bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASSESSMENT OF THE INFLUENCE OF RISK FACTORS ON THE COURSE OF CHRONIC KIDNEY DISEASE AND PROGRESSION OF RENAL FAILURE
Authors: НУРСУЛТАНОВА ЛИЗА НАРИМАНОВНА 
Published: September 2022

Около сорока процентов взрослых, имеют завышенный риск развития приобретенного заболевания почек, в их числе существенное количество заболевших с артериальной гипертензией, метаболическим синдромом и диабетом. В период с 01.10.2020 г. по 30.09.2021 г. было проведено популяционное исследование в Кызылординской области. Для определения частоты ранних стадий ХБП была сформирована выборка, состоявшая из лиц казахской национальности - резидентов Кызылординской области 19 лет и старше. Источниками для отбора больных в исследование служили 3 группы. В базу исследования положен многоэтапный принцип сбора, статистической обработки и изучения приобретенной информации. В результате исследования выявилась: независимыми предикторами увеличения уровня альбуминурии являются наличие сахарного диабета, табакокурение, снижение скорости бочковой фильтрации, альбумина сыворотки крови, а также увеличение концентрации общего холестерина, индекса массы миокарда левого желудочка и возраста. К независимым факторам, определяющим снижение скорости клубочковой фильтрации, относятся: увеличение возраста, уровня урикемии, альбуминурии и диастолического АД, уменьшение толщины паренхимы почек, а также женский пол.
About forty percent of adults are at increased risk of developing acquired kidney disease, including a significant number of those with hypertension, metabolic syndrome, and diabetes. In the period from 10/01/2020 to 09/30/2021, a population study was conducted in the Kyzylorda region. To determine the frequency of early stages of CKD, a sample was formed, consisting of persons of Kazakh nationality - residents of the Kyzylorda region aged 19 years and older. 3 groups served as sources for the selection of patients in the study. The study is based on a multi-stage principle of collecting, statistical processing and studying the acquired information. As a result of the study, it was revealed that independent predictors of an increase in the level of albuminuria are the presence of diabetes mellitus, smoking, a decrease in the barrel filtration rate, blood serum albumin, as well as an increase in the concentration of total cholesterol, the mass index of the left ventricular myocardium and age. Independent factors that determine the decrease in glomerular filtration rate include: an increase in age, the level of uricemia, albuminuria and diastolic blood pressure, a decrease in the thickness of the renal parenchyma, as well as female sex
FREQUENCY OF POST-VACCINATION REACTIONS AFTER COVID-19 VACCINATION
Authors: ИСАЕВА А.М. , РУСТАМОВА Ф.Е. , МУХАМБЕТОВА Р.У. , КОЖАШЕВА А.Е. , УРАЗБЕКОВА А.А. , МУРАТБЕКОВА А.А. , МУРАТКАЗИНОВА А.С. , МАКИНА К.С. 
Published: September 2022

Проведен анализ среди 100 терапевтов-резидентов НАО «Национальный медицинский университет» имени С.Д.Асфендиярова, для выявления побочных эффектов после вакцинации от COVID-19. В исследование вошли следующие вакцины: Pfizer, Спутник V, Vero Cell и QazVac. В нашем исследовании мужчины составили 52% всех респондентов (n=52). В исследовании участвовали резиденты от 24 до 27 лет. Средний возраст участников составил 25,5±0,7 лет. По результатам нашего исследования, доля побочных эффектов после прививания Pfizer составила 53,3%. Причиной высокого показателя является количество резидентов, прививавшихся вакциной Pfizer (n=2). Отечественный QazVac показал следующий результат - 30%. 25,7% - это доля побочных эффектов после прививания китайской вакциной Vero Cell. После прививания российским Спутником V доля побочных эффектов составила 33,8%
An analysis was carried out among 100 resident therapists of NJSC "National Medical University" named after S.D. Asfendiyarov, to identify side effects after vaccination against COVID-19. The following vaccines were included in the study: Pfizer, Sputnik V, Vero Cell and QazVac. In our study, men accounted for 52% of all respondents (n=52). The study involved residents from 24 to 27 years old. The average age of the participants was 25.5±0.7 years. According to the results of our study, the proportion of side effects after inoculation with Pfizer was 53.3%. The reason for the high rate is the number of residents vaccinated with the Pfizer vaccine (n=2). Domestic QazVac showed the following result - 30%. 25.7% is the share of side effects after vaccination with the Chinese Vero Cell vaccine. After inoculation with the Russian Sputnik V, the proportion of side effects was 33.8%.
THE USE OF MODERN TECHNOLOGIES IN THE PREVENTION OF DISEASES ASSOCIATED WITH AIR POLLUTION
Authors: АЛИМКУЛОВА М.Ю. , АБИКУЛОВА А.К. , СЕЙДУАНОВА Л.Б. , АХТАЕВА Н.С. 
Published: September 2022

