bluuebunny/crossref_metadata_2025_split huggingface dataset:
Internet of things network intrusion detection model based on quantum artificial fish group and fuzzy kernel clustering algorithm
Authors: Zhang Jinfeng , Zhang Dongdong 
Published: March 2022

AbstractThe application of internet of things (IoT) devices in 5G/B5G has benefited many industries, such as automated production, smart agriculture and autopilot, and has provided access to billions of smart devices. However, the rapid growth of IoT devices has also brought network security issues. The purpose of this paper is to study the network intrusion detection model based on quantum artificial fish population and fuzzy kernel clustering algorithm. In this paper, the network intrusion detection model based on traditional fuzzy C‐means (FCM) clustering has poor classification effect and is prone to local extremum. A semi‐supervised fuzzy kernel–clustering algorithm based on quantum artificial fish group is proposed. The algorithm adopts a small amount of tag data and many unknown tag data to generate the classification of network intrusion detection and constructs a new objective function of FCM algorithm by means of kernel distance. In the simulation experiment of KDD Cup 99 network intrusion detection data, compared with the intrusion detection model based on FCM, particle swarm optimization‐FCM, the detection rate of the proposed algorithm in the known attack and unknown attack is 92.5% and 84.9%, respectively. The results show that the proposed intrusion detection algorithm has better detection rate.
Managed aquifer recharge site assessment with electromagnetic imaging: Identification of recharge flow paths
Authors: Pepin Karissa , Knight Rosemary , Goebel‐Szenher Meredith , Kang Seogi 
Published: March 2022

AbstractSurface spreading recharge, the intentional flooding of the ground surface to replenish a groundwater system, is one approach used to mitigate groundwater overdraft in California's Central Valley (CV). Choosing appropriate sites for surface spreading recharge, in regard to the sites’ ability to convey water from the ground surface to the desired recharge depth, can be challenging because of limited knowledge of the properties of the subsurface. In this study, we present an approach for using a towed time‐domain electromagnetic (tTEM) imaging method to develop three‐dimensional (3D) models of sediment type, map potential flow paths through the subsurface, and evaluate sites for surface spreading. We began with tTEM data from seven sites in the CV along with an existing resistivity‐to‐sediment type transform. We leveraged geostatistical methods to generate multiple 3D models of binary (flow and no‐flow) sediment type from the tTEM data. We then developed two metrics to assess the quality of sites for recharge: (a) the depth to the shallowest no‐flow unit beneath each point at the surface and (b) preferential flow paths lengths measured by finding the shortest distance through connected flow units between surface points and the desired depth. We explored how these metrics can be used to identify optimal areas within a site, then developed a way to compare and assess the relative suitability of each site using the decay in the number of vertical flow paths as a function of depth. Our methods can be used to rapidly identify potential sites for surface spreading recharge.
Management of osteoarthritis: From drug molecules to nano/micromedicines
Authors: Di Francesco Martina , Fragassi Agnese , Pannuzzo Martina , Ferreira Miguel , Brahmachari Sayanti , Decuzzi Paolo 
Published: March 2022

AbstractWith the change in lifestyle and aging of the population, osteoarthritis (OA) is emerging as a major medical burden globally. OA is a chronic inflammatory and degenerative disease initially manifesting with joint pain and eventually leading to permanent disability. To date, there are no drugs available for the definitive treatment of osteoarthritis and most therapies have been palliative in nature by alleviating symptoms rather than curing the disease. This coupled with the vague understanding of the early symptoms and methods of diagnosis so that the disease continues as a global problem and calls for concerted research efforts. A cascade of events regulates the onset and progression of osteoarthritis starting with the production of proinflammatory cytokines, including interleukin (IL)‐1β, IL‐6, tumor necrosis factor (TNF)‐α; catabolic enzymes, such as matrix metalloproteinases (MMPs)‐1, ‐3, and ‐13, culminating into cartilage breakdown, loss of lubrication, pain, and inability to load the joint. Although intra‐articular injections of small and macromolecules are often prescribed to alleviate symptoms, low residence times within the synovial cavity severely impair their efficacy. This review will briefly describe the factors dictating the onset and progression of the disease, present the current clinically approved methods for its treatment and diagnosis, and finally elaborate on the main challenges and opportunities for the application of nano/micromedicines in the treatment of osteoarthritis. Thus, future treatment regimens will benefit from simultaneous consideration of the mechanobiological, the inflammatory, and tissue degradation aspects of the disease.This article is categorized under:
Nanotechnology Approaches to Biology > Nanoscale Systems in Biology
Implantable Materials and Surgical Technologies > Nanotechnology in Tissue Repair and Replacement
Gendered Migrations and Conceptual Approaches: Theorising and Researching Mobilities
Authors: Christou Anastasia , Kofman Eleonore 
Published: March 2022

