bluuebunny/crossref_metadata_2025_split huggingface dataset:
Training Load Monitoring Practices Used by Strength and Conditioning Coaches in Hurling, Gaelic Football, Camogie, and Ladies Gaelic Football
Authors: Rahilly Declan O , Whelan Niamh , Moane Siobhan 
Published: December 2022

Background: No research has investigated the training load (TL) monitoring practices currently used by strength and conditioning (S&C) coaches in Gaelic games. The purpose of this study was to investigate the TL monitoring practices used by S&C coaches across senior intercounty male and female Gaelic game sports. Study Design: Cross-sectional. Hypotheses: It was hypothesized that (1) TL is commonly monitored, (2) various methods are used by S&C coaches to monitor TL, and (3) the level of qualifications of the S&C coach is of a professional standard. Level of Evidence: Level 4. Methods: A total of 33 (n = 32 male and n = 1 female) S&C coaches participated in the study by completing an online questionnaire that investigated coach biography, coach education, team biography, monitoring practices, rating of perceived exertion, acute:chronic workload ratio, and data implementation. Results: The results showed that S&C coaches had varying levels of experience and education. All 33 coaches (100%) stated they monitored the TL of the players. The most common method used to monitor TL was session rating of perceived exertion, which was used by 91% of coaches. Analysis of an open-ended question afforded each participant the opportunity to share additional information, highlighting 3 themes: (1) communication with players, (2) performance testing, and (3) clarity and support among other coaching staff. Conclusion: Multiple methods are used to monitor TL in Gaelic games. Despite multiple forms of technology available, communication with players provides essential information regarding an athlete’s state. Clinical Relevance: As this is the first study to explore TL monitoring practices used by S&C coaches in Gaelic games, the results may inform the development of educational resources for the guidance of coaches working in Gaelic games in best practice TL monitoring.
Medial Patellofemoral Ligament Reconstruction
Authors: Keeling Laura E. , Curley Andrew J. , Kaarre Janina , Joly Jeannette M. , West Robin V. 
Published: December 2022

Background: Recurrentlateral patellar dislocation is a devastating condition associated with different pathologies, including medial patellofemoral ligament (MPFL) injury, increased tibial tubercle to trochlear groove (TT-TG) distance, and trochlear dysplasia. This video aims to provide an overview of isolated MPFL reconstruction in a patient with recurrent patellar dislocation and chronic MPFL injury. Indications: Isolated MPFL reconstruction is indicated for patients with recurrent lateral patellar instability following an initial trial of nonoperative management, in the absence of other contributing anatomic factors. Candidates for isolated MPFL reconstruction should have a TT-TG distance of <20 mm, and normal or Dejour type A trochlear morphology. Technique Description: Semitendinosus allograft is used to reconstruct the torn or attenuated MPFL. Following diagnostic arthroscopy, an incision is made over the medial border of the patella and dissection is carried through the skin and subcutaneous tissue to the fascia. Two K-wires are over-drilled and two 3.5-mm Arthrex SwiveLock anchors are placed. The allograft is prepared and whipstitched on both sides. The central portion of the graft is tide down to the anchors. A second incision is then made on the medial side of the knee over the epicondyle. Dissection is carried down to the fascia, and palpation is used to identify Schottles’ point. This is confirmed with fluoroscopy. An 8-mm drill bit is then used to drill to a depth of 60 mm on the femoral side. The grafts are passed one at a time through the femoral tunnel. The femoral side is fixed with an Arthrex BioComposite Interference Screw and the incisions are subsequently irrigated and closed in a layered fashion. Results: MPFL reconstruction demonstrates good functional and clinical outcomes with high rates of patient satisfaction and low rates of failure. A recent systematic review demonstrated an 84% rate of return to sport, improved postoperative outcomes, and pooled risks of recurrent instability and reoperation of less than 5% following isolated MPFL reconstruction. Conclusion: Isolated MPFL reconstruction should be considered for patients with recurrent patellar instability in the absence of other clinical risk factors. The author(s) attests that consent has been obtained from any patient(s) appearing in this publication. If the individual may be identifiable, the author(s) has included a statement of release or other written form of approval from the patient(s) with this submission for publication.
External validation of the PEGeD diagnostic algorithm for suspected pulmonary embolism in an independent cohort
Authors: Robert-Ebadi Helia , Roy Pierre-Marie , Sanchez Olivier , Verschuren Frank , Le Gal Grégoire , Righini Marc 
Published: December 2022

