bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medically assisted reproduction and non-normative family forms:
legislation and public opinion in Europe
Authors: Compans Marie-Caroline , Zagel Hannah 
Published: January 2025

Abstract
This paper explores the relationship between access legislation of Medically Assisted Reproduction (MAR) and public attitudes towards family structures in Europe. It contributes to understanding the contextual frameworks that may facilitate the formation of a family outside the different-sex couple norm. The permissiveness of MAR policies has received political attention due to its potential to revolutionize family formation, with varying regulatory routes among states regarding access for single individuals and same-sex couples. We particularly examine regulatory trends in granting MAR access to single women and lesbian couples in Europe, and how legislation aligns with attitudes towards single motherhood and same-sex parenthood. Utilizing descriptive analysis and two-level models on original MAR legislation data across 36 European countries and the European Values Study (2008–10 and 2017–20) for attitudes, we show that MAR access is granted to lesbian couples in contexts where same-sex parenthood is accepted. By contrast, legalized MAR access for single women seems rather disconnected from public opinion towards single motherhood. As a whole, the paper delineates contexts in which the combination of social acceptance and legal permissibility of MAR use for non-normative prospective parents may favor the formation of ‘new’ family forms.
Rallying ‘round the Drag: Anti-gender Mobilization and the Mainstreaming of the Far Right
Authors: Volk Sabine 
Published: January 2025

Abstract
This article explores the link between anti-gender mobilization and the mainstreaming of the far right. It addresses the question of to what extent and how the far right allies with ‘mainstream’ actors in the context of anti-gender protest. Drawing from a social movement approach, the article contributes a novel operationalization of the mainstreaming of the far right in terms of discourse coalitions and protest alliances, with anti-gender frames working as a ‘symbolic glue’ between the far right and the mainstream, but also fringe actors on the extreme right. As a case study, the article focuses on anti-gender mobilization in Germany, fathoming the critical case of far-right Alternative for Germany (AfD). It adopts a localist perspective to analyze AfD's discourse coalitions and protest alliances in the context of a protest event against a ‘drag story hour’ in Munich in 2023. The qualitative protest event analysis demonstrates the only partial normalization of the far right in the context of anti-gender mobilization: While discourse coalitions between the far right and the mainstream have normalized, protest alliances remain a political taboo. Instead, at protest events the far right allies with fringe actors such as COVID-19 deniers, conspiracy activists, and right-wing extremists.
1.Truth and Reparations
Authors: Maya Llano Natalia , Domínguez Cardona Juan Camilo , Flórez Herrera Juan Sebastián , Puerta Henao Catalina , Rudling Adriana 
Published: January 2025

Colombia is the home of one of the most complex and ambitious transitional justice projects to date. This chapter traces the background and relationship of the Commission for the Clarification of Truth, Coexistence and Non-repetition to that project, and the participation of the higher education sector in that extra-judicial truth-seeking mechanism established in 2018. The main focal point of this chapter is a conversation with four researchers, practitioners and memory activists who participated in this work in different capacities. Since this conversation took place nearly six months following the release of the report of the Commission, the chapter concludes with a reflection on future directions for this type of work in Colombia.
Colombia alberga uno de los proyectos de justicia transicional más complejos y ambiciosos hasta la fecha. Este hace un recuento descriptivo de los antecedentes y la relación de la Comisión para el Esclarecimiento de la Verdad, la Convivencia y la No Repetición con ese proyecto y la participación del sector de la educación superior en ese mecanismo extrajudicial de búsqueda de la verdad establecido en 2018. El punto central de este capítulo es una conversación con cuatro investigadores, profesionales y activistas de la memoria que participaron en este trabajo de diferentes formas y partiendo de posiciones distintas. Dado que esta conversación tuvo lugar casi seis meses después de la publicación del informe de la Comisión, el capítulo concluye con una reflexión sobre las direcciones futuras para este tipo de trabajo en Colombia.
The Spanish language version of this chapter ("La verdad y las reparaciones: Una conversación sobre la participación del sector de la educación superior en la Comisión para el Esclarecimiento de la Verdad, la Convivencia y la No Repetición") is available at https://www.openbookpublishers.com/books/10.11647/obp.0427#resources and can also be downloaded as a DOCX file by clicking the 'Download' button above.
A Fast Nonparametric Sampling Method for Time to Event in Individual-Level Simulation Models
Authors: Garibay-Treviño David U. , Jalal Hawre , Alarid-Escudero Fernando 
Published: January 2025

