bluuebunny/crossref_metadata_2025_split huggingface dataset:
How childhood maltreatment links to labor values? The mediating role of moral competence and prosocial normative tendency
Authors: Gu Yuliang , Chao Xiaomei 
Published: June 2022

Abstract
Background
Labor values are important components of the individual value system and considered to be among the most important values of an individual, especially in China. In studies of values, childhood maltreatment is considered to have an important influence on the formation of individual values. However, there is no previous research about the relationship between childhood maltreatment and labor values. The mechanism of childhood maltreatment on labor values is not clear and requires further study.

Methods
This study intended to investigate the relationship between childhood maltreatment and labor values, and further verify whether moral competence or prosocial normative tendency mediated this correlation. Therefore, 2691 participants were recruited from primary and secondary schools, who completed Labor Values Scale, Childhood Trauma Questionnaire, Moral Competence subscale and Prosocial Norms subscale.

Results
Results revealed the negative correlation between childhood maltreatment and labor values. Importantly, childhood maltreatment also indirectly impacted labor values through moral competence and prosocial normative tendency. It indicated that both moral competence and prosocial normative tendency played a significant mediating role in this relationship. Our findings are valuable for understanding the underlying mechanism between early trauma and values.

Conclusions
Childhood maltreatment has important implications for labor values. Moral competence and prosocial normative tendency mediate between childhood maltreatment and labor values. The results remind us to pay attention to the important influence of childhood maltreatment in the cultivation of labor values, and focus on the role of moral competence and prosocial normative tendency.
Understanding the financial innovation priorities for renewable energy investors via QFD-based picture fuzzy and rough numbers
Authors: Li Wei , Yüksel Serhat , Dinçer Hasan 
Published: June 2022

AbstractThis study evaluates financial innovation priorities for renewable energy investors by generating a novel hybrid fuzzy decision-making model. First, SERVQUAL-based customer needs for financial innovation are weighted with decision-making trial and evaluation laboratory based on picture fuzzy sets. Second, the financial innovation priorities are ranked by technique for order preference by similarity to ideal solutions based on picture fuzzy rough sets. In this process, Theory of the solution of inventive problems-based technical characteristics for financial services, the process for innovative services, and competencies for financial innovation are considered using quality function deployment phases. In addition, the Vise Kriterijumska Optimizacija I Kompromisno Resenje method is also considered for an alternative ranking. Similarly, sensitivity analysis is also performed by considering five different cases. It is determined that the ranking priorities based on the proposed model are almost identical, demonstrating the proposed model’s validity and reliability. Assurance is the most crucial factor for the customer needs regarding the financial innovation priorities for renewable energy investors. Concerning the financial innovation priorities, the product is the essential priority for financial innovation; hence, it is recommended that companies engage qualified employees to effectively design the financial innovation for renewable energy investors. Additionally, necessary training should be given to the employees who currently work in the company, which can increase the renewable energy investors’ trust in the innovative financial products. Companies should mainly focus on the product to provide better financial innovation to attract renewable energy investors. An effectively designed financial innovation product can help solve the financing problem of renewable energy investors.
Identification of key apoptosis-related genes and immune infiltration in the pathogenesis of psoriasis
Authors: Zou Ailing , Kong Qingtao , Sang Hong 
Published: June 2022

Abstract
Background
Psoriasis is a condition in which skin cells build up and form itchy scales and dry patches. It is also considered a common lifelong disease with an unclear pathogenesis. Furthermore, an effective cure for psoriasis is still unavailable. Reductive apoptosis of keratinocytes and immune infiltration are common in psoriasis. This study aimed to explore underlying functions of key apoptosis-related genes and the characteristics of immune infiltration in psoriasis. We used GSE13355 and GSE30999 to screen differentially expressed apoptosis related genes (DEARGs) in our study. Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway, and gene set enrichment analysis (GSEA) were performed using clusterProfiler package. Protein–protein interaction (PPI) network was constructed to acquire key DEARGs. Transcription factor (TF)–target and miRNA–mRNA network analyses, drug sensitivity prediction, and immune infiltration were applied. Key DEARGs were validated using real-time quantitative PCR (RT-qPCR).

