bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Influence of Moisture Absorption‐Drying of Composite Materials on the Bonding Performance of the Joints
Authors: Chen Chen , Zhang Weirui , Li Yuchen , Gu Lingcong , Luo Yan , Qin Menglan , Zhang Jing , He Zhongjie , Wang Hongni , Zheng Yaping , Yao Dongdong 
Published: October 2022

AbstractComposite materials are susceptible to environmental threats correlated to moisture absorption, which affects the bonding performance of the joints. Therefore, drying should be taken into account during actual manufacturing operations. In this work, the influence of moisture absorption‐drying of composite materials on the bonding performance of the joints is investigated to provide a theoretical direction for the co‐bonding process. Firstly, the surfaces of composite materials are treated with three methods: sanding, dry peel ply, and wet peel ply. Secondly, the composite materials are subjected to moisture absorption‐drying treatment at 26 °C/65% relative humidity (RH) and 70 °C/85% RH. Finally, the above materials are bonded to evaluate the bonding performance. These results show that the bonding performance of the joints treated with two peel plies decreases significantly after moisture absorption. After moisture absorption‐drying at 26 °C/65% RH, the bonding performance of the joints treated with dry peel ply cannot fully recover, while wet peel ply can be fully recoverable. However, the bonding performance of all joints cannot fully recover after absorbing moisture‐drying at 70 °C/85% RH, whose recovery has relations with surface treatment.
Pushforwards of Chow groups of smooth ample divisors, with an emphasis on Jacobian varieties
Authors: Banerjee Kalyan , Iyer Jaya N. N. , Lewis James D. 
Published: October 2022

AbstractWith a homological Lefschetz conjecture in mind, we prove the injectivity of the pushforward morphism on low‐dimensional rational Chow groups, induced by the closed embedding of an ample divisor, namely, the Theta divisor inside the Jacobian variety . Here, C is a smooth irreducible complex projective curve.
CSR preference, market competition, and corporate financial performance
Authors: Deng Dejun , Wu Yi , Qin Linyi 
Published: October 2022

AbstractAlthough the relationship between corporate social responsibility (CSR) and corporate financial performance has been concerned by academia, little is known about how to fulfill CSR. Using a sample of 2111 A‐share public firms in China, this research examines the effects of the way of fulfilling CSR on corporate financial performance and the moderating effects of market competition environments. The results show that firms' CSR behavior of preferred primary stakeholders has a positive effect on corporate financial performance whereas that of preferred secondary stakeholders harms corporate financial performance. Furthermore, this research finds that the stronger the market competition faced by the firm, the more obvious the effect will be, whether it is positive or negative. The findings are helpful to guide the managers on how to better fulfill their CSR, which is of great significance for the sustainable development of CSR.
The early bird catches the worm: The impact of first‐mover advantage on long‐term elite team sport success
Authors: Daumann Frank , Follert Florian , Hamacher Daniel , Plöhn Lasse 
Published: October 2022

AbstractThe research on success factors in elite sport focuses primarily on the one hand to sport in its entirety and on the other hand to the prediction of success in individual sporting events, especially in soccer. In this paper, we investigate the existence of a first‐mover advantage for national team sports, which has a long‐term impact on a nation's success in a sport. To this end, we hand‐collected data for soccer and rugby and analyzed our sample concerning a first‐mover advantage. To do this, we examined the relationship between the date of establishment of each national sports association and later success as measured by the country's world ranking. We check for the essential macro determinants such as GDP per capita and population. Our study shows empirical evidence that the first‐mover advantage has a stronger effect on the success of a state in a team sport than the macro factors mentioned. In this way, we complement previous research on team sports by considering a hitherto neglected effect, a long‐term perspective and by including rugby.
Activation of Calcium‐Sensing Receptor in the Area Postrema Inhibits Food Intake via Glutamatergic and GABAergic Signaling Pathways
Authors: Huang Jinfang , Xu Qian , Li Yuhang , He Xiaoman , Guo Yajie , Sun Xiangrong 
Published: October 2022

