bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peran Lembaga Keuangan Syariah Dalam Pengentasan Kemiskinan Di Provinsi Nusa Tenggara Barat
Authors: Awwalunnisa Nur 
Published: March 2022

ABSTRAK
Kemiskinan merupakan masalah yang akan selalu dihadapi oleh berbagai negara di seluruh dunia yang menyebabkan seluruh negara baik negara maju maupun negara berkembang focus membahas berbagai strategi maupun kebijakan untuk menangani masalah kemiskinan. Salah satu tujuan SDGs adalah menghapus segala bentuk kemiskinan. Tujuan ini didefinikasikan sebagai presentase pendduk yang hidup di bawah garis kemiskinan internasional yaitu mereka yang rata-rata konsumsi hariannya (atau pendapatan) kurang dari $1,25/orang per hari. Dalam ekonomi Islam terdapat instrument yang dapat membantu menyelesaikan masalah kemiskinan yaitu melalui penyaluran zakat dan pengembangan modal melalui Lembaga keuangan syariah baik melalui bank syariah ataupun Lembaga keuangan syariah lainnya. Provinsi Nusa Tenggara Barat sebagai salah satu provinsi di Indonesia yang penduduknya mayoritas muslim seharusnya dapat memberikan kontribusi dalam mengatasi masalah kemiskinan baik secara regional maupun nasional.
Jumlah penduduk miskin di Indonesia pada tahun 2020 mengalami peningkatan jika dibandingkan dengan dua tahun sebelumnya. Salah satu alasan terjadinya peningkatan jumlah penduduk miskin ini karena terjadinya bencana global berupa pandemic covid-19 yang mengharuskan seluruh manusia di dunia melakukan adaptasi terhadap keadaan baru. Pandemic yang telah mengganggu seluruh aktivitas manusia secara keseluruhan termasuk dalam kegiatan ekonomi, mengakibatkan beberapa orang kehilangan pekerjaan dan mata pencaharian. Walaupun secara nasional jumlah penduduk miskin mengalami kenaikan, namun secara regional di Provinsi NTB menunjukkan jumlah penduduk miskin yang menurun pada tahun 2020.
A comparison of the accuracy of the cervical vertebrae maturation stage method and Demirjian’s method on mandibular length growth
Authors: Dewi Alfira Putriana , Pradopo Seno , Nelwan Sindy Cornelia 
Published: March 2022

Background: Malocclusion is one of the most familiar dental problems, with a high prevalence among the population. Understanding the patient’s craniofacial growth and development is crucial in diagnosis, as are the planning and subsequent success of the treatment. Malocclusion needs to be treated early to optimise the outcome achieved by the treatment. One of the most common types of malocclusions observed in clinics is crowding. The craniofacial bone relevant to the treatment of crowding is the mandible, defined as the mandibular length from the condylion to gnathion areas. When planning treatment, clinicians may experience difficulties in determining the biological age of patient, particularly when supporting diagnostic tools are not available. The indicators of biological age can be observed by the assessment of bone maturation using the cervical vertebrae maturation (CVM) method and by the analysis of tooth maturation using Demirjian’s method. However, limited studies are available regarding the accuracy of these methods as diagnostic tools. Purpose: This study aims to analyse the accuracy of the CVM method compared with Demirjian’s method concerning mandibular length growth. Methods: An analytic research method and a cross-sectional design are employed. The research sample comprised 50 lateral cephalometric and panoramic photos of children aged 8-16 years. Data were collected by analysing the maturity level of the cervical vertebrae and the teeth, and measuring the mandible length of the children in the photos. The statistical test used was the Wilcoxon test. Results: The results of the Wilcoxon test for the asymptotic sign had a p-value of 0.116 > 0.05, indicating no significant difference between the CVM and Demirjian methods. Conclusion: Both of the methods noted above yielded equally accurate results for determining mandibular length growth.
The effect of an 8% cocoa bean extract gel on the healing of alveolar osteitis following tooth extraction in Wistar rats
Authors: Isnandar I. , Hanafiah Olivia Avriyanti , Lubis Muhammad Fauzan , Lubis Lokot Donna , Pratiwi Adzimatinur , Erlangga Yeheskiel Satria Yoga 
Published: March 2022

