bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of externally attached archival data loggers on the short-term dispersal behaviour and migration speed of European eel (Anguilla anguilla L.)
Authors: Verhelst Pieterjan , Aarestrup Kim , Hellström Gustav , Jepsen Niels , Koed Anders , Reubens Jan , Sjöberg Niklas , Svendsen Jon Christian , Kristensen Martin Lykke 
Published: March 2022

Abstract
Background
Externally attached archival data logging tags are increasingly used to unravel migration routes of fish species at sea. Due to the relatively large size of the tags, their application on seaward migrating anguillid eels often forms a challenge in terms of feasibility and impact on the eel’s swimming performance. In this study, we investigated the impact of externally attached pop-up data storage tags (PDSTs) on the departure direction, time spent at the release location and ground speed of European eels (Anguilla anguilla).

Results
We tagged 66 eels with internal acoustic transmitters of which half of the eels were additionally tagged with externally attached PDSTs. A network of acoustic receivers allowed us to analyse if the dispersal behaviour (i.e. residence time and departure direction) from the release site differed between eels tagged with and without the PDSTs. In addition, we tracked the eels for ca. 83 km in the marine environment and determined their migration speed. The results showed no differences between eels tagged with or without external PDSTs in respect of the external tagging effect on residence time (n = 60), departure direction at the release site (n = 60) or on the migration speed (n = 20).

Conclusions
We conclude that the impact of the PDSTs is minimal on these metrics for at least the first part of the marine migration. While these field-based findings suggest that anguillid eels may be largely unaffected by the applied PDSTs, we recognize that more research is needed in both the field and the laboratory to study the impact of PDSTs and externally attached tags in general on fish swimming performance and energy expenditure. This can help interpret the results from the field, but also aid developing more hydrodynamic tag shapes or improved attachment methods.
The bacterial community of childcare centers: potential implications for microbial dispersal and child exposure
Authors: Beasley D. E. , Monsur M. , Hu J. , Dunn R. R. , Madden A. A. 
Published: March 2022

AbstractBackgroundBacterial communities within built environments reflect differences in sources of bacteria, building design, and environmental contexts. These communities impact the health of their occupants in many ways. Children interact with the built environment differently than do adults as a result of their unique behaviors, size, and developmental status. Consequently, understanding the broader bacterial community to which children are exposed will help inform public health efforts and contribute to our growing understanding of the bacterial community associated with childcare centers.MethodsWe sampled childcare centers to survey the variation in bacterial community composition across five surfaces found inside and outside twelve classrooms and six centers using 16S rRNA marker gene amplicon sequencing. We then correlated these bacterial community analyses of surfaces with environmental and demographic measures of illumination and classroom occupant density.ResultsThe childcare environment was dominated by human-associated bacteria with modest input from outdoor sources. Though the bacterial communities of individual childcare centers differed, there was a greater difference in the bacterial community within a classroom than among centers. Surface habitats—fomites—within the classroom, did not differ in community composition despite differing proximity to likely sources of bacteria, and possible environmental filters, such as light. Bacterial communities did correlate with occupant density and differed significantly between high and low usage surfaces.ConclusionsOur results suggest built environments inhabited by young children are similar to functionally equivalent built environments inhabited by adults, despite the different way young children engage with their environment. Ultimately, these results will be useful when further interrogating microbial dispersal and human exposure to microorganisms in built environments that specifically cater to young children.
Does Vibration Foam Roller Influence Performance and Recovery? A Systematic Review and Meta-analysis
Authors: Alonso-Calvete Alejandra , Lorenzo-Martínez Miguel , Padrón-Cabo Alexis , Pérez-Ferreirós Alexandra , Kalén Anton , Abelairas-Gómez Cristian , Rey Ezequiel 
Published: March 2022

Abstract
Background
Foam rolling has been extensively investigated, showing benefits in performance and recovery. Recently, vibration has been added to foam rollers, with hypothesized advantages over conventional foam rollers. However, there is no systematic evidence in this regard.

Objective
To carry out a systematic review and meta-analysis about the effects of vibration foam roller (VFR) on performance and recovery.

