bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single-Shot Lumbar Erector Spinae Plane Block in Total Hip Replacement: A Randomized Clinical Trial
Authors: Chan Anyon , Ng Tony K. T. , Tang Bruce Y. H. 
Published: August 2022

BACKGROUND:
Lumbar erector spinae plane block (ESPB) has been proposed to relieve pain after total hip replacement (THR), but high-quality evidence is scarce.

METHODS:
This double-blinded (patient and assessor) randomized clinical trial, performed in 2 tertiary centers in Hong Kong, recruited patients undergoing primary unilateral THR under general anesthesia (GA) who received either single-shot ESPB at L1 (treatment arm) or no block (control arm). Patients were followed up on the first day postoperatively. We hypothesized that compared to no block, a single-shot lumbar ESPB at L1 would reduce postoperative fentanyl use and postoperative pain scores. Primary outcomes were intravenous fentanyl use at 12 and 24 hours postoperatively, along with pain intensity in numeric rating scale (0–10) at rest and upon movement on the first day postoperatively. Per-protocol analysis was performed. Mann-Whitney U test was used to compare the outcomes between both groups, and median difference was derived from the Hodges-Lehmann estimator.

RESULTS:
Seventy-one patients were randomized (n = 36 in treatment arm, n = 35 in control arm). The median amount of fentanyl consumed at 12 hours postoperatively was 210 (quartiles, 140.5–363) μg for the ESPB group and 165 (quartiles, 77.5–330.5) μg for the control group, while at 24 hours postoperatively, it was 409 (quartiles, 221–636.5) μg for the former and 349 (quartiles, 114–626.5) μg for the latter. The median differences in fentanyl consumption 12 and 24 hours postoperatively were 39 μg (95% confidence interval [CI], −40 to 116; P = .463) and 41 μg, respectively (95% CI, −83.5 to 199.5; P = .474), which were statistically insignificant. The median pain score at rest was 3 for both the ESPB group (quartiles, 0–5) and the control group (quartiles, 0–4.5), while upon movement, it was 7 for both the former (quartiles, 6–8) and the latter (quartiles, 4.5–8.5). The median difference in pain scores between both groups was 0 at rest (95% CI, −1 to 1; P = .890) and upon movement (95% CI, −1 to 1; P = .509).

CONCLUSIONS:
This trial did not demonstrate that ESPB at L1 improved analgesia following THR.
Case studies from the experience of early career researchers in East Africa in building community engagement in research
Authors: Bargul Joel L. , Mkwashapi Denna M. , Namagembe Imelda , Nakityo Immaculate , Nakimuli Annettee , Byamugisha Josaphat , Semakula Daniel , Seeley Janet , Sewankambo Nelson K. 
Published: August 2022

Background: In this paper, we explain how three early career researchers actively engaged community members in their health research projects in Kenya, Tanzania and Uganda, and what was learnt from the experience. The research project in Kenya was on camel trypanosomiasis and the role of camel biting keds (or louse flies) in disease transmission. The project in Tanzania looked at the effect of human immunodeficiency virus and antiretroviral therapy on fertility and ascertained the trends in the use of family planning services amongst women of reproductive age. The focus of the project in Uganda was the implementation of maternal death surveillance and the response policy to determine the cause of maternal deaths and how they might be prevented. Methods: In the three different settings, efforts to ensure local community engagement provided a focus for the researchers to hone their skills in explaining research concepts and working in partnership with community members to co-develop ideas, their research methods and outputs. Results: Involvement of communities in scientific research, which entailed a two-way mutual engagement process, led to (i) generation of new research ideas that shaped the work, (ii) strengthened mutual trust, and (iii) promoted uptake of research findings. Conclusion: Our key findings strongly support the need for considering community engagement as one of the key components in research studies.
Patient satisfaction with mental and physical health services: Findings from a UK-wide online survey
Authors: Kirkham Elizabeth J. , Fletcher-Watson Sue , Beange Iona , Chan Stella W.Y. , Lawrie Stephen M. 
Published: August 2022

