bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using performance art to promote intergroup prosociality by cultivating the belief that empathy is unlimited
Authors: Hasson Yossi , Amir Einat , Sobol-Sarag Danit , Tamir Maya , Halperin Eran 
Published: December 2022

AbstractEmpathy is important for resolving intergroup conflicts. However, people often tend to feel less empathy toward people who do not belong to their social group (i.e., outgroup members). We propose that this tendency is due, in part, to the belief that empathy is a limited resource. To overcome this issue, we develop an intervention synthesizing psychology and art to increase the belief that empathy is unlimited. In six studies (n = 2118), we find that the more people believe empathy is limited, the less outgroup empathy they experience. Moreover, leading people to believe that empathy is unlimited increase outgroup empathy, leads to greater support for prosocial actions toward outgroup members, and encourages more empathic behaviors toward outgroup members in face-to-face intergroup interactions. These intervention effects are observed across various intergroup contexts involving different ethnic, national, religious, and political groups. Thus, changing beliefs about empathy may improve intergroup relations, and conveying this belief through art may promote social change.
Observation of a robust and active catalyst for hydrogen evolution under high current densities
Authors: Zhang Yudi , Arpino Kathryn E. , Yang Qun , Kikugawa Naoki , Sokolov Dmitry A. , Hicks Clifford W. , Liu Jian , Felser Claudia , Li Guowei 
Published: December 2022

AbstractDespite the fruitful achievements in the development of hydrogen production catalysts with record-breaking performances, there is still a lack of durable catalysts that could work under large current densities (>1000 mA cm−2). Here, we investigated the catalytic behaviors of Sr2RuO4 bulk single crystals. This crystal has demonstrated remarkable activities under the current density of 1000 mA cm−2, which require overpotentials of 182 and 278 mV in 0.5 M H2SO4 and 1 M KOH electrolytes, respectively. These materials are stable for 56 days of continuous testing at a high current density of above 1000 mA cm−2 and then under operating temperatures of 70 °C. The in-situ formation of ferromagnetic Ru clusters at the crystal surface is observed, endowing the single-crystal catalyst with low charge transfer resistance and high wettability for rapid gas bubble removal. These experiments exemplify the potential of designing HER catalysts that work under industrial-scale current density.
Innovative antibacterial electrospun nanofibers mats depending on piezoelectric generation
Authors: Khalil Alaa M. , Hassanin Ahmed H. , El-kaliuoby Mai. I. , Omran Nada , Gamal Mohammed , El-Khatib Ahmed. M. , Kandas Ishac , Shehata Nader 
Published: December 2022

AbstractThis paper introduces a new approach of testing piezoelectric nanofibers as antibacterial mat. In this work, both Polyvinylidene fluoride (PVDF) and PVDF embedded with thermoplastic polyurethane nanofibers are synthesized as nanofibers mat via electrospinning technique. Then, such mat is analyzed as piezoelectric material to generate electric voltage under different mechanical excitations. Furthermore, morphological and chemical characteristics have been operated to prove the existence of beta sheets piezoelectricity of the synthesized nanofibers mats. Then, the synthesized nanofibers surfaces have been cyclically stretched and exposed to bacteria specimen. It has been noticed that the generated voltage and the corresponding localized electric field positively affect the growth of bacteria and reduces the formation of K. penomenue samples bacteria colonies. In addition, the effect of both stretching frequency and pulses numbers have been studied on the bacteria count, growth kinetics, and protein leakage. Our contribution here is to introduce an innovative way of the direct impact of the generated electric field from piezoelectric nanofibers on the reduction of bacteria growth, without depending on traditional anti-bacterial nanoparticles. This work can open a new trend of the usability of piezoelectric nanofibers through masks, filters, and wound curing mats within anti-bacterial biological applications.
The effect of exposure on cattle thyroid after the Fukushima Daiichi nuclear power plant accident
Authors: Horikami Daiki , Sayama Naoya , Sasaki Jun , Kusuno Haruka , Matsuzaki Hiroyuki , Hayashi Akane , Nakamura Tatsuro , Satoh Hiroshi , Natsuhori Masahiro , Okada Keiji , Ito Nobuhiko , Sato Itaru , Murata Takahisa 
Published: December 2022

