bluuebunny/crossref_metadata_2025_split huggingface dataset:
BASS. XXIV. The BASS DR2 Spectroscopic Line Measurements and AGN Demographics
Authors: Oh Kyuseok , Koss Michael J. , Ueda Yoshihiro , Stern Daniel , Ricci Claudio , Trakhtenbrot Benny , Powell Meredith C. , den Brok Jakob S. , Lamperti Isabella , Mushotzky Richard , Ricci Federica , Bär Rudolf E. , Rojas Alejandra F. , Ichikawa Kohei , Riffel Rogério , Treister Ezequiel , Harrison Fiona , Urry C. Megan , Bauer Franz E. , Schawinski Kevin 
Published: July 2022

Abstract
We present the second catalog and data release of optical spectral line measurements and active galactic nucleus (AGN) demographics of the BAT AGN Spectroscopic Survey, which focuses on the Swift-BAT hard X-ray detected AGNs. We use spectra from dedicated campaigns and publicly available archives to investigate spectral properties of most of the AGNs listed in the 70 month Swift-BAT all-sky catalog; specifically, 743 of the 746 unbeamed and unlensed AGNs (99.6%). We find a good correspondence between the optical emission line widths and the hydrogen column density distributions using the X-ray spectra, with a clear dichotomy of AGN types for N
H = 1022 cm−2. Based on optical emission-line diagnostics, we show that 48%–75% of BAT AGNs are classified as Seyfert, depending on the choice of emission lines used in the diagnostics. The fraction of objects with upper limits on line emission varies from 6% to 20%. Roughly 4% of the BAT AGNs have lines too weak to be placed on the most commonly used diagnostic diagram, [O iii]λ5007/Hβ versus [N ii]λ6584/Hα, despite the high signal-to-noise ratio of their spectra. This value increases to 35% in the [O iii]λ5007/[O ii]λ3727 diagram, owing to difficulties in line detection. Compared to optically selected narrow-line AGNs in the Sloan Digital Sky Survey, the BAT narrow-line AGNs have a higher rate of reddening/extinction, with Hα/Hβ > 5 (∼36%), indicating that hard X-ray selection more effectively detects obscured AGNs from the underlying AGN population. Finally, we present a subpopulation of AGNs that feature complex broad lines (34%, 250/743) or double-peaked narrow emission lines (2%, 17/743).
BASS. XXVI. DR2 Host Galaxy Stellar Velocity Dispersions
Authors: Koss Michael J. , Trakhtenbrot Benny , Ricci Claudio , Oh Kyuseok , Bauer Franz E. , Stern Daniel , Caglar Turgay , den Brok Jakob S. , Mushotzky Richard , Ricci Federica , Mejía-Restrepo Julian E. , Lamperti Isabella , Treister Ezequiel , Bär Rudolf E. , Harrison Fiona , Powell Meredith C. , Privon George C. , Riffel Rogério , Rojas Alejandra F. , Schawinski Kevin , Urry C. Megan 
Published: July 2022

