bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns and contexts of anti-COVID-19 vaccination in Romanian local communities
Authors: Sandu Dumitru 
Published: September 2022

Abstract
Background. Are local communities relevant units for the analysis of anti-COVID 19 vaccination? This is the question we are addressing here for the case of Romania as an Eastern European society.
Methods. To answer the question we used multiple regression models to predict cumulative rates of vaccination in rural communes and cities or towns of the country. The same relations among vaccination rates and several predictors were analysed not only in all the localities of the country but also in historical regions and urban versus rural areas. The national context of vaccination is reconstructed by survey data.
Results. Infection rates, the average age of the local population, population density and local human development proved to be rather stable predictors. Communities with higher vaccination rates are mostly urban, higher developed, with an older population, and also with higher rates of COVID-19 infections. Once local communities are placed in their regional context, significant differences emerge. Cultural areas of the country differentiate not only the intensity but also the sense of causal/prediction relations. A high number of emigrants abroad from the community, for example, reduces the intensity of vaccination against COVID-19 if one considers all the localities. The picture changes if one considers the same relation by historical regions. Some regional patterns of favouring or disfavouring the intensity of vaccination could not be interpreted with the available data.
Conclusions and discussion. Some variables are efficient discriminators of the vaccination behaviour irrespective of individual or aggregated level of the data. This is the case of age. If one considers only aggregated data at the community level in Romania, one can add infection rates and local development levels as invariant predictors acting beyond context: higher infection rates with COVID-19 and higher levels of development bring, statistically speaking, higher levels of vaccination in local communities.
Evaluation of oxidative stress, compositional and biochemical changes in milk and serum of cows with subclinical mastitis
Authors: Yehia Shimaa Ghanem , Ramadan Eman Shawky , Saad Mena , mosallam tarek , Abdel-Mobdy Ahmed , Eissa Ashraf Megahed , Aly Hanaa , Salem Noha Youssef 
Published: September 2022

Abstract
Twenty-five apparent healthy multiparous Holstein cows were examined for subclinical mastitis (SCM). The objectives of the study were to investigate the consequences of SCM on milk composition & blood biochemistry, oxidative stress biomarkers, and the correlation between different milk and serum parameters in SCM-affected cows. The cows were grouped as 16 subclinical infected and 9 healthy according to MSCC and California Mastitis Test (CMT) scores. The blood and milk samples were gathered from each animal and evaluated for compositional, biochemical, and oxidative stress markers alterations. SCM-affected milk samples showed a significant decrease in fat %, protein %, lactose %, TS %, SNF %, and total antioxidant capacity (TAC) and a significant increase in ash %, catalase, and malondialdehyde (MDA) compared with SCM-free milk samples. Milk somatic cell count showed a positive correlation with MDA and catalase. Catalase correlated positively with MDA and TAC. Milk fat showed a positive correlation with lactose, total protein, and albumin and a negative correlation with MSCC, MDA, TAC, and catalase. Significant increase in catalase and total protein associated with a significant decrease in Ca level was recorded in SCM blood samples compared with healthy counterparts. The total protein showed a positive relation with somatic cell count and albumin. Albumin correlated positively with TAC & catalase and negatively with Mg. The results indicate that a significant correlation between different parameters in blood and milk can be useful as a proper clinical indicator for the early detection of SCM in cows.
Modelling the Impacts of Climate Change on Agriculture Production in East Africa: Evidence from Heterogeneous Panel Cointegration Analysis
Authors: Abdi Abdikafi Hassan , Warsame Abdimalik Ali , Sheik-Ali Ibrahim Abdukadir 
Published: September 2022

