bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancements and Challenges in Microgrid Technology: A Comprehensive Review of Control Strategies, Emerging Technologies, and Future Directions
Authors: Dev Ark , Kumar Vineet , Khare Gaurav , Giri Jayant , Amir Mohammad , Ahmad Furkan , Jain Prince , Anand Sumant 
Published: February 2025

ABSTRACTThe concept of microgrids (MGs) as compact power systems, incorporating distributed energy resources, generating units, storage systems, and loads, is widely acknowledged in the research community. Globally, nations are adopting MGs to access clean, affordable, and reliable energy solutions. However, effective MG operation encounters several challenges: stability issues, power quality concerns, inadequate energy management, cybersecurity threats, regulatory complexities, economic barriers, market dynamics, and limited public acceptance. This paper presents a systematic literature review encompassing recent advancements in MG technology. It delves into MG architecture, diverse control objectives, associated methodologies, emerging control approaches, future challenges, and potential solutions. This review focuses on existing control methods, particularly those addressing frequency and voltage stability, energy management, threat mitigation and explores a spectrum of engineering and nonengineering challenges within MG systems, proposing viable solutions. This review paper also explores recent control strategies for frequency regulation in MG system, utilizing MATLAB simulations to demonstrate their effectiveness. Additionally, the paper examines the application of cutting‐edge technologies like machine learning, blockchain, reinforcement learning, neural networks, edge computing, and the internet of things (IoT) to mitigate concerns in expanding MG systems. The paper concludes by summarizing key findings, outlining avenues for future research, and offering a comprehensive perspective on the current state and future directions of MG research.
Integration of Solar PV Panels in Electric Vehicle Charging Infrastructure: Benefits, Challenges, and Environmental Implications
Authors: Tripathi Abhishek Kumar , Sree Lakshmi G. , Mishra Heena , Chapala Shravani , Alwetaishi Mamdooh , Atamurotov Farruh , Benti Natei Ermias , Sura Sreekanth , Ahamed Saleel C. 
Published: February 2025

ABSTRACTThe urgent need for sustainable transportation has highlighted the integration of solar photovoltaic (PV) panels into electric vehicle (EV) charging infrastructure. This review examines the benefits, challenges, and environmental impacts of this integration. The paper begins by exploring the role of large‐scale solar electric vehicles, featuring cost‐effective, flexible thin‐film solar cells embedded in vehicle body panels. Extensive simulations in various climates demonstrate their potential to address EV charging concerns, reduce range limitations, and manage intermittent energy generation. The review then focuses on Japan's leadership in renewable energy, analyzing the integration of PV power into future electricity systems. Scenario analysis reveals the synergy between renewables, EVs, and heat pumps, supported by smart control strategies, indicating a sustainable energy future for Japan. The final analysis shifts to the Netherlands, where integrating PV panels with workplace EV charging shows promise both economically and environmentally. Economic assessments confirm the feasibility of this approach, supported by installation methods and feed‐in tariffs. Overall, the review highlights the transformative potential of solar PV integration in EV charging infrastructure while acknowledging technical and grid integration challenges. It calls on researchers, policymakers, and industry stakeholders to collaborate in advancing sustainable, efficient, and environmentally friendly urban transportation systems.
Numerical Evaluation of Design Strategies for a Composite Wind Turbine Blade: Using Metallic Foams and Optimising Topology
Authors: Tüfekci Mertol , Koçak Onur , Özkan Yaren , Pir İnci , Tüfekci Ekrem 
Published: February 2025

ABSTRACTThis study investigates and assesses two different strategies for the design of wind turbine blades, consisting of two components: the external shell made of carbon fibre‐reinforced epoxy and the internal beam. The first strategy is based on designing the blade through the selection of the beam material. Aluminium and aluminium foam with different porosity levels are considered for the beam material. The moduli of elasticity of the foams were calculated using the Mori‐Tanaka approach and ranged from 70 GPa for solid aluminium to 23.3 GPa for foams with 50% porosity. Then, using these results, the finite element simulations under various loading conditions are performed. It is observed that increasing the foam porosity from 0% to 50% results in a 50% reduction in beam weight, with only a 35% decrease in the specific stiffness. The second strategy involves a topology optimisation of the internal beam to determine the most structurally efficient geometry for the blade through finite element analyses. Aluminium is considered the beam material for topology optimisation studies. The topology optimisation leads to a 53% reduction in the beam mass compared to the initial design, while maintaining performance metrics within acceptable limits. The mechanical behaviour of blades designed with these two strategies is investigated in eight different positions during a complete revolution in steady‐state. The results are compared to each other, as well as a blade with a balsa beam as a benchmark. By providing a comprehensive assessment and comparison, this study provides a better understanding of how the chosen design method affects blade performance and demonstrates the balance between weight reduction and structural efficiency.
Spontaneous conception and pregnancy outcomes after multi‐agent chemotherapy and high‐dose radiotherapy for pelvic Ewing sarcoma: Case report and literature review
Authors: Tosto Valentina , Prefumo Federico , Scala Carolina , Tallone Ramona , Garaventa Alberto , Podestà Maurizio , Maffeo Ilaria 
Published: February 2025

