bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deep Mining Algorithm of Online Purchase Behavior Data Based on Decision Tree Model
Authors: Cui Jiayi 
Published: September 2022

Abstract
It is difficult to mine online buying behavior data by ignoring the classification of online buying behavior data, and the precision and recall are both on the low side. The training set of online buying behavior data is processed by top-down recursion, and a single decision tree is created recursively, and a decision tree classification model is constructed. Based on the classification results of behavior data, the regular estimation of online shopping features is calculated by preprocessing customer behavior features, and the deep mining algorithm is designed. Experimental results show that the decision tree model has good data clustering effect. Based on this, the precision and recall of online shopping behavior data mining are high, and the application performance is ideal.
Çerçeve sözleşme kavramı, çerçeve sözleşmelerin amacı ve ekonomik fonksiyonu
Authors: ŞEN DOĞRAMACI Hayriye 
Published: September 2022

Sosyal ve ekonomik ihtiyaçlar zamanla değişiklik gösterir. Kişiler arasındaki hukuki ilişkilerin de bu değişikliğe paralel olarak esnek bir biçimde düzenlene-bilmesi oldukça önemlidir. Türk Hukuk sistemine hâkim olan sözleşme özgür-lüğü ilkesi ve onun bir alt görünümü oluşturan tip ve içerik özgürlüğü, sözleş-meler hukuku alanında arzu edilen esnekliği sağlamaya hizmet eder. Çerçeve sözleşmeler hukuki dayanağını sözleşme özgürlüğü ilkesinden alır. Çerçeve sözleşmeler, borçlar hukuku alanında yer alan ve edim değişimini konu alan sözleşmelerden değildir. Çerçeve sözleşmeler, edim değişimini konu alan ileride yapılacak münferit sözleşmeleri tamamlayıcı bir rol üstlenir.
Edim değişimini konu almayan ve birden çok münferit sözleşmeyi tamamla-makla görevli çerçeve sözleşmeler her şeyden önce taraflar arasında sürekli bir ilişkiye vücut verdiği için, tüm sürekli borç ilişkileri için söylenebilecek birtakım avantajlara sahiptir. Çerçeve sözleşmelerin bunun ötesinde sürekli bir borç iliş-kisinde karşılaşılabilecek risk ve belirsizlik faktörlerine karşı nasıl görev üstlen-diği onun ekonomik fonksiyonunun belirlenmesiyle ortaya çıkarılacaktır. Bu çalışmada hukukun ekonomik analizine yönelik kaynaklardan yararlanılarak, çerçeve sözleşmelerin ekonomik fonksiyonu ortaya konulmaya çalışılacaktır.
Role of dihydropyridine calcium channel blockers in coronary bypass surgery using the radial artery graft
Authors: Zatolokin V. V. , Vechersky Yu. Yu. , Manvelyan D. V. , Kozlov B. N. 
Published: September 2022

Aim. To assess the effect of a pharmacological protocol for the prevention of radial artery spasm, which is based on the systemic and local use of dihydropyridine calcium channel blockers, on the long-term outcomes of autoarterial coronary artery bypass grafting.Material and methods. According to the protocol, oral nifedipine at a dose of 5 mg/day is prescribed 3 days before surgery. Then, after the radial artery is isolated, the vessel is preserved in a solution of nifedipine (adalat) until it is used. After releasing the clamp from the aorta, a nifedipine (adalat) is infused intravenously at a dose of 0,63 mg/h. In the postoperative period, the infusion of nifedipine continues for 6 hours. In the future, patients are recommended to take dihydropyridine calcium channel blockers at a dose of 5 mg/day after discharge from the hospital.Results. The use of the pharmacological protocol (n=225) is associated with a lower number of major cardiovascular events (mortality, myocardial infarction, stroke) compared with the control group (n=230) (9,3% and 15,7%, p=0,031) during the 5-year follow-up. This result was achieved mainly by reducing the incidence of myocardial infarction (6,2% and 12,6%, p=0,018). Also, the use of the pharmacological protocol led to a decrease in repeated revascularizations (4,4% and 16,1%, p=0,0001) compared with the control group.Conclusion. The use of a pharmacological protocol for the prevention of radial artery spasm based on the systemic use of dihydropyridine calcium channel blockers improves the long-term outcomes of autoarterial coronary artery bypass grafting.
Influence of implantation of a novel domestic prosthetic aortic valve on the functional class of heart failure one year after surgery
Authors: Petlin K. A. , Kosovskikh E. А. , Chernykh Yu. N. , Kozlov B. N. 
Published: September 2022

