bluuebunny/crossref_metadata_2025_split huggingface dataset:
Planning decision alterations and container terminal efficiency
Authors: Weerasinghe Buddhi A. , Perera H. Niles , Kießner Phillip 
Published: February 2022

PurposeThis paper examines how the altering nature of planning decisions affects operational efficiency in seaport container terminals. The uncertainty and the role of the planner were investigated considering the dynamic integrated planning function of the quay to yard interface.Design/methodology/approachA system dynamics model has been built to illustrate the integrated dynamic environment. Data collection was conducted at a leading container terminal at a hub port. The model was simulated for different scenarios to derive findings.FindingsThe planner has been identified as the agent who makes alterations between the initial operational plan and the actual plan. The initial plan remains uncertain even when there is no impact from crane breakdowns, requiring a significant number of alterations to be made. The planner who had worked on the yard plan had altered (approximately 45%) the initial plan than the alterations done by the planner who had worked on the vessel plan. As a result, the feedback loop that is created by the remaining moves at each hourly operation influences the upcoming operation as much as crane breakdowns influence.Originality/value The uncertainty and the role of the planner were investigated considering the dynamic integrated planning function of the quay to yard interface. The findings of this study are significant since terminal efficiency is examined considering the quayside and landside as an integrated system.
Positive side effects of the Covid-19 pandemic on environmental sustainability: evidence from the quadrilateral security dialogue countries
Authors: Mishra Amritkant 
Published: February 2022

PurposeThe eruption of coronavirus disease 2019 (COVID-19) has pointedly subdued global economic growth and producing significant impact on environment. As a medicine or a treatment is yet available at mass level, social distancing and lockdown is expected the key way to avert it. Some outcome advocates that lockdown strategies considered to reduce air pollution by curtailing the carbon emission. Current investigation strives to affirm the impact of lockdown and social distancing policy due to covid-19 outbreak on environmental pollution in the QUAD nations.Design/methodology/approachTo calibrate the social movement of public, six indicators such residential mobility, transit mobility, workplace mobility, grocery and pharmacy mobility, retail and recreation mobility and park mobility have been deliberated. The data of human mobility have been gathered from the Google mobility database. To achieve the relevant objectives, current pragmatic analysis exerts a panel autoregressive distributed lag model (ARDL)-based framework using the pooled mean-group (PMG) estimator, proposed by Pesaran and Shin (1999), Pesaran and Smith (1995).FindingsThe outcome reveals that in the long-run public mobility change significantly impact the pollutants such as PM2.5 and nitrogen dioxide; however, it does not lead to any changes on ozone level. As per as short run outcome is concerned, the consequence unearths country wise heterogeneous impact of different indicators of public mobility on the air pollution.Research limitations/implicationsThe ultimate inferences of the above findings have been made merely on the basis of examination of QUAD economies; however, comprehensive studies can be performed by considering modern economies simultaneously. Additionally, finding could be constraint in terms of data; for instance, Google data used may not suitably signify real public mobility changes.Originality/valueA considerable amount of investigation explores the impact of covid-19 on environmental consequences by taking carbon emission as a relevant indicator of environmental pollution. Hence, the present pragmatic investigation attempts to advance the present discernment of the above subject in two inventive ways. Primarily, by investigating other components of environmental pollution such as nitrogen dioxide, PM2.5 and ozone, to reveal the impact of covid-19 outbreak on environmental pollution, as disregarded by the all preceding studies. Additionally, it makes a methodological contribution before integrating supplementary variables accompanying with ecological air pollution. Finally, the current research article provides an alternative and creative approach of modeling the impact of public mobility on environmental sustainability.
Space and place: a study of a specialized service desk
Authors: Bankston Sarah , German Elizabeth , Hebert Shelby , Laddusaw Sierra , Watts John , Weare William H. 
Published: February 2022

PurposeThis study examines the activities of a specialized service desk and provides guidance on conducting an analysis of the activities. The authors wanted to know what is essential in terms of expertise, staffing, technology, collections and space at a Maps and Geographic Information Systems (GIS) Service desk. The purpose of the study was to explore whether the provision of these services require a staffed service desk.Design/methodology/approachThe authors collected data using mixed methods, including observing space use, administering a survey and analyzing desk interactions.FindingsFindings suggest that while this service desk may have relatively little traffic, the interactions are time consuming and require a high degree of subject expertise. The data indicated that this service does not need to be delivered in this specific location; however, retaining the expertise and access to collections is vital. The authors recommend that formal assessment of services and space should be conducted prior to making significant changes in a service model.Originality/valueThis study investigates a specialized service desk which are not well-represented in the literature. Additionally, the variety of approaches used in this study could serve as a model for others for service desk assessment in general.
Seaweeds influence oyster microbiota and disease susceptibility
Authors: Dugeny Elyne , de Lorgeril Julien , Petton Bruno , Toulza Eve , Gueguen Yannick , Pernet Fabrice 
Published: February 2022

Abstract

A growing awareness of role that microbiota can play in mediating the effects of pathogens on hosts has given rise to the concept of the pathobiome. Recently, we demonstrated that the Pacific oyster mortality syndrome affecting Crassostrea gigas oysters is caused by infection with the Ostreid herpesvirus type 1 (OsHV‐1) followed by infection with multiple bacterial taxa.

