bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stacked 1/3 Tubular Plates for Fixation of Pediatric Forearm Fractures: A Biomechanical Study
Authors: Hearon Bernard , Cooper Benjamin , Wendling Alexander , Isaacs-Pullins Sharon , White Joel , Hollenbeck Steven 
Published: February 2022

Introduction. Among operatively treated pediatric forearm fractures, many different fixation constructs are described. The goal of this study is to define the biomechanical properties of a double stacked 1/3 tubular plate construct used by the senior author for some fractures and to review available literature regarding the use of stacked plates.
Methods. Biomechanical testing was performed by 4-point bending of 3 different plate constructs: 1/3 tubular plate, stacked 1/3 tubular plates, and 2.7 mm LC-DCP plate. Five test specimens were evaluated for each of the three plate constructs. From stress-strain curves, flexural stiffness (N/mm), force to cause plastic deformation (N), and force to cause 10º bend (N) were calculated and compared using standard t-test statistics.
Results. Key outcome parameter means (± SD) for the three plate constructs (1/3 tubular plate, stacked 1/3 tubular plates, and 2.7 mm LC-DCP plate) are reported respectively as follows: flexural stiffness (55.4 ± 3.5 N/mm, 131.7 ± 3.5 N/mm, 113.3 ± 12.1 N/mm), force to cause plastic deformation (113.6 ± 11.0 N, 242.1 ± 13.0 N, 192.2 ± 17.9 N), and force to cause a 10º bend (140.0 ± 8.4 N, 299.4 ± 14.1 N, 265.5 ± 21.2 N). Mean values of all three measures were significantly larger for the stacked 1/3 tubular plates than for the other plate constructs.
Conclusions. The stacked 1/3 tubular plate construct was biomechanically superior to the other plate constructs. Stacked plating significantly improves stiffness of the fracture fixation construct supporting use of this technique in selected trauma cases.
Zararlı yazılım kaynaklı veri kaçırma ataklarına karşı yeni bir doküman sınıflandırma algoritması
Authors: KESENEK Yahya , ÖZÇELİK İbrahim , KAYA Emrah 
Published: February 2022

Günümüzde
değerli verilerin saklanması ve sadece yetkili şahıs veya kurumlarca
kullanılması önem arz etmektedir. Genel olarak verinin korunmasına yönelik
geliştirilen veri sızıntısı önleme (Data Leakage Prevention-DLP) çözümleri
zararlı yazılım kaynaklı saldırıları göz ardı etmekte, parmak izi (fingerprinting) eşleştirme ve kurallı ifadeler (regular
expression) benzeri yöntemler kullanan algoritmalar yer almaktadır. Oysaki
doküman içeriğine yönelik yapılan saldırılar neticesinde bu algoritmalar
atlatılabilmektedir.

Zararlı
yazılım kaynaklı veri sızıntısına karşı dayanıklı bir algoritmanın sunulduğu bu
çalışmada, zararlı yazılımların saldırı türüne bağlı kalmayan bir çözüm
önerilmektedir. Çalışma kapsamında, yer değiştirme, yapısal cümle saldırıları,
modifikasyon saldırıları, karartma saldırıları ele alınmıştır. Bu saldırılara
karşı yazım düzeltimi, kelime-gram ve karakter-gram, k-skip-n-gram ve LSA
kullanılarak, saldırı altında daha iyi bir sınıflama yapılması için özellikler
çıkarımı sağlanmıştır.

Çıkarılan
özellikler, Karar Destek Makineleri, Rasgele Orman ve Çok Katmanlı Algılayıcı
kullanarak Oylamalı Sınıflandırıcı ile en çok oy alan yönteme göre sınıflama
tahmini yapılmıştır.

