bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ischemic stroke in the debut of coronavirus infection
Authors: Nadezhdina M. V. , Prokhorova T. V. 
Published: March 2022

Introduction. The risk of ischemic stroke (IS) on the background of COVID-19 is about 5% and is associated with a more severe course of coronavirus infection (CVI).The aim of the study was to identify risk factors and clinical features of IS in a debut of CVI in neurological inpatients.Materials and methods. A prospective analysis of the neurological status, clinical, biochemical parameters, ultrasound examination of brachiocephalic vessels, computed tomography (CT) of the brain and the lungs was performed in 15 patients in the acute period of IS with a later detected PCR SARS-Cov-2.Results. The average age of patients is 70.3±7 years. Risk factors for IS in the debut of CVI: stenosis of 30-50% of the internal carotid artery (ICA), arterial hypertension in 100%; dyslipidemia in 86.7%; type 2 diabetes mellitus in 46.7%; coronary heart disease in a third of cases. Lung damage according to CT did not exceed 50%. There is no clear correlation between IS severity, its localization and degree of respiratory failure. The localization of IS corresponded to the side of ICA stenosis. The young patient had signs of antiphospholipid syndrome, extravasal compression of both vertebral arteries, hypoplasia of the posterior connective artery corresponding to the focus of extensive infarction in the middle cerebral artery basin.Discussion. A feature of the debut of CVI in the acute period of IS was the absence of subfebrility in the presence of increased CRP, thrombocytopenia, hyperfibrinogenemia, and a more than 3-fold increase in D-dimer, indicating early activation of platelet-vascular hemostas. The fact of the development of IS according to the side of the stenotic vessel is explained by the manifestation of latent organic pathology under the influence of CVI, thanks to the affinity of SARS-CoV-2 for the ACE2 receptors present in the vascular endothelium.Conclusion. In connection with the present epidemiological situation, the fact of the onset of IS in CVI without hyperthermia suggests an early PCR test with subsequent adequate treatment of CVI in a specialized institution together with neurologists.
Clinical case of a patient at risk of perioperative recurrence of takotsubo cardiomyopathy
Authors: Volkov E. V. , Batchaeva L. H. , Phisher V. V. , Chernysheva S. G. 
Published: March 2022

Introduction.Takotsubo syndrome is a new nosological form of acquired cardiomyopathy characterized by transient left ventricular dysfunction in response to physical or psychoemotional stress, clinically and electrocardiographically resembling acute coronary syndrome. Takotsubo cardiomyopathy is a form of stress cardiomyopathy simulating acute myocardial infarction with electrocardiographic and biochemical changes. Despite a large number of publications, there is no definitive understanding of the etiopathogenesis, clinical picture, treatment, as well as measures to prevent the development of takotsubo cardiomyopathy. With the manifestation of takotsubo cardiomyopathy in the perioperative period, the clinical picture may be even less specific, which inevitably leads to diagnostic difficulties. Given that the main trigger of the disease is stress, the development of this disease is an urgent problem of anesthesiology and intensive care. In addition, there is a problem of managing patients with a history of takotsubo cardiopathy, if they need surgical interventions.The aim of the workwas to prove the effectiveness of a number of approaches (premedication with the use of barbiturates and α2-adrenoceptor agonists; monitoring the depth of anesthesia; administration of narcotic analgesics in continuous infusion; use of local anesthetics for skin anesthesia; multimodal anesthesia in the postoperative period) to the perioperative management of patients with a high risk of CT recurrence.Materials and method.We present a clinical case demonstrating the possible tactics of perioperative management of a patient with a history of CT that manifested during anesthesia when a follow-up benefit was needed. The clinical picture is described, the results of instrumental and laboratory investigations indicating a correct CT diagnosis are presented.Results.An individual strategy for perioperative management of the patient was developed and implemented, which made it possible to avoid a CT recurrence. Discussion. The etiopathogenesis of the disease and analysis of the few literature sources on the topic allow us to propose a number of approaches to the perioperative management of patients at risk of recurrence of CT.Conclusions.A number of approaches (premedication with barbiturates and α 2-adrenoceptor agonists; anesthesia depth monitoring; administration of narcotic analgesics in continuous infusion mode; use of local anesthetics for skin anesthesia; multimodal anesthesia in the postoperative period) to perioperative management of patients with high risk of CT recurrence were demonstrated to be successful.
Analysis of treatment outcomes of patients with colorectal cancer in the COVID-19 pandemic
Authors: Shishkina G. A. , Topuzov E. G. , Petryashev A. V. , Erokhina E. A. , Plotnikov U. V. , Serkova O. P. , Kravchenko M. B. , Isaev S. V. 
Published: March 2022