Here we extend the concept of this pathobiome beyond the host species and its bacterial microbiota by investigating how seaweed living in association with oysters influences their response to the disease. We hypothesized that by their mere presence in the environment, different species of seaweeds can positively or negatively influence the risk of disease in oysters by shaping their bacterial microbiota and their immune response. Although seaweed and oysters do not have direct ecological interactions, they are connected by seawater and likely share microbes.

To test our hypothesis, oysters were acclimated with green, brown or red algae for 2 weeks and then challenged with OsHV‐1. We monitored host survival and pathogen proliferation and performed bacterial microbiota and transcriptome analyses.

We found that seaweeds can alter the bacterial microbiota of the host and its response to the disease. More particularly, green algae belonging to the genus Ulva spp. induced bacterial microbiota dysbiosis in oyster and modification of its transcriptional immune response leading to increased susceptibility to the disease.

This work provides a better understanding of a marine disease and highlights the importance of considering both macrobiotic and microbiotic interactions for conservation, management and exploitation of marine ecosystems and resources.
Does aid matter for FDI in ECOWAS: Investigating the infrastructure channel
Authors: Onye Kenneth , Bassey Godwin , Iriabije Alex , Effiom Lionel 
Published: February 2022

AbstractThis paper investigates whether and how aid targeted at specific sub‐categories of economic infrastructure could assist the economies of 14 Economic Community of West African States to attract higher foreign direct investment (FDI) inflow via improvement in infrastructure in water supply and sanitation, energy, transport and ICT. By relying on the three stage least squares estimation technique that is able to account for endogeneity among structural equations, and utilizing data spanning 2005–2018, we found quite interesting results. First, aid targeted at infrastructure indicates a strong positive effect on the countries’ infrastructure endowment. Second, there is robust evidence that aid promotes FDI, but not necessarily through the infrastructure channel. Targeted aid appears to exert a positive and direct knock‐on effect on FDI—apparently, because investors anticipate the positive effect that targeted aid is almost always inclined to produce on host countries’ infrastructure endowment. Finally, aid allocation by Development Assistance Committee donors seems to have been primarily merit‐based, followed by weaker evidence for “need”. The study recommends, inter alia, more need‐based aid allocation, particularly in economies where initial infrastructure endowment is minimal.
Recruitment of IL‐1β‐producing intermediate monocytes enhanced by C5a contributes to the development of malignant pleural effusion
Authors: Luo Lisha , Deng Shuanglinzi , Tang Wei , Hu Xinyue , Yin Feifei , Ge Huan , Tang Jiale , Liao Zhonghua , Li Xiaozhao , Feng Juntao 
Published: February 2022

AbstractBackgroundMonocytes are involved in tumor growth and metastasis, but the distribution of monocyte phenotypes and their role in the development of malignant pleural effusion (MPE) remains unknown.MethodsA total of 94 MPE patients (76 diagnosed with adenocarcinoma lung cancer and 18 with squamous cell lung cancer) and 102 volunteers for health examination in Xiangya Hospital from December 2016 to December 2019 were included in the study.ResultsThe distribution of monocyte subtypes identified by the expression of CD14 and CD16 were analyzed by flow cytometry. The proportion of CD14++CD16+ intermediate monocytes were significantly increased in pleural effusion of MPE patients. The complement system components were assayed by immunohistochemistry and ELISA, and higher expression of the classical and alternative pathways were detected in malignant pleural tissue. Transwell assay further revealed that C5a enhanced the infiltration of intermediate monocytes into the pleural cavity by promoting CCL2 production in pleural mesothelial cells (PMCs). In addition, C5a promoted the secretion of IL‐1β by intermediate monocytes. Furthermore, C5a activated in intermediate monocytes and IL‐1β released after C5a stimulation by monocytes promoted the proliferation, migration, adhesion, and epithelial‐to‐mesenchymal transition (EMT) of tumor cells, and attenuated tumor cell apoptosis.ConclusionsC5a, activated by the classical and alternative pathways of the complement system, not only mediated the infiltration of intermediate monocytes by enhancing CCL2 production in PMCs but also induced IL‐1β release from the recruited monocytes in MPE. The consequence of C5a activation and the subsequent IL‐1β overexpression in intermediate monocytes contributed to MPE progression.
AuraGain™ versus i‐gel™ for bronchoscopic intubation under continuous oxygenation: A randomised controlled trial
Authors: Svendsen Christine N. , Rosenstock Charlotte V. , Glargaard Gine L. , Strøm Camilla , Lange Kai H. W. , Lundstrøm Lars H. 
Published: February 2022

