bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALYSIS THE EFFECT OF SENSORY INTERVENTION ON PATIENT’S ANXIETY ACCORDING TO MAGNETIC RESONANCE IMAGING-ANXIETY QUESTIONNAIRE (MRI-AQ) AND HEART RATE IN MRI LUMBAL EXAMINATION
Authors: Andeizi Tifan Nata , Devianti Putri Berliana , Muhaimin  , Muqmiroh Lailatul , Setiawati Rosy 
Published: August 2022

Background: The use of MRI as a non-invasive diagnostic radiological examination modality is painless. However, patients may experience claustrophobia and anxiety. Sensory intervention is a method of providing sensory stimulation to an individual, which is expected to reduce the anxiety. Purpose: To determine the effect of the sensory intervention on the anxiety level of patients using an intervention scent by inhalation and intervention sound based on heart rate and MRI-AQ in patients with MRI lumbal examination. Method: 24 samples were divided into three groups: intervention scent, combination intervention scent-sound, and control, with eight samples each. Intervention scent is given using lavender essential oil as aromatherapy, drop three drops on the mask, then put the mask on for 5 minutes before the examination until the examination is completed. Intervention sound is given by playing music (nature-sound) during the examination. Result: Sensory intervention, specifically the use of combination intervention scent-sound, significantly reduces anxiety in patients during MRI lumbal examination significantly p = 0.004 (p<0.05). Conclusion: The use of a combination between lavender and nature-sound as media for sensory intervention has a positive effect on reducing anxiety during MRI lumbal examination based on heart rate. Due to the easy administration of this aromatherapy and the minimal risk for this treatment, it is recommended that it is applied to reduce anxiety during MRI.
Influence of succinic acid on <i>Oenococcus oeni</i> and malolactic fermentation
Authors: Torres-Guardado Rafael , Rozès Nicolas , Esteve-Zarzoso Braulio , Reguant Cristina , Bordons Albert 
Published: August 2022

As a consequence of the alcoholic fermentation carried out by yeasts in wine, several compounds can be delivered to the medium, promoting or inhibiting the malolactic fermentation (MLF) and the lactic acid bacteria, mainly Oenococcus oeni. Succinic acid is one of these compounds and is an example of the interaction between yeasts, including non-Saccharomyces species, and O. oeni. However, the influence of succinic acid on the MLF has been researched very little as yet. In this work, we study the influence of succinic acid and pH on O. oeni CH11 and PSU-1 strains, both during MLF and in resting cell experiments. Moreover, we analysed the relative expression of some significant genes related to stress and malolactic activity to determine how the O. oeni strains were affected by the succinic acid. The results showed that the succinic acid could act as an MLF inhibitor at concentrations higher than 1 g/L, but it can be beneficial at 0.5 g/L. This variable effect also depends on the strains and other winemaking conditions, mainly pH, which influences the dissociated and undissociated forms of both acids. The inhibiting effect of succinic seems clearer when it is at a molar concentration higher than that of L-malic acid. Experiments with resting cells have confirmed that O. oeni consumes less L-malic acid when succinic acid is higher than 1 g/L. Genetic expression experiments showed that in the presence of succinic acid (2 g/L), gene hsp18 encoding stress protein was up-regulated in strain CH11, suggesting a good response and adaptation of this strain to stress. On the other hand, genes mleA and mleP, which are related to malolactic activity, were not affected by succinic acid, except for strain PSU-1 at pH 4.0. Further research is necessary to understand better the effects of succinic acid on O. oeni and MLF.
Exploring Socioeconomic Vulnerability of Traditional Market Sellers To COVID-19 Pandemic
Authors: Kanza Umairoh Mutia , Mei Estuning Tyas Wulan 
Published: August 2022

