bluuebunny/crossref_metadata_2025_split huggingface dataset:
Individual and community level predictors of utilization of deworming medications among pregnant women in Ethiopia: A multilevel analysis
Authors: Aragaw Fantu Mamo , Belay Daniel Gashaneh , Endalew Mastewal , Asratie Melaku Hunie , Gashaw Moges , Tsega Nuhamin Tesfa 
Published: September 2022

Background
Deworming is one strategy for reducing the burden of anaemia in pregnant women caused by intestinal parasites and it is one of the components of prenatal treatment offered to pregnant women in Ethiopia during antenatal care visits. However, there is limited evidence on the levels of deworming utilization and its determinants in Ethiopia. Hence, this study was aimed to assess the levels of deworming utilization and its individual and community level determinants among pregnant women in Ethiopia.

Method
This study used a total weighted sample of 7590 reproductive-aged women who gave birth in the five years preceding the survey from the 2016 EDHS data. The data were cleaned and weighted using STATA version 16. Results were presented with tables and texts. Individual and community level determinants for deworming use among Ethiopian pregnant women were identified using a multilevel binary logistic regression model. In the multivariable multilevel analysis, those variables with p-value < 0.05 were considered to be significantly associated with utilization of deworming medication and reported with adjusted odd ratio with 95% confidence level.

Results
The overall utilization of deworming among pregnant women was 5.69% (95% CI: 5.24%, 6.33) in Ethiopia. Having occupation [AOR = 1.59; 95% CI; 1.27, 1.99], wanted pregnancy [AOR = 1.51; 95% CI; [1.16, 1.95], having ANC visit [AOR = 2.72; 95% CI; 2.03,3.64], media exposure [AOR = 1.67; 95%CI; 1.30,2.15], and high community level poverty [AOR = 0.59; 95% CI; 0.40,0.87] were significantly associated with utilization of deworming among pregnant women’s.

Conclusion
According to the findings of this study, out of twenty pregnant women, only one pregnant woman utilizes deworming medication in Ethiopia. Pregnant woman having an occupation, being exposed for media, having wanted pregnancy, having ANC visits and live with low level community poverty were more likely to use deworming medication. Therefore, intervention efforts to enhance utilization of deworming in Ethiopia requires working on enabling factors like media exposure, ANC visit and pregnancy desirability. In addition, Furthermore, increasing the community’s economic capacity could support in increasing deworming medication uptake.
Occurrence of yellow fever outbreaks in a partially vaccinated population: An analysis of the effective reproduction number
Authors: Ferreira Fernanda Cristina da Silva Lopes , Bastos Camacho Luiz Antônio , Villela Daniel Antunes Maciel 
Published: September 2022

Background
Yellow fever is endemic in Africa and the Americas, occurring in urban or sylvatic environments. The infection presents varying symptoms, with high case-fatality among severe cases. In 2016, Brazil had sylvatic yellow fever outbreaks with more than 11 thousand cases, predominantly affecting the country’s Southeast region. The state of Minas Gerais accounted for 30% of cases, even after the vaccine had been included in the immunization calendar for at least 30 years.

Methodology and principal findings
We applied parameters described in the literature from yellow fever disease into a compartmental model of vector-borne diseases, using namely generation time intervals, vital host and vector parameters, and force of infection, using macroregions as the spatial unit and epidemiological weeks as the time interval. The model permits obtaining the reproduction number, which we analyzed from reported cases of yellow fever from 2016 to 2018 in residents of the state of Minas Gerais, Brazil. Minas Gerais recorded two outbreak periods, starting in EW 51/2016 and EW 51/2017. Of all the reported cases (3,304), 57% were men 30 to 59 years of age. Approximately 27% of cases (905) were confirmed, and 22% (202) of these individuals died. The estimated effective reproduction number varied from 2.7 (95% CI: 2.0–3.6) to 7.2 (95% CI: 4.4–10.9], found in the Oeste and Nordeste regions, respectively. Vaccination coverage in children under one year of age showed heterogeneity among the municipalities comprising the macroregions.

