bluuebunny/crossref_metadata_2025_split huggingface dataset:
US Communists as Early Social Movement Unionists Circa 1930 to 1956?
Authors: Devinatz Victor G. 
Published: July 2022

Abstract
Through the examination of three recently published volumes, in this review essay I argue that US Communists were “premature social movement unionists” in the quarter century circa 1930 to 1956. US Communists had adopted social movement unionism (smu), which did not officially emerge as an accepted type of trade unionism until the late 1980s/early 1990s, approximately a half century before becoming accepted throughout the world. This demonstrates that US Communists recognized the enormous potential of what trade unionism could achieve beyond the American Federation of Labor’s craft-oriented business unionism and the Industrial Workers of the World’s shopfloor based revolutionary syndicalism. Thus, the Communists’ smu can be interpreted as a precursor to the twenty-first century Bargaining for the Common Good.
Goals, Models, and Practices of International Partnerships in Higher Education: Toward Global Peace and Harmony
Authors: Ma Liwen , Subbiondo Joseph L. 
Published: July 2022

Abstract
This paper is focused on a variety of approaches and paths to increase and advance international education partnerships. It studies methods in general considering their theoretical frameworks as well as their aspirations, goals, and outcomes. It also presents exemplary models currently used in Eastern and Western higher education that are largely applicable to most universities. The paper also notes areas of impact that international education partnerships can have on teaching， learning, and research because of national educational differences, multi-cultural perspectives, and global interconnectedness. In addition, it highlights two exemplary models of international education partnerships at Beijing Normal University. Throughout, the paper references essays included in this special issue as well as elsewhere. The underlying theme in this essay and the special issue is that universities contribute to the integrity of education as well as global peace by increasing, updating, and assessing international education partnerships that facilitate meaningful global interactions and shared learning among faculty, students, and universities.
Netflix Turkey’s Ethos and the Contradictions of Global Streaming Television
Authors: Marcus Matthew 
Published: July 2022

Abstract
The mini-series Ethos (Bir Başkadir), produced by Netflix Turkey, was a critical and social media sensation, distinguished by its narrative and visual sophistication and its explicit engagement with contemporary social, cultural and political tensions. However, considered in light of larger questions about Netflix and streaming television in general, Ethos also provides a meta-commentary on contradictory aspects of streaming television, particularly those discussed by Ramon Lobato in his book Netflix Nations. In particular, Ethos self-consciously calls attention to ways in which it is simultaneously a local and transnational product. It also invites consideration of the divergent expectations and responses of its varied audiences, both in Turkey and abroad.
Independent Quality Assessment of Essential Climate Variables: Lessons Learned from the Copernicus Climate Change Service
Authors: Yang Chunxue , Cagnazzo Chiara , Artale Vincenzo , Buongiorno Nardelli Bruno , Buontempo Carlo , Busatto Jacopo , Caporaso Luca , Cesarini Claudia , Cionni Irene , Coll John , Crezee Bas , Cristofanelli Paolo , de Toma Vincenzo , Essa Yassmin Hesham , Eyring Veronika , Fierli Federico , Grant Luke , Hassler Birgit , Hirschi Martin , Huybrechts Philippe , Le Merle Eva , Leonelli Francesca Elisa , Lin Xia , Madonna Fabio , Mason Evan , Massonnet François , Marcos Marta , Marullo Salvatore , Müller Benjamin , Obregon Andre , Organelli Emanuele , Palacz Artur , Pascual Ananda , Pisano Andrea , Putero Davide , Rana Arun , Sánchez-Román Antonio , Seneviratne Sonia I. , Serva Federico , Storto Andrea , Thiery Wim , Throne Peter , Van Tricht Lander , Verhaegen Yoni , Volpe Gianluca , Santoleri Rosalia 
Published: July 2022

