bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low-Cost “Telesimulation” Training Improves Real Patient Pediatric Shock Outcomes in India
Authors: James Ebor Jacob G. , Vyasam Siva , Venkatachalam Shakthi , Sanseau Elizabeth , Cassidy Kyle , Ramachandra Geethanjali , Rebekah Grace , Adhikari Debasis D. , Deutsch Ellen , Nishisaki Akira , Nadkarni Vinay M. 
Published: July 2022

IntroductionPediatric shock, especially septic shock, is a significant healthcare burden in low-income countries. Early recognition and management of shock in children improves patient outcome. Simulation-based education (SBE) for shock recognition and prompt management prepares interdisciplinary pediatric emergency teams in crisis management. COVID-19 pandemic restrictions on in-person simulation led us to the development of telesimulation for shock. We hypothesized that telesimulation training would improve pediatric shock recognition, process of care, and patient outcomes in both simulated and real patient settings.Materials and MethodsWe conducted a prospective quasi-experimental interrupted time series cohort study over 9 months. We conducted 40 telesimulation sessions for 76 participants in teams of 3 or 4, utilizing the video telecommunication platform (Zoom©). Trained observers recorded time-critical interventions on real patients for the pediatric emergency teams composed of residents, fellows, and nurses. Data were collected on 332 pediatric patients in shock (72% of whom were in septic shock) before, during, and after the intervention. The data included the first hour time-critical intervention checklist, patient hemodynamic status at the end of the first hour, time for the resolution of shock, and team leadership skills in the emergency room.ResultsThere was a significant improvement in the percent completion of tasks by the pediatric emergency team in simulated scenarios (69% in scenario 1 vs. 93% in scenario 2; p &lt; 0.001). In real patients, completion of tasks as per time-critical steps reached 100% during and after intervention compared to the pre-intervention phase (87.5%), p &lt; 0.05. There was a significant improvement in the first hour hemodynamic parameters of shock patients: pre (71%), during (79%), and post (87%) intervention (p &lt; 0.007 pre vs. post). Shock reversal time reduced from 24 h pre-intervention to 6 h intervention and to 4.5 h post intervention (p &lt; 0.002). There was also a significant improvement in leadership performance assessed by modified Concise Assessment of Leader Management (CALM) instrument during the simulated (p &lt; 0.001) and real patient care in post intervention (p &lt; 0.05).ConclusionTelesimulation training is feasible and improved the process of care, time-critical interventions, leadership in both simulated and real patients and resolution of shock in real patients. To the best of our knowledge, this is one of the first studies where telesimulation has shown improvement in real patient outcomes.
Ride-hailing services: Competition or complement to public transport to reduce accident rates. The case of Madrid
Authors: Flor María , Ortuño Armando , Guirao Begoña 
Published: July 2022

IntroductionThe transport and mobility sector is experiencing profound transformations. These changes are mainly due to: environmental awareness, the increase in the population of large urban areas and the size of cities, the aging of the population and the emergence of relevant technological innovations that have changed consumption habits, such as electronic commerce or the sharing economy. The introduction of new services such as Uber or Cabify is transforming urban and metropolitan mobility, which has to adapt to this new scenario and the very concept of mobility.ObjectiveThus, the purpose of this study was to evaluate whether ride-hailing platforms substitute or complement public transport to reduce accident rates, considering the two basic transport zones of Madrid: “The Central Almond” and the periphery.MethodsThe data were collected from the 21 districts of Madrid for the period 2013–2019, and they were analyzed by a Random Effects Negative Binominal model.ResultsThe results obtained in this study suggest that since the arrival of Uber and Cabify to the municipality of Madrid the number of fatalities and serious injuries in traffic accidents has been reduced. Traffic accidents on weekends and holidays, with at least one serious injury or death, have also been reduced. However, the number of minor injuries has increased in the central districts of Madrid.ConclusionOverall, what was found in this study supports the hypothesis that these services replace the urban buses. However, these services improve the supply to users with greater difficulties to access taxis or public transport, constituting an alternative mode of transport for high-risk drivers. Therefore, such findings may be quite useful for policy makers to better define regulatory policies for these services.
Predictive value of the systemic immune-inflammation index for cancer-specific survival of osteosarcoma in children
Authors: Ouyang Haiping , Wang Zhongliang 
Published: July 2022

