bluuebunny/crossref_metadata_2025_split huggingface dataset:
Non-compaction and dilated cardiomyopathy: genotypic, phenotypic and prognostic differences
Authors: Vaykhanskaya T. G. , Sivitskaya L. N. , Levdansky O. D. , Kurushko T. V. , Danilenko N. G. 
Published: November 2022

Aim. To study and compare genotypic and phenotypic signs in patients with non-compaction cardiomyopathy (NCM) and dilated cardiomyopathy (DCM), to conduct a comparative analysis of clinical outcomes and 5-year cumulative survival of patients with NCM and DCM.Material and methods. The study included 144 unrelated patients with cardiomyopathy: NCM (n=74) and DCM (n=70). Mean age was 39 [30; 49] years (men, 96 (66,7%); left ventricular ejection fraction (LVEF) was 30,5 [24; 46]%. A comprehensive clinical examination included electrocardiography, Holter monitoring, echocardiography, cardiac magnetic resonance imaging, coronary angiography, DNA diagnostics (NGS+Sanger), cascade screening, and cosegregation analysis. To assess clinical outcomes, the NCM group was divided into 2 subtypes according to baseline LV systolic function (NCM/DCM phenotype — 50 individuals with LVEF ≤49%; and isolated NCM — 24 patients with LVEF ≥50%). The following adverse events were assessed as the composite endpoint: cardiovascular death, heart transplantation (HT), sustained ventricular tachycardia, ventricular fibrillation, successful cardiopulmonary resuscitation, cerebral thromboembolism. The follow-up period was 62 months.Results. Among patients with LVEF ≤49% at a 5-year follow-up, 37 (74,0%) of 50 patients with the NCM/DCM phenotype and 41 (58,6%) of 70 patients with DCM achieved composite endpoint. Out of 24 patients with NCM with LVEF ≥50% (median LVEF, 56 [51; 61]%), 2 (8,3%) patients achieved composite endpoint (χ2=28,8; p=0,001). In the NCM/DCM group with LVEF ≤49%, a higher level of pathogenic genetic variants (64% vs 41,4%/DCM vs 29,2%/NCM; χ2=11,4; p=0,003), cerebral thromboembolism (χ2=11,8; p=0,003) and HT (χ2=10,6; p=0,005). The results of the 5-year survival analysis (Kaplan-Meier) showed a worse prognosis for NCM with LVEF ≤49% compared with DCM (log rang: χ2=11,5; p=0,001) and isolated NCM (log rang: χ2=17,02; p=0,0001). In the overall cohort (n=144), gene-positivity was also associated with worse prognosis (log rang: χ2=5,38; p=0,02).Conclusion. In the present study, patients with dilated subtype of NCM showed a worse prognosis compared with DCM and isolated NCM. Heart failure progression and cerebral thromboembolism were the most common complications in patients with NCM/DCM.
Enhancement of the bond behaviour between sand coated GFRP bar and normal concrete using innovative composite anchor heads
Authors: Shakiba Milad , Hosseini Seyed Mohammad , Bazli Milad , Mortazavi Seyed Mohammad Reza , Ghobeishavi Mohammad Ali 
Published: November 2022

AbstractAnchor heads could efficiently address the bond weakness between Fibre-Reinforced Polymer bars and concrete. This experimental study enhanced the bond behaviour between GFRP bars and concrete using three innovative anchorage systems made from glass fibre cloth and epoxy resin. A direct pullout test was used to study the bond-slip performance between the bar and the concrete. Test variables were GFRP bar diameter (3 diameters), concrete compressive strength (20.4 and 40.2 MPa), and anchor system (three different types). Based on the test results, in low-strength concrete (i.e. 20.4 MPa) samples, the anchor system efficiency was not promising, and the failure occurred between the concrete and anchors. However, for higher strength concrete (i.e. 40.2 MPa) samples, the ultimate developed tensile load increased between 14 and 68% for different bar sizes and anchorage systems compared to the unanchored control specimens.
Unfavorable maternal outcomes: age structure and territorial distribution
Authors: Berseneva S. N. , Isaeva N. V. , Padrul M. M. , Chercasova E. V. 
Published: November 2022

