bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ensino Remoto Emergencial
Authors: Oliveira de Santana Novais Juliana , Flaviana Nascimento da Silva Isabel 
Published: August 2022

O presente trabalho tem como objetivo apresentar a experiência de uma escola de ensino fundamental anos finais da rede municipal de São José da Laje- AL com a oferta de aulas on-line durante o período de pandemia. Em tempos de distanciamento social, as aulas no formato não presencial se tornaram uma das poucas alternativas para o ensino e aprendizagem dentro das escolas públicas do Brasil. Com isso, surgiram novas necessidades e adequações no trabalho docente, já que as escolas passaram do ensino presencial para o ensino remoto emergencial de forma abrupta, trazendo mudanças em diversos aspectos, principalmente no que envolve o ensino/ aprendizagem e a prática docente. Dessa forma, a pergunta que buscamos responder é quais as metodologias e plataformas de ensino os professores de uma escola municipal de São José da Laje- AL têm utilizado nesse momento de ensino remoto emergencial? Para responder à pergunta, além do relato de experiência, fez-se necessário aplicar um questionário semiestruturado para 7 professores da escola pesquisada, bem como procurar por estudos que tratam do ensino remoto. O presente trabalho revelou que, apesar de todas as dificuldades do momento emergencial, os professores têm buscado se adaptar as novas necessidades
Brusatol Inhibits Proliferation, Migration, and Invasion of Nonsmall Cell Lung Cancer PC-9 Cells
Authors: Yang Lu-Ming , Zhou Wen-Min , Guo Qiao-Ru , Fan Xin-Yue , Huang Dong-Yu , Sun Xiao-Fei , Yuan Jie , Yu Hua , Chen Hu-Biao , Zhang Jian-Ye 
Published: August 2022

Objective:
The purpose of this study was to investigate the inhibitory effect of brusatol, a nigakilactone extracted from Brucea javanica, on lung cancer for development of therapeutic drugs. We explored the effects of brusatol on the proliferation, migration, and invasion of lung cancer PC-9 cells in vitro and analyzed the mechanisms involved.

Materials and Methods:
MTT assay was used to determine the effect of brusatol on the proliferative capacity of PC-9 and H1975 cells in vitro. The half-maximal inhibitory concentrations (IC50) were calculated and used as a reference for subsequent experiments. Variations in the number and size of tumor cell clusters were monitored by the colony formation assay as evidence for the effect of brusatol on cell proliferation. The effect of brusatol on the migration and invasion of PC-9 cells was evaluated using wound healing and transwell assays, respectively. Apoptosis in lung cancer cells was detected using the Annexin V-FITC/propidium iodide assay. The correlated anticancer mechanism was detected using Western blotting.

Results:
The IC50 values of brusatol acting on PC-9 and H1975 cells were 1.58 ± 0.30 mM and 31.34 ± 2.72 mM, respectively, according to the MTT experiment. In addition, brusatol suppressed PC-9 cell proliferation, migration, and invasion, as well as induced apoptosis, which may be related to the downregulation of epidermal growth factor receptor (EGFR), β-catenin, Akt, and STAT3 expression.

Conclusions:
Brusatol showed potent anticancer activity against lung cancer PC-9 cells, inhibiting the proliferative capacity and metastatic potential of PC-9 cells. Its anticancer effect may be related to the downregulation of EGFR, β-catenin, Akt, and STAT3.
microRNA Profiling and the Effect on Metabolic Biomarkers and Weight Loss after Laparoscopic Sleeve Gastrectomy
Authors: Hany Mohamed , Demerdash Hala M. , Ahmed Asmaa Abd Elhameed , Agayby Ann Samy Shafik , Ghaballa Mohamed , Ibrahim Mohamed , Maged Passent , Torensma Bart 
Published: August 2022

Background:
Epigenetic changes after bariatric surgery are of increasing interest; we evaluated the levels of two circulating microRNAs (miRNA-222 and miRNA-146a) before and after the laparoscopic sleeve gastrectomy (LSG) and the effect of weight loss on the levels of metabolic biomarkers.

Materials and Methods:
We prospectively evaluated patients pre- and 12 months post-LSG for percent excess weight loss (%EWL), miRNAs levels, metabolic biomarkers (leptin, ghrelin, peptide YY, and glucagon peptide-1 [GLP-1]) levels from August 2019 to September 2021.

