bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of Drug-sensitive and Drug-resistant Tuberculosis Cases among Adults at Tuberculosis Referral Hospitals in Indonesia
Authors: Burhan Erlina , Karyana Muhammad , Karuniawati Anis , Kusmiati Tutik , Wibisono Banteng Hanang , Handayani Diah , Riyanto Bambang Sigit , Sajinadiyasa I Gede Ketut , Sinaga Bintang Yinke Magdalena , Djaharuddin Irawaty , Indah Sugiyono Retna , Susanto Nugroho Harry , Diana Aly , Kosasih Herman , Lokida Dewi , Siswanto  , Neal Aaron , Lau Chuen-Yen , Siddiqui Sophia 
Published: October 2022

ABSTRACT.
As Indonesia’s rifampin resistance testing rates are lower than global testing rates per the 2020 WHO global tuberculosis (TB) report, prevalence of multidrug-resistant TB may be underestimated. Our study aimed to evaluate prevalence and patterns of TB drug resistance (DR) within Indonesia. We conducted a cross-sectional analysis of baseline data collected from 2017–2018 as part of a cohort study of adults with presumed pulmonary TB at 7 DR-TB referral hospitals in Indonesia. Bacteriological examinations (acid-fast bacilli, GeneXpert, sputum culture) and drug-susceptibility testing were performed following the guidelines of the National TB Program. Of 447 participants with complete bacteriological examinations, 312 (69.8%) had positive sputum cultures for Mycobacterium tuberculosis. The proportion of MDR and pre-extensively drug-resistant was higher in previously treated compared with newly diagnosed participants (52.5% [73/139] versus 15% [26/173]). Compared with drug-sensitive case, drug-resistant TB was associated with cavities. Given the difference between rates of DR in TB referral hospitals from our study compared with the WHO survey in 2019 that showed 17.7% and 3.3% DR among previously treated and newly diagnosed participants globally, further characterization of Indonesia’s TB epidemiology in the general population is needed. Strategies, including public policies to optimize case finding, strengthen capacity for resistance testing, and prevent loss to follow-up will be critical to reduce the burden of TB in Indonesia.
KHẢO SÁT ĐẶC ĐIỂM HÌNH ẢNH PHÌNH ĐỘNG MẠCH NÃO VỠ TRÊN CHỤP MẠCH SỐ HÓA XÓA NỀN TẠI BỆNH VIỆN ĐA KHOA TỈNH QUẢNG NINH
Authors: Quang Chức Ngô , Minh Hải Nguyễn , Tuấn Minh Ngô , Xuân Khái Nguyễn 
Published: October 2022

Mục tiêu: Mô tả đặc điểm hình ảnh phình động mạch não vỡ trên chụp mạch số hóa xóa nền (DSA). Đối tượng và phương pháp nghiên cứu: nghiên cứu hồi cứu kết hợp tiến cứu 69 bệnh nhân (BN) được chụp và can thiệp nút phình động mạch não vỡ tại bệnh viện đa khoa tỉnh Quảng Ninh từ 5/2019 đến 7/2022. Kết quả: 46,4% túi phình tại động mạch thông trước, KT trung bình 6,21 ± 2,62mm. 79,7% cổ túi <4mm, ĐK cổ trung bình 2,79 ± 1,13. Tỉ lệ túi/cổ <1,5 chiếm 47,8%. 85,5% bờ túi không nhẵn và 13% có nhánh mạch cổ túi. 5,8% co thắt mạch mang và 8,7% có biến thể mạch máu thiểu sản/bất sản A1 hoặc P1. Kết luận: DSA là phương tiện quan trọng trong quy trình chẩn đoán và điều trị phình động mạch não vỡ.
YẾU TỐ TIÊN LƯỢNG CỦA TRÀN DỊCH NÃO CẤP Ở BỆNH NHÂN CHẢY MÁU DƯỚI NHỆN
Authors: Hồng Khôi Võ , Ngọc Minh Đào , Công Hoàng Nguyễn , Mạnh Dũng Nguyễn 
Published: October 2022

