bluuebunny/crossref_metadata_2025_split huggingface dataset:
The NSF Law and Social Sciences Program
Authors: Wasby Stephen L. 
Published: December 2022

The National Science Foundation provides support for basic social science research on law and legal institutions through the Law and Social Sciences Program. The primary emphasis of the program is on research that will enhance understanding of the nature and sources of variation in legal rules and institutions and their consequences. Proposals directed to developing methodologies for the social scientific study of law are also considered. Proposals concerning criminal aspects of the law will be considered if they relate primarily to theoretical questions in the social scientific study of the law. However, the central focus of the Law and Social Sciences Program is on noncriminal aspects of the legal system.Those who anticipate submitting proposals might keep in mind the broad concerns that are central to the program:1. The capacity of law, through statutes, administrative regulations, and court decisions, to affect individual and organizational behavior, its limitations in regulating action, conditions which enhance or diminish the impact of law, and the processes by which that impact is achieved or diminished.2. The use of alternative methods, both formal (legal) and informal (extra-legal), for dealing with disputes, and factors that contribute to the selection of the alternatives used.3. Change in the legal system, its causes and the processes by which it occurs, with particular emphasis on factors affecting the use of law as an instrument of social control.
Policy and Research: A Tough Combination
Authors: Shalala Donna E. 
Published: December 2022

I am deeply touched by your invitation to receive the Pi Sigma Alpha Award. To be added to a list that includes Ernest Giffith, Francis Wilcox and Scotty Campbell is, of course, a great honor.I assume that one of the reasons I have been singled out for this award is because I am on that short list of surviving political scientists in a city dominated at the highest levels by lawyers, economists and engineers.Recently, I read Bruce Adams' article in the November/December 1979 Public Administration Review titled, “The Limitations of Muddling Through: Does Anyone in Washington Really Think Anymore?” In the article, Adams suggests that the political decision-making process is characterized by individuals who are “running themselves ragged on a series of marginal, short-run issues and problems.”
Reforming the “President”: The Individual as Leader
Authors: Edwards George C. 
Published: December 2022

Proposals to reform the presidency fall into three increasingly exclusive categories. The most inclusive are those that focus on reforming the American political system and by doing so altering the balance of power within the government, usually in favor of the chief executive. The effort to strengthen the party system is probably the most prominent representative of this orientation. Other proposals, such as a presidential item veto, would increase the president's power on a more modest scale but still require change in the fundamental rules of the game.A second class of proposals has the narrower aim of reforming the presidency as an institution. Rather than emphasizing increased power for the president, these recommendations attempt to aid the chief executive in carrying out his responsibilities more judiciously. They often focus on providing the president more or better decision-making resources. Plans for reorganizing or otherwise improving the White House staff system or the Executive Office of the President or for insulating the president from parochial demands through a single six-year term are notable examples of suggestions for institutional reform.The variety of reformist proposals that is most common and most restricted in scope concentrates on improving the presidency by changing the characteristics of the individuals who occupy the Oval Office. Some would have us pay more attention to the character or personality of candidates for the office, while others stress the importance of choosing presidents who possess the proper skills for governing. To achieve these goals, proponents of change advocate reforms ranging from alterations in the processes by which we select presidents to candidate psychoanalysis.
A Controlled Experiment of Surface Albedo Modification to Reduce Ice Melt
Authors: Johnson D. , Manzara A. , Field L. A. , Chamberlin D. R. , Sholtz A. 
Published: December 2022

