bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distinct care trajectories among persons living with arthritic conditions: A two-year state sequence analysis
Authors: Nguena Nguefack Hermine Lore , Pagé M. Gabrielle , Choinière Manon , Vanasse Alain , Deslauriers Simon , Angarita-Fonseca Adriana , Blanchette Marc-André , Lacasse Anaïs 
Published: November 2022

ObjectivesDeveloping solutions to optimize care trajectories (CareTs) requires examining patient journeys through the health care system. This study aimed to describe CareTs among people living with arthritis and evaluate their association with self-reported health outcomes.MethodsAnalyses were conducted using the TorSaDE Cohort (n = 102,148), which connects the 2007 to 2016 Canadian Community Health Surveys (CCHS) with Quebec administrative databases (longitudinal claims). CareTs of participants living with arthritis according to CCHS (n = 16,631), over the two years before CCHS completion, were clustered using state sequence analysis (months as a time unit). CareT group membership was then put in association with self-reported outcomes (pain intensity and interference, self-perceived general and mental health).ResultsThe analysis revealed five CareT groups characterized predominantly by: (1) arthritis-related visits to a specialist (n = 2,756; 16.6%), (2) arthritis-related emergency department visits (n = 2,928; 17.6%), (3) very high all-cause health care utilization and arthritis-related hospitalizations (n = 1,570; 9.4%), (4) arthritis-related medical visits to general practitioners and specialists (n = 2,708; 16.3%), (5) low all-cause health care utilization (n = 6,669; 40.1%). Multivariable results revealed that CareT group membership was associated with higher levels of pain interference (CareT group #3 vs. #5: OR: 1.4, 95%CI: 1.1–1.8) and fair/poor self-perceived general health (CareT group #1 vs. #5: OR: 1.551, 95%CI: 1.319–1.824; #2 vs. #5: OR: 1.244, 95%CI: 1.062–1.457; #3 vs. #5: OR: 1.771, 95%CI: 1.451–2.162; #4 vs. #5: OR: 1.481, 95%CI: 1.265–1.735).DiscussionSate sequence analysis is an innovative method of studying CareTs and valuable for making evidence-based decisions taking into account inter- and intra-individual variability.
Assessment of choroidal vascularity and choriocapillaris blood perfusion in Chinese preschool-age anisometropic hyperopic amblyopia children
Authors: Hui Wang , Xiaofeng Hu , Hua Xin , Yihan Dong , Yong Tao 
Published: November 2022

PurposeTo determine the macular and peripapillary area choroid microstructure parameters of hyperopic anisometropic amblyopia eyes and compare to fellow and age-matched control eyes. To assess the correlation between the axial length (AL), choroidal thickness (CT) and choroid microstructure parameters.MethodsThis cross-sectional comparative, non-interventional study involved 52 hyperopic anisometropic amblyopia children and 48 age-matched heathy controls. 52 eyes with hyperopic anisometropic amblyopia and 48 age-matched control eyes were studied. The peripapillary and subfoveal CT were determined. The total choroidal area (TCA), luminal area (LA), and stromal area (SA) of the subfoveal and peripapillary choroid were measured. In addition, the correlation between the AL, CT and choroid microstructure parameters were calculated.ResultsThe peripapillary and subfoveal CT of the amblyopic eyes was significantly thicker than the fellow and control eyes (all P &lt; 0.05). The subfoveal and peripapillary choroidal SA, LA and TCA of the amblyopic eyes were significantly increased than that of the fellow and control eyes (all P &lt; 0.05). The choroidal vascularity index (CVI) values of the amblyopic eye were significantly different among the three groups (P &lt; 0.05). There was a statistically significant negative correlation between AL and subfoveal CT (SFCT), LA and TCA levels (P &lt; 0.001, P = 0.039, P = 0.027, respectively). Spherical equivalent (SE) was positive correlated with SFCT, LA and TCA levels (P = 0.456, 0.229 and 0.240, respectively; all P &lt; 0.05). There was a statistically significant positive correlation between SFCT, SE, LA, SA, TCA and CVI levels (all P &lt; 0.05).ConclusionThe subfoveal and peripapillary CT of amblyopic children abnormally increased and correlated with shorter AL and higher SE. The choroidal structure of the amblyopic eyes was different from the fellow and control eyes, the hyperopic anisometropic amblyopic eyes had significantly thicker sub-foveal choroid, higher LA, SA, and TCA. AL and CT affect choroidal structure and vascular density. Choroidal blood flow may be increased in amblyopic eyes. The larger LA, SA, TCA, and lower CVI were characteristic of the amblyopic eye.
Filling the gaps in the research about second primary malignancies after bladder cancer: Focus on race and histology
Authors: Othmane Belaydi , Yi Zhenglin , Zhang Chunyu , Chen Jinbo , Zu Xiongbing , Fan Benyi 
Published: November 2022

