bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acceptability and Feasibility of Wearable Transdermal Alcohol Sensors: Systematic Review
Authors: Brobbin Eileen , Deluca Paolo , Hemrage Sofia , Drummond Colin 
Published: November 2022

Background
Transdermal alcohol sensors (TASs) have the potential to be used to monitor alcohol consumption objectively and continuously. These devices can provide real-time feedback to the user, researcher, or health professional and measure alcohol consumption and peaks of use, thereby addressing some of the limitations of the current methods, including breathalyzers and self-reports.

Objective
This systematic review aims to evaluate the acceptability and feasibility of the currently available TAS devices.

Methods
A systematic search was conducted in CINAHL, EMBASE, Google Scholar, MEDLINE, PsycINFO, PubMed, and Scopus bibliographic databases in February 2021. Two members of our study team independently screened studies for inclusion, extracted data, and assessed the risk of bias. The study’s methodological quality was appraised using the Mixed Methods Appraisal Tool. The primary outcome was TAS acceptability. The secondary outcome was feasibility. The data are presented as a narrative synthesis.

Results
We identified and analyzed 22 studies. Study designs included laboratory- and ambulatory-based studies, mixed designs, randomized controlled trials, and focus groups, and the length the device was worn ranged from days to weeks. Although views on TASs were generally positive with high compliance, some factors were indicated as potential barriers and there are suggestions to overcome these.

Conclusions
There is a lack of research investigating the acceptability and feasibility of TAS devices as a tool to monitor alcohol consumption in clinical and nonclinical populations. Although preliminary evidence suggests their potential in short-term laboratory-based studies with volunteers, more research is needed to establish long-term daily use with other populations, specifically, in the clinical and the criminal justice system.

Trial Registration
PROSPERO CRD42021231027; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=231027
Continued Use of Contact-Tracing Apps in the United States and the United Kingdom: Insights From a Comparative Study Through the Lens of the Health Belief Model
Authors: Zhang Zhan , Vaghefi Isaac 
Published: November 2022

Background
To contain the spread of SARS-CoV-2, contact-tracing (CT) mobile apps were developed and deployed to identify and notify individuals who have exposure to the virus. However, the effectiveness of these apps depends not only on their adoption by the general population but also on their continued use in the long term. Limited research has investigated the facilitators of and barriers to the continued use of CT apps.

Objective
In this study, we aimed to examine factors influencing the continued use intentions of CT apps based on the health belief model. In addition, we investigated the differences between users and nonusers and between the US and UK populations.

Methods
We administered a survey in the United States and the United Kingdom. Respondents included individuals who had previously used CT technologies and those without experience. We used the structural equation modeling technique to validate the proposed research model and hypotheses.

Results
Analysis of data collected from 362 individuals showed that perceived benefits, self-efficacy, perceived severity, perceived susceptibility, and cues to action positively predicted the continued use intentions of CT apps, while perceived barriers could reduce them. We observed few differences between the US and UK groups; the only exception was the effect of COVID-19 threat susceptibility, which was significant for the UK group but not for the US group. Finally, we found that the only significant difference between users and nonusers was related to perceived barriers, which may not influence nonusers’ continued use intentions but significantly reduce experienced users’ intentions.

Conclusions
Our findings have implications for technological design and policy. These insights can potentially help governments, technology companies, and media outlets to create strategies and policies to promote app adoption for new users and sustain continued use for existing users in the long run.
Exploring the Cross-cultural Acceptability of Digital Tools for Pain Self-reporting: Qualitative Study
Authors: Ali Syed Mustafa , Lee Rebecca R , McBeth John , James Ben , McAlister Sean , Chiarotto Alessandro , Dixon William G , van der Veer Sabine N 
Published: November 2022

Background
Culture and ethnicity influence how people communicate about their pain. This makes it challenging to develop pain self-report tools that are acceptable across ethnic groups.

Objective
We aimed to inform the development of cross-culturally acceptable digital pain self-report tools by better understanding the similarities and differences between ethnic groups in pain experiences and self-reporting needs.

