bluuebunny/crossref_metadata_2025_split huggingface dataset:
[3 + 2] Cycloadditions in Asymmetric Synthesis of Spirooxindole Hybrids Linked to Triazole and Ferrocene Units: X-ray Crystal Structure and MEDT Study of the Reaction Mechanism
Authors: Al-Rasheed Hessa H. , Al-Majid Abdullah Mohammed , Ali M. , Haukka Matti , Ramadan Sherif , Soliman Saied M. , El-Faham Ayman , Domingo Luis R. , Barakat Assem 
Published: October 2022

Derivatization of spirooxindole having triazole and ferrocene units was achieved by the [3 + 2] cycloaddition (32CA) reaction approach. Reacting the respective azomethine ylide (AY) intermediate generated in situ with the ethylene derivative produced novel asymmetric cycloadducts with four contiguous asymmetric carbons in an overall high chemical yield with excellent regioselectivity and diastereoselectivity. X-Ray single-crystal structure analyses revealed, with no doubt, the success of the synthesis of the target compounds. The 32CA reaction of AY 5b with ferrocene ethylene 1 has been studied within MEDT. This 32CA reaction proceeds via a two-stage one-step mechanism involving a high asynchronous transition state structure, resulting from the nucleophilic attack of AY 5b on the β-conjugated position of ferrocene ethylene 1. The supernucleophilic character of AY 5b and the strong electrophilic character of ferrocene ethylene 1 account for the high polar character of this 32CA reaction. Further, Hirshfeld analyses were used to describe the molecular packing of compounds 4b, 4e, 4h and 4i.
Association of Bradycardia and Asystole Episodes with Dialytic Parameters: An Analysis of the Monitoring in Dialysis (MiD) Study
Authors: Soomro Qandeel H. , Bansal Nisha , Winkelmayer Wolfgang C. , Koplan Bruce A. , Costea Alexandru I. , Roy-Chaudhury Prabir , Tumlin James A. , Kher Vijay , Williamson Don E. , Pokhariyal Saurabh , McClure Candace K. , Charytan David M. 
Published: October 2022

Key Points

There were 551 cases of clinically significant bradyarrhythmia or asystole (CSBA) that occurred in the last 12 hours of the interdialytic interval preceding 100 of 4424 dialysis sessions.We did not find significant associations between dialytic parameters or electrolytes and CSBA in the last 12 hours of the interdialytic period.Association of laboratory and dialytic factors with CSBA from one session to the next were not significant except dialysate sodium concentrations <135 mEq/L.

Background
Bradycardia and asystole events are common among patients treated with maintenance hemodialysis. However, triggers of these events in patients on maintenance hemodialysis (HD), particularly during the long interdialytic period when these events cluster, are uncertain.

Methods
The Monitoring in Dialysis Study (MiD) enrolled 66 patients on maintenance HD who were implanted with loop recorders and followed for 6 months. We analyzed associations of predialysis laboratory values with clinically significant bradyarrhythmia or asystole (CSBA) during the 12 hours before an HD session. Associations with CSBA were analyzed with mixed-effect models. Adjusted negative binomial mixed-effect regression was used to estimate incidence rate ratios (IRR) for CSBA. We additionally evaluated associations of CSBA at any time during follow-up with time-averaged dialytic and laboratory parameters and associations of peridialytic parameters with occurrence of CSBA from the start of one HD session to the beginning of the next.

Results
There were 551 CSBA that occurred in the last 12 hours of the interdialytic interval preceding 100 HD sessions in 12% of patients and 1475 CSBA events in 23% of patients overall. We did not identify significant associations between dialytic parameters or serum electrolytes and CSBA in the last 12 hours of the interdialytic interval in adjusted analyses. Median time-averaged ultrafiltration rate was significantly higher in individuals without CSBA (9.8 versus 8, P=0.04). Use of dialysate sodium concentrations ≤135 (versus 140) mEq/L was associated with a reduced risk of CSBA from the start of one session to the beginning of next.

