bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efektifitas Rom Pasif terhadap Tonus Otot Pasien Post-Operasi Fraktur Ekstremitas di Kecamatan Bekri Lampung Tengah
Authors: Jamaludin Djunizar Jamaludin , Kusumaningsih Dewi Kusumaningsih , Prasetyo Heru Prasetyo 
Published: October 2022

ABSTRAK Kasus fraktur didunia sebanyak 12 juta orang ditahun 2008 dengan angka kejadian sebanyak 2,6%. Terdapat kasus 17 juta orang di tahun 2009 dengan angka kejadian sebanyak 3,2% (Murtanto, 2021). Penggunaan uji tonus otot serta sendi secra mandiri dengan nama MMT (Manual Muscle Testing). Teknik uji ini memakai skala 0-5. Tujuan: guna pertahankan dan maksimalkan tonus otot dan sendi menggunakan latihan Range of Motion (ROM). Metode: fisioterapi latihan range of motion (ROM) pasif dilakukan selama 1x selama 3 hari. Hasil: tonus otot pada hari pertama dari ketiga pasien dengan nilai rata-rata 2 lebih rendah dibanding dengan hari ketiga dengan hasil tonus otot 4. Hal ini menunjukkan bahwa pasien mengalami perbaikan dituangkankan hasil dalam tabel tonus otot. Kesimpulan: latihan range of motion pasif pada tonus otot terbukti efektif dilakukan untuk pasien dengan gangguan mobilitas post op fraktur esktermitas. Kata Kunci: ROM (Range Of Motion), Post-Operasi, Tonus Otot. ABSTRACT The trend of the prevalence of injuries showed an increase from 7.5% in 2017 to 8.2% in 2018 (Kemenkes RI, 2018). Surgery aims to save lives, prevent disability and complications (Safitri, 2015). Using manual muscle and joint testing is called MMT (Manual Muscle Testing). This examination aims to determine the ability of muscles and joints to voluntarily contract joint muscle groups. The MMT method uses a scale of 0-5. Goal: maintain or increase muscle and joint strength by using Range of Motion (ROM). Methods: passive range of motion (ROM) exercise physiotherapy was performed once for 3 days. Results: muscle tone on the first day of the three patients with an average value of 2 was lower than on the third day with a muscle tone result of 4. This indicates that the patient has improved, the results are stated in the muscle tone table. Conclusion: Passive range of motion exercises on muscle tone strength have been proven to be effective for patients with post-op mobility disorders of extremity fractures. Keywords: ROM (Range Of Motion), Post-Operation, Muscle Tone.
Efek Antiaterogenik Ekstrak Pakis Sayur (Diplazium esculentum) melalui Penghambatan Vascular Cell Adhesion Molecule-1 pada Tikus Model Aterogenik
Authors: Urvina Tristira , Sulistyaningsih Erma , Sutejo Ika Rahmawati 
Published: October 2022

