bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trends in the Environment Design of IT Centers in the Conditions of the Coronavirus Pandemic
Authors: Semyroz Nina , Lopukhova Natalia , Klivak Myroslavа 
Published: May 2022

The purpose of the article is to identify the features of the formation of IT centers’ environment, following the trends of decoration in the context of the coronavirus pandemic. As well as, to predict, and determine changes in the methodological basis for the creation of the interior environment of IT centers through design in terms of protecting the population from the coronavirus pandemic. The research methodology is based on the use of methods of generalization and systematization of scientific and theoretical information on environmental design in the context of the spread of coronavirus infection, as well as analysis of domestic and foreign experience in designing the object of study. The scientific novelty of the study is to clarify and systematize the basic techniques and features of interior solutions formation of IT centers in the context of protection against coronavirus infections. Conclusions. An activity office is a flexible workspace that provides employees with a variety of jobs, and they can use this space according to the tasks assigned to them. Trends in the environment design of IT centers in the context of the coronavirus pandemic are actively formed and disseminated among production managers and designers. The main priorities of the design are the safety of workers while maintaining their psychological comfort and efficiency, environmental friendliness, aesthetics, and the use of innovative materials and technologies. We consider the following to be the most effective design techniques: zoning a large room with the help of mobile transparent partitions or individual closed capsules for workers while reducing the size of the work area per person; the use of the method of “hot desking”, in which the space remains open, increases the size of the work area per person, but reduces the number of people who are in the office at the same time; introduction of contactless systems for passing between rooms and calling elevators (use of voice control devices with a speaker; smartphone, smartwatch, face recognition systems); installation of engineering structures for ventilation and disinfection of surfaces, which should be beaten by aesthetic design; application in coverings of walls, ceilings, and floors of rooms, and also surfaces of furniture of materials and technologies of antiviral cleaning.
Infection control and safety protocols used during the pandemic are becoming the standard for new projects by designers and architects. Thus, the pandemic marked the beginning of a new era in office interior design.
PENATALAKSANAAN FISIOTERAPI KONDISI FROZEN SHOULDER e.c TENDINITIS MUSCLE ROTATOR CUFF DENGAN MODALITAS SHORT WAVE DIATHERMY, ACTIVE RESISTED EXERCISE DAN CODMAN PENDULAR EXERCISE
Authors: Putri Anggun Rahmawati , Wulandari Irine Dwitasari 
Published: May 2022

<p><strong>Background: </strong>Frozen shoulder is a pain in shoulders which conduces limitedness of shoulder joint motion. Tendinitis in M.Rotator Cuff, is an inflammation occured in muscle tendons fused in Rotator Cuff. Physiotherapy problematics of Frozen Shoulder are the existence of pain, the limitedness of joint motion, the decline of muscle strength, and the interference of functional activity. Physiotherapy examination includes examining pain with Verbal Descriptive Scale (VDS), examination of Limited Range Of Motion with Goneometer, examination of muscle strength with Manual Muscle Testing (MMT), and inspection of daily functional activities with the Shoulder Pain And Disability Index (SPADI) index. In this case, the chosen technology to resolve these problems are by using the modality of Short Wave Diathermy (SWD), Active Resisted Exercise and Codman Pendular Exercise.</p><p><strong>Objective: </strong>To know the effect of Physiotherapy Management Frozen Shoulder e.c Tendinitis Muscle Rotator Cuff conditions with Short Wave Diathermy (SWD), Active Resisted Exercise and Codman Pendular Exercise.</p><p><strong>Methods: </strong>This research was done in RSUD Kraton Pekalongan with analytic descriptive research design. Research subject in this Scientific Writing was a patient with Frozen Shoulder condition e.c. Tendinitis M.Rotator Cuff who was given physiotherapy interventions with the modality of Short Wave Diathermy (SWD), Active Resisted Exercise and Codman Pendular Exercise. Method of data collection and data analysis of this research were by using Autoanamnesis method. Research instruments consisted of the examination of pain, joint motion, muscle strength, and potentiality of functional activity.</p><p><strong>Result:</strong> After four times in therapy, the researcher got four result. They are there was a decline of force pain in T3 = 3 and motion pain in T2 = 2, there was an enhancement of joint motion in T3 and T4 in flexion movement, abduction, exorotation and endorotation of the left shoulder to active and passive movement, there was an enhancement of muscle strength in T3 = Muscle group exorotator and endorotator, and there was an enhancement of functional activity in T3.</p><p><strong>Conclution:</strong> a physiotherapy intervention with device modality and therapeutic exercise modality of can help reduce the problems arising on the conditions of Frozen Shoulder.</p><strong>Keywords :</strong> <em>Frozen Shoulder e.c Tendinitis M.Rotator Cuff, Short Wave Diathermy (SWD), Active </em><em>Resisted Exercise and Codman Pendular Exercise, Autoanamnesis Method, Indeks SPADI (Shoulder Pain And Disability Index)</em>
The effect of Lycium barbarum on reproductive system and the expression of CRISP-1 protein in experimentally diabetic male rats
Authors: İLTER AKTAŞ Gizem , FIRAT Tülin , PEHLİVAN KARAKAŞ Fatma 
Published: May 2022

