bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visualizing Groundwater Dispersion: Laboratory Exercise on Dispersivity with Hands-on and Online Students
Authors: Korom Scott 
Published: July 2022

Longitudinal groundwater dispersion is measured by calculating the spreading of a solute in the direction of groundwater flow as a function of time, with dispersivity being the plume dispersion divided by the groundwater velocity. Two-dimensional physical groundwater flow models were used in a laboratory exercise to illustrate groundwater dispersion to hands-on and online students. Learning assessment of the pedagogical value of the laboratory exercise was based on a student survey and an independent laboratory assignment graded by the course instructor. Both tools indicated that student learning was effectively enhanced by the dispersivity laboratory exercise; however, it was more effective for the hands-on students.
Assessment of Engineering Entrepreneurship Intentions Among Engineering Students of Osun State University, Nigeria
Authors: Idris Musibaudeen Olatunde , Adeboye Busayo Sunday , Adeyemi Oluseyi Afolabi , Abanikannda Mutahir Oluwafemi , Lawal Nureni Adekunle , Lawal Muyideen Olalekan 
Published: July 2022

Entrepreneurship is the major solution to the unemployment problem that has resulted to multifaceted socio-economic challenges in the developing worlds. If engineer becomes entrepreneur, this will not only create jobs but promote technological development and a sustainable national economic growth is guaranteed. The process of entrepreneurship starts from the development of intention to embark on such a venture, hence this study assessed the entrepreneurial intentions of the engineering students in the universities. To accomplish this task, Ajzen theory of planned behaviour is applied. A survey was conductor at the faculty of engineering, Osun State University, Osogbo, Nigeria through a structured questionnaire administered to 470 engineering students in 2021. The data collected was analysed using Statistical Product and Service Solution (SPSS) version 20. The results of the descriptive and regression analyses using the SPSS show that engineering courses are mostly study by the male gender and further revealed that entrepreneurial intentions could be statistically investigated using the Ajzen theory. The results specifically revealed that personal attitude, subjective norms and perceived behavioural control are statistically significant in determining the entrepreneurial intentions of engineering students, while the level of study is insignificant. Based on these results, recommendations for the government, heads of engineering faculty, educators in the fields of engineering and entrepreneurship were provided
Approach for Eliciting Learners' Preferences in Moocs Through Collaborative Filtering
Authors: Naji Khadija , Ibriz Abdelali 
Published: July 2022

Les MOOC (massive open online courses) deviennent rapidement des incontournables pour assurer la continuité pédagogique et accompagner la vie et les modes de travail futurs. Il est donc nécessaire que les MOOC s'éloignent de leur ancien modèle. Ce cadre présentera un système de recommandation basé sur un algorithme qui utilisera un filtrage collaboratif basé sur les préférences des apprenants MOOC. Le filtrage collaboratif est une technique permettant d'anticiper les intérêts d'un utilisateur en étudiant les préférences des utilisateurs similaires à l'individu en question. Cette approche assure l'analyse de nombreux éléments en utilisant le choix de notation des participants.Un système de recommandation devient de plus en plus courant dans les activités d'étude en ligne ; nous voulons étudier comment cela pourrait aider à l'apprentissage et favoriser une implication plus efficace.
Nous baserons notre système de recommandation proposé sur l'évaluation du contenu du cours. L'idée est que les apprenants évaluent les cours et le contenu auxquels ils se sont inscrits sur la plateforme entre 1 et 5. Suite à l'évaluation, nous extrayons les données dans un fichier de valeurs séparées par des virgules (CSV) et utilisons la programmation Python pour fournir des recommandations à l'aide des données de apprenants avec des modèles de notation similaires. Le but était d'utiliser la programmation Python pour proposer des cours à différents utilisateurs en mode éditeur de texte. Nous utiliserons des modèles d'évaluation similaires via un filtrage collaboratif pour recommander des cours à divers apprenants, améliorant ainsi leur expérience d'apprentissage et leur passion.
Le lettré chinois : designer ignoré des traductions
Authors: Bonnard Émilie 
Published: July 2022

