bluuebunny/crossref_metadata_2025_split huggingface dataset:
User-friendly street- a study on users' perception ranking on physical attributes of pedestrian environment of Dhaka city
Authors: Israt Abontika Sara , Hassan Ahmad Sanusi 
Published: February 2022

PurposeThe purpose of this research is to examine the current physical qualities and activities of pedestrian environment from the perspective of the users' needs and perceptions for making user-friendly streets in Dhaka city.Design/methodology/approachCase study research approach was adapted with a mixed method approach in data collection and analysis to gather information about the interrelationship concerning the variables. The questionnaire survey and direct observation was conducted with the users of the streets to get the actual scenes of the study areas. For the findings, multiple sources of evidence were triangulated and used to analyze which were derived from the convergence of the data.FindingsThe findings of this study show that the needs for the factors which make people to use the street are similar with the previous theories derived by different scholars. The results establish that making of user-friendly street from the users' perspective has a significant relationship with the attributes of public spaces in the context of Dhaka. Correlation among the attributes of public spaces concerning sociability, uses and activities, access and linkage and safety, comfort and image showed the issues affecting the pedestrian environment toward a crucial condition in Dhaka city.Research limitations/implicationsTime allocation, inadequacy of secondary data sources and earlier research on this topic in the context of Dhaka city, were the primary limitations to let an in-depth and full exploration of the research.Originality/valueThe study provided a detailed representation of Dhaka's users' perception of the pedestrian environment. This study suggests a new perspective of bettering pedestrian experience in the city center.
Place attachment, migratory behaviour and its impact on economic activity: a study with special reference to Eastern India
Authors: Adhikari Subrato , Mandal Anirban , Kujur Fedric , Guha Sriparna 
Published: February 2022

PurposeThe aim of this study is to define the aspects of place attachment and their effect on migratory behaviour. It also aims to identify the connection between migration decision-making and workforce supply at the source, as well as to track the impact of adequate employment supplies and the improvement on employment generation.Design/methodology/approachA primary study was conducted among the migrants who returned back during nationwide lockdown with the help of tested structured questionnaire. The variables identified through review of literature and pilot study are tested using a structural equation modelling model.FindingsThe result exhibited that all hypothesised relationships had a positive and significant connection. The overall results showed there is a significant and positive connection between place attachment and migratory behaviour, and both have a positive impact on economic activity.Originality/valueThis survey is conducted in the districts of West Bengal, India. There are several documents on the connection to the place attachment and the migratory behaviour. There are, however, no studies focusing on place attachment and its effect on economic activity on West Bengal, India, where migration is a serious problem. This is the first article that discusses three main concepts together such as place attachment, migratory behaviours and its influence on the economic activity of the districts of West Bengal, India.
Restoring public confidence through the delivery of improved community policing in Rackhamshire
Authors: O’Reilly Carina , Agnew-Pauley Winifred , Lundrigan Sam 
Published: February 2022

Purpose
Neighbourhood policing is central to supporting public confidence in England and Wales. However, the delivery of neighbourhood policing models is increasingly fragmented and under pressure from austerity measures and from changes to demand and priorities. This research aims to understand the current state of neighbourhood policing in the county of “Rackhamshire” and its ability to support public confidence.

Design/methodology/approach
The authors conducted six focus groups, three with officers who were part of Community Policing Teams (CPTs) and three with members of the community who were actively engaged with community policing and local concerns. These were supplemented by two interviews with senior officers (35 participants in total).

Findings
Austerity-driven changes to policing in Rackhamshire have damaged the capacities of CPTs and residents have begun to lose confidence in the ability of the police to respond to their fears. The authors argue that reforms intended to make policing more efficient and effective appear to have the opposite effect on community policing, by preventing it from working in a way that can support public confidence and that this could have longer-term consequences.

