bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of the AI-Cirrhosis-ECG Score: An Electrocardiogram-Based Deep Learning Model in Cirrhosis
Authors: Ahn Joseph C. , Attia Zachi I. , Rattan Puru , Mullan Aidan F. , Buryska Seth , Allen Alina M. , Kamath Patrick S. , Friedman Paul A. , Shah Vijay H. , Noseworthy Peter A. , Simonetto Douglas A. 
Published: January 2022

INTRODUCTION:
Cirrhosis is associated with cardiac dysfunction and distinct electrocardiogram (ECG) abnormalities. This study aimed to develop a proof-of-concept deep learning-based artificial intelligence (AI) model that could detect cirrhosis-related signals on ECG and generate an AI-Cirrhosis-ECG (ACE) score that would correlate with disease severity.

METHODS:
A review of Mayo Clinic's electronic health records identified 5,212 patients with advanced cirrhosis ≥18 years who underwent liver transplantation at the 3 Mayo Clinic transplant centers between 1988 and 2019. The patients were matched by age and sex in a 1:4 ratio to controls without liver disease and then divided into training, validation, and test sets using a 70%-10%-20% split. The primary outcome was the performance of the model in distinguishing patients with cirrhosis from controls using their ECGs. In addition, the association between the ACE score and the severity of patients' liver disease was assessed.

RESULTS:
The model's area under the curve in the test set was 0.908 with 84.9% sensitivity and 83.2% specificity, and this performance remained consistent after additional matching for medical comorbidities. Significant elevations in the ACE scores were seen with increasing model for end-stage liver disease-sodium score. Longitudinal trends in the ACE scores before and after liver transplantation mirrored the progression and resolution of liver disease.

DISCUSSION:
The ACE score, a deep learning model, can accurately discriminate ECGs from patients with and without cirrhosis. This novel relationship between AI-enabled ECG analysis and cirrhosis holds promise as the basis for future low-cost tools and applications in the care of patients with liver disease.
A blending of Buddhism, social engagement, and alternative agriculture from Thailand: the Maap Euang Meditation Center for Sufficiency Economy
Authors: Schertenleib Dimitri 
Published: January 2022

Abstract
Today, across all the places where the various Buddhist schools have established themselves, there is a broad phenomenon with heterogeneous characteristics and manifestations called engaged Buddhism or socially engaged Buddhism. What unites the advocates of this movement is the way the Buddhist notion of dukkha (i.e., ‘suffering’) is interpreted to include the economic, political, social, and even ecological dimensions of suffering in the contemporary world. Engaged Buddhists have reformulated the normative teachings of dukkha to make them relevant to current issues. In this paper, I present an example of ecologically and socially engaged Theravāda Buddhism of the Maap Euang Meditation Center for Sufficiency Economy, in Thailand near Bangkok. Members of this community have developed a form of engaged Buddhism that treats ideas of “sufficiency” economy and peasant agroecology. To understand this movement, I will argue that the discipline of Buddhist Studies needs to combine the study of ancient canonical texts with the study of their contemporary interpretations.
Performance analysis of long band passive optical network using amplifier spontaneous noise and fiber Bragg gratings
Authors: Mohal Ranbir Singh , Kaur Rajbir , Singh Charanjit 
Published: January 2022

