bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frecuencia de carcinoma ductal in situ en pacientes del servicio de mastología del hospital nacional de Itauguá-Paraguay en un periodo de enero 2012 a diciembre 2019
Authors: Fernández Ugarte Alba Celia , Báez Lugo Catherine Andrea , Casañas Friedmann Juan Matías , Insfran Fernández Cesar Andrés , Vera Ramos Miguel Angel 
Published: December 2022

El cáncer de mama representa un problema de salud pública debido a su frecuencia y principalmente porque el diagnóstico y tratamiento alteran la calidad de las mujeres afectadas en todas las dimensiones, representa la primera causa de muerte por cualquier tipo de cáncer en la población femenina y su pronóstico depende fundamentalmente de la extensión o de la etapa de la enfermedad en la que se diagnostique y del subtipo tumoral.
La detección del carcinoma ductal in situ es la evidencia de que los programas de salud pública son efectivos; ya que este estadio es curable, he aquí la importancia de realizar este estudio, a fin de determinar la cantidad de pacientes que llegan en estadios precoces, que podrían ser beneficiadas de tratamientos menos cruentos pero curativos.
Se realizó un estudio descriptivo, retrospectivo, de corte trasversal a fin de determinar la frecuencia de carcinoma ductal in situ en pacientes con diagnóstico de cáncer de mama del Servicio de Mastología del HNI del 2012 al 2019. Se encontró un total de 24 pacientes con dicho diagnóstico, que correspondió al 3,1% del total de cánceres diagnosticados. En su mayoría provenientes del Departamento Central, de aproximadamente 50 años, sin antecedentes patológicos familiares ni personales de valor, con patrón histológico de alto grado con comedoconecrosis y receptores hormonales positivos; la mitad recibió tratamiento conservado, y la restante, mastectomía; el 20,83% de las pacientes recibió tratamiento reconstructivo inmediato. Es destacable el bajo porcentaje de detección en estadios precoces del cáncer de mama en nuestro medio.
Brechas sociales en la educación secundaria no presencial en instituciones educativas de una UGEL de la región la libertad
Authors: Hurtado Zavaleta Mg.  Flor Elizabeth 
Published: December 2022

En época de pandemia los estudiantes y docentes no se encontraron en igualdad de condiciones para acceder a una educación no presencial. Cada estudiante recibió el proceso de enseñanza -aprendizaje según características y oportunidades familiares. El objetivo del presente trabajo de investigación fue describir y analizar las brechas sociales en la educación secundaria no presencial en instituciones educativas de una UGEL de la región La Libertad. El tipo de investigación es básica con un diseño no experimental de investigación fenomenológico. Los resultados evidenciaron que el factor económico, la conectividad, el acceso a internet, el desinterés de padres y alumnos en relación al proceso de enseñanza-aprendizaje, la ubicación geográfica del estudiante, el desconocimiento del manejo de entornos virtuales, la preparación académica de los padres, el no contar con equipos tecnológicos, la salud de la familia y la no adecuación a la educación no presencial; constituyeron las diversas brechas sociales que los docentes tuvieron que enfrentar en la educación virtual durante el periodo de pandemia. Se concluye que las brechas sociales han causado limitaciones al acceso del proceso de enseñanza-aprendizaje. Es necesaria una innovación integral en la educación que busque el equilibrio educativo.
La gestión púbica de un gobierno autónomo descentralizado municipal en la dinámica del desarrollo local. El caso de la ciudad de Machala
Authors: Valdiviezo Cacay Manuel Horacio , Luján Johnson Gladys Lola 
Published: December 2022

