bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis and characterization of stir casted Cu-ZrO2-Graphite hybrid metal matrix composites for thermal management structures
Authors: Mittal Prateek , Acharya Vishwas , Kumar Sanjeet , Paswan Manikant , Sadasivuni Kishor Kumar , Gupta Pallav 
Published: April 2022

The present study aims at investigating the properties of copper matrix-based hybrid metal matrix composites (MMCs) reinforced with ZrO2 and Graphite. The MMCs were prepared using stir casting technique. The composite material was developed for its application in thermal management structures. The properties of the prepared MMCs were found to be dependent on the reinforcements content present in the MMCs. ZrO2 and Graphite reinforcements were added (0.5–0.5, 1.0–1.0, 1.5–1.5 and 2.0–2.0 wt %) in the four composite samples prepared via stir casting. Amongst several available techniques, stir casting was chosen to prepare the samples due to its simplicity and economic viability. The phase identification was done by using X-ray diffraction (XRD) and the microstructure was observed using Scanning Electron Microscopy (SEM). No intermediate phase was observed from the XRD results. The reinforcement phase was found to be dispersed in a uniform manner as observed through the SEM micrographs. The density of the samples was found to decrease with an increase in the reinforcements content. The density of the composite sample containing 2 wt. % of each reinforcement was found to be 8.01 g/cm3 which was 10% lesser than pure copper. Hardness of pure copper sample was found to be 35.71 BHN; however, the hardness of composite sample containing 4 wt. % of each of the reinforcements was found to be 70.14 BHN which indicates an increase of around 100%. Wear rate of pure copper and composite sample containing 5 wt. % of each of the reinforcements was found to be 0.3788 mm3/Km and 0.3603 mm3/Km, respectively, at 20 N load. However, the composite samples consisting of 4 wt. % of each of the reinforcements exhibited wear rate of 0.3001 mm3/Km which was 20% lesser than that of pure copper at the same load. The compressive strength of composite sample containing 2.0 wt. % ZrO2 and graphite was found to be 674.57 MPa which was around 1.25% higher than the composite sample containing 0.5 wt. % reinforcements. The specific heat of the samples was found to increase marginally with an increase in reinforcement content. It is expected that the hybrid composites developed will be suitable for use in structural applications pertaining to thermal management.
‘Zonked the hell out’: Climate change and heat stress at work
Authors: Humphrys Elizabeth , Goodman James , Newman Freya 
Published: April 2022

AbstractClimate change is most directly felt by people who cannot escape its impacts, including workers whose source of livelihood may put them directly at risk from high heat. Research on these impacts for Australian workers, especially the sociopolitical determinants of effective workplace heat management, remains limited. This article presents findings from a national research project that investigated these issues in collaboration with the Australia-based United Workers Union. It reports on the experiences of members exposed to high heat, explores how they address heat stress and how they relate this to climate change. The article expands understanding of the impacts of workplace heat, especially for indoor workers and those in lower paid jobs, through a focus on how workers articulate their experiences and understand and exercise their agency at work.
Development and Validation of Machine Learning Models to Predict Epidermal Growth Factor Receptor Mutation in Non-Small Cell Lung Cancer: A Multi-Center Retrospective Radiomics Study
Authors: Liu Yafeng , Zhou Jiawei , Wu Jing , Wang Wenyang , Wang Xueqin , Guo Jianqiang , Wang Qingsen , Zhang Xin , Li Danting , Xie Jun , Ding Xuansheng , Xing Yingru , Hu Dong 
Published: April 2022

