bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using Simplified Linear and Nonlinear Models to Assess ENSO-Modulated MJO Teleconnections
Authors: Arcodia Marybeth C. , Kirtman Ben P. 
Published: July 2022

Abstract
Some simple dynamical models have proven to be useful tools for understanding tropical-extratropical teleconnections. Here, we use simple linear and non-linear dynamical models to understand how ENSO modulates subseasonal teleconnections associated with the tropical imprint of the MJO. Both a dry linear baroclinic model (LBM) and a dry nonlinear baroclinic model (AGCM) are employed to 1) assess how much of the MJO teleconnection pattern in a particular ENSO phase can be captured by linear and nonlinear dynamics and 2) understand the key driver(s) in differences in Northern Hemisphere MJO teleconnection patterns based on ENSO phase. The modeling experiments reveal that elements of the Northern Hemisphere teleconnection pattern are a direct Rossby wave response to tropical MJO heating. Nonlinear dynamics modestly capture more of the Northern Hemisphere MJO teleconnection pattern than linear dynamics alone, but some key elements of the teleconnection pattern seen in Reanalysis are still missing in the model representations. Both models show that the response is sensitive to the location and domain of the MJO-associated forcing and the month, MJO phase, and ENSO phase of the forcing and background state. Further, ENSO modulates both the spatial structure and magnitude of the MJO teleconnections and results show that the ENSO-modulated MJO forcing is the dominant driver of the mid-latitude response over the background state. The results show evidence for subseasonal variability related to the MJO within the interannual ENSO teleconnections in the North Pacific and North America and so MJO teleconnections must be considered in the context of the ongoing ENSO event
Protective effect of Alisol A on cerebral ischemia-reperfusion induced neurovascular unit dysfunction by activating AKT/GSK3β pathway in vivo
Authors: Li Huihong , Wei Wei , Zhan Zengtu , Lu Taotao , Lin Libin , Li Yongxu , Zhou Yangjie , Yang Jingda , Deng Yunfei , Zheng Xiaoqing , Ding Linlin , Xu Peitao , Xue Xiehua 
Published: July 2022

Abstract
Background:
Neurovascular unit (NVU) dysfunction is a major process in the pathophysiological process of cerebral ischemia-reperfusion (CI/R). Our previous studies have confirmed that the main active ingredient of Alisma orientale exhibits protective effect on CI/R injury. Therefore, this study is designed to verify whether Alisol A, one of the main active components of Alisma, attenuates CI/R-induced NVU dysfunction through activation of AKT/GSK3β pathway.
Methods
C57BL/6J mice were used to establish the animal model of global cerebral ischemia- reperfusion (GCI/R) and treated with Alisol A and GSK690693 (an AKT inhibitor). We carried out modified neurological severity score (mNSS) and morris water maze (MWM) to test learning and memory abilities. Nissl staining and CD31, GFAP, Iba1, NeuN immunostaining were performed to determine morphological and quantitative changes in neuronal and endothelial cells, as well as overactivation of astrocytes and microglia. Ultrastructure changes of NVU were observed by transmission electron microscope (TEM). Expression of IL-6, IL-1β, BAX, Bcl-2 and AKT/GSK3βwere detected by enzyme-linked immunosorbent assay (ELISA) and western blot. The alterations in neuronal/glial metabolism were measured using magnetic resonance spectroscopy (MRS).
Results
The data showed that Alisol A treatment significantly improved neurological deficits and memory loss caused by GCI/R in C57BL/6J mice. Furthermore, Alisol A administration effectively suppressed the disruption of neurons and endothelial cells, activation of astrocytes and microglia, cell apoptosis and release of inflammatory factors in GCI/R-induced C57BL/6J mice, which were reversed by GSK690693.
Conclusions
Alisol A significantly alleviated NVU damage caused by GCI/R via activation of AKT/GSK3β, suggesting that Alisol A maybe a promising medicine for the treatment of GCI/R.
Strong Double Space-Time Wave Packets from Optical Parametric Amplification
Authors: Li Zhaoyang , Leng Yuxin , Li Ruxin 
Published: July 2022

