bluuebunny/crossref_metadata_2025_split huggingface dataset:
SARS-CoV-2 harnesses host translational shutoff and autophagy to optimize virus yields: The role of the envelope (E) protein
Authors: Waisner Hope , Grieshaber Brandon , Saud Rabina , Henke Wyatt , Stephens Edward B , Kalamvoki Maria 
Published: March 2022

AbstractThe SARS-CoV-2 virion is composed of four structural proteins: spike (S), nucleocapsid (N), membrane (M), and envelope (E). E spans the membrane a single time and is the smallest, yet most enigmatic of the structural proteins. E is conserved among coronaviruses and has an essential role in virus-mediated pathogenesis. We found that ectopic expression of E had deleterious effects on the host cell as it activated stress responses, leading to phosphorylation of the translation initiation factor eIF2α and LC3 lipidation that resulted in host translational shutoff. During infection E is highly expressed although only a small fraction is incorporated into virions, suggesting that E activity is regulated and harnessed by the virus to its benefit. In support of this, we found that the γ1 34.5 protein of herpes simplex virus 1 (HSV-1) prevented deleterious effects of E on the host cell and allowed for E protein accumulation. This observation prompted us to investigate whether other SARS-CoV-2 structural proteins regulate E. We found that the N and M proteins enabled E protein accumulation, whereas S prevented E accumulation. While γ1 34.5 protein prevented deleterious effects of E on the host cells, it had a negative effect on SARS-CoV-2 replication. This negative effect of γ1 34.5 was most likely associated with failure of SARS-CoV-2 to divert the translational machinery and with deregulation of autophagy pathways. Overall, our data suggest that SARS-CoV-2 causes stress responses and subjugates these pathways, including host protein synthesis (phosphorylated eIF2α) and autophagy, to support optimal virus production.ImportanceIn 2020, a new β-coronavirus, SARS-CoV-2, entered the human population that has caused a pandemic resulting in 6 million deaths worldwide. Although closely related to SARS-CoV, the mechanisms of SARS-CoV-2 pathogenesis are not fully understood. We found that ectopic expression of the SARS-CoV-2 E protein had detrimental effects on the host cell, causing metabolic alterations including shutoff of protein synthesis and mobilization of cellular resources through autophagy activation. Co-expression of E with viral proteins known to subvert host antiviral responses such as autophagy and translational inhibition, either from SARS-CoV-2 or from heterologous viruses increased cell survival and E protein accumulation. However, such factors were found to negatively impact SARS-CoV-2 infection, as autophagy contributes to formation of viral membrane factories, and translational control offers an advantage for viral gene expression. Overall, SARS-CoV-2 has evolved mechanisms to harness host functions that are essential for virus replication.
Motivations for social network site use and users' well-being: mediation of perceived social support, positive self-presentation and honest self-presentation
Authors: Gao Wen , Wei Jianhua , Li Yu , Wang Dongxue , Fang Lele 
Published: March 2022

PurposeThis study aimed to investigate positive associations between three main motivations (social interaction, information and entertainment) for the use of social network sites (SNSs) and users' well-being, as well as the multiple mediating effects of perceived social support, positive and honest self-presentation.Design/methodology/approachA sample of 759 active users of SNSs (WeChat Moments, Qzone and Weibo) aged 14–43 years was measured with online questionnaires. Correlation analysis and structural equation modeling were implemented to examine the corresponding hypotheses.FindingsThe results showed the overall intensity of motivations was positively associated with users' well-being; perceived social support and positive self-presentation played intermediary roles and honest self-presentation and perceived social support had a chain mediation effect. However, the motivations of social interaction, information and entertainment indirectly affected users' well-being through three different mediation paths.Originality/valueAlthough some studies have investigated the effects of motivations (including social interaction, information and entertainment) for SNS use on users' well-being, there has not been a consistent conclusion. The findings may shed light on the motivations for SNS use and how they may affect people's well-being in the digital era, thereby promoting their healthy use of SNSs as well as improved interface design and user management of SNSs.
What are job seekers attracted to? Examining the importance of organizational attributes across four types of job seekers in Poland and France
Authors: Mauger Yohann , Bryant-Lees Kinsey 
Published: March 2022

