bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social networking and risk attitudes nexus: implication for technology adoption among smallholder cassava farmers in Ghana
Authors: Dadzie Samuel K. N. , Ndebugri Joseph , Inkoom Emmanuel W. , Akuamoah-Boateng Samuel 
Published: August 2022

Abstract
Background
Theoretically, social climate and social networking which may affect attitudes, motivations, and readiness towards quality improvement and rewards, influence the adoption decision process by possibly modifying the risk behaviour/attitudes of individuals. Thus for effective promotion of agricultural technologies among farmers in Africa, it is necessary to understand the social context within which risk attitudes are formed and social participation decisions are made. The study, therefore, employed the recursive bivariate endogenous switching probit model to examine how risk attitudes of farmers are shaped through social interactions in the information and communication networks of farmers to influence their technology adoption decisions. Here, the empirical application was done with the contextual case of agriculture intensification technologies in the Root and Tuber Improvement and Marketing Programme (RTIMP) introduced to smallholder cassava farmers in Ghana. This paper makes a contribution to recent advances in the empirical analysis of impact where anticipated problems posed by unobserved confounders are accounted for. This was possible since the approach used allows for the estimation of the treatment effect of endogenous risk attitude variable of interest on farmers’ adoption decisions.

Results
The study found that the effectiveness and usefulness of social interactions as well as a high degree of trust by cassava farmers in their social networks have higher tendencies to lower the degree of risk aversion behaviour of the farmers to significantly influence RTIMP Technologies adoption decisions positively. The ATE estimate confirms that there has been a significant increase of 38% probability in the likelihood of adopting agricultural intensification technologies in the RTIMP attributable to the non-risk aversion attitudes of cassava farmers. The cassava farmers’ risk attitudes were found to be significantly influenced by the effectiveness and usefulness of social interactions, and a high degree of trust as well as age, frequency of extension services, access to credit, and revenue.

Conclusion
By implication, attempts to introduce innovations to improve agricultural commodities value chains that target farmers must pay particular attention to the information and communication network to ensure the effectiveness and usefulness of information dissemination to farmers in an honest manner, so as to build trust; which will go a long way to reduce doubts and uncertainties (function of risk aversion). This will help achieve higher innovation adoption impacts thereby resulting in attaining the overall deliverable objectives of agricultural innovations.
Effect of the dietary supplementation with extracts of chestnut wood and grape pomace on performance and jejunum response in female and male broiler chickens at different ages
Authors: Pascual A. , Pauletto M. , Trocino A. , Birolo M. , Dacasto M. , Giantin M. , Bordignon F. , Ballarin C. , Bortoletti M. , Pillan G. , Xiccato G. 
Published: August 2022

Abstract
Background
Recently, interest in the use of herbs and phytogenic compounds has grown because of their potential role in the production and health of livestock animals. Among these compounds, several tannins have been tested in poultry, but those from chestnut wood and grape-industry byproducts have attracted remarkable interest. Thus, the present study aimed to gain further insights into the mechanisms involved in the response to the dietary supplementation with extracts of chestnut wood or grape pomace. To this purpose, 864 broiler chickens were fed a control diet (C) or the same diet supplemented 0.2% chestnut wood (CN) extract or 0.2% grape pomace (GP) extract from hatching until commercial slaughtering (at 45 days of age) to assess their effects on performance, meat quality, jejunum immune response and whole-transcriptome profiling in both sexes at different ages (15 and 35 d).

