bluuebunny/crossref_metadata_2025_split huggingface dataset:
Restriction of the family-centered care miracle by COVID-19: the role of the father in sleep disturbance of hospitalized pediatrics
Authors: Khaksar Sajjad , Kalhor Faramarz 
Published: November 2022

Introduction One of the important outcomes of hospitalization in infants with respiratory disease is sleep disturbance. This study was performed to investigate the role and participation of fathers in the sleep of hospitalized pediatrics with pneumonia during the COVID-19 pandemic.
Material and Methods In this clinical trial study, the parents of 40 children aged from 12 to 36 months hospitalized with a diagnosis of pneumonia were randomly assigned to the control and intervention groups. After implementing a supportive training program for the fathers in the intervention group, each father made an online video communication with the infant and the mother as the primary caregiver. Mothers completed the brief infant sleep questionnaire-revised at the beginning and a week later.
Results Data analysis showed that daytime sleep duration, setting time and total 24-hour sleep time in the intervention group improved compared to the control group. In addition, parents’ behavior toward their child’s sleep improved in the intervention group compared to the control group, but parents’ perceptions of their child’s sleep in the intervention group did not show a significant difference compared to the control group. The mean total score of the intervention group also improved compared to the control group.
Conclusion Planning to maintain family unity by educating and supporting fathers during the child’s illness and their paternal support during the COVID-19 pandemic can improve the sleep of the hospitalized child due to pneumonia.
Effect of myofunctional therapy on snoring in obese patients: a randomized trial
Authors: Sperger Thiare , Araujo Allan Cezar Faria , Soares Carolina Ferraz de Paula 
Published: November 2022

Objective To analyze the effectiveness of myofunctional therapy (MT) in the treatment of habitual snoring in obese patients.
Material and Methods This randomized clinical trial consisted of an experimental group (n=14) that underwent MT and a control group (n=26) that performed nonspecific exercises for the treatment of snoring. The Epworth sleepiness scale (ESS), Pittsburgh sleep quality index (PSQI), and short-form health survey (SF-36) were applied before and after treatment. Snoring was assessed subjectively by asking the partner about improvement after treatment. The SnoreLab app was used for objective assessment.
Results There was no significant effect of MT on any of the SnoreLab variables analyzed when groups, time points or covariates (adherence, age, body mass index [BMI], neck circumference, and sex) were compared. Neck circumference (cm) and the Pittsburgh sleep quality index score were significantly higher after treatment. There was no change in the Epworth sleepiness scale score after treatment. A correlation was found between BMI and the Pittsburgh sleep quality index and between BMI and the functional capacity component of the SF-36. Patient adherence was similar between groups.
Discussion Apps for recording snoring are a useful tool to be explored. MT exerted no significant effect on habitual snoring in obese patients despite the reduction of the snore score in the experimental group. Therapy applied without exclusion criteria based on the severity of sleep breathing disorders and pharyngeal characteristics fails to achieve the results necessary to treat habitual snoring in obese patients.
Jovens em formação profissional
Authors: Ramos Margareth Braz , Maria de Oliveira Sordillo Claudia , Maria Querido de Oliveira Chamon Edna 
Published: November 2022

Este artigo discorre sobre as representações sociais de projeto de vida elaboradas por jovens em formação profissional. A experiência com os jovens tem mostrado que, no contexto atual, estão presentes hesitações, preocupações no porvir, incertezas quanto às escolhas profissionais e ausência de rumo. O objetivo é apresentar os resultados gerados por meio da pesquisa realizada com 90 jovens entre 18 e 24 anos, oriundos de escolas públicas, que participam de um programa de capacitação e inserção profissional. A participação foi voluntária e por adesão. Para a coleta de dados, utilizou-se como instrumento um questionário do Google Forms com 12 perguntas fechadas e 3 perguntas abertas. Temas como trajetória de vida; inserção profissional e aspectos que impactaram os projetos de vida no contexto pandêmico foram tratados nesta pesquisa e serão analisados à luz da Teoria das Representações Sociais (TRS). Nos resultados apresentados, constata-se que o projeto de vida pode dar um direcionamento para a jornada da vida, e que é preciso planejar, atingir metas e ter um objetivo para ir adiante. No que se refere ao contexto pandêmico, houve uma adaptação da realidade, ao mesmo tempo em que houve um atraso no processo de aprendizagem. Os resultados revelaram a visão dos jovens em relação ao que pensam sobre os seus projetos de vida, a influência da família, amigos, escola, professores, o significado dessas relações em seu percurso profissional.
Palavras-chave: Jovem. Formação Profissional. Projeto de Vida.
Micropolitics in the Workplace among Secondary School Teachers: Causes, Consequences, and Insights
Authors: Cruz Vivian Dela , Diaz Rhey Mark 
Published: November 2022

