bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamic wake analysis of a wind turbine providing frequency support services
Authors: Singh Narender , De Kooning Jeroen D. M. , Vandevelde Lieven 
Published: April 2022

AbstractThe participation of wind farms in providing ancillary services is an asset for the power system and one way to maintain a strong grid with the increasing penetration of renewable energy sources. Research has shown this to be feasible for wind farms by using efficient prediction and sophisticated control systems. In some parts of the world, strict grid codes are already being implemented that require wind farms to provide ancillary services. Moreover, the primary reserve market in Europe is moving towards shorter procurement periods, providing wind farms an opportunity to more efficiently optimise their resources based on short term forecasts. It can however be challenging for the wind farms to efficiently participate in grid frequency support services, especially for primary reserve services. The reason behind this is the requirement of quick activation and deactivation of power reserve margin for services such as Frequency Containment Reserve (FCR) and Fast Frequency Response (FFR). A full activation of the contracted reserve is required within seconds of a grid frequency dip. A sudden change in wind turbine dynamics is expected to have an impact on the wake behind the wind turbine. The wake effect within a wind farm is taken into thorough consideration in its design process. The effect on the wake due to the wind turbines participating in fast response ancillary services however, remains unexplored. This is a matter of greater concern for wind farms with a high capacity density. To this end, the main contribution of this article is to observe the effect of ancillary service based control system on the wake effect of a wind turbine. Additionally, the capability of developed wind turbines controllers to follow primary reserve services are also tested. FFR and FCR services are tested for a range of frequency designs, these include both synthetic and actual grid frequencies. The synthetic frequency profiles are designed to replicate both fast and slow frequency variations in order to analyse the impact on wake behaviour. The simulations are performed for low and high wind speed including constant as well as turbulent winds.
Pars interarticularis repair using pedicle screws and laminar hooks fixation technique in patients with symptomatic lumbar spondylolysis
Authors: Zayan Mohammed , Hussien Mohammed Ali , El Zahlawy Hany 
Published: April 2022

Study Design: Prospective case series. Purpose: To assess the outcomes of pars repair surgery using pedicle screws and laminar hooks. Methods: This study was conducted on 22 patients with symptomatic lumbar spondylolysis. Curettage of the fibrocartilage in the defect and drilling of the sclerotic bone ends were done, followed by impaction of cancellous bone graft. Pedicle screws were inserted bilaterally in the corresponding pedicles and connected to a laminar hook via rods (screw-rod-hook fixation). The intensity of back pain and the functional outcome were assessed using the visual analog scale (VAS) and the Oswestry disability index (ODI). Plain radiographs were performed immediately postoperatively and after 3 and 6 months. CT scan was done at the final follow-up to assess pars healing. The mean follow-up period was 27 months. Results: The mean preoperative VAS and ODI were 7.4 ± 0.8 and 64.8 ± 6.7, which improved to 2.4 ± 0.8 and 20 ± 6 respectively at the final follow-up (P < 0.001). Healing of the defect was found in 19 patients at the final follow-up. Non-fusion with graft resorption was noticed in the remaining 3 cases (13.6%). However, postoperative VAS and ODI values improved even in the radiologically non-fused patients. Level of evidence: Therapeutic study, Level IV. Conclusion: Pars repair using pedicle screws and laminar hooks is a relatively simple yet effective procedure.
The correlation between clinical and radiological severity of osteoarthritis of the knee
Authors: Steenkamp Wynand , Rachuene Pududu Archie , Dey Roopam , Mzayiya Nkosiphendule Lindani , Ramasuvha Brian Emmanuel 
Published: April 2022

