bluuebunny/crossref_metadata_2025_split huggingface dataset:
Short- versus long-course antibiotic therapy for sepsis: a post hoc analysis of the nationwide cohort study
Authors: Takahashi Nozomi , Imaeda Taro , Nakada Taka‑aki , Oami Takehiko , Abe Toshikazu , Yamao Yasuo , Nakagawa Satoshi , Ogura Hiroshi , Shime Nobuaki , Matsushima Asako , Fushimi Kiyohide 
Published: October 2022

Abstract
Background
The appropriate duration of antibiotic treatment in patients with bacterial sepsis remains unclear. The purpose of this study was to evaluate the association of a shorter course of antibiotics on 28-day mortality in comparison with a longer course using a national database in Japan.

Methods
We conducted a post hoc analysis from the retrospective observational study of patients with sepsis using a Japanese claims database from 2010 to 2017. The patient dataset was divided into short-course (≤ 7 days) and long-course (≥ 8 days) groups according to the duration of initial antibiotic administration. Subsequently, propensity score matching was performed to adjust the baseline imbalance between the two groups. The primary outcome was 28-day mortality. The secondary outcomes were re-initiated antibiotics at 3 and 7 days, during hospitalization, administration period, antibiotic-free days, and medical cost.

Results
After propensity score matching, 448,146 pairs were analyzed. The 28-day mortality was significantly lower in the short-course group (hazard ratio, 0.94; 95% CI, 0.92–0.95; P < 0.001), while the occurrence of re-initiated antibiotics at 3 and 7 days and during hospitalization were significantly higher in the short-course group (P < 0.001). Antibiotic-free days (median [IQR]) were significantly shorter in the long-course group (21 days [17 days, 23 days] vs. 17 days [14 days, 19 days], P < 0.001), and short-course administration contributed to a decrease in medical costs (coefficient $-212, 95% CI; − 223 to − 201, P < 0.001). Subgroup analyses showed a significant decrease in the 28-day mortality of the patients in the short-course group in patients of male sex (hazard ratio: 0.91, 95% CI; 0.89–0.93), community-onset sepsis (hazard ratio; 0.95, 95% CI; 0.93–0.98), abdominal infection (hazard ratio; 0.92, 95% CI; 0.88–0.97) and heart infection (hazard ratio; 0.74, 95% CI; 0.61–0.90), while a significant increase was observed in patients with non-community-onset sepsis (hazard ratio; 1.09, 95% CI; 1.06–1.12).

Conclusions
The 28-day mortality was significantly lower in the short-course group, even though there was a higher rate of re-initiated antibiotics in the short course.
Comparative Effectiveness of Multiple Exercise Interventions in the Treatment of Mental Health Disorders: A Systematic Review and Network Meta-Analysis
Authors: Yu Qian , Wong Ka-Kit , Lei On-Kei , Nie Jinlei , Shi Qingde , Zou Liye , Kong Zhaowei 
Published: October 2022

AbstractBackgroundThe efficacy of exercise interventions in the treatment of mental health disorders is well known, but research is lacking on the most efficient exercise type for specific mental health disorders.ObjectiveThe present study aimed to compare and rank the effectiveness of various exercise types in the treatment of mental health disorders.MethodsThe PubMed, Web of Science, PsycINFO, SPORTDiscus, CINAHL databases, and the Cochrane Central Register of Controlled Trials as well as Google Scholar were searched up to December 2021. We performed pairwise and network meta-analyses as well as meta-regression analyses for mental health disorders in general and each type of mental health disorder, with alterations in symptom severity as the primary outcome.ResultsA total of 6456 participants from 117 randomized controlled trials were surveyed. The multimodal exercise (71%) had the highest probability of being the most efficient exercise for relieving depressive symptoms. While resistance exercise (60%) was more likely to be the most effective treatment for anxiety disorder, patients with post-traumatic stress disorder (PTSD) benefited more from mind–body exercise (52%). Furthermore, resistance exercise (31%) and multimodal exercise (37%) had more beneficial effects in the treatment of the positive and negative symptoms of schizophrenia, respectively. The length of intervention and exercise frequency independently moderated the effects of mind–body exercise on depressive (coefficient = 0.14,p = .03) and negative schizophrenia (coefficient = 0.96,p = .04) symptoms.ConclusionMultimodal exercise ranked best for treating depressive and negative schizophrenic symptoms, while resistance exercise seemed to be more beneficial for those with anxiety-related and positive schizophrenic symptoms. Mind–body exercise was recommended as the most promising exercise type in the treatment of PTSD. However, the findings should be treated with caution due to potential risk of bias in at least one dimension of assessment and low-to-moderate certainty of evidence.Trial RegistrationThis systematic review was registered in the PROSPERO international prospective register of systematic reviews (CRD42022310237).
A modified candy-plug technique to occlude false lumen in aortic dissection
Authors: Palm Erik , Valtola Antti , Manninen Hannu , Saari Petri 
Published: October 2022

