bluuebunny/crossref_metadata_2025_split huggingface dataset:
Designing a Hypothetical Model of Fourfold Vedic Music Therapy (FVMT) from the Aśvamedhic Uttaramandrā-Gāthā
Authors: Gangopadhyay Abirlal , Prasad J. S. R. 
Published: October 2022

Music, as a therapy, is more than often effectively administered across the globe. Interestingly, the roots of the music therapy are found in the _Uttaramandrā-gāna_ or _Gāthā-gāna_ which is a part of the _Aśvamedha_ rite. In order to perform the _Aśvamedha_ rite, the king needs to transfer the authority to a priest for a year. Without his sceptre or the rod of authority, he might undergo psychological stress. During this period, two musicians would pour out self-composed strains of valour to the accompaniment of an arched harp. This would keep the king motivated and confident until the period is over. From that perspective, it can be postulated that _Uttaramandrā_ is the basis of Indian music therapy. Since this process helps to evoke positive emotions, we have tried to develop an outline of a fourfold therapeutic model of Indian music therapy for this modern era with a connection to the Vedic lineage with reference to the _rasa_ theory of Indian aesthetic, Ayurvedic principles, and ancient accounts of Indian musicology.
Elderly social connectedness through social media platforms: a scoping review
Authors: Oti-Boadi Mabel , Dei Daniel 
Published: October 2022

Social connectedness is a fundamental human right and plays a significant role in the well-being of the elderly. Lack of connectedness is related to higher rates of mortality and morbidity. The emergence of COVID-19 and its associated social/physical distancing has brought the importance of social connectedness for human health and well-being, especially for the elderly, into a sharp focus. Globally, the adoption of social media platforms to create connectedness has been increasing across all age groups, including older populations. However, not all elderly can use these social media platforms to connect with their significant others. Using a scoping review, the study highlights the concerns for social connectedness among the elderly in an era where the COVID-19 pandemic continues to wear away all elements of in-person social connectedness. The study describes emerging concerns as the elderly attempt to establish and sustain the much-needed social connectedness through social media platforms. The study suggests functional approaches to dealing with these concerns to improve the well-being of the elderly.
Biology and Management of Oxalis (Oxalis stricta) in Ornamental Crop Production
Authors: Lollar Matthew , Marble Chris 
Published: October 2022

Oxalis grows throughout the year in Florida. It can be found growing in sidewalk cracks, alongside trails, in lawns, flower beds, cultivated fields, and in container nursery stock. In greenhouse studies, oxalis populations have been shown to negatively impact the growth rates of ornamental crops. This 6-page fact sheet was written by Matt Lollar and Chris Marble, and published by the UF Department of Environmental Horticulture, February 2015. (Photo: Chris Marble)
ENH1253/EP514: Biology and Management of Oxalis (Oxalis stricta) in Ornamental Crop Production (ufl.edu)
Positive Discipline: Behavioral Management Skills for Parents and Teachers Part 2—General Approaches to Managing Behavior
Authors: Harris Victor , Fung Whitney , Ellis Sarah , Schmeer Alison 
Published: October 2022

When a child is locked in the bathroomWith water runningAnd he says he is doing nothingBut the dog is barking,Call 911.–Erma Bombeck
Research indicates that there must be at least an 8-to-1 positive-to-negative interaction ratio for parents and teachers to have a positive relationship with their children and students. Put simply, both verbal and non-verbal communication needs to be generally positive. Learning how to steer a child or a student toward managing his or her own behavior in healthy ways requires both knowledge and skills that make it easy to have positive interactions and behavior change. This 6-page fact sheet will help you identify specific approaches to successfully managing appropriate and inappropriate behavior at home and in the classroom. It outlines four principles of behavior management, and describes several strategies before providing a practice activity. Written by Victor Harris, Whitney Fung, Sarah Ellis, and Alison Schmeer, and published by the UF Department of Family, Youth and Community Sciences, July 2015. (Photo Credit: Thinkstock.com/Jupiterimages/Creatas Images)
FCS3329/FY1459: Positive Discipline: Behavioral Management Skills for Parents and Teachers—Part 2: General Approaches to Managing Behavior (ufl.edu)
Positive Discipline: Behavioral Management Skills for Parents and Teachers Part 3—Fostering the Parent–Child and Teacher–Student Relationship to Build Responsibility
Authors: Harris Victor , Fung Whitney , Ellis Sarah , Schmeer Alison 
Published: October 2022

