bluuebunny/crossref_metadata_2025_split huggingface dataset:
Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L.
Authors: Menicucci Felicia , Marino Giovanni , Sillo Fabiano , Carli Andrea , dos Santos Nascimento Luana Beatriz , Detti Cassandra , Centritto Mauro , Brunetti Cecilia , Balestrini Raffaella Maria 
Published: February 2025

IntroductionPlant growth and metabolism can be optimized by manipulating light intensity and wavelength. Since the use of light-emitting diodes (LEDs) allows easy regulation of the light spectrum, LEDs technology is largely tested to produce high-quality food. Red leaf chicory is a horticultural plant of high commercial value, rich in vitamins, minerals and phytochemical compounds with bioprotective and antioxidant roles.MethodsCichorium intybus L. (Asteraceae family) seedlings of the cultivar Rossa di Treviso Precoce and Rossa di Treviso Tardiva were cultivated under blue and red LEDs for three to four weeks, whereas white LEDs, proving full visible light spectrum, were supplied as control. The leaf polyphenols were characterized and quantified by HPLC-DAD-Q-ToF analysis, the leaf chlorophyll content was measured using a handheld optical analyzer and the photosystem II efficiency was assessed with a porometer-fluorometer.ResultsThe PS II efficiency decreased in response to red LEDs treatment only. The highest levels of polyphenol and chlorophyll content were registered in response to blue LEDs exposure in both cultivars. The Rossa di Treviso Tardiva also exhibited a significant accumulation of polyphenols under red LEDs compared to white LEDs. The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. The leaf extracts of plants grown under red LEDs showed a prevalence of kaempferol 3-O-glucuronide, whereas a predominance of quercetin derivatives was found in response to white and blue LEDs. The comparison of the two cultivars revealed that the Rossa di Treviso Precoce was characterized by a higher content of polyphenols, independently of the type of LEDs.DiscussionSpecies-specific protocols are required for producing high-content nutrient vegetables. In our study, red LEDs induced a completely different leaf polyphenol composition than blue and white LEDs, pointing out that an accurate light spectrum selection is crucial for shaping plant metabolism. Blue LEDs improved the content of photosynthetic pigments and induced an accumulation of highly antioxidant polyphenols in both Rossa di Treviso Precoce and Tardiva C. intybus cultivars, emerging as a valuable tool for improving their nutraceutical content.
Mycorrhizal fungus BJ1, a new species of Tulasnella sp.: its biological characteristics and promoting effect on seed germination of Bletilla striata
Authors: Li Zhengmei , Ye Yueyu , Wang Xia , Peng Suyu , Chen Beibei , Li Shiqing , Chen Haimin , Yang Dongfeng , Jiang Fusheng , Zhang Chunchun , Li Meiya 
Published: February 2025

Mycorrhizal fungi have been shown to promote seed germination and seedling growth in Orchidaceae plants. In the present study, a mycorrhizal fungus designated as BJ1 was isolated from the roots of Bletilla striata (Thunb.) Reiehb.f. Fluorescence staining and morphological analysis revealed that this fungus exhibited characteristics highly similar to those of Tulasnella. Subsequently, the strain was confirmed as a new strain of Tulasnella through sequencing and phylogenetic analysis of four loci: the internal transcribed spacer region ITS1-ITS4 (ITS), ATP synthase (C14436), glutamate synthase (C4102), and ATP deconjugase (C3304). Additionally, we investigated the in vitro biological activity of strain BJ1 and its effects on germination and growth of B. striata seeds. The results indicated that BJ1 is capable of producing plant cell-degrading enzymes, including pectinase and protease. Furthermore, it demonstrates an ability to solubilize inorganic phosphorus and synthesize indoleacetic acid (IAA). Nevertheless, it does not exhibit laccase activity or possess the capacity to produce siderophores, nor can it solubilize organic phosphorus. Microscopic observations revealed that strain BJ1 mainly colonizes the base of the B. striata protocorm, thereby enhancing seed germination, growth, and expansion. Notably, by the fourth week of germination, 74.23% of seeds in the symbiotic group had developed to stage 5, a significantly higher proportion compared to 50.43% in the non-symbiotic group. Additionally, the length, width, and fresh weight of seeds in the symbiotic group were 2.2 times, 1.8 times, and 3.7 times greater than those in the non-symbiotic group, respectively. Furthermore, by adding L-tryptophan as a substrate during co-cultivation with BJ1, there was a significant enhancement in IAA synthesis capability; this also led to a marked acceleration in the symbiotic germination process of B. striata seeds. These results suggest that strain BJ1 holds significant potential for application in the artificial propagation of B. striata seedlings. It can enhance propagation efficiency and improve seedling quality, thereby playing a crucial role in the conservation and sustainable development of germplasm resources of endangered orchids.
How physical exercise enhances life satisfaction in Chinese senior college students: mediating roles of self-efficacy and resilience
Authors: Yu Huasen , Li Xuening , Yu Xin , Fusheng Liang , Li Liqiang , Yang Yuhang , Wu Jin 
Published: February 2025

