bluuebunny/crossref_metadata_2025_split huggingface dataset:
How do UK general practice staff understand and manage prediabetes? A focus group study
Authors: Barry Eleanor , Greenhalgh Trisha 
Published: May 2022

BackgroundPreventing type 2 diabetes is a national priority; one aspect is the identification and active management of ‘prediabetes’ through lifestyle change.AimTo explore what primary care clinicians understood by ‘prediabetes’, how they communicated this diagnosis to people, how they delivered lifestyle advice, and their views on barriers to lifestyle change.Design & settingThree focus groups were undertaken with 25 individuals from primary care teams (GPs, nurses, and healthcare assistants) in Newham, a deprived and ethnically diverse part of London, UK.MethodRecordings were transcribed verbatim and analysed thematically before integrating social and behavioural science theories.ResultsFocus groups participants described four main influences on their management of prediabetes in the consultation: social determinants, clinical aspects of diagnosis and management, patient motivation and behaviour change, and long-term care. Since most felt unable to address social determinants such as poverty, discussions with patients tended to focus on attempts to change individual behaviours and achieve particular numerical targets, with limited attention to the social context in which behaviours would play out.ConclusionType two diabetes prevention efforts in general practice may fail to address the upstream causes of this disease. A narrow focus on numerical targets and decontextualised behaviours overlooks the social complexity of human behaviour and lifestyle choices. Within the consultation, the authors recommend that greater attention is paid to discussing the social context and meaning of particular behaviours. Beyond the consultation, collaboration between primary care clinicians, public health bodies, and local governments is required to address community-level constraints to behaviour change.
Stromal Transcription Factor 21 Regulates Development of the Renal Stroma via Interaction with Wnt/β-Catenin Signaling
Authors: Finer Gal , Maezawa Yoshiro , Ide Shintaro , Onay Tuncer , Souma Tomokazu , Scott Rizaldy , Liang Xiaoyan , Zhao Xiangmin , Gadhvi Gaurav , Winter Deborah R. , Quaggin Susan E. , Hayashida Tomoko 
Published: May 2022

Key Points

Transcription factor 21 in Foxd1+ interstitial progenitors is required for proliferation and differentiation of the renal stroma.Tcf21 binds to β-catenin and enhances expression of stromal Wnt target genes.The kidney stroma is critical for normal development of the nephron progenitor cells, loop of Henle, and collecting ducts.

Background
Kidney formation requires coordinated interactions between multiple cell types. Input from the interstitial progenitor cells is implicated in multiple aspects of kidney development. We previously reported that transcription factor 21 (Tcf21) is required for ureteric bud branching. Here, we show that Tcf21 in Foxd1+ interstitial progenitors regulates stromal formation and differentiation via interaction with β-catenin.

Methods
We utilized the Foxd1Cre;Tcf21f/f murine kidney for morphologic analysis. We used the murine clonal mesenchymal cell lines MK3/M15 to study Tcf21 interaction with Wnt/β-catenin.

Results
Absence of Tcf21 from Foxd1+ stromal progenitors caused a decrease in stromal cell proliferation, leading to marked reduction of the medullary stromal space. Lack of Tcf21 in the Foxd1+ stromal cells also led to defective differentiation of interstitial cells to smooth-muscle cells, perivascular pericytes, and mesangial cells. Foxd1Cre;Tcf21f/f kidney showed an abnormal pattern of the renal vascular tree. The stroma of Foxd1Cre;Tcf21f/f kidney demonstrated marked reduction in β-catenin protein expression compared with wild type. Tcf21 was bound to β-catenin both upon β-catenin stabilization and at basal state as demonstrated by immunoprecipitation in vitro. In MK3/M15 metanephric mesenchymal cells, Tcf21 enhanced TCF/LEF promoter activity upon β-catenin stabilization, whereas DNA-binding deficient mutated Tcf21 did not enhance TCF/LEF promoter activity. Kidney explants of Foxd1Cre;Tcf21f/f showed low mRNA expression of stromal Wnt target genes. Treatment of the explants with CHIR, a Wnt ligand mimetic, restored Wnt target gene expression. Here, we also corroborated previous evidence that normal development of the kidney stroma is required for normal development of the Six2+ nephron progenitor cells, loop of Henle, and the collecting ducts.

