bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluasi Status Reproduksi Sapi Hasil Persilangan Peranakan Ongole dengan Bali
Authors: Efendy Jauhari , Prihandini Peni Wahyu , Sulistya Tri Agus , Primasari Almira 
Published: January 2022

ABSTRACT. Tujuan penelitian untuk mengetahui status reproduksi hasil persilangan sapi peranakan ongole (PO) dan sapi bali (yang selanjutnya dinamakan sapi POBA) jantan dan betina melalui beberapa kegiatan lapang. Penelitian ini bersifat non eksperimental yang dilakukan secara eksploratif; menggunakan 20 ekor sapi berumur antara 32 sampai 36 bulan. Parameter yang diamati meliputi kualitas semen, kondisi organ reproduksi sapi betina dan angka kebuntingan. Hasil penelitian menunjukkan, kualitas semen sapi POBA rendah atau jelek berdasarkan hasil analisis secara mikroskopis maupun makroskopis; namun memiliki libido yang cukup tinggi yaitu rata-rata sekitar 4 menit 25 detik dari mulai mengendus atau didekatkan dengan ternak pemancing (teaser) sampai ejakulasi. Secara umum kondisi organ reproduksi sapi POBA betina normal, sehingga siap dijadikan indukan yang produktif. Sebanyak 66,67% menunjukkan perilaku estrus yang tampak terutama keluar lendir yang terlihat jelas menggantung di bibir vagina bahkan diantaranya mengejar dan/atau menaiki sapi-sapi lain. Namun hasil pemeriksaan kebuntingan (PKB) melalui palpasi rektal menunjukkan tidak ada sapi betina yang bunting. Dapat disimpulkan bahwa sapi POBA jantan infertil, yang diindikasikan melalui hasil pemeriksaan semen dan tidak adanya sapi betina yang berhasil bunting melalui perkawinan alam selama 3 (tiga) bulan. Sedangkan sapi betina POBA memiliki organ reproduksi normal serta menunjukkan ekspresi estrus yang baik. (The evaluation of cattle reproduction status between crosses Ongole Crossbreed with Bali cows) ABSTRAK. The purpose of this research was to determine the reproductive status of the crossbred PO and Bali cattle (hereinafter referred to as POBA cattle) through several field activities. This research is non-experimental and carried out exploratory using 20 cattle aged 32 to 36 months. Parameters observed included semen quality, cows' reproductive organ condition, and pregnancy rate. The quality of POBA bulls semen was low or bad as indicated by the results of microscopic and macroscopic analysis; but had pretty high libido, which was an average of about 4 minutes and 25 seconds, starting to sniff or being brought near to teaser until ejaculation. In general, the reproductive organs of POBA cows were normal so that they were ready to become productive sires. As many as 66.67% showed estrus behavior, especially visible mucus that was hanging on the lips of the vagina, even among them chasing and/or riding other cattle. However, the results of pregnancy examination through rectal palpation showed that there were no pregnant cows. It can be concluded that POBA bulls are infertile, which was indicated by the results of semen examination and the absence of successfully conceived cows through natural mating for 3 (three) months. Meanwhile, POBA cows have normal reproductive organs and show good estrus expression.
Aplicación de altas presiones y otras tecnologías en frutas como alternativa de tratamientos térmicos convencionales
Authors: Martinez Giron Jader , Figueroa Sepúlveda Katherine , Castillo Robles Nelly Zarith 
Published: January 2022

En la actualidad la industria alimentaria busca ofrecer productos alimentarios frescos pero a su vez que tengan una vida útil prolongada. Existen varias técnicas que requieren tratamiento térmico las cuales permiten aumentar la vida útil de los alimentos pero estas pueden afectar la calidad final del producto. La alta presión hidrostática y la homogeneización por altas presiones son nuevas técnicas no térmicas que permiten actuar sobre los alimentos a temperaturas de proceso bajas alargando la vida útil y conservando la calidad nutricional. La alta presión hidrostática se ha aplicado en diferentes frutas mínimamente procesadas para conservar su frescura y propiedades nutricionales entre ellas los duraznos, el mango, las cerezas, las fresas, la pulpa de naranja, el melón, la chirimoya y las aceitunas donde se ha determinado que esta técnica conserva mejor las propiedades de estos materiales vegetales respecto a tratamientos térmicos convencionales. En cuanto a la homogeneización por alta presión se ha aplicado principalmente en jugos de manzana, fresa, mango, sandía, toronja y zumo de naranja obteniendo una buena inactivación de microorganismos y una mejor conservación de compuestos bioactivos, sin afectar las propiedades nutricionales y funcionales.
A táplálkozás és testmozgás kiemelkedő szerepe az egészséges életmódban
Authors: Szabó Katalin , Kinczel Antonia , Molnár Anikó , Müller Anetta 
Published: January 2022

