bluuebunny/crossref_metadata_2025_split huggingface dataset:
Non-invasive focalized stimulation in deep brain using the spatially symmetric array
Authors: Fang Xiao , Yun Chen , Zeng Chaoxu , Ding Hongfa , Huang Yongheng , Liu Wei , Luo Yaoyao 
Published: November 2022

As a non-invasive neuromodulation technology, transcranial magnetic stimulation (TMS) shows great potential in the treatment of mental diseases. Using TMS to stimulate deep brain targets has significant scientific research value for the exploration of the causes of psychiatric diseases. However, the focalized induced electrical field (E-field) generated by traditional TMS coils or coil arrays is largely restricted to superficial cortical targets. To achieve focalized stimulation in the deep brain, a novel spatially symmetric array based on curved θ-type coils (the θ-SSA) is proposed in this paper. Four θ-type coils in the array are symmetrical to the YZ and XZ planes. Each θ-type coil is placed tangent to the human scalp and bent away from the human head to reduce the non-longitudinal component accumulation of the induced E-field and enhance the stimulation focalization. The finite-element method is used to obtain the 3D spatial distributions of the intracranial induced E-field generated by the proposed array. Results show that the θ-SSA can form an obvious focusing area in the deep brain 11 cm below the scalp. Under identical stimulation current excitation, the θ-SSA can increase the intracranial longitudinal attenuation ratio by 77% compared to the traditional TMS coil. In addition, when generating the same focusing area, the stimulation depth of the θ-SSA is 1.67 times deeper than that of the traditional TMS coil. Meanwhile, the proposed array can dynamically steer the intracranial stimulated area, and the spatial coordinates of the intracranial stimulation target point can be flexibly and continuously adjusted when changing the stimulation current parameters applied to the array. An anatomically realistic human head model with gray matter is employed in this paper to verify our method.
Expressing the existence of an event with ‘you(to have) + VP’ in Taiwan Mandarin
Authors: Collart Aymeric , Su Hung-Kuan 
Published: November 2022

AbstractThe verbyou‘to have’ in standard Mandarin is typically followed by a noun.Youcan also take a VP as its complement (‘you+ VP’) in several varieties of Mandarin. However, the function associated with it is still under debate: ‘you+ VP’ has been analyzed as expressing past tense, perfective aspect, perfect aspect, or realis mood. This paper assesses these analyses by conducting a corpus-based investigation of ‘you+ VP’ on the PTT platform and by looking at different morphosyntactic environments in which it is used. The data favor analyzing ‘you+ VP’ as expressing an assertive modality meaning (the situation is considered true in the real world by the speaker). This analysis corroborates with the high frequency of ‘you+ VP’ in assertive environments (e.g., after factual verbs in embedded clauses, with attitudinal adverbs of truth value, among others). Conversely, taking ‘you+ VP’ as indicating past tense or perfective aspect is challenged by the present data, and the perfect aspect analysis cannot explain all the environments in which ‘you+ VP’ is used. This paper provides new insights regarding the morphosyntactic use of ‘you+ VP’ and sheds light on the meaning this construction encodes.
(Re)chronotopizing the pandemic
Authors: Catedral Lydia 
Published: November 2022

Abstract
In this article I apply the notions of chronotope and (re)chronotopization to
the case of grassroots, migrant domestic worker (MDW) led activism during the COVID-19 pandemic in Hong Kong. I compare the
chronotopes that are produced by the Hong Kong government with those produced by migrant-led organizations to understand how
migrants are marginalized and how they resist this marginalization. More specifically, I show how the spatiotemporal
configurations of “home,” “days off,” and “the time of COVID-19 in Hong Kong” are rechronotopized – that is, reimagined,
remoralized and rematerialized – through the discourses and actions of these grassroots organizations. I use this data and
analysis to reflect on how the notion of rechronotopization can account for the social processes involved in activism more
broadly; and to draw attention to the dialectic relationship between differently scaled chronotopic materialities and morally
loaded chronotopic imaginaries.
A precise measurement method for tube endpoints based on spatial geometry and perspective projection model
Authors: Zhao Hao , Xia Renbo , Chen Yueling , Zou Hangbo , Zhang Tao 
Published: November 2022

