bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGEMBANGAN LEMBAR KEGIATAN PESERTA DIDIK (LKPD) MENGGUNAKAN METODE PQ4R
Authors: Nimah Azimatun , M.Ak. Rochmawati S.Pd. 
Published: June 2022

Proses pembelajaran yang berlangsung dengan menggunakan LKPD bermetode PQ4R diketahui dapat meningkatkan kemampuan memahami peserta didik dengan langkah-langkah PQ4R untuk menciptakan proses membaca yang efektif. Materi perbedaan saldo kas dan saldo bank serta rekonsiliasi bank pada LKPD ini berupa konsep yang disajikan dalam bentuk tulisan dan angka, sehingga menekankan peserta didik untuk melakukan aktivitas membaca dalam memahami konsep dari setiap materi. Peranan LKPD PQ4R dapat menciptakan kegiatan pembelajaran yang lebih terencana dengan baik, mandiri, dan tuntas. Dengan begitu kebutuhan kompetensi pendidikan terpenuhi. Tujuan dilaksanakannya penelitian ini adalah untuk menghasilkan suatu bahan ajar berupa LKPD menggunakan metode PQ4R pada mata pelajaran akuntansi keuangan. Kurang lengkapnya bahan ajar yang digunakan serta tidak adanya bahan ajar pendukur dari bahan ajar utama pada pembelajaran akuntansi keuangan di SMK Negeri 1 Duduk Sampeyan, untuk itu dikembangkan bahan ajar berupa LKPD Akuntansi Keuangan kelas XI pada materi perbedaan saldo kas dan saldo bank serta rekonsiliasi bank menggunakan metode PQ4R. Penelitian ini adalah jenis penelitian pengembangan (RD) dengan model 4D menurut Thiagarajan yang meliputi empat tahap pengembangan yaitu pendefinisian, perancangan, pengembangan, dan penyebaran. Instrumen yang digunakan adalah lembar telaah ahli, lembar validasi ahli dan angket respon peserta didik. Hasil penelitian berupa: 1) Pengembangan Lembar Kegiatan Peserta Didik (LKPD) menggunakan metode PQ4R, 2) Kelayakan Lembar Kegiatan Peserta Didik terdiri atas kelayakan isi, penyajian, bahasa dan kegrafikan, memperoleh hasil rata-rata keseluruhan sebesar 81,95%, dengan kategori sangat layak, 3) Respon peserta didik memperoleh hasil rata-rata keseluruhan sebesar 97,33%, dengan kategori sangat baik. Kata kunci: LKPD, Metode PQ4R, Akuntansi Keuangan
Hopf bifurcation analysis of a fractional order Holling-Tanner predator-prey model with time delay
Authors: Çelik Canan , Değerli Kübra 
Published: June 2022

We study a fractional-order delayed predator-prey model with Holling–Tanner-type functional response. Mainly, by choosing the delay time \(\tau \) as the bifurcation parameter, we show that Hopf bifurcation can occur as the delay time \(\tau \) passes some critical values. The local stability of a positive equilibrium and the existence of the Hopf bifurcations are established, and numerical simulations for justifying the theoretical analysis are also presented.
doi:https://doi.org/10.1017/S1446181122000025
Mobile Technology Use and Acceptability of mHealth for HIV Prevention Among Men Who Have Sex With Men in Malaysia
Authors: Maviglia Francesca , Shrestha Roman , Altice Frederick L , DiDomizio Libby , Khati Antoine , Mistler Colleen , Azwa Iskandar , Kamarulzaman Adeeba , Halim Mohd Akbar , Wickersham Jeffrey A 
Published: June 2022

Background
The growth in mobile technology access, utilization, and services holds great promise for facilitating HIV prevention efforts in Malaysia. Despite these promising trends, there is a dearth of evidence on the use of mobile health (mHealth) platforms to address the HIV prevention needs of Malaysian men who have sex with men (MSM).

Objective
The goal of this study was to gain insights into (1) the access and utilization of communication technology (eg, landline phone, internet, and cell phone), (2) the acceptability of mHealth-based interventions for HIV prevention services, and (3) preferences regarding the format and frequency of mHealth interventions among Malaysian MSM.

Methods
A cross-sectional survey of 376 Malaysian MSM was conducted between July 2018 and March 2020. Participants were recruited using respondent-driven sampling in the Greater Kuala Lumpur region, Malaysia. Participants completed a self-administered assessment of participant demographics, HIV risk-related behaviors, access to and frequency of the use of communication technology, and the acceptability of mHealth for HIV prevention.

