bluuebunny/crossref_metadata_2025_split huggingface dataset:
Economic burden of secondary hyperparathyroidism in Germany: a matched comparison
Authors: Reichel Helmut , Seibert Eric , Tillmann Frank-Peter , Barck Isabella , Grava Astride , Schneider Kim Maren , Meise Dominic 
Published: December 2022

Abstract
Purpose
Secondary hyperparathyroidism (SHPT) of renal origin is a progressive complication in chronic kidney disease (CKD) and is associated with serious osseous and non-osseous complications, CKD progression, and economic burden for healthcare systems worldwide. We aimed at assessing characteristics, healthcare resource utilization, and costs of incident SHPT patients in CKD stage 3 (CKD3) and 4 (CKD4), using administrative claims data.

Methods
German claims data were used to identify CKD3 and CKD4 patients, who were stratified by the occurrence of incident SHPT. Patients with SHPT were matched 1:1 to non-SHPT patients with the same CKD stage using propensity scores. Matched groups were compared during a 2-year follow-up period.

Results
Overall, 1156 CKD3 and 517 CKD4 incident SHPT patients and their respective matches were identified. Mean number of all-cause hospitalizations were significantly higher among SHPT patients (2.7 vs. 2.0 in CKD3, 2.8 vs. 1.5 in CKD4) during follow-up. Similarly, the mean number of outpatient encounters was significantly higher among the SHPT cohorts (95.0 vs. 64.3 in CKD3, 101.4 vs. 49.8 in CKD4). SHPT patients progressed to CKD5 more often (6.1% vs. 1.2% from CKD3, 26.7% vs. 2.9% from CKD4, both P < 0.01) resulting in a higher proportion of dialysis (6.1% vs. 1.3% in CKD3, 22.1% vs. 3.7% in CKD4, both P < 0.01). Consequently, average all-cause healthcare costs significantly increased per patient (€19,477 vs. €15,115 in CKD3, €25,921 vs. €12,265 in CKD4).

Conclusions
Patients with CKD3&4 and incident SHPT of renal origin presented with significantly higher healthcare resource utilization and costs, as well as increased disease progression compared to non-SHPT patients.
Community Survey Results Show that Standardisation of Preclinical Imaging Techniques Remains a Challenge
Authors: Tavares Adriana A. S. , Mezzanotte Laura , McDougald Wendy , Bernsen Monique R. , Vanhove Christian , Aswendt Markus , Ielacqua Giovanna D. , Gremse Felix , Moran Carmel M. , Warnock Geoff , Kuntner Claudia , Huisman Marc C. 
Published: December 2022

Abstract
Purpose
To support acquisition of accurate, reproducible and high-quality preclinical imaging data, various standardisation resources have been developed over the years. However, it is unclear the impact of those efforts in current preclinical imaging practices. To better understand the status quo in the field of preclinical imaging standardisation, the STANDARD group of the European Society of Molecular Imaging (ESMI) put together a community survey and a forum for discussion at the European Molecular Imaging Meeting (EMIM) 2022. This paper reports on the results from the STANDARD survey and the forum discussions that took place at EMIM2022.

Procedures
The survey was delivered to the community by the ESMI office and was promoted through the Society channels, email lists and webpages. The survey contained seven sections organised as generic questions and imaging modality-specific questions. The generic questions focused on issues regarding data acquisition, data processing, data storage, publishing and community awareness of international guidelines for animal research. Specific questions on practices in optical imaging, PET, CT, SPECT, MRI and ultrasound were further included.

Results
Data from the STANDARD survey showed that 47% of survey participants do not have or do not know if they have QC/QA guidelines at their institutes. Additionally, a large variability exists in the ways data are acquired, processed and reported regarding general aspects as well as modality-specific aspects. Moreover, there is limited awareness of the existence of international guidelines on preclinical (imaging) research practices.

