bluuebunny/crossref_metadata_2025_split huggingface dataset:
Vegetative propagation of bird’s-foot trefoil (Lotus corniculatus L.) using different rooting agents
Authors: Castillo-Cabrera Cristian , Mendoza-Pedroza Sergio I. , Escalante-Estrada José A. S. , García-De los Santos Gabino , Pro-Martínez Arturo , González-Cerón Fernando 
Published: August 2022

Objective: To evaluate the growth dynamics based on the dry matter production of Lotus corniculatus L. variety 202700 and its morphological composition.
Design/Methodology/Approach: The study was carried out in the glass greenhouses of the Colegio de Postgraduados in Montecillo, Texcoco, Edo. Mexico, from December 2020 to May 2021. The effect of indole butyric acid (IBA) growth promoter in solid presentation Radix 1500 and liquid Radix T 3000 (S+ESolid and S+ELiquid) and a control (Substrate) was evaluated., a completely randomized design with three replicates was used, each with twenty pots as replicates. 1300 pots were planted, of which 20 of each treatment were taken monthly (30, 60, 90, 120 and 150 days) for subsequent data recording.
Results: S+ESolid was the one that presented the highest values ​​followed by S+ELiquid and Witness (S) respectively.
Study Limitations/Implications: Destructive sampling of less than 30 days or greater than 150 days was not considered.
Findings/Conclusions: The plants with the application of 1500 ppm of IBA registered the greatest response in terms of variables: number of leaves, number of stems, leaves (g), stems (g), roots (g), root height (cm), root volume (cm3), greenness index, leaf area (cm2 /g) and plant height (cm), with respect to the rest of the treatments.
Meat production and quality of rabbits fed different diets and a biological activator
Authors: Mijangos-Santos Nagai A. , Villegas-Aparicio Yuri , Gómez-Vázquez Armando , Hernández- Bautista Jorge , Govea-Luciano Alejandra , Montañez-Valdez Oziel D. , Rubio-Arias Hector O. 
Published: August 2022

Objective: Evaluate the effect of four diets on the productive performance of rabbits, carcass yields, meat color and pH.
Design/methodology/approach: Thirty-two California breed rabbits were randomly assigned to each of the following diets: “commercial feed” alone; “commercial feed + biological-activator”; “alfalfa forage + biological activator” and “integral feed + biological-activator”. In the animals were evaluated: daily weight gain (DWG), feed conversion (FC), daily feed intake (DFI), body weight (BW), empty body weight (EBW) and carcass yields. In the meat were determined: pH, luminosity, red color and yellow color. Means were compared using the Duncan test (α = 0.05).
Results: The commercial feed diets showed (P < 0.05) higher DWG, DFI, BW and EBW than he other diets. The “commercial feed + biological-activator” diet produced (P < 0.05) in general, higher carcass weights and yields than the alfalfa-based diet, which produced (P < 0.05) a higher pH and yellow color in the meat than the “commercial feed alone” diet.
Study Limitations/Implications: The feeding of the rabbits by adding the biological-activator improves the performance, the color of the meat and the pH.
Findings/conclusions: to add the biological-activator into the commercial feed improves the yield of empty body weight; to add it into the alfalfa forage and compare it with the commercial feed (alone or with activator) improves both the color of meat (making it more yellow) and the pH (making it higher).
Peran Brand Image Sebagai Strategi Komunikasi Pemasaran Iklan Kecik Harian Suara Merdeka
Authors: Damayanti Meiske Nadia , Zulfiningrum Rahmawati 
Published: August 2022