PurposeThe current study has two major aims: (1) investigate the factor structure and importance ratings of attributes in France vs Poland and (2) compare the importance ratings of the attribute signals sent by potential employers during the recruiting process across four different types of job seekers (i.e. new entrants, short-term unemployed, long-term unemployed and currently employed).Design/methodology/approachFirst, using a confirmatory factor analysis (CFA), the authors compare the fit of several proposed models and identify the best fit using the combined job seeker sample. The authors then examine the fit of the selected model for the France and Poland samples separately. Finally, we compare the attribute importance rating factors across groups using a Country by Job Seeker multivariate analysis of variance (MANOVA).FindingsThe CFA results on the combined sample showed that a six factor-solution with two higher-order factors (organization- and job-attributes) provided the best fit and held for both France and Poland. MANOVA results showed a significant interaction between type of job seeker and country for organizational characteristics, and main effects of country and job seeker for work–life values and characteristics.Originality/valueMost past research on the importance of job attribute factors focused on new entrants in the United States. This study provides the first examination of job attribute factors across different countries, France and Poland, and other types of job seekers.
Unleashing family firms' potential to do more with less: product innovation efficiency, family involvement in TMTs and technological collaborations
Authors: Martínez-Alonso Rubén , Martínez-Romero María J. , Rojo-Ramírez Alfonso A. 
Published: March 2022

PurposeThis paper aims to examine the influence of family involvement in TMTs on product innovation efficiency and the contingent role of technological collaborations, combining insights from the resource-based view and the behavioral agency model.Design/methodology/approachThis study empirically develops and tests the hypotheses using a longitudinal sample of 3,852 firm-year observations from Spanish manufacturing firms over the period 2006–2016.FindingsThe results reveal that family involvement in TMTs positively influences product innovation efficiency. The results also show that such positive effect is weakened as technological collaborations increase, and varies according to the partner type with whom the cooperation agreement is established. Specifically, the findings indicate that collaboration with suppliers appear to be the least detrimental for product innovation efficiency in family firms, followed by collaborations with customers and research organizations.Practical implicationsFamily firms should consider appointing family members to their TMT to improve product innovation efficiency. Moreover, to enhance the effect of family management on product innovation efficiency, family managers should carefully select their technological partners.Originality/valueThis study is one of the first studies to theoretically explain and empirically demonstrate that family involvement in TMTs is a critical antecedent of product innovation efficiency and that technological collaborations moderate such link. Moreover, this study goes further in revealing that distinct types of partners have a differential moderating influence on the family involvement in TMTs-product innovation efficiency relationship. The results can be used to help managers and practitioners to boost innovation performance as well as to assist policymakers to design firm-level innovation policies to improve family firms' competitiveness.
Stakeholder engagement and SDGs: the role of social media in the European context
Authors: Mehmood Asad , Hajdini Johana , Iaia Lea , De Luca Francesco , Sakka Georgia 
Published: March 2022

PurposeThe authors aim to investigate which social media posts' characteristics result in higher stakeholder engagement in the European context.Design/methodology/approachThe authors apply chi-square automatic interaction detection (CHAID) method to categorize social media posts based on their engagement levels. The authors conduct analysis on the tweets published in 2019 by companies that draw up and publish a sustainability report on Global Reporting (www.globalreporting.org). The final sample is based on 3,045 tweets from 173 firms of different industries and countries.FindingsThe authors find that tweet characteristics, such as content type, industry type and country of a firm, significantly influence stakeholder engagement rate.Practical implicationsThe findings are useful for practitioners and stakeholders. Firm management should consider the most important Sustainable Development Goals (SDGs) concerning their business activities for engaging stakeholders and contributing to sustainable development.Originality/valueThe authors consider stakeholder theory and contribute to stakeholder engagement and sustainability debate. For this purpose, the authors focus on firms' communication of SDGs through social media. To the best of the authors’ knowledge, this is the first study which considers the SDGs’ communication to determine the most significant SDGs resulting in higher stakeholder engagement.
Effects of virtual stores' opaque exterior on store perceptions and purchase intentions
Authors: Han Haejoo , Park Sujin , Hyun Kyung Hoon 
Published: March 2022

PurposeA series of research has focused on how virtual reality (VR) technology itself influences consumers' perceptions and attitudes. However, little is known about consumers' unique perceptions and behaviours that can be generated by the specific factors of the virtual stores that they visit. Therefore, the authors examine how the specific aspects of the virtual stores that consumers see on screens – namely, the opacity of virtual stores' exterior design can impact consumer perceptions and behaviours.Design/methodology/approachAcross three studies, the authors employed 3D modelling software (Rhino 6 and Unity) and 3D architectural visualisation software (Twinmotion) to create 360° VR videos for the manipulation of the virtual store exterior design. The authors performed ANOVA and regression analyses with three studies, a total of 858 responses.FindingsResults showed that virtual stores' opaque exterior design can promote product preferences, and this link is serially mediated by store prestige perceptions and product quality perceptions. In addition, this effect is particularly prominent among those with higher involvement in design elements.Originality/valueBy suggesting important design variables to virtual stores, it advances the emerging literature on VR. Furthermore, to our knowledge, this research is the first to highlight the importance of exterior opacity of a virtual store, and it deepens our understanding of how the opaque exterior of virtual stores influences store perceptions and consumer behaviours.
Fostering consumer engagement with marketer-generated content: the role of content-generating devices and content features
Authors: Yang Qiang , Li Hongxiu , Lin Yanqing , Jiang Yushi , Huo Jiale 
Published: March 2022

