bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extra-terrestrial influence on climate variability
Authors: Velichkova Ts P , Kilifarska N A 
Published: May 2022

Abstract
This study is focused on the analysis of signatures of extra-terrestrial influence on the centennial variability of some climatic variables, during the period 1900-2010. The applied lagged cross-correlation analysis shows evidence for a synchronisation between intensity of galactic cosmic rays (GCR) and two climate variables – the air surface temperature and the sea level pressure. The time delay of climatic response is not more than 5 years in the regions of stronger correlations. Moreover, the centennial variability of GCR is imprinted on the ozone mixing ratio at 70 hPa, suggesting its role of a mediator of GCR influence on climate. Having in mind the ozone’s capability to control the near tropopause temperature and humidity, we have suggested a mechanism describing the transmission of GCR signal from lower stratosphere, down to the Earth’s surface.
Impacts of large-scale refugee resettlement on LCLUC: Bidi Bidi refugee settlement, Uganda case study
Authors: Nakalembe Catherine , Zubkova Maria , Hall Joanne V , Argueta Fernanda , Giglio Louis 
Published: May 2022

Abstract
Uganda is the third-largest refugee-hosting country partly due to its open-door policy—deemed one of the most progressive. When new refugees arrive, refugee settlements are established rapidly, and irreversible changes to the landscape are inevitable. We utilize satellite data to map land cover (LC), land use, and burned area (BA) to assess their relationship in the context of large-scale refugee resettlement in Bidi Bidi—Uganda’s largest refugee settlement. We show inevitable dramatic changes in LC, e.g. built-up residential zones increased from 1.8% to 30%, while cropland increased from less than 0.7%–25.6% during our study period (2015–2019). In contrast, BA that affected more than 80% of the area was drastically reduced during the establishment phase (August–December 2017). Substantial reduction in BA was observed predominantly within the residential zones, but outside of the zones, BA was hardly affected by the arrival of refugees. Our study shows that these changes in LC and BA are mainly missing in the readily accessible satellite-derived data products, which impede assessment, planning, and implementation of humanitarian response programs. We discuss the importance of mapping at the appropriate spatial and temporal scales and the importance of context, sector, and geographic domain knowledge expertise in developing critical information products for informing programs to support vulnerable populations.
Study on flexural behavior of graphene oxide recycled concrete beams
Authors: Guo K , Yang Y Z , Zhou J H , Wu X Y 
Published: May 2022

Abstract
In order to study the flexural behavior of graphene oxide (GO) recycled concrete beams, 6 GO recycled concrete beams were studied, and observe its failure mode and process. The effects of GO content, oxygen content of GO and replacement rate of recycled aggregate on the flexural behavior of the test beams, including cracking load and ultimate load, concrete strain and steel strain, mid-span deflection, were analyzed. The test results show that the cracking load and ultimate load of recycled concrete beams with GO increase to a certain extent with the increase of GO content. And the higher the oxygen content of GO, the higher the ultimate bearing capacity of GO recycled concrete beams. With the increase of replacement rate of recycled aggregate, the cracking load and ultimate load of the test beams decrease.
The stone cantilevers rehabilitation of heritage buildings
Authors: Lapuste A V , Marton B 
Published: May 2022

Abstract
The aim of this article is to analyse multiple solutions for the stone cantilevers rehabilitation commonly found in heritage buildings. The stone cantilevers are arranged in the inner courtyards of historical buildings and ensure horizontal circulation. Throughout the article will analyse two categories of situations encountered in the rehabilitation practice: for the first situation the cantilever rehabilitation can be done after the stone plate demolition, and for the second situation the cantilever rehabilitation must be done without having the option of demolishing the flat plates. The difficulty of the intervention is given by the fact that the fixed ending restrain of the cantilever was ensured during the execution technology, the cantilever fixed in the masonry being ensured during the building of the wall. The rehabilitation of the stone cantilevers is conditioned by the fact that the fixed ending restrain point cannot be rebuild on the initial principles. This fact requires the adoption of rehabilitation principles based on a different approach to ensure the fixed end point. The proposed solutions solve both issues ensuring the required load capacity of the cantilever and ensuring the required level of fixed end restrain
Numerical studies regarding the behaviour a large span roof under seismic load when using anti-seismic devices
Authors: Mojolic C 
Published: May 2022

