bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sistem Pakar Mendiagnosis Penyakit Tanaman Cabai Merah Menggunakan Metode CBR
Authors: Karim Farhan , Drajana Ivo Colanus Rally 
Published: June 2022

Abstrak - Tanaman cabai merah merupakan jenis buah dan tumbuhan dalam anggota genus Capsicum yang masuk dalam komodias sayuran yang banyak dinikmati masyarakat Indonesia. Kabupaten Pohuwato merupakan salah satu wilayah yang menjadi sasaran utama dalam pengembangan tanaman holtikultura. Akan tetapi dalam pengembangannya komoditi ini memiliki beberapa permasalahan salah satunya Hama dan penyakit. Kendala utama dalam mendiagnosa penyakit cabai merah yaitu minimnya pengetahuan petani tentang penyakit tanaman cabai merah, keterbatasan waktu yang dimiliki petani, dan kurangnya jumlah pakar. Dalam mengatasi situasi ini, sistem pakar sangat dibutuhkan. Sistem pakar merupakan program berbasis pengetahuan, dengan sistem pakar dapat dengan mudah mendiagnosa penyakit yang menyerang cabai merah. Penelitian ini menerapkan metode Case Based Reasoning. Metode CBR merupakan metode yang membangun sistem dengan pengambilan keputusan dari kasus baru berdasarkan solusi dari kasus sebelumnya, menyelesaikan kasus baru dengan mengamati kasus lama yang terdekat dengan kasus baru. Sistem ini di bangun dengan 5 penyakit dengan 16 gejala yang memiliki bobot yang berbeda berdasarkan hasil penelitian. Dalam menguji kelayakan sistem dan menghindari kesalahan pada sistem, maka pada penelitian ini telah melakukan pengujian sistem dengan hasil pengujian sistem white box yang dilakukan menghasilkan nilai Cyclomatic Complexity 8, untuk pengujian sistem black box semuanya sesuai dengan tampilan pada sistem.Kata kunci: Sistem Pakar, Cabai Merah, CBR Abstract - The red chili plant is a type of fruit and plant in the genus Capsicum which is included in the vegetable commodity that is widely enjoyed by the people of Indonesia. Pohuwato Regency is one of the areas that are the main targets in the development of horticultural crops. However, in its development this commodity has several problems, one of which is pests and diseases. The main obstacle in diagnosing red chili disease is the lack of knowledge of farmers about red chili disease, the limited time farmers have, and the lack of experts. To overcome this, an expert system is needed. The expert system is a knowledge-based program, with the expert system being able to easily diagnose diseases that attack red chilies. This research uses Case Based Reasoning method. The CBR method is a method that builds a system by making decisions from new cases based on solutions from previous cases, solving new cases by observing the old cases that are closest to the new cases. This system is built with 5 diseases with 16 symptoms that have different weights based on the results of the study. In testing the feasibility of the system and avoiding errors in the system, this research has tested the system with the results of a white box system test that produces a value of Cyclomatic Complexity 8, for testing the black box system everything is in accordance with the appearance on the system.Keywords: Expert System, Red Chili, CBR
Sistem Pendukung Keputusan Seleksi Awal Penerima Kartu Indonesia Sehat (KIS) Menggunakan Metode ARAS
Authors: Betrisandi Betrisandi , Bahrin Bahrin 
Published: June 2022