Methods
Three web-based workshops consisting of a focus group and a user requirement exercise with people who self-identified as being of Black African (n=6), South Asian (n=10), or White British (n=7) ethnicity were conducted.

Results
Across ethnic groups, participants shared similar lived experiences and challenges in communicating their pain to health care professionals. However, there were differences in beliefs about the causes of pain, attitudes toward pain medication, and experiences of how stigma and gender norms influenced pain-reporting behavior. Despite these differences, they agreed on important aspects for pain self-report, but participants from non-White backgrounds had additional language requirements such as culturally appropriate pain terminologies to reduce self-reporting barriers.

Conclusions
To improve the cross-cultural acceptability and equity of digital pain self-report tools, future developments should address the differences among ethnic groups on pain perceptions and beliefs, factors influencing pain reporting behavior, and language requirements.
Optimasi bubuk bunga telang, enzim transglutaminase, dan bread improver untuk meningkatkan fungsionalitas dan kualitas roti manis [Optimizing the butterfly pea powder, transglutaminase enzyme, and bread improver to improve the functionality and quality of sweet bread]
Authors: Wulandari Endah , Ishmayana Safri , Marta Herlina , Fadhlillah Muhammad , Isnaeni Nurisa Fadillah 
Published: November 2022

Sweet bread with moderate functional properties can be enhanced with tertiary function by adding telang flower, a natural ingredient rich in antioxidants, natural blue in color derived from anthocyanins. In addition, bread volume enhancers, such as transglutaminase enzymes and bread improvers are also needed to improve the quality of bread. The purpose of this study was to determine the optimum formulation of telang flower sweet bread using Response Surface Method (RSM)-Central Composite Design (CCD) with telang flower powder (2-6%), transglutaminase enzyme (0.027-0.083 U/g protein), and breading agent (3-9 U/g flour) as an independent variable, and produces a response in the form of specific volume and antioxidant activity. The optimum formula was obtained with a combination of 4.71% telang flower powder formula, transglutaminase enzyme 0.055 U/g flour protein, and 5.23 U/g flour bread improver which resulted in a specific volume of 3.15 ± 0.05 cm3/g and activity antioxidant amounted to 388.372 ± 13.11%. The characteristics of the optimum bread had firmness values of 629.77±39.23 g.f, springiness 42.14±0.87%, sweet bread crumbs were dark blue, but the butterfly pea flower sweet bread's quality was not as well accepted as the control sweet bread with the exception of how the bread feels when bitten.
Pengaruh penambahan kacang merah dan ketan hitam terhadap sifat sensori dan gizi minuman berbasis jamur tiram dan wijen hitam[[The effect of the addition of red beans and black glutinous rice on the sensory and nutritional properties of oyster mushroom and black sesame-based drinks]
Authors: Yustiana Anisa , Nurdjanah Siti , Nurdin Samsu Udayana , Murhadi Murhadi , Sartika Dewi 
Published: November 2022

One example of a plant-based product is mixed grain-based milk. Mixing various types of grains such as red beans, black glutinous rice, black sesame, and oyster mushrooms is expected to complement the nutritional content and improve the sensory properties of the final product. This research was aimed to determine the effect of the proportion of red beans and black glutinous rice on the mixture of grains and oyster mushrooms on the sensory quality of mixed grain milk and find the best proportion of red beans and black glutinous rice in the mixture of grains and oyster mushrooms that produce plant-based milk with the best sensory quality. This research was conducted in a Randomized Complete Block Design (RCBD) with a single treatment in the form of a comparison of red beans, and black glutinous rice consisting of 6 formulations with 4 replications. Parameters observed were sensory properties (aroma, taste and aftertaste). The sample with the best sensory properties was further analyzed proximate content and amino acid profile. The results showed that addition of red beans and black glutinous rice to plant-based milk on oyster mushrooms and black sesame affected sensory qualities (taste, aroma, and aftertaste). The best treatment was the proportion of 60:30 with a taste score of 7.49 (tends to be savory sweet), an aroma score of 7.73 (tends to be pleasant), an aftertaste score of 7.11 (tends to be normal); a moisture content of 85.29%; a protein content of 1.72%; fat content 0.88%; carbohydrates 11.77%; ash 0.34%; and 61.88 kcal of calories per 100 mL.
Third-order critical family therapy: rethinking psychopathology and psychotherapy
Authors: Medina Centeno Raúl 
Published: November 2022

