bluuebunny/crossref_metadata_2025_split huggingface dataset:
Did the first wave of the COVID-19 pandemic impact the cesarean delivery rate? A retrospective cohort study at a primary care center in Switzerland
Authors: Cincera Tabea , Conde Natalia , von Felten Stefanie , Leeners Brigitte , von Orelli Stephanie 
Published: December 2022

Abstract

Objectives
During the first 3 months of the coronavirus disease 2019 (COVID-19) pandemic, our hospital’s quality management team determined a decline in the rate of cesarean deliveries (CD). Thus, in this study we examined both the factors associated with this decrease as well as neonatal outcomes.

Methods
This was a retrospective observational cohort study comparing deliveries (n=597) between March and May 2020 (first nationwide “lockdown” in Switzerland) with those during the same period in 2018 and 2019 (n=1,063). A multivariable logistic regression analysis was used to examine the association between CD and the pandemic, adjusting for relevant risk factors for CD.

Results
The overall rate of CD during the pandemic period was lower (30.0%), than during the pre-pandemic period (38.7%, unadjusted odds ratio 0.68, 95% confidence interval [95%CI]: 0.55 to 0.84, p=0.0004) a result that was supported by the adjusted odds ratio (0.73, 95%CI: 0.54 to 0.99, p=0.04).

Conclusions
The results of this study confirmed a significant reduction in the rate of CD in early 2020, during the first lockdown period due to COVID-19, but without major differences in maternal and infant health indicators or in obstetric risk factors than before the pandemic. These results may have been due to a difference in the composition of the obstetric team as well as the behavior of the obstetrics team and in the patients during the pandemic, given the burden it placed on healthcare systems. However, this hypothesis remains to be tested in further research.
Les compétences des enseignants de traduction au XXIème siècle
Authors: Najm Pierre , Abou Fadel Saad Gina 
Published: December 2022

Abstract
In the context of a digital revolution that predicts a change of rules in different sectors of the future economy and in order to comply with the requirements of the extremely changing labor market, the education sector is faced with the big challenge of sustaining teaching quality. Competence-based training (CBT) seems to offer the best way of reaching this aim, but teaching using the CBT model requires specific teaching competences. After publishing a framework for translator and translation competences, the EMT network publishes the Translator Trainer Profile that outlines the competences that translator trainer staff should possess. The School of Translators and Interpreters of Beirut (ETIB) of Saint Joseph University of Beirut, member of the EMT network since 2019, conducted a qualitative research with the aims of identifying the teaching competences required from its teachers. This article exposes the results and the different steps undertaken in this research.
Long noncoding RNA WT1-AS regulates trophoblast proliferation, migration, and invasion via the microRNA-186-5p/CADM2 axis
Authors: Qiu Qun , Tan Juan 
Published: December 2022

Abstract
This study aimed to determine the role of long noncoding RNA (lncRNA) WT1 antisense RNA (WT1-AS) in the occurrence and progression of preeclampsia (PE) and to determine the underlying molecular mechanisms. The associations between WT1-AS and microRNA (miR)-186-5p, and miR-186-5p and cell adhesion molecule 2 (CADM2) were predicted using StarBase software and verified via dual-luciferase assays. To explore the role of the human chorionic trophoblast line HTR-8/SVneo, gene (WT1-AS/miR-186-5p) gain/loss of function experiments were performed. Qualitative reverse transcription-polymerase chain reaction (RT-PCR) analysis was used to evaluate transfection efficiency. Cell proliferation, apoptosis, cell migration, and invasion were assessed using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide (MTT), flow cytometry, and transwell analysis, respectively. Moreover, CADM2 protein expression was measured by western blotting. The results indicated that overexpression of WT1-AS inhibited cell viability, migration, and invasion, and induced apoptosis in HTR-8/SVneo cells. We observed that miR-186a-5p directly targeted WT1-AS, and miR-186a-5p knockdown reversed the effects of WT1-AS knockdown in HTR-8/SVneo cells. Binding sites were found between miR-186-5p and CADM2, and CADM2-overexpression reversed the influence of miR-186-5p mimic on HTR-8/SVneo cells. In summary, our findings demonstrated that lncRNA WT1-AS participates in PE by regulating the proliferation and invasion of placental trophoblasts, through the miR-186-5p/CADM2 axis.
The incidence of bronchiectasis in chronic obstructive pulmonary disease
Authors: Lu Hsueh-Yi , Liao Kuang-Ming 
Published: December 2022

