bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of genetic variants of the vitamin D receptor gene with vitiligo in a tertiary care center in a Saudi population: a case-control study
Authors: Saif Ghada Bin , Khan Imran Ali 
Published: April 2022

BACKGROUND:

Vitiligo is a common cutaneous disorder of the skin and hair caused by a systemic depigmentation disorder that affects 1% of the population or less due to its onset in early adulthood. Meta-analyses have documented a linkage between vitiligo and the vitamin D receptor (
VDR
) gene.

OBJECTIVE:

Investigate the relationship between the ApaI, BsmI, FokI and TaqI genetic variants in the
VDR
gene with vitiligo in a Saudi population.

DESIGN:
Case-control.

SETTING:
Single tertiary care center.

PATIENT AND METHODS:

The case-control study was carried out between January 2015-December 2015 in Saudi vitiligo patients and healthy controls.
VDR
genetic variants or polymorphisms (ApaI, BsmI, FokI and TaqI) were genotyped by polymerase chain reaction-restriction fragment length analysis followed by 3% agarose gel electrophoresis. Applicable statistical methods were used to assess relationships between vitiligo cases and controls.

MAIN OUTCOM MEASURE:
Effect of genotype distribution among four single nucleotide polymorphisms.

SAMPLE SIZE:
152 vitiligo (median [IQR] 23 [19] years) patients and 159 healthy controls (45 [28.5] years).

RESULTS:

We found an association of vitiligo with ApaI and BsmI polymorphisms (
P
<.05). However, a decreased risk was noted in vitiligo patients with FokI and TaqI polymorphisms and in the diplotype and haplotype analysis within males and females. A positive association with vitiligo was observed in ACAC and AC (adjusted by gender) haplotypes (
P
<.05). The strongest linkage disequilibrium was observed between rs79785232 (ApaI) and rs731236 (TaqI) polymorphisms (r
2
=.83), followed by rs2228570 (FokI) and rs1544410 (BsmI) polymorphisms (r
2
=.53).

CONCLUSIONS:
Our results confirm an association of vitiligo with ApaI and BsmI polymorphisms and fail to show an association in TaqI and FokI polymorphism with vitiligo. Additional studies need to be carried out in different Arab populations to determine whether the polymorphisms are present.

LIMITATIONS:
Controls not age matched, small sample size, lack of biochemical parameters.

CONFLICT OF INTEREST:
None.
Massive-Parallel Trajectory Calculations version 2.2 (MPTRAC-2.2): Lagrangian transport simulations on graphics processing units (GPUs)
Authors: Hoffmann Lars , Baumeister Paul F. , Cai Zhongyin , Clemens Jan , Griessbach Sabine , Günther Gebhard , Heng Yi , Liu Mingzhao , Haghighi Mood Kaveh , Stein Olaf , Thomas Nicole , Vogel Bärbel , Wu Xue , Zou Ling 
Published: April 2022

Abstract. Lagrangian models are fundamental tools to study atmospheric transport processes and for practical applications such as dispersion modeling for anthropogenic and natural emission sources. However, conducting large-scale Lagrangian transport simulations with millions of air parcels or more can become rather numerically costly. In this study, we assessed the potential of exploiting graphics processing units (GPUs) to accelerate Lagrangian transport simulations. We ported the Massive-Parallel Trajectory Calculations (MPTRAC) model to GPUs using the open accelerator (OpenACC) programming model. The trajectory calculations conducted within the MPTRAC model were fully ported to GPUs, i.e., except for feeding in the meteorological input data and for extracting the particle output data, the code operates entirely on the GPU devices without frequent data transfers between CPU and GPU memory. Model verification, performance analyses, and scaling tests of the Message Passing Interface (MPI) – Open Multi-Processing (OpenMP) – OpenACC hybrid parallelization of MPTRAC were conducted on the Jülich Wizard for European Leadership Science (JUWELS) Booster supercomputer operated by the Jülich Supercomputing Centre, Germany. The JUWELS Booster comprises 3744 NVIDIA A100 Tensor Core GPUs, providing a peak performance of 71.0 PFlop s−1. As of June 2021, it is the most powerful supercomputer in Europe and listed among the most energy-efficient systems internationally. For large-scale simulations comprising 108 particles driven by the European Centre for Medium-Range Weather Forecasts' fifth-generation reanalysis (ERA5), the performance evaluation showed a maximum speed-up of a factor of 16 due to the utilization of GPUs compared to CPU-only runs on the JUWELS Booster. In the large-scale GPU run, about 67 % of the runtime is spent on the physics calculations, conducted on the GPUs. Another 15 % of the runtime is required for file I/O, mostly to read the large ERA5 data set from disk. Meteorological data preprocessing on the CPUs also requires about 15 % of the runtime. Although this study identified potential for further improvements of the GPU code, we consider the MPTRAC model ready for production runs on the JUWELS Booster in its present form. The GPU code provides a much faster time to solution than the CPU code, which is particularly relevant for near-real-time applications of a Lagrangian transport model.
Detecting and characterizing simulated sea breezes over the US northeastern coast with implications for offshore wind energy
Authors: Xia Geng , Draxl Caroline , Optis Michael , Redfern Stephanie 
Published: April 2022

