bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Were you wearing underwear?” Stigma and fears around sexual violence: A narrative of stranger rape and considerations for mental health nurses when working with survivors
Authors: Welfare‐Wilson Alison , J Betty 
Published: August 2022

Accessible summaryWhat is known about the subject?

Although sexual violence is prevalent, incidents of stranger rape remain statistically uncommon.

Societal stigma and myths surrounding sexual violence are widespread.

An individual's experience in the immediate aftermath and beyond can be shaped by the perception/s of sexual violence which are held and expressed by those they come into contact with.

What this paper adds to existing knowledge?

This paper adds to the limited literature base and the population and practical‐knowledge gap around a specific form of sexual violence.

This paper also demonstrates the need for reflection and discussion in minimizing blame that can unconsciously be shifted onto survivors in the form of myths and stereotypical views of sexual violence.

What are the implications for practice?

Perceptions may be held around sexual violence, and by extension about the survivor, which may impede engagement and the building of trust within a therapeutic relationship.

Myths that are synonymous with rape and all forms of sexual violence can be held by professionals, and lead to blame, negative judgement and lack of empathy towards survivors.

Given the prevalence of sexual violence, this paper is applicable across all health and social care settings, and in particular mental health nursing professionals who may be more likely to meet people who have experienced sexual trauma.

AbstractIntroductionThis narrative illustrates the lived experience of a specific form of sexual violence (stranger rape) and its resulting implications as experienced by the second author, which is discussed under the following headings: your body as a crime scene, how lived experience compares to the myth of the ‘real rape’ and the wellbeing and health consequences arising from the experience. [Correction added on 5 September 2022, after first online publication: The preceding paragraph has been corrected in this version.]AimIn their capacity as mental health nurses, the authors invite readers to consider the spoken, or more likely unheard stories of sexual violence, which are unfortunately commonplace among those who access mental health services.Implications for PracticeFor professionals holding the privileged position of hearing these stories, there is a need to be reflective as to how fear, and personal or professionally held myths and stigmatizing views of sexual violence, and by extension views towards the survivor, are carried into therapeutic spaces, and the implications these can have. Practical suggestions as to how to discuss and manage disclosure of sexual violence in the context of trauma informed care are also provided.
Randomized clinical trial comparing outcomes after fentanyl or ketamine‐dexmedetomidine analgesia in thoracolumbar spinal surgery in dogs
Authors: Lovell Stephanie , Simon Bradley , Boudreau Elizabeth C. , Mankin Joseph , Jeffery Nicholas 
Published: August 2022

AbstractBackgroundOpioids are widely used for perioperative pain control in dogs undergoing spinal surgery, but alternatives may be required because data suggest that opioids exacerbate inflammation in the injured spinal cord and veterinary access to opioids may become more restricted in the future.ObjectivesTo compare recovery of ambulation and other functions between spinal cord‐injured dogs receiving peri‐operative fentanyl and those receiving a ketamine‐dexmedetomidine combination.AnimalsA total of 102 client‐owned dogs undergoing decompressive surgery for thoracolumbar intervertebral disc herniation.MethodsRandomized clinical trial. Dogs were randomized 1:1 to fentanyl or a ketamine‐dexmedetomidine combination for intra and postoperative analgesia. Primary outcome was time to recovery of ambulation; secondary outcomes were the postoperative Colorado Acute Pain Scale, the short‐form Glasgow Composite Measure Pain Scale, time to recovery of voluntary urination and time to unassisted eating.ResultsNo difference was found in time to recovery of ambulation between groups (adjusted sub‐hazard ratio, 0.83; 95% confidence interval [CI], 0.55‐1.24; P = .36) or in pain scores (Colorado: χ2 = 14.74; P = .32; Glasgow: χ2 = 6.61; P = .76). Differences in time to recovery of eating and urination were small but favored ketamine‐dexmedetomidine (adjusted odds ratios, 3.31; 95% CI, 1.53‐7.16; P = .002 and 2.43; 95% CI, 1.00‐5.96; P = .05, respectively).Conclusions and Clinical ImportanceThere was no evidence that, at the doses used, fentanyl impaired ambulatory outcome after surgery for thoracolumbar intervertebral disc herniation in dogs. Pain control appeared similar between groups. Secondary outcomes suggested minor benefits associated with ketamine‐dexmedetomidine. The ketamine‐dexmedetomidine combination appears to be a reasonable alternative to peri‐operative opioids.
Five‐year outcomes in liver transplant patients receiving everolimus with or without a calcineurin inhibitor: Results from the CERTITUDE study
Authors: Saliba Faouzi , Duvoux Christophe , Dharancy Sébastien , Dumortier Jérôme , Calmus Yvon , Gugenheim Jean , Kamar Nassim , Salamé Ephrem , Neau‐Cransac Martine , Vanlemmens Claire , Durand François , Pageaux Georges‐Philippe , Hardwigsen Jean , Benkhatar Yasmina , Derquenne François , Conti Filomena 
Published: August 2022