Abstrak - Kartu Indonesia Sehat adalah kartu identitas peserta Jaminan Kesehatan Nasional yang dikelola oleh Badan Penyelenggara Jaminan Sosial Kesehatan. Saat ini program pemerintah bantuan KIS belum optimal dilaksanakan, hal ini dikarenakan penyaluran bantuan KIS belum mengacu pada kriteria yang ada. Tujuan dari penelitian ini yaitu membantu dalam pengambilan keputusan untuk menyeleksi awal penerima bantuan Kartu Indonesia Sehat (KIS) dengan menggunakan metode ARAS. Adapun hasil dari penelitian ini dibuktikan dengan pengujian yang gunakan yaitu white box dengan hasil V(G) = 5 didapat bahwa logika flowchart perhitungan normalisasi dan perangkingan benar dan pengujian black box meliputi uji input dan output dengan mengacu pada rancangan perangkat lunak telah terpenuhi dengan hasil sesuai dengan rancangan. Kata kunci: Sistem Pendukung Keputusan, KIS, ARAS Abstract - Healthy Indonesia Card is the identity card of the National Health Insurance participant managed by the Health Social Security Administering Body. Currently the government's KIS assistance program has not been optimally implemented, this is because the distribution of KIS assistance has not referred to the existing criteria. The purpose of this study is to assist in making decisions to select the recipients of the Healthy Indonesia Card (KIS) assistance using the ARAS method. The results of this study are evidenced by the testing used, namely white box with the results of V(G) = 5, it is found that the logic flowchart calculation of normalization and ranking is correct and black box testing includes input and output tests with reference to the software design has been met with the appropriate results. by design.Keywords: Decision Support System, KIS, ARAS
Prediksi Status Penderita Stunting Pada Balita Provinsi Gorontalo Menggunakan K-Nearest Neighbor Berbasis Seleksi Fitur Chi Square
Authors: Drajana Ivo Colanus Rally , Bode Andi 
Published: June 2022

Abstrak - Stunting adalah malnutrisi yang ditandai dengan tinggi badan, diukur dengan standar deviasi dari WHO. Dinas Kesehatan Provinsi Gorontalo khususnya dibidang Gizi mengenai stunting, selama ini melakukan kegiatan pemantauan tiap-tiap puskesmas dan posyandu. Pemantauan dan pendataan terkait stunting di berbagai puskesmas faktor penting. Masalah yang sering muncul adalah data yang dikumpulkan untuk underestimasi selalu tidak akurat setiap bulannya, karena hanya perkiraan yang dihitung berdasarkan kasus puskesmas. Prediksi yang akurat diperlukan untuk mengatasi permasalahan yang ada. Penelitian ini menggunakan algoritma K-Nearest Neighbor (K-NN) menggunkan Chi Square. Berdasarkan hasil eksperimen, prediksi jumlah penderita stunting telah berhasil dilakukan. Maka nilai hasil dari prediksi tersebut dapat diimplementasikan untuk bahan pertimbangan atau kebijakan didalam pengambilan keputusan. Tingkat error terkecil hasil RMSE 1,200 pada algoritma K-Nearest Neighbor menggunkan Chi Square dibandingkan algoritma K-Nesrest Neighbor tanpa seleksi fitur. Dengan demikian dari hasil eksperimen menunjukan bahwa penambahan seleksi fitur telah menunjukan performa kinerja yang baik pada algoritma K-Nearest Neighbor.Kata kunci: Prediksi, Stunting, K-NN, Chi Square Abstract - Stunting is a nutritional deficiency characterized by height as measured by the WHO standard deviation. The Gorontalo Provincial Health Office, especially in the field of nutrition related to stunting, has so far carried out monitoring activities at every puskesmas and posyandu. Monitoring and data collection related to stunting in various health centers is an important factor. The problem that often arises is that the data collected for underestimation is always inaccurate every month, because only estimates are calculated based on puskesmas cases. Accurate predictions are needed to overcome the existing problems. This study uses the K-Nearest Neighbor (K-NN) algorithm using Chi Square. Based on the experimental results, the prediction of the number of stunting sufferers has been successfully carried out. Then the value of the predicted results can be implemented for consideration or policy in decision making. The smallest error rate is RMSE 1,200 in the K-Nearest Neighbor algorithm using Chi Square compared to the K-Nesrest Neighbor algorithm without feature selection. Thus, the experimental results show that the addition of feature selection has shown good performance on the K-Nearest Neighbor algorithm.Keyword: Prediction, Stunting, K-NN, Chi Square
PENGARUH MANAJEMEN LABA DAN AGRESIVITAS PAJAK TERHADAP NILAI PERUSAHAAN PADA PERUSAHAAN SEKTOR OTOMOTIF DAN KOMPONEN DI BEI TAHUN 2016 - 2020
Authors: Sodikin Mohammad , Dewi Lutviana 
Published: June 2022