La gestión pública de los Gobierno Autónomo Descentralizado Municipales (GAD-M) implica la capacidad para formular legislar y ejecutar políticas públicas que impacten en el desarrollo local de las ciudades. Por esto, el objetivo de la investigación: es describir el modelo de gestión pública del gobierno autónomo descentralizado municipal. Su abordaje es cuantitativo, tipo básica, diseño no experimental, enfoque descriptivo, explicativo, predictivo, prospectivo. Técnica de recolección de datos: la encuesta. Muestra no probabilística, aplicada a 110 informantes, integrada por técnicos de 55 áreas departamentales del GAD-M Machala. Resultados: se identifican serias asimetrías de poder entre gestores institucionales. Ausencia de actores productivos, gremiales, organizacionales, resistencia de líderes comunitarios y escasa participación ciudadana en toma decisiones de interés público, afectando la gobernanza; a su vez, el 92% de habitantes desconocen las políticas públicas, ordenanzas y proyectos ejecutados por el GAD-M; el 95% desconoce las fuentes de financiamiento, el 98 % no participan en rendición de cuentas. La propuesta: impostergable necesidad de impulsar mecanismos de participación ciudadana, control social, vigilancia en uso pertinente de inversiones, presupuestos participativos y responsabilidad social, siendo el punto de partida la educación a la ciudadanía sobre derechos instituidos en la Ley Organiza de Participación Ciudadana y Control Social ecuatoriana.
Contribution to the microscopic study of three plant species used in traditional Algerian medicine
Authors: HASSAİNE Sara , EL YEBDRİ Nassima , MEDJAHED Badria , YAZİD Khawla 
Published: December 2022

The present work aims to study the anatomical characteristics of three plant species used in Algeria for their diuretic and antilithiasic properties. Also to summarise the results obtained in detailed drawings of each part studied as well as diagrams with conventional tissue signs.
For this, plant samples were collected from herbalists in the region of Tlemcen (northwestern Algeria). These were leaves and stems of Petroselinum crispum (Apiaceae), leaves of Scolymus hispanicus (Asteraceae), leaves and stems of Marrubium vulgare (Lamiaceae); they were all examined and identified. Cross sections were made and stained using the double staining technique; they were then observed under an optical microscope.
It was generally observed that the parsley leaf did not have any secretory trichomes, and the secretory duct in the midrib was located between the phloem and the lower epidermis. It was also noted that there were no secretory trichomes in the Spanish Scolyme. In addition, branched covering trichomes and secretory trichomes with octacellular head were observed in the leaf of white horehound.
These findings are certainly going to help enrich the rare bibliographic data available on the anatomy of these three species.
Galaxies at a Cosmic Ray Eddington Limit
Authors: Heintz Evan , Zweibel Ellen G. 
Published: December 2022

Abstract
Cosmic rays have been shown to be extremely important in the dynamics of diffuse gas in galaxies, helping to maintain hydrostatic equilibrium, and serving as a regulating force in star formation. In this paper, we address the influence of cosmic rays on galaxies by re-examining the theory of a cosmic ray Eddington limit, first proposed by Socrates et al. and elaborated upon by Crocker et al. and Huang & Davis. A cosmic ray Eddington limit represents a maximum cosmic ray energy density above which the interstellar gas cannot be in hydrostatic equilibrium, resulting in a wind. In this paper, we continue to explore the idea of a cosmic ray Eddington limit by introducing a general framework that accounts for the circumgalactic environment and applying it to five galaxies that we believe to be a good representative sample of the star-forming galaxy population, using different cosmic ray transport models to determine what gives each galaxy the best chance to reach this limit. We show that, while an Eddington limit for cosmic rays does exist, for our five galaxies, the limit either falls at star formation rates that are much larger or gas densities that are much lower than each galaxy’s measured values. This suggests that cosmic ray pressure is not the main factor limiting the luminosity of starburst galaxies.
Does the Streaming Instability Exist within the Terminal Velocity Approximation?
Authors: Zhuravlev V. V. 
Published: December 2022

Abstract
Terminal velocity approximation is appropriate to study the dynamics of a gas–dust mixture with solids tightly coupled to the gas. This work reconsiders its compatibility with physical processes giving rise to the resonant streaming instability in the low-dust-density limit. It is shown that the linearized equations that have been commonly used to study the streaming instability within the terminal velocity approximation actually exceed the accuracy of this approximation. For that reason, the corresponding dispersion equation recovers the long-wavelength branch of the resonant streaming instability caused by the stationary azimuthal drift of the dust. However, the latter must remain beyond the terminal velocity approximation by its physical definition. The refined equations for gas–dust dynamics in the terminal velocity approximation does not lead to the resonant streaming instability. The work additionally elucidates the physical processes responsible for the instability.
Planetary Line-to-accretion Luminosity Scaling Relations: Extrapolating to Higher-order Hydrogen Lines
Authors: Marleau Gabriel-Dominique , Aoyama Yuhiko 
Published: December 2022

