bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mesoporous NiCo2S4 nanoflakes as an efficient and durable electrocatalyst for non-enzymatic detection of cholesterol
Authors: Rabbani Syeda Sughra , Nisar Amjad , Zafar Amina , Liu Yanguo , Sun Hongyu , Karim Shafqat , Hussain Shafqat , Shah Atta Ullah , Hussain Syed Zahid , Mehboob Nasir , Yu Yanlong , Ahmad Mashkoor 
Published: June 2022

Abstract
The detection of cholesterol is very crucial in clinical diagnosis for rapid and accurate monitoring of multiple disease-biomarkers. There is a great need for construction of a highly reliable and stable electrocatalyst for the efficient detection of cholesterol. In this work, mesoporous NiCo2S4 nanoflakes of enhanced electrochemical properties are prepared through a facile hydrothermal approach. The developed nanoflakes modified nickel foam electrode exhibits outstanding electrocatalytic properties for the detection of cholesterol with high selectivity. The electrode displays excellent sensitivity of 8623.6 μA mM−1 cm−2, in the wide linear range from 0.01 to 0.25 mM with a low detection limit of 0.01 μM. In addition, NiCo2S4 structure reveals good thermal stability and reproducibility over a period of 8 weeks. Moreover, the nanoflakes show good response for detection of cholesterol in real samples. Our results demonstrate the potential use of NiCo2S4 as a catalyst for the development of cost-effective electrochemical sensors for medical and industrial applications.
Optimal analytical and numerical approximations to the (un)forced (un)damped parametric pendulum oscillator
Authors: Alyousef Haifa A , Alharthi M R , Salas Alvaro H , El-Tantawy S A 
Published: June 2022

Abstract
The (un)forced (un)damped parametric pendulum oscillator (PPO) is analyzed analytically and numerically using some simple, effective, and more accurate techniques. In the first technique, the ansatz method is employed for analyzing the unforced damped PPO and for deriving some optimal and accurate analytical approximations in the form of angular Mathieu functions. In the second approach, some approximations to (un)forced damped PPO are obtained in the form of trigonometric functions using the ansatz method. In the third approach, He’s frequency-amplitude principle is applied for deriving some approximations to the (un)damped PPO. In the forth approach, He’s homotopy technique is employed for analyzing the forced (un)damped PPO numerically. In the fifth approach, the p-solution Method, which is constructed based on Krylov–Bogoliúbov Mitropolsky method, is introduced for deriving an approximation to the forced damped PPO. In the final approach, the hybrid Padé-finite difference method is carried out for analyzing the damped PPO numerically. All proposed techniques are compared to the fourth-order Runge–Kutta (RK4) numerical solution. Moreover, the global maximum residual distance error is estimated for checking the accuracy of the obtained approximations. The proposed methodologies and approximations can help many researchers in studying and investigating several nonlinear phenomena related to the oscillations that can arise in various branches of science, e.g. waves and oscillations in plasma physics.
Scheme Design of Xenon Composite Over-wrapped Pressure Vessel for Electric Propulsion System
Authors: YU Bin , ZHAO Lei , ZHAO Jipeng , MA Tianju , GU Sendong , YANG Wenbo , LI Lifeng 
Published: June 2022

Abstract
The composite over-wrapped pressure vessel (COPV), which were made by ultra-thin metal liner and high strength carbon fiber reinforced plastic (CFRP), has high performance factor (PV/W). COPV were widely used in electric propulsion system (EPS) of space system. ANSI/AIAA S-081-2000 is a general standard for pressure vessel of aerospace field at home and abroad, it specified the design elements, references, specifications, requirements in detail. The materials selection of liner, CFRP and skirt are introduced respectively. The design contents of liner and CFRP are explained. The liner is designed in terms of equal strength principle and the composite structure was designed in term of hoop fiber layers and spiral fiber layers alternately over-wrapped. The skirt is composite structure, with X-X carbon fiber over-wrapped the TC4 titanium alloy. The titanium liner thickness is 0.8mm, Cycle life is at last 100 times when the liner thick is ultra-thin. The safe life was designed, including stress-rupture life and low cycle fatigue-life. The leak before burst (LBB)safe failure mode was analyzed. The results show that the structure design meets the technical requirements.
The Design and Development of the Automatic Trigger Device for the High-Speed Photography
Authors: Hou Shengchao 
Published: June 2022