Methods
A systematic search was conducted in PubMed/MEDLINE, Web of Science and SportDiscus according to the PRISMA guidelines. The outcomes included performance (jump, agility and strength) and recovery variables (blood flow, pain and fatigue) measured after an intervention with VFR. The methodological quality was assessed with the PEDro scale. A random-effects model was used to perform the meta-analysis.

Results
Initially, 556 studies were found and after the eligibility criteria 10 studies were included in the systematic review and 9 in the meta-analysis. There was no significant effects on jump performance (SMD = 0.14 [95% CI − 0.022 to 0.307]; p = 0.101; I2 = 1.08%) and no significant beneficial effects were reported on isokinetic strength (SMD = 0.16 [95% CI − 0.041 to 0.367]; p = 0.117; I2 = 9.7%). Recovery appears to be enhanced after VFR interventions, but agility does not seem to increase after VFR interventions.

Conclusion
This systematic review and meta-analysis suggest that VFR could have great potential for increasing jump performance, agility, strength and enhancing recovery. Further research is needed to confirm the effects of VFR on performance and recovery.
Trial Registration This investigation was registered in PROSPERO with the code CRD42021238104.
What works for peer review and decision-making in research funding: a realist synthesis
Authors: Recio-Saucedo Alejandra , Crane Ksenia , Meadmore Katie , Fackrell Kathryn , Church Hazel , Fraser Simon , Blatch-Jones Amanda 
Published: March 2022

Abstract
Introduction
Allocation of research funds relies on peer review to support funding decisions, and these processes can be susceptible to biases and inefficiencies. The aim of this work was to determine which past interventions to peer review and decision-making have worked to improve research funding practices, how they worked, and for whom.

Methods
Realist synthesis of peer-review publications and grey literature reporting interventions in peer review for research funding.

Results
We analysed 96 publications and 36 website sources. Sixty publications enabled us to extract stakeholder-specific context-mechanism-outcomes configurations (CMOCs) for 50 interventions, which formed the basis of our synthesis. Shorter applications, reviewer and applicant training, virtual funding panels, enhanced decision models, institutional submission quotas, applicant training in peer review and grant-writing reduced interrater variability, increased relevance of funded research, reduced time taken to write and review applications, promoted increased investment into innovation, and lowered cost of panels.

Conclusions
Reports of 50 interventions in different areas of peer review provide useful guidance on ways of solving common issues with the peer review process. Evidence of the broader impact of these interventions on the research ecosystem is still needed, and future research should aim to identify processes that consistently work to improve peer review across funders and research contexts.
Transthoracic echocardiography indices as a biomarker in patients with embolic stroke of undetermined source
Authors: Tawfik Mohamed M. 
Published: March 2022

Abstract
Background
Embolic stroke of undetermined source (ESUS) refers to a nonlacunar, nonatherosclerotic infarct in the absence of cardioembolic source or other specific causes of stroke. The presence of ESUS strokes indicates that the conventional risk factors cannot fully account for the pathogenesis of stroke. It is very important to detect useful biomarkers of the risk of ESUS for appropriate 2ry prevention.

Results
The present study showed significant increase in left ventricular hypertrophy (LVH) measured by left ventricular mass index and increased left atrial volume index, measuring left atrial dilatation, among ESUS patients.

Conclusions
Patients with ESUS tended to have Echocardiographic features of heart failure with a preserved ejection fraction (HFpEF) as LVH and left atrial dilatation. Therefore, they should be considered as biomarkers for cardioembolic cerebrovascular accidents with the consideration of anticoagulation with new oral anticoagulants as a primary preventive measure.
A new aspect on the correlation of ten SNPs in MIR and their target genes in dopaminergic pathways in schizophrenia
Authors: Molaei Ali , Agahi Mohadeseh , Malekian Mahtash , Moradhasel Bahareh , Tajrezaee Ardalan , Lajevardi Ava , Salahshourifar Iman , Mahdavi Hezaveh Niloufar , Javadi Gholamreza , Noormohammadi Zahra 
Published: March 2022

