bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative spectroscopic investigation of Dy3+ ions in different sesquioxide solid solution ceramics
Authors: Wang Wei , Jiang Benxue , Feng Tao , Fan Jintai , Zhang Long 
Published: April 2022

AbstractA comparative study of the spectroscopic properties of LuScO3:Dy, LuYO3:Dy, and YScO3:Dy was conducted to evaluate their application prospects in yellow laser generation. The absorption cross sections of Dy‐doped LuScO3, LuYO3, and YScO3 at 446 nm were calculated to be 0.67, 1.51, and 1.05 × 10−21 cm2, respectively. The Judd–Ofelt (J–O) theory was used to determine the J–O parameters as well as the spontaneous transition probability and fluorescence branching ratios. The fluorescence spectra of LuScO3:Dy, LuYO3:Dy, and YScO3:Dy were dominated by yellow emission corresponding to the 4F9/2 → 6H13/2 transition, with cross sections of 0.78, 1.10, and 0.76 × 10−20 cm2, respectively. The Inokuti–Hirayama model was applied to fit the non‐exponential decay curve of Dy‐doped sesquioxide solid solution ceramics in order to investigate the process of energy transfer. The impact of bond length and distortion degree on spectral properties and energy‐transfer parameters was investigated. It was concluded that among Dy‐doped sesquioxide solid solutions, LuYO3:Dy ceramics are the most promising materials for generating yellow lasers.
Lipid droplets and autophagosomes together with chaperones fine‐tune expression of SGK1
Authors: Ghani Madiha J. , Gu Wenxue , Chen Zhuyuan , Canessa Cecilia M. 
Published: April 2022

AbstractSerum‐glucocorticoid‐induced kinase‐1 (SGK1) regulates ion homeostasis and promotes survival under stress conditions. The expression of SGK1 is under transcriptional and post‐translational regulations that are frequently altered in cancer and immune disorders. We report that an N‐terminal amphipathic alpha‐helix determines SGK1 expression levels through two distinct mechanisms. It tethers SGK1 to intracellular organelles generating a large pool of membrane‐bound SGK1, which is differentially stabilized in lipid droplets (LD) in fed conditions or degraded in the endoplasmic reticulum by ER‐phagy in starvation. Association of the α‐helix to organelles does not depend on dedicated receptors or special phospholipids rather, it is intrinsic to its physicochemical properties and depends on the presence of bulky hydrophobic residues for attachment to LDs. The second mechanism is recruitment of protein‐chaperones that recognize the α‐helix as an unfolded protein promoting survival of the cytosolic SGK1 fraction. Together, the findings unveil an unexpected link between levels of energy storage and abundance of SGK1 and how changes in calorie intake could be used to modulate SGK1 expression, whereas the inhibition of molecular chaperones could serve as an additional enhancer in the treatment of malignancies and autoimmune disorders with high levels of SGK1 expression.
Glutathione regulates transcriptional activation of iron transporters via S‐nitrosylation of bHLH factors to modulate subcellular iron homoeostasis
Authors: Shee Ranjana , Ghosh Soumi , Khan Pinki , Sahid Salman , Roy Chandan , Shee Dibyendu , Paul Soumitra , Datta Riddhi 
Published: April 2022

AbstractGlutathione (GSH) is known to regulate iron (Fe) deficiency response in plants but its involvement in modulating subcellular Fe homoeostasis remains elusive. In this study, we report that the GSH‐deficient mutants, cad2‐1 and pad2‐1 displayed increased sensitivity to Fe deficiency with significant downregulation of the vacuolar Fe exporters, AtNRAMP3 and AtNRAMP4, and the chloroplast Fe importer, AtPIC1. Moreover, the pad2‐1 mutant accumulated higher Fe levels in vacuoles but lower Fe levels in chloroplasts compared to wild type (Columbia ecotype [Col‐0]) under Fe limited conditions. Exogenous GSH treatment enhanced chloroplast Fe contents in Col‐0 but failed to do so in the nramp3nramp4 double mutants demonstrating that GSH plays a role in modulating subcellular Fe homoeostasis. Pharmacological experiments, mutant analysis, and promoter assays revealed that this regulation involves the transcriptional activation of Fe transporter genes by a GSH–S‐nitrosoglutathione (GSNO) module. The Fe responsive bHLH transcription factors (TFs), AtbHLH29, AtbHLH38, and AtbHLH101 were found to interact with the promoters of these genes, which were, in turn, activated via S‐nitrosylation (SNO). Taken together, the present study highlights the role of the GSH–GSNO module in regulating subcellular Fe homoeostasis by transcriptional activation of the Fe transporters AtNRAMP3, AtNRAMP4, and AtPIC1 via SNO of bHLH TFs during Fe deficiency.
Processual Recognition in Chinese Traffic Disputes
Authors: Sangren Kristin M. 
Published: April 2022

