bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface integrity of hybrid CM247LC/Inconel 718 components produced by laser-directed energy deposition
Authors: Mehmeti Aldi , Bidare Prveen , Imbrogno Stano , Wimpenny David , Essa Khamis , Dimov Stefan 
Published: July 2022

AbstractHigh-temperature alloys pose significant challenges in additive manufacturing. These materials have unique properties, such as high resistance to mechanical and chemical degradation when exposed to high temperatures. Furthermore, when these alloys are used to produce hybrid components with other similar alloys, investigating their surface integrity is critical because any residual stress can lead to early stage cracks and poor fatigue performance. In this research, a hybrid manufacturing approach is employed to produce components from difficult to weld alloys, i.e. CM247LC deposited on IN718 through a laser based direct energy deposition (L-DED) process. The surface integrity, mechanical properties and microstructure of such hybrid components is investigated, especially their welding/joint areas. Crack-free processing regimes were established to deposit CM247LC while mitigating the negative effects onto the microstructure of the Inconel substrate. Especially, the thermal gradients were managed to deliver crack free sections of CM247LC with good interface bonding, strength and fine microstructure. It is important to note that this is achieved without any significant preheating that contrasts with what is reported in other investigations so far. Furthermore, end-use hybrid blisks with deposited CM247LC blades onto Inconel 718 disks (HUB) were manufactured and then machined within a single processing set-up. The results show that the substrate thickness, the machining between the deposited layers and the final machining and heat-treatment play a role in reducing residual stresses. Ultimately, such hybrid manufacturing approach can be considered a new solution for producing such components and also for their subsequent repair.
Social status predicts different mating and reproductive success for men and women in China: evidence from the 2010–2017 CGSS data
Authors: Zhang Yikang , Santtila Pekka 
Published: July 2022

Abstract
Evolutionary psychological theories posit that higher social status is conducive to men’s reproductive success. Extant research from historical records, small scale societies, as well as industrialized societies, support this hypothesis. However, the relationship between status difference between spouses and reproductive success has been investigated less. Moreover, even fewer studies have directly compared the effect of status and status difference between spouses on reproductive success in men and women. Using data from the Chinese General Social Survey (CGSS) conducted between 2010 and 2017 (N = 55,875; 28,931 women) and operationalizing social status as standardized income and educational level (compared with same-sex peers), we examined how social status and relative status between spouses impact men’s and women’s mating and reproductive success. We found that (1) men with higher social status were more likely to have long-term mating (being in a marriage and/or not going through marriage disruption) and reproductive success, mainly through having a lower risk of childlessness; (2) women with higher social status were less likely to have mating and reproductive success; and (3) relative status between spouses had an impact on the couple’s reproductive success so that couples, where the husband had higher status compared to the wife, had higher reproductive success. Thus, social status positively impacted men’s reproductive success, but relative status between spouses also affected mating and impacted childbearing decisions.

Significance statement
In terms of standardized educational level and income among peers, social status positively predicts men’s mating and reproductive success in contemporary China. However, while a higher social status increases the probability of having at least one child, it does not predict a greater number of children for men. A status difference between spouses, on the other hand, consistently predicts having children. Thus, the higher the husband’s status relative to his wife, the greater the likelihood of having the first, second, and third children. The current results suggest that when examining the effect of status on mating and reproduction, social status and status within a family should be considered. We also stress the importance of exploring the potential proximate mechanisms by which a status difference influences childbearing decisions.
MRI changes in diaphragmatic motion and curvature in Pompe disease over time
Authors: Harlaar Laurike , Ciet Pierluigi , van Tulder Gijs , van Kooten Harmke A. , van der Beek Nadine A. M. E. , Brusse Esther , de Bruijne Marleen , Tiddens Harm A. W. M. , van der Ploeg Ans T. , van Doorn Pieter A. 
Published: July 2022

Abstract
Objectives
To evaluate changes in diaphragmatic function in Pompe disease using MRI over time, both during natural disease course and during treatment with enzyme replacement therapy (ERT).

