bluuebunny/crossref_metadata_2025_split huggingface dataset:
Automated Quality Control of AERONET-OC LWN Data
Authors: Zibordi Giuseppe , D’Alimonte Davide , Kajiyama Tamito 
Published: August 2022

Abstract
Quality control (QC) practices are a fundamental requirement for any measurement program targeting the delivery of high-quality data. In agreement with such a need, the Ocean Color component of the Aerosol Robotic Network (AERONET-OC) includes a number of QC steps ensuring the delivery of normalized water-leaving radiance LWN spectra at incremental accuracy levels identified as level 1.0, level 1.5, and level 2.0. Currently, the final QC step allowing for rising level 1.5 LWN spectra to level 2.0 implies the execution of an expert-based procedure, which is extremely time consuming and naturally undergoes subjective decisions on dubious cases. These limitations solicited the development of an automated procedure, so-called , mimicking the steps supporting an expert analyst during the final QC of AERONET-OC LWN spectra. applies hierarchical tests to check (i) the relative consistency of level 1.5 LWN spectra (called candidates) with respect to LWN reference spectra (called prototypes) constructed using LWN spectra formerly and independently quality controlled; (ii) the absence of any pronounced spectral feature in portions of each LWN candidate spectrum expected to exhibit a regular shape; and additionally, when applicable, (iii) the temporal consistency of the LWN candidate spectrum with respect to close-in-time spectra as a criterion to further strengthen the quality of data. performance has been verified using LWN spectra from AERONET-OC measurement sites representative of various water types embracing oligotrophic/mesotrophic waters dominated by chlorophyll-a concentration and coastal waters exhibiting increasing levels of optical complexity. has shown an acceptance rate of AERONET-OC level 1.5 LWN candidate spectra varying between approximately 89% and 93% with agreement in the range of 88%–93% with respect to the LWN spectra independently quality controlled through the expert-based procedure. The additional capability of to rank the fully quality-controlled LWN spectra combining weights depending on the various tests, anticipates the possibility to best support applications with diverse accuracy needs. Finally, acceptance rates of for LWN prototype spectra built using level 1.5 data, an alternative to fully quality-controlled level 2.0, have shown values generally increased by less than 1%. This indicates the possibility to lessen the constraint implying the existence of reference level 2.0 LWN data for the relative-consistency test at the expense of a fairly low reduction in accuracy.
Factors associated with limitations in daily life and at work in a population with shoulder pain
Authors: Godeau Diane , Fadel Marc , Descatha Alexis 
Published: August 2022

Abstract
Background
Shoulder pain, which is a widespread condition, can lead to participation restrictions in daily and professional life. However, there are few studies focusing on the differences between daily life limitations and work limitations. This study aims at identifying the factors associated with limitations in personal and professional life in a population of working age suffering from shoulder pain.

Methods
A sample of working age job seekers and workers with shoulder pain was drawn from the last general population cross-sectional French study on disability. Limitations were categorized depending on whether they related to daily life and/or work. The variables assessed were age, sex, state of health, activity restrictions, need for accommodation, and aggravating living conditions or aggravating working conditions. Separate Quasi-Poisson regressions were performed for each type of limitation.

Results
The sample consisted of 795 individuals of which 33.7% had no limitation, 21.7% were limited in daily life, 6.0% at work, and 38.6% in both. Factors significantly associated with daily life limitations and work limitations and their computed Prevalence Ratios (PR) were the need for accommodation (PR = 2.16), activity restrictions (PR = 2.28), perceived poor health (PR = 2.42) and low income (PR = 1.64). Aggravating living conditions and aggravating working conditions were associated with daily life limitations (PR of 1.69 and 0.63 respectively).

