yu. , Fatkullina D. A. , Sitdikova D. G. 
Published: September 2022

Aim: to study the factors leading to adverse perinatal outcomes allowing, on this basis, to predict degree of perinatal risk.Materials and Methods. The medical records of 155 patients who performed delivery in 2019–2021 were retrospectively analyzed. The following groups were formed: main group included 56 patients with adverse perinatal outcomes (9 fetuses died antenatally, 36 fetuses born below Apgar score 5, 9 newborns died within the first 168 hours of extrauterine life, 2 infant deaths). The control group included 99 patients with favorable perinatal outcomes. While assessing the data retrieved from medical records, sociobiological and laboratory-instrumental indicators, obstetric-gynecological and somatic anamnesis, the presence of extragenital pathology, the delivery process, information related to child condition at the time of birth and in early neonatal period were analyzed.Results. In patients of the main group, significant differences were revealed compared to control group, respectively: high parity (3 or more deliveries) – 11 (19.6 %) and 15 (15.1 %) (p = 0.001); vomiting of pregnant women in early gestation – 27 (48.2 %) and 14 (14.1 %) (p = 0.005); the presence of uterine scar after two or more caesarean sections – 7 (12.5 %) and 2 (2.1 %) (p = 0.009); former abortions – 24 (42.8 %) and 16 (16.1 %) (p = 0.0017); acute respiratory viral infection in the first trimester – 21 (37.5 %) and 13 (13.1 %) (p = 0.005); threatened abortion in the second trimester – 23 (41.0 %) and 15 (15.1 %) (p = 0.0005); Doppler-based blood flow disorders in the second trimester – 17 (30.3 %) and 11 (11.1 %) (p = 0.008) and in the third trimester – 9 (16.0 %) and 3 (3.0 %) (p = 0.006); altered amniotic fluid index according to ultrasound data in the second trimester – 6 (10.7 %) and 1 (1.0 %) (p = 0.011); intrauterine growth retardation in the third trimester – 15 (26.7 %) and 4 (4.0 %) (p = 0.012); severe preeclampsia – 6 (10.7 %) and 1 (1.0 %) (p = 0.04). In patients of the main group, pregnancy was finished prematurely in 41.1 % of cases compared to 100% term delivery in control group.Conclusion. The risk factors identified, which were manifested in the first and second trimesters of pregnancy may be predictors for adverse perinatal outcomes. Based on the study results for patients of the main and control groups, it was convinced that the topic of predicting favorable and unfavorable perinatal outcome is currently far from being disclosed, which is a long meticulous path of search, analysis and comparison.
Correlation algorithm of a structurally redundant information and telecommunication network, taking into account the use of means and methods of counteraction by the enemy
Authors: Лукин К.И. , Сагдеев А.К. , Стахеев И.Г. , Титова О.В. 
Published: September 2022

Информационно-телекоммуникационная сеть относится к классу больших систем, которые не могут быть созданы за короткое время и предполагают фрагментарное развитие. По этой причине методология должна включать не только методы синтеза, алгоритмической и параметрической оптимизации, но и методы инженерного проектирования. С этой целью в статье рассматривается алгоритм построения опорного варианта структуры сети и алгоритм ее корреляции с учетом применения противником средств и методов противодействия.
The information and telecommunication network belongs to the class of large systems that cannot be created in a short time and assume fragmentary development. For this reason, the methodology should include not only synthesis methods, algorithmic and parametric optimization methods, but also engineering design methods. To this end, the article considers the algorithm for constructing a reference version of the network structure and the algorithm for its correlation, taking into account the use of counteraction means and methods by the enemy.
Experimental study of the reversible algorithm for hiding data in encrypted images based on the use of (7,4) Hamming code and MSB prediction
Authors: Бахрушина Г.И. , Жукова Т.В. , Утюпин А.Е. 
Published: September 2022

