bluuebunny/crossref_metadata_2025_split huggingface dataset:
Working length variation during multiple‐visit endodontic treatment: An observational study
Authors: Alovisi Mario , Mirra Davide , Berutti Elio , Multari Stefania , Carpegna Giorgia , Pasqualini Damiano , Scotti Nicola 
Published: October 2022

Abstract
This study investigated variation in working length during multiple‐visit endodontic treatment. Patients (N = 106) with pulpitis or pulp necrosis, with or without apical periodontitis, were included. During the first appointment, glide path was performed with ProGlider and shaping with ProTaper Next. Working length was detected four times. Working length was then re‐recorded prior to filling during the second appointment and a 0.5 mm threshold was selected as the minimum clinically meaningful variation. A logistic regression model was used to evaluate the impact of tooth anatomy, preoperative pulp status, apical periodontitis and lesions of endodontic origin on working length variation. Working length varied between first and second appointments in 34% of patients. The presence of apical periodontitis was the only variable significantly associated with variation in working length (p = 0.011). These data suggest that working length should be re‐checked prior to root canal filling to prevent procedural errors.
The supplementary use of XP‐endo Finisher R after Reciproc enhances the removal of a bioceramic sealer in oval root canals
Authors: Da Silva Vanessa , Loroño Gaizka , Valencia de Pablo Oliver , Estevez Roberto , Conde Antonio J. , Rossi‐Fedele Giampiero , Cisneros Rafael 
Published: October 2022

AbstractThis study compared the performance of Reciproc and Reciproc Blue endodontic files in retreatment time and re‐establishment of apical patency, plus removal of a bioceramic sealer from the canal surface with the supplementary use of the XP‐endo Finisher R. Following preparation, slightly curved oval root canals in mandibular incisors were filled using a corresponding gutta‐percha point and a bioceramic sealer. Apical patency achievement was assessed and the time required to reach the original working length was recorded. The samples were split longitudinally and were photographed to assess the material remaining on the canal walls. No significant differences were observed regarding patency achievement or retreatment times when comparing Reciproc and Reciproc Blue. Significant less material remained on the canal walls when Reciproc was followed by XP‐endo compared with Reciproc alone, and when the data for Reciproc and Reciproc Blue were pooled.
Career proactivity: A bibliometric literature review and a future research agenda
Authors: Jiang Zhou , Wang Ying , Li Wanlu , Peng Kelly Z. , Wu Chia‐Huei 
Published: October 2022

AbstractIndividuals often need to be proactive in order to successfully navigate their career development journeys. To what extent one is vocationally proactive has critical implications for his or her attitudes, behaviors, and other outcomes in career and work‐related settings. However, research in career proactivity has been accumulating from divergent perspectives, resulting in a substantially fragmented literature that has not been comprehensively, objectively synthesized to guide the field to move forward. To advance the domain of career proactivity, this paper synthesizes theoretical and empirical literatures using two major bibliometric analyses. We first analyze the intellectual basis of the career proactivity literature by performing document citation analysis. We then review the developmental trends of main conceptual themes in career proactivity literature using a temporal co‐word analysis. Informed by these bibliometric findings, we propose a roadmap for future research highlighting the need to clear up concepts, account for context, develop new meso‐level theories, and bridge the domains of organizational behavior and vocational development.
Career proactivity: Conceptual and theoretical reflections
Authors: Akkermans Jos , Hirschi Andreas 
Published: October 2022

AbstractThis article adds several conceptual and theoretical reflections to the article “Career proactivity: A bibliometric literature review and a future research agenda” by Jiang et al. The authors conducted a timely and relevant study by analyzing and integrating literature on career proactivity from the domains of organizational and vocational behavior. Prior research has clearly demonstrated that these areas are still largely operating as separate “islands,” both conceptually and methodologically. As such, systematically analyzing the literature and synthesizing the many existing proactivity‐related constructs are important steps forward in taking research on career proactivity to the next level. Though their bibliometric analysis confirms the gap between vocational psychology and OB research, there is also a hopeful message in the article, as several clusters showed considerable connections. Thus, it seems that scholars are starting to build bridges between the islands. Building on their analysis and future research suggestions, in this article, we further explore three specific considerations related to (1) conceptual issues, (2) theoretical issues, and (3) additions to their future research agenda.
Effects of finger and mouse pointing on learning from online split‐attention examples
Authors: Zhang Shirong , de Koning Bjorn B. , Paas Fred 
Published: October 2022

