bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical study of branch retinal vein occlusion (BRVO) in a tertiary eye care center
Authors: Swain Suresh Chandra , Parida Subhabrata , Sethy Shubham 
Published: November 2022

Branch Retinal Vein Occlusion (BRVO) is a common retinal vascular disorder which involves one of the branch retinal veins. The aim of the study is to analyse epidemiology, risk factors, clinical characteristics in the distribution of different types of BRVO and final visual outcome after treatment and six months follow up. This is a prospective study including 222 patients of BRVO was done from October-2018 to September-2020. Clinical evalution included, detailed history with systemic risk factors, visual acuity testing, Slit-lamp biomicroscopy, Intra occular pressure, detailed fundus evaluation, fundus fluorescein angiography, Optical Coherence Tomography and Gonioscopy. Laboratory test included complete blood count, Erythrocyte sedimention rate, fasting blood sugar, serum lipid profile. Treatment given, observation and follow up, intravitreal (lV) ranibizumab, IV triamcinolone and laser photo coagulation. Out of 222 BRVO patients, 207 (94.1%) were major BRVO (129(58.1%) were suprotemporal BRVO, 66(29.8%) were inferotemporal BRVO) and 15 (5.9%) were macular BRVO. Maximum number of patients 108 (48.6%) in the age group of 61-70 years. Male patients 126 (56.7%) more than females 96 (43.3%). Right eye 117 cases (52.7%) were involved slight more than the left eye 102 cases (45.9%). Blurring of vision 162 (72.9%) is the commonest symptom. Hypertensive patients 113 (50.9%) affected more followed by Diabetic 36 (16.2%) and cardiovascular disease 33 (14.9%). Mean Systolic blood pressure (SBP), Diastolic blood pressure (DBP), ESR & Fasting blood sugar (FBS) are higher in Macular BRVO, cholesterol level is higher in Major BRVO. Retinal haemorrhage was present in all cases. Macular edema was present in 87.4% of patients in whom OCT was done. At the end of six months after treatment in majority of patients i:e 85.1% had BCVA between 6/6-6/18. There was dramatical improvement of vision after receiving intravitreal Ranibizumab (P value 0.041).There is strong association of conventional risk factors with BRVO. Visual prognosis depends on initial status with careful monitoring for macular ischaemia, macular edema, development of neovascularization and subsequent neovascular glaucoma followed by appropriate therapy like IV Ranibizumab, IV Triamcinolone and laser photocoagulation etc wherever required. There is dramatical improvement of vision after receiving intravitreal Ranibizumab (P value 0.041).
Covid 19 pandemic-lockdown and its psychological effects on children age group 4 to 10 years, a cross-sectional study from a school in Central India
Authors: Pazare Pradeep , Bansode Swapnali , Khobragade Roopal 
Published: November 2022

This study will provide an insight into the psychological impact of lockdown on young children. The current study is a questionnaire-based cross-sectional study. The research was done among parents of children ranging in age from 4 to 10 years old who attend various schools in Nagpur city. The research ran from March 2021 to August 2021, for a total of six months. The study enlisted the participation of parents of kids aged 4 to 10 years old. Sadness significant, found that children of both working parents are significantly sad as compared to non-working or only any 1 parent working (p= o.008). Also, children who are using smartphones for &#60;2hours for playing games are significantly sad than others. (p=0.001). Aggressiveness was significantly (p= 0.002). Children of &#60;7 years are significantly more aggressive than &#62;7years. Anxiety was significantly more among females compared to male children (p=0.03). Also, children belonging to single parents and joint families were significantly more anxious compared to nuclear families (p=0.04).The lockdown due to the Covid-19 pandemic has caused profound psychological effects and has increased the rates of depression, anxiety, sadness, and aggressiveness in children.
Hubungan Asupan Makronutrien, Aktivitas Fisik, dan Status Gizi dengan Usia Menarche Pada Remaja Perempuan Usia 9-15 Tahun di Desa Kedunglosari Kabupaten Jombang
Authors: Tri Sutanti Puji Hartati  , Farapti Farapti  , Emyr Reisha Isaura  
Published: November 2022