Проблема загрязнения воздуха является одной из актуальных проблем во многих странах мира. По данным ВОЗ в 2019 г. более 90% населения планеты проживало в районах, где концентрация частиц PM2,5 превышала рекомендованные параметры. Загрязнение атмосферного воздуха губительно воздействует не только на окружающую среду, но и наносит вред здоровью людей, приводя к развитию заболеваний сердечно-сосудистой, дыхательной систем и т.д. В этом контексте технологии смартфонов представляют значительный потенциал для улучшения реагирования на атмосферные опасности, позволяя предоставлять персонализированную и легкодоступную медицинскую информацию.
The problem of air pollution is one of the urgent problems in many countries of the world. According to WHO, in 2019, more than 90% of the world's population lived in areas where the concentration of PM2,5 particles exceeded the recommended parameters. Atmospheric air pollution has a detrimental effect not only on the environment, but also harms human health, leading to the development of diseases of the cardiovascular, respiratory systems, etc. In this context, smartphone technologies represent a significant potential for improving the response to atmospheric hazards, allowing the provision of personalized and easily accessible medical information.
SAFETY ASSESSMENT OF PLANT RAW MATERIALS CROCUS ALATAVICUS
Authors: Алламбергенова З.Б. , Сакипова З.Б. , Алиев Н.У. , Кожанова К.К. , Кадырбаева Г.М. 
Published: September 2022

В данной статье приведены результаты оценки безопасности растительного сырья Сrocus alatavicus. Определены содержания: тяжелых металлов и мышьяка, радионуклидов (стронция-90 и цезия-137), остаточное количество пестицидов, показатель - микробиологическая чистота.
This article presents the results of a safety assessment of the plant material Crocus alatavicus. The following contents were determined: heavy metals and arsenic, radionuclides (strontium-90 and cesium-137), the residual amount of pesticides, the indicator is microbiological purity.
Grupos funcionales del fitoplancton en el norte del ecosistema de la Corriente de Humboldt
Authors: Bernales Avy , Tam Jorge , Sánchez Sonia , Jacobo Nelly , Chang Flor , Delgado Elcira , Romero Liz , Demarcq H. 
Published: September 2022

El Norte del ecosistema de la Corriente de Humboldt, localizado a lo largo del Sudeste del Océano Pacífico, frente a Perú, es considerado uno de los más productivos sistemas naturales en el mundo, siendo de gran relevancia el estudio del fitoplancton como base de la trama trófica marina. Tomando en cuenta las relaciones entre la superficie celular, biovolumen y máxima dimensión lineal de las células de las especies del fitoplancton, se encontraron 140 especies en el grupo funcional ‘R‘ (especies ruderales, adaptables a condiciones altas de mezcla); 133 especies en el grupo funcional ‘S’ (especies Stress-tolerantes, predominantes en condiciones oligotróficas y de alta luz) y 19 en el grupo funcional ‘C’ (especies colonizadoras, oportunistas, predominantes en condiciones mesotróficas y de alta luz). En el grupo funcional R destacaron las diatomeas elongadas, pennadas, dispuestas en cadenas; en el grupo funcional S se encontraron dinoflagelados, diatomeas centrales grandes y silicoflagelados; mientras que, en el grupo funcional C destacaron cocolitofóridos, algunos dinoflagelados mixotróficos y fitoflagelados. Los porcentajes de coincidencia entre la clasificación morfométrica de grupos funcionales del presente estudio y la clasificación ecológica, estuvieron entre 52 y 90%. Se propone el uso de estos grupos para evaluar las variaciones espacio-temporales del fitoplancton y su relación con las condiciones ambientales en el Norte del ecosistema de la Corriente de Humboldt, cuyos niveles de turbulencia son menores al de los fiordos chilenos.
Abundancia y distribución de mamíferos marinos y su relación con presencia de presas. Antar XXVI, verano austral 2019
Authors: Aguilar-Arakaki Regina , Ochoa-Madrid Manuel 
Published: September 2022

