bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Vitamin D Levels on Cardiovascular Diseases: A Systematic
Review
Authors: de Macêdo Gonçalves Frota Karoline , de Lima Sousa Paulo Víctor , Nascimento Larisse Monteles , de Oliveira Amanda Ferreira Mesquita , dos Santos Gleyson Moura , da Silva Moura Alana Rafaela , Primo Maísa Guimarães Silva , de Azevedo Paiva Adriana , de Jesus e Silva de Almendra Freitas Betânia , de Carvalho Cecília Maria Resende Gonçalves , do Carmo de Carvalho e Martins Maria 
Published: February 2022

Background:
Cardiovascular diseases (CVDs) are a group of pathologies that involve
heart and blood vessel disorders and are considered the main cause of death in the world. Epidemiological
studies have shown the association between low vitamin D (VD) levels and CVD.
This vitamin, in addition to acting on bone metabolism, plays a role in modulating the cardiovascular
system.

Objective:
The present study assesses the effects of VD levels on CVD through a systematic literature
review.

Method:
For this purpose, the PICO strategy was used to prepare the guiding question, and articles
were searched in the PubMed, Scopus, Science Direct, and Web of Science databases by two
authors independently. To guarantee the quality of the evidence of the articles included in the
review, the Newcastle-Ottawa scale was used. The literature review followed the PRISMA recommendations.

Results:
In this review, 22,757 articles were identified, but only 10 were considered eligible, of
which 70 % are prospective cohorts and 30 % are retrospective cohorts. The study showed that
low 25(OH)D levels correlate with an increased risk of cardiovascular events and death from
CVD, including in patients who had preexisting CVD. However, one article did not demonstrate
this association.

Conclusion:
As a result, VD correlates with cardiovascular events and the risk of death.
Analysis of Novel Variants Associated with Three Human Ovarian Cancer
Cell Lines
Authors: Mekala Venugopala Reddy , Chang Jan-Gowth , Ng Ka-Lok 
Published: February 2022

Background:
Identification of mutations is of great significance in cancer research, as it can contribute to development of therapeutic strategies and prevention of cancer formation. Ovarian cancer is one of the leading cancer-related causes of death in Taiwan. Accumulation of genetic mutations can lead to cancer.

Objective:
We utilized whole-exome sequencing to explore cancer-associated missense variants in three human ovarian cancer cell lines derived from Taiwanese patients.

Methods:
We use (i) cell line whole-exome sequencing data, (ii) 188 patients’ whole-exome sequencing data, and (iii) use of in vitro experiments to verify predicted variant results. We establish an effective analysis workflow for discovery of novel ovarian cancer variants, comprising three steps: (i) use of public databases and in-house hospital data to select novel variants (ii) investigation of protein structural stability caused by genetic mutations, and (iii) use of in vitro experiments to verify predictions.

Results:
Our study enumerated 296 novel variants by imposing specific criteria and using sophisticated bioinformatics tools for further analysis. Eleven and 54 missense novel variants associated with cancerous and non-cancerous genes, respectively, were identified. We show that 13 missense mutations affect the stability of protein 3D structure, while 11 disease-causing novel variants were confirmed by PCR sequencing. Among these, ten variants were predicted to be pathogenic, while the pathogenicity of one was uncertain.

Conclusion:
We confirm that novel variant genes play a crucial role in ovarian cancer patients, with 11 novel variants that may promote progression and development of ovarian cancer.
Application of 68Ga-PSMA-11 PET/CT in the Diagnosis of Prostate Cancer Clinical Relapse
Authors: Diego Regina Paula Soares , Rádis-Baptista Gandhi , Filho Ricardo Vale Albino Oliveira , de Albuquerque Estelita Tinoco Branco , de Castro José Daniel Vieira , dos Santos Katyane Moreira , de Lucena Santos Joelan Ângelo , da Silveira Oliveira Guilherme Freire , de Lucena Santos Poliane Ângelo 
Published: February 2022

Background:
This work aims to present a nuclear medicine imaging service’s data re-garding applying positron emission–computing tomography (PET/CT) scans with the radiopharma-ceutical 68Ga-PSMA-HBED-CC (68Ga-PSMA-11) to diagnose prostate cancer clinical relapse.

