bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative experimental and modelling study of the thermal and thermo-mechanical properties of LLDPE/wax blends
Authors: Mosoabisane Mafereka F. T. , Luyt Adriaan S. , van Sittert Cornelia G. C. E. 
Published: June 2022

AbstractThe interactions and morphology of molecules in a polymer blend influence the physical properties of the blend. However, little is known about the influence of molecular interaction and morphology on the thermal and mechanical properties of LLDPE/wax blends. Although cooling rate can be used to investigate blends' thermal and mechanical properties, it is inadequate to determine interactions between the molecules in the LLDPE/wax blends. However, since the morphology is related to the thermal and mechanical properties of polymer blends and could be related to the cooling rate, LLDPE/wax samples prepared by melt mixing were cooled at different rates. The thermal and mechanical properties of the LLDPE/wax blends were modelled through molecular dynamic simulations. The modelled transitions were compared to experimentally determined mechanical relaxations of LLDPE/wax blends to investigate the effect of wax addition on the blend crystallinity. The crystallization behaviour of the blends was studied by differential scanning calorimetry, dynamic mechanical behaviour by dynamic mechanical analysis, and differences in crystallinity by X-ray diffraction. There were no significant differences between the results for the slow- and quench-cooled samples, confirming the rapid crystallization of both the LLDPE and the wax. Experiments and molecular dynamics simulations confirmed the cocrystallization of wax with LLDPE.
Event detection in surveillance videos: a review
Authors: Karbalaie Abdolamir , Abtahi Farhad , Sjöström Mårten 
Published: June 2022

AbstractSince 2008, a variety of systems have been designed to detect events in security cameras. There are also more than a hundred journal articles and conference papers published in this field. However, no survey has focused on recognizing events in the surveillance system. Thus, motivated us to provide a comprehensive review of the different developed event detection systems. We start our discussion with the pioneering methods that used the TRECVid-SED dataset and then developed methods using VIRAT dataset in TRECVid evaluation. To better understand the designed systems, we describe the components of each method and the modifications of the existing method separately. We have outlined the significant challenges related to untrimmed security video action detection. Suitable metrics are also presented for assessing the performance of the proposed models. Our study indicated that the majority of researchers classified events into two groups on the basis of the number of participants and the duration of the event for the TRECVid-SED Dataset. Depending on the group of events, one or more models to identify all the events were used. For the VIRAT dataset, object detection models to localize the first stage activities were used throughout the work. Except one study, a 3D convolutional neural network (3D-CNN) to extract Spatio-temporal features or classifying different activities were used. From the review that has been carried, it is possible to conclude that developing an automatic surveillance event detection system requires three factors: accurate and fast object detection in the first stage to localize the activities, and classification model to draw some conclusion from the input values.
Barrier Lyapunov function-based fixed-time FTC for high-order nonlinear systems with predefined tracking accuracy
Authors: Wang Xiaolin , Xu Jihui , Lv Maolong , Zhang Lei , Zhao Zilong 
Published: June 2022

AbstractThis article proposes a fixed-time adaptive fault-tolerant control methodology for a larger class of high-order (powers are positive odd integers) nonlinear systems subject to asymmetric time-varying state constraints and actuator faults. In contrast with the state-of-the-art control methodologies, the distinguishing features of this study lie in that: (a) high-order asymmetric time-varying tan-type barrier Lyapunov function (BLF) is devised such that the state variables can be convergent to the preassigned compact sets all the time provided their initial values remain therein, which not only preserves the constraints satisfaction, but warrants the validity of the adopted neural network approximator; (b) the proposed control design ensures the tracking errors converge to specified residual sets within fixed time and makes the size of the convergence regions of tracking errors adjustable a priori by means of a new BLF-based tuning function and a projection operator; (c) a variable-separable lemma is delicately embedded into the control design to extract the control terms in a “linear-like” fashion which not only overcomes the difficulty that virtual control signals appear in a non-affine manner, but also solves the problem of actuator faults. Comparative simulations results finally validate the effectiveness of the proposed scheme.
Teachers’ professional knowledge for teaching early literacy: conceptualization, measurement, and validation
Authors: König Johannes , Hanke Petra , Glutsch Nina , Jäger-Biela Daniela , Pohl Thorsten , Becker-Mrotzek Michael , Schabmann Alfred , Waschewski Tina 
Published: June 2022

