bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance of Grade 8 Students in Mathematics Intervention Program
Authors: Francisco Jeanalyn G. , Alova Chard Aye R. , Alova Iana Menzi C. , Apohen Sharon L. 
Published: September 2022

Mathematics interventions are being provided for students nationwide who perform below basic on various assessments. The assessment of students’ performance in Mathematics gave rise to the conduct of this study. In this research, Grade 8 students who did not meet the expected competencies will have the opportunity to receive extra Mathematics assistance. Hence, this study is proposed so as to support the sustainability of Mathematics intervention program. This study is an action research utilizing survey questionnaire in order to determine the performance of the students in the pre- and post-tests of students under the Mathematics intervention program. The subject and the respondents of this study are the identified students in the Grade 8 who have not met the required competencies in Mathematics subject. Result showed that post-test result (Tutorial: 18.151±5.548; Remedial: 18.944±5.395) is higher than the pre-test result (Tutorial: 11.019±4.144; Remedial: 11.519±3.565) under tutorial program and remediation program. Result of the study also revealed that there is a significant difference between the performance of the students in the pre and post-test under tutorial program (t=-11.632, p=0.000) as well as in the performance of the students under remediation program tutorial program (W=0.000, p=0.000). Indeed, the aforementioned program is effective to improve the performance of students in Mathematics. Mathematics intervention program is effective to improve grades and performance of students, thus teachers should design a more improved techniques of this program.
Research Culture of Public Schools in Tagbilaran City, Bohol
Authors: Mangana Jhema Faith S. 
Published: September 2022

DepEd strives to promote and strengthen the culture of research in basic education. Along with this goal, this study aimed to determine the research culture and to recognize the extent of influence of the factors on research culture of public schools in Tagbilaran City, Bohol. It employed a quantitative descriptive research design with a survey questionnaire as the main instrument to gather the data needed in the study. Two instruments were utilized and modified in this study adapted from The Factors Influencing the Research Culture by Iqbal and colleagues and the Research Culture and Productivity of the Faculty of Accredited Private Higher Education Institutions by Tagaro. These were administered to 254 public school teachers as respondents from 25 public schools in DepEd Tagbilaran City Schools Division.
Findings revealed a moderate influence on the extent of influence of the factors on research culture of Tagbilaran City public schools. Among the factors, Environmental Factor had a greater influence whereas Personal Factor had a lesser influence on the research culture. There was no significant relationship between the teachers’ selected profile and the extent of influence on research culture however sex, designation, and highest educational attainment affect the research productivity level. Moreover, data showed that there was no correlation between the extent of influence of the factors on research culture and research productivity level of the teachers.
Direct, Indirect, and Combined Extracranial-to-Intracranial Bypass for Adult Moyamoya Disease: An Updated Systematic Review and Meta-Analysis
Authors: Nguyen Vincent N. , Motiwala Mustafa , Elarjani Turki , Moore Kenneth A. , Miller L. Erin , Barats Michael , Goyal Nitin , Elijovich Lucas , Klimo Paul , Hoit Daniel A. , Arthur Adam S. , Morcos Jacques J. , Khan Nickalus R. 
Published: September 2022

Background:
Moyamoya disease is a chronic, progressive cerebrovascular disease involving occlusion or stenosis of the terminal portion of the internal carotid artery. We conducted an updated systematic review and meta-analysis to investigate clinical and angiographic outcomes comparing direct, combined, and indirect bypass for the treatment of moyamoya disease in adults.

Methods:
Two independent authors performed Preferred Reporting Items for Systematic reviews and Meta-Analyses guided literature searches in December 2021 to identify articles reporting clinical/angiographic outcomes in adult moyamoya disease patients undergoing bypass. Primary end points used were ischemic and hemorrhagic strokes, clinical outcomes, and angiographic revascularization. Study quality was evaluated with Newcastle-Ottawa and the Oxford Center for Evidence-Based Medicine scales.

Results:

Four thousand four hundred fifty seven articles were identified in the initial search; 143 articles were analyzed. There were 3827 direct, 3826 indirect, and 3801 combined bypasses. Average length of follow-up was 3.59±2.93 years. Pooled analysis significantly favored direct (odds ratio [OR], 0.62 [0.48–0.79];
P
<0.0001; OR, 0.44 [0.32–0.59];
P
<0.0001; OR, 0.56 [0.42–0.74];
P
<0.0001; OR, 3.1 [2.5–3.8];
P
=0.0001) and combined (OR, 0.53 [0.41–0.69];
P
<0.0001; OR, 0.28 [0.2–0.41];
P
<0.0001; OR, 0.41 [0.3–0.56];
P
<0.0001; OR, 3.1 [2.8–4.3];
P
=0.0001) over indirect bypass for early stroke, late stroke, late intracerebral hemorrhage, and favorable outcomes, respectively. Indirect bypass was favored over combined (OR, 3.1 [1.7–5.6];
P
<0.0001) and direct (OR, 4.12 [2.34–7.25];
P
<0.0001) for early intracerebral hemorrhage. The meta-analysis significantly favored direct (OR, 0.37 [0.23–0.60];
P
<0.001; OR, 0.49 [0.31–0.77];
P
=0.002) and combined (OR, 0.23 [0.12–0.43];
P
<0.00001; OR, 0.30 [0.18–0.49];
P
<0.00001) bypass over indirect bypass for late stroke and late hemorrhage, respectively. Combined bypass was favored over indirect bypass for favorable outcomes (OR, 2.06 [1.18–3.58];
P
=0.01).

Conclusions:
Based on combined meta-analysis (43 articles) and pooled analysis (143 articles), the existing literature indicates that combined and direct bypasses have significant benefits for patients suffering from late stroke and hemorrhage versus indirect bypass. Combined bypass was favored over indirect bypass for favorable outcomes. This is a strong recommendation based on low-quality evidence when utilizing the Grades of Recommendation, Assessment, Development, and Evaluation system. These findings have important implications for bypass strategy selection.
When the Intellectuals of ‘Ḥarrān Contributed to Falsafa’
Authors: Awad Najib George 
Published: September 2022

Abstract
In this essay, I attend to an under-analyzed topic in the history of Kalām and Falsafa studies, the contribution of Theodore Abū Qurrah, a Melkite-Chalcedonian Arab-Speaking mutakallim of the early Abbasid era, to the Greek-Arabic translation movement and to Falsafa and Kalām, via the translations he made or through the philosophical ideas that underpin his own Kalām discourses. I will pay specific attention to a possible transmission of the Neoplatonic-Aristotelian heritage of Proclus through Abū Qurrah’s use of Proclean ideas in his own Christian Kalām. I will argue that some of Abū Qurrah’s literary output is expressive of his endeavor to develop an independent reading of Proclus and offer a fresh implementation of Proclean legacy in a Kalām-form that exceeds the boundaries of the traditional reading of Proclus. I will begin with insights on Kalām and the translation movement. I will move then to discuss the place of Ḥarrān (the city which Abū Qurrah belonged to and was the Melkite bishop in) on the map of the transmission of Greek sciences to Arabic, before paying attention to the role of the Bishop of Ḥarrān in this transmission activity. After setting the contextual framework, I will focus in the ensuing sections on some traces of Proclus’s legacy in Theodore Abū Qurrah’s extant texts.
الآثار النصّيّة: بين التناصّ والتوليد لخلق الوعي التاريخيّ
Authors: bin Tyeer (سارة بن طيير) Sarah R. 
Published: September 2022

المستخلص
إنّ لفظ/مفهوم التراث حديثٌ نسبيًّا، ويُطرح عادةً في النقاشات الأدبيّة عند الكلام عن الإطار النظريّ للتناصّ، وذلك لتنظير استعمال “التراث” أو الإحالة إليه. يحاجج هذا البحث، عن طريق رواية الزيني بركات لجمال الغيطانيّ نموذجًا، أنّ دراسة التناصّ في نصوصٍ تشتبك مع التراث تُغفل عادةً أهمّيّةَ النصّ القديم (المحال إليه) ووظيفتَه نتيجة الحدّ من دور المؤلّف. ولإيضاح هذه الفكرة أكثر، يستدعي البحث ما أسماه النقّاد القدامى “توليدًا،” وهو مصطلحٌ من بين مصطلحاتٍ كثيرة تشير إلى الإحالات الأدبيّة، وقد كان معتمدًا لدى بعضهم. ويرتبط التوليد عادةً باستخراج معنًى جديد من آخر قديم عن طريق استثماره أو الإضافة إليه. وبهذا، يحمل النصّ المولود رابطًا أسريًّا بالنصّ القديم؛ هو رابط البنوّة الأدبيّة بالمعنى المجازيّ. فالنصّ الجديد بمفهوم/معنى التراث هو الوريث الذي تُرك لاستثمارات مستقبليّة غرضُها النموّ والمنفعة‪.‬
La Niña Came to Eden
Authors: McPhaden Michael J. , Karamperidou Christina 
Published: September 2022

