bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incident Early- and Later-Onset Type 2 Diabetes and Risk of Early- and Later-Onset Cancer: Prospective Cohort Study
Authors: Zhang Yin , Song Mingyang , Cao Yin , Eliassen A. Heather , Wolpin Brian M. , Stampfer Meir J. , Willett Walter C. , Wu Kana , Ng Kimmie , Hu Frank B. , Giovannucci Edward L. 
Published: November 2022

OBJECTIVE
We evaluated prospectively the association between incident early-onset (diagnosed before 40 years of age) and later-onset type 2 diabetes and early-onset (diagnosed before 50 years of age) and later-onset cancer risk.

RESEARCH DESIGN AND METHODS
We prospectively followed 228,073 eligible participants in the Nurses’ Health Studies for up to 38 years. Hazard ratios (HRs) and 95% CI were estimated using Cox models.

RESULTS
We documented 18,290 type 2 diabetes, 6,520 early-onset cancer, and 36,907 later-onset cancer cases during follow-up. In fully adjusted analyses, early-onset type 2 diabetes was associated with increased risk of early-onset total cancer (HR [95% CI] 1.47 [1.06–2.04]), diabetes-related cancer (2.11 [1.38–3.23]), and obesity-related cancer (1.75 [1.08–2.82]), and the risk elevations were restricted to those with a BMI at 18 years of age of ≥21 kg/m2 (total cancer: 1.75 [1.20–2.56]; diabetes-related cancer: 2.43 [1.50–3.94]; and obesity-related cancer: 1.84 [1.05–3.22]). Early-onset type 2 diabetes was associated with higher risk of later-onset diabetes-related and obesity-related cancer specifically among individuals with higher BMI at 18 years of age. Later-onset type 2 diabetes was associated with a higher risk of later-onset total cancer (1.15 [1.11–1.20]), diabetes-related cancer (1.17 [1.12–1.22]), and obesity-related cancer (1.18 [1.13–1.24]). In analyses based on refined timing, the HRs attenuated substantially with aging.

CONCLUSIONS
Incident early-onset type 2 diabetes was associated with increased risk of early-onset total cancer and diabetes- and obesity-related cancer, especially in those with higher BMI at 18 years of age. The impact of early-onset type 2 diabetes on cancer risk may be inherently stronger than that of later-onset type 2 diabetes.
Efficacy and Safety of Dapagliflozin by Baseline Insulin Regimen and Dose: Post Hoc Analyses from DECLARE-TIMI 58
Authors: Pollack Rena , Raz Itamar , Wiviott Stephen D. , Goodrich Erica L. , Murphy Sabina A. , Yanuv Ilan , Rozenberg Aliza , Mosenzon Ofri , Langkilde Anna Maria , Gause-Nilsson Ingrid A.M. , Bhatt Deepak L. , Leiter Lawrence A. , McGuire Darren K. , Wilding John P.H. , Sabatine Marc S. , Cahn Avivit 
Published: November 2022