AbstractWhile the repetitive rhetoric of ‘discovering’ women as active agents in mobility decisions, plans and the execution of such, might have had a major contribution in filling an important lacuna in migration studies literature several decades ago now (Morokvasic, 1984; Kofman, 1999), there are a number of analytical problems with continuing claims that seem to either conflate ‘gender’ with women or tend to nearly essentialise the ‘feminization of migration’ in reflecting discursive stereotypes. In the latter case, gendered migration research requires taking on board the historicity and local embeddedness of particular case studies which should clearly frame socio-political and development strategies when conducting studies to understand women migrants and female migration (Cornwall et al., 2008; Dannecker & Sieveking, 2009; Amelina & Lutz, 2019). This perspective becomes clear in the following sections and in the box included in this chapter where we include exemplifications from case studies and our own research findings.
The effects of pelvic ring injuries on quality of life, physical, and mental health: results of a 2-year prospective cohort study
Authors: Banierink Hester , ten Duis Kaj , Meesters Anne M. L. , Trouwborst Nymke M. , Heineman Erik , Wendt Klaus W. , Ploegmakers Joris J. W. , Reininga Inge H. F. , IJpma Frank F. A. 
Published: March 2022

Abstract
Purpose
Pelvic ring injuries are known to affect the patients’ daily life in terms of physical functioning and quality of life (QoL). Still, prospective studies on the patient’s perception over the first 2 years of rehabilitation are lacking. Therefore, patients cannot be properly informed about whether or when they will return to their pre-existing level of physical functioning and QoL.

Methods
A prospective longitudinal cohort study was performed over a 4-year period including all consecutive patients above 18 years who sustained a pelvic ring injury in a level 1 trauma center. Validated patient-reported outcome measures (PROMs) were used to assess physical functioning (SMFA) and QoL (EQ-5D) at baseline (recalled pre-injury score), 6 weeks, 3 months, 6 months, 1 year and 2 years after the injury. It was assessed whether patients had fully recovered by comparing follow-up scores to baseline PROMs. Binary logistic regression analysis was used to identify independent predictors for patients who did not fully recover. Most experienced difficulties at 3 months and 1 year were identified by analyzing the highest reported scores on individual items of the SMFA.

Results
A total of 297 patients with a pelvic ring injury were identified of which 189 were eligible for follow-up and 154 (82%) responded. Median SMFA function score at 3 months, 1 and 2 years was 70, 78 and 88, respectively, compared to 96 out of 100 before the injury. Median SMFA bother score was 67, 79 and 88, respectively. Median EQ-5D score at 3 months, 1 and 2 years was 0.61, 0.81 and 0.85, respectively, compared to 1 (maximum achievable) before the injury. After 1 and 2 years of follow-up, 61% and 75% of the patients fully “recovered” in physical functioning and 52% and 71% fully recovered in terms of QoL. Female gender and high-energy trauma were independent predictors for not fully recovering after 1 year. After 3 months of follow-up, 54% of patients reported severe difficulties with recreational activities, whereas after 1 year, most experienced difficulties (31% of patients) concerned heavy house or yard work. Moreover, after 3 months and 1 year, 44% and 27% of patients reported feeling physically disabled.