<p><em>Traditional market as a major resource of inexpensive goods for countless middle and low-income classes as well as an essential source of livings for many persons is one of the crowded places having high risk of SARS-CoV-2 virus (COVID-19) transmission. In a one hand, working in packed, precarious conditions, and becoming sick due to COVID-19 will have devastating effects on sellers’ entire households. In the other hand, markets must remain open so that customers may buy goods and sellers and their supply chains may preserve their livings. By taking location in Gede Market, Cilacap Regency, Central Java Province, this research aims (i) to analyze the social and economic vulnerability of sellers to COVID-19 pandemic, and (ii) to identify the coping strategy of sellers to deal with COVID-19 pandemic. Quantitative and qualitative data were retrieved towards 50 traditional market sellers and related keypersons. AHP (Analytical Hierarchy Process) was used to measure the weight of each variable and factor of social and economic vulnerability. Multi scenarios analysis of socioeconomic vulnerability were conducted (social scenario, economic scenario, and equal scenario) resulting 18 percent, 48 percent, and 34 percent respondents having high level of vulnerability, respectively. There are as many as 18 percent of respondents who are always categorized in high vulnerability regardless of the scenario. Different coping strategies used by sellers to deal with economic problems during COVID-19 Pandemic such as reducing the number of commodities, conducting online selling, saving expenses, borrowing money, reducing the number of workers, transforming the fresh food commodities (perishable goods) into frozen food (more durable goods), and selling the commodities around neighborhood. However, this study also observed that some respondents did not undertake any coping strategy.</em><strong></strong></p>
HUBUNGAN ANTARA REGULASI DIRI DENGAN KESIAPAN SEKOLAH ANAK USIA 5-6 TAHUN
Authors: Nugraheni Anindya , Rahmawati Anayanti , Pudyaningtyas Adriani Rahma 
Published: August 2022

<p>Penelitian ini bertujuan untuk mengetahui hubungan antara regulasi diri dengan kesiapan sekolah anak usia 5-6 tahun. Desain penelitian ini adalah Penelitian ini akan menggunakan pendekatan kuantitatif dengan jenis penelitian korelasi. Sampel penelitian sejumlah 100 anak usia 5-6 tahun di TK segugus 5 Kenangan, Banaran, Boyolali yaitu TK Aisyiyah 1 Boyolali, TK Aisyiyah 5 Boyolali, TK Aisyiyah 6 Boyolali, TK Almabrur Boyolali, TK Muslimat NU 1 Boyolali dan TK Kemala Bhayangkari 62. Hasil analisis data menunjukkan bahwa pertama, nilai koefisien korelasi sebesar 0,591 dan menunjukkan hubungan positif yang artinya apabila kesiapan sekolah semakin baik, maka, regulasi diri anak usai 5-6 tahun semakin baik pula. Kedua, uji hipotesis menunjukkan angka 0,000&lt;0,05 maka H<sub>0 </sub>ditolak. Hal ini membuktikan bahwa kesiapan sekolah dengan regulasi diri anak usia 5-6 tahun. Regulasi diri berhubungan dengan kesiapan sekolah karena regulasi diri merupakan salah satu bekal anak untuk bisa beradaptasi dengan lingkannya sehingga mendukung kesiapan sekolah anak. Hal tersebut penting karena anak yang telah memiliki kesiapan untuk sekolah akan memperoleh keuntungan dan kemajuan dalam perkembangan selanjutnya. Selain itu, regulasi diri anak-anak prasekolah, termasuk kepatuhan dan kontrol diri mereka, dapat memengaruhi keberhasilan siswa seperti yang diharapkan, anak-anak untuk mengikuti peraturan kelas dan arahan guru, berbagi mainan, dan menunggu giliran mereka.</p><p> </p>
HADITH AND PROPHET MUHAMMAD AUTHORITY: Understanding of Jonathan A.C. Brown
Authors: Nafisah Lailiyatun 
Published: August 2022

