bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mother's Sense of Coherence and Oral Health of Children and Adolescents With Cerebral Palsy—Matched Cross‐Sectional Study
Authors: Siqueira Vanessa Lira , Pacheco Valéria Bordallo , Gonçalves Laura Costa , Carneiro Natália Cristina Ruy , Borges‐Oliveira Ana Cristina , dos Santos Maria Teresa Botti Rodrigues 
Published: February 2025

ABSTRACTBackgroundThe sense of coherence (SOC) is important for the well‐being, especially mothers of children and adolescents with cerebral palsy (CP).ObjectiveThis study aimed to investigate the relationship between Mother's SOC and oral health status in children/adolescents with and without CP.Materials and MethodA paired cross‐sectional study was conducted with 102 children/adolescents with CP, 102 without CP, and their respective mothers. Participants were aged between 3 and 17 years, matched by sex and age. Antonovsky's SOC questionnaire (SOC‐13) was answered by mothers from both groups, characteristics and the oral status of the children were investigated. Clinical type of CP, Gross Motor Function (GMFCS), oral hygiene quality (OHI‐S), and dental caries experience (DMFT/dmft) were evaluated.ResultsThe CP condition of the children was significantly associated with Mother's SOC (P < 0.001). Mothers of children with CP had lower SOC scores (mean: 27.6 [±3.0]) than mothers of children without CP (mean: 30.2 [±7.7]). In the CP group, level IV, V of Gross Motor function was associated with lower mother's SOC scores (p = 0.001). In both groups, dental caries experience was associated with lower mother's SOC scores, CP group (p < 0.001), without CP group (p = 0.002). Regarding the individual characteristics, CP group presented with lower‐quality of oral hygiene (p < 0.001) and high prevalence of dental caries (p = 0.001). Regarding marital status, mothers of CP group were majority single, separated, or divorced (p < 0.001), and presented more difficulties in finding a dentist for their child (p < 0.001).ConclusionMother's SOC was statistically significantly associated with the presence of dental caries in children/adolescents with and without CP. Mothers of children/adolescents with CP presented with lower values of SOC.
Characterisation of the Novel HLA‐DPB1*04:02:27 Allele by Sequencing‐Based Typing
Authors: Cargou Marine , Elsermans Vincent , Top Isabelle , Ralazamahaleo Mamy , Visentin Jonathan 
Published: February 2025

ABSTRACTHLA‐DPB1*04:02:27 differs from HLA‐DPB1*04:02:01:01 by one nucleotide substitution in codon 193 in exon 4.
Cross‐Border Regional Innovation Systems and Climate Adaptation: A Tripoint Viticultural Analysis
Authors: Riekötter Nicklas 
Published: February 2025

AbstractThis paper investigates sustainability transformations in the tripoint viticultural sectors of Luxembourg, Germany and France, employing the framework of Cross‐Border Regional Innovation Systems (CBRIS). Through qualitative data from semi‐structured interviews and extensive on‐site observations, the paper examines how viticulturists perceive and respond to climate change impacts and linked socio‐economic crises across national borders. The findings reveal diverse adaptation strategies, with German vintners showing a higher propensity for innovation and sustainable practices compared to their French and Luxembourgish counterparts. The study identifies key socio‐economic implications, including increased resilience and self‐reliance among climate‐friendly farmers and sheds a broader perspective on growth trajectories and cross‐border collaborations. Besides fostering knowledge exchange and regional sustainability, barriers such as financial constraints and knowledge gaps are also discussed. This research underscores the potential of analysing borders as dynamic entities under the CBRIS framework, adding to understanding of sustainability and resilience development in the regional economy and viticulture.
Where Mathematical Symbols Come From
Authors: Schlimm Dirk 
Published: February 2025

