bluuebunny/crossref_metadata_2025_split huggingface dataset:
Puercosuchus traverorum n. gen. n. sp.: a new malerisaurine azendohsaurid (Archosauromorpha: Allokotosauria) from two monodominant bonebeds in the Chinle Formation (Upper Triassic, Norian) of Arizona
Authors: Marsh Adam D. , Parker William G. , Nesbitt Sterling J. , Kligman Ben T. , Stocker Michelle R. 
Published: September 2022

AbstractNon-archosaur archosauromorphs are a paraphyletic group of diapsid reptiles that were important members of global Middle and Late Triassic continental ecosystems. Included in this group are the azendohsaurids, a clade of allokotosaurians (kuehneosaurids and Azendohsauridae + Trilophosauridae) that retain the plesiomorphic archosauromorph postcranial body plan but evolved disparate cranial features that converge on later dinosaurian anatomy, including sauropodomorph-like marginal dentition and ceratopsian-like postorbital horns. Here we describe a new malerisaurine azendohsaurid from two monodominant bonebeds in the Blue Mesa Member, Chinle Formation (Late Triassic, ca. 218–220 Ma); the first occurs at Petrified Forest National Park and preserves a minimum of eight individuals of varying sizes, and the second occurs near St. Johns, Arizona. Puercosuchus traverorum n. gen. n. sp. is a carnivorous malerisaurine that is closely related to Malerisaurus robinsonae from the Maleri Formation of India and to Malerisaurus langstoni from the Dockum Group of western Texas. Dentigerous elements from Puercosuchus traverorum n. gen. n. sp. confirm that some Late Triassic tooth morphotypes thought to represent early dinosaurs cannot be differentiated from, and likely pertain to, Puercosuchus-like malerisaurine taxa. These bonebeds from northern Arizona support the hypothesis that non-archosauriform archosauromorphs were locally diverse near the middle Norian and experienced an extinction event prior to the end-Triassic mass extinction coincidental with the Adamanian-Revueltian boundary recognized at Petrified Forest National Park. The relatively late age of this early-diverging taxon (Norian) suggests that the diversity of azendohsaurids is underrepresented in Middle and Late Triassic fossil records around the world.UUID: http://zoobank.org/e6eeefd2-a0ae-47fc-8604-9f45af8c1147.
Use of extracorporeal membrane oxygenation for bronchoscopic removal of a tracheal foreign body in a child
Authors: Harischandra D V T , Jayaweera J M R G , Wickramasinghe A , Firmin R K 
Published: September 2022

AbstractBackgroundBronchoscopic removal of a foreign body is a common emergency procedure in paediatric otolaryngology. It is potentially life-threatening, as complete airway obstruction caused by the foreign body can lead to hypoxic cardiac arrest during the manipulation of the object.Case reportThis paper presents a child who had aspirated a foreign body that could not be extracted conventionally via rigid bronchoscopy in the first instance. Subsequently, it was extracted at repeat bronchoscopy under controlled respiratory conditions maintained by an extracorporeal gas exchange circuit – extracorporeal membrane oxygenation, using a polypropylene hollow fibre oxygenator commonly employed in cardiac surgery (rather than a more expensive polymethyl pentene oxygenator commonly used in extracorporeal membrane oxygenation).ConclusionExtracorporeal membrane oxygenation use can be considered in exceptional cases of upper airway emergencies, even in resource-poor settings, and can avoid more hazardous thoracotomy and bronchotomy procedures.
Nonsurgical periodontal treatment in type II diabetics in a middle-income country: a cost-effectiveness analysis
Authors: Rojas-Gómez Ana M. , Serrano Juan J. , Rosselli Diego 
Published: September 2022

Abstract

Objectives
To evaluate the cost-effectiveness of the nonsurgical periodontal treatment (NSPT) compared with supragingival therapy in type II diabetics with periodontitis.

Methods
A decision tree analysis was used to estimate the costs and health outcomes of two periodontal therapies in a hypothetical cohort of type II diabetics with periodontitis. The analysis was developed from the perspective of a third-party payer at 1 year and 5 years. Probabilities were derived from two systematic reviews. The costs and resource use were validated by a Delphi expert panel. All costs were expressed in USD, using the 25 May 2021 Colombian pesos market exchange rate (USD 1 = COP 3,350).