Aim: The main purpose of this study is to investigate the effects of Lycium barbarum polysaccharides (LBP) on the male reproductive system and Crisp-1 protein expression in experimentally diabetic Wistar Albino male rats.
Material and Method: In this study Wistar Albino male rats (3-4 months old) were randomly selected and divided into four groups; Control, LBP control (only LBP), Diabetic and Treatment (diabetic + LBP) group. For the experimental diabetes model, a single dose of 55 mg/kg STZ was injected intraperitoneally. In the treatment group, the diabetic rats were administered with 200 mg/kg of LBP by gastric gavage for 15 consecutive days.
Results: In histological examinations, increased intertubular connective tissue, congestion, vacuolization and edema were observed in testicular tissues of the diabetic group. The histopathological changes were improved after LBP treatment. Also, the number of total sperm count and sperm motility were significantly increased in the treatment group. Our biochemical analysis results showed that the serum testosterone level were significantly increased and serum MDA level were significantly decreased after treatment with LBP. Compared to the diabetic group, the apoptotic cells were decreased in the treatment group. Crisp-1 protein expression was increased in the treatment group, Crisp-1 possitive vesicle-like structures and apical blebs were also examined in the epididymal tissues.
Conclusion: It is concluded that Lycium barbarum polysaccharides have a therapeutic effect on the male reproductive damages of diabetes and also enhances Crisp-1 protein expression in the epididymis.
Evaluation of the need for hospital-based pediatric palliative care in a single center
Authors: DURMAZ Nihal , ÖZTELCAN GÜNDÜZ Bahar , ATAS Erman 
Published: May 2022

Introduction/Aim: Cancer is one of the leading causes of death for children . Evidence suggests that these children experience substantial suffering from physical and emotional symptoms. Over the past two decades, paediatric palliative care has emerged as an approach that aims to ease suffering for children and their families coping with any life-threatening illness. Our aim is to encourage the expansion of palliative care centers for children with cancer and integration of these into healthcare services to assist clinicians and policy makers in developing services that address these needs.
Material and Method: Our study is a single-center retrospective cohort study. The records of 39 patients who were followed up in the pediatric oncology clinic between 2010-2021 and died were reviewed retrospectively.
Results: The age of diagnosis of patients was the most in the 6-12 range (n=16; 41%) and the least in the adolescent (n=11; 28.2%) age range. The cause of death was related to a disease in 79.5%. Treatment-related deaths were seen in eight patients, four of which were chemotherapy toxicity, two were engraftment failure in autologous hematopoietic stem cell transplantation, and two were post-transplant GVHD. 76.9% of the patients died in the intensive care unit.
Conclusion: In our study, patients with cancer and those who lost their lives were evaluated retrospectively in terms of symptom load, invasive procedures, and psychosocial needs and the need for end-of-life palliative care. Many studies have confirmed that the timely integration of palliative care into routine oncological care has many advantages, such as improvements in physical and psychological symptoms, quality of life and prognosis, as well as reducing costs. In Turkey, palliative treatment is tried to be provided to late stage pediatric cancer patients by pediatric intensive care units and pediatric oncologists. This both increases the workload of physicians and causes intensive care bed occupation. The development and expansion of palliative care on late stage pediatric cancer patients will contribute significantly to the quality of life of both children and their families.
Relationship between the amniotic fluid prolactin level at early second trimester and pregnancy outcome
Authors: ŞİRİNOĞLU Hicran , ÖZDEMİR Savaş , GÖKÇER Oya , GENÇ Simten , EMEKLİOGLU Cagdas Nurettin , ÖZKAYA Enis 
Published: May 2022