Đặt vấn đề: Tràn dịch não cấp là một trong những biến chứng nguy hiểm của chảy máu dưới nhện. Hiện nay ở Việt Nam cũng như trên thế giới chưa có nhiều công trình nghiên cứu về các yếu tố tiên lượng bệnh của Tràn dịch não cấp sau chảy máu dưới nhện. Mục tiêu: Nghiên cứu các yếu tố tiên lượng bệnh của tràn dịch não cấp ở bệnh nhân chảy máu dưới nhện. Đối tượng và phương pháp nghiên cứu: bệnh nhân chảy máu dưới nhện có biến chứng tràn dịch não cấp điều trị tại Trung tâm Thần kinh, Bệnh viện Bạch Mai. Nghiên cứu mô tả cắt ngang, tiến cứu. Kết quả: Tuổi > 50 có tiên lượng xấu tăng 3,6 lần. Rối loạn ý thức có tiên lượng xấu hơn 3,1 lần so với bệnh nhân tỉnh. Di lệch đường giữa có tiên lượng xấu hơn bệnh nhân không có di lệch (OR 11,5). Giãn não thất mức độ nặng làm tăng nguy cơ xấu đi của bệnh (p < 0,05; OR 4,43). Kết luận: Tuổi cao, rối loạn ý thức, di lệch đường giữa, giãn não thất mức độ nặng là những yếu tố tiên lượng của bệnh
TỔNG QUAN VỀ CHỈ ĐỊNH PHẪU THUẬT CẮT THÙY TUYẾN GIÁP TRONG VI UNG THƯ TUYẾN GIÁP THỂ NHÚ
Authors: Xuân Sơn Trần , Quang Trung Nguyễn , Mạnh Phương Hồ 
Published: October 2022

Mục tiêu: Tổng quan về chỉ định cắt thùy giáp và các yếu tố liên quan đến chỉ định cắt thùy giáp trong vi ung thư tuyến giáp thể nhú. Phương pháp: Tổng quan hệ thống. Chúng tôi tìm kiếm 1 cách hệ thống trên sở dữ liệu PubMed, Medline, thư viện điện tử đại học Y Hà Nội để xác định các bài báo gốc liên quan đến cắt thùy giáp trong ung thư tuyến giáp thể nhú. Kết quả: Có 11 nghiên cứu được lựa chọn vào tổng quan này. Để chỉ định cắt thùy tuyến giáp đối với bệnh nhân vi ung thư tuyến giáp thể nhú cần có lựa chọn bệnh nhân có các yếu tố phù hợp. Kết luận: chỉ định cắt thùy giáp cho vi UTTG với các điều kiện thỏa mãn sau: (1) ung thư tuyến giáp thể nhú và đường kính lớn nhất của nhân ung thư <= 1cm và (2) đơn nhân, (3) tổn thương nằm hoàn toàn trong tuyến giáp, không phá vỡ vỏ trên đại thể, không xâm lấn các cấu trúc xung quanh; (4) không có di căn hạch cổ xác định trên siêu âm trước phẫu thuật và phát hiện được trong phẫu thuật; (5) không có di căn xa; (6) không có tiền sử chiếu xạ vùng cổ; (7) không có tiền sử ung thư tuyến giáp có tính chất gia đình.
PENGEMBANGAN MEDIA POP-UP BOOK BERBASIS AUDIO DAN ANDROID MATERI METAMORFOSIS HEWAN UNTUK KELAS IV SD
Authors: Elen Salsa Bila Melisa , Khoirul Umam Nanang , Wahyuning Subayani Nataria 
Published: October 2022