Abstract
Sequential diagnostic algorithms are used in the case of suspected pulmonary embolism (PE). The PEGeD study proposed a new diagnostic strategy to reduce the use of computed tomography pulmonary angiography (CTPA). We aimed to externally validate this diagnostic strategy in an independent cohort. We analyzed data from 3 prospective studies of outpatients with suspected PE. As per the PEGeD algorithm, patients were classified as having a low, moderate, or high clinical pretest probability (C-PTP). PE was excluded with a D-dimer &lt;1000 ng/mL in case of low C-PTP and &lt;500 ng/mL in case of moderate C-PTP. We assessed the yield and safety of this approach and compared them with those of previously validated algorithms. Among the 3308 evaluated patients, 1615 (49%) patients could have had PE excluded according to the PEGeD algorithm, without the need for imaging. Of these patients, 38 (2.3%; 95% confidence interval [CI], 1.7-3.2) were diagnosed with a symptomatic PE at initial testing or during the 3-month follow-up. On further analysis, 36 patients out of these 38 patients had a positive age-adjusted D-dimer. The risk of venous thromboembolic events among the 414 patients with a D-dimer &lt;1000 ng/mL but above the age-adjusted D-dimer cut-off was 36 of 414 (8.7%; 95% CI, 6.4-11.8). We provide external validation of the PEGeD algorithm in an independent cohort. Compared with standard algorithms, the PEGeD decreased the number of CTPA examinations. However, caution is required in patients with a low C-PTP and a D-dimer &lt;1000 ng/mL but above their age-adjusted D-dimer cut-off.
Identification of the wood species in the wooden sheath of Indonesian kris by synchrotron X-ray microtomography
Authors: Cipta Hairi , Nugroho Widyanto Dwi , Tazuru Suyako , Sugiyama Junji 
Published: December 2022

AbstractA kris is a traditional dagger that originated in Indonesia. A kris is distinguished by its asymmetrical blade, which has layers of different metals bonded on its surface. Wood is the main material used to make the kris sheath. To preserve the knowledge about wood selection of the sheath, wood identification is a crucial first step. In the present study, we identified the wood species used to make the kris sheath. We performed synchrotron X-ray microtomography, which allows microscopic observation with minimum sample availability. Seven wooden kris sheaths were investigated. The results showed that synchrotron X-ray microtomography is suitable for observing the important microscopic anatomical features of the wood species in kris sheaths. We found that Dysoxylum spp., Tamarindus indica, and Kleinhovia hospita were used as sheath materials. We also visualized the spatial distribution of the prismatic crystals inside the T. indica and K. hospita xylem cells. Abundant crystals were present in T. indica arranged in longitudinal alignment inside the chambered axial parenchyma cells. The crystals were arranged in radial alignment inside the ray cells of K. hospita. The existence of abundant crystals in series may be important for the mechanical support of certain xylem cells.
Response to commentary article on environmental quality standards for diclofenac derived under the European water framework directive: 1. Aquatic organisms, by Maack et al. 2022
Authors: Leverett Dean , Merrington Graham , Crane Mark , Wilson Iain 
Published: December 2022

AbstractIn this short article, we respond to a Commentary by Maack et al. (Environ Sci Eur 34:24, 2022) in which they challenge recommendations in Leverett et al. (Environ Sci Eur 33:133, 2021) for setting an aquatic Environmental Quality Standard (EQS) for the pharmaceutical diclofenac. Maack et al. recommend the use of results from a stream mesocosm study as the main point of departure for setting the EQS and dismiss the use of a Species Sensitivity Distribution (SSD) containing relevant and reliable single species data because of bimodality in this distribution. We present the key mesocosm data used by Maack et al. and note that these are highly variable, include control mortalities of up to 60%, and, as reported by the original authors, show a significant effect only at the highest test concentration and not at the estimated value proposed by Maack et al. We also show that there are neither regulatory nor technical grounds for dismissing the use of an SSD and respond to minor criticisms of our compliance assessment (comparison of different EQS values with reported concentrations in European surface waters). Finally, we provide comment on the EQS derivation process and subsequent opinion of the diclofenac EQS dossier by the European Commission’s Scientific Committee on Health, Environmental and Emerging Risks (SCHEER).
Association between gender-based violence and hypertension among women in the Kyrgyzstan Republic
Authors: Abba Mustapha S. , Nduka Chidozie U. , Anjorin Seun , Uthman Olalekan A. 
Published: December 2022

