bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of novel susceptibility factors related to CP/CPPS‐like symptoms: Evidence from a multicenter case‐control study
Authors: Zhang Meng , Jin Chen , Kong Xiangbin , Meng Jialin , Fan Song , Ding Yang , Fang Qiaozhou , Dong Ting , Zhang Houliang , Ni Jinliang , Liu Yi , Wang Hua , Chen Xianguo , Hao Zongyao , Peng Bo , Zhang Li , Wang Zhiping , Liang Chaozhao 
Published: February 2022

AbstractBackgroundWe aimed to systematically identify novel susceptible factors related to the occurrence and development of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)‐like symptoms that were not limited to lifestyles or dietary habits in Chinese population.MethodsWe recruited participants from three centers (Shanghai [northeast], Hefei [east], and Lanzhou [northwest]) from August 2020 to June 2021. Demographics, lifestyles, dietary habits, past medical history, and national institutes of health‐chronic prostatitis symptom index (NIH‐CPSI) were collected from the individuals via optimized questionnaires. Logistic regression analysis and multivariate adjustment models were used to calculate the odds ratio (OR) and 95% confidence interval (95% CI) to assess the association between these variables and CP/CPPS‐like symptoms.ResultsA total of 1851 participants were enrolled in this study (764 cases and 1087 controls). Age distributions differed between groups (median, range: 32, 18–74 vs. 29, 18–70, p < 0.001). After adjustment, physicochemical occupational hazards were identified significantly related to CP/CPPS‐like symptom occurrence and development (ORoccurrence: 1.389, 95% CI: 1.031–1.870, p < 0.001; ORdevelopment: 2.222, 95% CI: 1.464–3.372, p < 0.001); besides, greater than or equal to four ejaculations per week significantly increased the likelihood of CP/CPPS‐like symptoms compared with one ejaculation per week (ORoccurrence: 3.051, 95% CI: 1.598–5.827, p = 0.001). For these patients, who were easily felt gastrointestinal discomfort caused by spicy food intake, they had a higher incidence to affect with CP/CPPS‐like symptoms (ORoccurrence: 2.258, 95% CI: 1.858–2.745, p < 0.001). In addition, history of drug allergy and genitourinary infections were identified as independent susceptible factors for the occurrence of CP/CPPS‐like symptoms (ORoccurrence: 1.689, 95% CI: 1.007–2.834, p = 0.047; ORoccurrence: 3.442, 95% CI: 2.202–5.382, p < 0.001, respectively), while the history of rheumatic immune diseases was found tightly associated with the development of CP/CPPS‐like symptoms (ORdevelopment: 2.002, 95% CI: 1.008–4.058, p = 0.048).ConclusionInfection/inflammatory/immune‐related disorders, novel dietary habits, and lifestyles associated with the susceptibility of CP/CPPS‐like symptoms' occurrence and development are identified. Altering these irregular conditions serves as potential strategies for the treatment of patients with CP/CPPS‐like symptoms.
Mechanisms of influence of the Semi‐Annual Oscillation on stratospheric sudden warmings
Authors: Gray Lesley J. , Lu Hua , Brown Matthew J. , Knight Jeff R. , Andrews Martin B. 
Published: February 2022

AbstractThe influence of the Semi‐Annual Oscillation (SAO) on the timing and evolution of major sudden stratospheric warmings (SSWs) is examined using the 2008/2009 SSW as the primary case‐study. When the zonal winds in both the troposphere and the SAO region of the equatorial upper stratosphere/lower mesosphere are relaxed towards reanalysis fields in the UK Met Office Unified Model, a remarkably accurate representation of the January 2009 SSW is achieved. The accurate timing of the SSW is determined by the SAO zonal wind relaxation. The westerly‐to‐easterly phase transition of the SAO in the lower mesosphere (0.1–0.5 hPa) is found to be a key factor for this influence. It defines an initial conical‐shaped vortex that determines the upward propagation of wave activity and subsequent evolution of wave mean‐flow interaction. Internal transient wave reflection in the subtropics and associated wave‐induced acceleration of the mean‐flow is found to be an important component, strengthening the vortex and thus delaying the onset of the SSW. The sensitivity of SSW timing to the equatorial westerly winds in the lower mesosphere is further explored in the context of all major SSWs during the 1979–2018 period. The timing of SSWs is found to be significantly correlated with the timing of the equinoctial westerly‐to‐easterly phase transition at 0.3 hPa in early winter (r = 0.79). This relationship is discussed in the context of the more widely recognised influence of the quasi‐biennial oscillation (QBO). These results suggest that accurate simulation of the timing of SAO phase transitions, as well as knowledge of the QBO phase, is likely to provide additional and extended Northern Hemisphere wintertime seasonal forecast skill.
What makes a good educational research summary? A comparative judgement study of mathematics teachers' and mathematics education researchers' views
Authors: Rycroft‐Smith Lucy , Stylianides Andreas J. 
Published: February 2022

