bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Plasma Metanephrines in Predicting Cardiovascular and Cerebrovascular Events in Patients With Essential Hypertension
Authors: Wang Hui-min , Yin Wen-jie , Ke Bing-bing , Tan Xin , Wang Xue , Wang Yuan , Zhang Yan-bo , Li Si-jin , Du Jie 
Published: October 2022

Abstract

Background
To investigate the role of plasma metanephrines (MN) and normetanephrines (NMN), in predicting cardiovascular events in essential hypertensive patients.

Methods
This was a retrospective analysis of 688 hospitalized patients diagnosed with essential hypertension at the Beijing Anzhen hospital from October 2016 to August 2018, with a median (interquartile range) follow-up time of 24 (20–29) months. The primary endpoint was defined as all-cause death and/or readmission for cardiovascular or cerebrovascular events. Patients were divided into event (n = 57) and nonevent (n = 631) groups. High-performance liquid chromatography–tandem mass spectrometry was used to determine plasma MN and NMN levels. According to the cutoff value of plasma NMN from receiver operating characteristic analysis, patients were further divided into NMN ≤125.75 ng/l and NMN &gt;125.75 ng/l groups. The effects of NMN on the prognosis of hypertensive patients were evaluated using Kaplan–Meier curves and multivariate Cox regression analysis.

Results
The plasma NMN levels of the event group were higher than those of the nonevent group [110.0 (74.0–135.0) vs. 88.5 (62.0–119.5) ng/l, P = 0.004]. The incidence of the primary endpoint event in NMN ≤125.75 ng/l and NMN &gt;125.75 ng/l groups was 6.0% and 15.8%, respectively. Kaplan–Meier analysis showed that patients with higher baseline NMN levels were more likely to experience adverse events (P &lt; 0.001). Cox regression analysis showed that patients in NMN &gt;125.75 ng/l group had over twofold higher risk of the primary endpoint event than those in NMN ≤125.75 ng/l group (HR = 2.11, 95% CI 1.15–3.84, P = 0.015).

Conclusions
Elevated plasma NMN levels are associated with higher risk of cardiovascular and cerebrovascular events in patients with essential hypertension.
The Correlation Between Obesity Phenotypes and High Normal Blood Pressure in Fuzhou Community Residents
Authors: Shi Lu-qian , Cai Ying-ying , Xu Xing-yan , Li Qiao-wei , Chen Rui-xin , Sun Yu , Shen Qian , Wei Dong-hong , Lin Shao-wei , Wu Si-ying 
Published: October 2022

Abstract

Background
To explore the correlation between obesity phenotypes and high normal blood pressure (BP) among residents residing in Fuzhou communities.

Methods
A cross-sectional study was conducted and on-site questionnaire survey, physical examinations and laboratory tests were carried out on the residents aged over 18 years in communities of Fuzhou city from 2018 to 2019, in which 900 people with normal BP and 1,006 people with high normal BP were included for analysis. Univariate analysis and multivariate logistic regression model were utilized to analyze the relationship between obesity phenotypes and high normal BP. Receiver operating characteristic (ROC) curve was used to analyze the predictive power of various obesity phenotypes for high normal BP in different genders.

Results
The rates of overweight and obesity, abdominal obesity (28.4% vs. 16.0%, P &lt; 0.001), and abnormal waist-to-height ratio (61.6% vs. 41.1%, P &lt; 0.001) were higher in the high normal BP group than those in normal BP group. Multivariate logistic regression analysis showed that high normal BP was positively correlated with body mass index, waist circumference, and waist-to-height ratio. Furthermore, overweight (OR, 95% CI: 1.896, 1.390–2.587), obesity (2.489, 1.427–4.342), abdominal obesity (1.598, 1.152–2.215), and abnormal waist-to-height ratio (2.110, 1.579–2.821) were risk factors of high normal BP among females while abdominal obesity (1.649, 1.021–2.661) and abnormal waist-to-height ratio (1.504, 1.044–2.165) were risk factors of high normal BP among males. The ROC area under the curve was over 0.6 for all obesity types.

