bluuebunny/crossref_metadata_2025_split huggingface dataset:
INFLUENCE OF METABOLIC THERAPY ON LIFE QUALITY IN PATIENTS WITH ATRIAL FIBRILLATION PAROXYSMS
Authors: Fushtey I. M. , Podsevahina S. L. , Palamarchuk A. I. , Chabanna E. S. 
Published: November 2022

Abstract. The goal of the study was to investigate the effect of magnesium orotate as a part of complex therapy in sinus rhythm restoring in patients with AF paroxysm, as well as to evaluate its effectiveness and effect on LQo with long-term use.
Materials and research methods. We examined 56 patients (16 women and 40 men) with an average age of (61,5 ± 4,3) years with paroxysmal atrial fibrillation. All patients were divided into two groups. Patients of the 1st group (n=28) underwent medical cardioversion with amiodarone and magnesium orotate. Patients of the 2nd group (n=28) received only amiodarone. The time of sinus rhythm restoration, parameters of electrical instability of the atrial and ventricular myocardium after sinus rhythm restoration, patients life quality 3 months after discharge - were assessed in both groups.
Results. The study allowed to reveal that the addition of magnesium orotate to the basic therapy of patients with atrial fibrillation increases the effectiveness of medical cardioversion and reduces the time of its onset. When using amiodarone and magnesium orotate, signs of electrical instability of the atrial myocardium (the number of paired and supraventricular extrasystoles) are significantly less according to the results of Holter electrocardiogram monitoring compared with amiodarone monotherapy. Atrial fibrillation caused a life quality parameters deviations in the form of an increase in the severity of the disease symptoms, physical activity limitation and psycho-emotional sphere disorders. 3 months after the treatment, it was noted that life quality in patients of the 1st group (complex therapy using magnesium orotate) was higher compared to patients of the 2nd group due to the improvement in the indicators of the "psycho-emotional" component.
Conclusions. The addition of magnesium orotate to the basic therapy of paroxysmal atrial fibrillation can significantly improve the clinical course of the disease in patients and their life quality after 3 months treatment period.
STIMULATION OF THE WOUND PROCESS IN LONG-TERM UNHEALED WOUNDS IN PATIENTS WITH DIABETIC FOOT SYNDROME
Authors: Militsa M. M. , Soldusova V. V. , Militsa K. M. , Steblyanko V. V. , Kazakov V. S. , Postolenko M. D. 
Published: November 2022

The purpose of the work. Compare the effectiveness of PRP and general accepted methods of local therapy for long-term unhealed wounds in patients with diabetic foot syndrome.
Materials and methods. A study was performed in 33 long-term patients unhealed wounds on the foot and leg in the neuropathic form of diabetic foot syndrome. Patients were divided into two groups depending on the nature of the received therapies - PRP and local therapy according to generally accepted principles. The effectiveness of therapy was assessed by the nature of changes in the microflora and c wound cell composition, as well as wound surface area on the 1st day, 8th and 22nd after starting treatment.
Results. The use of PRP allowed to observe on the 8th day regenerative-inflammatory type of cytogram, have manifestations of vascularization and epithelialization, reduce the number of patients with infected wounds by 2.7 times and reducing the wound surface area by 1.7 cm, which is 3.4 times more than in the second group (0.5 cm). The introduction of the second dose of PRP is even more stimulating reparative changes in the wound, manifested by the regenerative type of cytogram, reducing the number of infected wounds by 8 times, and reducing the area wound surface 2 times from the first measurement, while in the second group only on the 22nd day there were positive changes that were characteristic of the first group on the 8th day.
Conclusion. Thus, the use of PRP in therapy is long unhealed wounds in diabetic foot syndrome, is a promising area of ​​regenerative therapy. PRP is a way to obtain a natural concentration of internal factors of growth with minimal invasiveness and low costs. Proposed method of biological therapy in such patients is simple and affordable for both patient and for the doctor.
STUDY OF THE EFFECT OF CRYOPRESERVED PLACENTA EXTRACT ON THE PROCESSES OF CYTOLYSIS AND LIPID PEROXIDATION IN CCL4-INDUCED LIVER DAMAGE
Authors: Koshurba I. V. 
Published: November 2022

