bluuebunny/crossref_metadata_2025_split huggingface dataset:
Super-resolution reconstruction based on BM3D and compressed sensing
Authors: Cheng Tao , Jia Dongdong 
Published: June 2022

Abstract
In the various papers published in the field of super-resolution microscopy, denoising of raw images based on block-matching and 3D filtering (BM3D) was rarely reported. BM3D for blocks of different sizes was studied. The denoising ability is related to block sizes. The larger the block is, the better the denoising effect is. When the block size is &gt;40, a good denoising effect can be achieved. Denoising has a great influence on the super-resolution reconstruction effect and the reconstruction time. Better super-resolution reconstruction and shorter reconstruction time can be achieved after denoising. Using compressed sensing, only 20 raw images are needed for super-resolution reconstruction. The temporal resolution is less than half a second. The spatial resolution is also greatly improved.
A case series of bread clip ingestions
Authors: Chuang Fred J , Townend Philip J , Cooper Michelle L 
Published: June 2022

Abstract
The bread clip is one of the most insidious foreign body ingested. The bread clip poses a serious medical danger to patients yet may often fail to manifest itself clinically on initial ingestion. We present a case series of three patients with bread clips ingestions that were managed in the Gold Coast University Hospital, Queensland, Australia between 2020 and 2021. Bread clips are not always readily identifiable depending on imaging and the management of these patients will often require a multidisciplinary approach between the surgeons, gastroenterologists and radiologists.
Urinary retention unveiling deeply embedded multiple leiomyomas in women with Mayer–Rokitansky–Kuster–Hauser syndrome and its successful laparoscopic management: a case-report and literature review
Authors: Jain Namita , Kriplani Isha , Sharma Seema , Hanumantaiya Shaily , Kriplani Alka 
Published: June 2022

Abstract
Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is the second most common cause of primary amenorrhea with an incidence of 1:4000–5000 women. It is characterized by aplasia or hypoplasia of the uterus and the upper two-thirds of the vagina with normal ovaries and tubes and a normal secondary sexual characteristics. The occurrence of leiomyoma is common but it is rare to have leiomyoma in uterine remnant in MRKH syndrome. Although few cases of MRKH syndrome with leiomyoma have been reported in the literature, none presented with urinary retention. Here, we report a case of 28-year-old women who presented with urinary retention that unmasked deeply embedded huge fibroids in pelvis arising from a rudimentary uterine horns and its safe management via laparoscopic approach.
Management of plant central metabolism by SnRK1 protein kinases
Authors: Peixoto Bruno , Baena-González Elena 
Published: June 2022

Abstract
SUCROSE NON-FERMENTING1 (SNF1)-RELATED KINASE 1 (SnRK1) is an evolutionarily conserved protein kinase with key roles in plant stress responses. SnRK1 is activated when energy levels decline during stress, reconfiguring metabolism and gene expression to favour catabolism over anabolism, and ultimately to restore energy balance and homeostasis. The capacity to efficiently redistribute resources is crucial to cope with adverse environmental conditions and, accordingly, genetic manipulations that increase SnRK1 activity are generally associated with enhanced tolerance to stress. In addition to its well-established function in stress responses, an increasing number of studies implicate SnRK1 in the homeostatic control of metabolism during the regular day–night cycle and in different organs and developmental stages. Here, we review how the genetic manipulation of SnRK1 alters central metabolism in several plant species and tissue types. We complement this with studies that provide mechanistic insight into how SnRK1 modulates metabolism, identifying changes in transcripts of metabolic components, altered enzyme activities, or direct regulation of enzymes or transcription factors by SnRK1 via phosphorylation. We identify patterns of response that centre on the maintenance of sucrose levels, in an analogous manner to the role described for its mammalian orthologue in the control of blood glucose homeostasis. Finally, we highlight several knowledge gaps and technical limitations that will have to be addressed in future research aiming to fully understand how SnRK1 modulates metabolism at the cellular and whole-plant levels.
MaizeHEAT UP-REGULATED GENE 1plays vital roles in heat stress tolerance
Authors: Xie Chen , Yang Liu , Jia Guixian , Yan Kang , Zhang Shizhong , Yang Guodong , Wu Changai , Gai Yingping , Zheng Chengchao , Huang Jinguang 
Published: June 2022

