bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of Thrombus Aspiration for Patients With Acute Coronary Syndrome: Insights From the Nationwide J‐PCI Registry
Authors: Inohara Taku , Kohsaka Shun , Yamaji Kyohei , Iida Osamu , Shinke Toshiro , Sakakura Kenichi , Ishii Hideki , Amano Tetsuya , Ikari Yuji 
Published: August 2022

Background
There is significant regional or institutional variation in the use of thrombus aspiration (TA) in patients undergoing percutaneous coronary intervention (PCI). We investigated the temporal trend in TA use and its association with clinical outcomes in acute coronary syndrome using the nationwide J‐PCI (Japanese PCI) registry.

Methods and Results

Between 2016 and 2018, patients with acute coronary syndrome undergoing PCI (n=282 606; median age, 71.0 years; interquartile range, 62.0–79.0 years; women, 24.7%) at 1124 hospitals were stratified on the basis of whether TA was performed (TA and non‐TA). The patients were subdivided according to clinical presentation (ST‐segment–elevation myocardial infarction, non–ST‐segment–elevation myocardial infarction, and unstable angina). Successful PCI, defined as the achievement of TIMI (Thrombolysis in Myocardial Infarction) 3 flow, and in‐hospital mortality were assessed. During the study period, 83 422 patients (29.5%) underwent TA (52.9%, 23.5%, and 5.2% for ST‐segment–elevation myocardial infarction, non–ST‐segment–elevation myocardial infarction, and unstable angina, respectively), and the TA implementation rate remained relatively stable throughout. Patients treated with TA had higher rate of successful PCI than non‐TA (98.7% versus 97.8%;
P
<0.001). TA was not associated with in‐hospital death among patients with ST‐segment–elevation myocardial infarction (adjusted odds ratio [aOR], 1.02 [95% CI, 0.94–1.12]). However, TA use was associated with higher rates of in‐hospital death in patients with non–ST‐segment–elevation myocardial infarction ( aOR, 1.51 [95% CI, 1.23–1.86]) or unstable angina ( aOR, 1.95 [95% CI, 1.37–2.79]).

Conclusions
In our retrospective analysis of the nationwide PCI registry, TA use was associated with a higher achievement of successful PCI without impairing in‐hospital mortality among patients with ST‐segment–elevation myocardial infarction. Nevertheless, its use should be cautioned in less‐established indications (eg, non–ST‐segment–elevation myocardial infarction and unstable angina).
Fuzzy-Constrained Graph Pattern Matching in Medical Knowledge
Graphs
Authors: Li Lei , Du Xun , Zhang Zan , Tao Zhenchao 
Published: August 2022

Abstract
The research on graph pattern matching (GPM) has attracted a lot of attention. However, most of the research has focused on complex networks, and there are few researches on GPM in the medical field. Hence, with GPM this paper is to make a breast cancer-oriented diagnosis before the surgery. Technically, this paper has firstly made a new definition of GPM, aiming to explore the GPM in the medical field, especially in Medical Knowledge Graphs (MKGs). Then, in the specific matching process, this paper introduces fuzzy calculation, and proposes a multi-threaded bidirectional routing exploration (M-TBRE) algorithm based on depth first search and a two-way routing matching algorithm based on multi-threading. In addition, fuzzy constraints are introduced in the M-TBRE algorithm, which leads to the Fuzzy-M-TBRE algorithm. The experimental results on the two datasets show that compared with existing algorithms, our proposed algorithm is more efficient and effective.
FAIR Data Point: A FAIR-Oriented Approach for Metadata Publication
Authors: da Silva Santos Luiz Olavo Bonino , Burger Kees , Kaliyaperumal Rajaram , Wilkinson Mark D. 
Published: August 2022

ABSTRACTMetadata, data about other digital objects, play an important role in FAIR with a direct relation to all FAIR principles. In this paper we present and discuss the FAIR Data Point (FDP), a software architecture aiming to define a common approach to publish semantically-rich and machine-actionable metadata according to the FAIR principles. We present the core components and features of the FDP, its approach to metadata provision, the criteria to evaluate whether an application adheres to the FDP specifications and the service to register, index and allow users to search for metadata content of available FDPs.
Emigrate out of National Borders, Immigrate into Diasporic Spaces
Authors: Phan Anh Ngoc Quynh 
Published: August 2022