Abstract
Long band (L-Band) passive optical networks (PONs) are attracting a lot of attention these days, thanks to rising capacity demands. Because of PONs requesting more and more channels, fault detection/monitoring is critical. Fault detection in the conventional band (C-Band) employing reflecting Fiber Bragg Gratings (FBGs) and a probe signal integrating an additional amplified spontaneous noise (ASEN) source has been frequently demonstrated. However, interference occurs when ASEN and transmitter signals are in the same wavelength band, and adding additional ASEN sources to the network raises the overall cost. So, in L-Band PONs, a cost-effective, low-complexity fault detection/monitoring system is required. Therefore, in this work, a fault detection/monitoring system for L-Band PON using C-Band ASEN from inline erbium doped fiber amplifier (EDFA) and dual purpose FBG, i.e. (1) ASEN reflection for fault monitoring and (2) dispersion compensation is proposed. A 4 × 10 Gbps L-Band PON is investigated over 40 km feeder fiber (FF) and 1 km drop fibers (DFs) that serve 32 optical network units (ONUs)/different input powers, dispersion values, and laser linewidths in terms of reflective power of FBGs, eye opening factor, and bit error rate (BER), respectively.
Role of the SARS-CoV-2 virus in the appearance of new onset type 1 diabetes mellitus in children in Gran Canaria, Spain
Authors: Nóvoa-Medina Yeray , Pavlovic-Nesic Svetlana , González-Martín Jesús Ma , Hernández-Betancor Araceli , López Sara , Domínguez-García Angela , Quinteiro-Domínguez Sofía , Cabrera María , De La Cuesta Araceli , Caballero-Fernández Elisabeth , González-Perera María A. , De Miguel-Martínez Isabel , Ogle Graham D. , Wägner Ana M. 
Published: January 2022

Abstract

Objectives
It has been hypothesized that SARS-CoV-2 may play a role in the development of different forms of diabetes mellitus (DM). The Canary Islands have the highest incidence of type 1 DM (T1DM) reported in Spain (30–35/100,000 children under 14 years/year). In 2020–2021 we observed the highest incidence so far on the island of Gran Canaria, as a result of which we decided to evaluate the possible role of COVID-19 in the increased number of onsets.

Methods
We examined the presence of IgG antibodies against SARS-CoV-2 in children with new onset T1DM between October 2020 and August 2021. We compared recent T1DM incidence with that of the previous 10 years.

Results
Forty-two patients were diagnosed with T1DM (48.1/100,000 patients/year), representing a nonsignificant 25.7% increase from the expected incidence. Of the 33 patients who consented to the study, 32 presented negative IgG values, with only one patient reflecting undiagnosed past infection. Forty-four percent of patients presented with ketoacidosis at onset, which was similar to previous years.

Conclusions
We conclude that there is no direct relationship between the increased incidence of T1DM and SARS-CoV-2 in the region. The COVID-19 pandemic did not result in an increased severity of T1DM presentation.
Bayesian Analysis of State Voter Registration Database Integrity
Authors: Cao Jian , Kim Seo-young Silvia , Alvarez R. Michael 
Published: January 2022

Abstract
How do we ensure a statewide voter registration database’s accuracy and integrity, especially when the database depends on aggregating decentralized, sub-state data with different list maintenance practices? We develop a Bayesian multivariate multilevel model to account for correlated patterns of change over time in multiple response variables, and label statewide anomalies using deviations from model predictions. We apply our model to California’s 22 million registered voters, using 25 snapshots from the 2020 presidential election. We estimate countywide change rates for multiple response variables such as changes in voter’s partisan affiliation and jointly model these changes. The model outperforms a simple interquartile range (IQR) detection when tested with synthetic data. This is a proof-of-concept that demonstrates the utility of the Bayesian methodology, as despite the heterogeneity in list maintenance practices, a principled, statistical approach is useful. At the county level, the total numbers of anomalies are positively correlated with the average election cost per registered voter between 2017 and 2019. Given the recent efforts to modernize and secure voter list maintenance procedures in the For the People Act of 2021, we argue that checking whether counties or municipalities are behaving similarly at the state level is also an essential step in ensuring electoral integrity.
Development and quality characteristics of sugar and fat free muffins utilising stevia and chia mucilage
Authors: Gökşen G. , Bakachan Ç. , Ekiz H.I. 
Published: January 2022

