bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adaptación de los Proyectos de Extensión Universitaria y Vinculación Social a tiempos de pandemia
Authors: Eguigure Yenny , Zepeda Rodríguez Onis Jessica 
Published: March 2022

La Pandemia por el COVID-19 obligó a las Instituciones de Educación Superior a redefinir sus estrategias para atender la comunidad universitaria en la nueva normalidad. La Universidad Pedagógica Nacional Francisco Morazán (UPNFM), como institución de educación superior responsable de la formación de los profesionales docentes del sistema educativo hondureño, ante la situación de crisis ocasionada por la Pandemia, desarrolló y presentó a la comunidad universitaria y la sociedad, su Protocolo y el conjunto de lineamientos para desarrollar las actividades relativas a la función sustantiva de extensión universitaria y vinculación social en la nueva normalidad.
El proceso para la construcción de estos instrumentos para el trabajo en extensión universitaria se desarrolló a partir de una lectura del contexto y la identificación de áreas o temas prioritarios para ser abordados desde un nuevo planteamiento que favoreciera la participación de la comunidad universitaria en las actividades en territorio.
Tomando como referente, el reconocimiento de la necesidad de articular la extensión universitaria con la comunidad tanto rural como urbana, se procedió a realizar un diagnóstico y caracterización de los problemas locales y nacionales que podrán atenderse desde los Proyectos de Extensión Universitaria y Vinculación Social (PREUVS).
La puesta en acto de los lineamientos definido se orienta hacia el establecimiento de estrategias para asegurar la modificación de las acciones planificadas partiendo de la situación de crisis por la emergencia marcada por el distanciamiento social y el confinamiento. El nuevo escenario demanda de la UPNFM la necesidad de buscar, identificar, proponer y desarrollar alternativas de solución a las problemáticas socioeducativas. Partiendo desde la naturaleza misma de la Universidad la reformulación de los PREUVS se visualiza como una acción concreta para dar una respuesta social desde la Universidad a las nuevas demandas de la comunidad.
Menimbang Gagasan Islamisasi Ilmu-ilmu Sosial; Studi Kritis atas Pemikiran Ismail Raji Al-Faruqi
Authors: Muhyidin Muhyidin , Mutmainnah Dewi 
Published: March 2022

The idea of Islamization of knowledge in essence emerged as a response to the dichotomy between religious science and science that the secular West and modern culture introduced into the Islamic world. The progress achieved by modern science has had an amazing effect, but on the other hand it has also had a negative impact, because modern (Western) science has dry values or is separated from religious values. In addition, the Islamization of Science is also a reaction to the crisis in the education system faced by Muslims, namely the dualism of the Islamic education system and modern (secular) education which confuses Muslims. According to Al-Faruqi, Islamization is an effort to understand and rebuild social and natural sciences in which there are Islamic elements, so that they change to be in line with Islamic orientation. And every scientific discipline must cultivate Islamic principles whose methodology is imbued with the spirit of monotheism, which includes: the principle of the oneness of God, the unity of the universe, the unity of truth and knowledge, the unity of life, and the unity of mankind
Upaya Peningkatan Pengetahuan Masyarakat dalam Pencegahan dan Penanggulangan DBD di RT 14, 15 Desa Mekar Jaya
Authors: Dewi Rasmala , Syafira Rahma , Yulfiyan Assyfa , Garosha Sindi , Putri Imelda Niza Eka , Elvina Nadia 
Published: March 2022

