bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low‐temperature thermal history of the McArthur Basin: Influence of the Cambrian Kalkarindji Large Igneous Province on hydrocarbon maturation
Authors: Nixon Angus L. , Glorie Stijn , Hasterok Derrick , Collins Alan S. , Fernie Nicholas , Fraser Geoffrey 
Published: July 2022

AbstractThe McArthur Basin of the North Australian Craton is one of the very few places on Earth where extensive hydrocarbons are preserved that were generated from Mesoproterozoic source rocks, prior to the development of extensive multicellular life. It is, however, unclear precisely when hydrocarbons from these source rocks matured, and if this occurred as a singular event or multiple phases. In this study, we present new apatite fission track data from a combination of outcrop and sub‐surface samples from the McArthur Basin to investigate the post‐depositional thermal history of the basin, and to explore the timing of hydrocarbon maturation. Apatite fission track data and thermal modelling suggest that the McArthur Basin experienced a basin‐wide reheating event contemporaneous with the eruption of the Cambrian Kalkarindji Large Igneous Province in the North and West Australian cratons, during which thick (>500 m) basaltic flows blanketed the basin surface. Reheating at ca. 510 Ma coinciding with Kalkarindji volcanism is consistent with a proposed timing of elevated hydrocarbon maturation, particularly in the Beetaloo Sub‐basin, and provides a mechanism for petroleum generation throughout the basin. Subsequent regional cooling was slow and gradual, most likely facilitated by gentle erosion (ca. 0.01–0.006 km/Ma) of overlying Georgina Basin sediments in the Devonian–Carboniferous with little structural reactivation. This model provides a framework in which hydrocarbons, sourced from Mesoproterozoic carbon‐rich rocks, may have experienced thermal maturation much later in the Cambrian. Preservation of these hydrocarbons was aided by a lack of widespread structural exhumation following this event.
A Thousand Days—A programme for vulnerable early childhood in Argentina: Targeting, dropout risk factors and correlates of time to graduation
Authors: Gonzalez Maria Sol , Santos Maria Emma 
Published: July 2022

AbstractBackgroundMil Días (A Thousand Days) is a programme for the first thousand days of life, from gestation to 2 years of age, targeted at highly vulnerable children and/or mothers and pregnant women. The programme was implemented in August 2015 in the municipality of San Miguel, in Argentina. Mil Días is designed in a holistic and intersectoral way. The main form of intervention is through home visits, but other benefits are available depending on the 51 vulnerability criteria by which participants are admitted to the programme, most of which are related to health issues. Exits of the programme occur when the mother and/or child have reversed the deprivation/s of the entrance‐criteria.MethodsThis paper provides an analysis of the programme's primary data between August 2015 and May 2019, with a total of 1,111 programme participants. First, we perform a statistical analysis of the targeted population of the programme. Second, using a logistic regression, we study factors associated to the withdrawal from the programme. Third, using survival analysis, we study the correlates of time to graduation from the programme.ResultsWe find that the programme is well‐targeted, as participants exhibit higher deprivation levels than those exhibited by beneficiaries of social programmes in general in the same municipality. We also find that programme participants in situations of most extreme vulnerability are more likely to abandon the programme and that successful exits from the programme take longer for more complex cases.ConclusionsMil Días–San Miguel is a programme for early childhood development in Argentina, which was pioneer when it was first introduced. It is well targeted and exhibits encouraging results despite complex cases taking longer to sucessfully exit the programme. In addition, the poorest poor participants are more likely to abandon the programme and so additional actions could be taken to retain them, as intended by the ‘Leave No One Behind’ 2030 commitment.
Iodine status in Danish pregnant women after an increase in iodine fortification
Authors: Knøsgaard Louise , Andersen Stig , Hansen Annebirthe Bo , Sørensen Anne , Vestergaard Peter , Andersen Stine Linding 
Published: July 2022

