bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Next Frontier in Intelligent Augmentation: Human-Machine Collaboration in Strategic Marketing Decision-Making
Authors: Hesel Nina , Buder Fabian , Unfried Matthias 
Published: October 2022

Abstract
The boundaries of AI in decision-making are shifting from the operational to the strategic level, according to a recent survey of 500 international high-level B2C managers. Companies with little AI experience in strategic decision-making name issues like insufficient budgets, the lack of the right technological infrastructure, a shortage of know-how inside their company and the unavailability of skilled staff as major obstacles for AI implementation in strategic decisions. Pioneers in this field see their biggest challenges in data-related issues, such as dealing with an insufficient database, a lack of transparency of algorithms and problems in sufficiently standardizing complex strategic decisions to apply algorithms. Generally, managers expect AI to play a greater role in shaping their company’s strategic path in the future. Businesses should address these developments by rethinking job descriptions and the necessary skills to prepare for a future of synergetic collaboration where humans and algorithms are joining forces.
Pengaruh Strategi Pembelajaran Aktif Tipe Crossword Puzzle Berbantuan Media Flip Book Terhadap Keaktifan Belajar IPA Siswa Kelas IV Sekolah Dasar
Authors: Febriyanti* Eka , Mayarni Mayarni 
Published: October 2022

The learning activities carried out in grade IV A and IV B elementary school in Bekasi were monotonous and teacher centered. It was marked by students who received only material without interaction with both teacher and peer, lack of courage in expressing opinions, asking questions, and answered questions so that student didn’t engage during learning. The research aims to see whether there is an impact on the active learning strategy, a type, a flip book with the activation of the study of grade IV student science. It employs a quantitative approach with a type of experimental quasi. The design used on this research is a non equivalent control group. Random samples were taken. The samples is students IV A and IV B at SDN Tridayasakti 03 with a total of 56. The instruments used are pretest and posttest of multiple choice, observation, and documentation. The data analysis consisted of normality test (shapiro wilk), homogeneity (fisher), and hypothesis (independent samples t-test) of a degree of = 0,05. The results of the hypothesis testing are obtained 7,112 1,683 and sig. (2-tailed) of 0,000 0,05 then is rejected and is accepted. This it can be concluded that the influence of active learning strategies is a typical, flip book type help against the science activation of the study the IV class of science students
ОБ’ЄКТИВНІ Й СУБ’ЄКТИВНІ ПЕРЕДУМОВИ МОДЕРНІЗАЦІЇ ПРОФЕСІЙНОЇ ТА СВІТОГЛЯДНО-МЕТОДОЛОГІЧНОЇ ПІДГОТОВКИ ВЧИТЕЛЯ
Authors: Ковальчук Володимир 
Published: October 2022

У статті розкрито становлення незалежної демократичної України, що супроводжується комплексною перебудовою всіх складових систем країни, зокрема й освіти. Однією з головних ланок реформи освіти в Україні є модернізація процесу підготовки педагогічних кадрів. Учитель, викладач завжди були провідними постатями в школі, закладі вищої освіти, такими вони залишаються і сьогодні.
Нині вища педагогічна школа України досить яскраво продемонструвала гнучкість і здатність до адаптації у нових історичних умовах. Водночас зберегла “виробництво” фахівців. Проте багато з них так і не працюють у сфері освіти. При цьому не можна не зважати на той факт, що більш-менш зберігся достатньо високий рівень підготовки педагогічних працівників, хоча за останні роки педагогічні заклади вищої освіти зазнали серйозних втрат: знизився рівень їх матеріально-технічного забезпечення, дещо зменшився обсяг наукових досліджень з окремих напрямків, виникла незадовільна ситуація з підручниками і навчальними посібниками, постійно загострюється проблема представництва у вищій школі молодої генерації науковців, знижується життєвий рівень викладачів і студентів, повільно реорганізовується система перепідготовки педагогів закладів вищої освіти. Тому проблема освітньої реформи і підготовки вчителів нової формації постає як актуальна проблема сучасної вищої школи.
ТЕХНІКИ РОЗВИТКУ КРЕАТИВНОСТІ ОСОБИСТОСТІ: ІСТОРІЯ, ТЕНДЕНЦІЇ, ДОСВІД
Authors: Ворожбіт-Горбатюк Вікторія 
Published: October 2022

