bluuebunny/crossref_metadata_2025_split huggingface dataset:
ENGLISH FOR MEDIA LITERACY FOR EDUCATORS (EML-E) (MATERIAL RESUME AND REVIEW OF THE ONLINE PROFESSIONAL ENGLISH NETWORK (OPEN) BY GEORGE MASON UNIVERSITY)
Authors: Misnawati Misnawati 
Published: August 2022

People are often discussing the media these days. In personal, professional, and educational contexts, social media, mass media, and media bias are regularly debated. Media literacy can understand, critique, and create media messages, while media messages are communicated via traditional or digital media. English Media Literacy (EML) analyses, provides and embeds media literacy as English language teaching in class. Educators realized in the late 20th century that they need to help their students "read" or "understand" different types of texts to guide students with a good mindset and acquire media messages as a skill and knowledge to become successful citizens of the 21st century. The new technologies and media started happening in the early 2000s or the beginning of the 21st century. This article served as material resume and review for the English for Media Literacy for Educators (EML-E) course as one of The Online Professional English Network (OPEN) By George Mason University. It is sponsored by the U.S. Department of State with funding provided by the U.S. government and administered by FHI 360. As media literacy is essential, this material resume is served by the author to cascade her new knowledge about this topic to increase its benefit. This paper will discuss five elements, they are: 1) Introduction to English for Media Literacy for Educators; 2) Approaches and Strategies for Media Literacy Education; 3) Managing Student Media Consumption and Production; 4) Language for Teaching English for Media Literacy, and 5) English for Media Literacy Unit Planning..
Is the Revision Rate for Femoral Neck Fracture Lower for Total Hip Arthroplasty Than for Hemiarthroplasty?
Authors: Hoskins Wayne , Corfield Sophia , Lorimer Michelle , Peng Yi , Bingham Roger , Graves Stephen E. , Vince Kelly G. 
Published: August 2022

Background:When arthroplasty is indicated for a femoral neck fracture (FNF), it is unclear whether total hip arthroplasty (THA) or hemiarthroplasty (HA) is best. This study compares data from the Australian Orthopaedic Association National Joint Replacement Registry using contemporary surgical options.Methods:Patients from 60 to 85 years old who were treated with arthroplasty for FNF, between September 1999 and December 2019, were included if the femoral stems were cemented. Only THAs with femoral heads of ≥36 mm or dual-mobility articulations were included. Patients who had monoblock HA were excluded. Rates of revision for all aseptic failures and dislocation were compared. Competing risks of revision and death were considered using the cumulative incidence function. Subdistribution hazard ratios (HRs) for revision or death from a Fine-Gray regression model were used to compare THA and HA. Interactions of procedure with age group and sex were considered. Secondary analysis adjusting for body mass index (BMI) and American Society of Anesthesiologists (ASA) classification was also considered.Results:There were 4,551 THA and 29,714 HA procedures included. The rate of revision for THA was lower for women from 60 to 69 years old (HR = 0.58 [95% confidence interval (CI), 0.39 to 0.85]) and from 70 to 74 years old (HR = 0.65 [95% CI, 0.43 to 0.98]) compared with HA. However, women from 80 to 85 years old (HR = 1.56 [95% CI, 1.03 to 2.35]) and men from 75 to 79 years old (HR = 1.61 [95% CI, 1.05 to 2.46]) and 80 to 85 years old (HR = 2.73 [95% CI, 1.89 to 3.95]) had an increased rate of revision when THA was undertaken compared with HA. There was no difference in the rate of revision for dislocation between THA and HA for either sex or age categories.Conclusions:When contemporary surgical options for FNF are used, there is a benefit with respect to revision outcomes for THA in women who are <75 years old and a benefit for HA in women who are ≥80 years old and men who are ≥75 years old. There is no difference in dislocation rates.Level of Evidence:TherapeuticLevel III. See Instructions for Authors for a complete description of levels of evidence.
A Comprehensive Analysis of Energy Efficiency Using Cooperative Spectrum Sensing Network
Authors: Boddukuri Naveen Kumar , Pal Debasish , Bandyopadhyay Ayan Kumar , Koley Chaitali 
Published: August 2022