Conclusion
Pelvic ring injuries have a large impact on the patients’ daily life in the first 2 years of rehabilitation. Directly after the injury, physical functioning and QoL decrease strongly but then gradually improve over a 2-year period with about 75% of patients fully recovering. Female gender and high-energy trauma are shown to be independent predictors for not fully recovering. After 3 months, patients experience difficulties with both the physical and mental effects of the injury which continue to be present after 1 year.
Grouping of chemicals into mode of action classes by automated effect pattern analysis using the zebrafish embryo toxicity test
Authors: Teixidó E. , Kieβling T. R. , Klüver N. , Scholz S. 
Published: March 2022

AbstractA central element of high throughput screens for chemical effect assessment using zebrafish is the assessment and quantification of phenotypic changes. By application of an automated and more unbiased analysis of these changes using image analysis, patterns of phenotypes may be associated with the mode of action (MoA) of the exposure chemical. The aim of our study was to explore to what extent compounds can be grouped according to their anticipated toxicological or pharmacological mode of action using an automated quantitative multi-endpoint zebrafish test. Chemical-response signatures for 30 endpoints, covering phenotypic and functional features, were generated for 25 chemicals assigned to 8 broad MoA classes. Unsupervised clustering of the profiling data demonstrated that chemicals were partially grouped by their main MoA. Analysis with a supervised clustering technique such as a partial least squares discriminant analysis (PLS-DA) allowed to identify markers with a strong potential to discriminate between MoAs such as mandibular arch malformation observed for compounds interfering with retinoic acid signaling. The capacity for discriminating MoAs was also benchmarked to an available battery of in vitro toxicity data obtained from ToxCast library indicating a partially similar performance. Further, we discussed to which extent the collected dataset indicated indeed differences for compounds with presumably similar MoA or whether other factors such as toxicokinetic differences could have an important impact on the determined response patterns.
A new model for predicting the winner in tennis based on the eigenvector centrality
Authors: Arcagni Alberto , Candila Vincenzo , Grassi Rosanna 
Published: March 2022

AbstractThe use of statistical tools for predicting the winner in tennis matches has enjoyed an increase in popularity over the last two decades and, currently, a variety of methods are available. In particular, paired comparison approaches make use of latent ability estimates or rating calculations to determine the probability that a player will win a match. In this paper, we extend this latter class of models by using network indicators for the predictions. We propose a measure based on eigenvector centrality. Unlike what happens for the standard paired comparisons class (where the rates or latent abilities only change at timetfor those players involved in the matches at timet), the use of a centrality measure allows the ratings of the whole set of players to vary every time there is a new match. The resulting ratings are then used as a covariate in a simple logit model. Evaluating the proposed approach with respect to some popular competing specifications, we find that the centrality-based approach largely and consistently outperforms all the alternative models considered in terms of the prediction accuracy. Finally, the proposed method also achieves positive betting results.
The heterogeneous effects of the great recession on informal care to the elderly
Authors: Carro Jesús M. , Pronkina Elizaveta 
Published: March 2022

AbstractThis paper studies the role of unobserved factors to measure the impact of the economic downturn on informal care availability to the elderly in Europe. We use the Survey of Health, Ageing and Retirement in Europe (SHARE), which allows controlling for socio-demographic variables. Our results show that the impact of the Great Recession on care receipt depends not only on observed, but also on unobserved characteristics. For 21% of the sample, the effect is three to four times larger than the average effect for the entire sample. For 57% of the sample, there is no effect of the economic crisis, and this is related to unobservable factors. In our estimation process, we are able to characterize how this unobserved heterogeneity correlates with the observable variables. Moreover, we show that if the unobserved heterogeneity in the effect of the crisis is ignored, then we are not able to capture that there is no effect for more than half of the individuals, even if we allow for unobserved heterogeneity in the intercept of the model and for the heterogeneous effect of the crisis based on observables.
Parent-reported Early Atypical Development and Age of Diagnosis for Children with Co-occurring Autism and ADHD
Authors: Sainsbury Willow J. , Carrasco Kelly , Whitehouse Andrew J. O. , Waddington Hannah 
Published: March 2022