Abstract
The article explores the ways in which Vietnamese international doctoral students participated in and influenced social spaces to produce diasporic subjectivity among Vietnamese diasporic communities in the study countries, and how this diasporic subjectivity was produced in what I term ‘diasporised moments’. Guided by theory of space, I look at how Vietnamese doctoral students negotiated their ‘membership’ of those communities, how their national identity was challenged and contested, and how their nostalgia was triggered against the backdrop of their transnational life, leading to their diasporic subjectivity in the making. I argue that the theoretical bearings of space allow us to expand our understanding of the integration of international students into life on foreign soil beyond the common assumption of integration into the local culture only. I further argue that international students do not purely experience homesickness but actually produce diasporic subjectivity in their temporary migration for academic pursuits.
Death, Demise, and the Decline of Prophecy
Authors: Lester Olivia Stewart 
Published: August 2022

Abstract
This article examines Apollo’s prophecy at Delphi as well as prophecy in ancient Judaism and ancient Christianity in light of recent scholarship on the demise of religions. I argue that two questions remain about ancient narratives of decline amidst the scholarship on the death of religions. First, how should scholars engage ancient narratives of decline that threaten to erase other practices, beliefs, and rhetoric? Second, what about the challenges of defining a ‘religion’ that declines? Brent Nongbri has suggested that categories other than religion may provide more fruitful avenues for describing antiquity; I argue that prophecy is one such category.
Revisiting the Death/s of Religions
Authors: van den Heever Gerhard 
Published: August 2022

Abstract
This essay responds to the essays comprising the theme issue, Do Religions Die? Theorising Death and Demise of Greek and Roman Religions. Reviewing various case studies and theoretical introductory essays of the volume, The Demise of Religion, and the special issue of Numen 68, no. 2&3 (2021), I argue that at stake are two desiderata: the first relates to defining religion (what counts as religion?), and the second relates to the historiography of the history of religions (who narrates the story of religion deaths, from which perspective, and with what rhetorical purpose?). It is shown how definition of religion and critical historiography in tandem enable an approach from the perspective of discourse theory. From this perspective it is possible to describe, explain, and theorise ‘religion deaths’ as shifts in culture, migration patterns and social formations, concomitant changes in religious formations, yet with continuity in functionalities.
Rethinking Power and Forestry Governance in Colonial and Post-Colonial Tanzania: Towards a Poststructural Political Ecology
Authors: Mukono Danstan 
Published: August 2022

Abstract
There is an emerging scholarly concern for reconstructing and engaging with diverse approaches that theorize the question of power. Scholars focusing on the Global South critically explore how power dynamics shaping forestry governances hold western colonial assumptions that erase complexities of nature-society relations. Yet, many studies have not systematically (re)conceptualized issues of knowledge-power nexus as an instrument of control and power through Foucauldian and coloniality lens in Tanzania. The review critically discusses politics and power by plotting it within environmentality and coloniality literature. It argues that postcolonial forestry governance is devoid of its colonial residue that seems to be visible in the current forestry governance regimes. It proposes an alternative critical constructivist approach that considers the role of knowledge production through which forest discourses as assemblages of power mechanisms are crucial in producing uneven social and ecological implications.
Education Philosophy of Pragmatism and its Impact in the Global Context Present
Authors: Dung Bui Xuan , Pham Kien Thi 
Published: August 2022