Penyakit DBD (Demam Berdarah Dangue) adalah penyakit demam akut yang disebabkan oleh virus dengue. Pengabdian masyarakat melalui kegiatan penyuluhan ini bertujuan untuk menambah wawasan dan pengetahuan masyarakat mengenai tanda dan gejala penyakit DBD, pencegahan penyakit DBD dengan pemberantasan sarang nyamuk, serta memanfaaatkan tanaman herbal yang berada disekitar masyarakat sebagai upaya pencegahan DBD. Metode yang digunakan adalah ceramah dan diskusi berupa penyampaian materi, pembagian leaflet, dan gotong royong. Hasil dari pengabdian masyarakat menunjukkan menunjukkan adanya peningkatan pemahaman masyarakat. Pengabdian mengenai tanda, gejala serta upaya pencegahan dan penanggulangan DBD.
Kata kunci: DBD, Pengabdian Masyarakat, Desa Mekar Jaya, Tanaman Herbal.
PENGARUH PENGGUNAAN FILLER SLAG NIKEL FENI III PADA CAMPURAN HOT ROLLED SHEET WEARING COURSE (HRS-WC)
Authors: Ressang Vieta Oktaviana Arkos Syahputri , Ngii Edward , Nasrul Nasrul 
Published: March 2022

ABSTRAK Slag nikel adalah limbah B3 yang berasal dari pengolahan biji nikel, proses peleburan biji nikel tersebut menghasilkan limbah-limbah yang berupa slag nikel yang jumlahnya sangat besar, sehingga harus ditangani dan dimanfaatkan dengan baik karena berpotensi menimbulkan masalah lingkungan serta fenomena sosial di masyarakat. Penelitian ini mencoba memanfaatkan slag nikel feni III sebagai filler dalam campuran HRS-WC, untuk mengurangi penggunaan agregat alam, sehingga mendapatkan campuran yang lebih ekonomis dan diharapkan dapat menambah kualitas dari lapis perkerasan HRS-WC.Untuk mengetahui kinerja campuran perkerasan HRS-WC dengan menggunakan filler slag nikel feni III dan dibandingkan dengan filler abu batu, serta mengetahui kadar aspal optimum pada penggunaan filler slag nikel feni III. Penelitian ini menggunakan 4 variasi kadar filler slag nikel feni III yaitu 0%, 6,7%, 9%, dan 11,2% dengan menggunakan 5 variasi kadar aspal dengan benda uji masing masing variasi 2 buah.Karakteristik marshall dalam campuran HRS-WC pada variasi 0% filler slag nikel feni III didapatkan kadar aspal optimum di 6,263%. Pada variasi 6,7% filler slag nikel feni III tidak didapatkan kadar aspal optimum. Pada variasi 9% filler slag nikel feni III didapatkan kadar aspal optimum di 6,544%. Pada variasi 11,2% filler slag nikel feni III didapatkan kadar aspal optimum di 7,023%. Kata Kunci : HRS-WC, slag nikel feni III, kadar aspal optimum (KAO).ABSTRACT The nickel slag is the B3 waste product derived from the processing of nickel seed, the process of smelting the nickel seed is producing a huge amount of slag nickel waste. Therefore, it must be put to good use because it can potentially cause environmental problems and social phenomena in the community. This research tries to utilize nickel feni III as a filler in the HRS-WC mixture, to reduce the use of natural aggregates, so as to obtain a more economical mixture and is expected to increase the quality of the HRS-WC pavement layer.To find out the performance of the HRS-WC pavement mixture by using the Nickel Feni III slag filler and compared to the rock ash filler, as well as knowing the optimum asphalt content in the use of the Nickel Feni III slag filler. This study uses 4 variations of nickel filler content of Feni III namely 0%, 6.7%, 9%, and 11.2% by using 5 variations of asphalt content with two specimens of each specimen.Marshall characteristics in HRS-WC mixture at 0% variation of Nickel Feni III slag filler obtained optimum asphalt content at 6.263%. In the variation of 6.7% nickel feni III filler slag , no optimum asphalt content was obtained. In the variation of 9% nickel feni III filler slag the optimum asphalt content was obtained at 6.544%. In the variation of 11.2% nickel feni III filler slag, optimum asphalt content was found at 7.023%.Keywords : HRS-WC, Nickel Slag Feni III, The Optimum Asphalt Content (OAC).
SIFAT FISIS DAN MEKANIS KAYU JATI PUTIH ASAL SULTRA
Authors: Aswad Nini H. , Sultan Mufti Amir 
Published: March 2022

