bluuebunny/crossref_metadata_2025_split huggingface dataset:
Des luttes éthiques aux luttes sociales
Authors: Berrebi-Hoffmann Isabelle , Chapus Quentin 
Published: February 2022

Depuis quelques années, les salariés des GAFAM et les contractuels et indépendants de la Tech californienne développent des modes de contestation qui empruntent des formes variées, virtuelles ou physiques sur leur lieu de travail – pétitions, arrêts de travail, marches et manifestations, création de coalitions et collectifs sur les réseaux sociaux, tentatives de syndicalisation. Ces actions collectives regroupent le plus souvent une minorité d’employés, mais reçoivent une attention publique marquée tout en suscitant des réactions fortes des employeurs. Prenant appui sur l’analyse empirique d’un corpus de 275 actions menées au sein du capitalisme High Tech – essentiellement les GAFAM et leurs filiales et sous-traitants – depuis 2015, cet article vise à poser de premières analyses et interprétations de ces mobilisations, inédites par leur ampleur dans la Silicon Valley. Le mouvement de syndicalisation est resitué dans l’histoire syndicale et anti-syndicale des États-Unis. L’hypothèse d’une double convergence de l’action collective que permettrait le capitalisme numérique : entre luttes éthiques et luttes sociales d’une part entre cols blancs et cols bleus d’autre part est avancée. Ces convergences interrogent la façon dont les sciences sociales ont coutume de classer et distinguer entre différents types de mouvements sociaux d’une part et entre différentes formes de critique d’autre part.
Penser le sabotage à l’ère du capitalisme numérique
Authors: Lamoureux Samuel 
Published: February 2022

Cet article propose d’envisager la thèse suivante : le sabotage en tant que pratique de résistance qui consiste à endommager, perturber ou subvertir les opérations d’une machine ou d’une organisation, se retrouve à chaque forme institutionnelle du capitalisme. Trois types de sabotage sont envisagés pour penser cette pratique à l’ère du capitalisme numérique : le sabotage classique, le sabotage subtil et la résistance aux technosciences. Si le premier sabotage tend à disparaître des lieux de travail, le deuxième type consiste plutôt en la réappropriation des outils numériques pour des fins alternatives. La résistance aux technosciences correspond quant à elle au sabotage de l’idéalité cybernétique associée aux nouvelles machines algorithmiques, notamment le droit à la déconnexion et les pratiques de non-usage des technologies numériques.
La justification des pratiques de co-création sur les plateformes de crowdsourcing
Authors: Renard Damien 
Published: February 2022

Les plateformes de crowdsourcing d’idées favorisent le travail de co-création. Pour les internautes, elles se révèlent comme des espaces d’expression reflétant leur pouvoir d’agir. De manière paradoxale, elles peuvent être considérées comme des espaces de mise au travail, la pu-blicisation de l’idée impliquant un transfert de propriété au profit de l’entité organisatrice. L’objectif de cette recherche, basée sur l’analyse empirique d’une plateforme, est de mieux comprendre le système des valeurs et les arrangements mis en œuvre par les acteurs pour justifier leurs pratiques. En nous appuyant sur le modèle conventionnaliste des « Economies de la grandeur » de Boltanski et Thevenot, nous mettons en avant la juxtaposition de différentes cités. Si le principe de rivalité constitue un puissant levier de captation des internautes, le registre de justification de la cité par projets s’impose comme modèle de référence chez les acteurs les plus centraux.
Soins infirmiers en pratique avancée : représentations des acteurs de ce nouveau dispositif
Authors: Aghnatios Matthieu , Darloy Théo , Dictor Julien , Gasparovicova Martina , Drouot Cyril , Gasperini Fabrice , Bouchez Tiphanie 
Published: February 2022

