bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case report: Lingering post-concussive symptoms in a pediatric patient with presumed Ehlers-Danlos syndrome
Authors: Curry Tala Maris , Esfandiarei Mitra , Thomas Theresa Currier , Rastogi Reena Gogia 
Published: November 2022

BackgroundConnective tissue disorders such as Ehlers-Danlos Syndrome (EDS) can affect collagen and elastin content and structure, including weakening of tissues and vasculature, thus contributing to multiple systemic manifestations. Prior research has successfully focused on peripheral life-threatening manifestations resulting in increased life expectancy, yet clinical observations have warranted investigation of neurological vulnerability, where little is known. Compromised brain tissues and cerebrovasculature could leave these patients vulnerable to mild traumatic brain injury (TBI), with increased severity and duration of post-concussive symptoms and delayed recovery. Clinical reports in adults indicate that higher severity of symptoms after a mild TBI, such as a concussion, can unmask connective tissues disorders leading toward diagnosis. This clinical case report is an example of a pediatric patient with presumed Ehlers-Danlos syndrome who demonstrates increased vulnerability to mild TBI/concussion.PatientA pediatric female patient presents with unexplained lingering post-concussive symptoms, including trouble sleeping, nausea, frontal headaches, dizziness, visual changes, fatigue, and left-sided weakness more than 6 months post-mild concussion. Patient history of hypermobility, joint derangement, soft tissue mobility, and bruising suggests a potential diagnosis of Ehlers-Danlos syndrome, which may explain symptom severity and length of recovery.DiscussionThis case is the first documented instance of increased vulnerability to TBI in a pediatric patient with presumed Ehlers-Danlos syndrome. It highlights the need for awareness and prevention of injury in this vulnerable patient population, suggests more targeted therapeutic intervention for recovery, and demonstrates the need for preclinical research evaluating the influence of genetic mutations associated with connective tissue disorders on the central nervous system.
Relationship between children’s skills in school subject learning and athletic ability
Authors: Ito Syuro 
Published: November 2022

Background and purposeJapanese elementary school children are trained in arts and crafts, music, arithmetic, the Japanese language, life environment studies, physical education, and so on. Children must learn through doing as they develop physically, because the range of activities in their daily lives is still narrow. Subject learning is inseparable from daily life. Teachers should plan lessons with an awareness of the physicality of activities. Therefore, this study clarified the relationship between the ability for skillful and quick physical movement and subject learning among Japanese elementary school students.MethodsFor the second to fourth grades of elementary school, the measurement results and subject evaluation (skill) were compared at the individual level. Students were divided into a group with high grades in subject learning and one with middle and lower grades, and a t-test was conducted to observe if there was a significant difference in the records of two physical activities: repeated side jump and softball throw.Main findingsSignificant difference was found for repeated side jumps depending on whether the arts and crafts grades were high for all children in grades 2–4. Additionally, there was a significant difference in softball throwing records between the second and third graders, depending on whether the children’s performance in arts and crafts was high. Conversely, there was no significant difference between the second to fourth grade children’s musical scores and repeated side jump records. There was a negative correlation between sophomore and senior year music performances and the softball throwing record. Thus, the development of children’s dexterity is related to subject learning.ConclusionConsidering that elementary school teachers spend sufficient time with children on a daily basis teaching subjects such as physical education and music, it may be beneficial for them to be aware of dexterity’s importance across multiple subjects. Furthermore, it allows for an approach that engages children in physical activities from early childhood which can help in preparing them for learning a variety of subjects in school.
Association between the reactivity of local cerebral oxygen saturation after hypo-to-hypercapnic tests and delirium after abdominal surgery in older adults: A prospective study
Authors: Song Jie , Cheng Chen , Sheng Kui , Jiang Ling-Ling , Li Yun , Xia Xiao-Qiong , Hu Xian-Wen 
Published: November 2022

