bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetic Resonance Imaging Negative Spine Trauma Followed by a Delayed Intravertebral Vacuum Cleft–Kümmell's Disease: A Case Report and Literature Review
Authors: Gou Pengguo , Jing Wanli , Zhou Jiaming , Wang Rui , Wang Zun , Chang Feng , Xue Yuan 
Published: October 2022

BackgroundKümmell's disease (KD) is a rare clinical entity characterized by delayed post‐traumatic vertebral body collapse, in which an intravertebral vacuum cleft (IVC) is formed. The patient sustained a minor spinal trauma, and their spine X‐ray examinations were negative. However, after an asymptomatic period of months, they developed recurrent back pain because of the progressive vertebral collapse of the affected spine. However, no imaging examination could confirm the magnetic resonance imaging (MRI)‐negative initial spinal trauma followed by delayed vertebral collapse with IVC.Case PresentationWe report a case of KD occurring in a 66‐year‐old postmenopausal patient whose lumbar MRI on sagittal planes were immediately performed following the initial trauma (a ground‐level fall) and revealed that the vertebral integrity or connectivity was not interrupted and the marrow signal was even. After an asymptomatic period of 8 months, the back pain reappeared and progressively exacerbated. The wedge‐shaped change in the T11 vertebra with an IVC was confirmed by lumbar computed tomography and MRI. Finally, KD was diagnosed following extensive routine hematological and biochemical workups. Percutaneous kyphoplasty was performed to relieve her back pain by restoring her vertebral stability.ConclusionsWe confirmed that the OVF was not the first step in the KD sequence, and the IVC ‐ KD ‐ could from an initial MRI‐negative spine trauma.
The early bud gets the cold: Diverging spring phenology drives exposure to late frost in aPicea mariana[(Mill.)BSP] common garden
Authors: Mura Claudio , Buttò Valentina , Silvestro Roberto , Deslauriers Annie , Charrier Guillaume , Raymond Patricia , Rossi Sergio 
Published: October 2022

AbstractUnder climate change, the increasing occurrence of late frost combined with advancing spring phenology can increase the risk of frost damage in trees. In this study, we tested the link between intra‐specific variability in bud phenology and frost exposure and damages. We analysed the effects of the 2021 late frost event in a black spruce (Picea mariana(Mill.) BSP) common garden in Québec, Canada. We hypothesised that the timing of budbreak drives the exposure of vulnerable tissues and explains differences in frost damage. Budbreak was monitored from 2015 to 2021 in 371 trees from five provenances originating between 48° and 53° N and planted in a common garden at 48° N. Frost damages were assessed on the same trees through the proportion of damaged buds per tree and related to the phenological phases by ordinal regressions. After an unusually warm spring, minimum temperatures fell to −1.9°C on May 28 and 29, 2021. At this moment, trees from the northern provenances were more advanced in their phenology and showed more frost damage. Provenances with earlier budbreak had a higher probability of damage occurrence according to ordinal regression. Our study highlights the importance of intra‐specific variability of phenological traits on the risk of frost exposure. We provide evidence that the timings of bud phenology affect sensitivity to frost, leading to damages at temperatures of −1.9°C. Under the same conditions, the earlier growth reactivation observed in the northern provenances increases the risks of late frost damage on the developing buds.
Effects of the learning tasks and the leadership profile of the coach on the perception of decision‐making in young
Authors: de Albuquerque Luís Rogério , Scheeren Eduardo , Vagetti Gislaine , Oliveira Valdomiro 
Published: October 2022

AbstractThe objective of the research was to investigate the effects of the learning tasks and leadership profile of the coach on the subjective perception of decision‐making. In total, 910 Brazilian adolescents (14.00 ± 1.8 years) and 57 Brazilian coaches (45.57 ± 7.25 years) were included in the study, participants of a sports program in 37 public schools in the city of Curitiba in the state of Paraná. Ordinal logistic regression was used to verify the independent associations between the variables and the tertiles of the scores for each decision‐making characteristic. The small‐sized game learning tasks were positively associated with commitment to decision‐making learning (CR = 1.21, 95% CI = 1.01–1.49). Positive associations were also found between the coaches' leadership profile and decision‐making competence.
Systematics and evolution of predatory flower flies (Diptera: Syrphidae) based on exon‐capture sequencing
Authors: Mengual Ximo , Mayer Christoph , Burt Trevor O. , Moran Kevin M. , Dietz Lars , Nottebrock Gaby , Pauli Thomas , Young Andrew D. , Brasseur Marie V. , Kukowka Sandra , Kelso Scott , Etzbauer Claudia , Bot Sander , Hauser Martin , Jordaens Kurt , Miranda Gil F. G. , Ståhls Gunilla , van Steenis Wouter , Peters Ralph S. , Skevington Jeffrey H. 
Published: October 2022

