bluuebunny/crossref_metadata_2025_split huggingface dataset:
Museum education for pre‐service teachers in an online environment: Challenges and potentials
Authors: Pavlou Victoria 
Published: May 2022

AbstractIt was widely expected that the academic year 2020‐2021 would be a different experience for all involved in educational processes. Everybody had to readjust and reimagine their practice in order to respond to the new reality of teaching university courses online due to the COVID‐19 pandemic. This article focuses on the challenges and opportunities that were created because of the pandemic for experiential and collaborative learning during a museum education course addressed to student teachers in the context of initial teacher training. It focuses on a series of activities and reflective practices that took place in order to promote student engagement and active learning in the online environment within which the course was materialized, such as object‐based learning and museum visits. It discusses opportunities for an embodied living inquiry as a space for learning and researching. These experiences have implications for museum education through online training and contributes to the digital transformation of teacher training courses in Higher Educational Institutions.
Genotype by feeding regimen interactions for slaughter traits in rabbit and expected responses under restricted and full feeding
Authors: Sánchez Juan Pablo , Ragab Mohamed , Mínguez Carlos , Piles Miriam 
Published: May 2022

AbstractThe interaction between the genotype and feeding regimen (G×FR) for slaughter traits was estimated from data corresponding to 2557 animals under full (FF) and 2424 with restricted feeding (RF). Expected responses to selection under different scenario regarding feeding regimen were also calculated. Body weight at slaughter (SW), carcass weight (CW) and dressing out percentage (DoP) were analysed by using linear animal models in which records obtained under different feeding regimes were treated as different traits. Animals belonged to Caldes line, selected for average daily gain (G) under ad libitum feeding. The selection process information was included in the analyses. Marginal posterior mean of heritabilities were 0.102 for G, and 0.364, 0.257 and 0.167 for SW, CW and DoP under FF feeding. The corresponding values for animals fed on RF were 0.243, 0.203 and 0.379 for SW, CW and DoP, respectively. Genetic correlations between G and CW were positive and moderate, and those between G and DoP were low. The estimated genetic correlation between SW, CW and DoP under different feeding regimens were: 0.73, 0.69 and 0.87, respectively. These correlations cannot be said to be far enough from one to generate relevant G×FR interaction variance, which were estimated to be only 11.1%, 8.6% and 5.3% of the mean of the phenotypic variance for SW, CW and DoP, respectively. This lack of G×FR interaction variance, jointly with the higher heritability of DoP under RF, explains that the genetic improvement of DoP can be done more efficiently recording traits on animals under RF, even if the interest is on the performances under FF, i.e. by indirect selection.
Dielectric‐based tissue thickness measured during radiofrequency catheter ablation
Authors: Schillaci Vincenzo , Stabile Giuseppe , Arestia Alberto , Shopova Gergana , Agresta Alessia , Salito Armando , Giannitti Carlo M. , Natalizia Andrea , De Simone Antonio , Solimene Francesco 
Published: May 2022

AbstractIntroduction: A new dielectric‐based method (KODEX‐EPD mapping system, EPD Solutions, a Philips company) for measuring tissue thickness at the catheter‐tissue interface has recently been developed. We reported preliminarydata on real‐time catheter‐based measuring myocardial wall thickness in vivo, during typical atrial flutter radio frequency ablation.Methods and Results: The study population consisted of 12 consecutive patients, suffering from symptomatic paroxysmal or persistent cavo‐tricuspid isthmus dependent, counter clockwise and clockwise AFL, under going a first catheter ablation between April 2021 and November 2021. The new KODEX‐EPD function, Wall Viever, was used to calculate atrialwall thickness. The atrial wall thickness was significantly higher closeto the tricuspid annulus than close to the inferior vena cava (3.6 ± 0.5 mm vs 2.4 ± 0.3 mm, p < .001) and a trend towards a progressive decrease of atrial wall thickness was observed moving the mapping catheter from the tricuspidvalve to the inferior vena cava.Conclusions: Thenew KODEX‐EPD function, Wall Viever, allowed us to assess atrial wall thickness during atrial flutter radio frequency ablation.
Reusable device for cooling beverages and liquid foods: A novel approach to replace ice in glass
Authors: Kumar Guruvanna Mahesh , Mutharayappa Manjunatha , Rajappa Divyashree Hulluru , Anand Bangalore Aswathnarayana 
Published: May 2022