This paper explored the experiences of teachers who have witnessed or experienced firsthand the manifestation of micropolitics in the workplace. This employed a phenomenological approach and utilized in-depth interviews to gather data on teachers' challenges, and coping, and insights and results were analyzed using thematic analysis. The findings of the study revealed that micropolitics in the workplace is prevalent. Four themes emerged in the life experiences of the teachers, namely: no freedom in the workplace; exploitation of newly-appointed teachers; favoritism in the workplace, and; affected motivation for promotion. On the other hand, results also indicated that teachers continue to thrive on working on themselves and overcoming their challenges through acceptance, self-trust, and development.
Meanwhile, the prevalence of micropolitical actions in teachers' workplaces creates an unhealthy environment and causes bias in the workplace that may cause a rise among peers. Nonetheless, the results have implications for the current system of DepEd and the local offices that handle the division. Thus, appropriate interventions must help teachers secure better-quality education for students.
Quantify total activity by volume‐of‐interest expansion with clinical SPECT/CT systems, a phantom study
Authors: Bian Junguo , James Judy R , Wagner Robert , Halama James 
Published: November 2022

AbstractPurposeQuantitative measurements of activity in SPECT are important for radioisotope therapy planning and disease diagnosis. The aim of this manuscript is to develop a robust method to quantify the total activity in a volume‐of‐interest (VOI) of different quantitative SPECT reconstructions and validate the estimation accuracy.MethodsWe customized an IEC body phantom using 3D printing technology and made six sphere inserts of 1–6 cm in diameter with at least 3 cm separation. The activity concentration within the spheres was in the range of patient lesion/organ activity. The background activity was then increased from zero to a sphere/background activity concentration of 8:1, 4:1, and 2:1. SPECT data were acquired with Philips Brightview and GE Discovery 670 SPECT/computed tomography (CT) systems under clinical acquisition protocols. Quantitative SPECT images were reconstructed with Hermes SUV‐SPECT (both Philips and GE data) and GE Q.Metrix (GE data only). The quantitative SPECT reconstructions are iterative with scatter, CT attenuation correction, and resolution recovery. We quantified the total activity by expanding the sphere VOI to include a spill‐out region. Background correction was applied by sampling a region outside the spill‐out region. The true fractions (TFs) (total activity/true activity) were measured for all six spheres for all SPECT acquisitions.ResultsThe TF is close to 100% for 2–6 cm spheres for zero background, 8:1 and 4:1 sphere/background activity ratios. The TF was found to be unreliable for the 1‐cm sphere because of the limit of phantom design. TF accuracy for 2:1 sphere/background ratio was degraded due to significantly large background, inadequate scatter correction and detector count loss.ConclusionsThe results demonstrated that the proposed quantification method is accurate for objects of different sizes in currently clinical quantitative reconstruction and has the potential for improving the accuracy for therapeutic treatment planning or radiation dosimetry calculations.
A Quantitative Investigation of Functionalized Glazing Stacks by Atom Probe Tomography
Authors: Perrin Toinin Jacques , Hatzoglou Constantinos , Voronkoff Justine , Montigaud Hervé , Guimard Denis , Wuttig Matthias , Vurpillot François , Cojocaru‐Mirédin Oana 
Published: November 2022