Conclusions
Standardisation of preclinical imaging techniques remains a challenge and hinders the transformative potential of preclinical imaging to augment biomedical research pipelines by serving as an easy vehicle for translation of research findings to the clinic. Data collected in this project show that there is a need to promote and disseminate already available tools to standardise preclinical imaging practices.
Correlation and interpretation of thermal properties of volcanic rocks from Austria
Authors: Gegenhuber Nina , Dertnig Florian 
Published: December 2022

AbstractThermal properties of rocks are of great importance not only for geothermal projects. The focus of petrophysical data presented here is laid mainly on volcanic rocks. Thermal properties include not only thermal conductivity but also heat production and heat capacity. A full range of dataset and analysis out of it is presented here. The target of this study is to deliver new insights in the thermal properties of volcanic rocks of Austria. The focus is laid on thermal conductivity—understanding of influencing factors and correlations with other properties, like compressional wave velocity, electrical resistivity or radiogenic heat production. Therefore, a set of data from various volcanic rocks of Austria is presented, analysed in detail and new correlations are presented. The correlations can be further applied on logging data to derive thermal properties in the field. These improved correlations and further interpretations can help in planning geothermal projects and can improve the output of simulations because of the better input data.
Tribological Performance of Thin HVAF-Sprayed WC-CoCr Coatings Fabricated Employing Fine Powder Feedstock
Authors: Torkashvand Kaveh , Gupta Mohit , Björklund Stefan , Joshi Shrikant 
Published: December 2022

AbstractIn this study, sliding and abrasion wear performance of WC-CoCr coatings deposited by high velocity air–fuel (HVAF) spraying with various thicknesses (i.e., 240, 150, 100, 50 and 30 µm), fabricated from fine feedstock powder (5–15 µm), were evaluated. The main aim was to investigate how thinner coatings (30 and 50 µm) perform compared to conventional thick coatings (> 100 µm), in an effort to address the supply and cost concerns associated with Co and W. The feedstock powder and deposited coatings were characterized in terms of microstructure. The hardness of the thin and thick coatings was measured using Vickers hardness method from both cross section and top-surface. It was found that, regardless of the thickness, extremely dense coatings with very high hardness (~ 1500 HV) can be deposited employing HVAF and fine feedstock powder. Thin and thick coatings were found to perform similarly under sliding wear with a normal load of 10 N or lower as well as under abrasion wear conditions which highlights the possibility of employing thinner coatings for a majority of the real applications. The results suggest that peening effect does not have a considerable influence on the microstructure or performance of the deposited coatings. However, for sliding wear tests with a 20 N normal load, it was noticed that wear resistance of the coatings slightly declines with decreasing thickness of the coating beyond 150 µm. The main reason was identified to be the involvement of substrate effect when performing tests under severe Hertzian contact pressure.
Alienopterix santonicus sp. n., a metallic cockroach from the Late Cretaceous ajkaite amber (Bakony Mts, western Hungary) documents Alienopteridae within the Mesozoic Laurasia
Authors: Szabó Márton , Szabó Péter , Kóbor Péter , Ősi Attila 
Published: December 2022

Abstract
Cockroaches (Blattaria s. str.) were documented from numerous amber localities around the world, representing both extinct and extant families. Alienopteridae is an extinct cockroach family known only from the Cretaceous of Gondwana (Brazil, Botswana, Myanmar amber) and the Cenozoic of North America. Alienopterix santonicus sp. n. from the Late Cretaceous amber of the Ajka Coal Formation (Bakony Mts, western Hungary) extends the rich geographical distribution of the family into Laurasia during the Mesozoic. As a member of the presumably pollinator cohort Alienopteridae, this species could have played an important role in the Ajka Coal ecosystem during the Santonian. The microrectangular structures of the forewing suggest that the new species likely possessed a metallic colouration already known from the group. Combined with the disruptive body pattern this could have served as an advanced camouflage. The microrectangular structures of the forewing were compared to integument microstructures of extant insects with metallic colouration. Various arthropod taxa are already known from ajkaite, and the new discovery further emphasizes the importance of this amber.
Wessen Perspektiven zählen?
Authors: Hirschbeck Walburga 
Published: December 2022

ZusammenfassungDas Recht auf Beteiligung junger Menschen wird im Kontext der Politikberatung noch nicht ressortübergreifend und strukturell umgesetzt. Bisherige Formate weisen oftmals einen projekthaften Charakter auf und sind intransparent in Hinblick auf die tatsächlichen Mitgestaltungsmöglichkeiten junger Menschen. Eine inklusive und nachhaltige Beteiligung setzt die Bereitschaft voraus, Entscheidungsmacht zu teilen, gezielt Zugänge für benachteiligte junge Menschen zu entwickeln und Beteiligung mit Bildung zu verbinden.
Intra-aortic and Intra-caval Balloon Pump Devices in Experimental Non-traumatic Cardiac Arrest and Cardiopulmonary Resuscitation
Authors: Dogan Emanuel M. , Axelsson Birger , Jauring Oskar , Hörer Tal M. , Nilsson Kristofer F. , Edström Måns 
Published: December 2022

