bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of dog control strategies
Authors: Duncan-Sutherland Natasha , Hunt Mareta , Alatini Moses , Shepherd Michael , Kool Bridget 
Published: December 2022

Objectives(1) To explore the relationship between regionally implemented dog control strategies and dog bite injuries (DBIs) and (2) to evaluate current implementation of dog control strategies.MethodsObservational study using a nationwide online survey of territorial authorities (TAs). Domains of interest included complaints for attacks on people, dog population, primary and secondary prevention strategies, resourcing and perspectives of current strategies. Quantitative variables were compared with DBI Accident Compensation Corporation (ACC) claims by region from 2014 to 2018.ResultsTwo-thirds of TAs (70%; n=47/67) responded to the survey. No clear relationship was observed between DBIs and: registered dog population, proportion sterilisations or microchipping, classifications due to dog behaviour, or existing limited resourcing. Legislated breeds and infringements for failure to control a dog or non-registration were higher in areas with greater DBIs. Educational messages varied widely and were predominantly victim directed (67%; n=71/106). Complaints for dog attacks on people were lower than DBIs in most areas, with no formal cross-agency notification policies. Few prosecutions or dog destruction orders were made.ConclusionsRegional inequity in DBIs could not be explained by differences in the registered dog population or dog control strategies. Minimal and inequitable resourcing exists to implement current dog control strategies and provide owner-directed education. Gaps in legislation include environmental barrier requirements for all dogs (leash/muzzle use, adequate fencing), notification of incidents and child protection. Partnership with the Indigenous community (Māori) and other community groups will be required to implement these measures successfully.
Association between traumatic brain injury and suicidality using a mediation approach and MarketScan
Authors: Miller Gabrielle F. , Zhou Hong , Peterson Alexis B. , Swedo Elizabeth , Holland Kristin , Kresnow Marcie-jo 
Published: December 2022

IntroductionNegative outcomes, including suicidal ideation/attempts, are a major public health concern, particularly among individuals who sustain a traumatic brain injury (TBI). TBI is associated with high rates of postinjury substance use, psychiatric disorders, post-traumatic stress disorder and sleep disturbances. This study examines the mediation effects of substance use, psychiatric disorder and sleep disorder on the associations between TBI and suicidal ideation/attempts.MethodsA matched case–control study using data from MarketScan databases for private health insurance and Medicaid from October 2015 to December 2018 estimated the association between TBI and suicidal ideation/attempts using a mediation approach. Individuals less than 65 years of age were included.ResultsIn the Medicaid sample, psychiatric disorders mediated 22.4% of the total effect between TBI and suicidal ideation/attempt, while substance use disorders other than opioid use disorder mediated 7.47%. In the private health insurance sample, psychiatric disorders mediated 3.97% of the total effect, opioid use disorders mediated 2.08% of the total effect and sleep disorder mediated 1.25% of the total effect.ConclusionsMediators explained less than 30% of the relationship between TBI and suicidal ideation/attempt. Findings reinforce the importance of primary prevention of TBI and monitoring patients with a TBI for risk of suicide in the first 6–12 months following injury.
Addressing discrepancies in estimates of road traffic deaths and injuries in Ethiopia
Authors: Neki Kazuyuki , Gutierrez Hialy , Mitra Sudeshna , Temesgen Awoke M , Mbugua Leah Watetu , Balasubramaniyan Ramshankar , Winer Mercer , Roberts Jaeda , Vos Theo , Hamilton Erin , Naghavi Mohsen , Harrison James E , Job Soames , Bhalla Kavi 
Published: December 2022