ScopeA high‐protein diet has become a popular way to lose weight. Calcium‐sensing receptor (CaSR) is activated by amino acids in addition to calcium ions. CaSR shows dense expression in the area postrema (AP), which participates in feeding regulation. The effect of CaSR in the AP on food intake and the potential mechanism involved is investigated.Methods and resultsMale C57BL/6 mice are used to observe the effect of R568 (agonist of CaSR) on food intake. Enzyme‐linked immunosorbent assay, immunofluorescence staining, and chemogenetics are used to explore the neural signaling involved. CaSR activation in the AP inhibited acute feeding; R568 increases the content of glutamate and γ‐aminobutyric acid (GABA) in the AP, whereas only glutamatergic neurons mediate the effect of R568. GABA‐A receptor and ionic glutamate receptor (N‐methyl‐D‐aspartate receptor [NMDAR]) in the paraventricular nucleus of hypothalamus (PVN) are involved in the effect of R568. Promotion of oxytocin (OT) synthesis in the PVN also participates in the effect of R568, and this mechanism is mediated by NMDAR in the PVN.ConclusionCaSR activation in the AP suppresses feeding, and AP–PVN glutamatergic and GABAergic signaling pathways are involved.
β‐Myrcene Coordination Polymerization: Experimental and Kinetic Modeling Study
Authors: Sá Marília Caroline C. de , Córdova Teresa , Melo Príamo Albuquerque , de León Ramón Díaz , Pinto José Carlos 
Published: October 2022

AbstractThe present work presents phenomenological models to describe the coordination polymerization of β‐myrcene using the Ziegler–Natta catalyst system composed by neodymium versatate (NdV3), diisobutylaluminum hydride (DIBAH), and dimethyldichlorosilane. The kinetic parameters required to simulate the reactions are estimated, and the amount of DIBAH used as a chain transfer agent (CTA) is obtained by a data reconciliation strategy since it can participate in side reactions. Several experiments are performed at different conditions to evaluate the impact of key operation variables on the control of monomer conversion and average molar masses. It is shown that the initial NdV3, β‐myrcene, and DIBAH concentrations exert strong influences on the course of the polymerization. The kinetic mechanism of Coordinative Chain Transfer Polymerization (CCTP) fits well with the data of final average molar masses and monomer conversion, while the dynamic trajectories of these variables are fitted better by kinetic mechanisms of more conventional coordination polymerizations, considering site deactivation and termination by chain transfer. In all cases, the proposed models are able to predict the experimental data well after successful parameter estimation and reconciliation of CTA concentrations, indicating that the kinetic mechanism can be characterized by different kinetic regimes.
Building bespoke exercise: The clinical reasoning processes of physiotherapists when prescribing exercise for persons with musculoskeletal disorders
Authors: Grimus Johanna , Horler Christopher , Hebron Clair 
Published: October 2022

AbstractAimsThis qualitative study aimed to explore physiotherapists' clinical reasoning when prescribing exercise for persons with musculoskeletal disorders.MethodsA constructivist grounded theory inspired methodological approach was used. Six physiotherapists working in the United Kingdom were recruited via purposive sampling. Data collection and analysis included semi‐structured interviews, memo writing, coding, and a constant comparative method.FindingsA concept of ‘building bespoke exercise’ has been generated to conceptualise the participants' clinical reasoning when prescribing exercise.ConclusionThe findings of this study highlight processes of co‐designing and co‐constructing exercise programmes in collaboration with persons receiving care. Physiotherapists can use this study to reflect on their own clinical reasoning to inform their own practice.
Modelling hydraulic and capillary‐driven two‐phase fluid flow in unsaturated concretes at the meso‐scale with a unique coupled DEM‐CFD technique
Authors: Krzaczek Marek , Nitka Michał , Tejchman Jacek 
Published: October 2022

AbstractThe goal of the research was to demonstrate the impact of thin porous interfacial transition zones (ITZs) between aggregates and cement matrix on fluid flow in unsaturated concrete caused by hydraulic/capillary pressure. To demonstrate this impact, a novel coupled approach to simulate the two‐phase (water and moist air) flow of hydraulically and capillary‐driven fluid in unsaturated concrete was developed. By merging the discrete element method (DEM) with computational fluid dynamics (CFD) under isothermal settings, the process was numerically studied at the meso‐scale in two‐dimensional conditions. A flow network was used to describe fluid behaviour in a continuous domain between particles. Small concrete specimens of a simplified particle mesostructure were subjected to fully coupled hydro‐mechanical simulation tests. A simple uniaxial compression test was used to calibrate the pure DEM represented by bonded spheres, while a permeability and sorptivity test for an assembly of spheres was used to calibrate the pure CFD. For simplified specimens of the pure cement matrix, cement matrix with aggregate, and cement matrix with aggregate and ITZ of a given thickness, DEM/CFD simulations were performed sequentially. The numerical results of permeability and sorptivity were directly compared to the data found in the literature. A satisfactory agreement was achieved. Porous ITZs in concrete were found to reduce sorption by slowing the capillary‐driven fluid flow, and to speed the full saturation of pores when sufficiently high hydraulic water pressures were dominant.
Recovery from weight regain among long‐term weight loss maintainers in WW
Authors: Hayes Jacqueline F. , Wing Rena R. , Phelan Suzanne , Alarcon Noemi , Cardel Michelle I. , Foster Gary D. 
Published: October 2022

