bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physically based modelling techniques for landslide susceptibility analysis: A comparison
Authors: Meena V , Kumari S , Shankar V 
Published: July 2022

Abstract
In mountainous areas, landslides are the most common natural catastrophic event, due to these events thousands of people are killed each year, and millions of dollars are lost in property damage. Landslides are mainly induced by earthquakes, rainfall, or manmade activities. Several GIS techniques, such as synthetic aperture radar, ranging data from spaceborne, airborne, and ground-based platforms, optical, and light detection and various physically based models such as SINMAP, TRIGRS, SHALSTAB etc. have been widely used to study slope failures in recent years. Each of these techniques has advantages and limitations for susceptibility analysis of landslides. The current research focuses on landslide susceptibility models that are physically based, their parameterization and working principle. The study infers that TRIGRS is the most commonly used model for slope stability analysis, whereas GEO top model is the only 3D slope stability model which considers the spatial variation of soil parameters hence it can be considered as the most advanced physically based slope stability model.
Spatial variation of Physico-chemical parameters and water quality assessment of urban ponds at Raipur, Chhattisgarh, India
Authors: Tamrakar Anjali , Upadhyay Kshitij , Bajpai Samir 
Published: July 2022

Abstract
Water bodies, natural or man-made, are under threat due to rapid urbanization. This research paper assesses the water quality of 20 ponds located in the vicinity of urban habitats of Raipur district, Chhattisgarh (India) using the Water Quality Index (WQI). The samples were analyzed for 16 physicochemical parameters in the post-monsoon winter season. The parameters were used to calculate WQI and the ponds were categorized accordingly for end use purposes, that is, drinking, irrigation, industrial, or unfit for use without treatment. The WQI of post-monsoon samples resulted in that 75% of the total pond water samples are in excellent condition, & 25% of the samples are unfit for various activities like drinking, irrigation, industrial & domestic. A high value of nutrients was observed in all the ponds, suggesting that the nutrient entering through surface runoff, solid waste disposal, and wastewater is entering the ponds. Our results conclude that all ponds require interventional steps to restore pond water quality and stop it from further degradation, determining which trophic state of the ponds may change in the future. The spatial monitoring of physical and chemical properties of pond water helps to predict, identify, and assess the natural condition of the urban ponds and their relation with the surrounding (environment) and helps in adopting rejuvenation measures.
Kodagu disaster (Floods - Emphasis on Catchment Fragmentation Index and unscientific land usage) analysis using GIS
Authors: Kushal M , Barman Sangita Deb 
Published: July 2022

AbstractIndia is a densely populated country, natural hazards like floods and landslides cause a great impact on peoples’ life and property as well. The floods and landslides in Kodagu, Karnataka was not only because of unexpected heavy rain but has various man-made causes like unscientific land-usage modifications. This unscientific land usage and linear constructions like roads railways, etc. have caused catchment fragmentation, hindered or blocked the natural streamflow, and resulted in localized water stagnation, resulting in floods and landslides. This paper defines an index-catchment fragmentation index to generalize the causes of both unscientific land usage and linear constructions (mainly roads). Catchment fragmentation causes variations in soil moisture content, flow path, flow velocity, flow connectivity, as well as on concentration time. This paperuses the Multi-Criteria Decision Making-Analytical hierarchy process (MCDM-AHP) to create a flood hazard zonation map and also aims at predicting the hazard and vulnerability zones and hence triesto guide on correcting the unscientific land usages.
Advancement of Environmental Concerns Through Cli-Fi: James Bradley’s Clade as a Prototype
Authors: Manjhi Anil 
Published: July 2022

Abstract
Climate Change due to anthropogenic factors and its repercussions in the form of disastrous environmental calamities is the burning issue in the current scenario. People of different fields are trying every possible means to bring awakening in the populace. The field of literature is also making contributions to this noble cause. Cli-fi or Climate Change Fiction is the newfangled branch of Ecocriticism from the field of literature, which is entirely dedicated to dealing with and bringing up climate change problems, global warming and likewise. The impact of this genre of literature has brought up the positive impact on the wider range of the population in simple language as compared to that of the technical language. Thus, this research study aims to bring forth the advancement of environmental concern employing Cli-fi or Climate Change Fiction by analysing James Bradley’s work Clade as a prototype and inclusively quoting other key literary works in this genre and their primary contributions made in this field of operation. The narrative technique with vivid descriptions, the mapping of the psychological awakening of emotions towards environmental concern and the portrayal of environmental calamities will pave the way and establish the advanced approach of literature for environmental concern and climate change.
3D Monitoring & its Significance in Tunneling: Special Emphasis on Tunnel T-74R of USBRL Project, India
Authors: Ahmed A , Mishra S , Singh A K , Azad A 
Published: July 2022

