bluuebunny/crossref_metadata_2025_split huggingface dataset:
How the Big Five personality traits related to aggression from perspectives of the benign and malicious envy
Authors: Jiang Xinsheng , Li Xiaojun , Dong Xia , Wang Lan 
Published: August 2022

Abstract
Background
Prior studies have indicated the link between the Big Five personality traits and aggression. Based on the general aggression model, the purpose of this study is to reveal the formation mechanism of aggression from the people’s internal emotional perspective. Envy is a typical negative emotion that can be divided into benign/malicious envy. Therefore, we aim to explore the intrinsic role of benign/malicious envy within the Big Five personality traits in its connection to aggression.

Methods
We recruited 839 participants [229 men (27.29%) and 610 women (72.71%); mean age ± SD = 19.45 ± 2.39] who we tested with the NEO Personality Inventory, the Benign and Malicious Envy Scale, and the Aggression Questionnaire.

Results
The results of suggested that neuroticism was significantly and positively associated with aggression, while agreeableness was negatively related to aggression. Moreover, mediation analysis revealed that malicious envy works both in the relationship of neuroticism-aggression and agreeableness-aggression.

Conclusions
The current study advanced knowledge of the general aggression model. Most importantly, it reveals that malicious envy, as a type of envy, plays an important mediating role between neuroticism, agreeableness and aggression. Meanwhile, the cross-gender path analysis supports the stability of the mediating role of malicious envy. This finding provides new insights into the intervention of aggression from the perspective of envy.
Determinants of male involvement in family planning services in Abia State, Southeast Nigeria
Authors: Amuzie Chidinma Ihuoma , Nwamoh Uche Ngozi , Ukegbu Andrew , Umeokonkwo Chukwuma David , Azuogu Benedict Ndubueze , Agbo Ugonma Okpechi , Balogun Muhammad Shakir 
Published: August 2022

Abstract
Background
Male involvement in family planning (FP) remains low in male-dominant communities. Family planning contributes to the regulation of fertility and population growth in Nigeria. Increasing male involvement in family planning services is crucial in reducing maternal morbidity and mortality in patriarchal societies such as Nigeria. This study identified the determinants of male involvement in family planning services in Abia State, Nigeria.

Methods
This was a cross-sectional study conducted in twelve communities of Abia State, Nigeria. A total of 588 married men who met the eligibility criteria were recruited using a multistage sampling technique. An interviewer-administered semi-structured questionnaire was used to collect data on the variables. Univariate, bivariate and multivariate analysis was done. The level of significance was set at 5%.

Results
The overall level of active male involvement in family planning services was 55.1% (95% CI:51.0–59.2%). The mean age of the respondents was 42.4 ± 8.0 years. Access to television (aOR = 1.58, 95% CI: 1.05–2.39), spouse employment status (aOR = 2.02, 95% CI: 1.33–2.06), joint decision-making (aOR = 1.66, 95% CI: 1.05–2.62), and accompanying spouse to the FP clinic (aOR = 3.15, 95% CI: 2.16–4.62) were determinants of active male involvement.

Conclusion
At least, one out of every two men was actively involved in family planning services. This was determined by access to television, employment status of spouse, joint decision-making, and accompanying spouse to the FP clinic. There is a need to focus on the identified factors in order to further improve the active involvement of men in FP services.
Cardiovascular complications and predictors of mortality in hospitalized patients with COVID-19: a cross-sectional study from the Indian subcontinent
Authors: Lalani Kanhai , Seshadri Sneha , Samanth Jyothi , Thomas Jaimin Jose , Rao M. Sudhakar , Kotian Nisha , Satheesh Jijin , Nayak Krishnananda 
Published: August 2022

Abstract
Background
COVID-19 has spread rapidly across the world, producing significant morbidity and mortality. We investigated the cardiovascular complications and association of laboratory parameters with severity and mortality predictors in COVID-19 hospitalized patients.

