bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH GAYA KEPEMIMPINAN, PRESTASI KERJA, DISIPLIN KERJA KERJA TERHADAP KINERJA KARYAWAN PT. REZKY RAJA ABADI
Authors: Nasution Habibuddin 
Published: September 2022

Tujuan Penelitian ini adalah untuk mengetahui pengaruh gaya kepemimpinan, prestasi kerja, dan disiplin kerja terhadap kinerja karyawan PT. Rezky Raja Abadi. Penelitian ini menggunakan metode penelitian kuantitatif. Teknik pengumpulan data dilakukan menggunakan kuesioner yang disebarkan kepada karyawan. Populasi penelitian ini meliputi PT. Rezky Raja Abadi yang berjumlah 200 orang. Teknik pengambilan sampel menggunakan teknik Purposive Sampling. Jumlah sampel yang digunakan dalam penelitian ini sebesar 84 orang. Hasil Penelitian menunjukkan bahwa terdapat pengaruh gaya kepemimpinan, prestasi kerja, dan disiplin kerja terhadap kinerja karyawan PT. Rezky Raja Abadi.
Vegetarianism as a socially conditioned phenomenon. A social portrait of a modern vegetarian family with children
Authors: Sviridova T. V. , Fisenko A. P. , Yasakov D. S. , Lazurenko S. B. , Makarova S. G. 
Published: September 2022

The idea of excluding animal products from the diet, affecting families with children, has become extremely popular, embodying fashion trends and belonging to a group of people with similar social orientations and lifestyle. In the situation of increasing prevalence of vegetarianism in the children’s population, there are no studies of lifestyle, style and conditions of raising children by vegetarian parents. At the same time, in practice, there is insufficient awareness of vegetarian parents in a field of adequate diet composition, as well as difficulties in compliance between specialists with vegetarian families.The purpose of the study – to study the socio–psychological characteristics of a modern vegetarian family.Materials and methods. An uncontrolled psychological and pedagogical examination of vegetarian families was conducted. 45 mother-child dyads were included in the study. We studied: psychological characteristics of the personality of the child and parents, reasons for choosing the type of nutrition, the style of upbringing of the child, beliefs about monitoring the health and treatment of the child.Results. The normative variant of cognitive development was established in 15.9 % of vegetarian children, the delayed variant of cognitive development – in 72.7 % of children, the deviant variant of cognitive development – in 11.4 % of children. 52.3 % of vegetarian children can be attributed to a group with a low level of socio-psychological adaptability, 38.6 % of children – to a group with an average level of adaptability, 9.1 % of children had high indicators for this parameter. In 62.2 % of cases, there was a permissive parenting style, in 17.8 % of cases – an inconsistent parenting style, in 13.3 % – an authoritarian parenting style, in 6.7 % – a democratic (authoritative) parenting style.Conclusion. The motive for choosing the concept of vegetarianism has a direct impact on the style of parenting and adherence to the recommendations of specialists. Parents do not focus on the individual, personal and psychological needs of the child when they choosing a diet and parenting style, but are guided by their own motives and beliefs regarding the lifestyle that they consider correct.
Wacana Tata Kelola Kebencanaan: Kajian Pembicaraan Aktor Melalui Analisis Media Sosial Twitter
Authors: Nugroho Sapto Setyo , Pasaribu Daniel 
Published: September 2022

This paper examines the discourse on disaster governance issues in Indonesia. By focusing on discourse analysis, disaster studies can be viewed with a social science perspective and with a discursive governance approach. This paper is also an alternative to the dominant concept of "disaster management" in the previous studies. The study was conducted by searching for primary data on one keyword, namely "Penanggulangan Bencana" on Twitter with Netlytic application – social media text and social network analyzer. Through schemes of text analysis, social cognition and social analysis, the results of data collection and analysis show the dominance of speech and the role of government and the diverse significance of other actors. This discusses the unorganized "double track policy-making" model and disaster-conscious behavior through an internalized "living with disaster" view.
Artificial intelligence to detect the femoral intertrochanteric fracture: The arrival of the intelligent-medicine era
Authors: Liu Pengran , Lu Lin , Chen Yufei , Huo Tongtong , Xue Mingdi , Wang Honglin , Fang Ying , Xie Yi , Xie Mao , Ye Zhewei 
Published: September 2022

