bluuebunny/crossref_metadata_2025_split huggingface dataset:
Telomere fragility in radiology workers occupationally exposed to low doses of ionising radiation
Authors: Tričković Jelena Filipović , Šobot Ana Valenta , Joksić Ivana , Joksić Gordana 
Published: April 2022

Abstract
Ionising radiation damages DNA directly and indirectly through increased production of reactive oxygen species. Although telomeres have been reported as indicators of radiosensitivity, their maintenance in response to occupational exposure to low radiation doses is still a matter of debate. In this work we aimed to investigate telomere length and structure in hospital workers occupationally exposed to X-rays and to relate these findings to oxidation of biomolecules and chromosome aberrations. Blood samples of exposed participants and matching controls were taken during periodical check-ups. Chromosome aberrations and telomere length and structure were analysed in peripheral blood lymphocytes using Q-FISH, whereas oxidative stress parameters [pro/antioxidant balance (PAB), lipid peroxidation, and 8-oxo-dG] were measured in plasma samples. Based on the CA findings we divided the exposed group into two subgroups, of which one had chromosome aberrations in the first division metaphases and the other did not. There was no significant difference in telomere length between any of the groups. However, both subgroups showed significantly higher rate of fragile telomeres and higher lipid peroxidation product and 8-oxo-dG levels than controls. The rate of fragile telomeres significantly correlated with plasma levels of 8-oxo-dG, which suggests that continuous exposure to low radiation doses induces oxidative base damage of guanine resulting in telomere fragility.
Influence of number of visitors and weather conditions on airborne particulate matter mass concentrations at the Plitvice Lakes National Park, Croatia during summer and autumn
Authors: Klaić Zvjezdana Bencetić , Leiva-Guzmán Manuel Andres , Brozinčević Andrijana 
Published: April 2022

Abstract
We investigated the influence of local meteorological conditions and number of visitors on ambient particulate matter (PM) mass concentrations and particle fraction ratios at the Plitvice Lakes National Park between July and October 2018. Outdoor mass concentrations of particles with aerodynamic diameters of less than 1, 2.5, and 10 μm (PM1, PM2.5, and PM10, respectively) and indoor PM1 were measured with two light-scattering laser photometers set up near the largest and most visited Kozjak Lake. Our findings suggest that the particles mainly originated from background sources, although some came from local anthropogenic activities. More specifically, increases in both indoor and outdoor mass concentrations coincided with the increase in the number of visitors. Indoor PM1 concentrations also increased with increase in outdoor air temperature, while outdoor PMs exhibited U-shaped dependence (i.e., concentrations increased only at higher outdoor air temperatures). This behaviour and the decrease in the PM1/PM2.5 ratio with higher temperatures suggests that the production and growth of particles is influenced by photochemical reactions. The obtained spectra also pointed to a daily but not to weekly periodicity of PM levels.
MATLAB educational tool for teaching Rayleigh random variable
Authors: Jovanovic Dolecek Gordana 
Published: April 2022

This paper presents the set of MATLAB demonstrations dedicated to teaching characteristics of Rayleigh random variable, which is important in wireless communication systems, radars, data science, and vibrations, among others. This educational tool is created as a complementary teaching tool in the online classes, during the COVID-19 pandemic, with the aim to help students to better understand the behavior and characteristics of this random variable. The Demo tool consists of three sets of demonstrations: Description, Parameters and Relation with Other Random Variables, Operations on Rayleigh Random Variable, and Generalization. The demo is made in MATLAB and utilizes all benefits provided by MATLAB, such as simplicity, good graphic environment, and interactive use, among others. Additionally, this demo is used with other demo programs, also made in MATLAB, in teaching/learning process of random variables. Students were very satisfied with this demo tool expressing that helped them understanding better the behavior, and characteristics of the Rayleigh random variable.
FAKTOR-FAKTOR YANG MEMPENGARUHI MASA STUDI DAN INDEKS PRESTASI KUMULATIF MAHASISWA DENGAN MODEL REGRESI LOGISTIK BINER BIVARIAT
Authors: Yelfera Siti Rani , YOZZA HAZMIRA , RAHMI HG IZZATI 
Published: April 2022