AbstractThis article analyzes traffic dispute resolution in contemporary urban China as embodying what I term processual recognition. I describe how various complex status‐inflected qualities, legal‐bureaucratic institutions and actors, and processes and perceptions of recognition interact in producing resolutions and a sense of (in)justice or (un)fairness. My attention to “recognition” is distinctive in foregrounding disputants’ investments in identity and dignity as enacted through embodied and affective practices. Contrary to accounts of contemporary China that emphasize moral breakdown, I argue that traffic disputes between strangers produce a spatially and temporally contingent moral economy that connects the production of justice with individual desire for recognition, socio‐structural configurations, and legal‐bureaucratic imperatives. I further argue that existing accounts focused on substantive and procedural justice fail to accommodate variant cultural and institutional configurations of dispute resolution, and that scholars should also attend to questions of recognition.
A Principal Stratification Approach to Estimating the Effect of Continuing Treatment after Observing Early Outcomes
Authors: Schnell Patrick M. , Baumgartner Richard , Mt-Isa Shahrul , Svetnik Vladimir 
Published: April 2022

AbstractChronic diseases often require continuing care, and early response to treatment can be an important predictor of long-term efficacy. Often, an apparent lack of early efficacy may lead to discontinuation of treatment, with the decision made either by clinicians or by the patients themselves. Thus, it is important to determine whether or not a desired early outcome corresponds to a beneficial long-term effect of continuing treatment, and conversely, whether or not the absence of such an outcome corresponds to a lack of long-term benefit. However, primary clinical trials of such treatments are not commonly designed to answer such questions, for example by randomizing subjects to continue or discontinue treatment after observing early outcomes. We propose an approach to estimating the effect of continuing treatment after observing early outcomes using data from randomized controlled trials in which treatment discontinuation was not part of the design. Our approach estimates average causal effects of continuing treatment on long-term outcomes in principal strata defined by the potential early outcomes under treatment. For illustration, we estimate the effects of continuing to take gaboxadol to treat insomnia conditional on early improvement in subjective sleep quality after two nights, based on a standard parallel-arm randomized controlled trial.
Effect of microstructural variation on strain localization in double‐sided friction stir welded AA6061‐AA7075 joints
Authors: Garg Ashu , Bhattacharya Anirban 
Published: April 2022

AbstractIn friction stir welding (FSW), the inhomogeneous microstructure significantly affects the mechanical performance of the joints. The present study investigates the influence of microstructural asymmetry along the thickness on strain localization during tensile test using the digital image correlation technique and fracture morphology for double‐sided FSW (DS‐FSW) AA6061‐AA7075 joints. In top and bottom slices of the transverse tensile sample, nonhomogenous strain localization is noted in heat affected zone (HAZ) of the advancing side (AS), that is, AA6061‐T6, and also presents higher tensile strength. However, in the middle slice of the transverse sample, larger region including thermo‐mechanically affected zone and HAZ undergoes strain localization and exhibits higher elongation at failure. In longitudinal specimens, the strain distribution is homogeneous up to uniform elongation followed by strain concentration at a localised region and fracture. Electron backscatter diffraction revealed that the extent of dynamic recrystallization on the retreating side (AA7075‐T61) is higher than that observed on the AS of the weld. The grain orientation spread map showed a high fraction of recrystallized grains at the weld centre. Presence of major shear textures components
and
both below the tool shoulder and weld centre regions are observed from pole figures. The recrystallized texture components P ({011}<112>), Goss ({110}<001>), Rotated Goss ({110}<110>), Cube ({001}<100>) and shear texture ({001}<110>) components is also noted at the weld centre. Middle slice both for longitudinal and transverse sample showed the finest dimple size on the fracture surfaces. The strain localization behaviour and tensile performance assessed for transverse and longitudinal samples can be helpful to find the load orientation dependency and safe design of DS‐FSW joints.
Combinatorial Effects of Clay-Type Silicate and MgO on Friction Braking Performance of Hybrid Phenolic Composites
Authors: Saha Debarghya , Satapathy Bhabani K. 
Published: April 2022