Abstract
If climate services are to lead to effective use of climate information in decision-making to enable the transition to a climate-smart, climate-ready world, then the question of trust in the products and services is of paramount importance. The Copernicus Climate Change Service (C3S) has been actively grappling with how to build such trust: provision of demonstrably independent assessments of the quality of products, which was deemed an important element in such trust-building processes. C3S provides access to essential climate variables (ECVs) from multiple sources to a broad set of users ranging from scientists to private companies and decision-makers. Here we outline the approach ­undertaken to coherently assess the quality of a suite of observation- and reanalysis-based ECV products covering the atmosphere, ocean, land, and cryosphere. The assessment is based on four pillars: basic data checks, maturity of the datasets, fitness for purpose (scientific use cases and climate studies), and guidance to users. It is undertaken independently by scientific experts and presented alongside the datasets in a fully traceable, replicable, and transparent manner. The methodology deployed is detailed, and example assessments are given. These independent scientific quality assessments are intended to guide users to ensure they use tools and datasets that are fit for purpose to answer their specific needs rather than simply use the first product they alight on. This is the first such effort to develop and apply an assessment framework consistently to all ECVs. Lessons learned and future perspectives are outlined to potentially improve future assessment activities and thus climate services.
Artificial Intelligence and Laryngeal Cancer: From Screening to Prognosis: A State of the Art Review
Authors: Bensoussan Yael , Vanstrum Erik B. , Johns Michael M. , Rameau Anaïs 
Published: July 2022

AbstractObjectiveThis state of the art review aims to examine contemporary advances in applications of artificial intelligence (AI) to the screening, detection, management, and prognostication of laryngeal cancer (LC).Data SourcesFour bibliographic databases were searched: PubMed, EMBASE, Cochrane, and IEEE.Review MethodsA structured review of the current literature (up to January 2022) was performed. Search terms related to topics of AI in LC were identified and queried by 2 independent reviewers. Citations of selected studies and review articles were also evaluated to ensure comprehensiveness.ConclusionsAI applications in LC have encompassed a variety of data modalities, including radiomics, genomics, acoustics, clinical data, and videomics, to support screening, diagnosis, therapeutic decision making, and prognosis. However, most studies remain at the proof‐of‐concept level, as AI algorithms are trained on single‐institution databases with limited data sets and a single data modality.Implications for PracticeAI algorithms in LC will need to be trained on large multi‐institutional data sets and integrate multimodal data for optimal performance and clinical utility from screening to prognosis. Out of the data types reviewed, genomics has the most potential to provide generalizable models thanks to available large multi‐institutional open access genomic data sets. Voice acoustic data represent an inexpensive and accurate biomarker, which is easy and noninvasive to capture, offering a unique opportunity for screening and monitoring of LA, especially in low‐resource settings.
Predictors and prognostic significance of persistent fluid overload: A longitudinal study in Chinese peritoneal dialysis patients
Authors: Ng Jack Kit-Chung , Kwan Bonnie Ching-Ha , Chan Gordon Chun-Kau , Chow Kai Ming , Pang Wing Fai , Cheng Phyllis Mei-Shan , Leung Chi Bon , Li Philip Kam-Tao , Szeto Cheuk Chun 
Published: July 2022

Background: Cross-sectional studies showed that fluid overload (FO) measured by bioimpedance spectroscopy (BIS) predicted adverse outcomes in patients on peritoneal dialysis (PD). We aimed to describe the longitudinal change in volume status in Chinese PD patients and determine its relation with clinical outcomes. Methods: We performed a single-centre, retrospective analysis of all PD patients who underwent repeated BIS from 2010 to 2015. FO was defined by relative hydration index (RHI; volume of overhydration adjusted by extracellular water >7%). Variability of volume status (VVS) was denoted by the standard deviation of all RHI. The association of time-averaged RHI and VVS on patient and technique survival was explored by a competing risk model. Results: A total of 269 patients were followed for a median of 47.1 months. Mean time-averaged RHI was 17.6 ± 10.2%. Multivariable mixed linear regression revealed that RHI was significantly associated with diabetes, time-varying systolic blood pressure, and inversely with time-varying albumin level, lean tissue index and fat tissue index ( p <0.0001 for all). Time-averaged RHI independently predicted patient survival (subdistribution hazard ratio (SHR) 1.05, 95% CI 1.03–1.07, p <0.0001) and technique survival (SHR 1.04, 95% CI 1.02–1.06, p <0.0001), whereas VVS did not. The mortality risk for patients with persistent FO was consistently higher than the corresponding risk estimated from baseline FO of the same extent. Conclusions: Persistent FO was a strong predictor of patient and technique failure. Repeated bioimpedance measurements to monitor volume status may provide additional prognostic information in PD patients.
Ectopic and impacted maxillary canines: A quality evaluation of online information
Authors: Meade Maurice J , Dreyer Craig W 
Published: July 2022