Conclusions
These findings suggest that stromal Tcf21 facilitates medullary stroma development by enhancing Wnt/β-catenin signaling and promotes stromal cell proliferation and differentiation. Stromal Tcf21 is also required for the development of the adjacent nephron epithelia.
Tratamiento ortopédico funcional y mecánico para la corrección de la clase II esqueletal
Authors: Aguilar-Lucero Verónica-del-Carmen , Salame-Ortiz Verónica Alejandra 
Published: May 2022

Objetivo: Analizar las distintas alternativas de tratamiento basadas en Ortopedia Funcional y Mecánica, su efecto a nivel esqueletal, sus beneficios. Método: Revisión bibliográfica. Resultados: Se seleccionaron 15 artículos de un universo de 45, por cuanto eran los que tenían relación directa con el tema de investigación. Conclusión: Se ha logrado identificar las distintas alternativas de tratamiento con ortopedia funcional o mecánica que se pueden utilizar para el tratamiento de la Clase II esqueletal, corroboradas con resultados que evidencian Su efectividad tanto en los cambios craneofaciales, de tejidos blandos y dentales obtenidos al final de la terapéutica, los autores recomiendan la correcta evaluación de los pacientes, antes de determinar la aparatología a utilizar así cómo aprovechar los estadios tempranos de maduración y crecimiento para que los cambios en el patrón esqueletal sean más representativos, efectivos y alcancen el objetivo de mejorar la relación maxilo-mandibular.
Correlation Between Anemia And The Incidence Of Low Birth Weight (LBW)
Authors: Lolita Oktaviana Dewi , Titisari Ira , Antono Sumy Dwi 
Published: May 2022

Low Birth Weight (LBW) is newborn who weight less than 2,500 grams. LBW also has an impact on infant namely anemia, hypothermic, hyperbilirubinemia, hypoglyglyemi, respiratory syndrome. One major factor causes anemia during pregnancy. The update of this study is to discuss the relationship between anemia and LBW in developing countries, especially in the continents of Asia and Africa. The purpose of this study is to learn about anemia and LBW in developing countries on the Asian and African continents with literature review. The study design used is the study literature review by scoping study. A journal or article search involves using a keyword or keyword that "anemia to LBW, anemia in pregnancy, Low Birth Weight, LBW" and by using the designated inclusion and exclusion criteria. Assessments of the quality of articles or journals are made by using critical appraisal and will be carried out in 2021. Obtained 11 article publications from 2014 to 2020. From th review result showed that there is a correlation between anemia and low birth weight baby or LBW. The number of anemia in pregnancy does not always determine the number of babies born with LBW. Anemia in pregnancy can be the cause of the LBW baby.
Electronic publications in the coordinates of the ISBN system
Authors: Pogorelovska Iryna 
Published: May 2022

This article will examine the tendencies and the perspectives in e-publishing in the world as well as Ukraine, again the principles for assignment of ISBNs to electronic publications.
It is noted that e-book publishing demonstrates a high level of innovative development. Monitoring of domestic monographic electronic publications and the results of the analysis of the document flow of deposited publications received by the Book Chamber of Ukraine in accordance with current legislation show that publishers have difficulties in correctly interpreting certain provisions of current legal and regulatory documents. Often, publishers incorrectly assign ISBNs to electronic publications. Recommendations for the identification of monographic electronic publications in the ISBN system are given and examples are given as well.
The problems of the participants of the domestic book market regarding electronic publications are outlined. The importance of complying with the requirements of legal and regulatory documents on publishing. Electronic publication published in accordance with current national standards has a much higher chance of quickly finding its way to the target audience.
EMPLOYMENT OF THERMAL IMAGERS ІN WEAPON AІMІNG SYSTEMS
Authors: Zhіvetc Y. , Shumіgay O. , Yermolenko O. , Vetoshkіn O. 
Published: May 2022