Tell me and I forget,Teach me and I may remember,Involve me and I learn.
The general goal of healthy parenting and teaching is to produce children and students who can think critically, make good decisions, and become independent, accountable, responsible, and contributing members of society. Part 3 of this Positive Discipline: Behavioral Management Skills for Parents and Teachers series covers tips and strategies to help parents and teachers build critical thinking and positive behavioral skills in children. Several of these strategies that can help parents and teachers achieve these goals through “love and logic” are discussed in this 6-page fact sheet written by Victor Harris, Whitney Fung, Sarah Ellis, and Alison Schmeer, and published by the UF Department of Family Youth and Community Sciences, July 2015. (Photo Credit: Thinkstock.com/iStock/natasaadzic)
FCS3330/FY1460: Positive Discipline: Behavioral Management Skills for Parents and Teachers—Part 3: Fostering the Parent–Child and Teacher–Student Relationship to Build Responsibility (ufl.edu)
Techniques for Melon Grafting
Authors: Guan Wenjing , Zhao Xin 
Published: October 2022

Grafting as a cultural practice for controlling soilborne diseases and improving abiotic stress tolerance has been widely used in vegetable production in many areas of Asia and Europe. Interest in vegetable grafting has been growing in the United States in recent years, as well. Cost, along with the desire to customize scion cultivars and the need to produce organic transplants, has led many small and organic growers to choose to graft plants by themselves. To help growers who are interested in grafting melon plants achieve a high graft survival rate, this 5-page fact sheet introduces commonly used grafting techniques and their application in specific circumstances. Written by Wenjing Guan and Xin Zhao, and published by the UF Department of Horticultural Sciences, December 2014.
HS1257/HS1257: Techniques for Melon Grafting (ufl.edu)
DEMONSTRATIVE REFERENCE ANALYSIS IN THE JAKARTA POST HEALTH NEWS OCTOBER 2020 EDITION
Authors: Shabrina Nadhilah Nur 
Published: October 2022

Demonstrative reference is required to conduct a well-written text. Because it performs a specific function, such as referring to items in the text or signal specificity, etc., it must be clear to avoid misinterpretation of the news and make it understandable to the readers. As a result, the purpose of this qualitative study was to look into the occurrence, function, and specific pattern of demonstrative references in the Jakarta Post health news October 2020 edition. Halliday and Hasan's theory of cohesive devices was used to conduct the study. There were XXX demonstrative references found in the 10 news of health topic October 2020 edition as the object of the study. The most demonstrative reference was used by news xxx, which had 368 items, while the least was used by news xxx, which only had 2 items. The specific pattern found in the news by using the types and functions of demonstrative reference is that the news conveys cautions, preventions, suggestions, expectations, and hopes for the reader to understand the current situation conveyed by the news and build a better world after the chaos brought by the virus.
Keywords: demonstrative reference, health news, The Jakarta Post
Covalent immobilization of VEGF on allogeneic bone through polydopamine coating to improve bone regeneration
Authors: Huang Jianhao , Lu Jingwei , Liu Ziying , Jin Jing , Xie Chunmei , Zheng Yang , Wang Zhen , Yu Lingfeng , Zhu Yan , Fan Gentao , Sun Guojing , Xu Zhihong , Zhou Guangxin 
Published: October 2022

Objective: Promoting bone regeneration and repairing in bone defects is of great significance in clinical work. Using a simple and effective surface treatment method to enhance the osteogenic ability of existing bone scaffold is a promising method. In this article, we study the application of catecholic amino acid 3,4-dihydroxyphenylalanine (DOPA) surface coating chelated with vascular endothelial growth factor (VEGF) on allogeneic bone.Method: Allogeneic bone is immersed in DOPA solution and DOPA form polydopamine (PDA) with good adhesion. Electron microscopy is used to characterize the surface characteristics of allogeneic bone. MC3T3-E1 cells were tested for biocompatibility and osteogenic signal expression. Finally, a 12-week rabbit bone defect model was established to evaluate bone regeneration capability.Results: We found that the surface microenvironment of DOPA bonded allogeneic bone was similar to the natural allogeneic bone. VEGF loaded allografts exhibited satisfying biocompatibility and promoted the expression of osteogenic related signals in vitro. The VEGF loaded allografts healed the bone defect after 12 weeks of implantation that continuous and intact bone cortex was observed.Conclusion: The PDA coating is a simple surface modification method and has mild properties and high adhesion. Meanwhile, the PDA coating can act on the surface modification of different materials. This study provides an efficient surface modification method for enhancing bone regeneration by PDA coating, which has a high potential for translational clinical applications.
Feasibility of bacterial-enzyme induced carbonate precipitation technology for stabilizing fine-grained slope soils
Authors: Gowthaman Sivakumar , Iki Takashi , Ichinohe Aoi , Nakashima Kazunori , Kawasaki Satoru 
Published: October 2022