AbstractInsulating glazings used in products for the building and automotive market consist of flat glass with low‐emissivity (low‐E) coatings. One challenge is to increase the infrared reflectance of the glazing stack while maintaining a high transmittance. This can only be achieved if the chemical interdiffusion between the deposited layers can be controlled and characterized down to the sub‐nanometer level. For that, atom probe tomography (APT) is employed in this work; technique which allows a precise quantification of the chemical interdiffusion in 3D and down to sometimes atomic level. However, the APT specimens prepared using the standard top‐to‐down configuration are prone to systematic fracturing due to strong differences in field evaporation between the layers involved in the glazing stack. The usage of an untypical cross‐section configuration has led to improved yields, but for the latter, artifacts need to be considered and quantified. In particular, the effect of artificial layer intermixing at interfaces due to crossover is studied. It is concluded that Ni diffuses in the Ag layer via grain boundaries already in the as‐deposited state. Hence, this work opens a new perspective in terms of quantification of interdiffusion at early stages, an important finding for low‐E glass applications.
Evaluation of conservation tillage practices in the production of organic flue‐cured tobacco
Authors: Machanoff Cordelia H. , Vann Matthew Christopher , Woodley Alex L. , Suchoff David 
Published: November 2022

AbstractIntensive tillage in flue‐cured tobacco (Nicotiana tabacum L.) contributes to soil erosion and reduced water‐holding capacity of soils. Conservation tillage minimizes soil disturbance by planting a crop directly into the residue of overwintered cover crop. Reducing tillage has been shown to improve soil health (increased rainwater infiltration, improved water‐holding capacity, reduced erosion) and to reduce production costs (fuel and labor). The objective of this study was to compare the effects of conservation and conventional tillage on weed management in organically grown flue‐cured tobacco. Field studies were conducted in Kinston, NC, in 2019 and 2020 and in Rocky Mount, NC, in 2020, comparing the impacts of conventional tillage and conservation tillage on weed emergence and tobacco production. An overwintered cereal rye (Secale cereal L.) cover crop was conventionally tilled or terminated via roller‐crimper and left in place as a mulch prior to transplant of flue‐cured tobacco. Cover crop biomass, weed emergence and biomass, soil resistance, crop yield and quality, and cured leaf chemistry were evaluated. In all environments, conservation tillage with cover crop residue reduced weed density and biomass when compared with conventional tillage treatments. In 2019, cured leaf yield was higher under conservation tillage practices than under conventional tillage. In 2020, environmental conditions in both locations resulted in crop loss. These results indicate that conservation tillage practices may be an effective weed management strategy while improving yields in an organic production system. However, organic flue‐cured tobacco grown under conservation tillage is vulnerable to extreme rain events due to the exclusion of in‐season cultivation.
Spirobisnaphthalenes from Fungi, Biological activities and Total Synthesis: A Research Review
Authors: Xu Leichuan , Ma Haoyun , An Xinkun , Wang Mingan 
Published: November 2022

AbstractSpirobisnaphthalenes are a family of natural products containing two naphthalenes connected with spiroketal or dinaphthalene spiroether. This family of natural compounds has a wide range of biological activities and complex structures, and has attracted great attention from synthetic chemists in recent years. Hundreds of novel spirobisnaphthalenes have been identified from the first separation in 1989. Despite the slow pace of research in recent years, since the latest review in 2017, 30 new natural products have been isolated from the endolichenic and endophytic fungus, including Type A, B, D and E, a new special skeleton with a spiro quaternary carbon center, as well as significant breakthroughs are made in the total synthesis. Here, the last research advances in the isolation of new spirobisnaphthalenes, their activities, mode of action and the total synthesis of spirobisnaphthalenes in the last five years were afforded based on our research in this field in this review.
Kinetics Driven by Hollow Nanoreactors: An Opportunity for Controllable Catalysis
Authors: Yu Zhihao , Ji Na , Li Xiaoyun , Zhang Rui , Qiao Yina , Xiong Jian , Liu Jian , Lu Xuebin 
Published: November 2022