Conclusions
Although a few factors had modest associations with CSBA in some analyses, we did not identify any robust associations of modifiable parameters with CSBA in the MiD Study. Further investigation is needed to understand the high rates of arrhythmia in the hemodialysis population.
Fabrication of ceramic scintillators by laser sintering: the case of Lu3Al5O12:Pr
Authors: Shao Y. , Conner R. L. , Souza N. R. S. , Silva R. S. , Jacobsohn L. G. 
Published: October 2022

Abstract
The fabrication of ceramic scintillators by laser sintering is briefly reviewed and current limitations discussed. The experimental work focused on the fabrication and characterization of undoped and Pr-doped Lu3Al5O12 (LuAG). X-ray diffraction (XRD) and Raman spectroscopy were used to characterize the structure of the sintered ceramics, with XRD results suggesting the absence of residual thermal stresses. Collectively, Raman results suggested the incorporation of Pr to affect the structure and its dynamics. Broadening the peaks of the ceramics in relation to those from the single crystal revealed the presence of structural disorder. Scanning electron microscopy revealed intergrain porosity thus explaining the lack of optical transparency. Energy-dispersive X-ray spectroscopy (EDX) measurements showed Pr to be homogeneously distributed. Radioluminescence measurements under X-ray excitation as a function of the temperature were used to investigate intrinsic defects of the host, including anti-sites and F-type defects.
Hubungan Penggunaan Bedak Tabur pada Area Genetalia Bayi Usia 0-9 Bulan Terhadap Kejadian Diaper Rash di PMB Fadilah Desa Bulukagung Madura
Authors: Khairoh Miftakhul , Roosyaria Arkha 
Published: October 2022

Ruam popok atau sering disebut dengan diaper rash adalah ruam merah terang disebabkan oleh iritasi dari kulit yang terkena urine atau kotoran yang berlangsung lama di bawah popok anak. Kulit bayi masih sensitif disebabkan fungsi-fungsinya yang masih terus berkembang terutama pada lapisan epidermis atau lapisan terluar kulit. Penelitian ini menganalisis hubungan penggunaan bedak tabur pada area genetalia bayi usia 0-9 bulan terhadap kejadian diaper rash di PMB Fadilah Desa Bulukagung Madura. Penelitian korelasi, cross sectional, Populasi sebanyak 23 bayi usia 0-9 bulan yang mengalami diaper rash, sampel sebanyak 23 bayi, Purposive Sampling, pengumpulan data observasi , alat ukur cheklist, analisis chi square, α (0,05).
Hubungan penggunaan bedak tabur pada area genetalia bayi usia 0-9 bulan terhadap kejadian diaper rash, didapat bahwa dari 23 bayi yang mengalami diaper rash dan diberikan bedak tabur pada area genetalia 15 (80%) bayi yaitu sebagian besar mengalami kejadian diaper rash berat. Hasil analisa statistik dengan uji chi square, diperoleh hasil ρ = 0.000 dengan taraf 0,05 yang berarti ρ=0,000 <0,05 maka ada hubungan penggunaan bedak tabur pada area genetalia bayi usia 0-9 bulan terhadap kejadian diaper rash. Kesimpulan : Adanya hubungan penggunaan bedak tabur pada area genetalia bayi usia 0-9 bulan terhadap kejadian diaper rash di PMB Fadilah Desa Bulukagung Madura.
Perbedaan antara Pemijatan Rolling Massage dan Counterpresure Massage pada Ibu Bersalin Kala I Fase Aktif terhadap Penurunan Skala Nyeri pada Persalinan Kala 1 Fase Aktif Di PMB Domingas S.ST, M.Kes Surabaya
Authors: Rosyaria Arkha , Ummah Kholifatul 
Published: October 2022