AbstractBackgroundSchizophrenia (SCZ) is a severe mental disorder in which people interpret reality abnormally. Different studies indicated a complex polygenic control over SCZ. In the present study, we investigated the potential correlation between ten SNPs among MicroRNA (MIR) and their target genes; rs369770942, rs143525573, rs200982455, rs530404895, rs753764536, rs374732351, rs4680, rs165599, rs340597269, and rs10759, and schizophrenia in the Iranian population.ResultsThe results revealed that the T allele in rs200982455 increased the risk factor by 3.19 times. We obtained a significant association between rs165599 and schizophrenia in codominant, dominant, and overdominant inheritance models (P = 0.016,P = 0.01,P = 0.004, respectively). Moreover, the risk of schizophrenia increased in the presence of the G allele in rs165599 up to 2.12, 2.35, and 2.28 times, respectively. The A allele in rs10759 increased the risk factor up to 1.05 times.ConclusionOur finding showed that some of the studied SNPs within the genes and MIRs involved in the dopaminergic pathway may consider as a biomarker in the diagnostic patterns in Schizophrenia.
Single injection of very mild dose botulinum toxin in the vastus lateralis improves testicular spermatogenesis and sperm motility in ageing experimental mice
Authors: Radhakrishnan Risna Kanjirassery , Ravichandran Sowbarnika , Sukesh Aishwarya , Kadalmani Balamuthu , Kandasamy Mahesh 
Published: March 2022

AbstractBackgroundBotulinum toxin (BoNT) is a widely used therapeutic agent that blocks the excessive release of acetylcholine at the neuromuscular junction. Previously, repeated intracremasteric injections and slight overdose of BoNT have been reported to induce adverse effects in the testicular parameter of experimental rodents. However, a mild dose of BoNT is highly beneficial against skin ageing, neuromuscular deficits, overactive urinary bladder problems, testicular pain and erectile dysfunctions. Considering the facts, the possible therapeutic benefits of BoNT on the testis might be achieved at a very minimal dosage and via a distal route of action. Therefore, we revisited the effect of BoNT, but with a trace amount injected into the vastus lateralis of the thigh muscle, and analyzed histological parameters of the testis, levels of key antioxidants and sperm parameters in ageing experimental mice.ResultsExperimental animals injected with 1 U/kg bodyweight of BoNT showed enhanced spermatogenesis in association with increased activities of key antioxidants in the testis, leading to enhanced amount of the total sperm count and progressive motility.ConclusionsThis study signifies that a mild intramuscular dose of BoNT can be considered as a potent treatment strategy to manage and prevent male infertility.
Safety and efficacy of percutaneous patent ductus arteriosus closure: a multicenter Egyptian experience
Authors: Nour Amira , Abdelrazik Yasmeen , Huessin Safaa , Kamel Heba 
Published: March 2022

AbstractBackgroundTranscatheter closure of patent ductus arteriosus (PDA) has gained acceptance over the last two decades, replacing the surgery in more than 90% of the cases, so the safety and efficacy of transcather closure of PDA have been evaluated by studying different experiences from different centers in developing countries. The aim is to report our experience with PDA transcather closure, with focus on the adverse events and complications faced during the procedure.ResultsOutcome data on PDA transcatheter closure were collected from two different tertiary centers in a multicenter registry. During the period from June 2017 till January 2021, 308 PDA closure were recorded, using device in 197 (64%) and coils in 111 (36%) patients, most of the patients were in pediatric age group from 6 months to 6 years and only 10 patients (3.2%) were adults. Most patients had isolated PDA of 92%, and 9 (2.9%) patients had residual PDAs either post-surgical or transcatheter closure. Median minimum PDA diameter was 2.8 mm (range 1–7.6 mm; IQR 1.8–3.8 mm). The procedure was successful in 293 patients (95%). Complications occurred in 15/308 patients (5%), and only 6 (2%) of them were major complications, but none was life threating. Frequent complications were device embolization (2%), hemolysis (1%), arrhythmia (1%). Younger age, low body weight and longer procedure time were associated with a high complication rate (p < 0.005). Device-related complications were more common than coil-related complications (2.5% versus 0.5%).ConclusionsAlthough transcatheter closure of PDA is considered to be effective procedure with low complications rate, however, complications should be anticipated and managed properly.
Opportunities to improve policy dissemination by tailoring communication materials to the research priorities of legislators
Authors: Smith Natalie R. , Mazzucca Stephanie , Hall Marissa G. , Hassmiller Lich Kristen , Brownson Ross C. , Frerichs Leah 
Published: March 2022

