bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effects of wearing a face mask and of subsequent moisturizer use on the characteristics of sensitive skin
Authors: Yoo Mi Ae , Kim Song Hee , Han Hyo Sun , Byun Ji Won , Park Keun Hyung 
Published: May 2022

AbstractBackgroundCOVID‐19 is a serious respiratory disease, and wearing masks has become essential in daily life. Nevertheless, the number of people complaining of skin problems caused by wearing masks is increasing. Therefore, we investigated the characteristics of changes in sensitive skin caused by wearing a mask.Materials and methodsTwenty healthy Korean women with sensitive skin participated in this study. To determine any skin‐related changes caused by mask‐wearing, we evaluated redness, hydration, transepidermal water loss (TEWL), and moisture at 2.5 mm below the surface before and 4 h after wearing a Korea Filter 94 mask. In addition, we tested whether applying a moisturizer for 30 min after mask removal could reverse any mask‐induced changes.ResultsSkin redness and TEWL were significantly increased at 4 h after wearing a mask (p < 0.05), otherwise skin hydration and the 2.5 mm moisture were significantly decreased (p < 0.05). After applying the moisturizer, skin redness and TEWL were significantly decreased compared to their values 4 h after wearing masks (p < 0.05), whereas skin hydration and the 2.5 mm moisture were significantly increased (p < 0.05). Moreover, after applying the moisturizer, skin redness and TEWL were significantly reduced compared to the pre‐masking baseline (p < 0.05), whereas skin hydration was significantly increased (p < 0.05); the 2.5 mm moisture showed no significant change.ConclusionWe observed that wearing masks causes physiological changes in sensitive skin, whereas applying a moisturizer after removing the mask improved skin conditions.
Investigating quality of life instrument measurement properties for adults with active venous leg ulcers: A systematic review
Authors: Liu Shiwen , Team Victoria , Qiu Yunjing , Weller Carolina D. 
Published: May 2022

AbstractThe primary objective of this systematic review was to identify which quality of life instruments have been applied in published studies of patients with active venous leg ulcers. Our secondary objective was to map the measurement properties of each identified quality of life instrument and to inform future recommendations for clinical practice and research. We searched CINAHL, Ovid Medline, Ovid Emcare and ProQuest to identify studies published from 1 January 2000 to 31 July 2021. Eleven studies that utilised quality of life instruments in adults with active venous leg ulcers met the inclusion criteria. Thirteen quality of life instruments were identified as some studies utilised both generic and condition‐specific quality of life instruments. Six out of nine (6/9) instruments were rated ‘very good’ of methodological quality on internal consistency; 1/7 studies rated ‘adequate’ on reliability; 2/4 rated ‘adequate’ on content validity; 3/6 studies rated ‘adequate’ on structural validity; 5/6 rated ‘adequate’ on hypotheses testing for construct and 2/6 studies rated ‘adequate’ on responsiveness. There is limited evidence of measurement properties of quality of life instruments for people with active venous leg ulcers. The Venous Leg Ulcer Quality of Life Questionnaire (VLU‐QoL) could be provisionally recommended for use although from our review it is clear further studies to assess VLU‐QoL measurement properties are needed to inform future recommendations for clinical practice and research.
Epidural electrical stimulation of the cervical spinal cord opposes opioid‐induced respiratory depression
Authors: Huang Ruyi , Worrell Jason , Garner Eric , Wang Stephanie , Homsey Tali , Xu Bo , Galer Erika L. , Zhou Yan , Tavakol Sherwin , Daneshvar Meelod , Le Timothy , Vinters Harry V. , Salamon Noriko , McArthur David L. , Nuwer Marc R. , Wu Irene , Leiter James C. , Lu Daniel C. 
Published: May 2022