Before doing marketing activities, several marketing communication strategies are needed. Suara Merdeka, as a legendary newspaper company in Central Java, applies the STP (Segmenting, Targeting, Positioning) strategy to support the role of Suara Merdeka brand image to attract public interest in kecik advertisements. This research method is descriptive qualitative, using the interviews data. The results of this data analysis are then applied using a segmenting strategy where Suara Merdeka uses demographic, geographic, and behavioral segmentation. For the targeting strategy, Suara Merdeka uses Selective Specialization where the company determines the market segment according to its objectives and resources. Thus, two main targets of Suara Merdeka market were formed, namely the Existing Brand and the New Brand. The targeting strategy is narrowed down to several categories such as automotive; house; career; as well as sundries such as services, loss information, and building property materials. In its positioning strategy, Suara Merdeka Merdeka uses its image as a legendary company with a distribution in Central Java, with six regional offices in 29 districts in Central Java. The role of brand image using the STP strategy able to influence consumer interest in placing kecik advertisements at Suara Merdeka.
Abstrak
Sebelum melakukan kegiatan pemasaran, dibutuhkan beberapa strategi komunikasi pemasaran agar tujuan perusahaan dapat tercapai. Suara Merdeka sebagai perusahaan koran legendaris di Jawa Tengah, menerapkan strategi STP (Segmenting, Targeting, Positioning) sebagai pendukung peran brand image Harian Suara Merdeka. Penelitian ini bertujuan mengetahui peran brand image Suara Merdeka menggunakan strategi segmenting, targeting, dan positioning yang dilakukan oleh Suara Merdeka untuk menarik minat masyarakat agar melakukan tindakan pemasangan iklan kecik. Metode penelitian ini adalah deskriptif kualitatif, dengan menggunakan data wawancara. Hasil analisis data ini kemudian diterapkan menggunakan strategi segmenting dimana Suara Merdeka menggunakan segmenting demografis, geografis, dan perilaku. Untuk strategi targeting, Suara Merdeka menggunakan Selective Specialization dimana, perusahaan menentukan segmen pasar yang sesuai dengan tujuan serta sumber daya yang dimiliki. Sehingga terbentuk dua target utama pasar Suara Merdeka, yaitu Existing Brand dan New Brand. Strategi targeting tersebut mengerucut pada beberapa kategori seperti otomotif; griya; karir; serta serba-serbi seperti jasa, info kehilangan, dan bahan properti bangunan. Pada strategi positioning, Suara Merdeka Merdeka menggunakan citra nya sebagai perusahaan legendaris dengan persebaran di Jawa Tengah, dengan memiliki enam kantor wilayah di 29 Kabupaten di Jawa Tengah. Peran brand image menggunakan strategi STP mampu mempengaruhi minat konsumen untuk melakukan pemasangan iklan kecik di Suara Merdeka.
Hashtag dan Community Engagement Konten Perkembangan Ekonomi Kreatif Cirebon pada Media Sosial Instagram
Authors: Kushardiyanti Dessy , Suryadi  , Khotimah Novy Khusnul 
Published: August 2022

This research traces and analyzes the content of Instagram's social media to see community engagement through a series of online news on Instagram, especially in the creative economy sector. Descriptive qualitative-based research method with content analysis approach by searching # (hashtag) with the keyword Cirebon and grouping several accounts to see engagement based on followers and number of uploads to see activity on the content through captions or image descriptions as well as community involvement as Instagram users. The results of the study state that the role of Instagram social media in terms of content analysis has a major impact and influence on the economic development in the city of Cirebon in terms of opinions, invitations, and education of several Instagram account users because it can be seen that there is community engagement in several uploads to advance the city of Cirebon as a service city in Indonesia. The participation of business actors/entrepreneurs makes a major contribution to the development economy and creative economy because of the findings and the number of entrepreneurs who have goods and services with their own uniqueness and the large use of social media Instagram as one of the uses of technology seen from Rostow's economic theory of development.
Abstrak
Penelitian ini menelusuri dan menganalisis konten media sosial Instagram untuk melihat community engagement melalui serangkaian berita-berita online di Instagram, khususnya di sektor ekonomi kreatif. Metode penelitian berbasis kualitatif deskriptif dengan pendekatan analisis konten, menelusuri # (hashtag) dengan kata kunci Cirebon dan melakukan pengelompokan beberapa akun guna dilihat engagement berdasarkan followers dan jumlah uggahan untuk melihat aktivitas pada konten tersebut melalui caption atau deskripsi gambar serta keterlibatan masyarakat sebagai pengguna Instagram. Hasil penelitian menyebutkan peran sosial media Instagram ditinjau dari analisis konten memberikan dampak dan pengaruh besar terhadap ekonomi pembangunan di kota Cirebon ditinjau dari pendapat, ajakan, edukasi beberapa pengguna akun Instagram karena terlihat adanya community engagement di beberapa unggahan untuk memajukan kota Cirebon sebagai kota jasa di Indonesia. Peran serta pelaku usaha/wirausaha memberikan kontribusi besar terhadap ekonomi pembangunan dan ekonomi kreatif karena temuan dan banyaknya pelaku wirausaha memiliki barang dan jasa dengan keunikan masing-masing serta besarnya penggunaan sosial media Instagram sebagai salah satu pemanfaatan teknologi dilihat dari teori ekonomi pembangunan Rostow.
Makna Tasamuh pada Fungsi Ganda Media Sosial bagi Pemain Sepakbola Liga Inggris
Authors: Fauzy Emqi Muhammad , Prasetya Widodo Herru , Ghofur M. Abdul 
Published: August 2022