Background: Alveolar osteitis is a well-known complication that occurs following a tooth extraction when the clot within the socket breaks down too early, causing increased localised inflammation and extreme pain. Alveolar osteitis delays the wound healing process of the socket. The polyphenols in the cocoa bean (Theobroma cacao L.) can stimulate the wound healing process. Purpose: The aim of this study was to analyse the effect of an 8% cocoa bean extract gel on the healing of alveolar osteitis following a tooth extraction. Methods: This study is an in vivo experiment with a posttest-only control group design. Thirty-six male Wistar rats were divided into three groups: a negative control, positive control and an 8% cocoa bean extract gel. A tooth extraction was performed on the mandibular incisor, and alveolar osteitis was induced by the application of adrenaline using a paper point on the socket. On the 3rd, 7th and 14th days, the clinical wound size of the extraction socket was measured, and the rats were sacrificed to observe the number of macrophages, fibroblasts and osteoblasts microscopically. A two-way analysis of variance test and post hoc least significant difference test were used to analyse the data (p < 0.05). Results: The data analysis showed a significant difference in the clinical wound size of the extraction socket and the number of macrophages, fibroblasts and osteoblasts between the 8% cocoa bean extract gel and the control groups (p = 0.000). Conclusion: An 8% cocoa bean extract gel stimulates the healing of alveolar osteitis following tooth extraction in Wistar rats.
CORRELATION BETWEEN MATERNAL FACTOR AND STUNTING AMONG CHILDREN OF 6-12 MONTHS OLD IN CENTRAL LOMBOK
Authors: Qurani Ratu M. , Karuniawaty Titi Pambudi , John Ristania Ellya , Wangiyana Ni Komang Ayu Swanitri , Setiadi Qisthinadia Hazhiyah , Tengkawan Jeslyn , Septisari Ayu Anandhika , Ihyauddin Zulfikar 
Published: March 2022

ABSTRACTBackground: Stunting is a child growth and development disorder that has been one of the nutritional problem in children living in developing countries until now. Maternal factor might be one of the risk factors of stunting. Method: This was an analytical observational study with cross sectional design that aimed to identify the correlation between the maternal factor and stunting, especially in children aged 6-12 months in 3 villages in Central Lombok. Result: There were 21,9% (33 of 151) of children suffering from stunting. Based on the maternal factor in stunting children, there were 6,1% of mothers who had low body mass index (BMI), 27,3% of mothers who had low arm circumference, 61% of mothers who had low weight gain during the pregnancy, and 39,4% of mothers who had height <150 cm. Maternal height was the only factor that significantly associated to the incidence of stunting (p = 0.044, OR = 2.3). Conclusion: Based on analysis of several maternal factors, there is a significant correlation between mother’s height and stunting (p<0,05 and OR=2,3). ABSTRAKLatar Belakang: Stunting merupakan gangguan pertumbuhan dan perkembangan pada anak, yang sampai saat ini masih menjadi salah satu masalah gizi anak terutama di negara berkembang. Faktor maternal adalah salah satu faktor risiko stunting. Metode: Penelitian analitik observasional dengan rancangan cross sectional ini bertujuan untuk menganalisis hubungan antara faktor maternal dan stunting pada anak usia 6-12 bulan di 3 desa di Lombok Tengah. Hasil: Terdapat 21,9% (33 dari 151) anak yang mengalami stunting. Berdasarkan faktor maternal pada anak dengan stunting, sebanyak 6,1% memiliki ibu dengan indeks masa tubuh (IMT) rendah, 27,3% memiliki ibu dengan lingkar lengan atas rendah, 61% memiliki ibu dengan peningkatan berat badan yang rendah selama kehamilan, dan 39,4% memiliki ibu dengan tinggi badan <150 cm. Faktor tinggi badan ibu merupakan satu-satunya faktor yang berhubungan signifikan dengan kejadian stunting (p=0,044, OR=2,3). Kesimpulan: Berdasarkan analisis beberapa faktor maternal, terdapat hubungan yang signifikan antara tinggi badan ibu dan stunting (p<0,05 dan OR=2,3).
CORRELATION OF HANDWASHING AND BASIC HOUSEHOLD SANITATION TOWARDS NUTRITIONAL STATUS OF TODDLER (UNDER 2 YEARS OLD/ BADUTA) IN BOJONEGORO DISTRICT
Authors: Haibah Anizah Izzi 
Published: March 2022