Abstract. The search for new strategies for the correction of exogenous toxic liver lesions is due to the steady increase in the incidence of hepatitis and cirrhosis among the working population, which is an important medical and social problem.
The aim is to determine the effect of cryopreserved placenta extract (CEP) on the state of the liver of rats with tetrachloromethane (CCl4)-induced damage by indicators of lipid peroxidation (LP) and markers of cytolysis.
Materials and methods. Experimental studies were conducted on 28 male rats. Acute CCl4-induced hepatitis was reproduced by a single injection of 50.0% CCl4 oil solution. KEP was administered 1 time per day for 5 days before the introduction of CCl4. The material for the study was whole blood and liver homogenates, in which the content of reactants with thiobarbituric acid (TBA-RP), catalase activity, superoxide dismutase (SOD) activity, alanine aminotransferase (AlAt) and aspartate aminotransferase (AsAt) activity, as well as γ-glutamyl activity were determined. γ-glutamyl transpeptidases (γ-GTP) and alkaline phosphatase (AP) according to standard methods.
Results and discussion. The study showed that the content of TBA-RP in liver homogenates was lower (p<0.01) by 35.6% in rats that were prophylactically injected with CEP compared to rats with simulated CCl4-induced hepatitis without treatment (control group). An increase in the level of catalase (p=0.02) with the use of CEP was established by 33.8% and an increase in the activity of SOD (p<0.01) by 45.5% compared to the indicators of rats in the control group. It is also shown that the level of AlAt after administration of CEP decreased (p<0.001) by 56.0%, the level of AsAt decreased (p<0.001) by 48.6%, the level of γ-HTP decreased by 37.8% compared to the rats with untreated CCl4-induced hepatitis.
Conclusions. Prophylactic five-day administration of CEP leads to the leveling of CCl4-induced LP activation and signs of cytolysis syndrome.
Pelatihan Pemanfaatan Website E-Learning Sebagai Media Pembelajaran Online dengan Content Management System
Authors: Sediyono Eko , A. Hasibuan Zainal , Setyawan Iwan , Purnama Harahap Eka , Darmawan Arif 
Published: November 2022

Saat era pandemic Covid-19 mulai menyerang, beberapa negara dalam pemerintahannya termasuk negara indonesia, sudah membuat rencana untuk mencegah virus, yang mencakup kebijakan menutup sekolah dan mengharuskan siswa untuk menyelesaikan kursus mereka di rumah. Wabah virus Corona telah menimbulkan banyak kekhawatiran, ketakutan, bahkan banyak menimbulkan banyak korban jiwa. Masalah utamanya, dikarenakan tidak semua guru dan sekolah dapat dengan cepat dan kompeten dalam melakukan pembelajaran online. Salah satu pendekatannya adalah dengan terlibat dalam proyek pengabdian masyarakat yang mencakup pelatihan tentang bagaimana cara membuat situs web yang berfungsi sebagai alat e-learning untuk pengajaran di kelas maupun di dalam rumah. Hal ini dikarenakan para guru dan sekolah mulai menyadari bahwa di era teknologi informasi, pembelajaran secara online merupakan salah satu sarana yang penting dalam menyampaikan materi pelajaran kepada siswa sekolah. Adapun tujuan kegiatan pengabdian ini adalah untuk meningkatkan kemampuan guru dan sekolah dalam penggunaan media pembelajaran, khususnya media Web-blog. Pelaksanaan kegiatan meliputi tahap persiapan, pertemuan melalui Google Meet, dan tahap pemantauan melalui WhatsApp, pendekatan yang digunakan dalam kegiatan ini adalah metode pelatihan, praktik, dan bimbingan. Hasil dari kegiatan pelatihan ini adalah para guru kini memiliki pengetahuan, kecakapan, dan keterampilan yang lebih dalam mengembangkan website sebagai platform e-learning di sekolah, sebagai sarana meningkatkan kualitas pengajaran di indonesia.
DAMPAK PEMASARAN ONLINE DI ERA COVID-19
Authors: Maulidasari Cut Devi , Damrus Damrus 
Published: November 2022

