bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geoeconomics in a Changing Global Order
Authors: Babić Milan , Dixon Adam D. , Liu Imogen T. 
Published: October 2022

AbstractThis introductory chapter presents an overview and summary of the focus of this edited volume. We first discuss the contribution of the chapters to a more nuanced and novel way of studying geoeconomic dynamics from an IPE perspective as going beyond the classical geopolitical focus on conflict, state-centrism, and security issues. We then embed the volume in broader changes of globalization from the neoliberal era into a more confrontative phase since 2016. The third part of the introduction then interrogates the role of the EU in this changing global order and makes the case for studying this sidelined actor in contemporary discussions about geoeconomics. The fourth and last part introduces the different chapters in detail and lays out the plan of this book.
Balancing Dependence: The Quest for Autonomy and the Rise of Corporate Geoeconomics
Authors: Choer Moraes Henrique , Wigell Mikael 
Published: October 2022

AbstractThe acceleration of great-power competition is leading most major powers to become increasingly concerned about the security risks that economic interdependence poses for state autonomy. This tendency can be seen in the EU’s efforts to develop its ‘open strategic autonomy’, the United States’ ‘reshoring’ of supply chains and technological ‘decoupling’, as well as China’s ‘Made in China’- strategy. In order to make sense of these transformations, this chapter introduces the concept of ‘balancing dependence’, by which we refer to state policies that seek to reduce economic dependencies on foreign actors, both public and private. The chapter describes how such geoeconomic balancing by major economies triggers a reaction by other economies in such a way that challenges the largely market-oriented rationale of the (neo)liberal order prevailing over the course of the last three decades. Yet, in an interdependent global economy, it is expected that companies will try to influence the impact of governments’ actions over their businesses, either to discourage geoeconomic balancing or to benefit from it. Thus, the chapter also puts forward the concept of ‘corporate geoeconomics’, which describes how firms are trying to preserve a measure of autonomy in an economic environment marked by increased state (geoeconomic) intervention.
Teilhabe und soziale Gerechtigkeit: normative Anforderungen im Kontext von Behinderung
Authors: Blaha Kathrin 
Published: October 2022

ZusammenfassungDieser Beitrag begreift sich als Versuch, mithilfe philosophischer und sozialwissenschaftlicher Überlegungen die normativen Anforderungen im Kontext von Behinderung zu skizzieren, die sich aus einer kritischen Reflexion des Zusammenhangs von Teilhabe und sozialer Gerechtigkeit ergeben. Hintergrund ist, dass Theorien der Gerechtigkeit Schwierigkeiten haben, Menschen mit kognitiven und schweren Beeinträchtigungen zu inkludieren. Ziel des Beitrages ist ein Plädoyer für eine Berücksichtigung menschlicher Verletzlichkeit, die auch einen kritischen Blick auf Teilhabeanforderungen erlaubt.
Giant gravitons, Harish-Chandra integrals, and BPS states in symplectic and orthogonal $$ \mathcal{N} $$ = 4 SYM
Authors: Holguin Adolfo , Wang Shannon 
Published: October 2022

Abstract
We find generating functions for half BPS correlators in $$ \mathcal{N} $$
N
= 4 SYM theories with gauge groups Sp(2N), SO(2N + 1), and SO(2N) by computing the norms of a class of BPS coherent states. These coherent states are built from operators involving Harish-Chandra integrals. Such operators have an interpretation as localized giant gravitons in the bulk of anti-de-Sitter space. This extends the analysis of [1] to Sp(2N), SO(2N + 1), and SO(2N) gauge theories. We show that we may use ordinary Schur functions as a basis for the sector of states with no cross-caps in these theories. This is consistent with the construction of these theories as orientifold projections of an SU(2N) theory. We make note of some relations between the symmetric functions that appear in the expansion of these coherent states and symplectic Schur functions. We also comment on some connections to Schubert calculus and Gromov-Witten invariants, which suggest that the Harish-Chandra integral may be extended to such problems.
Distale Bizepssehnenruptur
Authors: Engler Cedric , Grezda Kushtrim , Rosso Claudio 
Published: October 2022

