bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Correlation Between Internet Addiction and Interpersonal Relationship Among Teenagers and College Students Based on Pearson's Correlation Coefficient: A Systematic Review and Meta-Analysis
Authors: Hao Qing-hong , Peng Wei , Wang Jun , Tu Yang , Li Hui , Zhu Tian-min 
Published: March 2022

BackgroundInternet addiction (IA) has become a serious social issue, inducing troubles in interpersonal relationships, which may negatively impact the healthy development of teenagers and college students. Thus, the current research aimed to synthesize the available evidence to clarify the correlation between IA and troubles in interpersonal relationships.MethodWe searched eight electronic databases from inception to December 2020. Study quality was assessed by the Newcastle-Ottawa Scale (NOS), and Agency for Healthcare Research and Quality (AHRQ). We analyzed the data by extracting the Pearson correlation coefficients of each study and converted it into Fisher's Z. Pooled r was conducted by Fisher's Z and standard error (SE). STATA (Version 15.0) software was used for data synthesis.ResultsA total of 10,173 studies were initially identified, and 26 studies (n = 14,638 participants) were retrieved for further analysis. The results indicated that there was a significant positive correlation between IA and interpersonal relationship troubles [0.36 (95% CI 0.35–0.38)]. In addition, there was a positive correlation between IA and different dimensions of interpersonal relationship reflected by troubles with interpersonal conversation, making friends, dealing with people, and heterosexual communication, with the result of [0.26 (95% CI 0.18–0.33)], [0.29 (95% CI 0.20–0.37)], [0.27 (95% CI 0.19–0.34)], [0.22 (0.15–0.30)], respectively. The Egger test suggested that there was no publication bias (P &gt; 0.05).ConclusionIA is positively correlated with troubles in interpersonal relationships. This research will provide new ideas and direction for further intervention, clinical therapy, and policy-making regarding IA to some extent.Systematic Review Registrationhttps://www.crd.york.ac.uk/prospero/, identifier: CRD42020177294.
Rabies Elimination in Rural Kenya: Need for Improved Availability of Human Vaccines, Awareness and Knowledge on Rabies and Its Management Among Healthcare Workers
Authors: Chuchu Veronicah Mbaire , Kitala Philip Mwanzia , Bichanga Philet , Ksee Daniel , Muturi Mathew , Mwatondo Athman , Nasimiyu Carolyne , Maritim Marybeth , Mutono Nyamai , Beyene Tariku J. , Druelles Sophie , Hampson Katie , Thumbi S. M. 
Published: March 2022

BackgroundIn Africa, rabies causes an estimated 24,000 human deaths annually. Mass dog vaccinations coupled with timely post-exposure prophylaxis (PEP) for dog-bite patients are the main interventions to eliminate human rabies deaths. A well-informed healthcare workforce and the availability and accessibility of rabies biologicals at health facilities are critical in reducing rabies deaths. We assessed awareness and knowledge regarding rabies and the management of rabies among healthcare workers, and PEP availability in rural eastern Kenya.MethodologyWe interviewed 73 healthcare workers from 42 healthcare units in 13 wards in Makueni and Kibwezi West sub-counties, Makueni County, Kenya in November 2018. Data on demographics, years of work experience, knowledge of rabies, management of bite and rabies patients, and availability of rabies biologicals were collected and analyzed.ResultsRabies PEP vaccines were available in only 5 (12%) of 42 health facilities. None of the health facilities had rabies immunoglobulins in stock at the time of the study. PEP was primarily administered intramuscularly, with only 11% (n = 8) of the healthcare workers and 17% (7/42) healthcare facilities aware of the dose-sparing intradermal route. Less than a quarter of the healthcare workers were aware of the World Health Organization categorization of bite wounds that guides the use of PEP. Eighteen percent (n = 13) of healthcare workers reported they would administer PEP for category I exposures even though PEP is not recommended for this category of exposure. Only one of six respondents with acute encephalitis consultation considered rabies as a differential diagnosis highlighting the low index of suspicion for rabies.ConclusionThe availability and use of PEP for rabies was sub-optimal. We identified two urgent needs to support rabies elimination programmes: improving availability and access to PEP; and targeted training of the healthcare workers to improve awareness on bite wound management, judicious use of PEP including appropriate risk assessment following bites and the use of the dose-sparing intradermal route in facilities seeing multiple bite patients. Global and domestic funding plan that address these gaps in the human health sector is needed for efficient rabies elimination in Africa.
The Association Between Environmental Perchlorate, Nitrate, and Thiocyanate Exposure and Oral Pain in NHANES
Authors: Yu Jintao , Guo Jiawen , Zhang Hengguo , Cheng Xu 
Published: March 2022

