bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermodynamic-Dominated Stereoselective Gridization of Molecular Nanolinkage Based on Fluorenes
Authors: Wei Ying , Wang Sha-Sha , Xie Ling-Hai , Li Xiao-Yan , Lin Dong-Qing , Xu Yun-Shan , Li Yang , Zhou Ping , Peng Ai-Zhong , Wang Hong-Jian , Yan Yong-Xia , Shi Wen-Jing 
Published: April 2022

AbstractThe path-selectivity and stereoselectivity of gridization pathways into fluorene-based drawing hand grids (DHGs-F) are precisely modulated through tuning acid conditions and side-chain effects. BF3·OEt2 supports the realization of the gridization path (rac-DHG1-F, yield: 82%, meso-DHG1-F, yield: 11%). On the contrary, CF3SO3H will lead to the enhancements in polymerization pathways (about 85% yield). When the side chain is a methoxyl group, rac-DHG1-F and meso-DHG1-F will be obtained. However, when the side chain is a group without an oxygen atom, only rac-DHGs-F can be obtained (de = 100%). Moreover, through excitonic physical properties, rac-DHGs-F exhibits a more π-electronic delocalization, potentially serving as the intriguing tactic strategy to modulate the optoelectronic properties.
Kinetic Resolution of dl-Hydrobenzoins Catalyzed by Copper(II) Complexes of C 2-Symmetric Thiophene-Derived Ligands
Authors: Reiser Oliver , Vilaivan Tirayut , Mansawat Woraluk , Yukhet Phanomsak , Bhanthumnavin Worawan 
Published: April 2022

AbstractC 2-Symmetrical chiral amino alcohol ligands with a central thiophene moiety were shown to be effective in combination with CuCl2 for the asymmetric acylation of dl-hydrobenzoins. In contrast to previously developed chiral ligands, readily available acetyl chloride and acetic anhydride can be used as reagents, in addition to benzoyl chloride, giving rise to the corresponding monoacylated products in up to 99% ee (S = 532).
Expedient Access to Indolyl-Substituted Tri- and Diarylmethanes and (±)-Colletotryptin E by Silica Sulfuric Acid Catalyzed Transindolylation
Authors: Jaratjaroonphong Jaray , Yimyaem Jirapat , Chantana Chayamon , Boonmee Suthimon 
Published: April 2022

AbstractAn expedient access to a series of nonsymmetrical bis(indolyl)methanes (BIMs) through transindolylation of readily available symmetrical 3,3′-BIMs with various indoles catalyzed by silica-supported sulfuric acid has been established. This approach not only provides a useful strategy for the synthesis of structurally diverse BIMs, but also provides examples of nucleophilic substitution of BIMs with aromatic and nonaromatic π-systems, leading to a library of indolyl-substituted tri- and diarylmethanes. Moreover, this method was successfully applied in the first total synthesis of the 2,3′-BIM alkaloid (±)-colletotryptin E in three steps with an overall yield of 46%. The features of this procedure include a metal-free process, an inexpensive and environmentally friendly catalyst, mild reaction conditions, broad functional-group tolerance, good yields, and gram-scalable preparations.
Analysis of Myelomalacia and Posterior Longitudinal Ligament Ossification as Prognostic Factors in Patients with Cervical Spondylotic Myelopathy Submitted to Laminoplasty
Authors: Antikievicz Desirée Elizabeth Pasqualetto , Rossi Giulio Bartié , Maldaun Marcos Vinicius Calfatt , Gripp Daniel , Marchi Cassiano de , Sousa Luiz Vinícius de Alcantara , Aguiar Paulo Henrique Pires de 
Published: April 2022

