bluuebunny/crossref_metadata_2025_split huggingface dataset:
The new discourses of nation: The origins of nationalism in late eighteenth‐century Hungary (Part 1)
Authors: Almási Gábor , Šubarić Lav 
Published: May 2022

AbstractThe main thesis of this article is that nationalist political discourses emerged in Hungary more suddenly, radically and earlier than previously thought. An underlying assumption is that nationalism may be best understood through an analysis of political discourses. The sudden appeal of these kinds of political discourses demands explanation. How did the discourses of nation overwrite earlier discourses? How did they gain social, political and cultural legitimacy? How were they related to the Enlightenment? In answering these questions, we first point to the ambiguity and fluidity of new concepts and terms, such as nation, language, fatherland, patriot and foreigner. These key concepts of nationalist discourses provided innovative and independent sources of political legitimation. They enabled the frameworks of political life and thought to be re‐established. They made for an easy entry into politics because they were rooted in familiar, earlier political discourses. However, for the success of nationalism as a political paradigm, the new discourses of nation also had to make attractive ideological offers and project positive visions of the future. These offers, as we will show, were built on an appeal to ‘public happiness’. They bound together Magyarisation and nationalism and grew from an ideology into a political programme.
Happy riders are all alike? Ambivalent subjective experience and mental well‐being of food‐delivery platform workers in China
Authors: Wu Philip F. , Zheng Ruoshu , Zhao Ying , Li Yixi 
Published: May 2022

AbstractThis study draws upon organizational psychology and platform labor research to investigate how socio‐psychological factors affect the mental well‐being of platform workers and help them cope with the challenges of work. Based on a survey study of 500 food‐delivery workers (‘riders’) in China, we provide quantitative evidence of workers' ambivalent subjective experiences that complements the predominantly qualitative account in the extant literature. In particular, we assess the complex relationships between meaningfulness of work, autonomy at work, self‐perceived competence, and workers' subjective well‐being. Our data also show that the stress‐buffering effect of social support mainly comes from the riders' familial contact and their online group chat with other workers. Overall, despite the well‐documented precarity and stress in platform work, the riders in our sample appear to be able to mobilize inner and relational resources to achieve a relatively high‐level mental well‐being.
CAN SINNERS REALLY CHANGE? UNDERSTANDING PERSONAL SALVATION IN THE BLOCK UNIVERSE
Authors: Qureshi‐Hurst Emily 
Published: May 2022

AbstractThis article brings time and theology together constructively in response to a pressing problem for the doctrine of personal salvation. The problem arises within the physics and metaphysics of time, as these support a so‐called temporal B‐theory in which time does not pass and reality is comprised of a block universe. Within this static temporal metaphysic, objective change is highly problematized. Yet salvation requires an objective change from fallenness to redemption. So, how can we understand a salvation‐transformation in the block universe? In other words, can sinners really change? I argue that on a B‐theory of time, a salvation‐transformation is best understood as a form of qualitative, phenomenological, and subjective change, rather than a robust ontological change. I conclude that the individual's transformation from fallen to saved is one of mind‐dependent becoming. So, sinners can change. But, in this lifetime, that change can only be subjective.
Co-Optimization of Supply Chain Reconfiguration and Assembly Process Planning for Factory-in-a-Box Manufacturing
Authors: Nwodu Arriana , Pasha Junayed , Jiang Zhengqian , Guo Weihong , Dulebenets Maxim , Wang Hui , Minor Kayla 
Published: May 2022