Abstract
In July 1929, Dr Friedrich Ritter and Dore Strauch left their spouses and the turmoil of post–World War I Germany for the remote, uninhabited, and rugged volcanic island of Floreana in the Galapagos archipelago. Their dream was to live self-sufficiently in an idyllic tropical setting unspoiled by civilization. Wealthy yachters stopping at Floreana in the early 1930s reported on the couple’s pioneering enterprise to the outside world. The news created a sensation that subsequently attracted other settlers, including a mysterious Viennese faux baroness who quickly sowed discord on the island. Not all the participants in this drama survived though. A prolonged drought gripped the island from 1933 to 1935 leading to food shortages that ultimately claimed the life of Dr. Ritter, a vegetarian who unwittingly ate tainted chicken out of desperation. The bizarre intrigues and struggles to endure on Floreana were chronicled in Dore Strauch’s 1936 memoir Satan Came to Eden and a 2013 Hollywood documentary based on it. A story that has not been told is how an extended period of cold La Niña conditions in 1933–35 led to the drought that caused the food shortages. We use an atmospheric reanalysis and other data sources to describe these cold conditions and how they affected the human drama that unfolded on Floreana Island. The protracted La Niña impacted other parts of the globe and in particular was a major influence on development of the 1930s Dust Bowl in the southern plains of the United States.
The Impact of COVID-19 on Mental Health in Medical Students: A Cross-Sectional Survey Study in Italy
Authors: Carletto Sara , Lo Moro Giuseppina , Zuccaroli Lavista Vittoria , Soro Giovanna , Siliquini Roberta , Bert Fabrizio , Leombruni Paolo 
Published: September 2022

Background: This study aimed to assess the impact of the COVID-19 pandemic in terms of the prevalence of anxiety, depression and stress symptoms in Italian medical students and to identify the associated factors. Design and Methods: A cross-sectional online survey was administered to second-sixth year medical students of the University of Torino, collecting data on the students’ sociodemographics, COVID-19 exposure, anxiety, depression and stress symptoms. Three hierarchical regressions adjusted for age, gender and year of study were executed. Results: The sample size was 1359. The prevalence of anxiety, depression symptoms, moderate perceived stress and severe perceived stress was 47.8%, 52.1%, 56.2% and 28.4%, respectively. The factors associated with mental health symptoms were: being a woman, a family history of psychiatric disorders, living off-site, competitive/hostile climates and unsatisfying friendships among classmates, poor relationships with cohabitants, negative judgment of medical school choice, fear of COVID-19 infection, feelings of loneliness, distressing existential reflections, and a worsening psychological condition related to the pandemic. Being in the fourth or sixth year constituted a protective factor for depression symptoms. Conclusions: Mental health in medical students was associated with both COVID-independent and COVID-related factors. Accessibility to effective interventions must be increased to counteract these changes.
Associations between adherence to the MIND diet and prevalence of psychological disorders, and sleep disorders severity among obese and overweight women: A cross-sectional study
Authors: Seifollahi Atefeh , Sardari Lilit , Yarizadeh Habib , Mirzababaei Atieh , Shiraseb Farideh , Clark Cain CT , Mirzaei Khadijeh 
Published: September 2022

Background The effect of dietary patterns on sleep disorders and mental illness has previously been investigated. However, these studies have reported contradictory findings, and thus, the present study aimed to assess the association of the MIND diet on the sleep pattern and mental health in obese women. Methods This is a cross-sectional study in which 282 women, aged 18–56 years with BMI ≥ 25 kg/m2.with no underlying diseases and malignancies, and participated. We used a semi-quantitative food frequency questionnaire (FFQ) to collect participant's dietary intake. The Pittsburgh Sleep Quality Index (PSQI) and Depression Anxiety Stress Scales (DASS) were used to measure the status of sleep disturbance and psychological disorders, including depression, anxiety, and stress respectively. Results A decreasing trend for psychological stress was observed in the highest quartiles of MIND diet score vs. the lowest quartiles (OR = 0.6 CI: 0.23–1.5 vs. 1.16 CI: 0.55–2.47). No significant difference was observed between severity of depression (OR = 0.87 95%, CI: 0.7–1.09, P = 0.23), anxiety (OR = 1.02, 95% CI: 0.81–1.27, P = 0.86), stress (OR = 0.99 95%, CI: 0.79–1.23, P = 0.92), and MIND diet adherence in the crude and adjusted models. Conclusion The main finding from this study was that there is no significant association between adherence to the MIND diet and studied psychological disorders.
Postoperative reproductive results of infertile patients with intrauterine adhesions: A retrospective analysis
Authors: Weng Xiu-Lan , Xie Xi , Liu Chao-Bin , Yi Jing-Song 
Published: September 2022

