bluuebunny/crossref_metadata_2025_split huggingface dataset:
Propolis protects the lungs from radiation-induced systemic oxidative damage
Authors: TAYLAN Mahsuk , DOGRU Sibel , TAYSI Seyithan 
Published: October 2022

Abstract
Background: Propolis is well known as an antioxidant natural product. This study aimed to detect the radioprotective effect of propolis against oxidative lung injury caused by cranial irradiation.
Methods: Thirty-two rats were randomly divided into four equal groups. Group A, sham control group (n = 8); group B,propolis control group (n = 8);group C,irradiation alone group (n = 8);and group D,irradiation plus propolis group (n = 8). The latter two groups were exposed to a single dose (5 Gy) of cranial irradiation. The saline dosage was 1 mL/kg/day, and the propolis dosage was 80 mg/kg/day. The total oxidant status(TOS), total antioxidant status (TAS), oxidative stress index (OSI), arylesterase, lipid hydroperoxide (LOOH), ceruloplasmin, total thiol (SH), and paraoxonase (PON) levels of lung tissues were measured.
Result: TOS, OSI, and lipid hydroperoxide levels were significantly higher in group C than in all other groups. TOS, OSI, and lipid hydroperoxide were significantly lower, and TAS and total thiol levels were higher in group D than in group C.
Conclusion: The use of propolis has a significant protective effect against the adverse effects of oxidative stress-related lung injury caused by ionizing radiation.
Cross-linguistic Authorship Attribution and Author Profiling. Is Machine Translation the Solution?
Authors: Mikros George , Boumparis Dimitris 
Published: October 2022

Abstract
This paper aims to explore whether cross-linguistic authorship attribution and author's gender identification are feasible using Machine Translation (MT) as a method to bridge the language gap. We designed a series of computational stylistics experiments to explore whether the stylometric signal survives through the MT process. We compiled an extensive blog corpus in Greek containing 100 authors, balanced in gender with 50 texts from each author. Then, we used Google's Neural Machine Translation to automatically translate each text into English. We ran several classification experiments using the Random Forest algorithm in authorship attribution and gender profiling tasks employing different feature groups in both the source language (Greek) and the machine-translated (English) corpora. Moreover, we trained models in the source language and used the texts in the target language as the unseen test set, to simulate a cross-linguistic prediction. The results showed that cross-linguistic gender identification could be achieved reliably using n-gram features. Authorship attribution, however, was not feasible in our cross-linguistic experimental setting, although features of lexical diversity exhibited promising results. Finally, when performed using training and testing set from the same language, both authorship attribution and gender identification exhibit similar accuracy across the full range of the feature groups used.
Effect of Influencing Parameters on Developing Aluminium Metal Foam by using Powder metallurgy technique with foaming agent as a Wax Powder
Authors: Madgule Mahadev , G Sreenivasa C , Borgaonkar Avinash V. 
Published: October 2022

Abstract
Aluminum metal foam has become an advanced popular material because it has excellent mechanical and electrical properties and is lightweight. The present work developed the Aluminium metal foam specimen using wax powder as a blowing agent through the powder metallurgy method. The effect of process parameters such as powder size, stirring speed, sintering temperature, and foaming agent content on the mechanical behavior of the developed specimens has been studied experimentally. In the design of experiments, the Taguchi orthogonal L9 array has been implemented. The percentage of Porosity was estimated using the Archimedes principle, and mechanical behaviors such as flexural, tensile, and compressive strength were determined. The ANOVA analysis of variance it's been carried out to check the significant parameters affecting the mechanical behavior of developed specimens. It was observed that the powder size is the highly significant parameter, followed by stirring speed, the content of the foaming agent, and sintering temperature. The Maximum Porosity 71.30%, Compresssion strength 12.01MPa, Tensile strength 6.16 MPa, Flexural strength 5.18 MPa. The microstructure study reveals that there is no any adequet compostion in the specimen. The novelty in this research work is using a novel foaming agent as a Wax powder to develop aluminium metal foam and attained good properties.
Ionogel-Electrode for the Study of Protein Tunnel Junctions under Physiologically Relevant Conditions
Authors: Bai Xiyue , Li Pengfei , Peng Wuxian , Chen Ningyue , Lin Jin-Liang , Li Yuan 
Published: October 2022