AbstractIntroductionAfter failed mask ventilation and tracheal intubation, guidelines issued by the Difficult Airway Society recommend placing a second generation supraglottic airway device to secure oxygenation. Ultimately, a secure airway can be obtained by tracheal intubation through the supraglottic airway device using a bronchoscope. In this randomised trial, we compared the AuraGain™ with the i‐gel™ as conduit for bronchoscopic intubation under continuous oxygenation performed by a group of anaesthesiologists with variable experience in a general population of patients.MethodWe randomised one hundred patients who were equally allocated to flexible bronchoscopic intubation through the i‐gel™ or the AuraGain™. In a random order, 25 anaesthesiologists each performed four intubations, two using the i‐gel™ and two using the AuraGain™. Our primary outcome was ‘total time for airway management’; i.e. total time from manually reaching the SAD to successful FBI confirmed at the end of the first inspiratory downstroke on the capnography curve.ResultsIn total, 87% (95% CI, 79%–92%) of the patients were successfully intubated through the allocated supraglottic airway device. There was no difference in total time for airway management between the i‐gel™ and the AuraGain™ (199 vs. 227 s, p = .076). However, there was a difference in time for placement of the i‐gel™, compared to the AuraGain™, (37 vs. 54 s, p < .001). There were nine failed intubations in the AuraGain™ group compared to four in the i‐gel™ group (p = .147).ConclusionWe found no difference in total time for airway management between using the i‐gel™ and using the AuraGain™.
Agglomeration bonus and endogenous group formation
Authors: Bareille François , Zavalloni Matteo , Viaggi Davide 
Published: February 2022

AbstractAgglomeration bonus schemes are envisioned to incentivize the connectivity of habitat conservation across landowners. Assuming full cooperation among landowners at the landscape scale, the bulk of the literature theoretically finds that agglomeration bonus schemes are more cost effective in achieving biodiversity conservation than spatially homogenous payments. However, it may be rational for landowners not to cooperate all together but, rather, to cooperate within smaller groups. Here, we analyze the cost effectiveness of agglomeration bonus schemes when such partial cooperation is allowed, that is, when cooperation is endogenously chosen. We introduce a spatially explicit ecological‐economic model within a coalition formation game to assess how landowners form stable coalition structures and how this affects biodiversity conservation under a wide range of (i) degrees of spatial cost autocorrelation, (ii) bonuses and flat‐rate payments, (iii) species dispersal rates, and (iv) coordination costs. We find that agglomeration bonus schemes are more cost effective than homogenous payments only for low public expenditures. This condition is not identified if full cooperation is assumed. We find, however, that full cooperation never emerges and hence that such an assumption leads to an overestimation of the cost effectiveness of agglomeration bonus schemes. Moreover, we find that the cost effectiveness of agglomeration bonus schemes increases when the spatial cost autocorrelation and species dispersal rate decrease. Finally, coordination costs do not affect the cost effectiveness of the agglomeration bonus scheme but they have implications for its design because of their impact on coalition formation.
Melatonin regulates trophoblast pyroptosis, invasion and migration in preeclampsia by inhibiting HtrA1 transcription through the microRNA‐520c‐3p/SETD7 axis
Authors: Liu Zhaochun , Chen Bin , Chang Jing , Feng Lulu , Zhao Xia 
Published: February 2022

AbstractObjectiveMelatonin has an inhibitory effect on preeclampsia (PE). This study was launched to explore the way that melatonin regulated trophoblast migration, invasion, and pyroptosis in PE and to provide new ideas for the diagnosis and treatment of PE.MethodsExpression levels of melatonin receptors (MT1 and MT2), microRNA (miR)‐520c‐3p, SETD7, and HtrA1 in placental tissues and HTR8/SVneo cells were measured by RT‐qPCR and Western blot. Scratch, Transwell, and Western blot assays were performed to detect migration, invasion, and pyroptosis of hypoxia/reoxygenation (H/R)‐treated HTR8/SVneo cells. Dual‐luciferase reporter assay was utilized to verify the targeting relationship between miR‐520c‐3p and SETD7. ChIP experiment was conducted to detect the enrichment of H3K4me3 and SETD7 in HtrA1 promoter.ResultsLow expression of MT1, MT2, and miR‐520c‐3p and high expression of SETD7 and HtrA1 were observed in the placental tissues of PE patients and H/R‐treated HTR8/Svneo cells. A high concentration of melatonin promoted migration and invasion and inhibited pyroptosis of PE cell models. Knockdown of miR‐520c‐3p, overexpression of SETD7, or overexpression of HtrA1 impaired migration and invasion and accelerated pyroptosis of H/R‐treated HTR8/SVneo cells, but these outcomes could be reversed by treatment with 1000 μM melatonin. miR‐520c‐3p targeted SETD7 which promoted histone methylation in the promoter region of HtrA1.ConclusionMelatonin may inhibit HtrA1 transcription through the miR‐520c‐3p/SETD7 axis to promote trophoblast invasion and migration and reduce trophoblast pyroptosis in PE.
Staff mental health while providing care to people with intellectual disability during the COVID‐19 pandemic
Authors: Sheerin Fintan , Allen Andrew P. , Fallon Marianne , McCallion Philip , McCarron Mary , Mulryan Niamh , Chen Yaohua 
Published: February 2022