Abstract
Aoyama et al. provided scaling relations between hydrogen-line luminosities and the accretion luminosity for planetary-mass objects. These fits should be an improvement over blind extrapolations of stellar relations. The fits go up only to the n = 8 electron energy level, but higher-n Balmer lines have been observed in the near-UV with UVES. We extend the scaling relations to higher-n levels for the Balmer and other series by fitting the fit coefficients (a, b) themselves and extrapolating them. Within the assumption of an accretion shock as the source of line emission, these fits should be robust for accreting planetary-mass objects.
Sputtering Behavior of Rough, Polycrystalline Mercury Analogs
Authors: Biber H. , Brötzner J. , Jäggi N. , Szabo P. S. , Pichler J. , Cupak C. , Voith C. , Cserveny B. , Nenning A. , Mutzke A. , Moro M. V. , Primetzhofer D. , Mezger K. , Galli A. , Wurz P. , Aumayr F. 
Published: December 2022

Abstract
The solar wind continuously impacts on rocky bodies in space, eroding their surface, thereby contributing significantly to the exosphere formations. The BepiColombo mission to Mercury will investigate the Hermean exosphere, which makes an understanding of the precise formation processes crucial for evaluation of the acquired data. We therefore developed an experimental setup with two microbalances that allows us to compare the sputter behavior of deposited thin solid layers with that of real mineral samples in the form of pressed powder. In addition, this technique is used to study the angular distribution of the sputtered particles. Using 4 keV He+ and 2 keV Ar+ ions, the sputter behavior of pellets of the minerals enstatite (MgSiO3) and wollastonite (CaSiO3) is studied, because these minerals represent analogs for the surface of the planet Mercury or the Moon. Pellets of powdered enstatite show significantly lower sputter yields than thin amorphous enstatite films prepared by pulsed laser deposition. 3D simulations of sputtering based on surface topography data from atomic force microscopy show that the observed reduction can be explained by the much rougher pellet surface alone. We therefore conclude that sputter yields from amorphous thin films can be applied to surfaces of celestial bodies exposed to ion irradiation, provided the effects of surface roughness, as encountered in realistic materials in space, are adequately accounted for. This also implies that taking surface roughness into account is important for modeling of the interaction of the solar wind with the surface of Mercury.
Analysis of Helicobacter pylori in Saliva of Patients with Laryngopharyngeal Reflux and Non-Laryngopharyngeal Reflux
Authors: Asyari Ade , Yerizel Eti , Putra Andani Eka , Firdawati Firdawati , Utami Refi Amalia 
Published: December 2022

BACKGROUND : Helicobacter pylori is a gram-negative bacteria known as the causative agent of chronic gastritis, peptic ulcer, gastric adenocarcinoma, and gastric mucosa-associated lymphoid tissue lymphoma. Several studies have correlated H. pylori in the pathogenesis of upper airway diseases. H. pylori can be detected in saliva, oropharyngeal aphthae, nasal and sinus mucosa, secretions from the tympanic cavities, larynx, and pharyngeal lymphoid tissue. The diagnosis of LPR can be made simply by examining saliva.
AIM : The aim of the study is to analyze the presence of H.pylori in the saliva of LPR and non LPR patients.
METHODS : This study is an analytic observational study with a case control design. The research was conducted in the ENT-KL Department of Dr. M. Djamil Hospital, Padang, Indonesia. PCR examination was carried out at the Biomedical Laboratory of the Faculty of Medicine, Andalas University on saliva samples to detect the presence of H.Pylori. The study was conducted on 22 LPR patients and 22 control subjects.
RESULT : LPR patients are more common in women than men, which were 12 women and 10 men. The average age of LPR patients is 43.7 years. The presence of H.pylori in LPR patients was 86.4%, while in the non-LPR group was 50%. After being tested using the Chi-square test, a significant difference was found between the presence of H. Pylori and the incidence of LPR (P = 0.010).
CONCLUSION : There was an increase in the frequency of the presence of Helicobacter Pylori in patients with LPR compared to Non LPR patients after statistical analysis.
The effect of errors in the neutron flux density on the uncertainties of nuclear concentrations of nuclides arising during the calculation of fuel burnup in cells with different neutron spectra
Authors: Pisarev Aleksandr N. , Kolesov Valery V. , Kolesov Dmitry V. 
Published: December 2022

