bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hierarchical Bayesian hedonic regression analysis of Japanese rice wine: is the price right?
Authors: Saito Wakuo , Nakatsuma Teruo 
Published: November 2022

PurposeThis paper aims to formulate a hedonic pricing model for Japanese rice wine, sake, via hierarchical Bayesian modeling estimated using an efficient Markov chain Monte Carlo (MCMC) method. Using the estimated model, the authors examine how producing regions, rice breeds and taste characteristics affect sake prices.Design/methodology/approachThe datasets in the estimation consist of cross-sectional observations of 403 sake brands, which include sake prices, taste indicators, premium categories, rice breeds and regional dummy variables. Data were retrieved from Rakuten, Japan’s largest online shopping site. The authors used the Bayesian estimation of the hedonic pricing model and used an ancillarity–sufficiency interweaving strategy to improve the sampling efficiency of MCMC.FindingsThe estimation results indicate that Japanese consumers value sweeter sake more, and the price of sake reflects the cost of rice preprocessing only for the most-expensive category of sake. No distinctive differences were identified among rice breeds or producing regions in the hedonic pricing model.Originality/valueTo the best of the authors’ knowledge, this study is the first to estimate a hedonic pricing model of sake, despite the rich literature on alcoholic beverages. The findings may contribute new insights into consumer preference and proper pricing for sake breweries and distributors venturing into the e-commerce market.
Case study on barriers to building information modelling implementation in Malaysia
Authors: Munianday Praveena , A. Rahman Rahimi , Esa Muneera 
Published: November 2022

Purpose
There is a dearth of studies conducted by local academics on actual building information modelling (BIM) projects to analyse the actual hurdles of BIM adoption. The majority of BIM research focuses on the technology’s general advantages, disadvantages, issues and limitations. In addition, research on actual BIM projects that have integrated BIM throughout the project is necessary to increase the current low number of BIM users in Malaysia. Consequently, the purpose of this study is to examine the challenges BIM adopters experience while implementing BIM in their projects and how they overcome them.

Design/methodology/approach
An in-depth interview session was used to collect data based on a case-study methodology. In Malaysia, three BIM projects were chosen, given the available resources. To evaluate the data in this qualitative study, NVivo was used.

Findings
According to the findings, the most important elements influencing the adoption of new technology and innovation were people and capital. The most significant impediments to BIM adoption are the appraisal of time and finances, as well as the tolerance of changes in approach.

Originality/value
Collaborative training and BIM education have been the most explored solutions for reducing BIM difficulties. As a result, these concerns and solutions should be investigated and implemented to ensure project success and fully use technological innovation.
A practical framework for ranking universities by their competitive advantages: a mixed methods study on foundation universities in Turkey
Authors: Ayhan İrfan , Özdemir Ali 
Published: November 2022

PurposeThe purpose of this research is to determine the competitive advantages of higher education institutions (HEIs) and create a new methodology to rank universities according to the competitive advantages.Design/methodology/approachThe research determines the competitive advantages of HEIs by analysing expert opinions through a semi-structured interview form, matches codes and themes to performance indicators using Saldana's two-cycle coding methods, evaluates content validity through Lawshe and reveals the item weights of the ranking with analytical hierarchy process (AHP). Simple additive weighting (SAW) and Technique for Order of Preference by Similarity (TOPSIS) methods were used for ranking universities.FindingsSeven dimensions stand out in regard to what should be considered while ranking HEIs: research and publication, education, management, infrastructure, financial resources, human resources and social and economic contribution. Under the 7 dimensions, 69 indicators were determined.Practical implicationsThe research provides a scientific reference point where HEIs can compare themselves with other HEIs regarding where they are in the sector, especially in terms of competitive advantages.Originality/valueAlthough there are many different ranking methods that rank universities in the national and international literature, almost all these methods are largely based on the outputs of the university such as the number of publications, the number of patents, the number of projects, etc. A framework which ranks universities by considering different aspects of the institution, such as management, human resources and financial resources, has not been developed yet. In this respect, this research aims to fill this gap in the literature.
Ocean bottom seismometer data velocity analysis and Kirchhoff pre‐stack time migration
Authors: Qian Hongfei , Wang Xiangchun , Chen Fengying , Yang Zhu , Chen Xuelei , Zhao Linjing 
Published: November 2022