AbstractObjectiveThis study sought to understand the process and strategies to recover from regain among weight loss maintainers.MethodsParticipants in WeightWatchers (WW; n = 2457) had lost ≥9 kg for ≥1 year and were grouped based on self‐reported weight change after maximum loss: sustained maintenance (“Stable”), ups and downs (“Gain–Lose”), and regain (“Gain”). The groups were compared on weight control strategies, and the Gain–Lose and Gain groups reported on attempts to reverse weight regain.ResultsMean weight loss was 28.5 kg and duration of ≥9 kg loss was 3.5 years. During this time, 48% reported weight stability, and the remaining reported some regain (Gain–Lose, 29% or Gain, 23%). Among Gain and Gain–Lose, action to lose regained weight occurred after gaining >4 kg. Compared with Gain, Gain–Lose sustained reengagement efforts longer (16 vs. 10 weeks) and had better dietary choices (3.4 vs. 3.2), self‐monitoring (2.9 vs. 2.7), and psychological coping (2.5 vs. 2.4) scores. Among Gain–Lose, the most successful (< 2.3 kg vs. >2.3 kg regain) initiated weight loss efforts after less regain (2.3 vs. 4.5 kg).ConclusionsReengaging with weight loss after regains may be most successful if focused on diet, self‐monitoring, and psychological coping and initiated with less regain.
Static and dynamic mechanical behavior of intra‐hybrid jute/sisal and flax/kenaf reinforced polypropylene composites
Authors: Kaushik Deepak , Gairola Sandeep , Varikkadinmel Binaz , Singh Inderdeep 
Published: October 2022

AbstractThe current experimental investigation examines the effect of the warp/weft orientation of jute/sisal and flax/kenaf fibers on the static and dynamic mechanical characteristics of intra‐woven hybrid composites. Jute (J), sisal (S), flax (F), and kenaf (K) hybrid woven mats were explicitly designed to keep fibers in the warp and weft directions. Intra‐hybrid‐composites with JJ, JS, SJ, SS, FF, FK, KF, and KK type hybrid woven mats with polypropylene matrix were processed using the compression molding/film stacking method. The tensile and flexural, and the dynamic mechanical behavior was investigated. Utilizing a scanning electron microscope, the fractured surface of tensile test specimens was examined. The results indicate that combining jute with sisal and flax with kenaf improved the mechanical properties of pure sisal and kenaf based composites. Hybridized composites exhibited the maximum increment in tensile strength (5.95% and 31.16%), tensile modulus (4.20% and 66.64%), flexural strength (12.59% and 5.69%), and flexural modulus (47.10% and 19.72%) for JS and FK composites, when compared with unhybridized SS and KK composites, respectively. The fiber hybridization and warp/weft sequence have a substantial effect on the dynamic mechanical performance of woven fiber laminated composites. It was identified that composites of JS and FK possess a higher storage modulus than pure SS and KK based composites, respectively. In addition, at a temperature of 50°C, the storage modulus was improved by 37.63% and 136.63%, for JS and FK hybrid composites, respectively in comparison to the unhybridized SS and KK composites, respectively.
Strategy for the quality control of herbal preparations made of Sarcocephalus latifolius: Development and validation of a UHPLC‐PDA method for quantification of angustoline and strictosamide and chemical profiling using LC‐QToF
Authors: Tittikpina Nassifatou Koko , Katragunta Kumar , Avula Bharathi , Ali Zulfiqar , Khan Ikhlas A. 
Published: October 2022