Objective To explore the reproductive outcomes after hysteroscopic separation of intrauterine adhesions (IUA) in infertile patients due to IUA. Methods This retrospective study enrolled patients with fertility requirements and infertility due to IUA. Data were collected from the hospital medical records and by follow-up by telephone. The impact on pregnancy and pregnancy outcome of preoperative adhesion, menstrual conditions before and after surgery and postoperative re-adhesion was analysed. Results A total of 106 patients (median age, 28 years) were enrolled in the study. There was a significant correlation between preoperative menstrual patterns and pregnancy rate. There were 56 pregnancies (pregnancy rate 52.83%) after the operation. Patients with improved menstruation after the operation had a significantly higher pregnancy rate (pregnancy rate 56.25%; 45 of 80 patients) compared with the patients that did not experience any improvement in their postoperative menstrual status (pregnancy rate 21.43%; three of 14 patients). Of the 56 pregnancies, 40 (71.43%) resulted in live births and six (10.71%) patients had miscarriages. A total of 54 of 56 patients (96.43%) became pregnant within 2 years. Conclusion Pregnancy after intrauterine adhesion separation has a high rate of miscarriage and obstetric complications, so close monitoring of the patient is required.
Flipped Classroom Models: A Rapid Review From Recent Literatures
Authors: Poudel Navin , Sharma Lekhnath 
Published: September 2022

Purpose This rapid review is based on 14 articles published in the year 2019 and 2020 that report on the flipped classroom. This review study aims to examine underpinning theories to design flipped classroom and the models of the flipped classroom utilized in the different disciplinary, curricular, and technological contexts. Design/Approach/Methods The ProQuest database was used to search the articles for the study with the keyword “flipped classroom” and “Flipped learning.” Cochrane rapid review method was used as a methodology to investigate theoretical underpinnings, models, and the disciplinary and technological context of the studies. Findings This study found that flipped classroom approach was practiced in various disciplinary contexts and was mostly based on the theory of constructivism. Technological use in the flipped classroom models ranges from just using videos to fully online using different applications and learning management systems. The findings of the studies showed that there is a positive impact of the flipped classroom on learning, motivation, and anxiety. Originality/Value This study utilized the Cochrane rapid review method in the educational setting.
Self-care practice, lived experience of type 1 diabetes mellitus patients at Kemisse General Hospital, North Eastern Ethiopia: Phenomenological study
Authors: Bogale Eyob Ketema , Wondiye Habtamu , Debela Yamrot , Fentabil Anagaw Tadele , Worku Lelisa , Kebede Natnael 
Published: September 2022

Objectives: To explore self-care experience of type 1 diabetes mellitus patients at Kemisse General Hospital, North east Ethiopia. Methods: A phenomenological study was conducted to explore self-care experience of type 1 diabetes mellitus patients at Kemisse General Hospital from 28 February 2020 to 15 March 2020. Participants were selected using a heterogeneous type of purposive sampling technique. Data were collected using in-depth interviews and observation with the aid of an audio recorder and interview guide by the principal investigator. The thematic analysis approach was used to analyze the data. To facilitate the data analysis process, Atlas. ti software version 7 was used. Results: The six interconnected themes that were emerged from the analysis are: (1) physical exercise, (2) dietary practice, (3) medication adherence, (4) self-monitoring of blood sugar, (5) problem-solving skill during hypoglycemia and hyperglycemia, and (6) diabetic foot care. Conclusion: The study described that type 1 diabetic patients at Kemisse general hospital faced difficulty in self-care practice, which were difficulty in medication adherence; foot care was neglected diabetes self-care, did not practice diabetes recommended dietary plan and lack of regular physical exercises. In addition to this, self-monitoring of blood sugar was not practiced regularly due to the absence of glucometer machine and financial constraints to buy test strips. In addition to diabetic patient’s role to manage hyperglycemia and hypoglycemic episode, family support was crucial to managing hypoglycemia because most of the respondent’s experience loss of consciousness during a hypoglycemic attack.
circ_0086296 induced atherosclerotic lesions via the IFIT1/STAT1 feedback loop by sponging miR-576-3p
Authors: Zhang Min , Zhu Yiqian , Zhu Jie , Xie Yi , Wu Ruihao , Zhong JiaYin , Qiu Zhaohui , Jiang Li 
Published: September 2022