Приводятся результаты экспериментального исследования обратимого алгоритма сокрытия данных в зашифрованных изображениях, использующего код Хэмминга (7,4) и MSB-прогнозирования, который был разработан на основе алгоритма китайских исследователей Каймен Чена и Чин-Чен Чанга и реализован на языке программирования С#.
The article presents the results of an experimental study of one reversible algorithm for hiding data in encrypted images using (7,4) Hamming code and MSB prediction, which was developed based on the algorithm of Chinese researchers Kaimeng Chen and Chin-Chen Chang and implemented in the C# programming language.
Framework for creation multi-agent system
Authors: Антонов А.А. , Дук Г.В. , Чернышев С.А. 
Published: September 2022

Разработана платформа для создания имитационных моделей, в основе которых лежит мультиагентный подход. Рассмотрены существующие аналоги, а также выявлены их достоинства и недостатки. Фреймворк позволяет реализовать любую имитационную модель независимо от предметной области. Представлена архитектура ядра, стек технологий разработки. Для демонстрации работы создана имитационная модель предметной области «грузоперевозки».
The platform has been developed for creating simulation models based on a multi-agent approach. The existing analogues were considered in the work, as well as their advantages and disadvantages were identified. The framework allows you to implement any simulation model regardless of the subject area. The article presents: core architecture, development technology stack. In conclusion, a simulation model of the subject area «Cargo transportation» was created to demonstrate the work.
Algorithm for starting a multinode cluster Kubernetes and working with it in the CentOS Linux operating system
Authors: Мазманян В.Г. , Вихтенко Э.М. 
Published: September 2022

Описаны алгоритм запуска двухузлового кластера Kubernetes с использованием среды запуска контейнеров Docker в операционной системе Linux CentOS и алгоритм развертки простого веб-приложения Node.js в этом кластере.
The article describes the algorithm for running a two-node Kubernetes cluster using the Docker container runtime on Linux CentOS operating system and the algorithm for deploying a simple Node.js web application in this cluster.
A narrative review comparing clinical effectiveness of commonly used uterine balloon tamponade devices for postpartum haemorrhage management in India
Authors: Shetty Siddesh S , Moray Kusum V , Sachin Oshima , Chaurasia Himanshu , Joshi Beena 
Published: September 2022

Background: World Health Organisation recommends using Uterine Balloon Tamponade (UBT) for refractory atonic postpartum haemorrhage (PPH) management provided treatment protocols and surgical recourse is possible. Methods: This review collated literature from three electronic databases between January 2010 to December 2019 to compare clinical effectiveness, safety and use related parameters for condom-UBT, Bakri balloon and Every Second Matters (ESM) UBT devices used in India. Results: Thirty-three eligible studies reported effectiveness in managing all PPH causes ranging from 84.2% to 98.3% for condom-UBT and from 65.3% to 94.8% for Bakri-UBT. Three ESM-UBT studies reported PPH survival rates of 94% to 97.4%. Mean UBT effectiveness in controlling atonic PPH was 92.3% for condom-UBT, 84.3% for Bakri-UBT and 97.3% for ESM-UBT. Condom-UBT and Bakri-UBT were comparable across parameters whereas limited ESM-UBT evidence reported success in preventing maternal deaths. Conclusions: For limitations and heterogeneity in methodology and outcome parameters with existing evidence, a robust comparative RCT between UBT devices in India is recommended.
Being a Medical Student in the Shadow of a Pandemic: Psychological Reactions of Medical Students in the COVID-19 Pandemic and their Views on Online Learning
Authors: ÇINAR TANRIVERDİ Esra , SİNCAN Suat , ÖZKURT Zülal , ŞAHİNGÖZ Mine , KASALI Kamber , LAYIK Mehmet 
Published: September 2022

