bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seizure count forecasting to aid diagnostic testing in epilepsy
Authors: Wang Emily T. , Chiang Sharon , Cleboski Stephen , Rao Vikram R. , Vannucci Marina , Haneef Zulfi 
Published: September 2022

AbstractObjectiveEpilepsy monitoring unit (EMU) admissions are critical for presurgical evaluation of drug‐resistant epilepsy but may be nondiagnostic if an insufficient number of seizures are recorded. Seizure forecasting algorithms have shown promise for estimating the likelihood of seizures as a binary event in individual patients, but methods to predict how many seizures will occur remain elusive. Such methods could increase the diagnostic yield of EMU admissions and help patients mitigate seizure‐related morbidity. Here, we evaluated the performance of a state‐space method that uses prior seizure count data to predict future counts.MethodsA Bayesian negative‐binomial dynamic linear model (DLM) was developed to forecast daily electrographic seizure counts in 19 patients implanted with a responsive neurostimulation (RNS) device. Holdout validation was used to evaluate performance in predicting the number of electrographic seizures for forecast horizons ranging 1–7 days ahead.ResultsOne‐day‐ahead prediction of the number of electrographic seizures using a negative‐binomial DLM resulted in improvement over chance in 73.1% of time segments compared to a random chance forecaster and remained >50% for forecast horizons of up to 7 days. Superior performance (mean error = .99) was obtained in predicting the number of electrographic seizures in the next day compared to three traditional methods for count forecasting (integer‐valued generalized autoregressive conditional heteroskedasticity model or INGARCH, 1.10; Croston, 1.06; generalized linear autoregressive moving average model or GLARMA, 2.00). Number of electrographic seizures in the preceding day and laterality of electrographic pattern detections had highest predictive value, with greater number of electrographic seizures and RNS magnet swipes in the preceding day associated with a higher number of electrographic seizures the next day.SignificanceThis study demonstrates that DLMs can predict the number of electrographic seizures a patient will experience days in advance with above chance accuracy. This study represents an important step toward the translation of seizure forecasting methods into the optimization of EMU admissions.
Impact of warming and deoxygenation on the habitat distribution of Pacific halibut in the Northeast Pacific
Authors: Franco Ana C. , Kim Hongsik , Frenzel Hartmut , Deutsch Curtis , Ianson Debby , Sumaila U. Rashid , Tortell Philippe D. 
Published: September 2022

AbstractOcean warming and deoxygenation are already modifying the habitats of many aerobic organisms. Benthic habitat in the Northeast Pacific is sensitive to deoxygenation, as low oxygen concentrations occur naturally in continental shelf bottom waters. Here, we examine the potential impacts of deoxygenation and ocean warming on the habitat distribution of Pacific halibut (Hippoglossus stenolepis), one of the most commercially important groundfish in North America. We combine fisheries‐independent Pacific halibut survey data (1998–2020) with oceanographic measurements and a regional ocean circulation model to investigate current and future (end of 21st century) influences of deoxygenation and warming on optimal Pacific halibut habitat. We use the observations and model output to derive a metabolic index of Pacific halibut‐specific suitable habitat. Our results show high Pacific halibut counts in regions where the metabolic index is greatest and demonstrate that interannual variability in Pacific halibut abundance is coherent with the Pacific Decadal Oscillation. Working with model projections, we examine potential future changes in suitable Pacific halibut habitat by the end of the century under a high carbon dioxide emissions scenario. These projections indicate that suitable Pacific halibut habitat may largely disappear off the coast of Washington state, retreating approximately 5° latitude northward. In bottom waters along coastal British Columbia and Alaska continental shelf, Pacific halibut habitat is projected to decrease by about 50%. Such habitat changes may potentially drive a northward shift in Pacific halibut, with significant implications for commercial fisheries.
Production of diverse brGDGTs by Acidobacterium Solibacter usitatus in response to temperature, pH, and O2 provides a culturing perspective on brGDGT proxies and biosynthesis
Authors: Halamka Toby A. , Raberg Jonathan H. , McFarlin Jamie M. , Younkin Adam D. , Mulligan Christopher , Liu Xiao‐Lei , Kopf Sebastian H. 
Published: September 2022

