bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexual dimorphism in the response to dietary restriction in mice: A systematic review of the literature
Authors: Mitchell Sarah J. , Mitchell James R. 
Published: September 2022

Background: Dietary restriction (DR) is a widely used experimental intervention in aging research due to its consistent ability to extend lifespan in most species tested. DR is an all-encompassing term describing interventions that restrict some aspect of nutrition - from calorie amount to calorie type to timing of food intake - and yet share common functional endpoints including extended longevity, but also improvements in healthspan, or the time spent in good health, as well as metabolic fitness and stress resistance. Recent studies highlight the preponderance of sexual dimorphisms in the response to DR and argue for the importance of inclusion of both sexes in preclinical research. OBJECTIVE: We set out to perform a comprehensive assessment of documented health and lifespan outcomes of interventional DR studies in mice that display sexual dimorphism. METHODS: A systematic literature search was conducted according to the PRISMA statement to identify mouse DR studies in which both sexes were included using PubMed. The specific DR interventions examined included calorie restriction (CR), intermittent fasting (IF), protein restriction (PR) and methionine restriction (MetR), with experimental endpoints focused on lifespan and healthspan. RESULTS: Sexual dimorphism in the lifespan and healthspan effects of various DR regimens is a common finding in mice, with the magnitude and direction of dimorphic responses influenced by the specific dietary intervention as well as the strain of mouse used in the study. CONCLUSIONS: Despite the fact that preclinical lifespan and healthspan analyses in mice reveal sexual dimorphism in the response to DR, there is still a large gap in our understanding of how sex affects dietary outcomes. More preclinical research comparing both sexes in the same study with better attention to reporting metrics during peer review and in easily searchable text including title and abstract is required to further our understanding of the impact of sex on health and lifespan in response to DR in rodent studies.
Communication information exchange and transmission method of industrial Internet of things based on audio information hiding
Authors: Tian Yinlei , Wang Haiyan 
Published: September 2022

In order to improve the accuracy of information exchange transmission and reduce the transmission response delay, this paper proposes an industrial Internet of things communication information exchange transmission method based on audio information hiding. Firstly, information embedding algorithm is used to extract the communication audio carrier information. Secondly, audio information hiding algorithm is used to realize the hidden embedding of specific information; Then, the information transmission data integration is realized according to the similarity matrix. Finally, the Pareto distribution is used to realize the information transmission data matching, and the audio information hiding is used to realize the data exchange transmission control. The experimental results show that the transmission accuracy of this method is 98.3%, the transmission accuracy is as high as 96.0%, and the response delay is only 16 ms, indicating that this method can improve the transmission effect of industrial Internet of things communication information exchange.
ERA UMA VEZ NO HOSPITAL
Authors: Pessini Marcia 
Published: September 2022

O Projeto de Extensão - Era Uma Vez no Hospital - tem como objetivo levar a contação de histórias para crianças em hospitais e outras instituições de Foz do Iguaçu. Pretende-se aqui apresentar um histórico do desenvolvimento desse projeto, que teve início no ano de 2012 e desde o início da pandemia teve que sofrer drásticas alterações. O projeto ocorre a partir da organização e realização de visitas periódicas ao Hospital Ministro Costa Cavalcanti, quando são feitas contações de histórias para as crianças internadas na ala da oncologia infantil. Nessas visitas, o grupo formado pela coordenadora do projeto e seus alunos voluntários e/ou bolsistas do IFPR, contavam histórias infantis às crianças, utilizando diferentes materiais e recursos. Os mesmos eram preparados e/ou confeccionados com antecedência pelo grupo e as visitas eram previamente programadas junto à enfermeira responsável pelo setor. O projeto é muito salutar para crianças hospitalizadas, mas os maiores beneficiados com esse projeto são os alunos do IFPR que tem a oportunidade de terem o melhor dos públicos e ainda conhecer a magia de conquistar o sorriso em uma criança.
Examining the influence of treatment preferences on attrition, adherence and outcomes: a protocol for a two-stage
partially randomized trial
Authors: Sidani Souraya , Fox Mary , Streiner David L. , Miranda Joyal , Fredericks Suzanne , Epstein Dana R. 
Published: September 2022