У статті представлено досвід використання технік розвитку креативності під час реалізації практичної складової освітніх програм підготовки здобувачів першого (бакалаврського) рівня вищої освіти у Харківському національному педагогічному університеті імені Г.С. Сковороди.
Дослідження технік розвитку креативності здійснювалося відповідно до системного наукового підходу у єдності психолого-педагогічних і соціокультурних чинників особистісного та професійного становлення здобувача освіти.
Використано конструктивний ґенезисний метод для розкриття історичного дискурсу, метод історичний актуалізаційний – для виділення актуального досвіду у сучасних умовах, метод аналізу освітніх програм, порівняння навчально-методичного забезпечення освітнього процесу у Харківському національному педагогічному університеті імені Г.С. Сковороди, метод педагогічного спостереження для виявлення відповідності змісту засобам особистісного і професійного становлення здобувачів освіти в університеті.
Evaluation of the effectiveness of a moisturizing cream as an adjuvant in the treatment of eczema: A preliminary real-world study report
Authors: Gala Monil Yogesh Neena , Muchhala Snehal , Rathod Rahul , Mane Amey , Bhagat Seema , Kotak Bhavesh 
Published: October 2022

Objectives:
Eczema is a papulosquamous disease characterized by itchy, dry, rough, flaky, inflamed, and irritated skin on arms, inner elbows, backs of the knees, or head. Numerous skin conditions can be managed with the help of moisturizers. Venusia® Max is a moisturizing cream meant for eczema with a unique combination of four butters – shea, cocoa, mango, and aloe that act as emollients along with glycerin, propylene glycol, emulsifying wax, and cyclomethicone. The study’s objective is to assess Venusia® Max cream’s moisturizing efficacy when used as an adjuvant to the main line of treatment for eczema.

Material and Methods:
This monocentric, real-world setting study evaluates the effectiveness of Venusia® Max as an adjuvant, along with prescribed treatment in patients with eczema, versus prescribed treatment only (without Venusia® Max) as well as baseline. One hundred and twenty subjects enrolled in the study were divided in two groups: 1. Receiving Venusia® Max cream as an adjuvant, along with prescribed treatment and 2. receiving prescribed treatment only. The subjects were assessed for eczema area and severity index (EASI) scores, skin hydration using moisture meter-SC, transepidermal water loss (TEWL) using VapoMeter, and subject self-assessment of itching, cutaneous dryness, and burning sensation.

Results:
In the group with Venusia® Max cream, significant reduction in the EASI score, burning sensation, itching, and TEWL along with significant increase in skin hydration was observed when compared to baseline.

Conclusion:
Thus, Venusia® Max cream offers a novel and effective topical treatment for the dry skin of eczema patients.
GULA DARAH PUASA DAN JUMLAH SEL BETA TIKUS DIABETES SETELAH PEMBERIAN TEMPE DAUN YAKON
Authors: Muninggar Jodelin 
Published: October 2022