Abstract
We present new central stellar velocity dispersions for 484 Sy 1.9 and Sy 2 from the second data release of the Swift/BAT AGN Spectroscopic Survey (BASS DR2). This constitutes the largest study of velocity dispersion measurements in X-ray-selected obscured active galactic nuclei (AGN) with 956 independent measurements of the Ca ii H and K λ3969, 3934 and Mg I λ5175 region (3880–5550 Å) and the calcium triplet region (8350–8730 Å) from 642 spectra mainly from VLT/X-Shooter or Palomar/DoubleSpec. Our sample spans velocity dispersions of 40–360 km s1, corresponding to 4–5 orders of magnitude in black hole mass (M
BH = 105.5−9.6
M
⊙), bolometric luminosity (L
bol ∼ 1042–46 erg s−1), and Eddington ratio (L/L
Edd ∼ 10−5 to 2). For 281 AGN, our data and analysis provide the first published central velocity dispersions, including six AGN with low-mass black holes (M
BH = 105.5−6.5
M
⊙), discovered thanks to high spectral resolution observations (σ
inst ∼ 25 km s−1). The survey represents a significant advance with a nearly complete census of velocity dispersions of hard X-ray–selected obscured AGN with measurements for 99% of nearby AGN (z < 0.1) outside the Galactic plane (∣b∣ > 10°). The BASS AGN have much higher velocity dispersions than the more numerous optically selected narrow-line AGN (i.e., ∼150 versus ∼100 km s−1) but are not biased toward the highest velocity dispersions of massive ellipticals (i.e., >250 km s−1). Despite sufficient spectral resolution to resolve the velocity dispersions associated with the bulges of small black holes (∼104–5
M
⊙), we do not find a significant population of super-Eddington AGN. Using estimates of the black hole sphere of influence from velocity dispersion, direct stellar and gas black hole mass measurements could be obtained with existing facilities for more than ∼100 BASS AGN.
The ESA Hera Mission: Detailed Characterization of the DART Impact Outcome and of the Binary Asteroid (65803) Didymos
Authors: Michel Patrick , Küppers Michael , Bagatin Adriano Campo , Carry Benoit , Charnoz Sébastien , Leon Julia de , Fitzsimmons Alan , Gordo Paulo , Green Simon F. , Hérique Alain , Juzi Martin , Karatekin Özgür , Kohout Tomas , Lazzarin Monica , Murdoch Naomi , Okada Tatsuaki , Palomba Ernesto , Pravec Petr , Snodgrass Colin , Tortora Paolo , Tsiganis Kleomenis , Ulamec Stephan , Vincent Jean-Baptiste , Wünnemann Kai , Zhang Yun , Raducan Sabina D. , Dotto Elisabetta , Chabot Nancy , Cheng Andy F. , Rivkin Andy , Barnouin Olivier , Ernst Carolyn , Stickle Angela , Richardson Derek C. , Thomas Cristina , Arakawa Masahiko , Miyamoto Hirdy , Nakamura Akiko , Sugita Seiji , Yoshikawa Makoto , Abell Paul , Asphaug Erik , Ballouz Ronald-Louis , Bottke William F. , Lauretta Dante S. , Walsh Kevin J. , Martino Paolo , Carnelli Ian 
Published: July 2022

Abstract
Hera is a planetary defense mission under development in the Space Safety and Security Program of the European Space Agency for launch in 2024 October. It will rendezvous in late 2026 December with the binary asteroid (65803) Didymos and in particular its moon, Dimorphos, which will be impacted by NASA’s DART spacecraft on 2022 September 26 as the first asteroid deflection test. The main goals of Hera are the detailed characterization of the physical properties of Didymos and Dimorphos and of the crater made by the DART mission, as well as measurement of the momentum transfer efficiency resulting from DART’s impact. The data from the Hera spacecraft and its two CubeSats will also provide significant insights into asteroid science and the evolutionary history of our solar system. Hera will perform the first rendezvous with a binary asteroid and provide new measurements, such as radar sounding of an asteroid interior, which will allow models in planetary science to be tested. Hera will thus provide a crucial element in the global effort to avert future asteroid impacts at the same time as providing world-leading science.
Expected Investigation of the (65803) Didymos–Dimorphos System Using the RGB Spectrophotometry Data Set from the LICIACube Unit Key Explorer (LUKE) Wide-angle Camera
Authors: Poggiali Giovanni , Brucato John R. , Hasselmann Pedro H. , Ieva Simone , Perna Davide , Pajola Maurizio , Lucchetti Alice , Deshapriya Jasinghege D. P. , Della Corte Vincenzo , Mazzotta Epifani Elena , Rossi Alessandro , Ivanovski Stavro L. , Zinzi Angelo , Meneghin Andrea , Amoroso Marilena , Pirrotta Simone , Impresario Gabriele , Dotto Elisabetta , Bertini Ivano , Capannolo Andrea , Cremonese Gabriele , Cotugno Biagio , Dall’Ora Massimo , Di Tana Valerio , Gai Igor , Lavagna Michèle , Miglioretti Federico , Modenini Dario , Palumbo Pasquale , Simioni Emanuele , Simonetti Simone , Tortora Paolo , Zannoni Marco , Zanotti Giovanni 
Published: July 2022

Abstract
The Light Italian Cubesat for Imaging of Asteroids (LICIACube) is part of the NASA Double Asteroid Redirection Test (DART), the first mission aiming to demonstrate the applicability of the kinetic impactor method for planetary defense. The mission was launched on 2021 November 24 to perform the impact experiment on Dimorphos, the small secondary of the binary asteroid (65803) Didymos. The 6U LICIACube, stored as a piggyback of the DART spacecraft, is the first Italian mission operating in deep space managed by the Italian Space Agency that will witness the effects of the DART impact on Dimorphos. On board LICIACube, there is a suite of cameras that will perform imaging of Didymos and Dimorphos to investigate the DART impact effects and study the binary system. Among them, the LICIACube Unit Key Explorer (LUKE), a wide-angle camera coupled to an RGB Bayer pattern filter, will be pivotal to constrain the surface composition and heterogeneity of the binary system due to differences in surface properties linked with possible space weathering effects and/or the presence of exogenous material. Multiband photometric analysis of LUKE data and laboratory experiments in support of data interpretation will provide new insights on the binary asteroid nature and evolution. Moreover, photometric phase curve analysis will reveal the scattering properties of the granular surface medium providing important constraints for the microphysical properties of the Didymos–Dimorphos system. In this work, we will present the state of the art of the LUKE scientific activities with an overview of the instrument setup, science operations, and expected results.
Dual-Energy Computed Tomography Has Additional Prognostic Value Over Clinical Measures in Gout Including Tophi: A Systematic Literature Review
Authors: Stauder Sally K. , Peloso Paul M. 
Published: July 2022

