bluuebunny/crossref_metadata_2025_split huggingface dataset:
When is sociality congruent with self‐care?
Authors: Ratner Rebecca K. , Kim Nicole You Jeung , Wu Yuechen 
Published: November 2022

AbstractKumar and Epley (2023) argue that people underinvest in spending time, effort, and money on other people, and that consumers' own well‐being would improve from increased “sociality.” We pose two questions to enhance understanding of the relationship between sociality and efforts to benefit one's own well‐being: (1) when will other‐oriented consumption promote versus hinder consumers' own well‐being, and (2) what leads consumers to embrace versus forego efforts to improve their well‐being (i.e., self‐care) that does not involve sociality? We propose that the degree to which the consumer is concerned about incorporating others' preferences, the magnitude of resources involved, and the temporal dynamics of consumption will be relevant factors in addressing these two questions. Future research to explore the proposed three factors and other factors will be important for consumers who seek to improve their well‐being as well as marketers who seek to promote it.
Attention‐deficit/hyperactivity disorder and white matter microstructure: The importance of dimensional analyses and sex differences
Authors: Jones Scott A. , Nagel Bonnie J. , Nigg Joel T. , Karalunas Sarah L. 
Published: November 2022

AbstractBackgroundAttention‐deficit/hyperactive disorder (ADHD) has substantial heterogeneity in clinical presentation. A potentially important clue may be variation in brain microstructure. Using fractional anisotropy (FA), previous studies have produced equivocal results in relation to ADHD. This may be due to insufficient consideration of possible sex differences and ADHD's multi‐componential nature.MethodsUsing whole‐brain analyses, we investigated the association between FA and both ADHD diagnosis and ADHD symptom domains in a well‐characterized, ADHD (n = 234; 32% female youth) and non‐ADHD (n = 177; 52% female youth), case‐control cohort (ages 7–12). Sex‐specific effects were tested.ResultsNo ADHD group differences were found using categorical assessment of ADHD without consideration of moderators. However, dimensional analyses found total symptoms were associated with higher FA in the superior corona radiata. Further, inattention symptoms were associated with higher FA in the corpus callosum and ansa lenticularis, and lower FA in the superior longitudinal fasciculus (SLF), after controlling for overlap with hyperactivity‐impulsivity. Hyperactivity‐impulsivity symptoms were associated with higher FA in the SLF, and lower FA in the superior cerebellar peduncles, after control for overlap with inattention. Meanwhile, both categorical and dimensional analyses revealed ADHD‐by‐sex interactions (voxel‐wise p < .01). Girls with ADHD had higher FA, but boys with ADHD had lower FA (or no effect), compared to their same‐sex peers, in the bilateral anterior corona radiata. Further, higher ADHD symptom severity was associated with higher FA in girls, but lower FA in boys, in the anterior and posterior corona radiata and cerebral peduncles.ConclusionsADHD symptom domains appear to be differentially related to white matter microstructure, highlighting the multi‐componential nature of the disorder. Further, sex differences will be crucial to consider in future studies characterizing ADHD‐related differences in white matter microstructure.
Huế dental students’ use and perception of an online dental learning platform: A pilot study
Authors: Li Alice Z. , Khan Mariam , Nguyen Nicholas T. , Breitman Leela , Luca Jennifer , Van Doren Emily , Gia Kieu Ngan Nguyen , Thị Hoàng Yến Nguyễn , Dang Khoa , Tan Tai Tran , Taylor Russell H. 
Published: November 2022

