bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect Of Goal-Directed Haemodynamic Therapy On Short-Term Postoperative Complications In Patients With Extensive Burns: A Single-Centre Randomised Controlled Trial
Authors: Liang Bing , Cai Lianjie , Cao Yang , Huang Haoran , Zeng Jianhao , Peng Weilong , Zhang Yan 
Published: March 2022

Abstract
Background: To investigate the effect of goal-directed hemodynamic treatment on perfusion and short-term prognosis in patients undergoing early Tangential excision and skin grafting for extensive burns.Methods: Ninety-five patients with extensive burns undergoing early Tangential excision and skin grafting were randomly divided into a standard hemodynamic management group (control group) and a goal-directed therapy group (GDHT group), with the control group guided by conventional parameters and the GDHT group guided by stroke volume (SV) based on Vigileo. The primary outcomes were cardiac complications, pulmonary complications, neurological disease, acute kidney injury, and pain within 7 days postoperatively. Secondary outcomes included microcirculatory perfusion metrics: The central venous-arterial carbon dioxide partial pressure difference (Pcv-aCO2), and blood lactate (Lac). investigators assessing outcomes were blinded to group allocation.Results: When analysing 47 subjects in the GDHT group and 48 subjects in the control group, fewer patients in the GDHT group had postoperative pulmonary complications [pneumonia (2:9, P=0.027); oxygenation index <300 (3:8, P=0.041)] and controls were more likely to have atrial fibrillation (4:12, P=0.032) Renal and neurological complications did not differ between groups. Pcv-aCO2 and Lac were higher in the Con group after the intervention compared to the control group, and there was no difference between the two groups postoperatively. In this study, Pcv-aCO2 and Lac were Key influencing factors for pulmonary complications within 7 days postoperatively (Beta=0.197, P=0.000; Beta=0.147, P=0.000).Conclusion: SV-guided GDHT improves microcirculatory perfusion and has fewer short-term postoperative complications compared with standard hemodynamic therapy.Trial registration: NCT05221788 (03/02/2022)
Cost-effectiveness of an Intensive Upper Limb Rehabilitation Therapy for Children With Unilateral Cerebral Palsy: an Economic Evaluation of a Randomized Controlled Trial
Authors: David Michael C. , Higashi Hideki 
Published: March 2022

Abstract

BackgroundUnilateral cerebral palsy (UCP) is a major cause of childhood disability and a substantial economic burden. Intensive group-based therapy of either hybrid constraint-induced movement therapy (mCIMT) or bimanual therapy has been shown to be effective in improving specific domains of the Quality of Life (QoL) in children with this disability. However, there is a paucity of economic evaluation on its role as an adjunct to other therapies currently in use. This study aimed to address this paucity by evaluating whether an intensive group-based therapy model is cost-effective compared to individualized distributed standard care occupational therapy (SC).MethodsAn open-label parallel randomized controlled trial (RCT) and an embedded economic evaluation of intensive group-based hybrid-CIMT (combined mCIMT and bimanual therapy) were conducted. A total of 47 children were randomized to the hybrid-CIMT group (n=27) or the SC (n=20) group. Effectiveness was assessed using the Cerebral Palsy Quality of Life (Child) questionnaire across seven domains: 1) Social well-being and acceptance; 2) Functioning; 3) Participation and physical health; 4) Emotional well-being; 5) Access to services; 6) Pain; and 7) Impact of disability and family health. Using trial data, costs in Australian dollars (AUD) were assessed from a societal perspective. Non-parametric bootstrap analysis was used to quantify uncertainty intervals (UIs; around point estimates) accompanying incremental cost-effectiveness ratio estimates, the cost per unit of beneficial change in the quality of life.ResultsOnly for the domains of Pain (Incremental cost-effectiveness ratio: $273; 95% Uncertainty interval: $107 - $945) and to a lesser extent, Access to services ($1732; -$6448 - $8775) and the Impact of disability and family health ($1071; -$5718 - $4606), was hybrid-CIMT therapy found to be cost-effective when compared to SC. The probability that hybrid-CIMT was cost-effective for the Pain domain was estimated to be 0.50.ConclusionsHybrid-CIMT was not found to be cost-effective when compared to SC over a 13-week time horizon. In order to assess benefits and costs more fully, we recommend that future research utilize time horizons that extend sufficiently into the future. Irrespective of study duration, therapy comparisons should also consider acceptance, equity and feasibility.Trial registrationACTRN12609000912280. 21/10/2009, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12609000912280
Lay Persons Views On Current And Novel Methods Of Fertility Assessment And Supporting Conception: A Qualitative Study
Authors: Ng Ka Ying Bonnie , Glowacka Marta , Dennison Laura , Cheong Ying 
Published: March 2022

