bluuebunny/crossref_metadata_2025_split huggingface dataset:
Competency-Based Assessment in Entrepreneurship Education in Kenya’s Tertiary Institutions
Authors: Moindi Rose , Nyatuka Benard 
Published: July 2022

Education systems worldwide are shifting to knowledge-based curricula with emphasis on the learners’ acquisition of relevant competencies. Entrepreneurship education was introduced in tertiary institutions in Kenya in 1999 to produce entrepreneurs, including preparing graduates for the world of work. However, limited studies have focused on the assessment of acquisition of such competencies, especially in entrepreneurship education. This study was designed to examine the effectiveness of assessment modes used in entrepreneurship education in imparting requisite competencies among students in tertiary institutions in the country. The study adopted a cross-sectional research design. A total of 412 students selected from three tertiary institutions were involved in the study. Data were collected using questionnaires and analysed quantitatively using descriptive and inferential statistics. The study showed that written examinations were the most commonly used mode of assessment of entrepreneurship education, followed by projects and attachment. The study revealed that there is no significant difference in the influence of the mode of assessment as adopted in the different tertiary institutions in fostering the acquisition of competencies (F Ratio<F Critical) (0.835<3.02). However, when the requisite competencies were compared, the study showed that the mode of assessment adopted enhanced acquisition of ideas and opportunities (0.313 units) and resources (0.364 units) competencies more compared to the into-action competencies (0.249 units). To enhance the acquisition of relevant competencies, the study recommends adoption of different appropriate modes of assessment in entrepreneurship education.
Technology Focus: Cementing and Zonal Isolation (May 2022)
Authors: James Simon 
Published: July 2022

Over the past year, the number of cementing and zonal-isolation papers was much lower than usual because of the cancellation and postponement of several conferences. The overall impact, however, was mitigated by the transformation of several conferences to online events. I attended one virtual event and was pleasantly surprised with the value of the technical discussions that immediately followed each paper presentation and the willingness of authors to follow up on discussions after the conference.
The development of new technology can take a significant amount of time and resources, and full worldwide introduction may take many years, giving rise to a commercial risk for the technology developer. One paper published last year described the first case history of self-healing cement technology in one geographical area more than 10 years after the publication of the first field application of the technology.
In the October 2021 issue of JPT, SPE President Kamel Ben-Naceur discussed the importance of collaboration in solving technical problems quickly and efficiently. Three of the papers selected in this section are from collaborations between multiple companies pooling their expertise and resources to develop solutions for complex problems that could not be addressed efficiently by individual companies. Papers SPE 204015 and SPE 208782 issue from consortia whose goals are to improve the efficiency and reliability of plugging-and-abandonment operations. Paper SPE 204103 is a jointly funded collaboration evaluating CO2-resistant cement with a new experimental methodology to accelerate chemical interactions between the cement and CO2, thus shortening the validation time.
The commercial risks associated with the incremental developments of existing technology can be acceptable more readily to individual companies, although this does not mean that efficient internal teamwork is not required. The three other papers selected are all supported and authored by individual companies, but each is a collaboration between multiple people with different expertise—experimental and poromechanical modeling expertise in paper
SPE 206144, chemical synthesis and microfluidics expertise in paper SPE 207472, and cement chemistry and experimental expertise in paper SPE 208679.
Recommended additional reading at OnePetro: www.onepetro.org.
SPE 204103 Evaluation of New Innovative Cement Blend for Enhanced CO2 and H2S Resistance by Gunnar Lende, Halliburton, et al.
SPE 206144 Advanced Cement Mechanical Integrity for Thermal Wells by Manh-Huyen Vu, Curistec, et al.
SPE 207472 Associative Microgels, New Self-Adaptive Systems To Control Fluid Loss in Well Cementing by Arnaud Cadix, Solvay, et al.
Metaverse skiing system linked with real-time environmental elements of the ski resort
Authors: Li Tan , Wang Hong , Yue Zaituo , Lan Qin , Fan Dongchuan , Li Ziyang , Zhang Bo , Yan Shiyu 
Published: July 2022