Tujuan dalam penelitian ini adalah untuk menganalisis pengaruh Manajemen Laba, Agresivitas Pajak terhadap Nilai Perusahaan Pada Perusahaan Sektor Otomotif dan Komponen di BEI Tahun 2016-2020. Pendekatan dalam studi ini menggunakan pendekatan kuantitatif. Dengan menggunakan teknik purposive sampling didapatkan sampel sebanyak 5 perusahaan. Teknik analisis data yang digunakan adalah analisis regresi linier berganda.
Berdasarkan hasil analisis dan pembahasan, maka dapat disimpulkan bahwa, Variabel manajemen laba berpengaruh signifikan terhadap nilai perusahaan pada perusahaan otomotif dan komponen di Bursa Efek Indonesia Tahun 2016-2020 dengan arah yang positif dan Variabel agresivitas pajak berpengaruh signifikan terhadap nilai perusahaan pada perusahaan otomotif dan komponen di Bursa Efek Indonesia Tahun 2016-2020 dengan arah pengaruh yang negatif
Fatores associados à violência escolar com adolescentes: uma revisão integrativa
Authors: Farias Ariany Cristine do Nascimento , Barros Mariana Boulitreau Siqueira Campos , Araújo Wallacy Jhon Silva , Silva Ana Claudia Cavalcante da , Oliveira Sevy Reis Dias Egydio de , Santos Tamyris Arcoverde , Sarmento Letícia Maria de Melo , Monteiro Estela Maria Leite Meirelles 
Published: June 2022

Uma vez que violência escolar é definida como um fenômeno multicausal, que envolve fatores sociais, econômicos, culturais, geográficos e históricos, objetivou-se nesse estudo verificar as evidências disponíveis na literatura sobre os fatores associados à violência escolar envolvendo adolescentes. Para a síntese do conhecimento foi empregada a revisão integrativa da literatura, nas bases de dados da Literatura Latino-Americana e do Caribe em Ciências da Saúde (Lilacs), Medical Literature Analysis and Retrieval System Online (Medline/PUBMED), Web of Science e Scopus, onde foi totalizado 21 artigos no recorte temporal de 2014 a 2018 e submetidos à análise a partir de categorias temáticas. Emergiram oito categorias associadas à violência escolar/bullying: 1) o perfil sóciodemográfico dos envolvidos na violência escolar, 2) a influência das relações interpessoais, 3) os sentimentos com a escola e o corpo escolar, 4) as formas da violência perpetrada, 5) os fatores protetivos para violência escolar, 6) os fatores de risco para violência escolar, 7) as principais causas da vitimização e 8) as consequências reais do cyberbullying. Adolescentes que crescem e se desenvolvem em ambientes de extrema desigualdade social e vulnerabilidades, com exposição a situações de violência, tendem a apreenderem uma concepção de normalização da violência, de modo a reproduzir esse comportamento diante de situações de conflito, evidenciando que não somente fatores intrínsecos à escola estariam diretamente ligados, como também uma inter-relação com situações de violência instituídas no contexto familiar e /ou comunitários. Como principais medidas protetivas destaca-se a promoção da autoestima, da autonomia e do empoderamento do adolescente.
PERANCANGAN SISTEM INFORMASI POSYANDU LANSIA RW 02 KAMPUNG JEMBATAN PENGGILINGAN JAKARTA TIMUR
Authors: Aji Pradibto , Suharyanto Suharyanto , Anton Anton 
Published: June 2022