BackgroundOsteosarcoma (OS) is the primary malignant bone tumor that most commonly affects children and adolescents. Recent years effective chemotherapy have improved the 5-year survival in osteosarcoma patients to up to 60%-70%. Still, there is a lack of novel therapeutic strategies to enhance further survival. Our study aimed to evaluate the clinical significance of pretreatment inflammatory-based parameters, including PLT, NLR, and SII, as prognostic indicators of survival in pediatric osteosarcoma patients.MethodsA total of 86 pediatric osteosarcoma patients between 2012 and 2021 in the Department of Orthopedics or tumor Surgery of Children's Hospital affiliated to Chongqing Medical University were retrospectively analyzed. The clinicopathological variables and systematic inflammatory biomarkers, including NLR, PLR and SII, was performed by the A Receiver operating characteristic (ROC) curve and Cox proportional risk regression model. According to the results of multivariate analysis, a prognostic nomogram was generated, and the concordance index (C-index) was calculated to predict the performance of the established nomogram. The survival curve was plotted by the Kaplan-Meier method.ResultsUnivariate analysis showed that TNM stage, tumor size, NLR value, PLR value, SII value, neutrophil count and platelet count were related to CSS (p &lt; 0.05). According to multivariate analysis, only TNM stage (p = 0.006) and SII values (p = 0.015) were associated with poor prognosis.To further predict survival in pediatric osteosarcoma patients, multivariate Cox regression analysis was used to predict cancer-specific survival at 1, 3 and 5 years. And constructed a nomogram model to predict children's CSS. The C-index of the nomogram is 0.776 (95%CI, 0.776–0.910), indicating that the model has good accuracy.ConclusionPreoperative SII and TNM staging are independent prognostic markers for pediatric osteosarcoma patients. SII may be used in conjunction with TNM staging for individualized treatment of pediatric osteosarcoma patients in future clinical work.
Highly Virulent and Multidrug-Resistant Escherichia coli Sequence Type 58 from a Sausage in Germany
Authors: Eger Elias , Domke Marielle , Heiden Stefan E. , Paditz Madeleine , Balau Veronika , Huxdorff Christiane , Zimmermann Dirk , Homeier-Bachmann Timo , Schaufler Katharina 
Published: July 2022

Studies have previously described the occurrence of multidrug-resistant (MDR) Escherichia coli in human and veterinary medical settings, livestock, and, to a lesser extent, in the environment and food. While they mostly analyzed foodborne E. coli regarding phenotypic and sometimes genotypic antibiotic resistance and basic phylogenetic classification, we have limited understanding of the in vitro and in vivo virulence characteristics and global phylogenetic contexts of these bacteria. Here, we investigated in-depth an E. coli strain (PBIO3502) isolated from a pork sausage in Germany in 2021. Whole-genome sequence analysis revealed sequence type (ST)58, which has an internationally emerging high-risk clonal lineage. In addition to its MDR phenotype that mostly matched the genotype, PBIO3502 demonstrated pronounced virulence features, including in vitro biofilm formation, siderophore secretion, serum resilience, and in vivo mortality in Galleria mellonella larvae. Along with the genomic analysis indicating close phylogenetic relatedness of our strain with publicly available, clinically relevant representatives of the same ST, these results suggest the zoonotic and pathogenic character of PBIO3502 with the potential to cause infection in humans and animals. Additionally, our study highlights the necessity of the One Health approach while integrating human, animal, and environmental health, as well as the role of meat products and food chains in the putative transmission of MDR pathogens.
Reduced Rainfall Variability Reduces Growth of Nothofagus alessandrii Espinosa (Nothofagaceae) in the Maule Region, Chile
Authors: Santelices-Moya Rómulo , Gibson-Carpintero Stephanie , Cabrera-Ariza Antonio , Santini-Junior Luiz , Venegas-González Alejandro 
Published: July 2022