Abstract
This paper presents a virtual ski training system based on changes in environmental elements of ski resort. The aim of the system is to allow skiers to ski training without going to a ski resort, increase tactical training in the face of different environments and help skiers improve their performance. The system uses VR technology to construct a realistic ski training scenario. 5G cloud platform transmissions are connected to the actual ski resorts to obtain real-time environmental elements data to import into the VR system in order to construct a dynamic model of the environment. The effectiveness of the system was verified through a combination of indoor and outdoor tests to analyse participants' skiing speed in both real and virtual scenarios. In conjunction with questionnaires completed by the participants, differences in the effectiveness of the participants' experience of the different dimensions of the system were analysed. The results show that this VR system is effective in simulating actual ski resorts and is an effective aid for skiers, especially less experienced ski students.
Locked posterior Shoulder Dislocation with impression Fracture treated all arthroscopically with the use of an Allograft Bone Block A Case Report
Authors: Blasiak Adrian , Podsiadlo Mikolaj , Śliwa Marek , Brzoska Roman 
Published: July 2022

Abstract
Locked posterior shoulder dislocations are uncommon and poses many difficulties in diagnosis. They are often overlooked during initial exam- ination and delayed diagnosis adversely affects healing process. Apart from many open treatment options there are reports of single attempts to treat such cases arthroscopically. We present an original case of a posterior locked dislocation of the shoulder joint with a fracture of the lesser tuberosity followed by reverse Hill-Sachs fracture, treated in a novel fashion all-arthroscopically with the use of allogenic bone graft. According to Constant Shoulder Score that tries to asses functional and subjective performance of the shoulder joint before the operation and after 12 months, we achieved a leap from 11% to 84%. The patient restored almost full range of motion and painless movement in activ- ities of daily life as well as during sports. The use of an arthroscope reduces the invasiveness of the procedure, improves visualization of the joint and allows augmentation of the bone loss without perform- ing an open approach. We believe that this is A promising method of treatment for selected cases of locked posterior shoulder dislocation.
High-sensitivity C-reactive Protein is a Predictor of Depression in Patients with Mild Traumatic Brain Injury
Authors: Eujene Jung , Ryu Hyun Ho 
Published: July 2022

Abstract
IntroductionDepression is one of the most common psychological problems after mild traumatic brain injury (mTBI) and affects various aspects of life quality. Previous studies demonstrated that systematic inflammation might lead to unfavorable outcomes, including depression after TBI. Therefore, we analyzed the relationship between the serum level of high sensitive C-reactive protein (hsCRP), a sensitive biomarker of systematic inflammation, and depression incidence after mTBI.MethodsWe used data from Korea’s Level-1 trauma center registry between Jan 2018 to Dec 2019. The population of our study was adult mTBI patients who visited the Level-1 trauma center using emergency medical service (EMS). We used the serum level of hsCRP measured just after arrival at the emergency department as the primary data input. The main outcome was depression evaluated 6 months after hospital discharge using the Beck depression inventory. Multivariable logistic regression analyses were performed to estimate the effect of hsCRP level on depression incidence. In addition, interaction analyses of the association between hsCRP and fever on depression incidence were performed.ResultsA total of 257 mTBI patients were enrolled. The multivariable logistic regression analysis showed that an elevated serum level of hsCRP was associated with higher odds of depression (aOR (95% CI): 1.34 (1.03—1.69)). The association was maintained only in the fever group (1.42 (1.14—1.78)).ConclusionsElevated serum level of hsCRP was associated with an increased incidence of depression 6 months after hospital discharge. This effect was maintained in the presence of fever. Our study results suggest the need for adopting strategies to prevent depression when systematic inflammation is indicated by CRP elevation and/or fever in mTBI patients.
Gender Differences in Obstructive Sleep Apnea with Comorbid Treatment-Resistant Depression
Authors: Kasurak Emily , Hawken Emily , Kolar Dusan , Jokic Ruzica 
Published: July 2022