Nyeri persalinan merupakan kondisi fisiologis yang secara umum dialami oleh hampir semua ibu bersalin. Selama persalinan dan kelahiran pervaginam, nyeri disebabkan oleh kontraksi rahim.dilatasi serviks,dan distensi perinium.pada studi pendahuluan di PMB Domingas SST.M.Kes pada 14 ibu bersalin kala 1 fase aktif di dapatkan hasil 13 (92,85%) ibu bersalin merasakan nyeri pada saat persalinan. Penelitian ini bertujuan untuk mengetahui perbedaan antara pemijatan rolling massase dan counterpresure massase pada ibu bersalin kala I fase aktif terhadap penurunan skala nyeri pada persalinan kala I fase aktif. Tempat penelitian di laksanakan di PMB Domingas SST.M.kes. Selama 3-4 minggu. Penelitian menggunakan pendekatan Quesi eksperimental dengan two group desain post-test. Berdasarkan hasil uji chi square diperoleh nilai p value 0,05 jika p value < nilai α 0,05, maka H0 ditolak dan H1 diterima. Hal ini menunjukan adanya pengaruh massage counter pressure terhadap tingkat nyeri ibu bersalin primigravida kala I fase aktif. Hasil : Dari 7 ibu bersalin yang diberikan rolling massage didapatkan 3 ibu bersalin (42,85% dengan nyeri sedang, 3 ibu bersalin (42,85%) dengan nyeri ringan berat dan 1 ibu bersalin (14,2%) dengan nyeri sangat berat. Sedangkan 7 ibu bersalin yang diberikan counterpresure didapatkan 6 ibu bersalin (85,7%) dengan nyeri ringan dan 1 ibu bersalin (14,2%) dengan nyeri sedang. Kesimpulan : Hal ini menunjukan adanya pengaruh pemijatan rolling massage dan counterpressure terhadap tingkat nyeri ibu bersalin kala 1 fase aktif di PMB Domingas SST.M.Kes Surabaya.
ANALISIS PENDAPATAN USAHATANI POLA ROTASI TANAMAN PADI-JAGUNG MANIS DI DESA MULYASARI KECAMATAN SUKAMAJU
Authors: Nuryanti Dewi Marwati , Kasim Niken Nur 
Published: October 2022

Penelitian ini dilaksanakan di Desa Mulyasari Kecamatan Sukamaju Kabupaten Luwu Utara, pada bulan Juni-Agustus 2017, bertujuan untuk mengetahui pendapatan usahatani pola rotasi tanaman padi-jagung manis. Desa lokasi penelitian dipilih dengan sengaja dengan pertimbangan jumlah petani yang paling banyak mengusahakan pola rotasi tanaman tersebut. Responden dipilih secara acak sebesar 35%. Data dalam penelitian ini terdiri dari data primer yaitu data yang diperoleh dari responden melalui wawancara dengan bantuan kuisioner dan observasi terhadap obyek yang diteliti, sedangkan data sekunder diperoleh dari Instansi yang terkait dengan penelitian ini. Penelitian ini mengunakan metode analisa biaya dan pendapatan dengan rumus Pi=TRi-TCi, kemudian dilanjutkan dengan analisis R/C untuk mengetahi kelayakan usaha. Hasil penelitian menunjukkan pendapatan usahatani padi adalah sebesar Rp. 8.968.001,- per ha per musim tanam dengan R/C sebesar 2,35, pendapatan usahatani jagung manis adalah sebesar Rp. 8.453.804,- per ha per musim tanam dengan R/C sebesar 1,8 dan usahatani pola rotasi tanaman padi- jagung manis-jagung manis adalah sebesar Rp. 17.186.696,- per ha per tahun dengan R/C 2,01.
ANALISIS PRODUKSI TEMPE BUNGKUS DAUN PISANG DI DESA LOA PARI KECAMATAN TENGGARONG SEBERANG KABUPATEN KUTAI KARTANEGARA (The Production Analysis of Banana Leaves-Wrapped Tempe in Loa Pari Village Tenggarong Seberang Subregency Kutai Kartanegara Regency)
Authors: FEBRIADI VODI , BALKIS SITI 
Published: October 2022

