bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influenza Vaccination Among Pregnant Women: Self-report Compared With Vaccination Data From Electronic Health Records, 2018-2020 Influenza Seasons
Authors: Daley Matthew F. , Reifler Liza M. , Shoup Jo Ann , Glanz Jason M. , Naleway Allison L. , Jackson Michael L. , Hambidge Simon J. , McLean Huong , Kharbanda Elyse O. , Klein Nicola P. , Lewin Bruno J. , Weintraub Eric S. , McNeil Michael M. , Razzaghi Hilda , Singleton James A. 
Published: June 2022

Objectives: Having accurate influenza vaccination coverage estimates can guide public health activities. The objectives of this study were to (1) validate the accuracy of electronic health record (EHR)–based influenza vaccination data among pregnant women compared with survey self-report and (2) assess whether survey respondents differed from survey nonrespondents by demographic characteristics and EHR-based vaccination status. Methods: This study was conducted in the Vaccine Safety Datalink, a network of 8 large medical care organizations in the United States. Using EHR data, we identified all women pregnant during the 2018-2019 or 2019-2020 influenza seasons. Surveys were conducted among samples of women who did and did not appear vaccinated for influenza according to EHR data. Separate surveys were conducted after each influenza season, and respondents reported their influenza vaccination status. Analyses accounted for the stratified design, sampling probability, and response probability. Results: The survey response rate was 50.5% (630 of 1247) for 2018-2019 and 41.2% (721 of 1748) for 2019-2020. In multivariable analyses combining both survey years, non-Hispanic Black pregnant women had 3.80 (95% CI, 2.13-6.74) times the adjusted odds of survey nonresponse; odds of nonresponse were also higher for Hispanic pregnant women and women who had not received (per EHR data) influenza vaccine during current or prior influenza seasons. The sensitivity, specificity, and positive predictive value of EHR documentation of influenza vaccination compared with self-report were ≥92% for both survey years combined. The negative predictive value of EHR-based influenza vaccine status was 80.5% (95% CI, 76.7%-84.0%). Conclusions: EHR-based influenza vaccination data among pregnant women were generally concordant with self-report. New data sources and novel approaches to mitigating nonresponse bias may be needed to enhance influenza vaccination surveillance efforts.
Association between anticoagulant therapy, exacerbations and mortality in a Danish cohort of patients with Chronic Obstructive Pulmonary Disease
Authors: Kristensen A , Sivapalan P , Bagge K , Biering-Sørensen T , Sørensen R , Eklöf J , Jensen JUS 
Published: June 2022

Objectives: Pulmonary Embolism has been frequently reported in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AE-COPD). The study aimed to determine whether COPD patients who receive anticoagulant (AC) therapy have a reduced risk of hospitalization due to AE-COPD and death. Methods: This nationwide population-based study was based on data from the Danish Register of COPD (DrCOPD), which contains complete data on COPD outpatients between 1st January 2010 and 31st December 2018. National registers were used to obtain information regarding comorbidities and vital status. Propensity-score matching and Cox proportional hazards models were used to assess AE-COPD and death after one year. Results: The study cohort consisted of 58,067 patients with COPD. Of these, 5194 patients were on AC therapy. The population was matched 1:1 based on clinical confounders and AC therapy, resulting in two groups of 5180 patients. We found no association between AC therapy and AE-COPD or all-cause mortality in the propensity-score matched population (HR 1.03, 95% CI 0.96-1.10, p = 0.37). These findings were confirmed in a competing risk analysis. In the sensitivity analysis, we performed an adjusted analysis of the complete cohort and found a slightly increased risk of AE-COPD or death in patients treated with AC therapy. This study found a low incidence of pulmonary embolisms and deep venous thrombosis in both groups. Conclusions: AC therapy was not associated with the risk of hospitalization due to AE-COPD or all-cause mortality.
Evaluating occupational performance coaching to support fatigue management for people with multiple sclerosis: A feasibility study
Authors: Askari Sorayya , Kessler Dorothy , Smyth Penelope , Finlayson Marcia 
Published: June 2022

