bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Reductive Benzylation for Benzenes Using Aroyl Chlorides and Triethylsilane Catalyzed by Aluminosilicate-Stabilized Silyl Cations on Montmorillonite
Authors: Onaka Makoto , Tanaka Yoshiki , Shibata Shintaro , Hashimoto Kimiko , Masui Yoichi 
Published: August 2022

AbstractWe discovered that the aluminosilicate-stabilized silyl cations, which were created from a solid-acid catalyst, the proton-exchanged montmorillonite, and Et3SiH, efficiently promoted the reductive benzylation of benzenes with aromatic carboxylic acid chlorides and Et3SiH in one pot.
End-of-Treatment FDG PET-CT (EOT-PET) in Patients with Post-Chemotherapy Masses for Seminoma: Can We Avoid Further Intervention?
Authors: Joel Anjana , Singh Ashish , Hepzibah Julie , Devasia Antony , Kumar Santosh , Gnanamuthu Birla Roy , Chandramohan Anuradha , George Arun Jacob Philip , John Nirmal Thampi , Yadav Bijesh , John Ajoy Oommen , Georgy Josh Thomas , John Subhashini , Chacko Raju Titus 
Published: August 2022

Context Patients with seminoma present with advanced disease. End-of-treatment (EOT) positron emission tomography-computed tomography (PET-CT) is done to assess response and direct management of post-chemotherapy residual masses.
Purpose This article assesses the utility of EOT PET-CT in the management of post-chemotherapy residual lymph nodal masses seminoma.
Materials and Methods We analyzed all patients with seminoma who underwent an EOT PET-CT from January 2015 to January 2020 at our center and calculated the positive predictive value (PPV) and negative predictive value (NPV) of EOT PET-CT in the entire cohort of patients and among subgroups.
Results A total of 34 male patients underwent EOT PET-CT. Fourteen (41.2%) were stratified as good risk and 20 (58.8%) as intermediate risk. The median follow-up was 23 months (interquartile range: 9.75–53 months). In 23 patients there were residual masses of size more than 3 cm at the EOT PET scan. EOT PET was positive as per the SEMPET criteria in 18 (78%) out of 23 patients. None underwent retroperitoneal lymph node dissection. All four who underwent image-guided biopsy, showed only necrosis on pathology. One patient with positive mediastinal node (standardized uptake value 13.6) had granulomatous inflammation. There was no relapse or progression during this period of follow-up. The NPV for EOT PET-CT for the entire cohort, > 3 cm, and > 6 weeks cutoff were 100%, respectively. The PPV for EOT PET-CT for the entire cohort, > 3 cm residual mass, and > 6 weeks cutoff were 8.7, 11.11, and 6.67%, respectively.
Conclusion EOT PET-CT has a low PPV and high NPV in predicting viable tumor in post-chemotherapy residual masses among patients with seminomatous germ cell tumors. If required, EOT PET positivity can be confirmed by a biopsy or reassessed with a repeat PET-CT imaging to document persistent disease prior to further intervention.
Ancient Respected and Modern Absorbed, Chinese Essence and Western Utility—Thoughts of the Integrated Chinese Medicine and Western Medicine
Authors: Liu Xiaofa , Li Diangui , Lu Shengda 
Published: August 2022

AbstractTraditional Chinese medicine (TCM) and Western medicine are two medical systems formed in different cultural backgrounds. The differences between them are that TCM focuses on the study of the invisible state while Western medicine focuses more on the study of the visible state of the human body; TCM pays attention to systematicity and integrity, while Western medicine pays attention to local evidence; TCM attaches importance to dialectical thinking, while Western medicine attaches importance to materialistic thinking. For the development of TCM, it is necessary to take the initiative to learn from and absorb all the advanced scientific and technological achievements in the world today. To innovate TCM, it is necessary to need to adhere to (1) the integration of “research on TCM with the thought of TCM ” and “research on TCM based on the thought of Western medicine”; (2) the integration of scientization of TCM and scientization for TCM; (3) the integration of mobilization therapy and allopathic therapy; (4) the integration of treating patients and treating diseases; (5) the integration of preventive treatment and existent disease treatment; (6) the integration of individuality and commonality; and (7) the integration of the macro and the micro.
Status of Clinical Application of Yufeng Ningxin Preparations and the Meta-Analysis of Its Efficacy and Safety in the Treatment of Cardiovascular and Cerebrovascular Diseases
Authors: Zhang Lishuang , Ma Yaxia , Wang Ying , Jiang Feng 
Published: August 2022