AimTo examine the human exposure to perchlorate, nitrate, and thiocyanate, and their associations with oral pain (OP) in the general population from the U.S.MethodsA total of 13,554 participants were enrolled in the National Health and Nutrition Examination Survey. The urinary perchlorate, nitrate, and thiocyanate were measured using ion chromatography coupled with an electrospray tandem mass spectrometry. The multivariable linear and logistic regressions were performed to explore the associations of the urinary perchlorate, nitrate, and thiocyanate, with the prevalence of oral pain. Restricted cubic splines were used to explore the non-linearity.ResultsThere are 3,129 OP cases. There was a higher urinary level of perchlorate, nitrate, and thiocyanate in OP. We found that urinary thiocyanate was positively associated with OP (odds ratio [OR] = 1.06; [1, 1.13]; p = 0.049). Restricted cubic spines revealed that urinary thiocyanate was in a U-shape association with OP.ConclusionsUrinary thiocyanate was in a U-shape association with OP, suggesting that we should keep the exposure of thiocyanate under a reasonable range.
UV-C Light-Based Surface Disinfection: Analysis of Its Virucidal Efficacy Using a Bacteriophage Model
Authors: Rudhart Stefan A. , Günther Frank , Dapper Laura , Stuck Boris A. , Hoch Stephan 
Published: March 2022

Background: The reprocessing of medical devices has become more complex due to increasing hygiene requirements. Previous studies showed satisfactory bactericidal disinfection effects of UV-C light in rigid and flexible endoscopes. Especially in the context of the current COVID-19 pandemic, virucidal properties are of high importance. In the present study, the virucidal efficacy of UV-C light surface disinfection was analyzed. Methods: MS-2 bacteriophages were applied to the test samples and irradiated by UV-C light using the UV Smart D25 device; unirradiated test samples were used as controls. A dilution series of the samples was mixed with 1 × 108 Escherichia coli and assayed. Results: 8.6 × 1012 pfu could be harvested from the unprocessed test samples. In the control group without UV-C exposure, a remaining contamination of 1.2 × 1012 pfu was detected, resulting in a procedural baseline reduction rate with a LOG10 reduction factor of 0.72. The LOG10 reduction factor was found to be 3.0 after 25 s of UV-C light exposure. After 50 and 75 s of UV-C radiation LOG10 reduction factors 4.2 and 5.9, respectively, were found, with all reductions being statistically significantly different to baseline. Conclusions: The tested UV system seems to provide a significant virucidal effect after a relatively short irradiation time.
GPs’ perspectives regarding their sedentary behaviour and physical activity: a qualitative interview study
Authors: Mayne Richard S , Hart Nigel D , Tully Mark A. , Wilson Jason J , Heron Neil 
Published: March 2022

BackgroundGeneral practice is a highly sedentary occupation, with many GPs spending more than 10.5 hours sitting each workday. This excessive sedentary behaviour and lack of physical activity (PA) is potentially detrimental to the health of GPs, as well as their ability to counsel patients regarding sedentary behaviour and PA. There is a lack of prior research examining the perspectives of GPs regarding their sedentary behaviour and PA.AimTo explore GPs’ perspectives regarding their sedentary behaviour and PA.Design & settingA qualitative interview study of GPs in Northern Ireland.MethodSemi-structured interviews were conducted with a purposive sample of 13 GPs who had previously taken part in a study to objectively measure their levels of sedentary behaviour and PA. Interview transcripts were analysed using deductive thematic analysis. The Theoretical Domains Framework (TDF) was used to facilitate identification of barriers and enablers affecting the ability of GPs to increase their PA.ResultsKey themes were categorised within six theoretical domains (environmental context and resources, social professional role and identity, goals, social influences, knowledge, and intentions) with sub-themes within each domain.ConclusionMost GPs are unhappy with their current levels of sedentary behaviour and PA, and are concerned with how this is affecting their health. Numerous barriers and facilitators were identified affecting the ability of GPs to increase their PA, including working environment, and personal and professional responsibilities, among others. Addressing these could improve the health of GPs and their ability to counsel patients regarding sedentary behaviour and PA.
TINJAUAN HUKUM KEWENANGAN JAKSA DALAM PEMERIKSAAN TAMBAHAN MENURUT ASAS DOMINUS LITIS BERDASARKAN KUHAP
Authors: Firmansyah Alfajri 
Published: March 2022

