bluuebunny/crossref_metadata_2025_split huggingface dataset:
Approaching Dianionic Tetraoxadiborecine Macrocycles: 10‐Membered Bora‐Crown Ethers Incorporating Borafluorenate Units
Authors: Wentz Kelsie E. , Molino Andrew , Freeman Lucas A. , Dickie Diane A. , Wilson David J. D. , Gilliard Robert J. 
Published: November 2022

AbstractThe addition of non‐benzenoid quinones, acenapthenequinone or aceanthrenequinone, to the 9‐carbene‐9‐borafluorene monoanion (1) affords the first examples of dianionic 10‐membered bora‐crown ethers (2–5), which are characterized by multi‐nuclear NMR spectroscopy (1H,13C,11B), X‐ray crystallography, elemental analysis, and UV/Vis spectroscopy. These tetraoxadiborecines have distinct absorption profiles based on the positioning of the alkali metal cations. When compound4, which has a vacant C4B2O4cavity, is reacted with sodium tetrakis[3,5‐bis(trifluoromethyl)phenyl]borate, a color change from purple to orange serves as a visual indicator of metal binding to the central ring, whereby the Na+ion coordinates to four oxygen atoms. A detailed theoretical analysis of the calculated reaction energetics is provided to gain insight into the reaction mechanism for the formation of2–5. These data, and the electronic structures of proposed intermediates, indicate that the reaction proceeds via a boron enolate intermediate.
Mitigating Electron Leakage of Solid Electrolyte Interface for Stable Sodium‐Ion Batteries
Authors: Wang Enhui , Wan Jing , Guo Yu‐Jie , Zhang Qianyu , He Wei‐Huan , Zhang Chao‐Hui , Chen Wan‐Ping , Yan Hui‐Juan , Xue Ding‐Jiang , Fang Tiantian , Wang Fuyi , Wen Rui , Xin Sen , Yin Ya‐Xia , Guo Yu‐Guo 
Published: November 2022

AbstractThe interfacial stability is highly responsible for the longevity and safety of sodium ion batteries (SIBs). However, the continuous solid‐electrolyte interphase(SEI) growth would deteriorate its stability. Essentially, the SEI growth is associated with the electron leakage behavior, yet few efforts have tried to suppress the SEI growth, from the perspective of mitigating electron leakage. Herein, we built two kinds of SEI layers with distinct growth behaviors, via the additive strategy. The SEI physicochemical features (morphology and componential information) and SEI electronic properties (LUMO level, band gap, electron work function) were investigated elaborately. Experimental and calculational analyses showed that, the SEI layer with suppressed growth delivers both the low electron driving force and the high electron insulation ability. Thus, the electron leakage is mitigated, which restrains the continuous SEI growth, and favors the interface stability with enhanced electrochemical performance.
Metal‐Free Intermolecular C−H Borylation of N‐Heterocycles at B−B Multiple Bonds
Authors: Brückner Tobias , Ritschel Benedikt , Jiménez‐Halla J. Oscar C. , Fantuzzi Felipe , Duwe Dario , Markl Christian , Dewhurst Rian D. , Dietz Maximilian , Braunschweig Holger 
Published: November 2022

AbstractCarbene‐stabilized diborynes of the form LBBL (L=N‐heterocyclic carbene (NHC) or cyclic alkyl(amino)carbene (CAAC)) induce rapid, high yielding, intermolecular ortho‐C−H borylation at N‐heterocycles at room temperature. A simple pyridyldiborene is formed when an NHC‐stabilized diboryne is combined with pyridine, while a CAAC‐stabilized diboryne leads to activation of two pyridine molecules to give a tricyclic alkylideneborane, which can be forced to undergo a further H‐shift resulting in a zwitterionic, doubly benzo‐fused 1,3,2,5‐diazadiborinine by heating. Use of the extended N‐heteroaromatic quinoline leads to a borylmethyleneborane under mild conditions via an unprecedented boron‐carbon exchange process.
Case‐Mix Moderation of the Relationship Between OR Performance Metrics and Utilization
Authors: Elliott‐Dawe Cheryl , Chen Jie , Zadinsky Julie K. 
Published: November 2022

