bluuebunny/crossref_metadata_2025_split huggingface dataset:
mercado del gas natural: visión general y análisis del mercado europeo
Authors: Martínez Farreres Raquel , Merino García Pedro Antonio 
Published: January 2022

En este artículo se pretende analizar el estado del mercado del gas global, con especial atención al caso del mercado europeo. Se analizará el contexto no solo energético, sino también geopolítico, que han dado como resultado la situación actual: un mercado de gas tensionado y desequilibrado cotizando a precios astronómicos. Finalmente, se incluirá un resumen de las previsiones a corto y largo plazo proporcionadas por la Agencia Internacional de la Energía (AIE) en su último reporte World Energy Outlook (WEO), con el ánimo de esclarecer el papel que se espera que desempeñe el gas natural en el proceso de transición de los modelos energéticos.
The impact of weather risks on the yield of corn for grain in the Rostov region
Authors: Kupriyanova Svetlana , Vlasov Mikhail 
Published: January 2022

One of the reasons for the volatility of agricultural production is poorly predictable weather fluctuations that affect the food security of our country and are a serious problem for agricultural producers.
Therefore, it is necessary to develop, justify and use measures that contribute to increasing the stability of agricultural crop yields throughout the territory of agricultural lands.
The object of research was the yield of corn for grain and weather conditions during its growing season in the Rostov region. The purpose of the study was to analyze the impact on the stability of corn yield on grain of two main factors: natural and climatic changes represented by fluctuations in moisture supply, both interannual and during the growing season of corn for grain, and human economic activity considered in the aspect of reclamation measures, as well as the development and formulation of proposals to improve this stability.
The main factors influencing the sustainable development of agricultural production as a whole are identified by the methods of system analysis and a scheme of relations in the agroindustrial complex is constructed, and the dependences of the corn yield on grain on the experimental fields of the Biryuchekut vegetable breeding experimental station are determined by the methods of statistical analysis –the branch of the Federal State Budgetary Scientific Institution ≪Federal Scientific Center of Vegetable Growing≫ depends on the amounts of precipitation and temperatures during the growing season, on the basis of which the main directions of land reclamation are formulated that allow optimal use of the agricultural opportunities of the land fund.
The paper notes the connection of fluctuations in the yield of corn for grain with the heterogeneity of weather and climatic conditions and the results of human economic activity depending on the level of scientific and technical development in the agricultural sector, as well as with complex solutions to environmental management problems consisting in the rational use of natural resources and the use of various types of land reclamation. It was found that in the period from 2000 to 2019, depending on the amount of precipitation, the yield of corn on the bogar at the representative object varied from 11.8 to 39.5 c/ha, that is, by more than 3.3 times, whereas during irrigation in these years of observation, the yield was from 125.2 to 138 c/ha, respectively, that is, yield fluctuations did not exceed 10 %, irrigation of corn crops in acute arid years increased the yield by 8.6 times, in dry years –by 82.2 %, in favorable –by 71.7 %, and this indicates that in order to obtain a high yield of corn for grain, irrigation should be used not only in dry years, but also in years when 350–00 mm of precipitation falls during the growing season.
Muslim Teenagers and Their Understanding of Fardu Ain Knowledge
Authors: Embong Abdul Mutalib , Haji Abd. Rahman Asyraf , Chua Nurul Ain , Zakaria Muhamad Khairul , Embong Abdul Hanis , Dollah@Abdullah Aisyah , Hanafi Nurhazliyana , Ismail Ismar Liza Mahani , Ismail Radhiah 
Published: January 2022

Being a Muslim and a teenager is not easy especially in this modern world. They need to struggle with a flux of developmental, social, cultural, and religious factors that can propel them toward negative attitudes and behaviour. It can impede their life and faith. As Muslims, teenagers are adhered to the teachings is Fardu Ain. It refers to obligatory acts that each Muslim must perform. This paper explores the Fardu Ain level among the 1232 Muslim teenagers focusing on prayers or Solat. The domains of demography are taken into account in this paper. It is found that most of the Muslim teenagers have a good understanding of Fardu Ain, with a mean level of 3.92. In terms of genders, female teenagers have a slightly better understanding of Fardu Ain with a mean score of 4.4087 than their male counterparts, which stands at 4.3337 of the mean score. From the education perspective, the results show the three levels of education give almost the same significant results within the range between 4.3219 to 4.3952 of mean scores. As a whole, the study signifies that Muslim teenagers prioritise remembering God, which is a hallmark of Islam. They also understand prayers cleanse their mind and make them a better person before the emotionally and psychologically benefits.
Elemen Silang Budaya Bagi Penghasilan Motif Baharu Dalam Seni Islam Tempatan
Authors: Nik Abdullah Nik Narimah , Mohamad Nasri Nurfaradilla , Harun Mohd Fauzi , Mat Alim Muliyati , Johari Mohd Hisham 
Published: January 2022