AbstractObjectiveIodine fortification programmes are implemented in many countries and often associated with an increase in population iodine intake. However, the initial attempt may not be sufficient and in Denmark the level of iodine added to salt was increased in 2019. Sparse evidence is available on the impact of such modification in iodine fortification. The aim of this study was to evaluate iodine status in Danish pregnant women in 2021 after this increase in iodine fortification and compare to iodine status in 2012.DesignCross‐sectional study.PatientsPregnant women in the North Denmark Region referred for routine obstetric ultrasound in 2021.MeasurementsParticipants filled out a questionnaire and delivered a spot urine. Median urinary iodine concentration (UIC) was calculated and assessed according to the recommended range in pregnancy (150–249 µg/L).ResultsAltogether 147 pregnant women were included and 88% used iodine‐containing supplements. Median UIC was overall 77 µg/L [95% confidence interval (CI): 61–96 µg/L], which was lower than in 2012 (101 µg/L [95% CI: 89–111 µg/L]) (p < 0.001). Considering sources of iodine intake in pregnancy, lower daily intake of dairy products (p = 0.008) and bread (p < 0.001) and a lower content of iodine in the supplement used (p < 0.001) was seen in 2021 compared to 2012.ConclusionDespite an increase in iodine fortification and frequent use of iodine‐containing supplements, iodine status in pregnant women in the North Denmark Region was insufficient. Results call for continued monitoring and attention to ensure adequate iodine status during pregnancy in Denmark.
Diabetes self‐management during the COVID‐19 pandemic and its associations with COVID‐19 anxiety syndrome, depression and health anxiety
Authors: Distaso Walter , Malik Mohammad M.A.H. , Semere Saba , AlHakami Amal , Alexander Emma C. , Hirani Dhruti , Shah Ronak J. , Suba Kinga , McKechnie Vicky , Nikčević Ana , Oliver Nick , Spada Marcantonio , Salem Victoria 
Published: July 2022

AbstractIntroductionThe effects of the COVID‐19 pandemic on mental health have been profound. Mental health and diabetes self‐care are inter‐related. We examined whether COVID‐19 anxiety, depressive symptoms and health anxiety were associated with domains of diabetes self‐management and investigated whether greater COVID‐19 anxiety syndrome would independently contribute to suboptimal diabetes self‐care.Research design and methodsSurveys were sent to people attending diabetes clinics of three London hospitals. Participants completed the Diabetes Self‐Management Questionnaire (DSMQ), the COVID‐19 Anxiety Syndrome Scale (C‐19 ASS), which measures perseveration and avoidant maladaptive coping behaviour, assessed with measures of co‐existent depressive symptoms and anxiety, controlling for age, gender and social deprivation. Clinical data, including pre‐ and post‐lockdown HbA1c measures, were obtained from hospital records for 369 respondents, a response rate of 12.8%.ResultsDepressive symptom scores were high. Both pre‐existing health anxiety and depressive symptoms were independently linked to improvable measures of diabetes care, as was lower socio‐economic rank. However, avoidant COVID‐19 anxiety responses were independently associated with higher diabetes self‐care scores. HbA1c levels improved modestly over the year of UK lockdown in this cohort.ConclusionDuring the height of lockdown, avoidant coping behaviours characteristic of the COVID‐19 anxiety syndrome may in fact work to improve diabetes self‐care, at least in the short term. We recommend screening for depressive symptoms and being aware of the significant minority of people with COVID‐19 anxiety syndrome who may now find it difficult to re‐engage with face‐to‐face clinic opportunities.
Banting memorial lecture 2022: ‘Type 2 diabetes and nonalcoholic fatty liver disease: Partners in crime’
Authors: Byrne Christopher D. 
Published: July 2022

AbstractNonalcoholic fatty liver disease (NAFLD) was first described in the 1980s, but in the 21st century, NAFLD has become a very common condition. The explanation for this relatively recent problem is in large part due to the recent epidemic of obesity and type 2 diabetes (T2DM) increasing the risk of NAFLD. NAFLD is a silent condition that may not become manifest until severe liver damage (fibrosis or cirrhosis) has occurred. Consequently, NAFLD and its complications often remain undiagnosed. Research evidence shows that NAFLD is extremely common and some estimates suggest that it occurs in up to 70% of people with T2DM. In the last 5 years, it has become evident that NAFLD not only increases the risk of cirrhosis, primary liver cancer and end‐stage liver disease, but NAFLD is also an important multisystem disease that has major implications beyond the liver. NAFLD increases the risk of incident T2DM, cardiovascular disease, chronic kidney disease and certain extra‐hepatic cancers, and NAFLD and T2DM form part of a vicious spiral of worsening diseases, where one condition affects the other and vice versa. Diabetes markedly increases the risk of liver fibrosis and liver fibrosis is the most important risk factor for hepatocellular carcinoma. It is now possible to diagnose liver fibrosis with non‐invasive tools and therefore it is important to have clear care pathways for the management of NAFLD in patients with T2DM. This review summarises key recent research that was discussed as part of the Banting lecture at the annual scientific conference in 2022.
Review of the genera Norellisoma Hendel and Milania Šifner (Diptera: Scathophagidae) from Japan, with description of a new species
Authors: Iwasa Mitsuhiro , Sasaki Hitoshi 
Published: July 2022