Abstract
Bronchiectasis is a common comorbidity in chronic obstructive pulmonary disease (COPD). There are limited data regarding the incidence of bronchiectasis in COPD. The purpose of the study was to use a nationwide database to evaluate the incidence of bronchiectasis in COPD in Taiwan. We used a cohort of 2,000,000 individuals followed from 2005 to 2018. Patients with COPD diagnosed between January 1, 2011, and December 31, 2017, were selected, and those with bronchiectasis before COPD were excluded. In total, 134,366 patients with COPD were enrolled, and propensity score matching was used to ensure homogeneity of baseline characteristics between the COPD and non-COPD groups. The incidence rate of bronchiectasis was higher in the COPD group than in the non-COPD group (87.83 vs 69.80 per 10,000 person-years). The adjusted hazard ratio (1.9; 95% confidence interval 1.75–2.05; P < 0.001) of bronchiectasis indicated that the risk of bronchiectasis was 1.9 times higher for patients with COPD than for patients without COPD. In the COPD group, the age-stratified incidence rates of bronchiectasis increased with age (55.01, 80.92, 101.52, and 105.23 for 40–49, 50–59, 60–69, and over 70 years, respectively). The incidence of bronchiectasis was higher in patients with COPD than in the general population, the risk of bronchiectasis increased with age in COPD, and post-tuberculosis status was an important risk factor for bronchiectasis.
Policing a revolutionary capital: Public order and population control in Nafplio (1824–1826)
Authors: Seirinidou Vaso 
Published: December 2022

Abstract
In the new hierarchy of space created by the Greek Revolution, Nafplio acquired a prominent position and soon replaced Tripolitsa as the preeminent administrative center of the fledgling state. Declared by law as the seat of the administration in September 1823, Nafplio was a stronghold during the incessant infighting that characterized the Greek struggle for independence. From June 1824 (when its fortress was handed over to the government), Nafplio served as the political and military center of the revolutionary territory. Administrative officials, politicians, primates, soldiers, and an influx of refugees thronged the city, creating conditions for overpopulation, at a time when the Ottoman–Egyptian commander Ibrahim Pasha was advancing on rebel strongholds in the Peloponnese. Based on voluminous archival records, this essay examines the policing projects carried out by the revolutionary authorities between 1825 and 1826 to address public order and security issues facing the city. The essay demonstrates that in the space of two intense years of political and military struggle, enclosed and overcrowded Nafplio became a laboratory for developing civil administration and the creation of a policed capital.
Personen im Recht – über Rechtssubjekte und ihre Rechtsfähigkeit -
Authors: Bauermeister Tabea , Grobe Tony 
Published: December 2022

Abstract

Traditionell differenziert das deutsche System zwischen natürlichen Personen, juristischen Personen und rechtsfähigen Personengesellschaften. Gerade der Unterschied zwischen juristischer Person und rechtsfähiger Personengesellschaft ist jedoch – spätestens mit Inkrafttreten des MoPeG – überholt. Außerdem zeigen u. a. die Vorgesellschaft und der Nasciturus, dass es auch außerhalb dieser drei Gruppen Rechtsfähigkeit geben kann. Der folgende Beitrag zeigt auf, dass es keine „Rechtsfähigkeit zweiter Klasse“ gibt, sondern allein eine Kategorisierung in Rechtsobjekt und Rechtssubjekt überzeugt. Darüber hinaus wird der Frage nachgegangen, mit welchen Kriterien eine Trennlinie gezogen werden kann, um problematischen Fällen wie der Rechtsfähigkeit der wirtschaftlichen Einheit des Wettbewerbsrechts oder auch den jüngst verstärkt in den Fokus rückenden Rechten der Natur überzeugend gegenübertreten zu können.
Anomalous geoelectric potential variations observed along a gas pipeline section in Argentine, possible intensification with variations of the Earth’s magnetic field
Authors: Larocca Patricia Alejandra , Arecco M. A. , Macrino A. C. 
Published: December 2022

