bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autoimmune thyroiditis in different age groups and subjects of reproductive age in Adzhariya population
Authors: Tchelidze N. G. , Glonti S. Z. , Baratashvili D. Sh. , Kedelidze N. O. , Ungiadze J. Yu. , Nakashidze I. I. 
Published: March 2022

Introduction. Autoimmune thyroiditis (AIT) is the most prevalent among the autoimmune pathologies and multifactorial thyroid diseases; accordingly, remaining a pressing issue for investigation.Aim: to study AIT profile in different age groups of the female population in the western region of Georgia – Adzhariya.Materials and Methods. A prospective comparative study in parallel groups was carried out. There were examined 405 samples of venous blood obtained at «Health» Clinic from women of two groups: group 1 – 159 patients with AIT, group 2 (control) – 246 women without AIT. Blood samples were collected between the years 2017 and 2020. There were analyzed serum antibodies against thyroperoxidase (TPOAb), thyroid stimulating hormone (TSH) as well as level of free thyroxine (FT4) by using enzyme immunoassay.Results. Patients with AIT from different age groups vs. control group were found to have decreased level of FT4, but increased amount of TSH and TPOAb. At the reproductive age (18–45 years), a significant increase in the level of TSH was found (6.12 times) compared with the control group (p < 0.0001). The level of FT4 and TSH in AIT women aged 51 to 60 years was 0.7880 ± 0.3584 ng/ml and 4.754 ± 2.433 U/ml that significantly differed from those in the control group – 1.314 ± 0.4044 ng/ml (p < 0.0001) and 2.276 ± 1.409 U/ml (p < 0.0001), respectively.Conclusion. AIT occurs in women of all age groups, but is more common in women aged 51 to 60 years. In a number of cases, TPOAb was detected in the control group, which, apparently, is associated with increased intake of dietary iodized salt since 2005 in Georgia (the adoption of the law on universal salt iodization). A significant increase in the level of TSH, in AIT women aged 18–45 years, strongly suggests to perform diagnostics of and screening for AIT not only in females of menopausal period, but also in reproductive age.
Optimization of 17α-Methyl Testosterone Dose in Artemia Nauplii and Rotifer using Enrichment Technique
Authors: Bhosle R.V. , Kumar J.S. Sampath , Antony Cheryl , Aanand S. , Senthilkumar V. , Lingam R.S.S. 
Published: March 2022

Background: The present study explored the possibility of using live feed, as vector for supplementing the androgenic hormone in aquaculture seed production. Methods: The study consisted of five treatment doses of 17α-methyl testosterone namely; control (without hormone), T1 (20 mg L-1), T2 (40 mg L-1), T3 (60 mg L-1) and T4 (80 mg L-1) and each were triplicated. The doses were tested in the live feed of Artemia nauplii and rotifer by following completely randomized design. The Artemia nauplii (Artemia salina), collected by hatching the Artemia cyst and 5-8 days old rotifers, collected from mass culture unit of rotifer, were released in their respective treatment doses at 100 and 800 individuals/ml, respectively. Result: The study found significant difference in accumulation of hormone in the tissues of live feed at different time intervals. In Artemia, significantly higher amount of 17α-MT (15.33±0.09 mg L-1) was observed in 80 mg L-1 group at 24 h. In rotifer, significantly higher value of 17α-MT (17.42±0.06 mg L-1) was recorded in 60 mg L-1 group at 6 h. The level of 17α-MT in Artemia nauplii and rotifer started showing a decreasing trend in 24 h and 6 h, respectively. Overall the findings of the present study support that supplementation of hormone through live feed is possible as live feed accumulated 17α-MT in its tissue after enrichment which can be further explored for producing all-male population in a more sustainable way.
Temperature-based Climate Projections of Pinot noir Suitability in the Willamette Valley American Viticultural Area
Authors: Skahill Brian , Berenguer Bryan , Stoll Manfred 
Published: March 2022