Introduction. The COVID-19 pandemic has made adjustments to the health care system. Among other things, it has led to shortened hospital stays. In the surgical treatment of patients with colorectal cancer (CRC), the possibility of reducing the bed-day is limited. The aim of the study was to evaluate the results of treatment of CRC patients during and before the pandemic new coronavirus infection. Material and methods. We analyzed the results of treatment of patients with CRC who were treated at the Oppel Hospital Surgery Clinic in 2015 and 2020. Group A included 58 patients treated in 2020, Group B included 44 patients treated in 2015. Patients with stage II disease predominated in both groups: in group A — 31 patients (53.4%), in group B — 19 (43.2%). Results. The average period of hospitalization in the patients of the group A was 12 days, in the group B — 16 days in the patients with uncomplicated postoperative period, in case of complications — 31 days. In group B 47.7% of surgical interventions were performed using laparoscopic techniques, in group A this index was 74.1%. In Group A complications in the early postoperative period were detected in 8 patients (13.8%). In group B complications were diagnosed in 10 patients (22.7%). The incidence of anastomosis failure tended to decrease in group A. In group B six patients (85.7%) who developed this complication required repeated surgical treatment, and in group A only two patients (50%). Discussion. The results demonstrate the effectiveness of the recommendations for perioperative management of patients with CRC and prevention of anastomosis failure. Conclusion. Based on the results obtained, we can say that the quality of surgical care for patients with CRC was avoided during the pandemic. The implementation of research recommendations in this area has helped to reduce the incidence of serious postoperative complications (anastomosis failure).
PERSEPSI WISATAWAN TERHADAP MAKANAN BERBAHAN DASAR SINGKONG BERACUN (ENBAL) PADA DESTINASI WISATA KABUPATEN MALUKU TENGGARA
Authors: Ubjaan Jusak , Wokanubuna Paulina 
Published: March 2022

Tujuan penelitian ini adalah untuk mengetahui dan mendeskripsikan persepsi wisatawan terhadap enbal sebagai pangan lokal dan oleh-oleh khas daerah yang berbahan dasar singkong beracun di Kabupaten Maluku tenggara, Provinsi Maluku. Metode penelitian yang digunakan adalah deskriptif kuantitatif dengan data kuesioner yang dianalisis berdasarkan skala Likert. Untuk mengetahui dan mengidentifikasi karakteristik dari variabel maka digunakan analisis univariat dengan bantuan tabulasi frekuensi. Jenis populasi adalah infinit population yakni wisatawan domestik yang datang selama bulan November – Desember Tahun 2020 di destinasi wisata kabupaten Mluku Tenggara dan kota Tual. Sementara penentuan ukuran sampel menggunakan rumus Lemeshow yang hasilnya sebesar 73 responden. Hasil analisis data menunjukkan persepsi wisatawan terhadap “kualitas makanan” khususnya enbal sebagai pangan lokal dan oleh-oleh khas daerah Kabupaten Maluku tenggara mencapai nilai mean 4,1 atau kategori baik. Demikian juga persepsi wisatawan terhadap “keamanan pangan” khususnya enbal sebagai pangan berbahan dasar singkong beracun, dimana hasil analisis menunjukkan persepsi responden berada pada nilai mean 4,24 atau kategori baik. Umumnya responden berpendapat bahwa enbal sebagai makanan lokal yang telah dikonsumsi secara turun temurun oleh masyarakat Kepulauan Kei, kabupaten Maluku Tenggara dan Kota Tual telah diolah dengan baik sehingga gurih dan aman dikonsumsi.
The constitutional test of necessity: problem statement
Authors: Dolzhikov A. V. 
Published: March 2022

