bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survivor‐led guidelines for conducting trauma‐informed psychological therapy assessments: Development and modified Delphi study
Authors: Sweeney Angela , White Sarah , Kelly Katie , Faulkner Alison , Papoulias Stan , Gillard Steve 
Published: September 2022

AbstractBackgroundPsychological therapy assessments are a key point at which a person is accepted into a service or referred on. There is evidence of service users experiencing harm, dropping out of services and potentially experiencing poor outcomes because of inadequate assessment practices. Approaches to assessment tend to be developed by individual services, with a lack of research identifying what makes a good assessment.MethodsThis survivor‐led study, based in England, aimed to generate guidelines for conducting trauma‐informed psychological therapy assessments. The study was guided by a Service User Advisory Group and a Clinician Advisory Group. The study was conducted in three key stages: (i) identifying, modelling and drafting guideline content (ii) modified Delphi study and (iii) guideline finalization. Stage 1 was informed by literature reviews, qualitative research, data workshops with Advisory Groups and an expert consultation. Fifty‐nine people with relevant experiences then participated in a single‐stage modified Delphi (Stage 2). The guidelines were finalized through an analysis of Delphi open comments and a final expert consultation (Stage 3).ResultsThe guidelines evolved through each stage of the process, and all items were deemed important by >90% of Delphi participants. The final trauma‐informed guidelines contain eight principles, including ‘focus on relationships’, ‘from systems to people’ and ‘healing environments’.ConclusionsExperiential knowledge was key in generating the guidelines and conceptualizing content, with a consequent focus on areas, such as recognizing power differentials, understanding oppression as trauma and the relational aspects of assessments. Future research should focus on guideline implementation and investigate whether this impacts service user dropout, engagement with therapy, and outcomes.Patient or Public ContributionThis study is an example of survivor research, with several authors, including the study lead, identifying as survivors. We consider the ways in which our identities as survivor researchers impacted the study findings.
Effects of adding quinoa flour on the composite wheat dough: a comprehensive analysis of the pasting, farinograph and rheological properties
Authors: Zhang Yu , Wang Xiaoxuan , Guan Xiao 
Published: September 2022

SummaryRefined wheat breads are popular staples worldwide. Although they have desirable texture, they generally attribute to a high glycaemic index value. Adding whole‐grain flour to produce composite breads with both slower starch digestibility and ideal texture worth investigation. The present study investigated the pasting, farinographic and viscoelastic properties of the quinoa flour (QF)‐wheat flour (WF) composite dough. QF addition reduced the peak, final, breakdown and setback viscosities of the composite flour, indicating that starch gelatinisation was inhibited and retrogradation was slowed. QF addition increased G′ and G′′, while decreased tan δ (G′′/G′), exhibiting that the elasticity prevailed over viscosity for the composite dough. Farinograph analysis showed that when QF addition exceeded 20%, the stability time decreased and weakening degree increased sharply. Although creep‐recovery tests showed that 40% of QF addition exhibited the highest resistance to deformation, it disrupted the gluten network and brought negative effects on the composite dough. Taken these together, the composite wheat dough containing 20% of QF exhibited ideal rheological properties comprehensively. These results might be useful to develop and optimise mixed‐grain breads with lower glycaemic index.
Plastic response to disruptions: Significant redesign of supply chains
Authors: Hughes Molly M. , Zhou Zenan , Zinn Walter , Knemeyer A. Michael 
Published: September 2022

AbstractA plastic response is a type of resilient response to disruption whereby a supply chain is significantly redesigned. This is in contrast to the most common responses to disruption emphasized in the extant resilience literature, in which restoration of a supply chain to its pre‐disruption state is typically the focus. Researching plastic responses is important because they differ greatly from restoration. A plastic response is a new way to operate, thus requiring implementation of major changes to the supply chain. Accordingly, a foundational premise is adopted to characterize a plastic response as (1) a significant redesign, (2) due to a pressing need, (3) requiring most or all of the following: acquisition of new skills, investment in new assets and leadership support, (4) a permanent new way to operate. Additionally, eight propositions are offered to serve as bases for further research. These relate to two fundamental issues: when are plastic responses most likely to be exercised and how to enable plastic responses. The propositions were developed through qualitative data analysis and informed by change management theory. The data were collected from in‐depth interviews with global corporations in a variety of industries. Theoretical contributions and managerial implications are offered at the end.
First identification of Nocardia seriolaeGapA adhesion function and its three B‐cell epitopes with cell‐binding activity
Authors: Guo Jiajing , Yue Xiaozhen , Chang Jiaojiao , Zhang Zhenyuan , Li Jinnian , Liu Xuelan 
Published: September 2022