<p>Hadith is frequently the subject of research by Muslim academics and Westerners. Both Muslim academics and orientalists have debated the legitimacy of the hadith for a long time. Jonathan AC Brown is a western Muslim scholar who contributes to rationally explaining the study of hadith so that it is easily accepted by beginners; his work demonstrates his commitment to the study of Islamic studies. This study follows a library research approach in which Jonathan Brown's book "<em>Hadith: Muhammad's Legacy in the Medieval and Modern World</em>" is utilized as the primary reference source, which is then supplemented with scholarly publications and journals on Jonathan Brown. The author used the descriptive analysis technique. According to the findings of this study, a hadith is a report about the Prophet consisting of the main text that describes his words or actions, the way of transmission (isnad) that serves to convey, and finally the giver. The authority of Muhammad is that of a Prophet who functions as a teacher, leader, and role model, as well as someone who has knowledge of the future. However, because the Prophet was an ordinary person, he did not have full authority in some matters.</p><p class="06IsiAbstrak">[<strong>Hadis dan Otoritas Nabi Muhammad</strong>:<strong> Pemahaman Jonathan A.C. Brown</strong>. Hadis sering menjadi bahan kajian yang tidak hanya dilakukan oleh sarjana muslim, namun juga barat. Berbagai pro dan kontra akan keaslian hadis telah lama berkembang, baik sarjana muslim maupun orientalis. Jonathan A.C Brown, merupakan sarjana muslim barat yang berkontribusi dalam menjelaskan kajian hadis secara rasional sehingga mudah diterima kaum pemula, karya yang dihasilkannya merupakan bukti keseriusan dalam kajian studies islamic. Penelitian ini merupakan model penelitian kepustakaan (library reseach) dimana, buku “<em>Hadith: Muhammad’s legacy in the medieval and modern world</em>” Brown dijadikan sebagai sumber rujukan utama, kemudian didukung oleh karya ilmiah dan jurnal yang berkaitan dengan Jonathan Brown. Penulis menggunakan metode analisis deskriptif. Hasil penelitian ini menunjukan bahwa hadis adalah adalah laporan tentang Nabi, yang terdiri dari teks utama untuk menjelaskan kata- kata atau tindakannya, rantai transmisi (isnad) yang berufngsi untuk mengkomunikasikan, kemudian penyampai. Otoritas Muhammad merupakan seorang Nabi yang memiliki peran sebagai guru, panutan, dan teladan, dan seseorang yang mampu memiliki akses mengetahui masa depan. Akan tetapi Nabi adalah seorang manusia biasa sehingga tidak secara keseluruhan menjadi otoritatif dalam beberapa hal.]</p>
REVIEWING RELIGIOUS UNDERSTANDING OF THE MARRIAGE HADITH
Authors: Nurul Nurul , Khoiril Waro Mochamad Tholib 
Published: August 2022