Seiring dengan perkembangan waktu, teknologi berkembang semakin pesat yang ditandai dengan adanya pemanfaatan internet dan juga media digital. Teknologi dan media digital menjadi salah satu komponen penting bagi para pelaku usaha dalam memasarkan produknya secara online. Pemasaran online (Internet Marketing/E-Marketing) dinilai lebih menguntungkan dikarenakan dapat menjangkau calon konsumen/pelanggan potensial dalam cakupan yang luas tanpa batasan ruang dan waktu dengan biaya pemasaran yang lebih murah dibandingkan dengan pemasaran secara offline. Terlebih lagi di situasi COVID-19 yang sedang melanda dunia tak terkecuali Indonesia, pemasaran online dianggap sebagai salah satu cara bagi para pelaku usaha agar dapat mempertahankan usaha ataupun jasa yang mereka pasarkan. Namun pada situasi saat ini, pemasaran online berdampak terhadap beberapa sektor yang dialami oleh para pelaku usaha.Keyword: Pemasaran Online, COVID-19.
THE IMPACT OF WORK DISCIPLINE, WORK ENVIRONMENT ON EMPLOYEE PERFORMANCE IN MARINE AND FISHERY SERVICES SOUTH ACEH DISTRICT
Authors: Bahri Saipul 
Published: November 2022

This study aims to see the effect of work discipline and work environment on employee performance at the Department of Maritime Affairs and Fisheries, South Aceh Regency. This research is quantitative descriptive. The research population is all civil servants and non-civil servants who work in the service, totaling 50 people. Questionnaires were distributed to all respondents with 33 respondents who returned the questionnaire which were then used as research samples. The results showed that partially work discipline had a positive and significant effect on employee performance. The work environment has a positive but not significant effect on employee performance at the Department of Marine Affairs and Fisheries, South Aceh Regency. Simultaneously, the variables of work discipline and work environment have a positive and significant influence on the performance of employees at the Department of Maritime Affairs and Fisheries, South Aceh Regency. Overall, work discipline and work environment variables can only explain employee performance variables as much as 33%, while 77% percent are explained by other factors not mentioned in the study. Keywords: Work Discipline, Employee Performance, Work Environment, Motivation.
ANALISIS PERUBAHAN DANA PERIMBANGAN DAN PENDAPATAN ASLI DAERAH TERHADAP KINERJA KEUANGAN PEMERINTAH DAERAH PROVINSI RIAU
Authors: Seswandi Agus , Arini Arini , Novianti Serly 
Published: November 2022

Penelitian ini adalah untuk mengetahui dan menganalisis perubahan Dana Perimbangan dan Pendapatan Asli Daerah terhadap Kinerja Keuangan Pemerintah Daerah Provinsi Riau. Metoda Analisis dalam penelitian ini menggunakan analisis regresi berganda (Multiple Regression). Untuk mengetahui pengaruh perubahan dana perimbangan dan PAD dengan tingkat kinerja pemerintah daerah maka dilakukan pengujian pengujian hipotesis penelitian terhadap variabel-variabel dengan uji F dan Uji t dan koefisien Determinasi. Dari hasil penelitian diperoleh kesimpulan bahwa terdapat pengaruh signifikan secara simultan antara Variabel Pendapatan Asli Daerah dan Dana Perimbangan terhadap Kinerja Keuangan Daerah Provinsi Riau. Sementara secara parsial hanya Pendapatan Asli Daerah yang berpengaruh signifikan terhadap Kinerja Keuangan Daerah, sedangkan Variabel Dana perimbangan tidak signifikan pengaruhnya terhadap Kinerja keuangan Daerah Riau
Modernisasi Industri Gitar di Kecamatan Baki Kabupaten Sukoharjo Provinsi Jawa Tengah
Authors: Verinza Afif Baihaqi , Ningrum Sylvia Mildiana , Atmaja Lilis Karunia , Riswan Fajri Irfani , Silvia Misya , Hafida Siti Hadiyati Nur 
Published: November 2022

