bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distal Transradial Access for Recanalization of Chronic Occlusions of the Radial Artery
Authors: Salo Sergii V. , Gavrylyshyn Andrii Yu. , Levchyshyna Olena V. , Shpak Sergii S. 
Published: June 2022

Background. The current state of interventional cardiology is aimed at reducing the number of probable complica-tions of procedures and increasing patient comfort. That is why there was a stage evolution of changing endovascular ap-proaches from transfemoral to transradial. But despite the significant benefits of transradial access, it leaves behind some important complications. One such complication is occlusion of the radial artery. The frequency of this situation ranges from 1 to 30%. That is why the world’s leading interventionists are increasingly using distal transradial access, which is associated with fewer cases of postoperative occlusion of the radial artery.
The aim. Occlusion of the radial artery is not an obstacle to changing access to the contralateral artery or more dan-gerous transfemoral access. With distal transradial access it is possible to recanalize artery and provide target procedure.
Materials and methods. The study included 318 patients who were scheduled for re-intervention. Among these patients, 12 had a radial artery occlusion, which is 3.7% of the total control group. Successful recanalizations with distal access were performed in 9 patients (75%), and in 3 patients (25%) the attempts were unsuccessful. The technique of recanalization of chronic occlusion included selection of hydrophilic, both non-coronary and coronary wires. At the end of the procedure, hemostasis was performed according to standard procedures using aseptic bandages. Complications of hemostasis were not detected in any patient in the control group. The postoperative period was unremarkable.
Conclusions. The study showed the possibility of using distal transradial access to recanalize chronic occlusions of the radial artery, which allows not to waste time on replacement of the contralateral radial artery or life-threatening transfemoral access and perform the necessary amount of the intervention. Besides, this preserves the radial artery for further use in bypass surgery or hemodialysis arteriovenous fistula.
Surgical Treatment of Cardiac Tumors Combined with Coronary Pathology
Authors: Vitovskyi Rostyslav M. , Kupchynskyi Oleksandr V. , Martyshchenko Ihor V. , Serdiuk Maryna M. , Kupchinsky Volodymyr O. , Isaienko Volodymyr V. 
Published: June 2022

Introduction. Cardiac tumors (CT) occur in 0.3-0.7% of general population according to autopsies. The combination of CT with coronary artery disease (CAD) significantly complicates the clinical course of the disease.
The aim. To study the frequency, features of the course and surgical treatment of patients with CT combined with CAD.
Materials and methods. In the period from 01.01.1969 to 31.12.2020, surgical treatment of 976 patients with CT was performed at the National Amosov Institute of Cardiovascular Surgery of the NAMS of Ukraine, and 41 (4.2%) of these patients had lesions of the coronary arteries. In 39 patients (95.1%), CT were represented by benign tumors (myxomas), in 2 (2.4%) by malignant, poorly differentiated sarcoma and immature teratoma. For the correction of the pathology of coronary vessels, a whole range of surgical methods was used: stenting of left anterior descending artery (LAD), which was performed immediately before surgery to remove CT, in 3 patients (7.3%); coronary artery bypass grafting in 35 patients (85.4%); in cases of the presence of a muscular bridge that narrowed the LAD, dissection of this structure was performed in 2 patients (4.9%); left ventricular aneurysm repair surgery in 1 patient (2.4%). In 7 patients (17.1%), the operation was performed on urgent indications.
Results. The average number of grafted arteries was 1.9 ± 0.3 (1 to 4) per patient. There were no mortality. Of the 41 patients with coronary artery lesions with CT, there were 2 cases of acute CAD as a result of their embolism by tumor fragments. Clinical manifestations in these patients differed significantly.
Conclusions. Occurrence of coronary artery embolism in patients with CT according to our data is 0.2% of all patients with CT. CAD accompanies tumor lesions in 4.1% of cases and is diagnosed by angiography and computed tomography. To correct the lesion of the coronary arteries in CT, the full range of surgical techniques is used, including stenting of the coronary artery (spacecraft), coronary artery bypass grafting, removal of the myocardial bridge.
Analisis Jalur Kritis Penjadwalan Proyek Dengan Metode Critical Path Method (CPM) Menggunakan Aplikasi Microsoft Project Pada Masa Pandemi Covid-19
Authors: Alan Muin Oskar Ezra 
Published: June 2022