AbstractWith the increasing maturity of ocean bottom seismometer technology in gas hydrate exploration, more and more researchers apply ocean bottom seismometer exploration technology for offshore oil exploration. However, due to the special observation mode of ocean bottom seismometer, it is impracticable to process ocean bottom seismometer data using traditional data processing methods, such as velocity analysis and pre‐stack time migration. This manuscript proposed a new velocity analysis method for ocean bottom seismometer data, which obtains more accurate root‐mean‐square velocity than the existing method. Then we deduced the Kirchhoff pre‐stack time migration formula for ocean bottom seismometer data. Two models demonstrate the correctness of the velocity analysis and migration methods. Finally, the two methods were applied to the actual ocean bottom seismometer data, and the obtained migration profile is consistent well with the profile of towed streamer data in the nearby area.
Gender differences in the laryngectomee experience
Authors: Gresham Malia S. , Mann Hayley , Ward Gregory M. , Payne Michelle A. 
Published: November 2022

AbstractBackgroundLaryngectomy is a pivotal event in patients. lives, with pervasive and far‐reaching effects. Understanding gender differences in these effects may improve care of laryngectomy patients. This paper describes gender differences in the experience after laryngectomy.AimTo explore the similarities and differences in the laryngectomee experience based on gender.Methods & ProceduresFour gender‐matched focus groups were conducted; dialogue was audio recorded, transcribed and studied using interpretative phenomenological analysis (IPA).Outcomes & ResultsA total of 17 laryngectomees, eight female and nine male, age range 41–80 years, participated in focus groups. Laryngectomy represented a turning point in the lives of both genders. Four themes emerged: perception of loss, adjusting to alaryngeal communication, finding a positive outlook and re‐establishing the self. Themes applied to both genders, with subthemes demonstrating similarities and differences between men and women.Conclusions & ImplicationsMen and women experienced destabilization after laryngectomy related to perceived losses and shifts in identity. Men described navigating from physical disability toward recovery of function, while women described an emotional journey concerning loss and rediscovery of meaning in their lives. Understanding the laryngectomee experience in better detail, which includes recognizing gender differences and rejecting a one‐size‐fits‐all approach, may facilitate more effective preoperative counselling and post‐operative support from providers.WHAT THIS PAPER ADDSWhat is already known on the subject
Patients who undergo total laryngectomy often struggle with problems with physical, emotional, and social functioning and decreased quality of life. As the literature currently stands, the understanding of the experience of laryngectomees has primarily focused on the perspective of a singular gender. Thus, this is the first qualitative study specifically investigating differences in the laryngectomee experience between men and women.What this paper adds to existing knowledge
This study finds that women and men both endorse significant mental and physical changes following laryngectomy; however, their perception of their experience differed by gender. Women endorsed alteration to meaningful life and men demonstrated distress related to loss of physical functioning; both genders described laryngectomy as a formative event that helped them rediscover joy and redefine themselves for the better.What are the potential or actual clinical implications of this work?
Our findings suggest men and women have distinct mental and emotional struggles after laryngectomy despite similar physical changes. This suggests that tailoring care with consideration of these gender differences, including preoperative counselling, post‐operative support and gender‐matched visitors or support groups, may help beneficial in recovery after laryngectomy.
Thermal processing implications on microplastics in rainbow trout fillet
Authors: Alak Gonca , Köktürk Mine , Ucar Arzu , Parlak Veysel , Kocaman Esat Mahmut , Atamanalp Muhammed 
Published: November 2022