Objective To determine the feasibility of adding coaching sessions to a website (MS INFoRM) that supports self-directed fatigue management for people with multiple sclerosis (PwMS). Design Double-blind, parallel-group feasibility study. Participants and setting Twenty-six PwMS, who experienced severe fatigue (fatigue severity scale > 5.4), were recruited from participants who were ineligible for the main trial testing on the MS INFoRM website. Intervention Six 45-to-60-min sessions of one-on-one coaching plus access to the MS INFoRm website compared to two check-in phone calls plus access to the MS INFoRm website. Both study arms took place over 3 months. Main measures Feasibility parameters included proportion eligible of those screened; proportion consented; missing data; retention and adherence rates. Acceptability was explored through qualitative interviews. Secondary outcomes (self-efficacy and fatigue impact) were measured at baseline and post-intervention. Results 76 people were invited to participate in this add-on study. 40 were interested and screened: 32 were eligible, 26 consented, and were randomized (mean age: 48.5 yrs (SD: 8.7), mean disease duration: 11.5 yrs). Retention was 85% (22 out of 26). Coaching adherence was high (86% attended ⩾ 5 sessions). At 3 months, people in the intervention group showed more improvements in self-efficacy and fatigue impact compared to the comparison group, however, the difference was not statistically significant ( p = 0.471 and p = 0.147, respectively). The intervention was well-received by the participants and there were no adverse events. Conclusion Combining one-on-one coaching sessions along with web-based interventions is feasible and appreciated by the participants, and worth exploring further in a larger trial.
1985 Macromarketing Seminar Abstracts
Authors: Klein Thomas A. 
Published: June 2022

The 1985 Macromarketing Seminar was hosted by George Washington University at Airlie House, Airlie, Virginia, August 15-18. Nearly 50 participants met to discuss research and theoretical developments. Abstracts of formal papers presented at the seminar follow. Readers wishing complete copies of these papers may request them directly from authors. The Eleventh Macromarketing Seminar will be held in Boulder, Colorado, following the American Marketing Association Educators Conference in August 1986. Program Chairman is Professor Donald Shawver, University of Missouri, Columbia. Arrangements Chairman is Professor Charles Goeldner, University of Colorado, Boulder.
Trapped equivalence ratio determination in two-stroke engines
Authors: Bajwa Abdullah U , Patterson Mark , Jacobs Timothy J 
Published: June 2022

The chemical composition of the trapped fuel-air-residual gas mixture controls the nature of combustion in internal combustion engines and thus serves as a key determinant of the ensuing emissions and work production processes. A frequently used trapped composition metric for engine control is the trapped equivalence ratio. Unfortunately, in two-stroke engines, it is unfeasible to accurately determine this using traditional intake flow and exhaust emissions measurements because of the simultaneous occurrence of intake and exhaust processes, which causes: (1) exhaust emissions to be diluted by the slippage (short-circuiting) of fresh air through the exhaust ports, i.e., trapping inefficiencies, and (2) high residual combustion product retainment, i.e., scavenging inefficiencies. The current paper supplements scavenging efficiency data obtained in a previous study for a cross-scavenged, natural-gas, two-stroke engine with experimental trapping efficiency data from the same engine, and characterizes the overall gas-exchange (scavenging + trapping) behavior of the engine at two engine loads, three speeds, and three spark timings. The trapping efficiency experiments use natural gas as a tracer for fresh charge and the total gas-exchange data is used to compute the trapped equivalence ratio. The trapping performance of the engine – which improves with speed and load increase, and spark retardation – along with scavenging, volumetric, thermal, and combustion efficiency changes determine the trapped equivalence ratio of the engine. The relationship between trapped equivalence ratio and NOx emissions is presented and the importance of accounting for scavenging and trapping inefficiencies in accurately determining equivalence ratio is discussed.
Comparison of Maxillofacial Morphology Between Modified Furlow's and Modified two-Flap Palatoplasty in Orofacial Clefts During the Primary Dentition Period
Authors: Yoshida Hiroshi , Takahashi Masahiro , Yamaguchi Tetsutaro , Takizawa Hideomi , Takakaze Momoko , Maki Koutaro 
Published: June 2022