Abstrak
Keterlambatan proyek mempengaruhi kualitas dan kuantitas pekerjaan apabila tidak dilakukan antisipasi pelaksanaan yang benar, baik pada metode pelaksanaan, koordinasi antara owner¸ kontraktor pelaksana dan konsultan manajemen konstruksi. Diperlukan metode antisipasi guna pekerjaan dilakukan sesuai schedule, Critical Path Method (CPM) dilakukan untuk menentukan jalur kritis pekerjaan, estimasi perkiraan item pekerjaan yang tidak memiliki free time (Float). Item pekerjaan yang melewati jalur kritis dapat dilakukan percepatan baik dengan penambahan perkerja (manhour) atau waktu kerja (workhour), jalur kritis yang didapatkan mayoritas merupakan pekerjaan struktur dengan rincian sebagai berikut, C-E1-E2-E3-E4-E5- E6-E7-E8-E9-10-E11-E12-E13-E14-E15-E16-E17-E18, pekerjaan struktur lantai 1 dengan elevasi + 0,00 hingga struktur atap baja pada elevasi +84,55.
Abstract
Project delays affect the quality and quantity of work if the correct implementation anticipation is not carried out, both in the method of implementation, coordination between owners, implementing contractors, and construction management consultants. An anticipation method is needed so that work is carried out according to schedule, Critical Path Method (CPM) is carried out to determine the critical path of work, estimates of work items that do not have free time (Float). Work that passes through the critical path can be done quickly by adding additional workers (manhour) or working time (working hours), the critical path is obtained as the main job with the following details, C-E1-E2-E3-E4-E5-E6-E7-E8-E9-10-E11-E12-E13-E14-E15-E16-E17-E18, from first based in elv. +0,00 until steel top on elv +84.55.
Perbandingan Produktivitas Pekerja Di Lapangan Dengan Permen PUPR 2022 Pada Proyek Guest House Exindo 57 Kabupaten Nganjuk
Authors: Diana Vina Shofi 
Published: June 2022

Abstrak
Keberhasilan pada pelaksanaan proyek konstruksi salah satunya ditentukan oleh produktivitas tenaga kerja yang baik. Pekerja proyek konstruksi harus bekerja secara efektif dan efisien, dan dengan produktivitas yang tinggi serta harus bekerja sesuai dengan rencana yang telah di tetapkan oleh kontraktor. Namun pada prakteknya, beberapa proyek konstruksi produktivitas tenaga kerja di lapangan berbeda dengan produktivitas yang telah ditetapkan oleh Permen PUPR No. 1 Tahun 2022. Penelitian ini menganalisis produktivitas tenaga kerja di lapangan dan membandingkannya dengan PUPR Tahun 2022 pada Proyek Pembangunan Guest House Exindo 57 Nganjuk dengan hasil penelitian pada pekerjaan penulangan kolom sebesar 0,63 Kg/OH, penulangan balok sebesar 1,37 Kg/OH, dan penulangan pelat lantai sebesar 0,50 Kg/OH. Pada pekerjaan bekesting kolom sebesar 3,58 m²/OH, bekesting balok sebesar 3,52 m²/OH, dan bekesting pelat lantai sebesar 4,77 m²/OH. Pada pekerjaan pengecoran kolom sebesar 12,72 m³/OH, pengecoran balok sebesar 20,14 m³/OH, dan pengecoran kolom sebesar 22,83 m³/OH.
Abstract
One of the successes in the implementation of construction projects is determined by good labor productivity. Construction project workers must work effectively and efficiently, and with high productivity and must work according to plans that have been set by the contractor. However, in practice, several construction projects have different labor productivity from the productivity set by the Permen PUPR No. 1 Tahun 2022. This study analyzes labor productivity in the field and compares it with PUPR 2022 at the Exindo 57 Nganjuk Guest House Development Project with research results on column reinforcement work of 0.63 Kg/OH, beam reinforcement of 1.37 Kg/OH, and plate reinforcement floor by 0.50 Kg/OH. The column formwork is 3.58 m²/OH, the beam formwork is 3.52 m²/OH, and the floor slab formwork is 4.77 m²/OH. In the column casting work the amount is 12.72 m/OH, the beam casting is 20.14 m/OH, and the column casting is 22.83 m/OH.
Practice of Coalition Government and its Effect on Current Economic Policy of Nepal
Authors: Dhakal Chandra Prasad 
Published: June 2022

