bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Pengaruh Pertumbuhan Arus Kas dan Profitabilitas Terhadap Return Saham pada Perusahaan LQ 45 di Bursa Efek Indonesia
Authors: Ginting Suriani 
Published: September 2022

Pasar modal memiliki fungsi keuangan, karena pasar modal memberikan kemungkinan dan kesempatan memperoleh imbalan (return) bagi pemilik dana. Tujuan penelitian ini adalah untuk menganalisis pengaruh pertumbuhan arus kas??? (arus kas operasi, arus kas investasi, arus kas pendanaan) dan Profitabilitas (Return on Asset, Return on Equity, Net Profit Margin) terhadap return saham perusahaan LQ 45 di Bursa Efek Indonesia baik secara simultan maupun secara parsialPopulasi dalam penelitian ini sebanyak 45 perusahaan. merupakan perusahaaan yang termasuk dalam LQ 45 yang terdaftar di Bursa Efek Indonesia pada periode Agustus 2010. Sampel dalam penelitian ini sebanyak 20 perusahaan yang konsisten masuk pemeringkatan LQ 45 sejak Agustus 2005 ?¢â?¬â?? Agustus 2010. Tehnik sampel dilakukan dengan purposive sampling. Analisis data menggunakan analisis regresi linear berganda. Hasil penelitian ini menunjukkan behwa secara simultan seluruh variabel independen berpengaruh signifikan terhadap return saham. Secara parsial variabel arus kas operasi dan Return on Asset berpengaruh signifikan terhadap return saham Sedangkan variabel arus kas investasi, arus kas pendanaan, Return on Equity, Net Profit Margin tidak berpengaruh terhadap return saham. Hal ini menunjukkan bahwa, variabel arus kas investasi, arus kas pendanaan kurang menjadi perhatian para investor. Dari hasil penelitian menunjukkan bahwa pada periode pengamatan, variabel Return on Asset yang merupakan informasi yang menghubungkan antara laporan laba - rugi dan neraca berpengaruh tergadap return saham ???
Ensino de Enfermagem
Authors: Amendoeira José 
Published: September 2022

O Ensino de enfermagem vive na actualidade um dos períodos do seu processo evolutivo onde o debate se impõe de forma profunda, mobilizando os actores, os contextos e os saberes ao longo das diferentes épocas numa abordagem que é suportada em dois pressupostos organizadores:
1 - Um, em que reflectimos numa perspectiva sócio-histórica sobre a evolução da educação em enfermagem em Portugal, por referência à segunda metade do século XX e início do século XXI, reportando-nos essencialmente a um conjunto de factos que caracterizam a década de 90 e o início do século XXI.
2 - Outro, em que consideramos de forma integrada, este período como um espaço transicional de análise, que nos permite reflectir sobre se, na actualidade o ensino de enfermagem vive uma mudança de paradigma ou se estamos perante um paradigma em transição. Posicionamo-nos manifestamente na segunda perspectiva.
Recorremos ao modelo transicional, como metodologia de análise sócio-histórica do fenómeno.
Finalizaremos partilhando alguns aspectos para reflexão, no âmbito das perspectivas de desenvolvimento do ensino de enfermagem, mobilizando para o efeito os constrangimentos advenientes essencialmente das incertezas com que o presente e o futuro se nos apresenta.

* Artigo baseado na conferência proferida no dia 5 de Dezembro de 2008, no âmbito das Comemorações do dia da Escola Superior de Enfermagem de Lisboa.
Gestão do estado emocional da criança (dos 6 aos 8 anos) através da actividade de brincar
Authors: Pereira Ana Margarida , Nunes Joana , Teixeira Séfora , Diogo Paula 
Published: September 2022

O presente estudo, de abordagem qualitativa, visa compreender como o brincar integrado na prática de enfermagem pode ser usado na gestão do estado emocional da criança a viver uma experiência de hospitalização/cirurgia. Neste processo investigativo recorreu-se ao diário de campo para descrever e analisar a própria prática de enfermagem associada ao fenómeno em estudo. A recolha dos dados foi realizada num serviço de internamento de pediatria cirúrgica de um hospital pediátrico de Lisboa, no período de Abril a Junho de 2008, a partir de interacções de cuidados com 9 crianças de idades compreendidas entre os 6 e os 8 anos. Os dados foram analisados segundo a técnica de análise de conteúdo, os quais revelaram um processo de gestão do estado emocional da criança, através da actividade de brincar, que implica as seguintes acções/interacções: promover o confronto adaptativo, favorecer o relaxamento, incrementar o sentimento de controlo, promover o sentimento de segurança, facilitar a aproximação, promover a expressão emocional, minimizar o sentimento de solidão, promover a distracção e desmistificar os medos. Conclui-se que a actividade de brincar é um instrumento terapêutico primordial em enfermagem pediátrica, na medida em que se revela um meio para favorecer o bem-estar das crianças, e por isso é sugestivo de contribuir para resultados terapêuticos. De facto, usado de modo intencional e sistemático promove a adaptação e aprendizagem das crianças numa experiência positiva de hospitalização/cirurgia.

