bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of serum high sensitivity C - reactive protein, adipokines, HbA1c, and fasting blood glucose level in patients of diabetes mellitus type II with periodontal disease
Authors: Lahariya Shiv Narayan , Sarkar Purnima Dey , Verma Vandana , Bhatt Ajay 
Published: August 2022

: Diabetes is a systemic disease with several complications affecting both the length and quality of life. One of these complications is periodontal disease (periodontitis). The periodontal diseases are considered as the “sixth complication of diabetes mellitus”. The results of this study indicate the presence of a significant relationship between periodontitis and diabetes mellitus. A total of 155 periodontitis patients with diabetes mellitus and 137 periodontitis patients without diabetes mellitus were selected for the study. Hs-CRP (High sensitivity C – Reactive Protein), Adipokines, HbA1c, and Fasting Blood sugar levels were compared with 160 healthy non-diabetics; non-periodontitis (control) subjects.FBS (Fasting Blood sugar) & HbA1c were done by semi auto-analyzer diagnostic kit and Adipokines by ELISA method (Kit method) and Hs-CRP (High sensitivity C - Reactive Protein) was estimated by Immunoturbidimetric method. For this study newly diagnosed type 2 diabetic and periodontitis patients were selected. : FBS and HbA1c in both study groups were higher than that in control group. Statistical analysis showed that periodontitis with at least one tooth that displayed a probing pocket depth of &#62; or = 6mm was significantly associated with higher blood sugar (P=0.005) and positive correlations are found between mean periodontal disease and HbA1c (P = 0.009). Adipokines, HbA1c, Hs-CRP (High sensitivity C - Reactive Protein), and periodontal parameters have significant role in periodontitis with diabetes mellitus. The link between periodontal disease and type 2 Diabetes mellitus (T2DM) has been suggested through a number of clinical and epidemiological studies. Many studies have shown that the prevalence and severity of periodontitis is increased in the presence of diabetes mellitus. Thus, diabetes is considered to be a risk factor for gingivitis and periodontitis.
Spirometric surveillance of obstructive lung diseases
Authors: Peter Lavanya S 
Published: August 2022

Obstructive Lung Disease (OLD) becomes global health issues that influencing the physical health and economic conditions of people. Chronic Respiratory Disease (CRD) is the disease of airways characterized by obstruction and influencing the structure of the lungs. It includes chronic bronchitis, COPD, emphysema and asthma. The most common disease is Chronic Obstructive Pulmonary Disease (COPD). The major causes of COPD involve exposure to an irritant that damage the lungs and airways that can cause such disease.1):Assess the prevalence of OLD among the patients admitted to general medical wards using spirometry; 2): Use a symptom questionnaire for screening patients with OLD and compare it with Spirometry; 3): Association of various medical co-morbidities with the diagnosis of OLD.The screening for OLDs and factors that are influencing it along with co morbidities were analyzed. This is a descriptive study conducted on patients admitted to general medical wards in hospital of South India for a period of 2 years. The study has involved the patients who are admitted in general wards and aged &#62; 40 years.The physician diagnosis of OLD at admission was in 21 out of 144 patients. It was by symptom alone in 11% (16 of 144 patients) and based on spirometry in 3.48% (5 of 144) only. During the hospitalization the diagnosis of OLD increased by 2.08% (3 of 144) on the basis of symptom alone and 1.4% (2 of 144) by spirometry, cumulatively by 3.48% (5 of 144). Therefore, at admission about 14.48% were diagnosed to have OLD. An ROC curve was plotted and the area under the curve was 0.77 95% CI (0.688 — 0.865). By ROC coordinates a cut off of 15.5 for detecting OLDs showed a sensitivity and specificity of 71% and 78% respectively with a positive predictive value of 56% and negative predictive value of 87%.With the additional yield of Spirometry and association of medical comorbidities can help identify the conditions of patients earlier and pave way for offering appropriate holistic treatment.
Postoperative pulmonary complications following head and neck oncosurgery - Case control study
Authors: Nallusamy Selvaraj , Surya P Sakthi , G Balamurugan 
Published: August 2022