AbstractNuclear plant accidents can be a risk for thyroid cancer due to iodine radioisotopes. Near the Fukushima Daiichi nuclear power plant, cattle were exposed to radiation after the accident occurred in May 2011. Here we estimated the total radiation exposure to cattle thyroid and its effects on thyroid function. Until October 2016, the estimated external exposure dose in Farm A was 1416 mGy, while internal exposure dose of 131I, 134Cs, and 137Cs were 85, 8.8, and 9.7 mGy in Farm A and 34, 0.2, and 0.3 mGy in Farm B, respectively. The exposed cattle had thyroid with relatively lower weight and lower level of stable iodine, which did not exhibit any pathological findings. Compared with the control, the plasma level of thyroid-stimulating hormone (TSH) was higher in Farm A cattle born before the accident, while the plasma thyroxine (T4) was higher in Farm A cattle born after the accident, suggesting that exposed cattle showed slight hyperactivation of the thyroid gland. In addition, Farm A cattle have higher level of cortisol, one of the anterior pituitary gland-derived hormones. However, we did not observe a causal relationship between the radiation exposure and cattle thyroid.
Anosognosia in hoarding disorder is predicted by alterations in cognitive and inhibitory control
Authors: van Roessel Peter J. , Marzke Cassandra , Varias Andrea D. , Mukunda Pavithra , Asgari Sepehr , Sanchez Catherine , Shen Hanyang , Jo Booil , Gunaydin Lisa A. , Williams Leanne M. , Rodriguez Carolyn I. 
Published: December 2022

AbstractInsight impairment contributes significantly to morbidity in psychiatric disorders. The neurologic concept of anosognosia, reflecting deficits in metacognitive awareness of illness, is increasingly understood as relevant to psychopathology, but has been little explored in psychiatric disorders other than schizophrenia. We explored anosognosia as an aspect of insight impairment inn = 71 individuals with DSM-5 hoarding disorder. We used a standardized clutter severity measure to assess whether individuals with hoarding disorder underreport home clutter levels relative to independent examiners. We then explored whether underreporting, as a proxy for anosognosia, is predicted by clinical or neurocognitive behavioral measures. We found that individuals with hoarding disorder underreport their clutter, and that underreporting is predicted by objective severity of clutter. In ann = 53 subset of participants, we found that underreporting is predicted by altered performance on tests of cognitive control and inhibition, specifically Go/No-Go and Stroop tests. The relation of underreporting to objective clutter, the cardinal symptom of hoarding disorder, suggests that anosognosia may reflect core pathophysiology of the disorder. The neurocognitive predictors of clutter underreporting suggest that anosognosia in hoarding disorder shares a neural basis with metacognitive awareness deficits in other neuropsychiatric disorders and that executive anosognosia may be a transdiagnostic manifestation of psychopathology.
Prospective multicenter study of heart rate variability with ANI monitor as predictor of mortality in critically ill patients with COVID-19
Authors: Aragón-Benedí Cristian , Caballero-Lozada Andres Fabricio , Perez-Calatayud Angel Augusto , Marulanda-Yanten Angela Maria , Oliver-Fornies Pablo , Boselli Emmanuel , De Jonckheere Julien , Bergese Sergio D. ,   ANI-COVID-19 Research Group, Martinez-Ubieto Javier , Pascual-Bellosta Ana , Ortega-Lucea Sonia , Fernandez Juan Pablo Quintero , Camacho Miguel Ángel Martínez , Gaviria-Villarreal Leidy , Mantilla Jorge Mejia , Lopez-Arribas Irene , Centeno-Perez Alejandro , Merino-Ruiz Margarita , Fernandez-Garcia Raquel , Fajardo-Perez Mario , Ledochowski Stanislas 
Published: December 2022