Introduction - Despite extensive debate surrounding mental health services in the UK, there is little empirical evidence regarding the views of those who use them. We therefore used data collected as part of a wider survey to examine satisfaction amongst those seeking treatment from mental and physical health services. Methods – An online survey designed with input from people with experience of mental illness was used to measure satisfaction with NHS mental and physical health services at first contact and in the previous 12 months. Results – A total of 2187 people responded. During the 12 months prior to the survey, 526 respondents had sought mental health care and 1379 had sought physical health care. Participants were significantly more satisfied with their most recent contact with mental health services (48.1% very/satisfied) than with their first contact (38.2% very/satisfied). More than 1 in 10 respondents who sought mental health care (11.4%) stated that they received no treatment/support from the NHS, compared to approximately 1 in 20 respondents who sought physical health care (4.6%). Of those who received the mental health treatment they requested (n = 424), most were satisfied or very satisfied with their care (54.7%), although this was lower than the corresponding figure (77.9%) for satisfaction with physical health care received (n = 1190). Conclusion –There was evidence that mental health services are satisfactory for a slim majority of users, but people were generally more satisfied with NHS physical health care. This survey was conducted in the year prior to the coronavirus disease 2019 pandemic. Future research could examine what influences satisfaction with care and whether this picture has changed following the emergence of the pandemic and consequent impact on health service delivery and daily life.
Fun Shopping: A Randomized Field Experiment on Gamification
Authors: Ho Yi-Jen (Ian) , Liu Siyuan , Wang Lei 
Published: August 2022

Spotlight Gamification is an emerging digital strategy to engage users across different business domains. Gamification, defined as using game-design elements in nongaming contexts, shows great potential across domains such as education, business, and health. The significance of gamification is highlighted by a $7.17 billion global market in 2019 and is projected to reach more than $40 billion by 2024. This study examines two popular badges and leaderboards that utilize self-determination and social-comparison mechanisms to promote user engagement. We conduct a randomized field experiment (A/B testing) to quantify these effects in one of the largest shopping malls in Asia and further contrast the two games against coupons regarding various shopping outcomes. Quantitatively, badging and leaderboarding promote sales by 21.5% and 22.5% in the treatment period, respectively, whereas couponing delivers a more potent effect of 31.7%. In the posttreatment period, the gamification impacts remain significant, whereas the influence of couponing fades out. Besides, the additional analyses document the salient heterogeneous treatment effects across gender, age, and income. We also zoom in on the contrast between badges and leaderboards, showing that badging is a balanced tool for attracting the general public and leaderboarding is a double-edged sword that could encourage self-reinforcing or self-banishing. Finally, gamification encourages consumers to do more exploration, leading to significant increases in sales.
Short Communication: Evaluation of F6 generation of upland rice promising lines for drought stress tolerance
Authors: MUSTIKARINI ERIES DYAH , LESTARI TRI , SANTI RATNA , PRAYOGA GIGIH IBNU , CAHYA ZIKRI 
Published: August 2022

Abstract. Mustikarini ED, Lestari T, Santi R, Prayoga GI, Cahya Z. 2022. Short Communication: Evaluation of F6 generation of upland rice promising lines for drought stress tolerance. Biodiversitas 23: 3401-3406. Water is important in metabolic processes affecting rice crop growth and development. Drought stress can decrease rice production, necessitating the development ofdrought-tolerant varieties. Selection of drought-tolerant can be done during the critical period plant booting phase. Thisresearch aimed to determine promising linesof upland rice tolerant to drought stress. This research was conducted from December 2019 toMay 2020 at the experimental farmofthe Faculty of Agriculture, Fisheries and Biology, Universitas Bangka Belitung. The research was laid out in a completely randomized design with a single-factortreatment. The treatment was rice genotypes consisting of 10 lines and 2 checkvarieties; each was 3 replicates. The results showed that the droughtstressin the plant booting phase of rice plants significantly affected the plant heigh character of the plant, grains number per panicle, the weight of grain per panicle, the age of flowering, and harvest time, but gave no significant effect on the number of leaves, the number of productive tillers, roots length. The upland rice lines 23A-56-30-25-1, 23A-56-30-25-12, and 23A-56-30-25-13 showed good drought stress tolerance based on leaf rolling, leaf drying, crop yield, and plant growth percentage.
Morphological variations and molecular phylogeny of Oryzias sarasinorum Popta, 1905 (Ricefish) from Lake Lindu, Central Sulawesi, Indonesia
Authors: ZAINAL SYECH , TELLU ANDI TANRA , KASIM AMIRUDDIN 
Published: August 2022