ABSTRACTWe investigated the impact of the case‐mix ratio of inpatients to outpatients on the relationships between OR utilization and late starts, turnover time, delays, cancellations, and idle time at an academic medical center in the southeastern United States. After extracting 55 months of data from the surgical repository, we used simple and multiple linear regression models to analyze the data and determine the strength and direction of the relationships among the variables. We compared models comprising proportionally more inpatients to models comprising proportionally more outpatients for each metric to ascertain the effects of case mix on OR utilization. Idle time had the greatest effect on OR utilization, followed by late starts and turnover time. Case mix moderated the relationship between OR utilization and the metrics of cancellations and turnover time. Perioperative leaders may enhance OR utilization by monitoring and addressing idle time and late starts and scheduling an appropriate mix of inpatients and outpatients.
Surgical Conscience: A Concept Analysis for Perioperative Nurses
Authors: Quintana Danielle 
Published: November 2022

ABSTRACTA concept analysis was performed on surgical conscience in perioperative nursing using the Penrod and Hupcey principle‐based method. The analysis included framing surgical conscience according to the epistemological, pragmatic, linguistic, and logical principles and showed that surgical conscience falls into several domains, including nursing, surgery, anesthesiology, surgical technology, and interventional radiology. Although some perioperative nurses consider surgical conscience a fundamental principle in the OR, there is limited published literature on how surgical conscience is introduced, learned, improved, or measured. The literature search for this concept analysis did not produce a published operationalization of the concept. Therefore, this concept analysis provides a comprehensive definition of surgical conscience to guide the future research that is needed to reinforce surgical conscience and prevent conceptual dogma—a situation in which attributes of a concept lack the support of additional investigation but are still used and reinforced over time.
Prediction of intensity of dispersion in surfactant solutions in vertical sparged bubble column
Authors: Parmar Rajeev 
Published: November 2022

AbstractDispersion of liquid in bubble column is an important process in chemical and allied industries. In the present work, the dispersion characteristics of liquid phase in a bubble column is studied in three different surfactant solutions. A comparative analysis on the dispersion characteristics of liquid phase in different surfactants has been carried out. The gas holdup and mixing time are also analysed. The effect of different physiochemical properties and operating variables on the dispersion coefficient and gas holdup is examined. A novel model for the estimation of dispersion due to bubble motion has been developed which incorporates the effect of gas holdup, liquid viscosity and circulation velocity. The contribution of dispersion coefficient due to the bubble motion in overall dispersion is also examined. The value of velocity distribution parameter in three different surfactant solutions is also compared. Generalised correlations for gas holdup, dispersion coefficient and mixing time are also developed based on the physicochemical properties of liquid. This research may be useful for the selection and application of these three surfactants in industries. This article will also help researchers for designing multiphase flow system where role of dispersion due to the motion of bubbles is significant.
Inhibition of ferroptosis of renal tubular cells with total flavones of Abelmoschus manihot alleviates diabetic tubulopathy
Authors: Wang Mei‐Zi , Cai Yu‐Feng , Fang Qi‐Jun , Liu Ying‐Lu , Wang Jie , Chen Jia‐Xin , Fu Yan , Wan Bing‐Ying , Tu Yue , Wu Wei , Wan Yi‐Gang , Mu Geng‐Lin 
Published: November 2022

AbstractFerroptosis‐related renal tubular lesions play important roles in diabetic kidney disease (DKD) progression, and these pathophysiological responses are collectively described as diabetic tubulopathy (DT), which lacks an effective treatment. Total flavones from Abelmoschus manihot (TFA), a natural extract that extensively used in patients with chronic kidney disease, has been used for treatment of renal tubular injury in DKD; however, whether TFA alleviates DT and its potential mechanisms remain unclear. Hence, we investigated the effects of TFA, compared to dapagliflozin, in DT management both in vivo and in vitro, using a DKD rat model and the NRK‐52 E cells. Following modeling, the DKD rats received TFA, dapagliflozin, or vehicle for 6 weeks. For the in vitro research, the NRK‐52 E cells were exposed to advanced glycation end products (AGEs) plus ferrostatin‐1 (Fer‐1), dapagliflozin, or TFA. Changes in biochemical parameters and renal tubular injury were analyzed in vivo, while changes in ferroptosis of renal tubular cells and the ferroptosis‐related proteins expression were analyzed both in vivo and in vitro. We found that TFA and dapagliflozin improved biochemical parameters, renal tubular injury, and ferroptosis in the DKD rats. Moreover, TFA and dapagliflozin inhibited ferroptosis by ameliorating iron deposition, lipid peroxidation capacity, and ferroptosis‐related proteins expression in vitro, which was similar to the effects of Fer‐1. Collectively, this study demonstrated that TFA treated DT in a manner similar to dapagliflozin by inhibiting ferroptosis of renal tubular cells via improving iron deposition and antioxidant capacity. Our findings provide new pharmacological evidence for TFA application in DT treatment.
Sexual functioning among breast cancer survivors and non‐cancer controls over 5 years post diagnosis: Pink SWAN
Authors: Avis Nancy E. , Crawford Sybil L. , Gold Ellen B. , Greendale Gail A. 
Published: November 2022