ZusammenfassungDie Ruptur der distalen Bizepssehne tritt am häufigsten bei Männern im mittleren Alter auf (30 bis 50 Jahre). Der typische Mechanismus ist die exzentrische Belastung in strecknaher Ellbogenstellung in Supination, wobei diese Verletzung mit Kraftsport und körperlich belastender Tätigkeit assoziiert ist. Epidemiologische Daten weisen auf eine Zunahme von distalen Bizepsrupturen in den letzten Jahrzehnten hin. Risikofaktoren wie die Verwendung anaboler Steroide, Kraftsport und Nikotinabusus zeigen einen Zusammenhang mit der Verletzung. Bei reduziertem Patientenanspruch oder relevanten Komorbiditäten ist auch unter einer konservativen Behandlung ein gutes funktionelles Ergebnis mit subjektiv guter Patientenzufriedenheit zu erreichen, allerdings unter zu erwartender relevanter Kraftminderung in Flexion (20 %) und Supination (40 %). Durch eine operative Refixation lässt sich das beste funktionelle Resultat erzielen, allerdings einhergehend mit einem nicht unerheblichen Komplikationsrisiko.
Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A
Authors: Hassan Reham , González Daniela , Hobloss Zaynab , Brackhagen Lisa , Myllys Maiju , Friebel Adrian , Seddek Abdel-latif , Marchan Rosemarie , Cramer Benedikt , Humpf Hans-Ulrich , Hoehme Stefan , Degen Gisela H. , Hengstler Jan G. , Ghallab Ahmed 
Published: October 2022

AbstractThe mycotoxin ochratoxin A (OTA) is a contaminant in food that causes nephrotoxicity and to a minor degree hepatotoxicity. Recently, we observed that OTA induces liver damage preferentially to the cytochrome P450 (CYP)-expressing pericentral lobular zone, similar to hepatotoxic substances known to be metabolically toxified by CYP, such as acetaminophen or carbon tetrachloride. To investigate whether CYP influences OTA toxicity, we used a single dose of OTA (7.5 mg/kg; intravenous) with and without pre-treatment with the pan CYP-inhibitor 1-aminobenzotriazole (ABT) 2 h before OTA administration. Blood, urine, as well as liver and kidney tissue samples were collected 24 h after OTA administration for biochemical and histopathological analyses. Inhibition of CYPs by ABT strongly increased the nephro- and hepatotoxicity of OTA. The urinary kidney damage biomarkers kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL) were increased > 126-fold and > 20-fold, respectively, in mice treated with ABT and OTA compared to those receiving OTA alone. The blood biomarkers of liver damage, alanine transaminase (ALT) and aspartate transaminase (AST) both increased > 21- and 30-fold, respectively, when OTA was administered to ABT pre-treated mice compared to the effect of OTA alone. Histological analysis of the liver revealed a pericentral lobular damage induced by OTA despite CYP-inhibition by ABT. Administration of ABT alone caused no hepato- or nephrotoxicity. Overall, the results presented are compatible with a scenario where CYPs mediate the detoxification of OTA, yet the mechanisms responsible for the pericental liver damage pattern still remain to be elucidated.
Speicheldrüsenkarzinome – ein aktueller Überblick
Authors: Rupp Niels J. , Freiberger Sandra N. 
Published: October 2022

ZusammenfassungIn den letzten Jahren hat die Charakterisierung der Speicheldrüsenkarzinome einen großen Wandel durchlebt. Morphologisch definierte Entitäten konnten zu einem Großteil auch molekular mit einem oftmals distinkten Genotyp charakterisiert werden. Der erste Teil des Artikels gibt einen Überblick über die Fortschritte der molekularen Charakteristiken des Mukoepidermoidkarzinoms, adenoid-zystischen Karzinoms, Azinuszellkarzinoms, des sekretorischen und intraduktalen Karzinoms sowie des hyalinisierenden klarzelligen Karzinoms. Der molekulare Genotyp kann dabei insbesondere bei der Klassifizierung ungewöhnlicher morphologischer Varianten von großem Nutzen sein. Rekurrente NTRK- oder RET-Genfusionen können dabei nicht nur als diagnostisches Hilfsmittel, sondern auch für eine potenzielle gezielte Therapie genutzt werden.
Correction to: Urbanization Impact on Regional Climate and Extreme Weather: Current Understanding, Uncertainties, and Future Research Directions
Authors: Qian Yun , Chakraborty T. C. , Li Jianfeng , Li Dan , He Cenlin , Sarangi Chandan , Chen Fei , Yang Xuchao , Leung L. Ruby 
Published: October 2022

