bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maternal Age, Early Childhood Temperament, and Youth Outcomes
Authors: Yu Wei-hsin , Yan Hope Xu 
Published: October 2022

Abstract
Demographers and family researchers have long debated whether early childbearing has negative consequences on the offspring, but few have considered that the benefits of delayed childbearing (or the lack thereof) may not be universal. Using sibling data from the National Longitudinal Survey of Youth 1979 Children and Young Adults, we investigate how the relevance of mothers' age at childbirth to youth outcomes (academic performance, years of education completed, and psychological distress) may differ for youth whose early-childhood behavioral disposition (i.e., temperament) indicated varying degrees of insecure attachment. Results from family fixed-effects models, which take into account much of the unobserved heterogeneity among families, show that having an older mother is associated with improved educational and psychological outcomes for youth with a rather insecure early temperament. In contrast, mothers' age at childbirth hardly matters for children with a secure disposition. Further analysis indicates that the moderating effect of maternal age cannot be explained by the mother's first-birth timing, education, work status, income, or family stability. Older mothers' higher likelihood of prior child-rearing experience explains part of the older-mother advantage for temperamentally insecure children. However, the aging process, which equips older mothers with enhanced maturity, more calmness, and therefore greater capacity to overcome adversities, seems to account for the smaller detrimental effects of an insecure disposition on their children.
Gender, digital financial services and vulnerability in the era of pandemics: A cross-sectional analysis
Authors: Amidu Mohammed , Akakpo Agnes Akpene , Mensah James Kwame , Asiedu Edward 
Published: October 2022

Background: The COVID-19 pandemic has rapidly spread across the world, infecting millions and causing economic disruption on an unprecedented scale. While everyone is affected by the COVID-19 pandemic, vulnerable communities are at the greatest risk. The objective of this study is to examine the relationship between digital financial services (DFS), gender, and the vulnerability of informal settlement dwellers to COVID-19. Methods: We sampled a total of 2,697 households from 101 informal settlements across eleven out of sixteen administrative regions of Ghana. The regions were selected based on the relative severity of the pandemic, and the associated national lockdown regulations. Results: Adopting the multiple regression analytical technique, the results reveal three main findings: First, we observe that males in informal settlements are more likely to be exposed to infected people or a person who died from COVID-19 than females. However, women are more likely to be vulnerable to the pandemic than men as vulnerable populations have a higher susceptibility to pandemics due to less capacity to implement preparedness and response strategies due to disparities in their societal status. Finally, we find that the vulnerability of informal dwellers is moderated by the use of digital financial services. Conclusions: Our results provide policy implications for authorities designing policies to address vulnerability to pandemics in poor informal settlements in Africa.
Efficacy of a light convex appliance and mouldable ring in an early postoperative stoma with effluent leakage
Authors: del Teso Alberto Lado , del Pino Carmen , Jiménez Isabel , Lázaro Mireia , del Mar Medina María , Blázquez Eduardo García 
Published: October 2022

Aim: This study aimed to analyse the impact of using both a light convex appliance and mouldable ring in the early postoperative period on leakage frequency, peristomal skin health and quality of life after discharge. Methods: This prospective non-randomised study was performed in patients with a digestive stoma experiencing effluent leakage during the early postoperative period. Evaluation was performed at baseline (V1) during admission and at 2–3 weeks after discharge (V2). The outcomes measurements were: number of leaks per day; satisfaction (0 to 10 VAS scale); DET score evaluating discolouration (D); erosion/ulceration (E) and tissue overgrowth (T); stoma morphology and NANDA International nursing diagnosis, which measures anxiety, fear and image deterioration as well as insomnia. NANDA International diagnosis were evaluated as a percentage of cases with the diagnosis and categorically according to several dimension scores. Signed rank, McNemar, chi-squared and Bowker's tests were used for comparison. Results: Of 257 patients screened, 244 completed the study. The mean number of leak episodes using the light convex appliance and mouldable ring in the early postoperative period decreased from 3.4±5.2 (V1) to 1.3±2.3 (V2) (p<0.0001). Mean discolouration, erosion and tissue overgrowth (DET) score decreased from 3.3±3.3 (V1) to 1.6±2.3 (V2) (p<0.0001). Mean self-reported satisfaction with the appliance increased from 5.1±2 (V1) to 7.2±1.7 (V2) (p<0.0001). The proportion of patients with a retracted peristomal area changed from 27.9% to 21.7%, while that of patients with protruded stoma increased from 32.9% to 40% (p=0.025). Regarding NANDA International diagnosis, anxiety reduced from 36.5% to 9.5% (p<0.0001), fear from 40.6% to 4.9% (p<0.0001), image deterioration from 19.2% to 10.9% (p=0.002) and insomnia from 39.3% to 2.5% (p<0.0001). All the categorical dimensions evaluated for each NANDA International diagnosis improved (p<0.0001). Conclusion: Patients with an ostomy and effluent leakage in the early postoperative period clearly benefited from the use of both a light convex appliance and mouldable ring. This approach had a positive impact on number of leakages per day, peristomal skin status and patient satisfaction, as well as meeting several NANDA International nursing diagnosis criteria.
Monolithically integrated high-resolution full-color GaN-on-Si micro-LED microdisplay
Authors: Qi Longheng , Zhang Xu , Chong Wing Cheung , Lau Kei May 
Published: October 2022