Nothofagus alessandrii Espinosa is an endemic species of the coastal Maulino forest of central Chile that has historically been severely threatened by the reduction of its habitat and the isolation of its fragments. In addition, a gradual reduction in precipitation has been observed in recent years across its entire natural distribution area. Although the genus Nothofagus has been extensively analyzed in dendrochronological studies in the Southern Hemisphere, the dendrochronological potential of this species is unknown. In this study, we developed a novel tree-ring chronology of N. alessandrii in order to examine the climate sensitivity of the radial growth and to thus understand its response to climate change in central Chile. Our ring-width chronology showed a series intercorrelation value of 0.48 for the period of 1942–2016 (EPS < 0.85, with 10 trees), showing a strong common growth signal among the trees. N. alessandrii growth was strongly influenced by precipitation from May to November (the austral winter and spring seasons), while the temperature signal was weak. We observed that the radial growth patterns of N. alessandrii chronology showed upward growth trends, with a marked positive slope until the mid-1980s. However, a negative trend was observed for the period of 1985–2016, which was related to the increased drought conditions (rainfall and soil moisture reductions) in past decades and affected the entire natural distribution of the species. We suggest that drier winters and springs would slow the growth of this species. This information is of vital importance to understanding the growth dynamics of N. alessandrii, a critically endangered species, and to take on urgent adaptation and mitigation measures in the face of climate change.
ANTOCIANINAS COMO BIOSENSORES EN LA CONSERVACIÓN DE ALIMENTOS
Authors: Molina Arteaga Nadya Isabel , Toala-Zambrano Alisson Nicolle , Sanchéz Francisco , Macías-Pro Michael Aníbal , Rosero-Delgado Ernesto Alonso 
Published: July 2022

Este estudio presenta un primer acercamiento hacia la aplicabilidad de antocianinas como biosensores en la conservación de alimentos. La materia prima utilizada fue la col morada (Brassica oleracea var. capitata f. rubra); mediante una extracción sólido-líquido se lograron obtener soluciones con una concentración de antocianinas entre 45,69 y 46,71 mg Cianidina-3-glucósido/g col morada. Se evaluó el comportamiento de las antocianinas a diferentes cambios de pH (4, 6, 8,10), presencia de etanol (5%,9%,13% y 16%), hidróxido de amonio (5%,10%,15% y 20%), y exposición a la luz (1, 24, 48 72h), así como a cambios de temperatura (4 y 30 °C); factores que pueden presentarse durante el deterioro de los alimentos. Los resultados mostraron que las antocianinas presentan sensibilidad a variaciones de pH entre 4 y 10 con absorbancias entre 0,471 y 0,126 (cambios de color entre morado y verde), a la presencia de hidróxido de amonio en concentraciones entre el 5 % y 20% con absorbancias entre 0,424 y 0,175 (cambios de color entre rosa y amarillo). El estudio demuestra la viabilidad de las antocianinas de la col morada para ser utilizadas en el desarrollo de etiquetas inteligentes las cuales permitan la detección in-situ del deterioro de un alimento envasado.

Palabras clave: Etiqueta inteligente, antocianinas, deterioro, envasados.