AbstractPurposeTo compare sexual functioning from diagnosis to 5 years post diagnosis among breast cancer survivors (BCS) and women without cancer (controls).Patients and MethodsAnalyses included 118 BCS and 1765 controls from 20 years of the longitudinal Study of Women's Health Across the Nation (SWAN), a multiracial/ethnic cohort of mid‐life women assessed approximately annually from 1995 to 2015. Pink SWAN participants reported no cancer at SWAN enrollment and developed (BCS) or did not develop (controls) incident breast cancer after enrollment. Outcomes included: being sexually active or not, intercourse frequency, sexual desire, vaginal dryness, and pain with intercourse. Using longitudinal logistic regression, we compared BCS and controls on prevalence of sexual functioning outcomes with respect to years since diagnosis. In addition, we examined whether menopause transition stage, depressive symptoms, relationship satisfaction, vaginal dryness, or pain with intercourse modified the relation between breast cancer and sexual functioning outcomes.ResultsAdjusting for partner status, both BCS and controls reported similar declines over time in being sexually active, sexual intercourse frequency, and sexual desire. Among sexually active women, more BCS than controls consistently reported vaginal dryness with significant differences between 2 and 4 years post‐diagnosis, and pain with intercourse, with statistically significant differences between 0.5 years post‐diagnosis to 2 years post‐diagnosis. Being post‐menopausal and reporting depressive symptoms were significant effect modifiers for pain with intercourse with both variables having positive and stronger associations with pain among the controls than among BCS.ConclusionExcept for more reporting of vaginal dryness and pain with intercourse among BCS, negative changes in sexual function during mid‐life were similar in those with and without breast cancer.
Mutation patterns and evolutionary action score of TP53 enable identification of a patient population with poor prognosis in advanced non‐small cell lung cancer
Authors: Jiang Wensheng , Cheng Huanqing , Yu Lili , Zhang Jie , Wang Yihui , Liang Yun , Lou Feng , Wang Huina , Cao Shanbo 
Published: November 2022

AbstractBackgroundTP53 mutations are frequent in non‐small cell lung cancer (NSCLC). Different categories of TP53 mutations may be associated with survival in advanced NSCLC, but their effect on prognosis is diverse. To date, a comprehensive comparison of the relationship between different classes of TP53 alterations and survival in advanced NSCLC has rarely been performed. Moreover, the prognostic significance of a novel approach called the evolutionary action of TP53 (EAp53) in advanced NSCLC is unclear.MethodsA total of 210 patients with NSCLC harboring TP53 mutation data were enrolled. Genomic and clinical data for the Memorial Sloan Kettering Cancer Center (MSKCC) cohort with advanced NSCLC were obtained from cBioPortal. Relationship between clinical characteristics and TP53 mutations was performed by Fisher's exact test or χ2 test. Overall survival (OS) analysis was evaluated using Kaplan–Meier method and Cox proportional hazards regression model.ResultsTP53 mutations were identified in 51.4% of NSCLC patients and were mainly located in exons 5, 7, and 8. The distribution patterns of missense and truncating mutations of TP53 were remarkably different. Among patients with advanced NSCLC who never received immune checkpoint inhibitor treatments, EAp53 high‐risk mutations were significantly associated with poor OS in both our cohort and the MSKCC cohort. Moreover, marked differences were observed in the mutational landscape between patients with EAp53 high‐risk mutations (HR group) and other patients (OT group). The HR group displayed higher mutation frequencies in the RTK, cell cycle, and DNA damage repair (DDR) pathways than the OT group. In addition, the tumor mutation burden in the HR group was significantly higher than that in the OT group.ConclusionsThis study provided important insights into the molecular‐clinical profile of TP53‐mutated NSCLC patients. Moreover, the data revealed that EAp53 high‐risk mutations were an independent prognostic factor for worse OS in advanced NSCLC.
Combined plasma C‐reactive protein, interleukin 6 and YKL‐40 for detection of cancer and prognosis in patients with serious nonspecific symptoms and signs of cancer
Authors: Videmark Alex N. , Christensen Ib J. , Feltoft Claus L. , Villadsen Mette , Borg Frederikke H. , Jørgensen Barbara M. , Bojesen Stig E. , Kistorp Caroline , Ugleholdt Randi , Johansen Julia S. 
Published: November 2022