AbstractOpioid overdose suppresses brainstem respiratory circuits, causes apnoea and may result in death. Epidural electrical stimulation (EES) at the cervical spinal cord facilitated motor activity in rodents and humans, and we hypothesized that EES of the cervical spinal cord could antagonize opioid‐induced respiratory depression in humans. Eighteen patients requiring surgical access to the dorsal surface of the spinal cord between C2 and C7 received EES or sham stimulation for up to 90 s at 5 or 30 Hz during complete (OFF‐State) or partial suppression (ON‐State) of respiration induced by remifentanil. During the ON‐State, 30 Hz EES at C4 and 5 Hz EES at C3/4 increased tidal volume and decreased the end‐tidal carbon dioxide level compared to pre‐stimulation control levels. EES of 5 Hz at C5 and C7 increased respiratory frequency compared to pre‐stimulation control levels. In the OFF‐State, 30 Hz cervical EES at C3/4 terminated apnoea and induced rhythmic breathing. In cadaveric tissue obtained from a brain bank, more neurons expressed both the neurokinin 1 receptor (NK1R) and somatostatin (SST) in the cervical spinal levels responsive to EES (C3/4, C6 and C7) compared to a region non‐responsive to EES (C2). Thus, the capacity of cervical EES to oppose opioid depression of respiration may be mediated by NK1R+/SST+ neurons in the dorsal cervical spinal cord. This study provides proof of principle that cervical EES may provide a novel therapeutic approach to augment respiratory activity when the neural function of the central respiratory circuits is compromised by opioids or other pathological conditions.Key points
Epidural electrical stimulation (EES) using an implanted spinal cord stimulator (SCS) is an FDA‐approved method to manage chronic pain.
We tested the hypothesis that cervical EES facilitates respiration during administration of opioids in 18 human subjects who were treated with low‐dose remifentanil that suppressed respiration (ON‐State) or high‐dose remifentanil that completely inhibited breathing (OFF‐State) during the course of cervical surgery.
Dorsal cervical EES of the spinal cord augmented the respiratory tidal volume or increased the respiratory frequency, and the response to EES varied as a function of the stimulation frequency (5 or 30 Hz) and the cervical level stimulated (C2–C7).
Short, continuous cervical EES restored a cyclic breathing pattern (eupnoea) in the OFF‐State, suggesting that cervical EES reversed the opioid‐induced respiratory depression.
These findings add to our understanding of respiratory pattern modulation and suggest a novel mechanism to oppose the respiratory depression caused by opioids.
Effectiveness of weight management interventions for adults delivered in primary care: systematic review and meta-analysis of randomised controlled trials
Authors: Madigan Claire D , Graham Henrietta E , Sturgiss Elizabeth , Kettle Victoria E , Gokal Kajal , Biddle Greg , Taylor Gemma M J , Daley Amanda J 
Published: May 2022

AbstractObjectiveTo examine the effectiveness of behavioural weight management interventions for adults with obesity delivered in primary care.DesignSystematic review and meta-analysis of randomised controlled trials.Eligibility criteria for selection of studiesRandomised controlled trials of behavioural weight management interventions for adults with a body mass index ≥25 delivered in primary care compared with no treatment, attention control, or minimal intervention and weight change at ≥12 months follow-up.Data sourcesTrials from a previous systematic review were extracted and the search completed using the Cochrane Central Register of Controlled Trials, Medline, PubMed, and PsychINFO from 1 January 2018 to 19 August 2021.Data extraction and synthesisTwo reviewers independently identified eligible studies, extracted data, and assessed risk of bias using the Cochrane risk of bias tool. Meta-analyses were conducted with random effects models, and a pooled mean difference for both weight (kg) and waist circumference (cm) were calculated.Main outcome measuresPrimary outcome was weight change from baseline to 12 months. Secondary outcome was weight change from baseline to ≥24 months. Change in waist circumference was assessed at 12 months.Results34 trials were included: 14 were additional, from a previous review. 27 trials (n=8000) were included in the primary outcome of weight change at 12 month follow-up. The mean difference between the intervention and comparator groups at 12 months was −2.3 kg (95% confidence interval −3.0 to −1.6 kg, I2=88%, P<0.001), favouring the intervention group. At ≥24 months (13 trials, n=5011) the mean difference in weight change was −1.8 kg (−2.8 to −0.8 kg, I2=88%, P<0.001) favouring the intervention. The mean difference in waist circumference (18 trials, n=5288) was −2.5 cm (−3.2 to −1.8 cm, I2=69%, P<0.001) in favour of the intervention at 12 months.ConclusionsBehavioural weight management interventions for adults with obesity delivered in primary care are effective for weight loss and could be offered to members of the public.Systematic review registrationPROSPERO CRD42021275529.
Randomised controlled trial of a behaviour change physiotherapy intervention to increase physical activity following hip and knee replacement: the PEP-TALK trial
Authors: Smith Toby O , Parsons Scott , Ooms Alexander , Dutton Susan , Fordham Beth , Garrett Angela , Hing Caroline , Lamb Sarah 
Published: May 2022