<p>Background: Empirical evidence pertaining to the influence of treatment preferences on attrition, adherence and outcomes in intervention evaluation trials is inconsistent. The inconsistency can be explained by the method used for allocating treatment and measuring preferences. The current methodological study is designed to address these factors by implementing the two-stage partially randomized or preference trial design, and administering a validated measure to assess participants’ preferences for the treatments under evaluation. It aims to compare attrition, adherence and outcomes for participants allocated randomly or by preference to treatment. The study is in its final stages of data collection; its protocol is presented in this paper. </p>
<p>Methods/Design: A partially randomized clinical or preference trial is used. Eligible participants are randomized to two trial arms. First is the random arm involving random assignment to treatments, and second is the preference arm involving allocation to the chosen treatment. Participants with chronic insomnia are targeted. Two behavioral treatments are offered, stimulus control therapy and sleep restriction therapy, in the same format (small group) and dose (two sessions given over a 4-week period). A participant log is used to collect data on attrition. Adherence is evaluated in terms of exposure and enactment of treatment. Sleep-related outcomes (sleep parameters and perceived insomnia severity) are measured at pretest, posttest, 6 and 12 month follow-up. Treatment preferences, adherence and outcomes are assessed with reliable and valid measures. </p>
<p>Discussion: The advantages and limitations of the preference trial design are highlighted. The challenges in implementing the trial are discussed relative to the distribution of participants in the groups defined by treatment received and method of treatment allocation. </p>
<p>Trial registration: ClinicalTrials.gov Registry NCT02513017</p>
Exploring Commuting for Work in Kuala Lumpur
Authors: Mohd Zahari Haliza , Azhar Nur Hidayah , Ismail Ariffin , Baker Rogis , Mohd Saudi Nur Surayya 
Published: September 2022

Many workers face challenges in suburban areas when commuting to the urban areas from home to work. Public transportation is a fundamental component of efficient transportation in urban areas. Efficient transportation will increase economic opportunity, accessibility, and social development. This paper explored the characteristics of commuting behavior of the workers in the Klang Valley who commute to work in Kuala Lumpur, including their choice of transportation modes and the challenges they faced in traveling from home to work. This study engaged a mixed methodology where data were collected from 709 respondents voluntarily. The survey was initiated in December 2020 and lasted for six months. The respondents were approached through voluntary face-to-face and electronic means. Interviews were conducted with 14 key informants in April 2021 with workers from various backgrounds who commute to work every day. The interviews were done one-on-one. The result showed that the likelihood of choosing public transport over driving privately owned car was unfavorable where most individuals stated that the public transportation was insufficient; they had to take more than one modes to reach their workplace, and the facilities provided were insufficient for them to choose public transportation for commuting to work. These results shown that the urban workers in Kuala Lumpur preferred to drive to work rather than using public vehicles. This shows that Malaysians, especially in urban areas such as Kuala Lumpur, are not ready to adapt to SDG 11. Therefore, the government needs to create more initiatives to encourage the use of public transport.
Social Condition of French Society pre-revolution in A Tale of Two Cities Novel by Charles Dickens
Authors: Syawal La Ode Muhamad Irwin , Rahman Fathu , P. M. Amir 
Published: September 2022