Abstract
Background Cervical spondylotic myelopathy is a degenerative disease of the intervertebral disc and the vertebral body of the spine that causes cervical spinal cord injury due to central vertebral canal stenosis. Its prevalence is higher in the elderly. Treatment is usually surgical when the spinal cord is affected either clinically with pyramidal release or radiologically with the altered spinal cord.
Objective The goal of the present study is to analyze the myelomalacia and the ossification of the posterior longitudinal ligament as prognostic factors in the postoperative evolution of patients with cervical canal compression who underwent laminoplasty with the open- or French-door techniques.
Methods We performed a retrospective analysis of 18 surgical cases of spondylotic cervical myelopathy of the same senior neurosurgeon, using the chi-squared test to analyze prognostic factors for patients' postoperative evolution in the Nurick scale, after open-door or French-door laminoplasty.
Findings The comparison between the pre and postoperative showed an improvement of 71.43% in cases that did not have ligament ossification compared with 45.45% of cases that presented posterior longitudinal ligament ossification. Also, there was a better prognosis in patients without myelomalacia, as 71.43% of them improved their condition against only 45.45% of improvement in those with myelomalacia.
Conclusion There is a need for further studies with larger samples to expressively prove that the presence of longitudinal ligament ossification and the previous presence of myelomalacia are factors that can lead to worse prognosis in the postoperative evolution of patients with cervical spondylotic myelopathy submitted to laminoplasty.
Openness in donor conception families
Authors: Macmillan Caitlin M. 
Published: April 2022

AbstractDempsey, Nordqvist and Kelly’s recent publication in BioSocieties highlights the complexity of disclosure in donor conception, which is legally, ethically, and morally challenging. However, contemporary society means that donor-conceived people’s awareness of their conception history can no longer be controlled by their parents. Late, accidental, and non-parent disclosure is becoming more prevalent and can be distressing. Research has consistently found that openness in donor conception families from an early age is optimal, and that disclosure positively impacts rather than threatens family relationships. Despite this, disclosure can be difficult for parents, particularly if they perceive an unsupportive social context. Both donor conception and adoption literature has found more positive outcomes among disclosing families compared to non-disclosing families and interestingly, parents who have chosen to disclose have not reported regret. This response briefly discussed these important considerations and also notes some instances of inaccurate reporting and misleading information in their article.
Economic losses from COVID-19 cases in the Philippines: a dynamic model of health and economic policy trade-offs
Authors: de Lara-Tuprio Elvira P. , Estuar Maria Regina Justina E. , Sescon Joselito T. , Lubangco Cymon Kayle , Castillo Rolly Czar Joseph T. , Teng Timothy Robin Y. , Tamayo Lenard Paulo V. , Macalalag Jay Michael R. , Vedeja Gerome M. 
Published: April 2022

AbstractThe COVID-19 pandemic forced governments globally to impose lockdown measures and mobility restrictions to curb the transmission of the virus. As economies slowly reopen, governments face a trade-off between implementing economic recovery and health policy measures to control the spread of the virus and to ensure it will not overwhelm the health system. We developed a mathematical model that measures the economic losses due to the spread of the disease and due to different lockdown policies. This is done by extending the subnational SEIR model to include two differential equations that capture economic losses due to COVID-19 infection and due to the lockdown measures imposed by the Philippine government. We then proceed to assess the trade-off policy space between health and economic measures faced by the Philippine government. The study simulates the cumulative economic losses for 3 months in 8 scenarios across 5 regions in the country, including the National Capital Region (NCR), to capture the trade-off mechanism. These scenarios present the various combinations of either retaining or easing lockdown policies in these regions. Per region, the trade-off policy space was assessed through minimising the 3-month cumulative economic losses subject to the constraint that the average health-care utilisation rate (HCUR) consistently falls below 70%, which is the threshold set by the government before declaring that the health system capacity is at high risk. The study finds that in NCR, a policy trade-off exists where the minimum cumulative economic losses comprise 10.66% of its Gross Regional Domestic Product. Meanwhile, for regions that are non-adjacent to NCR, a policy that hinges on trade-off analysis does not apply. Nevertheless, for all simulated regions, it is recommended to improve and expand the capacity of the health system to broaden the policy space for the government in easing lockdown measures.
Neutrophil and natural killer cell imbalances prevent muscle stem cell–mediated regeneration following murine volumetric muscle loss
Authors: Larouche Jacqueline A. , Fraczek Paula M. , Kurpiers Sarah J. , Yang Benjamin A. , Davis Carol , Castor-Macias Jesus A. , Sabin Kaitlyn , Anderson Shannon , Harrer Julia , Hall Matthew , Brooks Susan V. , Jang Young C. , Willett Nick , Shea Lonnie D. , Aguilar Carlos A. 
Published: April 2022