AbstractFlower flies (Diptera: Syrphidae) are one of the most species‐rich dipteran families and provide important ecosystem services such as pollination, biological control of pests, recycling of organic matter and redistributions of essential nutrients. Flower fly adults generally feed on pollen and nectar, but their larval feeding habits are strikingly diverse. In the present study, high‐throughput sequencing was used to capture and enrich phylogenetically and evolutionary informative exonic regions. With the help of the baitfisher software, we developed a new bait kit (SYRPHIDAE1.0) to target 1945 CDS regions belonging to 1312 orthologous genes. This new bait kit was successfully used to exon capture the targeted loci in 121 flower fly species across the different subfamilies of Syrphidae. We analysed different amino acid and nucleotide data sets (1302 loci and 154 loci) with maximum likelihood and multispecies coalescent models. Our analyses yielded highly supported similar topologies, although the degree of the SRH (global stationarity, reversibility and homogeneity) conditions varied greatly between amino acid and nucleotide data sets. The sisterhood of subfamilies Pipizinae and Syrphinae is supported in all our analyses, confirming a common origin of taxa feeding on soft‐bodied arthropods. Based on our results, we define Syrphini stat.rev. to include the genera Toxomerus and Paragus. Our divergence estimate analyses with beast inferred the origin of the Syrphidae in the Lower Cretaceous (125.5–98.5 Ma) and the diversification of predatory flower flies around the K–Pg boundary (70.61–54.4 Ma), coinciding with the rise and diversification of their prey.
Relocating to a new facility: The challenge of a cord blood banking transferral in Brazil
Authors: Ogliari Karolyn Sassi , Loth Fabrizio Blank , Halon Maria Laura , Immig Monica Luiza , da Silva Camila Gomes , Ogliari Alícia Sassi , De Lima Brum Dário Eduardo , Beckenkamp Liziane Raquel 
Published: October 2022

AbstractBackgroundOur cord blood banking facility planned and executed a transferral of its entire operation to a new site in the South of Brazil. Transporting LN2 freezers is a complex process in which extensive planning is essential to minimize the risks of damaging products or storage units.MethodsTo fulfill this objective, we constructed a detailed relocation plan consisting of four phases and risk mitigation measures, collaborated with the representatives of all departments, regulating agencies, and professionals from the transport company, and assembled a validation plan for cryogenic freezers and the viability of cord blood units.ResultsThe new facility was prepared in accordance with the project plan, local legislation, quality system program requirements, and accreditation agency guidance. A 12‐h operation of moving the cryogenic freezers was conducted successfully, with no loss or damage of client samples or equipment.ConclusionThrough the development and execution of a transferral plan, the engagement of appropriate partners, and compliance with security measures from health and government agencies, a successful transferral of a cord blood banking facility operation in its entirety can be successfully accomplished.
Echocardiographic, thoracic ultrasonographic, and CTA diagnosis of pericardial neoplasia in a dog
Authors: Morey Alice G N , Wiggen Kelly E , De New Kara , Karnia James J 
Published: October 2022

AbstractA 12‐year‐old male neutered Yorkshire Terrier presented for coughing and respiratory distress. Transthoracic echocardiography initially misdiagnosed the patient with pericardial effusion; repeat echocardiography increased suspicion for neoplasia. A definitive diagnosis was not apparent. Findings on thoracic computed tomography and thoracic ultrasound were consistent with a diffusely thickened, heterogenous, hypoechoic soft tissue structure surrounding the heart. Fine needle aspirates were obtained using ultrasound guidance and routine cytology of the intrapericardial mass was consistent with neoplasia, with pericardial mesothelioma most likely. These novel findings highlight the importance of thoracic ultrasound and potential limitations of echocardiography in diagnosis of pericardial neoplasia.
Managing life-threatening 5-fluorouracil cardiotoxicity
Authors: Boldig Kimberly , Ganguly Anupriya , Kadakia Meet , Rohatgi Abhinav 
Published: October 2022