ObjectiveThis study explored the relationship between physical exercise and life satisfaction among senior college students by focusing on the mediating roles of self-efficacy and resilience, thereby providing theoretical support for the mental health benefits of physical exercise for senior students.MethodsA survey was conducted with 600 senior students from 10 universities using the physical exercise rating, life satisfaction, self-efficacy, and resilience scales. Data analysis was performed using SPSS 23.0 for descriptive statistics, correlation analysis, and reliability and validity assessments. In addition, AMOS software (version 24.0) was used to construct a structural equation model to test the hypothesized pathways and the effects of potential mediating variables.ResultsThere were significant positive correlations among the variables of physical exercise, life satisfaction, self-efficacy, and resilience (r = 0.11–0.62, all p &lt; 0.01). The structural equation model revealed that resilience fully mediated the relationship between physical exercise and life satisfaction among senior students (95% CI: 0.105–0.243), while self-efficacy did not mediate this relationship (β = 0.02, p = 0.77). However, a chain mediating effect involving self-efficacy and resilience was observed between physical exercise and life satisfaction (95% CI: 0.127–0.235).ConclusionEnhanced physical exercise can improve self-efficacy and resilience among senior college students, thereby increasing their life satisfaction.
Comparative efficacy of traditional non-pharmacological add-on treatments in patients with stable chronic obstructive pulmonary disease: a systematic review and network meta-analysis
Authors: Roh Ji-Ae , Leem Jungtae , Lee Beom-Joon , Kim Kwan-Il , Jung Hee-Jae 
Published: February 2025

Chronic obstructive pulmonary disease (COPD) is a major global public health concern. In this study, we examined the comparative efficacy of non-pharmacological interventions within East Asian traditional medicine (EATM-NPI) for enhancing pulmonary function and exercise capacity in patients with stable COPD. A thorough search of electronic databases conducted until May 22, 2022, identified studies employing EATM-NPI in such patients. The evaluation focused on the impact adjunctive therapies on pulmonary function (forced expiratory volume in 1 s [FEV1]) and exercise capacity (6-min walking distance [6MWD]). The qualitative assessment encompassed 142 studies, with 133 studies included in one of three network meta-analyses. Participants, aged 49–76 years, ranged from 9 to 139 per group, predominantly from China (87.7% of studies). Overall study quality was generally low, and reported adverse events were mild. Notably, moxibustion and qigong adjunctive therapies demonstrated significant improvements in FEV1 (L) and FEV1 (%). Additionally, chuna, acupuncture, qigong and moxibustion adjunctive therapies were associated with significant improvements in 6MWD. In conclusion, EATM-NPI adjunctive therapy, when combined with standard pharmacological treatment, exhibited effects on pulmonary function and exercise capacity in patients with COPD.Systematic review registration: The protocol was registered with PROSPERO (CRD42023389431), https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023389431.
Time to initiation of antiresorptive agents in multiple myeloma to reduce skeletal related events
Authors: Bhasin Amman , Binder Adam Finn , Damron Leland , Majeed Amry , Barsouk Adam , Hughes Kelly , Raj Niketa , Abdulkareem Abdullateef O. , Zhan Tingting , Polu Divya , Gundepalli Sai , Devarakonda Srinivas 
Published: February 2025

