bluuebunny/crossref_metadata_2025_split huggingface dataset:
Green production of biologically active Ag and Ag-Cu nanoparticles from Prosopis cineraria pod waste extract and their application in epoxidation
Authors: Kumar Prashant , Sharma Praveen Kumar , Chaturvedi Shivani , Singh Suman , Tripathi Shreya , Fatima Huma , Grover Minakshi , Mohapatra Priyabrat , Chanotiya Chandan Singh , Rout Prasant Kumar 
Published: September 2022

Abstract
Bio-nanotechnologically produced nanoparticles (NPs) utilizing waste materials have been the main focus of the current research. There is a need for developing an advanced technology to reduce waste in an eco-friendly way. Therefore, presently the discarded aqueous portion of Prosopis cineraria pods was used after boiling to synthesize Ag and Ag-Cu NPs. FT-IR spectra illustrated the presence of phenyl propenoids and flavonoids were displaying capping and reducing properties. TEM and SEM imaging exhibited an average size of Ag NPs (14 nm) and Ag-Cu NPs (27 nm). The crystallinity nature was confirmed by XRD, and the Cu in Ag-Cu NPs was validated through energy dispersive X-ray analysis. According to the antimicrobial data, Saccharomyces cerevisiae displayed a zone of inhibition (ZOI) of 42.85% (Ag NPs) and 33.98% (Ag-Cu NPs) at lower concentrations (0.0321 mg/ml), while Bacillus subtilis was found most susceptible (85% ZOI) to Ag NPs at 0.5 mg/ml concentration. Further, these NPs (Ag and Ag-Cu) were utilized in the epoxidation of alkene moieties. Ag NPs showed lower conversion (65%) while, Ag-Cu NPs were very active for epoxidation of linalool (93% conversion), suggesting the presence of Cu was facilitated epoxidation. To the best of our knowledge for the first time, the aqueous waste was applied to prepare green NPs for using as antimicrobial agents and synthesis of platform chemical (epoxide) for industrial aspects. These inexpensive ways of producing green NPs is utilized several times and have found potential applications in nano-medicine, therapeutics, modification of monoterpenoids to fine fragrance, etc.
Solvent pre-selection for binary mixtures based on the infinite dilution at activity coefficients in deep eutectic solvent: Tetraethylammonium chloride + Ethylene glycol
Authors: Yang Xueqin , Wang Qiang , Li Jing , Yalikun Nuerbiya , Xu Liang , Ding Zhen 
Published: September 2022

Abstract
The values of activity coefficient at infinite dilution () were reported of 27 solutes in the tetraethylammonium chloride + ethylene glycol deep eutectic solvent at a certain molar ratio 1:2 by inverse gas chromatography (IGC) method at intervals of 10 K from 303.15 to 333.15 K. Then the measured values were used to determine the thermodynamic functions ( and ). The values of selectivity () and capacity () for five extraction problems (e.g. heptane/toluene, benzene/methanol, heptane/thiophene, acetone/ethanol, cyclohexane/benzene, and cyclohexane/ethanol.) were calculated from experimental values as well as compared to literature values of other solvents for the same separation problems. The results indicated that the studied DES is a potential extractant for separation cyclohexane/ethanol and heptane/thiophene problems. The Flory-Huggins interaction parameters () and the gas-to-liquid partition coefficients () were used to evaluate the miscibility between DES and organic probes, and the results showed that alcohols have the best solubility in tested DES. Additionally, the Hildebrand solubility parameters () for tested DES were calculated, and the values of decreased with the increase of temperature.
Minimizing Visible Edges in Polyhedra
Authors: Tóth Csaba D. , Urrutia Jorge , Viglietta Giovanni 
Published: September 2022

Abstract
We prove that, given a polyhedron $\mathcal P$ in $\mathbb{R}^3$, every point in $\mathbb R^3$ that does not see any vertex of $\mathcal P$ must see eight or more edges of $\mathcal P$; this bound is tight. More generally, this remains true if $\mathcal P$ is any finite arrangement of internally disjoint polygons in $\mathbb{R}^3$.
Evaluation of Stresses on Mandible Bone and Prosthetic Parts in Fixed Prosthesis by Utilizing CFR-PEEK, PEKK and PEEK Frameworks
Authors: Shash Yomna H. , Elwakad Mohamed T. , Eldosoky Mohamed A. A. , Dohiem Mohamed M. 
Published: September 2022

