bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Back of Queue at Signalized Intersections in Erbil City Using Different Software
Authors: Omar Dilveen H. , Hussein Salar K. 
Published: November 2022

Aims:
The aim of this study is to evaluate the queue length of isolated signalized intersections, which used HCS2010 and SIDRA Intersection 8 traffic software.

Background:
One of the important parameters to evaluate the performance of a traffic management system is queue length, especially in congested traffic situations. For the estimation of back of queue length, many traffic analyzing models are used based on Highway Capacity Manual (HCM2010).

Objective:
The values of queue length obtained from these two softwares are to be compared with observed queue length from the field. The study also aids in conducting a model of optimization for the back of queue length to decrease the value of storage length of vehicles following the GA procedure.

Methods:
In this study, four isolated signalized intersections were used in Erbil city, the capital of the Iraqi Kurdistan Region. The values of the measured back of queue lengths are compared with the values obtained from Highway Capacity Software HCS2010(HCS+T7F) and Signalized and Unsignalized Intersection Design and Research (SIDRA Intersection 8) Aid Australian Road Research Board (ARRB) software.

Results and Discussion:
The results of regression analysis showed that the SIDRA Intersection 8 Back of Queue model with adjusted R2 0.8465 have a stronger relationship with the field measured Back of the Queue for linear relationship compared to the HCS2010 back of queue model. Furthermore, the study tends to optimize the signalized intersections under study using HCS2010 and SIDRA Intersection 8 software based on the Genetic Algorithm (GA) to minimize the back of queue length. The percent of average reduction in HCS2010 and SIDRA Intersection 8 back of queue models are 36% and 29%, respectively. The main objective of optimizing the timing plan was to minimize the average storage queue length at signalized intersections that follow the Highway Capacity Manual (TRB 2010) procedure for queue length calculation. Moreover, 95th and 98th values of the percentiles were chosen to estimate the expectancy of upstream lane blockage and the expectancy of short lane overflow that was related to the back of the queue percentile.

Conclusion:
The improvement of vehicle storage for upstream lanes was conducted by the two software systems mentioned before. The results showed significant improvement in the performance of the intersections under study with a reduction in queue length.
Evaluation in Terms of Dosimetry and Fertility of F18-FDG and Ga68- PSMA in Prostate Cancer Imaging: A Simulation with GATE
Authors: Kökkülünk Handan Tanyildizi , Yildirim Ayşe Karadeniz 
Published: November 2022

Introduction:F18 and Ga68 radioisotopes are used in PET imaging for prostate cancer. It was aimed to calculate the prostate, testicle and bladder effective doses (ED) caused by F18 and Ga68 used in prostate cancer imaging with PET/CT via simulation with the GATE toolkit and evaluate the ED in terms of fertility.Methods:The prostate, testicle and bladder were defined together with their geometric properties and densities in GATE simulation. F18 and Ga68 with activity of 277.5 MBq and 151.7 MBq were identified in the prostate as a source organ. The ED, uncertainties, and S values were taken as an output file in the TXT format with the DoseActors command. S values were used for validation of the simulation.Results:The ED of the prostate, total testicle and bladder for F18 were found to be 6.627E-04 ± 1.799E-06, 12.74E-07 ± 4.11E-08 and 1.617E-05 ± 4.317E-09 (Gy/s), respectively. The ED of the prostate, total testicle, and bladder for Ga68 were found to be 9.195E-04 ± 2.660E-06, 6.54E-07 ± 2.93E-08 and 4.290E-05 ± 6.936E-09 (Gy/s), respectively.Conclusions:It was found that Ga68 produced high prostate and bladder ED, and F18 produced high testicular ED. In terms of male fertility, Ga68 seems to be a good alternative because it produces low testicular doses. The ED of the testicle both F18 and Ga68 were below the reported spermatogonia and azoospermia dose.
Smartpaddle® as a New Tool for Monitoring Swimmers’ Kinematic and Kinetic Variables in Real Time
Authors: Marinho Daniel A. , Barbosa Tiago M. , Auvinen Ari , Lopes Tiago , Silva António J. , Morais Jorge E. 
Published: November 2022

Background:
Smart technology, such as wearables, applied to sports analysis is essential for performance enhancement. New technological equipment can promote the interaction between researchers, coaches, and athletes, facilitating information exchange in real time.