Abstract
Background
Communicating research to policymakers is a complex and difficult process. Ensuring that communication materials have information or design aspects that appeal to groups of policymakers with different priorities could be a substantive improvement over current dissemination approaches. To facilitate a more nuanced design of policy communication materials and message framing, we identified and characterized groups of state legislators based on how they prioritize different characteristics of research.

Methods
We used deidentified data collected in 2012 on 862 state legislators belonging to the US liberal-moderate-conservative ideological spectrum and from all 50 US states. Legislators were grouped using latent class analysis based on how they prioritized 12 different characteristics of research (e.g., research is unbiased, presents data on cost-effectiveness, policy options are feasible). We fit initial models using 1–6 group solutions and chose the final model based on identification, information criteria, and substantive interpretation.

Results
Most legislators placed a high priority on research that was understandable (61%), unbiased (61%), available at the time that decisions are made (58%), and brief and concise (55%). The best model identified four groups of state legislators. Pragmatic consumers (36%) prioritized research that was brief and concise, provided cost-effectiveness analyses, and was understandably written. Uninterested skeptics (30%) generally did not place a high priority on any of the research characteristics. Conversely, one-quarter of legislators (25%) belonged to the Highly Informed Supporters group that placed a high priority on most characteristics of research. Finally, Constituent-Oriented Decision Makers (9%) prioritized research that was relevant to their constituents, delivered by someone they knew or trusted, available at the time decisions were made, and dealt with an issue that they felt was a priority for state legislative action.

Conclusions
To maximize the impact of dissemination efforts, researchers should consider how to communicate with legislators who have distinct preferences, values, and priorities. The groups identified in this study could be used to develop communication materials that appeal to a wide range of legislators with distinct needs and preferences, potentially improving the uptake of research into the policymaking process. Future work should investigate how to engage skeptical legislators.
The Arg82Cys Polymorphism of the Protein Nepmucin Implies a Role in HDL Metabolism
Authors: Metz Sophia , Krarup Nikolaj T , Bryrup Thomas , Støy Julie , Andersson Ehm A , Christoffersen Christina , Neville Matt J , Christiansen Malene R , Jonsson Anna E , Witte Daniel R , Kampmann Ulla , Nielsen Lars B , Jørgensen Niklas R , Karpe Fredrik , Grarup Niels , Pedersen Oluf , Kilpeläinen Tuomas O , Hansen Torben 
Published: March 2022

Abstract

Context
Blood lipid levels are linked to the risk of cardiovascular disease and regulated by genetic factors. A low-frequency polymorphism Arg82Cys (rs72836561) in the membrane protein nepmucin, encoded by CD300LG, is associated with lower fasting concentration of high-density lipoprotein cholesterol (HDLc) and higher fasting triglycerides. However, whether the variant is linked to postprandial lipids and glycemic status remains elusive.

Objective
Here, we augment the genetic effect of Arg82Cys on fasting plasma concentrations of HDL subclasses, postprandial lipemia after a standardized high-fat meal, and glycemic status to further untangle its role in HDL metabolism.

Methods
We elucidated fasting associations with HDL subclasses in a population-based cohort study (Oxford BioBank, OBB), including 4522 healthy men and women. We investigated fasting and postprandial consequences on HDL metabolism in recall-by-genotype (RbG) studies (fasting: 20 carrier/20 noncarrier; postprandial: 7 carrier/17 noncarrier), and shed light on the synergistic interaction with glycemic status.

Results
A lower fasting plasma concentration of cholesterol in large HDL particles was found in healthy male carriers of the Cys82 polymorphism compared to noncarriers, both in the OBB (P = .004) and RbG studies (P = .005). In addition, the Cys82 polymorphism was associated with low fasting plasma concentrations of ApoA1 (P = .008) in the OBB cohort. On the contrary, we did not find differences in postprandial lipemia or 2-hour plasma glucose levels.

