bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indian Society and Women
Authors: Anju  
Published: February 2022

The condition of women had become very pathetic in ancient times, especially when the society changed from matriarchal to patriarchal society, since then women were marginalized and this is the reason that from ancient to modern times, women were treated as second-class citizens. being seen. In modern times, when India was independent, the situation had worsened further. Even after 73 years of independence, women are seen only as a responsibility and not as a complete citizen. In the traditional structure of Indian society, more emphasis is being given to women only to live under the protection of son, husband and father, whereas in the Indian Constitution, both men and women have been given equal rights. Even after getting equal rights, women are very backward socially, politically and economically. In Indian society, women are still being seen as a commodity, a commodity, and a toy for entertainment. Due to which today women are becoming victims of incidents of molestation, domestic violence, assault, rape etc. on a large scale. There is a dire need to change this attitude being adopted towards women so that women can also step towards paying attention to their overall development.

Abstract in Hindi Language
प्राचीन काल में महिलाओं की स्थिति अत्यंत दयनीय हो गई थी खासकर जब समाज मातृप्रधान से पितृसत्तात्मक समाज में परिवर्तित हुआ तभी से महिलाएं हाशिए पर चली गई और यही कारण है कि प्राचीन काल से लेकर आधुनिक काल तक महिलाओं को दोयम दर्जे के नागरिक के रूप में ही देखा जा रहा है। आधुनिक काल में जब भारत परतंत्र था उस समय तो स्थिति ओर ज्यादा खराब हो गई थी ।आजादी के 73 वर्षों के बावजूद भी महिलाओं को केवल एक जिम्मेदारी के रूप में देखा जाता है न कि एक संपूर्ण नागरिक के रूप में। भारतीय समाज के परंपरागत ढांचे में केवल महिलाओं को पुत्र ,पति और पिता के संरक्षण में जीवन यापन करने पर अधिक बल दिया जा रहा है जबकि भारतीय संविधान में औरत और पुरुष दोनों को एक समान अधिकार दिए गए हैं । समान अधिकार मिलने के बाद भी सामाजिक, राजनीतिक और आर्थिक रूप से महिलाएं काफी पिछड़ी हुई है। भारतीय समाज में महिलाओं को आज भी एक वस्तु ,माल दिल बहलाने वाला खिलौना के रूप में ही देखा जा रहा है। जिसके कारण आज बड़े स्तर पर छेड़खानी ,घरेलू हिंसा, मारपीट बलात्कार इत्यादि की घटनाओं की महिलाएं शिकार हो रही हैं। महिलाओं के प्रति अपनाए जा रहे इस नजरिए नजरिए को बदलने की सख्त जरूरत है ताकि महिलाएं भी अपने संपूर्ण विकास की तरफ ध्यान देने की ओर कदम बढ़ा पाए।
Therapy of Uveal Melanoma. A Review
Authors: Rusňák Štěpán , Hecová Lenka , Kasl Zdeněk , Sobotová Markéta , Hauer Lukáš 
Published: February 2022

The aim of intraocular melanoma therapy is to achieve local tumor control, reduce the risk of metastasis development, preserve the eyeball and possibly the visual function of the eye. The choice of therapeutic approach requires a comprehensive view and individual approach to each patient with uveal melanoma. Factors considered include local finding (location, tumor size and shape, tumor activity, central visual acuity, intraocular complications), age and the patient‘s overall physical and psychological condition, as well as the patient‘s wishes.
The most widely used method of uveal melanoma treatment is radiotherapy. The effect of radiation is caused by the absorption of ionizing radiation energy, the effect of radiation on the cell is manifested by cell death (depletion), or by a cytogenetic information change (mutation). Brachytherapy uses scleral applicators with radionuclide - ruthenium (Ru-106) applicators dominate in Europe and iodine (I-125) applicators in the USA. In external radiotherapy, the source of ionizing radiation is outside the patient‘s body. Both stereotactic radiosurgery and fractionated stereotactic radiotherapy are used. In the Czech Republic, treatment is carried out using Leksell gamma knife or CyberKnife, while proton therapy dominates in the world. The development of serious radiation complications (radiation retinopathy, neuropathy, neovascular glaucoma, toxic tumor syndrome, etc.) should be considered.
Surgical therapy involves a variety of invasive procedures. Iridectomy is performed for iris melanoma. Anteriorly located choroidal melanomas and / or ciliary body melanomas can be resolved by transscleral resection (exoresection). For posterior choroidal melanomas, a combination of external tumor irradiation with pars plana vitrectomy is used.
Enucleation is a method of choice in advanced tumors that cannot be effectively irradiated. Orbital exenteration is indicated in advanced tumors with extrabulbar spread or in relapsed tumor after previous enucleation.
Analysis of the number of registered patients whis rare diseases in some regions of Ukraine
Authors: Подгайна М. В. , Сліпцова Н. А. , Тутук В. В. 
Published: February 2022

