bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breast Fat Grafting: Comparing Filtration-Centrifugation to Filtration-Washing Fat Processing
Authors: Troell Robert J. 
Published: July 2022

Breast Fat Grafting: Comparing 2 fat processing methods and learned clinical experience. Introduction: Since alloplastic breast implants suffer from numerous potential complications and revision surgery, some practitioners and patients seek alternative treatment. Autologous fat grafting has gained popularity due to its safety and scientific advances yielding increased survival. Materials and Methods: Laboratory evaluation of fat specimens compared to ultrasound-assisted and suction-assisted fat harvesting is presented. The filtration-washing device (PureGraft) versus the filtration-centrifugation device (LipoKit) were compared using both clinical evaluation, laboratory analysis, and diagnostic ultrasound to assess fat thickness before and after surgical placement. Results: The study evaluated 12 women electing breast fat transfer, 6 undergoing PureGraft for processing (mean 29.2 years, Mean BMI 25.5), with 3 of these using suction-assisted harvested fat and 3 using ultrasound-assisted harvested fat. The initial group had 6 patients (mean 28.5 years, Mean BMI 25.1) that had undergone LipoKit fat processing, with 3 of these using suction-assisted harvested fat and 3 using ultrasound-assisted harvested fat. Fat placed ranged between 100 cc and 240 cc per breast in the subcutaneous plane, with a mean of 171.7 cc for LipoKit and 169.2 cc for the PureGraft group. LipoKit fat processing revealed fat grafted breasts to be 40% thicker via diagnostic ultrasound at 10 weeks and 29% thicker at a mean of 7 months and 10 days. The ultrasound-assisted fat harvesting using LipoKit found a mean fat viability of 91.5% compared to 81.8% with PureGraft. Suction-assisted fat harvesting using LipoKit found a mean fat viability of 92.1% compared to 91.5% with PureGraft. Discussion: Our clinical study revealed that in the patient population that elected breast fat grafting as the method of augmentation, there was a high patient satisfaction rate. The filtration-centrifugation system has several advantages: (1) centrifugation forces injuries the larger, more mature, less likely to survive adipocytes (2) the process removes the oil content much more efficiently and in greater quantities than PureGraft, (3) more efficiently and in greater quantities extracts the wetting fluid (4) absence of washing inhibits the removal of lipoaspirate containing growth factors and cytokines, (5) Compacts the fat, and finally (6) Concentrates adipose-derived stem cells and stromal vascular fraction progenitor support cells. There was no difference in fat viability comparing suction-assisted to ultrasound-assisted liposuction fat harvesting. Conclusions: Breast fat grafting using the Filtration-Centrifugation device (LipoKit) revealed superior volume results compared to the Filtration-Washing device (PureGraft), with no difference with suction or ultrasound fat harvesting.
Health Benefits of a 16-Week Whole Food, High Fiber, Plant Predominant Diet among U.S. Employees
Authors: Kelly Rebecca , Hanus Amy , Payne-Foster Pamela , Calhoun Janet , Stout Ron , Sherman Bruce W 
Published: July 2022

Purpose To assess improvements in eating behaviors and health measures among adults participating in a whole food plant predominant diet, Full Plate Living (FPL) program. Design Retrospective, post hoc analysis of self-reported 16-week pre-post participant data obtained over a 3 year program period (2017-19). Setting Wellness offering for employees in Southwest U.S. Subjects Of 6,820 enrollees, 4,477 completed the program, further segmented by generational cohorts. Intervention FPL program materials and weekly online video lessons. Measures Baseline and follow-up measures included eating behaviors, self-perceived health status and energy, body weight, and confidence in healthy eating and weight loss. Analysis Paired t-tests were used to examine changes in eating behaviors and health measures. Mixed-effects models were used to examine whether changes among generational cohorts differed. Results Significant pre-post improvements were demonstrated for all measures, including servings of fruits (1.54 to 2.34), vegetables (2.05 to 2.87), beans (.63 to .99), and weight loss (3.5) ( P < .001). Self-perceived health and energy values, and confidence in making healthy food choices and losing weight improved ( P < .001). Improvements were observed across generational cohorts ( P < .001). Conclusion The FPL healthy eating approach has a beneficial impact on health measures across generational cohorts, and may be an effective addition to lifestyle medicine and corporate wellness offerings. Longer-term program evaluation is warranted.
Evaluation of thiol/disulfide hemostasis and serum Ischemia modified albumin as oxidative stress biomarkers in systemic lupus erythematosus patients: Relationship with major organ involvement and disease activity
Authors: Ermurat Selime , Güler Kazanci Elif , Toka Dilara Isiyel , Ayar Koray , Eren Funda Karakoyunlu , Neşelioğlu Salim 
Published: July 2022

