bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effector selection precedes movement specification: evidence from repetition effects in motor planning
Authors: Seegelke Christian , Heed Tobias 
Published: February 2025

Abstract
Motor performance is influenced by movements that were performed shortly prior. For example, reaction times (RTs) for successive movements are reduced when executed with the same effector, even if the specifics of the consecutive movements differ. These findings have been taken to support the notion that repetition effects in motor planning reflect the involvement of effector-specific motor plans. However, previous studies have confounded motor and visual aspects of repetition: movements have typically been instructed via visual cues, and movement repetition, therefore, implied repeating also the visual cue, so that the latter may be (at least partly) responsible for the observed RT effects. In the present study, participants performed two movements in succession, a prime and a probe action, either with their left or right hand and in one of two directions, inward or outward relative to the body midline. We used different cues for prime and probe actions, so that movement repetitions did not involve repetition of the visual cue. Participants initiated successive same-limb movements faster than different-limb movements, but this RT advantage was smaller than observed in previous work. Moreover, repeating movement direction also led to a decrease in RT, though only in combination with hand repetition. Whereas these findings imply that visual cue repetition can contribute to accelerated RTs in movement repetition, they confirm that the recent motor history affects motor planning. Furthermore, they support the idea of a hierarchical framework of motor planning in which effector selection precedes specification of motor parameters.
Yeasts Prefer Daycares and Molds Prefer Private Homes
Authors: Kauserud Håvard , Martin-Sanchez Pedro M. , Estensmo Eva Lena , Botnen Synnøve , Morgado Luis , Maurice Sundy , Høiland Klaus , Skrede Inger 
Published: February 2025

Abstract
Worldwide, people spend most of their time indoors; in their homes, workplaces, schools, and daycares. Indoor fungi can cause negative health effects due to the production of toxins or volatiles that trigger the immune system of the occupants. To what degree indoor fungi (mycobiomes) differ between buildings with different usage is poorly known. Here, we compare the indoor mycobiomes in 123 children’s daycare centers and 214 private homes throughout Norway, as revealed by metabarcoding of DNA extracted from dust samples collected by community scientists. Although the fungal richness per se was similar in dust samples from daycares and homes, the fungal community composition differed. Yeast fungi, distributed mainly across the orders Saccharomycetales, Filobasidiales, and Tremellales, were proportionally more abundant in the daycares, while filamentous fungi, including spore-producing molds such as Aspergillus, Penicillum, and Cladosporium, were relatively more abundant in homes. Number of occupants, which is considerably higher in daycares, correlated significantly with the fungal community shift. We hypothesize that the density of occupants and their age distribution drive the systematic difference of yeasts and filamentous fungi in the two building types.
Enzymes that catalyze cyclization of β-1,2-glucans
Authors: Nakajima Masahiro , Motouchi Sei , Tanaka Nobukiyo , Masaike Tomoko 
Published: February 2025

Abstract
β-1,2-Glucans are physiologically important polymers for interactions such as symbiosis and pathogenesis between organisms and adaptation to environmental changes. However, rarity of β-1,2-glucans in nature limits exploration of related enzymes. Recently, many β-1,2-glucan-degrading enzymes have been found after identification of a novel phosphorylase acting on β-1,2-glucooligosaccharides. The expansion of the repertoire has reached revelation of the cyclization mechanism of cyclic β-1,2-glucan synthase and led to finding of new enzymes catalyzing cyclization of β-1,2-glucans in a manner different from cyclic β-1,2-glucan synthase. In this review, we mainly focus on newly found enzymes that catalyze cyclization of β-1,2-glucans along with existence of β-1,2-glucan-associated carbohydrates in nature and introduction of the repertoire of β-1,2-glucan-degrading enzymes.

Key points
• Newly found domain which cyclizes β-1,2-glucan created a new glycoside hydrolase family.

• Cyclization is performed with a unique mechanism.

• α-1,6-Cyclized β-1,2-glucan is produced by an enzyme in another newly found family.
The role of nerve transfers in chronic nerve compression syndromes
Authors: Kennedy Patrick J. , Nag Shayoni , Otto-Moudry Reade , Moore Amy M. 
Published: February 2025

Abstract

Purpose
Compression neuropathy is a common problem that results in impaired axonal conduction, and with time, numbness, tingling and weakness from muscle atrophy. Supercharge reverse end-to-side (SETS) nerve transfers have emerged as a novel approach to augment function in chronic nerve compression syndromes with minimal donor site morbidity. This review answers the question, “What are the indications, surgical techniques, and nuances of SETS nerve transfers for ulnar, axillary, radial, and femoral compression neuropathies?”.