AbstractThere is a sense in which the symbols used in mathematical expressions and formulas are arbitrary. After all, arithmetic would be no different if we would replace the symbols ‘’ or ‘8’ by different symbols. Nevertheless, the shape of many mathematical symbols is in fact well motivated in practice. In the case of symbols that were introduced a long time ago, the original motivations remain mostly inaccessible to us. Accordingly, motivations that are discussed in the literature are only ascribed retrospectively and should be considered as post‐hoc rationalizations. For more recent introductions of new symbols (e.g., in symbolic logic), however, we sometimes do have first‐hand accounts by the authors that inform us of the reasons behind their notational choices. In this paper, I present a systematic overview of possible motivations for the design of mathematical symbols, which include practical (such as ease of writing and reuse of previously used symbols) as well as cognitive aspects (such as indicating relations to other symbols or to their intended meanings).
Leakage pressures of partial and total lung lobectomies performed with thoracoabdominal staplers in cadaveric dogs
Authors: Huerta Yael , Culp William T. N. , Gianotti Giacomo , Gill Nimar , Stefanovski Darko , Griffin Maureen A. 
Published: February 2025

AbstractObjectiveTo compare leakage pressures of stapled partial and total lung lobectomies using thoracoabdominal (TA) staplers in canine cadaveric specimens.Study designEx vivo experimental study.Sample populationA total of 29 lung lobes from six canine cadavers.MethodsLower respiratory tracts were harvested from canine cadavers >15 kg. Lung lobes were randomized to groups: total lobectomy with a TA30‐V3 (TL‐30), partial lobectomy with two TA30‐V3 cartridges in a wedge configuration (PL‐30), and partial lobectomy with a TA60‐3.5 mm (PL‐60). The leakage pressure (pressure at which air bubbles were first seen from submerged tissue) was assessed, and groups were compared.ResultsAll nine PL‐30 and all nine PL‐60 sites leaked at median pressures of 10 cm H2O (range 10–15) and 18 cm H2O (range 10–20), respectively. Only 1/11 TL‐30 site leaked during testing at a pressure of 22 cm H2O. PL‐30 and PL‐60 sites were more likely to leak at 20 (OR: 437; 95% CI: 7.9–24 171; p = .003) and 30 (OR: 133; 95% CI: 4.8–3674.2; p = .003) cm H2O compared to TL‐30 sites, and the leakage pressure was greater for TL‐30 as compared to PL‐30 (marginal effect: −46.14; 95% CI: −55.9 to −36.38; p < .001) and PL‐60 (marginal effect: −41.2; 95% CI: −51.73 to −30.67; p < .001) sites. PL‐60 leakage pressures were greater than those of PL‐30 (marginal effect: 4.94; 95% CI: 1.43–8.44; p = .006).ConclusionIn canine cadaveric lung, total lobectomies with a TA30‐V3 were less likely to leak at physiological pressures than partial lobectomies with either TA30‐V3 or TA60‐3.5 mm staplers.Clinical significanceThese results suggest a greater potential risk for air leakage at physiologically relevant pressures following partial as compared to total lobectomies with the TA stapling devices and techniques used commonly in veterinary surgery.
Phylogenetic analysis of geometric morphometric data: A study case in Didelphidae
Authors: Saguir Sergio O. , Haidr Nadia S. , Flores David A. , Catalano Santiago A. 
Published: February 2025