Aim. To assess the severity of heart failure (HF) 1 year after aortic valve replacement with a novel bioprosthetic valve with the “easy change” system.Material and methods. The study included 59 patients (24 men and 35 women) diagnosed with degenerative aortic valve disease without concomitant cardiac pathology. The mean age of the patients was 69,6±4,3 years. An assessment of NYHA HF class using six-minute walk test was carried out. The venous plasma level of N-terminal pro-brain natriuretric peptide (NT-proBNP) before and after surgery was also used to determine the severity of HF. In 31 patients (52,5%), NYHA class III HF was determined before surgery.Results. Comparative analysis of HF classes revealed a significant difference. Thus, after implantation of MedEng-BIO prosthetic aortic valve, the distance of the six-minute walk test increased by an average of 125 m (p=0,001). NT-proBNP level decreased from 162,2 pg/ml to 63,7 pg/ml (p=0,003).Conclusion. One-year follow-up of patients after implantation of a novel bioprosthetic aortic valve showed an objective decrease in the severity of HF according to six-minute walk test and NT-proBNP level in venous blood plasma.
Inhospital changes of left ventricular diastolic function in patients undergoing coronary bypass surgery
Authors: Mingalimova A. R. , Drapkina O. M. , Bikbova N. M. , Sagirov M. A. , Mazanov M. Kh. , Timerbaev A. V. , Argir I. A. 
Published: September 2022

Aim. To evaluate changes of left ventricular (LV) diastolic function in patients with multivessel coronary artery disease before coronary artery bypass grafting (CABG) and in the early postoperative period (7-10 days), as well as to assess the relation- ship between diastolic LV dysfunction and postoperative atrial fibrillation (POAF).Material and methods. This original prospective study of included 50 patients undergoing CABG at the Cardiac Surgery Unit № 1 of the N. V. Sklifosovsky Research Institute for Emergency Medicine from December 2020 to December 2021. All patients underwent standard echocardiography before and after surgery. Diastolic function was assessed using the following parameters: septal mitral annulus velocity (e’septal), lateral mitral annulus velocity (e’lateral), the ratio of the peak early transmitral velocity to peak early diastolic velocity of the mitral annulus movement (E/e’), left atrial volume index (ml/m2), peak tricuspid regurgitation velocity (m/s), the ratio of the peak early to late filling velocity (E/A).Results. After CABG, 35 patients maintained sinus rhythm in the early postoperative period (group 1), while 15 patients had POAF (group 2). According to echocardiography, type 1 diastolic dysfunction prevailed in both groups; types 2 and 3 LV diastolic dysfunction were not identified. Among the parameters characterizing myocardial relaxation, in group 1 after CABG, a significant increase in the peak E (p=0,001) was noted, and due to this, the normalization of the E/A ratio was recorded (p<0,0001). An increase in e’lateral (p=0,05) was also revealed, in connection with which an increase in the E/e’ (p=0,02) was noted. In the group of patients with POAF, such changes were not detected. Left atrial volume index (ml/ m2) was significantly higher in the POAF group (p=0,02).Conclusion. Surgical myocardial revascularization has a positive effect on LV diastolic function. Improvement in LV diastolic function after CABG may be a sign of the restoration of hibernating myocardium function, while the absence of LV diastolic function improvement, together with left atrial dilatation, may be predictors of early POAF.
Clinical and functional features and quality of life in depressive disorders in patients undergoing pulmonary thromboendarterectomy
Authors: Kamenskaya O. V. , Klinkova A. S. , Loginova I. Yu. , Porotnikova S. S. , Volkova I. I. , Lomivorotov V. N. , Chernyavskiy A. M. 
Published: September 2022

