bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sensitivity and Specificity of Toxic Granules in WBC and Immature to Total Neutrophil Ratio in Diagnosis of Neonatal Sepsis
Authors: Ariful Hoq AKM , Tayab Md Abu , Nasiruzzaman AHM , Begum Masuma , Rahman Md Mizanur 
Published: November 2022

Background: Septicemia is the commonest cause of neonatal mortality and severe morbidity. Positive bacterial blood culture result confirms clinically suspected sepsis but it is too late to start antibiotic. We need a easy, reliable and cost effective test to diagnose sepsis in time.
Objective: To see the relation of toxic granule and immature neutrophil with neonatal sepsis.
Material & Methods: This hospital based, cross-sectional study was conducted on 152 neonate with suspected sepsis admitted in Dhaka Shishu Hospital during January 2013 to April 2014. After enrollment all studied neonate were investigated with complete blood cell count, CRP and Blood culture before starting treatment with antibiotic. Raised immature to total neutrophil ratio >0.2 and toxic granules in neutrophil were correlated with positive blood culture test using x2 test.
Result: Out of 152 studied neonate 61.89% were male, 41.94% premature, 48.85% low weight. Blood culture result was found positive in 7.24% neonate. Leukopenia (WBC<5000/mm3), Neutropenia (Neutrophil <1750/mm3), Immature to total neutrophil ratio (I:T) >0.2 and toxic granules were present significantly in sepsis. The sensitivity and specificity of toxic granules to diagnose neonatal sepsis was correspondingly 91.67% and 75% & that of I: T>0.2 were 90.91% and 66.67%.
Conclusion: Toxic granules and Immature to total neutrophil ratio (I: T) >0.2 can be considered as useful tools in the diagnosis of neonatal sepsis to start antibiotic earlier, especially where there is limited modern investigation facilities.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 141-146
Analysis of Pediatric Rasmussen Encephalitis: Experience from A Tertiary Care Hospital in Bangladesh
Authors: Fatema Kanij , Rahman Md Mizanur , Akhter Shaheen 
Published: November 2022

Background: Rasmussens encephalitis (RE) is rare progressive cerebral inflammatory disease predominantly affecting pediatric population. The key clinical features are seizure and hemiparesis. Seizure is mostly focal with or without epileptia partialis continua (EPC). Diagnosis is established by EEG showing epileptic discharges with focal slowing, focal cortical atrophy in neuroimaging and T cell dominated encephalitis in biopsy or autopsy. This study was done to describe the clinical, laboratory features and treatment of RE in Bangladesh perspective.
Materials & Methods: This study was done in Department of Pediatric Neurology, IPNA, BSMMU, Dhaka, Bangladesh. Four admitted children who were diagnosed as RE from January 2016 to July 2019 were included in this study. Retrospective detail data of the all four patients were collected and analyzed.
Results: The age ranging was 3-12 years, all were male. Cognitive decline, speech disorder, hemiparesis were observed in all the patients. Among them 1 had prodrome of fever. All the patients had seizure, mostly focal onset. Among them 2 had EPC. Treatment was given mainly with immune modulatory drugs (Intravenous methyl prednisolone, IV immunoglobulin, oral steroids) and antiepileptic drugs. On follow up all the patients had consequences in the form of hemiparesis, epilepsy, dysphasia, cognitive disorder etc.
Conclusion: Cognitive decline, speech disorder, focal seizure and hemiparesis were the common presentation. EPC was observed in 50% of cases and consequences on follow up in all cases.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 147-154
Frequency and Risk Factors for Hyperglycemia in Children with Acute Lymphoblastic Leukemia During Induction Chemotherapy
Authors: Ahammed Md Tanvir 
Published: November 2022

