bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parameters Affecting Worst‐Case Gradient‐Field Heating of Passive Conductive Implants
Authors: Bassen Howard , Zaidi Tayeb 
Published: July 2022

BackgroundTesting MRI gradient‐induced heating of implanted medical devices is required by regulatory organizations and others. A gradient heating test of the ISO 10974 Technical Specification (TS) for active implants was adopted for this study of passive hip implants. All but one previous study of hip implants used nonuniform gradient exposure fields in clinical scanners and reported heating of less than 5 °C. This present study adapted methods of the TS, addressing the unmet need for identifying worst‐case heating via exposures to uniform gradient fields.PurposeTo identify gradient‐field parameters affecting maximum heating in vitro for a hip implant and a cylindrical titanium disk.Study TypeComputational simulations and experimental validation of induced heating.PhantomTissue‐simulating gel.Field Strength42 T/s RMS, sinusoidal, continuous B fields with high spatial uniformityAssessmentHip implant heating at 1–10 kHz, via computational modeling, validated by limited point measurements. Experimental measurements of exposures of an implant at 42 T/s for 4, 6, and 9 kHz, analyzed at 50, 100, and 150 seconds.Statistical TestsOne sample student's t‐test to assess difference between computational and experimental results. Experimental vs. computational results were not significantly different (p < 0.05).ResultsMaximum simulated temperature rise (10‐minute exposure) was 10 °C at 1 kHz and 0.66 °C at 10 kHz. The ratio of the rise for 21 T/s vs. 42 T/s RMS was 4, after stabilizing at 50 seconds (dB/dt ratio squared).Data ConclusionsHeating of an implant is proportional to the frequency of the B field and the implant's cross‐sectional area and is greater for a thickness on the order of its skin depth. Testing with lower values of dB/dt RMS with lower cost amplifiers enables prediction of heating at higher values for dB/dt squared (per ISO TS) with identical frequency components and waveforms, once thermal equilibrium occurs.Evidence Level1Technical EfficacyStage 1
Investigation of the effect of COVID‐19 on sperm count, motility, and morphology
Authors: Aksak Tiinçe , Satar Deniz A. , Bağci Rıdvan , Gülteki̇n Efdal O. , Coşkun Arzu , Demi̇rdelen Umut 
Published: July 2022

AbstractSevere acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is a single‐stranded RNA virus that causes many diseases such as respiratory diseases, cardiovascular diseases, and gastrointestinal diseases. Although it has been shown that the angiotensin‐converting enzyme 2 receptor, which has a high affinity for the SARS‐CoV‐2 is mostly expressed in the lungs, it is also expressed especially in the cells of the testicular tissue. Although there are studies showing the effect of SARS‐CoV‐2 on spermatogenesis, the effects of COVID‐19 on sperm count, motility, and morphology are still unclear. The aim of this study is to investigate changes in sperm quality in men who had recovered and never had COVID‐19, therefore semen samples were analyzed from all individuals in the patient and control groups aged 20–50 years who agreed to participate in the study and voluntary in SBU Ministry of Health Adana City Training and Research Hospital. (Toros University Ethics Committee Decision Number: 1433, Date: April 15, 2021) (Adana Provincial Health Directorate Ethics Commission Decision dated May 27, 2021/5). Two groups were selected (100 men had and recovered from COVID‐19, and 100 men never had COVID‐19) spermiograms from both groups were analyzed in accordance with the World Health Organization standards. The sperm concentration of the COVID‐19 negative group was significantly higher than those in the COVID‐19 positive group. No statistically significant difference was detected between the groups for sperm motility and morphology. It was observed that men with COVID‐19 had decreased sperm concentrations suggesting that COVID‐19 may have a negative effect on male fertility. However, in the long term, more comprehensive studies with a large sample size are needed to understand better the changes in sperm concentration.
Integration of charging station to the smart grid power network by using robust immune feedback adaptive and Rao optimization approaches
Authors: Jaraniya Dulichand , Kumar Shailendra 
Published: July 2022