Abstract
Background: There is an ongoing trend towards delayed childbearing; 1 in 6 couples suffer from subfertility. For couples needing In-vitro fertilisation (IVF), one factor hindering advances in this area is lack of knowledge on in-vivo uterine conditions. A novel intrauterine sensor is currently under development to measure the intrauterine environment, as an innovative means of fertility assessment. Our study explored women’s views of current and novel methods of fertility assessment. Methods: A qualitative study was performed. A purposeful sampling method was used to recruit participants from public spaces within Southampton. Women were eligible if they were of reproductive age, planning a pregnancy, nulliparous and not undergoing clinical investigation/fertility treatment. Semi-structured interviews explored pregnancy planning, understanding and experiences of current/novel methods aiming to assess and improve fertility. Interviews were conducted until data saturation was reached (n=16). Inductive thematic analysis was performed. Results: The main factors influencing the decision of when to ‘start trying’ were education, financial stability and relationship status. Pregnancy was seen as a ‘physiological’ event without the need for intervention. Participants lacked knowledge of fertility indicators and had limited knowledge of available products to assess fertility/support conception. Although participants generally perceived a novel intrauterine sensor as acceptable and valuable, the main concerns centred around invasiveness, safety and discomfort.Conclusions: When developing a novel medical device, healthcare professionals should be aware of the user’s knowledge and views at each stage. A clear added benefit over conventional methods is needed and addressing invasiveness, safety, and comfort may improve the acceptability of the device.
Perinatal outcomes with a copper intrauterine device in situ after 28 weeks of gestation: a retrospective cohort study of sole center in southeast China.
Authors: Chen Xiuying , Zhao Baihui , Cao Lili , Zhao Peng , Huang Lili 
Published: March 2022

Abstract
Purpose: The purpose of this study was to investigate the pregnancy outcomes with a copper intrauterine device (IUD) in situ after 28 weeks of gestation and the association between pregnancy with copper IUDs and neonatal congenital malformations. Methods: This retrospective cohort study had compared the singleton pregnancies with the copper IUDs in situ and without IUDs after 28 gestational weeks in one delivery center of southeast China. The pregnant outcomes as preterm birth, premature rupture of membranes, infections and neonatal congenital malformations were observed and compared. The statistical analysis was carried out using R (version 4.0.4; R Development Core Team) statistical software. Results: A total of 147 pregnant women were included in our study, 73 with copper IUDs in situ were categorized into case group and 74 without IUDs during pregnancy into control group. In case group, the rates of premature rupture of membranes (38.36%) and spontaneous preterm birth (23.29%) were significantly high compared to control group. Women of elder age (≥35 years) in case group were more likely to experience premature rupture of membranes. The rates of neonatal congenital malformation were 10.96% (8/73) in case group and 1.35% (1/74) in control group respectively with no statistically significant difference. Conclusion: We had found that a copper IUD with pregnancy in situ increased the risk of premature rupture of membranes and spontaneous preterm birth after 28 gestation weeks, nearly one fourth of those women were encountered spontaneous preterm birth, but not increased risk of neonatal congenital malformations.
A Survey on Face Recognition Based on Deep Neural Networks
Authors: Norouzi Mohsen , arshaghi ali 
Published: March 2022

