bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing Colistin Activity against Colistin-Resistant Escherichia coli through Combination with Alginate Nanoparticles and Small Molecules
Authors: Hazime Noura , Belguesmia Yanath , Kempf Isabelle , Barras Alexandre , Drider Djamel , Boukherroub Rabah 
Published: May 2022

Bacterial resistance to antibiotics has become a major public health problem worldwide, with the yearly number of deaths exceeding 700,000. To face this well-acknowledged threat, new molecules and therapeutic methods are considered. In this context, the application of nanotechnology to fight bacterial infection represents a viable approach and has experienced tremendous developments in the last decades. Escherichia coli (E. coli) is responsible for severe diarrhea, notably in the breeding sector, and especially in pig farming. The resulting infection (named colibacillosis) occurs in young piglets and could lead to important economic losses. Here, we report the design of several new formulations based on colistin loaded on alginate nanoparticles (Alg NPs) in the absence, but also in the presence, of small molecules, such as components of essential oils, polyamines, and lactic acid. These new formulations, which are made by concomitantly binding colistin and small molecules to Alg NPs, were successfully tested against E. coli 184, a strain resistant to colistin. When colistin was associated with Alg NPs, the minimal inhibition concentration (MIC) decreased from 8 to 1 µg/mL. It is notable that when menthol or lactic acid was co-loaded with colistin on Alg NPs, the MIC of colistin drastically decreased, reaching 0.31 or 0.62 µg/mL, respectively. These novel bactericidal formulations, whose innocuity towards eukaryotic HT-29 cells was established in vitro, are presumed to permeabilize the bacterial membrane and provoke the leakage of intracellular proteins. Our findings revealed the potentiating effect of the Alg NPs on colistin, but also of the small molecules mentioned above. Such ecological and economical formulations are easy to produce and could be proposed, after confirmation by in vivo and toxicology tests, as therapeutic strategies to replace fading antibiotics.
Characteristics of Telugu in Middle Dravidian Languages
Authors: S Govindammal 
Published: May 2022

Telugu language can be mentioned next to tamil in terms of antiquity and pronuncication. Telugu is spoken in andhra pradesh and place like south africa in our indian country telugu is the second most widely spoken language after hindi. It is a literary language like tamil. Those who study the reson for the name o this language will think in various ways that the word thrillingam was changed to telugu and it is also believed that the word ‘Tenuge’ which meens sweetness was given knowing that it was telugu. Many grammars have been written in the language from the western country. Northern Scholars, such as nannayapattar have written a number of literatures in this language. The language, which is spoken by more people than tamil is thriving with a variety of creativity. In terms of gender discrimination, telugu can be seen to be different from other dravidian languages the sound and writing script of the telugu language are considered to be the most excellent. The people of chennai who migrated to places like sumatra and java are considered as telugus. That is why the telugu language is still existing as very prominent today.
The Impact of Psychosocial Factors in the Primary Open-Angle Glaucoma Progression
Authors: Любченко М.Ю. , Бибекова Ж.Б. , Шустеров Ю.А. , Ступина Т.А. , Антонович М.Ю. , Базяк Ю.И. , Чеканов Д.М. , Заровный К.В. 
Published: May 2022

