bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations of non-HDL-C and triglyceride/HDL-C ratio with coronary plaque burden and plaque characteristics in young adults
Authors: Akin Fatih , Altun İbrahim , Ayca Burak , Kose Nuri , Altun İlknur 
Published: May 2022

Coronary artery disease (CAD) is uncommon in young adult patients. However, these patients have different risk factor profiles and high-risk coronary plaques are more common. The aim of this study was to examine the relations between the coronary plaque burden, plaque composition, serum non-high-density lipoprotein cholesterol (non–HDL-C) levels, and triglyceride/high-density lipoprotein cholesterol (TG/HDL-C) ratio in young adults. We analyzed a total of 551 patients under age 45 who had undergone coronary computed tomography angiography (CCTA). Coronary plaque characteristics were analyzed using CCTA. Multivariate linear regression analysis was used to assess the predictors of non-calcified plaque (NCB) and calcified plaque (CB) burdens. Serum non–HDL-C levels and TG/HDL-C ratio were higher in the coronary atherosclerosis patient group. Serum non–HDL-C levels and the TG/HDL-C ratio were higher in the obstructive CAD patient group. The plaque burden was positively correlated with non-HDL-C (r = 0.30; p < 0.001), and TG/HDL-C ratio (r = 0.18; p < 0.001). NCB was positively correlated with age, gender, smoking status, fasting blood glucose, total cholesterol, low-density lipoprotein cholesterol, serum triglycerides, hbA1c, non–HDL-C, and TG/HDL-C ratio. Non–HDL-C (β coefficient = 0.13; p = 0.023) and TG/HDL-C ratio (β = 0.10; p = 0.042) were independent predictors of NCB. Serum non–HDL-C levels and TG/HDL-C were significantly associated with the presence and burden of coronary plaques. Serum non–HDL-C and TG/HDL-C ratios were independently associated with NCB, suggesting their use as easy-to-compute markers for identifying high-risk groups in young adults.
Features of changes in hormonal homeostasis among patients with acne
Authors: Elkin V. D. , Kobernik M. Yu. , Sedova T. G. , Kuznetsov I. D. 
Published: May 2022

Objective. To evaluate the nature of changes in hormonal homeostasis among patients with acne, depending on menstrual function disorders. Acne is a common skin disease characterized by the development of an inflammatory process in the sebaceous glands; at the age of 1224, it is equally observed in boys and girls, and at an older age, it mainly affects women. Acne has a complex pathogenesis, in which hereditary, metabolic, immune and endocrine mechanisms are realized. It is often found in women with a violation of menstrual function. The aim of the study was to evaluate the nature of changes in hormonal homeostasis among patients with acne, depending on menstrual function disorders.
Materials and methods. The study involved 65 patients with acne, who were divided into two groups: group I was formed by 40 patients with acne having menstrual disorders; group II included 35 patients with acne without menstrual function disorders. The groups were comparable by social status and age; all were residents of the Perm Region, all gave voluntary written consent to participate in the study. The study included general clinical techniques, dermatological status and laboratory methods including biochemical blood analysis with indicators of lipid spectrum, glucose, total protein, zinc, liver enzymes, pituitary hormones (FSH, LH, TSH, prolactin) and sex hormones. Methods of parametric and nonparametric statistics were used to analyze the data obtained.
Results. In patients with acne, minor metabolic changes were detected, equally with and without menstrual cycle disorders. In the study of hormonal homeostasis, it was noted that in acne patients with menstrual cycle disorders, hyperprogesteronemia was determined much more often (80.0 6.3 %). The remaining sex hormones and pituitary hormones had insignificant changes in both the groups studied.
Conclusions. Acne, accompanied by a disturbance of menstrual function, is characterized by change in hormonal homeostasis in the form of an increased level of blood progesterone. In acne patients with a normal menstrual cycle, hormonal changes are insignificant. The metabolic disorders observed in acne do not depend on the character of the menstrual cycle. Patients with acne having menstrual dysfunction require joint management and treatment by both dermatovenerologist and gynecologist. In other cases, dermatological tactics is the basic one.
Violation of supporting function of feet in children with hip subluxation of dysplastic genesis
Authors: Nikityuk I. E. , Bortulev P. I. , Vissarionov S. V. , Savina M. V. 
Published: May 2022

