bluuebunny/crossref_metadata_2025_split huggingface dataset:
Collaborative organizations involving outdoor recreational users in the management of biological invasions: A coproduction perspective
Authors: DEHEZ Jeoffrey 
Published: April 2022

Abstract
There is growing interest in collaborative actions in the field of biological invasion control. These actions now cover a wide range of situations, and it is important to better understand them in order to promote their development. This article proposes to reflect on this question based on the case of aquatic invasive plants through a study of projects involving the recreational users of lakes located along France’s southwestern coastline. Drawing on analytical tools from service economics, I approached these organisations as coproduction processes. A mixed methods analysis showed that the organisations involving recreational users valorised the users’ operational and relational competences but not their creative or expert competences. These organisations were conditioned as much by the settings in which the plants developed as by the plants themselves. In this context, the recreational users’ involvement added a place-specific dimension to the management of the action, with flexible boundaries. However, this process was also accompanied by a tendency towards the micro-localisation of tasks as well as a certain specialisation in terms of responsibilities, neither of which were very compatible with the spatial dynamics of the plants. Only the professional technicians and managers seemed able to overcome these obstacles. This study hopes to fill a gap in the economic literature on biological invasions and to offer a complementary approach to the traditional public intervention strategies.
Anticancer Activity of Nano Uncaria gambir
Authors: Wardana Andika Pramudya , Aminah Nanik Siti , Kristanti Alfinda Novi , Zahrah Haninda Iffatuz , Fahmi Mochamad Zakki , Yuliati Anita , - Suhaili , Choudhary M. Iqbal 
Published: April 2022

Abstract
Cancer is a disease caused by uncontrolled cell growth. Cancer treatments, such as chemotherapy, have tended to cause adverse effects for patients. An alternative that can be described is the development of natural-based cancer therapies that have relatively low side effects. The development of Na-alginate as a matrix for nanoencapsulation of Uncaria gambir has shown growth inhibition activity against HeLa and T47D cell lines. The EC50 ± SE of U. gambir extract on the HeLa cell line was 1055.14 ± 42.52 µg/mL while on the T47D cell line 297.15 ± 15.41 µg/mL. On the other hand, the Ug-NPs anticancer activity was substantially higher with EC50 ± SE for HeLa cell line 28.12 ± 27.10 µg/mL, and T47D cell line 10.39 ± 3.50 µg/mL. Therefore, the nanoencapsulation of U. gambir extracts has increased solubility, selectivity, and activity.
Identification and validation of immune-related biomarkers based on machine learning in patients with prostate cancer
Authors: Yuan Kaisheng , Zeng Ruiqi , Deng Pengteng , Zhang Aiping , Liu Huiqian , Yao Junjie , Zhang Qin , Liu Hang 
Published: April 2022

Abstract
Objectives This study aims to explore potential diagnostic biomarkers associated with prostate cancer (PCa) and analyze the pathological role of immune cell infiltration in the disease.Methods Six previously published datasets containing gene expression data (GSE8511, GSE14206, GSE46602, GSE55945, GSE69223 and GSE71016) were downloaded from the Gene Expression Omnibus (GEO) database. Take GSE8511, GSE14206, GSE46602 and GSE55945 as the train group (127 PCa cases and 52 normal controls) and GSE69223 and GSE71016 as the test group (63 PCa cases and 62 normal controls). Differentially expressed genes (DEGs) were screened between 127 PCa cases and 52 normal controls. Candidate biomarkers of PCa were then identified via the use of a least absolute shrinkage and selector operation (LASSO) regression model and support vector machine recursive feature elimination (SVM-RFE) analyses. We performed difference analysis of these genes in the test group, with P < 0.05 were regarded statistically significant. The area under the receiver operating characteristic curve (AUC) value was obtained and used to evaluate discriminatory ability in the train group, with hub genes being identified as those with an AUC > 85%. The expression level and diagnostic value of the biomarkers in PCa were further validated in the GSE69223 and GSE71016 dataset. Lastly, CIBERSORT algorithm and ESTIMATE method were employed to assess the relative immune cell infiltrations of each sample.Results AOX1, APOC1, ARMCX1, FLRT3, GSTM2 and HPN were identified as potential PCa diagnostic biomarkers, and these results were validated using the GSE69223 and GSE71016 datasets. Immune cell infiltration analysis revealed that AOX1, APOC1, ARMCX1, FLRT3, GSTM2 and HPN were correlated with Mast cells resting, Macrophages M0, Macrophages M2, Neutrophils, NK cells activated, T cells CD4 memory resting, T cells gamma delta, T cells follicular helper, T cells CD4 naive and B cells memory.Conclusion We adopted a comprehensive strategy to screen biomarkers related to PCa and explore the critical role of immune cell infiltration in PCa. AOX1, APOC1, ARMCX1, FLRT3, GSTM2 and HPN can be used as diagnostic markers of PCa, providing new insights for future studies on the incidence and the molecular mechanisms of PCa.
Analysis of curative effect of low position tourniquet in calcaneal fracture surgery
Authors: fang-lei Xu , Ying Yao , yue Zhang , lu-yi Zhou , ting-ting Shi , li-yu Zhou , Jian Fan , Guang-rong Yu 
Published: April 2022