AbstractThis study suggests a comprehensive conceptualization of teacher knowledge for teaching early literacy in primary schools. Following the discourse on the professional knowledge of teachers, we argue that teachers’ knowledge relevant to support reading and writing at the beginning of primary school education is multidimensional by nature: Teachers need content knowledge (CK), pedagogical content knowledge (PCK), and general pedagogical knowledge (GPK). Although research on teacher knowledge has made remarkable progress over the last decade, and in particular in domains such as mathematics, relevant empirical research using standardized assessment that would allow in-depth analyses of how teacher knowledge is acquired by pre-service teachers during teacher education and how teacher knowledge influences instructional quality and student learning in early literacy is very scarce. The following research questions are focused on: (1) Can teachers’ professional knowledge for teaching early literacy be conceptualized in terms of CK, PCK, and GPK allowing empirical measurement? (2) How do teachers acquire such knowledge during initial teacher education? (3) Is teachers’ professional knowledge a premise for instructional quality in teaching early literacy to students? We present the conceptualization of teacher knowledge for teaching early literacy in primary schools in Germany as the country of our study and specific measurement instruments recently developed by our research group. Assessment data of 386 pre-service teachers at different teacher education stages is used to analyze our research questions. Findings show (1) construct validity of the standardized tests related to the hypothesized structure, (2) curricular validity related to teacher education, and (3) predictive validity related to instructional quality. Implications for teacher education and the professional development of teachers are discussed.
Against commitment
Authors: Venkatesh Nikhil 
Published: June 2022

AbstractIn his famous ‘Integrity Objection’, Bernard Williams condemns utilitarianism for requiring us to regard our projects as dispensable, and thus precluding us from being properly committed to them. In this paper, I argue against commitment as Williams defines it, drawing upon insights from the socialist tradition as well as mainstream analytic moral philosophy. I show that given the mutual interdependence of individuals (a phenomenon emphasised by socialists) several appealing non-utilitarian moral principles also require us to regard our projects as dispensable. This means that those who endorse those principles cannot appeal to Williams’s argument against utilitarianism. It also puts pressure on his thought that moral theories ought to permit commitment – in fact, it suggests that they ought not.Regarding one’s projects as dispensable may be alienating, and this may motivate us to hang onto commitment and reject these non-utilitarian principles along with utilitarianism. However, commitment also threatens a kind of alienation – from other people. Drawing upon the socialist tradition again, I argue that avoiding this form of alienation is necessary for proper engagement with our projects, and thereby with ourselves.
Development of mechanical soil stability in an initial homogeneous loam and sand planted with two maize (Zea mays L.) genotypes with contrasting root hair attributes under in-situ field conditions
Authors: Rosskopf U. , Uteau D. , Peth S. 
Published: June 2022

Abstract
Purpose
Soil structure evolving from physical and biological processes is closely related to soil mechanical characteristics and texture. We studied the influence of substrate and genotype on the initial development of mechanical traits, differences between depths, and changes over the course of two years in the field.

Methods
Plots were homogeneously filled with a loam and a sand and planted with two maize (Zea mays L.) genotypes (wild type (WT) and rth3 mutant) with contrasting root hair attributes. Undisturbed soil cores were taken in 2019 and 2020 at 14 and 34 cm depth. Confined uniaxial compression tests were performed to determine pre-compression stress (σpc), compressibility (Cc, Cs) and elasticity index (EI). Mechanical energy was calculated based on penetration resistance (PR) tests with a penetrometer needle resembling root geometries.