Abstract
The study of tunneling through proteins is essential for the understanding of complicated electrochemical processes in biological activities. Both electron transport and transfer phenomena are found in protein junctions, but the reason remains unknown. In this work, we polymerized an ionic liquid into a conductive and flexible electrode, and used it as a top-contact to form highly reproducible molecular junctions of protein molecules on a silver bottom-electrode. The junctions of proteins, choice of which including human serum albumin, cytochrome C or hemoglobin, show temperature independent electron transport characteristics, when junctions are in solid states; but all junctions can be switched to temperature dependent electron transfer, when junctions are hydrated in water. We experimentally for the first time show that it requires about 100 − 120 meV for electrons passing through one heme group inside a hydrated protein molecule.
Pregnancy-related anxiety and its relationship with perceived social support, family function and resilience among Chinese pregnant women—A structural equation model analysis
Authors: Huang Jingui , Xu Lingli , Xu Zhen , Luo Yexin , Liao Bizhen , Li Yan , Shi Yumei 
Published: October 2022

Abstract
Background
Accumulating evidence suggests that pregnancy-related anxiety (PRA) has adverse impacts on maternity health and infant development. A substantial body of literature has documented the important influence of family function, perceived social support and resilience on PRA. However, research identifying the mediating mechanisms underlying this relationship in China are still lacking. Therefore, the current study aimed to investigate the prevalence of PRA under the three-child policy in China, and also explore whether resilience mediated the effect of family function and perceived social support on PRA.
Methods
A total of 579 pregnant women were recruited in this cross-section study from a teaching hospital in Chongqing, China. Participants were required to complete the following questionnaires: the demographic form, the Chinese Pregnancy-related Anxiety scale, the 10-item Connor-Davidson Resilience Scale, the APGAR Family Care Index Scale, and Multidimensional Scale of Perceived Social Support. Pearson correlation analysis was utilized to examine the rudimentary relationship among the study variables. Bootstrapping analyses in the structural equation modeling were applied to identify the significance of indirect effects.
Results
There were 41.4% of pregnant Chinese women indicating PRA. Correlational analyses indicated that perceived social support, family function and resilience were negatively associated with PRA (r = -0.47, P < 0.01; r = -0.43, P < 0.01; r = -0.37, P < 0.01, respectively). The results of bootstrapping analyses demonstrated significant indirect effects of perceived social support (β = -0.098, 95% CI [-0.184, -0.021]) and family function (β = -0.049, 95% CI [-0.103, -0.011]) on PRA via resilience.
Conclusions
Chinese pregnant women are suffering from high levels of PRA. Better family function and perceived social support might reduce the occurrence of PRA, as well as by the mediating effects of resilience.
The Effect of Vestibular Stimulations on Virtual Reality Based Bodily Self Consciousness
Authors: Yaman Handan , Hajebrahimi Farzin , Hanoğlu Lütfü 
Published: October 2022

Abstract
Background
Consciousness is classically described as alertness and awareness. Damasio claims that this change is not enough for consciousness to emerge, that a basic element is missing, which is the "self". The purpose of this study was to investigate the role of electrical vestibular stimulation (VS) in the formation of bodily self-consciousness in healthy individuals by utilizing brain hemodynamic activations with the functional Near Infrared Spectroscopy (fNIRS) system.
Methods
The study protocol included three sessions: a session without VS, a VS session with application on the right temporo-parietal junction (rTPJ) and a VS session with application on the mastoid level with transcranial direct current stimulation (tDCS).
Results
In VS provided at the rTPJ level, unlike the other sessions, increased hemodynamic activation was observed at primary somatosensory cortex-supramarginal gyrus in the left lobe and in the supramarginal gyrus in the right lobe. In VS provided on the mastoid level, increased hemodynamic activation was observed in secondary somatosensory cortex-ventral posterior cingulate cortex connection on left lobe, which we did not observe in other sessions.
Conclusion
After artificial VS, the perception of bodily ownership in individuals requires coding of personal space information as well as vestibular information processing and extrapersonal space integration information.
Does Body Mass Index affect the outcomes of patients undergoing unicompartmental knee arthroplasty? A retrospective cohort study
Authors: Xuequan Zhao , Li Dezhi , Bin Zhao , Shuzhang Yao , Qinglei Liu 
Published: October 2022