Methods
This article reviews current literature and technical components of the use of SETS in chronic nerve compression syndromes.

Results
SETS nerve transfers improve functional outcomes and reduce disability in chronic nerve compression syndromes with limited donor site morbidity. SETS nerve transfers for ulnar, axillary, and femoral compressive neuropathy improve muscle strength, as demonstrated by increased MRC scores. It has also been shown that SETS transfers decrease clawing in ulnar nerve compression and pain in axillary nerve compression. More research is needed for SETS transfers for radial nerve compression neuropathies.

Conclusion
SETs nerve transfers have emerged as a novel approach to restore function and reduce pain and dysfunction in chronic nerve compression syndromes. SETS nerve transfers have minimal donor site morbidity and improve the strength and function of muscles innervated by the effected “recipient” nerve. This review explores the indications and surgical techniques of SETS nerve transfers for ulnar, axillary, radial, and femoral compression neuropathies as well as their reported outcomes.
Management Strategies for Dissolved Organic Carbon Reduction from Forested Watersheds using the SWAT-C model
Authors: Lee Dongjun , Karki Ritesh , Kalin Latif , Isik Sabahattin , Srivastava Puneet , Zhang Xuesong 
Published: February 2025

Abstract
Forests serve as crucial carbon sinks, yet quantifying carbon cycle processes within forested watersheds is challenging due to inherent complexities, including multiple carbon pools and variability. Dissolved organic carbon (DOC) transport from forests significantly impacts drinking water quality since it interacts with chlorine to form disinfection byproducts. Although the Soil and Water Assessment Tool-Carbon (SWAT-C) has been widely used to understand carbon fluxes at the watershed scale, the model has been primarily evaluated in non-forested watersheds and loading to aquatic systems, often overlooking terrestrial carbon fluxes from forested regions within watersheds of interests. This study assessed the applicability of SWAT-C in simulating carbon fluxes in both terrestrial and aquatic systems in the forested Big Creek watershed located in the south-central United States (U.S.), which also serves as a drinking water source, and analyzed dominant pathways of DOC transport across the landscape. Additionally, three management scenarios (i.e., forest conversion, raking in forests, and adjusting biomass harvest in croplands) aimed at reducing DOC transport were evaluated. Calibration efforts using remotely sensed as well as datasets demonstrated the proficiency of SWAT-C in simulating both terrestrial and aquatic carbon fluxes in forest-dominated regions. Results emphasize the importance of initializing and calibrating the parameters of dominant land use/cover types to enhance model performance in simulating carbon fluxes. The study found that all evaluated management scenarios can reduce DOC transport into streams, with the conversion of the dominant loblolly pine forests to restored longleaf pine forests achieving a 40% reduction in forest-derived DOC yields. These findings offer valuable insights for watershed-scale carbon cycling modeling and inform management strategies in forest-dominant watersheds to mitigate DOC yields.
Genomes of the Bacterial Endosymbionts of Carrot Psyllid Trioza apicalis Suggest Complementary Biosynthetic Capabilities
Authors: Thompson Sarah , Wang Jinhui , Schott Thomas , Nissinen Riitta , Haapalainen Minna 
Published: February 2025

Abstract
Carrot psyllid Trioza apicalis is a serious pest of cultivated carrot and also a vector of the plant pathogen ‘Candidatus Liberibacter solanacearum’ (Lso). To find out whether T. apicalis harbours other species of bacteria that might affect the Lso infection rate, the bacterial communities and metagenome in T. apicalis were studied. Lso haplotype C was detected in a third of the psyllids sampled, at different relative amounts. Surprisingly, T. apicalis was found to harbour only one secondary endosymbiont, a previously unknown species of gamma proteobacterium endosymbiont (Gpe), beside the primary endosymbiont ‘Candidatus Carsonella ruddii’ (CCr). The relative abundancies of these two endosymbionts were approximately equal. The genomes of CCr, Gpe and Lso were assembled from a T. apicalis metagenome sample. Based on the 16S rRNA gene, the closest relative of Gpe of T. apicalis could be a secondary endosymbiont of Trioza magnoliae. The 253.171 kb Gpe genome contains all the tRNA and rRNA genes and most of the protein-coding genes required for DNA replication, transcription and translation, but it lacks most of the genes for amino acid biosynthesis. Gpe has no genes encoding cell wall peptidoglycan synthesis, suggesting it has no cell wall, and could thus live as an intracellular endosymbiont. Like the CCr of other psyllids, CCr of T. apicalis retains a broad amino acid biosynthetic capacity, whilst lacking many genes required for DNA replication and repair and for transcription and translation. These findings suggest that these two endosymbionts of T. apicalis are complementary in their biosynthetic capabilities.
Exploring the Complete Chloroplast Genomes of Key Lamiaceae Species Uncovers the Secrets of Evolutionary Dynamics and Phylogenetic Relationships
Authors: Alp Furan Mehmet , Yildiz Faruk , Kaya Ozkan 
Published: February 2025