Conclusions
The present study identifies factors associated with disability in a population with shoulder pain. Further research should be carried out in order to study health-related periods of cessation of work.
Implementing screening for hypertension in archetypal HIV primary care: a mixed-methods assessment
Authors: Buzaalirwa Lydia , Nambala Lydia , Banturaki Grace , Amor Penninah Iutung , Katahoire Anne , Geng Elvin , Semeere Aggrey 
Published: August 2022

AbstractBackgroundHigh prevalence of HIV and hypertension in sub-Saharan Africa puts adults living with HIV (ALWH) at high risk of end-organ complications. Both World Health Organization (WHO) and national guidelines recommend screening and treatment of hypertension among ALWH on antiretroviral therapy (ART). We evaluated the implementation of hypertension screening among adults on ART at three Uganda Cares Primary care facilities.MethodsUsing a sequential explanatory mixed-methods approach, we reviewed patient records, and interviewed both patients and providers during 2018 and 2019. We obtained demographics, clinical and blood pressure (BP) measurements via records review. We estimate the period prevalence of screening and use adjusted modified Poisson regression models to evaluate predictors of screening. In-depth interviews were analysed using a thematic approach to explain the observed prevalence and predictors of BP screening.ResultsRecords for 1426 ALWH were reviewed. Patients had a median age of 35 years and 65% of them were female. Most were on ART (89% on first-line) with a median duration of 4 years. Only 262 (18%) were overweight or obese with a body mass index (BMI) > 25 Kg/M2. In 2017 or 2018 patients made a median of 3 visits and 783 patients had a BP recorded, hence a period prevalence 55%. Older age, male sex, more clinic visits, and clinic site were associated with screening in the adjusted analyses. Erratic BP screening was corroborated by patients’ and providers’ interviews. Challenges included; high patient numbers, low staffing, provider apathy, no access to treatment, and lack of functioning of BP equipment.ConclusionAlmost half of regular HIV clinic attendees at these prototypical primary care HIV clinics were not screened for hypertension for a whole year. Improving BP screening requires attention to address modifiable challenges and ensure local buy-in beyond just providing equipment.
Efficacy and safety of triplet chemotherapy plus anti-EGFR agents in metastatic colorectal cancer: a systematic review and meta-analysis
Authors: Wu Qian , Wang Huan , Zhang Suqin , Zeng Yifei , Yang Wei , Pan Wenjun , Hong Guodai , Gao Wenbin 
Published: August 2022

Abstract
Background
To date, the optimal treatment for potentially resectable metastatic colorectal cancer (mCRC) patients has yet to be determined. Encouraging results have been reported in studies exploring the efficacy of triplet chemotherapy plus anti-epidermal growth factor receptor (anti-EGFR) target agents. Thus, we conducted a meta-analysis to evaluate the efficacy and safety of triplet chemotherapy plus anti-EGFR target agents.

Methods
We systematically searched the PubMed, Embase, and Web of Science databases from December 2004 to October 2021 for studies examining the efficacy of triplet chemotherapy plus anti-EGFR target agents in mCRC patients. The primary outcomes were the objective response rate (ORR) and R0 resection rate (R0RR), and the secondary outcomes were median progression-free survival (mPFS), median overall survival (mOS), and toxicity. Data were analyzed with R software 4.1.2.

Results
Fourteen studies comprising 762 patients with mCRC were included in this meta-analysis. Analysis with a random effects model revealed that after treatment with triplet chemotherapy plus anti-EGFR target agents, the pooled ORR was 82% (95% CI= 76–88%, I2= 76%), and the pooled R0RR of colorectal liver metastasis (CLM) was 59% (95% CI= 49–68%, I2= 60%). The mPFS ranged from 9.5 to 17.8 months, and the mOS ranged from 24.7 to 62.5 months. A total of 648 grade 3 or 4 adverse events were reported; the most commonly reported events were diarrhea (174/648), neutropenia (157/648), and skin toxicity (95/648), which had pooled prevalence rates of 29% (95% CI= 20–39%, I2= 84%), 28% (95% CI= 20–37%, I2= 77%), and 17% (95% CI= 11–24%, I2= 66%), respectively.

