bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eye Movements and Eating Disorders: an Exploratory Experimental Study Examining the Relationship in Young-adult Women With Subclinical Symptomatology.
Authors: Navas-León Sergio , Sánchez-Martín Milagrosa , Tajadura-Jiménez Ana , De Coster Lize , Borda-Más Mercedes , Morales Luis 
Published: February 2022

Abstract
Background: Recent research indicates that patients with anorexia (AN) show specific eye movement abnormalities such as shorter prosaccade latencies, more saccade inhibition errors, and increased rate of saccadic intrusions compared to participants without AN. However, it remains unknown whether these abnormal eye movement patterns, which may serve as potential biomarkers and endophenotypes for an early diagnosis and preventive clinical treatments, start to manifest also in people with subclinical eating disorders (ED) symptomatology. Therefore, the present study aims to investigate whether participants with subclinical ED symptomatology and control participants differ in their performance on several eye movement tasks. Methods: The sample will be recruited through convenience sampling. The Eating Disorder Examination Questionnaire (EDE-Q) will be administered as a screening tool to split the sample into participants with subclinical ED symptomatology and control participants. A fixation task, prosaccade/antisaccade task, and memory-guided task will be administered to both groups. Additionally, we will measure anxiety and premorbid intelligence as confounding variables. Analyses of variance and exploratory Pearson's correlations will be performed. Discussion: This study will be the first to elucidate the presence of specific eye movement abnormalities in participants with subclinical ED symptomatology. The results may open opportunities for developing novel diagnostic tools/therapies being helpful to the EDs research community and allied fields.
Hybridizing research and decision-making: a path toward sustainability in marine spaces
Authors: Boemare Catherine , Mosseri Elsa , Agin Grégory , Bramanti Lorenzo , Certain Raphaël , Claudet Joachim , Guizien Katell , Jabouin Coraline , Lagurgue Xavier , Lenfant Philippe , Levrel Harold , Michel Charlotte , Musard Olivier , Verdoit-Jarraya Marion 
Published: February 2022

Abstract
Projecting the combined effect of management options and the evolving climate is necessary to inform shared sustainable futures for marine activities and biodiversity. However, engaging multi-sectoral stakeholders in biodiversity-use scenarios analysis remains a challenge. Using a marine social-ecological case study, we coupled co-designed visioning narratives at the horizon 2050 with an ecosystem-based model. Our analysis revealed a mismatch between the stated vision endpoints at 2050 and the model predictions narrative objectives. However, the discussions that arose from the approach opened the way for previously unidentified transformative pathways. Hybridizing research and decision-making with iterative collaborative modelling frameworks can enhance adaptive management policies, levering paths toward sustainability.
Physarum-based Emergence Evacuation Plan
Authors: Yang Hanchao , Deng Yong , Pelusi Danilo 
Published: February 2022

Abstract
The rapid urbanization in many countries, especially in some developing countries keeps enlarging the size of cities and the hight of buildings. However, the rise of population would also increase the risk of emergence situation that need large evacuation like fire and earth quake. While many researchers aims to build evacuation and evaluation model in different situations, some researchers tried to build a guide system for quick evacuation based on monitors and other high-tech devices. This paper severs to proposed a dependence-less evacuation plan for buildings and cities by flow guidance. Physarum algorithm and user equilibrium was adopted to estimate the optimal flux in each link, and triangular fuzz number was used to handle the uncertainty in emergence situation. Two numeric example was utilized to prove the efficiency of the proposed method.
Functions and Clinical Significances of LncRNA SChLAP1 and UBE2E3 in Prostate Cancer
Authors: Jiang Wei , Xie Ruoyun , Chen Xiaobao , Huang Linjin , Zhou Junkai 
Published: February 2022

