bluuebunny/crossref_metadata_2025_split huggingface dataset:
Plasma gasification of municipla solid waste to produce high H2 syngas
Authors: Dong Kun , Chen Song , Guo Zhenfei , Chu Chu , Chen Guanyi , De Filippis Paolo , de Caprariis Benedetta , Ma Wenchao 
Published: October 2022

Abstract
Thermal plasma gasification has been demonstrated as one of the most effective and environmentally friendly methods for MSW treatment. In this study, experiments were carried out in a 30 kW direct current thermal plasma gasification system, specifically focusing on the influence of feedstock type, steam/carbon ratio, running power and continuous feed rate on the product characteristics. As the S/C ratio increased, the H2 yield increased firstly and then decreased and reached the maximum value of 36.42 mol/kg at the S/C ratio of 0.84 while the H2 content continued to grow from 59.87–61.04%. The H2 proportion in syngas and H2 yield both showed a steady rise trend with the increase of running power. Continuous feeding method was conductive to the promotion of syngas LHV. Compared with other conventional technologies, plasma gasification exhibits superior capacity of H2 production (H2 proportion of 60.34 vol.% and H2 yield of 39.77 mol/kg).
Wildfires In Australia: A Bibliometric Analysis and A Glimpse On ‘Black Summer’ (2019/20) Disaster
Authors: Haque K M Shamsul , Uddin Minhaz , Ampah Jeffrey , Haque Kamrul , Hossen Shahadat , Rokonuzzaman Md , Hossain Yeamin , Hossain Sazzad , Rahman Zillur 
Published: October 2022

Abstract
A wildfire, an unplanned fire that is largely uncontrolled and originates in combustible vegetation in rural or urban settings, is one of the most pervasive natural catastrophes in some areas, such as Siberia, California, and Australia. Many studies, such as standard reviews, have been undertaken to look into the works of literature on wildfires or forest fires and their effects on aquatic and terrestrial ecosystems. Regrettably, conventional literature reviews failed to identify the important researchers, evolving complexities, emerging research hotspots, trends, and opportunities for further research on the ground of wildfire study. The present study employs bibliometric analysis to investigate this study area qualitatively and quantitatively. The Scopus database systems and Web of Science Core Collection yielded 78 qualifying papers, which were then evaluated using Biblioshiny (A bibliometrix tool of R-studio). According to the statistics, the discipline is expanding at a pace that is 13.68 percent faster than average. So far, three key periods of transformation have been documented: preliminary evolution (8 articles; 1999–2005), gentle evolution (14 articles; 2006–2013), and quick evolution (56 articles; 2014 to 2021). FOREST ECOLOGY AND MANAGEMENT and SCIENCE journals have the highest number of publications, accounting for 7.70% of total wildfire-related articles published from 1999 to 2021. However, recent data indicate that investigators are shifting their focus to wildfires, with the term AUSTRALIA having the highest frequency (91) and WILDFIRE having the second highest (58) as the most appeared keywords. The present study will provide a foundation for future research on wildfire incidence and management by receiving information by synthesising previously published literature in Australia and around the world.
Identification and Validation of Hub Genes in Uterine Corpus Endometrioid Carcinoma
Authors: LI JIANQI , HUANG YANFANG , SHENG XIUJIE 
Published: October 2022