Full-color micro-LED displays are being widely developed and regarded as a primary option in current microdisplay technologies to fulfill the urgent demands of metaverse applications in the next decade. In this paper, a monolithic full-color micro-LED microdisplay with a resolution of 423 pixels per inch is demonstrated through the integration of a blue GaN-on-Si display module and a quantum dots photoresist (QDs-PR) color conversion module. The

400
×
240

active-matrix blue micro-LED display with a dominant wavelength of 440 nm was monolithically fabricated using GaN-on-Si epiwafers and flip-chip bonded on a custom-designed complementary metal-oxide semiconductor backplane. A color conversion module was independently fabricated on a 4-in. sapphire substrate by applying red and green QDs-PR arrays and a color filter array through the standard lithography process. Combining the blue GaN-on-Si micro-LED display module and the lithography-based QDs-PR color conversion module, a full-color micro-LED display was achieved with a wide color gamut up to 104% of the standard red, green, and blue and a maximum brightness of over 500 nits. The influence of blue light leakage resulting from the possible misalignment of flip-chip bonding and crosstalk in the bottom GaN-on-Si display was investigated in which the percentages of efficient pumping light for the blue, green, and red subpixels are around 95%, 89%, and 92%, respectively. This prototype demonstrates potential scalability and low-cost volume production of high-resolution full-color micro-LED microdisplays soon.
Virtually-delivered Sudarshan Kriya Yoga (SKY) for Canadian veterans with PTSD: A study protocol for a nation-wide effectiveness and implementation evaluation
Authors: Ryk Justin , Simpson Robert , Hosseiny Fardous , Notarianni MaryAnn , Provencher Martin D. , Rudnick Abraham , Upshur Ross , Sud Abhimanyu 
Published: October 2022

Background
Post-traumatic stress disorder (PTSD) remains a significant treatment challenge among Canadian veterans. Currently accessible pharmacological and non-pharmacological interventions for PTSD often do not lead to resolution of PTSD as a categorical diagnosis and have significant non-response rates. Sudarshan Kriya Yoga (SKY), a complementary and integrative health (CIH) intervention, can improve symptoms of PTSD. In response to the COVID-19 pandemic, this intervention has pivoted to virtual delivery and may be reaching new sets of participants who face multiple barriers to care.

Objective
To evaluate the implementation and effectiveness of virtually delivered Sudarshan Kriya Yoga (SKY) on decreasing PTSD symptom severity, symptoms of depression, anxiety, and pain, and improving quality of life in Canadian veterans affected by PTSD.

Methods and analysis
Using a mixed-methods approach guided by the RE-AIM framework, we will conduct a hybrid type II effectiveness and implementation study of virtually delivered Sudarshan Kriya Yoga (SKY) for Canadian veterans. Effectiveness will be evaluated by comparing virtually delivered SKY to a waitlist control in a single-blinded (investigator and data analyst) randomized controlled trial (RCT). Change in PTSD symptoms (PCL-5) is the primary outcome and quality of life (SF-36), symptoms of depression (PHQ-9), anxiety (GAD-7), and pain (BPI) are secondary outcomes. The SKY intervention will be conducted over a 6-week period with assessments at baseline, 6-weeks, 12-weeks, and 30 weeks. The reach, effectiveness, adoption, implementation, and maintenance of the intervention will be evaluated through one-on-one semi-structured interviews with RCT participants, SKY instructors, health professionals, and administrators that work with veterans.