Abstract
This study investigates the effects of climate change on cereal crop production in nine East African nations between 1990 and 2018. The study implemented pooled mean group (PMG) approach to examine the long-run and short-run dynamic impacts of the varying climatic circumstances on the output of cereal crops. Besides, the study utilized the Dumitrescu–Hurlin panel causality test to determine the causal path of the climate indicators, control variables, and cereal crop production. The results of the PMG estimator revealed that rainfall and carbon emissions have favourable and significant long-run effects on cereal crop output, even though their short-run impacts are negligible. Additionally, cultivated land area and rural population have a constructive role in enhancing agricultural output both in the long-run and short-run. However, average temperatures have negative repercussions on cereal crop production in the long-run and short-run, even though the magnitude of sensitivity is greater in the short-run. Dynamic ordinary least squares (DOLS) and fully modified ordinary least squares (FMOLS) validated the robustness of the long-run findings of the PMG technique. The causality results revealed that cereal crop output has a bidirectional causality with temperature, carbon emissions and cropped area. The study further demonstrated unidirectional causation from rural population to cereal crop yield. Therefore, the study recommends the adoption of climate-resilient agricultural practices that diminish the magnitude of adverse climatic events. The governments should also develop water retention facilities to irrigate the rainfall-reliant farms in arid land during dry seasons.
Genetic influence on choroidal vascularity index: the healthy twin study
Authors: Yoon Je Moon , Gil Yong Jin , Sung Joohon , Ham Don-Il , Kong Mingui 
Published: September 2022

Abstract
This study aimed to investigate the heritability of genetic influence on macular choroidal vascularity index (CVI). This was a cross-sectional healthy twin study. We included 373 Korean adults with healthy eyes from 79 families. CVI, Total choroidal area (TCA) and luminal area (LA) were measured using horizontal scan of spectral-domain optical coherence tomography with enhanced depth imaging. Characteristics of the participants were investigated (age, gender, drinking habits, smoking status, axial length, hypertension, and diabetes). The correlations of these characteristics with CVI were assessed using univariate and subsequently multivariate regression models. Participants who were older and had a higher intraocular pressure, higher diastolic blood pressure, and lower pulse pressure showed associations with lower CVI (p < 0.001, p = 0.014, p = 0.005, and p = 0.015, respectively). The covariate-adjusted heritability (±standard error) of the CVI was 0.716 ± 0.091, and the heritabilities of the TCA and LA were 0.691 ± 0.089 and 0.634 ± 0.100, respectively. The CVI, TCA, and LA are highly heritable.
The (Electro)Chemistry of Ethylene Carbonate, Water and HF at the Negative Electrode in Li-ion Batteries
Authors: Zorko Milena , Haering Dominik , Connell Justin , Wan Hao , Svane Katrine , Genorio Bostjan , Martins Pedro Farinazzo Bergamo Dias , Lopes Pietro , Gould Brian , Maglia Filippo , Jung Roland , Stamenkovic Vojislav , Castelli Ivano , Markovic Nenad , Rossmeisl Jan , Strmcnik Dusan 
Published: September 2022

Abstract
Compared to aqueous electrolytes, the fundamental understanding of the chemical and electrochemical processes occurring in non-aqueous electrolytes in general is far less developed. This is no different for Li-ion battery (LiB) electrolytes, where many questions regarding the solid electrolyte interphase (SEI) on the anode side remain unanswered, including its chemical composition, the mechanism of formation and the impact on LiB performance. Here, we present a detailed experimental and theoretical study of the electrochemistry of ethylene carbonate (EC) and its chemical relationship with trace amounts of water and HF across a vast range of electrode materials, from well-ordered single crystals to realistic graphite electrodes. We reveal the electrocatalytic nature of EC, HF and water electroreduction at all interfaces. Moreover, we show that these reactions are connected in a closed cycle by chemical reactions, that take place either at the interface or in the bulk of the electrolyte. For the first time, we unveil the catalytic role of water in EC electroreduction and demonstrate that the composition of the SEI depends predominantly on the balance between the (electro)chemistry of EC, water and HF.
How much does Mexico really pay for regulation in oil products transportation?
Authors: Jiménez-Pérez Alan Israel , Ortiz-Arango Francisco 
Published: September 2022

