bluuebunny/crossref_metadata_2025_split huggingface dataset:
Precursor identification for strong flares based on anomaly detection algorithm
Authors: Wang Jingjing , Luo Bingxian , Liu Siqing 
Published: October 2022

In this study, we assume that the magnetic configuration of active regions (ARs) in quiet periods has certain similarities and can be considered “normal” features. While there are some other magnetic features of active regions that are related to strong flares, they can be considered the precursor of strong flares and “anomaly” features. Our study aims to identify those “anomalies” and apply them in strong-flare forecasting. An unsupervised auto-encoder network has been used to understand and memorize these “normal” features, and then, based on the mean squared errors between the pictures of the ARs and the corresponding reconstructed pictures derived by the network, an anomaly detection algorithm has been adopted to identify the precursor for strong flares and develop a strong-flare classification model. The strong-flare classification model reaches an F1 score of 0.8139, an accuracy of 0.8954, a recall of 0.8785, and a precision of 0.7581. Moreover, for those correctly predicted strong-flare events (94 M-class flares and above), the model reaches an average first warning time of 45.24 h. The results indicate that the anomaly detection algorithm can be used in precursor identification for strong flares and help in both improving strong-flare prediction accuracy and enlarging the time in advance. Also, the obtained average maximum warning period for strong-flare prediction (nearly 2 days) will be useful for future applications for space-weather solar flare prediction.
A more novel and powerful prognostic gene signature of lung adenocarcinoma determined from the immune cell infiltration landscape
Authors: Ma Chao , Li Feng , He Zhanfeng , Zhao Song 
Published: October 2022

BackgroundLung adenocarcinoma (LUAD) is the leading histological subtype of lung cancer worldwide, causing high mortality each year. The tumor immune cell infiltration (ICI) is closely associated with clinical outcome with LUAD patients. The present study was designed to construct a gene signature based on the ICI of LUAD to predict prognosis.MethodsDownloaded the raw data of three cohorts of the TCGA-LUAD, GSE72094, and GSE68465 and treat them as training cohort, validation cohort one, and validation cohort two for this research. Unsupervised clustering detailed grouped LUAD cases of the training cohort based on the ICI profile. The univariate Cox regression and Kaplan–Meier was adopted to identify potential prognostic genes from the differentially expressed genes recognized from the ICI clusters. A risk score-based prognostic signature was subsequently developed using LASSO-penalized Cox regression analysis. The Kaplan-Meier analysis, Cox analysis, ROC, IAUC, and IBS were constructed to assess the ability to predict the prognosis and effects of clinical variables in another two independent validation cohorts. More innovatively, we searched similar papers in the most recent year and made comprehensive comparisons with ours. GSEA was used to discover the related signaling pathway. The immune relevant signature correlation identification and immune infiltrating analysis were used to evaluate the potential role of the signature for immunotherapy and recognize the critical immune cell that can influence the signature's prognosis capability.ResultsA signature composed of thirteen gene including ABCC2, CCR2, CERS4, CMAHP, DENND1C, ECT2, FKBP4, GJB3, GNG7, KRT6A, PCDH7, PLK1, and VEGFC, was identified as significantly associated with the prognosis in LUAD patients. The thirteen-gene signature exhibited independence in evaluating the prognosis of LUAD patients in our training and validation cohorts. Compared to our predecessors, our model has an advantage in predictive power. Nine well know immunotherapy targets, including TBX2, TNF, CTLA4, HAVCR2, GZMB, CD8A, PRF1, GZMA, and PDCD1 were recognized correlating with our signature. The mast cells were found to play vital parts in backing on the thirteen-gene signature's outcome predictive capacity.ConclusionsCollectively, the current study indicated a robust thirteen-gene signature that can accurately predict LUAD prognosis, which is superior to our predecessors in predictive ability. The immune relevant signatures, TBX2, TNF, CTLA4, HAVCR2, GZMB, CD8A, PRF1, GZMA, PDCD1, and mast cells infiltrating were found closely correlate with the thirteen-gene signature's power.
Three-dimensional computed tomography reconstruction in video-assisted thoracoscopic segmentectomy (DRIVATS): A prospective, multicenter randomized controlled trial
Authors: Niu Zhenyi , Chen Kai , Jin Runsen , Zheng Bin , Gong Xian , Nie Qiang , Jiang Benyuan , Zhong Wenzhao , Chen Chun , Li Hecheng 
Published: October 2022