The article “Urbanization Impact on Regional Climate and Extreme Weather: Current Understanding, Uncertainties, and Future Research Directions”, written by Yun QIAN, TC CHAKRABORTY, Jianfeng LI, Dan LI, Cenlin HE, Chandan SARANGI, Fei CHEN, Xuchao YANG, and L. Ruby LEUNG was originally published electronically on the publisher’s internet portal on 25 of January 2022 with open access. With the author(s)’ decision, the copyright of the article changed from © The Author(s) 2022 to © Battelle Memorial Institute [2022].The original article has been corrected.
Feministische Perspektiven in der deutschsprachigen Medizinethik: eine Bestandsaufnahme und drei Thesen
Authors: Faissner Mirjam , Hartmann Kris Vera , Marcinski-Michel Isabella , Müller Regina , Weßel Merle 
Published: October 2022

ZusammenfassungIm internationalen Diskurs sind feministische Perspektiven auf die Medizinethik bereits etabliert. Demgegenüber scheinen diese bislang nur vereinzelt in den deutschsprachigen medizinethischen Diskurs eingebracht zu werden. In diesem Artikel untersuchen wir, welche feministischen Perspektiven im deutschsprachigen medizinethischen Diskurs vertreten sind, und schlagen weitere Ansätze für eine feministische Medizinethik vor.Zu diesem Zweck zeichnen wir mittels einer systematisierten Literaturrecherche feministische Perspektiven im deutschsprachigen medizinethischen Diskurs seit der Etablierung der Medizinethik als eigenständiger institutionalisierter Disziplin nach. Wir analysieren, welche Themen bereits innerhalb der Medizinethik aus einer feministischen Perspektive untersucht worden sind, und identifizieren Leerstellen. Basierend auf der Literaturrecherche, unseren eigenen Vorarbeiten sowie der Zusammenarbeit in der Arbeitsgruppe in der Akademie für Ethik in der Medizin „Feministische Perspektiven in der Bio- und Medizinethik“ stellen wir drei Thesen vor, die aus unserer Sicht einer Weiterentwicklung des deutschsprachigen medizinethischen Diskurses dienen können. Die erste These bezieht sich auf die Ziele feministischer Medizinethiken und besagt, dass diese (epistemische) Gerechtigkeit anstreben. Die zweite These stellt zentrale Eigenschaften von feministischen Medizinethiken als kritisch und kontext-sensibel heraus. In der dritten These diskutieren wir Intersektionalität und Postkolonialismus als theoretische Ansätze, die zu einer epistemisch gerechten, kritischen und kontext-sensiblen Medizinethik beitragen können. Wir argumentieren, dass feministische Perspektiven grundständig verankert werden sollten. Der Artikel schließt mit einem Ausblick auf die Arbeit der im letzten Jahr gegründeten Arbeitsgruppe in der Akademie für Ethik in der Medizin „Feministische Perspektiven in der Bio- und Medizinethik“.
Error bounds, facial residual functions and applications to the exponential cone
Authors: Lindstrom Scott B. , Lourenço Bruno F. , Pong Ting Kei 
Published: October 2022

AbstractWe construct a general framework for deriving error bounds for conic feasibility problems. In particular, our approach allows one to work with cones that fail to be amenable or even to have computable projections, two previously challenging barriers. For the purpose, we first show how error bounds may be constructed using objects calledone-step facial residual functions. Then, we develop several tools to compute these facial residual functions even in the absence of closed form expressions for the projections onto the cones. We demonstrate the use and power of our results by computing tight error bounds for the exponential cone feasibility problem. Interestingly, we discover a natural example for which the tightest error bound is related to the Boltzmann–Shannon entropy. We were also able to produce an example of sets for which a Hölderian error bound holds but the supremum of the set of admissible exponents is not itself an admissible exponent.
Multi-level personalization of neuromusculoskeletal models to estimate physiologically plausible knee joint contact forces in children
Authors: Davico Giorgio , Lloyd David G. , Carty Christopher P. , Killen Bryce A. , Devaprakash Daniel , Pizzolato Claudio 
Published: October 2022