Abstract
The study presents the data obtained on a large span structure equipped with passive seismic isolators, placed at roof level, when subjected to multiple seismic loads. Three distinct passive isolation systems are taken into consideration to reduce the seismic response of the structure. The first case uses Friction Pendulum Systems (FP), the second uses a combination of High Damping Rubber Bearing (HDRB) and low friction pot-bearing systems, and the third implies the use of Lead Rubber Bearings (LRB) and low friction pot-bearing systems. Using seven sets of accelerograms, recorded and generated, the values for the main seismic response parameters are extracted in to underline the efficiency of the proposed systems. The results obtained in terms of natural vibration period, accelerations, bending moment, base shear are compared.
Flexible steel structures used for ski tunnels in Parang Mountains, Romania
Authors: Negrea D , Cazacu Ch 
Published: May 2022

Abstract
The main idea of this project was to create an access road for the tourists and also to improve the winter sports conditions, especially the ski, in the beautiful Parag Mountains. It was a very challenging project, as the road takes until 1600 m at alpine elevation. One of the structures was delivered and assembled in November 2019, in 3 weeks of hard weather conditions, with a 5 working men team.
Cement replacement by used paints in plasters mortars mixtures
Authors: Siomin AC , Tintisan ML , Zaharie A , Manea DL 
Published: May 2022

Abstract
This research started from the fact that humanity exploits on an industrial scale and chaotically consumes the raw materials that this planet offers, without realizing the importance of reusing waste and the possibility of introducing them in the production of plaster mortars. Thus, an attempt is made to create a balance between raw materials and the exploitation of new resources, so that future generations can have access to raw materials. Plaster mortar mixtures were made by using waste from construction sites, respectively certain percentages of the amount of cement were replaced with used paints. In order to reduce the costs of transporting and transferring waste to the landfill, most of the executors (builders) at the stage of systematization of the land, bury all the waste, not respecting the conditions given by the environmental agreement. Through a waste management, construction materials are recovered, in this case used paint and reused in the preparation of plaster mortar. Starting from a plaster mortar mixture, the cement was replaced in a percentage of 10% and 15% with used paint, resulting in significantly higher bending strengths. We must be responsible and contribute to the protection of the environment by recycling/reusing waste from construction materials.
Optimization method based on genetic algorithm for the mass compensation of the rotor on-line dynamic balance system
Authors: Song Q L , Wang Z , Liang L 
Published: May 2022

Abstract
The rotor is the key component of the rotary drilling rig, it can realize the rotation and feed movement of the drill. the rotor unit of the rotary drilling rig should take on-line dynamic. Because unbalanced faults would lead to vibration. In order to further improve the pricision of on-line dynamic balance, an optimization strategy based on Genetic Algorithm for the mass compensation of the rotor on-line dynamic balancing system is proposed. A mass compensation optimization model is established. By the way of taking the phase of counterweight movement as the optimization variable. At the same time,taking the residual stress under dynamic balance as the optimization objective. According to the principle of Genetic Algorithm, the movement phase of the counterweight can be calculated when the residual force reaches the minimum value. By performing simulation analysis, the residual force can be calculated under different rotating speeds and different amount of unbalance, the residual force after optimizing balance can be reduced greatly. The simulation results showed that the residual force of the rotor after optimizing balance can decrease by 95.74% on average. Therefore, an optimization strategy based on Genetic Algorithm for the mass compensation of the rotor can effectively improve dynamic balance precision and operating performance of rotary drilling rig.
The analysis of TBM cutter stress under different construction environment
Authors: Wang Z N , Wang Q Y , Hu B B , Wei C , Wu Q N 
Published: May 2022

Abstract
As the country’s underground tunnels continue to expand, underground construction technology has been developed rapidly. In order to meet the development needs of construction technology in China, Tunnel Boring Machine (TBM) has made great progress due to its own advantages. In this paper, feed amount of disc cutter on rock crushing under complex working conditions is considered. The mechanism of rock fragmentation is analyzed. The force between disc cutter and the rock is studied. The accuracy of the model is verified by setting up a TBM rock fragmentation experiment platform. This study provides technical support for TBM construction parameters under different working conditions.
A Systematic Review and Meta-analysis of Face-to-face Medication Adherence Interventions for Patients with Long Term Health Conditions
Authors: Akhter Kalsoom , Sutton Stephen , Mirzaei Venus , Kassavou Aikaterini 
Published: May 2022

Abstract

Background
Although previous reviews demonstrated effectiveness related to medication adherence interventions, they incorporated various digital platforms and other multiple delivery modes, which makes difficult to distinguish what aspects of the interventions led to effectiveness.

