bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pioderma gangrenoso ampollar como forma de presentación de leucemia mieloide aguda. Informe de un caso
Authors: Bodnariuk Natali , Bastard Dolores P. , Torre Ana C. , Andresik Diego , Vallone Marcelo G. , Mazzuoccolo Luis D. 
Published: October 2022

El pioderma gangrenoso ampollar es una variedad infrecuente de pioderma gangrenoso, que se asocia en el 50-70% de los casos con trastornos oncohematológicos. Se comunica el caso de una paciente de 59 años, que consultó por fiebre y ampollas purpúricas de rápida progresión, con compromiso cutáneo mucoso. Con sospecha de una enfermedad neutrofílica, ampollar, o infección por gérmenes oportunistas, se realizó biopsia de piel para estudio histopatológico, inmunofluorescencia directa y cultivo. Los cultivos y la inmunofluorescencia directa fueron negativos, y la anatomía patológica reveló un denso infiltrado inflamatorio con predominio neutrofílico en dermis. Ante el diagnóstico de pioderma gangrenoso ampollar, se realizó una punción-aspiración de médula ósea cuyo resultado fue compatible con leucemia mieloide aguda. Se instauró tratamiento con corticosteroides sistémicos, a pesar de lo cual la paciente evolucionó desfavorablemente y falleció a los 15 días de su ingreso hospitalario.
Este caso ilustra la asociación de esta enfermedad cutánea con trastornos oncohematológicos y el mal pronóstico que esto implica a corto plazo.
ANALYSIS OF THE CATIONIC-ANIONIC COMPOSITION OF FEED
Authors: Kalyuzhnaya T. V. , Orlova D. A. 
Published: October 2022

When compiling diets for productive animals, one of the indicators taken into account is the cationanion balance, which is calculated based on the content of sodium and potassium cations and sulfate and chloride anions. The cationic-anionic composition of feed is very diverse. The lack or excess of one or another cation or anion in feed can lead to disruption of metabolic processes and various diseases of non-infectious etiology.The aim of the work was to quantify and analyze the cationanion composition of feed for productive animals by capillary electrophoresis.The research was carried out in the conditions of the educational and research center for the examination of food and animal feed of the St. Petersburg State University of Veterinary Medicine. 76 samples of various feeds for productive animals were used as research materials: 19 samples of grass flour, cake, mixed feeds for cattle.The study of the cationic composition of the studied feed samples was carried out, guided by the methodology M 04-65-2010 «Feed, compound feed and raw materials for their production. The method of measuring the mass fraction of ammonium, potassium, sodium, magnesium and calcium cations by capillary electrophoresis using the capillary electrophoresis system «Kapel», and anionic composition – according to the method M 04 -73-2011 «Feed, compound feed and raw materials for their production. The method of measuring the mass fraction of water-soluble forms of chloride, sulfate, nitrate and phosphate ions by capillary electrophoresis using the capillary electrophoresis system «Kapel» (GC «LUMEX»).Thus, analyzing the results obtained, it was found that in all samples of feed for productive animals, the mass fraction of cations and anions varied depending on the type of cation or anion and feed.Determination of the cationic-anionic composition of feed is a necessary condition for the formation of a full-fledged diet that provides the body of productive animals with nutrients, which is especially important in modern conditions of intensification of animal husbandry and agricultural development.
OVARIOREMINANT SYNDROME IN BITCHES AFTER OVARIOGYSTEROECTOMY
Authors: Poluektov E. A. , Payterova V. V. , Abdulloyev H. S. 
Published: October 2022

Female ovariohysterectomy is one of the most common surgical interventions aimed at preventing diseases of the reproductive system and regulating the number, incl. in neglected animals. This is an abdominal operation that can be performed by various techniques. Complications after ovariohysterectomy occur infrequently, incl. reminant ovary syndrome is extremely rare.According to the results of numerous studies, bitches and cats are preferably spayed before the first estrus. Thus, reducing the risk of neoplasms of the breast, ovaries and uterus.The aim of our study was to determine the incidence of ovarioreminant syndrome in bitches after ovariohysterectomy/ovariectomy and to work out the technique for searching for residual/ectopic ovarian tissues.The study was conducted from 01.12.2020 to June 2022 in the conditions of the network of veterinary clinics "Alisavet" in Moscow. The object of the study were 557 clinically healthy females over the age of 8 months of various breeds. Castration was performed by standard laparotomy and endoscopically. Each dog underwent preoperative blood tests (general and biochemical tests), ultrasound of the genitourinary system, ECHO-KG, and an electrocardiogram was also performed for large animals.A day after surgery, ultrasound was performed using the Mindray Vetus 7 machine to check for early postoperative complications, ECHO-CG was also performed using the Mindray Vetus 7. An electrocardiogram was recorded using the Neurosoft Polyspectre 8/B. Calculation of parameters of the general blood test was carried out on the analyzer Mindray BC-2800 Vet, biochemical blood parameters - on the biochemical analyzer Fujifilm Dri-chem NX500i or in the laboratories of Mos-cow (Mitrokhina laboratory, Vetunion). All the results obtained during the research were processed statistically using Microsoft Excel.
Reconstruction Of Lower Limb Wide Defects With Perforator Flaps: Alternative Solution To Reconstruction With Free Flap
Authors: RİZVANOVİC Zumreta , CİNPOLAT Anı , SEYHAN Tamer 
Published: October 2022