PurposeCurrent treatment guidelines strongly support the use of antiresorptive therapy in patients with newly diagnosed multiple myeloma (NDMM) with the goal of preventing skeletal related events (SRE). Despite these concrete, data-driven recommendations, the impact of delays in antiresorptive initiation in NDMM patients is understudied. Through a multicenter retrospective study, we examined the impact of delays in antiresorptive initiation on the rates of SREs. We furthered our exploration of this topic in a separate retrospective analysis with a focus on reasons for delays in antiresorptive therapy initiation.MethodsElectronic health records from two large academic institutions were used to identify patients with NDMM between July 1, 2016, and June 30, 2019. Exclusion criteria included patients with previous antiresorptive use and patients never prescribed antiresorptives. Time to antiresorptive initiation and its subsequent impact on the rate of SREs was analyzed using hazard ratios. A follow up, single-center retrospective study was conducted using EHR data with an emphasis on the identification of barriers to antiresorptive initiation. Here, descriptive, and inferential statistics were used to identify variables that have a statistically significant impact on antiresorptive initiation.ResultsA total of 759 patients with newly diagnosed MM met inclusion criteria for our multicenter study. Our study found that a delay in initiation of anti-resorptive therapy of greater than 31 days from diagnosis resulted in an increased risk for SRE with a hazard ratio of 1.654 (95% CI: 1.054-2.598; p-value = 0.029). In our follow up study, a total of 45.6% of patients with newly diagnosed MM were prescribed antiresorptive therapy, while 59% of patients with identified lytic lesions on screening imaging received anti-resorptive therapy. Statistically insignificant differences were observed in the time to initiation of anti-resorptive therapy based on health insurance. Variables such as race and gender were not found to have a statistically significant relationship with delays in antiresorptive initiation.ConclusionsPatients with NDMM should be initiated on antiresorptive therapy without delay to minimize the rates of SREs, and clinicians should be diligent in anticipating delays in initiation such as need for dental clearance and renal disease.
Case Report: Repetitive peripheral magnetic stimulation and task-oriented training improve motor function in chronic severe post-stroke paralysis
Authors: Yamamoto Satoshi , Aoyama Toshiyuki , Ishii Daisuke , Ishibashi Kiyoshige , Kohno Yutaka 
Published: February 2025

BackgroundSevere upper-limb motor paralysis following chronic stroke presents a significant rehabilitation challenge, often with limited recovery. This case study explores the effects of repetitive peripheral magnetic stimulation (rPMS) combined with task-oriented training on motor recovery in a patient with chronic stroke and severe upper-limb impairment.MethodsA 50-year-old male with right upper-limb paralysis post-hemorrhagic stroke underwent a 2-week intervention comprising 12 sessions of rPMS targeting the elbow and wrist extensors, combined with task-oriented training. Motor function was assessed using the Fugl-Meyer Assessment (FMA), kinematic analysis, Motor Activity Log (MAL), and electromyographic (EMG) analysis of wrist flexion-extension movements.ResultsThe intervention resulted in a clinically meaningful increase in motor function, reflected in improved FMA scores and greater elbow extension during kinematic analysis. EMG analysis demonstrated reduced co-contractions of wrist flexors and extensors, indicating improved muscle coordination. Despite these gains, recovery of distal voluntary movements, such as wrist dorsiflexion and finger extension, remained limited. As assessed by MAL, upper-limb usage in daily activities showed minor improvements; however, qualitative reports indicated functional gains, including the ability to hold a bottle and assist in closing a car door.ConclusionrPMS combined with task-oriented training shows promise in enhancing motor function in patients with chronic stroke combined with severe upper-limb paralysis, particularly in proximal muscles. Further research involving control groups and objective measures of upper-limb use is necessary to validate these findings and refine intervention protocols.
Adenovirus Interstitial Nephritis post-Kidney Transplant
Authors: Monteiro Cutrim Ézio Arthur , Garcia Campos Marcos Adriano , Strand Eleanor , Monteiro Cutrim Érico Murilo , Sodré Andressa Monteiro , Carvalho de Araújo Emmy Marjorie , Barros de Sousa Pedro Manuel , Alves Ferreira Teresa Cristina , Wagner de Castro Lima Santos Daniel , de Almeida Araújo Stanley , Filho Natalino Salgado , Barros Silva Gyl Eanes 
Published: February 2025

Background:
Post-kidney transplant adenovirus nephritis is a condition with potential for acute allograft dysfunction, and evidence on its management is scarce.

Methods:
The present study is an original case series based on kidney biopsy of seven patients obtained at a health center specialized in kidney pathology from 2009 to 2023. We also performed a non-systematic literature review on cases described in the literature.