The guitar industry in Baki District is the center of guitar manufacture in Sukoharjo Regency. To maintain its existence in the community, this industry requires a modern digital-based production, sales and marketing system. This study aims to analyze the extent of modernization carried out by the guitar industry in relation to the production, sales, and marketing of products. This research uses descriptive quantitative research. The selection of respondents was carried out by purposive sampling and obtained as many results 32 sample,while the analysis technique used was descriptive statistics. The results of the analysis show that the guitar industry has not been maximized in utilizing the existing of modernization. This is indicated by the strength factor in the form of human resources, while the weakness is in the form of open market share. Therefore, with the strengths and weaknesses it has, it is found that there are a problems that make guitar product sales have not reached the maximum point, that is modernization in production, marketing, and sales. AbstrakIndustri gitar di Kecamatan Baki merupakan sentra pembuatan gitar di Kabupaten Sukoharjo.Untuk mempertahankan eksistensinya di kalangan masyarakat, industri ini memerlukan sistem produksi, penjualan, dan pemasaran yang modern berbasis digital. Penelitian ini bertujuan untuk menganalisis sejauh mana modernisasi yang dilakukan oleh pelaku industry gitar dalam kaitannya dengan produksi, penjualan, dan pemasaran produk.Penelitian ini menggunakan jenis penelitian kuantitatif deskriptif.Pemilihan responden dilakukan secara purposive sampling dan diperoleh hasil sebanyak 32 sampel, sedangkan teknik analisis yang digunakan adalah statistik deskriptif.Hasil analisis menunjukkan bahwa industri gitar belum maksimal dalam memanfaatkan modernisasi yang ada. Hal tersebut ditunjukkan dengan adanya factor kekuatan berupa sumber daya manusia sedangkan kelemahannya berupa terbukanya pangsa pasar oleh karena itu, dengan kekuatan dan kelemahan yang dimilikinya tersebut, ditemukan permasalahan yang membuat penjualan produk gitar belum mencapai titik maksimal, yaitu modernisasi dalam produksi, pemasaran, dan penjualan.
Efektivitas Pembelajaran E-Learning Menggunakan Aplikasi Google Classroom Terhadap Hasil Belajar Geografi Peserta Didik Kelas X SMA Negeri 14 Makassar
Authors: Hasriyanti Hasriyanti , Arfan Amal , Faisal Siti Raihanah Rinduputri 
Published: November 2022

This study aims to determine the effectiveness of using the Google Classroom application in learning geography for class X students of SMA Negeri 14 Makassar referring to learning outcomes. This is a pre-experimental study involving one experimental group, namely class X MIPA 5 using purposive sampling technique. Data collection was carried out using learning outcomes tests and questionnaires. The data analysis technique used is statistical analysis technique and product moment correlation. The results of the study stated that the use of Google Classroom on the geography learning outcomes of class X students of SMA Negeri 14 Makassar was not effective. The relationship between the two variables was tested for significant correlation coefficient with t test obtained tcount (2,386) > ttable (2,045), so that H0 was accepted with a contribution of 16.4025%. There are inhibiting factors, namely: constrained internet access and supporting factors, namely the application of Google Classroom and student motivation. AbstrakPenelitian ini bertujuan mengetahui efektivitas penggunaan aplikasi Google Classroom dalam pembelajaran goegrafi di kelas X SMA Negeri 14 Makassar mengacu pada hasil belajar. Merupakan penelitian pre eksperimen yang melibatkan satu kelompok ekperimen yaitu kelas X MIPA 5 menggunakan teknik purposive sampling. Pengambilan data dilakukan dengan menggunakan tes hasil belajar dan angket. Teknik analisis data yang digunakan adalah teknik analis statistika dan korelasi product moment. Hasil penelitian menyatakan bahwa penggunaan Google Classroom terhadap hasil belajar geografi siswa kelas X SMA Negeri 14 Makassar tegolong tidak efektif. Hubungan antara kedua variabel dilakukan pengujian signifikan koefisien korelasi dengan uji t diperoleh thitung (2,386) > ttabel (2,045), sehingga H0 diterima dengan kontribusi sebesar 16,4025%. Terdapat faktor penghambat yaitu: terkendala akses internet serta faktor pendukung yaitu pengaplikasian Google Classroom dan motivasi siswa.
Potensi Air Tanah Sebagai Sumber Air Baku Masyarakat di Desa Holimombo Kecamatan Wabula Kabupaten Buton
Authors: Iskandar Ahmad , Kamur Sudarwin , Nasarudin Nasarudin , Yulianto Andri 
Published: November 2022