Results
σpc, Cc and Cs were significantly higher in loam as compared to sand, whereas the factor genotype proved to be negligible. Over time, σpc increased and Cc decreased in loam from 2019 to 2020 and Cs declined in both substrates. Higher mechanical energies were observed in loam and partially in WT. Required energy was higher at 14 cm than at 34 cm depth and decreased from 2019 to 2020 in sand. Airdry sand samples required four times as much energy than those at matric potential (Ψm) of -50 kPa.

Conclusion
For the development of the mechanical traits examined texture proved to be the dominating factor and changes in soil stability could be observed within a short period of time.
Affectivism about intuitions
Authors: Loev Slawa 
Published: June 2022

AbstractThis article provides an account of intuitions: Affectivism. Affectivism states that intuitions are emotional experiences. The article proceeds as follows: first, the features that intuitions are typically taken to have are introduced. Then some issues with extant theories are outlined. After that, emotional experiences and their central features are brought into view. This is followed by a comparison of intuitions and emotional experiences, yielding the result that emotional experiences fit and elucidate the feature profile of intuitions. Finally, it is specified what kind of emotional experiences intuitions are: intuitions are typically mild emotional experiences that belong to the subclass of epistemic feelings.
Changes in the resilience of resprouting juvenile tree populations in temperate forests due to coupled severe drought and fire
Authors: Bendall E. R. , Bedward M. , Boer M. , Clarke H. , Collins L. , Leigh A. , Bradstock R. A. 
Published: June 2022

AbstractElevated tree mortality and reduced recruitment of new trees linked to drought and fires has been reported across a range of forests over the last few decades. Forests that resprout new foliage epicormically from buds beneath the bark are considered highly resilient to disturbance, but are potentially at risk of elevated mortality, demographic shifts and changes to species composition due to synergistic effects of drought and fire. Despite this, the effects of drought-fire interactions on such forests remain largely unknown. We assessed the effects of drought severity and fire frequency on juvenile mortality, post-fire seedling recruitment and replacement of juvenile trees (balance of recruitment minus mortality) following fire. We compared dry ridgetops and wet gullies (i.e. two forest types that inhabit different topographic positions in the landscape) across a temperate forest in southern Australia. Both forest types experienced higher rates of fire-induced juvenile mortality in areas that had experienced severe drought compared to moderate drought, though mortality rates were generally low across all drought and fire combinations (e.g. < 15%). This result indicated that topographic position did little to reduce juvenile mortality when exposed to severe drought plus fire. In wet forest, severe drought also reduced recruitment and replacement of dead juveniles by post-fire seedlings compared to moderate drought. In dry forest net-negative replacement increased with the severity of drought. Across both forest types, the total pool of juveniles was reduced under severe drought (by 16–79 in DSF; 5–11 in WSF). Future increases in the frequency of coupled severe drought and fire could potentially increase the susceptibility of resilient temperate forests to major changes in structure and function.
The impact of patient preference in the treatment algorithm for recurrent/metastatic head and neck squamous cell carcinoma
Authors: Salvestrini Viola , Becherini Carlotta , Desideri Isacco , Caprara Luisa , Mariotti Matteo , Banini Marco , Pierossi Nicola , Scotti Vieri , Livi Lorenzo , Bonomo Pierluigi 
Published: June 2022

AbstractThe advent of immune checkpoint inhibitors for recurrent/metastatic head and neck squamous cell carcinoma (RM-HNSCC) has revolutionized the standard of care approach in first-line treatment. The heterogeneity of disease presentation and treatment-related toxicities can be associated with suboptimal patient compliance to oncologic care. Hence, prioritizing quality of life and well-being are crucial aspects to be considered in tailoring the best treatment choice. The aim of our work is to present a short report on the topic of the patient’s preference in regard to treatment and its consequences on quality of life in the recurrent/metastatic setting. According to the literature, there’s an unmet need on how to assess patient attitude in respect to the choice of treatment. In view of the availability of different therapeutic strategies in first-line management of RM-HNSCC, increasing emphasis should be put on integrating patient preferences into the medical decision-making.
Cardiovascular Damage in COVID-19: What We Know Two Years Later
Authors: Nuzzi Vincenzo , Del Mestre Eva , Degrassi Alessia , Bromage Daniel I. , Manca Paolo , Piper Susan , Artico Jessica , Gentile Piero , Scott Paul A. , Chiatto Mario , Merlo Marco , Pareek Nilesh , Giacca Mauro , Sinagra Gianfranco , McDonagh Theresa A. , Cannata Antonio 
Published: June 2022

