bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamical Controls of the Eastward Transport of Overwintering Calanus finmarchicus From the Lofoten Basin to the Continental Slope
Authors: Dong Huizi , Zhou Meng , Smith Walker O. , Li Baosheng , Hu Ziyuan , Basedow Sünnje L. , Gaardsted Frank , Zhang Zhaoru , Zhong Yisen 
Published: September 2022

AbstractDiapausing populations of Calanus finmarchicus at depth in the Lofoten Basin (LB) return to the continental shelf and slope off the Lofoten‐Vesterålen Islands during the phytoplankton spring bloom to feed and spawn, forming surface swarms with a great abundance. To study how overwintering populations of C. finmarchicus move with the deep currents and return to the shelf, Lagrangian transport characteristics of particles in deep water between 2008 and 2019 were analyzed using Global Ocean Reanalysis and Simulation re‐analysis data and Lagrangian Coherent Structures (LCSs). Our analyses revealed that persistent eastward transport of diapausing C. finmarchicus between LB and continental slope occurred mainly between 600 and 1,100 m in the Arctic Intermediate Water. The consistency of the vertical distributions of C. finmarchicus abundance and salinity further suggests that physical factors control the horizontal distribution of the species. Hovmöller diagrams of kinetic energy indicate that there is an eastward advection of mean current at depth. The co‐occurrence between the eastward transport of LCSs and the eastward advection of the mean current provides direct evidence that the life history of C. finmarchicus is subjected to physical control in the Norwegian Sea.
HCCANet: histopathological image grading of colorectal cancer using CNN based on multichannel fusion attention mechanism
Authors: Zhou Panyun , Cao Yanzhen , Li Min , Ma Yuhua , Chen Chen , Gan Xiaojing , Wu Jianying , Lv Xiaoyi , Chen Cheng 
Published: September 2022

AbstractHistopathological image analysis is the gold standard for pathologists to grade colorectal cancers of different differentiation types. However, the diagnosis by pathologists is highly subjective and prone to misdiagnosis. In this study, we constructed a new attention mechanism named MCCBAM based on channel attention mechanism and spatial attention mechanism, and developed a computer-aided diagnosis (CAD) method based on CNN and MCCBAM, called HCCANet. In this study, 630 histopathology images processed with Gaussian filtering denoising were included and gradient-weighted class activation map (Grad-CAM) was used to visualize regions of interest in HCCANet to improve its interpretability. The experimental results show that the proposed HCCANet model outperforms four advanced deep learning (ResNet50, MobileNetV2, Xception, and DenseNet121) and four classical machine learning (KNN, NB, RF, and SVM) techniques, achieved 90.2%, 85%, and 86.7% classification accuracy for colorectal cancers with high, medium, and low differentiation levels, respectively, with an overall accuracy of 87.3% and an average AUC value of 0.9.In addition, the MCCBAM constructed in this study outperforms several commonly used attention mechanisms SAM, SENet, SKNet, Non_Local, CBAM, and BAM on the backbone network. In conclusion, the HCCANet model proposed in this study is feasible for postoperative adjuvant diagnosis and grading of colorectal cancer.
Online review analysis on various networks’ consumer feedback using deep learning
Authors: Liu Huajin 
Published: September 2022

AbstractIn order to understand the application of deep learning in consumer online review analysis, the text content of online review and the impact of national culture on it are studied. A consumer online comment analysis model based on deep learning is constructed and utilised using edge computing. With the online reviews of mobile phone and computer products as the case, the analysis is made. The data of online reviews on various network platforms is obtained. The model based on edge computing is used for analysis, and the results of product feature sentiment analysis are obtained. The results show that the deep learning model can achieve effective product feature extraction and high accuracy sentiment analysis, which is reasonable and effective in practical application.
Multi‐stage flexible planning of regional electricity‐HCNG‐integrated energy system considering gas pipeline retrofit and expansion
Authors: Qiu Yue , Zhou Suyang , Gu Wei , Ding Shixing , Han Gaoyan , Zhang Kang , Lv Hongkun 
Published: September 2022