Introduction : Le statut d’infirmier en pratique avancée (IPA) s’inscrit dans la loi en France en 2018. En acquérant des compétences relevant du champ médical, l’IPA suivra des patients volontaires et adressés par un médecin. Une évaluation de l’impact de cette innovation de l’organisation des soins français doit être remise au Parlement français en 2021. Ce travail de recherche a été mené pour recueillir des données visant à accompagner l’implémentation du dispositif et à constituer un point de départ au suivi du dispositif dans le temps. But de l’étude : Explorer les représentations des différents acteurs du dispositif d’IPA pour les maladies chroniques stabilisées en soins primaires, en région Provence-Alpes-Côte d’Azur : patients, médecins généralistes, infirmiers libéraux et étudiants infirmiers en pratique avancée. Résultats : Dans cette étude qualitative prospective par théorisation ancrée, 58 entretiens individuels semi-dirigés ont été menés. Les participants ont exprimé des représentations hétérogènes du rôle de l’IPA. Ils ont fait part d’un flou autour du dispositif et ont exprimé le besoin d’une meilleure communication afin de faciliter son intégration. Le suivi des plans de soins, la prise en charge des patients à domicile, l’éducation thérapeutique et la prévention ont été identifiés comme des besoins auxquels l’IPA pourrait participer. Les zones sous-médicalisées ont été suggérées comme propices à son implémentation. La principale crainte a été le changement de répartition des tâches professionnelles avec le risque de concurrence. L’intégration de l’IPA a été perçue comme plus simple au sein d’établissements de soins car les rôles y sont bien définis avec peu de confusion identitaire entre les acteurs contrairement au milieu libéral. La collaboration entre acteurs de santé a été évoquée comme une condition de réussite du dispositif IPA. Une attitude prudente a été relevée et un besoin de rodage a émergé, les premiers IPA étant considérés comme des précurseurs. Conclusions : La mobilisation des acteurs de santé est un critère de bonne réussite d’intégration de l’IPA, une politique de sensibilisation semble donc nécessaire. La formation des professionnels de santé dans leur cursus ou en formation continue permettrait de développer des compétences collaboratives nécessaires à l’intégration de l’IPA.
Facteurs associés aux barrières d’accès au dépistage du cancer du col de l’utérus à Yaoundé
Authors: Antaon Jesse Saint-Saba , Essi Marie-José , Ngo Um Meka Esther , Mawamba Yvette Nkene , Ndom Paul , Tebeu Pierre-Marie 
Published: February 2022

Introduction : Plusieurs études rapportent que seulement 10 % des femmes à risque de cancer du col de l’utérus ont déjà eu à se faire dépister au Cameroun. Objectif : Cette étude vise à analyser les facteurs qui limitent l’accès au dépistage du cancer du col de l’utérus dans la capitale du pays (Yaoundé). Méthodologie : Il s’agit d’une étude transversale analytique (participée/non-participée), menée du 1 er mai au 10 août 2020. La population d’étude était composée de deux groupes, le groupe sujet, incluant des femmes sans antécédent de dépistage, et le groupe contrôle, composé de femmes ayant bénéficié d’au moins une séance de dépistage. La collecte des données a été réalisée au centre hospitalier universitaire et à l’hôpital gynéco-obstétrique et pédiatrique de Yaoundé. Les données ont été collectées à l’aide d’un questionnaire prétesté et validé, puis analysées à l’aide du logiciel SPSS ® (v. 20). L’analyse par régression logistique a été réalisée pour apprécier l’association entre les différentes variables et la participation au dépistage. Le seuil de significativité était fixé à p < 5 %. Résultats : Sur 300 femmes interrogées, 150 n’avaient jamais participé au dépistage (50 %). En analyse multivariée, les facteurs associés aux difficultés d’accès au dépistage du cancer du col de l’utérus étaient le niveau d’études primaires ([AOR : 5,12 (3,42-7,65)]), le manque d’emploi ([AOR : 5,44 (3,32-8,92)]), le niveau de connaissances insuffisant [AOR : 7,11 (5,70-8,88)]) et l’attitude défavorable ([AOR : 5,58 (4,41-7,06)]). Conclusion : Les facteurs associés au non-dépistage sont multiples. Il est donc nécessaire de développer des stratégies afin d’améliorer l’accès aux services de dépistage du cancer du col de l’utérus au Cameroun.
Impact of Using Flipped Classroom Strategy in Developing the Mathematical Thinking of Pre-Service Teachers in Open Education Systems in Jordan
Authors: Altakhayneh Bahjat Hamid 
Published: February 2022

This study aimed to investigate the impact of the use of the flipped classroom strategy in developing the mathematical thinking of pre-service teachers in the Faculty of Education in open education systems in Jordan. The sample of the study consisted of students enrolled in the program of educational studies for the year 2019/2020 in the open education systems.
To achieve the objectives of the study, the validity and reliability of a mathematical thinking test was verified. The methodology of the study was used in a quasi-experimental design, and the results of the study showed statistically significant differences between arithmetic means of mathematical thinking (α=0.05) in favor of the post mathematical thinking test and showed no statistically significant difference (α=0.05) between the arithmetic means of the employee in the field of education and non-employee in mathematical thinking.
Teaching Medical Students on Surgical Placement during the COVID-19 Pandemic, Lessons Learned so Far
Authors: Evans W. , Noone T. M. 
Published: February 2022