AbstractEwing sarcoma is an aggressive, rare bone and soft tissue malignancy, often affecting the long bones and pelvis. A woman was diagnosed with Ewing sarcoma of the left pelvis at 18 years of age. She underwent left paravesical lesion resection with ipsilateral ureteral reimplantation and received combined multi‐agent chemotherapy and high‐dose pelvic radiotherapy. A gonadotropin‐releasing hormone analog was administered to preserve ovarian function. The patient received oral contraceptives as hormone replacement therapy due to secondary amenorrhea. She spontaneously conceived after the withdrawal of oral contraceptives at 24 years. The pregnancy was complicated by early third‐trimester impaired fetal growth and preterm premature rupture of membranes at 32 weeks of pregnancy. Spontaneous preterm labor started and the patient delivered vaginally at 34 weeks, without any complications. Including our report, only 10 cases of pregnancy after pelvic Ewing sarcoma are reported in the literature. Pregnancy and delivery can be achieved after combined pelvic treatment for Ewing sarcoma, taking into account possible obstetric risks and complications. Complex bone surgery is associated with cesarean delivery, but previous high‐dose pelvic irradiation does not seem to affect mode of delivery. Our report provides further information on perinatal management, given the cases previously described.
Hypoxia inducible factor 3‐alpha promotes a malignant phenotype in colorectal cancer cells
Authors: Lopez‐Mejia Alejandro , Moreno‐Londoño Angela Patricia , Fonseca Camarillo Gabriela , Yamamoto‐Furusho Jesús Kazuo , Villanueva‐Herrero Juan Antonio , de Leon‐Rendón Jorge Luis , Castañeda Patlán Maria Cristina , Robles‐Flores Martha 
Published: February 2025

AbstractColorectal cancer (CRC) is the third most common cancer worldwide. Hypoxia is a hallmark of the tumor microenvironment, and cellular adaptation to it is primarily mediated by the family of Hypoxia‐inducible factors (HIFs) HIF‐1α, HIF‐2α, and HIF‐3α. However, in contrast to HIF‐1α and HIF‐2α, a specific role for HIF‐3α in cancer biology has not yet been clearly established. This research was aimed to elucidate the role of HIF‐3α in colon cancer. As reported previously for HIF‐1α and HIF‐2α, we found that HIF‐3α is also overexpressed under normoxic conditions in all cancer cell lines examined and in patient‐derived tumor tissue samples compared with non‐malignant cells and normal tissue, but remarkably, pulse‐chase experiments demonstrated that HIF‐3α displays high stability in cells compared with HIF‐1α and HIF‐2α. Progno Scan data analysis showed that overexpression of HIF‐3α correlated with a patient's lower survival rate and a poor prognosis in colon adenocarcinoma patients. Knockdown of HIF‐3α expression was carried out to investigate the effects derived from its silencing on malignant phenotype. We found a significative decrease in the Hypoxia Response Element (HRE) reporter transcriptional activity mediated by HIF‐3α and a reduction in cell viability under oxidative stress in colon cancer cells with HIF‐3α knockdown compared with control HIF‐3α expressing cells. In addition, HIF‐3α silencing also produced an increase in apoptotic rate, decreased clonogenic capacity, altered autophagy flux, and modulated the canonical Wnt/β pathway in an isoform‐dependent and cell context‐dependent manner in colon cancer cells. Overall, these data show that transcriptional activity mediated by HI3‐3α plays an essential role in promoting the malignant phenotype, cell survival, and resistance to cell death in CRC cells.
Increase Docking Score Screening Power by Simple Fusion With CNNscore
Authors: Liang Huicong , Xie Aowei , Hou Ning , Wei Fengjiao , Gao Ting , Li Jiajie , Gao Xinru , Shi Chuanqin , Xiao Gaokeng , Xu Ximing 
Published: February 2025