Conclusion
Taken together, our results indicate an association between the Arg82Cys variant and a lower concentration of HDL particles and HDLc, especially in larger HDL subclasses, suggesting a link between nepmucin and HDLc metabolism or maturation.
Safer If Connected? Mobile Technology and Intimate Partner Violence
Authors: Pesando Luca Maria 
Published: March 2022

Abstract
Mobile phones are an invaluable economic asset for low-income individuals and an important tool for strengthening social ties. They may also help women overcome physical boundaries, especially those who are separated from support networks and are bound within their husbands' social spheres. Using micro-level data on women and men from recent Demographic and Health Surveys, including new information on mobile phone ownership, this study examines whether women's ownership of mobile phones is associated with their likelihood of having experienced intimate partner violence (IPV) across 10 low- and middle-income countries. Findings show that women's ownership of mobile phones is associated with a 9%–12% decreased likelihood of emotional, physical, and sexual violence over the previous 12 months, even after controlling for characteristics proxying for socioeconomic status, household resources, and local development within the community. Estimates are negative in seven out of the 10 countries and results are robust to the use of nonparametric matching techniques and instrumental variables built through georeferenced ancillary sources. In exploring two potential mechanisms, I show that mobile phone ownership is positively associated with women's decision-making power within the household (decision-making power) and male partners' lower acceptability of IPV (attitudes). Findings speak to scholars and policymakers interested in how technology diffusion relates to dynamics of women's empowerment and global development.
Metal-Free Aerobic C–H Oxidation of Methylarenes to Aromatic Aldehydes by Sulfur-Containing Tetracyclic Compounds as Visible-Light Photocatalysts
Authors: Shibata Takanori , Akino Mika , Sekine Ayato , Ito Mamoru 
Published: March 2022

Abstract
Oxidation of benzylic sp3 C–H bonds smoothly proceeded at ambient temperature under blue LED (465 nm) photo-irradiation using sulfur-containing tetracyclic compounds as photocatalysts. The use of 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) as a co-solvent was the key to success: various toluene derivatives were selectively oxidized to substituted benzaldehydes without over-oxidation. Preliminary mechanism studies were undertaken, including electron spin resonance (ESR) spectroscopy analyses.
Type, Intensity, and Duration of Exercise as Regulator of Gut Microbiome Profile
Authors: Suryani Dini , Subhan Alfaqih Muhammad , Gunadi Julia Windi , Sylviana Nova , Goenawan Hanna , Megantara Imam , Lesmana Ronny 
Published: March 2022

Abstract
Gut microbiome profile is related to individual health. In metabolic syndrome, there is a change in the gut microbiome profile, indicated by an increase in the ratio of Firmicutes to Bacteroidetes. Many studies have been conducted to determine the effect of exercise on modifying the gut microbiome profile. The effectiveness of exercise is influenced by its type, intensity, and duration. Aerobic training decreases splanchnic blood flow and shortens intestinal transit time. High-intensity exercise improves mitochondrial function and increases the essential bacteria in lactate metabolism and urease production. Meanwhile, exercise duration affects the hypothalamic-pituitary-adrenal axis. All of these mechanisms are related to each other in producing the effect of exercise on the gut microbiome profile.
Persistent COVID and a Return to Sport
Authors: Giusto Elisa , Asplund Chad A. 
Published: March 2022

Abstract
Coronavirus disease (COVID) has become a global pandemic that has widely impacted athletes at all levels of competition. For many athletes infected with COVID, the course is mild or asymptomatic, and most athletes are able to return to play in a matter of weeks. However, 10% to 15% of people infected with COVID will go on to have prolonged COVID symptoms that last for weeks to months and impact their ability to function and exercise. Not much is known about why certain people become “COVID long-haulers,” nor are there any predictive tools to predetermine who may have prolonged symptoms. However, many athletes will suffer from prolonged symptoms that may require further evaluation and may prolong their return to exercise, training, and competition. The purpose of this article is to discuss a framework in which sports medicine and primary care physicians can use to evaluate COVID long-haulers and help them return to sport.