As a product of the law touted as the great work of the nation
Indonesia, KUHAP introduces a functional differentiation framework, where
The investigation is entirely handed over to the police, while the prosecutor's office
serves only as a public prosecutor and the conduct of the management of judges.
In kuhap itself adheres to the principle of functional differentiation, will
It raises a question as to what is the position of Dominus litis in the KUHAP
when combined with the integrared criminal justice system in it
it contains the principle of functional differentiation. It means when we leave.
From the understanding that Dominus litis is the controller of the case, then the extent to which
stages of the examination process that can be viewed as dominis litis Jaksaan

This question is a consequence, when the relationship between

police with the prosecutor at the investigation stage is only limited to coordination
Functional. KUHAP which adheres to the principles of specialization, differentiation and
complement, not only distinguishing and dividing tasks and authorities,
but also provides a barrier to accountability for the scope of the investigation's duties,
investigation, prosecution and examination at an in-ordered court hearing.
The consequences that arise from the principle of functional differentiation, illustrated from several
the case that led to a free verdict from the Panel of Judges, due to witnesses /
The defendant revoked BAP a quo. Revocation of bap witness/defendant,
due to pressure or engineering of the case at the stage of investigation conducted
by the police as an investigator. The above incident clearly harms the prosecution.
general and the accused himself.
The KIDNEYCODE Program: Diagnostic Yield and Clinical Features of Individuals with CKD
Authors: Lieberman Kenneth V. , Chang Alexander R. , Block Geoffrey A. , Robinson Kristina , Bristow Sara L. , Morales Ana , Mitchell Asia , McCalley Stephen , McKay Jim , Pollak Martin R. , Aradhya Swaroop , Warady Bradley A. 
Published: March 2022

Key Points

Positive findings were detected in 234 out of 859 (27%) individuals associated with Alport syndrome (n=209) and other CKDs.For the 248 individuals who had kidney biopsies, a molecular diagnosis was returned for 49 (20%).These findings support the need to improve access to genetic testing for patients with CKD.

Background
Despite increasing recognition that CKD may have underlyi ng genetic causes, genetic testing remains limited. This study evaluated the diagnostic yield and phenotypic spectrum of CKD in individuals tested through the KIDNEYCODE sponsored genetic testing program.

Methods
Unrelated individuals who received panel testing (17 genes) through the KIDNEYCODE sponsored genetic testing program were included. Individuals had to meet at least one of the following eligibility criteria: eGFR ≤90 ml/min per 1.73m2 and hematuria or a family history of kidney disease; or suspected/biopsy-confirmed Alport syndrome or FSGS in tested individuals or relatives.

Results
Among 859 individuals, 234 (27%) had molecular diagnoses in genes associated with Alport syndrome (n=209), FSGS (n=12), polycystic kidney disease (n=6), and other disorders (n=8). Among those with positive findings in a COL4A gene, the majority were in COL4A5 (n=157, 72 hemizygous male and 85 heterozygous female individuals). A positive family history of CKD, regardless of whether clinical features were reported, was more predictive of a positive finding than was the presence of clinical features alone. For the 248 individuals who had kidney biopsies, a molecular diagnosis was returned for 49 individuals (20%). Most (n=41) individuals had a molecular diagnosis in a COL4A gene, 25 of whom had a previous Alport syndrome clinical diagnosis, and the remaining 16 had previous clinical diagnoses including FSGS (n=2), thin basement membrane disease (n=9), and hematuria (n=1). In total, 491 individuals had a previous clinical diagnosis, 148 (30%) of whom received a molecular diagnosis, the majority (89%, n=131) of which were concordant.

Conclusions
Although skewed to identify individuals with Alport syndrome, these findings support the need to improve access to genetic testing for patients with CKD—particularly in the context of family history of kidney disease, hematuria, and hearing loss.
THIẾT KẾ XÂY DỰNG RƠ LE BẢO VỆ THẤP ÁP KỸ THUẬT SỐ SỬ DỤNG HỆ ĐA VI ĐIỀU KHIỂN
Authors: Hương Nguyễn Thị 
Published: March 2022

