bluuebunny/crossref_metadata_2025_split huggingface dataset:
Voice phenomenology as a mirror of the past
Authors: van den Berg David , Tolmeijer Eva , Jongeneel Alyssa , Staring Anton B. P. , Palstra Eline , van der Gaag Mark , Hardy Amy 
Published: January 2022

AbstractBackgroundPost-traumatic mechanisms are theorised to contribute to voice-hearing in people with psychosis and a history of trauma. Phenomenological links between trauma and voices support this hypothesis, as they suggest post-traumatic processes contribute to the content of, and relationships with, voices. However, research has included small samples and lacked theory-based comprehensive assessments.MethodIn people with distressing voices (n = 73) who experienced trauma prior to voice-hearing, trauma–voice links were assessed both independently and dependently (descriptions were presented and rated separately and together, respectively) by both participants and researchers. A structured coding frame assessed four types of independent links (i.e. victimisation type, physiological-behavioural, emotional, and cognitive response themes including negative self-beliefs) and three types of dependent links: relational (similar interaction with/response to, voice and trauma); content (voice and trauma content are exactly the same); and identity (voice identity is the same as perpetrator).ResultsIndependent links were prevalent in participants (51–58%) and low to moderately present in researcher ratings (8–41%) for significant themes. Identification of negative self-beliefs in trauma was associated with a significantly higher likelihood of negative self-beliefs in voices [participants odds ratio (OR) 9.8; researchers OR 4.9]. Participants and researchers also reported many dependent links (80%, 66%, respectively), most frequently relational links (75%, 64%), followed by content (60%, 25%) and identity links (51%, 22%).ConclusionTrauma appears to be a strong shaping force for voice content and its psychological impact. The most common trauma–voice links involved the experience of cognitive-affective psychological threat, embodied in relational experiences. Trauma-induced mechanisms may be important intervention targets.
Traded and combined cooperative control of a smart wheelchair
Authors: Ech-Choudany Youssef , Grasse Régis , Stock Romuald , Horn Odile , Bourhis Guy 
Published: January 2022

AbstractThis article deals with a human–machine cooperative system for the control of a smart wheelchair for people with motor disabilities. The choice of a traded control mode is first argued. The paper then pursues two objectives. The first is to describe the design of the cooperative system by focusing on the dialogue and the interaction between the pilot and the robot. The second objective is to introduce a new cooperative mode. In this one, three features are proposed: two semi-autonomous features, a wall following and a doorway crossing, during which the user can intervene punctually to rectify a trajectory or a path, and an assisted mode where, conversely, the machine intervenes in a manual control to avoid obstacles. This mode of intervention of an entity, human or machine, supervising a movement controlled by the other is referred as “combined control.” Examples of scenarios exploiting the cooperative capabilities of the system are presented and discussed.
Evidence of sodium limitation in ants and termites in a Neotropical savanna
Authors: Clay Natalie A. , Shepard Donald B. , Garda Adrian A. , Mesquita Daniel O. , Vasconcellos Alexandre 
Published: January 2022

AbstractNutritional ecology of ropical ecosystems like Neotropical savannas, which are of high conservation concern, is understudied. Sodium is essential for heterotrophs but availability often falls short relative to plant consumer requirements. Savanna plant consumers like ants and termites should be sodium-limited due to high temperatures, nutrient-poor soils, and lack of oceanic sodium deposition. We tested the hypothesis that Neotropical savanna ants and termites are sodium-limited. Termites were tested by supplementing 0.25 m2plots with H2O (control), 0.1%, 0.5%, or 1.0% NaCl and measuring termite presence and artificial substrate mass loss after 1 week. Ants were tested by collecting ants that recruited to H2O (control), 0.1%, 0.5%, and 1.0% NaCl and 1.0%, 10%, and 20% sugar baits on paired diurnal–nocturnal transects. Termites were 16 times more likely to occur on 1% NaCl than H2O plots and wood-feeding termites were most frequent. However, the decomposition rate did not differ among treatments. Ant bait use increased with increasing NaCl concentration and 1% NaCl usage was similar to sugar bait usage. Ants were 3.7 times more active nocturnally than diurnally, but contrary to predictions bait type (water, sugar or NaCl) usage did not differ between day and night. Together, these results provide strong evidence of sodium limitation in Neotropical savannas.
Household clusters reveal household- and variant-specific properties of SARS-CoV-2
Authors: Buchholz Udo , Schulze-Wundling Kai , an der Heiden Matthias 
Published: January 2022