Objective This systematic literature review determined whether there is clinical utility for dual-energy computed tomography (DECT) to inform on prognosis for patients with gout. With DECT, individualized treatment plans could be developed based on the patient's unique urate burden, with DECT being used as a clinical outcome measure in gout management. Methods To evaluate DECT as a reliable, valid, and sensitive prognostic instrument, a librarian-assisted search was undertaken in PubMed and Embase for articles on gout and DECT informing on reliability; content, construct, and criterion validity; sensitivity to change; and minimum clinically important changes. Results This systematic literature review showed that DECT has high intra- and interrater reliability. Tophus burden correlates with functional loss to show content validity. DECT volume is positively correlated with death, cardiovascular risk factors, and the risk for future gout flares. DECT has excellent sensitivity to change with effective urate-lowering therapies. Conclusion DECT is a promising prognostic tool based on its high reliability, sensitivity to change, and emerging validity. Additional large, well-designed, prospective cohort studies are needed to fully evaluate its prognostic utility. This systematic review suggests that DECT very likely has additional prognostic information beyond clinical tophi assessment alone.
Effect of Fatigue on Health-Related Quality of Life and Work Productivity in Psoriatic Arthritis: Findings From a Real-World Survey
Authors: Gossec Laure , Walsh Jessica A. , Michaud Kaleb , Holdsworth Elizabeth , Peterson Steve , Meakin Sophie , Yang Feifei , Booth Nicola , Chakravarty Soumya D. , Piercy James , Dennis Natalie , Ogdie Alexis 
Published: July 2022

Objective To evaluate fatigue frequency and severity among patients with psoriatic arthritis (PsA) and assess the effect of fatigue severity on patient-reported outcome measures (PROMs) assessing quality of life, function, and work productivity. Methods Data were derived from the Adelphi Disease Specific Programme, a cross-sectional survey conducted in 2018 in the United States and Europe. Patients had physician-confirmed PsA. Fatigue was collected as a binary variable and through its severity (0-10 scale, using the 12-item Psoriatic Arthritis Impact of Disease fatigue question) from patients; physicians also reported patient fatigue (yes/no). Other PROMs included the 5-level EuroQol 5-dimension questionnaire (EQ-5D-5L) for health-related quality of life (HRQOL), Health Assessment Questionnaire–Disability Index, and Work Productivity and Activity Impairment Questionnaire. Multivariate linear regression was used to evaluate the association between fatigue severity and other PROMs. Results Among the 831 included patients (mean age 47.5 yrs, mean disease duration 5.3 yrs, 46.9% female, 48.1% receiving a biologic), fatigue was reported by 78.3% of patients. Patients with greater fatigue severity had greater disease duration, PsA severity, pain levels, body surface area affected by psoriasis, and swollen and tender joint counts (all P < 0.05). In multivariate analyses, patients with greater fatigue severity experienced worse physical functioning, HRQOL, and work productivity (all P < 0.001). Presence of fatigue was underreported by physicians (reported in only 32% of patients who self-reported fatigue). Conclusion Prevalence of patient-reported fatigue was high among patients with PsA and underrecognized by physicians. Fatigue severity was associated with altered physical functioning, work productivity, and HRQOL.
Development and Validation of a Self-Administered Questionnaire Measuring Essential Knowledge in Patients With Axial Spondyloarthritis
Authors: Beauvais Catherine , Pereira Bruno , Pham Thao , Sordet Christelle , Claudepierre Pascal , Fayet Françoise , Wendling Daniel , Costantino Félicie , Carton Laurence , Grange Laurent , Soubrier Martin , Legoupil Nathalie , Perdriger Aleth , Tavares Isabel , Dernis Emmanuelle , Gossec Laure , Rodère Malory 
Published: July 2022