Abstract
Background
Gender-based violence (GBV) is a significant global public health problem and the most prominent human rights violation severely impacting women’s health and wellbeing. Therefore, the aim of this study is to evaluate the association between gender-based violence and hypertension in Kyrgyzstan Republic.

Methods
This study was conducted using population-based data of women from the 2018 Kyrgyzstan Demographic and Health Survey. The odds ratio was calculated to measure the association between GBV and hypertension, and p-values < 0.005 was considered statistically significant.

Result
We included data of 4793 participants, and 621 (13%) of them had hypertension. Participants exposed to GBV were 24% more likely to have hypertension than unexposed participants (OR = 1.24, 95% CI: 1.03–1.48). Of all women with hypertension, 206 (33.0%) were exposed to GBV. Participants with secondary education or higher exposed to GBV were 24% more likely to be hypertensive than GBV unexposed women with the same education levels OR = 1.24, 95% CI: 1.04–1.49). Unemployed participants exposed to GBV were 45% more likely to develop hypertension than their unexposed counterparts (OR = 1.45, 95%CI: 1.15–1.81). Rural residents exposed to GBV were also 29% more likely to have hypertension than those unexposed to GBV (OR = 1.29, 95% CI: 1.04–1.59). The odds of hypertension among those exposed to GBV increase with age.

Conclusion
The study revealed that GBV is a significant factor of having hypertension among Kyrgyz women.
Lifeworld perspectives of people with dementia: a meta-aggregation of qualitative studies
Authors: Eriksen Siren , Engedal Knut , Grov Ellen Karine 
Published: December 2022

Abstract

Objectives
This meta-aggregation aims to interpret and synthesize present knowledge on the lifeworld perspectives of people with dementia and develop a model for guidance in clinical practice.

Method
The data consist of four meta-syntheses describing different lifeworld perspectives in accordance with van Manen’s existentials: lived relations, lived space, lived time and lived body. The meta-aggregation summarizes a range of views expressed by people with dementia in qualitative, interview-based studies, with the aim of generating a reliable model based on the studies’ findings.

Results
In total, 88 studies among 1,191 persons with dementia were included. Sixteen areas of focus were found, representing four perspectives: (a) lived relations, consisting of connectedness, independence, equality and competence; (b) lived space, consisting of belonging, meaningfulness, safety and security, and autonomy; (c) lived time, consisting of being rooted in the past, being in the present, viewing the future and being in process; and (d) lived body, consisting of being functional, trustworthy, adaptable and presentable. A model shaped as a tree trunk captures the lifeworld perspectives of people with dementia.

Conclusion
Sixteen areas were revealed from this meta-aggregation and form the basis of a model. This model may be used as a guide for health care personnel to ensure the overall lifeworld-perspectives of people with dementia in care for the target group and conduct lifeworld-preserving care with a person-centred approach.
IgA vasculitis presenting as nephrotic syndrome following COVID-19 vaccination: a case report
Authors: Cho Illeon , Kim Jwa-Kyung , Kim Sung Gyun 
Published: December 2022

Abstract
Background
Following the strong recommendation for coronavirus disease 2019 (COVID‑19) vaccination, many patients with medical comorbidities are being immunized. However, the safety of vaccination in patients with autoimmune diseases has not been well established. We report a new case of biopsy-proven IgA vasculitis with nephritis presenting as a nephrotic syndrome after mRNA COVID-19 vaccination in a patient with a history of leukocytoclastic vasculitis.

Case presentation
A 76-year-old man with a history of cutaneous leukocytoclastic vasculitis presented with purpura in both lower limbs, followed by nephrotic syndrome after the second dose of BNT162b2 mRNA COVID-19 vaccination. Skin and renal biopsy revealed IgA vasculitis with nephritis. The patient’s past medical history of leukocytoclastic vasculitis and features of chronicity in renal pathology suggest an acute exacerbation of preexisting IgA vasculitis after COVID-19 vaccination. After the steroid and renin-angiotensin system inhibitor use, purpura and acute kidney injury recovered within a month. Subnephrotic proteinuria with microscopic hematuria remained upon follow-up.