Results:
Significant differences were observed in the miRNA146a-3p (median: 0.64 (0.012-2.68) vs. 1.07 (0.1-3.6); P = 0.019) and miRNA222-5p (median 1.80 (0.1–3.61) vs. 1.19 (0.1-3.68); P = 0.003) levels before and after (12 months) LSG; fasting leptin, ghrelin, insulin, total cholesterol, high- and low-density lipoproteins, fasting blood sugar (FBS), and triglyceride levels also showed significant differences. Significant changes were observed in postprandial values of glucagon-like peptide l (GLP-1) (P = 0.0001) and peptide YY (P = 0.0006) 12 months after LSG. Homeostatic model assessment of insulin resistance (IR) was significantly correlated with %EWL, miRNA146a, and miRNA222-5p (P = 0.002). Postoperatively measured miR146a-39 and miRNA222-5p showed significant coefficient of determination R
2 of 0.184 (P = 0.008) and 0.259, P = 0.0007 toward %EWL, respectively. Furthermore, significant correlations of miRNA146a were observed with FBS and IR.

Conclusions:
LSG-mediated weight loss affected the plasma levels of miR146a and miR222-5p. Due to the simultaneous decrease of ghrelin and increase of postprandial hormones (peptide YY and GLP-1), medical problems in patients with obesity were reduced. This study identified miRNAs as the new markers in the treatment, diagnosis, and therapeutic direction of patients with obesity.
Outcome of Percutaneous Cardiac Lead Extraction in Chronically Implanted Leads with Tight Rail Rotating Lead Locking Device
Authors: Sharma Prabhat , Agarwal Naveen , Singh Balwinder 
Published: August 2022

Aims:
Despite advances in lead extraction tools, percutaneous lead extraction is a complex procedure associated with morbidity and mortality. No standards or directives exist to guide the choice of extraction tool or approach, and all operators tend to have their preferred method. The data on removing chronically implanted cardiac leads are scarce in India; reporting outcomes with emerging extraction technology is therefore encouraged. This is the first data submitted for the chronic difficult to explant cardiac leads from India.

Materials and Methods:
Thirteen lead extraction procedures using the Spectranetics tight rail rotating dilator sheath at the tertiary care center over two years are described here.

Results:
All patients had chronically implanted leads (mean duration 10.4 years), and the pre-procedure venogram showed occluded left subclavian and brachiocephalic veins with extensive collateralization. All leads were extracted successfully using the rotating dilator sheath, and this kit also retained vascular access by venous recanalization. There were no other procedure-related complications, and all patients remained well with suitable lead parameters at 1-year follow-up.

Conclusions:
The tight rail rotating extraction tool is safe and effective in chronically implanted leads. Moreover, it helps preserve vascular access by recanalizing long tortuous occlusions. Its use across various centers and a larger number of patients will be required to confirm our results.
Pattern of electrocardiographic abnormalities in pediatric HIV/AIDS clients at Federal Medical Center, Abeokuta
Authors: Yusuf Musa Kayode , Olowu Adebiyi O , Uzodimma Chinyere C , Dedeke Florence IO 
Published: August 2022

Background:
Sub-Saharan Africa presently contributes about 70% of global HIV/AIDS population with little or no emphasis on the contribution of cardiovascular abnormalities to the associated morbidity and mortality in the region.

Objectives:
The objective is to determine the prevalence of electrocardiographic (ECG) abnormalities and association of such abnormalities with HIV/AIDS severity in terms of clinical manifestations and level of CD4 depletion.

Design:
A hospital-based cross-sectional case-control study.

Methodology:
One hundred and five (105) HIV-infected children attending HIV clinic and equivalent age- and sex-matched HIV un-infected controls attending pediatrics General Outpatient Clinics at FMCA were consecutively recruited over 8 months. They were evaluated clinically and had CD4 count, hematocrit, plasma calcium and potassium, and standard 12-lead ECG done.

Results:
Thirty-five (33.3%) of the subjects had ECG abnormalities compared with four (3.8%) in the controls (χ
2 = 28.34, P < 0.05). The left ventricular hypertrophy was the commonest (13.3%) among other detected abnormalities such as Q-wave abnormalities, right ventricular hypertrophy, and ventricular repolarization abnormalities. The detected abnormalities were not significantly associated with advanced clinical or immunological stage of HIV/AIDS (χ
2 < 4.0, P > 0.05).

