bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of mode of delivery on parent-infant-bonding and the mediating role of birth experience: A comparison of mothers and fathers within the longitudinal cohort study DREAM
Authors: Döblin Svenja , Seefeld Lara , Weise Victoria , Kopp Marie , Knappe Susanne , Asselmann Eva , Martini Julia , Garthus-Niegel Susan 
Published: August 2022

Abstract
Background
The association between mode of delivery (MOD) and parent-infant-bonding has only been studied in mothers and findings have been inconclusive. The aim of this study was to prospectively investigate how MOD relates to postpartum parent-infant-bonding in both mothers and fathers and whether these associations are mediated by birth experience.
Methods
This study is part of the prospective cohort study “Dresden Study on Parenting, Work, and Mental Health” (DREAM). Our sample comprised N = 1,780 participants who completed quantitative questionnaires during pregnancy as well as 8 weeks and 14 months postpartum. MOD was dummy coded, contrasting spontaneous vaginal delivery against vaginal delivery induced by drugs, operative vaginal delivery, planned, and unplanned cesarean section. Parent-infant bonding and birth experience were assessed using validated scales. A moderated mediation analysis based on ordinary least square (OLS) regression and bootstrapped estimates was conducted, considering relevant confounding variables.
Results
Compared to spontaneous vaginal delivery, all categories of MOD predicted more negative birth experiences in both parents. A more positive birth experience predicted stronger parent-infant-bonding at 8 weeks, but not at 14 months postpartum. Mothers who delivered via cesarean section (planned or unplanned) reported stronger parent-infant-bonding at 8 weeks and 14 months postpartum. In fathers, only unplanned cesarean section was associated with stronger parent-infant-bonding at 8 weeks postpartum. At 8 weeks postpartum, birth experience mediated the association between a vaginal delivery induced by drugs and a planned cesarean section and mother-infant-bonding and between a vaginal delivery induced by drugs, an operative vaginal delivery, and planned cesarean section and father-infant-bonding. At 14 months postpartum, birth experience mediated the association between a vaginal delivery induced by drugs, operative vaginal delivery, and planned cesarean section and parent-infant-bonding in both parents.
Conclusions
The results emphasize the importance of the birth experience for parent-infant-bonding in both mothers and fathers. Further research should address the mechanisms by which parents with an unplanned cesarean section establish stronger parent-infant-bonding compared to parents whose baby was delivered via spontaneous vaginal delivery, despite their overall more negative birth experiences.
Clinical features and relapse risks factors of immunoglobulin G4–related disease: a single-center retrospective study
Authors: Zhang Xinhe , Zeng Zilu , Tian Haoyu , Wang Ningning , Wang Ying , Tong Jing , Chang Bing , Jin Xiuli , Huang Die , Wang Yanmeng , Cui Huipeng , Guan Lin , Li Yiling 
Published: August 2022

Abstract
Objective: The aim of this study was to observe the demographic and clinical characteristics of immunoglobulin (Ig) G4–related disease (IgG4-RD). We aimed to compare different treatment methods and to identify the risk factors for non-response and relapse after treatment.Methods: We performed a retrospective study of 201 IgG4-RD patients initially diagnosed and treated at the First Affiliated Hospital of China Medical University from January 2016 to December 2020. Patients’ sex, age, clinical manifestations, baseline biochemical values, the number of organs involved, and the type of organ involvement were recorded. All patients received glucocorticoid (GC) monotherapy or GC + immunosuppressant combination therapy. The serum IgG4 concentration as well as the details of clinical response, relapse, and side effects were recorded at 1, 3, 6, and 12 months after treatment.Results: The incidence of IgG4-RD was primarily centered in the age group of 50–70 years old, and the proportion of affected male patients increased with age. The most common clinical symptom was swollen glands or eyes (42.79%). The rates of single- and double-organ involvement were 34.83% and 46.27%, respectively. The pancreas (45.77%) was the most frequently involved organ in cases of single-organ involvement, and the pancreas and biliary tract (45.12%) was the most common organ combination in cases of double-organ involvement. Correlation analysis showed that the number of organs involved was positively related to the serum IgG4 concentration (r = 0.161). The effective rate of GC monotherapy was 91.82%, the recurrence rate was 31.46%, and the incidence of adverse reactions was 36.77%. Meanwhile, the effective rate of GC + immunosuppressant combination therapy was 88.52%, the recurrence rate was 19.61%, and the adverse reaction rate was 41.00%. There were no statistically significant differences in response, recurrence, and adverse reactions. The overall response rate within 12 months was 90.64%. Age (<50 years old) and aorta involvement were significantly associated with non-response. The overall recurrence rate within 12 months was 26.90%. Age (<50 years old), low serum C4 concentration, a high number of involved organs, and lymph node involvement were significantly associated with recurrence.Conclusion: The clinical features vary among different age groups and according to gender. The number of organs involved in IgG4-RD is related to the serum IgG4 concentration. Age (<50 years old), low serum C4 concentration, a high number of involved organs, and lymph node involvement are risk factors for recurrence.
Technique and clinical results of a new intramedullary support nail and plate system for fixation of 3- or 4- part proximal humeral fractures in older adults
Authors: Bai Xuedong , Zhu Zhengguo , Chang Zuhao , Sun Lijun , Tang Peifu , Chen Hua 
Published: August 2022