AbstractVogue of drinking beverages and liquid foods (BLFs) with ice is embedded and ever increasing in our hasty busy life. Direct use of unsafe ice and/or food ice containing pathogens in BLFs is threat to human health. In the current study, as an alternate to ice, a reusable cooling device was developed to cool some widely consumed BLFs. The device engineered with phase change materials (PCM), namely, portable water (PW), distilled water (DW), and PW + DW and the effect of solutes (salt and sugar @2%, 4%, and 6%) in PW and DW was demonstrated for its ability to store total cool energy before evaluating its cooling performance in BLFs. The PCMs, namely, DW and DW + 2% salt taken 195 and 240 min, respectively to reach target −19°C storing highest cool energy than other PCMs evaluated. Cooling of BLFs by the device containing different PCMs was significantly different with cooling time and PCM type while highest cooling performance was exhibited by DW followed by DW + 2% salt. It was found that 6.6–17.0°C and 17.7–23.3°C drop in temperature (ΔT) range within 5 and 30 min of cooling process, respectively using the device with DW inside. The ΔT (maximum temperature drop) was in the order for potable water > beer > soft drink > whisky > butter milk/flavored milk > orange juice > apple juice > lassi during cooling using the device. The developed PCM‐based device could be used as an alternate to ice for cooling 200 mL of beer, whisky, soft drink, orange juice, apple juice, butter milk, flavored milk, and lassi in drinking glass.Practical applicationsThe reusable device is engineered with phase change material (PCM) inside safely. It would replace ice for cooling by reducing 23°C in a drinking glass of beverages and liquid foods (BLFs) because of its simple in design, compact and safe. It can be sterilized and washed easily and quickly because of its hygienically engineered mirror finish surface. It can be used for years in hotels, retails and catering premises, road side shops, local open markets, eateries retail shops, pubs and bars because of its durable material of construction. It can easily be recharged in refrigerators and even using ice. The data and research findings on sensible cooling, phase change, and cooling capacity of PCM generated with the device would be very useful for Food Process Engineering field for applications, namely, heat transfer, refrigeration, air conditioning, and cold chain management and for translating research work in the field.
Rapid responses: Receptor‐like kinases directly regulate the functions of membrane transport proteins in plants
Authors: Li Xiaopeng , Zhang Jingjie , Shi Hongyong , Li Bo , Li Jia 
Published: May 2022

ABSTRACTReceptor‐like kinases (RLKs) are a large group of plant‐specific transmembrane proteins mainly acting as receptors or co‐receptors of various extracellular signals. They usually turn extracellular signals into intracellular responses via altering gene expression profiles. However, recent studies confirmed that many RLKs can physically interact with diverse membrane‐localized transport proteins and regulate their activities for speedy responses in limited tissues or cells. In this minireview, we highlight recent discoveries regarding how RLKs can work with membrane transport proteins collaboratively and thereby trigger cellular responses in a precise and rapid manner. It is anticipated that such regulation broadly presents in plants and more examples will be gradually revealed when in‐depth analyses are conducted for the functions of RLKs.
bZIP71 delays flowering by suppressing Ehd1 expression in rice
Authors: Li Xiufeng , Tian Xiaojie , He Mingliang , Liu Xinxin , Li Zhiyong , Tang Jiaqi , Mei Enyang , Xu Min , Liu Yingxiang , Wang Zhenyu , Guan Qingjie , Meng Wei , Fang Jun , Zhang Jian , Bu Qingyun 
Published: May 2022