AbstractLoss of reflectivity in the Arctic and the wider cryosphere is known to increase global temperature rise through an ice‐albedo feedback loop, which has the potential to lead to loss of summertime ice cover in the Arctic Ocean, and to accelerate global warming. Despite the urgency of this situation, there are few options being developed to preserve and restore ice reflectivity. Localized surface albedo modification using reflective materials offers a potential pathway to restore Arctic ice. We conducted a controlled experiment to determine effects of surface albedo modification on ice melt and thermodynamic processes of a pond. We applied a coating of hollow glass microspheres (HGMs) to a test section, while leaving a control section unmodified. Laboratory measurements show that the loading of HGM materials used corresponds to a reflectivity of 30%. We measured ice and snow thickness, albedo, incoming and outgoing shortwave and longwave radiation, and ice, water, and ambient temperatures. A 1‐D thermodynamic model was developed to quantify the effect of albedo modification on the processes of heat transfer, energy absorption and ice melt. The albedo increased from 0.17 on a control section to 0.36 on a test section. During the 2‐week melt period, there was a 29% reduction in net radiative energy into the test section and a 33% reduction of ice melting rate measured by volume. This experiment using quantitative methods elucidates the mechanisms of ice preservation through surface albedo modification and demonstrates its effectiveness.
Ultra‐Low Frequency Waves in the Hermean Magnetosphere: On the Role of the Morphology of the Magnetic Field and the Foreshock
Authors: Kallio E. , Jarvinen R. , Massetti S. , Alberti T. , Milillo A. , Orsini S. , De Angelis E. , Laky G. , Slavin J. , Raines J. M. , Pulkkinen T. I. 
Published: December 2022

AbstractUltra‐low frequency (ULF) waves have been observed in the Mercury's magnetosphere by the Mariner 10 and MErcury Surface, Space ENvironment, GEochemistry and Ranging missions. The observed ∼2 s (∼0.6 Hz) period waves in the magnetic field are proposed to be generated by dynamic processes in the Mercury's magnetosphere. We investigate the Hermean ULF waves with a global hybrid model. We found evidence for ∼2‐s circularly polarized right‐handed waves in Mercury's magnetosphere at the closest approach of BepiColombo mission's first Mercury flyby in the model. The most intense wave power occurs on the dawn side closed magnetic field lines. These waves were found to be generated on the hemisphere which is magnetically directly connected to the interplanetary magnetic field on the dayside and to the foreshock region. It is therefore possible that the generation mechanism of these waves is associated with the precipitating ion flux or with the wave activity in the foreshock region.
Dusk‐Dawn Asymmetries in SuperDARN Convection Maps
Authors: Walach M.‐T. , Grocott A. , Thomas E. G. , Staples F. 
Published: December 2022

AbstractThe Super Dual Auroral Radar Network (SuperDARN) is a collection of radars built to study ionospheric convection. We use a 7‐year archive of SuperDARN convection maps, processed in 3 different ways, to build a statistical understanding of dusk‐dawn asymmetries in the convection patterns. We find that the data set processing alone can introduce a bias which manifests itself in dusk‐dawn asymmetries. We find that the solar wind clock angle affects the balance in the strength of the convection cells. We further find that the location of the positive potential foci is most likely observed at latitudes of 78° for long periods (>300 min) of southward interplanetary magnetic field (IMF), as opposed to 74° for short periods (<20 min) of steady IMF. For long steady dawnward IMF the median is also at 78°. For long steady periods of duskward IMF, the positive potential foci tends to be at lower latitudes than the negative potential and vice versa during dawnward IMF. For long periods of steady Northward IMF, the positive and negative cells can swap sides in the convection pattern. We find that they move from ∼0–9 MLT to 15 MLT or ∼15–23 MLT to 10 MLT, which reduces asymmetry in the average convection cell locations for Northward IMF. We also investigate the width of the region in which the convection returns to the dayside, the return flow width. Asymmetries in this are not obvious, until we select by solar wind conditions, when the return flow region is widest for the negative convection cell during Southward IMF.
Understanding Model‐Observation Discrepancies in Satellite Retrievals of Atmospheric Temperature Using GISS ModelE
Authors: Casas Madeline C. , Schmidt Gavin A. , Miller Ron. L. , Orbe Clara , Tsigaridis Kostas , Nazarenko Larissa S. , Bauer Susanne E. , Shindell Drew T. 
Published: December 2022