Results
NSPT was a dominant alternative compared with subsidized supragingival therapy in type II diabetics with periodontitis, generating savings of USD 87 and 400, during the first year or up to 5 years, respectively, and improving dental survival from 32 to 69 percent.

Conclusions
NSPT can generate savings by reducing the complications derived from uncontrolled periodontitis and tooth loss.
Synchronizing words and monoid factorization, yielding a new parameterized complexity class?
Authors: Fernau Henning , Bruchertseifer Jens 
Published: September 2022

AbstractThe concept of a synchronizing word is a very important notion in the theory of finite automata. We consider the associated decision problem to decide if a given DFA possesses a synchronizing word of length at most k, where k is the standard parameter. We show that this problem DFA-SW is equivalent to the problem Monoid Factorization introduced by Cai, Chen, Downey, and Fellows. Apart from the known
$\textsf{W}[2]$
-hardness results, we show that these problems belong to
$\textsf{A}[2]$
,
$\textsf{W}[\textsf{P}],$
and
$\textsf{WNL}$
. This indicates that DFA-SW is not complete for any of these classes, and hence, we suggest a new parameterized complexity class
$\textsf{W}[\textsf{Sync}]$
as a proper home for these (and more) problems. We present quite a number of problems that belong to
$\textsf{W}[\textsf{Sync}]$
or are hard or complete for this new class.
Biogeochemical Responses to Mixing of Glacial Meltwater and Hot Spring Discharge in the Mount St. Helens Crater
Authors: Dubnick A. , Faber Q. , Hawkings J. R. , Bramall N. , Christner B. C. , Doran P. T. , Nadeau J. , Snyder C. , Kellerman A. M. , McKenna A. M. , Spencer R. G. M. , Skidmore M. L. 
Published: September 2022

AbstractEnvironments where geothermal waters and glacier meltwater mix are common on Earth yet little is known about the biogeochemical processes that occur when hot, reduced geothermal water mixes with cold, oxidized glacial meltwater in natural systems. Mount St. Helens provides an ideal location to study the interaction between geothermal and glacier waters since the water sources, and their mixing environment in Step Creek, are exposed in the volcanic crater. We find that the two water sources contain distinct major ion, trace element, dissolved organic matter (DOM), and biological signatures. The hot spring contains high concentrations of biogeochemically reactive components (e.g., siderophile and chalcophile trace elements and DOM) compared to the glacier discharge but a large fraction of these solutes do not remain in solution after the waters mix. In contrast, glacier discharge contains fewer solutes but most of these solutes remain in solution after the waters mix. The mixing of glacier and hot spring water in Step Creek supports seston and benthic ecosystems that have higher phototrophic and microbial biomass than those in the source waters, suggesting that the mixing environment in this high‐gradient stream provide a more comprehensive suite of soluble and essential nutrients that promote primary production and DOM cycling.
Acoustic transmissive cloaking with adjustable capacity to the incident direction
Authors: Lian Meng , Duan Linqiu , Chen Junjie , Jia Jingyuan , Su Ying , Cao Tun 
Published: September 2022

AbstractZero-refractive-index (ZRI) phononic crystals (PhCs), in which acoustic waves can be transmitted without phase variations, have considerable potential for engineering wavefronts and thus are applicable to invisibility cloaking. However, the creation of the transmissive cloaking achieved by ZRI-PhCs is challenging under an oblique incidence, which substantially hinders their practical applications. Here, we experimentally demonstrate acoustic transmissive cloaking with the adjustable capacity to the incident direction. Acoustic transmissive cloaking of arbitrarily shaped obstacles can be obtained through a hybrid acoustic structure consisting of one outer layer of a programmable phase-engineered metasurface (PPEM) and one inner layer of a double zero-refractive-index (DZRI)-PhC. The DZRI-PhC is functionally the same as an equiphase area and can guide acoustic waves around the obstacle, a process known as acoustic tunneling. The PPEM perpendicularly transfers the incident acoustic waves to the DZRI-PhC and allows the emergent waves from the DZRI-PhC to transmit along the original incident direction. The DZRI-PhC is made of an array of iron squares in the air. The reciprocal of the effective bulk modulus and the effective mass density is approximately zero at a frequency of 3015 Hz (0.5187 v0/a) originating from the zeroth-order Fabry–Pérot (FP) resonance that possesses infinite phase velocities. Each meta-atom of the outer metasurface consists of a line channel and four shunted Helmholtz resonators, which have effective masses that are engineered by a mechanics system. The amplitude and phase of the sound waves propagating through each meta-atom can be controlled continuously and dynamically, enabling the metasurface to obtain versatile wavefront manipulation functions. Acoustic cloaking is visually demonstrated by experimentally scanning the acoustic field over the hybrid structure at a frequency of 3000 Hz (0.5160 v0/a). Our work may provide applications with great potential, including underwater ultrasound, airborne sound, acoustic communication, imaging, etc.
A protein-based cGAS-STING nanoagonist enhances T cell-mediated anti-tumor immune responses
Authors: Wang Xuan , Liu Yingqi , Xue Chencheng , Hu Yan , Zhao Yuanyuan , Cai Kaiyong , Li Menghuan , Luo Zhong 
Published: September 2022

