bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers and facilitators of experiencing pregnancy and motherhood with congenital heart disease: A secondary qualitative analysis
Authors: Ghizzardi Greta , Caruso Rosario , Barello Serena , Flocco Serena Francesca , Arrigoni Cristina , Baroni Irene , Nania Tiziana , Dellafiore Federica 
Published: July 2022

AbstractAimsTo explore and describe perceived factors that favour or hinder the challenges faced by mothers with congenital heart disease during pregnancy and motherhood.DesignA secondary qualitative analysis, according to the interpretative phenomenological analysis approach.MethodsA previous study by Flocco et al., 2020 led us to identify that this population share risks, fear, worries and challenges related to pregnancy. To better understand two a priori themes, barriers and facilitators, we adopted The Standards for Reporting Qualitative Research guidelines, and the processes of credibility, transferability and dependability guaranteed the rigour.ResultsThe perceived barriers that were identified from the twelve semi‐structured interviews were mainly identified in clinical and psychological risks, uncertainty about the future. The main facilitators were identified in positive mental attitude, self‐motivation, trust in support by clinicians and nurses.ConclusionThe study results confirmed two main a priori themes, revealing that CHD women perceive considerable obstacles and figure out facilitators to face the difficulties encountered in their path to become mothers.
Challenges and coping strategies of nurses and midwives after maternity leave: A cross‐sectional study in a human resource‐constrained setting in Ghana
Authors: Konlan Kennedy Dodam , Pwavra Joyce Batagidewe Paladaga , Armah‐Mensah Mavis , Konlan Kennedy Diema , Aryee Rita , Narkotey Stephen 
Published: July 2022

AbstractAimThis study examined the challenges and coping strategies adopted by nurses and midwives after child birth when they return to work.DesignA cross‐sectional design was used.MethodTwo hundred nurses and midwives with history of maternity leave were recruited from the Korle‐Bu Teaching Hospital to take part in this study. Data were collected using a pre‐tested self‐administered questionnaire. The data were analysed with the aid of Stata 13.0.ResultsMost of the respondents claimed that they received support from relatives, day care centres and paid house helps while they resumed work. Seventy percent of the respondents indicated that they were given off day when they needed to send their child for postnatal care. Nurses and midwives depend on family members, paid house helps and day care centres to help them cater for their babies. It is recommended that hospitals set‐up day care centres and breastfeeding bays attached to the institutions.
Quantitative proteome remodeling characterization of two human reference pluripotent stem cell lines during neurogenesis and cardiomyogenesis
Authors: Nam Ki Hong , Ordureau Alban 
Published: July 2022

AbstractHuman pluripotent stem cells (PSCs) have become popular tools within the research community to study developmental and model diseases. While many induced‐PSCs (iPSCs) from various genetic background sources are currently available, scientific advancement has been hampered by the considerable phenotypic variations observed between different iPSC lines. A recent collaborative effort selected a novel iPSC line to address this and encourage the adoption of a standardized iPSC line termed KOLF2.1J. Here, leveraging the multiplexing power of isobaric labeling, we systematically investigate, at the 10k proteome level, the relative protein abundance profiles of the KOLF2.1J reference iPSC line upon two distinct cell state differentiation trajectories. In addition, we side‐by‐side systematically compare this line with the H9 line, an established embryonically derived PSC line that we previously characterized. We noticed differences in the basal proteome of the two cell lines and highlighted the differentially expressed proteins. While the difference between the cell line's proteome subsisted upon differentiation, the global proteome remodeling trajectory was highly similar during the tested differentiation routes. We thus conclude that the KOLF2.1J line performs well at the proteome level upon the neuro and cardiomyogenesis differentiation protocol used. We believe this dataset will serve as a resource of value for the research community.
Mechanism of the phosphine‐catalyzed [3 + 3] annulation with MBH carbonates as the potential dipoles
Authors: Li Tiantian , Chen Zitong , Liu Jiying , Sun Tianhua , Xia Hui , Zhang Wenjing 
Published: July 2022