Methods
Between May 2020 and June 2021, 730 COVID-19 patients were included in this retrospective observational study in the Coastal Karnataka region of South India. Acute coronary syndrome (ACS), myocarditis, arrhythmias, and all-cause mortality were reported as cardiovascular consequences. Neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), serum creatinine, D-dimer, troponin T, N-terminal pro-brain natriuretic peptide (NT-ProBNP), serum ferritin, and serum lactate dehydrogenase (LDH) were among the laboratory parameters measured.

Results
Most common electrocardiogram (ECG) changes were prolonged QTc interval (45.6%) followed by ST-T changes (40.7%) and sinus tachycardia (24.2%). 9.2% patients presented with ACS, with 38.8% having ST-elevation myocardial infarction (STEMI) and 61.2% having non-ST elevation myocardial infarction (NSTEMI). In non-survivors, NLR (p < 0.001) and PLR (p = 0.001) were significantly higher. Multivariable regression analysis showed that age (OR:1.019, 95% CI 1.003–1.034; p = 0.017), acute kidney injury (OR:3.562, 95% CI 1.737–7.301; p = 0.001), white blood cell count (WBC) (OR = 1.100, 95% CI 1.035–1.169; p = 0.002), platelet count (OR = 0.994, 95% CI 0.990–0.997; p = 0.001), PLR (OR = 1.002, 95% CI 1.000–1.004; p = 0.023) and severe COVID-19 (OR = 9.012, 95% CI 3.844–21.129; p = 0.001) were independent predictors of mortality in COVID-19 patients.

Conclusions
Age, WBC count, neutrophil%, NLR, PLR, creatinine, D-dimer, ferritin, LDH, tachycardia, and lymphocytes% strongly correlated with the severity of the disease. Age, acute kidney injury, elevated WBC count, a greater PLR, low platelet count, and COVID-19 severity were independent predictors of mortality.
Survey of control techniques to alleviate repercussions of shock-wave and boundary-layer interactions
Authors: Jana Tamal , Kaushik Mrinal 
Published: August 2022

AbstractThe primary focus of the present survey is to categorize the results of various investigations on the Shock/Boundary-Layer Interactions (SBLIs), their repercussions, and the effective ways to control them. The interactions of shock waves with the boundary layer are an important area of research due to their ubiquity in several applications ranging from transonic to hypersonic flows. Therefore, there is a need for a detailed inspection to understand the phenomena to predict its characteristics with certain accuracy. Considering this in mind, this article presents some key features of the physical nature of SBLIs, their consequences, and the control techniques in a sequential manner; in particular, the passive control techniques for the supersonic and hypersonic intakes are reviewed in detail.
Neoadjuvant Chemotherapy, Excision, and Observation for Early Rectal Cancer: The Phase II NEO Trial (CCTG CO.28) Primary End Point Results
Authors: Kennecke Hagen F. , O'Callaghan Chris J. , Loree Jonathan M. , Moloo Hussein , Auer Rebecca , Jonker Derek J. , Raval Manoj , Musselman Reilly , Ma Grace , Caycedo-Marulanda Antonio , Simianu Vlad V. , Patel Sunil , Pitre Lacey D. , Helewa Ramzi , Gordon Vallerie L. , Neumann Katerina , Nimeiri Halla , Sherry Max , Tu Dongsheng , Brown Carl J. 
Published: August 2022

PURPOSE Organ-sparing therapy for early-stage I/IIA rectal cancer is intended to avoid functional disturbances or a permanent ostomy associated with total mesorectal excision (TME). The objective of this phase II trial was to determine the outcomes and organ-sparing rate of patients with early-stage rectal cancer treated with neoadjuvant chemotherapy followed by transanal excision surgery (TES). METHODS This phase II trial included patients with clinical T1-T3abN0 low- or mid-rectal adenocarcinoma eligible for endoscopic resection who were treated with 3 months of chemotherapy (modified folinic acid–fluorouracil-oxaliplatin 6 or capecitabine-oxaliplatin). Those with evidence of response proceeded to transanal endoscopic surgery 2-6 weeks later. The primary end point was protocol-specified organ preservation rate, defined as the proportion of patients with tumor downstaging to ypT0/T1N0/X and who avoided radical surgery. RESULTS Of 58 patients enrolled, all commenced chemotherapy and 56 proceeded to surgery. A total of 33/58 patients had tumor downstaging to ypT0/1N0/X on the surgery specimen, resulting in an intention-to-treat protocol-specified organ preservation rate of 57% (90% CI, 45 to 68). Of 23 remaining patients recommended for TME surgery on the basis of protocol requirements, 13 declined and elected to proceed directly to observation resulting in 79% (90% CI, 69 to 88) achieving organ preservation. The remaining 10/23 patients proceeded to recommended TME of whom seven had no histopathologic residual disease. The 1-year and 2-year locoregional relapse-free survival was, respectively, 98% (95% CI, 86 to 100) and 90% (95% CI, 58 to 98), and there were no distant recurrences or deaths. Minimal change in quality of life and rectal function scores was observed. CONCLUSION Three months of induction chemotherapy may successfully downstage a significant proportion of patients with early-stage rectal cancer, allowing well-tolerated organ-preserving surgery.
Physical organogenesis of the gut
Authors: Chevalier Nicolas R. 
Published: August 2022

