bluuebunny/crossref_metadata_2025_split huggingface dataset:
Supporting Sonic Interaction in Creative, Shared Virtual Environments
Authors: Men Liang , Bryan-Kinns Nick 
Published: October 2022

AbstractThis chapter examines user experience design for collaborative music making in shared virtual environments (SVEs). Whilst SVEs have been extensively researched for many application domains including education, entertainment, work and training, there is limited research on the creative aspects. This results in many unanswered design questions such as how to design the user experience without being detrimental to the creative output, and how to design spatial configurations to support both individual creativity and collaboration. Here, we explore multi-modal approaches to supporting creativity in collaborative music making in SVEs. We outline an SVE, LeMo, which allows two people to create music collaboratively. We then present two studies; the first explores how free-form visual 3D annotations instead of spoken communication can support collaborative composition processes and human–human interaction. Five classes of use of annotation were identified in the study, three of which are particularly relevant to the future design of sonic interactions in virtual environments. The second study used a modified version of LeMo to test the support for a creative collaboration of two different spatial audio settings, which according to the results, changed participants’ behaviour and affected their collaboration. Finally, design implications for the auditory design of SVEs focusing on supporting creative collaboration are given.
Trustworthiness and Well-Being: The Ethical, Legal, and Social Challenge of Robotic Assistance
Authors: Beetz Michael , Engel Uwe , Hoyer Nina , Kähler Lorenz , Langer Hagen , Schultheis Holger , Straube Sirko 
Published: October 2022

AbstractIf a technology lacks social acceptance, it cannot realize dissemination into society. The chapter thus illuminates the ethical, legal, and social implications of robotic assistance in care and daily life. It outlines a conceptual framework and identifies patterns of trust in human–robot interaction. The analysis relates trust in robotic assistance and its anticipated use to open-mindedness toward technical innovation and reports evidence that this self-image unfolds its psychological impact on accepting robotic assistance through the imagined well-being that scenarios of future human–robot interaction evoke in people today. All findings come from the population survey of the Bremen AI Delphi study.
Artificial Intelligence and the Labor Market: Expected Development and Ethical Concerns in the German and European Context
Authors: Engel Uwe , Dahlhaus Lena 
Published: October 2022

AbstractThe chapter examines the question of whether people must fear for their jobs due to artificial intelligence (AI). A “competitive scenario” with a design to test for this appeared in the Delphi survey. The chapter shows how realistic this scenario is and its sociological implications, with a basis in expert opinions. In addition, the chapter sheds light on how much people see AI affecting themselves in their jobs, their future standard of living, and quality of life. The results in these respects paint a much more positive picture than the public discussion of AI leads us to expect. The chapter deals with ethical concerns that AI could lead to discrimination in the labor market and the perceived need for public policy interventions to ensure that AI develops ethically. An aggregate data analysis reveals substantial variations across EU countries and significant correlations with a country’s prosperity, risk of poverty, multi-ethnicity, and inherent trust in institutions and fellow men. We examine the odds of such concerns in Germany, as a function of socio-structural variables.
The Bremen AI Delphi Study
Authors: Engel Uwe , Dahlhaus Lena 
Published: October 2022

AbstractThe chapter introduces the Bremen AI Delphi study, recently conducted in Germany’s city-state of Bremen. This study consists of a large Delphi survey of scientists from different backgrounds and involves a subsample of stakeholders from politics (N = 297 participants). The study consists also of a closely related population survey (N = 216 participants). The chapter describes sampling and survey design and introduces basic features of questionnaire architecture.
The Challenge of Autonomy: What We Can Learn from Research on Robots Designed for Harsh Environments
Authors: Straube Sirko , Hoyer Nina , Will Niels , Kirchner Frank 
Published: October 2022

