bluuebunny/crossref_metadata_2025_split huggingface dataset:
Willingness to join community based health insurance among households in South Wollo, Northeast Ethiopia: A community-based cross-sectional study
Authors: Biset Wagaw Gebeyaw , Tadesse Abay Woday , Ambaye Getahun Yeshiwas 
Published: February 2022

Background
Poor health care financing remains a major challenge to health service utilization among the lower socioeconomic society. Consequently, countries have designed different health insurance programs to overcome financial barriers against health services utilization. Similarly, Ethiopia has been implementing community-based health insurance programs since 2011 to improve health care financing system. However, only a small number of people are enrolled which might be attributed to lack of willingness towards the program and the reasons for this remained under reported. This study was intended to examine willingness to join the community-based health insurance program and its associated factors in South Wollo, Northeast Ethiopia.

Method
A community-based cross-sectional study was conducted among 421 households. A multistage systematic random sampling technique was employed to recruit the study households. Data were entered into EpiData version 3.1 and was exported into SPSS version 24.0 for analysis. Bivariable and multivariable logistic regression analysis with a backward elimination method was performed to identify the determinants of willingness to join community-based health insurance. Finally, a statistically significant level was declared at a p-value of less than 0.05.

Results
Two hundred and ninety-three [73.6% (95%CI:68.8%-77.9%)] households were willing to join community-based health insurance programs. Being male headed household (AOR:0.2, 95%CI: 0.07–0.58), being a member of Idir (AOR:0.46, 95%CI: 0.25-.84), absence of chronic illness in the household (AOR: 0.31, 95%CI: 0.13–0.77), and family size < 4 (AOR: 0.18, 95% CI:0.08–0.41) were barriers to join community-based health insurance program whereas rural residency (AOR:1.9, 95% CI: 1.09–3.32), perceived quality health services (AOR:2.96, 95%CI:1.4–6.24), and having positive attitude (AOR:4.1, 95%CI:2.32–7.22) and good knowledge to programs (AOR:2.62, 95%CI:1.43–4.8) were enabling factors.

Conclusion
Nearly three-fourths of the households were willing to join community-based health insurance programs. However, different household and health service-related factors affected their willingness. The ministry of health with the regional and woreda health offices should work towards improving the quality of health services, conduct program advocacy and community sensitization towards the program, and build trust with the community.
Evaluation of antimicrobial photodynamic therapy with acidic methylene blue for the treatment of experimental periodontitis
Authors: de Almeida Juliano Milanezi , Matheus Henrique Rinaldi , Sendão Alves Breno Edson , Rodrigues Gusman David Jonathan , Nagata Maria José Hitomi , de Abreu Furquim Elisa Mara , Ervolino Edilson 
Published: February 2022

Objective
To investigate the security and effectiveness of antimicrobial photodynamic therapy (aPDT) with a citric acid-based methylene blue (MB) on the periodontal repair following the treatment of ligature-induced experimental periodontitis (EP) in rats.

Material and methods
Were used 120 male rats, randomly divided into 4 experimental groups (n = 30): no treatment (NT), SRP alone (SRP), SRP plus aPDT using conventional MB pH 7.0 (aPDT-pH7), SRP plus aPDT using acidic MB pH 1.0 (aPDT-pH1). EP was induced at day 0 by the placement of a ligature around the mandibular left first molars. Ten animals per group/period were euthanized at 14, 22 and 37 days. Histopathological, histometric (percentage of bone in the furcation [PBF]) and immunohistochemical (for tartrate-resistant acid phosphatase [TRAP] and osteocalcin [OCN]) analyses were performed. Data were statistically analyzed.

Results
aPDT-pH1 showed the highest PBF as compared with the other treatments. Collectively, tissues’ reaction to both dyes were controlled and healthy for the periodontium. Both aPDT protocols reduced the extent and intensity of the local inflammatory response, reduced the alveolar bone resorption, and promoted a better structural arrangement of the connective tissue as compared with SRP. TRAP expression was downregulated while OCN expression was upregulated by aPDT as compared with SRP alone.

