bluuebunny/crossref_metadata_2025_split huggingface dataset:
Confirmed reinfection with SARS‐CoV‐2 during a pregnancy: A case report
Authors: Sengpiel Verena , Carlsson Ylva , Liljeqvist Jan‐Åke , Elfvin Anders , Fyhr Ing‐Marie , Lundgren Anna , Nyström Kristina , Bemark Mats , Gisslen Magnus , Ringlander Johan 
Published: February 2022

AbstractPregnancy might impact immunity after SARS‐CoV‐2 infection and/or vaccination. We describe the first case of reinfection with SARS‐CoV‐2 during a pregnancy. While the mother lacked detectable antibodies 2 months after the first infection, both mother and baby had IgG antibodies at delivery. Infection did not cause any adverse pregnancy outcome.
Schwannoma of the lateral nasal wall: A case report
Authors: Barati Behrouz , Mohseni Malihe , Asadi Mahboobe , Mangeli Forogh 
Published: February 2022

AbstractNasal schwannomas account for about 4% of head and neck schwannomas. We report a rare case of lateral nasal wall schwannoma presenting as a nasal mass in a 70‐year‐old man.
Oxidation of 5‐Hydroxymethyl Furfural to 2,5‐Furan Dicarboxylic Acid Under Mild Aqueous Conditions Catalysed by MIL‐100(Fe) Metal‐Organic Framework
Authors: Chamberlain Thomas W. , Degirmenci Volkan , Walton Richard I. 
Published: February 2022

AbstractWe present the use of the redox active MIL‐100(Fe) metal‐organic framework (MOF) as a catalyst for the oxidation of 5‐hydroxymethyl furfural (HMF) into 2,5‐furan dicarboxylic acid (FDCA) in water. The MOF is synthesised in water alone under mild hydrothermal conditions and 1H NMR is used to analyse the products of HMF oxidation. The MOF in combination with the co‐catalyst TEMPO provides a total selectivity of desired products of 74 % with a maximum FDCA yield of 57 % seen after 24 hours at only 70 °C. The catalyst is recycled ten times with no loss in activity and no evidence of a reduction in the crystallinity of the MOF.
Ultrasound‐Assisted Slug‐Flow Tubular Crystallization for Preparation of Fine Ibuprofen Crystals
Authors: Yuan Mingpu , Wang Jingkang , Huang Xin , Wang Ting , Wang Na , Zhou Lina , Hao Hongxun 
Published: February 2022

AbstractIbuprofen fine crystals prepared by commonly used methods have some problems such as low‐crystallinity product and uneven distributed particle size. An ultrasonic‐assisted tubular crystallization system was developed. The effects of tubular crystallization temperature, supersaturation, residence time, surfactant, and flow pattern on the crystal size distribution and average particle size were studied. It was found that ultrasound promotes nucleation and reduces crystal aggregation. Ibuprofen crystals with an average particle size of 6.23 μm were formed owing to the high degree of continuous supersaturation and promoted micromixing. Finally, a possible mechanism of enhancement of micromixing under ultrasonic and slug flow on tubular crystallization was proposed.
A New Class of Task‐Specific Imidazolium Salts and Ionic Liquids and Their Corresponding Transition‐Metal Complexes for Immobilization on Electrochemically Active Surfaces
Authors: Seidl Vera , Romero Angel H. , Heinemann Frank W. , Scheurer Andreas , Vogel Carola S. , Unruh Tobias , Wasserscheid Peter , Meyer Karsten 
Published: February 2022

AbstractAdding to the versatile class of ionic liquids, we report the detailed structure and property analysis of a new class of asymmetrically substituted imidazolium salts, offering interesting thermal characteristics, such as liquid crystalline behavior, polymorphism or glass transitions. A scalable general synthetic procedure for N‐polyaryl‐N’‐alkyl‐functionalized imidazolium salts with para‐substituted linker (L) moieties at the aryl chain, namely [LPhmImHR]+ (L=Br, CN, SMe, CO2Et, OH; m=2, 3; R=C12, PEGn; n=2, 3, 4), was developed. These imidazolium salts were studied by single‐crystal X‐ray diffraction (SC‐XRD), NMR spectroscopy and thermochemical methods (DSC, TGA). Furthermore, these imidazolium salts were used as N‐heterocyclic carbene (NHC) ligand precursors for mononuclear, first‐row transition metal complexes (MnII, FeII, CoII, NiII, ZnII, CuI, AgI, AuI) and for the dinuclear Ti‐supported Fe‐NHC complex [(OPy)2Ti(OPh2ImC12)2(FeI2)] (OPy=pyridin‐2‐ylmethanolate). The complexes were studied concerning their structural and magnetic behavior via multi‐nuclear NMR spectroscopy, SC‐XRD analyses, variable temperature and field‐dependent (VT‐VF) SQUID magnetization methods, X‐band EPR spectroscopy and, where appropriate, zero‐field 57Fe Mössbauer spectroscopy.
Impact of chronic kidney disease on clinical outcomes in patients with Stage B progressive aortic regurgitation (mild to moderate and moderate grades)
Authors: Hwang Ji‐won , Kim Dong‐Gil , Kim Hakju , Kwak Jae‐Jin , Cho Sung Woo , Bae Da Mi , Shin Yoon Cheol , Doh Joon Hyung , Kwon Sung Uk , Namgung June , Lee Sung Yun 
Published: February 2022