El objetivo de la publicación es determinar abundancia y distribución de mamíferos marinos y su relación con la abundancia de presas y condiciones ambientales en el Estrecho de Bransfield y alrededores de isla Elefante durante la Campaña Antar XXVI. Los avistamientos fueron realizados por dos observadores entre el 31 de diciembre 2018 y 15 de enero 2019 en el puente de mando del BAP Carrasco durante las horas de luz (06:00 – 22:00), siguiendo un trayecto determinado por el Imarpe. Se observaron 323 cetáceos; de cuatro especies identificadas, la más abundante fue la ballena jorobada Megaptera novaeangliae, con 134 avistamientos y 207 individuos; las otras especies identificadas fueron: ballena de aleta Balaenoptera physalus (31 avistamientos, 49 individuos), calderón de aleta larga o ballena piloto Globicephala melas (1 avistamiento, 25 individuos) y orca Orcinus orca (1 avistamiento, 2 individuos). La ballena jorobada estuvo agregada principalmente en el Estrecho de Bransfield, asociada a cortas distancias de la costa y presencia dispersa de krill, mientras que la ballena de aleta se registró mayormente en los alrededores de isla Elefante, asociada a mayores valores de temperatura superficial del mar y profundidad, así como mayores volúmenes de eufáusidos.
Impact of COVID-19 pandemic on health-related quality of life, personal resilience, and academic performance difficulties of recovered patients in Egypt
Authors: Hantira Neama Yousef Mohamed , Abdelaziz Maha Mahmoud , El Demerdash Doaa Ali , Ahmed Hend Abo Elsoud 
Published: September 2022

Background: In early March 2020, the World Health Organization (WHO) declared Coronavirus disease-2019 (COVID-19) to be a global pandemic. This fatal disease may have a severe impact on quality of life, personal resilience, and academic performance. Aim of the study: To assess the impact of the COVID-19 pandemic on the health-related quality of life, resilience, and academic performance difficulties among recovered patients in Egypt. Study Design: A descriptive exploratory cross sectional research design was used. Study Settings: The current study was conducted among Egyptian subjects living in 27 governorates using an online survey method. Study Subjects: The study was carried out on a 405 Egyptian who were responded to the online questionnaire. Data collection tools: Health-Related Quality of Life, Personal Resilience and Academic Performance Difficulties among Recovered COVID – 19 Patients Assessment Survey Questionnaire was used which include five main parts (part I, & II to assess sociodemographic data, and history and risk factors, part III to Health-Related Quality of Life, part IV to assess personal resilience, and part V to assess the academic performance).
Development of multiplex-PCR for identification of 8 genotypes of human papillomavirus (HPV)
Authors: Chegini Shahin Nezamivand , Nazemi Ali 
Published: September 2022

Contamination with human papillomavirus (HPV) is one of the most significant risk factors for developing genital cancer. Since there is no possibility of detecting the virus and its subtypes using conventional cell culture, biochemical and serological methods, the molecular methods including multiplex Polymerase Chain Reaction (PCR) have specific importance in accurate, rapid and definite diagnosis of this virus. The present study was done to identify the 8 routine genotypes of the papilloma virus using the novel Multiplex-PCR (M-PCR). Twenty epithelial cells of vaginal samples were collected from the molecular diagnosis laboratory. Novel primers for diagnosis of 16, 18, 31, 33, 52, 53, 56, and 58 genotypes of the HPV were designed using the NCBI website and BLAST tool. We specifically designed and synthesized based on different gene regions (E6-7 and L2) and optimized the reaction using the samples of 8 investigated types. Genomic DNA was extracted from the samples and the M-PCR technique was used to detect HPV genotypes. Types 52, 53 and 31 were detected in 5 samples (25%). The M-PCR system developed in this project was able to identify 7 types with 100% specificity and without reacting with other types.
Spectrum of lung pathology in medicolegal autopsies at rural teaching hospital
Authors: Kale Apurva , Passi Rashim , Karle Ravindra R. 
Published: September 2022