Conclusion
Our data implicate that the novel MB pH 1.0 is as safe as the conventional MB for use in aPDT and raises its additional benefit of increasing the amount of alveolar bone in the furcation.
Views and experiences of maternal healthcare providers regarding influenza vaccine during pregnancy globally: A systematic review and qualitative evidence synthesis
Authors: Alhendyani Fatemah , Jolly Kate , Jones Laura L. 
Published: February 2022

Background
The World Health Organization (WHO) recommends that pregnant women receive influenza vaccination; however, uptake of the vaccine remains low. Maternity health care professionals (MHCPs) play an important role in motivating pregnant women to receive the influenza vaccine. However, factors such as MHCPs’ views and knowledge about the vaccine, and time constraints due to workload may influence MHCPs’ practices and opinions about women receiving the influenza vaccine during pregnancy. To date, the qualitative evidence exploring MHCPs’ views and experiences around influenza vaccine uptake in pregnant women has not been synthesised.

Aim
To systematically review and thematically synthesise qualitative evidence that explores the views and experiences of MHCPs involved in the provision of the maternal influenza vaccine worldwide.

Methods
Five databases (MEDLINE, EMBASE, PsycINFO, CINAHL, Web of Science) were searched, supplemented with searches of included paper reference lists and grey literature. Study selection was conducted by up to three researchers applying pre-specified inclusion/exclusion criteria. Quality assessment was undertaken, data were extracted, coded and synthesised to develop descriptive and analytical themes.

Results
Eight studies involving 277 participants were included. Seventeen descriptive themes were interpreted, embedded within six analytical themes. MHCPs perceived that maternal influenza vaccination delivery can be facilitated by trusting relationships, good communication, knowledge about the vaccine leading to confidence in recommending vaccine, electronic vaccination prompts, and presence of national guidelines. However, workload, time constraints, MHCP’s perception of pregnant women’s concerns, and social/cultural/environmental influences could prevent the likelihood of delivery of influenza vaccine. Knowledgeable MHCPs who were regularly updated about vaccination based on scientific evidence were more confident when discussing and recommending the influenza vaccine to pregnant women. In addition, the presence of national policies and guidelines and electronic prompts for maternal influenza vaccination would enhance the delivery of the vaccine.

Conclusion
Our findings suggest that approaches to enhance the vaccination uptake rate in pregnant women include addressing MHCPs barriers to discussing influenza vaccination through education, sufficient time for discussions, and electronic prompts about vaccination, as well as evidence based local and national guidelines.
Dynamics of Triatoma infestans populations in the Paraguayan Chaco: Population genetic analysis of household reinfestation following vector control
Authors: Rojas de Arias Antonieta , Messenger Louisa Alexandra , Rolon Miriam , Vega María Celeste , Acosta Nidia , Villalba Cesia , Marcet Paula L. 
Published: February 2022

Background
Although domestic infestations by Triatoma infestans have been successfully controlled across Latin America, in areas of the Gran Chaco region, recurrent post-spraying house colonization continues to be a significant challenge, jeopardizing Chagas disease vector control and maintaining active Trypanosoma cruzi transmission.

Methodology/Principal findings
To investigate the dynamics of triatomine reinfestation in a rural area of the Paraguayan Chaco, genetic characterization (based on 10 microsatellite loci and cytochrome B sequence polymorphisms) was performed on baseline and reinfestant T. infestans (n = 138) from four indigenous communities and adjacent sylvatic sites. House quality and basic economic activities were assessed across the four communities. Significant genetic differentiation was detected among all baseline triatomine populations. Faster reinfestation was observed in the communities with higher infestation rates pre-spraying. Baseline and reinfestant populations from the same communities were not genetically different, but two potentially distinct processes of reinfestation were evident. In Campo Largo, the reinfestant population was likely founded by domestic survivor foci, with reduced genetic diversity relative to the baseline population. However, in 12 de Junio, reinfestant bugs were likely derived from different sources, including survivors from the pre-spraying population and sympatric sylvatic bugs, indicative of gene-flow between these habitats, likely driven by high human mobility and economic activities in adjacent sylvatic areas.