AbstractBackgroundSelf‐management of cognitive load is a recent development in cognitive load theory. Finger pointing has been shown to be a potential self‐management strategy to support learning from spatially separated, but mutually referring text and pictures (i.e., split‐attention examples).AimsThe present study aimed to extend the prior research on the pointing strategy and investigated the effects of finger pointing on learning from online split‐attention examples. Moreover, we examined an alternative pointing strategy using the computer mouse, and a combination of finger pointing and computer‐mouse pointing.SampleOne‐hundred and forty‐five university students participated in the present study.MethodAll participants studied an online split‐attention example about the human nervous system and were randomly allocated to one of four conditions: (1) pointing with the index finger, (2) pointing with the computer mouse, (3) pointing with the index finger and the computer mouse and (4) no pointing.ResultsResults confirmed our main hypothesis, indicating that finger pointing led to higher retention performance than no pointing. However, the mouse pointing strategy and the combined finger and mouse pointing strategy did not show supportive effects.ConclusionsFinger pointing can be used as a simple and convenient self‐management strategy in online learning environments. Mouse pointing may not be as effective as finger pointing.
Laparoscopic D3 oncological resection in splenic flexure cancer: Technical details and its impact on long‐term survival
Authors: Rusli Siti Mayuha , Choo Jeong Min , Lee Tae Hoon , Piozzi Guglielmo Niccolò , Cuellar‐Gomez Hugo , Baek Se Jin , Kwak Jung Myun , Kim Jin , Kim Seon Hahn 
Published: October 2022

AbstractAimThe applicability of laparoscopic D3 oncological resection for splenic flexure cancer (SFC) surgery has not been fully explored due to technical difficulties and variations in surgical procedure. The aim of this work is to describe the feasibility of performing laparoscopic D3 resection in SFC and its impact on long‐term survival.MethodA retrospective study on 47 out of 52 consecutive patients who underwent elective laparoscopic colectomy for SFC from December 2006 until December 2019 at Korea University Anam Hospital was performed. Data on patients’ demographic and clinical features, surgical procedures, intraoperative and postoperative complications, pathological features and follow‐up were collected. Categorical data are expressed as frequencies (n) and percentages (%). Continuous data are expressed as mean ± standard deviation and median (range). The Kaplan–Meier test was used to determine the overall survival (OS), progression‐free survival (PFS) and disease‐free survival (DFS).ResultsThe median age of patients was 67.0 years (range 27–87 years) and 72.3% were men. Ten (21.3%) patients presented with an obstructing tumour and underwent an elective laparoscopic colectomy, while 68.1% of patients presented with Stage II and III disease. The conversion rate was 4.3% and the morbidity rate was 31.9%. There was one postoperative death secondary to splenic infarction and anastomotic leak leading to multi‐organ failure. Four deaths occurred due to disease progression during a median follow‐up of 63.8 months. The rate of recurrence was 20%, the 5‐year OS was 89.6% and the 5‐year PFS was 72.9%. After R0 resection, the 5‐year OS was 91.5% and the 5‐year DFS was 74.5%.ConclusionLaparoscopic D3 colectomy for SFC is feasible, with an acceptable morbidity and long‐term oncological outcome when performed by highly skilled laparoscopic colorectal surgeons with knowledge of the complex anatomy around the splenic flexure. Further randomized trials should be performed to determine the advantage of laparoscopic D3 colectomy over conventional colectomy for SFC.
Systematic literature review on predictive maintenance of vehicles and diagnosis of vehicle's health using machine learning techniques
Authors: Jain Muskan , Vasdev Dipit , Pal Kunal , Sharma Vishal 
Published: October 2022