Pemerintah sebagai penyediaan layanan pada masyarakat mengeluarkan program-program yang dilakukan dari level pusat, provinsi, kota, kecamatan hingga level kelurahan. Banyak orang tidak tahu berapa berat badan idealnya dan masyarakat tidak mengetahui berat badan pada bayi, balita, remaja, dewasa, dan lansia. Secara umum masyarakat kesulitan dalam memahami status gizi anaknya, hal ini tentu dapat menimbulkan masalah dalam mengontrol asupan gizi terhadap pertumbuhan anak. Karena pemahaman masyarakat mengenai status gizi anak masih tergolong cukup rendah dan bergantung pada pengetahuan serta kontrol gizi yang dilakukan oleh posyandu. Menyatakan akan pentingnya peran masyarakat dalam membangun kesehatan, maka Departemen Kesehatan menetapkan visi : “Masyarakat mandiri untuk hidup sehat”. Yaitu suatu kondisi dimana masyarakat Indonesia menyadari, mau dan mampu mengenali, mencegah dan mengatasi permasalahan kesehatan dihadapi, sehingga dapat bebas dari gangguan kesehatan yang dihadapi, maupun lingkungan yang tidak mendukung. Sistem Informasi Pelayanan Imunisasi di Posyandu nantinya diharapkan dapat mempermudah dalam pengelolahan data secara cepat dan tepat sasaran, sebagai dasar pengembangan integrasi layanan-layanan di masa depan terutama di dalam bidang posyandu yang lebih berpengaruh kepada pekembangan balita di suatu Rukun Warga. Tidak dipungkiri bahwa saat ini seluruh elemen masyarakat dapat dikatakan bergantung pada teknologi informasi.
ANALYSIS OF STUDENTS ERROR IN CLASS VIII A MTs DARUL HIKMAH IN SOLVING PROBLEMS ON THE RELATION AND FUNCTIONS MATERIALS
Authors: Nurwahyuni Sisi , Marnis Eli 
Published: June 2022

This research aims to know the students' mistakes on MTs Darul Hikmah Pekanbaru in solving questions relations and functions materials. This research was conduted in MTs Darul Hikmah Pekanbaru in the odd semester of Academic Year 2020/2021. This research uses a descriptive method with research form is a case study. Subjects in the study were four students. The analysis was made with the interview and discussion. Based on the results of research, it can be concluded that’s is types of student errors are in facts, concepts, and procedures.
STUDENTS’ MATHEMATICAL CONNECTION ABILITY IN TERMS OF SELF-CONFIDENCE
Authors: Risdayati Anisa Hilmia , Nurdin Erdawati , Kurniati Annisah 
Published: June 2022

The connection was needed to solve mathematics problems. In connecting some concepts existing in mathematics to other fields of science, student self-confidence was required to solve the encountered problems. It was qualitative research, and this research aimed at knowing and describing students’ mathematical connection ability derived from their self-confidence in quadrilateral and triangle materials. The subjects of this research were the seventh-grade students at Junior High School of Juara Pekanbaru. The purposive sampling technique was used in this research. The instruments used in this research were the self-confidence questionnaire, mathematical connection ability test question, and interview guideline. All data were analyzed in three steps—data reduction, data display, and concluding. The research findings and data analyses showed that students’ self-confidence at Junior High School of Juara Pekanbaru differed. Overall, student mathematical connection ability was in enough category with 71.7%. Students with high self-confidence owned very good mathematical connection ability category, students with moderate self-confidence owned enough mathematical connection ability category, and students with low self-confidence owned very poor mathematical connection ability category.
Heparanase 1 Upregulation Promotes Tumor Progression and Is a Predictor of Low Survival for Oral Cancer
Authors: Rodrigues André A. Nimtz , Lopes-Santos Lucilene , Lacerda Pammela A. , Juste Mariana F. , Mariz Bruno Augusto , Cajazeiro Débora C. , Giacobbe Victoria , Borges Rafael , Casarim André , Callegari Giovanna De Sanctis , Claret Arcadipane Fernando Antônio M. , Aprahamian Ivan , Salo Tuula Anneli , De Oliveira Carine Ervolino , Coletta Ricardo D. , Augusto Taize M. , Cervigne Nilva K. 
Published: June 2022