Abstract
Background. A bidirectional relationship between major depression and obstructive sleep apnea has been established, suggesting the possibility of overlapping and compounding disease processes. Depression, however, while more prevalent in women, is a highly heterogeneous disorder and can be difficult to treat regardless of gender. A common overlapping symptom of depression and obstructive sleep apnea is fatigue. Gender differences in obstructive sleep apnea symptomatology (and fatigue in particular) are also consistently observed. Here, we investigate obstructive sleep apnea in specific relation to treatment-resistant depression. Methods. A cross-sectional design was used to analyse data from 94 patients with treatment-resistant depression from a subspecialist mood disorders outpatient service who had no previous sleep assessment. Participants completed overnight polysomnography and a battery of rating scales assessing mood, sleep, and daytime functioning. Linear regression models determined whether presence of fatigue in treatment-resistant depression predicted sleep obstructive apnea severity. Results. There was a high prevalence of previously undiagnosed obstructive sleep apnea in our sample of patients with treatment-resistant depression. Treatment-resistant depression closed the gap in obstructive sleep apnea prevalence between men and women. Conclusions. We argue that typical symptoms of treatment-resistant depression may overshadow key symptoms of undetected obstructive sleep apnea. Specifically, we found that daytime fatigue masked a potentially significant underlying sleep disorder in women only. Comprehensive assessment and screening for sleep apnea in patients with treatment-resistant is encouraged, and the importance of investigating severity of fatigue in this population is emphasized.
Fine mapping a single nucleotide transversion in AUXIN RESPONSE FACTOR 18 controls prickle absence/presence on various organs in eggplant (Solanum melongena L.)
Authors: Li Shaohang , He Yongjun , Li Dalu , Shi Suli , Wang Yingying , Tang Xin , Liu Yang , Ge Haiyan , Chen Huoying 
Published: July 2022

Abstract
Eggplant is an important fruit vegetable from the Solanaceae family, with rich nutrition and palatability. Prickles covering plant and fruit calyxes of eggplant are considered undesirable agronomic traits, for they bring trouble and create additional costs for farmers. Prickle is a sharp protrusion that is common in plants, but little is known about its regulatory genes and molecular mechanism of morphogenesis. In this study, two eggplant inbred lines, prickly ‘140’ and prickleless ‘145’ were applied to construct F1 , BC1 , and F2 offspring populations. Genetic analysis results showed that prickle’s absence/presence on various organs in eggplant was controlled by only one dominant nuclear gene. The PRICKLE LOCUS ( Pl ) was fine mapped into a candidate interval with 28.3 Kb on chromosome 6 ultimately by adopting bulked segregant analysis combined with genome walking strategy. An auxin response factor SmARF18 ( Smechr0602826.1 ) was deduced to be a reliable candidate gene encoded by Pl , with a non-synonymous SNP (single nucleotide polymorphism) occurring at the 1633rd nucleotide within the second exon, which encoded the middle region of the protein. The finding here could provide a basis to reveal the molecular regulatory mechanism of prickle morphogenesis in plants and breed prickle-free eggplant cultivars.
Evaluating common medications utilized in aneurysmal subarachnoid hemorrhage and association with delayed cerebral ischemia
Authors: Sorrentino Zachary A. , Desai Ansh , Eisinger Robert S. , Maciel Carolina B. , Busl Katharina M. , Lucke-Wold Brandon 
Published: July 2022

Abstract
Background
Spontaneous aneurysmal subarachnoid hemorrhage (aSAH) recovery may be hampered by delayed cerebral ischemia (DCI). Herein, we sought to identify an association of DCI with frequently administered medications in the neurointensive care unit (neuro-ICU).
Methods
In this retrospective study, patients admitted to a tertiary care center neuro-ICU between 2012–2019 with aSAH who could verbalize pain intensity scores were included. Medication dosages and clinical characteristics were abstracted from the medical record. Both paired (within subjects) and unpaired (across subjects) non-parametric analyses were utilized to measure individual DCI risk for a given patient in relation to drug dosages.
Results
119 patients were included; average age was 61.7 ± 15.2 (SD) years, 89 (74.7%) were female, and 32 (26.9%) experienced DCI during admission. Patients with DCI had longer length of stay (19.3 ± 7.4 vs 12.7 ± 5.3 days, p < 0.0001). The combination medication of acetaminophen 325 mg/butalbital 50 mg/caffeine 40 mg (A/B/C; Fioricet®) was associated with decreased DCI on paired (2.3 ± 2.0 vs 3.1 ± 1.9 tabs, p = 0.034) and unpaired analysis (1.84 ± 2.4 vs 2.6 ± 2.4 tabs, p < 0.001). No associations were found between DCI and opioids, dexamethasone, levetiracetam, or acetaminophen. Max and mean daily headache pain was not associated with DCI occurrence.
Conclusion
We identified a dose-response relationship between a commonly administered analgesic and DCI. A/B/C is associated with decreased DCI in this study both within and across subjects, while other medications are not associated with DCI.
Isolation and characterization of a soybean transcription factor, GmDof4.2, improves transgenic tobacco drought tolerance
Authors: Zhai Ying , Chen Jiongxin , He Jiaqi , Zhang Jun , Sha Wei , Yu Haiwei , Zhao Yan , Ma Tianyi , Sun Tianguo , Zhang Meijuan , Li Shanshan 
Published: July 2022