Abstract
Background: Internal fixation of complex proximal humeral fractures (PHF) with osteoporosis is associated with a high incidence of complications. This study introduces the technique and clinical results of a novel intramedullary support nail and plate system (ISNPs) for the internal fixation of 3- or 4- part PHF in older adults. The ISNPs combines the concept of intramedullary support and dynamic fixation into a locking plate fixation system that can be applied using a minimally invasive surgical approach.Methods: A total of 46 consecutive patients diagnosed with 3- or 4-part PHF that met the criteria were included in this study, including 18 in the ISNPs group and 28 in the conventional locking plate (LP) group. Clinical results, including operative time, intraoperative bleeding, reduction quality, subjective outcome ratings, and complications, were compared between the two groups. Functional outcomes were evaluated using the Constant score and disability of the arm, shoulder, and hand (DASH) questionnaire at 1-year follow-up.Results: There were no significant differences in age, sex, local bone quality, Neer-fracture type, and follow-up time between the ISNPs and LP groups. For clinical analysis, there were no significant differences in intraoperative bleeding and operation time between the ISNPs and LP groups. Significant differences were observed in the percentage of the malreduced cases, Constant and DASH score analysis, and “excellent” and “good” ratings between the two groups. Conclusion: The ISNPs technique proposed in this study provides a novel hybrid internal fixation model for complex PHF with osteoporosis. The clinical results at 1-year follow-up confirmed the advantage of applying it to 3- or 4- part PHF in older patients. Further studies are required to optimize its design and explore its optimal indications.
Synergistic effect of combined treatment with allicin and antioxidants of bamboo leaves and preservation of bullfrog (Lithobates catesbeiana) during refrigeration storage
Authors: DU Jintao , LAN Weiqing , ZHU Shengyun , XU Xiao , XIE Jing 
Published: August 2022

Abstract
The effects of allicin (All) and antioxidant of bamboo leave (AOB) on the quality of bullfrog (Lithobates catesbeiana) during refrigerated storage were investigated. The results demonstrated that the treatment of All and AOB could reduce the decline of moisture loss and maintain the water-holding capacity (WHC). In addition, combination treatment inhibited the increase of total viable counts (TVC), exhibited good antibacterial activity, delayed the decrease of amino acid content and retarded the sensory deterioration. The reduction of thiobarbituric acid (TBA) and total volatile basic nitrogen (TVB-N) indicated that allicin combined with antioxidant of bamboo leave (AA) could restrain the degradation of protein and lipid oxidation. As a consequence, AA treatment prolonged the shelf-life of bullfrogs for another 6 days. Allicin combined with antioxidant of bamboo leave treatment could be an effective approach to extend the shelf-life and delay the biochemical reaction of refrigerated bullfrog.
Assessment of different experimental setups to determine viral filtration efficiency of face masks
Authors: Filipić Arijana , Fric Katja , Ravnikar Maja , Kogovšek Polona 
Published: August 2022

