bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pre-operative magnetic resonance imaging can predict prostate cancer with risk for positive surgical margins
Authors: Quentin M. , Schimmöller L. , Ullrich T. , Valentin B. , Demetrescu D. , Al-Monajjed R. , Mally D. , Esposito I. , Albers P. , Antoch G. , Arsov C. 
Published: May 2022

Abstract
Purpose
Analysis of patients with pre-operative 3 T multiparametric prostate MRI (mpMRI) to determine reliable MRI-based risk predictors of patients at risk for positive surgical margins (PSM) in robotic assisted radical prostatectomy (RPE).

Methods
Consecutive patients with 3 T mpMRI and subsequent RPE from 01/2015 to 12/2018 were retrospectively included. Patients were compared regarding clinical and MRI related parameters such as length of capsular tumor contact (LCC) and distance to the membranous urethra (UD).

Results
Forty-nine of 179 patients (27%) had PSM in 70 different localizations, with the majority located at the capsule (57%, 40/70), mostly apical and/or posterior. The second most often PSM occurred at the apical urethra (22%, 15/70). PCA was visible on mpMRI at the localization of PSM in 93% at the capsule and in 80% at the urethra. PSA, PI-RADS classification, extraprostatic extension (EPE), and seminal vesicles infiltration (SVI) on MRI were significantly higher / more frequent in patients with PSM. LCC (AUC 0.710), EPE (AUC 0.693), and UD (1-AUC 0.673) predicted PSM (overall). An UD of ≤ 3.5 mm showed the highest accuracy of 95% (J = 0.946) for PSM at the urethra and a LCC of ≥ 22.5 mm with 77% (J = 0.378) for PSM at the capsule.

Conclusion
PSM occurred mostly in the apex and/or posteriorly at the capsule or at the apical urethra. LCC was the best MRI predictor for PSM at the capsule and UD for tumors with PSM at the apical urethra. Using these MRI parameters readers might pre-operatively determine PCA localizations at risk for PSM.
Darstellung der eosinophilen Fasziitis in Ultraschall und MRT (Magnetresonanztomographie): ein Fallbericht
Authors: Gerritzen Nicolas , Ziob Jana , Brossart Peter , Schäfer Valentin S. 
Published: May 2022

ZusammenfassungDie eosinophile Fasziitis (EF, auch Shulman-Syndrom) ist eine seltene Erkrankung des Bindegewebes mit entzündlicher Verdickung der Faszien sowie Schwellung und Verhärtung der Haut. Betroffen sind v. a. die distalen Extremitäten. Typische klinische Befunde stellen eine lokalisierte Schwellung und Verhärtung der Haut sowie das Groove-Sign (deutsch: Rillenzeichen/negatives Venenzeichen/Matratzenphänomen) dar. Der Goldstandard für die Diagnosesicherung ist bisher der bioptische Nachweis entzündlich verdickter Faszien. In der Literatur wird alternativ die Diagnosesicherung durch MRT-Bildgebung diskutiert. Wir berichten über einen Fall von asymmetrischer EF bei einem 54 Jahre alten, männlichen Deutschen. Die Vorstellung erfolgte mit schmerzhafter Verhärtung im Bereich des rechten Unterarms sowie charakteristischem Groove-Sign und einer Bewegungseinschränkung der rechten Hand. Im Blutbild zeigte sich eine Eosinophilie mit 0,57 G/l bzw. 9,6 % (norm. 0,05–0,5 G/l und 0,5–5,5 %), ANAs und ENAs waren negativ. Die Diagnosesicherung erfolgte histologisch, zusätzlich konnten wir verdickte Faszien sowohl im MRT als auch in der Sonographie nachweisen. Im Verlauf manifestierte sich die EF auch am linken Malleolus lateralis. Die Therapie erfolgte mit Prednisolon und Methotrexat.
Improper case
Authors: Poole Ethan 
Published: May 2022