<p align="justify"><span style="font-family: 'Times New Roman', serif;"><span><span lang="fi-FI">Diabetes </span></span></span><span style="font-family: 'Times New Roman', serif;"><span>mellitus </span></span><span style="font-family: 'Times New Roman', serif;"><span><span lang="fi-FI">adalah penyakit metabolik ditandai hiperglikemia </span></span></span><span style="font-family: 'Times New Roman', serif;"><span>dan berpotensi terjadi komplikasi kronis pada organ tubuh. Tujuan penelitian menghitung kadar gula darah puasa (GDP) dan j</span></span><span style="font-family: 'Times New Roman', serif;"><span>umlah sel Beta pankreas dengan metoda Immunohystochemistry (IHC) pada tikus Sprague dawley yang diinduksi Streptozotocin setelah pemberian tempe daun Yakon (Smallanthus sonchifolia). Sejumlah 40 tikus jantan Sprague dawley usia 11-12 minggu dibagi menjadi 8 kelompok secara acak. Kelompok normal tidak mendapatkan perlakuan apapun. Kelompok DM (diabetes mellitus) mendapat induksi Streptozotocin, namun tidak mendapat tempe daun Yakon. Setelah induksi Streptozotocin 35 mg/kgbb, kelompok perlakuan 1, 2, 3, 4, 5 dan 6, berturut-turut mendapat tempe mengandung daun Yakon dosis 200 mg (P1), 400 mg (P2), 800 mg (P3), tempe (P4), teh daun Yakon (P5) dan Metformin 500 mg (P6). Perlakuan diberikan 60 hari. Sebelum terminasi, tikus diambil darah untuk pemeriksaan kadar gula darah puasa. Setelah terminasi, pankreas diambil dan dibuat slide preparat metoda IHC serta dihitung jumlah sel Beta pankreasnya. Uji statistik dengan One-Way ANOVA </span></span><span style="font-family: 'Times New Roman', serif;"><span>dan uji korelasi Pearson </span></span><span style="font-family: 'Times New Roman', serif;"><span>menggunakan SPSS 19 dan p</span></span><span style="font-family: 'Times New Roman', serif;"><span>&lt;0,05</span></span><span style="font-family: 'Times New Roman', serif;"><span>. Hasil penelitian menunjukkan GDP kelompok perlakuan P2 352 gr/dL terendah dibanding kelompok perlakuan lain. Sedangkan jumlah sel Beta pankreas, kelompok P2 (44) dan P3 (45) tertinggi dibanding kelompok perlakuan lain. Uji One Way ANOVA untuk kadar GDP kelompok normal-DM-P2 menunjukan bermakna (p=0,000). Uji One Way ANOVA untuk jumlah sel beta kelompok normal-DM-P2 menunjukan bermakna (p=0,048). Uji korelasi GDP dengan jumlah sel Beta Pankreas menunjukan kekuatan lemah (p=0,820; r=0,067). Pemberian tempe daun Yakon dosis 400 mg/kb BB mampu menurunkan GDP dan meningkatkan jumlah sel Beta pada tikus diabetes yang diinduksi Streptozotocin. Korelasi kadar GDP dengan jumlah sel Beta pankreas memiliki kekuatan yang lemah.</span></span></p>
KARAKTERISTIK FISIKOKIMIA DAN ORGANOLEPTIK SELAI TIMUN SURI (Cucumis melo l var reticulatus naudin) DENGAN BERBAGAI KONSENTRASI GULA DAN CMC
Authors: Hidayat Irvan , Kristiani Endang Bekti , Haryati Sri 
Published: October 2022

<p>Penelitian untuk mengetahui pengaruh konsentrasi gula dan CMC pada selai timun suri, terhadap karakteristik sifat fisikokimia dan organoleptik selai timun suri yang dihasilkan.Mengetahui perlakuan terbaik pada selai timun suri dengan konsentrasi gula dan CMC yang berbeda.Penelitian ini menggunakan rancangan acak kelompok (RAK) pola faktorial, dengan faktor A (konsentrasi gula) dengan 3 level (30%, 35%, 40%) dan faktor B (CMC) dengan</p><p>2 level (0,5% dan 0,75%). dan diulang 3 kali. Bahan yang digunakan adalah timun suri, gula,CMC dan asam sitrat. Variabel yang diamati adalah kadar air, pH, serat kasar viskositas, daya oles dan uji organoleptik (daya oles dan kesukaan).</p><p>Berdasarkan analisis sidik ragam (ANOVA) menunjukan bahwa konsentrasi gula dan CMC berpengaruh terhadap kadar air, serat kasar, viskositas, daya oles serta uji organoleptik dayaoles, tidak berpengaruh terhadap kesukaan. Perbedaan pengaruh perlakuan tidak disebabkan oleh adanya interaksi tetapi karena pengaruh faktor A (konsentrasi gula) atau faktor B (konsentrasi CMC).</p><p align="center">Perlakuan yang terbaik adalah A3B1 yaitu selai pada konsentrasi gula 40% dan CMC</p><p> </p><p>0,5% menghasilkan selai timun suri dengan kadar air 18,53%, pH, 3,40% serat kasar 4,40%, viskositas 57,50 cP, daya oles 1,87mJ, serta skor mutu hedonik daya oles 3,33 (mudah dioleskan) dan kesukaan 3,73 (suka – sangat suka).</p>
Karakteristik Sensori Kopi Arabica Dan Robusta Menggunakan Teknik Brewing Berbeda
Authors: Kinasih Anggraini , Winarsih Sri , Saati Elfis Anis 
Published: October 2022