Abstract
Backgrounds:
Prostate cancer is the most common cancer in male with high morbidity and mortality. The long noncoding RNA second chromosome locus associated with prostate-1(SChLAP1) and ubiquitin conjugating enzyme(UBE2E3) have been reported to relate to prostate cancer. SCHLAP1-UBE2E3 was found to be the most frequent gene fusion in Chinese. However, the function and mechanism of SChLAP1-UBE2E3 axis in prostate cancer are not well known.
Methods
In this study, we investigated the relationship between SChLAP1 and UBE2E3 expression and development of prostate cancer in Chinese men who have undergone radical resection of prostate cancer. The effects of SChLAP1 and UBE2E3 on proliferation, migration and invasion of prostate cancer cells were respectively explored.
Results
We found that SChLAP1 and UBE2E3 were both over expressed in prostate cancer cells and tissues. There was a positive correlation between the expression of UBE2E3 and SCHLAP1. Overexpression of SChLAP1 and UBE2E3 both promoted cell proliferation. migration and invasion and inhibited apoptosis. SChLAP1 and UBE2E3 knocking down just had the opposite effects.
Conclusions
Our study proved that SChLAP1 and UBE2E3 influenced the progressive of prostate cancer and provided potential biomarkers or drug targets for prostate cancer.
Sexually Transmitted Infection and Related High-Risk Behaviors Among Female Sex Workers in Iran: Results of the National Rapid Assessment &amp; Response (RAR), 2017
Authors: Roshanfekr Payam , moftakhar Leila , Ali Delaram , Vameghi Meroe , Narouee Sakineh , soufi khodamord , SoleimanvandiAzar Neda 
Published: February 2022

Abstract
Background
Sexually transmitted infections are one of the most important public health problems and have serious consequences for female sex worker. The aim of this study was to investigate the prevalence of STIs among sex workers and to identify high-risk behaviors affecting STIs.
Methods
In this cross-sectional study, 898 women sex workers were studied in 21 provinces of Iran from October 2016 to March 2017. The required information was collected through self-report and completing a questionnaire. Simple and multiple logistic regression was used with 95% significance level. To identify risk factors for sexually transmitted diseases.
Results
The prevalence of STIs was 41.8%. Multiple logistic regression results showed that the odds of getting STIs in FSW over the age of 35was 5.6 times higher than FSWs 18–24 years (AOR = 5.65, 95% CI: 1.035, 30.90), and the odds of getting STIs in FSWs with imprisonment was 3 times higher in FSW without imprisonment (AOR = 3.00, 95% CI: 1.04, 8.62), Also odds of getting STIs in FSWs who used injectable drugs was 17.2 times higher in FSW who did not take injectable drugs (AOR = 17.21, 95% CI: 2.54, 116.59). But self-perceived risk of HIV was borderline (AOR = 3.81, 95% CI: 0.97, 14.93),
Conclusion
The findings of this study can provide evidence for designing and implementing for risk reduction interventions for FSWs.
An Innovative Hybrid Algorithm for Solving Combined Economic and Emission Dispatch Problems
Authors: Verma Pooja , Parouha Raghav Prasad 
Published: February 2022

Abstract
As environmental concerns have grown, the combined economic emission dispatch (CEED) problem has gotten a lot of attention. Both the cost of fuel and the emission pollution caused by it must be kept to a minimum. As a result, this paper presents an innovative hybrid approach (ihPSODE) for solving CEED problems. This hybrid technique incorporated novel differential evolution (nDE) and particle swarm optimization (nPSO). Where nDE introduces a new mutation approach and crossover rate (to prevent premature convergence) as well as nPSO introduces a new acceleration coefficient, inertia weight and position improve equation (to alleviate the stagnation). So as to balance among local and global search ability, after ihPSODE population evaluation, the best half individuals are determined and the rest individuals are discarded. Then, nPSO is used in the current population (to sustain exploration and exploitation) and nDE is employed in the nPSO generated population (to improve convergence accuracy). The competence of the proposed algorithms (ihPSODE, nPSO and nDE) are inspected on 23 unconstrained benchmark function and then solved 3 test system (3-, 6- and 40-unit) of economic load dispatch (ELD) and 3 test system (3-, 10- and 40-unit) of CEED problem. The experiments have denoted that the proposed algorithms show competitive results and significant performances.
Combined use of 3D printing and computer-assisted navigation in the clinical treatment of multiple maxillofacial fractures
Authors: Wang Haohong , Chi Yifan , Huang Hanxiao , Su Shiheng , Hou Jun , Xue Haowei 
Published: February 2022