AbstractBackgroundChronic kidney disease (CKD) is a significant comorbidity in patients with heart failure and valvular heart disease. Renal impairment is not well evaluated in the patients with Stage B progressive aortic regurgitation (AR) (mild to moderate and moderate grades in this study), for estimating outcome.HypothesisWe sought to investigate the prognostic factor, especially CKD, in the patients with progressive AR.MethodsWe enrolled 262 patients with Stage B progressive AR and preserved left ventricular systolic function (ejection fraction ≥ 50%). Based on the presence of CKD, the patients were divided into CKD (n = 70) and non‐CKD (n = 192) groups, which CKD was defined as estimated glomerular filtration rate < 60 ml/min/1.73 m2. The primary outcome was major adverse cardiac events (MACEs), including cardiac death, myocardial infarction, hospitalization for heart failure, and aortic valve replacement.ResultsThe median follow‐up duration was 41.5 (interquartile range: 16.2–71.7) months. Between groups, the CKD patients were older; they had a higher pulse pressure and higher incidence of hypertension, diabetes mellitus, dyslipidemia, cerebrovascular accident, and atrial fibrillation. Compared to the non‐CKD group, the CKD group had lower eʹ velocity (4.36 ± 2.21 vs. 5.20 ± 2.30 cm/s, p = .009), higher right ventricular systolic pressure (38.02 ± 15.79 vs. 33.86 ± 11.77 mmHg, p = .047). The CKD group was associated with increased risk of MACEs (41.4% vs. 22.4%; unadjusted hazard ratio [HR]: 1.78, 95% confidence interval [CI]: 1.11–2.85, p = .017). In multivariate Cox regression analyses, the risk of MACEs was significantly different between groups (adjusted HR: 1.71, 95% CI: 1.11–2.62, p = .015); furthermore, the risk of hospitalization for heart failure (10.0% vs. 2.6%; adjusted HR: 2.30, 95% CI: 1.16–4.55, p = .017) was significantly higher in the CKD group than in the non‐CKD group.ConclusionsIn patients with Stage B progressive AR, CKD is an independent prognostic factor for clinical outcomes (composite clinical outcome, hospitalization for heart failure).
Utilization and in‐hospital complications of catheter ablation for atrial fibrillation in patients with obesity and morbid obesity
Authors: Prasitlumkum Narut , Chokesuwattanaskul Ronpichai , Kaewput Wisit , Thongprayoon Charat , Bathini Tarun , Boonpheng Boonphiphop , Vallabhajosyula Saraschandra , Cheungpasitporn Wisit , Jongnarangsin Krit 
Published: February 2022

AbstractBackgroundReal‐world data on atrial fibrillation (AF) ablation outcomes in obese populations have remained scarce, especially the relationship between obesity and in‐hospital AF ablation outcome.HypothesisObesity is associated with higher complication rates and higher admission trend for AF ablation.MethodsWe drew data from the US National Inpatient Sample to identify patients who underwent AF ablation between 2005 and 2018. Sociodemographic and patients' characteristics data were collected, and the trend, incidence of catheter ablation complications and mortality were analyzed, and further stratified by obesity classification.ResultsA total of 153 429 patients who were hospitalized for AF ablation were estimated. Among these, 11 876 obese patients (95% confidence interval [CI]: 11 422–12 330) and 10 635 morbid obese patients (95% CI: 10 200–11 069) were observed. There was a substantial uptrend admission, up to fivefold, for AF ablation in all obese patients from 2005 to 2018 (p < .001). Morbidly obese patients were statistically younger, while coexisting comorbidities were substantially higher than both obese and nonobese patients (p < .01) Both obesity and morbid obesity were significantly associated with an increased risk of total bleeding, and vascular complications (p < .05). Only morbid obesity was significantly associated with an increased risk of ablation‐related complications, total infection, and pulmonary complications (p < .01). No difference in‐hospital mortality was observed among obese, morbidly obese, and nonobese patients.ConclusionOur study observed an uptrend in the admission of obese patients undergoing AF ablation from 2005 through 2018. Obesity was associated with higher ablation‐related complications, particularly those who were morbidly obese.
Tar Spot: a New Fungus Amongus
Authors: Winsor Susan 
Published: February 2022