Rare (orphan) diseases (RD) are a global priority for health systems. In Europe, including Ukraine, the disease is considered rare with a prevalence of 1 patient per 2,000 population. To date, by the orphanet data, 6,172 unique rare diseases have been discovered. An important issue today is the understanding and analysis of data on the prevalence of RD in Ukraine, which will effectively plan the need for therapy and predict its cost.
Aim of the investigation was to analyze the available data on the of the registered cases of orphan diseases among children and adults in all Ukraine’s regions and determining the share of each disease in the overall structure in terms of age group of patients.
The object of the in vestigation are data of the Department of Statistics of the Ministry of Health on the cases of rare diseases, that were registered in Ukraine as of January 2020 and Medical Genetics Center’s data. The study was conducted using informative methods of analysis (collection and data processing), systematization and generalization, mathematical and statistical calculations.
According to the Сenter’s of Medical Statistics of the Ministry of Health data the total number of registered patients was 10786 patients, of whom children accounted for 54%. Among given diseases the largest proportion of patients had been registered with a diagnosis of «juvenile rheumatoid arthritis» – 2,291 patients, most of whom, almost 80%, are children. Among 18 rare diseases, 11%, were registered only among pediatric patients: Pump's disease, Fabri's disease. It has been established that Kyiv, Poltava, Dnipro, Ivano-Frankivsk and Kharkiv regions had been characterized by the highest total number of orphan patients. Regions with the lowestregistered number of orphan patients – are Luhansk, Lviv, Kherson, Sumyand Volyn. There was no information on registered RDs in Chernivtsi, Odesa, Zakarpattia regions and Kyiv city from the Center for Medical Statistics of the Ministry of Health, but it was indicated the cases of four RDs in Odessa region and Kyiv city by newborn screening program in 2020, that has shown problems in the collection, centralization and coordination of the statistic information of RDs and needs to be resolved in the future at the state and regional levels.
A termelőszövetkezettől az udvari bolondig – az egyetem társadalmi szerepei a 21. században
Authors: Kováts Gergely 
Published: February 2022

Noha széles körű egyetértés van arról, hogy az egyetemek a társadalomban fontos szerepet töltenek be, arról már megoszlanak a vélemények, hogy pontosan miben is áll ez a szerep. Az elvárások nagyon sokrétűek és ellentmondásosak. A tanulmányban arra a kérdésre keresem a választ, hogyan lehetne rendszerezni az egyetem társadalmi szerepeit, és ez nyújt-e támpontokat a 21. századi egyetemmel szembeni kihívásokhoz (tudásmonopólium elveszítése, nemzetállamok gyengülése, a tudás relativizálódása). A javasolt keretrendszer két szempont mentén fogalmazza meg az egyetem társadalmi szerepeit: egyrészt a termelés jellege (termék/folyamat), másrészt a társadalmi, gazdasági és politikai berendezkedéshez fűződő viszony alapján (konszenzus/disszenzus). Ebből kiindulva négy társadalmiszerep-modellt mutatok be: a termelőszövetkezetet, a katalizátort,a világítótornyot és a görbe tükröt. A tanulmány végén a nézetek integrálhatóságát vizsgálom meg.
Kérdések és válaszok (?) a magyar felsőoktatásban: rektor kontra kancellár
Authors: Torma András 
Published: February 2022