Background: Lungs are the major organs involved by a number of infectious, inflammatory and occupational hazards. They are also involved secondarily by all forms of terminal events like cardiovascular events. Autopsy is a part of pathology that serves as an important tool to identify the cause and manner of death and to learn about methods to prevent them. Methods: This is a retrospective study conducted on the autopsy specimens received in the department of pathology from 1 January 2020 to 31 December 2021. Gross findings were noted at the time of autopsy and the specimen was subjected to routine histopathological processing and hematoxylin and eosin staining. Histopathological findings were noted. Results: Out of total 78 cases, 30.17% shows Congestion and oedema, 24.65% shows Pneumonia. 10.95% and 8.21% shows interstitial changes in the form of interstitial pneumonia or mononuclear interstitial infiltrate and Diffuse alveolar damage respectively, 6.84% shows emphysematous changes and 5.84% shows chronic passive venous congestion. 4.1% cases shows findings of tuberculosis and only 1 case was of lung abscess, metastatic papillary renal cell carcinoma and fibrin thrombi each. Highest number of cases (32) belonged to 16-30 age group. Least number of cases (2) were from >75 age group.
Molecular detection of human papillomavirus DNA in dysplastic and non-dysplastic oral lichen planus patients
Authors: Vijayan Aswathy K. , Muthukrishnan Arvind , Vijayan Aswathy K. 
Published: September 2022

Introduction: Oral Lichen Planus (OLP) is a chronic inflammatory disease of cell-mediated dysregulation characterized by relapses and remissions. The aetiology of OLP has been extensively studied for decades. The pathogenesis is unclear with a debatable malignant transformation. The pathogenesis and malignant transformation of OLP may be affected by viruses such as Hepatitis C Virus (HCV), Human Papillomavirus (HPV), Herpes Simplex Virus (HSV), and stress. HPV has been proved to be an etiological agent in oropharyngeal cancers and non-tobacco-associated leukoplakia. The role of human papillomavirus in the pathogenesis of OLP and its malignant transformation has to be studied extensively. Aim: This study aims to detect the presence of HPV DNA in the biopsy samples of dysplastic and non-dysplastic OLP and thus determine the role the virus played in the malignant transformation of OLP. Materials and Methods: Biopsy samples comprising 250 OLP tissues were collected. The DNA was extracted from the fixed tissue by using the Cetyltrimethylammonium bromide (CTAB) method. Polymerase Chain Reaction (PCR) was performed using primers to amplify the HPV E6 gene. Results: Hundred and three out of 250 (41.2%) OLP cases were positive for HPV DNA.
Compared cadmium adsorption from biochar and magnetite biochar in water
Authors: Jasim Ali Mohammed , Alzurfi Sadiq Kadhum Lafta 
Published: September 2022

Water safety is a prerequisite for sustainable global quantitative and qualitative development. Heavy metal pollution has become a major problem in our environment, where traditional heavy metal processing techniques were unsuccessful and expensive. In this study, biochar and magnetite biochar have been used as an efficient, low-cost, safe, and environmentally friendly method for heavy metal removal such as cadmium. The biochar has been prepared from palm fronds and then activated by sodium hydroxide before treatment with two concentrations (5 ppm and 10 ppm) of cadmium in the water. The biochar (BC) had a positive effect on improving the efficiency of removing cadmium (II). The percentage to remove cadmium was 98% when we added 0.5 g of biochar to the solution. On the other hand, we have prepared composite materials by mixing biochar with magnetite at the mole ratio of (2:1) to prepare magnetite-biochar (MBC). A property was added to the biochar prepared by adding Fe3O4 to the biochar, which led to the activation of the effective aggregates with a significant improvement in the adsorption performance of heavy metals while increasing the removal efficiency up to 100%.
Close link between breast cancer & apoptosis
Authors: Alanazi Rakan J. , Fallatah Deema I. , Helal G. , Alqarni Adel M. , Aloraini Ghfren S. , Alonazi Fahad N. , Alrabia Mohammed W. , Alruwaili Ahoud M. , Alenzi Faris Q. B. 
Published: September 2022

The mammary gland represents an unique model system to allow investigation of factors that underpin biological initiation of apoptotic processes and related signal transduction pathways. One advantage is that the mammary gland, unlike most other organs, has the capacity to go through many cycles of growth, differentiation and anatomical structural development. Indeed, the mammary gland has evolved highly efficient processes (that straddle both lactation and post-lactational phases) which regulate the balance between cell death and proliferation. This paper will discuss the molecular and cellular aspects of apoptosis in the mammary gland with a particular emphasis on the role of apoptosis in breast cancer development.
Phenotypic and genotypic characterization of macrolide resistance in Staphylococcus aureus isolates from wound infection
Authors: Ali Haider Abdul-Amir , Al-Amara Saad Shakir Mahdi 
Published: September 2022