AbstractThe development of hydrogen‐enriched compressed natural gas (HCNG) can make full use of the existing natural gas infrastructure, thereby alleviating the economic and technical pressure on the development of pure hydrogen. This paper proposes a multi‐stage flexible planning method for the regional electricity‐HCNG‐integrated energy system (E‐HCNG‐IES), which considers the medium and long‐term dynamic characteristics of the E‐HCNG‐IES. For each sub‐regional energy station, an energy‐hub type model including hydrogen/HCNG‐related equipment and facilities is established. Considering the influence of hydrogen blending on the energy delivery capacity and line pack of pipelines, a hydrogen‐resistant retrofit model for existing natural gas pipelines between sub‐regions is proposed. Meanwhile, the model for newly constructed hydrogen pipelines is also presented. Subsequently, a series of flexibility evaluation indicators are proposed to support the performance analysis of planning schemes. The lateral comparison of sub‐cases in Changzhou, China demonstrates that considering the hydrogen‐resistant retrofit of natural gas pipelines can reduce the construction cost of hydrogen pipelines by about 37.12%. The peak shaving capacity of underground hydrogen storage (UHS), the energy recycling ability of turbo expander (TE), and the space‐time decoupling ability of hydrogen in energy supply and demand have also been confirmed.
GRB 080928 afterglow imaging and spectro-polarimetry
Authors: Brivio R. , Covino S. , D’Avanzo P. , Wiersema K. , Maund J. R. , Bernardini M. G. , Campana S. , Melandri A. 
Published: September 2022

Context. Among the large variety of astrophysical sources that we can observe, gamma-ray bursts (GRBs) are the most energetic of the whole Universe. Their emission peaks in the γ-ray band, with a duration from a fraction of a second to a few hundred seconds, and is followed by an afterglow covering the whole electromagnetic spectrum. The definition of a general picture describing the physics behind GRBs has always been a compelling task, but the results obtained so far from observations have revealed a puzzling landscape. The lack of a clear, unique paradigm calls for further observations and additional, independent techniques for this purpose. Polarimetry constitutes a very useful example as it allows us to investigate some features of the source such as the geometry of the emitting region and the magnetic field configuration.
Aims. To date, only a handful of bursts detected by space telescopes have been accompanied by ground-based spectro-polarimetric follow-up, and therefore such an analysis of more GRBs is of crucial importance in order to increase the sample of bursts with multi-epoch polarisation analysis. In this work, we present the analysis of the GRB 080928 optical afterglow, with observations performed with the ESO-VLT FORS1 instrument.
Methods. Starting from raw data taken in the imaging polarimetry (IPOL) and spectro-polarimetry (PMOS) modes, we performed data reduction, followed by the photometric analysis of IPOL data, taken ~14 and ~40 h after the burst detection, and spectroscopy of PMOS data (t ~ 14.95 h). After computing the reduced Stokes parameters Q/I and U/I, which describe the linear polarisation of the emitted radiation, we obtained the polarisation degree for the three observing epochs.
Results. We find that the GRB optical afterglow was not significantly polarised on the first observing night. The polarisation degree (P) grew on the following night to a level of P ~ 4.5%, giving evidence of polarised radiation at a 4σ confidence level. The GRB 080928 light curve is not fully consistent with standard afterglow models, making any comparison with polarimetric models partly inconclusive. The most conservative interpretation is that the GRB emission was characterised by a homogeneous jet and was observed at an angle of 0.6 <θobs/θjet < 0.8. Moreover, the non-zero polarisation degree on the second night suggests the presence of a dominant locally ordered magnetic field in the emitting region.
Trypsin-Inhibitor-Aktivität im Kolostrum – eine Übersicht
Authors: Georgiev Plamen , Wehrend Axel , Trzebiatowski Lukas 
Published: September 2022

ZusammenfassungDie wichtige Rolle von Kolostrum für das Immunsystem des Neonaten ist lange bekannt. Proteine und vor allem Immunglobuline müssen nach der Aufnahme den Verdauungstrakt mit seinen proteolytischen Enzymen intakt passieren, um in den neonatalen Kreislauf aufgenommen werden zu können. Aus diesem Grund weist Kolostrum eine trypsininhibitorische Aktivität auf. Die Anti-Trypsin-Aktivität wird dabei nicht nur von einem einzigen Molekül getragen, sondern ist eine generelle Eigenschaft des Erstkolostrums. Bei Paarhufern lässt sich eine hohe Trypsin-Inhibition nachweisen, die in den ersten Tagen der Laktation stark abfällt. Auch beim Pferd ist eine Trypsin-Inhibition im Kolostrum festzustellen. Die Bedeutung wird in der Literatur kontrovers diskutiert, weil die Anti-Trypsin-Aktivität im Vergleich zu den Klauentieren geringer ausgeprägt ist und weniger Stabilität im sauren Milieu zeigt. Im Kolostrum von Fleischfressern findet sich ebenfalls eine Anti-Trypsin-Aktivität, die jedoch weniger stark ausgeprägt ist als bei den Huftieren. Diese Literaturübersicht hat zum Ziel, das bekannte Wissen zur Anti-Trypsin-Aktivität im Kolostrum verschiedener Spezies zusammenzufassen.
Glaukomassoziierte Makulopathien
Authors: Teuchner Barbara , Rauchegger Teresa 
Published: September 2022

