bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between body composition, physical activity level and Illinois agility test performance in young males and females
Authors: Subak Erdem , Kaya Kaan , Viga Şaban O. , Ocak Muhammed H. , Ağaoğlu Ceren , Bekiroğlu Aslı 
Published: August 2022

Background and Study Aim. Agility performance, which is a skill related to fast change of direction, explosiveness, and quickness, is a vital performance component for team sports. Illuminating factors that affect agility is substantial to understand the ability requirements and improve. This study aims to investigate correlations of the body analyze parameters and agility performance.
Material and Methods. One hundred twenty three young participants (93 male, 30 female) were included in this research. Height, weight, fat (%), fat (kg), fat-free mass (FFM), muscle mass, total body water (TBW, kg, and %), bone mass, basal metabolic rate (BMR), metabolic age, visceral rating, and body mass index (BMI) measured for all participants. Illinois Agility Test (IAT) was used to analyze agility performance. A questionnaire including questions about the physical activity level of participants was applied to all participants after IAT.
Results. Results showed that height was a dominant determinant of IAT performance. There were significant positive correlations between height (negative correlation in women), body weight, fat percentage, fat mass, and visceral rating level (p < 0.05). TBW (%) had a negative relation with IAT duration (p < 0.001). There was a statistically significant difference in terms of IAT between the participants who stated their physical activity levels as low, medium and high (p = 0.025*). Increased daily physical activity level and daily step count increased the agility performance (p < 0.05).
Conclusions. Coaches and athletes should be considered especially body weight, fat (%), hydration status, and daily physical activity level to improve agility performance.
Banff Human Organ Transplant Transcripts Correlate with Renal Allograft Pathology and Outcome: Importance of Capillaritis and Subpathologic Rejection
Authors: Rosales Ivy A. , Mahowald Grace K. , Tomaszewski Kristen , Hotta Kiyohiko , Iwahara Naoya , Otsuka Takuya , Tsuji Takahiro , Takada Yusuke , Acheampong Ellen , Araujo-Medina Milagros , Bruce Amy , Rios Andrea , Cosimi Anthony Benedict , Elias Nahel , Kawai Tatsuo , Gilligan Hannah , Safa Kassem , Riella Leonardo V. , Tolkoff-Rubin Nina E. , Williams Winfred W. , Smith Rex Neal , Colvin Robert B. 
Published: August 2022

Significance Statement
Microarray analysis of renal allograft biopsies has revealed important insights, including TCMR and AMR gene sets, but is limited to specially processed samples without pathology confirmation. We used the NanoString nCounter platform to perform mRNA analysis of archived formalin-fixed paraffin-embedded kidney allograft biopsies with the Banff Human Organ Transplant Panel. We correlated Banff pathology scores in the same tissue block with validated and custom gene sets and showed the importance of capillaritis. We identified subpathological transcripts that standard pathology would not have detected and transcripts, pathology, and clinical variables that predicted graft failure in TCMR and CAMR. These findings highlight the utility of archived samples in transplant pathology research and expand our understanding of the pathogenesis of rejection.

Background
To seek insights into the pathogenesis of chronic active antibody–mediated rejection (CAMR), we performed mRNA analysis and correlated transcripts with pathologic component scores and graft outcomes.

Methods
We utilized the NanoString nCounter platform and the Banff Human Organ Transplant gene panel to quantify transcripts on 326 archived renal allograft biopsy samples. This system allowed correlation of transcripts with Banff pathology scores from the same tissue block and correlation with long-term outcomes.

Results
The only pathology score that correlated with AMR pathways in CAMR was peritubular capillaritis (ptc). C4d, cg, g, v, i, t, or ci scores did not correlate. DSA-negative CAMR had lower AMR pathway scores than DSA-positive CAMR. Transcript analysis in non-CAMR biopsies yielded evidence of increased risk of later CAMR. Among 108 patients without histologic CAMR, 23 developed overt biopsy-documented CAMR within 5 years and as a group had higher AMR pathway scores (P=3.4 × 10–5). Random forest analysis correlated 3-year graft loss with elevated damage, innate immunity, and macrophage pathway scores in CAMR and TCMR. Graft failure in CAMR was associated with TCMR transcripts but not with AMR transcripts, and graft failure in TCMR was associated with AMR transcripts but not with TCMR transcripts.