Results
Almost all participants owned or had access to a smartphone with internet access (97.9%) and accessed the internet daily (99.2%), mainly on a smartphone (88.8%). Using a 5-point scale, participants on average used smartphones primarily for social networking (mean 4.5, SD 0.8), followed by sending or receiving emails (mean 4.0, SD 1.0) and searching for health-related information (mean 3.5, SD 0.9). Further, the results indicated the high acceptance of mHealth for HIV prevention, that is, receiving HIV prevention information (91.8%), receiving reminders to take medications (89.4%), tracking sexual activity (81.4%), tracking drug use (74.7%), and monitoring drug cravings (74.5%), with the most preferred method being the smartphone app for all activities.

Conclusions
The findings from this study provide support for developing and deploying mHealth strategies for HIV prevention in MSM by using a smartphone app, which are crucial for a key population with suboptimal engagement in HIV prevention and treatment.

Conflicts of Interest
None declared.
Cytotoxic effects of parijoto (Medinilla speciosa Reinw. Ex. Bl.) methanol extract combined with cisplatin on WiDr colon cancer cells through apoptosis induction
Authors: Artanti Anif Nur , Prihapsara Fea , Susanto Ranita Kumalasari 
Published: June 2022

Parijoto (Medinilla speciosa Reinw. Ex. Bl.) is a medicinal plant with cytotoxic effects on cancer cells in vitro. As only a limited number of studies have reported the effect of parijoto on colon cancer cells, this study initially aimed to measure the total flavonoid levels and potential cytotoxic effects of parijoto methanol extract (PME) through cell viability assays and expression of the apoptotic protein on WiDr colon cancer cells as a model. PME cytotoxic activity was determined by conducting a cytotoxicity test on WiDr colon cancer cells using the MTT assay. The synergistic cytotoxic effects of the PME and cisplatin were tested to obtain the combination index (CI) value. Apoptosis was analyzed by flow cytometry, and the apoptotic protein expression was observed by immunocytochemical tests. Furthermore, quercetin as a major flavonoid in PME was measured using a UV–Vis spectrophotometer. The results showed that PME had a moderate cytotoxic activity with an IC50 of 198.64±1.6 µg/mL, whereas the IC50 of cisplatin was 2.34±0.7 µg/mL. The PME with cisplatin combination test showed a strong synergistic effect with a CI value of <1 (0.1‐0.4). The combination showed increased apoptosis properties compared to PME treatment alone. In addition, immunocytochemistry showed that PME alone or in combination with cisplatin increased the pro‐apoptosis proteins (p53 and caspase‐9) and suppressed Bcl‐2 expression. Moreover, the cell viability value increased as the PME concentration decreased. The administration of PME led to changes in cell morphology, lower cell density, and a decreasing number of living cells. Therefore, the combination of PME and cisplatin had a strong synergistic effect in inducing apoptosis.
The gut microbiome composition is altered in long-standing type 1 diabetes and associates with glycemic control and disease-related complications
Authors: Heck Julia IP van , Gacesa Ranko , Stienstra Rinke , Fu Jingyuan , Zhernakova Alexandra , Harmsen Hermie JM , Weersma Rinse K , Joosten Leo AB , Tack Cees J 
Published: June 2022

<p> </p>
<p><em>Objective:</em> People with type 1 diabetes are at risk of developing micro- and macrovascular complications. Little is known about the gut microbiome in long-standing type 1 diabetes. We explored differences in the gut microbiome of participants with type 1 diabetes compared to healthy controls and associated the gut microbiome with diabetes-related complications.</p>
<p><em>Research Design and Methods:</em> Microbiome data of 238 participants with type 1 diabetes with an average disease duration of 28 (±15) years were compared to 2937 age-, sex- and BMI-matched individuals. Clinical characteristics and fecal samples were collected and metagenomic shotgun sequencing was performed. Microbial taxonomy was associated with type 1 diabetes–related characteristics and vascular complications.</p>
<p><em>Results:</em> No significant difference in the α-diversity of the gut microbiome was found between participants with type 1 diabetes and healthy controls. However, 43 bacterial taxa were significantly depleted in type 1 diabetes, while 37 bacterial taxa were significantly enriched. HbA1c and disease duration explained a significant part of variation in the gut microbiome (R2>0.008, FDR<0.05), and HbA1c was significantly associated with the abundance of several microbial species. Additionally, both micro- and macrovascular complications explained a significant part of variation in the gut microbiome (R2>0.0075, FDR<0.05). Nephropathy was strongly associated with several microbial species. Macrovascular complications displayed similar associations to nephropathy.</p>
<p><em>Conclusion:</em> Our data show that the gut microbiome is altered in people with (long-standing) type 1 diabetes and is associated to glycemic control and diabetes-related complications. Due to the cross-sectional design, the causality of these relationships remains to be determined.</p>
A palavra cão não morde
Authors: Valverde Antonio José Romera 
Published: June 2022