Objective:
The aim of this study was to present new wearable equipment (SmartPaddle®) to measure kinematic and kinetic variables in swimming and understand the agreement of the propulsive force variable with a pressure sensor system.

Methods:
Four male university swimmers (18.75±0.50 years old, 71.55±6.80 kg of body mass, and 175.00±5.94 cm of height) were analyzed. The SmartPaddle® and a pressure sensor system were used to collect the kinetic data (propulsive force). The comparison between the propulsive force methods was based on t-test paired samples, simple linear regression, and Bland-Altman plots.

Results:
SmartPaddle® is a system that consists of (i) a wearable device, (ii) the Trainesense Session Manager mobile application for recording, and; (iii) the Analysis Center for analysis and data storage. It records a set of kinematic and kinetic parameters useful for coaches daily. The comparison between the different methods revealed non-significant differences and a very-high relationship.

Conclusion:
SmartPaddle® is a feasible wearable device that swimmersswimmers can use can use to provide immediate data about their kinematic and kinetic profile. Coaches can easily monitor these parameters and give immediate suggestions to their swimmers on a daily basis.
Predictors of Physical Educators' Attitudes toward including Students with Disabilities in Inclusive Classes
Authors: Alhumaid Majed M. 
Published: November 2022

Background:In recent years, inclusion has become an educational system implemented in many countries of the world, and teachers' attitudes towards this system are considered one of the most important factors to ensure its success.Objective:The purpose of this study was to examine Saudi Arabian physical educators’ attitudes toward teaching students with disabilities in inclusive physical education settings, and to examine the factors that affect such attitudes.Methods:Physical educators’ attitudes (N = 1,303; Mage= 40.07; SD = 9.30) were measured using the Arabic version of the Sentiments, Attitudes and Concerns about Inclusive Education-Revised Scale (SACIE-R).Results:Despite the moderately positive attitudes developed by physical educators, females reported more positive attitudes toward inclusion than males (2.51± 0.39vs. 2.345 ± 0.36; Z = -8.545; p = 0.001). Regression analysis indicated that three personal factors (i.e., gender, previous participation in training courses to teach students with disabilities, and knowledge of the Saudi educational legislation or policy) were significant predictors of physical educators’ attitudes toward such inclusion.Conclusion:The findings provide a database that Saudi Arabian educational decision-makers can refer to when designing teacher preparation programs in universities and educational institutions.
Medicinal Plants as Natural Anti-Parasitic Agents Against Blastocystis Species
Authors: Mostafa El-Sayed Nagwa , Gamal Masoud Nagham 
Published: November 2022

Background:Blastocystis species (sp.) are enteric parasites that live in both humans' and animals' gastrointestinal tracts. Blastocystis hominis (B. hominis) is the recognizable human isolates in clinical and diagnostic specimens. Human infection occurs via the oro-fecal route, particularly in developing areas due to the lack of sanitation and hygienic facilities. B. hominis can exist in the large intestine for weeks to years until treated appropriately. Metronidazole is the drug of choice for the treatment of Blastocystis infection. However, it induces intolerable side effects and has been shown to have teratogenic and carcinogenic potential. Several medicinal plant extracts have been experimentally tested against Blastocystis infection in comparison to currently available treatments.Objective:Based on in vitro and in vivo studies, this article reviewed anti-Blastocystis activity of some medicinal plants.Method:To conduct the research for this review, Google Scholar and PubMed were the primary search engines used to find relevant literature. A total of 19 published in vitro and in vivo studies were evaluated to identify the anti-Blastocystis effects of various medicinal plantsResults:Multiplication of Blastocystis parasites as well as nucleic acids and protein synthesis, all be inhibited by extracts from different medicinal plants. These natural agents have been shown to be both safe and effective when compared to the existing treatment options.Conclusion:Different medicinal plants can combat Blastocystis infection and could be a good substitute for metronidazole and other synthetic treatments.
Extensive Multiple 2D-/3D-QSAR Modeling, Molecular Docking
and Pharmacophoric Approaches for Piperazinylquinoline Derivatives
as Respiratory Syncytial Virus Fusion Inhibitors
Authors: Purohit Vipul P. , Thorat Bapu R. , Mali Suraj N. , Wagh Rahul R. , Yamgar Ramesh S. 
Published: November 2022