ObjectiveAnatomical segmentectomy has been proven to be a viable surgical treatment for small-size peripheral lung nodules. Three-dimensional (3D) reconstruction computed tomography (CT) has been proposed as an effective approach to overcome the challenges of encountering pulmonary anatomical variations when performing segmentectomy. Therefore, to further investigate the usefulness of preoperative 3D reconstruction CT in segmentectomy, we will conduct this prospective, multicenter randomized controlled DRIVATS study to compare the use of 3D reconstruction CT with standard chest CT in video-assisted segmentectomy (ClinicalTrials.gov ID: NCT04004494).MethodsThis study began in July 2019 and a total of 190 patients will be accrued from three clinical centers within 4 years. The main inclusion criteria are patients with a single peripheral nodule 0.8–2 cm with at least one of the following requirements: (i) histology of adenocarcinoma in situ; (ii) nodule has ≥50% ground-glass appearance on CT; (iii) radiologic surveillance confirms a long doubling time (≥400 days). Surgical procedures include segmental resection of the lesion and mediastinal lymph node sampling (subsegmental resection or combined subsegmental resection will not be included in this study). The primary endpoint is operative time. The secondary endpoints include incidence of change of surgical plan, intraoperative blood loss, conversion rate, operative accident event, incidence of postoperative complications, postoperative hospital stay, length of hospitalization, duration of chest tube placement, postoperative 30-day mortality, dissection of lymph nodes, overall survival, disease-free survival, preoperative lung function, and postoperative lung function.DiscussionThis multicenter DRIVATS study aims to verify the usefulness of preoperative 3D reconstruction CT compared with standard chest CT in segmentectomy. If successfully completed, this multicenter prospective study will provide a higher level of evidence for the use of 3D reconstruction CT in segmentectomy.
Correlation between component alignment and short-term clinical outcomes after total knee arthroplasty
Authors: Luan Yichao , Zhang Min , Ran Tianfei , Wang Huizhi , Fang Chaohua , Nie Maodan , Wang Min , Cheng Cheng-Kung 
Published: October 2022

ObjectiveThis study aimed to investigate the correlation between component alignment and short-term clinical outcomes after total knee arthroplasty (TKA).Methods50 TKA patients from a regional hospital were enrolled in the study. The following component alignments were measured from radiological data acquired within 1 week after surgery: hip-knee-ankle angle (HKA), medial distal femoral angle (MDFA), medial proximal tibial angle (MPTA), femoral flexion-extension angle (FEA), tibial slope angle (TSA), femoral rotational angle (FRA) and tibial rotational angle (TRA). The Hospital for Special Surgery (HSS) knee scoring system was used to assess clinical outcomes after 1 year, with patients being divided into three groups (excellent, good and not good) according to the HSS scores. Difference analysis and linear correlation analysis were used for the statistical analysis.ResultsThe results showed significant differences in MDFA (p = 0.050) and FEA (p = 0.001) among the three patient groups. It was also found that the total HSS had only a moderate correlation with FEA (r = 0.572, p &lt; 0.001), but FEA had a positive linear correlation with pain scores (r = 0.347, p = 0.013), function scores (r = 0.535, p = 0.000), ROM scores (r = 0.368, p = 0.009), muscle scores (r = 0.354, p = 0.012) and stability scores (r = 0.312, p = 0.028). A larger MDFA was associated with lower FE deformity scores (r = −0.289, p = 0.042) and the TSA had a positive influence on the ROM (r = 0.436, p = 0.002). Also, changes in FRA produced a consequent change in the FE deformity score (r = 0.312, p = 0.027), and the muscle strength scores increased as TRA increased (r = 0.402, p = 0.004).ConclusionThe results show that the FEA plays a significant role in clinical outcomes after TKA. Surgical techniques and tools may need to be improved to accurately adjust the FEA to improve joint functionality and patient satisfaction.
Comparison of thoracic ultrasonography and thoracic radiography between healthy adult horses and horses with bacterial pneumonia using a novel, objective ultrasonographic scoring system
Authors: Hepworth-Warren Kate L. , Nelson Nathan , Dembek Katarzyna A. , Young Kimberly A. S. 
Published: October 2022