Az életmóddal összefüggő betegségek, mint például a 2-es típusú cukorbetegség, az elhízás, a szív- és érrendszeri vagy stresszel összefüggő betegségek, illetve a csontritkulás mindenki számára jól ismertek, és megelőzésükben vagy kialakulásukban az életmódbeli elemek, mint például az étrend vagy a testmozgás kulcsszerepet játszanak. Ahhoz, hogy megelőzzük ezen fent említett betegségek kialakulását, kellő figyelmet kell fordítanunk az egészséges életmódra és a prevencióra. A mai modern világunkban már rengeteg olyan ismerettel rendelkezünk, amelyek nagyban hozzájárulnak az említett betegségek megelőzéséhez, ennek ellenére még mindig sokan küzdenek velük. Fontos tényező, hogy a rendszeres testmozgás és az egészséges táplálkozás hozzájárul az egészségesebb életmód kialakításához, és védelmet nyújt a betegségek széles skálájával szemben.
JEL-kódok: I10, I12, I19
The system of indicators of behavioral risk factors in Russia at the national and regional levels
Authors: Zubkova T. S. , Zamiatnina E. S. , Khalturina D. A. 
Published: January 2022

Introduction. Behavioral risk factors are associated with 47% of all-cause mortality in Russia.The goal of this study was to assess and to select the available data sources on the burden of behavioral risk factors in Russia and its regions.Methods included collection and systematization of medical, demographic and survey which reflected the burden of behavioral risk factors in Russia.Results. The spectrum of sources of the data on behavioral risk factors among adults in Russia has significantly expanded in recent years. Rosstat agency provided regional survey data on prevalence of consumption of tobacco and other nicotine-containing products, physical activity, overweight and obesity. The survey results may underestimate alcohol and tobacco consumption due to the sensitivity of these questions. Therefore, the use of morbidity and mortality data is needed well. Detailed regional data on food product consumption in Russia are available, but the list of food groups needs to be updated to reflect current scientific knowledge. At the same time, there is no monitoring of the consumption of table salt and iodine by the Russian citizens. The data from Rosstat surveys on physical activity is available by the regions, and it provides more reliable results in comparison with the reports of sports organizations. Monitoring of behavioral risk factors among children and adolescents in Russia has yet to be organized.Conclusions. A number of data sources have been identified that can be used to assess the burden of behavioral risk factors in Russia and the regions, and ways to improve such monitoring are proposed.
Risk of Revision After Arthroplasty Associated with Specific Gene Loci
Authors: Brüggemann Anders , Eriksson Niclas , Michaëlsson Karl , Hailer Nils P. 
Published: January 2022

Background:
The risk of revision surgery following total joint arthroplasty (TJA) may be influenced by genetic factors. Therefore, we sought to identify genetic variants associated with the risk of revision surgery in a genomewide association study.

Methods:
We investigated a cohort of 1,130 twins from the Swedish Twin Registry treated with TJA. During a mean of 9.4 years of follow-up, 75 individuals underwent revision surgery for aseptic loosening (the primary outcome) and 94, for any reason (the secondary outcome). Genetic information was collected using the Illumina OmniExpress and PsychArray panels, and the Haplotype Reference Consortium served as the reference for gene imputation. Adjusted Cox regression models were fitted to calculate hazard ratios (HRs) with 95% confidence intervals (CIs).