Abstract. Zainal S, Tellu AT, Kasim A. 2022. Morphological variations and molecular phylogeny of Oryzias sarasinorum Popta, 1905 (Ricefish) from Lake Lindu, Central Sulawesi, Indonesia. Biodiversitas 23: 3443-3451. Oryzias sarasinorum Popta, 1905 is a well-studied species endemic to Lake Lindu, Central Sulawesi, Indonesia and identified as scarce. This study aims to describe the morphological variation and phylogeny of Oryzias sarasinorum Popta, 1905 from Lake Lindu, Central Sulawesi Province, Indonesia. This research was conducted in February 2022. 10 samples were collected and preserved on 95% ethanol for morphological analysis and molecular purposes. Our morphological analysis showed that the meristic counts, morphometric measurement, and phylogenetic analysis also resolved that the samples that were analyzed are indeed an endemic species of O. sarasinorum from Lake Lindu. Finally, we expect there are future studies that pay attention to well-resolved phylogenies and thereby remove additional noise from the analysis. The research data are expected to contribute to the preservation and utilization of one of Indonesia's important biodiversity resources.
The insights of smallholder farmers on special attributes of the genetically robust mule
Authors: DESTA TAKELE TAYE , TEKLEMARIAM HAIMANOT , MULUGETA TEWODROS 
Published: August 2022

Abstract. Desta TT, Teklemariam H, Mulugeta T. 2022. The insight of smallholder farmers on special attributes of the genetically robust mule. Biodiversitas 23: 3561-3566. A mule (Equus asinus X Equus caballus) is the offspring of a jack, a mature male donkey, and a mare, a mature female horse. Mule is the artifact of distant hybridization, and interspecific breeding has endowed mule with appreciable hardiness. In the history of humans, mule breeding represents a novel undying, and successful traditional biotechnology. This qualitative study reports the advantages and disadvantages of using mules as working and riding equid and insights of smallholder farmers on mule’s behavior and robustness. For most of the socio-economically important traits reported mule surpasses both the parental species, donkey and horse. This superiority is most likely associated with the genetic robustness of mules aroused from interspecific hybridization. It was reported that a mare mule is more intelligent, and quite the opposite, it is more aggressive than its male counterpart. Presumably, X-inactivation in distant hybrid animals like mules possessing heterologous X-chromosomes is suppressed; consequently, some of the X-chromosome genes might be escaped the inactivation process which makes the mare mule produce more of the protein products and surpass its male counterpart. The general sterility of mare mule may have also made it to invest virtually none in the costly task, nurturing of offspring. Mule's sterility and aggression make some of the community members develop negative insights. Regardless of this, the mule is highly appreciated for the various services it deliverstothe rural community.
Proline-related gene expressions contribute to physiological changes of East Nusa Tenggara (Indonesia) local rice cultivars during drought stress
Authors: SALSINHA YUSTINA CAROLINA FEBRIANTI , NURBAITI SITI , SEBASTIAN ALFINO , INDRADEWA DIDIK , PURWESTRI YEKTI ASIH , RACHMAWATI DIAH 
Published: August 2022

Abstract. Salsinha YCF, Nurbaiti S, Sebastian A, Indradewa D, Purwestri YA, Rachmawari D. 2022. Proline-related gene expressions contribute to physiological changes of East Nusa Tenggara (Indonesia) local rice cultivars during drought stress. Biodiversitas 23: 3573-3583. An osmoregulation response is one of the mechanisms of adaptation to drought stress. Concerning the synthesis and catabolism of proline as an osmoprotectant, this research aims to study the involvement of proline in regulating physiological change in local rice cultivars from Nusa Tenggara Timur (NTT), Indonesia. Five rice cultivars consisting of Ciherang (drought susceptible) and Situ Bagendit (drought tolerant) and three local rice cultivars, namely Gogo Jak (GJ), Kisol Manggarai (KM), and Boawae Seratus Malam (BSM) were used. Drought treatments were carried out using the fraction of transpirable soil water (FTSW) with control (FTSW 1) and severe drought (FTSW 0.2). The upregulation of OsP5CS and OsP5CR as proline synthesis genes in GJ leaves led to higher proline levels. At the KM cultivar, there was an upregulation of OsPRODH related to proline catabolism. Furthermore, OsNHX1, responsible for proline transport, was higher in the GJ cultivar. The presence of proline also correlated with physiological adaptations. Proline accumulation due to the activation of proline-related gene expressions caused less physiological changes and antioxidant activity reduction and has led to maximum water absorption during a severe drought in the BSM cultivar. The analysis showed non-significant decreased levels of chlorophyll-a and increased levels of chlorophyll-b, carotenoids, and anthocyanins of drought-tolerant cultivars lead to higher leaf number, plant height, and tiller number under drought. Meanwhile, varied activity levels of superoxide dismutase (SOD), ascorbate peroxidase (APX), and catalase (CAT) were observed in line with the slight increase in H2O2 and malonaldehyde (MDA) levels during severe drought.
Aquatic biodiversity in a pond on the airport landside areas through environmental DNA metabarcoding: Implementation for Aviation Security Management
Authors: PRIYONO DWI SENDI , REZA AKBAR , EPRILURAHMAN RURY , YUDHA DONAN SATRIA , MUFTI FARADINA , FAUZY NOORMAN HENDRY , Triyono Raden Bambang , ADHI PANGGIH KURNIA 
Published: August 2022