AbstractIn addition to areas of application in people’s everyday lives and the area of education and services, robots are primarily envisioned in non-immediate living environments by the society—i.e., in inaccessible or even hostile environments to humans. The results of this population survey clearly demonstrate that such application options come across with a high level of acceptance and application potential among the population. Nevertheless, it is expected that the underlying AI in such systems works reliably and that safety for humans is guaranteed.In this chapter, the results of the study are compared with state-of-the-art systems from classical application environments for robots, like the deep-sea and space. Here, systems have to interact with their environment to a large extent on their own over longer periods of time. Although typically the designs are such that humans are able to intervene in specific situations and so external decisions are possible, the requirements for autonomy are also extremely high. From this perspective one can easily derive what kind of requirements are also necessary, and what challenges are still in front of us, when robots should be acting largely autonomous in our everyday life.
Engaging Stakeholders by Implementing RRI in the Social Lab Process – A Single Case Study
Authors: Frankus Elisabeth , Hönigmayer Helmut 
Published: October 2022

AbstractWith new and emerging technologies, process of Research and Innovation (R & I) changed. Some point out an “increasingly growing complexity” (Gianni 2020: 14) that needs to be addressed. Other scholars note that “the pace of technological change has increased dramatically” (Gould 2012: 2) This complexity requires new modes of engaging stakeholders to the R & I process. As mentioned in Chap. 1 of this book, the concept of Responsible Research and Innovation (RRI) (von Schomberg 2013) was created as a way to better engage stakeholders and their needs.
Public Engagement in the Tradition of Participatory Approaches – An Approximation
Authors: Warnke Philine , Bratan Tanja , Wunderle Ulrike 
Published: October 2022

AbstractPublic engagement is viewed as a prominent aspect of responsible research and innovation (RRI) both in academia and policy circles. In our paper, we would like to contribute to refining the notion of public participation as an RRI element by assessing the potential of four domains of participatory R & I theory and practices that have to date received little recognition in the RRI context: 1. Participatory design, 2. user-led innovation, 3. participatory research and 4. systemic R & I policy instruments. We test the usefulness of our concepts with a set of case studies from a recent RRI research project.
Zugänge zur Teilhabeforschung mit Menschen mit Komplexer Behinderung: Methodologische und methodische Überlegungen zur Beteiligung eines nicht berücksichtigten Personenkreises
Authors: Keeley Caren 
Published: October 2022

ZusammenfassungDer Beitrag befasst sich mit methodischen und methodologischen Überlegungen zur Forschung mit Menschen mit Komplexer Behinderung. Unter Bezugnahme auf das Forschungsprojekt Teilsein & Teilhaben wird insbesondere der Frage nachgegangen, wie teilhabeorientierte Forschung mit Menschen mit Komplexer Behinderung gestaltet werden kann. Die zentrale Erkenntnis lautet, dass sich der Ausschluss des Personenkreises aus der Teilhabeforschung nur verhindern lässt, wenn Teilhabe im und am Forschungsgeschehen von allen Beteiligten in achtsamer Weise gestaltet wird. Der Beitrag schließt mit den sich daraus ergebenden methodologischen Konsequenzen.
Mehr Teilhabe durch partizipative Forschung: Grundzüge eines Forschungsstils
Authors: von Unger Hella 
Published: October 2022

ZusammenfassungPartizipative Forschung rückt das Konzept der Teilhabe in und durch Forschung ins Zentrum. Ziel ist es, die gesellschaftliche Teilhabe benachteiligter Gruppen zu stärken – und zwar durch deren Beteiligung an Forschungsprozessen. Drei Komponenten zeichnen den Ansatz aus: a) die doppelte Zielsetzung, Wirklichkeit zu verstehen und zu verändern, b) die Beteiligung von Co-Forschenden mit Entscheidungsmacht und c) Befähigungs-, Reflexions- und Ermächtigungsprozesse. Ausgewählte Herausforderungen, wie ungleiche Voraussetzungen für Partizipation, werden besprochen.
Teilhabe – Versuch einer Begriffsbestimmung
Authors: Bartelheimer Peter , Behrisch Birgit , Daßler Henning , Dobslaw Gudrun , Henke Jutta , Schäfers Markus 
Published: October 2022

ZusammenfassungDer Teilhabebegriff findet seine Verwendung in sehr unterschiedlichen sozialpolitischen Diskursen mit ihren je spezifischen Ausrichtungen. Diese unterschiedlichen Bedeutungszusammenhänge des Teilhabebegriffs werden herausgearbeitet und zentrale Aspekte des Bedeutungskerns in Abgrenzung zu verwandten Begriffen wie Partizipation, Inklusion oder Integration identifiziert.
Zugänge zur selbstbestimmten Teilhabe in der stationären Altenhilfe. Ein sequentielles Mixed-Methods-Design zur Identifizierung teilhabefördernder und -hemmender Faktoren
Authors: Conen Ina , Schultz Laura , Bleck Christian , Henke Stefanie 
Published: October 2022