Abstract
Chloroplast genome analysis provides crucial insights into plant evolution, classification, and conservation strategies. This study aimed to conduct a comprehensive comparative analysis of chloroplast genome architecture, gene content, and evolutionary relationships among five species of Lamiaceae (Lavandula angustifolia, Mentha × piperita, Ocimum × africanum, Salvia japonica, and Thymus serpyllum). Complete chloroplast genome sequences were retrieved from the NCBI database and analyzed using a systematic bioinformatics pipeline. Genome annotation was performed using Geneious Prime software, while repetitive sequence analysis was conducted using Tandem Repeats Finder. Phylogenetic relationships were reconstructed using MEGA software, implementing both the DualBrothers model and Neighbor-Joining method. The analyzed genomes exhibited the characteristic quadripartite structure, with sizes ranging from 152,048 to 153,995 base pairs and GC content between 37.8 and 38.0%. Each genome contained 131–134 genes, including 50 protein-coding sequences, 8 rRNA genes, and 37 tRNA genes. Comparative analysis revealed region-specific GC content variations, with IR regions showing the highest (43.0–43.4%), followed by LSC (35.9–36.2%) and SSC regions (31.6–32.1%). Codon usage analysis demonstrated a significant bias toward T/C-ending codons, particularly TTT, AAA, and AAT, correlating with the high AT content. Notable variations were observed at the LSC/IR/SSC junction regions, attributed to IR expansion and contraction. Molecular clock analyses indicated consistent evolutionary rates across the studied species. These findings provide valuable insights into the molecular evolution of Lamiaceae chloroplast genomes and establish a foundation for future research in plant molecular biology, systematic studies, and conservation efforts.
The advanced lung cancer inflammation index as a useful prognostic indicator for patients who underwent radical nephroureterectomy for upper tract urothelial carcinoma
Authors: Hatayama Tomoya , Goto Keisuke , Kohada Yuki , Nishida Kensuke , Ueno Takeshi , Furutani Tomoki , Hashimoto Kunihiro , Takemoto Kenshiro , Naito Miki , Miyamoto Shunsuke , Kobatake Kohei , Sekino Yohei , Kitano Hiroyuki , Goriki Akihiro , Hieda Keisuke , Hinata Nobuyuki 
Published: February 2025

Abstract

Purpose
We aimed to evaluate the ability of the advanced lung cancer inflammation index (ALI) to predict the prognosis of patients who underwent radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). We also aimed to compare the ALI with other inflammatory or nutritional indices as prognostic indicators.

Methods
We retrospectively evaluated patients who underwent RNU for UTUC at multiple centers between January 2010 and April 2024. We calculated the ALI before RNU and divided the patients into the low ALI and high ALI groups. We used 1:1 propensity score matching (PSM) to adjust the clinicopathological differences between two groups. We compared the overall survival (OS) and recurrence-free survival (RFS) of the low and high ALI groups using the Kaplan-Meier method. Furthermore, we assessed the ALI as a predictor of OS and RFS using a multivariate Cox proportional hazards regression analysis.

Results
Of 488 patients (48.3% low ALI group), 160 patients from each group were matched. The Kaplan-Meier analysis revealed that the OS (p = 0.009) and RFS (p = 0.006) of the low ALI group were significantly shorter than those of the high ALI group. According to a multivariate analysis that included clinicopathological prognostic indicators, a low ALI was an independent predictor of poor OS (p = 0.014) and RFS (p = 0.038). Furthermore, according to the multivariate analysis including other inflammatory or nutritional indices, the ALI was an independent predictor of poor OS (p = 0.024) and RFS (p = 0.044).

