bluuebunny/crossref_metadata_2025_split huggingface dataset:
Próba wykorzystania programu komputerowego QDA Miner do realizacji projektu badawczego „Cztery dyskursy o nowoczesności – modernizm peryferii na przykładzie Łodzi (XIX–XX wiek)”
Authors: Burski Jacek , Brzeziński Kamil 
Published: March 2022

Celem niniejszego artykułu jest przedstawienie podstawowych założeń metodologicznych i teoretycznych projektu „Cztery dyskursy o nowoczesności – modernizm peryferii na przykładzie Łodzi (XIX–XX wiek)” oraz zaprezentowanie możliwości wsparcia realizacji procesu badawczego poprzez wykorzystanie jednego z programów CAQDAS.
W artykule pokazana zostanie próba przedstawienia wstępnych wniosków z wykorzystania programu komputerowego QDA Miner, którego wydawcą jest firma Provalis, w analizie historycznych wypowiedzi prasowych. Zaprezentowane zostaną możliwości zastosowanego oprogramowania, jak i jego wpływ na przebieg całego procesu badawczego. Przedstawiony zostanie również sposób, w jaki wybór i wykorzystanie danego programu determinują decyzje dotyczące analizowanego materiału empirycznego, jego selekcję, kategoryzację i deskrypcję. Dodatkowym celem artykułu jest poszerzenie wiedzy metodologicznej i praktycznej z zakresu wykorzystywania wsparcia oprogramowania komputerowego w jakościowej analizie danych.
Artykuł został podzielony na kilka części, w pierwszej z nich przedstawiono krótki zarys historii wykorzystywania oprogramowania komputerowego do analiz jakościowych. Część druga poświęcona została podstawowym założeniom projektu badawczego „Cztery dyskursy o nowoczesności…”. Następnie omówiono sposób doboru oprogramowania odpowiadającego wymogom projektu, a w dalszej kolejności zaprezentowano pierwsze próby jego wykorzystania w ramach badania oraz jego wady i zalety.
The AKT Pathway and Satellite Cell Activation in Skeletal Muscle Mass Regulation
Authors: Sofiyanti Santi , Goenawan Hanna , Lesmana Ronny , Tarawan Vita Murniati 
Published: March 2022

Highlight:AKT or protein kinase B increase protein synthesis and control the degradation of proteins. Satellite cells was provided remarkable ability to regenerate skeletal muscle.Stimulation of protein synthesis is effective therapy to maintain muscle mass, prevent muscle wasting to reduce risk sarcopenia and improve quality of life in the elderly.Abstract:Muscles have an important role as a regulator of glucose and triglyceride metabolism. Some researches show the correlation between skeletal muscle mass and metabolic diseases, such as diabetes. Skeletal muscle mass decrease occurs due to chronic illness or physiological process of aging, thus increasing the risk of metabolic diseases as well as motion difficulty in the elderly. Skeletal muscle mass depends on balanced protein synthesis and degradation, controlled through a variety of signal transduction pathways including the AKT. AKT or protein kinase B increases protein synthesis through the mTOR and GSK3β and controls the degradation of proteins through FoxO transcription factors. Another factor that has an alleged role in the regulation of skeletal muscle is the satellite cells which provide remarkable ability to regenerate skeletal muscle. A comprehensive understanding of the biomolecular mechanism of muscle mass regulation is important to develop effective treatment or prevention of muscle atrophy in many cases, either caused by pathological conditions, such as chronic diseases, or the process of aging.
Profile of Skin Biopsy Patients in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Authors: Wandhita R.A. Astrid Putri , Sandhika Willy , Listiawan M. Yulianto 
Published: March 2022