Abstract
Objectives: Although computer-assisted navigation (CAN) has been widely used in the reconstruction of maxillofacial fractures, it is insufficient to provide direct guidance for surgical operations and handle multiple maxillofacial fractures due to the lack of a healthy side for reference. To address the problem above, a 3D-printed guide and head model was used in combination with CAN in this study.Materials and Methods: In this process, 26 patients were randomly selected among those with multiple fractures treated from 09/2017 to 03/2021. They were randomly divided into the experimental and control groups, with 3D-printed guides and models used in the former group. Posttreatment computed tomography, surgical time and follow-up visits were conducted at 1 week and 3 months, respectively, to compare the quality of treatment, including in terms of infection, occlusal disorder, restricted mouth opening, midline displacement, and bilateral asymmetry. The Spearman rank correlation coefficient was used for assessment.Results: According to our results, the therapeutic effect was excellent in 12 cases and satisfactory in 1 case among the 13 cases in the experimental group, while the therapeutic effect was excellent in only 7, satisfactory in 3, and unsatisfactory in 3 cases in the control group.Conclusions: According to our analysis, the combined use of CAN and 3D printing significantly improved the treatment results of double-sided maxillofacial fractures (rs=0.448, P<0.05). The surgical time of the experimental group was significantly shorter than that of the control group (Z=-2.083, P<0.05).Clinical Relevance: This study broadens our understanding of the treatment of multiple maxillofacial fractures. The combined use of 3D printing technology and CAN can effectively shorten the operation time and achieve a better therapeutic effect.
Tongue muscle is protected from dystrophic changes in the Duchenne Muscular Dystrophy Rat
Authors: Yamanouchi Keitaro , Tanaka Yukie , Ikeda Masanari , Kato Shizuka , Chambers James , Matsuwaki Takashi , Uchida Kazuyuki 
Published: February 2022

Abstract
Background: Duchenne muscular dystrophy (DMD) is an X-linked muscle disease caused by a complete lack of dystrophin, which stabilizes the plasma membrane of myofibers. The orofacial function is affected in an advanced stage of DMD and this often leads to an eating disorder such as dysphagia. Dysphagia is caused by multiple etiologies including decreased mastication and swallowing. Therefore, preventing the functional declines of mastication and swallowing in DMD is important to improve the patient's quality of life. In the present study, using a rat model of DMD we generated previously, we performed analyses on masseter and tongue muscles, both are required for proper eating function. Methods: Age-related changes of masseter and tongue muscle of DMD rats were analyzed morphometrically, histologically, and immunohistochemically. Also, gene expressions of p16, a marker of cellular senescence, and utrophin, a functional analog of dystrophin, were examined. Results: The masseter muscle of DMD rats showed progressive dystrophic changes as observed in their hindlimb muscle accompanied by increased expression of p16. On the other hand, the tongue of DMD rats showed macroglossia due to hypertrophy of myofibers without degenerative/necrotic changes. Proliferative activity was preserved in the satellite cells from the tongue muscle but was perturbed severely in those from the masseter muscle. While utrophin expression was increased in the masseter muscle of DMD rats compared to WT rats, probably due to compensatory mechanism, its expression level in the tongue muscle was comparable between WT and DMD rats and was similar to that in the masseter muscle of DMD rats. Conclusions: The tongue muscle of the rat is protected from degenerative/necrotic dystrophic changes despite the absence of dystrophin.
Arabinogalactan prevented APAP-induced acute liver injury by regulating the intestinal flora in mice
Authors: Wang Dongxu , Zhou Shengxue , Wang Xiuying 
Published: February 2022