Holimombo Village is an area with a karst landscape, where the problems in the area are the absence of surface water sources. Based on these problems, the research objective is to identify the potential of groundwater as a source of raw water for the community in Holimombo Village, Wabula District, Buton Regency. The research is a quantitative descriptive study, where the subsurface resistivity data was used. The Field observation techniques were used for data collecting in this study, where the measurement of the subsurface resistivity value uses a set of geoelectrical resistivity meters. The results of the geoelectric measurements will then be processed using the Res2DinV application. The subsurface resistivity measurements were carried out in four different paths. Based on the measurement results, the subsurface resistivity values at the research site in Holimombo Village, Wabula District, Buton Regency vary, ranging from 6.64 Ωm to above 1000 Ωm. Areas that have ground water potential are on the line 4 with coordinates 5°33,751' S and 122°53,112' E. The layer at this point is weathered limestone in the form of sand and gravel which has groundwater potential because it has a resistivity value of 50-500 Ωm. The potential for groundwater at that point is quite a lot with a thickness of 27.7 m. Therefore, this potential can be utilized by the Holimombo Village community as a source of daily raw water. AbstrakDesa Holimombo merupakan daerah dengan bentang alam kars, dimana permasalahan di daerah tersebut adalah tidak adanya sumber air permukaan. Berdasarkan permasalahan tersebut, maka tujuan penelitian ini adalah untuk mengidentifikasi potensi air tanah sebagai sumber air baku masyarakat di Desa Holimombo, Kecamatan Wabula, Kabupaten Buton. Penelitian ini merupakan penelitian deskriptif kuantitatif, dimana data yang digunakan berupa nilai resistivitas bawah permukaan. Teknik observasi lapang digunakan untuk pengumpulan data dalam penelitian ini, dimana pengukuran nilai resistivitas bawah permukaan menggunakan satu set alat geolistrik resistivitymeter. Hasil pengukuran geolistrik tersebut selanjutnya akan diolah dengan menggunakan aplikasi Res2DinV. Pengukuran resistivitas bawah permukaan dilakukan di empat lintasan berbeda. Berdasarkan hasil pengukuran diperoleh nilai resistivitas bawah permukaan di lokasi penelitian di Desa Holimombo Kecamatan Wabula Kabupaten Buton bervariasi, mulai dari 6,64 Ωm sampai dengan di atas 1000 Ωm. Wilayah yang memiliki potensi air bawah tanah yaitu pada lintasan 4 pada titik koordinat 5°33.751' LS dan 122°53.112' BT. Lapisan di titik ini merupakan lapukan batu gamping yang berupa pasir dan kerikil yang memiliki potensi air tanah karena memiliki nilai resistivitas 50-500 Ωm. Potensi air tanah di titik tersebut cukup banyak dengan ketebalan 27,7 m. Oleh sebab itu, potensi ini dapat dimanfaatkan oleh masyarakat Desa Holimombo sebagai sumber air baku sehari-hari.
Strategi Pengembangan Objek Wisata Appa’ di Pulau Kayuadi Kabupaten Kepulauan Selayar Sulawesi
Authors: Invanni Ichsan , Maru Rosmini , Reskianti Reskianti 
Published: November 2022

