bluuebunny/crossref_metadata_2025_split huggingface dataset:
L'oral à l'ère du numérique : enseigner et apprendre autrement ?
Authors: Abou Haidar Laura 
Published: January 2022

Cette contribution se propose d'appréhender la manière dont le numérique induit des transformations aussi bien à la manière d'envisager l'oral et de le (re)définir, que de l'enseigner et de l'apprendre. On commencera par rappeler les dimensions les plus impactées par le numérique, par rapport à un dispositif d'enseignement/apprentissage des langues basé sur le présentiel : la temporalité, les modes d'interaction et leurs rituels, la gestion de la plurisensorialité et de la multimodalité, qui sont amenées à s'adapter aux dispositifs numériques utilisés. Néanmoins, le numérique peut constituer une véritable opportunité pour ce qui est de l'oral. La multiplicité des ressources numériques permet de démultiplier les effets bénéfiques de "laboratoire de langue" puisque le smartphone ou l'ordinateur se transforment potentiellement en "cabine individuelle de langue" ; en particulier, le numérique permet un travail particulièrement ciblé, individualisé et intensif, que ce soit sur l'écoute (identifier, discriminer, comparer, comprendre…) ou sur la production (avec des logiciels de plus en plus répandus comme Audacity), ce qui permet d'augmenter les performances de perception et de production des apprenants. Cela va également dans le sens du renforcement de l'autonomisation de l'apprenant et de la diversification des stratégies d'apprentissage. Le numérique permet d'intégrer la dimension gestuelle et kinésique globale, et donne à voir/entendre une multiplicité de ressources d'une grande richesse. L'essor des corpus oraux à visée didactique, et la dynamique créative observée sur la toile, montrent, si besoin était, que l'époque où l'on parlait de la phonétique comme du "parent pauvre de la didactique" est bel et bien révolue.
Explorer les formations comodales en langues
Authors: Othman Sophie 
Published: January 2022

Cet article s'attache à faire un point sur ce que la comodalité peut apporter aux formations en langues et à esquisser quelques lignes directrices essentielles à son succès. En décrivant les spécificités des formations comodales, il insiste sur quelques points-clés : primauté de la réflexion didactique et pédagogique ; définition des modalités de scénarisation, d'encadrement et d'évaluation ; planification rigoureuse permettant, avant tout, de favoriser l'interaction apprenant/enseignant ou entre pairs. Il est nécessaire de réussir à gérer simultanément les deux modes présentiel et distanciel, de favoriser l'interaction et la collaboration entre les participants, d'équilibrer les activités d'apprentissage et d'optimiser le recours aux ressources et aux supports prévus. Quelques scénarios mis en œuvre dans divers contextes serviront d'exemples.
Innate and Adaptive Immunity to Transfused Allogeneic RBCs in Mice Requires MyD88
Authors: Soldatenko Arielle , Hoyt Laura R , Xu Lan , Calabro Samuele , Lewis Steven M , Gallman Antonia E , Hudson Krystalyn E , Stowell Sean R , Luckey Chance J , Zimring James C , Liu Dong , Santhanakrishnan Manjula , Hendrickson Jeanne E , Eisenbarth Stephanie C 
Published: January 2022

Abstract
RBC transfusion therapy is essential for the treatment of anemia. A serious complication of transfusion is the development of non-ABO alloantibodies to polymorphic RBC Ags; yet, mechanisms of alloantibody formation remain unclear. Storage of mouse RBCs before transfusion increases RBC immunogenicity through an unknown mechanism. We previously reported that sterile, stored mouse RBCs activate splenic dendritic cells (DCs), which are required for alloimmunization. Here we transfused mice with allogeneic RBCs to test whether stored RBCs activate pattern recognition receptors (PRRs) on recipient DCs to induce adaptive immunity. TLRs are a class of PRRs that regulate DC activation, which signal through two adapter molecules: MyD88 and TRIF. We show that the inflammatory cytokine response, DC activation and migration, and the subsequent alloantibody response to transfused RBCs require MyD88 but not TRIF, suggesting that a restricted set of PRRs are responsible for sensing RBCs and triggering alloimmunization.
The Kinetics of COVID-19 Vaccine Response in a Community-Vaccinated Population
Authors: Tu Michael K , Chiang Samantha H , Bender Richard A , Wong David T W , Strom Charles M 
Published: January 2022