ABSTRAK Pengetahuan tentang sifat-sifat mekanik maupun fisik kayu, kita dapat memastikan fungsi spesifik struktural dari kayu. Karena kayu masih menjadi alternatif material yang digunakan dalam pelaksanaan konstruksi di lapangan, maka diperlukan penyelidikan melalui eksperimental di laboratorium jenis kayu yang berasal dari Sulawesi Tenggara yang banyak di hasilkan dan dijual bebas yakni jati putih dengan tujuan adalah mengetahui apakah kayu tersebut dapat digunakan pada konstruksi bangunan dan dapat menentukan kualitas kayu. kondisi aktual pemeriksaan kadar air kayu dan pengujian kuat tekan dan lentur kayu adalah metode pendukung secara terstruktur memberikan gambaran kondisi aktual kayu sebagai bahan konstruksi. Kata Kunci : Uji tekan, uji lentur, Jati putih
EVALUASI KEMAMPUAN STRUKTUR GEDUNG KANTOR DINAS KESEHATAN
Authors: Jasmardin Jasmardin , Aswad Nini H , Ngii Edward , Kadir Abdul 
Published: March 2022

Kekuatan Gedung Kantor Dinas Kesehatan Provinsi Sulawesi Tenggara memiliki dimensi eksisting gedung 2 lantai akan di kembangkan sesuai kebutuhan yakni dengan menambah jumlah lantai menjadi 4 lantai, kajian ini menjelaskan pengaruh kekuatan akibat beban gempa terhadap struktur gedung tersebut dengan bantuan analisis menggunakan SAP 2000 v.12 sehingga dapat di desain kembali dimensi pada tulangan struktur pelat, balok dan kolom pada lantai 3 dan lantai 4, dari analisis yang dilakukan menunjukkan bahwa struktur exsisting bangunan yang terdiri dari kolom dan balok induk lantai 1 dan lantai 2 masih mampu menahan beban tambahan akibat penambahan jumlah lantai.
Effects of climate on bank default
Authors: Oliveira Guilherme Resende 
Published: March 2022

Developing countries are more vulnerable to the consequences of climate change. The access to credit has been highlighted as crucial to the investment in adaptation strategies and to build resilient economies, but bank lending behavior in response to climatic shocks is still not well understood. The demand for credit is expected to increase in periods of extreme climate events, but loan delinquency rates would likely go up as well. In recent decades, Brazil has already experienced unusual climate variability with severe droughts in the Northeastern region, the most populous semiarid area in the world. The Bank of the Northeast (BNB), a public bank that has been used to implement local development policies, has lent over US$ 20 billion since the earmarking of funds for regional development in the Constitution of 1988. This study examines the impact of climatic shocks on the BNB’s credit operations and delinquency rates when several climatic events occurred over the period of 2002-2013. The econometric regressions method was used with fixed-effects panel data and its estimates indicate that deviations of temperature and precipitation from their annual mean increased default rates considerably. One of the factors that affects bank defaults may be the reduction in agricultural production, since default rates are higher in this sector, which suffers from the income reduction of producers whom are affected by these climate variations.
Metal–Insulator Transition Driven by Traps in 2D WSe2 Field‐Effect Transistor
Authors: Ali Fida , Ali Nasir , Taqi Muhammad , Ngo Tien Dat , Lee Myeongjin , Choi Hyungyu , Park Won‐Kyu , Hwang Euyheon , Yoo Won Jong 
Published: March 2022