ABSTRACT
The gut has been a central subject of organogenesis since Caspar Friedrich Wolff’s seminal 1769 work ‘De Formatione Intestinorum’. Today, we are moving from a purely genetic understanding of cell specification to a model in which genetics codes for layers of physical–mechanical and electrical properties that drive organogenesis such that organ function and morphogenesis are deeply intertwined. This Review provides an up-to-date survey of the extrinsic and intrinsic mechanical forces acting on the embryonic vertebrate gut during development and of their role in all aspects of intestinal morphogenesis: enteric nervous system formation, epithelium structuring, muscle orientation and differentiation, anisotropic growth and the development of myogenic and neurogenic motility. I outline numerous implications of this biomechanical perspective in the etiology and treatment of pathologies, such as short bowel syndrome, dysmotility, interstitial cells of Cajal-related disorders and Hirschsprung disease.
Efficacy analysis of C5V chemotherapy combined with transcatheter subcutaneous radiofrequency ablation in the treatment of children with advanced (Stage III/IV) hepatoblastoma
Authors: Qi Yan-wei , Liu Wei-dong , Gao Lei , Gong Ying-xin 
Published: August 2022

Objectives: To evaluate the clinical efficacy of C5V chemotherapy combined with transcatheter subcutaneous radiofrequency ablation in the treatment of children with advanced (stage III/IV) hepatoblastoma.
Methods: Eighty children with advanced (Stage III/IV) hepatoblastoma were admitted in Hebei Children’s Hospital from May 2019 to September 2021 randomly divided into two groups: control group and experimental group, with 40 cases in each group. Children in the control group received C5V chemotherapy, while those in the experimental group received C5V chemotherapy combined with transcatheter subcutaneous radiofrequency ablation. After treatment, the treatment effect, adverse drug reactions, AFP, ALT, AST, HBG and other indicators of the two groups were compared and analyzed. And the difference in survival rate and recurrence rate between the two groups was compared and analyzed.
Results: The total efficacy of the experimental group was 67.5%, which was significantly better than 45% of the control group (p=0.04). The incidence of adverse drug reactions in the experimental group was 50%, while that in the control group was 35% (p=0.15). After treatment, AFP, ALT and AST in the experimental group were significantly lower than those in the control group, while the HBG was slightly higher than that of the control group (p=0.03). Moreover, the overall survival rate of the experimental group was significantly higher than that of the control group, and the recurrence rate was significantly lower than that of the control group.
Conclusion: C5V chemotherapy combined with transcathetal subcutaneous radio fascial ablation is a safe and effective regimen for children with advanced (stage III/IV) hepatoblastoma, boasting definite efficacy and no increase in adverse reactions.
doi: https://doi.org/10.12669/pjms.38.7.5899
How to cite this:Qi Y, Liu W, Gao L, Gong Y. Efficacy analysis of C5V chemotherapy combined with transcatheter subcutaneous radiofrequency ablation in the treatment of children with advanced (Stage III/IV) hepatoblastoma. Pak J Med Sci. 2022;38(7):---------. doi: https://doi.org/10.12669/pjms.38.7.5899
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Older adults and family caregivers’ experience of digital health technology in frailty care: A systematic review and meta-ethnography protocol
Authors: Darley Andrew , Dix Rachael , Rocher Elena , Stokes Diarmuid , Carroll Áine 
Published: August 2022