Highlight:Profile of skin biopsy results which carried out the anatomical pathology examination was reviewed.The highest skin biopsy disease group case are erythropapulosquamous, infection, skin tumor, vesiculobullous, connective tissue disease, pigmentation disorders, and vasculitis Abstract:Skin biopsy is an important tool used by dermatologists in diagnostic determination. The correlation between clinical and histological features is needed in understanding pathogenesis and formulating the diagnosis of a skin disease with a greatly varied spectrum of histopathological results, while the observable clinical symptoms are highly limited. Skin diseases are still a serious problem worldwide, especially in Indonesia. Based on the Indonesian Health Profile in 2010, skin diseases ranked third out of 10 most diseases in outpatients in hospitals throughout Indonesia. This study was a review of the profile of skin biopsy results in Dr. Soetomo General Academic Hospital, Surabaya, Indonesia from 1 July 2014 to 31 July 2019, which were subjected to anatomic pathology examination. This study was an observational descriptive study using secondary data sources from the medical records at the Communication and Information Technology Installation (ICT) of Dr. Soetomo General Academic Hospital, Surabaya. Based on data searches, the total number of biopsy examinations performed was 1,368 cases. There were more female patients (50.3%) than males (49.7%). The most common skin disorder found was erythropapulosquamous disorder (30%), followed by infection (18%). Other cases consisted of skin tumor (15%), vesiculobullous (13%), connective tissue disease (7%), pigmentation disorders (5%), and vasculitis (5%). Diseases that could not be classified into 7 groups of the biopsy criteria were grouped separately in other diseases (7%).
Pre-Operative Hormonal Administration in Hypospadias Patients Undergoing Urethroplasty
Authors: Ramadhani Muhammad Zaniar , Renaldo Johan 
Published: March 2022

Highlight:The gold standard therapy of hypospadias is reconstructive surgery.Glans diameter and penile length are factors influencing urethroplasty outcomes.Many studies are being conducted to investigate various methods of increasing the size and diameter of the penis prior to the operation in order to reduce complications. Preoperative testosterone hormonal therapy is able to reduce overall complication and urethrocutaneous fistula in hypospadias patient undergoing urethroplasty.Abstract:The gold standard of treatment for hypospadias patients is reconstructive surgery. The result and post-operative complication of urethroplasty were affected by glans diameter and penile length. Pre-operative testosterone administration, both parenterally or topically, has become one of the main interests to increase the size and diameter of penis to minimize post-operative complications. However, there has not been enough evidence to justify this recommendation. Therefore, we aimed to perform a systematic review and meta-analysis to evaluate the role of pre-operative testosterone to prevent postoperative complications after urethroplasty in hypospadias patients. Online databases of Medline, Scopus and Embase were searched until October 2021 to identify RCT studies evaluating the effect of testosterone hormone therapy in reducing post-operative complication on hypospadias patient undergoing urethroplasty. Data analysis was performed using RevMan 5.4. A total of 4 RCTs were included in the analysis of this study with the total of 211 patients. Pre-operative testosterone hormonal therapy significantly reduced the overall complications group (OR=0.17; 95% CI=0.04, 0.77; p=0.02), post-operative urethrocutaneous fistula (OR=0.4, 95% CI=0.19, 0.83, p=0.01). Finally, there was no significant effect on the incidence of dehiscence and meatal stenosis with OR of 0.59, 95% CI=0.23, 1.54, p = 0.28, and 0.277; 95% CI=0.04, 1.65; p=0.16, respectively. Pre-operative testosterone hormonal therapy could reduce overall complication and urethrocutaneous fistula in hypospadias patients undergoing urethroplasty.
Kemampuan Pseudomonas Kelompok fluorescens dan Bacillus spp. Menghambat Perkembangan Fusarium spp. Penyebab Penyakit Layu Tanaman Terung
Authors: Syukur Abdullah , Aidawati Noor , Rosa Helda Orbani 
Published: March 2022

Tanaman terong (Solanum melongena L.) Permintaan buah terong yang semakin meningkat, tetapi ketersediaan buah terong rendah sehingga tidak dapat terpenuhi. Salah satu penyebab rendahnya produksi terong disebabkan adanya serangan penyakit layu pada tanaman terung disebabkan oleh Fusarium oxysporum. Gejala yang ditimbulkan berupa adanya daun yang layu, daun menguning dan jaringan akar dan batang berwarna coklat. Pengendalian yang sering dilakukan adalah dengan menggunakan pestisida (fungisida) yang dapat mengakibatkan pencemaran lingkungan. Satu pengendalian penyakit layu Fusarium spp. dengan mikroba antagonis. Penelitian ini dilakukan buat mengetahui kemampuan isolat rizobakteria Pseudomonas grup fluorescens(PF) dan Bacillus spp. dari bambu, cabai serta pakis menghambat perkembangan Fusarium spp. secara in vitro. Rancangan Acak Lengkap (RAL) dengan isolat Pseudomonas kelompok fluorescens dan Bacillus spp. masing- masing 4 perlakuan, kontrol. Pengujian daya hambat isolat Pseudomonas kelompok fluorescens dan Bacillus spp. dilakukan dengan metode tantang dan.secara in vitro. Pengamatan dilakukan terhadap persentase daya hambat bakteri rizosfer (DH) setelah inkubasi selama 7 hari. Semua isolat Pseudomonas grup fluorescens dan isolat Bacillus spp. Mempunyai daya hambat yang berbeda-beda pada cendawan Fusarium spp. Isolat Pseudomonas kelompok flourescens berasal dari akar bambu dari daerah Palem (KPBP) (81.95%) merupakan isolat yang mempunyai persentase daya hambat yang tertinggi dan Isolat Bacillus spp. berasal dari akar cabai dari daerah Guntung Manggis (BGTP1) (70%) merupakan isolat yang mempunyai persentase daya hambat yang tertinggi.
Diseminasi Pembuatan Pupuk Organik Cair dari Akar Bambu di Desa Srigading, Lampung Timur
Authors: Prasetyo Dedy , Wiharso Didin 
Published: March 2022