Abstract
Uterine Corpus Endometrioid Carcinoma (UCEC) is one of the malignant tumors with high incidence of female reproductive system. Despite significant progress in molecular biology research and treatment of UCEC, the molecular mechanisms of UCEC tumorigenesis have not been fully elucidated. The purpose of this research was to identify differentially expressed genes (DEGs) association with the pathogenesis of UCEC, and to further define available prognostic biomarkers and immunotherapy targets for UCEC. RNA expression datasets and clinical data for UCEC patients were collected from the UCSC Xena database and The Cancer Genome Atlas (TCGA) database. 174 UCEC tissues and 23 normal endometrial tissues were screened using PCA and LIMMA methods. Analysis of GO enrichment indicated that the up-regulated DEGs were mainly involved in tissue development, cell cycle regulation and epithelial development. Subsequently, DEGs was identified by weighted gene co-expression network analysis (WGCNA). DEGs in blue modules were determined to be significantly positively correlated with UCEC, conversely, black modules were significantly negatively correlated with UCEC. Finally, 16 genes were identified by WGCNA, and further Kaplan-Meier (KM) analysis revealed that 5 of the 16 genes were significantly negatively correlated with overall survival (OS) namely hub genes, including AURKA, CCNE1, IQGAP3, TTK and UBE2C. Further, the expression of hub gene was verified by GEO dataset and IHC analysis in the Human Protein Atlas. Finally, potential immunotherapeutic targets and approaches were revealed by calculating immune scores for immune infiltration, immune cell infiltration, and immune cell regulator across the 5 hub genes. In conclusion, In conclusion, this study probed into the molecular mechanisms of UCEC development in depth, and identifies 5 promising prognostic biomarkers and immunotherapy targets in UCEC progression, providing directions for the treatment of UCEC.
Palliative Care Stay Room – designing, testing and evaluating a gamified social intervention to enhance palliative care awareness.
Authors: Reigada Carla , Sandgren Anna , Rivas Sonia , Carvajal Ana , Hermida-Romero Santiago , Benítez Edgar , Ripoll Guillen , Olza Inés , Centeno Carlos , Gómez Beatriz 
Published: October 2022

Abstract
Introduction: The message of palliative care can be promoted using creative thinking and gamification. It can be an innovative strategy to promote changes in behaviour, promote thinking, and work on skills such as empathy.
Aim: Design, test and evaluate a gamified social intervention to enhance palliative care awareness.
Methods: Participatory action research study with mixed methods, Design Thinking and using the Public Engagement strategy. Forty-three undergraduate students participated in a Palliative CareStay Room and completed the Test of Cognitive and Affective Empathy (TECA) before and after the game. At the end of the game, a ten-minute debriefing was held with the participants and an open-ended questionnaire was handed out. The content analysis was done independently and the sum of the scores of each dimension was compared before and after the activity.
Findings: Older participants (N=43: female=23; male=20; x̄ 19.6 years old) presented higher values in perspective adoption (intellectual ability to put oneself in the other’s place) p=.046 and in emotional understanding (ability to recognize emotional states) p=.018, after participating in the game. Females had the highest scores on empathic joy (p=.08). Students stated that the game gave them knowledge and new perspectives.
Conclusion: Gamification can be used in teaching and transmitting positive attitudes in Palliative Care and can help young university students to think positively about care issues.
Mailing human papillomavirus self-sampling kits to women under-screened for cervical cancer improved participation in cervical cancer screening in a general population study in Japan
Authors: Nishimura Yoko , Matsuura Motoki , Terada Noriko , Nagao Sachiko , Shimada Hiroshi , Isoyama Kyoko , Tamate Masato , Iwasaki Masahiro , Saito Tsuyoshi 
Published: October 2022

Abstract
Background
One cause of the increase in cervical cancer rates in Japan is the long-term stagnation in the cervical cancer screening consultation rate. Improving the screening consultation rate is therefore of urgent concern to reduce cervical cancer incidence. Self-collected human papilloma virus (HPV) tests have been successfully adopted in several countries, such as Netherlands and Australia, as a measure of individuals who have not undergone cervical cancer screening in national programs. This study aimed to verify whether self-collected HPV tests presented an effective countermeasure for individuals who had not undergone the recommended cervical cancer screenings.
Methods
This study was conducted from December 2020 to September 2022 in Muroran City, Japan. The primary evaluated endpoints included the percentage of citizens with positive self-collected HPV test results and individuals who underwent cervical cancer screening at a hospital. The secondary endpoints were the percentage of included participants who had undergone any cervical cancer screening and the diagnostic rates.
Results
The included study participants were 7,653 individuals aged 20–50 years with no record of having undergone a cervical cancer examination in the past 5 years. We mailed these participants information on self-administered HPV tests as an alternative screening procedure and sent the kit to 1,674 women who requested the test, among whom 953 returned the kit. Among the 89 HPV-positive individuals (positive rate, 9.3%), 71 (79.8%) visited the designated hospital for an examination. A closer examination revealed that 13 women (18.3% of hospital visits) had a cervical intraepithelial neoplasia (CIN) finding of CIN2 or higher, among whom one each had cervical cancer and vulvar cancer, eight presented with CIN3, and three presented with CIN2; two cases of invasive gynecologic cancer were also identified.
Conclusions
We conclude that the self-collected HPV tests showed a certain efficacy as a measure of individuals who had not undergone the recommended cervical cancer screening. We devised ways to have the unexamined patients undergo HPV testing and ensure that HPV-positive individuals visited the hospital. Despite a few limitations, our findings suggest the effectiveness of this public health intervention.
Association Between Cognitive Impairment and Motor Dysfunction among Patients with Multiple Sclerosis
Authors: AlHarthi Hanadi , Almurdi Muneera Mohammed 
Published: October 2022

