bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revitalisasi Partisipasi Publik pada Seleksi Jabatan Pimpinan Tinggi (JPT) dalam Sistem Kepegawaian Aparatur Sipil Negara (ASN) di Indonesia
Authors: SUDARWANTO AL SENTOT 
Published: October 2022

<p align="justify">Masyarakat memiliki peran penting pada seleksi jabatan pimpinan tinggi (JPT) dalam sistem kepegawaian aparatur sipil negara (ASN). Selain terkait dengan pelayanan publik, seleksi JPT yang akuntabel, transparan, dan professional merupakan wujud konkret penerapan <em>good governance. </em>Namun, banyaknya pejabat ASN yang terjerat kasus hukum dan banyaknya kepala daerah yang terjerat kasus jual beli jabatan menjadi indikasi minimnya partisipasi publik pada seleksi JPT. </p><p align="justify">Penelitian ini bertujuan untuk menjawab 2 (dua) rumusan masalah, yaitu: (1) Apakah partisipasi publik pada seleksi JPT saat ini sudah optimal? (2) Bagaimana seharusnya konsep revitalisasi partisipasi publik pada seleksi JPT dalam sistem kepegawaian ASN di Indonesia? Jenis penelitian ini adalah penelitian hukum dengan pendekatan <em>statute approach </em>dan <em>c</em><em>onseptual </em><em>approach.</em> Bahan hukum yang digunakan adalah bahan hukum primer dan sekunder. Teknik pengumpulan data dilakukan dengan studi kepustakaan dan observasi dokumen. Analisis yang digunakan adalah analisis yuridis kualitatif.</p><p align="justify">Hasil penelitian menyebutkan bahwa berdasarkan lima spektrum utama partisipasi publik, yaitu: <em>inform, consult, involve, collaborate</em>, dan <em>empower</em>, partisipasi masyarakat pada seleksi JPT saat ini belum optimal. Beberapa upaya revitalisasi partisipasi publik yang dapat dilakukan, yaitu: (1) mewajibkan uji publik bagi calon pejabat pimpinan tinggi pada seleksi JPT; (2) membangun komunikasi positif antara publik dengan panitia seleksi melalui media; dan (3) membangun sistem pengawasan yang terintegrasi antara publik, Komisi ASN, dan Lembaga Ombusman.</p>
Місто Єлисаветград напередодні Першої світової війни: історико-статистичний огляд
Authors: Тимошенко Володимир 
Published: October 2022

Історична урбаністика займає одне із чільних місць у сучасній історичній науці. Вивчення історії міст є запорукою розуміння не лише їхнього розвитку та особливостей життя міського населення, а й дозволяє визначати вплив того чи іншого міста на історичний поступ цілих країв або регіонів. У пропонованій публікації автор узагальнив історико-статистичні дані стосовно адміністративно-територіального, соціально-економічного та культурного становища міста Єлисаветграда напередодні Першої світової війни. Джерельна база дослідження представлена спогадами містян, статистичними щорічниками, адрес-календарями, довідковими, енциклопедичними виданнями та картами 1911-1913 рр. Стаття буде цікавою для фахівців, що займаються проблемами історичної урбаністики, повсякденної історії, мікроісторії та історичного краєзнавства.
Римо-католицькі спільноти Дніпропетровщини у другій половині 1940-х років
Authors: Мосюкова Наталія 
Published: October 2022

У перші повоєнні роки на Дніпропетровщині існували дві римо-католицькі громади — у Дніпропетровську та Дніпродзержинську. Вони відновили свою діяльність (після репресій 1930-х років) ще у часи німецької окупації. Аналіз документів, які є в наявності, але не дають повної інформації, показав, що спільноти були подібні за своєю чисельністю, національною та віковою ознакою.
В умовах певної лібералізації відносин між державою та релігійними організаціями, римо-католики плекали надію на продовження своєї діяльності і після повернення радянської влади на українські землі. Держава ж усіляко перешкоджала повноцінному існуванню парафій, здійснювала фінансовий тиск на них, у результаті спільнота Дніпропетровська була змушена відмовитися від претензій на костел (громада Дніпродзержинська зустрічалася у приватному приміщенні). Спільноти знаходилися під наглядом влади, протягом другої половини 1940-х років тиск на релігійні організації посилювався.
Methods of struggle of the Russian Black Hundreds against Ukrainians in the prisoner-of-war camps in Austria-Hungary and Germany (1914-1917)
Authors: Sribnyak Ihor , Yakovenko Natalia , Matviyenko Viktor 
Published: October 2022

