bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concomitant splenic artery ligation has no preventive effect on left‐sided portal hypertension following pancreaticoduodenectomy with the resection of the portal and superior mesenteric vein confluence for pancreatic ductal adenocarcinoma
Authors: Gyoten Kazuyuki , Mizuno Shugo , Nagata Motonori , Ito Takahiro , Hayasaki Aoi , Murata Yasuhiro , Tanemura Akihiro , Kuriyama Naohisa , Kishiwada Masashi , Sakurai Hiroyuki 
Published: February 2022

AbstractBackgroundLeft‐sided portal hypertension (LSPH) caused by splenic vein (SV) division in pancreaticoduodenectomy (PD) with portal vein (PV) resection remains challenging. The current study aimed to investigate the efficacy of splenic artery (SA) ligation in preventing LSPH.MethodsOne‐hundred thirty patients who underwent PD with PV resection for pancreatic ductal adenocarcinoma were classified into SV and SA preservation (SVP, n = 30), SV resection and SA preservation (SVR, n = 59), and SV resection and SA ligation (SAL, n = 41). The postoperative incidence of LSPH was assessed.ResultsThe incidence of variceal formation in SVP, SVR, and SAL were 4.8%, 53.2%, and 46.4% at 3 mo, 13.0%, 71.2%, and 62.5% at 6 mo, and 25.0%, 87.5%, and 87.1% at 12 mo, respectively. The rate was significantly higher in SVR at 3 and 6 mo (P = .001 and P < .001, respectively) and in SVR and SAL (P < .001) at 12 mo. Variceal hemorrhage occurred only in SVR (n = 4). The platelet count ratio at 3, 6, and 12 mo began to significantly decrease from 3 mo in SVR (0.77, 0.67, and 0.60, respectively; P < .001) and 6 mo in SAL (0.91, 0.73, and 0.69, respectively; P < .001). The spleen volume ratio also showed significant increase from 3 mo in SVR (1.24, 1.34, and 1.42, respectively; P < .001) and 6 mo in SAL (1.31, 1.32, and 1.34, respectively; P < .001). SVR and SAL were significant risk factors for variceal formation at 12 mo (odds ratio, 21.0 and 20.3, respectively).ConclusionIn PD with PV resection, SAL delayed LSPH but could not prevent its occurrence.
Very small‐scale, segregating‐fluidized‐bed experiments: A dataset for CFD‐DEM validation and uncertainty quantification
Authors: LaMarche W. Casey Q. , Dahl Steven R. , Fullmer William D. , Hrenya Christine M. 
Published: February 2022

AbstractFluidization experiments were conducted on a small scale and with a rapid response (short duration) to enable corresponding simulations at low‐computational cost. Rise times are reported for four or fewer polyethylene particles (intruders) in an air‐fluidized bed of ~5000 group D glass beads. Experimental inputs were completely characterized—particle properties, system dimensions and operating conditions—which is necessary for validating computational fluid mechanics (CFD)‐discrete element method (DEM) including a comprehensive uncertainty quantification (UQ) analysis. Input uncertainties are reported as bounds or cumulative distribution functions of measured values. The staggering number of simulations required to complete a UQ analysis (~O[104] simulations corresponding to ~5 uncertain inputs) motivates this study. These segregating‐bed experiments are designed to permit analogous CFD‐DEM simulations to complete in less than a day on a single (~2.5 GHz) computational processor unit (CPU). Segregation times are reported for several operating conditions, intruder sizes, and initial configurations, providing a rich dataset for numerical model testing, validation and UQ.
Deep Brain Stimulation for Arm Tremor: A Randomized Trial Comparing Two Targets
Authors: Kvernmo Nadja , Konglund Ane E. , Reich Martin M. , Roothans Jonas , Pripp Are H. , Dietrichs Espen , Volkmann Jens , Skogseid Inger Marie 
Published: February 2022

