bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiological and clinical characteristics of pertussis in children and their close contacts in households: A cross-sectional survey in Zhejiang Province, China
Authors: Lin Luo-Na , Zhou Jin-Si , Hua Chun-Zhen , Bai Guan-Nan , Mi Yu-Mei , Zhou Ming-Ming 
Published: August 2022

BackgroundDespite the expanded immunization programs, the “re-emergence of pertussis” has become a global concern in recent years. At present, the prevalence of pertussis in China is seriously underestimated, and the role of close contact on the disease spreading in children remains unclear.ObjectivesOur study aimed to investigate pertussis’s epidemiological and clinical characteristics in children and their close contacts in households, as well as the antimicrobial resistance of Bordetella pertussis (B. pertussis) in Zhejiang Province, China.MethodsWe have collected the retrospective and prospective data of children who were suspected of pertussis and their close contacts in households from January 1, 2018, to December 31, 2020, in the Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Nasopharyngeal swabs were collected and cultured for B. pertussis. Antibiotics susceptibility test was determined by using E-test methods. Clinical information was collected from the medical records systems.ResultsA total of 350 index patients and their 946 family members (close contacts in households) from 350 families were recruited. B. pertussis strains were isolated from 130 (37.1%) index patients and 116 (12.3%) close contacts. 37 index patients had negative culture results for B. pertussis while their close contacts were positive. A higher positive rate was found in female adults than that in male adults (16.3% vs. 5.1%, P &lt; 0.01). The positive rate in index patients from multi-child families was significantly higher than that from one-child families (51.7% vs. 37.7%, P &lt; 0.05). 53.3% of the pertussis patients were under 6 months of age. 98 (75.4%) isolates had MICs ≥ 256 mg/L to erythromycin, azithromycin, and clindamycin, and 127 (97.7%) had MICs &lt; 0.016 mg/L to piperacillin.ConclusionInfants under 6 months of age are at high risk of pertussis, and close contacts in households are prone to cluster infection. Culture for B. pertussis both in children and their close contacts contributes to improving the diagnosis rate of pertussis in children. Isolates of B. pertussis in China are highly resistant to macrolides.
Case report: Five patients with myocarditis after mRNA COVID-19 vaccination
Authors: Murase Hiroki , Zhu Yiqing , Sakaida Keiya , Mizuno Hayato , Mori Hiromitsu , Iwayama Hideyuki , Suzuki Noriyuki , Nagai Noriko , Okumura Akihisa 
Published: August 2022

ObjectivesTo describe clinical features and laboratory data of myocarditis after the mRNA COVID-19 vaccine in children.MethodsWe reviewed patients younger than 18 years of age, who visited our hospital because of myocarditis within 1 week after BNT162b2 from June 2021 to January 2022.ResultsWe identified five male patients aged 12–16 years who presented to our hospital with myocarditis within 2–3 days after the second dose of BNT162b2 COVID-19 vaccination between June 2021 and January 2022. All patients experienced chest pain, and fever, pain other than chest pain, and shortness of breath were present in two, three, and two patients, respectively. The serum troponin I level was increased in all patients except one, and electrocardiogram (ECG) showed ST elevation in all patients. Echocardiography revealed pericardial effusion and decreased ejection fraction in three and one patients, respectively. In accordance with the Japanese guidelines for myocarditis, the patients were treated with colchicine and aspirin. Chest pain improved within a few days with no hemodynamic instability. The patients were discharged with no sequelae.ConclusionsST changes on ECG and elevated troponin I levels may aid the diagnosis of myocarditis after mRNA COVID-19 vaccination
Policies of voluntary services involved in public health emergencies in China: Evolution, evaluation, and expectation
Authors: Chen Hongli , Wang Jing , Yu Xiaohong , Li Cheng , Zhao Yue , Xing Ying , Li Xianwen 
Published: August 2022

