bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term outcomes of surgery using the Ligament Advanced Reinforcement System as treatment for anterior cruciate ligament tears
Authors: Smolle Maria A. , Fischerauer Stefan F. , Zötsch Silvia , Kiegerl Anna V. , Sadoghi Patrick , Gruber Gerald , Leithner Andreas , Bernhardt Gerwin A. 
Published: January 2022

Aims The aim of this prospective study was to assess the long-term clinical, radiological, functional, and quality of life (QoL)-related outcome of patients treated with the synthetic Ligament Advanced Reinforcement System (LARS) device for anterior cruciate ligament (ACL) rupture. Methods A total of 41 patients who underwent ACL reconstruction with the LARS device (mean age 39.8 years (SD 12.1 ); 32% females (n = 13)) were prospectively included between August 2001 and March 2005. MRI scans and radiographs were performed at a median follow-up of 2.0 years (interquartile range (IQR) 1.3 to 3.0; n = 40) and 12.8 years (IQR 12.1 to 13.8; n = 22). Functional and QoL-related outcome was assessed in 29 patients at a median follow-up of 12.8 years (IQR 12.0 to 14.0) and clinically reconfirmed at latest median follow-up of 16.5 years (IQR 15.5 to 17.9). International Knee Documentation Committee (IKDC) and Tegner scores were obtained pre- and postoperatively, and Lysholm score postoperatively only. At latest follow-up, range of motion, knee stability tests, 36-Item Short Form Health Survey (SF-36), and IKDC scores were ascertained. Complications and reoperations during follow-up were documented. Results Cumulative complication rate was 66% (n = 27), with 11 developing within one year from surgery and 16 after one year (including five patients with both early and late complications). Ten graft failures (24%) and eight cases of reactive synovitis were observed (20%). All 11 patients with early complications and ten with late complications underwent reoperation (including five with another surgical procedure for early complications), amounting to a cumulative reoperation rate of 51% (n = 21). Revision ACL reconstruction was performed in one patient (2.4%). Median IKDC at latest follow-up was 89.7 (IQR 78.2 to 93.1), being significantly worse in the event of previous complications. Lachman test was positive in 56% (n = 15) of reconstructed knees. All norm-based SF-36 items were at or above median at latest follow-up, and did not differ depending on development of complications. Conclusion Despite good functional and QoL-related results in the long term, the cumulative complication rate of 66%, including graft failures and reactive synovitis, has to be viewed with great concern. Cite this article: Bone Joint J 2022;104-B(2):242–248.
Wear resistance of first-generation highly cross-linked annealed polyethylene in cementless total hip arthroplasty is maintained 20 years after surgery
Authors: Orita Kazuki , Goto Koji , Kuroda Yutaka , Kawai Toshiyuki , Okuzu Yaichiro , Matsuda Shuichi 
Published: January 2022

Aims The aim of this study was to evaluate the performance of first-generation annealed highly cross-linked polyethylene (HXLPE) in cementless total hip arthroplasty (THA). Methods We retrospectively evaluated 29 patients (35 hips) who underwent THA between December 2000 and February 2002. The survival rate was estimated using the Kaplan-Meier method. Hip joint function was evaluated using the Japanese Orthopaedic Association (JOA) score. Two-dimensional polyethylene wear was estimated using Martell’s Hip Analysis Suite. We calculated the wear rates between years 1 and 5, 5 and 10, 10 and 15, and 15 and final follow-up. Results The mean follow-up period was 19.1 years (SD 0.6; 17.3 to 20.1). The 19-year overall survival rate with the end point of all-cause revision was 97.0% (95% confidence interval (CI) 91 to 100). The mean JOA score improved from 43.2 (SD 10.6; 30 to 76) before surgery to 90.2 (SD 6.4; 76 to 98) at the final follow-up (p < 0.001). There was no osteolysis or loosening of the acetabular or femoral components. The overall steady-state wear rate was 0.013 mm/year (SD 0.012). There was no hip with a steady-state wear rate of > 0.1 mm/year. There was no significant difference in wear rates for each period. We found no significant correlation between the wear rate and age, body weight, BMI, or cup inclination. Conclusion First-generation annealed HXLPE shows excellent wear resistance and no acceleration of wear for approximately 20 years, with low all-cause revision rates. Cite this article: Bone Joint J 2022;104-B(2):200–205.
Knowledge Brokerage: The Musical: an analogy for explaining the role of knowledge brokers in a university setting
Authors: Auld Megan , Doig Emmah , Bennett Sally 
Published: January 2022