Objective To develop and validate a generalized prediction model that can classify epidermal growth factor receptor (EGFR) mutation status in non–small cell lung cancer patients. Methods A total of 346 patients (296 in the training cohort and 50 in the validation cohort) from four centers were included in this retrospective study. First, 1085 features were extracted using IBEX from the computed tomography images. The features were screened using the intraclass correlation coefficient, hypothesis tests and least absolute shrinkage and selection operator. Logistic regression (LR), decision tree (DT), random forest (RF), and support vector machine (SVM) were used to build a radiomics model for classification. The models were evaluated using the following metrics: area under the curve (AUC), calibration curve (CAL), decision curve analysis (DCA), concordance index (C-index), and Brier score. Results Sixteen features were selected, and models were built using LR, DT, RF, and SVM. In the training cohort, the AUCs was .723, .842, .995, and .883; In the validation cohort, the AUCs were .658, 0567, .88, and .765. RF model with the best AUC, its CAL, C-index (training cohort=.998; validation cohort=.883), and Brier score (training cohort=.007; validation cohort=0.137) showed a satisfactory predictive accuracy; DCA indicated that the RF model has better clinical application value. Conclusion Machine learning models based on computed tomography images can be used to evaluate EGFR status in patients with non–small cell lung cancer, and the RF model outperformed LR, DT, and SVM.
Improved low-frequency sound absorption of porous silicone rubber resonance sheet with periodic cavities
Authors: Peng Longgui , Zhao Pu , Cheng Huanquan , He Qirui , Du Lifei 
Published: April 2022

Since the development of advanced sound absorption material is highly critical in noise control applications, anechoic coatings, and acoustic metamaterials, both fabrication technology and structure design are significant in the achievement of broadband and strong absorption performance in the low sound frequency range. In this work, the silicone rubber resonance absorption sheet with periodic cavities is prepared via inserting cylindrical steel strips with different diameters into the non-vulcanized colloid. Effects of size and arrangement of cavities on the sound absorption properties, as well as the corresponding mechanical properties, are investigated and discussed. Results indicate that periodic pattern designs could further improve the low-frequency sound absorption performance of silicone rubber foams, and increasing the cavity diameter could significantly improve the sound absorption efficiency of the prepared samples in the middle- and low-frequency range from 125 to 2000 Hz. Particularly, increasing the number of the layered cavities could also improve the sound absorption efficiency. The consumption of sound energy in the prepared silicone rubber resonance sheet is discussed, which could be attributed to the synergistic effect in different spatial scales.
Long-term Outcomes of the Endurant and Excluder Stent Grafts for Endovascular Aneurysm Repair in a Japanese Cohort
Authors: Sekimoto Yasuhito , Fujimura Naoki , Matsubara Kentaro , Uchida Norio , Asami Atsunori , Harada Hirohisa , Shintani Tsunehiro , Watada Susumu , Ono Shigeshi , Fujii Taku , Shimogawara Tatsuya , Hayashi Keita , Hayashi Masanori , Obara Hideaki , Kitagawa Yuko 
Published: April 2022

Purpose: To compare the long-term outcomes of the most widely used third-generation stent grafts, the Endurant and Excluder stent grafts, in Japanese patients using a multicenter registry. Materials and Methods: A retrospective analysis of endovascular aneurysm repairs for abdominal aortic and iliac artery aneurysms using either the Endurant or the Excluder stent grafts from January 2012 to July 2019 at 10 Japanese hospitals was performed. Results: A total of 332 and 378 repairs using the Endurant and Excluder stent grafts, respectively, were analyzed. Although the patients’ characteristics were generally similar in the two groups, the Endurant group exhibited significantly shorter (Endurant: 31.5±18.6 mm, Excluder: 37.4±21.0 mm; p<0.001), larger (Endurant: 22.4±4.2 mm, Excluder: 21.7±3.8 mm; p=0.029), and more reversed tapered (Endurant: 12.1%, Excluder: 5.8%; p=0.003) proximal necks. The incidence of instructions for use (IFU) violations was similar between the two groups (Endurant: 59.0%, Excluder: 54.5%; p=0.223). However, the Endurant group had significantly more proximal neck-related IFU violations (54.1% and 46.3%, respectively; p=0.039), more access-related IFU violations (8.1% and 4.0%, respectively; p=0.019), and fewer bilateral hypogastric artery embolizations (5.1% and 9.3%, respectively; p=0.035) compared with the Excluder group. The incidence of intraoperative (Endurant: 3.6%, Excluder: 3.7%; p=0.950) and perioperative complications (Endurant: 3.6%, Excluder: 3.4%, p=0.899) was equivalent in the two groups. However, there was a significantly higher incidence of postoperative type II endoleaks in the Excluder group (Endurant: 28%, Excluder: 46.0%, p<0.001). Aneurysm sac regression was more frequent in the Endurant group (Endurant: 40.7%, Excluder: 31.7%, p=0.013). The Endurant group also had significantly higher rates of sac increase (Endurant: 13.0%, Excluder: 7.7%, p=0.020). Kaplan-Meier curve and log-rank analyses revealed no statistical differences in late complications (p=0.868) and overall survival (p=0.926). Conclusions: There were no statistically significant differences between the Endurant and the Excluder stent grafts in terms of intraoperative, perioperative, and late complication rates; however, the anatomical characteristics of the patients were significantly different.
Salvage of an Incomplete Sandwich With a Covered Celiac Trunk and a “Floating” Superior Mesenteric Artery Stent in a Thoracoabdominal Aortic Aneurysm
Authors: Gouveia e Melo Ryan , Ginthoer Benedict , Fernández Prendes Carlota , Stana Jan , Stavroulakis Konstantinos , Rantner Barbara , Tsilimparis Nikolaos 
Published: April 2022