AbstractIntroductionSarcocephalus latifolius is one of the most used plants in West African traditional medicine to treat malaria.ObjectiveThe aim is to establish a strategy to control the quality of herbal preparations made from S. latifolius.MethodA UHPLC‐PDA method was developed for the determination and quantification of the two main bioactive compounds (angustoline and strictosamide) in various parts of the plant. Additionally, an LC‐QToF with electrospray ionization method is described for the identification and confirmation of compounds in samples of different parts of the plant.ResultsWith the UHPLC‐PDA method, separation was achieved within 5 min using a C18 column stationary phase at a temperature of 45°C and a gradient system with a mobile phase of water and acetonitrile, both containing 0.1% formic acid. The method was validated for linearity, accuracy, precision (repeatability and intermediate precision), limit of detection (LOD), and limit of quantification (LOQ). The LOD and LOQ of angustoline were found to be 0.3 and 0.8 μg/ml, respectively, and those of strictosamide were found to be 0.1 and 0.3 μg/ml, respectively. Using the LC‐QToF method, 90 secondary metabolites, including four isolated compounds from the plant's roots, were identified from leaf, bark, and root samples of S. latifolius.ConclusionThis work is the first to propose a strategy to control the quality of herbal preparations made from S. latifolius. The developed method allows the quantification of the main bioactive compounds and the established chemical profile allows to distinguish the plant from any other species.
18F‐DCFPyL positron emission tomography/magnetic resonance imaging‐guided ultrasound fusion biopsy is an identical pathway in prostate cancer diagnosis
Authors: Niu Shaoxi , Liu Yachao , Ding Xiaohui , Xu Yong , Yu Hongkai , Feng Xiaodong , Chang Xiao , Wang Haiyi , Li Jinhang , Gong Huijie , Ao Liyan , Liu Jiajin , Lin Mu , Wang Baojun , Ma Xin , Xu Baixuan , Zhang Xu 
Published: October 2022

AbstractBackgroundProstate biopsy is still unavoidable in patients with a rising prostate‐specific antigen even though multiparametric magnetic resonance imaging (MRI) is widely used. 18F‐DCFPyL positron emission tomography (PET)/MRI was proved to be promising both in sensitivity and specificity. But its guiding fusion biopsy and the advantages in the diagnosis of prostate disease is seldom reported. This study aimed to verify the feasibility and advantage of 18F‐DCFPyL PET/MRI‐guided fusion targeted biopsy (TB) over whole‐mount histopathology (WMH) for prostate cancer diagnosis.MethodsA prospective study of 94 biopsy‐naïve patients were conducted using 18F‐DCFPyL PET/MRI scans and scored on a scale of 1–4. Systematic biopsy was performed for all patients. Patients with suspicious lesions also underwent PET/MRI/transrectal ultrasound‐guided fusion biopsy. Patients with pathologically confirmed cancer underwent surgery and WMH sections. Systematic biopsy was compared with TB for the detection of index tumors (ITs). Significant cancer was defined as Grade group (GG) 2 or higher no matter the length of the cancer core.Results18F‐DCFPyL PET/MRI detected 30/94 (32%) patients with a score of 4, all of whom were verified to have prostate cancer. While it detected 10 patients with a score of 1 (10.6%), they were shown to have no cancer. The sensitivity and specificity of 18F‐DCFPyL PET/MRI were 94.4% and 75%, respectively, if images with a score of 3 are defined as positive. Systematic biopsy detected 18% (203/1128) samples as prostate cancer; conversely, TB detected 113 samples out of 259 scores (43.6%). A statistically significant difference was seen between the PCa detection rates by TB and SB (p < 0.001). All targeted lesions were pathologically proven to be the IT on WMH.ConclusionsIn biopsy‐naïve patients, the ultrasound fusion biopsy targeted by 18F‐DCFPyL PET/MRI is an identical pathway for the detection of prostate cancer.
Quantitative systems pharmacology model of the amyloid pathway in Alzheimer's disease: Insights into the therapeutic mechanisms of clinical candidates
Authors: Ramakrishnan Vidya , Friedrich Christina , Witt Colleen , Sheehan Robert , Pryor Meghan , Atwal Jasvinder K. , Wildsmith Kristin , Kudrycki Katherine , Lee Seung‐Hye , Mazer Norman , Hofmann Carsten , Fuji Reina N. , Jin Jin Y. , Ramanujan Saroja , Dolton Michael , Quartino Angelica 
Published: October 2022

