bluuebunny/crossref_metadata_2025_split huggingface dataset:
СИСТЕМА ПАРОСНАБЖЕНИЯ НЕФТЕПЕРЕРАБАТЫВАЮЩЕГО ПРЕДПРИЯТИЯ КАК ОБЪЕКТ УПРАВЛЕНИЯ
Authors: Матвейкин Валерий Григорьевич , Краснянский Михаил Николаевич , Дмитриевский Борис Сергеевич , Василевский Константин Сергеевич 
Published: September 2022

Актуальность исследования обусловлена необходимостью разработки и внедрения комплекса программно-технических средств – системы автоматизированного управления процессом пароснабжения – для осуществления оптимального управления энергетическими ресурсами – паром среднего и высокого давления. В настоящий момент система управления данным ресурсом представляет собой разрозненные локальные системы автоматизированного регулирования с обратной связью, осуществляющие стабилизацию параметров теплоносителя в момент подачи на установку. Исследование в данном направлении позволит сформировать централизованный подход к управлению технологическим процессом пароснабжения и улучшить технико-экономические показатели нефтеперерабатывающих производств.Цель: разработка такой автоматизированной системы управления процессом пароснабжения, которая бы сократила потребление пара внешней выработки и максимально использовала внутренние ресурсы предприятия. В рамках реализации данной системы предполагается, что разрабатываемая автоматизированная система управления направлена на повышение энергоэффективности паропотребляющих производств.Объект: система пароснабжения нефтеперерабатывающего предприятия, состоящая из последовательно и параллельно соединенных трубопроводами установок-потребителей и установок-генераторов пара среднего и высокого давления.Методы исследования основаны на формировании математического описания установок, участвующих в технологическом процессе пароснабжения, вычислительной математики, теоретических основ автоматического управления, а также современных подходов в управлении технологическим процессом.Результаты. Осуществлена декомпозиция технологического процесса пароснабжения в разрезе отдельных установок. Каждый элемент был рассмотрен как объект управления, для каждого из объектов управления определены векторы входных, выходных, промежуточных величин и возмущающего воздействия. На основе полученных данных предложен алгоритм управления процессом пароснабжения, определена структура системы управления и подобраны основные элементы комплекса программно-технических средств.
ПРОСТАЯ МЕТОДОЛОГИЯ ДЛЯ ДОЛГОСРОЧНОГО ПРОГНОЗИРОВАНИЯ КАЧЕСТВА ЗЕРНА
Authors: Кирста Юрий Богданович , Пузанов Александр Васильевич , Рождественская Тамара Анатольевна 
Published: September 2022

Цель: разработка универсальной интегрированной методологии и статистико-имитационной модели для долгосрочного прогноза содержания токсичных химических элементов в урожаях зерновых культур. Объекты. Исследование основано на системном подходе и проведено на примере пшеницы, выращиваемой в Алтайском крае – одном из основных зернопроизводящих регионов России. Образцы пшеницы были отобраны в 10 районах, несколько различающихся по климатическим условиям. Всего было изучено содержание 19 химических элементов (Pb, Cd, Co, Cr, Cu, Hg, Ni, Zn, Al, As, Ba, Ca, Fe, K, Mg, Mn, Mo, Na, P). Показано, что концентрации Pb (свинец), Cr (хром), Cu (медь) и Na (натрий) в зерне пшеницы зависят от климатических особенностей района возделывания. Методы. Установлены регрессионные зависимости содержания элементов от среднемноголетних месячных значений температуры воздуха и осадков. На основе регионального векового климатического цикла, нормализации и пространственного обобщения температуры воздуха и осадков, обеспечивающих единообразную динамику их относительных месячных значений (в процентах) по всему исследуемому региону, был составлен прогноз их изменений к 2030 г. Результаты. Процедура отбора проб зерна, ГИС-технологии для обработки метеорологических и картографических данных, методы прогнозирования изменений климата и определения количественных взаимосвязей содержания химических элементов в зерне с климатическими характеристиками – все вместе составляют методологию, позволившую разработать прогностическую модель содержания токсичных веществ в пшенице. Модель использована для оценки изменений Pb, Cr, Cu и Na в зерне пшеницы к 2030 г. Содержание других элементов в пшенице слабо коррелирует с многолетними изменениями температуры воздуха и осадков, поэтому оно вряд ли может существенно измениться. После 2030 г. концентрации Pb, Co (кобальт) и Cr в пшенице, поставляемой на элеваторы из некоторых муниципальных районов, превысят их допустимые уровни для продовольственного зерна.
РОЛЬ ОПАСНЫХ ГЕОЛОГИЧЕСКИХ ПРОЦЕССОВ ПРИ ЭКСПЛУАТАЦИИ НЕФТЕПРОВОДА «ЧАЯНДА-ВСТО»
Authors: Строкова Людмила Александровна , Нечаев Дмитрий Андреевич 
Published: September 2022