Discussion
This is the first investigation of the virtual delivery of SKY for PTSD in veterans and aims to determine if the intervention is effective and implementable at scale.
Association between coronary artery calcium and all-cause mortality: A large single-center retrospective cohort study
Authors: Wang Mu-Cyun , Lin Che-Chen , Chiang Hsiu-Yin , Chen Hung-Lin , Tsai Hsiu-Chen , Lin Wen-Yuan , Ho Hung-Chi , Kuo Chin-Chi 
Published: October 2022

Objective
Previous studies have revealed that coronary artery calcium is related to cardiovascular diseases and mortality. However, most studies have been conducted in Western countries and have excluded patients with pre-existing heart disease. We investigated the association between coronary artery calcium (CAC) and all-cause mortality in an Asian cohort and in subgroups stratified by age, sex, smoking, obesity, diabetes, cardiovascular disease, blood pressure, and biochemical parameters.

Methods
We conducted a retrospective cohort study on 4529 health examinees who underwent multidetector computed tomography in a tertiary medical center in Taiwan between 2011 and 2016. The mean follow-up was 3.5 years. Cox regression was used to estimate the relative hazards of death. Stratified analyses were performed.

Results
The all-cause mortality rates were 2.94, 4.88, 17.6, and 33.1 per 1000 person-years for CAC scores of 0, 1–100, 101–400, and >400, respectively. The multivariable adjusted hazard ratios (95% confidence intervals [CIs]) for all-cause mortality were 0.95 (0.53, 1.72), 1.87 (0.89, 3.90), and 3.05 (1.46, 6.39) for CAC scores of 1–100, 101–400, and >400, respectively, relative to a CAC score of 0. Compared with CAC ≤ 400, the HRs (95% CIs) for CAC > 400 were 6.46 (2.44, 17.15) and 1.94 (1.00, 3.76) in younger and older adults, respectively, indicating that age was a moderating variable (p = 0.02).

Conclusion
High CAC scores were associated with increased all-cause mortality. Although older adult patients had higher risks of death, the relative risk of death for patients with CAC > 400 was more prominent in people younger than 65 years.
The Origins of the Film Star System: Persona, Publicity and Economics in Early Cinema, Andrew Shail (2019)
Authors: Sprouse Miranda 
Published: October 2022

Review of: The Origins of the Film Star System: Persona, Publicity and Economics in Early Cinema, Andrew Shail (2019)
London: Bloomsbury Academic, 424 pp., ISBN: 9781788312073 (hbk), $120.00, ISBN: 9781350111417 (pdf), $108.00, ISBN: 9781350111424 (ebk), $108.00
Can Right Ventricular Branch Bypass Alleviate Right Ventricular Dysfunction?
Authors: Ali Sahin Mehmet , Yokuşoğlu Mehmet , Kuralay Erkan , Ozal Ertugrul 
Published: October 2022

Background
Right ventricle (RV) dysfunction after a coronary artery bypass grafting procedure is a challenge that adversely affects RV filling pressure and contraction. This study sought to determine whether additional bypass of an RV branch would lessen RV dysfunction.

Methods
Patients with severe right coronary artery (RCA) stenosis were divided into 2 groups. Group 1 patients (n = 50) had a single distal bypass on the RCA. Group 2 patients (n = 50) had both distal RCA and additional bypass on the RV branch of the RCA. Right ventricular function was examined by echocardiogram by measuring transannular plane systolic excursion, fractional area change, tissue Doppler S-wave velocity, and inferior vena cava diameter.

Results
Transannular plane systolic excursion and fractional area change measurements rapidly decreased below the cutoff in both groups, but group 2 patient values reached normal limits at 90 days. Tissue Doppler S-wave velocity reached the normal limit in 7 days. Inotropic agents were required in 11 patients in group 1 and 2 patients in group 2 (P = .013). The mean (SD) intensive care unit stay was 2.11 (1.12) days and 1.45 (0.71) days (P = .033), and the hospital stay was 7.32 (1.44) days and 6.22 (0.45) days in groups 1 and 2, respectively (P = .027).

