bluuebunny/crossref_metadata_2025_split huggingface dataset:
Water Quality Status Based on Pollution Index to Meet The Needs of Sanitary Hygienic Water For Communities Around Lake Sentani In Jayapura Regency
Authors: Suhartawan Bambang , Alfonso Alfred B. , Daawia Daawia 
Published: October 2022

Water is one of the most important elements on earth. Water is needed by all living things, both humans, plants and animals. Consuming clean and sanitary water is absolutely necessary to avoid unwanted negative impacts. This research was conducted in February 2022 and aims to determine the status of the water quality of Lake Sentani, Jayapura Regency based on the pollution index according to the hygienic and sanitary water quality standards according to the Regulation of the Minister of Health of the Republic of Indonesia Number: 32 of 2017 concerning Environmental health quality standards and water health requirements for sanitation hygiene needs, swimming pools, solus per agua and public baths. The study used 15 (fifteen) water pollution parameters, namely: physical parameters (turbidity, color, TDS and temperature), and chemical parameters (pH, iron, fluoride, hardness, manganese, nitrate, cyanide, detergent and total pesticides) as well as biological parameters. (total coliforms). The sample in this study was taken from 5 (five) sample points (research stations) namely the mouths of the Haway, Yabawi, Hobay and Kamwalker rivers which are the inlet of Lake Sentani and the headwaters of the Jaifuri river which is the outlet. The results showed that at stations 1, 2, 3, 4 and 5, the pollution index (PIj) was 4.07; 3.10; 2.30; 3.75 and 3.88, all of which are based on the Regulation of the Minister of Health of the Republic of Indonesia Number: 32 of 2017 especially environmental health quality standards and water health requirements for sanitation hygiene purposes, are in the range of values of 1 PIj 5 with lightly polluted status. Thus it can be concluded that the water quality status of Lake Sentani based on the pollution index method is in the lightly polluted category.
Antibody Responses Following Covid-19 Vaccine in Pregnant Women- A Prospective Study
Authors: Hamayun Zunaira , Javaid Usman , Ahmed Rizwan , Shehzad Khurram , Imam Gul Pari 
Published: October 2022

Objective: To assess the antibody responses and adverse effects of sinopharm vaccine in pregnant women.Study Design: A prospective cohort study.Place and Duration of Study: The study was conducted in the Gynaecology Department of Ibn-e-Siena HospitalMultan, Independent Hospital Faisalabad and Mayo Hospital Lahore from January 2021 to January 2022.Materials and Methods: A total of 90 women were included in the study who were administered Sinopharm.Three out of ninety (3.3%) women received shots in 1st trimester, 56/90 (62%) in 2nd trimester and 31/90 (34%) in third trimester. Enzyme-linked immunosorbent assay (ELISA) was used to measure SARS-CoV-2 receptorbinding domain (RBD) specific total antibodies and angiotensin-converting enzyme 2 (ACE2) blockingantibodies. The adverse effects on the mother and fetus were evaluated after the delivery.Results: The administration of the sinopharm vaccine showed no adverse effects or pregnancy complicationssuch as congenital anomalies, miscarriage, preterm delivery, thrombotic events, fetal death or hypertensivedisorders. SARS-CoV-2 specific total antibodies were found in 57/90 (63%) women at the time recruitment(when receiving 1st dose); thus they were considered to be previously infected. After the second dose, allwomen were seroconverted. Significantly high levels of RBD binding antibodies and ACE2 blocking antibodieswere observed in previously infected women after administration of the second dose compared to uninfectedindividuals.Conclusion: The Sinopharm vaccine showed positive results in pregnant women and induced highseroconversion rates and ACE2 blocking antibodies in second and third trimesters.
How to cite this: Hamayun Z, Javaid U, Ahmed R, Shehzad K, Gul PI. Antibody Responses Following Covid-19 Vaccine in Pregnant Women- A Prospective Study. Life and Science. 2022; 3(4): 196-199. doi: http://doi.org/10.37185/LnS.1.1.273
Generalized derivations acting on multilinear polynomials as a Jordan homomorphisms
Authors: Tiwari S. K. , Prajapati B. 
Published: October 2022

UDC 512.5
Let

R

be a prime ring whose characteristic is not equal to

2
,

let

U

be the Utumi quotient ring of

R
,

and let

C

be the extended centroid of

R
.

Also let

G

and

H

be two generalized derivations on

R

and let

f

(

x
1

,
…
,

x
n

)

be a noncentral multilinear polynomial over

C
.

