bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interim Financial Reporting: Theory and Practice in Ireland
Authors: Kirk Robert 
Published: April 2022

The paper investigates the accounting theory and practice in the preparation of interim financial statements with particular reference to the current regulatory framework contained within the Stock Exchange requirements. Recent developments are discussed including the proposals of the Cadbury Report and the ICAEW consultative document to improve the informational content of these reports. The main part of the paper investigates current practice in Ireland and outlines the weaknesses in the current system and puts forward a number of recommendations that should be seriously considered by a future standard setting body for incorporation into current practice.
The Role of high-resolution Magnetic Resonance Imaging at Different Stages of Subchondral Insufficiency Fracture in the Knee
Authors: Ivankov A. P. , Seliverstov P. V. 
Published: April 2022

The history of subchondral insufficiency fracture of knee is closely related to a pre-existing diagnosis of spontaneous osteonecrosis (SONK). Previously, it was believed that subchondral linear or lunate pathological changes on magnetic resonance imaging in elderly patients with osteoporosis are the result of spontaneous osteonecrosis that has occurred, but it was later found that a small proportion of patients with osteonecrosis of the femoral head initially have a failure fracture, then complicated by secondary osteonecrosis. The main methods for diagnosing subchondral insufficiency fracture are radiography and magnetic resonance imaging. Magnetic resonance imaging has demonstrated high information content in subchondral insufficiency fracture of knee.
Pengaruh Pengetahuan, Pengawasan dan Motivasi Kerja terhadap Kepatuhan K3 Pekerjaan di Ketinggian PT IBP Proyek Electrical Maintenance PHR
Authors: Putra Rahmad Praya 
Published: April 2022

Penelitian ini membahas mengenai bagaimana pengetahuan, pengawasan dan motivasi kerja berpengaruh terhadap kepatuhan K3 pekerjaan diketinggian PT IBP poryek electrical maintenance PHR. Tujuan penelitian ini adalah untuk mengetahui pengaruh pengetahuan, pengawasan dan motivasi kerja terhadap kepatuhan K3 pekerjaan diketinggian PT IBP proyek electrical maintenance PHR. Teknik pengambilan sampel menggunakan teknik sampling kuota dengan jumlah 59 responden yang berkaitan dengan penerapan K3 diketinggian. Alat uji analisis yang digunakan adalah SmartPLS v.3.3.5 dengan metode analisis SEM (Structural EquationModeling). Hasil penelitian ini menunjukkan bahwa pengetahuan berpengaruh positif dan signifikan terhadap kepatuhan K3, pengawasan berpengaruh positif dan tetapi tidak signifikan terhadap kepatuhan K3, motivasi berpengaruh positif dan signifikan terhadap kepatuhan K3, kinerja karyawan terbukti memediasi pengaruh kompensasi terhadap motivasi kerja. Variabel pengetahuan, pengawasan dan motivasi kerja berpengaruh sebesar 83.7% terhadap kepatuhan K3 pekerjaan diketinggian PT IBP proyek electricak maintenance PHR.Kata kunci: Pengetahuan, pengawasan, motivasi kerja
Mirar a través de la zona de contacto: aproximaciones a las prácticas letradas vernáculas de un estudiante
Authors: Libreros-Galicia Eduardo Daniel 
Published: April 2022

This paper presents an analysis of
the vernacular literacy practices that young
people share on social media through the case of
Esteban, a high school student whose activities
are negatively perceived by adults. This was done
through the perspective offered by the contact
zone, a theoretical construct that allowed us to
identify the social spaces where cultures interact,
often in contexts marred by asymmetrical relations
of power. Virtual ethnography was used to guide the
observation of Esteban’s social media, considering
mediated interaction as a social process, text as an
interaction, and the observer-observed relationship.
The method was broadened by an interview, to include the participant’s testimony about the creation of his vernacular literacy practices, as well as his experience on the contrasts between perceptions of his peers and those of the adults who
knew those practices. This case illustrates starting points to conduct pedagogical experiences based on the contact zone, to promote an approach to some students activities that are often stigmatized, helping to establish models of understanding them and the spaces where they take place.
ORNAMEN SEBAGAI ELEMEN ESTETIK PADA ISTANO BASA PAGARUYUNG
Authors: Putri Melati Soraya , Sundari Sri , Yulimarni Yulimarni 
Published: April 2022