Background: The focus of third-order critical family therapy is to raise awareness of the systems of systems – structural, socioeconomic and cultural contexts– that organize lifestyles that interfere with health. This clinical proposal integrates systemic wisdom with social theories, and in particular delves into a sociocultural theory of the human mind, power and emotions, a set of concepts from which indignant love, solidarity dialogue, critical honesty emerge, as the axes from which clinical work is woven. The ultimate goal is for the family to restore critical solidarity dialogue and empower themselves in their well-being. Method: Our study is narrative. Conclusion: This clinical proposal leads to re-thinking psychopathology not as an individual or biological problem, but as a resistance to those contexts of belonging that excludes and mistreats, and therefore to diagnosis as an active organized social framework. And on the other hand, also to psychotherapy and psychotherapist who must always be critically attentive to explain the androcentrist, classist and Eurocentric privileges of clinical theory and practice, to become health professionals with a social, human, political and ethical perspective.
Cows enrolled in a pilot randomized clinical trial evaluating pegbovigrastim administered to dairy cows at dry-off had reduced incidence of intramammary infection
Authors: de Campos Juliana Leite , Strickland Jaimie M. , Gandy Jeff C. , Robison Cara I. , Ruegg Pamela L. 
Published: November 2022

Abstract

OBJECTIVE
The objective of this pilot study was to determine if an alternative dosing schedule of pegbovigrastim (PEG; Imrestor; Elanco Animal Health) affects mammary gland health, rear udder width, or milk production of healthy dairy cows.

ANIMALS
20 pregnant late-lactation Holstein cows in November 2019 through April 2020.

PROCEDURES
Cows were randomly assigned to receive subcutaneous injections with either 15 mg of PEG (PEG group; n = 10) or a sham injection with saline (0.9% NaCl) solution (control group; 10) administered 7 days before dry-off and at dry-off. Quarter milk samples were collected for bacterial culture and somatic cells before and after dry-off and after calving. Mammary gland width was assessed before and after dry-off. Daily milk yields were evaluated after calving.

RESULTS
The incidence of intramammary infection was 5 times greater for quarters of cows in the control group than for quarters of cows that received PEG. The effect of treatment on somatic cell count was not significant, but the effects of period and a treatment-by-period interaction were identified. Treatment did not significantly affect milk production in the subsequent lactation, but the effects of period and an interaction of treatment by period were identified. Rear udder width after dry-off was not significantly affected by treatment, but an effect of period was identified.

CLINICAL RELEVANCE
In this pilot study, cows treated with PEG using an alternative dosing schedule had reduced incidence of intramammary infection and an interaction of treatment by sampling period was observed for milk yield. These results suggest that further studies with larger numbers of cows are warranted.
Clinical and laboratory characteristics of haemophilus influenza type b Infection with central nervous system Involvement in young children
Authors: Sitkina E. L. , Antonova T. V. , Ivanova R. A. , Lioznov D. A. 
Published: November 2022