Background:Knowledge brokers in higher education are described as requiring a broad range of skills and characteristics, leading to both role conflict and ambiguity. Although existing studies report broad concepts regarding the role of knowledge brokers, the activities that they actually perform to broker knowledge are not systematically reported or impact evaluated.
Aims and objectives:This paper aims to summarise the current literature on the role of knowledge brokers and describe this role in a higher education context. In an exploratory study, as two knowledge brokers we recorded our activities within a school of health in a large university setting using the Expert Recommendations for Implementation Change (ERIC) categories over a period of nine months. Using this report, we use the analogy of a musical to translate the role of knowledge broker. Considering the knowledge brokerage roles of musical director, set designer, choreographer, costume designer and sound and lighting, we discuss the impact of knowledge brokerage activities on actors relaying their knowledge story to an end-user audience. Knowledge brokers in the higher education context primarily perform activities in four areas: know your cast and crew; train your cast and crew; rehearse and review; and provide hands-on support.
Key conclusions:Understanding the role of knowledge brokers may be enhanced by using the analogy of a musical. Due to the diverse nature of these roles, it is recommended that knowledge brokerage in higher education is performed in teams, where knowledge brokers can utilise different skill sets to facilitate their work.
Multi-delay photonic correlator for wideband RF signal processing
Authors: Bourdarot Guillaume , Berger Jean-Philippe , Guillet de Chatellus Hugues 
Published: January 2022

Correlation of radio-frequency (RF) signals is a fundamental operation in many fields such as information processing, detection, and imaging techniques at large. Because of the intrinsic limitations of electronic techniques, standard digital correlators, which rely on the acquisition of signals and their processing, become very complex to implement for the real-time analysis of signals whose bandwidth exceeds a few hundred MHz. On the other hand, analog correlators are limited by the performances of RF components. In this paper, we report the proof-of-concept of a correlator architecture based on a simple photonic platform, suitable for analog wideband RF signal processing. The concept, based on multi-heterodyne interferometry, gives access in real time to the entire correlation function of two signals by computing the cross correlation coefficients for 200 values of their relative delay simultaneously. The time-delay step can be adjusted from a few ns down to a few ps, enabling us to process signals with MHz to multi-GHz bandwidth. We have applied this architecture to the localization of RF transmitters by time difference of arrival (TDoA) and obtained a precision close to 10 ps for a 100 ms integration time. This concept is expected to find practical applications in various domains, from radar and electronic warfare to telecommunications, imaging, and radio-astronomy.
Antidepressant discontinuation before or during pregnancy and risk of psychiatric emergency in Denmark: A population-based propensity score–matched cohort study
Authors: Liu Xiaoqin , Molenaar Nina , Agerbo Esben , Momen Natalie C. , Rommel Anna-Sophie , Lupattelli Angela , Bergink Veerle , Munk-Olsen Trine 
Published: January 2022

Background
Women prescribed antidepressants face the dilemma of whether or not to continue their treatment during pregnancy. Currently, limited evidence is available on the efficacy of continuing versus discontinuing antidepressant treatment during pregnancy to aid their decision. We aimed to estimate whether antidepressant discontinuation before or during pregnancy was associated with an increased risk of psychiatric emergency (ascertained by psychiatric admission or emergency room visit), a proxy measure of severe exacerbation of symptoms/mental health crisis.

Methods and findings
We carried out a propensity score–matched cohort study of women who gave birth to live-born singletons between January 1, 1997 and June 30, 2016 in Denmark and who redeemed an antidepressant prescription in the 90 days before the pregnancy, identified by Anatomical Therapeutic Chemical (ATC) code N06A. We constructed 2 matched cohorts, matching each woman who discontinued antidepressants before pregnancy (N = 2,669) or during pregnancy (N = 5,467) to one who continued antidepressants based on propensity scores. Maternal characteristics and variables related to disease severity were used to generate the propensity scores in logistic regression models. We estimated hazard ratios (HRs) of psychiatric emergency in the perinatal period (pregnancy and 6 months postpartum) using stratified Cox regression.
Psychiatric emergencies were observed in 76 women who discontinued antidepressants before pregnancy and 91 women who continued. There was no evidence of higher risk of psychiatric emergency among women who discontinued antidepressants before pregnancy (cumulative incidence: 2.9%, 95% confidence interval [CI]: 2.3% to 3.6% for discontinuation versus 3.4%, 95% CI: 2.8% to 4.2% for continuation; HR = 0.84, 95% CI: 0.61 to 1.16, p = 0.298). Overall, 202 women who discontinued antidepressants during pregnancy and 156 who continued had psychiatric emergencies (cumulative incidence: 5.0%, 95% CI: 4.2% to 5.9% versus 3.7%, 95% CI: 3.1% to 4.5%). Antidepressant discontinuation during pregnancy was associated with increased risk of psychiatric emergency (HR = 1.25, 95% CI: 1.00 to 1.55, p = 0.048). Study limitations include lack of information on indications for antidepressant treatment and reasons for discontinuing antidepressants.