AbstractIncreasing temperature is one of the major threats to maize growth and yield globally. Under heat stress conditions, intracellular protein homeostasis is seriously disturbed, leading to accumulation of abnormally folded proteins, especially in the endoplasmic reticulum (ER). Molecular chaperones are vital players in the renaturation process and in preventing protein aggregation. However, heat stress tolerance-associated chaperones are not well documented in maize. Here, we characterized the biological roles of HEAT UP-REGULATED GENE 1 (ZmHUG1) in maize. ZmHUG1 encodes a heat-inducible holdase-type molecular chaperone localized in the ER. Knockout mutant of ZmHUG1 exhibited remarkably enhanced sensitivity to heat stress. Accordingly, the zmhug1 mutant showed severe ER stress under high temperature. MAIZE PRENYLATED RAB ACCEPTOR 1.C1 (ZmPRA1.C1) was identified as a client of ZmHUG1, and heat-induced aggregation of ZmPRA1.C1 was accelerated in the zmhug1 mutant. Furthermore, the expression of ZmHUG1 was rapidly transactivated by ER stress sensor BASIC LEUCINE ZIPPER DOMAIN 60 (bZIP60) when heat stress occurred. This study reveals a ZmHUG1-based thermo-protective mechanism in maize.
The Arabidopsis thaliana–Fusarium oxysporum strain 5176 pathosystem: an overview
Authors: Wang Liu , Calabria Jacob , Chen Hsiang-Wen , Somssich Marc 
Published: June 2022

Abstract
Fusarium oxysporum is a soil-borne fungal pathogen of several major food crops. Research on understanding the molecular details of fungal infection and the plant’s defense mechanisms against this pathogen has long focused mainly on the tomato-infecting F. oxysporum strains and their specific host plant. However, in recent years, the Arabidopsis thaliana–Fusarium oxysporum strain 5176 (Fo5176) pathosystem has additionally been established to study this plant–pathogen interaction with all the molecular biology, genetic, and genomic tools available for the A. thaliana model system. Work on this system has since produced several new insights, especially with regards to the role of phytohormones involved in the plant’s defense response, and the receptor proteins and peptide ligands involved in pathogen detection. Furthermore, work with the pathogenic strain Fo5176 and the related endophytic strain Fo47 has demonstrated the suitability of this system for comparative studies of the plant’s specific responses to general microbe- or pathogen-associated molecular patterns. In this review, we highlight the advantages of this specific pathosystem, summarize the advances made in studying the molecular details of this plant–fungus interaction, and point out open questions that remain to be answered.
Possible jet reorientation in low-frequency radio structures of blazars
Authors: Pajdosz-Śmierciak Urszula , Śmierciak Bartosz , Jamrozy Marek 
Published: June 2022

ABSTRACT
Blazars are active galactic nuclei (AGNs) observed at small viewing angles to the observer’s line of sight; hence most of them are compact sources in the radio regime. At low radio frequencies, we may observe additional extended structures, considered to be lobes propagating directly towards Earth. However, there are rare cases of blazars whose morphologies are interpreted in the framework of an episodic jet activity with a reorientation of the jet axis. In this paper, we aim to find other candidates for sources of this kind and present Low Frequency Array (LOFAR) observations of seven blazars with rare morphologies composed of kiloparsec-scale jets and elongated multihundred kiloparsec-scale features. Based on their radio images and physical parameters, we propose that jets could change the direction of propagation out of the sky plane during the lifetime of at least some of these sources and with such we may observe morphologically different AGN types simultaneously, similar to the previously discovered blazar SBS B1646+499. Several plausible origin scenarios are presented, including fast realignment and precession. We also derive the 144 MHz fluxes of the compact and extended structures, the total radio luminosities, the spectral indices for the diffuse haloes, and the core-dominance parameters. We also discuss the possibility that these objects are actually giant blazars with rare Fanaroff–Riley I (FR I) morphology. The previously discovered blazar SBS B1646+499 should be classified as a giant independently of its inclination with regard to the observer.
EOS-ESTM: a flexible climate model for habitable exoplanets
Authors: Biasiotti L , Simonetti P , Vladilo G , Silva L , Murante G , Ivanovski S , Maris M , Monai S , Bisesi E , von Hardenberg J , Provenzale A 
Published: June 2022