Abstract
Purpose
Aim of this technical note article is to introduce a modified, novel way to custom create a candy-plug (CP) device to endovascularly occlude false lumen. The technique is illustrated by a patient case with significant backflow to false lumen (FL). The patient had already undergone surgical repair of the ascending aorta, aortic arch and subsequent TEVAR procedure down to the ostium of the celiac trunk because of type A aortic dissection, but the descending thoracic aorta continued to dilate due to backflow to the FL from an uncovered tear at the level of the renal arteries.

Materials and methods
We modified a Gore Excluder 36–45 mm aortic extender (W. L. Gore & Associates, Inc. Flagstaff, USA) endoprosthesis into a CP device that was subsequently positioned under local anesthesia into the FL of the distal descending thoracic aorta.

Results
In 1 month control the backflow to false lumen had ceased and the aorta had decreased in diameter from 69 to 66 mm, FL from 37 to 34 mm, true lumen (TL) remained the same 32 mm.

Conclusion
We describe a modified, effective candy-plug technique to occlude retrograde false lumen filling in aortic dissection.
A qualitative study of teachers’ and students’ experiences with a context-based curriculum unit designed in collaboration with STEM professionals and science educators
Authors: Kostøl Kristine Bakkemo , Remmen Kari Beate 
Published: October 2022

AbstractContext-based science teaching aims to increase students’ motivation for science learning by demonstrating the personal and societal relevance of science knowledge and practices. However, designing and implementing context-based science teaching can be challenging for teachers. Moreover, context-based learning can be challenging for students as well. The purpose of this study is to describe the experiences of two science teachers and their 16-year-old students after implementing a context-based curriculum unit designed in collaboration with STEM professionals and facilitated by us – science educators and researchers. The research approach is informed by participatory methods involving collaboration between teachers and us as science educators, with the intention of supporting teachers in developing new teaching practices. Data were collected through three focus group interviews with two teachers and two groups of students (N = 9). The transcripts were analysed by inductive coding combined with a refined, literature-driven analysis. Besides positive influences on students’ learning, we found that the context-based curriculum provided an opportunity for the students to contribute to society, which served as another purpose for learning science than traditional science teaching. However, we discuss some challenges that may have implications for this type of collaboration between teachers, science educators, and STEM professionals: the importance of authenticity, teacher involvement in field trip planning, and misalignment between the curriculum unit and assessment.
A case of membranoproliferative glomerulonephritis associated with psoriasis vulgaris
Authors: Jabrane Marouane , Wakrim Abderrahim , Arrayhani Mohammed 
Published: October 2022

Abstract
Background
Psoriasis is a chronic inflammatory disorder of the skin; the hallmark of psoriasis is sustained inflammation that leads to uncontrolled keratinocyte proliferation and dysfunctional differentiation. Psoriasis shows clear autoimmune-related pathomechanisms, in which autoantigen-specific T cells contribute to the development, chronification, and overall course of the disease. Psoriasis is primarily a skin disease, but other internal organs may be involved; affliction of the joints is well established, but kidney involvement is yet to be universally agreed upon, although some recent studies have linked psoriasis to kidney disease and certain glomerular diseases including secondary renal amyloidosis, Ig A nephropathy, and membranous glomerulopathy.

