bluuebunny/crossref_metadata_2025_split huggingface dataset:
Financial inclusion and their role in renewable energy and non-renewable energy consumption in China: Exploring the transmission channels
Authors: Li Yukun , Chen Jian , Sohail Muhammad Tayyab 
Published: March 2022

Abstract
China is the most polluted economy in the world, facing the challenges of increased CO2 emissions. In this way, energy consumption is a key factor in CO2 emissions. To this end, this study empirically examines the effects of financial inclusion and education on energy consumption employing the ARDL approach for China during the period 1995–2019. The results suggest that financial inclusion has a positive effect on renewable energy consumption, but a negative impact on renewable energy and total energy consumption. The results show that education reduces non-renewable consumption and increases renewable energy consumption in the long-term. Long-run and short-run findings are also consistent and robust in the sensitivity analysis. Based on findings, China should invest in the education sector and increase financial inclusion to reduce energy consumption to meet environmental sustainability.
First observation of the proton emitter 116La: Evidence for strong neutron-proton pairing from proton separation energies and emission probabilities
Authors: Zhang Wei , Cederwall Bo , AKTAS Ozge , Liu Xiaoyu , Ertoprak Aysegül , Nyberg Ayse , Auranen Kalle , Alayed Betool , Badran Hussam , Boston Helen , Doncel Maria , Forsberg Ulrika , Grahn Tuomas , Greenlees Paul , GUO Song , Heery Jacob , Hilton Joshua , Jenkins David , Julin Rauno , Juutinen Sakari , Luoma Minna , Neuvonen Olavi , Ojala Joonas , Page Robert , Pakarinen Janne , Paul Edward , Petrache Costel , Rahkila Panu , Ruotsalainen Panu , Sandzelius Mikael , Sarén Jan , Szwec Stuart , Tann Holly , Uusitalo Juha , Wadsworth Robert 
Published: March 2022

Abstract
The discovery of the new proton emitter $^{116}_{~57}$La$_{59}$, 23 neutrons away from the only stable La isotope, $^{139}_{~57}$La$_{82}$, is reported. The $^{116}$La nuclei were synthesised in the fusion-evaporation reaction $^{58}$Ni($^{64}$Zn, p4n)$^{116}$La and identified via their proton radioactivity using the MARA mass spectrometer and the silicon detectors placed at its focal plane. Comparisons of the measured proton energy ($E_{p} = 718 \pm 9 $ keV) and half-life ($T_{1/2} = 50 \pm 22$ ms) with values calculated using %microscopic nuclear barrier penetration theory
the Universal Decay Law approach indicate that the proton is emitted with an orbital angular momentum $l=2$ and that its emission probability is enhanced relative to its closest, less exotic, odd-even lanthanum isotope ($^{117}_{~57}$La$_{60}$) while the proton-emission $Q$-value is lower. We propose this to be a signature for the presence of strong neutron-proton pair correlations in this exotic, neutron deficient system. The observations of $\gamma$ decays from isomeric states in $^{116}$La and $^{117}$La are also reported.
Accountability in healthcare in the Netherlands: A scoping review
Authors: Kerkvoorden Dennis Van , Ettema Roelof , Minkman Mirella 
Published: March 2022