Objective: To explore a new artificial intelligence (AI)-aided method to assist the clinical diagnosis of femoral intertrochanteric fracture (FIF), and further compare the performance with human level to confirm the effect and feasibility of the AI algorithm.Methods: 700 X-rays of FIF were collected and labeled by two senior orthopedic physicians to set up the database, 643 for the training database and 57 for the test database. A Faster-RCNN algorithm was applied to be trained and detect the FIF on X-rays. The performance of the AI algorithm such as accuracy, sensitivity, miss diagnosis rate, specificity, misdiagnosis rate, and time consumption was calculated and compared with that of orthopedic attending physicians.Results: Compared with orthopedic attending physicians, the Faster-RCNN algorithm performed better in accuracy (0.88 vs. 0.84 ± 0.04), specificity (0.87 vs. 0.71 ± 0.08), misdiagnosis rate (0.13 vs. 0.29 ± 0.08), and time consumption (5 min vs. 18.20 ± 1.92 min). As for the sensitivity and missed diagnosis rate, there was no statistical difference between the AI and orthopedic attending physicians (0.89 vs. 0.87 ± 0.03 and 0.11 vs. 0.13 ± 0.03).Conclusion: The AI diagnostic algorithm is an available and effective method for the clinical diagnosis of FIF. It could serve as a satisfying clinical assistant for orthopedic physicians.
Optimizing nutrient removal and biomass production of the Algal Turf Scrubber (ATS) under variable cultivation conditions by using Response Surface Methodology
Authors: Gan Xinyu , Klose Holger , Reinecke Diana 
Published: September 2022

This study investigated and optimized the nutrient remediation efficiency of a simple low-cost algal biofilm reactor, the algal turf scrubber (ATS), for wastewater treatment. Combined effects of three cultivation variables—total inorganic carbon, nitrogen-to-phosphorous (N:P) ratio, and light intensity—were examined. The ATS nutrient removal efficiency and biomass productivity were analyzed considering the response surface methodology (RSM). The maximum removal rates of total P and N were 8.3 and 19.1 mg L−1 d−1, respectively. As much as 99% of total P and 100% of total N were removed within 7 days. Over the same period, the dissolved oxygen concentration and pH value of the medium increased. The optimal growth conditions for simultaneous maximum P and N removal and biomass productivity were identified. Our RSM-based optimization results provide new insights into the combined effect of nutrient and light availability on the ATS remediation efficiency and biomass productivity.
Two complementary approaches for efficient isolation of Sertoli cells for transcriptomic analysis
Authors: Petrusová Jana , Manning Jasper , Kubovčiak Jan , Kolář Michal , Filipp Dominik 
Published: September 2022

Sertoli cells (SCs) are the only somatic cells that reside in seminiferous tubules of testis. They directly interact with and support the development of germ cells, thus have an indispensable role in the process of spermatogenesis. SCs first appear in a proliferative state and then, with the initiation of the first wave of spermatogenesis, progress to a mature “nurturing” state which supports lifelong continuous sperm production. During this development, the SC transcriptome must adapt rapidly as obstacles in SC maturation often result in deficiencies in male fertility. Due to its importance in spermatogenesis, a reliable, rapid, and precise method for the isolation of high purity, viable and unadulterated SC has been largely missing. We have developed an improved method for the preparation of a testicular single cell suspension comprised of two alternative protocols to separate SCs from the rest of the testicular cells by FACS. The first sorting scheme is based on their co-expression of surface specific markers, FSHr and Occludin-1, while the second focuses on the co-staining of SCs with FSHr-specific antibody and Hoechst 33342, which discriminates DNA content of testicular cells. The entire procedure can be completed in less than 3 h which permits the analysis of the development-related transcriptional profile of these cells. Notably, our comparative study showed that this method resulted in a SC transcriptome that is largely comparable to SCs which were briskly isolated due to their cell-specific expression of fluorescent protein. Interestingly, we also show that SCs sorted as FSHr+Occludin+ cells contained a tangible portion of transcripts from all types of testicular germ cells. Sorting of SCs according to their 2C DNA content significantly reduced the presence of these transcripts, thus seems to be the most suitable approach for accurate determination of the SC transcriptome. We believe that these novel approaches for the isolation of SCs will assist researchers in the elucidation of their function as well as their role in spermatogenesis and disorders related to male infertility.
Sodium–glucose cotransporter-2 inhibitor alleviated atrial remodeling in STZ-induced diabetic rats by targeting TLR4 pathway
Authors: Zhan Xiaoping , Cheng Lijun , Huo Ning , Yu Lin , Liu Changle , Liu Tong , Li Guangping , Fu Huaying 
Published: September 2022