AbstractMany industries, inclusive of the automobile industry, have shifted their attention toward predictive maintenance. The automobile industry finds predictive maintenance a key player in improving the servicing and vehicles they deliver. It is also vital for the vehicle owners to diagnose the vehicles to prevent risks the vehicle may face by timely servicing. Even though, with so many benefits of predictive maintenance, it is challenging to detect a breakdown in advance in the automobile sector. This is due to the restricted accessibility to sensors and the unavailability of some design applications. However, with the continuous advances in technology, machine learning (ML) methods have come forward as a viable solution to analyze data and develop solutions even when the data is scarce. This article intends to provide the literature review of ML techniques used for predictive maintenance of automobiles and diagnosis of the vehicle's health using ML. This review focuses on machine learning techniques in practice, extraction of data from the onboard diagnosis system and difficulties that models face. The article also explores the possibility and scope of positive work efforts in this area.
Examining the transplant case composition of early‐career transplant surgeons
Authors: Cortez Alexander R. , Delman Aaron M. , Quillin Ralph C. 
Published: October 2022

AbstractFellowship training established by the American Society of Transplant Surgeons and certified by the Transplant Accreditation and Certification Council provides trainees with broad exposure and practice readiness for the core aspects of abdominal transplantation. However, the operative case mix of a new transplant surgeon early in practice is unknown. This study examined the volume and composition of the transplant case mix of early‐career transplant surgeons to better inform residents interested in transplantation about potential career opportunities following fellowship. cas 209 early‐career transplant surgeons were identified from the UNOS database containing encrypted surgeon‐specific identifiers and were included in this study. At 5 years into practice, there were 85 (40.7%) kidney‐predominant, 38 (18.2%) liver‐predominant, and 86 (41.1%) multiorgan transplant surgeons. Comparing surgeon subgroups, multiorgan surgeons performed more transplants in year 5 of practice than both liver‐predominant and kidney‐predominant surgeons (both p < .05). This is the first study to describe the transplant case composition of the early‐career transplant surgeons. This data can be used to inform aspiring transplant surgeons about potential career opportunities and to assist fellowship programs in guiding and mentoring fellows.
Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double‐blind placebo‐controlled cross‐over study
Authors: Ruijs Titia Q. , Koopmans Ingrid W. , de Kam Marieke L. , Tannemaat Martijn R. , Groeneveld Geert Jan , Heuberger Jules A. A. C. 
Published: October 2022

AbstractMeasuring muscle velocity recovery cycles (MVRCs) is a method to obtain information on muscle cell excitability, independent of neuromuscular transmission. The goal was to validate MVRC as a pharmacodynamic (PD) biomarker for drugs targeting muscle excitability. As proof‐of‐concept, sensitivity of MVRC to detect effects of mexiletine, a voltage‐gated sodium channel (Nav) blocker, was assessed. In a randomized, double‐blind, two‐way crossover study, effects of a single pharmacologically active oral dose of 333 mg mexiletine was compared to placebo in 15 healthy male subjects. MVRC was performed predose, and 3‐ and 5‐h postdose using QTrac. Effects of mexiletine versus placebo were calculated using a mixed effects model with baseline as covariate. Mexiletine had significant effects on MVRC when compared to placebo. Early supernormality after five conditioning stimuli was decreased by mexiletine (estimated difference −2.78% [95% confidence interval: −4.16, −1.40]; p value = 0.0003). Moreover, mexiletine decreased the difference in late supernormality after five versus one conditioning stimuli (5XLSN; ED −1.46% [−2.26, −0.65]; p = 0.001). These results indicate that mexiletine decreases the percentage increase in velocity of the muscle fiber action potential after five conditioning stimuli, at long and short interstimulus intervals, which corresponds to a decrease in muscle membrane excitability. This is in line with the pharmacological activity of mexiletine, which leads to use‐dependent NaV1.4 blockade affecting muscle membrane potentials. This study shows that effects of mexiletine can be detected using MVRC in healthy subjects, thereby indicating that MVRC can be used as a tool to demonstrate PD effects of drugs targeting muscle excitability in early phase drug development.
Asynchronized cell division in embryo‐like fossils from the Ediacaran Zhenba microfossil assemblage
Authors: Zhang Yuan , Zhang Xingliang , Liu Cong 
Published: October 2022