AbstractThe purpose of this study is to demonstrate that the most critically ill patients with COVID-19 have greater autonomic nervous system dysregulation and assessing the heart rate variability, allows us to predict severity and 30-day mortality. This was a multicentre, prospective, cohort study. Patients were divided into two groups depending on the 30-day mortality. The heart rate variability and more specifically the relative parasympathetic activity (ANIm), and the SDNN (Energy), were measured. To predict severity and mortality multivariate analyses of ANIm, Energy, SOFA score, and RASS scales were conducted. 112 patients were collected, the survival group (n = 55) and the deceased group (n = 57). The ANIm value was higher (p = 0.013) and the Energy was lower in the deceased group (p = 0.001); Higher Energy was correlated with higher survival days (p = 0.009), and a limit value of 0.31 s predicted mortalities with a sensitivity of 71.9% and a specificity of 74.5%. Autonomic nervous system and heart rate variability monitoring in critically ill patients with COVID-19 allows for predicting survival days and 30-day mortality through the Energy value. Those patients with greater severity and mortality showed higher sympathetic depletion with a predominance of relative parasympathetic activity.
Calibration of the angle measurement error caused by the industrial reducer performance test instrument torsional deformation
Authors: Yu Zhen , Hao Zongrui 
Published: December 2022

AbstractThe measurement of the stiffness of a precision reducer is essential to estimating the reducer. Since the angular sensor’s measurement results include the angle measurement error caused by the instrument’s torsional deformation, it cannot be used as the actual torsional deformation of the reducer. This paper analyzes the instrument’s torsional deformation characteristics to reduce the angle measurement error. Based on the analysis, a new method of calibrating the angle measurement error based on the improved B-spline curve fitting-gradient descent and particle swarm optimization -radial basis function neural network (IBSCF-GDPSO-RBF) method is proposed. The method can eliminate the angle measurement error caused by the instrument’s torsional deformation. The steps of the IBSCF-GDPSO-RBF method are presented, and the angular measurement error compensation is executed under load conditions. The experiment shows that the instrument deformation caused angle measurement error after compensation is within ± two angular seconds. This paper’s innovation proposes the error calibration method based on the IBSCF-GDPSO-RBF method. It provides a reference for measuring and evaluating the actual torsional rigidity of the Rotary Vector (RV) reducer under any load.
Childhood asthma is associated with development of type 1 diabetes and inflammatory bowel diseases: a Danish nationwide registry study
Authors: Liljendahl Mie Sylow , Sevelsted Astrid , Chawes Bo L. , Stokholm Jakob , Bønnelykke Klaus , Andersen Zorana Jovanovic , Bisgaard Hans 
Published: December 2022

AbstractAsthma and autoimmune disorders might be affected by opposing immune mechanisms, T helper cells type 2 (Th2) and T helper cells type 1 (Th1) immunity, respectively. Knowledge on comorbidity can increase understanding of the underlying etiologies. We aim to examine the association between childhood asthma and subsequent risk of type 1 diabetes (T1D) and inflammatory bowel diseases (IBD) in Danish children. Children of Danish origin born during 1991–1996 were included and childhood asthma, defined as a minimum of two collected prescriptions of inhalation corticosteroids age 5–7 years, was linked to hospitalisations with either T1D or IBD after age 8. Associations between childhood asthma and incidence of T1D and IBD were analysed using sex- and year stratified Cox regression. A total of 366,200 children were included in the study, 4.9% had asthma, which increased the risk of both T1D and IBD, hazard ratios of 1.32 (1.08–1.61) and 1.27 (1.09–1.48). In this large nationwide Danish study, we found that children with asthma have increased risk of developing immune diseases T1D and IBD. This contradicts the Th1 vs Th2 paradigm and points towards shared disease mechanisms and risk factors.
Adaptive changes in sensorimotor processing in patients with acute low back pain
Authors: Boendermaker Bart , Buechler Roman , Michels Lars , Nijs Jo , Coppieters Iris , Hotz-Boendermaker Sabina 
Published: December 2022

AbstractIn low back pain (LBP), primary care and secondary prevention of recurrent and persistent LBP are not always successful. Enhanced understanding of neural mechanisms of sensorimotor processing and pain modulation in patients with acute LBP is mandatory. This explorative fMRI study investigated sensorimotor processing due to mechanosensory stimulation of the lumbar spine. We studied 19 adult patients with acute LBP (< 4 weeks of an acute episode) and 23 healthy controls. On a numeric rating scale, patients reported moderate mean pain intensity of 4.5 out of 10, while LBP-associated disability indicated mild mean disability. The event-related fMRI analysis yielded no between-group differences. However, the computation of functional connectivity resulted in adaptive changes in networks involved in sensorimotor processing in the patient group: Connectivity strength was decreased in the salience and cerebellar networks but increased in the limbic and parahippocampal networks. Timewise, these results indicate that early connectivity changes might reflect adaptive physiological processes in an episode of acute LBP. These findings raise intriguing questions regarding their role in pain persistence and recurrences of LBP, particularly concerning the multiple consequences of acute LBP pain. Advanced understanding of neural mechanisms of processing non-painful mechanosensations in LBP may also improve therapeutic approaches.
Olfactory discrimination and identification as prognostic markers of fitness-to-drive in older drivers
Authors: Touliou Katerina , Maglaveras Nicos , Bekiaris Evangelos 
Published: December 2022