PurposeThe mechanism of sodium–glucose cotransporter-2 inhibitor (SGLT-2i) reducing the incidence of atrial fibrillation remains unclear. We hypothesize that sodium–glucose cotransporter-2 inhibitor alleviated atrial remodeling in STZ-induced diabetic rats by targeting TLR4 pathway.MethodsA total of 42 rats were randomly assigned into three groups: control group (CON group); diabetes group (DM group): diabetes mellitus rats were established by 65 mg/kg streptozotocin (STZ) intraperitoneal injection; and diabetes + dapagliflozin group (DM + DAPA group): diabetic rats were given DAPA gavage administration (DAPA 2mg/kg/d for 4 weeks by gavage administration), 14 rats in each group. Epicardial multiple-lead recording and intracardiac electrophysiology studies were performed to investigate the electrical remodeling in the heart and the atrial fibrillation inducibility in each group. Western blot analysis and real-time PCR were used to determine the protein and mRNA expression of toll-like receptor 4 (TLR4), interleukin receptor-associated kinase 1 (IRAK1), tumor necrosis factor receptor-associated factor 6 (TRAF6), nuclear factor-kappa B (NF-κB), and type I collagen (collagen I).ResultsCompared with rats in CON group, rats in DM group showed marked myocardial fibrosis, ectopic pacing excitement, reduced conduction velocity, decreased cardiac function. TLR4/IRAK1/TRAF6/NF-κB, collagen I proteins expressions and incidence of atrial fibrillation (27.3%) were increased in DM group. Parts of these changes were reversed by treatment of DAPA. Incidence of atrial fibrillation was decreased in DM + DAPA group (2.8%).ConclusionsSGLT-2i dapagliflozin may prevent diabetic rats' atrial remodeling and reduce the inducibility of atrial fibrillation partly by targeting TLR4/IRAK1/TRAF6/NF-κB inflammatory pathway.
D-dimer, BNP/NT-pro-BNP, and creatinine are reliable decision-making biomarkers in life-sustaining therapies withholding and withdrawing during COVID-19 outbreak
Authors: Smadja David M. , Fellous Benjamin A. , Bonnet Guillaume , Hauw-Berlemont Caroline , Sutter Willy , Beauvais Agathe , Fauvel Charles , Philippe Aurélien , Weizman Orianne , Mika Delphine , Juvin Philippe , Waldmann Victor , Diehl Jean-Luc , Cohen Ariel , Chocron Richard 
Published: September 2022

BackgroundThe decision for withholding and withdrawing of life-sustaining treatments (LSTs) in COVID-19 patients is currently based on a collegial and mainly clinical assessment. In the context of a global pandemic and overwhelmed health system, the question of LST decision support for COVID-19 patients using prognostic biomarkers arises.MethodsIn a multicenter study in 24 French hospitals, 2878 COVID-19 patients hospitalized in medical departments from 26 February to 20 April 2020 were included. In a propensity-matched population, we compared the clinical, biological, and management characteristics and survival of patients with and without LST decision using Student's t-test, the chi-square test, and the Cox model, respectively.ResultsAn LST was decided for 591 COVID-19 patients (20.5%). These 591 patients with LST decision were secondarily matched (1:1) based on age, sex, body mass index, and cancer history with 591 COVID-19 patients with no LST decision. The patients with LST decision had significantly more cardiovascular diseases, such as high blood pressure (72.9 vs. 66.7%, p = 0.02), stroke (19.3 vs. 11.1%, p &lt; 0.001), renal failure (30.4 vs. 17.4%, p &lt; 0.001), and heart disease (22.5 vs. 14.9%, p &lt; 0.001). Upon admission, LST patients were more severely attested by a qSOFA score ≥2 (66.5 vs. 58.8%, p = 0.03). Biologically, LST patients had significantly higher values of D-dimer, markers of heart failure (BNP and NT-pro-BNP), and renal damage (creatinine) (p &lt; 0.001). Their evolutions were more often unfavorable (in-hospital mortality) than patients with no LST decision (41.5 vs. 10.3%, p &lt; 0.001). By combining the three biomarkers (D-dimer, BNP and/or NT-proBNP, and creatinine), the proportion of LST increased significantly with the number of abnormally high biomarkers (24, 41.3, 48.3, and 60%, respectively, for none, one, two, and three high values of biomarkers, trend p &lt; 0.01).ConclusionThe concomitant increase in D-dimer, BNP/NT-proBNP, and creatinine during the admission of a COVID-19 patient could represent a reliable and helpful tool for LST decision. Circulating biomarker might potentially provide additional information for LST decision in COVID-19.
Neuroprotective effect of remote ischemic preconditioning in patients undergoing cardiac surgery: A randomized controlled trial
Authors: Zhu Shouqiang , Zheng Ziyu , Lv Wenying , Ouyang Pengrong , Han Jiange , Zhang Jiaqiang , Dong Hailong , Lei Chong 
Published: September 2022