Head and neck cancers (HNC) constitute about one-third of all cancers in India. A combination of surgery, chemotherapy and radiotherapy is used to manage them. There is a high incidence of PPCs following head and neck surgeries. The probable mechanisms behind it are alteration in swallowing mechanisms and impairment in protective factors of the laryngeal apparatus.To study the association between the clinicodemographic and perioperative parameters and the occurrence of PPCs following head and neck oncosurgery. This case-control study was conducted in150 patients after head and neck oncosurgery. 50 patients as cases with complications and 100 patients as control with no complications were included in the study after getting informed consent and results were statistically analyzed and discussed. A pre-tested semi-structured case study form was used to collect patient information. Mean ages among cases and controls were 58.76 ± 10.40 and 56.10 ± 12.61. Weight loss was present in 26% of patients and 8% of controls. Malignancy of the tongue was the most common among both patients and controls, constituting 22% and 25%, respectively, followed by mouth and larynx. Preoperative albumin levels, presence of ARI within one month of surgery and lack of preoperative pulmonary rehabilitation had a significant association with the development of PPCs.From this study, we concluded correction of the modifiable preoperative risk factors might prove beneficial in reducing the incidence of PPCs.
Evaluation of interleukin-6 and C - reactive protein as a inflammatory mediators in type 2 diabetic subjects in Indian population of Bhopal
Authors: Dubey Akanksha , Hisalkar Prashant J , Patne Anupama 
Published: August 2022

India leads the world with the largest number of Diabetic subjects, hence can be called as Diabetic Capital of World. Type 2 Diabetes Mellitus (T2DM) is a metabolic disorder resulting from insulin insufficiency or function. The researches in past decade have revealed a critical link between metabolic disorders and inflammation which leads to a concept called metaflammation. The linkage of inflammation and type 2 diabetes mellitus (T2DM) has been extensively investigated for over a decade. The main objective of the study is to assess inflammatory markers in T2DM subjects by measuring cytokines and acute phase proteins and its comparison with healthy controls. Total 100 subjects were studied which were divided into two groups of 100 of Diabetic cases and 100 Healthy controls after defining proper inclusion and exclusion criteria. Gender wise distribution was also done. FPG, 2H-PG, HbA1C and CRP were estimated on fully automated analyzers while IL-6 was estimated by ELISA. The result had shown that cases have significantly elevated IL-6 and CRP when compared to age and sex matched healthy controls with p&#60;0.0001. FPG, 2H-PG and HbA1c was also significantly elevated in cases as compared to healthy subjects. We had also compared inflammatory and glycemic markers on the basis of gender. We can conclude that in developing countries like India estimation of inflammatory markers along with glycemic markers can predict secondary complications of disease.
Medical student’s attitude towards serving rural areas: A cross sectional study in Maharashtra, India
Authors: Sahu Priyanka Chintaram , I F Inamdar , Sahu Ajaykumar Chintaram 
Published: August 2022

Rural population of India is grossly underserved by healthcare professionals. Gap exits between health services for urban and rural communities. 1) To determine the attitude of medical students towards serving rural areas and factors affecting it. 2) To explore reasons behind willingness and unwillingness to work in rural areas.It was a cross-sectional study conducted in medical colleges. Among three medical colleges in city, two medical colleges were selected by simple random sampling using lottery method. All 450 undergraduate medical students in both selected medical colleges were included into the study. Binary logistic regression analysisOdds ratio,Chi-square test and percentages were used to analyse the data.35.82% medical students were interested in working at rural areas. Age, parental education, place of residence, type of college and year of undergraduation of medical students had significant association with their preference towards rural practice. Social service was commonest reason students being interested in working rural area while scarcity of health facilities was major cause for negative attitude towards rural practice. Majority of medical students were not in favour of working in rural areas. Urban rural disparity was more obvious among Allopathy students. There is need to focus on working environment at rural areas as lack of amenities in the rural areas was a common reason behind unwillingness of students towards rural practice.
Role of diagnostic laparoscopy in chronic pelvic pain in females: A study from tertiary care centre in Patna, Bihar
Authors: Singh Kalpana , Pankaj Deepak , Kumar Nitesh , Muni Sweta , Bhushan Vibhuti , Kumar Bipin , Nirupam  , Kumar Santosh 
Published: August 2022