Conclusion
The outbreaks in multiple parts of the state and the estimated Re values raise concern since the state population was partially vaccinated. Heterogeneity in vaccination coverage may have been associated with the occurrence of outbreaks in the first period, while the subsequent intense vaccination campaign may have determined lower Re values in the second period.
Intelligibility of speech produced by sighted and blind adults
Authors: Ménard Lucie , Trudeau-Fisette Pamela , Tiede Mark Kenneth 
Published: September 2022

Purpose
It is well known that speech uses both the auditory and visual modalities to convey information. In cases of congenital sensory deprivation, the feedback language learners have access to for mapping visible and invisible orofacial articulation is impoverished. Although the effects of blindness on the movements of the lips, jaw, and tongue have been documented in francophone adults, not much is known about their consequences for speech intelligibility. The objective of this study is to investigate the effects of congenital visual deprivation on vowel intelligibility in adult speakers of Canadian French.

Method
Twenty adult listeners performed two perceptual identification tasks in which vowels produced by congenitally blind adults and sighted adults were used as stimuli. The vowels were presented in the auditory, visual, and audiovisual modalities (experiment 1) and at different signal-to-noise ratios in the audiovisual modality (experiment 2). Correct identification scores were calculated. Sequential information analyses were also conducted to assess the amount of information transmitted to the listeners along the three vowel features of height, place of articulation, and rounding.

Results
The results showed that, although blind speakers did not differ from their sighted peers in the auditory modality, they had lower scores in the audiovisual and visual modalities. Some vowels produced by blind speakers are also less robust in noise than those produced by sighted speakers.

Conclusion
Together, the results suggest that adult blind speakers have learned to adapt to their sensory loss so that they can successfully achieve intelligible vowel targets in non-noisy conditions but that they produce less intelligible speech in noisy conditions. Thus, the trade-off between visible (lips) and invisible (tongue) articulatory cues observed between vowels produced by blind and sighted speakers is not equivalent in terms of perceptual efficiency.
Development and real-life use assessment of a self-management smartphone application for patients with inflammatory arthritis. A user-centred step-by-step approach
Authors: Beauvais Catherine , Pham Thao , Montagu Guillaume , Gleizes Sophie , Madrisotti Francesco , Lafourcade Alexandre , Vidal Céline , Dervin Guillaume , Baudard Pauline , Desouches Sandra , Tubach Florence , Le Calvez Julian , de Quatrebarbes Marie , Lafarge Delphine , Grange Laurent , Alliot-Launois Françoise , Jeantet Henri , Antignac Marie , Tropé Sonia , Besset Ludovic , Sellam Jérémie ,   on behalf of Therapeutic patient education group of the French Society of Rheumatology and Club Rhumatismes et Inflammations
Published: September 2022

Background
Mobile health applications (apps) are increasing in interest to enhance patient self-management. Few apps are actually used by patients and have been developed for patients with inflammatory arthritis (IA) treated with disease-modifying anti-rheumatic drugs which use entails risk of adverse effects such as infections.

Objective
To develop Hiboot, a self-management mobile app for patients with IA, by using a user-centred step-by-step approach and assess its real-life use.

Methods
The app development included first a qualitative study with semi-guided audiotaped interviews of 21 patients to identify the impact of IA on daily life and patient treatments practices and an online cross-sectional survey of 344 patients to assess their health apps use in general and potential user needs. A multidisciplinary team developed the first version of the app via five face-to-face meetings. After app launch, a second qualitative study of 21 patients and a users’ test of 13 patients and 3 rheumatologists led to the app’s current version. The number of app installations, current users and comments were collected from the Google Play store and the Apple store.

Results
The qualitative study revealed needs for counselling, patient–health professional partnership, and skills to cope with risk situations; 86.8% participants would be ready to use an app primarily on their rheumatologist’s recommendation. Six functionalities were implemented: a safety checklist before treatment administration, aids in daily life situations based on the French academic recommendations, treatment reminders, global well-being self-assessment, periodic counselling messages, and a diary. The Hiboot app was installed 20,500 times from September 2017 to October 2020, with 4300 regular current users. Scores were 4.4/5 stars at Android and iOS stores.