Objective. To analyze and evaluate the factors connected with age and territorial distribution among women with unfavorable maternal outcomes.
Materials and methods. A retrospective epidemiological analysis of official statistics data on all cases of unfavorable maternal outcomes (deceased women and women with near-miss "almost dead") by age and structure at the place of residence (city, village) in comparison with successful outcomes in Perm Krai (PK), Privolzhsky Federal Region (PFR) and the Russian Federation (RF) for 19972020 was carried out.
Results. In the age structure of deceased women in PK, the main share of 46.7 % was occupied by women aged 2029 and 3039 years, that differed from the comparison group. Among the mothers with successful outcomes in PK, PFR and RF, women aged 2029 years were in the first place 59.3, 62.5 and 60.2 %, respectively, that is 1.3 times higher than the corresponding proportion in MM. In the second place, there were women aged 3039 years 29.6; 27.9 and 29.1 %, respectively, that is 1.6 times less than the deceased women of the corresponding age. The percentage of young mothers aged 1519 was 9.2; 7.7 and 8.9 %, respectively, that is 1.4 times higher than that of the deceased women.
The age structure of women with failed maternal mortality (FMM) differed slightly from that of deceased women and significantly from all puerperas in PK, PFR, RF. Thus, according to the ave-rage longterm data, the main share of women with FMM was women aged 2029 years 51.8 %. The percentage of puerperas aged 2029 years in PK, Privolzhsky Federal Region and the Russian Federation was 59.3, 62.5 and 60.2 respectively. In the second place in PK are women with FMM aged 3039 years 31.5 %. The share of puerperas aged 3039 years in PK, PFR and RF is 29.6 %, 27.9 % and 29.1 %, respectively. In the third place, there are young puerperas with FMM aged 1519 years 14.8 %. The proportion of such patients in PK, PFR and RF is 9.2, 7.7 and 6.6 %, respectively.
According to the average longterm data, the proportion of urban residents prevailed among the deceased women 60.0 %. In the rural areas, the proportion of women who died was 40.0 %.
By the place of residence, the share of women with FMM did not differ from the corresponding data in the MM group and amounted to 57.4 % in the city and 42.6 % in the village. In PK, PFR and RF, this ratio was 72.7 and 27.3 %; 71.6 and 28.4 %; 73.3 and 26.7 % respectively in all the compared territories).
Conclusions. The risk groups for MM and FMM were women aged 2029 years, residents of the city and village, high-risk group rural women 3039 years.
Financing Research in lnstitutions of Higher Education: Ways to ln­crease the lncome of Universities
Authors: Ваулин Д.В. 
Published: November 2022

Рассмотрены различные аспекты выполнения учреждениями высшего образования государственных заданий. Представлены предложения по внедрению передовых экономико-организационных методов повышения доходов вузов на основе опыта учреждений высшего образования США и Великобритании в проведении исследований по лечению редких и генетических заболеваний. Материалы статьи ориентированы на государственных служащих, руководителей высших учебных заведений, контрольноревизионного управления Министерства финансов Российской Федерации.
Various aspects of the implementation of state tasks by institutions of higher education are considered. The paper presents proposals for the introduction of advanced economic and organizational methods to increase the income of universities based on the experience of higher education institutions in the United States and Great Britain in conducting research on the treatment of rare and genetic diseases. The materials of the article are aimed at civil servants, heads of higher educational institutions, the control and audit department of the Ministry of Finance of the Russian Federation.
ProЫems of Transition to а Distance Format of Teaching Disciplines of the Professional Cycle in а Technical University
Authors: Кузьмина Н.А. , Широкова В.В. 
Published: November 2022

Рассмотрены трудности преподавания технических дисциплинам при незапланированном переходе на дистанционный формат обучения. Представлены направления и результаты исследования, посвященного выявлению причин низкой успеваемости обучающихся на примере анализа освоения содержания дисциплины «Управление эксплуатационной работой». Предложены направления методической и работы преподавателей, ориентированной на оптимизацию учебного процесса в условиях дистанционного обучения.
The diffi culties of teaching technical disciplines during an unplanned transition to a distance learning format are considered. The directions and results of a study devoted to identifying the reasons for the low academic performance of students are presented on the example of the analysis of mastering the content of the discipline «Management of operational work». The directions of methodical and work of teachers, focused on the optimization of the educational process in the context of distance learning, are proposed.
The possibility of applying stochastic Petri nets to space systems for survivability analysis
Authors: Брусков А.А. 
Published: November 2022