Introduction: Primary osteoarthritis (OA) is a common cause of knee pain. Appropriate management of knee OA is based on clinical and radiological findings. Pain, deformity, and functional impairments are major clinical factors considered along with radiological findings when making management decisions. Differences in management strategies might exist due to clinical and radiological factors. This study aims at finding possible associations between clinical and radiological observations.Methods: A prospective cross-sectional study of 52 patients with primary osteoarthritis of the knee managed conservatively at a tertiary hospital arthroplasty clinic was conducted for three months. English speaking patients with primary OA were identified and included in this study. Pain and functional impairment were assessed using Wong-Baker Faces pain scale, The Knee Society Score (KSS), and Western Ontario and McMaster Osteoarthritis Index (WOMAC). The Body Mass Index (BMI) of all participants was measured. Standard two views plain radiographs were used for radiographic grading of the OA. Anonymized radiographs were presented to two senior consultant orthopaedic surgeons who graded the OA using Kellgren and Lawrence (KL) and Ahlbäck classification systems. The severity of the functional impairment and pain score was then compared to the radiological grading.Results: The average age of our participants was 63 ± 9 years. Their average BMI was 34.9 ± 8.4 kg/m2, median self-reported pain, total WOMAC, and pain WOMAC scores were 8, 60, and 13, respectively. We observed no significant correlation between BMI and pain scores. Inter-rater reliability for KL and Ahlbäck grading was strong. There was no significant correlation between WOMAC scores and the radiological grades.Conclusion: There was no correlation between pain and functional scores, patient factors and radiological severity of OA of the knee.
Radiation doses from low-dose CT scans in SPECT/CT and PET/CT examinations: A survey in Germany
Authors: Rinscheid Andreas , Janzen Tilman , Alikhani Babak , Beer Ambros J. , Braune Anja , Eberhardt Nina , Fechner Diana , Förster Stefan , Freesmeyer Martin , Furth Christian , Grunert Michael , Hellwig Dirk , Costa Pedro Fragoso , Kühnel Christian , Lange Catharina , Linke Rainer , Razlaw Natalia , Sack Tobias , Schmidt Daniel , Schütze Christina , Starke Alexander , Tondera Liane , Wengenmair Hermann , Zöphel Klaus , Burchert Wolfgang , Lapa Constantin 
Published: April 2022

Abstract
Aim Recently, dose reference levels (DRLs) have been defined in Germany for auxiliary low-dose CT scans in hybrid SPECT/CT and PET/CT examinations, based on data from 2016/17. Here, another survey from 2020 was evaluated and compared with the new DRLs as well as with similar surveys from foreign countries.
Methods The survey, which had already been conducted in the Nordic countries, queried for various examinations including the following values: patient weight and height, volume CT dose index (CTDIvol), dose length product (DLP). For each examination, statistical parameters such as the third quartile (Q3) were determined from all submitted CTDIvol and DLP values. Additionally, for examinations comprising datasets from at least 10 systems, the third quartile (Q3-Med) of the respective median values of each system was calculated. Q3 and Q3-Med were compared with the newly published DRLs from Germany and values from similar studies from other countries.
Results Data from 15 SPECT/CT and 13 PET/CT systems from 15 nuclear medicine departments were collected. For the following examinations datasets from more than 10 systems were submitted: SPECT lung VQ, SPECT bone, SPECT&PET cardiac, PET brain, PET oncology. Especially for examinations of the thorax and heart, the new DRLs are very strict compared to this study. The CTDIvol values for examinations of the head were lower in this study than the DRLs prescribe now.
Conclusions For certain examination types, there is a need for dose optimization at some clinics and devices in order to take into account the new DRLs in Germany in the future.
Validity and Reliability of a New Method to Measure Cervical
Proprioception
Authors: Köseoğlu Aygul , Coşkunsu Dilber Karagözoğlu , Mutlu Ebru Kaya 
Published: April 2022

Abstract
Objective An accurate and reliable measurement of proprioception is
important in the evaluation of the cervical. The aim of this study is to
investigate the validity and reliability of a new method using Horizontal Plane
Target Platform (HPTP) to assess Head Repositioning Accuracy (HRA) for Cervical
Proprioception (CP).
Methods HRA values of 86 healthy volunteers
(21.01±2.16 yrs.) were measured through AOS PropPoint laser
apparatus device on HPTP, Frontal Plane Target Platform (FPTP), and also CROM
device to assess test-retest reliability and validity.
Results The test-retest measurements of HPTP reliability was
(ICCleft=0.69, ICCright=0.74;
SEMleft=0.28, SEMright=0.36;
MDCleft=1.85, MDCright=2.02
95%CI) were moderate for both side. Correlation with the CROM device
results was moderate for both side (r=0.75 for left size, r=0.83
for right side), and the absolute values demonstrate concordance between results
using the Bland-Altman method.
Conclusions HRA measurements performed with a laser apparatus on HPTP
which we developed can be used as an alternative method in CP evaluation.
Radiosynthesis and Tumor MicroPET/CT Imaging of 18F-Fluoro­ethoxylerianin, an 18F-Labeled Erianin Analogue
Authors: Nie Hui , Wang Nian , Huang Jinwen , Wang Mingwei , Wu Fanhong , Ni Zhuang , Xue Kangyan , Song Lixing 
Published: April 2022