AbstractAutism and attention-deficit/hyperactivity disorder (ADHD) often co-occur. This survey of 288 New Zealand parents of children diagnosed with autism (n = 111), ADHD (n = 93), or both conditions (n = 84), examined the relations between age of diagnosis and early atypical development, the age specialist consultation was needed and types of specialists seen. Co-occurring autism and ADHD was associated with an earlier ADHD diagnosis and a later autism diagnosis. Parents of children with both diagnoses reported less atypical development in language and social behaviours compared to parents of children of autism, and this co-occurring group also experienced longer wait times to diagnosis, and saw more types of specialists prior to a diagnosis, than those with autism.
Examining Temporality and Difference: an Intensive Approach to Understanding Medieval Rural Settlement
Authors: Jervis Ben 
Published: March 2022

AbstractA new theoretical approach to medieval rural settlement, built on the concept of intensity, is proposed. It is argued that analysing settlements as intensive spaces creates new opportunities to explore the emergence of difference in medieval lived experience. The approach is intended to overcome the challenges posed by approaches to medieval architecture framed by binary divisions (e.g. inside/outside). Drawing on posthuman thought, it is argued that such divisions constrain the understanding of how and why difference emerged in the past. The paper advances this approach through its application to the study of house construction and domestic economy in the medieval village of Hangleton, England. It is proposed that difference emerges as everyday practices are performed in constantly changing material environments, generating situationally grounded but varied experiences of rurality. Rather than being subject to macro-scale economic processes, this approach allows us to understand historical change as a patchwork of localised interactions which overflowed the bounds of communities or regions.
“Let’s build an Anscombe box”: assessing Anscombe’s rebuttal of the statistics objection against indeterminism-based free agency
Authors: Müller Thomas 
Published: March 2022

AbstractTowards the end of her famous 1971 paper “Causality and Determination”, Elizabeth Anscombe discusses the controversial idea that “ ‘physical haphazard’ could be the only physical correlate of human freedom of action”. In order to illustrate how the high-level freedom of human action can go together with micro-indeterminism without creating a problem for micro-statistics, she provides the analogy of a glass box filled with minute coloured particles whose micro-dynamics is subject to statistical laws, while its outside reliably displays a recognisable variation of a certain image created by an external cause. Anscombe’s example is somewhat enigmatic, and she provides no details to support its viability. In this paper we discuss the context of Anscombe’s analogy, and we provide basics of the theory and practice of building an Anscombe box.
Demystifying the myth of sensation: Wilfrid Sellars’ adverbialism reconsidered
Authors: Corti Luca 
Published: March 2022

AbstractThis paper reconstructs and defends a Sellarsian approach to “sensation” that allows us to avoid mythological conceptions of it. Part I reconstructs and isolates Sellars’s argument for “sensation,” situating his adverbial interpretation of the notion within his broader theory of perception. Part II positions Sellars’s views vis-à-vis current conversations on adverbalism. In particular, it focuses on the Many Property Problem, which is traditionally considered the main obstacle to adverbialism. After reconstructing Sellars’s response to this problem, I demonstrate that his position is compatible with some current strategies to solving it and can be developed along similar lines. Finally, part III addresses how a Sellarsian adverbial approach productively accounts for the phenomenal properties of experience often understood to fall under the notion of “sensation”. The paper therefore shows how isolating Sellars’s argument can yield a non-problematic conception of sensation. Indeed, the argument on which I focus offers a form of direct realism compatible with recent forms of “new adverbialism”. Although my view remains Sellarsian, to defend it I maintain that some Sellarsian claims about sensation should be resisted as not logically entailed by his argument.
Quantum Technologies and Society: Towards a Different Spin
Authors: Coenen Christopher , Grinbaum Alexei , Grunwald Armin , Milburn Colin , Vermaas Pieter 
Published: March 2022

AbstractDue primarily to technological advances over the last decade, quantum research has become a key priority area for science and technology policy all over the world. With this manifesto, we wish to prevent quantum technology from running into fiascos of implementation at the interface of science and society. To this end, we identify key stumbling blocks and propose recommendations.
The Experience of European Researchers in China: A Comparative Capital Advantage Perspective
Authors: Braun Střelcová Andrea , Cai Yuzhuo , Shen Wei 
Published: March 2022