Conclusions
Triplet chemotherapy plus anti-EGFR agents therapy seems to be capable of increasing the ORR of mCRC patients and the R0RR of CLM patients. The toxicity of this treatment is manageable. High-quality randomized controlled trial (RCT) studies are required for further validation.
An examination of the medicalization and pharmaceuticalization processes of anxiety and depressive disorders in Belgium between 2004 and 2013: how may both disorders be intertwined?
Authors: Kilian Van Looy , de Velde Sarah Van 
Published: August 2022

AbstractBackgroundWhile medicalization and pharmaceuticalization trends of feelings of anxiety and depression have been described in great detail, an empirical examination of these trends is to date lacking. The current study fills this gap in the literature by mapping the use of psychotropic medicines for feelings of anxiety and depression between 2004 and 2013 in Belgium, as well as by examining whether a social gradient might act as a mediator.MethodsWe analyzed data from three repeated cross-sectional waves (2004, 2008, and 2013) of the Belgian National Health Interview Survey (HIS). Multinomial logistic regression was applied to estimate odds in psychotropic drugs use over the observed period.ResultsUsing an ideal-typical distinction between traditional anxiety drugs (psycholeptics) and depression drugs (psychoanaleptics), we found that treatment methods for feelings of anxiety and depression were converging. Persons having feelings of anxiety consumed less psycholeptic drugs, in favor of psychoanaleptic drugs throughout the observed period. Moreover, these results were partially mediated by educational level. Persons with higher education were less likely to consume psychotropic drugs than those with lower education, suggesting a trend of demedicalization for feelings of anxiety and depression.LimitationsOur study observes a limited period, makes use of an ideal typical distinction between psycholeptic and psychoanaleptic drugs, and measurements may be biased by response-bias due to psychotropic drugs use.ConclusionOur study shows that psycholeptics increasingly give way to psychoanaleptics in the treatment of both anxiety and depression, despite several scientists calling their effectiveness for both disorders into question.
Zoonoses and gold mining: A cross-sectional study to assess yellow fever immunization, Q fever, leptospirosis and leishmaniasis among the population working on illegal mining camps in French Guiana
Authors: Douine Maylis , Bonifay Timothée , Lambert Yann , Mutricy Louise , Galindo Muriel Suzanne , Godin Audrey , Bourhy Pascale , Picardeau Mathieu , Saout Mona , Demar Magalie , Sanna Alice , Mosnier Emilie , Blaizot Romain , Couppié Pierre , Nacher Mathieu , Adenis Antoine , Suarez-Mutis Martha , Vreden Stephen , Epelboin Loïc , Schaub Roxane 
Published: August 2022

Background
Most emerging pathogens are zoonoses and have a wildlife origin. Anthropization and disruption of ecosystems favor the crossing of inter-species barriers. We hypothesize that the marginalized population of undocumented goldminers in the Amazon is at risk of acquiring zoonoses.

Method
A multicentric cross-sectional study included consenting gold-mining adult workers in 2019. A clinical examination recorded dermatological signs of leishmaniosis and past history of yellow fever vaccination. Biological tests were performed for yellow fever, Q fever and leptospirosis serologies. Additional blood samples from a previous study in 2015 were also tested for leptospirosis.

Results
In 2019, 380 individuals were included in the study, along with 407 samples from the 2015 biological collection. The seroprevalence of leptospirosis was 31.0% [95%CI = 26.4–35.5] in 2015 and 28.1% [23.5–32.7] in 2019. The seroprevalence of Q fever was 2.9% [1.2–4.6]. The majority of participants reported being vaccinated against yellow fever (93.6%) and 97.9% had seroneutralizing antibodies. The prevalence of suspected active mucocutaneous leishmaniasis was 2.4% [0.8–3.9].

Discussion
These unique data shed new light on the transmission cycles of zoonoses still poorly understood in the region. They support the existence of a wild cycle of leptospirosis but not of Q fever. Leishmaniasis prevalence was high because of life conditions and tree felling. High yellow fever vaccine coverage was reassuring in this endemic area. In the era of global health, special attention must be paid to these vulnerable populations in direct contact with the tropical ecosystem and away from the health care system.
Phonologische Kompetenz beim auditiven Dekodieren – ein konkretes Beispiel aus dem Bereich der Prosodie
Authors: Morf Miriam 
Published: August 2022