Background: Oral cavity cancer is still an important public health problem throughout the world. Oral squamous cell carcinomas (OSCCs) can be quite aggressive and metastatic, with a low survival rate and poor prognosis. However, this is usually related to the clinical stage and histological grade, and molecular prognostic markers for clinical practice are yet to be defined. Heparanase (HPSE1) is an endoglycosidase associated with extracellular matrix remodeling, and although involved in several malignancies, the clinical implications of HPSE1 expression in OSCCs are still unknown.Methods: We sought to investigate HPSE1 expression in a series of primary OSCCs and further explore whether its overexpression plays a relevant role in OSCC tumorigenesis. mRNA and protein expression analyses were performed in OSCC tissue samples and cell lines. A loss-of-function strategy using shRNA and a gain-of-function strategy using an ORF vector targeting HPSE1 were employed to investigate the endogenous modulation of HPSE1 and its effects on proliferation, apoptosis, adhesion, epithelial–mesenchymal transition (EMT), angiogenesis, migration, and invasion of oral cancer in vitro.Results: We demonstrated that HPSE1 is frequently upregulated in OSCC samples and cell lines and is an unfavorable prognostic indicator of disease-specific survival when combined with advanced pT stages. Moreover, abrogation of HPSE1 in OSCC cells significantly promoted apoptosis and inhibited proliferation, migration, invasion, and epithelial–mesenchymal transition by significantly decreasing the expression of N-cadherin and vimentin. Furthermore, a conditioned medium of HPSE1-downregulated cells resulted in reduced vascular endothelial growth.Conclusion: Our results confirm the overexpression of HPSE1 in OSCCs, suggest that HPSE1 expression correlates with disease progression as it is associated with several important biological processes for oral tumorigenesis, and can be managed as a prognostic marker for patients with OSCC.
Conserved Amino Acids Residing Outside the Voltage Field Can Shift the Voltage Sensitivity and Increase the Signal Speed and Size of Ciona Based GEVIs
Authors: Sepehri Rad Masoud , Cohen Lawrence B. , Baker Bradley J. 
Published: June 2022

To identify potential regions of the voltage-sensing domain that could shift the voltage sensitivity of Ciona intestinalis based Genetically Encoded Voltage Indicators (GEVIs), we aligned the amino acid sequences of voltage-gated sodium channels from different organisms. Conserved polar residues were identified at multiple transmembrane/loop junctions in the voltage sensing domain. Similar conservation of polar amino acids was found in the voltage-sensing domain of the voltage-sensing phosphatase gene family. These conserved residues were mutated to nonpolar or oppositely charged amino acids in a GEVI that utilizes the voltage sensing domain of the voltage sensing phosphatase from Ciona fused to the fluorescent protein, super ecliptic pHluorin (A227D). Different mutations shifted the voltage sensitivity to more positive or more negative membrane potentials. Double mutants were then created by selecting constructs that shifted the optical signal to a more physiologically relevant voltage range. Introduction of these mutations into previously developed GEVIs resulted in Plos6-v2 which improved the dynamic range to 40% ΔF/F/100 mV, a 25% increase over the parent, ArcLight. The onset time constant of Plos6-v2 is also 50% faster than ArcLight. Thus, Plos6-v2 appears to be the GEVI of choice.
Ultra-Tough Polylactide/Bromobutyl Rubber-Based Ionomer Blends via Reactive Blending Strategy
Authors: Zhang Xingfang , Lu Xu , Huang Dong , Ding Yingli , Li Jinshan , Dai Zhenyu , Sun Liming , Li Jin , Wei Xiaohui , Wei Jie , Li Yang , Zhang Kunyu 
Published: June 2022