Penelitian ini bertujuan untuk menganalisis permasalahan kondisi sosial masyarakat Prancis sebelum potret revolusi dalam novel A Tale of Two Cities karya Charles Dickens. Keterkaitan karya sastra sebagai penggambaran kehidupan sosial membuktikan bahwa karya sastra selalu memiliki keberpihakan. Oleh karena itu, dapat dikatakan bahwa karya sastra merupakan karya tendensius yang berarti memiliki tujuan tertentu di balik penciptaannya. Penelitian ini menggunakan pendekatan kualitatif dan sosiologi sastra. Hasil penelitian menunjukkan bahwa kondisi sosial masyarakat Perancis dimana rakyatnya hidup dalam kemiskinan dan rakyat miskin dieksploitasi oleh kaum bangsawan, kelaparan melanda di setiap sudut kota, kakunya hukum pada masa sistem monarki, dan penyalahgunaan kekuasaan oleh kaum bangsawan kepada orang-orang miskin, yang menjurus pada revolusi yang dipimpin oleh orang-orang miskin. Peneliti menyimpulkan bahwa kondisi sosial masyarakat sebelum revolusi adalah kemiskinan, kelaparan, hukum yang kaku, dan penyalahgunaan kekuasaanThis research aims to analyze the problem of social condition of French society before the revolution portrait in A Tale of Two Cities novel written by Charles Dickens. The linkage of literary works as a portray of a social life proves that a literary work always has partiality. Therefore, it can be said that literary work is a tendentious work which means having certain purposes behind its creation. This research uses the qualitative and sociology of literature approach. The result of the research that the social condition of French society where the people live in poverty where the poor people exploited by the noble, famine struck in every corner of the city, rigid of law during the monarchy system, and power abuse by the nobles to the poor people, which lead this into revolution lead by the poor people. The Researcher concluded that social condition of the society before the revolution are poverty, famine, rigid law, and power abuse.Keywords: Sociology of Literature, Social Condition, Revolution.
Hostility in Philosophy – ­Between Hegel and Heidegger
Authors: Lindberg Susanna 
Published: September 2022

The starting point of this chapter is Derrida's reading of Aristotle's idea of friendship that is at the same time a necessary and impossible condition of philosophy. I will test Derrida's idea in a specific case, that of the "friendship" between Hegel and Heidegger, between whom, as I will show, "there is not friendship" at all, but an active hostility (that I will also refer to Derrida's discussion of Schmitt). However, instead of regarding hostility as an obstacle to dialogical philosophy, I will show how it grows into a condition of radically open philosophizing. Finally, this reading also functions as a deconstruction of Heidegger's conception of love of truth that Derrida presents in the last part of Politiques de l'amitié, Philopolémologie.
Responding Justly to ‘the Friend’
Authors: Cohen Joseph , Zagury-Orly Raphael 
Published: September 2022

The essay “Heidegger’s Ear. Philopolemology (Geschlecht IV)”, although omitted in the English language edition of the Politics of Friendship, figures as the last chapter in its original French edition (Paris, Galilée, 1994). In this text, Jacques Derrida analyses Heidegger’s interpretation of Heraclitus, most particularly the meaning of the Heraclitean polemos, through which the former proposes an entirely novel reading of the “als Hören der Stimme des Freundes, den jedes Dasein bei sich trägt” in Sein und Zeit (§ 34, p. 163).
In our contribution, we will develop a succinct explication of Derrida’s text and mark how it deploys, in relation to the general hypothesis of the Politics of Friendship, a resounding deconstructive critique of Heidegger’s ontological-philosophical project as a whole as well as offer a renewed approach of the intricate relation between the political and friendship. We will also develop how and why this relation intervenes and affects the hyperbolical and “indeconstructible” idea of justice which Derrida, in the same years as the Politics of Friendship, is explicating and deploying in other key texts, such as Force of Law (Paris, Galilée, 1994).
The Law of Autoimmunity
Authors: Lloyd Chris 
Published: September 2022

Lloyd's chapter, 'The Law of Autoimmunity,' argues that The Politics of Friendship should be recognised as the text which features the inaugural appearance of Jacques Derrida's last great master-concept: autoimmunity. The chapter illustrates three, originary, appearances of autoimmunity: two explicit, as per Derrida’s original French text, and one implicit, ex post facto, as per Derrida’s own re-reading of The Politics of Friendship, some fifteen years later. The chapter also argues that although some commentators have concentrated on reading autoimmunity’s immunological-biological connotations, this is in fact an error, contradicting Derrida’s own clarifications on his usage of autoimmunity. By way of correction, the chapter argues that autoimmunity is best understood as a juridico-political concept, first appearing in one of Derrida’s most famously political texts. Finally, the chapter argues that Derrida had begun to propose a cohesive, general, ‘law’ of autoimmunity, emanating from his deconstructive thought.
Modal Aporias: Derrida on the reale Möglichkeit of Friends and Enemies in Schmitt
Authors: Collison Luke 
Published: September 2022