ZusammenfassungDie in diesem Beitrag vorgestellte empirische Studie untersucht mit einem sequentiellen Mixed Methods-Design Bedingungen der Gewährleistung von Teilhabe von Bewohner*innen stationärer Altenpflegeeinrichtungen. Insbesondere widmet sich der Beitragzum einenden methodischen Verfahren, die geeignet sind, die Praxis von Teilhabeförderung multiperspektivisch zu erkunden sowie kognitiv eingeschränkte Menschen einzubeziehen.Zum anderenbeleuchtet er den Transfer der Ergebnisse in ein Musterrahmenkonzept, welches Einrichtungen zur Umsetzung von Teilhabeförderung dienen soll.
Ältere Menschen, die als „geistig behindert“ kategorisiert sind, und ihr Blick auf subtile Machtprozesse
Authors: Stadel Wolfgang 
Published: October 2022

ZusammenfassungIm Sinne einer Enthinderungshilfe müssen subjektive Vorstellungen der Adressat*innen für die Soziale Arbeit Ausgangspunkt für helfendes Handeln sein. Menschen, die als geistig behindert kategorisiert sind und lange den Hilfesystemen zugehörig sind oder waren, berichten alsExpert*innen der Sache.Ein figurationssensibles Verständnis ermöglicht den Blick auf subtile Machtbalancen und verdeutlicht den Bedarf an unterstützten Aushandlungsprozessen.
Analysis of a Stabilised Finite Element Method for Power-Law Fluids
Authors: Barrenechea Gabriel R. , Süli Endre 
Published: October 2022

AbstractA low-order finite element method is constructed and analysed for an incompressible non-Newtonian flow problem with power-law rheology. The method is based on a continuous piecewise linear approximation of the velocity field and piecewise constant approximation of the pressure. Stabilisation, in the form of pressure jumps, is added to the formulation to compensate for the failure of the inf-sup condition, and using an appropriate lifting of the pressure jumps a divergence-free approximation to the velocity field is built and included in the discretisation of the convection term. This construction allows us to prove the convergence of the resulting finite element method for the entire range $$r>\frac{2 d}{d+2}$$

r
>

2
d

d
+
2

of the power-law index r for which weak solutions to the model are known to exist in d space dimensions, $$d \in \{2,3\}$$

d
∈
{
2
,
3
}

.
Operational planning of distributed energy generation for a semiconductor fabrication plant
Authors: Poemsl Tobias F. , Siddiqui Afzal S. 
Published: October 2022

AbstractThe semiconductor industry is well known for its high resource consumption due to its clean room usage and power-intensive manufacturing technology. This is a significant financial burden for semiconductor fabrication plant owners who wish to minimize the cost needed to cover the electricity and gas loads for their daily operations. From a historical perspective, those electricity and gas cost reductions have been enabled by more energy-efficient manufacturing technologies. Due to the complexity of factors influencing the energy system of a semiconductor plant, other aspects have often been neglected and also not been studied intensively in the academic literature so far. One possibility for reducing energy costs is the integration of a microgrid as on-site distributed energy resources (DER) may offer a less cost-intensive way to supply the energy needed. Therefore, this paper seeks to answer the following research question: How much expected cost can be saved and risk mitigated at a semiconductor fabrication plant via DER? More precisely, in this paper, a microgrid at a semiconductor fabrication plant that has installed DER with combined heat and power (CHP) applications and demand response (DR) is used to simulate the expected annual energy costs under given uncertain electricity and gas prices at different installed capacity levels. A simulation-based approach is used to evaluate several DER capacity sizes. The results of the simulation show that installations of DER at a semiconductor microgrid can dominate the base case of doing nothing, considering the expected minimized cost, the expected CO2 emissions, and conditional value-at-risk (CVaR). In fact, DER can reduce the expected annual energy bill by up to 6%, whereas annual expected CO2 emissions can even be reduced by up to 22%. Moreover, with DER, a microgrid’s risk is reduced as it can react to market conditions and local demand. Additionally, the true potential of microgrid cost savings can only be enabled when DR is allowed and proves particularly effective when energy prices are more volatile.
“You really need a whole community”: a qualitative study of mothers’ need for and experiences with childcare support during cancer treatment and recovery
Authors: Pritlove Cheryl , Dias Lisa V. 
Published: October 2022