The article is aimed at analyzing forms and methods of struggle of the Russian Black Hundreds against Ukrainian activists of the tsarist army in the prisoner-of-war camps on the territory of Austria-Hungary and Germany (Freistadt, Rastatt, Wetzlar, Salzwedel), being ukrainized at the end of 1914-1915, which was accompanied by the removal of ethnic Russians from those camps.
The research novelty of the article lies in the objective evidence of those factors that initially made it almost impossible to carry out cultural and educational work among captured Ukrainians, as well as the reconstruction of the process of gradual overcoming by the camp residents of their non-acceptance of national liberation slogans and the idea of Ukrainian independence.
Conclusions: It is proved that despite various methods of intimidation (physical violence against Ukrainian activists, destruction of books and magazines, boycott of schools, anonymous leaflets of threatening content, writing down registration numbers of prisoners, etc.), the Black Hundreds did not succeed in preventing the activities of cultural and educational circles created in the camps by the Union for the Liberation of Ukraine (ULU). In a short time, the majority of camp residents joined Ukrainian organizations in the camps, which enabled to minimize the influence of anti-Ukrainian forces. So Ukrainians managed to overcome their centuries-old fear of tsarist despotism, which constrained their ideas and actions with the threat of inevitable punishment. Their desire to gain as much knowledge as possible in conditions of captivity, their readiness to acquire new skills and abilities that they might need during civilian life – suppressed all frightening efforts of the Black Hundreds. It became possible to achieve because of the involvement of captured Ukrainian officers into national organizational activities. Thanks to this, thousands of Ukrainians devoted to the cause of national liberation were brought up in the camps, ready for the armed defense of Ukraine against the Bolshevik invasion.
RETRACTED: Improving the melting performance in a triple-pipe latent heat storage system using hemispherical and quarter-spherical fins with a staggered arrangement
Authors: Abed Azher M. , Mohammed Hayder I. , Patra Indrajit , Mahdi Jasim M. , Arshad Adeel , Sivaraman Ramaswamy , Ibrahem Raed Khalid , Al-Qrimli Fadhil Abbas , Dhahbi Sami , Talebizadehsardari Pouyan 
Published: October 2022

This study aims to evaluate the melting characteristics of a phase change material (PCM) in a latent heat storage system equipped with hemispherical and quarter-spherical fins. A vertical triple-pipe heat exchanger is used as the PCM-based heat storage unit to improve the melting performance compared with a double-pipe system. Furthermore, the fins are arranged in inline and staggered configurations to improve heat transfer performance. For the quarter-spherical fins, both upward and downward directions are examined. The results of the system equipped with novel fins are compared with those without fins. Moreover, a fin is added to the heat exchanger’s base to compensate for the natural convection effect at the bottom of the heat exchanger. Considering similar fin volumes, the results show that the system equipped with four hemispherical fins on the side walls and an added fin on the bottom wall has the best performance compared with the other cases with hemispherical fins. The staggered arrangement of the fins results in a higher heat transfer rate. The downward quarter-spherical fins with a staggered configuration show the highest performance among all the studied cases. Compared with the case without fins, the heat storage rate improves by almost 78% (from 35.6 to 63.5 W), reducing the melting time by 45%.
Case report: Percutaneous adrenal arterial embolization cures resistant hypertension
Authors: Zhou Yaqiong , Wang Dan , Liu Qiting , Hou Jixin , Wang Peijian 
Published: October 2022

