bluuebunny/crossref_metadata_2025_split huggingface dataset:
An overview of some classical models and discussion of the signature‐based models of preventive maintenance
Authors: Asadi Majid , Hashemi Marzieh , Balakrishnan Narayanaswamy 
Published: March 2022

AbstractIn reliability engineering literature, a large number of research papers on optimal preventive maintenance (PM) of technical systems (networks) have appeared based on preliminary many different approaches. According to the existing literature on PM strategies, the authors have considered two scenarios for the component failures of the system. The first scenario assumes that the components of the system fail due to aging, while the second scenario assumes the system fails according to the fatal shocks arriving at the system from external or internal sources. This article reviews different approaches on the optimal strategies proposed in the literature on the optimal maintenance of multi‐component coherent systems. The emphasis of the article is on PM models given in the literature whose optimization criteria (cost function and stationary availability) are developed by using the signature‐based (survival signature‐based) reliability of the system lifetime. The notions of signature and survival signature, defined for systems consisting of one type or multiple types of components, respectively, are powerful tools assessing the reliability and stochastic properties of coherent systems. After giving an overview of the research works on age‐based PM models of one‐unit systems and ‐out‐of‐ systems, we provide a more detailed review of recent results on the signature‐based and survival signature‐based PM models of complex systems. In order to illustrate the theoretical results on different proposed PM models, we examine two real examples of coherent systems both numerically and graphically.
Fertigteilbauweise mit Carbonbeton und Aerogel‐Wärmedämmung
Authors: Stelzmann Mario , Zocher Birgit , Pickert Ludwig , Bendl H. , Kahnt Alexander , Holschemacher Klaus 
Published: March 2022

AbstractDie Umsetzung der CUBE BOX stellt einen Meilenstein in der Entwicklung des Carbonbetonbaus im Hochbau dar. Zum ersten Mal entstand ein industriell gefertigtes Gebäude komplett aus Carbonbeton. Im Rahmen des Bauprojekts wurden Stahlbeton(halb)fertigteile in die Carbonbetonbauweise überführt. Ferner beschreibt der Beitrag die Integration von Aerogel‐Wärmedämmungen in den Betonfertigteilbau. Ausgehend von verschiedenen Problemstellungen bei der Planung der Carbonbetonbauteile sind die notwendigen Prozessschritte zur Herstellung und Montage der Halbfertigteilwände und der Fertigteildecken beschrieben. Eine besondere Herausforderung des Projekts war die Verwendung einer automatisierten Fertigungsstrecke im Betonfertigteilwerk. Im Detail erfolgt die Darstellung der wesentlichen Arbeitsschritte aus Praxissicht.
CUBE Projektvorstellung
Authors: Kupke Marén 
Published: March 2022

AbstractMit dem Projekt CUBE sind nicht nur die Entwicklung und Herstellung schlanker, tragender und wärmegedämmter Carbonbetonbauteile gelungen, sondern auch die Planung, Nachweisführung, Genehmigung und Umsetzung des weltweit ersten kompletten Gebäudes in Carbonbetonbauweise. Bei der Gestaltung des CUBE wurden zur Demonstration der breiten Einsetzbarkeit von Carbonbeton sowohl frei geformte als auch ebene Bauteile genutzt. In den nächsten Jahren wird das Gebäude umfassend untersucht, dabei stehen besonders die Erprobung und Bewertung der bauphysikalischen Eigenschaften, der Gebrauchstauglichkeit und Dauerhaftigkeit sowie der optischen Qualität im Fokus. Damit können nun der erreichte Stand der Entwicklungen in der Carbonbetonbauweise für Fachinteressierte und auch für eine breite Öffentlichkeit dargestellt, weitere Erkenntnisse zum Langzeitverhalten des Baumaterials gewonnen und die Erfahrungen und Entwicklungsergebnisse aus dem Projekt für zukünftige Carbonbetongebäude genutzt werden.
Bayesian analysis of one‐inflated models for elusive population size estimation
Authors: Tuoto Tiziana , Di Cecco Davide , Tancredi Andrea 
Published: March 2022