<p> </p>
<p><strong>Objective:</strong> The cardiorenal benefits of adding SGLT2 inhibitors to patients on insulin, particularly those on intensive regimens which include short acting (SA) insulin have not been explored.</p>
<p><strong>Research design and methods: </strong>The DECLARE-TIMI 58 trial randomized 17,160 patients with type 2 diabetes to dapagliflozin or placebo for a median follow-up of 4.2 years. Cardiovascular, renal, metabolic and safety outcomes with dapagliflozin vs. placebo by insulin dose and regimen were studied by Cox regression models.</p>
<p><strong>Results: </strong>The study included 7,013 insulin users at baseline, with 4,650 (66.3%) patients on regimens including SA insulin. Insulin doses varied with 2,443 (34.8%) patients receiving <0.5 IU/kg, 2,795 (39.9%) 0.5-≤1 IU/kg and 1,339 (19.1%) >1 IU/kg. Dapagliflozin reduced cardiovascular death/hospitalization for heart failure among overall insulin users (HR [95% CI] 0.82[0.69-0.97]), and consistently in patients on insulin regimens with or without SA insulin (HR 0.83[0.67-1.03] and 0.78[0.57-1.07] respectively, Pinteraction= 0.75). No heterogeneity was observed by insulin dose (Pinteraction = 0.43). The HR for major adverse cardiovascular events with dapagliflozin among insulin users (HR 0.84[0.74-0.97]) was similar irrespective of regimen or dose (Pinteraction 0.75 and 0.07, respectively). Dapagliflozin reduced the rate of adverse renal outcomes overall, and consistently across subgroups of insulin users. Decreases in HbA1c, weight and systolic blood pressure with dapagliflozin were seen regardless of insulin dose or regimen. The known safety profile of dapagliflozin was unchanged in patients on intensive insulin regimens. </p>
<p><strong>Conclusions</strong>: The benefits and safety of dapagliflozin were maintained in high-risk patients receiving high-dose or intensive insulin regimens including SA insulin.</p>
Analisis Fluktuasi Cadangan Devisa: studi kasus Indonesia, Vietnam, dan Malaysia
Authors: Rangkuty Dewi Mahrani , Rusiadi Rusiadi , Ramadhani Kiki 
Published: November 2022

This study aims to analyze of fluctuations in foreign exchange reserves in three developing countries using time series data for the period 2000-2018 with the Research Method Of Panel Autoregressive Distributed Lag (ARDL). The results showed that foreign exchange reserves were the leading indicator in three developing countries (Indonesia, Vietnam, and Malaysia) but were unstable in the short run. In the long and short term, significant variables affect fluctuations in foreign exchange reserves in three developing countries, namely exports and foreign debt. It is recommended to the Government to increase exports rather than imports to increase gold reserves which can later increase output towards economic growth.
Peran Investasi Modal Manusia dan Modal Fisik dalam Meningkatkan Pertumbuhan Produktivitas Tenaga Kerja di Indonesia
Authors: Hutami Riske Yuliana , Riani Novya Zulva 
Published: November 2022

This study aims to analyze; (1) the effect of human capital investment which includes education (primary education, secondary education, tertiary education) and health variables on labor productivity growth in Indonesia (2) the effect of physical capital investment as proxied by Gross Fixed Capital Formation (PMTB) on labor productivity growth in Indonesia (3) the effect of human capital investment and physical capital investment on labor productivity growth in Indonesia. The data used is secondary data from 34 provinces in Indonesia in 2016-2020 obtained from related institutions. This study uses panel data regression with the Common Effect Model approach. The results show that (1) human capital investment which includes education variables (primary education, secondary education, tertiary education) and health, each has a positive and significant effect on labor productivity growth in Indonesia (2) physical capital investment as a proxy for Gross Fixed Capital Formation (PMTB) has a negative and insignificant effect on labor productivity growth in Indonesia (3) investment in human capital and physical capital together has a significant effect on labor productivity growth in Indonesia
DETERMINATION OF TERMINAL VELOCITY AND FLUID VISCOSITY USING FALLING BALL VISCOMETER WITH VIDEO TRACKER APLICATION
Authors: Syifa Naila Hilmiyana , Hartono Hartono , Sulhadi Sulhadi 
Published: November 2022

Abstract
The purpose of this study is to determine the terminal velocity and fluid viscosity using falling ball viscometer with video tracker application. The terminal velocity is obtained by videoing the ball falling into a tube 115 cm long and 5 cm in diameter which has been filled with fluid and then the video is analyzed using tracker application. The fluids used are oil SAE 20W-50 and glycerin. The balls used are namely as balls I, II, and III with diameters of 1,09cm, 1,56cm, and 1,57cm. Once the terminal velocity of the sphere is known, the fluid viscosity is obtained by using Stokes law principle. The terminal velocities of balls I, II, and III in oil SAE 20W-50 are 0.247m/s, 0.250m/s, and 0.187m/s, while the terminal velocities of balls in glycerin are 0.092m/s, 0.090m/s, and 0.065m/s. The average fluid viscosity of oil SAE 20W-50 and glycerin are 0,834Ns/m2 and 1,807Ns/m2.
STUDENT RESPONSE TO THE EFFECTIVENESS OF SIMPLE PROPS AS A PHYSICS LEARNING MEDIA IN CHARLES LAW MATERIALS AT SMA UNGGULAN BPPT DARUS SHOLAH JEMBER
Authors: Sulistiyowati Ayu , Mahardika I Ketut , Subiki Subiki , Afitah Siti Nur , Mukarromah Lailiyatul , Riskiyanti Tia Dwi 
Published: November 2022