Currently, іn varіous іndustrіes, much attentіon іs paіd to the development of thermal іmagіng equіpment. The mіlіtary іndustry solves a number of specіfіc tasks wіth іts help and constantly іncreases іts applіcatіon. But relevant and systematіc іnformatіon for a balanced solutіon of problems, especіally gіven the current tіme, іs not so much.
The current state of threats to Ukraіne's sovereіgnty and terrіtorіal іntegrіty, fіrst of all the ongoіng aggressіon of the Russіan Federatіon, requіres the іntroductіon of necessary ways to counter them, іmprovіng approaches to the formatіon of mіlіtary-technіcal polіcy, takіng іnto account the urgent need to update exіstіng weapons and mіlіtary (specіal) equіpment.
Mіlіtary usage are the most sіgnіfіcant area where thermal іmagers are used today. Nіght tіme has always been one of the obstacles to conducting combat actions.
Thermal іmagers are used by the armed forces as nіght vіsіon devіces to detect heat contrast targets at any tіme of the day, despіte the enemy's use of optіcal maskіng devіces іn the vіsіble range.
The thermal іmagіng method of control іs based on the fact that any processes occurrіng іn nature are accompanіed by the absorptіon and release of heat, changіng the іnternal energy of the body, whіch іn the state of thermodynamіc equіlіbrіum іs proportіonal to the temperature of the substance. As a result, the surfaces of physіcal bodіes acquіre a specіfіc temperature dіstrіbutіon.
The paper consіders the physіcal basіs, the prіncіple of operatіon of thermal іmagers, analyzes the maіn technіcal parameters that most affect both theіr performance and cost, as well as the maіn advantages and dіsadvantages of cooled and uncooled thermal іmagіng systems. Covered areas and optіons for the use of thermal іmagers, as well as problematіc іssues of theіr applіcatіon by unіts of the Armed Forces of Ukraіne revealed areas for further іmprovement of thermal іmagers.
Thermal іmagіng equіpment іs becomіng a necessary component of the complex of safety systems and іs currently actіvely used as a hіghly effectіve means of surveіllance. The effectіve use of a thermal іmager іs determіned by the ratіonalіty of choosіng a specіfіc model or modіfіcatіon dependіng on the requіred technіcal characterіstіcs.
The relevance of thіs work lіes іn the need to іntroduce fundamentally new concepts for the іntegratіon of thermal іmagіng equіpment.
WAYS OF DEVELOPMENT A COMPLEX OF AVIONICS FOR HELICOPTERS OF MI-8 TYPE OF THE AIR FORCES OF UKRAINIAN ARMED FORCES
Authors: Makarov S. , Kolomiiets V. , Mistsenko R. , Pokhodenko А. , Harnets D. 
Published: May 2022

Perspective directions of development of the onboard equipment complexes built on the principles of integrated modular avionics are considered. Features of architecture and interfaces of the complex, possibilities of unification and modernization of components of integrated modular avionics are analyzed, new functional possibilities, principles of reliability and safety failure of the complex are described, possibilities of realization of systems of electronic equipment on the basis of integrated modular avionics are considered. Possibilities of development of highly integrated onboard systems are analyzed.
The main conclusions and prospects for the use of research results. A necessary condition for further improvement of avionics equipment helicopter complexes of the Armed Forces of Ukraine is to conduct systematic pre- project military research and external design at the conceptual stage of formation of their technical accounting. These studies and preliminary design developments should include substantiation of the general concept (basic idea) of creation and combat application of the avionics equipment complex, which is planned for development, optimization of its performance characteristics values and design parameters that determine the technical accounting of the complex.
A UNIVERSAL TRANSFORMING PLATFORM FOR EVACUATING WOUNDED USING GROUND UNMANNED REMOTELY CONTROLLED COMPLEXES
Authors: Trofymenko S. , Herashchenko M. , Rudnichenko S. , Soboliev V. , Ilienko V. 
Published: May 2022