Aim: The aim of this study was to determine whether early second trimester amniotic fluid prolactin level were associated with pregnancy outcome.
Material and Method: This study included 125 women who underwent amniocentesis for variable indications. Healthy subjects with no history of drug use were included in this study. The gestational age was determined by ultrasonic examination before 10 weeks in all cases. Amniotic fluid specimens were taken while performing amniocentesis for other indications. Amniotic fluid was collected by transabdominal amniocentesis. Amniotic fluid prolactin concentrations were utilized to predict pregnancy complication among women who underwent amniocentesis due to the variable indications.
Results: Among all study population, pregnancy was unremarkable in 102 (81.6%) cases, on the other hand, most common fetal abnormality was found to be the fetal hydrops fetalis and the second most commonly encountered fetal anomaly was trisomy, intrauterine growth restriction and intrauterine fetal demise. All study population was divided into two groups as complicated (n=23) and uncomplicated (n=102) pregnancies. Amniotic fluid prolactin concentration did not have any predictive value for complicated pregnancies (AUC=0.479).
Conclusion: Our data showed; there is no relationship between early second trimester amniotic fluid prolactin level and pregnancy outcome.
The effect of main pulmonary artery diameter on the prognosis of COVID-19 patients in the ICU
Authors: ÇORAPLI Gökhan , ÇİL Ercan , ŞAHİN TUTAK Ayşe , ÇORAPLI Mahmut 
Published: May 2022

Aim: The aim of this study was to examine the effect of main pulmonary artery diameter (MPAD), which is evaluated in patients when first admitted to the intensive care unit due to COVID-19, on mortality.
Material and Method: Thoracic computed tomography examinations performed during the initial admission to hospital of patients who were treated in the intensive care unit between October 1, 2020, and June 1, 2021, were evaluated retrospectively. Cox regression analysis was performed with the program R-Project to evaluate the relationship between MPAD and mortality.
Results: No significant correlation was found between MPAD and mortality in models used with or without adjusting for age and sex (respectively P: 0.890 and P: 0.920).
Conclusion: The MPAD value measured at the initial admission of COVID-19 patients hospitalized in the intensive care unit is not a parameter that can be used to predict mortality.
Evaluation of anatomical variations with morphological measurements and their relationship with rotator cuff tear and acromion types
Authors: ÖNCÜ Süleyman , ARSLAN Fatma Zeynep , KÖREZ Muslu Kazım 
Published: May 2022

Introduction: There many more anatomical measurements such as the acromiohumeral distance and lateral acromion angle and acromial configuration was reported as might be associated with rotator cuff tear. In our study, we aimed to reveal the effect of acromion index, acromiohumeral distance, lateral acromion angle, critical shoulder angle values and the acromion type in the development of rotator cuff tear.
Material and Method: In our retrospective study, 58 patients and 29 asymptomatic volunteers who underwent shoulder magnetic resonance imaging examinations were examined. acromion index, acromion humaral distance, lateral acromion angle and critical shoulder angle were measured and their relationship with rotator cuff tear and acromion types were evaluated.
Results: Type III (hooked) of acromial shapes, higher acromion index and critical shoulder angle values, lower acromiohumeral distance and lateral acromion angle values are more frequently seen in rotator cuff tear patients, in our study.
Conclusion: Thus, we revealed anatomical malformations that predispose to rotator cuff tear concerning the shoulder joint.
Clinical value of heart type fatty acid binding protein (H-FABP) in acute pulmonary thromboembolism
Authors: ALTUĞ Tuba , ŞENTÜRK Ayşegül , ALIŞIK Murat , BİÇER Cemile 
Published: May 2022

Introduction: To investigate factors which could possibly be prognostic, to decide on thrombolytic therapy as soon as possible, and to determine the prognostic value of H-FABP, which is a new marker, in pulmonary thromboembolism.
Material and Method: In our study, a patient group, consisting of 58 patients diagnosed with PTE and a control group of 30 healthy individuals were investigated. According to their risk of mortality, patients were analyzed in three groups: high, moderate and low. The moderate mortality risk groups were categorized into two groups according to PAP and patients with PAP≥45 mmHg were “Group 1” and PAP
Pneumococcal and influenza vaccination rates among patients with cardiovascular disease
Authors: ERDEM Kenan , DUMAN Ipek , KIZMAZ Muhammet , İLGENLİ Tevfik Fikret 
Published: May 2022