Originality/value
The effects of austerity on the mechanisms by which neighbourhood policing supports confidence have been relatively neglected. By exploring the state of these mechanisms in one English constabulary, this research has exposed serious weaknesses in the way that community policing is able to support public confidence and suggests practical operational responses. In light of these findings, this study argues for the urgent reinstatement of earlier models of neighbourhood policing.
Five strategic tech and talent trends for 2022 and beyond
Authors: Cooney Haynes , Marshall Anthony , Zaharchuk David 
Published: February 2022

Purpose
Over the past year, the IBM Institute for Business Value (IBV) surveyed and interviewed tens of thousands of executives, employees and consumers around the world to learn what high-performing organizations are doing differently, and where executives are making the biggest bets.

Design/methodology/approach
After thousands of interviews over several years the researchers identified five trends that executives can explore to help prepare for a future characterized by disruption and change.

Findings
Executives are learning how to redefine how humans and technology work together.

Practical/implications
Businesses need to reinvent their operations holistically to realize the full benefits of digital transformation.

Originality/value
A comprehensive record of strategic tech and talent trends the leaders can use to prepare for 2022 and beyond.
Interorganizational coworking: attenuating complexity, enhancing resilience and fostering open innovation and knowledge cocreation
Authors: Hysa Xhimi , Themeli Artemisa 
Published: February 2022

Purpose
This study aims to explore how interorganizational coworking spaces (CWS) affect complexity, resilience, open innovation and knowledge cocreation.

Design/methodology/approach
This is a qualitative study using the exploratory design. Data are gathered through semistructured interviews and naturalistic observation in six different CWS.

Findings
In line with previous studies, the findings show that being in a CWS with professionals of various backgrounds and contained levels of diversity make people prone to communication and knowledge sharing. Differently from previous research about knowledge creation in CWS, this study discovered that knowledge cocreation was only averagely affected. Complexity and resilience were the most influenced dimensions with scores higher than average, followed by open innovation and knowledge cocreation.

Research limitations/implications
Main limitations are related to the qualitative method itself which may not reach the data saturation and with the nonsynergistic analysis of all dimensions together. A further limitation arose because of the COVID-19 pandemic which contributed to downsizing the number of participants while restricting the options of the involved research instruments. The implications for research are related to a need for further studies using large-scale surveys to strengthen the reliability of research. Additionally, more research is needed to explore the multiple dimensions of open innovation, complexity and resilience in CWS.

Practical implications
For CWS providers, it is recommended to create thematic/clustered areas of collaboration based on specific professions. For early-stage businesses, freelancers and micro/entrepreneurial firms that do not wish to lease their own office, CWS provide an opportunity for value cocreation and open innovation.

Social implications
CWS, either physical or virtual, can be used as a retreat approach and a socialization platform, especially for those in need to recover from post-traumatic stress due to the imposed isolation caused by COVID-19 pandemic.

Originality/value
Given the unexplored phenomena of complexity and resilience in CWS, the major contribution of this research is related to the impact of interorganizational coworking upon complexity and resilience.
The dynamics of structure, social interaction and flow – the case of Rosenborg Ballklub
Authors: Steiro Trygve J. , Syvertsen Carsten M. , Saksvik Per Øystein , Vennatrø Ragnar Magnus 
Published: February 2022

Purpose
The purpose of this study is to look into the extraordinary performance of Rosenborg Ballklub (RBK) under coach Nils Arne Eggens’ leadership with several appearances in the Champions League, competing with more clubs with more resources.

Design/methodology/approach
In-depth interviews with the coach and key players. Also combining with document studies.

Findings
This study identified six key postulates that could be viewed as a minimal structure that was important for creating a picture of how Rosenborg’s attack play should be carried out. This study identifies a high commitment to the way of playing. Even if the way of playing was well known, the play was carried out with both a high pace and precision, making it hard for opponents to defend. The play pattern is closely linked to social interaction. Furthermore, the playing pattern was reproduced repeatedly, creating a platform for collective mastery.

Research limitations/implications
The current study provides a detailed insight into the development of performance within a football club using different approaches. However, creating a common picture of what should be performed.