<p><em>Land degradation in the rice field is caused by the continuous use of synthetic agrochemicals and low input of organic fertilizers. Assistance and training for farmers are needed to utilize organic fertilizers as additional inputs in cultivation practices. Liquid organic fertilizer (LOB) can be a solution because the making process and application are easier. This dissemination aims to provide knowledge and practice of making LOB from local biological resources such as bamboo roots. The target of the activity are farmers in Srigading, Labuhan Maringgai, East Lampung. The activity was carried out using explanation method and the practice of making LOB from bamboo roots. This activity is carried out for 6 months covering surveys, preparation, delivering materials, practices, and monitoring. The activity was held on August 7, 2021 at the residence of Mr. Tugimin, with a total of 13 participants. The presentation of the material included the importance of soil organic matter for soil health, explanation about LOB, and continued the practice of making LOB. Based on the results of the pretest, the knowledge of farmers about negative impact of using synthetic agrochemicals and the importance of organic matter is still low, so that the explanation can increase farmers' knowledge as indicated by the posttest is increasing from 20% to 86%. Monitoring result showed that the LOB made has been successful with the characteristics like tape smell, but it is still not yet optimal. Farmers also expect follow-up activities for innovation on other organic fertilizers and biofertilizers.</em></p><p> </p>
Essex-Lopresti Lesions and Longitudinal Radioulnar Instability
Authors: Sheth Mihir , Mitchell Scott , Bell Bryce , Wu Chia 
Published: March 2022

» An Essex-Lopresti injury (ELI) is classically described as a radial head fracture with a concomitant interosseous ligament complex (IOC) injury. However, multiple injury patterns may be present, and an interosseous membrane (IOM) injury should be evaluated for in any axial load injury through the forearm. ELI may result in longitudinal radioulnar instability (LRUI).» Diagnosis of an IOC injury can be difficult. Evaluation begins with standard wrist and elbow radiographs and is supplemented with radiographs and intraoperative maneuvers to assess for proximal radial migration. Magnetic resonance imaging and ultrasonography may be useful in the acute setting, although indications and the clinical importance of the findings remain unclear.» Surgical management of an acute ELI is focused on restoration of radial length and temporary distal radioulnar joint (DRUJ) stabilization. Radial head excision in the acute setting should be approached with caution because proximal migration may not be present acutely but may develop over time. The indication for acute IOM repair and reconstruction remains unclear.» Surgical management of a chronic ELI is focused on restoration of radial length, wrist leveling, and treatment of degenerative changes (either at the radiocapitellar joint or the DRUJ). Reconstruction of the central band can restore forearm load transfer and produce favorable functional outcomes, but its indications continue to be debated.
Distal Hamstring Muscle Injuries
Authors: Matthews John R. , Sonnier John Hayden , Prodoehl John P. , Saucedo Samuel T. , Avendano John P. , Johns William , Freedman Kevin B. , Ciccotti Michael G. , Cohen Steven B. 
Published: March 2022