AbstractPurpose/ObjectivesOnline educational materials are growing in use, and dental students worldwide can benefit from higher quality and more accessible online supplemental resources. This study was created to evaluate the learning resources non‐English speaking dental students desire and to pilot My Dental Key (MDK), an English, evidence‐based, online dental educational platform.MethodsThird to sixth year dental students at the Huế University of Medicine and Pharmacy were asked to pilot MDK over a 5‐week period and were invited to answer three surveys throughout the study. A preliminary survey was given to gauge the participants’ (n= 209) preferences regarding the use of English‐based dental educational resources. Participants (n= 58) completed a presurvey prior to accessing MDK. After the 5‐week period, participants (n= 38) were given a postsurvey to evaluate the platform's effectiveness as a supplemental educational resource.ResultsOverall, we found that: (1) students desire credible online supplemental resources in addition to current resources provided by their school, (2) the multimodal content that MDK provides is a strength that bridges language barriers (3) participants perceived that the content on MDK would help them in class and when treating patients.ConclusionsImproving the quality of online supplemental dental resources will have the capability to progress the current educational landscape, and further resources should be created to best serve the global dental community.
Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle‐based vaccine platform, for efficient viral antigen delivery
Authors: Hu Kai , Palmieri Elena , Samnuan Karnyart , Ricchetti Beatrice , Oldrini Davide , McKay Paul F. , Wu Guanghui , Thorne Leigh , Fooks Anthony R. , McElhinney Lorraine M. , Goharriz Hooman , Golding Megan , Shattock Robin J. , Micoli Francesca 
Published: November 2022

AbstractVaccine platforms enable fast development, testing, and manufacture of more affordable vaccines. Here, we evaluated Generalized Modules for Membrane Antigens (GMMA), outer membrane vesicles (OMVs) generated by genetically modified Gram‐negative bacteria, as a vaccine platform for viral pathogens. Influenza A virus hemagglutinin (HA), either physically mixed with GMMA (HA+STmGMMA mix), or covalently linked to GMMA surface (HA‐STmGMMA conjugate), significantly increased antigen‐specific humoral and cellular responses, with HA‐STmGMMA conjugate inducing further enhancement than HA+STmGMMA mix. HA‐STmGMMA conjugate protected mice from lethal challenge. The versatility for this platform was confirmed by conjugation of rabies glycoprotein (RABVG) onto GMMA through the same method. RABVG+STmGMMA mix and RABVG‐STmGMMA conjugate exhibited similar humoral and cellular response patterns and protection efficacy as the HA formulations, indicating relatively consistent responses for different vaccines based on the GMMA platform. Comparing to soluble protein, GMMA was more efficiently taken up in vivo and exhibited a B‐cell preferential uptake in the draining lymph nodes (LNs). Together, GMMA enhances immunity against viral antigens, and the platform works well with different antigens while retaining similar immunomodulatory patterns. The findings of our study imply the great potential of GMMA‐based vaccine platform also against viral infectious diseases.
Pathogenesis and histological changes of nephropathy associated with COVID‐19
Authors: Lin Lirong , Deng Junhui , Tan Wei , Li Jie , Wu Zhifeng , Zheng Luquan , Yang Jurong 
Published: November 2022

AbstractCoronavirus disease 2019 (COVID‐19) can cause damage to multiple organ, not only to the lungs, but also to the kidneys. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can cause acute and chronic kidney disease through direct viral infection, indirect injury, and vaccination‐related injury. Like lung injury, kidney injury is also an important aspect affecting the severity and prognosis of SARS‐CoV‐2. This article summarizes the pathogenesis, pathological manifestations, and clinical features of SARS‐CoV‐2 direct or indirect renal injury. Including direct injury, indirect injury, special comorbidities (receiving kidney transplantation and chronic kidney disease), and vaccine‐related renal injury, and exploring the possible therapeutic effect of anti‐SARS‐CoV‐2 therapy on renal injury. The purpose is to provide reference for understanding COVID‐19‐related renal injury, guiding clinical and pathological diagnosis and treatment, and evaluating prognosis.
Performance of the Weather Research and Forecasting model in simulating climate over northern Asia
Authors: Bai Rui , Sun Jianqi , Yu Entao , Yu Shui 
Published: November 2022