Le regard de l’Occident sur la Chine ne cesse de se modifier, en fonction des échanges entre les deux pays, et des émotions qui étreignent les protagonistes. Dans un premier temps, l’augmentation des échanges a surtout favorisé la traduction des textes occidentaux en mandarin. Ensuite, l’attrait croissant pour la culture chinoise a conduit à l’augmentation du nombre de sinologues et à une diversification des traductions des textes chinois en Occident. La traduction des récits consacrés à la création, avant 1911 et l’avènement de la République, a révélé la personnalité complexe du lettré qui ne se limitait probablement pas à sa position de fonctionnaire administratif. Il apparaît comme un artiste et intellectuel, un savant ingénieux, parfois jardinier (Ji Chen) ou botaniste (Chen Haozi), ou encore inventeur (Li Yu). Les récits, marginaux, selon les sinologues francophones, de ces hommes créatifs et inventifs, à la croisée des disciplines, résonnent avec les discours des designers contemporains. La traduction francophone des récits de lettrés que nous avons étudiés, relate le développement d’un art de vivre avec le parfum particulièrement raffiné. Les lettrés concevaient des ustensiles, des usages, des circonstances, pour vivre harmonieusement dans une ambiance parfumée. Aujourd’hui, dans ces traductions, doit-on qualifier ce personnage de « lettré », de « designer », ou encore plus précisément de « designer olfactif » ? Un dialogue entre sinologues et designers semble s’imposer.
Zu, ou les possibles d’une pensée japonaise du design
Authors: Maudet Nolwenn 
Published: July 2022

Si la traduction des classiques anglais du design en français reste lacunaire, les pensées du design développées en dehors de l’anglais sont presque invisibles en France. En s’appuyant sur un exemple d’une pensée du design japonaise, cet article développe une réflexion sur quelques-unes des possibilités et des limites d’une pensée du design en dehors de l’anglais. Le texte présenté dans cet article, écrit en 1981 par le designer Tadanori Nagasawa lors de ses recherches au Royal College of Art, introduit la notion de zu 図, un terme japonais a priori intraduisible qui permet de décrire « presque toutes les formes de représentations graphiques en deux dimensions, autres que les images picturales et la simple prose ». Après un premier travail réflexif de traduction et d’acculturation en français de cette notion qui permet de penser le design de manière décloisonnée à travers ses outils de représentation graphique, on interroge la possibilité même d’une pensée non anglo-centrée du design. Car, la pensée de Nagasawa, plus qu’une pensée du design japonaise, est une pensée bilingue, se construisant sous le regard de l’anglais dans un mémoire écrit avant tout pour des lecteurs anglophones. Or, une seconde analyse du texte de Nagasawa révèle comment le développement de sa théorie du zu s’appuie sur les particularités du système d’écriture de la langue japonaise.
Traductologie et théories du design : des « arts exacts » ?
Authors: Chomarat-Ruiz Catherine 
Published: July 2022

Dans quelle mesure traductologie et théories du design peuvent-elles être scientifiques ? C’est en partant des métaphores utilisées dans le domaine de la traductologie et de leur éventuelle transposition au design et à ses théories que cette question émerge. Cet article éclaire les fondements de cette transposition et, ce faisant, met au jour les faiblesses épistémologiques que ces deux disciplines partagent au point que la première pourrait être considérée comme paradigmatique pour la seconde. Sans clore le débat, il encourage son lecteur à se demander s’il ne vaudrait pas mieux renoncer à toute scientificité pour penser ces deux disciplines comme des « arts exacts ».
Des réductions en art aux traductions incidentes : le décentrement d’un design tactique
Authors: Marion Grégory 
Published: July 2022

Nourri des travaux de Michel de Certeau soutenant la capacité de la « culture ordinaire » à faire incidence sur l’ordre de la production industrielle (cf. le travail de l’auteur sur les « manières de faire » et les « pratiques quotidiennes » dans L’Invention du quotidien, 1980), cet article propose de frotter de façon spécifique – dans le champ des arts, des techniques et du design – textes, objets ou pratiques, afin de dégager des lignes de discernement et ménager des ouvertures. Tenant à l’attention certalienne à l’égard des procédures « tactiques », il s’agit, pour soutenir l’hypothèse de traductions en design, de mettre en discussion le paradigme de « la réduction en art », c’est-à-dire l’emprise de doctrines qui confisquent des « arts de faire » afin de les reformuler en discours. Tel renversement critique, dégageant les multiples usages qui traduisent quotidiennement les produits de consommation courante en tournures et phrasés, ne manque pas d’interroger la tâche du designer.
Antidiabetic and Antiradical Effects of Garcinia kola Seeds in Dexamethasone-Induced Hyperglycemic Rats
Authors: Nkono Ya Nkono Barnabé Lucien , Rouamba Ablassé , Kinyok Mc Jesus , Omokolo Jean Guy Stéphane , Tcheudi Balthazar Tchouanka , Tigui Benjamin Arnaud , Dzeufiet Paul D. Djomeni , Sokeng Sélestin Dongmo , Kamtchouing Pierre 
Published: July 2022

Background
In traditional medicine, the maceration of seeds of Garcinia kola (GK) is used to treat various diseases including diabetes. In traditional pharmacopoeia, GK seeds are used to strengthen the immune system and as a stimulant and aphrodisiac.