AbstractcGAS-STING pathway is a key DNA-sensing machinery and emerges as a promising target to overcome the immunoresistance of solid tumors. Here we describe a bovine serum albumin (BSA)/ferritin-based nanoagonist incorporating manganese (II) ions and β-lapachone, which cooperatively activates cGAS-STING signaling in dendritic cells (DCs) to elicit robust adaptive antitumor immunity. Mn2+-anchored mannose-modified BSAs and β-lapachone-loaded ferritins are crosslinked to afford bioresponsive protein nanoassemblies, which dissociate into monodispersive protein units in acidic perivascular tumor microenvironment (TME), thus enabling enhanced tumor penetration and spatiotemporally controlled Mn2+ and β-lapachone delivery to DCs and tumor cells, respectively. β-lapachone causes immunogenic tumor cell apoptosis and releases abundant dsDNA into TME, while Mn2+ enhances the sensitivity of cGAS to dsDNA and augments STING signaling to trigger downstream immunostimulatory signals. The cGAS-STING nanoagonist enhances the tumor-specific T cell-mediated immune response against poorly immunogenic solid tumors in vivo, offering a robust approach for immunotherapy in the clinics.
A hygroscopic nano-membrane coating achieves efficient vapor-fed photocatalytic water splitting
Authors: Suguro Takuya , Kishimoto Fuminao , Kariya Nobuko , Fukui Tsuyoshi , Nakabayashi Mamiko , Shibata Naoya , Takata Tsuyoshi , Domen Kazunari , Takanabe Kazuhiro 
Published: September 2022

AbstractEfficient water vapor splitting opens a new strategy to develop scalable and corrosion-free solar-energy-harvesting systems. This study demonstrates highly efficient overall water splitting under vapor feeding using Al-doped SrTiO3 (SrTiO3:Al)-based photocatalyst decorated homogeneously with nano-membrane TiOx or TaOx thin layers (<3 nm). Here, we show the hygroscopic nature of the metal (hydr)oxide layer provides liquid water reaction environment under vapor, thus achieving an AQY of 54 ± 4%, which is comparable to a liquid reaction. TiOx coated, CoOOH/Rh loaded SrTiO3:Al photocatalyst works for over 100 h, under high pressure (0.3 MPa), and with no problems using simulated seawater as the water vapor supply source. This vapor feeding concept is innovative as a high-pressure-tolerant photoreactor and may have value for large-scale applications. It allows uniform distribution of the water reactant into the reactor system without the potential risk of removing photocatalyst powders and eluting some dissolved ions from the reactor.
Single-stage tubular and multistage planar systems of passive permeate-side-heated solar membrane distillation
Authors: Sujon Shahin Ahmed , Yi Peng 
Published: September 2022

AbstractScarcity of drinking water is a global problem and especially serious in rural areas of developing countries. Passive permeate-side-heated interfacial-heating solar membrane distillation has been shown recently as a promising system for off-grid distributed water and wastewater treatment. In this study, single-stage tubular systems were developed by giving the poly(vinylidene fluoride) (PVDF) membrane (pore size: 0.45 µm) a tubular structure with the outer surface (i.e., the permeate side) coated with carbon black NPs which absorbed solar thermal energy and evaporated the feedwater inside the membrane tube. Under natural sunlight, the vertical tubular system had a production rate of distilled water per footprint of 0.67‒2.06 kg m−2 day−1 throughout the year, 71% higher than the single-stage planar system on average. The three-stage planar systems were developed by overlapping three single-stage modules. Two adjacent modules shared a common copper sheet that serves as both the top of the condensation chamber of the preceding stage and the bottom of the feedwater chamber of the following stage. The copper sheet can partially transfer the condensation heat of the preceding stage to the feedwater of the following stage, thus enhancing the system energy efficiency (ƞsys) in producing distilled water. The ƞsys and distillate flux of the three-stage systems were 62% and 5.01 kg m−2 day−1, respectively, at the average daytime irradiance of 422 W m−2, 34% higher than the single-stage planar systems.
SARS-COV-ATE risk assessment model for arterial thromboembolism in COVID-19
Authors: Li Pin , Lee Yi , Jehangir Qasim , Lin Chun-Hui , Krishnamoorthy Geetha , Sule Anupam A. , Halabi Abdul R. , Patel Kiritkumar , Poisson Laila , Nair Girish B. 
Published: September 2022