Practical implications
The current study can provide insight to football clubs but also other teams identifying a common pattern based on certain values.

Social implications
The study of Rosenborg Ballklub demonstrates the combinations of individual characters and strength (signature strength) within a collective using a holistic and complementary approach. One should focus on the strength of the team.

Originality/value
Original in understanding the way RBK performed. It also demonstrates a unique insight in applying flow theory as a means of developing a football team.
Leaders' attitudes towards, and commitment to quality management of training within the military
Authors: Els Renier Christiaan , Meyer Helen H.W. 
Published: February 2022

PurposeThe successful implementation of quality management in organizations is dependent on people, particularly leaders. It seems as if leaders' affective states (attitudes and commitment) in the military were connected to their capability to inspire people and a group (corps training unit) to achieve a common goal. The research reported in this article was aimed at examining officers in corps training units' attitudes towards, and commitment to quality management in training in the South African Army.Design/methodology/approachFocus group interviews were conducted with a sample of 49 officers on various levels (senior, junior and warrant officers) at six South African Army corps training units.FindingsThe findings indicate that the attitudes of leaders played a significant role to ensure that quality management of training is conducted effectively. Participants experienced that leaders in the South African Army were mostly responsible for the negative attitudes of officers in corps training units. Inadequate leadership support and lack of trust contributed to a lack of transparency and poor communication that resulted in poor commitment among officers at corps training units. The investigation further revealed that a positive affective state (attitudes and commitment) of leaders is essential in ensuring effective quality management of training.Originality/valueThe potential usefulness of this research may provide insight into how leaders' affective state could be improved to ensure effective quality management. This research may also be of interest to other organizations that conduct in-house training.
Effects of immune checkpoint blockade on antigen‐specific CD8+ T cells for use in adoptive cellular therapy
Authors: Ogando‐Rivas Elizabeth , Castillo Paul , Jones Noah , Trivedi Vrunda , Drake Jeffrey , Dechkovskaia Anjelika , Candelario Kate M. , Yang Changlin , Mitchell Duane A. 
Published: February 2022

AbstractAdoptive T‐cell therapies have been successfully used as prophylaxis or treatment for immunocompromised patients at risk of viral infections or advanced cancers. Unfortunately, for some refractory cancers, they have failed. To overcome this, checkpoint inhibitors are used to rescue immune antitumor responses. We hypothesized that in vitro checkpoint blockade during T‐cell stimulation and expansion with messenger RNA (mRNA)–pulsed DCs may enhance the activity of antigen‐specific T cells and improve the efficacy of adoptive cellular therapy platforms. Human peripheral blood mononuclear cells were isolated from cytomegalovirus (CMV)‐seropositive donors to generate DCs. These were pulsed with CMV matrix phosphoprotein 65 (CMVpp65)‐mRNA to educate T cells in coculture for 15 days. Three checkpoint blockade conditions were evaluated (anti‐PD1, anti‐Tim3, and anti‐PD1 + Tim3). IL‐2 and antibodies blockades were added every 3 days. Immunophenotyping was performed on Day 0 and Day 15. Polyfunctional antigen‐specific responses were evaluated upon rechallenge with CMVpp65 peptides. CMVpp65‐activated CD8+ T cells upregulate Lag3 and Tim3 (P ≤ 0.0001). Tim3 antibody blockade alone or in combination led to a significant upregulation of Lag3 expression on CD8+ pp65Tetramer+ central memory, effector memory, and terminal effector memory cells re‐expressing RA (TEMRA) T cells. This latter T‐cell subset uniquely maintains double‐positive Tim3/Lag3 expression after checkpoint blockade. By contrast, PD1 blockade had minimal effects on Tim3 or Lag3 expression. In addition, IFN‐γ secretion was reduced in T cells treated with Tim3 blockade in a dose‐dependent manner (P = 0.004). In this study, we have identified a potential activating component of Tim3 and linkage between Tim3 and Lag3 signaling upon blocking the Tim3 axis during T‐cell–antigen‐presenting cell interactions that should be considered when targeting immune checkpoints for clinical use.
Relationship between pediatric intensive care unit length of stay and 24‐h unplanned readmission rate
Authors: Bhat Moodakare Ashwini , Soto‐Campos Gerardo , Scanlon Matthew C. 
Published: February 2022

