bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diversification linked to larval host plant in the butterflyEumedonia eumedon
Authors: Hinojosa Joan C. , Montiel‐Pantoja Cecilia , Sanjurjo‐Franch Miguel , Martínez‐Pérez Isabel , Lee Kyung Min , Mutanen Marko , Vila Roger 
Published: October 2022

AbstractIt is widely accepted that the relationship between phytophagous insects and their host plants influences insect diversification. However, studies addressed at documenting host‐associated genetic differentiation (HAD) and the mechanisms that drive reproductive isolation in host‐associated lineages (or host races) are still scarce relative to insect diversity. To uncover further evidence on the HAD processes in Lepidoptera, we investigated the genetic structure of the geranium argus butterfly (Eumedonia eumedon) and tested for isolation by ecology (IBE) vs. isolation by distance (IBD). Genomic data revealed an array of host races (three of them in the same mountain range, the Cantabrian Mountains, northern Iberia) at apparently distinct levels of reproductive isolation. We found a pattern of IBE mediated by HAD at both local and European scales, in which genetic differentiation between populations and individuals correlated significantly with the taxonomic relatedness of the host plants. IBD was significant only when considered at the wider European scale. We hypothesize that, locally, HAD betweenGeranium‐feeding populations was caused (at least partially) by allochrony, that is via adaptation of adult flight time to the flowering period of each host plant species. Nevertheless, the potential reproductive isolation between populations usingErodiumand populations usingGeraniumcannot be explained by allochrony or IBD, and other mechanisms are expected to be at play.
Annotated translation of Georg Meissner's first description of the submucosal plexus
Authors: Neckel Peter H. 
Published: October 2022

AbstractBackgroundThe discovery and detailed descriptions of the enteric nervous system dates back only ˂200 years. The 19th century was a golden age of histological, morphological, and physiological breakthroughs propelled by technological advances in microscopy, electricity, and scientific methodology. As a matter of fact, German‐speaking scientists were highly successful during this period as can still be appreciated by the sheer number of German eponyms in anatomy. Therefore, the main language in scientific literature of this field was German at the time, thus, limiting the accessibility to the publications and scientific discussions from back then for the broader English‐speaking scientific community today.PurposeHere, an annotated translation of Meissner's first description of the submucosal plexus is provided along with a short biography of Georg Meissner and a review of the scientific literature and controversy surrounding his discovery.
SnRK2.4‐mediated phosphorylation of ABF2 regulates ARGININE DECARBOXYLASE expression and putrescine accumulation under drought stress
Authors: Song Jie , Sun Peipei , Kong Weina , Xie Zongzhou , Li Chunlong , Liu Ji‐Hong 
Published: October 2022

Summary

Arginine decarboxylase (ADC)‐mediated putrescine (Put) biosynthesis plays an important role in plant abiotic stress response. SNF1‐related protein kinases 2s (SnRK2s) and abscisic acid (ABA)‐response element (ABRE)‐binding factors (ABFs), are core components of the ABA signaling pathway involved in drought stress response. We previously reported that ADC of Poncirus trifoliata (PtrADC) functions in drought tolerance. However, whether and how SnRK2 and ABF regulate PtrADC to modulate putrescine accumulation under drought stress remains largely unclear.

Herein, we employed a set of physiological, biochemical, and molecular approaches to reveal that a protein complex composed of PtrSnRK2.4 and PtrABF2 modulates putrescine biosynthesis and drought tolerance by directly regulating PtrADC.

PtrABF2 was upregulated by dehydration in an ABA‐dependent manner. PtrABF2 activated PtrADC expression by directly and specifically binding to the ABRE core sequence within its promoter and positively regulated drought tolerance via modulating putrescine accumulation. PtrSnRK2.4 interacts with and phosphorylates PtrABF2 at Ser93. PtrSnRK2.4‐mediated PtrABF2 phosphorylation is essential for the transcriptional regulation of PtrADC. Besides, PtrSnRK2.4 was shown to play a positive role in drought tolerance by facilitating putrescine synthesis.