Background: The COVID-19 pandemic has caused significant disruption to the teaching and progression of medical students. With no imminent end to the pandemic, it remains vital that medical students remain integrated into clinical environments to benefit from the teaching opportunities in the hospital setting. Aim: To offer advice on the teaching of medical students undertaking hospital placements within General Surgery during the COVID-19 pandemic. Method: We reflected on our experience as clinical medical educators working through the COVID-19 pandemic, supported by feedback from medical students and relevant contemporary educational guidelines and literature. Results: A review on how to optimise teaching medical students during the COVID-19 pandemic, balancing the need for safety and limiting viral transmission, while maximising clinical experience and learning. Conclusion: The COVID-19 pandemic has forced widespread changes to the way in which medical students receive teaching. We suggest ways to maximise learning opportunities, on hospital placements, during the pandemic. Maintaining quality medical education during the pandemic is key to producing the best doctors of tomorrow.
High-Fat Diet Rapidly Modifies Trafficking, Phenotype, and Function of Plasmacytoid Dendritic Cells in Adipose Tissue
Authors: Stutte Susanne , Ishikawa-Ankerhold Hellen , Lynch Lydia , Eickhoff Sarah , Nasiscionyte Simona , Guo Chenglong , van den Heuvel Dominic , Setzensack Daniel , Colonna Marco , Maier-Begandt Daniela , Weckbach Ludwig , Brocker Thomas , Schulz Christian , Walzog Barbara , von Andrian Ulrich 
Published: February 2022

Abstract
Plasmacytoid dendritic cells (pDCs) display an increased abundance in visceral adipose tissue (VAT) of humans with obesity. In the current study, we set out to decipher the molecular mechanisms of their recruitment to VAT and the functional relevance of this process. We observed increased pDC numbers in murine blood, liver, spleen, and VAT after feeding a high-fat diet (HFD) for 3 wk when compared with a standard diet. pDCs were enriched in fat-associated lymphoid clusters representing highly specific lymphoid regions within VAT. HFD led to an enlargement of fat-associated lymphoid clusters with an increased density and migratory speed of pDCs as shown by intravital multiphoton microscopy. For their recruitment into VAT, pDCs employed P-selectin with E-selectin and L-selectin being only critical in response to HFD, indicating that the molecular cues underlying pDC trafficking were dependent on the nutritional state. Subsequent recruitment steps required α4β1 and α4β7 integrins and engagement of CCR7. Application of fingolimod (FTY720) abrogated egress of pDCs from VAT, indicating the involvement of sphingosine-1-phosphate in this process. Furthermore, HFD altered pDC functions by promoting their activation and type 1 IFN expression. Blocking pDC infiltration into VAT prevented weight gain and improved glucose tolerance during HFD. In summary, a HFD fundamentally alters pDC biology by promoting their trafficking, retention, and activation in VAT, which in turn seems to regulate metabolism.
CANCOL, a Computer-Assisted Annotation Tool to Facilitate Colocalization and Tracking of Immune Cells in Intravital Microscopy
Authors: Pizzagalli Diego Ulisse , Bordini Joy , Morone Diego , Pulfer Alain , Carrillo-Barberà Pau , Thelen Benedikt , Ceni Kevin , Thelen Marcus , Krause Rolf , Gonzalez Santiago Fernandez 
Published: February 2022

Abstract
Two-photon intravital microscopy (2P-IVM) has become a widely used technique to study cell-to-cell interactions in living organisms. Four-dimensional imaging data obtained via 2P-IVM are classically analyzed by performing automated cell tracking, a procedure that computes the trajectories followed by each cell. However, technical artifacts, such as brightness shifts, the presence of autofluorescent objects, and channel crosstalking, affect the specificity of imaging channels for the cells of interest, thus hampering cell detection. Recently, machine learning has been applied to overcome a variety of obstacles in biomedical imaging. However, existing methods are not tailored for the specific problems of intravital imaging of immune cells. Moreover, results are highly dependent on the quality of the annotations provided by the user. In this study, we developed CANCOL, a tool that facilitates the application of machine learning for automated tracking of immune cells in 2P-IVM. CANCOL guides the user during the annotation of specific objects that are problematic for cell tracking when not properly annotated. Then, it computes a virtual colocalization channel that is specific for the cells of interest. We validated the use of CANCOL on challenging 2P-IVM videos from murine organs, obtaining a significant improvement in the accuracy of automated tracking while reducing the time required for manual track curation.
The illusion of a chest wall tumor: a case-report of sternal tuberculosis
Authors: Daniel Morgan , Ricordel Charles , Lorleac'h Aurélien , Norwood James , Richard De Latour Bertrand , Rouzé Simon , Verhoye Jean-Philippe 
Published: February 2022