Zusammenfassung
Ausgehend von der Rolle des Hörverstehens im Fremdsprachenunterricht soll in diesem Beitrag die Bedeutung der phonologischen Kompetenz im Allgemeinen und die der Prosodie im Besonderen für die Erleichterung des auditiven Dekodierungsprozesses veranschaulicht werden. Anschließend wird die neue Skala der phonologischen Kontrolle im Begleitband des GER vorgestellt, die im Gegensatz zur bisherigen Skala auch die suprasegmentalen Aspekte der Sprache betont. Diese spielen in der rezeptiven Phase eine entscheidende Rolle bei der Zerlegung des Sprachstroms in kleinere Bedeutungseinheiten, die im Kurzzeitgedächtnis leichter zu verarbeiten sind und somit den Dekodierungsprozess unterstützen. Schließlich werden Mikro-Hörübungen vorgestellt, die mit authentischem Material erstellt wurden und die rezeptive prosodische Kompetenz in Deutsch als Fremdsprache fördern sollen.
Höflichkeit im Mikrokosmos eines Sanatoriums. Vergleich Russland-Österreich
Authors: Rathmayr Renate 
Published: August 2022

SummaryIn the context of contrastive pragmatics, some expressions of politeness in the special environment in a sanatorium are dealt with in this article. In particular these three forms: addressing and greeting known or unknown people, communicativeness, i. e. the convention of entering into a conversation with strangers or avoiding it, and gallantry, i.e. courteous non-verbal actions like holding a door open for those who follow, pushing a chair into position, clearing a place.The study is based on participant observation during a 10-day stay in a health resort in the North Caucasus in the summer of 2018 and in Austrian facilities. Oral communication between the medical and other staff with the spa guests and communication between themselves, as well as written announcements and inscriptions of various kinds were analysed.Austria in its self-image is a very polite and hospitable country, Russia perceives itself as very hospitable, but not particularly polite. The comparison of politeness in the microcosm of a sanatorium in the North Caucasus and similar institutions (health resorts / facilities) in Austria did not confirm the assumption of low politeness in Russia. In both cultures, a high level of courtesy and respect could be observed among the staff and among or towards the spa guests. It should also be noted that even if one hears repeatedly of the condescending or even suppressive treatment of members of Caucasian nationalities, in the microcosm of the sanatorium there was an equally respectful attitude towards everyone and no discrimination whatsoever was observed. Whether the findings in a spa facility in another part of Russia would be different still has to be the subject of further investigation.
Interventions to improve the detection of depression in primary healthcare: systematic review
Authors: Habtamu Kassahun , Birhane Rahel , Demissie Mekdes , Fekadu Abebaw 
Published: August 2022

Abstract
Background
Several studies have been conducted on the effect of interventions on the detection of depression in primary healthcare (PHC). Systematic reviews have also been done on the effectiveness of separate interventions to improve clinicians’ recognition of depression in the PHC setting. However, systematic reviews are not done on the comparative effectiveness of several interventions together. This study, therefore, aimed at synthesizing the global evidence on the effectiveness of interventions to improve the detection of depression in primary healthcare.
Methods
We searched PubMed, Embase, PsycINFO, Web of Science, Cochrane Database of Systematic Reviews, Global Index Medicus, African Index Medicus and African Journals Online, from the inception of the databases to until the 4th week of April 2020. We also searched references of the included articles. We included randomized controlled trials, cluster randomized trials or quasi-experimental studies, which evaluated the effectiveness of an intervention to improve detection of depression in the PHC setting. Two of the review authors independently extracted data from the included studies. The methodological quality of the included studies was assessed using the Assessment Tool for Quantitative Studies developed by the Effective Public Health Practice Project. The protocol for the review was registered on PROSPERO (CRD42020166291).
Results
Of 23,305 records identified, we included 58 articles in the review. Diverse types of interventions were evaluated to improve clinician diagnosis of depression in the PHC setting. Interventions related to implementation of guidelines, screening with feedback, educational interventions which incorporated active learning and clinical practice, and disclosure of screening results were found to be mostly effective. Interventions which combined education, screening and feedback were particularly more effective. Most of the included studies were weak or moderate in their methodological quality.
Conclusions
Our review indicates that implementation of a single type of intervention does not improve the detection of depression in PHC. Combining aspects of each type of intervention which are more effective may be useful. Most of the studies conducted in the area are from high-income countries and are weak in their methodological quality. There is need to conduct more number of rigorous studies, particularly in low and middle-income countries.
Measure the Performance by Analysis of Different Boosting algorithms on Various Patterns of Phishing datasets
Authors: Pandey Mithilesh Kumar , . Sonam , Pal Rekha , Singh Saurabh , Singh Munindra Kumar , Pal Saurabh , Pandey Umesh Kumar , Shukla Arvind Kumar , Pandey Manish Ranjan , Yadav Dhyan Chandra 
Published: August 2022