BackgroundThere are large discrepancies between official statistics of traffic injuries in African countries and estimates from the Global Burden of Disease (GBD) study and WHO’s Global Status Reports on Road Safety (GSRRS). We sought to assess the magnitude of the discrepancy in Ethiopia, its implications and how it can be addressed.MethodsWe systematically searched for nationally representative epidemiological data sources for road traffic injuries and vehicle ownership in Ethiopia and compared estimates with those from GBD and GSRRS.FindingsGBD and GSRRS estimates vary substantially across revisions and across projects. GSRRS-2018 estimates of deaths (27 326 in 2016) are more than three times GBD-2019 estimates (8718), and these estimates have non-overlapping uncertainty ranges. GSRRS estimates align well with the 2016 Demographic and Health Survey (DHS-2016; 27 838 deaths, 95th CI: 15 938 to 39 738). Official statistics are much lower (5118 deaths in 2018) than all estimates. GBD-2019 estimates of serious non-fatal injuries are consistent with DHS-2016 estimates (106 050 injuries, 95th CI: 81 728 to 130 372) and older estimates from the 2003 World Health Survey. Data from five surveys confirm that vehicle ownership levels in Ethiopia are much lower than in other countries in the region.InterpretationInclusion of data from national health surveys in GBD and GSRRS can help reduce discrepancies in estimates of deaths and support their use in highlighting under-reporting in official statistics and advocating for better prioritisation of road safety in the national policy agenda. GBD methods for estimating serious non-fatal injuries should be strengthened to allow monitoring progress towards Sustainable Development Goal target 3.6.
Costs attributable to criminal justice involvement in injuries: a systematic review
Authors: Miller Gabrielle F. , Barnett Sarah Beth , Wulz Avital Rachelle , Luo Feijun , Florence Curtis 
Published: December 2022

ContextCosts related to criminal justice are an important component of the economic burden of injuries; such costs could include police involvement, judicial and corrections costs, among others. If the literature has sufficient information on the criminal justice costs related to injury, it could be added to existing estimates of the economic burden of injury.ObjectiveTo examine research on injury-related criminal justice costs, and what extent cost information is available by type of injury.Data sourcesMedline, PsycINFO, Sociological Abstracts ProQuest, EconLit and National Criminal Justice Reference Service were searched from 1998 to 2021.Data extractionPreferred Reporting Items for Systematic reviews and Meta-Analyses was followed for data reporting.ResultsOverall, 29 studies reported criminal justice costs and the costs of crime vary considerably.ConclusionsThis study illustrates possible touchpoints for cost inputs and outputs in the criminal justice pathway, providing a useful conceptualisation for better estimating criminal justice costs of injury in the future. However, better understanding of all criminal justice costs for injury-related crimes may provide justification for prevention efforts and potentially for groups who are disproportionately affected. Future research may focus on criminal justice cost estimates from injuries by demographics to better understand the impact these costs have on particular populations.
Technical and clinical outcomes in concurrent multivessel occlusions treated with mechanical thrombectomy: insights from the STAR collaboration
Authors: Saad Hassan , Eshraghi Sheila , Alawieh Ali M , Akbik Feras , Cawley C Michael , Howard Brian M , Ash Makenna , Hsu Alice , Pabaney Aqueel , Maier Ilko , Al Kasab Sami , El Naamani Kareem , Jabbour Pascal , Kim Joon-tae , Wolfe Stacey Q , Rai Ansaar , Starke Robert M , Psychogios Marios-Nikos , Shaban Amir , Arthur Adam S , Yoshimura Shinichi , Fragata Isabel , Cuellar-Saenz Hugo H , Polifka Adam J , Mascitelli Justin , Osbun Joshua W , Matouk Charles , Park Min S , Levitt Michael R , Dumont Travis M , Williamson Richard , Spiotta Alejandro M , Grossberg Jonathan A 
Published: December 2022