Taken together, this study sheds new light on the regulatory module SnRK2.4‐ABF2‐ADC responsible for fine‐tuning putrescine accumulation under drought stress, which advances our understanding on transcriptional regulation of putrescine synthesis.
Validation of the food allergy quality of life questionnaire series in Chinese families with food‐allergic children
Authors: Leung Agnes Sze Yin , Cheng Nam Sze , Li Rebecca Ming Yan , Li Pui Fung , Lee Yat Laam , Fu Tik Wai , Flokstra‐de Blok Bertine , Leung Ting Fan 
Published: October 2022

AbstractBackgroundAnxiety from accidental exposure and vigilant dietary monitoring impair the quality of life (QoL) of food‐allergic patients. A comprehensive food allergy‐specific questionnaire allows patients to accurately report their QoL. This study validated the Food Allergy Quality of Life Questionnaire (FAQLQ) series and assessed the QoL of Chinese food‐allergic patients and their caregivers.MethodsFAQLQ series developed by EuroPrevall consists of four separate questionnaires for parents, children, adolescents and adults. All questionnaires were translated into traditional Chinese by standard forward and backward methods. A cross‐sectional study was conducted on food‐allergic patients and children's parents using an age‐appropriate questionnaire. The performance indices of FAQLQ and their correlation with independent measures of food allergy were analyzed, and factor analysis was performed to confirm the factor structure of FAQLQ questionnaires.ResultsCross‐sectional validation was performed on 214 participants, with 40 reassessed for test–retest reliability. Overall scores for the FAQLQ series had good internal consistency with Cronbach's α ≥.90. Good construct validity was demonstrated by correlations between FAQLQ‐Parent Form, FAQLQ‐Child Form, FAQLQ‐Teenager Form, FAQLQ‐Adult Form and Food Allergy Independent Measure (FAIM) scores, except in 0‐ to 3‐year‐old children. Test–retest analyses revealed a significant correlation between total FAQLQ score, parent‐reported FAIM and food anxiety domain in 4–6 years, and between total score and FAIM in 7–12 years. Exploratory factor analysis categorized items in the FAQLQ series into three to four domains.ConclusionFAQLQ series provide a valid and reliable measure for QoL in Chinese food‐allergic patients and caregivers, except for parents of children aged 0–3 years. Items for all FAQLQ questionnaires are categorized into different functional domains in our population.
Exploring the ethical complexity of pediatric organ transplant candidates and COVID‐19 vaccination: Tensions between autonomy and beneficence, children and parents
Authors: Lara Carrion Libia , Bramstedt Katrina A. 
Published: October 2022

AbstractBackgroundPOT is emotionally sensitive due to cohort vulnerability, their lack of decisional capacity, and waitlist mortality. The COVID‐19 pandemic has added complexity to the setting of pediatric transplantation, as well as living donation, due to tensions about COVID‐19 vaccination for recipients, donors, and parent‐caregivers.MethodsIn the context of COVID‐19 vaccination, two ethicists present four pediatric donation and transplant dilemmas for ethical exploration and offer guidance to clinical teams, noting that mandates are controversial, and there is no global harmonization regarding requirements.ResultsAs with all vaccinations, they are a tool of organ stewardship aimed to optimize outcomes and, in the setting of pediatrics, ensure optimal caregiving for these vulnerable recipients. Current evidence supports the ethical permissibility of COVID‐19 vaccination mandates for transplant candidates aged 6 months and older.ConclusionOur guidance considers the tensions of autonomy and beneficence and the ethical duty of organ stewardship. The harms of being unvaccinated and risking the harms of COVID‐19 and long‐COVID post‐transplant support the ethical permissibility of vaccination mandates in countries where the vaccine has pediatric regulatory approval.
Optimization of recovery and maturation methods for cumulus‐oocyte complexes in jennies
Authors: Dai Shizhen , Di Zhengyang , Li Nan , Zeng Shenming 
Published: October 2022