AbstractThe field of knowledge brokering in education—aiming to better connect research to practice—is currently emerging. Evidence of a community dissonance between researchers and practitioners in education suggests that models of knowledge brokering that consider the perspectives and priorities of both groups are required. It is also a priority to identify what kinds of knowledge brokering products such as research summaries are successful at communicating research to teachers, potentially functioning as boundary objects. We report findings from a comparative judgement study where a group of 28 mathematics teachers and a group of 19 mathematics education researchers ranked twenty research summaries, from different sources, in terms of their success at communicating the research to teachers, and explained which features contributed to this ranking. Overall the findings suggest moderate consensus both within and between the two groups, and some important areas of difference. Both groups agreed that graphic design was the most important element of a research summary; that being summarised, having implications for practice and being easy to read or accessible and well‐structured were key features of a research summary; and that the length of the research summary or the time it might take to read were also important. Whereas teachers mentioned the choice of topic of the research summary and to some extent language more than researchers, researchers highlighted some other features of successful research summaries for them that teachers did not: ideas around methodology and use of evidence, opportunities for critical reflection, and issues of trust and credibility.
An Efficient, Multi‐element AC/TiO2/WO3 Photocatalyst for the Degradation of Tetracycline Hydrochloride
Authors: Xu Mengdi , Nan Hui , Yang Hao , Xue Caihong , Fu Hua , Yang Guijun , Chen Huiyuan , Lin Hong 
Published: February 2022

AbstractIn this study, a simple one‐step hydrothermal synthesis of three‐element complex system photocatalyst technology is systematically studied. The results show that due to the complex heterojunction formed by titanium dioxide (TiO2), tungsten trioxide (WO3) and activated carbon (AC) and the strong adsorption performance of AC, the catalytic efficiency and cycle stability of the composite have been significantly improved. The excellent electron transport ability of AC is conducive to the separation of carriers, so that the electron transfer between AC/TiO2 and AC/WO3 can make it achieve a heterojunction effect similar to TiO2/WO3. The rich specific surface area of AC and the pores of the “labyrinth” structure can provide a higher concentration of degradable substances inside the catalyst, and the degraded substances are quickly transferred to the active site for degradation. Therefore, by controlling the mass ratio of AC/TiO2/WO3, a photocatalyst with high catalytic efficiency and strong cycle stability was successfully prepared (the degradation efficiency is above 95 %, and the degradation efficiency after 5 cycles is above 80 %).
Spirulina Biomass‐Loaded Thermoplastic Polyurethane/Polycaprolacton (TPU/PCL) Nanofibrous Mats: Fabrication, Characterization, and Antibacterial Activity as Potential Wound Healing
Authors: Parın Fatma Nur , Parın Uğur 
Published: February 2022