Objectives We aimed to compare thiol/disulfide hemostasis and serum ischemia-modified albumin (IMA) levels, which are indicators of oxidative stress (OS), in patients with systemic lupus erythematosus (SLE), with the healthy control (HC) group and to evaluate the relationship of these parameters with disease activity and major organ involvement. Material-Methods Eighty-four SLE patients and 96 HCs were included in this study. The disease activity of SLE patients was calculated using The Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K). Patients with SLEDAI-2K ≤ 5 were classified as low disease activity (LDA) and those with SLEDAI-2K > 6 as high disease activity (HDA). Thiol/disulfide hemostasis was evaluated using a new automated method and natural thiol (NT), total thiol (TT), disulfide (SS) levels, SS/NT, SS/TT, NT/TT ratios, and serum IMA levels were recorded. Results NT and TT levels were significantly lower (490.11 ± 123.61 vs 536.96 ± 86.05, p = 0.003) (532.56 ± 125.80 vs 565.72 ± 89.82, p = 0.046), SS level (21.22 ± 11.75 vs 13.37 ± 9.31, p < 0.001) was higher, and SS/TT (4.64 ± 2.93 vs 2.52 ± 1.82, p < 0.001) and SS/NT (4.12 ± 2.33 vs 2.35 ± 1.59, p < 0.001) ratios were significantly higher in SLE patients compared to HCs. IMA values were not different between the two groups ( p = 0.920). NT (449.84 ± 136.98 vs 520.32 ± 104.11, p = 0.012) and TT levels (492.01 ± 138.45±562.97 ± 107.09, p = 0.013) were significantly lower and serum IMA levels (0.802 ± 0.089 vs 0.764 ± 0.040, p = 0.023) were significantly higher in SLE patients with HDA than in LDA patients. There was a weak negative correlation between NT (r = −0.284, p=0.009) (r = −0.291, p = 0.007) and TT levels (r = −0.281, p = 0.010) (r = −0.289, p = 0.008) and a weak positive correlation between IMA levels (r = 0.279, p = 0.011) (r = 0.263, p = 0.016) and SLEDAI-2K, and major organ involvement. Conclusion It is thought that thiol/disulfide hemostasis and IMA levels may be used as ideal biomarkers of OS in SLE patients and may reflect the disease activity and major organ involvement.
A Five-Year Retrospective Cohort Study of Survivality and Functional Outcomes of Stroke Patients Following Hospital Admission
Authors: Ghose Manash , Das Rupjyoti , Barua Amit Ranjan , Deka Prasenjit , Barman Aparajita , Borah Nomal Chandra , Chowdhury Nupur , Barman Ananya 
Published: July 2022