Mutu lulusan suatu perguruan tinggi biasanya sering diukur dari Indeks Prestasi dan masa studi mahasiswa. Pencapaian prestasi akademik mahasiswa dan masaÂ studinya dipengaruhi oleh berbagai faktor baik itu faktor internal maupun faktor eksternal. Pada penelitian ini dilakukan analisis faktor-faktor yang mempengaruhi masa studi dan Indeks Prestasi Kumulatif mahasiswa Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Andalas. Metode yang digunakan adalah regresi logistik biner bivariat. Hasil penelitian ini menunjukkan bahwa dari 15 variabel prediktor yang digunakan yaitu variabel jalur masuk, pilihan jurusan saat mendaftar Universitas Andalas, minat terhadap jurusan, bakat terhadap jurusan, tempat tinggal, biaya hidup perbulan, status penerima beasiswa, metode belajar, dukungan sosial, dukungan keluarga, keaktifan organisasi motivasi belajar, gaya belajar, kondisi kesehatan dan mental, dan fasilitas layanan akademik hanya ada dua variabel prediktor yang signififikan mempengaruhi masa studi dan Indeks Prestasi Kumulatif mahasiswa yaitu variabel jalur masuk dan motivasi belajar.Kata Kunci: masa studi, Indeks Prestasi Kumulatif, regresi logistik biner bivariat.Â
Construções metafóricas na narrativa da criança
Authors: Golembieski Gabriela 
Published: April 2022

Neste trabalho, busca-se descrever como se estabelecem as metáforas, concebidas como “transferências analógicas de denominações” (cfe. BENVENISTE, 2020), nos deslocamentos realizados pela criança na linguagem. O viés teórico-metodológico pauta-se na perspectiva enunciativa aquisicional (SILVA, 2009), a qual se baseia em princípios benvenistianos. Neste artigo, ilustra-se o tema com um dado de uma criança de 5 anos. O objetivo é descrever como se estabelecem as “transferências analógicas de denominações” nos deslocamentos realizados pela criança na linguagem. Compreende-se a metáfora como um arranjo de formas e sentidos que se estabelece no uso da língua pelo falante em determinada situação enunciativa e na relação intersubjetiva com o outro da enunciação. Nas vivências com o outro, na cultura da sociedade da qual faz parte, a criança vivencia o poder de significação advindo da propriedade simbólica da linguagem, o que lhe permite estabelecer analogias entre formas e sentidos da língua e mobilizar, no discurso, novos empregos para palavras e expressões da língua.
Pulmonary rehabilitation implementation in Northwest Nigeria: A qualitative study of the views of respiratory health-care professionals
Authors: Babaji Hafsat Umar , Sulaiman Surajo Kamilu , Shittu Aishat , Abubakar Yakubu , Mohammed Jibril 
Published: April 2022

Objectives:
Pulmonary rehabilitation (PR) service is a comprehensive program comprising both pharmacological and non-pharmacological (exercise training, counseling, nutritional, etc.) treatment options that have been proven to improve physical and psychological conditions of patients with chronic respiratory diseases (CRDs). Nevertheless, PR is non-existent in most parts of Africa. The objective of this study is to report on the views of respiratory health professionals (pulmonologists and allied health) regarding the implementation of PR in Northwest Nigeria.

Materials and Methods:
Using a qualitative descriptive design, a group of 11 purposively sampled respiratory health professionals working in tertiary hospitals in Northwest Nigeria was contacted to participate in the study. Semi-structured in-depth interviews were conducted with the participants. Information power was used to stop data collection. The data obtained were analyzed using thematic synthesis.

Results:
Six themes emerged from the interviews as follows: (i) Description of PR as a comprehensive life-saving intervention that involves exercises, education, self-care, and nutrition; (ii) absence of PR units; (iii) possession of knowledge of their roles; (iv) possession of basic knowledge of roles of other team members; (v) lack of specialized workforce; and (vi) lack of facilities and equipment. In general, the results of the study indicated that some respondents were more conversant with PR as an intervention in CRDs than others. Furthermore, the respondents had basic knowledge of the roles of other professionals in the delivery of PR. Finally, the major barriers to the utilization of PR services were poor awareness, lack of equipment, and workforce.

Conclusion:
There was a general lack of comprehensive PR services in the study area with respiratory health-care professionals demonstrating variable, but mostly good knowledge of PR.
Use of organic acid blends to control spread of salmonella heidelberg in broilers
Authors: Sausen Lourenço , Signor Mendes Angélica , Refatti Sikorski Rosana , Uliana Rosiane de Fátima , Ferreira Zago Cláudia Helena , Trevisan Lucas Renato , Evangelista Guimarães Bruno 
Published: April 2022