BackgroundEndovascular thrombectomy (EVT) has become the mainstay treatment for large vessel occlusion, with favorable safety and efficacy profile. However, the safety and efficacy of EVT in concurrent multi-territory occlusions (MTVOs) remains unclear.ObjectiveTo investigate the prevalence, clinical and technical outcomes of concurrent EVT for MTVOs.MethodsData were included from the Stroke Thrombectomy and Aneurysm Registry (STAR) with 32 stroke centers for EVT performed to treat bilateral anterior or concurrent anterior and posterior circulation occlusions between 2017 and 2021. Patients with MTVO were identified, and propensity score matching was used to compare this group with patients with occlusion in a single arterial territory.ResultsOf a total of 7723 patients who underwent EVT for acute ischemic stroke, 54 (0.7%) underwent EVT for MTVOs (mean age 69±12.5; female 50%). 28% had bilateral and 72% had anterior and posterior circulations occlusions. The rate of successful recanalization (Thrombolysis in Cerebral Infarction 2b/3), complications, modified Rankin score at 90 days, and mortality was not significantly different between the matched cohorts. Multivariate analysis confirmed that MTVOs were not associated with poor functional outcome, symptomatic intracranial hemorrhage, or longer procedure time.ConclusionCompared with EVT for single vessel occlusions, EVT in appropriately selected patients with MTVOs has a similar efficacy and safety profile.
Existence of solutions to uncertain differential equations of nonlocal type via an extended Krasnosel’skii fixed point theorem
Authors: Khastan Alireza , Nieto Juan J. , Rodríguez-López Rosana 
Published: December 2022

AbstractIn the present study, we investigate the existence of the solutions to a type of uncertain differential equations subject to nonlocal derivatives. The approach is based on the application of an extended Krasnosel’skii fixed point theorem valid on fuzzy metric spaces. With this theorem, we deduce that the problem of interest has a fuzzy solution, which is defined on a certain interval. Our approach includes the consideration of a related integral problem, to which the above-mentioned tools are applicable. We finish with some physical motivations.
Rich Extensions of the Core and the Equal Split Off Set
Authors: Yanovskaya Elena 
Published: December 2022

This paper studies extensions of the core and the equal split off set (ESOS) for TU games, and also subsolutions of the extensions in order to derive some new egalitarian solutions for TU games. Stability of the allocations is weakened such that an allocation [Formula: see text] can be blocked only by rich coalitions which together with a player will contain all players having payoffs not less than him. In accordance with such a definition of blocking, two new solutions — the rich core and the egalitarian rich core — are defined and characterized by means of weakening of axioms characterizing the ESOS on the class of all TU games [Dietzenbacher, B. and Yanovskaya, E. [2021] Consistency of the equal spit-off set, Int. J. Game Theory 50(1), 1–22]. Two subsolutions of the egalitarian rich core — the set of Lorenz undominated allocations and the set of allocations that lexicographically minimize maximal payoffs of players (Lmax solution) are characterized. The tight upper boundary of the number of allocations in the ESOS and in the egalitarian rich core is found.
Development Digitization In Enhancement Potency Tour Village Through Smart Village Concept in the Village Permis and Rajik South Bangka Regency
Authors: Julia Julia , Imainul Aprilian Rahil , Yanto Yanto 
Published: December 2022

Tourism is a sector that has the potential to be developed as a source of regional income, because in addition to providing benefits for the tourist attractions themselves, it also provides benefits to the supporting infrastructure, such as restaurants, lodging places, industrial centers, souvenir centers, etc.
Digitization of tourism is one of the important strategies in responding to the digital-oriented civilization of society in meeting their needs for traveling. Digitization of tourism is considered the right step in promoting tourism through a digital approach that has an impact on the development of tourism potential in a tourist village.
Based on the results of field observations, various problems were found in Permis and Rajik Villages, South Bangka Regency, namely the lack of efforts to publicize tourism potential in Permis and Rajik villages. Lack of knowledge of the village government regarding website creation.
Analysis of Risk Management Implementation in the Internal Audit Unit (SPI) Politeknik Pelayaran Surabaya Using Iso 31000:2018
Authors: Masita Ita , Yuhertiana Indrawati 
Published: December 2022