Abstract
The internet has become an important component of our daily lives. The most common internet service is web surfing. Many individuals use their browser to do things like online shopping, bill payment, cell phone recharge, and banking transactions. Customers confront different security dangers, such as cyber crime, as a result of the widespread usage of this service. Cyber phishing is a type of web threat that entices users to connect with a false website. The main goal of this research paper is to prevent the user's sensitive information. The proposed model is developed in three steps in step1 we choose a dataset to train on, and then test classifiers on the dataset. In step2 we have applied the three classifiers finding phishing detection accuracy and finally step3 after completing all of the predictions, we discovered that XGBoost outperformed AdaBoost and Gradient boosting machine learning algorithms.
Correlates of protection for booster doses of the BNT162b2 vaccine
Authors: Hertz Tomer , Levy Shlomia , Ostrovsky Daniel , Oppenheimer Hannah , Zismanov Shosh , Kuzmina Alona , Friedman Lilach , Trifkovic Sanja , Brice David , Lin Chun-Yang , Cohen-Lavi Liel , Shemer-Avni Yonat , Cohen-Lahav Merav , Amichay Doron , Keren-Naus Ayelet , Voloshin Olga , Weber Gabriel , Najjar-Debbiny Ronza , Chazan Bibiana , McGargill Maureen , Webby Richard , Chowers Michal , Novack Lena , Novack Victor , Taube Ran , Nesher Lior , Weinstein Orly 
Published: August 2022

Abstract
Variants of concern (VOC) of SARS-CoV2 and waning immunity pose a serious global problem. Overall, vaccination and prior infection provide significant protection, but some individuals remain susceptible to infection and severe disease. Rigorously identifying correlates of protection (COP) is necessary to identify these susceptible populations. We conducted a multicenter prospective study assessing the association between serological profiles and the risk for SARS-CoV-2 infection, comparing those vaccinated with three to four doses of Pfizer BNT162b2 vaccine. We identified several IgG and IgA binding markers that were COPs. The strongest COP was reduced IgG levels to RBD mutants and IgA levels to VOCs (three-dose-group HR=6.34, p=0.008; four-dose-group HR=8.14, p=0.018). Most importantly, we identified a subset of vaccinated individuals with low antibody levels that generated a significant boost in neutralizing antibody titers after a fourth dose, but were still at significantly increased susceptibility to infection.
Three-dimensional analysis of modeled facial aging and sexual dimorphism from juvenile to senile age
Authors: Velemínská Jana , Jaklová Lenka Kožejová , Kočandrlová Karolína , Hoffmannová Eva , Koudelová Jana , Suchá Barbora , Dupej Ján 
Published: August 2022

AbstractFactors such as growth, aging, and health have known associations with changes in facial soft tissues. A detailed understanding of facial soft tissue ontogenetic development is important in a variety of scientific disciplines dealing with facial reconstruction, forensic identification, and ageing prediction. The main goals of this study were (1) to use geometric morphometrics to model facial aging, (2) to model the development of shape facial sexual dimorphism, and (3) to use classic morphometrics to depict facial differences between individual age categories. Our study was based on the form and shape analysis of three-dimensional facial surface models of 456 individuals aged 14–83 years. The facial models were obtained using a structured light-based optical scanner and divided into four age categories (juvenile, younger adult, middle adult, and older adult). The methodology was based on geometric and classic morphometrics including multivariate statistics. Aging in both sexes shared common traits such as more pronounced facial roundness reducing facial convexity, sagging soft tissue, smaller visible areas of the eyes, greater nose, and thinner lips. Male faces exhibited more even and intense ageing changes. Sexual dimorphic traits tended to diminish in the frontal and orbitonasal area and increase in the gonial area.