bluuebunny/crossref_metadata_2025_split huggingface dataset:
Akzeptanz und Nutzungsbedingungen digitaler Interventionen zur Distressprävention bei Studierenden
Authors: Krümmel Anne , Laiker Isabella , Wrona Kamil J. , Aschentrup Leona , Dockweiler Christoph 
Published: October 2022

Zusammenfassung
Hintergrund
Das ausbildungsbezogene Stressempfinden auf Ebene von Distress von Studierenden stellt ein hohes Risiko für die Entstehung von psychischen Erkrankungen dar. Die konsequente Nutzung digitaler Anti-Stress-Apps kann dazu beitragen, Versorgungsdefizite in der Vermeidung von stressinduzierten Erkrankungen wirksam auszugleichen, wenn existierende Hilfsangebote nicht genutzt werden, oder helfen, Barrieren zur Nutzung bestehender Interventionsmaßnahmen mindern. In diesem Kontext untersucht der vorliegende Beitrag die Einstellungsakzeptanz und die verbundenen Nutzungsbedingungen Studierender der Universität Bielefeld gegenüber digitalen Anti-Stress-Apps. Basierend auf der Akzeptanz und den Nutzungsbedingungen sollen Anforderungen für die bessere Implementierung digitaler Interventionen geleitet werden.

Methodik
Die Erhebung wurde mittels qualitativer leitfadengestützter Interviews und quantitativer Umfragen an denselben 15 Studierenden (n = 14 Frauen und einem Mann im Alter von 22 bis 31 Jahren) der Universität Bielefeld durchgeführt. Für die Auswertung der Interviews wurde die strukturierte Inhaltsanalyse nach Mayring herangezogen, bei der mit Hilfe von deduktiven und induktiven Kategorien die Transkripte analysiert wurden. Zur Strukturierung und Analyse der Ergebnisse wurde die „unified theory of acceptance and use of technology 2“ (UTAUT 2) eingesetzt.

Ergebnisse
Anhand der UTAUT 2 konnten bedürfnisorientierte Bedingungen zur Nutzung und Einstellung hinsichtlich der Akzeptanz identifiziert werden. Die Einstellungsakzeptanz von Studierenden zu Anti-Stress-Apps ist weitestgehend positiv, geht jedoch nicht einher mit dem Nutzungsverhalten. Die Ergebnisse weisen eine starke Abhängigkeit von individuellen Bedürfnissen auf, was zudem von verschiedenen Alltagssituationen ausgeht, in denen Stress individuell empfunden wird.

Schlussfolgerungen
Bedingungen an die vorhandenen Elemente und Interventionen in einer App zur Stressreduktion müssen in der Softwareentwicklung berücksichtigt werden, damit die Anwendung subjektiv als wirksam wahrgenommen wird. Der Ausbau und die Einführung bedürfnisorientierter Angebote in die Lebenswelt der Nutzer*innen und Nutzergruppen sowie begleitende Maßnahmen zur zielgruppenspezifischen Sensibilisierung, können die Akzeptanz weiter steigern, das Nutzungsverhalten positiv beeinflussen und gegen Stressbelastungen wirken.
Towards coherence on sustainability in education: a systematic review of Whole Institution Approaches
Authors: Holst Jorrit 
Published: October 2022

AbstractOrienting societies towards sustainability requires comprehensive learning of how to think, act and live within a safe and just space for humanity. Approaching sustainability as a core paradigm of quality education in the twenty-first century, Education for Sustainable Development necessitates an integrated view on learning. For educational organizations, Whole Institution Approaches (WIAs) to sustainability emphasize that all learning is embedded within its socio-physical contexts. Although the core objective—to “walk the talk” on sustainability—is theoretically well established, questions remain regarding its specific conceptualizations. Based on a systematic qualitative analysis of 104 international documents from scientific and grey literature, this article offers a conceptual synthesis of the core elements of WIAs to sustainability in education. Based on the literature analysis, WIAs are described as continuous and participative organizational learning processes aimed at institutional coherence on sustainability, consistently linking the formal and informal (hidden) curricula. While specific pathways are necessary for diverse organizations, the article synthesizes a joint framework. Key characteristics of WIAs are clustered within five core principles (coherence, continuous learning, participation, responsibility, long-term commitment), seven highly integrated areas of action (governance, curriculum, campus, community, research, communication, capacity building), the underlying organizational culture, and critical conditions for successful implementation. As becomes clear from the synthesis, following a WIA means to collaboratively switch the default mode of all rules-in-use to sustainability. The concept of WIAs may thus both be approached as an instrument for consistent organizational development in light of (un-)sustainability and as a keystone of integrated high-quality sustainability learning.
Bankart-Plus zur Behandlung von Patienten mit anteriorer Schulterinstabilität und kleinen bis moderaten Glenoiddefekten
Authors: Minkus Marvin , Akgün Doruk , Thiele Kathi , Karpinski Katrin , Moroder Philipp 
Published: October 2022