Conclusions
The ALI was a significantly useful prognostic predictors of patients with UTUC who underwent RNU.
The differences between the subtypes of obstructive sleep apnea among different provinces in Turkey: a multicenter study
Authors: Yalim Sidika Deniz , Bayram Nazan , Ozdemir Imran , Cingi Cemal , Muluk Nuray Bayar 
Published: February 2025

Abstract

Purpose
Our aim in this study is to investigate the significance and implications of different clinical subtypes of patients with obstructive sleep apnea syndrome (OSAS) in three different sleep centers from varied provinces.

Methods
Between January 2023 and November 2024, 330 patients from three sleep centers (Adana, Gaziantep, and Istanbul) were retrospectively examined for age, gender, body mass index (BMI), polysomnography parameters, sleep stages, arousals, oxygen parameters, heart rates, apnea-hypopnea indexes (AHI) and snoring.

Results
OSAS patients of Gaziantep were fat and severe OSAS patients who slept lightly but efficiently at lower oxygen levels with longer durations. They fell into Rapid Eye Movement (REM) sleep quickly. The number of hypopneas is high. OSAS patients of Adana sleep deeply, frequently wake after sleep onset, and snore less. The number of obstructive apnea is high. OSAS patients of Istanbul sleep efficiently but snore a lot. REM oxygen saturation, oxygen desaturation index (ODI) levels, and the average heart rate were high in Istanbul. The number of central and mixed apneas is high.

Conclusions
Sleep patterns and oxygen measurements varied among clinical subtypes of patients with OSAS, as well as among provinces. Understanding regional or subtype-specific OSAS could alter practice because treatment can be planned according to the severity of OSAS.
Lust im Lockdown – Das Sexuelle unter dem Brennglas der Coronapandemie
Authors: Busch Charlotte , Quindeau Ilka , Herzog Dagmar , Lemke Richard , Herrmann Friederike , Tannich Pascal , Schweizer Katinka 
Published: February 2025

Zusammenfassung
Die Coronapandemie dient dieser Forschungsarbeit als vergrößerndes Brennglas zur Analyse gesellschaftlicher und individueller Konflikte um das Sexuelle. Es wird untersucht, welchen Umgang die Subjekte während der Coronapandemie mit ihrer Sexualität gefunden haben, und welche gesellschaftliche Vermittlung und welcher soziale Austausch diesbezüglich stattfanden. Durch die Krisenhaftigkeit der Coronapandemie wird ein verschärftes (triebinduziertes) Dilemma zwischen Befriedigung und Verzicht angenommen; dieses aktualisierte unbewusste Konflikte und Wünsche und rief Abwehrformationen auf den Plan, die anhand sexueller Szenen und Skripte untersucht werden. Methodisch werden dafür ein Videobeitrag aus den öffentlich-rechtlichen Medien über Dating und Sexualität im Lockdown mit der tiefenhermeneutischen Methode des szenischen Verstehens analysiert sowie die dazugehörigen Nutzer:innenkommentare mittels der Codiersoftware MAXQDA qualitativ-inhaltsanalytisch ausgewertet. Die Ergebnisse zeigen, dass das Sexuelle in der Pandemie nicht in dessen Ambivalenz ausgehalten werden konnte und überwunden geglaubte sexuelle Skripte über Geschlecht und Sexualität hervorbrachte, was mittels Schiefheilungen reguliert werden sollte. Auf diese Weise konnten verpönte Wünsche und Ängste um das Sexuelle zunächst in Schach gehalten werden, was langfristig selbst Leid und Frust erzeugen kann.
Laparoscopic inguinal hernia repair with self-fixated meshes: a randomized controlled trial
Authors: Thölix Anna-Maria , Kössi Jyrki , Grönroos-Korhonen Marie , Harju Jukka 
Published: February 2025

Abstract

Background
Laparoscopic inguinal hernia surgery leads to rapid recovery and low complication rates. An alternative to fixate the mesh is using a self-fixated mesh.

Methods
From April 2021 to June 2024, we conducted a randomized controlled trial comparing self-adhesive mesh (Adhesix™) with self-gripping mesh (Progrip™) in laparoscopic inguinal hernia surgery (TAPP and TEP). Adult patients scheduled for day surgery were included in the study with a 1-year follow up. The primary endpoint was the number of analgesics (Paracetamol or Ibuprofen) used during the first post-operative week. Secondary outcomes were pain-related issues, complications, and recurrence rate.

