bluuebunny/crossref_metadata_2025_split huggingface dataset:
The future of long‐term monitoring after catheter and surgical ablation for atrial fibrillation
Authors: Baman Jayson R. , Passman Rod S. 
Published: January 2022

AbstractIn recent years, there has been an emergence of long‐term cardiac monitoring devices, particularly as they relate to nonprescribed, user‐initiated, wearable‐ and/or, smartphone‐based devices. With these new available data, practitioners are challenged to interpret these data in the context of routine clinical decision‐making. While there are many potential uses for long‐term rhythm monitoring, in this review, we will focus on the evolving role of this technology in atrial fibrillation (AF) monitoring after catheter and/or surgical ablation. Here, we explore the landscape of prescription‐based tools for long‐term rhythm monitoring; investigate commercially available technologies that are accessible directly to patients, and look towards the future with investigative technologies that could have a growing role in this space.
Protecting the Rhine‐Meuse delta against sea level rise: What to do with the river's discharge?
Authors: De Bruijn Karin M. , Diermanse Ferdinand L. M. , Weiler Otto M. , De Jong Jurjen S. , Haasnoot Marjolijn 
Published: January 2022

AbstractSea level rise (SLR) will affect water levels and increase flood risk in river deltas. To adapt river deltas to SLR, various strategies can be followed. Many urbanised river deltas already have flood protection in place. Continuing a protection strategy under an increasing SLR, would mean higher embankments along the coast and rivers and possibly closing off the river mouths from the sea. However, closing of rivers will hamper the river flow. How to adapt river deltas and enabling rivers to discharge into the sea is a challenging question. This paper assesses impacts of SLR on flood risks in the Rhine‐Meuse Delta in the Netherlands in case the current protection strategy is continued and explores two alternative protection strategies: (1) a closed system with pumps and discharge sluices and (2) an open system in which rivers are diverted to less densely populated areas. The second alternative results in a more flexible river delta, which can accommodate larger SLR. The paper shows that a systems approach and using quantitative assessments of the implications of strategies is possible. This is needed to further assess the adaptation options, so we can anticipate and adapt when needed and avoid regret of decisions.
Dreams of time and space: exploring digital literacies through playful transmedia storying in school
Authors: Colvert Angela 
Published: January 2022

AbstractTo support digital literacies in schools, fundamental reorientation and rethinking is required to develop ‘appropriate’ pedagogical practices which are aligned with (and extend) the current curriculum. To achieve this, new flexible frameworks and tools are needed to support educators to work creatively and productively within the current constraints and challenge dominant discourses. Addressing this necessity, I present the findings from a 2‐year research project, funded by the British Academy, entitled Playful Pedagogies: Developing New Literacies in the Classroom through the Design and Play of Alternate Reality Games which set out to investigate how engaging teachers in the co‐design of an alternate reality game might develop their understanding of digital literacies (their own and those of the children in their classes). The game, ‘Join the DOTS (Dreams of Time and Space)’, provides a fictional context and pedagogical framework for exploring the potential of ‘transmedia storying’ in schools. The associated planning tool and observation frame support teachers to reflect on the skills, critical questions and cultural connections shaped during play and foreground the value of noticing literacy processes as they emerge ‘in the moment’. These have significant implications educators and policy makers and those developing transmedia narratives with and for young people.
Weaving critical hope: story making with artists and children through troubled times
Authors: Stephenson Lisa , Daniel Alastair , Storey Vicky 
Published: January 2022

AbstractRe‐imagining Home was a collective immersive story response for children ages 7–12 years during Covid curated by artists from The Story Makers Company. This experience focused on connecting children in new ways through the processes of drama and storying. This paper explores the nuanced responses that children and artists negotiated online/offline story spaces as they lived through these experiences. ARTography (Irwin, 2013) is used as a form of practitioner inquiry from three of the eight artists perspectives, to critically examine the tensions of embedding our affective offline practices online. This includes exploring the rhizomatic ways in which children engaged both online/offline through the artefacts that they shared. The ways in which these hybrid story spaces reflected our affective experiences are explored as the ‘richness of the meanwhile’ (Bogost in Facer 2019, p. 7), described as ‘the dense network of activity going on at any one time’. These shared ‘fragmentary’ stories are explored as a critical pedagogy of hope, considering how the Story Weave offered new possibilities for reimagining future educator practices in troubled times.
Lethal COG6‐CDG in neonatal patient with arachnodactyly, joint contractures, and skin manifestations: Founder mutation in the Southeastern European population?
Authors: Ververi Athina , Stathopoulou Theodora , Kontou Aggeliki , Farini Maria , Vlahou Georgia , Demiris Nikolaos , Sarafidis Kosmas 
Published: January 2022