Introduction. Invasive Haemophilus influenza type b (Hib) infection often manifests as severe and complicated forms of purulent meningitis in children from birth to 6 years of age. Hib meningitis is the most commonly diagnosed invasive form, with a severe course. There is no generally accepted clinical classification of Hib infection. Along with meningitis, the infection is often manifested with purulent inflammatory foci of different localization.The objective was to characterize the course of purulent Hib meningitis, including in combination with purulent foci, in young children.Methods and materials. We analyzed 45 case histories of children (under the age of 3 years) who had an invasive Haemophilus infection with purulent meningitis. Hib meningitis (Group-1) was diagnosed in 17 patients and meningitis in combination with specific purulent foci was diagnosed in 28 patients (Group-2). The diagnosis in all patients was confirmed bacteriologically or serologically (Latex Agglutination Test).Results. The combination of meningitis with purulent foci of Hib infection was characterized by late hospitalization (36 %), longer recovery of cerebrospinal fluid, longer duration of the disease, and the prevalence of severe and complicated disease, and often required surgical treatment (46.4 %). A burdened premorbid background is traditionally considered a condition for the development of invasive Hib infection. According to our data, only 40 % of children had a burdened premorbid background, which is confirmed by clinical cases.Conclusion. Since Hib infection in young children is often combined with meningitis with purulent foci, is characterized by a severe and complicated course, and often requires surgical treatment, it is advisable to consider this form of infection separately.
Dopamine receptor DRD1 expression (mRNA, protein level) in peripheral blood lymphocytes and prognosis of antipsychotic therapy
Authors: Zabotina A. M. , Zhuravlev A. S. , Grunina M. N. , Nasyrova R. F. , Volkova E. V. , Tyurin A. A. , Limankin O. V. , Otmakhov A. P. , Krupitsky E. M. , Neznanov N. G. , Taraskina A. E. 
Published: November 2022

Introduction. There is a problem in predicting the efficacy and safety of antipsychotic therapy. Dopamine receptor D1 is one of the targets of antipsychotics. Peripheral blood lymphocytes (PBL) are the research object of neurotransmission receptors.The objective was to study DRD1 gene expression (mRNA, protein level) in PBL as a possible biomarker of olanzapine and haloperidol therapy prognosis.Methods and Materials. Sample: 106 patients diagnosed with schizophrenic spectrum disorder. Study design: prospective longitudinal follow-up with drug administration by randomization. Assessment of mental status and development of Parkinsonism: Positive and Negative Syndrome Scale (PANSS) and Simpson-Agnus Scale (SAS), respectively. PBL was study material. DRD1 mRNA level was determined by real-time PCR. DRD1 protein concentration in PBL was measured by enzyme immunoassay.Results. Haloperidol (but not olanzapine) treatment for 28 days, leads to DRD1 protein concentration decrease in PBL in a manner dependent on its initial level. DRD1 mRNA level in PBL remained unchanged during the treatment. Patients with effective therapy by olanzapine had lower DRD1 mRNA levels. Side effects of the therapy (Parkinsonism, weight gain) were not associated with studied DRD1 parameters.Conclusions. Haloperidol treatment leads to a decrease of DRD1 protein concentration in PBL, which depends on the initial protein level. Effective olanzapine therapy is associated with reduced DRD1 mRNA level in PBL before the treatment.
Ventral posteromedial nucleus of the thalamus as a neuroanatomical target for the anticephalalgic action of valproic acid and metamizole
Authors: Sokolov A. Yu. , Lyubashina O. A. 
Published: November 2022

Introduction. Valproic acid and metamizole are widely used in the treatment of primary headaches. However, despite the drugs’ proven clinical efficacy, the neurophysiological mechanisms underlying their therapeutic action are poorly understood. The ventral posteromedial nucleus of the thalamus (VPM) serves as the highest suprasegmental relay center for transmitting ascending nociceptive information from the cranial structures to the cerebral cortex and is considered as a potential neuroanatomical target for anticephalalgic drugs.The objective of the study was to evaluate the action of valproate and metamizole on the excitability of the VPM thalamic neurons.Methods and materials. In acute controlled experiments on anesthetized rats (n=31), we studied the action of cumulative dosing (three fixed dose injections every 30 minutes) of intravenously administered valproate (n=8, 100 mg/kg x 3) or metamizole (n=16,150 mg/kg · 3) on extracellularly recorded background and dura mater electrical stimulation-evoked activities of the convergent VPM neurons. Results. In all experiments, intravenous valproate significantly inhibited both background activity of the VPM neurons and their responses to dural electrostimulation. Metamizole had a similar action in more than half of the cases, whereas 44 % of the examined thalamic cells (7 out of 16) did not react to its infusion.Conclusion. One of the main neurophysiological mechanisms underlying anticephalalgic action of valproic acid and metamizole may be inhibition of the nociceptive transmission at the thalamic level due to the drugs-induced suppression of the meningeal-sensitive VPM neurons excitability.
Epidemiology and results of the first line therapy for HIV-related Hodgkin lymphoma
Authors: Chekalov A. M. , Popova M. O. , Tsygankov I. V. , Rogacheva Yu. A. , Volkov N. P. , Lepik K. V. , Demchenkova M. V. , Schneider T. V. , Kopeikina Yu. V. , Medvedeva N. V. , Zyuzgin I. S. , Pavlyuchenko E. S. , Levanov A. N. , Myasnikov A. A. , Kariagina E. V. , Mikhailova N. B. , Baykov V. V. , Kulagin A. D. 
Published: November 2022