* Monografia de final de Curso apresentada à Escola Superior de Enfermagem de Lisboa, Pólo Maria Fernanda Resende, no âmbito do 6º Curso de Licenciatura em Enfermagem, 2008.
The association between narcolepsy during pregnancy and maternal-fetal risk factors/outcomes
Authors: Wilson Annise , Dongarwar Deepa , Carter Krystal , Marroquin Maricarmen , Salihu Hamisu M 
Published: September 2022

Objective We sought to determine whether narcolepsy in pregnancy is associated with adverse maternal-fetal outcomes.
Material and Methods A retrospective, cross-sectional analysis was performed using the nationwide inpatient sample (NIS) for the period 2008-2017. The primary exposure was narcolepsy with cataplexy, narcolepsy type 1 (NT1), and without cataplexy, narcolepsy type 2 (NT2), and the endpoints were a composite of maternal-fetal outcomes or risk factors.
Results A total of 7,742 hospitalizations among pregnant women with narcolepsy were identified (prevalence = 17.6 per 100,000), of which 6,769 (88%) were diagnosed with NT2. Statistically significant positive associations were found between narcolepsy and the following conditions: obesity (odds ratio (OR): 2.99, confidence interval (CI): 2.4-3.74), anemia (OR=1.41, CI: 1.13-1.77), pre-pregnancy hypertension (OR=1.93, CI: 1.37-2.7), pre-pregnancy diabetes (OR=1.7, CI: 1.08-2.84), and gestational hypertension (OR=1.58, CI: 1.13-2.20) in the ICD-9 group. Similar findings were noted in the ICD-10 group with the exception of gestational hypertension, gestational diabetes, and anemia.
Conclusion Given these important findings, we propose a global approach of screening for narcolepsy among women of reproductive age with pre-existing risk factors prior to conception to minimize pregnancy complications.
Asylum seeker trauma in a student-run clinic: reducing barriers to forensic medical evaluations
Authors: Gallagher Aaron , Steiner Gabriela , Michel Martha , Gonzales Cesar Nava , Mendez-Contreras Sabrina , Lu Alice , Armendariz Marcos , DeFries Triveni , Barakat Suzanne , Kivlahan Coleen 
Published: September 2022

Introduction: The number of forcibly displaced immigrants entering the United States continues to rapidly increase. Movement from Latin America across the southern border of the United States was the third-largest migration worldwide in 2017; the U.S. now serves as home to one-fifth of the world’s migrants (Budiman, 2020; Leyva-Flores et al., 2019). Reporting on the first two years of clients receiving forensic medical evaluations (FMEs) conducted by clinicians trained at University of California, San Francisco (UCSF), this descriptive study demonstrates the multiple layers and types of trauma in asylum seekers presenting to a student-run asylum clinic (SRAC) at an academic medical center.

Methods: A retrospective review of the first 102 asylum seekers presenting to a university-affiliated SRAC for forensic medical and psychological evaluations is summarized. Demographics, immigration history, medical and mental health histories, descriptions of extensive trauma and referral patterns are reported. Multivariate statistics were employed to investigate the relationship between past trauma and current mental health status.

Results: Clients reported extensive trauma histories, with an average of 4.4 different types of ill-treatment per person, including physical, psychological, and sexual violence. The current mental health burden was extensive with 86.9 percent of clients reporting symptoms of PTSD and/or depression. Clients were evaluated within a clinic structure that intentionally aligns with SAMHSA’s implementation domains of trauma-informed care using a continuous improvement model to reduce barriers to FMEs and promote longitudinal follow-up and referral access.