If

G

(
H
(

u
2

)
)

=

(
H
(
u
)
)

2

for all

u
=
f

(

r
1

,
…
,

r
n

)

,

r
1

,
…
,

r
n

∈
R
,

then one of the following holds:
1)

H
=
0
;

2) there exists

λ
∈
C

such that

G

(
x
)

=
H

(
x
)

=
λ
x

for all

x
∈
R
;

3) there exist

λ
∈
C

and

a
∈
U

such that

H

(
x
)

=
λ
x

and

G

(
x
)

=

[
a
,
x
]

+
λ
x

for all

x
∈
R

and

f

(

x
1

,
…
,

x
n

)

2

is central-valued on

R
.
Factors on development and severity of acute radiodermatitis: prospective single-center study
Authors: ALTINIŞIK İNAN Gonca , ARSLAN Alaettin , ARAL İpek Pınar , AYTAÇ ARSLAN Suheyla 
Published: October 2022

Aim: Although prior literature has examined the treatment and patient-associated factors affecting the development and severity of acute radiodermatitis, there are relatively few prospective studies evaluating both. This study was prospectively designed to evaluate factors affecting the development and extent of radiation-induced acute skin toxicity called radiodermatitis (RD).
Material and Method: A total of 63 patients who underwent radiotherapy (RT) in Ankara Atatürk Research and Education Hospital between July 2017 and October 2018 were evaluated. Patients’ demographic status, disease/treatment details, hemoglobin, ferritin, folic acid, Vit B12, and hemoglobin A1c values were recorded. The development and grade of RD were evaluated weekly by the same radiation oncologist using the Radiation Therapy Oncology Group (RTOG) radiation toxicity guideline.
Results: There was no significant relationship between the development of any degree of RD and gender, concomitant chemotherapy (CT), pre-RT CT, comorbid disease, RT technique and blood parameters (Hb, Hba1c, ferritin, folic acid and B12). The development of grade 2-3 RD was significantly affected by the number of operations (p=0.032) and total dose of RT (p=0.008). In patients with grade 2/3 RD, the RT dose at which RD first appeared was 20 Gy (range, 14-36); in patients with grade 1 RD, this value was 32 Gy (range, 16-56) (p=0.018).
Conclusion: There is no significant relationship between the development of acute radiodermatitis and Hba1c, hemoglobin, ferritin, B12 and folic acid levels. There was a significant correlation between grade of RD and repeated surgery, increase in total RT dose and early onset of RD.
Correcting Stellar Flare Frequency Distributions Detected by TESS and Kepler
Authors: Gao 高 Dong-Yang 东洋 , Liu 刘 Hui-Gen 慧根 , Yang 杨 Ming 明 , Zhou 周 Ji-Lin 济林 
Published: October 2022

Abstract
The habitability of planets is closely connected with stellar activity, mainly the frequency of flares and the distribution of flare energy. Kepler and TESS find many flaring stars via precise time-domain photometric data, and the frequency and energy distribution of stellar flares on different types of stars are studied statistically. However, the completeness and observational bias of detected flare events from different missions (e.g., Kepler and TESS) vary a lot. We use a unified data processing and detection method for flare events based on the light curves from Kepler and TESS. Then we perform injection and recovery tests in the original light curve of each star for each flare event to correct the completeness and energy of flares. Three samples of flaring stars are selected from Kepler and TESS, with rotation periods from 1 to ∼5 days. Adopting a hot-blackbody assumption, our results show that the cumulative flare frequency distributions (FFDs) of the same stars in Kepler and TESS bands tend to be consistent after correction, revealing a more natural flaring frequency and energy distribution. Our results also extend the low-energy limit in cumulative FFD fitting to 1031.5−33 erg on different types of stars. For solar-type stars, the average power-law index of cumulative FFD (α
cum) is −0.84, which indicates that low-energy flares contribute less to the total flare energy. With a piecewise correlation between α
cum and T
eff, α
cum first rises from M2 to K1 stars, then slightly decreases for stars hotter than K1.
Characterizing and Mitigating Telluric Absorption in Precise Radial Velocities. II. A Study of an M2-type Star
Authors: Latouf Natasha , Wang Sharon Xuesong , Cale Bryson , Plavchan Peter 
Published: October 2022

