bluuebunny/crossref_metadata_2025_split huggingface dataset:
On Covid-19 and mental health
Authors: El Haj Mohamad , Boutoleau-Bretonnière Claire , Allain Philippe , Kapogiannis Dimitrios , Chapelet Guillaume , Gallouj Karim 
Published: May 2022

Abstract
While visiting and socialization restrictions during lockdowns were instituted to cope with the Covid-19 spread and to prolong the life of residents of retirement homes, these measures could have been expected to decrease the quality of life of their residents.
We assessed longitudinal effects of the two successive lockdowns, as implemented in France, on mental health (i.e., depression, anxiety, and loneliness) in 62 retirement home residents with Alzheimer disease (AD).
Analysis demonstrated higher levels of depression, anxiety, and loneliness during the second lockdown than during the first lockdown.
The increased levels of depression, anxiety, and loneliness during the second lockdown can be attributed to the longer duration of the restrictive measures, especially the restriction of visits, that were implemented in retirement homes. In addition, the increased workload of geriatric healthcare workers leading to higher levels of burnout and decreased quality of care may help explain the increased loneliness, depression, and anxiety of retirement home residents with AD, which were observed during the second Covid-19 era lockdown.
The effect of 0.01% atropine and orthokeratology on ocular axial elongation for myopia children
Authors: Yu Yan , Liu Jiasu 
Published: May 2022

Abstract

Objectives
This meta-analysis aimed to identify the therapeutic effect of 0.01% atropine with orthokeratology on ocular axial elongation for myopia children.

Methods
We searched PubMed, Cochrane Library, and CBM databases from inception to July 1st, 2021. Meta-analysis was conducted using STATA version 14.0 and Review Manager version 5.3 softwares. We calculated the weighted mean differences to analyze the change of ocular axial length (AL) between orthokeratology combined with 0.01% atropine (OKA) and) alone. The Cochran's Q-statistic and I
2 test were used to evaluate potential heterogeneity between studies. To evaluate the influence of single studies on the overall estimate, a sensitivity analysis was performed. We also performed sub group and meta-regression analyses to investigate potential sources of heterogeneity. We conducted Begger funnel plots and Egger linear regression tests to investigate publication bias.

Results
Nine studies that met all inclusion criteria were included in this meta-analysis. A total of 191 children in OKA group and 196 children in orthokeratology (OK) group were assessed. The pooled summary weighted mean differences of AL change was -0.90 (95% CI = −1.25−0.55) with statistical significance (t = −5.03, P < .01), which indicated there was obvious difference between OKA and OK in myopic children. Subgroup analysis also showed that OKA treatment resulted in significantly less axial elongation compared to OK treatment alone according to SER. We found no evidence for publication bias.

Conclusions
Our meta-analysis indicates 0.01% atropine atropine is effective in slowing axial elongation in myopia children with orthokeratology.
Zhengqing fengtongning sustained-release tablets prevents gout flares in the process of ULT
Authors: Jia Ertao , Hu Shasha , Geng Hongling , Zhu Haiqiong , Xie Jingjing , Xiao Yuya , Jiang Yubao , Xiao Min , Zhang Jianyong 
Published: May 2022

Abstract

Introduction:
When initiating urate-lowering therapy, using anti-inflammatory prophylaxis therapy for at least 3 to 6 months is strongly recommended. Previous studies have found that zhengqing fengtongning sustained-release tablets (sinomenine) can improve inflammation in the acute phase of gout; however, the efficacy of urate-lowering therapy in reducing frequency of acute flares still needs to be investigated. The aim of the present study is to explore the efficacy and safety of sinomenine for prophylaxis of acute flares when initiating urate-lowering therapy.

Methods and analysis:
This randomized, placebo-controlled, double-blinded trial will include a total of 210 gout patients who meet the study criteria. The patients will be randomized (1:1) to the test group and the control group. The intervention is planned to be performed for 12 weeks with a follow-up of 12 weeks. All patients would be administered febuxostat (40 mg/d) and concomitant anti-inflammatory prophylaxis therapy. Sinomenine and colchicine placebo are administered in the sinomenine group, sinomenine placebo and colchicine are administered in the colchicine group. The primary outcome is the rate of acute gout flares in subjects within 12 weeks of the treatment period. The secondary outcomes include the times of acute gout flares and the duration of each acute flares within 12 weeks; the compliance rate in patients whose UA levels ≤6.0 mg/dL (360 μmol/L) at the weekend of 2nd, 4th, 8th, and 12th week in each group; the proportion of patients with ≥1 and ≥2 gout flares within 12 weeks; average visual analogue scale/score pain score during gout flares; and the oral dose of etoricoxib will be used to control the onset of acute flares within 12 weeks.

Ethics and dissemination:
The Institutional Medical Ethics Committee have approved the trial protocol. We plan to publish the results of this study in a peer-reviewed journal.