Cross-cultural application efforts are not only focused on physical activity in communities but can be applied through a variety of mediums. Islamic Art is broad and needs to be developed and enriched with creativity. Islamic art still maintains the same way of presentation and there are no new transformations. This study will identify the elements of cross-cultural art that are possible to generate new ideas for the design of Islamic Art motifs. The cross-cultural component in this study is the cultural basis of Malaysia's three main ethnic groups. The study of creating cross-cultural-based motifs are limited. There are no new addition and creativity in the field of Islamic Art. This study aims to identify the art elements of cross-culture that can be used as inspiration for motif design and propose a new possible cross-cultural Islamic Art motif design. The design and development approach underpinned by the ADDIE model was used in this study. Cross-cultural elements such as symbols, images and colours that do not conflict with the core of Islamic art can generate high creativity and inspire innovation in producing Islamic Art motifs. In conclusion, the cross-cultural art element can be used as inspiration for the design of new Islamic Art motifs that have local multi-cultural identity characteristics.
Abstrak
Usaha penerapan silang budaya tidak hanya tertumpu kepada aktiviti fizikal dalam masyarakat bahkan ia boleh diterapkan melalui pelbagai medium yang lain. Seni Islam masih mengekalkan cara persembahan yang sama dan tiada tranformasi baharu. Seni Islam adalah seni yang luas dan perlu berkembang serta diperkaya dengan kreativiti. Kajian ini akan mengenal pasti elemen seni silang budaya yang dapat menjana idea baharu bagi menghasilkan reka bentuk motif Seni Islam. Komponen silang budaya dalam kajian ini adalah berdasarkan konteks budaya tempatan yang terdiri daripada tiga major etnik di Malaysia. Kajian terhadap penghasilan motif yang berteraskan silang budaya amat kurang dalam konteks tempatan. Selain itu, tiada penambahan dan kreativiti baharu dalam bidang Seni Islam. Objektif kajian ini adalah untuk mengenal pasti elemen seni silang budaya yang boleh dijadikan inspirasi bagi menghasilkan reka bentuk motif, dan mencadangkan pembangunan reka bentuk motif Seni Islam berteraskan silang budaya. Pendekatan reka bentuk dan pembangunan yang didasari oleh model ADDIE digunakan dalam kajian ini. Elemen silang budaya seperti simbol, imej dan warna yang tidak bercanggah dengan teras kesenian Islam dapat manjana daya kreativiti yang tinggi dan mengilhamkan inovasi dalam menghasilkan motif Seni Islam. Penghasilan motif baharu Seni Islam ini juga berpotensi untuk diaplikasikan pada pelbagai platform. Kesimpulannya, elemen seni silang budaya berupaya dijadikan sebagai inspirasi bagi menghasilkan sebuah reka bentuk motif Seni Islam baharu yang mempunyai ciri-ciri identiti tempatan.
Prevalência de achados histopatológicos de mucosa esofágica e sua correlação com Helicobacter pylori
Authors: Souza Gabrielle Barbosa Vasconcelos de , Moura Elomar Rezende , Trindade Yasmin Tourinho Delmondes , Santana Neto Durval José de , Moreira Larissa Gonçalves , Carvalho Gabriel Ponciano Santos de , Barreto Íkaro Daniel de Carvalho , Silva Décio Fragata da , Meurer Luíse , Trindade Leda Maria Delmondes Freitas 
Published: January 2022