Abstract
Intra-aortic balloon pump (IABP) use during CPR has been scarcely studied. Intra-caval balloon pump (ICBP) may decrease backward venous flow during CPR. Mechanical chest compressions (MCC) were initiated after 10 min of cardiac arrest in anesthetized pigs. After 5 min of MCC, IABP (n = 6) or ICBP (n = 6) was initiated. The MCC device and the IABP/ICBP had slightly different frequencies, inducing a progressive peak pressure phase shift. IABP inflation 0.15 s before MCC significantly increased mean arterial pressure (MAP) and carotid blood flow (CBF) compared to inflation 0.10 s after MCC and to MCC only. Coronary perfusion pressure significantly increased with IABP inflation 0.25 s before MCC compared to inflation at MCC. ICBP inflation before MCC significantly increased MAP and CBF compared to inflation after MCC but not compared to MCC only. This shows the potential of IABP in CPR when optimally synchronized with MCC.
Graphical Abstract
The effect of timing of intra-aortic balloon pump (IABP) inflation during mechanical chest compressions (MCC) on hemodynamics. Data from12 anesthetized pigs.
Short-term outcome after transcatheter aortic valve replacement with a novel balloon-expandable valve
Authors: Halim J. , den Heijer P. , van den Branden B. , Meuwissen M. , Vos J. , Schölzel B. , IJsselmuiden A. 
Published: December 2022

Abstract
Objectives
Transcatheter aortic valve replacement (TAVR) has been expanding rapidly with numerous transcatheter heart valve (THV) systems currently available. The Myval balloon-expandable (BE) valve (Meril Life Sciences Pvt. Ltd., India) is a novel THV system indicated for the treatment of patients with severe aortic stenosis. The primary objective of this study is to assess the safety and performance of the Myval BE valve.

Methods
In this prospective single-centre study, 120 consecutive patients who underwent TAVR with the Myval BE valve were included. Clinical outcomes were evaluated at 30 days and 6 months using Valve Academic Research Consortium‑2 criteria. All-cause mortality, stroke, acute kidney injury, major vascular complications, moderate or severe paravalvular leakage (PVL) and need for a permanent pacemaker implantation (PPI) were investigated.

Results
At 6‑month follow-up, all-cause death and cardiac death were seen in 5.8% and 0.8% of the patients respectively. Periprocedural stroke and need for PPI were both seen in 3.3% of the patients. Access-site-related vascular and bleeding complications were absent. Improved valve haemodynamics and no moderate to severe PVL could be seen at 30 days. An intermediate valve size was selected in 51% of the patients.

Conclusions
The Myval BE valve demonstrates improved valve haemodynamics, absence of moderate to severe PVL and good safety outcomes at 6‑month follow-up with low cardiac death rate and acceptable rates of permanent pacemaker implantation and periprocedural stroke. Future randomised controlled trials will further establish the clinical utility of the Myval BE valve.
Finding early adopters of innovation in social networks
Authors: Sziklai Balázs R. , Lengyel Balázs 
Published: December 2022

AbstractSocial networks play a fundamental role in the diffusion of innovation through peers’ influence on adoption. Thus, network position including a wide range of network centrality measures has been used to describe individuals’ affinity to adopt an innovation and their ability to propagate diffusion. Yet, social networks are assortative in terms of susceptibility and influence and in terms of network centralities as well. This makes the identification of influencers difficult especially since susceptibility and centrality do not always go hand in hand. Here, we propose the Top Candidate algorithm, an expert recommendation method, to rank individuals based on their perceived expertise, which resonates well with the assortative mixing of innovators and early adopters in networks. Leveraging adoption data from two online social networks that are assortative in terms of adoption but represent different levels of assortativity of network centralities, we demonstrate that the Top Candidate ranking is more efficient in capturing innovators and early adopters than other widely used indices. Top Candidate nodes adopt earlier and have higher reach among innovators, early adopters and early majority than nodes highlighted by other methods. These results suggest that the Top Candidate method can identify good seeds for influence maximization campaigns on social networks.
Das Verhältnis von Kunst und Religion in der Philosophie Michel Henrys
Authors: Disse Jörg 
Published: December 2022