AbstractObjectiveTo evaluate the relationship between pediatric intensive care unit (PICU) severity‐adjusted length of stay (LOS) and 24‐h unplanned readmission rate.Data SourceData were obtained from a 10‐year cohort from 2009 to 2018 from the Virtual Pediatric Systems (VPS, LLC) database.Study DesignIn this retrospective study, standardized LOS ratio was computed for each PICU as the ratio of the sum of actual LOS divided by the predicted LOS for each PICU using VPS predictive LOS model. Correlation between standardized LOS ratios and 24‐h unplanned readmission rates were computed using Pearson's correlation coefficient.Principal FindingsThere was practically no relationship between standardized LOS ratio and 24‐h readmission rate (R2 = 0.05).Data Collection/Extraction MethodsNot Applicable.ConclusionsSeverity‐adjusted LOS has no relationship with 24‐h unplanned readmission rate. These findings suggest that the relationship between PICU severity‐adjusted LOS and 24‐h unplanned readmission rate should not be used as a balancing quality measure.
Valorization of fish byproducts: Sources to end‐product applications of bioactive protein hydrolysate
Authors: Nirmal Nilesh Prakash , Santivarangkna Chalat , Rajput Mithun Singh , Benjakul Soottawat , Maqsood Sajid 
Published: February 2022

AbstractFish processing industries result in an ample number of protein‐rich byproducts, which have been used to produce protein hydrolysate (PH) for human consumption. Chemical, microbial, and enzymatic hydrolysis processes have been implemented for the production of fish PH (FPH) from diverse types of fish processing byproducts. FPH has been reported to possess bioactive active peptides known to exhibit various biological activities such as antioxidant, antimicrobial, angiotensin‐I converting enzyme inhibition, calcium‐binding ability, dipeptidyl peptidase‐IV inhibition, immunomodulation, and antiproliferative activity, which are discussed comprehensively in this review. Appropriate conditions for the hydrolysis process (e.g., type and concentration of enzymes, time, and temperature) play an important role in achieving the desired level of hydrolysis, thus affecting the functional and bioactive properties and stability of FPH. This review provides an in‐depth and comprehensive discussion on the sources, process parameters, purification as well as functional and bioactive properties of FPHs. The most recent research findings on the impact of production parameters, bitterness of peptide, storage, and food processing conditions on functional properties and stability of FPH were also reported. More importantly, the recent studies on biological activities of FPH and in vivo health benefits were discussed with the possible mechanism of action. Furthermore, FPH‐polyphenol conjugate, encapsulation, and digestive stability of FPH were discussed in terms of their potential to be utilized as a nutraceutical ingredient. Last but not the least, various industrial applications of FPH and the fate of FPH in terms of limitations, hurdles, future research directions, and challenges have been addressed.
Functional implications of bound phenolic compounds and phenolics–food interaction: A review
Authors: Rocchetti Gabriele , Gregorio Rosa Perez , Lorenzo Jose M. , Barba Francisco J. , Oliveira Paula García , Prieto Miguel A. , Simal‐Gandara Jesus , Mosele Juana I. , Motilva Maria‐Jose , Tomas Merve , Patrone Vania , Capanoglu Esra , Lucini Luigi 
Published: February 2022