Aims
This study aimed to evaluate the antidiabetic free radical scavenging effects of the hydroalcoholic extract of GK seeds (HAEGS) in a dexamethasone-induced hyperglycemic (DexIH) rat model.

Settings and Design
This study was an interventional study.

Subjects and Methods
Here using in vivo model, we assessed some pharmacological properties of HAEGS in DexIH rat. Hypoglycemia, antihyperglycemia, spasmolytic and laxative activities were also evaluated in DexIH. In vitro study assessed antiradical activity. The HAEGS was obtained by decoction introducing 250 g with water–ethanol mixture (30:70). The plant extract was administered to the animals at doses of 50 (GK50) and 100 (GK100) mg/kg body weight. All animal experiments were in accordance with ARRIVE guidelines and were performed in accordance with the scientific procedures of UK Animals. Antiradical activity of GK was assessed in vitro by inhibition of the activity of 2,2-diphenyl-1-picrylhydrazyl.

Statistical Analysis Used
Statistical analysis was performed using GraphPad Prism 5.03 software, and P values less than 0.05 were considered statistically significant.

Results
At doses 50 and 100 mg/kg, GK significantly (P < 0.001) regulated DexIH after two weeks of treatment compared to the normoglycemic control and hyperglycemic rats. The extract at both doses significantly (P < 0.001) inhibited the spasmolytic activity in both normoglycemic and hyperglycemic rats compared to Imodium®. In rats DexIH rats, only dose 100 mg/kg significantly (P < 0.05) increased laxative effects when compared to the negative control. In vitro antiradical activity of GK revealed vitamin C-like antiradical activity.

Conclusions
This study justifies the traditional use of GK seeds as an antidiabetic.
Professional Identity Formation of Medical Educators
Authors: Mahajan Rajiv , Goyal Parmod Kumar , Singh Tejinder 
Published: July 2022

Context
Process of identity formation in any profession is a unique journey and is influenced by many internal and external factors. The factors which enable the development of professional identity of medical educators have been sparsely studied.

Aim
The aim of this study was to identify the factors which influence the professional identity formation (PIF) of medical educators and the competencies needed to develop such identity, through their self-reflection.

Materials and Methods:
A descriptive exploratory study was designed and executed through self-administered Google Forms having open-ended questions. Themes were generated and concept map was designed.

Results
Internal zeal, mentoring, networking, self-directed learning, supportive workplace environment, and recognition at the workplace were some of the subthemes generated as influencing factors enabling PIF as a medical educator. Some of the competencies reported were subject knowledge, leadership skills, self-directed learning, and ability to carry out educational scholarship projects.

Conclusion
The study elucidates various factors influencing PIF of medical educators, as reflected by medical educators themselves. Institutional policies can be framed accordingly to facilitate the process of PIF of medical educators.
Outcomes of Allograft Medial Patellofemoral Ligament Reconstruction in Children and Adolescents with Hypermobility
Authors: Reddy Gautam , Hayer Prabhnoor Singh , UlIslam Saif , Mehta Nisarg J , Iqbal Hafiz Javaid , Stables Gareth , Barton-Hanson Nicholas G 
Published: July 2022

Introduction
Medial patellofemoral ligament (MPFL) reconstruction is used to treat patellofemoral instability either in isolation or in combination with other procedures. Use of allograft can preserve native tissue in children and can be advantageous in patients with connective tissue disorders, including ligamentous laxity. There is limited evidence regarding functional outcomes of allograft MPFL reconstruction in children and adolescents. This study aimed to assess the short to mid-term results of allograft MPFL reconstruction in children with hypermobility at a tertiary pediatric orthopedic center.

Materials and Methods:
We retrospectively reviewed all children and adolescents who had undergone allograft MPFL reconstruction over 4 years. The primary outcome measure was the validated Kujala score for patellofemoral disorders. The secondary outcome measures included complications such as redislocation of the patella needing revision surgery. Patients with hypermobility were quantified using Beighton criteria. Statistical analysis was performed using Graph Pad Prism (V6).

