bluuebunny/crossref_metadata_2025_split huggingface dataset:
Export Expansion May Increase Adult Illness and Injury: A Quasi-Natural Experiment on China's Accession to the World Trade Organization
Authors: Chen Hongwen , Xu Junbing , Liu Jianzheng 
Published: April 2022

PurposeExports can boost the economy, but may also cause harm to health through, for example, increased pollution and working hours. Although academic research extensively covers the impact of trade on health, few studies examine the mechanisms through which export expansion affects adult illness or injury within the past 4 weeks (illness/injury).MethodWe utilized China's entry into the World Trade Organization (WTO) as a quasi-natural experiment to investigate the relationship between export expansion and adult illness/injury. We explored the possible mechanisms and the heterogeneity of these associations. Our methodology was based on the analysis of China's Health and Nutrition Survey data, Chinese Customs databases, and China's Statistical Yearbook.ResultsExport expansion, induced by China's accession to the WTO, has a significantly positive effect on adult illness/injury [average effect (AE): 1.83%; 95% CI: 0.38–3.28%]. Our results remain robust following a series of robustness tests. Moreover, the effects of export expansion on adult illness/injury are more pronounced among urban residents (AE: 5.32%; 95% CI: 2.46–8.18%), women (AE: 2.68%; 95% CI: 0.57–4.80%), and higher-income groups (AE: 5.90%; 95% CI: 2.53–9.27%).ConclusionsWe find a statistically significant and positive effect of export expansion on adult illness/injury.
Health-Related Quality of Life and Its Related Factors in Survivors of Stroke in Rural China: A Large-Scale Cross-Sectional Study
Authors: Mei Yong-xia , Zhang Zhen-xiang , Wu Hui , Hou Jian , Liu Xiao-tian , Sang Sheng-xiang , Mao Zhen-xing , Zhang Wei-hong , Yang Dong-bin , Wang Chong-jian 
Published: April 2022

BackgroundStroke is a major health threat and the leading cause of mortality and disability in China. The aims of this study were to identify the possible influencing factors of health-related quality of life (HRQoL) and its domain-specific contents in stroke patients in rural areas in China.MethodsA total of 1,709 stroke patients aged 36–79 years from the baseline data of Henan Rural Cohort study (n = 39,259) were included in the cross-sectional study. The Chinese version of the European Quality of Life Five Dimension (including mobility, self-care, usual activities, pain/discomfort, and anxiety/depression) Five Level Scale (EQ-5D-5L) and visual analog scale (VAS) were used to evaluate HRQoL in stroke patients. Tobit regression models, generalized linear models and binary logistic regression models were constructed to determine potential influencing factors of the EQ-5D utility index, as well as influencing factors of each domain and VAS score.ResultsThe mean utility index and VAS scores of stroke patients were 0.885 (SD, 0.204), and 68.39 (SD, 17.31), respectively. Pain/discomfort (PD, 35.2%) and mobility (MO, 30.4%) were the most frequently reported issues. Regression models revealed that illiterate; a low monthly income; low physical activity intensity; and diabetes, anxiety, depression, or poor sleep quality were significantly associated with lower utility index and VAS scores among stroke patients. In addition, patients with stroke who were older, female, drinking, smoking, and consuming a high-fat diet, had a higher BMI, and lived with a stroke for a longer time, were also significantly associated with different dimensions of the EQ-5D.ConclusionPatients with stroke in rural areas in China had a low HRQoL. Factors associated with the EQ-5D utility index as well as each domain and VAS score, need to be considered by health providers in rural areas. Patients with stroke in rural areas need to be included in national basic public medical services and managed systematically by medical institutions.
Price Policy and Taxation as Effective Strategies for Tobacco Control
Authors: Felsinger Richard , Groman Ernest 
Published: April 2022

