bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development Testing of High-Pressure Confinement Vessel for Proton Radiography of Explosively Driven Shock Physics Experiments
Authors: Cardon Devin , Spernjak Dusan , Fehlmann Kevin , Fister Matthew , Scarafiotti Jesse , Lakey Matthew , Biel Morgan , Marr-Lyon Mark , Mashburn Keith , Webber Kirk 
Published: November 2022

Abstract
The results of development testing of the Inner Pressure Confinement Vessel (IPCV) are presented here. The IPCV is part of a two-vessel confinement and containment system designed to support proton radiography of shock physics experiments at Los Alamos National Laboratory (LANL). The IPCV is explosively loaded and designed to confine the high-pressure detonation products, material fragments and any other hazardous materials created by explosively driving materials to extreme loading conditions. The IPCV is designed to meet the requirements of ASME Boiler and Pressure Vessel Code Section VIII, Division 3, Code case 2564. The unique and challenging design consideration for the IPCV is the proximity of the High Explosive (HE) charge to the radiographic imaging windows. The radiographic windows are fabricated from low-attenuating Beryllium which aids in obtaining high resolution radiographic images but is also brittle and susceptible to damage. Several rounds of developmental tests were conducted over the course of a few years.
The IPCV is designed to withstand a maximum HE charge size of 30g TNT equivalent. The main components of the IPCV are the Experimental Physics Package (EPP), fragment mitigation assembly, radiographic windows, and gas handling equipment. The radiographic windows are located only a few cm away from the EPP (which houses the HE) and are protected by the fragment mitigation assembly. The gas handling equipment allows for post-shot pressure monitoring and eventual venting of the vessel. The development tests were used to advise the design of the fragment mitigation strategy, develop testing processes and procedures, and collect data for comparison with the engineering models.
Technical Basis of the Code Case Providing Design Rules for the Use of Polyethylene Pipe for Class 3 ASME BPVC Section III, Division 1 Above Ground Piping Systems
Authors: Hebeisen Jason R. , Adams Timothy M. 
Published: November 2022

Abstract
ASME Boiler and Pressure Vessel Code, Section III, Mandatory Appendix XXVI provides rules for buried High Density Polyethylene (HDPE) Pipe for service water or cooling water piping systems. Section III has recently developed rules for above ground High Density Polyethylene (HDPE) piping systems in a Code Case (Code Case N886) that was published with the 2019 edition of the ASME Boiler and Pressure Vessel Code. This paper presents the technical basis of this above ground High Density Polyethylene (HDPE) piping Code Case. It provides the background on the development of the rules for above ground High Density Polyethylene (HDPE) piping systems. The authors completed extensive material testing over last 10 years to build the foundation of the Code Case rules. In addition, the historical background of the testing is given to provide the basis for the stress limits in the above ground case and the stress intensification factors. This paper will also explain the considerations for the selection of a dynamic load factor, the capacity of bolted flanged connections, and the considerations of buckling, which unlike buried pipe apply to above ground piping systems. A complete history and technical background for the basis of the above ground High Density Polyethylene (HDPE) code case rules will be presented in this paper.
Application of Leak-Before-Break to Small Diameter Piping Nozzles With Dissimilar Metal Butt Welds Susceptible to PWSCC Using xLPR
Authors: Cofie Nat , Dedhia Dilip , Dominguez Gary , Uddin Mo , Harrington Craig , Glunt Nate , Shim Do Jun 
Published: November 2022