AbstractBackground and AimsTo report 5‐year outcomes of the CERTITUDE study.MethodsAn observational study in patients with liver transplantation (LTx) compared the long‐term impact of immunosuppression (with/without a calcineurin inhibitor) on renal function, cancers, major cardiovascular events (MACEs) and other safety parameters. All patients completing the 6‐month SIMCER study were recruited and analysed according to treatment received at randomization and actual treatment received during the follow‐up.ResultsOf the 143 enrolled patients, 119 completed the 5‐year follow‐up (everolimus [EVR], n = 55; tacrolimus [TAC], n = 64). The mean absolute change in estimated glomerular filtration rate was not statistically different between both groups (TAC, −15.53 ml/min/1.73 m2 and EVR, –14.56 ml/min/1.73 m2). In the treatment subgroups based on actual treatment received, renal function was preserved better in the EVR subgroup compared with other subgroups (p = .051). Treated biopsy‐proven acute rejection was higher in the EVR group (15.4% vs. 6.4%); however, the majority of events were mild in severity. MACE occurred in 9.2% vs. 14.1% of patients in the EVR and TAC groups respectively (p = .370). De novo cancer was reported in 14 and 5 patients in EVR and TAC groups respectively. Hepatocellular carcinoma (HCC) recurrence was observed in the TAC group alone (n = 4). Adverse events and treatment discontinuation owing to an adverse event were higher in the EVR group.ConclusionsThe CERTITUDE study demonstrated that EVR‐ and TAC‐based regimens have comparable efficacy, safety and tolerability up to 5 years post‐LTx.
Traffic signal optimization for partially observable traffic system and low penetration rate of connected vehicles
Authors: Zhang Zhao , Guo Mengdi , Fu Daocheng , Mo Lei , Zhang Siyao 
Published: August 2022

AbstractObservability and controllability are two critical requirements for a partially observable transportation system. This paper proposes a stepwise signal optimization framework with connected vehicle (CV) data as input to solve both challenges. First, a Bayesian deduction method based on low‐penetration CV data is established to estimate the traffic volume. Thereafter, an offline signal optimization model is constructed to simultaneously optimize the flexible lane settings and signal timings, which are set as the prior information for the third step. In the third step, an online deep recurrent Q‐learning (DRQN) signal optimization model dynamically adjusts signal settings based on real‐time traffic information. Numerical experiments demonstrate that the model outperforms the actuated control, the online DQRN model without offline filter, and the back‐pressure model by 9%–66% and 7%–29% in two networks. This study innovatively combines traffic state estimation and traffic signal control as an integrated process. It contributes to an improved understanding of traffic control in a CV environment and lays a solid foundation for future traffic control strategies.
Morphometrics of mammal‐eating killer whales from drone photogrammetry, with comparison to sympatric fish‐eating killer whales in the eastern North Pacific
Authors: Kotik Chloe , Durban John W. , Fearnbach Holly , Barrett‐Lennard Lance G. 
Published: August 2022

