bluuebunny/crossref_metadata_2025_split huggingface dataset:
Economic Outcomes and Incidence of Postsurgical Hypotension With Liposomal Bupivacaine vs Epidural Analgesia in Abdominal Surgeries
Authors: Holtz Margaret , Liao Nick , Lin Jennifer H. , Asche Carl V. 
Published: September 2022

Background: Epidural analgesia can be associated with high costs and postsurgical risks such as hypotension, despite its widespread use and value in providing opioid-sparing pain management. We tested the hypothesis that liposomal bupivacaine (LB) might be a reliable alternative to epidural analgesia in this real-world study. Objectives: To compare economic outcomes and hypotension incidence associated with use of LB and epidural analgesia for abdominal surgery. Methods: This retrospective analysis identified records of adults who underwent abdominal surgeries between January 2016 and September 2019 with either LB administration or traditional epidural analgesia using the Premier Healthcare Database. Economic outcomes included length of stay, hospital costs, rates of discharge to home, and 30-day hospital readmissions. Secondary outcomes included incidence of postsurgical hypotension and vasopressor use. Subgroup analyses were stratified by surgical procedure (colorectal, abdominal) and approach (endoscopic, open). A generalized linear model adjusted for patient and hospital characteristics was used for all comparisons. Results: A total of 5799 surgical records (LB, n=4820; epidural analgesia, n=979) were included. Compared with cases where LB was administered, cases of epidural analgesia use were associated with a 1.6-day increase in length of stay (adjusted rate ratio [95% confidence interval (CI), 1.2 [1.2-1.3]]; P<.0001) and $6304 greater hospital costs (adjusted rate ratio [95% CI], 1.2 [1.2-1.3]]; P<.0001). Cost differences were largely driven by room-and-board fees. Epidural analgesia was associated with reduced rates of discharge to home (P<.0001) and increased 30-day readmission rates (P=.0073) compared with LB. Epidural analgesia was also associated with increased rates of postsurgical hypotension (30% vs 11%; adjusted odds ratio [95% CI], 2.8 [2.3-3.4]; P<.0001) and vasopressor use (22% vs 7%; adjusted odds ratio [95% CI], 3.1 [2.5-4.0]; P<.0001) compared with LB. Subgroup analyses by surgical procedure and approach were generally consistent with overall comparisons. Discussion: Our results are consistent with previous studies that demonstrated epidural analgesia can be associated with higher utilization of healthcare resources and complications compared with LB. Conclusions: Compared with epidural analgesia, LB was associated with economic benefits and reduced incidence of postsurgical hypotension and vasopressor use.
Comparison of the Success Rate of Radial Arterial Cannulation with Palpation Techniques and Ultrasound Guidance in Patients Undergoing Major Surgery with General Anesthesia
Authors: Zaini Afriza Rizqi , Fredi Heru Irwanto  , Mayang Indah Lestari  , Erial Bahar  , SNA Ratna Sari Devi  
Published: September 2022

Background: Ultrasound-guided arterial cannulation has the potential to increase the total success rate and first attempt and reduce complications compared to conventional landmark palpation methods. This study aims to compare the success rate of radial artery cannula with palpation techniques and ultrasound guidance in patients undergoing major surgery under general anesthesia.
Methods: This study is a randomized controlled trial singly. The inclusion criteria for this study were patients who underwent both emergency and elective surgery under general anesthesia, aged >18 years, with ASA I and II physical status. The study sample (60 people) was randomized by computer and divided into two groups (ultrasound guidance and palpation technique). The study will assess the success of the first insertion of the radial artery cannula in both groups. Data analysis was performed with SPSS 25 univariate and bivariate.
Results: There is a significant relationship with the success of the first attempt at an ultrasound-guided cannula trial with a p-value of 0.045 with an odds ratio of 3.33 with a 95% confidence interval (0.998 – 11.139).
Conclusion: Ultrasound-guided arterial cannulation has a better success rate and fewer complications than conventional palpation techniques.
PELAKSANAAN EKSEKUSI TERHADAP OBJEK JAMINAN FIDUSIA UNTUK PEMENUHAN KEWAJIBAN DEBITUR DALAM PERJANJIAN KREDIT DI PT. BPR. KANAYA
Authors: Setiabudi Komang Agus , Lemes I Nyoman 
Published: September 2022