AbstractThe [3 + 3] cylcloaddition/annulation is an important complementary for construction of six‐membered ring. With addition of organophosphine to the Morita‐Baylis‐Hillman (MBH) carbonate, a potential C3 synthon can be furnished. In this work, the catalytic mechanisms for using this synthon as the nucleophilic or electrophilic dipole to react with the cyclohexa‐2,5‐dienone‐substituted benzenesulfonamide are studied by the density functional theory method. The computational results reveal that the nucleophilic addition of the amide anion to the allylic phosphonium is more favorable than the electrophilic addition of alkenyl in the benzenesulfonamide with the allylic phosphorus ylide. Namely, the allylic phosphonium adduct, rather than the allylic phosphorus ylide that is generated by deprotonation of the allylic phosphonium, is more likely to act as the potential dipole. The global reactivity index calculations indicate that species involved in the favored pathway have better reactivities (both in nucleophilicity and electrophilicity), especially the significantly higher nucleophilicity of the amide anion.
Computational characterization of homologous ligands binding to a deep hydrophobic pocket in Shigella flexneri pilot protein MxiM
Authors: Zhu Shun 
Published: July 2022

AbstractThe type III secretion system (T3SS) is an important molecular machinery in gram‐negative bacteria Shigella flexneri as it provides ways for translocating virulence factors from the bacteria into host cells, eventually leading to severe disease symptoms such as bacillary dysentery. Due to the rising concerns of antibiotics resistance in bactericidal strategy, the anti‐virulence strategy that primarily targets the T3SS components becomes an attractive alternative. MxiM, the secretin pilot protein of Shigella flexneri, binds the secretin MxiD and facilitates the formation of the secretin ring in outer membrane in T3SS assembly. MxiM harbors a large hydrophobic pocket that has been shown to be important in MxiM‐MxiD interaction. In this work, I examined the ligand binding property of MxiM by performing molecular dynamics (MD) simulations of the association between MxiM and a series of hydrophobic ligands, with simulation time amounted to 30 μs. MD simulations successfully captured spontaneous ligand binding events in 153 of the 300 trajectories. The ligand binding can be categorized into two types: a fast type, in which the ligand binds quickly into the hydrophobic pocket and a slow type, in which the ligand forms an encounter complex with the protein before binding into the hydrophobic pocket. Using the MxiM‐ligand binding poses captured in MD simulations, I additionally performed umbrella‐sampling MD simulations with total simulation time amounted to 63 μs to obtain protein–ligand binding free energies. The relationship between the ligand binding free energy and ligand size appears to be nonlinear and exhibits an exponential decay pattern. In summary, I performed computational characterization of MxiM‐hydrophobic ligand binding capabilities and properties, which may provide valuable insights into designing anti‐bacterial medicine against antibiotics resistance in Shigella flexneri.
Moment based model predictive control for linear systems: Additive perturbations case
Authors: Saltık Muhammed Bahadır , Özkan Leyla , Weiland Siep 
Published: July 2022

AbstractIn this article, we present a novel linear model predictive control (MPC) strategy for controlling uncertain dynamical systems. The moment based MPC strategy is based on the (centralized) moments of the stochastic cost and constraint functions. We show that moment based MPC formulations yield computationally tractable predictive control problems, due to the explicit analytic expressions of the moments and linearity in the dynamics. This article considers (i) the output regulation MPC configuration, where the output is steered towards a reference and state vector is not correctly accessible to the controller at the decision instants; (ii) the moment based MPC formulation with uncertainties that are non‐Gaussian random variables, and (iii) bound and polytopic constraints in the uncertain MPC problem subject to either Gaussian disturbances or uncertainties with symmetric distributions. We demonstrate the effectiveness of the proposed MPC technique on simulation examples such as a double integrator system and a quadruple tank system.
Effect of Commercial Gas Diffusion Layers on Catalyst Durability of Polymer Electrolyte Fuel Cells in Varied Cathode Gas Environment
Authors: Khedekar Kaustubh , Satjaritanun Pongsarun , Stewart Sarah , Braaten Jonathan , Atanassov Plamen , Tamura Nobumichi , Cheng Lei , Johnston Christina M. , Zenyuk Iryna V. 
Published: July 2022