Results
Final live weight and daily weight gain significantly increased (P < 0.01) in chickens fed GP diets compared to CN and C diets. The villi height was lower in chickens fed the CN diet than in those fed the C diet (P < 0.001); moreover, a lower density of CD45+ cells was observed in chickens fed the CN diet (P < 0.05) compared to those fed the C and GP diets. Genes involved in either pro- or anti-inflammatory response pathways, and antimicrobial and antioxidant responses were affected by GP and CN diets. There was no effect of the dietary treatment on meat quality. Regarding sex, in addition to a lower growth performance, females showed a lower occurrence of wooden breast (16.7% vs. 55.6%; P < 0.001) and a higher occurrence of spaghetti meat (48.6% vs. 4.17%; P < 0.001) in pectoralis major muscles after slaughtering than those in males. Based on the results of whole-transcriptome profiling, a significant activation of some molecular pathways related to immunity was observed in males compared with those of females.

Conclusions
The GP supplementation improved chicken performance and promoted immune responses in the intestinal mucosa; moreover, age and sex were associated with the most relevant transcriptional changes.
Activity of erythrocyte antioxidant enzymes in healthy women depends on age, BMI, physical activity, and diet
Authors: Cecerska-Heryć Elżbieta , Krauze Klaudia , Szczęśniak Angelika , Goryniak-Mikołajczyk Aleksandra , Serwin Natalia , Śleboda-Taront Daria , Jacek Roksana , Heryć Rafał , Michalczyk Anna , Dołęgowska Barbara 
Published: August 2022

Abstract
Introduction
Antioxidant enzymes protect the human body against the harmful effects of oxidative stress. The activity of antioxidant enzymes changes with age and depends on dietary nutrients such as fats and vitamins, which can have a significant impact on minimizing or exacerbating oxidative stress.

Aim
To examine the effect of age, BMI, diet, physical activity, and smoking status on the activity of erythrocyte antioxidant enzymes catalase, glutathione reductase, glutathione peroxidase glutathione S-transferase, superoxide dismutase, and glutathione concentrations in healthy women.

Material and methods
This study included 98 healthy women aged between 20 and 65 years. All women underwent anthropometric tests: body weight, height, hip, and waist circumference. Antioxidant activity in erythrocytes was measured by spectrophotometric methods.

Results
Catalase activity increased significantly with age (p < 0.001), while superoxide dismutase activities and glutathione decreased with age (p = 0.008, p = 0.023, respectively). Women with a lower BMI (emaciation) had higher superoxide dismutase activity than those in the first degree of obesity (p = 0.009).

Conclusions
(1) Increased catalase activity with age may signify a large amount of hydrogen peroxide resulting from malfunctioning antioxidant systems in old age. (2) A decline in superoxide dismutase activity with age may indicate inactivation of this enzyme, inappropriate SOD function in the presence of excessive amounts of hydrogen peroxide, and glycation of superoxide dismutase molecules. (3) A negative correlation between superoxide dismutase activity and the BMI index may indicate a decreased enzymatic activity in obese people.
Assessing digital competence and its relationship with the socioeconomic level of Chilean university students
Authors: Silva-Quiroz Juan , Morales-Morgado Erla Mariela 
Published: August 2022

AbstractDigital competence (DC) is one of the key aspects in citizen development in the digital age. The DC is particularly important in forming university students and future teachers. This article presents the main results of a study to evaluate DC and its relationship with the socioeconomic level of first-year students of pedagogy in three Chilean public universities, located in the north, center, and south of the country. A quantitative research methodology was used, with a sample of 817 students, the data were collected through the DIGCOMP-PED evaluation instrument, which evaluates DC development using the DIGCOMP framework. The results were analyzed at the general and socioeconomic level on the variables of the educational establishment where they attended high school and the territorial area of the university they attended. The main results indicate that the level of DC achievement is intermediate, the areas with the highest levels of achievement were “network security” and “online communication and collaboration.” On the other hand, the lowest levels of achievement were reached in the areas “information and digital literacy,” “digital content creation,” and “problem solving.” The level of DC is higher among students of private establishments and those who attend universities located in the central area.
Examining enablers of vaccine hesitancy toward routine childhood and adolescent vaccination in Malawi
Authors: Adeyanju Gbadebo Collins , Betsch Cornelia , Adamu Abdu A. , Gumbi Khadijah Sanusi , Head Michael G. , Aplogan Aristide , Tall Haoua , Essoh Tene-Alima 
Published: August 2022

