bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the seismic performance of straight integral abutment bridges: From advanced numerical modelling to a practice‐oriented analysis method
Authors: Marchi Andrea , Gallese Domenico , Gorini Davide Noè , Franchin Paolo , Callisto Luigi 
Published: November 2022

AbstractThe seismic performance of integral abutment bridges (IABs) is affected by the interaction with the surrounding soil, and specifically by the development of interaction forces in the embankment‐abutment and soil‐piles systems. In principle, these effects could be evaluated by means of highly demanding numerical computations that, however, can be carried out only for detailed studies of specific cases. By contrast, a low‐demanding analysis method is needed for a design‐oriented assessment of the longitudinal seismic performance of IABs. To this purpose, the present paper describes a design technique in which the frequency‐ and amplitude‐dependency of the soil‐structure interaction is modelled in a simplified manner. Specifically, the method consists of a time‐domain analysis of a simplified soil‐bridge model, in which soil‐structure interaction is simulated by means of distributed nonlinear springs connecting a free‐field ground response analysis model to the structural system. The results of this simplified method are validated against the results of advanced numerical analyses, considering different seismic scenarios. In its present state of development, the proposed simplified nonlinear model can be used for an efficient evaluation of the longitudinal response of straight IABs and can constitute a starting point for a prospective generalisation to three‐dimensional response.
Integrated Assessment of Chemical and Biological Recovery After Diversion and Treatment of Acid Mine Drainage in a Rocky Mountain Stream
Authors: Kotalik Christopher J. , Meyer Joseph S. , Cadmus Pete , Ranville James F. , Clements William H. 
Published: November 2022

Abstract
Responses of stream ecosystems to gradual reductions in metal loading following remediation or restoration activities have been well documented in the literature. However, much less is known about how these systems respond to the immediate or more rapid elimination of metal inputs. Construction of a water treatment plant on the North Fork of Clear Creek (NFCC; CO, USA), a US Environmental Protection Agency Superfund site, captured, diverted, and treated the two major point-source inputs of acid mine drainage (AMD) and provided an opportunity to investigate immediate improvements in water quality. We conducted a 9-year study that included intensive within- and among-year monitoring of receiving-stream chemistry and benthic communities before and after construction of the treatment plant. Results showed a 64%–86% decrease in metal concentrations within months at the most contaminated sites. Benthic communities responded with increased abundance and diversity, but downstream stations remained impaired relative to reference conditions, with significantly lower taxonomic richness represented by a few dominant taxa (i.e., Baetis sp., Hydropsyche sp., Simulium sp., Orthocladiinae). Elevated metal concentrations from apparent residual sources, and relatively high conductivity from contributing major ions not removed during the treatment process, are likely limiting downstream recovery. Our study demonstrates that direct AMD treatment can rapidly improve water quality and benefit aquatic life, but effectiveness is limited, in part, to the extent that inputs of metals are captured and treated. Consideration should also be given to the effects of elevated major ion concentrations from the treated effluent not removed during the lime treatment process. Continued chemical and biological monitoring will be needed to quantify the NFCC recovery trajectory and to inform future remediation strategies. Environ Toxicol Chem 2023;42:512–524. © 2022 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.
The microbial‐killing Ag nanoparticles in food supply chain: How it was applied and what a consumer should know?
Authors: Yeap Swee Pin , Rajendran Salini Devi , Wahab Siti Norida 
Published: November 2022

AbstractMoving to 133 years of the synthesis of citrate‐stabilized silver nanoparticles (AgNPs) by M. C. Lea (published in Am. J. Sci, 1889), a myriad of scholarly works and patents were published globally demonstrating the applicability of this microbial‐killing nanoparticles in various industries. One of the favorite applications is on the food supply chain whereby AgNPs serve to improve food safety and quality. In this paper, the adaptation of AgNPs in each phase of a typical food supply chain is disclosed, doubts associated with the potential risks brought by this technology, and what a consumer shall be aware of are highlighted.
Comparison of chemical compositions, antioxidant activities, and acetylcholinesterase inhibitory activities between coffee flowers and leaves as potential novel foods
Authors: Shen Xiaojing , Nie Fanqiu , Fang Haixian , Liu Kunyi , Li Zelin , Li Xingyu , Chen Yumeng , Chen Rui , Zheng Tingting , Fan Jiangping 
Published: November 2022