BackgroundPublic health emergencies have an immense effect on social stability, economic development, and human life. Volunteers played an indispensable role in health monitoring, assistance with daily life, and social network repairing. However, few policies analysis concentrated on the voluntary services involved in public health emergencies.ObjectivesThis study aims to analyze and summarize the advantages and flaws of the policy documents relating to voluntary services involved in public health emergencies, and put forward the enlightenment on policymaking and optimization.MethodsA three-dimensional analysis framework of “Policy instruments—Participants of voluntary services—Stages of voluntary services” was designed. Policy documents at the national level were retrieved from the official websites of the State Council of the People's Republic of China and its departments as well as the PKULAW Database. NVivo software was applied to analyze the contents of the included policy documents. Gephi software was adopted to conduct a visualized atlas analysis of the cooperative network among policymaking departments.ResultsA total of 77 policy documents were included, and most were published in 2020 (n = 40). The Ministry of Civil Affairs (n = 19) and the National Health Commission (n = 18) issued more documents than the other departments. They cooperated more extensively with other departments. In policy documents, supply-side policy instruments were utilized the most (65.4%), followed by demand-side (23.9%). Voluntary organizations in the form of ambiguous sense were most mentioned as service participants (n = 73). In the stages of service delivery, service content mainly involved the prevention and control of public health emergencies (27, 18.9%) and psychological counseling (26, 18.2%).ConclusionTime distribution of policy documents featured “incubation period—outbreak and continuous evolution period—elimination recovery period.” Joint issuing became the dominant form. The internal structure of policy instruments was unbalanced with different priorities, and the overall structure is expected to be optimized to promote voluntary organization management, reinforce external resources, and close the gap between policymaking and policy implementation. Volunteers' competence and voluntary organizations' system needs to be improved, and the contents of voluntary services should be enriched for the preparedness for future public health emergency.
Sleep pattern in relation to recurrent osteoporotic fracture in the elderly
Authors: Li Likang , Zeng Haobin , Zhang Bo , Xu Xu , Chen Maoshui , Li Guowei 
Published: August 2022

BackgroundPrevious studies assessed the relationship between individual sleep behavior and fracture risk, rather than taking into account the joint complexity of the sleep behaviors. We aimed to explore the association between sleep pattern and risk of imminent recurrent osteoporotic fracture in older hospitalized patients due to an index osteoporotic fracture, where sleep pattern was evaluated as a combination incorporating five common sleep behaviors (i.e., insomnia, snoring, nocturnal sleep duration, daytime napping, and midnight waking up).MethodsWe used data from a prospective cohort study for analyses. Patients who aged not &lt; 55 years and were admitted to the hospital due to an index osteoporotic fracture were recruited. Sleep pattern was grouped as healthy, intermediate, and poor pattern, based on the categorization of overall sleep scores. We used Cox proportional hazard models to explore sleep pattern in relation to imminent recurrent fracture.ResultsWe included a total of 185 elderly hospitalized patients for analyses with mean (± standard deviation) age = 71.5 ± 10.3 years and 87.0% female. During a mean follow-up of 14.7 months, there were 10 (5.4%) recurrent osteoporotic fractures observed. A significantly higher overall sleep score was found in patients with recurrent fractures when compared with those without fractures (3.20 vs. 2.36, p = 0.038). Both intermediate (p = 0.76) and poor sleep patterns (p = 0.093) were non–significantly associated with an elevated risk of fracture when compared with a healthy pattern. Per-one-increase in the overall sleep score was significantly related to an increased risk of fracture: hazard ratio = 1.60 (95% confidence interval: 1.00-−2.55) from the multivariable model.ConclusionPer-one-increase in the overall sleep score was found to be significantly associated with a 60% higher risk of imminent recurrent osteoporotic fracture in the elderly, and intermediate and poor sleep patterns were non–significantly related to an increased risk of recurrent fracture. More high-quality evidence is required to further evaluate the relationship between the sleep pattern and the risk of recurrent osteoporotic fracture in the elderly.
“Oral health as an important milieu for social and mental health”: Perspectives of adolescents emerging from a qualitative study
Authors: Lawal Folake Barakat , Fagbule Omotayo Francis , Lawal Taiwo Akeem , Oke Gbemisola Aderemi 
Published: August 2022