ObjectiveTo test the effectiveness of a behaviour change physiotherapy intervention to increase physical activity compared with usual rehabilitation after total hip replacement (THR) or total knee replacement (TKR).DesignMulticentre, pragmatic, two-arm, open, randomised controlled, superiority trial.SettingNational Health Service providers in nine English hospitals.Participants224 individuals aged ≥18 years, undergoing a primary THR or TKR deemed ‘moderately inactive’ or ‘inactive’.InterventionParticipants received either six, 30 min, weekly, group-based exercise sessions (usual care) or the same six weekly, group-based, exercise sessions each preceded by a 30 min cognitive behaviour discussion group aimed at challenging barriers to physical inactivity following surgery (experimental).Randomisation and blindingInitial 75 participants were randomised 1:1 before changing the allocation ratio to 2:1 (experimental:usual care). Allocation was based on minimisation, stratifying on comorbidities, operation type and hospital. There was no blinding.Main outcome measuresPrimary: University of California Los Angeles (UCLA) Activity Score at 12 months. Secondary: 6 and 12-month assessed function, pain, self-efficacy, kinesiophobia, psychological distress and quality of life.ResultsOf the 1254 participants assessed for eligibility, 224 were included (139 experimental: 85 usual care). Mean age was 68.4 years (SD: 8.7), 63% were women, 52% underwent TKR. There was no between-group difference in UCLA score (mean difference: −0.03 (95% CI −0.52 to 0.45, p=0.89)). There were no differences observed in any of the secondary outcomes at 6 or 12 months. There were no important adverse events in either group. The COVID-19 pandemic contributed to the reduced intended sample size (target 260) and reduced intervention compliance.ConclusionsThere is no evidence to suggest attending usual care physiotherapy sessions plus a group-based behaviour change intervention differs to attending usual care physiotherapy alone. As the trial could not reach its intended sample size, nor a proportion of participants receive their intended rehabilitation, this should be interpreted with caution.Trial registration numberISRCTN29770908.
Clinical profile and outcome of recurrent infective endocarditis
Authors: Citro Rodolfo , Chan Kwan-Leung , Miglioranza Marcelo Haertel , Laroche Cécile , Benvenga Rossella Maria , Furnaz Shumaila , Magne Julien , Olmos Carmen , Paelinck Bernard P. , Pasquet Agnès , Piper Cornelia , Salsano Antonio , Savouré Arnaud , Park Seung Woo , Szymański Piotr , Tattevin Pierre , Vallejo Camazon Nuria , Lancellotti Patrizio , Habib Gilbert 
Published: May 2022

AimsPurpose of this study is to compare the clinical course and outcome of patients with recurrent versus first-episode infective endocarditis (IE).MethodsPatients with recurrent and first-episode IE enrolled in the EUROpean ENDOcarditis (EURO-ENDO) registry including 156 centres were identified and compared using propensity score matching. Recurrent IE was classified as relapse when IE occurred ≤6 months after a previous episode or reinfection when IE occurred >6 months after the prior episode.Results3106 patients were enrolled: 2839 (91.4%) patients with first-episode IE (mean age 59.4 (±18.1); 68.3% male) and 267 (8.6%) patients with recurrent IE (mean age 58.1 (±17.7); 74.9% male). Among patients with recurrent IE, 13.2% were intravenous drug users (IVDUs), 66.4% had a repaired or replaced valve with the tricuspid valve being more frequently involved compared with patients with first-episode IE (20.3% vs 14.1%; p=0.012). In patients with a first episode of IE, the aortic valve was more frequently involved (45.6% vs 39.5%; p=0.061). Recurrent relapse and reinfection were 20.6% and 79.4%, respectively.Staphylococcus aureuswas the microorganism most frequently observed in both groups (p=0.207). There were no differences in in-hospital and post-hospitalisation mortality between recurrent and first-episode IE. In patients with recurrent IE, in-hospital mortality was higher in IVDU patients. Independent predictors of poorer in-hospital and 1-year outcome, including the occurrence of cardiogenic and septic shock, valvular disease severity and failure to undertake surgery when indicated, were similar for recurrent and first-episode IE.ConclusionsIn-hospital and 1-year mortality was similar in patients with recurrent and first-episode IE who shared similar predictors of poor outcome.
Reliability of three-dimensional motion analysis during single-leg side drop landing test after anterior cruciate ligament reconstruction: An in vivo motion analysis study
Authors: Pang Johnson Chun Yiu , Tsang Rachel Suet Wai 
Published: May 2022

