bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interrupting Biases in the Experience and Management of Pain
Authors: Booker Staja Q. , Baker Tamara A. , Epps Fayron , Herr Keela A. , Young Heather M. , Fishman Scott 
Published: August 2022

This article is part of a series, Supporting Family Caregivers: No Longer Home Alone, published in collaboration with the AARP Public Policy Institute. Results of focus groups, conducted as part of the AARP Public Policy Institute's No Longer Home Alone video project, supported evidence that family caregivers aren't given the information they need to manage the complex care regimens of family members. This series of articles and accompanying videos aims to help nurses provide caregivers with the tools they need to manage their family member's health care at home.
The articles in this new installment of the series provide practical information nurses can share with family caregivers of persons living with pain. To use this series, nurses should read the articles first, so they understand how best to help family caregivers. Then they can refer caregivers to the informational tear sheet—Information for Family Caregivers—and instructional videos, encouraging them to ask questions. For additional information, see Resources for Nurses.
Improving Student Perceptions of Simulation Effectiveness With Co-Facilitation From Prebriefing Through Debriefing
Authors: de Rosa Cristina , Frost Erica , Ziegler Erin , Spies Martha 
Published: August 2022

Abstract
Co-facilitation (combining presence and expertise of clinical faculty and simulationists during all stages of simulation) presents an opportunity to improve student perceptions of effectiveness. Using a retrospective before and after comparison, data on students’ perceptions were collected from baccalaureate nursing students in clinical courses after each simulation experience. Mean differences in Simulation Effectiveness Tool-Modified scores for pre- and post-implementation were compared, as well as scores between levels of students. Statistically significant improvements in student-rated simulation effectiveness were found with co-facilitation. The authors recommend future studies expanding this methodology and considering co-facilitation where feasible.
End-of-Semester Report-Out: A Curriculum Evaluation Strategy
Authors: Lanz Amelia S. , Adams Marsha Howell , Frith Karen H. 
Published: August 2022

Abstract
An end-of-semester course -reporting strategy serves as one component of an overall curriculum evaluation plan. A framework specifying reporting criteria is used to guide the process. Report elements include integration of concepts in clinical, descriptions of active classroom learning strategies, testing data on concept performance, and exam statistics. Grade distribution and standardized testing scores are also reported. The report-out strategy has helped identify curricular strengths and weaknesses, encouraged instructional collaboration among faculty, informed decision-making, and contributed significantly to a successful curriculum transformation. The strategy has supported improved program outcomes in standardized testing scores and licensure pass rates.
A Systematic Approach to Nursing Curriculum Review Made Easier
Authors: Trent Peggy 
Published: August 2022

Abstract
The Nursing Curriculum Committee has a critical role in improving the quality of nursing programs and ensuring that standards from accreditation agencies and professional organizations are met. The work of the committee also presents opportunities for faculty to confirm that programs meet the needs of the community and address current trends. A systematic schedule for review helps with organization and ensures that all courses and programs are reviewed. Developing a systematic approach and sharing this information with faculty allows for a transparent method of reviewing courses and programs, as well as preparing faculty for their role in this process.
Factors Associated With Perioperative Hospital Acquired Pressure Injury in Patients Undergoing Spine Surgery in the Prone Position: A Prospective Observational Study
Authors: Choi Seungeun , Kim Yoon Jung , Oh Hyongmin , Yuh Woon Tak , Lee Chang-Hyun , Yang Seung Heon , Kim Chi Heon , Chung Chun Kee , Park Hee-Pyoung 
Published: August 2022

Background:
Hospital acquired pressure injury (HAPI) is associated with poor clinical outcomes and high medical costs. Patients undergoing surgery in the prone position are particularly vulnerable to perioperative HAPI. This prospective observational study investigated the factors associated with HAPI in patients undergoing elective spine surgery in the prone position.

Methods:
Two hundred eighty-seven patients undergoing elective spine surgery participated in this study. Demographics, perioperative vital signs, laboratory findings, surgical data, and intraoperative data were prospectively recorded. The sites and stages of HAPI were investigated on postoperative day 2. The stages of HAPI were evaluated using the pressure injury staging system of the National Pressure Ulcer Advisory Panel.