ABSTRACTRocky planets with temperate conditions provide the best chance for discovering habitable worlds and life outside the Solar system. In the last decades, new instrumental facilities and large observational campaigns have been driven by the quest for habitable worlds. Climate models aimed at studying the habitability of rocky planets are essential tools to pay off these technological and observational endeavours. In this context, we present eos-estm, a fast and flexible model aimed at exploring the impact on habitability of multiple climate factors, including those unconstrained by observations. eos-estm is built on estm, a seasonal-latitudinal energy balance model featuring an advanced treatment of the meridional and vertical transport. The novel features of eos-estm include: (1) parametrizations for simulating the climate impact of oceans, land, ice, and clouds as a function of temperature and stellar zenith distance and (2) a procedure (eos) for calculating the radiative transfer in atmospheres with terrestrial and non-terrestrial compositions illuminated by solar- and non-solar-type stars. By feeding eos-estm with Earth’s stellar, orbital, and planetary parameters, we derive a reference model that satisfies a large number of observational constraints of the Earth’s climate system. Validation tests of non-terrestrial conditions yield predictions that are in line with comparable results obtained with a hierarchy of climate models. The application of eos-estm to planetary atmospheres in maximum greenhouse conditions demonstrates the possibility of tracking the snowball transition at the outer edge of the HZ for a variety of planetary parameters, paving the road for multiparametric studies of the HZ.
Modeling the kinematics of globular cluster systems
Authors: Chen Yingtian , Gnedin Oleg Y 
Published: June 2022

ABSTRACT
Globular clusters (GCs) are old massive star clusters that serve as ‘fossils’ of galaxy formation. The advent of Gaia observatory has enabled detailed kinematics studies of the Galactic GCs and revolutionized our understanding of the connections between GC properties and galaxy assembly. However, lack of kinematic measurements of extragalactic GCs limits the sample size of GC systems that we can fully study. In this work, we present a model for GC formation and evolution, which includes positional and kinematic information of individual GCs by assigning them to particles in the Illustris TNG50-1 simulation based on age and location. We calibrate the three adjustable model parameters using observed properties of the Galactic and extragalactic GC systems, including the distributions of position, systemic velocity, velocity dispersion, anisotropy parameter, orbital actions, and metallicities. We also analyse the properties of GCs from different origins. In outer galaxy, ex situ clusters are more dominant than the clusters formed in situ. This leads to the GC metallicities decreasing outwards due to the increasing abundance of accreted, metal-poor clusters. We also find the ex-situ GCs to have greater velocity dispersions and orbital actions, in agreement with their accretion origin.
Are superthin galaxies low-surface-brightness galaxies seen edge-on? The star formation probe
Authors: Narayanan Ganesh , Banerjee Arunima 
Published: June 2022

ABSTRACT
Superthin galaxies (STs) are edge-on disc galaxies with strikingly high planar-to-vertical axes ratios of ∼10–20 with no bulge component, and central surface brightness in the B band &gt; 23 mag arcsec−2 comparable to low-surface-brightness galaxies (LSBs). Although STs and LSBs have similar dynamical, stellar, and atomic hydrogen (H i) masses on an average, it is tricky to conclude if they constitute the same galaxy population, given the edge-on and face-on orientations of the STs and the LSBs, respectively. We systematically study star formation rate (SFR) in a sample of STs and LSBs using SED fitting of photometric data in 10 bands including GALEX: FUV, NUV, SDSS: u,g,r,i,z and 2MASS: J, H, Ks using stellar population synthesis models employing the publicly available software magphys (Multi-Wavelength Analysis of Galaxy Physical Properties). The estimated median SFRs for LSBs and STs are $0.4^{+2.2}_{-0.3}$$ and $0.2^{+0.9}_{-0.2}\, {\rm M}_{\odot }{\rm yr}^{-1}$, respectively. Our calculations indicate that this deficit in the SFR of an ST can be attributed to inclination and opacity effects. Therefore, we conclude that STs and LSBs have equal intrinsic SFR over and above other physical properties, which possibly implies that STs are just LSBs seen in edge-on.
Priors on Lagrangian bias parameters from galaxy formation modelling
Authors: Zennaro Matteo , Angulo Raul E , Contreras Sergio , Pellejero-Ibáñez Marcos , Maion Francisco 
Published: June 2022