Abstract
Tubes are widely used in the aerospace field for such things as engines, fuel pipelines, cooling systems, etc. To improve manufacturing efficiency and accuracy, researchers develop multi-camera vision methods for measuring tube geometry parameters. However, these methods cannot measure the exact position of the endpoints of the tube, because the projection points of the tube endpoints have no obvious texture features in the image. To solve the above problem, a precise measurement method for tube endpoints based on spatial geometry and perspective projection model is proposed in this paper. First, we establish a Plücker coordinate system, which treats the end of the tube as a cylinder. Then, several line equations parallel to the center line are calculated on the surface of the cylinder and their intersections with the end face are obtained on these lines, which refers to the optical center of the camera, the radius of the tube, and etc. These intersections are projected onto the centerline and optimized to get the endpoint. Finally, we build a multi-camera vision measurement system consisting of ten industrial cameras to verify the effectiveness of the proposed method. Extensive experiments have shown that the average error of this method is within 0.1 mm, and the standard deviation is within 0.08 mm, which proves the superiority of our proposed method.
Generalized Hardy operators
Authors: Bui The Anh , D’Ancona Piero 
Published: November 2022

Abstract
Consider the operator on

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the operator is non negative and selfadjoint. We prove that fractional powers

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for s ∈ (0, 2] satisfy the estimates

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for suitable ranges of p. Our result fills the remaining gap in earlier results from Killip et al (2018 Math. Z.
288 1273–98); Merz (2021 Math. Z.
299 101–21); Frank et al (Int. Math. Res. Not.
2021 2284–303). The method of proof is based on square function estimates for operators whose heat kernel has a weak decay.
Wearable ultraviolet sensing fibers embedded with carbon nanotubes and zinc oxide nanowires
Authors: Yang Jonguk , Jeong Sang-Mi , Seo Keumyoung , Lim Taekyung , Ju Sanghyun 
Published: November 2022

Abstract
Owing to the increasing interest in personal health, the real-time measurement of the exposure to ultraviolet (UV) rays during outdoor activities is a key technology that could be widely applied in the field of smart healthcare. Although wearable sensors that respond to UV intensity are being investigated, the development of sensors with stable durability and excellent sensing characteristics, despite movements, such as bending and exposure to external factors, including sweat and rain, is insufficient. In this study, we fabricated a wearable UV fiber sensor by embedding conductive carbon nanotubes (CNTs) and UV-sensitive zinc oxide nanowires (ZnO NWs) into highly elastic spandex fiber via a simple dipping-drying procedure. The ZnO NWs and CNTs coated in the form of a network inside the strands that constitute the spandex fiber enhanced the stability of the UV sensing measurements despite external changes, such as bending. In addition, by coating hydrophobic (3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodecyl)phosphonic acid onto the ZnO NWs, the current distortion of the UV sensing channel due to contact with liquid could be prevented. It was confirmed that the fiber-based UV sensor, in which ZnO NWs and CNTs are networked, responds sensitively to UV in an environment with exposure to water or sweat.
3D printed flexible wearable sensors based on triply periodic minimal surface structures for biomonitoring applications
Authors: Imanian Mohammad Ebrahim , Kardan-Halvaei Mostafa , Nasrollahi Fatemeh , Imanian Ali , Montazerian Hossein , Nasrollahi Vahid 
Published: November 2022