In this study, we consider the complete archive of the 32 Coupled Model Intercomparison Project Phase 5 (CMIP5) daily Localized Constructed Analogs (LOCA) downscaled historic datasets and their observational data that were used for downscaling and bias corrections to develop an ensemble that optimises calculation of the growing season average temperature (GST) viticulture climate classification index throughout the Willamette Valley (WV) American Viticultural Area (AVA). Ensemble directed spatiotemporal calculations, using LOCA CMIP5 historic and RCP4.5 future datasets of minimum and maximum daily temperature, were performed throughout the WV AVA for the GST index and Pinot noir specific applications of the grapevine sugar ripeness (GSR) model at a 220 g/L target sugar concentration. The GST index and GSR model evaluations were calculated on a mean decadal basis from the 1950s to the 2090s for the WV AVA. The GST index and GSR model calculations both revealed a warming trend with time for the WV AVA. A 3.1 °C increase in the GST index is predicted from the 1950s to the 2090s. The GSR model indicated a rate advance of 2.9 days a decade from the 1960s to the 2080s. However, the application of the GST index and the GSR model portray markedly different characterisations about the suitability of Pinot noir throughout the WV AVA with time. A strong invertible relationship between the GST index and GSR model calculations is observed and exploited to update the Pinot noir specific lower and upper bounds (14.8 °C, 17.6 °C) for the GST index throughout the WV AVA. Pinot noir specific applications of the GSR model or the GST index with updated bounds indicate that the percent of the WV AVA area suitable for Pinot noir production is currently at or near its peak value in the upper 80s to the lower 90s.
O aparente controle social no âmbito da Administração Pública brasileira
Authors: Santos Pereira Guedes Luciana Kellen , Ferreira de Faria Edimur 
Published: March 2022

Com esta pesquisa objetiva-se mostrar a inexistência de um controle social efetivo no Brasil e revelar que o controle social instituído no ordenamento jurídico brasileiro a partir da Constituição de 1988 é apenas aparente, em face da ausência de instrumentos necessários ou de estímulo à democracia participativa. Inicia-se com uma noção histórica do controle social e a implementação da democracia participativa na Constituição de 1988. Aponta-se o papel do controle social e analisam-se os institutos jurídicos à disposição da sociedade para fiscalizar as atividades dos entes estatais. Segue-se mostrando que, na verdade, esses institutos normativos dão apenas uma “aparência” de direito ao exercício do controle social. Identificam-se a ausência de instrumentos de fomento e de facilitação do controle social e a inexistência de proteção à população como fenômenos que obstacularizam o exercício de controle social efetivo. Esses mecanismos são necessários e inerentes ao controle social, sem os quais tornam sem força os enunciados que deles emanam. Ao final, defende-se a atuação efetiva do Estado na emissão de leis e atos infralegais, seja para a concretização de enunciados normativos existentes, seja para a introdução, no sistema jurídico brasileiro, de mecanismos novos de fortalecimento do controle social. O método de trabalho é o hipotético-dedutivo, e as investigações jurídico-interpretativa e jurídico-comparativa realizadas são eminentemente teóricas. O estudo teórico realizado está amparado por pesquisa bibliográfica, documental e visita a sítios institucionais, tendo como referencial teórico o filósofo Jacques Derrida, responsável pela introdução do estilo desconstrutivista. Os resultados apontam que o controle social do ordenamento jurídico brasileiro retrata uma democracia participativa aparente, voltada para atender aos interesses dos poderes político e econômico dominantes.
Analysis of the Association of 5-Hydroxytryptamine Receptor 2A Gene Variants in Nicotine Addiction in the Yakut Population
Authors: Pavlova Nadezhda , Bochurov Aleksey , Alekseev Vladislav , Diakonova Aleksandra , Dodokhov Vladimir , Kurtanov Khariton 
Published: March 2022

The aim of this study was to investigate the relationship between the HTR2A 1438A/G (rs6311) SNP and the risk of nicotine addiction in Yakuts.	Methods and Results: A total of 292 people of Yakut nationality were tested (77 women and 215 men). Two groups of examined persons were formed: smokers (n=141) and non-smokers (NS, n=151). To determine the association of the studied SNP with the degree of smoking, the smoker group was divided into two subgroups: Heavy smokers (HS) and Light smokers (LS). Subjects who were smokers were classified based on their consumption of cigarettes per day (cpd), as follows: LS (n=10), those who consumed between 1 and 10 cpd, and HS (n=131), those who consumed ≥20 cpd. The study of the HTR2A 1438A/G (rs6311) SNP was performed by PCR and RFLP analysis. The A allele of the HTR2A 1438A/G (rs6311) SNP was associated with more of a risk for the HS group than the LS. Using the A allele as a risk factor, RR analysis showed a significant association with a risk factor when comparing HS with LS (RR=1.086; 95% CI=1.032-1.142; P=0.049). The analysis of the OR and RR between the HS and LS showed that the AA and AG genotypes were associated with an increased risk for heavy smoking (OR=9.714; 95% CI=1.196-78.874; RR =1.126; 95% CI=1.027-1.235; P=0.026). We cannot dismiss the possibility that our results may reflect the small sample size. Despite this potential limitation, the significant associations should not be disregarded and merit further investigation for clarification of these results.
Leukocyte Shift Index and Subtypes of Acute Otitis Media in Children
Authors: Kuznetsova Nadezhda , Ponomareva Maria , Kuznetsova Tatiana 
Published: March 2022