Chronic pelvic pain in females is one of the most bemusing problems that are faced by doctors in day to day practice as physical signs are nonspecific. Laparoscopy is one of the worthy tools in cases of chronic pelvic pain as not only it establishes the diagnosis but often treatment can be instituted in the same sitting. The present study aimed to evaluate whether diagnostic value of laparoscopy is worth in cases with chronic pelvic pain in females.This study was done in the department of General Surgery and Reproductive Medicine at Indira Gandhi Institute of Medical sciences, Patna, Bihar from July 2019 to March 2021. Seventy five female patients were included in this study. The analysis and interpretation of the data were performed using Microsoft excel. The quantitative data obtained were expressed as percentage in tabular form.: The studied patients were in the age group ranging from 15 – 65 years. Most patients 40 % (n=30) complaint of pain in right lower quadrant of abdomen. The most common finding during diagnostic laparoscopy was found to be tubercular pathology (22.67%) followed by pelvic adhesions (18.67%). Other diagnoses were pelvic inflammatory disease, endometriosis, cysts etc.Diagnostic Laparoscopy is a safe and effective tool to establish the aetiology of chronic pelvic pain and allows for appropriate interventions. It can serve as a time saving and cost effective implement for these patients with uncertain diagnosis.
Відбір джерел з неправдивою інформацію методом бджолиної колонії
Authors: Наконечний Володимир , Лаптєв Олександр , Погасій Сергій , Лазаренко Сергій , Мартинюк Ганна 
Published: August 2022

Основною метою еволюційної оптимізації є пошук такого поєднання параметрів (незалежних змінних), яке б сприяло максимізації або мінімізації якісних, кількісних та ймовірнісних характеристик розв’язуваної задачі. Останнім часом стала вельми поширеною отримали інтегровані методи оптимізації, які запозичують основні засади своєї роботи із живої природи. Дослідники експериментують з різними типами уявлень, так, еволюційні та генетичні алгоритми використовують методи селекції та генетичні оператори, відомо велике число алгоритмів заснованих на методі рою частинок.
Штучна бджолина колонія — це метод оптимізації, що імітує поведінку бджіл, специфічне застосування кластерного інтелекту, головна особливість якого полягає в тому, що йому не потрібно розуміти спеціальну інформацію про проблему, потрібно лише оптимізувати проблему. Порівняння неповноцінності за допомогою локальної оптимізаційної поведінки кожної людини зі штучною бджолою, нарешті, призводить до появи у групі глобального оптимального значення з вищою швидкістю збіжності.
У статті розглядається метод розв’язання задачі оптимізації, на основі моделювання поведінки бджолиної колонії. Опис моделі поведінки агентів розвідників та агентів фуражиров, механізми пошуку та вибір позицій у заданій околиці. Наведено загальну структуру оптимізаційного процесу. Також наведені графічні результати, які доводять можливість методу бджолиної колонії оптимізувати результати, тобто зі всій множені джерел інформації, метод бджолиної колонії шляхом оптимізації може значно обмежувати кількість джерел інформації, виявляти вузьке коло джерел у яких може бути неправдива інформація. Що у подальшому дозволить з більшою достовірністю розпізнавати саме джерела з неправдивою інформацією та заблокувати їх.
Методика визначення статичних характеристик ефективності діагностування телекомунікаційних та радіоелектронних систем
Authors: Соломенцев Олександр , Заліський Максим , Щербина Ольга , Яшанов Іван 
Published: August 2022