Objective: Repair of lower limb congenital or acquired tissue defesct in proper shape and function is the main topic of plastic surgery. In this article, we investigated different treatment methods of this anatomical region which is difficult to reconstruction and alternative solution methods to reconstruction with free flap, and also reviewed the treatment algorithm depending on the localization and size of the defect.
Material and Methods: In this study; between 2011 and 2017, 27 patients who were surgically treated with a soft tissue defect in the lower extremity were evaluated according to treatment alternative for defect location and advantages of perforator flap to free flap. There were lower extremity soft tissue defect located in the proximal 1/3 cruris in 7 patients, in the middle 1/3 cruris in 12 patients and in the distal 1/3 cruris in 8 patients.
Result: Early venous congestion was observed in 3 cases and wound infection was observed in 1 case. Venous congestion resolved spontaneously, wound infection healed with appropriate wound care. In 3 cases, partial flap loss was observed distal to the flap, and was treated with wound care without the need for a second operation.
Conclusion: Perforator flaps are a reliable and effective method for repairing soft tissue defects of the lower limbs and it can be applied successfully in the early period after trauma. We think that it can be applied safely cause of the surgical technique is relatively easy and does not require microsurgery.
Evaluation of the knowledge, attitudes and behaviors of people who have not yet been vaccinated during the Covid-19 vaccination process
Authors: DEMİRKÖSE Hacer , GÖKLER Mehmet Enes 
Published: October 2022

Purpose: In the study, it was aimed to understand the factors affecting the acceptance of the Covid-19 vaccine in Pursaklar district of Ankara, to identify common barriers to vaccination decisions, and to determine the necessary interventions to improve vaccination rates.
Materials and Methods: The type of research is cross-sectional. A total of 370 people participated in the study. As a data source in the research, the questionnaire form "Evaluation of Information, Attitudes and Behaviors of People Who Have Not Been Vaccinated in the Covid-19 Vaccination Process in Ankara Pursaklar District" was used.
Results: Among the reasons for not being vaccinated yet, although it was time for vaccination, the most common answers were 'there was no time/opportunity to get vaccinated' with 41.5% and 'I don't want to be vaccinated' with 40%. The attitudes of the participants about the Covid-19 vaccine after this survey are as follows; 27.3% “I will definitely get vaccinated”, 25.9% “I will probably get vaccinated”, 13.5% “I will definitely not get vaccinated”, 15.4% “I will probably not get vaccinated” and 17.8% “I have no idea”. In the model established by the multivariate logistic regression analysis, in which the factors affecting the unvaccinated status were examined, being in the 30-44 age range (OR: 2,646), not having Covid-19 before (OR: 3,832), not wanting to receive information from a physician about Covid-19 vaccines (OR:3,461) were definitely determined as effective factors on not getting vaccinated
Conclusion: The high level of Covid-19 vaccine hesitancy, especially fueled by conspiracy theories on television and social media, can severely limit the effectiveness of currently ongoing vaccine programs. It is extremely important that these platforms transfer information in a controlled manner.
Brusatol'ün Renal İskemi Reperfüzyon Hasarına Karşı Renoprotektif Etkileri
Authors: EKİNCİ AKDEMİR Fazile Nur , TANYELİ Ayhan , ERASLAN Ersen , GÜLER Mustafa Can , TOPDAĞI Ömer , NACAR Tuncer 
Published: October 2022