Conclusions/Significance
Our results demonstrate that sylvatic T. infestans threatens vector control strategies, either as a reinfestation source or by providing a temporary refuge during insecticide spraying. Passive anthropogenic importation of T. infestans and active human interactions with neighboring forested areas also played a role in recolonization. Optimization of spraying, integrated community development and close monitoring of sylvatic areas should be considered when implementing vector control activities in the Gran Chaco.
Understanding how individualised physiotherapy or advice altered different elements of disability for people with low back pain using network analysis
Authors: Liew Bernard X. W. , Ford Jon J. , Briganti Giovanni , Hahne Andrew J. 
Published: February 2022

Purpose
The Oswestry Disability Index (ODI) is a common aggregate measure of disability for people with Low Back Pain (LBP). Scores on individual items and the relationship between items of the ODI may help understand the complexity of low back disorders and their response to treatment. In this study, we present a network analysis to explore how individualised physiotherapy or advice might influence individual items of the ODI, and the relationship between those items, at different time points for people with LBP.

Methods
Data from a randomised controlled trial (n = 300) comparing individualised physiotherapy versus advice for low back pain were used. A network analysis was performed at baseline, 5, 10, 26 and 52 weeks, with the 10 items of the Oswestry Disability Index modelled as continuous variables and treatment group (Individualised Physiotherapy or Advice) modelled as a dichotomous variable. A Mixed Graphical Model was used to estimate associations between variables in the network, while centrality indices (Strength, Closeness and Betweenness) were calculated to determine the importance of each variable.

Results
Individualised Physiotherapy was directly related to lower Sleep and Pain scores at all follow-up time points relative to advice, as well as a lower Standing score at 10-weeks, and higher Lifting and Travelling scores at 5-weeks. The strongest associations in the network were between Sitting and Travelling at weeks 5 and 26, between Walking and Standing at week 10, and between Sitting and Standing scores at week 52. ODI items with the highest centrality measures were consistently found to be Pain, Work and Social Life.

Conclusion
This study represents the first to understand how individualised physiotherapy or advice differentially altered disability in people with LBP. Individualised Physiotherapy directly reduced Pain and Sleep more effectively than advice, which in turn may have facilitated improvements in other disability items. Through their high centrality measures, Pain may be considered as a candidate therapeutic target for optimising LBP management, while Work and Socialising may need to be addressed via intermediary improvements in lifting, standing, walking, travelling or sleep. Slower (5-week follow-up) improvements in Lifting and Travelling as an intended element of the Individualised Physiotherapy approach did not negatively impact any longer-term outcomes.

Trials registration
ACTRN12609000834257.
Pertussis outbreak investigation in Northwest Ethiopia: A community based study
Authors: Yeshanew Addisu Gize , Lankir Damtie , Wondimu Jimmawork , Solomon Samrawit 
Published: February 2022

Background
Pertussis or whooping cough is a vaccine-preventable, highly contagious, respiratory illness caused by Bordetella pertussis or Bordetella parapertussis. Infants and young children have remained most susceptible to pertussis-related morbidity and mortality. The aim of this study was to investigate pertussis infection and analyze the associated factors involved in the occurrence of the cases.

Methods
Community-based case-control was conducted in Dahena district, Northwest Ethiopia, from March 27—April 30, 2019. All cases ages 1–18 years old were identified by using the clinical standard case definition of pertussis adopted from World Health Organization (WHO). Data was collected using a structured questionnaire via face-to-face interviews. The data collected was cleaned, coded and entered into Epi info version 7.2.1.0 and exported to SPSS version 23 for statistical analysis. Bivariable and multivariable logistic regression analysis were employed to identify predictors. Factors with a p-value of < 0.05 were considered as independent risk factors of pertussis infection in multivariable logistic regression analysis.

Result
A total of 122 pertussis cases were enrolled from the Azila cluster of the Dahena district. Of these figures, 64 (52.5%) were females. The overall attack rate (AR) of pertussis cases in the cluster was 8.6/10000 population. The sex-specific AR of females was 8.9/10000 population. The multivariable logistic regression analysis showed that; being unvaccinated 4.17 (AOR, 4.17, 95% CI, 1.914–9.091), contact to cases 2.93 (AOR: 2.93, 95% CI 1.223–6.996), and living in a house with no window 2.6 (AOR: 2.6(95% CI 1.071 to 6.322) were the independent significantly risk factors for pertussis infection.