AbstractBranched glycerol dialkyl glycerol tetraethers (brGDGTs) are bacterial membrane lipids that are frequently employed as paleoenvironmental proxies because of the strong empirical correlations between their relative abundances and environmental temperature and pH. Despite the ubiquity of brGDGTs in modern and paleoenvironments, the source organisms of these enigmatic compounds have remained elusive, requiring paleoenvironmental applications to rely solely on observed environmental correlations. Previous laboratory and environmental studies have suggested that the globally abundant bacterial phylum of the Acidobacteria may be an important brGDGT producer in nature. Here, we report on experiments with a cultured Acidobacterium, Solibacter usitatus, that makes a large portion of its cellular membrane (24 ± 9% across all experiments) out of a structurally diverse set of tetraethers including the common brGDGTs Ia, IIa, IIIa, Ib, and IIb. Solibacter usitatus was grown across a range of conditions including temperatures from 15 to 30°C, pH from 5.0 to 6.5, and O2 from 1% to 21%, and demonstrated pronounced shifts in the degree of brGDGT methylation across these growth conditions. The temperature response in culture was in close agreement with trends observed in published environmental datasets, supporting a physiological basis for the empirical relationship between brGDGT methylation number and temperature. However, brGDGT methylation at lower temperatures (15 and 20°C) was modulated by culture pH with higher pH systematically increasing the degree of methylation. In contrast, pH had little effect on brGDGT cyclization, supporting the hypothesis that changes in bacterial community composition may underlie the link between cyclization number and pH observed in environmental samples. Oxygen concentration likewise affected brGDGT methylation highlighting the potential for this environmental parameter to impact paleotemperature reconstruction. Low O2 culture conditions further resulted in the production of uncommon brGDGT isomers that could be indicators of O2 limitation. Finally, the production of brGTGTs (trialkyl tetraethers) in addition to the previously discovered iso‐C15‐based mono‐ and diethers in S. usitatus suggests a potential biosynthetic pathway for brGDGTs that uses homologs of the archaeal tetraether synthase (Tes) enzyme for tetraether synthesis from diethers.
Comprehensive review of advances in the field of chalcogenide glass microresonators
Authors: Suresh Soumya , Thomas Sheenu 
Published: September 2022

AbstractChalcogenide glasses (ChGs) are technologically superior materials, and their properties underpin the demands of whispering gallery mode–based integrated photonic devices. The prime focus of this review is to showcase the recent advances in the field of ChG highQcavities. The review also covers the theoretical research aspects and brief on the research challenges and limitations involved in the topic.
Patient satisfaction with telehealth versus in‐person visits during COVID‐19 at a large, public healthcare system
Authors: Chen Kevin , Lodaria Komal , Jackson Hannah B. 
Published: September 2022

AbstractRationaleDuring the coronavirus disease pandemic, audio‐only and video telehealth visits became more widely available, but the relative patient satisfaction between telehealth and in‐person modalities is not well‐described.Aims and ObjectivesOur objective was to compare patient satisfaction with audio‐only, video, and in‐person adult primary care visits at a large, urban public healthcare system.MethodsIn this cross‐sectional study, we used aggregated data from Press Ganey patient satisfaction surveys at 17 primary care facilities at New York City Health + Hospitals for visits between 1 June 2021 to 30 November 2021. We compared mean scores for questions common to surveys for each modality in domains of Access, Care Provider, and Overall Assessment using pairwise comparisons with two‐tailed t‐tests.ResultsThere were 7,183/79,562 (9.0%) respondents for in‐person visits and 1,009/15,092 (6.7%) respondents for telehealth visits. Compared to respondents for in‐person visits, respondents for telehealth visits were more likely to be aged 35–64 years, Asian, and speak English as their primary language, and less likely to be ≥65 years old, Black or other race, and speak Spanish or another language as their primary language (p < 0.001). Patients reported higher mean satisfaction for Access measures for telehealth visits than in‐person visits (p < 0.001). For Care Provider satisfaction questions, video visits generally had higher mean scores than in‐person and, in turn, audio‐only visits. For Overall Assessment questions, video visits had higher mean scores than in‐person and, subsequently, audio‐only visits.ConclusionOf the visit modalities, video visits had the highest mean satisfaction scores across all domains. Telehealth may improve experiences with access, but audio‐only visits may provide poorer visit experiences.
Interpopulation trophic niches and ontogenetic shifts of a mangrove fish predator
Authors: Qin Jiao , Liu Fengming , Schmidt Bjorn Victor , Sun Zhuoxin , Kong Lingwei , Yan Yunrong 
Published: September 2022