Abstract
It is unclear if – after symptom onset of a primary case of coronavirus disease-2019 (COVID-19) in a household – ensuing chains of transmissions among household members occur and if household epidemiology of COVID-19 is modified by the different circulating variants. We analysed data of 52 774 household clusters to investigate the day of symptom onset of ensuing cases in households relative to the symptom onset of the primary case within the household. Irrespective of cluster size or age of the primary case, 95% of all secondary household cases had symptom onset within 14 days after the symptom onset of the primary case. Stratification by variant showed that the mean interval from symptom onset of the primary case to the symptom onset of secondary cases decreased significantly from 4.8 days (wildtype) to 4.5 days (alpha) and 4.0 days (delta). Similarly, the cumulative proportion of 95% of secondary cases occurred within 14 days (wild type), 12 days (alpha) and 10 days (delta). Our findings suggest that during dominant delta circulation – apart from rare individual constellations – a 10-day household quarantine after symptom onset of the primary case is sufficient for household contacts who remain COVID-free.
Self- and informant-reported executive function in young adults operated for atrial or ventricular septal defects in childhood
Authors: El Dabagh Yasmin S. , Asschenfeldt Benjamin , Kelly Benjamin , Evald Lars , Hjortdal Vibeke E. 
Published: January 2022

AbstractBackground:Adults with simple congenital heart defects (CHD) have increased risk of neurodevelopmental challenges including executive dysfunction. It is unknown if the executive dysfunction is universal or if it is driven by dysfunction in specific clinical subscales and how it might affect psychosocial aspects of everyday life.Methods:The self-reported and informant-reported executive function of adults with an average age of 26 ± 5 (range 18–41) who underwent childhood surgery for atrial septal defects (n = 34) or ventricular septal defects (n = 32) and matched controls (n = 40) were evaluated using the Behavior Rating Inventory of Executive Functions - Adult version (BRIEF-A).Results:The CHD group reported having more executive dysfunction than controls in all BRIEF-A clinical subscales (p < 0.020) and more than their informants reported on their behalf (p < 0.006). The CHD group had received three times more special teaching (44% compared to 16%) and pedagogical psychological counselling (14% compared to none) and had a three times higher occurrence of psychiatric disorders than controls (33% compared to 11%). Lower educational levels and psychiatric disorders were associated with higher BRIEF-A scores (p < 0.03).Conclusions:Adults operated for septal defects in childhood report more challenges with all aspects of the executive functions than controls and more than relatives are aware of.
Entangled political histories of twentieth-century West Africa: The case of Guinean exile networks
Authors: Straussberger John 
Published: January 2022

AbstractFollowing independence in 1958, hundreds of Guinean soldiers, students, and politicians fled their home country in order to build an opposition to President Sékou Touré in exile. This article examines how these exiles built regional and global networks in order to effect political change. In turn, West African states sought to manage exiles in order to apply political pressure on regional rivals. Despite their liminality in a region increasingly dominated by national politics and international organizations, exiles were at the centre of political contestations surrounding citizenship, sovereignty, and human rights that emerged in the three decades following decolonization. Their history underscores the importance of regional frameworks in shaping the post-colonial order in West Africa.
Introduction to the symposium on institutional analysis, market processes, and interdisciplinary social science
Authors: D'Amico Daniel J. , Martin Adam G. 
Published: January 2022