ABSTRACTBackground: Nutrition problems in toddlers are still a significant problem both on a global and local scale. Intensive monitoring of nutritional status and controlling various factors related to nutritional status is very important to be done especially in the critical period that is before the child is two years old (Toddler/Baduta). Objective: Analyze the relationship of mother/main caregiver's handwashing and basic household sanitation with the nutritional status of Toddler (under two years old/Baduta) in Mojosari Village, Bojonegoro. Method: This research was a descriptive-analytic with a crosssectional design with the target is the entire population of Toddler (under two years old) that meets the inclusion and exclusion criteria. Data collection was done by questionnaire and observation. Relationship analysis was performed with fisher exact test. Result : This study did not find any significant relationship between hand washing (p = 1 > α (0.05)) and basic household sanitation (p = 0.2485 > α (0.05)) with nutritional status. Conclusion: The absence of significant relationships that was found in this study was due to the presence of other complex variables related to nutritional status. ABSTRAK Latar belakang : Permasalahan gizi pada balita masih menjadi masalah yang signifikan baik pada skala global maupun lokal. Pemantauan intensif terhadap status gizi serta pengendalian berbagai faktor yang berhubungan dengan status gizi merupakan hal yang sangat penting untuk dilakukan terutama pada periode kritis yaitu sebelum anak berusia dua tahun (Baduta). Tujuan : Menganalisis hubungan kebiasaan cuci tangan ibu/pengasuh utama dan sanitasi dasar rumah dengan status gizi pada Toddlerdi Desa Mojosari, Bojonegoro. Metode : Penelitian ini adalah deskriptif analitik dengan desain cross sectional yang sasarannya adalah seluruh populasi Toddleryang memenuhi kriteria inklusi dan eksklusi. Pengumpulan data dilakukan dengan kuesioner dan observasi. Analisis hubungan dilakukan dengan uji fisher exact. Hasil : Penelitiaan ini tidak menemukan adanya hubungan yang signifikan antara kebiasaan cuci tangan (p =1 > α (0,05)) dan sanitasi dasar rumah (p = 0,2485 > α (0,05)) dengan status gizi. Kesimpulan : Tidak adanya hubungan yang ditemukan pada penelitian dikarenakan adanya variabel kompleks lainnya yang berhubungan dengan status gizi.
Targeting Nuclear Receptors for TH17-Mediated Inflammation: REV-ERBerations of Circadian Rhythm and Metabolism
Authors: Mosure Sarah A. , Wilson Adrianna N. , Solt Laura A. 
Published: March 2022

Abstract
Since their discovery, a significant amount of progress has been made understanding T helper 17 (TH17) cells' roles in immune homeostasis and disease. Outside of classical cytokine signaling, environmental and cellular intrinsic factors, including metabolism, have proven to be critical for non-pathogenic vs pathogenic TH17 cell development, clearance of infections, and disease. The nuclear receptor RORγt has been identified as a key regulator of TH17-mediated inflammation. Nuclear receptors regulate a variety of physiological processes, ranging from reproduction to the circadian rhythm, immunity to metabolism. Outside of RORγt, the roles of other nuclear receptors in TH17-mediated immunity are not as well established. In this mini-review we describe recent studies that revealed a role for a different member of the nuclear receptor superfamily, REV-ERBα, in the regulation of TH17 cells and autoimmunity. We highlight similarities and differences between reports, potential roles beyond TH17-mediated cytokine regulation, unresolved questions in the field, as well as the translational potential of targeting REV-ERBα.
Prognostic significance of microcalcifications in breast cancer (literature review)
Authors: Aksenenko V. O. , Frolova I. G. , Garbukov E. Yu. , Grigoryev E. G. , Ramazanova M. P. , Usynin E. A. , Vtorushin S. V. , Alaichiev N. A. 
Published: March 2022

Abstract. Breast cancer is one of the most commonly diagnosed cancers worldwide. According to the World Health Organization, the incidence of breast cancer was 2.26 million in 2020, overtaking the incidence of lung cancer. In Russian Federation, the increase in new cases of breast cancer over the ten years from 2005 to 2015 was 31.76 %. Microscopic calcium deposits within breast tissue, microcalcifications, can be early signs of breast cancer. Being a significant diagnostic finding, microcalcifications allow the assessment of the extent of the disease. A detailed understanding of the morphogenesis of microcalcifications can improve knowledge about early stages of breast cancer, but there is no studies that would combine the results of the latest basic scientific research and current knowledge about their clinical significance.The aim of the study was to analyze and summarize the available data on the prognostic value of microcalcifications in patients with breast cancer.Material and Methods. A search was carried out for available literary sources published in the Medline, Elibrary, etc. databases for the period since 2015. A total of 250 sources devoted to the analysis of the morphogenesis of microcalcifications and their diagnostic value were found. Of them, 37 were included in this review.
Clinical case of torpid course of metastatic triple negative breast cancer
Authors: Kulikov E. P. , Golovkin E. Yu. , Mertsalov S. A. , Vinogradov I. I. , Borisova M. V. , Vagapova S. Kh. 
Published: March 2022

