bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of micronucleus assay in oral mucosa cells as a suitable biomarker in children exposed to environmental mutagens: theoretical concepts, guidelines and future directions
Authors: Malacarne Ingra Tais , Alpire Maria Esther Suarez , Malinverni Andrea Cristina de Moraes , Ribeiro Daniel Araki 
Published: November 2022

Abstract
In the last decades, the micronucleus assay has been recognized as a suitable biomarker for monitoring populations exposed to many different occupational factors, lifestyle, environmental conditions, radiation exposure, and deleterious effects of pesticides. The objective of this work is to direct the design of future field studies in the assessment of the risk of children exposed to environmental mutagens, radiation, and pesticides. This review sought available information on the analysis of micronuclei in oral cells in children. A literature search for papers investigating DNA damage, genetic damage, oral cells, buccal cells, genotoxicity, mutagenicity and micronucleus was begun in 2000 and is scheduled to be concluded in May, 2022. Briefly, a search of PubMed, MEDLINE, and Google Scholar for a variety of articles was performed. The results showed that there are still few studies that addressed micronuclei of oral cells in children exposed to the most diverse environmental conditions. Only environmental pollution was associated with damage to the genome of oral cells in children. Therefore, researchers need to be calibrated in cell analysis, standardization of field study protocols and the development of new research in the evaluation of children using the micronucleus test as a tool in child biomonitoring.
Large deviation principle for a mixed fractional and jump diffusion process
Authors: Diatta Raphaël , Manga Clément , Diédhiou Alassane 
Published: November 2022

Abstract
We study the asymptotic behavior of a solution of a mixed differential equation driven by independent fractional Brownian motion with Hurst index

H
∈

(
0
;
1
)

{H\in(0;1)}

and compensated Poisson process. This study consists in determining the uniform Freidlin–Wentzell estimates in a temporal distribution space.
Damage and failure analysis of composite stiffened panels under low-velocity impact and compression after impact with damp-heat aging
Authors: Du Changmei , Li Hanhua , Yan Shi , Zhang Qiuhua , Jia Jiale , Chen Xixi 
Published: November 2022

Abstract
The low-velocity impact and compression after the impact of the composite stiffened panels were carried out after damp-heat aging. The experimental results show that reinforcing the ribs can enhance the impact resistance of test pieces after damp-heat aging. After impacting, the specimens were tested in an axial compression. The results show that the ultimate bearing capacity of the specimen is also affected by different located positions of the impact and different aging times. Compared with the intact specimen, the ultimate load-bearing capacity was reduced to 16.83, 12.10, and 17.10% with the specimen aging for 0, 45, and 90 days, respectively, while the impact position located at the intersection of longitudinal and transverse bars has the greatest influence on the damp-heat aging of specimens.
Optimization study of momentum investment strategies under asymmetric power-law distribution of return rate
Authors: Wu Xu , Wang Kun , Zhang Linlin , Peng Chong 
Published: November 2022

Abstract
In the context that the tails of security returns obey an asymmetric power-law distribution, this paper constructs two fractal statistical measures based on fractal theory: fractal expectation and fractal variance. Subsequently, a new momentum strategy is constructed by introducing the fractal measures into the momentum strategy as measures of returns and risks to optimize the selection criterion. Finally, the empirical results show that the new momentum strategy outperforms the traditional momentum strategy and the risk-adjusted momentum strategy, confirming the effectiveness of fractal expectation and fractal variance.
Note on <em>Principia</em>'s *38 on Operations
Authors: Landini Gregory 
Published: November 2022

Principia Mathematica *38 introduces what it calls “Relations and Classes Derived from a Double Descriptive Function”. The notion of a relation-e (relation in extension) so derived is called an operation, and of course all dyadic relation-e theorems rely ultimately on the comprehension axiom schema for relations in intension given at *12.11. But in attempting to give a general pattern of definition, *38 uses the odd-looking “x?y ” which lends itself to the misconception that is itself an operation sign. The informal summary makes matters worse, writing “E!(x?y)” which is ungrammatical. This paper argues that with P, R and S as relation-e variables and ?, ?, and ? as class variables, operations are comprehended by wffs such as “ P=x?y”, “?=???” and “P=R?S”. Relying on triadic relations-e, I explain how the sign ? can be entirely avoided using comprehension. Along the way, puzzling cases such as ? and ? are resolved. [Greek and other symbols do not repoduce here. See the first page of the paper for the correct abstract.--Ed.]
Медіація як альтернативний спосіб врегулювання конфліктів та інструмент державного управління
Authors: Чередніков Сергій 
Published: November 2022