The paper describes the invention of a universal transforming platform for evacuating wounded using ground unmanned remotely controlled complexes and explains a method for evacuating the wounded.
A universal transforming platform for evacuating wounded using ground unmanned remotely controlled complexes contains a shield, which is a two-layer structure, the upper layer of which is made of foamed polymer, and the lower layer is made of aluminum alloy long cleats (hollow inside), two electromechanical devices for fastening (releasing) wire ropes, a platform transportation wire rope, platform fastening cables in a travelling position on a remote-controlled complex, victim fixation belts.
The method of hidden evacuation of the wounded consists in using a universal transforming platform that can be attached to all ground unmanned remotely controlled complexes. The victim who is not able to move independently from the forward edge of battle area is evacuated without exposing danger to personnel. This method allows to save the lives of both the wounded and medical personnel, who are still carrying out the evacuation of the wounded at the risk of their own lives.
Internalisasi Peran Guru PPKn Dalam Membentuk Karakter Peserta Didik (Studi Pada SMP Negeri 1 Bulagi Kecamatan Bulagi Kabupaten Banggai Kepulauan)
Authors: Ahmadin Ahmadin , Sabia Sirjon 
Published: May 2022

Tujuan penelitian ini mengetahui Internalisasi Peran Guru PPKn dalam Pembentukan Karakter Peserta Didik (Studi Pada SMP Negeri 1 Bulagi Kecamatan Bulagi Kabupaten Banggai Kepulauan). Metode penelitian yang dipakai ialah kualitatif dengan mengambil Jenis penelitian adalah Phenomenology. Data yang diperoleh kemudian dianalisis dengan langkah Pengumpulan data, Reduksi data, Penyajian data, Penarikan kesimpulan. Hasil Penelitian Menunjukan Internalisasi Peranan Guru PPKn merupakan pengaturan ide atau praktik-praktik Program perencanaan kepada peserta didik dalam memberikan pengajaran dan keteladanan tentang karakter dan budi pekerti berupa Membeina Ketakwaan, Membina sopan santun, Membina kedisiplinan, dan Membina kesehatan siswa dari orang lain menjadi bagian dari diri sendiri sebagai insan Kamil, dan Pembentukan Karakter Peserta didik merupakan suatu program Perencanaan Guru PPKn dalam menjalin hubungan yang baik dalam mengembangkan jati diri setiap peserta didik sebagai warga bangsa yang memiliki pengetahuan berdasarkan kebiasaan yang disiplin, berakhlak, takwa, dan berdaulat untuk mengikuti pengajaran yang efektif sehingga membentuk pribadi yang cerdas. Sehingga dapat disimpulkan bahwa Internalisasi Peran Guru PPKn dalam Pembentukan Karakter Peserta didik di SMP Negeri 1 Bulagi ialah suatu pembianaan ide atau praktik-praktik Program perencanaan kepada peserta didik dalam memberikan pengajaran dan keteladanan tentang karakter dan budi pekerti berupa Membeina disiplin, berakhlak, takwa berkepribadian dan berkeimanan, sebagai warga negara yang baik dan cerdas.
Meningkatkan Gerak Dasar Mendribble Dalam Permainan Bola Basket Melalui Metode Kooperatife Tipe STAD Siswa Kelas V SDN No. 68 Kota Timur Kota Gorontalo
Authors: Gani Jaria N. 
Published: May 2022