Abstract
Introduction: Fixed prosthesis is an appropriate solution for edentulous patients. In fixed prostheses, following “All on four”, titanium frameworks are commonly used to support the implants. However, the limitations of titanium have prompted the researchers to search for alternative materials (e.g. polymers). The success of fixed prosthesis is predicted to be influenced also by bone quality, particularly spongy bone density. Purpose: This study applied finite element investigations to evaluate the stress distribution in the parts of fixed prosthesis and the surrounding bone tissue, using polymeric frameworks in place of titanium, and different densities of spongy bone.Materials &Methods: Fixed prosthesis was constructed on edentulous mandible, then different frameworks (CFR-PEEK 60%, CFR-PEEK30%, PEKK, and PEEK) were stimulated instead of titanium, using different densities of spongy bone, under 300N unilateral force. Results: The choice of framework material depended on the density of spongy bone. Moreover, PEEK framework showed the lowest stress values on bone tissues and the highest stress values on the mucosa. Conclusions: All frameworks could be used in the fixed prosthesis, in the cases of normal and high densities of spongy bone. In low-density case, soft frameworks (PEKK & PEEK) were recommended to reduce the stresses generated on bone tissues.
The Usefulness of Serial Ultrasound in Thyroid Mucosa-Associated Lymphoid Tissue Lymphoma
Authors: Zhang Xiumei , Boxiong Wei , Nong Lin , Zhang Hong , Gao Ying , Ou Jinping 
Published: September 2022

Abstract
Background: Mucosa-associated lymphoid tissue (MALT) lymphoma is an extranodal lymphoma with an indolent natural course. The thyroid gland is an uncommon site of involvement. We aimed to investigate serial ultrasound features during the clinical course of thyroid MALT lymphoma.Methods: We searched our hospital’s pathology database (5418 patients with thyroid malignancy) between January 2000 and July 2022. The medical records and serial ultrasounds of 11 patients with 12 thyroid MALT lymphoma foci were analyzed retrospectively. from Results: An enlarging neck mass, dyspnea, B symptoms, and neck lymphadenopathy were seen at diagnosis in 9 (9/11, 81.8%), 3 (3/11, 27.3%), 2 (2/11, 18.2%), and 9 (9/11, 81.8%) cases respectively. Eleven cases were concomitant Hashimoto thyroiditis. Common ultrasound features included bilateral or unilateral asymmetric goiter or large, solid, and very hypoechoic nodules (11/12, 91.7%) interspersed with linear, reticular hyperechoic, and enhanced posterior echoes (11/12, 91.7%), and neck lymph node involvement (10/11, 90.9%). The Thyroid Imaging and Reporting Data System (TIRADS) categories showed higher diagnostic accuracy (11/12, 91.7%) than real-time ultrasound (2/12, 16.7%) in evaluating thyroid lesions for recommendation of fine-needle aspiration (FNA). Serial ultrasound showed self-limiting changes in three cases, relapse in three cases after subtotal thyroidectomy and chemotherapy, large cell transformation (LCT) in one case after left lobectomy, partial remission in one case, and complete remission after chemo/radiation in four cases; progression to enlarged thyroid nodules occurred in three cases without treatment, with no obvious change observed after diagnosis. Three patients died during follow-up.Conclusion: On sonograms, solid large thyroid nodules or goiter with very hypoechoic and enhanced posterior echoes in the setting of Hashimoto thyroiditis should raise suspicion for MALT lymphoma. TIRADS categories could improve the ultrasound diagnostic efficacy for malignancy. Serial ultrasound examinations demonstrated self-limiting and indolent natures of thyroid MALT lymphoma.
Structure-adapted multi-channel matching pursuit for seismic trace decomposition
Authors: Zhao Zhencong , Rao Ying , Wang Yanghua 
Published: September 2022

Abstract
While the single-channel matching pursuit decomposes a seismic trace into a series of wavelets, the multi-channel matching pursuit examines the lateral coherence of the seismic traces as a constraint to improve the lateral continuity of the decomposition. However, the presence of structures in the subsurface negatively affects the performance of the multi-channel matching pursuit. We proposed a structure-adapted matching pursuit method that uses a dynamic time-warping (DTW) algorithm to estimate the similarity between adjacent seismic traces and extract an optimal wavelet along the dip plane. This structure-adapted implementation would significantly speed up the convergence of the decomposition process. We modified the DTW algorithm by combining the Euclidean distance of the seismic trace and the first-order temporal derivative of the seismic trace. We also updated the amplitudes of all extracted wavelets simultaneously using the least-squares principle. This DTW-based, structure-adapted, multi-channel, least-squares matching pursuit would improve the robustness and accuracy of the seismic trace decomposition.
Bioinformatics study of PCDHB6 as a prognostic marker for gastric cancer
Authors: Huang Lingyu , Liang Wenken , Wei Jianfen , Xu Ziwei , Sha Yu , Deng Yecheng , Ou Minglin 
Published: September 2022