Background: Menarche is the first menstruation experienced by adolescent girls. The age of menarche in Indonesia has decreased from 13 years in 2010 to 12.4 years in 2018. The age of menarche is influenced by internal and external factors, some of the factors are macronutrient intake, physical activity, and nutritional status. The decrease in age at menarche is associated with an increased likelihood of uterine myoma, dysmenorrhea, and breast cancer.
Objectives: To analyze the relationship between macronutrient intake, physical activity, nutritional status and age at menarche in adolescents Girl 9-15 years old.
Methods: This research used cross sectional design with sample size of 87 adolescent girls who had experienced menstruation and selected using simple random sampling. Data were collected by macronutrient intake used Semi-Food Frequency Questionnaire (SQFFQ), physical activity used Short Form International Physical Activity Questionnaire (SF-IPAQ), anthropometric data to assess nutritional status through measurement of body weight and height and age of menarche used a self-report questionnaire. Data was analyzed by t-test, chi-square and linear regression with 95% confidence level.
Result: There was a significant relationship between fat intake (­p = 0,049) and nutritional status (β = -0.92, p <0.001) with the age of menarche. The results of the analysis showed that there was no significant relationship between energy intake (p = 0,058), protein intake (p = 0,178), carbohydrate intake (p = 0,099), and physical activity (p = 0,422) with age at menarche.
Conclusions: fat intake and nutritional status during adolescence is related to the age of menarche. Prevention for cancer in women should be carried out as early as possible when adolescent girls have not menarche. One of prevention is managing the nutritional status of adolescent girls by paying attention to diet.
Keywords: nutritional status, macronutrient intake, physical activity, age at menarche, adolescent girls
Aplikasi Penggunaan Alat Pengering Pengganti Oven untuk Pembuatan Herbarium di Kebun Raya Liwa Kabupaten Lampung Barat
Authors: Yulianty  , Amir supriyanto  , Eti Ernawiati  , Lili Chrisnawati  
Published: November 2022

One of the countries with high biodiversity is Indonesia. The potential of existing plants has not been maximally empowered by the community, especially in the Liwa Botanical Gardens. The involvement of the staff in the KRL is very necessary to be able to directly collect the observed plants and make a herbarium. Constraint faced in making herbarium is in the drying process. So far, the herbarium drying process is still being carried out in Department of Biology, University of Lampung. This PKM activity will begin with a pre-test to determine the initial ability of KRL staff on the importance of the drying process and the practice of making simple herbarium dryers instead of ovens. At the end of the activity, KRL staff were given a post-test to determine the increase in knowledge about the importance of drying herbariums. With this PKM activity, KRL staff increase their knowledge and skills in using simple tools for drying plant samples and in the long term the availability of more diverse herbariums in an effort to conserve potential plants in KRL. The result of this activity was an increase in score points by 28.08 and a percentage increase in knowledge of 51.63%.
Industrial Organization of the Maritime Seismic Acquisition Market
Authors: Junior Paulo Roberto de Melo Barros , Ferreira Hamilton , Lemos Mauro 
Published: November 2022

Abstract
In this article, we analyze the industrial organization of the Maritime Seismic Acquisition Market (MSAM). Firms in this market are process, science, and technology-intensive and provide critical geophysical information for oil companies operating in the upstream offshore segment. We aim to find the determinants of price and cost changes and their relationships with market structures, firms conduct, and performance (SCP), considering the effect of oil price volatility on MSAM demand. To achieve this objective, we use a theoretical framework of Industrial Organization (IO) to analyze the empirical data of MSAM at a global database between 2006 and 2019. Our work is structured to estimate SCP and the New Empirical IO (NEIO) parameters related to concentration, market power, and competition and verify the hypothesis about market power or collusion from empirical demand and cost models. We found that concentration levels and profits in MSAM firms decrease to any demand increase. These concentration and profit fluctuations occur because market-fringe firms generate competitive pressure on the industry's average costs, an essential factor explaining price increases during market heating periods. Although MSAM has a sizeable concentration level, its firms have low levels of market power and markups with a high degree of competition, which is typical of a Competitive Oligopoly.
Relationship between Internet Addiction and Obesity and the Predictive Role of Emotion Dysregulation
Authors: Azizi Morteza , Abbasi Behrouz , Aghaei Hajar 
Published: November 2022

Abstract
Background: In recent decades, with the significant developments in technology, the Internet has become a main part of peoples' lives. The widespread use of the Internet has raised significant concerns about problematic Internet behaviors and their consequences. This study aimed to examine if Internet addiction significantly predicts obesity and whether Internet addiction and obesity are significantly predicted by emotion dysregulation.
Mthods: 367 school-attending adolescents (M age = 13.35; SD = 0.82; 49% girls) in Tekab were recruited and completed the Difficulties in Emotion Regulation Scale (DERS) and Internet Addiction Test (IAT) measures, while their BMI scores were calculated to examine the participants' obesity levels.
Results: The results indicated that Internet addiction significantly predicted obesity, while they both were significantly predicted by emotion dysregulations.
Conclusion: Our findings could be informative for clinicians working with individuals suffering from Internet addiction and obesity.
Differences in the Seoi-Nage Skill between Eite and Non-Elite Judo Players
Authors: Choi Sang-Hyup , Song Yong-Gwan 
Published: November 2022