ABSTRACT Atherosclerosis is one cause of death. The thickening of the arterial walls which form atherosclerotic plaque can cause a blockage of the artery lumen and lead to thrombosis and blood flow. VCAM-1 activation causes increased adhesion of monocytes to endothelial walls and foam cell formation which is the key to the occurrence of atherosclerosis. Diplazium esculentum contains antioxidants and is able to inhibit the activation of VCAM-1. This study aimed to determine the effect of vegetable fern extract on the expression of VCAM-1 as an anti-atherogenic effect and the effective dose required. Experimental studies using randomized post test only control group design. Samples were grouped into 7 groups, namely K, KN, P1, P2, P3, P4, and P5. All group except K induced by atherogenic diet ang followed by the granting of vegetable fern extracts of 300 mg/kgBW in P1 groups, 600 mg/kgBW in P2 groups, 900 mg/kgBW in P3 groups, 1200 mg/kgBW in P4 groups, and 1500 mg/kgBW in P5 groups. The results showed a correlation between the dose of the extract given by the expression of VCAM-1, the greater the dose given VCAM-1 will be further hampered. The effective dose in rats was 2707, 19 mg/kg, this dose is equivalent to 4 kg of fresh vegetables fern in humans. Keywords: Atherosclerosis, Vegetable Fern Extract, VCAM-1 ABSTRAK Aterosklerosis merupakan salah satu penyebab kematian. Penebalan dinding arteri yang membentuk plak aterosklerosis dapat menyebabkan penyumbatan lumen arteri dan mengakibatkan trombosis dan gangguan aliran darah. Aktivasi VCAM-1 menyebabkan peningkatan perlekatan monosit pada dinding endotel dan pembentukan foam cell yang merupakan kunci terjadinya aterogenesis. Diplazium esculentum mengandung senyawa aktif yang bersifat antioksidan dan mampu menghambat aktivasi VCAM-1. Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak pakis sayur terhadap ekspresi VCAM-1 sebagai efek antiaterogenik dan dosis efektif yang diperlukan. Studi eksperimental menggunakan randomized post test only control group design. Sampel dikelompokkan menjadi 7 kelompok, yaitu K, KN, P1, P2, P3,P4, dan P5. Tiap kelompok diinduksi diet aterogenik dilanjutkan dengan pemberian ekstrak pakis sayur sebesar 300 mg/kgBB, 600 mg/kgBB, 900 mg/kgBB, 1200 mg/kgBB, dan 1500 mg/kgBB. Hasil penelitian menunjukkan terdapat hubungan antara dosis ekstrak yang diberikan dengan ekspresi VCAM-1, semakin besar dosis yang diberikan ekspresi VCAM-1 akan semakin terhambat. Dosis efektif pada tikus adalah 2707, 19 mg/kgBB, dosis ini setara dengan 4 kg pakis sayur segar pada manusia. Kata Kunci: Aterosklerosis, Ekstrak Pakis Sayur, VCAM-1
sistema EMA-EMAI: una forma heurística de apoyar la formación músico-interpretativa
Authors: Rodrigues Da Silva Anderson 
Published: October 2022

Resumen
El presente escrito plantea una posible vía para el trabajo y el aprendizaje del acto interpretativo-musical direccionado hacia un público, también conocido como performance musical: se trata del sistema Expresividad Musical Activa (EMA) y Expresividad Musical Activa con el Instrumento (EMAI). Dicho sistema consiste en la participación activa del educando en su proceso de construcción del discurso musical de una manera ecológica y heurística, conectando cíclicamente sus conocimientos previos con los nuevos hallazgos identificados por sí mismo. Por ello, el autor fundamenta esa forma inventiva de erigir el aprendizaje de una obra musical en los parámetros de la expresividad musical, la Atención Plena y en la relación músico-emocional, con la mira en proporcionar, así, una atmósfera propicia para un aprendizaje significativo de una manera inherentemente musical.
importancia del trabajo con el álbum familiar desde una perspectiva feminista
Authors: Barragán Campos Gabriela 
Published: October 2022

El propósito del texto es presentar, a grandes rasgos, la propuesta que se propone en el libro What can a woman do with a camera? (libro póstumo, editado por la artista británica Jo Spence) respecto al trabajo con el álbum familiar y las autobiografías visuales. La propuesta que se presenta ahí, tiene que ver con un trabajo que integra las fotografías “domésticas” o privadas y que tiene como propósito revelar las luchas de poder más naturalizadas al interior de la familia, algo que no suele ser visible en los archivos fotográficos familiares, siendo así una manera de trabajar con el llamado “inconsciente óptico familiar” (Hirsch 2012). Y es que, si bien para muchas personas la familia representa un espacio de seguridad, cercanía o aceptación, para muchas otras no lo es. Esta propuesta de Jo Spence si bien inspiraría a muchas otras artistas a trabajar con su propio álbum, se presentó, antes que nada, para que se la apropiase cualquier mujer o grupo, colectivo o comunidad marginal.
Por otro lado, el trabajo colectivo o grupal con el álbum familiar puede tener la ventaja de sacar a la luz, las historias no contadas, negadas o no visibles de cierto tipo de vidas, es decir, hacer visibles las “existencias de aquellos cuyas formas de conocer y de ver el mundo rara vez son tenidas en cuenta, y mucho menos celebradas, en las expresiones de una cultura hegemónica” (Kuhn 2013).
PLANEJAMENTO TRIBUTARIO: ESTUDO EM UMA EMPRESA DE TRANSPORTE DE CARGA E COMÉRCIO VAREJISTA DE COMBUSTÍVEIS
Authors: Schuh Clari , Bernardi Cidonia , Sousa Marco Aurélio Batista de 
Published: October 2022