ObjectiveThis study aimed to investigate the correlation between changes in regional cerebral oxygen saturation (rSO2) and postoperative delirium in older adults undergoing major abdominal surgery.Materials and methodsThis prospective study enrolled older adults scheduled for elective major abdominal surgery at the Second Affiliated Hospital of Anhui Medical University from August 2021 to January 2022. The change in rSO2 from baseline was determined using the hypo-to-hypercapnic test. The main study outcome was the occurrence of postoperative delirium.ResultsA total of 101 participants were included for analysis, of whom 16 (15.8%) developed postoperative delirium. Compared with non-delirium participants, the mean arterial pressure and heart rate were not significantly different in the postoperative delirium group at T0, T1, T2, T3, T4, and T6 (all Pinteraction &gt; 0.05), but the delirium group had lower pH, lower PaO2, and higher lactate levels at T4, T5, and T6 (all Pinteraction &lt; 0.05). rSO2 at T0, T1, T2, T3, T4, and T6 was 69.0 (63.2–75.2), 70.7 ± 7.3, 68.2 ± 7.5, 72.1 ± 8.0, 69.9 ± 7.8, 67.4 ± 7.2, and 71.7 ± 8.1, respectively. The postoperative change in rSO2 during the hypercapnia test (TΔrSO2%) was 6.62 (5.31–9.36). Multivariable analysis showed that the Cumulative Illness Rating Scale (odd ratio, OR = 1.89, 95% confidence interval, CI: 1.10–3.25, P = 0.021), preoperative albumin levels (OR = 0.67, 95% CI: 0.48–0.94, P = 0.022), rSO2 at T4 (OR = 0.61, 95% CI: 0.41–0.89, P = 0.010), and postoperative TΔrSO2% (OR = 0.80, 95% CI: 0.66–0.98, P = 0.028) were independently associated with postoperative delirium in older adults undergoing elective abdominal surgery.ConclusionThe rSO2 measured at T4 and postoperative TΔrSO2% were independently associated with postoperative delirium in older adults undergoing elective abdominal surgery.
Healthcare professionals' perception and satisfaction with mental health tele-medicine during the COVID-19 outbreak: A real-world experience in telepsychiatry
Authors: Roncero Carlos , Remon-Gallo Diego , Casado-Espada Nerea , Aguilar Lourdes , Gamonal-Limcaoco Sinta , Gallego María Teresa , Bote Berta , Montejo Angel Luis , Buch-Vicent Barbara 
Published: November 2022

BackgroundThe use of telemedicine is increasingly being implemented, showing numerous benefits over other methods. A good example of this is the use of telemedicine following the breakdown caused by the COVID-19 pandemic. Previous experiences with telemedicine (TM) have not been significantly explored in relation to the professionals' own perspectives.ObjectiveIdentify and explore the perceptions and interests of mental health professionals who have performed TM during the period of pandemia.MethodsA questionnaire on mental health professionals' perceptions of and satisfaction of TM, the Font Roja Work Satisfaction Questionnaire, was adapted and used. Data collected included 112 Psychiatric Service professionals who conducted TM in March 2020, after the country had been under lockdown for 10 weeks. Over 12.000 medical consultations were carried out by the phone, showing an overwhelming response to this method.ResultsHigh levels of satisfaction were recorded amongst professionals. TM would function as a complement to the traditional system of face-to-face visits (n-112, f-109, 96.5%). Only 9.7% (f-11) believed that digital or virtual interventions would completely replace face-to-face visits. 60.8% did not consider this monotonous work. The older the health workers were, the more satisfied they felt during their follow-up telephone consultation. The greater the previous experience, the more satisfaction was shown. There were gender differences: female mental health workers reported a greater level of comfort.ConclusionTM can be implemented with less effort, but it requires time, methods, and resources to be managed. Satisfaction among professionals is high, especially among those with more clinical experience. Patient satisfaction must be contrasted against this.
Core functions and forms of Bright IDEAS: A multi-methods evaluation of the adoption of an evidence-based psychosocial training program through iterative adaptation
Authors: McNeal Demetria M. , Sahler Olle Jane Z. , Noll Robert B. , Fairclough Diane L. , Voll Megan E. , Bhat Shubha , Morrato Elaine H. 
Published: November 2022