Respon siswa terhadap efektivitas alat peraga sederhana sebagai media pembelajaran fisika pada materi hukum Charles di SMA Unggulan BPPT Darus Sholah Jember bertujuan untuk mengetahui pendapat siswa terkait alat peraga yang digunakan di kelas. Metode yang digunakan adalah metode deskriptif statistik. Instrumen penelitian ini menggunakan angket tertutup. Subjek penelitian yakni siswi kelas XI IPA SMA Unggulan BPPT Darus Sholah Jember yang berjumlah 21 siswi. Teknik analisa data dengan uji validitas dan reabilitas. Berdasarkan hasil uji validitas yang telah dilakukan, data sebanyak 10 pertanyaan dinyatakan valid dan uji reabilitas sebesar 0,875 dinyatakan reliabel. Hasil rata-rata persentase efektivitas dari keseluruhan pernyataan berjumlah 89,037 % tergolong sangat efektif. Artinya alat peraga sederhana pada materi hukum charles sangat efektif sebagai media pembelajaran fisika.
MODELING LARGE-ANGLE PENDULUM OSCILLATIONS WITH QUADRATIC DAMPING AND DAMPING ON THE STRING
Authors: Pratama Defrianto 
Published: November 2022

Penelitian ini bertujuan untuk menentukan pendekatan teoritis yang tepat untuk osilasi bandul nyata dengan simpangan sudut awal besar dan memperhitungkan faktor redaman udara. Rekaman video gerak osilasi bandul nyata dianalisis dengan menggunakan software Tracker, untuk mendapatkan data percobaan. Persamaan gerak osilasi bandul nyata dimodelkan dengan persamaan diferensial nonlinier orde dua dengan memperhitungkan redaman linier, redaman kuadrat dan redaman pada tali bandul. Persamaan gerak bandul diselesaikan dengan metode Runge-Kutta Orde 4 kemudian hasilnya dibandingkan dengan data percobaan. Pemodelan dengan memperhitungkan redaman kuadrat dan redaman pada tali lebih mendekati fenomena nyata pada gerak bandul dibandingkan hanya memperhitungkan redaman linier.
DETERMINING THE DAMPING FACTOR OF THE RULER IN WATER USING LOGGER PRO
Authors: Silaban Berkatdo , Panuluh Albertus Hariwangsa , Silaban Bajongga 
Published: November 2022

Penelitian ini bertujuan untuk mengetahui nilai koefisien redaman dalam air untuk penggaris dengan menggunakan tiga jenis bahan dan dua arah osilasi yang berbeda. Masalah penelitian adalah bagaimana koefisien redaman beberapa jenis zat padat apabila berosilasi di dalam air. Jenis zat padat yang diosilasikan yaitu penggaris yang bahannya terbuat dari aluminium,besi, dan stainless steel dengan panjang dan lebaryang bervariasi. Metode penelitian yang digunakan adalah eksperimen dengan sampel air pada suhu 200C dengan nilai viskositas sebesar 1,00 mPa.s terdapat pada kran laboratorium fisika Universitas Sanata Dharma Yogyakarta. Alat pengumpul data yang digunakan adalah Video Logger Pro, yang dianggap telah akurat dalam mencacah redaman untuk setiap kali melakukan pengamatan pada masing-masing jenis zat padat. Berdasarkan hasil penelitian dengan mengayunkan penggaris pada mode osilasi yang berbeda pada sudut deklinasi < 10 0, dengan variasi panjang dipotong 9,5 cm, kemudian masing-masing dipotong kembali dua kali dengan panjang 2 cm berikutnya, menciptakan tiga variasi panjang. Potong variasi lebar dari lebar awal 2,6 cm, kemudian potong lebar berikutnya 0,3 cm dua kali sehingga ada tiga variasi lebar. Berdasarkan hasil penelitian didapatkan bahwa semakin kecil momen inersia maka semakin kecil nilai koefisien redamannya.
Analysis of semigroups with soft intersection ideals
Authors: Sezgin Aslıhan , Orbay Metin 
Published: November 2022