Conclusions
In this study, we found that discontinuing antidepressant medication during pregnancy (but not before) is associated with an apparent increased risk of psychiatric emergency compared to continuing treatment throughout pregnancy.
Characterising co-infections with Plasmodium spp., Mansonella perstans or Loa loa in asymptomatic children, adults and elderly people living on Bioko Island using nucleic acids extracted from malaria rapid diagnostic tests
Authors: Yoboue Charlene Aya , Hosch Salome , Donfack Olivier Tresor , Guirou Etienne A. , Nlavo Bonifacio Manguire , Ayekaba Mitoha Ondo’o , Guerra Carlos , Phiri Wonder P. , Garcia Guillermo A. , Schindler Tobias , Daubenberger Claudia A. 
Published: January 2022

BackgroundRegular and comprehensive epidemiological surveys of the filarial nematodesMansonella perstansandLoa loain children, adolescents and adults living across Bioko Island, Equatorial Guinea are lacking. We aimed to demonstrate that blood retained on malaria rapid diagnostic tests, commonly deployed for malaria surveys, could be used as a source of nucleic acids for molecular based detection ofM.perstansandL.loa. We wanted to determine the positivity rate and distribution of filarial nematodes across different age groups and geographical areas as well as to understand level of co-infections with malaria in an asymptomatic population.MethodologyM.perstans,L.loaandPlasmodiumspp. parasites were monitored by qPCR in a cross-sectional study using DNA extracted from a subset malaria rapid diagnostic tests (mRDTs) collected during the annual malaria indicator survey conducted on Bioko Island in 2018.Principal findingsWe identified DNA specific for the two filarial nematodes investigated among 8.2% (263) of the 3214 RDTs screened. Positivity rates ofM.perstansandL.loawere 6.6% and 1.5%, respectively.M.perstansinfection were more prominent in male (10.5%) compared to female (3.9%) survey participants.M.perstansparasite density and positivity rate was higher among older people and the population living in rural areas. The socio-economic status of participants strongly influenced the infection rate with people belonging to the lowest socio-economic quintile more than 3 and 5 times more likely to beL.loaandM.perstansinfected, respectively. No increased risk of being co-infected withPlasmodiumspp. parasites was observed among the different age groups.Conclusions/SignificanceWe found otherwise asymptomatic individuals were infected withM.perstansandL.loa. Our study demonstrates that employing mRDTs probed with blood for malaria testing represents a promising, future tool to preserve and ship NAs at room temperature to laboratories for molecular, high-throughput diagnosis and genotyping of blood-dwelling nematode filarial infections. Using this approach, asymptomatic populations can be reached and surveyed for infectious diseases beyond malaria.
Synergistic combination of a topologically invariant imaging signature and a biomarker for the accurate prediction of symptomatic radiation pneumonitis before stereotactic ablative radiotherapy for lung cancer: A retrospective analysis
Authors: Ninomiya Kenta , Arimura Hidetaka , Yoshitake Tadamasa , Hirose Taka-aki , Shioyama Yoshiyuki 
Published: January 2022

Objectives
We aimed to explore the synergistic combination of a topologically invariant Betti number (BN)-based signature and a biomarker for the accurate prediction of symptomatic (grade ≥2) radiation-induced pneumonitis (RP+) before stereotactic ablative radiotherapy (SABR) for lung cancer.