Masalah dalam penelitian ini adalah kurangnya penguasaan gerak dasar mendribble, kurangnya fasilitas seperti lapangan basket masih belum terdapat di sekolah serta penggunaan metode pembelajaran yang masih kurang efektif. Tujuan penelitian ini adalah untuk meningkatkan gerak dasar mendribble dalam permainan bola basket pada siswa kelas V di SDN No. 68 Kota Timur, Kota Gorontalo melalui metode kooperatif tipe STAD. Berdasarkan hasil penelitian tindakan kelas yang dilakukan oleh peneliti bahwa terjadi peningkatan rata-rata keterampilan mendribble bola yakni pada observasi awal rata-rata kemampuan siswa dalam mendribble bola mencapai 59,58. Setelah di adakan tindakan siklus satu terjadi peningkatan mencapai 9,59 menjadi 69,17. Namun pada nilai capaian dalam siklus satu ini belum memenuhi indikator kinerja. Pada tindakan siklus satu ini juga belum mencapai indikator kinerja. Maka dilanjutkan lagi dengan tindakan siklus dua dan peroleh hasil capaian 80,42 atau terjadi peningkatan sebesar 11,25. Dengan demikian rata-rata peningkatan dari observasi awal sampai siklus dua sebesar 20,84. Adanya peningkatan keterampilan mendribble bola dalam setiap siklusnya yakni rata-rata 25% dengan demikian hipotesis yang berbunyi terjadi peningkatan keterampilan mendribble bola dalam permainan bola basket melalui strategi kelompok pada kelas V SDN No. 68 Kota Timur dapat terbukti.
Permettre un ancrage par le soin psychique sur fond du péril du passage à l’acte
Authors: Holvoet Mathilde , Masson Antoine 
Published: May 2022

La question de la mesure du risque de passage à l’acte est un vaste débat dont la réponse n’est jamais binaire. La réflexion menée autour de cette question a pour visée d’approcher comment l’ancrage par le soin psychique amènerait à une évolution autre que meurtrière pour le sujet. Partir d’une situation clinique permet d’articuler les différents aspects d’une rencontre avec le soin. Nous aborderons ici quelles sont les possibilités de déplacements de la violence par le soin, c’est-à-dire par la « fonction de contention du cadre coercitif » et la « fonction de contenance du cadre soignant » (Morhain, 2012) 1 . Nous développerons également l’aspect de la crise homicidaire comme le pendant de la crise suicidaire, ce qui permettra de venir questionner ce que le sujet cherche à atteindre dans l’autre.
Lacan et le culturalisme. Chronique d’une résistance « inactuelle » à la psychanalyse
Authors: Guérin Nicolas 
Published: May 2022

Les thèses culturalistes en psychanalyse ont fini par s’imposer dans le paysage psychanalytique nord-américain malgré son apparente diversité. Concurremment il semble qu’outre-Atlantique les critiques de ces thèses se soient éteintes ou soient devenues plus ou moins inaudibles. Pourtant, avant même l’essor de ce courant, Freud avait très tôt identifié la dérive de telles thèses pour la psychanalyse. Lacan, quant à lui, craignait que des notions-clés de son enseignement soient détournées au profit du culturalisme dont il avait remarqué le succès grandissant. Aujourd’hui, en France, beaucoup de travaux de psychanalyse vérifient malheureusement les craintes de Lacan. Cet article, dont la version française est ici publiée dans la revue Essaim , a été soumis, discuté et accepté par le Journal of the American Psychoanalytic Association . On en tirera quelques conséquences.
Le cancer du sens
Authors: Sous Jean-Louis 
Published: May 2022

L’hypothèse d’un effet psychosomatique proposée par Jacques Lacan nous fait passer de la conversion signifiante qui maintient une liaison symbolique à une perforation corporelle qui précipite une lésion dans le corps. Un trop de sens fait trou dans le corps. Holophrase voire hiéroglyphes en marqueraient les cicatrices. Comment entendre le renvoi littéraire qu’il établit avec les paroles gelées de François Rabelais ?
Côté cœur, côté tête
Authors: Tremblay Sacha 
Published: May 2022