Abstract
Seoi-nage skill is one of the most frequently used skills in judo matches and comprises three phases, namely unbalancing, positioning, and throwing. It is necessary to understand the kinematic characteristics of the three phases to provide helpful feedback for learning and guiding seoi-nage skills. We aimed to investigate the kinematics of each phase using a judo throw device and a three-dimensional motion capture camera system. On comparing the performances of elite and amateur (non-elite) judo players (10 each), the rotation and tilt angle characteristics of the shoulder, pelvis, and hip and knee joint flexion-extension angle were better in the elite group. Our findings indicate that kinematic variables determine the effective performance of seoi-nage. The center of gravity of the opponent gets lifted (unbalancing), following which the body moves forward to the opponent (positioning). It must pull the opponent to the end such that they can throw it down (throw). While the rate of change in the vertical direction should be significant, that in the horizontal direction should be low to pull the opponent sufficiently toward the attacker’s body. In addition, the shoulder and pelvis should be rotated together while maintaining the extension of the hip and knee joints to achieve effective sedation.
Analysis of georadar responses on environmentally significant karst landform
Authors: Gao Qiangshan , Hussain Yawar , Yang Tianchun 
Published: November 2022

Abstract
Peak-cluster depression (PCD) is a typical karst landform and a crucial aspect in non-invasive geophysical evaluation of the environmental concerns of the karst desertification regions (i.e., canopy growths, animal habitat, among others) related with karstification and its soil stocks and their moisture contents. To that end, a promising non-invasion, less labour-intensive and cost-prohibited geophysical technique (georadar/GPR) being limited in its operations because of the tilt signals and loss of information introduced by the uneven topography of PCD. Therefore, it requires a detailed investigation applying numerical analysis (considering karst topography and soil conductivity) implicating in a case study which is the scope of the present work. The findings of numerical analysis showed that under moderate soil conductivity conditions, the tilt signals could contain the reflections from both surrounding hills and subsurface inclined interfaces. The data processing workflows include the F-K filtering to remove or suppress the tilt signals. Then we applied the attribute analysis as additional information to aid in interpreting soil depth in depression. The soil depth obtained from the auger showed results highly consistent with that of the GPR findings. It is concluded that the application potential of GPR for the karst peak-cluster depression study is moderate to the fact that inferred information can partly be utilised while the rest is mixed or contaminated with other irrelevant information.
An Online and Highly-Scalable Streaming Platform for Filtering Trolls with Transfer Learning
Authors: Lai Chun-Ming , Chang Ting-Wei , Yang Chao-Tung 
Published: November 2022

Abstract
Society nowadays is provided with a maturely developed internet, and On-line Social Media (OSM) such as Twitter and Facebook are one of the vital communication channels for information exchange and public affairs discussion. Unfortunately , due to anonymity and trolls, improper statement or content are corroding these OSM platforms and their users. Current defense methods for inappropriate information are based on offline (semi)-manual assessments and fail to take into account that OSM feeds are online data streams. In this paper, we implement a robust and decoupled system considering social media data as streaming data. With Publisher and Consumer model, our system can process more than 179 MB per second with only 166.3 ms latency using Apache Kafka. Accordingly, we deploy a well-trained transfer learning model to classify incoming data streams with an accuracy of 0.836. It’s our hope that the proposed architecture can help the community to build a more constructive and flawless OSM platforms.
Some Immunological characters in Women with Celiac Disease from Thi-Qar province - South of Iraq
Authors: Abdullah Safaa Hussein , Al-Badran Adnan Issa 
Published: November 2022

Abstract
Background
Celiac disease is a chronic small intestinal inflammatory disease characterized by a lifelong reaction to dietary gluten in individuals with genetic predisposed. Many studies were suggests the presence of celiac disease predominance in woman than man patients. This study was conducted in Thi-Qar province and the blood samples were collected from healthy and celiac patients whose diagnosed by serology tests using Enzyme Linkage Immuno Sorbent Assay. The current study was designed to demonstrate women's serologic parameters and their characters in Thi-Qar province.
Results
This case-control study demonstrates that women are predominance to incidence with celiac disease and the Anti-tissue transglutaminase IgG is the best and quite accurate test than other tests used in diagnostic approach.
Conclusions
This study detects that women are more susceptible to incidence with CD and using the two steps testing is a quite precise strategy for the diagnosis of suspicious persons and can be a potent marker for monitoring the activity of celiac disease.
An Expectation-Maximization approach for matrix factorization in location-based recommender systems
Authors: Moayedikia Alireza 
Published: November 2022