ObjectiveOnly 13% of the world's population are living in countries imposing appropriate tobacco tax-rates. This study aims to promote the implementation of price policy measures as a striking tobacco control strategy in Austria and to encourage other countries to further increase their taxes to WHO best-practice levels.MethodThis study used the yearly economic data from Austria from 1997 to 2015. Applying a model for regression analysis, the price elasticity of total tobacco consumption was estimated.ResultsBetween 1997 and 2015 the price elasticity of demand for tobacco products (including cigarettes, cigars, and other tobaccos) was −0.661, however, the result is statistically insignificant. When excluding 2 anomalous years and removing a variable of the regression model the elasticity was −0.691 and statistically significant, indicating that a 1% increase in tobacco prices will result in a 0.691% decrease of tobacco consumption.ConclusionThe responsiveness of Austrian smokers to price changes has increased during the last decades. Because other activities showed no significance in the analysis, this study should encourage countries world-wide to use price policy and taxation more intensively in order to reduce smoking rates effectively.
The COVID-19 Pandemic Related Lived Experiences of Individuals With a Spinal Cord Injury/Disease
Authors: Simpson Ethan , Miller William C. , Schmidt Julia , Borisoff Jaimie , Mortenson W. Ben 
Published: April 2022

IntroductionCOVID-19 related restrictions and recommendations have impacted everyone. Those living with a disability, such as individuals with a spinal cord injury (SCI), may have had pandemic related changes made yet more challenging by societal failures to accommodate their mobility, physical abilities, and health care needs. To better understand participants experiences we drew upon Heidegger's phenomenology and the mobilities paradigm. The objective of this study was to explore COVID-19 pandemic related lived-experiences of individuals with an SCI.Materials and MethodsThis study used an interpretive phenomenological methodology. Semi-structured interviews were the primary means of data collection. These were conducting in May and June of 2020, roughly 2–3 months into the pandemic. Transcript data were analyzed using a phenomenological methodology.ResultsWe interviewed 22 participants with SCI, the mean age was 54 years, and nine were females. We identified three themes: (1) Experiencing changes to mobility and daily life described how new rules had impacted everyday life and usual routines, particularly in regard to mobility. (2) Struggling with new challenges explored some of the negative experiences of the pandemic. (3) Being resilient in the face of a new normal conveyed the resilience participants exhibited despite challenges.ConclusionAlthough our findings indicate some positive changes and highlight the strengths that many individuals with SCI have, they also accentuate issues with ableism within the medical system. Certain changes were made primarily because people without disabilities needed them, and several COVID-19 changes were made without consulting individuals with disabilities. With physical movement restricted, our findings emphasize the importance of the movement of information and a need for increased dialogue with people in the SCI community about their ongoing pandemic related needs.
RETRACTED: Safety Evaluation of Antituberculosis Drugs During Pregnancy: A Systematic Review and Meta-Analysis
Authors: Zhou Xiaomei , Fang Guoying , Xie Yaqing , Wei Anqi , Huang Feixiang 
Published: April 2022

BackgroundPregnant women are a common group of people with tuberculosis,especially in patients infected with HIV at the same time. Antituberculosis drug prophylaxis is effective in reducing tuberculosis infection in pregnant women and fetuses after pregnancy, but its safety is still worthy of in-depth discussion. In this study, we conducted a systematic review and meta-analysis of reports on the use of antituberculosis drugs during pregnancy in recent years to provide evidence for clinical diagnosis and treatment.MethodsThe PubMed, Embase, Web of Science databases, Ovid, and clinicaltrials.gov were searched. Search for clinical randomized controlled studies and cohort studies on the use of antituberculosis drugs during pregnancy published in the databases from January 2000 to September 2021 was performed using the Stata 16.0 software after screening qualified bodies of literature.ResultsOn the basis of the initial search of 408 articles, this study included a total of 8 articles and 2,563 patients after screening; meta-analysis results showed that preventive treatment with antituberculosis drugs did not increase the incidence of serious maternal adverse events [RR = 0.99, 95% CI (.88, 1.12), Z = −0.108, P = 0.914], did not increase drug hepatotoxicity [RR = 1.13, 95% CI (.9, 1.43), Z = 1.071, P = 0.284], did not increase the incidence of peripheral nerve disease [RR = 1.52, 95% CI (.85, 2.71), Z = 1.412, P = 0.158], did not increase maternal mortality [RR = 0.67, 95% CI (.27, 1.7), Z = −0.84, P = 0.401], and could significantly reduce adverse pregnancy outcomes [RR = 0.78, 95% CI (0.68, 0.89), Z = −3.581, P &lt; 0.0001].DiscussionThe use of antituberculosis drugs for preventive treatment during pregnancy is safe and can obtain better pregnancy outcomes.
Co-Detection of VEGF-A and Its Regulator, microRNA-181a, May Indicate Central Nervous System Involvement in Pediatric Leukemia
Authors: Egyed Bálint , Horváth Anna , Semsei Ágnes F. , Szalai Csaba , Müller Judit , Erdélyi Dániel J. , Kovács Gábor T. 
Published: April 2022