AbstractThe necessity for reliable, standardized and validated fitness to drive assessment tools for older drivers have been highlighted and discussed for over three decades. Existing neuropsychological tests of driving performance are focusing mostly on visuo-spatial attention and executive functioning rather than other senses. Over the last decade, olfactory deterioration has been found to be associated with cognitive decline and predicting transition from mild cognitive impairment to dementia. The AGILE fitness to drive battery is standardized for older drivers. In this study it was adapted to include the olfactory Sniff’ and Stick’s test. The aim was to investigate the value of relevant deficits as predictive markers of driving ability in three driving groups (older drivers with: (a) no impairment (controls), (b) with Mild Cognitive Impairment (MCI) and (c) MCI and other chronic conditions, i.e., comorbidities). So far, no other study has investigated the predictive value of olfactory deficits in driving ability. The findings revealed that discrimination is important for the first year of the examination and as the decline progresses, identification becomes the better olfactory marker. The latter is also evident in the literature. Hence, the results showed that less indicators are required compared to the initial battery. The olfactory markers were dominant over the neuropsychological tests, apart from alertness, for predicting the older driver’s fitness to drive regardless of the presence of cognitive impairment and other chronic conditions.
Adaptive optical phase estimation for real-time sensing of fast-varying signals
Authors: Wang Liu , Xie Fang , Zhang Yong , Xiao Min , Liu Fang 
Published: December 2022

AbstractOptical phase tracking is an important technique for use in high-precision measurement applications, including optical frequency metrology and ground- or space-based gravitational wave observation, and coherent optical communications. When measuring fast-varying real-time signals, the response time limitations of the measurement system’s phase-locked loop cause the best operating point to be mismatched, and the measurement then becomes nonlinear. To make these measurements possible, this work proposes a time delay loop that theoretically enables optimal homodyne detection. When the time delay loop is combined with an extended Kalman filter, the estimated measurement accuracy is improved by 2.4 dB when tracking a fast-varying random signal with a velocity of 107 rad/s. This phase estimation improvement also increases as the interference angle deviates further from the optimal measurement point. The proposed method shows potential for use in real-time sensing and measurement applications.
Phase-adaptive brain stimulation of striatal D1 medium spiny neurons in dopamine-depleted mice
Authors: Kim Youngcho , Jung Dennis , Oya Mayu , Kennedy Morgan , Lence Tomas , Alberico Stephanie L. , Narayanan Nandakumar S. 
Published: December 2022

AbstractBrain rhythms are strongly linked with behavior, and abnormal rhythms can signify pathophysiology. For instance, the basal ganglia exhibit a wide range of low-frequency oscillations during movement, but pathological “beta” rhythms at ~ 20 Hz have been observed in Parkinson’s disease (PD) and in PD animal models. All brain rhythms have a frequency, which describes how often they oscillate, and a phase, which describes the precise time that peaks and troughs of brain rhythms occur. Although frequency has been extensively studied, the relevance of phase is unknown, in part because it is difficult to causally manipulate the instantaneous phase of ongoing brain rhythms. Here, we developed a phase-adaptive, real-time, closed-loop algorithm to deliver optogenetic stimulation at a specific phase with millisecond latency. We combined this Phase-Adaptive Brain STimulation (PABST) approach with cell-type-specific optogenetic methods to stimulate basal ganglia networks in dopamine-depleted mice that model motor aspects of human PD. We focused on striatal medium spiny neurons expressing D1-type dopamine receptors because these neurons can facilitate movement. We report three main results. First, we found that our approach delivered PABST within system latencies of 13 ms. Second, we report that closed-loop stimulation powerfully influenced the spike-field coherence of local brain rhythms within the dorsal striatum. Finally, we found that both 4 Hz PABST and 20 Hz PABST improved movement speed, but we found differences between phase only with 4 Hz PABST. These data provide causal evidence that phase is relevant for brain stimulation, which will allow for more precise, targeted, and individualized brain stimulation. Our findings are applicable to a broad range of preclinical brain stimulation approaches and could also inform circuit-specific neuromodulation treatments for human brain disease.
Multidimensional analyses of the pathomechanism caused by the non-catalytic GNE variant, c.620A>T, in patients with GNE myopathy
Authors: Yoshioka Wakako , Iida Aritoshi , Sonehara Kyuto , Yamamoto Kazuki , Oya Yasushi , Mori-Yoshimura Madoka , Kurashige Takashi , Okubo Mariko , Ogawa Megumu , Matsuda Fumihiko , Higasa Koichiro , Hayashi Shinichiro , Nakamura Harumasa , Sekijima Masakazu , Okada Yukinori , Noguchi Satoru , Nishino Ichizo 
Published: December 2022