Results:
Perioperative HAPI was observed in 71 (24.7%) patients (stage 1, 40; stage 2, 31). The most frequent site (number) of HAPI was the upper extremities (33), followed by the chest (32), lower extremities (20), face (18), pelvis (10), and abdomen (9). In multivariate analysis, the duration of prone positioning per hour (odds ratio [95% confidence interval], 1.48 [1.25-1.74]; P<0.001) and intraoperative pH ≤7.35 (1.98 [1.05-3.76]; P=0.036) were associated with perioperative HAPI.

Conclusions:
The incidence of perioperative HAPI was 24.7% in patients undergoing elective spine surgery in the prone position. Long duration of prone positioning and intraoperative acidosis were associated with increased development of perioperative HAPI.
Predicting Aided Outcome With Aided Word Recognition Scores Measured With Linear Amplification at Above-conversational Levels
Authors: Fereczkowski Michal , Neher Tobias 
Published: August 2022

Objectives:
Many hearing aid (HA) users receive limited benefit from amplification, especially when trying to understand speech in noise, and they often report hearing-related residual activity limitations. Current HA fitting strategies are typically based on pure-tone hearing thresholds only, even though suprathreshold factors have been linked to aided outcomes. Furthermore, clinical measures of speech perception such as word recognition scores (WRSs) are performed without frequency-specific amplification, likely resulting in suboptimal speech audibility and thus inaccurate estimates of suprathreshold hearing abilities. Corresponding measures with frequency-specific amplification (“aided”) would likely improve such estimates and enable more accurate aided outcome prediction. Here, we investigated potential links between either unaided WRSs or aided WRSs measured at several above-conversational levels and two established HA outcome measures: The Hearing-In-Noise Test (HINT) and the International Outcome Inventory for Hearing Aids (IOI-HA).

Design:
Thirty-seven older individuals with bilateral hearing impairments participated. Two conditions were tested: unaided and aided, with all stimuli presented over headphones. In the unaided condition, the most comfortable level (MCL) for the presented speech stimuli, WRS at MCL+10 dB as well as uncomfortable levels (UCLs) for narrowband noise stimuli were measured. In the aided condition, all stimuli were individually amplified according to the “National Acoustic Laboratories—Revised, Profound” fitting rule. Aided WRSs were then measured using an Interacoustics Affinity system at three above-conversational levels, allowing for the maximum aided WRS as well as the presence of “rollover” in the performance-intensity function to be estimated. Multivariate data analyses were performed to examine the relations between the HINT (measured using a simulated HA with the NAL-RP amplification) or IOI-HA scores (for the participants’ own HAs) and various potential predictors (age, pure-tone average hearing loss, unaided WRS, aided WRS, rollover presence [ROp], and UCL).

Results:
Aided WRSs predicted the HINT scores better than any other predictor and were also the only significant predictor of the IOI-HA scores. In addition, UCL and ROp in the aided WRSs were significant predictors of the HINT scores and competed for variance in the statistical models. Neither age nor pure-tone average hearing loss could predict the two aided outcomes.

Conclusions:
Aided WRSs can predict HA outcome more effectively than unaided WRSs, age or pure-tone audiometry and could be relatively easily implemented in clinical settings. More research is necessary to better understand the relations between ROp, UCL and speech recognition at above-conversational levels.
Trends in Outcomes of a Prospective Consecutively Enrolled Single-Center Adult Cervical Deformity Series
Authors: Passias Peter G. , Passfall Lara , Imbo Bailey , Williamson Tyler , Joujon-Roche Rachel , Krol Oscar , Tretiakov Peter , Kummer Nicholas A. , Lanre-Amos Tomi , Schoenfeld Andrew J. , De La Garza Rafael , Janjua Muhammad Burhan , Sagoo Navraj , Vira Shaleen , Diebo Bassel , Lafage Renaud , Protopsaltis Themistocles , Lafage Virginie 
Published: August 2022

Study Design.
Retrospective cohort.

Objective.
To describe the 2-year outcomes for patients undergoing surgical correction of cervical deformity.

Background.
Adult cervical deformity (CD) has been shown to compromise health-related quality of life. While advances in spinal realignment have shown promising short-term clinical results in this parameter, the long-term outcomes of CD corrective surgery remain unclear.

Methods.
Operative CD patients >18 years with 2-year (2Y) HRQL/radiographic data were included. Improvement in radiographic, neurologic and HRQL outcomes were reported. Patients with a prior cervical fusion and patients with the greatest and smallest change based on NDI, NRS neck, mJOA were compared using multivariable analysis controlling for age, and frailty, and invasiveness.