Abstract
This study was designed to investigate the role and curative effect of low position tourniquet in calcaneal fracture surgery. We studied a total of 42 calcaneal fracture patients who underwent reduction and internal fixation with plate via L-shaped approach with low position tourniquets using a retrospective analysis between January 2018 and July 2020. The fractures were all unilateral and fresh, and they were classified Sanders III and IV. All patients, with mean age of 47.2 years, had no medical complications. Two groups were categorized based on the position of tourniquets during surgery. Tourniquets were put on proximal thighs in one group (high position tourniquet group n=22), and above ankles in another (low position tourniquet group n=20). Observation index were as follows: operation time, tourniquet time, intraoperative bleeding and incision healing, postoperative fracture healing, ankle-hindfoot scoring system (AOFAS score) and visual analogue scale (VAS score), tourniquet complications such as soft tissue injury and deep venous thrombosis (DVT). No significant differences in general condition, fracture type and complications of the two groups before surgery were noted between the two groups (P>0.05). The low position tourniquet group had significantly less foot pain within two weeks after surgery and higher AOFAS scores of motion pain within 4 weeks after surgery than the high position tourniquet group (P<0.05). However, there was no significant difference in AOFAS function scores twelve weeks after surgery between the two groups (P>0.05). In addition, there were one case of DVT and two cases of soft tissue injuries in the high position tourniquet group, while no related complications were found in the low position tourniquet group (P<0.05). The use of low position tourniquet in calcaneal fracture can ensure a clear vision surgery, reduce the incidence of early postoperative pain and related complications, and promote functional rehabilitation. It is a new method worth recommending.
Confronting the double burden of malnutrition yields health and environmental benefits.
Authors: Barrera Emiliano Lopez , Hertel Thomas 
Published: April 2022

Abstract
Prevalence rates of overweight and obesity are increasing across the globe. Here we present a novel framework that extends the UN-FAO’s methodology for assessing undernutrition to also encompass excessive calorie consumption and its association with the evolution of adult Body Mass Indexes (BMI). By incorporating these relationships into a global partial equilibrium model of the food sector (SIMPLE), we develop future trajectories of age-, sex-, and cohort-specific adult BMI across major world regions over the next three decades. This allows for an examination of the dynamics of the double burden of malnutrition between 2015 and 2050. We find that the excessive consumption of calories will play a key role in driving rising BMI levels, particularly in emerging economies. As a consequence of reaching higher levels of BMI at younger ages, future cohorts will increase their exposure to the health risks attributable to overweight and obesity, including coronary heart disease, stroke, site-specific cancers, and type 2 diabetes we use this framework to shed light on the health, food, and environmental security impacts of changing food consumption behavior. A key finding is that the environmental benefits of shifting consumption patterns are dominated by food waste reductions as opposed to changes in dietary composition.
A Recognition Method for Ballasted Railway Subgrade Defects
Authors: Hou Zhezhe , Zhao Weigang , Yang Yong 
Published: April 2022