Conclusion
Hiboot is a free self-management app for patients with IA developed by a step-by-step process including patients and health professionals. Further evaluation of the Hiboot benefit is needed.
Dietary patterns and associated factors among pregnant women in Ibadan, Nigeria: Evidence from Ibadan pregnancy cohort study
Authors: Adeoye Ikeola A. , Okekunle Akinkunmi P. 
Published: September 2022

BackgroundMaternal nutrition is vital for an optimal intrauterine environment, foetal development, birth weight, pregnancy and neonatal outcomes. We assessed the maternal dietary patterns using a data-driven technique and the associated sociodemographic factors among pregnant women in Ibadan, Nigeria.MethodologyDietary assessment was performed during the enrolment of participants for the Ibadan Pregnancy Cohort Study, a prospective cohort study, conducted among 1745 pregnant women enrolled early in pregnancy (≤ 20 weeks) at four comprehensive obstetric facilities within the Ibadan metropolis. A qualitative food frequency questionnaire was used to assess the pregnant population’s intake of food and drinks three months prior to their enrollment. We determined dietary patterns by applying principal component analysis with a varimax rotation. Multivariate analysis was used to investigate the association between sociodemographic factors and dietary patterns at 5% statistical significance.ResultsMean age and gestational age at enrolment were 29.8 (± 5.3) years and 16.4 (±4.2) weeks, respectively. White rice was the most frequently consumed meal [794 (45.5%) daily, 898 (51.4%)] weekly in our study population. Five major dietary patterns were identified, and they accounted for 28.8% of the total variation: "protein-rich diet with non-alcoholic beverages" (15.6%); "fruits" (4.1%); "typical diet with alcohol" (3.8%); "legumes" (2.8%), "refined grains" (2.6%). Maternal education and income were inversely associated with the consumption of a "protein-rich diet with non-alcoholic beverages", "typical diet with alcohol", and "legumes" in a dose-response fashion. Also, employed women had a higher mean intake of fruits [adjusted β: 0.33 (0.02; 0.65) p = 0.040] compared with women without employment.Conclusions and recommendationWe described five dietary patterns of pregnant women using a data-driven technique, principal component analysis, in Nigeria. We also identified factors influencing maternal dietary patterns, which can inform public health interventions, especially behavioural change communication during antenatal care.
Examining the mental health of siblings of children with a mental disorder: A scoping review protocol
Authors: Krzeczkowski John E. , Wade Terrance J. , Andrade Brendan F. , Browne Dillon , Yalcinoz-Ucan Busra , Riazi Negin A. , Yates Elizabeth , Tagalakis Andrea , Patte Karen A. 
Published: September 2022

Introduction
Mental disorders affect 1 in 5 children having consequences for both the child and their family. Indeed, the siblings of these children are not insulated from these consequences and may experience elevated levels of psychological distress, placing them at increased risk for developing mental disorders. This protocol describes the methodology for a scoping review that will examine how mental disorders in children impact the mental health of their sibling(s). Further, we aim to examine the role of sex, gender, birth order, age of each child, and familial factors (e.g., parent mental illness, family structure), in sibling mental health. The proposed review will also identify resources that aim to support the needs of siblings of children with mental disorders. Taken together, this proposed review aims to take a fundamental step towards determining intervention targets to reduce the transmission of risk between siblings.

Aim
The proposed scoping review aims to address the following questions: i) how do mental disorders (in children <18 years of age) impact the mental health of their sibling(s) (also <18 years of age)? ii) Can we identify resources designed to address the needs of siblings of children with mental disorders?