Abstract
To address the dynamic effects of pipe break required by the General Design Criteria 4 (GDC-4), Appendix A of 10CFR50, deterministic leak-before-break (LBB) analysis (based on margins on leak rate and critical flaw size) as described in Standard Review Plan (SRP) 3.6.3 has been utilized by the nuclear industry. The LBB deterministic margins are generally met for large diameter piping (NPS 10 and greater) using a traditional LRD of 1.0 gpm. For smaller diameter piping, it is typically difficult to meet the required margins using LRD of 1.0 gpm necessitating a lower LRD. An alternate approach is to employ a probabilistic method to determine the probability of rupture and compare it to an appropriate probabilistic acceptance criterion. Recent release of the Extremely Low Probability of Rupture (xLPR) software has made the use of such a probabilistic approach possible.
In this paper, a feasibility study was performed using xLPR to investigate if low probability of rupture can be demonstrated for a typical small diameter piping nozzle with a dissimilar metal (DM) butt weld that is susceptible to primary water stress corrosion cracking (PWSCC). This study assumes a small surface crack and grows this crack to determine if rupture occurs by a through-wall crack or a surface crack. Several sensitivity studies were performed to investigate the effects of key input variables on the rupture probabilities.
The study has shown that it is feasible to justify low probability of rupture for small diameter DM welds susceptible to PWSCC. However, the WRS profile used in the evaluation has strong influence on the probability of rupture. The study has also shown the limitations in applying the deterministic LBB approach on a broader basis to small diameter DM welds in the presence of PWSCC, since rupture by surface cracks instead of through-wall cacks cannot be summarily dismissed and is a fundamental assumption in deterministic LBB with SRP 3.6.3.
Legal epidemiology of paediatric dog bite injuries
Authors: Patterson Kelli N , Beckmeyer Annamarie , Bourgeois Tran , Horvath Kyle Z , Pratt Amy L , Armour Lisa , Wang Ling , Minneci Peter C , Deans Katherine J , Thakkar Rajan K , Parasidis Efthimios 
Published: November 2022

BackgroundDog bite injuries cause over 100 000 paediatric emergency department visits annually. Our objective was to analyse associations between regional dog ownership laws and incidence of paediatric dog bites.MethodsThis observational study used an online search to locate local dog-related policies within Ohio cities. Data collected by Ohio Partners For Kids from 2011 through 2020 regarding claims for paediatric dog bite injuries were used to compare areas with and without located policies and the incidence of injury.ResultsOur cohort consisted of 6175 paediatric patients with dog bite injury encounters. A majority were white (79.1%), male (55.0%), 0–5 years old (39.2%) and did not require hospital admission (98.1%). Seventy-nine of 303 cities (26.1%) had city-specific policies related to dogs. Overall, the presence of dog-related policies was associated with lower incidence of dog bite injury claims (p=0.01). Specifically, metropolitan areas and the Central Ohio region had a significantly lower incidence when dog-related policies were present (324.85 per 100 000 children per year when present vs 398.56 when absent; p<0.05; 304.87 per 100 000 children per year when present vs 411.43 when absent; p<0.05).ConclusionsThe presence of city-specific dog-related policies is associated with lower incidence of paediatric dog bite injury claims, suggesting that local policy impacts this important public health issue. There are limited dog-related policies addressing dog bite prevention, with inconsistencies in breadth and depth. Creating consistent, practical requirements among policies with vigorous enforcement could ameliorate public health concerns from paediatric dog bite injuries.
Characterization and whole-genome sequencing of an extreme arsenic-tolerant Citrobacter freundii SRS1 strain isolated from Savar area in Bangladesh
Authors: Uddin Mohammed Jafar , Haque Farhana , Jabeen Ishrat , Shuvo Sabbir R. 
Published: November 2022

Citrobacter freundii SRS1, gram-negative bacteria, were isolated from Savar, Bangladesh. The strain could tolerate up to 80 mmol L−1 sodium arsenite, 400 mmol L−1 sodium arsenate, 5 mmol L−1 manganese sulfate, 3 mmol L−1 lead nitrate, 2.5 mmol L−1 cobalt chloride, 2.5  mmol L−1 cadmium acetate, and 2.5 mmol L−1 chromium chloride. The whole-genome sequencing revealed that the genome size of C. freundii SRS1 is estimated to be 5.4 Mb long, and the G + C content is 51.7%. The genome of C. freundii SRS1 contains arsA, arsB, arsC, arsD, arsH, arsR, and acr3 genes for arsenic resistance; czcA, czcD, cbiN, and cbiM genes for cobalt resistance; chrA and chrB genes for chromium resistance; mntH, sitA, sitB, sitC, and sitD genes for manganese resistance; and zntA gene for lead and cadmium resistance. This novel acr3 gene has never previously been reported in any C. freundii strain except SRS1. A set of 130 completely sequenced strains of C. freundii was selected for phylogenomic analysis. The phylogenetic tree showed that the SRS1 strain is closely related to the C. freundii 62 strain. Further analyses of the genes involved in metal and metalloid resistance might facilitate identifying the mechanisms and pathways involved in high metal resistance in the C. freundii SRS1 strain.
O espaço lisboeta em "Memorial do convento": entre o sagrado e o profano
Authors: Mello Marco Aurélio 
Published: November 2022