Objective: In this study, it is aimed to determine the psychological reactions of pre-clinical medical school students to the COVID-19 pandemic and their views on online learning.
Methods: A cross-sectional study was conducted on 722 medical students. Data were collected with an online questionnaire between 20 and 27 December 2020. A data collection form including questions about sociodemographic characteristics, opinions about online learning, the Impact of Event Scale-Revised, and the Insomnia Severity Index scales was used.
Results: The mean age of the participants was found to be 20.7±1.6 years. 393 (54.4%) of them were women. 671 (92.9%) of the students stated that they were concerned about the disruption of their education due to the pandemic, and 76.3% (n=551) preferred the face-to-face education environment in their schools to the online learning environment. Of the students, 181 (25.1%) had symptoms of post-traumatic stress disorder (PTSD) and 171 (23.6%) had symptoms of insomnia. The probability of posttraumatic stress disorder was higher in women than in men (OR=1.489, 95% CI=1.02-2.16; p=0.038). In those who have relatives who have contracted COVID-19, compared to those who have not (OR=1.489.95% CI=1.02-2.16; p=0.038), and those with an increased fear of COVID-19 transmission to their relatives were less likely to have PTSD symptoms than those with or without (OR=0.523, 95% CI=0.339-0.807; p=0.003). In addition, those who followed the news about COVID-19 from social media were more likely to have symptoms of PTSD in October than those who followed it from other sources (OR=0.662, 95% CI=0.461-0.951; p
Study of Genetic Variability in Production Traits of Pea (Pisum sativum) Genotypes
Authors: Kadam B. , Abhangrao A.K. , Shalaka R.S. 
Published: September 2022

Background: An experiment was carried out to measure genetic variability for yield and yield related traits in pea (Pisum sativum L.) genotypes in the Instruction cum Research Farm of Horticulture section Rajarshi chhatrapati Shahu maharaj College of Agriculture Kolhapur(Maharashtra) during winter season in the year 2018. Methods: To identify genotypes for further breeding these genotypes were evaluated in RBD design with two replications. All genotypes were grown 15 m long ridges with plant to plant distance maintained at 30 cm. To reduce experimental error, cultural practices were performed uniformly for all genotypes. Data was collected from five randomly sampled plants from each genotype and each replication. Highly significant differences were observed among the genotypes in plant height, length of pod, width of pod, number of grains per pod, shelling percentage, moisture content, tenderness, pod yield per plant.among genotypes in growth characters. Result: plant height at 15 and 30 days after sowing and upto maturity PARL-4 genotype was the best. In observation days at 50 % flowering ,colour character of the PB-29 genotypes was recorded significantly taken minimum days. In observation average number of branches overall PARL-4 genotypes was significantly highest number of branches. In weight of dry matter the genotypes IC-80-45 max.wt of dry matter.The estimates of heritability highest was found in width of pod(94.33%) number of pods per plant(93.46%), number of grains per pod (89.69%) pod yield per plants (83.51%),length of pod(80.56%) shelling percentage (77.04%) and days to 50% flowering (64.66%) heritability were moderate for tenderness (47.52%), moisture content (47.13%) and plant height at maturity (33.46%)The highest estimate of genetic advance as percent of mean was recorded for pod yield per plant (94.69%), average number of branches per plant (42.05%), number of pods per plant (41.06%), number of grains per pod (30.04%) and tenderness (25.91%). Among tested genotypes PARL-4, PB-29, IC-80-45 performed better for future generation.
CONTRIBUTION OF MOBILE BANKING INFORMATIONAL SERVICE ON CUSTOMER SATISFACTION IN TANZANIAN COMMERCIAL BANKS
Authors: Chindengwike James 
Published: September 2022