Abstract
The space-time (ST) wave packet, a new type light source with many new features, has already found applications in weak-field optics, however its generation method limits its energy and therefore its application in strong-field optics. We report that the type-I collinear optical parametric amplification (OPA) is a natural amplifier for ST wave packets, because in it, the ST spectrum (i.e., angle-dependent phase-matching spectrum) of the signal and idler has the same analytical expression as that of ST wave packets under the narrowband approximation. The high gain in a thin-crystal OPA allows for large energy amplification while ensuring unchanged ST correlation. Meanwhile, for the first time, a double ST wave packet containing two collinear-propagating ones of the amplified signal and the generated idler via the nondegenerate OPA is reported, which with short- and long-wavelengths (relative to the degenerate-wavelength) have superluminal and subluminal velocities, respectively. This study realizes energy amplification, wavelength conversion, and velocity switching of ST wave packets and will certainly expand the application in many fields.
On-farm Diversity, Use Pattern and Conservation of Enset (Ensete ventricosum) Genetic Resources in Southern Ethiopia
Authors: Dilebo Tesfaye , Feyissa Tileye , Asfaw Zemede , Zewdu Ashagire 
Published: July 2022

Abstract
Background: Enset is an important source of food for millions and consumed as a staple or co-staple food crop mainly in southern parts of the Ethiopia. Large numbers of enset landraces exist in different administrative zones of Ethiopia with a wide range of altitude. However, limited information is available on the diversity, their distribution and utilization pattern comparatively to the diverse ethno-linguistic as well as socio-cultural communities of the country. Hence, this study was devised to explore and document richness of farmers’ tradition and practice on diversity and distribution of enset landraces on farm-level and selection pattern for different purposes in regarding to its production, utilization and conservation of enset genetic resources.Methods: The study was conducted in four major enset growing administrative zones of Ethiopia namely, Hadiya, Kembata-Tembaro, Gurage and Silte. A total of 240 farm households were surveyed using individual interviews, key informants interviews, focus group discussions and direct on-farm field observations.Results: A total of 282 farmer-named landraces have been identified, with a range from 2 to 32 on individual homegarden. The largest numbers of landraces was found in the Hadiya Zone (86); while the lowest was scored in the Silte Zone (57). The Shannon diversity index (H') ranged from 3.73 (Silte) to 3.96 (Hadiya). Similarly, landraces revealed a very narrow range of variances in the Simpson’s 1-D diversity index, and it ranged from 0.963 (Silte) to 0.978 (Hadiya). Likewise, the similarity index ranged from 0.24 to 0.73 sharing 16-47 landraces in common. Of the 282 landraces, 210 (74.5%) were recorded in more than one zones; whereas, 72 (25.5%) had a narrow distribution and were restricted to single zone. Conclusions: Farmers have established long term practices and experiences in cultivation, utilization and conservation of a diverse group of enset landraces to fill their domestic purposes in each zone. Therefore, in order to facilitate on-farm conservation as well as sustainable utilization of the enset genetic resources, farmers need to be supported by different stakeholders for all their worth, and also in improvement programs. In addition to this, to clarify the exact nature of synonyms and to see if they are duplicates molecular analysis would be helpful and recommended as a follow-up work.
Gas-phase fragmentation of single atom incorporated Co5MS8(PEt3)6+ (M=Mn, Fe, Co, Ni) nanoclusters
Authors: Ranjbar Habib , Deepika - , Jena Puru , Laskin Julia 
Published: July 2022

Abstract
Functionalization of metal-chalcogenide clusters by either replacing one or more of the core metal atoms or by choosing the ligand is a powerful technique to tailor their properties and synthesize cluster assembled materials. Central to this approach is to understand the competition between the strength of the metal-ligand and metal-metal interactions within the cluster. We use collision-induced dissociation (CID) of two series of atomically precise metal sulfide nanoclusters including Co5MS8L6+ (L=PEt3, M= Mn, Fe, Co, Ni) and Co5-xFexS8L6+ (x=1-3) to understand the effect of a heteroatom incorporation on the core-ligand interactions and relative stability towards fragmentation. We observe sequential ligand loss as the dominant dissociation pathway for all the clusters, which occurs in competition with the loss of ligand sulfide (LS). Because all the ligands are attached to metal atoms in the precursor cluster cations, LS loss is an unusual dissociation pathway, indicative of a rearrangement of the cluster prior to fragmentation. Collision energy-resolved CID combined with theoretical calculations reveals the reduced stability of Co5MnS8L6+ and Co5FeS8L6+ cations towards the loss of the first ligand in comparison with their Co6S8L6+ and Co5NiS8L6+ counterparts. Moreover, we observe that the relative stability of clusters towards ligand loss as well as the competition between ligand and LS losses are strongly dependent on the composition of the clusters. Theoretical studies also confirm that the first ligand always prefers to detach from the doped-metal atom site to form Co5MS8L5+ cations. This study provides new insight into modulation of the core-ligand interaction of the atomically precise metal chalcogenide clusters suggesting paths to generate reactive species to promote inter-cluster reactions.
Comparing the BDA Case Mix Tool and Simplified Case Mix Tool for stratification of public dental patients with disability in South Australia
Authors: Lin Trudy , Liberali Sharon , Gryst Mark , Edwards Suzanne 
Published: July 2022