Abstract
As a result of the pandemic COVID -19 many new materials and masks came on the market. To determine their suitability, several standards specify which properties to test, including bacterial filtration efficiency (BFE), while none describe how to determine viral filtration efficiency (VFE), a property that is particularly important in times of pandemic. Therefore, we focused our research on evaluating the suitability and efficiency of different systems for determining VFE. Here, we evaluated the VFE of 6 mask types (e.g., a surgical mask, a respirator, material for mask production and cloth masks) with different filtration efficiencies in four experimental setups and compared the results with BFE results. The study included 17 BFE and 22 VFE experiments with 73 and 81 mask samples tested, respectively, making it one of the most comprehensive studies in the field. We have shown that the masks tested had high VFE (>99% for surgical masks and respirators, ≥98% for a material and 87-97% for cloth masks) and that all experimental setups provided highly reproducible and reliable VFE results (coefficient of variation < 6%). Therefore, the VFE tests described in this study can be integrated into existing standards for mask testing.
Pilot-scale production of highly durable bioactive and UV-protective cotton fabric by electroless deposition of copper on cotton fabric
Authors: Nosheen Anum , Khalid Madiha , Manzoor Sobia , Ashraf Munir , Xue Zhebin , Khan Daniyal Sajid , Urooj Sidra , Hashmi Asraf Hussain 
Published: August 2022

Abstract
Surface metallization of textiles through electroless deposition to develop multifunctional textiles has become an active area of research lately. However, little attention has been paid on the development of durable bioactive textiles as well as the scalability of electroless deposition process. In the current study, the pilot-scale production of highly durable bioactive textiles through electroless deposition of copper on cotton fabric has been achieved. For this, the surface of cotton fabric was first sensitized with stannous chloride (SnCl2) followed by activation with silver nitrate (AgNO3) solution. Then, the electroless deposition of copper was achieved on sensitized and activated cotton fabric. FTIR, SEM, EDS, and ICP-OES spectroscopic techniques were employed to validate the successful development of electroless plated copper fabric. The antimicrobial potential of developed fabric (before and after 30 industrial washes) towards bacteria (S. aureus and E. coli), virus (dengue virus) and fungi (A. Niger) was also evaluated. The prepared samples exhibited remarkable antimicrobial potential with excellent washing durability. The antimicrobial activity was retained with the same effectiveness even after 30 industrial washings (more than 100 home launderings). Moreover, the developed samples showed excellent protection against harmful UV-radiations i.e., + 50 UPF. The current research has established a facile, cost-effective, non-toxic, and scalable process for the production of exceptionally durable bioactive textiles and it can be easily implemented at industrial scale.
Factors Associated with The Speed and Scope of Diffusion of COVID-19 Therapeutics in a Nationwide Healthcare Setting: A Mixed Methods Investigation
Authors: La Jennifer , Fillmore Nathan , Do Nhan , Brophy Mary , Monach Paul , Branch-Elliman Westyn 
Published: August 2022

Abstract
Limited empiric data are available regarding factors associated with rapid dissemination and diffusion in healthcare. The aim of this study was to identify factors associated with the speed and scope of uptake of novel COVID-19 therapeutics. Adoption of first-in-class therapeutics occurred rapidly and was sustained, after press releases, coverage by traditional and social media outlets, and pre-prints, and prior to peer-reviewed publication and guideline updates. High-quality evidence generated and published during later periods in the pandemic had a slower rise and lower peak uptake, indicating practice change is harder after a clinical niche is perceived to be filled. The Speed and Scope of Diffusion Matrix created and presented could be tested and applied in other settings to predict the speed and spread of novel therapeutics.
Household food insecurity and its association with childhood overweight and obesity
Authors: Ortiz-Marrón Honorato , Ortiz-Pinto Maira Alejandra , Lanza María Urtasun , Pujadas Gloria Cabañas , Pino Virginia Valero , Cortés Susana Belmonte , Gascón Tomás Gómez , Gavín María Ordobás 
Published: August 2022