Purpose. Individual-level simulation models often require sampling times to events; however, efficient parametric distributions for many processes may often not exist. For example, time to death from life tables cannot be accurately sampled from existing parametric distributions. We propose an efficient nonparametric method to sample times to events that does not require any parametric assumption on the hazards. Methods. We developed a nonparametric sampling (NPS) approach that simultaneously draws multiple time-to-event samples from a categorical distribution. This approach can be applied to univariate and multivariate processes. We discretize the entire period into equal-length time intervals and then derived the interval-specific probabilities. The times to events can then be used directly in individual-level simulation models. We compared the accuracy of our approach in sampling time-to-events from common parametric distributions, including exponential, gamma, and Gompertz. In addition, we evaluated the method’s performance in sampling age to death from US life tables and sampling times to events from parametric baseline hazards with time-dependent covariates. Results. The NPS method estimated similar expected times to events from 1 million draws for the 3 parametric distributions, 100,000 draws for the homogenous cohort, 200,000 draws from the heterogeneous cohort, and 1 million draws for the parametric distributions with time-varying covariates, all in less than 1 second. Conclusion. Our method produces accurate and computationally efficient samples for time to events from hazards without requiring parametric assumptions. Highlights The nonparametric sampling method is generic and can sample times to an event from any discrete (or discretizable) hazard without requiring any parametric assumption. The method is showcased with 5 commonly used distributions in discrete-event simulation models. The method produced very similar expected times to events, as well as their probability distribution, compared with analytical results. We provide a multivariate categorical sampling function for R and Python programming languages to sample times to events from processes with different hazards simultaneously.
Evaluation of a Depression Screening Program in Pediatric Orthopaedic Sports Clinics: Identifying At-Risk Adolescents
Authors: Colon-Morillo Reinaldo E. , Kartalias Katina , Bryan Tracey P. , Edmonds Eric W. 
Published: January 2025

Background: Mental health is a contributing factor to the overall well-being of patients, and the 2-question Patient Health Questionnaire (PHQ-2) and 9-question Patient Health Questionnaire (PHQ-9) are reliable in-clinic tools to assess depression and self-harm. The prevalence of adolescents with depression symptoms within a pediatric orthopaedic sports clinic has not been assessed. Hypothesis: That rates of depression and risk of self-harm would vary based on presenting pathology among adolescents sustaining a sports-related injury. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A query of the institutional electronic medical record was performed to identify all patients aged 12 to 21 years who were administered the PHQ-2 or PHQ-9 over a 2.3-year period within pediatric orthopaedic sports clinics. The rate of a positive screen prompting administration of PHQ-9 (PHQ-2 score ≥3), rate of depression risk (PHQ-9 score ≥10), and rate of patients indicating self-harm (affirmative score on question 9) were evaluated. Patients were placed into 4 broad diagnostic categories: knee instability, knee other, shoulder pathology, or other sports-related injuries. Multivariate binary logistic regression was performed to identify available patient and diagnosis predictors of self-harm risk. Results: A total of 3298 patients were screened in pediatric orthopaedic sports clinics from 2018 to 2021. The overall positive screen rate (PHQ-2) was 4.2% (n = 138), the depression risk rate (PHQ-9) was 1.9% (n = 63), and the self-harm rate was 0.9% (n = 29). Self-harm showed a significant difference, with shoulder and knee instability having the highest rate. Black/African American race (OR, 3.8; 95% CI, 1.3-11; P = .02), female sex (OR, 3.0; 95% CI, 1.3-6.9; P = .01), public/government insurance (OR, 2.2; 95% CI, 1.03-4.8; P = .041), shoulder pathology (OR, 3.4; 95% CI, 1.3-9.4; P = .016), and knee instability diagnosis (OR, 2.8; 95% CI, 1.2-6.5; P = .02) were associated with an increased risk of self-harm. Conclusion: This study demonstrated a 2% rate of depression risk and a 1% rate of self-harm risk in adolescents treated within pediatric orthopaedic sports clinics. Race, sex, and public/government insurance were found to be predictive factors. Knowledge of risk factors can help increase awareness and recognition of potential mental health conditions that may need to be addressed during treatment for adolescents with sports-related injuries. The authors recommend that adolescents >12 years of age complete this quick assessment at the start of their orthopaedic sports clinic encounter.
Tumor Mutation Signature Reveals the Risk Factors of Lung Adenocarcinoma with EGFR or KRAS Mutation
Authors: Wang Jialiang , Guo Chang , Wang Jiexiao , Zhang Xiaopeng , Qi Jian , Huang Xiang , Hu Zongtao , Wang Hongzhi , Hong Bo 
Published: January 2025