AbstractThis paper argues that case assignment is impossible in configurations that parallel generalized improper-movement configurations. Thus, like improper movement, there is “improper case.” The empirical motivation comes from (i) the interaction between case and movement and (ii) crossclausal case assignment in Finnish. I propose that improper case is ruled out by theBan on Improper Case: a DP in [Spec, XP] cannot establish a dependent-case relationship with a lower DP across YP if Y is higher than X in the functional sequence. I show that this constraint falls under a strong version of theWilliams Cycle(Williams 1974, 2003, 2013; van Riemsdijk and Williams 1981) and is derived under Williams’s (2003, 2013) analysis of embedding.
Family Conflict and the Use of Conventional and Electronic Cigarettes in Adolescence: the Role of Impulsivity Traits
Authors: Eslava D. , Martínez-Vispo C. , Villanueva-Blasco V. J. , Errasti-Pérez J. M. , Al-Halabí S. 
Published: May 2022

AbstractAdolescents’ use of tobacco is a worldwide problem due to the negative consequences on their physical and psychosocial development. One contextual variable related to tobacco use is family conflict. Previous research has suggested that the relationship between family conflict and tobacco use could be mediated by personality traits. The aim of this study is to examine the direct and indirect effects of family conflict on tobacco use (conventional and electronic cigarettes) through specific impulsivity constructs. The sample comprised 879 adolescents (56.4% male; M(SD)age = 14.25 (1.88) years). Multiple mediational analysis showed that there was no significant direct effect between family conflict and tobacco use; however, an indirect effect was found between family conflict and conventional cigarette use through sensation seeking and premeditation. With electronic cigarettes, a significant indirect effect was found via sensation seeking. These findings have implications in terms of prevention and treatment of tobacco use during adolescence.
Consequences of platforms' remuneration models for digital content: initial evidence and a research agenda for streaming services
Authors: Meyn Janek , Kandziora Michael , Albers Sönke , Clement Michel 
Published: May 2022

AbstractNowadays, platforms in many industries offer content for a (monthly) flat rate (e.g., music streaming). While flat rates are efficient in reducing transaction costs for administering customers, platforms’ rules for remunerating content right holders are crucial for royalty allocation and, as a result, heavily discussed in several industries. The music industry’s business practices could be on the verge of their next disruption. There is an ongoing heated debate with respect to how the income of flat rates through streaming services should be allocated to right holders (labels and artists). This research investigates aspects of the supply and demand side effects as well as the resulting monetary consequences of changing the currently applied proportional-to-usage remuneration policy (pro rata) to a user-centric policy. Using individual-level data from 3,326 participants and data from Spotify’s API, we empirically quantify the monetary consequences of this change for the music industry. Depending on the remuneration system, we find a substantial reallocation of nearly 170 million € per year at Spotify. We discuss demand and supply-side consequences that may change the way music is currently produced and consumed. We conclude with a research agenda on the impact of business conventions for users, platforms, and artists in the music streaming industry.
Evaluation of the mechanical properties and deformability of metal-based composite sheets made of thin stainless-steel sheets and carbon fiber reinforced plastics
Authors: Shibuya Yuki , Zhang Jingwei , Sato Yuji , Yanagimoto Jun 
Published: May 2022

AbstractUltra-lightweight sheets with excellent deformability are required for the development of new air vehicles, as well as greener conventional vehicles. Carbon fiber reinforced plastic (CFRP) has a high specific rigidity and strength but is too expensive to be used in general machine parts. Using CFRP enhances the properties of the material itself. Furthermore, developing the usage of the material also makes the mechanical properties higher. The purpose of this paper is to combine both methods and produce a material with better rigidity and deformability. The new structure was proposed considering the moment of inertia of area. This structure was excellent not only in terms of rigidity but also in the moldability of the core. In addition, the effects of the structure dimensions on the moldability, bonding strength and flexural rigidity were determined using finite element (FE) analysis and experiments. By comparing the results of the FE analysis conducted under pure bending conditions with three-point bending experiment, it was found that the FE analysis of pure bending fails to predict the three-point bending stiffness because the shear stress has a significant effect on the experimental measurements. By modifying the model from pure bending to three-point bending, the experimental results were well reproduced by the 3D FE analysis.
Paleoclimatic and paleoenvironmental reconstructions based on the small vertebrates from the Middle Paleolithic of Hohle Fels Cave, SW Germany
Authors: Luzi Elisa , Blanco-Lapaz Àngel , Rhodes Sara E. , Conard Nicholas J. 
Published: May 2022