AbstractGNE myopathy is a distal myopathy caused by biallelic variants inGNE, which encodes a protein involved in sialic acid biosynthesis. Compound heterozygosity of the second most frequent variant among Japanese GNE myopathy patients,GNEc.620A>T encoding p.D207V, occurs in the expected number of patients; however, homozygotes for this variant are rare; three patients identified while 238 homozygotes are estimated to exist in Japan. The aim of this study was to elucidate the pathomechanism caused by c.620A>T. Identity-by-descent mapping indicated two distinct c.620A>T haplotypes, which were not correlated with age onset or development of myopathy. Patients homozygous for c.620A>T had mildly decreased sialylation, and no additional pathogenic variants inGNEor abnormalities in transcript structure or expression of other genes related to sialic acid biosynthesis in skeletal muscle. Structural modeling of full-length GNE dimers revealed that the variant amino acid localized close to the monomer interface, but far from catalytic sites, suggesting functions in enzymatic product transfer between the epimerase and kinase domains on GNE oligomerization. In conclusion, homozygotes for c.620A>T rarely develop myopathy, while symptoms occur in compound heterozygotes, probably because of mildly decreased sialylation, due to partial defects in oligomerization and product trafficking by the mutated GNE protein.
Associations Between Caregiver Stress and Language Outcomes in Infants With Autistic and Non-Autistic Siblings: An Exploratory Study
Authors: Markfeld Jennifer E. , Feldman Jacob I. , Bordman Samantha L. , Daly Claire , Santapuram Pooja , Humphreys Kathryn L. , Keçeli-Kaysılı Bahar , Woynaroski Tiffany G. 
Published: December 2022

Purpose:
Caregivers of autistic children present with high stress levels, which have been associated with poorer child outcomes in several domains, including language development. However, prior to this study, it was unknown whether elevated caregiver stress was associated with language development in infant siblings of autistic children (Sibs-autism), who are at increased likelihood of receiving a future diagnosis of autism and/or language impairment compared to infant siblings of non-autistic children. This study explored the degree to which, as well as the mechanisms by which, caregiver stress was linked with later language outcomes of Sibs-autism and infant siblings of non-autistic children (Sibs-NA).

Method:
Participants were 50 infants (28 Sibs-autism; 22 Sibs-NA) aged 12–18 months at the first time point in this study (Time 1). Infants were seen again 9 months later, at 21–27 months of age (Time 2). Caregiver stress was measured via a validated self-report measure at Time 1. Caregiver language input, the putative mechanism by which caregiver stress may influence later language outcomes, was collected via two daylong recordings from digital recording (Language ENvironment Analysis) devices worn by the child at this same time point. Child language outcomes were measured via standardized and caregiver report measures at Time 2.

Results:
Several models testing hypothesized indirect effects of caregiver stress on later child language outcomes through caregiver language input were statistically significant. Specifically, significant indirect effects suggest that (a) caregivers with increased stress tend to speak less to their infants, and (b) this reduced language input tends to covary with reduced child language outcomes later in life for Sibs-autism and Sibs-NA.

Conclusions:
This study provides new insights into links between caregiver stress, caregiver language input, and language outcomes in Sibs-autism and Sibs-NA. Further work is necessary to understand how to best support caregivers and optimize the language learning environments for infants.

Supplemental Material:

https://doi.org/10.23641/asha.21714368