AbstractCake is a popular bakery product consumed by almost everyone due to its low economic cost and shelflife, however, it is recognised unhealthy because of high fat and sugar contents. The aim of this study was to evaluate physicochemical and sensory properties of muffins baked using 100% of sugar and fat replacement as stevia sweetener (rebaudioside A and erythritol) and chia seed mucilage, respectively. The combination of sweetener with chia gel (SCC) had the highest moisture content, while the replacement of fat in muffin (CC) revealed similarity to the control in lightness and redness values. There was also no significant difference in terms of firmness when only the sweetener was replaced (SC). While the control muffin obtained the highest overall acceptability score, the lowest score was observed in CC. Thus, muffins with reduced fat and sugar contents can benefit the consumer in terms of health, but further optimisation of formulations for both replacers is needed for better sensory acceptance.
The Implementation of Trauma Healing to The Bullying at Rumah Duta Revolusi Mental Semarang
Authors: Kibtyah Maryatul , Rohmah Ana Mawadda , Maulana Khabib Akbar 
Published: January 2022

This research describes the implementation of trauma healing to victims of bullying at the Rumah Duta Revolusi Mental in Semarang City using Islamic Counseling Guidance. The collecting data technique were interviews, observation, and documentation. Furthermore, the data analysis technique used the Milles and Huberman model, namely: data reduction, data presentation, and data verification. The results showed that the implementation of trauma healing to victims of bullying at the Rumah Duta Revolusi Mental in Semarang City had two forms of programs, namely counseling and psychotherapy including several therapies, namely play therapy, emotional catharsis, fairy tale therapy, and, writing therapy. Meanwhile, trauma healing is carried out through three stages, namely the initial stage, the middle stage or the work stage, and the final stage or the termination stage. Judging the Islamic Counseling Guidance, both in terms of the objectives, functions, and methods of trauma healing to the victims was an implementation of the techniques, stages, methods of trauma healing.
The Effect of the Use of Instagram Social Media on the Effectiveness of Da'wa Messages on the @gusmiftah Account among Teenagers
Authors: Chairiyah Ummy , Achmad Fandi , Arida Vera , Falasifah Nihlatul 
Published: January 2022

Social media is not only used to find information but also as a means of conveying religious teachings. Many cleric use social media to spread Islam. Currently, da'wah is packaged neatly, creatively, and innovatively without reducing the message conveyed. This research is entitled The Effect of Instagram Social Media on the Effectiveness of Da'wa Messages. This study aims to determine how much influence the use of social media Instagram has on the effectiveness of da'wa messages. This type of research is quantitative research and the instrument used is a questionnaire. Using the theory of mass communication effects and simple regression test in the data analysis technique. The validity of the data is obtained through validity and reliability. Based on the results of the simple regression test that has been carried out in this study, the value of r = 0,829 and has a coefficient of determination of 75,9%. This shows that there is a positive and very strong relationship between the effect of using social media on the effectiveness of da'wah by 75,9%.
Keywords: social media, Instagram, effectiveness, da'wa.
Effects of Different Phosphorus Fertilizer Levels on Growth and Yield Components of Chickpea (Cicer-arietinum L.)
Authors: Maaruf Karwan , Saeed Nask , Tahir Nawroz 
Published: January 2022

From the winter seasons 2018-2019 and 2019-2020, a field experiment was conducted at the Directorate of Agricultural Research Sulaimani in the Kurdistan province of Iraq to evaluate the various levels of phosphorus control, 25, 50, 75, and 100 P2O5 kg ha-1 as triple superphosphate on the growth and yield components of chickpea (Cicer arietinum L.) by using a randomized complete block design (RCBD). Based on a statistical analysis of variance conducted over the two years the influence of various phosphorus analyses had no significant effects on the plant height, number of branches per plant and protein content. Whereas, in both years, the effect of different phosphorus levels application had a significant effect on the number of pods per plant, the number of grains per plant, 100-grain of weight, gains of weight, and grain yield. According to best output, the results showed that 100 P2O5 kg ha-1 had the best positive effect during the two-year study.
Incidence of histopathological variants of oral squamous cell carcinoma: An institutional study
Authors: Mehrotra Saket 
Published: January 2022