Objective To assess the effect of two palatoplasty procedures, modified Furlow's palatoplasty (F procedure) and modified two-flap palatoplasty (T procedure), on the maxillofacial morphology of unilateral cleft lip and palate (UCLP) and bilateral cleft lip and palate (BCLP) during the primary dentition period. Design Retrospective cohort study Setting Department of Orthodontics, School of Dentistry, Showa University Participants We enrolled 106 pediatric patients (63 boys, 43 girls; aged 4.43  ±  0.34 years) with non-syndromic orofacial clefts who underwent cheiloplasty and palatoplasty. Interventions Patients were divided into four groups according to cleft type (BCLP or UCLP) and palatoplasty procedure type (F or T procedure). Main Outcome Measures Maxillofacial morphology was assessed by examining parameters on lateral cephalograms. Results Multiple comparisons revealed significant differences among N-A, N-ANS, and ANS-PNS distances and SNA and ANB angles among the groups. There were significant differences in N-A, N-ANS, ANS-PNS, SNA, and SNB among the UCLP and BCLP groups. The calculated effect sizes were all within 0.3–0.5. The statistical power was as follows: N-A, 86.41%; N-ANS, 79.77%; ANS-PNS, 97.49%; SNA, 96.88%; and ANB, 99.25%. Conclusions Although UCLP and BCLP both exhibited differences in craniofacial distances and angles, the procedure type (either F or T procedure) had no significant effect on the maxillofacial morphology (as determined by lateral cephalograms). However, to rule out additional bias, patient-specific factors should be considered that may be affected by maxillofacial development when deciding surgical approaches.
Effects of RME on Hearing in UCLP Patients: A Pilot Study
Authors: Fatima Kaleem , Chaudhari Prabhat Kumar , Duggal Ritu , Kharbanda Om P. , Thakar Alok 
Published: June 2022

Objective To assess the changes in hearing after rapid maxillary expansion (RME) and at the end of 6 months retention period in complete unilateral cleft lip and palate (UCLP) patients using pure tone audiometry and tympanometry test. Design Prospective pilot study. Setting Tertiary health care teaching hospital in New Delhi. Patients This study was conducted on 6 UCLP patients in the age range of 6-14 years with normal ear anatomy. All 6 patients had undergone primary repair of cleft lip and palate and required no more than 5 mm expansion in the intermolar region. Intervention RME was done using a Hyrax expander with daily activation of one-quarter turn per day for a period of 15-20 days (0.25 mm per day). Main outcome measure Audiometry and tympanometry readings at the baseline as compared to the post expansion and at the end of 6 months retention period. Results There were no significant changes in the hearing levels on the audiometry test after RME on the cleft side ( p-value −0.51) and the noncleft side ear ( p-value −0.26). No significant changes were observed in the middle ear volume on the tympanometry test after RME on the cleft side ( p-value −0.09) and the noncleft side ear ( p-value −0.28). Conclusion There was no improvement or deterioration in the hearing levels after RME and at the end of 6 months retention period in UCLP patients as evaluated using pure tone audiometry and tympanometry test. Hence RME may be undertaken in UCLP patients safely in terms of hearing is concerned.
A Multisite Study Investigating Child and Parent Proxy Reported Quality of Life in Children With Cleft Lip and/or Palate
Authors: Heppner Celia E. , Crerand Canice E. , Crilly Bellucci Claudia , Sheikh Farah , Woodard Suzanne , Albert Meredith , Conrad Amy L. , Kapp-Simon Kathleen A. 
Published: June 2022

This observational, multisite cohort study explored health-related quality of life (HRQoL) in children with cleft lip and/or palate (CL/P), including interrater agreement and ratings for this group relative to clinical cutoff scores and published means for healthy and chronically ill children. Participants (338 children ages 8-10 years, 45.9% male and their parents, 82.0% female) across 6 sites completed the Pediatric Quality of Life Inventory Generic Core Scales (PedsQL). Intraclass correlation revealed poor interrater agreement for most HRQoL domains. Although ratings were generally higher than those expected for children with a chronic illness, child ratings were below healthy means for school functioning, and parent proxy ratings were below healthy means for all domains except physical functioning. Lower ratings consistent with chronic illness means were found for self-reported emotional and psychosocial functioning in children with cleft lip and palate (CLP), as well as parent proxy-reported emotional, school, and psychosocial functioning for children with cleft palate (CP). Scores were most likely to be in the clinical range for children with CP for social, school, and total functioning. Although parent proxy report provides important information about observed functioning, poor interrater agreement indicates that both child and parent proxy reported HRQoL should be included in outcomes assessment for CL/P. HRQoL ratings may be higher for children with CL/P compared to youth with other chronic illnesses, but psychosocial functioning may be negatively impacted when compared with healthy youth, particularly for emotional, social, and school functioning in children with CLP or CP.
Experimental study on construction vibration during different phases of diaphragm wall-supported deep excavation and its influence on indoor sensitive receivers
Authors: Ko Yung-Yen , Lai Liang-Yu , Lee Gang-Hui , Wang Yu-Fang , Jao Shih-Wei , Fu Tzu-Fun 
Published: June 2022