Abstract. With the planned construction of vast offshore wind farms along the US East Coast, identifying and understanding key coastal processes, such as sea breezes, has become a critical need for the sustainability and development of US offshore wind energy. In this study, a new two-step identification method is proposed to detect and characterize three types of sea breezes (pure, corkscrew and backdoor) over the US northeastern coast from a year-long WRF (Weather Research and Forecasting) simulation. The results suggest that the proposed detection method can identify the three different types of sea breezes in the model simulation. Key sea breeze features, such as the calm zone associated with pure sea breezes and coastal jets associated with corkscrew sea breezes, are evident in the sea breeze composite imagery. In addition, the simulated sea breeze events indicate a seasonal transition from pure to corkscrew sea breeze between March and August as the land–sea thermal contrast increases. Furthermore, the location and extension of the sea breeze front are different for each type of sea breeze, suggesting that the coastal impact of sea breeze varies with sea breeze type. From the wind energy perspective, the power production associated with a 10 MW offshore wind turbine would be approximately 3 to 4 times larger during a corkscrew sea breeze event than the other two types of sea breezes. This highlights the importance of identifying the correct type of sea breeze in numerical weather/wind energy forecasting.
ANALISIS PERMINTAAN GULA PASIR DI KOTA PALANGKARAYA
Authors: Harati Rima 
Published: April 2022

Tujuan dari penelitian ini untuk menganalisis faktor-faktor yang mempengaruhi permintaan gula pasir dan bagaimana elastisitas permintaan gula pasir di Kota Palangkaraya. Adapun penelitian ini dilaksanakan di Kota Palangkaraya pada tahun 2022 dengan menggunakan time series 2008-2020. Dengan menggunakan alat analisis regresi disimpulkan bahwa pendapatan perkapita (X2) mempunyai hubungan yang sangat signifikan dengan Permintaan gula pasir (Y) di Kota Palangkaraya Harga gula pasir (X1) signifikan. Sedangkan Jumlah penduduk (X3) tidak signifikan dengan Permintaan gula pasir (Y) di Kota Palangkaraya. Koefisien elastisitas harga gula pasir mempunyai nilai sebesar 1,956 karena nilainya > 1 maka permintaan ini bersifat elastis. Koefisien elastisitas pendapatan masyarakat mempunyai nilai elastisitas positif sebesar 5,347 maka dikatakan bahwa gula pasir merupakan barang normal dan variable jumlah penduduk mempunyai nilai elastisitas positif sebesar 0,611 yang berarti bahwa jumlah penduduk berbanding lurus dengan permintaan gula pasir. Dari penelitian ini dapat ditarik kesimpulan, bahwa permintaan gula pasir di Kota Palangkaraya selama kurun waktu 2008-2020 dipengaruhi oleh pendapatan masyarakat dan berkaitan dengan hukum permintaan.
Unge med anoreksi og deres søsken: Hvordan sykdommen påvirket dagliglivet i akuttfasen og ved oppfølging etter cirka 4,5 år
Authors: Halvorsen Inger , Rø Annika , Nilsen Jan-Vegard , Rø Øyvind 
Published: April 2022

Few studies include siblings’ experiences with anorexia nervosa (AN). Aims: Describe patients’ and siblings’ retrospective views on how AN influenced their life in the acute phase of illness and at 4.5-years follow-up. Method: 34 former patients and 13 siblings that had participated in family-based inpatient treatment for AN completed questionnaires at follow-up.
Results: Patients reported high, and siblings moderate, levels of negative influences of AN, including schoolwork, leisure, worries and conflicts in the family. The majority of siblings had been afraid their ill sibling would not recover, or die, from AN. However, most former patients and siblings replied that the illness also had provided valuable experiences. Recovery from AN at follow-up was associated with lower levels of negative influences on former patients’ and siblings’ lives.
Implications: Knowledge on patients’ and siblings’ experiences is important to improve support and help them to cope with the illness and the resulting family distress.
Keywords: anorexia nervosa, eating disorders, follow-up, siblings, influence of illness
Хозяйство казахов Нура-Ишимского междуречья XIX – начала XX в. (по остеологическим материалам зимовки Бозок II)
Authors: Шагирбаев Мамбет Сапарбекович , Ганиева Айнагуль , Сакенов Сергазы Кайырбекович 
Published: April 2022