Протягом усієї історії людства конфлікти були і є невід’ємною частиною його існування. Залежності від багатьох обставин вони можуть вести до самих різноманітних наслідків: від потужного поштовху до змін та розвитку - до руйнування держав та колосальних людських жертв. Переважна більшість соціально-політичних конфліктів вирішуються силовими методами, хоча це, безумовно, спричиняє дуже великі втрат ресурсів: людських, часових, фінансових тощо. Тому актуальним є питання пошуку альтернативних методів врегулювання конфліктів...
Ефективність прийняття рішень органами влади в нових умовах реагування на кризові ситуації
Authors: Черниш Вадим 
Published: November 2022

Пандемія коронавірусної хвороби виявила недосконалості систем публічного управління багатьох країн і Україна не стала виключенням. Перші особи держав, національні уряди зіштовхнулись з необхідністю масштабного кризового управління, що охоплювало багато сфер функціонування суспільства та передбачало запровадження нових форм реагування на надзвичайні ситуації, в тому числі і на міжнародному рівні...
Публічна влада в Україні в умовах пандемії COVID-19
Authors: Мануілова Катерина , Пурцхванідзе Ольга , Колеснікова Катерина 
Published: November 2022

Сьогодні можна з упевненістю стверджувати, що за чисельністю жертв, масштабами захворювання коронавірусною інфекцією, а також значним негативним впливом на соціально-економічну сферу всіх держав світу спалах пандемії COVID-19 є найбільшим і безпрецедентним викликом у перших двох декадах XXI століття. Багатьом людям довелося змінити своє «доковідне» життя й перейти на дистанційну форму роботи й освіти. Сьогодні у світі лишаються риторичними питання: Коли повернемся до традиційного «безкарантинного» повсякденного життя? або Повернімося ми до того життя, яке існувало до пандемії?..
Pengaruh Pandemi Covid Terahadap Penerimaan Pajak di Negara Indonesia pada Tahun 2020
Authors: Baitus Salamah  , Imahda Khoiri Furqon  
Published: November 2022

Pajak merupakan sumber utama penerimaan Negara yang menyumbang sekitar 70% dari seluruh penerimaan pajak. Tanpa pajak, sebagian besar kegiatan Negara akan sulit untuk dilaksanakan. Penggunaan pajak mulai dari belanja pegawai sampai dengan pembiayaan berbagai proyek pembangunan. Karena itu, pajak merupakan ujung tombak pembangunan sebuah Negara. Sehingga sudah sepantasnya ssbagai warga Negara yang baik untuk taat membayar pajak. Pemerintah Indonesia sudah memberikan kemudahan kepada masyarakat untuk membayar pajak.
Artikel ini akan membahas mengenai dampak dari pandemi covid. Pandemi covid yang melanda hampir semua Negara didunia termasuk Indonesia ini membawa dampak buruk yang sangat banyak. Seperti pembatalan penerbangan domestic dan internasional, menurunnya jumlah wisata asing yang berkunjung ke Indonesia, penurunan okupansi hotel, kehilangan sector layanan udara, kontraksi PMI Manufacturing Indonesia yang cukup dalam hingga 4,3 atau lebih rendah dibandingkan tahun lalu, meluasnya PHK menyebabkan angka pengangguran menambah, dampak inflasi sehingga merosotnya nilai tukar uang, turunnya daya beli masyarakat,berkurangnya investasi, berkurangnya ekspor dan impor. Hal tersebut juga mengakibatkan turunnya penghasilan masyarakat maupun perusahaan sehingga berdampak turunnya penerimaan dari pajak penghasilan.
Lag exponential synchronization of fractional-order complex-valued dynamical networks with multiple delays via adaptive control
Authors: Ding Dawei , Wang Ya , Hu Yongbing , Yang Zongli , Zhang Hongwei , Zhang Xu 
Published: November 2022