ABSTRACTFlowering time is a fundamental factor determining the global distribution and final yield of rice (Oryza sativa). Although diverse flowering time genes have been reported in this crop, the transcriptional regulation of its key flowering genes are poorly understood. Here, we report that a basic leucine zipper transcription factor, bZIP71, functions as a flowering repressor. The overexpression of bZIP71 delays flowering, while the bzip71 mutant flowers early in both long‐day and short‐day conditions. A genetic analysis showed that the regulation of flowering by bZIP71 might be independent of Heading date 2 (Hd2), Hd4, and Hd5. Importantly, bZIP71 directly associates with the Early heading date 1 (Ehd1) promoter and represses its transcription, and genetically the function of bZIP71 is impaired in the ehd1 mutant. Moreover, bZIP71 interacts with major components of polycomb repressive complex 2 (PRC2), SET domain group protein 711 (SDG711), and Fertilization independent endosperm 2 (FIE2), through which bZIP71 regulates the H3K27me3 level of Ehd1. Taken together, we present a transcriptional regulatory mechanism in which bZIP71 enhances the H3K27me3 level of Ehd1 and transcriptionally represses its expression, which not only offers a novel insight into a flowering pathway, but also provides a valuable putative target for the genetic engineering and breeding of elite rice cultivars.
Immunohistochemical expression of Axin‐2, as an implication of the role of stem cell in scar pathogenesis and prognosis
Authors: Bazid Heba A. S. , Samaka Rehab Monir , Mousa Marwa E. A. , Seleit Iman 
Published: May 2022

AbstractBackgroundWound healing is a multi‐phased process. A disruption in these phases could result in a persistent wound or an atypical scar. Wounding activates wingless proteins (Wnt) signaling, which aids in the healing process. Axis inhibition protein‐2 regulates a variety of cellular activities through the Wnt and other pathways.AimTo assess the role of Axin‐2 in patients with abnormal scars, using immunohistochemical study.MethodsThis case–control study enrolled a total of 60 participants: 30 patients with abnormal scars (12 hypertrophic scars, 13 atrophic scars, and 5 keloid scars) and 30 age, sex, and site matched, apparently healthy controls. For immunohistochemistry examination of Axin‐2 expression, skin samples were obtained from (i) lesional and (ii) perilesional skin of patients with aberrant scars, as well as (iii) normal control's skin.ResultsEpidermal Axin‐2 expression positivity, cellular topography, intensity, and H score showed significant differences between the groups (p < 0.05). In the dermis (fibroblast/myofibroblast), there were significant differences in Axin‐2 expression positivity, location, intensity, and H score (p < 0.001 for all). The epidermal Axin‐2 H score and the Manchester scale had a significant positive correlation (r = 0.832, p = 0.001). The epidermal Axin‐2 H score and age (r = −0.576, p = 0.001), and the Stony Brook scale (r = −0.419, p = 0.021), had significant negative correlations.ConclusionAxin‐2 overexpression might be accused in pathogenesis of abnormal scar and clinical worse scar outcome. In order to deprive scars of their regenerative cell pools, future scar therapies may target Axin‐2 as a stem cell marker.
The effectiveness of social media intervention in people with diabetes: An integrative review
Authors: Yaagoob Esmaeel , Hunter Sharyn , Chan Sally 
Published: May 2022

AbstractAimThis integrative review aimed to synthesise the available quantitative and qualitative studies on the effectiveness of diabetes self‐management education (DSME) delivered through social media on glycaemic control (HbA1c), knowledge, health‐related quality‐of‐life (HRQoL), anxiety, depression and self‐efficacy in people with diabetes mellitus.BackgroundDSME is the main component of diabetes management which contributes to behavioural changes and the improvement of metabolic control and self‐monitoring skills. Due to limited face‐to‐face access to healthcare services, social media has increasingly been used to deliver DSME for people with diabetes. However, there is a paucity of reviews addressing the effectiveness of using social media in delivering DSME.DesignAn integrative review was conducted based on Whittemore and Knafl's (2005) methodology.MethodsThe following databases were searched for relevant studies published between 2000 and 2020: Cumulative Index to Nursing and Allied Health Literature (CINAHL), MEDLINE, Cochrane Library, PsycINFO, EMBASE, EMCare and Google Scholar. The quality of the included studies was assessed using the Mixed Methods Appraisal Tool. The PRISMA checklist for systematic reviews was used.ResultsA total of 13 studies met the inclusion criteria and were included in this review. Facebook and WhatsApp were the most common social media platforms used to deliver DSME intervention. Nurses were the most frequent DSME providers. The duration and content of DSME in the reviewed studies varied. Consistent positive outcomes were found on glycaemic control, diabetic knowledge and self‐efficacy. No studies considered the effect of DSME on HRQoL, anxiety and depression.ConclusionsSocial media DSME can be effective in reducing HbA1c levels, increasing diabetic knowledge and self‐efficacy. Further studies are needed to examine the effectiveness of using social media to deliver DSME intervention on HRQoL, anxiety and depression.Relevance to clinical practiceThis review provides nurses and healthcare professionals with evidence to support the use of social media to deliver DSME for people with diabetes. DSME delivered via social media supported by nurses would overcome limitations of face‐to‐face delivery such as geographical distance, travelling time, or other limited resources by patients with diabetes.
Testing Disagreement Models
Authors: CHANG YEN‐CHENG , HSIAO PEI‐JIE , LJUNGQVIST ALEXANDER , TSENG KEVIN 
Published: May 2022