Актуальность работы определена важностью обеспечения бесперебойной работы трубопроводного транспорта, обусловливающего энергетическую и экономическую безопасность страны. Проявления опасных геологических процессов могут привести к сбоям в работе трубопроводов с последствиями, варьирующимися от травм/смерти, воздействия на окружающую среду и материального ущерба до длительных перебоев в обслуживании и невыполнения поставленных задач. Отказы в работе трубопроводов в результате природных явлений, как правило, являются редкими (но дорогостоящими) событиями. Именно поэтому важно правильно оценить грунтовые условия и предсказать их изменение при эксплуатации трубопровода.Цель: идентифицировать участки трассы с вероятной активацией опасных геологических процессов и их влияние на эксплуатацию сооружения.Методы: анализ результатов инженерных изысканий по обустройству Чаяндинского нефтегазоконденсатного месторождения и данных геотехнического мониторинга по трассе нефтепровода.Результаты. Проведено описание инженерно-геологических условий трассы нефтепровода. Наиболее распространенными опасными геологическими процессами в пределах трассы трубопровода являются карст, заболачивание, водная эрозия, а также проявления геокриологических процессов – термоэрозия, термокарст, морозное пучение, морозное трещинообразование, наледеобразование. Определены участки проявления геологических процессов по трассе трубопровода. Наиболее протяженными оказались процессы, связанные с изменением многолетнемерзлых грунтов и карстовые процессы. Оценка вклада опасных геологических процессов произведена по секциям между узлами запорной арматуры нефтепровода, что позволит обеспечить безопасность транспортировки нефти, ее регулировку за счет отключения участка линейной части трубопровода. Идентифицированы наиболее уязвимые участки трассы нефтепровода по возможности проявления геологических опасностей.
Résidus d’antibiotiques dans la viande bovine et les œufs vendus à N’Djaména et à Moundou (Tchad)
Authors: Amine Alhadj Souleymane , Soudy Imar Djibrine , Zoli Pagnah André , Mouiche Mouliom Mohamed Moctar , Bagari Iya Souley 
Published: September 2022

Ces dernières décennies, l’intensification de la production animale a été favorisée par l’usage des médicaments vétérinaires, en particulier les antibiotiques. Dans ce contexte, cette étude a été menée afin de rechercher la présence de résidus d’antibiotiques dans les denrées alimentaires d’origine animale comme la viande de bovins et les œufs de poules. Des échantillons ont étés prélevés (166 issus de viande bovine et 227 d’œufs) dans différents points d’abattage et de commerce des villes de N’Djaména et Moundou au Tchad. Les résultats ont montré la présence de résidus d’antibiotiques dans 72 des 166 échantillons de viande, soit une prévalence de 43,3 %, et dans 60 des 227 échantillons d’œufs, soit une prévalence de 26,4 %. Ces pourcentages élevés de résidus d’antibiotiques dans les denrées alimentaires fréquemment consommées constituent un problème de santé publique. Des études avec des méthodes quantitatives plus poussées devraient être conduites pour identifier la nature des antibiotiques présents dans ces denrées, ainsi que pour en quantifier les teneurs.
Effects of financial statement and macroeconomic factors on risk measures of banks in India
Authors: Banerjee Gaurango , Gupta Abhimanyu , Das Abhiman 
Published: September 2022