AbstractHigh‐resolution simulation is important for understanding climate change and its impact over regions with complex terrain. Northern Asia (NA) is such a region and sensitive to global warming. However, the performance of the regional model over NA is still unclear. In this study, we conducted a two‐decade‐long high‐resolution (25 km) simulation over NA using the Weather Research and Forecasting (WRF) model forced by the ERA‐Interim reanalysis and then evaluated the performance of WRF against the observations. The results show that the WRF simulation, set up with selections of the physical schemes, can reasonably reproduce the spatial and temporal features of surface air temperature and precipitation over NA. In addition, the WRF simulation can add more regional details on the climate features than the ERA‐Interim data, especially over the NA regions with complex terrain. The spatial‐pattern correlation coefficient of summer precipitation over NA between the WRF simulation and observations is higher than that of the ERA‐Interim data. WRF can reasonably reproduce the annual cycles of precipitation. Moreover, the observed year‐to‐year variations in summer surface air temperature and precipitation over most NA subregions could be generally captured by the WRF. In conclusion, although systemic model bias still exists, the evaluations in this study indicate that WRF shows reasonable performance in a high‐resolution simulation of climate over NA, consequently providing a scientific basis for future simulation studies over the region.
Pre‐heated blades for harvesting baby‐leaves reduce the risk of Escherichia coli internalization in leaves
Authors: Guerra Simona , Michelotti Martina , Signorini Sofia , Rossi Giuseppe , Procopio Tiziana , Truschi Stefania , Lenzi Anna , Marvasi Massimiliano 
Published: November 2022

AbstractBACKGROUNDPathogenic enterobacteria can travel through the plant vascular bundles by penetrating from cuts and persisting into ready‐to‐eat leafy greens. Because the cutting site is the main point of entrance and uptake, we tested how different cutting strategies can reduce bacterial internalization in leaves. Horizontal cuts at the base of the leaves were performed with two different types of tools: the first with a scalpel (by pulling the blade) and the second with a scissor‐action that has blades that cuts by gliding against a thicker blade. Scissor‐action generally makes closer border cuts. Blades of both types of tools have worked at 25 °C and 200 °C. The present study aimed to determine how these different types of cuts and temperatures affected bacterial uptake in leaves. Experiments were repeated on different plant genotypes and at different wilting stages.RESULTSOur findings showed that cutting baby‐leaves with a scissor action at 200 °C significantly reduced the bacterial uptake compared to the not heated (which simulates a mechanized lettuce harvester). The most effective cutting treatments for reducing bacterial uptake were in the order: scissor 200 °C > scissor 25 °C > scalpel 200 °C > scalpel 25 °C. The scissor heated at 200 °C also prevented bacterial uptake on wilted baby‐leaves.CONCLUSIONThe findings of the present study could provide a further contribution in terms of safety during harvest and suggest that a pre‐heated blade supports safety during harvest of leafy greens. © 2022 Society of Chemical Industry.
Realizing High‐Power Laser Lighting: Artfully Importing Micrometer BN into Ce: GdYAG Phosphor‐in‐Glass Film
Authors: Wang Luhan , Liu Jiawei , Xu Li , Bao Shuyang , Wang Yu , Zhang Jiangdan , Liang Xiaojuan , Xiang Weidong 
Published: November 2022

AbstractPhosphor‐in‐glass (PiG) film has been proposed as an ideal color converter in laser diodes (LDs) lighting for its advantages of outstanding thermal conductivity (TC) and superior efficiency. Herein, yellow‐emitting Y1.31Ce0.09Gd1.6Al5O12 (Ce: GdYAG)‐PiG composite films are successfully elaborated through a practical blade‐coating approach. Systematical studies are performed on its microstructure, thermal stability, and luminescence performance pumped by LDs. Noteworthy, the highest internal quantum efficiency of film (94.2%) retains 97.1% of the raw phosphors (97%). Particularly, by further introducing micrometer BN with high TC as light scattering center to enhance heat dissipation and increase porosity, the thermal and optical properties of the sample are greatly improved. The luminescence intensity of the sample at 423 K is increased to 1.8 times that at 298 K. The thermal diffusion (TD) and TC of the sample are increased from 1.571 to 4.227 mm2 s−1 and 6.4 to 13.0 W m−1 K−1, respectively. At the same time, the maximum saturation threshold under laser irradiation of Ce: GdYAG + micrometer BN composite film is raised from 3.12 to 5.42 W mm−2 and 260.6 to 354.1 lm, respectively. The combination of excellent optical and thermal performances, coupled with facile and low‐cost synthetic strategy, could push forward the practical application in solid‐state laser lighting.
Linear Regulating of Polymer Acceptor Aggregation with Short Alkyl Chain Units Enhances All‐Polymer Solar Cells’ Efficiency
Authors: Qiu Jinjing , Liu Miao , Wang Yang , Xia Xinxin , Liu Qi , Guo Xia , Lu Xinhui , Zhang Maojie 
Published: November 2022