Background:
The human respiratory syncytial virus (RSV) is responsible for
causing upper and lower respiratory tract infections in young children. RSV Fusion (F)
protein is a surface glycoprotein that facilitates virus entry into host cells. Thus, newer
designing of RSV Fusion (F) protein inhibitors is required on an urgent basis.

Methods:
In the present study, we have developed statistically robust.
Quantitative structure-activity relationship (QSAR) models for the effective designing
of newer analogues of piperazinylquinoline derivatives (H1-H12).

Results:
Our developed models were retained with high statistical parameters (R2 > 0.6
and Q2 > 0.5). Our developed pharmacophore, model (AADHRR_2) (indicating that two
hydrogen bond acceptors, one hydrogen bond donor, one hydrophobic group, and two
aromatic rings) is crucial for retaining the activities of piperazinylquinoline derivatives
against RSV. Moreover, docking analysis of 12 new analogues on RSV pre-F in complex
with 5C4 Fab (PDB ID: 5W23) and post-F trimeric protein (PDB ID: 3RRR) suggested
higher affinities of these molecules against studied targets with good docking
scores.

Conclusion:
Thus, one can implement developed QSAR models, docking analogy and
Pharmacophore models for identifications of potent leads for designed molecules as
RSV Fusion (F) protein inhibitors.
Investigating the Effects of Hyperbaric Oxygen Treatment in Necrotizing Soft Tissue Infection With Transcriptomics and Machine Learning (the HBOmic Study): Protocol for a Prospective Cohort Study With Data Validation
Authors: Vinkel Julie , Rib Leonor , Buil Alfonso , Hedetoft Morten , Hyldegaard Ole 
Published: November 2022

Background
Necrotizing soft tissue infections (NSTIs) are complex multifactorial diseases characterized by rapid bacterial proliferation and progressive tissue death. Treatment is multidisciplinary, including surgery, broad-spectrum antibiotics, and intensive care; adjunctive treatment with hyperbaric oxygen (HBO2) may also be applied. Recent advances in molecular technology and biological computation have given rise to new approaches to infectious diseases based on identifying target groups defined by activated pathophysiological mechanisms.

Objective
We aim to capture NSTI disease signatures and mechanisms and responses to treatment in patients that receive the highest standard of care; therefore, we set out to investigate genome-wide transcriptional responses to HBO2 treatment during NSTI in the host and bacteria.

Methods
The Effects of Hyperbaric Oxygen Treatment Studied with Omics (HBOmic) study is a prospective cohort study including 95 patients admitted for NSTI at the intensive care unit of Copenhagen University Hospital (Rigshospitalet), Denmark, between January 2013 and June 2017. All participants were treated according to a local protocol for management of NSTI, and biological samples were obtained and stored according to a standard operational procedure. In the proposed study, we will generate genome-wide expression profiles of whole-blood samples and samples of infected tissue taken before and after HBO2 treatment administered during the initial acute phase of infection, and we will analyze the profiles with unsupervised hierarchical clustering and machine learning. Differential gene expression will be compared in samples taken before and after HBO2 treatment (N=85), and integration of profiles from blood and tissue samples will be performed. Furthermore, findings will be compared to NSTI patients who did not receive HBO2 treatment (N=10). Transcriptomic data will be integrated with clinical data to investigate associations and predictors.

Results
The first participant was enrolled on July 27, 2021, and data analysis is expected to begin during autumn 2022, with publication of results immediately thereafter.

Conclusions
The HBOmic study will provide new insights into personalized patient management in NSTIs.