Ayrıca
modifikasyon saldırılarında faydalı olan Yazım Düzeltme yönteminin etkisi
farklı aşamalarda uygulanarak gösterilmiştir.
EVALUASI PELAKSANAAN MODEL PEMBELAJARAN TEACHING FACTORY DI SMKN 1 CIBADAK
Authors: Prasloranti Zahra Pitaloka , Bukit Masriam , Maharani Shinta 
Published: February 2022

Model pembelajaran teaching factory(TEFA) adalah model pembelajaran di SMK berbasis produksi atau jasa yang mengacu pada standar, prosedur, dan suasana seperti di industri. Salah satu sekolah yang mengadopsi model pembelajaran TEFA adalah SMK Negeri 1 Cibadak. Dalam keberlangsungan suatu program, perlu ada proses yang digunakan untuk menilai tingkat keterlaksanaan program yang disebut evaluasi. Penelitian ini menggunakan model evaluasi CIPP yang berorientasi kepada empat komponen yaitu context, input, process, dan product. Tujuan penelitian ini adalah untuk mengetahui sejauh mana implementasi model pembelajaran TEFA ditinjau dengan komponen CIPP. Pengumpulan data dalam penelitian ini dilakukan melalui kuesioner, wawancara, observasi, dan dokumentasi. Hasil penelitian diketahui bahwa pelaksanaan model pembelajaran TEFA komponen contexttermasuk kedalam kategori sangat sesuai terhadap relevansi pelaksanaan dengan tujuan program, visi, dan misi sekolah. Komponen inputtermasuk kedalam kategori sesuai dengan manajemen sekolah, sarana-prasarana, dan sumber daya manusia. Komponen processtermasuk kedalam kategori sangat sesuai dengan pola pembelajaran dan marketing. Komponen product termasuk kedalam kategori sangat sesuai dengan produk dan kompetensi siswa. Seluruh komponen CIPP model pembelajaran TEFA telah terlaksana dengan baik tetapi memerlukan peningkatan dalam pengembangan teknologi, penyelarasan kurikulum, pengelolaan sumber daya, dan pemasaran produk.
Distribución espacial de materiales arqueológicos en el hisn del Cerro del Castillo (Capilla, Badajoz)
Authors: Sanabria Murillo Diego 
Published: February 2022

En este estudio se aborda de forma preliminar el reparto de los materiales arqueológicos hallados en la excavación de una zona de la ocupación andalusí situada extramuros del hisn del Cerro del Castillo (Capilla, Badajoz). A través de este trabajo se analiza la representación de los distintos tipos de objetos en relación con los contextos espaciales en los que fueron recuperados, así como los perfiles funcionales que arrojan sus análisis tecnotipológicos y morfológicos.
Solving USE problems in computer science using the Python language
Authors: Ильченко О.Ю. , Сырицына В.Н. , Кадеева О.Е. 
Published: February 2022

Рассматриваются предметные и методические аспекты единого государственного экзамена по информатике. Анализируются особенности решения сложной части заданий единого государственного экзамена по программированию на языке Python, приводятся примеры решения таких заданий.
Subject and methodological aspects of the unifi ed state examination in informatics are considered. The peculiarities of solving a complex part of the exam tasks in Python programming are analyzed, examples of solving such tasks are given.
Investment, Deposit Interest Rates, and Real Sector Performance: A Case Study of Islamic Finance in Malaysia
Authors: Wilantari Regina Niken , Widarni Eny Lestari , Bawono Suryaning 
Published: February 2022

This study aims to examine the influence of interest rates, GDP, consumption, and investment on Islamic finance in Malaysia. Also, it focuses on the causal relationship between the macroeconomic and humanistic approach in understanding the role of Muslim economics. Data were analyzed using the Vector Error Correction Model and the results showed that interest rates negatively affect the real sector. Therefore, the Islamic financial system with a zero or no interest-based interest rate tends to promote a social economy
Nature and Aspects of Gender Integration During Election Violence in Kibera Slum, Kenya
Authors: M. Njeru Fridah , Kassilly Janet , Matanga Frank K. 
Published: February 2022