AbstractSizeable scientific evidence indicates the health benefits related to phenolic compounds and dietary fiber. Various phenolic compounds‐rich foods or ingredients are also rich in dietary fiber, and these two health components may interrelate via noncovalent (reversible) and covalent (mostly irreversible) interactions. Notwithstanding, these interactions are responsible for the carrier effect ascribed to fiber toward the digestive system and can modulate the bioaccessibility of phenolics, thus shaping health‐promoting effects in vivo. On this basis, the present review focuses on the nature, occurrence, and implications of the interactions between phenolics and food components. Covalent and noncovalent interactions are presented, their occurrence discussed, and the effect of food processing introduced. Once reaching the large intestine, fiber‐bound phenolics undergo an intense transformation by the microbial community therein, encompassing reactions such as deglycosylation, dehydroxylation, α‐ and β‐oxidation, dehydrogenation, demethylation, decarboxylation, C‐ring fission, and cleavage to lower molecular weight phenolics. Comparatively less information is still available on the consequences on gut microbiota. So far, the very most of the information on the ability of bound phenolics to modulate gut microbiota relates to in vitro models and single strains in culture medium. Despite offering promising information, such models provide limited information about the effect on gut microbes, and future research is deemed in this field.
A midgut‐specific lytic polysaccharide monooxygenase of Locusta migratoria is indispensable for the deconstruction of the peritrophic matrix
Authors: Qu Ming‐Bo , Guo Xiao‐Xi , Kong Lin , Hou Ling‐Jie , Yang Qing 
Published: February 2022

AbstractLytic polysaccharide monooxygenases (LPMOs) are important enzymes that boost the hydrolysis of recalcitrant polysaccharides, such as chitin. They are found extensively in different insect species and are classified as auxiliary activities family 15 (AA15) LPMOs (LPMO15). Some of them were identified from the insect midgut and proven to act on chitin. However, knowledge about their physiological roles during insect growth and development remains limited. Here, we found that midgut‐specific LPMO15s are widely distributed in different insect orders, such as the orthopteran Locusta migratoria and the lepidopteran Bombyx mori. Using L. migratoria as a model insect, the function of midgut‐specific LmLPMO15‐3 during development was investigated. Double‐stranded RNA‐mediated downregulation of LmLPMO15‐3 expression at the 4th or 5th instar nymph stage severely decreased the survival rate and resulted in lethal phenotypes. Hematoxylin and eosin staining results indicated that the deficient individuals exhibited incompletely digested peritrophic matrix (PM), which suggested that LmLPMO15‐3 is essential for the deconstruction of the PM during molting. This study provides direct evidence of the physiological importance of a midgut‐specific LPMO15 during insect development. As L. migratoria is one of the most destructive agricultural pests, LmLPMO15‐3 is a potential target for pest management.
Comparative study of the effects of ultrasonic power on the structure and functional properties of gliadin in wheat and green wheat
Authors: Zhang Kangyi , Wen Qingyu , Li Tianqi , Wang Yufei , Zhang Yu , Luo Denglin 
Published: February 2022

AbstractThe impact of different ultrasonic power on the structure and functional properties of wheat gliadin (WG) and green wheat gliadin (GG) was investigated and compared. Ultrasound had no obvious effect on subunit composition and bands of WG and GG, and there were more small molecular weight bands in GG. The results of Fourier transform‐infrared spectroscopy, intrinsic fluorescence spectroscopy, and scanning electron microscopy analyses demonstrated that ultrasonic treatment had a significant effect on the structure of WG and GG, inducing the transformation from order structure to disorder structure. The dispersion and uniformity were better at 400 and 300 W, respectively. Under proper ultrasonic treatment, the particle size of WG and GG was significantly reduced, and the free sulfhydryl groups and surface hydrophobicity were significantly increased (p < 0.05). Furthermore, the functional properties of WG and GG such as solubility, emulsification properties, water holding and oil holding properties, thermal stability, and digestibility were enhanced. The better functional properties of WG and GG were obtained at 400 and 300 W, respectively. These results indicated that ultrasonic treatment with appropriate power was a valuable method for improving functional characteristics of WG and GG.Practical ApplicationUltrasonic treatment could cause structural changes of wheat gliadin (WG) and green wheat gliadin (GG), and their functional properties are improved under appropriate power. This study compares the effects of ultrasound on WG and GG, and the results will provide theoretical guidance for the development of GG in the food industry.