AbstractThe identification and treatment of “one‐inflation” in estimating the size of an elusive population has received increasing attention in capture–recapture literature in recent years. The phenomenon occurs when the number of units captured exactly once clearly exceeds the expectation under a baseline count distribution. Ignoring one‐inflation has serious consequences for estimation of the population size, which can be drastically overestimated. In this paper we propose a Bayesian approach for Poisson, geometric, and negative binomial one‐inflated count distributions. Posterior inference for population size will be obtained applying a Gibbs sampler approach. We also provide a Bayesian approach to model selection. We illustrate the proposed methodology with simulated and real data and propose a new application in official statistics to estimate the number of people implicated in the exploitation of prostitution in Italy.
Up‐recycling oil produced water as the media‐base for the production of xanthan gum
Authors: Sampaio Igor Carvalho Fontes , Jorge Louro Crugeira Pedro , de Azevedo Santos Ferreira Joalene , Nunes dos Santos Jacson , Borges Torres Lima Matos Josilene , Luiz Barbosa Pinheiro Antonio , Chinalia Fabio Alexandre , Fernando de Almeida Paulo 
Published: March 2022

AbstractProduced water (PW) and crude glycerin (CG) are compounds overproduced by the oil and biodiesel industry and significant scientific efforts are being applied for properly recycling them. The aim of this research is to combine such industrial byproducts for sustaining the production of xanthan by Xanthomonas campestris. Xanthan yields and viscosity on distinct PW ratios (0, 10, 15, 25, 50, 100) and on 100% dialyzed PW (DPW) in shaker batch testing identified DPW treatment as the best approach for further bioreactor experiments. Such experiments showed a xanthan yield of 17.3 g/L within 54 h and a viscosity of 512 mPa s. Physical‐chemical characterization (energy dispersive X‐ray spectroscopy, scanning electron microscopy and Raman spectroscopy) showed similarities between the produced gum and the experimental control. This research shows a clear alternative for upcycling high salinity PW and CG for the generation of a valued bioproduct for the oil industry.
Examining the roadblocks of circular economy adoption in micro, small, and medium enterprises (MSME) through sustainable development goals
Authors: Virmani Naveen , Saxena Prateek , Raut Rakesh D. 
Published: March 2022

AbstractThe linear economy model is being transformed into a circular model to positively impact the environment, society, business, and sustainable development goals. However, emerging economies such as India face many significant roadblocks adapting to a circular model. Therefore, this study attempts first to assess and visualize the roadblocks in circular economy adoption in Indian micro, small, and medium enterprises (MSME) and then identify and evaluate the solutions to overcome these roadblocks. This paper explores 31 critical roadblocks and proposes 14 solutions in the pathway of circular economy through extant literature and expert inputs. Graph theory matrix approach (GTMA) is applied to calculate the comprehensive circular economy roadblock index. This value signifies the intensity of roadblocks taken altogether in an industry under consideration. Furthermore, fuzzy stepwise weight assessment ratio analysis (fuzzy‐SWARA) is used to compute the weights of individual roadblocks. After that, fuzzy‐weighted aggregated sum product assessment (fuzzy‐WASPAS) is used to rank the identified solutions and efficiently implement a circular economy. Finally, the research presents sensitivity analysis and the theoretical and managerial implications of the findings.
Osteopenia in a young man associated with the use of tenofovir disoproxil fumarate
Authors: Li Chunmei , Li Hui , Gong Ming , Wei Jia 
Published: March 2022

AbstractTenofovir disoproxil fumarate is a recommended first‐line therapy for patients with chronic hepatitis B, although the frequent Tenofovir disoproxil fumarate related adverse drug reactions are nephrotoxicity and bone toxicity. We described the case of a 21‐year‐old Han Chinese male patient with chronic hepatitis B with tenofovir disoproxil fumarate‐associated osteopenia. The patient presented osteopenia at the site of his femoral neck with bone mineral density 0.865g/cm2 (Z = −1.9) in January 2020. Nine months after switching to TAF, bone mineral density at left femoral neck improved to 0.978g/cm2 (Z = −1.0) in September 2020. Bone mineral density of this patients was normal in January 2021. This is the first report in very young man presenting tenofovir disoproxil fumarate‐associated osteopenia.
Need for liver biopsy in pediatric nonalcoholic steatohepatitis diagnosis regardless of improvement in liver damage through weight loss
Authors: Kakiuchi Toshihiko , Koji Azusa , Yoshiura Masato 
Published: March 2022