Avant l’affaire Emma Eckstein, les divers troubles médicaux de Sigmund Freud ont constitué le principal sujet de litige entre celui-ci et Wilhelm Flieβ, qui entendait en effet guérir son ami au moyen de son traitement des névroses réflexes nasales. La mise en relation de quelques textes prépsychanalytiques avec la correspondance des deux hommes montre non seulement que Freud s’est appuyé, pour théoriser la névrose d’angoisse, sur son propre « cas » de malade, mais que celle-ci avait pour fonction, revendiquant ses troubles de santé spécifiques, de le soustraire à la thérapeutique fliesséenne.
L’Espagne du début du XX e siècle : un cas pour repenser la bourgeoisie
Authors: Fernandez Alexandre 
Published: May 2022

Certaine analyse sur l’histoire sociale de l’Espagne, y compris chez certains contemporains ou auteurs postérieurs se réclamant du marxisme, répète que le pays a manqué de bourgeoisie, ou que les bourgeois n’y ont pas rempli leur « mission historique », que le pays n’aurait pas connu, en somme, à l’étape historique du développement du capitalisme, entre le dernier tiers du xix e siècle et 1931, de « révolution bourgeoise » classique qui eût rompu, vraiment, les structures d’ancien régime. Reprendre la réflexion en s’attachant aux conditions spécifiques d’accumulation et de reproduction du capital parmi les différents groupes de la classe dirigeante espagnole doit permettre de mieux cerner ce que fut le rôle de la bourgeoisie espagnole au premier tiers du vingtième siècle.
Le vicaire savoyard de Rousseau : idiot ou philosophe ?
Authors: Vargas Yves 
Published: May 2022

Le lecteur d’ Émile s’étonne que Rousseau ait introduit un « vicaire » dans le récit de l’histoire de la nature humaine. Le but de cette opération est d’établir la nécessité de l’existence de Dieu dans l’anthropologie sociale pour fonder la morale sur des bases naturelles. Mais les arguments du vicaire sont surprenants de faiblesse, alliant les contradictions, la pure rhétorique, les sophismes et l’ignorance affichée. Connaissant l’esprit de système de Rousseau, il faut établir la cohérence de cette incohérence. Le vicaire épouse tour à tour les époques contrastées de l’histoire humaine, leur myopie, leur naïveté, mais il les rectifie en gommant leurs erreurs et en instaurant le monothéisme au lieu de l’animisme spontané des premiers hommes. En cela, le vicaire, ni idiot ni philosophe, présente une religion naturelle raisonnée, fruit historique rétroactif des errements de l’histoire humaine.
Si le soin m’était conté
Authors: Millard Clotilde , Les Plumes Singulières  
Published: May 2022

La psychanalyse est une pratique créative car dépendante d’un sujet singulier. Elle s’invente à partir d’une rencontre entre au moins deux êtres. Ce texte, écrit à plusieurs, rend compte d’une praxis qui se construit en fonction des protagonistes en présence et témoigne que le soin psychique est un art qui demande tact et inventivité : un soin sur-mesure, loin du prêt à porter des manuels de bonnes pratiques.
Sociologie politique de l’action publique
Authors: Le Galès Patrick , Surel Yves 
Published: May 2022

Cette contribution montre combien l’article de Pierre Muller, « Les approches cognitives des politiques publiques » ( Revue française de science politique , 50 [2], avril 2000, p. 189-208), s’est avéré un papier de combat visant à établir l’analyse des politiques publiques comme un sous-champ essentiel de la science politique. Notre article reprend les questions majeures de l’ordre social et politique, d’une part, de l’autonomie des politiques publiques, d’autre part, qui sous-tendent la problématique de recherche articulée autour de la notion de référentiel. Il revient sur certaines dimensions de l’analyse, la différenciation avec d’autres théories concurrentes et élabore un bilan du référentiel qui, à la différence des questions posées par P. Muller, a perdu sa position centrale dans la sociologie politique de l’action publique. Il montre comment les enchevêtrements d’échelles et la multiplication des acteurs et des politiques ont rendu moins pertinentes la recherche d’un référentiel macro dans un cadre national, renforçant les approches en termes de discours, d’argumentation, d’idée plus situées et limitées. Mais avec la crise climatique, la question du « global » n’a pas dit son dernier mot.