AbstractErianin is an active constituent of Dendrobium candidum. In this work, 18F-fluoroethoxylerianin ([18F]FEE), a 18F-Labeled erianin analogue, was designed and synthesized to evaluate the properties of erianin and related analogues by in vivo PET imaging. The initial product was separated and purified by liquid-phase separation module Explora LC and simple homemade solid-phase extraction, and high purity [18F]FEE was finally obtained. The radiochemical purity of [18F]FEE was determined by Radio-TLC and Radio-HPLC. [18F]FEE showed good stability in normal saline and serum, and could be quickly eliminated from mice. Cell experiments, biological distribution, and small-animal PET/CT further showed that [18F]FEE had a high uptake rate in HepG2 tumor cells, and showed good imaging ability in a HepG2 tumor model. The results of this study indicate that the synthesized 18F-labeled erianin analogue is an effective new probe for positron emission tomography (PET) imaging of HepG2 hepatocellular carcinoma, which provides an intuitive and reliable theoretical basis for the development of erianin as an anticancer drug.
Endoscopic retrograde appendicitis therapy for acute appendicitis: a systematic review and meta-analysis
Authors: Dhindsa Banreet , Naga Yassin , Praus Alexander , Saghir Syed Mohsin , Mashiana Harmeet , Ramai Daryl , Chandan Saurabh , Sayles Harlan , Dhaliwal Amaninder , Bhat Ishfaq , Singh Shailender , Adler Douglas 
Published: April 2022

Abstract
Background and study aims Endoscopic retrograde appendicitis therapy (ERAT) is an endoscopic procedure for management of patients with acute appendicitis (AA). In addition to being minimally invasive, it has the added advantages of preservation of appendix and simultaneous inspection of colon. We performed a systematic review and meta-analysis on ERAT in patients with AA.
Methods We conducted a comprehensive search of multiple electronic databases (from inception through January 2022) to identify studies reporting ERAT in AA. The primary outcome was to evaluate the overall clinical and technical success of ERAT. The secondary outcome was to study the total and individual adverse events (AEs). The meta-analysis was performed using Der Simonian and Laird random effect model.
Results Seven studies reporting on 298 patients were included. The majority of the patient population was male (55.3 %), with mean age of 31 ± 12.39 years. The pooled technical success rate was 99.36 % (95 % CI 97.61–100, I2 = 0) and the pooled clinical success rate was 99.29 % (95 % CI 97.48–100, I2 = 0). The pooled AE rate was 0.19 % (95 % CI 0–1.55, I2 = 0). The most common AE was perforation with 0.19 % (95 % CI 0–1.55, I2 = 0). The recurrence rate was 6.01 % (95 % CI 2.9–9.93, I2 = 20.10). Average length of procedure was 41.1 ± 7.16 min. Low heterogeneity was noted in in our meta-analysis.
Conclusions ERAT is a safe procedure with high rates of clinical and technical success in patients with AA. Further randomized controlled trials should be performed to assess the utility of ERAT in AA as compared to laparoscopic appendectomy.
Ultrasound of Median Nerve in the Diagnosis of Carpal Tunnel Syndrome—Correlation with Electrophysiological Studies
Authors: Kanagasabai K. 
Published: April 2022

AbstractCarpal tunnel syndrome (CTS) is the most common entrapment neuropathy caused by impairment of the median nerve due to compression as it passes through the carpal tunnel.The current gold standard in diagnosing CTS and nerve damage is by electrophysiological nerve conduction study (NCS). However, 10 to 25% of NCS results are falsely negative. Moreover, NCS remains an expensive and time-consuming procedure for patients. Ultrasonography serves as a real-time, well-tolerated, portable, and noninvasive tool for assessing the carpal tunnel.This study aims to assess the role of high-frequency ultrasound of the median nerve at the wrist in evaluating CTS and correlate with NCS to determine whether sonography can be used as an alternative to NCS in diagnosing and grading CTS.
The Non-motor Symptoms, Disability Progression, and Survival Analysis of Atypical Parkinsonism: Case Series from Eastern India and Brief Review of Literature
Authors: Pani Tapas , Nayak Soumyadarshan 
Published: April 2022