Abstrak: Penelitian ini bertujuan mengembangkan media Pop-Up Book Berbasis Audio dan Android materi metamorfosis hewan agar peserta didik mampu membedakan dan mengurutkan siklus metamorfosis hewan dengan benar. Berdasarkan hasil penelitian pengembangan model ADDIE yang telah dilakukan menunjukkan bahwa pengembangan media Pop-Up Book Berbasis Audio dan Android materi metamorfosis hewan dapat digunakan dalam proses pembelajaran dengan kategori “sangat baik” berdasarkan hasil persentase ahli media sebesar 91,5% dan ahli materi sebesar 100%, serta angket respon peserta didik dengan skor sebesar 87,6%.
Abstract: This study aims to develop an Audio and Android-based Pop-Up Book media for animal metamorphosis material so that students are able to distinguish and sequence the animal metamorphosis cycle correctly. Based on the results of the research on the development of the ADDIE model that has been carried out, it shows that the development of the Audio and Android-based Pop-Up Book media for animal metamorphosis material can be used in the learning process in the "very good" category based on the results of the percentage of media experts of 91.5% and material experts of 100. %, as well as student response questionnaires with a score of 87.6%.
Interactive biogenic emissions and drought stress effects on atmospheric composition in NASA GISS ModelE
Authors: Klovenski Elizabeth , Wang Yuxuan , Bauer Susanne E. , Tsigaridis Kostas , Faluvegi Greg , Aleinov Igor , Kiang Nancy Y. , Guenther Alex , Jiang Xiaoyan , Li Wei , Lin Nan 
Published: October 2022

Abstract. Drought is a hydroclimatic extreme that causes perturbations to
the terrestrial biosphere and acts as a stressor on vegetation, affecting
emissions patterns. During severe drought, isoprene emissions are reduced.
In this paper, we focus on capturing this reduction signal by implementing a new percentile isoprene drought stress (yd) algorithm in NASA GISS ModelE based on the MEGAN3 (Model of Emissions of Gases and Aerosols from Nature Version 3) approach as a function of a photosynthetic parameter
(Vc,max) and water stress (β). Four global transient
simulations from 2003–2013 are used to demonstrate the effect without
yd (Default_ModelE) and with online yd
(DroughtStress_ModelE). DroughtStress_ModelE is evaluated against the observed isoprene measurements at the Missouri Ozarks AmeriFlux (MOFLUX) site during the 2012 severe drought where improvements in the correlation coefficient indicate it is a suitable drought stress parameterization to capture the reduction signal during severe drought. The application of yd globally leads to a decadal average reduction of ∼2.7 %, which is equivalent to ∼14.6 Tg yr−1 of isoprene. The changes have larger impacts in regions such as the southeastern US. DroughtStress_ModelE is validated using the satellite ΩHCHO column from the Ozone Monitoring Instrument (OMI) and surface O3 observations across regions of the US to examine the effect of drought on atmospheric composition. It was found that the inclusion of isoprene drought stress reduced the overestimation of ΩHCHO in Default_ModelE during the 2007 and 2011 southeastern US droughts and led to improvements in simulated O3 during drought periods. We conclude that isoprene drought stress should be tuned on a model-by-model basis because the variables used in the parameterization responses are relative to the land surface model hydrology scheme (LSM) and the effects of yd application could be larger than seen here due to ModelE not having large biases of isoprene during severe drought.
Sub-millennial climate variability from high-resolution water isotopes in the EPICA Dome C ice core
Authors: Grisart Antoine , Casado Mathieu , Gkinis Vasileios , Vinther Bo , Naveau Philippe , Vrac Mathieu , Laepple Thomas , Minster Bénédicte , Prié Frederic , Stenni Barbara , Fourré Elise , Steen-Larsen Hans Christian , Jouzel Jean , Werner Martin , Pol Katy , Masson-Delmotte Valérie , Hoerhold Maria , Popp Trevor , Landais Amaelle 
Published: October 2022