This paper aims to analyse the effects of financial statement indicators and off-balance sheet items affecting risk measures among Indian banks employing both panel data regression and a non-parametric decision tree approach. We explore the effects of bank size, leverage, exposure to contingent liabilities including off-balance sheet derivatives usage and macroeconomic factors on risk measures for banks. In this paper, it is also aimed to examine the effects of the major financial liberalization policy period in the domestic market in India that started in the mid-1990s and ended around 2004 as well as impacts of the 2008 global financial crisis on the risk measures of banks operating in India. As risk measures, we present a comparative analysis of liquidity, solvency, and interest rate risk measures of Indian banks across public (government) and private ownership categories. Main findings from our study demonstrate (i) significant impact of capital adequacy and the bank size on all the risk measures, (ii) contingent liabilities (including derivatives usage) at banks is observed to significantly impact the asset management measure of liquidity risk and the solvency risk of banks, (iii) GDP growth is observed to impact the asset management and liability management measure of liquidity risk, (iv) the global financial crisis is found to have a significant impact on the liquidity risk measures and interest rate risk, but a weak effect on solvency risk of Indian banks, (v) bank ownership category (government owned versus private sector banks) is observed to have a significant impact on all the risk measures, and finally (vi) financial liberalization reforms had a highly significant effect on the liquidity risk at banks.
Health Remedies as a Source of Lead, Mercury, and Arsenic Exposure, New York City, 2010–2019
Authors: Hore Paromita , Alex-Oni Kolapo , Sedlar Slavenka , Patel Kari , Saper Robert B. 
Published: September 2022

Objectives. To describe the types of health remedies collected during poisoning investigations in New York City over a 10-year period that were found to contain high levels of lead, mercury, or arsenic. Methods. Between 2010 and 2019, the New York City Department of Health and Mental Hygiene collected 584 samples of health remedies during poisoning investigations and store surveys for lead, mercury, or arsenic analysis. Results. There was a significant association between blood lead levels and estimated cumulative daily lead exposures among adult users of rasa shastra Ayurvedic medications. Also, average blood lead levels among adult rasa shastra users were significantly higher than levels among those using other types of non-Ayurvedic health remedies. Conclusions. Rasa shastra Ayurvedic medications can contain very high levels of lead, mercury, and arsenic. This underscores the importance of screening for lead, mercury, and arsenic exposures within at-risk populations. Public Health Implications. The general ease of accessibility to rasa shastra medications raises concerns. There is a need for systemic change that results in primary prevention, that is, removal of the source through policy development and regulatory enforcement in the country of origin. (Am J Public Health. 2022;112(S7):S730–S740. https://doi.org/10.2105/AJPH.2022.306906 )
Exposure Sources Among Veterans With Elevated Blood Lead Levels, United States, 2015‒2021
Authors: Oda Gina , Sharma Aditya , Lucero-Obusan Cynthia , Schirmer Patricia , Holodniy Mark 
Published: September 2022

Objectives. To determine characteristics and sources of exposure in veterans with elevated blood lead levels (BLLs). Methods. We included users of US Veterans Health Administration care aged 18 years or older tested for BLL from October 2015 to September 2021. Prevalence of BLL 10 micrograms per deciliter (µg/dL) or higher and 25 µg/dL or higher was determined within demographic groups. Logistic regression analysis measured association of International Classification of Diseases, Tenth Revision, Clinical Modification‒coded conditions with elevated BLL. Electronic notes were reviewed for exposure sources. Results. Among 1007 unique veterans with BLL 10 µg/dL or higher, prevalence of BLL 10 µg/dL or higher and 25 µg/dL or higher peaked at 4.9 and 1.3 per 100 000 veterans, respectively (fiscal year 2019), and was highest in non-Hispanic White men and those aged 25 to 34 years. Conditions predicted by elevated BLL were attention-deficit/hyperactivity disorder (ADHD) and nausea or vomiting. Firearms represented 70.1% of occupational and 85.9% of nonoccupational exposures. Toxicology consults occurred in 17 of 298 (6%) with BLL 25 µg/dL or higher. Conclusions. Firearms were the largest exposure source among veterans with elevated BLL. Clinicians should be alert for potential conditions (including ADHD and nausea or vomiting in our study) associated with lead exposure. Standardization of care regarding toxicology referral practices is warranted. (Am J Public Health. 2022;112(S7):S670–S678. https://doi.org/10.2105/AJPH.2022.306936 )
Drivers, barriers, and response to care of Australian pregnant women seeking chiropractic care for low back and pelvic girdle pain: A qualitative case study
Authors: Bernard-Giglio Maria , French Simon D , Myburgh Corrie , de Luca Katie 
Published: September 2022