Pelaksanaan eksekusi obyek jaminan fidusia, ternyata sering menimbulkan masalah. Masalah dapat datang dari pihak kreditur, atau dari debitur berupa upaya menghalang-halangi pelaksanaan eksekusi. Penelitian ini meneliti pelaksanaan eksekusi terhadap objek jaminan fidusia untuk pemenuhan kewajiban debitur dalam perjanjian kredit pada PT. BPR. Kanaya dan kendala-kendala yang dihadapi dalam pelaksanaan eksekusi tersebut. Penelitian ini merupakan penelitian hukum empiris, bersifat deskriptif. Pengumpulan data dilakukan dengan studi dokumen dan wawancara. Data yang terkumpul dianalisis secara kualitatif. Eksekusi terhadap objek jaminan fidusia pada PT. BPR. Kanaya dilaksanakan jika wanprestasi disepakati oleh debitur. Jika debitur menyepakati wanprestasi yang terjadi dan menyerahkan objek fidusia secara suka rela maka dapat dijual melalui pelelangan umum atau di bawah tangan. Jika tidak harus diajukan permohonan kepada pengadilan. Kendala-kendala yang dihadapi dalam pelaksanaan eksekusi terhadap objek jaminan fidusia pada PT. BPR. Kanaya, antara lain adanya keharusan untuk mengajukan kepada Pengadilan Negeri apabila debitur tidak sepakat mengenai adanya wanprestasi dan tidak bersedia menyerahkan barang yang dibebani fidusia secara sukarela, ada kecenderungan debitur tidak bersedia membuat kesepakatan penjualan barang secara langsung, adanya potensi gangguan keamanan dalam eksekusi terhadap barang tersebut, dan adanya gangguan dalam pendaftaran fidusia secara elektronik.
Fire and explosion hazard of refrigerant R-365mfc and fireproof mixtures based on it
Authors: Елтышев Илья Павлович 
Published: September 2022

Рассмотрена проблема пожарной опасности хладагента R-365mfc, являющегося парниковым газом. Определен класс его опасности как хладоносителя. Предложен способ снижения класса опасности путем создания негорючих смесевых композиций R-365mfc с ингибиторами горения с коротким временем жизни в атмосфере. Показана возможность сокращения в смесевой композиции хладагента доли парникового компонента на 45,8 % (масс.).
In connection with the adoption of a number of international environmental agreements the production of refrigerants which are greenhouse gases should be significantly reduced. This will lead to a shortage of refrigerants used in refrigeration and climate technology, as well as in other industries. A possible way to solve the problem of using greenhouse gases is to create mixed compositions with reduced content of the greenhouse component. At the same time the hazard class of the R-365mfc refrigerant is unknown. In this paper this refrigerant will be investigated and its hazard class will be determined. To solve the problem of using greenhouse gases the paper proposes the creation of non-combustible compositions with a flammable refrigerant R-365mfc with combustion inhibitor CF and CFO which are short-lived substances in the atmosphere. There were carried out the studies aimed at determining the hazard class and creating non-combustible compositions on the experimental installation “Variant” at atmospheric pressure. It is expected that when added to R-365mfc a heavy inhibitor with a high heat capacity will cause a strong inhibitory effect on the combustion process, it will also be important if this inhibitor is able to chemically inhibit the combustion process through interaction with the active sites responsible for its occurrence. It was ascertained that R-365mfc belongs to the A2L hazard class, and the non-combustible mixed composition based on R-365mfc is 54.2 % wt. R-365mfc - 42.8 % wt. CF(a). The possibility of reducing the proportion of the greenhouse component in the mixed composition of the refrigerant by 45.8 % by weight is shown. The efficiency of combustion inhibition is determined by the characteristics of the thermal degradation of inhibitors in the flame.
Comparison of Hematological and Inflammatory Markers to Predict Outcome in Covid-19 in 1st and 4th Wave
Authors: Khan Khalid , Khan Hamzullah , Khan Shahtaj , Fawad Khan Mohammad , Ali Mohammad , Usman Mohammad 
Published: September 2022