Abstract
Educational philosophy helps to orient the educational development process of each country and develop the capacity of each individual in society. In the educational history of each country, there is always a process of preserving and transferring social heritages. The educational system prepares the next generation to enter society and imparts ideas, values, and beliefs that will shape young people’s thinking and behavior for the rest of their lives. Therefore, this article wishes to clearly and vividly clarify the importance of studying Pragmatism’s educational philosophy to realize its present influence. At the same time, it is crucial to deeply understand the educational process of Pragmatism to derive meaning and clarify the primary function of educating Vietnamese people in the context of current global integration. The article uses the materialist dialectic method with broad and specific historical principles to evaluate Vietnamese education with opportunities and challenges in the current integration process by studying Pragmatism’s philosophical education. The article found that the theory of education by Pragmatism clarifies the role of social educational institutions – schools in the educational process. In parallel, it is a teacher with educational methods and programs that are the basis for educating learners to become comprehensive citizens in the future. And students are the goal and the product that the educational philosophy needs to implement. Research results, the article clarifies the need to develop an educational philosophy for Vietnamese people to build comprehensively in the socialist orientation in the current globalization context.
Molecular phylogenetics and tribal classification of Japanese Pyraustinae and Spilomelinae (Lepidoptera: Crambidae)
Authors: Matsui Yuki , Mally Richard , Kohama Sari , Aoki Itsuzai , Azuma Masaaki , Naka Hideshi 
Published: August 2022

Abstract
Two of the largest subfamilies of Crambidae, Pyraustinae and Spilomelinae, have 341 species recorded in Japan, but their natural relationships are poorly understood. We reconstructed a molecular phylogeny based on one mitochondrial (COI) and three nuclear genes (CAD, EF1-α, RpS5) for 129 species in 69 genera of Spilomelinae and 62 species in 27 genera of Pyraustinae from Japan. The concatenated data was analyzed by maximum likelihood and Bayesian inference methods. Our results recovered most tribes recognized in a previous study, but Pyraustini is paraphyletic as it includes Portentomorphini, and the paraphyletic Nomophilini comprise Trichaeini. The species-rich Spilomelinae genera Patania, Nacoleia, Glyphodes, and Syllepte are polyphyletic and need thorough revision. In Pyraustinae, a “Monocotyledon-clade” and Anania sensu lato were recognized for the first time. Based on phylogenetic results and morphological investigations, we propose six taxonomic changes, including the transfer of Acropentias from Spilomelinae to Lathrotelinae and Mabra from Spilomelinae to Pyraustinae. Fourteen unplaced genera of Spilomelinae and two of Pyraustinae are newly assigned to tribes.
Historizität im biblischen Schulactus
Authors: Blum Stephanie 
Published: August 2022

Abstract
Johann Klaj’s Engel⸗ und Drachen⸗Streit (1649) takes an intermediate position in his literary work between the depiction of war and peace poetry: in this ‘Schulactus’, a biblical subject is combined with the historical context of the recently ended Thirty Years War and used for an eschatological interpretation of war. At the same time, the ‘Schulactus’ performs a secular transfer of these interpretive patterns in the context of the peace ceremonies, which is due to the representative functions of his recitational practice, revealing the institutional as well as politico-religious integration of literature. Examining the text, paratext and the historical context of presentation, this contribution elaborates how knowledge is created, transmitted and represented as well as combined with a negotiation of power in discourses and practices of the early modern period.
Behind Enemy Lines: An Account of a Secret Conversion to Shiism in Sixteenth-Century Ottoman Aleppo
Authors: Stewart Devin J. 
Published: August 2022

Abstract
This study examines a work by Ḥusayn b. ʿAbd al-Ṣamad al-ʿĀmilī (918–984/1512–1576) in which he provides the supposed transcript of a private debate he held with a Ḥanafī jurist in Aleppo in 951/1544–45. In it, Ḥusayn claims to have converted his Sunni acquaintance to Shiite Islam through skilled argument and adduction of proof. It is argued here that he modified what may originally have been a debate on the relative merits of the Shāfiʿī and Ḥanafī legal schools to focus on Sunni-Shiite polemics, including the relative merits of the Jaʿfarī legal school and the status of the Companions of the Prophet. He probably recorded the debate in 961–63/1554–56, shortly after his arrival in Safavid territory, in an attempt to curry favour with and attract the patronage of Shah Tahmasb or other Safavid officials.
The Language Shift of Taiwanese Hokkien and Hakka in Hsinchu County and Hsinchu City, Taiwan: A Data Comparison of the Surveys of 1978 and 2015
Authors: Chen Shu-chuan 
Published: August 2022