AbstractFish trophic niches reflect important ecological interactions and provide insight into the structure of mangrove food webs. Few studies have been conducted in mangrove fish predators to investigate interpopulation trophic niches and ontogenetic shifts. Using stable isotope analysis and two complementary approaches, the authors investigated trophic niche patterns within and between two ontogenetic groups (juveniles and sub‐adults) of a generalist predator (Acentrogobius viridipunctatus) in four mangroves with heterogeneous environmental conditions (e.g., tidal regimes, salinity fluctuations and mangrove tree community). The authors hypothesized that the trophic niche between populations would vary regionally and trophic position would increase consistently from juvenile to sub‐adult stages. The results revealed that both δ13C and δ15N values varied greatly across populations and between ontogenetic groups, and complex spatio‐ontogenetic variations were expressed by Layman's metrics. They also found some niche separation in space, which is most likely related to resource availability in spatially diverse ecosystems. In addition, trophic niche position increased consistently from juveniles to sub‐adults, indicating ontogenetic feeding shifts. The isotopic plasticity index and Fulton's condition index also showed significant spatial‐ontogenetic variation, which is consistent with optimal foraging theory. The findings highlight that trophic plasticity has a high adaptive value for mangrove fish predators in dynamic ecosystems.
Foam mat dried tamarillo powder: Effect of foaming agents on drying kinetics, physicochemical and phytochemical properties
Authors: Rohilla Shubham , Mahanta Charu Lata 
Published: September 2022

AbstractEgg albumin (ALB), whey protein concentrate (WPC), soy protein concentrate (SPC), and gelatin (GEL) at 5% and 10% levels were used to develop foam mat dried tamarillo powder. The logarithmic model gave the best fit for drying of the foams. Powder samples with SPC and WPC as the foaming agents at 10% level possessed better powder quality, and least effective was gelatin. Increase in concentration of the four foaming agents to 10% improved the retention of phytochemical components in the powder, especially WPC. Highest concentration of gallic acid (890 μg/g), chlorogenic acid (403 μg/g), caffeic acid (85 μg/g) and p‐coumaric acid (297 μg/g) among the phenolic acids, and β‐cryptoxathin (27.47 μg/g) and β‐carotene (19.47 μg/g) were determined in WPC‐10P. Foam stability and powder properties of WPC were the best. This study will be directly helpful in the development and commercialization of novel food products using tamarillo fruit powder.Novelty impact statementTamarillo fruit is seasonal in nature and foam mat drying, which is a very economical and convenient way for processing of the pulp and puree into powder, can be used to process the fruit. The findings of this study revealed that foam mat dried powder of tamarillo made with 10% WPC maintains more phytochemicals and has good physicochemical properties. Tamarillo powder has high potential to be used as a reconstituted drink in instant soup or as a food additive in novel foods.
Physico‐chemical, structural, and functional properties of protein concentrate from selected pulses: A comparative study
Authors: Ruckmangathan Sivasankari , Ganapathyswamy Hemalatha , Sundararajan Amutha , Thiyagamoorthy Umamaheswari , Green Rick , Subramani Thirukkumar 
Published: September 2022