SignificanceSkeletal muscle is one of the largest tissues in the body and can regenerate when damaged through a population of resident muscle stem cells. A type of muscle trauma called volumetric muscle loss overwhelms the regenerative capacity of muscle stem cells and engenders fibrotic supplantation. A comparison of muscle injuries resulting in regeneration or fibrosis revealed that intercellular communication between neutrophils and natural killer cells impacts muscle stem cell-mediated repair. Perturbation of neutrophil–natural killer cell interactions resulted in a variation of healing outcomes and suggested that immunomodulatory interventions can be effective to prevent aberrant healing outcomes.
Proteasome complexes experience profound structural and functional rearrangements throughout mammalian spermatogenesis
Authors: Živković Dušan , Sanchez Dafun Angelique , Menneteau Thomas , Schahl Adrien , Lise Sandrine , Kervarrec Christine , Toste Rêgo Ana , da Fonseca Paula C. A. , Chavent Matthieu , Pineau Charles , Burlet-Schiltz Odile , Marcoux Julien , Bousquet Marie-Pierre 
Published: April 2022

Significance
The proteasome is responsible for the homeostasis of intracellular proteins. Here, we describe structural and functional aspects of a poorly characterized proteasome subtype found exclusively in germ cells. The spermatoproteasome was recently shown to be essential for spermatogenesis, a process requiring intense proteolysis. It differs from the constitutive proteasome by only one subunit, α4s, a subunit that replaces its α4 ubiquitous counterpart. In this work, we show how the shift from α4 to α4s regulates proteasome composition, dynamics, interactome, and activity. We reveal a regulation process more complex than previously suggested, which provides the basis for structural and functional studies of the spermatoproteasome.
Nanoparticle targeting of de novo profibrotic macrophages mitigates lung fibrosis
Authors: Singh Abhalaxmi , Chakraborty Sreeparna , Wong Sing Wan , Hefner Nicole A. , Stuart Andrew , Qadir Abdul S. , Mukhopadhyay Amitabha , Bachmaier Kurt , Shin Jae-Won , Rehman Jalees , Malik Asrar B. 
Published: April 2022

Significance
Current therapies for pulmonary fibrosis (PF) focus on slowing disease progression and reducing functional decline in patients by dampening the activation of fibroblasts and other implicated cells. There is a need for strategies that target the essential cells and signaling pathways involved in disease pathogenesis. Monocyte-derived macrophages (Mo-Macs) are known to express profibrotic genes and are involved in the pathogenesis of PF. Our results show that engineered mannosylated albumin nanoparticles specifically targeted disease-inducing Mo-Macs, and further, that nanoparticles efficiently delivered small-interfering RNA against profibrotic cytokine tumor growth factor β1 to prevent bleomycin-induced lung fibrosis.
Discharge characteristics in soil under positive pulse voltage superimposed DC component
Authors: Yang Yong , Pi Xiaoqian , Li Chi , Li Chuan , Zhang Haoqin , Chen Huan , Yu Ziheng , Yang Shuai 
Published: April 2022

Abstract
Considerable research efforts have been devoted to the study of the application of atmospheric discharge in soil remediation. Most of them focused on how to improve the degradation efficiency of specific pollutants. In contrast, the generation and development of discharge in soil is less studied, which restricts the widespread application of soil remediation. Pulse voltage is widely used to trigger discharge in soil, but the requirement for the power supply is relatively high. The current paper proposes a new form of discharge voltage, with positive pulse voltage superimposed on DC bias. The results show that the existence of DC component can effectively lower the required pulse voltage and enlarge the active corona volume, in which area most ionization and excitation happens. The characteristics of corona discharge in soil under DC voltage only, pulse voltage only and superimposed voltage with various voltage components are discussed in detail, according to the volt-ampere characteristics and discharge images from a series of experiments. The mechanism behind the experimental phenomenon are also discussed.
Surface plasmonic waveguide and ultra-wideband bandpass filter using double-layered glide symmetric corrugated lines
Authors: Zhang Xuewei , Liu Shaobin , Liao Kun , Lou Jian 
Published: April 2022

