bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bridging the gap: An approach to reporting antimicrobial stewardship metrics specific to solid organ transplant recipients
Authors: Greenlee Sage B. , Acosta Tommy J. Parraga , Makowski Charles T. , Kenney Rachel M. , Ramesh Mayur , Williams Jonathan D. , Alangaden George J. 
Published: October 2022

AbstractBackgroundThis study seeks to describe inpatient antimicrobial use (AU) utilizing the National Healthcare Safety Network‐AU (NHSN‐AU) framework among solid organ transplant recipients (SOTr) within 12 months after transplant.MethodsThis cross‐sectional study included SOTr ≥ 18 years of age who underwent transplantation from January 2015 to December 2016 at a Midwestern US transplant center. Inpatient AU was followed for 12 months post‐transplant. Hospital days present up to 12 months post‐transplant, AU variables, and Clostridioides difficile infection (CDI) occurrences were analyzed.ResultsThe cohort of 530 SOTr included 225 kidney (42.5%), 171 liver (32.3%), 45 lung (8.5%), 40 heart (7.5%), 39 multivisceral (7.4%), seven small bowel (1.3%), and three pancreas (0.6%) transplants. Total days of therapy (DOT) were 22 782 among the cohort, with a median of 5 days [interquartile range [IQR], 1–12]. Lung and liver transplants had the most total DOT (6571 vs. 5569 days), while lungs and small bowels had the highest median DOT (13 [IQR, 2–56] vs. 12 [IQR, 2–31]). The facility‐wide DOT/1000 days were lowest in pancreas and highest in lung transplants (5.3 vs. 428.1). Small bowel transplants received the most resistant‐Gram‐positive infection and hospital‐onset infection agents for facility‐wide DOT/1000 days present. Pancreas and kidney transplants accounted for the most high‐risk CDI agents. CDI occurred in 34 patients, with kidney and liver transplants experiencing 13 each.ConclusionThis study represents one of the first reports of AU in SOTr utilizing the NHSN‐AU framework. More studies are needed for further peer‐to‐peer comparison of AU in this complex patient population.
image
Antimicrobial stewardship in solid organ transplantation: Perspective from a Veterans Affairs Medical Center
Authors: Felkner Rebecca , Barnett Susanne G. , Misch Elizabeth A. , Safdar Nasia , Balasubramanian Prakash 
Published: October 2022

AbstractBackgroundThe importance of antimicrobial stewardship (AMS) activities specifically focused on solid organ transplant (SOT) recipients is increasingly recognized. In 2014, the Veterans Health Administration (VHA) created national guidance and committed resources to establish AMS programs at Veterans Affairs (VA) medical centers across the country. However, the AMS implementation is at the discretion of individual VA centers.MethodsWe undertook an environmental scan of AMS activities in a tertiary care VA medical center.ResultsWe describe AMS activities focused on SOT recipients. Strategies based on local epidemiology that leverage the electronic medical record together with engagement by transplant infectious diseases personnel are likely to be beneficial.ConclusionAMS in SOT recipients is challenging yet impactful. Strategies described here may be useful for AMS activities focused on the SOT population.
Transplant surgeons’ perspective on antimicrobial stewardship: Experience with TransQIP
Authors: Shwaartz Chaya , Reichman Trevor W. 
Published: October 2022

AbstractAntimicrobial stewardship programs (ASPs) have been shown to reduce the rates of antimicrobial resistance and improve morbidity and mortality in surgical patients. ASPs have largely been underutilized in solid organ transplant programs, and the current state of ASPs in transplantation is reviewed. Continued implementation of ASPs would likely significantly benefit transplant patients. Furthermore, coupling ASPs with robust programmatic metrics (such as transplant‐specific NSQIP) will hopefully lead to improved outcomes including morbidity and mortality of solid organ transplant recipients.
Energy-Based Footstep Planning of Biped on Uneven Deformable Terrain Using Nonlinear Inverted Pendulum
Authors: Gora Sunil , Gupta Shakti S. , Dutta Ashish 
Published: October 2022