AbstractLocalized trap density (Dt) at the 2D channel–gate dielectric interface and its relative strength to carrier–carrier interactions depending on the thickness of the 2D channel can determine the nature of a metal–insulator transition (MIT) in 2D materials. Here, the MIT occurring in WSe2 devices is systematically analyzed by varying the WSe2 thickness from ≈20 nm to monolayer to explore the effects of Dt on MIT. The corresponding critical carrier density increases from ≈8.30 × 1011 to 9.45 × 1012 cm–2 and Dt from ≈6.02 × 1011 to 1.13 × 1013 cm–2 eV–1 as WSe2 thickness decreases from ≈20 nm to monolayer. These large increments in Dt with decreasing thickness of WSe2 induce a strong potential fluctuation in the band of WSe2, causing charge density inhomogeneity in the system, which attributed to tuning the MIT. The critical percolation exponent is strongly dependent on WSe2 thickness with an excellent agreement between the transport data and percolation theory achieved from thinner WSe2 devices, while the transport data measured from multilayer WSe2 devices does not obey the percolation theory. These results suggest that the nature of MIT strongly depends on the WSe2 channel thickness and corresponding unscreened charge impurity and strength of Dt at the interface.
The Society for Craniofacial Genetics and Developmental Biology 44th Annual Meeting
Authors: Brugmann Samantha A. , Merrill Amy E. , Saint‐Jeannet Jean‐Pierre , Stottmann Rolf W. , Clouthier David E. 
Published: March 2022

AbstractThe Society for Craniofacial Genetics and Developmental Biology (SCGDB) held its 44th Annual Meeting in a virtual format on October 18–19, 2021. The SCGDB meeting included presentation of the SCGDB Distinguished Scientists in Craniofacial Research Awards to Drs. Paul Trainor and Jeff Bush and four scientific sessions on the genomics of craniofacial development, craniofacial morphogenesis and regeneration, translational craniofacial biology and signaling during craniofacial development. The meeting also included workshops on professional development for faculty and trainees, National Institutes of Health (NIH)/National Institute of Craniofacial and Dental Research funding and usage of Genomics Software, as well as two poster sessions. An exhibitor booth run by FaceBase was also present to facilitate the upload and download of datasets relevant to the craniofacial community. Over 200 attendees from 12 countries and 23 states, representing over 80 different scientific institutions, participated. This diverse group of scientists included cell biologists, developmental biologists, and clinical geneticists. Although the continuing COVID‐19 pandemic forced a virtual meeting format for a second year in a row, the meeting platform provided ample opportunities for participant interactions and discussions, thus strengthening the community.
Layer Shape LiFePO4 Obtained by Powder Extrusion Molding as Solid Boosters for Ferro/Ferricyanide Catholyte in Semisolid Redox Flow Battery: Effect of Porosity and Shape
Authors: Vivo‐Vilches Jose F. , Vázquez‐Navalmoral Álvaro , de la Torre‐Gamarra Carmen , Cebollada Jesús , Várez Alejandro , Levenfeld Belén 
Published: March 2022

AbstractPowder extrusion molding is proposed to fabricate ceramic LiFePO4 layers (0.5–1.0 mm thickness) as solid booster for ferricyanide electrolyte in semisolid redox flow battery. In some extruded layers, the binder is partially decomposed, while in others it is completely removed and, afterwards, the material is sintered, so materials with different porosity and dimensions are obtained. After characterizing the materials, the kinetics for the reaction with ferricyanide is evaluated, being the binder‐less materials the ones which react faster and reach larger degrees of oxidation. For the material with 1.0 mm thick comparable results to the ones already published are obtained (69 % capacity for LiFePO4 compared to the theoretical value). In the case of the 0.5 mm thick sintered solid, an outstanding performance is achieved, reaching almost the theoretical capacity (94 %) with a very high coulombic efficiency (>99 %) at 1 mA cm−2, results that were only obtained at much lower current densities in previous works.
Molecular biomarkers in cardio‐oncology: Where we stand and where we are heading
Authors: Vasileiou Panagiotis V. S. , Siasos Gerasimos , Gorgoulis Vassilis G. 
Published: March 2022