A 21. század az információs forradalom évszázada, amikor nem az a kérdés, hogy lesz-e, van-e információ, hanem az, hogy a rendelkezésre álló forrásokban hol találom meg azt. A jelen tanulmány szerzője könnyű helyzetben volt ebből a szempontból, hiszen magyar joganyagot vizsgált. Olyan forrásból merített tehát, amely Magyarországon mindenki által, korlátlanul és ingyenesen hozzáférhető. A tanulmány középpontjában egyetlen törvény, a felsőoktatásról szóló 2011. évi CCIV. törvény és annak gyakorlata áll. Az a jogszabály, amely a hatálybalépését követő tíz évben kilencszáz (!) joghelyen módosult, ennélfogva bizonyosan nem tekinthető a magyar jogalkotás kősziklájának. Másfelől az a gyakorlat, a gyakorlati tapasztalatok sokasága, amelynek a szerző alanya volt, hiszen 2012. július 1. és 2013. augusztus 15. között a Miskolci Egyetem Állam- és Jogtudományi Karának dékánja, ezt követően pedig hét éven át az Egyetem rektora volt. Ebből az aspektusból vizsgálja a szerző azokat a joghelyeket, amelyeket problémásnak ítélt, különös figyelemmel a törvény 2014. évi módosítására, illetve a kancellári rendszer bevezetésére.
ANALISIS KEBUTUHAN PENGEMBANGAN INSTRUMEN EVALUASI PROGRAM DIKLAT PEMBERDAYAAN MASYARAKAT SISTEM MANAJEMEN
Authors: Andhito Kunto 
Published: February 2022

Penelitian bertujuan untuk memperoleh informasi, mendeskripsikan Pendidikan dan Pelatihan Pemberdayaan Masyarakat Sistem Manajemen Keselamatan (DPMSMK), Peneliti menggunakan metode kualitatif dengan cara mengumpulkan data dengan wawancara, kunjungsn lokasi, mempelajari dokument, dan mempelajari pustaka,(Yumaroh, Wahyu Lestari, 2014). Penelitian memperorleh data uji validitas item soal dan uji reliabilitas instrumen evaluasi pada prosedur pengujian instrumen evaluasi yang sudah memenuhi kriteria ciri tes yang baik. Program Diklat yang dinamis membutuhkan waktu yang lama untuk melakukan evaluasi, namun dengan inovatif teknologi menggunakan pengembangan instrumen evaluasi program Diklat berbasis online seluruh pertanyaan yang sering muncul pada saat berakhirnya program Diklat dapat dijawab dan faktor penghambat berubah menjadi faktor pendukung dalam pelaksanaan evaluasi program Diklat.
Comparison Between Hesperidin, Coumarin, and Deferoxamine Iron Chelation and Antioxidant Activity Against Excessive Iron in the Iron Overloaded Mice
Authors: Aalikhani Mahdi , Safdari Yagoub , Jahanshahi Mehrdad , Alikhani Mehrdad , Khalili Masoumeh 
Published: February 2022

ObjectiveIron accumulation in the brain leads to the development of Alzheimer’s and Parkinson’s diseases. Nowadays, iron chelation therapy is the best way to decrease the side effects of iron and amyloid plaques accumulation. Iron chelators are commonly used for the treatment of Alzheimer’s disease. Previous studies have shown that natural products such as phenol and flavonoid compounds could chelate heavy metals. In the current study, we examined the iron chelation activity of hesperidin and coumarin on the brain tissue of iron-overloaded mice.Methods48 NMRI male mice were divided into eight groups (n = 6). Six groups were treated with iron dextran (100 mg/kg/day) four times a week for 6 weeks. After stopping the injections for a month, five groups of iron-overloaded mice were treated with hesperidin, coumarin, and desferal four times a week subsequent for four subsequent weeks. Finally, the mice were anesthetized, and blood samples were collected from the ventricle of the heart for subsequent examination. The brain tissues were isolated and fixed in the 4% paraformaldehyde solution for Perl’s staining.ResultsThe results show that hesperidin and coumarin could strongly chelate excessive iron from the serum and deposit iron from the brain tissue compared to desferal group. Catalase and super oxidase activity were decreased in the iron-overloaded group, but in the treated group by hesperidin and coumarin, the enzyme’s activity was increased significantly.ConclusionHesperidin and coumarin, as natural products, are powerful options to chelate iron ions and increase the activity of antioxidant enzymes.
Olfactory Neuroblastoma: Surgical Treatment Experience of 42 Cases
Authors: Cai Xiao , Peng Zhouying , Zhang Hua , Fan Ruohao , Fang Yan , Xie Zhihai 
Published: February 2022