Abstract
The proposed cooperative spectrum sensing (CSS) network has promising characteristics that might increase detection performance. This study focuses on identifying unknown signals in a Rayleigh fading environment using an improved energy detector (IED). The suggested network is made up of numerous cognitive radio (CR) nodes, with a number of antennas installed at each CR node and selection combining (SC) used to identify the maximum detection probability. Furthermore, the activity of the primary user (PU) is completed at the fusion centre utilizing fusion rules (FC). The closed-form of missing detection and false alarm probability was initially given elegantly. A quantitative evaluation is presented to estimate average throughput and energy efficiency and overall error rate performance is examined for single and multiple antenna situations. Simulation test-bed is developed in MATLAB, and simulations are used to evaluate throughput and energy efficiency performance with the strong backing of mathematical analysis. Finally, when compared to traditional schemes, the performance of the suggested scheme is enhanced, with OR-Rule outperforming AND-Rule.
Establishing the Taxa, Functional profile, and in-silico Ayurvedic Remedy of Microbiota implicated in West Nile Fever
Authors: Bagchi Preenon , Jovita Jemy Ratna , IA Shylesh Murthy 
Published: August 2022

Abstract
West Nile fever causing microbiome is taken in this work. Culex nigripalpus mosquito is the causative factor for West Nile Virus. Using Metatranscriptomic sequencing, identified the taxa and functional profile of the microbiome is identified. Again, the receptor genes involved in West Nile fever is taken and using computer aided drug design, the novel ligands from Ayurvedic medicinal plants Ginkgo biloba, Uncaria tomentosa, Lycoris radiate and Glycyrrhiza glabra. Further, in-vitro and in-vivo studies can be done on the selected ligands to prove their efficiency as drugs for the disease
Phantom and clinical evaluation of a new Bayesian penalized likelihood reconstruction algorithm HYPER Iterative on the image quality of 68Ga-DOTA-NOC PET/CT
Authors: Xu Lei , Cui Can , Li Rushuai , Yang Rui , Liu Rencong , Meng Qingle , Wang Feng 
Published: August 2022

Abstract
Background
Bayesian penalized likelihood (BPL) algorithm is an effective way to suppress the noise by incorporating a smooth penalty in the positron emission tomography (PET) image reconstruction process. The strength of the smooth penalty is controlled by the penalization factor. The aim was to investigate the impact of different penalization factor and acquisition time in a new BPL algorithm HYPER Iterative on the image quality of 68Ga-DOTA-NOC PET/CT. A phantom and 25 patients with neuroendocrine neoplasm underwent 68Ga-DOTA-NOC PET/CT were included. The PET data were acquired with a digital PET/CT in a list-mode and reconstructed by ordered subset expectation maximization (OSEM) and HYPER Iterative algorithm with seven penalization factors between 0.03 and 0.5 for 2 and 3 minutes-per-bed (m/b) acquisition, both including time of flight and point of spread function recovery. The contrast recovery (CR) and background variability (BV) of the phantom, SUVmean and coefficient of variation of liver (CV), and SUVmax of the lesions were measured. Image quality was ranked by two radiologists using the five-point Likert scale.
Results
The CR and BV decreases with the increased of penalization factor for four hot spheres, and HYPER Iterative 2 m/b groups with penalization factor 0.07 to 0.2 had equivalent CR and better BV performance compared to OSEM 3m/b group. The liver SUVmean was approximately equal in all reconstruction groups (range 5.95–5.97), and the liver CVs of HYPER Iterative 2 m/b and 3 m/b groups with the penalization factor of 0.1 to 0.2 were equivalent to OSEM 3 m/b group (p = 0.113–0.711 and p = 0.079–0.287), while the lesions SUVmax significantly increased 19–22% and 25% (all p < 0.001). The highest qualitative score was attained at the penalization factor of 0.2 for HYPER Iterative 2 m/b group (3.20 ± 0.52) and 3 m/b group (3.70 ± 0.36) which was comparable to or greater than OSEM 3m/b group (3.09 ± 0.36, p = 0.388 and p < 0.001).
Conclusions
HYPER Iterative algorithm with penalization factor of 0.2 resulted in higher lesion contrast and lower image noise in comparison with OSEM for 68Ga-DOTA-NOC PET/CT, which allows lower injected activity and shorter acquisition time with preserved image quality.
ECSIT is a critical factor for controlling intestinal homeostasis and tumorigenesis through regulating the translation of YAP protein
Authors: Yang Shuo , Wang Bingwei , Moynagh Paul , Wen Shuang , Liu Lu , Wu Chunyan , Ma Chanyuan , Yang Yongbing , Hu Yingchao , Ma Chunmei , Jiang Yuying 
Published: August 2022