Microbial Induced Carbonate Precipitation (MICP) has recently become a new technology for stabilizing the slope surface. The applicability of MICP, however, is limited in fine-grained soils due to the restrictions regarding the transportation of bacteria cells. The purpose of this study was to assess the feasibility of an alternative called Bacterial-Enzyme Induced Carbonate Precipitation (B-EICP) for stabilizing the fine-grained slope soils. Unlike the MICP strategy (involving whole-cells of bacteria), the proposed B-EICP utilizes bacterial urease to induce the bio-cement formation within soil. The whole-cell culture of Lysinibacillus xylanilyticus was subjected to cyclic sonication to extract the free urease suspension. The B-EICP treatment was performed to the columns prepared using two different soils obtained from representative expressway slopes. The cementation responses of the proposed B-EICP were compared with that of typical MICP method, especially from the following viewpoints, (i) adaptability to soil with high fine-grained content, (ii) conditions under which B-EICP can be effectively applied and (iii) cementation under low temperature. The results revealed that the extract solution had higher urease activity compared to original bacteria culture, and the activity remained more stable at low temperature conditions (15°C). The results further confirmed that B-EICP method is more suitable for stabilizing soils with large amount of fine particles. Comparing with MICP, the B-EICP resulted higher unconfined compressive strength (over 1200 kPa) and deeper cementation in the silty sand. Microscale analysis suggested that the B-EICP could induce smaller calcium carbonate crystals than that by MICP, but the number of crystals in B-EICP were significantly more, thus contributed to increased particle-particle cementation.
Research progress on the antiviral activities of natural products and their derivatives: Structure–activity relationships
Authors: Guo Yajing , Ma Anna , Wang Xinyan , Yang Chen , Chen Xi , Li Gen , Qiu Feng 
Published: October 2022

Viruses spread rapidly and are well-adapted to changing environmental events. They can infect the human body readily and trigger fatal diseases. A limited number of drugs are available for specific viral diseases, which can lead to non-efficacy against viral variants and drug resistance, so drugs with broad-spectrum antiviral activity are lacking. In recent years, a steady stream of new viral diseases has emerged, which has prompted development of new antiviral drugs. Natural products could be employed to develop new antiviral drugs because of their innovative structures and broad antiviral activities. This review summarizes the progress of natural products in antiviral research and their bright performance in drug resistance issues over the past 2 decades. Moreover, it fully discusses the effect of different structural types of natural products on antiviral activity in terms of structure–activity relationships. This review could provide a foundation for the development of antiviral drugs.
Identification of 6ω-cyclohexyl-2-(phenylamino carbonylmethylthio)pyrimidin-4(3H)-ones targeting the ZIKV NS5 RNA dependent RNA polymerase
Authors: Zhou Guang-Feng , Xie Cong-Qiang , Xue Jian-Xia , Wang Jing-Bo , Yang Yu-Zhuo , Zheng Chang-Bo , Luo Rong-Hua , Yang Ren-Hua , Chen Wen , Yang Liu-Meng , Wang Yue-Ping , Zhang Hong-Bin , He Yan-Ping , Zheng Yong-Tang 
Published: October 2022