Abstract
In this paper, the lag exponential synchronization issue of fractional-order complex-valued dynamic networks with multiple delays is studied. Considering the uncertain factors in the networks, a system model with uncertain disturbance and coupling strength is established. In addition, in order to study the dynamic behavior of complex networks under different coupling delays, symmetric and un symmetric matrices are used to model the coupling systems, respectively. By using Lyapunov stability theorem and fractional-order theory, the criterion of lag exponential synchronization of complex networks via adaptive control are obtained. The result extends the single delay problem of fractional-order complex-valued systems to multiple delays. Finally, two examples of fractional-order complex-valued systems are given to verify the correctness of the theoretical derivation.
Intraabdominal hypertension and abdominal compartment syndrome in children and adolescents: results of a follow-up survey among pediatric intensivists
Authors: Wiegandt Paul , Jack Thomas , Gise Alexander , Seidemann Kathrin , Böhne Martin , Köditz Harald , Beerbaum Philipp , Sasse Michael , Kaussen Torsten 
Published: November 2022

AbstractBackground:Constantly elevated intra-abdominal pressure (IAH) can lead to abdominal compartment syndrome (ACS), which is associated with organ dysfunction and even multiorgan failure. Our 2010 survey revealed an inconsistent acceptance of definitions and guidelines among pediatric intensivists regarding the diagnosis and treatment of IAH and ACS in Germany. This is the first survey to assess the impact of the updated guidelines on pediatric intensive care units (PICU) after WSACS published those in 2013.Methods:We conducted a follow-up survey and sent 473 questionnaires to 328 German- speaking pediatric hospitals. We compared our findings regarding awareness, diagnostics and therapy of IAH and ACS with the results of our 2010 survey.Results:The response rate was 48% (n=156). The majority of respondents was from Germany (86%) and working in PICUs with mostly neonatal patients (53%). The number of participants who stated that IAH and ACS play a role in their clinical practice rose from 44% in 2010 to 56% in 2016. Similar to the 2010 investigations, only a few pediatric intensivists knew the correct WSACS definition of an IAH (4% vs 6%). Different from the previous study, the number of participants who correctly defined an ACS increased from 18% to 58% (p<0,001). The number of respondents measuring intra-abdominal pressure (IAP) increased from 20% to 43% (p<0,001). Decompressive laparotomies (DLs) were performed more frequently than in 2010 (36% vs. 19%, p<0,001), and the reported survival rate was higher when a DL was used (85%± 17% vs. 40± 34%).Conclusions: Our follow-up survey of pediatric intensivists showed an improvement in the awareness and knowledge of valid definitions of ACS. Moreover, there has been an increase in the number of physicians measuring IAP in patients. However, a significant number has still never diagnosed IAH/ACS, and more than half of the respondents have never measured IAP. This reinforces the suspicion that IAH and ACS are only slowly coming into the focus of pediatric intensivists in German-speaking pediatric hospitals. The goal should be to raise awareness of IAH and ACS through education and training and to establish diagnostic algorithms, especially for pediatric patients. The increased survival rate after conducting a prompt DL consolidates the impression that the probability of survival can be increased by timely surgical decompression in the case of full-blown ACS.
Community Health Teams: A Qualitative Study about the Factors influencing the Decision-Making Process for Resource Allocation
Authors: Natkin Lisa W. , Broek-Altenburg Eline van den , Benson Jamie S. , Atherly Adam 
Published: November 2022

Abstract
Background: The purpose of this study was to explore the contextual factors influencing how individual Community Health Teams make decisions about what services to offer and how to allocate their resources.
Methods: We conducted thirteen semi-structured interviews with Community Health Team (CHTs) leaders between January to March, 2021. We analyzed interviewees descriptions of their service offerings, resources allocation, and decision-making process to identify themes.
Results: Four major themes emerged from the interview data as contextual factors influencing community health team program managers’ decision-making process: commitment to offering high quality care coordination, Blueprint’s stable and flexible structure, use of data in priority setting, and leveraging community partnerships and local resources.
Conclusions: Community based CHTs with flexible funding allowed programs to tailor service offerings in response to community needs. It is important for teams to have access to community level data. Teams are cultivating and leveraging community partners to increase their care coordination capacity, which is focus of their work. CHTs are a model for leveraging community partnerships to increase service capacity and pubic engagement in health services for other states to replicate.
An insight investigation to the antiurolithic activity of Trachyspermum ammi using the in vitro and in vivo experiments
Authors: Khan Aslam , Gilani Anwarul-Hassan 
Published: November 2022