ObjectiveDeep brain stimulation (DBS) of the thalamic ventral intermediate nucleus (VIM) effectively suppresses arm tremor. Uncontrolled studies suggest the posterior subthalamic area (PSA) may be superior. We compared the intra‐individual efficacy of VIM‐ versus PSA‐DBS on tremor suppression and arm function.MethodsWe performed a randomized, double‐blind, crossover trial at Oslo University Hospital in patients (18–80 years) with isolated or combined action tremor affecting at least one arm. Four‐contact DBS leads were implanted (bi‐ or unilaterally) with a trajectory to cover the VIM (upper two contacts) and PSA (lower two contacts). Patients were randomized (1:1 ratio) post‐surgery to: Group 1, VIM‐stimulation months 0–3 (period 1), then PSA‐stimulation months 4–6 (period 2); Group 2, PSA‐stimulation first, then VIM‐stimulation. Primary endpoint was the difference in improvement from baseline to the end of the VIM‐ versus PSA‐period in the sum of the dominant arm tremor scores of the Fahn‐Tolosa‐Marin Tremor Rating Scale (FTMTRS), items 5/6 + 10−14.ResultsForty‐five patients were randomized to Group 1 (n = 23) or 2 (n = 22). In the primary endpoint per‐protocol analysis (mixed model, n = 40), mean difference in the sum FTMTRS score improvement for the dominant arm was −2.65 points (95% CI −4.33 to −0.97; p = 0.002). The difference in favour of PSA stimulation was highly significant in period 2, but not period 1.InterpretationOur randomized trial demonstrated that PSA stimulation provided superior tremor suppression compared with VIM stimulation. A period effect reducing tremor for up to three months in both groups was most likely attributed to a post‐surgery stun effect. ANN NEUROL 2022;91:585–601
Reactive Extrusion Printing for Simultaneous Crystallization‐Deposition of Metal–Organic Framework Films
Authors: Al‐Ghazzawi Fatimah , Conte Luke , Richardson Christopher , Wagner Pawel 
Published: February 2022

AbstractReactive extrusion printing (REP) is demonstrated as an approach to simultaneously crystallize and deposit films of the metal–organic framework (MOF) Cu3btc2 (btc=1,3,5‐benzenetricarboxylate), also known as HKUST‐1. The technique co‐delivers inks of the copper(II) acetate and H3btc starting materials directly on‐surface and on‐location for rapid nucleation into films at room temperature. The films were analyzed using PXRD, profilometry, SEM and thermal analysis techniques and confirmed high‐quality Cu3btc2 films are produced in low‐dispersity interconnected nanoparticulate form. The porosity was examined using gas adsorption which showed REP gives Cu3btc2 films with open interconnected pore structures, demonstrating the method bestows features that traditional synthesis does not. REP is a technique that opens the field to time‐efficient large‐scale fabrication of MOF interfaces and should find use in a wide variety of coating application settings.
Chain extension of thermoplastic polyamide elastomer and its foaming performance
Authors: Ma Yufei , Wen Hui , Xin Chunling , He Yadong 
Published: February 2022

AbstractThermoplastic polyamide elastomer (TPAE) foam material has various important applications, including in shoe materials, cushioning packaging, sports, and automobiles, owing to its excellent resilience and anti‐vibration performance. However, owing to its linear molecular chain structure, the melt viscoelasticity of TPAE is low, making it difficult to obtain lower‐density foamed materials. Therefore, it is crucial to improve the melt strength through chain extensions. Given its ability to react with carboxyl and amine groups, multifunctional epoxides were chosen as chain extenders to increase the melt viscoelasticity of TPAE. A rotational rheometer, differential scanning calorimetry, and Fourier transform infrared spectroscopy were used to characterize the rheological properties and crystallization behavior of the modified TPAE. Adding epoxy‐type chain extender KL‐E4370 was conducive for forming the branch structure of TPAE and even a microgel structure, leading to increased melt viscoelasticity and reduced crystallinity of TPAE. Microcellular TPAE foams (cell sizes and densities of 30 μm and 1.5 × 108 cells cm−3, respectively) were successfully fabricated. With increasing concentrations of KL‐E4370, the foaming temperature zone of TPAE widened and the expansion ratio increased from 5.5 to 9 times, leading to a decrease and an increase in cell diameter and density, respectively, and improvement in the rupture and merging of cells.
Acupuncture for gastrointestinal diseases
Authors: Li Xiang , Liu Shan , Liu Hao , Zhu Jia‐jie 
Published: February 2022