Abstract
Purpose of the Review
The Coronavirus disease 2019 (COVID-19) pandemic has profoundly influenced cardiological clinical and basic research in the past two years. In the present review, we summarize the current knowledge on myocardial involvement in COVID-19, providing an overview on the incidence, the pathogenetic mechanisms, and the clinical implications of cardiac injury in this setting.

Recent Findings
The possibility of heart involvement in patients with COVID-19 has received great attention since the beginning of the pandemic. After more than two years, several steps have been taken in understanding the mechanisms and the incidence of cardiac injury during COVID-19 infection. Similarly, studies globally have clarified the implications of co-existing heart disease and COVID-19.

Summary
Severe COVID-19 infection may be complicated by myocardial injury. To date, a direct damage from the virus has not been demonstrated. The presence of myocardial injury should be systematically assessed for a prognostication purpose and for possible therapeutic implications.
Somatostatin receptor-directed molecular imaging for therapeutic decision-making in patients with medullary thyroid carcinoma
Authors: Serfling Sebastian E. , Zhi Yingjun , Megerle Felix , Fassnacht Martin , Buck Andreas K. , Lapa Constantin , Werner Rudolf A. 
Published: June 2022

Abstract
Background
Somatostatin receptor (SSTR) positron emission tomography/computed tomography (PET/CT) is increasingly deployed in the diagnostic algorithm of patients affected with medullary thyroid carcinoma (MTC). We aimed to assess the role of SSTR-PET/CT for therapeutic decision making upon restaging.

Methods
23 pretreated MTC patients underwent SSTR-PET/CT and were discussed in our interdisciplinary tumor board. Treatment plans were initiated based on scan results. By comparing the therapeutic regimen before and after the scan, we assessed the impact of molecular imaging on therapy decision. SSTR-PET was also compared to CT portion of the SSTR-PET/CT (as part of hybrid imaging).

Results
SSTR-PET/CT was superior in 9/23 (39.1%) subjects when compared to conventional CT and equivalent in 14/23 (60.9%). Those findings were further corroborated on a lesion-based level with 27/73 (37%) metastases identified only by functional imaging (equivalent to CT in the remaining 46/73 (63%)). Investigating therapeutic decision making, no change in treatment was initiated after PET/CT in 7/23 (30.4%) patients (tyrosine kinase inhibitor (TKI), 4/7 (57.2%); surveillance, 3/7 (42.8%)). Imaging altered therapy in the remaining 16/23 (69.6%). Treatment prior to PET/CT included surgery in 6/16 (37.5%) cases, followed by TKI in 4/16 (25%), active surveillance in 4/16 (25%), and radiation therapy (RTx) in 2/16 (12.5%) subjects. After SSTR-PET/CT, the therapeutic regimen was changed as follows: In the surgery group, 4/6 (66.7%) patients underwent additional surgery, and 1/6 (16.7%) underwent surveillance and TKI, respectively. In the TKI group, 3/4 (75%) individuals received another TKI and the remaining subject (1/4, 25%) underwent peptide receptor radionuclide therapy. In the surveillance group, 3/4 (75%) underwent surgery (1/4, (25%), RTx). In the RTx group, one patient was switched to TKI and another individual was actively monitored (1/2, 50%, respectively). Moreover, in the 16 patients in whom treatment was changed by molecular imaging, control disease rate was achieved in 12/16 (75%) during follow-up.