Discussion: This study demonstrates the profound trauma exposure reported by asylum seekers, as well as the adaptation of a SRAC to better respond to complex trauma through intentional structural and leadership decisions. The HRC experience provides a blueprint for other asylum clinics to implement systematic trauma-centered services.
Comparison of Management and Outcomes in ERBB2-Low vs ERBB2-Zero Metastatic Breast Cancer in France
Authors: de Calbiac Ombline , Lusque Amélie , Mailliez Audrey , Bachelot Thomas , Uwer Lionel , Mouret-Reynier Marie-Ange , Emile George , Jouannaud Christelle , Gonçalves Anthony , Patsouris Anne , Diéras Véronique , Leheurteur Marianne , Petit Thierry , Cottu Paul , Ferrero Jean-Marc , D'Hondt Véronique , Desmoulins Isabelle , Mourato-Ribeiro Joana , Martin Anne-Laure , Frenel Jean-Sébastien 
Published: September 2022

ImportanceERBB2-low (ie, ERBB2 immunohistochemistry score of 1+ or 2+ in the absence of ERBB2 gene amplification) breast cancer (BC) is a new entity, with emerging dedicated treatments. Little is known about its prognosis and response to conventional therapy compared with ERBB2-zero breast tumors (ie, those with an immunohistochemistry score of 0).ObjectiveTo compare the outcomes for patients with ERBB2-low metastatic BC (MBC) with those of patients with ERBB2-zero MBC.Design, Setting, and ParticipantsThis cohort study was conducted from the Epidemiological Strategy and Medical Economics MBC platform and included patients with MBC treated between 2008 and 2016 in 18 French comprehensive cancer centers. The data analysis was conducted from July 16, 2020, to April 1, 2022.Main Outcomes and MeasuresThe main outcome was overall survival (OS), and the secondary outcome was progression-free survival under first-line treatments (PFS1).ResultsThe median (range) age was 60.0 (22.0-103.0) years. Among 15 054 patients with MBC, 4671 (31%) had ERBB2-low MBC and 10 383 (69%) had ERBB2-zero MBC. The proportion of ERBB2-low cancers was higher among patients with hormone receptor–positive MBC than those with hormone receptor–negative disease (4083 patients [33.0%] vs 588 patients [21.0%]). With a median follow-up of 49.5 months (95% CI, 48.6-50.4 months), the median OS of the ERBB2-low group was 38.0 months (95% CI, 36.4-40.5 months) compared with 33.9 months (95% CI, 32.9-34.9 months) for the ERBB2-zero group (P &lt; .001). After adjustment for age, visceral metastases, number of metastatic sites, de novo disease, period of care, and hormone receptor status, patients with ERBB2-low MBC had slightly better OS compared with patients with ERBB2-zero MBC (adjusted hazard ratio, 0.95; 95% CI, 0.91-0.99; P = .02). In contrast, PFS1 did not differ by ERBB2 status (adjusted hazard ratio, 0.99; 95% CI, 0.95-1.02; P = .45). No significant differences in OS and PFS1 were observed in multivariate analyses by hormone receptor status and types of frontline treatment.Conclusions and RelevanceIn this large cohort study, patients with ERBB2-low MBC had a slightly better OS than those with completely ERBB2-zero tumors, but identical PFS1, which could help guide treatment selection.
Methods of Analysis for the Determination of Veterinary Drugs in Food: Focus on Antimicrobials
Authors: Spisso Bernardete F. , Pereira Mararlene U. , Ferreira Rosana G. 
Published: September 2022

Abstract
An overview of the methods of analysis that are currently being used for the determination of veterinary drugs in food is presented. Hyphenated techniques, mainly those based on the coupling of chromatographic separation and mass spectrometry detection have proven to be more appropriate. Liquid chromatography–tandem mass spectrometry (LC–MS/MS) with quadrupole mass analyzers is still the most used analytical technique for the purpose, but high‐resolution mass analyzers are becoming more accessible and more frequently employed, due to their capability of untargeted screening, elucidation power of molecular structures of unknown substances and retrospective analysis. Among the sample preparation methods, modified QuEChERS extractions have brought considerable benefits regarding simplifications of sample preparation steps, resulting in cheaper and high throughput methods for veterinary drugs in complex matrices such as foods. A trend to implement more cost‐effective methods has led to attempts to include veterinary drugs, pesticides, mycotoxins, and environmental contaminants in multi‐residue mega‐methods.
Prevention of Noise Current Generation in Tin‐Based Lead‐Free Perovskites for Highly Sensitive Photodetection
Authors: Jang Woongsik , Kim Kyusun , Kim Byung Gi , Nam Jeong‐Seok , Jeon Il , Wang Dong Hwan 
Published: September 2022