ABSTRACT
We study the relations among the parameters of the hybrid Lagrangian bias expansion model, fitting biased auto and cross power spectra up to $k_{\rm max} = 0.7 \, h \, \mathrm{Mpc}^{-1}$. We consider ∼8000 halo and galaxy samples, with different halo masses, redshifts, galaxy number densities, and varying the parameters of the galaxy formation model. Galaxy samples are obtained through state-of-the-art extended subhalo abundance matching techniques and include both stellar mass and star formation rate selected galaxies. All of these synthetic galaxy samples are publicly available. We find that the hybrid Lagrangian bias model provides accurate fits to all of our halo and galaxy samples. The coevolution relations between galaxy bias parameters, although roughly compatible with those obtained for haloes, show systematic shifts and larger scatter. We explore possible sources of this difference in terms of dependence on halo occupation and assembly bias of each sample. The bias parameter relations displayed in this work can be used as a prior for future Bayesian analyses employing the hybrid Lagrangian bias expansion model.
Phenotyping and modeling of root hydraulic architecture reveal critical determinants of axial water transport
Authors: Boursiac Yann , Pradal Christophe , Bauget Fabrice , Lucas Mikaël , Delivorias Stathis , Godin Christophe , Maurel Christophe 
Published: June 2022

Abstract
Water uptake by roots is a key adaptation of plants to aerial life. Water uptake depends on root system architecture (RSA) and tissue hydraulic properties that, together, shape the root hydraulic architecture. This work investigates how the interplay between conductivities along radial (e.g. aquaporins) and axial (e.g. xylem vessels) pathways determines the water transport properties of highly branched RSAs as found in adult Arabidopsis (Arabidopsis thaliana) plants. A hydraulic model named HydroRoot was developed, based on multi-scale tree graph representations of RSAs. Root water flow was measured by the pressure chamber technique after successive cuts of a same root system from the tip toward the base. HydroRoot model inversion in corresponding RSAs allowed us to concomitantly determine radial and axial conductivities, providing evidence that the latter is often overestimated by classical evaluation based on the Hagen–Poiseuille law. Organizing principles of Arabidopsis primary and lateral root growth and branching were determined and used to apply the HydroRoot model to an extended set of simulated RSAs. Sensitivity analyses revealed that water transport can be co-limited by radial and axial conductances throughout the whole RSA. The number of roots that can be sectioned (intercepted) at a given distance from the base was defined as an accessible and informative indicator of RSA. The overall set of experimental and theoretical procedures was applied to plants mutated in ESKIMO1 and previously shown to have xylem collapse. This approach will be instrumental to dissect the root water transport phenotype of plants with intricate alterations in root growth or transport functions.
Early Initiation of Sub−Anesthetic Ketamine Infusion in Adults with Vaso-Occlusive Crises Is Associated with Greater Reduction in Sickle Cell Pain Intensity: A Single Center’s Experience
Authors: Kenney Martha O , Becerra Benjamin , Mallikarjunan Arvind , Shah Nirmish , Smith Wally R 
Published: June 2022