BackgroundThe neuroprotective effect of remote ischemic preconditioning (RIPC) in patients undergoing elective cardiopulmonary bypass (CPB)-assisted coronary artery bypass graft (CABG) or valvular cardiac surgery remains unclear.MethodsA randomized, double-blind, placebo-controlled superior clinical trial was conducted in patients undergoing elective on-pump coronary artery bypass surgery or valve surgery. Before anesthesia induction, patients were randomly assigned to RIPC (three 5-min cycles of inflation and deflation of blood pressure cuff on the upper limb) or the control group. The primary endpoint was the changes in S-100 calcium-binding protein β (S100-β) levels at 6 h postoperatively. Secondary endpoints included changes in Neuron-specific enolase (NSE), Mini-mental State Examination (MMSE), and Montreal Cognitive Assessment (MoCA) levels.ResultsA total of 120 patients [mean age, 48.7 years; 36 women (34.3%)] were randomized at three cardiac surgery centers in China. One hundred and five patients were included in the modified intent-to-treat analysis (52 in the RIPC group and 53 in the control group). The primary result demonstrated that at 6 h after surgery, S100-β levels were lower in the RIPC group than in the control group (50.75; 95% confidence interval, 67.08 to 64.40 pg/ml vs. 70.48; 95% CI, 56.84 to 84.10 pg/ml, P = 0.036). Compared to the control group, the concentrations of S100-β at 24 h and 72 h and the concentration of NSE at 6 h, 24 h, and 72 h postoperatively were significantly lower in the RIPC group. However, neither the MMSE nor the MoCA revealed significant between-group differences in postoperative cognitive performance at 7 days, 3 months, and 6 months after surgery.ConclusionIn patients undergoing CPB-assisted cardiac surgery, RIPC attenuated brain damage as indicated with the decreased release of brain damage biomarker S100-β and NSE.Clinical trial registration[ClinicalTrials.gov], identifier [NCT01231789].
Novel dry pericardiocentesis: Transvenous puncture of the right ventricle with the back end of a 0.014-inch PTCA guidewire and a 1.8 Fr microcatheter
Authors: Qin Hua-Di , Gao Hui , Gao Jie , Hou Lin , Shao Xiang-Seng , Tang Jing-Wei , Qin Chun-Chang 
Published: September 2022

BackgroundDry transthoracic pericardiocentesis is challenging and carries the risk of right ventricle (RV) or coronary artery injury. The RV can usually control bleeding automatically. For example, most perforations of the RV caused by pacemaker leads are treated without open surgery. Thus, we performed a transvenous puncture of the RV for dry pericardiocentesis with the back end of a 0.014-inch percutaneous transluminal coronary angioplasty (PTCA) guidewire and a 1.8 Fr microcatheter.MethodsThe back end of a 0.014-inch PTCA guidewire within a 1.8 Fr microcatheter was used to transvenously punctured through the middle of the acute margin of the RV into the pericardial space in 12 Yorkshire swine and 5 beagles. PTCA balloons of different diameters were used to dilate the puncture holes for 15 min under anticoagulation in all the animals to assess the ability of the RV to control the bleeding. Then, for 3 days, the puncture hole was dilated by a 6 Fr catheter in 9 swine and 5 dogs.ResultsThe puncture was successful in all the animals. After withdrawal of the 2.5-mm balloon or the 6 Fr catheter, none of the animals exhibited pericardial effusion, as observed by echocardiography. There was no sustained ventricular arrhythmia or other complications. All the animals survived.ConclusionTransvenous puncture of the right ventricle with the back end of a 0.014-inch PTCA guidewire and 1.8 Fr microcatheter may be feasible and have a good safety margin.
Change of moraine-dammed glacial lakes and simulation of glacial lake outburst flood in the Yi’ong Zangbo River basin
Authors: Wang Qi , Duan Hongyu , Liu Na , Du Zhishui , Wang Pan , Yi Bo , Xu Jun , Huang Jian , Zhang Yuan , Yao Xiaojun 
Published: September 2022