Conclusion
Physicians should keep in mind the potential (re)activation of IgA vasculitis following mRNA COVID-19 vaccines. It is important to closely monitor COVID-19 vaccinated patients, particularly those with autoimmune diseases.
Correlation of magnetic resonance images with neuropathology of irreversible metronidazole-induced encephalopathy: an autopsy case report
Authors: Miki Yasuo , Takeuchi Yuki , Murasawa Shingo , Takayasu Shinobu , Tsushima Fumiyasu , Kakeda Shingo , Mizukami Hiroki , Wakabayashi Koichi 
Published: December 2022

Abstract
Background
Neurological symptoms and radiographic abnormalities may remain in a small proportion of patients with metronidazole-induced encephalopathy (MIE). Although experimental animal models of MIE have suggested a Wernicke’s encephalopathy-like pathology, little is known about the histopathological features of MIE. Here we report the first autopsy case of irreversible MIE.

Case presentation
A 72-year-old Japanese woman with pancreatic neuroendocrine tumour and metastatic tumours in the liver developed intraabdominal bleeding from a hepatic abscess. She was administered metronidazole for 79 days (1.5 g/day), which caused dysarthria followed by hand tremor and altered mental status. Brain magnetic resonance imaging at the time of onset revealed hyperintensities in the deep white matter of the bilateral parietal lobes and splenium of the corpus callosum on diffusion-weighted imaging (DWI) with reduced apparent diffusion coefficient (ADC) values. Despite the improvement of dysarthria and hand tremor, her cognition remained affected even after the withdrawal of metronidazole. She died of pancreatic neuroendocrine tumour at the age of 74 years. Histopathological examinations of the brain confirmed a combination of severe demyelination and moderate axonal degeneration, which corresponded to the regions showing abnormal signal intensities on DWI with reduced ADC values. There were no pathological findings suggestive of Wernicke’s encephalopathy in the brain.

Conclusion
We have demonstrated the clinical, radiographic and histopathological aspects of irreversible MIE. Hyperintensities on DWI with reduced ADC values in affected regions may indicate a poor clinical prognosis due to irreversible pathological damage.
A qualitative exploration of influences on eating behaviour throughout pregnancy
Authors: Rockliffe Lauren , Smith Debbie M. , Heazell Alexander E. P. , Peters Sarah 
Published: December 2022

Abstract
Background:
Pregnancy is often conceptualised as a ‘teachable moment’ for health behaviour change. However, it is likely that different stages of pregnancy, and individual antenatal events, provide multiple distinct teachable moments to prompt behaviour change. Whilst previous quantitative research supports this argument, it is unable to provide a full understanding of the nuanced factors influencing eating behaviour. The aim of this study was to explore influences on women’s eating behaviour throughout pregnancy.

Methods:
In-depth interviews were conducted online with 25 women who were less than six-months postpartum. Interviews were audio-recorded and transcribed verbatim. Data were analysed thematically.

Results:
Five themes were generated from the data that capture influences on women’s eating behaviour throughout pregnancy: ‘The preconceptual self’, ‘A desire for good health’, ‘Retaining control’, ‘Relaxing into pregnancy’, and ‘The lived environment’.

Conclusion:
Mid-pregnancy may provide a more salient opportunity for eating behaviour change than other stages of pregnancy. Individual antenatal events, such as the glucose test, can also prompt change. In clinical practice, it will be important to consider the changing barriers and facilitators operating throughout pregnancy, and to match health advice to stages of pregnancy, where possible. Existing models of teachable moments may be improved by considering the dynamic nature of pregnancy, along with the influence of the lived environment, pregnancy symptoms, and past behaviour. These findings provide an enhanced understanding of the diverse influences on women’s eating behaviour throughout pregnancy and provide a direction for how to adapt existing theories to the context of pregnancy.
Interpersonal Psychotherapy’s problem areas as an organizing framework to understand depression and sexual and reproductive health needs of Kenyan pregnant and parenting adolescents: a qualitative study
Authors: Kumar Manasi , Yator Obadia , Nyongesa Vincent , Kagoya Martha , Mwaniga Shillah , Kathono Joseph , Gitonga Isaiah , Grote Nancy , Verdeli Helena , Huang Keng Yen , McKay Mary , Swartz Holly A. 
Published: December 2022