AbstractThe power conversion efficiency (PCE) of all‐polymer solar cells (all‐PSCs) has ascended rapidly arising from the development of polymerized small‐molecule acceptor materials. However, numerous insulating long alkyl chains, which ensure the solubility of the polymer, result in inferior aggregation and charge mobility. Herein, this study proposes a facile random copolymerization strategy of two small molecule acceptor units with different lengths of alkyl side chains and synthesizes a series of polymer acceptors PYT‐EHx, wherexis the percentage of the short alkyl chain units. The aggregation strength and charge mobility of the acceptors rise linearly with increasing the proportion of short alkyl chain units. Thus, the PYT‐EH20 reaches balanced aggregation with the star polymer donor PBDB‐T, resulting in optimal morphology, fastest carrier transport, and reduced recombination and energy loss. Consequently, the PYT‐EH20‐based device yields a 14.8% PCE, a 16% improvement over the control PYT‐EH0‐based device, accompanied by an increase in open‐circuit voltage (Voc), short‐circuit current density (Jsc), and fill factor (FF). This work demonstrates that the random copolymerization strategy with short alkyl chain insertion is an effective avenue for developing high‐performance polymer acceptors, which facilitates further advances in the efficiency of all‐PSCs.
Patient preferences and decision‐making when considering surgery for musculoskeletal disorders: A mixed methods systematic review
Authors: Healy Sarah , Dorflinger Eric , Michaleff Zoe A. , Marks Darryn 
Published: November 2022

AbstractIntroductionThe burden of Musculoskeletal disorders (MSD) is large. Surgery is an important management option but the factors that shape patients' surgical decisions are not well understood. As prior reviews have explored only single data types or conditions, a mixed methods appraisal across the musculoskeletal spectrum was undertaken.MethodsA mixed‐methods systematic, convergent segregated approach was used, with PubMed, Cumulated Index to Nursing and Allied Health Literature (CINHAL), Embase and PsycINFO searched to identify studies of adult patients' decisions about whether to undergo surgery. A narrative synthesis was conducted, with identified themes integrated across quantitative, qualitative and mixed‐methods studies.ResultsForty‐six studies were included (24 quantitative, 19 qualitative and three mixed methods), with four decision‐making themes identified (symptoms, sociodemographic and health factors, information and perceptions). Decision‐making involves a complex interaction of individual sociodemographic, health and symptom information, integrated with individual perceptions of candidacy and surgical expectations. While most studies investigated hip and knee surgery, across all included conditions, patients are more likely to favour surgery if symptoms and/or dysfunction are higher, and if perceptions of surgical candidacy and processes (outcomes, inconvenience, and risk) are favourable. Other factors including age, general health, race, financial context, professional and non‐professional communication, and information sources also impact decision‐making but exert a less consistent impact upon the propensity to prefer surgery.ConclusionPatients are more likely to choose surgery for MSD when they have higher levels of symptoms or dysfunction and positive perceptions of surgical suitability and expectations. Other factors important to individuals, have a less consistent impact upon the propensity to prefer surgery. These findings have potential to aid the efficient referral of patients to orthopaedics. More research is needed to validate these findings across the spectrum of MSD.
Untargeted GC–MS metabolomics to identify and classify bioactive compounds in Combretum platypetalum subsp. oatesii (Rolfe) Exell (Combretaceae)
Authors: Umoh Sampson D. , Bojase Gomotsang , Masesane Ishmael B. , Majinda Runner T. , Sichilongo Kwenga F. 
Published: November 2022