Methods
In this prospective study, 30 adult Pompe patients and 10 healthy controls underwent pulmonary function tests and spirometry-controlled MRI twice, with an interval of 1 year. In the sagittal view of 3D gradient echo breath-hold acquisitions, diaphragmatic motion (cranial-caudal ratio between end-inspiration and end-expiration) and curvature (diaphragm height and area ratio) were calculated using a machine learning algorithm based on convolutional neural networks. Changes in outcomes after 1 year were compared between Pompe patients and healthy controls using the Mann-Whitney test.

Results
Pulmonary function outcomes and cranial-caudal ratio in Pompe patients did not change significantly over time compared to healthy controls. Diaphragm height ratio increased by 0.04 (−0.38 to 1.79) in Pompe patients compared to −0.02 (−0.18 to 0.25) in healthy controls (p = 0.02). An increased diaphragmatic curvature over time was observed in particular in untreated Pompe patients (p = 0.03), in those receiving ERT already for over 3 years (p = 0.03), and when severe diaphragmatic weakness was found on the initial MRI (p = 0.01); no progression was observed in Pompe patients who started ERT less than 3 years ago and in Pompe patients with mild diaphragmatic weakness on their initial MRI.

Conclusions
MRI enables to detect small changes in diaphragmatic curvature over 1-year time in Pompe patients. It also showed that once severe diaphragmatic weakness has occurred, improvement of diaphragmatic muscle function seems unlikely.

Key Points
• Changes in diaphragmatic curvature in Pompe patients over time assessed with 3D MRI may serve as an outcome measure to evaluate the effect of treatment on diaphragmatic function.
• Diaphragmatic curvature showed a significant deterioration after 1 year in Pompe patients compared to healthy controls, but the curvature seems to remain stable over this period in patients who were treated with enzyme replacement therapy for less than 3 years, possibly indicating a positive effect of ERT.
• Improvement of diaphragmatic curvature over time is rarely seen in Pompe patients once diaphragmatic motion shows severe impairment (cranial-caudal inspiratory/expiratory ratio < 1.4).
Effect of curcumin supplementation on exercise-induced muscle damage: a narrative review
Authors: Nanavati K. , Rutherfurd-Markwick K. , Lee S. J. , Bishop N. C. , Ali A. 
Published: July 2022

AbstractCurcumin, a natural polyphenol extracted from turmeric, is a potent antioxidant and anti-inflammatory agent. In the past few decades, curcumin’s ability to impact chronic inflammatory conditions such as metabolic syndrome, arthritis, and cancer has been widely researched, along with growing interest in understanding its role in exercise-induced muscle damage (EIMD). EIMD impacts individuals differently depending on the type (resistance exercise, high-intensity interval training, and running), intensity, and duration of the exercise. Exercise disrupts the muscles’ ultrastructure, raises inflammatory cytokine levels, and can cause swelling in the affected limb, a reduction in range of motion (ROM), and a reduction in muscular force-producing capacity. This review focuses on the metabolism, pharmacokinetics of various brands of curcumin supplements, and the effect of curcumin supplementation on EIMD regarding muscle soreness, activity of creatine kinase (CK), and production of inflammatory markers. Curcumin supplementation in the dose range of 90–5000 mg/day can decrease the subjective perception of muscle pain intensity, increase antioxidant capacity, and reduce CK activity, which reduces muscle damage when consumed close to exercise. Consumption of curcumin also improves muscle performance and has an anti-inflammatory effect, downregulating the production of pro-inflammatory cytokines, including TNF-α, IL-6, and IL-8. Curcumin may also improve oxidative capacity without hampering training adaptations in untrained and recreationally active individuals. The optimal curcumin dose to ameliorate EIMD is challenging to assess as its effect depends on the curcumin concentration in the supplement and its bioavailability.
Tape suture constructs for instabilities of the pubic symphysis: is the idea of motion preservation a suitable treatment option? A cadaver study
Authors: Cavalcanti Kußmaul Adrian , Schwaabe Fanny , Kistler Manuel , Jörgens Maximilian , Schreyer Korbinian F. , Greiner Axel , Böcker Wolfgang , Becker Christopher A. 
Published: July 2022