BackgroundRecent evidence showed that the prevalence of oral diseases is still high among adolescents in many developing countries, including Nigeria. It therefore has becomes pertinent to focus on appropriate oral health interventions to promote oral health among them. This necessitates investigating the perspectives of adolescents, who are the major stakeholders, on the importance of oral health as baseline data needed in planning appropriate primary interventions.AimThe aim of the study was to explore the perspectives of adolescents on the importance of oral health.MethodsAn explorative qualitative study was conducted among adolescents attending senior secondary school I (grade 10) in the metropolis of Ibadan, Nigeria. A total of 12 focus group discussions were conducted among 120 adolescents aged 14 to 19 years. The discussions were transcribed verbatim, and triangulation and organization, as well as thematic analysis, of data were carried out.ResultsSome adolescents had positive perceptions of oral health and valued it as highly important, although some had contrary views and believed oral health was unimportant. Oral health is described as being integral to general health, is associated with eating and communication, is a means of survival and confidence building, and is a prelude to attract the opposite gender. Adolescents perceived the need for oral health education and dental treatment.ConclusionAdolescents have mixed perspectives on the importance of oral health; while some valued it as highly important, others believed it was of no significance. Those who valued oral health as important described it as a milieu for general health, human survival, and social and mental health and thus requested for oral health promotion in schools.
Analisis Kinerja Pegawai di Biro Humas dan Keprotokolan Sekretariat Daerah Provinsi Sumatera Utara
Authors: Rizkasari Susanti , Kardhinata Harso , Isnaini Isnaini 
Published: August 2022

The research objectives are: To analyze the performance of employees and the barriers in the Public Relations and Protocol Bureau of the Regional Secretariat of North Sumatra Province. This type of research is qualitative in accordance with the formulation and research objectives. The results of research on employee performance in the Public Relations and Protocol Bureau of the Regional Secretariat of North Sumatra Province. Showing that the performance in terms of quantity and quality has been going well, this shows that employees are capable of achieving performance. Performance in terms of discipline that the implementation of work discipline starting from the presence of electronic attendance, morning apples and the use of official uniforms, there are still employees who commit violations of work discipline, especially during working hours where it is not optimal to carry out obligations with indicators complying with the provisions of working hours. This can be seen from the presence of employees who do not comply with the provisions of working hours, such as employees who often do not come to work, enter and leave the agency not according to regulations and are often late for office. Performance in terms of initiative that in carrying out their duties, employees always help each other with co-workers in completing tasks without any orders from superiors. Performance in terms of responsibility that employees are able to complete tasks properly in accordance with the specified time but on the one hand the discipline of employee performance is still not optimal.
Prevalência de <em>Mansonella Ozzardi</em> em populações Ribeirinhas do Rio Madeira, Humaitá, Amazonas
Authors: Pereira Antonieta Relvas , Gois Rosineide Vieira , Da Silva Sabrina Carvalho , Basano Sérgio de Almeida , Dos Santos Alcione Oliveira , Camargo Luís Marcelo Aranha 
Published: August 2022

A Mansonella ozzardi é uma filária humana que tem como vetor dípteros simulídeos e é amplamente distribuída na Amazônia. No Brasil esse parasito foi observado pela primeira fez em uma pesquisa nacional da ocorrência de filariose linfática na cidade de Manaus, Amazonas em 1949. Não há informações sobre a ocorrência de casos de mansonelose no município de Humaitá. Com o objetivo de determinar a prevalência de M. ozzardi em populações que residem em áreas ribeirinhas, ao longo do Rio Madeira, no Amazonas, foi realizado um estudo epidemiológico de prevalência nessa população. Foram examinados 183 moradores às margens dos rios Madeira, através da técnica da gota espessa de sangue, onde retirou-se aproximadamente 60 µL de sangue, sem uso de anticoagulante. Em seguida, foi feito a gota espessa de sangue. Transcorridas 5 a 10 horas, fez-se a desemoglobinização, corou-se com Giemsa e visualizou-se ao microscópio com aumento de 10 x e 40x. Não foram encontrados indivíduos infectados com M. ozzardi neste estudo. Este fato pode ser explicado pela técnica diagnóstica utilizada no estudo ser de baixa sensibilidade, ou até mesmo a existência de pacientes com baixas microfilaremias. Estudos futuros com técnicas diagnósticas mais sensíveis podem ajudar a esclarecer esta questão.
Quem defende a criança queer?
Authors: Preciado Beatriz , Marcondes Nogueira Fernanda Ferreira 
Published: August 2022