ObjectiveTo develop and validate a patient knowledge questionnaire regarding axial spondyloarthritis (axSpA).MethodsKnowledge considered essential for patients with axSpA was identified through Delphi rounds among rheumatologists, healthcare professionals (HCPs), and patients, then reformulated to develop the knowledge questionnaire. Cross-sectional validation was performed in 14 rheumatology departments to assess internal validity (Kuder-Richardson coefficient), external validity, acceptability, reproducibility (Lin concordance correlation coefficient), and sensitivity to change (knowledge score before vs after patient education sessions and effect size).ResultsThe Spondyloarthritis Knowledge Questionnaire (SPAKE) is a self-administered 42-item questionnaire with a 32-item short form, both scored 0 to 100, assessing knowledge of disease, comorbidities, pharmacological treatments, nonpharmacological treatments, self-care, and adaptive skills. In the validation study (130 patients; 67 [51.5%] male, mean age 43.5 [SD 12.9] yrs), the mean (SD) score of the long-form questionnaire was 71.6 (15.4), with higher scores (better knowledge) in nonpharmacological treatments and adaptive skills and lower scores in cardiovascular comorbidity and pharmacological treatments. Acceptability was good, with no missing data; the internal validity coefficient was 0.85. Reproducibility was good (0.81, 95% CI 0.72-0.89). SPAKE showed good sensitivity to change; scores were 69.2 (15.3) then 82.7 (14.0) after patient education sessions (Hedges effect size = 0.92, 95% CI 0.52-1.31).ConclusionSPAKE is a knowledge questionnaire for patients with axSpA, developed with the involvement of HCPs and patients and reflecting current recommendations for the management of axSpA. SPAKE will be useful in assessing knowledge acquisition and self-management strategies in routine care and research.
Systems Immunology Analyses of STAT1 Gain-of-Function Immune Phenotypes Reveal Heterogeneous Response to IL-6 and Broad Immunometabolic Roles for STAT1
Authors: Kaviany Saara , Bartkowiak Todd , Dulek Daniel E , Khan Yasmin W , Hayes Madeline J , Schaefer Samuel G , Ye Xiang , Dahunsi Debolanle O , Connelly James A , Irish Jonathan M , Rathmell Jeffrey C 
Published: July 2022

Abstract
Patients with STAT1 gain-of-function (GOF) pathogenic variants have enhanced or prolonged STAT1 phosphorylation following cytokine stimulation and exhibit increased yet heterogeneous susceptibility to infections, autoimmunity, and cancer. Although disease phenotypes are diverse and other genetic factors contribute, how STAT1 GOF affects cytokine sensitivity and cell biology remains poorly defined. In this study, we analyzed the immune and immunometabolic profiles of two patients with known pathogenic heterozygous STAT1 GOF mutation variants. A systems immunology approach of peripheral blood cells from these patients revealed major changes in multiple immune cell compartments relative to healthy adult and pediatric donors. Although many phenotypes of STAT1 GOF donors were shared, including increased Th1 cells but decreased class-switched B cells and plasmacytoid dendritic cell populations, others were heterogeneous. Mechanistically, hypersensitivity for cytokine-induced STAT1 phosphorylation in memory T cell populations was particularly evident in response to IL-6 in one STAT1 GOF patient. Immune cell metabolism directly influences cell function, and the STAT1 GOF patients shared an immunometabolic phenotype of heightened glucose transporter 1 (GLUT1) and carnitine palmitoyl transferase 1A (CPT1a) expression across multiple immune cell lineages. Interestingly, the metabolic phenotypes of the pediatric STAT1 GOF donors more closely resembled or exceeded those of healthy adult than healthy age-similar pediatric donors, which had low expression of these metabolic markers. These results define new features of STAT1 GOF patients, including a differential hypersensitivity for IL-6 and a shared increase in markers of metabolism in many immune cell types that suggests a role for STAT1 in metabolic regulation of immunity.
An Observational Study on Empathy and Factors Associated with Individual Variations in Empathy Levels Among Youth in Central Kerala
Authors: Sebastian Shaliet Rose , Saji Joyal Alias , Mathew Geethu , Babu Bichu P. 
Published: July 2022

Background:
Empathy is a social skill that exerts influence on the quality of social relationships. The importance of being empathetic is not only limited to the health care field. An empathetic person is able to understand the emotions of others, accurately express their feelings, comprehend others’ situations and act appropriately. According to the census data of 2011, one-fifth of India’s population is made up of the youth. Added to the volatile nature of the age, our youth face challenges from social exclusion, gender-based violence, and the lack of access to rights and opportunities.