Abstract
Factory in a box (FiB) is an emerging technology that meets the dynamic and diverse market demand by carrying a factory module on vehicles to perform on-site production near customers’ locations. It is suitable for meeting time-sensitive demands, such as the outbreak of disasters or epidemics/pandemics. Compared to traditional manufacturing, FiB poses a new challenge of frequently reconfiguring supply chain networks since the final production location changes as the vehicle carrying the factory travels. Supply chain network reconfiguration involves decisions regarding whether suppliers or manufacturers can be retained in the supply chain or replaced. Such a supply chain reconfiguration problem is coupled with manufacturing process planning, which assigns tasks to each manufacturer that impacts material flow in the supply chain network. Considering the supply chain reconfigurability, this article develops a new mathematical model based on nonlinear integer programming to optimize supply chain reconfiguration and assembly planning jointly. An evolutionary algorithm (EA) is developed and customized to the joint optimization of process planning and supplier/manufacturer selection. The performance of EA is verified with a nonlinear solver for a relaxed version of the problem. A case study on producing a medical product demonstrates the methodology in guiding supply chain reconfiguration and process planning as the final production site relocates in response to local demands. The methodology can be potentially generalized to supply chain and service process planning for a mobile hospital offering on-site medical services.
9/3-Minute Running Critical Power Test: Mechanical Threshold Location With Respect to Ventilatory Thresholds and Maximum Oxygen Uptake
Authors: Ruiz-Alias Santiago A. , Olaya-Cuartero Javier , Ñancupil-Andrade Alberto A. , García-Pinillos Felipe 
Published: May 2022

Purpose: The critical power (CP) concept has been extended from cycling to the running field with the development of wearable monitoring tools. Particularly, the Stryd running power meter and its 9/3-minute CP test is very popular in the running community. Locating this mechanical threshold according to the physiological landmarks would help to define each boundary and intensity domain in the running field. Thus, this study aimed to determine the CP location concerning anaerobic threshold, respiratory compensation point (RCP), and maximum oxygen uptake (VO2max). Method: A group of 15 high-caliber athletes performed the 9/3-minute Stryd CP test and a graded exercise test in 2 different testing sessions. Results: Anaerobic threshold, RCP, and CP were located at 73% (5.41%), 86.82% (3.85%), and 88.71% (5.84%) of VO2max, respectively, with a VO2max of 66.3 (7.20) mL/kg/min. No significant differences were obtained between CP and RCP in any of its units (ie, in watts per kilogram and milliliters per kilogram per minute; P ≥ .184). Conclusions: CP and RCP represent the same boundary in high-caliber athletes. These results suggest that coaches and athletes can determine the metabolic perturbance threshold that CP and RCP represent in an easy and accessible way.
Nature-Based Early Childhood Education and Children’s Physical Activity, Sedentary Behavior, Motor Competence, and Other Physical Health Outcomes: A Mixed-Methods Systematic Review
Authors: Johnstone Avril , McCrorie Paul , Cordovil Rita , Fjørtoft Ingunn , Iivonen Susanna , Jidovtseff Boris , Lopes Frederico , Reilly John J. , Thomson Hilary , Wells Valerie , Martin Anne 
Published: May 2022

Background: The purpose was to synthesize evidence on the association between nature-based Early Childhood Education (ECE) and children’s physical activity (PA) and motor competence (MC). Methods: A literature search of 9 databases was concluded in August 2020. Studies were eligible if (1) children were aged 2–7 years old and attending ECE, (2) ECE settings integrated nature, and (3) assessed physical outcomes. Two reviewers independently screened full-text articles and assessed study quality. Synthesis was conducted using effect direction (quantitative), thematic analysis (qualitative), and combined using a results-based convergent synthesis. Results: 1370 full-text articles were screened and 39 (31 quantitative and 8 qualitative) studies were eligible; 20 quantitative studies assessed PA and 6 assessed MC. Findings indicated inconsistent associations between nature-based ECE and increased moderate to vigorous PA, and improved speed/agility and object control skills. There were positive associations between nature-based ECE and reduced sedentary time and improved balance. From the qualitative analysis, nature-based ECE affords higher intensity PA and risky play, which could improve some MC domains. The quality of 28/31 studies was weak. Conclusions: More controlled experimental designs that describe the dose and quality of nature are needed to better inform the effectiveness of nature-based ECE on PA and MC.
Prenatal Stress and Adaptive Behavior of Offspring: The Role of Placental Serotonin
Authors: Bondarenko N. S. , Voronova S. N. , Voronezhskaya E. E. , Melnikova V. I. 
Published: May 2022