The purposes of this research were to know the production cost, revenue, and profit of tempe production, the influence of soybean usage to tempe production level, total product, average product, and marginal product of production of banana leaves wrapped tempe . The research was conducted from April to June 2016 in the Village of Loa Pari, Subregency of Tenggarong Seberang, Regency of Kutai Kartanegara. Sampling used census method and data were collected by direct observation and interview to 20 respondents. The data were analyzed to calculate total cost, revenue, income, total product, average product, and marginal product. The results of this research showed the average production cost of IDR4,728,311.40 month-1, the average revenue of IDR11,100,000.00 month-1, and the average income of IDR6,371,688.60 month-1. The use of soybeans will affect tempe production. Total production of banana leaves wrapped tempe was 22,200 packs month-1. The average production of banana leaves wrapped tempe was 733 packs days-1. The marginal production of banana leaves wrapped tempe was 25 packs kg-1.
MENINGKATKAN KEMAMPUAN LITERASI NUMERASI SISWA MELALUI PENERAPAN MODEL PEMBELAJARAN PBL BERBASIS STEM
Authors: Wati Gus Lisna , Syafitri Ely 
Published: October 2022

AbstractThe purposeof this study was to determine the improvement of students numeracy literacy skills through a Problem Based Learning (PBL) learning model based on the Science, Technology, Engineering and Mathematics (STEM) approach. This type of research is classroom action research which consists of 2 cycles, with 4 stages,namely planning, implementation, observation and reflection. The instrument used is an observation sheet on the implementation of learning and literacy test. The results of this study indicate that the numeracy literacy skills of students with high and moderate mathematical abilities in general can complete, where students can : (1) work effectively with models in concrete but complex situations, (2) represent different information and relate it to real situations. Analyze numeracy skills in this study the students were grouped. Keywords: Numerical Literacy; Problem Based Learning (PBL) Based On Science, Technology, Engineering, and Mathematics (STEM) Approach; Phytagorean Theorem;
Gambaran Tekanan Darah pada Perokok Elektrik Dikomunitas Vaporizer Rawamangun
Authors: Arifin Robertus 
Published: October 2022

Merokok adalah kebiasaan yang tidak asing lagi di lingkungan masyarakat, mulai dari anak-anak, remaja, dewasa sampai lanjut usia. Rokok elektrik juga dapat meningatkan tekanan darah dalam tubuh seiring perkembangan zaman ditentukan inovasi baru yaitu Vape atau rokok elektrik. Tujuan penelitian ini adalah mengetahui gambaran tekanan darah pada perokok elektrik di Komunitas Vaporizer Rawamangun. Jenis penelitian ini ialah univariat. Penelitian ini dilakukan pada bulan Mei-Juli 2018 di laboratorim STIKes KESOSI dengan menggunakan teknik pengambilan sampel Simple Random Sampling. Populasi pada penelitian ini adalah data perokok elektrik di komunitas vaporizer Rawamangun, Jakarata Timur. 30 Sampel diambil dari 30 anggota Komunitas Vaporizer Rawamangun. Hasil penelitian yang dilakukan pada 30 orang perokok elektrik menunjukkan bahwa kelompok umur 17-21 Tahun memiliki presentase sebesar 20% dengan tekanan darah rendah dan pada umur 22-26 tahun memiliki presentase sebesar 67% dengan tekanan darah normal sedangkan umur 27-28 tahun memiliki presentase sebesar 7% dengan tekanan darah tinggi. Dapat disimpulkan bahwa perokok yang memiliki tekanan darah normal lebih tinggi presentasenya dibanding perokok yang memiliki tekanan darah tinggi dan rendah
Methodological Model for the Research Function in the Professional Training of Lawyers
Authors: Purizaga-Sorroza Maritza Asunciona , Campos-Ugaz Walter Antonio , Campos-Ugaz Osmer , Hernandez Ronald M. , Garcia Flores Lizzeth Aimee 
Published: October 2022