Abstract
A recognition method based on sparse representation was proposed to solve the problems in subgrade detection with ground penetrating radar (GPR), such as massive data, time-frequency and difference in experience. Based on the propagation characteristics of electromagnetic waves and radar images in subgrade defects, the phase axis of radar images of railway subgrade defects was different from that of normal subgrades. The sparse representation of railway subgrade defects was studied from the aspects of the time domain, and time-frequency domain with compressive sensing theory. The high-frequency horizontal details of the radar images were obtained to reduce redundant data fetching. The demixing points, energy, and variance per block were obtained as time domain eigenvalues, and the high-frequency horizontal details of the radar images and the energy spectrum of the wavelet multiscale spatial were acquired; thus, the feature vectors of the radar signal were extracted by sparse representation. Based on FCM-GANN (fuzzy C-means and generalized regression neural network), rapid recognition of the ballasted railway was realized. Experimental results indicated that the redundancy of data was reduced, and the accuracy of identification was greatly increased.
Effect of catalytic factors of activated carbon and gas stream properties on H2S catalytic conversion
Authors: Liu Bin , Zuo Songlin 
Published: April 2022

Abstract
Catalysts loaded activated carbons are the widely used adsorbents to remove H2S for purification of the gas streams. Virgin carbon, single and mixed catalyst loaded carbon are used as adsorbents. Their performance of H2S catalytic conversion were studied by evaluating their breakthrough curves in order to investigate the effect of catalysts contents, categories, assistant catalysts and virgin carbon properties on the H2S adsorption. The effects of gas stream properties on H2S catalytic adsorption are also investigated. The results show the H2S uptake amount is increased with catalyst contents and the assistant catalysts can enhance H2S catalytic conversion. NaOH loaded carbon has has better catalytic performance than KOH loaded carbon with same contents. Carbons after impregnation keep a relative high pore volume between 2–20 nm, which is beneficial to give full play to the catalysis. The relative humidity and oxygen can enhance the H2S adsorption capacity and play important roles on H2S adsorption. CTC has little effects on the impregnated carbon for H2S catalytic conversion. Carbon impregnated with specific catalyst can accelerate target substance adsorption and will restrict the pore volume for organics adsorption.
Stability analysis of hybrid systems with higher order transverse discontinuity mapping
Authors: Chawla Rohit , Rounak Aasifa , Pakrashi Vikram 
Published: April 2022

Abstract
This article generalizes the implementation of higher order corrections to state transition matrices during instantaneous reversals in hybrid dynamical systems impacting a discontinuity boundary transversally. A closed form expression for saltation terms in systems possessing a degree of smoothness zero is derived. The difference in flight times of two closely initiated trajectories in state space to the impacting surface has been estimated up to O(2). A comparison of the times of impact estimated with the first order approximation reveals that higher order corrections lead to a significant improvement of estimates. Next, two new algorithms to estimate the Lyapunov spectrum and Floquet multipliers for piecewise-smooth systems have been presented using the derived second order corrections. Stability analyses are subsequently carried out using the proposed framework for two representative cases i.e., of a hard impact oscillator and a pair impact oscillator. It is established that the obtained Floquet multipliers and Lyapunov spectrum accurately predict the stability of the dynamical states, as validated by their corresponding bifurcation diagrams.
Personal dose equivalent Hp (0.07) during 68 Ga-DOTA-TATE production procedures
Authors: Wrzesień Małgorzata , Albiniak Łukasz 
Published: April 2022