Conclusion:
There was a high prevalence of ECG abnormalities in children with HIV/AIDS. These abnormalities occurred irrespective of the extent of the disease advancement. There is therefore a need for at least an ECG to identify from among HIV infected children those who may subsequently require echocardiography since the cost of echocardiography is presently too high and precludes its routine use in the Sub-Saharan Africa.
Cardiac troponin T reference interval of healthy Nigerian children aged 5–17 years
Authors: Nlemadim Anthony Chibueze , Okpara Henry Chima , Anah Maxwell Udo , Meremikwu Martin Madu 
Published: August 2022

Background:
Cardiac troponin T (cTnT), a biomarker for myocardial injury, reference values is unknown in Nigeria. The establishment and use of pediatric cTnT normative values may be better than the use of adult-derived cTnT values.

Aim:
The aim of this study is to determine cTnT reference interval among healthy Nigerian children.

Methods:
One hundred and thirty-two healthy children aged 5–17 years were consecutively recruited over a 9-month period after meeting the inclusion criteria. Blood was taken and the sera analyzed for cTnT by the electrochemiluminescence immunoassay method using high-sensitive assay. Data were analyzed using RefVal software and SPSS version 23.0.

Results:
The male: female ratio was 1.03:1 with median (interquartile range) serum cTnT of 5.1 (5.0–5.1) ng/L. The reference interval has a lower reference limit (2.5th percentile) of 5.0 (5.0–5.0) ng/L and upper reference limit (97.5th percentile) of 6.8 (5.7–7.2) ng/L. The 99th percentile of cTnT was 7.2 ng/L. Serum cTnT had weak association with age (rs[130] = 0.19, P = 0.033) but no significant relationship with body mass index-for-age-and-sex, sex and social class.

Conclusion:
This cTnT reference interval can be beneficial in low-middle-income settings who lack indigenous reference intervals. We recommend its use for the identification of myocardial injury among children instead of adult intervals to prevent under-treatment. Stakeholders are encouraged to make cTnT affordable to the less privileged.
Caracterización de los efectos que genera la crisis del COVID 19 en los condóminos del cantón Cuenca
Authors: Gomez Nieto Adriana , Guerrero Luzuriaga Aura del Cisne 
Published: August 2022

El presente estudio demuestra y evidencia las características que concluyeron en una disminución económicamente, teniendo como resultado un perjuicio en los ingresos mensuales de cada condómino, por ende el promedio de incumplimiento en el pago de alícuotas en los edificios de viviendas se incrementó, esto ha consecuencia desde que se dispuso el confinamiento obligatorio para evitar la propagación de la pandemia COVID 19 que afectó a nivel mundial, en marzo de 2020; este análisis para un mejor entendimiento y ejemplificación tomó como referencia la realidad, circunstancias y hechos dados en el Edificio Paseo del Puente ubicado en la ciudad de Cuenca provincia del Azuay en la Parroquia Huayna Capac en la Av. 12 de Abril y José Peralta, dentro del periodo de tiempo antes mencionado, a su vez hace referencia al conocimiento general de las consecuencias del confinamiento, en la que la mayoría de las personas tuvieron que suspender sus actividades laborales dejando de percibir sus ingresos completos, esto fue el factor principal en la que la investigación desarrollará su objetivo principal.
THE 3-DIMENSION PICTURES IN INCREASING THE STUDENTS ABILITY AND INTEREST TO WRITE DESCRIPTIVE COMPOSITION
Authors: Asrifan Andi , Rinantanti Yulini , Tang Syamsu , Nadirah Nadirah 
Published: August 2022