Abstract
The effect of mild prenatal stress in mice, leading to an increase in the placental serotonin level, on the formation of adaptive behavior in male offspring at the age of 35 days was studied. It was shown that, in BalbC mice, daily immobilization for 1 h during the period from 11 to 14 days of pregnancy led to an increase in placental and fetal serotonin levels on the 15th day of prenatal development. According to “resident–intruder” behavioral test, the prenatally stressed mice showed more reactive behavior in adulthood and low tendency to defend their territory. Thus, placental serotonin, formed under the stress condition, may act as a mediator between the environment and the fetuses and determine the adaptive behavior of offspring.
5-Azacytidine Suppresses the Expression of Tissue-Specific Oct-1 Isoform in Namalwa Burkitt’s Lymphoma Cell Culture
Authors: Kotnova A. P. , Stepchenko A. G. , Ilyin Yu. V. , Georgieva S. G. , Pankratova E. V. 
Published: May 2022

Abstract
Overexpression of the transcription factor POU2F1 (Oct-1) increases the malignant potential of the tumor and determines the unfavorable prognosis for both solid and hematological cases of the disease in human carcinogenesis. The Oct-1 level determines the rate of development of the disease in acute myelodysplastic leukemia (AML), and a decrease in its expression significantly delays the development of leukemia in mice; however, a complete knockout of Oct-1 leads to the death of the animals. POU2F1 (Oct-1) is expressed as several isoforms transcribed from alternative promoters. They include both ubiquitous and tissue-specific isoforms. It was shown that in Burkitt’s lymphoma Namalwa cells 5-azacytidine specifically suppresses the expression of the tissue-specific isoform Oct-1L mRNA (level of Oct-1L is abnormally increased in these cells), while not causing changes in the amount of the ubiquitous isoform Oct-1A mRNA. These results show that it is possible to selectively reduce the transcription level of the Oct-1L isoform aberrantly expressed in human tumor cells.
The Emergence of a New Isoform of POU2F1 in Primates through the Use of Egoistic Mobile Genetic Elements
Authors: Lyanova B. M. , Kotnova A. P. , Makarova A. A. , Ilyin Yu. V. , Georgieva S. G. , Stepchenko A. G. , Pankratova E. V. 
Published: May 2022

Abstract
The emergence of new genes and functions is of paramount importance in the emergence of new animal species. For example, the insertion of the mobile element Tigger 2 into the sequence of the functional gene POU2F1 in primates led to the formation of a new chimeric primate-specific isoform POU2F1Z, the translation of which is activated under cellular stress. Its mRNA was found in all species of monkeys, starting with macaques. Analysis of the fragments of the Tigger2 copy corresponding to the human exon Z showed that the splicing sites of exon Z are homologous in humans and in most monkeys, with the exception of lemurs and galagos. The stop codon introduced into the mRNA by the Tigger2 sequence is present in all primates, starting with macaques. The internal ATG codon is also present in all primates, with the exception of lemurs and galagos. In the course of evolution, other MGEs, mainly of the SINE type, were inserted into the Tigger2 copy. In the course of evolution, both the location and the number of mobile SINE elements within the POU2F1 gene changed. Starting with macaques, the pattern of the arrangement of SINE elements within the Tigger2 copy in the studied region of the POU2F1 gene was fixed and then remained unchanged in other primates and humans, which may indicate its functional significance.
Effects of CIK Cell Therapy Combined with Camrelizumab on the Quality of Life in Patients with Nasopharyngeal Carcinoma and Analysis of Prognostic Factors
Authors: Feng Tao , Luo Xiu , Cao Wenping , Man Rongjun , Feng Xinrong , Song Yujie 
Published: May 2022