Abstract
Halloysite (tubular), montmorillonite (platy), and wollastonite (acicular) type clay silicate morphologies-based magnesium oxide (MgO) filled compression-molded hybrid friction composites were fabricated followed by their mechanical (compressive), thermal (onset of degradation), thermo-mechanical (loss modulus), and tribological performance (CoF, fade, recovery, wear) evaluation. The friction-fade and friction-recovery due to braking-induced heating and cooling cycles vis-a-vis the instantaneous braking performances were evaluated following SAEJ661, on a chase-type friction tester. The combination of halloysite–MgO in the friction composite led to minimum fade (∼2.2%), whereas that of wollastonite–MgO showed a maximum friction coefficient (∼0.47) with enhanced rotor friendliness as indicated from optical surface profilometry. Montmorillonite–MgO-based composites showed a maximum wear resistance along with a greater extent of friction stabilization as supported by ID/IG data from Raman spectra. The performance attributes remained governed by the compressive stiffness of the friction composites, hardness, thermal stability, and morphological aspects of the clay-type silicates, and their induced contact dynamics as evident from scanning electron microscopy–energy-dispersive X-ray spectroscopy (SEM–EDX) studies. The heat dissipation mechanism, the disc temperature rise, and friction coefficient under instantaneous braking condition were found to be controlled by MgO in the composites. The study demonstrates that clay-type silicate morphologies in combination with MgO as a mild abrasive may lead to synergistic fade–recovery performance without compromising the compressive stiffness response of the braking surface, enabling increased wear resistance.
Development of a Novel Approach to Predict Tool Life Based on Tool Path Features in Ta6V Milling
Authors: Lagarde Q. , Wagner V. , Dessein G. , Couderc P. 
Published: April 2022

Abstract
In the manufacturing industry, titanium alloys machining has always been a challenge, mostly because of tool premature wear. Consequently, the understanding of physical phenomena and their modeling have become critical research topics for productivity improvement. The majority of tool wear model is based on cutting condition variations. However, several tool paths with the same cutting conditions lead to different tool lives. The impact of the cutting strategy is significant on tool wear and complex to anticipate. In this article, a global method allowing to estimate the impact of a cutting strategy on tool life is presented. It is based on tool path features extracted from workshop cutting power signals collection. First, optimal cutting conditions are determined according to AFNOR standard by minimizing specific cutting coefficient. Then, correlation analysis is carried out for different configurations of the database. Special iconography of correlations is used to explain links between the features. To finish, from the correlations between impact of the tool path on tool life and the features, a multiple regression model based on the method of least squares is computed to estimate the impact of the tool path on tool life. Physical correlations have been highlighted and confirmed the significant role of the cutting strategy on tool life. Models are quite accurate despite the low amount of data and the method is promising for an industrial implementation.
Ligurian hyperextended continental margin preserved in an ophiolitic block at Timpa di Pietrasasso, Calabrian Arc, southern Italy
Authors: Shimabukuro David H. , Battistella Claire 
Published: April 2022