Исследуется возможность использования стохастических сетей Петри при анализе отказов и живучести в нескольких состояниях на примере космических систем. Анализ отказов с несколькими состояниями дает больше информации, чем традиционный бинарный анализ надежности о поведении системы при ухудшении состояния ее работы и продвижении к полному отказу. Анализ живучести фокусируется, среди прочего, на распространении сбоев в системе или сети, и после отказа узла или компонента оценивается, например, будет ли система испытывать постепенную деградацию или катастрофический отказ.
In this paper, I explore the possibility of using stochastic Petri nets in the analysis of failures and survivability in several states, using space systems as examples. Failure analysis with multiple states provides more information than traditional binary reliability analysis about the behavior of the system during deterioration and its progress to complete failure. Survivability analysis focuses, among other things, on the propagation of failures in the system or network, after the failure of a node or component, and it evaluates, for example, whether the system will experience gradual degradation or catastrophic failure.
Numerical modeling of the dynamics of ionospheric-plasmospheric exchange in calm and disturbed conditions
Authors: Ишанов С.А. , Кащенко Н.М. , Зубков Е.В. , Зинин Л.В. , Дёмин С.А. 
Published: November 2022

На основе нестационарной гидродинамической модели ионосферы и плазмосферы, основанной на представлении о глобальной динамике ионосферной плазмы в результате комплексного действия процессов химической кинетики, амбиполярной диффузии плазмы вдоль геомагнитных силовых линий, теплопереноса с учетом обмена энергией между нейтральными и заряженными компонентами, взаимодействия плазмы с нейтральным ветром, исследованы вариации макроскопических параметров – скоростей, температур и концентраций – тепловой плазмы в различных гелиогеофизических условиях. Характерными свойствами околоземной космической плазмы являются: многокомпонентность, анизотропность, нелинейность, сильное изменение физических характеристик по пространственным переменным, большие временные и пространственные масштабы рассматриваемых явлений. Для решения модельных уравнений непрерывности, движения и теплового баланса предложены вычислительные методы.
Based on a non-stationary hydrodynamic model of the ionosphere and plasmasphere, founded on the concept of the global dynamics of the ionospheric plasma as a result of the complex action of chemical kinetic processes, ambipolar plasma diffusion of directed geomagnetic force waves, heat transfer, taking into account the dependence between neutral and charged components, and the interaction of plasma with a neutral wind, variations macroscopic parameters (velocity, temperature and concentrations) of plasma interaction in various heliogeophysical conditions. Characteristics of the near-Earth space plasma are multicomponent, anisotropic, non-linear, a strong change in physical characteristics in terms of volume variables, large time and scale scales of the proposed objects. Computational methods are proposed for solving model constraints, motion and heat balance.
Model of optimal reliability management of electronic document management system executive authority
Authors: Царькова Е.Г. 
Published: November 2022

Рассматривается математическая модель работы системы управления электронным документооборотом специального назначения с использованием теории массового обслуживания. Представлена постановка задачи организации работы системы документооборота в форме многофазной системы массового обслуживания, для которой вычислены стационарные вероятности системы. Предлагается модель функционирования системы с динамической дисциплиной обслуживания заявок, формализуемой в форме задачи оптимального управления с возможностью управления процессом оптимизации с помощью изменения дисциплиной обслуживания заявок, что позволяет получать существенный прирост эффективности системы документооборота при заданных ограничениях на используемые ресурсы.
The paper considers a mathematical model of the operation of a special-purpose electronic document management system using queuing theory. A statement of the task of organizing the work of the document management system in the form of a multiphase queuing system, for which the stationary probabilities of the system are calculated, is presented. A model of the functioning of a system with a dynamic discipline of application service, formalized in the form of an optimal control problem, is considered. The possibility of managing the optimization process by changing the discipline of application service is noted, which allows for a significant increase in the efficiency of the document management system under given restrictions on the resources used.
Automatic generation of test tasks to control knowledge of software reliability assessment methods
Authors: Павлов Е.М. , Рыжов А.В. , Петров С.А. 
Published: November 2022