AbstractThe adoption of electrical vehicles (EVs) is nowadays a center of attraction, which reduces the carbon footprint and adds to the economic growth of a country. However, providing a proper charging facility to the customers is still a challenging task. This paper presents the mix (AC‐DC) charging station (CS) integrated with the PV array and the smart distribution grid. The acceleration of the EV causes the power quality burden on the grid and this can be taken care of by using advanced adaptive controls. In this paper, the control strategy used for the CS is the immune feedback‐based adaptive (IFA) control technique. It reduces the ripples in the fundamental load current extraction under steady‐state and produces fast response under dynamic conditions and helps to synchronize CS with the grid. The multi‐functional capabilities of the CS are presented with different voltage levels DC fast off‐board chargers and AC onboard slow chargers. Moreover, the Rao optimization technique is utilized to select the gains for the cascaded proportional‐integral (PI) controllers which are used to regulate the DC bus voltage and battery charging/discharging currents. The optimized fitness values of integral time square error (ITSE) by using Rao1, Rao2, and Rao3 techniques are 297.341, 285.023, and 282.924 respectively. The simulated and test results depict the efficacy of the CS. Moreover, the mixed charging facilities with multi DC fast chargers avoid the rush and burden on the grid, which reduces the power outage across the load and rapidly rising energy cost.
[18F]FDG brain uptake of C57Bl/6 male mice is affected by locomotor activity after cocaine use: A small animal positron emission tomography study
Authors: Spelta Lidia Emmanuela Wiazowski , Real Caroline Cristiano , Buchpiguel Carlos Alberto , de Paula Faria Daniele , Marcourakis Tania 
Published: July 2022

AbstractWe verified if cocaine‐induced peripheral activation might disrupt [18F]FDG brain uptake after a cocaine challenge and suggested an optimal protocol to measure cocaine‐induced brain metabolic alterations in mice. C57Bl/6 male mice were injected with [18F]FDG and randomly separated into three groups. Groups 1 and 2 were kept conscious after [18F]FDG administration and after 5 min received saline or cocaine (20 mg/kg). The animals in group 1 (n = 5) were then evaluated in the open field for 30 min and those from group 2 (n = 6) were kept alone in a home cage for the same period. Forty‐five minutes after [18F]FDG administration, images were acquired for 30 min. Group 3 (n = 6) was kept anesthetized and image acquisition started immediately after tracer injection, for 75 min. Saline (Day 1) or cocaine (Day 2) was injected 5 min after starting acquisition. Another set of animals (n = 5) were treated with cocaine every other day for 10 days or saline (n = 6) and were scanned with the dynamic protocol to verify its efficacy. [18F]FDG uptake increased after cocaine administration when compared to baseline only in animals kept under anesthesia. No brain effect of cocaine was observed in animals submitted to the open field or kept in the home cage. The use of anesthesia is essential to visualize cocaine‐induced changes in brain metabolism by [18F]FDG PET, providing an interesting preclinical approach to investigate naïve subjects and enabling a bidirectional translational science approach for better understanding of cocaine use disorder.
Histopathological characteristics of larynx in hypothyroidism in an experimental rabbit model
Authors: Iravani Kamyar , Golkhar Behnaz , Azarpira Negar , Kohandel‐Shirazi Mahsa , Vahedi Mahjoob 
Published: July 2022

AbstractObjectiveHypothyroidism has a significant effect on the patients' voices. This study evaluated the histopathological characteristics of larynx following hypothyroidism in an experimental rabbit model.MethodsEleven male Dutch rabbits were included. Methimazole‐induced hypothyroidism was done for nine rabbits. The remaining two rabbits were assigned as controls. Six weeks after starting methimazole, a histological examination was performed with parameters of inflammation, ulceration, hemorrhage, and thickness of epithelium, Reinke's space, vocal ligament, thyroarytenoid muscle, collagen deposition, and periodic acid‐Schiff (PAS)‐positive materials, as well as confirmation of hypothyroidism by T4 measurement.ResultsHistologic examination showed a significant thickening of epithelium, Reinke's space, vocal ligament, and collagen PAS‐positive materials deposition in hypothyroid rabbits (p < .05). There was significant reduction in thyroarytenid muscle thickness (p < .05). Inflammation, ulceration, and bleeding were not significantly different between hypothyroid and control rabbits' laryngeal specimens.ConclusionHypothyroidism causes significant changes in the laryngeal tissues. Thickening of epithelium, Reinke's space, vocal ligament, collagen, PAS‐positive materials, and reduced thickness of thyroarytenoid muscle are the major findings of this study.
Quantum Fluctuations and Lineshape Anomaly in a High‐β Silver‐Coated InP‐Based Metallic Nanolaser
Authors: Koulas‐Simos Aris , Buchgeister Joel , Drechsler Monty L. , Zhang Taiping , Laiho Kaisa , Sinatkas Georgios , Xu Jialu , Lohof Frederik , Kan Qiang , Zhang Ruikang K. , Jahnke Frank , Gies Christopher , Chow Weng W. , Ning Cun‐Zheng , Reitzenstein Stephan 
Published: July 2022