AbstractFish nocardiosis mainly caused by Nocardia seriolae (N. seriolae) is a serious threat to aquaculture. Bacterial adhesion to host cells mediated by adhesin is an initial step of pathogenesis. But it is not clear whether glyceraldehyde‐3‐phosphate dehydrogenase (GapA) is an adhesin of N. seriolae. Here, recombinant GapA protein (rGapA) was prokaryotic expressed, and its role in the bacterial adhesion to Ctenopharyngodon idella kidney cells was investigated by indirect immunofluorescence, protein‐binding assay and adhesion inhibition assay. The results showed that an obvious green fluorescence was observed on the surface of the cells co‐incubated with rGapA protein; the cytomembrane proteins of the cells pretreated with rGapA could react with anti‐rGapA antibody; and the antibody significantly inhibited the adhesion ability of the bacteria. Subsequently, B‐cell linear epitopes of GapA protein were identified by using a immunoinformatics approach combined with peptide ELISA and Western blot for the first time. It was found that four predicted epitopes (Ep58‐69, Ep139‐150, Ep186‐197, Ep318‐329) could all react with anti‐rGapA antibody and obviously inhibit the immunoreactivity between rGapA and anti‐rGapA antibody, and they were confirmed as indeed B‐cell linear epitopes of the protein. Furthermore, flow cytometry analysis found the percentage of positive cells co‐incubated with FITC‐labelled epitope peptides (Ep139‐150, Ep186‐197, Ep318‐329) was significantly higher than those in the FITC‐labelled Ep58‐69, unrelated control peptide and cell control. Collectively, GapA is an adhesin of N. seriolae, and epitope peptides (Ep139‐150, Ep186‐197, Ep318‐329) possess cell‐binding activity, which are potential candidates for developing a multiple epitopes‐based adhesin vaccine against fish nocardiosis.
A cost‐effective tsCUT&Tag method for profiling transcription factor binding landscape
Authors: Wu Leiming , Luo Zi , Shi Yanni , Jiang Yizhe , Li Ruonan , Miao Xinxin , Yang Fang , Li Qing , Zhao Han , Xue Jiquan , Xu Shutu , Zhang Tifu , Li Lin 
Published: September 2022

ABSTRACTKnowledge of the transcription factor binding landscape (TFBL) is necessary to analyze gene regulatory networks for important agronomic traits. However, a low‐cost and high‐throughput in vivo chromatin profiling method is still lacking in plants. Here, we developed a transient and simplified cleavage under targets and tagmentation (tsCUT&Tag) that combines transient expression of transcription factor proteins in protoplasts with a simplified CUT&Tag without nucleus extraction. Our tsCUT&Tag method provided higher data quality and signal resolution with lower sequencing depth compared with traditional ChIP‐seq. Furthermore, we developed a strategy combining tsCUT&Tag with machine learning, which has great potential for profiling the TFBL across plant development.
The online mindset intervention ‘The Growth Factory’ for adolescents with intellectual disabilities: moderators and mediators
Authors: Verberg F. , Helmond P. , Otten R. , Overbeek G. 
Published: September 2022