5-Fluorouracil (5-FU), a known cardiotoxin, is the backbone for the treatment of colorectal cancer. It is associated with arrhythmias, myocardial infarction and sudden cardiac death. Most commonly, it is associated with coronary vasospasm secondary to direct toxic effects on vascular endothelium.A woman with metastatic colon cancer, originally treated with a 5-FU infusion as part of the FOLFIRI (Folinic acid, 5-Fluorouracil, Irinotecan) regimen, was unable to tolerate the chemotherapy due to chest pain. She was transitioned from infusional 5-FU to inferior 1-hour bolus 5-FU, in an attempt to minimise cardiotoxicity, but had disease progression. A multidisciplinary decision was made to again trial 5-FU infusion and pretreat with diltiazem. She tolerated chemotherapy without adverse events. A multidisciplinary discussion is recommended for co-management of reversible 5-FU-associated cardiotoxicity. After coronary artery disease (CAD) risk stratification and treatment, empiric treatment with calcium channel blockers and/or nitrates may allow patients with suspected coronary vasospasm, from 5-FU, to continue this vital chemotherapy.
Adolescent birth rates and the urban social environment in 363 Latin American cities
Authors: Braverman-Bronstein Ariela , Vidaña-Pérez Dèsirée , Ortigoza Ana F , Baldovino-Chiquillo Laura , Diez-Canseco Francisco , Maslowsky Julie , Sánchez Brisa N. , Barrientos-Gutiérrez Tonatiuh , Diez Roux Ana V. 
Published: October 2022

IntroductionLatin America has the second-highest adolescent birth rate (ABR) worldwide. Variation between urban and rural areas and evidence linking country development to ABR points towards upstream factors in the causal pathway. We investigated variation in ABR within and between cities, and whether different features of urban social environments are associated with ABR.MethodsWe included 363 cities in 9 Latin American countries. We collected data on social environment at country, city and subcity levels and birth rates among adolescents (ages 15–19). We investigated variation in ABR within and between countries and cities along with associations between social environment and ABR by fitting three-level negative binomial models (subcities nested within cities nested within countries).ResultsThe median subcity ABR was 58.5 per 1000 women 15–19 (IQR 43.0–75.3). We found significant variability in subcity ABR between countries and cities (37% of variance between countries and 47% between cities within countries). Higher homicide rates and greater population growth in cities were associated with higher ABR (rate ratio (RR) 1.09; 95% CI 1.06 to 1.12 and RR 1.02; 95% CI 1.00 to 1.04, per SD, respectively), while better living conditions and educational attainment in subcities were associated with lower ABR after accounting for other social environment characteristics (RR 0.95; 95% CI 0.92 to 0.98 and 0.78; 95% CI 0.76 to 0.79, per SD, respectively).ConclusionsThe large heterogeneity of ABR found within countries and cities highlights the key role urban areas have in developing local policies. Holistic interventions targeting education inequalities and living conditions are likely important to reducing ABR in cities.
Cross-sectional study for COVID-19-related mortality predictors in a Brazilian state-wide landscape: the role of demographic factors, symptoms and comorbidities
Authors: Gustani-Buss Emanuele Gustani , Buss Carlos E , Cavalli Luciane R , Panis Carolina , Tuon Felipe F , Telles Joao P , Follador Franciele A C , Wendt Guilherme W , Lucio Léia C , Ferreto Lirane E D , de Oliveira Isabela M , Carraro Emerson , David Lualis E , Simão Andréa N C , Boldt Angelica B W , Luiza Petzl-Erler Maria , Silva Wilson A , Figueiredo David L A 
Published: October 2022

