bluuebunny/crossref_metadata_2025_split huggingface dataset:
Review: Uji Sterilitas dan Regionalisasi Laboratorium Sterilitas Badan POM
Authors: Setiawati Henny , Lolo Lukita Bertha 
Published: July 2022

Produk sediaan steril merupakan sediaan yang harus memenuhi persyaratan fisika, kimia serta harus memenuhi persyaratan bebas dari mikroorganisme baik bakteri maupun jamur. Uji sterilitas digunakan sebagai salah satu parameter untuk pelulusan produk dari pabrik, walaupun bukan untuk menjamin bahwa satu bets produk memenuhi syarat steril. Sediaan steril dibuat di fasilitas yang memiliki karakteristik lingkungan yang ketat untuk memperkecil risiko kontaminasi mikroba ke dalam produk. Pengujian produk steril juga memerlukan fasilitas ruangan tertentu atau isolator untuk menghindari terjadinya kontaminasi mikroba (hasil positif palsu), karena pengujian sterilitas hanya dapat dilakukan pengulangan pengujian jika terdapat kesalahan pada laboratorium penguji. Hasil uji sterilitas yang memberikan hasil tidak steril perlu direview apakah hasil yang diperoleh dihasilkan dari produk atau karena kesalahan laboratorium. Fasilitas atau instrumen pengujian yang mahal menyebabkan laboratorium uji sterilitas tidak dimiliki oleh semua Balai Besar/Balai POM saat ini. Regionalisasi laboratorium di Badan POM merupakan solusi untuk melakukan pengujian sterilitas yang memenuhi standar dan mengurangi biaya yang besar Ulasan ini dibuat berdasarkan studi literatur mencakup pengujian sterilitas berdasarkan pedoman nasional dan internasional, fasilitas pengujian sterilitas, kelemahan pengujian sterilitas serta investigasi hasil pengujian sterilitas. Ulasan ini juga akan memaparkan regionalisasi laboratorium uji sterilitas di Badan POM.
Preface: 2022 International Conference on Agriculture, Forestry and Economic Management (AFEM 2022)
Authors: Betsy Adonis , Zhang Jinkai 
Published: July 2022

2022 International Conference on Agriculture, Forestry and Economic Management (AFEM 2022) was held as a virtual event in Qingdao, China on May 28-29, 2022. The conference is a leading international conference for researchers and industry practitioners to share their new ideas, original research results and practical development experiences from agricultural science, forestry engineering, sustainable development, tourism management and economic management.
As coronavirus spreads worldwide, after careful consideration and following some participants' advices, the organizing committees decided to convert AFEM 2022 into a fully virtual conference. It has been a very difficult decision, but it has also given to all of us an opportunity to innovate and to test a new style of conference in a safer and convenient way in this special period. Researchers from all the world attended the conference from home and saw the live broadcast of the invited and contributed speeches.
The success of AFEM 2022 is due to the high scientific level of all the contributions as well as to the enthusiasm of all the attendees. The member of the technical committee did a precious job in selecting the papers that were accepted for presentation and for inclusion in this book of proceedings among those that were initially submitted. Beside the authors, participants, we would like to thank the members of the organizing committee, reviewers and volunteers, whose work was fundamental for assuring the smooth running of the conference.
We hope AFEM 2022 can develop into persistent success in future years, involving participants and speakers from all corners of the world. And we believe that with the strong support of all participants, professors, scholars, this conference will be more distinctive.
AFEM 2022 Conference Committee
Qingdao, China
Research on Importance Fluctuation of Stock Selection Factors Based on the Perspective of COVID-19 Epidemic Normalization
Authors: Shi Lei , Ai Yifei , Wang Ran 
Published: July 2022

Since the outbreak of COVID-19 epidemic, the efficiency of the Chinese A-share market has been severely decreased, so it is worthwhile for investors to set up a new stock selection system. This article proposes a novel factor quantitative method based on information entropy and Critic-weight for the Chinese A-share market before and after the normalization of epidemic. Then we use the combination machine learning method including Stochastic Forest, XGBoost, LightGBM, and mutual information to fit the stock return and evaluate factor importance. Under the condition that the model has stability and effectiveness, the results by using paired T-test method show that the impact of volatility factors on stock return is significantly enhanced, and the importance of factors such as scale and leverage is significantly descended.
Rancang Bangun Pot Pintar Berbasis IoT
Authors: Pratiwi Artdhita Fajar , Galih Mustiko Aji  , Arif Sumardiono  , Purwiyanto  , Sari Widya Utami  
Published: July 2022