Purpose: To report a case of a patient with a large thoracoabdominal aortic aneurysm (TAAA) extent V treated with a custom-made fenestrated and branched endovascular repair (F/B-EVAR) after a failed and incomplete attempt of a Sandwich repair technique. Report: An 83-year-old patient was referred to our department after a failed attempt at endovascular repair of type V TAAA with a sandwich technique. The celiac trunk was inadvertently covered with the first endograft and a covered long superior mesenteric artery stent was placed and left facing upward inside the aorta. We performed a staged repair, by first catheterizing and stenting the celiac trunk and bringing it under and inside the main aortic endograft. In interval, a F/B-EVAR was performed using a bimodular custom-made device (CMD) with a proximal 2 branch module for the celiac trunk and superior mesenteric artery and distal module with fenestrations for both renal arteries. The intervention was successful, and the follow-up was uneventful at 6 months. Conclusions: Re-intervention after failed endovascular attempts of TAAA repair are technically challenging and require advanced endovascular techniques. The ability to construct CMDs allowed to extend repair to our patient which had severe anatomical constraints for other techniques.
Towards a patient-centred approach in therapeutic patient education. A qualitative study exploring health care professionals’ practices and related representations
Authors: Roussel Sandrine , Frenay Mariane 
Published: April 2022

Objectives This study aimed to explore the practice-representation links among Health Care Professionals (HCP)s practising Therapeutic Patient Education (TPE). Understanding these links might actually help to address the challenges of TPE implementation, particularly the patient-centred dimension. Methods A qualitative study using individual interviews was conducted with HCPs practising in French-speaking Belgium or in France. Data analysis was carried out in two steps: to draw up a typology of educational practices (including variations) and, in line with the Social Representation Theory, to identify possible related social representations. Results The typology, based on HCP-Patient power distribution, was built from 26 interviews. Four types and nine subtypes were identified. Besides the power distribution, practice (sub)types were also specific regarding communication modes, consideration for patients’ representations, motivational approach, personalization, complexity of methods and learning contents, and practice reflexivity. Practices were seldom constant. Three variations were highlighted: within a subtype, between different subtypes, and between education and technical care. Both practice subtypes and variations were related to specific decisive representations. Discussion Representations related to practices and those related to practices variations offer new perspectives for TPE implementation. There is no panacea for achieving more patient-centred approaches; tailored strategies based on practice subtypes are needed.
Glycemic Outcomes During Real-World Hybrid Closed-Loop System Use by Individuals With Type 1 Diabetes in the United States
Authors: Arunachalum Siddharth , Velado Kevin , Vigersky Robert A. , Cordero Toni L. 
Published: April 2022