AbstractBackground Pregnancy-related low back and/or pelvic girdle pain is common, with a prevalence of pelvic girdle pain at 44% in Australian women. Although 20% of Australian pregnant women visit a chiropractor for pelvic girdle pain, little is known about the experience of pregnant women who seek this care.The aim of this study was to explore and describe the lived experiences of Australian pregnant women who seek chiropractic care for their current pregnancy-related low back and/or pelvic girdle pain. Methods A qualitative case study approach with purposive sampling, from 27 chiropractic practices, was used. A constructivist and interpretivist stance provided understanding and meaning to the pregnant women’s lived experiences. Unstructured interviews using an audio-visual recording on an online platform were performed. A thematic analysis, based on a framework of transcribed interviews, memos, survey findings with triangulation and respondent validation was undertaken. Results 16 potential participants expressed interest in participating. After eligibility screening, nine interviews were undertaken. The thematic analysis identified four key themes: care drivers, care barriers, chiropractic treatment, and response to care. Conclusion Four key themes were identified, which support an overarching substantive-level theory that chiropractic care for pregnant woman experiencing low back pain and/or pelvic girdle pain improves pain and function, while reducing pregnancy-related biopsychosocial concerns. Due to the qualitative study design, findings have only “naturalistic” generalisability and general transferability. However, the findings may inform antenatal providers and the chiropractic profession about pregnant women’s experience with chiropractic care as well as directing future research. Ethics Approval: The research was granted ethics approval with Macquarie University Human Research Ethics applications # 52020621817665.
Kv1.3 in Microglia Cell Mediates Neurological Dysfunction after Traumatic Brain Injury
Authors: Chen Xingxing , Ge Yiqin , Zhang Die , Jiang Haopeng , Wan Wenyan , Yuan Yi , Tang Lele 
Published: September 2022

Abstract
Background
Traumatic brain injury (TBI) is a kind of brain structure destruction and brain dysfunction syndrome caused by mechanical injury. At present, the treatment of traumatic brain injury is mainly neuroprotective drugs, but the efficacy is limited. Therefore, the exploration of effective therapeutic targets for traumatic brain injury has become a key scientific problem in current neuropharmacological research. Studies have found that neuroinflammation is closely related to the occurrence and development of traumatic brain injury. After activation of central microglia cell, various cellular inflammatory factors will be secreted, causing damage to the central nervous system and causing neuroinflammation. Studies have shown that potassium channel Kv1.3 plays a crucial role in microglia-mediated neuroinflammation, but the mechanism of microglial potassium channel Kv1.3 on traumatic brain injury remains unclear.
Methods
In this study, the functional localization of potassium channel Kv1.3 in microglia cell was investigated by behavioral observation, patch clamp, immunofluorescence, Western blotting, real-time PCR and other techniques in mice model of repetitive traumatic brain injury combined with Kv1.3 gene knockout mice.
Results
We found significant neurological deterioration in TBI mice, and knockdown of Kv1.3 effectively reversed TBI-mediated neurological dysfunction. The expression of inflammatory factors IL-1β and TNF-α was significantly increased in the hippocampus of mice with traumatic brain injury, and the down-regulation of Kv1.3 gene significantly inhibited the expression of these inflammatory factors.
Conclusion
Potassium channel Kv1.3 in microglia cell is an important regulatory target in repetitive traumatic brain injury.
Long-acting injectable in situ gel of rasagiline: a patented product development
Authors: Zhao Dongyang , Chen Ping , Hao Yuanbin , Dong Jing , Dai Yu , Lu Qingqing , Zhang Xin , Liu Chia-Wen 
Published: September 2022

Abstract
Rasagiline has certain potential in neuroprotection and delaying the progression of Parkinson's disease (PD). However, the poor pharmacokinetics (PK) characteristics of conventional oral tablets and poor medication compliance limit the optimal efficacy of rasagiline. Based on this, we designed and optimized a sustained-release rasagiline in situ gel based on in vitro release and in vivo PK results. Among them, we found for the first time that aluminum hydroxide can effectively shorten the lag phase and promote the early and late release, making the daily release more uniform. After subcutaneous administration of the optimized gel formulation at a monthly dose, the Cmax (64 ng/ml) was lower than that of free rasagiline (494 ng/ml) administered subcutaneously at a daily dose and comparable to that of oral administration of Azilect® (59.1 ng/ml) at a daily dose. Meantime, the plasma concentration of rasagiline was mainly maintained at 5-10 ng/ml for about one month, and the active metabolite 1-aminoindane in plasma was also able to maintain a steady state. The rasagiline in situ gel has suitable viscosity and injectability, good repeatability of subcutaneous injection, controllable impurities, and can achieve sustained release in vivo with small burst release, which may have the clinical application advantages of maximizing the disease-modifying effect of rasagiline and improving medication compliance.
Association of Socio-demographic Characteristics with Hypertension Awareness, Treatment, and Control in Bangladesh
Authors: Babagoli Masih , Chen Yea-Hung , Chakma Nantu , Islam Md. Saimul , Naheed Aliya , Boettiger David 
Published: September 2022