ABSTRACTScoring functions (SFs) of molecular docking is a vital component of structure‐based virtual screening (SBVS). Traditional SFs yield their inherent shortage for idealized approximations and simplifications predicting the binding affinity. Complementarily, SFs based on deep learning (DL) have emerged as powerful tools for capturing intricate features within protein‐ligand (PL) interactions. We here present a docking‐score fusion strategy that integrates pose scores derived from GNINA's convolutional neural network (CNN) with traditional docking scores. Extensive validation on diverse datasets has shown that by means of multiplying Watvina docking score by CNNscore demonstrates state‐of‐the‐art screening power. Furthermore, in a reverse practice, our docking‐score fusion technique was incorporated into the virtual screening (VS) workflow aimed at identifying inhibitors of the challenging target TYK2. Two promising hits with IC50 9.99 μM and 13.76 μM in vitro were identified from nearly 12 billion molecules.
Video review by utilizing asynchronous video communication platform
Authors: Otsuka Yuki , Mitsuda Eiko , Yamamoto Yukichika , Kato Atsushi , Soshi Mano , Higuchi Masaya , Obika Mikako , Otsuka Fumio , Hashimoto Tadayuki 
Published: February 2025

AbstractBackgroundVideo review is widely recognized as an effective method for teaching communication; however, it can increase educators' workload and learners' stress.MethodsWe utilized Tsucom, an online platform developed by BonBon, Inc., which enables asynchronous video communication instead of traditional styles. An 11‐min and 42‐s consultation video from a fifth‐year resident was uploaded, and 10 physicians provided 30 text‐based feedback.ResultsIn this pilot survey, the utility and ease of use were rated 4.4 and 4.1 out of 5, respectively.ConclusionsWhile asynchronous online video reviews provided flexibility and greater participation, challenges remain, and further trials and evaluations were deemed necessary.
Validity of the Uninjured Limb as a Control for Preoperative Assessment in Anterior Cruciate Ligament Reconstruction
Authors: Grimandi Ronan , Tissier Florine , Garetier Marc , Labban Julien , Gérard Romain , Courtois‐Communier Emmanuelle , Andro Christophe , Bisseriex Hélène , Gunepin François‐Xavier , Rannou Fabrice , Giroux‐Metges Marie‐Agnès 
Published: February 2025

ABSTRACTMonitoring muscle atrophy in patients undergoing anterolateral cruciate ligament reconstruction is pivotal for optimizing postoperative recovery. Conventionally, the uninjured contralateral limb serves as the control. However, its relevance in patients with prolonged physical activity hiatus due to knee instability remains uncertain. Our objectives were to compare limbs within a control group by assessing combined force measurements, cross‐sectional areas (CSAs), and neuromuscular activation. In addition, we compared the contralateral limb of the surgery group preoperatively to the control group. This prospective controlled study (evidence level 2) included 40 healthy subjects (HG) and 30 patients scheduled for ACL surgery (SG). Both groups underwent identical assessments. The two HG limbs were compared to establish the standard difference for all assessed variables, whereas SG contralateral limb was compared with the mean of the control limbs. For HG, the comparisons between limbs showed no significant differences in muscle strength, CSA area, or electromyographic parameters. Similarly, comparisons between the SG contralateral limb and the mean of HG limbs revealed no significant differences in isometric and dynamic strength for the quadriceps and hamstrings (2.5 ± 0.5 and 2.6 ± 0.9 N.m/kg, and 1.7 ± 0.3 and 1.7 ± 0.4 N.m/kg, respectively). Neuromuscular activation and fatigue patterns were also comparable between groups. CSAs discrepancies were attributed to differences in body mass index between groups. These findings indicate that the contralateral limb in ACL_injured patients is functionally similar to that of healthy controls, supporting its use as a valid reference for monitoring postoperative recovery. Trial Registration: NCT03200678
High‐throughput assessment of Nb, Co, Ti, and Al effects on microstructure and mechanical properties in wrought nickel‐based superalloys
Authors: Meng Haoyan , Huang Jin , Zhao Tianhao , Zhang Xiaoyu , Tong Yang , Qu Jinglong , Li Weidong , Jiang Liang , Meng Fanchao , Chen Shuying 
Published: February 2025