Introduction: The training given at the School of Law, is characterized: the research function is almost not present in the teaching-learning process, a high percentage of teachers are not trained in the management of research skills; there are certain signs of work in active methodologies, a high percentage of graduates graduate through the Special Degree Program, the current curriculum does not train professionals in research skills and abilities, a high percentage of students perceive their teachers with a regular academic performance and many of them have no knowledge of the professional profile of the graduate. Objective: To design a methodological model to develop research skills in the professional training of lawyers. Methodology: It consisted of data collection through: classroom observation, application of surveys to students and teachers. The data collected were subjected to a process of selection, analysis, critique and codification. Result: Design of a methodological model based on Tobón's competency-based approach and the Tunning Project, the theory of critical-humanistic teaching and Jorge Witker's theory of active education. Contribution: The proposed methodological model, will allow the strengthening of scientific competencies in the training process at the Law School and would constitute one of the most significant changes in legal education and would allow a wide incidence in the university sphere.
ANALYSIS OF STUDENTS UNDERSTANDING TOWARD ONLINE LEARNING BY USING GOOGLE CLASSROOM DURING THE PANDEMIC COVID-19 AT SMA PELITA NGABANG CLASS X IPS IN ACADEMIC YEAR 2021/2022, LANDAK REGENCY
Authors: Rita Rita , Tuminah Tuminah , Selong Yustina 
Published: October 2022

This study aims to determine students' understanding toward online learning using Google Classroom during the Pandemic Covid-19 at SMA Pelita Ngabang. Beside that, the researchers conducted this research to find out the obstacles that students face during online learning using Google Classroom. This research is a qualitative descriptive which conducted in tenth grade students of SMA Pelita Ngabang. Data collection techniques used were closed questionnaire, interview, and documentation related to the sources related to this research. The results of the questionnaire and the results of interview with students can be concluded that currently there were many students of tenth grade students at SMA Pelita Ngabang understand how to use Google Classroom although there were some students who did not understand how to use Google Classroom during the pandemic Covid-19. The process of online learning by using media Google Classroom was very appropriate to be applied during the pandemic Covid-19. Nevertheless, there were some obstacles that students often face when participating in the online learning process because of limited facilities such as Android phones. In addition, they often change their email passwords that could make them difficult to login because they forgot their email passwords. Regarding the network that was not good during the online learning process using Google Classroom was also became an obstacle in the teaching and learning process.
Requiem, d’Antonio Tabucchi ou l’aventure portugaise d’un Italien
Authors: López Montagut Aina 
Published: October 2022

L’alloglossie peut s’expliquer de différentes façons : que ce soit pour des raisons politiques, socio-culturelles, affectives ou d’autres encore, les auteurs concernés justifient tant bien que mal leurs choix linguistiques. Qu’ils se contentent d’écrire dans la langue autre, ou qu’ils décident de créer un pont littéraire entre deux systèmes linguistiques, les écrits qu’ils produisent traduisent la volonté et parfois même la preuve d’une acquisition linguistique, ainsi qu’une grande intercompréhension entre les langues utilisées.Nous nous intéresserons ici au cas de l’auteur italien Antonio Tabucchi, et tout particulièrement au roman Requiem (1991), écrit en portugais. Cet exemple est d’autant plus intéressant que l’auteur a refusé de s’autotraduire en italien, laissant ainsi la traduction à un autre locuteur de sa langue maternelle. Tabucchi justifie très clairement le pourquoi de ce choix de langue d’écriture, qui s’est imposé à lui comme une évidence.
Psychological burden of coronavirus disease 2019 pandemic among Egyptian pregnant women
Authors: Halim Hala W.A. , Abd Elaziz Shimaa Y. , Fathy Doaa S.A. 
Published: October 2022

Background and aim
Pregnant women are more prone to psychological distress, which can have a deleterious effect on the mother and the fetus. coronavirus disease 2019 (COVID-19) pandemic is a new and dangerous event with limited data available that may adversely affect the mental health of pregnant women. So, the aim of this study was to assess the psychosocial effect of the COVID-19 pandemic on pregnant women, pregnant women’s perceptions toward COVID-19 epidemiology, and antenatal care service utilization during the pandemic.