AbstractPurposeA cancer diagnosis poses unique challenges for moms with young children who must balance illness-management alongside existing paid (e.g., employment) and unpaid (e.g., domestic/caregiving) work. The goal of this study was to improve understanding of the support needs of mothers living with cancer and their experiences receiving psychosocial and childcare support from a community organization, the Nanny Angel Network (NAN).MethodsMothers who accessed NAN services during their cancer treatment and/or recovery (N = 20) participated in qualitative semi-structured interviews. Thematic analysis was used to inductively and deductively identify emerging patterns in the data and theoretical abduction was applied to further interpret participants’ accounts using a feminist political economy framework.ResultsParticipants expressed how balancing the demands of patienthood and parenthood was challenging and how cancer treatment created new needs for support with care work. Mothers explained that NAN offered indispensable family-centered support largely missing from the health care system, promoting improved physical, psychosocial, and relational health for them and their families. While accessible from a cost-perspective, participants identified different pathways, including awareness, cross-system collaboration, and stable funding, that limited timely access to NAN.ConclusionAccess to family-centered care, such as that offered through NAN, was vital to the health and healing of the study participants and their families. Improved collaboration with and investment in community organizations like NAN that have a strong infrastructure to support moms living with cancer offers a practical, feasible, and immediate solution to help address some of the distinct challenges this population faces.
ZD6474 attenuates TGF-β1-induced fibrosis in human Tenon fibroblasts and inhibits neovascularization via AKT-mTOR signaling pathway
Authors: Liu Wenting , Chen Yaying , Song Xiangyuan , Xue Yiwen , Zhang Yuyan 
Published: October 2022

Abstract
Purpose
To investigate the anti-fibrotic effect of ZD6474 (a novel inhibitor of VEGF and EGF) in TGF-β1 stimulated human Tenon’s capsule fibroblasts (HTFs) and the anti-angiogenetic role in HUVECs, compared to that of mitomycin C (MMC).

Methods
The effects of ZD6474 on cell proliferation or migration in TGF-β1-stimulated HTFs and HUVECs were determined, using CCK8 or wound healing assay, respectively. The typical markers of fibrosis in TGF-β1-stimuated HTFs were detected, vimentin by immunofluorescence, α-SMA and snail by western blot. Tube formation was applied to validate the anti-angiogenesis effect in HUVECs following ZD6474 treatment. Furthermore, phosphorylated AKT and mTOR (p-AKT and p-mTOR) were evaluated, compared to the standardized total AKT and mTOR, using western blot.

Results
There was almost no decreased cell viability in HTFs following ZD6474 (≤ 1 μM/mL) treatment, but MMC (> 50 μg/mL) significantly impaired cell viability. ZD6474 significantly inhibited TGF-β1-stimulated proliferation and migration in HTFs, compared to control group (**P < 0.01). ZD6474 also significantly attenuated the TGF-β1-stimulated expression of vimentin, α-SMA and snail in HTFs. Tube formation was notably interrupted in HUVECs following ZD6474 treatment (**P < 0.01). P-AKT and p-mTOR were significantly decreased in response to ZD6474 treatment in TGF-β1- induced HTFs and HUVECs.

Conclusions
ZD6474 exerts anti-proliferation and anti-fibrotic effects in TGF-β1-stimulated HTFs perhaps via regulating AKT-mTOR signaling pathway. ZD6474 also inhibited proliferation, migration and tube formation in HUVECs via the same signaling pathway. We concluded that ZD6474 may be potentially a novel agent in preventing bleb dysfunction following glaucoma filtration surgery (GFS).
Role of Melatonin in the Management of Sleep and Circadian Disorders in the Context of Psychiatric Illness
Authors: Moon Eunsoo , Kim Kyungwon , Partonen Timo , Linnaranta Outi 
Published: October 2022

Abstract
Purpose of Review
We present a review of research on the role of melatonin in the management of sleep and circadian disorders, stressing current overall view of the knowledge across psychiatric disorders.