Introdução: patologias esofágicas com alterações histopatológicas podem provocar sintomas dispépticos, dor retroesternal e epigástrica. Objetivos: identificar a prevalência de achados histopatológicos de mucosa esofágica e correlacionar com a bactéria Helicobacter pylori (HP). Metodologia: estudo transversal, retrospectivo, com 1.953 laudos histopatológicos de mucosa esofágica. Dados analisados por frequência absoluta e relativa percentual, testes Qui-Quadrado de Pearson, Mann-Whitney e Teste Qui-Quadrado com simulações de Monte-Carlo. Resultados: Analisaram-se 1953 laudos de lesões esofágicas: sexo feminino 982 (50,3%) e idade mediana 44. Identificou-se 151 (7,7%) laudos positivos para HP e destes, 41 (2,3%) tinham atrofia gástrica. A esofagite 1427 (73,1%), a metaplasia 548 (28,1%) e o esôfago de Barrett 133 (6,8%) foram mais prevalentes. Malignidade, 5 (0,3%) laudos. Dos portadores de HP: esofagite 97 (64,2%), esôfago de Barrett 17 (11,3%) e metaplasia 45 (29,8%) - metaplasia pancreática estatisticamente significativa (p<0,001). Dois (1,3%) laudos apresentaram malignidade associados à HP. Correlacionando HP com lesões esofágicas, observou-se tendência a determinar maior risco da presença da bactéria: esôfago de Barret (RR: 1,68 (IC95%: 1,05-2,69), hiperplasia epitelial (RR: 2,18 (IC95%: 1,18-4,02), acantose glicogênica (RR: 3,69 (IC95%: 2,08-6,54), pólipos (RR: 2,17 (IC95%: 1,14-4,16), malignidade (RR: 4,91 (IC95%: 1,66-14,52) e atrofia gástrica (RR: 3,44 (IC95%: 2,02-5,84). Conclusão: Esôfago de Barrett, hiperplasia epitelial, acantose glicogênica, pólipos, malignidade e atrofia gástrica estão associados a um maior risco da presença da bactéria.
O atendimento interdisciplinar na Atenção Primária em Saúde - Revisão integrativa
Authors: Medeiros Patricia Cortez de , Melo Graziely Veríssimo de , Silva Artur Vinicius Lima e , Freitas Ruth Elisa de Lima , Moura Brunna Caroline Santos de , Costa Halanderson Cabral da , Silva Alyce Oliveira da , Coutinho Elton de Oliveira , Oliveira Jafia Andreza Gonçalves de , Andrade Carlos Henrique Souza , Silva Raylena de Andrade Catunda da , Santos Rianne Milenne de Lima Moares , Silva Rivaldo Alexsandro da , Azevedo Sheila Absalão 
Published: January 2022

O desempenho dos profissionais de saúde em equipes interdisciplinares na atenção primária em saúde do Sistema único de Saúde ganhou destaque no Brasil, principalmente durante a pandemia do COVID-19, época em que a saúde pública no país entrou em colapso, e que houve a necessidade de um maior número de profissionais atuando na área. Nesse sentido, o objetivo desse estudo foi avaliar o reflexo que a participação interdisciplinar possui na Atenção Primária (APS). Foram realizadas buscas nas bases de dados Scielo, Scopus, BVS, e no Google Acadêmico. Foram encontrados 285 artigos, dos quais, 44 apresentaram texto completo, sendo analisados seus resumos. Logo em seguida, 13 textos foram selecionados para análise. Observou-se que nos artigos investigados o trabalho em equipe tem contribuído efetivamente na evolução dos pacientes, e viabilizou a organização da atenção em saúde em uma perspectiva de práticas clínicas ampliadas centralizadas no indivíduo, na família e comunidade.
One-Step Generation and Purification of Cell-Encapsulated Hydrogel Microsphere With an Easily Assembled Microfluidic Device
Authors: Zhang Tao , Zhang Hong , Zhou Wuping , Jiang Keming , Liu Cong , Wang Ru , Zhou Yuanshuai , Zhang Zhiqiang , Mei Qian , Dong Wen-Fei , Sun Minxuan , Li Haiwen 
Published: January 2022