Abstract
Background
Gastric cancer is a common and fatal disease with the highest incidence and mortality in men. Protocadherin beta 6 (PCDHB6) has not been reported much in tumors and the role of PCDHB6 in gastric cancer is not yet clear. Therefore, we aimed to investigate the expression of PCDHB6 in gastric cancer infiltration, invasion and metastasis and to assess the prognostic and functional significance of PCDHB6 in gastric cancer.
Methods
Based on TCGA, GEO database, bioinformatics analysis of PCDHB6 gene was performed from gene expression, survival analysis, gene mutation, immune infiltration, DNA methylation and enrichment analysis. In addition, Real-Time PCR was used to further confirm the role of PCDHB6 in gastric cancer.
Results
PCDHB6 gene was highly expressed in gastric cancer and positively correlated with poor patient prognosis. Real-Time PCR results also showed high expression of PCDHB6 in gastric cancer. PCDHB6 expression was positively correlated with tumor-associated fibroblasts, Basophils, CD4 + memory T-cells, CD8 + T- cells, Eosinophils, Macrophages, Regulatory T-cells and Type 2 T-helper cells were positively correlated with immune infiltration. KEGG and GO enrichment analysis showed that PCDHB6 gene was mainly involved in the regulation of Herpes simplex virus 1 infection, Hippo signaling pathway and cell adhesion pathway.
Conclusions
Our study comprehensive summary and analysis revealed for the first time that PCDHB6 is highly expressed in gastric cancer and is an oncogene. PCDHB6 can be used as a potential prognostic biomarker for gastric cancer and provides a powerful therapeutic target for the treatment of gastric cancer.
Two-Party Quantum Dialogue Protocol with Two-Server in Cross-domain Environment using Double-GHZ-Like Linked Method
Authors: Ma Xiyuan , Gu Mulin , Du Ning , Zhu Hongfeng , Hur Junbeom 
Published: September 2022

Abstract
There is an intuitive connection between GHZ-like states and Cross-domain architecture. Such a connector may lead to a novel way to construct mutual authentication and efficient key agreement protocols between any two clients in arbitrary domain. In this paper, we present a novel rule to link the double-GHZ-Like states which are prepared by the two domain servers respectively. The protocol involves four parties, including two servers and two participants. In this protocol, according to the measured correlation of three-particle entangled state, the communication parties realize mutual authentication by means of the three-particle GHZ-like state prepared by the server. In addition, with the measurement results published by the servers, the two participants perform the double CNOT operations on the corresponding particle sequence according to the negotiation results, and conduct quantum dialogue through the encrypted information held by each other. This is the first time to propose a four-party cross-domain combination of two three-particle GHZ-like states, and to realize the mutual authentication and quantum dialogue of the two-party participants through the corresponding rules. Security analysis shows that the new protocol can resist common external and internal attacks. Compared with the existing two-party or multi-party protocols, this protocol has feasible efficiency.
Prognostic significance of the cachexia index in patients with stages Ⅰ-Ⅲ colorectal cancer
Authors: Kamada Teppei , Haruki Koichiro , Nakashima Keigo , Takahashi Junji , Nakaseko Yuichi , Suzuki Norihiko , Ohdaira Hironori , Eto Ken , Ikegami Toru , Suzuki Yutaka 
Published: September 2022

Abstract
PurposeThe prognostic significance of cachexia index, a novel biomarker of cancer cachexia remains unclear in colorectal cancer (CRC); we evaluated its prognostic significance in CRC.MethodsThis retrospective cohort study included 306 patients with stage Ⅰ–Ⅲ CRC who underwent R0 resection between April 2010 and March 2020. The cachexia index was calculated as (skeletal muscle index [cm2/m2] × serum albumin level [g/dL])/neutrophil-to-lymphocyte ratio. Overall survival (OS) and disease-free survival (DFS) rates were analyzed using a Cox proportional hazards model. ResultsA low cachexia index was obtained in 94 patients. The low-cachexia index group had significantly lower DFS rates than the high-cachexia index group (5-year survival rates, 86.3% vs. 63.1%, p<0.01). In the multivariate analysis, CA19-9 ≥27.9 ng/mL (hazard ratio [HR]: 1.76; 95% confidence interval [CI]: 1.01–3.05, p=0.045), stage III (HR: 4.06: 95% CI: 2.14–7.68, p<0.01), and low cachexia index (HR: 2.22; 95% CI: 1.29–3.80, p=0.004) were significant independent predictors of DFS. The low-cachexia index group had significantly lower OS rates than the high-cachexia index group (87.9% vs. 67.2%, p<0.01). In the multivariate analysis, CA19-9 level ≥27.9 ng/mL (HR: 2.12; 95% CI: 1.19–3.75, p=0.010), stage III (HR: 2.97; 95% CI: 1.56-–5.67, p=0.001), and low cachexia index (HR: 2.40 95% CI: 1.35–4.29, p=0.003) were significant independent predictors of OS. A similar trend was observed in both stage I+II and stage III CRC patients.ConclusionA low cachexia index might be a long-term prognostic factor in CRC patients, including those with early-stage disease.
Predictive Evaluation of Currents For Nano Multi FinFETs Under Geometry Variations
Authors: Khan Shaheen , Khan Irshad , Ajay Ajay Kumar Dadoria 
Published: September 2022