Neste texto, Beatriz Preciado disserta sobre o modo como as crianças são moldadas no cerne das instituições e, ao mesmo tempo, traça uma crítica mordaz à forma como a sociedade contemporânea controla os corpos desses sujeitos. Indispensável para pesquisadoras e pesquisadores das ciências sociais e humanas, o texto em questão foi gentilmente cedido pela revista francesa Libération, onde foi originalmente publicado, e traduzido por Fernanda Nogueira.
O "desenho de arquiteto" de João Cabral de Melo Neto
Authors: Cardeal Rafaela 
Published: August 2022

Resumo: Tomando como ponto de partida a metáfora “desenho de arquiteto”, este ensaio aborda os aspectos arquitetônicos da poesia de João Cabral de MeloNeto. Para tal, propõe uma leitura retrospectiva da obra até o livro A educação pela pedra (1966), considerado pela crítica o mais arquitetônico da produçãocabralina.
Palavras-chave: João Cabral de Melo Neto; desenho de arquiteto; Le Corbusier; poesia brasileira.
___________________Abstract: Taking the metaphor of the “architectural blueprint” as a starting point, this paper approaches the architectural aspects of João Cabral de Melo Neto’s poetry. For this purpose, it proposes a retrospective reading of his works until the book A educação pela pedra, considered by critics João Cabral’s most architectural deed.
Keywords: João Cabral de Melo Neto; architectural blueprint; Le Corbusier; Brazilian poetry
Fusão mítica: o descenso de Orfeu aos infernos em "Onde andará Dulce Veiga?", de Caio Fernando Abreu
Authors: Lugo Farides María 
Published: August 2022

Resumo: Pretendemos mostrar como a figura mitológica do descenso de Orfeu aos infernos, em busca de sua amada Eurídice, tem núcleo na narrativa Onde andará Dulce Veiga?: Um romance B, de Caio Fernando Abreu. Mito clássico e romance estão fazendo uma fusão mítica, na qual o primeiro pode complementar a leitura analítica do segundo. Nesta pesquisa apresentaremos as coincidências entre os dois textos, com o objetivo de atingir uma interpretação válida e adequada do romance de Caio F., tudo isso tendo como base teórica a linha mitocrítica proposta por Gilbert Durand.
Palavras-chave: Descenso de Orfeu, Onde andará Dulce Veiga?: Um romance B, fusão mítica, mitocrítica, Gilbert Durand.
___________________Abstract: We intend to show how the mythological figure of Orpheus's descent into hell in search of his beloved Eurydice, has core in the narrative Whatever happened to Dulce Veiga?, by Caio Fernando Abreu. Classic myth and romance are doing a mythical fusion, in which the first may complement the analytical reading of the second. In this research we present the similarities between the two texts, in order to achieve a valid and proper interpretation of the Caio F’s novel. All the theoretical background is based on Gilbert Durand’s Myth-Criticism.
Keywords: Descent of Orpheus, Whatever happened to Dulce Veiga?, mythical fusion, Myth-Criticism, Gilbert Durand.
A voz da periferia através de Sérgio Vaz
Authors: Corrêa Lara Barreto , Defilippo Juliana Gervason 
Published: August 2022

Resumo: Esta pesquisa tem como objetivo interpretar e analisar alguns poemas do escritor paulista Sérgio Vaz, buscando compreender de que maneira se evidencia a representatividade da periferia brasileira através das diversas vozes presentes em seu corpus poético selecionado. Para além do caráter artístico, de deleite e fruição, presente no texto literário - e, sobretudo no poético - esta pesquisa intenta compreender a poesia como arma de denúncia, de crítica e de expressão diante de uma sociedade cujas vozes dos estabelecidos ainda se sobrepõem e contagiam as vozes dos outsiders. Nobert Elias e John L. Scotson serão as principais referências a respeito de questões sociológicas para discutir conceitos sobre estabelecidos e outsiders.
Palavras-chave: Sérgio Vaz. Literatura brasileira contemporânea. Marginalidade. Periferia. Poesia.
_____________________________Abstract: This research aims at interpreting and analyzing some of the poems of the writer from São Paulo city Sérgio Vaz, thus trying to understand how the Brazilian periphery representativeness is emphasized through different voices present in the author's selected poetic corpus. Besides the artistic character of delight and enjoyment present in the literary text - and above all, in the poetic aspect -, this research objective is to understand poetry as an instrument of accusation, criticism and expression before a society whose voices of the established ones still take over and affect the voices of the outsiders. Nobert Elias eJohn L. Scotson will be the main references to discuss sociological questions and concepts about the established ones and the outsiders.
Keywords: Sérgio Vaz. Contemporary Brazilian Literature. Marginalization. Periphery. Poetry
The Role of CD4+ and CD8+ T Cells in COVID-19 (Corona Virus Disease 2019)
Authors: Hidayat Rachmat , Patricia Wulandari  
Published: August 2022