AbstractMetallic nanocavity lasers provide important technological advancement toward even smaller integrable light sources. They give access to widely unexplored lasing physics in which the distinction between different operational regimes, like those of thermal or coherent light emission, becomes increasingly challenging upon approaching a device with a near‐perfect spontaneous‐emission coupling factor . In fact, quantum‐optical studies have to be employed to reveal a transition to coherent emission in the intensity fluctuation behavior of nanolasers when the input–output characteristic appears thresholdless for nanolasers. Here, a new indicator for lasing operation in high‐ lasers is identified by showing that stimulated emission can give rise to a lineshape anomaly manifested as a transition from a Lorentzian to a Gaussian component in the emission linewidth that dominates the spectrum above the lasing threshold.
Development and Characterization of Complementary Polymer Network Bioinks for 3D Bioprinting of Soft Tissue Constructs
Authors: Song Shaoshuai , Li Yuxuan , Huang Jie , Zhang Zhijun 
Published: July 2022

AbstractThe development of 3D bioprinting has been hindered by a narrow “biofabrication window” with a limited variety of feasible bioinks which are compatible with both high printability and well cytocompatibility. Herein, a generalizable strategy using complementary polymer network (CPN) bioinks is developed in the current study, to address the conflict between the printability and cytocompatibility of bioinks in extrusion 3D bioprinting, especially for the manufacture of soft tissue constructs. In this strategy, CPN bioinks are formed though mixing two interpenetrated polymer networks, one of which is a photocrosslinkable polymer network, and the other is a dynamic polymer network crosslinked by reversible covalent linkage, thereby endowed with well reversible thixotropy. Compatible with well printability, shape fidelity, and cytocompatibility, the utilization of CPN bioinks provides a viable solution for extrusion 3D bioprinting of photocrosslinkable biomaterials at a low concentration, thus suitable for soft tissue construct fabrication. Briefly, this study is testified to be a successful attempt to extend the bioink diversity within the “biofabrication window,” and offers a novel insight into designing more feasible bioinks based on their special rheological properties, for further tissue engineering and biomedicine application.
Broadband miniaturized 180° phase shifter based on symmetric coupling structure
Authors: Zhang Zhe , Guan Meng , An Kang , Chen Aixin 
Published: July 2022

AbstractAn electronically reconfigurable wideband 180° phase switch using microstrip–slotline transitions is proposed. Multilayer structure with microstrips on the bottom and top layers, slotline on the middle layer confirm the broadband transmission. Taking advantage of the symmetry of the transition, only two p–i–n diodes are integrated on the top microstrip layer to achieve a 0°/180° phase reconfiguration. Miniaturized design is achieved with a size of 0.26λg × 0.16λg. The measured results are in good agreement with the simulated results, which show less than 5° phase deviation and less than 1.5 dB insertion loss across the band 0.68–2.5 GHz.
Dual rhombic loop‐based frequency selective surfaces for X‐band applications
Authors: Verma Ashish Kumar , Singhal Rahul 
Published: July 2022

AbstractDual rhombic loop (DRL) based low‐cost X‐band frequency selective surfaces (FSSs) with stopband characteristics are presented in this study. Orthogonally oriented arrays of rhombic loop pairs are printed back‐to‐back (BTB) on both sides of dielectric substrate to achieve wide stopband characteristics with stable response under oblique incidences. The nonlinearities in the reflection phase of BTB DRL printed FSSs are compensated by printing orthogonally oriented rhombic loop pairs on the same side of the substrate. Merging orthogonally oriented rhombic loop pairs results in a single‐layer wide stopband FSS with linear reflection phase under normal incidence. Both polarization dependent merged DRL (MDRL) and independent BTB DRL FSSs are developed and experimentally validated. As per measurements, the BTB printed FSS array exhibits 4.3 GHz wide stopband with transmission nulls at 7.9 and 10 GHz while the single side printed FSS exhibits 3.7 GHz wide stopband with transmission null at 8.3 GHz.
Local convergence of alternating low‐rank optimization methods with overrelaxation
Authors: Oseledets Ivan V. , Rakhuba Maxim V. , Uschmajew André 
Published: July 2022

