bluuebunny/crossref_metadata_2025_split huggingface dataset:
Economics in the Social Science Spectrum: Evolution and Overlap with Different Academic Areas
Authors: Bögenhold Dieter 
Published: March 2022

AbstractCauses for the distinct and growing separation of the academic domains of economics and neighboring fields are ongoing processes of specialization, fragmentation, and evolution. Thanks to the proliferation of publications and knowledge in economics, degrees of specialization have emerged. One of the great paradoxes in economics is the existence of mainstream economics, which is taught to undergraduate students and dominates textbooks, alongside new contributions that enter the arena via other disciplines (e.g., psychology, history, and law). The paper delineates some developments in economics over the last 100 years oscillating between continuity and change. Especially, the interplay between different domains in the social sciences is discussed as fields of tension and cooperation between economics and other disciplines. The message of the article is that economics is not a homogeneous body of being, content, and learning. Economics has a diverse knowledge base on a theoretical and methodological level with different forms of economic capacity, conceptual sensitivity, and methodological rigor. Many different approaches coexist with corresponding camps of authors. A multiplicity of topics and discourses can be observed with an interesting division of economics with one branch focused on mathematics, econometric tools, and applications, and the other branch moving towards increasing social scientification with strong links to psychology, history, philosophy, and sociology. The Oxford credo of politics, philosophy, and economics (PPE) has undergone a revival in this respect.
Mandibular advancement device: prescription in adult dental sleep medicine — guideline of the German Society of Dental Sleep Medicine
Authors: Bernhardt Olaf , Giannakopoulos Nikolaos Nikitas , Heise Markus , Meyer Alexander , Norden Dagmar , Schlieper Jörg , Kares Horst 
Published: March 2022

Abstract
Purpose
Obstructive sleep apnea (OSA) may result in severe health onditions, reduces quality of live, and affects high percentages of the adult population. Due to recent changes in the German health care regulations, mandibular advancement devices (MAD) will become available as a treatment option for OSA to a greater extent for general dentists and their patients.

Methods
A guideline development group consisting of nine members representing four German dental and medical organizations was formed, in order to provide critical information and orientation to the main stakeholders (dentists and patients), regarding the use of MAD for the treatment of OSA within dental sleep medicine.

Results
This guideline aims to inform physicians and dentists, particularly those with acquired qualification/specialization in sleep medicine (or in the diagnosis and treatment of sleep-related breathing disorders), as well as experts, payers, and patients. It delivers recommendations on technical requirements for MAD prescription and fabrication, clinical procedures, maintenance, and follow-up procedures.

Conclusion
A MAD should be designed for long-term therapy and must be a custom made, adjustable, bimaxillary retained two-splint system equipped with adjustable protrusive elements. The fabrication in a dental laboratory should be based on dental impressions or scans and three-dimensional registrations of the starting position taken with a bite gauge.
Numerical study of when and who will get infected by coronavirus in passenger car
Authors: Sarhan Abd Alhamid R. , Naser Parisa , Naser Jamal 
Published: March 2022

Abstract
In light of the COVID-19 pandemic, it is becoming extremely necessary to assess respiratory disease transmission in passenger cars. This study numerically investigated the human respiration activities’ effects, such as breathing and speaking, on the transport characteristics of respiratory-induced contaminants in passenger car. The main objective of the present study is to accurately predict when and who will get infected by coronavirus while sharing a passenger car with a patient of COVID-19 or similar viruses. To achieve this goal, transient simulations were conducted in passenger car. We conducted a 3D computational fluid dynamics (CFD)-based investigation of indoor airflow and the associated aerosol transport in a passenger car. The Eulerian-Eulerian flow model coupled with k-ε turbulence approach was used to track respiratory contaminants with diameter ≥ 1 μm that were released by different passengers within the passenger car. The results showed that around 6.38 min, this is all that you need to get infected with COVID-19 when sharing a poorly ventilated car with a driver who got coronavirus. It also has been found that enhancing the ventilation system of the passenger car will reduce the risk of contracting Coronavirus. The predicted results could be useful for future engineering studies aimed at designing public transport and passenger cars to face the spread of droplets that may be contaminated with pathogens.
Hybrid-based Bayesian algorithm and hydrologic indices for flash flood vulnerability assessment in coastal regions: machine learning, risk prediction, and environmental impact
Authors: Abu El-Magd Sherif Ahmed , Maged Ali , Farhat Hassan I. 
Published: March 2022