Conclusions
Peritubular capillary inflammation and DSA are the primary drivers of AMR transcript elevation. Transcripts revealed subpathological evidence of AMR, which often preceded histologic CAMR and subpathological evidence of TCMR that predicted graft loss in CAMR.
Isıl işlem uygulanmış çam odun örneklerinin hızlandırılmış yaşlandırma testi sonrası renk ve pürüzlülük değerlerinin incelenmesi
Authors: CAN Ahmet 
Published: August 2022

Bu çalışmada, sarıçam (Pinus sylvestris L.) odununun oksijen (açık sistem) ve vakum altında (kapalı sistem) ısıl işlemi sonrası hızlandırılmış yaşlandırma testi performansı incelenmiştir. Örnekler 75 (Radyal) × 15 (Teğet) × 150 (Lifler) mm boyutlarında çam diri odun kısmından hazırlanmıştır. Hızlandırılmış yaşlandırma testi sonrası örneklerin yüzey pürüzlülüğü ve renk ölçümü gerçekleştirilmiştir. Sonuçlara göre minimum renk değişimi 190 °C’de kapalı sistemde (VHT) gerçekleştirilen ısıl işlem sonrası elde edilmiştir. Kapalı sistemde ısıl işlem görmüş sarıçam örneklerinin yüzey pürüzlülük parametreleri ısıl işlem sıcaklığındaki artışla birlikte artmıştır. Kapalı sistemde gerçekleştirilen ısıl işlemde, açık sistemde (HT) gerçekleştirilen ısıl işleme kıyasla daha düşük pürüzlülük değerleri elde edilmiştir. Hızlandırılmış yaşlandırma süresinin artışına paralel olarak toplam renk değişimi ve pürüzlülük değerleri artış göstermiştir.
A Project Lifetime Approach to the Management of Induced Seismicity Risk at Geologic Carbon Storage Sites
Authors: Templeton Dennise C. , Schoenball Martin , Layland-Bachmann Corinne E. , Foxall William , Guglielmi Yves , Kroll Kayla A. , Burghardt Jeffrey A. , Dilmore Robert , White Joshua A. 
Published: August 2022

AbstractThe geologic storage of carbon dioxide (CO2) is one method that can help reduce atmospheric CO2 by sequestering it into the subsurface. Large-scale deployment of geologic carbon storage, however, may be accompanied by induced seismicity. We present a project lifetime approach to address the induced seismicity risk at these geologic storage sites. This approach encompasses both technical and nontechnical stakeholder issues related to induced seismicity and spans the time period from the initial consideration phase to postclosure. These recommendations are envisioned to serve as general guidelines, setting expectations for operators, regulators, and the public. They contain a set of seven actionable focus areas, the purpose of which are to deal proactively with induced seismicity issues. Although each geologic carbon storage site will be unique and will require a custom approach, these general best practice recommendations can be used as a starting point to any site-specific plan for how to systematically evaluate, communicate about, and mitigate induced seismicity at a particular reservoir.
Análisis diferencial de variables psicológicas relacionadas con el compromiso para la práctica deportiva en universitarios durante el confinamiento por la COVID-19
Authors: Álvarez-Álvarez Mario , Ramón-Ramón Franklin , Jiménez-Castuera Ruth , Díaz-Contreras Karol , Leyton-Román Marta 
Published: August 2022

En la actualidad los componentes psicológicos han alcanzado una importancia muy notable en la adquisición de comportamientos saludables. Por lo tanto, este estudio analiza las diferencias entre variables psicológicas que se relacionan con la práctica deportiva en estudiantes universitarios durante el confinamiento causado por la COVID-19. El estudio tuvo una muestra de 1239 participantes (765 varones y 474 mujeres), de edades comprendidas entre los 16 y 45 años (M = 21,44; DT = 3,94). Se utilizó un cuestionario que incluyó la Behavioral Regulation in Sport Questionnaire (BRSQ), la Escala de las Necesidades Psicológicas Básicas en el Ejercicio; la Escala de Autoeficacia para la Actividad Física; y la Escala de Grado de Compromiso Deportivo. Los resultados más relevantes muestran diferencias significativas (p<0,01) en favor del género masculino en casi todas las variables psicológicas excepto en la desmotivación, así mismo en lo que respecta a la motivación controlada y desmotivación, se encontraron diferencias significativas entre las localidades pequeñas y grandes, siendo los valores más altos en las primeras (p<0,05 y <0,01). Se discuten los resultados con objeto de determinar las diferencias en cuanto a qué componentes psicológicos permitirían plantear intervenciones que sean más efectivas para lograr la práctica regular de actividades deportivas así como su compromiso y adherencia, mediante el uso de estrategias que vayan encaminadas a fomentar la motivación autónoma de los universitarios y contrarrestar los efectos de la motivación controlada y la desmotivación.
Aqueous Leaf Extract of Chromolaena odorata Attenuates Methotrexate-Induced Hepatotoxicity in Wistar Rats
Authors: Ikponmwosa Bridget , Usunobun Usunomena 
Published: August 2022