ObjectiveThe Brazilian state of Paraná has suffered from COVID-19 effects, understanding predictors of increased mortality in health system interventions prevent hospitalisation of patients. We selected the best models to evaluate the association of death with demographic characteristics, symptoms and comorbidities based on three levels of clinical severity for COVID-19: non-hospitalised, hospitalised non-ICU ward and ICU ward.DesignCross-sectional survey using binomial mixed models.SettingCOVID-19-positive cases diagnosed by reverse transcription–PCR of municipalities located in Paraná State.PatientsCases of anonymous datasets of electronic medical records from 1 April 2020 to 31 December 2020.Primary and secondary outcome measuresThe best prediction factors were chosen based on criteria after a stepwise analysis using multicollinearity measure, lower Akaike information criterion and goodness-of-fit χ2tests from univariate to multivariate contexts.ResultsMale sex was associated with increased mortality among non-hospitalised patients (OR 1.76, 95% CI 1.47 to 2.11) and non-ICU patients (OR 1.22, 95% CI 1.05 to 1.43) for symptoms and for comorbidities (OR 1.89, 95% CI 1.59 to 2.25, and OR 1.30, 95% CI 1.11 to 1.52, respectively). Higher mortality occurred in patients older than 35 years in non-hospitalised (for symptoms: OR 4.05, 95% CI 1.55 to 10.54; and for comorbidities: OR 3.00, 95% CI 1.24 to 7.27) and in hospitalised over 40 years (for symptoms: OR 2.72, 95% CI 1.08 to 6.87; and for comorbidities: OR 2.66, 95% CI 1.22 to 5.79). Dyspnoea was associated with increased mortality in non-hospitalised (OR 4.14, 95% CI 3.45 to 4.96), non-ICU (OR 2.41, 95% CI 2.04 to 2.84) and ICU (OR 1.38, 95% CI 1.10 to 1.72) patients. Neurological disorders (OR 2.16, 95% CI 1.35 to 3.46), neoplastic (OR 3.22, 95% CI 1.75 to 5.93) and kidney diseases (OR 2.13, 95% CI 1.36 to 3.35) showed the majority of increased mortality for ICU as well in the three levels of severity jointly with heart disease, diabetes and CPOD.ConclusionsThese findings highlight the importance of the predictor’s assessment for the implementation of public healthcare policy in response to the COVID-19 pandemic, mainly to understand how non-pharmaceutical measures could mitigate the virus impact over the population.
Perceived quality of care among households ever enrolled in a community-based health insurance scheme in two districts of northeast Ethiopia: a community-based, cross-sectional study
Authors: Hussien Mohammed , Azage Muluken , Bayou Negalign Berhanu 
Published: October 2022

ObjectivesTo examine how clients perceived the quality of healthcare they received and identify associated factors both at the individual and facility levels.DesignA community-based, cross-sectional study.SettingTwo rural districts of northeast Ethiopia, Tehulederie and Kallu.Participants1081 rural households who had ever been enrolled in community-based health insurance and visited a health centre at least once in the previous 12 months. Furthermore, 194 healthcare providers participated in the study to provide cluster-level data.Outcome measuresThe outcome variable of interest was the perceived quality of care, which was measured using a 17-item scale. Respondents were asked to rate the degree to which they agreed on 5-point response items relating to their experiences with healthcare in the outpatient departments of nearby health centres. A multilevel linear regression analysis was used to identify predictors of perceived quality of care.ResultsThe mean perceived quality of care was 70.28 (SD=8.39). Five dimensions of perceived quality of care were extracted from the factor analysis, with the patient-provider communication dimension having the highest mean score (M=77.84, SD=10.12), and information provision having the lowest (M=64.67, SD=13.87). Wealth status, current insurance status, perceived health status, presence of chronic illness and time to a recent health centre visit were individual-level variables that showed a significant association with the outcome variable. At the cluster level, the work experience of healthcare providers, patient volume and an interaction term between patient volume and staff job satisfaction also showed a significant association.ConclusionsMuch work remains to improve the quality of care, especially on information provision and access to care quality dimensions. A range of individual-level and cluster-level characteristics influence the perceived quality of care. For a better quality of care, it is vital to optimise the patient-provider ratio and enhance staff job satisfaction.
Effect of structured rehabilitation versus non-structured rehabilitation following non-surgical management of displaced proximal humerus fractures: a protocol for a randomised clinical trial
Authors: Liaghat Behnam , Brorson Stig 
Published: October 2022

IntroductionAn increasing number of patients with displaced proximal humerus fractures (PHF) are being offered non-surgical treatment, including short immobilisation and structured rehabilitation. There are no randomised controlled trials (RCTs) comparing structured rehabilitation with non-structured rehabilitation to investigate the benefits of structured rehabilitation.Methods and analysisIn this RCT, patients with a displaced PHF will be assessed for eligibility at a Danish university outpatient clinic. Patients with competing injuries or patients offered surgery will be excluded, and randomisation will be 1:1. All patients will receive standard orthopaedic follow-up, including 14-day postinjury immobilisation, and advice about returning to activities of daily living before being allocated to structured rehabilitation in the municipalities or non-structured rehabilitation. The primary outcome is the between-group difference in the Oxford Shoulder Score (0–48 points, 48=best, minimal clinically important difference=10) at 6 months. A sample size of 60 patients will allow us to show a 10-point difference with 80% power.Ethics and disseminationFunded by Department of Orthopaedics, Zealand University Hospital (grant number N/A) and Region Zealand Health Science Research Foundation (R32-A1108-B14), 14 January 2022; The Ethics committee in Region Zealand approved (EMN-2022-02449), 8 April 2022. The site opened on 5 May 2022, and the final results will be updated on trial registries, submitted to a peer-reviewed journal, and inform rehabilitation strategies after displaced PHFs. Protocol version 1, 21 April 2022.Trial registration numberNCT05302089.
Prevalence of pneumonia and malnutrition among children in Jigawa state, Nigeria: a community-based clinical screening study
Authors: King Carina , Siddle Morgan , Adams Osebi , Ahmar Samy , Ahmed Tahlil , Bakare Ayobami Adebayo , Bakare Damola , Burgess Rochelle Ann , Colbourn Tim , McCollum Eric D , Olowookere Temitayo , Salako Julius , Uchendu Obioma , Graham Hamish R , Falade Adegoke Gbadegesin 
Published: October 2022