Background: Hyperglycemia is a common side effect and it has long been recognized as a consequence of corticosteroids and L-asparaginase, chemotherapeutic agents key to ALL treatment. This study was done to determine the frequency and identify the risk factors for hyperglycemia in paediatric ALL during induction chemotherapy.
Material & Methods: This prospective observational study was done among 87 newly diagnosed ALL cases of 1-18 years of age. After initial work up patient got induction chemotherapy according to UK ALL 2003 (modified) protocol in BSMMU. Anthropometric measurements and CBC, RBS/ 2 hours after glucose/ FBS and corresponding urine sugar was assessed after 2nd, 4th, 6th and 9th dose of Lasparaginase and after completion of induction. Data were analyzed by SPSS 17.0.
Results: Eight patients (9.75%) of the study cohort developed hyperglycemia. Among ³10 years of age 36.8% had hyperglycemia compared to 1.6% of younger children (p<0.001). No gender difference was found. Obese and overweight (p <0.001 in both cases), positive family history of diabetes mellitus using 4 drugs during induction remission phase of chemotherapy were found significant risk factors for hyperglycemia.
Conclusion: In this study frequency of hyperglycemia was 9.75% and frequency of transient hyperglycemia (TH) was 7.3%. Older age, obese or overweight children, positive family history of diabetes mellitus, patient getting regimen B according to UK-ALL 2003 (modified) protocol had shown increase the risk of hyperglycemia.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 155-161
Role of Phenobarbitone Maintenance Therapy in Asphyxiated Neonate with Encephalopathy to Control Seizure- A Randomized Clinical Trial
Authors: Begum Mariam , Saha Dipa , Ahmed Tasnim , Hoque SK Azimul , Mistry Banita , Akter Masuda 
Published: November 2022

Background: Seizures after perinatal asphyxia may worsen brain injury. Phenobarbital (PHB) is commonly prescribed anticonvulsant worldwide to control seizure in asphyxiated neonates. The evidence of the best use of maintenance drugs is limited.
Objective: To assess the effectiveness of phenobarbitone maintenance therapy in asphyxiated neonates with seizure.
Material & Methods: A total of 79 asphyxiated neonates (HIE-II/ III), ³35 weeks were enrolled from January 2019 -January 2020 in this randomized clinical trial where cases were categorized into three groups. Group A received phenobarbitone 4mg/ kg/day twice daily for 6 weeks and Group B received 2mg/kg/day once daily for 2 weeks while Group C didn’t receive any anti-seizure medication after acute management. Clinical and electrophysiological study was done at discharge, one and half month of age. Data were analyzed by SPSS version 20.
Result: Mean age in days was 0.96 ± 1.77 in Group-A, 0.66 ± 1.20 in Group-B and 0.55 ± 1.30 in Group-C. Both Group A and C had seizure in 33.34% and 12.5% in group B at 1½ month. During discharge most of the cases had normal EEG, EEG abnormalities were found in 25% cases in group B, 16.67% in group C and 8.33% in group A. At 1 ½ month, EEG abnormality was found more among group C (33.34%) than group A (25%) and B (25%) which was statistically insignificant.
Conclusion: This study concluded that early discontinuation of phenobarbitone after acute management may not increase the risk of clinical and electrographic seizure in future.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 162-167
Sweet Syndrome: A Rare Skin Disorder in Children
Authors: Rahman Mohammad Masudur , Haque Mujammel , Islam Mohammad Imnul , Uddin Mohammad Jamal , Rahman Shahana Akhter 
Published: November 2022