Abstract
In this paper, semisimple semigroups, duo semigroups, right (left) zero semigroups, right (left) simple semigroups, semilattice of left (right) simple semigroups, semilattice of left (right) groups and semilattice of groups are characterized in terms of soft intersection semigroups, soft intersection ideals of semigroups. Moreover, soft normal semigroups are defined and some characterizations of semigroups with soft normality are given.
Personality traits in adolescents with the Internet Gaming Disorder. Part II
Authors: Pawłowska Beata , Potembska Emilia 
Published: November 2022

Abstract

Introduction: The aim of this study was to characterize types of gamers in terms of selected personality traits.

Material and methods: The study involved 576 individuals aged 16 to 19 years. The participants were surveyed using Gough and Heilbrun’s ACL, the Coping with Stress Questionnaire, and the Psychological Inventory of the Aggression Syndrome.

Results: The four types of online gamers identified in the first part of the study reported in this paper differed significantly in the following personality characteristics: self-image, coping styles and aggression types.

Conclusions:

1. Individuals severely addicted to Internet gaming, significantly more often than those addicted moderately, mildly or not addicted at all, used escapist and emotional coping strategies and responded with auto-aggression, and physical and displaced aggression. Compared to the respondents not addicted to online gaming, they had a more negative self-esteem and were characterized by greater impulsivity, hostility, and were less responsible and autonomous.
2. Adolescents moderately addicted to gaming, compared to their non-addicted peers, were characterized by greater hostility, impulsivity, proneness to conflict, tendency to humiliate others, and verbal, physical and indirect aggression.
3. Young people with mild online gaming addiction, significantly more often than non-addicted adolescents, used psychoactive drugs, showed self-aggressive behavior and responded with displaced aggression in situations of stress.
LIII. International Scientific Conference KoKa 2022 September 7 – 9, 2022, Kočovce, Slovak Republic
Authors: Polóni Marián , Chríbik Andrej 
Published: November 2022

Abstract
Faculties of Mechanical Engineering, especially their Departments of Internal Combustion Engines, began conferences with a later designation KOKA (or KoKa) in the year 1969. These were initially focused on the research of the combustion engines. This was later accompanied also by research of the vehicle powertrains and drive units in general. Latest of these conferences was organized by the Institute of Transport technology and Engineering Design, SjF, STU in the year 2022 in the mansion house Kočovce.
Measuring the Operating Parameters of Electric Vehicles
Authors: Pícha Štěpán , Kotek Martin , Hartová Veronika , Štekerová Veronika 
Published: November 2022

Abstract
Electric vehicles are growing in popularity and are reviving a much disused powertrain in the vehicle sector. This paper deals with the measurement of driving performance of electric vehicles. For twelve selected vehicles, the parameters given by the vehicle manufacturer and measured during individual runs were compared. The measurements were carried out on a predetermined route, divided into several parts. The data obtained here not only serve to compare the parameters, but also to determine the degree of dependence of the individual measured parameters on the range of the vehicles.
Community Pharmacist Provision of Non-Dispensing Services in Health Professional Shortage Areas
Authors: Kessinger Haley , Landis Emily , DiPietro Mager Natalie , Kier Karen 
Published: November 2022

