bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychological distress and associated factors among patients attending orthopedic unit, Dilla university referral hospital, Dilla, Gedeo zone, South Ethiopia 2021
Authors: Ababu Henok , Kassaw Chalachew , Sileshy Bethelhem 
Published: May 2022

Abstract
BackgroundPsychological discomfort is a state of emotional distress caused by everyday stressors and obligations that are difficult to manage. It's one of the most common mental health problems on the planet. The physical status of a person has an impact on his or her psychological well-being, and if not handled well, it will eventually have an impact on his or her well-being. Orthopedic trauma has a wide range of effects on survivors' physical health, as well as a variety of mental health concerns that impede recovery. Psychiatric problems and behavioral abnormalities are 3–5 times more common in people who have been harmed, and they are a predictor of poor outcomes. It is crucial to begin further therapies as soon as possible.MethodsA cross-sectional study was undertaken at Dilla University Referral Hospital on an institutional basis. The data was collected via a face-to-face interview and the Kessler psychological distress scale (K-10) was used to assess psychological distress. A total of 366 people were chosen using simple random selection. SPSS21 was used to enter and evaluate the data. To find related factors, bivariate and multivariate logistic regressions were used. Variables having a p-value of less than 0.05 were deemed statistically significant.ResultOut of all respondents, 114 (31.4%) of the individuals have experienced psychological anguish. Independent variables such as being female (adjusted odds ratio (AOR = 5.8, 95 percent CI (3.5–11.1), being under 27 years old (AOR = 2.34, 95 percent CI (1.89–3.68), being unable to read and write educational status, married (adjusted odds ratio (AOR = 2.67(1.24–5.34), poor social support (AOR = 1.4, 95 percent CI (1.21–2.89), and poor sleep quality (AOR = 1.5, 95 percent).ConclusionThe prevalence of psychological distress was high. Being female, having poor social support, and having a high PSQI score were significantly associated factors with psychological distress. It is good if clinicians emphasize orthopedic patients especially females and those having poor social support and low sleep quality symptoms.
Fruits and vegetables intake improves birth outcomes of women with gestational diabetes mellitus and hypertensive disorders of pregnancy
Authors: Sewor Christian , Obeng Akua A. , Eliason Sebastian , Agbeno Evan K. , Amegah A. Kofi 
Published: May 2022

Abstract
Background
Disorders of pregnancy such as hypertensive disorders of pregnancy (HDP) and gestational diabetes mellitus (GDM) have been associated with adverse birth outcomes. However, to date, no study has explored the ameliorating role of maternal nutrition in the relationship between disorders of pregnancy and adverse birth outcomes. We investigated the relationship between HDP and GDM, and adverse birth outcomes in a Ghanaian population and evaluated the ameliorating role of fruit and vegetable consumption in the relationship.
Methods
We conducted a cross-sectional study among 799 mothers who had recently delivered singletons in the Cape Coast Metropolis, Ghana. Information on HDP and GDM, and birth outcomes were retrieved from the maternal health book of the mothers. A food frequency questionnaire was used to assess fruit and vegetable intake during pregnancy. Multivariable binary logistic regression was used to investigate the association between pregnancy disorders, and preterm birth (PTB) and low birth weight (LBW)
Results
These disorders of pregnancy were associated with increased odds of PTB (AOR = 6.53; 95% CI: 4.33, 9.83) and LBW (AOR = 8.41; 95% CI: 4.16, 17.01). In the stratified analysis, the odds of both PTB and LBW decreased with increasing fruits and vegetables consumption. The interaction p values were 0.0006 and 0.3985 for PTB and LBW, respectively.
Conclusions
We found mother’s experience of GDM and HDP to be associated with PTB and LBW in this Ghanaian population and further provide evidence of the ameliorating role of fruits and vegetables consumption in the observed relationship. Mothers diagnosed of GDM and HDP should be advised during their antenatal visits to increase intake of fruits and vegetable consumption to help safeguard their health and that of the developing foetus.
Efficacy and safety of circular incision endoscopic mucosal resection and endoscopic mucosal dissection in the treatment of rectal neuroendocrine tumors：A Meta analysis
Authors: Yu Shangping , Wang Yan , Tian Miao , Qian Hongmei 
Published: May 2022