» Distal hamstring muscle injuries, although relatively uncommon, can potentially lead to substantial morbidity in athletes; prolonged rehabilitation times and high rates of reoccurrence have been documented.» Overall, magnetic resonance imaging is considered the “gold standard” for evaluation of hamstring injuries because it allows assessment for concomitant pathology and can clarify return-to-sport timelines.» Complete tears of the distal biceps femoris and semimembranosus muscles respond well to surgical repair, whereas complete tears of the distal semitendinosus can be successfully treated nonoperatively or with surgical resection.» Future research may be necessary to further optimize treatment of these injuries and to determine the efficacy of biologic adjuvant therapy.
A Multisectoral Approach to Advance Health Equity in Northern Arizona: County-level Leaders’ Perspectives on Health Equity
Authors: Jiménez Dulce J. , Sabo Samantha , Remiker Mark , Smith Melinda , Longorio Alexandra E. Samarron , Williamson Heather J. , Chief Carmenlita , Teufel-Shone Nicolette I. 
Published: March 2022

Abstract
Background: Multisectoral and public-private partnerships are critical in building the necessary infrastructure, policy, and political will to ameliorate health inequity. By focusing on health equity, researchers, practitioners, and decision-makers make explicit the systematic, avoidable, unfair, and unjust differences in health status across population groups sustained over time and generations, beyond the control of individuals. Health equity requires a collective process in shaping the health and wellbeing of the communities in which we live, learn, work, play, move, and grow.Methods: Data are drawn from the Southwest Health Equity Research Collaborative’s Regional Health Equity Survey (RHES). The RHES is a community-informed, cross-sectional online survey comprised of 31 quantitative and 17 qualitative questions. Generated to elicit an interdisciplinary body of knowledge and guide future multisectoral action for improving community health and well-being, the RHES targeted leaders representing five large rural northern Arizona counties and 13 distinct sectors. To explore, multisectoral leaders’ knowledge, attitudes, and actions to address the social, environmental, and economic conditions that produce and sustain health inequity were analyzed using a priori coding scheme and emergent coding with thematic analysis.Results: Although leaders were provided the definition and asked to describe the root causes of inequities, the majority of leaders described social determinants of health (SDoH). When leaders described root causes of health inequity, they articulated systemic factors affecting their communities and described discrimination and unequal allocation of power and resources. Most leaders described the SDoH of their communities by discussing compounding factors of poverty, transportation, and housing among others, that together exacerbate inequity. Leaders also identified specific strategies to address SDoH and advance health equity in their communities, ranging from providing direct services, to activating partnerships across organizations and sectors in advocacy for policy change.Conclusion: Our findings indicate that community leaders in the northern Arizona region acknowledge the importance of multisectoral partnerships and collaborations in improving health equity for the populations that they serve. However, a common understanding of health equity remains to be widely established, which is essential for conducting effective multisectoral work with the goal of advancing health equity.
Physical Exercise and Economic Burden Associated With Anxiety Symptoms in Pregnant Women During the COVID-19 Pandemic
Authors: Deng Jie , Hu Chun Hui , Ning Yu Xin , Xu Ping , Lu Chen , Wang Jia Qi , Sun Jun yi , Shou Shi cong , Chen Min , Duan Peng 
Published: March 2022

Abstract
Background: COVID-19 with high infectivity and high concealment has been widely spread around the world. This major public health event has caused anxiety among the public, including pregnant women. The aim of this study was to assess the incidence of anxiety symptoms in pregnant women during the COVID-19 pandemic and its influencing factors.Methods: Using an ongoing prospective pregnancy registry, we performed a single center cross-sectional analysis to investigate the overall prevalence of anxiety symptoms among pregnant women during the COVID-19 pandemic. Online questionnaires were used to collect information including sociodemographic data, physical activity and economic situations. The Zung Self-Rating Anxiety Scale (SAS) was used to assess anxiety symptoms. The univariate regression analysis was performed to detect factors potentially influencing anxiety symptoms among pregnant women. The multivariate regression analysis was also conducted to analyze the association of physical exercise and economic burden with anxiety symptoms by adjusting for other variables.Results: A total of 1,517 pregnant women entered the analysis. The study reported that 31.64% of the respondents had anxiety symptoms. Those with bank loans were at higher odds of suffering from anxiety symptoms compared to those without bank loans [(adjusted odds ratio (aOR) 1.494, 95% confidence interval (CI) 1.181~1.889]. Those who took 2,000~5,000 steps/day (aOR 0.825, 95% CI 0.603~0.875) and >5,000 steps/day (aOR 0.924, 95% CI 0.439~0.945) were at lower odds of suffering from anxiety symptoms compared to those who took <500 steps/day. Similarly, the adjusted odds ratios for anxiety symptoms was 0.750 (95% CI 0.663~0.790) and 0.800 (95% CI 0.226~0.889) lower in participants with exercise frequencies of 4-6, and ≥7 times/week, compared to those with a frequency of <2 times/week.Conclusions: Three in ten pregnant women experienced anxiety symptoms during the COVID-19 pandemic, and anxiety symptoms showed association with bank loans and physical exercise. To prevent anxiety of pregnant women, the promotion of healthy lifestyles, improvement of mental health services, and expansion of social support should be implemented during epidemics. In parallel, the integration of psycho-educational interventions with mental health services among public health centers is required to minimize anxiety symptoms in pregnancy women.
Psychometric properties of the mental health continuum-short form (MHC- SF) in Iranian adolescents
Authors: Afrashteh Majid Yousefi 
Published: March 2022