Election violence has the potential to threaten the peace and security of many nations and destabilize the social fabric. Scholars have argued that women and children bear the greatest burden in times of violence compared to men. The main purpose of this study was to assess the nature and aspects of gender integration during election violence in Kibera slum, Kenya. The study was guided by social integration theory by Emille Durkheim and employed the descriptive research design. Fischer formulae as suggested was used to arrive at the sample size of 384 respondents;
S = X2 NP (1-P) / d2 (N-1) + X2 P (1-P). Data were collected by use of interviewee assisted questionnaires and unstructured interview schedules. Data were analyzed by use of the statistical packages for social scientists (SPSS version 17). Data were presented in form of frequency tables, bar graphs, pie charts and verbatims, Measures of data analysis used included the chi square, mean, R spearman’s rank order correlation. The study established that Kibera residents had a moderately cordial relationship with each other during election violence. Majority could seek help or be helped, buy property or land, marry or be married and employ or be employed by someone outside their ethnic, social class political and religious affiliations. Election violence had a negative relationship with ethnic affiliations, social class, political affiliation and religious affiliation aspects of gender integration, that is, an increase in election violence would lead to a decrease in gender integration. Generally, women were more integrated compared to men. The study recommends that NGOs, CBOs and FBOs enhance their non-partisan advocacy and carry out civic education to enlighten Kibera residents and Kenyans at large on the importance of gender integration especially during the elections.
Socio-Political Resistance in Sindh: From Ancient times to British India
Authors: Chandio Abdul Shakoor , Chang Ali Qasim 
Published: February 2022

If there is a discussion about the resistance in Sindh it had played an important role in history. It helped Sindh on the two fronts. One of the fronts of resistance had helped Sindh to preserve and maintain the age-old separate and distinct Identity from the foreign aggressions. Sindhi people have boldly stood against foreign invaders. It is another matter that like any other nation, Sindhi people sometimes succeeded in this regard to defend their motherland, and sometimes, they failed. But it is clear evidence that Sindh has staunchly opposed the foreign plunderers and attackers. The second important level of resistance is within the society. Sindhi people have initiated individual and collective levels movements against prevailing exploitation and injustice in the society. Sufis have played their part in this regard to curtail religious extremism and to strive hard to bring religious tolerance, harmony, and peace loving society. Besides the Sufis movement, Sindhi scholars, students, women, peasants have long struggled for the major contradictions and injustice in society. Like every other society, now there are various political parties and organizations working in Sindh. A variety of leftist political parties and innumerable rightist political parties are doing their politics. There exists civil society, women’s organizations, and student organizations working for the downtrodden class of society. Nationalist politics with respect to the vested interests of Sindh is commonplace. This was the brief nature of resistance which had remained insignificant in shaping and preserving the separate and distinct identity of Sindh.
Aristotle’s "Nicomachean Ethics": Laying the Foundations for a Pragmatist Consideration of Human Knowing and Acting
Authors: Prus Robert 
Published: February 2022

Whereas a great many academics have presumed to speak knowledgeably about Aristotle's work, comparatively few have actually studied his texts in sustained detail and very few scholars in the social sciences have examined Aristotle's work mindfully of its relevance for the study of human knowing and acting on a more contemporary or enduring plane.
Further, although many people simply do not know Aristotle's works well, even those who are highly familiar with Aristotle's texts (including Nicomachean Ethics) generally have lacked conceptual frames for traversing the corridors of Western social thought in more sustained pragmatist terms. It is here, using symbolic interactionism (a sociological extension of pragmatist philosophy) as an enabling device for developing both transsituational and transhistorical comparisons, that it is possible to establish links of the more enduring and intellectually productive sort between the classical scholarship of the Greeks and the ever emergent contemporary scene.
After (1) overviewing the theoretical emphasis of symbolic interactionism, this paper (2) locates Aristotle's works within a broader historical context, (3) situates Aristotle's Nicomachean Ethics within the context of his own work and that of his teacher Plato, and (4) takes readers on an intellectual voyage through Aristotle's Nicomachean Ethics. Not only does his text address a great many aspects of human lived experience, but it also has great instructive value for the more enduring study of human group life. Accordingly, attention is given to matters such as (a) human agency, reflectivity, and culpability; (b) definitions of the situation; (c) character, habits, and situated activities; (d) emotionality and its relationship to activity; (e) morality, order, and deviance; (f) people's senses of self regulation and their considerations of the other; (g) rationality and judgment; (h) friendship and associated relationships; (i) human happiness; and (k) intellectual activity.
In concluding the paper, one line of inquiry that uses contemporary symbolic interaction as resource for engaging Aristotle's Nicomachean Ethics is suggested. However, as indicated in the broader statement presented here, so much more could be accomplished by employing symbolic interactionism as a contemporary pragmatist device for engaging Aristotle's Nicomachean Ethics.
Exploring Different Interaction Among Features For CTR Prediction
Authors: Yang Leilei , Zheng Wenguang , Xiao Yingyuan 
Published: February 2022