Background Stroke is the fourth leading cause of death in India. Data on long-term outcomes of patients with stroke in India are relatively sparse. Objective To document survival and long-term functional outcomes of patients with acute stroke and to assess the measures taken for secondary prevention of stroke. Methods and Material A five-year retrospective cohort study involving 118 patients with acute stroke was conducted. Details about five years’ survival, functional outcomes (modified Rankin Scale [mRS], Barthel index [BI], and Hamilton Depression Rating Scale [HDRS]), and secondary prevention measures were investigated. Results Among the patients, 38.1% were diagnosed with ischemic stroke and 61.8% were diagnosed with hemorrhagic stroke. Hypertension was observed to be the predominant risk factor in a majority of the admitted patients. About 30.5% of patients died in the hospital within zero to four weeks after the index event, while 27.1% died during the follow-up period of five years. Approximately 21.1% of patients experienced a recurrent stroke over the next five years which turned out fatal. The quality of life was seriously affected in 32.4% of survivors. It was seen that 40.5% of survivors were fully independent and 45.9% were able to return to their occupation after five years poststroke. Prevalence of severe and very severe depression was observed in 3.4% and 1.7% of survivors, respectively. The majority of the survivors (93.9%) were aware of the risk of recurrent stroke. Physical activities as measures for the prevention of stroke were undertaken by 60.6% of survivors. Conclusion Effective strategies for secondary prevention and also for long-term survival after stroke should be initiated as early as possible after the onset of the initial stroke. Stroke survivors should be closely monitored for their functional recovery and behavioral and emotional improvement poststroke.
Shaping Mental Health Reform – Key Tasks for an Incoming Government
Authors: Rosenberg Sebastian , Hickie Ian 
Published: July 2022

Objective To describe a recent process by which mental health service sector leaders identified key elements of strategic, systemic and structural mental health reform. These elements could guide an incoming Federal government. Method The paper describes the process undertaken by the Sydney Mental Health Policy Forum between 2019 and 2022. This work generated principles, key domains and finally a set of actions. Results Five immediate actions were identified that are cost neutral or require minimal investment. Five further actions requiring realignment of existing funds and/or new funds were also identified. Conclusions The task of mental health reform in Australia is both large and overdue. Continued investment in fragmented or piecemeal programmes and services will not propel desired change. Reform must facilitate new regional control of planning, funding and responding to community mental health needs. The actions identified by the Forum set out a menu of opportunities to guide reform over the life of the next Parliament, starting now.
Bilateral acute Iris transillumination after COVID-19 pneumonia
Authors: Yüksel Murat , Özdemir Hüseyin Baran , Özdek Şengül , Gürelik Gökhan 
Published: July 2022

Purpose To report the diagnosis, treatment and follow-up of a case of bilateral acute iris transillumination (BAIT) developed after COVID-19 pneumonia. Method Case report. Case A 66-year-old male patient with COVID-19 pneumonia received systemic treatments of favipiravir, prednisolone, moxifloxacin and piperacillin-tazobactam during hospitalization. The patient applied to our clinic with the complaint of blurred vision 20 days after the diagnosis of COVID-19. The best corrected visual acuity (BCVA) was 0.3 in the right eye and 0.5 in the left eye. In the anterior segment examination; ciliary injection, intense pigment dispersion in the anterior chamber, pigment deposits on the lens and iris, 2–3 + cells in the anterior chamber, posterior synechia, and 360 degrees diffuse iris transillumination were observed in both eyes. The pupillary response to light was weak. Bilateral fundus examination were normal. In the anterior chamber sample; HSV, VZV, CMV and Toxoplasma PCR were negative. Bilateral acute iris transillumination (BAIT) diagnosed in the patient and topical 0.1% dexamethasone and topical 1% cyclopentolate were started. In the follow-up, visual acuity increased 1.0 in both eyes, there were no cells in the anterior chamber, and the pigment dispersion was still continuing despite a decrease. Conclusion BAIT, which can usually be seen after upper respiratory tract infections, can also be seen after covid 19 pneumonia and be kept in mind as a possible eye involvement in patients with COVID-19 infection.
Parent and provider satisfaction of telehealth in pediatric surgical subspecialty care: A systematic review
Authors: Gudipudi Rachana , Jungbauer Walter Nicholas , Brennan Emily , Pecha Phayvanh P 
Published: July 2022