Results:
Nine single-nucleotide polymorphisms (SNPs) reached genomewide significance for aseptic loosening. The first SNP, rs77149046, located in the endosome-lysosome associated apoptosis and autophagy regulator family member 2 (ELAPOR2) gene, conferred an HR of 5.40 (CI, 3.23-9.02; p = 1.32×10−10), followed by 4 SNPs within the region coding for sodium-dependent taurine and beta-alanine transporter (SLC6A6), with HRs ranging from 3.35 to 3.43. The sixth SNP, rs7853989 (HR, 3.46; CI, 2.33-5.13; p = 6.91×10−10), was located in a region coding for the ABO blood group system. This SNP has been described as predictive for blood type B. Seven significant SNPs were found for the risk of revision for any reason, with the first 4 again being located in the SLC6A6 region. The leading SNP, rs62233562, conferred an HR of 3.11 (CI, 2.19-4.40; p = 1.74×10−10) for revision surgery. Similar HRs were found for SNPs 3:14506680 (p = 1.78×10−10), rs2289129 (p = 1.78×10−10), and rs17309567 (p = 3.16×10−10). The fifth SNP, rs11120968, was located in the calmodulin-binding transcription activator 1 (CAMTA1) gene (HR, 2.34; CI, 1.74-3.13, p = 1.45×10−8).

Conclusions:
We identified 12 unique SNPs associated with an increased risk of revision surgery. Among these, 2 were in ELAPOR2, which is closely linked to bone formation. Another SNP is located in a gene region encoding for the ABO system, which merits further studies of causal relationships.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Nonlinear suboptimal attitude control law for near-space hypersonic vehicle: Eigenvalue analysis and weight matrices design
Authors: Mi Peichao , Wu Qingxian , Wang Yuhui 
Published: January 2022

Abstract
This paper considers a nonlinear suboptimal control problem for a near-space hypersonic vehicle's (NSHV's) attitude dynamics. The least-square and stable manifold methods first solve an unconstrained approximately optimal control law corresponding to the nonlinear attitude model. Then, to further meet the dynamic performance requirement of the attitude control system, a novel strategy based on the Koopman operator, symplectic geometric theory, and the stable manifold theorem is proposed to approximate the eigenvalues of the closed-loop nonlinear unconstrained approximated optimal control system. The weight matrices in the optimal performance index, which directly determine the output responses of the nonlinear attitude dynamics, can be appropriately designed according to the eigenvalues. The final control law considers the actuator constraints. The NSHV's closed-loop attitude control system is proved to be locally exponentially stable, and the suboptimality of the control law is analyzed. Numerical simulation demonstrates the effectiveness of the proposed scheme.
Mathematical Modelling And Simulation of CH3NH3Pb(I1-Xbrx)3 Based Perovskite Solar Cells For High Efficiency
Authors: Sharma Divya , Mehra Rajesh , Raj Balwinder 
Published: January 2022

Abstract
Mathematical modelling can offer the physical intuitions about the charge transport process inside a solar cells and provide the various elements affecting their performance. In the present paper, (CH3NH3Pb(I1-xBrx)3 based various perovskite solar cells have been mathematically simulated deploying SCAPS simulator. Various Hole Transport layers (HTLs) based on thickness, total defect density and donor density of mixed halide perovskite have been compared using Cd1-xZnxS as an Electron Transport Layer (ETL). Amongst the proffered HTLs, P3HT [Poly(3-hexylthiophene)] executed better and exhibited the PCE of 28.28%. During the simulation, mixed halide perovskite layer with thickness of 700 nm has been found suitable for the effective solar cell design. These mathematically simulated outcomes indicate the optimum efficiency of the solar cell that may further be prompted to design the extremely high efficient solar cells.
Easily Misdiagnosed cblC Deficiency in Adolescents: the Clinical and Metabolic Studies
Authors: Chen Zhehui , Dong Hui , Liu Yupeng , He Ruxuan , Song Jinqing , Jin Ying , Li Mengqiu , Liu Yi , Liu Xueqin , Yan Hui , Qi Jianguang , Wang Fang , Xiao Huijie , Zheng Hong , Kang Lulu , Li Dongxiao , Zhang Yao , Yang Yanling 
Published: January 2022