Objective. To study the plantographic characteristics of the feet in children with unilateral dysplastic hip subluxation (DHS) and to analyze the patterns of plantar pressure distribution on the affected and intact sides.
Material and methods. A biomechanical study was conducted in 23 children, aged 13 to 17 years, with unilateral DHS of Crowe group I. The plantographic characteristics of the feet were evaluated and their relationship with the vertical balance of the patients body was analyzed. The control group consisted of 18 healthy children of the same age.
Results. In patients with unilateral DHS, there is a significant decrease in all indices of support: anterior t, medial m and median s compared with healthy children, not only on the foot of the affected limb, but also on the intact side. It indicates a deterioration in the spring function of the transverse and longitudinal arches of the feet due to their rigidity. The foot on the affected lower limb has a pathologically increased Clarke's angle , which indicates an increase in the height of the longitudinal arches of the foot, which leads to a decrease in the total area of its support. In patients, there is a pathological increase in comparison with the norm of functional relationships between the arches of the foot on the affected and intact lower extremities, that is a sign of a formed pathological foot support strategy.
Conclusions. The pathological supporting strategy of the feet on the affected and intact lower extremities in patients with unilateral DHS may be a consequence of a violation of the global sagittal balance of the body, leading to an adaptive reaction of the musculoskeletal system in response to compensatory changes in the links of the kinematic chain "spine-pelvis".
Diagnostics of bronchial obstruction syndrome with portal wheezing detector in children
Authors: Kalinina N. M. , Furman E. G. , Sokolovskiy V. L. 
Published: May 2022

Objective. To determine the efficiency of diagnostics of the clinical syndrome of bronchial obstruction with WheezeScan detector in children, to assess the sensitivity and specificity of this method. Electronic medical devices used for registration and analysis of breath sounds can help to diagnose different syndromes in pediatric pulmonology.
Materials and methods. The study involved 15 children aged 1 to 17 years, who were hospitalized to Pulmonology Unit of the Regional Childrens Clinical Hospital. The children were divided into two groups depending on the presence or absence of wheezes in auscultation. The detector WheezeScan HWZ-1000T-E (Omron) was used to study the presence of wheezes. The control group included children without any objective signs of bronchial obstruction.
Results. It was detected while examining children that in auscultation 20 % (n=3) of children had dry wheezes, and in detector diagnostics the result was positive in 100 % of cases. In auscultation, 80 % (n=12) of children did not show clinically marked bronchial obstruction syndrome, the result of WheezeScan detector was 73 % (n=11). Diagnostic sensitivity and specificity was 100 %.
Conclusions. Screening diagnostics of bronchial obstruction syndrome in children by means of electronic detector of wheezing is effective and can be applied for ambulatory patients of different ages in a pediatric hospital unit.
PENGARUH KETERLIBATAN KERJA TERHADAP ORGANIZATIONAL CITIZENSHIP BEHAVIOR PADA KARYAWAN ROKOK DI MALANG
Authors: Ilhamiyah Layyinatul , Harsono Yudi Tri 
Published: May 2022

Abstract: This study aimed to determine the effect of job involvement on the organizational citizenship behavior on cigarette employees in Malang. This research hypothesis is that job involvement affect the organizational citizenship behavior on cigarette employees in Malang. The subjects of this study are 53 employees at cigarette company Malang. The data collection technic used in this study is a questionnaire consisting of 2 scales, namely job involvement scale and organizational citizenship behavior scale. The job involvement scale consists of 12 items constructed by the researcher based on the job involvement aspect proposed by Kanungo (Ansel and Wijono, 2012), the organizational citizenship behavior scale consists of 17 items constructed by researcher based on the organizational citizenship behavior aspect proposed by Organ, Podsakoff, and Mackenzie (Titisari, 2014). The result of the analysis of research data for hypothesis testing using simple linear regression analysis is that there is a significant effect of job involvement and organizational citizenship behavior of Malang cigarette company employees of 22,3 percent with a significance value of (p) less than 0,05