Zika virus (ZIKV), a mosquito-borne flavivirus, is a global health concern because of its association with severe neurological disorders such as neonatal microcephaly and adult Guillain-Barre syndrome. Although many efforts have been made to combat ZIKV infection, there is currently no approved vaccines or antiviral drugs available and there is an urgent need to develop effective anti-ZIKV agents. In this study, 26 acetylarylamine-S-DACOs derivatives were prepared, and eight of them were found to have inhibitory activity against Zika virus. Among these substances, 2-[(4-cyclohexyl-5-ethyl-6-oxo-1,6-dihydropyrimidin-2-yl)thio]-N-(3,5-difluorophenyl)acetamide (4w) with the best anti-ZIKV activity was selected for in-depth study of antiviral activity and mechanism of action. Here, we discovered 4w targeted on the ZIKV NS5 RNA -dependent RNA polymerase (RdRp), which exhibited good in vitro antiviral activity without cell species specificity, both at the protein level and at the RNA level can significantly inhibit ZIKV replication. Preliminary molecular docking studies showed that 4w preferentially binds to the palm region of NS5A RdRp through hydrogen bonding with residues such as LYS468, PHE466, GLU465, and GLY467. ZIKV NS5 RdRp enzyme activity experiment showed that 4w could directly inhibit ZIKV RdRp activity with EC50 = 11.38 ± 0.51 μM. In antiviral activity studies, 4w was found to inhibit ZIKV RNA replication with EC50 = 6.87 ± 1.21 μM. ZIKV-induced plaque formation was inhibited with EC50 = 7.65 ± 0.31 μM. In conclusion, our study disclosed that acetylarylamine-S-DACOs is a new active scaffolds against ZIKV, among which compound 4w was proved to be a potent novel anti-ZIKV compound target ZIKV RdRp protein. These promising results provide a future prospective for the development of ZIKV RdRp inhibitors.
In situ growing 3D-Cu coating to improve the reversibility and reaction kinetics of Zn metal anodes
Authors: Liang Lianbao , Hang Lifeng , Xie Shuangcong , Men Dandan , Jiang Guihua , Chen Yiyu 
Published: October 2022

The zinc metal anode is the most promising metal anode material in aqueous battery systems due to its low cost and high theoretical capacity. However, it still undergoes irreversible reactions such as premature failure of the dendrites/dead Zn during Zn stripping/plating, resulting in the inferior cycling stability of the Zn-based full cell. Here, we demonstrate a facile 3D-Cu alloy coating to improve Zn reversibility by providing spatial voids to accommodate the plated Zn to form dendrite-free morphology. Combining the larger 3D surface and the alloying–dealloying process, the Zn anode reactions exhibit enhanced reaction kinetics to meet large operating current densities. The 3D-Cu-coated Zn anode can deliver improved cycling stability for 350 h under a large areal capacity of 3 mAh cm−2. It also enables MnO2–Zn at the full cell level to achieve a specific capacity of 205 mAh g−1 and longer cycling for 350 cycles with 87.4% retention of the initial capacity. This research provides a new pathway to achieve high reversible Zn metal chemistry.
A multiplex pneumonia panel for diagnosis of hospital-acquired and ventilator-associated pneumonia in the era of emerging antimicrobial resistance
Authors: Jitmuang Anupop , Puttinad Soravit , Hemvimol Sivaporn , Pansasiri Siri , Horthongkham Navin 
Published: October 2022

BackgroundAntimicrobial resistance (AMR), including multidrug (MDR) and extensively drug-resistant (XDR) bacteria, is an essential consideration in the prevention and management of hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP). In the AMR era, the clinical utility of the BioFire FilmArray Pneumonia Panel Plus (BFPP) to diagnose HAP/VAP has not been thoroughly evaluated.MethodsWe enrolled adult hospitalized patients with HAP or VAP at Siriraj Hospital and Saraburi Hospital from July 2019–October 2021. Respiratory samples were collected for standard microbiological assays, antimicrobial susceptibility testing (AST), and the BFPP analysis.ResultsOf 40 subjects, 21 were men. The median duration of HAP/VAP diagnoses was 10.5 (5, 21.5) days, and 36 endotracheal aspirate and 4 sputum samples were collected. Standard cultures isolated 54 organisms—A. baumannii (37.0%), P. aeruginosa (29.6%), and S. maltophilia (16.7%). 68.6% of Gram Negatives showed an MDR or XDR profile. BFPP detected 77 bacterial targets—A. baumannii 32.5%, P. aeruginosa 26.3%, and K. pneumoniae 17.5%. Of 28 detected AMR gene targets, CTX-M (42.5%), OXA-48-like (25%), and NDM (14.3%) were the most common. Compared with standard testing, the BFPP had an overall sensitivity of 98% (88-100%), specificity of 81% (74-87%), positive predictive value of 60% (47-71%), negative predictive value of 99% (96-100%), and kappa (κ) coefficient of 0.64 (0.53-0.75). The concordance between phenotypic AST and detected AMR genes in Enterobacterales was 0.57. There was no concordance among A. baumannii, P. aeruginosa, and S. aureusConclusionsThe BFPP has excellent diagnostic sensitivity to detect HAP/VAP etiology. The absence of S. maltophilia and discordance of AMR gene results limit the test performance.
Occluded vein as a predictor for complications in non-infectious transvenous lead extraction
Authors: Milman Anat , Leshem Eran , Massalha Eias , Jia Karen , Meitus Amit , Kariv Saar , Shafir Yuval , Glikson Michael , Luria David , Sabbag Avi , Beinart Roy , Nof Eyal 
Published: October 2022

