bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changing patterns in reporting and sharing of review data in systematic reviews with meta-analysis of the effects of interventions: cross sectional meta-research study
Authors: Nguyen Phi-Yen , Kanukula Raju , McKenzie Joanne E , Alqaidoom Zainab , Brennan Sue E , Haddaway Neal R , Hamilton Daniel G , Karunananthan Sathya , McDonald Steve , Moher David , Nakagawa Shinichi , Nunan David , Tugwell Peter , Welch Vivian A , Page Matthew J 
Published: November 2022

Abstract

Objectives
To examine changes in completeness of reporting and frequency of sharing data, analytical code, and other review materials in systematic reviews over time; and factors associated with these changes.

Design
Cross sectional meta-research study.

Population
Random sample of 300 systematic reviews with meta-analysis of aggregate data on the effects of a health, social, behavioural, or educational intervention. Reviews were indexed in PubMed, Science Citation Index, Social Sciences Citation Index, Scopus, and Education Collection in November 2020.

Main outcome measures
The extent of complete reporting and the frequency of sharing review materials in the systematic reviews indexed in 2020 were compared with 110 systematic reviews indexed in February 2014. Associations between completeness of reporting and various factors (eg, self-reported use of reporting guidelines, journal policies on data sharing) were examined by calculating risk ratios and 95% confidence intervals.

Results

Several items were reported suboptimally among 300 systematic reviews from 2020, such as a registration record for the review (n=113; 38%), a full search strategy for at least one database (n=214; 71%), methods used to assess risk of bias (n=185; 62%), methods used to prepare data for meta-analysis (n=101; 34%), and source of funding for the review (n=215; 72%). Only a few items not already reported at a high frequency in 2014 were reported more frequently in 2020. No evidence indicated that reviews using a reporting guideline were more completely reported than reviews not using a guideline. Reviews published in 2020 in journals that mandated either data sharing or inclusion of data availability statements were more likely to share their review materials (eg, data, code files) than reviews in journals without such mandates (16/87 (18%)
v
4/213 (2%)).

Conclusion
Incomplete reporting of several recommended items for systematic reviews persists, even in reviews that claim to have followed a reporting guideline. Journal policies on data sharing might encourage sharing of review materials.
Study protocol for a randomised placebo controlled trial of platelet-rich plasma injection to prevent post-traumatic knee osteoarthritis after anterior cruciate ligament reconstruction
Authors: Momoi Yasumasa , Saita Yoshitomo , Nagao Masashi , Kobayashi Yohei , Nakajima Ryosuke , Uchino Sayuri , Wakayama Takanori , Nishio Hirofumi , Fukusato Shin , Wakana Suguru , Tomura Jun , Kobayashi Keiji , Yoshida Keiichi , Kaneko Haruka , Kubota Mitsuaki , Ishijima Muneaki 
Published: November 2022

IntroductionThe elevated cytokine levels in patients suffering from anterior cruciate ligament (ACL) rupture may lead to acute post-traumatic arthritis (APTA) and post-traumatic osteoarthritis (PTOA). Due to its chondrogenerative and anti-inflammatory effect, platelet-rich plasma (PRP) therapy is expected to show a positive outcome in APTA and PTOA. The proposed trial aims to quantitatively measure the efficacy of PRP injection in arresting post-traumatic cartilage degeneration among patients after ACL reconstruction.Methods and analysisThis will be a single-blind, randomised, prospective, controlled clinical trial designed following the Consolidated Standards of Reporting Trials guidelines. After ACL reconstruction, 80 patients will be randomised to receive either leucocyte-poor PRP injection after joint aspiration or a placebo control group receiving only joint aspiration. Participants (age 20–49 years) will be those who have undergone ACL reconstruction within the past 2 weeks with a body mass index<35 and Kellgren Lawrence osteoarthritis grade<2. The primary outcome will include MRI-T2 values of knee cartilage at 6 months. The secondary outcomes will include pain assessment by Visual Analogue Scale, Knee injury and Osteoarthritis Outcome Score, blood and urine test, physical findings, measurements for muscle strength and joint stability.Ethics and disseminationThe study was approved by The Independent Ethics Committee for Clinical Trials of the Japanese Association for the Promotion of State-of-the-Art Medicine. Results of the trial and each of the outcomes will be shared via conferences and publication in a peer-reviewed journal.Trial registration numberjRCTb030200391.
Identifying the sectors involved in the European public health emergency preparedness and response: a systematic review
Authors: Kengne Kamga L S , Voordouw A C G , de Vries M C , Belfroid E , Koopmans M , Timen A 
Published: November 2022