The subject-matter of the research is the constitutional test of necessity. This element of proportionality could be found in doctrine and case-law in the form of metaphors. The necessity as a prong of proportionality consists in testing the available alternatives in comparison with the measures that the legislator has chosen to achieve public aims. The notion of a least restrictive means can be used as a synonym for this element of proportionality. Although this term is cumbersome, it more precisely defines the nature of constitutional litigation, where the admissibility of interference with fundamental rights is assessed.The purpose of the research is to argue that this element of proportionality implies the assessment of the least restrictive alternatives for the rights-holder in order to achieve the goal chosen by the legislator.The methodology of research includes the method of analogy. Accordingly, the analogical reasoning is used in constitutional adjudication when testing necessity of legislative measures, but not the methods of logical subsumtion or judicial balancing. The sources of such analogy can be the rules of international law, ordinary legislation and comparative legal materials.The main results of the research and the scope of their application. The expression necessity is widely used in international law and ordinary legislation. Such approaches are relevant to constitutional adjudication. Thus, the ultima ratio principle, which initially appears in criminal and administrative law, acquires universal application in constitutional justice. This criterion, which requires the use of the most severe legal measures only as a last resort, with the ineffectiveness of softer alternatives, can be extended to the constitutionalization of other branches of legislation.The test of necessity, which is often expressed in metaphors, in the case-law of constitutional justice is based on the method of analogy. In the decisions of the constitutional justice bodies, the least restrictive means are often mentioned in comparison with those which were originally chosen by the legislator. At the same time, the discovered alternatives should be equally or at least minimally suitable in comparison with the existing legislative solutions. Comparative law, international law, or ordinary legislation are often an auxiliary source for constitutional judges to identify and formulate least restrictive alternatives.Conclusions. The value of the analogical reasoning, including the appeal of constitutional justice to comparative law materials, lies in the possibility of identifying some experimental legal regimes. Moreover, the perception of specific alternatives, their clarification or modification remains within the discretionary powers of the legislature. Thus, avoiding the well-known counter-majoritarian difficulty, constitutional justice conducts a dialogue with the parliament, and in the end, contributes to the optimal implementation of fundamental rights.
Freedom of thought, speech and expression: some problems of formulation and determining boundaries in relation to the impact of a religious factor
Authors: Idrisov H. V. 
Published: March 2022

The subject of study. The article examines certain aspects to realize freedom of thought and expression, as well as the acceptable limits. Freedom of thought, speech and expression issues are considered separately in the context of the religious component, its characteristics in the Islamic religion. The provisions of the main sources in the Muslim system of law – the Holy Quran and the Sunnah of the Prophet and Messenger of Muhammad (May Allah bless him) have been studied in sufficient details. The legal analysis on the issues under consideration was carried out based on doctrinal opinions, the current Russian and international legal acts, judicial practice, including the practice of the European Court of Human Rights. The article describes extremism through the prism of freedom of thought, speech and expression. It is noted that extremist activity is one of the consequences of misinterpretation, true awareness and perception of freedom of thought, speech and expression.The purpose of the study. The main purpose of the study is to clarify the origins of conflicts in the process of realizing freedom of thought, speech and expression, and substantiate the hypothesis that freedom of thought, speech and expression should have certain boundaries, especially in context of the influence of the religious factor.The methodology of the study. The study is based on a dialectical approach to the disclosure of legal phenomena and processes using general scientific methods (systemic method, logical method, method of analysis and synthesis) and special scientific methods. Among the latter there are formal legal method, linguistic method, comparative legal method, which have found their application in the legal analysis to realize freedom of thought, speech and expression.Conclusions.As a result, it is emphasized that freedom of thought, speech and expression is the achievement of modern mankind, one of the foundations of a democratic system and an element of civil society. The state-guaranteed opportunity for individuals to exercise these freedoms in society is a guarantee of a "healthy" society in the legal sense. However, as practice shows, unlimited freedom leads to its abuse, thereby infringing on the freedoms of other individuals and therefore, freedom of speech and its expression presupposes the existence of boundaries outlined by the state in the interests of society. The specifics of freedom of thought, speech and expression in the Muslim system of law based on the Holy Quran and the Sunnah of the Prophet (May Allah bless him), is that this freedom ends where the border line begins, designated by the law of the Most High.
Abruptio placenta
Authors: Aparna G. , Anupama D. 
Published: March 2022