Abstract
Accountability in health services is necessary for legitimacy, transparency, financial and managerial justification. To achieve the best possible outcomes for people at an affordable cost, healthcare services are continuously evolving. One development is the movement to person-centred integrated care to better serve people’s individual needs. This requires inter-organisational cooperation and service provision by domain-overarching networks and alliances. Accountability traditionally focuses on professionals and organisations. In the development towards inter-organisational networks, it is relevant to explore which accountability approaches are appropriate for local inter-organisational healthcare governance. Therefore, in this study we provide insight into the state of play of accountability in Dutch healthcare.MethodsFor systematically mapping and addressing the exploratory nature of the topic of accountability in healthcare in the Netherlands, we executed a scoping review. Databases were searched from January 2009 to March 2021. The following aspects of accountability are mapped: keywords of accountability, domains, stakeholders and target audiences, the aim (why), content (what) and method (how) of accountability, who is accountable to whom, and reported issues in accountability in Dutch healthcare practice. ResultsForty-one studies were included, of which twenty were in the hospital domain. Definitions of accountability were mostly absent. Involved stakeholders include mainly medical and managerial professionals in practice and supervisory boards. Most frequently reported issues were the relationship between performance management and accountability, different views of stakeholders about both accountability and perverse effects. Accountability covering integrated care was rarely described.ConclusionsAccountability is not only a method for legitimacy or transparency. It relates to how to judge performance, on what basis and towards whom. Current, accountability practice does not focus on or comply with the characteristics of integrated service delivery and is merely single profession or single organisation focussed. Issues like perverse effects, absence of trust, and preventing bureaucracy are relevant for further development of effective accountability. New guiding principles for accountability that suit integrated health-service delivery in the Netherlands should be developed.
Aldehyde Dehydrogenase 2 Activator Augments the Beneficial Effects of Empagliflozin in Diabetes Aassociated HFpEF
Authors: Pan Guodong , Roy Bipradas , Giri Shailendra , Lanfear David E , Thandavarayan Rajarajan A. , Guha Ashrith , Ortiz Pablo , Palaniyandi Suresh Selvaraj 
Published: March 2022

Abstract
Objectives: To ameliorate diabetes mellitus associated heart failure with preserved ejection fraction (HFpEF), we plan to lower diabetes-mediated oxidative stress-induced 4-hydroxy-2-nonenal (4HNE) accumulation by pharmacological agents that either decrease 4HNE generation or increase its detoxification.Background: 4HNE, a cellular reactive carbonyl species (RCS), was significantly increased in diabetic hearts due to a diabetes-induced decrease in 4HNE detoxification by aldehyde dehydrogenase (ALDH)2, a cardiac mitochondrial enzyme that metabolizes 4HNE. Therefore, hyperglycemia-induced 4HNE is critical for diabetes-mediated cardiotoxicity and we hypothesize that lowering 4HNE ameliorates diabetes associated HFpEF. Methods: We fed high-fat diet to ALDH2*2 mice which have intrinsically low ALDH2 activity to induce type-2 diabetes. After 4 months of diabetes, the mice exhibited features of HFpEF and along with increased 4HNE adducts and we treated them with vehicle, empagliflozin (EMP) (3mg/kg/d) to reduce 4HNE and Alda-1 (10mg/kg/d), an ALDH2 activator to enhance ALDH2 activity as well as a combination of EMP + Alda-1 (E + A), via subcutaneous osmotic pumps. After 2 months of treatments, cardiac function was assessed by conscious echocardiography before and after exercise stress. Results: EMP + Alda-1 improved exercise tolerance, diastolic and systolic function, 4HNE detoxification and cardiac liver kinase B1 (LKB1)-AMP-activated protein kinase (AMPK) pathway in ALDH2*2 mice with diabetes associated HFpEF. This combination was even more effective than EMP alone. Conclusions: Our data indicate that ALDH2 activation along with the treatment of hypoglycemic agents may be a salient strategy to alleviate diabetes associated HFpEF.
Effects of Parenting Mode on Student Adaptability: The Mediating Effect of Irrational Beliefs
Authors: Kong Hua , Hongwang Xu , Yujian Deng , Xuefeng Wang , Wei Zhang 
Published: March 2022

Abstract
Backgrounds: When facing the new growth field of university, some college students will quickly form good university adaptation, while others will have maladaptation behavior. The students’ adaptations of to the growth environment in universities and smooth transition to adulthood are the important topics in recent years. Methods：Present study introduces irrational beliefs to investigate the effects of parenting mode on maladaptation of university students. The questionnaires based on simplified parenting mode (Chinese), irrational belief and adaptability were administered in a survey of 510 university students in Zhanjiang on October, 2021, by using the random sampling method. Parenting mode was used as the independent variable, while the emotionally warm, overprotective and rejecting types were used as the indices. Further, the irrational beliefs including summary comments, awful beliefs and low tolerance to setbacks as well as maladaptation were included in the mediation model for analysis.Results: The results showed that emotionally warm parenting mode was negatively correlated with summary comments (r = -0.334), awful beliefs (r = -0.108) and low tolerance to setbacks (r = -0.153). The rejection parenting mode was negatively related with absolute requirements (r = -0.143), and learning motivation (r = -0.157), interpersonal adaptation (r = -0.283) and physical and psychological adjustment(r=-0.083). Overprotection was negatively correlated with absolute requirements (r = -0.042) and interpersonal adaptation (r = -0.042). The mediating effect of irrational beliefs (low tolerance to setbacks, awful beliefs and absolute requirements), the lower and upper limits of Bootstrap confidence interval were 0.141 and 0.532, respectively, excluding 0, which indicated that the mediating effect is true. Conclusion: Through the analysis of the data, this study believes that irrational beliefs such as low tolerance to setbacks, awful beliefs and absolute requirements mediate the effects on school adjustment. Parenting mode can influence adaptability of university students. Emotionally warm parents strengthen the adaptability of university students. By contrast, negative parenting modes such as overprotection and rejection inculcate irrational beliefs, resulting in maladaptation of university students.
Application of Machine Learning for Inter Turn Fault Detection in Pumping System
Authors: Dutta Nabanita , Kaliannan Palanisamy , Shanmugam Paramasivam 
Published: March 2022