Abstract
DNA binding with one finger (Dof) is a plant-specific transcription factor (TF) that has a key role in seed development and germination, light-mediated control, and plant responses to biotic and abiotic stressors. Herein, we aimed to evaluate the role of the soybean Dof -TFs in plant resistance genetic engineering breeding. In this study, GmDof4.2 was isolated from the soybean. GmDof4.2 in soybean seedlings responded to drought, salt, heat, and cold stressors, according to the results of real-time fluorescence quantitative PCR (qPCR). GmDof4.2 protein had a 59-amino-acid Dof domain with a CX2CX21CX2C motif and four conserved cysteine (Cys) residues, according to the predicted amino acid sequence. The GmDof4.2 protein shared the most genetic similarities with the Cajanus cajan CcDof4 protein. Seven cis-elements associated with stress or hormone induction, as well as two TF binding sites, were found in the GmDof4.2 promoter region. GmDof4.2 protein bound specifically to the AAAG motif in vivo according to the results of yeast one-hybrid. Moreover, the overexpression of GmDof4.2 resulted in higher soluble carbohydrates content and proline content and lower relative electrolyte leakage and malondialdehyde content in transgenic tobacco than in wild-type (WT) tobacco under drought stress. Furthermore, the expression levels of nine stress-related genes were considerably greater in transgenic tobacco than in WT tobacco. The underlined data suggested that the GmDof4.2 improved drought tolerance in transgenic tobacco.
Hypoperfusion of amygdala in chronic migraine: an exploratory quantitative perfusion imaging using 3D pseudo-continuous arterial spin labeling
Authors: Li Xin , Liu Mengqi , Chen Zhiye 
Published: July 2022

Abstract
Background
Amygdala, an essential element of the limbic system, has served as an important structure in pain modulation. Although previous studies have described the structural and functional abnormalities of amygdala in chronic migraine (CM), less is known about the altered perfusion. The study aimed to measure amygdala perfusion in CM with a contrast agent-free and quantitative approach.
Methods
Thirteen CM patients and 15 normal controls were enrolled in the examination, and were performed with conventional brain structural imaging sequences and 3D pseudo-continuous arterial spin labeling (3D-PCASL). The amygdala was used as a seed region to extract volume and cerebral blood flow (CBF) value of all subjects. The correlation analysis and receiver operating characteristic curve (ROC) were used to observe the perfusion changes and explore underlying mechanism of neurolimbic pain-modulation in CM.
Results
Decreased cerebral perfusion of bilateral amygdala was identified in CM (left amygdala, 42.21 ± 4.49 ml/100mg/min; right amygdala, 42.38 ± 4.41 ml/100mg/min) compared with NC (left amygdala, 48.31 ± 6.92 ml/100mg/min; right amygdala, 47.88 ± 6.53 ml/100mg/min). There was no any significant correlation between the perfusion of bilateral amygdala and the clinical variables. And there was no significant difference for the bilateral amygdala volume between two groups. The area under curve (AUC) for the CBF value of left and right amygdala were 0.78 (95%CI 0.58–0.91) and 0.75 (95%CI 0.55–0.89), respectively. The cut-off value was 44.24 ml/100mg/min (left amygdala, with sensitivity 76.90% and specificity 78.70%) and 46.75 ml/100mg/min (right amygdala, with sensitivity 92.3% and specificity 58.80%).
Conclusion
CM presented hypoperfusion in bilateral amygdala, which had potential diagnostic efficacy in discriminating CM from NC. The 3D-PCASL could be considered as a simple and effective tool to identify the perfusion status in migraine.
Prevalence and adverse outcomes of frailty in patients with acute myocardial infarction after Percutaneous Coronary Interventions: a systematic review and meta-analysis
Authors: Yu Qian , Guo Dawei , Peng Jianan , Wu Qifei , Yao Yonghuan , Wang Jiang , Ding Mei 
Published: July 2022