Abstract

Background: circular endoincision endoscopic mucosal resection (EMR-C) and endoscopic mucosal daresection (ESD) is two common methods in the resection of the turine rectal neuroendocrine tumors. Because there is no clear consensus on the best endoscopic resection technology, we conducted a meta-analysis to compare the effectiveness and safety of ESD and EMR-C in the treatment of rectal neuroendocrine tumors. Methods: Pubmed, EMBASE, Cochrane Library and Web of science were screened until November 2021. In the pairwise meta-analysis, according to the tumor size, 7 kinds of literature were divided into tumor size < 10mm group and tumor size 10-16mm group for subgroup analysis, and the heterogeneity between each group was analyzed.random effect and fixed-effect models were used for analysis, and sensitivity analysis and bias tests were also carried out. Results: seven studies involving 340 cases of rectal neuroendocrine tumors. For tumors, less than 10mm, the overall resection and complete resection rate of ESD are equivalent to that of EMR-C. The incidence of intraoperative bleeding and postoperative complications are not significantly different, but ESD will take more operation time than EMR-C. For 10-16mm tumors, the overall resection and complete resection rate of ESD are significantly higher than that of EMR-C. The incidences of intraoperative bleeding were not significantly different, but ESD took more operation time than EMR-C. Conclusion: This study shows that ESD is more effective in the treatment of rectal neuroendocrine tumors larger than 10mm because ESD has a deeper and higher mucosal resection rate. For tumors of less than 10mm, the results of EMR-C were equivalent to those of ESD
Risk factors of pelvic fracture combined with humeral fracture: A retrospective study
Authors: Li Zhengjiang , Chen Xing , Zhang Yan , Li Shunqiang , Ji Haibo , Li Yongkui , Xing Shuxing 
Published: May 2022

Abstract
Background: Pelvic fractures are often associated with other injuries, and in our study, pelvic fractures associated with humeral fractures were the most common. We pooled patient data to analyze the independent risk factors for pelvic fractures associated with humeral fractures. Methods: A retrospective study was conducted on the clinical data of 254 patients with pelvic fractures admitted to the Department of Orthopedics of Chengdu Fifth People’s Hospital, from August 2017 to August 2021. Independent sample T test found that pelvic fractures combined with humeral fractures were statistically significant. The main outcome indicators of pelvic fracture combined with humeral fracture were as follows: Tile classification of pelvic fractures, number of humeral fractures and Injury Severity Scale (ISS); Secondary outcome indicators: gender, age, body mass index (BMI), cause of injury, underlying diseases, etc. Single factor analysis was performed to screen risk factors for each indicator, and logistic analysis was used to determine independent risk factors for indicators with P < 0.05. Results: Of the 254 patients with pelvic fractures, 24 (9.45%) were associated with humeral fractures, much higher than other single injuries, and only pelvic fractures associated with humeral fractures were statistically significant (P=0.014). Pelvic fractures without concomitant humeral fractures (n=230) and pelvic fractures with concomitant humeral fractures (n=24) were associated with age (P=0.006; 95% CI = 0.087-0.665; OR=10.258), ISS score (P=0.002; 95% CI = 1.839-4.445; OR=8.721), Tile scores (P=0.01; 95% CI = 22.554-87.419; OR=22.736), but there was no statistical significance in gender (P=1.03), BMI (P=0.437) and injury cause (P=3.04). Conclusion: The combination of pelvic fracture and humerus fracture was statistically significant, and age > 60 years old, pelvic fracture Tile B2 classification above and high ISS were the independent risk factors for humerus fracture in pelvic fracture. Therefore, in clinical work, when clinicians treat patients with pelvic fractures aged > 60 years old, Tile B2 type above classification of pelvic fractures and high ISS, they should be highly vigilant about whether the humerus fractures are accompanied.
Gut microbiota composition can reflect immune responses and identify latent tuberculosis infection in patients with poorly controlled diabetes: A prospective cohort study
Authors: Huang Hung-Ling , Luo Yong-Chun , Lu Po-Liang , Huang Cheng-Hsieh , Lin Kun-Der , Lee Meng-Rui , Cheng Meng-Hsuan , Yeh Yao-Tsung , Kao Cheng-Yuan , Wang Jann-Yuan , Yang Jinn-Moon , Chong Inn-Wen 
Published: May 2022