In the context of Nepal, economic policy is guided by constitution and law. However, to some extent economic policy is guided by the manifesto of political parties and interest of key political leader. Theoretically, Nepalese economic policy is broadly guided by either socialist or capitalist ideology. Since the establishment of republic in Nepal, economic policy is guided by agenda of communist party. In this context, the study analyzes how the policy of coalition government impact overall economic plan of Nepal. The study followed the qualitative research design that analyzed the issue raised in research questions. Secondary sources of data were used for this study and conclusion of this study has been made on the basis of secondary source of the data. On the basis of data analysis, it is found that coalition government directly influenced on the economic policy of Nepal because political parties try to incorporate their minimum policy in governmental policy.
Global re-emergence of human monkeypox: Population on high alert
Authors: Banerjee Indrajit , Robinson Jared , Sathian Brijesh 
Published: June 2022

The Monkey pox virus is a member of the Orthopoxvirus genus in the family “Poxviridae”. The Orthopoxvirus genus includes Monkey pox, Smallpox (variola virus), the vaccinia virus and the Cowpox virus. The first human case of Monkey pox was recorded in the 1970’s in the (DRC) Democratic Republic of the Congo. Numerous cases of Monkey Pox have been reported to the WHO since the 1st of January 2022. As of the 15th of June 2022, a total of two thousand one hundred and three (2103) confirmed cases and 1 death have been registered by the WHO. Transmission of the Monkey Pox virus occurs through direct contact. Close contact such as that of skin to skin, mouth to mouth and face to face with the exposure to open lesions or lesions of the buccal mucosa aid the transmission of the disease. The virus is also transmitted through contaminated objects and materials ranging from pillows to bedding and the like. The occurrence and spread of this most recent outbreak of the virus has been mainly attributed to the sexual route of transmission. The sexual transmission predominantly occurring in men whom have had sexual relations with other men. Cases infected with Monkey Pox present with a high fever (pyrexia), vesicular and pustular rashes on the palms and soles and lymphadenopathy (lymphadenopathy being the main differentiating fever between Small Pox and Monkey Pox). Currently no licensed treatments are available for individuals infected with Monkey Pox, but brincidofovir and tecovirimat have shown promising use and efficacy against the virus in animals. The treatment is predominantly of the symptomatic type including paracetamol to combat the viral fever. Various medicaments can be used to prevent and control the Monkey Pox outbreak including (VIG) Vaccinia immunoglobulin, cidofovir and the Small Pox vaccine
The current international outbreak of Monkey Pox, is by no means the next SARS-CoV-2 pandemic, however through stronger global surveillance and international collaboration the current up flaring of cases can be swiftly controlled. It is vital that such outbreaks of this virus induce health agencies to begin further research into the Poxviridae family and formulate newer and more effective specific treatments to adequately treat and prevent such events in future.
A Preliminary Study on the Anti-dengue Viral Activity of Munronia pinnata
Authors: K.G. Jayasekara  , S.S.S.B.D.P Soysa  , T.S. Suresh3  , C.L. Goonasekara  , K.M. Gunasekera  
Published: June 2022

Dengue infection is a major health care problem in tropical and subtropical countries. The recently approved dengue vaccine has limitations, and there is no antiviral drug for treatment at present.For centuries plants and plant extracts have been used in traditional medicine for the treatment of various infections. The whole plant of Munronia pinnata, which has been used for treating fever patients in Sri Lankan traditional medicine, was tested for anti-dengue viral activity.The cytotoxicity assay of M. pinnata on Vero cells using 4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) revealed Maximum Nontoxic Dose (MNTD) as 125 μg/ml and 50% cytotoxic concentration (CC50) as 428.9 ± 21.55 μg/ml. Plaque reduction antiviral assay performed on dengue-4 virus infected Vero cells demonstrated half-maximal inhibitory concentration (IC50) as 26.12 ± 0.91 μg/ml. The selectivity index (SI) of Dengue infection is a major health care problem in tropical and subtropical countries. The recently approved dengue vaccine has limitations, and there is no antiviral drug for treatment at present.For centuries plants and plant extracts have been used in traditional medicine for the treatment of various infections. The whole plant of Munronia pinnata, which has been used for treating fever patients in Sri Lankan traditional medicine, was tested for anti-dengue viral activity.The cytotoxicity assay of M. pinnata on Vero cells using 4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) revealed Maximum Nontoxic Dose (MNTD) as 125 μg/ml and 50% cytotoxic concentration (CC50) as 428.9 ± 21.55 μg/ml. Plaque reduction antiviral assay performed on dengue-4 virus infected Vero cells demonstrated half-maximal inhibitory concentration (IC50) as 26.12 ± 0.91 μg/ml. The selectivity index (SI) of M. pinnata was 16.42.Based on the selectivity index, Munronia pinnata appears to be a viable candidate for identifying biologically active compounds with anti-dengue viral activity.Keywords: Dengue, Munronia pinnata, Antiviral, Plaque reduction Assay, Vero Cells was 16.42.Based on the selectivity index, Munronia pinnata appears to be a viable candidate for identifying biologically active compounds with anti-dengue viral activity.
Keywords: Dengue, Munronia pinnata, Antiviral, Plaque reduction Assay, Vero Cells
Synthesis, Characterization and Remarkable Anticancer Activity of Rhenium Complexes Containing Biphenyl Appended NNN Donor Sulfonamide Ligands
Authors: Chiranthi Kaushalya  , Taniya Darshani  , Sameera R Samarakoon  , Frank R Fronczek  , Inoka C Perera  , Theshini Perera  
Published: June 2022