Methods:
Eighty patients with a mean age of 68.26 years and an average prostatic-specific antigen blood level of 7.49 ng/ml (lower concentration = 0.17 ng/ml) received 68Ga-PSMA-11 intrave-nously, and full-body images of PET-CT scan were obtained. Of the total of patients admitted to the imaging service, 87.5% were examined for disease’s biochemical recurrence and clinical re-lapse, and 70.0% had a previous radical prostatectomy (RP).

Results:
Of the patients without RP, 95.8% were detected with intra-glandular disease. The 68Ga-PSMA-11 PET/CT imaging results revealed small lesions, even in patients with low blood levels of prostatic-specific antigen, mainly in metastatic cancer cases in lymph nodes and bones.

Conclusion:
The 68Ga-PSMA-11 PET/CT imaging was essential in detecting prostate cancer, with significantly high sensitivity in detecting recurrent cases. Due to its inherent reliability and sensi-tivity, PET/CT scanning with 68Ga-PSMA-11 received an increasing number of medical requests throughout the present follow-up study, confirming the augmented demand for this clinical imaging procedure in the regional medical community.
Role of Natural Plant Products Against Hemagglutinin-esterase (HE) of
Human Coronavirus
Authors: Siddique Yasir Hasan , I. Mantasha , Shahid Mohd. , Naz Falaq 
Published: February 2022

Background:
COVID-19 has spread worldwide and become a great cause of economic and social loss. Due to the non-availability of effective medicine/drug, its control has become a dif-ficult task.

Objective:
In the present study, the effect of some selected natural plant products was studied on the Hemagglutinin-esterase of the human coronavirus by performing molecular docking.

Methods:
Molecular docking study for some selected natural plant products against Hemagglutinin-esterase (HE) of human coronavirus was performed using the HEX 8.0.0 software.

Results:
The free binding energy ranged from -298.14 to -161, with that of curcumin being the highest.

Conclusions:
The results suggest that the natural plant products could act as possible anti-viral agents and may be used as natural therapeutic agents.
RUMO A UMA VISÃO HISTÓRICA, MATERIALISTA E DIALÉTICA.../ HACIA UNA VISIÓN HISTÓRICA, MATERIALISTA Y DIALÉCTICA.../ TOWARDS A HISTORICAL, MATERIALIST AND DIALECTIC VISION...
Authors: Gaxiola Napoleon Count 
Published: February 2022

RUMO A UMA VISÃO HISTÓRICA, MATERIALISTA E DIALÉTICA DO DIREITOResumo: O presente artigo possui como objetivo introduzir as críticas marxistas às noções liberais que formam o arcabouço do Estado, bem como do direito. Para tanto, são esmiuçadas as ideias de Evgeni Pachukanis, em contraposição àquelas de Norberto Bobbio, Carl Schmitt, Hans Kelsen, Herbert Hart e Ronald Dworkin. O direito é explorado, então, não a partir de teorias, mas sim de fatores econômicos, políticos e ideológicos, através dos conceitos de valor de uso, valor de troca, capital, mercadoria, valor, força de trabalho e de forma. TOWARDS A HISTORICAL, MATERIALIST AND DIALECTIC VISION OF LAWAbstract: This paper intends to introduce Marxist critiques to the liberal conceptions that form the structure of State and Law. Eugene Pachukanis are examined comparing those from Norberto Bobbio, Carl Schmitt, Hans Kelsen, Herbert Hart and Ronald Dworkin. Law is approached nor from theories, but from economic, political and ideological notions, through the concepts of value of use, capital, merchandise, value, work force and form. HACIA UNA VISIÓN HISTÓRICA, MATERIALISTA Y DIALÉCTICA DEL DERECHOResumen: Este artículo tiene como objetivo introducir las críticas marxistas de las nociones liberales que forman el marco del Estado, así como de la ley. Con este fin, se examinan las ideas de Evgeni Pachukanis, a diferencia de las de Norberto Bobbio, Carl Schmitt, Hans Kelsen, Herbert Hart y Ronald Dworkin. El Derecho se explora, entonces, no a partir de teorías, sino también de factores económicos, políticos e ideológicos, a través de los conceptos de valor de uso, valor de cambio, capital, mercancía, valor, fuerza laboral y forma.
BAHASA KIASAN, GAYA BUNYI, DAN SAJAK DALAM LIRIK LAGU ALBUM 'PEJANTAN TANGGUH' KARYA SHEILA ON 7
Authors: Wijaya Rahmaditya Khadifa Abdul Rozzaq 
Published: February 2022