Trial registration:
ChiCTR, ChiCTR2100045114, Registered 8 April 2021 http://www.chictr.org.cn/showproj.aspx?proj=124688
Primary salivary gland-type polymorphous adenocarcinoma in the lung
Authors: Xu Hong-Bo , Yang Mai-Qing , Wang Jing-Ru , Qi Hong-Feng , Lin Xu-Yong , Zhang Hai-Ning , Xu Hong-Tao 
Published: May 2022

Abstract

Rationale:
Polymorphous low-grade adenocarcinoma is a low-risk infiltrative malignant tumor of the salivary glands. However, some of these tumors are more malignant than the low-grade tumors and therefore, according to the most recent recommendation of the World Health Organization, they are renamed as polymorphous adenocarcinomas (PACs). Primary polymorphous low-grade adenocarcinomas/PACs of the lungs are rare. Herein, we report a case of primary PAC of the lung with bronchial cartilage and perineural invasion, and lymph node metastasis.

Patient concerns:
A 58-year-old man had developed fever half a month prior, without chills or other accompanying symptoms, and the underlying reasons were unknown. His self-measured temperature was up to 39°C, accompanied by cough and expectoration, yellow and thin sputum, and shortness of breath. The patient's general state was normal, and respiratory sounds originating from the right lung were weak. Enhancement computed tomography revealed that the bronchial lumen of the basal segment of the lower lobe of the right lung was narrow; soft tissue density nodules were seen, with a range of approximately 2.4 cm × 1.3 cm.

Diagnosis:
Based on clinical information, morphological features, and immunohistochemistry results, the pathological diagnosis was primary PAC of the lungs.

Intervention:
Thoracoscopic resection of the middle and lower lobes of the right lung was performed, further extended dissection of the mediastinal lymph nodes was performed.

Outcomes:
The postoperative course was uneventful.

Lessons:
Primary PAC of the lung is rare and may cause misdiagnosis. When encountering a lung tumor with diverse tissue structures, uniform cell type and nerve invasion, we should consider the possibility of PAC. Morphological and immunohistochemical features can be useful for diagnosing primary PAC of the lungs.
The 68Ga-DOTA-FAPI-04 PET/CT for the differential diagnosis of solitary fibroma of pleura from other chest disease with low uptake of 18F-FDG
Authors: Zhang Annan , Meng Xiangxi , Zhou Xin , Wang Shuailiang , Zhang Yan , Li Nan 
Published: May 2022

Objective
We conducted a prospective study using 68Ga-DOTA-FAPI-04 PET/computed tomography (CT) to differentiate solitary fibromas of pleura (SFP) from other chest similar masses showing low uptake of 18F-FDG.

Methods
A prospective study including 13 patients was divided into two groups: five cases of SFP and eight of thoracic lesions resembling SFP on general imaging examination. Except for CT and MRI, all patients underwent both 18F-FDG and 68Ga-DOTA-FAPI-04 PET/CT examinations. Compare the differences of lesions in CT net enhancement value and the uptake of 18F-FDG and 68Ga-DOTA-FAPI-04 between the two groups. The values of CT and PET/CT for differential diagnosis were calculated by receiver operating characteristic (ROC) curves.

Results
The uptake of 68Ga-DOTA-FAPI-04 in SFP was significantly higher than the others in chest, SUVmean (8.10 ± 5.57) versus (1.11 ± 0.38); and SUVmax (15.46 ± 8.16) versus (3.96 ± 2.43), and the difference was statistically significant (P < 0.05). The 68Ga-DOTA-FAPI-04 could effectively distinguish SFP from other lesions, and the accuracies of SUVmax and SUVmean for differential diagnosis were 92.31 and 100%, the corresponding cutoff value being 7.19 and 2.26. The uptake of 18F-FDG in SFP was slightly lower than other lesions, SUVmean (1.63 ± 0.30) versus (1.88 ± 1.02); and SUVmax (2.51 ± 0.54) versus (3.60 ± 1.57), and the difference was not statistically significant (P > 0.05). The SFP showed significant enhancement in the venous phase, but the difference was not statistically significant (P > 0.05).