Construction vibration during deep excavation supported by diaphragm walls was experimentally investigated. First, measurement on the ground vibration induced by panel excavation for diaphragm wall installation was made inside a construction site. Results showed that the vibration level during excavation was much higher than ambient vibration at most frequencies, especially near the fundamental frequencies of the ground and the grab, and the strongest vibration was induced by the grab impacting the ground and guide walls. At another site, indoor ground-borne vibration was measured at two zebrafish laboratories at B1 and 3F of adjacent buildings during phases of existing pavement demolition, panel excavation, and basement excavation. The behavior of zebrafishes was observed simultaneously to examine the influence of vibration. Pavement demolition caused considerable increase in vibration level at B1 for nearly all frequencies, whereas at 3F the increment was more remarkable yet limited to a narrower bandwidth. Excavation of both panel and basement slightly enhanced the vibration magnitude at B1 at frequencies above 63 Hz or higher yet was hardly influential at 3F. Zebrafishes at B1 exhibited more startle response than those at 3F in all phases possibly because the construction vibration at B1 fell within the frequency range of vibration detection of zebrafishes. According to ISO 2631-1, this indoor vibration was perceptible to people only in some situations yet caused no discomfort.
Application and effect evaluation of multidisciplinary team management model: On central venous access device associated skin impairment based on Delphi method
Authors: Li Ji-Yue , Li Jia , Fan Yu-Ying , Lin Xi-Ling , Huang Chun-Li , Qin Hui-Ying 
Published: June 2022

Objective: To establish a multidisciplinary management model based on Delphi method to guide nursing practice and reduce the incidence of CVAD-associated Skin Impairment (CASI) in tumor patients. Methods: On the basis of literature review and focus group interview, the initial item pool of CASI management model for cancer patients was determined. The Delphi method was used to conduct two rounds of letter consultation with 36 authoritative and representative experts to determine the content and weight of indicators of CASI multidisciplinary management model for cancer patients. Results: Most of the research group were experts with bachelor degree or above. More than 90% of experts have worked for more than 10 years; Areas of expertise include oncology care, venous therapy, wound stomatology, and dermatology. The recovery rate of the two rounds of expert correspondence questionnaire was 100%. The authority coefficient of experts was 0.898, indicating a good degree of authority. Kendall’s harmony coefficients were 0.193 and 0.250, with statistically significant differences ( p < 0.001). After two rounds of expert letter consultation, a multidisciplinary management model of CASI for cancer patients was initially formed, which included 15 first-level prevention indexes and 38 second-level prevention indexes of CASI for cancer patients. There were 9 first-level indexes and 16 second-level indexes of CASI treatment in tumor patients. Conclusion: Cancer patients based on Delphi method to construct CASI multidisciplinary management model has high reliability and scientificity, multidisciplinary management model in the management of patients with tumor CASI exploration will provide new methods for central venous catheter nursing and the new way of thinking, will also be intravenous fluids will provide a scientific basis for professional development and quality improvement and practical experience.
Changes in umbilical catheters’ microstructure in vivo: A prospective study
Authors: Sobczak Alina , Kowalik Aleksandra , Homa Marta , Turalska Patrycja , Kwinta Przemko 
Published: June 2022