Abstract
Background
The contribution of vaccination to global public health and community wellbeing has been described as one of the greatest success stories of modern medicine. However, 13.5 million children still miss at least one of their routine vaccinations, and this contributes to about 1.5 million deaths from vaccine-preventable diseases. One of the contributing factors has been associated with vaccine hesitancy. Vaccine hesitancy is the delay or refusal of vaccines despite their availability. The study explored factors from multiple perspectives that influence hesitancy among caregivers of children and adolescent girls eligible for childhood routine immunisation and the Human Papillomavirus vaccine in Malawi.

Methods
The methodology used was qualitative such as key informant interviews and focus-group discussion. Information was obtained from caregivers, community and religious leaders, leaders of civil society groups, teachers in schools where Human Papillomavirus vaccine were piloted, healthcare workers, national and district-level officials of the expanded program on immunisation. There were 25 key informant interviews and two focus-group discussions, with 13 participants. The study was conducted between April to May 2020. The Interviews and discussions were audio-recorded, transcribed, and analysed using a thematic content approach.

Results
Most vaccine-hesitancy drivers for routine immunisation were also relevant for the HPV vaccine. The drivers included inadequate awareness of the vaccination schedule, rumours and conspiracy theories exacerbated by religious beliefs, low literacy levels of caregivers, distance and transport to the vaccination clinic, gender role and a disconnect between community healthcare workers and community leaders.

Conclusions
The study demonstrated that a network of factors determines vaccine hesitancy for childhood Routine Immunisation and Human Papillomavirus, and some of them are interrelated with one another. This has implications both for current levels of vaccine acceptance and the introduction of any new vaccine, such as those against Malaria, HIV/AIDS, HPV or COVID-19 (coronavirus disease 2019). Therefore, strategies developed to address vaccine hesitancy must be multi-component and wide-ranging.
Eublemma scitula (Rambur) (Lepidoptera: Erebidae): first evidence of a predator of the invasive barnacle scale, Ceroplastes cirripediformis comstock (Hemiptera: Coccidae)
Authors: Gaikwad Mahesh B. , Kedar Santosh C. , Kalyani Dayanand C. , Shashank Pathour R. 
Published: August 2022

Abstract
Background
The invasive barnacle scale, Ceroplastes cirripediformis Comstock (Hemiptera: Coccidae), is a pest native to South America and the Caribbean islands that has recently emerged as a serious threat to agricultural, horticultural, ornamental, medicinal, and aromatic plants. Finding indigenous natural enemies to control the invasive pests is the first step for developing a biological control program.

Results
The present study reports Eublemma scitula (Rambur) (Lepidoptera: Erebidae) for the first time as a predator of C. cirripediformis in India. The identity of E. scitula was confirmed morphologically based on male genitalia and mitochondrial cytochrome oxidase I (mt COI) gene sequences. E. scitula larvae were found as dominant predators of C. cirripediformis. The predatory activity of E. scitula was observed from June to September, with its peak population recorded during mid-July (2.1 larvae per 25 cm of infested shoot).

Conclusion
This is the first global record of E. scitula predating on an invasive barnacle scale insects from India. Furthermore, studies on the feeding potential of E. scitula under controlled and field conditions need to be evaluated for utilizing them as a biocontrol agent against C. cirripediformis.
Characterization and pathogenicity of Beauveria bassiana strains isolated from Galleria mellonella L. (Lepidoptera: Pyralidae) in Turkey
Authors: Gençer Dönüş , Bayramoğlu Zeynep 
Published: August 2022

Abstract
Background
The greater wax moth, Galleria mellonella L. (Lepidoptera: Pyralidae), is among the most important wax pests economically. In the larval stage, the pest feeds on honeycomb wax and seriously damages the combs that were left unattended by the bees. Recently, the interest in ecologically safer alternatives to chemical insecticides has increased due to the significant success achieved with entomopathogenic microorganisms in the control of several lepidopteran pest larvae with minimum or no harm to the bees, natural rivals, animals, and humans. The current study was conducted to investigate the pathogenicity of two entomopathogenic fungus isolates (Beauveria bassiana G-A and G-B) isolated from dead G. mellonella larvae and their efficacy in pest control under laboratory conditions.