Significant anomalous geoelectric potential variations have been observed in a section of the NEUBA II gas pipeline along its route in the district of Saavedra, near the area of Goyena, province of Buenos Aires (Argentine), where it goes through major lithological, edaphological and hydrological variations. Detailed research was conducted, showing that these disturbances may be intensified with variations of the Earth’s magnetic field, during a magnetic storm, as the pipe-to-soil potential (PSP) values remained constant for weeks and then fluctuations from 0.1 V to 0.15 V were recorded in various parts of the pipeline. On the other hand, to provide another analysis of these variations, models based on the distributed source transmission line (DSTL) theory were used, proposing a uniform geoelectric field along the pipeline route. A design was proposed that would allow modeling the response of the pipeline to variations of induced geoelectric fields, taking into account their intensification based on points of discontinuity due to subsoil characteristics or differences in its structure. Good consistency was achieved between the observed and modeled PSPs. The analysis and monitoring of these PSPs is a useful tool to identify the potential risks caused by geomagnetically induced currents in the pipes that would increase the effects due to the structure or the environment in which it is buried.
Isolation and characterization of major degradants in dihydroergotamine injection
Authors: Basappa Praveen , MS Uma Shankar , Dama Venugopala Rao 
Published: December 2022

AbstractIn this study, we report the systematic approach for characterization of two major degradant impurities, which are not listed in any compendia and were formed during the stability studies of Dihydroergotamine mesylate injection (DHE). An ion-pair UPLC chromatographic method was developed to quantify the related substances present in the DHE injection drug product. The same was used to monitor the impurity profiling during its stability. The two unknown impurities were observed at RRT about 0.08 (Impurity-1) and RRT about 0.80 (Impurity-5) and found to be significantly increasing on stability. Forced degradation studies revealed the nature of the impurity and conditions required for enriching them. A Mass compatible HPLC method was developed to quantify only these two impurities using 25% ammonia and formic acid in water. Their mass numbers were identified using LC MS/MS with triple quadruple mass spectrometer coupled with a HPLC. These two impurities were then isolated from enriched products using preparative HPLC. These impurities were then characterized using Mass and NMR analysis along with Q-TOF elemental analysis.
Sichere und effiziente Produktion durch Agentensysteme
Authors: Heid Manuel , Pfeifer Michael , Richter Detlev , Harder Dimitri , Motsch William , Gafur Nigora , Gösling Henning , David Alexander , Thomas Oliver , Ruskowski Martin , Wagner Achim 
Published: December 2022

Im Bereich der modularen und flexiblen Produktion stellen konventionelle Ansätze für die Maschinensicherheit (Safety) Hürden in der Produktivität und Wirtschaftlichkeit dar. In diesem Artikel wird ein Konzept mit Fokus einer digitalen Produktionsplanung und -durchführung für Betreiber diskreter Produktionen entwickelt, welches die Sicherheits-Problematik durch einen Smart-Safety-Ansatz beantwortet und zur Steigerung der Effizienz der Produktion beiträgt. Im entwickelten Konzept werden verschiedene Akteure durch Softwareagenten repräsentiert, die je nach Anforderung auf wissensbasierte oder erlernte und freigegebene Nebenbedingungen zurückgreifen.
I-optimal Designs for three and four component mixture models in orthogonal blocks
Authors: Hasan Taha , Hussain Syed Adil 
Published: December 2022

In Industrial and Pharmaceutical experiments it is desired to have best predictions of the response on the basis of small amount of data. Mixture experiment generally aims to predict the response(s) for all possible mixture blends. When we compute optimal design for mixture response surface we must focus on prediction capability of the design. The conventional optimal criteria, such as D-, A- and E-optimality are not suitable for determining the prediction capability of designs. As I-optimal design minimizes the average variance of prediction over the mixture region, so it clearly focuses on prediction capability of the design. Hence I-optimal criterion seems to be more appropriate in this conjecture. In this paper we propose the construction of I-optimal mixture designs for a quadratic Scheffé’s and Darroch and Waller’s model in three and four components, using two orthogonal blocks. I-efficiency of designs is compared with the I-efficiency of D-optimal designs for Scheffé’s and Darroch and Waller’s models.
An overview of pigmented lesions of the oral cavity
Authors: Alanazi Dalal Mufadhi , Alanazi Badria Moashi , Alanazi Hilalah Masoud , Al-Shahrani Ghada Khairallah , Alanazi Abeer Abdulhai , Alenazy Tamam Mohammed , Alruwaili Amirah Hamoud , Almutairi Reem Awwadh , Alanazi Suad Murdhi 
Published: December 2022