ABSTRACTWe provide plausibly identified evidence for the role of investor disagreement in asset pricing. Our natural experiment exploits the staggered implementation of the Electronic Data Gathering, Analysis, and Retrieval (EDGAR) system, which induces a reduction in investor disagreement. Consistent with models of investor disagreement, EDGAR inclusion helps resolve disagreement around information events, leading to stock price corrections. The reduction in disagreement following EDGAR inclusion also reduces stock price crash risk, especially among stocks with binding short‐sale constraints and high investor optimism.
Biomechanical Analysis of Different Framework Design, Framework Material and Bone Density in the Edentulous Mandible With Fixed Implant‐Supported Prostheses: A Three‐Dimensional Finite Element Study
Authors: Yu Wenqian , Chen Siyi , Ma Li , Ma Xiaoni , Xu Xin 
Published: May 2022

AbstractPurposeThe objective of this finite element study was to investigate the effect of different framework designs, framework materials, and bone densities on the stress distribution of fixed implant‐supported prostheses for edentulous mandibles.Materials and methodsUnder the condition of 2‐mm cortical bone, 16 models were created in the edentulous mandible to simulate different framework designs (1‐piece or 3‐piece frameworks) with different framework material (pure titanium, zirconia, polyetheretherketone, or carbon fiber‐reinforced polyetheretherketone) in‐high or low‐density trabecular bone. Then, vertical loading and oblique loading at 75° were applied to the anterior and posterior regions. The stress distribution and stress concentration region of implant and peri‐implant bone with different combinations were compared by finite element analysis.ResultsThe use of the 1‐piece zirconia framework in high‐density trabecular bone improved stress distribution on implants and peri‐implant bone. The region of stress concentration is located in the buccal cervix of the distal implants and the distobuccal portion of the cortical bone in all models. To improve the stress distribution on fixed implant‐supported dentures for edentulous mandibles, the 1‐piece framework and zirconia represent the better combination.ConclusionUnder the condition of 2‐mm cortical bone thickness, the full‐arch zirconia framework had minimum von Mises stress on implants and peri‐implant bone in all models, and high trabecular bone density greatly decreased the stress on cortical bone.
Size and shape in the evolution of the worker head in Pheidole ants (Hymenoptera: Formicidae)
Authors: Casadei‐Ferreira A. , Feitosa R. M. , Pie M. R. 
Published: May 2022

AbstractThe division of labor into sterile and reproductive castes in social insects is often reflected in marked morphological differences, which might have played an important role in the remarkable adaptive success of these organisms. Some ant lineages have undergone further morphological differentiation, with the evolution of differences within the worker caste. In this study, we characterize morphological diversity in the head of Pheidole ants by comparing differences in size and shape among species and between minor and major worker subcastes. To this end, we integrate data from high‐resolution images, geometric morphometrics, and phylogenetic comparative methods. Our results indicated differences in morphological variation of each subcaste with respect to their geographical distribution, with distinct morphological patterns and evolutionary routes related to head shape. Allometry was shown to be a crucial element for the differentiation within and between each subcaste, corroborating the role of size in their morphological evolution. Additionally, we observed that closely related species often diverge considerably in morphospace, whereas convergence in their morphospace occupation characterizes some West and East Hemisphere species. Finally, although multiple shifts in the rate of morphological evolution occurred during the Miocene, the timing and position of these shifts were independent of size and shape, suggesting that their evolution has been decoupled throughout Pheidole evolution.
Physicochemical quality of reservoir sediment in irrigation dams of Northern Ghana
Authors: Abagale Felix K. , Adongo Thomas Apusiga 
Published: May 2022