ZusammenfassungDer Artikel befasst sich mit der Beziehung zwischen Kunst und Religion in der Philosophie des französischen Phänomenologen Michel Henry. Henry entwickelt eine Philosophie der Kunst, indem er Kandinskys Kunsttheorie auf der Grundlage seiner Phänomenologie des Lebens interpretiert. Kunst ist ein Ausdruck von Leben bzw. Subjektivität. Unter Leben oder Subjektivität versteht Henry die passive Selbstaffektion des Subjekts diesseits intentionaler Selbstreferenz. Selbstaffektion ist nach Henry nur möglich, wenn sich das Individuum, indem es sich auf sich selbst bezieht, gleichzeitig auf das absolute Leben bezieht. Unter Religion aber versteht Henry diese Bindung des Individuums an das absolute Leben. Indem Kunst Ausdruck des Lebens ist, ist sie somit zugleich ein Ausdruck von Religion.
Chinese Firms’ Acquisition of Innovation Capability from Overseas: Approaches by State- versus Private-Owned Firms
Authors: Ghorbani Majid , Xie Zhenzhen , Jin Jun , Wang Fengbin 
Published: December 2022

ABSTRACTThrough two in-depth case studies, we compare the approaches of a state-owned enterprise (SOE), Beijing Automotive Industries Holding Co., and a privately owned enterprise (POE), Geely, to acquire and absorb advanced technological knowledge to enhance their innovation capabilities. Each company acquired advanced knowledge from troubled famous Swedish automakers and upgraded their products technologically. Analyzing data mainly collected from secondary sources identifies major differences in approaches and actions at each acquisition step rooted in the type of ownership. We juxtapose these differences with insights from the literature on knowledge acquisition and research on firm ownership. Our findings show that the POE seeks the strategic goal of synergistic technology integration for better innovation and economic performance. In contrast, the SOE pursues national objectives with less regard for market success. This SOE focuses on an independent approach to knowledge absorption and development during their acquisition, whereas the POE emphasizes collaboration in innovation capacity development. This study provides insights into Chinese firms’ positioning on innovation development on the global stage, comparative capitalism, and the particular case of state capitalism in China.
EXACT SOLUTIONS FOR THE SINGULARLY PERTURBED RICCATI EQUATION AND EXACT WKB ANALYSIS
Authors: NIKOLAEV NIKITA 
Published: December 2022

AbstractThe singularly perturbed Riccati equation is the first-order nonlinear ordinary differential equation
$\hbar \partial _x f = af^2 + bf + c$
in the complex domain where
$\hbar $
is a small complex parameter. We prove an existence and uniqueness theorem for exact solutions with prescribed asymptotics as
$\hbar \to 0$
in a half-plane. These exact solutions are constructed using the Borel–Laplace method; that is, they are Borel summations of the formal divergent
$\hbar $
-power series solutions. As an application, we prove existence and uniqueness of exact WKB solutions for the complex one-dimensional Schrödinger equation with a rational potential.
The Italian validation of the Death and Dying Distress Scale
Authors: Bovero Andrea , Zerbinati Luigi , Grassi Luigi , Mah Kenneth , Rodin Gary , Hales Sarah , Malfitano Carmine , TIberto Elisa , Leombruni Paolo , Miniotti Marco , Caruso Rosangela 
Published: December 2022

AbstractObjectivesDeath anxiety (DA), a condition characterized by fear, angst, or panic related to the awareness of one’s own death, is commonly observed in advanced cancer patients. The aim of this study was to examine the psychometric properties of the Italian version of the Death and Dying Distress Scale (DADDS-IT) in a sample of patients with advanced cancer.MethodsThe sample included 200 Italian advanced cancer patients meeting eligibility criteria to access palliative care. Patients’ levels of DA were assessed by using the DADDS-IT, while the levels of depression, anxiety, demoralization, spiritual well-being, and symptom burden were assessed using the Patient Health Questionnaire-9, the Generalized Anxiety Disorder-7, the Demoralization Scale, the Functional Assessment of Chronic Illness Therapy–Spiritual Well-Being Scale, and the Edmonton Symptom Assessment System, respectively; Karnofsky Performance Status was used to measure functional impairment. Confirmatory factor analyses (CFA) of previous structures and exploratory factor analyses (EFA) were conducted.ResultsCFA revealed that none of the previous structures adequately fitted data from our sample. EFA revealed a 4-factor model comprising Finitude (α = 0.91), Regret (α = 0.86), Dying (α = 0.88), and Relational Burden (α = 0.73), accounting for the 77.1% of the variance. Dying subscore was higher in hospice patients than in those recruited in medical wards.Significance of resultsThe present study provides further evidence that DA is a condition that deserves attention and that DADDS-IT shows good psychometric properties to support its use in research and clinical settings.
Flood Protection Reliability: The Impact of Uncertainty and Nonstationarity
Authors: Stephens T. A. , Bledsoe B. P. 
Published: December 2022