Стаття присвячена питанням обґрунтування доцільності застосування статистичних характеристик для показника ефективності процесу діагностування телекомунікаційних та радіоелектронних систем. Відомо, що використання телекомунікаційних та радіоелектронних систем за призначенням у промисловій діяльності з кожним роком має тенденцію до швидкого зростання. Тому неминучою вимогою до цих систем є підвищення рівня показників надійності та ремонтопридатності. Забезпечення надійності та ремонтопридатності телекомунікаційних та радіоелектронних систем є одним із основних завдань системи експлуатації. Система експлуатації містить у своєму складі обладнання, персонал, документацію, ресурси, засоби експлуатації, контрольно-вимірювальну апаратуру. У системі експлуатації реалізуються процеси використання за призначенням, технічного обслуговування, поточного ремонту, продовження ресурсу. Досвід експлуатації показує, що поточний ремонт складається з процедур діагностування, відновлення працездатності та моніторингу параметрів. Аналіз літератури у сфері діагностування телекомунікаційних та радіоелектронних систем показує, що проблемі визначення статистичних характеристик показників ефективності діагностування приділяється недостатньо уваги. При цьому більшість наукових результатів пов’язані з використанням тільки матема­тичних сподівань показників ефективності. Однак показник ефективності є стохастичним процесом, оскільки виникнення відмов носить випадковий характер. Такий процес можна охарактеризувати щільністю розподілу ймовірності, яка містить повну інформації про нього. Використання щільності розподілу ймовірності може дати можливість розробити більш точні алгоритми оброблення даних у системах експлуатації телекомунікаційних та радіоелектронних систем. В якості показника ефективності процесу діагностування обрано ймовірність правильного діагностування, оскільки в процесі діагностування можливі помилки першого та другого роду. Для цього показника розроблено покрокову методику визначення його статистичних характеристик. Унаслідок її реалізації може бути отриманий дискретний ряд розподілу для ймовірності правильного діагностування. Методика пояснюється на конкретному прикладі. При цьому як об’єкт діагностування обрано антенну систему для радіомоніторингу. Для неї побудовано діагностичну модель та два варіанти програм діагностування на основі інженерного методу та методу інформаційного параметру. У результаті розраховані два дискретні ряди розподілу для ймовірності правильного діагностування. Порівняльний аналіз також був доповнений розрахунком математичних сподівань ймовірності правильного діагностування та дисперсій для різних початкових даних. Результати дослідження можуть бути використані в процесі проєктування та вдосконалення системи експлуатації телекомунікаційних та радіоелектронних систем під час процесів діагностування.
INVESTIGATION OF THE EFFECTS OF LEARNING CENTERS ON THE DEVELOPMENT OF PRESCHOOLERS FROM PRESERVICE TEACHERS’ VIEWS
Authors: Kabadayi Abdülkadir 
Published: August 2022

In our country, due to the rapid increase in the rate of pre-school enrollment in recent years, the importance of the physical equipment of the schools has increased rapidly in order for these schools to provide quality education to their students. For this reason, the importance of learning centers that affect all developmental areas of the child has increased remarkably. In this study, it is aimed to examine the importance of learning centers in the preschool period and the level of their place in the education program in line with the opinions of teacher candidates. 20 pre-school teacher candidates participated in this research, which was organized in a qualitative design. These participants were asked 17 open-ended questions about learning centers. Necessary suggestions were made at the end of the research.
ACCOUNTING TERMINOLOGY AS AN IMPORTANT COMPONENT OF IMPROVING THE PROFESSIONAL KNOWLEDGE
Authors: Alver Jaan , Alver Lehte 
Published: August 2022

The aim of this paper is to explore the comparability and understanding of accounting terms in two languages – Russian and English. The paper deals with the content and accuracy of the Russian equivalents of English accounting terms based on English-Russian-English professional dictionaries. By analysing the translations of in bilingual dictionaries the difficulty in translating and understanding accounting terms correctly, and the danger of miscommunication, is highlighted.
THE EFFECT OF FAIRY TALES IN THE PRESCHOOL PERIOD: EVALUATION IN THE CONTEXT OF LANGUAGE DEVELOPMENT
Authors: Tatlılıoğlu Kasım , Senchylo-Tatlılıoğlu Nadiia 
Published: August 2022

A book is a tool an important and effective stimulant the development of the preschool children. The most effective books are the fairy tales which are very important for the preschool education children. The fairy tale has an important place in the child’s life. It has been frequently emphasized that fairy tales would be beneficial in many ways in terms of child development. Fairy tales also support children's language development. For this reason it is necessary to be very careful while teaching children language and giving language awareness. In this study is discussed the effect of fairy tales in the context of language development. For this purpose has been made a literature review.
МОДЕРНІЗАЦІЯ ТА ПЕРСПЕКТИВИ РОЗВИТКУ СИСТЕМИ ОСВІТИ В СУЧАСНОМУ СУСПІЛЬСТВІ
Authors: Гурська Людмила Борисівна 
Published: August 2022

Епоху нашого часу можна називати епохою змін, інновацій, інтелекту, глобалізації, яка вимагає оволодіти ключовими поняттями в інтелектуальній, громадянській, комунікаційній, інформаційній та освітній сферах, формує багатофункціональні засоби розвитку та модернізації в сучасному суспільстві.
ПЕДАГОГІЧНА МАЙСТЕРНІСТЬ ЯК ГОЛОВНА СКЛАДОВА ПЕДАГОГІЧНОЇ ДІЇ
Authors: Островська Людмила 
Published: August 2022