AbstractThis study aimed to compare chemical compositions, antioxidant activities, and acetylcholinesterase inhibitory activities of coffee flowers (ACF) and coffee leaves (ACL) with green coffee beans (ACGB) of Coffea Arabica L. The chemical compositions were determined by employing high‐performance liquid chromatography–mass spectroscopy (HPLC–MS) and gas chromatography–mass spectroscopy (GC–MS) techniques. Antioxidant effects of the components were evaluated using DPPH and ABTS radical scavenging assays, and the ferric reducing antioxidant power (FRAP) assay. Their acetylcholinesterase inhibitory activities were also evaluated. The coffee sample extracts contained a total of 214 components identified by HPLC‐MS and belonged to 12 classes (such as nucleotides and amino acids and their derivatives, tannins, flavonoids, alkaloids, benzene, phenylpropanoids, and lipids.), where phenylpropanoids were the dominant component (>30%). The contents of flavonoids, alkaloids, saccharides, and carboxylic acid and its derivatives in ACF and ACL varied significantly (p < .05) compared to similar components in ACGB. Meanwhile, 30 differentially changed chemical compositions (variable importance in projection [VIP] > 1, p < .01 and fold change [FC] > 4, or <0.25), that determine the difference in characteristics, were confirmed in the three coffee samples. Furthermore, among 25 volatile chemical components identified by GC–MS, caffeine, n‐hexadecanoic acid, 2,2′‐methylenebis[6‐(1,1‐dimethylethyl)‐4‐methyl‐phenol], and quinic acid were common in these samples with caffeine being the highest in percentage. In addition, ACL showed the significantly highest (p < .05) DPPH radical scavenging capacity with IC50 value of 0.491 ± 0.148 mg/ml, and acetylcholinesterase inhibitory activity with inhibition ratio 25.18 ± 2.96%, whereas ACF showed the significantly highest (p < .05) ABTS radical scavenging activity with 36.413 ± 1.523 mmol trolox/g Ex. The results suggested that ACL and ACF had potential values as novel foods in the future.
Retinal regions shape human and murine Müller cell proteome profile and functionality
Authors: Kaplan Lew , Drexler Corinne , Pfaller Anna M. , Brenna Santra , Wunderlich Kirsten A. , Dimitracopoulos Andrea , Merl‐Pham Juliane , Perez Maria‐Theresa , Schlötzer‐Schrehardt Ursula , Enzmann Volker , Samardzija Marijana , Puig Berta , Fuchs Peter , Franze Kristian , Hauck Stefanie M. , Grosche Antje 
Published: November 2022

AbstractThe human macula is a highly specialized retinal region with pit‐like morphology and rich in cones. How Müller cells, the principal glial cell type in the retina, are adapted to this environment is still poorly understood. We compared proteomic data from cone‐ and rod‐rich retinae from human and mice and identified different expression profiles of cone‐ and rod‐associated Müller cells that converged on pathways representing extracellular matrix and cell adhesion. In particular, epiplakin (EPPK1), which is thought to play a role in intermediate filament organization, was highly expressed in macular Müller cells. Furthermore, EPPK1 knockout in a human Müller cell‐derived cell line led to a decrease in traction forces as well as to changes in cell size, shape, and filopodia characteristics. We here identified EPPK1 as a central molecular player in the region‐specific architecture of the human retina, which likely enables specific functions under the immense mechanical loads in vivo.
Endoscopic transoral approach to the lateral poststyloid space
Authors: Li Lifeng , Xu Hongbo , London Nyall R. , Carrau Ricardo L. , Jin Yonggang , Chen Xiaohong 
Published: November 2022