Conclusions
Overweight, obesity, abdominal obesity, and abnormal waist-to-height ratio are risk factors of high normal BP.
Consuming Ali Abdul: conditional acceptance in the context of Korean multiculturalism
Authors: Kim Seonah , Lee Jeehyun Jenny , Swan Anna Lee 
Published: October 2022

Abstract
This article examines the representation of Ali Abdul, the Pakistani character in the global Netflix hit Squid Game. While Ali has been celebrated for increasing South Asian representation in Korean media, we contextualize his portrayal through the lens of Korean multiculturalism. In doing so, we consider how the representation of Ali reflects the conditional acceptance of migrant men established by state-led Korean multicultural policies and politics. Through a close reading of the conditions that humanize Ali as both worthy of sympathy and unequal to his Korean counterparts, we argue that Ali’s acceptance hinges upon his relation to Korean protagonists in ways that further a vision of ethnocentric nation-building through the racialization of dark-skinned masculinity.
Anglican Evangelicalism
Authors: Carter Grayson 
Published: October 2022

Abstract
his chapter examines the rise and progress of Evangelicalism in the Church of England during the eighteenth century. While the movement began in relative isolation in Wales, it soon spread geographically, its teachings finding a receptive audience among many in the Church. Early on, Evangelicals faced numerous challenges, not least in overcoming opposition to their doctrines, evangelistic aims, and disregard of church order. By the end of the century, however, the influence of Evangelicalism had extended into many parts of the Church, the wider society, and even foreign lands, attracting men and women of abundant talent, energy, and spiritual commitment, and transforming the nature of Anglicanism in England and beyond. Especially noteworthy was the leading role the early Evangelicals played in the campaign for abolition, the formation of numerous voluntary societies, the support of women’s spirituality, and enacting various social reforms.
Itinerancy
Authors: Hall Timothy D. 
Published: October 2022

Abstract
This chapter discusses how eighteenth-century evangelical leaders adapted the practice of itinerant preaching to make it a primary method for spreading their message of New Birth through repentance and faith in Jesus. Itinerancy was a controversial category of preaching, provoking concerns about social disruption and ecclesiastical authority within local communities as well as questions concerning the authenticity of such preachers themselves. Nevertheless, itinerancy was readily adaptable to the more open, mobile, commercial society that the eighteenth-century British Empire was becoming. The Anglican itinerant George Whitefield and his associates learned to use it in concert with techniques in print and advertising to become a very powerful means of spreading their message. The growing practice of itinerancy in turn transformed the religious landscape of the empire into one more fluid, open, interdenominational, and egalitarian than had obtained under the parochial system that had served to structure both ecclesial and social order.
John Erskine and Transatlantic Correspondent Networks
Authors: Yeager Jonathan 
Published: October 2022

Abstract
This chapter examines eighteenth-century evangelical transatlantic letter writing as a means of communication. Early evangelicals developed networks in the 1730s and 1740s, at first as a way of exchanging information about the revivals that were taking place at this time throughout America, Britain, and Western Europe. After this period of revival diminished, evangelicals on both sides of the Atlantic continued to share news of the state of religion in their respective communities. Using the evangelical Scottish minister John Erskine as a case study helps us understand the nature of these networks, including the structure and content of their letters, as well as their greatest concerns. From examining Erskine and other eighteenth-century evangelicals, we learn that leaders of this movement were predominantly anti-Catholic and that Reformed ministers in particular used their letters and published works to combat perceived threats to their understanding of Protestantism, including views promulgated by those with Arminian, Arian, Socinian, and Universalist views.
Ann Bolton and Early Evangelical Women
Authors: Aalders Cynthia 
Published: October 2022