Results
Between 2012 and 2016, the senior author performed 76 allograft MPFL reconstructions in 57 patients. Nineteen patients had bilateral surgery. The mean age was 14 (7–16) years with a female: male ratio of 3:1. The mean Beighton score was 7. Hypermobility was part of a syndrome in ten patients. The mean follow-up was 3 (1–4) years. Nine patients had trochleoplasty and six patients had tibial tubercle osteotomy, in addition to allograft MPFL reconstruction. These fifteen patients, who had additional procedures, were excluded during the analysis of the outcome measures. The mean Kujala score was 89 (80–100). The overall complication rate was 11% (9/76). These included two patella fractures and seven (9%) patients with recurrent instability needing revision surgery. There was no significant difference in complication rates between syndromic and nonsyndromic patients (P = 0.9).

Conclusion
Our study shows excellent short to mid-term functional outcomes of allograft MPFL reconstruction in children and adolescents with hypermobility.
Pericardial Effusion in Postcoronavirus Disease Patients with Preserved Ejection Fraction of the Left Ventricle and Normal Values of N-Terminal-Pro B-Type Natriuretic Peptide-Link with C-Reactive Protein and D-Dimer
Authors: Begić Edin , Iglica Amer , Gojak Refet , Baljić Rusmir , Begić Zijo , Durak-Nalbantić Azra , Halilčević Mirela , Džubur Alen , Begić Alden , Lepara Orhan , Begić Nedim , Šljivo Armin , Naser Nabil , Stanetic Bojan 
Published: July 2022

Aim
The aim of this study was to link the values of D-dimer and C-reactive protein (CRP), with the occurrence of pericardial effusion in patients who had coronavirus disease 2019 (COVID-19) and have preserved systolic function of the left ventricle (LV).

Methods
This was a prospective study and included 146 patients who underwent echocardiographic examination 30 days after the acute phase of COVID-19. Patients who were placed on mechanical ventilation, patients who had pulmonary thromboembolism or acute coronary syndrome during the acute period of the disease, patients who had an ejection fraction of the LV <50%, patients who were diagnosed with pericarditis during acute illness or clinical signs of heart failure (or had elevated N-terminal-pro hormone B-type natriuretic peptide value), with verified renal or hepatic dysfunction were excluded from the study, including patients with diabetes mellitus Type 1, patients with cancer, connective tissue disease, or pregnant women. The existence of cardiovascular risk factors (hypertension, diabetes mellitus Type 2, and hyperlipidemia), the presence of previous ischemic heart disease, maximum values of D-dimer, and CRP (during the first 15 days of the disease) was taken into the analysis.

Results
Effusion was verified around the right atrium (RA) in 104 patients (3.85 ± 1.75 mm), in 135 patients next to the free wall of the right ventricle (RV) (5.24 ± 2.29 mm), in front of the apex of the LV in 27 patients (2.44 ± 0.97 mm), next to the lateral wall of LV in 35 patients (4.43 ± 3.21 mm), and behind the posterior wall of LV in 30 patients (2.83 ± 1.62 mm). Mean CRP values during the acute phase of the disease were 43.0 mg/L (8.6–76.2 mg/L), whereas D-dimer mean value was 880.00 μg/L (467.00 –2000.00 μg/L). CRP values correlated with effusion next to the free wall of RV (rho = 0.202; P = 0.018). The D dimer correlated with effusion around RA (rho = 0.308; P = 0.0001).

Conclusion
The clinical picture of the post-COVID patients could be explained by the appearance of pericardial effusion. D-dimer value correlates with the occurrence of effusion around RA, whereas CRP value correlates with effusion next to the free wall of RV.
An Immunohistochemical Expression of CK5/6, CK7, and CK20 on Cell Blocks in Metastatic Cervical Lymphadenopathy
Authors: Kaur Amanpreet , Singh Jaspreet , Devgan Rajiv , Utreja Utkarshni 
Published: July 2022

Background
The neck is a common site of both primary and secondary malignancies. Many tumors from the head and neck (oral cavity, larynx, and pharynx), lung, and gastrointestinal tract metastasize to cervical lymph nodes. At most times, tumors are diagnosed by morphology, sometimes it is difficult to diagnose an unknown primary presenting as metastatic lymphadenopathy solely on the basis of morphology. Specific histological cell types can be confirmed by the use of immunohistochemistry.

Aim
The present study evaluated the utility of cell block over fine-needle aspiration cytology (FNAC) and immunohistochemical expression of CK5/6, CK7, and CK20 in metastatic cervical lymphadenopathy.