AbstractThe development of antibacterial products with therapeutic properties has become a popular human health trend. Herein, for the first time, we described an effective antibacterial thermoplastic polyurethane/polycaprolacton (TPU/PCL) composite nanofibers loaded with the spirulina biomass by electrospinning method for wound care applications. The chemical, microstructural, mechanical, wettability properties and antibacterial activities of produced electrospun TPU/PCL/spirulina fibers with varied spirulina concentrations (1, 3, and 5 %, w/v to polymer solution) were investigated by Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FT‐IR), UV‐VIS Spectroscopy, optical tensiometer and tensile testing machine. The SEM micrographs revealed that all resultant fibers have an average fiber diameter of 228–312 nm and a significant porosity (86‐90 %). FT‐IR spectrum pointed out no chemical bonding between spirulina and polymer matrixes. Increasing the spirulina content caused an increased swelling capacity of the nanofibers. Furthermore, TPU/PCL/spirulina samples indicated superhydrophilic property with contact angle values almost 36°, 0°, and 0°, respectively. The resultant TPU/PCL/spirulina fibers, released 36.89 ppm, 59.4 ppm, and 209.1 ppm of the spirulina after 8 hours, respectively and showing the effect of interactions between the TPU/PCL matrix and the spirulina on its release of the TPU/PCL matrix. Fluid absorption value have increased as incorporation of spirulina into the polymer matrix. All TPU/PCL/spirulina fibers and spirulina have antibacterial efficiency against E.colibacteria.TPU/PCL nanofiber with the highest amount of spirulina (5 %) has the highest tensile strength with 3.89±0.19 MPa.The electrospun TPU/PCL/spirulina nanofibers appear to be a potential candidate material for tissue engineering and wound care applications, based on our results.
Bimetallic Multi‐Level Layered Co‐NiOOH/Ni3S2@NF Nanosheet for Hydrogen Evolution Reaction in Alkaline Medium
Authors: Wu Zhong , Feng Yanhui , Qin Zhenbo , Han Xiaopeng , Zheng Xuerong , Deng Yida , Hu Wenbin 
Published: February 2022

AbstractDevelopment of efficient non‐noble metal catalysts for water splitting is of great significance but challenging due to the sluggish kinetics of the hydrogen evolution reaction (HER) in alkaline medium. Herein, a bimetallic multi‐level layered catalytic electrode composed of Ni3S2 nanosheets with secondary Co‐NiOOH layer of 3D porous and free‐standing cathode in alkaline medium is reported. This integrated synergistic catalytic electrode exhibits excellent HER electrocatalytic performance. The resultant Ni0.67Co0.33/Ni3S2@NF electrode displays the highest HER activity with only overpotentials of 87 and 203 mV to afford current densities of 10 and 100 mA·cm−2, respectively, and its Tafel slope is 80 mV·dec−1. The chronopotentiometry operated at high current density of 50 mA·cm−2 shows negligible deterioration, indicating better stability of Ni0.67Co0.33/Ni3S2@NF electrode than Pt/C (20 wt.%). Such a desirable catalytic performance is attributed to the modification of physical and electronic structure that exposes abundant active sites and improves the intrinsic catalytic activity toward HER, which is also confirmed by electrochemically active surface area and X‐ray photoelectron spectroscopy analysis. This work provides a strong support for the rational design of high‐performance bimetallic electrodes for industrial water splitting.
Incorporation of the DEMATEL into evaluations of CSR performance in BOT projects
Authors: Hu Yi‐Chung , Chiu Yu‐Jing , Yen Ghi‐Feng , Ken Yen‐Wei 
Published: February 2022

AbstractBuild–operate–transfer (BOT) is a public–private partnership (PPP) model in which the government commissions private enterprises to develop large‐scale public infrastructure. Owing to the large scale and long duration of BOT projects, BOT companies have diverse stakeholders and assume more social responsibility than ordinary companies do. Although studies on corporate social responsibility (CSR) are plentiful, most of them have examined CSR from the perspective of consumers or private‐ or state‐owned enterprises. Few studies have investigated BOT and CSR from a holistic perspective. Therefore, we adopted systems thinking to examine multistakeholder and multicriteria scenarios for investigating the CSR of BOT companies. This study established a research framework through the Delphi method. Subsequently, the decision‐making trial and evaluation laboratory and an analytic network process were used to identify causality among these criteria. Finally, the results are discussed from a systemic perspective, and suggestions for future strategies are provided.
Azide‐Modified Nucleosides as Versatile Tools for Bioorthogonal Labeling and Functionalization
Authors: Müggenburg Frederik , Müller Sabine 
Published: February 2022