Objective: To determine the quality of online information regarding ectopic and impacted maxillary canines (EIMCs). Design: A cross-sectional survey on the Internet. Material and methods: An online search using eight terms was carried out using four search engines. The relevant content of websites satisfying the inclusion and exclusion criteria were assessed for quality by applying three quality of information instruments and one readability tool. Statistical analyses were performed through GraphPad Prism 9.0. Results: In total, 77 websites were evaluated. Most of the assessed content was associated with oral and maxillofacial surgery (49.35%) and orthodontic websites (31.18%). The overall mean DISCERN score was 38.05 ± 9.76/80 with 59.73% of websites recording a poor or very poor score. Three (3.9%) websites contained the HONCode seal. Twelve (15.58%) websites satisfied at least three out of a maximum four JAMA benchmarks and 11 (14.29%) satisfied none. The mean SMOG score was 9.81 ± 1.52 (95% confidence interval = 9.46–10.16; range = 6.7–15.1). Conclusion: The quality of online information related to EIMCs was poor and the content was difficult to read. Professional societies and clinicians should consider the use of quality of information and readability tools to enable the provision for reliable, high-quality and readable online information. This will assist EIMC treatment-related decision-making and management by patients and their families.
The Effectiveness of Superbolus on Postprandial Blood Glucose Management of Pregnant Women With Type 1 Diabetes
Authors: Pintaudi Basilio , Gironi Ilaria , Mion Elena , Di Vieste Giacoma , Meneghini Elena , Disoteo Olga , Pani Arianna , Bonomo Matteo , Bertuzzi Federico 
Published: July 2022

Aim: Pregnancies of women with pregestational diabetes are at risk of after-meal glucose peaks and late after-meal hypoglycemia, particularly at breakfast. We aimed to explore the effectiveness of a specific feature of insulin pump therapy called superbolus in preventing these glucose swings. Methods: In this retrospective observational study, we analyzed continuous glucose monitoring data of patients with type 1 diabetes in pregnancy who were advised to use superbolus to manage their breakfast. Some of the postprandial basal insulin delivery was partially reduced and delivered instead as additional insulin bolus on top of a normal bolus. Outcomes of interest were one hour after breakfast glucose levels, the time in glucose range for after breakfast period, the number of late hypoglycemic episodes. Results: Overall, 21 consecutive pregnant women with type 1 diabetes (mean age 34.3 ± 5.5 years, mean pregestational body mass index 23.7 ± 4.7 kg/m2, HbA1c levels during pregnancy 6.1 ± 0.6%) were studied. Superbolus reduced after breakfast glucose peaks (one hour after breakfast glucose levels 130 ± 17 mg/dL vs 123 ± 10 mg/dL before and after superbolus use, respectively, P = .01), improved the time in glucose range for after breakfast period (70.4% vs 50.8%, P = .001), and reduced the number of late hypoglycemic episodes (3 [1-5] vs 1 [0-2], P< .0001). Conclusion: Superbolus was effective in avoiding after-meal glucose peaks, increased postprandial glucose time in target, without late hypoglycemia occurrence. It represents a valid option for the treatment of pregnant women with type 1 diabetes using insulin pump.
Stress Resilience Program for Health Care Professionals During a Pandemic: A Pilot Program
Authors: Croghan Ivana T. , Hurt Ryan T. , Fokken Shawn C. , Fischer Karen M. , Lindeen Stephanie A. , Schroeder Darrell R. , Ganesh Ravindra , Ghosh Karthik , Bausek Nina , Bauer Brent A. 
Published: July 2022