The application of risk management aims to minimize the probability and or consequences of unfavorable events as well as increase awareness of risk in strategic and operational decision making in an effort to achieve organizational goals. The Internal Audit Unit (SPI) Politeknik Pelayaran Surabaya is a supervisory unit formed to assist the implementation of Good University Governance by carrying out inspections or audits of all work units in the non-academic field.Risk treatment is required through risk management as the implementation of the management function in risk management at SPI Politeknik Pelayaran Surabaya. The risk management process uses a standard risk management process 31000 which consists of a context setting process, risk identification, risk analysis, risk evaluation, risk management, monitoring and review, and communication and consultation. This study uses a descriptive qualitative method with a case study at Internal Audit Unit (SPI) Politeknik Pelayaran Surabaya which describes and analyzes risk management using interview and documentation techniques in data collection. Data were analyzed using an interactive model, including data collection, data reduction, data presentation, and conclusions or verification. The final result of the risk management analysis of the internal audit unit (SPI) Politeknik Pelayaran Surabaya is a form of handling strategy in the implementation of internal control.
Teaching Amidst the Pandemic: Exploring the Perceptions and Experiences of Teachers in Remote Rural Municipalities in the Philippines
Authors: Legarde Michael Angelo A. , Sumandal Arman H. 
Published: December 2022

The world has been shaken by the advent of the COVID-19 pandemic, which has resulted in a dramatic loss of human life and poses an unprecedented challenge to almost all aspects of life, and the Philippines has not been an exception to these challenges. As a result, this deadly situation has flipped the offline teaching process and paved the way towards online-based teaching. This study was conducted to determine the perceptions and experiences of teachers in the remote areas towards online teaching. This study employed a cross-sectional explanatory research design and the analyses reveal that respondents with "high" technological proficiency are more likely to have a "positive" attitude toward online education whereas respondents with "poor" technological skills are more likely to have a "negative" attitude toward online learning. This strongly suggest that educational leaders may venture on training teachers on how to develop their technological knowledge and skills since it has a significant impact to their attitude towards online teaching. Moreover, further analysis also reveals that the relationship between teacher-respondents’ perceptions towards online teaching and their technological knowledge and skills was statistically significant. It is also recommended that training in online teaching needs to be provided to teachers to widen their understanding of online teaching.
Enhancement of the Performance of Junior High School Students using Numeracy Mobile Game on Operations of Integers
Authors: Lopez Lydia Marie R. 
Published: December 2022

This study aimed to evaluate and validate the developed numeracy mobile game to help improve the performance of junior high school students on the operations of integers in a public national high school in Antipolo City, the Philippines. The researcher used experimental and descriptive research designs in the study. The sources of data in this research were eighty (80) JHS students, twenty (20) from each grade level, from Old Boso-Boso National High School. Other respondents were the forty (40) teacher respondents consisting of twenty (20) experts and twenty (20) math teachers from Schools Division of Antipolo. The statistical tools used in this study were the frequency, percentage, weighted mean, independent-samples t-test, and paired t-test. It was revealed that there was no significant difference between the evaluations of the two groups of respondents on the developed numeracy mobile game in operations of integers in terms of game mechanics, visual aesthetic design, narrative design, incentive system, musical scores, and content and skills. It is recommended that the user interface of the game needs some enhancements like the controls for arrows up and down and improve the tutorial part before starting the real game or at the start of every level.
Clinical Utility of Short-Term Blood Pressure Measures to Inform Long-Term Blood Pressure Management
Authors: Wang Nelson , Harris Katie , Woodward Mark , Harrap Stephen , Mancia Giuseppe , Poulter Neil , Chalmers John , Rodgers Anthony ,   on behalf of the PROGRESS and ADVANCE collaborators
Published: December 2022

Background:
Decisions about hypertension management are substantially influenced by blood pressure (BP) levels measured before and soon after starting BP lowering drugs. We aimed to assess the utility of short-term BP changes in individuals in terms of long-term treatment response.

Methods:
Post hoc analyses of 2 randomized trials with 4-to-6 weeks active run-in for all participants, followed by randomization to active BP lowering treatment (combination perindopril±indapamide) or placebo. We categorized individuals by degree of systolic BP (SBP) change during active run-in treatment and assessed associations with subsequent postrandomization placebo-corrected BP reduction, cardiovascular events, and tolerability. We included individuals with baseline BP ≥140/90 mm Hg from the PROGRESS trial (Perindopril Protection Against Recurrent Stroke Study; 4275 individuals with cerebrovascular disease) and ADVANCE trial (The Action in Diabetes and Vascular Disease: Preterax and Diamicron-MR Controlled Evaluation; 6610 individuals with diabetes).