AbstractHeat treatment is an inevitable step in making meat and meat products ready for human consumption. Researches on ready‐to‐eat foods had shown that foods can also contain microplastics (MPs). The source of the presence of MPs in foods is: air, raw materials, food production stages, or plastics used in packaging. This study was carried out to evaluate the possible effects of the sous‐vide (So‐Vc) technique applied in rainbow trout (Oncorhynchus mykiss) fillets at different temperatures and time intervals on MPs degradation or migration mechanisms and the level of uptake by humans. For this purpose, 7 treatment temperature × 3 various cooking times and So‐Vc technique were applied on rainbow trout fillets. Then, in these fillets, MP presence, size, and shape were researched, as well as polymer types and possible levels of MP uptake by humans were determined. In the analyses, 1.27 ± 0.54 MP/g was found in 1 g of fish tissue. Dimensionally, 67% of MPs was detected as <50 µm and 8% of 500–1000 µm. The dominant shape was determined as a fragment, and the color was black. Six polymer types were determined. The results showed that high temperature (> 65°C) applications promoted polymer degradation. MP migration from packaging material to fillets was not detected. By calculations made on these findings, the lowest intake level by a human was estimated as 6140 MPs units/year. The obtained data provided the initial data to explore and optimize the current understanding of thermally processed products in terms of MPs. This study proved that the sous vide method causes polymer degradation at high temperatures and longer time periods.
Microbiological composition of follicular fluid in patients undergoing IVF and its association with infertility
Authors: Wu Yue‐Rong , Dong Yong‐Hong , Liu Chen‐Jian , Tang Xiao‐Dan , Zhang Ning‐Nan , Shen Jie , Wu Ze , Li Xiao‐Ran , Shao Jing‐Yi 
Published: November 2022

AbstractProblemIn recent years, the incidence of female infertility has risen sharply, which is affected by many factors. It was recognized that female reproductive tract microbes play a role in the process of female conception. If the reproductive tract microbes could solve a certain proportion of infertility, it would certainly reduce the pain and economic burden of many patients. The objective of this study was to investigate the microbial community composition of follicular fluid in infertile patients and its potential impact on infertility.Method of studyFollicular fluid from 49 primary infertility and 52 secondary infertility patients was collected by a negative pressure needle, and the microbiota was analyzed by 16S rDNA sequencing.ResultsIt was found thatLactobacillus, especiallyL. crispatus, might have a positive effect on female pregnancy. Considering the presence or absence of male factors and different body mass indices,L. inersmight inhibit female pregnancy. However,L. inersseemed to play a positive role in egg maturation, whileGardnerellaandCutibacterium acnesmight have a negative effect on female pregnancy.ConclusionsThis study suggested the potential role ofLactobacillusin follicular fluid in improving female infertility and provided a theoretical basis for the future microbiological treatment of female infertility.
Maternal and cord blood BAFF and APRIL levels during pregnancy
Authors: Stohl Hindi E. , Stohl William 
Published: November 2022

AbstractProblemDysregulation of factors vital to the survival B cells and/or plasma cells, such as BAFF and APRIL, could be detrimental to a pregnancy.Method of StudySerially collected first‐, second‐, and third‐trimester serum samples were measured for BAFF and APRIL by ELISA from 150 pregnant women (71 healthy + 79 with a chronic medical disease) at a single medical center. Postpartum serum samples were also collected from the majority of these women. Matched third‐trimester and cord blood samples were collected from 168 women (86 healthy + 82 with a chronic medical disease). Data were analyzed by chi‐square statistic, unpaired t‐test, paired t‐test, Mann‐Whitney rank sum test, Wilcoxon signed rank test, Spearman rank order correlation, and receiver operator characteristic (ROC) curve analyses as appropriate.ResultsMaternal serum BAFF levels declined as the pregnancies progressed and rebounded postpartum, whereas serum APRIL levels remained relatively flat throughout pregnancy and postpartum. Cord BAFF and APRIL levels correlated positively with gestation age and were considerably greater than the corresponding maternal third‐trimester serum BAFF and APRIL levels, respectively. In women who developed preeclampsia, third‐trimester BAFF levels were greater, rather than lower, than their corresponding second‐trimester BAFF levels. ROC curve analysis suggested a potential role for third‐trimester serum BAFF level as a biomarker of preeclampsia.ConclusionsBAFF and APRIL are differentially regulated in the mother during and following pregnancy, whereas each is upregulated in the developing fetus. An increase in third‐trimester serum BAFF level may portend development of preeclampsia.
Glaucoma progression in patients receiving intravitreal anti‐VEGF treatment for neovascular age‐related macular degeneration
Authors: Pirinen Inka , Leinonen Sanna , Helminen Mika , Hujanen Pekko , Vaajanen Anu , Tuulonen Anja , Uusitalo‐Järvinen Hannele 
Published: November 2022