Abstract. The EPICA Dome C (EDC) ice core provides the longest
continuous climatic record, covering the last 800 000 years (800 kyr). A
unique opportunity to investigate decadal to millennial variability during
past glacial and interglacial periods is provided by the high-resolution
water isotopic record (δ18O and δD) available for the
EDC ice core. We present here a continuous compilation of the EDC water
isotopic record at a sample resolution of 11 cm, which consists of 27 000
δ18O measurements and 7920 δD measurements (covering,
respectively, 94 % and 27 % of the whole EDC record), including
published and new measurements (2900 for both δ18O and δD) for the last 800 kyr. Here, we demonstrate that repeated water isotope
measurements of the same EDC samples from different depth intervals obtained using different analytical methods are comparable within analytical uncertainty. We thus combine all available EDC water isotope measurements to
generate a high-resolution (11 cm) dataset for the past 800 kyr. A
frequency decomposition of the most complete δ18O record and a
simple assessment of the possible influence of diffusion on the measured
profile shows that the variability at the multi-decadal to multi-centennial
timescale is higher during glacial than during interglacial periods and
higher during early interglacial isotopic maxima than during the Holocene.
This analysis shows as well that during interglacial periods characterized
by a temperature optimum at the beginning, the multi-centennial variability
is strongest over this temperature optimum.
Hydrography90m: a new high-resolution global hydrographic dataset
Authors: Amatulli Giuseppe , Garcia Marquez Jaime , Sethi Tushar , Kiesel Jens , Grigoropoulou Afroditi , Üblacker Maria M. , Shen Longzhu Q. , Domisch Sami 
Published: October 2022

Abstract. The geographic distribution of streams and rivers drives a multitude of patterns and processes in hydrology, geomorphology, geography, and ecology. Therefore, a hydrographic network that accurately delineates both small streams and large rivers, along with their topographic and topological properties, with equal precision would be indispensable in the earth sciences. Currently, available global hydrographies do not feature small headwater streams in great detail. However, these headwaters are vital because they are estimated to contribute to more than 70 % of overall stream length. We aimed to fill this gap by using the MERIT Hydro digital elevation model at 3 arcsec (∼90 m at the Equator) to derive a globally seamless, standardised hydrographic network, the “Hydrography90m”, with corresponding stream topographic and topological information. A central feature of the network is the minimal upstream contributing area, i.e. flow accumulation, of 0.05 km2 (or 5 ha) to initiate a stream channel, which allowed us to extract headwater stream channels in great detail. By employing a suite of GRASS GIS hydrological modules, we calculated the range-wide upstream flow accumulation and flow direction to delineate a total of 1.6 million drainage basins and extracted globally a total of 726 million unique stream segments with their corresponding sub-catchments. In addition, we computed stream topographic variables comprising stream slope, gradient, length, and curvature attributes as well as stream topological variables to allow for network routing and various stream order classifications. We validated the spatial accuracy and flow accumulation of Hydrography90m against NHDPlus HR, an independent, national high-resolution hydrographic network dataset of the United States. Our validation shows that the newly developed Hydrography90m has the highest spatial precision and contains more headwater stream channels compared to three other global hydrographic datasets. This comprehensive approach provides a vital and long-overdue baseline for assessing actual streamflow in headwaters and opens new research avenues for high-resolution studies of surface water worldwide. Hydrography90m thus offers significant potential to facilitate the assessment of freshwater quantity and quality, inundation risk, biodiversity, conservation, and resource management objectives in a globally comprehensive and standardised manner. The Hydrography90m layers are available at https://doi.org/10.18728/igb-fred-762.1 (Amatulli et al., 2022a), and while they can be used directly in standard GIS applications, we recommend the seamless integration with hydrological modules in open-source QGIS and GRASS GIS software to further customise the data and derive optimal utility from it.
GEBELERDE PANDEMİDE BESLENME VE COVID-19 FOBİSİ
Authors: EKİNCİ YİĞİT İrem , SEVİM Yonca 
Published: October 2022