AbstractThe selected pulses viz., chickpea, faba bean, red lentil, and red gram were used for the extraction of protein concentrates using alkaline extraction followed by the isoelectric precipitation. The effect of processing on moisture, protein, lipid, ash, and carbohydrate content of pulse flours and respective protein concentrates (PC) ranged between 5.05% and 13.40%; 17.10% and 84.80%; 1.09% and 5.30%; 2.24% and 3.27%; 3.37 and 60.90%, respectively. The amino acid profile of the pulse protein concentrates (PPC) was on par with that of soybean PC and meets the amino acid requirements of children and adults as per the FAO (Food and Agriculture Organization) specifications. The PC had a smaller particle size (126.70–192.70 nm) than pulse flours (251.90–301.90 nm). Water holding capacity (WHC) and oil holding capacity (OHC) of PC were higher than pulse flours. The solubility of protein concentrates was high at acidic and alkaline pH and low at pH 4.5 (isoelectric pH). The significant reduction in anti‐nutritional factors and better protein digestibility resulted from processing of pulse flours. The processing of pulses into PC will serve as a potential functional food ingredient in various food formulations.Novelty impact statementPulses are processed for the extraction of their fractions and utilized for better food product development. In this research, pulse protein concentrate was extracted from easily available pulses for better utilization and the properties were studied for the development of PPC‐incorporated food products similar to soy protein. In the future, all pulse proteins can be used as alternative proteins for soybean to meet our nutritional requirements in a cheaper manner.
Gel formation of scallop (Patinopecten yessoensis) male gonad hydrolysates combined with κ‐carrageenan and locust bean gum
Authors: Wang Xue‐Chen , Cui Xiao‐Fan , Du Yi‐Nan , Xu Shi‐Qi , Wang Yu‐Qiao , Wu Hai‐Tao 
Published: September 2022

AbstractThe gel properties and microstructure of scallop male gonad hydrolysates (SMGHs) were investigated by combing with κ‐carrageenan (κ‐C) and locust bean gum (LBG). It was shown that the initial elastic module of SMGHs/κ‐C 0.1 Hz got marked improvement from 202.3 Pa to 326.7 Pa and the melting temperature also increased 6°C with the addition of LBG. According to the data of low‐field nuclear magnetic resonance, the relaxation time T23 markedly reduced in SMGHs/κ‐C/LBG, representing the migration of water might result in a strong bind among SMGHs, κ‐C, and LBG. Fourier transform infrared spectroscopy showed the existence of hydrogen bonding between LBG and SMGHs/κ‐C. Low‐temperature scanning electron microscopy showed that the SMGHs/κ‐C/LBG ternary complexes possessed smaller voids and more dense network structures. These results could provide more possibilities for the application of SMGHs and polysaccharide complexes in functional hydrogel development.Novelty impact statementWe evaluated the gel and microstructure properties of ternary composite gel consisted of protein hydrolysates from male gonad of scallop (Patinopecten yessoensis) (SMGHs), κ‐carrageenan (κ‐C), and locust bean gum (LBG). The results showed that the addition of κ‐C and LBG significantly improved the gel properties of SMGHs.
Volatile compounds profile and quality of “Cripps pink” apple: Impact of dynamic controlled atmosphere combined to delayed storage and 1‐MCP treatment
Authors: Ludwig Vagner , Thewes Fabio R. , Brackmann Auri , Both Vanderlei , Wagner Roger , Wendt Lucas M. , Berghetti Magno R. P. , dos Santos Ingrid D. , Thewes Flavio R. , Soldateli Francis J. 
Published: September 2022

AbstractThis study evaluated the effects of delayed storage followed by storage under static controlled atmosphere (CA) and dynamic controlled atmosphere established by respiratory quotient (DCA‐RQ) with and without 1‐methylcyclopropene (1‐MCP) application on quality and volatile profile of “Cripps Pink” apple. A fruit batch was immediately stored at 1.5 ± 0.1°C, and another remained for 7 days at 20°C (delay) until storage. The storage conditions were: (1) CA (1.0 kPa O2 + 1.0 kPa CO2); (2) DCA‐RQ 1.3; (3) DCA‐RQ 1.5. Additionally, for each storage condition and delay strategy, a batch of fruit was treated with 1‐MCP, and another batch was left untreated.Practical applicationsDCA‐RQ 1.3 maintened flesh firmness even without 1‐MCP and with delayed storage. 1‐MCP application reduced all esters. Delayed storage increased the esters concentration and when associated with DCA‐RQ 1.3 and 1.5 should be recommended to reduce decay, increase the healthy fruit amount, and improve the aroma emission of “Cripps Pink” apple.
Application of artificial neural network with metaheuristic optimization for improving the nutritive value of fried fish
Authors: Sadhu Tithli , Lahiri Sandip K. , Bhattacharjee Ashish , Chakrabarty Jitamanyu 
Published: September 2022