AbstractUntil recently, cardiotoxicity in the setting of a malignant disease was attributed solely to the detrimental effects of chemo‐ and/or radio‐therapy to the heart. On this account, the focus was on the evaluation of well‐established cardiac biomarkers for the early detection of myocardial damage. Currently, this view has been revised. Cardiotoxicity is not restricted to a single organ but instead affects the endothelium as a whole. Indeed, it has come into light that not only cancer therapy but also malignant cells per se can impair the cardiovascular system, through a paracrine and endocrine mode of action. Even more intriguingly, a clear interplay between molecular pathways involved in cancer and cardiovascular disease has become prevalent, suggesting a common nominator that governs the pathophysiology of these two entities. Taken together, our strategy in the quest of novel biomarkers in the emerging field of cardio‐oncology should be critically reshaped.
Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia
Authors: Park Kibeom , Yoo Hee‐Seop , Oh Chang‐Kyu , Lee Joo Rak , Chung Hee Jin , Kim Ha‐Neul , Kim Soo‐Hyun , Kee Kyung‐Mi , Kim Tong Yoon , Kim Myungshin , Kim Byung‐Gyu , Ra Jae Sun , Myung Kyungjae , Kim Hongtae , Han Seung Hun , Seo Min‐Duk , Lee Yoonsung , Kim Dong‐Wook 
Published: March 2022

AbstractCobll1 affects blast crisis (BC) progression and tyrosine kinase inhibitor (TKI) resistance in chronic myeloid leukemia (CML). PACSIN2, a novel Cobll1 binding protein, activates TKI‐induced apoptosis in K562 cells, and this activation is suppressed by Cobll1 through the interaction between PACSIN2 and Cobll1. PACSIN2 also binds and inhibits SH3BP1 which activates the downstream Rac1 pathway and induces TKI resistance. PACSIN2 competitively interacts with Cobll1 or SH3BP1 with a higher affinity for Cobll1. Cobll1 preferentially binds to PACSIN2, releasing SH3BP1 to promote the SH3BP1/Rac1 pathway and suppress TKI‐mediated apoptosis and eventually leading to TKI resistance. Similar interactions among Cobll1, PACSIN2, and SH3BP1 control hematopoiesis during vertebrate embryogenesis. Clinical analysis showed that most patients with CML have Cobll1 and SH3BP1 expression at the BC phase and BC patients with Cobll1 and SH3BP1 expression showed severe progression with a higher blast percentage than those without any Cobll1, PACSIN2, or SH3BP1 expression. Our study details the molecular mechanism of the Cobll1/PACSIN2/SH3BP1 pathway in regulating drug resistance and BC progression in CML.
Predictive Factors for Postoperative Opioid Use in Elective Endoscopic Endonasal Skull Base Surgery
Authors: Potter Tamia , Soni Pranay , Krywyj Maria , Petitt Jordan , Jarmula Jakub , Obiri‐Yeboah Derrick , Oyem Precious , Momin Arbaz , Easley Kathryn , Sindwani Raj , Woodard Troy , Recinos Pablo F. , Kshettry Varun R. 
Published: March 2022

ObjectiveIn 2017, the United States opioid epidemic was declared a public health emergency. Increased efforts have been made to understand and reduce patient opioid use in neurosurgery. However, the factors associated with postoperative opioid use remain understudied in endoscopic endonasal skull base surgery (EESBS). We identified the demographic and surgical factors associated with postoperative opioid use in EESBS.MethodsA retrospective review was conducted of patients who underwent elective EESBS between January 2015 and December 2020. Patient demographics, relevant clinical history, and operative data were collected and analyzed. Total opioid use was calculated 24, 48, and 72 hours postoperatively. Multivariable linear regression analyses were performed to identify factors associated with opioid use.ResultsThere were 454 patients included. A history of anxiety/depression and younger patient age were associated with a significant increase in opioid use at 24 (28.2 MME, p < 0.001), 48 (53.4 MME, p < 0.001), and 72 (89.4 MME, p < 0.001) hours after surgery. Nasoseptal flap use was significantly associated with increased opioid use at 24 (12.8 MME, p < 0.49) and 48 (19.6 MME, p < 0.048) h postoperatively while controlling for intraoperative variables and surgical approach (trans‐sellar vs. expanded). No significant association was observed for patient sex, history of migraines, preoperative opioid use, length of surgery, or surgical approach.ConclusionIn patients undergoing EESBS, patient history of anxiety/depression, younger patient age, and nasoseptal flap use are associated with increased postoperative opioid use. Knowledge of these risk factors may guide perioperative prescribing patterns to both adequately control postoperative pain and reduce opioid use.Level of Evidence4 Laryngoscope, 133:494–499, 2023
Domain Structures and Temperature Induced Phase Transitions in Perovskite Molecular 3‐Ammonioquinuclidinium‐NH4Cl3
Authors: Gao Jinghan , Lv Qianrui , Li Feihui , Guo Junjie 
Published: March 2022