<p class="BasicParagraph">Kopi Arabica dan Robusta saat ini memiliki daya tarik terutama di kalangan coffee shop. Penelitian ini bertujuan untuk mengetahui daya terima panelis melalui uji organoleptik dengan perbedaan teknik brewing terhadap kopi Arabica dan Robusta. Hasil yang didapat dari hasil penelitian yaitu rendemen kopi Arabica lebih besar dibandingkan Robusta yaitu 0,9916 %. Berat biji per 100 gram yang didapat kopi Arabica sebesar 0,175 gr dan jumlah biji kopi Robusta sebanyak 669 biji. Perhitungan jumlah biji yang rusak kopi Robusta lebih banyak, yaitu 196 biji rusak dalam 1 kg. Pengujian citarasa dilakukan oleh 4 orang panelis terlatih seperti barista dan roaster dan 8 panelis lainnya dengan pengujian organoleptic dan cupping test. Hasil uji organoleptic terbaik secara keseluruhan (overall) oleh teknik brewing yaitu teknik Vietnam Drip pada kopi Robusta dengan score 6 (sangat suka) dengan penambahan susu kental manis pada tekniknya.<strong></strong></p>
Brain aquaporin-4 expression in the rat septic model (immunohistochemical study)
Authors:  Shulyatnikova T.V. , Tumanskiy V.O. 
Published: October 2022

The study aimed to determine aquaporin-4 expression in different brain regions was performed in Wistar rats subjected to cecal ligation and puncture (CLP) septic model. The immunohistochemical study of aquaporin-4 was carried out in the sensorimotor cortex, white matter, hippocampus, thalamus and caudate nucleus/putamen regions between 20 and 38 h after CLP. From the 12th h after CLP all animals showed the progressive impairment of sepsis signs and therefore, 9 rats were euthanized between 20-38 h (“CLP-B”, non-survived); 11 animals survived up to 48 h (con­stituted “CLP-A”, survived). After operation, CLP-B group displayed regionally-specific dynamic increase in aquaporin-4 level in the brain mostly associated with astroglial capillary endfeet: by 23rd h in the cortex – 234.15%, by 24th h in the thalamus –129.47% and hippocampus – 101.36%, by 30th h in the white matter – 135.31% and by 38 h in the caudate/pu­tamen – 92.85%; with the highest increase in cortex: by 3.34 times. Heterogeneous and heterochronous aquaporin-4 elevation among brain regions indicates territories more and less susceptible for systemic toxic exposure in sepsis as well as points to diverse reactive responsiveness of local astroglial populations during specific time-period after CLP. The higher rates of aquaporin-4 in the cortex of non-survived animals in CLP model reflects the importance of aquaporin-4 increase in the mechanisms of sepsis decompensation.
Should renal resistive index be considered as a routine predictor in newly diagnosed acute hydronephrosis in patients with unilateral renal colic?
Authors: Dahmarde Hamid , Fazeli Faramarz 
Published: October 2022