Results
Morphological and molecular identification revealed that the two isolates corresponded to B. bassiana species G-A and G-B strains. The response to the inoculation with the two fungal strains was conducted on G. mellonella larvae at 1 × 105–9 conidia/ml concentrations. The concentrations led to 96.54 and 89.66% mortality in G-A and G-B B. bassiana isolates at the highest concentration on day 10, respectively. LC50 was calculated between 0.2 × 106 (0.03 – 1.6) and 0.6 × 106 (0.07 – 6.1) conidia/ml.

Conclusion
The present study findings demonstrated that these isolates had the potential for G. mellonella control and B. bassiana isolates were a safe alternative to chemical control and could be recommended for use to protect stored wax products.
Delivering transcutaneous auricular neurostimulation (tAN) to improve symptoms associated with opioid withdrawal: results from a prospective clinical trial
Authors: Tirado Carlos F. , Washburn Stephanie N. , Covalin Alejandro , Hedenberg Caroline , Vanderpool Heather , Benner Caroline , Powell Daniel P. , McWade Melanie A. , Khodaparast Navid 
Published: August 2022

Abstract
Background
As pharmacological treatments are the primary option for opioid use disorder, neuromodulation has recently demonstrated efficacy in managing opioid withdrawal syndrome (OWS). This study investigated the safety and effectiveness of transcutaneous auricular neurostimulation (tAN) for managing OWS.

Methods
This prospective inpatient trial included a 30-minute randomized, sham-controlled, double-blind period followed by a 5-day open-label period. Adults with physical dependence on opioids were randomized to receive active or sham tAN following abrupt opioid discontinuation. The Clinical Opiate Withdrawal Scale (COWS) was used to determine withdrawal level, and participants were required to have a baseline COWS score ≥ 13 before enrollment. The double-blind period of the study occurred during the first 30-minutes to assess the acute effects of tAN therapy compared to a sham control. Group 1 received active tAN during both the 30-minute double-blind period and the 5-day open-label period. Group 2 received passive sham tAN (no stimulation) during the double-blind period, followed by active tAN during the 5-day open-label period. The primary outcome was change in COWS from baseline to 60-minutes of active tAN (pooled across groups, accounting for 30-minute delay). Secondary outcomes included difference in change in COWS scores between groups after 30-minutes of active or sham tAN, change in COWS scores after 120-minutes of active tAN, and change in COWS scores on Days 2–5. Non-opioid comfort medications were administered during the trial.

Results
Across all thirty-one participants, the mean (SD) COWS scores relative to baseline were reduced by 7.0 (4.7) points after 60-minutes of active tAN across both groups (p < 0.0001; Cohen’s d = 2.0), demonstrating a significant and clinically meaningful reduction of 45.9%. After 30-minutes of active tAN (Group 1) or sham tAN (Group 2), the active tAN group demonstrated a significantly greater COWS score reduction than the sham tAN group (41.7% vs. 24.1%; p = 0.036). Participants across both groups achieved an average COWS reduction up to 74.7% on Days 2–5.

Conclusion
Results demonstrate tAN is a safe and effective non-opioid approach for reducing symptoms of OWS. This study supported an FDA clearance.