Abstract
Click-through rate (CTR) prediction occupies a very important position in recommendation systems and computational advertising. Accurate prediction of the click-through rate can help advertisers make more detailed advertising and marketing planning and can also help the media in defining their service audience and recommend more popular content to users more clearly. In this paper, we propose a model to make full use of the explicit feature interactions to improve the click-through rate of advertising. In the second-order feature interactions, our model not only considers the fact that the same feature uses different latent vectors when interacting with other features but also adds the latent vectors of each feature to form the embedding vector of the whole feature and then carries out explicit high-order interaction, to learn more nonlinear relations. We, inspired by the Squeeze-and-Excitation Networks (SENet), give different weights to different feature interactions. Extensive experimentation has been done on Avazu and Criteo to show that our model is better than the existing advanced models.
Identification of TARDBP Gly298Ser as a Founder Mutation for Amyotrophic Lateral Sclerosis in Southern China
Authors: Xu Fanxi , Huang Sen , Li Xu-Ying , Lin Jianing , Feng Xiuli , Xie Shu , Wang Zhanjun , Li Xian , Zhu Junge , Lai Hong , Xu Yanming , Huang Xusheng , Yao Xiaoli , Wang Chaodong 
Published: February 2022

Abstract
Background: Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by predominant impairment of upper and lower motor neurons. Over 50 TARDBP mutations have been reported in both familial (FALS) and sporadic ALS (SALS). Some mutations in TARDBP, e.g. A382T and G294V, have genetic founder effects in certain geographic regions. However, such prevalence and founder effect have not been reported in Chinese. Methods: Whole-exome sequencing (WES) was performed in 16 Chinese FALS patients, followed by Sanger sequencing for the TARDBP p.Gly298Ser mutation (G298S) in 798 SALS patients and 1,325 controls. Haplotype analysis using microsatellites flanking TARDBP was conducted in the G298S-carrying patients and noncarriers. The geographic distribution and phenotypic correlation of the TARDBP mutations reported worldwide were reviewed. Results: WES detected the TARDBP G298S mutation in 8 FALS patients, and Sanger sequencing found additional 8 SALS cases, but no controls, carrying this mutation. All the 16 cases came from Southern China, and 7 of these patients shared the 117-286-257-145-246-270 allele for the D1S2736-D1S1151-D1S2667-D1S489-D1S434-D1S2697 markers, which was not found in the 92 non-carrier patients (0/92) (p <0.0001). The A382T and G298S mutations were prevalent in Caucasians and Eastern Asians, respectively. Additionally, carriers for the M337V mutation are dominated by bulbar onset with a long survival, whereas those for G298S are dominated by limb onset with a short survival.Conclusions: Some prevalent TARDBP mutations are distributed in a geographic pattern and related to clinical profiles. TARDBP G298S mutation is a founder mutation in the Southern Chinese ALS population.
Engineering POLYTAC Nanoparticles for Bioorthogonal Click Reaction-Enforced Protein Degradation and Breast Cancer Therapy
Authors: Yu Haijun , gao jing , Zhu Qiwen , Hou Bo , Yang Lei , Jiang Xingyu , Zou Zhifeng , Li Xutong , Xu Zhiai , Xu Tianfeng , Zheng Mingyue , Xu Huixiong 
Published: February 2022