Abstract
Introduction
Current gold standard for the treatment of symphyseal disruptions includes anterior plating, almost entirely prohibiting symphyseal mobility and resulting in an iatrogenic arthrodesis followed by high rates of implant failure. Minimally invasive tape suture constructs have been found to maintain the micro mobility of ligamentous injuries, yet still providing sufficient biomechanical stability. Recently, this technique has been primarily investigated for symphyseal disruptions on synthetic pelvic models. Therefore, the aim of this study was to examine the feasibility of this novel flexible osteosynthesis on cadaveric pelvic models based on the following hypothesis: tape suture constructs ensure sufficient biomechanical stability without inhibiting micro mobility of the pubic symphysis for the treatment of symphyseal disruptions and maintain stability during long-term loading.

Materials and methods
9 cadaveric anterior pelvic rings were used in this study and a symphyseal disruption was created in every specimen. The specimens were then exposed to short- and long-term vertical and horizontal cyclic loading after treatment with a tape suture construct in criss-cross technique. The mean maximum displacement (mm) during cyclic loading and the corresponding stiffness (N/mm) were measured and compared.

Results
Regarding both displacement (mm) and corresponding stiffness (N/mm), the tape sutures displayed a significant difference between short- and long-term loading for cranial and caudal vertical loading (p < 0.01) but differences remained non-significant for horizontal loading (p > 0.05). No tape suture suffered from implant failure during long-term loading.

Conclusions
The tape suture construct displayed sufficient biomechanical stability without exceeding the physiological mobility of 2 mm of the pubic symphysis; however, also maintained the desired micro mobility of the affected joint necessary to prevent an iatrogenic arthrodesis. Further, all tape sutures maintained stability throughout long-term loading.
Twinkle artifact in sonographic breast clip visualization
Authors: Maggie Banys-Paluchowski , Peter Paluchowski , Natalia Krawczyk 
Published: July 2022

AbstractThe ‘twinkle’ or ‘twinkling’ artifact represents a phenomenon observed using color Doppler ultrasound that leads to a rapid alternation of color in and immediately behind an echogenic and highly reflective object. It occurs during sonographic examination of kidney stones, and has been also described in clips used for marking breast and axillary lesions.
The heritability of vocal tract structures estimated from structural MRI in a large cohort of Dutch twins
Authors: Dediu Dan , Jennings Emily M. , van’t Ent Dennis , Moisik Scott R. , Di Pisa Grazia , Schulze Janna , de Geus Eco J. C. , den Braber Anouk , Dolan Conor V. , Boomsma Dorret I. 
Published: July 2022

AbstractWhile language is expressed in multiple modalities, including sign, writing, or whistles, speech is arguably the most common. The human vocal tract is capable of producing the bewildering diversity of the 7000 or so currently spoken languages, but relatively little is known about its genetic bases, especially in what concerns normal variation. Here, we capitalize on five cohorts totaling 632 Dutch twins with structural magnetic resonance imaging (MRI) data. Two raters placed clearly defined (semi)landmarks on each MRI scan, from which we derived 146 measures capturing the dimensions and shape of various vocal tract structures, but also aspects of the head and face. We used Genetic Covariance Structure Modeling to estimate the additive genetic, common environmental or non-additive genetic, and unique environmental components, while controlling for various confounds and for any systematic differences between the two raters. We found high heritability, h2, for aspects of the skull and face, the mandible, the anteroposterior (horizontal) dimension of the vocal tract, and the position of the hyoid bone. These findings extend the existing literature, and open new perspectives for understanding the complex interplay between genetics, environment, and culture that shape our vocal tracts, and which may help explain cross-linguistic differences in phonetics and phonology.
Soil substrate culturing approaches recover diverse members of Actinomycetota from desert soils of Herring Island, East Antarctica
Authors: Benaud Nicole , Chelliah Devan S. , Wong Sin Yin , Ferrari Belinda C. 
Published: July 2022