AbstractPurposeThe purpose of this study was to investigate how often glaucoma and neovascular age‐related macular degeneration (nAMD) occur in the same patient and to evaluate whether glaucoma progression is faster in eyes treated with intravitreal anti‐VEGF medications for nAMD.MethodsThis single‐centre retrospective real‐world data (RWD) consists of medical records of 6314 glaucoma and 2166 nAMD patients treated in 2008–2017 in Tays Eye Centre, Finland. To study glaucoma progression, changes in visual fields (mean deviation [MD], dB/year), IOP (mmHg/year) and fundus photographs (progression, yes/no) were compared in glaucoma eyes with and without anti‐VEGF treatment for nAMD and ≥1 year follow‐up.ResultsDuring the 10‐year period, 147 patients with glaucoma received intravitreal anti‐VEGF treatment for nAMD corresponding to 2% of glaucoma and 7% of nAMD patients. The mean change in MD was −0.70 dB/year (SD 1.8) vs. −0.27 dB/year (SD 1.7) (p = 0.027) in glaucoma eyes with (n = 37) and without (n = 4304) anti‐VEGF injections, respectively. In patients with bilateral glaucoma and unilateral nAMD treated with anti‐VEGF injections (n = 20), MD declined at −0.62 dB/year (SD 1.9) vs 0.33 dB/year (SD 1.5) (p = 0.654), and glaucoma progression was detected in 14/20 vs 10/20 (p = 0.219) fundus photographs in eyes with anti‐VEGF treatment compared with their untreated fellow eyes.ConclusionnAMD and glaucoma were found co‐existing in the same eye at rates that were similar to the age‐corrected prevalence of the two diseases in the general population. Our results suggest that intravitreal anti‐VEGF treatment for nAMD may accelerate glaucoma progression.
The Liverpool alcohol‐related liver disease algorithm identifies twice as many emergency admissions compared to standard methods when applied to Hospital Episode Statistics for England
Authors: Dhanda Ashwin , Bodger Keith , Hood Steve , Henn Clive , Allison Michael , Amasiatu Chioma , Burton Robyn , Cramp Matthew , Forrest Ewan , Khetani Meetal , MacGilchrist Alastair , Masson Steven , Parker Richard , Sheron Nick , Simpson Ken , Vergis Nikhil , White Martin ,   BASL ARLD SIG National Service Evaluation Group
Published: November 2022

SummaryBackgroundEmergency admissions in England for alcohol‐related liver disease (ArLD) have increased steadily for decades. Statistics based on administrative data typically focus on the ArLD‐specific code as the primary diagnosis and are therefore at risk of excluding ArLD admissions defined by other coding combinations.AimTo deploy the Liverpool ArLD Algorithm (LAA), which accounts for alternative coding patterns (e.g., ArLD secondary diagnosis with alcohol/liver‐related primary diagnosis), to national and local datasets in the context of studying trends in ArLD admissions before and during the COVID‐19 pandemic.MethodsWe applied the standard approach and LAA to Hospital Episode Statistics for England (2013–21). The algorithm was also deployed at 28 hospitals to discharge coding for emergency admissions during a common 7‐day period in 2019 and 2020, in which eligible patient records were reviewed manually to verify the diagnosis and extract data.ResultsNationally, LAA identified approximately 100% more monthly emergency admissions from 2013 to 2021 than the standard method. The annual number of ArLD‐specific admissions increased by 30.4%. Of 39,667 admissions in 2020/21, only 19,949 were identified with standard approach, an estimated admission cost of £70 million in under‐recorded cases. Within 28 local hospital datasets, 233 admissions were identified using the standard approach and a further 250 locally verified cases using the LAA (107% uplift). There was an 18% absolute increase in ArLD admissions in the seven‐day evaluation period in 2020 versus 2019. There were no differences in disease severity or mortality, or in the proportion of admissions with decompensation of cirrhosis or alcoholic hepatitis.ConclusionsThe LAA can be applied successfully to local and national datasets. It consistently identifies approximately 100% more cases than the standard coding approach. The algorithm has revealed the true extent of ArLD admissions. The pandemic has compounded a long‐term rise in ArLD admissions and mortality.
No adverse effects on periarticular tissue by intra‐articular vitamin D analogue calcipotriol in a reduced‐dose zymosan‐induced arthritis model in rats
Authors: Huovinen Jere , Lohela Jesse , Kauppinen Sami , Finnilä Mikko , Laaksonen Sakari , Voipio Hanna‐Marja , Huhtakangas Johanna A. , Lehenkari Petri 
Published: November 2022