Bài báo trình bày việc thiết kế xây dựng rơ le bảo vệ thấp áp kỹ thuật số sử dụng hệ đa vi điều khiển sử dụng trong công nghiệp và dân dụng. Ngoài ra, rơ le thiết kế còn phục vụ công tác giảng dạy cho chuyên ngành kỹ thuật điện và tự động hóa trong các trường khối kỹ thuật nhờ tính năng kết nối được với máy tính PC để thay đổi các thông số của rơ le thông qua phần mềm. Phần cứng của rơ le thiết kế sử dụng hai vi điều khiển Atmega16, là loại vi điều khiển phổ biến trên thị trường. Để nâng cao độ chính xác của rơ le, phần mềm cho rơ le được thiết kế dựa trên các ngắt của vi điều khiển, trong đó có sử dụng các ngắt ngoài để thay đổi giá trị điện áp đặt và thời gian đặt của rơ le, ngắt ADC để đọc điện áp lưới cần bảo vệ. Ngoài ra, một giải pháp quan trọng nữa góp phần nâng cao độ chính xác của rơ le được sử dụng trong bài báo là phương pháp tuyến tính hóa từng đoạn để khắc phục bản chất phi tuyến của máy biến điện áp đầu vào. Các thí nghiệm đối với rơ le kỹ thuật số bảo vệ thấp áp đã thiết kế xây dựng được tiến hành nhằm đánh giá, khẳng định chất lượng của rơ le.
State of Systemic Humoral and Local Immunity in Children with Vasomotor Rhinitis
Authors: Насретдинова М.Т. 
Published: March 2022

Цель. Исследовать состояние системного гуморального и местного иммунитета у детей с вазомоторным ринитом.Материалы и методы. Было исследовано состояние гуморального иммунитета у 71 ребенка в возрасте 4–18 лет с различными формами вазомоторного ринита. Определяли уровень иммуноглобулинов в сыворотке крови и в носовом секрете. Уровень иммуноглобулинов Ig A, M, G в сыворотке крови и в носовых секретах определяли методом простой радиальной иммунодиффузии по Manсinі и соавт.Результаты. У детей младшей возрастной группы выявлено: при аллергической форме вазомоторного ринита отмечалось снижение в сыворотке крови секреторной формы IgA, при нейровегетативной – отсутствие отклонений от нормы уровней секреторных иммуноглобулинов всех трех классов. У детей старшей возрастной группы (старше 10 лет) выявлено снижение содержания sIgA при обеих формах ринита. При аллергической форме ринита у 28 из 36 обследованных отмечено снижение средних значений содержания IgA по сравнению с нормой, у 30 детей содержание IgM было в пределах возрастных норм, у 28 – содержание IgG было выше возрастных норм.Выводы. При длительных вазомоторных расстройствах у детей выявлено снижение местной иммунной защиты слизистой оболочки полости носа (снижение уровня sIgA). Уровень иммуноглобулинов в сыворотке крови имеет прямую корреляционную связь с состоянием местного иммунитета полости носа у детей с вазомоторным ринитом.
Purpose. To study the state of systemic humoral and local immunity in children with vasomotor rhinitis.Materials and methods. The state of humoral immunity was studied in 71 children aged 4–18 years with various forms of vasomotor rhinitis. There was determined the level of immunoglobulins in the blood serum and nasal secretion. The level of immunoglobulins Ig A, M, G in the blood serum and inthe nasal secretions was determined with the method of simple radial immunodiffusion, according to Mancini et al.Results. In children of the younger age group, the following was revealed: in the allergic form, the decrease of the secretory form of IgA; in the neurovegetative form, the absence of abnormalities in the levels of secretory immunoglobulins of all three classes. In children of the older age group (over 10 years old), the decrease of the sIgA content was revealed in both forms of rhinitis. This is apparently due to the duration of the process and the violation of the local synthesis of sIgA. In allergic form of rhinitis, 28 out of 36 patients showed the decrease of the average values of IgA content if compared with the norm; in 30 children, the IgM content was within the age norms; in 28 children, the IgG content was higher than the age norms.Conclusions. In prolonged vasomotor disorders in children, the decrease of the local immune defense of the nasal mucosa (the decrease of the sIgA level) was revealed. The level of immunoglobulins in saliva has a direct correlation with the state of local immunity of the nasal cavity in children with vasomotor rhinitis.
Results of the Last Stage of International Course "ABC" for Training Young Scientists to Conduct Scientific Research in Family Medicine in Ukraine
Authors: Колесник П.О. , Харрис М. , Матюха Л.Ф. , Микита И.В. 
Published: March 2022