Amaç: Bireylerin koronavirüs salgınındaki kaygı durumları beslenme davranışlarını etkilemektedir. Gebelikte beslenme gebe ve fetüs sağlığı açısından önemli bir faktördür. Bu çalışma koronavirüs 19 hastalık (COVID-19) fobisinin gebelerin beslenme durum ve alışkanlıkları üzerindeki etkisini araştırmak amacıyla planlandı.
Yöntem: Kesitsel olarak planlanan bu çalışmaya Nisan-Mayıs 2021 tarihleri arasında İstanbul Sultangazi’de bulunan özel bir tıp merkezi kadın doğum polikliniğine başvuran toplam 87 gebe kadın katıldı. Araştırma verileri araştırmacı tarafından uygulanan anket formu, 24 saatlik besin tüketim kaydı, koronavirüs 19 fobisi ölçeği (C19P-S) ve COVID-19 pandemisinde gebe beslenmesindeki değişimler yüz yüze görüşme tekniği kullanılarak elde edildi.
Bulgular: Gebelerin toplam enerji alım miktarı medyanı 1565kkal/gün ve enerjinin karbonhidrat, protein ve yağdan karşılanan medyan değerleri sırasıyla %45, %15 ve %38’idi. Gebelerin günlük diyetle aldığı mikro besin öğelerinden B1, B6, B9 ve D vitamini ile demir yetersiz alım düzeyinde iken K vitamini ve sodyum alımlarının yüksek alım düzeyinde olduğu saptandı. Bireylerin C19P-S ölçeği toplam puan medyanı 57 olarak bulundu. Gebelerde COVID-19 geçirme ve vefat durumu ile C19P-S ölçeği skorları anlamlı farklılık göstermedi (p>0.05). Bireylerin salgın sürecinde günlük aldıkları besin miktarlarında değişiklik olduğu ve bu değişimin çoğunlukla gebelik sebebiyle olduğu tespit edildi (p
The Fanatic and the Last Man
Authors: Katsafanas Paul 
Published: October 2022

Abstract
Suppose we accept Nietzsche’s claim that critical reflection undermines our evaluative commitments. Then it seems that we are left with a pair of unappealing options: either we engage in critical reflection and find our evaluative commitments becoming etiolated; or we somehow immunize certain evaluative commitments from the effects of critical reflection. Nietzsche considers both of these paths, labeling the person who results from the first path “the last man” and the person who results from the second “the fanatic.” I consider Nietzsche’s analysis of these two character types, discuss why he thinks that in modernity these are the options with which we are faced, and ask whether Nietzsche thinks that there is a third way.
Borrowed Books and Scholarly Interventions in Sarah Josepha Hale’s Genius of Oblivion (1823)
Authors: O’Leary Derek Kane 
Published: October 2022

ABSTRACT
Historical society archives and libraries in the early United States often appear as strictly masculine spaces in which few, if any, women had access and influence. Although scholarship tends to depict these archives and the historical narratives that they promoted in this light, women found a range of ways to engage with these institutions between the American Revolution and the Civil War. Sarah Josepha Hale (1788–1879), prior to her emergence as the most influential magazine editor in the antebellum United States, demonstrates this in her mostly neglected early poem, “Genius of Oblivion” (1823). Through the analysis of her unexamined personal correspondence with New Hampshire librarian Jacob Bailey Moore and a closer reading of her poetry, this article illuminates Hale’s use of her social network to access library materials and engage through poetry with the scholarship of contemporary male authors.
The Essay and the Art of Interpretation: Caygill and Nietzsche
Authors: Howard Stephen 
Published: October 2022

ABSTRACT
This article speculatively reconstructs what I call Howard Caygill’s “unwritten book” on Nietzsche, based on the collection of Caygill’s philosophical essays, Force and Understanding (2021). I propose that an engagement with Nietzsche’s thought runs throughout Caygill’s work, although it would be a mistake to label Caygill a “Nietzschean.” One particularly relevant aspect of Nietzsche’s philosophy is his conception of philological reading. After outlining this, I examine the Nietzsche who emerges from Caygill’s essays and thus the central themes of the “unwritten book.” I close by considering the implications of my account for the distinction between two philosophical forms: the treatise and the essay.
The Philosophical Essay
Authors: Cook Jon 
Published: October 2022