BackgroundPrimary aldosteronism is a common cause of resistant hypertension. Patients with primary aldosteronism due to aldosterone-producing adenoma are generally treated with unilateral adrenalectomy or medical therapy. Superselective adrenal arterial embolization is an alternative treatment for patients with unilateral primary aldosteronism.Case summaryWe present a 39-year-old male patient with a 5-year history of primary aldosteronism and secondary hypertension. The patient refused adrenalectomy while accepted pharmacotherapy. Despite taking adequate dose of spironolactone, the patient experienced repeatedly muscle weakness due to hypokalemia and had poor blood pressure control with left ventricular hypertrophy and renal dysfunction. Aldosterone-producing adenoma in the left adrenal gland was confirmed by computerized tomography and adrenal venous sampling. The left middle adrenal artery, which was confirmed to provide the main arterial supply to the aldosterone-producing adenoma, was embolized by injecting 2 ml ethanol. The embolization normalized his blood pressure for up to 3 months and reversed left ventricular hypertrophy.ConclusionSuperselective adrenal arterial embolization could be an alternative treatment for patients with aldosterone-producing adenoma who refuse adrenalectomy.
CodY is modulated by YycF and affects biofilm formation in Staphylococcus aureus
Authors: Wu Shizhou , Qin Boquan , Deng Shu , Liu Yunjie , Zhang Hui , Lei Lei , Feng Guoying 
Published: October 2022

BackgroundStaphylococcus aureus (S. aureus) is the leading cause of various infective diseases, including topical soft tissue infections. The goals of this study were to investigate the roles of YycF and CodY in the regulation of biofilm formation and pathogenicity.MethodsElectrophoretic mobility shift assay (EMSA) was conducted to validate the bound promoter regions of YycF protein. We constructed the codY up-regulated or down-regulated S. aureus mutants. The biofilm biomass was determined by crystal violet microtiter assay and scanning electron microscopy (SEM). Quantitative RT-PCR analysis was used to detect the transcripts of biofilm-related genes. The live and dead cells of S. aureus biofilm were also investigated by confocal laser scanning microscopy (CLSM). We constructed an abscess infection in Sprague Dawley (SD) rat models to determine the effect of CodY on bacterial pathogenicity. We further used the RAW264.7, which were cocultured with S. aureus, to evaluate the effect of CodY on macrophages apoptosis.ResultQuantitative RT-PCR analyses reveled that YycF negatively regulates codY expression. EMSA assays indicated that YycF protein directly binds to the promoter regions of codY gene. Quantitative RT-PCR confirmed the construction of dual- mutant stains codY + ASyycF and codY-ASyycF. The SEM results showed that the biofilm formation in the codY + ASyycF group was sparser than those in the other groups. The crystal violet assays indicated that the codY + ASyycF group formed less biofilms, which was consistent with the immunofluorescence results of the lowest live cell ration in the codY + ASyycF group. The expression levels of biofilm-associated icaA gene were significantly reduced in the codY + strain, indicating codY negatively regulates the biofilm formation. Furthermore, CodY impedes the pathogenicity in a rat-infection model. After cocultured with bacteria or 4-h in vitro, the apoptosis rates of macrophage cells were lowest in the codY + group.ConclusionsYycF negatively regulate the expression of codY. By interaction with codY, YycF could modulate S. aureus biofilm formation via both eDNA- dependent and PIA- dependent pathways, which can be a significant target for antibiofilm. CodY not only impedes the pathogenicity but also has a role on immunoregulation. Thus, the current evidence may provide a supplementary strategy for managing biofilm infections.
Acute effects of combined isometric and plyometric conditioning activities on sports performance and tendon stiffness in female volleyball players
Authors: Kalinowski Rafał , Pisz Anna , Kolinger Dominik , Wilk Michał , Stastny Petr , Krzysztofik Michał 
Published: October 2022