AbstractEmbryo production in donkeys is inefficient compared with that in other livestock. Obtaining a sufficient number of MII oocytes is the first step to solving this problem. In this study, the number, morphology and maturation rates of cumulus‐oocyte complexes (COCs) obtained from abattoir‐derived ovaries or live jennies were compared. The diameter of follicles from abattoir‐derived ovaries was measured and divided into group 1 (2–6 mm), group 2 (6–10 mm), group 3 (10–20 mm), group 4 (20–28 mm) and group 5 (>28 mm). The results showed that the number of follicles per ovary in group 2 (3.6 ± 0.28) and 3 (4.2 ± 0.90) was higher than that in the other groups (p < .05). The recovery rate in group 3 was higher than group 1 (48.8% vs. 26.8%, p = .00), but lower than group 5 (48.8% vs. 76.5%, p = .025). The percentage of grade A COCs in group 3 was higher than group 2 (59.3% vs. 39.5%, p = .00) and group 1 (59.3% vs. 26.7%, p = .00). Moreover, the percentage of grade A COCs in group 4 (55.0%, p = .710) and group 5 (46.2%, p = .351) was reduced compared with that in group 3. From the above results, the developing follicles (group ovum pick‐up [OPU], 10–20 mm) and preovulation follicles (group OPU‐Preov, >35 mm) were aspirated from live jennies using OPU. Although there was no difference in the recovery rates of COCs between group 3 and OPU (48.8% vs. 43.0%, p = .184), the percentage of grades A COCs in group OPU was higher than group 3 (72.5% vs. 59.3%, p = .036). There was no difference in the maturation rate between group 3 and OPU (60.3% vs. 69.3%, p = .171) after the COCs matured in vitro. The rates of recovery (72.2%) and maturation (92.3%) in group OPU‐Preov were higher than those in other groups (p < .05). Moreover, the effects of maturation time and serum type on maturation rates were evaluated in groups B44 (44 h, FBS), B36 (36 h, FBS) and D44 (44 h, foetal donkey serum, FDS). These results indicated that the maturation rate in group B36 was lower than group B44 (13.1% vs. 47.0%, p = .00) and group D44 (13.1% vs. 53.3%, p = .00). In conclusion, the quality of donkey COCs from OPU was higher than that from abattoir‐derived ovaries, the suitable time of donkey in vitro maturation (IVM) was 44 h, and FBS could be replaced with FDS in donkey IVM medium.
Trends of global and regional aetiologies, risk factors and mortality of lower respiratory infections from 1990 to 2019: An analysis for the Global Burden of Disease Study 2019
Authors: Kang Liangyu , Jing Wenzhan , Liu Jue , Liu Min 
Published: October 2022

AbstractBackground and ObjectiveLower respiratory infections (LRIs) are a leading cause of death worldwide. We aimed to estimate the trends of global and regional aetiologies, risk factors and mortality of LRIs from 1990 to 2019.MethodsFrom the Global Burden of Disease (GBD) Study 2019, we collected relevant data, including annual LRI deaths, mortality and deaths and mortality attributable to the four high‐burden aetiologies and 14 risk factors during 1990–2019. To quantify the temporal trends, estimated annual percentage changes (EAPCs) were calculated by fitting linear regression model.ResultsGlobally, the age‐standardized mortality due to LRIs decreased by an average of 2.39% (95% CI 2.33%–2.45%) per year, from 66.67 deaths per 100,000 in 1990 to 35.72 deaths per 100,000 in 2019. Low Socio‐demographic Index regions, South Asia and Sub‐Saharan Africa had the heaviest burden of LRIs. The age‐standardized mortality decreased in 18 GBD regions, whereas increased in Southern Latin America (EAPC = 1.20, 95% CI 1.03–1.37). LRIs led to considerable deaths among children under 5 years and adults older than 70 years. Streptococcus pneumoniae was the first leading aetiology, accounting for over 50% of LRI deaths. Household air pollution from solid fuels, child wasting and ambient particulate matter pollution were the three leading risk factors for LRI mortality in 2019.ConclusionLRIs remain an important health problem globally, especially in some vulnerable areas and among children under 5 and adults over 70 years. Future researches focusing on the aetiologies and risk factors for LRIs are needed to provide targeted and updated prevention strategies.
Resurgent back‐to‐the‐land and the cultivation of a renewed countryside
Authors: Sandström Emil 
Published: October 2022