AbstractThe analysis of Geometric Morphometric Data (GMD) in a phylogenetic context is a common practice in current evolutionary analyses. However, its use as evidence to recover phylogenetic relationships remains controversial. While simulation analyses have indicated theoretical limits for phylogenetic inference based on GMD, empirical analyses have shown mixed results and emphasized the importance of proper character sampling. In this study, we evaluated the phylogenetic performance of GMD in phylogenetic reconstruction using a newly generated dataset on the Didelphidae family. This dataset comprises the largest character sampling generated to date, including information from 10 different skeletal structures represented by 14 landmark configurations. Specifically, our objectives were: (i) to evaluate how different superimposition procedures and the inclusion of semilandmarks affect phylogenetic inferences, (ii) to compare the phylogenetic performance of GMD and traditional characters, and (iii) to compare the phylogenetic information of cranial and postcranial data. We found that trees obtained from GMD and traditional discrete characters exhibited similar levels of correspondence with a reference molecular tree. The inclusion of semilandmarks led to worsened results, regardless of the methodology used to place them, and we found no clear evidence for the superiority of any particular landmark superimposition approach. Our results align with previous analyses demonstrating that the inclusion of a higher number of skeletal structures improves results. We discuss these findings in the context of the ongoing debate about the utility of GMD to infer phylogenetic relationships.
A stable splitting for spaces of commuting elements in unitary groups
Authors: Adem Alejandro , Gómez José Manuel , Gritschacher Simon 
Published: February 2025

AbstractWe prove an analogue of Miller's stable splitting of the unitary group for spaces of commuting elements in . After inverting , the space splits stably as a wedge of Thom‐like spaces of bundles of commuting varieties over certain partial flag manifolds. Using Steenrod operations, we prove that our splitting does not hold integrally. Analogous decompositions for symplectic and orthogonal groups as well as homological results for the one‐point compactification of the commuting variety in a Lie algebra are also provided.
The role of cellular senescence in endothelial dysfunction and vascular remodelling in arteriovenous fistula maturation
Authors: González Ignacia , Maldonado‐Agurto Rodrigo 
Published: February 2025

AbstractHaemodialysis (HD) is often required for patients with end‐stage renal disease. Arteriovenous fistulas (AVFs), a surgical procedure connecting an artery to a vein, are the preferred vascular access for HD due to their durability and lower complication rates. The aim of AVFs is to promote vein remodelling to accommodate increased blood flow needed for dialysis. However, many AVFs fail to mature properly, making them unsuitable for dialysis. Successful maturation requires remodelling, resulting in an increased luminal diameter and thickened walls to support the increased blood flow. After AVF creation, haemodynamic changes due to increased blood flow on the venous side of the AVF initiate a cascade of events that, when successful, lead to the proper maturation of the AVF, making it suitable for cannulation. In this process, endothelial cells play a crucial role since they are in direct contact with the frictional forces exerted by the blood, known as shear stress. Patients requiring HD often have other conditions that increase the burden of senescent cells, such as ageing, diabetes and hypertension. These senescent cells are characterized by irreversible growth arrest and the secretion of pro‐inflammatory and pro‐thrombotic factors, collectively known as the senescence‐associated secretory phenotype (SASP). This accumulation can impair vascular function by promoting inflammation, reducing vasodilatation, and increasing thrombosis risk, thus hindering proper AVF maturation and function. This review explores the contribution of senescent endothelial cells to AVF maturation and explores potential therapeutic strategies to alleviate the effects of senescent cell accumulation, aiming to improve AVF maturation rates.
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A Novel Concept to Manufacture Nano/Microcellular Foam Structures
Authors: Farahani Saeed , Hahn Marlon , Dardaei Joghan Hamed , Tekkaya A. Erman 
Published: February 2025