Recent Findings
Dysregulation of sleep and circadian rhythms has been established in several psychiatric and neurocognitive disorders for long. Recent research confirms this finding consistently across disorders. The secretion of melatonin in schizophrenia and neurocognitive disorders is reduced due to a smaller volume and enlarged calcification of the pineal gland. On the other hand, melatonin dysregulation in bipolar disorder may be more dynamic and caused by light-sensitive melatonin suppression and delayed melatonin secretion. In both cases, exogenous melatonin seems indicated to correct the dysfunction. However, a very limited number of well-designed trials with melatonin to correct sleep and circadian rhythms exist in psychiatric disorders, and the evidence for efficacy is robust only in autism, attention deficit hyperactivity disorder (ADHD), and neurocognitive disorders. This topic has mainly not been of interest for recent work and well-designed trials with objective circadian parameters are few. Overall, recent studies in psychiatric disorders reported that melatonin can be effective in improving sleep parameters such as sleep onset latency, sleep efficiency, and sleep quality. Recent meta-analysis suggests that optimal dosage and dosing time might be important to maximize the efficacy of melatonin. The knowledge base is sufficient to propose well-designed, larger trials with circadian parameters as inclusion and outcome criteria. Based on the partly fragmentary information, we propose testing efficacy in disorders with neurocognitive etiopathology with later and higher dosing, and affective and anxiety disorders with lower and earlier dosing of melatonin.

Summary
Melatonin is promising for the correction of sleep and circadian abnormalities in psychiatric disorders. However, research results on its effect are still few and need to be accumulated. For effective use of melatonin, it is necessary to consider the appropriate dosage and administration time, depending on the individual abnormality of sleep and circadian rhythms.
Chemical characterization and biological activities of ulvan extracted from Ulva fasciata (Chlorophyta)
Authors: Barakat Khouloud M. , Ismail Mona M. , Abou El Hassayeb Hala E. , El Sersy Nermeen A. , Elshobary Mostafa E. 
Published: October 2022

AbstractUlvan is a sulfated heteropolysaccharide present in the cell wall of Ulva species with a unique structure and biological potential used in various fields. Chemical characterization was carried out to determine the structure of ulvan from Ulva fasciata Delile collected from Eastern Harbor, Alexandria coast, Egypt. Ulva contains 31.5% carbohydrate with a total ulvan content of 43.66% of total carbohydrate (13.75 g/100 g DW) and sulfate content of 20.45% of ulvan. FTIR spectrum presented signals of the sulfate ester (C–O–S) and sulfate groups (S=O), typical for ulvan. GC–MS revealed that ulvan was mainly composed of rhamnose and fucose. 1H-NMR spectra of ulvan showed identical behavior of monosaccharides nature with peaks characteristic of sulfated polysaccharides at 3.2–5.3 ppm region. Scanning electron micrographs (SEM) demonstrated amorphous architecture, and the sulfated nature of polysaccharides was emphasized by EDX analysis. The extracted ulvan showed significant antimicrobial activity against human and fish pathogens as well as antifouling bacteria with minimum inhibitory concentrations (MIC) of 8 µg/mL. The extracted ulvan exhibited potent antioxidant activity with a scavenging effect of 84.93% for 2,2-diphenyl-1-picrylhydrazy free radical (DPPH). Moreover, it showed anti-arthritic properties for the first time with a maximum inhibition of 86.04% with IC50 of 43.21%, indicating their potential value for the health and food industry.
Eurypterids from the Price Formation of Virginia: First Eurypterids from the Mississippian of North America
Authors: Plotnick Roy E. , Lamsdell James C. 
Published: October 2022

AbstractA new hibbertopterid eurypterid,Cyrtoctenus bambachin. sp., is described from the Early Mississippian (Tournaisian) Price Formation of western Virginia. The same unit yields an unidentifiable stylonurine eurypterid. These are the first eurypterids documented from the Mississippian of North America, and only the fourth locality of this age anywhere in the world to yield eurypterids.UUID:http://zoobank.org/5c84d3a2-ea5a-402c-970d-9b0d867f52c7