Abstract
Objective: The work presents the exposure of hands of the personnel of a nuclear medicine department who prepare and administer 68Ga-DOTA-TATE. Materials and methods: Dosimetry measurements were performed during three one-week sessions by using high-sensitivity thermoluminescent detectors. Radiochemists and nurses were included.Results: The greatest exposure to ionizing radiation is in the non-dominant left hand of radiochemists and nurses. The maximum Hp(0.07)/A value of 49.36 ± 4.95 mSv/GBq was registered for radiochemists during the 68Ga-DOTA-DATE activity dispensing procedure. For nurses performing the radiopharmaceutical injection procedure, the maximum value of Hp(0.07)/A was recorded, amounting to 1.28 ± 0.13 mSv/GBq. The dispensing of the dose of 68Ga-DOTA-TATE accounts for approximately 60% of the exposure of radiochemists' fingertips.Conclusions: The authors of the study recommend routine placement of a ring dosimeter on the middle finger of the non-dominant hand of radiochemists and nurses.
Unstable Connectivity Aware Protocol for Dependable Messages Delivery for Future Internet of Vehicles
Authors: Gasmi Rim , Aliouat Makhlouf , Aliouat Zibouda , Seba Hamida 
Published: April 2022

Abstract
In the near future, Internet of Vehicles (IoV) enabling the Intelligent Transportation System paradigm swill undergo a significant change when integrating autonomous vehicles as intelligent and powerfully platform systems. All this would generate huge traffic messages that should be rigorously taken into account in order to ensure dependable message delivery in a real-time manner. Therefore, Timely useful information acquisition in an unstable connectivity environment like IoV is of paramount importance when making a decision that is related to critical events. For instance, saving lives in accident occurrences greatly depends on the urgent messages sent out and received by rescue services. Furthermore, preventing accidents by alerting obstacles impeding road circulation requires stable link communications conveying surely emergency messages to their appropriate destinations. Therefore, the high velocity of vehicles affects negatively node communication links leading to frequent link disconnections. In this paper, we propose to take advantage of the IoV features to choose appropriate metrics aiming to ensure route stability according to two levels. In the first one, the best routes are discovered by using metrics such as signal strength, bandwidth, delay and node velocity. In the second level, an approach for estimating links lifetime has been used. The latter is based on speed and direction parameters in order to find the most durable route. To this end, the Fuzzy Logic method has been used to reach our objective. The performance evaluation of our proposal has been carried out through the NS-3 simulator and the obtained results outperform GICA, QoS Cluster and weight-based protocols.
A cross-sectional study to evaluate predisposing factors for keratoconus in Saudi Arabia
Authors: Abuallut* Ismail Ibrahim , Alomaish Abeer Rihan , Arishy Alshaymaa Mohammad , Mashragi Mariam Asiri , Alfaifi Kholod Hadi , Alnamazi Noura Ali , Moafa Aisha Mansour , Mahfouz Mohamed S. , Moafa Majid A. , Jafaari Sultan A. , Alagsam Abdulaziz A. , Jareebi Mohammad A. 
Published: April 2022

Abstract
In cases of atopy, IgE antibodies are formed in reaction to certain environmental factors like house dust mites, pollen, or even food allergens. Some studies have shown an association between atopic diseases and keratoconus. This study aims to determine the prevalence of atopy and its associated factors among keratoconus patients. A cross-sectional study was conducted among the Jazan population attending ophthalmology clinics in PMNH regardless of their sex. Data collection started in August 2020 and finished in mid June 2021. The sample was selected using the convenience sampling technique and the total sample size was 83 participants. Data were collected via a questionnaire-based interview that contained 46 questions in the Arabic language. The data collected were analyzed using SPSS software. Family history is the leading predisposing factor for keratoconus (P < 0.001). Also, eye rubbing was a significant (P < 0.015) trigger for keratoconus. However, other factors, including demographic factors such as gender and atopic conditions, did not have any significant association. A combination of genetic and environmental factors is the leading cause of the development of keratoconus; however, family history is the most influential factor, followed by eye rubbing.
Investigation on the prevalence of malocclusion and analysis of oral health-related quality of life in children aged 6-12 years in Jinzhou
Authors: Xu Jianhui , Li Xin , Liu Xiaoyu , Li Siwei , Wang Xueqin , Liu Jin 
Published: April 2022