ObjectivesA systematic review was conducted with the aims of identifying sectors mentioned in the public health emergency preparedness and response (PHEPR) literature and mapping the involvement of those sectors in the seven PHEPR cycle domains.SettingA detailed search strategy was conducted in Embase and Scopus, covering the period between 1 January 2005 and 1 January 2020.MethodsPublished articles focusing on preparedness for and/or response to public health emergencies of multiple origins on the European continent were included. The frequency with which predetermined sectors were mentioned when describing collaboration during the preparedness and response cycle was determined.ResultsThe results show that description of the involvement of sectors in PHEPR in general and collaboration during PHEPR is predominantly confined to a limited number of sectors, namely ‘Governmental institutions’, ‘Human health industry’, ‘Experts’ and ‘Civil Society’. Description is also limited to only three domains of the PHEPR cycle, namely ‘Risk and crisis management’, ‘Pre-event preparations and governance’ and ‘Surveillance’.ConclusionsOptimal preparedness and response require predefined collaboration with a broader scope of partners than currently seems to be the case based on this literature review. We recommend considering these outcomes when planning multisectoral collaboration during preparedness and response, as well as the need to further operationalise the term ‘multisectoral collaboration’ during PHEPRs.PROSPERO registration numberPROSPERO with registration number 176 331.
Heterogeneity of Zika virus exposure and outcome ascertainment across cohorts of pregnant women, their infants and their children: a metadata survey
Authors: Carabali Mabel , Maxwell Lauren , Levis Brooke , Shreedhar Priya 
Published: November 2022

ObjectivesTo support the Zika virus (ZIKV) Individual Participant Data (IPD) Consortium’s efforts to harmonise and analyse IPD from ZIKV-related prospective cohort studies and surveillance-based studies of pregnant women and their infants and children; we developed and disseminated a metadata survey among ZIKV-IPD Meta-Analysis (MA) study participants to identify and provide a comprehensive overview of study-level heterogeneity in exposure, outcome and covariate ascertainment and definitions.SettingCohort and surveillance studies that measured ZIKV infection during pregnancy or at birth and measured fetal, infant, or child outcomes were identified through a systematic search and consultations with ZIKV researchers and Ministries of Health from 20 countries or territories.ParticipantsFifty-four cohort or active surveillance studies shared deidentified data for the IPD-MA and completed the metadata survey, representing 33 061 women (11 020 with ZIKV) and 18 281 children.Primary and secondary outcome measuresStudy-level heterogeneity in exposure, outcome and covariate ascertainment and definitions.ResultsMedian study sample size was 268 (IQR=100, 698). Inclusion criteria, follow-up procedures and exposure and outcome ascertainment were highly heterogenous, differing meaningfully across regions and multisite studies. Enrolment duration and follow-up for children after birth varied before and after the declaration of the Public Health Emergency of International Concern (PHEIC) and according to the type of funding received.ConclusionThis work highlights the logistic and statistical challenges that must be addressed to account for the multiple sources of within-study and between-study heterogeneity when conducting IPD-MAs of data collected in the research response to emergent pathogens like ZIKV.
Factors associated with small-for-gestational-age births among preterm babies born <2000 g: a multifacility cross-sectional study in Ethiopia
Authors: Debere Mesfin K , Haile Mariam Damen , Ali Ahmed , Mekasha Amha , Chan Grace J 
Published: November 2022