Derrida’s engagement with Carl Schmitt, in Politics of Friendship, pursues multiple, intertwined deconstructive strategies. This chapter retraces the lines of approach made through the modal category “real possibility”, a modality that appears to lie in the space of spectrality, between the usual categories of possibility and actuality. Elaborating Derrida’s attempted “spectral inversion” of Schmitt’s friend/enemy distinction, the chapter critiques a key moment in which Derrida equivocates between the exceptional and the improbable. Instead of the spectral, the chapter suggests that post-thermodynamic models of energy offer a better model for Schmitt’s use of the real possibility, based on his interest in Georges Sorel.
‘The price of our loyalty?’ Ulster Landlords, Tenants and the Northern Ireland Land Act of 1925
Authors: Purdue Olwen 
Published: September 2022

This chapter explores the particular relationship that existed between 'unbought' northern Protestant tenants and their landlords in Northern Ireland following partition and the creation of the new state. It examines the campaign for land reform, the progress of the Act, and its implications for landed estates in Northern Ireland. By exploring the responses to the Act among northern tenants, many of whom were Protestant unionists, it seeks to highlight the complexity of social, religious and economic relationships in the north of Ireland during the opening decades of the twentieth century.
Anti-Racism as Vocational Practice: Reading with Alice Walker, Chimamanda Ngozi Adichie and Edwidge Danticat
Authors: Hasler-Brooks Kerry 
Published: September 2022

Literary reading, used as vocation-building both individually and collectively, can enact antiracism. Focusing on significant voices within Black women’s writing, the chapter contends that reading can cultivate antiracist thinking and action, both through an examination of the writer’s personal experience and through textual analysis. Reading calls us to reimagine a world held captive by racism. In personal essays that are simultaneously aesthetic treatises, literacy narratives, and vocation memoirs, Alice Walker, Chimamanda Ngozi Adichie, and Edwidge Danticat tell and retell their reading stories. Three modes of reading shape these writers’ vocational ethics and, by extension, the vocation-building of their readers: reading as intertextual reflection, reading as social transformation, and reading as global connection. This chapter casts the imaginative work of reading as means to do the vocational work of restoring and remaking the world around us—even a world that privileges white identity and that denies black women in particular a voice.
Translating Vocation
Authors: Paden Jeremy 
Published: September 2022

For students of literature-in-translation, the linguistic and cultural nuances that are lost may also be generative places for discovery and transformation. As translators, we emphasize the importance of cultural difference and literary study to broader audiences, expanding the ways we read literature, language and the concept of vocation itself. The challenge of finding a shared vocabulary to speak about vocation can be understood as a problem of translation. Recognizing the richness of difference allows for an expansive lens through which to see how the study of literature in translation and the theory of translation can prompt self-reflection and awareness. This chapter considers vocational discernment through the teaching of literature in translation—primarily Don Quixote and Latin American philosophy—and in doing so addresses the problematic notion of ‘world literature’ as well as the issues presented by variances in national/linguistic traditions. Approaching vocation through the lens of translation illumines the necessity of deep listening to the particularities of self and other. Both stress the importance of context, the need for cultural awareness, respect for the other, and intellectual humility.
Artificial intelligence in civil infrastructure health monitoring—Historical perspectives, current trends, and future visions
Authors: Mondal Tarutal Ghosh , Chen Genda 
Published: September 2022