Appa' tourism is one of the icons owned by the people of the Selayar Islands Regency. Seeing the development of the times, the flow of tourism must also be addressed and developed, including the appa' tourist attraction. This Study aims to find out (1) Reveal the characteristics of the Appa’ tourist attraction on Kayuadi Island, Selayar Islands Regency (2) Formulate a strategy for developing Appa’ tourism object on Kayuadi Island, Selayar Island Regency. This research method is descriptive qualitative method. Descriptive qualitative research is research that aim to describe and describe events,and events that occur in the field that present factual, systematic and accurate data that does occur according to field facts. Data collection techniques in this study were observation, interviews, and documentation. The data analysis technique used in this research is descriptive analysis and SWOT analysis. AbstrakPariwisata appa’ merupakan salah satu ikon yang dimiliki oleh masyarakat Kabupaten Kepulauan Selayar. Melihat prkembangan zaman, arus pariwisata juga mesti di benahi dan dikembangkan, tak terkecuali objek wisata appa’. Penelitian ini bertujuan untuk mengetahui (1) Mengungkapkan karaketristik objek wisata Appa’ di Pulau Kayuadi Kabupaten Kepulauan Selayar (2) Merumuskan strategi pengembangan objek wisata Appa’ di Pulau Kayuadi Kabupaten Kepulauan Selayar. Metode penelitian ini adalah metode kualitatif deskriptif. Penelitian kualitatif deskriptif adalah penelitian yang bertujuan untuk mendeskripsikan dan menggambarkan kejadian maupun persitiwa yang terjadi di lapangan yang memaparkan data secara faktual, sistematis serta akurat yang memang terjadi sesuai fakta dilapangan. Teknik pengumpulan data pada penelitian ini adalah observasi, wawancara, dan dokumentasi. Teknik analisis data yang digunakan dalam penelitian ini adalah Analisis Deskriptif dan Analisis SWOT.
Observasi SAR untuk Perubahan Lahan Pasca Gempa 7,5 Mw NTT di Pulau Selayar
Authors: Yanti Jeddah 
Published: November 2022

An earthquake with a magnitude of 7.5 occurred on December 14, 2021, with an epicenter location at 112-kilometers northwest of Larantuka, NTT, causing an impact on the Selayar Islands. Damage to structures, infrastructure, and changes in the ground surface structure occurred in most of Selayar Island. Changes in the structure of the ground surface that occurred were identified by utilizing SAR satellite imagery of Sentinel-1 A and Sentinel-1 B in the post-event time range, namely December 05 to December 11, 2021, the event which was December 11 to December 17, 2021, and post-event, namely December 17, 2021, to January 04, 2022. The DInSAR method is used to identify the value of the phase difference and the direction of earthquake wave energy. The results of the DInSAR approach obtained a change in the value of the phase difference of more than 3 cm at the post-event, event, and post-event. The distribution of phase difference values shows an adverse change in vertical deformation in the event category between December 11, 2021, to December 17, 2021. More than 50 percent of the distribution of phase difference values shows land subsidence. The result shows that earthquakes can trigger land surface change on Selayar Island. AbstrakGempa berkekuatan 7,5 magnitudo terjadi pada 14 Desember 2021 dengan lokasi epicentrum di 112-kilometer barat laut Larantuka, NTT menimbulkan dampak hingga Kepulauan Selayar. Kerusakan struktur, infrastruktur serta perubahan struktur permukaan tanah terjadi di sebagian besar Pulau Selayar. Perubahan struktur permukaan tanah yang terjadi di Pulau Selayar diidentifikasi dengan memanfaatkan citra satelit SAR Sentinel-1 A dan Sentinel-1 B pada rentang waktu post-event yakni 05 Desember 2021 hingga 11 Desember 2021, event yakni 11 Desember 2021 hingga 17 Desember 2021, dan pasca event yakni 17 Desember 2021 hingga 04 Januari 2022. Metode DInSAR digunakan untuk mengidentifikasi nilai beda fase dan arah perambatan energi gelombang gempa bumi. Hasil pendekatan DInSAR didapatkan perubahan nilai beda fase lebih dari 3 cm pada post-event, event dan pasca event. Sebaran nilai beda fase menunjukkan perubahan negatif pada vertical deformation di kategori event di antara rentang waktu 11 desember 2021 hingga 17 desember 2021. Dengan lebih dari 50 persen sebaran nilai beda fase menunjukkan penurunan permukaan tanah. Hal ini menunjukkan bahwa gempa bumi merupakan salah satu faktor yang dapat memicu terjadinya perubahan permukaan tanah yang terjadi di Pulau Selayar.