Sweet syndrome (SS) is a rare dermatosis of unknown etiology. It is characterized by fever, neutrophilia, raised and painful plaques on the skin of the face, neck, limbs, and histologically by dermal infiltration of neutrophils. Here, we present a ten-year-old boy who presented with fever and multiple skin lesions for 15 days. On examination, he was febrile and presented with multiple nodular, tender, erythematous rash on face and limbs. Laboratory findings revealed raised inflammatory markers with neutrophilic leukocytosis, skin biopsy showed hyperkeratosis and neutrophilic infiltration of the dermis. Typical history, laboratory investigations including skin biopsy findings were suggestive of diagnosis of SS. Prolonged fever and characteristics skin lesions in any child should be suspected for this rare syndrome. It should be kept in mind as a differential diagnosis in the day-today clinical practice for effective management of this rare disease.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 172-174
Alternating Hemiplegia of Childhood with ATP1A3 Gene Mutation- A Case Report
Authors: Islam Rumana , Fatema Kanij , Rahman Md Mizanur 
Published: November 2022

Alternating hemiplegia of childhood (AHC) is a rare neurological disorder manifested by transient repeated episodes of alternating hemiplegia associated with other neurological events. Though the exact etiology was largely unknown, recently the pathogenic mutation in the ATP1A3 gene encoding for the alpha3 catalytic subunit of Na+/ K+ATPase was found to be the primary cause of AHC. We present the case of 8.5 year old girl with AHC who had a heterozygous de-novo p.Leu839Pro (c.2516T>C) pathogenic mutation of ATP1A3 gene on chromosome 19q13.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 175-177
Edward’s Syndrome-A Case Report
Authors: Dutta Shanta , Tutul Fariah Arman , Dey Dipika , Akter Feroza , Rahman Ziaur , Ahmed Wazir 
Published: November 2022

Edward’s syndrome is commonly known as the trisomy 18 syndrome. It is a devastating genetic disorder that can be characterized by multiple congenital anomalies. About 50% babies with this syndrome do not survive beyond one week of age and approximately 95% does not survive past the first year of life. The feature of Edward’s Syndrome involves in craniofacial, skeletal, cardiovascular, central nervous system and genitourinary malformations. The mortality rate among infants with trisomy 18 is high as a result of cardiac and renal malformations, feeding difficulty, sepsis and central nervous system defects. Here we report a neonate with Edward’s syndrome.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 178-181
Unnoticed Foreign Body (Metallic Hair Clip) Ingestion in An 18 Month Old Child: A Case Report
Authors: Mazumder Md Wahiduzzaman , Akram Lubana , Hassan Md Nazmul , Musabbir Nadira , Begum Fahmida , Rukunuzzaman Md 
Published: November 2022

Accidental foreign body ingestion is common in the pediatric age group particularly between 6 months and 5 years. Most ingested foreign bodies pass easily through the esophagus, into the stomach, and are expelled from the body without complications. However, endoscopic removal will require only 10% - 20% of cases to avoid complications. We present the endoscopic removal of a metallic hair clip in the duodenum of an 18 month old child that was unnoticed initially and diagnosed incidentally.
BANGLADESH J CHILD HEALTH 2021; VOL 45 (3) : 182-185
Sistem Layanan Desa Ciseeng Berbasis Web dan Android untuk Meningkatkan Pelayanan Desa pada Masyarakat
Authors: Sabiq Ahmad , Suhaeri  , Hayurani Herika , Febriyanto Erik , Abror Ammar 
Published: November 2022