AbstractNatural hazards and severe weather events are a matter of serious threat to humans, economic activities, and the environment. Flash floods are one of the extremely devastating natural events around the world. Consequently, the prediction and precise assessment of flash flood-prone areas are mandatory for any flood mitigation strategy. In this study, a new hybrid approach of machine learning (ML) algorithm and hydrologic indices opted to detect impacted and highly vulnerable areas. The obtained models were trained and validated using a total of 189 locations from Wadi Ghoweiba and surrounding area (case study). Various controlling factors including varied datasets such as stream transport index (STI), stream power index (SPI), lithological units, topographic wetness index (TWI), slope angle, stream density (SD), curvature, and slope aspect (SA) were utilized via hyper-parameter optimization setting to enhance the performance of the proposed model prediction. The hybrid machine learning (HML) model, developed by combining naïve Bayes (NïB) approach and hydrologic indices, was successfully implemented and utilized to investigate flash flood risk, sediment accumulation, and erosion predictions in the studied site. The synthesized new hybrid model demonstrated a model accuracy of 90.8% compared to 87.7% of NïB model, confirming the superior performance of the obtained model. Furthermore, the proposed model can be successfully employed in large-scale prediction applications.
Post-stroke enriched auditory environment induces structural connectome plasticity: secondary analysis from a randomized controlled trial
Authors: Sihvonen Aleksi J. , Soinila Seppo , Särkämö Teppo 
Published: March 2022

AbstractPost-stroke neuroplasticity and cognitive recovery can be enhanced by multimodal stimulation via environmental enrichment. In this vein, recent studies have shown that enriched sound environment (i.e., listening to music) during the subacute post-stroke stage improves cognitive outcomes compared to standard care. The beneficial effects of post-stroke music listening are further pronounced when listening to music containing singing, which enhances language recovery coupled with structural and functional connectivity changes within the language network. However, outside the language network, virtually nothing is known about the effects of enriched sound environment on the structural connectome of the recovering post-stroke brain. Here, we report secondary outcomes from a single-blind randomized controlled trial (NCT01749709) in patients with ischaemic or haemorrhagic stroke (N = 38) who were randomly assigned to listen to vocal music, instrumental music, or audiobooks during the first 3 post-stroke months. Utilizing the longitudinal diffusion-weighted MRI data of the trial, the present study aimed to determine whether the music listening interventions induce changes on structural white matter connectome compared to the control audiobook intervention. Both vocal and instrumental music groups increased quantitative anisotropy longitudinally in multiple left dorsal and ventral tracts as well as in the corpus callosum, and also in the right hemisphere compared to the audiobook group. Audiobook group did not show increased structural connectivity changes compared to both vocal and instrumental music groups. This study shows that listening to music, either vocal or instrumental promotes wide-spread structural connectivity changes in the post-stroke brain, providing a fertile ground for functional restoration.
Abschied vom Recht auf Bildung?
Authors: Butterwegge Carolin , Butterwegge Christoph 
Published: March 2022

ZusammenfassungSchulschließungen während der Covid-19-Pandemie haben nicht bloß zu Lernrückständen bei vielen Kindern und Jugendlichen geführt. Vielmehr wuchs auch die in der Bundesrepublik aufgrund der wachsenden sozialen Ungleichheit die ohnehin stark ausgeprägte Bildungsungleichheit. Hauptleidtragende der monatelangen Kita- und Schulschließungen waren Kinder aus einkommensschwachen Familien.
Psychometric evaluation of the Decision Support Tool for Functional Independence in community-dwelling older people
Authors: van Bijsterveld S. C. , Barten J. A. , Molenaar E. A. L. M. , Bleijenberg N. , de Wit N. J. , Veenhof C. 
Published: March 2022

Abstract
Background
The aging population is increasingly faced with daily life limitations, threatening their Functional Independence (FI). These limitations extend different life domains and require a broad range of community-care professionals to be addressed. The Decision Support Tool for Functional Independence (DST-FI) facilitates community-care professionals in providing uncontradictory recommendations regarding the maintenance of FI in community-dwelling older people. The current study aims to determine the validity and reliability of the DST-FI.