The research which has the title “Ornament as aesthetic element on Istano Basa Pagaruyung” has been intended to further historical and ornament forms on Istano Basa Pagaruyung.. This research conducted in Kecamatan Tanjung Emas, Kabupaten Tanah Datar, West Sumatera. This research using qualitative method with descriptive data discuss about the data accordance with the facts found in the field, with aesthetic research. Data collection done through by study research, observation, interviews, and documentation. The motivating factor in doing this research is a rising an interest about ornament there in Istano Basa Pagaruyung edifice.Istano Basa Pagaruyung is traditional houses that has been use as a tourist object. These palaces have three floors. The first floor called as an “anjuang”. The second floor is an “Anjuang Paranginan” and the third floor called “Mahligai”. The aesthetic value that finds from the base palace is visible source various ornament in this edifice. Like the ornament in the wall, the grabbing wall in janjang or stairs, entrance, lipslang, attic and lower rafters and kasau or under the roof and on the head pole. The motives of the ornaments present in certain parts have a different purpose and meaning, according to the name of motives.ABSTRAK Penelitian yang berjudul “Ornamen Sebagai Elemen Estetik Pada Istano Basa Pagaruyung,” bertujuan untuk mendalami sejarah dan bentuk motif ornamen yang ada pada bangunan istano. Penelitian ini dilaksanakan di daerah Kecamatan Tanjung Emas, Kabupaten Tanah Datar, Sumatra Barat. Penelitian ini menggunakan metode kualitatif dengan data deskriptif yang membahas tentang data sesuai dengan fakta yang ditemui di lapangan, dengan kajian estetik. Pengumpulan data dilakukan melalui studi pustaka, observasi, wawancara, dan dokumentasi. Faktor pendorong dalam melakukan penelitian ini adalah timbulnya ketertarikan mengenai ornamen yang terdapat pada bangunan Istano Basa Pagaruyung. Istano Basa Pagaruyung merupakan rumah adat yang telah dijadikan sebagai objek wisata. Istano Basa Pagaruyung memiliki tiga lantai, lantai yang pertama disebut dengan “anjuang”, lantai kedua disebut dengan “anjuang paranginan” dan lantai tiga disebut dengan “mahligai”. Nilai estetik yang terdapat pada Istano Basa Pagaruyung ini terlihat dari berbagai macam ornamen yang terdapat pada bangunannya. Seperti ornamen yang terdapat pada bagian dinding, dinding pegangan janjang, pintu masuk, lisplang, loteng dan pinggiran loteng, kasau atau bawah atap, dan pada bagian kepala tiang. Motif – motif ornamen yang terdapat pada bagian – bagian tertentu memiliki maksud dan tujuan yang berbeda, sesuai dengan nama – nama motifnya. Kata kunci: Istano Basa Pagaruyung, nilai estetis, ornamen.
Komunikasi Non Verbal Dan Makna Pada Tayangan Kartun Jungle Beat-Munki And Trunk Season 4 Episode 3
Authors: Lani Oktri Permata , Maijar Andri , Fitri Miftahurrahmi 
Published: April 2022