Abstract
The intestinal epithelium is the fastest renewing tissue in mammals and its regenerative process must be tightly controlled to minimize the risk of dysfunction and tumorigenesis. The orderly expression and activation of the YAP protein is a key step in driving intestinal development and crucial for intestinal regenerative responses and homeostasis. However, the regulatory mechanisms controlling this process remain largely unknown. Here, we discovered that evolutionarily conserved signaling intermediate in Toll pathways (ECSIT), a multi-functional protein, was enriched along the crypt-villus axis. And intestinal cell-specific ablation of ECSIT results in the dysregulation of intestinal epithelial cell (IEC) differentiation accompanied with enhanced YAP protein dependent on translation thus transforming intestinal cells to early proliferative stem “-like” cell and augmenting intestinal tumorigenesis. We further revealed that loss of ECSIT impaired mitochondrial metabolism thus reprograming to amino acid-based metabolism, which results in demethylation of genes encoding the eIF4F pathway and their increased expression that further promotes selective YAP translation initiation culminating in intestinal homeostasis imbalance and tumorigenesis. We also show that the expression of ECSIT is positively correlated with the survival of patients with colorectal cancer. Together, our studies demonstrate an important role of ECSIT in maintaining optimal intestinal differentiation homeostasis and controlling the development of tumorigenesis through the regulation of YAP protein translation.
The mechanism of a humid climate on the joints of normal rats and collagen- induced arthritis rats: mutual effects on faecal metabolism and microbial diversity
Authors: Wang Dingnan , Zheng Zhili , Yu Han , Dou Dou , Gao Yining , Xu Shuang , Li Zhiming , Sun Lili , Qiu Xudong , Zhong Xianggen 
Published: August 2022

Abstract
Studies have shown that high humidity is a condition that aggravates the pain of rheumatoid arthritis (RA), but the relevant mechanism is controversial. Currently, there is a lack of animal experimental studies on high humidity as an adverse factor related to the pathogenesis of RA. We used healthy SD rats and collagen-induced arthritis (CIA) rats to investigate the effects of high humidity on arthritis in healthy rats and CIA rats. Integrated metabolomics analyses of faeces and 16S rRNA sequencing of the faecal microbiota were performed to comprehensively analyse the results and diversity of the faecal microbiota and metabolites in healthy rats and CIA rats. In this study, high humidity aggravated arthritis in CIA rats, including articular cartilage lesions, arthritis scores, and proinflammatory cytokines. High humidity had a certain effect on articular cartilage extent, arthritis score and proinflammatory cytokines of healthy rats. Furthermore, high humidity caused significant changes in faecal microbes and faecal metabolites in healthy and CIA rats. Sequencing of the 16S rRNA unit in faecal samples showed that high humidity aggravated inflammation-related bacteria in healthy and CIA rats. Faecal metabolomics results showed that high humidity significantly altered faecal metabolites in healthy rats and CIA rats, and the changes in biological functions were mainly related to the inflammatory response and oxidative stress. Combined analysis showed that there was a strong correlation between the faecal microbiota and faecal metabolites. High humidity is an adverse factor for the onset and development of RA, and its mechanism is related to the inflammatory response and oxidative stress. However, how high humidity leads to the pathogenesis of RA needs to be further determined.
Optimal use of serum leucine-rich alpha-2 glycoprotein as a biomarker for small bowel lesions of Crohn's disease
Authors: Asonuma Kunio , Kobayashi Taku , Kikkawa Nao , Nakano Masaru , Sagami Shintaro , Morikubo Hiromu , Miyatani Yusuke , Hojo Aya , Fukuda Tomohiro , Hibi Toshifumi 
Published: August 2022