Цель. Оценить влияние психосоциальных факторов на прогрессирование первичной открытоугольной глаукомы.Материалы и методы. Ретроспективный анализ историй болезни пациентов, психодиагностическое тестирование и статистический анализ. Были изучены параметры ситуационной и личностной тревожности, семейной напряженности и депрессивных симптомов у пациентов со стабилизированным и нестабилизированным течением первичной открытоугольной глаукомы.Результаты и выводы. Результаты работы показали, что в условиях прогрессирующего течения заболевания представлен повышенный уровень общей семейной тревожности, более высокий уровень личностной и ситуационной тревожности по сравнению с пациентами со стабилизированным течением глаукомы. Уровень депрессивных симптомов у пациентов с нестабилизированным течением глаукомы значительно превышает уровень депрессивных симптомов у пациентов со стабилизированным течением заболевания.
Purpose. To assess the impact of psychosocial factors on the progression of primary open-angle glaucoma.Materials and methods. Analysis of past medical history of patients, psychodiagnostics test and statistical analysis. The parameters of situational and personal anxiety, family tension and depressive symptoms in patients with a stabilized and unsterilized course of primary open-angle glaucoma were studied.Results and conclusions. The results of the work showed that in terms of progressive course of disease an increased level of general family anxiety, a higher level of personal and situational anxiety in comparison with patients with a stabilized course of the glaucomatous process are presented. The level of depressive symptoms in patients with an unsterilized course of glaucoma significantly exceeds the level of depressive symptoms in patients with a stabilized course of the disease.
Moderating Environmental Uncertainty on The Effect of Accounting Knowledge and Accounting Information Systems on the Performance of SMES
Authors: Robiur Rahmat Putra  , Lilis Siti Holisoh 
Published: May 2022

The purpose of this research is to analyze the influence of accounting expertise and accounting information systems on the performance of MSMEs using environmental uncertainty as a moderating variable. The research method used is quantitative with data collection techniques through questionnaires. A total of 97 respondents were collected from various MSMEs in the Lagoa sub-district, Jakarta, Indonesia. The sample was tested for validity and reliability as well as hypothesis testing through the Smart PLS software application. The findings indicated that accounting expertise had no discernible influence on MSMEs' performance. Accounting information systems have a substantial impact on the performance of micro, small, and medium-sized enterprises (MSMEs). Uncertainty in the environment might mitigate the influence of accounting expertise on the performance of MSMEs. Environmental uncertainty may mitigate the influence of accounting information systems on the performance of small and medium-sized businesses.
A Photovoice Study Exploring Deaf Students Experiences during The COVID-19 Pandemic
Authors: Mabruroh Alfina Fadilatul , Gunarhadi Gunarhadi , Widyastono Herry 
Published: May 2022

The Indonesia government through Large-Scale Social Restrictions (PSBB) policy urges distance learning with no exception distance learning for all citizens including for deaf students. Students with disabilities may have been harder to adapt to the distance learning. To explore these potential challenges, this study intended to reveal the exeperince deaf student during study from home using photovoice. The participants of this study were 8 deaf students (4 males and 4 females) from 10,11, and 12nd grades Special School in Surakarta. The study revealed three primary findings. Firstly, deaf students felt more convenient to study with the teacher than the parents. Secondly, they expressed their sadness and tedium during distance learning because of no meeting with friends and their teachers. Thirdly, the interviewed students are dread with the Covid-19 in the other hand they have difficulties to enhanced their communication skills and their competences. As the preliminary study, this study's result would be beneficial for future research. The stakeholder or the researcher can be developing meaningful and joyful learning for helping deaf students adapt the distance learning.
“Notes from England”: Values of Character Education as Junior High School Teaching Materials
Authors: Anindyarini Atikah 
Published: May 2022

This research aims to analyze the values of character education contained in Notes from England and its relevance to teaching materials in Junior High School (Indonesian: Sekolah Menengah Pertama or SMP). This book tells the struggle of Ario Muhammad and Fissilmi Hamida (students coming from Indonesia) in chasing their dream to continue their studies in England. The research data was that of narration and dialogue taken from Notes from England by Ario Muhammad and Fissilmi Hamida, containing character education value. The technique of collecting data used was library study and interview. For data validation, this research employed method triangulation by using document analysis through observing documents and interviewing teachers. Data analysis in this research was carried out using an interactive model of analysis encompassing data reduction, data display, and conclusion drawing. Based on the data analysis on Notes from England, the following conclusions can be drawn: (1) values of character education contained in this book are religiosity, discipline, hard work, creativity, independence, curiosity, friendliness/communicativeness, reading habit, and social care, (2) Notes from England contains many high values of character education, and thereby it is relevant to Literature Teaching materials in the 9th grade of Junior High School (SMP).
Analysis of Digital Learning Models-based MOOCs in Practical Courses to Motivate Students to Learn in Higher Education
Authors: Hidayat Rahmad 
Published: May 2022