This study examined the contribution of mobile banking Informational Service on customer satisfaction. Three elements of mobile banking i.e., information service was assessed to find out the role they play on customer satisfaction at CRDB Chamwino Branch bank. The study adopted a cross sectional survey study design where data was collected at one point in time. In addition to that, both qualitative as well as quantitative approaches were employed in collecting data for triangulation. Quantitative data was collected from 99 CRDB- Chamwino Branch customers through survey, whereas, the qualitative data were collected from CRDB officials through interviews. Quantitative data was analyzed through SPSS, where, descriptive statistics as well as inferential and Logistic Regression model were used. Furthermore, the relationships between variables were established through binary Logistic Regression. The qualitative data also were analyzed through Thematic Analysis technique. Finding show there is positive significant relationship is also established between mobile banking information service and customer satisfaction with P- Value 0.002. The study concludes that mobile banking enhances customer satisfaction in commercial banks. The study recommends for more efforts to be made in making sure mobile banking technology is enhanced. Also, more investment should be made in making sure that challenges associated with mobile banking technology are minimized.
¿En qué medida el terrorismo nacionaliza?
Authors: López Romo Raúl 
Published: September 2022

El número de obras dedicadas al terrorismo vasco es ya muy amplio. En este artículo repasaremos un grupo de trabajos que aborda un problema concreto: la relación entre esa forma de violencia política y los procesos de nacionalización de masas. La mayoría de ellos son microanálisis, que es donde aún cabe aportar más investigación original, ya sea desde la historia o desde otras disciplinas. Nos detendremos en un caso concreto aún por analizar: la evolución de aquellas localidades vascas y navarras donde el tradicionalismo, con su componente católico militante y nacionalista español, obtenía en la década de 1930 unos excelentes resultados electorales. Tras el franquismo, en muchas de ellas se había pasado a votar ampliamente a una opción abertzale e izquierdista como HB, el brazo político de ETA.
Model Modernisasi Pendidikan Islam di Indonesia
Authors: Muhammad Heriyudanta  
Published: September 2022

This paper intends to research and see how the development of modern Islamic education in the modern Islamic boarding school Darussalam Gontor, Ponorogo, East Java. This type of research is library research. The data is taken from various sources of scientific literature such as books, journals, and various types of scientific works that are relevant to the research study. While the approach uses a philosophical approach. The data collection techniques used documentation techniques, then analyzed using content analysis data analysis methods. In this study, it was found that the modernization breakthrough taken by the modern Islamic boarding school Darussalam Gontor was in two forms. First, in terms of the management and management of the institution, and the second in terms of modernizing the curriculum. The management of Gontor Islamic Boarding School by waqf is intended so that the pesantren can grow more advanced, be more open, and have no shortage of future generations. While the curriculum is modernized according to the needs of human nature itself as well as according to the needs of the times. This is marked by the provision of subject matter that teaches 100% general science and 100% religious knowledge, special emphasis on aspects of mastering foreign languages, and quite complete extracurricular facilities such as skills, sports, and arts. Therefore, the modern Islamic education development model developed by the modern Darussalam Gontor Islamic boarding school is worthy of being used as a pilot project in an effort to develop Islamic education in the contemporary era.

Keywords: Model, Modernisation, Islamic Education.
Implementasi Model Pembelajaran PAUD Berbasis Sentra dan Waktu Lingkaran dalam Meningkatkan Berbagai Aspek Perkembangan Anak
Authors: Wilis Werdiningsih  
Published: September 2022

Early childhood education (PAUD) is an important stage for a child's early development. PAUD has a goal to facilitate the growth and development of children in a more measurable and comprehensive manner. A conducive environment in PAUD institutions has a positive impact on children's development. There are various kinds of learning models in early childhood, one of which is the center learning model and circle time (Beyond Centers and Circle Time/BCCT). The center learning model and the circle time or commonly referred to as the center model, is a model for implementing PAUD that focuses on children, which in the learning process is centered in the play center and uses four types of footings to support children's development. Therefore, in learning centers it is necessary to prepare for a center class and various equipment that supports learning activities in each center class. This study aims to explore in greater depth the implementation of the center-based PAUD learning model and circle time. The approach used in this study is a qualitative approach. Data obtained from interviews, observations, documentation and supported by various references related to the learning center model. The results show that the learning center model is one of the learning models that can increase student activity in learning activities, as well as improve various aspects of child development, including aspects of religious and moral values, physical-motor, cognitive, language, social-emotional, and artistic aspects.