Conclusion
The contributing factor for pertussis infection was associated with case-contact, living in the house without windows and being unvaccinated. Wag Hemra Zone and Dahena district health office should encourage the vaccination activities of the cluster health center and awareness for the community should be practiced to limit disease transmission.
Critical review and meta-analysis of biological variation estimates for tumor markers
Authors: Marques-Garcia Fernando , Boned Beatriz , González-Lao Elisabet , Braga Federica , Carobene Anna , Coskun Abdurrahman , Díaz-Garzón Jorge , Fernández-Calle Pilar , Perich Maria Carmen , Simon Margarida , Jonker Niels , Aslan Berna , Bartlett William Alexander , Sandberg Sverre , Aarsand Aasne K. 
Published: February 2022

Abstract

Objectives
Biological variation data (BV) can be used for different applications, but this depends on the availability of robust and relevant BV data. In this study, we aimed to summarize and appraise BV studies for tumor markers, to examine the influence of study population characteristics and concentrations on BV estimates and to discuss the applicability of BV data for tumor markers in clinical practice.

Methods
Studies reporting BV data for tumor markers related to gastrointestinal, prostate, breast, ovarian, haematological, lung, and dermatological cancers were identified by a systematic literature search. Relevant studies were evaluated by the Biological Variation Data Critical Appraisal Checklist (BIVAC) and meta-analyses were performed for BIVAC compliant studies to deliver global estimates of within-subject (CVI) and between-subject (CVG) BV with 95% CI.

Results
The systematic review identified 49 studies delivering results for 22 tumor markers; four papers received BIVAC grade A, 3 B, 27 C and 15 D. Out of these, 29 CVI and 29 CVG estimates met the criteria to be included in the meta-analysis. Robust data are lacking to conclude on the relationship between BV and different disease states and tumor marker concentrations.

Conclusions
This review identifies a lack of high-quality BV studies for many tumor markers and a need for delivery of BIVAC compliant studies, including in different disease states and tumor marker concentrations. As of yet, the state-of-the-art may still be the most appropriate model to establish analytical performance specifications for the majority of tumor markers.
Ideal corrosion inhibitors: a review of plant extracts as corrosion inhibitors for metal surfaces
Authors: Murungi Pearl Isabellah , Sulaimon Aliyu Adebayo 
Published: February 2022

Abstract
Corrosion, a gradual destruction of metals as they react to their environment, is a daunting issue faced by the oil and gas industry since it has negative impacts on both life and industry applications. Attempts to tackle this problem have involved a myriad of techniques among which, corrosion inhibitors have been found to be the most effective. Corrosion inhibitors adsorb onto metallic surfaces and insulate them from deterioration. Plants being green and abundant in nature, offer a cost-effective replacement to toxic, chemical inhibitors on the market. Investigations of several plant extracts using different variables to quantify their effectiveness reveal that most of them exhibit an excellent inhibition potential, usually above 90%. These outstanding results prove their efficiency compared to traditional methods and necessitate further studies so as to enable implementation on large scale.
Struktureller Wandel rechts motivierter Brandstiftungstäter*innen?
Authors: Berberich Jana , Laube Max 
Published: February 2022

Zusammenfassung
Der vorliegende Beitrag analysiert Wandlungsprozesse im Deliktsfeld rechts motivierter Brandstiftungen in Deutschland im Zeitraum von 2010 bis 2017. Der Fokus liegt hierbei auf Tatverdächtigen bzw. Täter*innen und es wird die Frage beantwortet, wie sich der Wandel der Täter*innenstruktur in den vergangenen Jahren im genannten Deliktsbereich konkret ausgestaltet hat. Als empirische Bezugspunkte dienen zwei laufende Forschungsprojekte, die sich mit unterschiedlichen methodischen Zugängen – einerseits der statistischen Analyse von Tatverdächtigendaten der Polizei, andererseits der auf Täter*innen bezogenen Aktenanalyse – der obigen Forschungsfrage widmen. Die empirischen Ergebnisse belegen einen drastischen Wandel der Tatverdächtigen- bzw. Täter*innenstruktur im Untersuchungszeitraum. So lässt sich ein deutlicher Anstieg des Anteils an weiblichen Tatverdächtigen konstatieren. Auch die für rechte Gewalt eher untypische Altersgruppe der Tatverdächtigen über 30 Jahre hat an Relevanz gewonnen. Darüber hinaus hat der Anteil von Gruppentaten im Zeitverlauf ab – und der Anteil an alleinhandelnden Täter*innen zugenommen. Da über eine Analyse der Tatmittel auf einen hohen Planungsgrad der Taten geschlossen werden kann, lässt sich bilanzieren, dass sich im Zuge der sog. »Flüchtlingskrise« neue, eher der »Mitte der Gesellschaft« zugehörige Tätergruppen gebildet haben, die analytisch nicht mehr in das etablierte Forschungsraster der spontan verübten Jugendgewalt passen.
Enhancement in tissue paper production by optimizing creeping parameters such as application of various blade material (MOC) and creep pocket geometry
Authors: Jain Sanjeev Kumar , Dutt Dharam , Jain R. K. 
Published: February 2022