Penelitian ini bertujuan untuk membuat pot pintar yang dapat memelihara tanaman hias dalam ruangan secara otomatis. Penelitian ini diawali dengan membuat desain model pot dalam gambar 3 dimensi dan difabrikasi menggunakan 3D printer. Pot terdiri dari 3 bagian yaitu bagian bawah untuk tempat penyimpanan kontroler, bagian tengah sebagai tempat air nutrisi dan bagian atas sebagai media tanam. Pot pintar dilengkapi sensor-sensor untuk mendukung pertumbuhan tanaman seperti sensor suhu dan kelembaban udara, soil moisture sensor dan sensor water level untuk kebutuhan nutrisi tanaman. Sistem ini dapat dimonitor dan dikendalikan melalui jarak jauh menggunakan smartphone android jika terhubung dengan wifi. Aplikasi android dibuat menggunakan MIT App Invetor yang dikoneksikan dengan database firebase agar dapat termonitoring melalui jaringan internet dari jarak jauh. Data-data sensor dikirimkan secara real-time dan tersimpan pada database firebase di dalam cloud. Hasil pengujian menunjukkan bahwa sensor-sensor di dalam pot mampu memberikan respon secara realtime selama proses pemeliharaan tanaman hias. Aplikasi android yang dibuat dapat menampilkan indikator dan status lingkungan mikro tanaman lebih detail daripada tampilan pada perangkat keras.
Challenges and Opportunities for use of Social Media in Higher Education
Authors: Anderson Terry 
Published: July 2022

Likely the most significant and life changing technologies of the 21st Century is the adoption of social media as major components of commercial, entertainment and educational activities. In this article, I overview the supposed benefits of the application of these tools within formal higher education programs. I then discuss the disadvantages and challenges, with a focus on the paradox that accompanies convenience and value in use, with loss of data control. It is likely that we will continue to see both authorized and unauthorized use of data that we have created for both personal and institutional use. I conclude by examining some of the solutions proposed and tested to resolve this challenge. I then overview two possible solutions - the first focused on institutions creating and managing their own social media and the second an emergent technical solution whereby users keep control of their data, while sharing and growing in multiple social contexts.
Gambaran Angka Kejadian Anemia Kehamilan Pada Kunjungan Pertama Berdasarkan Umur, Gravid, Paritas, Dan Riwayat Abortus Di Puskesmas Makale Pada Bulan Februari, Maret, Dan April Tahun 2017
Authors: Sampe Mariany 
Published: July 2022

Dampak anemia dapat menyebabkan berkurangnya daya konsentrasi, kemampuan akademik menurun, mudah merasa letih, jantung berdetak lebih cepat, warna kulit menjadi pucat, latergi, ganguan pada janin yang di kandung, menghambat pertumbuhan fisik, dampak menimbulkan resiko bayi lahir dengan berat badan yang kurang. Faktor yang menyebabkan terjadinya anemia adalah faktor lingkungan, perilaku, genetik, dan pelayanan kesehatan sendiri Penelitian ini bertujuan untuk mengetahui Gambaran Angka Kejadian Anemia Kehamilan Pada Kunjungan Pertama Berdasarkan Umur, Gravid, Paritas, Dan Riwayat Abortus Di Puskesmas Makale Pada Bulan Februari, Maret, Dan April Tahun 2017. Penelitian ini dilakukan di Puskesmas makale pada Tanggal 18 Januari 2018. Metode dalam penelitian ini adalah pengambilan data sekunder dan analisis deskriptif dengan menggunakan metode porpusive sampling yaitu sampel yang diambil berdasarkan karakteristik sesuai dengan ketentuan variabel independen ibu hamil yang memeriksa kehamilan pada kunjungan pertama (K.1) di Puskesmas Makale dengan jumlah 48 orang selama bulan Februari, Maret, dan April. dan namanya tercatat dalam buku register ANC. Dari hasil penelitian didapatkan 48 sampel yang tercatat dan ibu hamil yang anemia ada 29 orang (60,42%) dan yang tidak anemia ada 19 orang (39,58%). Dari kesimpulan diatas disarankan perlunya dukungan dari berbagai pihak yang terkait untuk mencari solusi dalam mencegah terjadinya anemia pada masa kehamilan
PELAKSANAAN PROGRAM TAKHASUS KITAB KUNING PONDOK PESANTREN MAMBA’UL KHAIRAT KETAPANG
Authors: Iwan Iwan 
Published: July 2022