Conclusion
The data in this study suggest that an additional graft on the RV branch of the RCA (eg, conus, marginal, any good runoff vessels on the RV) prevents severe RV dysfunction and allows for rapid recovery of RV dysfunction after off-pump coronary surgery.
Nonstationary Poiseuille flow of a non-Newtonian fluid with the shear rate-dependent viscosity
Authors: Panasenko Grigory , Pileckas Konstantin 
Published: October 2022

Abstract
A nonstationary Poiseuille flow of a non-Newtonian fluid with the shear rate dependent viscosity is considered. This problem is nonlinear and nonlocal in time and inverse to the nonlinear heat equation. The provided mathematical analysis includes the proof of the existence, uniqueness, regularity, and stability of the velocity and the pressure slope for a given flux carrier and of the exponential decay of the solution as the time variable goes to infinity for the exponentially decaying flux.
Report from the HarmoSter study: inter-laboratory comparison of LC-MS/MS measurements of corticosterone, 11-deoxycortisol and cortisone
Authors: Fanelli Flaminia , Bruce Stephen , Cantù Marco , Temchenko Anastasia , Mezzullo Marco , Lindner Johanna M. , Peitzsch Mirko , Binz Pierre-Alain , Ackermans Mariette T. , Heijboer Annemieke C. , Van den Ouweland Jody , Koeppl Daniel , Nardi Elena , Rauh Manfred , Vogeser Michael , Eisenhofer Graeme , Pagotto Uberto 
Published: October 2022

Abstract

Objectives
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) panels that include glucocorticoid-related steroids are increasingly used to characterize and diagnose adrenal cortical diseases. Limited information is currently available about reproducibility of these measurements among laboratories. The aim of the study was to compare LC-MS/MS measurements of corticosterone, 11-deoxycortisol and cortisone at eight European centers and assess the performance after unification of calibration.

Methods
Seventy-eight patient samples and commercial calibrators were measured twice by laboratory-specific procedures. Results were obtained according to in-house and external calibration. We evaluated intra-laboratory and inter-laboratory imprecision, regression and agreement against performance specifications derived from 11-deoxycortisol biological variation.

Results
Intra-laboratory CVs ranged between 3.3 and 7.7%, 3.3 and 11.8% and 2.7 and 12.8% for corticosterone, 11-deoxycortisol and cortisone, with 1, 4 and 3 laboratories often exceeding the maximum allowable imprecision (MAI), respectively. Median inter-laboratory CVs were 10.0, 10.7 and 6.2%, with 38.5, 50.7 and 2.6% cases exceeding the MAI for corticosterone, 11-deoxycortisol and cortisone, respectively. Median laboratory bias vs. all laboratory-medians ranged from −5.6 to 12.3% for corticosterone, −14.6 to 12.4% for 11-deoxycortisol and −4.0 to 6.5% for cortisone, with few cases exceeding the total allowable error. Modest deviations were found in regression equations among most laboratories. External calibration did not improve 11-deoxycortisol and worsened corticosterone and cortisone inter-laboratory comparability.

Conclusions
Method imprecision was variable. Inter-laboratory performance was reasonably good. However, cases with imprecision and total error above the acceptable limits were apparent for corticosterone and 11-deoxycortisol. Variability did not depend on calibration but apparently on imprecision, accuracy and specificity of individual methods. Tools for improving selectivity and accuracy are required to improve harmonization.
Saliva – a new opportunity for fluid biopsy
Authors: Huang Zhijie , Yang Xiaoxia , Huang Yisheng , Tang Zhengming , Chen Yuanxin , Liu Hongyu , Huang Mingshu , Qing Ling , Li Li , Wang Qin , Jie Zhuye , Jin Xin , Jia Bo 
Published: October 2022

Abstract
Saliva is a complex biological fluid with a variety of biomolecules, such as DNA, RNA, proteins, metabolites and microbiota, which can be used for the screening and diagnosis of many diseases. In addition, saliva has the characteristics of simple collection, non-invasive and convenient storage, which gives it the potential to replace blood as a new main body of fluid biopsy, and it is an excellent biological diagnostic fluid. This review integrates recent studies and summarizes the research contents of salivaomics and the research progress of saliva in early diagnosis of oral and systemic diseases. This review aims to explore the value and prospect of saliva diagnosis in clinical application.
A SIMEX approach for meta-analysis of diagnostic accuracy studies with attention to ROC curves
Authors: Guolo Annamaria , Pesantez Cabrera Tania Erika 
Published: October 2022