Aim. To conduct a comparative analysis of clinical and functional parameters and quality of life (QoL) in patients with chronic thromboembolic pulmonary hypertension (CTEPH), depending on the presence of a depressive disorder in long-term postoperative period.Material and methods. The study included 182 patients with CTEPH in the long term after surgery. Depending on the Patient Health Questionnaire 9 ( PHQ-9) data, all patients were divided into 2 groups: the 1st group — patients without depressive syndrome in the long-term postoperative period, the 2nd — patients with depressive syndrome. A comparative assessment of the initial clinical and functional characteristics, as well as QoL was carried out using the SF-36 questionnaire in both groups of patients. In patients who had a coronavirus disease 2019 (COVID-19), a comparative assessment using the Post-COVID-19 Functional Status (PCFS) scale was carried out.Results. Clinically relevant depressive syndrome in patients with CTEPH in the long term after surgery was registered in 25,3% of cases. In the 2nd group of patients, prior myocardial infarction (p=0,02), concomitant chronic cerebrovascular disease (p=0,01), as well as moderate and severe post-COVID-19 functional limitations according to the PCFS scale (p=0,004) were significantly more often recorded compared with the 1st group. In the 2nd group of patients, the level of QoL in almost all parameters was significantly lower in comparison with the 1st group (p<0,05). Decreased QoL (score <40) in the 2nd group concerned numerous parameters, including the physical and mental health components. In the 1st group of patients, reduced QoL was observed only in some physical parameters.Conclusion. The group of patients with CTEPH with depressive syndrome in the long-term postoperative period was characterized by a higher incidence of concomitant chronic cerebrovascular disease and a history of myocardial infarction compared with patients without depressive disorders. In the group of patients with depressive disorders, moderate and severe post-COVID-19 functional limitations according to the PCFS scale were more often observed. Depressive disorders in patients with CTEPH in the long-term postoperative period were accompanied by significantly reduced QoL parameters. Patients experienced the greatest difficulties both during normal daily activities and in professional activities.
Evolving Design Pedagogies: Broadening Universal Design for Social Justice
Authors: Lanteigne Victoria , Rider Traci Rose , Stratton Peter 
Published: September 2022

Universal Design came into prominence as a successor to the Americans with Disabilities Act (ADA), contributing to broader notions of accessibility beyond baseline codes and standards. Rooted in human factors research, Universal Design primarily centers on supporting human performance through the development of accessible and usable environments (Steinfeld and Maisel 2012, 95-96). As such, Universal Design pedagogies predominantly focus on enhancing environments for people with disabilities and aging populations (O Shea 2018, 721; Steinfeld and Maisel 2012, 49). However, some believe Universal Design is on the cusp of a paradigm shift to address broader aspects of social justice (Salmen 2012; Steinfeld and Maisel 2012, 159-160). This paper synthesizes existing literature to explore how current academic and practice-facing Universal Design pedagogies support the movement’s expansion to address social justice across demographic groups. Critical audiences for this work include architectural educators, students, researchers, policymakers, and building professionals interested in advancing the theory and practice of Universal Design. Recommendations from this work reposition Universal Design pedagogies as a pathway for creating more equitable and inclusive buildings, spaces, and communities that are truly designed for all.
Chemotaxonomic Significance and Environmental Implications of the Phytochemical Constituents of four Mussaenda L. (Rubiaceae) taxa in Nigeria
Authors: F.I. Nwafor , C.E. Ogbonna , U.I. Igwe , M.O. Nwosu , S.I. Inya-Agha 
Published: September 2022

This work investigated the phytoconstituents of some Mussaenda taxa (Rubiaceae) collected from Nsukka (Derived Savanna) and Uyo (Tropical Rainforest) ecological zones of Nigeria to establish their contribution as possible taxonomic and environmental monitoring markers. Fresh leaf samples used in this study were collected from plants of the same age, air-dried, and made into powder for further use. Histochemical and phytochemical tests were carried out by following the standard procedures. Results of the comparative phytochemical screening revealed the presence of flavonoids, alkaloids, glycosides, phenols, hydrogen cyanide, reducing sugars, soluble carbohydrates, saponins, steroids, terpenoids, and tannins in varying proportions. Results of the phytochemical constitute analysis revealed the presence of the cystoliths from the M. elegans (MEL) and M. erythrophylla (MER) which were absent in Mussaenda “ Doña Aurora” (MDA) and Mussaenda “Doña Luz”(MDL). Further, the presence of the Raphides was unique to MEL while Gum and mucilage were reported only in MDA. Quantitatively, MEL had the highest value of terpenoids (650.88 mg/100g) while MDA had the highest values of phenols (899.27 mg/100g), alkaloids (311.01 mg/100g), reducing sugars (967.35 mg/100g), steroids (2.89 mg/100g), soluble carbohydrates (27.68 mg/100g) and tannins (393.16 mg/100g), and MDL was richest in glucosides (339.64 mg/100g), flavonoids (69.34 mg/100g) and hydrogen cyanides (1.34 mg/100g). The cluster analysis based on obtained phytochemical data revealed three (3) distinct clusters with MEL in cluster 1; MDA and MDL in cluster 2 while cluster 3 had MER. The evolutionary closeness of the two infraspecific and exotic species (MDA and MDL) were confirmed and their taxonomic relationship with the indigenous infrageneric taxa (MEL and MER) was established. The results also highlight the opportunity of employing plant metabolomics in ecological studies and environmental monitoring.
Meningioma – A spectrum of varied case presentations: A case series
Authors: Akhtar Kafil , Sinha Dipanjan , Adil Mohammad , Aprajita  
Published: September 2022