Abstract
A large proportion of small bowel lesions in Crohn’s disease (CD) may exist beyond the scope of ileocolonoscopy, suggesting the need for optimal biomarkers. This cross-sectional observational study prospectively measured C-reactive protein (CRP), faecal calprotectin (FC), and leucine-rich alpha-2 glycoprotein (LRG) in patients with quiescent CD who underwent imaging examinations (capsule or balloon-assisted endoscopy, magnetic resonance enterography, or intestinal ultrasound). Mucosal healing (MH) of the small bowel was defined as a lack of ulcers. Patients with a Crohn’s disease activity index of >220 and active colonic lesions were excluded. Seventy patients (29, MH; 41, small bowel inflammation) were analysed. The area under the curve (AUC) of CRP, FC, and LRG was 0.74 (95% confidence interval 0.60-0.86), 0.68 (0.52-0.80), and 0.75 (0.58-0.84), respectively. A cut-off of 16 μg/ml of LRG showed the highest positive predictive value of 0.95 with a specificity of 0.96, while the negative predictive value was the highest (0.71) with a sensitivity of 0.90 at a cut-off of 9 μg/ml. This suggests that LRG can accurately detect and/or exclude the small bowel lesions using two cut-off values.
Evaluation of periodic stability of the oral microbiome from a healthy cohort using 16S ribosomal RNA gene sequencing analysis
Authors: Mangal Utkarsh , Noh Kowoon , Lee Seeyoon , Cha Jae-Kook , Song Je Seon , Cha Jung-Yul , Lee Kee-Joon , Kim Kwang-Mahn , Kwon Jae-Sung , Choi Sung-Hwan 
Published: August 2022

Abstract
ObjectivesThe use of 16S ribosomal RNA gene sequencing analyses has rapidly increased in clinical oral studies. However, cohort-based clinical research has not sufficiently accounted for the periodic stability in oral microbiota. Herein, we aimed to assess the stability of the oral microbiome across time from an intervention-free “healthy” cohort. Materials and MethodsWe obtained 33 supragingival samples of 11 healthy participants from the biobank. For each participant, we processed one sample as baseline (T0) and two samples spaced at monthly (T1) and quarterly (T2) intervals for 16S ribosomal RNA gene sequencing analysis. ResultsWe observed that taxonomic profiling had a similar pattern of dominant genera, namely Rothia, Prevotella, and Hemophilus, at all-time points. Shannon diversity revealed a significant increase from T0 (p<0.05). Bray Curtis dissimilarity was significant (R=-0.02, p<0.01) within the cohort at each time point. Clustering revealed marked differences in the grouping patterns between the three-time points. For all time points, the clusters presented a substantially dissimilar set of differentially abundant taxonomic and functional biomarkers. ConclusionOur observations confirmed presence of periodically different stable states within the oral microbiome in an intervention-free healthy cohort. Accounting for multi-stability will improve the understanding of future research and facilitate identifying and classifying the reliable markers of diseased, healing, healed, and healthy states.Clinical relevanceThe high periodic variation within a healthy cohort demonstrated the presence of multiple stable states within an individual. Clinical research using RNA gene sequencing for comparison should adopt microbiome specific selection criteria for careful classification of a health-associated group.
Small grains from Ryugu: handling and analysis pipeline for Infrared Synchrotron Microspectroscopy
Authors: Rubino Stefano , Dionnet Zélia , Aléon-Toppani Alice , Brunetto Rosario , Nakamura Tomoki , Baklouti Donia , Djouadi Zahia , Lantz Cateline , Mivumbi Obadias , Borondics Ferenc , Lefrançois Stephane , Sandt Christophe , Capitani Francesco , Héripré Eva , Troadec David , Matsumoto Megumi , Amano Kana , Morita Tomoyo , Yurimoto Hisayoshi , Noguchi Takaaki , Okazaki Ryuji , Yabuta Hikaru , Naraoka Hiroshi , Sakamoto Kanako , Tachibana Shogo , Watanabe Seiichiro , Tsuda Yuichi 
Published: August 2022

Abstract
Sample-return missions allow the study of materials collected directly from celestial bodies, unbiased by atmospheric entry effects and/or terrestrial alteration and contamination phenomena, using state-of-the-art techniques which are available only in a laboratory environment - but only if the collected material stays pristine. The scarcity of outer-space unaltered material recovered until now makes this material extremely precious for the potential scientific insight it can bring. To maximize the scientific output of current and future sample-return missions, the scientific community needs to plan for ways of storing, handling, and measuring this precious material while preserving their pristine state for as long as the ‘invasiveness’ of measurements allows. In July 2021, as part of the Hayabusa2 (JAXA) “Stone” preliminary examination team, we received several microscopic particles from the asteroid Ryugu, with the goal of performing IR hyper-spectral imaging and IR micro-tomography studies. Here we describe the sample transfer, handling methods and analytical pipeline we implemented to study this very precious material while minimizing and surveilling their alteration history on Earth.
A parametric approach to estimate streamflow quantiles using annual flow–duration curves
Authors: Asikoglu Omer Levend , Narin Tugce 
Published: August 2022