BackgroundThoracic ultrasonography (TUS) is widely used in equine practice but comparison to radiography is limited in horses.ObjectivesTo validate a novel, objective scoring system for TUS in adult horses and to compare ultrasonographic and radiographic findings.Animals13 healthy horses and 9 with confirmed bacterial pneumoniaMethodsProspective study in which TUS and radiography were performed on healthy horses and those with bacterial pneumonia confirmed by clinical signs and results of transtracheal wash analysis. Ultrasonography was scored utilizing a novel scoring system evaluating number of comet tail lesions, the presence or absence of pleural effusion and/or pulmonary consolidation in each intercostal space. Eighteen horses had thoracic radiographs taken that were scored by a board-certified radiologist utilizing a previously described system. Total scores were recorded and compared between control and diseased patients.Results/FindingsUltrasonographic scores were significantly higher in the diseased group (median= 126) than in the control group (median = 20, p = 0.01). Receiver operating characteristics (ROC) analysis identified a sensitivity of 66.7% (95% CI 0.417–1) and specificity of 92.3% (95% CI 0.462–1) for the ability of ultrasonography to identify bacterial pneumonia utilizing a TUS score cutoff of 37.Conclusions and clinical importanceTUS had moderate sensitivity and high specificity for identification of bacterial pneumonia in adult horses. TUS appears to be an acceptable stand-alone imaging modality for diagnosis of bacterial pneumonia in horses when radiography is not practical.
On Holomorphic Contractibility of Teichmüller Spaces
Authors: Krushkal Samuel L. 
Published: October 2022

The problem of the holomorphic contractibility of Teichmüller spaces T(0,n) of the punctured spheres (n>4) arose in the 1970s in connection with solving algebraic equations in Banach algebras. Recently it was solved by the author. In the present paper, we give a refined proof of the holomorphic contractibility for all spaces T(0,n), n>4 and provide two independent proofs of holomorphic contractibility for low-dimensional Teichmüller spaces, which has intrinsic interest.
First Isolation of Pseudogymnoascus destructans, the Fungal Causative Agent of White-Nose Syndrome, in Korean Bats (Myotis petax)
Authors: Kim Young-Sik , Yang Myun-Sik , Jeong Chang-Gi , Chung Chul-Un , Oem Jae-Ku 
Published: October 2022

White-nose syndrome (WNS), caused by Pseudogymnoascus destructans (Pd), is a lethal fungal disease that affects hibernating bats in North America. Recently, the presence of Pd was reported in countries neighboring Korea. However, Pd has not been investigated in Korea. Therefore, this study aimed to identify the presence of Pd in Korean bats. Altogether, wings from 241 bats were collected from 13 cities and cultured. A total of 79 fungal colonies were isolated, and two isolates were identified as Pd using polymerase chain reaction. Of the nine bat species captured in 13 cities, Pd was isolated only from Myotis petax in Goryeong. Atypical, curved conidia were observed in two isolated fungal colonies. Although histological lesions were not observed by hematoxylin and eosin or periodic acid–Schiff staining, fungal invasion was observed in the tissue sections. Taken together, these results confirmed the presence of Pd in Korean bats and suggest the possibility of WNS outbreaks in Korean bats. This is the first report of the isolation and molecular analysis of Pd from Korean bats.
Weakened Impacts of the East Asia-Pacific Teleconnection on the Interannual Variability of Summertime Precipitation over South China since the Mid-2000s
Authors: Lu Wei , Zhu Yimin , Zhong Zhong , Hu Yijia , Ha Yao 
Published: October 2022

