bluuebunny/crossref_metadata_2025_split huggingface dataset:
Endonasal transsphenoidal surgery for planum sphenoidale versus tuberculum sellae meningiomas
Authors: Henderson Fraser , Youngerman Brett E. , Niogi Sumit N. , Alexander Tyler , Tabaee Abtin , Kacker Ashutosh , Anand Vijay K. , Schwartz Theodore H. 
Published: October 2022

OBJECTIVE
The aim of this study was to determine if the distinction between planum sphenoidale (PS) and tuberculum sellae (TS) meningiomas is clinically meaningful and impacts the results of the endoscopic endonasal approach (EEA).

METHODS
A consecutive series of patients who were 18 years of age or older and underwent EEA for newly diagnosed grade I PS meningiomas (PSMs) and TS meningiomas (TSMs) between October 2007 and May 2021 were included. The PS and TS were distinguished by drawing a line passing through the center of the TS and perpendicular to the PS on postcontrast T1-weighted MRI. Probabilistic heatmaps were created to display the actual distribution of tumor volumes. Tumor volume, extent of resection (EOR), visual outcome, and complications were assessed.

RESULTS
The 47 tumors were distributed in a smooth continuum. Using an arbitrary definition, 24 (51%) were PSMs and 23 (49%) were TSMs. The mean volume of PSMs was 5.6 cm3 compared with 4.5 cm3 for TSMs. Canal invasion was present in 87.5% of PSMs and 52% of TSMs. GTR was achieved in 38 (84%) of 45 cases in which it was the goal, slightly less frequently for PSMs (78%) compared with TSMs (91%), although the difference was not significant. Th mean EOR was 99% ± 2% for PSMs and 98% ± 11% for TSMs. Neither the suprasellar notch angle nor the percentage of tumor above the PS impacted the rate of GTR. After a median follow-up of 28.5 months (range 0.1–131 months), there were 2 (5%) recurrences after GTR (n = 38) both of which occurred in patients with PSMs. Forty-two (89%) patients presented with preoperative impaired vision. Postoperative vision was stable or improved in 96% of patients with PSMs and 91% of patients with TSMs. CSF leakage occurred in 4 (16.6%) patients with a PSM, which resolved with only lumbar drainage, and in 1 (4.3%) patient with a TSM, which required reoperation.

CONCLUSIONS
PSM and TSMs arise in a smooth distribution, making the distinction arbitrary. Those classified as PSMs were larger and more likely to invade the optic canals. Surgical outcome for both locations was similar, slightly favoring TSMs. The arbitrary distinction between PSMs and TSMs is less useful at predicting outcome than the lateral extent of the tumor, regardless of the site of origin.
Rationalization of Reloading Cranes at Container Terminals of Freight Stations
Authors:   Ukrainian State University of Railway Transport (UkrDURT), Kryachko Kateryna , Kuleshov Valerii ,   Ukrainian State University of Railway Transport (UkrDURT), Shramko A. ,   Ukrainian State University of Railway Transport (UkrDURT)
Published: October 2022

The article considers the issue of efficiency of technical equipment of container terminals and rationalization of handling facilities and economic justification of their required number for the estimated service life, taking into account the allocation of investments in conditions of limited resources.	One of the main problems of optimal control of reloading processes is the choice of a rational strategy for controlling loading and unloading machines within the work cycle, when the range of their movement at design speeds and accelerations is crucial given the constraints imposed on control parameters determined by design and operational conditions (permissible speeds and accelerations for a particular cargo front, maximum traction, operational productivity, site capacity, etc.). The optimization criteria can be the cost parameters for performing the basic operations of the operating cycle, taking into account energy costs depending on the range of loading and unloading machines.	In the case where the container site is serviced by several handling equipment, the downtime of one group of cars depends on the downtime of other handling facilities.	At existing freight stations, the length of container sites ranges from 100 to 300 m and more. The intensity of use of the length of the cargo front is very small, which causes a large amount of shunting work, interoperable downtime of loading and unloading machines and rolling stock.	Thus, the introduction of rational control technology for loading and unloading facilities should be consistent with the design of the cargo station and container terminal, which would allow to fully implement all the design parameters with the lowest operating costs.
WAYS OF CHANGING THE STRUCTURAL-MORPHOLOGICAL, PHYSICO-CHEMICAL AND ELECT­RICAL PROPERTIES OF GRAPHENES
Authors: Panteleimonov Radyslav 
Published: October 2022