AbstractDespite considerable investment into potential therapeutic approaches for Alzheimer's disease (AD), currently approved treatment options are limited. Predictive modeling using quantitative systems pharmacology (QSP) can be used to guide the design of clinical trials in AD. This study developed a QSP model representing amyloid beta (Aβ) pathophysiology in AD. The model included mechanisms of Aβ monomer production and aggregation to form insoluble fibrils and plaques; the transport of soluble species between the compartments of brain, cerebrospinal fluid (CSF), and plasma; and the pharmacokinetics, transport, and binding of monoclonal antibodies to targets in the three compartments. Ordinary differential equations were used to describe these processes quantitatively. The model components were calibrated to data from the literature and internal studies, including quantitative data supporting the underlying AD biology and clinical data from clinical trials for anti‐Aβ monoclonal antibodies (mAbs) aducanumab, crenezumab, gantenerumab, and solanezumab. The model was developed for an apolipoprotein E (APOE)ɛ4allele carrier and tested for anAPOE ɛ4noncarrier. Results indicate that the model is consistent with data on clinical Aβ accumulation in untreated individuals and those treated with monoclonal antibodies, capturing increases in Aβ load accurately. This model may be used to investigate additional AD mechanisms and their impact on biomarkers, as well as predict Aβ load at different dose levels for mAbs with known targets and binding affinities. This model may facilitate the design of scientifically enriched and efficient clinical trials by enabling a priori prediction of biomarker dynamics in the brain and CSF.
Reducing the acknowledgement frequency in IETF QUIC
Authors: Custura Ana , Jones Tom , Secchi Raffaello , Fairhurst Gorry 
Published: October 2022

SummarySatellite networks usually use in‐network methods (such as Performance Enhancing Proxies for TCP) to adapt the transport to the characteristics of the forward and return paths. QUIC is a transport protocol that prevents the use of in–network methods. This paper explores the use of the recently–standardised IETF QUIC protocol with a focus on the implications on performance when using different acknowledgement policies to reduce the number of packets and volume of bytes sent on the return path. Our analysis evaluates a set of ACK policies for three IETF QUIC implementations, examining performance over cellular, terrestrial and satellite networks. It shows that QUIC performance can be maintained even when sending fewer acknowledgements, and recommends a new QUIC acknowledgement policy that adapts QUIC's ACK Delay value based on the path RTT to ensure timely feedback. The resulting policy is shown to reduce the volume/rate of traffic sent on the return path and associated processing costs in endpoints, without sacrificing throughput.
Journey from cloud of things to fog of things: Survey, new trends, and research directions
Authors: Chakraborty Ananya , Kumar Mohit , Chaurasia Nisha , Gill Sukhpal Singh 
Published: October 2022

AbstractWith the advent of the Internet of Things (IoT) paradigm, the cloud model is unable to offer satisfactory services for latency‐sensitive and real‐time applications due to high latency and scalability issues. Hence, an emerging computing paradigm named as fog/edge computing was evolved, to offer services close to the data source and optimize the quality of services (QoS) parameters such as latency, scalability, reliability, energy, privacy, and security of data. This article presents the evolution in the computing paradigm from the client‐server model to edge computing along with their objectives and limitations. A state‐of‐the‐art review of Cloud Computing and Cloud of Things (CoT) is presented that addressed the techniques, constraints, limitations, and research challenges. Further, we have discussed the role and mechanism of fog/edge computing and Fog of Things (FoT), along with necessitating amalgamation with CoT. We reviewed the several architecture, features, applications, and existing research challenges of fog/edge computing. The comprehensive survey of these computing paradigms offers the depth knowledge about the various aspects, trends, motivation, vision, and integrated architectures. In the end, experimental tools and future research directions are discussed with the hope that this study will work as a stepping‐stone in the field of emerging computing paradigms.
Synthesis and crystal structure of the first ternary tellurium borate TeB4O8
Authors: Ziegler Raimund , Heymann Gunter , Huppertz Hubert 
Published: October 2022

AbstractMonoclinic TeB4O8 was obtained in a Walker‐type multianvil apparatus at 10 GPa and 1273 K from TeO2 and B2O3. It crystallizes isotypically to the compounds AnB4O8 (An=Th, U) in the space group C2/c (Z=4) with the lattice parameters a=15.6978(8) Å, b=4.2284(2) Å, c=7.4305(4) Å, β=114.78(1)°, and V=447.80(4) Å3. Further, it has been characterized via X‐ray diffraction experiments and IR spectroscopy.