AbstractLiver biopsy is recommended for obese children with fatty liver disease to ensure that nonalcoholic steatohepatitis (NASH) is not overlooked. Even in pediatric cases, regardless of the improvement in liver damage through weight loss, children should be tested and treated with the possibility of NASH in mind.
Novel 8%‐TiO2‐nanoparticle‐reinforced dense polycrystalline bovine hydroxyapatite bioceramic
Authors: de Azevedo‐Silva Lucas José , Ferrairo Brunna Mota , Pires Luara Aline , Padovini David Santos Souza , Dias Leonardo Francisco Gonçalves , Erbereli Rogério , Fortulan Carlos Alberto , Lisboa‐Filho Paulo Noronha , Rubo José Henrique , Borges Ana Flávia Sanches 
Published: March 2022

AbstractThis study aimed to produce and characterize the microstructure and mechanical properties of dense polycrystalline bovine hydroxyapatite (DPBHA) bioceramics with 5% and 8% of TiO2 nanoparticles after final synthetization for future use in dental implants. Structural characterization was obtained from analyzes by Fourier transform infrared spectroscopy, X‐ray diffraction, scanning electron microscope, energy dispersive spectroscopy, and relative density and apparent porosity. The mechanical characterization was performed by measuring the fracture toughness after three‐point flexural strength (FS) test. The microstructural characterization results showed no secondary phase formation and nonhomogeneous nanoparticle dispersion in HA matrix. DPBHA/Np8% (2.9 ± 0.09 g/cm3) exhibited significantly greater density than DPBHA (2.7 ± 0.03 g/cm3) (p = 0.011) and DPBHA/Np5% (2.7 ± 0.05 g/cm3) (p = 0.041). DPBHA (0.9%) had the smallest porosity followed by DPBHA/Np8% (3.4%). DPBHA/Np5% (4.5%) exhibited the greatest proportion of pores. Pure HA (51.7 ± 10.3 MPa) and DPBHA/Np8% (47.4 ± 6.4 MPa) had significant greater FS (p < 0.001) than DPBHA/Np5% (28.8 ± 3.1 MPa). DPBHA (0.43 ± 0.01 MPa m1/2) and DPBHA/Np8% (0.40 ± 0.06 MPa m1/2) presented greater KIc than DPBHA/Np5% (0.23 ± 0.02 MPa m1/2) (p < 0.003; p < 0.007). In conclusion, 8% TiO2 nanoparticle addition to this synthesis would be a promising HA blend, as mechanical properties were similar, and the relative density/apparent porosity showed superior results than those of the DPBHA.
Solvent‐Free Thermal Synthesis of Extra‐Large‐Pore Aluminophosphate Zeotype via Self‐Assembly of Double‐Four‐Ring Unit
Authors: Huang Pengfei , Wei Ying , Hou Xiaozhe , Yao Zhenjiang , Li Haojie , Liang Yan , Jia Jingbo , Zhang Ling , Zhang Runduo 
Published: March 2022

AbstractThe use of Ge as framework atom to direct the formation of double‐four‐ring (d4r) unit is an effective way to prepare zeolite with extra‐large pores, which however also brings about serious problems with regard to production cost and structure stability for their practical application. A new solvent‐free thermal synthesis strategy is presented here for facile preparation and molecular‐level mechanism study of extra‐large‐pore aluminophosphate zeotype DNL‐1 with ‐CLO structure. For the first time, the formation of intermediate d4r in the induction period was successfully confirmed, and was correlated with the synthesis condition of low water content and quaternary ammonium template with suitable alkyl chain length. The self‐assembly pathway via d4r to form lta, afterwards clo and super cages was further revealed. This work shed light on the rational synthesis of Ge‐free extra‐large‐pore zeotypes based on d4r route.
Carbon‐coated Vanadium Oxide Nanoflowers with K+ Ions Pre‐embedment as a High‐rate Cathode for Zinc‐Ion Batteries
Authors: Zhou Min , Ma Jiajun , Yang Wensheng , Lu Shengshang , Tao Benfu , Qiu Liren , Wang Xinhai , Xie Quan , Ruan Yunjun 
Published: March 2022