Abstract
In this work, the motion of a nonlinear inverted pendulum (NIP) on deformable terrain due to foot contact forces is used for energy analysis and footstep placement. In order to include the linear and rotational motions of the NIP, the mass moment of inertia of the body is also considered in the center of mass (CoM) model. The terrain deformation is modeled using a spring-damper contact model, and based on the rigid body dynamics of the NIP, its motion is generated. The energy analysis of the system provides the regions of possible foot placement. Based on the loss of potential energy due to ground deformation, the limits of terrain stiffness are also obtained for walking on uneven deformable terrain.
MVGCN: Multi-View Graph Convolutional Neural Network for Surface Defect Identification Using Three-Dimensional Point Cloud
Authors: Wang Yinan , Sun Wenbo , Jin Jionghua (Judy) , Kong Zhenyu (James) , Yue Xiaowei 
Published: October 2022

Abstract
Surface defect identification is a crucial task in many manufacturing systems, including automotive, aircraft, steel rolling, and precast concrete. Although image-based surface defect identification methods have been proposed, these methods usually have two limitations: images may lose partial information, such as depths of surface defects, and their precision is vulnerable to many factors, such as the inspection angle, light, color, noise, etc. Given that a three-dimensional (3D) point cloud can precisely represent the multidimensional structure of surface defects, we aim to detect and classify surface defects using a 3D point cloud. This has two major challenges: (i) the defects are often sparsely distributed over the surface, which makes their features prone to be hidden by the normal surface and (ii) different permutations and transformations of 3D point cloud may represent the same surface, so the proposed model needs to be permutation and transformation invariant. In this paper, a two-step surface defect identification approach is developed to investigate the defects’ patterns in 3D point cloud data. The proposed approach consists of an unsupervised method for defect detection and a multi-view deep learning model for defect classification, which can keep track of the features from both defective and non-defective regions. We prove that the proposed approach is invariant to different permutations and transformations. Two case studies are conducted for defect identification on the surfaces of synthetic aircraft fuselage and the real precast concrete specimen, respectively. The results show that our approach receives the best defect detection and classification accuracy compared with other benchmark methods.
An Interactive Rehabilitation Mechanism Design System for Kinematic and Kinetostatic Synthesis With Expandable Solution Space
Authors: Li Xiangyun , Shu Xin , Chen Peng , Yu Xi , Li Kang 
Published: October 2022

Abstract
Compared to manual therapy, robot therapy can provide more intensive and accurate rehabilitation training. However, most current devices are built on bulky and complex multi-degree-of-freedom (multi-DOF) mechanisms. Recently, 1-DOF mechanisms have gained popularity due to their portability and simplicity. Existing synthesis methods for 1-DOF mechanisms focus primarily on computing the optimal mechanism dimensions such that kinematic error between the task and the mechanism output is minimized. In cases where the kinematically feasible solutions become impractical under engineering circumstances, designers may need a handle to intervene in the synthesis process; moreover, the force interactions between the mechanism and users should also be considered to encourage the active participation of users for effective physical recovery. In this paper, we combine kinematic and kinetostatic synthesis to develop an interactive rehabilitation mechanism design system, taking into account task specifications on rehabilitation motion and gravity balancing. To enable interactive design, users are invited to manage the task movement via kinematic tolerance-oriented variation, thus providing the flexibility to address practical constraints. To compensate the gravity, torsional springs are attached to the actuated joints of the mechanism and human limb, and designed based on the principle of static balancing. For presenting a systematic, general, and defect-free design methodology for 1-DOF rehabilitation mechanisms, the synthesis model is formulated in a Fourier way to better accommodate different mechanism types and continuous limb motion. Examples of the upper- and lower-limb rehabilitation mechanism design are given in the end to demonstrate the validity of the proposed method.
Effect of social prescribing link workers on health outcomes and costs for adults in primary care and community settings: a systematic review
Authors: Kiely Bridget , Croke Aisling , O'Shea Muireann , Boland Fiona , O'Shea Eamon , Connolly Deirdre , Smith Susan M 
Published: October 2022