Background: The COVID-19 pandemic has led to increased burnout and staff turnover for health care providers (HCPs). The purpose of this pilot study was to evaluate the safety and acceptability of a Stress Resilience Program (SRP) for reducing perceived stress and improving resilience among HCPs during a pandemic. Method: Of the 12 HCPs expressing interest in the study, 10 were enrolled in this study. Participants attended three in-person visits (consent/screen, baseline, and end-of-study). The SRP consisted of education related to resilience enhancement and a breathing device ( BreatherFit®) for combined respiratory muscle training (cRMT). Participants completed 4 weeks of cRMT and applied situational breathing strategies as needed. Outcomes measured were changes in stress (PSS-10), resilience (BRS), depression (PRIME-MD), and sleep (PSQI and Ōura Ring®). Findings: The majority of participants were male (60%) and White (60%) with an average age of 39.7 years. Changes from baseline to end-of-treatment indicated a positive trend with significant stress reduction (−3.2 ± 3.9, p = .028) and nonsignificant depression reduction (−0.5 ± 0.7, p = .05). Resilience was high at baseline and continued to stay high during the study with a nonsignificant increase at end-of-study (+0.07 ± 0.7, p = .77). No changes in overall sleep scores were noted. All participants agreed the study was worthwhile, 80% indicated they would repeat the experience, while 90% indicated they would recommend the study to others. Conclusion/Application to Practice: Because of its size and portability, SRP is an easily applicable and promising option for reducing stress among HCPs during a high-stress period, such as a pandemic. Larger studies are needed.
High early death rates, treatment resistance, and short survival of Black adolescents and young adults with AML
Authors: Larkin Karilyn T. , Nicolet Deedra , Kelly Benjamin J. , Mrózek Krzysztof , LaHaye Stephanie , Miller Katherine E. , Wijeratne Saranga , Wheeler Gregory , Kohlschmidt Jessica , Blachly James S. , Mims Alice S. , Walker Christopher J. , Oakes Christopher C. , Orwick Shelley , Boateng Isaiah , Buss Jill , Heyrosa Adrienne , Desai Helee , Carroll Andrew J. , Blum William , Powell Bayard L. , Kolitz Jonathan E. , Moore Joseph O. , Mayer Robert J. , Larson Richard A. , Stone Richard M. , Paskett Electra D. , Byrd John C. , Mardis Elaine R. , Eisfeld Ann-Kathrin 
Published: July 2022

Abstract
Survival of patients with acute myeloid leukemia (AML) is inversely associated with age, but the impact of race on outcomes of adolescent and young adult (AYA; range, 18-39 years) patients is unknown. We compared survival of 89 non-Hispanic Black and 566 non-Hispanic White AYA patients with AML treated on frontline Cancer and Leukemia Group B/Alliance for Clinical Trials in Oncology protocols. Samples of 327 patients (50 Black and 277 White) were analyzed via targeted sequencing. Integrated genomic profiling was performed on select longitudinal samples. Black patients had worse outcomes, especially those aged 18 to 29 years, who had a higher early death rate (16% vs 3%; P=.002), lower complete remission rate (66% vs 83%; P=.01), and decreased overall survival (OS; 5-year rates: 22% vs 51%; P&lt;.001) compared with White patients. Survival disparities persisted across cytogenetic groups: Black patients aged 18 to 29 years with non–core-binding factor (CBF)-AML had worse OS than White patients (5-year rates: 12% vs 44%; P&lt;.001), including patients with cytogenetically normal AML (13% vs 50%; P&lt;.003). Genetic features differed, including lower frequencies of normal karyotypes and NPM1 and biallelic CEBPA mutations, and higher frequencies of CBF rearrangements and ASXL1, BCOR, and KRAS mutations in Black patients. Integrated genomic analysis identified both known and novel somatic variants, and relative clonal stability at relapse. Reduced response rates to induction chemotherapy and leukemic clone persistence suggest a need for different treatment intensities and/or modalities in Black AYA patients with AML. Higher early death rates suggest a delay in diagnosis and treatment, calling for systematic changes to patient care.
Quantitative proteomics reveals protein dysregulation during T cell activation in multiple sclerosis patients compared to healthy controls
Authors: Cappelletti Chiara , Eriksson Anna , Brorson Ina Skaara , Leikfoss Ingvild S. , Kråbøl Oda , Høgestøl Einar August , Vitelli Valeria , Mjaavatten Olav , Harbo Hanne F. , Berven Frode , Bos Steffan D. , Berge Tone 
Published: July 2022

Abstract
Background
Multiple sclerosis (MS) is an autoimmune, neurodegenerative disorder with a strong genetic component that acts in a complex interaction with environmental factors for disease development. CD4+ T cells are pivotal players in MS pathogenesis, where peripherally activated T cells migrate to the central nervous system leading to demyelination and axonal degeneration. Through a proteomic approach, we aim at identifying dysregulated pathways in activated T cells from MS patients as compared to healthy controls.