Introduction: Influenza virus infections and pneumococcal pneumonia are associated with significant increases in hospitalization and mortality rates in patients with cardiovascular diseases (CVD). In Turkey, pneumococcal and flu vaccines are recommended for patients with chronic heart disease, adults aged 65 and older and adults who are at risk of pneumonia.
Material and Method: This study was conducted between July 2019 and December 2019 among 240 CVD patients. The survey consisted of 29 questions aimed at evaluating the sociodemographic characteristics of the patients, the history of influenza and pneumococcal vaccines, and their knowledge and attitudes towards vaccines.
Results: Vaccination rates were low in CVD patients. Last year, only 10% of the participants had been previously vaccinated with the pneumococcal vaccine and 27.75% with the influenza vaccine. While the percentage of vaccination influenza vaccine among university graduates was significantly higher than all other groups, this high was not detected for pneumococcal vaccine.
Eighty percent of the participants visited their family physicians regularly in the previous year, while only 61.6% received information about the vaccination from the doctor or nurse. Influenza vaccine (39.2%) was recommended at a higher rate than pneumococcal pneumonia (12.1%) by the physicians or nurses of the participants during the visits. (p
Is there an association between thyroid function tests and 18F FDG PET/CT parameters in untreated cancer patients?
Authors: KAPLAN İhsan , CAN Canan , KÖMEK Halil , KEPENEK Ferat , SOYLU Hikmet , ERDUR Erkan , AGÜLOĞLU Nurşin , GÜNDOĞAN Cihan 
Published: May 2022

Objectives: We aimed to investigate the association between the extent of disease, 18F FDG PET/CT parameters (SUVmax and the highest SUVmax) and thyroid function tests (TFT) (TSH, FT4, FT3, FT3/FT4 ratio, AntiTG, and AntiTPO) in untreated cancer patients.
Material and Method: One hundred and seventy-nine patients who underwent FDG PET/CT for metabolic characterization and staging in our clinic between May 2020 and November 2020 were included in the study. Patients were divided into two groups as malignant and benign according to histopathology findings. Thyroid function tests were ordered from all patients at the time of PET/CT imaging. The association between the presence of local lymph node metastasis, distant metastases and thyroid function tests as well as the association between PET/CT parameters and thyroid function tests in benign and malignant groups were statistically analyzed.
Results: Thyroid function tests did not exhibit a significant difference between patients with malignant and benign disease (p> 0.05). Univariate logistic regression analysis revealed that age, FT4 value, and the FT3/F4 ratio were significant parameters in predicting distant metastases. These parameters were also significant in predicting mortality. Multivariate logistic regression analysis showed that age was an independent prognostic factor predicting mortality.
Conclusion: Thyroid function tests are not decisive in differentiating malignant and benign lesions. While no statistically significant correlation was observed between thyroid function tests and PET/CT parameters, univariate analyses revealed that especially FT4 and FT3/FT4 ratio were significant in predicting disease extent and mortality in malignant disease. Age was found to be an independent prognostic factor in predicting mortality.
Evaluating the influence of 6MV and 10MV photon beams on cervical cancer volumetric-modulated arc therapy plans
Authors: He Dong-Cheng , Zhu Zhi-Jian , Zhang Xiao-Ye , Zhang Yan , Hong Jun , Shi Ting-Ting , Han Ji-Hua 
Published: May 2022