AbstractRecently, aqueous zinc‐ion batteries have become a promising candidate for energy storage devices due to their low cost, high capacity, and environmental friendliness. However, the low electrical conductivity and irreversible Zn2+ intercalation/extraction of cathode materials limit the rate performance and cycling stability of Zn‐ion batteries. Herein, carbon‐coated V2O5 nanoflowers with K+ pre‐embedment (KVO‐C) were synthesized by hydrothermal and high‐temperature annealing methods, showing enhanced electrical conductivity and crystallinity. Assembled with Zn anode and 2 M Zn(CF3SO3)2 electrolyte, the optimized KVO‐C3 battery achieves a high specific capacity of 389.2 mAh g−1 at a current density of 0.1 A g−1 and retains 85% even with a 50‐fold increase in current density and cycling back to 0.1 A g−1. KVO‐C3 also shows excellent capacity retention of 77% and coulomb efficiency of nearly 100% after 2000 cycles and delivers a high energy density of 209 Wh kg−1 at a power density of 3500 W kg−1.
Genome‐wide association mapping of agronomic traits and grain characteristics in spring wheat under conventional and organic management systems
Authors: Semagn Kassa , Iqbal Muhammad , N'Diaye Amidou , Pozniak Curtis J. , Ciechanowska Izabela , Barbu Steliana‐Paula , Spaner Dean 
Published: March 2022

AbstractPrevious genome‐wide association studies in Canadian spring wheat (Triticum aestivum L.) cultivars were based on consensus linkage maps of small population sizes. Here, we used a panel of 192 spring wheat cultivars widely used in western Canada to (a) explore the allelic variation and effects of six known genes and (b) identify genomic regions associated with eight agronomic traits and grain characteristics using the International Wheat Genome Sequencing Consortium (IWGSC) RefSeq v2.0 map. The panel was evaluated for heading, maturity, plant height, lodging, grain yield, grain protein content, test weight, and kernel weight under four conventionally (high N) and three organically (low N) managed environments and genotyped with the wheat 90K single‐nucleotide polymorphism (SNP) array of which 23,342 SNPs were polymorphic. Using gene‐specific functional markers, the proportion of homozygous genotypes with favorable alleles was low for Fhb1 (7–8%), Rht‐D1 (14%), and Rht‐B1 (18%); moderate for Lr34/Yr18 (28–39%); and high for Glu‐A1 (78%) and Glu‐D1 (85%). We identified a total of 172 SNPs located at 94 genomic regions across 19 chromosomes of which 82 regions were associated with a single trait and 12 regions coincided with two to three traits. Twenty‐seven of the 94 regions (28%) were common between the conventional and organic managements systems; the remaining were management specific. Two of the identified regions on chromosome 5A (586.5–588.6 Mb) and 5B (575.8 Mb) coincided with the vernalization response Vrn‐A1 and Vrn‐B1 genes, respectively. The IWGSC RefSeq v2.0 physical positions presented here would serve as the basis for easily comparing independent discovery studies in the future.
Human endogenous retroviruses in viral disease and therapy
Authors: Li Yian , Fan Tianjiao , Cui Jie 
Published: March 2022