Introduction Telehealth is becoming an increasingly common presence in health care, particularly amidst the coronavirus disease 2019 pandemic. We aimed to investigate ways in which telehealth has been implemented in pediatric surgical specialties, as well as the success and satisfaction rates of these interventions. Methods A systematic review was conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines using PubMed, Scopus, and CINAHL databases for telehealth and pediatric surgical specialties on August 20th, 2021. There were 1227 studies screened and 17 studies met final inclusion criteria for patient, parent/guardian, or physician satisfaction measures of a telehealth intervention in the United States. Results Studies implementing telehealth interventions included all major pediatric surgical subspecialties with a total of 2926 patients. Of the 17 studies, common themes were the use of telehealth for synchronous video and/or telephone virtual visits, including comparing virtual visits to in-person clinic visits (nine studies) and postoperative virtual visits (six studies). Telehealth was also used in the perioperative setting to deliver care instructions via mobile application or text message (two studies). Telehealth interventions had a high rate of parent satisfaction (75%–98%), and 57%–75% of parents stated they would choose or prefer virtual appointments in the future, often citing travel and cost savings as benefits. Provider satisfaction was also high with satisfaction scores ranging from 7.5 to 9.4/10. Discussion This systematic review suggests that both parent and physician satisfaction with telehealth in pediatric surgical specialties is generally high. Expanding telehealth applications allow greater access to care, particularly for specialized surgical services which often pose significant costs and travel burdens.
The role of frequency in the acquisition of structured variation: The case of Basque ergativity
Authors: Rodríguez-Ordóñez Itxaso 
Published: July 2022

Aims and objectives: This study examines the extent to which new speakers use the Basque ergative case marking ( –k) in the nominal inflection. I specifically ask whether frequency-based factors (language use and lexical frequency) play a role in its use by also considering speakers’ self-claimed Basque identities. Design/methodology/approach: The spontaneous speech of 39 Basque–Spanish bilinguals was collected by means of sociolinguistic interviews. Participants were self-stratified according to categories of Basque speakerhood ( euskaldunberri “new speaker”; euskaldun “Basque speaker”; euskaldunzahar “native speaker”). We also considered their proficiency, language use, and sex. Data and analysis: In total, 2,755 tokens were extracted for the presence/absence of ergative –k and coded for the following four linguistic factors: verb type, animacy person and number, phonological context, and type of NP. Lexical frequency was operationalized in terms of overall token frequency of lexical verb. Data were analyzed using mixed-effects models in R. Findings and conclusions: Results indicate that despite higher incidence of ergative omissions among new speakers, they show (1) consistent mastery of core internal constraints (verb type, phonological context) and (2) gradual structuring based on lexical frequency effects. These omissions occur in pragmatically structured conditions (topic shift, emphasis, and introducing self in narrative) alongside extensions of –k to unaccusative contexts (focus and topicalization). No independent effects of language use were found. Originality: This study is the first to examine of Basque ergativity among adult Basque speakers, taking also into account discourse factors, lexical frequency, and speakers’ social identities and proficiencies. Significance and implications: First, the mediating effects of lexical frequency are indicative that that sociolinguistic variation is acquired in a piece-meal fashion and that such patterns emerge from discourse as they are used in context. Second, it is argued that the new speakers’ kind of social practices hold key in explaining the reallocation of linguistic constraints in their variable production.
The Recovery Journey and the Rehabilitation Boat - A qualitative study to explore experiences of COVID-19 rehabilitation
Authors: Gerlis Charlotte , Barradell Amy , Gardiner Nikki Y , Chaplin Emma , Goddard Amye , Singh Sally J , Daynes Enya 
Published: July 2022

Introduction There are early data to suggest that a rehabilitation programme can help with on-going symptoms of COVID-19, including breathlessness, exercise limitation and fatigue. As yet, there are no published data to understand patients’ perceived acceptability of a rehabilitation programme for COVID-19. Methods 2 focus groups ( n = 9) and 4 one to one interviews were conducted with participants who attended a rehabilitation program following COVID-19. Interviews were analysed using reflexive thematic analysis with an inductive approach. Results Two overarching themes were generated from the data. The first, The Recovery Journey is sub-divided into five sub-themes of Expectations, Individual and Varied Journeys, Mental and Physical Improvements, Self-values and The Journey Continues. The second overarching theme, The Rehabilitation boat contains five subthemes: Programme Delivery, Safe and Supportive, Validation and Assurance, Shared Reflections and Education. Conclusion A rehabilitation programme for post COVID-19 symptoms was considered to be acceptable and viewed positively in terms of improving physical and mental symptoms. The opportunity to share the experience with others in the same boat was highly valued in the context of an unexpected and potentially lonely COVID-19 recovery.
Mid-term Results of the Treatment of Isolated Dissection of the Celiac Artery: A Comparative Analysis of Endovascular Versus Conservative Therapy
Authors: Shang Tao , Zhou Hua-ji , Wang Yi-shu , Qiu Chenyang , Chen Tian-chi , Sun Jie , Lu Tian , Wu Ziheng , Zhang Hongkun , Li Zhenjiang , Li Dong-lin 
Published: July 2022

