bluuebunny/crossref_metadata_2025_split huggingface dataset:
Results of the North American Complex Abdominal Aortic Debranching (NACAAD) Registry
Authors: Escobar Guillermo A. , Oderich Gustavo S. , Farber Mark A. , de Souza Leonardo R. , Quinones-Baldrich William J. , Patel Himanshu J. , Eliason Jonathan L. , Upchurch Gilbert R. , H. Timaran Carlos , Black James H. , Ellozy Sharif H. , Woo Edward Y. , Fillinger Mark F. , Singh Michael J. , Lee Jason T. , C. Jimenez Juan , Lall Purandath , Gloviczki Peter , Kalra Manju , Duncan Audra A. , Lyden Sean P. , Tenorio Emanuel R. ,   for the NACAAD Investigators
Published: October 2022

Background:
Hybrid debranching repair of pararenal and thoracoabdominal aortic aneurysms was initially designed as a better alternative to standard open repair, addressing the limitations of endovascular repair involving the visceral aorta. We reviewed the collective outcomes of hybrid debranching repairs using extra-anatomic, open surgical debranching of the renal-mesenteric arteries, followed by endovascular aortic stenting.

Methods:
Data from patients who underwent hybrid repair in 14 North American institutions during 10 years were retrospectively reviewed. Society of Vascular Surgery scores were used to assess comorbidity risk. Early and late outcomes, including mortality, morbidity, reintervention, and patency were analyzed.

Results:

A total of 208 patients (118 male; mean age, 71±8 years old) were treated by hybrid repair with extraanatomic reconstruction of 657 renal and mesenteric arteries (mean 3.2 vessels/patient). Mean aneurysm diameter was 6.6±1.3 cm. Thoracoabdominal aortic aneurysms were identified in 163 (78%) patients and pararenal aneurysms in 45 (22%). A single-stage repair was performed in 92 (44%) patients. The iliac arteries were the most common source of inflow (n=132; 63%), and most (n=150; 72%) had 3 or more bypasses. There were 30 (14%) early deaths, ranging widely across sites (0%–21%). A Society of Vascular Surgery comorbidity score >15 was the primary predictor of early mortality (
P
<0.01), whereas mortality was 3% in a score ≤9. Early complications occurred in 140 (73%) patients and included respiratory complications in 45 patients (22%) and spinal cord ischemia in 22 (11%), of whom 10 (45%) fully recovered. At 5 years, survival was 61±5%, primary graft patency was 90±2%, and secondary patency was 93±2%. The most significant predictor of late mortality was renal insufficiency (
P
<0.0001).

Conclusions:
Mortality after hybrid repair and visceral debranching is highly variable by center, but strongly affected by preoperative comorbidities and the centers’ experience with the technique. With excellent graft patency at 5 years, the outcomes of hybrid repair done at centers of excellence and in carefully selected patients may be comparable (or better) than traditional open or even totally endovascular approaches. However, in patients already considered as high-risk for surgery, it may not offer better outcomes.
The Diabatic Rossby Vortex: Growth Rate, Length Scale, and the Wave–Vortex Transition
Authors: Kohl Matthieu , O’Gorman Paul A. 
Published: October 2022

Abstract
In idealized simulations of moist baroclinic instability on a sphere, the most unstable mode transitions from a periodic wave to an isolated vortex in sufficiently warm climates. The vortex mode is maintained through latent heating and shows the principal characteristics of a diabatic Rossby vortex (DRV) that has been found in a range of different simulations and observations of the current climate. Currently, there is no analytical theory for DRVs or understanding of the wave–vortex transition that has been found in warmer climates. Here, we introduce a minimal moist two-layer quasigeostrophic model with tilted boundaries capable of producing a DRV mode, and we derive growth rates and length scales for this DRV mode. In the limit of a convectively neutral stratification, the length scale of ascent of the DRV is the same as that of a periodic moist baroclinic wave, but the growth rate of the DRV is 54% faster. We explain the isolated structure of the DRV using a simple potential vorticity (PV) argument, and we create a phase diagram for when the most unstable solution is a periodic wave versus a DRV, with the DRV emerging when the moist static stability and meridional PV gradients are weak. Last, we compare the structure of the DRV mode with DRV storms found in reanalysis and with a DRV storm in a warm-climate simulation.