AbstractNeuromusculoskeletal models are a powerful tool to investigate the internal biomechanics of an individual. However, commonly used neuromusculoskeletal models are generated via linear scaling of generic templates derived from elderly adult anatomies and poorly represent a child, let alone children with a neuromuscular disorder whose musculoskeletal structures and muscle activation patterns are profoundly altered. Model personalization can capture abnormalities and appropriately describe the underlying (altered) biomechanics of an individual. In this work, we explored the effect of six different levels of neuromusculoskeletal model personalization on estimates of muscle forces and knee joint contact forces to tease out the importance of model personalization for normal and abnormal musculoskeletal structures and muscle activation patterns. For six children, with and without cerebral palsy, generic scaled models were developed and progressively personalized by (1) tuning and calibrating musculotendon units’ parameters, (2) implementing an electromyogram-assisted approach to synthesize muscle activations, and (3) replacing generic anatomies with image-based bony geometries, and physiologically and physically plausible muscle kinematics. Biomechanical simulations of gait were performed in the OpenSim and CEINMS software on ten overground walking trials per participant. A mixed-ANOVA test, with Bonferroni corrections, was conducted to compare all models’ estimates. The model with the highest level of personalization produced the most physiologically plausible estimates. Model personalization is crucial to produce physiologically plausible estimates of internal biomechanical quantities. In particular, personalization of musculoskeletal anatomy and muscle activation patterns had the largest effect overall. Increased research efforts are needed to ease the creation of personalized neuromusculoskeletal models.
Modeling difficulties in creating conceptual data models
Authors: Rosenthal Kristina , Strecker Stefan , Snoeck Monique 
Published: October 2022

AbstractConceptual modeling is a learning task essential to students of computer science, software engineering and related programs. Construed as a complex task, surprisingly little is known about the actual act of conceptual modeling, and about modeling difficulties learners experience. Combining complementary modes of observation of learners’ modeling processes, we study modeling difficulties encountered while performing a data modeling task. Using the concept of cognitive breakdown, we analyze audiovisual protocols of the individual modelers’ modeling processes, recordings of their interactions with the employed modeling software tool and survey data of modelers about their perception of encountered modeling difficulties. In an exploratory study and a follow-up study, we identify eight types of modeling difficulties related to modeling entity types, generalization hierarchies, relationship types, attributes and cardinalities. The identified types of modeling difficulties contribute to a better and more complete understanding of data modeling processes intended to inform design science research on modeling assistance for data modelers at different stages of their learning and mastering of conceptual data modeling.
Sensory brain activation during rectal balloon distention: a pilot study in healthy volunteers to assess safety and feasibility at 1.5T
Authors: Assmann Roman , Rutten Sanne , van den Hurk Job , Assmann Sadé Laurèl , Janssen Paul , Bouvy Nicole , Melenhorst Jarno , Breukink Stephanie 
Published: October 2022

AbstractObjectiveAlthough increasing evidence suggests a central mechanism of action for sacral neuromodulation, the exact mechanism remains unclear. We set up a scanning paradigm to measure brain activation related to various stages of rectal filling using rectal balloon distention.Materials and MethodsSix healthy volunteers underwent rectal balloon distention during MRI scanning at a 1.5T scanner with a Tx/Rx head coil. MR images were collected at four levels of distention: empty balloon (EB), first sensation volume (FSV), desire to defecate volume (DDV), maximum tolerable volume (MTV). Data were analyzed using BrainVoyager 20.4. Whole brain and ROI-based fixed-effects general linear model analyses were performed on the fMRI time-course data from all participants.ResultsRectal filling until FSV evoked the most blood-oxygen-level-dependent responses in several clusters throughout the cortex, followed by the responses evoked by rectal filling until DDV. Interestingly, rectal filling until MTV evoked negative responses compared to baseline throughout the cortex. No negative side effects were found.DiscussionThis study shows that a standardized paradigm for functional MRI combined with rectal filling is feasible and safe in healthy volunteers and is ready to be used in fecal incontinent patients to assess whether their brain activity differs from healthy controls.
Putting global health high on the agenda of medical schools
Authors: Kutalek Ruth , Lahlal Mina , Kaawa-Mafigiri David , Ryan-Coker Marcella , Böll Simone , Parisi Sandra , Cheah Phaik Yeong , Pritsch Michael 
Published: October 2022