AbstractIn connection to concerns about, for example, climate change, peak oil, pandemics and the depopulation of many rural areas, there has been a counter‐migration from urban to rural areas in past decades. An important part of this counter‐migration is the so‐called 'back‐to‐the‐land' migration of former urban residents who move to rural areas and adopt primarily agrarian lifestyles. Through a review of 48 migration letters in which migrants write about their experiences of moving from urban to rural areas to commence agriculture, this article explores the underlying ideals and agricultural practices of the back‐to‐land phenomena and discusses what significance this form of agricultural migration may have for understanding broader sustainability transformations and contemporary rural change. Important questions concern: What kinds of motives, practices and ideals underpin back‐to‐the‐land migration? What relevance does “back‐to‐the‐land” have for how we comprehend rurality and how the current food landscape is changing? Based on the letter reviews, this article illuminates four interconnected themes with regard to back‐to‐the‐landers practices and ideals. Back‐to‐the‐land as (i) rebelling against payroll work and meaningless lives in the cities, (ii) reinvention and retrotopia, (iii) reconnecting with nature and cultivating resilient alternatives and (iv) resistance and silent revolution. The article argues that the current back‐to‐land migration contributes to the construction of a renewed rurality—a reinvented form of rurality—that are adapted to suit both present and future needs in a world that is perceived as becoming more unruly. The article further suggests that, although back‐to‐the‐land migration may not yet have any significant material implications on the current food system, the ideals and practices the back‐to‐the‐landers profess, provide an important imaginary of how we can comprehend an alternative ‘rurality’ that reconnect people, land and food in more sustainable ways, through, for example, benign ways of practising agriculture and organising the food system. In this light, the current back‐to‐the‐land phenomena can be seen as a particular form of sustainability migration of voluntary peasantry that is based on retrotopian ideals of a rural past that is paired with progressive sustainability practices of the present.
End‐user‐oriented pedotransfer functions to estimate soil bulk density and available water capacity at horizon and profile scales
Authors: Richard Cécile , Lemercier Blandine , Michot Didier , Pichelin Pascal , Rémy Amandine , Berthier Lionel , Walter Christian 
Published: October 2022

AbstractSoil available water capacity (AWC) and bulk density (BD) are key properties for understanding water flows in soils, land‐use planning and irrigation management. As measuring these properties is costly and time‐consuming, pedotransfer functions (PTFs) are commonly used to predict BD and soil moisture at a specific matric potential and then estimate AWC. Currently, operational tools to estimate AWC at the soil profile scale from data easily available are lacking. In this study, new PTFs based on the regression‐tree method Cubist were developed at a regional scale to predict soil water contents at −10 kPa (field capacity) and −1585 kPa (permanent wilting point), and BD. A first PTF (PC model) required commonly measured soil properties (sand, silt, clay, organic carbon contents), while the second (PM model) required four additional predictors: qualitative information deriving from description of the soil profile. The models were validated with an independent dataset. Both models outperformed existing PTFs. AWC was then estimated at the horizon scale, soil‐profile scale and in the upper 30 cm of soil. The PM model performed better than the PC model with the training dataset at the profile scale (Nash‐Sutcliffe efficiency = 0.87 and 0.60; RMSE = 0.186 and 0.326 mm cm−1, respectively). Independent validation of AWC estimates at the profile scale by the PM and PC models yielded RMSE of 0.192–0.204 and 0.229–0.244 mm cm−1, respectively. The sensitivity of AWC to estimates of soil depth and coarse‐fragment content was tested. Results confirmed the importance of these variables resulting in soil observation to estimate AWC accurately.
Intangible trade: Understanding the relationship between trade barriers and mode of supply in services sectors
Authors: Khachaturian Tamar , Oliver Sarah 
Published: October 2022

AbstractIn recent years, increased availability of services trade data and measures of non‐tariff barriers has enabled more detailed analysis of trade patterns, including the relationship between different modes of service delivery across international borders. This paper uses a detailed, sector‐level structural gravity model to shed light on the question of whether services trade via foreign affiliate sales (also known as mode 3 trade) is a complement or substitute for cross‐border services trade (modes 1, 2, and 4) in 13 services sectors. In 9 of the 13 sectors considered, there is a negative and significant relationship between trade policies that limit foreign affiliate sales and cross‐border trade, indicating a complementary relationship between the two types of trade flows. This suggests that when services firms export, they rely on multiple modes of supply to deliver their products, considering factors such as the degree of service tradability over the internet, levels of customer interaction, and complexity of particular tasks.
Biology, distribution and management of the globally invasive weed Solanum elaeagnifolium Cav (silverleaf nightshade): A global review of current and future management challenges
Authors: Roberts Jason , Florentine Singarayer 
Published: October 2022