Meningiomas are most common primary intracranial neoplasm. They arise from the arachnoid cap cells. They were previously divided into WHO grade I, grade II and grade III depending on their histological features and clinical features. However, in the new WHO 2021 updates it has been assigned a single group. Meningiomas may arise in the brain and spinal cord. An integrated approach based on clinical examination, history, radiology and histopathology aids in diagnosis. Herein we present a case series of a spectrum of clinico-pathological presentations of meningiomas. A 35-year-old female presented with headache. After clinical examination and on CT scan an intracranial lesion was noted. Craniotomy was performed and tissues examination was consistent with meningothelial meningioma. A 55-year-old female presented with pain in the limbs associated with weakness to the orthopaedics clinic. On neurological examination there was loss of power in the limbs. MRI spine revealed a round extramedullary intradural mass at T7 level. Laminectomy was done and histopathological examination showed features of Psammomatous meningioma, based on histomorphology and immunohistochemistry.A 32-year-old female presented to the Surgery clinics with dizziness and headache which was progressive and not responding to medications. MRI revealed an ovoid enhancing mass involving left parieto-occipital region, with a provisional diagnosis of meningioma. A report of Transitional meningioma was given based on histomorphology and immunohistochemistry. A 40-year-old female presented to the ophthalmic clinic with complaints of diplopia and disturbances in gait. Fundus examination revealed disc oedema and retinal vessel narrowing. MRI revealed large ovoid extra axial mass, with a provisional diagnosis of meningioma. A report of Secretory meningioma was signed out on histomorphology and immunohistochemistry.
Evaluation of esthetic parameters of the face and components of smile in children with deciduous dentition
Authors: Ganesh Chaithra , Peethambar Preetha , Konde Sapna , Agarwal Manisha , Prasad Sahana N 
Published: September 2022

In the present era, esthetics has become an important dimension in dental practice as parents and children are equally self-conscious of their appearance. Children now desire to possess an aesthetically pleasing smile. Harmonizing an esthetic smile integrates facial and dental components. Since the scientific data on pediatric esthetics are limited, the aim of the study was to evaluate esthetic parameters of the face and components of smile in children with deciduous dentition.: After fulfilling inclusion criteria, 3 sets of facial photographs of 100 children were obtained, comprising of frontal at rest, frontal smile and profile at rest images under standardised photographic technique. Linear measurements of facial and dental parameters were assessed with the help of Adobe photoshop and static norms were obtained by taking the average value. Subjective evaluation was performed by a group of professionals using Q-sort technique to list the attractive features in children.Static norms were obtained for facial and dental parameters. Attractive children showed decreased facial height, anterior lower facial height, vermilion height and bigonial width. They also displayed decreased smile index and buccal corridor ratio along with parallel smile arc and more than 3/4th of crown height visibility during smiling. Attractive children presented facial and dental parameters variable from normative values. : The study results can be utilised during restorative and prosthetic rehabilitation among children to improve esthetics.
Effectiveness of PBL in delivering image processing method to undergraduate radiography students in Puducherry, India
Authors: Tamijeselvan Sundaramoorthy 
Published: September 2022