Abstract
Objective The objective of this study was to analyze the status of the clinical application of Yufeng Ningxin (YFNX) preparations and systematically evaluate their efficacy and safety in the treatment of cardiovascular and cerebrovascular diseases.
Methods Through searching databases of China National Knowledge Infrastructure, Wanfang, SinoMed, VIP, PubMed, Embase, and the Cochrane Library, the literature of clinical research on YFNX preparations in treating malignant tumors of cardiovascular and cerebrovascular diseases from the establishment of the databases to February 2021 was collected. The clinical randomized controlled trials and case–control studies of cardiovascular and cerebrovascular diseases treated with these preparations were analyzed. Two reviewers independently screened literature, extracted data, and assessed the risk of bias in the included studies, and meta-analysis was performed by using ReMan 5.3 software to analyze the efficacy and safety of YFNX preparations in the treatment of cardiovascular and cerebrovascular diseases.
Results A total of 29 clinical studies were finally included. The dosage forms were dropping pills, tablets, capsules, and granules. The preparations were used for the treatment of coronary heart disease, hypertension, neuropathic headache, etc. This study systematically evaluated the efficacy and safety of YFNX preparations in the treatment of coronary heart disease, hypertension, and nervous headache. A total of 1,162 cases were included in 13 studies, 582 cases of the YFNX preparation group and 580 cases of the Western medicine group. The results of meta-analysis showed that the clinical efficacy of YFNX preparations combined with the Western medicine group in the treatment of coronary heart disease and hypertension, improving electrocardiogram and reducing the frequency and duration of angina attacks, was better than that of the simple Western medicine group, and the difference was statistically significant.
Conclusion YFNX preparations are effective for coronary heart disease, hypertension, and neuropathic headache, and the adverse reactions are few.
Laparoscopic versus Open Appendectomy: A Prospective Comparative Study and 4-Year Experience in a Tertiary Care Hospital
Authors: Shaikh Aftab H. , Tandur Amarjeet E. , Sholapur Sachin , Vangal Gajanan , Bhandarwar Ajay H. , Ghosh Ahana , Rathod Abhishek 
Published: August 2022

Abstract
Background The aim of this study was to validate the pros of laparoscopic appendectomy (LA) over open appendectomy (OA) and to compare various primary outcome measures in the management of acute and recurrent appendicitis.
Study Design Prospective comparative study.
Place and Duration Between June 2015 and October 2019 in JJ Hospital, Mumbai.
Materials and Methods Total of 60 patients with acute and recurrent appendicitis were included in the study. Thirty patients underwent OA and 30 underwent LA. Both groups were comparable clinicopathologically and demographically. Various intraoperative and postoperative parameters were compared. Continuous variables were expressed as mean ± standard deviation and categorical variables were expressed as percentages. Mann–Whitney U test was used to compare continuous variables and chi-squared test was used to compare categorical variables. p-Value≤0.001 was considered to be statistically significant.
Results The median age of patients undergoing OA and LA was 24.9 and 25.2 years (p = 0.221), respectively. Female: male ratio in OA and LA was 1.30 and 1.14, respectively (p = 0.795). Mean operative duration in LA and OA group was 47.17 ± 14.39 minutes and 36.9 ± 12.33 minutes (p = 0.001), respectively. Mean length of postoperative stay in LA and OA group was 3.69 ± 0.71 days and 5.28 ± 0.63 days (p = 0.000), respectively. Median visual analogue scale score in LA and OA group was 3.5 and 5 (p = 0.001), respectively. Mean time to return to normal activity in LA and OA group was 8.13 ± 1.33 days and 10.10 ± 2.20 days (p = 0.000), respectively. About 6.66% patients in LA group and 13.33% in OA group had postoperative wound infection (p = 0.652). Mean scar scale scoring done on 30th postoperative day was 4.23 in LA and 8.23 in OA (p = 0.000).
Discussion and Conclusion LA is more promising than OA in the management of acute and recurrent appendicitis. LA offers lesser operative site pain in the postoperative period, shorter postoperative hospital stays, earlier recovery, and return to normal activities and cosmetically better scars on 30th day follow-up. No conversions or significant difference in wound related complications were seen in both groups. Prolonged intraoperative duration was the only drawback of LA.
Role of Circulating Tumor Cells in Determining Prognosis in Metastatic Breast Cancer
Authors: Dhaka Sonia , Tripathi Rupal , Doval Dinesh Chandra , Mehta Anurag , Maheshwari Udip , Koyyala Venkata Pradeep Babu , Singh Jatinderpal 
Published: August 2022