Conclusion
The 68Ga-DOTA-FAPI-04 has potential application value in differentiating SFP from lesions with low 18F-FDG uptake, in addition, 68Ga-DOTA-FAPI-04 may specifically target SFP.
Factors affecting learners’ perception of e-learning during the COVID-19 pandemic
Authors: Perera R.H.A.T. , Abeysekera Nalin 
Published: May 2022

PurposeThe purpose of this paper is to identify the factors affecting learners' perception of e-learning during the Coronavirus-2019 (Covid-19) pandemic. Furthermore, it investigates mechanisms that enhance students' engagement in e-learning, especially under the constraints created by the pandemic.Design/methodology/approachQuantitative research approach was used, and data were collected using a structured questionnaire. The sample consisted of 163 undergraduates registered at the Faculty of Management Studies of the Open University of Sri Lanka (OUSL). The structured questionnaire was designed taking into consideration learners attached to different regional centers and study centers of the OUSL.FindingsAs per the findings, performance expectancy, social influence, effort expectancy and service quality are the factors which have significant effects on students' “intention to use” e-learning as a method of pursuing education. Furthermore, it was observed that 65.6% of the students had access to technology through mobile phones, while 53.4% of the students had engaged in e-learning for the first time. This was mainly due to restrictions that were imposed during the Covid-19 pandemic.Practical implicationsThe study will help in formulating policies and introducing procedures in relation to online teaching-learning models to be used by both teachers and learners, especially in similar pandemic situations in the future.Originality/valueThis study will assist to determine the effectiveness of the e-learning system used by the OUSL. The findings highlighted the importance of improving information technology (IT) facilities available at all the regional and study centers across Sri Lanka.
Performance of small businesses in Tangier: the perceptual role of location
Authors: Sefiani Yassine , Davies Barry , Bown Robin 
Published: May 2022

PurposeThis study seeks to investigate perceptions of the role of location on the performance of small and medium enterprises (SMEs) in Tangier, as understood by local owner-managers.Design/methodology/approachTo explore perceptions of the performance/location relationship for SMEs in Tangier, 20 in-depth online semi-structured interviews were conducted with selected owner-managers of SMEs. The judgement sample was selected to explore their experiences, beliefs and attitudes with respect to their performance and location.FindingsFindings of the study revealed that “location” is a salient factor that, in the minds of respondents, materially influences the performance of SMEs in Tangier. Location was mentioned extensively in the interviews, in relation to the “free zones”. Findings showed that firms located within the free zones enjoyed favourable economic conditions, in particular those related to taxation and competition, compared to their counterparts located outside the free zones, which were excluded from these benefits. Furthermore, perceived unfair competition (financial and fiscal incentives in the free zones) damages the performance of the SMEs in Tangier. These findings suggest that the placement of the business in relation to the free zones and in respondents' perception thus became an important financial and emotionally significant perspective on equality in relation to success.Research limitations/implicationsThe findings of the study could encourage the government to adopt policies that will assist indigenous firms to benefit from advantages that are comparable to those that are available to those in the free zones. Greater attention to the perceptual effects of location would be advantageous. However, the exploratory nature of the study means that results cannot necessarily be generalised beyond the setting in which the data were collected. Future research should examine the impact of location for SMEs in a broader sample of countries.Originality/valueThis study is among those few studies located in the Middle East North Africa (MENA) region that explore the performance of SMEs from the perceptions of owner-managers themselves and not based on aggregate or economic data. It supports previous findings of several studies and contributes additional evidence that suggests the significance of levelling the playing field and its impact on SME performance in the contemporary African business context.
Thermal performance and indoor air quality in new, medium density houses – Auckland, New Zealand
Authors: Birchmore Roger Clive , Berry Terri-Ann , Wallis Shannon L. , Tsai Steve , Hernandez German 
Published: May 2022

PurposeNew Zealand’s historical housing stock comprises largely single-storey detached houses, characterised by poor winter comfort with high air infiltration. Challenges with affordability and land use are shifting New Zealand’s housing stock towards double-storey, conjoined medium-density housing (MDH). Reduced external surfaces in this typology should reduce winter heat loss and infiltration, improving winter comfort and health. New concerns arise, however, regarding summertime overheating and poor indoor air quality.Design/methodology/approachA field study was undertaken where temperature, humidity, airtightness, particulate matter (PM) and total volatile organic compounds (TVOC) were measured in two unoccupied, newly built double-storey, conjoined houses, for several weeks over summer.FindingsThe reduced surface area of this typology did not reduce infiltration and demonstrated significant periods of overheating. Internal PM concentrations generally exceeded outdoor concentrations but did not exceed annual average outdoor PM10 guidelines of 20 µg m-3. Infiltration factors (Finf) were closer to more traditional houses. TVOC readings varied widely, but frequently exceeded international guidelines.Research limitations/implicationsThe small sample limits the applications of conclusions more widely. Recommendations to investigate a wider sample in different locations with more detailed VOC analysis over all seasons are made.Practical implicationsImprovements to internal environments cannot be guaranteed by housing typology changes alone and must still involve thoughtful environmental design.Social implicationsHousing typology changes may not improve internal living environments.Originality/valueA move to the new MDH typology may not achieve expectations of airtightness and thermal improvement. New challenges arise from significant overheating and high TVOC levels, which may lead to new negative health effects.
Landscape planning and design by identifying areas for ecological restoration based on carbon fluxes
Authors: do Amaral Rubens , de Lima Bezerra Maria do Carmo , de Mello Baptista Gustavo Macedo 
Published: May 2022