AbstractAcupuncture, an important component of traditional Chinese medicine, has gained growing attention around the world in the past decades. Both manual and electroacupuncture are commonly used in clinical practice, especially by patients with gastrointestinal disorders seeking symptoms control due to disease signs recurrence and/or lack of effective treatments. Currently, patients with functional gastrointestinal disorders, constipation, gastroesophageal reflux disease, inflammatory bowel disease, ileus, acute pancreatitis, and gastroparesis may benefit from acupuncture treatment, as clinically evident, and the most frequently used acupoints are chosen from the large intestine, stomach, bladder, and spleen meridian. The underlying mechanisms of acupuncture involve the neuromodulation, adjustment of gastrointestinal motility and visceral hypersensitivity, anti‐inflammation, repairment of gut microbiota, and intestinal barrier. As methodology advanced, cumulative number of well‐designed clinical trials has been established, which might help elevating clinicians and gastroenterologists' awareness and perception toward application of acupuncture for gastrointestinal diseases management.
Preoperative oncologic therapy and the prolonged risk of venous thromboembolism in resectable pancreatic cancer
Authors: Eurola Annika , Mustonen Harri , Mattila Nora , Lassila Riitta , Haglund Caj , Seppänen Hanna 
Published: February 2022

AbstractBackgroundPancreatic cancer is one of the most prothrombotic cancers. Among patients receiving preoperative chemotherapy followed by surgery, chemotherapy and surgery represent a compound risk for venous thromboembolism (VTE), rendering the postoperative time a period of interest. We aimed to analyze whether preoperative oncologic therapy increases the risk for VTE after surgery and identify which characteristics associate with VTE.MethodsWe first identified patients surgically treated for pancreatic cancer at Helsinki University Hospital between 2000 and 2017, collecting the following data: gender, age at surgery, preoperative medication, body mass index (BMI), preoperative chemo(radio)therapy, tumor size, positive node ratio, perineural and perivascular invasion, tumor grade, surgical technique, postoperative anticoagulation, adjuvant therapy, time of VTE, time of local disease recurrence, time of distant metastasis, and time of death. With a follow‐up period of at least 2 years or until death, we compared a total of 93 preoperative oncologic therapy and 291 upfront surgery patients (n = 384, median age 66.5 years).ResultsPreoperative oncologic therapy increased the risk for thrombosis after surgery (hazard ratio [HR] 1.61; 95% confidence interval [CI] 1.03–2.53). The VTE incidence rate remained high for up to 2 years after surgery. BMI ≥30 kg/m2, prior anticoagulation, and disease recurrence (p < 0.05, respectively) associated with VTE. VTE is also associated with shorter overall survival (HR 3.25; 95% CI 2.36–4.44). In 71.6% (95% CI 60.5–81.1) of patients, VTE was diagnosed after disease recurrence.ConclusionsPreoperative oncologic therapy represents an independent risk factor for VTE, not only during the immediate postoperative period but up to 2 years after surgery. VTE is associated with obesity, prior anticoagulation, and disease recurrence and diminishes overall survival.
Gastric and esophageal cancer in China 2000 to 2030: Recent trends and short‐term predictions of the future burden
Authors: Zhou Jiachen , Zheng Rongshou , Zhang Siwei , Chen Ru , Wang Shaoming , Sun Kexin , Li Minjuan , Lei Shaoyuan , Zhuang Guihua , Wei Wenqiang 
Published: February 2022

AbstractBackgroundGastric and esophageal cancer (GEC) have made a great contribution to the cancer burden in China. This study aims to report GEC incidence and mortality trends in 2000–2015 and their predictions to 2030.MethodsWe collected GEC data from 22 cancer registries for Joinpoint temporal trend analysis between 2000 and 2015 and average annual percent change was calculated. Based on the historical changes, combined with the 2015 GEC national incidence and mortality rate, the rate from 2016 to 2030 was predicted grouped by sex and age. The crude rate, standardized rate, and cumulative rate were calculated. The number of cases were obtained by multiplying the United Nations' World Population Prospects and the predicted rate of corresponding years. Attribution changes between 2015 and 2030 were apportioned into demographics and risk factors.ResultsThere were decreasing trends of age‐standardized incidence rate world (ASIRW) and age‐standardized mortality rate world (ASMRW) during 2000–2015 in China (p < 0.05), the decline was more significant for the age group of 40–49 years in men and the age group of 50–59 years in women. It was predicted that in 2030, about 549,724 new cases and 394,576 deaths of GEC would occur in China. Compared with 2015, the numbers of new GEC cases and deaths in 2030 decreased by 15.24% and 17.62%, respectively. From 2020 to 2030, GEC ASIRW and ASMRW were predicted to decline from 24.98 to 17.47 and from 17.41 to 11.82 per 100,000, respectively. The number of new cases decreased by about 15.24% with changing demographic (44.48%) and risk (−59.72%) and the number of deaths decreased by about 17.62% with changing demographic (47.18%) and risk (−64.80%).ConclusionsAlthough GEC incidence and mortality rates showed downward trends, the disease burden remains heavy in China. The current prevention and control strategy are effective which need to be carried on.
Successful treatment of two extremely premature infants with perinatal tuberculosis and severe sepsis
Authors: Van Nguyen Lam , Huu Dao Nam , Phuong Dang Thuy , Viet Pham Hung 
Published: February 2022