Abstract

The flow–duration curve (FDC) is a significant instrument used in solving many hydrological and environmental problems such as evaluating water quality, examining water supply and use for hydroelectric generation and irrigation, and investigating sedimentation and low flows. However, the insufficiency of flow data allows FDCs to be used only for gauged basins or gauged locations in a basin. Therefore, obtaining regional relationships that provide effective estimates about a region, by using the records of existing stations in the region, becomes necessary. This paper illustrates a simple parametric approach, where droughts are characterized by using the lower part of the annual flow–duration curve. The paper uses the actual instantaneous flow data of 30 basins in Western Anatolia and 21 basins in Southwestern Anatolia, Turkey to offer a new perspective for the estimation of streamflow quantiles using Areal Scale Factors (ASFs), which efficiently represent the relationship between flow quantile and basin area.
Comparison of purse-string suture versus over-the-scope clip for gastric endoscopic full-thickness closure: traction and leak pressure testing in ex vivo porcine model
Authors: Matsui Takanori , Kobara Hideki , Nishiyama Noriko , Nakatani Kaho , Shi Tingting , Tada Naoya , Kozuka Kazuhiro , Kobayashi Nobuya , Chiyo Taiga , Yachida Tatsuo , Kondo Akihiro , Kishino Takayoshi , Okano Keiichi , Fujihara Shintaro , Uchita Kunihisa , Hirasawa Kingo , Masaki Tsutomu 
Published: August 2022

Abstract
Background The recently developed endoscopic full-thickness resection technique requires reliable closure. The main closure methods are the purse-string suture (PSS) technique and over-the-scope clip (OTSC) technique; however, basic data on the suture strength of each technique are lacking. This study was performed to compare the suture strengths of these two methods in an ex vivo porcine model. Methods In the traction test, a virtual 5-cm full-thickness suture line was closed by the following six methods three times each: conventional hemoclips, mucosal PSS, seromuscular PSS, mucosal OTSC, seromuscular OTSC, and surgical suture. The primary endpoint was the tension at the starting point of dehiscence, measured in Newtons (N) by an automatic traction machine. In the leak test, a 15-mm gastric full-thickness defect was closed by PSS or OTSC six times each, and the sutured stomach was then pressurized in a water container. The primary endpoint was the leak pressure when air bubbles appeared. The secondary endpoints were the procedure time and presence of complete inverted closure.Results The mean tension was 2.16, 3.68, 5.15, 18.30, 19.30, and 62.40 N for conventional hemoclips, mucosal PSS, seromuscular PSS, mucosal OTSC, seromuscular OTSC, and surgical suture, respectively. Complete inverted closure was observed for seromuscular PSS, seromuscular OTSC, and surgical suture. The mean leak pressure was 13.7 and 24.8 mmHg in the PSS and OTSC group, respectively (P < 0.01). The mean procedure time was 541 and 169 seconds in the PSS and OTSC group, respectively (P < 0.01). Complete inverted closure was observed in OTSC alone.Conclusion The OTSC, which allows complete inverted closure, showed greater suture strength than PSS.
Dysphagia lusoria in a young patient with a concomitant aortic arch anomaly, successfully treated with surgery. A case report.
Authors: Endara Santiago A. , Davalos Gerardo A , Cardenas Alberto , Gangotena Karina , Flores Alexis , Molina Gabriel Alejandro 
Published: August 2022

Abstract
BackgroundDysphagia is a relatively common problem in clinical practice, however, an unusual type of dysphagia due to compression of the esophagus by an abnormal right subclavian artery may be discovered in a rare subset of patients. The prognosis and treatment will depend on the severity of the symptoms and the compromise of surrounding structures.Case PresentationWe present the case of an 18-year-old female without past medical history. She suffered a two-month gradually progressive dysphagia accompanied by mild reflux. At first, it was treated as gastroesophageal reflux disease, without result. Dysphagia became severe and additional exams were required. An aberrant right subclavian artery that compressed the esophagus was discovered along with a truncus bicaroticus. She was successfully treated with surgery without any complications. On follow-ups, she's doing well.ConclusionsA symptomatic aberrant right subclavian artery, although rare, should always be corrected after diagnosis to solve symptoms and prevent possible complications. In addition, when necessary, reconstruction of the blood flow to the upper extremity to maintain the arm’s viability and keep the spinal and vertebrobasilar circulation is of paramount importance.