OBJECTIVES:
To compare the values of the hematological and inflammatory markers in 1st and 4th waves to predict the outcome of COVID-19 in a hospital-based study.
METHODOLOGY:
This comparative study was conducted in the Department of Hematology, Hayatabad Medical Complex Peshawar, from April 2020 to 20 August 2021. Tests of significance (Independent t-test/Mann Whitney U test) and Chi-square test were used. Relevant information was recorded on a pre-designed proforma prepared following the study's objectives.
RESULTS:
A total of 178 patients, 71 from (the 1st wave) and 107 from (the 4th wave) with known outcomes, were studied. A statistically significant difference exists between the groups (1st vs 4th wave) regarding hematological markers; neutrophil to lymphocyte ratio (NLR) (p=0.02), Absolute Neutrophilic count (ANC) (p=0.01) and platelet count (p=0.001). Similarly, significantly higher inflammatory markers values were recorded in the 1st wave compared with the 4th wave regarding inflammatory markers; CRP (p=0.002) and D-dimer (p=0.001). During the 1st wave, Total Leukocyte Count (TLC), ANC and d-dimer were the leading prognostic indicators to predict mortality/worst outcome in COVID-19 with an Area Under Curve (AUC) of 0.74, 0.70 and 0.7 on receiver operating characteristics (ROC) respectively. In 4th, the Area under the curve (AUC) of d-dimer was 0.84 to predict mortality.
CONCLUSION:
TLC, ANC, NLR, and low platelet count were the worst hematological markers in COVID-19 in the first wave, while d-dimer and CRP were the primary prognostic inflammatory markers. Unlikely in the 4th wave, the prognostic values of hematological markers were merely significant. The d-dimer values in both the waves proved to be reliable for predicting the severity and mortality of COVID-19.
Tension histoire/mémoire dans la valorisation du patrimoine scientifique et technique : une perspective critique
Authors: Lamy Jérôme 
Published: September 2022

L’article interroge la position des historiens des sciences intervenant dans les démarches patrimoniales. Les opérations historique et mémorielle sont substantiellement antinomiques : la première vise à comprendre le passé, la seconde à unifier une communauté. Le patrimoine, qui est une forme concrètement déclinée de pratique mémorielle, mobilise parfois les historiens. Les enjeux politiques et économiques sous-jacents obligent à une mise à distance critique peu aisée. Dans le domaine de l’histoire des sciences et des techniques, les célébrations institutionnelles, les expositions et les musées sont autant d’espaces dans lesquels histoire et mémoire s’affrontent ou se concurrencent. Le souci du public, l’emprise des scientifiques, le travail des groupes d’amateurs, les intérêts politiques et les mémoires des lignées scientifiques limitent ou rendent malaisée la pratique historienne. L’article plaide, in fine, pour un processus critique visant à légitimer l’autonomie et les spécificités de l’histoire des sciences lorsqu’elle est mobilisée dans les processus patrimoniaux.
L’instrument technique à la rencontre du public
Authors: Soulu Frédéric 
Published: September 2022

Le château observatoire d’Abbadia, propriété de l’Académie des sciences, fut un laboratoire de géophysique et d’astronomie pendant 150 ans. Ouvert aujourd’hui au public, ce lieu de mémoire expose une collection unique d’instruments scientifiques. Une réflexion muséographique est en cours autour de ce patrimoine et de son usage avec le public. Les enjeux sont nombreux mais l’objectif principal est d’initier le public à un regard critique et constructif sur la science. En proposant la manipulation d’un objet scientifique patrimonial, un contact nouveau avec le public peut être créé. L’instrument est utilisé un témoin signifiant de l’activité scientifique. Une carte de son « biotope » est proposée, sur laquelle se fonde le discours au public. Enfin, plusieurs expériences » jalons » sont analysées afin d’ouvrir une voie originale.
Management of Densely Calcified Coronary Lesions using OPN–NC Balloon and Shockwave Intravascular Lithotripsy Procedure
Authors: Bagur Manjunath Venkataramaiah 
Published: September 2022

Background:
Calcified coronary lesions are challenging to the interventional cardiologists to manage. Debulking the calcified lesions with Rotablation is a well known strategy. Shockwave intravascular lithotripsy (IVL) is the newer novel therapeutic procedure found to be very effective in PCI of calcified lesions.

Aims and Objectives:
To assess the clinical utility of Shockwave IVL in densly calcified coronary lesions.

Materials and Methods:
Four patients underwent PCI with Shockwave IVL for densly calcified lesions between Febraury and March of 2020 and were followed up clinically in our centre.

Results:
All patients are doing well clinically without any coronary events.