Abstract
Objectives: 1. To study the association between cognitive impairment (CI) and motor dysfunction (MD) among patients with MS. 2. To examine if muscle weakness, motor incoordination, balance impairment, gait abnormalities, and/or increased fall risk can be adopted as indicator of CI in patients with MS.
Methods: Seventy patients with multiple sclerosis were included in this cross-sectional study. They underwent assessment of cognitive impairment using the Montreal Cognitive Assessment Scale (MoCA), muscle strength using the Handheld dynamometer, balance, gait, and fall risk assessment using Tinetti scale. Moreover, motor coordination was assessed for both upper and lower extremities through the Timed Rapid Alternating Movement for Upper Extremity and Timed Alternate Heel-to-Knee Test for lower extremity.
Results: A Significant association was found between CI and motor coordination, balance, gait, and risk of fall (p< 0.005) apart from muscle strength. Stepwise multiple linear regression showed that 22.7% of the variance in the MoCA was predictable from the fall risk and the incoordination of upper extremity among MS population.
Conclusion: CI is significantly associated with motor incoordination, balance impairment, gait abnormality, and increased fall risk. Furthermore, the risk of fall and upper extremity incoordination appeared as the best indicators of CI among patients with MS.
Spatial distribution, sources, and risk assessment of metal ions in sediments from industrial areas in the Kuye River Basin in Shenmu, China
Authors: Wang Zhu , Liu Yong Jun , Wei Chun Xiao , Liu Xing She , Yang Zhuang Zhuang , Yang Lu , Zhang Ai Ning , Li Zhi Hua 
Published: October 2022

Abstract
Metal pollution of river sediments in industrial areas has attracted widespread attention. In this study, 11 metal ions (including Fe, Al, Ag, Mn, Cd, Cr, As, Cu, Pb, Zn, Ni) were determined and analyzed in river sediments of typical industrial areas in the Kuye River Basin, a first-level tributary of the Yellow River. The geological accumulation index, enrichment factor, and pollution load index indicated that the metal ions in this area were enriched and polluted to different degrees. The spatial distribution of the 8 kinds of heavy metals showed that the content in the upstream and downstream was higher, and the middle reaches were lower. the heavy metals mainly came from local industrial activities, coal mining and transportation, and soil weathering, Human activities were the main reasons for the dramatic spatial changes and high levels of heavy metals. The results of the combined potential ecological risk index and sediment quality guidelines showed that the ecological risk downstream of the area was high, and Ni and Pb have caused adverse biological reactions. The human carcinogenic risk assessment result showed that the non-carcinogenic hazard quotient of metal ions in the study area was at an acceptable level, but the carcinogenic risk level of Ni and Cr was higher than 10-4, which was an unacceptable level and must be got enough recognition. The results of this study can provide theoretical support for the pollution control and environmental restoration of rivers in energy-enriched areas.
Identification and validation of quantitative trait loci for fertile spikelet number per spike and grain number per fertile spikelet in bread wheat (Triticum aestivum L.)
Authors: Jiang Cheng , Xu Zhibin , Fan Xiaoli , Zhou Qiang , Ji Guangsi , Chen Liangen , Yu Qin , Liao Simin , Zhao Yun , Feng Bo , Wang Tao 
Published: October 2022