This research was aimed at finding and describing the functions of figurative languages, sound styles, and rhymes and in the song lyrics of Sheila on 7 from the album Pejantan Tangguh. This is descriptive-qualitative research whose data are words, phrases, and sentences of the song lyrics in in the album. For collecting the data, Â the researcher applied listening-and-note-taking method whereas for analyzing the data, referential comparative method was employed by determining element selection technique. The results showed that frequent sound styles appears in the lyrics are asonancy and alliteration. This asonancy was used to produce combinations of rhythms that resulted in beautiful effects in the song. Meanwhile, the most dominant figurative language found in the lyrics was metaphor which is followed by personificationm, and hyperbole. All the positions of rhymes, from beginning, middle, to end can also be found in the lyrics.
Confinement effectiveness of CFRP strengthened ultra-high performance concrete cylinders exposed to elevated temperatures
Authors: Abadel Aref A. , Alharbi Yousef R. 
Published: February 2022

Abstract
Fire-related damage is an alarming concern to reinforced concrete (RC) structures throughout their service lives. When exposed to extreme temperatures, concrete can endure severe damage. Given that a complete replacement and/or demolition of fire-damaged structures can be an economic waste, a more viable option for extending the service life of the damaged structures involves repairing or strengthening the damaged members. Due to its more efficient qualities over conventional concrete, the use of concrete, such as ultra-high-performance concrete (UHPC) in the building industry, has dramatically grown in recent years. However, limited information is available about the confinement behavior of the unheated and heated UHPC members, particularly when wrapped with fiber-reinforced polymers (FRP). This paper investigates the effect of carbon fiber reinforced polymer (CFRP) sheet strengthening on the compressive strength of both UHPC and ultra-high-performance fiber reinforced concrete (UHPFRC). In this study, strengthening has been considered for the UHPC cylinders before and after they were subject to an elevated temperature of 400°C, and they were left to cool by air cooling. Six UHPC mixes, which were made without the use of fibers, steel fibers (SF) alone, a hybrid system of SF and polyethylene alcohol (PVA), in addition to a hybrid system of steel, PVA, and polypropylene (PP) fibers were tested. Regarding the plain and various fiber-reinforced UHPC both at room temperature and after being exposed to 400°C, the ultimate compressive strength of CFRP-confined concrete has shown an increase by 25% to 33% and 52% to 61%, respectively compared with the unheated specimens.
Performance evaluation of improved mung bean (Vigna radiata (L.) Wilczek) varieties at low moisture areas East Shewa, Oromia, Ethiopia
Authors: Dinsa Temesgen , Balcha Urgaya , Benya Fayisa , Fufa Mihratu 
Published: February 2022