A literature analysis of sources on synthesis methods and their influence on the structural-morphological, physico-chemical, and electrochemical properties of graphene and graphene-like structures was carried out. It was established that these properties have a clear dependence on the synthesis method, starting materials, and the composition of the synthesis medium.
The main ways of changing graphene's structural-morphological, physico-chemical and electrical properties are changes in the synthesis method and conditions that affect the formation of σ-bonds and π-bonds. The presence of these bonds regulates the number of graphene layers and the formation of van der Waals interactions between them, as well as the formation of edge structural defects responsible for electrokinetic and catalytic properties. Changing the gas medium to a liquid one greatly simplifies the synthesis of graphene. Still, in the case of a liquid nitrogen medium, simultaneously with a 2-dimensional structure, it is possible to form 3-dimensional particles up to tens of nanometers in size. Aqueous medium and plasma-arc synthesis methods are the most attractive for obtaining materials with electron-donor conductivity, which have attractive electrochemical and catalytic properties for use in chemical current sources and fuel cells. Using an aqueous environment requires mandatory further heat treatment at temperatures above 250 0C to se­parate chemisorbed water from the structure, which complicates the synthesis procedure. The advantage of the plasma-arc method for the synthesis of graphene and other carbon nanostructures is its ability to shorten the stages of the synthesis of graphene, the possibility of modifying them directly during the synthesis process by changing the environment, easy management, and obtaining a clean final pro­duct. In the modern practice, this method is limited to obtaining coatings on a solid carrier.
KINETICS OF HARDENING OF EPOXY-AMINE SYSTEMS DOPED WITH LiClO4
Authors: Demchenko Valeriy , Matkovska Liubov , Matkovska Оlga 
Published: October 2022

Kinetic methods for analyzing the curing process of thermosetting polymer systems are an important area for controlling the formation conditions for viscosity, which depends on the temperature and chemical composition of the composite. The curing reactions determine the morphology and structure of the system, affecting the properties of the final material. This work analyzes the curing process of po­lymer composites based on epoxy oligomer - polyethylene glycol diglycidyl ether (DEG), polyethylene polyamine hardener (PEPA) and lithium perchlorate salt LiClO4. The initial components, the mixture of DEG/PEPA composition and the DEG/PEPA/LiClO4 system supplemented with salt were investigated. Using the methods of Fourier-transform infrared spectroscopy and rheological analysis in dynamic mode the curing conditions of the systems were established. It was shown that the nature of the distribution of vibration bands in the IR spectra of the DEG/PEPA and DEG/PEPA/LiClO4 systems is a superposition of the IR spectra of the initial components. Lithium perchlorate in the salt-doped initial system is in an undissociated state and dissociates in the polymer matrix over time during the curing of the system. In particular, the time dependences of the concentration of epoxide groups in the DEG/PEPA system calculated using the integral intensity ratios were analyzed by IR spectroscopy data. To study the curing process with increased segmental mobility of the reacting macromolecules, rheokinetic measurements were performed at 50°C. Analysis of the nature of changes in the elastic and viscosity moduli over time allowed us to estimate the gel time of the initial and doped systems. Differences in the IR spectra for both systems before the formation of the three-dimensional structure and at the gel point, as well as the IR spectra of these systems after the curing reaction, were analyzed. Attention was also paid to the nature of the influence of dopant on the curing process and its state in the mixture/composite of DEG/PEPA/LiClO4 composition. Lithium perchlorate LiClO4 is an effective catalyst for the aminolysis of the oxirane ring, which explains the acceleration of the curing reaction of the system in the presence of salt.
Penyuluhan tentang Pentingnya Menjaga Protokol Kesehatan pada Masa Pandemi di Panti Asuhan Al-Kaaf Jabung Kabupaten Malang
Authors: Fitri  , Herman Hariyadi  , Leonardo Kamajaya  , Lucky Nindya Palupi  , Muhammad Khairuddin  
Published: October 2022