This study aimed to compare the effects of bilateral and unilateral conditioning activities (CA; combined isometric and plyometric) on countermovement jump performance, modified t-agility test, Achilles tendon stiffness and skin surface temperature. Thirteen female semi-professional volleyball players performed two CAs in random order: 1) bilateral isometric half back squats followed by bilateral drop jumps (BI-CA); and 2) unilateral isometric half back squats followed by unilateral drop jumps (UNI-CA). To assess the effects of CAs, countermovement jump, modified t-agility test, Achilles tendon stiffness and skin surface temperature measurements were performed 5 min before and 6 min after the CA. Both CAs significantly increased thigh skin surface temperature from pre- to post-CA (BI-CA, p &lt; 0.001; effect size [ES] = 1.41 and UNI-CA, p = 0.001; ES = 1.39) but none of them influenced modified t-agility test time (interaction: p = 0.338, main effect of time: p = 0.121 and condition: p = 0.819). The countermovement jump height and modified reactive strength index significantly increased from pre-to post-CA during the BI-CA condition (p = 0.003, ES = 0.45, and p = 0.008, ES = 0.48) but not for UNI-CA (p = 0.061, ES = 0.18 and p = 0.065, ES = 0.26). No significant impact has been found for countermovement depth (interaction: p = 0.054, main effect of time: 0.097, and condition: p = 0.41) as well as for contraction time (interaction: p = 0.536, main effect of time: p = 0.224, and condition: p = 0.807). Moreover, stronger and weaker limb CMJ relative peak force significantly decreased from pre-to post-CA (p = 0.014, ES = −0.31, and p = 0.027, ES = −0.26; respectively) during UNI-CA condition but not for BI-CA (p = 0.096, ES = 0.23, and p = 1.41, ES = 0.18). The stronger and weaker limb Achilles tendon stiffness significantly increased from pre-to post-CA during the UNI-CA condition (p = 0.013, ES = 0.60 and p &lt; 0.001, ES = 0.79; respectively) but not for BI-CA (p = 0.66; ES = 0.15 and p = 0.265; ES = 0.42). Furthermore, the post-CA stronger limb Achilles tendon stiffness during the UNI-CA was significantly higher than that noted during the BI-CA (p = 0.006, ES = 0.7). The present study showed that combined isometric and plyometric bilateral CA effectively improved the countermovement jump but did not enhance the t-agility test performance. These findings indicate that exercise combinations could effectively produce a post-activation performance enhancement effect but should replicate the following explosive task as much as possible.
Immune function analysis of LsSd, a transcription factor of the Hippo signaling pathway, in the cigarette beetle Lasioderma serricorne
Authors: Zhang Yue , Yang Jiapeng , Dai Renhuai , Yang Wenjia , Zhang Xiaomin 
Published: October 2022

The Scalloped (Sd) is a transcription factor that regulates organ size control in the Hippo-signaling pathway. Recent studies have showed that Hippo signaling also functions in the innate immune response. Although the Sd gene has been reported in many insects, their immune functions remain unexplored. In this study, the LsSd gene of Lasioderma serricorne, with a complete open reading frame that encodes a protein composed of 402 amino acids was identified. LsSd was predominantly expressed in early pupae. Tissue-specific analyses revealed that the highest concentrations of LsSd were detected in the midgut and brain. At 1–24 h after Escherichia coli infection, LsSd expression increased substantially. However, LsSd expression was downregulated 3–12 h after Staphylococcus aureus infection. RNA interference-mediated silencing of the LsSd transcript resulted in deformed, considerably smaller, and degenerated wings. Meanwhile, LsCycE, LsDiap1, and LsVg, which are involved in cell proliferation and wing development, were drastically reduced when LsSd was depleted. In a survival assay, the LsSd knockdown considerably decreased the susceptibility to S. aureus, a gram-positive bacterium. In addition, knockdown of LsSd remarkably downregulated the transcription of LsCact in response to S. aureus stimulation, while upregulating the expression of five immune-related genes. Our results provide conclusive proof for the important roles of LsSd in the immune response of L. serricorne.
Effectiveness of international virtual training on biorisk management in the context of COVID-19
Authors: Qasmi Shamsul Arfin , Standley Claire , Mohsin Saima , Sarwar Samreen , Malik Laila , Aziz Fatima 
Published: October 2022