Abstract
We used a noninvasive electrochemical quantitative assay for IgG Abs to SARS-CoV-2 S1 Ag in saliva to investigate the kinetics of Ab response in a community-based population that had received either the Pfizer or Moderna mRNA-based vaccine. Samples were received from a total of 97 individuals, including a subset of 42 individuals who collected samples twice weekly for 3 mo or longer. In all, &gt;840 samples were collected and analyzed. In all individuals, salivary SARS-CoV-2 S1 IgG Ab levels rose sharply in the 2-wk period after their second vaccination, with peak Ab levels seen at 10–20 d after vaccination. We observed that 20%, 10%, and 2.4% of individuals providing serial samples had a 90%, 95%, and 99% drop, respectively, from peak levels during the duration of monitoring, and in two patients, Abs fell to prevaccination levels (5%). The use of noninvasive quantitative salivary Ab measurement can allow widespread, cost-effective monitoring of vaccine response.
Pulmonary Rehabilitation in Chronic Respiratory Diseases
Authors: Chetambath Ravindran 
Published: January 2022

ABSTRACT
Pulmonary rehabilitation (PR) is a well-established treatment modality in patients with chronic obstructive pulmonary disease. This is intended to improve exercise tolerance and activity-related dyspnea. PR also improves health-related quality of life. There is increasing evidence for similar effects of PR in people with other chronic respiratory diseases such as interstitial lung diseases and bronchiectasis. This review discusses the evidence for PR in chronic respiratory diseases, outlines the essential components of PR in this population, and highlights special considerations for exercise training in people with different diseases. Possible future directions for PR research are explored.
Prevalence for Plantar Fasciitis of Neural Origin in Community-Dwelling Adults
Authors: Thakar Hetakshi Dhananjay , Samson Akhil , Palekar Tushar J. 
Published: January 2022

Introduction:
Plantar fasciitis (PF) is one of the most common causes of heel pain in adults. Common causes of PF include prolonged standing, obesity, flat foot, and nerve entrapment. PF caused due to nerve entrapment is often left unnoticed when making a diagnosis or management for PF. Lateral and medial plantar nerves are the common nerves to get entrapped causing pain and tingling in the foot ultimately leading to PF.

Aims:
This study aimed to come up with the prevalence of PF of neural origin in community-dwelling adults.

Settings and Design:
A cross-sectional study was conducted on fifty patients with PF attending Department of Physiotherapy, Dr. D. Y. Patil College of Physiotherapy, Pimpri, Pune, over a 6 months period.

Subjects and Methods:
Patients were assessed based on their symptoms and whether they meet the criteria for diagnosing the condition as PF. Assessment for classifying PF of neural origin was done using Standard Neurodynamic Testing for Plantar nerves branch of tibial nerve.

Statistical Analysis Used:
Descriptive statistics was presented as frequency percentage.

Results:
The prevalence of neural origin PF among fifty patients was 54%. Forty-eight percent of them were females and 6% were males.

Conclusion:
This study concludes that the burden of PF of Neural Origin is more in Community Dwelling Adults yet goes undiagnosed due to the tendency of following a set battery of physical examination by physiotherapists which does not include neurodynamic tests.
Acute Diabetic Complications and Implications of Glycated Hemoglobin Levels (HbA1c) in the Emergency Department – Experience from a Tertiary Care Centre of South India
Authors: Dhanapal Sudhakar Geratala , Chandy Gina Maryann , Joseph Joshua Vijay , Rajaram Ramgopal Roshan , Madhiyazhagan Mamta , Prabhakar Abhilash Kundavaram Paul 
Published: January 2022

ABSTRACT

Background:
Uncontrolled diabetes leads to acute and chronic complications, both of which present to the emergency department (ED). Glycated hemoglobin (HbA1c) reflects glycemic history. This study was done to determine the correlation between acute diabetic complications and implications of HbA1c levels in ED.

Materials and Methods:
We conducted a prospective observational study between May 2019 and April 2020. Data was collected in a standard datasheet and analysed using Statistical Package for Social Sciences for Windows.

Results:
Our study included a total of 382 (0.5%) patients, among which 56% were male patients. Mean age was 57.9 (standard deviation ± 14.9) years. Based on their hemodynamic stability, majority (n = 291) were triaged as priority one. Acute diabetic complications included hypoglycemia-62% (238/382), diabetic ketoacidosis (DKA) - 26% (98/382) and hyperglycemic hyperosmolar state - 12% (46/382). Most common presenting complaints were unresponsiveness (49.7%) followed by breathing difficulty (31.6%) and fever (24.6%). Random blood sugar level at presentation was <70 mg/Dl in majority (62.3%) of them. Common precipitating factors were poor food intake (51%), infection (30%) and drug noncompliance (29.5%). Three-fourth of the study population was previously diagnosed to have diabetes mellitus and HbA1c >7 was seen in 227 (59%) patients. Bivariate and multivariate logistic regression analysis showed DKA (adjusted odds ratio [OR]: 5.2;95% confidence interval [CI]: 1.39–19.41; P = 0.014), noncompliance to medications (adjusted OR: 3.9; 95% CI: 1.4–10.76; P = 0.009) and poor oral intake (adjusted OR: 0.3; 95% CI: 0.14–0.59; P = 0.001) as independent predictors to have a HbA1c level >7. Approximately half (51.2%) the study population required admission while one patient died in the ED during resuscitation.