Individuals living in primary care health professional shortage areas (HPSAs) experience health inequities. Community pharmacists are healthcare professionals with an opportunity to provide care to underserved populations. The objective of this study was to compare non-dispensing services provided by Ohio community pharmacists in HPSAs and non-HPSAs. Methods: An electronic, IRB-approved 19-item survey was sent to all Ohio community pharmacists practicing in full-county HPSAs and a random sample practicing in other counties (n=324). Questions assessed current provision of non-dispensing services as well as interest and barriers regarding such services. Results: Seventy-four usable responses were received (23% response rate). Respondents in non-HPSAs were more likely to recognize their county’s HPSA status than those in an HPSA (p=0.008). Pharmacies in non-HPSAs were significantly more likely to offer 11 or more non-dispensing services than those in HPSAs (p=0.002). Nearly 60% of respondents in non-HPSAs reported starting a new non-dispensing service during the COVID-19 pandemic compared to 27% of respondents in full HPSA counties (p=0.009). Most commonly reported barriers to providing non-dispensing services in both county types included lack of reimbursement (83%), workflow (82%), and space (70%). Respondents expressed interest in learning more information about public health and collaborative practice agreements. Conclusion: While the need for non-dispensing services is great in HPSAs, community pharmacies in full-county HPSAs in Ohio were less likely to provide these services or begin novel services. Barriers must be addressed so that community pharmacists can provide more non-dispensing services in HPSAs to increase access to care and promote health equity.
UNSUR PROFETIK DALAM NOVEL KUBAH KARYA AHMAD TOHARI
Authors: Armet Armet , WS Hasanuddin , Abdurrahman Abdurrahman 
Published: November 2022

Penelitian ini dilatarbelakangi oleh pandangan bahwa adanya kesadaran masyarakat akan pentingya nilai profetik dalam kehidupan. Profetik berkenaan dengan sifat nabi yang mempunyai ciri sebagai manusia yang ideal secara spiritual-individual, juga menjadi pelopor perubahan, membimbing masyarakat ke arah perbaikan dan melakukan perjuangan tanpa henti melawan penindasan. Penelitian ini bertujuan untuk mendeskripsikan profetik dalam novel Kubah karya Ahmad Tohari. Penelitian ini merupakan rancangan penelitian kualitatif dengan menggunakan metode deskriptif analisis. Berdasarkan analisis dan pembahasan data, dapat disimpulkan hasil penelitian sebagai berikut, yaitu profetik humanis menjadi profetik yang dominan dalam novel Kubah karya Ahmad Tohari, hal ini membuktikan bahwa peduli sesama makhluk Tuhan, saling memahami, dan bermoral dalam hidup bermasyarakat sangat penting. Profetik liberasi dalam novel Kubah karya Ahmad Tohari terlihat dari adanya pembebasan dari kebodohan dengan cara menjalankan pendidikan yang sebaik-baiknya. (3) realitas profetik transendensi dalam novel Kubah karya Ahmad Tohari ditemukan sebanyak 61 data. Profetik transendensi dalam novel Kubah karya Ahmad Tohari terlihat adanya dari sikap tokoh seperti selalu beribadah.
Comparison of the Effects of Haloperidol, Metoclopramide, Dexmedetomidine and Ginger on Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Authors: Reza Naemi Amir ,   Department of Surgery, Arak University of Medical Sciences, Arak, Iran, Kashanitabar Vahid ,   Department of Surgery, Arak University of Medical Sciences, Arak, Iran, Kamali Alireza ,   Department of Anesthesiology and Critical Care, Arak University of Medical Sciences, Arak, Iran,   Alireza Kamali, Department of Anesthesiology and Critical Care, Arak of Medical Sciences, Arak, Iran. E-mail: alikamaliir@yahoo.com. Phone: 00989181622810, Shiva Ashkan ,   Department of Surgery, Arak University of Medical Sciences, Arak, Iran
Published: November 2022