Purpose
This review aimed to (i) estimate the efficacy of face-to-face medication adherence interventions on adherence outcomes, in adults with Long Term Health Conditions (LTHCs) and (ii) identify the Behaviour Change Techniques (BCTs) used in the interventions and examine their potential impact on efficacy.

Methods
Cochrane Controlled Register of Trials, Embase, MEDLINE (Ovid), PsycINFO, Web of Science, PubMed, and Scopus databases were searched. Randomized controlled trials were included if they described an intervention to improve medication adherence, delivered via face-to-face only, and included patients with LTHCs. Studies were excluded if they used additional delivery modes, involved family members or used a group format. In addition, use of BCTs was coded.

Results
20 studies were included (n = 3667). Statistically significant pooled effects were found favoring the intervention than control, for the following MEMS (electronic monitoring) measures: percentage of prescribed doses taken on time over a period of 3 weeks to 2 months (MD 9.34, 95% CI 4.36–14.33, p = .0002; I2 =0%); percentage of prescribed doses taken for a period of 1 week to 2 months (MD 5.63, 95% CI 1.62–9.64, p = .006; I2 = 51%) and for 1 month (OR = 2.51, 95% CI 1.37–4.57, p = .003; I2 = 0%); percentage of days correct doses taken for 1 month to 14 weeks (MD 6.59, 95% CI 0.74–13.15, p = .03; I2 = 68%). Studies using the Morisky scale showed a significant between group difference for 1–3 months (MD 0.86, 95% CI 0.59–1.13, p &lt; .00001; I2 = 0%). Overall, more BCTs were identified in intervention conditions than in comparison conditions (22 vs. 10). The impact of BCTs on intervention effectiveness could not be established as the analyses were underpowered.

Conclusions
Face-to-face interventions increased adherence to medication among adult patients with LTHCs. Although we were able to identify BCTs among interventions, data were insufficient to determine the impact of particular BCTs on intervention effectiveness.
Somatic Symptom Disorder in Elderly Patients With Essential Hypertension in Community Hospital
Authors: Chen Bing-xu , Liao Jia-yu , Fu Yun-fei , Qin Shou-min , Jiang Meng , Mao Jia-liang , Bu Jun 
Published: May 2022

Abstract

Background
To investigate and analyze the prevalence of somatic symptom disorder in elderly patients with essential hypertension in community hospitals.

Methods
A total of 5,473 patients in 100 community hospitals in Shanghai from January to June 2019 were enrolled in the cross-sectional study. Among them, 3,080 patients were diagnosed with essential hypertension and 2,393 patients without essential hypertension. The corresponding clinical data were collected and the somatic symptom self-rating scale was used to evaluate these patients.

Results
The prevalence of somatic symptom disorder in elderly patients with essential hypertension was higher than those without essential hypertension (45.3% vs. 31.8%, P &lt; 0.01), and the score of somatic symptom self-rating scale was higher than patients without essential hypertension (34.3 ± 8.5 vs. 32.9 ± 8.1, P &lt; 0.01). In elderly patients with essential hypertension, concentration difficulties (72.5% vs. 69.6%, P = 0.021), fatigue (65.6% vs. 60.2%, P &lt; 0.01), dizziness and headache (62.6% vs. 53.3%, P &lt; 0.01), and other somatic symptoms were higher than patients without essential hypertension.