ZusammenfassungBei Vorliegen eines Glaukoms kann es im Verlauf der Erkrankung selbst oder von dessen Therapie zu verschiedenen Veränderungen in der Makula kommen. Zu den Makulopathien, die bei Glaukomen
beobachtet werden können, zählen das zystoide Makulaödem, die hypotone Makulopathie und das mikrozystische Makulaödem. Im folgenden Artikel wird auf Pathophysiologie, Ursachen, Verlauf,
klinisches Erscheinungsbild und Therapie dieser Makulopathien eingegangen.
Hörverlust nach Anwendung topischer Otitispräparate bei Hunden
Authors: Neubert Ann , Tannert Sabine , Pirk Gwenda 
Published: September 2022

ZusammenfassungGegenstand und Ziel Über Hörverlust, der in zeitlichem Zusammenhang mit der topischen Anwendung von Otologika auftritt, wird dem Bundesamt für Verbraucherschutz und Lebensmittelsicherheit (BVL) regelmäßig in Form von Meldungen unerwünschter Arzneimittelwirkungen (UAW) berichtet. Obwohl in den Fachinformationen der in Deutschland zugelassenen Otologika Taubheit oder Beeinträchtigung des Hörvermögens als mögliche Nebenwirkungen aufgeführt sind, gibt es über die zugrundeliegenden Ursachen nur wenig Informationen.Material und Methoden Fälle zu Hörverlust nach Anwendung von Otologika wurden in der nationalen UAW-Datenbank des BVL recherchiert und deskriptiv analysiert. Dabei wurden Fälle,in denen Katzen betroffen waren, aufgrund der geringen Anzahl ausgeschlossen. Mögliche Risikofaktoren und Ursachen für Hörverlust wurden vor dem Hintergrund aktueller Literatur betrachtet.Ergebnisse Obwohl in den Berichten Tiere aller Altersgruppen betroffen waren, bezog sich der überwiegende Anteil der Meldungen auf Tiere, die älter als 10 Jahre waren. Nach Mischlingen waren am häufigsten Hunde der Rassen West Highland White Terrier, Dalmatiner, Zwergpudel und Französische Bulldogge involviert. Die Analyse der vorliegenden Daten deutet nicht auf spezifische Präparate oder Wirkstoffe hin, welche mit gehäuftem Auftreten eines Hörverlusts in Verbindung stehen könnten.Schlussfolgerung und klinische Relevanz Neben einer möglichen Ototoxizität eines Präparates sollten auch andere Ursachen für den Hörverlust in Betracht gezogen werden, wie z. B. die zugrundeliegende Otitis selbst, Altersschwerhörigkeit, eine bisher unentdeckte einseitige Taubheit oder Schallleitungstaubheit durch Obstruktion des Gehörgangs. Neben dem Absetzen potenziell ototoxischer Stoffe kommt die Behandlung von Schallleitungstaubheit, z. B. durch die Entfernung von Medikamentenresten und Exsudat oder die Behandlung einer Otitis media, als Therapieoption infrage. Im Fall eines Hörverlusts nach der Anwendung von Otologika sollte eine möglichst detaillierte Meldung dieses Ereignisses an das BVL erfolgen, um die Datenlage zu diesem Thema weiter zu verbessern.
Prevalence and clinical relevance of udder thigh dermatitis in dairy cows
Authors: Avenarius Andreas , Wehrend Axel , Sickinger Marlene 
Published: September 2022