Nausea is a mental sensation of unease and discomfort before vomiting. Vomiting refers to the return of the contents of the upper gastrointestinal tract to the mouth caused by contractions of chest and abdomen muscles.
Postoperative nausea and vomiting is an unpleasant experience with high treatment costs. Therefore, this study aimed to compare the effects of haloperidol, metoclopramide, dexmedetomidine, and ginger on postoperative nausea and vomiting after laparoscopy.
This double-blind clinical trial was performed on all laparoscopy candidates at Valiasr hospital, Arak, Iran. The patients were randomly divided into four groups (haloperidol, metoclopramide, dexmedetomidine and ginger), and all patients underwent general anesthesia using fentanyl, midazolam, atracurium, and propofol. After intubation, tube fixation, and stable hemodynamic conditions, the patients received four ginger capsules with a hint of lemon. A group of patients received 25 μg of dexmedetomidine. In the Plasil group, 10 mg of metoclopramide was given 30 minutes before the completion of surgery. In addition, 0.5 cc of haloperidol (5 mg) was administered to a group of patients. Heart rate, blood pressure, and oxygen saturation were recorded from the beginning of surgery, every 15 minutes until the end of the surgery. Furthermore, the occurrence of nausea and vomiting was recorded during recovery, 2 and 4 hours after surgery. Data were then analyzed using the SPSS software v.23.
Eighty-eight patients were enrolled in the study. The youngest and the oldest were 30 years and 70 years old, respectively, and the mean age was 48.02 ± 9.31 years. Moreover, the number of women in the four groups was higher than that of men. Blood pressure in the dexmedetomidine group was lower than the other four groups (P <0.05). The lowest heart rate was observed in the haloperidol group, while the highest heart rate was seen in the plasil group (P <0.05). The occurrence of vomiting and nausea was not significantly different between the four groups (P <0.05).
Our results showed no significant difference in postoperative nausea and vomiting between the four drugs. Due to the hemodynamic changes induced by each drug, it is best to use these drugs based on the patient’s condition. Ginger is also a herbal remedy that has fewer side effects, and this drug can be a good option for patients when there is no contraindication.
A Study on the Efficacy of Empirical Antibiotic Therapy for Splenectomized Children with Fever
Authors: Bahoush Gholamreza ,   Department of Pediatrics, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran; Ali-Asghar Children Hospital,,   Ali-Asghar Children Hospital, Tehran, Iran,   Gholamreza Bahoush, Associate Professor of Pediatrics, Pediatric Hematologist and Oncologist, SIOP member, Ali-Asghar Children Hospital, Department of Pediatrics, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran. E-mail: bahoush.gh@iums.ac.ir. Phone: 00989121992316, Nojoomi Marzieh ,   Department of Community Medicine, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran
Published: November 2022

Thalassemia represents a heterogeneous group of inherited diseases characterized by the lack or reduced production of hemoglobin β-chains. Many patients with thalassemia require splenectomy. What should be considered in the evaluation and management of candidates for splenectomy is to cover vaccination against infections such as pneumococci and the implementation of antibiotic prophylaxis. This study aimed to investigate the effect of the antibiotic type on the outcome of acute post-splenectomy infection in patients with thalassemia.
This investigation is a retrospective cohort study. One hundred fifty medical records of hemoglobinopathy patients who underwent splenectomy were collected from the Ali-Asghar Hospital, Tehran, Iran. SPSS v. 20 and SAS v. 1.9 were used to analyze the data.
A total of 150 patients that were vaccinated against post-splenectomy infections and were under antibiotic prophylaxis underwent splenectomy. The most commonly prescribed drugs were ceftriaxone or cefotaxime (132 cases, 88%), followed by ceftriaxone plus clindamycin (5.3%), ceftriaxone plus amikacin (3.3%), clindamycin (1.3%), vancomycin plus amikacin (0.7%), and others (1.3%). In terms of treatment outcomes, 143 cases (95.3%) were treated with the same antibiotics, and 4 (2.7%) experienced a changed antibiotic regimen with vancomycin.
The results show that perceptions of treatment for fever in splenectomized children need to be changed, and most of them do not require hospitalization and initiation of broad-spectrum antibiotics such as vancomycin for initially refractory cases, and can only be treated with daily intravenous ceftriaxone.