Social media has a dual function for several parties that are involved in the world of social media in their daily lives. In its use, social media has dual functions, where it is could become the supporter system and also an obstacle to the occurrence of a social phenomenon. Including in the case of racism that has recently occurred in the English football league, which has led to a boycotting some social media platforms as an action to demand firmness from the platform regarding the racism that pervades within. Therefore, the existence of Tasamuh is needed to implement a fair game. Including in the world of football itself where there is the term Fair Play which supports the existence of tasamuh in it. Fair Play or fair play is applied thoroughly both outside and inside a match as well as in the use of social media.
Abstrak
Media sosial memiliki fungsi ganda bagi beberapa pihak yang di dalam kesehariannya berkecimpung dalam dunia media sosial. Dalam penggunaannya, media sosial mempunyai fungsi ganda, dimana ia adalah suatu pendukung dan juga penghambat akan terjadinya suatu gejala dalam fenomena sosial. Termasuk dalam kasus rasisme yang akhir-akhir ini terjadi didalam lingkungan sepak bola Inggris, yang mana menyebabkan terjadinya aksi boikot terhadap platform-platform media sosial sebagai aksi untuk menuntut suatu ketegasan dari pihak platform akan adanya rasisme yang menjalar didalamnya. Oleh karena itu adanya Tasamuh diperlukan untuk menerapkan suatu permainan yang adil. Termasuk pula dalam dunia sepak bola itu sendiri dimana terdapat istilah Fair Play yang mendukung adanya tasamuh didalamnya. Fair Play diterapkan secara menyeluruh baik diluar maupun didalam suatu pertandingan juga dalam penggunaan media sosial.
Spontaneous Browning of White Adipose Tissue Improves Angiogenesis and Reduces Macrophage Infiltration After Fat Grafting in Mice
Authors: Lin Jiayan , Zhu Shaowei , Liao Yunjun , Liang Zhuokai , Quan Yuping , He Yufei , Cai Junrong , Lu Feng 
Published: August 2022

Background: Fat grafting is a frequently used technique; however, its survival/ regeneration mechanism is not fully understood. The browning of white adipocytes, a process initiated in response to external stimuli, is the conversion of white to beige adipocytes. The physiologic significance of the browning of adipocytes following transplantation is unclear.Methods: C57BL/6 mice received 150 mg grafts of inguinal adipose tissue, and then the transplanted fat was harvested and analyzed at different time points to assess the browning process. To verify the role of browning of adipocytes in fat grafting, the recipient mice were allocated to three groups, which were administered CL316243 or SR59230A to stimulate or suppress browning, respectively, or a control group after transplantation.Results: Browning of the grafts was present in the center of each as early as 7 days post-transplantation. The number of beige cells peaked at day 14 and then decreased gradually until they were almost absent at day 90. The activation of browning resulted in superior angiogenesis, higher expression of the pro-angiogenic molecules vascular endothelial growth factor A (VEGF-A) and fibroblast growth factor 21 (FGF21), fewer macrophages, and ultimately better graft survival (Upregulation, 59.17% ± 6.64% vs. Control, 40.33% ± 4.03%, *p &lt; 0.05), whereas the inhibition of browning led to poor angiogenesis, lower expression of VEGF-A, increased inflammatory macrophages, and poor transplant retention at week 10 (Downregulation, 20.67% ± 3.69% vs. Control, 40.33% ± 4.03%, *p &lt; 0.05).Conclusion: The browning of WAT following transplantation improves the survival of fat grafts by the promotion of angiogenesis and reducing macrophage.
Prognostic value of post-discharge depression in patients recently hospitalized with acute heart failure
Authors: Li Junlei , Jiang Chao , Liu Rong , Lai Yiwei , Li Li , Zhao Xiaoyan , Wang Xiaofang , Li Ling , Du Xin , Ma Changsheng , Dong Jianzeng 
Published: August 2022