Mung bean is a useful crop in drier areas and has a good potential for crop rotation and relay cropping with cereals using residual moisture. The experiment was conducted at Adami Tulu Agricultural Research Center (ATARC), Lume and Dugda during 2018 and 2019 with the objective to identify adaptable and high yielder mung bean varieties for East Shewa Zone and similar agro ecologies. Four released mung bean varieties Shewa robit, Beroda, N-26 and Arkebe used as planting material. The experiment was laid down in Randomized Complete Block Design (RCBD) with three replications. The plot size was 1.8m × 2.5 m (4.5 m2) having 6 rows and a spacing of 0.30 m between rows and 50 cm between replication, 1 m between blocks. Data’s like height (cm), number of pods per plant, number of seeds per pod, days to days to flowering, days to maturity, grain yield (kg ha-1), 100 seed weight (g) were collected and analyzed using SAS software. The combined analysis of variance showed that there was significant variation at (P≤0.05 and P≤0.01) among the studied varieties, locations, and year main effect. There were also significant interaction effect on location by year, varieties by year and location by varieties by year for grain yield and other yield components. But non-significant on varieties by location for all traits except plant height and indicated those varieties were performed similarly across the locations. Shewa Robit variety had a higher grain yield (1607.4 kg ha-1) followed by N-26 (1542 kg ha-1) and Beroda (1466.1 kg ha-1). While Arkebe Variety had a lower grain yield (893.4 kg ha-1) as compared with other varieties. Therefore Shewa Robit and N-26 were recommended for the study area and similar agro-ecologies.
Event-related potentials in traffic policemen
Authors: Khaliq Farah , Vaney Neelam , Indora Vipul 
Published: February 2022

Objectives:
Occupational exposure to environmental factors has various adverse effects on health. The traffic policemen are exposed to the higher health risk as they are constantly working in the noisy and polluted environment. Since the job of traffic policemen demands concentration and attention, we planned to study event-related potentials (ERPs) in them to assess this aspect of their cognitive ability.

Materials and Methods:
The present study was conducted on 35 traffic police personnel from the area of East Delhi who were posted at busy traffic intersections for more than 3 years. ERPs were recorded using the oddball paradigm. They had to respond to target stimuli by pressing a button on the response pad with a thumb of their dominant hand.

Results:
The latencies of N100, P200, N200, and P300 waves were not significantly different between controls and subjects. P300 latency was 266.41 ± 39.21 in controls and 254.20 ± 30.84 in subjects (P = 0.15). P300 amplitude was also not significantly different in both groups.

Conclusion:
There are no changes in the latencies of different components of ERP’s of traffic policemen, indicating preserved concentration and attention in our study.
YIELD FORMATION AND GRAIN QUALITY OF WINTER WHEAT IN A TYPICAL GREY DESERT SOILS OF UZBEKISTAN
Authors: Абдурахманов С.О. , Азизов Б.М. , Исроилов Б.А. 
Published: February 2022

Установлено, что в условиях типично сероземных почв орошаемого земледелия более 50% урожая озимой пшеницы формируется за счет минеральных удобрений. Однако в условиях орошения с повышением урожайности наблюдается снижение качества зерна.В опыте самый высокий показатель урожайности зерна 57.0 ц/га наблюдалось при применение высоких доз минеральных удобрений. Прибавка урожая зерна в этом варианте составило 8.0–8.4 ц/га.
It is established that in conditions of typically gray soils of irrigated agriculture more than 50% of the winter wheat crop is formed due to mineral fertilizers. However, in conditions of irrigation with increased yields, there is a decrease in the quality of grain. In experience the highest rate of grain yield 57 c/ha it was observed withthe use of high doses of mineral fertilizers. The yield increase of grain amounted to 8.0–8.4 c/ ha.
ОСОБЕННОСТИ РОСТА, РАЗВИТИЯ, ФОРМИРОВАНИЯ УРОЖАЯ И КАЧЕСТВА КАРТОФЕЛЯ В ЗАВИСИМОСТИ ОТ СИДЕРАТНЫХ КУЛЬТУР
Authors: Остонакулов Т.Э. , Усмонов Н.Н. 
Published: February 2022