Abstract
Telluric absorption lines impact the measuring of precise radial velocities (RVs) from high-resolution ground-based spectrographs. In this paper, we simulate the dependence of this impact on stellar spectral type and extend the work of the first paper in this series, which studied a G-type star, to a synthetic M-dwarf star. We quantify the bias in precise RV measurements in the visible and near-infrared (NIR) from the presence of tellurics in a simulated set of observations. We find that M-dwarf RVs are more impacted by tellurics compared to G-type stars. Specifically, for an M-dwarf star, tellurics can induce RV errors of up to 16 cm s−1 in the red optical and in excess of 220 cm s−1 in the NIR. For a G dwarf, the comparable RV systematics are 3 cm s−1 in the red optical and 240 cm s−1 in the NIR. We attribute this relative increase for M-dwarf stars to the increased concordance in wavelength between telluric lines and stellar Doppler information content. We compare the results of our simulation to data collected for Barnard’s star from the iSHELL spectrograph at the NASA Infrared Telescope Facility. This study was conducted as a follow-up to the NASA probe mission concept study EarthFinder.
The Prompt Emission of GRB 130518A and the Study of Its Outflow through Hybrid Jet Models
Authors: Siddique Iqra , Sajjad Saeeda , Motiwala Khadeejah 
Published: October 2022

Abstract
The nature of the prompt emission mechanism in gamma-ray bursts (GRBs) remains uncertain to date. This question is also tied to the composition of the jet: thermal, Poynting flux dominated or hybrid with both types of components. In this work, we aim to study these questions in the context of GRB 130518A. By analysing its prompt emission data from the Fermi Gamma-ray Burst Monitor (GBM) and Large Area Telescope (LAT), we find that the time-integrated spectrum has a nonthermal component along with a subdominant blackbody component. We use these results to study the properties of the jet in various scenarios through the frameworks developed by Hascoët et al. and Gao & Zhang. Both frameworks exclude the pure fireball model for this GRB. In all other cases, the initial magnetic fraction is greater than the thermal fraction. For small launching radii of the jet, the favored nonthermal emission process is internal shocks. Magnetic reconnection seems likely only for very large initial radii.
Can the Violent Merger of White Dwarfs Explain the Slowest Declining Type Ia Supernova SN 2011aa?
Authors: Dutta Anirban , Anupama G. C. , Chakradhari Nand Kumar , Sahu D. K. 
Published: October 2022

Abstract
We present optical observations and Monte Carlo radiative transfer modeling of the Type Ia supernova (SN Ia) SN 2011aa. With a Δm
15(B) of 0.59 ± 0.07 mag and a peak magnitude M
B of −19.30 ± 0.27 mag, SN 2011aa has the slowest decline rate among SNe Ia. The secondary maximum in the I band is absent or as equally bright as the primary maximum. The velocity of C ii is lower than the velocity of Si ii. This indicates either the presence of C at lower velocities than Si or a line-of-sight effect. Application of Arnett’s radiation diffusion model to the bolometric light curve indicates a massive ejecta M
ej 1.8–2.6 M
⊙. The slow decline rate and large ejecta mass, with a normal peak magnitude, are well explained by a double degenerate, violent merger explosion model. The synthetic spectra and light curves generated with SEDONA considering a violent merger density profile match the observations.
Creating a Primary Care Track in Prelicensure Nursing Education
Authors: Hawkins Janice E. , Wiles Lynn L. , Martin Jamela , Tremblay Beth , Higgins Karen , Mahoney Ingrid 
Published: October 2022

Background:
RNs practicing in primary care (PC) increase access to health care and contribute to better patient outcomes and cost savings, yet undergraduate nursing education traditionally focuses on disease-oriented care. This article describes a curricular track for infusing PC prelicensure programs.

Method:
PC content is threaded across four semesters with targeted assignments and clinical experiences. Providing clinical immersion experiences with practicing RNs as preceptors in community and PC settings is a key component of this initiative.

Results:
Student feedback has been favorable. Students stated they gained insight to the role of RNs in PC through class assignments and clinical rotations. Graduating seniors were offered employment in PC settings where they completed their practicum clinical rotations.

Conclusion:

The PC track contributes to building a nursing workforce to meet health care demands and promote health equity. Nurse educators interested in infusing PC content throughout the curriculum can adapt this model for all student populations.

[
J Nurs Educ
. 2023;62(3):171-174.]
Échos des chansons enfantines dans les livres pour enfants au xixe siècle en France
Authors: Manson Michel 
Published: October 2022

Résumé : Après avoir, dans des recherches antérieures, décrit les étapes de transformations des chansons de la culture populaire ou savante en chansons enfantines publiées dans les livres destinés à l’enfance, il s’agit dans cet article de chercher dans les autres livres pour enfants les traces, les échos que ces chansons enfantines ont pu avoir. Une analyse quantitative d’un corpus de près de six cents titres donnant près d’une centaine de titres avec de tels échos, nous permet de commencer à comprendre les raisons éditoriales et idéologiques permettant à cette culture orale chantée de pénétrer dans les livres pour enfants. Les passages retenus sont alors analysés pour montrer la mise en situation des chansons enfantines dans les histoires racontées par nos auteurs. Les rondes chantées, les berceuses, les formulettes et les chansons donnent lieu à des mises en scène différentes. Pour une analyse plus fine de l’apport des auteurs retenus, plusieurs exemples ont été choisis : deux formulettes, deux berceuses et la chanson bien connue des Trois jeunes tambours. Le recours aux recherches des folkloristes permet de mieux situer cet apport dans ce passage de la culture orale à la culture littéraire.
École buissonnière et ensauvagement de la raison graphique
Authors: Lanot Simon 
Published: October 2022