AbstractNutritional quality indices of fish deteriorate drastically during frying. In this study, using Catla catla fish and mustard oil (culinary media), extensive experiments are carried out varying the temperature, time, and oil amount to attain the best nutritional quality indices of fried fish with a tuned combination of cooking parameters. An artificial neural network (ANN) is developed to select the best model to find a nonlinear correlation between the frying conditions and nutritional quality indices. ANN‐based metaheuristic optimization methodologies, namely genetic algorithm (GA), differential evolution, firefly optimization, and gray wolf optimization (GWO), are applied to optimize the best cooking conditions. Among these, GWO is most promising for optimizing favorable inputs, practical optimal solutions, and reasonable execution time. As outputs are conflicting, multi‐objective genetic algorithm (MOGA) is implemented for their simultaneous optimization with optimum values of process variables for health benefit, reducing frying time, and minimizing the wastage of culinary media. The MOGA successfully improves the ω‐3/ω‐6 fatty acids, polyunsaturated fatty acids/saturated fatty acids, cis/trans fatty acids ratio, and index of atherogenicity values up to 40.43%, 65.35%, 137%, and 83.84%, respectively, satisfying the multi‐objective criteria.Practical applicationsThe conventional frying process of fish is successfully optimized by the developed hybrid “model‐optimization” topology that improves the nutrient value of fried fish significantly. The developed neural model automatically searches all available algorithms and activation functions exhaustively to select the best model. All single‐objective and multi‐objective genetic algorithms integrated with an artificial neural network can attain the optimum successfully for all outputs by a unique tuned cooking condition. Operators can choose the preferred solution among many Pareto optimal combinations as per their needs. Furthermore, this developed, generic topology provides a tool for process modification and optimization of other food process engineering methods.
Effects of vitamin D supplementation on muscle function and recovery after exercise‐induced muscle damage: A systematic review
Authors: Rojano‐Ortega Daniel , Berral‐de la Rosa Francisco J. 
Published: September 2022

AbstractBackgroundVitamin D is essential for the optimal health of the skeletal system. However, this vitamin is also involved in other functions of the human body, such as muscle, immune and inflammatory ones. Some studies suggest that adequate levels of vitamin D support muscular function during exercise and accelerate recovery because they reduce specific pro‐inflammatory cytokine levels, but those results have not always been observed. Therefore, this review aims to evaluate the effects of vitamin D supplementation on inflammation, oxidative stress and recovery after exercise.MethodsThis systematic review was conducted using the Preferred Reporting of Systematic Reviews and Meta‐Analyses (PRISMA) guidelines. A literature search of SPORTDiscuss, PubMed, Web of Science and Scopus was performed from inception through February 2022. The articles' methodological quality was assessed with the PEDro scale.ResultsAfter the application of the inclusion and exclusion criteria, 11 eligible articles were included. All the studies were considered of moderate methodological quality. Ten studies involved regular vitamin D supplementation for more than 7 days, and one study performed acute vitamin D supplementation 24 h before exercise.ConclusionsThe existing evidence suggests that vitamin D supplementation for periods of more than 1 week with a minimum dose of 2000 IU/day appears to be an efficacious strategy for attenuating muscle damage and inflammation after exercise. The potential positive effects on muscle function, muscle pain and oxidative stress need to be confirmed with new investigations. Further research is also required to determine the adequate vitamin D dosage to obtain positive effects without adverse effects.