Abstract
Face recognition is one of the most important and challenging issues in computer vision and image processing. About half a century ago, since the first face recognition system was introduced, facial recognition has become one of the most important issues in industry and academia. In recent years, with the developing of computers throughput and developments of a new generation of hierarchical learning algorithms called deep learning, much attention has been devoted to solving learning problems by deep learning algorithms. Deep neural networks perform feature learning instead of feature extraction which by this strategy they are much useful for image processing and computer vision problems. Deep neural network through feature learning perform data representation well and have gained many successes in learning and complex problems, many studies have been done on the application of deep neural networks to face recognition and many successes has been achieved. In this study we examine the neural network based methods used for face recognition such as multilayer perceptrons, restricted Boltzmann machine and auto encoders. Most of our study devoted to convolutional neural network as one of the most successful deep learning algorithms. At the end we have examined the results of the encountered methods on ORL, AR, YALE, FERET datasets and show deep neural network has gained high recognition rate in comparing with benchmark methods.
An Investigation into Entrepreneurial Intentions in Caribbean Small Island Developing States
Authors: Mohan Preeya 
Published: March 2022

Abstract
This paper explored entrepreneurial intentions in the Caribbean adult population using a social cognitive approach. It used the Global Entrepreneurship Monitor (GEM) Adult Population Survey (APS), which includes questions about entrepreneurial intentions of potential business owners and entrepreneurial perceptions namely individual, entrepreneurial opportunities, and socio-cultural, along with demographic and socio-economic variables. The effect of perceptions along with socio-economic control variables on entrepreneurial intentions was investigated using probit regression models. The results confirm that even after controlling for demographic and socio-economic and country fixed effects, social cognitive perceptions were indeed relevant in explaining entrepreneurial intentions in the region. This study therefore provides insights into understanding entrepreneurship in particular the decision to form a new business through the individual’s perceptions and intentions.
Innovation and Entrepreneurship: Attitudes and intentions of undergraduates in a developing country
Authors: Abu-Rumman Ayman , Shraah Ata Al , AlSha’ar Hamzeh , Alqhaiwi Laith A. 
Published: March 2022

Abstract
Purpose – This study aimed to explore the relationship between entrepreneurial attitudes, innovation, and entrepreneurial intentions amongst university students studying in Jordan. Design/methodology/approach – The study employed a quantitative methodological approach using an e-questionnaire survey and structural equation modelling analysis, underpinned by the theory of planned behaviour. The study collected data from 878 final semester students of business studies from 10 Jordanian universities. Findings – The study outcomes confirmed that attitude to become entrepreneurial and innovativeness lead to entrepreneurial intentions, and that this is supported through the application of appropriate teaching methodology. Originality/value – Throughout the world policy makers and governments are trying to strengthen entrepreneurship. In order to achieve this, there is a need to develop entrepreneurial intentions amongst those leaving education. This study was conducted in a developing country which is generally considered to be a haven for small and medium enterprises (SMEs) but yet the rate of entrepreneurship is still low and limited research exists to understand this phenomenon better. This study therefore aimed to add to the body of evidence in this field and present an understanding of the causal relationship between innovativeness, attitude towards entrepreneurship, and entrepreneurial intentions of Jordanian undergraduates.
Measuring Financial Satisfaction of Indonesian Young Adults: A SEM-PLS Analysis
Authors: Nabila Farizka Shafa , Fakhri Mahendra , PRADANA MAHIR , Kartawinata Budi Rustandi , Silvianita Anita 
Published: March 2022