AbstractIn this paper, we analyse the fish and small mammal assemblages from the Middle Paleolithic horizons of Hohle Fels Cave to reconstruct the paleoclimatic and paleoenvironmental conditions faced by the Neanderthal groups who occupied the site. The fish assemblage indicates that the freshwater ecosystem around this site was characterized by a pre-mountain river system with the presence of permanent, oxygen-rich, and cold running waters. The results of the Habitat Weighting Method and the Bioclimatic Model applied to the small mammal assemblage, coupled with the new dates obtained for the Archaeological Horizon (AH) IX, allow us to identify two different climatic phases. One phase (AH X-XII) is more temperate possibly corresponding to the end of Marine Isotope Stage (MIS) 5; the other (AH VI-IX) is colder and more arid corresponding to the end of MIS 4 through the beginning of MIS 3. Open environments with a relatively stable forest component dominated the landscape during this part of the Middle Paleolithic. These two climatic phases appear to correspond to different levels of occupational intensity by Neanderthals, with higher occupational intensity during mild climatic periods and lower intensity during cold, arid periods. Our climatic reconstruction and recent absolute dating, together with the recovery of a complete leaf point near the top of AH X, have important implications for the cultural stratigraphy and cultural chronology of the region. Archaeologist have traditionally viewed leaf points as key artefacts of the Blattspitzengruppe, a cultural complex attributed to the end of Middle Paleolithic; however, this stratigraphic, climatic, and chronological context indicates the need to revise this interpretation.
Exosome-related protein CRABP2 is upregulated in ovarian carcinoma and enhances cell proliferation
Authors: Li Ning , Lin Guocui , Zhang Ying , Zhang Qingyu , Zhang Haitao 
Published: May 2022

AbstractOvarian cancer is the most lethal cancer among women worldwide. Early diagnosis of ovarian cancer is a considerable challenge for gynecological oncologists. The exosome is a new emerging biomarker pool for cancer. Herein, we apply integrative transcriptome analysis to discover a new exosome biomarker for the diagnosis of ovarian carcinoma. We found 2316 differentially expressed genes (DEGs), among which were 431 DEGs that coded exosome proteins. We demonstrated three potential biomarkers—CRABP2, SPP1, and TNFAIP6, which are higher in ovarian cancer and associated with poor prognosis. According to receiver operating characteristic (ROC) curve analysis, CRABP2 performs better than the currently used biomarker CA125 in the diagnosis of ovarian cancer. CRABP2 level significantly elevates as the malignant property increases. We further confirmed that CRABP2 is upregulated in clinical tumor tissues of ovarian cancer patients as the malignant levels increase. CRABP2 can be detected and upregulated in the exosome in ovarian cancer patient serum samples rather than in healthy controls. GSEA revealed that high expression of CRABP2 was positively correlated with mitochondria oxidative phosphorylation pathway. At the same time, overexpression of CRABP2 can upregulate oxidative metabolism-related genes such as CYP4A11 and promote cell proliferation. Our findings based on CRABP2 could advance current practice in diagnosing and treating ovarian cancer.
Terug naar het normaal
Authors: Mulders Peter F.A. 
Published: May 2022

SamenvattingAlhier het abstractnummer van ons Tijdschrift. Niet zomaar een nummer: het zijn de abstracts die live gepresenteerd gaan worden tijdens het wetenschappelijk gedeelte van de voorjaarsvergadering van de NVU in Arnhem. Terug naar het normaal. Ondanks het feit dat de digitale voordrachten niet slecht gingen, is het natuurlijk veel beter om live reflectie te krijgen op je wetenschappelijk werk.
Abstracts voorjaarsvergadering NVU, 19 en 20 mei 2022
Authors:   Bohn Stafleu van Loghum
Published: May 2022