Urinary tract stones are the most common causes of urinary tract obstruction, leading to patient hospitalization in the emergency room. This study is aimed to evaluate the use of the mean resistance index (mRI) to predict hydronephrosis in patients admitted for acute renal colic. This prospective study was performed on 100 patients who were admitted to the emergency department (ED) with unilateral renal colic (RC) problem. At the first visit, the following was done for all patients: 1. blood was taken from them for laboratory studies; 2. ECG and cardiological test; 3. plain film of the urinary tract; 4. аbdominal US; 5. bilateral color doppler ultrasound (CDUS) with renal RI measurement. Based on the information collected at different times during the experiment, patients were divided into two groups: the group that showed signs of dilatation (group A) and the group with hydronephrosis (group B). The obtained data were analyzed statistically by SPSS version 20. A mRI with a 0.68 cut off value was the most accurate (AUC:0.878), and Sensitive (90%) cut-off value for prediction of hydronephrosis development among patients presenting with RC and renal stone. This cut-off value also provided the highest positive (94%) and negative (76%) predictive values. CDUS with RI measurement is an easy and non-invasive method that provides useful information about urinary tract obstruction stones in patients with unilateral RC. In our study, this method was able to predict successfully the onset of acute renal dilatation. This was done with different levels of sensitivity, specificity, accuracy and diagnostic efficiency that were higher than ultrasound. Daily use of CDUS in ED can improve ultrasound, especially when other methods are contraindicated. For example, the methods by which the patient is exposed to radiation (pregnancy, allergies, renal failure, etc.) or intravenous injection of contrast agents (urography and CT).
Charactirestics of vitamin D level in patients with atopic dermatitis
Authors: Garibeh E. , Bondаr S.А. , Tokarchuk N.I. , Vyzgha Y.V. 
Published: October 2022

The peculiarity of the skin is that it acts not only as a place of synthesis of vitamin D, but also as an organ targeted for its biologically active form. The aim of our study was to analyze the level of vitamin D in patients with atopic dermatitis. There were examined 48 people aged between 18 to 55 years; they are residents of Vinnytsia and Vinnytsia region. Serum levels of vitamin D, total IgE and eosinophilic cationic protein (ECP) were determined in the subjects. The average level of vitamin D in the serum of patients with atopic dermatitis was 19.2 [11.3-25.4] ng/ml, which corresponded to a deficiency. Among those surveyed, vitamin D deficiency was found in 68.4±4.7% (n=26) while vitamin D insufficiency in 31.6±4.5% (n=12). The severe course of the disease prevailed among patients aged 18-40 years (63.33±8.79) % more than in the age group of 41 years and older, (36.67±8.8%, p<0.05; OR=2.98, S=0.53, 95% SI:1.04-8.52). The proportion of people with vitamin D deficiency and moderate severity of atopic dermatitis was 62.5% (n=10) with a median level of 14 [8.3–19] ng/ml, and patients with severe atopic dermatitis made up 90.9% (n=20) (χ²=4.6; p=0.023), in which the median level of vitamin D was 14 [8.3-19] ng/ml. Serum vitamin D levels were in the zone of deficiency in patients with moderate and severe atopic dermatitis. Vitamin D deficiency was significantly more common in the group of patients with elevated levels of allergic inflammation markers. A positive correlation of medium strength between the level of vitamin D and ECP in the serum of patients with atopic dermatitis (rs=0.53, p<0.001), was revealed.
Opium use and COVID-19 infection, a retrospective study in Iran
Authors: Afshari Mahdi , Shahramian Iraj , Salarzaei Morteza , Mirzaie Hadi , Parooie Fateme 
Published: October 2022

The situation of Covid-19 patients with opium consumption has not been comprehensively investigated especially in Iran. This study is aimed to investigate the effect of current opium addiction on the severity and outcome of the Covid-19 infection. During a retrospective cohort study, clinical, demographic and all variables related to the severity and death due to the Corona virus infection were collected from the medical records of patients hospitalized from February 2020 to June 2021 in the study area. The role of current addiction in the severity and outcome of the disease was investigated using Cox, logistic and linear regression models. Of 939 confirmed Covid-19 cases admitted during the study period, 70 (7.5%) patients were currently addicted. Multivariate reg­ression models showed that current opium addiction significantly increased the chance of endotracheal intubation (OR=2.96, p=0.005) and reduced the mean length of stay in hospital (beta coefficient =-0.42, p<0.0001). However, opium addiction did not change the risk of death (HR= 1.54, p=0.063) or O2 saturation (OR=1, p>0.99). Opium addiction can be associated with the severity of Covid-19 infection, but does not play a considerable role in the mortality of the patients.
Availability and chemical associations of cadmium in contaminated tropical soils amended with mineral and organic amendments
Authors: Carrillo-Zenteno Manuel Danilo , Alves-Fernandes Raphael Bragança , Ferreira-Fontes Renildes Lucio , Pereira-Jordão Cláudio 
Published: October 2022