Methods
CD4+ T cells were purified from peripheral blood from MS patients and healthy controls by magnetic separation. Cells were left unstimulated or stimulated in vitro through the TCR and costimulatory CD28 receptor for 24 h prior to sampling. Electrospray liquid chromatography-tandem mass spectrometry was used to measure protein abundances.

Results
Upon T cell activation the abundance of 1801 proteins was changed. Among these proteins, we observed an enrichment of proteins expressed by MS-susceptibility genes. When comparing protein abundances in T cell samples from healthy controls and MS patients, 18 and 33 proteins were differentially expressed in unstimulated and stimulated CD4+ T cells, respectively. Moreover, 353 and 304 proteins were identified as proteins exclusively induced upon T cell activation in healthy controls and MS patients, respectively and dysregulation of the Nur77 pathway was observed only in samples from MS patients.

Conclusions
Our study highlights the importance of CD4+ T cell activation for MS, as proteins that change in abundance upon T cell activation are enriched for proteins encoded by MS susceptibility genes. The results provide evidence for proteomic disturbances in T cell activation in MS, and pinpoint to dysregulation of the Nur77 pathway, a biological pathway known to limit aberrant effector T cell responses.
Later one knows better: the over-reporting of short-time work in firm surveys
Authors: Kagerl Christian , Schierholz Malte , Fitzenberger Bernd 
Published: July 2022

AbstractShort-time work (STW) in Germany allows for a lot of flexibility in actual usage. Ex ante, firms notify the Employment Agency about the total number of employees eligible, and, up to the total granted, firms can flexibly choose how many employees actually use STW. In firm-level surveys, which provide timely information on STW in Germany, over-reporting of the number of employees on STW is prevalent. This study explores reasons for STW over-reporting based on a high-frequency and low-cost survey initiated during the Covid-19-pandemic (BeCovid) and a low-frequency and high-cost long-running survey (BP). Merging administrative records on actual use of STW, firms that use STW prove more likely to participate in the BeCovid survey. Multi-establishment firms over-report STW because they tend to report STW for all subfirms. The BP uses more interview time and confirms the over-reporting of STW use in the survey month, while—crucially—the over-reporting drops sharply with a few months of retrospection.
Fecal microbiota and their association with heat stress in Bos taurus
Authors: Czech Bartosz , Szyda Joanna , Wang Kai , Luo Hanpeng , Wang Yachun 
Published: July 2022

Abstract
Background
Humans have been influencing climate changes by burning fossil fuels, farming livestock, and cutting down rainforests, which has led to global temperature rise. This problem of global warming affects animals by causing heat stress, which negatively affects their health, biological functions, and reproduction. On the molecular level, it has been proved that heat stress changes the expression level of genes and therefore causes changes in proteome and metabolome. The importance of a microbiome in many studies showed that it is considered as individuals’ “second genome”. Physiological changes caused by heat stress may impact the microbiome composition.

Results
In this study, we identified fecal microbiota associated with heat stress that was quantified by three metrics – rectal temperature, drooling, and respiratory scores represented by their Estimated Breeding Values. We analyzed the microbiota from 136 fecal samples of Chinese Holstein cows through a 16S rRNA gene sequencing approach. Statistical modeling was performed using a negative binomial regression. The analysis revealed the total number of 24 genera and 12 phyla associated with heat stress metrics. Rhizobium and Pseudobutyrivibrio turned out to be the most significant genera, while Acidobacteria and Gemmatimonadetes were the most significant phyla. Phylogenetic analysis revealed that three heat stress indicators quantify different metabolic ways of animals’ reaction to heat stress. Other studies already identified that those genera had significantly increased abundance in mice exposed to stressor-induced changes.

Conclusions
This study provides insights into the analysis of microbiome composition in cattle using heat stress measured as a continuous variable. The bacteria highly associated with heat stress were highlighted and can be used as biomarkers in further microbiological studies.