AbstractThe present study assessed the physicochemical quality of irrigation dam reservoir sediment deposits for possible use in enriching soils in Northern Ghana. The surface area of the 9 study reservoirs was divided into upstream, midstream and downstream sections, with 18 undisturbed sediment samples taken at 0–30 cm depth for determining the soil dry bulk density, and 30 samples collected for analysis of particle size distribution, pH, macronutrients, CEC, EC, ESP and SAR. Reservoir sediments were rich in plant macronutrients (K, Ca and Mg) and organic matter and high in silt and clay content. The dry bulk density ranged from 1.10 ± 0.02 g/cm3to 1.39 ± 0.08 g/cm3, while the sediment particle sizes were 10.3%–24.8% sand, 43.7%–53.1% silt and 30.6%–37.8% clay. The sediment pH ranged from a moderately acidic level of 5.48–6.64, with high levels of organic carbon (1.37%–2.96%) and organic matter (2.36%–5.10%). The total nitrogen (N) was found to be low (0.14%–0.29%), while the phosphorus (P) ranged from 2.6% to 4.9%, about 10 times higher than the FAO recommended normal average range. Except for the potassium (K) in two of the present study reservoirs, the exchangeable bases concentrations in the sediments were within acceptable levels for crop production. The CEC values were within moderate levels (13.69 to 29.84 cmol/kg), corresponding to a non‐expanding, chemically inactive clay, while the salinity and sodicity were absent, with the EC varying between 0.03 and 0.27 dS/m and ESP ranging from 1.8% to 12.9%. Pearson's correlation analyses indicated both positive and negative relationships among the various physicochemical parameters. Based on the present study results, desilted irrigation reservoir sediments, being rich in all plant nutrients, except for N, appear to have great potential to enhance crop production for farmers.
Multi‐omics analysis identifies a CYP9K1 haplotype conferring pyrethroid resistance in the malaria vector Anopheles funestus in East Africa
Authors: Hearn Jack , Djoko Tagne Carlos S. , Ibrahim Sulaiman S. , Tene‐Fossog Billy , Mugenzi Leon M. J. , Irving Helen , Riveron Jacob M. , Weedall Gareth D. , Wondji Charles S. 
Published: May 2022

AbstractMetabolic resistance to pyrethroids is a menace to the continued effectiveness of malaria vector controls. Its molecular basis is complex and varies geographically across Africa. Here, we used a multi‐omics approach, followed‐up with functional validation to show that a directionally selected haplotype of a cytochrome P450, CYP9K1 is a major driver of resistance in Anopheles funestus. A PoolSeq GWAS using mosquitoes alive and dead after permethrin exposure, from Malawi and Cameroon, detected candidate genomic regions, but lacked consistency across replicates. Targeted sequencing of candidate resistance genes detected several SNPs associated with known pyrethroid resistance QTLs. The most significant SNPs were in the cytochrome P450 CYP304B1 (Cameroon), CYP315A1 (Uganda) and the ABC transporter gene ABCG4 (Malawi). However, when comparing field resistant mosquitoes to laboratory susceptible, the pyrethroid resistance locus rp1 and SNPs around the ABC transporter ABCG4 were consistently significant, except for Uganda where SNPs in the P450 CYP9K1 was markedly significant. In vitro heterologous metabolism assays with recombinant CYP9K1 revealed that it metabolises type II pyrethroid (deltamethrin; 64% depletion) but not type I (permethrin; 0%), while moderately metabolising DDT (17%). CYP9K1 exhibited reduced genetic diversity in Uganda underlying an extensive selective sweep. Furthermore, a glycine to alanine (G454A) amino acid change in CYP9K1 was fixed in Ugandan mosquitoes but not in other An. funestus populations. This study sheds further light on the evolution of metabolic resistance in a major malaria vector by implicating more genes and variants that can be used to design field‐applicable markers to better track resistance Africa‐wide.