Results
We identified 482 and 32 DEARGs from GSE13355 and GSE30999, respectively. GO analysis showed that DEARGs were commonly enriched in cell chemotaxis, receptor ligand activity, and signaling receptor activator activity. KEGG pathway analysis indicated that viral protein interaction with cytokine and cytokine receptor was maximally enriched pathway. The GSEA analysis of GSE13355 and GSE30999 demonstrated a high consistency degree of enriched pathways. Thirteen key DEARGs with upregulation were obtained in the PPI network. Eleven key DEARGs were confirmed using RT-qPCR. Additionally, 5 TFs and 553 miRNAs were acquired, and three novel drugs were predicted. Moreover, Dendritic.cells.activated exhibited high levels of immune infiltration while Mast.cells.resting showed low levels of immune infiltration in psoriasis groups.

Conclusion
Results of this study may reveal some insights into the underlying molecular mechanism of psoriasis and provide novel targeted drugs.
Relationship between time of referral for physiotherapy and length of stay after stroke in a Nigerian tertiary hospital: a retrospective study
Authors: Aderonmu Joseph A. , Obembe Adebimpe O. 
Published: June 2022

AbstractBackgroundDespite the known benefits of physiotherapy, the relationship between its time of referral and the length of stay (LOS) of stroke patients in developing countries has been understudied. This relationship was investigated in this study as we determined the relationships between LOS and time of referral and LOS and the number of physiotherapy sessions received.MethodsMedical records of stroke patients admitted at Obafemi Awolowo University Teaching Hospitals Complex Ile-Ife between January 2007 and December 2016 were retrieved. Descriptive statistics were used to summarize the data, independent samplesttest, and one-way analysis of variance were used to determine differences, and Pearson correlation was used to determine relationships.ResultsA total of 585 medical records were retrieved. With an inpatient mortality rate of 40.7%, only 243 case records were included in the study. The mean LOS was 17 ± 13 days, and 63.4% received inpatient physiotherapy. Patients who were referred for physiotherapy (p= 0.019) and those who utilized physiotherapy (p= 0.001) had higher LOS. Also, there were significant correlations between LOS and the time of referral for physiotherapy (r= 0.575,p= 0.001) and LOS and the number of physiotherapy sessions received (r= 0.293,p= 0.001).ConclusionsStroke patients who utilized physiotherapy had longer LOS. The longer the time of referral and the higher the number of physiotherapy sessions, the longer the LOS. Early referral and commencement of physiotherapy optimize physiotherapy utilization, which may reduce the LOS of stroke patients.
Current trends in restrictive interventions in psychiatry: a European perspective
Authors: O'Donovan David , Boland Cailín , Carballedo Angela 
Published: June 2022

SUMMARYThis article reviews current evidence on the use of coercive measures, including seclusion and restraint, in psychiatric in-patient settings in Europe. There is a particular focus on evidence regarding the use of mechanical restraint. The review seeks to describe when the use of restrictive interventions such as restraint may be necessary, to explore the use of restraint in certain specialist settings and to investigate current laws and European policies on seclusion and restraint. The current rates of restraint in European psychiatric settings are explored, with a discussion of the limitations of the evidence currently available. The article discusses various consequences of seclusion and restraint, potential alternatives to their use and strategies to minimise their use and harm to patients. The use of coercive measures from an international context is considered, to provide context.
Whom Should We Screen for Cushing Syndrome? The Endocrine Society Practice Guideline Recommendations 2008 Revisited
Authors: Braun Leah T , Vogel Frederick , Zopp Stephanie , Marchant Seiter Thomas , Rubinstein German , Berr Christina M , Künzel Heike , Beuschlein Felix , Reincke Martin 
Published: June 2022

Abstract

Context
Cushing syndrome (CS) is a rare and serious disease with high mortality. Patients are often diagnosed late in the course of the disease.

Objective
This work investigated whether defined patient populations should be screened outside the at-risk populations defined in current guidelines.

Methods
As part of the prospective German Cushing registry, we studied 377 patients with suspected CS. The chief complaint for CS referral was documented. Using urinary free cortisol, late-night salivary cortisol, and the 1-mg dexamethasone suppression test as well as long-term clinical observation, CS was confirmed in 93 patients and ruled out for the remaining 284.