Neutral and cationic rhenium complexes provide both hydrophilic as well as hydrophobic properties due to the robustness of the tridentate ligand system of biphenyl appended dipicolylamine (N(SO2bip)dpa) and diethylenetriamine (N(SO2bip)dienH) coordinated to the [Re(CO)3]+ core, hold immense potential for the development of metal based anticancer drugs. This was achieved by the synthesis of two ligands (L1: N(SO2bip)dpa and L2: (N(SO2bip)dienH) and their corresponding Re complexes (C1: [Re(CO)3(N(SO2bip)dpa)]PF6 and C2: [Re(CO)3(N(SO2bip)dien)] in good yield and high purity. All four compounds were characterized by 1H NMR, UV-Vis, FTIR spectroscopies and L1, also by single crystal X-ray diffraction. The methylene protons observed as a singlet at (4.59 ppm) in a 1H NMR spectrum of L1 appear as two doublets (5.66 and 4.65 ppm) in the spectrum of C1. The appearance of NH signals at 3.48, 5.17 and 6.69 ppm in the 1H NMR spectrum of C2 confirm the coordination of L2 with Re. The stretching vibration frequencies depicted by the S-N bond at 923 cm-1 for L1 appear towards lower frequencies (821 cm-1) in an FTIR spectrum of C1, while the S-N bond at 943 cm-1 for L2 appears towards higher frequencies (968 cm-1) in C2. In silico assessment of drug likeliness revealed zero violations demonstrating a high likeliness of the ligands to be successful as drug leads. All four compounds have shown very low IC50 values against non-small cell lung cancer cells (NCI-H292). Therefore, L1, C1, L2 and C2 are promising novel compounds that can be further investigated as potential anticancer agents.
Keywords: Rhenium Tricarbonyl, Sulfonamide, Anticancer, Fluorescence.
Biyoplastikler / Biyopolimerler: Ne Kadar Farkındayız?
Authors: IŞITAN Arzum , GÖK Cem , SULAK Mine , KIRMIZI Fatma , ONAR Volkan , KUTLUBAY Ramazan Çağrı 
Published: June 2022

Today, polymers have found a wide range of uses from kitchen utensils to artificial heart valves, thanks to their lightness, easy shaping, corrosion resistance, and cheapness. A large number of polymers are used in the packaging of food, textiles, and machinery, and they are an important part of solid waste disposed of in landfills. In addition, microplastics, which are small particles under 5 mm, pose a major problem in the pollution of rivers, lakes, seas, and oceans and increase our carbon footprint. Many strategies are being developed in parallel with the Green Deal to reduce both all the negative effects caused by polymers and our carbon footprint. According to the European Green Deal, reducing waste, compensating for carbon footprint emissions, and protecting resources and sustainability are key priorities for the EU now and in the future. Reusability and biodegradable polymer production are important parts of these strategies. The scientific works demonstrated the opportunity for renewable, biodegradable biopolymers to replace their synthetic counterparts in a variety of /application. Biopolymer is a type of polymer and a biodegradable chemical compound that is produced by living beings in the ecosphere. Biopolymers obtained from natural materials (e.g. alginate, zein, gelatin, agar, and chitin/chitosan) are highly abundant but underexploited renewable biomasses. Besides their natural biological and structural functions, the biopolymers can be tailored to new biomaterials with novel functionalities. The roles of biopolymers in obtaining environmentally friendly materials are very important for the future of the world.
So, are we aware of plastic pollution and ways to reduce it? Is there enough awareness in academia, industry, and society for biopolymers that are so important for a sustainable environment? In this study, the answers to these questions are researched and discussed.
UJI EFEKTIFITAS EKSTRAK ETANOL DAUN PEPAYA (Carica papaya Linn) SEBAGAI LARVASIDA Aedes aegypti
Authors: Maulana Muhammad , Hidayah Nurul , Nugraha Dyan Fitri , Kusuma I Ketut Gunawan 
Published: June 2022