AbstractHerein, we report a lethal case of the ultra‐rare COG6‐congenital disorder of glycosylation (CDG) presenting with skin manifestations (scaling and erosions) and joint contractures in a neonate of Albanian origin. The patient was homozygous for a COG6 pathogenic variant, previously reported in another three individuals of Greek, Bulgarian and Turkish descent. The presence of a founder mutation in the geographical area is possible. The index case emphasizes the need to consider CDGs in neonatal patients with skin manifestations and joint contractures, particularly patients of Southeastern European or West Asian origin.
Estrogens in wastewaters: Can different operating conditions improve their removal in anaerobic conditions?
Authors: Louros Vitória L. , Sousa Andreia F. C. , Lima Diana L. D. , Santos Pedro M. P. , Leitão Jorge H. , Esteves Valdemar I. , Nadais Helena G. A. 
Published: January 2022

AbstractThe removal of estrone (E1) and 17α‐ethinylestradiol (EE2) from synthetic wastewater under anaerobic conditions, at environmental relevant concentrations (80 and 4 μg L−1, for E1 and EE2, respectively), was here assessed. Results indicated that the increase in temperature favoured E1 removal (complete removal at 25°C, and 34°C after 25 h), while EE2 does not seem to be affected. The lowest mixed liquor suspended solid (MLSS) concentrations promoted a higher removal of E1 and EE2 (with a complete removal for E1 after 25 h and of 74% after 265 h for EE2 with a MLSS of 2 g L−1). Moreover, the presence of nitrate does not seem to have influence on E1 and EE2 removal. These studies represent a step forward in the knowledge of the influence of different conditions on the estrogens' removal under anaerobic conditions.
Cenozoic magmatism and plate tectonics in western North America: Have we got it wrong?
Authors: Glazner* Allen F. 
Published: January 2022

ABSTRACT
The current tectonic framework for understanding Cenozoic magmatism in western North America was laid out in a series of influential papers in the early days of the plate-tectonics revolution. These ideas, largely developed through deductive analysis, were so revolutionary yet seemingly self-evident that they quickly passed from hypothesis to axiom. These include the following. (1) Inboard and outboard sweeps of magmatism resulted from shallowing and then rapid steepening of a subducted slab. (2) The Oligocene–Miocene ignimbrite flareup resulted from sinking and rollback of a shallow slab. (3) Late Cenozoic basaltic magmatism resulted from opening of a slab window. (4) The current Cascade arc is the remnant of a much more continuous ancestral arc that ran the length of western North America. When tested against current databases of igneous rock ages and chemical analyses, these conjectures largely fail; some are clearly contradicted, whereas others are possible but ad hoc and unfalsifiable. Ironically, the plate-tectonics revolution nicely explains plate-boundary magmatism in much of the world but is less successful in western North America, where many of these links were first developed. It is time for a second revolution.
How spin down and radioactive decay drive rocky planet evolution
Authors: Criss* Robert E. , Hofmeister Anne M. 
Published: January 2022