Abstract
The crude extract of Trachyspermum ammi seeds (Ta.Cr) was studied for its antiurolithic activity using the in vivo and in vitro experiments. In the in vivo experiments, Ta.Cr treatment showed a diuretic activity at the dose of 30 and 100 mg/kg and exhibited curative effect in male hyperoxaluric Wistar rats, which received 0.75% ethylene glycol (EG) in drinking water given for 3 weeks, with 1% ammonium chloride (AC) for initial three days. In the in vitro experiments, Ta.Cr delayed the slopes of nucleation and inhibited the calcium oxalate (CaOx) crystal aggregation in a concentration-dependent manner like that of Potassium citrate. Ta.Cr also inhibited DPPH free radicals like standard antioxidant drug butylated hydroxytoluene (BHT), and significantly reduced cell toxicity and LDH release in Madin-Darby canine kidney (MDCK) cells, exposed to oxalate (0.5 mM) and COM (66 µg/cm2) crystals. In isolated rabbit urinary bladder strips, Ta.Cr relaxed High K+ (80mM) and CCh (1 µM)-induced contractions, showing antispasmodic activity. The findings of this study suggest that the antiurolithic activity of crude extract of Trachyspermum ammi seeds may be mediated by a number of mechanisms, including a diuretic, an inhibitor of CaOx crystal aggregation, an antioxidant, renal epithelial cell protection, and an antispasmodic. Thus, showing therapeutic potential in urolithiasis, for which there is no viable non-invasive option in modern medicine.
Behavioural change interventions encouraging clinicians to reduce carbon emissions in clinical activity: A systematic review
Authors: Batcup Carys , Breth-Petersen Matilde , Dakin Thomas , Barratt Alexandra , McGain Forbes , Newell Ben , Pickles Kristen 
Published: November 2022

Abstract

Background
Clinical activity accounts for 70–80% of the carbon footprint of healthcare. A critical component of reducing emissions is shifting clinical behaviour towards reducing, avoiding, or replacing carbon-intensive healthcare. The objective of this systematic review was to find, map and assess behaviour change interventions that have been implemented in healthcare settings to encourage clinicians to reduce greenhouse gas emissions from their clinical activity.
Methods
Studies eligible for inclusion were those reporting on a behaviour change intervention to reduce carbon emissions via changes in healthcare workplace behaviour. Six databases were searched in November 2021 (updated February 2022). A pre-determined template was used to extract data from the studies, and risk of bias was assessed. The behaviour change techniques (BCTs) used in the interventions were coded using the BCT Taxonomy.
Results
Six full-text studies were included in this review, and 14 conference abstracts. All studies used a before-after intervention design. The majority were UK studies (n = 15), followed by US (n = 3) and Australia (n = 2). Of the full-text studies, four focused on reducing the emissions associated with anaesthesia, and two aimed at reducing unnecessary test ordering. Of the conference abstracts, 13 focused on anaesthetic gas usage, and one on respiratory inhalers. The most common BCTs used were social support, salience of consequences, restructuring the physical environment, prompts and cues, feedback on outcome of behaviour, and information about environmental consequences. All studies reported success of their interventions in reducing carbon emissions, prescribing, ordering, and financial costs; however, only two studies reported the magnitude and significance of their intervention’s success. All studies scored at least one item as unclear or at risk of bias.
Conclusion
Most interventions to date have targeted anaesthesia or pathology test ordering in hospital settings. Due to the diverse study outcomes and consequent inability to pool the results, this review is descriptive only, limiting our ability to conclude the effectiveness of interventions. Multiple BCTs were used in each study but these were not compared, evaluated, or used systematically. All studies lacked rigour in study design and measurement of outcomes.
Other
The study was registered on Prospero (ID number CRD42021272526).1
Evaluating the potential of a hybrid baffled reactor for simultaneous organic matter and nitrogen removal of dairy wastewater
Authors: Lucio Danilo S. G. , Dias Maria Eduarda S. , Ribeiro Rogers , Tommaso Giovana 
Published: November 2022