Abstract
Multi-material and multi-structure design, particularly the combination of metal-polymer and solid-foam, stands as a promising strategy to reduce component weight while increasing and diversifying their functionalities. However, adopting such design approaches faces significant challenges, primarily arising from the complex multi-stage manufacturing processes, necessitating multiple sets of equipment, tooling, and precise control at each production stage. In response to these formidable manufacturing hurdles, this paper introduces an innovative approach that integrates injection molding, forming, and foaming processes into a single hybrid process called Electromagnetic Forming Injection Foaming (EFIF). In this integration concept, the challenges related to the shrinkage and viscosity of polymer melt are addressed by utilizing supercritical fluid (SCF) foaming technology. Moreover, the incorporation of electromagnetic forming offers precise control over the foaming process, potentially enabling the creation of micro- to nanocellular structures in the injected polymeric material. As the proposed integration is a manufacturing innovation, with no available information in the literature directly relating to this concept, this study explores the basic principles, feasibility and effectiveness of the proposed integration in two preliminary studies. In the first study, the effects of pressure drop and drop rate on the cell nucleation and the morphology of the final foam structure are discussed along with various methods of creating pressure drop and drop rate in both conventional and hybrid foam injection molding processes. In the following, the experimental setup and study conducted to determine the impact of pressure drop and drop rate on the cell size and cell density are described, and the results are discussed. The second study focuses on the potential effects of integrating electromagnetic forming with the injection, forming, and foaming processes. A set of experiments is designed and conducted to evaluate the effect of the polymer layer on the electromagnetic forming. The initial evaluation shows that different boundary conditions, in this case, the adhesion of the polymer to the blank, significantly affect the forming result, which highlights the need for more fundamental research. In conclusion, this paper underscores the substantial potential of the EFIF concept to merge multiple commercially available technologies to find a scalable solution for manufacturing micro- to nanocellular polymer foams, which can eventually unlock the socio-economic benefits associated with the production of high-performance, multi-functional components.
Traits determine dispersal and colonization abilities of microbes
Authors: Echenique-Subiabre Isidora , Jackrel Sara L. , McCarren Jay , James Chase C. , Perez-Coronel Elisabet , Tran Cindy , Perreault Madeline , Farah Ugbad , White P. Signe , Baker Henry K. , Wall Christopher B. , Sager Lindsay , Becker Scott , Barton Andrew D. , Shurin Jonathan B. 
Published: February 2025

ABSTRACT

Many microbes disperse through the air, yet the phenotypic traits that enhance or constrain aerial dispersal or allow successful colonization of new habitats are poorly understood. We used a metabarcoding bacterial and eukaryotic data set to explore the trait structures of the aquatic, terrestrial, and airborne microbial communities near the Salton Sea, California, as well as those colonizing a series of experimental aquatic mesocosms. We assigned taxonomic identities to amplicon sequence variants (ASVs) and matched them to functional trait values through published papers and databases that infer phenotypic and/or metabolic traits information from taxonomy. We asked what traits distinguish successful microbial dispersers and/or colonizers from terrestrial and aquatic source communities. Our study found broad differences in taxonomic and trait composition between dispersers and colonizers compared to the source soil and water communities. Dispersers were characterized by larger cell diameters, colony formation, and fermentation abilities, while colonizers tended to be phototrophs that form mucilage and have siliceous coverings. Shorter population doubling times, spore-, and/or cyst-forming organisms were more abundant among the dispersers and colonizers than the sources. These results show that the capacity for aerial dispersal and colonization varies among microbial functional groups and taxa and is related to traits that affect other functions like resource acquisition, predator avoidance, and reproduction. The ability to disperse and colonize new habitats may therefore distinguish microbial guilds based on tradeoffs among alternate ecological strategies.

IMPORTANCE
Microbes have long been thought to disperse rapidly across biogeographic barriers; however, whether dispersal or colonization vary among taxa or groups or is related to cellular traits remains unknown. We use a novel approach to understand how microorganisms disperse and establish themselves in different environments by looking at their traits (physiology, morphology, life history, and behavior characteristics). By collecting samples from habitats including water, soil, and the air and colonizing experimental tanks, we found dispersal and invasion vary among microorganisms. Some taxa and functional groups are found more often in the air or colonizing aquatic environments, while others that are commonly found in the soil or water rarely disperse or invade new habitat. Interestingly, the traits that help microorganisms survive and thrive also play a role in their ability to disperse and colonize. These findings have significant implications for understanding microorganisms’ success and adaptation to new environments.
Chlamydia trachomatis
: a model for intracellular bacterial parasitism
Authors: Smith Erin P. , Valdivia Raphael H. 
Published: February 2025