Keywords: PAUD learning model, BCCT/central class, aspects of child development.
Multi-input Unet model based on the integrated block and the aggregation connection for MRI brain tumor segmentation
Authors: Fang Lingling , Wang Xin 
Published: September 2022

Abstract

Due to the unresectability of normal brain tissue and the extensive invasive growth of the malignant tumor, the boundary between the tumor and surrounding healthy brain tissue or blood vessels is blurred, which greatly affects the accuracy of diagnosis and treatment. Meanwhile, with the growth of data information and the development of computer equipment, it is extremely time-consuming and laborious to rely on the traditional manual segmentation of brain medical images. To solve the above problems, this paper proposes a multi-input Unet model based on the integrated block and the aggregation connection to achieve efficient and accurate segmentation of tumor structure. Besides, this paper studies two-dimensional (2D) transverse brain tumor slices to meet the needs of doctors in the actual diagnosis. It solves the low-resolution problem in sagittal and coronal planes, which can effectively improve memory efficiency. The proposed algorithm is innovative in three aspects. Firstly, by inputting the mask images which can effectively represent the tumor location characteristics, it can provide more information about the spatial relationship to alleviate the problems of fuzzy boundary and low contrast between the lesion region and healthy brain tissue. Then, the integrated block extracts the tumor local information in different receptive domains by a multi-scale convolution kernel. The aggregation connection realizes the implicit deep connection of context information, which combines the shallow and deep information of the brain with strong geometric spatial relationships. Meanwhile, to effectively alleviate the waste of memory resources caused by redundant and background information in medical images, the amount of calculation in model training is reduced by dimension reduction of the feature map. It can also overcome the gradient vanishing problem caused by network deepening. In this paper, an ablation experiment is used to verify the innovation of the proposed algorithm on the BraTS dataset, which compares with the state-of-the-art brain tumor segmentation methods. The accuracy of the proposed multi-input Unet model for the whole tumor and core lesion is 0.92 and 0.90, respectively.
Few-shot object detection model based on transfer learning and convolutional neural network
Authors: Hou Kaifa , Wang Hongmei , Li Jiayi 
Published: September 2022

Abstract
Object detection is an important research content in computer vision. Faster R-CNN has been widely used in object detection with large samples. Sample scarcity in practice makes it difficult for Faster R-CNN to extract effective feature and obtain high detection accuracy. In this paper, an improved few-shot object detection model is proposed based on Faster R-CNN. Transfer learning algorithm is applied to transfer trained weights of similar source datasets firstly. Then, attention mechanism is introduced and loss function is improved to construct the few-shot object detection model which has powerful generalization ability. Experimental results on PASCAL VOC dataset show that the proposed model can converge faster and the detection accuracy mAP reaches 79.1% which is 14.4% higher than that before the improvement. Compared with SSD and YOLO v3 network, the detection accuracy of the proposed model is also increased 31.4% and 13.1%, respectively.
Interval-Valued Fermatean Hesitant Fuzzy Sets and Infectious Diseases Application
Authors: Kirişci Murat , Simsek Necip 
Published: September 2022

Abstract
The Hesitant Fuzzy Set, a generalization of fuzzy sets, is a crucial tool for resolving the challenges associated with defining an element’s membership in a set when there is uncertainty regarding several separate values in decision-making situations. To ensure that the conditions under which experts evaluate an alternative in likely membership values and non-membership values are operational in this study, a Fermatean hesitant fuzzy set is provided. To implement multi-attributed group decision-making problems, new defined sets’ aggregate operators are defined. The primary characteristics of the new sets were investigated. Two interval-valued values are compared using a new score function and an accuracy function. Finally, a numerical example exemplifies the viability, applicability, and efficacy of the suggested approach.