Abstract
Background
Psychological tests are necessary to assess and assess the mental state of individuals. Mental health is one of the important psychological indicators and is increasingly considered as having various aspects of well-being. The Mental Health Continuum-Short Form (MHC-SF) is a 14-item instrument that assesses mental health, focusing on emotional, psychological, and social well-being. The present study examined the psychometric properties of the Persian version of the MHC-SF among adolescents, focusing on its factor structure, internal consistency, construct validity, and gender measurement invariance.
Methods
The population of this study was Iranian adolescents between 11 and 18 years old who were enrolled in the seventh to twelfth grades. A convenience sample of 822 Adolescents from four large cities in the Iran (Tehran, Zanjan, Hamedan and Ghazvin) participated in the present study. Questionnaires were completed online. Statistical analyses to evaluate the factor structure, internal consistency, construct validity, gender and age factorial invariance were performed in SPSS and LISREL.
Results
The results of confirmatory factor analysis supported the 3-factor structure of MHC-SF (emotional, psychological, and social well-being). Reliability was confirmed by Cronbach's alpha method and composite reliability (> .7). Measurement invariance were confirmed among girls and boys. Convergent and divergent validity were also evaluated and confirmed by correlating the test score with similar and different tests.
Conclusion
This study examined and confirmed the psychometric properties of MHC-SF in the Iranian adolescent community. This instrument can be used in psychological research and diagnostic evaluations.
Clinical, Biochemical and Molecular Characterizations of Patients With Glutaric Aciduria Type 1 in Henan Province, China
Authors: Zhu Xinyun , Li Xiaole , Liu Suna , Ni Min , Guo Yaqing , Xu Yizhuo , Jia Liting , Li Linfei , Zhao Dehua 
Published: March 2022

Abstract
Background: Glutaric acidemia type 1 (GA1) is a rare organic acid metabolism disorder resulted from the deficiency of glutaryl-CoA dehydrogenase (GCDH). There are few studies on GA1 in China. This article is designed to investigate the clinical, biochemical and molecular characterizations of patients with GA1 in Henan province, in order to get further understanding of this disease .Results: The incidence of neonatal GA1 in Henan population was 1/172483. All patients had increased glutarylcarnitine (C5DC), glutaric acid (GA) and 3-hydroxyglutaric acid (3-OH-GA) levels. Twenty mutations were discovered in 14 patients. Four of them were novel: c.523G>A (p.G175S), c.1297G>C (p.A433P), c.467G>A (p.G156D) and c.1125T>G (p.C375W). The most common mutation was c.1064G>A (p.R355H), of which the allelic frequency was 17.86% (5/28), following by c.1109T>C (p.L370P), c.648G>A (p.S216S), c.395G>A (p.R132Q) and c.938G>A (p.R313Q), which had the same allelic frequency 7.14% (2/28). 84.6%(11/13) patients displayed abnormal brain MRI findings, of which cerebral dysplasia and arachnid/ependyma cysts(38.5%,5/13) were most commonly. Clinical features varied widely from asymptomatic to severe encephalopathy. Patients diagnosed by newborn screening had better outcome. A strong correlation was discovered among increasing disability in motor, speech and cognitive function. There were statistical significance differences in motor function(p=0.024) and speech function (p=0.008), but no statistical significance difference in cognitive function (p=0.106) between NBS group and non-NBS group.Conclusions: Our study provided comprehensive information about GA1 in Henan population, including morbidity, clinical, biochemical, molecular and outcome features. The novel variants expanded the GCDH variant spectra. This work emphasize that professional management of NBS programs and experienced genetic metabolic disease experts will be very important and urgent.