AbstractIntroductionCombretum platypetalum is used in traditional African healing practices against different infections. Unfortunately, no scientific knowledge of its phytochemical composition exists, except for the isolation of two compounds from the leaves. Scientific study has been limited to the leaves only, despite the applications of stems and roots in traditional medicine practice and natural product drug discovery programs.ObjectiveOmics was applied to identify and classify different volatile and semivolatile bioactive compounds in the leaf, stem, and root parts of C. platypetalum. The thermal stability of the plant constituents at 60–65°C extraction temperature by Soxhlet and maceration at room temperature on the type, class, and concentration of compounds in the leaf was further investigated.MethodA GC–MS untargeted metabolomics approach, automated deconvolution by the Automated Mass Spectral Deconvolution and Identification System (AMDIS) for GC–MS data, preprocessing by Metab R, and multivariate statistical data analysis were employed in this study.ResultsA total of 97 phytoconstituents, including 17 bioactive compounds belonging to the terpenoids, flavonoids, long‐chain fatty acids, and other unclassified structural arrangements distributed across C. platypetalum, were identified for the first time. A correlation (r = 0.782; P = 0.000) between Soxhlet and maceration extraction methods relative to resolved chromatographic peak areas of metabolites was established.ConclusionFindings corroborate the reported bio‐investigation of its leaf extracts, its traditional uses, and previous findings from the Combretum genus. The results substantiate the possible applications of C. platypetalum in natural product drug discovery and provide a guide for future investigations.
Associations of prenatal exposure to non‐steroidal anti‐inflammatory drugs with preterm birth and small for gestational age infants among women with autoimmune disorders
Authors: Delker Erin , Kelly Ann , Chambers Christina , Johnson Diana , Bandoli Gretchen 
Published: November 2022

AbstractPurposeEstimate associations between prenatal non‐steroidal anti‐inflammatory (NSAID) exposure and preterm birth and small for gestational age among women with autoimmune conditions.MethodsParticipants were enrolled in the MotherToBaby cohort and had an autoimmune disorder and singleton live birth >20 weeks gestation (n = 2007). We characterized self‐reported NSAID exposure over gestation for timing, duration, and average daily dose. Outcomes were preterm birth (i.e., <37 weeks' gestation) and small for gestational age infants (SGA; <10th percentile birthweight). We used Poisson regression to estimate associations between NSAID exposure and study outcomes adjusting for demographics, co‐use of other medications (Model 1), and disease severity at baseline (Model 2). Secondarily, we considered the role of acetaminophen use by individually matching NSAID users to controls on cumulative dose of acetaminophen exposure.ResultsOverall, 15% of women reported NSAID use in pregnancy, with most use in the first trimester. No NSAID use exposure variables were associated with risk of preterm birth. Any NSAID use was associated with 1.7 (95% CI 1.2, 2.5) times greater risk of SGA and this estimate was attenuated to 1.5 (95% CI 1.0, 2.3) after adjustment for baseline disease severity. NSAID exposure in the first trimester was most strongly associated with SGA. After matching on acetaminophen exposure, associations between any NSAID use and preterm birth and SGA were 0.9 (95% CI 0.6, 1.4) and 1.8 (95% CI 1.1, 2.9).ConclusionsNSAID use in pregnancy is associated with SGA but not preterm birth. Future research should explore mechanisms that may explain these findings. Future research must also consider alternative explanations for these associations.
The monkeypox virus: A public health challenge threatening Africa
Authors: Manirambona Emery , Musa Shuaibu Saidu , Shomuyiwa Deborah Oluwaseun , Salam Feruzi Abdu , John Okesanya Olalekan , Dinyo Daniel Garang Aluk , Haruna Usman Abubakar , Sow Alhaji Umar , Lucero‐Prisno Don Eliseo , Ezie Kengo Nathan , Samai Mohamed , Aziato Lydia 
Published: November 2022

AbstractOn 23 July 2022, the World Health Organization reported monkeypox cases in over 75 countries and, as a result, declared the virus a Public Health Emergency of International Concern (PHEIC). Despite Africa being the centre of the zoonotic disease evolution, its healthcare systems have not provided optimum attention to the problem. The African healthcare system is under the threat of a repeat of the situation that transpired during the COVID‐19 pandemonium if stringent measures are not implemented immediately. Lessons learned from the COVID‐19 pandemic should inform emergency preparedness and response from African countries. Concerted and sustainable efforts can be achieved by reviewing and redesigning strategic preparedness plans for testing and vaccination as in previous pandemics. Africa needs to drive this response with collaboration and a united response, and with the use of strategic communication and a sense of urgency. Africa should prioritise access to available vaccines and invest in systems development for local vaccine production. In this article, we argue that monkeypox virus has serious public health implications in Africa and the region.