Atualmente, um dos custos mais significativos nas empresas brasileiras é a elevada carga tributária, o que pode impedir sua sustentabilidade e crescimento. Neste contexto, o objetivo do estudo foi verificar qual o tipo de tributação no âmbito Federal representa menor ônus tributário para uma empresa de transporte de carga e comércio varejista de combustíveis, levando em consideração os dados de 2015. Deste modo, foram levantados os dados junto à empresa e escritório contábil, e calculados os tributos pelo Simples Nacional, Lucro Presumido e Lucro Real. Em termos metodológicos, a pesquisa quanto ao levantamento de dados, se classifica como um estudo de caso, para o qual se utilizou da pesquisa bibliográfica e documental. Como estudo de caso, a abordagem do problema foi qualitativa e a pesquisa foi de natureza descritiva. Os resultados alcançados evidenciam que o regime de tributação menos oneroso para a empresa baseado nos dados de 2015, assim como na projeção para 2017 é o Lucro Real Anual.
Palavras-Chave: Lucro real. Lucro presumido. Planejamento tributário.

Abstract: Currently, one of the most significant costs in Brazilian companies is the high tax burden, which can impede their sustainability and growth. In this context, the objective of the study was to verify which type of taxation at the Federal level represents the lowest tax burden for a cargo transport company and retail fuel trade, taking into account the 2015 data. to the company and accounting office, and the taxes calculated by Simples Nacional, Presumed Profit and Actual Profit. In methodological terms, the research regarding data collection is classified as a case study, for which bibliographic and documentary research was used. As a case study, the approach to the problem was qualitative and the research was descriptive in nature. The results achieved show that the least onerous tax regime for the company based on 2015 data, as well as on the projection for 2017, is the Annual Real Profit.
Keywords: Real profit. Presumed profit. Tax planning.
Revegetasi Lahan Miring dengan Pola Agroforestri Tanaman Unggulan Lokal untuk Mengurangi Erosi Tanah dan Peningkatan Ekonomi Masyarakat di Desa Arga Indah I, Bengkulu Tengah
Authors: Senoaji Gunggung , Hidayat M. Fajrin , Anwar Guswarni , Lukman Agung Hasan , Susanti Elvi 
Published: October 2022

Kondisi lahan pertanian di Desa Arga Indah I, Kec. Pagar Jati, Bengkulu Tengah didominasi oleh topografi miring. Hal ini memerlukan pengelolaan lahan yang tepat agar mampu memberikan produksi pertanian yang berkelanjutan. Oleh karena itu, pemeliharaan kualitas tanah melalui pencegahan erosi untuk mempertahankan produktivitas lahan penting dilakukan. Kegiatan ini memperkenalkan teknik pengelolaan lahan dengan melakukan revegetasi lahan miring melalui pola panam agroforestri dengan tanaman unggulan lokal (Durian Bentara dan pala). Tujuan dari kegiatan ini adalah agar masyarakat mengetahui teknik pengolahan lahan miring yang dapat memberikan keuntungan ekonomi dan sekaligus mengurangi erosi tanah. Metode yang digunakan adalah survei, penyuluhan, dan demonstrasi. Penyuluhan dilakukan secara komprehensif sebagai upaya persiapan untuk pembuatan demplot. Demonstrasi dilakukan sebagai praktik pembuatan demplot. Hasil kegiatan menunjukkan bahwa masyarakat menjadi tahu dan menambah wawasan tentang teknik pengelolaan lahan miring dengan menanam tanaman unggulan lokal pada lahan pertaniannya melalui sistem agroforestri. Masyarakat desa juga mulai mengetahui bahwa Durian Bentara merupakan tanaman unggulan lokal yang dapat dibudidayakan sebagai salah satu sumber pendapatan masyarakat dan berperan juga sebagai sarana perlindungan lingkungan tanah.
Pembuatan Obat Sediaan Selama Pendemi COVID-19 Bagi Keluarga SMA Negeri 8 Kota Bengkulu Sebagai Bantuan S2 Kimia Universitas Bengkulu
Authors: Putranto Agus M.H , Widiyati Eni , Gustian Irfan , Sutanto Teja Dwi 
Published: October 2022