<p>Intellectual discourse on women especially on marriage in Islamic tradition are dominated by patriarchal perspective. Islamic Intellectual treasures such as hadith and its explanation, exegesis, books, scholar and their intellectual products showed us how ancient Arabic patriarchal pattern existed. On the other hand, modernity led civilization to the values of equity, equality, human right and democracy against inequity, inequality, monarchy and individual cult. Problems of inequity appeared much on women discourse in Islamic tradition. Thousands of hadiths were identified recorded by men in patriarchal culture. It made gender issues in Islamic tradition are still sensitive. This article tries to reconstruct the discourse in one of the popular hadiths in marriage in order to explore the possibility of studying the meaning of a more moderate hadith. By using Juynboll's common link, the author finds the hadith narrowed to one name, namely A'masy which is then categorized as a common link in this study. In addition to having implications for the emergence of certain names as common links, this study also reviews further implications regarding the relevance of broader studies in hadith studies; urgent efforts to be made in order to place hadith as a source of more contextual and moderate religious discourse.</p><p>[<strong>Tinjauan Pemahaman Agama Terhadap Hadis Pernikahan</strong>. Wacana intelektual tentang perempuan khususnya perkawinan dalam tradisi Islam didominasi oleh perspektif patriarki. Kekayaan Intelektual Islam seperti hadits dan penjelasannya, tafsir, kitab-kitab, ulama dan produk intelektualnya menunjukkan kepada kita bagaimana pola patriarki Arab kuno ada. Di sisi lain, modernitas membawa peradaban pada nilai-nilai kesetaraan, kesetaraan, hak asasi manusia dan demokrasi melawan ketidakadilan, ketidaksetaraan, monarki dan kultus individu. Masalah ketidakadilan banyak muncul pada wacana perempuan dalam tradisi Islam. Ribuan hadis diidentifikasi dicatat oleh laki-laki dalam budaya patriarki. Hal itu membuat isu gender dalam tradisi Islam masih sensitif. Artikel ini mencoba merekonstruksi wacana dalam salah satu hadis populer dalam pernikahan guna menjajaki kemungkinan mengkaji makna hadis yang lebih moderat. Dengan menggunakan common link Juynboll, penulis menemukan hadits tersebut dipersempit menjadi satu nama, yaitu A'masy yang kemudian dikategorikan sebagai common link dalam penelitian ini. Selain berimplikasi pada munculnya nama-nama tertentu sebagai common link, kajian ini juga mengkaji implikasi lebih lanjut mengenai relevansi kajian yang lebih luas dalam kajian hadis; Upaya mendesak dilakukan untuk menempatkan hadis sebagai sumber wacana keagamaan yang lebih kontekstual dan moderat.]<em><br /></em></p>
Interactive Effects of Melatonin and Salicylic Acid on Brassica napus Under Drought Condition
Authors: Ilyas Noshin , Rafique Noman , Aqeel Muhammad , Raja Naveed Iqbal , Shabbir Ghulam , Ajaib Muhammad 
Published: August 2022

Abstract
AIMS:It is imperative to understand the synergetic actions of melatonin (MET) and salicylic acid (SA) in counteracting the negative effects of drought. A pot experiment was performed to investigate the interactive effects of exogenously applied MET and SA on morphology, physiology, and biochemical characteristics of drought stressed canola (Brassica napus). METHODS:Two cultivars (Super canola and Faisal canola) were used. MET (0.1 µM) and SA (0.50 mM) were applied as seed priming, and as foliar spray. Plants were exposed to severe drought stress (45% field capacity) at reproductive stage. RESULTS:Subjecting canola cultivars to drought caused significant reduction in shoot length (19%), plant fresh (15%) and dry (17%) biomass, yield (30%) and photosynthetic attributes (43%). Increased activity of free amino acids (20%), total soluble sugars (5%), and different antioxidant enzymes like catalase (27%), peroxidase (23%), superoxide dismutase (20%) and ascorbate peroxidase (35%) were recorded under drought. Seed priming, and foliar application of MET and SA increased growth and yield of canola cultivars. Priming of seeds with MET as well as synergetic application of MET priming and SA foliar spray were the most effective treatments among all, showing the greatest growth criteria (22% increase in plant height, 46% in fresh and 40% in dry biomass), yield components (49%) and endogenous MET (17%) and SA (16%) activity. Super canola cultivar showed better growth than Faisal canola. CONCLUSION:Study showed that synergetic application of MET and SA has the potential to induce stress resistance and enhance canola plants growth under drought.
5′-tRNAGly(GCC) halves generated by IRE1α are linked to ER stress response
Authors: Yeom Ji-Hyun , Shin Eunkyoung , Ha Yoonjie , Joo Minju , Jin Hanyong , Liu Haifeng , Kim Daeyoung , Kim Yong-Hak , Kim Hak Kyun , Kim Jeongkyu , Kim Hong-Man , Ryu Minkyung , Kim Keun Pil , Hahn Yoonsoo , Bae Jeehyeon , Lee Kangseok 
Published: August 2022