BackgroundDespite efforts to widely disseminate interventions designed to increase access to quality supportive care to pediatric cancer patients and their families, many of these interventions fail to meet expectations once deployed in real-life clinical settings. This study identifies the functions and forms of Bright IDEAS: Problem-Solving Skills Training, an evidence based psychosocial intervention for caregivers of children recently diagnosed with cancer, to identify pragmatic program adaptations in its real-world clinical implementation. We compare intervention adoption before and after adaptations to the Bright IDEAS training program as part of a national training program designed to disseminate the intervention.Methods209 pediatric psychosocial oncology practitioners representing 134 unique institutions were trained during 10 in-person 8-hour workshops (2015–2019). Functions and forms of Bright IDEAS were identified, and adaptations made to the training agenda and curriculum based on practitioner feedback following implementation in local institutions. Mixed method evaluation included longitudinal surveys at 6- and 12-months post training; and qualitative interviews among a subgroup of practitioners (N = 47) to understand and compare perspectives on intervention adoption and barriers to implementation before and after adaptations to the Bright IDEAS training program. The RE-AIM framework was used to guide dissemination evaluation.ResultsA total of four adaptations were tailored to the identified forms of the intervention: case studies; pre-training reading materials; training videos; and letters of institutional support from primary supervisor. Pre- and post-training adaptations to the Bright IDEAS training program were mapped to RE-AIM constructs. Quantitative findings demonstrate that adaptations appeared to improve adoption and usage overall.ConclusionThis study provides insight into how contextual factors influence psychosocial practitioners' capacity to adopt, implement, and maintain Bright IDEAS in the clinical setting. This study demonstrates the use of real-time stakeholder feedback to guide intervention translation from research to practice settings.
Analisis Waiting Time, Kualitas Pelayanan dan Kepercayaan terhadap Loyalitas dengan Kepuasan sebagai Pemediasi
Authors: Ardoni Ardoni 
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh waiting time, kualitas pelayanan dan kepercayaan terhadap loyalitas pasien dengan menggunakan kepuasan pasien sebagai variabel intervening. Pada penelitian ini, objek yang digunakan adalah Rumah Sakit Paru Sumatera Barat. Cara penentuan sampel menggunakan rumus Slovin dengan metode simple random sampling sehingga dari 8.322 populasi diperoleh sampel sebanyak 100 pasien. Data pada penelitian ini dianalisis dengan teknik analisis jalur. Hasil penelitian berhasil membuktikan bahwa: waiting time berpengaruh positif dan signifikan terhadap kepuasan pasien, kualitas pelayanan berpengaruh positif dan signifikan terhadap kepuasan pasien, Kepercayaan berpengaruh positif dan signifikan terhadap kepuasan pasien,waiting time berpengaruh positif dan signifikan terhadap loyalitas pasien, kualitas pelayanan berpengaruh positif dan signifikan terhadap loyalitas pasien, kepercayaan berpengaruh positif dan signifikan terhadap loyalitas pasien, kepuasan pasien berpengaruh positif dan signifikan terhadap loyalitas pasien.
Hubungan Penggunaan Obat-obatan Antihipertensi dengan Terjadinya Xerostomia
Authors: Supit Keynes Y. , Wowor Vonny N. S. , Mintjelungan Christy N. 
Published: November 2022