ObjectiveOur purpose was to estimate the safety and effectiveness of the endoscopic endonasal approach (EEA) in olfactory neuroblastoma (ONB) and determine whether preservation of the dura and olfactory bulb could be considered in selected patients.MethodsWe retrospectively reviewed patients diagnosed with ONBs between July 2010 and June 2021 at our institution, and collected data on demographic, disease stage, surgical approach, overall survival (OS), disease-free survival (DFS), and postoperative complications.ResultsThe study sample included 42 patients (8 treated for recurrence and 34 initial cases), 28 of which were men and 14 were women with a median age of 47.19 years. The mean duration from the beginning of treatment and follow-up time was 8.91 and 51 months, respectively. Among the 42 patients, 32 had unilateral lesions, and the rest had bilateral lesions. Patient symptoms were predominantly nasal, and four patients presented without any symptoms. The modified Kadish staging was A in three patients, B in 14 patients, C in 17 patients, and D in 8 patients. According to the preoperative examinations, five patients had cervical lymph node metastasis, and no patients had distant metastases. EEA was used in 38 patients, cranioendoscopic approach in 3, and open craniofacial approach in 1. The 5-year OS and DFS rates were 89.1 and 79.2%, respectively. The 2-year OS and DFS rates were both 89.1%. The overall surgical complication incidence was 9.52% (one cerebrospinal fluid rhinorrhea, one cervical hematoma, and two epileptic seizures).ConclusionThe present results support the importance of earlier treatment for advanced ONB and the fact that it is safe and efficacious to treat ONBs via EEA. The preservation of the dura can be considered for select patients—specifically those without skull base involvement and who underwent postoperative comprehensive therapy.
RETOS Y REALIDADES DEL DOCENTE DE PRIMARIA EN EL USO DE LA TECNOLOGÍA COMO HERRAMIENTA DE ENSEÑANZA EN TIEMPOS DE CONTINGENCIA
Authors: Armenta-Zazueta Lizeth , Castañeda-Campoy Carmen Vanessa , Domínguez-Ramírez Guadalupe 
Published: February 2022

El desarrollo de las TIC en el siglo XXI ha sido un proceso de cambios vertiginosos, impulsando a los gobiernos a implementar políticas públicas que permitan a las sociedades insertarse en la sociedad de la información y del conocimiento. El objetivo es describir las realidades y retos del docente de nivel primaria en el uso de la tecnología como herramienta para la enseñanza en tiempos de contingencia, mediante el método de investigación cualitativo fenomenológico, para comprender la experiencia del docente en la modalidad educativa a distancia. Este estudio se desarrolla bajo la perspectiva teórica-metodológica del paradigma interpretativo. Es una investigación de corte cualitativa enfocada al diseño fenomenológico. Se concluye en que el reto más significativo del trabajo desde casa es lograr la colaboración entre el padre de familia, alumno y docente.
Socialization of the Making of Hand Sanitizer and Instant Drinks from Herbs in Maintaining the Immune System for the Prevention of COVID 19
Authors: Dewi Citra , Fauziah Rismayanti , Lolok Nikeherpianti 
Published: February 2022