Significance Statement
Past research has identified a special class of midlatitude storm, dubbed the diabatic Rossby vortex (DRV), which derives its energy from the release of latent heat associated with condensation of water vapor and as such goes beyond the traditional understanding of midlatitude storm formation. DRVs have been implicated in extreme and poorly predicted forms of cyclogenesis along the east coast of the United States and the west coast of Europe with significant damage to property and human life. The purpose of this study is to develop a mathematical theory for the intensification rate and length scale of DRVs to gain a deeper understanding of the dynamics of these storms in current and future climates.
A Meta-Analytic Review of Social Learning Theory and Teen Dating Violence Perpetration
Authors: Pusch Natasha 
Published: October 2022

Objectives The purpose of this study is to examine social learning theory (SLT) and teen dating violence (TDV) perpetration. This study aims to determine which predictors have the largest effect sizes, whether they vary for males and females, and whether they differ based on research design and sample characteristics. Methods This study uses hierarchal meta-analytic methods to examine both within- and between-dataset differences in relationships between a variety of SLT predictors and TDV outcomes. Both bivariate and multivariate effect sizes are computed for a sample of n = 1,157 effect sizes nested in n = 116 studies that used n = 88 unique datasets. Results Findings indicate that a variety of SLT predictors can explain TDV perpetration. Predictors with the largest effect sizes include anticipated benefits of TDV (Bivariate: r = .254; multivariate: r = .308) and peer TDV perpetration (Bivariate: r = .279; multivariate: r = .205). While most predictors show similar effect sizes for males and females, peer TDV perpetration appears to be a stronger influence for males. Several significant moderators are found. Conclusions SLT should continue to provide a theoretical framework for TDV research and practice. Future research should examine same-sex teen relationships and sexual minorities.
The protective mechanism of salidroside modulating miR-199a-5p/TNFAIP8L2 on lipopolysaccharide-induced MLE-12 cells
Authors: Tan Yang , Zou Yong-fan , Zhang Huang-bo , Liu Xu , Qian Chuan-yun , Liu Ming-Wei 
Published: October 2022

Objectives Salidroside is used for treating inflammation-based diseases; however, its molecular mechanism is unclear. In this study, we determined the protective role of salidroside on the endotoxin-induced damage caused to the mouse alveolar epithelial type II (MLE-12) cells and its underlying mechanism. Methods An in vitro model for acute lung injury was constructed by inducing the MLE-12 cells using lipopolysaccharide (lipopolysaccharides, 1 mg/L). Then, The MTT assay was conducted to assess the survival rate of the MLE-12 cells in the different groups. After the treatment, apoptosis of MLE-12 cells was determined, and the mRNA and protein expression of miR-199a-5p, HMGB1, NF-kB65, TNFAIP8L2, p-IkB-α, and TLR4 was estimated by Western Blotting and RT-PCR. ELISA was also used to measure the concentration of inflammatory cytokine molecules IL-1β, IL-6, TNF-α, and IL-18 in the cell-free supernatant. Lastly, cell morphology was examined using the AO/EB technique. Results We showed that salidroside reduced the protein and gene expression of HMGB1, NF-kB65, miR-199a-5p, p-IkB-α, and TLR4, whereas it increased the gene and protein expression of TNFAIP8L2. Furthermore, it decreased the concentrations of cytokine molecules like IL-1β, IL-6, TNF-α, and IL-18 in the cell-free supernatant. MLE-12 also showed a lower apoptosis rate, higher survival rate, and better cell morphology. Conclusion Salidroside significantly inhibited the LPS-induced MLE-12 cell damage. Our results suggest that this could be by reducing miR-199a-5p and enhancing TNFAIP8L2 expression.
The Understanding of Maternal Smoking among Women who were Smoking or had Quit Smoking during Pregnancy
Authors: Small Sandra , Brennan-Hunter Andrea , Yi Yanqing , Porr Caroline 
Published: October 2022