Abstract
This study examines the extent to which language shift occurred in the Minnan and Hakka areas of Hsinchu, Taiwan, by comparing Marinus van den Berg’s findings (1986) with our own more recent observations. In 1978, van den Berg found that customers in the Minnan area used Taiwan Mandarin more than customers in the Hakka area during business transactions. Our observations in 2015 had the opposite results, with Taiwan Mandarin being spoken more in the Hakka area than in the Minnan area. The reason for this change is seen to be the expansion of people’s living environment, reducing the opportunities for Hakka people to speak their own language when encountering people of other ethnicities. Additionally, as a minority, the Hakka people were more sensitive towards language use, that is, were likely to use high-level languages or standard languages that were more valued by society.
Improving Healthcare Practice Through the Implementation of Human Factors and Ergonomics Principles
Authors: Bitan Yuval , Sasangohar Farzan 
Published: August 2022

Objective Present a collection of papers focusing on improving healthcare practice through the implementation of human factors and ergonomics principles that were presented at the International Ergonomics Association (IEA) 2021 international conference. Background The mission of the IEA is to elaborate and advance ergonomics science and practice and to expand its scope of application. Method We reviewed papers that were submitted for presentation at the IEA 2021 international conference and focused on improving healthcare practice through the implementation of human factors and ergonomics principles. Results The eight papers that are included in this special issue cover varied aspects of human factors application and implementation. Conclusion This special issue provides clear evidence that the science of human factors is relevant and is continuing to grow and so is its implementation in healthcare. Application This special issue offers a selection of applied works, providing a wide scope of human factors guidelines, methods, and theories in healthcare work environments.
Integrating Maternal Depression Screening Into an Early Intervention Program: An Implementation Evaluation
Authors: Salomon Rebecca E. , Waldrop Julee B. , Baker Maureen , Mandel Marcia A. , LaForett Doré R. , Beeber Linda S. 
Published: August 2022

Background: In all 50 states, early intervention (EI) services to improve long-term child cognitive and academic outcomes are provided to infants and toddlers with suspected or diagnosed developmental delays. When mothers of EI-enrolled children experience depressive symptoms, uptake of EI services can be compromised. Aims: The purpose of the article is to present a depressive symptom screening intervention for mothers consisting of toolkit development for EI staff and families, symptom screening for mothers and follow-up protocol. To formally evaluate the implementation of the intervention, our research team followed the consolidated framework for implementation research (CFIR). Methods: Participants were 12 EI service coordinators across two offices. Focus groups and individual interviews were used to develop the toolkit and education module. Through the five CFIR domains, we evaluated the implemented intervention in order to allow other teams to learn from our experiences. Results: Our team successfully partnered with SCs to develop the intended deliverables. Still, the SCs found it challenging to conduct the screenings and reported mixed success. Conclusions: Preparation of EI SCs to integrate mental health screenings into their existing skillsets requires a high level of support from the research team, resulting in a rich understanding of the barriers—and potential rewards—for staff and families.
Disseminated Mycobacterium avium infection in a cat on long-term ciclosporin therapy and potential latent infection of an in-contact cat
Authors: Webster Jade , Marchesi Francesco , Gunn-Moore Danièlle , Haining Hayley , Ridyard Alison E 
Published: August 2022

Case summary An 8-year-old domestic shorthair cat receiving long-term ciclosporin treatment was evaluated for a history of weight loss and hyporexia. The main clinical finding was a cluster of enlarged mesenteric lymph nodes. Cytological examination of fine-needle aspirates showed granulomatous inflammation with abundant acid-fast bacilli. A diagnosis of Mycobacterium avium complex (MAC) infection was confirmed by PCR. The cat’s clinical condition deteriorated rapidly despite appropriate antibiotic treatment and it was euthanased 2 weeks after initial presentation due to development of severe paraparesis and ataxia. Post-mortem examination revealed granulomatous inflammation affecting multiple lymph nodes and other organs with intrahistiocytic acid-fast bacilli consistent with mycobacteria when stained using Ziehl–Neelsen stain. Another cat in the same household was screened for infection using the interferon gamma release assay (IGRA), with the result being consistent with infection by non-tuberculous mycobacteria (NTM), which includes MAC; however, it had no grossly detectable disease. Relevance and novel information This case report is an unusual presentation of disseminated MAC infection in a cat, which remains a rare diagnosis. Clinicians should be aware of unusual and rare presentations of this infection. The clinical findings, progression of disease and histopathology results add to the current clinical database for feline disseminated MAC infections. Another cat in the same household tested positive for NTM by IGRA without any gross disease. This was suggestive of latent MAC infection which, to our knowledge, has not been previously reported in an in-contact cat.
Targets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study
Authors: Oleshko Olga , Werwitzke Sonja , Klingberg Annika , Witte Torsten , Eichler Hermann , Klamroth Robert , Holstein Katharina , Hart Christina , Pfrepper Christian , Knöbl Paul , Greil Richard , Neumeister Peter , Reipert Birgit M. , Tiede Andreas 
Published: August 2022