Squamous cell carcinoma is the most important and the most common malignant mucosal neoplasm of the head and neck accounting for over 90% of all malignancies. Conventional oral Squamous cell carcinoma is frequently present in general cancerous conditions. It is bundled up with six different variants. Histomorphologically every variant shows a unique appearance. This raises an opportunity for the different diagnostic consideration with the precise management decision.All cases of OSCC reported at our institution Dentopath Pathologies Amravati in past two months were scrutinized. Representative sections containing the full thickness of the tumor were used for histopathological grading. The structure and identification of carcinomas were done microscopically by two expert dentopathologist.In the present study, we screened 100 slides of a conventional epithelial cell carcinoma. Amonst which 30 Slides showed the verrucous carcinoma. On 5 slides adenoid squamous cell carcinoma were observed. Incidence of Papillary squamous cell carcinoma and basaloid squamous cell carcinoma was only 1 out of 100 slides each. Whereas, the spindle cell/sarcomatoid carcinoma was observed on 2 slides. Adenosquamous carcinoma is the rarest variant and hence no incidence of this carcinoma were observed in our study. The behavior of the OSCC varies amongst due to the presence of different morphological type of tumor. A few studies on OSCC malignancy grading with different clinical parameters were made. In the present study different types of variants are seen according to their histopathological appearances.Histopathological knowledge is very important for the precise diagnosis. Squamous cell carcinoma is the most common neoplasm of oral cavity. However, variants of the same show very less frequency. Hence, it became challenge for the appropriate diagnosis as many times a misdiagnosis affects the course of treatment of the patient
Non-extraction orthodontic treatment in a patient with severe anterior crowding
Authors: Jain Abhishek , Jain Garima , Bhide Madhuli , Sharma Pratibha , Sapre Janhavi , Ringane Ankita 
Published: January 2022

A 12 years 6 months old Indian male presented with a chief complaint of irregular upper and lower front teeth. Patient exhibited a mild convex profile on Class l skeletal base with slightly decreased vertical proportions. This was complicated by severe upper and lower labial segment crowding. Also the molar relationship was half unit class ll bilaterally. Since the patient did not want to go for extraction of premolars, treatment involved use of Pendulum appliance along with upper and lower pre-adjusted edgewise appliance (0.022x0.028” slot) with MBT prescription. Various elastics and overlay wires were used along with proximal stripping for the correction of severe crowding in upper and lower anterior teeth.: Clinically Angle’s Class I occlusion was achieved bilaterally with good intercuspal relationship. Vertical growth continued throughout the treatment.
Analyzing the organizational questions of the elite youth academies by the case study of football academy of Debrecen
Authors: Szalánczi Zoltán 
Published: January 2022

Thanks to the effect of the resources flown in to the youth football, the previous, and more simpler structural scheme of the clubs went under a transformation. I will analyse the operation of the youth sport enterprises as economic companies, and the organizational scheme with the most important managerial questions faced in the firm. This will be based on the case study of the Football Academy of Debrecen. In the first part of my publication, I will investigate the evolution and the importance of the sport enterprises, with the relevant scientific literature. In the second part I will discuss the structural scheme of the Football Academy of Debrecen with the analysis of the separate departments. I will search for the differences between the youth sport enterprises and the organisations who are operating as a professional football club.
JEL code: Z2
Investment analysis of a piglet producer farm – a Hungarian case study
Authors: Szűcs István , Szántó László , Szőllősi László 
Published: January 2022