ObjectiveTo estimate the point prevalence of pneumonia and malnutrition and explore associations with household socioeconomic factors.DesignCommunity-based cross-sectional study conducted in January–June 2021 among a random sample of households across all villages in the study area.SettingKiyawa Local Government Area, Jigawa state, Nigeria.ParticipantsChildren aged 0–59 months who were permanent residents in Kiyawa and present at home at the time of the survey.Main outcome measuresPneumonia (non-severe and severe) defined using WHO criteria (2014 revision) in children aged 0–59 months. Malnutrition (moderate and severe) defined using mid-upper arm circumference in children aged 6–59 months.Results9171 children were assessed, with a mean age of 24.8 months (SD=15.8); 48.7% were girls. Overall pneumonia (severe or non-severe) point prevalence was 1.3% (n=121/9171); 0.6% (n=55/9171) had severe pneumonia. Using an alternate definition that did not rely on caregiver-reported cough/difficult breathing revealed higher pneumonia prevalence (n=258, 2.8%, 0.6% severe, 2.2% non-severe). Access to any toilet facility was associated with lower odds of pneumonia (aOR: 0.56; 95% CI: 0.31 to 1.01). The prevalence of malnutrition (moderate or severe) was 15.6% (n=1239/7954) with 4.1% (n=329/7954) were severely malnourished. Being older (aOR: 0.22; 95% CI: 0.17 to 0.27), male (aOR: 0.77; 95% CI: 0.66 to 0.91) and having head of compound a business owner or professional (vs subsistence farmer, aOR 0.71; 95% CI: 0.56 to 0.90) were associated with lower odds of malnutrition.ConclusionsIn this large, representative community-based survey, there was a considerable pneumonia and malnutrition morbidity burden. We noted challenges in the diagnosis of Integrated Management of Childhood Illness-defined pneumonia in this context.
Humans not heroes: Canadian emergency physician experiences during the early COVID-19 pandemic
Authors: Tran Anna , Wallner Clare , de Wit Kerstin , Gérin-Lajoie Caroline , Ritchie Kerri , Mercuri Mathew , Clayton Natasha , Boulos Mary , Archambault Patrick , Schwartz Lisa , Gray Sara , Chan Teresa Man-Yee 
Published: October 2022

BackgroundThe pandemic has upended much clinical care, irrevocably changing our health systems and thrusting emergency physicians into a time of great uncertainty and change. This study is a follow-up to a survey that examined the early pandemic experience among Canadian emergency physicians and aimed to qualitatively describe the experiences of these physicians during the global pandemic. The study was conducted at a time when Canadian COVID-19 case numbers were low.MethodsThe investigators engaged in an interview-based study that used an interpretive description analytic technique, sensitised by the principles of phenomenology. One-to-one interviews were conducted, transcribed and then analysed to establish a codebook, which was subsequently grouped into key themes. Results underwent source triangulation (with survey data from a similar period) and investigator-driven audit trail analysis.ResultsA total of 16 interviews (11 female, 5 male) were conducted between May and September 2020. The isolated themes on emergency physicians’ experiences during the early pandemic included: (1) disruption and loss of emergency department shift work; (2) stress of COVID-19 uncertainty and information bombardment; (3) increased team bonding; (4) greater personal life stress; (5) concern for patients’ isolation, miscommunication and disconnection from care; (6) emotional distress.ConclusionsCanadian emergency physicians experienced emotional and psychological distress during the early COVID-19 pandemic, at a time when COVID-19 prevalence was low. This study’s findings could guide future interventions to protect emergency physicians against pandemic-related distress.