Abstract
This work designed and assessed the performance of a structured-bed hybrid baffled reactor (SBHBR) with anaerobic/anoxic chambers, treating different dairy wastewater. The anoxic chambers in SBHBR were exposed to intermittent aeration for the simultaneous removal of organic matter and total nitrogen (TN) under a low COD/TN ratio. The hydraulic retention time (HRT) in SBHBR was 48h, with 16.3h in the anoxic zone, where intermittent aeration was implemented, consisting of 60 minutes of aeration and 30 minutes without aeration. The COD/TN ratios tasted were 2.1 ± 0.6, 0.84 ± 0.5, and 0.35 ± 0.1 in the inlet of the anoxic chambers. The SBHBR provided COD removal efficiencies above 90% in all experimental stages. The relevant results achieved in this research regarding carbon and nitrogen removal efficiencies were obtained in stage III. The SBHBR achieved a TN removal efficiency of 82.3 ± 11.4% during this stage. The nitrification and denitrification efficiencies were 85.9 ± 17% and 85.2 ± 9%, respectively, resulting in the anoxic zone TN removal efficiency of 74.6 ± 14.7% with a C/N ratio of 0.35 ± 0.1. Stoichiometric calculations based on nitrogen removal and the C/N ratio required by the denitrification process were used to corroborate the activity of bacteria that perform the anammox pathways as their main mechanism.
Synthesis of three new macroacyclic Schiff base complexes and the investigation of their anticancer, antioxidant and antibacterial properties: theoretical and solid state structures
Authors: keypour Hassan , hajari saadat , yaghoobi fereshteh , rezaei mohammadtaher , farida seyed hamed moazzami , saadati masoud , Gable Robert 
Published: November 2022

AbstractThree symmetrical macroacyclic Schiff base complexes were prepared from a ligand derived from the condensation reaction of 1,4-bis(2-Aminophenyl)piperazine and salicylaldehyde (L) with Cu(II), Ni(II) and Co(II) perchlorates. The ligand and the Schiff base complexes were characterized by elemental analyses, FT-IR and mass spectrometry, with the structure of [CoL] being determined by a single crystal X-ray structural analysis. In this complex, the cobalt is in a distorted trigonal prismatic coordination environment, surrounded by the six donor atoms of the deprotonated hexadentate ligand. In order to compare the experimental and theoretical data and determine structure parameters in all complexes, Density Functional Theory (DFT) calculations at the B3lyp and BP86 levels with Def2-TZVP basis set have been carried out. NBO and QTAIM analyses have been used to describe the nature of M-O and M-N bonding in these complexes. The synthesized complexes were screened for their antioxidant activities using the DPPH free radical scavenging assay while their bactericidal activity was evaluated by the paper disc diffusion method against both Gram-negative and Gram-positive bacteria, revealing strong antioxidant activities and moderate effectiveness against all bacteria tested. The cytotoxicity of the metal complexes was also investigated against AGS (gastric) and A549 (lung) adenocarcinoma cells.
Stochastic Gradient Descent for Optimization of Nuclear Systems
Authors: Williams Austin , Walton Noah , Maryanski Austin , Bogetic Sandra , Hines Wes , Sobes Vladimir 
Published: November 2022

Abstract
The use of gradient descent methods for optimizing k-eigenvalue nuclear system has been shown to be useful in the past, but the k-eigenvalue gradients have proved challenging due to their stochastic nature and uncertainty. ADAM is a gradient descent method that accounts for gradients with a stochastic nature. This analysis uses challenge problems constructed to verify if ADAM is a suitable tool to optimize k-eigenvalue systems. ADAM is able to successfully optimize nuclear systems using the gradients of k-eigenvalue problems despite their stochastic nature and uncertainty.