Abstrak: Penelitian ini bertujuan untuk mengetahui pengaruh keterlibatan kerja terhadap organizational citizenship behavior pada karyawan rokok di Malang. Hipotesis penelitian ini adalah terdapat pengaruh keterlibatan kerja terhadap organizational citizenship behavior pada karyawan rokok di Malang. Subjek penelitian ini adalah 53 karyawan rokok di Malang. Teknik pengambilan data pada penelitian ini menggunakan kuesioner yang terdiri dari 2 skala, yaitu skala keterlibatan kerja dan skala organizational citizenship behavior (OCB). Skala keterlibatan kerja terdiri dari 12 butir aitem yang dikonstruksikan oleh peneliti berdasarkan aspek keterlibatan kerja yang dikemukakan oleh Kanungo (Ansel dan Wijono, 2012), dan skala organizational citizenship behavior (OCB) terdiri dari 17 butir aitem yang dikonstruksikan oleh peneliti berdasarkan aspek organizational citizenship behavior (OCB) yang dikemukakan oleh Organ, Podsakoff, dan Mackenzie (Titisari, 2014). Analisis data penelitian untuk pengujian hipotesis menggunakan regresi linier sederhana, hasilnya terdapat pengaruh yang signifikan keterlibatan kerja terhadap organizational citizenship behavior (OCB) pada karyawan rokok di Malang sebesar 22,3 persen dengan nilai signifikansi (p) kurang dari 0,05.
HUBUNGAN ANTARA HARDINESS DENGAN RESILIENSI PADA PENGUSAHA MUDA ANGGOTA HIPMI CABANG KOTA MALANG
Authors: Nuroso Gilang Ramadhan Indra Jaya , Harsono Yudi Tri 
Published: May 2022

Abstract: This study aims to determine the relationship between hardiness and resilience in young entrepreneurs HIPMI’s members at Malang brach. This research hypothesizes that there is a relationship between hardiness and resilience in young entrepreneurs HIPMI’s members. The subjects of this research are 79 young entrepreneurs HIPMI’s members at Malang branch. The data collection method in this study used a questionnaire consisting of two scales, namely the hardiness scale and the resilience scale. The hardiness scale consisting of 45 items was developed by Kobasa, (1979) then modified by Bartone, (1995) and adapted by the authors, namely the Dispositional Resilience Scale-45 (DRS-45) and the Resilience Quotient (RQ) consisting of 56 items were developed by Reivich and Shatte, (2002) and adapted by the authors. Analysis of research data to test the hypotesis using Pearson’s product-moment correlation resulted in a significant correlation coefficient between hardiness and resilience in young entrepreneurs HIPMI’s members and included a high with unidirectional category of 0.609 with a significance values of (p) less than 0.05.
Abstrak: Penelitian ini bertujuan untuk mengetahui hubungan antara hardiness dengan resiliensi pada pengusaha muda anggota HIPMI cabang kota Malang. Hipotesis ada penelitian ini adalah terdapat hubungan positif antara hardiness dengan resiliensi pada pengusaha muda anggota HIPMI Cabang kota Malang. Penelitian ini menggunakan 79 subjek yang tergabung dalam HIPMI cabang kota Malang dengan berbagai variasi usaha. Metode pengambilan data dalam penelitian ini menggunakan kuesioner yang terdiri dua skala penelitian yaitu Dispositional Resilience Scale dengan 26 aitem untuk mengukur Hardiness oleh Kobasa (1979) yang kemudian di modifikasi oleh Bartone (1989) dan Resilience Quotient (RQ) scale dengan 42 aitem untuk mengukur resiliensi yang disusun oleh Reivich and Shatte (2002). Analisis data penelitian untuk pengujian hipotesis menggunakan metode Pearson’s product moment correlation, hasilnya terdapat hubungan signifikan hardiness dengan resiliensi pada pengusaha muda anggota HIPMI cabang kota Malang dan termasuk dalam kategori tinggi dengan arah positif sebesar 0,609 dengan nilai signifikansi (p) kurang dari 0,05.
Clobetasol propionate 0.025%: a topical therapeutic for skin diseases
Authors: Sadana Jatinder K. , Rai Anshuman , Sethi Meenu , Khanna Deepshikha , Jain Suresh K. , Bharti Rakesh , Bhoira Salman S. , Dhamija Ashish , Nabar Kiran V. , Banjara Naresh K. 
Published: May 2022