Abstract

The prevalence of hypertension has been rapidly growing in Bangladesh. Despite this burden, there has been limited analysis of the socio-demographic variation of each step of the hypertension cascade of care. This study was a secondary analysis of the 2017-18 Bangladesh Demographic and Health Survey. Four dichotomous outcome variables – hypertension prevalence, awareness among those with hypertension, treatment among those aware, and control among those treated – were analyzed. The variation of each outcome was assessed across socio-demographic factors; the association between socio-demographic characteristics and the four outcomes was analyzed using logistic regression. In Bangladesh, 27.5% [95% CI 26.5, 28.5%] of individuals had hypertension, 42.5% [95% CI 40.5%, 44.5%] of those with hypertension were aware, 87.4% [95% CI 85.3%, 89.5%] of those aware were receiving treatment, and 33.8% [95% CI 30.8%, 36.8%] of those receiving treatment had their blood pressure controlled. Hypertension prevalence and awareness were higher among older individuals, females, and those with higher household wealth. Comparing older to younger individuals, the proportion of treatment among those aware was higher, while control among those treated was lower. In multivariable models stratified by rural/urban community, the impact of education on odds of treatment differed between rural and urban communities. Specific efforts to improve hypertension awareness among individuals who are younger, male, of lower household wealth, and in rural areas are required to address disparities in hypertension care. Socio-demographic variations in hypertension awareness, treatment, and control must be considered to design targeted interventions for each step of the cascade.
Predicting hospital admissions and its cost due to respiratory diseases in Brazil using Machine Learning Time Series Forecasting
Authors: Ferreira Rafaela , Goularte Vinicius , Pate Arthur , Braga Marion Coting , AbreuB Ariane , Pereira Ramon Gonçalves 
Published: September 2022

Abstract

Background: Respiratory diseases (RD) impose an immense health burden and over 1 billion people suffer from acute or chronic RD. Artificial Intelligence (AI) can improve the quality of healthcare, with the potential of assisting in the medical diagnosis of many diseases and reducing unnecessary hospitalizations and costs. This article aims to develop a Machine Learning (ML) model to predict the healthcare resources utilization (HCRU) and costs associated to RD hospitalizations in the Brazilian public health system (SUS).
Methods: Data were extracted from three public databases: Hospital Information System (SIH), “e-saúde” database and Meteorological Database, in the city of Curitiba, between 2017 and 2019. All analyzes considered the number of hospitalizations per day. The outcomes predicted by ML were the cost and the number of hospitalizations in the next seven days after a RD claim. The models were created by data mining process. Different algorithms were tested by the model building process up to five times. The best model for the seven-day cost and utilization forecasts was defined according to mean absolute percentage error (MAPE), mean absolute error (MAE), root mean squared error (RMSE). The SHAP method was used to analyze the interpretability of the best selected model.
Results: There were, on average, 315.41 hospitalizations and 97,596 primary care services for RD per week in the city of Curitiba between 2017 and 2019, with an average cost of 246,390.30 US dollars (R$ 549,332.87). The Recurrent Neural Network (RNN) methods (LSTM and GRU) presented the best results for forecasting costs and HCRU. LSTM model outperformed all other algorithms in both models with a RMSE of 0.07 and 0.04 respectively. The most impacting variables in the model (SHAP analysis) were the meteorological ones. However, the forward to specialist, type of attendance and medical specialty on the ambulatorial records were also important. High average temperatures support the model to make a prediction of a smaller number of hospitalization days for that period.
Conclusion: The prediction model used was robust enough to predict information about hospitalization and costs related to RD, demonstration its applicability as a tool to optimize resources allocation and health promotion strategies.