Background: Abruptio placenta is defined as preterm separation of normally implanted placenta and causes high maternal and neonatal morbidity and mortality. The present study was done to determine the risk factors for abruption planceta and to evaluate its impact on perinatal and maternal outcomes. Materials & Methods: This retrospective study was carried on 135 cases of Abruptio placenta between January 2019 and September 2020 at Govt. Medical College & Hospital, Nizamabad after obtaining ethical clearance from the institution. In all cases risk factors, maternal and fetal outcome were recorded. The results of studies were recorded in percentage and frequencies and analyzed by SPSS-16 software. Results: The total number of deliveries from January 2019 and September 2020 at Govt. Medical College & Hospital, Nizamabad were 13600, out of which 135 cases were found to be Abruption. The Incidence of Abruptio placenta was 1%. It was most common in the women of age group 25-30 yrs. We found 25% of patients were associated with severe preeclampsia & eclampsia, 23% patients with chronic hypertension and 33.42% patients with normotensive. DIC occurred in 25% of cases & PPH accounts for 28% of the maternal complications.
Man and Coastal Biodiversity
Authors: Gole Prakash 
Published: March 2022

Humans play a critical role in conservation of biodiversity which is a diverse and multifaceted subject. This article highlights the close relationship between the lives of the people and the coastal ecosystem on which their lives depend on. The socio-economic study of the lives of these coastal people is integral to plan conservation of these regions.
A detailed study of the different communities like fishermen, traders, cultivators etc. and their use of natural resources for their livelihoods are elaborated upon. Data on education, occupation and dependency on natural resources for food, water, fuel, timber for boat building etc. were examined. The author also discusses traditional sustainable practices of fishing and the challenges faced by the fishing community in recent times.
Об одномподходек решению нелинейной краевой задачи для интегро-дифференциального уравнения Фредгольма
Authors: Mynbayeva S.T. , Karakenova S.G. 
Published: March 2022

A nonlinear boundary value problem for a Fredholm integro-differential equation is considered. The interval where the problem is considered is partitioned and the values of a solution to the problem at the left endpoint of the subintervals are introduced as additional parameters. The introduction of additional parameters gives initial values at the left endpoints of subintervals for new unknown functions. The considered integro-differential equation is reduced to a special Cauchy problem with parameters for a system of integro-differential equations. If this problem is solvable, then its solution can be represented using the introduced parameters and known values of the integro-differential equation. By substituting these representations into the boundary condition and the continuity conditions of the solution at the interior partition points, a system of nonlinear algebraic equations in the introduced parameters is constructed. The solvability of the boundary value problem is reduced to that of the system of algebraic equations. The conditions for the existence of a solution to the auxiliary system of algebraic equations are established.
Рассматривается нелинейная краевая задача для интегро-дифференциа-льного уравнения Фредгольма. Интервал где рассматривается задача делится на части и зна-чения решения в начальныхточках подинтервалов вводятся в качестве дополнительных па-раметров.Введение дополнительных параметров дает начальные условия в левых точках по-динтервалов для новых неизвестных функций. Рассматриваемое интегро-дифференциальное уравнение сводится к специальной задаче Коши с параметрами для системы интегро-дифференциальных уравнений. Если эта задача разрешима, то ее решение можно предста-вить с помощью введенных параметров и известных величин интегро-дифференциального уравнения. Подставляя представление решения в краевое условие при соответствующих зна-чениях и условия непрерывности решения во внутренних точках разбиения, составляется си-стема нелинейных алгебраических уравнений относительно введенных параметров. Разрешимость нелинейной краевой задачи сводится к разрешимости системы алгебраических уравнений. Установлены условия существования решения вспомогательной системы нели-нейных алгебраических уравнений.
On the use of certain methodological techniques in purposes of forming communicative competence in the context of teachingRussian language at the university
Authors: Тогжанова Л.К. 
Published: March 2022