Abstract
Background: This study aimed to explore the mechanism by which arabinogalactan (AG) inhibited N-acetyl-para-aminophenol (APAP)-induced acute liver injury in mice. The balance of the mouse intestinal flora and the relationship between AG treatment and the PI3K/AKT and NF-κB signaling pathways were evaluated to confirm a liver-gut interaction. Methods: Mice were administered 2 different doses of AG (150 or 300 mg/kg body weight) by gavage for 7 days and liver injury was induced by a single injection of APAP (250 m/kg). Hematoxylin-eosin staining, terminal deoxynucleotidyl transferase dUTP nick-end labeling, and Hoechst 33258 fluorescence staining of liver tissue were used to analyze liver damage. Western blots were used to evaluate expression of proteins related to PI3K/AKT and NF-κB signaling pathways, and changes in the hierarchical structure of the intestinal flora were determined. Results: AG pretreatment increased the proportion of Lactobacillus and decreased the abundance of species from norank_o_Clostridiaceae and Prevotella in mouse feces compared with APAP-only treated mice. AG pretreatment reversed glutathione depletion and CYP2E1 overexpression, reduced the production of malondialdehyde and 4-hydroxynonenal, and decreased the levels of alanine aminotransferase, aspartate aminotransferase, tumor necrosis factor-α and interleukin-1β compared with the APAP-only treated mice. The levels of proteins related to the PI3K/AKT signaling pathway were similar between the AG and control groups. AG pretreatment significantly reduced APAP-induced hepatocyte apoptosis and necrosis and inflammatory infiltration into the liver. Conclusion: PI3K/AKT pathway-mediated BAX expression and the NF-κB signaling cascade were inhibited by AG. AG protected the intestinal flora composition, which subsequently suppressed oxidative stress in the liver, improved the inflammatory response, and reduced hepatocyte apoptosis and necrosis.
Universal health coverage of five essential health services in mothers before and after the Haiti 2010 earthquake: a retrospective cohort study using difference-in-difference
Authors: Hirose Naoki , Chen Sanmei , Shiba Koichiro , Patil Crystal L , Rahman MD Moshiur , Shimpuku Yoko 
Published: February 2022

Abstract
Background
In January 2010, Haiti was hit by a 7.0-magnitude earthquake. The impact of the earthquake on Universal Health Coverage in mothers remains unclear. This study explores the association between the 2010 Haiti earthquake and access to the five quality essential health services among women who gave birth in the two years before and after the earthquake.
Methods
From the Sixth Demographic and Health Survey in Haiti, we extracted data for women aged 15–49 who had reported a live birth in the two years before and after the 2010 Haiti earthquake. We used difference-in-difference analyses for antenatal care, delivery care, and vaccination and multivariate logistic regression analyses for family planning and malaria prevention to assess the impact of the acute physical damage of the earthquake on these mothers’ access to quality essential health services.
Results
Mothers who had not suffered acute physical damage were more likely to live in rural areas and had less education and household wealth. The difference-in-difference and multivariate logistic regression analyses did not show strong evidence of any significant association between acute physical damage and access to quality health services. However, after the earthquake, access to quality health services deteriorated for both mothers with and without acute physical damage (-5.6% and − 6.2% for antenatal care, -6.5% and 0% for delivery care, and − 9.5% and − 13.1% for vaccination, respectively).
Conclusions
The earthquake adversely affected mothers’ access to quality essential health services regardless of their exposure to acute physical damage. Mothers in rural areas who avoided such damage might also have experienced long-term negative effects from the earthquake, which was likely exacerbated by other structural factors such as lower education and economic status.
Psychometric Properties of the Chinese version of the Female Muscularity Scale among Chinese young women
Authors: Tang Chanyuan , Barnhart Wesley R. , Zhang Bin , He Jinbo 
Published: February 2022

Abstract
Purpose: The Female Muscularity Scale (FMS) was specifically developed for assessing drive for muscularity in women. The current study aimed to translate the FMS into Chinese (FMS-C) and examine its psychometric properties among Chinese young women.Methods: Based on standard procedures, the FMS was translated into Chinese. With a sample of 517 Chinese women college students ( = 18.86 years), the current study examined the factor structure, reliability, and convergent and incremental validity of the FMS-C.Results: Results showed a 2-factor structure including attitudes and behaviors of the FMS-C. The internal consistency reliability (Cronbach’s α) was .91 for the total FMS-C scale and .89 and .88 for Attitudes and Behaviors subscales, respectively. Results also revealed evidence for good convergent and incremental validity of the FMS-C.Conclusion: Findings suggest that the FMS-C can be a useful tool to measure both attitudes and behaviors underlying drive for muscularity and muscle tone concerns among Chinese young women.Level of Evidence: Level V, cross-sectional descriptive study
Provider Perspectives on Emergency Department Initiation of Medication Assisted Treatment for Alcohol Use Disorder
Authors: Philippine Thibault , Forsgren Ethan , DeWitt Cassandra , Carter Inanna , McCollough Maureen , Taira Breena R. 
Published: February 2022

