bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing Influenza Vaccination Coverage Among An Urban Pediatric Asthma Population: A Geospatial Analysis
Authors: Parker Sarah , DeLaroche Amy , Hill Alex , Arora Rajan , Gleason-Comstock Julie 
Published: March 2022

Abstract
Background: Asthma is the most common chronic disease in children. Children with asthma are at high risk for complications from influenza; yet, annual influenza vaccination rates are suboptimal. The overall aim of this study was to describe the characteristics of a high-risk group of children with asthma according to influenza vaccination status. Methods: The study was a retrospective chart review of 4355 patients aged 2 to 18 years evaluated in the pediatric emergency department (PED) between November 1, 2017 and April 30, 2018 with an ICD-10-CM code for asthma (J45.x). Eligible patient PED records were matched with influenza vaccination records for the 2017-2018 influenza season from the Michigan Care Improvement Registry. Geospatial analysis was employed to examine the distribution of influenza vaccination status. Results: 1049 patients (30.9%) with asthma seen in the PED had received an influenza vaccine. Influenza vaccination coverage varied by Census Tract, ranging from 10% to >99%. Most vaccines were administered in a primary care setting (84.3%) and were covered by public insurance (76.8%). The influenza vaccination rate was lowest for children aged 5-11 (30.0%) years and vaccination status was associated with race (p<0.001) and insurance type (p<0.001). Conclusions: Identification of neighborhood Census Tract and demographic groups with suboptimal influenza vaccination could guide development of targeted public health interventions to improve vaccination rates in high-risk patients. Given the morbidity and mortality associated with pediatric asthma, a data-driven approach may improve patient outcomes and reduce healthcare-associated costs.
How Does Spiritual Leaders Inspire Employees' Innovative Behavior? The Role of Psychological Capital and Intrinsic Motivation
Authors: Li Bin , Lei Yongxin , Hu Mingqi , Li Wenjing 
Published: March 2022

Abstract
Spiritual leadership is an emerging type of leadership that focuses on using intrinsic motivation to help subordinates achieve spiritual enrichment and thus motivate employees to work. This study adopts the method of questionnaire to investigate 886 employeess of Chinese companies in three stages, and tests the mediating effect by using the bootstrap method. Our results showed that: (1) Spiritual leadership had a positive correlation on employeess' innovative behavior; (2) both psychological capital and intrinsic motivation mediated the relationship between spiritual leadership and innovative behavior; (3) we found a sequential mediating effect between spiritual leadership and followers’ innovative behavior. The findings deepened our understanding of the psychological mechanisms by which the spiritual leadership inspires innovative behavior, and provide a practical reference for managers to stimulate individual innovative behavior.
Evaluation of optical coherence tomography findings and visual evoked potentials in Charcot-Marie-Tooth disease
Authors: Kaplan Aysin Tuba , Yalcin Sibel Oskan , Sager Safiye Gunes , Türkyılmaz Ayberk , İnan Rahşan 
Published: March 2022

Abstract
Purpose: To evaluate the spectral-domain optical coherence tomography (SD-OCT) findings and pattern visual evoked potential (VEP) in Charcot-Marie-Tooth (CMT) disease.Methods: Seventeen patients with CMT disease and 17 control subjects were included in the study. The patients were divided into two groups according to conduction velocity and inheritance pattern as demyelinating type (CMT 1) and axonal type (CMT 2). The average retinal nerve fiber layer (RNFL) thickness, RNFL thicknesses of all quadrants, and thicknesses of the ganglion cell layer complex (GCC) were measured using SD-OCT. Pattern VEP recordings were evaluated in both groups.Results: The average and four quadrants of RNFL thicknesses, and superior and inferior GCC thicknesses were significantly thinner in the CMT patients compared with healthy individuals, but there were no statistically significant differences between the CMT groups. There was a significant positive correlation between age and all RNFL and GCC thicknesses in the CMT 2 group and between age and RNFL thickness of the temporal quadrant in the CMT 1 group. P100 latencies were significantly delayed in the CMT groups compared with controls and there were no significant differences in P100 latencies between the CMT groups (p<0.001). VEP amplitudes were in normal ranges in the CMT groups.Conclusion: This study showed that RNFL and GCC thicknesses were significantly reduced and VEP latencies were prolonged in patients with CMT with normal clinical examinations. Our results suggest that optic nerves may be affected more frequently in patients with CMT than is detected in clinical examinations.
Repairing of Missing Data in Scheduling Based on Generative Adversarial Network
Authors: Chen Jing , Song Ying , yi guodong , Zhang Shuyou , Bu Wanghui 
Published: March 2022