PurposeThis research explores the impacts of content-generating devices (mobile phones versus personal computers) and content features (social content and achievement content) on consumer engagement with marketer-generated content (MGC) on social media. It also examines these factors' interaction effects on consumer engagement.Design/methodology/approachThe study analyzed MGC that 210 companies had posted to Sina Weibo over three years, testing the study’s proposed model with negative binomial regression analysis.FindingsThe study's results show that MGC generated via mobile phones attracts more consumer engagement than MGC generated via personal computers. MGC with more social features attracts more consumer engagement, whereas MGC with more achievement features reduces consumer engagement. The authors also found that MGC with more social features generated via mobile phones and MGC with more achievement features generated via personal computers lead to more consumer engagement due to the congruency of the construal level of psychological distance.Originality/valueThis research enriches the literature by exploring the effects of content-generating devices and content features on consumer engagement in the MGC context, which extends the research on consumer engagement with social media from the context of user-generated content to the MGC.
Refining mobile location-based service adoption: the lens of pull effect- and push effect-related motivations
Authors: Le Xuan Cu 
Published: March 2022

PurposeMobile location-based service (m-LBS) seems like a new class of personalized service due to location positioning technologies. This work aims to investigate consumer readiness (RED) toward m-LBS based on integrating pull effect- and push effect-related factors into the technology acceptance model (TAM).Design/methodology/approachAn online survey collected data from 423 participants, and the research framework was analyzed using structural equation modeling (SEM).FindingsThe results divulge that consumer RED is determined by TAM antecedents, including usefulness (USE) and ease of use (EOU). EOU motivates USE in m-LBS. Regarding pull effect-related factors, absorptive capacity (ABC) is the strongest positive factor influencing consumer RED to use m-LBS, followed by technology willingness (TWI) and innovativeness (INN). Moreover, INN, trust (TRU) and perceived risk (RIS) significantly influence USE and EOU.Originality/valueThis work endeavors to explicate customer RED toward m-LBS by incorporating some meaningful pull effect-related dimensions (i.e. ABC, TWI and INN) and pushing effect-related dimensions (i.e. RIS) into crucial antecedents rooted in TAM. Thus, the findings assist practitioners in developing marketing strategies by boosting pull effects and controlling push effects on customer engagement in m-LBS.
Experiential AR/VR: a consumer and service framework and research agenda
Authors: Zarantonello Lia , Schmitt Bernd H. 
Published: March 2022

PurposeThe paper focuses on extended reality technologies and their potential contribution to the improvement of services. First, it identifies extended reality technologies (AR/VR) as the most promising interfaces to enable an experiential consumption of the services. It then summarises their properties and discusses similarities and differences. Last, it maps these technologies onto a consumer psychology framework of experience to derive possible areas of future research.Design/methodology/approachThe authors conduct a literature review and present a conceptual framework of AR/VR contributions on experience.FindingsThe study provides an up-to-date literature review including AR and VR applications for consumer and service experience, as well as recommendations for possible research directions.Originality/valueWhereas previous contributions adopted the same, experiential approach but focused on different technology (e.g. AI) or considered multiple interfaces and their impact on the consumer journey (mostly transactions), this paper aims at digging deeper into AR/VR, while retaining an experiential view on consumption that best serves the contextualisation of AR/VR.
How and when does centralization affect the likelihood of passive leadership?
Authors: Bani-Melhem Shaker , Abukhait Rawan , Bourini Islam Faisal 
Published: March 2022

PurposeThis study empirically investigates the impact of organizational structure (specifically centralization) on the occurrence of the passive leadership. The authors also examine the mediating role of autonomy frustrations and the moderating effect of turnover intentions in these relationships.Design/methodology/approachUsing structural equation modelling as well as PROCESS macro (version 3.5), the research model is analysed based on a sample of 133 employee–supervisor dyads in various public sector organizations in Dubai.FindingsContrary to the study hypothesis and assumption, the results demonstrate that centralization has no significant direct effect on the occurrence of passive leadership; however, this effect found to be significant only via the mediating of autonomy frustrations (fully mediator). This influence is strengthening when a supervisor has the intentions to leave his/her organizations.Originality/valueThese findings point on how and why centralization can lead to occurrence of passive leadership.
The role of talent management and employee psychological contract on employer branding: a pragmatic conceptual model
Authors: Sandeepanie Madduma Hewage Ruchira , Gamage Prasadini , Perera Gamage Dinoka Nimali , Sajeewani Thuduwage Lasanthika 
Published: March 2022

Purpose
The purpose of the article is to investigate the role of talent management and employee psychological contract on employer branding and to develop a pragmatic conceptual model while identifying gaps between core concepts.