Background: Glycemic outcomes during real-world hybrid closed-loop (HCL) system use by individuals with type 1 diabetes, in the United States, were retrospectively analyzed. Methods: Hybrid closed-loop system data voluntarily uploaded to Carelink™ personal software from March 2017 to November 2020 by individuals (aged ≥7 years) using the MiniMed™ 670G system and having ≥10 days of continuous glucose monitoring data after initiating Auto Mode were assessed. Glycemic outcomes including the mean glucose management indicator (GMI), sensor glucose (SG), percentage of time spent in (TIR), below (TBR), and above (TAR) target range (70-180 mg/dL) were analyzed. Outcomes were also analyzed in a subgroup of users per baseline GMI of <7% versus >8%. Results: The overall cohort (N = 123 355 users, with a mean of 87.9% of time in Auto Mode) had a GMI of 7.0% ± 0.4%, TIR of 70.4% ± 11.2%, TBR <70 mg/dL of 2.2% ± 2.1% and TAR>180 mg/dL of 27.5% ± 11.6%, post-Auto Mode initiation. Compared with pre-Auto Mode initiation, users (N = 52 941, 88.6% of time in Auto Mode) had a GMI that decreased from 7.3% ± 0.6% to 7.1% ± 0.5% ( P < .001), TIR that increased from 61.5% ± 15.1% to 68.1% ± 11.9% ( P < .001), TAR>180 mg/dL that decreased from 36.3% ± 15.7% to 29.8% ± 12.2% ( P < .001) and TBR<70 mg/dL that decreased from 2.11 ± 2.4 to 2.07% ± 2.25% ( P = .002). While all metrics statistically improved for the baseline GMI >8.0% group, the baseline GMI <7.0% group had unchanged TIR (77.4% ± 7.4% to 77.5% ± 8.0%, P = .456) and TAR>180 mg/dL that increased (19.2 ± 6.7 to 19.6 ± 7.9%, p < 0.001). Conclusion: Real-world HCL system use in the U.S. demonstrated overall glycemic control that trended similarly with the system pivotal trial outcomes and previous real-world system use analyses.
Is eNAMPT/visfatin a potential serum marker of papillary thyroid cancer?
Authors: Sawicka-Gutaj Nadia , Ziółkowska Paulina , Derwich Aleksandra , Gut Paweł , Czarnywojtek Agata , Kloska Michał , Ruchała Marek 
Published: April 2022

Purpose: The role of nicotinamide phosphoribosyltransferase (NAMPT)/visfatin in a more aggressive course of many malignancies has been proven. Previous studies have noticed the importance of visfatin in thyroid neoplastic tissue, but the diagnostic and prognostic value of its serum concentration has not been investigated so far. Our study aimed to consider whether extracellular NAMPT (eNAMPT) could be a potential serum marker in recurrent papillary thyroid cancer (PTC). Methods: It was a prospective observational study with consecutive enrolment. We recruited 100 patients with PTC after thyroidectomy with postoperative 131I ablation and 100 healthy controls. Also, 50 randomly selected patients underwent laboratory assessment (including eNAMPT serum concentration by ELISA Assay Kit, TSH, free thyroid hormones, TSH-stimulated thyroglobulin Tg, antibodies – TgAbs, TPOAb) and body composition analysis twice: at admission and 6 months after being on suppressive levothyroxine doses. TSH-stimulated Tg of 1 ng/ml was defined as the cutoff value for predicting disease status as complete remission ( n = 55) and recurrent or persistent structural disease ( n = 45). Results: The visfatin serum concentrations in patients diagnosed with PTC and in healthy subjects were not statistically significantly different ( p = 0.9425). The eNAMPT levels were also similar in disease-free patients and the ones with tumour relapse. Besides, ROC curve analysis did not detect eNAMPT as a biomarker of PTC. Conclusion: We have not found visfatin as a potential serum marker of papillary thyroid cancer. Also, eNAMPT has no prognostic value in assessing the risk of disease recurrence or metastasis in PTC management.
First presentation of pyoderma gangrenosum in a patient with partial immunoglobulin A deficiency
Authors: Demirel S , Shetty M , Patel M , Mahmood K 
Published: April 2022

Summary We describe the case of a 58-year-old female with an intensely painful and rapidly enlarging necrotic cutaneous ulcer to the right shin on a background of partial immunoglobulin A deficiency (IgAD). She was seen by various healthcare professionals and managed with upscaling antibiotics for cellulitis requiring an inpatient hospital stay. The dermatology team made a clinical diagnosis of ulcerative Pyoderma Gangrenosum (PG) on assessing the patient 13 days post-onset of symptoms. The patient responded dramatically to steroids and oral tetracycline. This case highlights the unusually described association between PG and IgAD as well as the diagnostic challenge seen in patients presenting with PG.
A comparison of low-dose teicoplanin-loaded spacer application vs. high-dose vancomycin-and-gentamicin-loaded spacer application in the treatment of periprosthetic knee infection
Authors: Cimen Osman , Oner Ali , Koksal Alper , Dırvar Ferdi , Mert Muhammed , Şahin Mümine Nursu , Kargın Deniz 
Published: April 2022