Background Maternal tobacco smoking during pregnancy is associated with adverse health effects for the woman, fetus, and child, including such serious effects as preterm birth, low birth weight, stillbirth, and neonatal and sudden infant death. Smoking cessation during pregnancy reduces health risks. Purpose In order to support pregnant women to quit smoking, it is essential to know determinants of quitting smoking in pregnancy. The purpose of this research was to examine women's understanding of maternal smoking, in terms of their beliefs, in relation to quitting smoking during pregnancy. Methods The study was a cross-sectional survey with anonymous questionnaires. The sample consisted of 161 pregnant and postnatal women who were continuing or had continued to smoke during pregnancy or had quit smoking during pregnancy. Logistic regression was used to determine the impact of women's understanding of maternal smoking on quitting smoking in pregnancy. Results A large majority of the women had low to moderate understanding of maternal smoking. Those with higher levels of understanding were more likely to quit smoking during pregnancy than were those with a low level of understanding. Not having children prior to the current pregnancy or childbirth also increased the likelihood of quitting smoking during pregnancy while being without a partner combined with having a longer duration of smoking decreased the likelihood of quitting smoking during pregnancy. Conclusion As a modifiable factor, pregnant women's understanding of maternal smoking can be readily targeted with informational interventions in an effort to help them quit smoking.
Assessment of Admission COVID-19 Associated Hyperinflammation Syndrome Score in Critically-Ill COVID-19 Patients
Authors: Yildirim Mehmet , Halacli Burcin , Yuce Deniz , Gunegul Yunus , Ersoy Ebru Ortac , Topeli Arzu 
Published: October 2022

Purpose We aimed to evaluate the relation between admission COVID-19 associated hyperinflammatory syndrome (cHIS) score and intensive care unit (ICU) outcomes. Materials and Methods Patients with laboratory confirmed COVID-19 admitted to our ICU between 20th March 2020-15th June 2021 were included. Patients who received immunomodulatory treatment except corticosteroids were excluded. Main outcomes were ICU mortality and invasive mechanical ventilation (IMV) requirement after ICU admission. Results Three hundred and seventy patients with a median (IQR) age of 66 (56-77) were analyzed. Median admission cHIS score was 3 (2-4). A cHIS score ≥3 was found to be associated with ICU mortality (sensitivity = 0.63, specificity = 0.50; p < 0.01) and IMV requirement after ICU admission (sensitivity = 0.61, specificity = 0.51; p < 0.01). Patients with an admission cHIS score ≥3 (n = 199) had worse median admission APACHEII, SOFA scores and PaO2/FiO2 ratio than others (n = 171) (p < 0.01). IMV requirement after ICU admission (38.5% vs 26.1%;p = 0.03), ICU (36.2% vs 25.1%;p = 0.02), hospital (39.1% vs 26.9%;p = 0.01) and 28th day (28.1% vs 19.1%;p = 0.04) mortality were higher in patients with admission cHIS score ≥3 than others (p < 0.01). Age <65 years, malignancy and higher admission SOFA score were independent variables associated with admission cHIS score ≥3. Conclusion Critically-ill COVID-19 patients with admission cHIS score ≥3 have worse disease severity and outcomes than other patients.
How Media Literacy, Trust of Experts and Flu Vaccine Behaviors Associated with COVID-19 Vaccine Intentions
Authors: Austin Erica W. , Austin Bruce W. , Borah Porismita , Domgaard Shawn , McPherson Sterling M. 
Published: October 2022

Purpose To assess how previous experiences and new information contributed to COVID-19 vaccine intentions. Design Online survey (N = 1264) with quality checks. Setting Cross-sectional U.S. survey fielded June 22-July 18, 2020. Sample U.S. residents 18+; quotas reflecting U.S. Census, limited to English speakers participating in internet panels. Measures Media literacy for news content and sources, COVID-19 knowledge; perceived usefulness of health experts; if received flu vaccine in past 12 months; vaccine willingness scale; demographics. Analysis Structural equation modelling. Results Perceived usefulness of health experts ( b = .422, P < .001) and media literacy ( b = .162, P < .003) predicted most variance in vaccine intentions (R-squared=31.5%). A significant interaction ( b = .163, P < .001) between knowledge ( b = −.132, P = .052) and getting flu shot ( b = .185, P < .001) predicted additional 3.5% of the variance in future vaccine intentions. An increase in knowledge of COVID-19 associated with a decrease in vaccine intention among those declining the flu shot. Conclusion The interaction result suggests COVID-19 knowledge had a positive association with vaccine intention for flu shot recipients but a counter-productive association for those declining it. Media literacy and trust in health experts provided strong counterbalancing influences. Survey-based findings are correlational; thus, predictions are based on theory. Future research should study these relationships with panel data or experimental designs.
Psychometric Assessment of the Breastfeeding Self-Efficacy Scale-Short Form: A Confirmatory Factor Analysis in Malawian Mothers
Authors: Chipojola Roselyn , Dennis Cindy-Lee , Kuo Shu-Yu 
Published: October 2022