The current study concentrates on the interdecadal shift in the interannual variability of summertime precipitation (IVSP) over South China (SC). Possible causes for the interdecadal shift are explored. The IVSP on a decadal time scale presents a significant weakening after the mid-2000s. The results show that the variances of the interannual precipitation variability over the SC region between 1993 and 2004 (hereafter S1) and 2005 and 2020 (hereafter S2) are 1.40 mm d−1 and 0.58 mm d−1, respectively. The variance of the IVSP has decreased by 58.6% since the mid-2000s. The current study reveals that the reduction in the IVSP over SC after the mid-2000s is prominently attributed to the weakened impact of the East Asia-Pacific (EAP) teleconnection. Before the mid-2000s, the interannual variation of the east-west movement of the western Pacific subtropical high was more significant. The warming over the tropical central-eastern Pacific (CEP) and cooling over the western Pacific (WP) suppress the Walker cell in the tropical Pacific and induce anomalous Hadley cell with its descending branch over the WP in the wet years. The anomalies of SST and atmospheric circulation show opposite phases in the dry years. This SSTA pattern enhances the northward propagation of the EAP teleconnection through a Rossby-wave-type response, which triggers an ascending/descending branch with active/suppressed convection over the northwestern Pacific in the wet/dry years. Therefore, the cooling WP and El Niño in its developing phase provide an ideal condition for more precipitation over SC. However, the above ocean–atmosphere interactions changed after the mid-2000s. The significant SST changes in the tropical CEP and the WP weaken the EAP teleconnection and atmospheric circulation anomalies over SC, leading to a significant interdecadal reduction in the IVSP over SC after the mid-2000s.
محاسبة الموارد البشرية: نحو مقاربة تسييرية لرأس المال البشري -دراسة حالة مديرية الصيانة الأغواط، سوناطراك-
Authors: Abdi Naima 
Published: October 2022

تعرض هذه الورقة مكانة ممارسات محاسبة الموارد البشرية كآلية للتحكم في الاستثمار البشري. حيث تم التأكيد علـى أن العنصر البشري هو العنصر الأكثر أهمية في أي مؤسسة، وأن الاستثـــــمارات الموجهة لزيادة المعرفة؛ مهارات واستعدادات القوى العــــــاملة هي استثمارات في الموارد البشرية. فبعد التعرف على المفاهيم النظرية لمحاسبة الموارد البشريـــــــة وطرق تقييمها ؛ حاولنا دراسة مدى إمكانية تطبيق محاـــــسبة الموارد البشرية بمديرية صيانة الأغواط ، سوناطراك. حيث أظهرت نتائج الدراسة أن محاسبة الموارد البشرية (HRA) ) و بالرغم من أنها تعتمد على أسس موضوعية فهي لا تزال لم تتلقى القبول الكافي؛ حيث تعتمد كفاءتها على عوامل كثيرة ، خاصة البيئة القانونية والتنظيمية والمؤسسية.
The impact of economic recovery programs on indicators of economic welfare in Algeria -An econometric study using the ARDL model for the period 2000-2020-
Authors: Djorfi Zakaria , Mekhnane Okba , Bounehas Adel 
Published: October 2022

In light of the financial surpluses that it achieved as a result of the high oil prices, Algeria proceeded to generalize a long-run strategy through the application of an expansionary policy aimed at reviving investment dynamism in a way that would ensure the revival of macroeconomic indicators and work to raise the absorptive efficiency of the Algerian economy. Therefore, This Study aims to determine the short and long-run relationship between public expenditures and per capita gross domestic product (welfare index), during the period 2000-2020, using the ARDL model. The econometric study concluded that public expenditures have a positive impact on the per capita GDP only in the long run by 55%. In addition to, The estimated model has no econometric problems.
COMPARATIVE EVALUATION OF CARBON SEQUESTRATION ACCOUNTING METHODS BY PINE-BIRCH FOREST PLANTATIONS IN VORONEZH REGION
Authors: Mamonov Dmitry , Morkovina Svetlana , Matveev Sergey , Sheshnitsan Sergey , Ivetić Vladan 
Published: October 2022