Background/purpose In the current study, our aim was to compare the efficacy and biocompatibility of teicoplanin-loaded and vancomycin-and-gentamicin-loaded articulating spacers used in two-stage revision arthroplasty for eradication of periprosthetic knee joint infection. Methods In the current retrospective cohort study, there were 24 patients who were given 2 g or less antibiotics per 40 g of cement in the low-dose teicoplanin group, and 20 patients who were given a total of 3.6 g or more antibiotics per 40 g of cement in the high-dose vancomycin and gentamicin group. Two groups were compared statistically. Results There was no statistically significant difference in the treatment failure between the two groups (p = 0.488). No statistically significant differences were found in spacer fracture rates between the two groups (p = 0.802). Conclusion The current study has demonstrated that low-dose teicoplanin protocol is as effective and safe as high-dose vancomycin and gentamycin protocol.
A rare case of residual root myiasis caused by Clogmia albipunctata larvae (Diptera: Psychodidae)
Authors: Chen Juan , Liu Jinrui , Liu Yun , Liu Yingjie 
Published: April 2022

Abstract
Background
Dental injury caused by caries and trauma is the main cause of residual roots. Food trapped in the residual roots is difficult to clean. If the residual roots are not treated and cared for in time, flies can take advantage as soon as hygiene slips. Here, we present a rare case of human residual root myiasis caused by Clogmia albipunctata larvae, never previously reported.

Case presentation
A 26-year-old lady found two active, living larvae in her mouth while brushing her teeth. She did not present with fever, pain and any uncomfortable oral feeling. The intraoral examination revealed the right second mandibular molar was severely damaged as a result of caries, leaving a residual tooth root. The mucosa above it was mildly erythematous and edematous. No larvae and no inflamed gums were observed in her mouth. When normal saline was used to flush the area of the residual root with a syringe, four larvae appeared from the residual root. The larvae were observed by naked eye and under a light microscope. They were identified as the mature stage larvae of Clogmia albipunctata. Because the patient was in lactation, medication was not recommended. Treatment included the removal of all visible larvae followed by flushing the residual root with normal saline three times a day. The patient was followed-up weekly for one month. No more larvae were found and the erythematous and edematous mucosa healed completely.

Conclusions
The existence of a residual root can result in residual root myiasis. Myiasis caused by Clogmia albipunctata larvae or other fly larvae should be considered in cases of residual root infection.
Explaining variance in breastfeeding intentions and behaviors among a cohort of Midwest mothers using a theory of planned behavior-based structural model
Authors: Esquerra-Zwiers Anita , Goris Emilie Dykstra , Franzen Aaron 
Published: April 2022

AbstractBackgroundThe Theory of Planned Behavior (TPB) has guided the investigation of breastfeeding since the 1980’s, incorporating the major constructs of attitudes, subjective norms/normative beliefs, perceived behavioral control, and intentions.The purpose of this research study was to define a TPB-based structural latent variable model so as to explain variance in breastfeeding intentions and behaviors among a cohort of Midwest breastfeeding mothers.MethodsThe longitudinal descriptive study utilized questionnaire data collected from a convenience sample of 100 women with low-risk pregnancies with the intention to breastfeed at three separate time points (> 30 weeks antepartum, 10 and 60 days postpartum). Data were coded and analyzed using IBM SPSS, SAS and thelavaanpackage in R.ResultsParticipants were predominantly White (94%,n = 94), married (95%,n = 95), college-educated (96%,n = 96), and had previous breastfeeding experience (75%,n = 75). The majority gave birth vaginally (79%,n = 75). Varimax analysis revealed a plurality of factors within each domain. Attempts to fit a structural model, including both hierarchical and bi-factor latent variables, failed, revealing a lack of statistical significance and poor fit statistics.Conclusion(s)These findings illustrate the importance of using methods that fit the phenomena explained. Contributors to poor model fit may include outdated tools lacking cultural relevance, a change in social norms, or a failure to capture the possible influence of social media and formula marketing on breastfeeding behaviors. The null finding is a significant finding, indicating the need to revisit and refine the operationalization and conceptual underpinnings of the TPB through qualitative methods such as exploring the lived experiences of breastfeeding women in the Midwest region.