The aim of conducting this research are to find out whether or not using 3-Dimensional pictures is able to increase the ability of the students of SMP Negeri 3 Pangsid Kabupaten Sidenreng Rappang to write a descriptive composition. And to find out whether or not the use of 3-Dimensional pictures is interesting for the students in writing English. In this research, the researcher employed a cluster random sampling technique meaning two classes from five classes in the population were taken as the sample which represented the experimental and control group. The classes were selected randomly. The number of total samples was 60 students. The researcher used two kinds of instruments in collecting data namely writing test and questionnaire and calculating the mean score, standard deviation, frequency table, and the value of t-test to identify the difference between pretest and posttest by using inferential analysis in SPSS 21.0 program for the windows evaluation version. To calculate questionnaire data into a percentage, the researcher used the percentage technique using this SPSS 21.0 program for the windows evaluation version. The result of the research shown that the use of 3D-Pictures as an authentic material can improve the students’ writing ability. The writing ability of students who used 3D-Pictures as an authentic material and those who had just used conventional way had a significant difference. Therefore, it could be concluded that the Eighth-grade students’ of SMP Negeri 3 Pangsid Kabupaten Sidenreng Rappang have better writing ability by using 3D-Pictures as authentic material. And the use of 3D Pictures in teaching process particularly in writing skill was interesting and effective. It was proved by a mean score of students answer in the questionnaire showed that the students were categorized as interested.
THE APPLICATION OF COOPERATIVE LEARNING: JIGSAW II TECHNIQUE IN IMPROVING STUDENTS’ READING COMPREHENSION OF EXPOSITORY TEXT
Authors: Nurwanti Nurwanti , Asrifan Andi , Haedar Haedar 
Published: August 2022

The research was conducted to find out whether or not the use of Jigsaw II technique improves the reading comprehension significantly better than the use of the conventional method of the eleventh grade students of SMA Negeri 8 Takalar, it covered students’ literal comprehension, inferential comprehension and critical comprehension of expository text and whether or not the students are interested in the use of Jigsaw II technique in learning reading of expository text. This research method employed was quasi-experiment. The research data were obtained through the test and questionnaire which were analyzed by SPSS 17.0 program. Data of test were analyzed using T-test to know students’ reading comprehension in terms of literal, inferential, and critical of expository text. Data of the questionnaire were analyzed by using descriptive statistics to see the students’ interest in joining the reading class of expository text through Jigsaw II technique. The research findings indicated that (1) Jigsaw II technique gave a higher contribution to the students’ reading comprehension of expository text. The mean score of pretest of the experimental and control group was significantly different after treatment by using Jigsaw II technique. The mean score of posttest of the experimental group was higher than the control group (84.16 > 62.91). Thus, the use of Jigsaw II technique was effective. Besides, all the three levels of comprehension improved after doing treatment; the literal comprehension got the highest improvement was 92.19>76.69. It was followed by inferential comprehension which got 83.75>66.25, and critical comprehension which got76.56 > 42.81.
Governança corporativa e qualidade das informações contábeis
Authors: Zatta Fernando Nascimento , Oliveira Rodrigo Ribeiro de , Mattos Aliomar Lino , Rocha Alessandro Roberto , Gonçalves Wellington , Freitas Rodrigo Randow de 
Published: August 2022

Objetivo - O objetivo deste estudo é destacar a influência da governança corporativa na qualidade da informação contábil em empresas familiares, especialmente os principais mecanismos de governança que influenciam as propriedades da qualidade da informação contábil. Desenho / metodologia / abordagem - Com base em dados de 333 artigos de pesquisa, adotamos o método bibliométrico para mapear a literatura e também divulgar o conhecimento científico. Resultados - Os resultados obtidos, apoiados na literatura, indicam que os mecanismos de governança corporativa influenciam positivamente a qualidade da informação contábil nas empresas familiares. Originalidade / valor - A literatura seletiva e relevante forneceu fontes de informação para os autores do estudo discutirem a crescente importância das empresas familiares e o papel da governança corporativa e da qualidade da informação contábil em todo o mundo. O estudo inclui os principais autores que contribuíram para o desenvolvimento de um importante tema relacionado à complexidade da empresa familiar, o que constitui um desafio para pesquisadores e profissionais, reforçando a originalidade do presente estudo.
Visualization and Message Design Concepts of Presenting Statistical Data through Videos to Improve Understanding
Authors: Firmansah Muhammad Lukman Haris 
Published: August 2022