ZusammenfassungHintergrundEine große Anzahl an Patienten mit Schulterinstabilität weisen kleine bis moderate Glenoiddefekte auf, die unterhalb der Grenze zur knöchernen Augmentation liegen, jedoch groß genug sind, die klinischen Ergebnisse der konventionellen Weichteilstabilisierung zu kompromittieren.Material und MethodenIn einer prospektiven Studie werden 30 Patienten, die eine anteriore Schulterinstabilität mit kleinen Glenoiddefekten (maximal 15 % der Gelenkfläche) aufweisen, eingeschlossen und in der sog. Bankart-Plus-Technik operiert, welche eine Refixation des Kapsel-Labrum-Komplexes mithilfe von knotenlosen Ankern sowie die Augmentation mit einem Interponat aus demineralisierter spongiöser Knochenmatrix (DCBM) zwischen Labrum und Glenoid umfasst. Die Patienten werden prä- und postoperativ (6, 12 und 24 Monate) mit Erhebung des Western Ontario Shoulder Instability Index (WOSI), Rowe Score (RS) und Subjective Shoulder Value (SSV) klinisch untersucht. Die präoperative Bildgebung umfasst eine CT mit dreidimensionaler (3D-)Rekonstruktion zur Bestimmung des Glenoiddefekts (PICO-Methode). Nach 12 Monaten erfolgt eine MRT-Untersuchung der operierten Schulter zur Beurteilung der Einheilung des Labrums und Grafts.ErgebnisseEingeschlossen wurden 30 Patienten (Durchschnittsalter 28 [Range 18–40] Jahre,n = 4 weiblich,n = 26 männlich) und in der vorbeschriebenen Technik zwischen 09/2018 und 10/2020 operiert. In 13 Fällen (43 %) wurde zusätzlich eine Remplissage durchgeführt. Präoperativ wurden die folgenden klinischen Scores erhoben (Mean): WOSI 45 ± 17 %, RS 56 ± 10 Punkte und SSV 57 ± 19 %. Die präoperativen CT-Untersuchungen ergaben einen Glenoiddefekt von durchschnittlich 7 ± 3 %. Bisher liegen bei 25 Patienten die klinischen und radiologischen Ergebnisse nach 12 Monaten vor und es zeigt sich eine signifikante Verbesserung verglichen mit den präoperativen Daten (p < 0,05): WOSI 81 ± 15 %, RS 91 ± 8 Punkte und SSV 87 ± 10 %. Bisher zeigten sich keine Rezidivluxationen und keine Komplikationen. Die MRT-Untersuchungen zeigten eine gute Integration des Labrums und Grafts am vorderen Glenoidrand mit Wiederherstellung der Konkavität.SchlussfolgerungDie Bankart-Plus-Operation zeigt vielversprechende klinische und radiologische Ergebnisse im kurzfristigen Follow-up und ist eine praktikable Behandlungsoption für Patienten mit Schulterinstabilität, die einen kleinen bis moderaten Glenoiddefekt aufweisen.
Winning your customers’ minds and hearts: Disentangling the effects of lock-in and affective customer experience on retention
Authors: Gao Lily , de Haan Evert , Melero-Polo Iguácel , Sese F. Javier 
Published: October 2022

AbstractBuilding barriers to lock in customers and improving the affective customer experience are two key strategies employed by firms to enhance customer retention. Although pursuing the same goal, these strategies work differently: the former relies more on a calculative, cost–benefit approach to the exchange, while the latter promotes affective aspects of the relationship. Integrating experiential learning theory with social exchange theory, we provide a conceptual framework to understand the impact of lock-in and affective customer experience on customer retention, and the moderating role of relationship depth. Using a comprehensive data set for a sample of 13,761 customers covering all firms in one telecom market for two different services, we empirically test the framework via multinomial logit modeling. The results offer novel insights into the interplay between the two strategies. For poor affective customer experience (i.e., a score below five on a 0–10 scale), lock-in helps firms reduce customer churn (between 49.03% and 47.86%). However, the impact of lock-in decreases when affective customer experience improves and turns to be insignificant once the experience reaches the “acceptable level” (i.e., a score above seven on a 0–10 scale). Importantly, the separate and joint effects of the two strategies are stronger when there is a low relationship depth, and weaker when heavy relationships are established. The findings offer useful practical advice to manage these strategies in an efficient and optimal way.
Cognitive and Neuropsychiatric Impairment in Dystonia
Authors: Bailey Grace A. , Martin Eva , Peall Kathryn J. 
Published: October 2022