Background: Anterior cruciate ligament (ACL) injury is a common sport injury and investigation of landing biomechanics is helpful in injury prevention and rehabilitation. Recent study found a lateral single-leg drop landing test resulted in the highest peak knee valgus angle (PKVA), but its reliability on patients who received ACL reconstruction (ACLR) is unknown. Objective: This study aimed to investigate the reliability in both within and between days on the normalized vertical ground reaction force (NVGRF) and kinematics of lower limbs after receiving ACLR. The findings can form the cornerstone for further study related to lateral jumping-and-landing biomechanics in patients with ACLR. Methods: This was a test-retest reliability study. Twelve patients (four females and eight males) who received ACLR with mean age of 29.4 (SD [Formula: see text] 1.66) were recruited. The subjects were instructed to jump laterally from 30[Formula: see text]cm height and landed with single-leg for five times. The procedure was conducted on both legs for comparison. The NVGRF and local maxima of the hip, knee and ankle angles during the first 100[Formula: see text]ms in all three planes were analyzed. The measurement was conducted by the same assessor to evaluate the within-session reliability, and the whole procedure was repeated one week later for the evaluation of the between-session reliability. Intra-class correlation coefficient (ICC) test was used to assess the within- and between-session reliability by ICC (3, 1) and ICC (3, K) respectively. Results: The within-session reliability of NVGRF [ICC (3, 1)] was 0.899–0.936, and its between-session reliability [ICC (3, K)] was 0.947–0.923. Overall reliability for kinematics within-session [ICC (3, 1)] was 0.948–0.988, and the between-session reliability [ICC (3, K)] was 0.618–0.982, respectively. Good to excellent reliability for the lateral single-leg drop landing test was observed in most of the outcome measures for within- and between-session. The ICC value of NVGRF of ACLR leg was lower than that of the good leg in the within-session which may associate with lower neuromuscular control in ACLR leg than that of the good leg. Conclusion: The results of this study support the use of a lateral single-leg drop landing test to evaluate lower limb biomechanics for ACLR.
A tracking control design for linear motor using robust sliding mode learning control
Authors: Al-nasrawi Mukhalad , Al_Ghanimi Ali , Mashkor Alaa Abdalhussain Aldahlemi 
Published: May 2022

<div id="i4c-draggable-container" style="position: fixed; z-index: 1499; width: 0px; height: 0px;"><div class="resolved" style="all: initial;" data-reactroot=""> </div></div><p>In this paper, a tracking robust sliding mode learning control (SMLC) is proposed for a linear motor (LM) system. The proposed controller approach, SMLC, can guarantee a zero tracking error in the absence and presence of system uncertainties of the LM system. Unlike other classical sliding mode control (CSMC), the proposed control system is designed without any prior knowledge of the system perturbation which would facilitate control design and simplify its practical applications. To this end, a recursive learning technique is used which simultaneously adapted based on the previous information of the closed loop system stability. The system stability and convergence analysis are rigorously proved in the sense of the Lybenouve criteria. Finally, simulations results are presented to demonstrate the validity and effectiveness of the SMLC over the CSMC in terms of tracking performance and chattering alleviation.</p>
Accused of infanticide
Authors: Monballyu J. 
Published: May 2022

Summary
In Belgium, from 1796 until 1867, infanticide was a crime which was legally defined as the deliberate homicide of a new-born child and punished with the death penalty. In the province of West Flanders, for a long time the second most populous province in Belgium, this crime was strongly women-related. As in the other Belgian provinces and abroad, this crime was mainly committed by unmarried domestic servants who lived with their employer and with whom there was no time nor a place for a mother with a child. Infanticide was a crime that was prosecuted before the Court of Assizes of West Flanders and its predecessors. Such prosecutions happened rather exceptionally (109 people in all were prosecuted in West Flanders over a period of 70 years, i.e. an average of 1.5 per year), albeit in a steadily increasing line and with a peak during the years 1850-1867. The Court of Assizes punished this crime only very exceptionally with the statutory death penalty (only in 34 cases, i.e. 31% of the 109 accused). The other 75 accused were either acquitted (58 cases, i.e. 53% of the accused) or punished for another offence (17 cases, i.e. 15.5% of the accused). The acquittals and the punishments for another offence were not the result of the jurors’ or professional judges’ inclination to accept the puerperal insanity of the accused women, but a consequence of the fact that it was exceedingly difficult to prove that a child had been born viable, had lived independently of the mother for a while, and had been killed with the clear intention of killing it, when the child’s mother had given birth without assistance and claimed that the child had been still-born or died from a natural cause.
Creditor fructus percepit, Sul pegno con patto anticretico
Authors: Perani R. 
Published: May 2022