Зимовка Бозок ІІ расположена на севере Сарыарки, между двумя крупными водоразделами: реками Нура и Ишим. Эта территория богата пастбищными угодьями и водными ресурсами, которые могут обеспечить большое количество скота. Археологическими раскопками исследована площадь 625 м2. Изучены разрушенные конструкции двух жилых домов. При строительстве жилищ использовались: глина, песок, бревна, камыш. Одним из архитектурных решений, связанных с хозяйственной деятельностью, является строительство приусадебных хозяйственных построек для скота и соединение их общим проходом. В культурном слое зимовки обнаружено 292 костей млекопитающих и одна кость птицы, среди которых 189 (65%) костей определены до вида. Большая часть остеологических материалов – это раздробленные, типичные «кухонные остатки». В результате археозоологического исследования выяснилось, что 98,5% костей происходит от домашних копытных (крупный рогатый скот, лошади, овцы). Остатки крупного рогатого скота составляют 48,1%, лошади – 39,6%, мелкого рогатого скота – 9,5%. Найдено две кости собаки и одна кость птицы, а также кости принадлежащие эмбриону или новорожденному (?) теленку. Домашних животных забивали и разделывали на территории зимовки. Примечательной особенностью является индивидуально захороненный скелет собаки, найденный в районе зимовки. В статистических исследованиях конца ХІХ – начала ХХ в. в Акмолинской области зафиксировано преобладание крупного рогатого скота (КРС). Преобладание костей КРС на зимовке косвенно подтверждает эти данные.
Üniversite Öğrencilerinin Kanser Farkındalık Düzeylerinin Belirlenmesi
Authors: YILDIZ ÇİLENGİROĞLU İrem , ÜNSAR Serap , EROL Özgül 
Published: April 2022

Amaç: Bu araştırma üniversite öğrencilerinin kanser ve belirtileri hakkındaki farkındalık düzeylerini belirlemek amacıyla planlandı.
Yöntem: Araştırma, Trakya Üniversitesi Sağlık Bilimleri Fakültesi Hemşirelik Bölümü ve İktisadi ve İdari Bilimler Fakültesi İşletme Bölümü’nde öğrenim gören 300 öğrenci ile yürütüldü. Veri toplamada araştırmacılar tarafından literatür bilgisi doğrultusunda hazırlanan sosyodemografik özellikler ve kanser hakkındaki farkındalığı değerlendirmek için kanser ile ilgili bilgiler içeren anket formu kullanıldı. p
EFFECT OF WORK ENVIRONMENT, WORK MOTIVATION AND WORK EXPERIENCE ON EMPLOYEE PERFORMANCE
Authors: Firdaus Marasahala S  
Published: April 2022

Penelitian ini bertujuan untuk menjelaskan pengaruh Lingkungan Kerja, Motivasi Kerja dan Pengalaman Kerja terhadap Kinerja Karyawan pada Sentra Industri Mikro Kecil Brem di Kabupaten Madiun. Hasil penelitian pendahuluan menunjukkan bahwa kinerja karyawan berpluktuatif (tidak stabil). Hasil penelitian Praci, (2017) menunjukkan bahwa kingkungan kerja berpengaruh positif tidak signifikan terhadap kinerja karyawan. Fauziah H (2012) menemukan bahwa motivasi kerja berpengaruh positif tidak signifikan terhadap kinerja karyawan. Temuan Kereh EM. et al (2018) bahwa pengalaman kerja berpengaruh tidak signifikan terhadap kinerja karyawan. Model penelitian dengan pengembangan hipotesis diturunkan berdasarkan pada literatur. Untuk memberikan bukti empiris, penelitian ini melakukan survey, menggunakan data primer yang dikumpulkan menggunakan daftar kuisioner, dan sampling jenuh terhadap 40 orang karyawan pada Sentra Industri Kecil Brem di Kabupaten Madiun. Hasil penelitian menunjukkan bahwa lingkungan kerja, motivasi kerja dan pengalaman kerja berpengaruh positif dan signifikan terhadap kinerja karyawan pada Sentra Industri Kecil Brem di Kabupaten Madiun. Hasil Penelitian ini tidak mendukung penelitian Praci, (2017), Fauziah H (2012) dan Kereh.E M. et al (2018). Implikasi penelitian , menguji persepsi 40 orang karyawan pada Sentra Industri Kecil Brem di Kabupaten Madiun. Teknik analisis yang digunakan adalah Regresi linera berganda.
Humic acid and potassium feldspar improve growth, yield and head quality of broccoli grown under saline water irrigation
Authors: Ibrahim Mona Adel , Merghany Merghany Mohamed , Hassan Hassan Ali , El-All Hatem Mohamed Abd , Abdelaziz Mohamed Ewis 
Published: April 2022