The aim of this research was to study the features of clinical and laboratory parameters of acute otitis media (AOM), taking into account the value of the leukocyte shift index (LSI) in pediatric patients with the demonstration of clinical cases. Methods and Results: This study included 100 children (55 boys and 45 girls) with AOM. The mean age of all patients was 4.32±0.31 years. Group 1 included 50 patients (30 boys and 20 girls) with acute suppurative otitis media (SupAOM) . Group 2 included 50 patients (25 boys and 25 girls)with acute serous otitis media (SerAOM). As a marker for determining the activity of the inflammatory process and the disorders of the immunological reactivity of the body, we chose LSI, calculated taking into account the parameters of the general blood test.	Our results show the diagnostic significance of LSI in predicting the clinical course of AOM in patients in the age group of 2-16 years. The development of SerAOM is predicted when the LSI is 1.05±0.08; SupAOM - 2.08±0.23 The results obtained can be useful in providing specialized medical care for children of this age group, for optimizing the algorithms for preventive examinations and therapeutic interventions, and for offering the possibility of predicting the severity of the disease and timely treatment of SupAOM requiring a surgical intervention followed by systemic antibiotic therapy in order to prevent otogenic complications and hearing.
Providing the necessary type of metal microstructure of titanium and zirconium pipes.
Authors: Tomilo V. A. , Pilipenko S. V. 
Published: March 2022

The purpose of this work is – providing deformation conditions for obtaining the required texture of pipes made of Ti-3Al-2.5V alloy based on the choice of rational values of the calibration parameters of the t ool – calibers and mandrels during cold pilger rolling of pipes for the required Q-factor distribution along the deformation cone.Purpose of work – providing deformation conditions for obtaining the required texture of pipes made of Ti-3Al-2.5V alloy based on the choice of rational values of the calibration parameters of the tool – calibers and mandrels during cold pilger rolling of pipes for the required Q-factor distribution along the deformation cone. The research methods were based on the existing dependence, which describes the influence of the distribution of true compressions along the deformation cone along the wall thickness and along the average diameter, on the distribution of the Q-factor. Calibration calculation and calculation of all deformation parameters of the Cold Rolling Pipe Process was based on a number of existing theoretical and empirical dependencies included in the generally accepted adapted methods for their calculation.
Requirements for the mass and heating of blanks selection in automated ring-rolling complexes
Authors: Antonyuk V. E. , Sandomirski S. G. , Yavorsky V. V. , Timoshenko N. P. , Budzinskaya A. V. 
Published: March 2022

The conditions for choosing a billet mass for the manufacture of an ring part on an automated ring-rolling complex, the features of heating the billets in the conditions of an automated line and heat treatment of manufactured parts are considered. The expediency of differentiated assignment of tolerances for the rings’ sizes after ring rolling, depending on their type, conditions of subsequent mechanical treatment and operation, is substantiated. Attention is focused on the need to design a ring-rolling technology with control of the billet parameters not only during the cutting, heating and pressing operations, but also before the ring-rolling operation, especially when using reheating. To evaluate the technological temperature state of the ring blanks at different stages of manufacturing in an automated line, it is offered to use the billet’s “conventional temperature”, which is determined in the 2nd zone from the middle of the billet. The use of single gas heating of billets in rotary-hearth furnaces in the manufacture of annular billet on an automated line is justified. The problems of the automated ring rolling line and the heat treatment complex synchronization are determined. It is shown that the clock capacity of the automated ring rolling line significantly exceeds the clock capacity of the planned heat treatment complex. It is concluded that it is necessary to develop software for their synchronous operation.The proposed recommendations are intended for the development of technological support for an automated ring-rolling complex at OJSC “PAK Plant” as part of “BELAZ-HOLDING”.
Determination of the optimal horizontal boring mill for the repair of the pipe-rolling reduction-stretching mill’s body stands
Authors: Filonchik O. N. 
Published: March 2022