Abstract
Pump fault diagnosis is essential for maintenance and safety of the device as it is an important appliance used in various major sectors. Fault diagnosis at proper time can reduce maintenance cost and save energy. In this article a Simulink model based on mathematical equations has been built for analyzing the effects of parameter estimation of three phase induction motor based centrifugal pump in inter turn fault condition. The inter turn fault causes huge increase of current which severely affects the parameters of both motor and pump and these have been analysed by simulation through Matlab Simulink model. Later, the results are verified by hardware in loop (HIL) based simulator. In this paper machine learning (ML) based artificial neural network (ANN) and ANFIS (ANN and Fuzzy) models have been applied for fault detection ANN and ANFIS based models provide a satisfactory level of accuracy. These models provide accurate training and testing results. Based on root mean square error (RMSE), R2, prediction accuracy and mean validation value these models are compared to find out which is more suitable for this experiment. Various supervised algorithms are compared with ANN, ANFIS and lastly found which is the most suitable for this experiment.
Cell surface accumulation of intracellular leucine proline-enriched proteoglycan 1 enhances odontogenic potential of human dental pulp stem cells
Authors: Kang Kyung-Jung , Min Tae-Jun , Choi Min-Jeong , You Tae Min , Lee Gyutae , Ko Seon-Yle , Jang Young-Joo 
Published: March 2022

Abstract
Primary dental pulp cells can be differentiated into odontoblasts, which are responsible for dentin formation and mineralization. Successful differentiation has been verified using a few markers. However, odontoblast-specific cell surface markers have not been fully studied yet. Previously, we have constructed monoclonal antibodies to identify cell surface molecules of odontoblasts by decoy immunization. Mass spectrometry confirmed that one of these antibodies, the anti-OD40 antibody, recognized LEucine PRoline-Enriched Proteoglycan 1 (LEPRE1) as a specific antigen. Among three alternative splicing isoforms of LEPRE1, this new antibody showed the most stable antigenic affinity for LEPRE1a, a canonical transcript. Anti-OD40 antibody could strongly bind to the cell surface as odontogenic differentiation progressed. Intracellular and cell surface accumulation of this protein completely disappeared during dentin maturation and mineralization. Overexpression and knock-down experiments showed that intracellular LEPRE1/OD40 should not accumulate too much and that it should move from ER to the cell surface for efficient odontogenic differentiation. Indeed, when LEPRE1/OD40 already located on the cell surface was blocked with antibody, odontogenic differentiation of human dental pulp cells was inhibited. In addition to its role in differentiation, our new antibody which only recognizes LEPRE1a isoform specifically will be useful in studying differentiated functions between LEPRE1a and other isoforms found in osteogenesis imperfecta and dentinogenesis imperfecta.
Perceptions and attitudes about antibiotic resistance in the general public and general practitioners in France
Authors: MENARD Colette , FEGUEUX Sophie , HERITAGE Zoë , NION-HUANG Michèle , BERGER-CARBONNE Anne , BONMARIN Isabelle 
Published: March 2022