Methods
We will conduct the proposed scoping review in keeping with the six-stage Arksey and O’Malley Framework and the scoping review methodology provided by the Joanna Briggs Institute. In section i) we outline our research questions. In section ii) we describe our process for identifying studies that examine the mental health of siblings of a child with a mental disorder and studies that provide evidence on resources directed specifically at these siblings. We will search peer-review and grey literature published between 2011 and 2022 from OVID MEDLINE, OVID EMBASE, CINAHL Complete, Proquest Nursing and Allied Health, PsycINFO (via APA platform), Proquest Sociology Collection and Web of Science Core Collection and Proquest Theses and Dissertations. Section iii) describes our process for selecting relevant studies. In sections iv and v, we describe our methods for charting and summarizing relevant data. Finally, in section vi) we describe our integrative knowledge translation plan that aims to include knowledge users in interpretating and translating evidence gathered from the proposed review.
Ten years of graduates: A cross-sectional study of the practice location of doctors trained at a socially accountable medical school
Authors: Hogenbirk John C. , Strasser Roger P. , French Margaret G. 
Published: September 2022

Introduction
The study predicted practice location of doctors trained at a socially accountable medical school with education programs in over 90 communities.

Methods
A cross-sectional study examined practice location 10 years after the first class graduated from the Northern Ontario School of Medicine (NOSM), Canada. Exact tests and logistic regression models were used to assess practice location in northern Ontario; northern Canada; or other region; and rural (population <10,000) or urban community.

Results
There were 435 doctors with 334 (77%) practising as family doctors (FPs), 62 (14%) as generalist specialists and 39 (9%) as other medical or surgical specialists. Approximately 92% (128/139) of FPs who completed both UG and PG at NOSM practised in northern Ontario in 2019, compared with 63% (43/68) who completed only their PG at NOSM, and 24% (30/127) who completed only their UG at NOSM. Overall, 37% (23/62) of generalist specialists and 23% (9/39) of other specialists practised in northern Ontario. Approximately 28% (93/334) of FPs practised in rural Canada compared with 4% (4/101) of all other specialists. FP northern Ontario practice was predicted by completing UG and PG at NOSM (adjusted odds ratio = 46, 95% confidence interval = 20–103) or completing only PG at NOSM (15, 6.0–38) relative to completing only UG at NOSM, and having a northern Ontario hometown (5.3, 2.3–12). Rural Canada practice was predicted by rural hometown (2.3, 1.3–3.8), completing only a NOSM PG (2.0, 1.0–3.9), and age (1.4, 1.1–1.8).

Conclusion
This study uniquely demonstrated the interaction of two mechanisms by which medical schools can increase the proportion of doctors’ practices located in economically deprived regions: first, admit medical students who grow up in the region; and second, provide immersive UG and PG medical education in the region. Both mechanisms have enabled the majority of NOSM-trained doctors to practise in the underserved region of northern Ontario.
Haemophilus influenzae serotype b seroprevalence in central Lao PDR before and after vaccine introduction
Authors: Hefele Lisa , Lai Jana , Vilivong Keoudomphone , Bounkhoun Toukta , Chanthaluanglath Valin , Chanthongthip Anisone , Balloch Anne , Black Antony P. , Hübschen Judith M. , Russell Fiona M. , Muller Claude P. 
Published: September 2022

IntroductionVaccination has dramatically reduced invasiveHaemophilus influenzaetype b (Hib) disease worldwide. Hib vaccination was introduced in the Lao PDR in 2009, as part of the pentavalent vaccine. To contribute to the understanding of the epidemiology of Hib in Lao PDR and the protection levels before and after the introduction of the vaccination, we tested serum samples from existing cohorts of vaccine age-eligible children and unvaccinated adolescents for antibodies against Hib.MethodsSerum samples from 296 adolescents born before vaccine introduction and from 1017 children under 5 years (vaccinated and unvaccinated) were tested for anti-Hib antibodies by ELISA. Bivariate analyses were performed to investigate factors associated with long-term protection.ResultsThe vast majority of all participants showed evidence of short- (42.7%) or long-term (56.1%) protection against Hib. Almost all of the unvaccinated adolescents had antibody titers indicating short-term protection and almost half (45.6%) were long-term protected. Nearly all children (>99.0%) were at least short-term protected, even those that were unvaccinated or whose vaccination status was unknown. Among vaccinated children, participants vaccinated more than 1 or 2 years ago and with a mid-upper arm circumference z-score < -2 were less likely to be long-term protected.DiscussionNearly all adolescents born before the introduction of Hib vaccination in the Lao PDR had antibody titers corresponding to at least short-term protection, indicating a high burden of Hib disease at that time. After vaccine introduction, all but four children (>99%) showed at least short-term protection. Possible explanations for the proportion of protected, yet apparently unvaccinated children, may be past infections, cross-reacting antibodies or faulty vaccination documentation. Our results highlight the need for robust surveillance and reporting of invasive Hib disease to determine the burden of disease despite vaccination.
Determination of the optimum definition of growth evaluation for indeterminate pulmonary nodules detected in lung cancer screening
Authors: Lee Jong Hyuk , Hwang Eui Jin , Lim Woo Hyeon , Goo Jin Mo 
Published: September 2022