ObjectivesThis study aimed to determine the prevalence of small-for-gestational-age (SGA) and appropriate-for-gestational-age (AGA); compare variations in multiple risk factors, and identify factors associated with SGA births among preterm babies born <2000 g.DesignCross-sectional study.SettingThe study was conducted at five public hospitals in Oromia Regional State and Addis Ababa City Administration, Ethiopia.Participants531 singleton preterm babies born <2000 g from March 2017 to February 2019.Outcome measuresBirth size-for-gestational-age was an outcome variable. Birth size-for-gestational-age centiles were produced using Intergrowth-21st data. Newborn birth size-for-gestational-age below the 10th percentile were classified as SGA; those>10th to 90th percentiles were classified as AGA; those >90th percentiles, as large-for-gestational-age, according to sex. SGA and AGA prevalence were determined. Babies were compared for variations in multiple risk factors.ResultsAmong 531 babies included, the sex distribution was: 55.44% males and 44.56% females. The prevalences of SGA and AGA were 46.14% and 53.86%, respectively. The percentage of SGA was slightly greater among males (47.62%) than females (44.30%), but not statistically significant The prevalence of SGA was significantly varied between pre-eclamptic mothers (32.42%, 95% CI 22.36% to 43.22%) and non-pre-eclamptic mothers (57.94%, 95% CI 53.21% to 62.54%). Mothers who had a history of stillbirth (adjusted OR (AOR) 2.96 95% CI 1.04 to 8.54), pre-eclamptic mothers (AOR 3.36, 95% CI 1.95 to 5.79) and being born extremely low birth weight (AOR 10.48, 95% CI 2.24 to 49.02) were risk factors significantly associated with SGA in this population.ConclusionPrevalence of SGA was very high in these population in the study area. Maternal pre-eclampsia substantially increases the risk of SGA. Hence, given the negative consequences of SGA, maternal and newborn health frameworks must look for and use evidence on gestational age and birth weight to assess the newborn’s risks and direct care.
Association between grass, tree and weed pollen and asthma health outcomes in Adelaide, South Australia: a time series regression analysis
Authors: Nitschke Monika , Dear Keith Brian Gordon , Venugopal Kamalesh , Lyne Katrina Margaret Rose , Jersmann Hubertus Paul Anton , Simon David Leslie , Spurrier Nicola 
Published: November 2022

ObjectivesWe aim to establish daily risk estimates of the relationships between grass, tree and weed pollen and asthma health outcomes.DesignTime series regression analysis of exposure and health outcomes using interaction by month to determine risk estimates all year round.SettingMetropolitan Adelaide, South Australia.ParticipantsHealth outcomes for asthma are based on 15 years of hospital admissions, 13 years emergency presentations and ambulance callouts. In adults (≥18 years), there were 10 381 hospitalisations, 26 098 emergency department (ED) presentations and 11 799 ambulance callouts and in children (0–17 years), 22 114, 39 813 and 3774, respectively.Outcome measuresThe cumulative effect of 7 day lags was calculated as the sum of the coefficients and reported as incidence rate ratio (IRR) related to an increase in 10 grains of pollen/m3.ResultsIn relation to grass pollen, children and adults were disparate in their timing of health effects. Asthma outcomes in children were positively related to grass pollen in May, and for adults in October. Positive associations with weed pollen in children was seen from February to May across all health outcomes. For adults, weed pollen-related health outcomes were restricted to February. Adults were not affected by tree pollen, while children’s asthma morbidity was associated with tree pollen in August and September. In children, IRRs ranged from 1.14 (95% CI 1.06 to 1.21) for ED presentations for tree pollen in August to 1.98 (95% CI 1.06 to 3.72) for weed pollen in February. In adults, IRRs ranged from 1.28 (95% CI 1.01 to 1.62) for weed pollen in February to 1.31 (95% CI 1.08 to 1.57) for grass pollen in October.ConclusionMonthly risk assessment indicated that most pollen-related asthma health outcomes in children occur in the colder part of the year, while adults are affected in the warm season. The findings indicate a need for year-round pollen monitoring and related health campaigns to provide effective public health prevention.
Blindness in infants presenting with advanced and untreated ROP: a single-centre study in Pakistan
Authors: Moin Muhammad , Mian Lubna Siddiq , Gilbert Clare , Irfan Abdullah , Mian Umar K 
Published: November 2022