Background: Exclusive breastfeeding to 6 months postpartum has been related to breastfeeding self-efficacy in diverse populations. Globally, this is measured using the Breastfeeding Self-Efficacy Scale–Short Form (BSES-SF). Research Aim: To evaluate the psychometric properties of the BSES-SF among women in Malawi; and to examine the relationship between breastfeeding self-efficacy and demographic and health factors. Methods: The study design was a prospective, cross-sectional survey with a 2 week follow-up reliability check. Postpartum women ( N = 180) were recruited at a maternity hospital in Lilongwe, Malawi. In addition to the BSES-SF, the World Health Organization's Quality of Life Scale (QoL) was also administered. Furthermore, confirmatory factor analysis, Cronbach's alpha, and Pearson's correlations were used to examine the construct validity, reliability, test-retest reliability, and convergent validity. Results: The confirmatory factor analysis supported a unidimensional structure of the Malawian version of the 12-item BSES-SF. Cronbach's alpha and the intra-class correlation coefficient were 0.79 and 0.75, respectively. BSES-SF scores had significant correlation with QoL domains (physical QoL: r = 0.31, p < .001; and environmental QoL: r = 0.22, p < .01). Participants’ age, parity, and mode of delivery were positively correlated with breastfeeding self-efficacy scores. Conclusion: The findings of our study confirmed that the 12-item BSES-SF is a reliable and valid scale for assessing women’s breastfeeding self-efficacy in Malawi.
Outcomes and experiences of using oral voriconazole with or without concomitant topical agents to treat refractory vulvovaginal yeast infections
Authors: Morris Georgina Claire , Dean Gillian , Soni Suneeta , Sundaram Sangeetha , Fearnley Nicola , Wilson Janet Diane 
Published: October 2022

Background We describe 11 cases of refractory vulvovaginal yeast infections (RVVYI) treated using oral voriconazole with or without concomitant topical agents. Methods Retrospective case-note review of all women prescribed oral voriconazole to treat RVVYI in five Sexual Health Clinics from Jan 2010-March 2020. Demographic details, clinical features, diagnostic results and treatment outcomes were collected. Results 11 women with vulvovaginal symptoms for a median of 1 year were treated with voriconazole. RVVYI was diagnosed clinically and confirmed on microscopy and culture with speciation. 10/11 isolates were fluconazole resistant, 1 intermediately sensitive, 10/11 were either fully or intermediately sensitive to voriconazole. All had received prior fluconazole and clotrimazole and 10/11 had used at least 2-weeks of one or more second-line antifungals with non-clearance of the yeast. Oral voriconazole 400 mg BD day-1, then 200 mg BD 13-days was prescribed and 10/11 women completed the course. Concomitant topical treatment was used by 6/11. Liver and renal function were monitored at 0, 7, 14 days. One woman stopped voriconazole after 5-days due to perioral tingling. Other transient side-effects were nausea ( n = 2), photosensitivity, muscle aches, hair thinning (all n = 1), peripheral visual disturbance ( n = 2). 8/11 experienced both symptom reduction and yeast clearance. Two women had an initial partial response but experienced resolution of symptoms following a second course of voriconazole. Conclusions Our observational data adds to the limited evidence to support voriconazole treatment for RVVYI. A 2-week course of voriconazole was tolerated and completed by 10/11 women. Eight women, five using concomitant topical agents, achieved mycological cure.
OCT-A in chronic central serous chorioretinopathy treated with oral eplerenone and half-fluence photodynamic therapy: A comparative study
Authors: Clemente Lidia , Cennamo Gilda , Montorio Daniela , Fossataro Federica , Passaro Maria Laura , Costagliola Ciro 
Published: October 2022

Purpose To evaluate retinal and choriocapillary vessel density (VD) changes in patients with chronic central serous chorioretinopathy (CSC) treated with half-fluence verteporfin photodynamic therapy (vPDT) or eplerenone, using optical coherence tomography angiography (OCTA). Methods Patients affected by CSC and treated with vPDT and eplerenone were retrospectively studied. At baseline and 3 months after each treatment, all patients underwent a complete ophthalmological examination, including an evaluation of best-corrected visual acuity (BCVA), slit-lamp biomicroscopy, fundus examination, fluorescein angiography (FA), indocyanine green angiography (ICGA), spectral-domain optical coherence tomography (SD-OCT) and OCTA. Results Forty-eight eyes of patients with CSC were analysed. Twenty-four eyes were placed in the vPDT group, and 24 eyes formed the eplerenone group. In both groups, OCTA showed a significant improvement in the VD of deep capillary plexus (DCP) and choriocapillaris (CC) after treatments with respect to baseline (p < 0.001), whereas the VD of superficial capillary plexus (SCP) did not show significant differences (p > 0.05). The PDT group demonstrated a statistically significant increase in the VD of DCP and CC with respect to the eplerenone group (DCP p = 0.012; CC p = 0.004). A statistically significant reduction with respect to baseline in subfoveal choroidal thickness (SFCT) (p = 0.001 for vPDT group; p = 0.001 for eplerenone group) and in central foveal thickness (CFT) (p = 0.001 for vPDT group; p = 0.001 for eplerenone group) was also found. The SFCT was significantly thinnest in the PDT group with respect to the eplerenone group (p = 0.021). Conclusion OCTA allowed us to study retinal and choriocapillary vascular changes in patients with CSC treated with vPDT and eplerenone.
Efficacy and safety after posterior chamber Implantable Collamer Lens implantation according to preoperative anterior chamber depth: Short-term comparative study
Authors: Silva Rui , Franqueira Nuno , Faria-Correia Fernando , Mendes José , Oliveira Mariana , Monteiro Tiago 
Published: October 2022