AbstractAntimicrobial resistance is an escalating health crisis requiring urgent action. Most antimicrobials are natural products (NPs) sourced fromActinomycetota, particularly theStreptomyces. Underexplored and extreme environments are predicted to harbour novel microorganisms with the capacity to synthesise unique metabolites. Herring Island is a barren and rocky cold desert in East Antarctica, remote from anthropogenic impact. We aimed to recover rare and cold-adapted NP-producing bacteria, by employing two culturing methods which mimic the natural environment: direct soil culturing and the soil substrate membrane system. First, we analysed 16S rRNA gene amplicon sequencing data from 18 Herring Island soils and selected the soil sample with the highestActinomycetotarelative abundance (78%) for culturing experiments. We isolated 166 strains across three phyla, including novel and rare strains, with 94% of strains belonging to theActinomycetota. These strains encompassed thirty-five ‘species’ groups, 18 of which were composed ofStreptomycesstrains. We screened representative strains for genes which encode polyketide synthases and non-ribosomal peptide synthetases, indicating that 69% have the capacity to synthesise polyketide and non-ribosomal peptide NPs. FourteenStreptomycesstrains displayed antimicrobial activity against selected bacterial and yeast pathogens using an in situ assay. Our results confirm that the cold-adapted bacteria of the harsh East Antarctic deserts are worthy targets in the search for bioactive compounds.
Pineal cysts without hydrocephalus: microsurgical resection via an infratentorial-supracerebellar approach—surgical strategies, complications, and their avoidance
Authors: Fleck Steffen , Damaty Ahmed El , Lange Ina , Matthes Marc , Rafaee Ehab El , Marx Sascha , Baldauf Jörg , Schroeder Henry W. S. 
Published: July 2022

Abstract
Indications for surgery of pineal cysts without ventriculomegaly are still under debate. In view of the limited data for pineal cyst resection in the absence of hydrocephalus, and the potential risk of this approach, we have analyzed our patient cohort focusing on strategies to avoid complications according to our experience in a series of 73 pineal cyst patients. From 2003 to 2015, we reviewed our database retrospectively for all patients operated on a pineal cyst. Furthermore, we prospectively collected patients from 2016 to 2020. In summary, 73 patients with a pineal cyst were treated surgically between 2003 and 2020. All patients were operated on via a microscopic supracerebellar-infratentorial (SCIT) approach. The mean follow-up period was 26.6 months (range: 6–139 months). Seventy-three patients underwent surgery for a pineal cyst. An absence of enlarged ventricles was documented in 62 patients (51 female, 11 male, mean age 28.1 (range 4–59) years). Main presenting symptoms included headache, visual disturbances, dizziness/vertigo, nausea/emesis, and sleep disturbances. Complete cyst resection was achieved in 59/62 patients. Fifty-five of 62 (89%) patients improved after surgery with good or even excellent results according to the Chicago Chiari Outcome Scale, with complete or partial resolution of the leading symptoms. Pineal cysts resection might be an indication in certain patients for surgery even in the absence of ventriculomegaly. The high percentage of postoperative resolution of quality-of-life impairing symptoms in our series seems to justify surgery. Preoperatively, other causes of the leading symptoms have to be excluded.
Heavy metals removal/stabilization from municipal solid waste incineration fly ash: a review and recent trends
Authors: Ajorloo Mojtaba , Ghodrat Maryam , Scott Jason , Strezov Vladimir 
Published: July 2022