AbstractGas diffusion layers (GDLs) play a crucial role in heat transfer and water management of cathode catalyst layers in polymer electrolyte fuel cells (PEFCs). Thermal and water gradients can accelerate electrocatalyst degradation and therefore the selection of GDLs can have a major influence on PEFC durability. Currently, the role of GDLs in electrocatalyst degradation is poorly studied. In this study, electrocatalyst accelerated stress test studies are performed on membrane electrode assemblies (MEAs) prepared using three most commonly used GDLs. The effect of GDLs on electrocatalyst degradation is evaluated in both nitrogen (non‐reactive) and air (reactive) gas environments at 100% relative humidity. In situ electrochemical characterization and extensive physical characterization is performed to understand the subtle differences in electrocatalyst degradation and correlated to the use of different GDLs. Overall, no difference is observed in the electrocatalyst degradation due to GDLs based on polarization curves at the end of life. But interestingly, MEA with a cracked microporous layer (MPL) in the GDL exhibited a higher electrocatalyst loading loss, which resulted in a lower and more heterogeneous increase in the average electrocatalyst nanoparticle size.
Bending‐Insensitive Intrinsically Flexible Ultraviolet Encoding Devices Based on Piezoelectric Nanogenerator‐Supplied Liquid Crystalline Polymer Fabrics
Authors: Zheng Xiaoxiong , Liu Zhefeng , Wang Rui , Chen Aihua 
Published: July 2022

AbstractIt is significantly challenging for state‐of‐the‐art wearable electronics to stably monitor physicochemical signals under dynamic motions. Herein, a bending‐insensitive, self‐powered, and intrinsically flexible UV detector has been realized based on well‐designed oriented composite fabrics, consisting of ionic liquid (IL)‐containing liquid crystalline polymers (ILCPs) and piezoelectric poly(vinylidene fluoride‐trifluoroethylene) [P(VDF‐TrFE)] nanogenerators. The novel composite fabrics establish effective UV illuminance‐internal stress‐electric signal conversion by coupling resistive and piezoelectric effects, with a fast response time of 190 ms. Particularly, benefiting from the intrinsic flexibility of composite fabrics, the ILCP/P(VDF‐TrFE) device can maintain stable performance under dynamic bending even if the frequency is up to 2.5 Hz, with a bending insensitivity of less than 1% performance variation under 1.0 mW cm−2 UV light. Combined with the Internet of Things and the American Standard Code for Information Interchange (ASCII), wearable encoding electronics have been successfully implemented with a printing speed of 3.2 s per character under dynamic bending.
Metallopolymer Particle Engineering via Etching of Boronate Polymers toward High‐Performance Overall Water Splitting Catalysts
Authors: Wu Tong , Li Yaying , Hong Jing , He Liu , Mao Jie , Wu Xiaoling , Zhou Xiangfu , Zeng Peixin , Zeng Birong , Xu Yiting , Luo Weiang , Chen Guorong , Yuan Conghui , Dai Lizong 
Published: July 2022

AbstractMetallopolymers combine the property features of both metallic compounds and organic polymers, representing a typical direction for the design of high‐performance hybrid materials. Here, a highly adaptive etching method to create pores and cavities in the metallopolymer particles is established. Starting from boronate polymer (BP) and inorganic@BP core–shell particles, porous, hollow, and yolk–shell metallopolymer particles can be fabricated, respectively. By taking advantage of the easy control over composition and pore/cavity structure, these metallopolymer particles provide a universal platform for the fabrication of nitrogen, boron co‐doped carbon nanocomposites loaded with metals (M‐NBCs). The as‐prepared M‐NBCs exhibit remarkable catalytic activities toward oxygen evolution reaction and hydrogen evolution reaction. An alkaline overall water splitting cell assembled by using M‐NBCs as the anode and cathode can be driven by a single AAA battery. The proposed strategy for the construction of metallopolymer composites may enlighten for the design of complex hybrid nanomaterials.
Bidirectional Lithiophilic Gradients Modification of Ultralight 3D Carbon Nanofiber Host for Stable Lithium Metal Anode
Authors: Li Tong , Gu Sichen , Chen Likun , Zhang Lihan , Qin Xianying , Huang Zhijia , He Yan‐Bing , Lv Wei , Kang Feiyu 
Published: July 2022

AbstractUsing 3D host is an effective way to solve the dendrite growth problem and accommodate volume changes of lithium (Li) metal anode. However, the preferred Li deposition on the top surface leads to the Li metal agglomeration at the surface. In addition, the large weight of the 3D host also greatly decreases the capacity based on the whole anode. Herein, a bidirectional lithiophilic gradient modification, including a top‐down ZnO gradient and a bottom‐up Sn gradient, is applied to an ultralight 3D carbon nanofiber host (density: 0.1 g cm−3) and ensures the evenly filling lithium deposition in the 3D host. ZnO transforms into highly ionic conductive Li–Zn alloy and Li2O during cycling, enhancing the Li‐ion transportation from top to bottom. The metallic Sn also lowers the Li nucleation potential, guiding the preferential Li deposition from the bottom. With such a host, a stable CE of 97.5% over 100 cycles at 1 mA cm−2 and 3 mAh cm−2 is achieved, and the full battery also delivers good cycling stability over 300 cycles with a high CE of 99.8% coupled with high loading LiFePO4 cathode (10 mg cm−2) and low N/P ratio (≈3).
Floating Hydrogel Beads Made by Droplet Impact
Authors: Chu Yanji , Liao Shenglong , Wang Qianci , Ma Yingchao , Wang Yapei 
Published: July 2022