Design/methodology/approach
The archival method was adopted along with systematic review based on Khan et al.’s (2003) five steps of systematic literature review. The systematic review has enclosed published research articles between 1960 and 2022 in fields of human resource management (HRM), brand management and psychology. In total, 260 Articles were initially scrutinized, and 230 were systematically reviewed finally to explore core concepts, identify gaps and model development.

Findings
This study explored five gaps among key concepts based on systematic review and linked theories, namely, social exchange theory and signaling theory. A conceptual model has been developed to explore the impact of talent management on employer branding with mediating and moderating role of employee psychological contract.

Research limitations/implications
This study is limited to conceptual model development; nevertheless, there is enormous scope for empirically testing the model related to various global contexts in future studies.

Originality/value
The developed conceptual model is a vibrant contribution for future investigations of impact of talent management on employer branding with mediating and moderating role of employee psychological contract in diverse global contexts in wining “war for talent.” This study endows a momentous input to whole frame of HRM knowledge because it discourses significant knowledge gaps amongst relationships and effects of identified variables, which has not been formerly revealed.
Performance characterisation and printing parameter modelling of selective laser melting printed capillary wicks
Authors: Meng Xu , Tan Shujie , Ding Liping , Zhang Yicha , Chen Liheng 
Published: March 2022

Purpose
The objective of this study is to investigate the feasibility of using selective laser melting (SLM) process to print fine capillary wick porous structures for heat pipe applications and clarify the interrelations between the printing parameters and the structure functional performance to form guidelines for design and printing preparation.

Design/methodology/approach
A new toolpath-based construction method is adopted to prepare the printing of capillary wick with fine pores in SLM process. This method uses physical melting toolpath profile with associated printing parameters to directly define slices and assemble them into a printing data model to ensure manufacturability and reduce precision loss of data model transformation in the printing preparation stage. The performance of the sample was characterised by a set of standard experiments and the relationship between the printing parameters and the structure performance is modeled.

Findings
The results show that SLM-printed capillary wick porous structures exhibit better performance in terms of pore diameter and related permeability than that of structures formed using traditional sintering methods, generally 15 times greater. The print hatching space and infilling pattern have a critical impact on functional porosity and permeability. An empirical formula was obtained to describe this impact and can serve as a reference for the design and printing of capillary wicks in future applications.

Originality/value
This research proves the feasibility of using SLM process to printing functional capillary wicks in extremely fine pores with improved functional performance. It is the first time to reveal the relations among the pore shapes, printing parameters and functional performance. The research results can be used as a reference for heat pipe design and printing in future industrial applications.
Building political capital through corporate social responsibility: a microlevel focus on the role of business leaders
Authors: Borges Andreia , Ramalho Nelson 
Published: March 2022

Purpose
There are no management decisions deprived of ethical or political consequences. Political corporate social responsibility (CSR) has been highlighting this assertion but research at the microlevel on this topic is scarce. This study aims to contribute to the microlevel research by proposing a behavioral framework where leaders’ political skills are determinants of engagement in strategic CSR and perceived CSR leverages their ascribed legitimacy to perform a political role outside the boundaries of the organizations.

Design/methodology/approach
Building upon political CSR and critical realism theories, this study offers a general review on key political CSR microlevel concepts and examines multiple dimensions of CSR to explain the indirect effect between boards' political skills and political legitimacy.

Findings
This research suggests that high politically skilled leaders are associated to more CSR adoption which fosters higher legitimacy to act as political influencers. Among these, CSR activities directed toward community members and employees are seemingly the most successful from a political standpoint.

Originality/value
This study proposes a contemporary form of political influence to business leaders that, in contrast with other strategies such as lobbying or financing political campaigns, does not end up damaging corporate image and reputation. Also, this study proposes that not all CSR activities leverage corporate political legitimacy per se, therefore they do need to be differentiated. This study then offers a comprehensive future research agenda, including detailed suggestions for research designs and measurements.