Abstract
Background: Unicompartmental knee arthroplasty（UKA） has become one of the main methods for the treatment of unicompartmental knee osteoarthritis. There is still lack of medium term data on the outcomes of UKA and survival rate of prosthesis in different body mass index (BMI) groups.
Objective: we focus on the effectof BMI on the medium clinical outcomes of UKA.
Methods: The retrospective study included patients who received UKA at our hospital, between January 1, 2014 to December 31, 2017.All patients All patients underwent surgery of unicompartmental knee arthroplasty. They were divided into three groups according to BMI. normal body mass group [group A, BMI 14.50～24.99 kg/m2, 14 cases (16 knees)], overweight group [group B, BMI 25.00-27.99 kg/m2, 15 cases (17 knees)], obesity group[group C, BMI 28.00-39.99 kg/m2, 16 cases (18 knees)]. There was no significant difference in gender, age, sides, diseaseduration, and preoperative American Special Surgery Hospital (HSS) score, pain visual analogue scale (VAS) score, and knee range of motion (ROM) among 3 groups (P>0.05). The operation time, intraoperative dominant blood loss, and the postoperative decreased amount of hemoglobin at 2 week were recorded and compared among 3 groups. The the Knee Society Score (KSS), the University of California at Los Angeles (UCLA) activity scale，Knee society score ，VAS score, and ROM were evaluated in three groups.
Results: Forty-five of 58 eligible patients were included. All the 45 patients were followed up 36-70 months, with an average of 57.55 months. The function of knee joint in all patients was improved and the pain was obviously relieved. Significant differences were found in the knee score, function score and the knee society score between three groups at 70-month follow-up (p<0.05).
Conclusions: For normal and overweight patients with anterior medial compartmental osteoarthritis of the knee joint, the use of minimally invasive UKA can achieve satisfactory short- and medium-term effectiveness. However, this procedure should be chosen carefully with overweight patients.
Natural compound So-2 suppresses triple-negative breast cancer through inducing ferroptosis via downregulating transcription factor E2F7.
Authors: Liu Na , Zhang Jing , Duan Wenqi , Luo Tingting , Wu Cong , Han Lina , Yang Fengying , Yue Hongwei , Ge Di 
Published: October 2022

Abstract
Background
Siegesbeckia orientalis L. have been used as a traditional Chinese medicine “Xi-Xian-Cao” for centuries with multiple medicinal benefits including cancerous treatment. Breast cancer is one of the leading causes of death in women worldwide. And the Triple-negative breast cancer (TNBC), accounting for about 15 ~ 18% of all breast cancers, is notorious for its poor prognosis, high rate of relapse and short overall survival. Because of lacking effective therapeutic targets or drugs, treatment of TNBC in clinical encounters great obstacle. Recently, we have reported the isolation of twenty-seven germacranolides including So-2 from the aerial parts of S. orientalis with potent cytotoxicity against breast cancer cells. However, the specific mechanism needs to be elucidated. The aim of this study is to verified the anti-tumor function of the natural compound So-2 and uncover the underlying mechanism.
Methods
We investigated the anti-tumor role of So-2 both in vitro and in vivo. An orthotopic transplantation tumor model was established to assess the in vivo antitumor effects of So-2. Two TNBC cell lines MDA-MB-231 and BT-549 cells were employed to study the cytotoxicity effect and specific mechanism of So-2 in vitro. We studied the influence of So-2 on TNBC cell proliferation, migration and ferroptosis in detail.
Results
So-2 was shown to cause cell cycle arrest and suppress TNBC cell proliferation and migration. Also, So-2 was identified to be a bona fide ferroptosis inducer in TNBC cells. We also characterized the oncogenic role of the transcription factor E2F7 in TNBC. And E2F7 was downregulated by So-2 while inducing ferroptosis. E2F7 was demonstrated to be involved in the ferroptosis-inducing and tumor suppression effect of So-2.
Conclusion
So-2 exhibits inhibitory effect on TNBC growth and migration both in vitro and vivo by inducing TNBC ferroptosis via downregulating the expression of E2F7. These findings provide valuable insight into the pathogenesis of TNBC. The natural compound So-2, isolated from Chinese traditional medicine, might be a prospective drug candidate in TNBC therapy.
Advanced quantum image representation and compression using a DCTEFRQI approach
Authors: HAQUE MD ERSHADUL , Paul Manoranjan , Ulhoq Anwar , Debnath Tanmoy 
Published: October 2022