Abstract
Heterodox economic approaches such as Austrian economics and market process analysis rely upon a less formalistic approach to rationality than neoclassical frameworks. We argue such looser formalism provides a unique opportunity for interdisciplinary engagement to investigating and understanding social institutions, outcomes and complex phenomenon. This introduction briefly summarizes the contents of this invited issue as effective examples of such interdisciplinarity.
Building and Raising Land: Mud and Vegetation Effects in Infilling Estuaries
Authors: Weisscher S. A. H. , Van den Hoven K. , Pierik H. J. , Kleinhans M. G. 
Published: January 2022

AbstractMany Holocene estuaries were infilled to form convergent, single‐channel systems, while others remained partially or wholly unfilled. This difference in the degree of infilling depends partly on the balance between fluvial and coastal sediment input and the hydrodynamics that can export sediment. However, it remains unclear to what degree this balance is tipped by mud supply and eco‐engineering vegetation, and by what planform patterns the infilling proceeds. This study aims to explore experimentally how mud and vegetation change the degree and process of infilling, elevate and merge bars above intertidal levels and affect the planform of estuaries. To this end, three experiments were conducted in the Metronome, a flume that tilts periodically to create tidal currents, wherein forced tidal asymmetry resulted in net importing estuaries. In the second and third experiments, mud was supplied and in the third experiment seedlings were released of three vegetation species with eco‐engineering traits at a laboratory scale. With only sand, the estuary fills sufficiently to form a multi‐channel pattern with intertidal bars. Both mud and vegetation settle on intertidal bars and on the fluvial bay‐head delta, thereby contributing to bar stabilization and further estuary infilling, pointing at effective strategies to keep up with future sea‐level rise. This reduces channel mobility and effectively narrows the summed subtidal channel width toward an ideally converging funnel shape. This seems especially effective where vegetation stabilizes the mud. The experiments suggest that a range of steady states exists between the end‐members of an unfilled and a completely infilled, ideal estuary.
Observed Landscape Responsiveness to Climate Forcing
Authors: Feldman Andrew F. , Short Gianotti Daniel J. , Trigo Isabel F. , Salvucci Guido D. , Entekhabi Dara 
Published: January 2022

AbstractClimate variability and change shift environmental conditions on global land surfaces, creating uncertainties in predicting hydrologic flows, crop yields, and land carbon uptake. Land surfaces can present varying degrees of inertia to atmospheric forcing variability (e.g., precipitation). This study asks: are regions with the most variable environmental forcing necessarily the regions with the largest land surface variability? Specifically, it seeks to determine why land surfaces show varying responsiveness to environmental forcing. The degree to which and the mechanisms for how landscapes modulate the forcing are evaluated using a decade‐long satellite observation record of Africa's diverse climates. Surface responsiveness is quantified using intra‐seasonal energy flux variability, based on the observed diurnal temperature amplitude. We map the responsiveness and analyze the underlying mechanisms over intra‐seasonal timescales (especially interstorms). We show that, at a location, land surface responsiveness is dependent on the soil moisture distribution and the nonlinear relationship between energy fluxes and soil moisture. Land surfaces with greater responsiveness to climate are those with soil moisture distributions that span the threshold between evaporation regimes and spend most of their time in the water‐limited regime. Consequently, surface responsiveness mechanisms drive land surface variability beyond high climatic variability. Since we find these results to hold from intra‐seasonal to interannual timescales, we expect that these responsive regions will be most vulnerable to long‐term shifts in climate forcing. The quantification of these phenomena and determination of their geographic distributions based on observations can help assess land surface models used to evaluate hydrologic consequences of climate change.
ADHD symptoms and diagnosis in adult preterms: systematic review, IPD meta-analysis, and register-linkage study
Authors: Robinson Rachel , Girchenko Polina , Pulakka Anna , Heinonen Kati , Lähdepuro Anna , Lahti-Pulkkinen Marius , Hovi Petteri , Tikanmäki Marjaana , Bartmann Peter , Lano Aulikki , Doyle Lex W. , Anderson Peter J. , Cheong Jeanie L. Y. , Darlow Brian A. , Woodward Lianne J. , Horwood L. John , Indredavik Marit S. , Evensen Kari Anne I. , Marlow Neil , Johnson Samantha , de Mendonca Marina Goulart , Kajantie Eero , Wolke Dieter , Räikkönen Katri 
Published: January 2022

Abstract
Background
This study examined differences in ADHD symptoms and diagnosis between preterm and term-born adults (≥18 years), and tested if ADHD is related to gestational age, birth weight, multiple births, or neonatal complications in preterm borns.