Conclusion:
Elderly male population were most commonly involved. Unresponsiveness was the most common presenting complain and hypoglycemia was the most common presenting clinical feature. Majority of the acute diabetic complications were precipitated by poor food intake, infection and noncompliance to medications. Hospital admission was warranted in majority of the study population. HbA1c in the ED is a useful parameter that would help plan further medication at discharge.
Chest computed tomography and pulmonary function analysis of coronavirus disease 2019 survivors in 1 month follow-up period after cure and discharge
Authors: Jiang Li , He Fang , Jiang Hongmei , Gong Haiying , Ding Xuefeng , Duan Xianglin , Pang Min , Huang Yuyan , Jiang Yongjie , Chen Tianwu 
Published: January 2022

OBJECTIVE:
The objective is to explore the chest computed tomography (CT) and pulmonary function findings of coronavirus disease 2019 (COVID-19) survivors 1 month after discharge.

METHODS:
We retrospectively analyzed the chest CT and pulmonary function findings of 158 (COVID-19) survivors who were discharged and followed up at Wuhan Red Cross Hospital from April 9 to May 10, 2020.

RESULTS:
Follow-up chest CT revealed that pulmonary lesions in all patients were clearly absorbed and dissipated. One month after discharge, 125 (79.1%) patients had residual imaging abnormalities, mainly light ground-glass opacities (44.9%) and light patchy shadows (38.6%). Other features included fibrous cord lesions in 90 cases (57.0%), pulmonary nodules in 46 cases (29.1%), pleural thickening in 44 cases (27.8%), and mediastinal lymphadenopathy in 81 cases (51.3%). Among 158 COVID-19 survivors, 124 were tested for pulmonary function. Pulmonary function tests revealed pulmonary function impairment in 10 patients (8.1%), restrictive ventilation dysfunction in 16 (12.9%), and pulmonary diffusion dysfunction in 48 (38.7%). Residual lung lesions and pleural thickening were negatively correlated with DLCO% (P < 0.05).

CONCLUSION:
COVID-19 patients have characteristic findings on chest CT and pulmonary function testing. Identifying these findings is helpful to dynamically monitor the disease prognosis.
CULTURAL IDENTITY AND SYMBOLIC INTERACTIONISM IN KARMA BROWN’S NOVEL “RECIPE FOR A PERFECT WIFE”
Authors: Afiyati Alia , Widyastuti Divya , Pratama Yoga 
Published: January 2022

In a literary work, two characters can be narrated as the attention center that contains the cultural identity from certain generation. Meanwhile, a symbol actually can cause an interaction within characters. This research discusses about cultural identity and symbolic interactionism reflected in a novel. There is a novel entitled “Recipe for a Perfect Wife” by Karma Brown that tells about two female characters that are represented as a housewife from different generation. This research uses descriptive qualitative as the research methodology and content analysis as the method in analyzing the object of the research, a novel entitled “Recipe for a Perfect Wife”. This research also uses the intrinsic approach to analyze the characterization, plot, and setting. This research reveals two kinds of a housewife. They are a housewife and working woman, and a full-housewife. This research finds five cultural identities in the past and present time that is related with a housewife reflected by two female characters in the novel by using cultural identity theory by Stuart Hall. This research also reveals the symbol and memory even three concepts of symbolic interactionism that is mind, self, and society based on symbolic interactionism theory by George Herbert Mead.
KEBIJAKAN DINAS PENDIDIKAN NAGAN RAYA DALAM PENINGKATAN MUTU PENDIDIKAN PADA SEKOLAH DASAR DI KABUPATEN NAGAN RAYA
Authors: Andriansyah T. , Yusrizal Yusrizal , Niswanto Niswanto 
Published: January 2022