Results
Patients were referred for 18 key symptoms, of which 5 were more common in patients with CS than in those in whom CS was ruled out: osteoporosis (8% vs 2%; P = .02), adrenal incidentaloma (17% vs 8%, P = 0.01), metabolic syndrome (11% vs 4%; P = .02), myopathy (10% vs 2%; P &lt; .001), and presence of multiple symptoms (16% vs 1%; P &lt; .001). Obesity was more common in patients in whom CS was ruled out (30% vs 4%, P &lt; .001), but recent weight gain was prominent in those with CS. A total of 68 of 93 patients with CS (73%) had typical chief complaints, as did 106 of 284 of patients with ruled-out CS status (37%) according to the Endocrine Society practice guideline 2008.

Conclusion
The 2008 Endocrine Society Practice guideline for screening and diagnosis of CS defined at-risk populations that should undergo testing. These recommendations are still valid in 2022.
Spatiotemporal Explorations
Authors: Schneider-Vielsäcker Frederike 
Published: June 2022

Abstract
This article examines sociopolitical commentary in contemporary Chinese science fiction literature written by authors of the post-1980s generation. With a close reading of Hao Jingfang's 郝景芳 “Beijing zhedie” 北京折疊 (Folding Beijing, 2014) and Chen Qiufan's 陳楸帆 “Lijiang de yu'ermen” 麗江的魚兒們 (The Fish of Lijiang, 2006), the analysis focuses on how these works reflect the lived experience of ordinary urbanities in postmodern China and pays particular attention to the stories' engagement with the chronotope. This article argues that through the chronotope contemporary Chinese science fiction stories express unease about rapid transformation and visualize a divided Chinese society characterized by spatial disparity.
Safety and Outcomes of Combined Pancreatic and Hepatic Resections for Metastatic Pancreatic Neuroendocrine Tumors
Authors: Gudmundsdottir Hallbera , Pery Ron , Graham Rondell P. , Thiels Cornelius A. , Warner Susanne G. , Smoot Rory L. , Truty Mark J. , Kendrick Michael L. , Halfdanarson Thorvardur R. , Habermann Elizabeth B. , Nagorney David M. , Cleary Sean P. 
Published: June 2022

Abstract
Background
Approximately 40–50% of patients with pancreatic neuroendocrine tumors (pNETs) initially present with distant metastases. Little is known about the outcomes of patients undergoing combined pancreatic and hepatic resections for this indication.

Methods
Patients who underwent hepatectomy for metastatic pNETs at Mayo Clinic Rochester from 2000 to 2020 were retrospectively reviewed. Major pancreatectomy was defined as pancreaticoduodenectomy or total pancreatectomy, and major hepatectomy as right hepatectomy or trisegmentectomy. Characteristics and outcomes of patients who underwent pancreatectomy with simultaneous hepatectomy were compared with those of patients who underwent isolated hepatectomy (with or without prior history of pancreatectomy).

Results
205 patients who underwent hepatectomy for metastatic pNETs were identified: 131 underwent pancreatectomy with simultaneous hepatectomy and 74 underwent isolated hepatectomy. Among patients undergoing simultaneous hepatectomy, 89 patients underwent minor pancreatectomy with minor hepatectomy, 11 patients underwent major pancreatectomy with minor hepatectomy, 30 patients underwent minor pancreatectomy with major hepatectomy, and 1 patient underwent major pancreatectomy with major hepatectomy. Patients undergoing simultaneous hepatectomy had more numerous liver lesions (10 or more lesions in 54% vs. 34%, p = 0.008), but the groups were otherwise similar. Rates of any major complications (31% versus 24%, p = 0.43), hepatectomy-specific complications such as bile leak, hemorrhage, and liver failure (0.8–7.6% vs. 1.4–12%, p = 0.30–0.99), and 90-day mortality (1.5% vs. 2.7%, p = 0.62) were similar between the two groups. 5-year overall survival was 64% after combined resections and 65% after isolated hepatectomy (p = 0.93).