AbstractAerial photogrammetry has provided increased power for monitoring the health of individuals in the endangered population of Southern Resident killer whales (SRKW,Orcinus orca) in the eastern North Pacific. These data have shown evidence of nutritional stress, with individual growth and body condition correlating with the availability of their primary prey, Chinook salmon (Oncorhynchus tshawytscha). We used drones to derive similar but novel photogrammetry measurements from a sympatric population of mammal‐eating Bigg's killer whales (BKWs) that has been increasing in abundance in recent decades. From 2014 to 2019 we photographed 95 individual BKWs in Canadian waters off Vancouver Island and US waters in the Salish Sea; we estimated asymptotic lengths of 6.4 m for adult females and 7.3 m for adult males, both longer than corresponding length estimates for SRKWs. As a proxy for body condition, we measured head width at a standardized distance behind the blowhole, expressed as proportion of the length between the blowhole and dorsal fin, and estimated that on average, all age/sex classes of BKWs were more robust than corresponding classes of SRKWs. These differences likely reflect divergent adaptive selection in these prey‐specialist ecotypes, but may also partially indicate recent impacts of differential prey availability.
Chloroplast‐localized PITP7 is essential for plant growth and photosynthetic function in Arabidopsis
Authors: Kim Eun‐Ha , Poudyal Roshan Sharma , Lee Kyeong‐Ryeol , Yu Hami , Gi Eunji , Kim Hyun Uk 
Published: August 2022

AbstractRecent studies of chloroplast‐localized Sec14‐like protein (CPSFL1, also known as phosphatidylinositol transfer protein 7, PITP7) showed that CPSFL1 is necessary for photoautotropic growth and chloroplast vesicle formation in Arabidopsis (Arabidopsis thaliana). Here, we investigated the functional roles of CPSFL1/PITP7 using twoA. thalianamutants carrying a putative null allele (pitp7‐1) and a weak allele (pitp7‐2), respectively.PITP7transcripts were undetectable inpitp7‐1and less abundant inpitp7‐2than in the wild‐type (WT). The severity of mutant phenotypes, such as plant developmental abnormalities, levels of plastoquinone‐9 (PQ‐9) and chlorophylls, photosynthetic protein complexes, and photosynthetic performance, were well related toPITP7transcript levels. Thepitp7‐1mutation was seedling lethal and was associated with significantly lower levels of PQ‐9 and major photosynthetic proteins.pitp7‐2plants showed greater susceptibility to high‐intensity light stress than the WT, attributable to defects in nonphotochemical quenching and photosynthetic electron transport. PITP7 is specifically bound to phosphatidylinositol phosphates (PIPs) in lipid‐binding assays in vitro, and the point mutations R82, H125, E162, or K233 reduced the binding affinity of PITP7 to PIPs. Further, constitutive expression of PITP7H125Qor PITP7E162Kinpitp7‐1homozygous plants restored autotrophic growth in soil but without fully complementing the mutant phenotypes. Consistent with a previous study, our results demonstrate that PITP7 is essential for plant development, particularly the accumulation of PQ‐9 and photosynthetic complexes. We propose a possible role for PITP7 in membrane trafficking of hydrophobic ligands such as PQ‐9 and carotenoids through chloroplast vesicle formation or direct binding involving PIPs.
An interdisciplinary synthesis of research on understanding and promoting well‐doing
Authors: Lieder Falk , Prentice Mike , Corwin‐Renner Emily R. 
Published: August 2022

AbstractPeople's intentional pursuit of prosocial goals and values (i.e., well‐doing) is critical to the flourishing of humanity in the long run. Understanding and promoting well‐doing is a shared goal across many fields inside and outside of social and personality psychology. Several of these fields are (partially) disconnected from each other and could benefit from more integration of existing knowledge, interdisciplinary collaboration, and cross‐fertilization. To foster the transfer and integration of knowledge across these different fields, we provide a brief overview with pointers to some key articles from each field, highlight connections, and introduce an integrative model of the psychological mechanisms of well‐doing. We identify some gaps in the current understanding of well‐doing, such as the paucity of research on well‐doing with large and long‐lasting positive consequences. Building on this analysis, we identify opportunities for high‐impact research on well‐doing in social and personality psychology, such as understanding and promoting the effective pursuit of highly impactful altruistic goals.
Parallel analysis of RNA ends reveals global microRNA‐mediated target RNA cleavage in maize
Authors: He Juan , Xu Chi , You Chenjiang , Mo Beixin , Chen Xuemei , Gao Lei , Liu Lin 
Published: August 2022