Pengabdian Pada Masyarakat dari Dana Bantuan Pengabdian S2 Kimia tahun 2020 berjudul “Pembuatan Sediaan Obat Sederhana Bagi Keluarga Besar SMA Negeri 8 Kota Bengkulu” telah dilaksanakan pada tanggal 8 Desember 2020. Metode yang dipergunakan pada pengabdian ini meliputi ceramah, diskusi dan praktik pembuatan obat sederhana, meliputi pembuatan sediaan obat herbal untuk pengobatan Covid-19 dari daun muda tanaman sungkai. Setelah dilakukan pengabdian berupa pelatihan pembuatan obat sederhana dan dari hasil evaluasi dapat disarikan bahwa, para guru, tenaga ke pendidikan dan siswa SMA.N 8 Bengkulu, sangat antusias selama pelatihan pengabdian, dibuktikan dengan banyak nya pertanyaan yang muncul saat pelatihan, dari peserta pengabdian ini. Dari hasil evaluasi pelaksanaan pengabdian ini diketahui bahwa pengabdian ini sangat menarik dan bermanfaat bagi keluarga besar SMA Negeri 8 Kota Bengkulu. Setelah selesai pengabdian ini para peserta menjadi tahu cara pembuatan sediaan obat sederhana yang sangat bermanfaat bagi keluarga besar SMA.N 8 Kota Bengkulu. Kata kunci: Sediaan obat; Herbal; Covid-19
SISTEM INFORMASI PENJUALAN PETI MATI BERBASIS WEB DI CV. GEOJAYA NUSANTARA
Authors: Nababan Joko Priono , Dari Wulan 
Published: October 2022

Abstract—Sales is an activity that connects customers with sellers through a product or service offered to produce something that is mutually beneficial for both parties. So for that we need a system so that sales transactions can run effectively and efficiently, for example by using a sales information system. CV. Geojaya Nusantara is a company engaged in the sale of coffins. The existing sales system in CV. Currently, Geojaya Nusantara is still carried out conventionally, such as customers who want to buy their products via phone calls or also through messaging applications such as the WhatsApp application. Then the incoming sales data is still done manually, as recorded in a sales book. Therefore, with these problems, a web-based application is needed to support the sales system which aims to simplify all transaction processes, because it can be done anytime and anywhere. The research method used is by conducting direct observations and interviews with employees or shop owners. As for the software development method used is the waterfall method and the programming language used in making the website itself is PHP, HTML, CSS, and JQuery, and for the database it uses MySQL. The expected results in this web-based coffin sales information system at CV Geojaya Nusantara, are expected to be a solution to overcome the problems encountered due to the conventional system, and can also overcome errors in the sales recording input process.

Keywords: coffin sales, information system, web-based
Investigation of the Cultural Competence Levels of Diabetes Nurses
Authors: ÇINAR Derya , OLGUN Nermin , KOYUNCU Aynur 
Published: October 2022