Abstract
Nowadays, Tunnels are the major transportation network throughout the world. The importance of tunnel and its associated system also increases as the demand of Tunnel construction increases day by day. It has its significant importance in water conveyance networks as well as communication networks. As it is spreading fast over the world, the assessments of deformations are becoming an important part of tunneling system. The paper deals with the 3D monitoring system for the safety perspective and to make proper judgement about the condition of tunnels related to the information obtained in the measuring equipments. It also enables to react under various rock setting with the precise and reliable monitoring results. As we observed in the T-74R tunnel, where deformation of the tunnel’s support system is a natural occurrence, the T-74R’s main support system was also affected. The groundmass is prone to deformation due to its poor state and proximity to the principal thrust. The finding of the T-74R tunnel utilising 3D monitoring devices is important. They have provided the information about actual ground behaviour conditions.
Assessment of active tectonics in the Siwalik basin around the Subansiri river, NE India
Authors: Singh Archana , Gogoi Bijoylakshmi , Bezbaruah Devojit , Singh Neelratan 
Published: July 2022

Abstract
In this paper we evaluate the morphotectonics of the area around the Subansiri river in north-eastern India. Research focuses on understanding the impacts on areas experiencing active tectonic deformation. It also explains the variety of kinematics observed in the area from the Miocene to the present. The tectonics can explain some structures related to the extensional tectonics predominant in the region and the development of the minor and major morph structures driven by faults with different kinematics. We developed a morphotectonic evolutionary model for the area based on the morphotectonic analysis and geological mapping. Morphotectonic indices used to evaluate the tectonic activeness in this study are Mountain Front sinuosity Index, Valley Floor Width to Valley Height Ratio, Asymmetry Factor, Transverse Topographic Symmetry Factor, Mountain Front Steepness Index, Basin Shape Index and Stream Length Gradient Index. There are numerous lineaments present in the study area which are trending in NW-SE and NE-SW direction.
Research on shear strength of geopolymer concrete by using fly ash
Authors: Daur Sachin A. , Sinha Madhulika 
Published: July 2022

Abstract
Cement is one of the most important construction material. Cement is a backbone of civil engineering work. Development of whole world depends upon increasing infrastructure. For which cement is very necessary. Manufacturing of cement produce huge amount of carbon di-oxide and other greenhouse gases which is hazardous to the environment causes pollution. Hence it is very necessary to develop alternative binding material instead of cement for construction. Many researchers contribute their work on replacement of cement in concrete.
Development of different hydrogeological influencing thematic layers and groundwater potential zones of Deo river watershed of Mayurbhanj district, Odisha, India
Authors: Mohanta N K , Jhariya D C , Mawale Y K , Sahu M 
Published: July 2022

Abstract
Water is one of the most abundant renewable resources, and it is essential to all living things. Groundwater is one of the major sources of Water in the planet Earth. Continuous uses of water without any conservation cause lowering of Ground water level and thus living forms are facing many problems now-a-days. Due to increase in industrialisation in the state of Odisha water problem is rising its head. Using Remote Sensing and Geographic information system (GIS) methods, this research aids in the delineation of water potential zones in the Deo river watershed in Mayurbhanj district, odisha. For this, different thematic layers have been prepared and interpreted. This study may be helpful to monitor and conserve groundwater in near future.
Improving plasma sterilization by constructing a plasma photocatalytic system with a needle array corona discharge and Au plasmonic nanocatalyst
Authors: ZHU 朱 Bin 斌 , LI 李 Qiwei 其玮 , GAO 高 Yanan 亚楠 , YAN 闫 Yan 妍 , ZHU 朱 Yimin 益民 , XU 徐 Li 力 
Published: July 2022