AbstractObjective The objectives of this study are (1) to describe the non-motor profile, the motor disability progression, and survival analysis of atypical parkinsonism in a tertiary care hospital of eastern India and (2) to elucidate the neurocircuitry and the putative substrates responsible for non-motor manifestations.Methods In this prospective observational study, patients were diagnosed based on Consensus Criteria for Progressive Supranuclear Palsy (PSP), The Fourth Consensus Report of the Dementia with Lewy Body (DLBD) Consortium 2017, The Autonomic Neuroscience 2018 Criteria for Multiple System Atrophy (MSA), and Armstrong 2013 Criteria for Corticobasal Degeneration (CBD). Disease severity was assessed at baseline and 6 months of follow-up using the Unified Parkinson's Disease Rating Scales (UPDRS). For PSP and MSA, the PSP-Clinical Deficits Scale (PSP-CDS) and the Unified MSA Rating Scale (UMSARS), respectively, were used. Cox regression analysis and the hazard ratio were calculated.Results Out of 27 patients, the diagnosis was probable PSP in 12, probable MSA in 7, probable CBD in 5, and probable DLBD in 3. Non-motor symptoms were highly prevalent across all subtypes. Motor disability progression as assessed by UPDRS parts 2 and 3 showed significant deterioration over 6-month follow-up across all groups (p < 0.05). Disease progression assessed by PSP-CDS and UMSARS over 6 months was significant (p < 0.05). One PSP and two MSA patients died during a 6-month follow-up period. The hazard ratio in MSA was 3.5 (95% confidence interval: 0.31–0.38) withp = 0.306.Conclusion Atypical parkinsonian disorders are rare, and usually more severe than idiopathic parkinsonism. As no definitive treatment is available, symptomatic management involving a multidisciplinary team approach must be prioritized.
Is Thalamic Lesion a Contributing Factor for Inappropriate Sexual Behavior in Older Adults with Cognitive Impairment?
Authors: Mukku Shiva Shanker Reddy , Jagtap Namrata , Muliyala Krishna Prasad , Sivakumar P. T. , Sinha Preeti , Mangalore Sandhya , Varghese Mathew 
Published: April 2022

Abstract
Thalamus is a group of nuclei located deep inside the brain, well known for its sensory and cognitive functions. However, its role in the reward and behavior regulation is less explored. In this case series, we have presented four cases with inappropriate sexual behaviors (ISB) that are temporally related to thalamic infarction. We have discussed about the limbic part of thalamus and its extensive connections with other regions in regulating sexual behaviors. Although in all the four cases described there was underlying cognitive impairment that can itself increase the risk of ISB, there was potential contributing role of thalamic lesions.
Improving Audibility with Nonlinear Amplification for Listeners with High-Frequency Loss
Authors: Souza Pamela E. , Bishop Robbi D. 
Published: April 2022

AbstractIn contrast to fitting strategies for linear amplification that have been frequently refined for listeners with different degrees of hearing loss, we know relatively little about the effects of nonlinear amplification for differing audiometric configurations. The purpose of the current study was to determine whether increases in audibility with nonlinear amplification improved speech recognition to a comparable degree for listeners with sloping sensorineural loss as for a comparison group of listeners with flat sensorineural loss. Consonant recognition was examined as a function of audibility with wide dynamic range compression amplification and with linear amplification. For linearly amplified speech, listeners with flat and sloping loss showed similar improvements in recognition given the same increases in audibility. Results for nonlinearly amplified speech indicated that the listeners with flat loss showed a greater rate of improvement as audibility increases than the listeners with sloping loss. This difference is largely due to superior performance by the listeners with sloping loss for low-audibility speech in comparison to equivalent group performance for high-audibility speech.
Abbreviations: AAI = Aided Audibility Index, LDL = loudness discomfort level, MCR = modified compression ratio, VCV = vowel-consonant-vowel, WDRC = wide dynamic range compression
An integrative skeletal and paleogenomic analysis of stature variation suggests relatively reduced health for early European farmers
Authors: Marciniak Stephanie , Bergey Christina M. , Silva Ana Maria , Hałuszko Agata , Furmanek Mirosław , Veselka Barbara , Velemínský Petr , Vercellotti Giuseppe , Wahl Joachim , Zariņa Gunita , Longhi Cristina , Kolář Jan , Garrido-Pena Rafael , Flores-Fernández Raúl , Herrero-Corral Ana M. , Simalcsik Angela , Müller Werner , Sheridan Alison , Miliauskienė Žydrūnė , Jankauskas Rimantas , Moiseyev Vyacheslav , Köhler Kitti , Király Ágnes , Gamarra Beatriz , Cheronet Olivia , Szeverényi Vajk , Kiss Viktória , Szeniczey Tamás , Kiss Krisztián , Zoffmann Zsuzsanna K. , Koós Judit , Hellebrandt Magdolna , Maier Robert M. , Domboróczki László , Virag Cristian , Novak Mario , Reich David , Hajdu Tamás , von Cramon-Taubadel Noreen , Pinhasi Ron , Perry George H. 
Published: April 2022