AbstractThe lateral poststyloid space (LPSS) located at the posterolateral aspect of the styloid process. This study aims to explore the anatomical relationships in LPSS via a transoral corridor, providing reference for addressing lesions extending to this region. An endoscopic transoral approach for exposure of the LPSS was performed on 6 cadaveric specimens (12 sides). Related landmarks were explored, and transoral extirpation of tumors extended into LPSS was employed in 12 patients. The deep lobe of the parotid gland, extratemporal facial nerve, and the accompanying artery in the LPSS were sufficiently exposed via the transoral corridor in all 12 cadaveric sides. The transoral corridor provided adequate exposure for tumors extending to the LPSS, and en bloc resection was achieved in these 12 patients. No facial nerve or vascular injury occurred, and no recurrence observed in this cohort with an average follow‐up of 26 months. An endoscopic transoral approach provides a direct access to the LPSS. Appreciation of the anatomical relationships within the LPSS is valuable for employing a transoral extirpation of tumors extending to this specific region.
Time‐varying prognostic value of primary tumor sidedness in metastatic colorectal cancer: A population‐based study and meta‐analysis
Authors: van der Kruijssen Dave E. W. , van der Kuil Auke J. S. , Vink Geraldine R. , Punt Cornelis J. A. , de Wilt Johannes H. W. , Elias Sjoerd G. , Koopman Miriam 
Published: November 2022

AbstractWe studied the prognostic value of primary tumor sidedness in metastatic colorectal cancer over time and across treatment lines. Population data on synchronous metastatic colorectal cancer patients were extracted from the Netherlands Cancer Registry and SEER database. Pubmed, EMBASE and Cochrane library were searched for prospective studies on metastatic colorectal cancer to conduct a meta‐analysis. Inclusion criteria consisted of metastatic disease, systemic treatment with palliative intent and specification of primary tumor location. Data were pooled using a random‐effects model. For the population‐based data, multivariable Cox models were constructed. The Grambsch‐Therneau test was conducted to evaluate the potential time‐varying nature of sidedness. Meta‐regression incorporating treatment‐line as variable was conducted to test the pre‐specified hypothesis that the prognostic value of sidedness varies over time. Analysis of 12 885 and 16 160 synchronous metastatic colorectal cancer patients registered in the Netherlands Cancer Registry and SEER database, respectively, indicated a time‐varying prognostic value of sidedness (P < .01). Thirty‐one studies were selected for the meta‐analysis (9558 patients for overall survival analysis). Pooled univariable hazard ratioleft‐sided/right‐sided for overall survival was 0.71 (95% CI: 0.65‐0.76) in 1st‐line, 0.76 (0.54‐1.06) in 2nd‐line and 1.01 (0.86‐1.19) in 3rd‐line studies. Hazard ratios were significantly influenced by treatment line (P = .035). The prognostic value of sidedness of the primary tumor in metastatic colorectal cancer patients treated with palliative systemic therapy decreases over time since diagnosis, suggesting that sidedness may not be a useful stratification factor in late‐line trials. This decrease in prognostic value should be taken into account when providing prognostic information to patients.
Bank market power and performance of financial technology firms
Authors: Andrikopoulos Athanasios , Dassiou Xeni 
Published: November 2022

AbstractWe adopt a novel variation of the traditional structure‐conduct‐performance modelling approach, looking atbetween, rather thanwithin, industries to study the impact of changes in the bank market structure on the corporate performance of financial technology (fintech) firms using firm‐level data. We use two samples, one with 231 fintech firms and one with 231 non‐fintech firms across 24 industrialized countries over the 10‐year period from 2008 to 2017. We find that changes in bank market power have a positive impact on the performance of fintech companies suggesting that such firms complement rather than compete with banks. On the other hand,withinthe non‐fintech sector, we find that changes in bank market power have no impact on non‐fintech firms. Our results are robust to several tests.
Political risk and environmental quality in Brazil: Role of green finance and green innovation
Authors: Kirikkaleli Dervis , Adebayo Tomiwa Sunday 
Published: November 2022