Methotrexate (MTX) usage, despite its toxicity in body organs, has increased steadily over the years due to its broad applicability for treating different ailments, including various forms of cancer. Certain plant species have been shown to possess therapeutic properties by offering a protective effect against drug side effects. Thus, the current study was carried out to evaluate the potential of aqueous Chromolaena odorata leaf extract (AEOC) to attenuate the effect of MTX-induced hepatotoxicity in Wistar rats. The study divided thirty (30) male Wistar rats into five groups consisting of six each: Group I (control), Group II (AEOC at 250 mg/kg BW), Group III (MTX at 7 mg/kg BW), Group IV (AEOC at 250 mg/kg BW + MTX at 7 mg/kg BW), and Group V (Vitamin C (100 mg/kg BW) + MTX at 7 mg/kg BW). Chromolaena odorata and Vitamin C was administered for ten consecutive days, while MTX was administered on day 8 for three consecutive days. Rats were sacrificed 24hrs after the last administration. Serum collected was used for the determination of Aspartate Aminotransferase (AST), Alanine transaminase (ALT), Albumin (ALB), Total Bilirubin (TB), and Total protein (TP), while liver tissue was used for assessment of Superoxide Dismutase (SOD), Malondialdehyde (MDA) and Catalase (CAT) as well as histopathological analysis. The result showed a significant increase in the level of SOD, CAT and a significant reduction in MDA in Chromolaena odorata or Vitamin C treated groups compared with MTX. Furthermore, Chromolaena odorata or Vitamin C significantly reduced liver function enzymes and Total Bilirubin levels while increasing synthetic molecules compared to the MTX group. Chromolaena odorata attenuated the toxic effect of MTX, which was corroborated by histopathological analysis. In conclusion, Chromolaena odorata attenuated MTX-induced hepatotoxicity by enhancing antioxidant status; thus, scavenging free radicals and reducing oxidative stress.
Pandemia de COVID-19 e a implementação de teleatendimentos em saúde mental: um relato de experiência na Atenção Básica.
Authors: Bortoleti de Araujo Maria Paula , Pacciulio Ana Lívia Mota , Montanha Lilian Thiago , Emerich Bruno Ferrari , Pellati Giovana , Onocko Campos Rosana 
Published: August 2022

Resumo: Objetivo- O presente trabalho objetiva apresentar as ações realizadas por duas residentes (psicóloga e enfermeira) de saúde mental em um Centro de Saúde numa cidade de grande porte no interior de São Paulo, durante a pandemia da COVID-19. Método- Trata-se de um relato de experiência, em que procuramos descrever a implementação de teleatendimentos com os usuários da saúde mental, realizados em caráter emergencial a fim de garantir a manutenção do acompanhamento dos pacientes. Procuramos promover um espaço de escuta e abrir um canal de comunicação com estes usuários, a fim de acolher as demandas e prevenir possíveis agravamentos de sofrimento psíquico, orientar e, também, tranquilizar a população com informações confiáveis a respeito da pandemia. Resultados- Esta estratégia de cuidado se mostrou uma potente ação terapêutica, promovendo a proteção da saúde mental dos usuários e reforçando diretrizes do SUS. Considerações Finais- Espera-se que esse trabalho possa contribuir para a reflexão sobre a importância da continuidade do cuidado à saúde mental na Atenção Básica no contexto da pandemia da COVID-19.
Evaluation of intoxication in patients with acute impaired consciousness using rapid urine test tape; a diagnostic accuracy study
Authors: Hashemi Behrooz , Eshghi Zahra , Ghabousian Amir , Safari Saeed 
Published: August 2022