Abstract
Soft piezoresistive wearable conductors have led to a paradigm shift in the monitoring of human bodily motions. Cellular additively manufactured conductors are promising piezoresistive components as they offer mechanical tunability and provide controllable percolation pathways. In the present study, we engineer high surface-area cellular structures with the triply periodic minimal surface (TPMS)-based architectures to tailor their piezoresistive response for use in wearable devices. A simple and economical fabrication process is proposed, wherein a fused deposition modeling 3D printing technique is utilized to fabricate flexible thermoplastic polyurethane (TPU) cellular structures. Interconnectivity of TPMS designs enables the coating of a continuous graphene layer over the TPU internal surfaces via a facile dip-coating process. The effects of pore shape on piezoresistivity are studied in four different TPMS structures (i.e. Primitive, Diamond, Gyroid, and I-WP). Mechanical properties of sensors are evaluated through experimental procedures and computation methods using finite element analysis of the Mooney–Rivlin hyperelastic model. The piezoresistive performance of sensors exhibits durability under cyclic compression loading. Finally, we conclude that the Primitive structure offers suitable piezoresistive characteristics for sensing of walking, whereas the Diamond structure presents favorable results for respiration monitoring.
Traceability for nuclear medicine: the status of primary radioactivity standards
Authors: Judge S M , Coulon R M , Cox M G , Karam L , Knoll P , Michotte C , Msimang Z , Zimmerman B E 
Published: November 2022

Abstract
The medical use of radionuclides depends on the accurate measurement of activity (Bq) for regulatory compliance, patient safety, and effective treatment or image quality. In turn, these measurements rely on the realization of primary standards of activity by national metrology institutes, with uncertainties that are fit for purpose. This article reviews the current status of primary standards of activity for radionuclides used in medical imaging and therapy applications. Results from international key comparisons carried out through the International Bureau of Weights and Measures transfer instruments (SIR and SIRTI) are used to verify that standards for a variety of radionuclides are consistent and conform with practitioners’ expectations.
Dual energy-based quantification method for determination of breast microcalcification types
Authors: Kim H. , Lee M. , Kim H.-J. 
Published: November 2022

Abstract
The purpose of this study is to distinguish and characterize breast microcalcification types (benign and malignant) non-invasively using photon-counting spectral mammography. In this study, a photon-counting spectral mammography system was simulated using Geant4 application for tomographic emission (GATE) tool. Based on the photon-counting detector, dual-energy images were obtained using two energy bins. Calcium oxalate and calcium hydroxyapatite were used for benign and malignant microcalcifications, respectively. As a quantitative characteristic evaluation for two types of microcalcification related to etiology, an analytical model was implemented for the determination of the calcium/phosphorus mass ratio (mCa/mP) based on the dual-energy method. In the chemical composition of each microcalcification, the calcium hydroxyapatite has a phosphate substance, and calcium oxalate has an oxalate substance. The thicknesses of the calcium oxalate corresponding to calcium hydroxyapatite were calculated to preserve equal photon beam attenuation. The results indicate a higher mass ratio value in the case of malignant microcalcifications when compared with that in the case of benign ones. Even when the breast thickness increased up to 5 cm, the difference in the mass ratio exhibited a constant tendency. By excluding the effect on x-ray attenuation properties, we confirmed that malignant and benign microcalcifications were quantitatively distinguished based only on the mineral properties of the chemical composition. In conclusion, this study provides quantitative and objective indicators, a non-invasive discrimination method of two types of microcalcifications associated with pathology. We also expect to reduce the frequency of biopsies by improving the accuracy of early diagnosis in mammography.
The MERLINO project:characterization of LaBr3:Ce detectors for stopping power monitoring in proton therapy
Authors: Ferrero V. , Werner J. , Aglietta M. , Cerello P. , Fiorina E. , Gorgi A. , Vignati A. , Rafecas M. , Pennazio F. 
Published: November 2022

Abstract
The MERLINO project is developing a multi-detector setup with the goal of evaluating the beam stopping power from Prompt-Gamma-Timing measurements in proton therapy. The detectors are based on the cerium-doped lanthanum bromide crystal, LaBr3:Ce, coupled to photo-multiplier tubes. The system characterization is ongoing and the first calibration measurements with two detectors showed 124 ps σ and σ
E/E = 3% for the timing and energy resolution, respectively. The measured experimental parameters were then used to carry out a preliminary estimation of the stopping power. Results from the simulation of a 189 MeV proton beam impinging on an homogeneous phantom are presented for the optimisation of the MERLINO detector setup.
Impacts of climate change on global food trade networks
Authors: Hedlund Johanna , Carlsen Henrik , Croft Simon , West Chris , Bodin Örjan , Stokeld Emilie , Jägermeyr Jonas , Müller Christoph 
Published: November 2022