Cell-laden hydrogel microspheres with uniform size show great potential for tissue repair and drug screening applications. Droplet microfluidic systems have been widely used for the generation of cell-laden hydrogel microspheres. However, existing droplet microfluidic systems are mostly based on complex chips and are not compatible with well culture plates. Moreover, microspheres produced by droplet microfluidics need demulsification and purification from oil, which requires time and effort and may compromise cell viability. Herein, we present a simple one-step approach for producing and purifying hydrogel microspheres with an easily assembled microfluidic device. Droplets were generated and solidified in the device tubing. The obtained hydrogel microspheres were then transferred to a tissue culture plate filled with cell culture media and demulsified through evaporation of the oil at 37°C. The removal of oil caused the gelled microspheres to be released into the cell culture media. The encapsulated cells demonstrated good viability and grew into tumor spheroids in 12–14 days. Single cell-laden hydrogel microspheres were also obtained and grown into spheroid in 14 days. This one-step microsphere generation method shows good potential for applications in automated spheroid and organoid cultures as well as drug screening, and could potentially offer benefits for translation of cell/microgel technologies.
Dysregulation of the Intestinal Microbiome in Patients With Haploinsufficiency of A20
Authors: Toyofuku Etsushi , Takeshita Kozue , Ohnishi Hidenori , Kiridoshi Yuko , Masuoka Hiroaki , Kadowaki Tomonori , Nishikomori Ryuta , Nishimura Kenichi , Kobayashi Chie , Ebato Takasuke , Shigemura Tomonari , Inoue Yuzaburo , Suda Wataru , Hattori Masahira , Morio Tomohiro , Honda Kenya , Kanegane Hirokazu 
Published: January 2022

IntroductionHaploinsufficiency of A20 (HA20) is a form of inborn errors of immunity (IEI). IEIs are genetically occurring diseases, some of which cause intestinal dysbiosis. Due to the dysregulation of regulatory T cells (Tregs) observed in patients with HA20, gut dysbiosis was associated with Tregs in intestinal lamina propria.MethodsStool samples were obtained from 16 patients with HA20 and 15 of their family members. Infant samples and/or samples with recent antibiotics use were excluded; hence, 26 samples from 13 patients and 13 family members were analyzed. The 16S sequencing process was conducted to assess the microbial composition of samples. Combined with clinical information, the relationship between the microbiome and the disease activity was statistically analyzed.ResultsThe composition of gut microbiota in patients with HA20 was disturbed compared with that in healthy family members. Age, disease severity, and use of immunosuppressants corresponded to dysbiosis. However, other explanatory factors, such as abdominal symptoms and probiotic treatment, were not associated. The overall composition at the phylum level was stable, but some genera were significantly increased or decreased. Furthermore, among the seven operational taxonomic units (OTUs) that increased, two OTUs, Streptococcus mutans and Lactobacillus salivarius, considerably increased in patients with autoantibodies than those without autoantibodies.DiscussionDetailed interaction on intestinal epithelium remains unknown; the relationship between the disease and stool composition change helps us understand the mechanism of an immunological reaction to microorganisms.
Using Proteomic Approaches to Unravel the Response of Ctenocephalides felis felis to Blood Feeding and Infection With Bartonella henselae
Authors: André Marcos Rogério , Neupane Pradeep , Lappin Michael , Herrin Brian , Smith Vicki , Williams Taufika Islam , Collins Leonard , Bai Hongxia , Jorge Gabriel Lemes , Balbuena Tiago Santana , Bradley Julie , Maggi Ricardo G. , Breitschwerdt Edward B. 
Published: January 2022

Among the Ctenocephalides felis felis-borne pathogens, Bartonella henselae, the main aetiological agent of cat scratch disease (CSD), is of increasing comparative biomedical importance. Despite the importance of B. henselae as an emergent pathogen, prevention of the diseases caused by this agent in cats, dogs and humans mostly relies on the use of ectoparasiticides. A vaccine targeting both flea fitness and pathogen competence is an attractive choice requiring the identification of flea proteins/metabolites with a dual effect. Even though recent developments in vector and pathogen -omics have advanced the understanding of the genetic factors and molecular pathways involved at the tick-pathogen interface, leading to discovery of candidate protective antigens, only a few studies have focused on the interaction between fleas and flea-borne pathogens. Taking into account the period of time needed for B. henselae replication in flea digestive tract, the present study investigated flea-differentially abundant proteins (FDAP) in unfed fleas, fleas fed on uninfected cats, and fleas fed on B. henselae-infected cats at 24 hours and 9 days after the beginning of blood feeding. Proteomics approaches were designed and implemented to interrogate differentially expressed proteins, so as to gain a better understanding of proteomic changes associated with the initial B. henselae transmission period (24 hour timepoint) and a subsequent time point 9 days after blood ingestion and flea infection. As a result, serine proteases, ribosomal proteins, proteasome subunit α-type, juvenile hormone epoxide hydrolase 1, vitellogenin C, allantoinase, phosphoenolpyruvate carboxykinase, succinic semialdehyde dehydrogenase, glycinamide ribotide transformylase, secreted salivary acid phosphatase had high abundance in response of C. felis blood feeding and/or infection by B. henselae. In contrast, high abundance of serpin-1, arginine kinase, ribosomal proteins, peritrophin-like protein, and FS-H/FSI antigen family member 3 was strongly associated with unfed cat fleas. Findings from this study provide insights into proteomic response of cat fleas to B. henselae infected and uninfected blood meal, as well as C. felis response to invading B. henselae over an infection time course, thus helping understand the complex interactions between cat fleas and B. henselae at protein levels.
Applying Machine Learning to Carotid Sonographic Features for Recurrent Stroke in Patients With Acute Stroke
Authors: Lin Shih-Yi , Law Kin-Man , Yeh Yi-Chun , Wu Kuo-Chen , Lai Jhih-Han , Lin Chih-Hsueh , Hsu Wu-Huei , Lin Cheng-Chieh , Kao Chia-Hung 
Published: January 2022