Целью данной статьи является описание процесса автоматизации составления тестовых заданий для контроля знаний по методам оценки надежности программного обеспечения. Рассмотрены виды математических моделей, используемые в разработанной системе генерации тестовых заданий, и их свойства. Описаны особенности пользовательского интерфейса. Также дано описание процесса генерации заданий, включающего в себя подготовку исходных данных с расчетом показателей по соответствующим моделям и формирование текстовых файлов с изображениями.
The purpose of this article is to describe the process of automation of test-question generation procedure to control knowledge of software reliability assessment methods. The article describes types of mathematical models used by the developed test generation system and their properties. Features of the user interface are described. It also describes the process of generation of test tasks, which includes the preparation of initial data with the calculation of indicators by appropriate models and the formation of text files with images.
Betamethasone Toxicity Induced by Topical Maternal Exposure Prior to Fertilization in Heart of Newborn Rabbits
Authors: Nwaiser Fatemah Al , Bekht Gamal , Sedky Azza 
Published: November 2022

Background: Betamethasone treatment is widely used and recommended worldwide. Although, there are no enough studies to look for the risk or potential alterations due to accumulation of this drug before fertilization. In addition, previous studies payed attention to intramuscular injection during pregnancy neglecting the long-term impact of the use of topical solutions. So, the aim of the present study was to determine this side effect. Methods: We used two doses of betamethasone: 0.02 and 0.2 mg/Kg b.w. were and at the end of the experimental period (after 3 weeks of delivery), six new-born rabbits of both sexes (1 new born rabbit per mother) were dissected under light anesthesia and heart samples were collected. All the measurements were performed in one assay. Result: The results of this study revealed maternal exposure to betamethasone prior to fertilization, induced oxidative stress, alterations in levels of enzymes. Furthermore, these biochemical alterations were supported by histopathological and ultrastructural observations. So, this study suggested that females; desiring to be pregnant, should stop treatment of psoriasis with betamethasone before fertilization to avoid heart toxicity of their offspring.
HASIL GUNA PENILAIAN PADA PEMBELAJARA PJOK DI SMPN 1 BANJARBARU
Authors: Maulida Siti , Rahmadi Rahmadi , Hamid Abdul 
Published: November 2022

Pada penelitian ini peneliti memiliki tujuan untuk mengetahui hasil guna penilaian pada pembelajaran PJOK hanya sampai dengan rapot atau di arah kan ke prestasi pada peserta didik di SMPN 1 Banjarbaru. Penelitian ini menggunakan penelitian kuanlitatif dengan metode ex post facto Sampel dari penelitian adalah guru PJOK di SMP Negeri 1 Banjarbaru sebanyak 4 orang. Pada penelitian ini peneliti menggunakan analisis data yaitu statistic deskriptif yang disajikan dalam presentasi. Teknik Sampel yang digunakan Sampling Purposive dengan pertimbangan SMPN 1 merupakan sekolah favorit di Banjarbaru. Pada penelitian ini maka didapatkan hasil guna atau manfaat penilaian hasil belajar pada mata pelajaran PJOK di SMPN 1 Kota Banjarbaru bahwa tidak terlaksananya atau tidak ada tindak lanjut ke arah prestasi bagi siswa yang mendapatkan penilaian bagus dalam pembelajaran PJOK.
Crack Coalescence Behavior of Rock-Like Specimens Containing Two Circular Embedded Flaws
Authors: Bi Jing , Tang Jincai , Wang Chaolin , Quan Daguo , Teng Mingyang 
Published: November 2022