IntroductionThe COVID-19 pandemic has resulted in enormous increases in laboratory activities to keep pace with diagnostic testing and research efforts. However, traditional training, technical assistance, and capacity-building approaches were disrupted by the travel and movement restrictions put in place to control the spread of the disease. To address the needs of laboratorians and managers to conduct laboratory activities safely and securely during the pandemic, a highly interactive virtual training (IVT) workshop on biorisk management during COVID-19 was conducted through active learning strategies that connected speakers with participants. The objective of the training was to increase the basic knowledge and standards of biosafety and biosecurity practices, risk assessment, and control measures with reference specifically to the context of the COVID-19 pandemic and apply a rigorous evaluation methodology to assess the effectiveness of the IVT. The training covered a broad range of topics and encompassed national to international guidelines.MethodsParticipants were selected through official channels at the national level, focusing on institutions within Pakistan. The sessions included lectures from international experts in biorisk management concepts, and incorporated poll questions as well as pre- and post-tests and feedback on the speakers' knowledge and presentation skills, to increase interactivity. The pre- and post-test comprised similar multiple-choice questions and provided to every participant to ascertain the impact of the training on awareness and knowledge of biorisk management topics and concepts, and results were compared using paired t-tests. For feedback on the speakers, participants were asked to submit their ratings measured on a five-point Likert scale. The reliability of the Likert scale was estimated using Cronbach's alpha. Analyses were performed using Microsoft Excel and SPSS version 23.ResultsIn total, 52 individuals from different laboratories across Pakistan and Pakistani students from abroad (China) as well participated in at least one session of the IVT. The participants' pre- and post-test scores showed a significant increase in knowledge and awareness (p &lt; 0.001). The obtained Cronbach's alpha score was &gt;0.8, indicating high reliability of the generated feedback on the IVT approach and speakers.ConclusionThe IVT on biosafety and biosecurity in the context of the COVID-19 pandemic proved beneficial for laboratory professionals and could be a useful model to continue in the future for raising awareness and knowledge.
Enactive explorations of children's sensory-motor play and therapeutic handling in physical therapy
Authors: Håkstad Ragnhild B. , Øberg Gunn Kristin , Girolami Gay L. , Dusing Stacey C. 
Published: October 2022

IntroductionIn pediatric physical therapy, there is an ongoing debate about the use of therapeutic handling and its potential effects on motor learning. In this study, we build on enactive theoretical perspectives to explore the role of therapeutic handling in connection to children's sensory-motor play, engagement, and performance during a single physical therapy session.Material and methodsThis is a qualitative study based on video observations of therapy sessions and interviews with 15 physical therapists (PTs) each treating two different children aged 0–3. The authors utilized a framework of co-reviewing, discussing, and reflecting on the sessions. Themes were identified and used to describe the ways by which PTs’ therapeutic handling unfolds, with connections to theories on sensory-motor play and learning, along with enactive perspectives on embodiment, experience, mutual incorporation, and sense-of-agency.ResultsThe characteristics and purposes of therapeutic handling are presented in two main themes: (1) position and support, and (2) directing movement. We found that position and support promoted sensory-motor improvement when the PTs’ handling aligned with the child's play interests and engagements. As part of play, the children used new and additional support surfaces to self-initiate better posture and movement solutions and reach play goals. The PTs’ ways of directing movements varied. To awaken curiosity and induce a child's self-driven motor exploration the PT needs to be subtle, flexible, and precise in the directing of movement. This entails responsiveness to the child's signals and bodily know-how in the placing of hands and direction of pressure to enable the child to actively participate in and eventually self-drive movement.DiscussionTherapeutic handling that is mutually incorporated between PT and child can enrich the child's playing-to-learn-to-move process by providing novelty and facilitating the child's sense-of-agency in the self-initiated exploration and refinement of movement possibilities. In the PTs’ effort to merge therapeutic handling with children's play, the momentum of interaction can open new therapeutic windows of movement experience and learning opportunities.
Hyperkalemic cardiac arrest induced by mannitol administration during craniotomy: A case report and review of the literature
Authors: Zheng Hua , Cao Xueqin , Gao Feng , Li Xinhua , Wan Li , Luo Ailin 
Published: October 2022

IntroductionMannitol is the most widely used hyperosmolar agent during neurosurgical procedures. However, its use can lead to serious hyperkalemia with altered cardiac conduction.Case presentationHere we report a case in which a 40-min cardiac arrest was caused by mannitol-induced hyperkalemia during craniotomy. In addition, we conducted a literature review through a PubMed (MEDLINE) search of the relevant literature published so far. Details of all cases are presented and discussed. The results suggest that male patients or patients with uncontrolled diabetes might be at higher risk to develop this phenomenon. The results also suggest that the high dose and rapid rate of infusion of mannitol might contribute to mannitol-induced hyperkalemia.ConclusionPhysicians should be aware of the existence of mannitol-induced hyperkalemia. Although the mechanism of this complication is not well established, it is prudent to administer mannitol cautiously, especially in patients with uncontrolled diabetes. Continuous electrocardiogram monitoring and frequent measurements of serum electrolytes can help to detect and treat possible life-threatening events induced by mannitol-induced hyperkalemia early.