Abstract
In recent years, quantum image processing got a lot of attention in the field of image processing due to the opportunity to place huge image data in quantum Hilbert space. Hilbert space or Euclidean space has infinite dimensions to locate and process the image data faster. Moreover, several types of research show that the computational time of the quantum process is faster than classical computers. Encoding and compressing the image in the quantum domain is still a challenging issue. From the literature survey, we have proposed a DCT-EFRQI (Direct Cosine Transform Efficient Flexible Representation of Quantum Image) algorithm to represent and compress gray image efficiently which save computational time and minimize the complexity of preparation. This work aims to represent and compress various gray image sizes in quantum computers using the DCT (Discrete Cosine Transform) and EFRQI (Efficient Flexible Representation of Quantum Image) approaches together. The Quirk simulation tool is used to design the corresponding quantum image circuit. Due to the limitation of qubits, a total of 16 numbers of qubits is used to represent the coefficient and its position of the grayscale image. Among those, 8 number of qubits are used to map the coefficient values and the rest are used to generate the corresponding coefficient XY-coordinate position. Theoretical analysis and experimental results show that the proposed DCT-EFRQI scheme provides better representation and compression compared to DCT-GQIR, DWT-GQIR, and DWT-EFRQI in terms of PSNR(Peak Signal to Noise Ratio), and bit rate.
A comparative study of the antioxidant, antibacterial and cytotoxic activities of different varieties of imported ripe cavendish banana
Authors: Al-Abri Faisal Said Hamed , Hossain Mohammad Amzad 
Published: October 2022

Abstract
Banana is one of the most delicious and energetic crops among the agricultural crops. Traditionally, Omanis used bananas to treat gastrointestinal disorders, constipation and diarrhea. The present study aims to determine different pharmacological and toxicological activities of extracts of two varieties of imported ripe banana which was collected in the local fruits and vegetable market. Extracts from ipe bananas imported from India and the Philippines were prepared separately l by soaking the bananas in methanol for seventy-two hours. The prepared banana extracts were fractionated with various solvents with increasing pattern of polarity to give corresponding banana crude extract, respectively. All prepared crude extracts were used to determine their antioxidant, antibacterial and cytotoxic activities by using 2,2-diphenyl-1-picrylhydrazyl (DPPH), agar gel diffusion and brine shrimp lethality methods. In case of the Indian ripe banana, the highest antioxidant activity was obtained from the ethyl acetate extract and the water crude extract showed the lowest activity. However, in the ripe banana from the Philippines, the highest activity was obtained from the chloroform crude extract and the lowest activity was obtained from the water extract. Both extracts with different polarity displayed moderate antibacterial activity at different working concentrations. The zone of inhibition range was 0-19 mm against one Gram-positive bacterial strain such as Staphylococcus aureus (S. aureus) and three Gram-negative bacterial strains such as Escherichia coli (E. coli), Haemophilus influenza (H. influenza) and Enterococcus faecalis. Both banana extracts with different polarity showed significant cytotoxic activity at all working concentrations. Both banana crude extracts killed all shrimp nauplii at the highest concentration of 500 μg/ml. In Indian ripe banana, the highest cytotoxic activity was found in water crude extract with an LC50 value of 27.35μg/ml and the lowest was in ethyl acetate and methanol extract with an LC50 value of 57.54 μg/ml. Almost similar results were obtained from the bananas from the Philippines. In conclusion, the polar crude extracts prepared from both varieties of ripe bananas have significant pharmacological and toxicological activities. Therefore, the polar banana extracts might be agents to be used as antibiotics.
Generation of axial multi foci pattern
Authors: Thiruarul D. , Charles J. William , Lavanya M. , Rajesh K. B. , Jaroszewicz Z. 
Published: October 2022