AbstractThe Japanese species of the genera Norellisoma Hendel, 1910 and Milania Šifner, 2010 of the Scathophagidae are reviewed. Of the three species of Norellisoma, N. ezoensis sp. nov. is described as new to science from Hokkaido, northern Japan. Generic redefinition of Milania and redescriptions of M. agrion (Séguy) and M. longiabdomina (Sun) are presented together with figures of diagnostic characteristics. A key to the Japanese species of Norellisoma and Milania is also provided.
Rheological properties and preclinical data of novel hyaluronic acid filler containing epidermal growth factor
Authors: Shin Sun Hye , Roh Yoon Jin , Jin Soo Chang , Hong Eun Pyo , Park Jun Kyu , Li Kapsok , Seo Seong Jun , Park Kui Young 
Published: July 2022

AbstractRecently, a novel hyaluronic acid (HA) filler containing the epidermal growth factor (EGF) was developed. The objective of this study was to evaluate the rheological properties, preclinical efficacy and biocompatibility of the EGF‐containing HA filler (HA–EGF filler) using a photoaged mouse model. The rheological properties of the new HA–EGF filler were assessed. Twenty‐four female hairless mice (SKH1) underwent photoaging induction with 8 weeks of ultraviolet‐B irradiation. The mice were randomly divided into four groups and intradermally injected 100 μl of phosphate‐buffered saline, HA–EGF filler, HA filler or polynucleotide (PN) into the dorsal region. We examined the effect of fillers on photoaged skin by dermoscopic examination. Furthermore, histological evaluation with immunohistochemical staining was performed to determine the biocompatibility and collagen formation at the 10th week. A real‐time quantitative polymerase chain reaction analysis and western blot test assessed the expression of collagen I/III, matrix metalloproteinases (MMPs) and transforming growth factor. The viscosity and elasticity of the HA–EGF filler were lower than those of the HA filler. Histological evaluation revealed no significant differences in the collagen synthesis between the HA–EGF, HA and PN filler groups. No inflammation was observed during the experimental period. The HA–EGF filler induced type I/III collagen production and downregulated the expression of MMP‐1, 3 and 9. Our results suggest that the novel HA–EGF filler may be an additional therapeutic option for photoaged skin, which works by inducing collagen synthesis. Based on these preclinical results, further well‐controlled clinical studies are required.
The past, present, and future of coral reef growth in the Florida Keys
Authors: Toth Lauren T. , Courtney Travis A. , Colella Michael A. , Kupfner Johnson Selena A. , Ruzicka Robert R. 
Published: July 2022

AbstractCoral‐reef degradation is driving global‐scale reductions in reef‐building capacity and the ecological, geological, and socioeconomic functions it supports. The persistence of those essential functions will depend on whether coral‐reef management is able to rebalance the competing processes of reef accretion and erosion. Here, we reconstructed census‐based carbonate budgets of 46 reefs throughout the Florida Keys from 1996 to 2019. We evaluated the environmental and ecological drivers of changing budget states and compared historical trends in reef‐accretion potential to millennial‐scale baselines of accretion from reef cores and future projections with coral restoration. We found that historically, most reefs had positive carbonate budgets, and many had reef‐accretion potential comparable to the ~3 mm year−1 average accretion rate during the peak of regional reef building ~7000 years ago; however, declines in reef‐building Acropora palmata and Orbicella spp. corals following a series of thermal stress events and coral disease outbreaks resulted in a shift from positive to negative budgets for most reefs in the region. By 2019, only ~15% of reefs had positive net carbonate production. Most of those reefs were in inshore, Lower Keys patch‐reef habitats with low water clarity, supporting the hypothesis that environments with naturally low irradiance may provide a refugia from thermal stress. We caution that our estimated carbonate budgets are likely overly optimistic; comparison of reef‐accretion potential to measured accretion from reef cores suggests that, by not accounting for the role of nonbiological physical and chemical erosion, census‐based carbonate budgets may underestimate total erosion by ~1 mm year−1 (−1.15 kg CaCO3 m−2 year−1). Although the present state of Florida's reefs is dire, we demonstrate that the restoration of reef‐building corals has the potential to help mitigate declines in reef accretion in some locations, which could allow some key ecosystem functions to be maintained until the threat of global climate change is addressed.
High‐performance fabricated nano‐adsorbents as emerging approach for removal of mycotoxins: a review
Authors: Song Chenggang , Qin Jianchun 
Published: July 2022