ObjectivesTo establish the evidence base for the effects on health outcomes and costs of social prescribing link workers (non-health or social care professionals who connect people to community resources) for people in community settings focusing on people experiencing multimorbidity and social deprivation.DesignSystematic review and narrative synthesis using the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach.Data sourcesCochrane Database, Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, EU Clinical Trials Register, CINAHL, Embase, Global Health, PubMed/MEDLINE, PsycInfo, LILACS, Web of Science and grey literature were searched up to 31 July 2021. A forward citation search was completed on 9 June 2022.Eligibility criteriaControlled trials meeting the Cochrane Effectiveness of Practice and Organisation of Care (EPOC) guidance on eligible study designs assessing the effect of social prescribing link workers for adults in community settings on any outcomes. No language restrictions were applied.Data extraction and synthesisTwo independent reviewers extracted data, evaluated study quality using the Cochrane EPOC risk of bias tool and judged certainty of the evidence. Results were synthesised narratively.ResultsEight studies (n=6500 participants), with five randomised controlled trials at low risk of bias and three controlled before–after studies at high risk of bias, were included. Four included participants experiencing multimorbidity and social deprivation. Four (n=2186) reported no impact on health-related quality of life (HRQoL). Four (n=1924) reported mental health outcomes with three reporting no impact. Two US studies found improved ratings of high-quality care and reduced hospitalisations for people with multimorbidity experiencing deprivation. No cost-effectiveness analyses were identified. The certainty of the evidence was low or very low.ConclusionsThere is an absence of evidence for social prescribing link workers. Policymakers should note this and support evaluation of current programmes before mainstreaming.PROSPERO registration numberCRD42019134737.
Apparent Digestibility Coefficients of Black Soldier Fly (Hermetia illucens), Yellow Mealworm (Tenebrio molitor), and Blue Bottle Fly (Calliphora vicina) Insects for Juvenile African Catfish Hybrids (Clarias gariepinus × Heterobranchus longifilis)
Authors: Sándor Zsuzsanna J. , Banjac Vojislav , Vidosavljević Strahinja , Káldy Jenő , Egessa Robert , Lengyel-Kónya Éva , Tömösközi-Farkas Rita , Zalán Zsolt , Adányi Nóra , Libisch Balázs , Biró Janka 
Published: October 2022

A digestibility trial was conducted with African catfish hybrid juveniles in order to determine the apparent digestibility coefficients (ADCs) of different nutrients. The experimental diets contained defatted black soldier fly (BSL), yellow mealworm (MW), or fully fat blue bottle fly (BBF) meals, in a 70 : 30 ratio between the control diet and the tested insect meals. The indirect method for the digestibility study was performed using 0.1% yttrium oxide as an inert marker. Fish juveniles of

217.4
±
9.5

g

initial weight were distributed in 1 m3 tanks (75 fish/tank) of a recirculating aquaculture system (RAS), in triplicates, and fed until satiation for 18 days. The average final weight of the fish was

346
±
35.8

g

. The ADCs of the dry matter, protein, lipid, chitin, ash, phosphorus, amino acids, fatty acids, and gross energy for the test ingredients and diets were calculated. A six-month storage test was carried out to evaluate the shelf life of the experimental diets, while the peroxidation and microbiological status of the diets were also assessed. The ADC values of the test diets differed significantly (

p
<
0.001

) compared to those of the control for most of the nutrients. Altogether, the BSL diet was significantly more digestible for protein, fat, ash, and phosphorus than the control diet but less digestible for essential amino acids. Significant differences were found between the ADCs of the different insect meals evaluated (

p
<
0.001

) for practically all nutritional fractions analyzed. The African catfish hybrids were able to digest BSL and BBF more efficiently than MW, and the calculated ADC values agreed with those of other fish species. The lower ADCs of the tested MW meal correlated (

p
<
0.05

) with the markedly higher acid detergent fiber (ADF) levels present in the MW meal and MW diet. Microbiological evaluation of the feeds revealed that mesophilic aerobic bacteria in the BSL feed were 2–3 orders of magnitude more abundant than those in the other diets and their numbers significantly increased during storage. Overall, BSL and BBF proved to be potential feed ingredients for African catfish juveniles and the shelf life of the produced diets with 30% inclusion of insect meal retained the required quality during a six-month period of storage.
Transurethral Renal Pelvic Denervation: A Feasibility Trial in Patients with Uncontrolled Hypertension
Authors: Hering Dagmara , Nikoleishvili David , Imedadze Avtandil , Dughashvili Gvantsa , Klimiashvili Zurab , Bekaia Eter , Shengelia Tamar , Kobalava Mamuka , Goguadze Otar , Emukhvari Tamar , Druker Vitaly , Sackner-Bernstein Jonathan , Weber Michael A. 
Published: October 2022

Background:
Endovascular renal denervation reduces blood pressure (BP). We explored an alternative approach to renal denervation using radiofrequency energy delivered across the renal pelvis utilizing the natural orifice of the urethra and the ureters.