The incidence rate of tuberculosis in developed countries is low. The most common presentation of this disease is its pulmonary form but with the increasing use of immunosuppressive drugs, extra-pulmonary tuberculosis is re-emerging. Nevertheless, sternal bone involvement is uncommon. We report the case of an eighty-three-year-old man who presented a painful sternal mass which progressed towards cutaneous ulceration. The first diagnostic hypothesis was neoplasia. The pathological and microbiological diagnosis of tuberculosis was achieved after surgical biopsy. The patient received treatment against tuberculosis for nine months enabling recovery without surgery. This case illustrates the importance of having a diagnosis prior to any kind of treatment facing any voluminous parietal thoracic lesions. This diagnosis is made possible by surgical samples and interdisciplinary teamwork. This case underlines that tuberculosis remains a differential diagnosis that must be evoked in case of unusual bone mass.
Cardiac monitoring during trastuzumab therapy in metastatic breast cancer: early incidence of cardiac dysfunction
Authors: Perone Francesco , Zamora Auñon Pilar , Rodríguez Laura , Vinal David , Caro-Codon Juan , Pertejo Ana , Martínez Marín Virginia , Espinosa Enrique , López-Fernández Teresa 
Published: February 2022

Trastuzumab therapy has dramatically changed breast cancer prognosis. Consensus documents recommend a close monitoring during therapy, not always feasible, especially in metastatic breast cancer. The purpose of this study is to describe trastuzumab cardiotoxicity in metastatic breast cancer patients to understand how to improve cardiovascular monitoring. We retrospectively studied metastatic breast cancer patients scheduled for trastuzumab therapy (2001-2018). All patients underwent a baseline evaluation and monitoring during therapy. Cardiotoxicity was defined as symptomatic heart failure or asymptomatic decrease in left ventricular ejection fraction > 10% from baseline and < 53%. Ninety-two women were included, mean age 61 years (±14.43), median follow-up 42.5 months (IQR 26-74). Fourteen percent developed cardiotoxicity: two heart failure with preserved left ventricular ejection fraction, three heart failure with reduced left ventricular ejection fraction, and eight asymptomatic decreased in left ventricular ejection fraction. Eighty-one percent of cardiac dysfunction cases occurred within the first 4 years and on median of 31 months from trastuzumab initiation. Thus, in metastatic breast cancer patients, trastuzumab-mediated cardiotoxicity occurred more frequently during the first 4 years. These data should be considered to optimize follow-up protocols.
Mental Status in Patients with Cerebral Infarction in Central China at the Early Stage of Coronavirus Disease-19 Pandemic
Authors: Wu Yuping , Ma Sha , Zhang Hong , Huang Xiaoqian , Shu Yi 
Published: February 2022

Aims:
The study aimed to analyze the changes in mental health and social support in patients with cerebral infarction during the recovery period at the early stage of coronavirus disease pandemic.

Subjects and Methods:
During January–March 2020, 98 patients with cerebral infarction during the recovery period were selected from Wuhan city. Among them, 42 patients were living alone (called the solitary group) and 56 patients lived with their spouses (called the spouse group). The Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) were used to evaluate anxiety and depression, respectively, and Multi-Dimensional Scale of Perceived Social Support (MSPSS), social support for patients.

Statistical Analysis Used:
The statistical calculations were carried out using GraphPad Prism 5.01 software (GraphPad, San Diego, California, USA).

Results:
At the early stage of the pandemic, patients with cerebral infarction in the solitary group and the spouse group experienced varying degrees of anxiety and depression. The SAS and SDS scores in the solitary group were significantly higher than those in the spouse group (P < 0.01). The subscale scores of MSPSS in the solitary group were lower than those in the spouse group (P < 0.01).

Conclusions:
It is necessary for medical staff to help the patients to overcome anxiety and depression and provide more social support to patients, especially for those patients living alone.
Determining the optimum tumor control probability model in radiotherapy of glioblastoma multiforme using magnetic resonance imaging data pre- and post- radiation therapy
Authors: Banisharif Shabnam , Shahbazi-Gahrouei Daryoush , Akhavan Ali , Rasouli Naser , Shahbazi-Gahrouei Saghar 
Published: February 2022

Background:
Glioblastoma multiforme (GBM) is the most common and malignant brain tumor. The current standard of care is surgery followed by radiation therapy (RT). Radiotherapy treatment plan evaluation relies on radiobiological models for accurate estimation of tumor control probability (TCP). This study aimed to assess the impact of obtained magnetic resonance imaging (MRI) data before and 12 weeks after RT to achieve the optimum TCP model to improve dose prescriptions in radiation therapy of GBM.