Results:
Kidney biopsy was used to define the diagnosis of all patients. The average time to diagnosis after transplantation was 32.9 months. The most prevalent symptoms were fever, macroscopic hematuria, and dysuria. The glomerular filtration rate (GFR) reduced on average four times in relation to the baseline GFR. The main findings of kidney biopsy were acute tubular necrosis (100%), necrotizing granulomatous interstitial nephritis (100%) and viral inclusions (100%). The therapies used were human immunoglobulins, antivirals, and reduction of immunosuppression. The clinical course was favorable in six of the seven patients. Our literature review found 44 cases of adenovirus interstitial nephritis, and the outcome was favorable in the majority of reported cases.

Conclusions:
Adenovirus interstitial nephritis is a rare condition, but with important implications for kidney transplant recipients. Kidney biopsy plays a very important role in confirmation. This study fills gaps in the current literature on adenovirus interstitial nephritis and contributes to the understanding of this potential complication in the follow-up of kidney transplant recipients.
Analysis of Cardiovascular and Cerebrovascular Prognosis and Risk Factors in Patients with Primary Membranous Nephropathy
Authors: Ye Nan , Yang Lei , Wang Guoqin , Cheng Wenrong , Xie Bing , Dong Hongrui , Kong Lingqiang , Zhao Xiaoyi , Geng Yanqiu , Cheng Hong 
Published: February 2025

Background:
This study investigated risk factors and possible mechanisms of arterial and venous thromboembolic events in patients with pMN.

Methods:
Patients with pMN confirmed by renal biopsy from June 1, 2010 to March 3, 2023 were included, and the study outcome was set as a composite endpoint of acute coronary syndrome, heart failure, cerebral infarction, arrhythmia, pulmonary embolism, deep venous thrombosis and all-cause mortality.

Results:
A total of 433 pMN patients with complete data were included, with a median follow-up time of 73 (45.5–101.6) months and a composite endpoint rate of 10.2%. We divided all patients with events into early event group (events occurring in the first 2 years after renal biopsy) and late event group (events occurring after 2 years after renal biopsy) according to the time of event. It showed a lower serum albumin and a higher baseline value of serum PLA2R antibody titer and mean value of each follow-up in the early event group compared with the late event group. Cox proportional hazards model showed that after adjusting for confounding factors, in addition to older age, history of deep vein thrombosis and higher urinary protein, higher baseline serum PLA2R antibody titers (OR 1.034, 95% CI 1.006 -1.063, P = 0.015), and high hsCRP level (OR 1.049, 95% CI 1.002 -1.098, P = 0.041), renal pathology with segmental sclerotic lesions (OR3.480, 95% CI 1.338 –9.050, P = 0.011) were also independent risk factors for the occurrence of endpoint events. The results also showed that baseline serum IL-6 levels were significantly higher in the event group compared with the non-event group (4.25 pg/ml vs. 3.21 pg/ml), and the difference was statistically significant (P = 0.009).

Conclusions:
In the early event group, higher serum PLA2R antibody and renal pathology with segmental sclerosis lesions may affect the occurrence of cardiovascular and cerebrovascular events and venous thrombotic events. The inflammatory system may play a role in this relationship.
Креативный учет: сущность и оценка в ходе судебно-бухгалтерской экспертизы
Authors: Пащенко Т.В. , Халилова Д.Р. 
Published: February 2025

Важным условием успешного развития финансово-хозяйственной деятельности организации является ведение бухгалтерского учета в соответствии с законодательством и формирование достоверных показателей отчетности, которые служат основой принятия управленческих решений. В последнее время в современном бухгалтерском учете нередко стали использовать понятие «креативный» учет, сущность которого не до конца установлена как с научной, так и с методической позиции. Всё это ещё больше усложняет задачу бухгалтера-эксперта, когда нужно на основе данных бухгалтерского учета установить какие-либо факты о деятельности организации. Целью данной работы является установление причин возникновения и развития креативного учета, выделение его особенностей, выявление проблемных сторон и внесение предложений по решению спорных вопросов в ходе производства судебно-бухгалтерских экспертиз. В результате исследования сделан вывод о том, как можно использовать позитивные и негативные проявления креативного учёта и оценивать их в ходе судебно-бухгалтерской экспертизы.
An important condition for the successful development of the financial and economic activities of an organization is accounting in accordance with the legislation and the formation of reliable reporting indicators for management decisions. Recently, in modern accounting, the concept of «creative» accounting has often begun to be used, the essence of which is not fully clarified. The purpose of this work is to disclose the essence of creative accounting, identify problematic parties and make proposals for resolving controversial issues. As a result of the research, it was concluded that it is worthwhile to rationally use the positive aspects of creative accounting and limit its negative manifestations.
Обзор финансового результата деятельности организации
Authors: Рознина Н.В. , Карпова М.В. , Лапина Е.Н. 
Published: February 2025