Background Circulating tumor cells (CTCs) in the peripheral blood may play a major role in the metastatic spread of breast cancer. This study was conducted to assess the role of CTCs to determine the prognosis in terms of survival in metastatic breast cancer patients.Methods This prospective study of 36 patients was conducted at the Hospital from April 2016 to May 2018. Details of each patient related to the demographic profile, tumor type, treatment, and follow-up information were recorded. The number of CTCs in the peripheral blood was measured by Celsee PREP 400 sample processing system and Celsee Analyzer imaging station.Results There was a positive correlation between the number of site of metastasis with number of CTCs (p-value < 0.001). In the patients with clinical/partial response, a significant reduction in the number of CTCs after 1 month of therapy was observed (p-value = 0.003). When the number of CTCs at baseline and 6 months were compared with the positron emission tomography response at 6 months, a statistically significant difference in CTCs in patients having partial response after 6 months was observed (p-value = 0.001). On comparison with the responder groups, a statistically significant reduction in CTCs at baseline and 6 months was observed (p-value = 0.001). Patients with CTCs less than 5 and more than or equal to 5 after 1 month of treatment had a mean progression-free survival of 11.1 months and 7.5 months (p-value = 0.04) and a mean overall survival of 11.6 and 9.6 months (p-value = 0.08), respectively.Conclusion Assessment of CTCs provides a more quantifiable response than radiographic evaluation and at a much earlier time point and is also a better predictor of survival.
Femoral Artery Cannulation Timing for a Pediatric Aortic Arch Repair
Authors: Yamamoto Tomohiro , Schindler Ehrenfried 
Published: August 2022

AbstractWe have previously introduced a blood delivery method via femoral artery cannulation to provide perfusion to the organs in the lower part of the body during pediatric aortic arch repair surgeries. In the original procedure, the femoral artery cannulation was performed after the patient had been covered with a sterile drape. Here, we suggest that the femoral artery cannulation should be performed before the patient is draped to allow optimal visibility of the target artery and puncture needle via aseptic real-time ultrasound-guided technique by reducing the inclusions between the patient's skin and ultrasound probe which attenuate the ultrasound beam.
Evaluation of Outcomes of Mucinous Ovarian Cancer Treated at a Tertiary Care Cancer Hospital in Pakistan
Authors: Hamdani Syed Abdul Mannan , Azhar Musa , Wahab Abdul , Yasmeen Tahira , Siddiqui Neelam 
Published: August 2022

Objective To evaluate the clinicopathological features and survival outcomes of mucinous ovarian cancer (MOC) patients in an Asian population.
Study Design Descriptive observational study.
Place and Duration of Study Shaukat Khanum Memorial Cancer Hospital, Lahore, Pakistan, from January 2001 to December 2016.
Methods Data of MOC were evaluated for demographics, tumor stage, clinical characteristics, tumor markers, treatment modalities, and outcomes from electronic Hospital Information System.
Results Nine-hundred patients with primary ovarian cancer were reviewed, out of which 94 patients (10.4%) had MOC. The median age was 36 ± 12.4 years. The most common presentation was abdominal distension 51 (54.3%), while the rest presented with abdominal pain and irregular menstruation. Using FIGO (The International Federation of Gynecology and Obstetrics) staging, 72 (76.6%) had stage I, 3 (3.2%) stage II, stage III in 12 (12.8%), and 7 (7.4%) had stage IV disease. The majority of patients 75 (79.8%) had early-stage (stage I/II), while 19 (20.2%) presented with advanced-stage (III & IV). The median follow-up duration was 52 months (range 1–199 months). Among patients with early-stage (I&II), 3- and 5-year progression-free survival (PFS) was 95%, while for advanced stage (III&IV), PFS was 16% and 8%, respectively. The overall survival (OS) in early-stage I&II was 97%, while for advanced stages III & IV, the OS was 26%.
Conclusion MOC is a challenging and rare subtype of ovarian cancer requiring special attention and recognition. Most patients treated at our center presented with early stages and had excellent outcomes, while advanced-stage disease had dismal results.
X-ray focusing to 62 keV by compound refractive lenses for high-pressure x-ray diffraction
Authors: Hirao Naohisa , Ohishi Yasuo 
Published: August 2022