The article defines the optimal equipment necessary for the repair of the body stands of a pipe-rolling reduction-stretching mill. The body stand of the mill crate, made of 40X structural alloy steel, undergoes wear of the bearing seats during operation. Body stands restoration is carried out by surfacing the worn surfaces of the part with subsequent machining to the dimensions specified in the design documentation. In the process of surfacing medium-carbon steels, carbides are formed, which leads to a sharp increase in hardness in the zone of thermal influence, which affects the durability of carbide plates and processing accuracy.It is necessary to consider the geometric shape, dimensions, weight and material of the part while choosing equipment for repairing the body stand. Using a horizontal boring machine with a horizontal spindle performing rotational and translational movement of the axial feed, it is necessary to take into account the rigidity of the spindle, which affects the accuracy of processing, especially when restoring deep holes after surfacing with hardening surfacing materials. Bending the spindle can cause vibration and beating, which will affect the quality of the work performed. An increase in the rigidity of the machining can be achieved by using a drilling rod or by increasing the diameter of the spindle. Since it is necessary to restore deep blind holes in the repaired housing, it is impossible to use a drilling rod. In the process of work, the optimal diameter of the spindle of the horizontal boring machine was determined, taking into account the design features of the work piece.
Discharge coefficients for ogee spillways
Authors: Salmasi Farzin , Abraham John 
Published: March 2022

Abstract
Discharge over an ogee weir is related to the length of the weir, upstream total head above the weir crest and the discharge coefficient. The discharge coefficient is influenced by several factors; in this study, some parameters that influence discharge coefficients of ogee weirs are investigated. These factors include: the weir upstream slope, apron elevation, and downstream submergence. In this regard, ogee weir physical models were fabricated. These models comprise: an ogee weir with a vertical upstream face, ogee weirs with inclined upstream faces (18, 33, and 45 degrees), ogee weirs with downstream apron thicknesses of 3, 5, 7, and 10 cm in free flow and an ogee weir with a vertical upstream slope under submerged-flow conditions. Results show that for all ogee weirs, the discharge coefficient (C) increases with increasing P/He, and then remains constant (P is the spillway height and He is the head above the weir crest). The value of the discharge coefficient decreases from 2.25 in free-flow conditions to 2.15 with submerged-flow conditions. For a constant head over the ogee weirs (He), the discharge coefficient decreases with increasing downstream apron elevation and submergence. The relative discharge coefficient shows a constant trend initially, with increasing hd/He, then later shows a decreasing tendency (hd is the difference between the downstream head and the ogee spillway crest). The threshold value for submergence ratio (hd/He) is 0.75 in the ogee weir in this study. With increasing submergence ratio from 0.75 to 1, the relative discharge coefficient (Cs/C0) decreases from 0.88 to 0.24.
Pendidikan berbasis nilai untuk guru taman kanak-kanak
Authors: Rukiyati Rukiyati , Purwastuti Lusila Andriani , Hajaroh Mami , Rohman Arif 
Published: March 2022

Studi ini bertujuan untuk meningkatkan kemampuan profesional guru dalam menghidupkan nilai-nilai yang diterapkan di sekolah. Kegiatan ini menggunakan strategi berupa teori, dialog, dan proyek. Instrumen yang digunakan adalah kuis dan angket. Teknik analisis menggunakan analisis deskriptif. Subjek kegiatan adalah guru Taman Kanak-Kanak di berbagai wilayah di Indonesia, meliputi Nusa Tenggara Timur, Sumatera, Jawa dan Hong Kong sejumlah 142 orang. Hasil kegiatan menyimpulkan bahwa para guru telah dapat memahami nilai-nilai dan mempraktikkannya di dalam kegiatan pembelajaran. Para peserta mengungkapkan bahwa mereka mendapatkan ilmu yang sangat bermanfaat dan juga dapat bertukar pengalaman dengan guru di luar Yogyakarta sehingga pertemanan peserta tampak semakin akrab. Peserta menilai kegiatan telah berjalan sangat baik dan bermanfaat. Saran dalam kegiatan selanjutnya adalah dilibatkannya orang tua siswa dalam kegiatan ini sehingga tujuan pendidikan berbasis nilai dapat dicapai dengan lebih optimal.Kata kunci: Pendidikan taman kanak-kanak, nilai-nilai, kompetensi guru
High order thinking skill sebagai landasan dalam pengembangan asesmen dan evaluasi pendidikan
Authors: Hajaroh Mami 
Published: March 2022