Methods
(1) A systematic review compared ADHD symptom self-reports and diagnosis between preterm and term-born adults published in PubMed, Web of Science, and PROQUEST until April 2021; (2) a one-stage Individual Participant Data(IPD) meta-analysis (n = 1385 preterm, n = 1633 term; born 1978–1995) examined differences in self-reported ADHD symptoms[age 18–36 years]; and (3) a population-based register-linkage study of all live births in Finland (01/01/1987–31/12/1998; n = 37538 preterm, n = 691,616 term) examined ADHD diagnosis risk in adulthood (≥18 years) until 31/12/2016.

Results
Systematic review results were conflicting. In the IPD meta-analysis, ADHD symptoms levels were similar across groups (mean z-score difference 0.00;95% confidence interval [95% CI] −0.07, 0.07). Whereas in the register-linkage study, adults born preterm had a higher relative risk (RR) for ADHD diagnosis compared to term controls (RR = 1.26, 95% CI 1.12, 1.41, p < 0.001). Among preterms, as gestation length (RR = 0.93, 95% CI 0.89, 0.97, p < 0.001) and SD birth weight z-score (RR = 0.88, 95% CI 0.80, 0.97, p < 0.001) increased, ADHD risk decreased.

Conclusions
While preterm adults may not report higher levels of ADHD symptoms, their risk of ADHD diagnosis in adulthood is higher.

Impact

Preterm-born adults do not self-report higher levels of ADHD symptoms, yet are more likely to receive an ADHD diagnosis in adulthood compared to term-borns.

Previous evidence has consisted of limited sample sizes of adults and used different methods with inconsistent findings. This study assessed adult self-reported symptoms across 8 harmonized cohorts and contrasted the findings with diagnosed ADHD in a population-based register-linkage study.

Preterm-born adults may not self-report increased ADHD symptoms. However, they have a higher risk of ADHD diagnosis, warranting preventive strategies and interventions to reduce the presentation of more severe ADHD symptomatology in adulthood.
Barriers and facilitators to changing bowel care practices after spinal cord injury: a Theoretical Domains Framework approach
Authors: Lucci Vera-Ellen M. , McKay Rhyann C. , McBride Christopher B. , McGrath Maureen S. , Willms Rhonda , Gainforth Heather L. , Claydon Victoria E. 
Published: January 2022

Abstract
Background
Improvement to autonomic processes such as bladder, bowel and sexual function are prioritised by individuals with spinal cord injury (SCI). Bowel care is associated with high levels of dissatisfaction and decreased quality of life. Despite dissatisfaction, 71% of individuals have not changed their bowel care routine for at least 5 years, highlighting a disconnect between dissatisfaction with bowel care and changing routines to optimise bowel care.

Objective
Using an integrated knowledge translation approach, we aimed to explore the barriers and facilitators to making changes to bowel care in individuals with SCI.

Methods
Our approach was guided by the Behaviour Change Wheel and used the Theoretical Domains Framework (TDF). Semi-structured interviews were conducted with individuals with SCI (n = 13, mean age 48.6 ± 13.1 years) and transcribed verbatim (duration 31.9 ± 7.1 min). Barriers and facilitators were extracted, deductively coded using TDF domains and inductively analysed for themes within domains.

Results
Changing bowel care after SCI was heavily influenced by four TDF domains: environmental context and resources (workplace flexibility, opportunity or circumstance, and access to resources); beliefs about consequences; social influences (perceived support and peer mentorship); and knowledge (knowledge of physiological processes and bowel care options). All intervention functions and policy categories were considered viable intervention options, with human (61%) and digital (33%) platforms preferred.