Abstract
Fertile spikelet number per spike (FSN) and grain number per fertile spikelet (GNFS) contribute greatly to wheat yield improvement. To detect quantitative trait loci (QTL) associated with FSN and GNFS, a recombinant inbred line (RIL) population derived from the cross of Zhongkemai 13F10 and Chuanmai 42 was employed across eight environments. Two Genomic regions associated with FSN were detected on chromosomes 2A and 6A using bulked segregant exome sequencing (BSE-Seq) analysis. Based on the constructed genetic linkage map, four QTL QFsn.cib-2A, QFsn.cib-6A, QGnfs.cib-2A and QGnfs.cib-6A were identified in three or more environments. Among them, two major QTL QFsn.cib-2A (LOD=4.67–9.34, PVE=6.66–13.05%) and QGnfs.cib-2A (LOD=5.27–11.68, PVE=7.95–16.71%) were detected in seven and six environments, respectively. They were co-located in the same region, namely QFsn/Gnfs.cib-2A . This locus was further verified by the linked Kompetitive Allele Specific PCR (KASP) markers in a different genetic background. QFsn/Gnfs.cib-2A showed pleiotropic effects on grain number per spike (GNS) and spike compactness (SC) and had no effect on grain weight. Since QFsn/Gnfs.cib-2A might be a new locus, it and the developed KASP markers can be used in wheat breeding. According to haplotype analysis, QFsn/Gnfs.cib-2A was identified as a target of artificial selection during wheat improvement. Based on haplotype analysis, sequence differences, spatiotemporal expression patterns and gene annotation, TraesCS2A03G0978700 was predicted as the potential candidate gene for QFsn/Gnfs.cib-2A . These results provide valuable information for fine mapping and cloning gene(s) underlying QFsn/Gnfs.cib-2A.
Food habits and attitudes among Norwegian medical students
Authors: Sanne Ingebjørg , Bjørke-Monsen Anne-Lise 
Published: October 2022

Abstract
Background:
Dietary patterns and beliefs are influenced by medical advice, social media and marketing. Medical doctors are expected to provide correct, updated and non-biased nutritional advice to their patients, but their own dietary habits and food attitudes may influence nutritional counselling.
Methods:
We have investigated dietary habits and food attitudes among students at the Medical Faculty, University of Bergen, Norway, by using an anonymous survey.
Results:
Of the 880 students, 394 responded to the survey. Although 90% of the students were omnivores, the majority had a negative attitude towards meat, and considered fish to be healthier than meat. Significantly more women than men reported use of a special diet and excluded meat from their diet, even if they were omnivores. The most frequently used supplement was cod liver oil or omega 3 fatty acids.
Conclusion:
The medical students’ diet and food attitudes not only reflect current health recommendations, but also popular beliefs and marketing in Norway. Curriculum planners should make the students capable of recognizing the influence of social media, marketing and medicine-food industry interactions, to ensure relevant nutrition knowledge for future doctors.
Physical activity moderates the association between negative life events and depression symptom in newlyweds: a large multicenter cross-sectional study
Authors: Liao Tierong , Tang Yanlan , Yang Xinliu , Gao Yaya , Liu Yuwei , Zhu Peng , Tao Fangbiao , Shao Shanshan 
Published: October 2022

Abstract
Background Previous studies have showed that negative life events can increase the risk of depression, but little research have focused on how to improve this risk, especially for the newlyweds population——be about to breed next generation. We aim to investigate whether physical activity (PA) moderates the association between negative life events and depression symptom in a large sample of newlyweds.
Methods This study consisted of 28898 newlywed women and 30431 newlywed men collected from April 2019 to June 2021 in Anhui Province of China. International Physical Activity Questionnaire Short Form and Patient Health Questionnaire were used to assess participants' PA levels in the past week and depression state in the past two weeks, respectively. Multivariate logistic regressions were applied to examine the associations of negative life events over the past year and depression symptom. Two-factor analysis of variance was used to analysis the interaction of stressful life events and physical activity on depression scores.
Results Among the 28898 newlywed women, the prevalence of depression symptom and negative life events were 27.4% and 71.4%, respectively. Women experienced negative life events (odds ratio[OR]= 2.81, 95% CI 2.63–3.01) were related with higher risk of depression symptoms. Moderate or high physical activity level was associated with lower odds of depression symptom for women with negative life events. Besides, physical activity moderates the association between negative life events and depression scores (P for interaction < 0.05). Similar results were found in newlywed men.
Conclusions The findings indicate that high or moderate physical activity levels can weaken the association between negative life events and depression symptom. Improving the level of physical activitycould be a strategy by which to prevent depression symptom for the newlyweds with negative life events.
3L, three-Lactobacilli on recovering of microbiome and immune-damage by cyclophosphamide chemotherapy
Authors: Yue Shousong , Zhang Zhenzhong , Bian Fei , Zhang Yan , Chen Gao , Zhu Youfeng , Li Jun , Picimbon Jean-François 
Published: October 2022