AbstractAs a novel class of catalytic materials, hollow nanoreactors offer new opportunities for improving catalytic performance owing to their higher controllability on molecular kinetic behavior. Nevertheless, to achieve controllable catalysis with specific purposes, the catalytic mechanism occurring inside hollow nanoreactors remains to be further understood. In this context, this Review presents a focused discussion about the basic concept of hollow nanoreactors, the underlying theory for hollow nanoreactor‐driven kinetics, and the intrinsic correlation between key structural parameters of hollow nanoreactors and molecular kinetic behaviors. We aim to provide in‐depth insights into understanding kinetics occurred within typical hollow nanoreactors. The perspectives proposed in this paper may contribute to the development of the fundamental theoretical framework of hollow nanoreactor‐driven catalysis.
Chemical Synthesis of Proteins with Base‐Labile Posttranslational Modifications Enabled by a Boc‐SPPS Based General Strategy Towards Peptide C‐Terminal Salicylaldehyde Esters
Authors: Ma Wenjie , Wu Hongxiang , Liu Sha , Wei Tongyao , Li Xiang David , Liu Han , Li Xuechen 
Published: November 2022

AbstractChemical synthesis of proteins bearing base‐labile post‐translational modifications (PTMs) is a challenging task. For instance, O‐acetylation and S‐palmitoylation PTMs cannot survive Fmoc removal conditions during Fmoc‐solid phase peptide synthesis (SPPS). In this work, we developed a new Boc‐SPPS‐based strategy for the synthesis of peptide C‐terminal salicylaldehyde (SAL) esters, which are the key reaction partner in Ser/Thr ligation and Cys/Pen ligation. The strategy utilized the semicarbazone‐modified aminomethyl (AM) resin, which could support the Boc‐SPPS and release the peptide SAL ester upon treatment with TFA/H2O and pyruvic acid. The non‐oxidative aldehyde regeneration was fully compatible with all the canonical amino acids. Armed with this strategy, we finished the syntheses of the O‐acetylated protein histone H3(S10ac, T22ac) and the hydrophobic S‐palmitoylated peptide derived from caveolin‐1.
The National Library of Medicine indexer assignment dataset: A new large‐scale dataset for reviewer assignment research
Authors: Rae Alastair R. , Mork James G. , Demner‐Fushman Dina 
Published: November 2022

AbstractMEDLINE is the National Library of Medicine's (NLM) journal citation database. It contains over 28 million references to biomedical and life science journal articles, and a key feature of the database is that all articles are indexed with NLM Medical Subject Headings (MeSH). The library employs a team of MeSH indexers, and in recent years they have been asked to index close to 1 million articles per year in order to keep MEDLINE up to date. An important part of the MEDLINE indexing process is the assignment of articles to indexers. High quality and timely indexing is only possible when articles are assigned to indexers with suitable expertise. This article introduces the NLM indexer assignment dataset: a large dataset of 4.2 million indexer article assignments for articles indexed between 2011 and 2019. The dataset is shown to be a valuable testbed for expert matching and assignment algorithms, and indexer article assignment is also found to be useful domain‐adaptive pre‐training for the closely related task of reviewer assignment.
Towards Luminescent Vanadium(II) Complexes with Slow Magnetic Relaxation and Quantum Coherence
Authors: Dorn Matthias , Hunger David , Förster Christoph , Naumann Robert , van Slageren Joris , Heinze Katja 
Published: November 2022

AbstractMolecular entities with doublet or triplet ground states find increasing interest as potential molecular quantum bits (qubits). Complexes with higher multiplicity might even function as qudits and serve to encode further quantum bits. Vanadium(II) ions in octahedral ligand fields with quartet ground states and small zero‐field splittings qualify as qubits with optical read out thanks to potentially luminescent spin‐flip states. We identified two V2+complexes [V(ddpd)2]2+with the strong field ligandN,N’‐dimethyl‐N,N’‐dipyridine‐2‐yl‐pyridine‐2,6‐diamine (ddpd) in two isomeric forms (cis‐facandmer) as suitable candidates. The energy gaps between the two lowest Kramers doublets amount to 0.2 and 0.5 cm−1allowing pulsed EPR experiments at conventional Q‐band frequencies (35 GHz). Both isomers possess spin‐lattice relaxation timesT1of around 300 μs and a phase memory timeTMof around 1 μs at 5 K. Furthermore, themerisomer displays slow magnetic relaxation in an applied field of 400 mT. While the vanadium(III) complexes [V(ddpd)2]3+are emissive in the near‐IR‐II region, the [V(ddpd)2]2+complexes are non‐luminescent due to metal‐to‐ligand charge transfer admixture to the spin‐flip states.
Long‐Wavelength Light‐Emitting Electrochemical Cells: Materials and Device Engineering
Authors: Lin Yan‐Ding , Lu Chin‐Wei , Su Hai‐Ching 
Published: November 2022