Abstract
Purpose of Review
To review recent literature evaluating psychiatric and cognitive symptoms in dystonia, the two non-motor symptom groups most frequently evaluated in dystonia research and recognised in clinical practice.

Recent Findings
Recent work has embedded clinical recognition of psychiatric symptoms in dystonia, with depressive and anxiety-related symptoms routinely observed to be the most common. Less explored symptoms, such as self-harm, suicidal ideation, and substance abuse, represent newer areas of investigation, with initial work suggesting higher rates than the background population. Investigation of cognitive function has provided less consistent results, both within individual dystonia subtypes and across the spectrum of dystonias, partly reflecting the heterogeneity in approaches to assessment. However, recent work indicates impairments of higher cognitive function, e.g. social cognition, and disrupted visual and auditory sensory processing.

Summary
Dystonia demonstrates psychiatric and cognitive symptom heterogeneity, with further work needed to recognise endophenotypes and improve diagnostic accuracy, symptom recognition, and management.
The androgen receptor-targeted proteolysis targeting chimera and other alternative therapeutic choices in overcoming the resistance to androgen deprivation treatment in prostate cancer
Authors: Li Liuxun , Xu Jiangli 
Published: October 2022

AbstractAndrogen receptor (AR) plays a vital role in prostate cancer (PCa), including castration-resistant PCa, by retaining AR signalling. Androgen deprivation treatment (ADT) has been the standard treatment in the past decades. A great number of AR antagonists initially had been found effective in tumour remission; however, most PCa relapsed that caused by pre-translational resistance such as AR mutations to turn antagonist into agonist, and AR variants to bypass the androgen binding. Recently, several alternative therapeutic choices have been proposed. Among them, proteolysis targeting chimera (PROTAC) acts different from traditional drugs that usually function as inhibitors or antagonists, and it degrades oncogenic protein and does not disrupt the transcription of an oncogene. This review first discussed some essential mechanisms of ADT resistance, and then introduced the application of AR-targeted PROTAC in PCa cells, as well as other AR-targeted therapeutic choices.
In the Name of the Neighbor: The Associations between Racial Attitudes, Intergroup Contacts, Ethnic Diversity, and the Perception of Names in the Dutch Speaking Part of Belgium
Authors: Martiniello Billie , Verhaeghe Pieter-Paul 
Published: October 2022

AbstractCorrespondence testing is an increasingly used method to measure ethnic discrimination. Hereby researchers make use of names to signal ethnic origin. Nevertheless, it is rather rare that the used names are thoroughly pretested. Names are implicitly or explicitly assumed to contain clear signals of ethnic origin. Besides, individual differences in ethnic perceptions of names are ignored. Therefore, this study aims to analyze how the ethnic perception of Polish, Moroccan, Turkish, and Congolese names differ according to one’s negative racial attitudes and intergroup contacts as well as the ethnic diversity of the municipality where one resides. We conducted a survey among 990 ethnic majority members in the Dutch-speaking part of Belgium. People with more negative blatant attitudes find it harder to perceive the ethnic origin of names as compared to people with less negative blatant attitudes. The opposite holds for people with negative subtle attitudes. More ethnic diversity in the municipality where one resides makes it easier to recognize Moroccan, Turkish, and Congolese names, but not Polish names. This implies that the level of ethnic discrimination is probably underestimated among people with blatant racial attitudes, as well as among respondents that live in less diverse areas.
Firstborn children’s sex specific emotions and behaviors during mothers’ second pregnancy after implementation of the universal two-child policy in China
Authors: Yang Bo , Sheng LuLu , Huang Xin , Li YueYue , Fang Bo , Wen Yi , Robbins Sarah , Liu Qin 
Published: October 2022