Trial Registration
ClinicalTrials.gov NCT01790698; https://clinicaltrials.gov/ct2/show/NCT01790698

International Registered Report Identifier (IRRID)
DERR1-10.2196/39252
Jumlah Bintil Fase Vegetatif Penentu Mutu dan Hasil Kacang Hijau (Vigna radiata L.) di Lahan Sawah Bekas Padi
Authors: Sari Triana , Taryono Taryono 
Published: November 2022

Mungbean is one of leguminosae, that has profitable prospect therefore it has been cultivated by Indonesian society. Mungbean showed early maturity, easy management during cultivation and can produce more biomass, about 11.00-12.00 t/ ha. Wwhen the crop residue is left in field, it benefits of increasing the nutrients and improving soil fertility. Such reason makes mungbean becomes more profitable than soybean and peanut. The mungbean genetic material is significant to develop superior mungbean and support sustainable agriculture. This research was conducted to study the presence of rhizobium after continues rice grwon fields, to determine the bean accession responsive to Rhizobium sp., and to determine the impact of Rhizobium sp. on the mungbean yields components. This research was conducted at Agrotechnology Innovation Centre of Universitas Gadjah Mada (PIAT UGM) Kalitirto, Berbah, Sleman, Yogyakarta in splitted completely randomized design (CRD) with two factors. The main factor is inoculation treatment and the sub-factor is 18 mung beans accessions. Observations included rhizobium infection, nodule components, fresh weight of plant, dry weight of plant and yield components. The data obtained was further analyzed using analysis variance of completely randomized design, a further test of Scott Knott, and correlation analysis. All accessions can be infected by rhizobium and there was an increase in number of nodules and the effective number of nodules in each observation time with the result that inoculation treatment was superior to the one without inoculation. Number of nodules at time of observations have positive corellation with yield component, increased number of nodules followed increased variable of yield component.
Evaluación de la calidad en champú comercial no medicado para perros en la Ciudad de México
Authors: Peña-Corona Sheila Irais , Juárez-Rodríguez Ivan , Vargas-Estrada Dinorah , Arvizu Tovar Laura Olivia , Amador-González Enrique , Soberanis Ramos Orbelín 
Published: November 2022

El objetivo del trabajo fue realizar un análisis de descriptivo de la calidad del champú para uso en perros que se comercializa en la Ciudad de México. Hasta la fecha, se carece de información al respecto, lo cual es importante para facilitar la selección y recomendación de estos productos por profesionistas de la veterinaria. Se estudiaron productos de 20 marcas comerciales, a los cuales se les realizaron pruebas fisicoquímicas, sensoriales y de desempeño, además de evaluar el contenido de sus etiquetas. El pH del champú varió entre 5.6 y 8.4; la viscosidad, entre 1 131 y 3 102 m P a - s; la densidad relativa, entre 1.002 y 1.099 g/mL y el índice de espuma entre 2.9 y 4.0 min. El 95 % de los champús formaron espuma cerrada, mientras que entre el 10 y el 35 % de las marcas presentaron deficiencias en el etiquetado. En general, las propiedades físico-químicas y sensoriales de las marcas de champú bajo estudio se encuentran dentro de los límites aceptables para la línea de uso en humanos. No obstante, la falta de consistencia en el etiquetado sugiere que es necesario mejorar la supervisión de la normatividad aplicable para proteger la salud animal y pública.
Determining the Occupational Health and Safety of Workers in The Food Manufacturing Sector of Pakistan
Authors: Atiq Nazia , Akhlaq Ather 
Published: November 2022