Background: Digital health technology has been identified as a valuable tool to support older adults with frailty needs in their home setting. Despite the numerous technologies and evaluations of these innovations, a synthesis of the older person and family caregivers’ experience using technology for support self-management has not been conducted to date. Methods and analysis: A systematic review and meta-ethnography will be conducted in accordance with the PRISMA and eMERGe reporting guidelines. Four peer-reviewed empirical evidence databases will be searched (Medline (Ovid), CINAHL, EMBASE, PsycINFO) using a defined search strategy. Studies containing qualitative data on the experiences of older people or family caregivers of using digital health technology to support frailty care will be included. Covidence software will be used to screen studies and extract data. The Critical Appraisal Skills Programme (CASP) checklist for qualitative research will be used by two independent reviewers to appraise all included papers. A meta-ethnography will be undertaken in accordance with the seven-phase method described by Noblit and Hare: (1) Getting started, (2) Deciding what is relevant to the initial interest, (3) Reading the studies, (4) Determining how the studies are related, (5) Translating the studies into one another, (6) Synthesizing translations and (7) Expressing the synthesis. Discussion: To the best of our knowledge, this will be the first systematic review to integrate and synthesize the findings of qualitative studies of older citizens’ experience of digital health technology. The findings of this meta-ethnography will endeavour to inform future research, policy and clinical practice. In particular, the results will help to inform the design of future digital health technology to meet the needs of older adults. PROSPERO registration number: CRD42022314608.
Finding Feasible Systems for Subjective Constraints Using Recycled Observations
Authors: Zhou Yuwei , Andradóttir Sigrún , Kim Seong-Hee , Park Chuljin 
Published: August 2022

We consider the problem of finding a set of feasible or near-feasible systems among a finite number of simulated systems in the presence of stochastic constraints. When the constraints are subjective, a decision maker may want to test multiple threshold values for the constraints. Or the decision maker may simply want to determine how a set of feasible systems changes as constraints become more strict with the objective of pruning systems or finding the system with the best performance. When only the constraint thresholds change for the same set of underlying systems, it is natural to reuse observations collected from the feasibility check with a different threshold value. We present an indifference-zone procedure that recycles observations and provide an overall probability of correct decision for all threshold values. Our numerical experiments show that the proposed procedure performs well in reducing the required number of observations while providing a statistical guarantee on the probability of correct decision.Summary of Contribution: We consider the problem of determining the feasibility of a finite number of systems in the presence of subjective constraints on performance measures that can be estimated only by stochastic simulation. Specifically, our work focuses on the situation where the decision maker is willing to relax some constraint thresholds if necessary to achieve feasibility. Also, we discuss how our proposed procedures can help select the best system in the presence of multiple objectives. This is the first work that considers subjective constraints in the field of ranking and selection in simulation and it provides a practically useful decision-making tool with more flexibility on feasibility determination.History: Accepted by Bruno Tuffin, Area Editor for Simulation.Supplemental Material: The online supplement is available at https://doi.org/10.1287/ijoc.2022.1227 .
Bystanders Join in Cyberbullying on Social Networking Sites: The Deindividuation and Moral Disengagement Perspectives
Authors: Chan Tommy K. H. , Cheung Christy M. K. , Benbasat Izak , Xiao Bo , Lee Zach W. Y. 
Published: August 2022