Abstract

Transfer RNA (tRNA) halves (tRHs) have various biological functions. However, the biogenesis of specific 5′-tRHs under certain conditions remains unknown. Here, we report that inositol-requiring enzyme 1α (IRE1α) cleaves the anticodon stem-loop region of tRNAGly(GCC) to produce 5′-tRHs (5′-tRH-GlyGCC) with highly selective target discrimination upon endoplasmic reticulum (ER) stress. We observed IRE1α expression-dependent 5′-tRH-GlyGCC production in human cancer cells. Levels of 5′-tRH-GlyGCC were positively correlated with the degree of cancer cell proliferation both in vitro and in vivo; this effect required co-expression of two nuclear ribonucleoproteins, HNRNPM and HNRNPH2, which we identified as binding proteins of 5′-tRH-GlyGCC. In addition, 5′-tRH-GlyGCC modulated mRNA isoform biogenesis. Furthermore, under ER stress in vivo, we observed simultaneous induction of IRE1α and 5′-tRH-GlyGCC expression in mouse organs and a distantly related organism, Cryptococcus neoformans. Thus, collectively, our findings indicate an evolutionarily conserved function for IRE1α-generated 5′-tRH-GlyGCC in cellular adaptation upon ER stress.
Redox-dependent Structural Origins of the Temperature Threshold and Sensitivity in the TRPV3 Bio-thermometer
Authors: Wang Guangyu 
Published: August 2022

Abstract
The DNA hairpin with a limited size or strength is sensitive to temperature. However, it is unclear if thermosensitive TRP channels also use the temperature-dependent little hairpin sizes or strengths to govern their temperature thresholds and sensitivity. Here, graph theory was used as a novel tool to test this hypothesis by analyzing the redox- and state-dependent cryo-electron microscopy structures of mouse TRPV3 with or without the Y564A mutation at different temperatures. The results showed that the biggest little hairpin with the minimal topological loop size and strength determines the temperature threshold while a change in the total minimal little hairpin sizes upon a change in the total little hairpin-dependent non-covalent interactions along the channel gating pathway governs the temperature sensitivity. This size- and strength-dependent hairpin thermodynamics may tune the thermal activity and sensitivity of biological macromolecules.
Biodegradable active packaging material containing grape seed ethanol extract and corn starch/к-carrageenan composite film
Authors: Wang Cuntang , An Xuanzhe , Li Ziyu , Lu Yueyi , Gao Zengming , Tian Shengxin 
Published: August 2022

Abstract
A biodegradable packaging film with antioxidant and antibacterial activity was developed by adding grape seed ethanol extract (1%、3%、5% per g of starch) to corn starch/κ-carrageenan (CS/кC) complex film made using the solvent casting method. The κ-carrageenan is a promising film-forming polymer with highly elastic and adhesive properties. The addition of Grape seed ethanol extract (GSE) enhanced the water vapor permeability, break elongation, and opacity of the film, and this is related to the excellent dispersion of GSE in CS/кC film observed by scanning electron microscope, and the formation of intermolecular hydrogen bond between GSE and CS proved by FT-IR. Thermogravimetric analysis showed that the CS/кC -5% GSE film has a high glass transition temperature (121.65℃). With the increase of GSE content, it improved the antioxidant capacity (DPPH radical scavenging 26.5% and ABTS radical scavenging 45.0%) and antibacterial activity (Bacteriostatic circle diameter of E. coli 12.78 ± 0.42 mm and S. aureus strains 13.52 ± 0.66 mm) of CS/кC films. Simulated food packaging experiments presented that CS/кC-GSE film significantly reduced the peroxide value of lard (P < 0.05). The above results indicate that the GSE can be used as a food-grade packaging material and has a good application prospect in the food industry.
Provable Lightweight Hybrid Proxy Re-Encryption Scheme without Pairings for Internet of Things
Authors: Abouelkeir Eman 
Published: August 2022