Abstract
In this paper, an ultra-wideband high-efficiency bandpass filter based on a surface plasmonic waveguide (SPW) is proposed. The novel SPW consists of double-sided glide symmetric periodic corrugated metal. The dispersion characteristics of the double-layered glide symmetric SPW are analyzed. By using glide symmetry technology, the dispersion curve for the two lowest-order modes of the proposed SPW is a degeneracy at the Brillouin zone boundary, resulting in a higher propagation constant than the traditional symmetric structure with the same geometry. The dispersion relation of the SPW when glide symmetric conditions are broken is also investigated. Based on the proposed double-layered glide symmetric SPW, we design a bandpass filter working in an ultrawide range of frequencies. To realize the high-efficient transmission of the bandpass filter, the matching structure composed of double-layer grooves with gradient variation is designed for the effective mode conversion of quasi-transverse electromagnetic waves and spoof surface plasmonic polariton. The upper cutoff frequency of the passband can be tuned by adjusting the geometric parameters of the corrugated metal unit, and the lower cutoff frequency can be controlled by modifying the coupling distance with the bottom layer. A prototype of an ultra-wideband bandpass filter has been manufactured and measured, showing a reasonable agreement with simulations. The proposed novel UWB bandpass filter with glide symmetry can be widely used in microwave and millimeter wave related communication systems, and may play an important role in the fabrication of advanced plasma functional devices and circuits.
Lattice dynamics of BaFe2Se3
Authors: Weseloh M J , Balédent V , Zheng W , Verseils M , Roy P , Brubach J B , Colson D , Forget A , Foury-Leylekian P , Lepetit M-B 
Published: April 2022

Abstract
This paper presents a study of the lattice dynamics in BaFe2Se3. We combined first-principle calculations, infrared measurements and a thorough symmetry analysis. Our study confirms that Pnma cannot be the space group of BaFe2Se3, even at room temperature. The phonons assignment requires Pm to be the BaFe2Se3 space group, not only in the magnetic phase, but also in the paramagnetic phase at room temperature. This is due to a strong coupling between a short-range spin-order along the ladders, and the lattice degrees of freedom associated with the Fe–Fe bond length. This coupling induces a change in the bond-length pattern from an alternated trapezoidal one (as in Pnma) to an alternated small/large rectangular one. Out of the two patterns, only the latter is fully compatible with the observed block-type magnetic structure. Finally, we propose a complete symmetry analysis of the BaFe2Se3 phase diagram in the 0–600 K range.
Nonconvex regularized sparse representation in a tight frame for gear fault diagnosis
Authors: Huang Weiguo , Zhang Cheng , Wu Shuyou , Shi Juanjuan , Du Guifu , Zhu Zhongkui 
Published: April 2022

Abstract
A gear’s vibration signal consists of multiple components, so it is therefore difficult to accurately extract the transient components of gear faults. Currently, sparse representation is capable of separating fault components from multicomponent noisy vibration signals. However, sparse representation methods still suffer problems with poor computational efficiency and the underestimation of amplitude. To tackle these challenges, this paper proposes a nonconvex regularized sparse representation in a tight frame. The tunable Q-factor wavelet transform (TQWT) is proposed as a sparse dictionary, which can portray the waveform characteristics of the gear’s vibration signal. TQWT satisfies the tight-frame condition, hence it can efficiently reduce the amount of calculations. The minimax concave function is used as the penalty function since it stands out from various penalty functions with the ability to maintain amplitude. The simulation and experimental analysis show that this method has a shorter operation time and a better ability to maintain the amplitude.
The structure of anionic NbH
n

− (n = 2–15) clusters and their maximum hydrogen capacity
Authors: Liao Y H , Zhou W L , Lyon J T , Peng F , Lu C 
Published: April 2022

Abstract
The geometrical structures of the lowest energy states of anionic niobium-doped hydrogen clusters are determined based on Crystal structure AnaLYsis by the Particle Swarm Optimization (CALYPSO) isomer search method. The geometries and relative stabilities are determined by the B3LYP hybrid density functional theory (DFT) method. The calculated results show that a niobium atom can absorb up to twelve hydrogen atoms in the anionic clusters. In exploring the stability, electronic properties, and photoelectron spectra of NbH
n

− clusters, the NbH12
− cluster is found to possesses a relatively high binding energy, high second-order differential energy, and a large HOMO–LUMO gap. The hydrogen storage density of the NbH12
− cluster is calculated as 11.5 wt%. The present findings enrich the database of transition metal doped hydrogen clusters and the insights are important in the pursuit of efficient hydrogen energy storage materials.
Overview of the HERD space mission
Authors: Kyratzis Dimitrios 
Published: April 2022