Results.
158 patients were included in this study. By 2Y, 96.3% of patients improved in Ames cSVA modifier, 34.2% in TS-CL, 42.0% in Horizontal gaze modifier, and 40.9% in SVA modifier. Additionally, 65.5% of patients improved in Passias CL modifier, 53.3% in TS-CL modifier, 100% in C2-T3 modifier, 88.9% in C2S modifier, and 81.0% in MGS modifier severity by 2Y. The cohort significantly improved from BL to 2Y in NDI, NRS Neck, and mJOA, all P<0.05. 59.3% of patients met MCID for NDI, 62.3% for NRS Neck, and 37.3% for mJOA. 97 patients presented with at least one neurologic deficit at BL and 63.9% no longer reported that deficit at follow-up. There were 45 (34.6%) cases of DJK (∆DJKA>10° between LIV and LIV-2), of which 17 were distal junctional failure (DJF−DJK requiring reoperation). Patients with the greatest beneficial change were less likely to have had a complication in the 2-year follow-up period.

Conclusion.
Correction of cervical deformity results in notable clinical and radiographic improvement with most patients achieving favorable outcomes after two years. However, complications including distal junctional kyphosis or failure remain prevalent.
Wide Spectrum of Cardiac Phenotype in Myofibrillar Myopathy Associated With a Bcl-2-Associated Athanogene 3 Mutation: A Case Report and Literature Review
Authors: Akaba Yuichi , Takeguchi Ryo , Tanaka Ryosuke , Makita Yoshio , Kimura Takashi , Yanagi Kumiko , Kaname Tadashi , Nishino Ichizo , Takahashi Satoru 
Published: August 2022

Abstract
Myofibrillar myopathy is a clinically and genetically heterogeneous group of muscle disorders characterized by myofibrillar degeneration. Bcl-2-associated athanogene 3 (BAG3)-related myopathy is the rarest form of myofibrillar myopathy. Patients with BAG3-related myopathy present with early-onset and progressive muscle weakness, rigid spine, respiratory insufficiency, and cardiomyopathy. Notably, the heterozygous mutation (Pro209Leu) in BAG3 is commonly associated with rapidly progressive cardiomyopathy in childhood. We describe a male patient with the BAG3 (Pro209Leu) mutation. The patient presented at age 7 years with muscle weakness predominantly in the proximal lower limbs. Histologic findings revealed a mixture of severe neurogenic and myogenic changes. His motor symptoms progressed rapidly in the next decade, becoming wheelchair-dependent by age 17 years; however, at the age of 19 years, cardiomyopathy was not evident. This study reports a case of BAG3-related myopathy without cardiac involvement and further confirmed the wide phenotypic spectrum of BAG3-related myopathy.
Patient-Reported Symptom Burden of Charcot–Marie–Tooth Disease Type 1A: Findings From an Observational Digital Lifestyle Study
Authors: Thomas Florian P. , Saporta Mario A. , Attarian Shahram , Sevilla Teresa , Sivera Rafael , Fabrizi Gian M. , Genovese Filippo , Gray Amy J. , Bull Simon , Tanesse Daniel , Rego Manuel , Moore Allison , Hollett Courtney , Paoli Xavier , Sénéchal Thomas , Day Laura , Ouyang Chengyu , Llewellyn Samuel , Larkin Mark , Boutalbi Youcef 
Published: August 2022

Abstract

Objectives:
This study aims to explore the impact of Charcot–Marie–Tooth disease type 1A (CMT1A) and its treatment on patients in European (France, Germany, Italy, Spain, and the United Kingdom) and US real-world practice.

Methods:
Adults with CMT1A (n = 937) were recruited to an ongoing observational study exploring the impact of CMT. Data were collected via CMT&Me, an app through which participants completed patient-reported outcome measures.

Results:
Symptoms ranked with highest importance were weakness in the extremities, difficulty in walking, and fatigue. Almost half of participants experienced a worsening of symptom severity since diagnosis. Anxiety and depression were each reported by over one-third of participants. Use of rehabilitative interventions, medications, and orthotics/walking aids was high.