The objective was to evaluate an organic acid blend supplied via water and feed to control the spread of Salmonella Heidelberg in broilers from 1-31 days of age. The design was a complete randomized block with five treatments and five replicates, 25 experimental units (13 birds per unit, density of 13 birds/m2). 325 one day old female chicks were randomly arranged in five treatments: T1 - Negative Control (no acids + 0,5 ml of physiological solution in water); T2 - Positive control (no acids + 0,5 ml of Salmonella Heidelberg (1.206 CFU) in water); T3 - Via Acid water (inoculation of 0,5 ml of Salmonella Heidelberg (1.206 CFU) in water); T4 - Infeed Acid (inoculation of 0,5 ml of Salmonella Heidelberg (1.206 CFU) in feed); T5 - Acid via water and feed (inoculation of 0,5 ml of Salmonella Heidelberg (1.206 CFU)). The results were analyzed using Bayesian comparisons with 5% of significance and a priori beta distribution. Significant effects of treatments were found on feed conversion at 21, 28 and 31 days, treatment T3 had the best results. Regarding live weight, significant effects at 14, 21, 28 and 31 days were observed in T3, greater than others. The blend of organic acids has shown its numerical effectiveness in reducing the incidence of Salmonella Heidelberg among the treated groups in intestines pool at nine days, drag swab at 16 days and in wattle collection at 31 days. There were no significant differences between the treated groups and control groups.
The linkage between mercury-caused neuro- and genotoxicity via the inhibition of DNA repair machinery: fish brain model
Authors: Nedzvetsky V.S. , Gasso V.Y. , Herrmann B. , Novitskiy R.O. 
Published: April 2022

Heavy metals in model conditions as well as industrial pollution launch disturbances in neural cells of different animals and human beings. The neurotoxicity of mercury, which is one of the most toxic heavy metals, has been studied for several decades. However, its low doses chronic exposure effects for neural tissue cells are still poorly understood. Therefore, the basic molecular mechanisms of mercury should be clarified. The purpose of our research is to clarify the mechanism of mercury genotoxicity, the role of the DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in neural tissue cells, and the response to inorganic mercury-induced neurotoxicity. In our model, we used juvenile rainbow trout exposed to mercury chloride with a range of doses 9‑36 µg/L for 60 days to study the cytotoxicity of chronic exposure. We detected the reactive oxygen species (ROS) production as an index of oxidative stress and APE1 as a marker of cellular DNA damage response in a neural cell. The ROS level was measured by using the fluorometric method based on 2',7'-dichlorofluorescein diacetate reaction. The analyses of markers of the DNA repair (APE1) and apoptosis (B cell lymphoma-2 anti-apoptotic protein – Bcl-2) were carried out with western blotting. The mercury chloride chronic exposure induced statistically significant upregulation of the ROS production in the fish brain. Contrary, the mercury low doses stimulated the downregulation of APE1 expression in the brain tissue. Furthermore, mercury chronic exposure inhibited the expression of Bcl-2 in the animals treated with 18 and 36 µg/L mercury chloride. The harmful effect of mercury could be promoted by oxidative stress generation. The downregulation of APE1 expression could lead to a lack of DNA damage response efficacy and initiate the decline in neural cell functioning. Obtained data on the APE1 expression have shown that the neurotoxic effect of mercury could be mediated, at least partially, by the decline in cellular DNA damage response in the brain. The evaluation of decrease in DNA repair response via detection of the APE1 expression can be a prospective tool to reveal the deleterious effects of toxicants in terms of their neuro- and genotoxicity.
Remodeling of heart in patients with stable ischemic heart disease combined with chronic obstructive pulmonary disease as a basis for development of heart failure
Authors: Kniazieva O.V. , Potabashnii V.A. , Fesenko V.I. 
Published: April 2022