AbstractPerinatal tuberculosis (TB) is a rare disease with severe clinical conditions that may spread to several organs. Early diagnosis to initiate an anti‐TB regimen is key to saving patients. We report the successful treatment of two preterm babies with perinatal TB and sepsis at the National Children's Hospital (NCH), Vietnam.
A 34‐year‐old asymptomatic gossypiboma: A fortuitous diagnosis revealed by appendicular peritonitis: A case report
Authors: Debaibi Mehdi , Sghair Asma , Gabsi Sofien , Nejib Fatma , Sridi Azza , Chouchen Adnen 
Published: February 2022

AbstractGossypiboma is a retained surgical sponge. Patients are usually symptomatic leading to early removal of this entity. We are reporting a 33‐year‐old asymptomatic gossypiboma discovered by appendicular peritonitis on the radiological images. The 64‐year‐old patient underwent a laparotomy with excision of the gossypiboma. The postoperative period was uneventful.
Imaging findings of the primary mucoepidermoid carcinoma of the breast
Authors: Chen Guiwu , Liu Wenqin , Liao Xiaomin , Yu Fenfen , Xie Yuhuan 
Published: February 2022

AbstractMucoepidermoid carcinoma (MEC) is an invasive tumor that has been reported in many organs, such as the salivary glands, lungs, esophagus, and thymus; however, it rarely affects the breast. Here, we report a case of primary breast MEC with imaging, including mammography, ultrasonography, and magnetic resonance imaging.
A systematic literature review of intrusion detection systems in the cloud‐basedIoTenvironments
Authors: Luo Gang , Chen Zhiyuan , Mohammed Bayan Omar 
Published: February 2022

AbstractAs the number of Internet of Things (IoT) subscribers, services, and applications grows, there is a pressing need for a reliable and lightweight security solution that can be used in IoT contexts. Also, due to the open nature of cloud computing, safety concerns are always challenging. One potential solution for this problem is an intrusion detection system (IDS). An ID that utilizes a machine learning method is gaining popularity since it has the benefit of automatically updating to fight against any new form of attack. Due to the importance of IDS in cloud‐based IoT, the main articles and essential techniques in this domain are examined systematically. In cloud‐based IoT, IDSs are categorized into three major categories, including learning‐based, pattern‐based, and rule‐based mechanisms. The findings illustrate that the biggest challenge in IDS is precision and detection, which many researchers are trying to improve. Also, with the rise of connected objects, the most frequently utilized centralized (cloud‐based) IDS struggles with excessive latency and network overhead, leading to delayed detection of unauthorized users and unresponsiveness to assaults. The results will be valuable for academicians, and they can offer visions for future research.
Clover frost‐seeding rate effects on productivity and nutritive value of tall fescue pastures during the year of establishment
Authors: Castillo Miguel S. , Bekewe Perejitei E. , Rivera Raul 
Published: February 2022