Summary
Creditor fructus percepit, On pledge with a pactum antichreticum. – May the pledgee take the benefits of the res? Pledge did not allow it, there would have been theft (furtum usus). In fact, the thing given as pledge was excluded from any economic use. However, Roman law attests an agreement called ἀντίχρησις, which allowed the creditor to have the fruits of the res, under some conditions. Among the jurists only Marcianus uses this Greek term (in D.13,7,33 and D.20,1,11,1).
In this paper, I wish to demonstrate that the antichresis has become part of Roman legal thought. The legal sources attest a late appearance of the antichresis (very late 2nd and early 3rd century AD), but some Severian constitutions suggest that it may already have been known in practice. The Greek word indicated its foreign origin, but Roman jurists called it simply pignus.
Modulation of physiological responses and tolerance of Alternanthera tenella Colla (Amaranthaceae) to cadmium during in vitro cultivation
Authors: Clairvil Evens , Martins João Paulo Rodrigues , Braga Priscila da Conceição de Souza , Cipriano Rosiane , Conde Lorenzo Toscano , Moreira Samuel Werner , Rossini Franciele Pereira , Falqueto Antelmo Ralph , Gontijo Andreia Barcelos Passos Lima 
Published: May 2022

Abstract
The use of plants that present clear physiological responses to heavy metals such as cadmium (Cd) can assist in environmental monitoring. The aim was to evaluate physiological responses of Cd in Alternanthera tenella plants in micro-controlled conditions and to assess the its tolerance level and bioindicator potential. Nodal segments of A. tenella were grown in flasks containing semi-solid MS medium supplemented with (0, 50, 100, and 150 μM Cd). The total fresh and dry weight of the plants, in addition to physiological analyses, were determined after 30 days of cultivation. Plants submitted to Cd showed a reduction in biomass and photosynthetic pigments content. The decline in the Chl a/b ratio indicated the deleterious effects of Cd, as evidenced by the decrease in the density of active reaction centers (RC/CSM). The levels of deterioration in the functionality or structural integrity of the thylakoid membranes (WL) and the activity of the oxygen evolution complex (WK) increased as a function of Cd concentrations. The decreases in photochemical and non-photochemical quenching (qP and qN, respectively) observed in plants exposed to Cd indicated photochemical dysfunctions. Additionally, the increase in the quantum yield of non-regulated energy dissipation (ΦNO) indicated the presence of photodamage. Plants had a low/intermediate TI level (≥21.7) in the analyzed concentration range. A. tenella plants can bioaccumulate high amounts of Cd. The level of physiological responses of A. tenella is dependent on the concentration of Cd, which makes the use of this species even more promising as a bioindicator for this metal.
Development of a Climate Change SSIBL-STEAM Program Aligned to the National Curriculum for SSI Elementary School in Korea
Authors: Baek Seongheui , Shin Hyeonjeong , Kim Chan-Jong 
Published: May 2022

Abstract
This study describes the development of a climate change SSIBL-STEAM program that was aligned to the Grade 6 elementary school national curriculum using the ADDIE model for design. The efficacy of the climate change SSIBL-STEAM program was investigated by measuring the impact of the program on cultivating elementary students’ personalities (sociality, morality, emotion) and STEAM (Science, Technology, Engineering, Arts, Mathematics) competencies (convergence, creativity, challenge, caring). Twenty-five Grade 6 students and three public elementary school teachers participated in this study. Data were collected using two instruments designed to examine character and STEAM competencies before and after the program. Additionally, field notes and student learning outcomes were collected and qualitatively and quantitively analyzed. The results indicated that students improved significantly in their character and STEAM competencies, especially morality, emotion, and convergence factors. This study was expected to be an example of the combined approach with SSIBL and STEAM.