Objective. To investigate the effects of CIK (cytokine-induced killer) cell therapy combined with camrelizumab on the quality of life in patients with nasopharyngeal carcinoma and prognostic factors. Methods. In this retrospective study, the materials of 80 patients with nasopharyngeal carcinoma treated in our hospital (February 2017–February 2019) were retrospectively analyzed, and they were equalized into experimental group (n = 40) and control group (n = 40) according to the order of admission. Both groups received 200 mg of camrelizumab on day 1 combined with 10 mg of anrotinib from day 2 to day 4. The patients received the above program every 3 weeks and 4 treatment cycles. The experimental group also received CIK cell therapy simultaneously. The patients’ quality of life, immune indexes, local control, metastasis, and survival rate were compared between the two groups, and the prognostic factors were analyzed by logistic analysis. Results. Compared with the control group, the experimental group achieved much higher scores of physical well-being (18.38 ± 2.31), social/family well-being (16.40 ± 2.24), emotional well-being (15.35 ± 2.30), functional well-being (17.30 ± 2.20), and head and neck cancer subscale (15.40 ± 2.01,

P

< 0.001) and eminently better immune indexes (

P

< 0.001) after treatment. During the 24-month follow-up, there were 2 recurrent cases (5.0%) and 2 cases (5.0%) with distant metastasis among the 40 patients in the experimental group; there were 8 recurrent cases (20.0%) and 7 cases (17.5%) with distant metastasis among the 40 patients in the control group. In the experimental group, the median survival period was 18 months and the 2-year survival rate was 97.5% (39/40). In the control group, the median survival period was 14 months and the 2-year survival rate was 85.0% (34/40). Among the 80 patients, 7 cases (8.75%) died and 73 cases (91.25%) survived. After conducting the single-factor analysis, remarkable differences in the cases of IV stage, quality of life after treatment, and immune indexes after treatment between the survival group and the death group were observed (

P

< 0.05). According to the multiple-factor analysis, the clinical stage and immune indexes were identified as the prognostic factors. Conclusion. CIK cell therapy combined with camrelizumab can enhance the life quality and immune function of the patients with nasopharyngeal carcinoma, thus improving their prognoses.
The Influence of Obesity on Small Bowel Capsule Endoscopy
Authors: Omori Teppei , Sasaki Yu , Koroku Miki , Kambayashi Harutaka , Murasugi Shun , Yonezawa Maria , Nakamura Shinichi , Tokushige Katsutoshi 
Published: May 2022

Objective. Intestinal motility may be different in obese and nonobese patients, but this has not been determined. Here, we sought to evaluate the effect of obesity on small bowel capsule endoscopy (SBCE). Patients and Methods. We retrospectively analyzed the cases of the 340 patients who underwent SBCE for small intestinal disease (excluding cases of unobservable total small bowel, small bowel stenosis, and bowel resection) at our hospital during the period January 2014 to December 2020 to extract patient background factors and the bowel transit times of SBCE according to the presence/absence of obesity (defined as a

body

mass

index

BMI

≥
25

kg
/

m

2

). Results. The obese group was 54 patients (nonobese,

n
=
286

). The small bowel transit time (SBTT) was significantly shorter in the obese patients compared to the nonobese patients (

p
=
0.0026

), and when we divided the patients by their short/long SBTTs using 216.5 min as the cutoff, we observed significant between-group differences in the patients’ age (≥60 years) and in the patients’ hospitalization status at the time of the SBCE examination. A multivariate analysis revealed that hospitalized status at the examination is a factor contributing significantly to a long SBTT (OR 0.25, 95% CI: 0.15–0.42,

p
<
0.0001

). An analysis using the outpatient/inpatient conditions showed that obesity was an independent factor in the inpatient status at the SBCE examination with a significant short SBTT (OR 2.91, 95% CI: 1.06–7.97,

p
=
0.0380

). Constipation at the examination was also a factor contributing to a long SBTT (OR 0.26, 95% CI: 0.07–0.99,

p
=
0.0493

). Conclusion. The SBTT of the SBCE was significantly shorter in the obese patients. This tendency was especially evident in the hospitalized state.
Effect of SQ3R on Students’ Reading Comprehension
Authors: Cataraja Geryl 
Published: May 2022