Penelitian ini berusaha untuk mengkaji tayangan kartun Jungle Beat-Munki and Trunk season 4 episode 3 dengan menggunakan teori sistem nonverbal kategori kinesis dan proxemics sebagai acuan unit analisisnya. Penelitian ini bertujuan untuk menginterprestasikan makna pesan nonverbal dengan menggunakan metodologi visual Gillian Rose dari sisi site of self dan site of production untuk menemukan makna pesan nonverbal dalam tayangan kartun Jungle Beat-Munki and Trunk season 4 episode 3. Penelitian ini menggunakan paradigm kritis dengan pendekatan kualitatif yang memfokuskan pada adegan-adegan yang menggambarkan pesan nonverbal dalam visualisasi kartun Jungle Beat-Munki and Trunk. Hasil penelitian ini menemukan jika makna pesan nonverbal yang ditunjukkan dalam kartun Jungle Beat-Munki and Trunk season 4 episode 3 juga tercermin dari masalah yang ada dikehidupan saat ini seperti berjuang, menghormati, bersungguh-sungguh, dan bersabar. Kata Kunci: Komunikasi Nonverbal, Kinesis, Proxemis, Metodologi Visual ABSTRACT This study seeks to examine the cartoon show “Jungle Beat-Munki and Trunk season 4 episode 3” by using nonverbal systems theory kinesis and proxemics categories as a reference unit of analysis. This study aims to interpret the meaning of nonverbal messages using Gillian Rose's visual methodology from the site of self and site of production side to find the meaning of nonverbal messages in the cartoon show “Jungle Beat-Munki and Trunk season 4 episode 3”. This study uses a critical paradigm with a qualitative approach which focuses on scenes that depict nonverbal messages in the cartoon visualization “Jungle Beat-Munki and Trunk”. The results of this study found that the meaning of nonverbal messages shown in the cartoon “Jungle Beat-Munki and Trunk season 4 episode 3” is also reflected in the problems that exist in life today such as struggling, respecting, being serious, and being patient.
Respect and Empowerment in Second Language Education
Authors: Daniel Mayra 
Published: April 2022

Culturally responsive second language instruction requires educators focus on more than language. Language holds only part of the messages conveyed in intra and inter-personal communication. Effective lessons focus on the cultures of the speakers of the target language of study when they explore learners’ funds of knowledge, and then use the information this provides for the design of empowering curricula. This case study examined lessons prepared by 21 practicing teachers, representing 15 school districts in the northern Illinois area of the United States. Participants conducted an ethnography which was a required assignment in a post-graduate course focused on literacy instruction for emerging bilinguals. This work investigated educators’ ideologies of biliteracy and learner empowerment, and examined teachers’ visions of advocacy in reactions to course readings, in lesson design, and in the philosophy of multiliteracy statement.
Unterrichtsansatz und Lernsetting als entscheidende Faktoren für die Berücksichtigung individueller Bedürfnisse beim Fremdsprachenlernen
Authors: Suter Christoph 
Published: April 2022

Es ist unbestritten, dass es allen Menschen grundsätzlich möglich ist, in verschiedenen Sprachen kommunizieren zu lernen. Die Erfahrung zeigt jedoch auch, dass nicht alle Lernenden im Fremdsprachenunterricht gleichermassen kommunikative Kompetenzen erwerben. Dies gilt nicht nur, aber auch für Lernende mit diagnostiziertem sonderpädagogischem Förderbedarf.
Daraus ergibt sich eine zentrale Frage an die Fremdsprachendidaktik: Wie kann ein Fremdsprachenunterricht so gestaltet werden, dass alle Lerner/-innen mit ihren ganz unterschiedlichen Voraussetzungen kommunikative Kompetenzen in der Fremdsprache entwickeln können? Nur wenn es gelingt, ein Lernsetting zu gestalten, das allen die Möglichkeit zu Lernaktivitäten in ihrer Reichweite gibt, sind auch Lernschritte für alle möglich.
“I'll still kick your ass even in my skirt”.
Authors: Schlote Elke , Keller Stefan , Schülin Benedikt , Meier Niklaus 
Published: April 2022