Abstract
This chapter explores the agency and religious activism of early evangelical women through the life-writings of one British Methodist woman, Ann Bolton. Considerable scholarly attention has been given to those rare opportunities when eighteenth-century religious women surmounted gendered barriers to use their voices in the pulpit and print, as well as their more usual influence in the domestic world of home and family. Aalders argues that critical attention to women’s life-writings reveals a far broader range of women’s religious activities—activities that often took place at the intersection of public and private worlds and included both teaching and evangelism. While traditional interpretations of the Bible, together with social mores that favored women’s silence and humility, presented tensions for early evangelical women who wished to take an active role in ministry, they were able to overcome such hinderances by claims to a divine calling. Ann Bolton’s substantial archive—which includes a diary kept for almost thirty years and hundreds of letters—complicates and enriches our understanding of the scope of eighteenth-century women’s religious worlds.
Hymnody
Authors: Noll Mark 
Published: October 2022

Abstract
Landmark hymn collections by George Whitefield (1753) and especially John Wesley (1780) broadcast the key emphases of the eighteenth-century evangelical movement. John’s brother Charles led in creating a new hymnody for the awakenings’ new sensibilities. Antecedents of evangelical hymnody included the High-Church Anglican societies of the late seventeenth century where psalm-singing played a large part. Continental hymnody, as developed by Lutherans, pietistic movements, and especially the Moravians, contributed more in both expressive content and creative forms. Puritanism was a third historical influence, mostly through the hymns of the Dissenter Isaac Watts who liberated English hymnody from exclusive psalmody. Fervent singing of newly composed hymns or the hymns of Isaac Watts marked evangelical movements throughout the Atlantic region: Methodist led by Charles Wesley in England; Welsh revivalists, among whom William Williams Pantycelyn played the key role; and Samuel Davies who pioneered the use of hymns and hymn-writing in the colonies. Evangelical hymnody linked evangelicals who were otherwise much divided. It innovated with an intense focus on Christ as redeemer, creative allusions to Scripture, and many new meters and rhyme schemes. Black evangelicals participated fully in the era’s new hymnody, as did women hymn-writers like Ann Steele of England and Ann Griffiths of Wales.
English Congregationalism
Authors: Strivens Robert 
Published: October 2022

Abstract
This chapter examines the English Congregationalism of the first half of the eighteenth century, with particular reference to Isaac Watts and Philip Doddridge. It focuses on issues concerning Trinitarian belief, attitudes to revival, and denominational identity. It argues that in, each of these areas, early eighteenth-century Congregationalism experienced considerable fluidity within a wider Dissent. Watts and Doddridge sought in this context to promote a vision for the spiritual renewal of Dissenting congregations based on a more flexible theological approach coupled with a church-based revival of spirituality influenced by aspects of German pietism.
Le suivi de l’extrême prématuré après le congé des soins intensifs néonatals
Authors: Hendson Leonora , Church Paige T , Banihani Rudaina 
Published: October 2022

Résumé
La survie des extrêmes prématurés (moins de 28 semaines d’âge gestationnel) s’est améliorée au fil du temps. Bon nombre s’en sortent bien et ont une bonne qualité de vie. Ils demeurent toutefois vulnérables à des problèmes de santé, y compris des difficultés neurosensorielles et neurodéveloppementales, que les médecins de première ligne, les pédiatres et les cliniques spécialisées doivent surveiller. Le présent document de principes passe en revue les conséquences médicales et neurodéveloppementales potentielles pour les extrêmes prématurés dans les deux ans suivant leur congé et fournit des stratégies de counseling, de dépistage précoce et d’intervention. Parce qu’ils sont tous liés à l’extrême prématurité, la dysplasie bronchopulmonaire ou les troubles respiratoires, les problèmes d’alimentation et de croissance, le développement neurosensoriel (vision et audition), la paralysie cérébrale et le trouble du spectre de l’autisme doivent faire rapidement l’objet d’une évaluation. Pour évaluer la croissance et le développement, il faut corriger l’âge chronologique en fonction de l’âge gestationnel jusqu’à 36 mois de vie. Par ailleurs, l’attention au bien-être émotionnel des parents et des proches fait partie intégrante des soins de qualité de l’extrême prématuré.
La négligence en matière de soins médicaux : travailler auprès des enfants, des adolescents et des familles
Authors: Ward Michelle G K , Baird Burke 
Published: October 2022