Conclusion:
Shockwave IVL is safe and accepted modality of debulking the densly calcified coronary lesions and prepare the bed for optimal stent deployment.
Susceptibility status of Anopheles gambiae s.l. to insecticides used for malaria control in Kinshasa, Democratic Republic of the Congo
Authors: Zanga Josué , Metelo Emery , Mbanzulu Kennedy , Irish Seth , Mulenda Basimike , Wumba Roger Di-Mosi , Masiangi Paul 
Published: September 2022

Contexte et objectif. Malgré plusieurs années de lutte, le paludisme demeure toujours la première cause de mortalité infantile sous les tropiques. Actuellement, la stratégie de contrôle vise des actions simultanées contre l’agent causal et le vecteur du paludisme. L’objectif de la présente étude était de décrire la distribution de la sensibilité d'Anopheles gambiae sl aux insecticides à travers la ville de Kinshasa. Méthodes. Des larves d'anophèles ont été collectées, à travers sept sites de Kinshasa, pendant la période allant de septembre 2017 à mai 2018. Des bioessais standard de l'OMS ont été utilisés pour mesurer la sensibilité d'Anopheles gambiae s.l. aux insecticides. La distribution des espèces et le profil de résistance ont été évalués en recourant aux tests diagnostiques moléculaires. Résultats. Deux espèces du complexe gambiae ont été identifiées : An. gambiae (98,3 %) et An. coluzzii (1,7 %). Une variabilité du statut de résistance à la deltaméthrine par site a été observée. Cependant, une restauration de la sensibilité a été notée après une pré-exposition au butoxyde de pipéronyle (PBO) dans tous les sites présentant une résistance à la deltaméthrine. Conclusion. La présente étude a démontré qu’An. gambiae s.l. était résistant à la perméthrine dans tous les sites retenus. Cependant, la résistance à la deltaméthrine était variable. Le profil de résistance indique que les moustiquaires deltaméthrine+PBO devraient être envisagées pour la lutte anti vectorielle.
Context and objective. Despite many years of control, malaria remains the leading cause of child mortality in the tropics. Currently, the control strategy aims at simultaneous actions against the causal agent and the vector of malaria. This study aimed to describe the distribution of the susceptibility of Anopheles gambiae sl to insecticides across the city of Kinshasa. Methods. Anopheles larvae were collected from seven sites in Kinshasa during the period from September 2017 to May 2018. Standard WHO bioassays were used to determine the sensitivity of Anopheles gambiae s.l. to insecticides. The species distribution and the resistance profile were evaluated by polymerase chain reaction. Results. Two species of the gambiae complex were identified: An. gambiae (98.3 %) and An. coluzzii (1.7 %). Variability of deltamethrin resistance status by site was observed; however, a restoration of susceptibility was noted after pre-exposure to piperonyl butoxide (PBO) in all sites with deltamethrin resistance. Conclusion. The present study showed that An. gambiae s.l. was resistant to permethrin in all the selected sites. However, resistance to deltamethrin was variable. The resistance profile indicates that deltamethrin+PBO nets should be considered for vector control.
Kajian Perbandingan Analisis Finansial Perkebunan Kelapa Sawit Rakyat dan Swasta
Authors: Artana I Kadek Pandi Beri , Trisna Anak Agung Inten , Arisena Gede Mekse Korri 
Published: September 2022

Kajian ini bertujuan untuk membandingkan analisis kelayakan finansial dan manajemen usaha pada dua jenis kepemilikan perkebunan kelapa sawit di Indonesia. Kepemilikan perkebunan kelapa sawit tersebut adalah perkebunan kelapa sawit rakyat dan swasta di ada di wilayah Indonesia. Metode yang digunakan adalah studi literatur dengan sumber pustaka dicari dari sistem aplikasi Harzing yang meliputi mengenai NPV, IRR, B/C Ratio, dsb pada perkebunan kelapa sawit swasta dan rakyat. Hasil dari kajian ini didapat pada aspek finansial perkebuanan kelapa sawit swasta terdapat biaya reinvestasi yang di bebankan pada biaya pengeluaran untuk usaha perkebunan kelapa sawit swasta, sedangkan pada rakyat tidak ada ditemukannya biaya reinvestasi yang dibebankan pada pengeluarannya. Rata-rata perkebunan swasta menganalisis switching value untuk menyiapkan strategi menghadapi tantangan kedepan seperti penurunan produksi ataupun kenaikan biaya produksi. Berdasarkan hal tersebut, diharapkan hasil kajian ini dapat menjadi acuan kepada pengembang maupun pemerintah maupun stakeholder terkait.
La integración europea en la política de I+D: el espacio europeo de investigación, la resiliencia de un proyecto en constante evolución
Authors: ARIZAGA BATIZ ANA 
Published: September 2022