« En sortant de l’école » (1946) de Jacques Prévert et Joseph Kosma est chantée dans les écoles et les foyers. Le texte qui raconte la fugue d’enfants faisant l’école buissonnière est une mise en pièces de la culture scolaire : il compose, à partir d’éléments hétéroclites du capital littératien, un collage surréaliste mêlant des morceaux de livres, racontant un voyage merveilleux, cosmique, « tout autour de la terre ». La dimension orale du poème s’articule à la raison graphique qu’elle ne nie pas, mais qu’elle contribue à ensauvager. En confrontant le texte à l’hypothèse de l’ethnocritique qui interroge une homologie possible entre rite et poème, nous lirons « En sortant de l’école » comme un rite de passage à l’âge adulte, rite que le poème subvertit en douceur.
Aflatoxin G1 exposure altered the expression of BDNF and GFAP, histopathological of brain tissue, and oxidative stress factors in male rats
Authors: Zamir-Nasta Toraj , Abbasi Ardeshir , Kakebaraie Seyran , Ahmadi Arash , Pazhouhi Mona , Jalili Cyrus 
Published: October 2022

Background and purpose:
Aflatoxins are highly toxic compounds that can cause acute and chronic toxicity in humans and animals. This study aimed to evaluate the expression of BDNF and GFAP, histopathological changes, and oxidative stress factors in brain tissue exposed to aflatoxin G1 (AFG1) in male rats.

Experimental approach:
Twenty-eight male Wistar rats were used. Animals were randomly divided into 4 groups of 7 each. The control group received 0.2 mL of corn oil and the treatment groups were exposed to AFG1 (2 mg/kg) intra-peritoneally for 15, 28, and 45 days. The tissue was used for histopathological studies, and the level of TAC, SOD, and MDA, and the expression of BDNF and GFAP genes were evaluated.

Findings/Results:
Real-time PCR results showed that AFG1 increased GFAP expression and decreased BDNF expression in AFG1-treated groups compared to the control group. The tissue level of TAC and SOD over time in the groups receiving AFG1 significantly decreased and the tissue level of MDA increased compared to the control group. Histopathological results showed that AFG1 can cause cell necrosis, a reduction of the normal cells number in the hippocampal region of CA1, cerebral edema, shrinkage of nerve cells, formation of space around neuroglia, and diffusion of gliosis in the cerebral cortex after 45 days.

Conclusion and implication:
AFG1, by causing pathological complications in cortical tissue, was able to affect the exacerbation of nerve tissue damage and thus pave the way for future neurological diseases.
Sex differences in acetylcholinesterase modulation during spatial and fear memory extinction in the amygdala; an animal study in the single prolonged stress model of PTSD
Authors: Mohammadi-Farani Ahmad , Farhangian Sajad , Shirooie Samira 
Published: October 2022

Background and purpose:
Men and women show different reactions to trauma and that is believed to be the reason behind the higher prevalence of post-traumatic stress disorder (PTSD) in women. Cholinergic signaling has long been known to be involved in the processing of fear-related information and the amygdala is a critical center for fear modulation. The main goal of the current research was to find (a) whether trauma results in different learning/extinction of fear or spatial-related information among male and female rats and (b) if trauma is associated with different acetylcholinesterase (AchE) activity in the amygdala.

Experimental approach:
We used single prolonged stress (SPS) as a PTSD model in this study. Normal and SPS animals of both sexes were tested in contextual and spatial tasks (learning and extinction). AchE activity in the amygdala was also measured during each process.

Findings / Results:
Results indicated that fear and spatial learning were impaired in SPS animals. SPS animals also had deficits in fear and spatial memory extinction and the effect was significantly higher in female- SPS than in the male-SPS group. In the enzymatic tests, AchE activity was increased during the fear extinction test and incremental changes were more significant in the female-SPS group.