Abstract
Background. The objective was to estimate the prevalence of household food insecurity (HFI), associated sociodemographic factors and their relationship with childhood overweight and obesity.Methods. The data come from 1,938 children aged 2 to 14 years who participated in the Malnutrition Study of the Community of Madrid. Weight and height were obtained through physical examination. Body mass index was calculated as weight in kilograms divided by height in meters squared, and for the definition of overweight and obesity, the criteria of the World Health Organization (WHO) were used. The parents of the participants answered a structured questionnaire about the diet, lifestyle (physical activity and use of TV and computer screens) and food insecurity. The diet quality was assessed by the Healthy Eating Index (HEI) in Spain. The HFI was evaluated with the Household Food Insecurity Access (HFIAS) survey. Odds Ratios (ORs) and Relative Risk Ratios (RRRs) were estimated using logistic regression models adjusted for confounding variables.Results. The prevalence of HFI was 7.7% (95% CI: 6.6-9.0). The prevalence was lower in children 2 to 4 years (5.7%, 95% CI: 4.0-8.1) and higher in households with low family purchasing power (37.3%; OR: 8.99 (95% CI: 5.5-14.6). Children who were at HFI had a lower diet quality and spent more time in front of screens, and had a higher prevalence of overweight (33.1%) and obesity (28.4%) than those who lived in household food security (HFS) (21.0% and 11.5%, respectively). Compared with children in HFS, those who lived in HFI had RRRs of overweight of 2.41 (95% CI: 1.5-4.0) and 1.99 (95% CI: 1.2-3.4) of obesity.Conclusions. HFI reaches a high prevalence among children, especially in households with low family purchasing power. HFI probably is associated with lower diet quality and an increase in the prevalence of childhood overweight and obesity. Our results suggest the need to detect early, in paediatric services, at-risk households to avoid this double burden of child malnutrition.
Effectiveness of ACI-318 and TS-500 Codes on Nonlinear Seismic Analysis of RC structures: Force-Based Approach
Authors: KARATON MUHAMMET , OSMANLI Ömer Faruk , AWLA Halmat Ahmed 
Published: August 2022

Abstract

Different equations for the material properties of concrete are suggested in several national codes. The effectiveness of these equations on the nonlinear seismic analysis of RC structures for the material properties has been an important research subject. In this study, the effectiveness of ACI-318 and TS 500 design codes is investigated in the numerical modeling of RC structures. For this purpose, the seismic responses of two RC structures experimented in the laboratory are used. The first structure is a two-dimensional three-bay and four-story RC bare frame structure that was tested in European Laboratory for Structural Assessment. The second structure is an RC tall bridge pier that was tested at Pacific Earthquake Engineering Research Center. The numerical solutions are obtained by using the Force-based Fiber Element Approach. The experimental and numerical analysis results are compared in terms of top displacements and damage zones. The concrete material properties which provide the best approximation to the experimental results are investigated for both design codes. It is concluded that the material properties of RC structures determined according to the ACI-318 code can be used for the Force-based Fiber Element Approach with regard to displacement response and damage regions.
Digital map and probability compensation model for repeated positioning error of feed axis
Authors: Wu Huayang , Zuo Dunwen 
Published: August 2022

Abstract
The randomness of the repeated positioning error of feed shaft is the main reason for the difficulty to address this error. The previous repeated loading and unloading suppression methods will easily do damages to parts. This paper sets out to investigate the probability distribution of all possible error values while feed shaft is at different positions, and determine the maximum value of probability error from the random errors. With feed axis at a certain position, first of all, we count the probability of each error based on a large number of random errors. We also draw the digital map of the repeated positioning error of this error with the error of positive and negative stroke measurement as the x-axis and y-axis coordinates and the probability of each error value as the z-axis coordinates Secondly, based on the digital map of each position on the feed axis and combined with the dynamic optimization algorithm, we find the highest point on the map and take the coordinate point of this point as the starting point of each position compensation. Then, we set the error probability threshold to control the possibility of compensation errors and output the size and direction of the final compensation value. Finally, we start the compensation command and detect the compensated error. The error data that fail to meet the requirements will enter the probability statistics again, redraw the digital map and update the map. Through real-time detection and feedback, the digital map is dynamically improved to adapt to the changing environment. This probability compensation model of repeated positioning error can end the suppressing repeated positioning errors brought by repeatedly disassembling parts.
High mean platelet volume is associated with cerebral white matter hyperintensities in non-stroke individuals
Authors: Choi Jung-Won , Lee Kee Ook , Jang Ye-Ji , Kim Hyun-Kyung , Seo TaeHo , Roh Yoo Jeong , Choo Seung-Ook , Oh Seung-Hun 
Published: August 2022