AbstractThe local convergence of alternating optimization methods with overrelaxation for low‐rank matrix and tensor problems is established. The analysis is based on the linearization of the method which takes the form of an SOR iteration for a positive semidefinite Hessian and can be studied in the corresponding quotient geometry of equivalent low‐rank representations. In the matrix case, the optimal relaxation parameter for accelerating the local convergence can be determined from the convergence rate of the standard method. This result relies on a version of Young's SOR theorem for positive semidefinite block systems.
Adaptive project management model for the international development and aid projects
Authors: Mahmoud Saleh Firas Izzat , Karia Noorliza 
Published: July 2022

AbstractThis paper develops an adaptive Project Management Model (PM‐Model) for the International Development and Aid Projects (IDAPs) that International Non‐Governmental Organizations (INGOs) implement by integrating IDAPs' requirements grounded in Total Quality Management (TQM) and Core Humanitarian Standards (CHS). The three‐round Delphi process allows experts' opinions to identify the deficiencies of the PMBOK® Guide to propose an adaptive PM‐Model for the management of IDAPs. Seven experts suggest the required adaptations in Round‐1 and narrow down the transformations in Round‐2. Then, in Round‐3, nine practitioners validate the proposed new model of the final adaptive PM‐Model that entails eight adaptions to the PMBOK® Guide for the interest of IDAPs and vulnerable people reached by these projects. The result contributes to the PM theory by providing an adaptive PM‐Model for the international development industry. This study addresses the practical problems faced by the practitioners. Thus, it promotes people's inclusion and decision‐making, relevancy of provided assistance by IDAPs, accountability, coordination, local capacities and community leadership, monitoring and evaluation, and satisfying donors of IDAPs.
Simple synthesis of cellulose hydrogels based on the direct dissolution of cellulose in tetrabutylphosphonium hydroxide followed by crosslinking
Authors: Nguyen Mai Ngoc , Tran Tuyet Thi , Nguyen Quynh Thi , Tran Thi Thuy , Nguyen Bang Cong , Hollmann Dirk 
Published: July 2022

AbstractCellulose‐based hydrogels are valuable sustainable materials with significant potential applications in biomedical fields such as cell therapy, hemostasis, wound healing, tissue transplantation, regeneration technology, and drug delivery carrier to cells. In contrast to previous studies, the standard synthesis procedure needs high temperature, low cellulose concentration, and many additives. Here cellulose‐based hydrogels with a high cellulose concentration are produced at room temperature. The one‐pot preparation of chemical hydrogels involves the dissolution of cellulose in tetrabutylphosphonium hydroxide followed by epichlorohydrin crosslinking. The effects of the wide range of microcrystalline cellulose concentrations and the crosslinker ratio on swelling properties and crosslink density under different conditions are investigated. The hydrogels are characterized using Fourier transform infrared spectroscopy and X‐ray diffraction. The morphology of hydrogels is examined through scanning electron microscope. The transparency of hydrogel is determined by ultraviolet–visible (UV–vis) spectrophotometer.
Enhancing the properties of graphene oxide/natural rubber nanocomposite‐based strain sensor modified by amino‐functionalized silanes
Authors: Woraphutthaporn Sarinya , Pattananuwat Prasit , Hayichelaeh Chesidi , Kobayashi Takaomi , Boonkerd Kanoktip 
Published: July 2022