The Nagan Raya Education Office is the implementing element of regional autonomy in government affairs in the education sector . The purpose of this research is to determine: program planning, program implementation mechanisms, program evaluation and the obstacles faced by the Education Office in improving the quality of education in primary schools in Nagan Raya District. This study uses a descriptive method with a qualitative approach. The research results show that: (1) The Education Office makes policies in accordance with the results of the work meeting or existing regulations in the Nagan Raya Education Office . (2) The mechanism pelaks anaan program that sealed sanakan by the Education Department Nagan Raya is executed in accordance with the policies made by the Department of Education Nagan Raya or through good management is by way of carrying out the planning, organizing, actuating and controlling . (3) The evaluation carried out by the Nagan Raya Education Office iscarried out comprehensively by focusing on any problems or gaps that occur in each program. (4) The main obstacle that the Nagan Raya Education Office finds in contributing to its education is the Political Will of the Nagan Raya Regent and the deficit in the regional budget.
Abstrak
Dinas Pendidikan Nagan Raya adalah sebagai unsur pelaksana otonomi daerah pada urusan pemerintahan di bidang pendidikan. Tujuan dari penelitian ini adalah untuk mengetahui: perencanaan program, mekanisme pelaksanaan program, evaluasi program dan hambatan-hambatan yang dihadapi oleh Dinas Pendidikan dalam meningkatkan mutu pendidikan pada sekolah dasar di Kabupaten Nagan Raya. Penelitian ini menggunakan metode deskriptif dengan pendekatan kualitatif. Hasil penelitian menunjukan bahwa: (1) Dinas Pendidikan membuat kebijakan sesuai dengan hasil raker atau aturan yang ada di Dinas Pendidikan Nagan Raya. (2) Mekanisme pelaksanaan program yang dilaksanakan oleh Dinas Pendidikan Nagan Raya dijalankan sesuai dengan kebijakan yang dibuat oleh Dinas Pendidikan Nagan Raya atau melalui manajemen yang baik yaitu dengan cara melaksanakan planning, organizing, actuating dan controlling. (3) Evaluasi yang dilakukan Dinas Pendidikan Nagan Raya dilaksanakan dengan komprehensif dengan berfokus pada setiap masalah atau kesenjangan yang terjadi pada setiap program. (4) Hambatan utama yang ditemukan Dinas Pendidikan Nagan Raya dalam memberikan kontribusinya pendidikannya adalah Political Will dari Bupati Nagan Raya serta defisitnya anggaran daerah.
Kata Kunci: Kebijakan Dinas Pendidikan, Mutu, Pendidikan
IMPLEMENTASI USERMANAGER SEBAGAI RADIUS SERVER PADA ROUTER BOARD MIKROTIK RB750GR3
Authors: Zulkarnaen Zulkarnaen 
Published: January 2022

Pada era digital saat ini, kebutuhan terhadap layanan komunikasi data yang semakin meningkat seiring dengan perkembangan teknologi komunikasi yang semakin pesat secara tidak langsung mengubah paradigma bahwa saat ini jarak tidak dapat menghalangi masyarakat dalam beriteraksi baik secara langsung maupun secara virtual. Berbagai opsi konfigurasi sistem operasi pada perangkat jaringan dilakukan sebagai upaya dalam menyajikan layanan akses jaringan yang stabil. Mikrotik dapat diintegrasikan pada jaringan internet rumahan atau jaringan sekala kecil hingga sekala besar. Penelitian ini difokuskan untuk dapat memaksimalkan fungsi pada sistem operasi mikrotik dengan mengintegrasikan usermanager sebagai sistem autentikasi dan radius server sehingga memudahkan adminsitrator jaringan dalam mengelola user yang terkoneksi pada jaringan baik melalui media kabel maupun jaringan wirelles atau wifi. Penelitian ini menggunakan routerboard mikrotik rb750gr3 berfungsi sebagai server hotspot sekaligus sebagai radius server yang diitegrasikan dengan usermanager, hasil ujicoba yang dilakukan, pengunaan mikrotik RB750GR3 yang diintegrasikan dengan package usermanager pada jaringan (NandaHotspot) berjalan dengan baik. Penerapan usermanager sebagai radius server dapat meningkatkan keamanan pada jaringan serta proses pembuatan atau generate user hotspot dapat dilakukan dengan cepat sehingga sangat membantu pihak penyedia jaraingan dalam mengelola dan memonitoring semua user yang terhubung ke jaringan yang dimiliki.
PROGRAM APLIKASI PENGELOLAAN KAS MENGGUNAKAN MICROSOFT VISUAL BASIC 2015 PADA MASJID AL JIHAD BANJARMASIN
Authors: Billy Sabella  , Heldalina Heldalina , Karima Zam Zam  , Veri Julianto  
Published: January 2022