The implementation of counseling about the importance of health protocols during the pandemic was carried out at the Al-Kaaf Jabung Orphanage, Malang Regency. The equipment used is a laptop, hand sanitizer, masks, and soap for washing hands. The method of this counseling is the tutorial through the zoom meeting application, followed by the students and orphanage administrators, because it is still in the pandemic period. The speakers in this activity are the teaching staff of the Electrical Engineering Department, State Polytechnic of Malang who in this case are members of this PkM activity and are assisted by students of State Polytechnic of Malang. The results of this dedication, it is hoped that the participants apply 5M in their daily life so that they can break the chain of the spread of COVID-19.
Production of biopolymer precursors beta-alanine and L-lactic acid from CO2 with metabolically versatile Rhodococcus opacus DSM 43205
Authors: Salusjärvi Laura , Ojala Leo , Peddinti Gopal , Lienemann Michael , Jouhten Paula , Pitkänen Juha-Pekka , Toivari Mervi 
Published: October 2022

Hydrogen oxidizing autotrophic bacteria are promising hosts for conversion of CO2 into chemicals. In this work, we engineered the metabolically versatile lithoautotrophic bacterium R. opacus strain DSM 43205 for synthesis of polymer precursors. Aspartate decarboxylase (panD) or lactate dehydrogenase (ldh) were expressed for beta-alanine or L-lactic acid production, respectively. The heterotrophic cultivations on glucose produced 25 mg L−1 beta-alanine and 742 mg L−1 L-lactic acid, while autotrophic cultivations with CO2, H2, and O2 resulted in the production of 1.8 mg L−1 beta-alanine and 146 mg L−1 L-lactic acid. Beta-alanine was also produced at 345 μg L−1 from CO2 in electrobioreactors, where H2 and O2 were provided by water electrolysis. This work demonstrates that R. opacus DSM 43205 can be engineered to produce chemicals from CO2 and provides a base for its further metabolic engineering.
Microwave-assisted synthetic method of novel Bi2O3 nanostructure and its application as a high-performance nano-catalyst in preparing benzylidene barbituric acid derivatives
Authors: Yahyazadehfar Mahdieh , Sheikhhosseini Enayatollah , Ahmadi Sayed Ali , Ghazanfari Dadkhoda 
Published: October 2022

In this study, controllable and optimal microwave irradiation has been used to synthesize the novel nanostructures of Bi2O3 under environmental conditions. The final products had a thermal stability of 210°C, an average particle size distribution of 85 nm, and a surface area of 783 m2/g. The high thermodynamic stability of Bi2O3 nanostructures was confirmed by TG and differential scanning calorimetry (DSC) analyses. The nanostructure nature of compounds, and most importantly, the use of an effective, cost-effective, and rapid synthesis route of microwave have created significant physiochemical properties in the Bi2O3 products. These unexpected properties have made the possibility of potential application of these products in various fields, especially in nano-catalyst applications. It is well-documented that, as Lewis acid, bismuth nano-catalyst exhibits a great catalytic activity for the green synthesis of some bio-active barbituric acid derivatives using precursors with electron-donating or electron-withdrawing nature in high yields (80%–98%). After incorporating this catalyst into the aqueous media, all the reactions were completed within 2–3 min at room temperature. The main advantages of this method are practical facility, the availability of starting materials, and low costs besides the catalyst reusability. Additionally, the catalyst synthesis process may be carried out in the aqueous media for a short period with medium to high yields. The obtained results have opened a new window for the development of a novel nano-catalyst with practical application.
Entamoeba gingivalis is associated with periodontal conditions in Chinese young patients: A cross-sectional study
Authors: Jiao Junwei , Bie Mengyao , Xu Xin , Duan Dingyu , Li Yan , Wu Yafei , Zhao Lei 
Published: October 2022