Abstract
Background
Peripartum adolescents experience significant interpersonal transitions in their lives. Depression and emotional distress are often exacerbated by adolescents’ responses to these interpersonal changes. Improved understanding of pregnancy-related social changes and maladaptive responses to these shifts may inform novel approaches to addressing the mental health needs of adolescents during the perinatal period. The paper aims to understand the sources of psychological distress in peripartum adolescents and map these to Interpersonal Psychotherapy’s (IPT) problem areas as a framework to understand depression.

Method
We conducted interviews in two Nairobi primary care clinics with peripartum adolescents ages 16–18 years (n = 23) with experiences of depression, keeping interpersonal psychotherapy framework of problem areas in mind. We explored the nature of their distress, triggers, antecedents of distress associated with an unplanned pregnancy, quality of their relationships with their partner, parents, and other family members, perceived needs, and sources of support.

Results
We found that the interpersonal psychotherapy (IPT) framework of interpersonal problems covering grief and loss, role transitions, interpersonal disputes, and social isolation was instrumental in conceptualizing adolescent depression, anxiety, and stress in the perinatal period.

Conclusion
Our interviews deepened understanding of peripartum adolescent mental health focusing on four IPT problem areas. The interpersonal framework yields meaningful information about adolescent depression and could help in identifying strategies for addressing their distress.
Relationship between dry eye and expressions of CXCR3 and CCR5 after ocular acid burn
Authors: Jiang Bo , Hu Qianqian , Li Tao , She Man , Li Chunxia , Zhou Xiaodong 
Published: December 2022

Abstract
Objective
To investigate the manifestation of dry eye and its relationship with CXCR3 and CCR5 expression in patients with ocular acid burns.

Methods
This is a case–control study. A total of 27 eyes of 22 cases ocular with acid burns of I-V degrees from Jan.2020 to Feb.2021 in Jinshan Hospital of Fudan University were selected as observation group, and 8 eyes of 8 cases of normal people were selected as control group. The follow-up period was 3 months. The visual acuity, intraocular pressure (IOP), corneal fluorescein staining scores (CFS), breakup time of tear film (BUT), Schirmer I test, corneal thickness and tear meniscus height (TMH) were observed at 1 day, 1 and 3 months after injury. The protein expressions of CXCR3 and CCR5 were examined by ELISA and compared among groups at each time point.

Results
BUT and Schirmer I tests value in the observation group were lower than those in the control group 3 months after injury (BUT: Group I ~ IV p = 0.0266, p = 0.0222, p = 0.0003, p = 0.0059, respectively; Schirmer I test: Group I ~ IV p = 0.0027, p = 0.0033, p = 0.0016, p = 0.0032, respectively). CFS scores were higher than those in the control group at 1 day after injury (all p < 0.0001), but decreased gradually at 1 and 3 months after injury (Group I ~ IV p = 0.0042, p = 0.0096, p < 0.0001, p < 0.0001, respectively). The corneal thickness and TMH 1 day after injury were higher than those in the control group (corneal thickness: Group II ~ IV p = 0.0010, p < 0.0001, p < 0.0001, respectively; TMH: Group II ~ IV p = 0.0002, p < 0.0001, p < 0.0001, respectively), and also higher than those at 1 month and 3 months after injury (corneal thickness: Group II ~ IV p = 0.0010, p < 0.0001, p < 0.0001, respectively; TMH: Group II ~ IV p = 0.0345 and p = 0.0045, p = 0.0005 and p < 0.0001, p = 0.0114 and p = 0.0019, respectively). The expression levels of CXCR3 and CCR5 protein were significantly negatively correlated with BUT (all p < 0.0001), and CXCR3 and CCR5 were also significantly negatively correlated with Schirmer I test value (p < 0.0001, p = 0.0004, respectively).

Conclusion
Ocular acid burns can cause dry eye, and the expression of CXCR3 and CCR5 protein in tears may be related to the occurrence of dry eye after ocular acid burn.