Семнадцать молодых ученых приняли участие в двухдневном курсе «Построение вашего исследовательского проекта», цель которого состояла в обучении навыкам качественных исследований и повышении навыков количественных исследований участников. Наибольший рост самооценки исследовательских способностей наблюдался в способности делать обзор литературы, выявлять поддающиеся исследованию клинические вопросы, решать, как лучше всего собирать данные, а также в командной работе, и наибольший рост стадий изменений участников был связан с их намерениями и, что важно, с действиями, которые они предприняли после курса. Это говорит о том, что курс был эффективен не только в повышении квалификации молодых ученых, но и в изменении их исследовательского поведения. К концу курса молодые ученые сотрудничали и имели обратную связь по исследовательским проектам, над которыми они будут работать в течение следующего года.
Seventeen young scientists took part in a two-day "Building your research project" course, which aimed to teach the skills of qualitative research and increase the skills of quantitative research of the participants. The largest increase of self-assessment of research abilities was in the ability to do a literature review, identify researchable clinical questions, decide how to collect data, and in the team work. The biggest increase of the stages of change of participants was connected with theirintentions and, importantly, with the actions that they had taken after the course. This proves that the course was effective not only in increasing the skills of young scientists, but also in changing their research behavior. By the end of the course, the young scientists had collaborated and had feedback on research projects that they would work on over the next year.
STRATEGI PENGEMBANGAN EKONOMI PERDESAAN DI KABUPATEN MINAHASA TENGGARA
Authors: Logor Tirza , Kumenaung Anderson G. , Walewangko Een N. 
Published: March 2022

ABSTRAKPembangunan daerah sebagai bagian integral dari pembangunan nasional tidak bisa dilepaskan dari prinsip otonomi daerah. Faktor yang dapat mempengaruhi indeks desa membangun antara lain adalah jumlah UKM dan IKM yang terdapat didalam satu daerah tesebut. UKM dan IKM juga sangat berperan sebagai roda penggerak pembangunan ekonomi. Selain itu, peran pelaku UKM dipandang sangat penting guna meningkatkan pendapatan perkapita maupun meningkatkan perekonomian suatu daerah. Tujuan penelitian ini adalah untuk mengetahui pengaruh UKM dan IKM secara simultan dan parsial terhadap Indeks Desa Membangun di Kabupaten. Minahasa Tenggara.Jenis penelitian ini adalah jenis penelitian asosiatif dengan menggunakan teknik analisis data regresi linier berganda. Hasil penelitian menunjukkan bahwa (1) Secara Simultan IKM dan UKM berpengaruh signifikan terhadap Indeks Desa Membangun di Kabupaten Minahasa Tenggara, (2) Secara parsial IKM tidak berpengaruh signifikan terhadap Indeks Desa Membangun di Kabupaten Minahasa Tenggara dan (3) Secara parsial UKM berpengaruh signifikan terhadap Indeks Desa Membangun di Kabupaten Minahasa Tenggara Kata kunci: IKM, UKM, IDM ABSTRACTRegional development as an integral part of national development cannot be separated from the principle of regional autonomy. Factors that can affect the index of developing villages include the number of SMEs and IKMs in one area. SMEs and SMEs also play a very important role as a driving force for economic development. In addition, the role of SMEs is seen as very important in order to increase per capita income and improve the economy of a region. The purpose of this study was to determine the effect of SMEs and IKM simultaneously and partially on the Village Building Index in the District. Southeast Minahasa. This type of research is associative research using multiple linear regression data analysis techniques. The results showed that (1) Simultaneously IKM and SMEs had a significant effect on the Developing Village Index in Southeast Minahasa Regency, (2) Partially IKM had no significant effect on the Building Village Index in Southeast Minahasa Regency and (3) Partially SMEs had a significant effect on Index of Developing Villages in Southeast Minahasa Regency Keywords: IKM, SMEs, IDV
Modulation of Fano-like resonance in spherical microbubble cavity for high sensitivity pressure sensing
Authors: Liu Wenyao , Wang Rong , Li Wei , Zhang Bo , Xing Enbo , Zhou Yanru , Sun Peng , Chen Jianjun , Tang Jun , Liu Jun 
Published: March 2022

Abstract
In this paper, we demonstrate a simple scheme to achieve Fano-like and electromagnetically induced transparency (EIT) like resonance by changing the coupling position of a high-Q spherical microbubble cavity with tapered fiber. The evolution processes of the Fano-like and EIT-like spectrums are explored from simulation and experiment, which are in good agreement. And a high sensitivity pressure sensor based on Fano-like resonance is realized. It shows that compared with the slopes of the Lorentz lineshape, Fano-like and EIT-like lineshapes are increased by 2.7 and 20.7 times, respectively. It provides a simple method for ultra-high sensitive sensing.