Learning statistics generally still presented in the form of stories in the books. This study aims to determine the visualization of the basic concepts of presenting statistical data using video. video designs stories into real stories experienced by students so that fact objectivity is created. it aims to make the messages in the story match the experiences experienced by students. this creating recaling knowledge and creating understanding. The research method used in this research is qualitative research with the phenomenological type, where the video is visually used to present messages, namely the concept of presenting data in tables and diagrams. The presentation technique in the video is in the form of a message demonstration that contains facts, concepts, procedures and principles. As for the data analysis used later, namely the observation data, interviews and documentation after using the video by means of data triangulasi. The research of this study were to compare the observation data, interviews and documentation in the form of student understanding data. Based on the observation data, it shows that students pay attention to the video and can explain the story again in the video. interview data shows and answers many type of data and its presentation. documentation data in the form of activity data in class at the second meeting compared to data at the first meeting without using video. Observations, interviews and the results obtained that observations with the aim of knowing whether students understand the sequence in the story is worth 74%, remembering the presentation data 86%, understanding the explanation of data in tables and diagrams 84%, explaining and explaining problems when the video is repeated 75%. This data was obtained when making observations and asking students when they were shown a video.
Analysis of the Company's Financial Performance Using the Du Pont System in the Building Construction Sub-Sector on the Indonesia Stock Exchange
Authors: Anggraini Putri , Febrianty Febrianty 
Published: August 2022

This study aims to determine the analysis of the financial performance of building sub-construction companies listed on the Indonesia Stock Exchange for the 2016-2020 period using the Du Pont System method. The Du Pont System includes the calculation of Net Profit Margin (NPM), Total Asset Turnover (TATO), Return On Investment (ROI), Equity Multiplier (EM) and Return On Equity (ROE). The research method used is a quantitative method with a descriptive approach and the data collection technique used is the company's annual report documentation technique. Based on the analysis and discussion, it can be seen that the Du Pont System analysis of building construction sub-sector companies listed on the Indonesia Stock Exchange for the 2016-2020 period shows a fairly good ROE performance, this is based on a comparison of industry standards. PT. Total Bangun Persada Tbk and PT. Wijaya Karya Bangunan Gedung Tbk is the company with the largest ROE, namely 18.37% and 17.18%, when compared to industry standards, these two companies are in very good condition. This indicates that the company is able to provide a very good return on the capital invested by the shareholders. The results of the research show that the average NPM ratio is in good condition which reflects the company can reduce costs so as to produce maximum profit. The average ratio of TATO and ROI shows a bad company condition that reflects the company's inefficient management of assets for sales and inefficient investment of assets. The results of the average EM show that the company's condition is quite good which reflects the company's efficiency in using its own capital to finance assets.
A IMPORTÂNCIA DA INTELIGÊNCIA ARTIFICAL NO PROCESSO EDUCACIONAL
Authors: Alves Guimarães Ueudison , Oliveira dos Santos Edinalva , Fernandes Daniella 
Published: August 2022

Este trabalho tem como objetivo tratar sobre a importância da inteligência artificial no processo educacional, sendo considerada como uma área de pesquisa no campo da ciência computacional que envolve diretamente as ferramentas tecnológicas que estão em constante evolução. Sabe-se que esse tipo de inteligência está relacionado à capacidade das máquinas/equipamentos aprenderem a pensar e agir como humanos. Mas deve-se saber que máquinas foram feitas e criadas de pessoas para pessoas, pois sempre o homem quem cria o seu algoritmo para a possível execução, sendo a linguagem de máquina sempre programada por pessoas. Portanto, o tema em estudo é oriundo de uma interação entre inúmeros fatores, tendo como principal deles o homem, que é o protagonista fundamental no referido processo, tanto da ciência, como também de experiências cotidianas e práticas diárias, onde a cada dia procura melhorar sempre de maneira colaborativa. Como método foram realizadas pesquisas bibliográficas de cunho qualitativo e caráter descritivo.
A Cultural History of Western Fashion
Authors: English Bonnie , Munroe Nazanin Hedayat 
Published: August 2022

Just as the clothes we wear can communicate our personality and how we want to be perceived, so fashion can reflect the politics and preoccupations of the society that produced it.
A Cultural History of Western Fashion guides you through the relationships between designer fashions, popular culture, big business and high-tech production, as well as traditional and social media. Exploring fashion’s interdisciplinary nature, English and Munroe also highlight the parallel evolution of clothing design and the other visual arts over the last 150 years.
This new edition includes expanded coverage of the build up to the First World War and brings this classic text up to date. There’s also a new chapter on ‘Smart Textiles and Technology’, exploring the work of Hussein Chalayan and Iris Van Herpen among others. There is also expanded coverage of the role of sustainability in the contemporary fashion industry, including biosynthetic textile production and Stella McCartney’s use of vegan leather.