BackgroundAlthough carotid sonographic features have been used as predictors of recurrent stroke, few large-scale studies have explored the use of machine learning analysis of carotid sonographic features for the prediction of recurrent stroke.MethodsWe retrospectively collected electronic medical records of enrolled patients from the data warehouse of China Medical University Hospital, a tertiary medical center in central Taiwan, from January 2012 to November 2018. We included patients who underwent a documented carotid ultrasound within 30 days of experiencing an acute first stroke during the study period. We classified these participants into two groups: those with non-recurrent stroke (those who has not been diagnosed with acute stroke again during the study period) and those with recurrent stoke (those who has been diagnosed with acute stroke during the study period). A total of 1,235 carotid sonographic parameters were analyzed. Data on the patients' demographic characteristics and comorbidities were also collected. Python 3.7 was used as the programming language, and the scikit-learn toolkit was used to complete the derivation and verification of the machine learning methods.ResultsIn total, 2,411 patients were enrolled in this study, of whom 1,896 and 515 had non-recurrent and recurrent stroke, respectively. After extraction, 43 features of carotid sonography (36 carotid sonographic parameters and seven transcranial color Doppler sonographic parameter) were analyzed. For predicting recurrent stroke, CatBoost achieved the highest area under the curve (0.844, CIs 95% 0.824–0.868), followed by the Light Gradient Boosting Machine (0.832, CIs 95% 0.813–0.851), random forest (0.819, CIs 95% 0.802–0.846), support-vector machine (0.759, CIs 95% 0.739–0.781), logistic regression (0.781, CIs 95% 0.764–0.800), and decision tree (0.735, CIs 95% 0.717–0.755) models.ConclusionWhen using the CatBoost model, the top three features for predicting recurrent stroke were determined to be the use of anticoagulation medications, the use of NSAID medications, and the resistive index of the left subclavian artery. The CatBoost model demonstrated efficiency and achieved optimal performance in the predictive classification of non-recurrent and recurrent stroke.
Characteristics of Infrared Radiation in the Failure of Phosphate Rock at Different Loading Rates
Authors: Gao Chengcheng , Lin Manqing , Lu Yongxiong , Zhang Dianji , Feng Guangliang , Liang Xiaoshuai 
Published: January 2022

Safe and effective mining of phosphate rock plays an important role in the sustainable development of phosphorus resources. The mechanical properties and failure process of phosphate rock under different mining rates remain unclear, further restricting the safe and efficient mining of phosphate rock. In this paper, infrared radiation and uniaxial compression tests of phosphate rock under different loading rates, e.g., 0.0005, 0.001, 0.005, and 0.01 mm/s, were conducted to investigate the failure process of phosphate rock. Energy evolution and infrared radiation characteristics of the phosphate rock damage process were analyzed using nondestructive, real-time, and noncontact infrared thermal imaging technology. The results show that the higher the loading rate of phosphate rock, the more obvious the high-temperature zone and high-temperature point of phosphate rock in the loading process. At failure, the friction and slippage between internal cracks are intense, showing that the infrared radiation temperature difference increases with the increase of loading rate. As loading rate increases, the energy release time of phosphate rock before damage is reduced, resulting in more energy stored in the rock as evinced by its infrared radiation characteristics, finally resulting in greater damage. The increase of loading rate reduces the dissipation energy of phosphate rock before failure so that more energy remains in the rock mass through the weak surface of the grain boundary. The results of this work will be helpful in enhancing theoretical support for prevention and control of dynamic disasters in phosphate mines.