Materials and Methods::
In this quasi-experimental study, MR images and its relevant data from 30 patients consisting of 9 females and 21 males (mean age of 46.3 ± 15.8 years) diagnosed with GBM, whose referred for radiotherapy were selected. The data of age, gender, tumor size, volume, and signal intensity using analysis of MRI data pre- and postradiotherapy were used for calculating TCP. TCP was calculated from three common radiobiological models including Poisson, linear quadratic, and equivalent uniform dose. The impact of some radiobiological parameters on final TCP in all patients planned with three-dimensional conformal radiation therapy was obtained.

Results:
A statistically significant difference was found among TCP in Poisson model compared to the other two models (P < 0.001). Changes in tumor volume and size after treatment were statistically significant (P < 0.05). Different combinations of radiobiological parameters (α/β and SF2 in all models) observed were meaningful (P < 0.05).

Conclusion:
The results showed that among TCP radiobiological models, the optimum is the Poisson. The results also identified the importance of TCP radiobiological models in order to improve radiotherapy dose prescriptions.
Renal function markers in single-kidney patients after percutaneous nephrolithotomy
Authors: Ghadian Alireza , Einollahi Behzad , Ebrahimi Mehrdad , Javanbakht Mohammad , Asadi Mousa , Kazemi Reza 
Published: February 2022

Background:
The present study was performed to investigate and compare renal functions of single-kidney patients after 12 h of percutaneous nephrolithotomy (PCNL) surgery through assessing major markers of renal function with focus on serum level of cystatin that performs a consistent accuracy in various conditions.

Materials and Methods:
This pilot quasi-experimental study was done on 92 patients with single kidney having staghorn calculus who had undergone PCNL and were referred to the Al-Zahra Hospital, Isfahan, Iran, during 2019–2021. Serum levels of cystatin C, creatinine, estimated glomerular filtration rate (eGFR), and neutrophil gelatinase-associated lipocalin (NGAL) urine level were evaluated before and 12 h after surgery.

Results:
The mean cystatin C decreased significantly 1.58 ± 0.55 versus mg/L 1.46 ± 0.52 after 12 h after surgery (P < 0.001). Furthermore, the mean levels of creatinine (2.04 ± 0.71 vs. 1.89 ± 0.60 mg/dL) and NGAL (39.72 ± 12.87 vs. 24.05 ± 10.89 μg/ml) were decreased significantly after 12 h of procedure (P < 0.05) while the mean eGFR (57.62 ± 27.59 vs. 64.68 ± 31.88 ml/min/1.73 m2) was increased significantly after 12 h (P < 0.001).

Conclusion:
Due to significant improvement in all markers of renal after PCNL, this procedure can be considered a potentially effective and safe approach for treating large stone in single-kidney patients.
Consumption and utilization of fruits, leaves, and seeds of cola (pachycarpa and lepidota) in two southeastern States of Nigeria
Authors: Ngoka` I.R. , Chikwendu J.N. , Maduforo A.N. 
Published: February 2022

Background: Cola pachycarpa and Cola lepidota are two varieties of fruit known as Monkey cola. They are from the same plant family. The plant was predominantly found in the wild until recently. There is basic information on the leaves, seeds, and fruits of this plant. However, there is paucity of empirical studies on their consumption and utilization pattern.
Objective: The study evaluated the consumption and utilization pattern of the leaves, fruits and seeds of these two varieties of Monkey Cola, pachycarpa and lepidota in two South-Eastern States of Nigeria.
Materials and methods: The study adopted a cross-sectional survey. The survey employed a multi-stage random sampling technique to select 808 adults from different communities in Isiala Mbano local government area of Imo State and Isiala Ngwa South local government area of Abia State. A structured validated questionnaire was used to obtain information on consumption and utilization pattern of the fruits, leaves and seeds in the survey areas. Data was analysed statistically using IBM-SPSS (Special Package for Social Sciences) version 20 software.
Results: Cola pachycarpa was more popular (84.5%) and the fruits were consumed mainly raw (99.0%). The leaves and seeds are not eaten but used for medicinal purposes, though the seeds ranked highest in this regard (48.3%).
Conclusion: The fruits particularly Cola pachycarpa were popular. They were consumed raw while the leaves and seeds were solely used in traditional medicine.