Abstract
Countries’ reliance on global food trade networks implies that regionally different climate change impacts on crop yields will be transmitted across borders. This redistribution constitutes a significant challenge for climate adaptation planning and may affect how countries engage in cooperative action. This paper investigates the long-term (2070–2099) potential impacts of climate change on global food trade networks of three key crops: wheat, rice and maize. We propose a simple network model to project how climate change impacts on crop yields may be translated into changes in trade. Combining trade and climate impact data, our analysis proceeds in three steps. First, we use network community detection to analyse how the concentration of global production in present-day trade communities may become disrupted with climate change impacts. Second, we study how countries may change their network position following climate change impacts. Third, we study the total climate-induced change in production plus import within trade communities. Results indicate that the stability of food trade network structures compared to today differs between crops, and that countries’ maize trade is least stable under climate change impacts. Results also project that threats to global food security may depend on production change in a few major global producers, and whether trade communities can balance production and import loss in some vulnerable countries. Overall, our model contributes a baseline analysis of cross-border climate impacts on food trade networks.
Tree rings reveal changes in the temperature pattern in eastern China before and during the Anthropocene
Authors: Sun Changfeng , Li Qiang , Liu Yu , Song Huiming , Fang Congxi , Cai Qiufang , Ren Meng , Ye Yuanda , Liu Ruoshi , Sun Junyan 
Published: November 2022

Abstract
A comprehensive understanding of the spatial characteristics of warming trends and temperature variability is important given global warming. Paleoclimate reconstruction has played an important role in evaluating warming and extreme climactic events in recent decades. Using the ring width of Pinus tabulaeformis, we reconstructed the ground surface temperature changes at Mengshan Mountain, in the central part of eastern China (EC), from 1667 to 2019. There were 3 extremely low-temperature years, 42 low-temperature years, 256 normal years, 37 high-temperature years and 15 extremely high-temperature years over the past 353 years. High and extremely high temperatures mainly occurred in the first half of the 19th century, the end of the 20th century and the beginning of the 21st century; low and extremely low temperatures occurred in almost all periods except for the last 50 years. By combining the past temperature reconstructions from the Great Xing’an Mountains in northern EC and Taiwan in southern EC, we also found that after the start of the Anthropocene, there were strong positive correlations among the temperatures of the northern, central and southern parts of EC. However, before the Anthropocene, these correlations were weak, and there was even a significant negative correlation during some periods. Additionally, the temperature in EC exhibited different change patterns before and during the Anthropocene. Before the Anthropocene, the temperature in southern EC showed an upward trend; in central EC, the temperature first rose and then began to decline in the 1820s; there was no obvious trend in the temperature changes in northern EC. The spatial consistency of temperature changes during the Anthropocene might be related to the fact that greenhouse gases emitted by human activities diffuse evenly withatmospheric circulation and absorb longwave radiation to directly heat the atmosphere.
Breast cancer detection using volatile compound profiles in exhaled breath via selected ion-flow tube mass spectrometry
Authors: Nakayama Yoshie , Hanada Mariko , Koda Hiroshi , Sugimoto Masahiro , Takada Masahiro , Toi Masakazu 
Published: November 2022