Abstract
Purpose: Adolescents are easily attacked by potential inherited metabolic disorders. cblC deficiency is the most common type of methylmalonic aciduria in China. The late-onset patients present with varied non-specific symptoms and usually being misdiagnosed. The purpose of this study is to investigate the clinical features of patients with adolescence-onset cblC deficiency and explore the prevention and control strategies. Methods: Fifty-seven patients (34 males and 23 females) with adolescence-onset cblC deficiency were admitted in our clinic from 2002 to September 2021. The diagnosis was confirmed by metabolic and genetic tests. The clinical and biochemical features, disease triggers, outcome and genotypes-phenotypes correlation were examined.Results: The onset ages ranged from 10 to 25 years old (median age was 12 years). 16 cases (28.0%) presented with symptoms after infection or sports training. 46 patients (80.7%) had neuropsychiatric diseases. 14 patients (24.6%) displayed cardiovascular diseases. Five cases (8.9%) showed pulmonary hypertension. Renal damage was observed in seven cases (12.3%). 23 mutations were identified from the MMACHC gene of 57 patients. 37 patients demonstrated c.482G>A (64.9%) and 16 cases had c.609G>A (26.3%). Among 13 patients that exhibited spastic paraplegia as a main manifestation, 10 patients had c.482G>A (76.9%). Five patients presented with psychotic disorders and spastic paraplegia with c.482G>A. All patients improved after metabolic treatment with cobalamin, L-carnitine, and betaine. 30 school-aged patients returned to school. Two patients were married and had healthy babies.Conclusion: Patients with adolescence-onset cblC deficiency presented with varied neuropsychiatric symptoms or multiple organ damage. Metabolic studies and individualized treatment are keys to improve the outcome of the patients.
A Multilevel Analysis of Trends and Predictors Associated with Teenage Pregnancy and Early Motherhood in Zambia (2001 - 2018)
Authors: Phiri Million , Kasonde Mwewa E. , Moyo Nkuye , Sikaluzwe Milika , Simona Simona 
Published: January 2022

Abstract
IntroductionTeenage pregnancy remains a major social and public health challenge in developing countries especially sub-Saharan Africa (SSA) where prevalence rates are still increasing. Even if considerable effort has been made over the years to study determining factors of teenage pregnancy in SSA, few studies have looked at the trends and associated factors over a longer period. Furthermore, no known study has focussed on both individual and contextual factors influencing teenage pregnancy in Zambia. This study, thus sought to fill this gap in knowledge by simultaneously investigating trends of teenage pregnancy and early motherhood as well as its individual and contextual determining factors. MethodsA total pooled weighted sample of 10,010 teenagers (in the age group 15 to 19) from four waves of the Zambia Demographic and Health Surveys (ZDHS) were extracted. Using bivariate analysis, we investigated the trends of teenage pregnancy between 2001 and 2018. Separate multilevel logistic regression models were fitted on pooled teenage pregnancy data in relation to several individual and contextual level factors. Both fixed and random effects were produced. Parameter estimates were produced using Bayesian Markov chain Monte Carlo (MCMC) Methods in BRMS.ResultsResults show that the trends of teenage pregnancy in Zambia have shown an overall decrease of 2% between 2001 and 2018. Almost all the socioeconomic and demographic variables were consistently associated with teenage pregnancy (p < 0.001) in a bivariate analysis across the four ZDHS waves. In multilevel analysis, the odds of being pregnant were higher for teenagers who were aged between 18 and 19 years (AOR = 2.57, 95% CI: 2.20-2.98), employed (AOR= 1.24, 95% CI: 1.06-1.46) married (AOR =8.33, 95% CI: 6.84-10.26) and those with knowledge of fertile period (AOR=1.69, 95% CI: 1.43-2.00). On the other hand, being in higher wealth quintile, 15-17 years of age, exposure to family planning messages and delayed sexual debut were associated with decreased odds of early teenage pregnancy. ConclusionThe study shows that early pregnancy remains a social and public health challenge in Zambia as the country has seen little decrease in the prevalence over the years under consideration. Factors associated with teenage pregnancy and early motherhood include age, marital status, and employment, knowledge of fertility period, wealth quintile, sexual debut and exposure to mass-media family planning messaging. Concerted effort must be made to improve literacy levels, reduce poverty and enhance sexual health promotion through the mass media in view of cultural norms, which may prevent parents and children from discussion sexual education topics thus exacerbate the vice.
Ultrasound Guided Vascular Access in The Neonatal Intensive Care Unit: A Nationwide Survey
Authors: Oulego-Erroz Ignacio , Alonso-Ojembarrena Almudena , Aldecoa-Bilbao Victoria , Bravo Maria Carmen , Montero-Gato Jon , Mosqueda-Peña Rocio , Rodríguez-Núñez Antonio 
Published: January 2022