BACKGROUND: Cervical cancer is a common gynecological cancer among women worldwide. OBJECTIVE: To determine the effects of 6 MV and 10 MV volumetric-modulated arc therapy (VMAT) photon beams on the target volume (TV) planning and critical organs in cases of cervical cancer. METHODS: Fifty patients with carcinoma of the cervix who underwent radiotherapy were selected. The transverse diameter (T) of the cross section of the upper edge of the sacroiliac joint on computerized tomography (CT) images of the patients was measured, and the mean value was calculated as 34 cm. All patients were divided into two groups: Group A (T < 34 cm) and Group B (T > 34 cm). The VMAT plans were generated using 6 MV and 10 MV plans separately. The prescription dose was 47.5 Gy, and the daily dose was 1.9 Gy. RESULTS: In Group A, the planning target volume (PTV) dose assessment parameters of 6 MV and 10 MV plans and their homogeneity and conformity indices were not statistically significantly different. A significant difference was observed between the 6 MV and 10 MV plans for the PTV dose assessment parameters and the homogeneity index of the plans for Group B. The monitor units (MUs) of the 10 MV plans were lower than in the 6 MV plans in both Groups A and B, and the difference was statistically significant. The assessment parameter V40 Gy of both the rectum and bladder in the 6 MV plans was smaller than the corresponding parameter in the 10 MV plans in Group A; in Group B, the assessment parameter V50 Gy of the rectum in the 10 MV plans was smaller than in the 6 MV plans. CONCLUSION: When T < 34 cm, 6 MV energy is more suitable for the external irradiation of cervical cancer. When T > 34 cm, 10 MV energy is more suitable for cervical cancer radiotherapy. Therefore, 10 MV should be considered for patients with a large abdominal size.
Perspectives on the Immune System in Sepsis
Authors: Stancioiu Felician , Ivanescu Bogdan , Dumitrescu Radu 
Published: May 2022

Beyond the modifications shown by the biochemistry labs, profound and ample modifications are seen in septic patients at a molecular level stemming from DNA translation and gene expression, manifested as unique profiles of mRNA (messenger), as well as non-coding, functional RNAs: miRNA (micro) and lncRNAs (long non-coding). Counteracting these modifications requires treatement with pleiotropic molecules and/or combination of molecules and opens the possibility of future treatments with arrays of siRNAs and/or specific panels of small molecules tailored for each patient subpopulation.
DIGITAL MARKETING STRATEGY OF KARIKSA KEBUNKU DURING THE COVID-19 PANDEMIC WITH A BUSINESS MODEL CANVAS (BMC) APPROACH
Authors: Manalu Doni Sahat Tua , Nurlatifah Sapti , Sarahsati Febrya 
Published: May 2022

Kariksa Kebunku adalah salah satu perusahaan dalam bidang budidaya bunga mawar potong yang terletak di Lembang Bandung Barat. Pada umumnya sebelum terjadi pandemi Covid-19 permintaan bunga mawar potong banyak digunakan pada acara-acara pernikahan, dekorasi, wisuda, hari valentine dan beberapa acara lainnya dan puncak dari tingginya permintaan bunga mawar di Kariksa Kebunku adalah bulan Februasi akan tetapi pada saat pandemi Covid-19 usaha bunga mawar di Kariksa Kebunku mengalami penurunan penjualan. Dengan demikian, Kariksa Kebunku perlu memanfaatkan perkembangan teknologi informasi berupa digital marketing dengan merubah sistem pemasaran untuk melakukan promosi dan pemasaran bunga mawar potong dalam rangka menjangkau pasar yang lebih luas dimasa pandemi Covid-19. Salah satu metode analisis yang dapat digunakan untuk pengembangan bisnis adalah pendekatan Business Model Canvas (BMC). Tujuan penelitian menganalisis strategi digital marketing yang dapat diterapkan sebagai salah satu alternatif pengembangan dan solusi terhadap permasalahan di Kariksa Kebunku pada masa pandemi Covid-19 dengan pendekatan Business Model Canvas (BMC). Adapun metode pengumpulan data yaitu pemilihan lokasi penelitian dilakukan secara sengaja (purposive) karena Kariksa Kebunku adalah salah satu usaha yang bergerak dalam bidang tanaman mawar dan terdampak pandemi Covid-19. Data yang digunakan adalah jenis data primer dan sekunder. Penentuan strategi pemasaran dilakukan dengan pendekatan Business Model Canvas (BMC). Hasil penelitian diperoleh berdasarkan sembilan elemen BMC yang terdiri dari customer segments, value proposition, channels, customer relationships, revenue streams, key resources, key activities, key partnerships, dan cost structure yang terangkum dalam satu kanvas menunjukkan bahwa penerapan digital marketing mampu meningkatkan pendapatan yang memberikan keuntungan bagi Kariksa Kebunku pada masa pandemi Covid-19.