AbstractThis work investigates the influence of modified graphene oxide (mGO) on the properties of natural rubber (NR) nanocomposites. GO was modified by amino‐functionalized silane coupling agents, that is, (3‐aminopropyl)triethoxysilane (APTES) and [3‐(2‐aminoethyl amino)propyl]trimethoxysilane (TMPES), hereafter referred to as AGO and TGO, respectively. The use of silane‐mGOs had a positive effect on the properties of the NR nanocomposites compared with unmodified GO, that is, a faster cure time, increased crosslink density, strengthened filler–rubber interaction, improved filler dispersion, and enhanced mechanical and electrical properties. Among the different types of silanes, the TGO/NR nanocomposite showed better mechanical and electrical properties than the AGO/NR nanocomposite because of its high crosslink density and strong filler–rubber interaction. To ascertain the potential for application as a strain sensor, the electrical resistance of nanocomposites during finger motion was determined. An increase in electrical resistance of the nanocomposites containing mGOs during finger motion was observed, which strongly supports the finding that NR nanocomposites containing silane‐mGOs are a potentially suitable material to produce a strain sensor.
Spent coffee grounds: An intriguing biowaste reinforcement of thermoplastic starch with potential application in green packaging
Authors: H. T. Nguyen Vy , M. N. Prabhakar , Lee Dong‐Woo , Song Jung‐il 
Published: July 2022

AbstractWith respect to the explosion of single‐use plastic packaging consumption during the COVID‐19 pandemic, environmentally friendly substitutes are critically needful for sustainable development. Therefore, the present work focuses on the functional properties of bioplastic blends prepared through hot compressing molding of thermoplastic starch (TPS) and spent coffee grounds (SCG) in different ratios (0%–20% SCG) as the potential features of SCG were extensively employed in biocomposites for the first time. The insertion of dark brown SCG into TPS hindered UV transmission by 100% at 320 nm and 99.2% at 400 nm. Moreover, the samples with 15% and 20% SCG induced a surge in radical scavenging activity from 7.95% to over 92% at a concentration of 0.1 g/ml owing to the rich source of antioxidants in SCG. The lignin component and high carbon content also improved the thermal performance of TPS/SCG blends, enhancing thermal stability, delaying onset and maximum degradation temperatures, and achieving the HB rating in the UL‐94 test. Compared to a pure TPS matrix, TPS blends incorporating up to 10% SCG exhibited improvement in elastic modulus without deterioration of tensile strength.
Transcriptome–proteome compendium of the Antarctic krill (Euphausia superba): Metabolic potential and repertoire of hydrolytic enzymes
Authors: Möller Lars , Vainshtein Yevhen , Wöhlbrand Lars , Dörries Marvin , Meyer Bettina , Sohn Kai , Rabus Ralf 
Published: July 2022

AbstractThe Antarctic krill (Euphausia superba Dana) is a keystone species in the Southern Ocean that uses an arsenal of hydrolases for biomacromolecule decomposition to effectively digest its omnivorous diet. The present study builds on a hybrid‐assembled transcriptome (13,671 ORFs) combined with comprehensive proteome profiling. The analysis of individual krill compartments allowed detection of significantly more different proteins compared to that of the entire animal (1464 vs. 294 proteins). The nearby krill sampling stations in the Bransfield Strait (Antarctic Peninsula) yielded rather uniform proteome datasets. Proteins related to energy production and lipid degradation were particularly abundant in the abdomen, agreeing with the high energy demand of muscle tissue. A total of 378 different biomacromolecule hydrolysing enzymes were detected, including 250 proteases, 99 CAZymes, 14 nucleases and 15 lipases. The large repertoire in proteases is in accord with the protein‐rich diet affiliated with E. superba’s omnivorous lifestyle and complex biology. The richness in chitin‐degrading enzymes allows not only digestion of zooplankton diet, but also the utilisation of the discharged exoskeleton after moulting.
The therapeutic effects of berberine against different diseases: A review on the involvement of the endoplasmic reticulum stress
Authors: Yarmohammadi Fatemeh , Hayes A. Wallace , Karimi Gholamreza 
Published: July 2022

AbstractVarious factors interfere with the endoplasmic reticulum (ER) function, which is involved in protein folding and calcium homeostasis. ER dysfunction referred to as ER stress triggers cell death by apoptosis and inflammation. Berberine (BBR) is an alkaloid extracted from the family Berberidacea. It has shown multiple pharmacological activities, including anti‐inflammatory, antioxidative, anti‐apoptotic, antiproliferative, and antihypertensive. It has been reported that BBR can decrease apoptosis and inflammation following different pathological conditions, which might be mediated by targeting ER stress pathways. In this manuscript, we reviewed the protective potential of BBR against several diseases, such as metabolic disorders, cancer, intestinal diseases, cardiovascular, liver, kidney, and central nervous system diseases, in both in vivo and in vitro studies.