Methods
Sixty community-care professionals completed a twofold assessment. To assess construct validity, participants were asked to assign predefined recommendations to fifty cases of older people to maintain their level of FI. Hypotheses were tested regarding the expected recommendations per case. Content validity was assessed by questions on relevance, comprehensiveness, and comprehensibility of the current set of recommendations. Twelve participants repeated the assessment after two weeks to enable both within- and between rater reliability properties, expressed by an Intraclass Correlation Coefficient.

Results
Seven out of eight predefined hypotheses confirmed expectations, indicating high construct validity. As the recommendations were indicated ‘relevant’ and ‘complete’, content validity was high as well. Agreement between raters was poor to moderate while agreement within raters was moderate to excellent, resulting in moderate overall reliability.

CONCLUSION
The DST-FI suggests high validity and moderate reliability properties when used in a population of community-dwelling older people. The tool could facilitate community-care professionals in their task to preserve FI in older people. Future research should focus on psychometric properties like feasibility, acceptability, and developing and piloting strategies for implementation in community-care.
Deep learning for evaluation of microvascular invasion in hepatocellular carcinoma from tumor areas of histology images
Authors: Chen Qiaofeng , Xiao Han , Gu Yunquan , Weng Zongpeng , Wei Lihong , Li Bin , Liao Bing , Li Jiali , Lin Jie , Hei Mengying , Peng Sui , Wang Wei , Kuang Ming , Chen Shuling 
Published: March 2022

Abstract
Background
Microvascular invasion (MVI) is essential for the management of hepatocellular carcinoma (HCC). However, MVI is hard to evaluate in patients without sufficient peri-tumoral tissue samples, which account for over a half of HCC patients.

Methods
We established an MVI deep-learning (MVI-DL) model with a weakly supervised multiple-instance learning framework, to evaluate MVI status using only tumor tissues from the histological whole slide images (WSIs). A total of 350 HCC patients (2917 WSIs) from the First Affiliated Hospital of Sun Yat-sen University (FAHSYSU cohort) were divided into a training and test set. One hundred and twenty patients (504 WSIs) from Dongguan People’s Hospital and Shunde Hospital of Southern Medical University (DG-SD cohort) formed an external test set. Unsupervised clustering and class activation mapping were applied to visualize the key histological features.

Results
In the FAHSYSU and DG-SD test set, the MVI-DL model achieved an AUC of 0.904 (95% CI 0.888–0.920) and 0.871 (95% CI 0.837–0.905), respectively. Visualization results showed that macrotrabecular architecture with rich blood sinus, rich tumor stroma and high intratumor heterogeneity were identified as the key features associated with MVI ( +), whereas severe immune infiltration and highly differentiated tumor cells were associated with MVI (−). In the simulation of patients with only one WSI or biopsies only, the AUC of the MVI-DL model reached 0.875 (95% CI 0.855–0.895) and 0.879 (95% CI 0.853–0.906), respectively.

Conclusion
The effective, interpretable MVI-DL model has potential as an important tool with practical clinical applicability in evaluating MVI status from the tumor areas on the histological slides.

Graphical abstract
Radiomics analysis of contrast-enhanced CT for staging liver fibrosis: an update for image biomarker
Authors: Wang Jincheng , Tang Shengnan , Mao Yingfan , Wu Jin , Xu Shanshan , Yue Qi , Chen Jun , He Jian , Yin Yin 
Published: March 2022

Abstract
Background
To establish and validate a radiomics-based model for staging liver fibrosis at contrast-enhanced CT images.