AbstractBackgroundThe online mindset intervention The Growth Factory (TGF) has shown promising effects—increasing growth mindsets and perseverance and decreasing mental health problems among youth with intellectual disabilities (ID). Studying moderators and mediators of intervention effects is essential to elucidate for whom and why TGF works. Using a randomised controlled trial design, we examined youth's baseline mindset, gender, age, level of ID and intervention satisfaction as moderators of TGF effects and examined whether the intervention effects of TGF on improvements in mental health were mediated by perseverance.MethodsThe sample consisted of 119 participants with mild to borderline ID (Mage = 15.83;SD = 2.23), randomly assigned to the intervention (n = 60) or passive control group (n = 59). Participants reported mindsets, perseverance, internalising, externalising, attention and total mental health problems at pre‐test, at post‐test and at 3‐month follow‐up. Additionally, youth in the intervention group graded their satisfaction with a score at the end of each session.ResultsFindings indicated that the effectiveness of TGF was not affected by participants' baseline mindsets, age and ID level. TGF was more effective in reducing internalising problems in girls and increasing perseverance in boys. In addition, in the intervention group TGF was more effective in improving internalising, externalising and total mental health problems for youth who reported higher levels of intervention satisfaction at post‐test. Finally, TGF indirectly decreased internalising and externalising problems at follow‐up through improvements in perseverance reported at post‐test.ConclusionsTGF offers a universal, ‘add‐on’ mindset intervention complementing usual care programmes. It improves mindsets, perseverance and mental health in youth with ID. Both practical and theoretical implications are discussed.
Repeat use of short‐term credit: The case of deposit advance products
Authors: Chin Alycia , Romeo Charles J. 
Published: September 2022

AbstractEvery day, consumers borrow using short‐term credit products. Relatively little is known about “Deposit Advance Products” (DAP), short‐term, small‐dollar loans offered to checking account customers. We examine (1) how DAP borrowing changes with repeat use and (2) how consumers use DAP in conjunction with other credit. By analyzing transaction‐level data on more than 100,000 checking accounts over an 18‐month period, we find that consumers' DAP borrowing evolves. With repeat borrowing, consumers take credit for a longer time, increasingly withdraw new loans within a week of repaying prior ones, and borrow more. Additionally, consumers with repeat DAP use are more likely to simultaneously borrow using overdraft. Together, this evidence suggests that DAP may provide inadequate credit for consumers. We discuss implications for the short‐term credit market.
A bibliometric and visualized research on global trends of abdominoplasty, 2011–2021
Authors: Xi Tingting , Guo Rong , Wu Xuemei , Jiang Hua , Xiong Jiachao 
Published: September 2022

AbstractObjectivesPatients with multiple pregnancies, multiple pregnancies, and a history of severe obesity, the abdominal wall muscles, and skin exhibit rectus abdominis separation and skin laxity due to prolonged overstretching, which causes damage to both the patient's appearance and health. Abdominoplasty is a surgical solution to the problems of separation of the rectus abdominis muscle and laxity of the skin of the abdominal wall under direct vision, which is important for patients with the above problems. Currently, many studies have been reported on abdominoplasty, however, no reverent bibliometric analyses of abdominoplasty have been published.MethodsIn this study, we screened 1,119 studies on abdominoplasty between 2011 and 2021 based on the Web of Science Core Collection (WOSCC) database and performed a bibliometric analysis.ResultsWe found that high‐quality research related to abdominoplasty has increased in the last decade, and the United States was the leading country in the field of abdominoplasty. Stanford university ranked first in number of publications and citations. Aesthetic surgery journal was the most productive journal, followed by the Plastic and reconstructive surgery and Aesthetic plastic surgery. In addition, bariatric surgery, venous thromboembolism, rectus diastasis, breast reconstruction and umbilicoplasty are the keywords of recent publications that are the focus of current research.ConclusionThis study provides a comprehensive analysis and visualization of global research trends on abdominoplasty from 2011 to 2021, and improvements in abdominoplasty to reduce the incidence of postoperative complications will remain a focus of future research.
Insurance demand experiments: Comparing crowdworking to the lab
Authors: Jaspersen Johannes G. , Ragin Marc A. , Sydnor Justin R. 
Published: September 2022