Abstract
Background
Diabetes mellitus (DM) is a major risk factor for tuberculosis (TB). Evidence has linked the DM-related dysbiosis of gut microbiota to modifiable host immunity to Mycobacterium tuberculosis infection. However, the crosslinks between gut microbiota composition and immunological effects on the development of latent TB infection (LTBI) in DM patients remain uncertain.
Methods
We prospectively obtained stool, blood, and medical records from 130 patients with poorly-controlled DM (pDM), defined as ever having an HbA1c > 9.0% within previous 1 year. Among them, 43 had LTBI, as determined by QuantiFERON-TB Gold in-Tube assay. The differences in the taxonomic diversity of gut microbiota between LTBI and non-LTBI groups were investigated using 16S ribosomal RNA sequencing, and a predictive algorithm was established using a random forest model. Serum cytokine levels were measured to determine their correlations with gut microbiota.
Results
Compared with non-LTBI group, the microbiota in LTBI group displayed a similar alpha-diversity but different beta-diversity, featuring decrease of Prevotella_9, Streptococcus, and Actinomyces and increase of Bacteroides, Alistipes, and Blautia at the genus level. The accuracy was 0.872 for the LTBI prediction model using the aforementioned 6 microbiome-based biomarkers. Compared with the non-LTBI group, the LTBI group had a significantly lower serum levels of IL-17F (p = 0.025) and TNF-α (p = 0.038), which were correlated with the abundance of the aforementioned 6 taxa.
Conclusions
The study results suggest that gut microbiome composition may modulate host immunity relevant to TB susceptibility, and microbial signature might be a potential diagnostic biomarker and therapeutic target for LTBI in pDM patients.
Wideband Mimo Antenna with Reduced Mutual Coupling
Authors: Srinivasa P. 
Published: May 2022

Abstract
This work presents a revolutionary compact wideband multiple-input-multiple-output (MIMO) antenna. On the basis of the S-parameters and the surface current distributions, the working mechanism of the dual-antenna is investigated. The measured − 10dB impedance bandwidth is 6.8 GHz, and the measured mutual coupling is less than 15 dB throughout the whole band, according to a prototype. It is possible to attain a clearance area of 30 mm x 20 mm. To ensure the diversity performance of the proposed MIMO antenna, MIMO parameters such as ECC, DG, CCL, and multiplexing efficiency are explored.
Association of income level and ischemic heart disease: potential role of walkability
Authors: Cerci Rodrigo Julio , Fernandes-Silva Miguel Morita , Vitola João Vicente , Cerci Juliano Julio , Neto Carlos Cunha Pereira , Masukawa Margaret , Gracia Ana Paula Weller , Silvello Lara Luiza , Prado Pedro , Guedes Murilo , Hino Adriano Akira Ferreira , Baena Cristina Pellegrino 
Published: May 2022

Abstract
Background: Socioeconomic status has been linked to ischemic heart disease (IHD). High-income neighborhoods may expose individuals to a walking-promoting built environment for daily activities (walkability). Data from the association between income and IHD is lacking in middle-income countries (MIC). It is also uncertain whether walkability mediates this association. Objectives: To investigate whether: income is associated with IHD in a MIC; and whether neighborhood walkability mediates the income-IHD association. Methods: This cross-sectional study evaluated 44,589 patients referred for myocardial perfusion imaging (SPECT-MPI). Income and walkability were derived from participants’ residential census tract. Walkability quantitative score combined four variables: street connectivity, residential density, commercial density, and mixed land use. IHD was defined by an abnormal myocardial perfusion during a SPECT-MPI study. We used adjusted mixed effects models to evaluate the association between income level and IHD; and performed a mediation analysis to measure the percentage of the income-IHD association mediated by walkability. Results: From 26,415 participants, those living in the lowest income tertile census tract were more physically inactive (79.1 vs 75.8 vs 72.7%) when compared to higher income census tracts (p<0.001). Income was associated with IHD (OR 0.90 [95%CI 0.87 – 0.94] for each US$ 1,000.00 increase in income). Census tracts with higher income were associated with better walkability (p <0.001), however, walkability did not mediate the income-IHD association (percent mediated = -0.3%).Conclusions: Income was independently associated with higher prevalence of IHD in a MIC. Although walkability was associated with census tract income, it did not mediate the income-IHD association.
Automated oxygen control for very preterm infants and neurodevelopmental outcome at two years – a retrospective cohort study
Authors: Salverda H.H. , Oldenburger N.J. , Rijken M. , Tan R.N.G.B. , Pas A.B. Te , Klink J.M.M. van 
Published: May 2022