BackgroundThis study investigated the prevalence and relative abundance of Entamoeba gingivalis (E. gingivalis) in Chinese young patients with different periodontal conditions, and its association with subgingival microbial composition, periodontal parameters, and cytokines in gingival crevicular fluid.MethodsParticipants (age: 18–45 years) diagnosed with stage II–IV periodontitis, gingivitis, or periodontal health underwent periodontal examination and sampling. Subgingival plaque was analyzed by 16S+18S sequencing for E. gingivalis detection and microbial analysis. The distribution of E. gingivalis in subgingival plaque was illustrated by fluorescence in situ hybridization. Interleukin-1β, interleukin-8, and tumor necrosis factor-α in gingival crevicular fluid were measured by multiplexed flow cytometric assay.ResultsThis cross-sectional study included 120 sites from 60 participants. The prevalence and relative abundance of E. gingivalis were significantly increased in periodontitis (p&lt;0.05). The sites were classified into three subgroups according to the relative abundance of E. gingivalis: negative group (Eg0, n=56); low-abundance group (Eg1, n=32); and high-abundance group (Eg2, n=32). The subgingival microflora in the subgroups showed stepwise changes at both the phylum and genus levels. The microflora compositions were significantly altered from Eg0 to Eg2 (p&lt;0.001). Co-occurrence network analysis showed that Porphyromonas, Treponema, Tannerella, Filifactor, TG5, and Desulfobulbus were highly correlated with E. gingivalis (r&gt;0.6, p&lt;0.001). Correlation analysis showed that E. gingivalis was closely associated with important periodontal parameters and cytokines (p&lt;0.01).ConclusionE. gingivalis was enriched in periodontitis and closely associated with subgingival microbial dysbiosis, periodontal parameters and cytokines in gingival crevicular fluid. Thus, it may be an important pathogen in periodontal disease.
Ovarian stimulation in IVF couples with severe male factor infertility: GnRH antagonist versus long GnRH agonist
Authors: Lv Mu , Yu Juanjuan , Chen Peiqin , Xiao Qimeng , Lou Liqun , Luo Yifan , Yuan Mu , Xu Yuan , Feng Youji , Bai Mingzhu , Zhang Zhenbo , Li Linxia 
Published: October 2022

ObjectiveTo examine the efficacy of gonadotropin releasing hormone (GnRH) antagonist (GnRH-ant) protocol and the long GnRH agonist (GnRH-a) protocol during in vitro fertilization (IVF) therapy in patients with severe male infertile factors.MethodsA total of 983 women with severe male factor infertility undergoing IVF therapy from 2017 to 2020 at one center were retrospectively analyzed. Patients were divided into the GnRH-ant group (n=527) and the GnRH-a group (n=456) according to their ovarian stimulation protocols. Patient baseline characteristics, ovarian stimulation characteristics, and clinical pregnancy outcomes were compared between the groups. The live birth rate was considered the main pregnancy outcome.ResultsGnRH-a group had a higher live birth rate compared with the GnRH-ant group (41.0% versus 31.3%, p=0.002). Moreover, the implantation (32.8% vs. 28.1%, p=0.033), biochemical pregnancy (52.4% versus 44.8%, p=0.017), clinical pregnancy (49.3% versus 39.7%, p=0.002) and ongoing pregnancy rates (43.2% vs. 34.9%, p=0.008) were higher in GnRH-a group. For patients with one embryo transferred, the GnRH-a group demonstrated higher live birth (37.0% vs. 19.4%, p=0.010) and ongoing pregnancy rate (38.9% vs. 24.5%, p=0.046) than the GnRH-ant group. Among patients with two embryos transferred, the live birth rate was also higher in the GnRH-a group than in the GnRH-ant group, with no statistical difference. No significant differences were observed in the biochemical abortion rate, clinical miscarriage rate, early miscarriage rate, late miscarriage rate, heterotopic pregnancy rate, twin pregnancy rate, and birth sex ratio between the two groups.ConclusionFor individuals with severe male infertility undergoing IVF, the GnRH-a protocol is considered a more efficient and feasible strategy with a higher live birth rate compared to the GnRH-ant protocol, especially in single embryo transfer.
Diagnosing pancreatic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1 in daily practice
Authors: van Beek Dirk-Jan , Pieterman Carolina R. C. , Wessels Frank J. , van de Ven Annenienke C. , de Herder Wouter W. , Dekkers Olaf M. , Zandee Wouter T. , Drent Madeleine L. , Bisschop Peter H. , Havekes Bas , Borel Rinkes Inne H. M. , Vriens Menno R. , Valk Gerlof D. 
Published: October 2022