An open field experiment was carried out during the two successive seasons of 2018/2019 and 2019/2020 respectivly, at Badr City, El-Beheira, Egypt to study the effect of saline irrigation water on grwoth, yield and quality of broccoli (Brassica oleraceae L var. Italica) cultivar “Marathon” grown in sand soil. During soil preparation, soil was supplied with 2 ton of gypsum and 7.8 ton of compost/fed., in combination with 2 levels of potassium feldspar (141- 424 kg/fed.), to supplement sand soil with 100 and 130 unites of K2O. Three levels of humic acid (2, 4 and 6 L humic acid/fed.) were foliar sprayed after two weeks post transplanting at 10 days intervals. Plants were arranged in three replicates using randomized complete blocks design. Control was supplied with full NPK mineral fertilizers, as recommended, and irrigated with saline irrigation water. Our results show that saline water decreased growth, yield and quality of control broccoli plants in the two growing seasons. On the other hand, application of humic acid and organic soil amendments enhanced performance of broccoli plants grown under saline water.
Vertical wind shear in the lowest layers of the atmosphere over Thumba during winter months-A preliminary study
Authors: RAO M. S. V. , SIKDAR D. N. , CHANDRASEKHARAN C. K. 
Published: April 2022

Vertical wind shear in the lowest layers of the atmosphere over Tumba-an equatorial station -has been studied. Wind data from the surface up to 200 ft were collected at different altitudes (8, 31, 56, 134 and 200 ft) during the months December 1963 and January 1964, for the above study. Analysis reveals that appreciable wind shear exists very close to the surface, i,e in the layer up to 31 ft. On the other hand, in the layer 31-200 ft, the shear values are not considerable. It is further observed that the shear magnitude reaches maximum in the afternoon, The frequency of occurrence of shear magnitudes more than 10 kts/30 m (which, as indicated by ICAO, is important for supersonic transport operation) is high in the lowest layer round about l430 IST during the winter months.
Total Solar Radiation in relation to duration of sunshine
Authors: YADAV B. R. 
Published: April 2022

An attempt has been made to establish a relation between the total radiation from sun and sky and the duration of bright sunshine based On the formula., Q;Q A = a+b’n/N), Q and QA being the radiation amounts On one square centimeter of horizontal surface at the surface of the earth and at the top of .the atmosphere respectively and n and N being the actual and the maxi mum possible hours of bright sunshine respectively. The values of the regression constants a and b have been computed for daily, weekly and monthly data. Data from daily observations have been grouped for the dry and the monsoon seasons, and the constants a and b calculated and compared with those obtained by others.

Mean monthly total radiation at a few places in north India, having the same cloud regime as at Delhi, has also been computed and discussed.
Constant response sensitivity adjustments of electromagnetic seismographs
Authors: CHAUDHURY H. M. 
Published: April 2022

The conditions under which the magnification of an electromagnetic seismograph can be changed without altering its response characteristics are discussed. It is seen that. this can be done only If (I) the selsmograph lS made up of a se18mometer and galvanometer of equal free periods and (2) the dampings of the seismometer and the galvanometer are also suitably altered, When sensitivity adjustments are so made, the maximum magnification is seen to be attained when damping of the seismometer is equal to that of the galvanometer and this does not generally go with the maximum value of 11, the attenuation factor.
Stratospheric and Mesospheric Winds in July-August over an equatorial station
Authors: RAO M. S.V. , CHANDRASEKHARAN C. K. 
Published: April 2022

Three successful rocket firings were made from Thumba Equatorial Rocket Methods for Research Workers Launching Station during July-August 1964 and wind data obtained, for the first time over India, in the region 16 to 0' 3mb (~28.57 km). The winds are generally found to be east northeasterly with speed 60.90 km upto 1 mb (~ 47 km). Further above, this regime appears to terminate giving place to a complex wind pattern with considerable wind shears.

RAWIN observations of Trivanadrum and a few station in the same latitude belt on the days of firing were also collected. The combined results are examined in relation to (a) the extra biennial oscillation in the lower stratosphere and (b) the summer anticyclonic circumpolar vortex which is marked in the higher stratosphere.