AbstractPatients with SARS-CoV-2 infection are at an increased risk of cardiovascular and thrombotic complications conferring an extremely poor prognosis. COVID-19 infection is known to be an independent risk factor for acute ischemic stroke and myocardial infarction (MI). We developed a risk assessment model (RAM) to stratify hospitalized COVID-19 patients for arterial thromboembolism (ATE). This multicenter, retrospective study included adult COVID-19 patients admitted between 3/1/2020 and 9/5/2021. Among 3531 patients from the training cohort, 15.5% developed acute in-hospital ATE, including stroke, MI, and other ATE, compared to 13.4% in the validation cohort. The 16-item final score was named SARS-COV-ATE (Sex: male = 1, Age [40–59 = 2, > 60 = 4], Race: non-African American = 1, Smoking = 1 and Systolic blood pressure elevation = 1, Creatinine elevation = 1; Over the range: leukocytes/lactate dehydrogenase/interleukin-6, B-type natriuretic peptide = 1, Vascular disease (cardiovascular/cerebrovascular = 1), Aspartate aminotransferase = 1, Troponin-I [> 0.04 ng/mL = 1, troponin-I > 0.09 ng/mL = 3], Electrolytes derangement [magnesium/potassium = 1]). RAM had a good discrimination (training AUC 0.777, 0.756–0.797; validation AUC 0.766, 0.741–0.790). The validation cohort was stratified as low-risk (score 0–8), intermediate-risk (score 9–13), and high-risk groups (score ≥ 14), with the incidence of ATE 2.4%, 12.8%, and 33.8%, respectively. Our novel prediction model based on 16 standardized, commonly available parameters showed good performance in identifying COVID-19 patients at risk for ATE on admission.
V-set and immunoglobulin domain containing 1 (VSIG1) as an emerging target for epithelial–mesenchymal transition of gastric cancer
Authors: Satala Catalin-Bogdan , Jung Ioan , Kovacs Zsolt , Stefan-Van Staden Raluca-Ioana , Molnar Calin , Bara Tivadar , Patrichi Andrei-Ionut , Gurzu Simona 
Published: September 2022

AbstractV-set and Immunoglobulin domain containing 1 (VSIG1) is a cell–cell adhesion molecule which role in the genesis and evolution of gastric cancer (GC) is not understood. Only three Medline-indexed papers have focused on the role of VSIG1 in GC. The clinicopathological features of 94 GCs were examined in association with immunohistochemical (IHC) patterns of VSIG1, E-cadherin, and β-catenin which were assessed in the tumor core (central) vs. invasive edge. Cases were classified depending on the VSIG1 expression: membrane/membrane in both core and invasive front; null/negative staining in both core and invasive front; and cases with translocational patterns: membrane core/cytoplasmic buds and cytoplasmic core/null buds. Most of the tumors showed null pattern (n = 54). Cases with translocational patterns (n = 20) were GCs with a high lymph node ratio value (≥ 0.26) and advanced Dukes-MAC-like stage. Of the 20 total cases, 9 showed membrane-to-nuclear translocation of β-catenin and loss of E-cadherin, as indicators of epithelial–mesenchymal transition. All cases with membrane/membrane pattern (n = 20) involved the distal stomach. The poorest overall survival was registered in patients with subcellular translocation of VSIG1, compared to those with either membrane/membrane or null patterns (p = 0.002). In GC, VSIG1 acts as an adhesion membrane protein but its membrane-cytoplasmic translocation can be an indicator of epithelial–mesenchymal transition due to cytoplasmic VSIG1-mediated activation of canonical Wnt/β-catenin signaling pathway.
Efficiency of the traditional practice of traps to stimulate black truffle production, and its ecological mechanisms
Authors: Taschen E. , Callot G. , Savary P. , Sauve M. , Penuelas-samaniego Y. , Rousset F. , Parlade X. , Selosse M.-A. , Richard F. 
Published: September 2022