Methods:
This prospective study design was used on a total of 50 cases. FNAC smears and cell blocks were made in all the cases. All the cell blocks were compared with FNAC findings and further subjected to immunohistochemical (IHC) analysis. The necessary statistical analysis was done.

Results and Conclusion
Our study showed that the combined use of the cell block technique and FNAC was more useful and sensitive in diagnosing the metastatic cervical lymph nodes and the accuracy can be further improved by the use of IHC on the cell blocks. The combined use of CK5/6, CK7, and CK20 in metastatic cervical lymphadenopathy is helpful in diagnosing squamous cell carcinoma and adenocarcinoma with known/unknown primary sites.
Immunohistochemical expression of beta-catenin in hepatoblastoma and its clinical significance
Authors: Archana B. , D'Cruze Lawrence , Nazneen Sarah , Thanka J. , Scott Julius Xavier 
Published: July 2022

Background:
Primary hepatic malignancies account for 0.5-2% of all solid tumours in childhood. Hepatoblastoma, a rare embryonic tumour in the general population, represents the most frequent primary hepatic malignancy in the paediatric age group, with an incidence of one new case per million under 15 years of age, median age at diagnosis being 1 year. Aberrant activation of the Wnt/beta-catenin signalling pathway is likely to result in tumorigenesis of hepatoblastoma. The nuclear and intra-cytoplasmic accumulations of beta-catenin correlate with the likely prognosis of the disease. Nuclear expression of beta catenin is associated with a shorter survival, higher stage, and seen in embryonal/undifferentiated types.

Aim:
To study the expression of beta-catenin in hepatoblastoma by immunohistochemistry and correlate it with the tumour histology and survival outcome.

Materials & Methods:
This is a retrospective study of 11 children over a period of 5 years with the diagnosis of hepatoblastoma. These children underwent partial hepatectomy or liver transplantation at the Department of Paediatric Surgery. The clinical, histological and survival data were collected. Immunohistochemical analysis with beta-catenin was done and analysed.

Results:
Mean birth weight of the children was 2.75kg.63.6% had an epithelial type of histology. Beta catenin expression by IHC was studied in 11 cases and found to be positive in 4 cases. Nuclear positivity was noted in 2/4 cases of embryonal type and Cytoplasmic and membranous positivity was seen in the other 2/4 cases. Normal liver showed a membranous pattern of positivity in one case. Negative staining was seen in 6 out of 11 cases.

Conclusion:
Beta catenin is considered to be an useful tool for assessing the prognosis of patients with hepatoblastoma and its expression is associated with a poor survival outcome. There are no validated biomarkers for prognosis so far. However, larger studies incorporating molecular profiling is warranted to establish prognostic factors for planning effective treatment strategies.
Effects of tyrosine kinase inhibitors for controlling Ph+ clone and additional clonal abnormalities in a chronic myeloid leukemia
Authors: Ganguly Bani Bandana , Mandal Shouvik , Banerjee Debasis , Kadam Nitin N. 
Published: July 2022

Purpose:
The chronic myeloid leukemia (CML) is characterized by the presence of t(9;22)(q34;q11) that results in chimerization of BCR and ABL genes on the rearranged chromosome 22 or Philadelphia chromosome (Ph). Imatinib has been established as the first line of therapy for CML; in case of Imatinib failure or resistance, other second or third generation tyrosine kinase inhibitors (TKIs) are considered. However, acquisition of additional clonal abnormalities (ACAs) interferes in management of CML. We described a complex scenario of cytogenetic remission, relapse, response to TKIs and behavior of ACAs in a case of CML.

Materials and Methods:
Conventional G-banding and FISH cytogenetics, and quantitative PCR studies were conducted in the bone marrow for diagnosis and follow up (FU) of the changes of BCR-ABL gene and ACAs at different time intervals.

Results:
Ph− chromosome disappeared within 6 months of Imatinib therapy, and re-appeared within a year. Subsequent change of TKI to dasatinib eliminated the Ph+ clone, but established an ACA with trisomy 8 (+8). Further change to Nilotinib, eliminated +8 clone, but re-emergence of Ph+ clone occurred with an ACA with monosomy 7 (−7). Reinstate of Dasatinib eliminated Ph+ and −7 clones, but with gradual reappearance of Ph+ and +8 clones. The patient discontinued FU, though participated in a long term examination.

Conclusion:
The complexity of ACAs and Ph+ clones needs frequent monitoring with changes of TKI and technologies.