Abstract
This study presents a first approach towards the applicability of anthocyanins as biosensors in food preservation. The raw material used was purple cabbage (Brassica oleracea var. capitata f. rubra); through solid-liquid extraction, solutions with anthocyanin concentration between 45.69 and 46.71 mg Cyanidin-3-glucoside/g purple cabbage were obtained. The behavior of anthocyanins was evaluated at different pH changes (4, 6, 8.10), presence of ethanol (5%, 9%, 13% and 16%), ammonium hydroxide (5%, 10%, 15 % and 20%), and exposure to light (1, 24, 48, 72h), as well as changes in temperature (4 and 30 °C); factors that may appear during food spoilage. The results showed that anthocyanins are sensitive to pH variations between 4 and 10 with absorbances between 0.471 and 0.126 (color changes between purple and green), to the presence of ammonium hydroxide in concentrations between 5% and 20% with absorbances between 0.424 and 0.175 (color changes between pink and yellow). The study demonstrates the feasibility of purple cabbage anthocyanins to be used in the development of smart labels which allow in-situ detection of the deterioration of a packaged food.
Pengaruh Prinsip Non-Intervensi ASEAN terhadap Upaya Negosiasi Indonesia Dalam Menangani Konflik Kudeta Myanmar
Authors: Ramadhani Zahratunnisa , Mabrurah Mabrurah 
Published: July 2022

On 1 February 2021 Myanmar's democratization was once again threatened, following a military junta coup against the Government of Myanmar, by detaining several leaders, including Myanmar President Win Myint and Aung san suu kyi, the State Advisor. This study aims to analyze the Indonesia government's efforts to disarm the current conflict in Myanmar, while still respecting the principle of non-intervention, a mutual agreement between the ASEAN members. The method of research chosen is qualitative descriptive using techniques used for data collection through journals, papers, web sites and other reliable sources. Moreover, to strengthen the argument, the author uses the constructivism theory of Alexander Went which is linked by an analysis of Indonesia's efforts in the conflict in Myanmar. This study focuses on the effect of the ASEAN non-intervention principle on Indonesia's conflict resolution efforts. The results of this study show that the application of the ASEAN principle of non-intervention by ASEAN on the one hand gives Member States the flexibility to solve their internal problems without any interference from other countries. however, on the other hand, this principle becomes a barrier for ASEAN member countries to implement certain mechanisms in some cases, such as the current case of the coup conflict.

Keywords : The principle of non-intervention, Myanmar Conflict, Negotiation
Peran Media Sosial Sebagai Alat Propaganda Dalam Konflik Nagorno Karabakh Antara Armenia Dan Azerbaijan
Authors: Qarayeva Leyla , Yani Yanyan Mochamad , Setiabudi Widya 
Published: July 2022

The purpose of this paper is to explain how social media has become a new space for political discussion. The use of social media to report on conflicts, influence political perceptions, voice opinions about conflicts, and solicit public support around the world. As is the case with the Nagorno Karabakh ethnical conflict between Armenia and Azerbaijan which cannot be separated from social media. In this conflict, social media was also used to ask for public support around the world to side with one of the countries in the Nagorno Karabakh Conflict. This paper will also examine how governmental and non-governmental actors use social media as a tool of propaganda and how the international community is a part of spreading propaganda in the Nagorno Karabakh conflict. To help the author in the analysis process, at least the author uses several conceptual frameworks, including the role of social media in international relations, propaganda and identity conflicts in international relations.
Keywords : Armenia; Azerbaijan; Ethnic Conflict; Nagorno Karabakh; Propaganda; Social Media
A Folklore Litigation in the Novel Agnaadi by Poomani
Authors: M Balamurugan , M Balasubramaniyan 
Published: July 2022