This study aims to analyze the need for developing digital knowledge models using MOOCs in practical courses to increase a literacy provocation in advanced education. This disquisition is a type of quantitative descriptive. The population taken in this study were all undergraduate and postgraduate scholars at a state Islamic university in Curup. The slice fashion used is a probability slice with a total sample of 502 scholars from 18 study programs. The system used for data collection is a questionnaire. The instrument used in this studyis a questionnaire on the need for developing a digital knowledge model using MOOCs in practical courses to increase a provocation to learn in advanced education. The results of this study indicate that the instrument used is valid and reliable. The study results also stated that the scholars in this university agreed to develop a digital knowledge model using MOOCs in practical courses with a chance of 75,35%.
Portraying Cendekia Leadership in the Perspective of Ki Hajar Dewantara’s Trilogy
Authors: Arifin Antoni Ludfi , Hermawan Eric 
Published: May 2022

This study aims to describe the Cendekia leadership from the personality perspective of Ki Hajar Dewantara, the father of education in Indonesia. This research is a qualitative study that uses literature study as the method. Seven articles published in the national journal were used as the data of this study and then analyzed using content analysis method. The results of the discussion of cendekia leadership in the perspective of Ki Hajar Dewantara's character from the first philosophy are (1) Ing Ngarso Sung Tuladha; good leadership must behave and speak well and become a role model, discipline, able to be role model for everyone, innovators, protector, educator, honest, wise, and serve wholeheartedly, (2) Ing Madya Mangun Karsa means always help other, motivating and encouraging to work hard, inspiring, have a sense of empathy and sympathy, as well as able to collaborate, (3) Tut Wuri Handayani means that a leader who can encourage his subordinates to be at the forefront of achievement and individuals who are strong in facing obstacles, smart, creative, have a sense of justice, giving freedom to express themselves, and encourage people to be independent, effective, and efficient at work.
Realizing People's Welfare in Economic Globalization, Perspective of the Law on Information and Electronic Transactions
Authors: Nazran Finna , Dewi Siregar Fitri Yanni 
Published: May 2022

Globalization that occurs in the economic field today certainly affects the trade between several countries that are free. This is due to the fact that the use of technology has encouraged rapid business growth, because various information can be presented through long distance relationships and those who wish to conduct transactions do not have to meet face to face, but simply through computer and telecommunications equipment. Utilization of ITE Technology is carried out based on the principles of legal certainty, benefits, prudence, good faith, and freedom to choose technology or technology neutrality. This study aims to determine the development and concept of people's prosperity in economic globalization in Indonesia, with the presence of the ITE Law in creating a just economy. This research uses normative legal research which is descriptive analytical with a qualitative approach to primary data, secondary data and tertiary data which includes the content and structure of positive law. used as a reference in reviewing legal issues that are the object of study. The results of the study indicate that the existence of the ITE Law in creating a just economy at this time has major implications for the development of social life . Economic justice must be understood as a condition where the people control the course of economic activity, through the use of information and technology which is carried out based on the principles of legal certainty, benefits, prudence, good faith, and freedom to choose technology or technology neutrality. This is in line with the goals of the state as stated in the fourth paragraph of the Preamble to the 1945 Constitution.
Morphological Characteristics and Shell Color Of Littoraria pallescens Prosobrancia Molusca From Different Mangrove In Tongkaina Waters, Manado City
Authors: Salawati Vellysa Friendly , Mantiri Desy Maria Helena , Boneka Farnis Bineada , Mamangkey Noldy Gustaf Frans , Warouw Veibe , Kalesaran Ockstan 
Published: May 2022