AbstractThe quest for ecological sustainability while reducing the impacts of environmental deterioration has become a worldwide endeavour. Furthermore, it is unclear how developing economies such as Brazil can considerably improve environmental quality (EQ). This paper contributes to the ongoing literature by evaluating the effect of green finance, economic growth, political risk, social globalization and green innovation on environmental quality in Brazil. The study used data spanning between 2000Q1 and 2018Q4. Unlike other investigations, the current study used load capacity factor as a proxy for environmental quality, which considers both demand and supply sides of environmental issues. The current study applied the novel dynamic ARDL to capture the short and long‐run nexus. The bootstrap causality test was also applied to capture causal connection instabilities over time. The results of this study are as follows: (1) a significant and positive association was found between political risk, green finance, green innovation and social globalization environmental quality; (2) a significant and negative interplay was detected between economic growth and environmental quality; (3) The time‐varying causality shows a feedback causality at various periods between political risk, green finance, green innovation, economic growth, social globalization and environmental quality. This study also serves as a reference point for governments and policymakers in terms of investing in eco‐friendly technologies in order to improve environmental quality.
Evaluation and comparison of the accuracy of transvaginal ultrasound and MRI for the diagnosis of deep rectal endometriosis: A cross‐sectional study
Authors: Alborzi Saeed , Poordast Tahereh , Askary Elham , Javedanmehr Masoomeh , Shahraki Mahboobeh Hamedi , Alborzi Soroosh , Abadi Alimohammad Keshtvarz Hesam 
Published: November 2022

AbstractObjectiveTo determine and compare the value of magnetic resonance imaging (MRI) and transvaginal sonography (TVS) in the diagnosis of rectal endometriosis.MethodsIn this cross‐sectional study, 555 patients with rectal endometriosis, who had undergone MRI and TVS before laparoscopic operation, were included. The sensitivity, specificity, and accuracy of these two imaging modalities were evaluated and compared based on histopathologic reports and three different kinds of rectal endometriosis surgeries (shaving as a first group and disk and segmental resection methods combined as a second group).ResultsSensitivity, specificity, accuracy, positive predictive value, negative predictive value, positive likelihood ratio, and negative likelihood ratio of ultrasound in the diagnosis of rectal endometriosis were, respectively, 69.55% (65.4%–73.4%), 91.30% (72%–98.9%), 70.4% (66.4%–74.17%), 11.48% (9.77%–13.43%), 99.46% (98%–99.86%), 8.0 (2.12–30.1), and 0.3 (0.28–0.4). These values were 51.37% (47.1%–55.6%), 79.17% (57.8%–92.9%), 52.53% (48.3%–56.6%), 6.64% (5.39%–8.16%), 98.26% (96.26%–99.2%), 2.47 (1.13–5.4), and 0.6 (0.49–077) for MRI. Even though ultrasound had better accuracy for detection of superficial rectal endometriosis (Group 1) (P < 0.001), the sensitivity, specificity, and accuracy of both imaging modalities in diagnosis of deep rectal lesions (Group 2) were almost identical.ConclusionTVS should be considered as a first‐line modality for diagnosis of rectal endometriosis, mainly because of its greater availability, lower cost, and higher accuracy.
Comparison of recurrence rate and risk factors in patients with focal adenomyosis with and without medical treatment after conservative surgery
Authors: Wang Wenwen , Ma Xiangyi , Zhang Minli , Wu Zhangying , Xiang Tao , Wang Shixuan 
Published: November 2022