Case presentation and conclusion
In this paper, we report a case of primary membranoproliferative glomerulonephritis (MPGN) with nephrotic impure syndrome in a psoriatic patient. The etiological investigation was negative with normal serum complement and ASO titers and were negative for HBV, HCV, HIV, and ANA. The patient improved on prednisolone and angiotensin-converting enzyme inhibitors. To our best of knowledge, cases of MPGN associated with psoriasis are rare and we would like to shed light on this association.
The incidence of enlarged vestibular aqueduct among hearing-impaired children: hospital-based tertiary care referral center
Authors: Elmoursy Mohamed Mohamed 
Published: October 2022

Abstract
Background
The most common radiologically detectable congenital inner ear anomaly is an enlarged vestibular aqueduct (EVA), which is associated with varying degrees of hearing loss and vestibular disorders. The purpose of this study was to ascertain the enlarged vestibular aqueduct incidence in hearing-impaired children sent to a tertiary care referral center, as well as to describe the audiologic pattern of EVA in those individuals.

Results
In a retrospective study of 3765 hearing-impaired children aged 1 to 10 years, 450 had EVA (11.95%). The EVA was more prevalent in female populations (54.4%). Head trauma was present in 26.7% of cases; a positive family history of EVA was present in 17.8%. The most common associated syndrome was Pendred syndrome. Progressive hearing loss was observed in 25.6% of patients, fluctuant hearing loss in 19.1%, and sudden hearing loss in 2% of the patients.

Conclusion
The most prevalent inner ear anomaly is an enlarged vestibular aqueduct, contributing to 11.9% of the research study. The most common presentation of EVA is hearing loss, which may be stationary, progressive, fluctuant, or sudden onset. CT scan is considered the gold standard radiological test to diagnose EVA in the sagittal or parasagittal plane. Head trauma should be avoided in children with EVA, and close follow-up is essential.
Gender in Post-9/11 American Apocalyptic TV: Representations of Masculinity and Femininity at the End of the World, Eve Bennett (2019)
Authors: DeVries Ben 
Published: October 2022

Review of: Gender in Post-9/11 American Apocalyptic TV: Representations of Masculinity and Femininity at the End of the World, Eve Bennett (2019)
New York: Bloomsbury Academic, 224 pp.,
ISBN 978-1-50133-108-4, h/bk, £110.00, p/bk, £29.99
Menace to Empire: Anticolonial Solidarities and the Transpacific Origins of the US Security State, Moon-Ho Jung (2022)
Authors: Srivastava Saloni 
Published: October 2022

Review of: Menace to Empire: Anticolonial Solidarities and the Transpacific Origins of the US Security State, Moon-Ho Jung (2022)
Oakland, CA: University of California Press, 368 pp.,
ISBN 978-0-52026-748-0, h/bk, £24.00
Phylogeographic patterns in attached and free-living marine macroalga Fucus vesiculosus (Fucaceae, Phaeophyceae) in the Baltic Sea
Authors: Preston Roxana , Seppä Perttu , Schagerström Ellen , Blomster Jaanika 
Published: October 2022

Abstract
Sequencing of a mitochondrial intergenic spacer and 23S subunit was used to investigate the phylogeographic patterns in Fucus vesiculosus. Samples originated from 21 sites spanning six subbasins of the Baltic Sea. We identify a putative ancestral mitochondrial haplotype that entered the Baltic Sea from the Atlantic, colonising extensively throughout the species’ distribution. The dominance of this haplotype is seen in the low overall haplotype diversity (H
d = 0.29). Moreover, there is indication of few spatially aggregated patterns in the deeper demographic time scales (F
ct = 0.040; F
st = 0.049). Tajima’s D (−0.685, p-value 0.297) and Fu’s F
S (0.267, p-value 0.591) showed no significant signals of extreme demographic changes. The Baltic Sea free-living Fucus is confirmed as F. vesiculosus or a closely related species. Haplotype diversities are comparable between forms (attached H
d = 0.306; free-living H
d = 0.268). The relatively short temporal scale for colonisation alongside low variance in the Fucus mitochondrial genome results in a rather panmictic structure across the Baltic Sea. Our data suggest that the mitochondrial intergenic spacer and 23S poorly describe the evolutionary dynamics of Fucus spp. in such a young, postglacial environment, yet this concatenated-barcode advances our understanding of the colonisation dynamics of F. vesiculosus over deeper demographic timescales.
Spatial and temporal variations of macroalgal vegetation in the north-western Red Sea
Authors: Rashedy Sarah H. , El-Mahdy Samia M. , El-Manawy Islam M. , Pereira Leonel 
Published: October 2022