A study was performed to evaluate the variation in pH, availability, and chemical associations of Cd in two previously contaminated Latosols amended with mineral and organic amendments. The Latosols were contaminated with Cd and amended with vermicompost, sugarcane f ilter cake, palm kernel pie, lime, phosphate rock, or zeolite. Cadmium availability was evaluated monthly in the contaminated soil/soil amendment mixtures with the DTPA and Mehlich-3 extractants for twelve months of incubation. At the end of this period, a sequential extraction procedure was performed in the mixtures to identify the Cd forms present in the several geochemical fractions. Lime immobilized Cd at a larger extension (60%), being the metal transferred to less available fractions. The Mehlich-3 extractant had a high correlation (0.96**) with the available fraction examined by the sequential extraction procedure. In general, organic amendments produced small ef fects on the f inal pH of soil/soil amendment mixtures as compared with the initial soil pH. Mineral amendments caused enhancement of soil pH and the most pronounced ef fect occurred with the use of lime.
Pengaruh Model Problem Based Learning Berbantuan Multimedia Animaker Terhadap Hasil Belajar IPA Siswa Kelas VIII MTs Negeri 2 Lombok Barat
Authors: Hadriwani Sirni , Jamaluddin Jamaluddin , Karnan Karnan , Yamin M. 
Published: October 2022

Model Problem Based Learning merupakan model pembelajaran yang menggunakan masah dunia nyata sebagai konteks bagi siswa untuk belajar menyelesaikan masalah dan berpikir kritis. Multimedia Animaker merupakan aplikasi software yang menawarkan berbagai kemudahan dalam membuat persentasi vidieo pembelajaran berbasis online atau web. Penelitian ini bertujuan untuk mengetahui pengaruh model Problem Based Learning berbantuan multimedia animaker terhadap hasil belajar IPA siswa kelas VIII. Jenis penelitian ini adalah Quasi Experimental atau Eksperimen Semu. Populasi penelitian ini adalah kelas VIII MTsN 2 Lombok Barat, sampel penelitian terdiri dari kelas VIII A sebagai kelas eksperimen dan VIII B sebagai kelas kontrol dengan tehnik purposive sampling. Desain penelitian menggunakan pre test post test control grup design. Jenis instrument pengumpulan data yang digunakan berupa bentuk tes dan wawancra. Data hasil belajar IPA kelas VIII diperoleh dari hasil pre test dan post test. Analisis data uji hipotesis dengan menggunkan uji one way anova (anova satu jalur) dengan taraf signifikansi 0,05 dengan bantuan aplikasi SPSS Ver 21.0. Hasil penelitian menunjukan nilai rata-rara pre test untuk kelas eksperimen sebesar 48,20 dan untuk kelas kontrol sebesar 44,60 sedngkan nilai akkir atau post test untuk kelas eksperimen sebesar 77,20 dan untuk kelas kontrol sebesar 70,40. Uji normalitas menggunakan rumus Kolmogrov-Smirnov, uji homogenitas menggunakan rumus levene’s dan uji anova. Bedasarkan hasil uji one way anova diperoleh nilai rerata kuadrat : 5202,400 dengan drajd bebas : 3 dan nilai f hitung 61,70 > F Tabel 4,10 dengan Sig. (p) : 0,000 sehingga Ho ditolak dan Ha diterima maka penggunaan model Problem Based Learning berbantuan multimedia Animaker berpengaruh terhadap hasil belajar IPA siswa kelas VIII. Kesimpulanya bahwa pembelajaran dengan model Problem Based Learning berbantuan multimedia berpengaruh secara signifikansi terhadap hasil belajar IPA siswa kelas VIII MTs Negri 2 Lombok Barat tahun ajaran 2022/2023.