Materials and methods
This retrospective study developed two radiomics-based models (R-score: radiomics signature; R-fibrosis: integrate radiomic and serum variables) in a training cohort of 332 patients (median age, 59 years; interquartile range, 51–67 years; 256 men) with biopsy-proven liver fibrosis who underwent contrast-enhanced CT between January 2017 and December 2020. Radiomic features were extracted from non-contrast, arterial and portal phase CT images and selected using the least absolute shrinkage and selection operator (LASSO) logistic regression to differentiate stage F3–F4 from stage F0–F2. Optimal cutoffs to diagnose significant fibrosis (stage F2–F4), advanced fibrosis (stage F3–F4) and cirrhosis (stage F4) were determined by receiver operating characteristic curve analysis. Diagnostic performance was evaluated by area under the curve, Obuchowski index, calibrations and decision curve analysis. An internal validation was conducted in 111 randomly assigned patients (median age, 58 years; interquartile range, 49–66 years; 89 men).

Results
In the validation cohort, R-score and R-fibrosis (Obuchowski index, 0.843 and 0.846, respectively) significantly outperformed aspartate transaminase-to-platelet ratio (APRI) (Obuchowski index, 0.651; p < .001) and fibrosis-4 index (FIB-4) (Obuchowski index, 0.676; p < .001) for staging liver fibrosis. Using the cutoffs, R-fibrosis and R-score had a sensitivity range of 70–87%, specificity range of 71–97%, and accuracy range of 82–86% in diagnosing significant fibrosis, advanced fibrosis and cirrhosis.

Conclusion
Radiomic analysis of contrast-enhanced CT images can reach great diagnostic performance of liver fibrosis.
Fabrication of Ce-ReS2 by Molten Salt for Electrochemical Hydrogen Evolution
Authors: Chen Ran , Ma Minghai , Luo Yi , Qian Liping , Wan Shunli , Xu Shengyou , She Xinsong 
Published: March 2022

AbstractRenewable and economical generation of hydrogen via electrochemical methods shows great potential in addressing the energy crisis. In this study, an emerging molten salt method was adopted for the synthesis of a cerium-modified rhenium disulfide nanosheet for electrical hydrogen evolution reactions. The prepared 1% Ce-doped rhenium disulfide (ReS2) sample showed promoted hydrogen evolution performance in both acid and alkaline electrolytes compared to bare ReS2. Generating of abundant defects in ReS2 exposed more reaction active sites. Moreover, adding cerium accelerated the hydrogen evolution dynamics. Hopefully, this work will offer new insight into developing ReS2-based electrocatalysts for hydrogen evolution reactions.
Transcatheter edge-to-edge repair of tricuspid regurgitation in the Netherlands: state of the art and future perspectives
Authors: Krikken Jan A. , van den Heuvel Ad F. M. , Willemsen H. Marco , Voors Adriaan A. , Lipsic Erik 
Published: March 2022

AbstractDespite the high prevalence and adverse clinical outcomes of severe tricuspid regurgitation (TR), conventional treatment options, surgical or pharmacological, are limited. Surgery is associated with a high peri-operative risk and medical treatment has not clearly resulted in clinical improvements. Therefore, there is a high unmet need to reduce morbidity and mortality in patients with severe TR. During recent years, several transcatheter solutions have been studied. This review focuses on the transcatheter edge-to-edge repair of TR (TTVR) with respect to patient selection, the procedure, pre- and peri-procedural echocardiographic assessments and clinical outcomes. Furthermore, we highlight the current status of TTVR in the Netherlands and provide data from our initial experience at the University Medical Centre Groningen.
Lithofacies characterization and source rock assessment of the lower-middle Miocene Successions in the northern part of Ramadan oil field, central Gulf of Suez, Egypt
Authors: El Nady Mohamed M , Ramadan Fatma S. , El Hemimey Wafaa A. , Saleh Ahmed H. 
Published: March 2022