Results:

During the active run-in period, the proportion of participants with initial SBP changes in 4 categories (SBP increase, 0–9.9 mm Hg decrease, 10–19.9 mm Hg decrease, and ≥20 mm Hg decrease) were 17%, 27%, 28%, and 28% in PROGRESS and 21%, 22%, 24%, and 33% in ADVANCE. Randomization to active therapy achieved similar placebo-corrected long-term BP reductions across the 4 initial SBP change groups in both trials (
P
-values for heterogeneity >0.1). There was no significant difference in achieving BP <140/90 mm Hg at follow-up, major cardiovascular events, nor treatment tolerability according to the SBP change during active run-in period (all
P
-values >0.1).

Conclusions:
An individual’s apparent BP change immediately after commencing therapy has limited clinical utility. Therefore, more emphasis should be given to use of evidence-based regimens and measures over the long-term to ensure sustained BP control.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT00145925.
Wind-Forced Seasonal Exchange between Marginal Seas and the Open Ocean
Authors: Spall Michael A. 
Published: December 2022

Abstract
The circulation within marginal seas subject to periodic winds, and their exchange with the open ocean, are explored using idealized numerical models and theory. This is motivated by the strong seasonal cycle in winds over the Nordic Seas and the exchange with the subpolar North Atlantic Ocean through the Denmark Strait and Faroe Bank Channel. Two distinct regimes are identified: an interior with closed f/h contours and a shallow shelf region that connects to the open ocean. The interior develops a strong oscillating along-topography circulation with weaker ageostrophic radial flows. The relative importance of the bottom Ekman layer and interior ageostrophic flows depends only on ωh/Cd, where ω is the forcing frequency, h is the bottom depth, and Cd is a linear bottom drag coefficient. The dynamics on the shelf are controlled by the frictional decay of coastal waves over an along-shelf scale Ly = f0LsHs/Cd, where f0 is the Coriolis parameter, and Ls and Hs are the shelf width and depth. For Ly much less than the perimeter of the basin, the surface Ekman transport is provided primarily by overturning within the marginal sea and there is little exchange with the open ocean. For Ly on the order of the basin perimeter or larger, most of the Ekman transport is provided from outside the marginal sea with an opposite exchange through the deep part of the strait. This demonstrates a direct connection between the dynamics of coastal waves on the shelf and the exchange of deep waters through the strait, some of which is derived from below sill depth.

Significance Statement
The purpose of this study is to understand how winds over marginal seas, which are semienclosed bodies of water around the perimeter of ocean basins, can force an exchange of water, heat, salt, and other tracers through narrow straits between the marginal sea and the open ocean. Understanding this exchange is important because marginal seas are often regions of net heat, freshwater, and carbon exchange with the atmosphere. The present results identify a direct connection between processes along the coast of the marginal sea and the flow of waters through deep straits into the open ocean.
Siltuximab as a primary treatment for cytokine release syndrome in a patient receiving a bispecific antibody in a clinical trial setting
Authors: Lipe Brea C , Renaud Thomas 
Published: December 2022

Introduction Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are common toxicities associated with immunotherapies, including T cell redirecting bispecific antibodies. Although cooperative group guidelines recommend the use of tocilizumab or other IL-6/IL-6R inhibitors for the management of CRS and ICANS, reports on the use of siltuximab, an IL-6 inhibitor, for the treatment of CRS are limited. Case report We present the case of a 77-year-old male who received T cell redirecting bispecific antibody therapy with talquetamab for relapsed/refractory multiple myeloma (RRMM) and developed CRS with concurrent ICANS after receiving a second dose of talquetamab. Management and Outcome The patient received an infusion of siltuximab. The patient recovered from CRS within 1 h of siltuximab administration and ICANS within 7 h of siltuximab administration. Patient tolerated the subsequent dose of talquetamab with no evidence of CRS and continued on study. Discussion This case describes the successful use of siltuximab for the management of CRS in a patient treated with a T cell redirecting bispecific antibody for RRMM.