AbstractThis paper unfolds a “black box” concerning European researchers working in China, an emerging phenomenon as an outcome of European and Chinese international research collaboration. China’s rapid economic growth has created plentiful career opportunities in research and innovation, attracting mainly returning Chinese but also non-Chinese researchers. While emerging research has brought attention to the individual experiences of the latter group, this work has been hampered by a lack of conceptual frameworks, as well as empirical knowledge regarding these migrants’ motivations, job satisfaction, and career prospects. This article attempts to bridge this research gap by focusing on European researchers working in Chinese universities. It develops a novel analytical framework that integrates insights from the push–pull framework and Bourdieu’s conceptualization of capital and applies this framework in a qualitative investigation of China-based European researchers. This analysis shows, first, that significant capital gains exist for natural scientists, as opposed to social scientists, in China, as the former operates in a more internationalized, better-funded, and less politically controlled environment. Second, it demonstrates that European researchers’ migration journeys in China remain predominantly temporary, as their initial advantages tend to fade away over time. Finally, this article finds that European researchers’ reasons for leaving China are connected to challenges beyond the workplace, yet their stay in China becomes an important step in increasing their competitiveness in the global academic labor market.
Vortex Merger in Shallow Water Model
Authors: Sun Wen-Yih , Oh Tae-Jin 
Published: March 2022

AbstractAn inviscid, nonlinear shallow water model is applied to study the formation of filaments and merging of potential vorticity (PV, π). We confirm that misalignment of vorticity with the streamlines is crucial to merger. Flow creates positive PV tendency (πt) on the lee side of π ridge, which increases the angle between streamlines and PV contours and the efficiency of vorticity transport along the parallel but oppositive direction in the positive quadrants of πt. So, the vortices move closer while rotating around each other. Filamentation starts as weak vorticity shatters from the outer edge of vortex core. The filament grows and rotates around the cores, but shows little effects to positive PV advection or vortex merging in the inner core, evidenced by the steady core area integrated PV trends. Consecutive PV transfer from lower to higher interval levels are observed during merger process while elongated filamentation is dissolving into the lower level PV regime. The vortices never merge when negative πt prevails between two vortices. Distance between the vortex cores show direct correspondence to positive πt between them. Hence, the advance of positive πt provides a simple mechanism of merging. The Rossby radius of deformation (LD) is confirmed to be another strong indicator for vortex pair merger where LD comparable or smaller than the initial vortex core separation length scale makes merger more likely due to geostrophic adjustment. The Rossby number (Ro) affected the overall flow interaction speed speed when LD is fixed.
Gas-discharge induced flash sintering of YSZ ceramics at room temperature
Authors: Zhu Yuchen , Zhou Hongyang , Huang Rongxia , Yan Nianping , Wang Xilin , Liu Guanghua , Jia Zhidong 
Published: March 2022

AbstractThis is the first study to conduct the flash sintering of 3 mol% yttria-stabilized zirconia (3YSZ) ceramics at room temperature (25 °C) under a strong electric field, larger than 1 kV/cm. At the standard atmospheric pressure (101 kPa), the probability of successful sintering is approximately half of that at low atmospheric pressure, lower than 80 kPa. The success of the proposed flash sintering process was determined based on the high electric arc performance at different atmospheric pressures ranging from 20 to 100 kPa. The 3YSZ samples achieved a maximum relative density of 99.5% with a grain size of ∼200 nm. The results showed that as the atmospheric pressure decreases, the onset electric field of flash sintering decreases, corresponding to the empirical formula of the flashover voltage. Moreover, flash sintering was found to be triggered by the surface flashover of ceramic samples, and the electric arc on the sample surfaces floated upward before complete flash sintering at overly high pressures, resulting in the failure of flash sintering. This study reveals a new method for the facile preparation of flash-sintered ceramics at room temperature, which will promote the application of flash sintering in the ceramic industry.