AbstractObjective Udder thigh dermatitis (UTD) is especially common in heifers. Skin alterations and necrosis of muscle tissue characterise this condition and, although the disease is well understood, systematic analysis concerning prevalence, risk factors and consequences of UTD is lacking. The aim of this study, therefore were such systematic clinical examinations.Material and methods Statistical analyses of data were performed to objectively evaluate the supposed higher risk of heifers developing UTD. The study included a total of 317 animals that were examined and classified as UTD positive or negative on the day of calving. The size of skin alterations and the severity of tissue damage were assessed on days 7, 14 and 21 p. p.Results The overall prevalence resulted in 18 % UTD with a higher risk in heifers (36.8 %) than in cows (4.3 %; P < 0.0001). A significant link was found between the size of tissue lesions and severity of UTD (day 7: P = 0.007; day 14: P = 0.002; day 21: P = 0.011). Peripartal udder oedemas were strongly associated with UTD (P < 0.05). The milk yield and the concentration of milk protein was found to have decreased.Conclusion UTD appears to be a multi-factorial disease that is supposed to be painful due to the obvious avoidant behaviour in affected animals. In respect to the reduction in daily milk yield and an enhancement of pain related stress, neither the economic impact of UTD, nor the adverse effects on animal welfare should be underestimated.Clinical relevance Heifers with udder oedema are advised to be examined for the presence of UTD in order to start an early treatment and diminish disease related negative impacts.
Pigeon Rotavirus A as the cause of systemic infection in juvenile pigeons (young pigeon disease)
Authors: Meßmer Christian , Rubbenstroth Dennis , Mohr Lydia , Peus Elisabeth , Schreiber Tim , Rautenschlein Silke 
Published: September 2022

AbstractRecent investigations suggested pigeon associated Rotavirus Typ A genotype G18P[17] (RVA) as a causative agent of the classical ‘young pigeon disease’ (YPD). YPD was first described in the late 1980 s as an acute, mainly seasonally recurring disorder of mostly juvenile domestic pigeons (Columba livia) with clinical signs such as anorexia, dairrhea, vomiting, congested crops, weight loss and occasionally mortality. Various studies in the past indicated a multifactorial nature of YPD. Several pathogens, such as pigeon circovirus 1, avian adenoviruses and Escherichia coli were also suggested, but none of these could reproduce the disease experimentally. However, the impact of other pathogens on the clinical development of YPD cannot be excluded and requires further investigation. This present review summarizes available information on RVA-induced disease in pigeons, its association with YPD, the transmission, and diagnosis of the infection, and on prophylactic strategies to prevent RVA outbreaks.
Placenta Accreta Spectrum Prenatal Diagnosis Performance: Are Ultrasound False-positive Results Acceptable in Limited-resources Settings?
Authors: Nieto-Calvache Albaro José , Benavides-Calvache Juan Pablo , Hidalgo Alejandra , Padilla Natalia , López-Tenorio Jaime , Victoria Alejandro , Rengifo Martin , Mejía Mauricio , Vergara-Galliadi Lina María , Sinisterra-Díaz Stiven Ernesto , Maya Juliana , Zambrano María Andrea , Burgos-Luna Juan Manuel 
Published: September 2022

Abstract
Objective The immediate referral of patients with risk factors for placenta accreta spectrum (PAS) to specialized centers is recommended, thus favoring an early diagnosis and an interdisciplinary management. However, diagnostic errors are frequent, even in referral centers (RCs). We sought to evaluate the performance of the prenatal diagnosis for PAS in a Latin American hospital.
Methods A retrospective descriptive study including patients referred due to the suspicion of PAS was conducted. Data from the prenatal imaging studies were compared with the final diagnoses (intraoperative and/or histological).
Results A total of 162 patients were included in the present study. The median gestational age at the time of the first PAS suspicious ultrasound was 29 weeks, but patients arrived at the PAS RC at 34 weeks. The frequency of false-positive results at referring hospitals was 68.5%. Sixty-nine patients underwent surgery based on the suspicion of PAS at 35 weeks, and there was a 28.9% false-positive rate at the RC. In 93 patients, the diagnosis of PAS was ruled out at the RC, with a 2.1% false-negative frequency.
Conclusion The prenatal diagnosis of PAS is better at the RC. However, even in these centers, false-positive results are common; therefore, the intraoperative confirmation of the diagnosis of PAS is essential.
Total ionization dose radiation tests results of the epoch timing system with sub-picosecond resolution and stability for its applications in space missions
Authors: Prochazka Ivan , Blazej Josef , Kodet Jan 
Published: September 2022