Microbiologists are increasingly concerned about the rise in S. aureus MLSB (macrolide, lincosamide, streptogramin B) drug resistance. Clindamycin has been effective in treating infections by S. aureus, and the variations in clindamycin sensitivity patterns cause treatment to fail. Inducible clindamycin resistance in S. aureus is expressed via erythromycin ribosome methylase genes. In the current study, 25 S. aureus isolates were identified by conventional chemical tests and the Vitek®2 system. Specific primers were used for the amplification of Macrolide genes by PCR. Among 25 S. aureus isolates, 23(92%) isolates were methicillin resistant and 2(8%) isolates were methicilin sensitive. The 5(20%) isolates showed resistance to Erythromycin and sensitivity to Clindamycin with a positive D test which was identified as inducible MLSB, while 2(8%) isolates showed resistance criteria for both Erythromycin and Clindamycin which identity as a constitutive MLSB and 18(92%) isolates were given the sensitivity for both Erythromycin and Clindamycin. The erm resistance genes (ermA, ermB, ermC, ermF, and ermG) were detected in 5(20%), 17(68%), 25(100%), 24(96%),11(44%) respectively. The D-test, and Vitek ®2 system should be routinely done to avoid treatment failure due to clindamycin resistance.
Impact of sodium hypochlorite irrigant on fatigue resistance of different nickel-titanium instruments
Authors: Hamdan Zainab Abdulhasan , Al-Zaka Iman Mohammed 
Published: September 2022

Aim: The purpose of this study was to investigate the resistant of three NiTi files, ProTaper (PTN), Hyflex EDM and 2Shape (TS) to cyclic fatigue after being immersed in a 2.5 percent NaOCl irrigant solution in different times (1&5 minutes) at 37°C. Materials and Methods: Seventy-two heat treated files used in this study, divided into three main groups (n=24) according to their metallurgy group-1: PTN, group-2: Hyflex EDM and group-3: TS files each group then subdivided into three subgroups, subgroup-1 immersed in 2.5 percent NaOCl for 1minute at 37°C subgroup-2 immersed in 2.5 percent NaOCl for 5 minutes at 37°C and subgroup-3 did not undergo any immersion as a control group. All files were put through cyclic fatigue testing in a digital water bath at 37°C to imitate body temperature in a stainless-steel artificial canal. The time to fracture was recorded in minutes, then by multiplying the time to fracture by the rotations per minute, the number of cycles to fracture (NCF) was calculated. The data were checked for normality before running a one-way ANOVA with a post hoc test.
The urgence of the criminal act of sexual violence as the empowerment of women's rights
Authors: Judiasih Sonny Dewi , Yuanitasari Deviana , Kusmayanti Hazar 
Published: September 2022

Efforts to discriminate against women in the form of actions carried out based on gender differences, harming or endangering women. Research is preferred in the form of research that prioritizes secondary data The importance of the existence of a law that specifically regulates sexual violence is as follows: 1) The number of sexual violence in Indonesia continues to increase. 2) Cases of sexual violence have caused a lot of harm to women as parties who often become victims. 3) There is no deterrent effect for perpetrators after the incident 4) Enforcement of cases of sexual violence often does not have a victim's perspective. 5) Lack of legal instruments that are able to maximally resolve any sexual violence that has occurred, especially from the aspect of the availability of regulations. 6) In order to reduce the number of sexual violence, it is necessary to optimize the function of the commissions that oversee various sectors of sexual violence cases. 7) The prosecution of cases of sexual violence is considered less firm. 8) The importance of maximizing the function of rehabilitation and proper recovery for victims of sexual violence. 9) Access to seek, seek, and obtain justice for victims 10)
Forgiveness and peace agreement as an implementation of living law in certain crimes in Indonesia
Authors: Sulistiani Lies , Kusmayanti Hazar , Rusmiati Elis , Fakhriah Efa Laela 
Published: September 2022

Indonesian criminal law system does not regulate pacific settlement mechanisms in the settlement of criminal cases. This does not correspond to reality where for certain types of crime, members of the society tend to resort to pacific settlements such as giving/seeking forgiveness or making peace agreements, which is done to make peace between the perpetrators and their victims, thus settling the case. This article is written based on research that is aimed at finding out the relationship between forgiveness and peace agreements, and the legal system that exist in Indonesia; analyzing the cause/motivation behind the preference for peaceful settlement mechanisms over criminal proceeding at a judiciary, and; analyzing the response of law enforcement officers to the result of peace agreement and reconciliation between victims and perpetrators. Several conclusions were drawn as the results of this study; first, forgiveness and peace agreements in pacific settlements of criminal cases are carried out based on consensual basis between the parties involved; second, forgiveness and peace agreements in pacific settlement of criminal cases embody some of the values contained in the state ideology of Indonesia.