Objective: It is important for nurses to have cultural competence in order to keep up with the cultural diversity brought by globalization. In this study, we aim to examine the cultural competence levels of diabetes nurses in diabetes education and care in accordance with the cultural characteristics of individuals with diabetes.
Methods: This study was conducted in a cross-sectional descriptive type with 183 diabetes nurses between September 15 and December 15, 2020 in Turkey. The data were collected using the Introductory Information Form and the Nurse Cultural Competence Scale.
Results: We determine that almost all of the diabetes nurses had cultural competence above the average. We find that having a postgraduate degree from diabetes nurses, receiving cultural education before, and having a diabetes nurse experience of 6 years or more affected the cultural competence levels (p
Synthesis of Nanoparticles Loading Indenopyrazole Derivatives and Evaluation of Biological Features
Authors: DOĞAN Murat , KOÇYİĞİT Ümit Muhammet , GEZEGEN Hayreddin 
Published: October 2022

Objective: In this study, it was aimed to prepare nanoparticle formulations using chitosan, a cationic natural polymer, and tripoly phosphate, and to perform mechanical characterization and in vitro cell culture studies. In addition, the cytotoxic effects of nanoparticles containing indenopyrazol derivatives against human glioma cells (C6) and human cervical cancer cells (HeLa) were investigated.
Methods: Within the scope of the study, nanoparticles containing indenopyrazole derivative were prepared and characterization of particle size, zeta potential and morphological properties were performed. XTT cytotoxicity test was applied to evaluate the antiproliferative activities of nanoparticles containing these components.
Results: Particle size, zeta potential and morphological properties of nanoparticles were observed to be suitable for application. In vitro cell culture studies showed that nanoparticles containing indenopyrazol derivatives showed better cytotoxic effects in both cell lines.
Conclusion: The results showed that the mechanical properties of nanoparticles containing indenopyrazol derivatives are suitable and can be applied in anticancer activity studies.
ANALISA PENERAPAN DISASTER RECOVERY PLAN PADA DATA CENTER PERUSAHAAN
Authors: Makpul Zulkarnain Bin Muhammad 
Published: October 2022

Disaster recovery plan atau DRP merupakan sebuah perencanaan yang digunakan unutk menjalankan operasional dalam kondisi terjadi gangguan. Saat ini perusahaan tidak mempunyai gambaran tentang keberhasilan implementasi DRP. Dengan melakukan analisa implementasi disaster recovery plan pada data center perusahaan, maka peneliti akan mengetahui apakah implementasi DRP sudah dilakukan dengan benar, apabila terjadi bencana atau gangguan, perusahaan masih bisa menjalakan operasionalnya atau bisa juga mengembalikan system dengan waktu yang cepat. Penelitian ini menggunakan metode deskriptif kualitatif. Sumbar data diambil dari pengamatan langsung, melakukan pengecekan dokument serta melakukan wawancara. Hasil dari analisa dan pembahasan, penulis akan mengetahui tentang beberapa kegiatan atau proses DRP yang telah dilakukan dengan benar dan ada juga beberapa kegiatan atau proses yang harus menjadi fokus perbaikan.
Facile preparation of Ti3C2Tx sheets by selectively etching in a H2SO4/H2O2 mixture
Authors: Tian Zhengshan , Tian Hao , Cao Kesheng , Bai Suzhen , Peng Qinlong , Wang Yabo , Zhu Qiuxiang 
Published: October 2022

MXenes and MXene-based composite materials have potential applications in a wide range of areas due to their unique physical and chemical characteristics. At present, it is still a major challenge to develop a simple, safe, and efficient route to prepare MXenes without using fluorinated etchants. Herein, we design a facile method to prepare Ti3C2Tx MXene sheets by selectively etching Ti3AlC2 powders in an aqueous diluted H2SO4 solution with H2O2 as an oxidant. In a system of H2SO4 and H2O2, an aqueous H2SO4 solution with a concentration of 6 mol/L is a strongly acidic medium with no volatility, and 30% H2O2 acts as a strong green oxidizer without harmful by-products. The experimental process is safe and convenient to conduct in a beaker under a water bath of 40°C. The etching process can be completed in 1 h under the air atmosphere conditions. The experimental results confirmed that the etched Ti3AlC2 powders can be successfully separated into Ti3C2Tx nanosheets under ultrasound treatment without using any intercalation agent. The relevant etching mechanism is may be attributed to the synergy effect of H2SO4 and H2O2, which triggers sequential selective etching of Al layers from the Ti3AlC2 phase. It may provide a new green way to prepare MXene-based materials without using toxic HF or HF-containing etchants.
Combining bulk RNA-sequencing and single-cell RNA-sequencing data to reveal the immune microenvironment and metabolic pattern of osteosarcoma
Authors: Huang Ruichao , Wang Xiaohu , Yin Xiangyun , Zhou Yaqi , Sun Jiansheng , Yin Zhongxiu , Zhu Zhi 
Published: October 2022