Abstract
Efficient sterilization by a plasma photocatalytic system (PPS) requires strong synergy between plasma and photocatalyst to inactivate microorganisms while suppressing the formation of secondary pollutants. Here, we report that a PPS constructed from a needle array corona discharge and Au/TiO2 plasmonic nanocatalyst could remarkably improve the sterilization of Escherichia coli (E. coli) and alleviate formation of the discharge pollutant O3. At 6 kV, the combination of corona discharge and Au/TiO2 achieves sterilization efficiency of 100% within an exposure time of 5 min. At 5 kV and an exposure time of 8 min, the presence of Au/TiO2 improves sterilization efficiency of the corona discharge from 73% to 91% and reduces the O3 concentration from 0.38 to 0.04 ppm, whereas the presence of TiO2 reduces the sterilization efficiency and O3 concentration to 66% and 0.17 ppm, respectively. The Au/TiO2 in the PPS enables a uniform corona discharge, enhances the interaction between plasma, E. coli and nanocatalysts, and suppresses the formation of O3. Further, the Au/TiO2 can be excited by ultraviolet–visible light emitted from the plasma to generate electron–hole pairs, and thus contributes to the formation of reactive radicals and the oxidative inactivation of E. coli. The PPS constructed from a needle array corona discharge and Au-based plasmonic nanocatalyst provides a promising approach for developing high-efficiency sterilization techniques.
Impact of comprehensive geriatric assessment on the risk of adverse events in the older patients receiving anti-cancer therapy: a systematic review and meta-analysis
Authors: Chuang Min-Hsiang , Chen Jui-Yi , Tsai Wen-Wen , Lee Chia-Wei , Lee Mei-Chuan , Tseng Wen-Hsin , Hung Kuo-Chuan 
Published: July 2022

Abstract

Background
to assess the efficacy of comprehensive geriatric assessment (CGA) for preventing treatment-related toxicity in older people undergoing non-surgical cancer therapies.

Methods
MEDLINE, EMBASE and Cochrane library databases were searched from inception till January 2022 to identify randomised controlled trials (RCTs) on the incidence of toxicity measured by the Common Terminology Criteria for Adverse Events (primary outcome) and that of therapeutic modifications, early treatment discontinuation, progression-free survival, overall survival and hospitalisation (secondary outcomes).

Results
analysis of six RCTs published from 2016 to 2021 recruiting 2,126 participants (median age: 71–77) who received chemotherapy as the major therapeutic approach revealed 51.7% and 64.7% of Grade 3+ toxicity in the CGA and control (i.e. standard care) groups, respectively (RR = 0.81, 95% CI: 0.7–0.94, P = 0.005, I2 = 65%, certainty of evidence [COE]: moderate). There were no significant differences in the incidence of early treatment discontinuation (RR = 0.88, P = 0.47; I2 = 63%,1,408 participants, COE: low), initial reduction in treatment intensity (RR = 0.99, P = 0.94; I2 = 83%, 2055 participants, COE: low), treatment delay (RR = 1.06, P = 0.77, I2 = 0%, 309 participants, COE: moderate), hospitalisation (RR = 0.86, P = 0.39, I2 = 41%, 914 participants, COE: moderate), progression-free and overall survival with or without CGA. However, there was an association between CGA and a lower incidence of dose reduction during treatment (RR = 0.73, P &lt; 0.00001, 956 participants, COE: moderate).

Conclusions
our results demonstrated that comprehensive geriatric assessment may be associated with a lower incidence of treatment-related toxicity and dose reduction compared to standard care in older people receiving non-surgical cancer treatments. Further large-scale studies are warranted to support our findings.
The UN Decade of healthy ageing: strengthening measurement for monitoring health and wellbeing of older people
Authors: Amuthavalli Thiyagarajan Jotheeswaran , Mikton Christopher , Harwood Rowan H , Gichu Muthoni , Gaigbe-Togbe Victor , Jhamba Tapiwa , Pokorna Daniela , Stoevska Valentina , Hada Rio , Steffan Grace Sanico , Liena Ana , Rocard Eileen , Diaz Theresa 
Published: July 2022