AbstractAs retained sequences of ancient retroviruses, human endogenous retroviruses (HERVs) are widespread in the human genome. Although most HERVs have been inert throughout evolution, several HERVs are still functional and involved in various diseases, such as autoimmune diseases, cancer, neurological diseases and viral infection. Hence, certain types of therapies targeting HERVs or utilizing HERV tools have been developed. Here, we summarize recent findings on the role of HERVs in viral infection, including HERV dysregulation in different kinds of viral infections and the potential mechanisms of HERV‐mediated antiviral immunity. In addition, we provide an overview of HERV‐related therapies that directly target HERVs or are indirectly based on HERVs to improve the efficacy of vaccines and drugs.
Single carrier variable rate scheme and modified carrier allocation over a wireless channel with carrier frequency offset
Authors: Khan Abdul Rauf , Kumar Preetam 
Published: March 2022

SummaryCyclic Prefix Orthogonal Frequency Division Multiplexing (CP‐OFDM) is the backbone for the 5G, Internet of Things (IoT), and future generation wireless networks. However, OFDM is less localized in the frequency domain, and that's why more sensitive to carrier frequency offset (CFO). In this paper, different multicarrier variable rate schemes are evaluated in the presence of CFO. Additionally, variable rate schemes based on group orthogonal‐orthogonal frequency division multiple access (GO‐OFDMA) are discussed, and the effect of changing carrier allocation is examined. Different allocation schemes along with different variable rate schemes are verified in the presence of the CFO. Further for Up‐link variable rate application, single‐carrier scenario for the variable rate is proposed in this paper, and bit error rate (BER) performance is evaluated and compared with the variable rate GO‐OFDMA.
Prevalence, management, and outcomes of haemorrhagic events in left ventricular assist device recipients
Authors: Pourtau Laetitia , Beneyto Maxime , Porterie Jean , Roncalli Jerome , Massot Montse , Biendel Caroline , Fournier Pauline , Itier Romain , Galinier Michel , Lairez Olivier , Delmas Clement 
Published: March 2022

AbstractAimsLeft ventricular assist devices (LVADs) have reduced the mortality of patients with advanced heart failure both as bridge‐to‐transplant and as destination therapy. However, LVADs are associated with various complications, including bleedings, which affect the prognosis. The aim of the study was to explore the prevalence, management, and outcomes of haemorrhagic adverse events in LVAD recipients.Methods and resultsWe conducted a retrospective, single‐centre, cohort study including all patients who received an LVAD from January 2008 to December 2019 in our tertiary centre (Rangueil University Hospital, Toulouse, France). Bleeding events, death, and heart transplantation were collected from electronic medical files. Eighty‐eight patients were included, and 43 (49%) presented at least one bleeding event. Gastrointestinal (GI) bleeding was the most frequent (n = 21, 24%), followed by epistaxis (n = 12, 14%) and intracranial haemorrhage (n = 9, 10%). Bleeding events were associated with increased mortality [hazard ratio (HR) 3.8, 95% confidence interval (CI) 1.5–9.3, P < 0.01], particularly in case of intracranial haemorrhage (HR 14.6, 95% CI 4.2–51.1, P < 0.0001). GI bleedings were associated with a trend towards increased mortality (HR 3.0, 95% CI 0.9–9.3, P = 0.05). Each bleeding episode multiplied the risk of death by 1.8 (95% CI 1.2–2.7, P < 0.01). Finally, only early bleedings (<9 months post‐implantation) had an impact on mortality (HR 4.2, 95% CI 1.6–11.1, P < 0.01). Therapeutic management was mainly based on temporary interruption of anticoagulation and permanent interruption of antiplatelet therapy. Invasive management was rarely performed.ConclusionsHaemorrhagic events in LVAD recipients are frequent and associated with increased mortality. GI bleedings are the most frequent, and intracranial haemorrhages the most associated with mortality. Management remains empirical requiring more research.
Utility of left atrial and ventricular strain for diagnosis of transthyretin amyloid cardiomyopathy in aortic stenosis
Authors: Oike Fumi , Usuku Hiroki , Yamamoto Eiichiro , Marume Kyohei , Takashio Seiji , Ishii Masanobu , Tabata Noriaki , Fujisue Koichiro , Yamanaga Kenshi , Sueta Daisuke , Hanatani Shinsuke , Arima Yuichiro , Araki Satoshi , Oda Seitaro , Kawano Hiroaki , Soejima Hirofumi , Matsushita Kenichi , Ueda Mitsuharu , Fukui Toshihiro , Tsujita Kenichi 
Published: March 2022