AbstractObjectivesRecurrent, severely painful episodes, known as vaso-occlusive crises (VOCs) are the hallmark of sickle cell disease (SCD) and the primary reason for hospitalization. Opioids have been the gold standard for VOC treatment without significant improvement pain outcomes. To aid analgesia and combat opioid related adverse effects (ORAEs), some SCD clinicians have trialed infusions of sub-anesthetic ketamine along with opioids to treat VOCs. In this retrospective analysis, we compared adult SCD patients who received early vs late adjunctive sub-anesthetic ketamine infusions for VOCs.MethodsWe identified adult SCD patients (age 18–50 years) who presented to Duke University with a VOC and received sub-anesthetic ketamine infusions from July 2015 to June 2019. We assessed both daily opioid consumption (measured as oral morphine milligram equivalents (MME)) and self-reported 0–10 numeric pain ratings (NPR) at 1, 2, and 3 days after infusion initiation, as well as 1 day after discontinuation.ResultsA total of 56 patients were identified with a median age of 30 years. Compared to late administration, early infusion of sub-anesthetic ketamine was associated with a 24.5% (P = .0003) and 25.9% (P = .0006) reduction, respectively, in median NPR at 1 day and 2 days after infusion initiation but did not persist at 3 days following initiation of the infusion. A statistically significant reduction in MME was not observed.ConclusionsIn a nonrandomized study of sickle cell patients with VOCs, early sub-anesthetic ketamine infusion led to greater reduction in subjective pain intensity than late initiation of the infusion. Randomized studies should further explore whether early vs late ketamine infusion improves management of acute SCD pain.
L’ingénierie juridique et le droit des sûretés OHADA
Authors: Tchotchou Petche Kamga Camille , Nfoutcha Georges 
Published: June 2022

Abstract
Practice constantly formulates efficient guarantees, adapted to economic and financial transactions, so much so that it feeds and inspires the law of OHADA security. With this enrichment, OHADA's security law itself becomes an instrument of legal engineering from which the parties can combine security, arranging and enrichen them within the limits set by the OHADA legislator. It can thus be said that the Uniform Act on the organization of security is a veritable “Iceberg”. Its visible part highlights known safety features, while the submerged side contains a host of possibilities for the development of guarantee agreements. You just have to be creative and subtle in order to get the best out of OHADA's safety.
Molecular epidemiology of Porcine Parvovirus Type 1 (PPV1) and the reactivity of vaccine-induced antisera against historical and current PPV1 strains
Authors: Vereecke Nick , Kvisgaard Lise Kirstine , Baele Guy , Boone Carine , Kunze Marius , Larsen Lars Erik , Theuns Sebastiaan , Nauwynck Hans 
Published: June 2022

AbstractPorcine Parvovirus Type 1 (PPV1) contributes to important losses in the swine industry worldwide. During a PPV1 infection, embryos and fetuses are targeted, resulting in stillbirth, mummification, embryonic death, and infertility (SMEDI syndrome). Even though vaccination is common in gilts and sows, strains mainly belonging to the 27a-like group have been spreading in Europe since early 2000s, resulting in SMEDI problems and requiring in-depth studies into the molecular epidemiology and vaccination efficacy of commercial vaccines. Here, we show that PPV1 has evolved since 1855 [1737, 1933] at a rate of 4.71 × 10−5 nucleotide substitutions per site per year. Extensive sequencing allowed evaluating and reassessing the current PPV1 VP1-based classifications, providing evidence for the existence of four relevant phylogenetic groups. While most European strains belong to the PPV1a (G1) or PPV1b (G2 or 27a-like) group, most Asian and American G2 strains and some European strains were divided into virulent PPV1c (e.g. NADL-8) and attenuated PPV1d (e.g. NADL-2) groups. The increase in the swine population, vaccination degree, and health management (vaccination and biosafety) influenced the spread of PPV1. The reactivity of anti-PPV1 antibodies from sows vaccinated with Porcilis© Parvo, Eryseng© Parvo, or ReproCyc© ParvoFLEX against different PPV1 field strains was the highest upon vaccination with ReproCyc© ParvoFLEX, followed by Eryseng© Parvo, and Porcilis© Parvo. Our findings contribute to the evaluation of the immunogenicity of existing vaccines and support the development of new vaccine candidates. Finally, the potential roles of cluster-specific hallmark amino acids in elevated pathogenicity and viral entry are discussed.