Abstract
The Indonesian population, especially Generation Z, tend to have difficulties in managing their finances both now and in the future. This situation is caused by the lack of knowledge about financial investment. This study aims to determine the financial level of Generation Z. This study used a questionnaire with 100 respondents. The independent variable consists of financial attitudes, the intervention variable is financial management and the dependent variable in this study is financial satisfaction. The research method used is a quantitative method with a Likert scale as a measurement. The data analysis method used in this study is Structural Equation Modeling (SEM) and processed using SmartPLS. Based on the results of the hypothesis that the financial attitude variable on financial satisfaction mediated by financial management has a t statistic of 4.268 > 1.96, it means that the financial attitude variable has a positive and significant effect on financial satisfaction mediated by financial management.
Prevalence of Dental Caries and Relation with Nutritional Status Among School-Age Children in Resource Limited Setting of Southern Ethiopia
Authors: Bassa Selamawit , Workie Shimelash Bitew , Kassa Yibeltal , Worku Dawit 
Published: March 2022

Abstract
Background
Dental caries is a major public health problem globally and a widespread non -communicable disease. Dental caries is more prevalent in school-age children however there are few studies for relation of dental caries with nutritional status. Thus, this is aimed to determine the relation of dental caries with nutritional status among school-age children at Areka town Woliata zone from February 03 - February 22, 2020.
Methodology
: A community-based cross sectional study was conducted on systematic randomly selected 761 school-age children (6-12years) of Areka town. Data were collected by face-to-face interviewer-administered questionnaire and clinical assessment of dental caries. Data were entered into Epi data 3.2.1 and exported to SPSS 20 for further analysis. Bivariate and multiple logistic regression analyses were used to identify the association of dependent and independent variables. P-value < 0.05 was considered to declare a result as statistically significant.
Results
Prevalence of dental caries among school-age children was 15.6% with (95% CI, 13.0-18.5%). Nutritional status were 4.3% (95% CI, 2.9–5.8%) of children were underweight and 14.2% (95% CI, 11.7–16.6%) were overweight. The relationship between dental caries with nutritional status was not statistically significant with a p-value (p = 0.32). Factors associated with dental caries were educational status of a mother AOR 3.14, (95% CI, 1.03–9.56), not cleaning teeth AOR 7.70, (95% CI, 4.00-14.85), sugared coffee drinking AOR 3.22, (95% CI, 1.68–6.18.0), sweet food consumption AOR 4.19,(95% CI, 1.76–9.96) and non-consuming milk AOR 5.66,( 95% CI, 1.49–21.49).
Conclusion and recommendation:
Dental caries were low compared to WHO oral health reports of school-age children. Tooth cleaning habit, parental education, sweet food consumption and milk consumption are associated factors. Therefore, Behavioral intervention on dental hygiene and dietary practices are mandatory for school-age children.
Allogeneic Tendon Ball Tamponade With The Proximal Joint Surface Of Trapezium Preservation For Treatment Of The First Carpometacarpal Joint Arthritis: A Retrospective Study
Authors: Cai Xiao-Ming , Lu Chen-Lin , Li Jun-Jie , Yuan Hui-Zong , Yin Jie , Wang Xin 
Published: March 2022

Abstract
Background: The purpose of this study was to analyze the clinical efficacy of allogeneic tendon ball tamponade with the proximal joint surface of trapezium preservation for the treatment of patients with first carpometacarpal arthritis in patients in Eaton stage Ⅱ and Ⅲ.Methods: Data of 16 patients with first carpometacarpal arthritis who were treated with allogeneic tendon ball tamponade with the proximal joint surface of trapezium preservation from April 2016 to June 2021 were retrospectively analyzed. The subsidence rate of the first carpometacarpal joint was evaluated based on the height of the joint space and its index according to three-dimensional computed tomography (3D-CT). Visual analogue scale (VAS) score, disabilities of the arm, shoulder, and hand (DASH) score, grip strength and pinch force pre- and post-operatively were analyzed. The data were analyzed by t-test or one-way analysis of variance (ANOVA) followed by Tukey’s post hoc test for multiple comparisons. Results: All participants were followed up for at least 8 months. After the surgery, the VAS and DASH scores were significantly lower than those before surgery. The pinch strength and grip strength significantly increased. No significant difference was found in the carpometacarpal height index at the final follow-up, indicating that the first metacarpal had no obvious collapse after surgery. Conclusion: Allogeneic tendon tamponade with the proximal joint surface of trapezium preservation is effective for the first carpometacarpal joint arthritis in patients with Eaton stages Ⅱ and Ⅲ. The therapeutic effect of this modified operation was satisfactory for alleviating pain and reducing the collapse rate of the first metacarpal.
Initial experiences of prehospital blood product transfusions between 2016-2020 in Päijät-Häme hospital district, Finland
Authors: Yliharju Heidi , Jama Timo , Nordquist Hilla 
Published: March 2022