Apart from the actual wind data, considerable weight is attached to the character of reflection on the radarscope as observed by the Electronics Group. This gives an indication of pronounced turbulence in summer in the equatorial stratosphere in the region 0.3 to 0.15 mb (~57-63 km).
The monsoon experiment
Authors: DAS PK 
Published: April 2022

The paper describes the observation programme of the Monsoon Experiment (MONEX) of 1979. This experiment was a sub-programme of the First GARP Global Experiment (FGGE) under the aegis of the International Council of Scientific Unions (ICSU) and the World Meteorological Organization (WMO).
A number of countries contributed to the success of the experiment. Five research ships from the USSR and three research aircraft from the USA took part, while France contributed a ship and a constant level balloon programme. India contributed four ships and one aircraft. The observation programme over the country was intensified.
Of the space based platforms, a geostationary satellite launched by the USA-GOES Indian Ocean was specially moved to cover the MONEX region. Another geostationary satellite launched by Japan provided cloud imageries for the eastern sector of the MONEX region.
The paper describes some of the prominent features of the monsoon of 1979, which were observed by this experiment. Strong temperature gradients were recorded by the Indian aircraft, and the GOES cloud vectors provided valuable data on the onset of the monsoon.
Finally, the paper describes diagnostic studies with a simple primitive equation model. Those monsoon features, which the model was able to simulate, are described, and its extension to the study of other facets of the monsoon is discussed.
Effect of Different Concentrations of Jamun and Amla Extracts to Combat Diabetes Mellitus
Authors: Ashfaq Maimoona , Imran Muhammad , Tufail Tabussam , Gilani Syed Amir , Ahmad Ishtiaque , Inayat Saima 
Published: April 2022

To compare the effect of different concentrations of jamun and amla on blood Glycemic Index of diabetes mellitus. Methodology:A total25 male Wister rats aged 10-12 weeks, weight above 150g were selected for the 2 months study. Male rats were purchased from IMBB research laboratory, The University of Lahore (UOL). During the efficacy study, streptozotocin (STZ) induced rats weredivided into five homogenous groups with 5 rats in each group. To For control group and T1, T2, T3 and T4 includes normal diet with different concentration of Jamun and Amla extracts. The change in body weight (g) and fasting blood glucose (FBG)(mg/dL) for each group of rats were monitored on every 15 days to estimate any suppressing effect of seed formulation. Results: The mean age of diabetic rats selected for study were10.61±0.493 weeks. Weight of STZ induced rats were monitored but no significant difference was shown, however mean weight of 5% Amla and 5% Jamun supplemented diet groups show an increase in mean body weight pre- and post-treatment 18.8±15.95g and 8±19.85g respectively. The minimum post-treatment FBG level of rats was noted in 5% jamun and 5% amla supplemented group with mean FBG 111.4±24mg/dL and 131.2±57.1mg/dL respectively. Conclusion:The study concluded that jamun and amla both groups show a significant reduction in fasting blood glucose level but no significant mean difference was shown in body weight gain. At the end of the study 5% amla and 5% jamun composition groups had shown significant improvement in FBG levels among diabetic induced rats.
Pengembangan Kecerdasan Spiritual Anak Sekolah Dasar
Authors: Permadi Komang Satya , Dewi Putu Yulia Angga , Sastrawan Ketut Bali , Primayana Kadek Hengki 
Published: April 2022

This research is a qualitative research. The data obtained through the interview process. The results showed that the objective of education aims to provide values and norms to an individual that will guide his behavior. However, nowadays children and adolescents are facing a problem that is called spirituality crisis. We regularly see crimes committed by them, such as; robbery, gambling, brawls between schools, murder, drug addiction and others. This is due to inexistence of balance between religiousity values in the individual itself and with the future progress that moving forward continuously. The higher IQ that people have, the more they will experts in intellectual fields, likewise EQ. It has important role in building effective human relationships. Meanwhile, SQ serves to transform spiritual values such as honesty, compassion, justice, honesty, responsibility, peace, trust and togetherness. Keywords: Spiritual Intelligence and Emotional Intelligence
QANDLI DIABETDAM QO‘LLANILADIGAN ALFA GLYUKOZIDAZANING SINTETIK VA TABIIY INGIBITORLARI
Authors: Mamatova Iroda Yusupovna , Asqarov Ibrohimjon Rahmonovich 
Published: April 2022

Ushbu makolada qandli diabetda qo‘llaniladigan alfa glyuozidaza fermentining sintetik va tabiiy ingibitorlari haqida ma’lumot keltirilgan.