Conclusions
The prevalence and severity of somatic symptom disorder in elderly patients with essential hypertension are higher than those without essential hypertension.
Evaluating Bilingual Children’s Native Language Abilities in Côte d’Ivoire: Introducing the Ivorian Children’s Language Assessment Toolkit for Attié, Abidji, and Baoulé
Authors: Jasińska Kaja , Akpe Yapo Hermann , Seri Blahoua Axel Debaye , Zinszer Benjamin , Agui-Kouadio Rodrigue Yoffo , Mulford Kelsey , Curran Erin , Ball Mary-Claire , Tanoh Fabrice 
Published: May 2022

AbstractFew standardized language assessments are adapted to different cultural and linguistic contexts to assess children’s first language (L1) abilities. We introduce the Ivorian Children’s Language Assessment Toolkit for measuring phonological awareness, vocabulary, oral comprehension, and tone awareness in the Abidji, Attié, and Baoulé languages of Côte d’Ivoire. Six hundred and three primary-school children (age 4–14) completed language assessments in their L1 and French. The toolkit provided a reliable and comprehensive assessment of children’s language abilities. We observed age- and grade-related increases in all subtest scores. Still, children scored higher in their L1 compared to French, highlighting the need for language assessments in a bilingual’s two languages to achieve an accurate measure of children’s language abilities. The ability to benchmark children’s scores relative to age- and grade-norms are discussed in the context of language of instruction education policies as well as the potential use of age- and grade-norms in identifying children with language impairment and/or children who are at risk for reading difficulties due to poor language skills.
Three-nucleotide periodicity of nucleotide diversity in a population enables the identification of open reading frames
Authors: Jiang Mengyun , Ning Weidong , Wu Shishi , Wang Xingwei , Zhu Kun , Li Aomei , Li Yongyao , Cheng Shifeng , Song Bo 
Published: May 2022

Abstract
Accurate prediction of open reading frames (ORFs) is important for studying and using genome sequences. Ribosomes move along mRNA strands with a step of three nucleotides and datasets carrying this information can be used to predict ORFs. The ribosome-protected footprints (RPFs) feature a significant 3-nt periodicity on mRNAs and are powerful in predicting translating ORFs, including small ORFs (sORFs), but the application of RPFs is limited because they are too short to be accurately mapped in complex genomes. In this study, we found a significant 3-nt periodicity in the datasets of populational genomic variants in coding sequences, in which the nucleotide diversity increases every three nucleotides. We suggest that this feature can be used to predict ORFs and develop the Python package ‘OrfPP’, which recovers ~83% of the annotated ORFs in the tested genomes on average, independent of the population sizes and the complexity of the genomes. The novel ORFs, including sORFs, identified from single-nucleotide polymorphisms are supported by protein mass spectrometry evidence comparable to that of the annotated ORFs. The application of OrfPP to tetraploid cotton and hexaploid wheat genomes successfully identified 76.17% and 87.43% of the annotated ORFs in the genomes, respectively, as well as 4704 sORFs, including 1182 upstream and 2110 downstream ORFs in cotton and 5025 sORFs, including 232 upstream and 234 downstream ORFs in wheat. Overall, we propose an alternative and supplementary approach for ORF prediction that can extend the studies of sORFs to more complex genomes.
Pollock: fishing for cell states
Authors: Storrs Erik P , Zhou Daniel Cui , Wendl Michael C , Wyczalkowski Matthew A , Karpova Alla , Wang Liang-Bo , Li Yize , Southard-Smith Austin , Jayasinghe Reyka G , Yao Lijun , Liu Ruiyang , Wu Yige , Terekhanova Nadezhda V , Zhu Houxiang , Herndon John M , Puram Sid , Chen Feng , Gillanders William E , Fields Ryan C , Ding Li 
Published: May 2022

AbstractMotivationThe use of single-cell methods is expanding at an ever-increasing rate. While there are established algorithms that address cell classification, they are limited in terms of cross platform compatibility, reliance on the availability of a reference dataset and classification interpretability. Here, we introduce Pollock, a suite of algorithms for cell type identification that is compatible with popular single-cell methods and analysis platforms, provides a set of pretrained human cancer reference models, and reports interpretability scores that identify the genes that drive cell type classifications.ResultsPollock performs comparably to existing classification methods, while offering easily deployable pretrained classification models across a wide variety of tissue and data types. Additionally, it demonstrates utility in immune pan-cancer analysis.Availability and implementationSource code and documentation are available at https://github.com/ding-lab/pollock. Pretrained models and datasets are available for download at https://zenodo.org/record/5895221.Supplementary informationSupplementary data are available at Bioinformatics Advances online.
InterPepScore: a deep learning score for improving the FlexPepDock refinement protocol
Authors: Johansson-Åkhe Isak , Wallner Björn 
Published: May 2022