Corona Virus Disease of 2019 atau disebut COVID-19 merupakan wabah penyakit yang menginfeksi saluran pernafasan pada manusia yang dapat menyebabkan kematian. Wabah ini terjadi hampir di seluruh negara di Dunia. Upaya untuk mencegah penyebaran COVID-19 antara lain sering mencuci tangan atau menggunakan hand sanitizer dan meningkatkan sistem kekebalan tubuh (sistem imunitas) melalui asupan makanan yang kaya antioksidan maupun imun boost. Berdasarkan studi literatur yang telah dilakukan, tanaman lokal Indonesia diprediksi dapat menjadi kandidat penghambat COVID-19 seperti jahe (Zingiber officinale), kunyit (Curcuma longa L.), dan temulawak (Curcuma xanthorriza Roxb). Kegiatan pengabdian masyarakat ini melalui sosialisasi dilakukan di Desa Puasana, Kecamatan Moramo Utara, Kabupaten Konawe Selatan, Provinsi Sulawesi Tenggara. Tujuan sosialisasi ini adalah untuk memberikan edukasi dan mengajak masyarakat agar menjaga kesehatan dengan tetap menerapkan physical distancing dan meningkatkan sistem imun dengan mengkonsumsi makanan sehat serta menggunakan hand sanitizer pada saat keluar rumah. Metode pengabdian kepada masyarakat dilakukan dengan cara memberikan sosialisasi dengan media presentasi. Hasil dari pengabdian ini adalah meningkatnya pemahaman masyarakat khususnya di Desa Puasana tentang cara pembuatan hand sanitizer alami dan minuman herbal instan. Hal ini berdasarkan pada masyarakat yang aktif dan antusias dalam memberikan pertanyaan untuk mengetahui langkah-langkah pencegahan penyebaran Covid-19.

Kata kunci: Sosialisasi, Hand Sanitizer, Minuman Instan, Sistem Imun, COVID-19
Pesquisa de Staphylococcus spp. em queijos “Minas Frescal” feitos a partir de leite cru e comercializados no município de Formiga-MG
Authors: Campos João Victor Ferreira , Resende Luiza Camattari , Bastos Acácio Freire , Silva Mariana Oliveira , Acurcio Leonardo Borges 
Published: February 2022

O queijo “Minas Frescal”, de acordo com a legislação, é definido como o queijo fresco obtido por coagulação enzimática do leite com coalho e/ou outras enzimas coagulantes apropriadas, complementada ou não com ação de bactérias lácticas específicas. A legislação brasileira exige que estes sejam elaborados a partir de leites pasteurizados e proíbe a comercialização quando elaborados com leite cru pois, assim, podem ser importantes veículos de micro-organismos patogênicos. O objetivo deste trabalho foi analisar a presença de Staphylococcus spp. em queijos do tipo “Minas Frescal” elaborados de forma artesanal (com leite cru) e comercializados em mercados locais do município de Formiga – MG. O padrão microbiológico para este micro-organismo está definido em seu regulamento técnico de identidade e qualidade. O plaqueamento em Ágar Sal Manitol foi realizado em busca de Staphylococcus spp. e afim de diferenciar S. aureus de S. não aureus. Os resultados das amostras analisadas foram sugestivos para a presença de Staphylococcus aureus (104 to 106 UFC/g), ultrapassando os limites máximos permitidos estabelecidos (102 UFC/g). Pode-se concluir que os queijos não estavam aptos para consumo pela elevada contagem de Staphylococcus spp., que pode se dar pelo fato destes serem elaborados a partir de leite cru.
Dificuldades na aquisição de alimentos orgânicos em Unaí, Minas Gerais sob a percepção dos consumidores
Authors: Mendes Cardoso Leiriane , Campos Gevair 
Published: February 2022