ABSTRACT
Most differences in the gross surface morphologies, tectonic styles, overall geologic histories, and atmospheres of the rocky bodies in the solar system can be explained by contributions and dissipation of gravitational and radiogenic energy over geologic time. These two energy sources are large and measurable and can be extrapolated back in time. Accretion was likely cold, and directly converted gravitational potential energy into axial spin, a prominent feature of planets that is otherwise unexplained. Impact heating was mostly limited to planetary surfaces in the final stages of accretion. Frictional dissipation of spin contributed sufficient energy to ignite the primordial Sun and heated Earth and Venus by nearly as much as has the radioactive decay of K, U, and Th over geologic time. Energy inputs have been continuously offset by loss of heat to the surroundings. The magnitudes of most important energy contributions depend on the planet radius R and also on the distance r to the Sun. Quantitative, albeit approximate, relationships show that the net specific energy (kJ/kg) contributed to the rocky bodies over geologic time goes as: Earth ~ Venus &gt;&gt; Mars ~ Mercury ~ Moon &gt;&gt; asteroids. Net energy inputs increased the average internal temperatures of Earth and Venus by ~3000 K but heated asteroids by only a few hundred kelvins.
Study protocol of the COMPARE-Interaction study: the impact of maternal comorbid depression and anxiety disorders in the peripartum period on child development
Authors: Zietlow Anna-Lena , Woll Christian Franz Josef , Nonnenmacher Nora , Müller Mitho , Labonte Verena , Ditzen Beate , Paulus Markus , Sodian Beate , Nater Urs M , Herpertz Sabine C , Reck Corinna 
Published: January 2022

IntroductionTo date, there are only few studies that compare the consequences of peripartum maternal depressive disorders (PD) versus depressive with comorbid anxiety disorders (PDCA) for infant and child development. As comorbidity is associated with greater impairment and symptom severity related to the primary diagnosis, comorbidity in mothers might raise their offspring’s risk of developing internalising or externalising disorders even more than has been noted in conjunction with PD alone.Methods and analysisThis study aims to analyse the impact of parental psychopathology, particularly peripartum depression in mothers with and without comorbid anxiety disorders according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) on child cognitive and socioemotional development. Maternal/paternal psychopathology, mother–infant/father–infant interaction and child development are assessed at four measurement points over the first 2 years (T1: 3–4 months postpartum, T2: 12 months postpartum, T3: 18 months postpartum and T4: 24 months postpartum). The mediating role of mother–infant/father–infant interaction and infant stress reactivity in the relationship between PD/PDCA and infant cognitive and socioemotional development will be analysed. In the ongoing study, 174 families (n=58 mothers with PD, n=58 mothers with PDCA and n=58 healthy controls) will be recruited in inpatient and outpatient centres as well as maternity hospitals in Munich and Heidelberg.Ethics and disseminationThis study is implemented in accordance with the current guidelines of the World Medical Association (revised Declaration of Helsinki) and the General Data Protection Regulation of the European Union. The study procedures were approved by the independent ethics committees of the Department of Psychology, Ludwig-Maximilians-University Munich (74_Reck_b) and of the Medical Faculty, University Heidelberg (S-446/2017). Participation is voluntary. A signed written informed consent form must be obtained from each study subject prior to any study-specific procedure. Participants can withdraw from the study at any point in time without giving a reason or being subjected to any future disadvantages. In case of withdrawal from the study, the subject’s data and material will be kept unless the participant asks for data removal. Results will be published and disseminated to further the discussion on the effects of maternal PD and PDCA on parent–infant interaction, infant stress reactivity and child development. Furthermore, study results will be presented at international congresses and expert conferences.
Eosinopenia as a biomarker for antibiotic use in COPD exacerbations: protocol for a retrospective hospital-based cohort study
Authors: Yang Mei , Liu Xuemei , Hu Qiongqiong , Li Junjie , Fu Sijia , Chen Daohong , Wu Yanqing , Luo Ai , Zhang Xiawei , Feng Ruizhi , Xu Guo , Liu Can , Jiang Hongli , Liu Wei 
Published: January 2022