Abstract. Priyono DS, Reza A, Eprilurahman R, Yudha DS, Mufti D, Fauzy NH, Triyono RB, Adhi PK. 2022. Aquatic biodiversity in a pond on the airport landside areas through environmental DNA metabarcoding: Implementation for Aviation Security Management. Biodiversitas 23: 3639-3646. Environmental DNA (eDNA) has become a widely used tool for aquatic biodiversity monitoring, as well as for formulating effective landscape management strategies. Yogyakarta International Airport (YIA), Indonesia, has a green belt landscape located on the Indian Ocean coast. YIA's landscape biodiversity analysis is still unexplored. Herein, we first used high throughput sequencing DNA metabarcoding to identify and investigate aquatic biodiversity in a pond on the airport landside areas. The metabarcoding eDNA sequencing analysis yielded 224,737 raw reads from the metagenomics utilizing Illumina MiSeq sequencing. We identified 588 eukaryote species from 205 families and 300 genera. Actinopteri is the most dominant class with a diversity of 160 taxa, followed by Mammalia (88), Amphibia (60), and Chlorophyceae (25). At the order level, Anura has the highest order diversity (50), followed by Rodentia (31), Chiroptera (17), Eulipotyphla (16), Squamata (15), and Cypriniformes (14). We found that Plasmodium was the genus with the highest relative abundance in this pond (18,030 reads). Furthermore, the large variety of fish and other taxa in this pond may attract waterbirds, increasing the risk of bird strike. The abundance of Plasmodium sp. in this airport area is an important issue, especially regarding airport malaria risk. Integration of biodiversity monitoring using eDNA with aviation security management provides valuable information for the airport's wildlife hazard management plan. To prevent the recurrence of bird strikes and prevent airport malaria, aviation security strategies utilizing habitat management approaches are recommended.
Cancer tracking system improves timeliness of liver cancer care at a Veterans Hospital: A comparison of cohorts before and after implementation of an automated care coordination tool
Authors: Zhang Yapei , Mezzacappa Catherine , Shen Lin , Ivatorov Amanda , Petukhova-Greenstein Alexandra , Mehta Rajni , Ciarleglio Maria , Deng Yanhong , Levin Woody , Steinhardt Steve , Connery Donna , Pineau Michael , Onyiuke Ifeyinwa , Taylor Caroline , Rose Michal G. , Taddei Tamar H. 
Published: August 2022

Introduction
Hepatocellular carcinoma (HCC) requires complex care coordination. Patient safety may be compromised with untimely follow-up of abnormal liver imaging. This study evaluated whether an electronic case-finding and tracking system improved timeliness of HCC care.

Methods
An electronic medical record-linked abnormal imaging identification and tracking system was implemented at a Veterans Affairs Hospital. This system reviews all liver radiology reports, generates a queue of abnormal cases for review, and maintains a queue of cancer care events with due dates and automated reminders. This is a pre-/post-intervention cohort study to evaluate whether implementation of this tracking system reduced time between HCC diagnosis and treatment and time between first liver image suspicious for HCC, specialty care, diagnosis, and treatment at a Veterans Hospital. Patients diagnosed with HCC in the 37 months before tracking system implementation were compared to patients diagnosed with HCC in the 71 months after its implementation. Linear regression was used to calculate mean change in relevant intervals of care adjusted for age, race, ethnicity, BCLC stage, and indication for first suspicious image.