Abstract: The use of antihypertensive drugs in addition to controlling high blood pressure, but can also cause side effects inter alia xerostomia, a sign or symptom of dry mouth felt by a person. This study aimed to determine the relationship between the use of antihypertensive drugs with the occurrence of xerostomia. This was a literature review study using databases of Google Scholar, PubMed and ScienceDirect. Literatures were selected through inclusion and exclusion criteria and a critical appraisal was carried out. The results obtained five literatures. There was an effect of using antihypertensive drugs amlodipine and captopril on the occurrence of xerostomia, however, there was no significant difference in the amount of respondents’ saliva (p>0.05). Antihypertensive drugs amlodipine (93.33%) and captopril (83.33%) both caused a decrease in salivary flow rate. A small proportion (29%) of respondents using antihypertensive drugs experienced xerostomia. There was a higher prevalence of xerostomia in respondents using antihypertensive drugs compared to those who did not use antihypertensive drugs (p<0.05). From 100% of xerostomia patients, there were 38.46% taking antihypertensive drugs. In conclusion, there is a relationship between the use of anti-hypertensive drugs and the occurrence of xerostomia.Keywords: xerostomia; hypertension; antihypertensive drugs Abstrak: Penggunaan obat antihipertensi di samping dapat mengontrol tekanan darah tinggi, namun dapat juga menimbulkan efek samping, salah satunya ialah xerostomia. Penelitian ini bertujuan untuk mengetahui hubungan penggunaan obat–obatan antihipertensi dengan terjadinya xerostomia. Jenis penelitian ialah literature review menggunakan database Google Scholar, PubMed dan ScienceDirect. Literatur diseleksi melalui kriteria inklusi dan eksklusi serta dilakukan critical appraisal sehingga diperoleh lima literatur. Hasil penelitian mendapatkan adanya pengaruh penggunaan obat antihipertensi amlodipin dan katopril terhadap terjadinya xerostomia, namun tidak terdapat perbedaan bermakna antara jumlah saliva pada responden yang mengonsumsi obat amlodipin dan kaptopril. Pada responden yang menggunakan obat anti hipertensi amlodipin (93,33%) dan kaptopril (83,33%) terdapat laju aliran saliva yang menurun. Sebagian kecil responden (29%) pengguna obat antihipertensi mengalami xerostomia. Prevalensi xerostomia lebih tinggi pada responden pengguna obat antihipertensi dibandingkan yang tidak menggunakan obat antihipertensi (p<0,05). Dari 100% penderita xerostomia, terdapat 38,46% yang mengonsumsi obat antihipertensi. Simpulan penelitian ini ialah terdapat hubungan antara penggunaan obat anti hipertensi dengan terjadinya xerostomia. Kata kunci: xerostomia; hipertensi; obat antihipertensi
ANALISIS PERBEDAAN KINERJA KEUANGAN SEBELUM DAN MASA PANDEMI COVID 19 DI BERBAGAI SUB SEKTOR INDUSTRI MANUFAKTUR
Authors: FUJIANTI LAILAH 
Published: November 2022

Penelitian ini bertujuan menganalisis perbedaan kinerja keuangan dari segi likuiditas, leverage dan profitanilitas sebelum dan saat pandemic covid-19 pada 3 (tiga) sub sektor industri dalam perusahaan manufaktur yang terdaftar di Bursa Efek Indonesia tahun 2019 – 2020. Tiga sub sektor tersebut meliputi industri aneka industri, industri dasar dan kimia serta industri barang konsumsi. Sampel penelitian dikoleksi berdasarkan metode purposive sampling dan berdasakan hal tersebut jumlah sampel masing- masing industri adalah 27, 54 dan 58 perusahaan. Hasil penelitian menunjukkan tidak ada perbedaan signifikan kinerja keuangan dari likuiditas dan leverage sebelum dan masa pandemic covid 19 pada tiga sub sektor industri tersebut. Akan tetapi dari segi profitabilitas menunjukkan hasil yang bervariasi. Kinerja keuangan profitabilitas pada sektor industri aneka industri dan industri barang konsumsi ada perbedaan signifikan sedangkan pada industri dasar dan kimia tidak terjadi perbedaan signifikan sebelum dan masa pandemic covid 19. Kinerja keuangan dari profitabilitas meningkat pada sub sektor aneka industri sedangkan di sub sektor barang konsumsi mengalami penuruan sebelum dan masa pandemic covid.
Key words: Kinerja keuangan, likuiditas, leverage, profitabilitas, manufaktur
ANALISIS FAKTOR-FAKTOR YANG MEMENGARUHI IMPOR CENGKIH INDONESIA
Authors: Hasibuan Almanico Islamy , Syaukat Yusman , Falatehan A. Faroby 
Published: November 2022