: Problem Based Learning is an approach to learning and instruction in which students tackle problems in small groups under the supervision of a tutor. This method is very useful in imparting medical education. In this study I am going to apply PBL in the teaching of undergraduate radiography students and study the effectiveness of PBL, particularly in teaching image processing methods in radiography.: A randomized controlled design was used for the study to test the addition of Problem Based Learning (PBL) to theory lectures and clinical experience versus theory and clinical experience alone on student’s knowledge in performing Image processing in radiography. The students were randomly selected and then randomly distributed either to experimental or control group. The knowledge is accessed by valid questionnaire through the pretest and post test for both the experimental and control group. The data are then analyzed by excel work sheet to get the result.: Sixty radiography students from fourth semester were randomly assigned either to the experimental or control group, so that there were 30 students in each. The mean score for the pretest and posttest score are at 21.67 and 34.04 for experimental group with a standard deviation 4.44 and 3.44 respectively while it was 21.80 and 29.07 for the control group with a standard deviation of 3.88 and 3.85 respectively. This study shows that students' knowledge in performing image processing in radiography significantly enhanced after the application the PBL module.
Effect Of Gap Ratio On Flow Influenced Actions Of Two Circular Cylinders In Side-By-Side Arrangement
Authors: Chakraborty Sudip , Chaterjee Saikat , Kumar Ranjan 
Published: September 2022

<p>In order to understand the flow characteristics over cylinders, the investigation is required on a particular structure where interaction of fluid and solid must be there. This phenomenon is quite common in many industrial applications like transmission cables, heat exchanger tubes, cooling towers etc. Flow influenced forces can cause unwanted vibration in the structure that may cause permanent damage to the structure. In this study, one particular set up has been chosen where circular cylinders have been placed in a flow field using side-by-side arrangement in a fluid domain and the effects of the flow influenced vibration have been observed by varying the gaps between two cylinders. The entire work has been done using a CFD software based on the finite element analysis. </p>
EPIDEMIOLOGÍA DE LAS FRACTURAS DEL TOBILLO
Authors: Martínez Aparicio MD. Leonardo , Martínez Aparicio MD. Lázaro , artínez Estupiñan PhD. MD. Lázaro Martín , Jimenez Moya MD. Roberto , Ibañez Zamora MD. Ernesto 
Published: September 2022

Fundamento. Las fracturas del tobillo presentan una alta incidencia a nivel nacional, son lesiones comunes en los pacientes atendidos en la región centro norte de la provincia de Villa Clara.
Objetivo. Se realizó el presente estudio con el propósito de describir el comportamiento de las fracturas del tobillo entre el primero de enero del 2017 al 31 de diciembre del año 2020, de los pacientes atendidos en el área.
Método. Se realizó un estudio descriptivo, observacional, longitudinal y prospectivo teniendo como muestra los pacientes con fracturas del tobillo atendidos por el servicio de Ortopedia y Traumatología del Hospital Mártires del 9 de Abril, se utilizaron métodos científicos de investigación.
Resultados. Las lesiones más frecuentes se observan en los pacientes adultos, que viven en el municipio Sagua la Grande, predominan las fracturas unimaleolares, con mayor incidencia en los meses de junio y julio, con mecanismo de producción más frecuente la supinación-rotación externa, se obtienen mejores resultados y menos complicaciones con el tratamiento conservador.
Conclusión. El estudio epidemiológico permite reconocer el comportamiento de dichas lesiones y se propone medidas para la extensión a toda la provincia.
PALABRAS CLAVE. Traumatismos, fractura, tobillo.
Identification of ARG1 Mutations in Patients with Arginase 1 Deficiency
Authors: Kowsari Ali , Rafigh Mahboobeh , Kazerani Mahsa , Fakharianzadeh Saba , Sarli Abdolazim 
Published: September 2022

Introduction: Argininemia is an autosomal recessive uncommon metabolic condition, caused by mutations in arginase enzyme. Variable clinical symptoms of argininemia might bring about a delayed diagnosis. In order to prove an argininemia condition, a genetic test result is needed. This study aims to describe two cases of argininemia homozygote mutations.
Materials and Methods: Whole exome sequencing (WES) was utilized to detect disease causing variants. To prove adverse impacts of a novel variant and in silico analysis, PROVEAN web server is chosen. The effects of the novel mutation on the enzyme’s structure are shown in Chimera software using normal and mutated structures derived from SWISS model web server.
Result: WES revealed two cases of autosomal recessive hyperargininemia. In one of the patients, a homozygous missense mutation of c.491G>A was detected, which is a novel ARG1 variant (p.Trp164Ter). Bioinformatics databases and the variant’s protein structure proved its deleterious effect on the enzyme’s function. The other patient was affected by a reported mutation of c.703G>A (p.G235R).
Conclusion: The presence of various types of neurological and metabolic disorders with the same clinical findings with argininemia might lead to a lack of early diagnosis for beginning efficacious treatments. WES provides these patients with the opportunity to become diagnosed and receive therapies as early as possible.