AbstractTar spot fungus is a new reason to stay on your corn‐scouting toes, especially if you’re in the central Corn Belt. It was first found in northern Illinois and Indiana in 2015 before spreading to 12 other states and one Canadian province. Corn yield losses range from 20 to 60 bu/ac, and tar spot can also trigger complications such as lodging. The article will tell you what to look for as well as provide prevention and management tips. Information herein comes from members of The Crop Protection Network, a collaboration of 35 U.S. and Canadian plant pathologists. Special thanks to Michigan State University, Ontario Ministry of Agriculture, Purdue University, and the Universities of Kentucky, Iowa, Minnesota, and Wisconsin–Madison. Earn 1 CEU in Integrated Pest Management by reading the article and taking the quiz at https://bit.ly/3H4KX1x. View all CEUs online at https://web.sciencesocieties.org/Learning‐Center/Courses.
Enabling Efficient Aerobic 5‐Hydroxymethylfurfural Oxidation to 2,5‐Furandicarboxylic Acid in Water by Interfacial Engineering Reinforced Cu−Mn Oxides Hollow Nanofiber
Authors: Dong Xuexue , Wang Xuyu , Song Hua , Zhang Yue , Yuan Aihua , Guo Zengjing , Wang Qian , Yang Fu 
Published: February 2022

AbstractHerein, a one‐dimensional hollow nanofiber catalyst composed of tightly packed multiphase metal oxides of Mn2O3 and Cu1.4Mn1.6O4 was constructed by electrospinning and tailored thermal treatment procedure. The characterization results comprehensively confirmed the special morphology and composition of various comparative catalysts. This strategy endowed the catalyst with abundant interfacial characteristics of components Mn2O3 and Cu1.4Mn1.6O4 nanocrystal. Impressively, the tuning thermal treatment resulted in tailored CuI sites and surface oxygen species of the catalyst, thus affording optimized oxygen vacancies for reinforced oxygen adsorption, while the concomitant enhanced lattice oxygen activity in the constructed composite catalyst ensured the higher catalytic oxidation ability. More importantly, the regulated proportion of oxygen vacancy and lattice oxygen in the composite catalyst was obtained in the best catalyst, beneficial to accelerate the reaction cycle. Compared to other counterparts obtained by different temperatures, the CMO‐500 sample exhibited superior selective aerobic 5‐hydroxymethylfurfural (HMF) oxidation to 2,5‐furandicarboxylic acid (FDCA, 96 % yield) in alkali‐bearing aqueous solution using O2 at 120 °C, which resulted from the above‐mentioned composition optimization and interfacial engineering reinforced surface oxygen consumption and regeneration cycle. The reaction mechanism was further proposed to uncover the lattice oxygen and oxygen vacancy participating HMF conversion process.
Delicate Tuning of the Ni/Co Ratio in Bimetal Layered Double Hydroxides for Efficient N2 Electroreduction
Authors: Zou Zhi , Wu Lei , Yang Fangqi , Cao Chenliang , Meng Qiangguo , Luo Junhui , Zhou Weizhen , Tong Zhikun , Chen Jingwen , Chen Shixia , Zhou Shaodong , Wang Jun , Deng Shuguang 
Published: February 2022

AbstractElectroreduction of N2 to NH3 at ambient conditions using renewable electricity is promising, but developing efficient electrocatalysts is still challenging due to the inertness of N≡N bonds. Layer double hydroxides (LDHs) composed of first‐row transition metals with empty d‐orbitals are theoretically promising for N2 electroreduction (NRR) but rarely reported. Herein, hollow NiCo‐LDH nanocages with different Ni/Co ratios were prepared, and their electronic structures and atomic arrangements were critical. The synergetic mechanisms of Ni and Co ions were revealed, and the optimized catalytic sites were proposed. Besides, in‐situ Raman spectroscopy and 15N2 isotopic labeling studies were applied to detect reaction intermediates and confirm the origin of NH3. As a result, high NH3 yield of 52.8 μg h−1 mgcat−1 and faradaic efficiency of 11.5 % were obtained at −0.7 V, which are top‐ranking among Co/Ni‐based NRR electrocatalysts. This work elucidates the structure–activity relationship between LDHs and NRR and is instructive for rational design of LDH‐based electrocatalysts.
Clinically relevant preclinical animal models for testing novel cranio‐maxillofacial bone 3D‐printed biomaterials
Authors: Hatt Luan P. , Thompson Keith , Helms Jill A. , Stoddart Martin J. , Armiento Angela R. 
Published: February 2022