ABSTRACT
The Cenozoic accretionary complex in the Calabrian Arc, southern Italy, contains hectometric- to kilometric-scale exposures of basalt, gabbro, and serpentinite that have been interpreted as dismembered fragments of Alpine Tethys ocean crust because of their incomplete nature with respect to the traditional view of a complete ophiolite sequence. We present new geologic mapping, geochemistry, and geochronology of one of these units at Timpa di Pietrasasso near the town of Terranova di Pollino in the Basilicata region that exposes Jurassic Tethyan pillow basalt and chert that are separated from gabbro and serpentinite by a fault. The gabbro in the footwall is Permian in age, indicated by U-Pb zircon ages of 284 ± 6 Ma, 293 ± 6 Ma, and 295 ± 4 Ma, linking it to gabbros that underplated continental crust after the Permo-Carboniferous Variscan Orogeny. The gabbro first underwent amphibolite-facies metamorphism, then developed a greenschist-facies mylonitic foliation near the fault surface that is crosscut by undeformed Jurassic-aged dikes of Tethyan origin, indicating that deformation is early Tethyan or pre-Tethyan in age. The underlying serpentinite is tectonically interleaved with blocks of Variscan lower crust, indicating that the missing upper plate of the extensional detachment complex was continental in origin. These features indicate that the Timpa di Pietrasasso unit preserves a low-angle detachment fault that developed in a hyperextended continental margin of the Alpine Tethys.
High-resolution record of multiple organic carbon-isotope excursions in lacustrine deposits of Upper Sinemurian through Pliensbachian (Early Jurassic) from the Sichuan Basin, China
Authors: Franceschi Marco , Jin Xin , Shi Zhiqiang , Chen Bin , Preto Nereo , Roghi Guido , Corso Jacopo Dal , Han Lu 
Published: April 2022

Abstract
The Sinemurian-Pliensbachian boundary event (ca. 193 Ma) is recorded as a global perturbation of the carbon cycle, as evidenced by a large negative carbon-isotope excursion recorded in many marine sedimentary successions. Whereas multiple lines of evidence testify that the Sinemurian-Pliensbachian boundary event was associated with environmental and climatic changes, sea-level oscillations, and biotic turnovers in marine settings, the record and effects of the event on continents are poorly known. In this paper, we report a high-resolution δ13Corg record and palynological data from the Lower Jurassic lacustrine succession of the Sichuan Basin that allow a prominent 8‰ negative carbon-isotope excursion to be identified at the Sinemurian-Pliensbachian transition. We therefore interpret this perturbation as the expression of the Sinemurian-Pliensbachian boundary event in the Sichuan Basin, and we propose a correlation with the marine realm. Facies evolution illustrates that the Sinemurian-Pliensbachian boundary event coincided with a phase of expansion of the lacustrine systems. Palynological analyses indicate a sharp shift from arid to humid climate conditions coincident with the carbon-isotope perturbation that supports a scenario of lake expansion driven by increased rainfall. In contrast to observations in the Sichuan Basin, where deep lake conditions persisted across the Sinemurian-Pliensbachian boundary event, a global drop in the sea level is documented at the onset of the isotope perturbation. This suggests that eustatic oscillations due to increased continental water storage in lakes and aquifers in the context of a wetter climate phase may have been associated with the early stages of the Sinemurian-Pliensbachian boundary event.
The Afghan Events of 1979–1989: From Knowledge to Understanding and Recognition
Authors: Khristoforov V. S. 
Published: April 2022

Abstract
The circumstances that led to the entry of Soviet troops into Afghanistan are analyzed, and the international and domestic political situation in Afghanistan after the coup d’état and the announcement by the new authorities of the course towards building socialism, as well as contradictions between the People’s Democratic Party of Afghanistan (PDPA) factions, are examined. The development of the combat actions of the Soviet troops is studied, and the difficulties that the military had to face in the conditions of resistance from a significant part of the country’s population are considered. The support of the actions of the troops by official Soviet propaganda, including hushing up real losses, is considered in detail. Of considerable interest are data on an ideological confrontation: attempts by the Western allies of the Mujahideen to influence the Soviet military contingent.
Single use versus reusable catheters in intermittent catheterisation for treatment of urinary retention: a protocol for a multicentre, prospective, randomised controlled, non-inferiority trial (COMPaRE)
Authors: van Doorn Tess , Berendsen Sophie A , Scheepe Jeroen R , Blok Bertil F M 
Published: April 2022