PurposePrevious research has shown that bladder cancer has one of the highest incidences of developing a second primary malignancy. So, we designed this study to further examine this risk in light of race and histology.Patients and methodsUsing the surveillance, epidemiology, and end results (SEER) 18 registry, we retrospectively screened patients who had been diagnosed with bladder cancer between 2000 and 2018. We then tracked these survivors until a second primary cancer diagnosis, the conclusion of the trial, or their deaths. In addition to doing a competing risk analysis, we derived standardized incidence ratios (SIRs) and incidence rate ratios (IRRs) for SPMs by race and histology.ResultsA total of 162,335 patients with bladder cancer were included, and during follow-ups, a second primary cancer diagnosis was made in 31,746 of these patients. When the data were stratified by race, SIRs and IRRs for SPMs showed a significant difference: Asian/Pacific Islanders (APIs) had a more pronounced increase in SPMs (SIR: 2.15; p 0.05) than White and Black individuals who had an SIRs of 1.69 and 1.94, respectively; p 0.05. In terms of histology, the epithelial type was associated with an increase in SPMs across all three races, but more so in APIs (IRR: 3.51; 95% CI: 2.11–5.85; p 0.001).ConclusionWe found that race had an impact on both the type and risk of SPMs. Additionally, the likelihood of an SPM increases with the length of time between the two malignancies and the stage of the index malignancy.
Excess mortality in Poland during the first and second wave of the COVID-19 pandemic in 2020
Authors: Pikala Małgorzata , Krzywicka Małgorzata , Burzyńska Monika 
Published: November 2022

PurposeThe aim of the study was to analyse excess deaths by major causes of death and associated changes in the mortality pattern of the Polish population in 2020 due to the impact of the COVID-19 pandemic.MethodsThe study used data on all deaths in Poland which occurred between 2010 and 2020 (N = 3,912,237). 10-year mortality trends for 2010–2019 were determined. An analysis of time trends has been carried out with joinpoint models and Joinpoint Regression Program. Based on the determined regression models, the number of deaths expected in 2020 and the number of excess deaths due to selected causes were calculated.ResultsThe crude death rates of all-cause deaths increased from 2000 to 2019 at an average annual rate of 1% (p = 0.0007). The determined regression model revealed that the number of deaths in 2020 should have been 413,318 (95% CI: 411,252 to 415,385). In reality, 477,355 people died in Poland that year. The number of excess deaths was therefore 64,037 (15.5%). According to data from Statistics Poland the number of COVID-19-related deaths was 40,028, the number of non-COVID-19 deaths was 24,009. The largest percentage increase over the expected number of deaths was observed for suicide (12.5%), mental and behavioral disorders (7.2%) and diseases of circulatory system (5.9%). A lower than expected number of deaths was observed for malignant neoplasms (−3.2%) and transport accidents (−0.1%).ConclusionThe difference between expected and observed non-COVID-19 deaths in 2020 indicates a need for further analysis of the causes of excess mortality.
Living alone is associated with a higher prevalence of psychiatric morbidity in a population-based cross-sectional study
Authors: Chen Te-Yu , Geng Jiun-Hung , Chen Szu-Chia , Lee Jia-In 
Published: November 2022

BackgroundLiving alone has been linked to poor mental health, however large-scale epidemiological studies on the association between living alone and psychiatric morbidity including depression and anxiety are lacking. The aim of this study was to investigate this issue in a large Taiwanese cohort.MethodsIn this cross-sectional study, we enrolled 121,601 volunteers from 29 community recruitment stations in Taiwan and divided them into two groups based on whether or not they lived alone. Psychiatric morbidity was defined as a Generalized Anxiety Disorder 2-item score ≥ 3, Patient Health Questionnaire 2-item score ≥ 3, or self-reported depression. Logistic regression was used to explore the associations between living alone and psychiatric morbidity.ResultsThe participants who lived alone had a higher prevalence of psychiatric morbidity [odds ratio (OR) = 1.608, 95% confidence interval (CI) = 1.473 to 1.755] after adjusting for potential confounders. In a subgroup analysis, married subjects who lived alone and divorce/separation (OR = 2.013, 95% CI = 1.763 to 2.299) or widowing (OR = 1.750, 95% CI = 1.373 to 2.229) were more likely to have psychiatric morbidity than those who were married and not living alone.ConclusionsOur findings suggest that living alone is a risk factor for psychiatric morbidity, especially for married subjects who live alone in concordance with divorce, separation, or the death of a spouse.
Randomized placebo-controlled trial of feline-origin Enterococcus hirae probiotic effects on preventative health and fecal microbiota composition of fostered shelter kittens
Authors: Gookin Jody L. , Strong Sandra J. , Bruno-Bárcena José M. , Stauffer Stephen H. , Williams Shelby , Wassack Erica , Azcarate-Peril M. Andrea , Estrada Marko , Seguin Alexis , Balzer Joerg , Davidson Gigi 
Published: November 2022