Utilizando-se de uma perspectiva geralmente marginalizada pela historiografia oficial, o narrador de "Memorial do convento", romance de José Saramago (1922-2010) publicado em 1982, elege como protagonistas personagens até então anônimos, como é o caso de Baltasar Sete-Sóis, metonímia dos homens esquecidos pela história oficial, o qual, regressando de guerra com a Espanha, chega à Lisboa do início do século XVIII. O presente artigo objetiva identificar como o narrador de Memorial do convento reconstrói essa Lisboa, especialmente no que concerne aos espaços da cidade portuguesa. Este estudo revela que tais espaços são marcados por forte influência da Igreja Católica e da arte barroca, estética caracterizada pela intensidade, pela pujança e pela conciliação de polos opostos, como é o caso do sagrado e do profano.
Upper limb manual training for children with cerebral palsy: A systematic review and network meta-analysis of randomized controlled trials
Authors: Yang Fu-An , Lee Ting-Hsuan , Huang Shih-Wei , Liou Tsan-Hon , Escorpizo Reuben , Chen Hung-Chou 
Published: November 2022

Objective There are different upper limb manual training protocols, namely constraint-induced movement therapy, modified constraint-induced movement therapy, hand–arm bimanual intensive training, hand–arm bimanual intensive training including lower extremity, action observation training, and mirror therapy, available for improving functional outcomes in children with cerebral palsy. However, the effect and priority of these strategies remain unclear. Data sources We searched the PubMed, Cochrane Library, and Embase databases for relevant articles from inception to October 12, 2022. Review methods To assess the effect and priority of different strategies of upper limb manual training protocols through a systematic review and network meta-analysis of randomized controlled trials. Results We included 22 randomized controlled trials in this network meta-analysis. The ranking probability and standard mean differences with 95% credible intervals of the comparison between placebo and other forms of upper limb manual training were as follows: mirror therapy = 2.83 (1.78, 3.88), hand–arm bimanual intensive training including the lower extremity = 0.53 (0.09, 0.96), constraint-induced movement therapy = 0.44 (0.18, 0.71), hand–arm bimanual intensive training = 0.41 (0.15, 0.67), modified constraint-induced movement therapy = 0.39 (0.03, 0.74), and action observation training = 0.18 ( − 0.29, 0.65). No significant inconsistency was noted between the results of direct and indirect comparisons. Conclusion We suggest that mirror therapy could be the upper limb manual training protocol of choice for improving functional outcomes in patients with cerebral palsy.
The impact of COVID-19 on labour markets and living standards in Mauritius
Authors: Ranzani Marco , Kern Andreas 
Published: November 2022

AbstractUnderstanding the distributional impact of the COVID-19 crisis on the labour market and ultimately on the living standards of the population is key to designing adequate policy responses to shield individuals’ and families’ livelihoods. This article illustrates the impact of COVID-19 on the labour market as well as on living standards in the case of a small open economy: Mauritius. We present descriptive evidence based on a unique set of telephone household surveys, representative of the Mauritian population, conducted between May 2020 and March 2021. We find that women had a higher risk of losing their job and leaving the labour force, reversing a decade-long trend of increasing labour force participation. Low-skill workers in sectors that depend on global demand – and even more so if employed informally – together with women were more likely to be affected by the crisis. One in three households reported a loss in income since the start of the pandemic, and the probability of experiencing this shock increases with the number of household members who lost their job and who were employed informally. From a policy perspective, our findings underscore the negative distributional consequences of the pandemic and provide substantive evidence for the viability of a further proactive policy stance to shield the livelihoods of vulnerable households during the economic recovery phase.
Assessment of Internal Nasal Dimensions of Individuals With Cleft Lip and Palate and Obstructive Sleep Apnea Syndrome by Computed Tomography
Authors: Loureiro Natalia Bortotti , Marzano-Rodrigues Maria Noel , Trindade-Suedam Ivy Kiemle , D Aquino Alessandro , Trindade Sergio Henrique Kiemle 
Published: November 2022