Bystanders Join in Cyberbullying on Social Networking Sites: The Deindividuation and Moral Disengagement Perspectives Cyberbullying on social networking sites escalates when bystanders join in the bullying. Bystanders’ joining-in behaviors reinforce the abuse, expose victims to a larger audience, and encourage further abuse by signaling their approval of the aggressive behavior. This study developed an integrative model that explains bystanders’ joining-in cyberbullying behaviors on SNSs to offer actionable insights into reducing such harmful behaviors. We tested the model using 1,179 responses using a scenario survey study. Our findings suggest that IT artifacts (including digital profile, search and privacy, relational ties, and network transparency) activated two key mechanisms that lead to cyberbullying joining-in behaviors: (i) the deindividuation experiences that attenuate self-identity and put salience on group/social identity, and (ii) the moral disengagement practices that permit the exercise of cognitive maneuvers to justify group-interested choices that do not align with social standard. The findings explain why people who do not know each other gang up to bully a target on social media. Platform owners who wish to discourage bystanders from joining in undesirable activities may consider regulating how users could share and access digital resources in a social network and should acknowledge the influence of social identity in igniting, driving, and prolonging harmful online group behaviors.
Living well with heart failure: evaluation of an education and support programme for patients and caregivers
Authors: Butcher Dan , Walthall Helen , Wee Bee 
Published: August 2022

Background/Aims Living with advanced heart failure places a considerable burden on patients and their caregivers. Improving the education and support given to patients and caregivers, with the input of palliative care services, could support them to live well with heart failure. This study evaluated an 8-week programme of education and support delivered in a day hospice for patients diagnosed with heart failure and their informal caregivers. Methods An 8-week programme was delivered five times between January 2018 and March 2019, with a total of 39 participants (24 patients and 15 caregivers). Two focus groups were conducted at the end of each programme (one with patients and one with caregivers). Groups were recorded and transcribed verbatim, and inductive thematic analysis was performed. Results Most patient participants were male (92%) and aged >70 years, while most caregiver participants were female (93%) and aged >50 years. The main themes from the patient participants' focus groups regarding the programme were the importance of knowledge; support and communication; having a gateway to resources; and the concept of living with heart failure. The main themes from the caregiver participant focus groups were becoming stronger; altered outcomes for the future; and connection through knowledge. All participants gave positive feedback about the programme, with increased knowledge about heart failure and access to peer support being highlighted as particularly valuable. Conclusions This hospice-based model of support and education, involving patients and their caregivers, has considerable potential as a means of helping these individuals to live well with heart failure. Greater integration between cardiac services and palliative care is needed to support this growing patient group.
A student coaching in practice (SCiP) approach: the impact on adult field pre-registration nursing students
Authors: Norman Kay 
Published: August 2022

Background: A ‘student coaching in practice’ (SCiP) approach, based on the OSCAR and GROW model of coaching, was implemented across three UK NHS trusts in the West Midlands, involving seven placement areas that consisted of both acute and community hospital settings. Aim: To explore the impact of a SCiP approach on preparing students for their next stage of learning and perceived confidence. Method: Seventy nursing students across Years 1, 2 and 3 of their BSc (Hons) programme took part in the study through completing an evaluative survey consisting of both quantitative and qualitative responses. Ethical approval was obtained by the host university. Findings: Participants across each year group found SCiP beneficial in developing learning and skills in practice, helped them prepare for the next stage of learning or registration, and increased perceived confidence. Students in year 1 and year 3 of their nursing programme gave the most positive responses. Implementing SCiP resulted in the expansion of placement capacity.
Working in partnership to implement change in wound dressings use
Authors: Mangan Maggie , Shoreman Sara 
Published: August 2022

Background: Wound care provision relies on safety, effectiveness, patient acceptance and accessibility of selected wound management products, supported by a sound education programme. Challenges with changing patient needs and service provision before and during the COVID-19 pandemic have resulted in new training and service delivery programmes to manage increased prevalence of wounds with dwindling resources. Method: South Warwickshire University NHS Foundation Trust incorporated a wound care audit identifying local challenges, available resources and areas for improvement, which led to changes in practice around training and the supply of dressings. This article sets out the rationale for change and steps taken to implement new practice, keeping the patient at the heart of care while following clinical governance. Results: The new practice resulted in a rigorous training programme to cover total wound management from assessment to standardised treatment that could encourage self-care where possible and improve patient outcomes. Wise use of all resources to manage stock levels released more qualified staff to focus on complex cases. Non-prescription ordering of dressings reduced stock wastage and the Trust recorded cost savings of more than 25% on the previous year. Conclusion: Sound wound care practice aligned to the National Wound Care Strategy, training in partnership with industry and the use of an efficient dressings delivery system achieved positive patient outcomes and significant financial savings for the Trust.