AbstractLead (Pb) halide perovskites have attracted significant attention in the field of optoelectronics. However, due to the disadvantages associated with the presence of Pb in perovskite, its use should be minimized, if not completely eliminated. Herein, an efficient Pb‐free Sn‐based halide perovskite photodetector (PD) that is sensitive to visible and near‐infrared light is developed. The Sn perovskite is characterized with low toxicity and a narrow bandgap, and exhibits lower shunt leakage and a higher built‐in potential compared with a Pb‐based perovskite. Also, the relatively stronger bond strength between Sn and iodine ions in comparison with that observed in the Pb‐based perovskite effectively prevents charge injections that are vulnerable to dark current suppression. The Sn‐based perovskite PD demonstrates a high signal‐to‐noise ratio (SNR) of 51.12 dB, as well as an excellent cut‐off frequency of 763 kHz. To the best knowledge, this device is one of the fastest and most efficient photodiode‐type Sn‐based perovskite PDs developed to date. Unlike the Pb‐based perovskite device, the Sn‐based perovskite PD retains its high SNR over time. This effect may be attributed to the low movement of ion vacancies and degree of vertical shunt leakage in the perovskite material.
All in One‐Chip, Electrolyte‐Gated Graphene Amplitude Modulator, Saturable Absorber Mirror and Metrological Frequency‐Tuner in the 2–5 THz Range
Authors: Di Gaspare Alessandra , Pogna Eva Arianna Aurelia , Riccardi Elisa , Sarfraz Syed Muhammad Abouzar , Scamarcio Gaetano , Vitiello Miriam Serena 
Published: September 2022

AbstractLayered 2D materials display unique optical and electrical properties that can enable manipulation, propagation, and detection of electromagnetic waves over a broad spectral range, with a high level of control, offering the potential to activate different functionalities, by optical or electrical means, in a single chip. Here, a compact optoelectronic device behaving as an amplitude modulator, saturable absorber mirror (SA mirror), and frequency‐tuner is conceived at terahertz (THz) frequencies. It comprises a gate‐tunable single layer graphene (SLG), embedded in a quarter‐wave cavity, operating in the 1–5 THz range. The use of electrolyte ionic liquid gate ensures 40% optical amplitude modulation depth. Z‐scan self‐mixing interferometry reveals 60% reflectivity modulation, with ≈4.5 W cm−2 saturation intensity. By integrating the modulator/SA mirror with a heterogeneous THz quantum cascade laser frequency comb, in an external cavity configuration, fine‐tuning of the intermode beatnote frequency is also demonstrated. This opens intriguing perspectives for short pulse generation, phase‐locking, frequency tuning/chirping, phase modulation, and metrological referencing, inter alia.
Flexible Electro‐Optical Arrays for Simultaneous Multi‐Site Colocalized Spatiotemporal Cardiac Mapping and Modulation
Authors: Obaid Sofian N. , Chen Zhiyuan , Madrid Micah , Lin Zexu , Tian Jinbi , Humphreys Camille , Adams Jillian , Daza Nicolas , Balansag Jade , Efimov Igor R. , Lu Luyao 
Published: September 2022

AbstractBioelectronic devices that allow simultaneous accurate monitoring and control of the spatiotemporal patterns of cardiac activity provide an effective means to understand the mechanisms and optimize therapeutic strategies for heart disease. Optogenetics is a promising technology for cardiac research due to its advantages such as cell‐type selectivity and high space‐time resolution, but its efficacy is limited by the insufficient number of modulation channels and lack of simultaneous spatiotemporal mapping capabilities in current implantable cardiac optogenetics tools available for in vivo investigations. Here, soft implantable electro‐optical cardiac devices integrating multilayered highly uniform arrays of transparent microelectrodes and multicolor light‐emitting diodes in thin, flexible platforms are designed for mechanically compliant high‐content high‐precision electrical mapping and single‐/multi‐site optogenetics and electrical stimulation without light‐induced artifacts. Systematic benchtop characterizations, together with ex vivo and in vivo evaluations on healthy and diseased small animal hearts and human cardiac slices demonstrate their functionalities in real‐time spatiotemporal mapping and control of cardiac rhythm and function, with broad applications in basic and ultimately clinical cardiology.
Redox‐Neutral Synthesis of Polycyclic Azaheterocycles via Cobalt‐Catalyzed Hydroarylation/Annulation of Maleimides
Authors: He Yequan , Li Wenwei , Zhou Honggui , Zeng Ge , Chen Zhongyan , Ge Jing‐Yuan , Lv Ningning , Chen Jiuxi 
Published: September 2022

AbstractHerein, we report a cobalt‐catalyzed hydroarylation of maleimides followed by an annulation sequence for the synthesis of polycyclic azaheterocycles in one pot. The reaction proceeds under redox‐neutral conditions and is compatible with various functional groups. Notably, the as‐prepared product exhibits potential photophysical properties.magnified image
Umbilical Cord Mesenchymal Stem Cells Promoting Spinal Cord Injury Repair Visually Monitored by AIE‐Tat Nanoparticles
Authors: Xie Peigen , Ling Haiqian , Pang Mao , He Lei , Zhuang Zeyan , Zhang Guiling , Chen Zihao , Weng Chuanggui , Cheng Sijin , Jiao Ju , Zhao Zujin , Tang Ben Zhong , Rong Limin 
Published: September 2022