AbstractFrost seeding is a low‐cost effective strategy to introduce legumes into existing perennial pastures; however, it has been deemed unreliable in the upper southeast USA. We evaluated frost seeding planting rate effects of clover (Trifolium spp.) during the year of establishment on productivity and nutritive value of clover‐tall fescue [Festuca arundinacea (Schreb.) Darbysh.] pastures. Ball (T. nigrescens Viv.), crimson (T. incarnatum L.), red (T. pratense L.), and white (T. repens L.) clover were frost seeded in the Piedmont and Coastal Plain for 3 yr (2017–2019). Planting rates were 0X, 0.5X, 1X, 1.5X, and 2X of the recommended rate (X) of 5.6, 13.5, 11.2, and 5.6 kg ha–1 for ball, crimson, red, and white clover, respectively. At Coastal Plain, clover accounted for ≤16%. At Piedmont, ball, crimson, red, and white clover accounted for up to 27, 48, 21, and 15%, respectively. Notwithstanding similar clover frequency early in the growing season at both locations, competition from tall fescue in a higher rainfall environment is attributed to the lower clover contribution at Coastal Plain. Increasing clover frost‐seeding rate resulted in greater crude protein (130–154 g kg–1) and total digestible nutrients (586–610 g kg–1) only at Piedmont. The results from this study support the practice of frost‐seeding ball, crimson, red, and white clover at planting rates of 5.6, 20.2, 11.2, and 5.6 kg ha–1, respectively, into tall fescue pastures in the Piedmont; however, minimal or no benefits of frost seeding clover were observed in the Coastal Plain.
Diagnostic accuracy of Thinprep® in cervical lymph node aspiration: Assessment according to the Sydney system
Authors: Uzun Evren , Erkilic Suna 
Published: February 2022

AbstractBackgroundFine‐needle aspiration cytology (FNAC) is a reliable technique that has been used for many years in lymphadenopathy diagnosis. Although conventional smear is the standard approach in FNAC, liquid‐based cytology (LBC) is accepted as an alternative method. Reporting standardization is a significant gap in fine‐needle aspiration cytology, leading to failure in pathologist‐clinician dialog and interobserver variability. In 2020, an expert panel proposed the Sydney system for classifying and reporting lymph node aspiration cytology. This study aimed to evaluate the diagnostic accuracy of LBC in lymph node aspiration cytology under the guidance of the Sydney system.MethodsFive hundred‐four LBC samples were reevaluated and classified according to the Sydney system. Of these, n = 24 were categorized as L1‐inadequate/non‐diagnostic, n = 283 as L2‐benign, n = 36 as L3‐ atypical cells of undetermined significance/atypical lymphoid cells of uncertain significance (AUS/ALUS), n = 48 as L4‐suspicious, and n = 113 as L5‐malignant. Four hundred‐one samples were histopathologically confirmed. The diagnostic accuracy of LBC and the risk of malignancy for each Sydney category were calculated.ResultsThe results were as follows: sensitivity 98.97%; specificity 98.60%; positive predictive value 94.80%; negative predictive value 99.29%; and overall diagnostic accuracy 98.75%. The ROM was 16.6% for L1, 0.7% for L2, 88.8% for L3, and 100% for L4 and L5.ConclusionLBC is suitable for use in lymph node aspiration under the guidance of the Sydney system and has high diagnostic accuracy. Future comprehensive studies will increase the applicability of the Sydney system and minimize interobserver variability.
Physiological control of water exchange in anurans
Authors: Lemenager Lee A. , Tracy Christopher R. , Christian Keith A. , Tracy C. Richard 
Published: February 2022

AbstractResearch on water exchange in frogs has historically assumed that blood osmotic potential drives water exchange between a frog and its environment, but here we show that the “seat patch” (the primary site of water exchange in many anurans), or other sites of cutaneous water uptake, act as an anatomic “compartment” with a water potential controlled separately from water potential of the blood, and the water potential of that compartment can be the driver of water exchange between the animal and its environment. We studied six frog species (Xenopus laevis, Rana pipiens, R. catesbeiana, Bufo boreas, Pseudacris cadaverina, and P. regilla) differing in ecological relationships to environmental water. We inferred the water potentials of seat patches from water exchanges by frogs in sucrose solutions ranging in water potential from 0 to 1000‐kPa. Terrestrial and arboreal species had seat patch water potentials that were more negative than the water potentials of more aquatic species, and their seat patch water potentials were similar to the water potential of their blood, but the water potentials of venters of the more aquatic species were different from (and less negative than) the water potentials of their blood. These findings indicate that there are physiological mechanisms among frog species that can be used to control water potential at the sites of cutaneous water uptake, and that some frogs may be able to adjust the hydric conductance of their skin when they are absorbing water from very dilute solutions. Largely unexplored mechanisms involving aquaporins are likely responsible for adjustments in hydric conductance, which in turn, allow control of water potential at sites of cutaneous water uptake among species differing in ecological habit and the observed disequilibrium between sites of cutaneous water uptake and blood water potential in more aquatic species.