Abstract
On Location Based Social Network (LBSN) platforms, users benefit from location recommendation algorithms to find places of interest. Several algorithms have been proposed to accomplish the location recommendation task. However, these algorithms suffer from (i) the lack of trust information consideration and (ii) assuming users’ interest are static and does not change overtime. To overcome these two shortcomings this paper introduces an adaptive probabilistic-based location recommendation algorithm known as EXMAX which uses expectation-maximisation along with matrix factorisation to predict the rating a user may give to the next visit. The predicted rating will be used as a filter to remove any places with a score lower than the user’s predicted rating. EXMAX represents check-in data as a user-location matrix where every time a user checks into a new location check-in along with location information will be appended to the user-location matrix. This representation method ensures EXMAX preserves the most up-to-date users’ preference information. Also, the proposed algorithm exploits friendship network data as well as sentiment of the comments left by the user to label every checkin with either a positive or negative experience. To measure EXMAX efficacy, its performance is tested in several experimentation scenarios and compared against three rival algorithms in terms of root mean square error and Yelp dataset. The results confirm EXMAX robustness and superiority over other probabilistic and statistic location recommendation algorithms.
Identification of Potent and Novel Inhibitors against Dual specificity mitogen-activated protein kinase kinase 1 (MEK1)
Authors: Madhukar Geet , Kumari Sangeeta , Rath Pragyan Parimita , Gourinath Samudrala , Mondal Neelima , Subbarao Naidu 
Published: November 2022

Abstract
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer, globally. Its high mortality rates hasn’t changed much in the last three decades and the overall survival is still less than 5 years. Therefore, there is an urgent need for novel therapeutics specifically developed for HNSCC. One of the most commonly altered oncogenic pathways is Ras-Raf-MEK-ERK signalling pathway. This pathway is downstream to EGFR and has been reported to be involved in radio resistance. MEK1 is a tyrosine/threonine protein kinase found in the MAP kinase (MAPK) signalling cascade which is constitutively expressed in approximately 30% of all the cancer types. It holds a very strategic position in the MAPK cascade. It is the only kinase which activates ERK ½ which is involved in several cellular pathways, both cytoplasmic as well as nuclear and has been found mutated in various cancers including HNSCC. Currently, there is no FDA approved inhibitor of MEK1 specifically against HNSCC. Therefore, designing more effective and specific MEK1 inhibitors could be a promising strategy in the treatment of HNSCC. We screened more than 400,000 compounds to select the two best candidate compounds, C387-1559 and G545-0469 using High Throughput Screening (HTS) of huge databases (National Cancer Institute (NCI), Life Chemicals, Chem Diversity and ChEMBL), and Molecular Dynamic Simulations. Both the selected compounds were further analysed at different concentrations by Biolayer Interferometry (BLI) technique for their real-time interaction with the MEK1 protein. The selected compounds were evaluated for their cytotoxic effect against different cancer cell lines. The IC50 values of the compounds C387-1559 and G545-0469 on human tongue squamous cell carcinoma cell line, CAL27, were 5µM and 6µM, respectively and on human prostate cancer cell line, DU145, were 14.77 µM, 54.38 µM, respectively at 72hrs. This data suggests higher efficiency of C387-1559 and G545-0469 on human head and neck squamous cell cancer than human prostate cancer. Overall, this study identified two novel inhibitors of MEK1 that can be used in the development of potential therapeutics against HNSCC.
Investigation on reachable domain of contingency return trajectories in the circumlunar flight phase based on interval analysis
Authors: Lu Lin , Zhou Jianping , Li Haiyang , Zhang Hailian 
Published: November 2022

Abstract
The investigation on reachable domain based on interval analysis is performed, which is aimed for the contingency return trajectories during the circumlunar flight stage for manned lunar landing engineering. First, the issue of contingency return trajectory which adopts a non-coplanar maneuver during the circumlunar flight phase is described. The mathematics model of the reachable domain of contingency return trajectories is established. Second, the contingency return trajectory is designed. An improved interval branch and bound algorithm is introduced and a reachable domain calculation method of the contingency return trajectories is proposed. Third, in numerical simulations, by comparing the reachable domain obtained by the traditional brute force method, the accuracy of the method presented in this paper is verified. It also indicates that this method has a higher calculation efficiency. Finally, abundant simulations are performed to discuss the parameter characteristic of reachable domain by adopting this method. The study conclusions can serve as an important reference for the selection and decision of contingency return trajectory plans in the future manned lunar landing engineering.