Abstract
Experimental research on the growth of internal flaws has rarely been reported due to the fact that it is difficult to cut internal flaws in specimens and cannot capture the initiation and propagation processes of internal flaws through direct observations. This paper proposed a method for creating internal flaws in specimens by utilizing the volatilization of camphor. A series of compression tests were performed on rock-like specimens including two embedded circular flaws, and CT techniques were used to investigate the internal damage behavior of flawed specimens. Experimental results illustrate that the strength and deformation properties of flawed specimens increase nonlinearly with the confining pressure as well as flaw inclination angle. Crack coalescence patterns and failure modes of flawed specimens depend on not only the confining pressure but also the flaw inclination angle. The crack coalescence pattern varies from wing crack coalescence to mixed tension-shear crack coalescence and then to the shear crack coalescence as the crack inclination angle increases. Confining pressure contributes to shear crack growth and has an inhibiting effect on the propagation of tension cracks. For specimens with the same flaw inclination angle, the failure mode changed from tension failure to mixed shear-tension failure or from mixed shear-tension failure to pure shear failure with the increase of confining pressure.
Rough River Dam Safety Modification Project Evolution
Authors: Shifflett Steven , Ailstock Will 
Published: November 2022

Abstract
This paper is a case study documenting how the Rough River Dam Safety Modification Project evolved over time. Rough River Dam is an embankment dam located in west-central Kentucky that is owned and operated by the U.S. Army Corps of Engineers (USACE) for flood risk management. The project has a right abutment cut-and-cover outlet conduit founded upon karstic limestone. In 2012, a Dam Safety Modification Report (DSMR) was completed that identified multiple internal erosion-related potential failure modes requiring mitigation. The DSMR recommended a multi-phased approach. The Phase I project included construction of a work platform in order to perform exploratory drilling and grouting for two partial grout lines. The Phase II project was to consist of grout line completion, construction of a full-length cutoff wall over and around the existing outlet conduit, grouting within the outlet conduit, and construction of a downstream filter. Based on encountered conditions, the Phase I grouting contract was modified to complete both partial grout lines for slurry control prior to cutoff wall construction. During design of the Phase II cutoff wall, the existing outlet conduit was determined to be structurally inadequate to support the cutoff wall. A Supplemental DSMR recommended a new left abutment outlet works to permit the existing conduit to be severed and to allow for construction of the full cutoff wall across the dam foundation. The Phase II design was completed in the fall of 2021. This paper summarizes the key information, findings, and decisions that informed the final direction of the project.
Analysis of Perforation Erosion Through Computational Fluid Dynamic Modeling
Authors: Zhang Yiming , Wang John Yilin 
Published: November 2022

Summary
Field and experimental data have shown that perforation erosion during shale gas stimulation invalidates the assumption of a constant coefficient of discharge. However, perforation erosion is not fully understood yet. In this work, a perforation erosion model was built using computational fluid dynamics (CFD) and validated against laboratory data. We then conducted parametric studies to investigate the impact of treatment rate, proppant concentration, proppant size, and fluid viscosity on perforation erosion. Our results demonstrated that a higher treatment rate and larger proppant lead to higher erosion to the perforation diameter. Perforation erosion decreased when fluid viscosities increased from 10 to 100 cp, and then increased when the fluid viscosity was increased to 1,000 cp. Our new understandings could be applied to improve perforation design in shale wells.
A new firefly algorithm with an improved attractiveness module
Authors: Liu Jianxun , Shi Jinfei , Hao Fei , Dai Min , Zhang Zhisheng 
Published: November 2022

Abstract
Firefly algorithm(FA) is a very classic meta-heuristic algorithm, which is widely used in various fields to solve complex continuous optimization problems. However, in the actual engineering optimization process, the global optimization efficiency and convergence behavior of the FA need to be further improved. Therefore, we conducted modular research on the firefly algorithm and found that the attraction module of the FA has the problem of losing its attraction to distant fireflies. In order to improve the problem, an improved attractiveness module is proposed by the paper. The improved attractiveness module still has obvious attractiveness for long-distance fireflies. In order to enhance the exploration efficiency of the FA, the new firefly algorithm with an improved attractiveness module(IAM-FA) introduces a logarithmic spiral path. The IAM-FA contains 4 undetermined parameters. The four optimal parameters are determined through simulation.In the experiments on 20 benchmark functions and 4 real design cases, the IAM-FA shows excellent performance compared with other variant algorithms.