SummaryMycotoxins are highly toxic secondary metabolites produced by food‐borne fungi that can contaminate food and feed. The occurrence of mycotoxins in contaminated foodstuff can lead to serious health risks for both humans and animals, and this has attracted research interest in developing novel approaches to decontaminate mycotoxins for food safety. One of the effective ways to prevent food contamination against mycotoxins is based on efficiency adsorption. The removal of adsorbents in different food samples is a challenge that if addressed properly would enable us to overcome the contamination of multi‐mycotoxins. Recently, nano‐adsorbents and their various combinations seem to be a promising tool for capturing and removing mycotoxins from contaminated samples thanks to their excellent performance. Therefore, we have reviewed the latest literature on nano‐adsorbents based on graphene derivatives, nanoclays, inorganic hybrid nanocomposite and metal–organic frameworks for the removal of fungal toxins at both academic and industrial levels. Their synthesis, performance, security and adsorption mechanisms were summarised systematically in this study. Our work aims to provide an extensive overview of nano‐adsorbents for mycotoxin elimination, present the limitations in current research and inspire the instructive research focus on mycotoxins control in the future.
Flexible bronchoscopy indications and outcomes between indigenous and non‐indigenous patients in the Northern Territory of Australia
Authors: Seyedshahabedin Mohammad M. , Howarth Timothy P. , Mo Lin , Biancardi Edwina , Heraganahally Subash S. 
Published: July 2022

AbstractBackgroundThere is sparse evidence in the literature in relation to indications and outcomes among adult indigenous patients requiring a flexible bronchoscopy (FB). In this study, FB indications and outcomes between indigenous and non‐indigenous patients were assessed.AimTo assess the similarities and differences of FB indications and outcomes between indigenous and non‐indigenous patients.MethodsSelf‐reported indigenous status, resident locality and the primary indication for FB were assessed. The FB procedures details, results of microbiology, cytology and histopathology were compared between indigenous and non‐indigenous patients. Chest computed tomography (CT) was also analysed for its relationship to FB outcomes.ResultsOf the 403 patients, 111 (28%) were indigenous, and indigenous patients were younger (mean difference 11 years) and had a higher proportion of remote residence (70% vs 13%). Malignancy (40%) and infection (31%) were the most common indications for FB, although indigenous patients reported significantly more haemoptysis (15% vs 9%). No differences were noted in findings of the preceding chest CT scans. For positive microbiology, indigenous patients had a higher presence of Streptococcus pneumoniae (30% vs 9%), while non‐indigenous patients had a higher presence of Pseudomonas aeruginosa (43% vs 11%) and mycobacteria (15% vs 4%). There was no significant difference between indigenous and non‐indigenous patients for a positive histopathology, particularly for a diagnosis of lung malignancy (58% vs 54%).ConclusionsThis study has demonstrated that adult indigenous patients requiring a FB are significantly younger, tend to reside in remote communities and demonstrate differing microbiology with no significant difference in the diagnostic outcomes for lung malignancy. Ethnic status or remoteness should not preclude indigenous patients to undergo a FB if clinically indicated.
High fidelity dialectical behaviour therapy online: Learning from experienced practitioners
Authors: Lakeman Richard , Hurley John , Campbell Katrina , Hererra Claudia , Leggett Andrew , Tranter Richard , King Peter 
Published: July 2022