AbstractAzide‐modified nucleosides are important building blocks for RNA and DNA functionalization by click chemistry based on azide‐alkyne cycloaddition. This has put demand on synthetic chemistry to develop approaches for the preparation of azide‐modified nucleoside derivatives. We review here the available methods for the synthesis of various nucleosides decorated with azido groups at the sugar residue or nucleobase, their incorporation into oligonucleotides and cellular RNAs, and their application in azide‐alkyne cycloadditions for labelling and functionalization.
Context, Communities, and Conflict: Novice Language Teachers in Malaysia
Authors: Macalister John 
Published: February 2022

AbstractThis narrative inquiry focuses on two Malaysian novice English language teachers whose pre‐service teacher education had included two years of study abroad. The experiences of novice language teachers remain an under‐investigated area and this study furthers our understanding of that experience. Furthermore, while research on the effectiveness of pre‐service language teacher education has reported mixed results, accounts on the impact of studying abroad claim multiple benefits. Thus this study extends the literature on novice language teachers by adding a study abroad dimension. It asks what influences the teachers’ pedagogical decision‐making and how they now view their study abroad. In line with models of language teacher cognition, a dynamic interplay of influences on these novice teachers’ classroom practice emerges. These influences include their ‘apprenticeship of observation’, the national and local context, their professional learning, and support networks. Multiple layers of both context and community were found to influence the teachers. The study abroad experiences features in both positive and negative ways. It conveys status, and raises expectations, but is not always regarded as relevant to teaching in Malaysian primary schools. It can also, however, have an alienating effect. This is a previously unacknowledged effect of study abroad on language teachers.
Interactions between polymeric nanoparticles and different buffers as investigated by zeta potential measurements and molecular dynamics simulations
Authors: Inam Wali , Bhadane Rajendra , Akpolat Rukiye Nur , Taiseer Rifahul Abrar , Filippov Sergey K. , Salo‐Ahen Outi M. H. , Rosenholm Jessica M , Zhang Hongbo 
Published: February 2022

AbstractZeta potential is an essential surface parameter in the characterization of nanoparticles, determined at the interface of loosely bound ions (diffuse layer) at the nanoparticle surface and free ions in solution. The ionic concentration and pH of the solution are known to, by definition, influence the composition of the diffuse layer and zeta potential accordingly. Thus, to fix the solution's pH for valid zeta potential measurements, buffers are frequently used. However, an issue that remains largely neglected is that buffers could also additionally alter the electrokinetic properties of nanoparticles through specific molecular interactions. Therefore, a thorough molecular understanding of buffer–nanoparticle interactions is needed to correctly implement zeta potential results. Thus, in order to study nanoparticle–buffer interactions, we first adopted a simple experimental approach of measuring zeta potential of common polymeric nanoparticle systems at different buffer concentrations, pH, and nanoparticle–buffer fraction ratios. We observed that zwitterionic/cationic buffer molecules impart significant interference to the electrokinetic properties of structurally diverse polymer nanoparticles, by causing zeta potential suppression or even inversion during the experiments. In parallel, advancement in computation resources nowadays allow studying intermolecular interactions of nanoparticles and other complex molecules by molecular dynamics (MD) simulations. Thus, by performing MD simulations for six different polymeric nanomaterials with commonly used buffer molecules, we found that noncovalent interactions play a significant role in altering the observed zeta potential values, which may contribute to erroneous results and false particle characterizations if not taken properly into account in zeta potential measurements.
WikiPathways: Integrating Pathway Knowledge with Clinical Data
Authors: Slenter Denise N. , Kutmon Martina , Willighagen Egon L. 
Published: February 2022

SummaryThroughout the chapters in this book, pathways are used to visualize how genetically inheritable metabolic disorders are related. These pathways provide common conceptual models which explain groups of chemical reactions within their biological context. Visual representations of the reactions in biological pathway diagrams provide intuitive ways to study the complex metabolic processes. In order to link (clinical) data to these pathways, they have to be understood by computers. Understanding how to move from a regular pathway drawing to its machine-readable counterpart is pertinent for creating proper models. This chapter outlines the various aspects of the digital counterparts of the pathway diagrams in this book, connecting them to databases and using them in data integration and analysis. This is followed by three examples of bioinformatics applications including a pathway enrichment analysis, a biological network extension, and a final example that integrates pathways with clinical biomarker data.
Procedure using CAD/CAM-manufactured insertion guides for purely mini-implant-borne rapid maxillary expanders
Authors: Wilmes Benedict , Tarraf Nour Eldin , de Gabriele Renzo , Dallatana Gianluca , Drescher Dieter 
Published: February 2022