Abstract
Introduction: All individuals have a right to equal access to oral healthcare. Finding a dental practitioner experienced in managing individuals with special needs, is a commonly reported barrier to accessing oral healthcare for people with disabilities.Aim:The aim of this study was to determine the applicability of the British Dental Association Case Mix Tool and the simplified Case Mix Tool for the Australian context.Methods: A retrospective analysis of 131 dental records for patients on recall at the Special Needs Unit, Adelaide Dental Hospital compared the specialist-performed complexity stratification with results obtained using the British Dental Association case mix tool and simplified case mix tool by a general dentist.Results: The British Dental Association case mix tool demonstrated substantial agreement with the specialist-performed complexity stratification and had a higher reliability than the simplified case mix tool.Conclusions: The British Dental Association case mix tool may be suitable for use in the Australian context by general dental practitioners, to identify the level of complexity of an individual with special needs, so as to ensure their oral healthcare needs are matched to a dental practitioner with the required skills and experience.
The use of remote sensing data that is studying the environmental consequences of the Russian invasion of Ukraine
Authors: Serhii Shevchuk , Viktor Vyshnevskyi , Bilous Olena 
Published: July 2022

Abstract
The ongoing events of the Russian invasion of Ukraine seriously impacted on the environment in all areas: ground, air, water, flora and fauna. First of all, this war has created a massive increase in air pollution. The Russian attack has caused many fires at oil depots, industrial complexes, equipment and ammunition stockpiles, the forests, residential areas, etc. In addition to this, many bridges, hydraulic and other structures destroyed that seriously affected water bodies such as rivers and lakes which were seriously polluted. These events were studied by using publicly available remote sensing data, as well as from the media. Much attention is paid to the data provided by NOAA-2, Suomi NPP, Aqua and Terra satellites. In addition, the research used data from Sentinel and Landsat satellites, which are making it better to visualizate the consequences of the Russian military invasion.
Inadequacy of treating turbidity currents as river analogues and implications for autosuspension criterion
Authors: Fukuda Sojiro , de Vet Marijke , Skevington Edward , Bastianon Elena , Fernández Roberto , Wu Xuxu , McCaffrey William , Naruse Hajime , Parsons Daniel , Dorrell Robert 
Published: July 2022

Abstract
“Consider the [turbidity] current as that of a river” R. A. Bagnold (1962);the foundation of contemporary deep marine sedimentology.Submarine sediment-laden buoyancy-driven flows, or turbidity currents, are critical as key vectors for material, nutrient, and pollutant dispersal in the world’s oceans. Extant models of turbidity currents assume that material transport is dynamically similar to open-channel flows. Here, 70 years of empirical research is integrated with new data, to show that material transport by turbidity currents is fundamentally different from fluvial systems. Although central to previous work, turbidity currents do not follow classic flow-power models for material transport; and are not “rivers on the seafloor” as previously postulated. Contrary to current theory, work done keeping sediment in suspension is shown to have a strongly non-linear dependence on available flow power. The observed relationship is attributed to an underestimation of turbulent kinetic energy (TKE) production. The energy budget has direct implications for the enigmatic autosuspension processes and ultra-long runout of turbidity currents, thus these insights are crucial for the understanding of these flows. The accurate prediction of autosuspension and runout is essential to the understanding of deep marine biogeochemical cycling and anthropogenic environmental impact.
Characterization, axial anisotropy and formation conditions of celestine minerals from the Jabal Eghei (Nuqay) volcanic province (southeastern edge of the Sirt Basin, southern Libya)
Authors: Tančić Pavle , Milošević Maja , Spahić Darko , Kostić Bojan , Kremenović Aleksandar , Poznanović-Spahić Maja , Kovačević Jovan 
Published: July 2022