Introduction. The risk of developing Hodgkin lymphoma (HL) with HIV infection is higher than in the general population, and the course of the disease itself is more aggressive. Currently, there is no unified approach to the treatment of HIV-related HL, and data on its epidemiology in the Russian Federation are limited.The objective was to study epidemiological characteristics, the used therapeutic tactics and the results of treatment for HIV-related HL.Methods and materials. The multicenter retrospective study included 46 patients with HIV- related HL treated in 9 centers of the Russian Federation. Descriptive statistics methods were used, the analysis of overall survival (OS) and progression-free survival (PFS) was performed using the Kaplan–Meier method.Results. HIV-related HL is more often represented by an advanced stage, B-symptoms, and extranodal lesions. The ABVD regimen was used as the first-line therapy in 60 % for HIV-related HL. The overall response to therapy was 81.6 %, and the 2-year OS and PFS were 85 % and 49 %, respectively. Factors that worsened OS were CD4+˂266 cells/mcL and general somatic status ECOG≥2.
The Effect of Using Spaced Learning Repetition Method on Iraqi Islamic School Students' Achievement in English Language
Authors: Mustafa AL-Okiedy Omar Mahmood 
Published: November 2022

The current study aims to investigate the effect of using spaced learning repetition method on Iraqi Islamic school students' achievement in English language. The aim of the study is supposed to be achieved through verifying its hypothesis. The sample of the study consists of twenty EFL Islamic school students who are spread into both groups, the experimental groups and control .The experimental group has been taught the English reading comprehension(The Prophet of Allah unit seven and eight) by using spaced learning repetition method ,while the control group has been taught the same material by using their current method. A posttest has been applied and conducted to the both groups. The required data are collected and analysed statistically. The gained findings show that the mean scores of students' achievement of the experimental group in the posttest are better than that of the control group. This means that the investigated method has an efficient effect on Iraqi Islamic school learners' achievement language of English.
Exhibition activity of the Palekh lacquer miniature craft (1945-1989)
Authors: Lavrov Dmitrii Evgen'evich 
Published: November 2022

The study is a continuation of the article "Exhibition activity of the Palekh lacquer miniature craft (1923-1939)", published in the scientific journal "Man and Culture". The subject of the proposed work is an analysis of the exhibition activity of the Palekh lacquer craft in the post-war period, limited to the second half of the 1940s and the end of the 1980s. The purpose of the article is to use historical, typological and structural research methods, as well as a historical and systematic approach, to show the specifics of this period in the history of the exhibition activity of the Palekh craft. Emphasizing the continuity of the exhibition activities of the 1940s - 1980s with the pre–war period, the author at the same time points out the new features that appear in the exhibition practices of the craft in the post-war period. The scientific novelty of the research consists in the fact that the author analyzes the most important art shows of the Soviet Union, where the products of the Palekh lacquer miniature were exhibited in the 1940s – 1980s. The article pays special attention to the activities of the State Museum of Palekh Art, which after its opening in 1935 became an important exhibition center for lacquer craft products, personal, retrospective, thematic and traveling exhibitions are considered. The main conclusion of the article is the substantiation of the importance of the considered topic for understanding the public recognition and fame that the Palekh lacquer miniature craft acquired in the late Soviet period, as well as in the post-Soviet period.