In diesem Beitrag stellen wir dar, wie Schüler*innen der Sekundarstufe II (3. Schuljahr) sich im Fach Englisch vertieft mit der Darstellung von Feminismus in selbst ausgewählten Musikvideos auseinandergesetzt haben. Da dies eine detaillierte Analyse von Text-, Bild- und Musik-Elementen beinhaltete, wurde dafür eine speziell für den Unterricht entwickelte Web-App eingesetzt (TRAVIS GO). Der Beitrag zeigt didaktische Zugänge zur Umsetzung des Themas auf, und geht dabei spezifisch auf die Funktionalitäten von TRAVIS GO für die Analyse moderner Medien im Fremdsprachenunterricht ein. Ziel dabei ist die kritische Diskussion eines zentralen gesellschaftlichen Themas anhand authentischer Materialien, wobei sprachliches, ästhetisch-kulturelles und mediales Lernen verbunden werden.
A review of welfare indicators for sea turtles undergoing rehabilitation, with emphasis on environmental enrichment
Authors: Diggins R , Burrie R , Ariel E , Ridley J , Olsen J , Schultz S , Pettett-Willmett A , Hemming G , Lloyd J 
Published: April 2022

AbstractFor animals undergoing rehabilitation it is vital to monitor welfare in a way that is feasible, practical, and limits stress to the animal. The industry gold standard is to assess welfare under the Five Domains model, including nutrition, environment, physical health, and behaviour as the first four physical domains and mental domain as the fifth. Feasibility and effectiveness of these domains for assessing welfare of sea turtles undergoing rehabilitation were reviewed and it was determined that the mental state can be best assessed through behavioural changes. A scoping review of the literature was conducted using Scopus and Web of Science to investigate use of environmental enrichment devices (EEDs) as a measure of welfare in sea turtles. Behavioural assessments using EEDs were found to be well-documented; however, most EED studies pertained largely to livestock or zoo animals. Furthermore, studies rarely concentrated on reptiles, and specifically sea turtles. Results also showed that certain welfare assessment methods may be less appropriate for short-term captivity experienced during rehabilitation. Additionally, the hospital environment limits the ability to address some of the domains (ie biosecurity, feasibility, safety of turtle, etc, might be compromised). This review shows that only three of the nine environmental enrichment strategies described in the literature suit the specific requirements of sea turtles in rehabilitation: feeding, tactile, and structural. It is documented that turtles display behaviours that would benefit from EEDs and, therefore, more specific studies are needed to ensure the best welfare outcomes for sea turtles undergoing rehabilitation.
Assessment of the Effect of Electromagnetic Field on Bacterial Load and Physicochemical Properties of A Selected Food and Dairy Industry Effluent in Akure
Authors: A. M. Ilemobayo, , O. D. Teniola, 
Published: April 2022

Management of industrial effluents is one of the major challenges affecting developing nations of the world. Many of these industries release their effluents indiscriminately into the environment without proper treatment, which has caused a great health hazards to the environment and living population of this nation. The aim of this study was to determine the effect of electromagnetic field on microbial load of industrial effluents from food and dairy industry at Akure, Ondo state, Nigeria. Bacteria were isolated and identified using biochemical and molecular methods. Microbiological analysis and physicochemical characterization of the industrial effluent were carried out to determine the effect of electromagnetic field on microbial load and physicochemical parameters of the industrial effluents. Eleven bacteria were isolated from the effluents, the morphological, microscopic and biochemical characteristics of the eleven isolated bacteria suggests the isolates to be Bacillus cereus, Bacillus subtilis ,Enterobacter aerogenes, Enterococcus faecalis, Lactococcous lactis, Micoccocus luteus, Pseudomonas aeruginosa, Proteus vulgaris, Rhodococcus equi, Serratia marcesans and Staphylococcous aureus. It was observed that electromagnetic field (EMF) had significant effect on the bacterial load of the industrial effluent. Mean differences was considered significant at P≤0.05. Bacterial load decreases as the magnitude of the EMF increases with time. The physicochemical analysis of the raw and EMF treated effluents revealed that EMF treated effluent had lower mean values of physicochemical. This outcome of study shows that Electromagnetic field treatment of effluent is effective in reducing the bacterial load of food and dairy industrial effluents, hence making the effluent safe for the environment to which it will be discharged. The method for the treatment can be developed and modified for effective use in industrial settings which will be of great economic importance to food and dairy industries and waste water management of developing nations.
Natural Silk Spinning‐Inspired Meso‐Assembly‐Processing Engineering Strategy for Fabricating Soft Tissue‐Mimicking Biomaterials
Authors: Zhang Yuehua , Ye Shasha , Cao Leitao , Lv Zhuochen , Ren Jing , Shao Zhengzhong , Yao Yuan , Ling Shengjie 
Published: April 2022