Methods
A total of 272 SABR cases with early-stage non-small cell lung cancer were chosen for this study. The occurrence of RP+ was predicted using a support vector machine (SVM) model trained with the combined features of the BN-based signature extracted from planning computed tomography (pCT) images and a pretreatment biomarker, serum Krebs von den Lungen-6 (BN+KL-6 model). In all, 242 (20 RP+ and 222 RP–(grade 1)) and 30 cases (8 RP+ and 22 RP–) were used for training and testing the model, respectively. The BN-based features were extracted from BN maps that characterize topologically invariant heterogeneous traits of potential RP+ lung regions on pCT images by applying histogram- and texture-based feature calculations to the maps. The SVM models were built to predict RP+ patients with a BN signature that was constructed based on the least absolute shrinkage and selection operator logistic regression model. The evaluation of the prediction models was performed based on the area under the receiver operating characteristic curves (AUCs) and accuracy in the test. The performance of the BN+KL-6 model was compared to the performance based on the BN, conventional original pCT, and wavelet decomposition (WD) models.

Results
The test AUCs obtained for the BN+KL-6, BN, pCT, and WD models were 0.825, 0.807, 0.642, and 0.545, respectively. The accuracies of the BN+KL-6, BN, pCT, and WD models were found to be 0.724, 0.708, 0.591, and 0.534, respectively.

Conclusion
This study demonstrated the comprehensive performance of the BN+KL-6 model for the prediction of potential RP+ patients before SABR for lung cancer.
EDUCAÇÃO DE JOVENS E ADULTOS E INTERSECCIONALIDADE: MULHERES NEGRAS E IDOSAS, TRABALHADORAS E ESTUDANTES
Authors: Bastos Ludimila , Eiterer Carmem 
Published: January 2022

O texto apresenta análise de dados produzidos no âmbito de pesquisa de doutoramento. A pesquisa de natureza qualitativa apoia-se em entrevistas semi-estruturadas. As autoras que dão suporte as análises são principalmente Hirata (2010), Collins (2019), Bairros (1995).Discute-se a interseccionalidade como ferramenta analítica essencial para compreender as especificidades da educanda matriculada nesta modalidade de ensino. Considera-se especialmente os desafios colocados pela atuação no mundo do trabalho à partir de ocupações pouco especializadas como a de empregada doméstica. Constata-se que os atravessamentos sociais colocam estas sujeitas em situações de assimetrias de poder que se mostram obstáculos a sua frequência à escola.

Palavras-chave: Educação de jovens e adultos; interseccionalidade; gênero; raça; trabalho.
A POTÊNCIA DA REPRESENTATIVIDADE DE UMA ARIEL NEGRA: A CORPOREIDADE NEGRA COMO TERRITÓRIOS DE DESCONSTRUÇÃO DO RACISMO
Authors: Pereira Tavares Olívia 
Published: January 2022

No entrelaçamento de estudos culturais pós-estruturalistas e decoloniais, esta pesquisa partiu da repercussão da divulgação do elenco da releitura em live-action da clássica animação A pequena Sereia (1989). O anúncio que a princesa sereia dos sete mares, Ariel, ganharia vida pela interpretação da artista negra Halle Bailey causou reações no público, tanto de apoio a escolha dos estúdios Disney, quanto manifestações de racismo. Para pensar sobre esta corporeidade protagonista nas telas, foi realizado o mapeamento de jornais, revistas e blogs onlines, artigos que versassem sobre a Ariel negra. Operando com conceitos de representação e negritude, argumento que este corpo negro ressignifica a personagem sereia-princesa-protagonista, podendo ser visto como território de potência de representatividade e desconstrução do racismo.
PALAVRAS-CHAVE: Ariel negra. Corporeidade negra. Racismo. Representatividade.
Potensi Energi Arus Laut Di Perairan Selat Sunda
Authors: Nuriyati Nuriyati , Purwanto Purwanto , Setiyono Heryoso , Atmodjo Warsito , Subardjo Petrus , Ismanto Aris , Muslim Muslim 
Published: January 2022