AbstractThe influence of Nb, Co, Ti, and Al on the microstructural evolution and mechanical properties of GH4061 superalloy was simultaneously investigated using diffusion multiple techniques combined with double aging heat treatment. Co exhibited the highest penetration depth with monotonic concentration decrease, significantly inhibiting the formation of needle‐like δ phase and reduced the precipitation size of the γ′ phase. Nb diffusion formed distinct layers with clear interfaces, promoting substantial γ′′ phase precipitation, while simultaneously enhancing hardness through solid solution strengthening. Ti and Al diffusion generated substantial diffusion layers containing Ti‐Ni enriched needle‐like η phases and enhanced γ′ phase growth, characterized by increased size and volume fraction compared to the base alloy. In contrast to the base alloy, this diffusion layer was devoid of phases enriched with Nb. Mechanical property analysis demonstrated that high concentrations of Nb, Al, and Ti enhanced alloy hardness through various strengthening mechanisms, whereas increased Co content diminished the size of the γ′ phase at the interface, resulting in reduced hardness. This high‐throughput experimental approach significantly reduced experimental workload while enabling detailed analysis of varying element concentrations on microstructure and properties.
Asymptotic Properties of a Stochastic Predator–Prey Model With a General Functional Response Driven by Dual Stochastic Perturbations
Authors: Souna Fethi 
Published: February 2025

ABSTRACTThis paper investigates a generalized stochastic predator‐prey model consisting of two differential equations with a general nonlinear functional response denoted as , driven by both standard Brownian motion and Lévy noise. Unlike prior research, the main objective of this manuscript is to investigate the long‐term behavior of the system while placing only mild assumptions on the functional response. Our analysis establishes the existence and uniqueness of a global positive solution. Moreover, we derive sufficient conditions for the extinction and persistence of the two species by employing novel threshold parameters. Notably, these outcomes are derived and substantiated using a Lévy‐type perturbation by not requiring that the Lévy noise be bounded; that is, we do not assume .
Zoledronic acid increases spine bone mass and prevents hip bone loss after bariatric surgery: a randomized placebo‐controlled study
Authors: Gam Søren , Lysdahlgaard Simon , Gram Bibi , Kusk Martin Weber , Hermann Anne Pernille , Juhl Claus Bogh , Hansen Stinus Gadegaard 
Published: February 2025

AbstractObjectiveThe aim of this study was to investigate the effects of zoledronic acid for the prevention of bone loss after bariatric surgery.MethodsIn this randomized, double‐blinded study, 59 patients undergoing Roux‐en‐Y gastric bypass or sleeve gastrectomy (mean [SD], age: 48.9 [6.3] years, BMI: 42.3 [5.3], 73% female) were randomly assigned (1:1) to receive either zoledronic acid (5 mg; intervention [INT]) or placebo (control [CON]) preoperatively. The primary endpoint was the change in spine volumetric bone mineral density (vBMD) at 12 months after surgery. Secondary outcomes included changes in hip and femoral neck vBMD and areal BMD.ResultsThe estimated mean treatment effects of zoledronic acid on the spine and total hip were 6.8 mg/cm3 (95% CI 1.9–11.7; p = 0.003) and 5.0 mg/cm3 (95% CI: 1.4–8.5; p = 0.006), respectively. Bone mass in the spine increased by 2.6% in INT, whereas no changes were observed in CON. Additionally, bone loss in the total hip was prevented in INT compared with CON (vBMD: −0.6% vs. −3.6%; p = 0.006).ConclusionsZoledronic acid increases bone mass in the spine and prevents bone loss in the hip region after bariatric surgery compared with placebo.
Effects of Surface‐Treated Nanomagnesia on the Electro‐Mechanical Properties of Polypropylene/Ethylene‐Propylene‐Diene Monomer Blends
Authors: Sharip Mohd Ridhuan Mohd , Lau Kwan Yiew , Noorden Zulkarnain Ahmad , Tan Chee Wei , Zaidel Dyg Norkhairunnisa Abang , Ching Kuan Yong 
Published: February 2025