AbstractExtensive inflammation of endothelial cells (ECs) facilitates atherosclerotic lesion formation. Circular RNA (circRNA) participates in atherosclerosis (AS)-related inflammation responses; however, whether and how circ_0086296 regulates atherosclerotic inflammation and lesions have not been investigated. Microarray analysis, quantitative real-time polymerase chain reaction, and fluorescence in situ hybridization assay were performed to detect the expression and location of hsa_circ_0086296 in human carotid artery plaques, aorta of atherosclerotic mice, and human umbilical vein endothelial cells (HUVECs). Sanger sequencing was used to verify the loop structure of circ_0086296. The relationship among circ_0086296, miR-576-3p, IFIT1, STAT1, and EIF4A3 was validated using bioinformatics, luciferase assay, RNA pull-down assay, and RNA immunoprecipitation. The atherosclerosis mouse model was used to evaluate the function of circ_0086296 in vivo. circ_0086296 expression was significantly upregulated in human carotid artery plaques, oxidized low-density lipoprotein (ox-LDL)-treated HUVECs, and the aorta of atherosclerotic mice. Functional analysis indicated that circ_0086296 promotes ECs injury in vitro and atherosclerosis progression in vivo. The mechanism analysis indicated that circ_0086296 sponged miR-576-3p to promote IFIT1–STAT1 expression. Moreover, STAT1 upregulated circ_0086296 expression, forming the circ_0086296/miR-576-3p/IFIT1/STAT1 feedback loop. Notably, inhibition of the circ_0086296/miR-576-3p/IFIT1 axis could block atherosclerotic lesion formation both in vivo and in vitro. Finally, circ_0086296 was overexpressed in exosomes of patients with atherosclerosis and exosomes of ox-LDL-treated ECs. Therefore, the circ_0086296/miR-576-3p/IFIT1/STAT1 feedback loop participates in atherosclerosis progression and contributes to the high circ_0086296 expression observed in the exosomes of serum of patients with atherosclerosis. This study sought to provide a deep understanding of the mechanisms underlying the aberrant EC phenotype in AS.
Genome-wide identification and expression analysis of the calmodulin-binding transcription activator (CAMTA) family genes in tea plant
Authors: Li Bo , He Shan , Zheng Yiqian , Wang Yu , Lang Xuxu , Wang Huan , Fan Kai , Hu Jianhui , Ding Zhaotang , Qian Wenjun 
Published: September 2022

Abstract
Background
As a type of calmodulin binding protein, CAMTAs are widely involved in vegetative and reproductive processes as well as various hormonal and stress responses in plants. To study the functions of CAMTA genes in tea plants, we investigated bioinformatics analysis and performed qRT-PCR analysis of the CAMTA gene family by using the genomes of ‘ShuChaZao’ tea plant cultivar.

Results
In this study, 6 CsCAMTAs were identified from tea plant genome. Bioinformatics analysis results showed that all CsCAMTAs contained six highly conserved functional domains. Tissue-specific analysis results found that CsCAMTAs played great roles in mediating tea plant aging and flowering periods. Under hormone and abiotic stress conditions, most CsCAMTAs were upregulated at different time points under different treatment conditions. In addition, the expression levels of CsCAMTA1/3/4/6 were higher in cold-resistant cultivar ‘LongJing43’ than in the cold-susceptible cultivar ‘DaMianBai’ at cold acclimation stage, while CsCAMTA2/5 showed higher expression levels in ‘DaMianBai’ than in ‘LongJing43’ during entire cold acclimation periods.

Conclusions
In brief, the present results revealed that CsCAMTAs played great roles in tea plant growth, development and stress responses, which laid the foundation for deeply exploring their molecular regulation mechanisms.
Response of soil microecology to different cropping practice under Bupleurum chinense cultivation
Authors: Liu Li , Cao Hailu , Geng Yannan , Zhang Quanfang , Bu Xun , Gao Demin 
Published: September 2022

AbstractThe effects of cropping practices on the rhizosphere soil physical properties and microbial communities of Bupleurum chinense have not been studied in detail. The chemical properties and the microbiome of rhizosphere soil of B. chinense were assessed in the field trial with three cropping practices (continuous monocropping, Bupleurum-corn intercropping and Bupleurum-corn rotation). The results showed cropping practices changed the chemical properties of the rhizosphere soil and composition, structure and diversity of the rhizosphere microbial communities. Continuous monocropping of B. chinense not only decreased soil pH and the contents of NO3−-N and available K, but also decreased the alpha diversity of bacteria and beneficial microorganisms. However, Bupleurum-corn rotation improved soil chemical properties and reduced the abundance of harmful microorganisms. Soil chemical properties, especially the contents of NH4+-N, soil organic matter (SOM) and available K, were the key factors affecting the structure and composition of microbial communities in the rhizosphere soil. These findings could provide a new basis for overcoming problems associated with continuous cropping and promote development of B. chinense planting industry by improving soil microbial communities.