bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does Cr(CO)3Really behave as Catalyst in the Diels‐Alder Reaction of Styrene with Cyclopentadiene? A Molecular Electron Density Theory Study
Authors: Domingo Luis R. , Aurell María José , Ríos‐Gutiérrez Mar 
Published: June 2022

AbstractThe role of the coordination of the Cr(CO)3complex to the aromatic ring of styrene in the Diels‐Alder (DA) reaction towards cyclopentadiene (Cp) has been studied within the Molecular Electron Density Theory (MEDT) at theωB97X−D/6‐311G(d,p) level. While Electron Localization Function (ELF) topological analysis of the reagents indicates that coordination of Cr(CO)3to the aromatic ring of styrene does not cause any remarkable change in its electronic structure, it increases its global electrophilicity but does not efficiently activate the C−C double bond. Thus, the DA reaction of styrene with Cp, which has a high activation energy, 15.9 kcal ⋅ mol−1, is decreased by only 2.1 kcal ⋅ mol−1with the formation of the corresponding Cr(CO)3complex. This DA reaction isendoandantistereoselective. Analysis of the geometrical parameters and the electron density distribution at theendoTSs confirms that coordination of the Cr(CO)3complex to the aromatic ring of styrene does not produce any appreciable change at the corresponding TSs. These DA reactions, which have low polar character, take place through a one‐step mechanismviaan asynchronousendoTS, in which the formation of the C4−C5 simple bond is more advanced than the C1−C6 one. The present MEDT study shows that the Cr(CO)3complex has no effective catalytic activity in the non‐polar DA reactions of styrene with Cp.
Dynamic simulation of CFRP‐shear strengthening on existing square RC members under unequal lateral impact loading
Authors: Al‐Bukhaiti Khalil , Yanhui Liu , Shichun Zhao , Abas Hussein 
Published: June 2022

AbstractWith the plethora of data on how CFRP layers enhance RCs under static loads, research on how the reinforced structural components react to unequal lateral impact loads from a derailed train striking metro station columns or a car accident is lacking. A similar motivation inspired the current study, which sought to create a numerical technique backed by actual testing to evaluate RC members with CFRP in a range of unequal lateral impact scenarios. This paper uses explicit nonlinear finite element techniques to numerically analyze the response of unequal lateral impact‐loaded RC members wrapped in (CFRP) layers. Diverse variables related to CFRP, concrete, steel reinforcement, and impact energy are investigated. This kind of thorough analysis provides unique insights to strengthen RC members against unequal lateral impact loads. The effects of internal forces and deflections, as well as absorbed energy on the impact response of CFRP‐RC components, were investigated and verified by prior experimental results. A parametric sensitivity analysis was conducted after the strain characteristics of steel bars confirmed the finite element model, reinforcement ratio, impact velocity, CFRP properties, and ductility index all influence the member's impact response. This study's results will help advance the field's understanding of CFRP‐RC components analysis and design under unequal lateral impact.
Long noncoding RNA ST8SIA6‐AS1 promotes cell proliferation and metastasis in triple‐negative breast cancer by targeting miR‐145‐5p/CDCA3 to inactivate the p53/p21 signaling pathway
Authors: Qiao Yan , Wang Bin , Yan Yu , Niu Ligang 
Published: June 2022