Abstract
BackgroundAlcohol use disorder (AUD) is ubiquitous and its sequelae contribute to high levels of healthcare utilization, yet AUD remains undertreated. The ED encounter represents a missed opportunity to initiate medication assisted treatment (MAT) for patients with AUD. The aim of this study is to first identify barriers and facilitators to the treatment of AUD in the ED, and second to design interventions to address identified barriers. MethodsUsing an implementation science approach based in the Behavior Change Wheel framework, we conducted qualitative interviews with staff to interrogate their perspectives on ED initiation of AUD treatment. Subjects included physicians, nurses, nurse practitioners, clinical social workers, and pharmacists. Interviews were thematically coded using both inductive and deductive approaches and constant comparative analysis. Themes were further categorized as relating to providers’ capabilities, opportunities, or motivations. Barriers were then mapped to corresponding intervention functions. ResultsFacilitators at our institution included time allotted for continuing education, the availability of clinical social workers, and favorable opinions of MAT based on previous experiences implementing buprenorphine for opioid use disorder. Capability barriers included limited familiarity with naltrexone and difficulty determining which patients are candidates for therapy. Opportunity barriers included the limited supply of naltrexone and a lack of clarity as to who should introduce naltrexone and assess readiness for change. Motivation barriers included a sense of futility in treating patients with AUD and stigmas associated with alcohol use. Evidence-based interventions included multi-modal provider education, a standardized treatment algorithm and order set, selection of clinical champions, and clarification of roles among providers on the team. ConclusionsWe used the Behavior Change Wheel framework to transform qualitative interview data into evidence-based interventions to guide the ED rollout of MAT for patients with AUD.
Semi-analytical model for TSI estimation of inland water bodies from Sentinel 2 imagery
Authors: Sherjah P. Y. , Sajikumar N. , Nowshaja P. T. 
Published: February 2022

Abstract
Regular monitoring of inland water bodies is essential to identify the areas of deteriorating water quality and to take measures to curb the impairment. The present study aims to develop a semi-analytical model for estimating Trophic State Index (TSI) from Sentinel 2 (S2) imagery. A semi-analytical algorithm, QAA-v6, is parameterized for S2 data (referred to as QAA-S2) based on the correlation between the retrieved inherent optical properties (IOPs) from S2 imagery and the measured TSI data of Milford Lake in the USA. The accuracy of estimation of TSI by this modified model from three different lakes located in USA and from one lake in India has increased by almost 50%, when compared with that of QAA-v6. A correlation analysis of the retrieved IOPs from QAA-S2 using the outputs of three atmospheric correction processors (ACPs) (namely C2RCC, Acolite and Sen2Cor) was carried out and C2RCC gave the least mean absolute percentage error (MAPE&lt;8%) for TSI estimation. TSI estimation using single-scattering albedo (u) at B5 and B6 bands of S2 was reasonable (MAPE&lt;12%) to mark them as computationally efficient estimators of TSI. These results indicate the usefulness and transferability of the QAA-S2 to the various parts of the globe for estimating TSI.
HOW TO EDUCATE STUDENT BECOME COMPETENT ENTREPRENEURS
Authors: Supardi Endang , Islamy Fahmi Jahidah , Muhidin Sambas Ali , Sutarni Nani 
Published: February 2022

The purpose of this study was to examine the direct or indirect effect between the entrepreneurship education variable and the student entrepreneurship competence variable in Vocational High School students. This study used a quantitative approach with the Survey Method (Explanatory Survey Method), and the test uses path analysis. The number of samples in this study found 100 students from 25 Public and Private Vocational High Schools accredited-A in the city of Bandung. The results showed that (1) entrepreneurship education had a significant effect on entrepreneurial intentions, both directly and indirectly, (2) entrepreneurship education had a significant direct effect on student entrepreneurial competencies, (3) and student entrepreneurial competencies had a significant influence on entrepreneurial intentions. This is because the results can illustrate that entrepreneurship education in vocational high schools is good, it can be seen from the score of the entrepreneurship education variable in the high category and the form of entrepreneurship learning in vocational high schools is good. Entrepreneurship education has the highest direct influence on students' entrepreneurial competence variables. Entrepreneurship education has a significant effect on entrepreneurial intentions, but if the competence variable becomes a mediating variable, it can further increase students' entrepreneurial intentions. The results of this study are expected to be considered by vocational high schools to provide entrepreneurship education to students, so that students' competence and interest in entrepreneurship can increase.