Background: For organizations, conducting work in a safe environment has become mandatory under the provisions and guidelines provided by international and local laws. Occupational health and safety (OHS) standards have become a requisite in almost every industry these days; however, many organizations in developing countries are negligent at adhering to the safety measures, and there is also an absence of proper monitoring.
Objective: Our objective was to determine the occupational health and safety standards that are prevailing in the food manufacturing sector of Pakistan. For this, we approached several food manufacturing companies and conducted interviews with quality assurance managers and health and safety executives to evaluate and analyze the workplace conditions to understand their OHS practices.
Methods: We conducted 7 interviews with quality assurance managers in the food manufacturing and services companies of Pakistan. The interview guide was used for eliciting responses and a coding method was used to arrive at the themes of the data gathered.
Results: The interviews conducted with quality assurance managers and those working to ensure that safety measures are practiced in their company, showed that the export-oriented food manufacturing companies in Pakistan are following OHS standards, as it has become a necessity, with numerous
benefits such as ensuring worker safety, maintaining company reputation. However, the extent to which these measures are implemented and strictly followed varies, as there are certain issues that arise when companies try to follow and implement OHS practices The problems vary from company to company however, most of them relate to worker adaptability, costs, and training needs. OHS situation in local firms is concerning. Most of them do not have HSE officers, not the concept of toolbox talk, no preventive and safety measures. These poor practices make the situation unsafe, which lead to fatalities
Conclusion:
By establishing a national framework for policies and legislations as per the conventions of ILO for a better workplace environment along with proper law enforcement improvement in occupational health and safety domain can be achieved.
Evaluasi Program Desa Tangguh Bencana dalam Perspektif Flood Risk Management
Authors: Danar Oscar Radyan , Anggriawan Tommy , Prameisa Dellarizki 
Published: November 2022

Pacitan district is one of the five districts included in the highest disaster risk region in East Java. One of the area with a big threat of destructive flood disaster is Sirnoboyo Village, which is located between Grindulu and Jelok River. An attempt to improve community preparedness in the midst of flood hazard are carried out through Village Disaster Resilience Program. Village disaster resilience program is a form of flood risk management (FRM) as a community-based disaster risk reduction by building up self-sufficiency and adaptation. FRM is a theoritical analytic-based that is used in conjuction with Context, Input, Process, and Product (CIPP) evaluation model. The qualitative-descriptive approach was chosen to describe chronologically the evaluation of village disaster resilience program, which encounters several obstacles such as lack of active community and youth participation and under-capacity of the volunteer team. This study offers a reconstruction of village disaster resilience program execution in accordance with the FRM framework to effectively maximize community readyness over the threat of flood hazard that stakeout throughout a year.
Program Pemberdayaan Usaha Mikro di Kelurahan Pasar Ambacang Kota Padang
Authors: Vadyla Nadya , Malau Hasbullah 
Published: November 2022

The purpose of this study is to analyze the factors constraining the Online Single Submission System (OSS) in the UMKM program in Pasar Ambacang Village, Padang City. The background of this study explains that UMKM is still not developing because there is no review carried out by the Office of the development of UMKM groups in Pasar Ambacang Village, Padang City. This research was conducted using a descriptive qualitative approach. Test the validity of the data with triangulation techniques. Collecting data through interviews, documentation. The data analysis technique that the researcher uses is the manual data analysis procedure (MDAP). The results of the study explain that there are several obstacles experienced by the community related to this OSS policy, namely the community's understanding of technology is still low and there is still a lack of socialization of the OSS system from the kelurahan so that it is necessary to increase socialization by the Pasar Ambacang Village. thus this OSS system can be used by easy for the people.
The Role of Diet in the Treatment of Chronic Diseases Case Study
Authors: Aurora Craciun , Cecilia Adumitresei , Adina Honcea 
Published: November 2022

AbstractIn the context of chronic diseases, drug treatment is often long-term, perhaps even lifelong. Although in therapeutic terms the hygienic-dietary regime is very important, the importance of diet is still neglected by the patient. Diet and lifestyle have a special role in maintaining health, longevity and treating various ailments. It is known that a large part of adults between the ages of 20-70 suffer from obesity and that according to the data provided by the WHO, the main causes of mortality in the world are related to unhealthy eating, 14 million deaths are caused annually by an unbalanced diet globally. In this context, the population of Romania mainly has an unhealthy diet based on an increased intake of saturated fats, carbohydrates and protein and an insufficient intake of vitamins, minerals and enzymes from fruits, vegetables and seeds.The 62-year-old CV patient from Constanţa presented herself at the nutrition clinic for being overweight, having several chronic conditions. Through an appropriate and customized diet low in sodium, hypoprotein and hypocaloric, he managed to return to normal weight and significantly alleviates all the chronic conditions initially presented, together with the return of biochemical analysis results to normal levels, values maintained over time.