Abstract

Background We examined the impact of using a probiotic containing three differentLactobacilli(3L) on the gut microbiome of rats following cyclophosphamide (CTX) treatment. CTX corresponded to chemotherapy which is used for human cancer treatment and known to have adversive effects on the immune system. Methods We conducted our experiment with ten rats in five different experimental groups which included control, CTX treated, and then low, medium, and high probiotic treatment with CTX treatment. Of these ten rats in each group, we sequenced the stool of three of them using both ITS and 16S sequencing. We then went on to examine the taxonomic composition of these samples to determine whether probiotic treatment helped the rat’s microbiome return to similar structure as the control rats. Results We used Illumina MiSeq sequencing to generate sequencing data from microbial genomic DNA libraries, which is useful for testing the effects of 3L on bacteria and fungi. Microbiome analysis, phylogenetic and classification reports, and community data have all backed up the experiments and findings that 3L had a significant positive impact on the microbiome. Furthermore, the effect on specific metabolic pathways aids in deriving the study’s conclusion (use of 3L in chemotherapy) to the mode of action, mechanistically by correcting microbiota composition and enhancing specific gut metabolic functions. Conclusions Through experimental results using anin vivomodel, we suggested the role of novel natural probiotics 3L, 3 Lactobacilli in the establishment of a strong and sustainable beneficial healthy gut flora, after CTX chemotherapy. We suggested some new adjuvants to chemotherapy as drugs + lactobacillustreament using the rat CTX model (immunosuppression caused by cyclophosphamide). Furthermore, in numerous studies that reported the use of probiotics involvingLactobacillusin post-chemo or post-surgical procedures, we proposed a new probiotic formulation (L. acidophilus + L. casei + L. plantarum) to be further studied and explored in the prevention of health condition loss by alteration of the general immune system.
The antennal transcriptome of Triatoma infestans reveals substantial expression changes triggered by a blood meal
Authors: Estivalis Jose Manuel Latorre , Traverso Lucila , Pontes Gina , Lorenzo Marcelo Gustavo 
Published: October 2022

Abstract
Background
Triatoma infestans is the main vector of Chagas disease in the Americas, currently transmitting it in Argentina, Paraguay, and Bolivia. Many T. infestans populations present insecticide resistance, reducing the efficiency of control campaigns. Alternative vector control methods are needed, and molecular targets mediating fundamental physiological processes can be a promising option to manipulate kissing bug behavior. Therefore, it is necessary to characterize the main sensory targets, as well as to determine whether they are modulated by physiological factors. In order to identify gene candidates potentially mediating host cue detection, the antennal transcripts of T. infestans fifth instar larvae were sequenced and assembled. Besides, we evaluated whether a blood meal had an effect on transcriptional profiles, as responsiveness to host-emitted sensory cues depends on bug starvation.
Results
The sensory-related gene families of T. infestans were annotated (127 odorant receptors, 38 ionotropic receptors, 11 gustatory receptors, 41 odorant binding proteins, and 25 chemosensory proteins, among others) and compared to those of several other hemipterans, including four triatomine species. Several triatomine-specific lineages representing sensory adaptations developed through the evolution of these blood-feeding heteropterans were identified. As well, we report here various conserved sensory gene orthogroups shared by heteropterans. The absence of the thermosensor pyrexia, of subfamily IV and VII pickpocket receptors, together with clearly expanded takeoutrepertoires, are revealed features of the molecular bases of heteropteran antennal physiology. Finally, out of 2122 genes whose antennal expression was significantly altered by the ingestion of a blood meal, a set of 41 T. infestans sensory-related genes (9 up-regulated; 32 down-regulated) is detected.
Conclusions
We propose that the set of genes presenting nutritionally-triggered modulation on their expression represent candidates to mediate triatomine host-seeking behavior. Besides, the triatomine-specific gene lineages found represent molecular adaptations to their risky natural history that involves stealing blood from an enormously diverse set of vertebrates. Heteropteran gene orthogroups identified represent an unknown feature of the sensory specificities of this largest group of hemipteroids. Our work is the first molecular characterization of the peripheral modulation of sensory processes in a non-dipteran vector of human disease.