В статье изложены результаты изучения роста, развития, формирование урожая, урожайность и семенные качества сортов картофеля после разных сидератных культур. Научно обосновано возможность получения высоких урожаев с хорошими семенными качествами ранних и среднеранних сортов картофеля после лучших сидератных культур.
The article presents the results of a study of growth, development, crop formation, yield and seed quality of potato varieties after different siderate crops. The possibility of obtaining high yields with good seed qualities of early and medium early potato varieties after the best siderate crops is scientifi cally substantiated.
FACTORS CAUSING FORMATION OF METALCOMPOSITION OF SURFACE WATERS IN SOUTHERN BAIKAL REGION
Authors: Семенов М.Ю. , Семенов Ю.М. , Силаев А.В. 
Published: February 2022

Оценена пространственная вариабельность содержания металлов в водах южных притоков Байкала, рассчитан вклад малых рек в формирование состава металлов байкальской воды, рассчитаны коэффициенты водной миграции ряда микроэлементов, включая тяжелые металлы. Составлена схема районирования территории южного Прибайкалья по способности обеспечивать тот или иной состав металлов в водах. Оценена загрязненность поверхностных вод и скорости ассимиляции ими загрязнителей. По данным о содержании металлов в снеговом покрове озера Байкал и дельты реки Селенга выявлены преобладающие антропогенные источники металлов. Установлено, что и в фоновых, и в антропогенных ландшафтах главным фактором формирования состава вод является химический состав их геологических фундаментов. В меньшей степени состав вод зависит от подземных вод регионального стока. В антропогенных ландшафтах состав вод, помимо геологических условий, зависит от интенсивности загрязнения, специфики источников загрязнения и способности водных объектов к самоочищению. Установлено также, что способность вод к самоочищению от конкретного металла зависит от его сродства к органическому веществу вод.
The spatial variability of metal content in the waters of the southern tributaries of Baikal has been estimated, the contribution of small rivers to the formation of the metal composition of Baikal water has been calculated, and the coeffi cients of water migration of a number of trace elements, including heavy metals, have been calculated. A scheme has been drawn up for zoning the territory of Southern Baikal region in terms of its ability to provide some form of metal composition in waters. The contamination of surface waters and their assimilation rates have been assessed. According to the data on the content of metals in the snow cover, the predominant anthropogenic sources of metals have been identifi ed. It has been established that in both background and anthropogenic landscapes the main factor in the formation of water composition is the chemical composition of their geological foundations. To a lesser extent, the composition of the waters depends on the groundwater of the regional drain. In anthropogenic landscapes, the composition of waters, in addition to geological conditions, depends on the intensity of pollution, the specifi city of pollution sources and the ability of water bodies to self-clean. It has also been found that the ability of waters to self-clean from a particular metal depends on its affi nity for the organic matter of waters.
SPECIES DIVERSITY AND NUMBER OF JUVENILE PERCH FISH IN THE LOWER PART OF THE SVIYAZHSKY BAY OF THE KUIBYSHEV RESERVOIR IN 2015–2019
Authors: Андреева Т.В. , Кузнецов В.В. 
Published: February 2022

Рассмотрено видовое разнообразие и численность сеголеток окунеобразных рыб нижней части Свияжского залива Куйбышевского водохранилища за период с 2015 по 2019 гг. Установлено, что за период исследований наиболее многочисленной была молодь окуня. Кроме того, анализируются показатели длина и масса тела сеголеток. Результаты исследования позволяют судить об эффективности воспроизводства рыб в Свияжском заливе Куйбышевского водохранилища и могут использоваться для составления прогнозов уловов.
The species diversity and abundance of fi ngerlings of perch-like fi sh of the lower part of the Sviyazhsky Bay of the Kuibyshev Reservoir for the period from 2015 to 2019 are considered. It has been established that during the period of research, juvenile perch was the most numerous. In addition, the indicators of the length and body weight of yearlings are analyzed. The results of the study make it possible to judge the effi ciency of fi sh reproduction in the Sviyazhsky Bay of the Kuybyshev Reservoir and can be used to make catch forecasts.
SOME FEATURES OF CHANGING IN PHYSICOCHEMICAL PARAMETERS OF SWAMP WATERS WITH SALT POLLUTION (SITE IN VOSTOCHNO-SURGUTSKOYE OIL FIELD, SURGUT LOWLAND OF THE WESTERN SIBERIA)
Authors: Тюрин В.Н. , Кукуричкин Г.М. 
Published: February 2022