We report on the concept, design, and tests of a New Picosecond Event Timer (NPET) device and its response to the total ionizing dose. These radiation tests aimed to verify that the existing version of the NPET device may be used in space missions. The device was subjected to radiation of a total dose of 74 Gy provided by a 60Co source. The epoch timing part of the device was not detectably affected by the radiation dose. After the radiation dose, the epoch timing of single measurement resolution is better than 0.9 ps with the overall timing stability characterized by Time Deviation being better than 5 fs for averaging times of 100 s. The completed device tests and results indicate the possibility of using the existing version of the New Pico Event Timing device electronics for a space mission in which the total radiation dose will not exceed 74 Gy value.
Silicon-mediated improvement of biomass yield and physio-biochemical attributes in heat-stressed spinach (
Authors: Khosa Quratulain , Zaman Qamar uz , An Tingting , Ashraf Kamran , Abbasi Asim , Nazir Saba , Naz Riffat , Chen Yinglong 
Published: September 2022

Context Defensive action of plants against biotic and abiotic stresses has been augmented by silicon (Si). Spinach (Spinacia oleracea L.) is a nutritious leafy vegetable that is a cold-tolerant but heat-sensitive crop. Aims and methods The ability of exogenous application of Si (0, 2, 4 and 6 mmol L−1 in the form of K2SiO3) to alleviate heat stress in spinach cv. Desi Palak was investigated. After an acclimatisation period, plants were grown with or without heat stress for 15 days, followed by Si treatment for 25 days. Plant growth and physiology were assessed at 65 days after sowing. Key results Heat stress significantly inhibited plant growth, water status and photosynthesis, soluble sugar and protein contents, and osmolyte status in spinach leaves, but increased electrolyte leakage, activities of antioxidant enzymes, and proline content. Application of Si alleviated heat stress by enhancing water status, photosynthetic pigments, soluble proteins and essential minerals, and by reducing damage of the plasma membrane. The accumulation of osmolytes counterbalance the osmotic stress imposed by heat. Conclusions Silicon plays a vital role in alleviating effects of heat stress by improving water status and photosynthetic rate, and accruing osmoprotectants other than proline. Implications Exogenous application of Si is an efficient strategy to boost tolerance of spinach plants to heat stress, having significant impact on growth and productivity of spinach at higher temperatures.
KidA, a multi-PAS domain protein, tunes the period of the cyanobacterial circadian oscillator
Authors: Kim Soo Ji , Chi Chris , Pattanayak Gopal , Dinner Aaron R. , Rust Michael J. 
Published: September 2022

The cyanobacterial clock presents a unique opportunity to understand the biochemical basis of circadian rhythms. The core oscillator, composed of the KaiA, KaiB, and KaiC proteins, has been extensively studied, but a complete picture of its connection to the physiology of the cell is lacking. To identify previously unknown components of the clock, we used KaiB locked in its active fold as bait in an immunoprecipitation/mass spectrometry approach. We found that the most abundant interactor, other than KaiC, was a putative diguanylate cyclase protein predicted to contain multiple Per-Arnt-Sim (PAS) domains, which we propose to name KidA. Here we show that KidA directly binds to the fold-switched active form of KaiB through its N-terminal PAS domains. We found that KidA shortens the period of the circadian clock both in vivo and in vitro and alters the ability of the clock to entrain to light-dark cycles. The dose-dependent effect of KidA on the clock period could be quantitatively recapitulated by a mathematical model in which KidA stabilizes the fold-switched form of KaiB, favoring rebinding to KaiC. Put together, our results show that the period and amplitude of the clock can be modulated by regulating the access of KaiB to the fold-switched form.
A corpus-based study of anglicized neologisms in Korea
Authors: Kim Eun-Young Julia 
Published: September 2022

Abstract
This study examines usage changes of English-based loanwords and Korean replacement words promoted by the National
Institute of Korean Language in a six-year span, using two corpora. It focuses on 18 Korean and anglicized word pairs appearing on
the National Institute of Korean Language’s website that purportedly showcase the Institute’s successful efforts to curtail the
usage of English words by promoting Korean replacement words. The results indicate that promoting Korean does not necessarily
decrease the usage of English, and that the usage of English-based words seems to increase in conjunction with the Korean words.
Several Korean words promoted by the National Institute of Korean Language have extremely low frequencies, and some loanwords are
being used with various meanings. Commentaries are provided to explain various patterns of observed usage change.