IntroductionDiarrhea is the second most common cause of mortality in shelter kittens. Studies examining prevention strategies in this population are lacking. Probiotics are of particular interest but studies in cats are largely limited to healthy adults or those with induced disease. Only one study in domestic cats describes the use of host-derived bacteria as a probiotic. We previously identified Enterococcus hirae as a dominant species colonizing the small intestinal mucosa in healthy shelter kittens. Oral administration of a probiotic formulation of kitten-origin E. hirae (strain 1002-2) mitigated the increase in intestinal permeability and fecal water loss resulting from experimental enteropathogenic E. coli infection in purpose-bred kittens. Based on these findings, we hypothesized that administration of kitten-origin E. hirae to weaned fostered shelter kittens could provide a measurable preventative health benefit.MethodsWe conducted a randomized, placebo-controlled, blinded clinical trial to determine the impact of a freeze-dried E. hirae probiotic on body weight gain, incidence of diarrhea, carriage of potential diarrheal pathogens, and composition of the intestinal microbiota in weaned fostered shelter kittens.ResultsOne-hundred thirty kittens completed the study. Fifty-eight kittens received the probiotic and 72 received the placebo. There were no significant differences in age, weight upon initiation of the study, number of days in the study, average daily gain in body weight, or weight at completion of the study. Kittens treated with E. hirae were 3.4 times less likely to develop diarrhea compared to kittens treated with placebo (odds ratio = 0.294, 95% CI 0.109–0.792, p = 0.022). A significant impact of E. hirae was not observed on the presence or abundance of 30 different bacterial, viral, protozoal, fungal, algal, and parasitic agents in feces examined by qPCR. With exception to a decrease in Megamonas, administration of the E. hirae probiotic did not alter the predominant bacterial phyla present in feces based on 16S rRNA gene amplicon sequencing.DiscussionDecreased incidence of diarrhea associated with preventative administration of E. hirae to foster kittens supports a rationale for use of E. hirae for disease prevention in this young population at high risk for intestinal disease though additional studies are warranted.
Efficacy of Artemisia annua against Coccidiosis in Broiler Chickens: A Field Trial
Authors: Coroian Mircea , Pop Loredana Maria , Popa Virgilia , Friss Zsuzsa , Oprea Ovidiu , Kalmár Zsuzsa , Pintea Adela , Borșan Silvia-Diana , Mircean Viorica , Lobonțiu Iustina , Militaru Dumitru , Vârban Rodica , Györke Adriana 
Published: November 2022

(1) Background: Various studies on artemisinin and its derivatives have shown that Artemisia annua may be of therapeutic interest for different diseases, including chicken coccidiosis. This study aimed to evaluate the effects of Artemisia annua on farm-reared broiler chickens by analyzing both the anticoccidial efficacy and its effect on the intestinal microbiota of poultry. (2) Methods: The experiment was performed within three houses on a broiler chicken farm located in Romania. House 1 was the experimental group and received a diet with an addition of A. annua. Houses 2 and 4 were the control groups and received anticoccidials. The prophylactic efficacy of A. annua against coccidiosis was evaluated by recording the weight gain, feed conversion rate, number of oocysts per gram of feces, lesion score, and mortality rate. (3) Results: The chickens fed with A. annua showed a decreasing trend in the number of oocysts per gram of faeces, and their lesion score was 80% lower than in the control group. The weight gains of the chickens treated with A. annua was lower, whilst the feed conversion rate was better than in controls. (4) Conclusions: Artemisia annua showed promising results in the prophylaxis of coccidiosis. Overall, the broiler chickens that received A. annua presented promising zootechnical performances and medical data related to coccidiosis and gut microbiota.
Ácido giberélico na emergência e desenvolvimento de plântulas de Sapucainha
Authors: Souza Alejandro Pio de , Neto Bartouvino Costa , Grobério Rafaela Barreto Cazaroto , Cremonini Gustavo Miranda , Leite Kevilim de Jesus , Paixão Marcus Vinicius Sandoval , Fernandes Antônio Resende 
Published: November 2022