Стаття присвячена аналізу педагогічної майстерності як головна складова педагогічної дії; вчитель - основна дійова особа у реформуванні сучасної освіти. Проаналізовано стан державного управління неперервною освітою педагогічних працівників в Україні, зазначені проблеми реалізації неперервної освіти в українському освітньому просторі.
MiR-135a is highly expressed and aggravates inflammatory response in sepsis by targeting MYOM1
Authors: Chen Sheng , Zhang Han , Li Haoming 
Published: August 2022

Background: Our research attempted to explore the effect of miR-135a on lipopolysaccharide (LPS)-induced THP-1cells damage and its potential mechanism. Methods: LPS (1 μg/mL) was selected to mimic the injury of sepsis in vitro. qRT-PCR was used to detect miR-135a expression. The association between miR-135a and Myomesin 1 (MYOM1) was speculated bythe predication website and confirmed by the dual-luciferase assay. MYOM1 expression was observed by qRT-PCR and western blotting assays. The biological properties of THP-1cells were analyzed by cell counting kit-8 and flow cytometry assays. The concentration of TNF-α, IL-6 and IL-8 in cell supernatant was calculated by enzyme-linked immunosorbent assay. Results: A marked augmentation of miR-135a was observed in LPS-induced THP-1 cells. Moreover, depletion of miR-135a alleviated the LPS-induced THP-1 cells injury from the perspective of improving cell viability and reducing cell apoptosis. Importantly, MYOM1, which was under expressed in LPS-induced THP-1 cells, was identified as a target of miR-135a and negatively regulated by miR-135a. Additionally, the mitigative impact of miR-135a inhibitor on THP-1cells damage triggered by LPS was suppressed by MYOM1 depletion. Conclusions: Our study suggested that the protective effect of miR-135a inhibitor on LPS-induced THP-1 cells injury was realized by regulation of MYOM1, which might afford a pair of novel molecules for sepsis clinical diagnosis.
In dogs undergoing extrahepatic portosystemic shunt attenuation, does pretreatment with levetiracetam reduce postoperative seizure incidence?
Authors: Hawes Connor , Lazzerini Kali 
Published: August 2022

PICO question
PICO

Clinical bottom line
Category of research question
Treatment
The number and type of study designs reviewed
Four papers were critically reviewed. All were retrospective cohort studies
Strength of evidence
Moderate
Outcomes reported
In one paper levetiracetam was found to reduce the risk of post-attenuation seizures. In the remaining three papers no difference was found between the frequency of post-attenuation seizures and the use of levetiracetam
Conclusion
That prophylactic levetiracetam is not indicated for the use of preventing post-attenuation seizures in dogs surgically treated for extrahepatic portosystemic shunts

How to apply this evidence in practice
The application of evidence into practice should take into account multiple factors, not limited to: individual clinical expertise, patient’s circumstances and owners’ values, country, location or clinic where you work, the individual case in front of you, the availability of therapies and resources.
Knowledge Summaries are a resource to help reinforce or inform decision making. They do not override the responsibility or judgement of the practitioner to do what is best for the animal in their care.
Effect of Water Saturation on Gas-Accessible Effective Pore Space in Gas Shales
Authors: Chen Lei , Liu Keyu , Xu Liangwei , Jiang Shu , Fu Yonghong , Tan Jingqiang , Fan Yuchen 
Published: August 2022

Abstract
The existence and content of water will certainly affect the effective pore space of shales and therefore is a key point for the evaluation of in-situ gas content and gas flow capacity of shale reservoirs. In order to reasonably evaluate the gas storage and flow capacities of water-bearing shale reservoirs, the effect of water on the effective pore space of shales needs to be understood. In this study, the Upper Permian Longtan shale in the southeastern Sichuan Basin, China, was selected as an example to conduct nuclear magnetic resonance cryoporometry (NMRC) measurements under different water saturation levels. The gas-accessible effective pore spaces in shales under different water saturation levels were quantified, and the effect of water saturation on gas-accessible effective pore space in shales was investigated. The results show that water plays an important role in the gas-accessible effective pore space of shales. When the Longtan shale increases from a dry state to a water saturation of 65%, 75%, and 90%, the gas-accessible effective pore volume decreases by 35%-60% (average 46.3%), 50%-70% (average 58.8%), and 65%-82% (average 75.8%), respectively. Water has an effect on the gas-accessible effective pore space regardless of pore size, and the effect is the strongest in the 4-100 nm range, which may be mainly due to the high content of clay minerals in the Longtan shale. Our studies are of important theoretical significance and application prospects for accurately evaluating the gas-accessible effective pore space of gas shales under actual geological conditions.