BackgroundIn multiple endocrine neoplasia type 1 (MEN1), pancreatic neuroendocrine tumors (PanNETs) have a high prevalence and represent the main cause of death. This study aimed to assess the diagnostic accuracy of the currently used conventional pancreatic imaging techniques and the added value of fine needle aspirations (FNAs).MethodsPatients who had at least one imaging study were included from the population-based MEN1 database of the DutchMEN Study Group from 1990 to 2017. Magnetic resonance imaging (MRI), computed tomography (CT), endoscopic ultrasonography (EUS), FNA, and surgical resection specimens were obtained. The first MRI, CT, or EUS was considered as the index test. For a comparison of the diagnostic accuracy of MRI versus CT, patients with their index test taken between 2010 and 2017 were included. The reference standard consisted of surgical histopathology or radiological follow-up.ResultsA total of 413 patients (92.8% of the database) underwent 3,477 imaging studies. The number of imaging studies per patient increased, and a preference for MRI was observed in the last decade. Overall diagnostic accuracy was good with a positive (PPV) and negative predictive value (NPV) of 88.9% (95% confidence interval, 76.0–95.6) and 92.8% (89.4–95.1), respectively, for PanNET in the pancreatic head and 92.0% (85.3–96.0) and 85.3% (80.5–89.1), respectively, in the body/tail. For MRI, PPV and NPV for pancreatic head tumors were 100% (76.1–100) and 87.1% (76.3–93.6) and for CT, 60.0% (22.9–88.4) and 70.4% (51.3–84.3), respectively. For body/tail tumors, PPV and NPV were 91.3% (72.0–98.8) and 87.0% (75.3–93.9), respectively, for MRI and 100% (74.9–100) and 77.8% (54.3–91.5), respectively, for CT. Pathology confirmed a PanNET in 106 out of 110 (96.4%) resection specimens. FNA was performed on 34 lesions in 33 patients and was considered PanNET in 24 [all confirmed PanNET by histology (10) or follow-up (14)], normal/cyst/unrepresentative in 6 (all confirmed PanNET by follow-up), and adenocarcinoma in 4 (2 confirmed and 2 PanNET). Three patients, all older than 60 years, had a final diagnosis of pancreatic adenocarcinoma.ConclusionAs the accuracy for diagnosing MEN1-related PanNET of MRI was higher than that of CT, MRI should be the preferred (non-invasive) imaging modality for PanNET screening/surveillance. The high diagnostic accuracy of pancreatic imaging and the sporadic occurrence of pancreatic adenocarcinoma question the need for routine (EUS-guided) FNA.
Conservation tillage and residue management improve soil health and crop productivity—Evidence from a rice-maize cropping system in Bangladesh
Authors: Sarker Mamunur Rashid , Galdos Marcelo Valadares , Challinor Andrew J. , Huda Muhammad Shamsul , Chaki Apurbo K. , Hossain Akbar 
Published: October 2022

The rice-maize (R-M) system is rapidly expanding in Bangladesh due to its greater suitability for diverse soil types and environments. The present conventional method of cultivating puddled transplanted rice and maize is input-intensive, decreases soil health through intense ploughing, and ultimately reduces farm profitability. There is a need to investigate alternatives. Accordingly, we conducted a replicated 2-year (2020–2021) field study to investigate the effects of conservation agriculture (CA) based tillage and crop establishment (TCE) techniques and residue management practices on the physical, chemical, and biological properties of soil along with crop productivity and the profitability of rice-maize systems in the sandy loam soil of Northwest Bangladesh. Two TCE techniques Puddled transplanted rice (PTR) followed by Conventional tillage maize (CTM) and strip tillage direct-seeded rice (STDSR) followed by strip-tilled maize (STM) were assigned to the main plots and different percentages of crop residue retention (0, 25, and 50% by height) were allocated to the subplots. Results showed that a reduction in bulk density (BD), soil penetration resistance (SPR), and increased soil porosity were associated with STDSR/STM-based scenarios (strip tillage coupled with 25 and 50% residue retention). The soil organic carbon (SOC) fractions, such as dissolved organic C (DOC), light and heavy particulate organic matter C (POM-C), MAOM, and microbial biomass C (MBC) levels in the 0–10 cm layer under ST based treatments were 95, 8, 6, 2 and 45% greater, respectively, compared to CT with no residue treatment. When compared to the CT treatment, the DOC, light POM-C, heavy POM-C, and MAOM in the 10–20 cm layer with ST treatment were 8, 34, 25, 4 and 37% higher, respectively. Residue retention in ST increased average rice, maize, and system yields by 9.2, 14.0, and 14.12%, respectively, when compared to CT. The system gross margin and benefit-cost ratio (BCR) were $1,515 ha−1 and 1.90 under conventional tillage to $1,696 ha−1 and 2.15 under strip-tillage practices. Thus, our study suggests that CA could be an appropriate practice for sustaining soil fertility and crop yield under R-M systems in light-textured soils or other similar soils in Bangladesh.