Актуальность исследуемого вопроса обусловлена тем, что финансовый результат деятельности хозяйствующих субъектов - важнейший элемент рыночной экономики [15]. Роль прибыли хозяйствующих субъектов сложно переоценить, так как она является конечным финансовым результатом организации и выступает источником пополнения её финансовых ресурсов [14]. Получаемая прибыль позволяет хозяйствующим субъектам осуществлять расширенное воспроизводство и удовлетворять социальные и материальные потребности учредителей и работников [7]. Посредством прибыли выполняются обязательства хозяйствующих субъектов перед бюджетом, внебюджетными фондами, кредитными организациями, иными учреждениями. В работе проведена оценка состава и структуры доходов и расходов АО «НПО «Курганприбор», проанализирована динамика показателей прибыли и рентабельности. Проведён операционный анализ. Предложены и экономически обоснованы мероприятия по повышению уровня финансовых результатов организации.
The relevance of the issue is due to the fact that the financial result of economic entities is an important element of the market economy. The role of profit of economic entities is difficult to overestimate, since it is the final financial result of the organization's activities and acts as a source of replenishment of its financial resources. The resulting profit allows economic entities to carry out expanded reproduction and meet the social and material needs of founders and employees. At the expense of profit, the obligations of economic entities to the budget, extra-budgetary funds, credit organizations and other institutions are fulfilled. The article assesses the composition and structure of revenues and expenses of JSC " NPO "Kurganpribor", analyzes the dynamics of profit and profitability indicators. An operational analysis was carried out. Proposed and economically justified measures to improve the level of financial results of the organization.
Экономическое обоснование возделывания льна в Курганской области
Authors: Дуничева С.Г. , Карпова М.В. , Рознина Н.В. 
Published: February 2025

В Курганской области традиционным является возделывание зерновых культур, но рыночные отношения диктуют применение смешанного возделывания, например, введение льна в севооборот. Льноводство считается доходной отраслью, хотя при этом остаётся достаточно трудоёмкой. В Курганской области площади, занимаемые льном, увеличились с 2750 га в 2012 году до 87374 га в 2020 году, при этом масличный лён занимает в структуре 84364,1 га или 96,6%, большая его часть приходится на сорт Северный. Анализ экономической эффективности получения семян различных сортов льна показал, что условно чистый доход колеблется от 35965 до 37345 рублей и окупаемость затрат в вариантах опыта выросла с 2,60 до 4,61 по сравнению с контролем, что указывает на доходность данной отрасли производства.
In the Kurgan region, grain cultivation is traditional, but market relations dictate the use of mixed cultivation, for example, the introduction of flax in crop rotation. Flax growing is considered a profitable industry, although it remains quite labor-intensive. In the Kurgan region, the area occupied by flax increased from 2,750 hectares in 2012 to 87,374 hectares in 2020, while oilseed flax occupies 84,364. 1 hectares or 96.6%, most of it falls on the Northern variety. An analysis of the economic efficiency of obtaining seeds of various flax varieties showed that the conditional net income ranges from 35965 to 37345 rubles and the cost recovery in the experimental variants increased from 2.60 to 4.61 compared to the control, which indicates the profitability of this industry.
Особенности бухгалтерского учета готовой продукции в сельскохозяйственной организации
Authors: Калугина О.А. , Никулина С.Н. , Гривас Н.В. 
Published: February 2025

Бухгалтерский учет - это сложная информационная система, Важная часть системы - учет готовой продукции. В данной статье на примере конкретной организации агропромышленного комплекса рассматриваются особенности бухгалтерского учета готовой продукции. Предлагаются направления по совершенствованию учета данного объекта исследования.
Accounting is a complex information system; an important part of the system is the accounting of finished products. In this article, on the example of a specific organization of the agro-industrial complex, the features of accounting for finished products are considered. Directions for improving the accounting of this object of research are proposed.