The aim of this study was to determine phenotypes of remodeling of heart and the status of systolic and diastolic function in patients with ischemic heart disease (IHD) combined with chronic obstructive pulmonary disease (COPD) with early symptoms and signs of heart failure (HF). We enrolled 108 males with stable IHD and spirometrically confirmed COPD which preceded the manifestations of IHD – the main group (group 1). As comparison groups 30 males with stable IHD (group 2) and 30 males with COPD (group 3) were examined. Control group included 30 males without IHD and respiratory diseases. All groups were comparable in age, groups 1 and 2 – in the duration of IHD, groups 1 and 3 – in the duration of COPD. The patients of the group 1 were divided into 3 subgroups: subgroup 1 – 45 patients with stable angina, subgroup 2 – 27 patients with postinfarction cardiosclerosis, subgroup 3 –36 patients with combination of stable IHD and arterial hypertension (AH) without history of myocardial infarction. The patients of group 1 had different phenotypes of heart remodeling, which depended on the clinical forms of IHD, the presence of concomitant AH, the severity of bronchial obstruction. The patients of subgroup 1 in 60.0% cases had concentric remodeling and concentric left ventricular hypertrophy (LVH), in 26.7% – normal LV geometry, in all these cases ejection fraction (EF) was preserved. Only in 13.3% of cases eccentric LVH with mildly reduced EF was found. 59.3% of patients in subgroup 2 had eccentric LVH, left atrium dilatation and 55.6% had reduced EF. All patients of subgroup 3 had concentric direction of LV remodeling. The phenotypes of HF with reduced and mildly reduced EF were accompanied by impaired LV diastolic function. In assessing the likelihood of HF with preserved EF the HFA-PEFF score showed better accuracy. Pulmonary hypertension had a mixed cause with predominance of postcapillar component.
Problems of regulating the quality of medical care in Ukraine and the main directions of their solution
Authors: Tolstanov K.O. , Krut A.G. , Dmitrenko I.A. , Gorachuk V.V. 
Published: April 2022

Improving the quality of health care remains problem of the day for world health systems.  Recognized quality management tools are used in Ukraine. However, a series of studies indicate the need for their improvement.. The aim of this work was to determine the features of the application of international instruments for regulating the quality of medical care and to substantiate the conceptual directions of their improvement in Ukraine. Materials and methods of research used: systemic approach; comparative analysis; bibliosemantic; conceptual modeling; scientific literature sources, including systematic reviews from the PubMed database; domestic legal documents. Main results: unlike international practices, professional activity of doctors is not licensed in Ukraine. The economic activity of health care institutions and individuals-entrepreneurs engaged in medical practice is subject to licensing. Аccreditation standards have not been revised since 2013. Domestic adaptation of clinical guidelines has been suspended for several years. Certification of quality management systems is administratively related to accreditation. All quality management tools are strictly regulated by the Ministry of Health, without the involvement of local governments, public patient organizations and health professionals. Conceptual directions of improvement of tools of quality regulation are offered: adoption of the law on professional licensing of doctors; creation of an independent accreditation agency; updating the content of accreditation standards, supplementing them with patient safety standards in accordance with international criteria; creation of methodological support for accreditation and certification; training of accreditation inspectors; introduction of tracer methodology in order to verify compliance with accreditation standards; resumption of adaptation of international clinical guidelines at the health sector.
ANALISIS DINAMIK MODEL PREDATOR-PREY DENGAN FUNGSI RESPON HOLLING TIPE II DAN EFEK KETAKUTAN
Authors: Amara Alicia Dhea , Savitri Dian 
Published: April 2022

Model prey-predator pada artikel ini mengikuti model modifikasi Leslie-Gower dengan fungsi respon tipe Holling II dan mempertimbangkan efek ketakutan. Efek ketakutan merupakan perilaku prey terhadap hadirnya predator yang dapat menurunkan laju pertumbuhan predator. Prosedur dalam penelitian meliputi, menentukan titik kesetimbangan, melakukan analisis kestabilan, dan mengkonfirmasi hasil analisis tersebut melalui simulasi numerik. Hasil analisis kesetimbangan dan kestabilan dari model diperoleh lima titik kesetimbangan yaitu, adalah tidak stabil, dan adalah stabil asimtotik serta dan adalah stabil dengan syarat. Hasil simulasi numerik terhadap solusi sistem yang memvariasikan parameter efek ketakutan menunjukkan kesesuaian dengan hasil analisis kestabilan. Parameter effek ketakutan pada prey dapat mempengaruhi kondisi prey dan berdampak berkurangnya populasi prey tersebut sehingga punah.
Kata Kunci: prey-predator, Leslie-Gower, efek ketakutan, Holling II
BILANGAN KETERHUBUNGAN PELANGI KUAT GRAF KUPU-KUPU, BENES, DAN TORUS
Authors: Fadlilah Dinda Anisa' Nur , Budayasa I Ketut 
Published: April 2022