Objective: Determining the exact underlying etiology of loss of consciousness (LOC) can become a real challenge for physicians due to the broadness of differential diagnoses. The current study aimed to assess the accuracy of a commercially available strip for urine drug screening, in patients presenting with LOC.
Methods: One hundred fifty patients with LOC were enrolled in the current cross-sectional study. The diagnostic accuracy of a multidrug urinary strip rapid test was evaluated in comparison to blood analysis as the reference test, and the screening performance characteristics of the rapid test for each substance were estimated.
Results: The average age of patients was 46.21±18.59 years (72.67% male). The most frequent false positive results of the test were related to Benzodiazepine (21.5%), Methamphetamine (7.5%), and Tramadol (5.4%), respectively. The screening performance characteristics of the test tape were the best in detection of Amitriptyline with 100.0% (95% CI: 30.99 – 100.0) sensitivity, Cocaine with 100.0% (95% CI: 5.46 – 100.0) sensitivity, and Methadone with 91.54% (95% CI: 81.88 – 96.51) sensitivity, respectively.
Conclusion: The current study reveals that employing a urinary strip test for detecting drug intoxication in the setting of emergency department can lead to significant false positive and negative results. Accordingly, relying on a urine drug screen to determine the underlying etiology of LOC should be done with caution.
The Effect of Mergers and Acquisitions Strategies on Financial Performance of Commercial Banks in Kenya
Authors: Gachigo Justin , Ondigo Herick , Aduda Josiah , Onsomu Zipporah 
Published: August 2022

The operating environment for commercial banks in Kenya has become very dynamic and highly competitive. The witnessed cases of bank failure and poor financial performance have made commercial banks develop strategies to improve their financial performance, remain competitive, and meet the regulator's compliance requirements. Mergers and Acquisitions Strategies are on the rise as a strategy aimed to alleviate the ailing sector. In light of this, the purpose of this study was to examine the impact on financial performance of commercial banks in Kenya as a result of mergers and acquisitions Strategies. Operating efficiency and market share impact on the financial performance of commercial banks in Kenya formed the specific objectives. The study objectives were supported by synergies theory, resource-based view theory and agency theory. The study adopted a correlational descriptive research design, including cross-sectional data analysis. By the year 2017, 30 commercial banks in Kenya had considered mergers and acquisitions strategies were considered as the population of this study. An average of three-year ratios was computed in both pre-merger and post -acquisition periods inorder to assess the impact financial performance. The years of the deal were excluded. The mean difference between the pre-Mergers and Acquisitions Strategies and post-Mergers and Acquisitions Strategies ratios was tested using the T-test.The findings were that Mergers and Acquisitions Strategies have a statically positive significant relationship with the dependent variable. Recommends from the study are that, the policymakers create policies that facilitate and encourage commercial banks to employ mergers and acquisition strategies to achieve better financial performance.
Effet de la Profondeur de Semis des Semences sur la Qualité Germinative des Graines de Pterocarpus Erinaceus Poir., 1804 (Fabaceae)
Authors: Patrice Houphouet Yao , Henri Kouassi Kouadio , Innocent Adji Beda , Sélastique Akaffou Doffou , Jerôme Duminil , Annabel Sabatier Sylvie 
Published: August 2022

Pterocarpus erinaceus est une espèce largement utilisée par les populations des zones sahéliennes et soudaniennes. Cependant, cette espèce est menacée par l’exploitation abusive des peuplements naturels. La présente étude vise à déterminer un idéotype de profondeur de semis des graines de Pterocarpus erinaceus pour relever le taux de germination de production des plantules dans le cadre de sa régénération. Pour ce faire, les graines ont été décortiquées et enfouies à différentes profondeurs (0,5 cm, 1 cm, 1,5 cm) sans traitement spécifique. L’évaluation de la vigueur des plantules a été basée sur des paramètres morphologiques qui sont : la hauteur (Ht), le diamètre au collet (Dcol), le nombre de feuille (Nf), la longueur des feuilles (Logfe) et la largeur des feuilles (Largfe). Les résultats ont montré que les meilleurs taux de germination (90,66 %) sont obtenus avec les semis enfouis à 0,5 cm du sol. Les faibles taux (41 %) de germinations ont été obtenus avec les semences enfouies à 1,5 cm. Cette expérimentation dénote que le semis superficiel des graines de Pterocarpus erinaceus est recommandé pour sa multiplication.