AbstractWe examine multiple factors in the representation of satellite‐retrieved atmospheric temperature diagnostics in historical simulations of climate change during the satellite era (specifically 1979–2021) using GISS ModelE contributions to the Coupled Model Intercomparison Project (Phase 6) (CMIP6). The tropospheric and stratospheric trends in these diagnostics are affected by greenhouse gases (notably carbon dioxide and ozone), coupling with the ocean, volcanic aerosols, solar activity and compositional and dynamic feedbacks. We explore the impacts of internal variability, changing forcing specifications, composition interactivity, the quality of the stratospheric circulation, vertical resolution, and possible impacts of the mis‐specification of volcanic aerosol optical depths. Overall temperature trends throughout the satellite period are well captured, but discrepancies at all levels exist and have multiple distinct causes. We find that stratospheric comparisons (using Stratospheric Sounding Unit (SSU) retrievals and successor instruments) are most affected by variations in the representation of ozone depletion and feedbacks, followed by the volcanic signals. Tropospheric skill (using the Microwave Sounding Unit (MSU) retrievals) is affected by the trends in ocean heat uptake and tropospheric aerosols, but also by the representation of stratospheric processes through the impact of the Brewer‐Dobson circulation on the height of the tropical tropopause. We demonstrate that no single factor is the dominant cause of the discrepancies and that almost all observations lie within the broad envelope of structural uncertainty.
Disentangling the roles of dopamine and noradrenaline in the exploration-exploitation tradeoff during human decision-making
Authors: Cremer Anna , Kalbe Felix , Müller Jana Christina , Wiedemann Klaus , Schwabe Lars 
Published: December 2022

AbstractBalancing the exploration of new options and the exploitation of known options is a fundamental challenge in decision-making, yet the mechanisms involved in this balance are not fully understood. Here, we aimed to elucidate the distinct roles of dopamine and noradrenaline in the exploration-exploitation tradeoff during human choice. To this end, we used a double-blind, placebo-controlled design in which participants received either a placebo, 400 mg of the D2/D3 receptor antagonist amisulpride, or 40 mg of the β-adrenergic receptor antagonist propranolol before they completed a virtual patch-foraging task probing exploration and exploitation. We systematically varied the rewards associated with choice options, the rate by which rewards decreased over time, and the opportunity costs it took to switch to the next option to disentangle the contributions of dopamine and noradrenaline to specific choice aspects. Our data show that amisulpride increased the sensitivity to all of these three critical choice features, whereas propranolol was associated with a reduced tendency to use value information. Our findings provide novel insights into the specific roles of dopamine and noradrenaline in the regulation of human choice behavior, suggesting a critical involvement of dopamine in directed exploration and a role of noradrenaline in more random exploration.
Silent gene clusters encode magnetic organelle biosynthesis in a non-magnetotactic phototrophic bacterium
Authors: Dziuba M V , Paulus A , Schramm L , Awal R P , Pósfai M , Monteil C L , Fouteau S , Uebe R , Schüler D 
Published: December 2022

Abstract
Horizontal gene transfer is a powerful source of innovations in prokaryotes that can affect almost any cellular system, including microbial organelles. The formation of magnetosomes, one of the most sophisticated microbial mineral-containing organelles synthesized by magnetotactic bacteria for magnetic navigation in the environment, was also shown to be a horizontally transferrable trait. However, the mechanisms determining the fate of such genes in new hosts are not well understood, since non-adaptive gene acquisitions are typically rapidly lost and become unavailable for observation. This likely explains why gene clusters encoding magnetosome biosynthesis have never been observed in non-magnetotactic bacteria. Here, we report the first discovery of a horizontally inherited dormant gene clusters encoding biosynthesis of magnetosomes in a non-magnetotactic phototrophic bacterium Rhodovastum atsumiense. We show that these clusters were inactivated through transcriptional silencing and antisense RNA regulation, but retain functionality, as several genes were able to complement the orthologous deletions in a remotely related magnetotactic bacterium. The laboratory transfer of foreign magnetosome genes to R. atsumiense was found to endow the strain with magnetosome biosynthesis, but strong negative selection led to rapid loss of this trait upon subcultivation, highlighting the trait instability in this organism. Our results provide insight into the horizontal dissemination of gene clusters encoding complex prokaryotic organelles and illuminate the potential mechanisms of their genomic preservation in a dormant state.
3D-FVS: construction and application of three-dimensional fundus vascular structure model based on single image features
Authors: Yao Zhaomin , Luo Renli , Xing Chencong , Li Fei , Zhu Gancheng , Wang Zhiguo , Zhang Guoxu 
Published: December 2022