Studi ini memberikan wawasan tentang konsep high order thinking skill sebagai kompetensi yang integral dengan low order thinking skill. Kompetensi berpikir kritis dan kreatif sebagai kompetensi level tinggi terbentuk dari kompetensi berpikir level rendah dari kemampuan mengingat, memahami, menerapkan, berpikir analitis, berpikir kritis dan berpikir kreatif. Pengetahuan sebagai obyek berpikir memiliki dimensi-dimensi dari pengetahuan faktual, konseptual, prosedural dan pengetahuan metakognitif. Pendidik dalam proses pembelajaran membantu peserta didik berproses untuk mencapai kompetensi berpikir tingkat tinggi melalui pembelajaran pengetahuan yang multi dimensi tersebut dan melakukan asesmen kelas untuk membantu proses pencapaian kompetensi serta memastikan ketercapaian kompetensi melalui evaluasi hasil belajar. Taksonomi pendidikan yang ditemukan oleh Bloom merupakan konsep dasar yang selalu menjadi rujukan dalam menyusun tujuan atau kompetensi pendidikan dan evaluasinya. Kompetensi berpikir kreatif sebagai kompetensi berpikir tingkat tinggi ditambahkan oleh Andersen di tahun 2001. Pembaruan taksonomi Bloom yang dilakukan oleh Andersen menjadikan konsep ini relevan dengan konteks dunia di abad 21.
APLIKASI TEORI BELAJAR KONSTRUKTIVISME DALAM PEMBELAJARAN BAHASA ASING
Authors: Ningsih Ningsih 
Published: March 2022

Sebagai sarana komunikasi, bahasa memegang peranan penting dalam kehidupan juga dalam kelas. Namun dalam kegiatan kelas, siswa sering merasa sulit untuk memahami teks, karena topik baru yang dibawa oleh guru tidak memiliki keterkaitan dengan pengetahuan mereka sebelumnya. Konstruktivisme adalah pendekatan yang menunjukkan bahwa pembelajaran lebih efektif dan bermakna ketika siswa mampu berinteraksi dengan masalah atau konsep. Contoh pembelajaran dengan menggunakan prinsip teori belajar konstruktivisme adalah gagasan pembelajaran bahasa kolaboratif, pembelajaran berbasis proyek, pembelajaran berbasis tugas dan permainan peran. Kata Kunci: Konstruktivisme, Teori belajar, Bahasa asing
PENANAMAN NILAI-NILAI NASIONALISME MELALUI KEARIFAN LOKAL PARA BURUH MIGRAN DI HONG KONG
Authors: Rukiyati Rukiyati , Hajaroh Mami , Purwastuti Lusila Andriani 
Published: March 2022

Para buruh migran yang bekerja di Hong Kong perlu diberi motivasi dan wawasan keindonesiaan dan rasa nasionalisme agar mereka bekerja dengan tekun tetapi mempunyai target yang jelas untuk kembali ke tanah air. Pemberian motivasi dan wawasan dilakukan dengan media kearifan lokal Indonesia berupa pengenalan kembali dan menyanyikan lagu-lagu tradisional, dan lagu wajib serta memasak makanan tradisional Indonesia. Peserta pelatihan ini adalah para buruh migran yang tergabung dalam organisasi nirlaba TCKLC Hong Kong sebanyak 25 orang, kesemuanya perempuan. Metode PPM yang digunakan adalah ceramah singkat, diskusi, penugasan, praktik, dan bernyanyi. Hasil kegiatan PPM menunjukkan para buruh migran sangat senang menerima pelatihan penanaman nilai-nilai nasionalisme melalui kearifan lokal. Diperoleh kesadaran dari para buruh migran bahwa walaupun di Hong Kong mereka mendapatkan penghasilan yang cukup besar, tetapi tetap merasa sebagai kurang bermartabat, kurang terhormat. Setelah pelatihan,para buruh migran merasa sangat termotivasi untuk pulang ke tanah air dengan rencana yang jelas untuk pekerjaan dan kegiatannya masing-masing. Bekal dari Hong Kong berupa uang akan dimanfaatkan untuk usaha dan sekolah, sedangkan bekal ilmu akan digunakan untuk bekerja menjadi guru di daerahnya masing-masing. Lima bulan setelah pelatihan, diperoleh informasi sebagian buruh migran yang telah selesai masa kontraknya benar-benar telah kembali ke tanah air dan bekerja sesuai rencana ketika pelatihan. Ada yang menjadi guru PAUD, guru bahasa Inggris, melanjutkan pendidikan, dan ada pula yang berwirausaha. Kata kunci: Nilai nasionalisme, buruh migran, kearifan lokal