Introduction EGFR and KRAS mutations are frequently detected in lung adenocarcinoma (LUAD). Tumor mutational signature (TMS) determination is an approach to identify somatic mutational patterns associated with pathogenic factors. In this study, through the analysis of TMS, the underlying pathogenic factors of LUAD with EGFR and KRAS mutations were traced. Methods This was a retrospective study. TMS of LUAD with KRAS and EGFR mutations from the TCGA, OncoSG, and MSK datasets was determined by two bioinformatics tools, namely the “MutationalPatterns” and “FitMS” packages. Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) of LUAD clinical specimens was analyzed using capillary electrophoresis. Results In LUAD with KRAS mutations, TMS analysis indicated that the smoking-related SBS4 signature was enriched. For LUAD with EGFR L858R mutation, the smoking-related SBS4 signature was enriched in the Western population from the TCGA database; however, the smoking-related SBS4 signature was not obvious in Asian LUAD patients. LUAD with EGFR exon19 deletion (19Del) exhibited stronger SBS15 signature, which was related to defective DNA mismatch repair. Capillary electrophoresis analysis showed that an EMAST locus was frequently instable in LUAD with EGFR 19Del. Different from the Western population, Asian LUAD patients with EGFR mutations exhibited the enrichment of SBS1, SBS2, and SBS13 signatures, which were associated with the endogenous mutation process of cytidine deamination. Conclusions TMS analysis reveals that smoking is associated with LUAD with KRAS mutations. Defective DNA mismatch repair and endogenous cytidine deamination are associated with LUAD with EGFR mutations, especially for the EGFR 19Del. The endogenous mutational process is stronger in Asian LUAD patients than Western LUAD patients.
Operationalizing In-session Treatment Engagement Strategies and Behaviors for Adolescents With ADHD and Their Parents
Authors: Sibley Margaret H. , Rodriguez Lourdes M. , Lopez Melissa , Brochu Erika M. , Bracho Fabiana V. , Ortiz Mercedes , Hashimoto Jasmine 
Published: January 2025

Objective: Many treatment engagement challenges are documented for adolescents with ADHD. Across contexts, helping professionals (i.e., therapists, prescribers, educators, coaches) might benefit from an engagement strategy toolbox to facilitate work with adolescents with ADHD and their families. Method: The current study describes the development and psychometric testing of the ADHD Engagement Process Code (AEPC), a measure that operationalizes engagement strategies in the context of a blended behavioral/motivational interviewing treatment for adolescent ADHD (Supporting Teens’ Autonomy Daily; STAND). The AEPC also operationalizes in-session parent and adolescent engagement-related behaviors. Behavior counts and global codes were coded for 840 audio-recorded STAND sessions delivered by 21 therapists to 121 adolescents. Subsets of tapes were double coded using the AEPC’s parent, adolescent, and therapist coding systems to assess kappa for line-by-line verbalizations and intraclass correlations for session-level behavior counts and global scores. Construct validity was assessed. We explored low frequency and low variability codes and examined correlations between codes. Results: AEPC codes possessed good to excellent inter-rater reliability and strong discriminant validity. Three low frequency codes and one low variability global were identified indicating opportunities for AEPC refinement. Conclusions: The AEPC is publicly available ( https://osf.io/kshfy/ ) and offers a library of adolescent-specific codes for those interested in measuring provider, parent, or adolescent engagement behaviors in relevant populations or contexts.
Parents’ Experiences of Raising 7- to 11-Year-Old Children With ADHD and Perception of a Proposed Parenting Program: A Qualitative Study
Authors: Brown Louise E. , Tallon Mary , Kendall Garth , Boyes Mark , Myers Bronwyn 
Published: January 2025