Pterocarpus erinaceus is a species widely used by populations in the Sahelian and Sudanese zones. This species, however, is threatened by the abusive exploitation of natural stands. This paper focuses on determining a seedling depth ideotype of Pterocarpus erinaceus seeds in recording the germination rate of seedling production as part of its regeneration. In doing this, the seeds were shelled and buried at different depths (0,5 cm, 1 cm, 1,5 cm) without specific treatment. The evaluation of the sturdiness of the seedling was based on morphological parameters which are: height (Ht), neck diameter (Dcol), number of leaves (Nf), length of leaves (Logfe), and width of leaves (largfe). The results showed that the best germination rates (90,66 %) are obtained with seedlings buried at 0,5 cm from the ground. Low germination rates (41 %) were obtained with seeds buried at 1,5 cm. This experiment indicates that the superficial sowing of the seeds of Pterocarpus erinaceus is recommended for its multiplication.
The Role of the ASEAN Socio-Cultural Community in Overcoming the COVID-19 Pandemic
Authors: Camelia A Indah , Koesrianti  , Lina Hastuti  
Published: August 2022

The COVID-19 pandemic is described as circumstances often interchangeably in social and medical contexts as non-boundary spread and directly affected a wide range of human life and a non-traditional security threat. The pandemic has had adverse consequences on the economy, and health and psychology have suffered. In 2020, ASEAN held an extraordinary summit on COVID-19 to accelerate resilience to the pandemic as a regional response; however, a solid commitment and comprehensive foundation are critical focal points for dealing with infectious diseases. Therefore, ASEAN member states should create a permanent mechanism to deal with current and future pandemics by providing a strategic long-term plan, an annual work plan, effective monitoring systems, and quality assurance by strengthening the ASEAN Socio-Cultural Community’s role as an open and dynamic entity within the ASEAN Community. Doctrinal research based on normative legal and conceptual approaches was conducted as methods for this study.
Mental Health and Behavioural Interventions for Children and Adolescents with Incarcerated Parents: A Systematic Review
Authors: Merhi Dania , Demou Evangelia , Niedzwiedz Claire 
Published: August 2022

Abstract
Parental incarceration is a traumatic experience that affects millions of children and adolescents worldwide. This population is at an increased risk of suffering from mental health problems and problematic behaviors that can lead to future delinquency, furthering the inter-generational cycle of criminality. The aim of this systematic review is to evaluate the effectiveness of different types of interventions for the mental health and behavior of children and adolescents with incarcerated parents. The following databases were searched to retrieve relevant studies from 1995 to 2021: PsycINFO, Psychology and Behavioural Sciences Collection, Child Development and Adolescent Studies, SocINDEX, CINAHL, MEDLINE, Embase, and the Web of Science Core Collection. Quality assessment was performed using the Critical Appraisal Skills Programme qualitative checklist and the “Quality Assessment Tool for Quantitative Studies” developed by the Effective Public Health Practice Project. The initial search yielded 2,711 records and 16 studies met the inclusion criteria. The narrative synthesis conducted determined that interventions focusing on improving caregiver outcomes and support, and maternal attachment may be effective in reducing mental health problems and problematic behaviors, however, findings need to be evaluated with regards to the included studies’ quality of evidence since many (n = 7) had a weak rating. Future research should aim to conduct a comparative analysis between the effectiveness of different types of interventions, while focusing on improving the quality of the evidence.
Fstl1 suppresses breast cancer lung metastasis by inhibiting M2-like tumor-associated macrophages recruitment towards the lung
Authors: yang ying , Lu Tao , Jia Xiao-wei , Gao Yan 
Published: August 2022

Abstract
Immune cell infiltration in the tumor microenvironment is associated with cancer prognosis. Tumor-associated macrophages (TAMs) play an essential role in tumor initiation, progression, and metastasis. Follistatin-like protein 1 (Fstl1), a glycoprotein widely expressed in human and mouse tissues, is a tumor suppressor in various cancers and a regulator in macrophage polarization. However, how Fstl1 affects the crosstalk between breast cancer cells and macrophages remains unclear. Analyzing the public data, we found that Fstl1 expression significantly decreases in breast cancer tissues compared with normal breast tissues, and high expression of Fstl1 in patients means prolonged survival. Using flow cytometry, we found that total macrophages and M2-like macrophages increased in the metastatic lung tissues during breast cancer lung metastasis of Fstl1+/− mice. Cellular experiments in vitro showed that Fstl1 inhibited macrophage migration towards 4T1 cells via decreasing colony stimulating factor 1 (CSF-1), transforming growth factor-β1 (TGFB1) and vascular endothelial growth factor-α (VEGF-α) expression of 4T1 cells. We demonstrated that Fstl1 inhibited M2-like tumor-associated macrophages recruitment towards the lung and suppressed TGFB1/Smad2/3 pathway and relevant cytokines expression of 4T1 cells. Thereby we find a potential therapeutic strategy contributing to breast cancer.