Abstract
Background
Fundus microvasculature may be visually observed by ophthalmoscope and has been widely used in clinical practice. Due to the limitations of available equipment and technology, most studies only utilized the two-dimensional planar features of the fundus microvasculature.

Methods
This study proposed a novel method for establishing the three-dimensional fundus vascular structure model and generating hemodynamic characteristics based on a single image. Firstly, the fundus vascular are segmented through our proposed network framework. Then, the length and width of vascular segments and the relationship among the adjacent segments are collected to construct the three-dimensional vascular structure model. Finally, the hemodynamic model is generated based on the vascular structure model, and highly correlated hemodynamic features are selected to diagnose the ophthalmic diseases.

Results
In fundus vascular segmentation, the proposed network framework obtained 98.63% and 97.52% on Area Under Curve (AUC) and accuracy respectively. In diagnosis, the high correlation features extracted based on the proposed method achieved 95% on accuracy.

Conclusions
This study demonstrated that hemodynamic features filtered by relevance were essential for diagnosing retinal diseases. Additionally, the method proposed also outperformed the existing models on the levels of retina vessel segmentation. In conclusion, the proposed method may represent a novel way to diagnose retinal related diseases, which can analysis two-dimensional fundus pictures by extracting heterogeneous three-dimensional features.
Building cloud computing environments for genome analysis in Japan
Authors: Ogasawara Osamu 
Published: December 2022

AbstractThis review article describes the current status of data archiving and computational infrastructure in the field of genomic medicine, focusing primarily on the situation in Japan. I begin by introducing the status of supercomputer operations in Japan, where a high-performance computing infrastructure (HPCI) is operated to meet the diverse computational needs of science in general. Since this HPCI consists of supercomputers of various architectures located across the nation connected via a high-speed network, including supercomputers specialized in genome science, the status of its response to the explosive increase in genomic data, including the International Nucleotide Sequence Database Collaboration (INSDC) data archive, is explored. Separately, since it is clear that the use of commercial cloud computing environments needs to be promoted, both in light of the rapid increase in computing demands and to support international data sharing and international data analysis projects, I explain how the Japanese government has established a series of guidelines for the use of cloud computing based on its cybersecurity strategy and has begun to build a government cloud for government agencies. I will also carefully consider several other issues of user concern. Finally, I will show how Japan’s major cloud computing infrastructure is currently evolving toward a multicloud and hybrid cloud configuration.
Schooling substantially improves intelligence, but neither lessens nor widens the impacts of socioeconomics and genetics
Authors: Judd Nicholas , Sauce Bruno , Klingberg Torkel 
Published: December 2022

AbstractSchooling, socioeconomic status (SES), and genetics all impact intelligence. However, it is unclear to what extent their contributions are unique and if they interact. Here we used a multi-trait polygenic score for cognition (cogPGS) with a quasi-experimental regression discontinuity design to isolate how months of schooling relate to intelligence in 6567 children (aged 9–11). We found large, independent effects of schooling (β ~ 0.15), cogPGS (β ~ 0.10), and SES (β ~ 0.20) on working memory, crystallized (cIQ), and fluid intelligence (fIQ). Notably, two years of schooling had a larger effect on intelligence than the lifetime consequences, since birth, of SES or cogPGS-based inequalities. However, schooling showed no interaction with cogPGS or SES for the three intelligence domains tested. While schooling had strong main effects on intelligence, it did not lessen, nor widen the impact of these preexisting SES or genetic factors.
Understanding India’s low-carbon energy technology startup landscape
Authors: Krishna Harilal , Kashyap Yash , Dutt Dwarkeshwar , Sagar Ambuj D. , Malhotra Abhishek 
Published: December 2022