Objective: To examine the experiences of Australian parents raising primary school-aged children with ADHD and gather feedback on a proposed ADHD parenting program. Methods: Reflexive thematic analysis of semi-structured interviews undertaken with 11 Australian parents of 7- to 11-year-old children with ADHD. Interviews were conducted over Webex, audio recorded, transcribed verbatim, and analyzed in NVivo Ltd. software. Results: We identified four themes: (1) “I love my child but their ADHD traits are challenging,” (2) “Compliance, control, and completion,” (3) “It’s hard, burdensome, and exhausting and I can feel like I’m alone,” and (4) “What a welcome relief.” Conclusion: Parents report that although raising neurotypical children is difficult, the presence of childhood ADHD increases the emotional and support burden placed on them. Parents were also very interested in and supportive of the proposed ADHD parenting program. The program aims to enhance parents’ understanding of the neurocognitive implications of ADHD and to foster secure parent-child attachment, attuned parental responsiveness, and age-appropriate development of traits that promote well-being, adaption and recovery in people with ADHD.)
Sine cosine optimization and balloon effect for adaptive load frequency control in microgrids with consirning of controlled loads
Authors: Hassan Ahmed Tawfik , Rashwan Asmaa Fawzy , Mosa Mohamed Roshdi , Mohamed Tarek Hassan , Mikhaylov Alexey , Hemeida Ashraf , Karpyn Zuleima 
Published: January 2025

It is important to put in place a reliable, effective, and flexible load frequency controller in order to guarantee stability in the microgrids (µGs). This paper presents an adaptive load frequency control (LFC) for an isolated µG with electric vehicles (EVs) and heat pump water heater (HPWH) systems. This adaptive control utilizes the balloon effect (BE) identification technique along with the sine cosine optimization (SCO) algorithm. The control system formulates the LFC process into an optimization problem that accommodates various random circumstances during control. With its unique use of the SCO + BE approach for adaptive LFC application, the recommended control technique produces a highly effective response. The efficacy of the suggested adaptive controller is evaluated *under conditions with a changing load of 17 MW and uncertainties in system parameters. A MATLAB Simulink-based digital testing environment is used to validate the results. According to the simulation results, the proposed adaptive controller effectively stabilizes the frequency and power in an islanded µG. A comparative study is conducted between the suggested control method and other strategies (e.g., Jaya-based adaptive controller and conventional integral controller) to gauge its effectiveness. Additionally, the positive impact of controlled loads, such as EVs and HPWHs, on system stability is demonstrated.
Cost Comparison of Intramedullary Screw Fixation Versus Open Reduction and Internal Fixation With Plate and Screw Technique for Metacarpal Fractures
Authors: Choo Stephanie , Faust Amanda , Troyer Luke , Philips Rachel , London Daniel A. , Nuelle Julia A. V. 
Published: January 2025

Background: Intramedullary screw (IMS) fixation for metacarpal fractures is a relatively new fixation technique in comparison to plate and screw constructs. Our hypothesis evaluated whether IMS fixation for metacarpal fractures results in lower overall health care–associated costs in comparison to open reduction and internal fixation (ORIF). Methods: A retrospective review of patients undergoing IMS fixation for metacarpal fractures at a single center during 2018 to 2022 was conducted. Health care–associated costs included primary operative costs (surgical time and implant(s)) and postoperative costs (therapy, splinting, and radiology). Costs were compared with age-matched and fracture pattern–matched controls who underwent ORIF with plate and screw construct. Subgroup analysis of cost outcomes excluding outliers was completed. Results: Eight subjects met the inclusion criteria and matched with an ORIF group. Primary operative costs were significantly higher in the ORIF group (mean difference of $1830, 95% CI: $1006 to $2653) The cost of an IMS at our institution was $584, whereas the average cost for plate and screw construct was $2538 (mean difference of $1953, 95% CI: $1665 to $2243). Total surgical costs were on average $3784 more for the ORIF group (95% CI: $2869 to $4700). There was no significant difference in outpatient follow-up costs (95% CI: −$441 to $3180). Total overall costs were significantly lower for the IMS group (95% CI: $2693 to $6513). Conclusions: Total primary operative costs and overall health care–associated costs for IMS fixation of metacarpal fractures is significantly lower than ORIF. There was no statistical difference in follow-up care costs. To better determine the indirect costs for patients, high-powered prospective studies will be required.
A Predictive Nomogram for Selective Screening of Chronic Kidney Disease: A Population-Based Study
Authors: Vo Nghia H. , Pham Bui V. , Nguyen Nghia N. , Nguyen Bao T. 
Published: January 2025