Abstract
Objective
To investigate the prevalence of frailty in patients with acute myocardial infarction after percutaneous coronary intervention and the relationship between frailty and adverse outcomes in patients with acute myocardial infarction after percutaneous coronary intervention.
Methods
We searched relevant studies published from database establishment to October 2021 and performed a meta-analysis using stata12.0 software. A random-effects model was used for I2 greater than > 50%; otherwise, a fixed-effects model was used.
Results
There were 274,976 elderly patients. The degree of frailty was assessed using different frailty assessment tools, the most common of which was the Frailty Index Scale. Nine studies investigated the prevalence of frailty in patients with acute myocardial infarction after PCI, with an overall prevalence of 39% (95% CI: 18%-60%, P < 0.001). Six studies included adverse outcomes in frail patients with acute myocardial infarction after PCI, including all-cause mortality (HR = 2.29, 95%CI:1.65–3.16, P = 0.285), re-hospitalization (HR = 2.53, 95% CI: 1.38–4.63), and in-hospital major bleeding (HR = 1.93, 95% CI: 1.29–2.90,P = 0.825).
Conclusion
In patients with acute myocardial infarction after PCI, the frailty prevalence is increased, especially in STEMI. Frailty patients after PCI, acute myocardial infarction is more likely to be associated with worse clinical outcomes, such as death, bleeding, and re-hospitalization.
The molecular fingerprint of stress resilience
Authors: Wlodarczyk Jakub , Baczynska Ewa , Zareba-Koziol Monika , Ruszczycki Blazej , Krzystyniak Adam , Wojtowicz Tomasz , Bijata Krystian , Pochwat Bartlomiej , Magnowska Marta , Roszkowska Matylda , Figiel Izabela , Masternak Julia , Dzwonek Joanna , Worch Remigiusz , Olszynski Krzysztof , Wardak Agnieszka , Szymczak Piotr , Radwanska Kasia , Jaholkowski Piotr , Hogendorf Adam , Filipkowski Robert , Szewczyk B , Bijata Monika 
Published: July 2022

Abstract
Stress resilience is an ability of neuronal networks to maintain their function despite the stress exposure. In this study, we investigate whether stress resilience is an actively developed dynamic process in adult mice. In order to assess the resilient and anhedonic behavioral phenotypes developed after induction the chronic unpredictable stress, we quantitatively characterized the structural and functional plasticity of excitatory synapses in the hippocampus using a combination of proteomic, electrophysiological, and imaging methods. Our results indicate that stress resilience is a dynamic and multifactorial process manifested by structural, functional, and molecular changes in synapses. We reveal that chronic stress influences palmitoylation, whose profiles differ between resilient and anhedonic animals. We also observed that stress resilience is associated with structural compensatory plasticity of the postsynaptic parts of synapses.
How are university students’ paid work associated with their locus of control?
Authors: Chang Grace 
Published: July 2022

Abstract
This study examines whether university students doing paid work during their studies improves their internal locus of control – the belief in one’s ability to have control over their life events. Using longitudinal data on a cohort of English students, I model students’ locus of control production at age 20/21. I find that engagement in paid work, rather than hours spent in work, is positively associated with students’ internal locus of control. Students who work term-time have 0.12 standard deviations greater internal locus of control than students who do not work, and these estimates are driven by female students. Estimates during the holidays are similar, but smaller in magnitude and statistically insignificant. I do not find any non-linearities in hours of work to skills development. Future studies which examine types of student work may further unpack the gendered differences of work during studies.JEL Codes – J24, J22, I23