Clinical trial registration
clinicaltrials.gov/ct2/show/NCT04075214, Identifier: NCT04075214, Release Date: August 28, 2019.
Worse outcome of debridement, antibiotics, and implant retention in acute hematogenous infections than in postsurgical infections after total knee arthroplasty: a multicenter study
Authors: Chang Moon Jong , Ro Du Hyun , Kim Tae Woo , Lee Yong Seuk , Han Hyuk-Soo , Chang Chong Bum , Kang Seung-Baik , Lee Myung Chul 
Published: August 2022

Abstract
Background
We sought to determine (1) the success rate of debridement, antibiotics, and implant retention (DAIR) for acute periprosthetic joint infection (PJI) of the knee in patients with acute postsurgical infection and in those with acute hematogenous infection via a multicenter study, (2) the factors related to the failure of DAIR for overall acute PJI and acute hematogenous PJI via subgroup analysis, and (3) whether the PJI recurrence patterns differed between the two groups over time after DAIR.

Methods
This retrospective multicenter study included 101 acute knee PJI. Acute postsurgical PJI was defined as PJI diagnosed < 3 months following initial knee arthroplasty surgery. DAIR was performed for 34 cases of acute postsurgical PJIs (postsurgical group) and 67 cases of acute hematogenous PJIs (hematogenous group). The success rates between groups were compared, and factors related to DAIR failure were analyzed.

Results
The overall success rate of DAIR was 77%. The success rate tended to be higher in the postsurgical group than in the hematogenous group (p = 0.060). However, there was no significant factor related to DAIR failure in the subgroup analysis of acute hematogenous PJIs. In the postsurgical group, the recurrence of PJI occurred until 3 months, whereas in the hematogenous group, recurrence occurred for up to 2 years.

Conclusions
The failure rate tended to be higher in the acute hematogenous PJI group than in the acute postsurgical PJI group. Since acute hematogenous infections may recur for a longer period than postsurgical infections, careful follow-up is required after DAIR.
Implementation strategy mapping methods to improve autism intervention use in community settings: a study protocol
Authors: Sridhar Aksheya , Drahota Amy , Tschida Jessica E. 
Published: August 2022

Abstract
Background
Implementation strategies are purported to facilitate adoption and use of evidence-based practices (EBPs) across settings. The use of tailored implementation strategies may be particularly effective, as they are selected with the explicit purpose of addressing setting-specific implementation determinants. However, methods to select and tailor implementation strategies, including in community settings, remain understudied. This project will identify and describe implementation strategy mapping methods (ISMMs) from extant peer-reviewed literature and pilot test a method to match implementation strategies with determinants in low-resourced community mental health (CMH) agencies that deliver services to children on the autism spectrum.

Methods
Aim 1: A scoping review, following PRISMA guidelines, will be conducted to identify implementation strategy mapping methods (ISMMs) utilized in child mental health settings. Data extraction will identify and describe each ISMM, including identifying methodological and procedural steps, analyzing the frequency of ISMM use, and identifying outcomes measured in eligible ISMM studies.
Aim 2: Using scoping review findings, select and pilot test one ISMM within five community mental health agencies in Michigan that provide services to autistic children. We will recruit five directors/agency leaders, supervisors, and direct providers at each of the eligible agencies (expected N = 25). A sequential explanatory (QUAN➔ QUAL) mixed methods design will be used. Participants will complete a demographics and client survey, as well as a needs assessment to identify implementation determinants. The impact of the ISMM on organizational readiness for change (from pre- to post-ISMM), as well as implementation outcomes of the ISMM (feasibility, acceptability, appropriateness, usability), will be examined. Semi-structured interviews will elicit stakeholder perspectives on the mapping method.

Discussion
The current project aims to advance our knowledge of methods for selecting, tailoring, and mapping implementation strategies to address context-specific determinants to implementation. Additionally, this project will contribute to growing science found at the intersection of implementation science and autism research by utilizing the implementation determinants framework, the CFIR, to guide data collection, analysis, and interpretation of findings. Finally, these findings may support future EBP implementation efforts within low-resourced communities, with the ultimate goal of increasing equity in access to EBPs for autistic children.