Purpose: The aim of this study was to determine the potential beneficial effects of brusatol treatment on oxidative kidney injury induced by bilateral renal ischemia reperfusion (RIR) method.
Material and Method: In the existing study, experimental animals were randomly assigned to 4 groups as sham, renal ischemia reperfusion (RIR), DMSO and brusatol groups. Sham group; the back region was opened by incision and then sutured but no ischemia reperfusion (IR) model was established. In RIR group, 1 hour of ischemia following 24 hours of reperfusion was formed. In DMSO group, 0,3 ml, 1% DMSO was administered intraperitoneally for each rat once in two 2 days for 10 days and a last dose was applied 30 minutes before reperfusion. Then IR model was carried out as told in RIR group. In brusatol group, brusatol was applied intraperitoneally as 0,5 mg/ml for each rat every second days for 10 days before the experiment. The last dose was administered 30 minutes before reperfusion and IR was fulfilled as depicted in RIR group. Following reperfusion period, rats were immolated and renal tissues were isolated.
Results: TNF-α, MDA and IL-1β levels, OSI, TOS and MPO values were significantly raised but TAS and SOD levels were declined in RIR and DMSO groups compared to sham group. On the other side, TAS and SOD increased while OSI and TOS values, activity of MPO and TNF-α, MDA and IL-1β levels were significantly reduced in brusatol+I/R group due to brusatol therapy compared to sham and DMSO groups.
Conclusion: Consequently, brusatol demonstrated protective effects against RIR induced oxidative kidney injury in rats.
Síntesis quimioenzimática de ésteres metílicos de ácidos grasos a partir de aceite residual y cálculo de sus parámetros fisicoquímicos
Authors: Sustaita-Rodríguez Alejandro , Ruiz-Gutiérrez Martha Graciela , Ramos-Sánchez Víctor Hugo , Beltrán Piña Blanca Gladiana , Hernández-Ochoa León , Chávez Flores David 
Published: October 2022

Mediante el desarrollo de un diseño factorial 2k se evaluó la temperatura y concentración del catalizador en la reacción para la obtención de ésteres metílicos de ácidos grasos (FAME) utilizando aceite residual como sustrato metanol como aceptor de acilo Candida antarctica Lipasa B como catalizador y tamices moleculares como agente secante. Los datos experimentales se analizaron con un análisis de varianza (ANOVA). Las relaciones óptimas de catalizador-temperatura se determinaron a 13% -30 ° C, 14,5% -34 ° C y 14% -35 ° C. No se detectó ningún efecto de los tamices moleculares en el rendimiento de la reacción. Por el contrario, se registró para la acidez del producto, que mostró una disminución significativa, de 0,79 a 0,40 mg KOH / g. Aplicando las reglas de mezcla, se calcularon las propiedades fisicoquímicas de los FAME (densidad, gravedad API, viscosidad cinemática, punto de enturbiamiento, presión de vapor, índice de cetano y capacidad calorífica). Los resultados establecieron que el biocombustible es apto para uso comercial y cumple con las regulaciones para biocombustibles: ASTM D6751 y EN-14214. Se determinó que el terc-butanol es el disolvente óptimo para la recuperación y reutilización de la lipasa.

DOI: https://doi.org/10.54167/tecnociencia.v15i1.755
Methanol detection in commercial sanitizing gels, during the COVID-19 Pandemic
Authors: De la Torre Sáenz Luis , Lardizábal-Gutiérrez Daniel , Estrada-Guel Ivanovich , Paraguay-Delgado Francisco 
Published: October 2022

The ethanol (active) and methanol (toxic) substances content were quantified for commercial sanitizing gels. The health emergency caused by the COVID-19 epidemic has motivated to production of sanitizing gels to cover higher demand. The analytical composition of 24 commercial gels is reported (15 produced by national and transnational companies, and 9 collected gels which were in use at public areas). From the results it was found, that only one brand of 15 gels meets the quality requirements regarding 70% (wt./wt.) of ethanol content. Concerning to the collected gels, none of them contains the minimum active compound required. The non-compliance of this requirement means that these gels present its sanitizing action diminished. A striking result is that 25% of commercially packaged gels contain methanol - a toxic substance - in alarming amounts, hundreds of times more than the FDA upper limits requirement.