AbstractMolecular ferroelectric 3‐ammonioquinuclidinium‐NH4Cl3 (3‐AP‐NH4Cl3) crystals were prepared. DSC‐CP‐TG curves were studied and a small endothermic peak was discovered at 146 °C without obvious mass change. Dielectric properties were measured and a sharp peak was found at 146 °C in the dielectric constant versus temperature curve. Temperature‐dependent domain evolution was observed in situ by polarized light microscopy (PLM). The extinction‐variation temperature range agreed well with the phase transition temperature that takes place in the dielectric measurement. This result further confirmed a phase transition from ferroelectric phase to paraelectric phase. A schematic diagram is also established to clarify the temperature induced phase transition. The shape change of free energy curve caused by temperature may result in the phase transition.
Structure‐Based Optimization of Novel Farnesoid X Receptor Agonist for the Treatment of Acetaminophen‐Induced Liver Injury
Authors: Feng Dongchan , Tang Yan , Qiu Huawei , Zhang Li , Wu Dan 
Published: March 2022

AbstractFarnesoid X receptor (FXR) plays an important role in regulating glucolipid metabolism, detoxification, and inflammation in liver. Thus, FXR has huge potential on several liver diseases, including drug‐induced liver injury, fibrosis, and fatty liver. In this study, we performed a structure‐based drug design strategy to optimize the previous reported FXR agonist N‐(2‐methoxy‐4‐nitrophenyl)‐2‐((2‐(2‐oxopyrrolidin‐1‐yl)phenyl)amino)acetamide (1). After structure‐based drug design, the optimal compound, 3‐(2‐((2‐(2‐oxopyrrolidin‐1‐yl)phenyl)amino)acetamido)benzoic acid (2, EC50=2.43 μM), was identified by displacing the potentially toxic nitro group of compound 1 with carboxylic acid to obtain new ionic bond with His294. Compound 2 revealed considerable activity on FXR, and exerts best therapeutic effects on alleviating acetaminophen‐induced liver damages in this series by up‐regulation of FXR‐related gene expression in vivo. In summary, these results suggest that compound 2 is a promising FXR agonist suitable for further evaluation.
Machine learning accelerated calculation and design of electrocatalysts for CO2 reduction
Authors: Sun Zhehao , Yin Hang , Liu Kaili , Cheng Shuwen , Li Gang Kevin , Kawi Sibudjing , Zhao Haitao , Jia Guohua , Yin Zongyou 
Published: March 2022

AbstractIn the past decades, machine learning (ML) has impacted the field of electrocatalysis. Modern researchers have begun to take advantage of ML‐based data‐driven techniques to overcome the computational and experimental limitations to accelerate rational catalyst design. Hence, significant efforts have been made to perform ML to accelerate calculation and aid electrocatalyst design for CO2 reduction. This review discusses recent applications of ML to discover, design, and optimize novel electrocatalysts. First, insights into ML aided in accelerating calculation are presented. Then, ML aided in the rational design of the electrocatalyst is introduced, including establishing a data set/data source selection and validation of descriptor selection of ML algorithms validation and predictions of the model. Finally, the opportunities and future challenges are summarized for the future design of electrocatalyst for CO2 reduction with the assistance of ML.