Abstract
Scaling of the transistor is a prime thrust for development of semiconductor industries. In this paper we have evaluated the impact of ION and IOFF current by applying process variation on different device parameters from 20-7nm of FinFET technology and study the behaviour of the digital circuit with scaling of technology. Here the impact on ION and IOFF current is investigated with the variation of Fins in FinFET transistors for High Performance (HP) and Lower Standby Power (LSTP) models along with applying 10% deviation from nominal values in different device parameters. The simulation results shows that by applying 10% deviation from nominal values of the geometric parameters Length (L) Width (WFin), Hight (HFin), Work Function (WFF), Thickness (TFin), and Source and Drain doping, affects ION current in HP N-FinFET of 20nm technology and has lowest Normalize Standard Deviation of 7% and LSTP P-FinFET in 7nm technology has highest 27% of Normalize Standard deviation. Results also shows that with 3% Normalized Standard Deviation in both HP (N,P FinFET) and LSTP (N,P FinFET) in WFF has an enormous impact on IOFF current i.e. Normalize Standard Deviation of 117% compared to variation in other device parameters which causes maximum Normalize Standard Deviation of 51% and minimum of 5%. Here variations in parameters are done taking 2,4,8,16 fins in FinFET. These experiments are carried on HSPICE simulator at 27°C temperature by using 20-7nm Berkley Predictive Technology Module.
The temporal variation of blood lead levels in Chinese urban children: the China Nutrition and Health Survey (CNHS) 2002 to 2012
Authors: Liu Xiaobing , Gong Zhaolong , Zhang Yu , Zhang Huidi , Wang Jun , Tan Hongxing , Piao Jianhua , Yang Lichen , Yang Xiaoguang 
Published: September 2022

AbstractLead (Pb) pollution is a global public health problem and adversely affects children health across a wide range of exposure levels. This study was conducted to evaluate the blood Pb levels (BLLs) of Chinese urban children aged 6−11 years and to describe the temporal variations from the China Nutrition and Health Survey (CNHS) in 2002 and 2012. A total of 2182 (1036vs.1146) Chinese urban children were selected in the CNHS 2002 and the CNHS 2012 using the multistage stratified cluster random and probability proportional to size sampling method. The BLLs of urban children were determined using inductively coupled plasma mass spectrometer (ICP-MS), whilst the prevalence of BLLs >50 µg/L and >100 µg/L were calculated, as well as the reference values (RV95s: the upper limit of 95% confidence interval of 95th percentile). From the CNHS 2002 to the CNHS 2021, the median BLLs of Chinese urban children had obviously changed from 67.4 µg/L to 36.9 µg/L, and the RV95s of BLLs had also descrended from 149.1 µg/L to 107.9 µg/L. In addition, the prevalence of BLLs with >50 µg/L and >100 µg/L had markedly decreased from 74.0% and 18.2% in the CNHS 2002 to 28.4% and 5.2% in the CNHS 2021. In conclusion, the BLLs of Chinese urban children had been definitely improved in the past 10 years. However, the findings of our study suggested that it is imperative to implement the monitoring and evaluating and to continue control Pb exposure.
Evaluating the synergy between water-energy-food nexus and decoupling pollution- agricultural growth for sustainable production in the agricultural sector
Authors: Naghavi Somayeh , Mirzaei Abbas , Sardoei Mohsen Adeli , Azarm Hassan 
Published: September 2022