SUMMARYMicroRNAs (miRNAs) are endogenous 20–24‐nucleotide non‐coding RNAs that play important regulatory roles in many biological processes in eukaryotes. miRNAs modulate the expression of target genes at the post‐transcriptional level by transcript cleavage or translational inhibition. The identification of miRNA target genes has been extensively investigated in Arabidopsis and rice, but an in‐depth global analysis of miRNA‐mediated target regulation is still lacking in maize. Here, we report a transcriptome‐wide identification of miRNA targets by analyzing parallel analysis of RNA ends (PARE) datasets derived from nine different tissues at five developmental stages of the maize (Zea mays L.) B73 cultivar. In total, 246 targets corresponding to 60 miRNAs from 25 families were identified, including transcription factors and other genes. In addition, PARE analysis revealed that miRNAs guide specific target transcript cleavage in a tissue‐preferential manner. Primary transcripts of MIR159c and MIR169e were found to be cleaved by mature miR159 and miR169, respectively, indicating a negative‐feedback regulatory mechanism in miRNA biogenesis. Moreover, several miRNA‐target gene pairs involved in seed germination were identified and experimentally validated. Our PARE analyses generated a wide and detailed miRNA‐target interaction atlas, which provides a valuable resource for investigating the roles of miRNAs and their targets in maize.
Relationship Between Age and Running Kinematics in Female Recreational Runners
Authors: Hamilton Heather M. , Kakar Rumit Singh 
Published: August 2022

Sex-based analyses are important when studying running kinematics. Females experience a unique aging process and demonstrate differences in running biomechanics from males. The purpose was to determine the relationship between age and running kinematics in female runners. Forty-six female runners (18–65 y) ran at self-selected jogging and maximal speed on a treadmill. Lower-extremity joint kinematics were calculated, and 2 principal component analyses (jogging speed and maximal speed) were performed from kinematic variables. Regression was used to examine the relationship between age and identified components, and between age and the variables with the highest loadings within these components. For jogging speed, there was a positive relationship between age and ankle varus at initial contact and a negative relationship between age and peak eversion, hip adduction, knee flexion, dorsiflexion, and hip adduction at initial contact (Ps < .05). For maximal speed, initial contact ankle frontal plane angle became more positive with age, and there was a negative relationship with age and peak eversion, dorsiflexion and knee flexion, and knee flexion and hip adduction at initial contact (Ps < .05). Primarily distal joint angles decreased with increasing age in female recreational runners at self-selected running speeds.
Geodesics in generalised Ellis–Bronnikov spacetime embedded in warped 5D background
Authors: Sharma Vivek , Ghosh Suman 
Published: August 2022

AbstractWe study the particle trajectories in the recently proposed five dimensional warped (generalized) Ellis–Bronnikov spacetime (5D-WGEB) (which does not require exotic matter) as well as it’s four dimensional counterpart (4D-GEB) in detail and conduct a comparative study. Analytical approach provides conditions which determines three types of trajectories (trapped, returning and crossing) for both 4D and 5D spacetimes. Notably in 5D geometry existence of trapped trajectories become highly sensitive to the initial conditions. We have solved the timelike geodesic equations numerically and presented the trajectories graphically along with corresponding geodesic potentials. We thus distinguished the roles of the so-called wormhole parameter and the warping factor regarding their effects on the trajectories and embedding as such. Interestingly, the 5D-WGEB model shows the localization of massive particles around the location of the brane for growing warp factor and runaway trajectories for decaying warp factor.
Edge-computing-driven Internet of Things: A Survey
Authors: Kong Linghe , Tan Jinlin , Huang Junqin , Chen Guihai , Wang Shuaitian , Jin Xi , Zeng Peng , Khan Muhammad , Das Sajal K. 
Published: August 2022