Se o tempo presente se mostra fragmentado e sob fortes indícios de retorno à barbárie, - identificado por práticas e discursos políticos autoritários, em tendência de se tornarem hegemônicos -, o ensaio procura interpelar o estatuto contraditório da palavra no campo da política, através de uma sondagem lúdica. A exploração da matéria gravita em torno de uma página de Marat, de 1774, republicada em 1793, momento de consolidação dos ideais da Revolução Francesa, sob o Terror. A hipótese guia considera que as palavras não são as coisas, mas as representações “verdadeiras” das coisas e dos conceitos, nos atos de suas concepções primordiais. Se em princípio, as palavras podem ser consideradas “verdadeiras”, os atores políticos as desnaturam pela manipulação dos sentidos próprios e originais, findando por gerar ilusões para além de seus significados mais arraigados. Assim, o ensaio ao expor, transversal e criticamente, recortes de textos de Literatura e de Filosofia, conjuga citações e referências através de aforismos, dispostos em mosaico, cujo fundo dá a ver a possibilidade/impossibilidade de se confiar, de modo cabal, nas palavras circulantes, - ao menos naquelas utilizadas campo da ação política.
Change Detection of Vegetation Cover Using Remote Sensing and GIS – A Case Study of the West Coast Region of South Africa
Authors: Coetzee Clive 
Published: June 2022

This article investigates the possible permanent vegetation cover (VC) change over an extended time for five municipal regions in South Africa by applying satellite-acquired remote sensed normalized difference vegetation index (NDVI) values within a geographic information system (GIS), spatial (West Coast District) and time (1981 to 2019 and 2000 to 2020) context. The NDVI index measures surface reflectance and give a quantitative estimation of vegetation growth and biomass. The study found relevance in its application since VC change detection has taken prominence over the past number of years in terms of sustainable development. Methods of analysis include image mapping, temporal image differencing, Moran I statistic, and the Mann-Kendall trend test. In the main areas that recorded significant changes in their NDVI values (plus or minus 0.4 difference on their original NDVI value) over time, in general, have experienced substantial and permanent VC change. These areas are also spatially clustered and concentrated within specific areas within the wider district. However, these areas constitute only a minority of areas (less than 20%), whereas most of the areas within the district did not experience such significant and permanent change in VC. Instead, the changes that did occur in these majority of areas were related to seasonal variation, i.e., temporal changes.
Red tide monitoring method in coastal waters of Hebei Province based on decision tree classification
Authors: Yan Kang , Jinling Song , Mingming Bian , Haipeng Feng , Salama Mohamed 
Published: June 2022

Abstract
According to the water characteristics of the coastal waters of Hebei Province, this paper selects the data of the Marine Environmental Quality Bulletin of Hebei Province from 2009 to 2018 published on the website of the Department of Natural Resources of Hebei Province, and proposes a red tide monitoring method based on decision tree classification for the pre-processed MODIS 1B image data. The most important thing in the construction of decision tree is the determination of threshold, and this process is finally determined according to the value of Entropy. In this paper, the newly constructed red tide monitoring method is used to extract the occurrence area of red tide and count the red tide area. Finally, the decision tree classification method is compared with other typical red tide monitoring methods. The experimental results show that the red tide occurrence area and statistical area extracted by the red tide monitoring method based on decision tree classification are closer to the data displayed in the Ocean Bulletin, which demonstrates that this method is suitable for red tide monitoring in the coastal waters of Hebei Province.
Innovation in Quick Service Restaurants (QSRs): A Future Perspective
Authors: Singh Rajesh , Sarangal Rajani Kumari 
Published: June 2022