Abstract
Five celestine crystals, sampled from the surface at the Miocene to Pliocene Jabal Eghei (Nuqay) volcanic province (southern Libya), are characterized by applying the combination of the SEM-WDS, XRPD and IR methods; and analyzed for their color variations and minerogenesis. Three samples have greenish-blue to blue (480.4−482.5 nm), whereas the other two samples are of blue-green color (cyan; 489.1−494.1 nm). The color purity is in the 1.36–7.16 range. Their chemical composition is mutually similar, fitting into the celestine near-end members, in which exclusively 1.6–4.1 at. % of Sr2 + contents was substituted by Pb2+ (0.7–0.9 at. %), Ba2+ (0.5–0.7 at. %) and Ca2+ (0.2–0.8 at. %); including the vacancies (1.0−1.9 at. %; only in three samples). The resulting unit-cell parameters have the following ranges: a0 = 8.3578(9)−8.3705(6) Å; b0 = 5.3510(5)−5.3568(4) Å; c0 = 6.8683(7)−6.8767(2) Å and V0 = 307.17(5)−308.34(4) Å3. The XRPD and IR results are mainly in accordance with the SEM-WDS analyses, having higher mutual correlativity. However, a few discrepancies among the results are observed, further yielding several possible interpretations. The overall results show that discrepancies were primarily induced by a slight unit-cell axial anisotropy, occurring as a consequence of their thermal expansion. Essentially, the investigated Sr-bearing celestines were formed as a secondary volcanic system, emplaced over the gypsum and/or anhydrite minerals, at ~ 368−430K (~ 95–157 oC) temperature range, in the ambient pressure conditions. The study further shows that the investigated celestine minerals are likely formed at a slightly elevated temperature and pressure subsurface environment, reaching over 250 bars.
Application of Pareto optimality-based adaptive PSO to solve multicast type routing issues with multiple objectives
Authors: Gopalan Harihara , Elngar Ahmed A. 
Published: July 2022

Abstract
In network communication and distributed systems, numerous applications transmit data from the source to several destinations. The multicast routing is a remarkable combinatorial optimization issue with multiple objectives to optimize. Hybrid multi-objective evolutionary algorithms are employed for multicast routing. In this study, Pareto optimality-based adaptive PSO with variants are projected. The proposed algorithm and its variants optimize the cost, delay, and lifetime of the multicast tree. The aim is to construct a multicast type tree for transmitting data to minimize the cost, delay, and lifetime. Various strategies such as multi-objective weighted sum, dynamic inertia weight, adaptive non-dominated sorting approaches, and multi-objective local search based on the Pareto hill-climbing approach are implemented to identify the shortest path. The results are analyzed with respect to the cost, delay, and lifetime. The results of the ANS_MOPSO_PHC algorithm overtake the other techniques in this study.
Elevated serum Krebs von den Lungen-6 in primary Sjögren syndrome: a marker of lung fibrosis and severity of the disease
Authors: Wu Xue , Wu LiJun , Su JinMei , Luo Cainan , Meng XinYan , Chen Yi , Lei Xin 
Published: July 2022

Abstract
Background: To assess the diagnosis significance of the serum Krebs von den Lungen-6 (KL-6) for the interstitial lung disease (ILD) related to primary Sjögren syndrome(pSS-ILD) Methods: An overall 79 pSS-ILD sufferers and 71 pSS sufferers from our hospital between Jan 2015 and May 2021 were enrolled. The measuring of serum KL-6, lung function testing, and high-resolution computed tomography (HRCT) completed simultaneously were studied. Serum KL-6 concentrations were measured with chemiluminescent enzyme immunoassay (CLEIA).Correlative analyses and receiver-operator characteristic (ROC) analyses were completed to identify the value of the aforesaid measuring results.Results: The remarkably higher contents of KL-6 were identified in pSS-ILD patients in contrast to pSS patients [795.1±725.3U/ml vs 198.6±77.5U/ml] (P＜0.001). The optimum threshold of serum KL-6 for the diagnoses of ILD was 276.5 U/ml, and the sensitivity and specificity were 87.3% and 88.7%, respectively. The area under the curve (AUC) was 0.919 and the logistic regression analysis revealed that elevated KL-6 and decreased carbon monoxide diffusion capacity were independently correlated with the occurrence of pSS-ILD, and the increase of KL-6 levels was an independent risky factor for the occurrence of ILD (OR=1.019, 95%CI: 1.010~1.029). Conclusion: The serum KL-6 is a vital marker for the diagnoses of pSS-ILD, and when the KL-6 content is elevated, there is an underlying risk of ILD.
Analysis and verification of the conserved MYB binding element in the DFR promoter in Compositae
Authors: guo jialei , li fengzhen , shi guomin , zhao weimin , he tao 
Published: July 2022