Patients and methods
This cross-sectional study was carried out in the interval from February 2021 to September 2021 and included 340 Egyptian pregnant women with singleton pregnancy during the COVID-19 pandemic. A structured self-administered online questionnaire was completed by the participants. The validated 21-item Depression, Anxiety, and Stress Scale-21 was used.

Results
The study revealed a high prevalence of stress (61.5%), anxiety (73%), and depression (68.5%) among pregnant women. Chronic diseases, irregular antenatal care, and previous COVID-19 infection of family members were all significant predictors of anxiety and depression. In contrast, prior infection of the pregnant women with COVID-19 in the current pregnancy was a significant predictor for stress, anxiety, and depression.

Conclusion
There was a high prevalence of anxiety, depression, and stress among Egyptian pregnant women during the time of the COVID-19 pandemic. Psychosocial support is required, in addition to raising pregnant women’s awareness regarding COVID-19 infection.
Familial Hypercholesterolemia within Cardiology Practice – Single-Center Experience during 2-Year Period
Authors: Begić Edin , Djozic Ada , Karavelic Emina , Zatric Nadira , Sinančević Adela , Džubur Alen , Durak-Nalbantić Azra , Begić Alden , Begić Nedim , Šahbaz Amina , Hasanagić Esma , Gogić Ena , Naser Nabil , Zukić Fuad , Medjedović Edin , Iglica Amer , Halilčević Mirela , Begić Zijo 
Published: October 2022

Background:
Familial hypercholesterolemia (FH) is an inherited disorder characterized by significantly elevated levels of low-density lipoprotein (LDL) cholesterol and is usually diagnosed after the occurrence of major adverse cardiovascular event.

Aim:
The aim of this study was to evaluate FH existence, increase awareness of this disorder, and highlight the importance of early treatment which leads to a reduction of premature cardiovascular events and death.

Methods:
The research had a cross-sectional, descriptive, and analytical character, and included 6881 (n = 6881) patients who were hospitalized in the Clinic for Heart, Blood Vessel and Rheumatic Diseases, Clinical Center University of Sarajevo, Sarajevo, Bosnia and Herzegovina, in the period from January 2019 to January 2021. LDL values were analyzed, and all patients with LDL ≥4 mmol/L were included in the study. The Dutch Lipid Score was calculated for all patients, and the findings of invasive coronary angiography were taken into account in those patients for whom it was performed.

Results:
From 6881 patients, 74 patients had LDL ≥4 mmol/L. Possible FH (score: 3–5) was found in 25 patients, probable FH (score: 6–8) in 2 patients, while the diagnosis of definite FH was not made in any patient. A ST-elevation myocardial infarction was an indication for hospitalization in 44.60% (n = 33), hypertension in 14.87% (n = 11), and angina pectoris in 14.87% (n = 11) of patients. Patients under the age of 65 had higher Dutch Lipid Score compared to the patients above the age of 65, regardless of male or female. Correlational analysis indicated a significant positive relationship between Dutch Lipid Score and level of cholesterol (r =0.385; P < 0.01) and LDL (r = 0.401; P < 0.001). Statistically significant predictors in the explanation of FH were age (β = −0.45; P < 0.001) and LDL (β = 0.52; P < 0.001).

Conclusion:
LDL values and age are the main determinants of the FH existence, and the effect on LDL values should be imperative in clinical practice.