Arus Laut merupakan salah satu sumber energi terbarukan yang potensial untuk dikembangkan mengingat banyaknya pulau dan selat yang ada di Indonesia. Selat Sunda yang berada di antara Samudera Hindia dan Laut Jawa yang dipengaruhi oleh massa air dari Samudera Pasifik menjadi salah satu lokasi potensial. Tujuan dari penelitian ini adalah untuk mengetahui karakteristik arus laut beserta potensi energi arus laut yang dihasilkan. Penelitian ini menggunakan metode kuantitatif dan penentuan lokasi dengan metode sampling area. Pengolahan data dibagi menjadi tiga tahap yaitu analisa data arus dan pasang surut, pemodelan numerik dan perhitungan estimasi rapat daya. Hasil menunjukkan bahwa kecepatan arus maksimum sebesar 1.95 m/s. Daya terbesar dihasilkan pada saat kondisi surut menuju pasang yaitu sebesar 4.51 W/m2 di daerah antara Pulau Peucang dan Ujung Kulon. Ocean current is one of the potential renewable energy sources to be developed considering there are many islands and straits that exist in Indonesia. Sunda strait that located between Indian Ocean and Java Sea be affected water masses from Pacific Ocean to be one of potential location. The purpose of this study is to determine the characteristics of ocean currents and the potential of ocean current energy that can be generated. This study used a quantitative method and determination of the location with sampling area. Data Processing is divided into 3 major phases which is analysis for currents and tides, numerical modeling and calculation of power density estimation. The results showed that the maximum of ocean current velocity is 1.95 m/s. The biggest power density is generated during ebb to flood is 4.51 W/m2in the area between Peucang island and Ujung Kulon.
Pola Arus dan Sebaran Sedimen Dasar di Perairan Jepara
Authors: Aziz Syafiq Muhammad , Rochaddi Baskoro , Handoyo Gentur , Muslim Muslim , Subardjo Petrus , Ismanto Aris 
Published: January 2022

Pantai Kartini merupakan pantai yang terletak di wilayah Kabupaten Jepara, terdapat aktifitas pelayaran yang cukup ramai. Adanya jetty dan aktivitas pengerukan di sekitar perairan Pantai Kartini dapat menyebabkan perubahan pola arus dan sebaran ukuran butir sedimen dasar. Penelitian ini bertujuan untuk mengetahui pola arus dan sebaran sedimen dasar permukaan di perairan Pantai Kartini, Jepara. Metode yang digunakan dalam penelitian ini adalah metode kuantitatif dan penentuan lokasi pengambilan sampel sedimen menggunakan metode purposive sampling. Data yang diperlukan untuk mengetahui pola arus yaitu pasang surut, dan data kedalaman perairan menggunakan instrumen singlebeam echosounder. Sedangkan data yang diperlukan untuk mengetahui persebaran ukuran butir sedimen yaitu sampel sedimen dasar. Pengolahan data menggunakan Microsoft Excel, ArcGIS 10.3, Mike21, WrPlot, worldCurrent1.0, sedangkan sampel sedimen diolah menggunkan metode pengayakan dan pemipetan. Hasil dari penelitian ini menunjukan bahwa ukuran butir sedimen dasar yang ditemukan berupa Pasir, Pasir Lanauan dan Lanau. Perairan Pantai Kartini, Jepara memiliki bilangan Formzahl (F) sebesar 1,10 sehingga tergolong pasang surut tipe campuran condong ke harian ganda. Berdasarkan hasil pengolahan software worlc current 1.0 arus rata – rata menunjukkan 74,6% arus pasut (astronomic) dan 25,5% arus non–pasut (residual). Pola arus perairan Pantai Kartini Jepara pada saat pasang menujuh ke utara dan pada saat surut menuju ke Barat Daya. Kartini Beach is a beach located in Jepara Regency, there are quite busy shipping activities. The existence of jetties and dredging activities around the waters of Kartini Beach can cause changes in flow patterns and size distribution of basic sediment grains. The purpose of this study is to determine the flow patterns and distribution of surface sediment in the waters of Kartini Beach, Jepara. The method used in this study is the quantitative method and the determination of the location of sediment sampling using the purposive sampling method. Data that needed to determine the pattern of currents namely tides, and water depth data using single beam echosounder. Meanwhile the data needed to study sediment size samples are basic sediment samples, Data processing using Microsoft Excel, ArcGIS 10.3, Mike21, WrPlot, world Current 1.0, meanwhile sediment samples are processed using filtering and pipette methods. The results of this study indicate that the size of the sediment grains found were sand, silt sand and silt. The Fromzahl (F) number is 1,10 so it is classified as a mixed tide prevailing semidiurnal. Based on the results of the processing by using World Current 1.0, as much as 74.6% of the tidal currents (astronomic) and 25.4% is non-tidal currents (residual). Flow pattern from kartini beach at high tide to the north and at low tide to the Southwest