Abstract
Anthocyanins are ubiquitous in Compositae and MYB regulates the expression of DFR and plays an important role in anthocyanin synthesis. Here, the regulation pathway that MYB protein of subgroup 6 in Compositae promotes dihydroflavonol reductase (DFR) expression was analyzed and verified by yeast one-hybrid experiment in Saussurea medusa. The results of the branch model and site model analysis revealed that MYB gene underwent purification selection, and the motif of bHLH protein [DE]Lx(2)[RK]x(3)Lx(6)Lx(3))R and anthocyanin-related motif ANDV underwent strong purification selection during evolution. DFR promoter analysis showed that there are MYB binding site (GAGTTGAATGG) and bHLH binding site (CANNTG) at the sense strand of 84–116 nucleotide residues from the start codon, and the two motifs are separated by 9–10 nucleotide residues, and this rule exists in DFR promoters of many Compositae plants. Yeast one-hybrid experiment proved that SmMYB1 can activate the promoter of SmDFR. Our results provide a reference for further functional studyof DFR gene in Compositae.
Predicting Damage to a Building During Earthquake
Authors: NANDWANI DINKY 
Published: July 2022

Abstract
Earthquake is one of the most hazardous natural calamities. It occurs due to sudden shaking of ground which is caused by movement of seismic waves. The tectonic plates are always slowly moving, but they get stuck at their edges due to friction. When the stress on the edge overcomes the friction, there is an earthquake that releases energy in waves that travel through the earth's crust and cause the shaking that we feel. The problem statement of this project is determining the degree of damage that is done to buildings, thus when an earthquake occur we can help identify safe and unsafe buildings, thus avoiding death and injuries resulting from aftershocks. Leveraging the power of machine learning is one viable option that can potentially prevent massive loss of lives while simultaneously making rescue efforts easy and efficient. During this study, earthquake prediction was performed, by training different Machine Learning models on dataset collected from hackerearth website. During this research, machine learning algorithms like Random Forest, Neural Network and XGBoost Mechanism are separately applied and accuracies in the training and testing datasets were compared to pick out the best model.
Nomograms for Predicting Survival in Patients with Micropapillary Bladder Cancer: A Real-World Analysis Based on the Surveillance, Epidemiology, and End Results Database and External Validation in a Tertiary Center
Authors: Liu Peng , Xu Lei , Shi Benkang , Zhang Qiujie , Chen Shouzhen 
Published: July 2022

Abstract
Background: The present study aimed to construct and validate nomograms that can be used to predict cancer-specific survival (CSS) and overall survival (OS) in patients with micropapillary bladder cancer.Methods: The data of 627 patients diagnosed with SCCB between 2000 and 2018 were obtained from the Surveillance, Epidemiology, and End Results (SEER) database. Patients were randomly divided into the training and internal validation sets (7:3). The Cox proportional hazards regression model was applied to evaluate the association between variables and survival and then nomograms were constructed to predict the survival of an individual patient. The performance of nomograms was validated by using calibration curves, concordance index, receiver operating characteristic (ROC) curves with the calculated area under the curve (AUC) and decision curve analysis (DCA) in the training and internal validation set. Data from 41 micropapillary bladder cancer patients at Qilu Hospital of Shandong University from 2000 to 2022 were collected for external validation.Results: Several independent risk factors were taken into the two nomograms (CSS and OS), including age, marital status, AJCC TMN stage, surgical approach, lymph node ratio, and tumor size while the OS nomogram additionally contained race. The concordance index of the training set, internal validation set, and external verification group were all over 0.7. The calibration curve indicated good consistence between the nomogram prediction and actual survival. Area under the curve and decision curve analysis results indicated great clinical usefulness of nomograms.Conclusions: The nomograms predicting the survival outcome of patients with micropapillary bladder cancer would provide a valuable tool to help clinicians to evaluate the risk of patients and make individual treatment strategies.