AbstractBackgroundTriple‐negative breast cancer (TNBC), the most aggressive subtype of breast cancer, always exhibits a poor prognosis due to high risk of early recurrence and distant metastasis. Long noncoding RNAs (lncRNAs) have been reported as crucial regulators in breast cancer. However, the functions and action mechanisms of lncRNA ST8SIA6‐AS1 in TNBC are largely unknown.MethodsQuantitative real‐time PCR and western blot assays were used to measure the expression levels of different genes and proteins. Cell proliferation ability was monitored by CCK‐8, colony forming and flow cytometry assays. Wound healing and transwell assays were performed to evaluate cell migration and invasion. The regulatory mechanisms of ST8SIA6‐AS1 in TNBC were confirmed by dual luciferase reporter and RIP assays. A mouse xenograft model was established to investigate the role of ST8SIA6‐AS1 in TNBC tumor growth.ResultsST8SIA6‐AS1 displayed a higher expression in TNBC cells. Silencing ST8SIA6‐AS1 impaired cell proliferation, cell cycle progression, migration, and invasion in vitro, and slowed tumor growth in vivo. Mechanistically, ST8SIA6‐AS1 could facilitate the expression of its target CDCA3 (cell division cycle associated protein 3) and inactivate the p53/p21 signaling by inhibiting miR‐145‐5p. Moreover, miR‐145‐5p exerted a tumor‐suppressive activity by targeting CDCA3. The tumor‐suppressive effects induced by ST8SIA6‐AS1 knockdown were abated by the down‐regulation of miR‐145‐5p or the up‐regulation of CDCA3.ConclusionST8SIA6‐AS1 exerts an oncogenic role in TNBC by interacting with miR‐145‐5p to up‐regulate CDCA3 expression and inactivate the p53/p21 signaling, highlighting ST8SIA6‐AS1 as a promising molecular target to combat TNBC.
A 2‐Aza‐3,4‐Diphospha‐1‐Bora‐Butadiene
Authors: Rothe Julia , Bresien Jonas , Reiß Fabian , Villinger Alexander , Beweries Torsten , Schulz Axel 
Published: June 2022

AbstractThe reaction of a lithiated supermesityl‐substituted amino‐diphosphene with boron trichloride yielded a formal 2‐aza‐3,4‐diphospha‐1‐bora‐heterobutadiene after LiCl elimination. X‐ray structure and bonding analyses revealed a planar trans‐bent B−N‐P−P framework with short B−N and P−P bond lengths in accord with the description as a heterobutadiene derivative.
An assessment on effect of process parameters on pull force during pultrusion
Authors: Mukherji Arindam , Njuguna James 
Published: June 2022

AbstractThis research investigates the process behaviour by prediction of the pull force required to drag the raw materials through heated die at different reinforcing material configuration during pultrusion. Pultrusion is a continuous manufacturing process that is widely used in manufacture for composite profiles. A specially designed device, friction force by virtue of pulling on ‘resin impregnated’ fibres with both liquid resin and partially cured resin, was employed to measure pulling force against temperature and resin conversion. This allowed to experimentally simulate materials tracing in short and long die length used in process. Differential scanning calorimetry (DSC) was used to determining polymer conversion. The results shows that the downstream part of a die has no significant effect on the pulling force before a specific conversion level is achieved and that higher resin conversion leads to a higher friction at viscous/liquid zone. The difference noted is much more significant when the temperature is low (e.g. room temperature) and considerably drops due to on rising temperature. Further, a new mathematical model is proposed that predicts the rise in compaction pressure on increasing fibre volume fraction and drag velocity which is an opposite characteristic to tapping angle and part thickness considerations. Similarly, many parameters including shrinkage, viscous force and dry friction were modelled and simulated for ortho polyester resins as a function of temperature and resin conversion during dynamic pulling. The study has direct application in configuring pultrusion manufacturing customisation for a specific configured material, components manufacturing and respective designing of the die for the profile to be manufactured.
Perioperative Care Pathways in Low‐ and Lower‐Middle‐Income Countries: Systematic Review and Narrative Synthesis
Authors: Patel Jignesh , Tolppa Timo , Biccard Bruce M. , Fazzini Brigitta , Haniffa Rashan , Marletta Debora , Moonesinghe Ramani , Pearse Rupert , Vengadasalam Sutharshan , Stephens Timothy J. , Vindrola‐Padros Cecilia 
Published: June 2022