AbstractLow-carbon energy technology (LCET) startups could play a key role in accelerating India’s decarbonization. Yet, our understanding of the LCET startup landscape and what shapes it remains low. Here we provide an analysis of the Indian LCET startup landscape to fill this gap. Our descriptive analysis of quantitative data on investment and patenting activities of LCET startups from 2010 to 2020 and qualitative data from 25 semi-structured interviews shows a substantial increase in investment and patenting activity, particularly after 2017, driven in large part by market-creation measures undertaken by the Indian government. However, there are large differences between LCET startups in different sub-sectors and core value-creating activities. Our findings suggest that the level of technological capabilities moderates the relationship between market-creation measures and innovation outcomes—thus highlighting the need to complement market-creation policies with long-term measures to strengthen technological capabilities. Furthermore, we propose a research agenda to improve our understanding of LCET entrepreneurship in developing economies.
Mixing dynamics at river confluences governed by intermodal behaviour
Authors: Sukhodolov A. N. , Shumilova O. O. , Constantinescu G. S. , Lewis Q. W. , Rhoads B. L. 
Published: December 2022

AbstractThe extent to which flows mix at confluences is pivotal for determining spatial patterns of water quality and biodiversity. Because mixing processes are complex, predicting rates and characteristic scales of mixing is difficult. Here we introduce a theory for confluence mixing dynamics of shallow flows in which the mixing process is controlled by the switching between two modes of behaviour—one similar to a wake behind an obstacle and the other similar to a mixing layer between two parallel flows. Dye visualizations of mixing in field-based controlled experiments agree with theoretical predictions and support transitional behaviour between the two mixing modes. According to our theoretical framework, the mixing interface can grow rapidly in wake mode, when large vortices are shed from a zone of stagnant flow within the confluence, but lateral shear between incoming flows is negligible. This rapid growth occurs even though flow curvature and shallowness inhibit growth through advective and turbulent lateral exchange of momentum and through bed friction. Our findings provide insight into the importance of different modalities of flow structure in controlling mixing at river confluences, thereby contributing to practical knowledge on the role of confluences in dispersal of contaminants in river systems.
Uniform thin ice on ultraflat graphene for high-resolution cryo-EM
Authors: Zheng Liming , Liu Nan , Gao Xiaoyin , Zhu Wenqing , Liu Kun , Wu Cang , Yan Rui , Zhang Jincan , Gao Xin , Yao Yating , Deng Bing , Xu Jie , Lu Ye , Liu Zhongmin , Li Mengsen , Wei Xiaoding , Wang Hong-Wei , Peng Hailin 
Published: December 2022

AbstractCryo-electron microscopy (cryo-EM) visualizes the atomic structure of macromolecules that are embedded in vitrified thin ice at their close-to-native state. However, the homogeneity of ice thickness, a key factor to ensure high image quality, is poorly controlled during specimen preparation and has become one of the main challenges for high-resolution cryo-EM. Here we found that the uniformity of thin ice relies on the surface flatness of the supporting film, and developed a method to use ultraflat graphene (UFG) as the support for cryo-EM specimen preparation to achieve better control of vitreous ice thickness. We show that the uniform thin ice on UFG improves the image quality of vitrified specimens. Using such a method we successfully determined the three-dimensional structures of hemoglobin (64 kDa), α-fetoprotein (67 kDa) with no symmetry, and streptavidin (52 kDa) at a resolution of 3.5 Å, 2.6 Å and 2.2 Å, respectively. Furthermore, our results demonstrate the potential of UFG for the fields of cryo-electron tomography and structure-based drug discovery.