Background: Umbilical vessels present after birth allow a unique central access for both venous and arterial catheterization, yet the catheterization complications can be misdiagnosed as the complications of prematurity per se. Methods: A prospective observational study of 41 used polyurethane umbilical catheters, both venous and arterial was conducted in a tertiary neonatal intensive care unit. The study consisted of bedside ultrasound imaging and post-removal microbiological and microstructural analysis to assess the in vivo catheters’ changes and their clinical significance. Results: The study has shown that catheters’ surface thrombosis and bacterial colonization happen more often within umbilical venous than within arterial catheters (31% vs 8% in both cases) and are inversely proportional to the patient’s gestational age (thrombosis: Me: 28 weeks vs no thrombosis: 32 weeks; p = 0.05, bacterial colonization: 27 weeks vs no colonization: 30 weeks; p = 0.013), respectively. The clots formed near the catheter’s tip are correlated with catheter’s bacterial colonization. Chemical analysis with energy dispersive spectroscopy showed a higher calcium composition in used catheters (19.89% vs 0%, p = 0.016) and structure analysis in the scanning electron microscopy proved that within hours catheters become covered with an external coating of a constant thickness, not affected by the catheterization time. Conclusion: The following observations give a better insight to the complex in vivo interactions and call for a more intense bedside-monitoring of the indwelling devices.
Lesion size and shape in central vein sign assessment for multiple sclerosis diagnosis: An in vivo and postmortem MRI study
Authors: Al-Louzi Omar , Manukyan Sargis , Donadieu Maxime , Absinta Martina , Letchuman Vijay , Calabresi Brent , Desai Parth , Beck Erin S , Roy Snehashis , Ohayon Joan , Pham Dzung L , Thomas Anish , Jacobson Steven , Cortese Irene , Auluck Pavan K , Nair Govind , Sati Pascal , Reich Daniel S 
Published: June 2022

Background: The “central vein sign” (CVS), a linear hypointensity on T2*-weighted imaging corresponding to a central vein/venule, is associated with multiple sclerosis (MS) lesions. The effect of lesion-size exclusion criteria on MS diagnostic accuracy has not been extensively studied. Objective: Investigate the optimal lesion-size exclusion criteria for CVS use in MS diagnosis. Methods: Cross-sectional study of 163 MS and 51 non-MS, and radiological/histopathological correlation of 5 MS and 1 control autopsy cases. The effects of lesion-size exclusion on MS diagnosis using the CVS, and intralesional vein detection on histopathology were evaluated. Results: CVS+ lesions were larger compared to CVS− lesions, with effect modification by MS diagnosis (mean difference +7.7 mm3, p = 0.004). CVS percentage-based criteria with no lesion-size exclusion showed the highest diagnostic accuracy in differentiating MS cases. However, a simple count of three or more CVS+ lesions greater than 3.5 mm is highly accurate and can be rapidly implemented (sensitivity 93%; specificity 88%). On magnetic resonance imaging (MRI)-histopathological correlation, the CVS had high specificity for identifying intralesional veins (0/7 false positives). Conclusion: Lesion-size measures add important information when using CVS+ lesion counts for MS diagnosis. The CVS is a specific biomarker corresponding to intralesional veins on histopathology.
Case report of fetal liver cirrhosis due to gestational alloimmune liver disease in a primigravida female, in the northeast region of India
Authors: Maheshwari Sandip 
Published: June 2022

Introduction: Fetal liver failure is a major cause of neonatal morbidity and mortality, presenting as acute liver failure and/or congenital cirrhosis. Gestational alloimmune liver disease associated with neonatal haemochromatosis is a rare cause of fetal liver failure. Case report: 24-year-old primigravida on Level II ultrasound scan showed intrauterine live fetus, with the fetal liver showing nodular architecture and coarse echotexture. Moderate fetal ascites were present. Scalp oedema was present with minimal bilateral pleural effusion. Suspicious fetal liver cirrhosis was raised, and the patient was counseled for a poor prognosis of pregnancy. Surgical termination of pregnancy was performed at 19 weeks through Cesarean section, and postmortem histopathological examination revealed haemochromatosis, hence gestational alloimmune liver disease was confirmed. Discussion: The presence of a nodular echotexture of the liver, with ascites, pleural effusion, and scalp oedema suggested chronic liver injury. Gestational alloimmune liver disease-neonatal haemochromatosis is often diagnosed late and patients are therefore referred late to specialized centers, delaying treatment. Conclusion: This case highlights the consequences of late diagnosis and treatment of gestational alloimmune liver disease-neonatal haemochromatosis and emphasizes the importance of a high grade of suspicion of this disease. Level II ultrasound scan should include scanning of the liver, as a part of the protocol. A high grade of suspicion is key for the diagnosis of gestational alloimmune liver disease-neonatal haemochromatosis, and early use of intravenous immunoglobulin should not be postponed to allow longer survival of the native liver.