Abstract
This study is focused on the development of ultrasoft facial grade tissue paper of 12.5 gsm with superior quality in terms of handfeel softness alongside enhanced productivity.
To sustain in the tissue paper business, industries needs to focus in such a way that productivity should be increased with excellent product quality. Tissue industries generally loose huge productivity as well as deviation is observed in high quality low gsm facial grade tissue paper in terms of quality. This is owing to vague understanding about the creeping geometry where creep pocket angle, blade grind angle, blade MOC play a significant role to improve the productivity and produce excellent product quality. This experimental study would bridge for better understanding of impact of creping blade material and crepe blade geometry on productivity and quality of tissue paper.
In this experimental study, two types of creping blade material– carbon steel and ceramic were used. Machine runability, mechanical properties of developed facial grade tissue paper was minutely analysed. It was found that while using ceramic blade, downtime reduced by 86.8 % while the production was enhanced by 10 % indicating better machine runnability with ceramic blade. Thereafter, the blade holder angle was altered to 17°, 18° and 19° along with alterations of bevel angle to 75°, 80°, 85° and 90°. All the mechanical properties of developed facial grade tissue paper was investigated and analysed. The outcome of the study indicated that by using ceramic tip creping blade with 17° blade holder angle and bevel angle at 80°, ultrasoft, high bulk facial grade tissue paper can be produced with much improved machine runnability i. e. downtown reduced by 85 % on account of blade changing frequency and production enhanced by 10 %.
Speaking one’s mind: the sign as subject of interpretation in the manuscripts of Charles S. Peirce, between the theories of rhetoric and communication
Authors: Haase Fee 
Published: February 2022

Abstract
The name Charles Sanders Peirce (1839–1914) is associated with the science of signs called semiotics, which studies the sign as the carrier of meaning that is placed in the center of his work. Peirce developed a system of concepts that describe how the sign as such is understood by the mind. For the conditions of its interpretations Peirce established various so-called interpretants for the explanation of signs associated with the utterer and interpreter and a shared process that enables the communication between communicators. Further to the renovation of the theory of rhetoric and communication, we show that medium and communication must be understood within the framework of his theory in association to the sign and the object. Throughout his manuscripts the triads of his concepts are realized in the text in rhetorical tricola as terms of his philosophy. In comparison to Aristotle’s Rhetoric, which employed the sign as a means for reasoning, we will show how Peirce developed techniques of reasoning based on Aristotle’s work and his model of mental understanding of the sign while foreshadowing a theory of communication that aims at describing the exchange of information in a model.
Elemente der „Fabrik der Zukunft“
Authors: Schäfer Simon F. , Gorke Nils T. , Cevirgen Cihan , Park Yeong-Bae , Nyhuis Peter 
Published: February 2022

Abstract
Die Anforderungen an zukünftige Fabriken wachsen im Zuge der immer komplexeren Vernetzung von Wertschöpfungsprozessen stetig. Dieser erhöhte Druck erfordert eine erhöhte digitale Transparenz, um mit den gesteigerten Herausforderungen, insbesondere im Zielfeld Nachhaltigkeit, mitzuhalten. Die Themen Digitale Fabrik, Industrie 4.0 und Building Information Modeling sind zunehmend im Einsatz in den jeweiligen Planungsdomänen einer Fabrik und leisten Ihren eigenen Beitrag zur Beherrschung der Komplexität und Verbesserung der Planungsergebnisse. Offen ist, wie diese Elemente strukturiert zusammengeführt werden können, damit eine gesamtheitliche Lösung geplant, gestaltet und gesteuert werden kann. Der vorliegende Beitrag geht dieser Frage nach und postuliert eine Vision der „Fabrik der Zukunft“. Im ersten Teil dieser Beitragsreihe werden die Grundlagen der Digitalen Fabrik, Industrie 4.0 und BIM dargestellt.