AbstractNatural silk spinning is the strategy used by spiders and silkworms to construct their ultra‐strong‐and‐tough silks. It can be considered as an optimized meso‐assembly processing engineering (MAPE) strategy that effectively coordinates molecular‐and‐supramolecular assembly and native spinning. Inspired by this process, this study develops a biomimetic MAPE strategy to fabricate biomaterials mimicking the structural and mechanical characteristics of biological tissues. The structural and mechanical mimetics are realized by synergistically integrating phase transition‐induced meso‐assembly and mechanical training‐induced structural remodeling. Through this approach, highly‐hydrated silk fibroin materials with exceptional tunable mechanical properties, such as softness, high stretchability (failure strain larger than 1200%), and high strength and toughness (strength of 5 ± 1 MPa, stiffness 18 ± 2 MPa, and toughness of 6 ± 1 MJ m−3) are produced. Thanks to their structural and mechanical tissue‐matching features, these biomimetic meso‐assembled materials exhibit advances in the modulation of different cell morphologies. The gradient architecture deformation (aspect ratio, spreading area, and perimeter) is evidenced, and the interplay between cytoskeleton (actin and tubulin) and matrix adaptation orientation is substantiated. These findings advance the application of silk fibroin biomaterials in the regulation of adaptive cell reconstruction, since the morphology of cells is the basis for their physiological functions.
Targeted Delivery of DNA Topoisomerase Inhibitor SN38 to Intracranial Tumors of Glioblastoma Using Sub‐5 Ultrafine Iron Oxide Nanoparticles
Authors: Li Yuancheng , Xie Manman , Jones Joshua B. , Zhang Zhaobin , Wang Zi , Dang Tu , Wang Xinyu , Lipowska Malgorzata , Mao Hui 
Published: April 2022

AbstractEffectively delivering therapeutics for treating brain tumors is hindered by the physical and biological barriers in the brain. Even with the compromised blood–brain barrier and highly angiogenic blood–tumor barrier seen in glioblastoma (GBM), most drugs, including nanomaterial‐based formulations, hardly reach intracranial tumors. This work investigates sub‐5 nm ultrafine iron oxide nanoparticles (uIONP) with 3.5 nm core diameter as a carrier for delivering DNA topoisomerase inhibitor 7‐ethyl‐10‐hydroxyl camptothecin (SN38) to treat GBM. Given a higher surface‐to‐volume ratio, uIONP shows one‐ or three‐folds higher SN38 loading efficiency (48.3 ± 6.1%, mg/mg Fe) than those with core sizes of 10 or 20 nm. SN38 encapsulated in the coating polymer exhibits pH sensitive release with <10% over 48 h at pH 7.4, but 86% at pH 5, thus being protected from converting to inactive glucuronide by UDP‐glucuronosyltransferase 1A1. Conjugating αvβ3‐integrin‐targeted cyclo(Arg‐Gly‐Asp‐D‐Phe‐Cys) (RGD) as ligands, RGD‐uIONP/SN38 demonstrates targeted cytotoxicity to αvβ3‐integrin‐overexpressed U87MG GBM cells with a half‐maximal inhibitory concentration (IC50) of 30.9 ± 2.2 nm. The efficacy study using an orthotopic mouse model of GBM reveals tumor‐specific delivery of 11.5% injected RGD‐uIONP/SN38 (10 mg Fe kg−1), significantly prolonging the survival in mice by 41%, comparing to those treated with SN38 alone (p < 0.001).
Cells‐Micropatterning Biomaterials for Immune Activation and Bone Regeneration
Authors: Zhang Bingjun , Han Fei , Wang Yufeng , Sun Yuhua , Zhang Meng , Yu Xiaopeng , Qin Chen , Zhang Hongjian , Wu Chengtie 
Published: April 2022