Objectives: Endovascular treatment (EVT) is an alternative method used to treat isolated dissection of the celiac artery (IDCA). However, only a few mid-term results have been reported. This study aimed to analyze and compare the outcomes of endovascular and non-operative therapies for IDCA. Methods: Data from a cohort of consecutive IDCA patients enrolled in the study hospital between April 2012 and September 2020 were retrospectively reviewed. Demographic information, imaging features, treatment modalities, and follow-up results of celiac artery remodeling and adverse events were collected and analyzed. Results: A total of 87 patients were enrolled in the study. Stents were deployed in 68 patients, and non-operative treatment (blood pressure control and pain management) was continued in the remaining 19 patients who did not receive stenting; among these 19 patients, EVT failed in 6. The mean follow-up period was 37.3 (range, 10–85 months) and 44.0 (range, 9–80 months) months in the EVT and non-operative groups, respectively. During follow-up, the overall complete remodeling (absence of residual dissection with no false lumen or no intramural thrombus) rate was significantly higher in the EVT group than in the non-operative group (87.3% vs 7.1%, p<0.001). The incomplete remodeling (improved true lumen with malabsorption or partial thrombosis of the false lumen) rate was not significantly different between the EVT and non-operative groups (6.3% vs 14.3%; p=0.2984). Meanwhile, the adverse event-free survival rates were 89.0%, 67.0%, and 67.0% at 1, 3, and 5 years, respectively, in the EVT group compared with 39.7% and 29.8% at 1 and 3 years in the non-operative group (p<0.0001). Conclusions: EVT for IDCA may be considered an effective management option with a favorable clinical success rate, an encouraging complete remodeling rate, and a satisfactory adverse event-free survival rate. However, further evaluation with a long-term follow-up is required. Clinical Impact Endovascular intervention for isolated dissection of the celiac artery has attracted inadequate attention. In this retrospective study with comparative analysis of endovascular versus conservative therapy for isolated dissection of the celiac artery patients, a better complete remodeling rate and a higher adverse event-free survival rate were observed in the endovascular treatment (EVT) group during follow-up, indicating that EVT could be an effective management option for isolated dissection of the celiac artery.
Risk factors in distal interphalangeal joint arthrodesis in the hand: a retrospective study of 173 cases
Authors: Runkel Alexander , Bonaventura Bastian , Sundermann Britta , Zajonc Horst , Eisenhardt Steffen , Leibig Nico 
Published: July 2022

In this retrospective study we aimed to analyse the risk factors for complications after different methods of distal interphalangeal arthrodesis in the hand. Forty-four per cent were treated with K-wire/cerclage fixation, 46% with X-fuse® implants (Stryker GmbH, Selzach, Switzerland) and 10% with headless compression screws (HBS®-screw, KLS Martin Group, Tuttlingen, Germany). The median follow-up was 16 weeks (range 6–224). The overall complication incidence was 44% (minor complications 29% and major 15%). The logistic regression showed that osteoarthritis, revisional arthrodesis and smoking had a negative impact on the total complication incidence. A Cox-regression analysis showed that HBS®-screw arthrodesis was associated with a significantly lower incidence of major complications compared with K-wire/cerclage and X-Fuse®-arthrodesis. Revisional arthrodesis was five times more frequently connected with major complications than primary surgery. Smokers were three times more likely to experience major complications than non-smokers. We conclude that arthrodesis of the distal interphalangeal joint often leads to complications. Risk factors must be kept in mind. Level of evidence: III