Kantor Desa Ciseeng di kecamatan Ciseeng, Kabupaten Bogor, melayani keperluan warganya berkaitan dengan surat-surat, seperti pelayanan pembuatan surat perizinan, pengantar KTP, dan beberapa layanan yang totalnya hampir 30 jenis. Kendala yang dihadapi oleh warga untuk mengajukan surat melalui pelayanan desa adalah mereka harus meluangkan waktu khusus. Untuk warga yang bekerja di luar wilayah Ciseeng, khususnya di luar Kabupaten Bogor, terpaksa harus cuti bekerja selama satu hari. Pada kegiatan Pengabdian kepada masyarakat ini, penulis membangun aplikasi sistem layanan desa Ciseeng berbasis web dan android. Melalui sistem tersebut, diharapkan warga desa Ciseeng dapat lebih mudah mengakses layanan desa, serta staf kantor Desa Ciseeng dapat lebih mudah dan cepat dalam membuat surat-surat yang diperlukan warga. Beberapa perangkat desa yang mengurus perizinan dan perwakilan masyarakat desa telah mencoba menggunakan sistem yang telah dikembangkan, serta diberikan pelatihan penggunaan Sistem Pelayanan berbasis Web dan Android. Setelah mengikuti pelatihan tersebut, sebagian besar peserta dapat menguasai penggunaan Sistem Layanan Desa yang dikembangkan.
Pendampingan dan sosialisasi Asuhan Mandiri Tanaman Obat Keluarga (Asman Toga) Sebagai Obat Tradisional Pada Masyarakat di Boyolali
Authors: Fitriani Rizky Ainun , Amin Rosa Sayentina , Jannah Nida’ Nur , Novarista Eky Wahyu , Hapsari Ainur Tri , Anggraini Nurul Tri , Arrizky Nur Muhammad , Halwa Husna Amalia , Salsabila Farah , Utama Haya Nabilah , Puteri Alvita Marshanda Purnama , Alkautsar Hamimatusalma , Husna Kharisma Aulia , Damayanti Alida Rahmalia , Rosalinda Jessica , Suhendi Andi , Wahyuni Arifah Sri 
Published: November 2022

Pengembangan kesehatan tradisional di masyarakat dapat dilakukan dengan upaya pembinaan asuhan mandiri pemanfaatan obat tradisional. Kegiatan sosialisasi untuk meningkatkan pemahaman serta pengetahuan masyarakat terkait pemanfaatan Tanaman Obat Keluarga (TOGA) dan tanaman obat herbal penting dilakukan sebagai upaya pengembangan Kesehatan masyarakat. Kegiatan ini dilakukan dengan penyuluhan tentang jenis Tanaman untuk Obat Herbal dan cara pengolahannya. Kegiatan dihadiri oleh ibu-ibu PKK sebagai kelompok antara yang nantinya dapat meneruskan program ini lebih lanjut sampai dengan tingkat keluarga. Untuk menilai keefektifan penyuluhan, maka dilakukan pretes dan postes dengan soal sebanyak 20 pertanyaan. Hasil menunjukkan bahwa sosialisasi yang dilakukan mampu meningkatkan pengetahuan masyarakat tentang pengolahan dan pemanfaatan TOGA dan tanaman herbal. Tersosialisasinya pemanfaatan tanaman sebagai herbal dapat meningkatkan kesejahteraan masyarakat dan berpotensi meningkatkan nilai ekonomi masyarakat.
ANALISIS KINERJA DEVELOPER TERHADAP KEPUASAN PENGHUNI PADA PERUMAHAN DAGYMOI GREEN VILLAGE TERNATE
Authors: Ahadian Edward Rizky , Misbah Zulkarnain K. , S M. Taufiq Yuda 
Published: November 2022