The most widely recommended drugs for the treatment of a variety of dermatoses are topical corticosteroids (TC). These medications are approved for the treatment of inflammatory and pruritic manifestations of dermatologic disorders due to their powerful, symptom-relieving impact. Clobetasol propionate (CP) is the most popular TC used to relieve itching, redness, and edema caused by skin disorders. Topical corticosteroids exhibit anti-inflammatory, anti-pruritic, and vasoconstrictive activities. Clobetasol propionate binds to cytoplasmic glucocorticoid receptors and activates glucocorticoid receptor-mediated gene expression, resulting in the production of anti-inflammatory proteins and suppression of the production of inflammatory mediators. The effectiveness, safety, and clinical experience of utilizing CP 0.025% topical therapy for the treatment of various dermatologic disorders are discussed in this case series.
The Chosen Child: Characteristics of Family Caregivers Selected at an Early Age to Provide Care to Their Parents
Authors: Campione Joanne R. , Zebrak Katarzyna A. 
Published: May 2022

AbstractBackground and ObjectiveFamily caregivers who have been chosen by their family for the caregiving role may be under a unique type of stress due to familism and/or lack of choice. The purpose of this exploratory analysis was to investigate the characteristics of family caregivers who self‐identified as the “Chosen Child” caregiver.MethodsWe used survey data from 652 child caregivers collected in December 2016 as part of the outcome evaluation of the National Family Caregiver Support Program (NFCSP). We compared the characteristics between the caregivers who responded “definitely true” when asked if they were chosen by their family as a child to provide care (“Chosen Child”) and the caregivers who answered “definitely false” to chosen child (DFCC).ResultsCompared to DFCC caregivers (n=214), Chosen Child caregivers (n=168) experienced emotional distress more often (p=0.009), were more likely to have annual household income ≤$40,000 (p=0.018), were less likely to be employed (p=0.009), and were less likely to have received respite care in the past 6 months from family or friends (p=0.009). The mean emotional distress score remained significantly different between Chosen Child and DFCC caregivers after adjusting for potential confounders (2.64 vs. 2.43, respectively).ConclusionFamily and friends should be aware that the Chosen Child caregiver may be at risk for emotional distress and may be hesitant to ask for respite care or other types of support. Interventions for the Chosen Child should help them seek support when needed.
Residents' and Family Perspectives of Involuntary Healthcare Facility Closure and Relocation
Authors: Weaver Raven H. , Roberto Karen A. , Brossoie Nancy , Teaster Pamela B. 
Published: May 2022

AbstractOlder adults who receive care in a healthcare facility certified by the Centers for Medicare and Medicaid Services receive services mandated and regulated by state and federal policy to ensure that basic quality and safety standards are met. Termination of certification due to ongoing care deficiencies results in the involuntary relocation of residents receiving Medicare or Medicaid services to another healthcare facility. If a facility ultimately closes, all residents are displaced. Facility decertification happens infrequently, but when it does occur, it affects both residents and their families. Few studies have examined resident input and the role that family plays in the relocation process. The purpose of this study was to explore residents' and families' perceptions of the relocation process and its effect on residents' health and wellbeing. The study sample included 27 residents and 93 family members from two facilities that lost their certification. Semi‐structured, audio‐recorded interviews conducted with participants either in‐person or by telephone focused on perceptions of relocation processes, relocation challenges and stressors, and physical and mental effects on residents. Interviews were transcribed verbatim and analyzed using an open coding process to identify common themes and patterns in the data. Four interrelated, overarching themes emerged from the analysis: 1) awareness of need to relocate; 2) notification of need to relocate; 3) involvement in relocation decisions; and 4) relocation stressors. Neither residents nor families were satisfied with the relocation process and offered multiple suggestions to guide policy and practice to improve their involuntary relocation experiences.
Why Don't Older Adults Use Senior Centers? Evidence from Adults Age 50 and Older in Massachusetts
Authors: Somerville Ceara , Roldán Nidya Velasco , Bui Cindy N. , Coyle Caitlin , Mutchler Jan 
Published: May 2022

AbstractSenior centers are crucial community resources, providing programs and services intended to meet a range of needs and interests among older adults and serving as community hubs for social connection with peers. This study aims to compare older adults who attend senior centers to those who do not and assess reasons for non‐attendance. Secondary data pooled from community needs assessment surveys includes a sample of 8,573 community‐dwelling adults aged 50 and older from eight communities in Massachusetts. Three‐quarters of respondents reported not attending the senior center. The most common reasons selected for non‐attendance are not being interested (26%) and not feeling “old enough” (27%). There are significant differences among age groups for all reasons given for non‐attendance. Moreover, there are significant gender differences among most reasons given. This study suggests that senior centers and policies supporting senior centers may increase participation by expanding outreach and marketing efforts to include older men and those aged 60‐69, and by adapting programming that appeals to different age groups and changing interests of older adults. Results suggest that adjusting hours of operation may offer those aged 60‐69 a better opportunity to participate at the senior center. This research indicates an opportunity for reevaluating and updating senior center operations to reflect current interests and more effectively attract and serve an evolving older population.
Efficacy of levamisole with standard care treatment vs. standard care in clinical presentations of non-hospitalized patients with COVID-19: a randomized clinical trial
Authors: Asgardoon Mohammad Hossein , Emadi Koochak Hamid , Kazemi-Galougahi Mohammad Hassan , Zare Dehnavi Ali , Khodaei Behzad , Behkar Atefeh , Dehpour Ahmad Reza , Khalili Hossein , Aminianfar Mohammad 
Published: May 2022