ABSTRACTOne of plantation commodities that has potential to become a source of foreign exchange for Indonesia is cloves (Syzigium aromaticum L. Marr. and Perr.). National cloves production fluctuates, so that in cloves production it is known as the big, medium, and small harvest. The clove cigarette industry is the main consumer because it absorbs 95% of the national clove production which is used as the main raw material in producing. This causes the volume of cloves to exported reduced. Apart from being a clove exporting country, Indonesia also imports. Cloves used in this study are cloves with the (HS) code 0907 (Whole fruit, cloves, and stems). Indonesia imports cloves to meet domestic demand, especially from the cigarette industry. Appropriate government policies related to cloves import are important, so that supply of cloves in both domestic and world markets is met. Therefore, this study aims to analyze the development of Indonesia's clove and trade policy and its implications for volume and value of clove imports.
Key words: Cloves import, cloves import policy, Cochrane-Orcutt method, Ordinary Least Squares (OLS).
ABSTRAKSalah satu komoditas perkebunan yang berpotensi menjadi sumber devisa Indonesia adalah cengkih (Syzigium aromaticum L. Marr. and Perr.). Produksi cengkih nasional sering mengalami fluktuasi, sehingga dikenal panen raya, panen sedang, dan panen kecil. Industri rokok kretek merupakan konsumen utama cengkih karena menyerap 95% produksi cengkih nasional yang digunakan sebagai bahan baku utama dalam berproduksi. Selain sebagai negara pengekspor cengkih, Indonesia juga melakukan impor cengkih. Cengkih dalam penelitian ini menggunakan cengkih dengan kode (HS) 0907(Whole fruit, cloves, and stems). Indonesia melakukan impor cengkih untuk memenuhi permintaan domestik. Kebijakan pemerintah yang tepat terkait impor cengkih sangat penting agar persediaan cengkih baik di pasar domestik maupun pasar dunia terpenuhi. Oleh karena itu, penelitian ini bertujuan untuk menganalisis perkembangan cengkih dan kebijakan impor cengkih Indonesia dan implikasinya terhadap volume dan nilai impor cengkih.
Kata kunci: Impor cengkih, kebijakan impor cengkih, metode Cochrane-Orcutt, Ordinary Least Squares (OLS).
Analisis Penggunaan Ejaan Bahasa Indonesia (EBI) Dalam Teks Eksplanasi Siswa Kelas XI SMA Ekasakti Padang
Authors: Marisya Susanti , Putri Neza Eka 
Published: November 2022