Abstract
Over the past 100 years, life expectancy has increased dramatically in nearly all nations. Yet, these extra years of life gained have not all been healthy, particularly for older people aged 60 years and over. In 2020, the World Health Organisation (WHO) and United Nations (UN) member states embraced a sweeping 10-year global plan of action to ensure all older people can live long and healthy lives, formally known as the UN Decade of Healthy Ageing (2021–2030). With the adoption of the UN Decade of Healthy Ageing resolution, countries are committed to implementing collaborative actions to improve the lives of older people, their families and the communities in which they reside. The Decade addresses four interconnected areas of action. Adopting the UN's resolution on the Decade of Healthy Ageing has caused excitement, but a question that has weighed on everyone's mind is how governments will be held accountable? Besides, there have been no goals or targets set for the UN Decade of Healthy Ageing from a programmatic perspective for the action areas, and guidance on measures, data collection, analysis and reporting are urgently needed to support global, regional and national monitoring of the national strategies, programmes and policies. To this end, WHO in collaboration with UN agencies and international agencies established a Technical Advisory Group for Measurement of Healthy Ageing (TAG4MHA) to provide advice on the measurement, monitoring and evaluation of the UN Decade of Healthy Ageing at the global, regional and national levels.
Impact of pharmacist participation in the patient care team on value-based health measures
Authors: Patti Michael , Colmenares Evan W , Abrahamson Anna , Weddle Sarah , Cavanaugh Jamie , Deyo Zack , Vest Mary-Haston 
Published: July 2022

Abstract

Purpose
To evaluate whether pharmacist engagement on the interdisciplinary team leads to improved performance on diabetes-related quality measures.

Methods
This was a retrospective observational study of patients seen in primary care and specialty clinics from October 2014 to October 2020. Patients were included if they had a visit with a physician, nurse practitioner, physician’s assistant, or clinical pharmacist practitioner (CPP) within the study period and had a diagnosis of diabetes. The intervention group included patients with at least one visit with a CPP, while the control group consisted of patients who were exclusively managed by non-CPP providers. The primary outcome of this study was the median change in glycosylated hemoglobin (HbA1c) from baseline to follow-up at 3, 6, and 12 months. The secondary outcome was the probability of achieving the HbA1c targets of &lt;7% and &lt;8% at 3, 6, and 12 months.

Results
Patients referred to a CPP had higher HbA1c levels at baseline and were more likely to have concomitant hypertension (P &lt; 0.01). Patients seen by a CPP had 0.31%, 0.41%, and 0.44% greater reductions in HbA1c compared to patients in the control group at 3, 6, and 12 months, respectively (P &lt; 0.01). Patients managed by a CPP were also more likely to achieve the identified HbA1c targets of &lt;7% and &lt;8%.

Conclusion
Patients referred to a CPP were more complex, but had greater reductions in HbA1c and were more likely to achieve HbA1c goals included in the organization’s quality measures. This study demonstrates the value of pharmacists in improving patient care and their role in supporting an organization’s achievement of value-based quality measures.
iACVP: markedly enhanced identification of anti-coronavirus peptides using a dataset-specific word2vec model
Authors: Kurata Hiroyuki , Tsukiyama Sho , Manavalan Balachandran 
Published: July 2022

Abstract
The COVID-19 pandemic caused several million deaths worldwide. Development of anti-coronavirus drugs is thus urgent. Unlike conventional non-peptide drugs, antiviral peptide drugs are highly specific, easy to synthesize and modify, and not highly susceptible to drug resistance. To reduce the time and expense involved in screening thousands of peptides and assaying their antiviral activity, computational predictors for identifying anti-coronavirus peptides (ACVPs) are needed. However, few experimentally verified ACVP samples are available, even though a relatively large number of antiviral peptides (AVPs) have been discovered. In this study, we attempted to predict ACVPs using an AVP dataset and a small collection of ACVPs. Using conventional features, a binary profile and a word-embedding word2vec (W2V), we systematically explored five different machine learning methods: Transformer, Convolutional Neural Network, bidirectional Long Short-Term Memory, Random Forest (RF) and Support Vector Machine. Via exhaustive searches, we found that the RF classifier with W2V consistently achieved better performance on different datasets. The two main controlling factors were: (i) the dataset-specific W2V dictionary was generated from the training and independent test datasets instead of the widely used general UniProt proteome and (ii) a systematic search was conducted and determined the optimal k-mer value in W2V, which provides greater discrimination between positive and negative samples. Therefore, our proposed method, named iACVP, consistently provides better prediction performance compared with existing state-of-the-art methods. To assist experimentalists in identifying putative ACVPs, we implemented our model as a web server accessible via the following link: http://kurata35.bio.kyutech.ac.jp/iACVP.
Hand-Wing Index as a surrogate for dispersal ability: the case of the Emberizoidea (Aves: Passeriformes) radiation
Authors: Arango Axel , Pinto-Ledezma Jesús , Rojas-Soto Octavio , Lindsay Andrea M , Mendenhall Chase D , Villalobos Fabricio 
Published: July 2022