AbstractThe new oil derivatives transportation scheme proposed by the 2013 Mexican Energy Reform allowed new participants to enter the sector. The new legal framework requires fulfilling many requirements and corresponding duties for the transportation of oil products. Currently, the Mexican government already has an institution dedicated to measuring each federal procedure's regulatory cost. This work aims to quantify the regulatory costs associated with the procedures and their compliance to obtain permits for the transportation of oil products by truck. We use the standard cost method to measure these costs considering all associated costs. The results showed that two government offices did not adequately measure these costs. They do not consider relevant information on frequency and opportunity costs, resulting in undervaluation and leading to wrong expectations. As a result of this research, we provide a more accurate way of estimating these costs, which brings greater certainty in the budgeting of these projects and, therefore, increases the probability of survival and success. JEL classification: H83, K23, O13.
Genetic continuity, isolation, and gene flow in Stone Age Central and Eastern Europe
Authors: Mattila Tiina , Svensson Emma , Juras Anna , Günther Torsten , Kashuba Natalija , Ala-Hulkko Terhi , Chyleński Maciej , Pospieszny Łukasz , Constantinescu Mihai , Rotea Mihai , Palincaș Nona , Wilk Stanisław , Czerniak Lech , Kruk Janusz , Łapo Jerzy , Makarowicz Przemysław , Potekhina Inna , Soficaruc Andrei , Szmyt Marzena , Szostek Krzysztof , Götherström Anders , Storå Jan , Netea Mihai , Nikitin Alexey , Persson Per , Malmström Helena , Jakobsson Mattias 
Published: September 2022

Abstract
The genomic landscape of Stone Age Europe was shaped by multiple migratory waves and population replacements, but different regions do not all show the same patterns. To refine our understanding of the population dynamics before and after the dawn of the Neolithic, we generated and analyzed genomic sequence data from human remains of 56 individuals from the Mesolithic, Neolithic and Eneolithic across Central and Eastern Europe. We found that Mesolithic European populations formed a geographically widespread isolation-by-distance zone ranging from Central Europe to Siberia, which was already established 10 000 years ago. We also found contrasting patterns of population continuity during the Neolithic transition: people around the lower Dnipro Valley region, Ukraine, showed continuity over 4 000 years, from the Mesolithic to the end of Neolithic, in contrast to almost all other parts of Europe where population turnover drove this cultural change, including vast areas of Central Europe and around the Danube River.
Crystal Structure and Triboluminescence of Europium(Iii) Tetrakis-thenoyl Trifluoroacetonate With Outer-sphere Organic Cation
Authors: Bukvetskii Boris V. , Petrochenkova Natalya V. , Mirochnik Anatolii G. 
Published: September 2022

Abstract
A novel complex of Eu(III) tetrakis-thenoyltrifluoroacetonate with the outer-sphere cation 2-(E)-1-(2-thenoyl)ethylidene)-1-hydrazine carboxyimidoamide (Q) of the composition Q[Eu(ТТА)4]·H2O (TTA – thenoyltrifluoroacetonate-ion, Q – outer-sphere cation) characterized with intense luminescence and triboluminescence has been synthesized. The structure of the centrosymmetric crystal is composed of complex anions of the composition [Eu(TTA)4]¯, which are stacked in layers parallel to the plane (100), whereas interlayers of organic cations are located between the layers. A structural model for the formation of triboluminescent properties has been suggested.
Basal glutamate in the hippocampus and the dorsolateral prefrontal cortex in schizophrenia: Relationships to cognitive proficiency investigated with structural equation modeling
Authors: Stanley Jeffrey , Daugherty Ana , Gorey Claire Richter , Thomas Patricia , Khatib Dalal , Chowdury Asadur , Rajan Usha , Haddad Luay , Amirsadri Alireza , Diwadkar Vaibhav A. 
Published: September 2022