Comprehension is the primary objective reading, which promotes cognizance in all disciplines and so improves the teaching-learning process. The objective of this research was to see how SQ3R affected the reading comprehension of Grade 11 students at the Palompon Institute of Technology. The pretest-posttest control group design was employed in this research. Sixty Students randomly assigned to either of the groups. To gather the data, a reading comprehension test was used. It was treated using the mean and t-tests for dependent and independent samples. The following findings were revealed: 1) The initial reading comprehension of the SQ3R was “fair to good” while the conventional reading strategy was also “fair to good.” 2) The students’ initial reading comprehension was of the same level; 3)The final reading comprehension of the SQ3R was better than the conventional reading strategy ; 4) A significant difference was found between the initial and final reading comprehension of the students exposed to the SQ3R as well as those to the conventional reading strategy; and 5) There was a significant difference between the reading comprehension of the students exposed to the SQ3R and to the conventional reading strategy. This means that the SQ3R is a more effective strategy than conventional reading in the development of the students’ reading comprehension. On the above findings, it was concluded that students need a different reading strategy to improve their reading comprehension, but they perform better if they use the SQ3R instead of conventional reading strategy.
Gender – Fair Language in Teaching Basic Education
Authors: Gamboa Jerame N. , Bacani Michael Angelo , Baluyut Jennifer , Galura Olive N. , Manalastas Kristine E. 
Published: May 2022

Education aims to create equality and respect through its components. One of those components is the learning delivery of any subject matter wherein language is mainly utilized. The study aimed to determine the usage of the gender sensitive language in teaching basic education at Don Honorio Ventura State University. It specifically sought to answer on the level of familiarity of the teachers on the gender-fair language; the frequency on the teacher’s usage of the gender-fair language; the common gender-fair terminologies used in motivation, discussion, performance tasks, assessments, and assignments; and the difficulties that the teachers encountered in using gender-fair language. The study used sequential explanatory type of research. It used questionnaires and interviews in gathering data. There are 65 participants who answered the survey and 11 of them participated in the focal group discussion. Based on the findings, the teachers are familiar with the gender-fair language but they sometimes use them in various areas of teaching such as in motivation, discussion, performance task, assessment, and assignment due to the topic pertinence and student ability. With those findings, the conduct of wide dissemination through capability building on the use of gender-fair language is still needed.
Towards a Better Distance Learning: Experience of Radiologic Technology Students in a Higher Education Institution
Authors: Said Mariam Hadji , Dalug Normylene , Galawan Nihayah , Hibaya Harold Jay , Jenan Jenan 
Published: May 2022

Radiologic Technology students are among those who felt the intensity of drastic changes brought by the pandemic in education, particularly when distance learning was utilized. The main objective of this study is to find out the varied experiences of the selected students and find out the necessary measures that need to be taken to address the emerging issues that surround distance learning. This phenomenological qualitative research was done by interviewing the selected respondents from Iligan Medical Center College, transcribing their answers, and utilizing thematic analysis to find out the recurring themes. The respondents of this research were the eight selected students, who were enrolled in Radiologic Technology program. There were two respondents taken from each year level and interviewed online. The responses taken from the interview transcripts were grouped and labelled according to their semantic similarities. The researchers found out that the current distance learning practices of Iligan Medical Center College include online-synchronous and online-asynchronous learning. The students’ main problems regarding this type of education include their teachers’ lack of knowledge on technology utilization, financial constraints, internet connection problems, lack of focus on their lessons, their vulnerability to cheating, and the health issues and problems. Moreover, the coping strategies of the students to the problems they encounter in distance learning include time-management and getting support from the significant persons around them. In addition, the students assert that the school administration should monitor the teachers even more and improve their digital skills in order for them to relay the lessons more efficiently and effectively. Furthermore, they also emphasized that the teachers’ discussion should be livelier in order to encourage active learning and that they should be more considerate and patient, especially when the students try to approach them for something that they did not understand. In addition, the students also believed that the teachers should practice more in using their technological resources. Generally, data from this research imply that the distance learning will be even more successful if there is a proper preparation and training for both the teachers and students. Also, there should be an intervention program that will help the students in dealing with their mental and health issues.