В статье рассматривается вопрос об изменении некоторых физико-химических параметров (pH, электропроводности, концентрации хлоридов) под воздействием на верховое болото подтоварных высокоминерализованных вод за 6-летний период наблюдений. Поднята тема о скорости вымывания загрязнителей и причинах изменения экологической обстановки на участке солевого загрязнения.
The article discusses a question of changing in some physicochemical parameters (pH, electrical conductivity, chloride concentration) by impact of highly saline waters on a bog over 6-year observation period. Here is a topic about rate of leaching the pollutants and causes of change in the environmental situation at the salt contamination place.
GEOECOLOGICAL PROBLEMS IN MOSCOW REGION
Authors: Криночкина О.К. 
Published: February 2022

В работе рассмотрены геоэкологические аспекты загрязнения Подмосковья. Особое внимание уделено химическому загрязнению окружающей среды в результате работы автотранспорта на автомагистралях, ведущих к Москве и загрязнению в результате эксплуатации полигонов твердых бытовых отходов (ТКО) и полигонов жидких бытовых отходов. Установлены так же основные причины загрязнения отдельных компонентов окружающей среды. Интересно отметить, что полигоны жидких бытовых отходов рассматриваются не только как источник бактериологического загрязнения почв и грунтов, но и провоцирования негативных геологических процессов, таких как плывуны, образование которых ведет к изменению свойств грунтов в основании зданий и сооружений. Автором предлагаются некоторые рекомендации для решения выше обозначенных проблем.
The article deals with geoecological aspects of pollution in Moscow region. Special attention is given to the review of chemical pollution of the environment near the highways, solid and liquid landfi ll sites. Main reasons of contamination of certain components of environment are established. Liquid landfi ll sites are viewed not only as a source of bacteriological pollution of soil and ground but it provokes negative geological processes, such as quicksand,the formation of which leads to a change in the properties of soils at the base of buildings and structures.The author suggests some recommendations for solving the problems mentioned above.
РАЗВИТИЕ КОМПЛЕКСА КОМПЕНСАЦИОННЫХ МЕРОПРИЯТИЙ ПО СНИЖЕНИЮ НЕГАТИВНОГО ВОЗДЕЙСТВИЯ СТРОИТЕЛЬСТВА ВАНПОРТА БРОНКА НА ЮЖНЫЙ БЕРЕГ НЕВСКОЙ ГУБЫ
Authors: Шилин М.Б. , Бобылев Н.Г. , Ахмад А. , Леднова Ю.А. , Дун С. , Жигульский В.А. 
Published: February 2022

В сравнительном аспекте рассмотрены различные компенсационные мероприятия, направленные на снижение возможных негативных эффектов от строительства аванпорта Бронка на водные и околоводные биологические сообщества геосистемы южного берега Невской губы. Оптимальным меро приятием признается формирование прибрежных охраняемых природных территорий.
From a comparative aspect, we considered various compensation measures aimed at reducing the possible negative effects of port Bronka construction on the aquatic and near-water biological communities of the geosystems on the southern coast of the Neva Bay. The optimal measure is the formation of coastal protected natural areas.
port-building, out-port, compensation measures, aquaculture and reproduction of fi sh stocks, special protected areas, artifi cial biotopes