Abstract
Background: Mean platelet volume (MPV) is regarded as a marker for thrombosis, atherosclerosis, and inflammation in various vascular diseases including stroke. However, it is still unclear whether plasma MPV is associated with cerebral white matter hyperintensities (WMH) and cerebral microvascular pathology in the elderly. Methods: We examined whether MPV level is associated with the presence of cerebral WMH on brain magnetic resonance imaging (MRI) from 870 non-stroke outpatient subjects. The subjects were divided into three groups according to the consecutive level of MPV (low T1, middle T2, and high T3 MPV tertile groups). Demographic data and laboratory data for vascular risk factors were evaluated.Results: Univariate analysis disclosed that old age, hypertension, diabetes mellitus, and low renal function were more prevalent in subjects with higher MPV level. In addition, cerebral WMH were more prevalent in subjects with higher MPV level. After adjusting confounding factors, moderate to severe cerebral WMH were significantly associated with high MPV tertile level. This association remained significant after adjusting for other cerebral vascular pathologies such as large artery atherosclerosis of cerebral arteries, displaying that subjects with middle MPV level (odds ratio (OR): 1.49, 95% confidence interval (95%CI): 1.03-2.15) and those with high MPV level (OR: 1.51, 95%CI: 1.04-2.20) had cerebral WMH lesions more than those with low MPV level. Subjects with more severe cerebral WMH had higher plasma MPV levels than those without (p = 0.02). Conclusions: We found that high MPV level is independently associated with cerebral WMH. This result suggests that platelet activation plays a role in the development of cerebral WMH.
Bioinformatics analysis of long non-coding RNA-associated competing endogenous RNA network in hepatoblastoma
Authors: Ranjbari Haidar , Tezerjani Masoud Dehghan , Sabaghi Fatemeh , Dibaj Mohsen , Jalil Abduladheem Turki , Kadhim Mustafa M. , Shams Zinat , Karimi Zeinab 
Published: August 2022

Abstract
Hepatoblastoma (HB) is a common pediatric hepatic tumor. Occurrence and progression of various malignancies are enhanced by abnormal competitive endogenous RNA (ceRNA) axes. Although, ceRNAs can be considered effective prognostic, diagnostic, and therapeutic targets, it is poorly investigated in HB. An lncRNA-related ceRNA network is developed in the current study to clarify HB's underlying molecular regulatory mechanism. First, two microarray datasets regarding the liver specimens of HB patients and controls were downloaded from Gene Expression Omnibus database, which contained mRNAs, lncRNAs (GSE75271), and miRNAs (GSE75283) data. R software package limma was used to identify the differentially expressed lncRNAs (DElncRNAs), mRNAs (DEmRNAs), and miRNAs (DEmiRNAs). Databases, miRTarBase and DIANA-LncBas, were applied to identify RNA interactions. The enrichment of pathways for DEmRNAs was done by Enrich tool. Cytoscape and STRING were utilized for the development of a protein-protein interaction network of DEmRNAs and the identification of the top five hub genes. Eventually, based on DElncRNA-miRNA-DEmRNA connections and co-expressions, the lncRNA-associated ceRNA axes were constructed. Results of the present study showed that 39 DEmRNAs (e.g., CDK4, CDK6, CCNA2, CCND2, and HMGA2) are involved in the HB ceRNA network. Furthermore, 27 DElncRNAs (e.g., CRNDE, GAS5, LINC00205, and ZFAS1) were identified as regulating the mentioned mRNAs through sponging eight DEmiRNAs (e.g., hsa-miR-195-5p, hsa-miR-29c-3p, hsa-miR-22-3p, hsa-let-7c-5p, hsa-let-7g-5p). Analysis of pathway enrichment demonstrated the enrichment of DEmRNAs in "Pathways in cancer", "MicroRNAs in cancer", "Hippo signaling pathway", "Human papillomavirus infection", and "Cellular senescence". This study identified the ceRNAs networks important for the molecular mechanism of HB development.