Computational studies have been carried out showing the complex time dependence of uncertainties in nuclear concentrations of various nuclides arising from the propagation of the neutron flux density errors in the burnup calculation process in cells with different neutron spectra on the above errors.
It is found that these uncertainties not only depend on the burnup time in a complex way, but also depend on the spectrum of the cell. The variants of the cell with thermal and fast neutron spectra were considered.
The calculations were performed using the VisualBurnOut program (Kolesov et al. 2009), which makes it possible to estimate these uncertainties arising due to errors in the input parameters of the burnup problem (reaction rates, neutron flux density, etc.).
The influence of the number of calculated burnup points on the results of burnup calculations by the Monte Carlo method was investigated. Uncertainties arising in nuclear concentrations at intermediate calculation steps due to errors in nuclear concentrations appearing at the previous step were taken into account in the calculations.
D’un château à l’autre : là où les anges reculent
Authors: Schüttpelz Erhard , Georget Jean-Louis 
Published: December 2022

Quand on restitue les bronzes du Bénin, les morts non pacifiés du Bénin passent de l’arrière-plan du pillage au premier plan de la restitution réalisée et réclament d’autres droits : les morts du « Passage du milieu », ceux qui leur ont survécu, les esclaves pris dans la guerre et les razzias, ceux qui ont été démembrés dans des sacrifices sanguinaires, et même les citoyens libres du royaume du Bénin qui ont été contraints à l’esclavage. Lorsque les bronzes du Bénin arrivent dans le château du musée de Bénin-City, nous voyons les formes des bronzes d’un autre œil. Nous ne voyons alors plus les ancêtres captifs de la dynastie royale qui aspirent à rentrer chez eux lorsqu’ils sont exposés au musée d’ethnographie. Nous voyons les prisonniers du Bénin, et nous voyons l’aspiration à la domination et la violence assassine qui ont donné naissance aux bronzes.
Du local à l’international : les expériences de l’association Tous les Maquis
Authors: Bricaud Gurvan 
Published: December 2022

Membre fondateur de l’association Tous les Maquis, implantée dans le Val-de-Marne, Gurvan Bricaud revient dans cet article sur différentes actions menées par l’association auprès des enfants et des familles dans différents espaces de vie. Se revendiquant d’une démarche de pédagogie sociale, le retour d’expérience opéré ici offre l’occasion d’appréhender concrètement les fondements méthodologiques et philosophiques de cette approche basée sur une logique de construction « chemin faisant » des projets et des activités développées avec les différents participants.
Des syllabes pour le chant : le psaume au XVI e siècle
Authors: Bettens Olivier 
Published: December 2022

Dans la France du xvi e siècle, la diffusion des idées humanistes n’épargne ni la poésie ni la musique. Deux grands projets vont même servir de vecteur à une véritable révolution dans la manière de concevoir la mise en musique d’un texte : le Psautier de Genève et le Psautier en vers mesurés de Jean-Antoine de Baïf. En dépit de la querelle religieuse, tous deux contribuent à placer la syllabe et la verticalité musicale au centre de l’humanisme musical français, en rupture avec le style mélismatique et plus contrapuntique hérité du siècle précédent.
Des exemplaires multiples de l’obituaire au cœur du conflit entre clercs et laïcs dans la paroisse Saint-Georges de Haguenau (début du XVe siècle)
Authors: Rauner Anne 
Published: December 2022