It might be difficult to diagnose pigmented lesions of the mouth and perioral regions. Although several lesions may be correctly identified on the basis of clinical findings alone and while epidemiology may be helpful in guiding the clinician, the histological examination is typically necessary for the final diagnosis. Oral hyperpigmentation may present exogenously/ endogenously; pathologically/physiologically. The differential diagnosis depends on factors like medication usage, familial history in addition to the position, spread, and length as well as hue and pattern variations. Physiological pigmentation, melanotic macule, melanocytic nevus, smoker's melanosis, oral melanoacanthoma, pigmentation caused by foreign matter or medicines, Peutz-Jeghers syndrome, Addison's disease, and oral melanoma are examples of dark or black pigmented discolorations that can be unifocal, multifocal, or dispersed macular lesions.
Analysis of Content Validity on Mathematical Computational Thinking Skill Test for Junior High School Student Using Aiken Method
Authors: Putri Yusriyyah Febriani , Kadir Kadir , Dimyati Ahmad 
Published: December 2022

Computational thinking skills are a relevant approach to future problem-solving. Therefore, these skills need to be integrated into mathematics learning in schools. This research is part of developing mathematical computational thinking skill tests for junior high school students. In this segment, the study aims to analyze the content validity of the mathematical computational thinking skill test. The main stages in this research are define, design, and develop. Expert validation data were collected using Google Form sheets. The analysis technique used is the content validity technique with the V Aiken method. The results of the study revealed that the results of content validation through the assessment of 7 experts, developed a test specification containing 20 items that measure mathematical computational thinking skills with a coefficient (V) in the interval (0.770 – 0.920) with an average of 0.866 or very good category. The test instrument is valid for measuring decomposition indicators, pattern recognition, abstraction, algorithmic thinking, and evaluation indicators. Each indicator is measured by 4 items with a coefficient of V decomposition indicator of 0.868, pattern recognition 0.883, abstraction 0.865, algorithmic thinking 0.833, and evaluation 0.883. The study concludes that the indicators of decomposition, pattern recognition, abstraction, algorithmic thinking, and evaluation indicators are valid in measuring mathematical computational thinking skills.
Comparative Study of Mental Health among Male and Female College Students
Authors: Panda Yogamaya , Azeem Kaukab 
Published: December 2022

Introduction: These vital components of cognitive, behavioural, and emotional well-being states to mental health. Public universities mostly stress on students because of financial constraints (Shafiq S, & et al., 2020). The purpose of this investigation was to find out the gender differences on mental health (MH) in the college students.
Method: 130 participants perusing their degree courses in Arts in various colleges of Cuttack and Bhubaneswar of Odisha, India. To find out the significance mean variance among the groups t-test was considered.
Result and Discussion: The analysing data reveals that the Positive self-evaluation (P>0.05), perception of reality (P>0.05), integration of personality (P<0.05), autonomy (P<0.05), oriented attitude (P<0.05), and environmental mastery (P<0.05). The result revealed that male students are differing from female college students such as integration of personality, autonomy, group oriented attitude and environmental mastery. However, in case of positive self-evaluation and perception of reality the result is found to be insignificant.
Conclusion: It is concluded that the male college students are not differing from female college students with regard to positive self-evaluation (PSE) and perception of reality (PSE). Furthermore, concluded that the male college students are differing from female college students such as; integration of personality (IP), Autonomy dimension of MH, group oriented attitude and case of environmental mastery.
Semiotic analysis of cultural representations in Iranian English textbooks
Authors: Safari Parvin , Pourhashemi Mohammad Razagh 
Published: December 2022

The Peircean semiotic approach suggests a non-linear and dynamic view of culture to examine it through signs, sign systems and meaning-making processes. This approach emphasises that images, texts and tasks are considered semiotic resources, generating cultural meanings through semiotic processes. This study aims to reveal the concept of culture in a dynamic manner concerning the semiotic potential embedded in the Iranian EFL textbooks used in junior high schools from the perspective of a semiotic framework. Semiotic analysis showed that cultural meaning-making is directed through guided semiosis, hampering students’ exploration of cultural potential meanings, cultural reflection, understanding and awareness. The denotational and the indexical relationship between texts and images also does not foster students’ intercultural understanding of living and maintaining in a global community, and hence, teachers need to move towards the symbolic aspect of texts and images through unguided semiosis to develop students’ cultural understanding of self and others.
Keywords: Cultural, English textbooks, Peircean, semiotic, unguided semiosis;
Antibiotic effectiveness on biofilm-producing Escherichia coli isolated from catheterized patients
Authors: Gunardi Wani D , Dharmawan Ade , Layanto Nicolas 
Published: December 2022