AbstractDroplet impact is a ubiquitous natural phenomenon that has been widely utilized to inspire and facilitate many industrial applications. Compared to the widely studied water droplet impact onto identical liquid surfaces, the water droplet impact onto an oil layer floating on a water bath (OLW) receives far less attention and its potential application has never been exploited. Herein, the process of water droplet impact onto the OLW is investigated with emphasis on the metastable states and potential applications. It is found that the dramatic deformation of the oil–water interface caused by the water droplet impact leads to two metastable states: oil in water in oil in water (O/W/O/W) and oil in water in oil (O/W/O). Through the subsequent introduction of gelation process, the metastable states can be frozen into floating hydrogel beads with similar shape to the roly‐poly toys, which are attempted in gastric retentive drug delivery and algae bloom control. Specifically, the floating hydrogel beads perform well in gastric retentive drug delivery in vitro due to their inherent slow‐release properties and floating capability. In addition, the floating hydrogel beads loading photocatalysts can capture more sunshine, and exhibit high photocatalytic efficiency, which is thus responsible for efficient algae bloom control.
Rational Design of WSe2/WS2/WSe2 Dual Junction Phototransistor Incorporating High Responsivity and Detectivity
Authors: Luo Zhongtong , Yang Mengmeng , Wu Dongsi , Huang Zihao , Gao Wei , Zhang Menglong , Zhou Yuchen , Zhao Yu , Zheng Zhaoqiang , Li Jingbo 
Published: July 2022

AbstractThe excellent semiconducting properties and ultrathin morphological characteristics allow van der Waals (vdW) heterostructures based on 2D materials to be promising channel materials for the next‐generation optoelectronic devices, especially in photodetectors. Although various 2D heterostructure‐based photodetectors have been developed, the unavoidable trade‐off between responsivity and detectivity remains a critical issue for these devices. Here, an ingenious phototransistor based on WSe2/WS2/WSe2 dual‐vdW heterostructures is constructed, performing both high responsivity and detectivity. In the charge neutrality point (gate voltage of −15 V and bias voltage of 1 V), this device demonstrates a pronounced photosensitivity, accompanying with high detectivity of 1.9 × 1014 Jones, high responsivity of 35.4 A W−1, and fast rise/fall time of 3.2/2.5 ms at 405 nm with power density of 60 µW cm−2. Density functional theory calculations, energy band profiles, and optoelectronic characteristics jointly verify that the high performance is ascribed to the distinctive device design, which not only facilitates the separation of photogenerated carriers but also produces a strong photogating effect. As a feasible application, an automotive radar system is demonstrated, proving that the device has considerable potential for application in vehicle intelligent assisted driving.
Control of Quantum Noise: On the Role of Dilations
Authors: Burgarth Daniel , Facchi Paolo , Hillier Robin 
Published: July 2022

AbstractWe show that every finite-dimensional quantum system with Markovian (i.e. GKLS-generated) time evolution has an autonomous unitary dilation which can be dynamically decoupled. Since there is also always an autonomous unitary dilation which cannot be dynamically decoupled, this highlights the role of dilations in the control of quantum noise. We construct our dilation via a time-dependent version of Stinespring in combination with Howland’s clock Hamiltonian and certain point-localised states, which may be regarded as a C*-algebraic analogue of improper bra-ket position eigenstates and which are hence of independent mathematical and physical interest.
Hydroacoustic Signals Originating from Marine Volcanic Activity at Kadovar Island, Papua New Guinea, Recorded by the Comprehensive Nuclear-Test-Ban Treaty International Monitoring System
Authors: Matsumoto Hiroyuki , Zampolli Mario , Haralabus Georgios , Stanley Jerry , Robertson James , Özel Nurcan Meral 
Published: July 2022