Penelitian ini dilatarbelakangi oleh banyaknya peserta didik yang mengabaikan penulisan yang menggunakan ejaan bahasa Indonesia yang benar dan mengangap bahwa ejaan tidak perlu diterapkan dalam penulisan. Peserta didik terbiasa menulis tanpa memperhatikan ejaan yang benar sehingga tulisan yang dihasilkan siswa kurang efektif. Adapun tujuan dari penelitian ini, yaitu untuk mendeskripsikan pemakaian ejaan bahasa Indonesia, yang ditinjau berdasarkan pemakaian huruf, pemakaian tanda baca, dan penulisan kata depan. Penelitian ini merupakan penelitian kualitatif dengan metode deskriptif. Sumber data dari penelitian ini adalah hasil tulisan teks eksplanasi siswa kelas XI SMA Ekasakti Padang berjumlah 30 teks. Data penelitian berupa huruf, kata, dan klausa dari teks eksplanasi yang memakai ejaan bahasa Indonesia yang benar dan salah. Pengumpulan data dilakukan dengan mengumpulkan hasil tulisan teks eksplanasi siswa yang kemudian dianalisis berdasarkan aspek yang diteliti. Analisis data menggunakan teknik reduksi data, penyajian data, dan kesimpulan. Teknik pengabsahan data menggunakan teknik sumber dan teori.
Berdasarkan temuan penelitian dapat disimpulkan. Pertama, kesalahan penggunaan huruf kapital menjad hal yang paling sering dlakukan siswa karena siswa kurang memahami kaidah penggunaan ejaaan bahasa Indonesia yang benar. Kedua, kesalahan penggunaan tanda baca juga dilakukan siswa dalam penulisan. Penempatan tanda titik dua dan tanda koma menjadi hal yang sering dilakukan siswa dalam menulis. Ketiga, penulisan preposisi menjadi hal yang sering dilakukan siswa karena siswa tidak mampu memahami penggunaan dan penulisan preposisi.
Evaluation of Retinal Nerve Fibre Layer and Macular Thickness in Amblyopia
Authors: Subedi Santosh , Baba Shrestha Jyoti , Kumar Sharma Anand , Sapkota Jyoti 
Published: November 2022

Introduction: Amblyopia is reduced visual acuity in one or both eyes due to abnormal visual development in early part of life. Purpose of this study was to evaluate and compare the retinal nerve fibre layer (RNFL) and central macular thickness (CMT) between amblyopic and fellow (normal) eyes using spectral-domain optical coherence tomography (SD-OCT).
Methods: This was a hospital based, cross-sectional comparative study conducted in the department of Ophthalmology, B.P. Koirala Lions Centre for Ophthalmic Studies (BPKLCOS), Institute of Medicine (IOM), Tribhuvan University Teaching Hospital (TUTH). All consecutive cases of age ≥5 years and ≤15 years diagnosed with unilateral amblyopia from January 2013 to June 2014 were included in this study. RNFL and macular thicknesses were measured using SD-OCT and compared between fellow eyes.
Results: A total of 32 cases with unilateral amblyopia, 19 with hypermetropic anisometropic, 4 with myopic anisometropic and 9 with strabismic amblyopia were enrolled in the study. The mean age of presentation was 9.75±2.77 years. The mean CMT in amblyopic eyes (241±45.27 μm) was significantly greater than the normal fellow eyes (233.22±44.24 μm), p= 0.042. The difference remained significant in hypermetropic anisometropic group but not in myopic anisometropic and strabismic group. The mean RNFL thickness was similar in amblyopic (104.16±13.64 μm) and fellow eyes (104.03±13.06 μm).
Conclusions: The CMT was significantly greater in the amblyopic eyes than the normal fellow eyes. There was no significant difference in the RNFL thickness between the amblyopic and normal eyes.
Profile of Colorectal Cancer at Sanjiwani General Hospital, Gianyar Period January 2020 – June 2022
Authors: Seri Mahayanti Ni Kadek , I Wayan Eka Saputra  
Published: November 2022

Background: Colorectal cancer is one of the most common cancers worldwide and the third leading cause of cancer death in the UK and the United States. There were 1.8 million new colorectal cancer cases and 881,000 deaths. This study aims to determine the profile of colorectal cancer at Sanjiwani General Hospital for the period January 2020 - June 2022.
Methods: This study is a descriptive study using secondary data from archives at the Anatomical Pathology Installation of the Sanjiwani General Hospital for the period January 2020 – June 2022. Data collection in the form of gender, age, cancer location, and histopathological type was carried out using the convenient purposive sampling method.
Results: This study showed that the highest age group was the age group 61-70 years 32.6%, the sex was mostly male 63.9% with the most common location of colorectal cancer found in the rectum 66.2% and the histopathological type in the form of adenocarcinoma 96.5%.
Conclusion: Most of the cases were found in the male gender, and the age range was 61-70 years. Most cancer locations were found in the rectum with the histopathological type of adenocarcinoma.