AbstractBone tissue engineering is a rapidly developing field with potential for the regeneration of craniomaxillofacial (CMF) bones, with 3D printing being a suitable fabrication tool for patient‐specific implants. The CMF region includes a variety of different bones with distinct functions. The clinical implementation of tissue engineering concepts is currently poor, likely due to multiple reasons including the complexity of the CMF anatomy and biology, and the limited relevance of the currently used preclinical models. The ‘recapitulation of a human disease’ is a core requisite of preclinical animal models, but this aspect is often neglected, with a vast majority of studies failing to identify the specific clinical indication they are targeting and/or the rationale for choosing one animal model over another. Currently, there are no suitable guidelines that propose the most appropriate animal model to address a specific CMF pathology and no standards are established to test the efficacy of biomaterials or tissue engineered constructs in the CMF field. This review reports the current clinical scenario of CMF reconstruction, then discusses the numerous limitations of currently used preclinical animal models employed for validating 3D‐printed tissue engineered constructs and the need to reduce animal work that does not address a specific clinical question. We will highlight critical research aspects to consider, to pave a clinically driven path for the development of new tissue engineered materials for CMF reconstruction.
Extramedullary early T‐cell lymphoblastic crisis in a young pregnant chronic myeloid leukemia patient: Diagnosis with fine‐needle aspiration cytology and flow cytometry
Authors: Murugan Roobashri , Gochhait Debasis , Manivannan Prabhu , Basu Debdatta 
Published: February 2022

AbstractChronic myeloid leukemia (CML) most commonly presents in chronic phase. Blast crisis in CML is usually of myeloid phenotype, whereas among lymphoid lineage, B‐cell lymphoblastic crisis is common. T lymphoblastic crisis is rare with near early T‐cell precursor (ETP) immunophenotype being exceedingly rare and very little is known about its characteristics, treatment, and prognosis. Blast crisis can occur in extramedullary sites with lymph node being the most common site. CML is also less investigated and studied in pregnancy as it is considered a disease of older adults. We report a rare case of CML presenting in extramedullary site (lymph node) as extramedullary T‐cell lymphoblastic crisis of near ETP immunophenotype in a young pregnant female, which was diagnosed on fine‐needle aspiration cytology in combination with flow cytometry.
Phylogenetic signal of sub‐arctic beetle communities
Authors: Majoros Samantha E. , Adamowicz Sarah J. 
Published: February 2022

AbstractPostglacial dispersal and colonization processes have shaped community patterns in sub‐Arctic regions such as Churchill, Manitoba, and Canada. This study investigates evolutionary community structure within the beetle (Coleoptera) families of Churchill and tests whether biological traits have played a role in governing colonization patterns from refugial and southerly geographic regions. This study quantifies sub‐Arctic beetle phylogenetic community structure for each family using the net relatedness index (NRI) and nearest taxon index (NTI), calculated using publicly available data from the Barcode of Life Data Systems (BOLD); compares patterns across families with different traits (habitat, diet) using standard statistical analysis (ANOVA) as well as phylogenetic generalized least squares (PGLS) using a family‐level beetle phylogeny obtained from the literature; and compares community structure in Churchill with a region in southern Canada (Guelph, Ontario). These analyses were also repeated at a genus level. The dominant pattern detected in our study was that aquatic families were much better represented in Churchill compared to terrestrial families, when compared against richness sampled from across Canada and Alaska. Individually, most families showed significant phylogenetic clustering in Churchill, likely due to the strong environmental filtering present in Arctic environments. There was no significant difference in phylogenetic structure between Churchill and Guelph but with a trend toward stronger clustering in the North. Fungivores were significantly more overdispersed than other feeding modes, predators were significantly more clustered, and aquatic families showed significantly stronger clustering compared to terrestrial. This study contributes to our understanding of the traits and processes structuring insect biodiversity and macroecological trends in the sub‐Arctic.
Candidate‐species delimitation in Desmognathus salamanders reveals gene flow across lineage boundaries, confounding phylogenetic estimation and clarifying hybrid zones
Authors: Pyron Robert Alexander , O’Connell Kyle A. , Lemmon Emily Moriarty , Lemmon Alan R. , Beamer David A. 
Published: February 2022