AbstractMotivationInteractions between peptide fragments and protein receptors are vital to cell function yet difficult to experimentally determine in structural details of. As such, many computational methods have been developed to aid in peptide–protein docking or structure prediction. One such method is Rosetta FlexPepDock which consistently refines coarse peptide–protein models into sub-Ångström precision using Monte-Carlo simulations and statistical potentials. Deep learning has recently seen increased use in protein structure prediction, with graph neural networks used for protein model quality assessment.ResultsHere, we introduce a graph neural network, InterPepScore, as an additional scoring term to complement and improve the Rosetta FlexPepDock refinement protocol. InterPepScore is trained on simulation trajectories from FlexPepDock refinement starting from thousands of peptide–protein complexes generated by a wide variety of docking schemes. The addition of InterPepScore into the refinement protocol consistently improves the quality of models created, and on an independent benchmark on 109 peptide–protein complexes its inclusion results in an increase in the number of complexes for which the top-scoring model had a DockQ-score of 0.49 (Medium quality) or better from 14.8% to 26.1%.Availability and implementationInterPepScore is available online at http://wallnerlab.org/InterPepScore.Supplementary informationSupplementary data are available at Bioinformatics online.
The Long Arm Of Welfare Retrenchment: How New Right Socio-Economic Policies In The 1980s Affected Contact With The Criminal Justice System In Adulthood
Authors: Gray Emily , Farrall Stephen , Mike Jones Phil 
Published: May 2022

Abstract
The socio-economic policies of the British ‘New Right’ administrations have been associated with increases in crime using aggregate data. This paper assesses if the trend remains when we test individual-level relationships using two British cohort studies (the National Child Development Study 1958 and the British Cohort Study 1970). Our results point to a set of long-term ‘period effects’ in which those reliant on the welfare state at specific time-points in the 1980 and 1990s (regardless of their age) were more likely to be drawn into the criminal justice system in adulthood (circa 2000). This paper considers (i) how British ‘New Right’ welfare policies may have had unintended, but lasting consequences for individuals in receipt of social security assistance and (ii) the interplay between micro and macro criminological analysis.
Single unit analysis and wide-field imaging reveal alterations in excitatory and inhibitory neurons in glioma
Authors: Gill Brian J A , Khan Farhan A , Goldberg Alexander R , Merricks Edward M , Wu Xiaoping , Sosunov Alexander A , Sudhakar Tejaswi D , Dovas Athanassios , Lado Wudu , Michalak Andrew J , Teoh Jia Jie , Liou Jyun-you , Frankel Wayne N , McKhann Guy M , Canoll Peter , Schevon Catherine A 
Published: May 2022

Abstract
While several studies have attributed the development of tumour-associated seizures to an excitatory-inhibitory imbalance, we have yet to resolve the spatiotemporal interplay between different types of neuron in glioma-infiltrated cortex.
Herein, we combined methods for single unit analysis of microelectrode array recordings with wide-field optical mapping of Thy1-GCaMP pyramidal cells in an ex vivo acute slice model of diffusely infiltrating glioma. This enabled simultaneous tracking of individual neurons from both excitatory and inhibitory populations throughout seizure-like events. Moreover, our approach allowed for observation of how the crosstalk between these neurons varied spatially, as we recorded across an extended region of glioma-infiltrated cortex.
In tumour-bearing slices, we observed marked alterations in single units classified as putative fast-spiking interneurons, including reduced firing, activity concentrated within excitatory bursts and deficits in local inhibition. These results were correlated with increases in overall excitability. Mechanistic perturbation of this system with the mTOR inhibitor AZD8055 revealed increased firing of putative fast-spiking interneurons and restoration of local inhibition, with concomitant decreases in overall excitability.
Altogether, our findings suggest that diffusely infiltrating glioma affect the interplay between excitatory and inhibitory neuronal populations in a reversible manner, highlighting a prominent role for functional mechanisms linked to mTOR activation.