Abstract
Bivariate random-effects models represent an established approach for meta-analysis of accuracy measures of a diagnostic test, which are typically given by sensitivity and specificity. A recent formulation of the classical model describes the test accuracy in terms of study-specific Receiver Operating Characteristics curves. In this way, the resulting summary curve can be thought of as an average of the study-specific Receiver Operating Characteristics curves. Within this framework, the paper shows that the standard likelihood approach for inference is prone to several issues. Small sample size can give rise to unreliable conclusions and convergence problems deeply affect the analysis. The proposed alternative is a simulation-extrapolation method, called SIMEX, developed within the measurement error literature. It suits the meta-analysis framework, as the accuracy measures provided by the studies are estimates rather than true values, and thus are prone to error. The methods are compared in a series of simulation studies, covering different scenarios of interest, including deviations from normality assumptions. SIMEX reveals a satisfactory strategy, providing more accurate inferential results if compared to the likelihood approach, while avoiding convergence failure. The approaches are applied to a meta-analysis of the accuracy of the ultrasound exam for diagnosing abdominal tuberculosis in HIV-positive subjects.
Identifying HIV sequences that escape antibody neutralization using random forests and collaborative targeted learning
Authors: Jin Yutong , Benkeser David 
Published: October 2022

Abstract
Recent studies have indicated that it is possible to protect individuals from HIV infection using passive infusion of monoclonal antibodies. However, in order for monoclonal antibodies to confer robust protection, the antibodies must be capable of neutralizing many possible strains of the virus. This is particularly challenging in the context of a highly diverse pathogen like HIV. It is therefore of great interest to leverage existing observational data sources to discover antibodies that are able to neutralize HIV viruses via residues where existing antibodies show modest protection. Such information feeds directly into the clinical trial pipeline for monoclonal antibody therapies by providing information on (i) whether and to what extent combinations of antibodies can generate superior protection and (ii) strategies for analyzing past clinical trials to identify in vivo evidence of antibody resistance. These observational data include genetic features of many diverse HIV genetic sequences, as well as in vitro measures of antibody resistance. The statistical learning problem we are interested in is developing statistical methodology that can be used to analyze these data to identify important genetic features that are significantly associated with antibody resistance. This is a challenging problem owing to the high-dimensional and strongly correlated nature of the genetic sequence data. To overcome these challenges, we propose an outcome-adaptive, collaborative targeted minimum loss-based estimation approach using random forests. We demonstrate via simulation that the approach enjoys important statistical benefits over existing approaches in terms of bias, mean squared error, and type I error. We apply the approach to the Compile, Analyze, and Tally Nab Panels database to identify AA positions that are potentially causally related to resistance to neutralization by several different antibodies.
A systematic literature review on channel estimation in MIMO-OFDM system: performance analysis and future direction
Authors: Manasa B.M.R. , Venugopal P.  
Published: October 2022

Abstract
Multiple Input Multiple Output-Orthogonal Frequency Division Multiplexing (MIMO-OFDM) is a familiar modern wireless broadband technology due to its resistance against multipath fading, high data transmission rate, and spectral efficiency. This technology delivers dependable communication as well as a large range of coverage. The precise recovery of Channel State Information (CSI) and synchronization among the receiver and transmitter are two major challenges for MIMO-OFDM systems. Several estimate procedures, like blind, pilot-aided, and semi-blind channel estimating, are used to recover channel state information. Yet, those systems have several flaws that cause them to perform poorly. Hence, this paper describes the basic introduction of the Channel Estimation (CE) process in the MIMO-OFDM system. The main goal of this survey is to study analyzing and categorizing the channel estimation algorithms, and simulation tools in different contributions. Further, the performance analysis with different performance metrics from diverse contributions is pointed out. Thus, this review article presents a detailed overview of the various channel estimation schemes that have been exploited in the OFDM channel to enhance the estimation of the CSI in the MIMO-OFDM systems. This work presents and discusses the relevant comparative results and computational complexity for all of these CE systems. Furthermore, there is a list of open study directions for further exploration.