AbstractBackgroundSafe and effective care for surgical patients requires high‐quality perioperative care. In high‐income countries (HICs), care pathways have been shown to be effective in standardizing clinical practice to optimize patient outcomes. Little is known about their use in low‐ and middle‐income countries (LMICs) where perioperative mortality is substantially higher.MethodsSystematic review and narrative synthesis to identify and describe studies in peer‐reviewed journals on the implementation or evaluation of perioperative care pathways in LMICs. Searches were conducted in MEDLINE, EMBASE, CINAHL Plus, WHO Global Index, Web of Science, Scopus, Global Health and SciELO alongside citation searching. Descriptive statistics, taxonomy classifications and framework analyses were used to summarize the setting, outcome measures, implementation strategies, and facilitators and barriers to implementation.ResultsTwenty‐seven studies were included. The majority of pathways were set in tertiary hospitals in lower‐middle‐income countries and were focused on elective surgery. Only six studies were assessed as high quality. Most pathways were adapted from international guidance and had been implemented in a single hospital. The most commonly reported barriers to implementation were cost of interventions and lack of available resources.ConclusionsStudies from a geographically diverse set of low and lower‐middle‐income countries demonstrate increasing use of perioperative pathways adapted to resource‐poor settings, though there is sparsity of literature from low‐income countries, first‐level hospitals and emergency surgery. As in HICs, addressing patient and clinician beliefs is a major challenge in improving care. Context‐relevant and patient‐centered research, including qualitative and implementation studies, would make a valuable contribution to existing knowledge.
Intimate Partner Homicide Against Women Typology: Risk Factor Interaction in Spain
Authors: Santos-Hermoso Jorge , González-Álvarez José Luis , Alcázar-Córcoles Miguel Ángel , Carbonell-Vayá Enrique José 
Published: June 2022

AbstractThis investigation studied the interaction between seven risk factors included in the police risk assessment of the VioGén System and found that these factors formed groups based on the dimensions of violence and psychopathology. The 171 femicides analysed were categorised into four groups: normalised (23.4%), violent (25.7%), pathological (18.7%), and pathological/violent (32.2%). These groups exhibited significant differences concerning their psychosocial profile and relationship dynamics. One of the main findings is the identification of the pathological type that had not been detected in previous typologies, thus highlighting the importance of the psychological factor when classifying the perpetrators of femicide. These results have important practical implications, as the classification of the aggressor could be a preliminary step taken before the risk assessment, which would make it possible to individualise predictions and improve the protection of the victims as well as the therapies and intervention programmes.
A Systems-Based Approach to Green Criminology
Authors: Tourangeau Wesley 
Published: June 2022

AbstractGreen criminology is grounded in debates regarding the ethics, legality, and reality of harms vis-à-vis the lives of non-human animals and the environment. The complex, uncertain, and ambiguous nature of these harms reveals the need for a more holistic approach: one that more firmly ties together social and ecological systems. In this paper, key aspects of systems thinking (e.g., leverage points) are outlined to illustrate the value of a systems-based approach. While not completely absent from green criminology literature, systems thinking offers a well-spring of underutilized ideas, concepts, theories, and frameworks that warrant further attention. A systems-based approach to green criminology is presented as a means to (re)imagine, (re)define, (re)examine, and respond to environmental harms.
‘A Real Gap’: Consequences of Removing Reintegration Support in Tasmania, Australia
Authors: Herrlander Birgerson Ebba , Dwyer Angela 
Published: June 2022

AbstractAs Australian imprisonment and recidivism rates continue to rise, it is increasingly important to better understand how to support “returning citizens” to adequately prepare them for post-release life. Using a case study approach focused on service provider perspectives, this article examines the consequences of removing a transitional accommodation support service on service providers and returning citizens. Participants highlighted significant consequences, such as: gaps in services; lack of support and housing; persons remaining in the system unnecessarily; persons being released without transitional support or accommodation; health implications; loss of relationships and trust; and suicide of returned citizens. Drawing on critical criminological theory, we argue that the most significant consequence was the loss of “floating support”—which involves a case worker who brokers support between agencies working with a single client—that was integrated into the program. Study findings suggest serious consequences of government decisions to defund programs in this sector.
Analysis of perioperative problems related to intraocular Implantable Collamer Lens (ICL) implantation
Authors: Zhang Hao , Gong Rui , Zhang Xiaolan , Deng Yingping 
Published: June 2022

Abstract
Purpose
To introduce a modified procedure of ICL implantation, to summarize the perioperative problems and their corresponding treatment after myopia correction with Implantable Collamer Lens (ICL), and to compare the difference of complications between the no-hole ICL and hole ICL.

Methods
We searched all articles on ICL-related perioperative problems and their corresponding treatment in Scopus, Embase, PubMed and Web of Science databases for the last 22 years.

Results
ICL implantation is safe, effective, stable and predictable in the correction of myopia, hyperopia and astigmatism, but can also cause a series of perioperative problems, including intraoperative and postoperative complications.