AbstractEdiacaran embryo‐like spherical fossils exhibit diverse cell adhesion patterns resembling partial cleavage‐stage embryos of living animals. Two three‐celled specimens characterized by a pair of small cells overlying a large cell have been recovered from the Ediacaran Zhenba microfossil assemblage. Their cell adhesion pattern is highly comparable to a phenomenon reported from the Weng'an biota that was interpreted as fossil embryos undergoing discoidal cleavage. However, our specimens contain fewer cells and thus probably represent developmental precursors of the Weng'an counterparts. Additionally, new material shows several anatomical features that are inconsistent with an embryo interpretation, including (1) an unusually large volume of “blastomeres,” (2) a putative nucleus preserved within the large “yolk cell,” and (3) completely separated cells. Collectively, the Zhenba embryo‐like specimens permit a reconstruction of the consecutive developmental sequence from single‐celled individuals to the three‐celled individuals, leading us to interpret the newly found specimens as products of abnormal development of Ediacaran embryo‐like organisms whose affinity remains unresolved.
Climatic origin of provenances of Corymbia calophylla affects canker disease susceptibility, caused by Quambalaria coyrecup, and interactions with drought stress
Authors: Hossain Mohitul , Veneklaas Erik , Hardy Giles , Poot Pieter 
Published: October 2022

AbstractMany forest ecosystems are in decline around the world due to increasing biotic and abiotic stresses. Marri (Corymbia calophylla) is an endemic and common eucalypt species of southwestern Australia, which is in decline primarily due to stem canker caused by the pathogenic fungus Quambalaria coyrecup. This study determined to what extent disease susceptibility and plant growth were associated with climate at origin for eight provenances of marri. Plants of all provenances were grown in a common garden with or without pathogen inoculation. Disease development and physiological performance of plants were monitored during an initial irrigated and subsequent terminal drought period. Provenances from drier regions were more susceptible to the fungal pathogen than those from wetter regions, having on average 31% higher incidence rates at 20 days post‐inoculation (dpi) and larger canker lesions at 130 dpi (on average 49% increase) and 230 dpi (on average 42% increase). However, canker development for each provenance was fastest during the initial irrigated wetter growing period. Overall, the average relative canker growth rate was 4‐fold higher during the irrigated period compared to the terminal drought period (p < .001). There were no significant differences between the provenances in leaf water status, photosynthetic rates, or relative growth rates (p > .05). Canker infection reduced both photosynthetic rates and growth rates but only during the later part of the terminal drought period, with significant (p < .05) reductions observed in two out of eight provenances, when plants had relatively large canker sizes. This effect tended to be strongest in the provenances from drier regions as they had relatively larger canker sizes than the provenances from wetter regions. We propose that the increased susceptibility of drier provenances is related to their lower exposure to the pathogen in their drier habitats. Since this is potentially due to suboptimal defence responses, using provenances from drier locations to ‘future‐proof’ local restoration outcomes in a drying climate may be counterproductive due to plant–pathogen interactions.
Graphiola phoenicis associated with false smut on Canary Island date palm (Phoenix canariensis) in Korea
Authors: Sung Han‐Jung , Park Ji‐Hyun , Lee Yeong‐Don , Shin Hyeon‐Dong , Lee Sang Hyun 
Published: October 2022

AbstractLeaf spots and smut‐like symptoms have been observed on the Canary Island date palm Phoenix canariensis in Korea since 2021. The fungus associated with the false smut was identified as Graphiola phoenicis based on the morphological characteristics and molecular sequence analysis of the large subunit region of the rDNA. This study reports the novel occurrence of G. phoenicis on P. canariensis in Korea and provides mycological information of the Korean isolates.
Measuring inflation expectations in interwar Britain
Authors: Lennard Jason , Meinecke Finn , Solomou Solomos 
Published: October 2022