Abstract
Macroalgae play a vital role in marine ecosystems, but human effects are threatening the composition and structure of algal communities. In the present investigation, the spatial and temporal variations of species composition, functional groups and percentage macroalgal cover were studied in relation to seasonal fluctuations of some physicochemical parameters, to determine the ecological status of macroalgae in coastal waters along the coast of the northwestern part of the Red Sea, from November 2020 to October 2021. Fifty-five species of macroalgae were collected and identified from the sites studied. Five functional groups of macroalgae were recognized. Among these were two turf-forming species, 34 species of upright fleshy algae, and three crustose algae. There was a large variation in the cover, as well as in the species richness and assemblage structure of the macroalgae in different sites and seasons. Seasonal changes, determined by environmental conditions, led to small changes in macroalgal cover at different sites, with the growth of some brown macroalgae suppressed by high sea temperatures, whereas some green and red macroalgae, increased in response to increasing temperature and salinity.
Investigation of 7th and 8th Grade Middle School Students’ Environmental Ethics Attitude Levels in Relation to Different Variables
Authors: Tozdan Nilgün , Keleş Özgül 
Published: October 2022

One way to increase people’s positive behaviors toward nature is to ensure that students gain environmental ethics attitude concerning environmental issues. In this regard, the current study investigates the 7th and 8th-grade students’ environmental ethics attitude levels in relation to some variables (grade level, gender, school type). The study employed the survey model, one of the quantitative methods. The current research’s sampling was selected using the stratified sampling method. A total of 723 students (349 seventh graders and 374 eighth graders) attending middle school participated in the current study. The “Environmental Ethics Attitude Scale” was used as a data collection tool in this research. The findings of the current study have revealed that the 7th and 8th-grade students’ environmental ethics attitude levels vary significantly depending on gender in favor of the female students (U(142857) = 560.34; p < 0.001). Moreover, no statistically significant difference was found between the environmental ethics attitude levels of the 7th graders and 8th graders (U(124827) = 63752.00; p > 0.05). In addition, no statistically significant difference was found between the environmental ethics attitude level of the students attending schools located in peripheral districts of the city and that of the students attending schools located in the central districts of the city (U(191838)) = 48993; p > 0.05). The seventh-grade and eighth-grade students’ eccentric environmental ethics attitude mean score and anthropocentric environmental ethics attitude mean score were very close to each other. This shows that the students have environmental ethics attitude yet cannot give up anthropocentric behaviors. Similar studies can be conducted with students from different grade levels.
Two Forms of Humanism: André Malraux and Romain Gary
Authors: Hangouët Jean-François 
Published: October 2022

This article purposes to shed a mutual light on André Malraux’s humanism on the one hand, and on Romain Gary’s on the other hand. Our approach consists in juxtaposing their views on some of those faculties which, in the interaction of the living with the world, seem specific to mankind: the collective faculties of fraternity, culture, and science, the metaphysical abilities to ponder death, cosmos, and evolution.Malraux views fraternity as a “virile” instinct that best manifests itself during warfare, and Gary makes it feminine and akin to “universal love”. While Malraux, most classically, opposes culture to nature, Gary, in an original perspective, sees culture as a new “nurturing environment”. Malraux does not believe in science as a metaphysical incentive, but Gary finds its results stimulating. Malraux tends to think (somewhat paradoxically) about “man’s fate” (at an ontological level) through the (sole) metamorphosis of the works of art as produced in the historic period up to his days. In a broader perspective, Gary considers the biological evolution of mankind over geological ages, methodically starting with the late Devonian when lungless creatures crept up from sea to land, and hopefully envisioning the end result of the twenty thousand years to come. Malraux’s cosmos is a rival to mankind, while Gary sees humanity at home in the universe. Malraux is obsessed with individual death to the point of concluding that any meaning assigned to human lives is nothing but aleatory. Gary has faith instead in the “joy of being” during one’s lifetime, and in the continuous progress of humanity as a species.In such mutual lights, it appears that Malraux’s humanism, not unlike the most melancholic currents of romanticism, is tragic indeed, as many critics have already noted: desolate (man is alone) and devastated (devoid of meaning). As to Gary’s humanism, it comes out as relatable to Julian Huxley’s evolutionary humanism, and no longer as desperate as a certain, inexplicably vivacious, academic tradition still claims it to be. By contrast with Malraux’s, it appears to be actually full of consideration for a wide variety of human interests, yearnings and dreams. It is tactfully expressed in a way that stimulates hope. And its fictionalized form is masterly, not only in terms of novel-writing (Gary’s books being so unlike thesis novels) but also in terms of analytical thinking and philosophical foundation.
Two Cinemas: Sierra de Teruel by André Malraux and Birds in Peru by Romain Gary
Authors: Hangouët Jean-François 
Published: October 2022