Pertambahan jumlah penduduk di Kota Ternate berbanding lurus dengan meningkatnya kebutuhan terhadap tempat tinggal baik perumahan ataupun non perumahan. Para pelaku bisnis properti seperti developer atau pengembang perumahan perlu memanfaatkan peluang ini secara optimal untuk bersaing merebut pasar. Kebutuhan dan keinginan konsumen atau penghuni harus mampu dipenuhi oleh developer, sehingga penghuni dapat memperoleh kepuasan dari membeli rumah yang ditawarkan. Kinerja dari pengembang perumahan dapat terlihat dari kepuasan konsumen yang akan mempengaruhi tingkat penjualan di masa sekarang maupun yang akan datang. Penelitian ini dilakukan dengan teknik pengumpulan data dengan kuisioner (angket) dengan objek penelitian adalah penghuni Perumahan Dagymoi Green Village Soa Puncak di Kota Ternate. Analisis yang digunakan yaitu metode Customer Satisfaction Index (CSI) dan Importance Performance Analysis (IPA). Hasil perhitungan CSI diperoleh indeks kepuasan penghuni perumahan Dagymoi Green Village Ternate berada pada kategori cukup puas dengan nilai CSI sebesar 63,56%. Pada analisis IPA sebagian besar variabel yaitu 30 variabel yang masuk kategori pertahankan prestasi (keep up the good work), 18 variabel masuk kategori prioritas rendah (low priority) dan 3 variabel yang masuk kategori berlebihan (overkill) yaitu variabel yang dianggap tidak begitu penting dalam pemenuhan penghuni perumahan namun penghuni perumahan menerima lebih dari yang diharapkan atau pelaksanaannya sangat baik sehingga tidak menjadi prioritas.
Abnormal regional homogeneity and amplitude of low frequency fluctuation in chronic kidney patients with and without dialysis
Authors: Yu Huan , Zhang Chaoyang , Cai Yan , Wu Ning , Duan Kai , Bo Wenwei , Liu Ying , Xu Zitong 
Published: November 2022

PurposeThe study characterizes regional homogeneity (ReHo) and amplitude of low frequency fluctuations (ALFF) in abnormal regions of brain in patients of chronic kidney disease (CKD).Materials and methodsA total of 64 patients of CKD were divided into 26 cases of non-dialysis-dependent chronic kidney disease (NDD-CKD), and 38 cases of dialysis-dependent chronic kidney disease (DD-CKD). A total of 43 healthy controls (normal control, NC) were also included. All subjects underwent resting-state functional magnetic resonance imaging (rs-fMRI). ALFF and ReHo data was processed for monitoring the differences in spontaneous brain activity between the three groups. ALFF and ReHo values of extracted differential brain regions were correlated to the clinical data and cognitive scores of CKD patients.ResultsNon-dialysis-dependent group has increased ALFF levels in 13 brain regions while that of DD group in 28 brain regions as compared with NC group. ReHo values are altered in six brain regions of DD group. ALFF is correlated with urea nitrogen and ReHo with urea nitrogen and creatinine. DD group has altered ReHo in two brain regions compared with NDD group. The differences are located in basal ganglia, cerebellar, and hippocampus regions.ConclusionAbnormal activity in basal ganglia, cerebellar, and hippocampal regions may be involved in the cognitive decline of CKD patients. This link can provide theoretical basis for understanding the cognitive decline.
Cataguases na literatura e no cinema
Authors: Silva Lucas Neiva da , Mendes Marco Aurélio de Sousa 
Published: November 2022

Este trabalho apresenta o relato da aplicação de uma proposta de intervenção, cujo objetivo é a promoção do letramento literário e a ampliação de repertório de uma turma de nono ano do ensino fundamental. A hipótese inicial era de que o reconhecimento dos espaços físicos da cidade de Cataguases presentes no conto Amigos e no romance Estive em Lisboa e lembrei de você, ambos do autor Luiz Ruffato, e nas suas respectivas adaptações para o cinema pudesse motivar os alunos. Tal hipótese foi confirmada após a análise dos resultados. Para a confluência entre a teoria e prática, foi adotada a orientação metodológica da pesquisa-ação, conforme Thiollent (1986). Os principais aportes teóricos foram: Candido (2011); Cosson (2016, 2018; Paulino, Cosson (2009); Iser, (1996); Abdala Junior (1995); Hutcheon (2013).
Turkish Newspapers Wildfire Coverage During the Summer of 2021
Authors: BAYKAL FİDE Ece 
Published: November 2022