AbstractRecent catastrophic flood events, increasing flood losses, and climate change challenge current reliability estimates defined by the probability that flood levels will not exceed protection measures over a planning horizon. These estimates depict an expected reliability that mask uncertainty in streamflow and the capacity of river channels and floodplains. We described reliability as a random variable whose distribution depends on uncertainty and nonstationarity in annual maximum flood (AMF) distributions and flow capacity uncertainty. Numerical experiments quantified the impacts of nonstationarity and variance in AMFs and flow capacity uncertainty on estimates of flood protection reliability, thereby providing the first examination of their interacting effects. The distribution of reliability along a regulatory floodplain boundary was quantified through a bootstrap scheme that accounts for nonstationarity and uncertainty in AMFs and flow capacity uncertainty. Results indicated that accounting for uncertainty in flow capacity substantially reduces reliability compared to estimates based solely on flood likelihood; the divergence is greater in the presence of nonstationary AMFs. The distribution of reliability along the regulatory floodplain boundary was spatially heterogeneous due to within‐reach variation in flow capacity uncertainty. Quantifying the distribution of reliability for flood protection measures enables transparent communication and selection of a desired confidence level that is commensurate with a contextually appropriate risk tolerance. Similarly, we show that a desired level of confidence in reliability can be specified to estimate a design flood protection level. These results reveal how the combined impacts of uncertainty and nonstationarity can impact reliability estimates and confidence in those estimates.
Thermospheric Nitric Oxide Cooling Responses to the 14 December 2020 Solar Eclipse
Authors: Wang Ningchao , Yu Wandi , Yue Jia , Wang Wenbin , Qian Liying , Mclnerney Joseph M. , Russell James M. , Mlynczak Martin G. 
Published: December 2022

AbstractThe behaviors of the nitric oxide (NO) cooling in the lower thermosphere during the 14 December 2020 solar eclipse are studied using Sounding of the Atmosphere using Broadband Emission Radiometry (SABER) measurements and WACCM‐X simulations. We found that NO cooling rate decreases during the solar eclipse in both SABER measurements and WACCM‐X simulations. The maximum decrease of the NO cooling is 40% in SABER measurements and 25% in WACCM‐X simulations. The NO cooling process is initiated almost entirely through the collisions with atomic oxygen (O) which depends linearly on NO and O densities and non‐linearly on the neutral temperature. During the eclipse, the NO concentration and temperature decreases are larger than that of O concentration. Consequently, the eclipse‐time NO concentration and temperature decreases are the major drivers of the NO cooling rate decrease. The decreases of the temperature and the NO concentration contribute comparably to the eclipse‐time NO cooling rate decrease.
Wind Speed as a Dominant Source of Periodicities in Reported Emission Rates of Volcanic SO2
Authors: Barrington C. , Taisne B. , Costa F. , Arellano S. 
Published: December 2022

AbstractVolcanoes have been found to display periodicities or cyclic trends in a wide range of phenomena. These include the eruptive activity itself, but also in the time series of geophysical and geochemical monitoring data such as volcanic degassing. Here, we test the existence of periodicities of volcanic degassing at 32 volcanoes using the time series of sulfur dioxide (SO2) emission rates from data of the Network for Observation of Volcanic and Atmospheric Change (NOVAC). We use the Lomb‐Scargle periodogram to analyze the SO2 data which allows efficient computation of a Fourier‐like power spectrum from unevenly sampled data. We were able to calculate False‐Alarm Probabilities in 28 of the 32 volcanoes, and we identified significant periodicities in the SO2 emission rates in 17 of the 28 volcanoes. However, we find that most of these periodicities are also present in the plume speeds used to determine SO2 emission rates. Periodicities at about 30–70, ∼120, and ∼180 days were identified at volcanoes located between 16°N and 16°S and are related to intraseasonality and interseasonality in global trade winds and not volcanic in origin. Periodicities between 30 and 70 days in both plume speed and SO2 emission rates are associated to the Madden‐Julian Oscillation that is responsible for intraseasonal variability in the tropical atmosphere. Our study highlights the importance of using local wind data for deriving realistic SO2 emissions and the identification of short‐term periodicity in volcanic behavior.