ABSTRACT

Chlamydia
comprises a diverse group of obligate intracellular bacteria that cause infections in animals, including humans. These organisms share fascinating biology, including distinct developmental stages, non-canonical cell surface structures, and adaptations to intracellular parasitism.
Chlamydia trachomatis
is of particular interest due to its significant clinical importance, causing both ocular and sexually transmitted infections. The strain L2/434/Bu, responsible for lymphogranuloma venereum, is the most common strain used to study chlamydial molecular and cell biology because it grows readily in cell culture and is amenable to genetic manipulation. Indeed, this strain has enabled researchers to tackle fundamental questions about the molecular mechanisms underlying
Chlamydia’s
developmental transitions and biphasic lifecycle and cellular adaptations to obligate intracellular parasitism, including characterizing numerous conserved virulence genes and defining immune responses. However, L2/434/Bu is not representative of
C. trachomatis
strains that cause urogenital infections in humans, limiting its utility in addressing questions of host tropism and immune evasion in reproductive organs. Recent research efforts are shifting toward understanding the unique attributes of more clinically relevant
C. trachomatis
genovars.
Carbon upshift in
Lactococcus cremoris
elicits immediate initiation of proteome-wide adaptation, coinciding with growth acceleration and pyruvate dissipation switching
Authors: van Olst Berdien , Boeren Sjef , Vervoort Jacques , Kleerebezem Michiel 
Published: February 2025

ABSTRACT

Fitness optimization in a dynamic environment requires bacteria to adapt their proteome in a tightly regulated manner by altering protein production and/or degradation. Here, we investigate proteome adaptation in
Lactococcus cremoris
following a sudden nutrient upshift (e.g., nutrients that allow faster growth) and focus especially on the fate of redundant proteins after the shift. Protein turnover analysis demonstrated that
L. cremoris
cultures shifted from galactose to glucose, immediately accelerate growth and initiate proteome-wide adjustment toward glucose-optimized composition. Redundant proteins were predominantly adjusted by lowering (or stopping) protein production combined with dilution by growth. However, pyruvate formate lyase activator (PflA) was actively degraded, which appears correlated to reduced 4Fe-4S cofactor availability. Active PflA removal induces the shutdown of galactose-associated mixed acid fermentation to accelerate the switch toward glucose-associated homolactic fermentation. Our work deciphers molecular adjustments upon environmental change that drive physiological adaptation, including growth rate and central energy metabolism.

IMPORTANCE

Bacteria adapt to their environment by adjusting their molecular makeup, in particular their proteome, which ensures fitness optimization under the newly encountered environmental condition. We present a detailed analysis of proteome adaptation kinetics in
Lactococcus cremoris
following its acute transition from galactose to glucose media, as an example of a sudden nutrient quality upshift. Analysis of the replacement times of individual proteins after the nutrient upshift established that the entire proteome is instantly adjusting to the new condition, which coincides with immediate growth rate acceleration and metabolic adaptation. The latter is driven by the active removal of the pyruvate formate lyase activator protein that is pivotal in controlling pyruvate dissipation in
L. cremoris
. Our work exemplifies the amazing rate of molecular adaptation in bacteria that underlies physiological adjustments, including growth rate and carbon metabolism. This mechanistic study contributes to our understanding of adaptation in
L. cremoris
during the dynamic conditions it encounters during (industrial) fermentation, even though environmental transitions in these processes are mostly more gradual than the acute shift studied here.
Complete genome sequence of the unique
Rhizobium johnstonii
strain NaPi
Authors: Kirichek Evgenii A. , Afonin Alexey M. , Kusakin Pyotr G. , Tsyganov Viktor E. 
Published: February 2025

ABSTRACT

In contrast to
Rhizobium johnstonii
strain 3841,
R. johnstonii
strain NaPi is able to form large pink nodules on the roots of pea (
Pisum sativum
L.) mutants in the gene
Sym40
. The genetic determinants underlying such efficiency have not been discovered yet. In this study, we report the complete genome sequence of the strain NaPi.