Conclusions
In patients with MTC, SSTR-PET/CT was superior to CT alone and provided relevant support in therapeutic decision-making in more than two thirds of cases, with most patients being switched to surgical interventions or systemic treatment with TKI. As such, SSTR-PET/CT can guide the referring treating physician towards disease-directed treatment in various clinical scenarios.
Glycosylation and its research progress in endometrial cancer
Authors: Pu Congli , Biyuan  , Xu Kai , Zhao Yingchao 
Published: June 2022

AbstractEndometrial cancer (EC) is one of the most common tumors in the female reproductive system, which seriously threatens women's health, particularly in developed countries. 13% of the patients with EC have a poor prognosis due to recurrence and metastasis. Therefore, identifying good predictive biomarkers and therapeutic targets is critical to enable the early detection of metastasis and improve the prognosis. For decades, extensive studies had focused on glycans and glycoproteins in the progression of cancer. The types of glycans that are covalently attached to the polypeptide backbone, usually via nitrogen or oxygen linkages, are known as N‑glycans or O‑glycans, respectively. The degree of protein glycosylation and the aberrant changes in the carbohydrate structures have been implicated in the extent of tumorigenesis and reported to play a critical role in regulating tumor invasion, metabolism, and immunity. This review summarizes the essential biological role of glycosylation in EC, with a focus on the recent advances in glycomics and glycosylation markers, highlighting their implications in the diagnosis and treatment of EC.
Gloomy and out of control? Consequences of the COVID-19 pandemic on momentary optimism in daily lives of adolescents
Authors: Wieczorek Larissa L. , Bleckmann Eva , Brandt Naemi D. , Wagner Jenny 
Published: June 2022

Abstract
In the global COVID-19 pandemic, adolescents are regarded as especially burdened due to school closures and leisure activities being banned, often reducing peer contacts to zero. Experiencing restrictions while being uninvolved in decision-making processes left them with little control over their daily lives. Meanwhile, research highlights that optimism can act as a buffer against the impact of daily hassles and is considered an important resource for mental health. To understand the implications of the COVID-19 pandemic for adolescents' lives, this study examined how momentary perceived control and perceived personal and societal consequences of the COVID-19 pandemic relate to momentary optimism. Using experience-sampling data from N = 242 (Mage = 15.89; 86% female) adolescents assessed during the second pandemic wave in Germany, multilevel modeling revealed positive associations between adolescents’ momentary perceived control and their momentary optimism at both the within- and between-person level. Additionally, perceived consequences of the COVID-19 pandemic showed specific associations with momentary optimism: Whereas perceived societal consequences were directly related to lower momentary optimism, perceived personal consequences strengthened the relationship between momentary perceived control and optimism. These findings highlight the role of perceived control as an important resource for optimism both as a general tendency and within specific situations in daily life. This way, our results may shed light on how to support adolescent optimism during states of emergency, such as a worldwide pandemic.
Localised solid-state nanopore fabrication via controlled breakdown using on-chip electrodes
Authors: Fried Jasper P. , Swett Jacob L. , Nadappuram Binoy Paulose , Fedosyuk Aleksandra , Gee Alex , Dyck Ondrej E. , Yates James R. , Ivanov Aleksandar P. , Edel Joshua B. , Mol Jan A. 
Published: June 2022

AbstractControlled breakdown has recently emerged as a highly accessible technique to fabricate solid-state nanopores. However, in its most common form, controlled breakdown creates a single nanopore at an arbitrary location in the membrane. Here, we introduce a new strategy whereby breakdown is performed by applying the electric field between an on-chip electrode and an electrolyte solution in contact with the opposite side of the membrane. We demonstrate two advantages of this method. First, we can independently fabricate multiple nanopores at given positions in the membrane by localising the applied field to the electrode. Second, we can create nanopores that are self-aligned with complementary nanoelectrodes by applying voltages to the on-chip electrodes to locally heat the membrane during controlled breakdown. This new controlled breakdown method provides a path towards the affordable, rapid, and automatable fabrication of arrays of nanopores self-aligned with complementary on-chip nanostructures.