Le procès-verbal d’un arbitrage prononcé en 1405 et une liste de revendications des Hospitaliers adressée à la fabrique en 1427 témoignent des vives tensions entre curé et fabrique de la paroisse Saint-Georges de Haguenau à propos des obituaires. La paroisse dépendait en effet des Hospitaliers de Dorlisheim, qui nommaient le pléban, au grand dam du Conseil, qui rêvait de voir s’installer un chapitre dans l’église Saint-Georges pour mieux exercer son influence sur la fabrique. Les deux textes apportent la preuve de la tenue de deux exemplaires similaires, en théorie du moins, de l’obituaire, l’un par le curé, l’autre par la fabrique, ainsi que les modalités de leur instrumentalisation par les deux camps pour conserver le contrôle des revenus liés aux anniversaires. C’est donc la redéfinition des relations entre autorités politiques et Église, entre clercs et laïcs, qui est en jeu derrière les querelles liées aux anniversaires.
Les juifs d’Alsace sous le Premier Empire
Authors: Renard Nils 
Published: December 2022

La place du judaïsme alsacien dans l’histoire des guerres napoléoniennes constitue un aspect négligé, tant de l’historiographie du Premier Empire que de celle du judaïsme. L’enjeu représenté par la conscription des juifs d’Alsace et leur participation dans ces guerres est pourtant relativement important dans l’histoire alsacienne, région au cœur des routes militaires sous la Révolution et l’Empire. Cette réalité historique trouve des échos dans la mémoire alsacienne, en particulier dans un roman d’Erckmann-Chatrian, Le Blocus, qui offre un exemple de rencontre entre enjeux historiques bien attestés et mise en récit. Le roman présente l’itinéraire de Moïse, investisseur juif de Phalsbourg, qui reflète les enjeux liés à l’économie de guerre, à travers son rôle de marchand, mais aussi ceux liés à la conscription, puisqu’à la faveur du siège de la ville en 1814, le personnage se trouve au cœur de l’expérience militaire napoléonienne. C’est cette réalité double que nous interrogeons, à travers une étude critique du roman. Nous y identifierons les notions de « juif de guerre » et « juif guerrier », développées dans nos travaux sur la place des juifs dans la guerre et les armées napoléoniennes, et qui permettent une analyse historique et anthropologique du récit proposé. Cette analyse conduira aussi à dégager l’originalité de l’œuvre d’Erckmann-Chatrian et ce qu’elle révèle de la mémoire alsacienne qu’elle entend transmettre.
Classifying ANCA-Associated Vasculitis and Correlating Outcomes Based on Anti-PR3/MPO Serology
Authors: Ekbote Gayatri G. , Negalur Natasha , Tanna Dhaval , Bindroo Muzaffar , Raval Dhiren , Bajad Shruti , Gupta Rajiva , Kazi Wasim 
Published: December 2022

Introduction:
Diagnosis and management of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a challenge for all. Overlapping features in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) make diagnosis sometimes difficult. We aimed to classify clinical features and outcomes of proven AAV according to their serology, viz., anti-PR3/myeloperoxidase (MPO) by the enzyme-linked immunosorbent assay (ELISA).

Materials and Methods:
This was a prospective observational study of a total of 66 patients. This study included all consequent (old and new) AAV patients visiting a tertiary care center in northern India from August 2012 to June 2018. Patients were followed up for a minimum of 6 months. ANCA was done by both immunofluorescence assay and ELISA.

Results and Conclusion:
When compared, serological classification yielded findings similar to clinical counterparts [PR3/MPO vs. GPA/MPA]. The majority [80.3%] of patients were PR3-positive and were GPA clinically. Lung involvement was common in the PR3 group; however, there was no significant difference between the two groups [viz., PR3 and MPO, P = 0.18]. ENT involvement was significantly higher in the PR3 group when compared with the MPO group [P-value=0.009]. The difference in renal involvement in both the groups was not significant [P = 0.28]. Renal biopsy findings were similar in both the PR3/MPO groups. The median follow-up period was 18 vs. 12 months in the PR3 and MPO groups, respectively. Relapse was significantly higher in the PR3 group [P = 0.017]. The PR3 group significantly required rituximab for second induction treatment [P = 0.028]. Eight patients (12.12%) died during the study period. There was no significant difference in mortality, and there was permanent organ damage in both the PR3 and MPO groups. Autoantibody-based classification is supplemental to the clinical segregation of AAV phenotypes.