Nadar is a term used to describe the primitive manner of life of the human race. People's daily routines and customs are considered to be customs. An ethnic civilization is thought to have developed when customs alter over time and transform into cultural symbols. Every race still retains elements of its traditional dialects even after civilization has advanced. Poomani is regarded as one of the regional authors. He allows the writing to take on its own qualities by combining the aroma of the soil with the free-flowing energies of life. Through the short story ‘Aruppu’, he was introduced to the world of Tamil short stories. Poomani has the ability to write about rural life and aspects of ethnic culture. He wrote a book titled "Agnaadi" in 2012 after researching the history of the residents of Kalingal hamlet in Kovilpatti district. The book won the Sahitya Akademi Award in the year 2014 for its inventive ethnographic history and narrative. The word Agngnaadi means' mother'. It is a term used by certain ethnic groups. In that way, Poomani’s Agnaadi which has recorded rural life has also recorded folk liturgies. This article examines the novel Agnaadi as a case of folklore litigation.
Pelatihan Pengenalan dan Penanganan Kegawatdaruratan Henti Jantung di Luar Rumah Sakit pada Karang Taruna
Authors: Erna Dwi Wahyuni , Sriyono Sriyono , Dewi Yulis Setia , Ninuk Dian Kurniawati , Qonaah Arina , Hakim Zulkarnain 
Published: July 2022

Kejadian henti jantung dapat terjadi kepada siapa saja, di mana saja dan kapan saja. Henti jantung di luar rumah sakit merupakan salah satu kasus kegawatdaruratan dan diperlukan pengenalan dan penanganan yang cepat dan tepat sejak kejadian, baik oleh tenaga kesehatan maupun orang awam untuk meningkatkan tingkat survival korbannya. Kesiapan masyarakat, salah satunya karang taruna diperlukan. Namun, anggota Karang Taruna Trisula di Desa Sukorejo belum pernah mendapatkan pelatihan tentang pengenalan dan penanganan korban henti jantung, sehingga masyarakat belum memiliki pengetahuan dan keterampilan yang cukup dalam melakukan penanganan henti jantung di luar rumah sakit.

Tujuan dari pengabdian masyarakat ini adalah memberikan pengetahuan dan kemampuan kepada anggota Karang Taruna Trisula dalam melakukan pengenalan dan penanganan henti jantung dengan pelatihan Basic Life Support (BLS). Metode yang digunakan dalam pemberdayaan ini adalah ceramah dan simulasi tentang pengenalan dan penanganan henti jantung, serta menggunakan media video dan modul. Sebanyak 31 orang yang terdiri dari pengurus dan anggota karang taruna mengikuti kegiatan ini dan juga dilakukan evaluasi tentang pengetahuan melalui pre-test dan post-test. Hasil yang dicapai melalui kegiatan ini adalah terdapat peningkatan pengetahuan (rerata meningkat 35,8 poin) dan kemampuan dalam melakukan pengenalan dan penanganan henti jantung di luar rumah sakit. Hal ini dikarenakan metode ceramah, simulasi, dan juga media video dapat memberikan gambaran yang jelas secara teknis sehingga peserta mengetahui dan dapat mempraktikkan BLS dengan baik. Kegiatan pengabdian masyarakat berikutnya diharapkan dapat mencapai sasaran yang lebih luas dan komunitas yang beragam.
Development of Arabic Text Translation Teaching Materials For Students At Al-Fauzan Islamic Boarding School Lumajang
Authors: Syaifuji Achmad , Istiqomah Ita Nur , Ulumuddin Ihya' 
Published: July 2022