Penelitian ini bertujuan untuk mengetahui mekanisme penerimaan, materi, metode, waktu, evaluasi, dan kendala dalam pelaksanaan program takhasus kitab kuning Pondok Pesantren Mamba’ul Khairat Ketapang.Penelitian ini menggunakan pendekatan kualitatif.Metode pengumpulan data dalam penelitian ini adalah; pengamatan, wawancara serta dokumentasi. Analisis data dilakukan melalui tiga tahapan, reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa pelaksanaan program takhasus kitab kuning di Pondok Pesantren Mamba’ul Khairat Ketapang adalah sebagai berikut 1) mekanisme penerimaan santri masuk takhasus adalah santri yang telah lancar dalam membaca Al-Qur’an, 2) materi yang disampaikan dalam pelaksanaan program takhasus meliputi materi nahwu, shorof, fiqih, tajwid, tafsir, tasawuf, hadits, tarikh, tauhid dan akhlak, 3) metode yang digunakan pada pelaksanaan program takhasus adalah metode sorogan, mudzakarah, hafalan, Tanya jawab dan memberi hadiah bagi santri yang aktif atau berprestasi, 4). Program takhasus membaca kitab kuning dimulai dari jam 14.00-16.30 WIB, 5) evaluasi pelaksanaan program takhasus membaca kitab kuning meliputi hasil belajar santri, materi yang disampaikan, metode yang digunakan, kebersihan, kedisiplinan, dan 6) Kendalayang dihadapi yaitu minimnya ruang kelas, media belajar dan alat peraga kemudian santri belajar tanpa kursi dan meja. Solusi yang akandilakukan: membangun ruang kelas yang memadai dan menyediakan kitab/buku penunjang, media belajar serta alat peraga.
LEARNING STYLES AND VARIETY OF MATERIALS IN ENGLISH TEACHING AND LEARNING
Authors: Fitriani Fitriani 
Published: July 2022

Applying of Learning styles and variety of materials are the important factors in teaching and learning English. When the teacher wants to teach must be prepare some materials and apply technic to get the students’ gaining. With recognizing about learning styles and variety of materials are very useful for language teachers to prepare and implement the effective and positive influence in teaching and learning English. Understanding the students’ learning style is the best way and technic to maximalise potential of students in learning process. After knowing the students’ learning style, the teacher will consider the best method to apply in the classroom. All students have not same their own learning style for understanding material in teaching and learning English. So the teacher can apply learning style the suitable condition their students and variant materials to get the students’ progress and avoid boring of class situation.
Taxonomic notes on the antlion tribe Myrmeleontini Latreille (Neuroptera, Myrmeleontidae, Myrmeleontinae) from Pakistan, with description of a new species
Authors: Hassan Muhammad Asghar , Zheng Yuchen , Liu Xingyue 
Published: July 2022

A new species of the myrmeleontine antlion genus Baliga Navás, 1912 (Neuroptera: Myrmeleontidae), Baliga kashmirensis sp. nov., from Azad Kashmir and Khyber Pakhtunkhwa Province of Pakistan is described and illustrated, representing the first record of Baliga from Pakistan. Three species of Myrmeleon Linnaeus, 1767 are re-described: M. hyalinus hyalinus Olivier, 1811, M. tenuipennis Rambur, 1842, and M. trivialis Gerstaecker, 1885. Myrmeleon bimaculatus Yang, 1999 syn. nov. originally described from China is considered to be a junior synonym of Myrmeleon tenuipennis Rambur, 1842. In addition, an annotated catalogue of all species of Myrmeleon known from Pakistan along with their distribution map, taxonomical notes and updated identification key to known genera and species are provided.
Nutritional Composition and Antioxidant Property of Methanol Extract of Corchorus olitorius Leaf
Authors: Okugbo O. T. , Braie A. , Komolafe V. T. , Amiebenomo R. 
Published: July 2022