Abstract
The High Energy cosmic Radiation Detector (HERD) is a prominent space-borne instrument to be installed on-board the Chinese Space Station (CSS) around 2027, resulting from a collaboration among Chinese and European institutions. Primary scientific goals of HERD include: precise measurements of the cosmic ray (CR) energy spectra and mass composition at energies up to few PeV, electron/positron spectra up to tens of TeV, CR anisotropy, gamma ray astronomy and transient studies, along with indirect searches for Dark Matter candidates. The detector is configured to accept incident particles from both its top and four lateral sides. Owing to its pioneering design, more than one order of magnitude increase in geometric acceptance is foreseen, with respect to previous and ongoing experiments. HERD is conceived around a deep (∼55 X
0, 3 λ

I
) 3D cubic calorimeter (CALO), forming an octagonal prism. Fiber Trackers (FiTs) are instrumented on all active sides, with a Plastic Scintillator Detector (PSD) covering the calorimeter and tracker. Ultimately, a Silicon Charge Detector (SCD) envelops the above-stated sub-detectors, while a Transition Radiation Detector (TRD) is instrumented on one of its lateral faces, for energy calibration in the TeV scale. This work illustrates HERD’s latest advancements and scientific objectives along with an overview of upcoming activities.
Incoherent control of Goos–Hänchen shifts in a tunneling quantum dot molecule
Authors: Darkhosh Ahad , Sahandi Rima 
Published: April 2022

Abstract
In this letter, we propose a novel model for adjusting the Goos–Hänchen shifts (GH) from a fixed cavity. A three-level double quantum dot (QD) molecule is doped in the cavity, which interacts with a probe laser field and an incoherent pumping rate. We initially investigate the refraction index of double QDs utilizing the quantum mechanical density matrix approach in order to achieve negative and positive refractive indexes. The GH shifts of reflected and transmitted light beams in positive and negative refraction indices of the intracavity medium were then studied. The improved negative or positive GH shifts in reflected and transmitted light beams may be accomplished by changing the incoherent pumping rate and tunneling effect. Our findings reveal that the magnitude of the GH shifts is greatly influenced by the absorption of incoming probing light in double QDs. The enormous GH shifts for the perfect tuning cavity have been seen at a given incidence angle.
Characterizing the short-latency evoked response to intracortical microstimulation across a multi-electrode array
Authors: Sombeck Joseph T , Heye Juliet , Kumaravelu Karthik , Goetz Stefan M , Peterchev Angel V , Grill Warren M , Bensmaia Sliman , Miller Lee E 
Published: April 2022

Abstract

Objective. Persons with tetraplegia can use brain-machine interfaces to make visually guided reaches with robotic arms. Without somatosensory feedback, these movements will likely be slow and imprecise, like those of persons who retain movement but have lost proprioception. Intracortical microstimulation (ICMS) has promise for providing artificial somatosensory feedback. ICMS that mimics naturally occurring neural activity, may allow afferent interfaces that are more informative and easier to learn than stimulation evoking unnaturalistic activity. To develop such biomimetic stimulation patterns, it is important to characterize the responses of neurons to ICMS. Approach. Using a Utah multi-electrode array, we recorded activity evoked by both single pulses and trains of ICMS at a wide range of amplitudes and frequencies in two rhesus macaques. As the electrical artifact caused by ICMS typically prevents recording for many milliseconds, we deployed a custom rapid-recovery amplifier with nonlinear gain to limit signal saturation on the stimulated electrode. Across all electrodes after stimulation, we removed the remaining slow return to baseline with acausal high-pass filtering of time-reversed recordings. Main results. After single pulses of stimulation, we recorded what was likely transsynaptically-evoked activity even on the stimulated electrode as early as ∼0.7 ms. This was immediately followed by suppressed neural activity lasting 10–150 ms. After trains, this long-lasting inhibition was replaced by increased firing rates for ∼100 ms. During long trains, the evoked response on the stimulated electrode decayed rapidly while the response was maintained on non-stimulated channels. Significance. The detailed description of the spatial and temporal response to ICMS can be used to better interpret results from experiments that probe circuit connectivity or function of cortical areas. These results can also contribute to the design of stimulation patterns to improve afferent interfaces for artificial sensory feedback.