El proyecto político de creación de un Espacio Europeo de Investigación(EEI), concebido como un mercado interior del conocimiento en el quese materialice la libre circulación de investigadores, conocimiento y tecnologías,viene históricamente inspirando el despliegue de la política europea de investigacióny desarrollo tecnológico. De hecho, constituye su visión más ambiciosa,orientada a una verdadera integración de la investigación europea. Se trata, sinembargo, de un objetivo muy ambicioso que ha progresado de forma vacilante yaún queda recorrido para alcanzar su compleción y óptimo funcionamiento. El EEI,pese a todo, sigue constituyendo el marco teórico y político que impulsa esa integracióneuropea en el sector de la I+D, gracias a su capacidad para reinventarsea la luz de las sucesivas agendas políticas europeas y, en esta década 2021-2030,mantiene su protagonismo como herramienta al servicio de los actuales retos dela Unión.
Europako Ikerketa Esparrua (EEI) sortzeko proiektu politikoa,ikerlarien, ezagutzaren eta teknologien zirkulazioa askea gauzatuko den esparruaeta ezagutzaren barne-merkatu izateko pentsatua, ikerketa eta garapen teknologikorakoEuropako politika hedatzeko inspirazio-iturri izan da historikoki. Izan ere,asmo handiko ikuspegia da, Europako ikerketa benetan integratzera bideratua.Oso asmo handiko helburua izanik ere, modu gorabeheratsuan egin du aurreraeta oraindik ere bide luzea du osatu eta egoki funtzionatzen hasteko. Hala eta guztizere, EEIk jarraitzen du izaten I+Gren sektorean europar integrazio hori bultzatzenduen esparru teoriko eta politikoa, une bakoitzeko Europako agenda politikoraegokitzeko izan duen gaitasunari esker. 2021-2030 hamarkada honetan protagonistaizaten jarraitzen du Batasunaren egungo erronken zerbitzurako tresna gisa.
The political project of creating a European Research Area (ERA),conceived as an internal knowledge market in which the free circulation ofresearchers, knowledge and technologies materializes, has historically inspiredthe deployment of European research and technological development policy.In fact, it constitutes its most ambitious vision, aimed at a true integration ofEuropean research. It is, however, a very ambitious objective that has progressedhesitantly and there is still a long way to go to achieve its completion and optimalfunctioning. The ERA, despite everything, continues to constitute the theoreticaland political framework that drives this European integration in the R&D sector,thanks to its ability to reinvent itself in the light of successive European politicalagendas and, in this decade 2021-2030, maintains its leading role as a tool at theservice of the Union¿s current challenges.
Competence and Worker’s Attitude in Health Ministries in South-South, Nigeria
Authors: Idoniboyeobu Anyanaba Dikio , Gabriel J M O , Asawo S P 
Published: September 2022

Purpose: This study examined the relationship between competence and worker’s attitude in health ministries in South-South, Nigeria.
Methodology: The study adopted a cross-sectional survey research design. Primary data was generated through a 4-point Likert scaled questionnaire. The population of the study was two thousand one hundred and eighty-one (2181) employees. A sample size of three hundred and thirty-eight (338) employees was drawn from the population using the Taro Yamane sample size determination formula. The study adopted the simple random sampling technique. The reliability of the instrument was ascertained using the Cronbach Alpha coefficient with all the items scoring above 0.70. The hypotheses were tested using Spearman Rank Order Correlation Coefficient with the aid of Statistical Packages for Social Sciences.
Findings: The findings revealed that competence had a significant positive relationship with affective commitment, affective satisfaction and workers engagement. Therefore, the study concludes that the level of competence thus has a direct bearing with worker’s attitude. Inability of employees to perform maximally due to lack of competence will result in higher dissatisfaction.
Recommendation: Thus the researchers recommend that the management of the Health Ministries should embark on proper training and development of the workers to enhance their knowhow in the work as such will help boost their positive work attitude.