Objective: The aim of this study was to evaluate the influence of adding a 10-day course of levamisole (LVM) to the standard care compared with standard care alone, on the clinical status of COVID-19 patients with mild to moderate disease.
Methods: In this randomized open-label trial, we enrolled non-hospitalized patients with mild to moderate COVID-19 at nine health centers in Tehran province, Iran, in 2021. Patients were randomly assigned to receive a 10-day course of LVM with standard care (n=185) or standard care alone (n=180) in a 1:1 ratio. On days 1 to 10, LVM was administered orally at a dosage of 50 mg. The participants were called and followed on days 1, 3, 5, 7, 9, and 14. The measured parameters were general health condition, hospitalization rate, signs and symptoms, and adverse events. The generalized estimating equations model was used for analysis.
Results: Among 507 randomized patients, 473 patients started the experiment and received LVM plus standard care or received the standard care alone; 385 patients included in the analysis; 346 (98%) patients completed the trial. The median age of the patients was 40 years [IQR: 32-50.75]; and ‎201 (55.1%)‎ patiens were male. The mean age, sex ratio, and frequency of the underlying diseases of the patients in the two study groups had no ‎statistically significant differences (P>0.05). Compared to the control group, LVM improved the general health condition of the patients (B=-0.635; 95% CI: -0.041,-0.329; P<0.001). Patients receiving LVM compared with standard care group had significantly lower odds of developing fever (OR=0.260; 95% CI: 0.11‎‎3‎,0.59‎‎9‎; P=0.002), chills (OR=0.223; 95% CI:‎‎ 0.07‎‎6,‎0.64‎‎8‎; P= 0.006), fatigue (OR=0.576; 95% CI:‎ 0.34‎‎6,‎0.96‎‎0‎‎; P=0.034), and myalgia (OR=0.54‎‎4‎; 95% CI:‎ 0.31‎‎7‎,0.93‎‎2‎‎; P=0.027). No significant difference was observed in the rate of hospitalization. Although the intervention group had greater adverse effects than the control group, the difference was not statistically significant.
Conclusion: Findings of this study suggest that LVM has clinical benefits in improving patients’ health condition with mild to moderate COVID-19.
Early clinical experience with a new Video Laryngoscope (SANYAR®) for tracheal intubation in adults: A comparison clinical study
Authors: Khajavi Mohammad Reza , Mohammadyousefi Rana , Neishaboury Mohamadreza , Shariat Moharari Reza , Etezadi Farhad , Pourfakhr Pejman 
Published: May 2022

Objective: SANYAR® video laryngoscope (S-VL) is a new video laryngoscope. We conducted a comparative clinical study to assess its ability to provide laryngeal exposure and facilitate endotrachetal intubation (ETI) in adult patients.
Methods: This comparison clinical study was conducted on adult patients undergoing elective general anesthesia. The patients were randomly divided into two groups of direct laryngoscopy (DL) or S-VL. The primary outcome was the time required for performing ETI. The glottic view and successful ETI on the first attempt was also compared between the two groups.
Results: Full and partial glottic visualization was achieved in 100% of the patients in the S-VL group, while the corresponding figure in the DL group was 90%. Cormack-Lehane III was observed in 5 patients of the DL group, and ETI was successfully carried out with S-VL. The first-pass success rate of ETI was significantly higher in S-VL group compared to the DL group (94% vs. 78%; P = 0.034). The mean times to ETI were 38.32±6.4 and 35.31±8.4 seconds in DL and S-VL groups, respectively (P = 0.650).
Conclusions: During ETI for general anesthesia, SANYAR® video laryngoscope compared with direct laryngoscopy improved glottic visualization and first-pass ETI rate.