Abstract
Background
Malocclusion can present a variety of clinical forms and manifestations, which affect children's oral health and lead to psychological problems.However, among children in Jinzhou, there are few reports on the prevalence of malocclusion and the effect of malocclusion on oral health-related quality of life.
Methods
A total of 2162 children aged 6−12 years were randomly selected from various districts of Jinzhou. Conventional clinical examination was performed by stomatologists, and the results were described based on the Angle malocclusion classification. Further, questionnaires survey completed by children’s parents or guardians provided the demographic data, life style, and oral habits.
Results
The incidence of malocclusion in children aged 6 to 12 in Jinzhou was 67.90%, including 1129 males and 1033 females, accounting for 52.22% and 47.78% of males and females, respectively.According to Angle's classification, the incidence of Angle Ⅰ, Angle Ⅱ and Angle Ⅲ malocclusion was 46.48%, 8.14% and 12.03%, respectively.If classified according to clinical symptoms, the most common type is dentition crowding, with an incidence of 71.79%.Common risk factors include heredity, bad oral habits and so on. In addition, malocclusion has a negative effect on oral health-related quality of life of children aged 6–12 years in Jinzhou.
Conclusions
The prevalence rate of malocclusion in 6-12-year-old children in Jinzhou is high, children and parents have weak awareness of oral health care. In addition,heredity and bad oral habits are common risk factors for malocclusion. Malocclusion has a negative effect on children's oral health-related quality of life.
Estimation of cancer risks due to chest radiotherapy treatment planning computed tomography (CT) simulations
Authors: Derikvand Afsaneh Mir , Bagherzadeh Saeed , MohammadSharifi Ali , Khoshgard Karim , AllahMoradi Fariba 
Published: April 2022

Abstract
The objective of our study was to determine organ and effective doses to estimate the lifetime attributable risk (LAR) of cancer incidence related to chest tomography simulations for Radiotherapy Treatment Planning (RTTP) using patient-specific information. Patient data from 70 chest CT scans were used to compute effective dose. The effective dose was calculated by two methods: first using ImPACT patient dosimetry calculator software using International Comission on Radiological Protection (ICRP103) weighting factors for a 70 kg patient and then applying related correction factors according to the patient’s weight. Second using the scanner-derived dose-length product. LARs of cancer incidence was computed using the seven Biologic Effects of Ionizing Radiation (BEIR VII) report based on sex and age at each exposure. Mean±standard deviation values were 507.50±142.7 mGy.cm for DLP, 11.04±3.66mGy for CTDIvol, 46.88±6.65 cm for scan length. The mean±standard deviation value for the effective dose was 10.31±2.88mSv using ImPACT patient dosimetry calculator software and 8.62±2.42 mSv using the scanner-derived dose-length product. The mean ± SD of LAR of cancer incidence for all cancers, all solid cancers and leukemia were 65.49±28.54, 61.71±27.24, 6.62±2.46 cases per 100,000 individuals, respectively. Radiation exposure from the usage of CT for radiotherapy treatment planning (RTTP) causes non-negligible increases in lifetime attributable risk. The results of this study can be used as a guide by physicians to implement strategies based on the As Low As Reasonably Achievable (ALARA) princiciple that lead to a reduction dose without sacrificing diagnostic information.
Repair of anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) by sinus pouch technique
Authors: Kumae Masaru , Aoki Mitsuru , Hagino Ikuo , Koshiyama Hiroshi , Ito Takahiro , Nishiori Hironobu 
Published: April 2022

Abstract
Background: ALCAPA is a rare disease. The sinus pouch technique reported in transposition of the great arteries has not been reported to be applied to ALCAPA, but it was a useful method. Case presentation: A five-month-old girl, weighing 5.3 kg, diagnosed ALCAPA underwent emergency surgery. The left coronary artery (LCA) originated from the posterior pulmonary artery (PA), and the left main trunk (LMT) was very short (1.5 mm), with moderate level of mitral valve regurgitation (MR). Because of the low height from the orifice to the pulmonary valve(Pv), it was necessary to avoid the tunneling technique due to concerns about adverse effects on the Pv. The sinus pouch technique was chosen because of its simplicity and low risk of stenosis due to coronary artery bending, especially in cases with short LMT. Conclusion: We report a case of infantile ALCAPA with good results using this technique.