This study describes high-energy x-ray focusing optics using compound refractive lenses (CRLs) for high-pressure x-ray diffraction (XRD) with a monochromatic x-ray beam. A CRL-based x-ray transfocator was upgraded and installed in the optics hutch at the BL10XU beamline of SPring-8. The instrument can be equipped with two types of CRLs in parallel: a newly designed aluminum (Al) CRL for x-ray energies of 40–62 keV and an existing glassy carbon CRL for those up to 40 keV. In only the Al-CRL-based x-ray transfocator, a 62 keV monochromatic x-ray beam with horizontal (H) and vertical (V) focused spots, whose sizes were 189 and 10.5 µm, respectively, and a flux of 1.32 × 1011 phs/s were generated. A polymer SU-8 CRL fabricated via deep x-ray lithography was installed to further reduce the x-ray beam size. The Al-CRL and the SU-8 CRL were combined to generate a smaller spot size of 12.5 (H) × 11.0 (V) μm2 with a flux of 3 × 1010 phs/s at 62 keV. A two-step optical configuration combining an x-ray transfocator and SU-8 CRL provides a valuable method for high-pressure XRD using a high-energy x-ray focused beam. The optical design and performance of the Al-CRL-based x-ray transfocator, its combination with the SU-8 CRL, and the first results of the focusing optics commissioning are presented here.
Egophoricity and evidentiality: Different categories, similar discourse functions
Authors: Sandman Erika , Grzech Karolina 
Published: August 2022

AbstractThis article discusses how evidential and egophoric making is used to manage knowledge in interaction. To this end, it analyzes interactional data from Wutun (mixed Sinitic, Northwest China) and Upper Napo Kichwa (Quechuan, Ecuador). Wutun has an egophoric marking system, which, according to the definition of egophoricity, encodes involvement/lack of involvement in the described event. Upper Napo Kichwa has a set of evidentials, which, according to theory, encode the source of evidence for a given proposition. The two languages are typologically unrelated. However, when we look closely at how speakers of Wutun and Kichwa use epistemic markers, we discover functional similarities not predicted by the dominant definitions of epistemicity and evidentiality. In both languages, the use of the markers is conditioned by the interpersonal context of the interaction, and speakers use egophoric and evidential marking to signal their epistemic rights and responsibilities with respect to other speech-act participants.
The manipulations of surface anisotropy and interfacial Dzyaloshinskii–Moriya interaction by an amorphized oxide Ta capping layer
Authors: Cho Jaehun , Lee Chan-Kang , Kim Joonwoo , Kim June-Seo , You Chun-Yeol 
Published: August 2022

Abstract
The perpendicular magnetic anisotropy (PMA) and the interfacial Dzyaloshinskii–Moriya interaction (iDMI) energy density in Ta/Pt/Co/plasma-enhanced oxide layer systems are systematically investigated by using the magneto-optical Kerr effect and Brillouin light scattering spectroscopy. The wedge-type top Ta layer is grown and the in-situ plasma-enhanced oxidation process is performed to form an amorphized oxide layer. Consequently, the surface anisotropy energy is significantly reduced in a certain TaO
x
thickness range and the iDMI energy density is relatively maintained. From these systematic experiments, we reveal that the PMA energy is strongly affected by both top and bottom interfaces, but the contribution from the bottom interface is dominant for the iDMI energy density.
Fabrication of g-C3N4/N,Fe co-doped CQDs composites: in situ decoration of g-C3N4 with N-CQDs and Fe and efficient visible-light photocatalytic degradation of tetracycline
Authors: Mou Zhigang , Chen Ting , Tao Yang , Gao Yang , Sun Jianhua , Lei Weining 
Published: August 2022