BackgroundThe use of cardiovascular implantable electronic device (CIED) is steadily increasing, and complications include venous occlusion and fractured leads. Transvenous lead extraction (TLE) can facilitate the re-implantation of new leads.AimsThis study aims to explore predictors and complications of non-infectious TLE.MethodsThis study involves a retrospective analysis and comparison of characteristics, complications, and outcomes of patients with and without occluded veins (OVs) undergoing TLE at our center.ResultsIn total, eighty-eight patients underwent TLE for non-infectious reasons. Indications for TLE were lead malfunction (62; 70.5%) and need for CIED upgrade (22; 25%). Fourteen patients referred due to lead malfunction had an OV observed during venography. The OV group (36 patients) were significantly older (65.7 ± 14.1 vs. 53.8 ± 15.9, p = 0.001) and had more comorbidities. Ejection fraction (EF) was significantly lower for the OV group (27.5 vs. 57.5%, p = 0.001) and had a longer lead dwelling time (3,226 ± 2,324 vs. 2,191 ± 1,355 days, p = 0.012). Major complications were exclusive for the OV group (5.5% vs. none, p = 0.17), and most minor complications occurred in the OV group as well (33.3 vs. 4.1%, p &lt; 0.001). Laser sheath and mechanical tools for TLE were frequently used for OV as compared to the non-occluded group (94.4 vs. 73.5%, respectively, p = 0.012). Procedure success was higher in the non-occluded group compared to the OV group (98 vs. 83.3%, respectively, p = 0.047). Despite these results, periprocedural mortality was similar between groups.ConclusionAmong the TLE for non-infectious reasons, vein occlusion appears as a major predictor of complex TLE tool use, complications, and procedural success. Venography should be considered prior to non-infectious TLE to identify high-risk patients.
Postoperative anion gap associates with short- and long-term mortality after cardiac surgery: A large-scale cohort study
Authors: Li Jiajing , Tian Yu , Wang Lingzhi , Chen Jiayue , Chen Xiaoshu , Huang Huansen , Li Yihao 
Published: October 2022

ObjectiveTo investigate whether postoperative anion gap (AG) is associated with short- and long-term mortality in patients following cardiac surgery.Materials and methodsWe conducted a retrospective cohort study of adults who underwent cardiac surgery from the Medical Information Mart for Intensive Care - III database. The generalized additive model (GAM), logistic regression, and Cox regression were performed to assess the correlations between AG levels and in-hospital, 90-day, and 4-year mortality. Linear regression was used to evaluate the associations between AG and length of stay (LOS).ResultsTotally, 6,410 subjects were enrolled in this study and classified into tertiles based on the initial AG levels. The GAM indicated a positive association between initial AG and in-hospital mortality after adjusting for potential confounders. Multivariate logistic analysis revealed that the risk of in-hospital mortality was higher among patients in tertile 2 (OR 2.05, 95% CI 1.11–3.76, P = 0.021) and tertile 3 (OR 4.51, 95% CI 2.57–7.91, P &lt; 0.001) compared with those in tertile 1. For 90-day and 4-year mortality, multivariate Cox regression found similar associations between AG tertiles and mortality. The LOS in ICU and hospital also increased as AG tertiles increased. The E-value indicated robustness to unmeasured confounders.ConclusionThis study found a positive association between postoperative AG levels and short- and long-term mortality among patients after cardiac surgery. This relationship warrants further research.