Objective
To determine the optimum definition of growth for indeterminate pulmonary nodules detected in lung cancer screening.

Materials and methods
Individuals with indeterminate nodules as defined by volume of 50–500 mm3 (solid nodules) and solid component volume of 50–500 mm3 or average diameter of non-solid component ≥8 mm (part-solid nodules) on baseline lung cancer screening low-dose chest CT (LDCT) were included. The average diameters and volumes of the nodules were measured on baseline and follow-up LDCTs with semi-automated segmentation. Sensitivities and specificities for lung cancer diagnosis of nodule growth defined by a) percentage volume growth ≥25% (defined in the NELSON study); b) absolute diameter growth >1.5 mm (defined in the Lung-RADS version 1.1); and c) subjective decision by a radiologist were evaluated. Sensitivities and specificities of diagnostic referral based on various thresholds of volume doubling time (VDT) were also evaluated.

Results
Altogether, 115 nodules (one nodule per individual; 93 solid and 22 part-solid nodules; 105 men; median age, 68 years) were evaluated (median follow-up interval: 201 days; interquartile range: 127–371 days). Percentage volume growth ≥25% exhibited higher sensitivity but lower specificity than those of diametrical measurement compared to absolute diameter growth >1.5 mm (sensitivity, 69.2% vs. 42.3%, p = 0.023; specificity, 82.0% vs. 96.6%, p = 0.002). The radiologist had an equivalent sensitivity (53.9%; p = 0.289) but higher specificity (98.9%; p = 0.002) compared to those of volume growth, but did not differ from those of diameter growth (p>0.05 both in sensitivity and specificity). Compared to the VDT threshold of 600 days (sensitivity, 61.5%; specificity, 87.6%), VDT thresholds ≤200 and ≤300 days exhibited significantly lower sensitivity (30.8%, p = 0.013) and higher specificity (94.4%, p = 0.041), respectively.

Conclusion
Growth evaluation of screening-detected indeterminate nodules with volumetric measurement exhibited higher sensitivity but lower specificity compared to diametric measurements.
Diccionario de aprendizaje de español como lengua extranjera (DAELE)
Authors: Bueno Rejane 
Published: September 2022

La necesidad de atribuir al diccionario un nuevo papel en el proceso de la enseñanza-aprendizaje de idiomas se impulsa por los cambios de paradigmas en este panorama, lo que conlleva una reformulación de los materiales didácticos que se utilizarán en ello. En el marco de la Lexicografía Pedagógica, los repertorios lexicográficos deben dotarse de características específicas que se basarán en aspectos como conocer al usuario al que se destina la obra, en una descripción lingüística de las unidades recopiladas y, principalmente, en una presentación adecuada de esta información al tipo de usuario y a las finalidades específicas de utilización del repertorio. Proponemos, entonces, aportar algunas reflexiones que han tenido lugar en el proyecto de elaboración del DAELE, principalmente en lo relacionado con la información del verbo, que entendemos como una pieza léxica fundamental para que un aprendiz extranjero pueda construir frases adecuadas en la LE. Presentaremos algunos problemas posibles de este tipo de usuario y cuáles han sido las soluciones propuestas por el equipo que trabaja en la elaboración del DAELE para solucionarlos.