AbstractThe present cross-sectional study aimed to identify sex-specific characteristics and other factors for firstborn children’s emotions and behaviors during their mothers’ second pregnancy after the implementation of the two-child policy in China. Firstborn children aged 1.5–5 years old and their pregnant mothers were enrolled from two hospitals from March to September 2019 in our city. Mothers completed a self-designed questionnaire and Child Behavior Checklist during their routine prenatal examinations. Linear regression was used to explore potential factors influencing firstborn children’s behaviors and emotions towards their mother’s second pregnancy. A total of 880 firstborn children were included. There was no significant difference in internalizing/externalizing problem scores and prevalence between male and female firstborn children during their mothers’ second pregnancy. Children’s easy temperament, good parental relationship, and father’s authoritative and indulgent parenting styles were potential positive factors for both male and female firstborn children. Harmonious family environment, children’s age, father's accompaniment, and being informed by parents of the arrival of a sibling were only related to firstborn girls experiencing fewer emotional and behavioral problems. Mother’s education and seeking for firstborn children’s opinion about the new sibling were only related to firstborn boys experiencing fewer emotional and behavioral problems. There was no sex differences in internalizing/externalizing problems in firstborn children during their mother’s second pregnancy. Children’s temperament, family environment and fathers’ parenting styles were consistent influencing factors for both firstborn girls’ and boys’ emotions and behaviors.
Challenges in integrating molecular profiles into clinical cancer care
Authors: Jahn Stephan W. , Jost Philipp J. 
Published: October 2022

SummaryProfiling of malignancies with next-generation sequencing (NGS) is now routine in clinical practice. While many cases of approved targeted therapies are straightforward based on well-characterized alterations, applying large NGS multigene panels to therapeutic use is frequently challenging. In this article, variant interpretation, therapy matching, and final treatment selection challenges are discussed.
Radiofrequency Identification—RFID using LOCalizer-Tag in Non-palpable Breast Lump
Authors: Parisi Simona , Gambardella Claudio , Ruggiero Roberto , Tolone Salvatore , Lucido Francesco Saverio , Docimo Ludovico 
Published: October 2022

Abstract
For many years, wire-guided localization represented the gold standard method for the detection of non-palpable breast lesions, despite the acknowledged limitations. LOCalizer™ is the most recent and promising radiofrequency identification system, characterized by the capability of measuring the distance from the tagged lesion in millimeters and the association of each marker with a unique code. A 45-year-old woman with two lesions suspected of cancer in the same breast was referred to our department. She underwent double localization with LOCalizer™ (Hologic, Santa Carla, CA, USA) of the lumps into opposite quadrants. We performed a mini-invasive and oncologically safe surgical excision through a tunneling approach after a peri-areolar incision. The surgical technique realized with Localizer™ could be an effective method for locating multiple non-palpable breast lesions and is able to offer excellent oncological and cosmetic results, as also confirmed by several reports in the literature.
Experimental Study on the Influence of Cross-Section Type of Marine Cable Conductors on the Bending Performance
Authors: Yan Jun , Hu Hai-tao , Lu Hai-long , Yin Yuan-chao , Bu Yu-feng , Lu Qing-zhen 
Published: October 2022

AbstractThrough the development of marine energy, marine cables are the key equipment for transmission of electrical energy between surface platforms and underwater facilities. Fatigue failure is a critical failure mode of marine cables. The bending performance of the cable conductor has a major influence on both bending and fatigue performances of the overall cable structure. To study the influence of different types of the conductor cross-section on the bending performances of marine cable conductors, three types of copper conductors with the same cross-sectional area, i.e., noncompressed round, compressed round, and shaped wire conductors, were selected. The experimental results demonstrated that the cross-section type significantly affects the bending performances of copper conductors. In particular, the bending stiffness of the shaped wire conductor is the highest among the three conductor types. Four key evaluation parameters, i.e., the bending stiffness, maximum bending moment, envelope area, and engineering critical slip point, were selected to compare and analyze the bending hysteresis curves of the three copper conductors. The differences in the key evaluation parameters were analyzed based on the structural dimensional parameters, processing methods, and classical bending stiffness theoretical models of the three copper conductor types. The results provide an important theoretical guidance for the structural design and engineering applications of marine cable conductors.
The Association Between the Bared-Teeth Display and Social Dominance in Captive Chimpanzees (Pan troglodytes)
Authors: Kim Yena , Vlaeyen Jolinde M. R. , Heesen Raphaela , Clay Zanna , Kret Mariska E. 
Published: October 2022