Abstract
Faster resolution of hypoxaemic or hyperoxaemic events in preterm infants may reduce long-term neurodevelopmental impairment. Automatic titration of inspiratory oxygen increases time within the oxygen saturation target range and may provide a more prompt response to hypoxic and hyperoxic events. We assessed routinely performed follow-up at two years of age after implementation of automated oxygen control (AOC) as standard care and compared this with a historical cohort. Neurodevelopmental outcomes at two years of age were compared for infants born at 24–29 weeks gestational age before (2012–2015) and after (2015–2018) implementation of AOC as standard of care. Primary outcome was a composite outcome of either mortality or severe neurodevelopmental impairment (NDI), other outcomes assessed were mild-moderate NDI, Bayley-III composite scores, cerebral palsy GMFCS and CBCL problem behaviour scores. 289 infants were eligible in the pre-AOC epoch and 292 in the post-AOC epoch. Baseline characteristics were not significantly different. 51 infants were lost to follow-up (pre-AOC 6.9% (20/289), post-implementation 10.6% (31/292)). The composite outcome of mortality or severe NDI was observed in 17.9% pre-AOC (41/229) vs. 24.0% (47/196) post-AOC (p = 0.12). No significant differences were found for the secondary outcomes such as mild-moderate NDI, Bayley-III composite scores, cerebral palsy GMFCS and problem behaviour scores, with the exception of parent-reported readmissions until moment of follow-up which was less frequent post-AOC than pre-AOC. Conclusion In this cohort study, Implementation of automated oxygen control in our NICU as standard of care for preterm infants led to no statistically significant difference in neurodevelopmental outcome at two years of age.
Predictors of urinary function recovery after radical prostatectomy
Authors: Hakozaki Kyohei , Takeda Toshikazu , Yasumizu Yota , Tanaka Nobuyuki , Matsumoto Kazuhiro , Morita Shinya , Kosaka Takeo , Mizuno Ryuichi , Asanuma Hiroshi , Oya Mototsugu 
Published: May 2022

Abstract
Purpose: Even in the era of laparoscopic radical prostatectomy (LRP) and robot-assisted laparoscopic radical prostatectomy (RALP), we sometimes experience patients with severe urinary incontinence after surgery. The aim of this study was to identify the predictors of urinary continence recovery among patients with urinary incontinence immediately after surgery (UIIAS).Methods: We identified 274 patients with clinically localized prostate cancer who underwent LRP and RALP between 2011 and 2018. UIIAS was defined as a urine loss ratio > 0.15 on the first day of urethral catheter removal. Urinary continence recovery was defined as using ≤ 1 pad/day one year after surgery. In the present study, we evaluated the factors affecting urinary function recovery one year after surgery among patients with urinary incontinence immediately after LRP and RALP.Results: UIIAS was observed in 191 of 274 patients (69.7%). A multivariate analysis identified age (< 65 years, p = 0.015) as an independent predictor affecting immediate urinary continence. Among the 191 incontinent patients, 153 patients (80.1%) showed improved urinary continence one year after surgery. A multivariate analysis identified age (< 65 years, p = 0.003) and estimated blood loss (≥ 100 ml, p = 0.044) as independent predictors affecting urinary continence recovery one year after surgery. Conclusions: The present results suggest that younger patients and patients with higher intraoperative blood loss might recover urinary continence one year after surgery even if they are incontinent immediately after surgery.
Shortcuts to adiabatic population inversion via time-rescaling: stability and thermodynamic cost
Authors: Andrade Jair da Silva , França Angelo F. da Silva , Bernardo Bertúlio de Lima 
Published: May 2022