Abstract
Schizophrenia (SCZ) is characterized by deficits across multiple cognitive domains presumed to be associated with altered glutamate (Glu) related neuroplasticity in the dorsolateral prefrontal cortex (dlPFC) and the hippocampus. However, how Glu deficits, are related to cognition in SCZ, and whether the relationship between Glu and cognition is different in patients compared to controls has not been systematically addressed. To address these questions, here we acquired proton magnetic resonance spectroscopy (¹H MRS) from the dlPFC and hippocampus at 3T in 44 SCZ and 39 age- and sex-matched adult controls. The ¹H MRS data were acquired under behavioral constraint (passive viewing of a visual stimulus) reducing signal heterogeneity that results from processes like mind wandering. In parallel, a comprehensive cognitive assessment battery (working memory, episodic memory, and processing speed) was acquired in all subjects. We investigate inter-group differences in neurochemistry and mediation/moderation effects between glutamate–cognition relationships using structural equation modelling (SEM). SCZ were characterized by lower Glu and myo-Inositol levels from the hippocampus (p=.0044 and p=.023), with non-significant reductions in the dlPFC. Patients showed significantly poorer performance across all three cognitive domains (p<.0032). Finally, while SEM analyses demonstrated no relationship between SCZ-related hippocampal deficits and cognition, a moderation analyses revealed inter-group differences in the degree of association between right dlPFC Glu levels and processing speed. Glu and myo-Inositol deficits from the hippocampus in SCZ are consistent with the evidence of a reduced neuropil density related to the glutamatergic system. More notably, the SEM analyses indicate that hippocampal Glu deficits in SCZ were not driven by poorer cognitive ability. In SCZ, altered neurochemistry of the hippocampus acquired in a passive state does not appear to predict altered cognition. We suggest that task-based ¹H functional MRS is a more meaningful framework for investigation relationships between neurochemistry and cognition in SCZ.
Magnetogenetic closed-loop reduction of seizure activity in a rat model of epilepsy
Authors: Metto Abigael , Gilad Assaf , Pelled Galit 
Published: September 2022

Abstract
On-demand neurostimulation has shown success in epilepsy patients with pharmacoresistant seizures. Seizures produce magnetic fields that can be recorded using magnetoencephalography. We developed a new closed-loop approach to control seizure activity based on magnetogenetics using the electromagnetic perceptive gene (EPG) that encodes a protein that responds to magnetic fields. The EPG transgene was expressed in inhibitory interneurons under hDlx promoter and kainic acid was used to induce acute seizures. In vivo electrophysiological signals were recorded. We found that hDlx EPG rats exhibited a significant delay in the onset of first seizure (1142.72 ± 186.35s) compared to controls (644.03 ± 15.06s) and significantly less seizures (4.11 ± 1.03) compared to controls (8.33 ± 1.58). These preliminary findings suggest that on-demand activation of EPG expressed in inhibitory interneurons suppress seizure activity, and magnetogenetics via EPG may be an effective strategy to alleviate seizure severity in a minimally invasive, closed-loop and cell-specific fashion.
Changes in nutritional characteristics and performance of grazing Nellore cows during the peripartum phase receiving or not protein supplementation
Authors: DAVID GABRIEL SANTOS SOUZA , Matos Éllem Maria de Almeida , Domingos Bianca Rodrigues , Sousa Luiz Carlos Oliveira , Lopes Sidnei Antônio , Paulino Mario Fonseca , Filho Sebastião de Campos Valadares 
Published: September 2022

AbstractWe objective was to understand the changes in nutritional characteristics and performance of grazing Nellore cows during the peripartum receiving or not supplementation. Forty multiparous cows were used, divided into two treatments: CON - mineral mixture and SUP – protein supplementation. Digestibility trial was performed (-45,-30,-15, + 20, +40; days relative to calving). The average daily gain (ADG) pre and postpartum of the cows were measured and, in gestational and maternal tissues in the prepartum, in addition of body condition score (BCS). The calves were weighed at birth and at 30 days of age. There was an effect of treatment and period (P ≤ 0.10) for dry matter, organic matter and crude protein intake, while forage intake was similar (P ≥ 0.10), but with a period effect (P ≤ 0.10). There was 14.37% decrease in dry matter intake from day − 30 to day − 15 of prepartum. In the postpartum period, at 20 days of lactation, there was increase of 72.66% in relation to the period − 15. There was interaction between period and treatment for all digestibilities (P ≤ 0.10). No differences were observed in postpartum ADG (P ≥ 0.10), BCS at calving and postpartum (P ≥ 0.10). However, higher total ADG and in maternal tissues (P ≤ 0.10) were observed on supplemented animals, but with ADG in gestational tissues similar (P ≥ 0.10). It is concluded that there is a decrease in voluntary intake in grazing pregnant cows close to parturition and greater performance of animals supplemented in prepartum.
Multi-Domain Characterization and Rapid Detection Technology for Cocaine and Methamphetamine Acute Abuse based on EEG
Authors: Xia Jie , Wu Jintao , Pan Jiadong , Zhang Fan , Jin Hao , Dong Shurong , Wang Yueming , Luo Jikui , Si Ke 
Published: September 2022