Abstract
Cisco originated a term fog computing which decentralized computing process on the cloud central to be closer to IOT data. Fog computing provides an efficient data storage and processing. Fog computing still suffer from some security and privacy. Security problems solved by proxy re-encryption schemes but it suffers from heavy computational operations because of using so many paring operations in delegation and delegated sides. Parings operations causes heavy computations. This paper suggests a new hybrid proxy re-encryption scheme without parings using both the symmetric and asymmetric cryptography schemes. The security proof of the proposed scheme has been done under Indistinguishability-Chosen Plaintext Attack. The suggested scheme is highly computationally efficient when compared with other schemes in literature.
HuR-induced CDK2 translational enhancement aggravates oral tongue squamous carcinoma
Authors: duan Yangfang , wei Youchun , wang Yunxia 
Published: August 2022

Abstract
Background: Oral tongue squamous carcinoma(OTSC) is an extremely malignant tumor specifically characterized by CDK2-mediated cell cycle perturbation.However,the underlying mechanism is poorly understood. HuR,an ubiquitously expressed member of the embryonic lethal abnormal vision family, participated in various malignent cancer. Therefore, this study aimed to explore the relationship of HuR and CDK2 in OTSC.Materials and methods: SCC25 cell line was sellected in vitro assay for the impact of HuR knockdown on tumor proliferation or CDK2 expression. IHC or mRNA levels of HuR and CDK2 expression were evaluated in malignent or benign lession tissue. Student’s t-test is used for two-group comparisons, and the one-way ANOVA for multiple group comparisons.Results:HuR knockdown reduced SCC25 proliferation, led to cell cycle arrest and dampened the colony formation. Mechanismly, HuR promoted CDK2 translation through binding to 3’untranslated regions. The luciferase activity assay futher authenticated the ARE-mediated HuR regulation on CDK2. Moreover, IHC results indicated that HuR expression exhibited progessive increase in the cases of pathological grade, accompanied by more cytoplasm distribution.Clinal datas demonstrated that the higher expression of HuR and CDK2 indicated poor prognosis and both had positive correlation.Conclusions: our study provides a compelling role of HuR in controlling the progression of OTSC by regulating CDK2 dependent cell cycle. These findings may provide a new therapeutic target for OTSC.
Construction of a ternary staggered heterojunction of ZnO/g-C3N4/AgCl with reduced charge recombination for enhanced photocatalysis
Authors: Chen Haodong , Shu Qing 
Published: August 2022

Abstract
In this study, a series of ternary composite photocatalysts ZnO/g-C3N4/AgCl(x) (x is the amount of AgCl added, x=0.05, 0.1, 0.15 g) were synthesized, and various characterization methods were used to analyze the morphology, structural and photochemical properties of the above samples. The photocatalytic activity of the obtained samples was evaluated by degrading rhodamine B (RhB) and acid orange (AOⅡ) using a xenon light source (500 w) as a simulated light source. The results shown that within 60 min, the degradation rate of ZnO/g-C3N4/AgCl(0.1 g) is 99%, which is much higher than the 38% degradation rate of g-C3N4. After three cycles, the degradation efficiency of RhB and AOII by ZnO/g-C3N4/AgCl(0.1 g) can still reach 91% and 95%, respectively. Based on the electronic structure analysis of DFT calculations, it is found that a staggered heterojunction structure is formed between g-C3N4, ZnO and AgCl. The enhanced photocatalytic activity of the ternary composite is mainly attributed to the efficient separation of charge carriers through the synergistic removal of photogenerated electrons in g-C3N4 by ZnO and AgCl. Radical trapping experiments confirmed that •O2− and h+ were the main active species in the reaction system. As a visible light-responsive catalyst, ZnO/g-C3N4/AgCl can be effectively applied to the degradation of organic dye pollutants and has broad application prospects.