Abstract
Background
During the last 20 years, France has taken important steps to tackle antibiotic resistance. These include national awareness campaigns for the general public, and supporting changes in terms of antibiotic prescription for healthcare practitioners. We conducted two surveys prior to the commencement of the upcoming 2022/2023 campaign, to explore the general public’s knowledge, attitudes and behaviours regarding antibiotics and also the perceptions and practices of general practitioners (GPs).
Methods
In 2019, we conducted a telephone survey in a national representative quota sample of 1204 persons aged over 15 years old living in metropolitan France, including an over-sample of 332 parents of children six years old or younger. In 2020, an online survey was conducted in a national representative sample of 388 GPs. Comparisons were made with similar telephone and online surveys conducted in 2010.
Results
Twenty-seven percent of respondents reported taking antibiotics during the previous year (31% in 2010). Sixty-five percent of GPs declared prescribing fewer antibiotics during the previous five years. However, 92% of GPs reported pressure from their patients for an antibiotic prescription (88% in 2010). The pressure from elderly patients increased notably between the two study periods. Twenty-three percent of respondents reported putting pressure on their GP (15% in 2010). All respondents expressed total trust in their GP irrespective of whether s/he had prescribed them antibiotics. Half knew that antibiotics act only on bacteria, and 38% understood precisely what antibiotic resistance is.
Conclusion
Although antibiotic use is decreasing in France, patient pressure on GPs to prescribe antibiotics has increased. GPs are key ambassadors in reducing antibiotic use. Awareness campaigns must target elderly patients in particular.
Pentatrichomonas hominis and other intestinal parasites in school-aged children: Clinical and coproscopic survey
Authors: Abdo Sarah Mohamed , Ghallab Marwa , Elhawary Nagwa , Elhadad Heba 
Published: March 2022

Abstract
Pentatrichomonas hominis (P.hominis) is a large intestinal flagellated protozoan infecting humans. Little is known about the epidemiology of P.hominis in Egypt, its association with gastrointestinal symptoms and the co-infection with other parasites. Demographic and clinical data were collected from 180 school-aged children. Parasitological examination of fecal samples was done using direct wet mount, formalin ethyl-acetate, Kato-Katz and cultivation on Jones' medium to detect P.hominis and associated parasitic infection. The diagnosis of P.hominis was confirmed using Giemsa stain and scanning electron microscopy. The prevalence of P. hominis was 13.8% (25 out of 180 children). The prevalence of parasitic co-infection was significantly higher in P.hominis infected (84%, 21 participants) than in non-infected children (56%, 87 participants).The presence of abdominal pain and diarrhea in P.hominis infected children was higher than in non-infected children (84% and 32% vs. 76% and 18%), respectively. The difference was not statistically significant. This is the first report of P.hominis in Egypt. The significant association between P.hominis and other intestinal parasites may highlight the pathogenicity of P.hominis. Further studies are needed to understand the epidemiology and pathogenicity of P.hominis.
A Green Approach to the Removal of Malachite Green Dye from Aqueous Medium Using Chitosan/Cellulose blend
Authors: Shetty Bhavyashri , R Yashodha S , Johns Jobish 
Published: March 2022

Abstract
The usage of cost effective, ecofriendly and highly efficient adsorbent to the removal of dye from aqueous solution is presented in this paper. This work focusses on the prospective use of Chitosan/Cellulose blend to remove the Malachite green (MG) from aqueous medium. Optimization of experimental conditions to find the maximum dye adsorption is studied in detail. Results revealed that the maximum adsorption of dye occurs within 30 minutes of the experiment. The SEM images exhibited a change in its surface morphology upon the adsorption of dye. The adsorption isotherm of MG clearly fits the Langmuir and Freundlich equations and follows pseudo-second-order rate equation. Freundlich isotherm exhibited the maximum adsorption capacity of 115.1 mg/g when compared to Langmuir isotherm. 98.65% of dye degradation is observed at room temperature for an adsorbent dosage of 0.2g per 30 ml initial dye concentration. Current analysis and its comparison studies with other reports on adsorbents concludes that, Chitosan/Cellulose blend can be considered as a cost effective choice for the removal of MG.
Study On The Causes Of Coal Mine Production Safety Risks
Authors: Zhang Ru , Jia Baoshan , Shen Zhuo , Su Guorui 
Published: March 2022