AbstractDialectical behaviour therapy (DBT) is an effective treatment for borderline personality disorder and other problems underpinned by difficulties with emotional regulation. The main components of DBT are skills training groups and individual therapy. The COVID‐19 outbreak forced a rapid adaptation to online delivery, which largely mirrored face‐to‐face programmes using videoconferencing technology. This study aimed to elicit and describe the experiences and learning of therapists involved in providing high‐fidelity DBT programmes via the Australian DBT Institute, which established an online delivery platform called DBT Assist™ prior to the COVID‐19 pandemic. The report conforms with the consolidated criteria for reporting qualitative research (COREQ). Seven therapists were interviewed. Data were transcribed and analysed thematically. Delivering skills training online, either exclusively or in hybrid form (with face‐to‐face individual therapy), was acceptable and even preferable to therapists and clients. It was considered safe, the programme was associated with few non‐completers, and it improved the accessibility of DBT to those who might otherwise not be able to engage in a face‐to‐face programme. Skills training utilized a ‘flipped‐learning’ approach which improved the efficiency of online delivery. Other unique and helpful features of the online programme were described. The best outcomes associated with online DBT are likely to be achieved through careful adaptation to the online environment in accord with the principles of DBT rather than mirroring face‐to‐face processes. Further research is required to determine the efficacy of online therapy relative to face‐to‐face, and who might be best suited to different modes of delivery.
New records of rare deep‐sea fishes (Teleostei) collected from off north‐eastern Brazil, including seamounts and islands of the Fernando de Noronha Ridge
Authors: Mincarone Michael Maia , Eduardo Leandro Nolé , Di Dario Fabio , Frédou Thierry , Bertrand Arnaud , Lucena‐Frédou Flávia 
Published: July 2022

AbstractHere we report on new data on the occurrence and distribution of rare deep‐sea fishes (Teleostei) collected from off north‐eastern Brazil, including seamounts and oceanic islands of the Fernando de Noronha Ridge (Rocas Atoll and Fernando de Noronha Archipelago). Collections were made by the French RVAnteaduring the ABRACOS (Acoustics along the BRAzilian COaSt) expeditions between 29 September and 21 October 2015, and 9 April and 10 May 2017. Occurrences ofPhotostylus pycnopterus(Alepocephalidae),Gigantura chuni(Giganturidae),Ahliesaurus berryi(Notosudidae),Benthalbella infans,Rosenblattichthys hubbsi,Scopelarchoides danae(Scopelarchidae),Scopelengys tristis(Neoscopelidae),Zu cristatus(Trachipteridae),Stylephorus chordatus(Stylephoridae) andPseudoscopelus cordilluminatus(Chiasmodontidae) are reported for the first time or confirmed in the Brazilian Exclusive Economic Zone.Photostylus pycnopterusandG. chuniare also recorded for the first time in the western South Atlantic, whereas records ofP. cordilluminatusare the first in the western Atlantic. Other records of rare species of those families are also reported and discussed.
Genome‐wide binding analysis of transcription factor Rice Indeterminate 1 reveals a complex network controlling rice floral transition
Authors: Zhang Shuo , Deng Li , Zhao Lun , Wu Changyin 
Published: July 2022

AbstractRICE INDETERMINATE 1 (RID1) plays a critical role in controlling floral transition in rice (Oryza sativa). However, the molecular basis for this effect, particularly the target genes and regulatory specificity, remains largely unclear. Here, we performed chromatin immunoprecipitation followed by sequencing (ChIP‐seq) in young leaves at the pre‐floral‐transition stage to identify the target genes of RID1, identifying 2,680 genes associated with RID1 binding sites genome‐wide. RID1 binding peaks were highly enriched for TTTGTC, the direct binding motif of the INDETERMINATE DOMAIN protein family that includes RID1. Interestingly, CACGTG and GTGGGCCC, two previously uncharacterized indirect binding motifs, were enriched through the interactions of RID1 with the novel flowering‐promoting proteins OsPIL12 and OsTCP11, respectively. Moreover, the ChIP‐seq data demonstrated that RID1 bound to numerous rice heading‐date genes, such as HEADING DATE 1 (HD1) and FLAVIN‐BINDING, KELCH REPEAT, F‐BOX 1 (OsFKF1). Notably, transcriptome sequencing (RNA‐seq) analysis revealed roles of RID1 in diverse developmental pathways. Genetic analysis combined with genome‐wide ChIP‐seq and RNA‐seq results showed that RID1 directly binds to the promoter of OsERF#136 (a repressor of rice flowering) and negatively regulates its expression. Overall, our findings provide new insights into the molecular and genetic mechanisms underlying rice floral transition and characterize OsERF#136 as a previously unrecognized direct target of RID1.