Abstract
Ultrasound guided percutaneous vascular access (USG-PVA) is recommended by international practice guidelines but information regarding its use in the neonatal intensive care unit (NICU) is lacking. Our objective was to assess neonatologist’s perceptions and current implementation of USG-PVA in Spain. This was a nationwide online survey. The survey was composed of 37 questions divided in 4 domains: 1) neonatologist’s background, 2) NICU characteristics, 3) personal perspectives about USG-PVA and clinical experience in USG-PVA. One hundred and eighty survey responses from 59 NICUs (62% of Spanish NICUs) were analyzed. Most neonatologist (81%) perceive that competence in USG-PVA is indispensable or very useful in clinical practice. However, 64 (35.5%) have never used USG-PVA in real patients. Among neonatologists with some experience in USG-PVA most perform less than 5 procedures per year (59% in venous access and 80% in arterial access) and a 38% and 60% have never used USG for venous and arterial access respectively in very low birth weight infants (VLBWI). Spanish neonatologists report that residents/fellows training in USG-PVA is absent (52.2%) or unstructured (32%) in their units. The lack of adequate training is identified by a 60% of neonatologists as the most important barrier for implementation of USG-PVA and 87% would recommend that future neonatologists receive formal training. In conclusion, Spanish neonatologists perceive that USG-PVA is important in clinical practice but, currently these techniques are largely underused. Our results indicate that specific training in USG-PVA should be implemented in the NICU.
Dearomative [4 + 3] cycloaddition of furans with vinyl-N-triftosylhydrazones by silver catalysis: stereoselective access to oxa-bridged seven-membered bicycles
Authors: Liu Zhaohong , Yang Yong , Jiang Xinyu , Song Qingmin , Zanoni Giuseppe , Liu Shaopeng , Bi Xihe 
Published: January 2022

Abstract
The first example of dearomative [4 + 3] cycloaddition between furans and vinyl-N-sulfonylhydrazones as vinylcarbene precursors is reported. The merger of silver catalysis and easily decomposable vinyl-N-triftosylhydrazones enabled the efficient synthesis of a variety of skeletally and functionally diverse oxa-bridged seven-membered bicyclic compounds with complete and predictable stereoselectivity. The combination of experimental studies and DFT calculations disclosed that the silver-catalyzed reaction proceeds via a concerted [4 + 3] cycloaddition mechanism, rather than the generally accepted cyclopropanation / Cope rearrangement pathway by rhodium catalysis.
Effects of Mesoscale Eddies On Intraseasonal Variability of Intermediate Water East of Taiwan
Authors: Ren Qiang , Yu Fei , Nan Feng , Li Yuanlong , Wang Jianfeng , Liu Yansong , Chen Zifei 
Published: January 2022

Abstract
The variability of intermediate water (IW) east of Taiwan was investigated utilizing 17 months of long-term, continuous and synchronous measurements of temperature, salinity and current from mooring sites deployed at 122ºE/23ºN from January 2016 to May 2017. For the first time, we prove that the intraseasonal variability in the IW within significant periods of ~80 days was caused by mesoscale eddies propagating westward from the Subtropic Counter Current (STCC) area. The correlation coefficients between sea level anomalies (SLAs) and the Kuroshio, and between SLAs and the minimum salinity in the intermediate layer, were 0.63 and 0.52, respectively. The anticyclonic (cyclonic) eddies from the STCC, increased (decreased) the speed of the Kuroshio as well as increase (decrease) the temperature and salinity in the 400–600 m in east of Taiwan. Combines Archiving, Validation and Interpretation of Satellite Oceanographic (AVISO) products data, showed that temperature and salinity increased (decreased) in the intermediate layer due to the downward (upward) vertical movement of the water mass by anticyclonic (cyclonic) eddies. Anticyclonic eddies strengthened the Kuroshio and benefitted SCSIW flowing through the Luzon Strait to enhance salinity, while cyclonic eddies weakened the Kuroshio and favored relatively low-salt NPIW, in the area east of Taiwan.