Abstract
A shortcut to adiabaticity (STA) is concerned with the fast and robust manipulation of the dynamics of a quantum system that reproduces the effect of an adiabatic process. A recently proposed method enables the generation of shortcuts from a prescribed slow dynamics by simply rescaling the time variable of the quantum evolution operator. This time-rescaling method does not demand knowledge about the eigenvalues and eigenstates of the Hamiltonian, and in many cases no additional coupling fields. Here, we use this approach to study the problem of speeding up the population inversion of a two-level quantum system. The fidelity of the dynamics versus systematic errors in the control parameters are shown to be comparable with other STA schemes. From a quantum thermodynamic viewpoint, we also demonstrate that the main properties of the distribution of work required to drivethe system along the shortcuts are unchanged with respect to the reference (slow) protocol.PACS numbers:
Performance Evaluation of Combining ICESat-2 and GEDI Laser Altimetry Missions for Inland Lake Level Retrievals
Authors: Zhang Zhijie , Chen Guodong , Bo Yanchen , Guo Xiaozu , Bao Jianteng 
Published: May 2022

Abstract
Monitoring lake water levels is important to fully understand the characteristics and mechanism of lakes’ dynamic change, the impact of climate change and human activities on lakes, etc. This paper first individually evaluated the performance of newly released Global Ecosystem Dynamics Investigation (GEDI) and the successor of Ice, Cloud, and Land Elevation Satellite mission (ICESat-2) for inland lake level retrieval over four typical lakes (Chaohu Lake, Hongze Lake, Gaoyou Lake and Taihu Lake) using in-situ gauge data, then lake levels of the two missions were combined to derive long time-series lake water levels. Compared with in-situ water levels, the validations revealed that very accurate results were obtained by ICESat-2 with R varing from 0.957 to 0.995, MAE 0.03 m-0.10 m and RMSE 0.04 m-0.13 m, however, larger bias occurred in GEDI results with R spanning from 0.560 to 0.952, MAE 0.31 m-0.38 m and RMSE 0.35 m-0.46 m. Before combination, the bias correction of GEDI was carried out. The annual change rate differences between the combined and the in-situ data were 0.06 m/yr, 0.05 m/yr, 0.05 m/yr and 0.02 m/yr for Lake Chaohu, Hongze, Gaoyou and Taihu, respectively. The monthly, seasonal and annual dynamics of inland lake water levels captured by combined GEDI and ICESat-2 missions agree well with measuremnts from hydrological stations. These encouraging results demonstrate the great potential for frequent and accurate lake level monitoring, which could be a valuable resource for the studies of hydrological and climatic change.
Bioinformatic analysis of COL10A1 expression correlates with poor prognosis and immune infiltration in pancreatic cancer
Authors: Liu Qi , Zhao Hongyu , Guo Yu , Zhang Kai , Shang Fengjia , Liu Tongjun 
Published: May 2022

Abstract
Background
Collagen type X alpha 1 (COL10A1) is a structural component of the extracellular matrix that is aberrantly expressed in a variety of cancer tissues. However, its role in pancreatic cancer progression is not well understood.
Methods
TCGA, GEO, and GEPIA data were employed to explore the expression of COL10A1 in normal and tumor tissues and its prognostic value in pancreatic adenocarcinoma. The clinical data of pancreatic cancer in TCGA were used to explore the relationship between COL10A1 and clinical features. Genes co-expressed with COL10A1 were explored using multiple databases and analyzed for functional enrichment. In addition, the lncRNA-miRNA-COL10A1 axis that may be involved in COL10A1 regulation in pancreatic cancer was explored by constructing a competitive endogenous RNA (ceRNA) regulatory axis. Finally, COL10A1 was analyzed for correlation with immune cell infiltration and various immune checkpoint molecules in pancreatic cancer to explore the mechanisms that may affect prognosis.
Results
It was found that the expression of COL10A1 was significantly increased in pancreatic cancer tissues. High expression of COL10A1 was related to the clinicopathological characteristics and the worse prognosis of pancreatic cancer patients. The role of COL10A1 in promoting pancreatic cancer progression may be mediated by the TUG1/miR-144-3p/COL10A1 axis. Besides, in pancreatic adenocarcinoma, the expression level of COL10A1 showed a significant positive correlation with tumor immune cell infiltration, biomarkers of immune cells, and expression of immune checkpoint molecules.
Conclusion
In this article, with the help of many bioinformatics techniques, we conclude that TUG1/miR-144-3p/COL10A1 axis is associated with immune infiltration of pancreatic cancer and leads to poor prognosis. COL10A1 is an early diagnostic marker and a potential therapeutic target for pancreatic cancer.