Aims: This study investigates the phytochemicals, nutritional and antioxidant constituents of methanol extract of C. olitorius leaf using standard biochemical procedures.
Methodology: Corchorus olitorius (213.81 g) powdered leaves sample was soaked in 2.4 L of methanol respectively for 72 hr. Afterwards, the sample was filtered through a double-layered muslin cloth to obtain a filtrate which was placed in a rotary evaporator to dry off the solvent and stored. The proximate analysis, phytochemicals screening, mineral contents, antioxidant ability and phenolic compositions were determined for C. olitorius.
Results: The proximate analysis revealed that the C. olitorius extract contained 25.00% ash, 2.55% fat, 25.80% moisture, 5.50% crude fibre, 10.15% crude protein and 38.00% carbohydrate contents. Phytochemical screening indicated that flavonoids, tannins, cardiac glycosides, saponins, phenols and steroids were present in appreciable concentrations except for quinones and terpenoids. The mineral analysis of the extract showed considerable levels of potassium (1715.69 mg/100 g), calcium (33.43 mg/100 g), (sodium 49.62 mg/100 g), iron (16.78 mg/100 g) and manganese (9.44 mg/100 g) while magnesium (4.39 mg/100 g), copper (2.11 mg/100 g), zinc (2.94 mg/100 g) and lead (0.21 mg/100 g) were reduced. The extract showed high reducing power, diphenyl picrylhydrazine and H202 radicals scavenging abilities. However, the total antioxidant capacity was low compared to the standard, ascorbic acid. High performance liquid chromatography result revealed that quercitrin, quercetin, chlorogenic acid, syringic acid, epicatechin and kaempferol were present in high amounts in the extract.
Conclusion: Altogether, findings from this study indicated that C. olitorius leaf extract is a rich source of phytonutrients and mineral elements with ample antioxidative property (in vitro) that may be of relevance in the management of some degenerative conditions.
Evaluation of Traditional Know-How for the Cultivation of Muskuwaari Transplanted Sorghum in a Context of Climate Change (Mayo-Danay and Mayo-Kani, Far North Cameroon)
Authors: Nenwala Pa Aï Vivien , Tchobsala . , Delphine Dongock Nguemo , Moussa Saliou , Adamou Ibrahima , Bernard Danwang Djaowe , Oumar Oumar Mahamat 
Published: July 2022

Aims: Sorghum is a staple food crop and accounts for more than half of cereal production in the Far North region. It is ranked among the seven most important agricultural products in the CEMAC zone. Approximately 12% of this dry season sorghum, known as transplanted sorghum, is used extensively in the population's diet.
Study Design: The study conducted from 2017 to 2019 aims to assess the adopted techniques for better exploitation of Muskuwaari in the Far North region of Cameroon in a context where climate change has a strong influence on agricultural yield.
Methodology: The evaluation of Muskuwaari cultivation techniques is based on farmer surveys and direct field observations. A total of 390 people were surveyed in six different villages in the two regions.
Results: Cultivation lasts from July to April, for a period of 10 months. Several activities were identified: primary preparation of the field from July to August, setting up nurseries from August (This activity is poorly represented in Kalfou (16.92% on both types of soil) and in Kaélé (18.46% on clay soil and 13.85% on hydromorphic soil), preparation of the field from September (The most common techniques used today are spraying and transplanting (Technique 6): 34.92% in Guidiguis, 52.31% in Touloum, 50.77% in Kaélé, 62.50% in Kalfou, 35.38% in Doukoula, 55.38% in Tchatibali on average for the clay type soil and 40,63% in Guidiguis, 47.69% in Touloum, 56.92% in Kaélé, 52.46% in Kalfou, 47.62% in Doukoula, 46.77% in Tchatibali on average for the hydromorphic type soil), transplanting from September, weeding from November and harvesting from January. These activities vary according to the type of soil used and the villages.
Conclusion: The analysis of these Muskuwaari cultivation techniques showed a slight shift in relation to the cultivation calendar described in the past by other authors. This shift is caused by the change in climate that shortens and/or extends the rainy season from one year to the next.
Quality assurance and long‐term stability of a novel 3‐in‐1 X‐ray system for brachytherapy
Authors: Karius Andre , Szkitsak Juliane , Boronikolas Vasilios , Fietkau Rainer , Bert Christoph 
Published: July 2022

AbstractPurposeA novel, mobile 3‐in‐1 X‐ray system featuring radiography, fluoroscopy, and cone‐beam computed tomography (CBCT) has been launched for brachytherapy recently. Currently, there is no quality assurance (QA) procedure explicitly applicable to this system equipped with innovative technologies such as dynamic jaws and motorized lasers. We developed a dedicated QA procedure and, based on its performance for a duration of 6 months, provide an assessment of the device's stability over time.MethodsWith the developed QA procedure, we assessed the system's planar and CBCT‐imaging performance by investigating geometric accuracy, CT‐number stability, contrast‐noise‐ratio, uniformity, spatial resolution, low‐contrast detectability, dynamic range, and X‐ray exposure using dedicated phantoms. Furthermore, we evaluated geometric stability by using the flexmap‐approach and investigated the device's laser‐ and jaw‐positioning accuracy with an in‐house test phantom. CBCT‐ and planar‐imaging protocols for pelvis, breast, and abdomen imaging were examined.ResultsPlanar‐ and CBCT‐imaging performances were widely stable with a geometric accuracy ≤1 mm, CT‐number stability of up to 46 HU, and uniformity variations of up to 48 HU over time. For planar imaging, low‐contrast detectability and dynamic range exceeded current recommendations. Although geometric stability was considered tolerable, partly substantial positioning inaccuracies of up to more than 120 mm and −13 mm were obtained for lasers and jaws, respectively. X‐ray exposure showed small variations of ≤0.56 μGy and ≤0.76 mGy for planar‐ and CBCT‐imaging, respectively. The conductance of the QA procedure allowed a smooth evaluation of the system's overall performance.ConclusionWe developed a QA workflow for a novel 3‐in‐1 X‐ray system allowing to assess the device's imaging and hardware performance. The system showed in general a reasonable imaging performance and stability over time, whereas improvements regarding laser and jaw accuracy are strictly required.
Adaptive fixed‐time fuzzy control for output constrained nonlinear systems with unknown virtual control coefficients based on event‐triggered mechanism
Authors: Liu Mengru , Zhang Weihai 
Published: July 2022