Abstract
Facies of rifting basins reflect different depositional environments from deep to shallow conditions. The present study focuses on subsurface facies characterization and source rock assessment of Kareem and Rudeis rocks in six wells lying in the central Gulf of Suez. The distribution of the lithologic patterns delineated through several constructed facies maps. Porosity cross-plots of Kareem and Rudeis formations to determine the rock minerals and porosity attitudes. Rock–Eval pyrolysis was applied to determine the kerogen type, organic matter richness, percentage, and maturation of the source rocks. The greater depth of the two formations was reflected in the western parts while their stratigraphic thickness increases toward the east and the north directions, with decreasing thickness towards the west direction due to an underlain basin structure of the pre-Miocene. Isolith maps show three deep marine lithologies for the two formations with the anhydrite as a fourth shallow marine lithology in the Kareem Formation only. These lithofacies reflect the turnover from the deep to the shallow depositional environment. The facies change from a main shaly limestone in the Rudeis Formation to calcareous shale in the Kareem formation, indicating transmutation from the lower Miocene deep to the middle Miocene shallow marine environments. The cross-plots reflected the existence of limestone, shale, and anhydrite. Geochemically, both formations are marginally good source rock with a marginally good generation of mixed type II/III and type III. Accordingly, Rudeis and Kareem formations could be good reservoirs rather than being potential source rocks in the central Gulf of Suez.
New insights in the investigation of trepanations from the Carpathian Basin
Authors: Király Kitty , Váradi Orsolya Anna , Kis Luca , Nagy Réka , Elekes Gréta , Bukva Mátyás , Tihanyi Balázs , Spekker Olga , Marcsik Antónia , Molnár Erika , Pálfi György , Bereczki Zsolt 
Published: March 2022

AbstractThe aim of this study is to describe four new cases of trepanation from the Great Hungarian Plain and complement two other previously published cases with new results from the 9th to 16th c. CE. Sex determination and age-at-death estimation were performed using classical macromorphological methods. In certain cases, radiographic imaging, 3D scanning, and radiocarbon dating were also performed. Our cases fit the formerly established understanding of trepanations, with a male majority and signs of trauma as accompanying symptoms. The cause of intervention was mostly therapeutic, i.e., trauma, in most cases. In order to simplify the currently confusing nomenclature in trepanation categories (complete–incomplete vs. surgical–symbolic), we propose the use of “trepanation” exclusively to all forms of intentional, non-violent removals of all three layers of the cranial vault. On the other hand, the phenomena widely known in Eastern Europe as symbolic trepanations should be designated as “cranioglyphs,” referring to all forms of superficial interventions administered to the cranial vault that do not penetrate all three layers of the bone. In case the data are insufficient to properly categorize the phenomenon at hand, one should refrain from it, and simply describe the lesion as intentional cranial intervention. In order to bring spotlight to the wide range of cranial interventions in the early medieval Carpathian Basin, our team is conducting several research projects, in order to contribute to a better understanding of these traditions in the future.
Intervention Fidelity of Telephone Motivational Interviewing On Physical Activity, Fruit Intake, and Vegetable Consumption in Dutch Outpatients With and Without Hypertension
Authors: Mesters Ilse , van Keulen Hilde M. , de Vries Hein , Brug Johannes 
Published: March 2022

Abstract
Background
In theory, Motivational Interviewing (MI) fidelity should be associated with client outcomes. Nevertheless, this fidelity-effectiveness association is rarely investigated. This study evaluated the extent to which Telephone Motivational Interviewing (TMI) fidelity is associated with change in self-reported physical activity (PA), fruit intake, and vegetable consumption.

Method
Adults in primary care (45–70 years) participated in a study that compared the effect of tailor print communication, telephone motivational interviewing (TMI), and a combination of the two on PA, fruit intake, and vegetable consumption. MI fidelity was assessed using the behavioral coding method “Motivational Interviewing Treatment Integrity Code (MITI)” in 409 randomly selected audio-recorded sessions, representing 232 participants of the TMI group. The associations between MI fidelity scores and the behavioral changes from baseline to 47-week follow-up were examined using backward multiple linear regression analyses (adjusted for covariates).

Results
A significant and positive association between the percentage of MI adherent responses and improvements in PA and fruit consumption was found with respectively a small and medium effect size. The global rating “Spirit” (which resembles an all-at-once appraisal of the interviewer’s MI competence) was significantly, but inversely associated with progress in vegetable intake with a medium effect size.

Conclusion
The finding that relatively lower MI competency was associated with higher vegetable consumption went against our expectations. Findings suggest that practicing MI-consistent skills was beneficial in promoting PA and fruit consumption, but moderated vegetable intake. This study contributes to the scientific confidence that TMI enables change in PA and fruit intake.