SamenvattingBariatrische ingrepen zoals gastric sleeve (GS) en Rouxen-Y gastric bypass (RYGB) beïnvloeden de vochtinname en het metabolisme van de patiënt en hiermee de kans op niersteenlijden. RYGB verhoogt de incidentie van niersteenlijden, GS doet dit echter niet. Meest waarschijnlijke oorzaak is de grotere metabole ontregeling (enterische hyperoxalurie) die plaatsvindt bij RYGB. Doel van deze studie is antwoord te vinden op de vraag: Is het nuttig om bij patiënten met een niersteenverleden preoperatieve metabole profilering te doen om de juiste bariatrische ingreep te kiezen en zo de kans op nieuwe stenen te verkleinen?
Online group streaming feature selection using entropy-based uncertainty measures for fuzzy neighborhood rough sets
Authors: Xu Jiucheng , Sun Yuanhao , Qu Kanglin , Meng Xiangru , Hou Qinchen 
Published: May 2022

AbstractOnline group streaming feature selection, as an essential online processing method, can deal with dynamic feature selection tasks by considering the original group structure information of the features. Due to the fuzziness and uncertainty of the feature stream, some existing methods are unstable and yield low predictive accuracy. To address these issues, this paper presents a novel online group streaming feature selection method (FNE-OGSFS) using fuzzy neighborhood entropy-based uncertainty measures. First, a separability measure integrating the dependency degree with the coincidence degree is proposed and introduced into the fuzzy neighborhood rough sets model to define a new fuzzy neighborhood entropy. Second, inspired by both algebra and information views, some fuzzy neighborhood entropy-based uncertainty measures are investigated and some properties are derived. Furthermore, the optimal features in the group are selected to flow into the feature space according to the significance of features, and the features with interactions are left. Then, all selected features are re-evaluated by the Lasso model to discard the redundant features. Finally, an online group streaming feature selection algorithm is designed. Experimental results compared with eight representative methods on thirteen datasets show that FNE-OGSFS can achieve better comprehensive performance.
Darwinian Grandparenting Redux: a Pre-registered Replication and Extension
Authors: Pearson Samuel , von Hippel William 
Published: May 2022

AbstractMothers’ fathers consistently invest more in their grandchildren than fathers’ mothers. This pattern was explained by Laham et al. in Personality and Social Psychology Bulletin , 31(1), 63-72. (2005) via the preferential investment hypothesis—the idea that fathers’ mothers invest less in grandchildren than mothers’ fathers because the former typically have more certain alternate investment outlets available. In two studies of prolific workers (combined N = 4086), we first failed to replicate the findings of Laham et al. and then successfully replicated them. In the combined sample, mothers’ fathers received more positive ratings than fathers’ mothers when participants had cousins through fathers’ sisters, but this difference between grandparents disappeared when participants did not have cousins through fathers’ sisters. We also found that people spent more time with their maternal and paternal grandparents to the degree that they were not maternal grandparents to someone else, which mediated the closer feelings.
Call Me Daddy: How Long-term Desirability Is Influenced by Intention for Fatherhood
Authors: Anderson Ryan C. , Surbey Michele K. 
Published: May 2022

AbstractOne of the most important decisions an individual can make involves investing in a mating relationship. For women, the process of mate selection can be time-intensive and fraught with costs and dangers. However, these risks can be minimised by attending to relevant social information and modelling the mate choices of others. The propensity of imitating another’s mate choices is referred to as mate copying. Most research has focused on this behaviour in non-humans, but evidence of its existence in humans is emerging. The current study sought to determine conditions that modify a man’s desirability. The present study examined 267 women’s evaluations of men depicted in silhouetted images who varied in terms of their intentions for fatherhood and relationship history. Results showed that a man’s desirability as a long term mate was enhanced if he wished to become a father, and/or if he had a previous relationship experience, indicating he had been formerly chosen or preferred. These findings add to the existing body of knowledge on mate copying and attention to social information by demonstrating how women incorporate social learning and innate evolutionary predispositions to facilitate decision-making and behaviour relating to mate selection.
Automatic location and semantic labeling of landmarks on 3D human body models
Authors: Luo Shan , Zhang Qitong , Feng Jieqing 
Published: May 2022