Abstract
Today, growing the production of the agricultural sector in order to meet the increasing demand of food is happening through excessive consumption of water resources, energy, chemical fertilizers and pesticides, especially in developing countries. Therefore, the present study aims to design a new approach for sustainable management of resources and realization of clean production in the agricultural sector. In order to design the new approach of the present study, the integration of two concepts of water-energy-food (WEF) nexus and decoupling pollution- agricultural growth (DEC) was used. The proposed approach is modeled through the multi-objective programming model by optimizing the WEF and DEC indices, which is the first research effort in this field. In this regard, the performance of this approach was evaluated in Jiroft county in Kerman province, Iran. The results of the study showed that the consumption of chemical fertilizers and pesticides in the optimal pattern with the simultaneous provision of WEF and gross margin (GM) goals (Optimal 1) is about 110 kg and 0.19 liters per hectare, respectively, more than the proposed pattern (Optimal 3). On the other hand, the consumption of water and energy resources in the optimal pattern with the simultaneous provision of DEC and GM goals (Optimal 2) is about 8785 cubic meters and 1108 MJ per hectare more than the proposed pattern (Optimal 3), respectively. Therefore, this approach, due to the simultaneous integration of two concepts of sustainable development in the agricultural sector, can overcome the weakness of the WEF nexus in not paying attention to the issues of environmental pollution affected by the use of chemical inputs and the weakness of separating pollution- agricultural growth in not paying attention to the management of water and energy resources in the agricultural sector.
CFD modeling of the turbulent airflow over open hilly terrain: Effect of inhomogeneous ABL in neutral conditions
Authors: AMAHJOUR Narjisse , Sofi Anas , Galvánc José Rafel Rodríguez , Khamlichi Abdellatif , kharrim Abderahman El 
Published: September 2022

Abstract
The implementation of the wind turbine is the major issues in the wind engineering sector. However, the presence of the wind turbines in the lower part of the atmospheric boundary layer (ABL) requires adequate study for the simulation of turbulent airflow the wind farm situated on hilly terrain. In this work, the inflow profiles with the wall treatment are examined and investigated to ascertain an equilibrium profile through the whole of the flat terrain. The purpose of this work is to present a general scalable wall-function roughness modification under a modify limitation for the CFD modeling of ABL flows by using the standard k-ε turbulence model in case of a neutral condition. In the otherwise, the application of the homogeneous conditions of the boundary layer in the presence of the complex topographic and the sensitivity studies of the inflow conditions for predicting the air velocity over hilly terrain are carried out. The methodology is implemented in the Finite Element (FE) commercial code COMSOL 5.4 by means of the User-Defined Equation (UDE). The numerical results are compared with CRIACIV boundary layer wind tunnel experimental data. We indicated that the approach used can be led to achieve a homogeneity of neutral ABL, which yields to give an accurate estimation for velocity and turbulence distribution on the presence of the hill. The obtained results are in good correlation with published experimental data in the case of the inhomogeneous surface, and it is observed that use of the scalable wall-function with roughness to solve the near wall region improves the forecast of flow.
SARS-CoV-2 is losing the CGG-CGG genetic footprint. Working sample of August 2022
Authors: Romeu Antonio R. 
Published: September 2022

Abstract
This work should be seen as a timely delivery of results of a longitudinal study on the arginine codon usage bias in the arginine pair of the SARS-Cov-2 S protein polybasic furin cleavage site. The work sample was made up of virus sequences from NCBI Virus and GISAID databases, with August 2022 as release date. Bats harbour a number of emerging viruses, many of which are highly pathogenic in humans, including the closest relative of the SARS-CoV-2. Everything suggests that progenitor of SARS-CoV-2 jumped into humans, and during undetected human-to-human transmission, a SARS-CoV-2 progenitor acquired from human mRNA transcripts, a fragment of 12-nucleotides that properly inserted in the S gene gave rise to the SARS-CoV-2 polybasic furin cleavage site. This exogenous 12-nt-long sequence has the CGG-CGG genetic footprint that integrated into the S gene coding reading frame, lets encoded the furin site arginine dimer. In this region of S gene and/or S protein, an evolutionary pressure would operates in opposite directions. At the phenotype level, this arginine dimer must remain fixed or consolidated. However, at the genotype level, the virus optimizes the CGG-CGG arginine pair code to achieve more favourable arginine codons. Based on NCBI Virus and GISAID databases as a source of information, and using Perl scripts, here I show that 165 out of 126,727 (0.1302 %) NCBI Virus S protein sequences show synonymous base substitution in the furin site arginine dimer. I have also found this loss of the CGG-CGG code in 21 out of 18,750 (0.1120 %) GISAID S protein sequences. Results provide insight into the evolutionary effect on this strategic regions of the SARS-CoV-2 S protein.