SignificanceSubsistence shifts from hunting and gathering to agriculture over the last 12,000 y have impacted human culture, biology, and health. Although past human health cannot be assessed directly, adult stature variation and skeletal indicators of nonspecific stress can serve as proxies for health during growth and development. By integrating paleogenomic genotype and osteological stature data on a per-individual basis for 167 prehistoric Europeans, we observe relatively shorter than expected statures among early farmers after correcting for individual genetic contributions to stature. Poorer nutrition and/or increased disease burdens for early agriculturalists may partly underscore this result. Our integrated osteological–genetic model has exciting potential for studies of past human health and expansion into various other contexts.
Site selection for the development of organic farming for conservation purposes in the upstream of Air Bengkulu watershed, Bengkulu
Authors: Lovita V , Sulistyo B , Listyowati E A 
Published: April 2022

Abstract
Awareness of the dangers posed by the use of synthetic chemicals in farming attracts attention. The development of organic agriculture requires a suitable location. However, sometimes, suitable land is very limited. This study aims to select the site for the development of organic agriculture, as well as to function in overcoming the existence of critical land, especially in the Upstream of Air Bengkulu Watershed, Bengkulu. The research method carried out is by compiling a Map of Conservation Activity Plan (CAP) based on a model developed by the then Ministry of Environment and Forestry. Maps used for input to CAP are EHL (Erosion Hazard Level), Soil Depth, Slope, Population Pressure, and the Recommended Landuse. From the CAP Map, the sites that are estimated to be used for organic farming development locations will be obtained. Results show that the sites for CAP to support organic farming is divided, broadly, into 2 categories: (1) mixed cultivation, minimum tillage, planting of ground cover, management of organic matter and application of agroforestry covers 9.32% in Semidang Lagan and Karang Tinggi District, and (2) mixed cropping, minimum tillage, ground cover planting, organic matter management, permanent vegetation and application of agroforestry covers 38.79% in Taba Penanjung District, Bajak Dua, Jambu and Rindu Hati Village. While 51.89% of the study area in Taba Penanjung District should be used for protected area.
Modeling of Sandy Soil Compaction and Water Holding Capacity Due to Biogas Slurry Ameliorant
Authors: Yudhistira D.T. , Ngadisih  , Karyadi J.N.W. , Tirtalistyani R. , Ismail M.H. , Mawandha H.G. 
Published: April 2022

Abstract
Model could be used to study the behavior of real systems such as hydrosphere (soil system) for improving their performance as basis of decision-making that promote the sustainability. Here, the study focused on SDGs point 15, how the agriculture particularly soil management should keep the life on land. Biogas slurry (BS) is a liquid-solid mix waste from livestock that useful for soil improving soil quality. Sandy soil has some limitations when used as media of plant cultivation, mainly poor in water holding capacity and less of organic content. This study aimed to measure and explore the sandy soil quality (soil compaction, SC and water holding capacity, WHC) due to BS application. A completely randomized design (CRD) in laboratory was adopted in this study where soil and BS put in a pot of diameter and height of 8.2 cm and 12 cm, respectively. The experiment was carried out with treatment of sandy soil as control (K), sandy soil and BS dose15 ton/ha (D1), 30 ton/ha (D2), and 45 ton/ha (D3). The soil was incubated 84 days that every 14 days (incubation time, IT) the SC and WHC were measured. Mathematical model and Two Ways ANOVA Test were applied to analyze the data. Logistic equation was acceptable (R2 > 80%) to describe soil compaction behavior in sandy soil with BS ameliorant. The SC rate of K, D1, D2, and D3 treatments were - 0.0251, -0.0524, -0.0280, and -0.0360, respectively. This study revealed BS and IT significantly affect SC and WHC of sandy soil with BS ameliorant.