Conclusion
For patients with metastatic pNETs, combined pancreatic and hepatic resections can be performed with acceptable morbidity and mortality in selected patients at high-volume institutions.
Research Evaluating Staff Training Online for Resilience (RESTORE): Protocol for a single-arm feasibility study of an online Acceptance and Commitment Therapy intervention to improve staff wellbeing in palliative care settings
Authors: Finucane Anne , Hulbert-Williams Nicholas J , Swash Brooke , Spiller Juliet A , Lydon Brigid , Gillanders David 
Published: June 2022

Background: Palliative care staff commonly experience workplace stress and distress. General stressors include unmanageable workloads and staff shortages. Stressors specific to palliative care include regular exposure to death, loss and grief. The COVID-19 pandemic exacerbated exhaustion and burnout across the healthcare system, including for those providing palliative care. Evidence based psychological support interventions, tailored to the needs and context of palliative care staff, are needed. Acceptance and Commitment Therapy (ACT) is an established form of cognitive behavioural therapy which uses behavioural psychology, values, acceptance, and mindfulness techniques to improve mental health and wellbeing. ACT is effective in improving workplace wellbeing in many occupational settings. Our study examines the acceptability and feasibility of an online ACT-based intervention to improve mental health and wellbeing in staff caring for people with an advanced progressive illness. Methods: A single-arm feasibility trial. We will seek to recruit 30 participants to take part in an 8- week online ACT-based intervention, consisting of three synchronous facilitated group sessions and five asynchronous self-directed learning modules. We will use convergent mixed methods to evaluate the feasibility of the intervention. Quantitative feasibility outcomes will include participant recruitment and retention rates, alongside completion rates of measures assessing stress, quality of life, wellbeing, and psychological flexibility. Focus groups and interviews will explore participant perspectives on the intervention. We will run a stakeholder workshop to further refine the intervention and identify outcomes for use in a future evaluation. Results: We will describe participant perspectives on intervention acceptability, format, content, and perceived impact, alongside rates of intervention recruitment, retention, and outcome measure completion. Conclusion: We will show whether a brief, online ACT intervention is acceptable to, and feasible for palliative care staff. Findings will be used to further refine the intervention and provide essential information on outcome assessment prior to a full-scale evaluation.
Alcohol-induced inhibition of bone formation and neovascularization contributes to the failure of fracture healing via the miR-19a-3p/FOXF2 axis
Authors: Zhu Daoyu , Fang Haoyu , Yu Hongping , Liu Pei , Yang Qianhao , Luo Pengbo , Zhang Changqing , Gao Youshui , Chen Yi-Xuan 
Published: June 2022

Aims Alcoholism is a well-known detrimental factor in fracture healing. However, the underlying mechanism of alcohol-inhibited fracture healing remains poorly understood. Methods MicroRNA (miR) sequencing was performed on bone mesenchymal stem cells (BMSCs). The effects of alcohol and miR-19a-3p on vascularization and osteogenic differentiation were analyzed in vitro using BMSCs and human umbilical vein endothelial cells (HUVECs). An in vivo alcohol-fed mouse model of femur fracture healing was also established, and radiological and histomorphometric analyses were used to evaluate the role of miR-19a-3p. The binding of miR-19a-3p to forkhead box F2 (FOXF2) was analyzed using a luciferase reporter assay. Results miR-19a-3p was identified as one of the key regulators in the osteogenic differentiation of BMSCs, and was found to be downregulated in the alcohol-fed mouse model of fracture healing. In vitro, miR-19a-3p expression was downregulated after ethanol administration in both BMSCs and HUVECs. Vascularization and osteogenic differentiation were independently suppressed by ethanol and reversed by miR-19a-3p. In addition, the luciferase reporter assay showed that FOXF2 is the direct binding target of miR-19a-3p. In vivo, miR-19a-3p agomir stimulated callus transformation and improved the alcohol-impaired fracture healing. Conclusion This study is the first to demonstrate that the miR-19a-3p/FOXF2 axis has a pivotal role in alcohol-impaired fracture healing, and may be a potential therapeutic target. Cite this article: Bone Joint Res 2022;11(6):386–397.
Polarization-sensitive tunable extraordinary terahertz transmission based on a hybrid metal–vanadium dioxide metasurface
Authors: Badri S. Hadi , SaeidNahaei Sanam , Kim Jong Su 
Published: June 2022