AbstractSolanum elaeagnifolium Cav (silverleaf nightshade) is a deep‐rooted, multi‐stemmed, perennial, herbaceous woody plant that has been observed to threaten agricultural and native biodiversity worldwide. It is widely agreed that without efficient integrated management, S. elaeagnifolium will continue to cause significant economic and environmental damage across multiple scales. It is estimated that the annual economic impact of S. elaeagnifolium in Australia exceeds AUD $62 million, with this figure likely to be much higher in other countries invaded by this plant. It can also tolerate a high level of abiotic stress and survive in a range of temperatures (below freezing point to 34°C) and areas with an average yearly rainfall between 250 and 600 mm. Its extensive deep taproot system is capable of regenerating asexually and with its many seed dispersal mechanisms; it can quickly spread and establish itself within a region. This makes containment and management of the species especially challenging. Previous management has largely been focused on biological control, competition, essential oils, grazing pressure, herbicide application and manual removal. Despite the large range of available management techniques, there has been little success in the long‐term control of S. elaeagnifolium, and only a handful of methods such as essential oils and herbicide application have shown reasonable success for controlling this weed. Therefore, this review aims to synthesise the identified and potentially useful approaches to control S. elaeagnifolium that have been recorded in the literature which deal with its biology, distribution and management. It also explores previous and current management techniques to ascertain the research gaps and knowledge required to assist in the effective and economically sustainable management of this invasive weed.
Roles and practices of specialist lung cancer nurses: a scoping review protocol
Authors: Brunelli Vanessa N. , Ramis Mary-Anne , Kynoch Kathryn 
Published: October 2022

ABSTRACT

Objective:
The objective of this scoping review is to map the available literature on the specialist lung cancer nurse role.

Introduction:
The international literature acknowledges the importance of specialist cancer nurses who provide supportive care to patients. Historically, however, there has been a lack of consistent evidence to inform development and implementation of the role.

Inclusion criteria:
This review will consider quantitative and qualitative studies of any design or methodology that report on role characteristics or behaviors, practices or activities, or other aspects of the specialist lung cancer nurse role in the acute care setting. Systematic reviews, professional body reports, as well as unpublished or published studies and reports will also be considered for inclusion. Textual or opinion papers will be excluded.

Methods:
This review will follow JBI methodology for scoping reviews. Relevant papers from 2006 to 2022, in any language, will be searched for in the following databases and registries: MEDLINE (PubMed), CINAHL (EBSCO), Web of Science, Embase, and the Cochrane Register of Controlled Trials. Websites to be searched will include the World Health Organization, International Council of Nurses, and Agency for Healthcare Research and Quality. ProQuest Dissertations and Theses (ProQuest) and Grey Matters (CADTH) will be searched for unpublished literature. Results will be presented in tabular and narrative format and mapped according to the specified concepts of interest, as well as to the domains of practice for specialist nursing roles.
Characteristics of natural environment use by occupational therapists working in mental health: a scoping review protocol
Authors: Bishop Ruth , Underwood Frazer , Burrows Lisa , Fraser Fiona , Shawe Jill 
Published: October 2022

ABSTRACT

Objective:
The objective of this review is to identify and characterize the use of the natural environment/outdoor space by occupational therapists working in mental health care.

Introduction:
Research has shown that the natural environment is beneficial for our health and can be used to benefit people who are experiencing mental health problems. Occupational therapists are well placed to assess and utilize the environment when treating people with mental health problems, but the use of the natural environment/outdoor space by occupational therapists working in mental health is unclear.

Inclusion criteria:
The scoping review will include both primary research and gray literature relating to the use of the natural environment/outdoor space in mental health occupational therapy practice. The review will be limited to studies published in English. There will be no geographical or age restrictions.

Methods:
Embase (Ovid), MEDLINE (Ovid), CINAHL (EBSCO), PsycINFO (ProQuest), AMED (EBSCO), Trip Database, EMCARE (Ovid), and OTSeeker will be search for studies. Unpublished studies and gray literature will be searched using GreyNet and National Grey Literature Collection, alongside professional magazines and websites. Titles and abstracts will be screened by 2 independent reviewers for assessment against the inclusion criteria, followed by a full-text review and data extraction. Any disagreements will be discussed with a third reviewer. Data will be extracted using a data extraction tool developed by the reviewers and presented in a tabular format, accompanied by a narrative summary describing how the results relate to the review objective and question.