AbstractBackground and methodsInflammation is a hallmark of cancer and its progression. Plasma levels of C‐reactive protein (CRP), interleukin‐6 (IL‐6) and YKL‐40 reflect inflammation, and are elevated in patients with cancer. This study investigated whether plasma CRP, IL‐6 and YKL‐40 had diagnostic value in 753 patients referred with nonspecific signs and symptoms of cancer to a diagnostic outpatient clinic.ResultsIn total, 111 patients were diagnosed with cancer within 3 months and 30 after 3 months. CRP, IL‐6 and YKL‐40 were elevated in 44%, 60% and 45% of the cancer patients, and in 15%, 33% and 25% of the patients without cancer. Elevated levels of all three markers were associated with risk of cancer within 3 months: CRP (odds ratio (OR) 4.41, 95% confidence interval (CI) 2.86–6.81), IL‐6 (OR = 2.89, 1.91–4.37) and YKL‐40 (OR = 2.42, 1.59–3.66). Multivariate explorative analyses showed that increasing values were associated with the risk of getting a cancer diagnosis (continuous scale: CRP (OR = 1.28, 1.12–1.47), carcinoembryonic antigen (CEA) (OR = 1.61, 1.41–1.98), CA19‐9 (OR = 1.15, 1.03–1.29), age (OR = 1.29, 1.02–1.63); dichotomized values: CRP (OR = 2.54, 1.39–4.66), CEA (OR = 4.22, 2.13–8.34), age (OR = 1.42, 1.13–1.80)). CRP had the highest diagnostic value (area under the curve = 0.69). Combined high CRP, IL‐6 and YKL‐40 was associated with short overall survival (HR = 3.8, 95% CI 2.5–5.9, p < 0.001).ConclusionIn conclusion, plasma CRP, IL‐6 and YKL‐40 alone or combined cannot be used to identify patients with cancer, but high levels were associated with poor prognosis. CRP may be useful to indicate whether further diagnostic evaluation is needed when patients present with nonspecific signs and symptoms of cancer.
About a rare association: Guillain–Barré Syndrome and polymyositis
Authors: Chabchoub Imen , Snoussi Mouna , Ammar Rania , Ben Salah Raida , Dammak Chifa , Frikha Faten , Bouaziz Mounir , Boudawara Tahia , Bahloul Zouhir 
Published: November 2022

AbstractGuillain–Barré syndrome (GBS) and polymyositis (PM) are two rare autoimmune diseases, one of which affects the peripheral nervous system and other the muscle. We report the case of a young woman with no previous medical history who was hospitalized with an ascending paralysis associated with acute respiratory failure due to a GBS. The patient was treated with plasmapheresis with unfavorable outcome and permanent proximal muscular disability. The diagnosis of an associated PM was retained based on biological myolysis and the results of electromyography and muscular biopsy. To our knowledge, this association of GBS and PM has been reported only once in the literature. The search for syndromic associations in the presence of an autoimmune helps to avoid diagnostic errors.
N‐Fluoroalkylated Morpholinos – a New Class of Nucleoside Analogues
Authors: Debreczeni Nóra , Hotzi Judit , Bege Miklós , Lovas Miklós , Mező Erika , Bereczki Ilona , Herczegh Pál , Kiss Loránd , Borbás Anikó 
Published: November 2022

AbstractThe first concise and efficient synthesis of some fluorine‐containing morpholino nucleosides has been developed. One synthetic strategy was based on the oxidative ring cleavage of the vicinal diol unit of uridine, cytidine adenosine and guanosine derivatives, followed by cyclisation of the dialdehyde intermediates by double reductive amination with fluorinated primary amines to obtain variousN‐fluoroalkylated morpholinos. Another approach involved cyclisation of the diformyl intermediates with ammonia source, followed by dithiocarbamate formation and desulfurization‐fluorination with diethylaminosulfur trifluoride yielding the corresponding morpholine‐based nucleoside analogues with aN‐CF3element in their structure.
Near‐Infrared Emissive Hypervalent Compounds with Germanium(IV)‐Fused Azobenzene π‐Conjugated Systems
Authors: Gon Masayuki , Yaegashi Misao , Tanaka Kazuo , Chujo Yoshiki 
Published: November 2022