Current state of forest carbon budget accounting both in Russia and abroad is characterized by wide variety of
methodological approaches and models. Therefore, final estimates have discrepancies. The results of comparative analysis of methods used to assess carbon sequestration in pine-birch forest stands are presented. The composition, growth
and biological productivity of forest stands were analyzed as well as carbon stock was calculated for pine-birch forest
stands in various age groups in the Central Forest-Steppe. The dynamics of biological productivity of modal forest
stands with mixed composition is investigated. Significant differences were found in quantitative assessment of carbon
deposited by forest stands obtained with three different methodologies. Discrepancies in carbon content estimations in
forest stands with different age and composition obtained by different methods vary from 2.0 to 33.9%. The problem of
reliable assessment of carbon sequestration by forest ecosystems of the Central Forest-Steppe requires regional approaches in development of assessment methods to provide precise results and minimize uncertainty of evaluations
SISTEM PENDATAAN KOLEKTIF MULTI SENSOR SECARA REALTIME BERBASIS ARDUINO
Authors: Luthfiyan Itmamur Roghib , Nurraharjo Eddy , Yulianton Heribertus 
Published: October 2022

Jamur tiram (Pleurotus ostreatus) merupakan komoditas pangan yang sangat diminati masyarakat selain kandungan nutrisinya yang tinggi jamur tiram juga dapat diolah menjadi berbagai ragam makanan, Jamur tiram tumbuh baik pada temperatur 16 - 30°C dan kelembaban relatif 80 – 95%, Intensitas cahaya yang optimum bagi jamur tiram yaitu intensitas cahaya rendah, atau bahkan tanpa adanya cahaya. Akan tetapi, pada saat fase tubuh buah dewasa jamur tiram tidak dapat tumbuh pada kondisi cahaya gelap, melainkan dapat tumbuh dengan optimal pada lingkungan yang agak terang.
Menyikapi masalah diatas maka dari itu penulis ingin mencoba melakukan percobaan penelitian dengan menerapkan pencahayaan dalam ruangan (box) dengan tiga jenis warna lampu yaitu merah (Red), hijau (green) dan biru (blue). dan perlu adanya suatu alat yang dapat melakukan monitoring, serta pendataaan pertumbuhan tanaman jamur tiram yang kemudian akan diambil datasetnya.
Alat monitoring dan pendataan secara realtime dengan menggunakan multi sensor berbasis arduino untuk pendataan pertumbuhan jamur tiram ini dibuat sistem aplikasi android sebagai media untuk pemantauanya, data yang ditampilkan di aplikasi monitoring adalah hasil pembacaan dari beberapa sensor yang dipakai antara lain dari sensor load cell, sensor ultrasonik, serta sensor LDR dan sensor DHT11, Sistem monitoring dan pendataan multi sensor ini juga memiliki fitur untuk melakukan penyimpanan data, hasil data disimpan di penyimpanan internal smartphone, sehingga dari data tersebut dapat digunakan sebagai bahan untuk mengambil keputusan dari obyek yang sedang dimonitoring tersebut.
PENGENALAN GEDUNG BERSEJARAH JIWASRAYA SEMARANG MELALUI MEDIA PEMBELAJARAN BERBASIS AUGMENTED DAN VIRTUAL REALITY
Authors: Februariyanti Herny , Utomo Mardi Siswo , Ningsih Dewi Handayani Untari , Nurraharjo Eddy 
Published: October 2022