Aim:
The aim of the study is to measure empathy levels among young adults aged 19–24 years in Central Kerala and to find out the factors associated with individual variations in empathy levels among them.

Materials and Methods:
A cross-sectional survey was conducted among 610 young adults of both gender in Pathanamthitta, Kottayam, Alappuzha, Kollam, and Trivandrum districts in South-central Kerala.

Results:
Good academic performance among study participants was found to be significantly associated with fantasy scale. The personal distress scale among study participants was found to be significantly associated with burnout, medical stream, and involvement in humanitarian acts. Burnout scores of study participants were found to be inversely correlated with fantasy scale, empathic concern, personal distress, and the combined interpersonal reactivity index.

Conclusion:
The present study sheds light on the prevalence of empathy and humanistic values among the youth in Kerala.
Development and Psychometric Properties of the Mental Health Literacy Questionnaire (MHLQ) Among Young Iranian Soldiers
Authors: Soleimani-Sefat Erfan , Parandeh Akram , Rahmati Fatemeh , Kamalikhah Tahereh 
Published: July 2022

Background:
Prevention of the incidences of mental disorders, psychological problems, or their rapid diagnosis is an important issue that has led to the creation of a mental health literacy concept and the development of standard tools for evaluating them. This study is the first step in the designing and psychometrics of the Mental Health Literacy Questionnaire (MHLQ) in Iran. The purpose of this study was to design the psychometric properties of the MHLQ in soldiers.

Methods:
This study is a methodological study that was designed in three phases: 1) Designing the instrument, 2) Assessing the items, and 3) Psychometric assessment. This study was conducted during 2017-2018, and the soldiers were selected by using a convenience sampling method from different garrisons of Tehran, Iran. To evaluate the content validity of the questionnaire 10 experts, to evaluate the face validity 9 soldiers, and for the pilot study 103 soldiers formed the sample size. Finally, construct validity was assessed among 251 soldiers.

Results:
In the first phase, 78 items were collected and designed. Then, based on the experts’ opinions and preliminary studies, the items were reduced to 52 in the “Assessing the items phase” and then to 42 items in the psychometric phase. In the third phase, 31 items remained in the final version. The CVR and CVI scores of the 52 items were 0.91 and 0.94, respectively. Exploratory factor analysis revealed a 4-factor structure with 31 items of special value that were higher than five that accounted for 55.04 of the total scale variance. The fit indices values indicated that the model is fit for the data. In the total scale, the test–retest reliability and Cronbach's alpha were 0.81 and 0.76, respectively.

Conclusion:
The MHLQ of soldiers has appropriate psychometric properties and can be considered as a suitable tool for evaluation and screening as well as a basis for educational and research interventions.
Prevalence of Tobacco Use in Adults; 2016 Nationally Representative Household Survey in Iran
Authors: Riazi-Isfahani Sahand , Abdi Zhaleh , Sheidaei Ali , Ahmadnezhad Elham 
Published: July 2022

Background:
Tobacco use is an established preventable risk factor for many noncommunicable diseases and is considered as an important indicator for monitoring progress towards Universal Health Coverage (UHC) and Sustainable Development Goals (SDGs). This study aimed to determine the situation of tobacco use among Iranian adults using 2016 household survey.

Methods:
This is a secondary analysis of the data from 2016 nationally representative STEPwise approach to Surveillance (STEPs) survey with a sample size of 31,050. The data on tobacco consumption was gathered using questions incorporated in the survey questionnaire.

Results:
The prevalence of current tobacco use in Iran was 25.2 % (24.4-25.9) in men versus 4% (3.7-4.3) in women. The prevalence was higher in rural areas and among second wealth group. The prevalence of current daily cigarette smoking was 20.1% (19.4-20.7) in men versus 0.9% (0.8-1.1) in women). Average number of cigarettes per day among current cigarette smokers was 14.5% (14.1-14.9), mean age at start smoking among daily cigarette smokers was 21.6% (21.1-22), and 95.2% (94.4-96) of daily current daily cigarette smokers attempted for cessation during past 12 months. Prevalences of exposure to secondhand cigarette smoke among nonsmokers at homes and workplaces were 23.21% (22.65-23.76) and 18.04% (17.2-18.87), respectively.

Conclusions:
There was a large difference between the prevalence of tobacco use between men and women (25.2% vs. 4%). Higher prevalences of tobacco use in rural areas and among lower wealth quintiles require more equity-based approaches in tobacco combatting actions.