AbstractLandmarks on human body models are of great significance for applications such as digital anthropometry and clothing design. The diversity of pose and shape of human body models and the semantic gap make landmarking a challenging problem. In this paper, a learning-based method is proposed to locate landmarks on human body models by analyzing the relationship between geometric descriptors and semantic labels of landmarks. A shape alignment algorithm is proposed to align human body models to break symmetric ambiguity. A symmetry-aware descriptor is proposed based on the structure of the human body models, which is robust to both pose and shape variations in human body models. An AdaBoost regression algorithm is adopted to establish the correspondence between several descriptors and semantic labels of the landmarks. Quantitative and qualitative analyses and comparisons show that the proposed method can obtain more accurate landmarks and distinguish symmetrical landmarks semantically. Additionally, a dataset of landmarked human body models is also provided, containing 271 human body models collected from current human body datasets; each model has 17 landmarks labeled manually.
A comparison of the spatial heterogeneities of surface fluxes simulated by INLAND model with observations at a valley and a nearby plateau stations in Central Amazon Forest
Authors: Broedel Elisângela , von Randow Celso , Cuartas Luz Adriana , Satyamurty Prakki , de Araújo Alessandro Carioca , Cândido Luiz Antônio , Tomasella Javier , Nobre Antônio Donato , Tourigny Etienne 
Published: May 2022

AbstractAn improved version of the Integrated Land Surface Model (INLAND), incorporating the physical, ecological and hydrological parameters and processes pertaining to two subclasses of tropical forest in the central Amazon basin, a poorly drained flat plateau and a well-drained adjacent broad valley, is used to simulate the hydrological, energy and CO2fluxes. The model is forced with observed meteorological data. The experimental output data from the model runs are compared with observational data at the two locations. The seasonal variabilities of water table depth at the valley site and the soil moisture at the plateau site are satisfactorily simulated. The two locations exhibit large differences in energy, carbon and water fluxes, both in the simulations and in the observations. Results validate the INLAND model and indicate the need for incorporating sub-grid scale variability in the relief, soil type and vegetation type attributes to improve the representation of the Amazonian ecosystems in land-surface models.
Psychometric Properties of the Danish Version of the Questionnaire Professionals’ Attitudes towards Addressing Sexual Health (PA-SH-D)
Authors: Elnegaard Caroline M. , Christensen Jan , Thuesen Jette , Areskoug-Josefsson Kristina , Gerbild Helle N. 
Published: May 2022

Abstract

Background
Health professionals’ attitudes towards addressing sexual health are important to promote patients’ sexual health. Therefore, measurement of health professionals’ attitudes towards addressing sexual health is essential.

Aim
This study aimed to adapt the questionnaire Students’ Attitudes towards Addressing Sexual Health (SA-SH-D) to health professionals working with rehabilitation in Danish municipalities and evaluated psychometric properties of the adapted questionnaire: The Danish Version of the Professionals’ Attitudes towards Addressing Sexual Health (PA-SH-D).

Methods
The SA-SH-D was adapted to PA-SH-D and a face validity evaluation focusing on phrasing, functionality, perception and relevance was done. In a pilot study, the PA-SH-D was answered by health professionals and internal consistency reliability and floor and ceiling effects were evaluated.

Outcomes
Face validity included phrasing, functionality, perception and relevance of the items in PA-SH-D, internal consistency with Cronbach's alpha in the total scale and floor and ceiling effects.

Results
Face validity of the PA-SH-D was acceptable. The sample size was 52 health professionals working with rehabilitation, the internal consistency reliability (Cronbach's alpha: 0.89 [lower confidence interval {CI}: 0.85]) and floor and ceiling effects (0.0%–13.7%) of the PA-SH-D were acceptable.

Clinical translation
As sexual health is important in human quality of life, the validation of the PA-SH-D is highly valuable as it evaluates health professionals’ attitudes towards addressing sexual health, and thereby is able to measure the need for education and training in sexual health and detect changes in attitudes following an educational intervention.

Strengths and limitations
Strengths were that the PA-SH-D measures both attitudes and competences and covered a need in clinical practice. The recruitment was broad and we used the work of others to orient this work. Limitations were that this study covered a preliminary psychometric evaluation and a thorough evaluation covering other aspects of psychometry should be done. We used both paper-based and online-based survey which possibly could cause bias. The study had a relatively small sample size. Comparing health professionals to students can be seen as both a limitation and a strength.

Conclusion
The results in face validity and internal consistency reliability indicate usefulness of the PA-SH-D to measure health professionals’ attitudes towards addressing sexual health. Further evaluation of psychometric properties of the PA-SH-D is recommended.