IntroductionChronic urinary retention is a common lower urinary tract disorder, mostly neurogenic or idiopathic in origin. The preferred treatment is clean intermittent urinary self-catheterisation (CISC) four to six times a day. In most European countries, virtually all patients use single use catheters, which is in contrast to several countries where the use of reusable catheters is more common. The available literature on the use of reusable catheters is conflicting and until now, no randomised controlled trial with sufficient power has been performed to investigate if reusable catheters for CISC is as safe as single use catheters.Methods and analysisWe described this protocol for a prospective, randomised controlled non-inferiority trial to investigate if the use of reusable catheters is as safe as single use catheters for CISC patients, measured by symptomatic urinary tract infections (sUTIs). Secondary objectives are adverse events due to a sUTI, urethral damage, stone formation, quality of life and patient satisfaction. A cost-effectiveness analysis will also be performed. 456 Participants will be randomised into two groups stratified for age, gender, menopausal status and (non-)neurogenic underlying disorder. The intervention group will replace the reusable catheter set every 2 weeks for a new set and replace the cleaning solution every 24 hours. The control group continues to use its own catheters. The primary outcome (amount of sUTIs from baseline to 1 year) will be tested for non-inferiority. Categorical outcome measures will be analysed using χ2 tests and quantitative outcome variables by t-tests or Mann-Whitney U tests. Two-sided p values will be calculated.Ethics and disseminationThis protocol was reviewed and approved by the Medical Ethics Committee of the Erasmus MC (MEC 2019-0134) and will be performed according to the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) checklist for non-inferiority trials. The results of this randomised controlled non-inferiority trial will be published in a peer-reviewed journal and will be publicly available.Trial registration numberNL8296.
Non-pharmacological therapies for postviral syndromes, including Long COVID: a systematic review and meta-analysis protocol
Authors: Chandan Joht Singh , Brown Kirsty , Simms-Williams Nikita , Camaradou Jenny , Bashir Nasir , Heining Dominic , Aiyegbusi Olalekan Lee , Turner Grace , Cruz Rivera Samantha , Hotham Richard , Nirantharakumar Krishnarajah , Sivan Manoj , Khunti Kamlesh , Raindi Devan , Marwaha Steven , Hughes Sarah E , McMullan Christel , Calvert Melanie , Haroon Shamil 
Published: April 2022

IntroductionPostviral syndromes (PVS) describe the sustained presence of symptoms following an acute viral infection, for months or even years. Exposure to the SARS-CoV-2 virus and subsequent development of COVID-19 has shown to have similar effects with individuals continuing to exhibit symptoms for greater than 12 weeks. The sustained presence of symptoms is variably referred to as ‘post COVID-19 syndrome’, ‘post-COVID condition’ or more commonly ‘Long COVID’. Knowledge of the long-term health impacts and treatments for Long COVID are evolving. To minimise overlap with existing work in the field exploring treatments of Long COVID, we have only chosen to focus on non-pharmacological treatments.AimsThis review aims to summarise the effectiveness of non-pharmacological treatments for PVS, including Long COVID. A secondary aim is to summarise the symptoms and health impacts associated with PVS in individuals recruited to treatment studies.Methods and analysisPrimary electronic searches will be performed in bibliographic databases including: Embase, MEDLINE, PyscINFO, CINAHL and MedRxiv from 1 January 2001 to 29 October 2021. At least two independent reviewers will screen each study for inclusion and data will be extracted from all eligible studies onto a data extraction form. The quality of all included studies will be assessed using Cochrane risk of bias tools and the Newcastle-Ottawa grading system. Non-pharmacological treatments for PVS and Long COVID will be narratively summarised and effect estimates will be pooled using random effects meta-analysis where there is sufficient methodological homogeneity. The symptoms and health impacts reported in the included studies on non-pharmacological interventions will be extracted and narratively reported.Ethics and disseminationThis systematic review does not require ethical approval. The findings from this study will be submitted for peer-reviewed publication, shared at conference presentations and disseminated to both clinical and patient groups.PROSPERO registration numberThe review will adhere to this protocol which has also been registered with PROSPERO (CRD42021282074).