ABSTRACT
Tensions between an idea of philosophy and the practice of the essay are explored in relation to the work of Montaigne in the sixteenth century and Hume in the eighteenth. The comparison between the two lays a basis for thinking about the contrast between philosophy as a way of life and its opposite. The changing and equivocal character of the philosophical essay is further explored with reference to Adorno’s “Essay as Form” and Howard Caygill’s recently published collection, Force and Understanding.
Conversation and Catering: Bernard Shaw and the Winstens—a Symbiotic Relationshipat Ayot St Lawrence and Beyond
Authors: Parker Philippa 
Published: October 2022

ABSTRACT
Clare and Stephen Winsten, artist and writer, were the neighbors of Bernard Shaw during his last decade. They have received cursory, if not denigratory, treatment from Shaw’s biographers for their perceived role in his last years. This article seeks to rescue their reputations and show how their company, after the death of Charlotte Shaw, filled a role in Shaw’s life. By recounting the couple’s earlier lives, it makes clear how much they had in common with Shaw and why he found them satisfying conversationalists. Shaw’s interactions with the Winsten family revived his interest in art patronage and in Pygmalion-style experiments in the development and education of their children. The text identifies the artworks and books, which were created by the couple as a result of their relationship with Shaw, with the aim of rescuing them from later Shavian intellectual snobbery. It was a mutually beneficial friendship.
Mourning Agnes: The Hidden Impact on Bernard Shaw of the Death of His Sister
Authors: Hellman Jesse M. 
Published: October 2022

ABSTRACT
We know very little about Bernard Shaw’s sister Elinor Agnes beyond that she died from consumption just shy of twenty-two years of age. Shaw spoke so little of her, revealing so little of his feelings for her, that we might wonder how important Agnes was to him and how her death affected him. Searching for what is known of Agnes led to a number of clues suggesting a close bond existed between Shaw and his sister. Shaw’s silence regarding the dates of the deaths of his sisters Lucy and Agnes speaks of unresolved mourning and complicated grief. What led Shaw to so protect himself from the emotional pain it appears he experienced from death and loss? Importantly, it appears that Shaw’s memories of Agnes and his wishes for her contributed to the creation of his iconic young heroines.
Shaw’s Village Wooing: Love and Language from A to Z
Authors: Reynolds Jean 
Published: October 2022

ABSTRACT
Although Shaw dismissed Village Wooing as a “very trivial comedietta,” it deserves serious attention. Village Wooing shares several themes with Pygmalion, including a language bet and a contentious relationship between a working-class young woman and a gentleman who corrects her diction. Like Pygmalion, it explores several important language ideas. John Bertolini calls it “a play of reading and writing,” and Peter Gahan describes it as “an encounter between writer and reader.” I have used Walter Ong’s provocative “The Author’s Audience Is Always a Fiction” to examine the complex relationship between an author and a reader in Village Wooing.
Growing Up Like Romola: The Spiritual Evolutions of George Eliot and Bernard Shaw
Authors: Christian Mary 
Published: October 2022

ABSTRACT
Bernard Shaw and George Eliot both criticized traditional religious doctrines and institutions, yet also recognized the strength and sense of purpose religion could offer and sought in their writings to identify some new religion that they could accept as intellectually honest. This article examines Eliot’s efforts to articulate such a principle in her novel Romola (1862–63) and Shaw’s echoes and critiques of her ideas in Major Barbara (1905). While Eliot’s ending calls for a humanistic faith rooted in compassion and fellowship, Shaw dismissed individual compassion as an ineffective substitute for socialist reform. Moreover, whereas Eliot’s novel ultimately rejects the idea of religious institutions, Shaw left the issue unsettled in Major Barbara and returned to it in later writings in an effort to formulate an idea of a widely shared religion grounded in economic equity and cooperation with the Life Force.