A series of ultra-toughened sustainable blends were prepared from poly(lactic acid) (PLA) and bromobutyl rubber-based ionomers (i-BIIRs) via reactive blending, in which dicumyl peroxide (DCP) and Joncryl®ADR-4440 (ADR) were used as reactive blending additives. The miscibility, phase morphology and mechanical property of the PLA/i-BIIRs blends were thoroughly investigated through DMA, SEM, tensile and impact tests. The influence of different ionic groups and the effects of DCP and ADR on the compatibility between the phases, phase structure and mechanical properties were analyzed. The introduction of the imidazolium-based ionic groups and the reactive agents enable the i-BIIRs play multiple roles as effective compatibilizers and toughening agents, leading to improved interfacial compatibility and high toughness of the blends. The mechanical properties test showed that the PLA/i-BIIRs blends exhibit excellent toughness: impact strength and the elongation at break of AR-OH(30)+AD reached 95 kJ/m2 and 286%, respectively. The impact fracture surface showed the large-scale plastic deformation of the PLA matrix in the blends, resulting in greatly absorbing the impact energy. The results proved that simultaneously applying reactive blend and multiple intermolecular interactions methods is an effective toughening strategy for toughening modification of the PLA blends.
Gut Microbiota Protected Against pseudomonas aeruginosa Pneumonia via Restoring Treg/Th17 Balance and Metabolism
Authors: Wen Long , Shi Lei , Kong Xiang-Long , Li Ke-Yu , Li Hui , Jiang Di-Xuan , Zhang Fan , Zhou Zhi-Guo 
Published: June 2022

Backgrounds and PurposeThe theory of “entero-pulmonary axis” proves that pneumonia leads to gut microbiota disturbance and Treg/Th17 immune imbalance. This study is aimed to explore the potential mechanism of fecal microbiota transplantation (FMT) in the treatment of Pseudomonas aeruginosa pneumonia, in order to provide new insights into the treatment of pneumonia.MethodsPseudomonas aeruginosa and C57/BL6 mice were used to construct the acute pneumonia mouse model, and FMT was treated. Histopathological changes in lung and spleen were observed by HE staining. The expression of CD25, Foxp3 and IL-17 was observed by immunofluorescence. The proportion of Treg and Th17 cells was analyzed by flow cytometry. Serum IL-6, LPS, and IFN-γ levels were detected by ELISA. The expression of TNF-α, IFN-γ, IL-6, IL-2, Foxp3, IL-17, IL-10, and TGFβ1 in lung tissue homogenate was detected by qRT-PCR. 16S rRNA sequencing and non-targeted metabolomics were used to analyze gut microbiota and metabolism.ResultsPseudomonas aeruginosa caused the decrease of body weight, food and water intake, lung tissue, and spleen injury in mice with pneumonia. Meanwhile, it caused lung tissue and serum inflammation, and Treg/Th17 cell imbalance in mice with pneumonia. Pseudomonas aeruginosa reduced the diversity and number of gut microbiota in pneumonia mice, resulting in metabolic disorders, superpathway of quinolone and alkylquinolone biosynthesis. It also led to the decrease of 2-heptyl-3-hydroxy-4(1H)-quinolone biosynthesis, and the enrichment of Amino sugar and nucleotide sugar metabolism. FMT with or without antibiotic intervention restored gut microbiota abundance and diversity, suppressed inflammation and tissue damage, and promoted an immunological balance of Treg/Th17 cells in mice with pneumonia. In addition, FMT inhibited the aerobactin biosynthesis, 4-hydroxyphenylacetate degradation, superpathway of lipopolysaccharide biosynthesis and L-arabinose degradation IV function of microbiota, and improved amino sugar and nucleotide sugar metabolism.ConclusionsFMT restored the Treg/Th17 cells’ balance and improved inflammation and lung injury in mice with Pseudomonas aeruginosa pneumonia by regulating gut microbiota disturbance and metabolic disorder.