AbstractBackgroundThe COVID‐19 pandemic has placed enormous strain on health systems around the world, undermining the mental health and wellbeing of healthcare workers. Supporting people with intellectual disabilities may be particularly challenging for workers, as some people with intellectual disabilities may have a limited understanding of the pandemic, and find it challenging to adhere to the restrictions imposed by public health guidelines such as social distancing, lockdowns and change in usual routine and activities. In addition, many people with intellectual disabilities have increased vulnerability to more negative effects of COVID‐19, with significantly higher mortality rates. Although there is emerging research on the mental health of healthcare staff during this time, there has been little specific work on the mental health of staff working with people with intellectual disability, particularly a lack of qualitative research.MethodsThe current study employed semi‐structured interviews with 13 healthcare workers (12 women and 1 man) who were working with people with intellectual disability during the COVID‐19 pandemic. The interview data were analysed using thematic content analysis.FindingsThe participants spoke in depth about the challenges of the working environment, the impact of providing care during the pandemic on staff mental health, supporting staff mental health and wellbeing and learning for the future.ConclusionsSystematic efforts are required to protect the mental health of this staff cohort, as well as encouraging resilience and successful coping among staff themselves.
A randomized controlled trial of 6‐month dental home visits on 24‐month caries incidence in preschool children
Authors: Babar Muneer Gohar , Andiesta Niekla Survia , Bilal Sobia , Yusof Zamros Yuzadi Mohd , Doss Jennifer Geraldine , Pau Allan 
Published: February 2022

AbstractObjectivesThis paper reports on the effect of 6‐month dental home visits compared to no dental home visits on 24‐month caries incidence in 5‐ to 6‐year‐olds.Methods5‐ to 6‐year‐olds attending kindergartens were randomized to receive either 6‐month dental home visits and education leaflets (Intervention group) or education leaflets alone (Control group) over 24 months. To detect a 15% difference in caries incidence with a significance level of 5% and power of 80%, 88 children were calculated to be needed in the Intervention group and 88 in the Control. Baseline clinical data included oral examinations at the kindergartens. Follow‐up visits were made on the 6th, 12th and 18th month. At the end of the 24 months, both the Intervention and Control groups were visited for oral examinations. The primary outcome was caries incidence, measured by the number and proportion of children who developed new caries in the primary molars after 24 months. The secondary outcome was the number of primary molars that developed new caries (d‐pms). Frequency distributions of participants by baseline socio‐demographic characteristics and caries experience were calculated. The chi‐square test was used to test differences between the caries experience in the Intervention and Control groups. The t test was used to compare the mean number of primary molars developing new caries between the Intervention Group and the Control Group. The number of children needed to treat (NNT) was also calculated.ResultsAt the 24‐month follow‐up, 19 (14.4%) developed new caries in the Intervention Group, compared to 60 (60.0%) in the Control Group (p = .001). On average, 0.2 (95% CI = 0.1–0.3) tooth per child in the Intervention Group was observed to have developed new caries compared to 1.1 (95% CI = 0.8–1.3) tooth per child in the Control Group (p = .001). The number of children needed to treat (NNT) to prevent one child from developing new caries was 2.2.ConclusionsThe present study has demonstrated that 6‐month home visits to families of 5‐ to 6‐year‐olds are effective in caries prevention in 5‐ to 6‐year‐olds of low‐income families in a middle‐income country where access to health services, including oral health promotion services, is limited.
Post‐socialist geopolitical uncertainties: Researching memories of childhood with ‘child as method’
Authors: Burman Erica , Millei Zsuzsa 
Published: February 2022

AbstractThis article engages continuing discussions in childhood studies on (re)inserting the study of childhood into wider socio‐political matrices of power and practices. We present as a potent analytical strategy to do this work ‘child as method’, developed by one of the authors. After describing ‘child as method’, we draw on the Recollect/Reconnect project, in which scholars and artists who grew up during the last decades of the Cold War recalled their childhood memories. We focus on ‘the child’ and ‘childhood’ as a position of geopolitical address, formulated by narrators to the reader as revealing emergent post‐socialist subjectivities and conditions.