PurposeHuman actions on natural ecosystems have not only jeopardized human well-being but also threatened the existence of other species. On the other hand, the benefits resulting from a greater integration between the logic of nature and human occupations have been seen as motivating factors for the prevention and mitigation of environmental impacts in landscape planning, since it provides human well-being through the grant of resources, regulation of the environment and socio-cultural services called ecosystem services. This article highlights the relevance of using ecosystem integrity indicators related to the functioning of ecological support processes for landscape planning.Design/methodology/approachThe research used the photosynthetic performance of vegetation through carbon fluxes in the landscape, defining areas where different approaches to green infrastructure can be applied, gaining over the majority of work in this area, in which low degrees of objectivity on measurement and consequent ecological recovery still prevail. Thus, using the conceptual support of restoration ecology and remote sensing, the work identified different vegetation performances in relation to the supporting ecological processes using the multispectral CO2flux index, linked to the carbon flux to identify the photosynthetic effectiveness of the vegetation and the Topographic Wetness Index (TWI).FindingsWith a study in the Distrito Federal (DF), the results of the different performances of vegetation for ecological support, through electromagnetic signatures and associated vegetation formations, allowed for the identification of hotspots of greater integrity that indicate multifunctional areas to be preserved and critical areas that deserve planning actions using green infrastructure techniques for their restoration and integration into the landscape.Originality/valueThis approach could be the initial step towards establishing clear and assertive criteria for selecting areas with greater potential for the development of supporting ecological processes in the territorial mosaic.
Fostering green service innovation perceptions through green entrepreneurial orientation: the roles of employee green creativity and customer involvement
Authors: Luu Tuan Trong 
Published: May 2022

Purpose
Developing new green services is critical to a hospitality organization’s achievement of sustainable goals as well as competitive advantage. This study aims to unravel the mechanisms through which organizations with green entrepreneurial orientation (green EO) can foster green service innovation.

Design/methodology/approach
The data set for testing these mechanisms was garnered from employees and managers who worked in hotels based in an Asia-Pacific market. A multilevel analysis was conducted on this data set.

Findings
The results revealed the positive nexus between organizational green EO and green service innovation perceptions. The results of the study further lent credence to employee green creativity as a mediation path for such a relationship. Furthermore, customer involvement was found to fortify the linkage of green EO with employee green creativity and the linkage of employee green creativity with green service innovation perceptions.

Practical implications
The results suggest to hotel organizations how to optimally translate their green entrepreneurial strategy into new green services that meet customer preferences and societal expectations.

Originality/value
This inquiry extends the hospitality management literature by linking green EO to green service innovation of hospitality organizations as well as identifying the mediation and moderation mechanisms underlying this link.
Transformational leadership, integration and supply chain risk management in Vietnam's manufacturing firms
Authors: Phung Thi Bich Phuong , Kim Sungsu , Chu Chia Chia 
Published: May 2022

PurposeDue to an increase in vulnerability, supply chain risk management (SCRM) has gained the attention of both researchers and practitioners. Although different approaches have been widely used to discuss the implementation of risk management, the impacts of leadership factors on SCRM have received little attention. To fill this gap in the literature, this study aims to examine whether transformational leadership and integration facilitate SCRM and enhance performance.Design/methodology/approachUsing 261 Vietnamese manufacturing companies as sample, this study applies partial least squares based structural equation modeling (SEM) to test the proposed hypotheses.FindingsThis study demonstrates three contributions for exist leadership and supply chain literature. First, the characteristics of transformational leadership effectively facilitate the internal and external integration in supply chain with higher responsiveness, visibility and integration. Second, transformational leadership has indirectly effect to supply chain risk management practice (SCRMP) throughout supply chain integration (SCI). Additionally, three dimensions of integration enable SCRM and partially mediate the relationship between transformational leadership and SCRM. Furthermore, SCRM not only plays a partially mediating role in the relationship between internal integration, customer integration and supply chain performance but also fully mediates the relationship between supplier integration and supply chain performance.Practical implicationsThis study addresses that the paper extends the content of the relationship between transformational leadership and SCI by three integration dimensions among of exist literature. Transformational leadership should be literarily included into part of leadership strategy on SCRMPs since it is shown to have an indirectly positive improvement effect on SCRM. In addition, the paper is targeted the supply chain downstream performance (SCDP) with integration and risk management with the concept of considering downstream performance is a key section to confront the external stakeholder and customers, Finally, the authors emphasized companies should be aware of the importance about how to include transformational leadership, SCI and SCRMP into its supply chain management.Originality/valueThis study contributes to the SCRM literature by empirically examining the effect of transformational leadership and SCI on SCRM and performance in Vietnam, which is few and far better than that of developed countries.