Résumé
Les soins de santé sont un droit fondamental pour tous les enfants. Lorsque les besoins de santé de l’enfant ne sont pas respectés, quelle qu’en soit la raison, les professionnels de la santé doivent réfléchir aux obstacles en cause et aux processus nécessaires pour trouver des solutions. Des obstacles sociaux, économiques ou autres peuvent empêcher les parents d’accéder aux soins pour leur enfant. Il arrive que les avis, les priorités ou les valeurs des professionnels de la santé de l’enfant divergent de ceux des parents, ce qui compromet les soins à l’enfant. Dans certains cas, l’abstention des personnes qui s’occupent de l’enfant à assurer les soins nécessaires peut être considérée comme de la négligence en matière de soins médicaux. Des habiletés et des connaissances particulières peuvent aider les professionnels de la santé à éviter de telles situations et à collaborer avec efficacité avec la famille lorsque ces situations se produisent. Le présent document de principes offre une approche que peuvent utiliser les professionnels de la santé pour promouvoir l’intérêt supérieur, le bien-être et la sécurité des enfants ou des adolescents vulnérables à la négligence en matière de soins médicaux.
What Drives the Size and Value Factors?
Authors: Li Jiacui 
Published: October 2022

Abstract
I find that approximately 30% of price fluctuations in the Fama-French size and value factors are nonfundamental price pressures driven by correlated fund flows, which generate price movements that revert over time. Is this really demand-based price pressure? I show that the price effects happen exclusively in periods when mutual funds place trades, a fact that is difficult to explain using traditional mechanisms such as unobserved investor preference changes. The estimated price elasticity is also consistent with other studies. Overall, my findings show that a sizable fraction of size and value factor movements do not represent economic risk. (JEL G10, G12, G23, G40)
Open Editors: A dataset of scholarly journals’ editorial board positions
Authors: Nishikawa-Pacher Andreas , Heck Tamara , Schoch Kerstin 
Published: October 2022

AbstractEditormetrics analyses the role of editors of academic journals and their impact on the scientific publication system. Such analyses would best rely on open, structured, and machine-readable data about editors and editorial boards, which still remains rare. To address this shortcoming, the project Open Editors collects data about academic journal editors on a large scale and structures them into a single dataset. It does so by scraping the websites of 7,352 journals from 26 publishers (including predatory ones), thereby structuring publicly available information (names, affiliations, editorial roles, ORCID etc.) about 594,580 researchers. The dataset shows that journals and publishers are immensely heterogeneous in terms of editorial board sizes, regional diversity, and editorial role labels. All codes and data are made available at Zenodo, while the result is browsable at a dedicated website (https://openeditors.ooir.org). This dataset carries implications for both practical purposes of research evaluation and for meta-scientific investigations into the landscape of scholarly publications, and allows for critical inquiries regarding the representation of diversity and inclusivity across academia.
Can behavior change techniques be delivered via short text messages?
Authors: Doğru Onur Cem , Webb Thomas L , Norman Paul 
Published: October 2022

Abstract
Despite significant advancements in behavioral science it is unclear whether behavior change techniques (or BCTs) can be delivered to large numbers of people in a cost-effective and reliable way. The current study investigated whether it is possible to reliably deliver BCTs using short text messages. Short text messages were designed to deliver each of the 93 BCTs specified in the BCT taxonomy v1. Following initial coding and refinement by the team, a Delphi study with a panel of 15 experts coded which BCT each short text message was designed to deliver and also rated whether they were likely to be understood by recipients and easily converted to target different behaviors. After two iterations, the experts correctly assigned 66 of the 93 messages to the BCT that they were designed to deliver and indicated that these messages were likely to be easy to apply to a range of behaviors and understood by recipients. Experts were not able to identify which BCT 27 of the messages were designed to deliver and it was notable that some clusters of BCTs (e.g., “Goals and planning”) were easier to deliver via short text messages than other clusters (e.g., “Scheduled consequences”). The findings suggest that short text messages can be a reliable way to deliver many, but not all, BCTs. The implications of the current study are discussed with respect to the delivery of specific BCTs and clusters of the taxonomy, as well as the need to test the acceptability of interventions delivered via short messages and the impact of messages on behavior.
Assessment of potential in vitro toxicity of Cissus sicyoides L. and Wedelia paludosa DC. leaves water extracts
Authors: Ponath Amanda Schu , Volz Débora Rech , Suyenaga Edna Sayuri , Ziulkoski Ana Luíza , Perassolo Magda Susana 
Published: October 2022