Central nervous system (CNS) involvement is a leading cause of therapy-refractory pediatric acute lymphoblastic leukemia (pALL), which is aggravated by underdiagnosing CNS disease with the currently used cell-based approach of cerebrospinal fluid (CSF) diagnostics. Our study focused on developing novel subcellular CNS leukemia indicators in the CSF and the bone marrow (BM) of patients with pALL. Serial liquid biopsy samples (n = 65) were analyzed by Elisas to measure the level of essential proteins associated with blast cell CNS trafficking, vascular endothelial growth factor A (VEGF-A) and integrin alpha 6 (ITGA6). In CSF samples from early induction chemotherapy, VEGF-A concentration were uniformly elevated in the CNS-positive group compared to those patients without unambiguous meningeal infiltration (9 vs Nine patients, Δc = 17.2 pg/ml, p = 0.016). Expression of miR-181a, a VEGFA-regulating microRNA which showed increased level in CNS leukemia in our previous experiments, was then paralleled with VEGF-A concentration. A slight correlation between the levels of miR-181a and VEGF-A indicators in CSF and BM samples was revealed (n = 46, Pearson’s r = 0.36, p = 0.015). After validating in international cohorts, the joint quantification of miR-181a and VEGF-A might provide a novel tool to precisely diagnose CNS involvement and adjust CNS-directed therapy in pALL.
Surfactin Shows Relatively Low Antimicrobial Activity against Bacillus subtilis and Other Bacterial Model Organisms in the Absence of Synergistic Metabolites
Authors: Lilge Lars , Ersig Nadine , Hubel Philipp , Aschern Moritz , Pillai Evelina , Klausmann Peter , Pfannstiel Jens , Henkel Marius , Morabbi Heravi Kambiz , Hausmann Rudolf 
Published: April 2022

Surfactin is described as a powerful biosurfactant and is natively produced by Bacillus subtilis in notable quantities. Among other industrially relevant characteristics, antimicrobial properties have been attributed to surfactin-producing Bacillus isolates. To investigate this property, stress approaches were carried out with biotechnologically established strains of Corynebacterium glutamicum, Bacillus subtilis, Escherichia coli and Pseudomonas putida with the highest possible amounts of surfactin. Contrary to the popular opinion, the highest growth-reducing effects were detectable in B. subtilis and E. coli after surfactin treatment of 100 g/L with 35 and 33%, respectively, while P. putida showed no growth-specific response. In contrast, other antimicrobial biosurfactants, like rhamnolipids and sophorolipids, showed significantly stronger effects on bacterial growth. Since the addition of high amounts of surfactin in defined mineral salt medium reduced the cell growth of B. subtilis by about 40%, the initial stress response at the protein level was analyzed by mass spectrometry, showing induction of stress proteins under control of alternative sigma factors σB and σW as well as the activation of LiaRS two-component system. Overall, although surfactin is associated with antimicrobial properties, relatively low growth-reducing effects could be demonstrated after the surfactin addition, challenging the general claim of the antimicrobial properties of surfactin.
Paediatric brain abscesses in tribal region of India
Authors: Jain Sachin Kumar , Jaiswal Gaurav , Gupta Tarun Kumar , Lodha Krishna Govind , Lohar Vishnu Kumar , Yadav Kaushal 
Published: April 2022