ABSTRACTPurposeTo describe the ocular features and characteristics of young children presenting with advanced, untreated retinopathy of prematurity and to determine appropriate screening guidelines for retinopathy of prematurity (ROP) in Pakistan.Material and methodsA retrospective case series of young children with stage5A or 5B or cicatricial changes (4B or 4A ROP) was undertaken in the Department of Ophthalmology, Lahore General Hospital, Lahore, Pakistan, from August 2017 to July 2019. Information was obtained from interviewing parents and from neonatal care discharge summaries, if available. An assessment of visual function and a dilated fundus examination were performed.Results51 children presented at mean age of 9.7 (1.5–36) months. Their mean gestational age (GA) was 28.84 (26–38) weeks, and mean birth weight (BW) was 1229 (800–2100) g. Four children (7.8%) had a GA of >31 weeks plus a BW of >1501 g. 40 (76.4%) children were blind and 11 (23.6%) had impaired vision. Sixty-five eyes (63.7%) had stage 5B; 13 (12.7%) eyes had stage 5A; 18 (17.6%) had falciform macular folds (4B ROP) and 6 eyes (5.9%) had macular dragging (4A ROP). 39 (76.5%) children had bilateral stage 5A/5B. Half (47%) of the children lived outside the capital city of Lahore, and 15 came from small cities (population <1 million).ConclusionThe third epidemic of blindness due to ROP has arrived in Pakistan, and premature babies are going blind even in smaller cities. Initial screening guidelines of a GA of ≤35 weeks and BW of ≤2000 g seem reasonable. There is an urgent need to improve the quality of neonatal care and to increase the coverage of ROP screening and treatment services across the country.
Tenecteplase versus alteplase before mechanical thrombectomy: experience from a US healthcare system undergoing a system-wide transition of primary thrombolytic
Authors: Hendrix Philipp , Collins Malie K , Griessenauer Christoph J , Goren Oded , Melamed Itay , Weiner Gregory M , Dalal Shamsher S , Kole Matthew J , Noto Anthony , Schirmer Clemens M 
Published: November 2022

BackgroundTenecteplase (TNK) is a genetically modified variant of alteplase (TPA) and has been established as a non-inferior alternative to TPA in acute ischemic stroke (AIS). Whether TNK exerts distinct benefits in large vessel occlusion (LVO) AIS is still being investigated.ObjectiveTo describe our first-year experience after a healthcare system-wide transition from TPA to TNK as the primary thrombolytic.MethodsPatients with AIS who received intravenous thrombolytics between January 2020 and August 2022 were retrospectively reviewed. All patients with LVO considered for mechanical thrombectomy (MT) were included in this analysis. Spontaneous recanalization (SR) after TNK/TPA was a composite variable of reperfusion >50% of the target vessel territory on cerebral angiography or rapid, significant neurological recovery averting MT. Propensity score matching (PSM) was performed to compare SR rates between TNK and TPA.ResultsA total of 148 patients were identified; 51/148 (34.5%) received TNK and 97/148 (65.5%) TPA. The middle cerebral arteries M1 (60.8%) and M2 (29.7%) were the most frequent occlusion sites. Baseline demographics were comparable between TNK and TPA groups. Spontaneous recanalization was significantly more frequently observed in the TNK than in the TPA groups (unmatched: 23.5% vs 10.3%, P=0.032). PSM substantiated the observed SR rates (20% vs 10%). Symptomatic intracranial hemorrhage, 90-day mortality, and functional outcomes were similar.ConclusionsThe preliminary experience from a real-world setting demonstrates the effectiveness and safety of TNK before MT. The higher spontaneous recanalization rates with TNK are striking. Additional studies are required to investigate whether TNK is superior to TPA in LVO AIS.
Comprehensive nationwide incidence and prevalence trends of atrial fibrillation in Finland
Authors: Lehto Mika , Haukka Jari , Aro Aapo , Halminen Olli , Putaala Jukka , Linna Miika , Mustonen Pirjo , Kinnunen Janne , Kouki Elis , Niiranen Jussi , Luojus Alex , Tiili Paula , Itäinen-Strömberg Saga , Hartikainen Juha , Airaksinen Juhani K E 
Published: November 2022