Abstract
Medicinal plants have been employed as an alternative method to treat diabetes. One is Cissus sicyoides, a plant from the Amazon region (Northern Brazil), which is morphologically similar to Wedelia paludosa, a plant easily found in Southern Brazil. Thus, this study aimed to assess the potential toxicity of C. sicyoides and W. paludosa’s leaves water extracts. Through phytochemical screening, phenolic compounds and alkaloids were observed in both species and coumarins only W. paludosa’s aqueous extract. Phenolic compounds were quantified in both extracts and C. sicyoides presented 1.36 ± 0.04 mg/pyrogalic acid equivalent (PAE), whereas W. paludosa presented 3.27 ± 0.07 mg/PAE. Total antioxidant power was measured by the ferric reduction assay. Cissus sicyoides exhibited total antioxidant activity of 748.0 ± 104.5 μM and W. paludosa, 1971.5 ± 141.0 μM. Cissus sicyoides showed an inhibition rate for the alpha-glucosidases enzyme assay of 55.2 ± 1.7% and W. paludosa, 85.8 ± 9.7%. The formation of reactive oxygen species was evaluated by the DCFH-DA method, its formation being higher in W. paludosa’s water extracts than in C. sicyoides. Cell viability was evaluated by the Sulforhodamine B and MTT assays. Wedelia paludosa’s extracts’ exposure presented a cell viability close to positive control starting from 2 mg/mL to 30 mg/mL, whereas C. sicyoides demonstrated statistical significant low viability at the highest concentration when compared with the negative control. Moreover, cell death mechanism was investigated, having W. paludosa’s extract indicated death by necrosis. The results suggest low toxicity for C. sicyoides’ extract and high toxicity for W. paludosa’s extract.
Muscle injury induces a transient senescence‐like state that is required for myofiber growth during muscle regeneration
Authors: Young Laura V. , Wakelin Griffen , Cameron Alasdair W. R. , Springer Stevan A. , Ross Joel P. , Wolters Grant , Murphy J. Patrick , Arsenault Michel G. , Ng Sean , Collao Nicolás , De Lisio Michael , Ljubicic Vladimir , Johnston Adam P. W. 
Published: October 2022

AbstractCellular senescence is the irreversible arrest of normally dividing cells and is driven by the cell cycle inhibitors Cdkn2a, Cdkn1a, and Trp53. Senescent cells are implicated in chronic diseases and tissue repair through their increased secretion of pro‐inflammatory factors known as the senescence‐associated secretory phenotype (SASP). Here, we use spatial transcriptomics and single‐cell RNA sequencing (scRNAseq) to demonstrate that cells displaying senescent characteristics are “transiently” present within regenerating skeletal muscle and within the muscles of D2‐mdx mice, a model of Muscular Dystrophy. Following injury, multiple cell types including macrophages and fibrog–adipogenic progenitors (FAPs) upregulate senescent features such as senescence pathway genes, SASP factors, and senescence‐associated beta‐gal (SA‐β‐gal) activity. Importantly, when these cells were removed with ABT‐263, a senolytic compound, satellite cells are reduced, and muscle fibers were impaired in growth and myonuclear accretion. These results highlight that an “acute” senescent phenotype facilitates regeneration similar to skin and neonatal myocardium.