Статья посвящена особенностям формирования коммуникативной компетенции у студентов при обучении русскому языку в неязыковом вузе.В ней рассматриваются понятие «коммуникативная компетенция» и комплекс методов, спо-собствующих ее формированию. Предлагается интегрированный подход, представляющий собой методическую комбинацию различных продуктивных и активных методов обучения.
The article is devoted to the features of the formation of communicative competence among students in teaching Russian in a non-linguistic university. It examines the concept of ―communicative competence‖ and a set of methods that contribute to its formation. An integrated approach is proposed, which is a methodological combination of various productive and active teaching methods.
Environmental Compliance Reactions to R & D Practices and Intellectual Capital: A Worldwide Evidence
Authors: Alber Nader , Saleh Amr 
Published: March 2022

Our ecosystem and mainly our natural resources represent a vital ecological portfolio. Environment is good for business at a time business is not keen to invest in compliance measures. Sustaining the environment is costly and adds additional burden. The burden not only financial, it is mainly technical and managerial. Producing renewable energy and maintaining freshwater resource, reducing electricity production and emissions depend also on R &amp; D practices such as trademark and patent applications. This also needs engineers, technicians, scientists and human capabilities with continuous knowledge and intellectual capital. The main research hypothesis has tested the effect of environmental protection and compliance on the R&amp;D in intellectual capital creation. Environmental reactions are measured by &ldquo;renewable internal freshwater resources&rdquo;, &ldquo;electricity production from renewable sources&rdquo;, &ldquo;access to electricity&rdquo; and &ldquo;alternative and nuclear energy&rdquo;, while R &amp; D practices are measured by &ldquo;trademark applications&rdquo;, &ldquo;technicians in R&amp;D&rdquo; and &ldquo;patent applications&rdquo;.
Research hypotheses has been tested using panel regression analysis according to GMM technique. Using data of 94 countries during the period from 2001 to 2019, findings show that there are significant effect of &ldquo;trademark applications&rdquo; on &ldquo;renewable internal freshwater resources&rdquo; and of &ldquo;technicians in R&amp;D&rdquo; on each of &ldquo;electricity production from renewable sources&rdquo; &ldquo;access to electricity&rdquo; and &ldquo;alternative and nuclear energy&rdquo;. Besides, &ldquo;patent applications&rdquo; seems to have significant effect on &ldquo;alternative and nuclear energy&rdquo;. Results have found that countries that have made environmental improvements are those who have invested in intellectual capital and made significant steps in improving their environmental R&amp;D Capabilities.
Studi Deskriptif Pembelajaran Daring Pada Mata Pelajaran IPA Terhadap Siswa SMP Bhakti Mulia Wonosobo
Authors: Indraswari Rosita 
Published: March 2022

This study aims to identify the factors that influence the success of online learning and evaluate the implementation of online learning that has been in progress. The research method was carried out by distributing questionnaires to 34 students which were saturated samples where all students became respondents as well as primary sources. The data were analyzed descriptively to explain the existing phenomena. The results showed that online learning had been carried out well with satisfactory learning outcomes due to the influence of factors such as adequate media equipment, student learning motivation, teacher ability in teaching, mastery of teaching materials. and proficiency in using online devices as media, as well as students' level of understanding.
Reseña: F. J. Gómez Espelosín, En busca de Alejandro: historia de una obsesión, Alcalá de Henares, Servicio de publicaciones de la UAH, 2016, 438pp. [ISBN 978-84-16599-88-2].
Authors: Molina Ignacio 
Published: March 2022

Reseña de F. J. Gómez Espelosín, En busca de Alejandro: historia de una obsesión, Alcalá de Henares, Servicio de publicaciones de la UAH, 2016, 438pp. [ISBN 978-84-16599-88-2].