AbstractSpinal cord injury (SCI) is a severe body trauma that can cause permanent loss of somatic nerve function and lacks effective treatment. Transplantation of stem cells is a promising therapeutic approach for SCI but faces with the difficulty of long‐term tracking of stem cells in vivo precisely. Herein, this work wishes to report a kind of umbilical cord mesenchymal stem cells (UC‐MSCs) labeled with aggregation‐induced emission (AIE)‐Tat nanoparticles (NPs) for tracing the repair and treatment of SCI. These AIE‐Tat NPs have strong fluorescence, good biocompatibility, and long‐term tracking ability with a high signal‐noise ratio. The labeling of AIE‐Tat NPs does not induce adverse effects on the activity and performance of UC‐MSCs. The fluorescence signal of the UC‐MSCs can be monitored for up to 28 days, reflecting the viability, colonization, and function of the transplanted UC‐MSCs. The transplantation of UC‐MSCs can secrete nerve growth factors and maintain the viability of cells in the highly reactive oxygen species microenvironment, leading to effective recovery of injured spinal cord, which is further confirmed by the behavioral rehabilitation and histopathological results. These findings demonstrate that long‐term tracking of UC‐MSCs labeled with AIE‐Tat NPs is a promising method to monitor stem cell transplantation therapy for SCI.
Hydrothermally Grown Dual‐Phase Heterogeneous Electrocatalysts for Highly Efficient Rechargeable Metal‐Air Batteries with Long‐Term Stability
Authors: Balamurugan Chandran , Lee Changhoon , Cho Kyusang , Kim Jehan , Park Byoungwook , Pak Yusin , Kong Jaemin , Kwon Sooncheol 
Published: September 2022

AbstractMetal‐air batteries as alternatives to the existing lithium‐ion battery are becoming increasingly attractive sources of power due to their high energy‐cost competitiveness and inherent safety; however, their low oxygen evolution and reduction reaction (OER/ORR) performance and poor operational stability must be overcome prior to commercialization. Herein, it is demonstrated that a novel class of hydrothermally grown dual‐phase heterogeneous electrocatalysts, in which silver‐manganese (AgMn) heterometal nanoparticles are anchored on top of 2D nanosheet‐like nickel vanadium oxide (NiV2O6), allows an enlarged surface area and efficient charge transfer/redistribution, resulting in a bifunctional OER/ORR superior to those of conventional Pt/C or RuO2. The dual‐phase NiV2O6/AgMn catalysts on the air cathode of a zinc‐air battery lead to a stable discharge–charge voltage gap of 0.83 V at 50 mA cm−2, with a specific capacity of 660 mAh g−1 and life cycle stabilities of more than 146 h at 10 mA cm−2 and 11 h at 50 mA cm−2. The proposed new class of dual‐phase NiV2O6/AgMn catalysts are successfully applied as pouch‐type zinc‐air batteries with long‐term stability over 33.9 h at 10 mA cm−2.
Mechanical Intelligence (MI): A Bioinspired Concept for Transforming Engineering Design
Authors: Khaheshi Ali , Rajabi Hamed 
Published: September 2022

AbstractDespite significant scientific advances in the past decades, most structures around us are static and ironically outdated from a technological perspective. Static structures have limited efficiency and durability and typically perform only a single task. Adaptive structures, in contrast, adjust to different conditions, tasks, and functions. They not only offer multi‐functionality but also enhanced efficiency and durability. Despite their obvious advantages over conventional structures, adaptive structures have only been limitedly used in everyday life applications. This is because adaptive structures often require sophisticated sensing, feedback, and controls, which make them costly, heavy, and complicated. To overcome this problem, here the concept of Mechanical Intelligence (MI) is introduced to promote the development of engineering systems that adapt to circumstances in a passive‐automatic way. MI will offer a new paradigm for designing structural components with superior capabilities. As adaptability has been rewarded throughout evolution, nature provides one of the richest sources of inspiration for developing adaptive structures. MI explores nature‐inspired mechanisms for automatic adaptability and translates them into a new generation of mechanically intelligent components. MI structures, presenting widely accessible bioinspired solutions for adaptability, will facilitate more inclusive and sustainable industrial development, reflective of Goal 9 of the 2030 Agenda for Sustainable Development.