Abstract
Herein, for the first time, g-C3N4/N,Fe co-doped carbon quantum dots (CN/N,Fe-CQDs) composites were fabricated by a two-step fabrication route. N,Fe-CQDs were obtained via facile pyrolysis of ammonium ferric citrate. Through thermal condensation of the synthesized N,Fe-CQDs and urea, CN/N,Fe-CQDs composites were successfully fabricated for highly efficient photocatalytic degradation of tetracycline (TC). The optimized CN/N,Fe-CQDs composite obtained the degradation efficiency of 81.0% after 40 min visible-light illumination, and its apparent rate constant was 3.41 times higher than that of pure g-C3N4. The remarkable enhancement of photodegradation activity is mainly attributed to the synergetic effect of N-CQDs and Fe co-decoration in CN/N,Fe-CQDs arising from the incorporation of N,Fe-CQDs into the g-C3N4 matrix, which could increase the specific surface area, wide visible-light absorption range, and accelerate separation and transfer of interfacial charge. The active species capture experiments and electron spin resonance technique testified that ‧O2
−, ‧OH, 1O2 and h+ were all involved in the degradation of TC in the photocatalytic process. According to the result of mass spectrometry, TC underwent hydroxylation, demethylation, N-demethylation, deamination, dehydroxylation, ring opening processes, and was ultimately mineralized into CO2 and H2O. This research can provide a new understanding of the roles played by non-metal and metal ions co-doped CQDs in photocatalytic system and open up a new way to develop highly efficient photocatalysts for TC degradation.
Ground state and thermodynamic properties of the coupled double-Ising model: application to rare-earth tetraborides
Authors: Farkašovský Pavol , Regeciová Lubomíra 
Published: August 2022

Abstract
A combination of the standard Metropolis algorithm and the parallel tempering method is used to study ground-state and thermodynamic properties of the coupled double Ising (CDI) model on the Shastry–Sutherland lattice (SSL). This model is derived from the complex spin-electron model, in which electrons described by the Hubbard model and spins described by the Ising model interact via the anisotropic spin-dependent interaction of the Ising type, under the following three conditions: (a) the Hubbard interaction between electrons in the conduction band is sufficiently large; (b) the number of conduction electrons is equal to the number of the lattice points; (c) there is the easy axis spin anisotropy in the system. The model is solved numerically for the selected combinations of spins from the electron (

s
=
1

/

2

) and spin (

S
=
1
,
3

/

2
,
2

) Ising branch which represent very realistically the situation in TmB4, ErB4 and HoB4 compounds, where in addition all three conditions are simultaneously satisfied. It is shown that the interlpay between the electron and spin branch of the CDI model leads to the suppression of the 1/3 magnetization plateau (the main magnetization plateau found in the ordinary Ising model on the SSL) and the stabilization of magnetization plateaus with

m
∼
1

/

2

, which is in perfect agreement with the experimental measurements in TmB4 and ErB4 compounds. A nice correspondence between theoretical and experimental results is also obtained for the temperature dependence of the specific heat capacity, where the low-temperature peak corresponding to the electron branch of the CDI model is followed by high-temperature peak of the spin branch. This opens a new route for exploring the physics of other complex spin-electron systems in which the above-mentioned conditions (a)–(c) are fulfilled.
Radius of analyticity of solutions to compressible Navier–Stokes–Korteweg system
Authors: Deng Wen , Paicu Marius 
Published: August 2022

Abstract
We study the analyticity and Gevrey regularity for the solutions to the compressible Navier–Stokes–Korteweg system. It was observed by Charve et al (2021 Indiana Univ. Math. J.
70 1903–44) that this system has the full parabolicity property due to the coupling of the equations given by the Korteweg capillarity term, which allows them to prove the analyticity of the solutions in the whole space

R

d

with radius bounded from below by

C

t

. In this paper, we improve this lower bound, motivated by the works of Chemin et al (2020 Math. Res. Lett.
27 1631–43) concerning the classical Navier–Stokes system. We also study the compressible Navier–Stokes–Korteweg system with periodic boundary condition and we show that the radius of analyticity for the mild solution is bounded from below by Ct.
Global existence and decay of the inhomogeneous Muskat problem with Lipschitz initial data
Authors: Alonso-Orán Diego , Granero-Belinchón Rafael 
Published: August 2022

Abstract
In this work we study the inhomogeneous Muskat problem, i.e. the evolution of an internal wave between two different fluids in a porous medium with discontinuous permeability. In particular, under precise conditions on the initial datum and the physical quantities of the problem, our results ensure the decay of the solutions towards the equilibrium state in the Lipschitz norm. In addition, we establish the global existence and decay of Lipschitz solutions.