Results
There were 60 patients pre-intervention and 127 post-intervention. In the post-intervention group, adjusted mean time from diagnosis to treatment was 36 days shorter (p = 0.007), time from imaging to diagnosis 51 days shorter (p = 0.21), and time from imaging to treatment 87 days shorter (p = 0.05). Patients whose imaging was performed for HCC screening had the greatest improvement in time from diagnosis to treatment (63 days, p = 0.02) and from first suspicious image to treatment (179 days, p = 0.03). The post-intervention group also had a greater proportion of HCC diagnosed at earlier BCLC stages (p<0.03).

Conclusions
The tracking system improved timeliness of HCC diagnosis and treatment and may be useful for improving HCC care delivery, including in health systems already implementing HCC screening.
Seroepidemiological study of Japanese encephalitis virus in Chiang Mai: Immunity and susceptibility 28 years after introduction of a vaccination programme
Authors: Sudjaritruk Tavitiya , Kaewpoowat Quanhathai , Prasarakee Chanidapa , Sarachai Saowalak , Taurel Anne-Frieda , Sricharoen Natthanidnan , Assawawongprom Phatraporn , Saheng Jutamad , Harris Rebecca , Nealon Joshua , Yoksan Sutee 
Published: August 2022

BackgroundThailand has introduced a nationwide vaccination against Japanese encephalitis virus (JEV) into National Immunization Programme since the 1990’s. To improve the understanding of immunity and susceptibility of the population after 28 years of a vaccination programme, we conducted a JEV seroepidemiological study in a JEV-endemic area of Thailand.MethodsAn age-stratified, population-based, seroepidemiological study was conducted in Chiang Mai, Thailand–a northern Thai province where is an endemic area of Japanese encephalitis. Nine districts were chosen based on administrative definition: rural (n= 3); urban (n= 3); and peri-urban (n= 3). Within each district, eligible participants were randomly selected from 3 age groups: adolescents (10–20 years); adults (21–50 years); and older adults/elderly (≥51 years) by computer randomization. Plaque reduction neutralization tests (PRNT50and PRNT90) were performed to measure neutralizing antibodies to JEV. To account for the cross-reactivity of JEV and other flaviviruses, JEV seroprotection was defined according to age, previous history of JEV vaccination, and PRNT50/PRNT90levels of study participants.ResultsOverall, 279 adolescents, 297 adults, and 297 older adults/elderly were enrolled from nine districts. Age-stratified, protocol-defined, cluster-adjusted JEV seroprotection rates were 61% (95% CI: 48–73%), 43% (95% CI: 31–57%), and 52% (95% CI: 37–67%) for adolescents, adults, and older adults/elderly, respectively. Living in peri-urban districts, having a history of prior dengue virus infection, and previously receiving mouse brain-derived JEV vaccine were significantly associated with seroprotection to JEV in adolescents. Older age and male sex were associated with seroprotection for adults; and only male sex was the associated factor for older adults/elderly (P<0.05).ConclusionsApproximately half of population living in a JEV-endemic area demonstrated seroprotection to JEV. Ongoing nationwide surveillance on JEV seropepidemiology is an important strategy to understand the evolving population-level immunity to JEV, and to help formulating the appropriate recommendations on JE immunization.
Cultural and linguistic adaption and testing of the Health Literacy Questionnaire (HLQ) among healthy people in Korea
Authors: Park Jin-Hee , Osborne Richard H. , Kim Hee-Jun , Bae Sun Hyoung 
Published: August 2022

Backgrounds
This study administered the Health Literacy Questionnaire (HLQ) among Korean adults to examine its factor structure, reliability, and validity.

Methods
The HLQ items were translated and culturally adapted to the Korean context. The convenience sampling method was used, and data were collected. The difficulty level, confirmatory factor analysis (CFA) using diagonal weighted least squares (DWLS) estimator in R, discriminant validity, and composite reliability were performed.

Results
The easiest scale to obtain a high score was “Scale 4. Social support for health” and the hardest was “Scale 7. Navigating the healthcare system.” Nine one-factor models fitted well. The nine-factor structural equation model fitted the data well. All HLQ scales were homogenous, with composite reliability.

Conclusions
The Korean version of the HLQ has a strong construct and high composite reliability when applied to Korean adults.