Conclusions:
Patient-reported burden of CMT1A is high, influenced by difficulties in using limbs, fatigue, pain, and impaired quality of life. Burden severity appears to differ across the population, possibly driven by differences in rehabilitative and prescription-based interventions, and country-specific health care variability.
Iodine-125 plaque brachytherapy for diffuse choroidal hemangioma
Authors: Azarcon Corrina P. , Qiu Richard L.J. , Sobol Ethan K. , Hubbard G. Baker , Craven Caroline M. , Bergstrom Chris S. , Wells Jill R. 
Published: August 2022

Abstract

Purpose:
To report 6 cases of diffuse choroidal hemangioma (DCH) in children treated with iodine-125 plaque brachytherapy at a single tertiary care center.

Methods:
Retrospective case series.

Results:
Six pediatric patients diagnosed with DCH were included in the study. Pre-plaque visual acuity (VA) ranged from 20/150 to no light perception (NLP). All patients had extensive serous retinal detachment at presentation. An iodine-125 radioactive plaque was placed on the affected eye to administer a dose of 34.2-42.1 Gy to the tumor apex over a median of 4 days. Tumor regression and subretinal fluid resolution were observed in all eyes within 17 months of treatment. Visual acuity improved in 2 patients. Radiation-induced cataract and subretinal fibrosis were documented in 1 case, and 1 patient developed radiation retinopathy. No patients developed neovascular glaucoma within a follow-up range of 12-65 months.

Conclusion:
Iodine-125 plaque radiotherapy is an effective option for DCH, although there is a risk for radiation-induced complications.
CENTRAL RETINAL VEIN OCCLUSION ASSOCIATED WITH USE OF AMYL NITRITE “POPPERS”
Authors: Lam Andrew , Gulati Shilpa , Foster Bradley S. , Lally David R. 
Published: August 2022

Purpose:
To report a case of central retinal vein occlusion in a young patient after the use of amyl nitrate “poppers.”

Methods:
Description of the patient's clinical history, ophthalmic examination, retinal imaging, and treatment.

Results:
A 38-year-old man presented with a central retinal vein occlusion in his right eye after inhaling amyl nitrite “poppers.” There appeared to be a definitive temporal association between poppers use and both the onset of the vein occlusion and the patient's visual scotomata, which recurred immediately after drug use multiple times. Optical coherence tomography displayed cystic macular edema, which was treated with intravitreal bevacizumab. The patient's hypercoagulable laboratory workup was negative.

Conclusion:
This is the first report of a central retinal vein occlusion associated with poppers inhalation. A high index of suspicion for poppers use should be maintained in young patients who present with retinal vein occlusion, particularly in homosexual patients with a normal laboratory workup that fails to reveal a hypercoagulable etiology.
Paracentral Acute Middle Maculopathy with Sickle Cell Trait
Authors: Baker Mikayla , Neuhouser Adam , Nazari Hossein 
Published: August 2022

ABSTRACT

Purpose:
To report a case of paracentral acute middle maculopathy in a pediatric patient with sickle cell trait.

Methods:
The patient was evaluated with a comprehensive ophthalmic examination, optical coherence tomography (OCT), optical coherence tomography angiography, and fluorescein angiography.

Results:
Acute loss of vision occurred immediately after an uneventful scleral buckling procedure for retinal detachment in a 16-year-old female. Retinal imaging studies confirmed the occurrence of paracentral acute middle maculopathy (PAMM), an ischemic condition characterized by infarction of the inner nuclear layer of the retina caused by hypoperfusion of the intermediate and deep capillary plexuses. Laboratory evaluation was only remarkable for sickle cell trait. Over a course of 3 months after the loss of vision, visual acuity improved from 20/1000 to 20/20, and OCT lesion resolved to a parafoveal area of inner and middle retinal layer thinning. Paracentral scotoma corresponding to the atrophic area persisted.

Conclusion:
Dehydration due to the presurgical non-per-os (NPO) status and transient increase in intraocular pressure during the buckling surgery may have predisposed this patient with sickle cell trait to a sickling event that caused localized ischemia in the middle retina’s end-capillaries. Avoiding long NPO status, being mindful of transient intraocular pressure elevation during scleral buckling procedures, and presurgical hemoglobin electrophoresis in at-risk populations are recommended to prevent sickling attacks during retinal surgeries in individuals with sickle cell trait.
The value of the SUV ratio between lymph node and bone marrow in predicting pelvic lymphatic metastasis of patients with locally advanced cervical cancer: an integrated PET/CT study
Authors: Liu Ying , Hua Jun , Liu Lisheng , Zhang Wei , Xu Shufan , Chen Xiaoliang 
Published: August 2022

Purpose
This study aimed to evaluate the value of the standardized uptake value (SUV) ratio between lymph nodes and bone marrow (BM) measured by Fluorine-18-fluorodeoxyglucose PET and computed tomography (18F-FDG PET/CT) for predicting pelvic lymph node (PLN) metastasis in patients with locally advanced cervical cancer (LACC).