Objectives: Chronic kidney disease (CKD) is associated with disability, low quality of life, and mortality. However, most cases are asymptomatic, often detected incidentally, or only recognized when they have progressed to the later stages with complications. The present study aimed to determine the prevalence of CKD and develop a predictive nomogram for CKD in Vietnamese adults. Methods: This cross-sectional, population-based study involved 533 men and 957 women aged 18 years and older who were screened for CKD. The CKD was diagnosed using the albumin-to-creatinine ratio and/or estimated glomerular filtration rate by the CKD-EPI 2009 equation based on serum creatinine, age, gender, and race (these tests included a baseline measurement and a repeat measurement after 3 months) according to the KDIGO 2012 guideline. We used the Bayesian Model Averaging method to identify the optimal model for predicting CKD. A predictive nomogram was also developed to enable risk prediction. Results: The overall CKD prevalence was 13.1% (95% confidence interval [CI] = 11.6-14.6), with a prevalence of 11.8% (95% CI = 9.1-14.5) in men and 13.8% (95% CI = 11.6-16) in women. The optimal model for predicting CKD included age (odds ratio [OR] per 5-year increase = 1.19; 95% CI = 1.11-1.28), hypertension (OR = 2.08; 95% CI = 1.50-2.89), and diabetes (OR = 1.69; 95% CI = 1.18-2.43). The area under the receiver operating characteristic curve was 0.7, with a 95% CI ranging from 0.65 to 0.73. Conclusions: The CKD is relatively common among Vietnamese adults. A simple model—including age, hypertension, and diabetes—is helpful for the selective screening of CKD in Vietnamese individuals.
Narratives and Objects  of Worship in Early Medieval Bengal
Authors: Singh Vijaya Laxmi , Kumar Ranjan 
Published: January 2025

Abstract: The liturgical text Sūnya Puranā refers to the regional deity ‘Dharma Thakur’ as a ‘fertility deity’ associated with the agrarian class of society. The ploughman element of Bengali is ‘Shiva’, a revered peasant god who oversaw the seasonal cycle and ensured the fertility of the soil and the regeneration of the harvest. Around the time, the Dharma Thakur cult reflected the core necessities of Bengal’s rural agriculturalist society—good health, progeny and an abundance of food. Dharma Thakur implies all the movements and changes that the natural order is susceptible to. The immanent Dharma is contradictory in that he is a typical malignant-cum-protective village godhead: on the one hand, he looks out for the villagers, improving offspring and abundant crops, but on the other hand—failing to receive worship—he curses them with illnesses, barrenness and obstructions to plant regeneration. Bengali liturgical texts work as a base for didactic narration and religious performances in Bengal and Orissa. The religious performances of Gājan are based on religious narrations. Dharma worship is neither monotheist nor henotheist in nature. There is worship of symbols in the form of Kurma [tortoise]. Historians engage in debates about the religious significance of this worship. The stories mentioned in the liturgical texts show that the object of worship and its emergence are related to mythological stories where the chief deity was formless and had created many objects while creating the universe. Kurma was one of his creations. The emergence and popularity of an object of worship are always matters of sociopolitical change in a society. Bengal, during the phase of transition from Buddhist Pala rule to Brahmanic Sen rule, experienced a phase of political chaos. Buddhists had to migrate from Bengal, and due to this migration, a religious vacancy emerged in rural areas of Bengal. This situation benefited the local religious practitioners and helped in the emergence of the regional religious cult, Dharma Thakur. To look into the idea of such religious practices, it would be important to study it through contemporary religious writings. This article is an attempt at an honest reading of the tale of Dharma Thakur through the writings of Ramai Pandit.