Abstract
In the manufacturing process of modern smart factories, when product family design and variant design are carried out on the basis of existing products, local design changes will generate new technological processes. Process changes lead to partial lack of scheduling data, which in turn affects the efficiency of workshop scheduling in the manufacturing process. most of the research results related to scheduling problems are focused on the optimization of various scheduling objectives, without considering the problem of missing scheduling data. Therefore, this paper proposes a data processing method that combines missing data removal and data expansion based on processing order for optimal training of GAN to solve the problem of insufficient training data when the scheduling data set is small. In this paper, We use GAN to generate local data, and combine the missing vector of the data and the hint vector to strengthen the training process, complete the repair of the missing data, and then further study the effectiveness of the repair. Experimental results show that this method of using historical process data to repair scheduling data can effectively repair the problem of partial missing data in the same product family and improve the efficiency of workshop production scheduling.
Doppler Ultrasonography of Ocular Blood Flow in Non–glaucoma versus Primary Open Angle Glaucoma Subjects at University of Nigeria Teaching Hospital, Enugu
Authors: Onwubiko Stella Ngozi , Nwachukwu Nkiru Zuada , Nkwegu Ogbonna Markson , Arinze Ifeoma , Onwasigwe Ernest Nnaemeka , Umeh Rich Enujioke 
Published: March 2022

Abstract
Purpose: To evaluate and compare the ocular blood flow in non-glaucoma versus primary open-angle glaucoma (POAG) subjects attending the ophthalmic clinic of University of Nigeria Teaching Hospital (UNTH) Enugu using Doppler ultrasonography. Methods: A cross-sectional comparative study was adopted. Fifty-Eight POAG and 58 non-glaucoma subjects were recruited. Information on their socio-demographic and clinical profiles was obtained via an interviewer-administered questionnaire. Ocular Doppler Imaging was performed on all the Subjects. Peak systolic volume, End diastolic volume, mean flow velocity and Resistive Index (RI) of the central retinal artery and ophthalmic artery were recorded. Data were analysed using the SPSS version 21. Person correlation was used to determine the relationship between the Doppler indices and demographic and clinical variables. The level of significance was at p <0.05.Results: The subjects were mainly males, 71(61.7%), with an age range of 40 to 79 years. The POAG Subjects lived with glaucoma for 5.57±4.2 years, and mainly on medical treatment 52(89.7%) with beta-blockers and prostaglandin analogues. The RI was significantly higher (p=0.01) in POAG subjects. A significant positive relationship (P = 0.014) was observed between RI and intraocular pressure (IOP) of the POAG subjects.Conclusion: In POAG subjects, RI was significantly higher; as the IOP increased there was an increase in RI translating to a sub-optimal ocular blood flow. Interventions aimed at modifying the RI would therefore be synergistic with IOP lowering measures. Additionally, RI assessment may offer a new target for glaucoma case finding.
Radar-Based Timed Up And Go Test For Multiperson Providing A Risk Of Falling Assessment
Authors: Ayena Johannes C. , Chioukh Lydia , Deslandes Dominic 
Published: March 2022