AbstractWe analyze an insurance demand experiment conducted in two different settings: in‐person at a university laboratory and online using a crowdworking platform. Subject demographics differ across the samples, but average insurance demand is similar. However, choice patterns suggest online subjects are less cognitively engaged—they have more variation in their demand and react less to changes in exogenous factors of the insurance situation. Applying data quality filters does not lead to more comparable demand patterns between the samples. Additionally, while online subjects pass comprehension questions at the same rate as in‐person subjects, they show more random behavior in other questions. We find that online subjects are more likely to engage in “coarse thinking,” choosing from a reduced set of options. Our results justify caution in using crowdsourced subjects for insurance demand experiments. We outline some best practices which may help improve data quality from experiments conducted via crowdworking platforms.
The therapeutic and preventive effects of a canine‐origin VB12‐producing Lactobacillus on DSS‐induced colitis in mice
Authors: Zhang Ping , Li Benrui , Mu Jiaxin , Liu Dandan , Zhang Guoying , Mao Xinru , Huang Kehe , Waldron Kevin J. , Chen Xingxiang 
Published: September 2022

AbstractVitamin B12 (VB12) plays vital roles as a cofactor in reactions related to biosynthesis and metabolic regulation. Animals with diarrhoea from intestinal inflammation are susceptible to VB12 deficiency due to dysfunctional absorption. No current medications for canine intestinal inflammation can simultaneously act as VB12 supplements. Here we have tested a strain of VB12‐producing Lactobacillus, to investigate its safety in healthy dogs and test for hypothesized therapeutic and preventive effects on murine colitis. Results from enzyme‐linked immunosorbent assay, histopathological analysis, and quantitative polymerase chain reaction showed normal physical conditions of healthy dogs given Lactobacillus, and blood biochemical indices showed no significant differences in markers, indicating safety of Lactobacillus to healthy dogs. The microbiota in animals receiving VB12‐producing Lactobacillus probiotic exhibited decreased abundance of Escherichia coli and concomitant increase in Lactobacillus. The probiotic supplement also resulted in downregulation of proinflammatory cytokines in murine colon tissues, reduced myeloperoxidase activity and malondialdehyde level, and significantly increased serum VB12 level and decreased homocysteine in therapeutic and preventive experiments. Moreover, Lactobacillus supplement decreased colonic inflammation and injury, improved gut microbiota, and ameliorated VB12 deficiency as an adjunctive therapy. We conclude this product is potentially beneficial for efficient therapy and prevention of VB12 deficiency form intestinal inflammation in canine clinical practice.
Dietarysupplementation of 25‐hydroxycholecalciferol as an alternative to cholecalciferolin swine diets: A review
Authors: Lütke‐Dörhoff Michael , Schulz Jochen , Westendarp Heiner , Visscher Christian , Wilkens Mirja R. 
Published: September 2022

Abstract25‐hydroxycholecalciferol (25‐OHD3) formed via hepatic hydroxylation from vitamin D, cholecalciferol, represents the precursor of the biologically active vitamin D hormone, 1,25‐dihydroxyvitamin D. Due to a higher absorption rate and the omission of one hydroxylation, dietary supplementation of 25‐OHD3instead of vitamin D3is considered to be more efficient as plasma concentrations of 25‐OHD3are increased more pronounced. The present review summarises studies investigating potential beneficial effects on mineral homeostasis, bone metabolism, health status and performance in sows, piglets and fattening pigs. Results are inconsistent. While most studies could not demonstrate any or only a slight impact of partial or total replacement of vitamin D3by 25‐OHD3, some experiments indicated that 25‐OHD3might alter physiological processes when animals are challenged, for example, by a restricted mineral supply.
Serum lipopolysaccharide‐binding protein levels and cardiovascular events in hemodialysis patients: A prospective cohort study
Authors: Lin Ting‐Yun , Chang Yu‐Kang , Wu Ming‐Yin , Wu Tsai‐Kun , Chen Chang‐Hsu , Lim Paik‐Seong 
Published: September 2022