ABSTRACTWith a global shift toward energy sustainability, power cable insulation materials vital for modern energy transmission have seen needs for improvements. In this regard, thermoplastic polypropylene (PP) blends offer exceptional thermal and electrical properties over conventional insulation materials. Notably, nanostructuration of PP blends can further enhance the electrical properties of PP blends, but the underlying physics governing nanostructured PP blends has yet to be systematically explored. The current work therefore evaluates the effects of surface‐treated nanomagnesia (MgO) on the electro‐mechanical properties of PP blended with 10 wt%, 20 wt%, and 30 wt% of ethylene‐propylene‐diene monomer (EPDM). The results show that blending PP with EPDM exhibits significantly improved mechanical properties, with the elongation‐at‐break increasing beyond 400%, albeit that the breakdown strength deteriorates by 34%. Significantly, adding surface‐treated MgO to the PP/EPDM blends improves the breakdown strength of the materials by up to 14% without compromising the elongation‐at‐break of the materials. The mechanisms governing the improved breakdown strength of the PP/EPDM/MgO nanocomposites over the PP/EPDM blend counterparts are explained through changes in the materials' structures. These findings provide fundamental insights into the structure–property relationship of nanostructured PP blends crucial for the development of PP‐based power cable insulation.
Environmental Flows Rapidly Increase Zooplankton Abundance in a Regulated Lowland River
Authors: O'Brien Lauren , Hitchcock James N. , Mitrovic Simon M. 
Published: February 2025

ABSTRACTZooplankton are important parts of the food web that support the survival of larval fish in floodplain rivers. Zooplankton abundance and community structure are sensitive to flow‐driven changes in the environment, which have been heavily impacted by river regulation with dams. Environmental flows (e‐flows) are managed dam releases designed to restore a degree of natural ecological functioning to regulated rivers. Native fish spawning can be triggered by e‐flows, but it is not well understood whether these flows can stimulate instream zooplankton production in an appropriate timeframe to support feeding by fish larvae in their first weeks of life. This study aimed to investigate the immediate and longer‐term impacts of a planned dam release during the drought of 2018 in the Macquarie–Wambuul River of New South Wales, Australia, on the abundance of zooplankton and associated environmental variables. Dissolved organic carbon, nitrogen oxides (NOx) and chlorophyll a increased significantly at the onset of the e‐flow. The zooplankton community was dominated by Cladocera (also named Diplostraca). The significant drivers of zooplankton community structure were NOx, temperature and river level. The start of the e‐flow coincided with a significant increase in cladoceran densities, which resulted in up to 36.2 × 109 ± 1.5 × 109 Cladocera d−1 being exported through the study sites. Increased zooplankton exports were maintained for at least 6 weeks after the onset of the e‐flow. These findings demonstrate that e‐flows during drought can stimulate increased zooplankton abundance within appropriate timeframes to support the survival of native fish larvae.
Bulk Magnetic Properties Arise from Micron‐Sized Supraparticle Interactions and Can be Modified on the Nanoscale
Authors: Wolf Andreas , Heinlein Markus , Kent Noah , Müssig Stephan , Mandel Karl 
Published: February 2025

AbstractMagnetic supraparticles (SPs) can be employed as micron‐sized particulate additives in arbitrary objects to serve as ID‐tag or recorder of environmental triggers. Combined with magnetic particle spectroscopy (MPS), which enables read‐out of the magnetic information in ambient conditions within seconds, magnetic SPs represent a powerful approach to equip materials with information. The encoded information relies on magnetic interactions within the SPs (intra‐SP interactions) of chosen nanoparticles (NPs). However, possible magnetic interactions between SPs (inter‐SP interactions), that might alter the MPS signal as well, have been neglected so far. Herein, it is elucidated that significant inter‐SP interactions exist and that they can be tailored via adjustments in the SP structure, i.e., by defined adjustments of their intra‐interaction as revealed by 3D‐MuMax simulations and experiments in viscous fluids. Superparamagnetic iron oxide nanoparticle‐based SP powders with strong inter‐SP interactions exhibit significantly different MPS signals compared to their state after being incorporated into a matrix. Powders with weak inter‐SP interactions (achieved by integration of non‐magnetic SiO2 nanoparticles) show almost no signal change before and after incorporation. Both extremes of inter‐SP interactions can be beneficial for various application scenarios and can be tailored on the nano‐scale due to the interdependency of intra‐ and inter‐SP interactions.