The Internet of Things (IoT) is impacting the world’s connectivity landscape. More and more IoT devices are connected, bringing many benefits to our daily lives. However, the influx of IoT devices poses non-trivial challenges for the existing cloud-based computing paradigm. In the cloud-based architecture, a large amount of IoT data is transferred to the cloud for data management, analysis, and decision making. It could not only cause a heavy workload on the cloud but also result in unacceptable network latency, ultimately undermining the benefits of cloud-based computing. To address these challenges, researchers are looking for new computing models for the IoT. Edge computing, a new decentralized computing model, is valued by more and more researchers in academia and industry. The main idea of edge computing is placing data processing in near-edge devices instead of remote cloud servers. It is promising to build more scalable, low-latency IoT systems. Many studies have been proposed on edge computing and IoT, but a comprehensive survey of this crossover area is still lacking.
In this survey, we first introduce the impact of edge computing on the development of IoT and point out why edge computing is more suitable for IoT than other computing paradigms. Then, we analyze the necessity of systematical investigation on the edge-computing-driven IoT (ECDriven-IoT) and summarize new challenges occurring in ECDriven-IoT. We categorize recent advances from bottom to top, covering six aspects of ECDriven-IoT. Finally, we conclude lessons learned and propose some challenging
Hydrogen Gas Inhalation Attenuates Acute Impulse Noise Trauma: A Preclinical In Vivo Study
Authors: Videhult Pierre Pernilla , Fransson Anette , Kisiel Marta A. , Laurell Göran 
Published: August 2022

Objective: Molecular hydrogen (H2) has shown therapeutic potential in several oxidative stress-related conditions in humans, is well-tolerated, and is easily administered via inhalation.The aim of this preclinical in vivo study was to investigate whether impulse noise trauma can be prevented by H2 when inhaled immediately after impulse noise exposure. Methods: Guinea pigs (n = 26) were subjected to impulse noise (n = 400; 156 dB SPL; 0.33/s; n = 11; the Noise group), to impulse noise immediately followed by H2 inhalation (2 mol%; 500 ml/min; 1 hour; n = 10; the Noise + H2 group), or to H2 inhalation (n = 5; the H2 group). The acoustically evoked ABR threshold at 3.15, 6.30, 12.5, 20.0, and 30.0 kHz was assessed before and 4 days after impulse noise and/or H2 exposure. The cochleae were harvested after the final ABR assessment for quantification of hair cells. Results: Noise exposure caused ABR threshold elevations at all frequencies (median 35, 35, 30, 35, and 35 dB SPL, the Noise group; 20, 25, 10, 13, and 20 dB SPL, the Noise + H2 group; P < .05) but significantly less so in the Noise + H2 group ( P < .05). Outer hair cell (OHC) loss was in the apical, mid, and basal regions 8.8%, 53%, and 14% in the Noise group and 3.5%, 22%, and 1.2% in the Noise + H2 group. The corresponding inner hair cell (IHC) loss was 0.1%, 14%, and 3.5% in the Noise group and 0%, 2.8%, and 0% in the Noise + H2 group. The difference between the groups was significant in the basal region for OHCs ( P = .003) and apical ( P = .033) and basal ( P = .048) regions for IHCs. Conclusions: Acute acoustic trauma can be reduced by H2 when inhaled immediately after impulse noise exposure.
Examination of Pandemic Awareness, Death Anxiety, and Spiritual Well-Being in Elderly Individuals
Authors: Özer Özlem , Özkan Okan , Büyükşirin Bilge 
Published: August 2022

This study aimed to examine the relationships between the variables of pandemic awareness, death anxiety, and spiritual well-being and reveal whether the participants’ perceptions of pandemic awareness, death anxiety, and spiritual well-being differed according to various sociodemographic characteristics. The study population is comprised of individuals aged 65 years and over in Edirne, Turkey. The data obtained from 449 people in the study were analyzed using various statistical methods. According to the results of the regression analysis performed in the study, the increase in the participants’ pandemic awareness was found to reduce their death anxiety and increase their spiritual well-being statistically. Moreover, the increase in the participants’ death anxiety statistically reduced their spiritual well-being.