AbstractAimsTo clarify the usefulness of left atrial (LA) function and left ventricular (LV) function obtained by two‐dimensional (2D) speckle tracking echocardiography to diagnose concomitant transthyretin amyloid cardiomyopathy (ATTR‐CM) in patients with aortic stenosis (AS).Methods and resultsWe analysed 72 consecutive patients with moderate to severe AS who underwent 99mTc‐pyrophosphate (PYP) scintigraphy at Kumamoto University Hospital from January 2012 to September 2020. We divided these 72 patients into 2 groups based on their 99mTc‐PYP scintigraphy positivity or negativity. Among 72 patients, 16 patients (22%) were positive, and 56 patients (78%) were negative for 99mTc‐PYP scintigraphy. In clinical baseline characteristics, natural logarithm troponin T was significantly higher in the 99mTc‐PYP scintigraphy‐positive than scintigraphy‐negative group (−2.9 ± 0.5 vs. −3.5 ± 0.8 ng/mL, P < 0.05). In conventional echocardiography, the severity of AS was not significantly different between these two groups. In 2D speckle tracking echocardiography, the relative apical longitudinal strain (LS) index (RapLSI) [apical LS/ (basal LS + mid LS)] was significantly higher (1.09 ± 0.49 vs. 0.78 ± 0.23, P < 0.05) and the peak longitudinal strain rate (LSR) in LA was significantly lower in the 99mTc‐PYP scintigraphy‐positive than scintigraphy‐negative group (0.36 ± 0.14 vs. 0.55 ± 0.20 s−1, P < 0.05). Multivariable logistic analysis revealed the peak LSR in LA and RapLSI were significantly associated with 99mTc‐PYP scintigraphy positivity. Receiver operating characteristic analysis showed that the area under the curve (AUC) of the peak LSR in LA for 99mTc‐PYP scintigraphy positivity was 0.79 and that the best cut‐off value of the peak LSR in LA was 0.47 s−1 (sensitivity: 78.6% and specificity: 72.3%). The AUC of RapLSI for 99mTc‐PYP scintigraphy positivity was 0.69, and the cut‐off value of RapLSI was decided as 1.00 (sensitivity: 43.8% and specificity: 87.5%) according to the previous report. The 99mTc‐PYP scintigraphy positivity in patients with RapLSI ≥ 1.0 and the peak LSR in LA ≤ 0.47 s−1 was 83.3% (5/6), and the 99mTc‐PYP scintigraphy negativity in patients with RapLSI < 1.0 and the peak LSR in LA > 0.47 s−1 was 96.6% (28/29).ConclusionsLeft atrial and LV strain analysis were significantly associated with 99mTc‐PYP scintigraphy positivity in ATTR‐CM patients with moderate to severe AS. The combination of the peak LSR in LA and RapLSI might be a useful predictor of the presence of ATTR‐CM in patients with moderate to severe AS.
Comparative of MIL101(Cr) and nano‐MIL101(Cr) Electrode as an Electrochemical Hydrogen Peroxide Sensor
Authors: Salman Fırat , Kazıcı Hilal Çelik , Gülcan Mehmet 
Published: March 2022

AbstractHerein, an electrochemical sensor for the detection of H2O2 based on nafion glassy carbon electrode modified with MIL101(Cr) and nano‐MIL101(Cr) are developed and its electrochemical characterizations analyzed by CV and CA. In comparison with the NGCE, MIL101/NGCE and nano‐MIL101/NGCE, the nano‐MIL101/NGCE showed a sharp redox peak specific to H2O2 was obtained in the phosphate‐calibrated solution. nano‐MIL101/NGCE exhibited good linear response in terms of the relationship between peak currents and concentrations as from 0 to 650 μM (R2=0.99), with a low limit of detection 3.8 μM, high sensitivity 986 μA mM−1 cm−2 and nano‐MIL101/NGCE exhibited ideal repeatability, reproducibility, stability and the interference‐free perception of H2O2.