BackgroundDepression is a prevalent comorbidity in patients with heart failure (HF). However, data regarding the prognostic significance of depression during the early post-discharge period in patients hospitalized with acute HF, regardless of left ventricular ejection fraction (LVEF), were scarce.Methods and resultsThe Heart Failure Registry of Patient Outcomes (HERO) study is a prospective, multicenter study of patients hospitalized with acute HF in China. At the first follow-up after discharge (median 4.0, interquartile range [IQR]: 2.4–6.1 weeks), depressive symptoms over the past 2 weeks were assessed using the Patient Health Questionnaire-9 (PHQ-9). Of 3,889 patients, 480 (12.3%) patients had depression (PHQ-9 score ≥ 10). A total of 3,456 patients (11.4% with depression) were included in the prospective analysis. After a median follow-up of 47.1 weeks (IQR: 43.9, 49.3) from the first follow-up, 508 (14.7%) patients died, and 1,479 (42.8%) patients experienced a composite event (death or HF rehospitalization). Cox proportional hazards models were used to assess the association of post-discharge depression with adverse events. After adjustment, post-discharge depression was associated with an increased risk of all-cause mortality (hazard ratio [HR] 2.38 [95% confidence interval (CI): 1.93–2.94]; p &lt; 0.001) and the composite event (HR 1.78 [95% CI: 1.55–2.05]; p &lt; 0.001). A per scale point increase in PHQ-9 score (ranging from 0 to 27 points) was associated with a 7.6% increase in all-cause mortality (HR 1.08 [95% CI: 1.06–1.09]; p &lt; 0.001). In the subgroup analysis, the association between depression and the composite event was significantly stronger in relatively younger patients (&lt; 75 vs. ≥ 75 years; p for interaction = 0.011), and the association between depression and all-cause mortality was significantly stronger in patients with preserved ejection fraction than in those with reduced ejection fraction (p for interaction = 0.036).ConclusionPost-discharge depression in patients recently hospitalized with acute HF is associated with an increased risk of adverse events, regardless of LVEF. Screening for depressive symptoms during the early post-discharge period may help to better identify high-risk patients and tailor patient management. Further studies are needed to determine how regular depression screening can help improve patient management and clinical outcomes.
The overlooked problem among surgical patients: Preoperative anxiety at Ethiopian University Hospital
Authors: Woldegerima Berhe Yophtahe , Belayneh Melkie Tadesse , Fitiwi Lema Girmay , Getnet Marye , Chekol Wubie Birlie 
Published: August 2022

IntroductionAnxiety was repeatedly reported as the worst aspect of the perioperative time. The objective of this study was to assess the prevalence of preoperative anxiety among adult surgical patients at University of Gondar Comprehensive Specialized Hospital (UoGCSH), Northwest Ethiopia.MethodologyA hospital-based cross-sectional study was conducted among surgical patients at the university hospital. After obtaining ethical approval, 407 surgical patients were approached during the preoperative period. Preoperative anxiety was assessed by State-Trait Anxiety Inventory. The association between variables was determined by using binary logistic regression analysis. Strength of association was described in adjusted odds ratio (AOR), and a p-value &lt; 0.05 at 95% confidence interval was considered statistically significant.ResultsA total of 400 patients were included in this study with a 98.3% response rate. Preoperative anxiety was observed among 237 (59.3%) patients, and the median (IQR) STAI score was 50 (40–56.7); age, ≥ 60 years (AOR: 5.7, CI: 1.6–20.4, P: 0.007); emergency surgery (AOR: 2.5, CI: 1.3–4.7, P: 0.005); preoperative pain (AOR: 2.6, CI: 1.2–5.4, P: 0.005); and rural residency (AOR: 1.8, CI: 1.1–2.9, P: 0.031) were found significantly associated with preoperative anxiety.ConclusionThe prevalence of preoperative anxiety among surgical patients was high. Older age (≥ 60 years), emergency surgery, preoperative pain, and rural residency were found significantly associated with preoperative anxiety. Assessment for preoperative anxiety should be a routine component of preoperative assessment of both elective and emergency surgical patients. Preoperative pain should be appropriately managed as it can help to reduce preoperative anxiety. Optimal anxiety reduction methods should be investigated and implemented in the hospital.
Function matters: Coronavirus cross-binding antibodies do not cross-neutralize
Authors: Farcet Maria R. , Schwaiger Julia , Karbiener Michael , Kreil Thomas R. 
Published: August 2022