AbstractIntroductionPatients with end‐stage kidney disease (ESKD) exhibit an elevated cardiovascular risk. Chronic inflammation is one of the main mechanisms of cardiovascular disease (CVD). Lipopolysaccharide has been proposed as a link between systemic inflammation and CVD. Herein, we evaluated whether lipopolysaccharide‐binding protein (LBP), a surrogate marker of lipopolysaccharide and consequent inflammation, is associated with cardiovascular events in ESKD.MethodsWe performed a prospective cohort study of maintenance haemodialysis patients. Baseline serum LBP levels were categorized into tertiles and also modelled continuously for analyses. Cox regression methods were used to evaluate the association of serum LBP levels with cardiovascular events.ResultsA total of 360 haemodialysis patients were included in this analysis. During a median follow‐up of 3.1 years, 90 (25.0%) patients had cardiovascular events. Patients in the upper tertile of serum LBP levels had a significantly greater risk of cardiovascular events [hazard ratio (HR) 4.87; 95% confidence intervals (CI), 2.12–11.15] than those in the lower tertile, independent of age, sex, hypertension, diabetes, CVD, dialysis vintage, body mass index, non–high‐density lipoprotein cholesterol, albumin, phosphorus, high‐sensitivity C‐reactive protein, and interleukin‐6. The association was consistent regardless of whether competing risk of death was accounted for (subdistribution HR 4.87; 95% CI, 1.96–12.11 for upper versus lower tertiles) or serum LBP was analysed as a continuous variable (HR 1.30; 95% CI, 1.02–1.66 per 1 SD increment).ConclusionsSerum LBP levels were independently associated with cardiovascular events in heomodialysis patients. LBP might serve as a novel biomarker for CVD in ESKD.
Emotional intelligence and coping strategies among intensive care unit nurses
Authors: Cichoń Jakub , Płaszewska‐Żywko Lucyna , Kózka Maria 
Published: September 2022

AbstractBackgroundStress is an integral part of daily work for nurses, especially those who work in intensive care units (ICUs). However, chronic stress can affect nurses' mental and physical well‐being, increasing their risk of burnout and decreasing the quality of care. A higher emotional intelligence (EI) level may be correlated with greater use of effective coping strategies, leading to a reduction of the adverse effects of stress.AimThis study aimed to examine the relationship between EI and coping strategies among adult ICU nurses in Poland.Study DesignA cross‐sectional survey design was used. Current adult ICU nurses in nine Polish hospitals were invited to participate. The survey instruments used were: the Polish version of the Schutte Self‐Report Emotional Intelligence Test, the Inventory to Measure Coping Strategies with Stress (Brief‐COPE), and a self‐constructed questionnaire.Results114/543 (21%) nurses completed the survey. ICU nurses showed an average level of EI (70.2%). The main stress coping strategies were active coping and planning, the rarest being substance use, behavioural disengagement, and denial. For nurses with a higher EI level, the most frequently used strategies included positive reframing (R = 0.43; p < .001), active coping (R = 0.38; p < .001), planning (R = 0.37; p < .001) and religion (R = 0.25; p = .006). Nurses were less likely to utilize strategies of behavioural disengagement (R = –0.32; p = .001) and self‐blame (R = –0.40; p < .001).ConclusionsEI may have an impact on coping strategies, as a higher EI level was correlated with the greater use of effective coping strategies in ICU nurses.Relevance to Clinical PracticeTraining in coping with stress and increasing EI may have a positive impact on reducing the risk of burnout in nurses and thus improving the quality of care delivered.
Environmental Engel Curves: A Neural Network Approach
Authors: Mancini Tullio , Calvo-Pardo Hector , Olmo Jose 
Published: September 2022

AbstractEnvironmental Engel curves describe how households' income relates to the pollution associated with the services and goods consumed. This paper estimates these curves with neural networks using the novel dataset constructed in Levinson and O'Brien. We provide further statistical rigor to the empirical analysis by constructing prediction intervals obtained from novel neural network methods such as extra-neural nets and MC dropout. The application of these techniques for five different pollutants allow us to confirm statistically that Environmental Engel curves are upward sloping, have income elasticities smaller than one and shift down, becoming more concave, over time. Importantly, for the last year of the sample, we find an inverted U shape that suggests the existence of a maximum in pollution for medium-to-high levels of household income beyond which pollution flattens or decreases for top income earners.