Thermally tunable extraordinary terahertz transmission in a hybrid metal–vanadium dioxide (

V
O

2

) metasurface is numerically demonstrated. The metasurface consists of a metal sheet perforated by square loops, while the loops are connected with strips of

V
O

2

. The frequency and amplitude of the transmission resonance are modulated by controlling the conductivity of

V
O

2

. For a

y

-polarized incident field, the resonance transmission peak redshifts from 0.88 to 0.81 THz upon insulator-to-metallic phase transition of

V
O

2

. For an

x

-polarized incident field, the transmission resonance at 0.81 THz is observed in the insulator phase. However, in the metallic phase of

V
O

2

, the electromagnetic field is effectively reflected in the 0.5–1.1 THz range with a transmission level lower than 0.14. The proposed metasurface can be utilized as a terahertz modulator, reconfigurable filter, or switch.
Optical design optimization for improved lamp-reflector units in high-flux solar simulators
Authors: Martínez-Manuel Leopoldo , Peña-Cruz Manuel I. , Mutuberría Amaia , González Marcelino Sánchez 
Published: June 2022

High flux solar simulators are artificial solar facilities developed to imitate the on-sun operations of concentrating solar power technologies but under a well-controlled lab-scale environment. We report the optical enhancement of different high flux solar simulators for solar thermal and thermochemical applications. The solar simulator enhancement is numerically conducted by optimizing the geometry of ellipsoidal reflectors at focal lengths of 1600, 1800, and 2000 mm. The Monte Carlo ray-tracing technique is employed to evaluate the optical performance of different reflector designs. The typical seven-lamp solar simulator arrangement in hexagonal configuration is modeled to analyze the optical performance at different focal lengths. In addition, different xenon arc lamps are modeled with rated powers of 3000, 4000, 4500, and 5000 W for assessing the radiative flux characteristics of the proposed solar simulators. After the optimization, theoretical results show that peak fluxes and radiative powers of

7.2
−
14

.

3

M
W

/

m

2

and 5.06–10.4 kW, respectively, can be achieved with the proposed designs of solar simulators for the different rated powers. Compared with a commercial reflector, theoretical peak flux and power can be improved up to 36% and 17.9%, respectively, with the proper combination of lamp-reflector units. We provide design alternatives to select a more suitable light source at low-rated powers (

≤

5000

W

) and different focal lengths of the reflector, which simplifies the complexity of the design and improves the performance of solar simulators.
Teachers’ perceptions of teaching physical education using online learning during the COVID-19: A quantitative study in Turkey
Authors: Konukman Ferman , Filiz Bijen , Ünlü Hüseyin 
Published: June 2022

Introduction
This quantitative study aimed to determine physical education teachers’ (PETs) perceptions of online physical education (OLPE) during the COVID-19 pandemic in Turkey.

Methods
An OLPE teaching survey during the COVID-19 was used, comprising PETs’ opinions on OLPE teaching as well as the advantages, disadvantages, difficulties, and suggestions for OLPE teaching.

Results
A significant difference by gender was identified in the individual approach to student learning, greater student independence, and ongoing monitoring of student results for teachers, parents, and students. In addition, a significant difference was found by gender in the difficulty in implementing the core curriculum content as well as by school type in the lack of proper home equipment, absence of or limited Internet access, and problems with connecting the computer, tablet, or smartphone to the Internet. Moreover, PETs stated that OLPE teaching is not only the best way to transfer basic information, but it also gives them an opportunity to learn digital technology by devoting time for research for self-improvement. However, they stated that students do not perceive OLPE as a lesson, as student participation is lacking. Moreover, there are deficiencies in students’ social-emotional development. They also stated that the content of the lessons was insufficient, and they were unable to make the lesson interesting.

Conclusion
PETs’ suggested recommendations included enriching the course content, increasing the lesson time, developing a new curriculum, and creating a platform to access course resources.