Abstract
Axially splitted multi foci(AMF) are numerically generated by tight focusing of higher order cylindrical vector beam(HCVB) through an annular Walsh filter .Here we report that by properly manipulating the parameters of HCVB such as initial phase(φ0),topological charge (m), polarization rotation angle or azimuthal index (a) and suitably phase modulated with a Walsh function filter of fixed orders (n) and annular obstruction (ε),onecan generate axially polarized multiple spots,transversely polarized multiple holes,transversely polarized multi spots,axially and transversely polarized multi holes with extended central annular region.These distributions may be useful for multiple optical trapping and axial superresolution microscopy.
Past and future of land use change in the Middle reaches of the Yellow River Basin in China
Authors: Liu Xiaofeng , Hong Zenglin , Zhou Luhong , Liu Jiaqi , Guo Xiaodan , Li Shifeng 
Published: October 2022

Abstract
When looking at maps of land use land cover (LULC) change, often derived from satellite imagery, China's increasing urban construction and decreasing cultivated land area can be identified. Using the middle reaches of the Yellow River Basin in China as the case study, the present work focuses on (i) identifying historical LULC change in the period 1995–2020; (ii) estimating LULC in the next ten years, combining Geographical Information Systems (GIS) with Markov model. Landsat 5/8 images were combined with field evidence to map LULC in three reference years (1995, 2005, 2015and2020), while the Markov model was applied to forecast LULC in 2025, and 2030.The LULC of the middle reaches of the Yellow River Basin was classified into six classes: forest, grassland, wetland, cultivated land, construction land and unused land. The results show that over the past 25 years, cultivated land and forest land have decreased by 8,600 km2 and 6,400 km2, respectively, while construction land has increased by 7,500 km2, mainly due to increased urbanization and industrialization. In fact, during the simulated 2020–2030 period, cultivated land and forest land will continue to decrease, while construction land and grassland will increase. It is worth noting that the reduction of forest land will lead to increased soil erosion, while the reduction of cultivated land will lead to food security problems. The study points out that there is an urgent need for response measures in the region to ensure the sustainability of people and nature.
Population norms for the Romanian version of EQ-5D-3L and EQ-5D- 5L
Authors: Olariu Elena , Caplescu Raluca , Vale Luke , Niculescu-Aron Ileana Gabriela , Oluboyede Yemi , Paveliu Marian Sorin 
Published: October 2022

Abstract

Background The majority of patient reported outcome measures (PROMs) don’t have population norms in Romania. This is the case with the EQ-5D as well. Therefore, we aimed to estimate population norms for the Romanian versions of the EQ-5D-5L, EQ-5D-3L, their indexes, and the EQ-VAS. Methods A cross-sectional survey was conducted in all regions of Romania from November 2018 to November 2019. A three-stage probability sampling procedure stratified by region and settlement size was used to select a representative sample. Interviews were computer-assisted and conducted in respondents’ homes by trained interviewers. Health status was assessed with the EQ-5D-5L, the EQ-5D-3L and the EQ-VAS. Descriptive statistics were used to estimate population norms by age groups and sex for the EQ-5D-5L, the EQ-5D-3L, their indexes and the EQ-VAS. Population norms were weighted using survey weights. Indexes for the EQ-5D questionnaires were estimated using the recently developed Romanian value sets. Results Data from 1,649 interviews was analysed in the present study. Survey weights were used so that sex and place of residence ratios for the weighted sample matched the Romanian general population distribution. Participants’ mean age was 47.5 years (SD = 17.9) and 50.3% of them reported being in good health. The dimension for which people reported the fewest problems for both questionnaires was the self-care dimension. Men aged 35 plus reported fewer problems with pain/discomfort than women for both the EQ-5D-5L and EQ-5D-3L. Health decreased with age as shown by the decrease from age group 18–24 to age group 75 plus in the indexes of both questionnaires: from 0.978 (SD = 0.048) to 0.774 (SD = 0.168) for EQ-5D-5L and from 0.981 (SD = 0.053) to 0.790 (0.164) for EQ-5D-3L. There was 29.6 points drop in the EQ-VAS score between the youngest and oldest group. Conclusions Population norms for the Romanian versions of the EQ-5D-5L, EQ-5D-3L, their indexes, and the EQ-VAS are now available. These can now be used as reference values by healthcare professionals, researchers and decision-makers leading to a further development of health-related quality of life research in Romania.