Conclusion
There are many kinds of complications related to ICL, but the common intraoperative and postoperative complications mainly include abnormality of arch height, abnormal position of ICL, loss of corneal endothelial cells and corneal decompensation, high intraocular pressure and secondary glaucoma, cataract and night vision symptoms. Compared with ICL without central pore, the incidence of complications such as loss of corneal endothelial cells and corneal decompensation, high intraocular pressure and secondary glaucoma and cataract was relatively lower in central hole ICL, while postoperative complications such as night vision symptoms were obvious.
Telehealth provider experience in reproductive endocrinology and infertility clinics during the COVID-19 pandemic and beyond
Authors: Dilday Elizabeth A. , Douglas Christopher R. , Al-Safi Zain A. 
Published: June 2022

Abstract

Purpose
To assess telehealth services offered by reproductive endocrinology and infertility specialists and to gauge provider experiences with incorporating telehealth into their practices.

Methods
A 16-question web-based survey on use of telehealth was distributed to Society for Assisted Reproductive Technology (SART) clinics and to Society for Reproductive Endocrinology and Infertility (SREI) members. Clinic demographic data, telehealth descriptive data, and provider satisfaction with use of telehealth were assessed. Results were collected via Survey Monkey.

Results
A total of 1160 individuals (330 SART clinic contacts and 830 SREI members) were reached via email with an 18.6% (216) survey response rate. All respondents indicated that they offer telehealth visits. Several telehealth platforms were used, with Zoom (62.7%) and telehealth through the clinic’s electronic medical record platform (34.8%) being the most common. The majority of participants (87.0%) anticipate they will offer telehealth visits after the COVID-19 pandemic. Roughly two-thirds (64.4%) of respondents anticipate fewer telehealth visits after the pandemic because of logistics, cost, and patient/provider preference. Nearly all providers are either “very satisfied” (66.2%) or “somewhat satisfied” (31.0%) with telehealth overall.

Conclusion
Telehealth enabled safe patient-provider interactions throughout the COVID-19 pandemic. While only one-third of survey respondents offered telehealth services before the pandemic, nearly all providers express satisfaction with telehealth and anticipate they will offer telehealth services henceforth.
“Everybody Wants to be Included”: Experiences with ‘Inclusive’ Strategies in Physical Education
Authors: Holland Katherine , Haegele Justin A. , Zhu Xihe , Bobzien Jonna 
Published: June 2022

AbstractThis study examined how students with orthopedic impairments experienced strategies identified in the literature to support ‘inclusion’. An interpretative phenomenological analysis research approach was used, and six students with orthopedic impairments (age 10–14 years) served as participants. Data sources were written prompts, semi-structured, audiotaped interviews, and reflective interview notes. Based on thematic data analysis, four themes were constructed: “It’s kind of embarrassing”: experiences with support; “I don’t want to be different”: equipment, activity, and rule modifications; “I like to be a part of the conversation”: autonomy and choice in PE; and “I would rather be like the other students”: discussing disability. The experiences portrayed through these themes highlighted the differential effects of these explicated strategies, where each strategy contributed to feelings of inclusion, as well as marginalization among participants. As such, the findings indicated that ‘inclusive’ strategies should not be considered as blanket recommendations; instead, attempts to promote ‘inclusion’ of students with disabilities should start with a reflexive look at the unique needs of each individual student.
Magnesium Fluoride Borate Glasses for Low Phonon Energy
Authors: Abdel-baki M. , Mostafa Ayman M. , Azooz M. A. , Fayad A. M. 
Published: June 2022

AbstractAn oxyflouroborate glass series of composition 75B2O3-5Al2O3–(20-x) Li2O–xMgF2(where x = 0, 5, 10, and 15 mol.%) was prepared using the normal melt-quenching technique. The physical properties (density, molar volume, and different optical behaviors) of the glass system were investigated via different techniques and discussed with the substitution of Li2O for MgF2. Also, the absorption coefficient, both direct and indirect optical energy gaps, and the optical exciton energy gap were studied. Furthermore, IR spectroscopy was used as a structural probe of the nearest-neighbor environment in the glass network. The results elucidate that the replacement of Li2O with MgF2leads to both a blueshift in absorption cutoff and a decrease in the direct energy gap. More liberation of Mg+2ions produces more localized states during transition, which decreases the values of band gap energy. The addition of MgF2has a clear impact on lowering the glass phonon energy, which makes this glass promising for fiber amplifiers that operate at certain telecommunications wavelength bands and for upconversion fiber lasers. These results show the capability of using oxyflouroborate glass series to be applicable in optical amplifier laser components.
Sustainable management of transboundary pests requires holistic and inclusive solutions
Authors: Prasanna Boddupalli M. , Carvajal-Yepes Monica , Kumar P. Lava , Kawarazuka Nozomi , Liu Yanyan , Mulema Annet Abenakyo , McCutcheon Steven , Ibabao Xenina 
Published: June 2022