DOI: https://doi.org/10.54167/tecnociencia.v15i1.761
Preface: 5th International Workshop on Education Reform and Social Sciences (ERSS 2022)
Authors: Harris Darlene , Huang Shuhan 
Published: October 2022

This proceeding includes original and peer-reviewed research papers from the 5th International Workshop on Education Reform and Social Sciences (ERSS 2022), held from October 15-16, 2022 in Hong Kong, China.
The aim of ERSS 2022 is to provide a platform for educators, scholars, managers and graduate students from different cultural backgrounds to present and discuss research, developments and innovations in the fields of Education Reform & Social Science. It provides opportunities for the delegates to exchange new ideas and application experiences, to establish business or research relations and to find global partners for future collaboration.
ERSS 2022 received 168 manuscripts. And more than 50 submissions had been accepted by our reviewers. By submitting a paper to ERSS 2022, the authors agreed to the review process and understood that papers undergo a peer-review process. Manuscripts were reviewed by appropriately qualified experts in the field selected by the Conference Committee, who gave detailed comments and-if the submission was accepted the authors would submit a revised version that considered this feedback. All papers were reviewed using a double-blind review process: authors declared their names and affiliations in the manuscript for the reviewers to see, but reviewers did not know each other’s identities, nor did the authors receive information about who had reviewed their manuscript. The Committees of ERSS 2022 invested great efforts in reviewing the papers submitted to the conference and organizing the sessions to enable the participants to gain maximum benefit.
With our warmest regards,
Conference Organizing Committees
Schaarste en medewerkingsplicht
Authors: de Haan F.H. 
Published: October 2022

Schaarste en medewerkingsplicht
Hulpverleners, zoals medisch-specialistische instellingen, hebben onder de Wgbo de plicht zorg te verlenen als een goed hulpverlener. Daar hoort ook de zorg voor de continuïteit van zorg bij. Daar moeten patiënten aan meewerken. Zij kunnen dus niet onbegrensd eisen stellen aan de plaats waar zij nadere zorg krijgen.
PEMANFAATAN DIGITAL MARKETING PADA UMKM LOKAL UNTUK PEMULIHAN EKONOMI DI KELURAHAN KAUMAN KECAMATAN SRENGAT KABUPATEN BLITAR
Authors: Mukhlison  , Hendri Budi Santoso  , Anisa Septiana Astikawati  , Intan Permata Sari  , Ina Virdiana Wulandari  
Published: October 2022

Digital Marketing adalah konsep strategi pemasaran barang/jasa yang menggunakan sistem digital yang memiliki tujuan untuk memperluas pangsa pasar dan menjaring konsumen baru yang berpotensial guna untuk meningkatkan omset penjualan para pelaku UMKM. Adapun tujuan dari penelitian ini adalah untuk memberikan sosialisasi kepada para pelaku UMKM lokal agar bisa memanfaatkan Digital Marketing guna untuk meningkatkan pemasaran produk UMKM lokal, khususnya pada industri olahan makanan dan minuman dan mengoptimalkan penggunaan digital marketing oleh pelaku UMKM dengan harapan untuk meningkatkan pemulihan ekonomi di Kelurahan Kauman Kecamatan Srengat Kabupaten Blitar. Hasil dari penelitian ini menyatakan bahwa konsep digital marketing perlu diterapkan oleh pelaku usaha agar mampu meningkatkan penjualan dan menjangkau pasar yang lebih luas. Strategi yang dilakukan untuk membantu pelaku UMKM dalam memanfaatkan digital marketing, yakni dengan memberikan sosialisasi dan pelatihan dalam penerapan konsep digital marketing dan bekerja sama dengan pemerintah desa untuk mengadakan kegiatan penyuluhan atau pemberdayaan pelaku UMKM dengan berbasis pemasaran digital.
ANALISIS SELF AFFECACY SEBAGAI INTERVENING, PENGETAHUAN BERWIRAUSAHA DAN TEKNOLOGI INFORMASI TERHADAP MINAT BERWIRAUSAHA MAHASISWA FEB UNTAG SEMARANG
Authors: Muchayatin Muchayatin  
Published: October 2022

This research aims to determine the influence of knowledge of entrepreneurship, information technology and self-affecacy on the interest in entrepreneurship in students of the Faculty of Economics and Business, University of August 17, 1945 Semarang. The population in this study was 339 students of the Faculty of Economics and Business, University of 17 August 1945 Semarang. The sample size is 80 students with sampling techniques using proportionate ramdom sampling. Analaisis technique uses multiple regression findings from this study firstly entrepreneurial knowledge, information technology and self-affecacy have a positive and significant effect on the interest in entrepreneurship and secondly entrepreneurial knowledge, information technology has a positive and significant effect on self-affecacy.
Nanoparameters in Western Iberian Romance
Authors: Gravely Brian , Gupton Timothy 
Published: October 2022