AbstractDusky Salamanders (genus Desmognathus) currently comprise only 22 described, extant species. However, recent mitochondrial and nuclear estimates indicate the presence of up to 49 candidate species based on ecogeographic sampling. Previous studies also suggest a complex history of hybridization between these lineages. Studies in other groups suggest that disregarding admixture may affect both phylogenetic inference and clustering‐based species delimitation. With a dataset comprising 233 Anchored Hybrid Enrichment (AHE) loci sequenced for 896 Desmognathus specimens from all 49 candidate species, we test three hypotheses regarding (i) species‐level diversity, (ii) hybridization and admixture, and (iii) misleading phylogenetic inference. Using phylogenetic and population‐clustering analyses considering gene flow, we find support for at least 47 candidate species in the phylogenomic dataset, some of which are newly characterized here while others represent combinations of previously named lineages that are collapsed in the current dataset. Within these, we observe significant phylogeographic structure, with up to 64 total geographic genetic lineages, many of which hybridize either narrowly at contact zones or extensively across ecological gradients. We find strong support for both recent admixture between terminal lineages and ancient hybridization across internal branches. This signal appears to distort concatenated phylogenetic inference, wherein more heavily admixed terminal specimens occupy apparently artifactual early‐diverging topological positions, occasionally to the extent of forming false clades of intermediate hybrids. Additional geographic and genetic sampling and more robust computational approaches will be needed to clarify taxonomy, and to reconstruct a network topology to display evolutionary relationships in a manner that is consistent with their complex history of reticulation.
Stability improvement of power system by cooperative virtual inertia control and reactive power control of PMSG wind generator and battery
Authors: Sato Takamasa , Alsharif Faramarz , Umemura Atsushi , Takahashi Rion , Tamura Junji 
Published: February 2022

AbstractRenewable energy generation systems are promising energy sources; however, they have a problem that they do not have, in general, inertia and synchronous power. A system with low inertial and synchronization forces has low stabilizing capability, and such systems are vulnerable to network fault and can cause large frequency fluctuations. This paper focuses on a large storage battery and a permanent magnet synchronous generator (PMSG) based variable‐speed wind power generator, and a new cooperative virtual inertia and reactive power control system between them which is based on Fuzzy Logic controller (FLC) and asymmetric hysteresis deadband is proposed and designed. Its effectiveness on the system stability enhancement during a grid fault is confirmed by simulation analyses on PSCAD/EMTDC.
Iron deficiency in heart failure patients: the French CARENFER prospective study
Authors: Cohen‐Solal Alain , Philip Jean‐Luc , Picard François , Delarche Nicolas , Taldir Guillaume , Gzara Heger , Korichi Anissa , Trochu Jean‐Noel , Cacoub Patrice ,   CARENFER Study Group
Published: February 2022

AbstractAimsIron deficiency (ID) is reported as one of the main co‐morbidities in patients with chronic heart failure (CHF), which then influences quality of life and prognosis. The CARENFER study aimed to assess the prevalence of ID in a large panel of heart failure (HF) patients at different stages of the disease.Methods and resultsThis prospective cross‐sectional nationwide study was conducted in 48 medical units in France in 2019. Serum ferritin concentration and transferrin saturation (TSAT) index were determined in all eligible patients with a diagnosis of HF. ID diagnosis was based on the European Society of Cardiology (ESC) 2016 guidelines. Patients were classified as having either a decompensated HF or a CHF. Left ventricular ejection fraction (LVEF) was categorized as preserved (≥50%), mildly reduced (40–49%), or reduced (<40%). ID diagnosis was determined in 1661 patients, of whom 1475 could be classified as having a decompensated HF or a CHF. Patients' median age was 78 years. Decompensated HF represented 60.1% of cases. The overall prevalence of ID was 49.6% (47.1–52.1). In CHF and decompensated HF patients, respectively, ID prevalence was 39.0% (35.1–43.1) and 58.1% (54.7–61.4), P < 0.001; TSAT < 20% was respectively reported in 34.7% and 70.0% of patients (P < 0.001). Patients with preserved LVEF were more likely to have an ID (57.5%) compared with patients with mildly reduced (47.4%) or reduced LVEF (44.3%) (P < 0.001).ConclusionsIron deficiency was highly prevalent in patients with decompensated HF or CHF with preserved LVEF. ID prevalence defined by TSAT was higher than by the ESC criteria in decompensated HF patients, questioning the importance of ID definition to assess its prevalence.