Background.Breast cancer is the most common cancer and the leading cause of cancer death in women worldwide. The presence of an unfavorable molecular biological subtype significantly worsens the prognosis, making it necessary to individualize treatment strategy for each patient.The aim of the studywas to demonstrate the achievement of long-term remission in the treatment of metastatic triple-negative breast cancer. Case description. A 42-year-old patient presented to Ryazan Oncologic Dispensary in October 2006 with complaints of lump in her left breast. She was diagnosed with stage cT2N0M0 triple-negative carcinoma of the left breast. She underwent radical mastectomy for left breast cancer (October, 2006). Disease progression (metastases to lungs and mediastinal lymph nodes) occurred in June 2009. The patient received 6 courses of polychemotherapy according to the FAC regimen with a favorable response. In February 2011, the patient was found to have metastatic lesion in the brain, which was surgically removed in March, 2011. She received metronome chemotherapy. Recurrence of brain metastasis occurred 6 months after chemotherapy. The patient received external beam radiation therapy, which resulted in tumor regression, and metronomic chemotherapy was continued with a positive effect. The patient was followed up for 6 years with no evidence of disease progression. In July 2019, the follow-up examination revealed stage cT2N0M0 triple-negative cancer in the right breast. The patient underwent radical mastectomy for the right breast and 8 courses of adjuvant polychemotherapy (4 courses of AC + 4 courses of paclitaxel). The patient is alive with no signs of disease progression.Conclusion.This clinical case demonstrated personalized approach to the treatment of patients with triple-negative breast cancer. Fifteen years had passed since the detection of the primary tumor. During this time, the disease progressed three times, and breast cancer was diagnosed on the opposite side. Combined modality treatment including chemotherapy, surgery and radiotherapy allowed satisfactory results to be achieved. The patient is still alive with no signs of disease progression.
Proton therapy in the treatment of diffuse astrocytoma of the brain stem. Case report
Authors: Kireeva T. A. , Gumenetskaya Yu. V. , Gogolin D. V. , Gordon K. B. , Gulidov I. A. , Lepilina O. G. 
Published: March 2022

Background. Despite the fact that cerebral astrocytoma belongs to low-grade tumors (grade II gliomas), it often leads to disability and death of patients. The localization of the tumor determines the severity of the clinical symptoms of the disease, which significantly affects its prognosis. The choice of the optimal treatment strategy for astrocytoma localized in the brain stem poses challenges and enables the vast majority of patients to be classified as inoperable. Therefore, radiation therapy or chemoradiotherapy are the main treatment modalities for patients with low-grade glioma. The location of the tumor in close proximity to vital centers makes radiation therapy planning difficult., because the delivery of high doses of radiation can cause serious treatment complications.Description of the clinical case. We present a clinical case of a successful treatment of a young, 20-year-old male patient with diffuse astrocytoma of the brain stem. As radical surgery was impossible to be performed, the patient was offered radiation therapy. The morphology, size, and location of the primary tumor posed challenges for selecting an optimal treatment strategy due to a high risk of damage to vital centers, which could lead to disability and even death of the patient. The use of proton therapy made it possible to deliver the maximum allowable dose of radiation to the tumor, limiting radiation exposure to surrounding healthy tissues. The patient received the complete course of proton therapy. After 36 months of follow-up, no complications and signs of disease progression were found.Conclusion. Despite the high risk of treatment complications, the use of proton therapy made it possible to complete the planned course of treatment, achieve tumor stabilization and significantly improve the life quality of the patient.
Intraoperative radiotherapy with a photonic radiosurgical system in the treatment of locally advanced rectal cancer
Authors: Potemin S. N. , Uvarov I. B. , Potemin D. S. 
Published: March 2022

Aim of the study: to evaluate the results of using intraoperative radiotherapy (IO RT) in patients with locally advanced rectal cancer (RC).Material and Methods. A total of 172 patients with histologically confirmed stage II –III (pT3–4 or pN+) RC were included in this retrospective analysis; of those, 92 (53,5 %) were treated with IO RT alone and 80 (46,5 %) received both neoadjuvant EBRT and IO RT. The median follow-up was 25 months for the IO RT group and 22 months for the EBRT/IO RT group (p=0,52).Results. The incidence of toxicity was low in both groups with an overall complication rate of 5,4 %. There were no statistically significant differences between both groups in 4-year overall survival rates (59,1 % in the IO RT group versus 67,4 % in the EBRT / IO RT group, p=0,66), progression-free survival (53,6 versus 55,1 %, p=0,51) and local progression free survival (59,4 versus 65,4 %, p=0,70).Conclusion. IO RT for locally advanced RC is a safe method that ensures adequate local control and can be considered as an effective treatment method both in an isolated version and in integration into a multimodal treatment algorithm in a specialized oncological clinics.
Estimation of the feasibility of using empirical models for prediction of the second metachronous tumor after chemotherapy of the first tumor to improve cancer surveillance
Authors: Shunko E. L. , Vazhenin A. V. , Shanazarov N. A. 
Published: March 2022