AbstractWith traditional rapid palatal expansion (RPE), orthopaedic forces are transmitted to the skeletal structures via the anchor teeth potentially leading to several unwanted dental side effects. To prevent these issues, tooth–bone-borne or purely bone-borne expanders were introduced using mini-implants in the palate. In this paper, the digitally planned Quadexpander is described which permits palatal expansion with only skeletal anchorage. The use of virtual insertion planning allows for insertion in areas of ideal bone, while avoiding roots and vital structures as well as the possibility of insertion into sites which would otherwise not be considered usable. A second advantage of digital planning is that mini-implants and the expander can be inserted in just one appointment.
Laser polishing: a review of a constantly growing technology in the surface finishing of components made by additive manufacturing
Authors: Gisario Annamaria , Barletta Massimiliano , Veniali Francesco 
Published: February 2022

AbstractAdditive manufacturing is a vanguard production technology that has contributed greatly to speed up replacing on the market of complex-shaped components. A delicate and unavoidable phase of additive technology is that relating to the post-processing of the components, especially the finishing process. Post-processing needs to be automated and made scalable so that the technology can actually be adopted also for mass production. In this respect, an emerging post-processing technology suitable for surface finishing, not in contact and easily automatable, is the one that involves the use of laser sources, known by the name of laser polishing. Laser polishing is spreading, in fact, more and more strongly, in the field of manufacturing as a valid alternative to conventional technologies for the surface finishing of metallic components obtained by additive processes. Laser polishing is widely considered very suitable to improving the surface finish of metal components. When compared with the conventional finishing technologies, laser polishing has many benefits in terms of costs and process times especially if automated, through the use of CNC systems and scanning heads. In this manuscript, the knowledge of this technology is deepened through a review of the relevant literature that highlights the aspects of the interaction of the laser beam with the metal alloys most frequently used in 3D printing, without neglecting the importance of the thermo-mechanical properties that derive from it. The analysis conducted on the technology of laser polishing aims therefore at evaluating the potential applications in industrial engineering, mainly with regard to the surfaces quality achievable as a result of the polishing of metal components fabricated by additive manufacturing.
Laser transmission welding of aluminum film coated with heat sealable co-polyester resin with polypropylene films for applications in food and drug packaging
Authors: Gisario Annamaria , Aversa Clizia , Barletta Massimiliano , Natali Stefano , Veniali Francesco 
Published: February 2022

AbstractThe present work deals with the high-power diode laser joining process of aluminum films coated with a polyester resin with polypropylene (PP) films. The first part of the work focused on analyzing the coating process of aluminum films with a polyester resin, using an automatic applicator. The second part of the work was focused on the analysis of the laser joining process of coated aluminum films with plastic counterparts made of PP. Different thicknesses and colors of the PP parts were tested in order to analyze the joining process under a wide range of different conditions. The experimental plan involved the study of the influence of the laser joining parameters, in particular the scanning speed and beam power, on the joints. The joints between aluminum and PP films were subsequently tested by means of tensile and peel-off tests. All the joints between aluminum and PP are obtained through the so-called laser transmission welding (LTW) mechanism. Analysis of the mechanical response of the welded joints allowed to identify the optimal processing window, that is, the choice of the operational parameters that leads to satisfactory welded joints, stating the high potential of laser systems in the joining process of aluminum and PP films for food packaging applications.
Conformal Nets V: Dualizability
Authors: Bartels Arthur , Douglas Christopher L. , Henriques André 
Published: February 2022

AbstractWe prove that finite-index conformal nets are fully dualizable objects in the 3-category of conformal nets. Therefore, assuming the cobordism hypothesis applies, there exists a local framed topological field theory whose value on the point is any finite-index conformal net. Along the way, we prove a Peter–Weyl theorem for defects between conformal nets, namely that the annular sector of a finite defect is the sum of every sector tensored with its dual.