AbstractMeasuring the dispersal ability of birds is particularly challenging and thus researchers have relied on the extended use of morphological proxies as surrogates for such ability. However, few studies have tested the relationship between morphological proxies and other dispersal-related traits. In this study, we test the relationship of the most commonly used morphological proxy for dispersal—the Hand-Wing Index (HWI)—with traits highly associated with dispersal abilities, such as geographic range size, migratory behaviour and migratory distances. We used the Emberizoidea superfamily to evaluate these relationships and measured the HWI of 2520 individuals from 431 species (almost half of all the species in the superfamily). We first estimated the phylogenetic signal of HWI and searched for the best evolutionary model to explain its variation. We then performed PGLS analyses to assess the relationships between HWI and dispersal abilities. Our results showed that HWI has a strong phylogenetic signal and is positively related to dispersal abilities. Our findings support the use of HWI as a viable morphological proxy for dispersal in birds.
G protein-coupled estrogen receptor promotes acrosome reaction via regulation of Ca2+ signaling in mouse sperm
Authors: Gao Dong-Dong , Lan Chong-Feng , Cao Xiao-Nian , Chen Lei , Lei Tian-Lun , Peng Lei , Xu Jia-Wen , Qiu Zhuo-Er , Wang Long-Long , Sun Qing , Huang Zi-Yang , Zhu Yun-Xin , Zhou Wen-Liang , Zhang Yi-Lin 
Published: July 2022

Abstract
G protein-coupled estrogen receptor (GPER), a seven-transmembrane G protein-coupled receptor, mediates the rapid pre-genomic signaling actions of estrogen and derivatives thereof. The expression of GPER is extensive in mammal male reproductive system. However, the functional role of GPER in mouse sperm has not yet been well recognized. This study revealed that GPER was expressed at the acrosome and the mid-flagellum of the mouse sperm. The endogenous GPER ligand 17β-estradiol and the selective GPER agonist G1 increased intracellular Ca2+ concentration ([Ca2+]i) in mouse sperm, which could be abolished by G15, an antagonist of GPER. In addition, the G1-stimulated Ca2+ response was attenuated by interference with the phospholipase C (PLC) signaling pathways or by blocking the cation channel of sperm (CatSper). Chlortetracycline staining assay showed that the activation of GPER increased the incidence of acrosome-reacted sperm. Conclusively, GPER was located at the acrosome and mid-flagellum of the mouse sperm. Activation of GPER triggered the elevation of [Ca2+]i through PLC-dependent Ca2+ mobilization and CatSper-mediated Ca2+ influx, which promoted the acrosome reaction of mouse sperm.
Gestational diabetes mellitus suppresses fetal testis development in mice
Authors: Mo Jia-Ying , Yan Yi-Shang , Lin Zhong-Liang , Liu Rui , Liu Xuan-Qi , Wu Hai-Yan , Yu Jia-En , Huang Yu-Tong , Sheng Jian-Zhong , Huang He-Feng 
Published: July 2022

Abstract
The prevalence of gestational diabetes mellitus (GDM) is increasing rapidly. In addition to the metabolic disease risks, GDM might increase the risks of cryptorchidism in children. However, its mechanism involved in abnormalities of the male reproductive system is still unclear. The purpose of this study was to study the effects of GDM on the development of mouse fetal Leydig cells (FLCs) and Sertoli cells (SCs). Pregnant mice were treated on gestational days 6.5 and 12.5 with streptozotocin (100 mg/kg) or vehicle (sodium citrate buffer). Leydig cell and SC development and functions were evaluated by investigating serum testosterone levels, cell number and distribution, genes, and protein expression. GDM decreased serum testosterone levels, the anogenital distance, and the level of desert hedgehog in SCs of testes of male offspring. FLC number was also decreased in testes of GDM offspring by delaying the commitment of stem Leydig cells into the Leydig cell lineage. RNA-seq showed that FOXL2, RSPO1/β-catenin signaling was activated and Gsk3β signaling was inhibited in GDM offspring testis. In conclusion, GDM disrupted reproductive tract and testis development in mouse male offspring via altering genes related to development.