Abstract
Objective: Over the past decade, the research community has made major advances in technologies for detecting risk of falling in elderly, which led to assistive systems that can help to improve physical strength and limit isolation. However, it is still expensive to extend these systems to a multi-user performing a clinical test, such as the Timed Up and Go (TUG). In this paper, we therefore propose a new avenue, a radar-based system that transcends these limitations. Results: The proposed methodology is evaluated using data from real-world scenarios. It is found that distinguishing two participants performing a TUG test at the same time is more accurate when they are walking in opposite direction compared to perfectly synchronized walking in the same direction. However, although it was more challenging to distinguish two participants in this latter scenario, our results show that when they are offset by a certain distance, the proposed algorithm can track them separately. Our goal was therefore to relieve congestion in medical settings by investigating the feasibility of administering a clinical test with more than one participant at the same time thanks to an UWB radar sensor.
Algerian Registry for Inborn Errors of Immunity in Children: Report of 887 children (1985 - 2021)
Authors: Yagoubi Abdelghani , Tahiat Azzeddine , Touri Nabila Souad , Ladj Mohamed Samir , Drali Ouardia , Belaid Brahim , Mohand-Oussaid Ayda , Dehimi Abdelhak , Belbouab Reda , Ferhani Yacine , Melzi Souhila , Guedouar Assia , Hakem Saliha , Khemici Ouardia , Inouri Yacine , Meddour Yanis , Dib Saadeddine , Mansouri Zohra , Iddir Samir , Boufersaoui Abderrahmane , Boudiaf Houda , Bouhdjila Abderrachid , Ibsaine Ouardia , Maouche Hachemi , Dahlouk Djazia , Mekki Azzedine , Bioud Belkacem , Bouzerar Zahir , Zeroual Zoulikha , Benhassine Fadila , Bekkat-Berkani Dahila , Naamoune Soumeya , Salah Samir Sofiane , Chaib Samia , Attal Nabila , Bensaadi Nadia , Bouchair Nadira , Cherif Nacira , Kedji Leila , Bendeddouche Salih , Atif Mohamed Lamine , Djenouhat Kamel , Kechout Nadia , Djidjik Reda , Benhalla Keltoum Nafissa , Smati Leila , Boukari Rachida 
Published: March 2022

Abstract
Introduction: Inborn errors of immunity (IEI) represent a heterogeneous large group of genetic disorders characterized by susceptibility of affected individuals to recurrent infections, autoimmune/inflammatory diseases, allergies and malignancy. We aim to report for the first time the Algerian registry for IEI in children.Methods: We describe the characteristics of IEI in Algerian children from the data collected in the Algerian registry for IEI over a long period of 37 years.Results: Between 1985 and 2021, we included 887 children (530 male, 59.6%) with a mean age at diagnosis of 3.23y and a mean diagnosis delay of 2y. The prevalence rate was estimated at 1.97/100,000 inhabitants or 5.91/100,000 children. The parental consanguinity was found in 52.6%. The most prevalent category was combined immunodeficiencies (CID) (35.5%) followed by predominantly antibody deficiencies (24.4%) and CID with syndromic features (17.9%). The most predominant diseases were severe CID (120 cases), MHC II deficiency (99 cases), agammaglobulinemia (81 cases), common variable immunodeficiency (74 cases), hyper IgE syndromes (60 patients), ataxia telangiectasia (46 patients), Wiskott Aldrich syndrome (40 patients) and chronic granulomatous disease (39 cases). The clinical presentation was dominated by lower respiratory tract infections (69%), failure to thrive (38.3%) and chronic diarrhea (35.2%). Genetic analysis was performed in 156 patients (17.6%). The global mortality rate was 28.4% mainly caused by CID.Conclusion: This is the first report of the Algerian registry for IEI in children. Data is globally similar to that of Middle East and North African (MENA) registries with high consanguinity, predominance of CID, and significant mortality. This registry highlights the weak points that should be improved in order to provide better patient care.
When Host Populations Move North, but Disease Moves South: Counter-intuitive Impacts of Climate Warming on Disease Spread
Authors: Moran E. Joe , Martignoni Maria , Lecomte Nicolas , Leighton Patrick , Hurford Amy 
Published: March 2022