In this article, some of the assumptions commonly put forward in media research about wildfires and disasters will be examined by
exploring how the 2021 fires in Turkey were framed in newspapers with differing editorial and political views. Within the scope of this
reporting, the discussion will centre on how these reports of fires, omitted any mention of climate change and its impact on these disasters.
Media organizations evaluate disasters through the lens of their geographical and national positions as well as power relations, without
associating them with global events such as climate change. The media in Turkey covered the fires within the framework of their current
political and social conflicts. This situation has seen newspapers deliver news focused on extinguishing fires, post-disaster response
discussions and 'last minute' developments, instead of offering solutions on climate change and the implementation of mitigation or
adaptation policies. In this research, through the use of frame analysis method, the approaches and the actors that newspapers represented
while covering wildfires are analyzed. In the next phase, news frames are studied whether they are oriented to reveal the causes of the
wildfires (diagnostic) or to propose solutions (prognostic) regarding firefighting or climate adaptation policies. The publication which
provides most solutions, referred to solutions in 14,2% of all its news. Regardless of their political views all newspapers in the sample
generally proposed solutions regarding the recovery process rather than proactive or preventative climate adaptation policies.
Faktor Risiko COVID-19 pada Anak
Authors: Pangow Debora K. , Rampengan Novie H. , Wilar Rocky 
Published: November 2022

Abstract: The prevalence of COVID-19 cases is still increasing in children, as well as the morbidity and mortality rates. Therefore, it is necessary to understand the risk factors involved in the incidence of COVID-19 infection in children. This study aimed to identify and analyze the risk factors for the transmission of COVID-19 in children. This was a literature review study using four databases namely Scopus, ProQuest, Pubmed, and Science Direct. The results obtained 16 literatures about the risk factors for COVID-19 in children with the basic concept of the epidemiological triad of COVID-19 risk factors, namely the host, agent, and environment. The literatures indicated that the host risk factors were gender, vitamin D deficiency, age, asthma comorbid or underlying medical conditions, and race. The agent risk factors were the emergence of the delta virus variant, meanwhile the environmental risk factors were the exposure to viruses in the household or family cluster, exposure to endemic areas, exposure to bus travel, virus transmission at school, and close contact with people diagnosed with COVID-19. In conclusion, risk factors for COVID-19 in children with interaction of transmission factors of COVID-19 which are host, agent, and environment cause the rapid development of new coronavirus cases. Most transmission of COVID-19 in children is derived from family contact (environment).Keywords: risk factors for COVID -19; transmission in children Abstrak: Prevalensi kasus COVID-19 terus meningkat pada anak, demikian pula angka kesakitan maupun angka kematian. Oleh karena itu faktor risiko yang terlibat kejadian infeksi COVID-19 pada anak perlu dipahami secara detil. Penelitian ini bertujuan untuk mengidentifikasi dan menganalisis faktor risiko penularan COVID-19 pada anak. Jenis penelitian ialah suatu literature review yang menggunakan empat pengkajian database yaitu Scopus, ProQuest, Pubmed, dan ScienceDirect. Hasil penelitian mendapatkan 16 literatur yang meneliti faktor risiko COVID-19 pada anak, dengan konsep dasar trias epidemiologi faktor risiko COVID-19 yaitu pejamu, agen, dan lingkungan. Faktor-faktor risiko pejamu yaitu jenis kelamin, defisiensi vitamin D, usia, dan komorbiditas asma atau kondisi medis yang mendasari, dan ras. Faktor risiko agen yaitu muncul-nya varian virus delta, sedangkan faktor lingkungan yaitu paparan virus dalam rumah tangga atau klaster keluarga, paparan daerah endemik, paparan perjalanan bus, penularan virus disekolah dan kontak dekat dengan orang terdiagnosis COVID-19. Simpulan penelitian ini ialah faktor-faktor risiko kejadian infeksi COVID-19 pada anak dengan interaksi faktor penularan COVID-19 yaitu faktor pejamu, agen dan lingkungan, mengakibatkan perkembangan kasus coronavirus baru yang sangat cepat. Penularan pada anak terbanyak berasal dari riwayat kontak keluarga (lingkungan).Kata kunci: faktor risiko COVID-19; penularan pada anak