O Carpotroche brasiliensis, conhecida como “SAPUCAINHA”, é uma espécie arbórea semideciduária, da família Flacourtiaceae, encontrada nos estados do Espírito Santo, Minas Gerais, Bahia, Rio de Janeiro e São Paulo. É uma árvore de médio porte, 5 a 20 metros de altura. Seus frutos são atrativos para animais silvestres. Utilizada em áreas de restauração florestal sendo atrativo para fauna. A pesquisa foi realizada com objetivo de avaliar diferentes dosagens de giberelina no estímulo a germinação e desenvolvimento de plântulas de sapucainha. O experimento foi conduzido no viveiro de produção de mudas, com tela de poliolefina 50% de sombreamento, no viveiro do IFES, Campus Santa Teresa, submetendo as sementes aos seguintes tratamentos: imersão por uma hora em: água (testemunha); solução de giberelina a 1000 mg.L-1, 2000 mg.L-1, 3000 mg.L-1 e 4000 mg.L-1. O delineamento experimental foi inteiramente casualizado (DIC), com 5 tratamentos e quatro repetições, com cada unidade experimental composto de 25 sementes. Após 30 dias do início da germinação, foi avaliada a porcentagem de germinação (G) e após 60 dias da germinação, foi avaliado o número de folhas (NF); altura da planta (AP); comprimento da raiz (CR). Os dados experimentais foram submetidos à análise de variância, sendo as médias de cada característica comparada pelo teste de Tukey em nível de 5% de probabilidade. A concentração de 4.000 mg.L-1 de giberelina aplicada na pré-embebição de sementes de Sapucainha, apresentou nos melhores resultados na emergência e desenvolvimento inicial das plântulas, podendo ser indicada para esta espécie.
Physical therapy intervention in the treatment of insomnia
Authors: Russi Marcos Antonio , Sperandio Regiane Donizeti , De Oliveira Cintia Roque , Sanches Lívia Renata 
Published: November 2022

Introduction: The demands from every-day-life constantly cause more and more people to suffer from insomnia, becoming a worldwide epidemic that affects 40% of the population and leads to economic and social loss. Objective: evaluate Physiotherapy as a tool to reestablish the physiologic balance and consequent sleep improvement. Method: experimental research was conducted by applying physiotherapy techniques in 31 volunteers aged between 18 and 65 years old presented with insomnia. Each volunteer was submitted to 40-minute sessions twice a week for 10 sessions. Data collection was preceded by an initial and final evaluation through a questionnaire to analyze sleep quality. Salivary cortisol levels were measured and analyzed in partnership with the Hospital Israelita Albert Einstein. Results: 55% of the participants were female with mean age of 36.27 years old (±9.42) and 45% of participants were male with mean age of 36.10 years old (±10.77). Initially, 95% of these participants classified sleep as bad and by the end of the sessions 90% qualified sleep as good. At the beginning of the study, 80% reported the feeling of no having rested during sleep, at the end, this percentage dropped to 25%. Also, 75% of volunteers reported feeling sleepy during activities of daily living, but at the end this number dropped to 15%. Depression was reported in 35% of patients at the start of the study with total reversion by the end. Conclusion: the techniques used promoted an improvement in the volunteers’ sleep quality as well as a better daytime disposition.
Análise de eficiência energética em iluminação pública no cacau pirera município de Iranduba
Authors: Farias Kamylla Jenyffer Lopes , Pacheco Maria dos Anjos Fernandes , Pinheiro Érika Cristina Nogueira Marques 
Published: November 2022

A eficiente energética é um tema que atualmente vem crescendo bastante,a economia de energia elétrica é um assunto de grande importância, pelo fato do país se aproximar de uma possível crise energética. Entre os 25 países com maior consumo de energia no mundo, o Brasil ocupa 19º posição no ranking de eficiência energética de 2022, sendo um dos países com menos desprende esforços para implementação de soluções em eficiência energética em âmbito nacional. O presente trabalho estuda maneiras de reduzir o consumo de energia elétrica dos sistemas de iluminação pública através da utilização de equipamentos mais modernos e eficientes. Um estudo de caso foi realizado em uma região de cacau pirera município de Iranduba para analisar o sistema de iluminação existente e sugerir um método mais eficiente através da aplicação do um programa de eficiência energética da Agência Nacional de Energia Elétrica (ANEEL) com a finalidade de apresentar o resultado da pesquisa de estudo de caso, através da escolha do método retrofit , como a melhor forma de reduzir o consumo de energia.
Lip lifting como alternativa estética
Authors: Silva Talita Oliveira da , Rocha Marcos William Marques da , Varejão Lívia Coutinho 
Published: November 2022