Over the past 2 decades, the use of artificial intelligence (AI) has exponentially increased toward complete automation of structural inspection and assessment tasks. This trend will continue to rise in image processing as unmanned aerial systems (UAS) and the internet of things (IoT) markets are expected to expand at a compound annual growth rate of 57.5% and 26%, respectively, from 2021 to 2028. This paper aims to catalog the milestone development work, summarize the current research trends, and envision a few future research directions in the innovative application of AI in civil infrastructure health monitoring. A blow-by-blow account of the major technology progression in this research field is provided in a chronological order. Detailed applications, key contributions, and performance measures of each milestone publication are presented. Representative technologies are detailed to demonstrate current research trends. A road map for future research is outlined to address contemporary issues such as explainable and physics-informed AI. This paper will provide readers with a lucid memoir of the historical progress, a good sense of the current trends, and a clear vision for future research.
Digital algorithm-guided insulin therapy in home healthcare for elderly persons with type 2 diabetes: A proof-of-concept study
Authors: Kopanz Julia , Mader Julia K. , Donsa Klaus , Libiseller Angela , Aberer Felix , Pandis Marlene , Reinisch-Gratzer Johanna , Ambrosch Gisela C. , Lackner Bettina , Truskaller Thomas , Sinner Frank Michael , Pieber Thomas R. , Lichtenegger Katharina M. 
Published: September 2022

GlucoTab@MobileCare, a digital workflow and decision support system with integrated basal and basal-plus insulin algorithm was investigated for user acceptance, safety and efficacy in persons with type 2 diabetes receiving home health care by nurses. During a three months study nine participants (five female, age 77 ± 10 years, HbA1c 60 ± 13 mmol/mol (study start) vs. 57 ± 12 mmol/mol (study end) received basal or basal-plus insulin therapy as suggested by the digital system. In total 95% of all suggested tasks (blood glucose (BG) measurements, insulin dose calculations, insulin injections) were performed according to the digital system. Mean morning BG was 171 ± 68 mg/dL in the first study month vs. 145 ± 35 mg/dL in the last study month, indicating a reduced glycemic variability of 33 mg/dL (standard deviation). No hypoglycemic episode &lt; 54 mg/dL occurred. User’s adherence was high and the digital system supported a safe and effective treatment. Larger scale studies are needed to confirm findings under routine care.German Clinical Trials Register IDDRKS00015059
Exosomal microRNA panel as a diagnostic biomarker in patients with hepatocellular carcinoma
Authors: Yang Jingwen , Dong Weiwei , Zhang He , Zhao Huixia , Zeng Zhiyan , Zhang Fengyun , Li Qiuwen , Duan Xiaohong , Hu Yanyan , Xiao Wenhua 
Published: September 2022

Background: Diagnostic tools for hepatocellular carcinoma (HCC) are critical for patient treatment and prognosis. Thus, this study explored the diagnostic value of the exosomal microRNA panel for HCC.Methods: Expression profiles of microRNAs in exosomes and plasma of HCC and control groups were assessed using microRNA microarray analysis. Reverse transcription-quantitative PCR was applied to evaluate the expression of candidate microRNAs in blood samples from 50 HCC patients, 50 hepatic cirrhosis patients, and 50 healthy subjects. The area calculated the diagnostic accuracy of the microRNAs and microRNA panel under the receiver operating characteristic curve (AUC).Results: MicroRNA microarray analysis revealed that there were more differentially expressed microRNAs in the exosome HCC group than plasma HCC group. Among the 43 differentially expressed microRNAs contained in both exosomes and plasma, we finally decided to testify the expression and diagnostic significance of microRNA-26a, microRNA-29c, and microRNA-199a. The results indicated that expression of the microRNA-26a, microRNA-29c, and microRNA-199a in both exosomes and plasma was significantly lower in HCC patients compared with hepatic cirrhosis and healthy group. Interestingly, exosomal microRNAs were substantially more accurate in diagnosing HCC than microRNAs and alpha-fetoprotein in plasma. Moreover, the exosomal microRNA panel containing microRNA-26a, microRNA-29c, and microRNA-199a showed high accuracy in discriminating HCC from healthy (AUC = 0.994; sensitivity 100%; specificity 96%) and hepatic cirrhosis group (AUC = 0.965; sensitivity 92%; specificity 90%).Conclusion: This study revealed that the exosomal microRNA panel has high accuracy in diagnosing HCC and has important clinical significance.