To evaluate nasal cavity (NC) dimensions of individuals with cleft lip and/or palate (CL/P), obstructive sleep apnea (OSA), and primary snoring, by tomographic image analysis, compared to individuals with OSA without CL/P (N-CL/P). Cross-sectional and retrospective. Tertiary referral center. Patients were divided into 2 groups: (G1) CL/P + OSA or primary snoring, n = 11; (G2) N-CL/P + OSA, n = 13. NC tomographic images were reconstructed using ITK-SNAP software, and measurements were obtained from these three-dimensional models using SpaceClaim software. Total NC volumes, right and left NC volumes, and volumes of the nostril to the nasal valve (V1) and from the nasal valve to the superior limit of the nasopharynx (V2), cross-sectional areas, and perimeters. NC volumes (total, right, and left sides), V1, and V2, though smaller in the CL/P + OSA, did not differ significantly from the N-CL/P + OSA. Cross-sectional areas and perimeters of the superior limit of the nasopharynx, in the CL/P + OSA, presented significantly higher values compared to the N-CL/P + OSA ( P ≤ .05). The internal nasal dimensions of patients with CL/P do not seem to be part of the etiopathogenesis, nor constitute a risk factor for OSA with greater severity, in this special group of patients.
Autism voices: Perspectives of the needs, challenges, and hopes for the future of autistic youth
Authors: Tesfaye Rackeb , Courchesne Valerie , Mirenda Pat , Mitchell Wendy , Nicholas David , Singh Ilina , Zwaigenbaum Lonnie , Elsabbagh Mayada 
Published: November 2022

The Autism Voices study draws on novel inclusive methods to obtain the first-person experiences of autistic youth with a range of cognitive and verbal abilities. Thirty-one autistic youth were interviewed with a strength-based protocol, enabling them to provide responses in the modality of their choice. Dynamics between youth and their environments such as home, school, and community were explored. Youth were questioned about their interests, plans for the future, experiences with various emotions, and experience of autism. Based on a thematic analysis, six themes emerged: (1) autistic identities, (2) thinking about the future, (3) seeking social connection on their own terms, (4) seeking autonomy, (5) school as both a stressor and social facilitator, and (6) experiences of stress and anxiety. The experiences described by autistic youth parallel many of the aspirations and challenges of typically developing adolescents, while being uniquely shaped by their autism. We discuss how these insights shared by autistic youth can facilitate active involvement in their communities, promote well-being, and promote optimal transition into adulthood. Autism Voices demonstrates that partnering with multiple stakeholders and the use of inclusive methodologies are pivotal steps toward capturing the voices of all autistic youth. Lay abstract Currently, our understanding of the adolescent period for autistic youth has relied on the expertise of researchers, clinicians, parents, and teachers, yet rarely involves their unique first-person experiences. Our study attempted to understand the experiences and perspectives of autistic adolescents in their home, school, and community environments using the Autism Voices protocol, a semi-structured interview specifically designed and tailored to engage with autistic youth with various language and intellectual levels. The analysis of the 31 interviews conducted with autistic adolescents aged 11–18 years highlighted six themes: (1) autistic identities, (2) thinking about the future, (3) seeking social connection on their own terms, (4) seeking autonomy, (5) school as both a stressor and social facilitator, and (6) experiences of stress and anxiety. These results highlight similarities and differences in the adolescent experiences of autistic youth compared to their typically developing peers. Our findings suggest that by removing assumptions about the experiences of autistic individuals and investing in inclusive interview methods, we can faithfully capture the experiences of autistic youth regardless of their communication and cognitive abilities. Being able to capture and amplify these diverse voices will facilitate the active involvement of autistic communities in research and clinical and policy decisions that impact them.
The potential activity of biosynthesized silver nanoparticles of Pseudomonas aeruginosa as an antibacterial agent against multidrug-resistant isolates from intensive care unit and anticancer agent
Authors: Abeer Mohammed A. B. , Abd Elhamid Mona Mohamed , Khalil Magdy Kamal Mohammed , Ali Abdallah Soubhy , Abbas Rateb Nabil 
Published: November 2022