Introduction: Brain parenchymal abscesses are relatively infrequent but potentially serious infections in the paediatric population. Surgical intervention in addition to a prolonged administration of antibiotics is generally appropriate management.
Aims and objective: We performed this study to assess the clinical profile, aetiology and outcome of paediatric brain abscess which are treated surgically only by aspiration in the tribal region of Rajasthan.
Material and method: A single-centre retrospective study was conducted over a 5 year period (2014–2019) in the department of neurosurgery in RNT medical college, Udaipur, Rajasthan. We treated approx 60 patients of which 25 patients treated conservatively and 5 patient treated by craniotomy and abscess excision. So only 30 patient included in our study in which abscess treated by aspiration only. Patients<18 years of age with a confirmed intra-parenchymal abscess were included. Patient records were reviewed for abscess location, microbiology results, Clinical features, Surgical intervention, and outcome using the Glasgow Outcome Score at 3 months.
Result: 11 patients had an abscess in the temporal lobe and Streptococcus was the most common causative micro-organism (n¼15). 25 patients (80%) had an identifiable source which included: ENT infections, congenital cardiac malformations, recent dental surgery and meningitis. The most common symptom is fever f/b headache, seizure and vomiting. But despite previous studies seizure (10/30) presentation is comparatively more. All 30 patients underwent aspiration.
Conclusion: In tribal regions of India ENT infections are a more common source of brain abscess because of poor hygiene and illiteracy and their ignorance of ENT infections and also not taking seriously to fever, headache and other health issues. But at present, there are also decreasing trends of brain abscess by ENT infections and rising trends by congenital heart disease which is a good sign that the health and educational infrastructure is strengthening in the tribal region also.
Lateral orbitotomy in the management of an intra-orbital lipoma
Authors: Cherkaoui Mandour , Houssaine Ait Lhaj El , Adil Khouya Ali , Miloudi Gazzaz , Brahim E.L. Mostarchid 
Published: April 2022

Introduction: Lipomas are benign subcutaneous mass, but the intra-orbital location is rarely reported in the literature and it can resemble a variety of other orbital lesions.
Case report: We describe a 15-year-old girl who presented with left exophthalmia. Orbital magnetic resonance imaging showed an encapsulated intra-conal mass displacing the optic nerve medially, the external right muscle laterally and the globe anteriorly. Excisional biopsy of the mass by lateral orbitotomy approach resolved the exophthalmia, and histology revealed a primary orbital lipoma.
Conclusion: The diagnosis of an intra-orbital lipoma is not easy and the surgical approach represents a challenge to achieve a total excision while avoiding complications.
Proteomics sebagai Metode Identifikasi dalam Ilmu Kedokteran Forensik
Authors: Matialu Dewi D. L. , Kristanto Erwin G. , Mallo Johannis F. 
Published: April 2022

Abstract: DNA analysis is the gold standard in forensic identification, however there are some circumstances in which DNA has been degraded or uninformative that make proteomics has the potential to be an alternative method of forensic identification. This study used a literature review method using four databases (Pubmed, ScienceDirect, Proquest, and SpringerLink). The keywords used in the data search are Proteomics OR Analysis Proteome OR Protein-based Identification AND Forensic Identification. The data selection process using inclusion and exclusion criteria, resulted in 10 literatures (research article). There were 10 literatures that examine the implementation of proteomics as a method of identification in forensic cases using various samples such as hair, bone, muscle, blood plasma, body fluids, stomach content, organ fragments, vomit traces, nail scrapings, and fingerprints with significant research results. The development & implementation of proteomics as a method of forensic identification is currently undergoing several developments using spectrometry (MS) technology. With various significant research results, proteomics has great potential not only in identifying individuals, but in many other ways in forensic medicine.Keywords: Proteomics; Analysis Proteome; Protein-based Identification; Forensic IdentificationAbstrak: Analisis DNA merupakan gold standard dalam identifikasi forensik, tetapi ada beberapa keadaan dimana DNA sudah terdegradasi atau tidak informatif yang menjadikan proteomics berpotensi menjadi sebuah metode alternatif dalam identifikasi forensik. Penelitian ini menggunakan metode literature review dengan pencarian data menggunakan empat database (Pubmed, ScienceDirect, Proquest, dan SpringerLink). Kata kunci yang digunakan dalam pencarian adalah Proteomics OR Analysis Proteome OR Protein-based Identification AND Forensic Identification. Proses seleksi data dengan menggunakan kriteria inklusi dan ekslusi mendapatkan 10 literature (research article). Terdapat 10 literature yang meneliti tentang implementasi proteomics dalam proses identifikasi pada kasus forensik dengan menggunakan berbagai sampel seperti rambut, tulang, otot, plasma darah, cairan tubuh, zat dalam perut, fragmen organ, jejak muntah, kerokan kuku, dan sidik jari dengan hasil penelitian yang signifikan. Perkembangan & implementasi proteomics sebagai metode identifikasi forensik saat ini sudah mengalami beberapa perkembangan dengan menggunakan teknologi mass spectrometry (MS). Dengan berbagai hasil penelitian yang signifikan, maka proteomics memiliki potensi yang besar tidak hanya dalam mengidentifikasi individu, tetapi dalam berbagai hal lain dalam ilmu kedokteran forensik.Kata Kunci: Proteomik; Analisis Proteom; Identifikasi Berbasis Protein; Identifikasi Forensik
Temperature dependence of resistivity and temperature coefficient of a single-crystal bismuth nanowire based on the varying scattering mechanism
Authors: Hasegawa Yasuhiro , Yamashita Daisuke 
Published: April 2022