Research purposes. This study aims to determine the proper cash management at Al Jihad Mosque, and to produce a computer-based Cash Management Application Program using Microsoft Visual Basic 2015 as the Front End, and Sql Server 2014 as a back end at the Al Jihad Mosque in Banjarmasin. Theoretical thinking framework. In this study the theoretical framework is analyzing the cash management that runs on the Al Jihad Mosque in Banjarmasin, by analyzing the information needed by management, related functions, accounting documents and records used, and flowcharts. The application program that was developed in the first step was carried out with relations between tables, designing interfaces, and designing outputs. Research result. The results of this study concluded that all cash records are semi-computerized. However, the author recommends using Microsoft Visual Basic 2015 as a Front End, and Sql Server 2014 as a back end so that it can help Al Jihad Mosque to record cash receipts and disbursements quickly and precisely.
Awareness about sexually transmitted diseases in women related to their age, education and income
Authors: Hafeez Tayyaba , Ahmed Yashfeen , Ahmad Maria 
Published: January 2022

Objective: To assess the level of awareness about sexually transmitted diseases in females coming from different age groups and to investigate the role that education and social status may play on their knowledge.
Methods:
Study design: Cross Sectional
Setting: CMH Lahore Gynaecology Out Patient Department
Time frame: June 2019 till July 2019.
Sample size: 337
Inclusion criteria: Patients included in this study presented to the CMH Gynaecology OPD during June to July 2019 and gave an informed consent about participation in the research.
Exclusion criteria: Anyone who did not give consent.
Data collection: Patients were given a hard copy of the questionnaire to fill. Any queries were answered on the spot.
Data Analysis: SPSS version 23.
Results:
Of the 337 patients interviewed, 158 were aged 26-35 years. 71 patients were undergraduates and 99 had completed post graduate studies. 205 patients belonged to families with an income of less than RS.50, 000. 229 females had presented for a routine pregnancy checkup.
244 of the 337 patients had attested to know about STD’s.
The most common source of their knowledge was through TV (142), followed by the internet (137). 251 of the 337 patients were familiar with limited STDs such as AIDS and Hepatitis B.
Conclusion: Age, level of education and income had a profound effect on the knowledge regarding Sexually transmitted diseases amongst the women in Pakistan.
Keywords: Sexually transmitted diseases, sexual and reproductive health, STD’s, STI’s, venereal diseases.
Vonoprozan: potentially new first-line treatment for delayed upper gastrointestinal bleeds following endoscopic procedures? A letter to the editor
Authors: Muhammad Umer  , Syed Wasif Bukhari  
Published: January 2022

Endoscopy nowadays is widely used as a diagnostic and therapeutic tool for various gastrointestinal diseases due to it being less invasive and safer. However, amongst some adverse events is delayed bleeding. The definition of delayed bleeding requires endoscopic hemostasis and/or blood transfusion after at least two days of treatment. (1)
Oesophageal cancer is comparatively more common in Pakistan, being 7th most common malignancy in men and 6th most common in women in Karachi. (2) Oesophageal endoscopic submucosal dissection (E-ESD) employed in the treatment of the above- mentioned cancer has an incidence of delayed bleeding of about 1.3-6.7%. (1) The prevalence of gastric cancer across Pakistan was about 2-18% (3), for which endoscopic submucosal dissection is often used has an incidence of delayed bleeding of 4.7-15.6%. (1) Endoscopic therapy for gastroesophageal varices can also result in delayed bleeding, the incidence of which easily reaches up to 10%. (1)
In a retrospective cohort study of 124,422 patients conducted in Japan, it was found that vonoprazan was more effective in reducing the risk of delayed bleeding compared to omeprazole. (OR= 0.75) (1) Vonoprazan works by competitively inhibiting the potassium-acid channel resulting in strong and sustained acid inhibition. (4) It was also found to have a superior effect in the eradication of H Pylori and an equal effect in acid-related disorders. (5)
In the retrospective study mentioned above, it is also worth noting that the efficacy of vonoprazan was variable with respect to procedures and was most prominent with gastroduodenal endoscopic submucosal dissection (OR=0.70). (1) Other procedures did not elicit any significant difference. In addition, standard/high dose vonoprazan proved to be most efficacious in reducing the risk of delayed bleeding compared with standard/high-dose PPI and low-dose vonoprazan. It was also observed that patients taking anti-thrombotic medications at a higher risk of delayed bleeding also benefited from high-dose vonoprazan. (OR=0.74) (1) The findings above compel the conclusion that high dose vonoprazan should be ideal for reducing the risk of delayed bleeding in patients who have undergone gastroduodenal endoscopic submucosal dissection and/or are on anti-thrombotics.
Though high-dose vonoprazan does look promising, it is imperative that more randomized controlled trials on more diverse populations be conducted to further explore its efficacy and safety as the drug might be a potential first line of therapy.