Conclusions
Modifying bowel care is a multi-factorial behaviour. These findings will support the systematic development and implementation of future interventions to both enable individuals with SCI to change their bowel care and to facilitate the optimisation of bowel care approaches.
MCMV-based vaccine vectors expressing full-length viral proteins provide long-term humoral immune protection upon a single-shot vaccination
Authors: Kim Yeonsu , Zheng Xiaoyan , Eschke Kathrin , Chaudhry M. Zeeshan , Bertoglio Federico , Tomić Adriana , Krmpotić Astrid , Hoffmann Markus , Bar-On Yotam , Boehme Julia , Bruder Dunja , Ebensen Thomas , Brunotte Linda , Ludwig Stephan , Messerle Martin , Guzman Carlos , Mandelboim Ofer , Hust Michael , Pöhlmann Stefan , Jonjić Stipan , Čičin-Šain Luka 
Published: January 2022

AbstractGlobal pandemics caused by influenza or coronaviruses cause severe disruptions to public health and lead to high morbidity and mortality. There remains a medical need for vaccines against these pathogens. CMV (cytomegalovirus) is a β-herpesvirus that induces uniquely robust immune responses in which remarkably large populations of antigen-specific CD8+ T cells are maintained for a lifetime. Hence, CMV has been proposed and investigated as a novel vaccine vector for expressing antigenic peptides or proteins to elicit protective cellular immune responses against numerous pathogens. We generated two recombinant murine CMV (MCMV) vaccine vectors expressing hemagglutinin (HA) of influenza A virus (MCMVHA) or the spike protein of severe acute respiratory syndrome coronavirus 2 (MCMVS). A single injection of MCMVs expressing either viral protein induced potent neutralizing antibody responses, which strengthened over time. Importantly, MCMVHA-vaccinated mice were protected from illness following challenge with the influenza virus, and we excluded that this protection was due to the effects of memory T cells. Conclusively, we show here that MCMV vectors induce not only long-term cellular immunity but also humoral responses that provide long-term immune protection against clinically relevant respiratory pathogens.
Injectable “nano-micron” combined gene-hydrogel microspheres for local treatment of osteoarthritis
Authors: Li Bin , Wang Fei , Hu Fangqiong , Ding Tao , Huang Ping , Xu Xing , Liang Jing , Li Changwei , Zhou Qi , Lu Min , Deng Lianfu , Guo Lei , Cui Wenguo 
Published: January 2022

AbstractSustained and controllable local gene therapy is a potential method for treating osteoarthritis (OA) through the delivery of therapeutic microRNAs (miRNAs) to targeted cells. However, direct injection of crude miRNAs for local gene therapy is limited due to its inadequate transfection efficiency, easy inactivation, and short half-life. Here, a multifunctional gene vector, arginine, histidine, and phenylalanine-modified generation 5 polyamidoamine (named G5-AHP), was employed to form G5-AHP/miR-140 nanoparticles by forming a complex with microRNA-140 (miR-140). Then, the nanoparticles were entrapped in hydrogel microspheres (MSs) to construct a “nano-micron” combined gene hydrogel to alleviate the degradation of articular cartilage. Monodisperse gelatin methacryloyl hydrogel MSs were produced under ultraviolet light using one-step innovative microfluidic technology. Evenly dispersed MSs showed better injectability in sustainable and matrix metalloproteinases (MMPs)-responsive degradation methods for local gene delivery. The G5-AHP/miR-140 nanoparticles released from the MSs exhibited high gene transfection efficacy and long-term bioactivity, facilitated endocytosis, and thus maintained the metabolic balance of cartilage matrix by promoting the expression of type II collagen and inhibiting the expression of a disintegrin and metalloproteinase with thrombospondin motifs-5 and MMP13 in chondrocytes. After injection of the “nano-micron” combined gene hydrogel into the articular cavity of the OA model, the gene hydrogel increased G5-AHP/miR-140 nanoparticle retention, prevented articular cartilage degeneration, and reduced osteophyte formation in a surgically induced mouse model of OA. The present study provides a novel cell-free approach to alleviate the progression of OA that shows potential for locally injected gene delivery systems.