Abstract
PROteolysis TArgeting Chimeras (PROTACs) have been extensively explored for targeted protein degradation and cancer therapy. However, clinic translation of the conventional small molecular PROTACs is challenged by their unfavorable pharmacokinetic profiles and the systemic toxicity due to on-target but off-tumor protein degradation. Herein we presented a tumor microenvironment-activatable polymeric PROTAC (namely POLYTAC) nanoplatform for tumor-specific PROTAC delivery and combinatory cancer therapy. The POLYTAC nanoparticles were engineered by integrating metalloproteinase-liable poly(ethylene glycol) shell, intracellular acidity-responsive hydrophobic core and reduction-activatable PROTACs into one nanoplatform. The resultant POLYTAC nanoparticles can specifically accumulate at the tumor site and release the PROTACs inside the tumor cells for protein degradation. The POLYTAC nanoparticles can be further engineered for bioorthogonal click reaction-enforced tumor-specific delivery of the PROTACs. In combination with photodynamic therapy, we demonstrated that the bioorthogonal POLYTAC nanoparticles remarkably suppressed tumor growth by synergistically inducing cellular apoptosis of the tumor cells in mouse model of MDA-MB-231 breast cancer. The POLYTAC approach might pave the way for tumor-targeted protein degradation and translation of PROTAC-based cancer therapy.
Individual and regional characteristics associated with changes in mental health before and during the COVID-19 pandemic in South Korea
Authors: Min Jieun , Kwon Dohoon , Lee Whanhee , Kang Cinoo , Park Chaerin , Heo Seulkee , Bell Michelle , Kim Ho 
Published: February 2022

Abstract
Mental health has been a major public health concerns during the COVID-19 pandemic. This study investigated the effects of COVID-19 on mental health and whether individual and regional characteristics are associated with the changes in mental health. We estimated district-specific changes in the prevalence of moderate stress, extreme stress, and depression before and during the COVID-19 pandemic after adjusting for the time trend of mental health outcomes. Then, a meta-regression was conducted to examine the associations between district-level characteristics and changes in mental health due to the pandemic. The prevalence of moderate stress, extreme stress, and depression increased during the pandemic and the increases were more prominent in districts with high population density and in individuals aged 19–59 years, with a high education level, and with high household income. The % with reduced physical activity due to the pandemic were positively associated with increases in stress; while, the % that have mutual trust among neighbors and the number of sports facilities were negatively associated with increases in stress. Local tax per person had a positive association with increase in depression. Our study provides epidemiological evidence into the mental health consequences of the pandemic, which can inform the priority of resource allocation for managing mental health.
Hazard Ranking of Wastewater Sources in a Highly Polluted River in Northern Taiwan by Using Positive Matrix Factorization With Metal Elements
Authors: Hsieh Peiyuan , Lin Huan-Chun , Wang Gen-Shuh , Hsu Yuan-Jeng , Chen Yi-Ju , Wang Tzu-Hui , Wang Ren-De , Kuo Chun-Yu , Wang Di-Wen , Liao Ho-Tang , Wu Chang-Fu 
Published: February 2022

Abstract
Improving water quality is a critical issue worldwide. However, the general parameters (i.e., temperature, pH, turbidity, total solids, fecal coliform, dissolved oxygen, biochemical oxygen demand, phosphates, and nitrates) used in water quality index estimations are unable to identify pollution from industrial wastewater. This study investigated pollution sources at a river pollution hotspot by using the positive matrix factorization (PMF) model. A two-phase sampling collection along a highly polluted river in northern Taiwan was designed. The sampling spots were distributed along the river in Phase I to monitor the spatial variation of river pollutants. A pollution hotspot was determined based on two indices, namely the summed concentrations of elements and a metal index (MI). In Phase II, the river water samples were collected from the hotspot twice daily over 30 consecutive days to monitor the temporal variation of river pollutants. Source profiles of metal elements were obtained during the monitoring period. The Phase II samples were then factorized using the PMF model. Factor profiles retrieved from the PMF model were further assigned to industrial categories through Pearson correlation coefficients and hierarchical classification. The results indicated that the main pollution source was bare printed circuit boards (BPCB), which contributed up to 92% of the copper in the pollution hotspot. In terms of MI apportionment of 11 metals related to health effects, BPCB contributed 91% of the MI in high pollution events. Overall, the MI apportionment provides linkages between pollution level and human health. This is an evidence for policymakers that the regulation of the effluents of BPCB is an effective means to controlling copper concentrations and thus improving water quality in the study area.