AbstractWaste treatment using thermal technologies, such as incineration, leads to the production of pollutants and wastes, including fly ash (FA). Fly ash contains heavy metals (HMs) and other contaminants and can potentially pose high risks to the environment and negatively impact health and safety. Consequently, stabilizing fly ash prior to either use or landfilling is crucial. The toxicity of fly ash through heavy metal leaching can be assessed using leaching tests. The leaching rates of heavy metals primarily depend on the surrounding conditions as well as fly ash properties and metal speciation. Physical separation, leaching or extraction, thermal treatment and solidification/chemical stabilization are proposed as suitable approaches for fly ash treatment. Economic considerations, environmental concerns, energy consumption and processing times can define the efficiency and selection of the treatment approach. This review considers the latest findings and compares the advantages and shortcomings of different fly ash treatment methods with the aim of highlighting the recent advances in the field. The review concludes that the simultaneous implementation of various methods can lead to highly efficient heavy metals removal/stabilization while simultaneously taking economic and environmental considerations into account.
Fostering Social Impact Through Corporate Implementation of the SDGs: Transformative Mechanisms Towards Interconnectedness and Inclusiveness
Authors: Fiandrino Simona , Scarpa Francesco , Torelli Riccardo 
Published: July 2022

AbstractThe United Nations (UN) 2030 Agenda for Sustainable Development has considerable potential for achieving a more sustainable future. However, the concrete realisation of Sustainable Development Goals (SDGs) is impeded by how they are implemented by a diverse set of competent agents. This conceptual paper draws on social impact theory to investigate how businesses can utilise the SDG framework to achieve positive social outcomes. We identify two pathways that can guide businesses to improve their SDGs interventions, which entail considering the interconnections between the goals that are directly or indirectly affected by the initiative at stake and the inclusiveness of the actors affected by the SDGs. Building on the literature on hybrid organising (to frame interconnectedness) and the literature on multi-stakeholder partnerships and deliberative governance (to frame inclusiveness), we discuss a set of organisational mechanisms and transformations that can help businesses ensure that their SDGs interventions are more socially impactful. By doing so, this paper extends the literature on the role of companies for sustainable development and provides some practical implications.
A Decision Theory Perspective on Wicked Problems, SDGs and Stakeholders: The Case of Deforestation
Authors: Alexander Anthony , Walker Helen , Delabre Izabela 
Published: July 2022

AbstractThe Sustainable Development Goals (SDGs) are an opportunity to address major social and environmental challenges. As a widely agreed framework they offer a potential way to mobilise stakeholders on a global scale. The manner in which the goals, with time-based targets and specific metrics, are set out within a voluntary reporting process adopted by both governments and business, provides a fascinating and important case for organisational studies. It is both about advancing performance measurement and evidence-based policy-making for sustainable development, and also participation and consultation at a wider, more global scale, than has ever been possible before. This paper contributes to the notion of SDGs as a wicked problem, answering calls for deeper theorisation, via synthesis with core ideas in the management field of decision theory. A case study on the wicked problem of deforestation and its links to supply chains, multi-stakeholder initiatives and SDG reporting, provides an illustration of the relevance of the application of decision theory to wicked problems, presented using a novel conceptual framework. This helps to illustrate new avenues for research and practical application regarding the balance of technocratic and participative approaches for sustainable development.
Penalized Averaging of Quantile Forecasts from GARCH Models with Many Exogenous Predictors
Authors: Gooijer Jan G. De 
Published: July 2022

AbstractThis study explores the multi-step ahead forecasting performance of a so-called hybrid conditional quantile method, which combines relevant conditional quantile forecasts from parametric and semiparametric methods. The focus is on lower (left) and upper (right) tail quantiles of the conditional distribution of the response variable. First, we evaluate and compare out-of-sample conditional quantile forecasts obtained from a hybrid method and from five non-hybrid methods, employing a large data set of exogenous predictors generated by various GARCH model specifications. Second, we compare the accuracy of these methods by calculating conditional quantile forecasts for the risk premium of the monthly S&P 500 index, using a data set of macroeconomic predictors. Monte Carlo and empirical application results indicate that the hybrid forecasting provides more accurate quantile forecasts than non-hybrid methods. The success of the hybrid method is most prominent when compared with results obtained by a simple equal-weighted combination of quantile forecasts.