The purpose of this study was to identify sea slugs L. pallescens taken from two different mangroves, namely Rhizophora mucronata and Avicennia marina in Tongkaina waters, Bunaken District, Manado City based on morphology and anatomy as well as shell color. Identification of mangroves and sea slugs refers to the identification book. The results obtained were L. pallescens species with elongated and tapered morphology at the end of the shell measuring 0.3-2.7 cm. The operculum is purple. The color of the shell obtained was 66.85% consisting of dark colors (black, black, orange, brown and gray spots), occupying the stems and roots of the mangrove, while the light colors (yellow, yellow, dark spots and red) were found to be 33.15%, occupying the leaves and stems of mangroves. The high survival rate of L. pallescens was found in the mangrove roots. This species was found in R. mucronata by 65.26% while in A. marina only 34.74%, this could be caused by differences in the shape of the mangrove roots.Keywords: L. pallescens; Mangrove; Shell color; MorphologyAbstrakTujuan penelitian ini adalah mengindentifikasi siput laut L. pallescens yang diambil dari dua mangrove berbeda yaitu Rhizopora mucronata dan Avicennia marina di perairan Tongkaina, Kecamatan Bunaken, Kota Manado berdasarkan morfologi dan anatomi serta warna cangkang. Identifikasi mangrove dan siput laut merujuk pada buku identifikasi. Hasil penelitian yang diperoleh yaitu spesies L. pallescens dengan bentuk morfologi memanjang dan meruncing, pada bagian ujung cangkang berukuran 0,3-2,7 cm. Operculum berwarna ungu. Warna cangkang yang diperoleh 66,85% yang terdiri dari warna gelap (hitam, hitam bercak orange, coklat dan abu-abu), menempati bagian batang dan akar mangrove sedangkan warna terang (kuning, kuning bercak gelap dan merah) didapat 33,15%, menempati bagian daun dan batang mangrove. Tingginya kelangsungan hidup L. pallescens berada pada bagian akar mangrove. Spesies ini ditemukan pada R. mucronata sebesar 65,26% sedangkan pada A. marina hanya 34,74%, hal ini dapat disebabkan oleh karena perbedaan bentuk akar mangrove. Kata Kunci: L. Pallescens; Mangrove; Warna cangkang; Morfologi
Application of The Admiralty Method to Process Tidal Data in the Waters of The Nasik Strait - Bangka Belitung
Authors: Pasaribu Roberto Patar , Sewiko Roni , Arifin Arifin 
Published: May 2022

Tides are the rise and fall of sea level caused by the attraction of objects in the sky, especially the moon and sun, to the mass of seawater on earth. Tidal research is useful for providing information about the components and types of tides and predicting tides and for mitigating natural disasters. Tidal measurements were carried out in the Nasik Strait, Bangka Belitung using the Valeport 106 tool. Tidal data was processed using the Admiralty Method. The Admiralty method is a method used to calculate tidal harmonic constants from observations of water levels. With this method, it is possible to know the amplitude and phase difference of the tides, the value of the Formzahl number, and the type of tide. From the results of data processing and analysis, the value of the Formzahl number in the waters of the Nasik Strait is 11,454 and the tidal type is a single daily tidal type that only occurs at one high tide and one low tide in one day.Keywords: tides; tidal types; admiralty method; formzahl numberAbstrakPasang surut adalah naik turunnya muka air laut yang disebabkan oleh gaya tarik benda-benda di langit, terutama bulan dan matahari terhadap massa air laut yang ada di bumi. Penelitian pasang surut bermanfaat untuk memberikan informasi mengenai komponen dan tipe pasang surut serta memprediksi pasang surut serta untuk mitigasi bencana alam. Pengukuran pasang surut dilakukan di Perairan Selat Nasik, Bangka Belitung dengan menggunakan alat Valeport 106. Data pasang surut diolah dengan menggunakan Metode Admiralty. Metoda Admiralty merupakan metode yang digunakan menghitung konstanta harmonik pasang surut dari pengamatan ketinggian air. Dengan metoda ini dapat diketahui amplitudo dan beda fase pasang surut, nilai bilangan Formzahl dan tipe pasang surutnya. Dari hasil pengolahan dan analisa data diperoleh nilai bilangan Formzahl di perairan Selat Nasik yaitu 11,454 dan tipe pasang surut adalah tipe pasang surut harian tunggal yang hanya terjadi satu kali pasang dan satu kali surut dalam satu hari.Kata Kunci: pasang surut; tipe pasang surut; metode admiralty; bilangan formzahl
Detección de zonas inactivas en una olla metalúrgica
Authors: Aguilar Corona Alicia , Solorio Díaz Gildardo , Aguilar Ávila Gerardo 
Published: May 2022