Abstract
The rationale of this study is to investigate the impact of innovative practices (product and service innovation) on customer satisfaction. Further study also tends to approach the impact of customer satisfaction on customer loyalty in quick service restaurants. The study has been conducted on potential customers of QSRs such as McDonald's, Dominos, Pizza Hut and KFC in Jammu city (J&K). A total of 256 samples were analyzed in the study. EFA and regression analysis have been used to identify the various factors and to test the relationship between the constructs, respectively. The study finds that innovative practices in QSRs positively influence customer satisfaction. Furthermore, the study also verified that customer satisfaction positively influences customer loyalty in selected QSRs.
Ethiopian Tourism, Legislation Gaps, and Implementation Challenges: A Study in Amhara Region
Authors: Weldesenbet Engdu Gebrewold , Meskeleb Ashenafi Tafesse 
Published: June 2022

Abstract
Tourism is a multispectrum and interagency puzzle, due to the impact many sectors have on this industry. As a result, laws are important to promote effective governance and policy approaches that help overcome sectorial gaps. But legislation might fail to meet its objectives and poor implementation can lead to long-term adverse consequences for the society and economy of the destination. This study analysed the major legislative gaps and implementation challenges. The study employed a descriptive study design with a cross-sectional research approach. Primary data was collected from 153 respondents through a questionnaire survey. The result from the study indicates that Ethiopian tourism legislation has acceptability, suitability and feasibility shortcomings. Concerning the challenges for effective implementation of tourism laws, the study found that there are stakeholder support–related challenges, economic challenges, coordination/bureaucracy–related challenges, and awareness-related challenges as well as ambiguity. The study also forwarded all the required recommendations for every stakeholder to ease legislative problems.
Les usages politiques de l’héritage antifasciste dans les relations franco-est-allemandes
Authors: Schmidt Franck 
Published: June 2022

Abstract
Im Frankreich der Nachkriegszeit löste die Rekonfiguration des politischen Feldes einen Wettstreit zwischen den politischen Akteuren um das Erbe der Résistance aus. Dieser Erbschaftstreit ist besonders deutlich zwischen der gaullistischen Bewegung und der kommunistischen Partei. In der sowjetischen Besatzungszone Deutschlands konstruierte die Deutsche Demokratische Republik (DDR) eine antifaschistische Liturgie, um sich besser von der nationalsozialistischen Vergangenheit distanzieren zu können. Auf diese Weise nahm die DDR das Erbe der deutschen Widerstandskämpfer für sich in Anspruch und baute einen Gründungsmythos für das neue Regime auf. Darüber hinaus nutzte die DDR diese „erfundene Tradition“ für ihre internationale Anerkennungskampagne. Die ostdeutsche Propaganda war in Frankreich besonders effizient, weil sie die dortigen politischen Verwendungen des Résistance-Erbes widerspiegelte.
Fisheries Processing Strategy In Jakarta In Improving Employee Performance
Authors: Ian Nurpatria Suryawan  
Published: June 2022

The owner of a fishery processing business in Jakarta seeks to improve employee performance by providing career development, good compensation, carrying out a recruitment strategy, and conducting a selection process. The population in this study was 6 (six) fishery processing businesses in Jakarta with a sample of 119 employees who were taken at random and only employees of the fishery processing department so that the sample taken did not include employees who had positions. Data collection was carried out in February 2022. The data processing used accidental sampling method. Results by research prove that career development can increase compensation and employee performance, recruitment strategy can increase compensation, selection can increase compensation, and employee performance and compensation can increase employee performance. Compensation does not significantly mediate career development, recruitment strategy, and selection of employee performance.
Antifungal Effects of Thymol-Loaded Chitosan Nanocomposite Alone and in Combined with Nystatin Against Candida Albicans, a Major Cause of Oral Candidiasis
Authors: Azadbakht Kamran , Hadipour Sara , Rashidipour Marzieh , Sepahvand Asghar 
Published: June 2022

Objectives:
Oral candidiasis is the most common oral infection that affects the oral mucosa. The most common oral thrush is caused by the fungus Candida albicans, but it can also be caused by Candida glabrata or Candida tropicalis. This study aimed to evaluate the antifungal effect of thymol-loaded chitosan nanocomposite in comparison with nystatin control drug on C. Albicans.

Material and Methods:
The obtained nanocomposite was characterized by scanning electron microscope (SEM), nanosizer-Zetasizer, and Fourier-transform infrared spectroscopy. Anti-Candida effects of thymol-loaded chitosan nanocomposite were assessed by evaluating the minimum inhibitory concentrations (MICs) and minimum fungicidal concentrations (MFCs) using broth microdilution method, according to the modified M60 protocol on yeasts, proposed by the Clinical and Laboratory Standards Institute.