AbstractNatural tissues are composed of ordered architectural organizations of multiple tissue cells. The spatial distribution of cells is crucial for directing cellular behavior and maintaining tissue homeostasis and function. Herein, an artificial bone bioceramic scaffold with star‐, Tai Chi‐, or interlacing‐shaped multicellular patterns is constructed. The “cross‐talk” between mesenchymal stem cells (MSCs) and macrophages can be effectively manipulated by altering the spatial distribution of two kinds of cells in the scaffolds, thus achieving controllable modulation of the scaffold‐mediated osteo‐immune responses. Compared with other multicellular patterns, the Tai Chi pattern with a 2:1 ratio of MSCs to macrophages is more effective in activating anti‐inflammatory M2 macrophages, improving MSCs osteogenic differentiation, and accelerating new bone formation in vivo. In brief, the Tai Chi pattern generates a more favorable osteo‐immune environment for bone regeneration, exhibiting enhanced immunomodulation and osteogenesis, which may be associated with the activation of BMP‐Smad, Oncostatin M (OSM), and Wnt/β‐catenin signaling pathways in MSCs mediated by macrophage‐derived paracrine signaling mediators. The study suggests that the manipulation of cell distribution to improve tissue formation is a feasible approach that can offer new insights for the design of tissue‐engineered bone substitutes with multicellular interactions.
Traceless Benzylic C−H Amination via BifunctionalN‐Aminopyridinium Intermediates
Authors: Roychowdhury Pritam , Herrera Roberto G. , Tan Hao , Powers David C. 
Published: April 2022

AbstractC−H amination reactions provide the opportunity to streamline the synthesis of nitrogen‐containing organic small molecules. The impact of intermolecular C−H amination methods, however, is currently limited the frequent requirement for the amine precursors to bear activating groups, such asN‐sulfonyl substituents, that are both challenging to remove and not useful synthetic handles for subsequent derivatization. Here, we introduce traceless nitrogen activation for C−H amination—which enables application of selective C−H amination chemistry to the preparation of diverseN‐functionalized products—via sequential benzylic C−HN‐aminopyridylation followed by Ni‐catalyzed C−N cross‐coupling with aryl boronic acids. Unlike many C−H amination reactions that provide access to protected amines, the current method installs an easily diversifiable synthetic handle that serves as a lynchpin for C−H amination, deaminative N−N functionalization sequences.
In Vivo Production of Diverse β‐Amino Acid‐Containing Proteins
Authors: Lakis Edgars , Magyari Sarolt , Piel Jörn 
Published: April 2022

AbstractThe wide range of moieties installed in ribosomally synthesized and post‐translationally modified peptides (RiPPs) suggests largely untapped potential for protein engineering. However, many RiPP maturases recognize target peptide precursors through an N‐terminal leader sequence that is challenging to adapt to proteins. We have recently reported a family of enzymes that splice XYG sites in RiPPs to install α‐keto‐β‐amino acids. Backbone modifications influence diverse protein properties, yet the toolkit to install β‐amino acids is limited. Here we report their leader‐independent incorporation into proteins in E. coli. Integrating an 11‐residue splice tag into six different proteins permitted the site‐selective introduction of β‐residues in vivo. The motif fusion at C‐, N‐terminal, and internal positions yielded various β‐residues. Our approach complements the few existing methods to introduce β‐amino acids or ketone‐bearing moieties, suggesting diverse applications in chemical biology.