Results
A total of 174 patients participated; 90 received Adhesix™ (group A) and 84 Progrip™ (Group P). Forty-six (26.4%) patients had recurrent hernia, 68 (39.1%) had unilateral and 60 (34.5%) had bilateral primary hernias. A total of 156 (90%) patients completed follow up. The number of analgesics during the first post-operative week was comparable between groups (P 22.9, A 21.2 tablets, p = 0.461). Group P used more analgesics during day 1, after which no difference was observed. In general, all participants used analgesics after surgery regularly for 10.8 days (SD 10.6) and occasionally for 15.9 days (SD 16.9). Time to return to work and normal activities was 16.1 days (SD 10.8) and 16.6 days (SD 9.6), respectively. More patients in group P reported moderate or severe pain (numeric rating scale > 3) during exercise 3 months after surgery (P 15.4%, A 3.1%, p = 0.035), although no difference was observed at 1 year after surgery. Both groups had significantly improved quality of life measures in physical aspects of the RAND-36 Item Health Survey after 3 months. Two recurrences, one in each group (1.1%) occurred.

Conclusion
The use of Adhesix was non-inferior to Progrip in laparoscopic surgery. Surgery using either mesh led to rapid recovery and improved quality of life.
This trial was registered in ClinicalTrials.gov (NCT05091853).

Graphical abstract
Urinary oxygen tension measurement using a 3-way silicone urinary catheter with enhanced capability for urine collection
Authors: Kato Takao , Kobashi Riku , Watanabe Fumikazu , Koyama Kaoru 
Published: February 2025

Abstract
Acute kidney injury (AKI), particularly during cardiac surgery, severely affects patient outcomes, yet current diagnostics using serum creatinine levels delay detection. This study investigates real-time urinary oxygen tension (PuO2) as an alternative early marker and correlates it with renal medullary oxygen tension for potential AKI prediction. We developed a modified 3-way silicone urinary catheter designed for more reliable urine collection and evaluated its performance in terms of PuO2 measurement accuracy. The results of the experiment showed that the improved catheter enabled continuous urine collection, but it was suggested that the oxygen permeability of the silicone material may have caused an increase in PuO2 level. These results suggest that material selection, particularly oxygen permeability, has a significant impact on PuO2 measurements and highlight the need for alternative low-permeability materials to improve the reliability of PuO2-based AKI diagnostics.
Static analysis to make the most of CHERI C/C++ for existing code: improving memory safety at scale
Authors: Dudina Irina , Stark Ian 
Published: February 2025

Abstract
We describe and evaluate custom static analyses to support transitioning existing C/C++ codebases to CHERI hardware. CHERI is a novel architectural extension, implemented for RISC-V and AArch64, that uses capabilities to provide fine-grained memory protection and scalable software compartmentalization. While the existing CHERI toolchain can recompile large code collections for the platform with only a few source changes, those changes are nonetheless critical: we demonstrate that static analysis can help to identify where they are needed and what must be done to avoid later runtime faults. We provide custom checkers for the Clang Static Analyzer to handle capability alignment, copying through memory, and manipulation as integers. Beyond simply picking up problems in existing code, we also have checkers that identify where code can take advantage of capabilities to better enforce least privilege and improve spatial memory safety. We evaluate all implemented checkers on a sample of packages from the CheriBSD ports library (408 packages, "Equation missing" analyzed) and confirm by analyzing true-positive warning rates that the reports produced are sufficiently high quality for practical use.
Deep crowd anomaly detection: state-of-the-art, challenges, and future research directions
Authors: Sharif Md. Haidar , Jiao Lei , Omlin Christian W. 
Published: February 2025

Abstract
Crowd anomaly detection is one of the most popular topics in computer vision in the context of smart cities. A plethora of deep learning methods have been proposed that generally outperform other machine learning solutions. Our review primarily discusses algorithms that were published in mainstream conferences and journals between 2020 and 2022. We present datasets that are typically used for benchmarking, produce a taxonomy of the developed algorithms, and discuss and compare their performances. Our main findings are that the heterogeneities of pre-trained convolutional models have a negligible impact on crowd video anomaly detection performance. We conclude our discussion with fruitful directions for future research.