ObjectiveAtrial fibrillation (AF) is a worldwide healthcare challenge owing to population ageing. In this study, we assessed the current trends in the incidence and prevalence of AF for the first time in an unselected, nationwide population.MethodsIn the Finnish Anticoagulation in Atrial Fibrillation study, we gathered comprehensive data including all primary, secondary and tertiary healthcare visits and drug reimbursement from national healthcare registers to identify all patients with incident AF between 2004 and 2018 in Finland. Incident AF was defined as new-onset AF occurring after 2007. Time trends for the incidence and prevalence of AF were calculated and stratified by sex and age.ResultsA total of 411 387 patients with AF diagnosis were documented in Finland during 2004–2018. In 2018, the incidence and prevalence of AF in the total Finnish population were 469/100 000 and 4.1%, respectively. The incidence of new-onset AF in the adult population (≥20 years) increased from 471/100 000 in 2007 to 604/100 000 in 2018, but the age-adjusted incidence remained stable. The prevalence of AF increased in the adult population from 2.5% to 5.2%, and was higher in men than in women (5.9% vs 4.6%, p<0.001). The incidence and prevalence of AF increased with age and were 3194/100 000 and 23.4% in patients older than 75 years.ConclusionsBased on comprehensive nationwide data including primary care, we observed an increasing incidence and prevalence of AF over time. This increase was strongly age-dependent with the age-standardised incidence remaining stable during 2007–2018.Trial registration numberNCT04645537.
Two particles interacting via a contact interaction on $$S^2$$
Authors: Schuh Dominic , Luu Thomas 
Published: November 2022

AbstractWe consider two particles interacting via a contact interaction that are constrained to a sphere, or $$S^2$$

S
2

. We determine their spectrum to arbitrary precision and for arbitrary angular momentum. We show how the non-inertial frame leads to non-trivial solutions for different angular momenta. Our results represent an extension of the finite-volume Lüscher formulas but now to a non-trivial geometry. We apply our results to predict the spectrum of select two-nucleon halo nuclei and compare with experimental results.
Deep Learning with Game Theory Assisted Vertical Handover Optimization in a Heterogeneous Network
Authors: Kayikci Safak , Unnisa Nazeer , Das Anupam , Kanna S. K. Rajesh , Murthy Mantripragada Yaswanth Bhanu , Preetha N. S. Ninu , Brammya G. 
Published: November 2022

Problem: In next-generation networks, users can optimize or tune their preferences with a seamless transfer of diverse access methodologies for maximizing the Quality of Service (QoS) and cost savings. In these heterogeneous wireless environments, users are prepared with several multimode wireless devices for maximizing media services through several access networks. Such networks may vary regarding energy usage, available bandwidth, technology, coverage range, monetary cost, etc. In recent days, vertical handover has attained higher performance owing to the improvements in mobility models through adopting the Fourth Generation (4G) technologies. On the other hand, these improvements are restricted to some cases, so, it does not offer support for generic mobility. Consequently, diverse strategies were implemented by considering these mobility models. However, it suffers from improper network selection, late and too-early handovers, repeated handovers, high packet loss, etc. Aim: This paper tackles the problem of vertical handover problem in the heterogeneous network using deep learning with game theory. Methods: The proposed model develops a non-cooperative game approach, in which all base stations compete selfishly to transmit at higher power. The overall performance in terms of throughput, handover, energy consumption, and load balancing is attained by optimizing the transmission power by the game theory. For performing this model, the required data like path loss, SINR, data rate, load, etc are generated by the deep learning called Recurrent Neural Network (RNN). Results: From the simulation findings, the handoff probability of the recommended RNN+Game Theory is correspondingly secured at 6.9%, 22.6%, and 8.2% superior to TOPSIS, ABC-PSO, and game theory when taking the time like 5 secs for user velocity as 30 km/h. Conclusion: Results show that the proposed game theoretical approach with deep learning provides a throughput enhancement while reducing the power consumption, in addition, to minimizing the unnecessary handover and balancing the load between base stations.
VLDB Scalable Data Science Category
Authors: Kumar Arun , Halevy Alon , Tatbul Nesime 
Published: November 2022

As part of the International Conference on Very Large Data Bases (VLDB) 2021 / Proceedings of the VLDB Endowment Volume 14, a new Research Track category named Scalable Data Science (SDS) was launched [2, 6]. The goal of SDS is to attract cutting-edge and impactful real-world work in the scalable data science arena to enhance the impact and visibility of the VLDB community on data science practice, spur new technical connections, and inspire new follow-on research. The inaugural year proved to be successful, with numerous interesting papers from a wide cross section of both industry and academia, spanning several data science topics, and originating from several countries around the world.
In this report, we reflect on the inaugural year of SDS with some statistics on both submissions and accepted papers, SDS invited talks, and our observations, lessons, and tips as inaugural Associate Editors for SDS. We hope this article is helpful to future authors, reviewers, and organizers of SDS, as well as other interested members of the wider database / data management community and beyond.