Aim. To assess the possibility of using empirical models for predicting a second metachronous tumor after chemotherapy of the first one to improve the efficiency of prophylactic medical examination of cancer patients.Material and Мethods. The objects of the study are electronic databases on the chemotherapy treatment of cancer patients, extracts from the database on the treatment of patients with PM oncology for the period 1990–2015, case histories and medical records of 796 patients with metachronous PM oncology: experimental group – 496 patients after chemotherapy, control group – 300 patients after surgical treatment of the first tumor, the sample size was not previously calculated.Results. Empirical models for predicting a second metachronous tumor after chemotherapy of the first one showed the highest probability of a second metachronous tumor in three time intervals: 1256.00–1884.00 days (3.44–5.16 years; HR=2.25; tumor is 69.2 %), 3768.00–4396.00 days (10.32–12.04 years; HR=3.86; chance 79.4 %), 6280.00–6908.00 days (17, 21–18.93 years; HR=2.00; 66.7 % chance.Conclusion. Based on the results of the analysis of empirical risk models for a second metachronous tumor after chemotherapy of the first one, amendments were developed to the timing of dispensary observation of patients with primary multiple metachronous malignant neoplasms after chemotherapy of the first tumor. Knowledge of the most probable timing of the occurrence of a second metachronous tumor after chemotherapy of the first one makes it possible to more accurately draw up and, if necessary, adjust the plan for dispensary observation after chemotherapy treatment of the first tumor.
Ekoteologia prawosławna w ujęciu “zielonego patriarchy” Bartłomieja I
Authors: Leonkiewicz Łukasz 
Published: March 2022

Przez ostatnie trzydzieści lat patriarcha Bartłomiej I dążył do wypracowania w świadomości prawosławnej wrażliwości na kwestie ochrony środowiska naturalnego. Liczne przygotowane przez niego inicjatywy doprowadziły do tego, że temat ten zaistniał na stałe w refleksji teologicznej, w kalendarzu liturgicznym, w modlitwach mnichów i wiernych Kościoła prawosławnego. Związani z patriarchatem konstantynopolitańskim działacze prawosławni propagują ideę ochrony środowiska, wcielają ją w życie, dając przykład innym środowiskom prawosławnym. Z pewnością nie jest to kwestia zakończona. Patriarcha Bartłomiej wciąż na nowo podejmuje działania na rzecz ekologii, głosi stale potrzebę uwrażliwienia się na świat natury i podjęcie działań w celu ochronienia go. Swoją działalnością rozpoczął bardzo współczesną aktywność Kościoła prawosławnego, pokazując, że teologia może i powinna podejmować kwestie współczesne. Rozświetlanie współczesnych problemów tradycją patrystyczną może doprowadzić do odświeżenia współczesnej dyskusji teologicznej i ożywienia jej w kontekście nowych wyzwań, jakie stoją przed Kościołem prawosławnym w XXI wieku. Dzięki jego aktywności na polu ekoteologii następne pokolenia ludzi Kościoła będą mogły korzystać z tego, co zostało już wypracowane, będą mogły rozwijać zagadnienia dotychczas nie podjęte i rozpocząć współpracę międzywyznaniową na rzecz budowania wrażliwości ekologicznej w Kościele. Najlepszym przykładem takiej działalności jest encyklika papieża Franciszka “Laudato Si”, w której wspominane jest nauczanie patriarchy Bartłomieja I o “konieczności wyrażenia skruchy z powodu braku naszej dbałości o planetę”[1]. Pozostaje jedynie mieć nadzieję, że przyszłe pokolenia będą czerpały z dziedzictwa, jakie patriarcha Bartłomiej wypracował przez ostatnie trzydzieści lat.

[1] Encyklika Laudato Si’ Ojca Świętego Franciszka poświęcona trosce o wspólny dom, 24.05.2015, online: https://www.vatican.va/content/francesco/pl/encyclicals/documents/papa-francesco_20150524_enciclica-laudato-si.html, dostęp: 11.06.2021.