Abstract
The root cause of autoantibody formation against factor VIII (FVIII) in acquired hemophilia A (AHA) remains unclear. We aimed to assess whether AHA is exclusively associated with autoantibodies toward FVIII or whether patients also produce increased levels of autoantibodies against other targets. A case-control study was performed enrolling patients with AHA and age-matched controls. Human epithelial cell (HEp-2) immunofluorescence was applied to screen for antinuclear (ANA) and anticytoplasmic autoantibodies. Screening for autoantibodies against extractable nuclear antigens was performed by enzyme immunoassay detecting SS-A/Ro, SS-B/La, U1RNP, Scl-70, Jo-1, centromere B, Sm, double-stranded DNA, and α-fodrin (AF). Patients with AHA were more often positive for ANA than control patients (64% vs 30%; odds ratio [OR] 4.02, 1.98-8.18) and had higher ANA titers detected than controls. Cytoplasmic autoantibodies and anti-AF immunoglobulin A autoantibodies were also more frequent in patients with AHA compared with controls. Autoantibodies against any target other than FVIII were found in 78% of patients with AHA compared with 46% of controls (OR 4.16, 1.98-8.39). Results were similar preforming sensitivity analyses (excluding either subjects with autoimmune disorders, cancer, pregnancy, or immunosuppressive medication at baseline) and in multivariable binary logistic regression. To exclude that autoantibody staining was merely a result of cross-reactivity of anti-FVIII autoantibodies, we tested a mix of 7 well-characterized monoclonal anti-FVIII antibodies. These antibodies did not stain HEp-2 cells used for ANA detection. In conclusion, a diverse pattern of autoantibodies is associated with AHA, suggesting that a more general breakdown of immune tolerance might be involved in its pathology.
Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations
Authors: Ren Jingjing , Qu Rihao , Rahman Nur-Taz , Lewis Julia M. , King Amber Loren Ong , Liao Xiaofeng , Mirza Fatima N. , Carlson Kacie R. , Huang Yaqing , Gigante Scott , Evans Benjamin , Rajendran Barani Kumar , Xu Suzanne , Wang Guilin , Foss Francine M. , Damsky William , Kluger Yuval , Krishnaswamy Smita , Girardi Michael 
Published: August 2022

AbstractThe incidence of cutaneous T-cell lymphoma (CTCL) increases with age, and blood involvement portends a worse prognosis. To advance our understanding of the development of CTCL and identify potential therapeutic targets, we performed integrative analyses of paired single-cell RNA and T-cell receptor (TCR) sequencing of peripheral blood CD4+ T cells from patients with CTCL to reveal disease-unifying features. The malignant CD4+ T cells of CTCL showed highly diverse transcriptomic profiles across patients, with most displaying a mature Th2 differentiation and T-cell exhaustion phenotype. TCR-CDR3 peptide prediction analysis suggested limited diversity between CTCL samples, consistent with a role for a common antigenic stimulus. Potential of heat diffusion for affinity-based trajectory embedding transition analysis identified putative precancerous circulating populations characterized by an intermediate stage of gene expression and mutation level between the normal CD4+ T cells and malignant CTCL cells. We further revealed the therapeutic potential of targeting CD82 and JAK that endow the malignant CTCL cells with survival and proliferation advantages.