Abstract
This study aimed to evaluate volatile compounds in exhaled breath as a non-invasive screening method to detect breast neoplasms. Exhaled breath samples were collected from patients with breast cancer (BC; n = 45) and non-breast cancer (NBC; n = 51) controls. Selected ion-flow tube mass spectrometry was used to quantify the volatile compounds. A multiple logistic regression (MLR) model was developed by combining multiple compounds to discriminate between BC and NBC samples. Amongst the 672 quantified peaks, 17 showed significant differences between BC and NBC samples (P < 0.05 corrected by false discovery rate). Pathway analysis revealed a significant difference in glycerophospholipid metabolism. The MLR model showed an area under the receiver operating characteristic curve (AUC) of 0.719 (95% confidence interval: 0.615–0.822, P < 0.0002). Cross-validation under various conditions resulted in a slight fluctuation in the AUC values, indicating the high generalizability of the MLR model. The model showed a higher BC probability for advanced-stage subjects and higher Ki67 (⩾30) for BC subjects. This study suggests the potential of volatile compounds in exhaled breath as a noninvasive screening method for BC.
Pharmacologic venous thromboembolism prophylaxis in obese trauma patients
Authors: Erstad Brian L , Barletta Jeffrey F 
Published: November 2022

AbstractPurposeTo review the evidence cited in recent consensus documents providing recommendations for drug dosing for venous thromboembolism (VTE) prophylaxis in obese trauma patientsSummaryRecent publications from the American Association for the Surgery of Trauma and the American College of Surgeons provide recommendations for VTE prophylaxis in trauma. These documents address key aspects of pharmacologic prophylaxis, one of which is drug dosing in obesity. Both documents provide recommendations for obese patients, but they were not formulated using Grading of Recommendations Assessment, Development and Evaluation methodology, which has become the standard approach for guideline development. We reviewed and critiqued the literature cited in recently published consensus documents along with identifying additional studies retrieved from a PubMed search pertaining to drug dosing for VTE prophylaxis in obesity. The overall body of evidence was reviewed, and caveats for application in the clinical setting are provided. Dosing strategies for obese trauma patients are largely extrapolated from studies conducted in nonobese patients. Studies evaluating clinical outcomes are limited as most rely on anti–factor Xa concentrations versus VTE occurrence.ConclusionThe strength of the evidence surrounding dosing recommendations for VTE prophylaxis in obese trauma patients is low. Further research efforts should be directed towards this subset of trauma patients.
BacARscan: an in silico resource to discern diversity in antibiotic resistance genes
Authors: Pandey Deeksha , Kumari Bandana , Singhal Neelja , Kumar Manish 
Published: November 2022

Abstract
Antibiotic resistance has escalated as a significant problem of broad public health significance. Regular surveillance of antibiotic resistance genes (ARGs) in microbes and metagenomes from human, animal and environmental sources is vital to understanding ARGs’ epidemiology and foreseeing the emergence of new antibiotic resistance determinants. Whole-genome sequencing (WGS)-based identification of the microbial ARGs using antibiotic resistance databases and in silico prediction tools can significantly expedite the monitoring and characterization of ARGs in various niches. The major hindrance to the annotation of ARGs from WGS data is that most genome databases contain fragmented genes/genomes (due to incomplete assembly). Herein, we describe an insilicoBacterial Antibiotic Resistance scan (BacARscan) (http://proteininformatics.org/mkumar/bacarscan/) that can detect, predict and characterize ARGs in -omics datasets, including short sequencing, reads, and fragmented contigs. Benchmarking on an independent non-redundant dataset revealed that the performance of BacARscan was better than other existing methods, with nearly 92% Precision and 95% F-measure on a combined dataset of ARG and non-ARG proteins. One of the most notable improvements of BacARscan over other ARG annotation methods is its ability to work on genomes and short-reads sequence libraries with equal efficiency and without any requirement for assembly of short reads. Thus, BacARscan can help monitor the prevalence and diversity of ARGs in microbial populations and metagenomic samples from animal, human, and environmental settings. The authors intend to constantly update the current version of BacARscan as and when new ARGs are discovered. Executable versions, source codes, sequences used for development and usage instructions are available at (http://www.proteininformatics.org/mkumar/bacarscan/downloads.html) and GitHub repository (https://github.com/mkubiophysics/BacARscan).