The SARS-CoV-2 virus mainly acts on lymphocytes, especially CD4+ and CD8+ T cells, Analysis of a subset of lymphocytes may help in screening awal critical course of the disease. Pincrease of proinflammatory cytokines and chemokines, and decreased regulatory/regulatory T cells contribute to an excessive inflammatory response (increased cytokine production, cytokine release syndrome) with loss of control over the damaging immune response and increased tissue damage (e.g. in the lungs). Sometimes the body's response to infection becomes very exaggerated. for example, when SARS-CoV-2 enters the lungs, it will trigger an immune response, attracting immune cells to the area to attack the virus, resulting in local inflammation, in some patients, excessive/uncontrolled levels of cytokines will activate more immune cells, causing hyperinflammatory called cytokine storms, is a condition that can harm or kill patients.
Comparison of Immune Response and Immunobiology in COVID-19 (Coronavirus Disease 2019) Mild-Moderate Degree and Severe Degree
Authors: Hidayat Rachmat , Patricia Wulandari  
Published: August 2022

The difference in immunological profiles between mild-moderate and severe cases of COVID-19 can be seen in lower lymphocyte counts, leukocytes, and higher neutrophil-lymphocyte ratios. And lower percentages of monocytes, eosinophils, and basophils in severe COVID-19 cases. Proinflammatory cytokines such as TNF-α, IL-1, and IL-6, as well as IL-8 and infection markers such as procalcitonin, ferritin, and C-reactive protein, were also found to be higher in severe clinical cases. T Helper, T suppressor, and T regulatory were found to be decreased in COVID-19 patients with lower numbers of T helper and T regulatory in severe cases.
Perilaku Penggunaan Antibiotik di Masyarakat
Authors: Wulandari Ainun , Rahmawardany Claudia Y 
Published: August 2022

A
Antibiotik merupakan obat untuk untuk mengobati infeksi yang disebabkan oleh bakteri. Pemberian antibiotik pada penderita penyakit infeksi bertujuan untuk menghambat pertumbuhan maupun membunuh bakteri penyebab penyakit, akan tetapi jika penggunaan antibiotik tidak tepat akan mengakibatkan resistensi antibiotik. Oleh karena itu, penelitian ini bertujuan untuk mengetahui bagaimana penggunaan antibiotik pada masyarakat dan hubungan pengetahuan terhadap penggunaan antibiotik. Penelitian ini termasuk penelitian observasional deskriptif dengan pengambilan data dilakukan secara cross sectional menggunakan alat bantu kuesioner. Sampel yang digunakan dalam penelitian ini berjumlah 106 responden. Hasil penelitian menunjukkan responden yang paling banyak menggunakan antibiotik berjenis kelamin perempuan 63 (59,4%), pada rentang usia 17-23 tahun 54 (54,7%). Responden mendapatkan antibiotik dengan menggunakan resep sebanyak 80 (76,2%), apotek sebagai tempat membeli antibiotik 60 (56,6%) terbanyak, dan Amoxicillin jenis antibiotik yang paling banyak digunakan 83 (87,3%). Tingkat pengetahuan masyarakat mengenai penggunaan antibiotik dalam kategori cukup sebanyak 52 (49%) dan perilaku penggunaan antibiotik juga berada dalam kategori cukup sebanyak 73 (68,9%). Terdapat hubungan antara pengetahuan terhadap perilaku penggunaan antibiotik di masyarakat p-value (0,04) < 0,05 (0,04).