Methods:
This open-label, single-arm feasibility study enrolled patients with uncontrolled hypertension despite antihypertensive drug therapy. The primary effectiveness endpoint was the change in ambulatory daytime systolic BP (SBP) 2 months following renal pelvic denervation.

Results:

The 18 patients (mean age 56±12 years) enrolled were taking an average of 2.7 antihypertensive drugs daily. Renal pelvic denervation reduced mean daytime SBP by 19.4 mm Hg (95% CI, −24.9 to −14.0,
P
<0.001) from its baseline of 148.4±8.7 mm Hg. Mean nighttime (−21.4 mm Hg [95% CI, −29.5 to −13.3]) and 24-hour (−20.3 mm Hg [95% CI, −26.2 to −14.5]) SBP each fell significantly (
P
<0.001) as did the corresponding diastolic BPs (
P
<0.001).

Office SBP decreased from 156.5±12.3 mm Hg by 22.4 mm Hg (95% CI, −31.5 to −13.3,
P
<0.001) by 2 months. Office SBP decreased over time (
P
=0.001 by linear trend test) starting by day 1 with a decrease of 8.3 mm Hg (95% CI, −16.9 to 0.3,
P
=0.057).

There were no serious adverse events. Mild transitory back pain followed the procedure. Serum creatinine decreased by 0.08 mg/dL (
P
=0.02) and estimated glomerular filtration rate increased by 7.2 mL/min/1.73m
2
(
P
=0.03) 2 months following ablation procedure.

Conclusions:
Based on these initial findings, a well-powered, sham-controlled trial of renal pelvic denervation to more fully establish its safety and effectiveness is now justified in patients with uncontrolled hypertension despite drug therapy.

Registration:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT05440513.
Les traditions céramiques du mégalithisme du Sénégal et de Gambie : une nouvelle périodisation pour l’Afrique de l’Ouest aux Ier et IIe millénaires de notre ère
Authors: Delvoye Adrien 
Published: October 2022

Résumé
Cet article présente les fondements, la construction et les résultats d’un nouveau modèle de périodisation des productions céramiques provenant des sites mégalithiques du Sénégal et de Gambie (8e-16e siècles). Pour la première fois dans cette région, cette périodisation est basée sur des contextes stratigraphiques soigneusement renseignés, obtenus sur la nécropole de Wanar (Sénégal). Le croisement des approches typologiques et technologiques révèle différentes productions, reflets de traditions céramiques et de groupes artisanaux distincts. À Wanar, la succession de ces productions aux caractères morpho-fonctionnels spécifiques a pu être corrélée avec l’émergence de styles architecturaux particuliers. Cette périodisation offre également une lecture renouvelée des corpus céramiques issus de fouilles anciennes. Elle interroge par ailleurs le statut des productions céramiques et des sites, en distinguant les vestiges antérieurs à l’érection des architectures monumentales de ceux participant pleinement à leur fonctionnement rituel. Cette recherche permet finalement d’entamer une réflexion sur la place des traditions céramiques sénégambiennes au sein de l’Afrique de l’Ouest médiévale.
This article aims to detail the construction and results of a new periodization of ceramic productions from megalithic sites in Senegal and The Gambia (8th-16th centuries CE). For the first time there, this model is based on carefully documented stratigraphic contexts obtained on the necropolis of Wanar (Senegal). The intersection of typological and technological approaches reveals different productions, reflections of ceramic traditions, and distinct craft groups. In Wanar, the succession of these productions with specific morpho-functional characters could be correlated with the emergence of particular architectural styles. This periodization also integrates materials from previous excavations and thus offers a renewed reading of it. The distinction between ceramic vestiges anterior to the erection of monumental architectures and others fully participating in their ritual functioning leads to question both the status of ceramic productions and sites. This research finally contributes to integrating Senegambian pottery production into the broader context of medieval West Africa.
Viabundus: Map of Premodern European Transport and Mobility
Authors: Holterman Bart , A.B. Maartje , Andersen Kasper H. , Dengg Maria C. , Petersen Niels 
Published: October 2022