AbstractLong‐wavelength light‐emitting electrochemical cells (LECs) are potential deep‐red and near infrared light sources with solution‐processable simple device architecture, low‐voltage operation, and compatibility with inert metal electrodes. Many scientific efforts have been made to material design and device engineering of the long‐wavelength LECs over the past two decades. The materials designed the for long‐wavelength LECs cover ionic transition metal complexes, small molecules, conjugated polymers, and perovskites. On the other hand, device engineering techniques, including spectral modification by adjusting microcavity effect, light outcoupling enhancement, energy down‐conversion from color conversion layers, and adjusting intermolecular interactions, are also helpful in improving the device performance of long‐wavelength LECs. In this review, recent advances in the long‐wavelength LECs are reviewed from the viewpoints of materials and device engineering. Finally, discussions on conclusion and outlook indicate possible directions for future developments of the long‐wavelength LECs. This review would like to pave the way for the researchers to design materials and device engineering techniques for the long‐wavelength LECs in the applications of displays, bio‐imaging, telecommunication, and night‐vision displays.
Analytical enantioseparation of N‐alkyl drugs by reversed‐phase liquid chromatography with carboxymethyl‐β‐cyclodextrin as mobile phase additive
Authors: You Haibo , Chen Ben , Fang Liqun , Lin Tingting , Xu Ping , Chu Chu , Tong Shengqiang 
Published: November 2022

AbstractCarboxymethyl‐β‐cyclodextrins (CM‐β‐CDs) with five kinds of degrees of substitution were synthesized and characterized. Analytical enantioseparation of six basic drugs containing N‐alkyl groups, including pheniramine, chlorpheniramine, labetalol, propranolol, venlafaxine, and trans‐paroxol, was achieved by reversed‐phase high‐performance liquid chromatography (RP‐HPLC) using the synthesized CM‐β‐CD as chiral mobile phase additives. Key influence factors were optimized, including organic modifier, pH value, CM‐β‐CD with different degrees of substitution, and concentration of CM‐β‐CD. The mobile phase was composed of methanol and 10 mmol L−1 of phosphate buffer pH 4.0 containing 10 mmol L−1 of CM‐β‐CD. Peak resolution for six racemic drugs was gradually increased with an increasing degree of substitution of the synthesized CM‐β‐CD. The stoichiometric ratio and binding constants for the inclusion complex formed by CM‐β‐CD and enantiomer were determined, which showed that the stoichiometric ratio for each inclusion complex was 1:1.
Active switched‐capacitor based ultra‐voltage gain quadratic boost DC‐DC converters
Authors: Baba M. F. , Giridhar A. V. , Narasimharaju B. L. 
Published: November 2022

AbstractThis paper presents active switched capacitor integrated ultra‐voltage gain quadratic boost converters (ASC‐QBC). The step‐up conversion ratio provided by quadratic boost converter is not ample to meet the renewable microsource applications. The active switched capacitor integrated quadratic boost converter is a propitious alternate to acquire high voltage conversion ratios. A simple diode‐capacitor voltage lift arrangement is used in one of the introduced converters, thereby further enhancing the voltage gain and also reducing the input current ripple to a greater extent. The voltage stress on semiconductor devices is greatly alleviated with the aid of diode‐capacitor voltage lift arrangement. The input current ripple aspects with green energy sources along with control feasibility of the proposed converters against input voltage and load perturbations are experimentally demonstrated for a power rating of 100 W. The theoretical analysis and performance indices of proposed converters are validated with a fabricated laboratory prototype.
The basics of commonly used molecular techniques for diagnosis, and application of molecular testing in cytology
Authors: Turner Scott A. , Abou Shaar Rand , Yang Zhongbo 
Published: November 2022

AbstractMolecular diagnostics has expanded to become the standard of care for a variety of solid tumor types. With limited diagnostic material, it is often desirable to use cytological preparations to provide rapid and accurate molecular results. This review covers important pre‐analytic considerations and limitations, and a description of common techniques that the modern cytopathologist should understand when ordering and interpreting molecular tests in practice.