AbstractWhat caused the recovery from the British Great Depression? A leading explanation – the ‘expectations channel’ – suggests that a shift in expected inflation lowered real interest rates and stimulated consumption and investment. However, few studies have measured, or tested the economic consequences of, inflation expectations. In this paper, we collect high‐frequency information from primary and secondary sources to measure expected inflation in the United Kingdom between the wars. A high‐frequency vector autoregression suggests that inflation expectations were an important source of the early stages of economic recovery in interwar Britain.
Beyond seizure freedom: Dissecting long‐term seizure control after surgical resection for drug‐resistant epilepsy
Authors: Hsieh Jason K. , Pucci Francesco G. , Sundar Swetha J. , Kondylis Efstathios , Sharma Akshay , Sheikh Shehryar R. , Vegh Deborah , Moosa Ahsan N. , Gupta Ajay , Najm Imad , Rammo Richard , Bingaman William , Jehi Lara 
Published: October 2022

AbstractObjectiveThis study was undertaken to better understand the long‐term palliative and disease‐modifying effects of surgical resection beyond seizure freedom, including frequency reduction and both late recurrence and remission, in patients with drug‐resistant epilepsy.MethodsThis retrospective database‐driven cohort study included all patients with >9 years of follow‐up at a single high‐volume epilepsy center. We included patients who underwent lobectomy, multilobar resection, or lesionectomies for drug‐resistant epilepsy; we excluded patients who underwent hemispherectomies. Our main outcomes were (1) reduction in frequency of disabling seizures (at 6 months, each year up to 9 years postoperatively, and at last follow‐up), (2) achievement of seizure remission (>6 months, >1 year, and longest duration), and (3) seizure freedom at last follow‐up.ResultsWe included 251 patients; 234 (93.2%) achieved 6 months and 232 (92.4%) experienced 1 year of seizure freedom. Of these, the average period of seizure freedom was 10.3 years. A total of 182 (72.5%) patients were seizure‐free at last follow‐up (defined as >1 year without seizures), with a median 11.9 years since remission. For patients not completely seizure‐free, the mean seizure frequency reduction at each time point was 76.2%, and ranged from 66.6% to 85.0%. Patients decreased their number of antiseizure medications on average by .58, and 53 (21.2%) patients were on no antiseizure medication at last follow‐up. Nearly half (47.1%) of those seizure‐free at last follow‐up were not seizure‐free immediately postoperatively.SignificancePatients who continue to have seizures after resection often have considerable reductions in seizure frequency, and many are able to achieve seizure freedom in a delayed manner.
Heat‐triggered thermo‐irreversible gelation of curdlan to control crystallisation and in vitro release of nobiletin
Authors: Li Mengchen , Wang Yueming , Guo Dashan , Zhu Kongdi , Zhang Jiajia , Rong Yujuan , Liang Hongshan , Zhou Bin 
Published: October 2022

SummaryMany kinds of flavonoids with poor water solubility and high crystallisation properties tend to crystallise in the system, which negatively affects their processing, storage and bioavailability. Hence, controlling crystal growth is an effective pathway to achieve stabilisation. Inspired by the properties of heat‐triggered gelation of curdlan (Cur), the nobiletin (NOB) supersaturated solution was mixed with Cur gel under heating treatment, following which the formation of Cur gel might control NOB crystallisation process in situ. The results showed that different proportions of Cur could change the size of the crystals, of which a concentration higher than 4% could better control the crystallisation of NOB. The effect on texture and rheological properties after the addition of NOB was investigated in detail. Finally, in vitro release experiments showed that the gel played a great role in sustained release, greatly improving the release efficiency compared with pure NOB samples. Taken together, this study proposes a simple stabilisation method that initially attempts to overcome some of the bottlenecks in storage and processing of hydrophobic substances.
Life during furlough: Challenges to dignity from a changed employment status
Authors: Hamilton Peter , Harness Oonagh , Griffin Martyn 
Published: October 2022

AbstractIn response to the COVID‐19 virus, the UK government introduced the Job Retention Scheme in March 2020. The scheme, a novelty in the United Kingdom, provided income support to those furloughed from work. In this paper, we examine how individuals in several occupations and organisations experienced furlough and how they were treated during this enforced period of work absence. Beyond describing their experiences during the furlough, we examine how these experiences threatened and challenged their sense of dignity. Experientially we report on furlough as a time that elicited both delight and despair. The analysis of dignity relates to how treatment based on their employment status rendered many employees marginalised and cast adrift.