AbstractThe black truffleTuber melanosporumwas disseminated all over the world, propelled by the development of a wide variety of empirical practices. A widespread practice, called ‘truffle trap’, consists of placing pieces of truffles into excavations dug under host trees, and of collecting truffle in these traps in the next years. This research aims at (1) evaluating the effect of this practice on fruitbody production based on the analysis of 9924 truffle traps installed in 11 orchards acrossT. melanosporumnative area in France and (2) exploring the mechanisms involved in fruitbody emergence using traps where the genotypes of introduced truffles were compared with those of fruitbodies collected in the same traps. We confirmed that truffle traps provide a major and highly variable part of truffle ground production, representing up to 89% of the collected fruitbodies. We evidenced a genetic link between introduced spores and collected fruitbodies, and then demonstrated that truffle growers provide paternal partners for mating with local maternal mycelia. We also highlighted that soil disturbance stimulate the vegetative development of established maternal mycelia. This research supports that a widely used traditional practice enhances fruitbody production by shaping favorable conditions and providing sexual partners required for fruiting.
Time to castration resistance is a novel prognostic factor of cancer-specific survival in patients with nonmetastatic castration-resistant prostate cancer
Authors: Hakozaki Yuji , Yamada Yuta , Kawai Taketo , Nakamura Masaki , Takeshima Yuta , Iwaki Takuya , Teshima Taro , Kinoshita Yoshitaka , Fujii Yoichi , Akiyama Yoshiyuki , Sato Yusuke , Yamada Daisuke , Suzuki Motofumi , Kashiwagi-Hakozaki Mayu , Ushiku Tetsuo , Kume Haruki 
Published: September 2022

AbstractWe aimed to identify prognostic factors of cancer-specific survival (CSS) in non-metastatic castration-resistant prostate cancer (M0CRPC) patients. The final analysis of this retrospective cohort included 82 patients who were diagnosed as M0CRPC between 1998 and 2018 at the University of Tokyo Hospital. CRPC was defined as prostate-specific antigen (PSA) progression (increased PSA ≥ 25% and ≥ 2 ng/mL above the nadir or detection of a metastatic lesion). The median value of age and PSA at the time of CRPC were 76 (range 55–94) years and 2.84 (range 2.04–22.5) ng/mL, respectively. The median follow-up time from CRPC diagnosis was 38 (range 3–188) months. The prognostic factors of CSS were ‘PSA doubling time (PSADT) ≤ 3 months’, ‘time to CRPC diagnosis from the start of androgen deprivation therapy (TTCRPC) ≤ 12 months’, of which TTCRPC was a novel risk factor of CSS. In the multivariate analysis, ‘PSADT ≤ 3 months’ and TTCRPC ≤ 12 months’ remained as statistically significant predictors of CSS. Novel risk stratification was developed based on the number of these risk factors. The high-risk group showed a hazard ratio of 4.416 (95% confidence interval 1.701–11.47, C-index = 0.727).
Thermal micropolar and couple stresses effects on peristaltic flow of biviscosity nanofluid through a porous medium
Authors: Ismael Aya M. , Eldabe Nabil T. , Abou zeid Mohamed Y. , El Shabouri Sami M. 
Published: September 2022

AbstractThe main aim of the current study is to analyze couple stresses effects on MHD peristaltic transport of a micropolar non-Newtonian nanofluid. The fluid flows through a porous media between two horizontal co-axial tubes. The effects of radiation, chemical reaction, viscous and ohmic dissipation are considered. The inner tube is solid and uniform, while the outer tube has a sinusoidal wave traveling down its wall. The governing equations have been simplified using low-Reynolds number and long wave-length approximations, thus a semi-analytical solutions have been obtained using the homotopy perturbation method. Numerical results for the behaviors of the axial velocity, microrotation velocity, temperature and nanoparticles concentration with the physical parameters are depicted graphically through a set of graphs. Furthermore, the values of the skin friction coefficient, Nusselt and nano Sherwood numbers are computed and presented graphically through some draws. Moreover, the trapping phenomenon is discussed throughout a set of figures. The present study is very important in many medical applications, as the gastric juice motion in the small intestine when an endoscope is inserted through it. Further, gold nanoparticles are utilized in the remedy of cancer tumor.