SummaryThe paper discusses a fixed‐time fuzzy adaptive event‐triggered control for the nonlinear systems with output constraint and unknown virtual control coefficients. Fuzzy logic systems are utilized to approximate the uncertain nonlinearities. The barrier Lyapunov function is employed to analyze the stability and avoid violating the given output constraint. The combination of the designed adaptive laws and fixed‐time control signal is used to reduce restriction on unknown virtual control coefficients and increase the robustness for control. An event‐triggered mechanism is proposed to update controllers to save communication resources. The control strategy makes sure that the tracking error can converge into a small neighborhood of the origin in a fixed time. Finally, the efficacy of the proposed control approach is verified by two simulation examples.
Excited State Properties of Aggregation‐Induced Delayed Fluorescence Molecules: A Microscopic Insight
Authors: Lu Xueying , Hu Yongxu , Liu Huapeng , Qi Jiannan , Chen Xiaosong , Sun Yajing , Hu Wenping 
Published: July 2022

AbstractPurely organic fluorescence emitters with ultrahigh exciton utilization, such as thermally‐activated delayed fluorescence (TADF) materials, are pursued as the cornerstone of the new‐generation organic light‐emitting diodes (OLEDs). However, most TADF emitters suffer from the dilemma of the aggregation‐caused fluorescence quenching effects, severely limiting their applications. Excitingly, the recently proposed aggregation‐induced delayed fluorescence (AIDF) strategy holds the potential to tackle this problem thoroughly. Here, the recently reported AIDF emitters CP‐BP‐PXZ and its halogenated counterparts, 3‐CCP‐BP‐PXZ and 3‐BCP‐BP‐PXZ, are investigated with a united theoretical and experimental insight. Based on first‐principles calculations combined with the polarizable continuum model (PCM) and the quantum mechanics/molecular mechanics (QM/MM) model, the photophysical mechanisms of these novel materials are proposed. It is found that both reverse intersystem crossing (RISC) and the subsequent radiative transition of CP‐BP‐PXZ are promoted via aggregation, owing to the increased effective RISC channels and boosted oscillator strength. Meanwhile, the unfavorable internal conversion rate is greatly slumped, ascribed to the suppressed Duschinsky rotation effect (DRE). The unique heavy‐atom effect is disclosed in 3‐CCP‐BP‐PXZ and 3‐BCP‐BP‐PXZ that the halogens act as steric blockers in crystal, rather than spin–orbit coupling enhancers. It is hoped that this work can shed new light on the designation of high‐efficient solid‐state fluorescence emitters.
A Uterus‐Inspired Niche Drives Blastocyst Development to the Early Organogenesis
Authors: Gu Zhen , Guo Jia , Zhai Jinglei , Feng Guihai , Wang Xianning , Gao Zili , Li Kai , Ji Shen , Wang Leyun , Xu Yanhong , Chen Xi , Wang Yiming , Guo Shanshan , Yang Man , Li Linlin , Han Hua , Jiang Liyuan , Wen Yongqiang , Wang Liu , Hao Jie , Li Wei , Wang Shutao , Wang Hongmei , Gu Qi 
Published: July 2022

AbstractThe fundamental physical features such as the mechanical properties and microstructures of the uterus need to be considered when building in vitro culture platforms to mimic the uterus for embryo implantation and further development but have long been neglected. Here, a uterus‐inspired niche (UN) constructed by grafting collagen gels onto polydimethylsiloxane based on a systematic investigation of a series of parameters (varying concentrations and thicknesses of collagen gel) is established to intrinsically specify and simulate the mechanics and microstructures of the mouse uterus. This brand‐new and unique system is robust in supporting embryo invasion, as evidenced by the special interaction between the embryos and the UN system and successfully promoting E3.5 embryo development into the early organogenesis stage. This platform serves as a powerful tool for developmental biology and tissue engineering.