Abstract
This study analyzed the influence of risk factors of coal mine safety based on WSR (Wili-Shili-Renli) theory. We established a coal mine safety risk index system of the “human-machine-ring-tube” by applying the decision-making experimental analysis method to calculate the centrality of coal mine safety risk factors. Interpretative structural modeling was applied to determine the relationships among the coal mine safety risk factors. The improved CRITIC empowerment method was then applied to establish a coal mine safety risk cause model, and the degree of comprehensive impact was determined. The results showed that the main risk factors affecting coal mine safety were: three violations rates of personnel, safety inspection rate, safety management system, hidden danger rectification, equipment reliability rate, safety monitoring system operation status, comprehensive quality of personnel, personnel operation and safety awareness, and video monitoring system operation status.
Origin of thyrotropin-releasing hormone neurons that innervate the tuberomamillary nuclei
Authors: Sánchez-Jaramillo Edith , Wittmann Gábor , Menyhért Judit , Singru Praful , González Gabriela Berenice Gómez , Islas Eduardo Sánchez , Recendis Nashiely Yáñez , Cabrera Jaime Arturo Pimentel , Olea Martha León , Gereben Balazs , Fekete Csaba , Charli Jean Louis , Lechan Ronald Michael 
Published: March 2022

Abstract
Hypophysiotropic TRH neurons function as metabolic sensors that regulate the thyroid axis and energy homeostasis. Less is known about the role of other hypothalamic TRH neurons. As central administration of TRH decreases food intake and increases histamine in the tuberomammillary nuclei (TMN), and TMN histamine neurons are densely innervated by TRH fibers from an unknown origin, we mapped the location of TRH neurons that project to the TMN. The retrograde tracer, cholera toxin B subunit (CTB), was injected into the TMN E1-E2, E4-E5 subdivisions of adult Sprague Dawley male rats. TMN projecting neurons were observed in the septum, preoptic area, BNST, perifornical area, anterior PVN, peduncular and tuberal lateral hypothalamus (TuLH), suprachiasmatic nucleus and medial amygdala. However, CTB/pro-TRH178-199 double-labeled cells were only found in the TuLH. The specificity of the retrograde tract-tracing result was confirmed by administering the anterograde tracer, Phaseolus vulgaris leucoagglutinin (PHAL) into the TuLH. Double labeled PHAL-pro-TRH boutons were identified in all subdivisions of the TMN. TMN neurons double labeled for histidine decarboxylase ( Hdc )/PHAL, Hdc / Trhr , and Hdc / Trh . Further confirmation of a TuLH TRH neuronal projection to the TMN was established in a transgenic mouse that expresses Cre-recombinase in TRH-producing cells following microinjection of a Cre-recombinase–dependent AAV that expresses mCherry into the TuLH. We conclude that in rodents, the TRH innervation of TMN originates in part from TRH neurons in the TuLH and that this TRH population may contribute to regulate energy homeostasis through histamine Trhr- positive neurons of the TMN.
Plastic Impurities In Biowaste Treatment: Environmental And Economic Life Cycle Assessment Of A Composting Plant
Authors: Bottausci Sara , Magrini Chiara , Tuci Giulia Adele , Bonoli Alessandra 
Published: March 2022

Abstract
The study focuses on an Italian composting plant and aims to investigate the impact of the presence of plastic impurities in the collected biowaste on the environmental and economic performance of the plant. The study is divided into two main steps: firstly, a material flow analysis was conducted to quantify the number of impurities (e.g., conventional plastics and biodegradable plastics) before and after the composting process. Secondly, a Life Cycle Assessment (LCA) and a complementary Life Cycle Costing (LCC) of the composting process were conducted. The results of the material flow analysis confirmed the initial assumption that conventional plastic remains almost constant before and after the composting treatment, while biodegradable plastic almost disappears. As far as the life cycle analyses are concerned, the most environmentally damaging phases of the process were the shredding and mixing phases, while the operating costs (OPEX) contributed the most to the total annual costs of the company. Finally, a further scenario analysis was performed, assuming that the plastic contaminants in the treated biowaste consisted exclusively of biodegradable plastics. The comparison with this ideal scenario can support decision-makers to understand the potential improvements achievable by addressing the presence of plastic impurities in the biowaste. The results show that the treatment of plastic impurities cause relevant environmental and economic impacts, being responsible for 46% of the total waste to treat at the end of the process, almost 7% of the total annual costs covered by the plant owners and about 30% of all negative externalities.