BackgroundDuring the current pandemic, the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) neutralization capacity of the immunoglobulin (IG) supply has changed from undetectable for lots manufactured from plasma collected before the pandemic, to now highly potent.ObjectiveAs antibodies induced by exposure to or vaccination against coronaviruses were shown to be cross-coronavirus reactive, it was of interest to understand whether SARS-CoV-2 neutralizing antibodies would result in increased functional IG potency also against seasonal coronaviruses.MethodsIG lots from US plasma collected before SARS-CoV-2 emerged and collected during the pandemic were analyzed by live virus neutralization assay for SARS-CoV-2 and seasonal human coronaviruses (HCoVs) NL63 and OC43 neutralizing antibody content.ResultsPre-pandemic IG showed no SARS-CoV-2 neutralizing antibody titers. However, IG lots produced from plasma of post-coronavirus disease 2019 (COVID-19) individuals exhibited robust anti-SARS-CoV-2 potency (1,267 IU/ml) which further increased ~4-fold in pandemic IG lots reaching a mean titer of 5,122 IU/ml. Nonetheless, neutralizing antibody potencies to the HCoVs NL63 and OC43 remained stable over this period, i.e., have not increased correspondingly.ConclusionThe present results show that cross-coronavirus-reactive antibodies are not cross-neutralizing, i.e., SARS-CoV-2 antibodies do not neutralize seasonal coronaviruses NL63 and OC43.
Performance of quantitative measurements in [18F]fluorocholine positron emission tomography/computed tomography for parathyroid imaging (P2TH study)
Authors: Jacquet-Francillon Nicolas , Morelec Isabelle , Germain Natacha , Prades Jean-Michel , Habouzit Vincent , Mariat Christophe , Bonnefoy Pierre-Benoit , Prevot Nathalie 
Published: August 2022

Objective[18F]Fluorocholine positron emission tomography/computed tomography (PET/CT) is used frequently in addition to [99mTc]Tc-Sestamibi scintigraphy and ultrasonography for the location of hyperfunctioning parathyroid glands. The aim of this study is to evaluate the performance of quantitative criteria in [18F]fluorocholine PET/CT for localization of hyperfunctioning parathyroid glands. The secondary objective is to highlight a correlation between the detection rate of [18F]fluorocholine PET/CT and serum parathyroid hormone (PTH) level.Materials and methodsIn two academic centers, we retrospectively included patients with biological hyperparathyroidism (HPT) and who had [18F]fluorocholine PET/CT. After a visual analysis, to measure the overall performance of [18F]fluorocholine PET/CT, a blind reading was carried out with standardized measurements of maximum standardized uptake value (SUVmax), liver ratio, thyroid ratio, and size ratio. We analyzed the quantitative criteria of [18F]fluorocholine PET/CT compared to the histological results, in particular to identify differences between adenomas and hyperplasias. We compared the performance of each quantitative criterion to the overall sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of [18F]fluorocholine PET/CT. The detection rate of hyperfunctioning parathyroid glands was calculated in subgroups of serum PTH level.ResultsThe quantitative criteria in [18F]fluorocholine PET/CT were measured for 120 patients (135 lesions). The areas under the receiver operating characteristic (ROC) curve representing SUVmaxand liver ratio were significantly increased. The optimal cut-off values represented by the maximum Youden index was &gt;4.12 for SUVmaxand &gt;27.4 for liver ratio. Beyond certain threshold values of SUVmax(&gt;4.12) or liver ratio (&gt;38.1), all the lesions were histologically proven adenomas. SUVmaxand liver ratio were significantly higher for adenomas than for hyperplasias and differential diagnosis (p= 0.0085 andp= 0.0002). The positivity of [18F]fluorocholine PET/CT was correlated with PTH level. Detection rates were 55.56, 75.56, and 87.5%, respectively, for serum PTH &lt; 70, 70 to 120, and &gt;120 ng/ml.ConclusionSemi-quantitative measurements (SUVmaxand liver ratio) should be considered as additional tools in interpretation of [18F]fluorocholine PET/CT. These quantitative parameters have lower overall performance but higher specificity than overall visual analysis in identifying an adenoma. Above certain threshold values, all lesions are adenomas. [18F]fluorocholine PET/CT confirms excellent performance for the detection of hyperfunctional parathyroids. For serum PTH levels &lt; 70 ng/ml, the detection rate of [18F]fluorocholine PET/CT is strongly decreased.