In this paper, we address two separate cases of null-copular constructions in Galician and Asturian that on the surface appear to be identical but exhibit subtle yet important differences. We show that these differences entail theoretical assumptions that distinguish their underlying syntactic operations. Furthermore, we propose that the unification of both instances of null-copular constructions lies in nanoparametric variation (Biberauer & Roberts 2015b), which differs from microparameteric variation in the sense that the former is only acquired by the learner in a “bottom up” fashion via direct evidence. That is, nanoparametric phenomena do not constitute a parameter setting that may be indirectly acquired based on indirect evidence.
Demirjian’s dental age estimation accuracy among Ukrainian. Transcarpathian children sample: pilot study
Authors: Goncharuk-Khomyn Myroslav , Hirschowitz Wayne , Kvaal Sigrid , Cavalcanti Alessandro , Yavuz Yasemin 
Published: October 2022

Background. Number of forensic methods have been proposed for dental age estimation, while parameter of dental age itself is demonstrating a high level of correspondence with chronological age. Analysis of available literature revealed deŢciency of studies regarding applicability of using Demirjian’s age estimation technique among Ukrainian samples for forensic purpose.
Objective. To evaluate accuracy of original Demirjian’s dental age estimation method amongsamp le of Ukrainian Transcarpathian children.
Materials and Methods. Study was organized as retrospective by the design based on the analysis of 276 digital panoramic X-ray images obtained from the patients of University Dental Clinic aged 6.0-15.99 years old. Dental age estimation was held by the originally proposed Demirjian’s technique.
Results. Dental age estimation using Demirjian’s technique provoked overestimation effect on 0.43 years among patients aged 6.0-6.99 years, on 0.49 years among patients aged 7.0-7.99 years, on 0.47 years among patients aged 8.0-8.99 years, on 0.55 years among patients aged 9.0-9.99 years, on 0.51 years among patients aged 10.0-10.99 years, on 0.55 years among patients aged 11.0-11.99 years, on 0.44 years among patients aged 12.0-12.99 years, on 0.45 years among patients aged 13.0-13.99 years, on 0.54 years among patients aged 14.0-14.99 years, on 0.58 years among patients aged 15.0-15.99 years.
Conclusion. Demirjian’s dental age estimation technique may be used for forensic purposes among population of children from Ukrainian Transcarpathia, if accuracy of other available dental age estimation methods would not be validated till the moment of needed forensic investigation.
Kegiatan Bongkar Pasang melalui Aplikasi Phet Virtual Laboratory pada Listrik Dinamis
Authors: Triza Harnofa 
Published: October 2022

Penelitian ini bertujuan untuk memecahkan masalah minimnya aktivitas belajar fisika, mengetahui pelaksanaan pembelajaran bongkar pasang pada aplikasi phet virtual lab dapat meningkatkan hasil belajar fisika serta mendeskripsikan hambatan dalam pelaksanaan pembelajaran bongkar pasang pada aplikasi phet virtual laboratory. Sebagai Subjek dari penelitian ini siswa kelas XII IPA1 MAN 1 Solok. Pembelajaran Fisika Asyik kegiatan bongkar pasang melalui aplikasi Phet virtual laboratory pada listrik dinamis ini menggunakan metode Inquiry Learning, dimana peserta didik dituntun untuk menemukan , menanamkan dasar-dasar berfikir ilmiah sehingga dalam proses pembelajaran mereka lebih banyak untuk belajar sendiri, dapat mengembangkan kreativitas dalam memecahkan masalah. Permasalahan belajar Fisika khususnya pada kelas XII IPA MAN 1 Solok yang selama ini terlalu monoton dengan metode ceramah, diskusi dan penugasan, sehingga output dari pembelajaran masih rendah. ini disebabkaan tak lain karena kesulitan peserta didik dalam memahami konsep tentang Listrik Dinamis. Dengan menerapkan konsep pembelajaran menggunakan aplikasi phet ternyata dapat meningkatkan aktivitas dan hasil belajar peserta didik. Hal ini terlihat dengan begitu semangatnya peserta didik dalam kegiatan pembelajaran yang diberikan,membuat suatu rangkaian, membongkar dan memasang lagi rangkaian baru dengan komponen yang baru, dan menemukan hal yang baru dalam berkreativitas. Pemecahan masalah belajar fisika dilihat dari pencapaian hasil belajar juga terdapat peningkatan dalam hasil belajar. Pencapaian hasil belajar peserta didik kelas XII IPA1 secara umum telah melampaui pencapaian KKM. Maka kegiatan pembelajaran Bongkar Pasang melalui aplikasi phet secara Virtual Laboratory yang diterapkan dapat dikatakan berhasil. Artinya gagasan tersebut merupakan inovasi pembelajaran yang berhasil dengan baik.