Abstract
Empirical observations and mathematical models show that climate warming can lead to the northern (or, more generally, poleward) spread of host species ranges and their corresponding diseases. Here, we explore an unexpected possibility whereby climate warming induces disease spread in the opposite direction to the directional shift in the host species range. To test our hypothesis, we formulate a reaction-diffusion equation model with a Susceptible-Infected (SI) epidemiological structure for two host species, both susceptible to a disease, but spatially isolated due to distinct thermal niches, and where prior to climate warming the disease is endemic in the northern species only. Previous theoretical results show that species’ distributions can lag behind species’ thermal niches when climate warming occurs. As such, we find that climate warming, by shifting both species' niches forward, may increase the overlap between northern and southern host species ranges, due to the northern species lagging behind its thermal tolerance limit, thus facilitating a southern disease spread. As our model is general, our findings may apply to viral, bacterial, and prion diseases that do not have thermal tolerance limits and are inextricably linked to their hosts’ distributions, such as the spread of rabies from arctic to red foxes.
Persistence of conjunctival colonization by coagulase-negative staphylococci in patients undergoing cataract surgery
Authors: Samudio Margarita , Abente Sonia , Fariña Norma , López Yolanda , Carolina Carolina , Laspina Florentina , Guillén Rosa , Salinas Claudia de los Ángeles , Castillo Verónica , Nentwich Martin 
Published: March 2022

Abstract
PurposeTo establish the conjunctival contamination source by coagulase-negative staphylococci (CNS) during cataract surgery and discuss the implications of this colonization as a potential risk of acquiring endophthalmitis.Methods Conjunctiva samples for culture from 59 patients undergoing cataract surgery were taken of the fellow eye at baseline (T1) and from the eye to be operated before (T0) and immediately after (T2) irrigation with povine-iodine IOP5%, and at the end of surgery (T3). Genes responsible for virulence (mecA, ica and atlE) and antibiotic profile were determined; strain clonality of persistent colonizing S. epidermidis strains was established by the Multi-locus sequence typing (MLST).Results The frequency of CNS was significantly reduced in T2 (13.6%) from 81.4% in T0 and 86.4% in T1. The frequency of mecA, ica and atlE genes was 35.9%, 41.7% and 67.2%, respectively; and methicillin phenotypic resistance was 35.4%. S. epidermidis was the most frequent species isolated in every time point. MLST revealed in 7 patients 100% coincidence of the 7 alleles of the S. epidermidis isolated previous to povine-iodine 5% disinfection and at the end of the surgery. CNS isolates from T2 or T3 corresponded to the same species, antibiotic and virulence profile as those isolates from T1 or T0.Conclusion Pre-surgical prophylactic scheme significantly reduced conjunctival contamination; in those that persisted, the source of contamination was mostly the patient's microbiota confirmed by the MLST system.
One-step synthesis and characterization of hydrophilic polymer microspheresimmobilized with polyphenylsulfone ultrafiltration membranes for protein rejection application
Authors: Rajashekhara Panchami Heggabailu , Isloor Arun M. , Ismail Ahmad Fauzi 
Published: March 2022

Abstract
An effective single-step polymerization was followed for the synthesis of hydrophilicP(MBAm-co-MAA) microspheres. The distillation-precipitation polymerization (DPP) technique utilized N,N՛- methylenebis(acrylamide) (MBAm) as a crosslinker, methacrylic acid (MAA) as a monomer, solvent acetonitrile (ACN) and an initiator 2,2-azobisisobutyronitrile (AIBN) for synthesizing the P(MBAm-co-MAA) polymer particle.Simultaneously, in the reaction system, the polymer particles were formed as a precipitateand acetonitrile from the reaction was distilled out. The reaction takes placewithoutaddition of any surfactant or stabilizers. The morphology of the resultant microspheres, which were characterized by field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), attenuated total reflectance fourier-transform infrared spectroscopy (ATR-FTIR), X-ray diffraction (XRD), thermogravimetric analysis (TGA)and Brunauer-Emmett-Teller (BET) analysis.These microspheres were used as an additive for improving the performance of the fabricated membrane. The modified membranes showed increased hydrophilicity, porosity and water uptake.Membranes also exhibitedimproved permeability (63.7 Lh-1m-2bar-1), flux recovery ratio (80.7%)andthe highest protein rejection values of 94.8% (bovine serum albumin), 68.4% (pepsin), 86.9% (egg albumin) were observed. Therefore, the as-prepared membrane can potentially beusedfor protein removal from industrial wastewater.
The surface density profile of a lens galaxy is 97.6 per cent elliptical power-law
Authors: Powell Devon , Vegetti Simona , McKean John , Spingola Cristiana , Stacey Hannah , Fassnacht Chris 
Published: March 2022