Results:
Based on the results of SEM analysis, thymol-loaded chitosan nanocomposite with synthesized chitosan base shows a spherical shape. According to the size of the synthesized nanoparticles, the results showed that the size of nanoparticles varies from 100 to 600 nm, while most nanoparticles were between 200 and 300 nm with an average size of 295 nm. The lowest and the best MIC and MFC were related to the combination of nanoparticles + nystatin with 0.158 and 0.208 µg/ml, respectively. The results showed that the combination of nanoparticles + nystatin in comparison with nystatin group as a controlled drug showed a significant anti-Candida effect.

Conclusion:
The findings of the present in vitro study showed that thymol-loaded chitosan nanocomposite particularly along with nystatin showed promising antifungal effect against C. albicans as the main cause of oral candidiasis. Nevertheless, further investigations are required to elucidate the precise mechanism as well as systemic toxicity, especially in clinical settings.
NILAI MORAL DALAM NOVEL “RUMAH PUCAT” KARYA E. L. HADIANSYAH
Authors: Haga Kore Santri Patmiyani , Soleh Dwi Rohman , Winarsih Eni 
Published: June 2022

<p>Penelitian ini bertujuan untuk mendeskripsikan bentuk-bentuk nilai moral dalam novel <em>“Rumah Pucat”</em> karya E. L. Hadiansyah.Jenis penelitian ini adalah penelitian deskriptif kualitatif.Sumber data penelitian ini adalah novel <em>“Rumah Pucat”</em> karya E. L. Hadiansyah.Data penelitian ini berupa kutipan-kutipan novel “<em>Rumah Pucat”</em> karya E. L. Hadiansyah.Metode yang digunakan sebagai teknik pengumpulan data dalam penelitian ini adalah teknik observasi, teknik pustaka dan teknik catat.Instrumen dalam penelitian ini adalah peneliti sendiri, dengan mengumpulkan data.Teknik keabsahan data menggunakan teknik trianggulasi, Kemudian analisis data dilakukan peneliti untuk bersikap kritis, teliti, dalam membaca, mencatat, dan mengindentifikasi data tertulis. Analisis data denganmencaribukusumber, membaca novel danmencatatkutipan yang berkaitandengannilai moral.Hasil penelitian dalam novel tersebut menunjukkanbentuk-bentuk nilai moral dalam novel yaitu, nilai kebaikan dan nilai kerohanian.Nilaikerohaniansepertitekunberibadah, berdoabersamadannilaikebaikansepertisalingmembantu, peduli,ramah.</p><p> </p>
Computational Vibrational Spectroscopy
Authors: Meuwly Markus 
Published: June 2022

Vibrational spectroscopy is a powerful technique to characterize the near-equilibrium dynamics of molecules in the gas and the condensed phase. This contribution summarizes efforts from computer-based methods to gain insight into the relationship between structure and spectroscopic response. Methods for this purpose include physics-based and machine-learned energy functions, and methods that separate sampling conformational space and determining the data for spectral analysis such as map-based techniques.
Carga y rasgos de personalidad en cuidadores principales de personas mayores
Authors: Ramírez Zhindón Marina del Rocío , Arias Parra Johanna 
Published: June 2022

Teniendo en cuenta que el rol del cuidador informal en la vida del adulto mayor es primordial, se debe considerar también un posible incremento en la demanda del cuidado y probablemente ocasionarle una carga o sobrecarga, afectando diversas áreas de la persona a cargo. La carga en el cuidador puede definirse como “el nivel de tensión multifacética percibida por el cuidador informal hacia un familiar y/o ser querido por largo del tiempo” (Liu et al., 2020, p. 5). Ante la existencia de sobrecarga en el cuidador, los posibles efectos podrían presentarse como alteraciones y deterioro en la salud física y emocional, consecuencias negativas y disminución en la calidad de vida las cuales pueden ocurrir cuando el cuidado demanda más de los recursos disponibles. (Barreto-Osorio et al., 2015; Liu et al., 2020). El objetivo principal de esta investigación fue determinar la relación entre la sobrecarga y los rasgos de personalidad de 274 cuidadores informales de adultos mayores. En cuanto a los instrumentos utilizados fueron la entrevista de carga para cuidadores Zarit y el Cuestionario de Personalidad de Eysenck Revisado-Abreviado (Eysenck Personality Questionnaire Revised-Abbreviated [EPQR-A]). Entre los resultados más relevantes tenemos una correlación significativa de carga con los rasgos de personalidad neuroticismo y psicoticismo.