Abstract
Background: Treating hemorrhaging patients with prehospital blood product transfusions (PHBT) narrows transfusion delays and potentially benefits the patient. We describe our initial experiences of PHBT in a ground-based emergency medical service (EMS), where the transfusion protocol covers both traumatic and nontraumatic hemorrhaging patients.Methods: A retrospective analysis was performed on the records of all the patients receiving red blood cells, freeze-dried plasma, or both during prehospital care from September 2016 to December 2020. The delays of PHBT and the effects on patients’ vital signs were analyzed and reported as the median and interquartile range (IQR) and analyzed using a two-sided t-test of ANOVA. Results: 65 patients received prehospital blood product transfusions (PHBT), 29 (45%) were non-traumatic, and 36 (55%) traumatic. The main two reasons for PHBT were blunt trauma (n=30, 46%) and gastrointestinal hemorrhage (n=20, 31%). The median delay from the emergency call to the start of PHBT was 54 minutes (IQR 38), and the transfusion began on a median of 61 minutes (IQR 42) before arrival at the hospital. The median systolic blood pressure improved from a median 76.5 mmHg (IQR 36.5) before transfusion to a median of 116.60 mmHg (IQR 26.5) (p<0.001) on arrival to the hospital. No transfusion-related severe adverse events were noted.Conclusions: Starting PHBT in ground-based EMS is a feasible and viable option. The PHBT began significantly earlier than it would have started on arrival to the hospital, and it seems to be safe and improve patients’ physiology. Trial registration: D/2603/07.01.04.05/2019
High Frequency Ultrasound to Assess Facial Skin Thickness with Gender, Age and BMI in Healthy Adults
Authors: Meng Ying , Feng Lan , Shan Jiali , Yuan Zixu , Jin Lin 
Published: March 2022

Abstract
Background
With the high frequency of ultrasonic instruments, high frequency ultrasound plays a more and more important role in normal skin measurement, skin disease diagnosis and cosmetic medicine. The study aimed to estimate the skin epidermis and dermis thickness on eight different sites of the face in healthy adults with high frequency ultrasound, and evaluate the correlation with age and BMI.
Methods
In this study, we performed a facial skin ultrasound on 118 volunteers using high frequency ultrasound. Their epidermis and dermis thickness of forehead, glabella, temple, eyelid, nasal dorsum, zygoma, submaxilla and neck were measured. The correlation of the epidermis and dermis thickness with age and BMI was analyzed by linear correlation analysis.
Results
The epidermis and dermis thickness in males were statistically significantly higher than female (P༜0.05), except the thickness of zygomatic epidermis and neck dermis. The dermis thickness on zygoma and submaxilla of female in young age group was statistically higher than middle age and old group respectively (P༜0.05). Overall, with the increase of age, the thickness of female facial skin decreased, mainly in the forehead, glabella, zygoma and submaxill dermis thickness. In females, the epidermis and the dermis thickness of neck were correlated with BMI (r = 0.392, 0.241, P༜0.05, respectively). However, in males, the epidermis and dermis thickness was correlated with age only in zygoma dermis (r=-0.327, P༜0.05), while there was no correlation between the epidermis and dermis thickness and BMI.
Conclusions
Gender, age and BMI had significant effect on the epidermis and dermis thickness on different sites of the face.