Abstract
Temperature dependence of resistivity and temperature coefficient of a single-crystal bismuth nanowire was investigated considering the scattering mechanism for each Fermi pocket of the carrier using relaxation time approximation based on the Boltzmann equation. The scattering mechanism of each bismuth carrier was determined according to the relationship between the mean free path of bulk bismuth and nanowire (diameter: 595 and 345 nm). The calculation and experimental results revealed the dominant contribution of the bulk segment in the room-temperature region, influencing the scattering mechanism, whereas the dominant contribution of the wire segment was observed in the lower-temperature region owing to the substantially larger mean free path of the carrier than the wire diameter. Moreover, the temperature coefficient in the lower-temperature region was determined by the effective masses parallel and perpendicular to the wire length, verifying the unique behavior of the temperature dependence of bismuth nanowires with three-dimensional density of state.
A ambivalência discursiva e representacional dos lugares de fala
Authors: Gripp Phillipp , Machado da Silveira Ada Cristina 
Published: April 2022

O artigo discute a noção “lugar de fala”, definida como estratégia enunciativa que consagra a articulação entre a manifestação de um sujeito e sua adscrição identitária em situações de comunicação. Relacionam-se categorias como relações de poder, discurso e identidade para debater a desestima aplicada aos que têm sua voz rejeitada por decorrência de manifestação verbal (realizada em conjunto a outrem) a respeito de uma luta que não corresponde ao lugar social que lhes é atribuído. Argumenta-se quanto Ã lógica ambivalente aplicada no uso da expressão “lugar de fala” no debate teórico e empírico, fragmentado entre perspectivas discursivo-pós-estruturalista e político-representacional.
Posicionamiento discursivo de adultos con discapacidad intelectual frente a los desafíos de una vida independiente
Authors: Jarpa Azagra Marcela , Vega Cordova Vanessa , Spencer González Herbert , Álvarez-Aguado Izaskun , Exss Cid Katherine 
Published: April 2022

El presente estudio tiene como objetivo caracterizar el discurso de un grupo de adultos con discapacidad intelectual desde las modalidades del enunciado y así conocer el posicionamiento discursivo que tienen respecto de los desafíos de la Vida Independiente. Para ello se diseñó una investigación cualitativa que llevó a la realización de seis focus group, donde participaron 8 adultos con discapacidad intelectual. Los temas abordados fueron Vida Independiente, Amistad, Familia, Trabajo y Salud. El corpus total transcrito fue de 88. 494, utilizando el Análisis del Discurso como método de estudio. Entre los principales resultados se destaca la presencia mayoritaria de enunciados epistémicos en los cinco ámbitos temáticos, dando cuenta con esto que ellos conocen y toman conciencia del impacto que tiene en su vidas estos ámbitos de acción. Por otro lado, los enunciados aléticos son lo que presentan menor presencia en el corpus, lo que indica la escasa sensación de proyección que tienen.
Calidad de productos de investigación de revistas académicas arbitradas de México y Guatemala
Authors: Aguilera Arévalo Humberto Emilio 
Published: April 2022

OBJETIVO: evaluar la calidad de los productos de investigación en revistas académicas arbitradas de recién creación de México y Guatemala. MÉTODO: en este estudio se usó un diseño cuantitativo, descriptivo y transversal. Se obtuvo una muestra de conveniencia de 20 estudios de México y 10 de Guatemala, uno por revista añadida en el 2021. Se construyó un índice basado en el modelo de calidad de investigación de Mårtensson et al. (2016). RESULTADOS: se encontró que los aspectos ser creíble, contributiva y alineada, más el indicador de rigurosidad obtuvieron un puntaje bajo. Sin embargo, el aspecto comunicable obtuvo un puntaje alto. CONCLUSIÓN: se concluyó que los estudios de revistas académicas arbitradas de recién creación son de baja calidad. Se recomienda a los entes editoriales abordar esta problemática rechazando trabajos de baja calidad y/o retroalimentando a los autores para mejorar los trabajos. Asimismo, se recomienda a los autores implementar buenas prácticas de investigación.