This communication reviews some of the aesthetical and circumstantial characteristics of André Malraux’s only film, Sierra de Teruel (1939), also known as Espoir (Hope, 1945), and of Romain Gary’s first film, Les oiseaux vont mourir au Pérou (Birds in Peru, 1968). As regards Espoir, our observations are based on the 1939 and 1945 versions of the film, now of easy access, and on the abundant and reliable academic literature published about it. Birds in Peru, conversely, is a far lesser-known and lesser-documented work. Screenings of Gary’s film are all too rare indeed nowadays and, but for a few highly specialized references, its appraisal still consists in a short set of irrelevant legends, continually retold by biographers and academics alike despite their blatant discrepancies with historical evidence, with the film itself, and with Gary’s literary works in general. Ours are first-hand observations: in our possession is a release print, which we had digitized and can thus view at will. In addition, we have explored a variety of source materials in cinematographic archives and historical newspapers.Valued either as one of Malraux’s works or as an example of antifascist propaganda, it is lucky that Sierra de Teruel can still be viewed today, despite the political censorship that prevented its release in September 1939 and despite the destruction of all prints but two by the German occupant in France during WWII. Equally fortunate are the facts that moralistic considerations failed to stop the release of Birds in 1968 and that prints of it aren’t all lost. Gary scholars will find food for thought in it, as well as semioticians, Gary’s film being just as allegorical as his contemporary novel The Dance of Genghis Cohn. More generally still, both works, no naïve executions, bring evidence that talented writers can change media effectively. Far from being literal adaptations, their two films narrate free and inspired versions of stories already told in the written form. Their filming style is creative, their technique masterly. Their ease with the cinematographic medium allows them to reemploy and expand devices known to make their personal literary signature. Such as the striking juxtaposition of action and scenery used by Malraux to convey his metaphysics of disjunction between man and nature. Such as the subtle art of immigrating lexical components from other tongues and languages, idiosyncratic to Gary’s novel writing. Even elements of their respective forms of humanism show through their films.
Decision Support Method in the Assessment of Nuclear Knowledge Management using Fuzzy Logic
Authors: Grecco Claudio Henrique dos Santos , Viana de Souza Jaqueline Tavares , Rodrigues Carvalho Paulo Victor , Nunes Cosenza Carlos Alberto 
Published: October 2022

The knowledge of workers constitute as valuable resources, as they enable organizations to perform their functions successfully. However, there are conditions that favor the loss of this knowledge in organizations, as for example, the natural aging of workers and consequently the retirement and staff turnover. Then, it becomes important for organization to seek the preservation these knowledge. For a successful implementation of Knowledge Management (KM), it is important to identify the barriers or critical factors that affect the success of the KM process.
From the perspective of the nuclear organizations, no systematic framework exists on characterizing a set of critical success factors (CSFs) for implementing KM. Furthermore, the CSFs assessment deals with uncertainty and imprecision of human judgments. In this context, this paper presents a decision support method using CSFs and logic fuzzy to assess the KM in nuclear organizations. Fuzzy theory is essentially used in mapping quantitative models for decision support and representation methods in imprecise and uncertain environments. The decision support method was applied at the Laboratory of Human-Systems Interfaces of the Nuclear Engineering Institute. The results showed that the method is a good assessment tool for the elaboration of nuclear knowledge management strategies.