Misalkan G graf terhubung. Pewarnaan-sisi graf G yakni fungsi W:E(G)→{1,2,…,k}= himpunan warna. Dalam hal ini, warna yang sama dapat diberikan pada dua sisi G yang terhubung pada titik yang sama. Graf G dengan Pewarnaan-sisi W disebut terhubung pelangi kuat jika untuk setiap dua titik u dan v di G ada lintasan pelangi terpendek dari titik u ke titik v. Lintasan pelangi adalah lintasan yang semua sisinya memiliki warna berbeda-beda. Minimum banyaknya warna yang dibutuhkan dalam mewarnai semua sisi G agar terhadap pewarnaan tersebut G terhubung pelangi kuat dinamakan bilangan keterhubungan pelangi kuat graf G dilambangkan dengan src(G). Di dalam artikel ini, akan ditentukan bilangan keterhubungan pelangi kuat graf kupu-kupu BF(n), Benes BB(n), dan torus T(m,n).
Kata Kunci: Pewarnaan sisi, Bilangan Keterhubungan Pelangi Kuat, Graf Kupu-kupu, Graf Benes, Graf Torus
Henna: Jenis dan Nilainya dalam Pernikahan Bugis di Bone
Authors: S Nurfadilah 
Published: April 2022

Penelitian ini bertujuan untuk mengkaji Henna yang digunakan pada pernikahan Bugis di Kabupaten Bone dan nilai-nilai yang terkandung dalam penggunaan Henna. Penelitian ini merupakan jenis penelitian deskriptif kualitatif dengan teknik studi survei. motif Henna yang digunakan pada pernikahan etnik bugis di kabupaten Bone meliputi motif kubah, mandala, sulur, teratai, lotus, peonhy, rose, daishy, heart dan padi. dengan jenis Henna natural, Henna instan, Henna white dan juga Henna gold. nilai-nilai yang terkandung dalam penggunaan Henna yaitu nilai simbolik motif kubah yang berarti permata kerajaan, mandala berarti pengabdian kepada ilahi, sulur berarti doa bagi pengantin lotus berarti kemurnian pikiran, peony berarti kehidupan bahagia, rose berarti kemurnian sebuah cinta, daisy berarti 2 perasaan yang tulus, heart berarti perasaan cinta, padi berarti tidak sombong terhadap kemampuannya.. Implikasi penelitian ini yaitu menjadi pembanding terhadap penggunaan dan makna Henna di tempat daerah lain.
PROBLEMATIKA PERNIKAHAN DINI DI DESA LARANGAN PERRENG KECAMATAN PRAGAAN KABUPATEN SUMENEP
Authors: Thayyib Moh 
Published: April 2022

The Abstract Every stages of individuals faced with a crisis which is a task of the development of the unique to be solved. The crisis is not a catastrophe but a turning point marked by the increased vulnerability and the potential of the person, the more individuals successfully resolve the crisis that it faces, the more healthy development of the individual. In developing countries marriage often is used as a sign for a for otherwise enter adulthood.” While the fact individuals who undergo early marriage instead there is no sign of maturity at all. It happened in our village Ban Perreng where children who are still of an early age who are married often do not signify what has been stated by Arnett in the book John W. Santrokch titled “Life-Span Development”. Keywords: Problems, Early Marriage.
MODEL KOMUNIKASI TASARO GK DALAM MEREPRESENTASIKAN KISAH NABI MUHAMMAD DAN KHULAFAU AL-RASYIDIN (STUDI ATAS SERIAL NOVEL MUHAMMAD KARYA TASARO GK)
Authors: Rifai Mohammad 
Published: April 2022

ABSTRAK Kisah atau perjalanan dakwah Nabi Muhammad dan Khulafãu al-Rasyidîn merupakan proses pembangunan hukum syari’at Islam yang sampai sekarang ini diikuti oleh semua umat islam. Maka dari itu, kisah ini sangat penting dikomunikasikan, baik secara lisan atau pun tulisan.Komunikasi merupakan aktivitas dasar manusia yang menjadi instrumen untuk menyampaikan perasaan-perasaan (emosi), pesan atau informasi yang ingin disampaikan. Dari itu, komunikasi memiliki peranan penting dalam kehidupan manusia, sehingga dari berbagai jenis komunikasi yang dilakukan manusia, lahirlah model komunikasi.Tasaro GK merupakan salah seorang yang mengkomunikasikan kisah Nabi Muhammad dan Khulafãu al-Rasyidîn melalui tulisan: novel. Penelitian ini bertujuan untuk merepresentasikan kisah Nabi Muhammad dan Khulafãu al-Rasyidîn dalam serial novel Muhammad karya Tasaro GK.Hasil penelitian menunjukkan bahwa ada beberapa model komunikasi yang digunakan Tasaro GK dalam merepresentasikan kisah Nabi Muhammad dan Khulafãu al-Rasyidîn yaitu komunikasi stimulus-respon, model komunikasi satu arah, model komunikasi dua arah, model komunikasi transaksi, model komunikasi ritual dan ekspresif, model komunikasi publisitas, serta model komunikasi resepsi.