La agitación del acero fundido en la olla metalúrgica durante el proceso de refinado secundario es importante ya que asegura la correcta homogeneización de la composición química y térmica. En este trabajo, un modelo de agua de olla metalúrgica agitada con gas es estudiado utilizando la configuración de tapón poroso que se utiliza en el prototipo industrial. Se utilizan dos técnicas de análisis de fluidos para determinar las zonas inactivas o menos agitadas; la técnica de colorimetría y la técnica de velocimetría de imágenes de partículas. La primera permite un análisis global del movimiento del líquido en la olla y la segunda analiza el plano de inyección de aire y el centro de la olla. La identificación de las zonas inactivas permitirá diseñar diferentes configuraciones de tapones porosos, que promuevan un mejor mezclado y consecuentemente la reducción de zonas de baja agitación.
Determination of the electron trap level in Fe-doped GaN by phonon-assisted conduction phenomenon
Authors: Fukuda Hiroki , Nagakubo Akira , Usami Shigeyoshi , Ikeda Masashi , Imanishi Masayuki , Yoshimura Masashi , Mori Yusuke , Adachi Kanta , Ogi Hirotsugu 
Published: May 2022

Abstract
We acoustically measured the energy level for thermally activated conduction (TAC) in high-resistivity Fe-doped GaN using the non-contacting antenna-transmission acoustic-resonance method. The acoustic attenuation takes a maximum at a specific temperature, where the TAC is accelerated with the help of phonon energy. The Debye-type relaxation is thus observed for acoustic attenuation, and its activation energy (0.54

±

0.04 eV) was determined with attenuation measurements at various frequencies and temperatures. This value agrees with the E3 level in GaN, indicating that thermally associated conduction originates from the E3 trap level. We also measured the five independent elastic constants at high temperatures.
Анализ дисперсного состава яичного белка методом микроскопирования
Authors: Соколов Сергей Анатольевич , Яшонков Александр Анатольевич 
Published: May 2022

В содержимом куриного яйца находятся в оптимальном соотношении все питательные вещества, необходимые для развития и поддержания жизни организма человека. Однако, даже при сравнительно непродолжительном хранении свойства яиц заметно изменяются в худшую сторону. Применяемая в настоящее время пастеризация, а также наиболее распространенные способы консервирования жидких яйцепродуктов – сушка и замораживание не обеспечивают микробиологическую стабильность и сохранность полезных свойств продукта в течение его длительного хранения. В рамках исследований установлено, что обработка высоким давлением не только инактивирует микроорганизмы, но и придает новые полезные потребительские характеристики пищевым продуктам. В работе рассмотрены вопросы определения дисперсного состава образцов яичного белка методом микроскопирования. Проведен анализ дисперсного состава яичного белка после действия различного фиксированного давления при комнатной температуре. Определены зависимости площади и среднего диаметра частиц в белке от давления. Предложена математическая модель кинетики денатурации и коагуляции частиц яичного белка после его обработки внешним гидростатическим давлением при комнатной температуре. Установлено, что с повышением давления средний эквивалентный диаметр частиц в образце яичного белка после обработки давлением увеличивается. После действия давления 1009,9 МПа средний эквивалентный диаметр частиц образца увеличивается в 3,799 раза, по сравнению со средним эквивалентным диаметром частиц в яичном белке, обработанном давлением 220,4 МПа.