IntroductionThe acute exacerbation of chronic obstructive pulmonary disease (AECOPD) has a seriously negative impact on patients’ healths condition and disease progression. Bacterial infection is closely related to AECOPD, and antibiotics are frequently used in clinical practice. The lack of specific biomarkers for rational antibiotics use always leads to antibiotics abuse in chronic obstructive pulmonary disease (COPD) flare-ups. Eosinopenia has been considered to be related to increased bacterial load of potentially pathogenic organisms at the onset of COPD exacerbations. Therefore, this study aims to investigate whether eosinopenia could be used as a reference for the use of antibiotics in AECOPD.Methods and analysisIn this study, a hospital-based retrospective cohort design will be adopted to analyse the clinical data of inpatients who are primarily diagnosed with AECOPD in West China Hospital of Sichuan University from 1 January 2010 to 31 December 2020. Relevant data will be extracted from the Clinical Big Data Platform for Scientific Research in West China Hospital, including demographic characteristics, blood eosinophil count, procalcitonin, C reactive protein, microbial cultivation, antibiotics use, length of hospital stay, non-invasive ventilation use, intensive care unit transfer and mortality, etc. The collected data will be described and inferred by corresponding statistical methods according to the data type and their distributions. Multiple binary logistic regression models will be used to analyse the relationship between blood eosinophil count and bacterial infection. The antibiotics use, and patient morbidity and mortality will be compared between patients with or without eosinopenia.Ethics and disseminationThis study has been approved by the Biomedical Ethics Review Board of West China Hospital of Sichuan University (Approval No. 2020-1056). And the research results will be published in a peer-reviewed journal.Trial registration numberChiCTR2000039379.
Longitudinal survey on the Psychological Impact of the COVID-19 Pandemic in Healthcare Workers (PsyCOVer) in France: study protocol
Authors: Bertuzzi Leticia , El Aarbaoui Tarik , Heron Mégane , Gosselin Anne , Roy-de-Lachaise Laurine , Fossi Larissa , Della Corte Francesco , Vignier Nicolas , Melchior Maria , Schreiber Merritt , Vandentorren Stephanie , Vuillermoz Cécile 
Published: January 2022

IntroductionIn the pandemic, healthcare professionals face even higher levels of stress. It is therefore a priority to estimate the impact of the pandemic on mental health and to propose targeted strategies to improve resilience. The aims of the study were to (1) assess the mental health of healthcare professionals working with patients with COVID-19 and identify social determinants that may increase the risk of negative outcomes; and (2) test the effectiveness of an intervention to improve the resilience of healthcare professionals in France.Methods and analysisTo evaluate the first objective, a national longitudinal study will be carried out among healthcare professionals working with patients with COVID-19. Participants will be recruited via an internet link that will be widely disseminated on social media, mailing lists, medical boards and French medical journals. Primary outcomes are mental health distress/symptoms and resilience. Secondary outcomes are burnout, social and occupational supports and substance use. To meet the second objective, an interventional study will be conducted. The main outcome is the effectiveness of the PsySTART-Responder and the Anticipate.Plan.Deter program. Qualitative analyses will be conducted to understand the strategies used to cope with the pandemic.Ethics and disseminationThe study protocol was approved by the Sorbonne Université Ethical Committee (No 2020-CER-2020-27) and was declared to French Commission on Information Technology and Liberties, CNIL (N°2222413, 20-05-2021). The results of this study will provide a better understanding of mental health and social inequalities in mental health among healthcare professionals working in the pandemic; data about the effectiveness of the PsySTART-Responder and the Anticipate.Plan.Deter interventional program in France.
Implementing an evidence-based somatic acupressure intervention in breast cancer survivors with the symptom cluster of fatigue, sleep disturbance and depression: study protocol of a phase II randomised controlled trial
Authors: Wang Tao , Tan Jing-Yu (Benjamin) , Liu Xian-Liang , Zheng Si-Lin , Zhao Isabella , Eliseeva Sabina , Polotan Mary Janice , Cheng Hui-Lin , Huang Hou-Qiang 
Published: January 2022