The background of the research at the Al Fauzan Islamic Boarding School Lumajang is related to the ability of students who are still relatively lacking in translating Arabic texts. This problem occurs due to many reasons including a lack of enthusiasm in the learning. Likewise, the learning method is limited to listening to the teacher's explanation then students come forward to read and translate the book. The method used by the researcher is the Research and Development (R&D). The results of data analysis are as follows: 1) product specifications include book form, book content, translation, and evaluation 2) Validation of the development of translation teaching materials, namely validation of content validators and design validators 3) The effectiveness of developing speaking skills learning media is known through the SPSS application, where the data entry of the ' pre-test and post-test students to determine production efficiency, the researcher chose a test with the type of Sample Paired Test which has a basic formula, if the value of sig. 2-tailed less than 0.05 means indicating a significant difference between pre-test and post-test. Meanwhile, the data obtained by the researcher was 0.00, indicating that the value of sig. 2-tailed less than 0.05. So that student learning outcomes showed significant positive changes after using the developed product, namely in the form of translation teaching materials for Arabic texts at the Al Fauzan Islamic Boarding School Lumajang.
خلفية البحث في معهد الفوزان الإسلامي لوماجانج لايزال كفاءة الطلبة في ترجمة النصوص العربية قليلة. هناك مشكلات في قلة تأهل الطلبة في كفاءة الترجمة للنصوص العربية. ظهرت هذة المشكلات بأسباب مختلفة منها عدم الحماسة للمطالعة بتعليمهم. كذلك في طريقة التدريس وهي تعتمد على الإستماع بشرح المدرس ثم يتقدم كل الطلبة لقراءتها وترجمتها. المنهج المستخدم الذي قام به الباحث في هذا البحث هو المنهج التطويري بنموذج Borg And Gall . نتائج تحليل البيانات كما تلي: 1) أما مواصفات الإنتاج فهي شكل الكتاب، مضمون الكتاب، الترجمة، التقويم 2) صلاحية تطوير مواد تعليم الترجمة للنصوص العربية هو من قبل صلاحية خبير المواد وخبير التصميم 3)أما فعالية الإنتاج فهي تعرف فعالية تطوير الإنتاج من خلال تطبيق SPSS ، حيث يتم فحص إدخال البيانات الخاصة بنتائج الاختبار القبلي والبعدي للطلبة. لمعرفة فاعلية الإنتاج ، اختارت الباحثة اختبارًا بنوع الاختبار Sampel Paired Test الذي له الصيغة الأساسية، إذا كانت قيمة sig. 2-tailed أصغر من 0.05 ، وهذا يدل على الفرق الكبير بين الاختبار القبلي والبعدي. بينما كانت البيانات التي حصلت عليها الباحثة 0.00 ، مما يدل على أن قيمة sig. 2-tailed أصغر من 0.05. تظهر نتائج تعليم الطلبة تغييرا إيجابيا كبيرا بعد استخدام الإنتاج التطويري أي كتاب الترجمة للنصوص العربية.
HADITS-HADITS TENTANG KEADILAN GENDER
Authors: Ali Mohtarom  
Published: July 2022

Kata Gender (dibaca jender) berasal dari Bahasa Inggris yang berarti jenis kelamin.[1] Pada umumnya perbedaan laki-laki dan perempuan dari segi seks/jenis kelamin secara biologis ini diistilahkan dengan perbedaan kodrati yang bersifat mutlak tidak bisa ditukar. Perempuan memiliki rahim, payudara, ovarium, haid, hamil dan melahirkan. Sedangkan laki-laki memiliki penis dan sperma untuk pembuahan. Perbedaan ini bersifat alami sepanjang masa dan berlaku bagi semua manusia di manapun berada, tidak pandang kaya miskin, pejabat atau rakyat, perkotaan atau pedesaan. Adapun perbedaan laki-laki dan perempuan yang dihasilkan interpretasi sosial dan simbolik atau social construction, atau perbedaan non kodrati, bisa berubah dari waktu ke waktu, maupun tempat.
Penelitian ini menggunakan metode penelitian kualitatif deskriptif. Penelitian yang ditujukan untuk mendeskripsikan dan menganalisis fenomena, peristiwa, aktifitas sosial, sikap, kepercayaan, persepsi, dan pemikiran orang secara individu maupun secara kelompok
Hadis-hadis tentang gender dalam pembahasan ini adalah disusun berdasarkan pengklasifikasian tersebut dan atau berdasarkan tematiknya, yaitu masalah penciptaan perempuan, mengenai tugas/tanggung jawab suami istri, perihal keutamaan laki-laki, menyangkut kepemimpinan perempuan, serta yang bertalian dengan kemitraan laki-laki dan perempuan.

[1] Echols, John M., Hasan Shadily, 1983,Kamus Inggris Indonesia, Gramedia, Jakarta, hal 265.