AbstractA novel molecular design for showing near‐infrared (NIR) emission is still required for satisfying growing demands for NIR‐light technology. In this research, hypervalent compounds with germanium (Ge)‐fused azobenzene (GAz) scaffolds were discovered that can exhibit NIR emission (λPL=690∼721 nm, ΦPL=0.03∼0.04) despite compact π‐conjugated systems. The unique optical properties are derived from the trigonal bipyramidal geometry of the hypervalent compounds constructed by combination of Ge and azobenzene‐based tridentate ligands. Experimental and theoretical calculation results disclosed that the germanium‐nitrogen (Ge−N) coordination at the equatorial position strongly reduces the energy level of the LUMO (lowest unoccupied molecular orbital), and the three‐center four‐electron (3 c–4 e) bond in the apical position effectively rises the energy level of the HOMO (highest occupied molecular orbital). It is emphasized that large narrowing of the HOMO‐LUMO energy gap is achieved just by forming the hypervalent bond. In addition, the narrow‐energy‐gap property can be enhanced by extension of π‐conjugation. The obtained π‐conjugated polymer shows efficient NIR emission both in solution (λPL=770 nm and ΦPL=0.10) and film (λPL=807 nm and ΦPL=0.04). These results suggest that collaboration of a hypervalent bond and a π‐conjugated system is a novel and effective strategy for tuning electronic properties even in the NIR region.
CO2 Adsorption and Desorption for CO2 Enrichment at Low‐Concentrations Using Zeolite 13X
Authors: Bao Jie , Zhao Jigang , Bi Xiaotao Tony 
Published: November 2022

AbstractAdsorption of CO2 using zeolite 13X as adsorbent has been studied extensively, but little attention has been paid to CO2 adsorption at very low concentrations such as in the ambient air. Furthermore, there is almost no information on CO2 desorption characteristics. In a carbon enrichment for plant stimulation system, ambient CO2 is enriched from 400 to 1000 ppm to provide an enriched CO2 stream for plant growth in greenhouses. To provide essential design data, systematic performance tests were carried out to evaluate both the adsorption and desorption capacity, enrichment factor, moisture content, and cyclic performance. It was found that the adsorption capacity and CO2 concentration in the enriched air are a function of adsorption temperature and the difference of adsorption and desorption temperatures, for a given adsorbent loading at a properly selected gas flow rate.
A Review on Piezoelectric Materials and Their Applications
Authors: Sekhar Madunuri Chandra , Veena Eshwarappa , Kumar Nagasamudram Suresh , Naidu Kadiyala Chandra Babu , Mallikarjuna Allam , Basha Dudekula Baba 
Published: November 2022

AbstractPiezoelectric materials have the merits of fast response, speed, and high precision. These materials have been widely investigated for functional device applications such as sensors, actuators, microelectromechanical systems (MEMS), nanoelectromechanical systems (NEMS), 3D‐printing etc. This paper offers a review on recent advances in piezoelectric materials and their limitations. In addition, different piezoelectric materials such as lead‐based, lead‐free piezoelectric materials etc. are discussed, and their applications in the catalysis, energy harvesting, sensors, biomedical engineering, and additive manufacturing are addressed.
An empirical research of corporate social responsibility on creating the green brand equity: An exploratory of Vietnamese consumers' perception in the bank industry
Authors: Nguyen Thi Hong Nguyet , Tran Nguyen Khanh Hai , Do Khoa 
Published: November 2022

AbstractThis article examined and measured corporate social responsibility's (CSR) affection for green brand equity in the banking sector based on customer perception in the emerging market. The findings showed the importance of CSR in creating overall green brand equity through green brand association, green brand satisfaction, and green brand trust. The research results contribute significantly to expanding the corporate social responsibility theory. Moreover, managers can consider the research findings to develop strong green brand equity in customers' perception by promoting positive social responsibility activities and programs to increase interaction, satisfaction, and trust of customers towards green product brands. However, the research has several limitations, especially in geographical sampling size and sampling techniques.