Background: Osteosarcoma (OS) is a kind of solid tumor with high heterogeneity at tumor microenvironment (TME), genome and transcriptome level. In view of the regulatory effect of metabolism on TME, this study was based on four metabolic models to explore the intertumoral heterogeneity of OS at the RNA sequencing (RNA-seq) level and the intratumoral heterogeneity of OS at the bulk RNA-seq and single cell RNA-seq (scRNA-seq) level.Methods: The GSVA package was used for single-sample gene set enrichment analysis (ssGSEA) analysis to obtain a glycolysis, pentose phosphate pathway (PPP), fatty acid oxidation (FAO) and glutaminolysis gene sets score. ConsensusClusterPlus was employed to cluster OS samples downloaded from the Target database. The scRNA-seq and bulk RNA-seq data of immune cells from GSE162454 dataset were analyzed to identify the subsets and types of immune cells in OS. Malignant cells and non-malignant cells were distinguished by large-scale chromosomal copy number variation. The correlations of metabolic molecular subtypes and immune cell types with four metabolic patterns, hypoxia and angiogenesis were determined by Pearson correlation analysis.Results: Two metabolism-related molecular subtypes of OS, cluster 1 and cluster 2, were identified. Cluster 2 was associated with poor prognosis of OS, active glycolysis, FAO, glutaminolysis, and bad TME. The identified 28608 immune cells were divided into 15 separate clusters covering 6 types of immune cells. The enrichment scores of 5 kinds of immune cells in cluster-1 and cluster-2 were significantly different. And five kinds of immune cells were significantly correlated with four metabolic modes, hypoxia and angiogenesis. Of the 28,608 immune cells, 7617 were malignant cells. The four metabolic patterns of malignant cells were significantly positively correlated with hypoxia and negatively correlated with angiogenesis.Conclusion: We used RNA-seq to reveal two molecular subtypes of OS with prognosis, metabolic pattern and TME, and determined the composition and metabolic heterogeneity of immune cells in OS tumor by bulk RNA-seq and single-cell RNA-seq.
Impacts of hypoxia on the mesozooplankton community structure in a semi-enclosed bay
Authors: Lee Eun Hye , Choi Seo Yeol , Seo Min Ho , Soh Ho Young 
Published: October 2022

Gamak Bay is frequently affected by hypoxia in summer. Therefore, this study aimed to examine the effect of hypoxia on the mesozooplankton community of this region. Mesozooplankton samples were obtained biweekly (28 times) at a hypoxic station (inner bay) and a normoxic station (middle bay) using a conical net (mesh size 200 μm; mouth diameter 30 cm) from April 2020 to April 2021. In the inner bay, hypoxia was observed a total of five times between early June and late September, whereas no instances of hypoxia were detected in the middle bay. During the hypoxic period, mesozooplankton abundance was higher in the inner bay than the middle bay (p &lt; 0.05). During the normoxic period, there was no difference between the inner bay and the middle bay (p &gt; 0.05). The dominant species in the hypoxic period were three species of cladocerans (Pleopis polyphemoides, Pseudoevadne tergestina, Penilia avirostris) and the copepod Acartia sinjiensis. The abundance of cladocerans was higher in the inner bay, and that of A. sinjiensis was higher in the middle bay (p &lt; 0.05). In addition to water temperature, salinity, and size-fractionated Chl-a concentration, mesozooplankton abundance was also significantly correlated with the bottom DO concentration. Collectively, our findings suggest that hypoxia can affect mesozooplankton abundance and occurrence times.