Demam Berdarah Dengue (DBD) adalah penyakit yang dapat disebabkan oleh virus dengue yang tergolong Arthropod-Borne Virus, genus Flavivirus, dan family Flaviviridae. Demam Berdarah Dengue (DBD) ditularkan melalui gigitan nyamuk dari larva Aedes, terutama Aedes aegypti. Mengatasi kondisi tersebut secara empiris dengan menggunakan Carica papaya Linn yang memiliki potensi sebagai Larvasida. Penelitian ini bertujuan untuk mengetahui efektivitas ekstrak etanol daun papaya (Carica papaya Linn) sebagai larvasida nyamuk Aedes aegypti. Penelitian ini merupakan penelitian eksperimental menggunakan larva uji sebanyak 525 ekor. Larva uji dipilih secara acak kemudian dibagi dalam 7 kelompok. Perlakuan tiap kelompok terdiri dari kelompok kontrol negative (Aquadest), kontrol positif (abate), konsentrasi 0,2%, konsentrasi 0,4%, konsentrasi 0,6%, konsentrasi 0,8%, dan konsentrasi 1%. Terdapat perbedaan yang signifikan pada konsentrasi 0,2% jika dibandingkan dengan kontrol positif dan kontrol negatif, konsentrasi 0,2% adalah dosis terendah yang mampu membunuh larva Aedes aegypti dengan persentase kematian 77,38% dengan nilai signifikansi (p<0,05). Konsentrasi ekstrak daun papaya berpengaruh terhadap kematian larva aedes aegypti dengan nilai LC50 dalam rentang waktu 24 jam didapatkan pada konsentrasi 0,194%.
ANALISIS PENYALAHGUNAAN NAPZA PADA MAHASISWA KESEHATAN MASYARAKAT UNISKA MAB BANJARMASIN
Authors: Ikhsan Putri Maulidawati , Anam Khairul , Rizal Achmad , Ilmi M. Bahrul 
Published: June 2022

Penyalahgunaan NAPZA merupakan salah satu isu kesehatan yang sangat diperhatikan di seluruh dunia, dengan akses internet yang mudah diakses pun membuat permasalahan semakin serius. Tahun 2019, Kalimantan Selatan memiliki prevalensi penyalahgunaan narkotika diusia populasi 10-59 tahun sebanyak 55,598 Jiwa (1,98%). Jumlah pengguna Instagram di Indonesia pada November 2019 sebanyak 61 juta terdiri dari 50,8% perempuan dan 49,2% laki-laki. Sebanyak 41% pengguna media sosial berumur dewasa awal memiliki koleksi foto dan pesan membahas NAPZA. Tujuan penelitian ini mengetahui hubungan antara media sosial, pengetahuan dan sikap terhadap penyalahgunaan NAPZA di Fakultas Kesehatan Masyarakat Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin Tahun 2021. Metode penelitian menggunakan kuantitatif dengan cross sectional. Populasi penelitian ini adalah seluruh Mahasiswa Fakultas Kesehatan Masyarakat Universitas Islam Kalimantan Muhammad Arsyad Al Banjari berjumlah 1.391 orang dengan sampel sebanyak 95 orang menggunakan teknik Simple Random Sampling. Instrumen yang digunakan adalah google form, dianalisis menggunakan uji chi square (p < 0,05). Hasil penelitian menunjukkan media sosial tidak memiliki hubungan terhadap penyalahgunaan NAPZA (p value = 1,000), tidak ada hubungan antara pengetahuan dan penyalahgunaan NAPZA (p value = 0,345), serta tidak ada hubungan antara sikap dan penyalahgunaan NAPZA (p value= 1,000). Mahasiswa diharapkan untuk menghindari menggunakan NAPZA maupun berhenti menggunakan dengan pergi ke orang yang memiliki profesi sesuai seperti psikiater.