Glacial lake outburst floods (GLOFs) are a serious potential threat to the safety of life and property in downstream areas. In this study, moraine-dammed glacial lakes in the Yi’ong Zangbo River basin were recognized based on Landsat ETM+/TM/OLI images in 2000 and 2019. Also, GLOFs for the Jionglaco, the largest glacial lake in this basin, were simulated using the one-dimensional hydrodynamic model. The results show that the total number and area of moraine-dammed glacial lakes in this basin increased by 10 (10.52%) and 5.49 km2 (48.24%) from 2000 to 2019, respectively, in which the area of the Jionglaco increased by 3.22 km2. The peak discharge at the breach outlet for five scenarios with different combinations of breach width (80 and 120 m), depth (2.5 and 5 m), and flood time (1.5 and 3 h) are 489 , 1,327.43, 444.32, 617.47, and 1,570.61 m3/s. With the addition of baseflow in the river, the peak discharge at bridge site 15,138.93 km from Jionglaco, is 1,040.89, 1,724.00, 1,024.85, 1,162.25, and 1,990.52 m3/s. The combination of baseflow in river and the GLOF discharge results in an increasing peak discharge in the further downstream region. However, the arrival of peak discharge in downstream areas is delayed, which increases the chances of people escaping.
Variability of sea salt and methanesulfonate in firn cores from northern Victoria Land, Antarctica: Their links to oceanic and atmospheric condition variability in the Ross Sea
Authors: Ro Seokhyun , Hong Sang-Bum , Kim Joo-Hong , Han Yeongcheol , Hur Soon Do , Kang Jung-Ho , Kim Songyi , Lim Changkyu , Chang Chaewon , Moon Jangil , Kim Seong-Joong , Hong Sungmin 
Published: September 2022

The potential ice core proxies of variability in oceanic and atmospheric conditions over the Ross Sea were evaluated. This study examined sea salt sodium (ss–Na+) and biogenic sulfur (methanesulfonate, MS–) records, covering 23 years between 1990 and 2012, from two firn cores drilled on the Styx Glacier plateau (SGP), northern Victoria Land, East Antarctica, to examine the potential links between those records and datasets for various climate variables. The comparison showed that the interannual variability of the ss–Na+ record is closely related to Pacific–South American mode 2 (PSA2) in the Ross Sea sector, exhibiting an increased ss–Na+ flux, owing most likely to more frequent penetration of maritime air masses from the western Ross Sea to the SGP when the winter/spring PSA2 mode becomes more pronounced. The observed MS– record revealed statistically significant positive correlations with the changes in the summertime chlorophyll a concentration in the Ross Sea polynya (RSP) and wind speed in the southern Ross Sea region. This indicates the dominant role of a combination of changes in the summertime primary productivity and wind speed over the RSP in modulating the MS– deposition flux at the SGP. These results highlight the suitability of the ss–Na+ and MS– records from the SGP as proxies for characterizing the dominant patterns of variability in oceanic and atmospheric conditions and their underlying mechanisms on interannual and longer timescales beyond the instrumental limits over the Ross Sea region.
Late Quaternary faulting and paleoearthquakes along the northern section of the Bayanhaote fault and their implications for regional seismotectonics
Authors: Chen Guihua , Li Zhongwu , Huang Xiongnan 
Published: September 2022

Analysis of the late Quaternary activity and paleoseismicity of the Bayanhaote fault is critical because it is part of the frontier of the propagating Tibetan Plateau and the boundary between the Alxa and Ordos blocks, and the development of a regional seismotectonic model surrounding the Helan Mountains is crucial. We studied offset landforms and paleoearthquakes along the northern section of the Bayanhaote fault and found that it deformed dextrally, with a slight reverse slip to the east. A channel and a deluvial edge on the alluvial terrace, aged between 56.28 ± 4.04 ka and 82.2 ± 5.78 ka, are right-laterally offset and a sag pond formed on the east side of the fault scarp. We calculated a dextral slip rate of 1.0–2.4 mm/a. Three surface-rupturing paleoearthquakes were discovered in the reversely offset strata in a trench south of Sumutu village. We infer that these three earthquakes might be a portion of surface-rupturing earthquakes by comparing them with documented paleoearthquake data along the southern half of the Bayanhaote fault. We established a regional seismotectonic model around the Helan Mountains using our new and published geological and geophysical data. The seismic risk along the dextral Bayanhaote fault to the west of the Helan Mountains is also substantial. The dextral Bayanhaote fault west of the Helan Mountains and the normal fault system in the east constitute the active boundary belt between the Alxa and Ordos blocks.