AbstractObjectiveTo compare the recurrence rate and risk factors between conservative surgery followed by medical treatments and conservative surgery‐only in patients with focal adenomyosis.MethodsThis retrospective study was conducted in a single teaching hospital from May 2011 to October 2016. All eligible patients were identified into three groups: surgery‐only group, surgery combined with gonadotropin‐releasing hormone agonist (GnRHa), and a levonorgestrel‐releasing intrauterine system (LNG‐IUS) group. The recurrence rate and risk factors were compared among groups using Kaplan–Meier and Cox proportional hazards analyses. Receiver operating characteristic (ROC) curve analysis was applied to determine a cut‐off value for identifying recurrence‐related risk factors.ResultsA total of 249 postoperative patients with adenomyosis were included in the final analysis with a mean of 41 months of follow up. The recurrence rate at the long‐term follow up was significantly lower in intervention groups than in the surgery‐only group (P = 0.011). The Cox proportional hazards and ROC analyses showed that a menstrual cycle longer than 26 days (P = 0.026), diameter of lesions <6 cm (P = 0.030), and combination treatment using GnRHa (P = 0.039) or LNG‐IUS (P = 0.007) were protective against relapse. The risk of recurrence was lower in patients with anterior (P = 0.034) or fundus (P = 0.038) adenomyosis.ConclusionPostoperative therapy using GnRHa or LNG‐IUS decreases the long‐term relapse rate in women undergoing conservative surgery.
Group lying with negative externality
Authors: Yao Lan , Zhou Chong 
Published: November 2022

AbstractWe use a modified die‐rolling experiment to study whether negative externality affects a group's decisions about whether to cheat. Our results show that group members are less likely to lie when faced with a passive out‐group player only if two members of the group share an unequal payment for lying. The less‐paid party in the group plays a dominant role in the honest decision by proposing the true number more frequently in arguments for group coordination.
Teaching about climate change: Possibilities and challenges in Australian adult literacy programs
Authors: Yasukawa Keiko 
Published: November 2022

AbstractAustralia's natural environment poses challenges for human inhabitants and will continue to pose novel challenges in an era of climate change. However, the resources that people can access to respond to climate change are diverse and unequally distributed. While this suggests a role for education, especially for those who are most socially and economically vulnerable, integrating climate change literacy into educational programs is not straightforward in all sectors. Studies have shown that increased standardization of curricula constrain teacher autonomy and pose dilemmas for teachers faced with tensions between curricular requirements and their professional judgment about appropriate pedagogy and curricula. This article considers the possibility of educational intervention for socially and economically disadvantaged adults with limited English language and literacy skills by investigating how a group of teachers in accredited literacy courses viewed their role in addressing climate change and environmental literacy in their literacy classes.
Qualitative analysis of a community pharmacy practice transformation initiative
Authors: Bacci Jennifer L. , Ferreri Stefanie P. , Coley Kim C. , Daly Christopher J. , Hake Kelsey L. , Herbert Sophia M. C. , Hughes Tamera D. , McDonough Randal P. , Roller Jessica S. , McGivney Melissa Somma , Smith Megan , Doucette William R. 
Published: November 2022

AbstractObjectiveTo evaluate practice transformation team (PTT) members' perceptions of the Flip the Pharmacy (FtP) initiative as a strategy for implementing and improving community pharmacy‐based patient care.MethodsFtP is a national 2‐year practice transformation initiative for implementing enhanced patient care and medication optimization services at community pharmacies, launched in 2019 with 28 PTTs including over 500 pharmacy locations. Key informant interviews were conducted with team leads, coaches, and pharmacy champions from four PTTs that participated in the first FtP cohort. The interviews were conducted using semistructured interview guides based on the RE‐AIM framework and focused on participants' experiences in the first year of FtP. Interviews were audio‐recorded, transcribed, and analyzed using a rapid content analysis approach.ResultsFour leads, 8 coaches, and 8 pharmacy champions were interviewed from 4 PTTs from May to October 2021 and resulted in 10 themes: (1) community pharmacy practice experience is important when selecting coaches; (2) team readiness supports successful pharmacy practice transformation; (3) measures of patient care quality are needed; (4) payment and practice transformation opportunities happen in parallel; (5) successful practice transformation requires strategic involvement of the entire pharmacy team; (6) FtP practice transformation domains are synergistic; (7) change packages, coaching, and performance monitoring are core practice transformation supports; (8) pharmacy teams value opportunities to share and learn from each other; (9) sustaining patient care services is continuous; and (10) COVID‐19 accelerated practice transformation while creating new stress points.ConclusionParticipants in this study perceived the FtP initiative as a helpful strategy implementing and improving community pharmacy‐based patient care. Future research should explore the sustainability of the FtP initiative and similar community pharmacy practice transformation efforts.