O objetivo do presente trabalho foi identificar as dificuldades dos consumidores na aquisição de alimentos orgânicos da cidade de Unaí-MG . Os métodos utilizados para este trabalho foram através de uma pesquisa exploratória e também por amostragem não probabilística por conveniência estruturado em forma de formulário. Os resultados ilustram que as dificuldades encontradas pelos consumidores ao adquirir alimentos orgânicos em Unaí-MG, em primeiro lugar destaca-se o preço para 44% dos respondentes, seguido pela falta destes alimentos nos mercados para 38% dos respondentes, pois segundo os respondentes os alimentos são caros, e a falta nos mercados. Outro achado da pesquisa foi que os respondentes que incluiram alimentos orgânicos não só, tem uma alimentação mais saudável para 66% dos respondentes, mas também uma melhora na qualidade de vida, para 86% dos respondentes.
Pengaruh Penempatan dan Motivasi Kerja terhadap Kepuasan Kerja dan Kinerja Guru di Madrasah Aliyah Se-Kabupaten Jember
Authors: Rohim Nur , Umam Khotibul 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui pengaruh penempatan dan motivasi kerja terhadap kepuasan kerja dan kinerja guru di Madrasah Aliyah Se-Kabupaten Jember. Jumlah populasi 97 Madrasah dengan rincian tiga Madrasah Aliyah Negeri dan 94 Madrasah Aliyah Swasta. Jumlah sampel sebanyak enam madrasah dengan 100 responden. Teknik pengambilan sampel menggunakan purposive sampling. Metode penelitian menggunakan pendekatan kuantitatif jenisnya regresi. Pengumpulan data menggunakan teknik observasi, angket dan dokumen-dokumen. Analisis data menggunakan Path Analyisis. Data diolah dengan menggunakan program SPSS 16 for Windows. Penelitian sampai pada simpulan: Koefisien jalur pertama, penempatan berpengaruh positif dan signifikan terhadap kepuasan kerja guru serta kepuasan kerja guru juga berpengaruh positif dan signifikan terhadap kinerja guru. Jadi pengaruh langsung penempatan terhadap kinerja guru lebih efektif dari pada melalui kepuasan kerja. Koefisien jalur kedua, motivasi kerja berpengaruh tidak langsung terhadap kinerja guru. Akan tetapi motivasi berpengaruh positif dan signifikan terhadap kepuasan kerja. Jadi pengaruh motivasi kerja terhadap kinerja guru dapat melalui kepuasan kerja guru.
Kata Kunci: penempatan, motivasi kerja, kepuasan kerja, kinerja guru
This study aims to determine the effect of placement and work motivation on job satisfaction and teachers' performance in Madrasah Aliyah throughout Jember Regency. The total population is 97 madrasas consisting of three States and 94 private Madrasah Aliyahs. There are 100 research respondents incorporating six madrasahs in total. The sampling technique used was purposive sampling. This study used a regression type of quantitative approach. Data were collected through observation, questionnaires, and documentation, and then analyzed by using Path Analysis. The data were processed using SPSS 16 for Windows. Based on the results of the analysis and discussion, it can be concluded that; the first Path Coefficient, the placement, has a positive and significant effect on teachers' job satisfaction and the job satisfaction itself also has a positive and significant effect on teachers' performance. Hence, the direct effect of placement on teacher performance is more effective than job satisfaction. The second path coefficient, work motivation, has an indirect effect on teachers' performance. However, motivation has a positive and significant effect on job satisfaction. Therefore, the influence of work motivation on teachers' performance can be measured through teachers' job satisfaction.
Efektivitas Kompres Dingin Terhadap Skala Dismenorea Remaja Putri di SMAN 2 Ngaglik Sleman Yogyakarta
Authors: Wahyuningsih Melania 
Published: February 2022

Dismenorea disebabkan oleh ketidakseimbangan hormone progesterone darah yang mengakibatkan timbulnya nyeri saat menstuasi. Dismenorea bisa mengganggu aktivitas remaja putri. Cara menurunkan skala nyeri dismenorea yang murah dan efektif dengan kompres dingin. Penelitian ini quasi eksperimen pre dan post design, untuk mengetahui efektivitas kompres dingin terhadap skala dismenorea. Intervensi yang diberikan melakukan kompres dingin dengan air dingin 10-15 derajat Celcius selama 15 menit. Sampel penelitian 20 remaja putri yang mengalami menstruasi hari pertama. Teknik sampling yang digunakan quota sampling. Analisa data mengunakan Wilcoxcon test. Hasil penelitian median skala dismenorea sebelum kompres es, dan sesudah kompres es 5. Wilcoxon tes p value 0,001. Kompres dingin efektif untuk menurunkan skala dismenorea remaja putri di SMAN 2 Ngaglik Sleman Yogyakarta