Os lábios formam uma linha de transição entre a pele facial e a mucosa oral, sendo considerada a maior unidade de expressão móvel da face. Eles transmitem mensagens de forma deliberada e subconscientemente. Objetivo Geral: Elencar evidências acerca do procedimento de lip lifting a partir de uma revisão de literatura. Metodologia: A coleta das informações para a pesquisa bibliográfica se deu por meio da exploração da base de dados da Biblioteca Virtual em Saúde (BVS), Biblioteca Cientifica Eletrônica Virtual (SCIELO), PUBMED e MEDLINE. Resultados e Discussão: Através da busca na base de dados identificou 306 estudos, sendo excluídos 21 artigos por duplicidade e 267 artigos por não estar relacionado à temática. Posteriormente, realizou-se a leitura na íntegra dos artigos e aplicação dos critérios de seleção, nos quais foram excluídas 8 publicações, resultando na composição de 10 estudos primários na síntese final. Considerações Finais: A partir do desenvolvimento desse estudo foi possível elencar evidencias acerca do procedimento lip lifting, onde ficou compreensível que essa cirurgia só evoluiu nos últimos anos no que diz respeito à variabilidade de técnicas que visam proporcionar o rejuvenescimento do lábio superior com o mínimo de efeitos adversos, suprindo as expectativas das clientes que aderem ao processo.
Educação e inclusão: a função do profissional de apoio para a atuação com alunos com transtorno do Espectro Autista (TEA)
Authors: Milan Davi , da Silva Erica Dantas , Brandão Paula Paraguassu , Brito Evandro de Oliveira , Da Silva Fabio José Antonio , Corrêa Monique Machado , Lucena João Batista , Almeida Rosa Maria Ferreira dos Santos , De Menezes Adriana , Dos Santos Cristiane Leite 
Published: November 2022

O estudo em questão alude sobre a função do profissional de apoio, verificamos que o profissional de apoio, é o profissional que auxilia o professor de sala no seu cotidiano pedagógico juntamente com os indivíduos com deficiência em suas atividades, funções que perpassam aspectos basilares do bem-estar físico do educando, bem como atua nas questões escolares auxiliando-o no cumprimento das suas atividades e desenvolvimento físico, mental e social. Assim o objetivo do mesmo é analisar a função do profissional de apoio no que concerne o seu trabalho com alunos que possuem o transtorno do espectro autista - TEA. A metodologia do presente estudo molda-se por ser uma revisão bibliográfica, considerando que providenciamos na literatura científica, aclarações de diversos autores que pontuam sobre o assunto em pauta. Conclui-se, por conseguinte, do estudo realizado o quão importante se faz a atuação do profissional de apoio, a importancia de sua qualificação adequada para lidar com os educandos que possuem deficiência, uma vez que estará contribuindo, para a efetivação da inclusão da criança com TEA, atuando de forma conjunta com o docente da sala regular.
Critérios para elaboração de projetos, estudo de caso em promotorias do Estado do Amazonas
Authors: Neto João Bosco Ramos Batista , Pinheiro Erika Cristina Nogueira Marques 
Published: November 2022

A complexidade de cada projeto pode variar dependendo do objetivo que busca o projetista, quando pensamos em normas técnicas para iniciar a construção, antes precisamos saber sua necessidade. Quando pensamos em construir uma promotoria, diversos critérios peculiares de segurança devem ser adicionados por se tratar de um lugar perigoso, critérios os quais não são aplicados em construções residenciais, comerciais e etc. Ao iniciar o projeto, devemos pensar em diversas condições, tanto de sua localização quanto sua segurança, já que promotores por executarem as leis, podem acabar recebendo sofrendo retaliações, e por tal situação uma promotoria deve ter uma segurança maior que a maioria dos locais. Assim podemos observar que construir um edifício desses possui diversas regras e condições bem diferentes da maioria dos outros projetos, assim sendo necessário que o projetista conheça esse tipo de edificação para que assim possa atender suas necessidades. O objetivo do nosso estudo é de compreender como projetar uma promotoria e entender qual suas diferenças de outras construções, suas necessidades e sua função.