Abstract
The projected density profiles of gravitational lens galaxies are often assumed to be consistent with a simple elliptical power-law. Previous studies at low angular resolution have found this description to be satisfactory, but the limitations of this smooth model assumption have not yet been observationally tested. Here we report the analysis of a gravitational lens system observed at milli-arcsecond angular resolution with very long baseline interferometry at 1.7 GHz using a state-of-the-art Bayesian lens modelling technique for interferometric data. An elliptical power-law mass distribution is found to be a remarkably good description of the data, but there remain source-plane light components that are misaligned by several milli-arcseconds. The addition of angular multipole perturbations gives a significantly better fit (Bayes factor of +4751), while the best-focused source model is recovered using pixellated corrections to the lens potential. The projected density in our best model deviates from an elliptical power-law by 2.4 per cent (RMS) inside a region within 17 mas of the lensed images. The assumption of a perfect elliptical power-law would bias the measurement of H_0 by +0.6 per cent, and the observed flux ratios by up to 10.3 per cent, for this lens. Our results demonstrate that low-level density perturbations exist in this massive elliptical galaxy. Their presence can significantly affect studies of galaxy formation via flux-ratio anomalies, but do not strongly affect time-delay measurements of the Hubble constant.
Acute Placental Insufficiency Two Weeks After an Asymptomatic COVID-19 Maternal Infection: The Deleterious Effects of The SARS-Cov-2 Placentitis Associated with B.1.617.2 (Delta) Variant. Report of Two Cases.
Authors: Chiaie Loredana Delle , Stolpner Ilona , Baltz-Ghahremanpour Katrin 
Published: March 2022

Abstract
We present two cases of acute severe placental insufficiency in the late second trimester and in the third trimester of pregnancy, emerging within 14 days following a mild COVID-19 (Delta variant) disease in two not vaccinated healthy women with hitherto unremarkable pregnancies. The pathognomonic histopathological findings and the RT-PCR positivity of the placenta suggest the SARS-CoV-2 placentitis as the possible cause of the severe fetal distress. At present, propagation of vaccination and a strict feto-maternal surveillance in the first weeks after maternal infection seem to be the only way to protect the gestation from the risks of acute placental insufficiency associated with the SARS-CoV-2 infection.
Biotic interactions prior to seed dispersal determine recruitment probability of peyote (Lophophora diffusa, Cactaceae), a threatened species pollinator-dependent
Authors: Briseño-Sánchez María Isabel , Martorell Carlos , Valverde Pedro Luis , Mandujano Maria Carmen 
Published: March 2022

Abstract
Seedlings recruitment is key to maintaining populations and depends on diverse biotic interactions before and after seed dispersal. Cacti recruitment is infrequent and occurs at sporadic pulses associated with rainy years. Furthermore, biotic interactions can limit seeds availability due to scarce or inefficient pollinators, dispersers or to antagonistic interactions with florivores and seed predators, as cactus depend on animals for pollination and dispersal. We identified interactions and traits involved in the regeneration process of Lophophora diffusa, during seven-years (2015–2021). We assessed floral rewards, pollination rates, intensity of florivory and seed removal, to estimate the probability of recruitment in a population located in Queretaro, Mexico. We found that pre-dispersal events reduced recruitment as flower–fruit transition has a low probability. High florivory and low pollinator visitation rate due to low nectar availability decreased seed formation in all years. Seed predation was not limiting recruitment, since most seeds escaped predation. Even so, a low proportion of seeds established as seedlings, possibly due to water limitation or seed dormancy. The interactions with pollinators and florivores decreased ovule-seed transition, once the seeds are formed, there is a high probability of evade predation. Hence, pre-dispersal interactions during flowering determine the availability of seeds, and reduce recruitment in peyote, rather than post-dispersal interactions.