Biofilm is one of the factors that facilitate the occurrence of catheter-associated urinary tract infection (CAUTI). Escherichia coli is reported as one of the most dominant bacteria that have virulence factors including biofilm formation. Uropathogenic E. coli (UPEC) shows increasing resistance to several antibiotics. Examination of the antibiotic sensitivity on the biofilm-producing E. coli and its activity on biofilm formation are important for selecting high effectiveness antibiotics which is beneficial for the management of CAUTI patients. A total of 35 E. coli isolates were recultured in the medium of LB agar and blood agar. The isolates were evaluated the sensitivity based on their MIC value to several antibiotics. In addition, the antibiofilm activity of the antibiotics based on their MBIC value was also evaluated. The data obtained were analyzed both descriptively and analytically. Almost the E. coli isolates have good sensitivity to meropenem antibiotics, amoxicillin-clavulanic acid, and Fosfomycin. However, among the evaluated antibiotics, only fosfomycin that showed antibiofilm activity. The different in terms of the resistance phenotype between the urinary isolates and the catheter isolates was observed. However, there were no significantly differences in the MIC value (pMIC=0.522) and the MBIC value (pMBIC = 0.523). In conclusion, the alternatives of antibiotic therapy for the planktonic bacteria are amoxicillin-clavulanic acid and fosfomycin, while for the biofilm bacteria is fosfomycin. A biofilm screening examination on the catheter to improve the effectiveness of therapy management for CAUTI patients is recommended.
Case Study of Dermatomikosis in Cats at Healthypet Clinic, Madiun
Authors: Yudistira Dio , Achmad Agung Budianto 
Published: December 2022

Dermatomycosis is generally said to be a skin disease caused by a fungus, without needing to know the species of the skin fungus. Animals are hosts for various species of pathogenic fungi that are also infective to humans. Onesources of of thetransmission of fungi to humans is mediated by pets. Transmission of fungi from one host to another can be through direct contact or through an intermediary. Dermatomycosis is a zoonotic disease. To determine the procedure, clinical symptoms, examination, and treatment of cats with dermatomycosis on outpatients at the Healthypet Veterinary Clinic. This is done by taking thedata medical recordof dermatomycosis patients from the physical examination of the animal and followed by the diagnosis from the veterinarian, after which dermatomycosis treatment is carried out. After four weeks, data was collected from observations during the last 3 years 2017-2019 on all aspects reviewed to obtain objective results. Thus, data is obtained that show the important factors that can be used to diagnose a cat infection is dermatomycosis. Dermatomycosis infestations mostly occur in humid conditions with various predisposing conditions.Therapy and medication are used to suppress the effects secondary of Dermatomycosis and also to eradicate Dermatomycosis it self.
Reef Complexes of the Late Ordovician–Early Silurian Altai Basin: Classification, Structure, Paleobiota, and Paleogeography
Authors: Sennikov N.V. , Obut O.T. , Khabibulina R.A. , Luchinina V.A. , Lykova E.V. , Tokarev D.A. , Shcherbanenko T.A. 
Published: December 2022

Abstract
—The paper presents data on the classification, structure, and biota of reef complexes from the Late Ordovician–early Silurian Altai Basin. The early Paleozoic history of the Altai Basin included the early–middle Katian, late Katian, early Hirnantian, late Telychian, and middle–late Sheinwoodian events of large-scale reef formation which produced framework reefs, mud mounds, and coral meadows. The early Paleozoic reefs of the area formed at rates of 40 to ~12 cm per thousand years. The late Telychian reef system, which formed in 0.51–1.0 Myr, occupied the largest area of the basin. The lateral extent of reef systems in the Late Ordovician–early Silurian basin of Altai depended more on the rates of vertical and lateral growth, as well as on the previous sea bottom topography and clastic inputs, than on the duration of reef formation. Carbonate deposition in the Altai basins of that time can be simulated with a general model implying formation of distal barrier reefs.