Materials and methods
A total of 62 patients with pathological stage Ib-IVa cervical cancer who underwent 18F-FDG PET/CT before treatment were reviewed retrospectively. We measured the metabolic and morphological parameters of lymph nodes and primary tumors, bone marrow SUV (SUVBM) and calculated the ratio of lymph nodes maximum SUV (SUVmax) to bone marrow SUV (SUVLN/BM) and the ratio of short-axis diameter to long-axis diameter (Ds/l) of lymph nodes. A receiver operating characteristic (ROC) curve was performed to evaluate the diagnostic efficacy of each parameter.

Results
There were 180 lymph nodes with pathological evidence included in the study. Our results indicated that Ds/l, SUVmax of lymph nodes (SUVLN) and SUVLN/BM were independent risk factors for PLN metastasis in LACC (P < 0.05), and SUVLN/BM showed the best diagnostic performance by ROC curve analysis. The SUVBM in the anemia group was significantly higher than that in the nonanemia group (3.05 vs. 2.40, P < 0.05); furthermore, false-positive cases decreased when the SUVLN/BM was used as the diagnostic criterion instead of SUVLN, especially in the anemia group. ROC curve analysis showed that the area under the curve value of the combination of SUVLN/BM and Ds/l was 0.884 (P < 0.05), which was higher than Ds/l or SUVLN/BM alone.

Conclusions
SUVLN/BM could improve the ability to predicting PLN metastasis in patients with LACC, and the diagnostic efficacy of the combination of SUVLN/BM and Ds/l might be better than that of a single parameter.
The posterior tibial artery free flap for head and neck reconstruction
Authors: Kejner Alexandra E. 
Published: August 2022

Purpose
The posterior tibial artery free flap (PTAFF) has been a mainstay of lower extremity reconstruction. Over the past 30 years, it has been intermittently used for head and neck reconstruction with recent renewed interest given its versatility.

Recent findings
Use of the PTAFF in head and neck reconstruction is expanding along with the continued evolution of microvascular techniques. Differences in overall health, incidence of smoking, and body habitus can impact the utility of this flap and should be taken into consideration when choosing to use it.

Summary
The PTAFF for head and neck reconstruction is a useful tool for the head and neck/reconstructive surgeon. Understanding the potential pitfalls and caveats to use of the PTAFF is important for successful use of this versatile flap.
Where Are the Questions About Firearms?
Authors: Donelan Karen , Guzikowski Sophia , Buonomo Giancarlo , Galls Alexandra , Sacks Chana A. , Masiakos Peter T. 
Published: August 2022

Objective:
To evaluate existing federal survey data infrastructure pertaining to firearms and firearm-related violence.

Background:
Firearm-related violence results in >40,000 deaths in the United States each year. Limited federal investments over the past 25 years have restricted a systematic approach to federal data collection related to firearms.

Methods:
We conducted a systematized review of the 22 continuously administered public health surveys in the US Federal Statistical System conducted between 1995 and 2020. Surveys were included if they addressed 1 of 4 areas of inquiry: (1) firearms; (2) exposure to or experience of firearm-related, intimate partner, or other interpersonal violence; (3) substance use and substance use disorder; (4) behavioral health. Descriptive statistics were used to report the frequency of relevant questions.

Results:
Nine of 22 surveys were focused on one of these domains and included in this analysis, 7 focused on adults (total 128 survey administrations over the study period) and 2 on youth and adolescents (total 30 administrations). Among all adult surveys, questions related to firearm use were asked 20% of the time, firearm-related violence 4%, firearm ownership 23%; in youth surveys, firearm use was addressed 0 times, firearm-related violence 57%, and firearm ownership 90%.

Conclusions:
Reliable national data are critical to understanding firearm-related violence as well as to developing, implementing, and evaluating public health measures to address it. Improving the consistency of questions pertaining to firearm access and experiences of violence in federal surveys offers an opportunity to improve national data infrastructure.