AbstractGlobalization and changing climates are aggravating the occurrence and impacts of transboundary pests, and driving the emergence of new threats. Most of the low- and middle-income countries in Africa, Asia and Latin America are not fully prepared in terms of surveillance, diagnostics, and deployment of plant health solutions due to several factors: adequate investment is lacking; knowledge is inadequate; and connections from the local to global, and global to local are insufficient. Effectively countering the current and emerging threats to plant health requires a holistic approach that includes: 1) globally coordinated diagnostic and surveillance systems; 2) epidemiological modelling, risk assessment, forecasting and preparedness for proactive management and containment; and 3) implementation of context-sensitive, eco-friendly, gender-responsive and socially inclusive integrated disease and pest management approaches to reduce the impacts of devastating transboundary pests and diseases. Despite several success stories where major pests and diseases have been brought to control through integrated approaches, further multi-institutional and multi-disciplinary efforts are necessary. Plant health management requires stronger interface between the biophysical and social sciences, and empowerment of local communities. These reflections derive from the proceedings of a webinar on “Transboundary Disease and Pest Management,” organized by CGIAR (Consultative Group on International Agricultural Research) on March 3, 2021, in recognition of the United Nations designated International Year of Plant Health.
Circ_0000705 facilitates proline metabolism of esophageal squamous cell carcinoma cells by targeting miR-621/PYCR1 axis
Authors: Qian Cui-juan , Tong Yi-yang , Wu Lin-ken , Wang Yi-chao , Teng Xiao-sheng , Yao Jun 
Published: June 2022

AbstractCircRNAs have been found to play crucial roles in the metabolism and progression of cancers, but their roles and mechanisms in esophageal squamous cell carcinoma (ESCC) have not been fully elucidated. This work is aimed to explore the role and mechanism of hsa_circ_0000705 (circ_0000705) in ESCC. Circ_0000705 expression was up-regulated in ESCC tissues and cell lines, and high circ_0000705 expression was correlated with poor survival. Circ_0000705 facilitated cell proliferation, invasion, migration and proline metabolism of ESCC cells. The inhibitory effects of circ_0000705 knockdown on cell invasion, migration and proline metabolism were partly rescued by miR-621 inhibition or PYCR1 over-expression. Furthermore, circ_0000705 expression is negatively correlated with miR-621 expression, and positively correlated with PYCR1 in ESCC tissues. Mechanistically, circ_0000705 acted as a ceRNA by sponging miR-621, thereby facilitating PYCR1 expression in ESCC cells. In conclusion, circ_0000705 promoted proline metabolism and malignant progression of ESCC by regulating the miR‑621/PYCR1 axis.
Learning classical readout quantum PUFs based on single-qubit gates
Authors: Pirnay Niklas , Pappa Anna , Seifert Jean-Pierre 
Published: June 2022

AbstractPhysical unclonable functions (PUFs) have been proposed as a way to identify and authenticate electronic devices. Recently, several ideas have been presented to that aim to achieve the same for quantum devices. Some of these constructions apply single-qubit gates in order to provide a secure fingerprint of the quantum device. In this work, we formalize the class of classical readout quantum PUFs (CR-QPUFs) using the statistical query (SQ) model and explicitly show insufficient security for CR-QPUFs based on single-qubit rotation gates, when the adversary has SQ access to the CR-QPUF. We demonstrate how a malicious party can learn the CR-QPUF characteristics and forge the signature of a quantum device through a modelling attack using a simple regression of low-degree polynomials. The proposed modelling attack was successfully implemented in a real-world scenario on real IBM Q quantum machines. We thoroughly discuss the prospects and problems of CR-QPUFs where quantum device imperfections are used as a secure fingerprint.