Purpose To compare visual, refractive, and safety outcomes of posterior chamber Implantable Collamer Lens (ICL) implantation for the correction of myopia according to the preoperative anterior chamber depth (ACD). Methods Retrospective, comparative study, patients submitted to implantation of myopic posterior-chamber phakic Implantable Collamer Lens (ICL), model V4C/V5, minimum follow-up of 12 months; two groups were created: Group 1 (ACD 2.80 to 2.99 mm) and Group 2 (ACD equal to or greater than 3.00 mm). The parameters evaluated were uncorrected and corrected visual acuity, subjective refraction, efficacy and safety index, predictability, endothelial cell density, central vault, anterior chamber angle and postoperative complications. A total of 558 eyes from 298 patients were evaluated: 111 eyes (19.9%) in group 1 and 447 eyes (80.1%) in group 2. Results At 12 months, the efficacy index was similar in both groups ( p = 0.264); the safety index was higher in group 1 ( p = 0.031); the mean central Vault was significantly lower in group 1 (212.8 vs 410.6 μm; p < 0.001). Respectively, 93 (83.8%) and 366 (84.1%) eyes were within ±0.50 D of targeted refraction. Anterior chamber angle significantly decreased during follow-up in both groups ( p < 0.001; p < 0.001). Intraocular pressure did not change significantly ( p = 0.310 and p = 0.446, respectively). There were no significant differences in endothelial cell density loss ( p = 0.278) or in the rate of complications observed ( p = 0.733). Conclusions ICL implantation is an effective and safe procedure in eyes with shallow anterior chambers, with visual and refractive results and complication rates identical to those obtained in deeper anterior chambers.
Increased hip flexion angle and protrusion of the anterior acetabular component can predict symptomatic iliopsoas impingement after total hip arthroplasty: a retrospective study
Authors: Tamaki Yasuaki , Goto Tomohiro , Wada Keizo , Omichi Yasuyuki , Hamada Daisuke , Sairyo Koichi 
Published: October 2022

Background: Iliopsoas impingement (IPI) is a known complication of total hip arthroplasty (THA). The aim of this study was to identify risk factors and the cut-off cup protrusion length for symptomatic IPI. Methods: We retrospectively reviewed 218 hips (46 men, 172 women) of 190 consecutive Japanese patients who underwent primary THA at our institution. Hips with IPI ( n = 24) and control hips ( n = 194) were compared according to age, body mass index, and clinical scores. We evaluated leg-length discrepancy, global offset, implant alignment angles, pelvic inclination, and anterior cup protrusion on plain radiographs and computed tomography scans. Results: Symptomatic IPI had an incidence of 11.0% and a predilection for hips with osteonecrosis. Pre- and postoperative hip flexion angles were significantly greater in hips with symptomatic IPI ( p = 0.013 and p = 0.006, respectively). Cup protrusion length was significantly greater in hips with IPI (4.7 mm vs. 1.4 mm; p = 0.001). Receiver-operating characteristic curve analysis identified a threshold cup protrusion length of 3.9 mm (sensitivity 0.89, specificity 0.63) for symptomatic IPI. The incidence of symptomatic IPI tended to be lower in patients with greater posterior pelvic sagittal inclination despite the cup protrusion length being greater. Conclusions: An increased hip flexion angle and protrusion of the anterior acetabular component predicted symptomatic IPI. The threshold cup protrusion length suggesting mild IPI might be about 3.9 mm and could be useful for identifying candidates for conservative treatment.