Abstract
Background
Antibiotic resistance is a global problem; especially the multidrug-resistant bacteria are a serious and fatal problem in the intensive care unit. Interestingly, biosynthesized silver nanoparticles are the promising key to eliminate these microbes. Using Pseudomonas aeruginosa supernatant is an easy and cheap method in silver nanoparticle biosynthesis. The biosynthesis conditions were adjusted, and the profiling of the biosynthesized silver nanoparticles was confirmed.

Results
The UV spectroscopy at a wavelength at 400 nm was 0.539 A.U., transmission electron microscope showed nanoparticles were homogeneous with a square and spherical shape, its average size 20 nm, The capping material and the existence of silver nanoparticles were confirmed using Fourier transform infrared spectroscopy, and energy dispersive X-ray spectroscopy. The minimum inhibitory concentration was 1 mg/ml against multidrug-resistant bacteria, and LC50 was 62.307 μg/ml on the hepatocellular carcinoma cell line.

Conclusions
Microbial-synthesized silver nanoparticles have a potential application to combat multidrug-resistant bacteria, especially in the intensive care unit.
Collateral status, hyperglycemia, and functional outcome after acute ischemic stroke
Authors: Arteaga Daniel F. , Ulep Robin , Kumar Kevin K. , Southerland Andrew M. , Conaway Mark R. , Faber James , Wintermark Max , Joyner David , Sharashidze Vera , Hirsch Karen , Giurgiutiu Dan-Victor , Hannawi Yousef , Aziz Yasmin , Shutter Lori , Visweswaran Anita , Williams Alana , Williams Kori , Gunter Sonya , Haughey Heather M. , Bruno Askiel , Johnston Karen C. , Patel Vishal N. ,   SHINE Trial Investigators
Published: November 2022

Abstract
Background
Mixed data exist regarding the association between hyperglycemia and functional outcome after acute ischemic stroke when accounting for the impact of leptomeningeal collateral flow. We sought to determine whether collateral status modifies the association between treatment group and functional outcome in a subset of patients with large vessel occlusion enrolled in the Stroke Hyperglycemia Insulin Network Effort (SHINE) trial.

Methods
In this post-hoc analysis, we analyzed patients enrolled into the SHINE trial with anterior circulation large vessel occlusion who underwent imaging with CT angiography prior to glucose control treatment group assignment. The primary analysis assessed the degree to which collateral status modified the effect between treatment group and functional outcome as defined by the 90-day modified Rankin Scale score. Logistic regression was used to model the data, with adjustments made for thrombectomy status, age, post-perfusion thrombolysis in cerebral infarction (TICI) score, tissue plasminogen activator (tPA) use, and baseline National Institutes of Health Stroke Scale (NIHSS) score. Five SHINE trial centers contributed data for this analysis. Statistical significance was defined as a p-value < 0.05.

Results
Among the 1151 patients in the SHINE trial, 57 with angiographic data were included in this sub-analysis, of whom 19 had poor collaterals and 38 had good collaterals. While collateral status had no effect (p = 0.855) on the association between glucose control treatment group and functional outcome, patients with good collaterals were more likely to have a favorable functional outcome (p = 0.001, OR 5.02; 95% CI 1.37–16.0).

Conclusions
In a post-hoc analysis using a subset of patients with angiographic data enrolled in the SHINE trial, collateral status did not modify the association between glucose control treatment group and functional outcome. However, consistent with prior studies, there was a significant association between good collateral status and favorable outcome in patients with large vessel occlusion stroke.

Trial registration
ClinicalTrials.gov Identifier is NCT01369069. Registration date is June 8, 2011.