AbstractHydroacoustic signals originating from marine volcanic activity at Kadovar Island (Papua New Guinea), recorded by the Comprehensive Nuclear-Test-Ban Treaty (CTBT) International Monitoring System (IMS) hydroacoustic (HA) station HA11 Wake Island (USA), are examined herein. Episodes of high volcanic activity were identified on two occasions, separated by a period of 1 month. The events studied pertain to an initial eruption series during a period between January and February 2018. Based on local visual observations, the Kadovar volcano began to erupt at the summit and then created a new vent spot near the coast. This series of events also included the collapse of a lava dome. Direction-of-arrival estimates for the hydroacoustic signals detected at HA11 were computed using a cross-correlation technique, which allowed for the discrimination between hydroacoustic signals originating from the Kadovar volcanic activity and numerous other hydroacoustic signals attributed to seismic activity in the Pacific Ocean. The Kadovar-related seismic signals could not be identified by regional IMS seismic stations, suggesting a submarine origin of these events. On the other hand, hydroacoustic signals originating from the Kadovar volcanic activity were identified by the seismometer at Manus Island, which is located between Kadovar and HA11. The study suggests that a series of explosive bursts followed by an unusual rumble and a broadband signal plus rumble may constrain the time of the lava dome collapse event at Kadovar Island to 00:30 UTC, 00:33 UTC, and 00:46 UTC on 09 February 2018. Given the compatibility of this observation with the tsunami generation reported by eyewitnesses on the nearby island of Blup Blup, the authors interpret this particular hydroacoustic signal as being a remote observation of this tsunamigenic event. The objective of this study was to assess the potential added value of IMS hydroacoustic data for remote surveillance of geohazards in otherwise sparsely monitored areas.
Television and fertility: evidence from a natural experiment
Authors: Bönisch Peter , Hyll Walter 
Published: July 2022

AbstractIn this paper, we study the effect of television exposure on fertility. We exploit a natural experiment that took place in Germany after WWII. For topographical reasons, Western TV programs, which promoted one/no child families, could not be received in certain parts of East Germany. We find robust evidence that access to West German TV results in lower fertility. This conclusion is robust to alternative model specifications and different data sets. Using individual level information on TV consumption, we employ IV techniques to estimate the direct effect of Western TV consumption on fertility. By using aggregate level fertility data, we furthermore show the robustness of our analysis in a difference-in-difference setting. Our results suggest that individual fertility decisions are affected by role models or information about other ways of life promoted by media.
Impact of PhD Degree Versus Non‐PhD Research Fellowship on Future Research Productivity Among Academic Cardiothoracic Surgeons
Authors: Bajaj Simar S. , Wang Hanjay , Williams Kiah M. , Heiler Joseph C. , Pickering Joshua M. , Manjunatha Keerthi , O'Donnell Christian T. , Sanchez Mark , Boyd Jack H. 
Published: July 2022

AbstractBackgroundA PhD degree can offer significant research experience, but previous studies yielded conflicting conclusions on the relationship between a PhD degree and future research output. We compared the impact of a PhD degree versus research fellowship (RF) training on research productivity in cardiothoracic surgeons, hypothesizing that training pathways may influence potential associations.MethodsCT surgeons practicing at all accredited United States CT surgery training programs in 2018 who pursued dedicated time for research (n = 597), including earning a PhD degree (n = 92) or completing a non‐PhD RF (n = 505), were included. To control for training pathways, we performed subanalyses of U.S. medical school graduates (n = 466) and international medical school graduates (IMGs) (n = 131). Surgeon‐specific data were obtained from publicly available sources (e.g., institutional webpages, Scopus).ResultsPhD surgeons published greater total papers (68.5 vs. 52.0, p = 0.0179) and total papers per year as an attending (4.6 vs. 3.0, p = 0.0150). For U.S. medical school graduates, there were 40 PhD surgeons and 426 non‐PhD RF surgeons; both groups published a similar number of total papers (64.5 vs. 54.0, p = 0.3738) and total papers per year (3.2 vs. 3.0, p = 0.7909). For IMGs, there were 52 PhD surgeons and 79 non‐PhD RF surgeons; the PhD surgeons published greater total papers (80.5 vs. 45.0, p = 0.0101) and total papers per year (5.7 vs. 2.7, p = 0.0037).ConclusionCT surgeons with dedicated research training are highly academically productive. Although a PhD degree may be associated with enhanced career‐long research productivity for IMGs, this association was not observed for U.S. medical school graduates.