SummaryIn this opinion paper, we reflect on global health and global health education as well as challenges that the coming generation are likely to face. As the field is rapidly changing, it is vital to critically reflect categories of “global south” and “global north” as geographical boundaries, and rather think in terms of inequalities that are present in all countries. Global perspectives on health are useful to analyze structural challenges faced in all health care systems and help understand the diversity of cultures and patients’ concepts of disease. We first discuss burning questions and important challenges in the field and how those challenges are tackled. Rather than going into detail on topical issues, we reflect on approaches and attitudes that we think are important in global health education and present opportunities and challenges for young scholars who are interested in working in this field.
Big data analytics capabilities and MSME innovation and performance: A double mediation model of digital platform and network capabilities
Authors: Bhatti Sabeen Hussain , Ahmed Adeel , Ferraris Alberto , Hirwani Wan Hussain Wan Mohd , Wamba Samuel Fosso 
Published: October 2022

AbstractDrawing on dynamic capabilities and the resource-based view, we propose a conceptual model that encompasses big data analytics capabilities (BDAC), digital platform capabilities and network capabilities, supply chain innovation, and firm performance. We use the structural equation modeling to empirically validate this model on the time-lagged data of 221 micro, small, and medium enterprises (MSMEs) in the manufacturing sectors. The empirical results of our data analysis showed that BDAC significantly improved platform and networking capabilities. BDAC also improved supply chain innovation and thus financial performance. Our data indicated that networking capabilities mediated the relationships of both (a) BDAC-supply chain innovation and (b) BDAC-financial performance. Meanwhile, digital platforms mediated only the BDAC-supply chain innovation relationship. The outcomes of sequential mediation confirmed the role of both digital platform and network capabilities and supply chain innovation in the BDAC-firm performance link. Our results provide theoretical implications to operations management and offer practical insights for managers working in manufacturing MSMEs.
SiaLog: detecting anomalies in software execution logs using the siamese network
Authors: Hashemi Shayan , Mäntylä Mika 
Published: October 2022

AbstractDetecting anomalies in software logs has become a notable concern for software engineers and maintainers as they represent anomalies in software execution paths and states. This paper propose a novel anomaly detection approach based on the Siamese network on top of Recurrent Neural Networks(RNN). Accordingly, we introduce a novel training pair generation algorithm to train the Siamese network which reduces generated training significantly while maintaining the $$F_1$$

F
1

score. Additionally, we propose a hybrid model by combining the Siamese network with a traditional feedforward neural network to make end-to-end training possible, reducing engineering effort in setting up a deep-learning-based log anomaly detector. Furthermore, we provides validations of the approach on the Hadoop Distributed File System (HDFS), Blue Gene/L (BGL), and Hadoop map-reduce task log datasets. To the best of our knowledge, the proposed approach outperforms other methods on the same dataset at the $$F_1$$

F
1

scores of respectively 0.99, 0.99, and 0.94 on HDFS, BGL, and Hadoop datasets, resulting in a new state-of-the-art performance.To further evaluate the proposed method, we examine our method’s robustness to log evolutions by evaluating the model on synthetically evolved log sequences; we got the $$F_1$$

F
1

score of 0.95 on the HDFS dataset at the noise ratio of $$20\%$$

20
%

. Finally, we dive deep into some of the side benefits of the Siamese network. Accordingly, we introduce an unsupervised log evolution monitoring method alongside a visualization technique that facilitates model interpretability.
The Importance of Corporate Reputation for Sustainable Supply Chains: A Systematic Literature Review, Bibliometric Mapping, and Research Agenda
Authors: von Berlepsch David , Lemke Fred , Gorton Matthew 
Published: October 2022

AbstractCorporate Reputation (CR) is essential to value generation and is co-created between a company and its stakeholders, including supply chain actors. Consequently, CR is a critical and valuable resource that should be managed carefully along supply chains. However, the current CR literature is fragmented, and a general definition of CR is elusive. Besides, the academic CR debate largely lacks a supply chain perspective. This is not surprising, as it is very difficult to collect reliable data along supply chains. When supply chains span the globe, data collection is especially challenging, as the chain consists of multiple suppliers and subcontractors, positioned at different tier levels. Recognizing this, the paper examines firstly the current state of CR research through a systematic literature review from a business perspective. The review is combined with a bibliometric mapping approach to show the most influential research clusters, representative of CR research streams and their contributors. This process highlights that the connection between CR and supply chain issues represents a major research gap. Consequently, this paper introduces a research agenda connecting these the two traditionally separated research fields.