The pig population in Hungary was about 8 million in 1990, while this number dropped to only 2.8 million by 2018. The previously so successful integrated domestic pig farming has almost completely disappeared and most of the smaller farms still operating in the 1990s are no longer functioning. At present, a process of concentration can be observed, which was accompanied by the further specialization of pig farming. The main profile of most pig farms is fattening, but there is a smaller number of farms in Hungary today specialized for piglet production, the successful operation of which requires significantly more expertise and more complex technology.
The main aim of this study is to present the production and economic indicators of a pig farm specialized in piglet production in Hungary as a result of a greenfield investment in the current economic environment, on a case study basis. For this purpose, an economic simulation was prepared based on primary data collection, operating on a deterministic basis, modelling the production and economic processes of the farm. The performed calculation does not derive the economic indicators of the activity from accounting records, but assigns the prices of natural inputs used on the basis of technological data. Primary data and information collection (e.g. technological data, input and output prices, unit cost items, etc.) took place between 2018-2019.
At the purchase prices of pigs in the last two years, which have increased significantly due to the African Swine Fever (ASF), the majority of pig farms in Hungary have an outstanding profit-making capacity. The physical efficiency indicators of the analysed pig farm are almost identical to the average data of such farms in the Netherlands, which has one of the most developed pig industry. The income of the examined pig farm at farm level is about 734 thousand EUR, i.e. 232 EUR per sow. Moreover, this activity is profitable even without subsidies. As a result, the greenfield investment pays off in the 8th year by default (average scenario). The investment has a Net Present Value (NPVr=3%) of EUR 2,609 thousand for 10 years, an Internal Rate of Return of 8.5%, and a Profitability Index (PIr=3%) of 1.3. At the same time, risk factors such as sales prices, output and capacity utilization, and feed costs should be taken into consideration as in extreme cases the return on investment may be unfavourable (pessimistic scenario).
JEL code: D24, M11, Q12
IMPLEMENTATION OF PROFESSIONAL ZAKAT BASED ON THE REGIONAL REGULATION OF PALEMBANG CITY NUMBER 4 OF 2017 AT THE PALEMBANG CITY GOVERNMENT OFFICE
Authors: Tamudin M. , Fitriyati Yusida 
Published: January 2022

This paper examines the implementation of professional zakat based on the regional regulation of the city of Palembang Number 4 of 2017 concerning zakat management at the Palembang city government office.This research is a field research by conducting a study of the laws that apply in society. This study looks at the application of professional zakat based on the Regional Regulation of Palembang City Number 4 of 2017 at the Palembang City Government Office. There are 3 problem formulations in this study, including "1. How is the implementation of professional zakat based on the Regional Regulation of Palembang City Number 4 of 2017 at the Palembang City Government Office? 2. What are the factors that influence the implementation of professional zakat based on the Regional Regulation of Palembang City Number 4 of 2017 at the Palembang City Government Office? 3. What are the efforts made by the Palembang City Government in overcoming the problem of implementing professional zakat based on the Palembang City Regional Regulation Number 4 of 2017? From the results of the study it can be concluded that the implementation of professional zakat based on the regional city regulation of Palembang number 4 of 2017 in the Palembang city government office has been carried out but has not been maximized. There are still many ASNs (civilApparatus) who have not deposited professional zakat to the Palembang City BAZNAS. His awareness of paying professional zakat has only reached 13% of the existing muzakki. The enforcement of administrative sanctions or fines has also not been implemented due to political reasons. The factors that influence the implementation of professional zakat in the Palembang city government office are: the rule of law factor, the Palembang City BAZNAS factor,
Keywords :Implementation, regional regulations, professional zakat.
INTERDISCIPLINARY APPROACH IN THE STUDY OF MARITAL LAW (STUDY OF THE DETERMINATION OF CHILD COSTODY)
Authors: Afriyani Silfa 
Published: January 2022

An interdisciplinary approach is an approach that uses various scientific fields in solving a problem. The determination of child custody is usually decided by considering the age of the child. Children who are not yet mumayiz are taken care of by the mother, but when the child is an adult, they are given the choice to live with the mother or father. Through this study, the author examines the determination of child custody according to Islamic law and the Marriage Law and by using psychology and economics. That the custody of children in care must be assigned to the right person. From this paper, the author concludes that according to Islamic law, the determination of child custody takes into account the age of the child. According to Law no. 1 of 1974 concerning Marriage, the determination of child custody before adulthood is decided by a local court judge. In psychology, the determination of child custody takes into account the mental or psychological aspects of the child. Especially in terms of the child's emotional closeness, closer to the mother or father. So that way, the child's condition will be better in living their daily lives and not getting pressure. Meanwhile, by using economics, the determination of child custody is seen from the financial stability of both parents, both from the mother and from the father. Because in carrying out child care requires financially established, so that the needs of children can be met properly. So, in determining child custody, it can not only be seen from the age of the child but can use other considerations.
Keywords: Child custody, Mother, Father