AbstractCalcipotriol, a vitamin D analogue, is an antiproliferative and anti‐inflammatory drug currently used in psoriasis. Here, our aim was to analyse the safety of calcipotriol for cartilage and bone in alleviated‐dose (0.1 mg instead of usual ≥1mg dose) zymosan‐induced arthritis in rats. Theoretically, high doses of vitamin D or analogues could have detrimental effects on bone or cartilage. The rats were divided into four groups: vehicle (n = 9), dexamethasone 0.1 mg/kg (n = 9), calcipotriol 0.1 mg/kg (n = 8) and negative control (n = 10) with no injections. Arthritic rats were given phosphate‐buffered saline (PBS) injections to left knees as a control. After euthanasia on day 8, all knees were imaged with micro‐computed tomography for surface lesions and decalcified for histological analyses. Contrary to our expectations, no significant changes could be observed in the tomography data and histological scores among the three treatment groups or between the vehicle‐treated and non‐arthritic group. Calcipotriol did not cause adverse effects on cartilage or subchondral bone within a week, suggesting that it could be safely used in local treatment of arthritis. The alleviated model caused synovitis with local and systemic inflammatory response without cartilage erosions, which might be useful in studying self‐limiting synovitis where cartilage or bone effects are not of primary interest.
Tocilizumab for the treatment of chronic antibody mediated rejection in kidney transplant recipients
Authors: Khairallah Pascale , Robbins‐Juarez Shelief , Patel Shefali , Shah Vaqar , Toma Katherine , Fernandez Hilda , Dube Geoffrey K. , King Kristen , Mohan Sumit , Husain Syed Ali , Morris Heather , Crew Russell John 
Published: November 2022

AbstractBackgroundChronic active antibody‐mediated rejection (CAAMR) constitutes a dominant form of late allograft failure. Several treatment strategies directed at CAAMR have been attempted but proven ineffective at delaying kidney function decline or reducing donor‐specific antibodies (DSA). We describe our single‐center experience using tocilizumab in patients with CAAMR.MethodsThis is a retrospective analysis using electronic medical records. 38 kidney transplant recipients at Columbia University Irving Medical Center who had been prescribed tocilizumab and followed for at least 3 months between August 2013 through December 2019 were included.ResultsTocilizumab use was associated with a decrease in the rate of estimated glomerular filtration rate (eGFR) decline in the 6 months following treatment initiation as compared to the 3 months before tocilizumab was initiated (difference between slopes before and after initiation of treatment = 2.6 mL/min/1.73 m2 (SE = .8, p = .002) per month for up to 6 months following Tocilizumab initiation). Allograft biopsies showed significant improvement in interstitial inflammation scores (score 1(0,1) to 0 (0,1), p = .03) while other histologic scores remained stable. There was no significant change in proteinuria or DSA titers post‐treatment with tocilizumab.ConclusionsTreatment of CAAMR with tocilizumab was associated with a decrease in the rate of eGFR decline and a reduction in interstitial inflammation scores in patients with CAAMR.