Abstract
Viabundus is an open access online interactive map and database on roads and mobility in premodern northern and central Europe. The database covers the period 1350–1650. It is designed as a network model and includes digital reconstructions of long-distance land routes and inland waterways as well as a database with information about settlements, towns, toll stations, staple markets, fairs, bridges, ferries, harbours and shipping locks. This makes it possible to use the dataset for advanced analyses with methods of gis and network analysis. With the web application and downloadable dataset, the Viabundus project has created a tool for the analysis of premodern mobility for economic (transaction costs) and all other kinds of historical study involving movement of people and goods.
Multifunctionality of Epistemic Stance Markers: Variation across Disciplines and Speaker Roles in Classroom Discourse
Authors: Caprario Marcella 
Published: October 2022

Abstract
This study investigated the communicative functions of ‘I think’ and ‘I guess’ in classroom discourse and intra-register variation in their use. Building on research into the multifunctionality of epistemic stance markers, a coding scheme was developed and iteratively applied to a corpus, revealing five macro functions: epistemic stance, softening, personal perspective, discourse organizing, and deciding in real time. The frequency of each macro function differed between the two markers, as did the observed subfunctions. Statistical analyses comparing instructors and students in three disciplines indicated intra-register variation, linked to situational differences. ‘I guess’ was most frequent in student language, and ‘I think’ was most frequent in the humanities. Different patterns were also noted in the use of certain communicative functions. The results suggest the importance of accounting for register variation when describing epistemic stance markers.
De Pan-Orthodoxe Conferentie van Rhodos 26-29 September 1963
Authors: Aarns A.A W. 
Published: October 2022

La conférence panorthodoxe de Rhodes du 26 au 29 septembre 1963
Au cours de deux années l’Orthodoxie à réussi à convoquer deux fois une conférence panorthodoxe à Rhodes. La première du 24 septembre jusqu’au 2 octobre 1961, de nature plutôt préparatoire et explorateur, la seconde du 26 au 30 septembre 1963, convoquée par le patriarche oecuménique Athénagoras à la suite de l’invitation de Rome à l’Eglise orthodoxe au sujet de l’envoi d’observateurs à la deuxiéme session du concile du Vatican. La conférence à examiné en général la question des relations entre l’Eglise orthodoxe et celle de Rome et elle à discuté de la manière la plus convenable pour l’orthodoxie de mettre à sa disposition tous les moyens positifs au service de la réconciliation entre les deux Eglises, d’accord avec les décisions de la première conférence. Au sujet de l’envoi d’observateurs on décida que chacune des Eglises orthodoxes agirait librement. Pour le second point, la proposition du patriarche oecuménique de commencer un dialogue entre l’Eglise orthodoxe et l’Eglise catholique romaine sur pied d’égalité fut reçue à l’unanimité. Malgré l’abstention de l’Eglise de Grèce et l’absence des Eglises de Finlande, d’Albanie, de Géorgie et de Pologne la conférence fut un grand succès pour la cause de l’unité, pour l’orthodoxie et surtout pour le patriarcat oecuménique, dont la prudente audace à réussi la réalisation et l’a fait aboutir à la décision, que même l’Eglise de Grêce finit par ratifier, malgré sa révolte contre la conférence à la suite de difficultés internes.
Montreal 1963
Authors: van Montfoort A.A. E. 
Published: October 2022

Montreal 1963
L’auteur donne un compte-rendu des réunions qui, clans le cadre de la Conférence Mondiale de „Foi et Constitution”, se sont tenues à Montreal au mois de juillet 1963. La première fut la consultation entre des théologiens orthodoxes et non-orthodoxes, ayant comme but de fixer une liste de sujets, dont l’étude serait d’un grand avantage pour le Mouvement Oecuménique. Comme tels furent fixés: 1) une étude critique et historique de l’evolution de la Christologie dans l’âge patristique; 2) la Pneumatologie, y compris la doctrine de la grâce; 3) continuité et autorité clans l’Eglise avec une mention spéciale de la signification des conciles oecuméniques.
Puis l’article donne un asperçu général des réunions de la commission du 24 juillet, du comité directeur des 26 et 27 juillet, et de la Conférence Mondiale de Foi et Constitution du 12-26 juillet.