Conclusion and implications:
Collectively, these findings provided evidence that sex differences in response to trauma were at least partly related to less fear extinction potential in female subjects. It also indicated that the extinction deficit was associated with reduced cholinergic activity in the amygdala of female animals.
Development and efficacy of tryptophol-containing emulgel for reducing subcutaneous fungal nodules from Scedosporium apiospermum eumycetoma
Authors: Kitisin Thitinan , Muangkaew Watcharamat , Ampawong Sumate , Sansurin Nichapa , Thitipramote Natthawut , Sukphopetch Passanesh 
Published: October 2022

Background and purpose:
Subcutaneous infections caused by Scedosporium apiospermum present as chronic eumycetomatous manifestations in both immunocompromised and immunocompetent individuals. Serious adverse effects/toxicities from the long-term use of antifungal drugs and antifungal resistance have been reported in patients with S. apiospermum infections. The present study aimed to determine the anti-S. apiospermum activities of fungal quorum sensing molecule known as tryptophol (TOH) and to develop a TOH-containing emulgel for treating S. apiospermum eumycetoma.

Experimental approach:
Anti-S. apiospermum activities of TOH were determined and compared with voriconazole. Effects of TOH on S. apiospermum biofilm formation and human foreskin fibroblast (HFF)-1 cell cytotoxicity were determined. Moreover, TOH-containing emulgel was developed and physical properties, in vitro, and in vivo antifungal activities against S. apiospermum eumycetoma were evaluated.

Findings/Results:
The minimal concentration of TOH at 100 µM exhibited anti-S. apiospermum activities by reducing growth rate, germination rate, and biofilm formation with less cytotoxicity to HFF-1 cells than voriconazole. Further study on the development of an emulgel revealed that TOH-containing emulgel exhibited excellent physical properties including homogeneity, consistency, and stability. Treatment by TOH-containing emulgel significantly reduced subcutaneous mass in a mouse model of S. apiospermum eumycetoma. The histopathological assessment showed marked improvement after 14 days of TOH-containing emulgel treatment.

Conclusion and implications:
TOH could be used as an anti-fungal agent against S. apiospermum infections. A novel and stable TOH-containing emulgel was developed with excellent anti-S. apiospermum activities suggesting the utilization of TOH-containing emulgel as an innovative therapeutic approach in the treatment of S. apiospermum eumycetoma.
VALEURS DE REFERENCE DES PARAMETRES ASSOCIES A LA REPONSE INFLAMMATOIRE CHEZ LES HANDBALLEURS DE L’ELITE AU BENIN / PARAMETER REFERENCE VALUES ASSOCIATED WITH THE INFLAMMATORY RESPONSE IN ELITE HANDBALLERS IN BENIN
Authors: Odjouola Linta Léonce Sèdjro , Dieu Donné Agbodjogbe Kpèdétin Wilfrid , Coffi Quenum Tovignon , Kouassi Jean Paul , Gouthon Gilchrist Fabrice , Nouatin Kocou Basile 
Published: October 2022

<p><strong>Contexte </strong>: Les valeurs de référence des paramètres associés à la réponse inflammatoire des handballeurs d’Afrique subsaharienne et même du monde sont rares. <strong>Objectif</strong> : Cette étude avait pour objectif de proposer les valeurs de référence des paramètres associés à la réponse inflammatoire pour les handballeurs de l’élite du Bénin. <strong>Méthode </strong>: Il s’agit d’une étude prospective, à visée normative, entreprise avec 46 handballeurs masculins, dont 24 seniors (26,4 ± 3,5 ans) et 22 juniors (19,3 ± 0,8 ans). La protéine C-réactive ultrasensible (CRPus), les interleukines Il-6, Il-10 et le tumor necrosis factor (TNF-α) ont été déterminés au début (DPS), puis à la fin de la période de préparation de la saison sportive (FPS). <strong>Résultats</strong> : A la FPS, seul le taux de CRPus s’est accru chez les seniors, de sorte que la différence avec le taux enregistré chez les juniors était significative (p = 0,02). Dans l’échantillon total, la moyenne de l’IL-6 a baissé de 64,1% (p ˂ 0,001), tandis que celle de l’IL-10 s’est accrue de 195,2% (p ˂ 0,001) à la FPS. Les modifications du TNF-α n’ont pas été significatives (p &gt; 0,05). <strong>Conclusion</strong> : Les charges associées aux séances d’entraînement préparatoires à la période de compétition ont modifié les valeurs des paramètres associés à la réponse inflammatoire, enregistrées à la fin de la période de transition. Ces résultats suggèrent de combiner les données des joueurs seniors et juniors collectées à la fin de la période de transition à celles de fin de préparation, de la saison sportive suivantes pour établir les valeurs de référence des paramètres étudiés, à l’usage de l’élite masculine du handball du Bénin.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0965/a.php" alt="Hit counter" /></p>