AbstractHumans use smiles — widely observed emotional expressions — in a variety of social situations, of which the meaning varies depending on social relationship and the context in which it is displayed. The homologue of the human smile in non-human primates — both due to morphological and functional similarities — is the bared-teeth display (BT). According to the power asymmetry hypothesis (PAH), species with strict linear dominance hierarchies are predicted to produce distinct communicative signals to avoid escalations of social conflicts. Hence, while the BT in a despotic species is predicted to be expressed from low- to high-ranking individuals, signaling submission, the BT in a tolerant species is predicted to be expressed in multiple contexts, regardless of rank. We tested this hypothesis in a group of 8 captive chimpanzees (Pan troglodytes), a species commonly characterized as rather despotic. An investigation of 11,774 dyadic social interactions revealed this chimpanzee group to have a linear dominance hierarchy, with moderate steepness. A Bayesian GLMM — used to test the effects of social contexts and rank relationships of dyads on the use of the BT display — indicated multi-contextual use of the BT which is contingent on the rank relationship. We also found that slight morphological and/or acoustic variants (i.e., silent bared-teeth and vocalized bared-teeth) of the BT display may have different communicative meanings. Our findings are in line with the prediction derived from the PAH for a moderately despotic species, and the view that the human smile originated from the primate BT display.
TSNAdb v2.0: The Updated Version of Tumor-Specific Neoantigen Database
Authors: Wu Jingcheng , Chen Wenfan , Zhou Yuxuan , Chi Ying , Hua Xiansheng , Wu Jian , Gu Xun , Chen Shuqing , Zhou Zhan 
Published: October 2022

Abstract
In recent years, neoantigens have been recognized as ideal targets for tumor immunotherapy. With the development of neoantigen-based tumor immunotherapy, comprehensive neoantigen databases are urgently needed to meet the growing demand for clinical studies. We have built the tumor-specific neoantigen database (TSNAdb) previously, which has attracted much attention. In this study, we provide TSNAdb v2.0, an updated version of the TSNAdb. TSNAdb v2.0 offers several new features, including (1) adopting more stringent criteria for neoantigen identification, (2) providing predicted neoantigens derived from three types of somatic mutations, and (3) collecting experimentally validated neoantigens and dividing them according to the experimental level. TSNAdb v2.0 is freely available at https://pgx.zju.edu.cn/tsnadb/.
West Africa Seen from Moroccan Manuscript Archives
Authors: Nobili Mauro 
Published: October 2022

AbstractThe Area Studies paradigm that emerged in the United States in the late 1950s surely fostered research on parts of the world that had traditionally been neglected in academia, such as the African continent. However, this paradigm also had its shortcomings. Among these shortcomings, there is the tendency to disconnect North Africa from the rest of the continent. Recent works on trans-Saharan connections are a testimony of the potential of studying African history across the Sahara and from a continental perspective. This article demonstrates this potential by presenting a large corpus of Arabic manuscripts concerning West African history held in two of the most important libraries of Morocco: The Bibliothèque Royale Hasaniyya / al-Khizāna al-Ḥasaniyya and the Bibliothèque Nationale du Royaume du Maroc / al-Maktaba al-Waṭāniyya li-l-Mamlakat al-Maghribiyya.
Some analytical properties of the matrix related to q-coloured Delannoy numbers
Authors: Mu Lili , Zheng Sai-Nan 
Published: October 2022

AbstractThe $q$-coloured Delannoy numbers $D_{n,k}(q)$ count the number of lattice paths from $(0,\,0)$ to $(n,\,k)$ using steps $(0,\,1)$, $(1,\,0)$ and $(1,\,1)$, among which the $(1,\,1)$ steps are coloured with $q$ colours. The focus of this paper is to study some analytical properties of the polynomial matrix $D(q)=[d_{n,k}(q)]_{n,k\geq 0}=[D_{n-k,k}(q)]_{n,k\geq 0}$, such as the strong $q$-log-concavity of polynomial sequences located in a ray or a transversal line of $D(q)$ and the $q$-total positivity of $D(q)$. We show that the zeros of all row sums $R_n(q)=\sum \nolimits _{k=0}^{n}d_{n,k}(q)$ are in $(-\infty,\, -1)$ and are dense in the corresponding semi-closed interval. We also prove that the zeros of all antidiagonal sums $A_n(q)=\sum \nolimits _{k=0}^{\lfloor n/2 \rfloor }d_{n-k,k}(q)$ are in the interval $(-\infty,\, -1]$ and are dense there.