Abstract
Multi-domain characterization and a new fast detection method for acute illegal psychostimulants abuse detection based on waking-state EEG of mice is proposed in this paper. To get corftical electroencephalogram (EEG), three groups of mice were injected with cocaine (Coca), methamphetamine (Meth), and saline (Sali) respectively following the experimental paradigm of drug abuse. The EEG features were extracted out by multi-domain views, including time, frequency, complexity, dynamics, and independent domains to obtain acute drug abuse effects on the brain. New strategy combing time domain with frequency domain is developed as multi-domain input and by means of dimension transformation approach preserving temporal information, the performance of drug abuse detection is greatly improved with deep learning models of ResNet50. Results show that comparing to support vector machine (SVM), k nearest neighbor (kNN), random forest (RF), and long short-term memory fully convolutional networks (LSTM-FCN), ResNet50 based on our proposed multi-domain features has best F1-score of 95.10%. This promising method provides a low-cost, fast, and widely assisted technology for psychostimulants abuse identification.
Clinical efficacy and safety of sirolimus in childhood-onset systemic lupus erythematosus in real world
Authors: Zhang Lei , Cui jieyuan , Zhang Lin 
Published: September 2022

Abstract
Objective: To investigate the effectiveness and safety of sirolimusin childhood onset systemic lupus erythematosus (cSLE) in a real world.
Methods: This is a retrospective real world clinical study. All cSLE patients treated with sirolimus in Children's Hospital of Hebei Province China were analyzed. They were treated with sirolimus and followed up regularly. The SLEDAI-2K score, levels of anti-double-stranded DNA (anti-dsDNA) antibody, complement components C3 and C4, and corticosteroid reduction were recorded at baseline and at 6, 12, and 18 months. Adverse events were also collected.
Results: 32 patients were enrolled in the study. SLEDAI-2K were improved on all time-points (p<0.05). Complement levels increased and the levels of anti-dsDNA antibody decreased during treatment. The mean dose of prednisone tapered and achieved significant reduction after 12 months therapy (15.4 ± 5.8 mg/day to 4.8 ± 2.1 mg/day; p<0.05). Sirolimus was well tolerated and only five patients (15.6%) experienced adverse events, all of which were classified as infections (two bacterial infection and three viral infections). No deaths, severe infusion reactions, or hypersensitivity reactions were found.
Conclusions: Sirolimus decreased disease activity and tapered daily glucocorticoid dose with a good safety profile.
Southeast Asian peatland drainage emits 220 Mt of carbon per year, equivalent to 2.2% of global fossil-fuel emissions
Authors: Larson Erik , Dadap Nathan , Longo Marcos , Konings Alexandra , Xu Xiangtao , Ordway Elsa , Saatchi Sassan S , Moorcroft Paul 
Published: September 2022

Abstract
Southeast Asian peatlands are climatically important ecosystems, storing approximately 70 billion tons of carbon. Natural and human-induced droughts are lowering peatland water tables, increasing decomposition and the risk of peat-burning wildfires. The rapid nature of carbon losses arising from peatland drainage and accompanying fire-related losses compared to the slow accumulation of peat means that the effects of peatland drainage are essentially irreversible on human timescales. Here, we use a terrestrial biosphere model incorporating vertically-resolved peatland carbon and water dynamics to predict decomposition and fire in Southeast Asia as a result drainage-induced drying. The model captures observed patterns of interannual and seasonal variation in soil moisture and its soil moisture estimates are a better predictor of observed burned area fraction than either precipitation or remotely-sensed estimates of surface soil moisture (r2=0.63, 0.50, 0.56 respectively). Simulations of a fully-drained 1.4 m peat deposit emit an additional 9 tC ha-1 yr-1 and 13 tC ha-1 yr-1 from decomposition and fire respectively. The emissions from decomposition are linearly related to the depth of drainage and can reach up to 31 tC ha-1 yr-1 when fully drained. At regional scales, these estimates imply that 220 MtC yr-1, or 2.2% of global fossil fuel emissions, are being emitted from Indonesian and Malaysian peatlands due to drainage. The vulnerability of these large, concentrated carbon stocks, combined with their long timescale of accumulation, underscore the importance for preserving tropical peatlands to avoid further exacerbation of human induced climate change.