Bangunan bersejarah gedung Jiwasraya yang berada di wilayah kota lama Semarang merupakan salah satu bangunan cagar budaya yang dibangun sekitar tahun 1916. Gedung Jiwasraya yang merupakan salah satu gedung peninggalan jaman kolonial yang perlu dilestarikan karena mempunyai nilai sejarah yang tinggi, bentuk arsitektur yang megah dan usia bangunan yang cukup tua.
Adanya kemajuan teknologi sekarang ini memungkinkan bangunan bersejarah yang mempunyai nilai histori yang tinggi dapat dilestarikan dengan menggunakan teknologi augmented reality dan virtual reality. Pelestarian bangunan bersejarah menggunakan teknologi augmented reality dan virtual reality dengan membuat bentuk model bangunan nyata yang mempunyai nilai histori ke dalam bentuk virtual. Teknologi augmented reality dan virtual reality dalam memvisualisasikan bangunan bersejarah dimasukkan dalam sebuah aplikasi mobile.
Aplikasi mobile yang dapat memvisualisasikan bangunan bersejarah khususnya gedung Jiwasraya dalam bentuk augmented reality dan virtual reality akan mempermudah masyarakat dalam mengenal dan melestarikan bangunan berserjarah tersebut. Melalui sentuhan teknologi akan dapat melestarikan bangunan bersejarah sesuai dengan perkembangan jaman. Generasi muda juga akan mudah untuk mengeksplor tentang bangunan bersejarah gedung Jiwasraya menggunakan kemajuan teknologi.
Contested Identities; Competing Accountabilities: The Making of a ‘Good’ Public Schoolteacher in Khyber Pakhtunkhwa, Pakistan
Authors: Siddiqi Soufia A. 
Published: October 2022

This paper investigates norms, practices and contests that shape public school teaching in Khyber Pukhtunkhwa (KP) province, Pakistan and it traces how teacher-bureaucrats are detracted from, and motivated towards, learning-oriented performance.
Pengaruh media edukasi aplikasi “Acenting Seni” terhadap pengetahuan dan sikap cegah stunting sejak dini pada wanita usia subur 20–25 tahun
Authors: Medinawati Dewi Septi , Melani Vitria , Sa’pang Mertien , Harna Harna 
Published: October 2022

Latar Belakang: Stunting termasuk salah satu masalah gizi yang menjadi perhatian tinggi di Indonesia. Stunting menggambarkan kondisi gagalnya pertumbuhan fisik akibat kekurangan gizi saat dalam kandungan hingga usia dua tahun. Stunting dapat dicegah sejak dini, salah satunya dengan meningkatkan pengetahuan dan sikap pada kelompok wanita usia subur (WUS) dalam mempersiapkan kehamilan. Pada era serba digital, edukasi dapat diberikan melalui aplikasi di ponsel pintar. Aplikasi “Acenting Seni” merupakan media edukasi mengenai cegah stunting sejak dini yang dapat diakses melalui Android Playstore. Tujuan: Mengetahui pengaruh edukasi gizi melalui media aplikasi “Acenting Seni” terhadap perubahan pengetahuan dan sikap mengenai cegah stunting sejak dini pada WUS usia 20–25 tahun. Metode: Penelitian ini adalah quasi eksperimen dengan desain one group pre–posttest tanpa kelompok kontrol. Subjek penelitian dipilih menggunakan teknik purposive sampling yang terdiri dari WUS usia 20–25 tahun sebanyak 30 orang. Penelitian dilakukan pada bulan Juli 2021 di enam kecamatan di Kota Palembang. Pengukuran data pengetahuan dan sikap WUS mengenai stunting dikumpulkan menggunakan kuesioner. Intervensi diberikan sebanyak satu kali setelah pretest dengan memberikan edukasi gizi media “Acenting Seni” dibantu penjelasan peneliti mengenai isi materi dari media “Acenting Seni”. Analisis data diolah menggunakan Paired Sample T-test dan Wilcoxon Rank Sum test dengan tingkat signifikasi 5% (p<0,05). Hasil: Setelah pemberian edukasi, terdapat peningkatan skor posttest pengetahuan sebesar 24,5 poin (p=0,0001) dan skor posttest sikap sebesar 20 poin (p=0,0001). Kesimpulan: Media “Acenting Seni” mampu meningkatkan pengetahuan dan sikap responden mengenai cegah stunting sejak dini.