IntroductionThe fatigue-sleep disturbance-depression (FSD) symptom cluster, as one of the most common symptom clusters in breast cancer (BC) survivors, can significantly decrease patients’ quality of life. Since the management of the FSD symptom cluster has been unsatisfactory with the use of pharmacological treatments alone, non-pharmacological approaches have, therefore, been recommended. Somatic acupressure (SA) is a promising approach given its potential benefits of cancer-related symptom alleviation and the convenience of self-practice. However, research evidence on using acupressure to manage the FSD symptom cluster has been limited. The proposed trial aims to examine the feasibility and preliminary effects of an evidence-based SA intervention for FSD symptom cluster management in BC survivors.Methods and analysisThis study will be a phase II randomised controlled trial with three study arms and 1:1:1 allocation. Fifty-one early-stage BC survivors who are experiencing the FSD symptom cluster will be randomly assigned to a true SA group, a sham SA group or a usual care group. All participants will receive an education booklet regarding FSD symptom cluster management advice as the usual care package. The participants in the true SA group will additionally receive a 7-week self-administered SA intervention. The participants in the sham SA group will additionally receive self-administered light acupressure at non-acupoints with the same frequency, session and duration as the true SA group. The primary outcomes will be feasibility outcomes related to subject recruitment and completion of study questionnaires and interventions. The secondary outcomes will be the effects of SA on fatigue, sleep disturbance, depression and quality of life. Descriptive statistics will be used to present all the outcomes. The secondary outcomes will be analysed using an intent-to-treat approach.Ethics and disseminationEthical approvals of this trial have been granted by the Human Research Ethics Committee at Charles Darwin University (H19017) and the Clinical Trial Ethics Committee at The Affiliated Hospital of Southwest Medical University (KY2019039). Findings from this trial will be published in peer-reviewed journals and presented at professional conferences.Trial registration numberThis trial was registered at ClinicalTrials.gov and the registration number is NCT04118140, with the stage at Recruiting.
Efektifitas Neuromuscular Taping (NMT) sebagai Terapi Non-Farmakologi pada Penderita Carpal Tunnel Syndrome di RS Saiful Anwar, Malang: Sebuah Laporan Kasus
Authors: Setianto Catur , Rahmy Septy , Sudjatmoko Azhar 
Published: January 2022

Pendahuluan: Carpal Tunnel Syndrome (CTS) adalah lesi saraf tepi yang sering ditemui karena mekanisme non-trauma. Metode terapi CTS bermacam-macam yang tujuannya untuk mengurangi keluhan dan meningkatkan produktivitas pasien. Salah satu metode non-farmakologi yang bisa digunakan adalah dengan Neuromuscular Tapping (NMT). Tujuan dari laporan kasus ini adalah untuk mengetahui efektivitas penggunaan NMT sebagai terapi non-farmakologi pada pasien CTS yang sebelumnya telah mendapatkan terapi farmakologis, diukur dengan skala NRS (Numeric Pain Rating Scale) pada pasien.
Ilustrasi Kasus: Wanita, 52 tahun, datang dengan keluhan kesemutan pada pergelangan tangan kanan dan kiri sejak 4 bulan dengan riwayat bekerja di pabrik rokok selama 10 tahun. Dari pemeriksaan fisik didapatkan nyeri pada pergelangan tangan kanan dan kiri dengan NRS 6-7, hipestesi pada jari 1, 2, 3, dan ½ jari 4 volar manus bilateral, pasien sudah mengkonsumsi obat anti nyeri dan nyeri membaik ketika mengkonsumsi obat namun akan kambuh kembali ketika tidak meminum obat. Pasien didiagnosa dengan Carpal Tunnel Syndrome bilateral (Rosenbaum level 2/ gejala persisten), pasien mendapat terapi farmakologis dengan pemberian NSAID (Nonsteroidal Anti-Inflammatory Drug) dan dilakukan injeksi kortikosteroid namun belum menunjukkan perbaikan nyeri yang kemudian pasien dilakukan NMT sebagai terapi non-farmakologi.
Pembahasan: Hasil tindak lanjut pasien setelah menjalani terapi NMT, didapatkan perbaikan dari keluhan pasien yang terlihat dari perbaikan skor NRS pasien.
Certainty-based Preference Completion
Authors: Li Lei , Xue Minghe , Zhang Zan , Chen Huanhuan , Wu Xindong 
Published: January 2022

Abstract
As from time to time it is impractical to ask agents to provide linear orders over all alternatives, for these partial rankings it is necessary to conduct preference completion. Specifically, the personalized preference of each agent over all the alternatives can be estimated with partial rankings from neighboring agents over subsets of alternatives. However, since the agents' rankings are nondeterministic, where they may provide rankings with noise, it is necessary and important to conduct the certainty-based preference completion. Hence, in this paper firstly, for alternative pairs with the obtained ranking set, a bijection has been built from the ranking space to the preference space, and the certainty and conflict of alternative pairs have been evaluated with a well-built statistical measurement Probability-Certainty Density Function on subjective probability, respectively. Then, a certainty-based voting algorithm based on certainty and conflict has been taken to conduct the certainty-based preference completion. Moreover, the properties of the proposed certainty and conflict have been studied empirically, and the proposed approach on certainty-based preference completion for partial rankings has been experimentally validated compared to state-of-arts approaches with several datasets.