Abstract
At present, there is a problem, which is inconvenient for people to record structure failure data, in some experimental process of special equipment. Focusing on the trigger method of high speed photography recording in the component strength experiment of special equipment, and choosing the feature of vibration in the situation that the strength of specimen is failure, we design two schemes, which are integration vibration switch basing on velocity and voltage comparator vibration switch basing on acceleration, according the design ideas that include analysis, design, specification and verification. Through the verification of the experiment, the method of voltage comparator vibration switch basing on acceleration is feasible, and the successful rate of auto-trigger can reach 100 percent in the situation of usual strength failure. The device has fine trigger stability and accuracy, can effectively solve the problem that manipulation has low rate of successful operation and reliability.
Structural Design of 209 Type Fully Open Lid Mould
Authors: Tan Zhihang , Tan Fenfang , Xu Kai , Fan Lanlan , Xiong Can , Yang Junsheng , Chen Yinlei 
Published: June 2022

Abstract
In this work SolidWorks software was used to design the mold structure of model 209 all-open easy open lid. Firstly, the high-speed forming process of basic lid and finished lid in model 209 all-open easy open lid was analyzed. Then the mold design for its auxiliary engraving line and stop-slip point was carried out, and the convex and concave die of the first station was theoretically analyzed. Finally, the 3D mold structure design for the basic cover, finished cover and pull ring was carried out, and 209 type fully open type easy open cover general assembly drawing was designed. Some practical problems such as interference and position relation ware solved in die design. It has certain guiding significance to the design of easy opening lid.
Rethinking User Experience Design: Sustainability in the Context of the User Centered Innovation Process in Power Tool Design
Authors: Grobelnik Manuel , Cakir Feyyaz , Friedmann Daniel-Philipp , Maul Ludwig 
Published: June 2022

Abstract
Sustainability is becoming increasingly important in product development: both for the manufacturing companies and for the users, who are increasingly questioning the product and its origin. While sustainability is recognised as a strategic factor in many companies, the focus in the operational process is still mainly on desirability, feasibility and profitability, while sustainability is not firmly anchored in the various process steps and thus not effectively operationalised. The aim of this research work is to develop a process that integrates sustainability as a common thread throughout the product development of power tools. For this purpose, a case study at Bosch Power Tools with 10 guideline-supported expert interviews and a workshop with 8 experts shows what requirements are placed on such a process and what such a process should ideally look like. The result is a multi-stage model that integrates the relevant sustainability aspects and thus makes them comprehensible and measurable for practitioners in innovation, design, and product development in medium sized and large organisations.
Dynamic Modeling and Simulation Analysis of Non-explosive Separation Device
Authors: Li Xuemei , Sun Beibei 
Published: June 2022

Abstract
In order to ensure reliable connection and separation between satellites and the launch vehicles, a dynamic modeling method of a certain type of non-explosive separation device based on contact theory is proposed to carry out more accurate results in this paper. After analysis on the actuation principle of the non-explosive separation device, the source of impact response is clarified. Then the contact model is established based on the contact theory and the dynamic simulation model is established. The dynamic simulation results show that the shock acceleration of housing is no more than 300g, it is consistent with the experimental results performed by other workers. The simulation model can be utilized for the design and validation of the non-explosive separation device to provide a reliable basis for subsequent optimization.
Pressure Distribution Prediction of Supercritical Airfoils at Multiple Flight Conditions Using Deep Learning Approach
Authors: MA Tuliang , XIE Hairun , WANG Jing 
Published: June 2022

Abstract
Supercritical airfoils are commonly found in modern civil airplanes. Effective access to pressure distribution around an airfoil under various flight situations is vital for enhancing the quality of supercritical airfoils. With the rapid development of deep learning, the rise of neural networks has provided new powerful tools for obtaining pressure distribution quickly. This paper proposed a deep learning based model to predict the surface pressure distribution around a supercritical airfoil under multiple flight conditions. The airfoil geometry parameters and various flight conditions are taken as input, and the corresponding surface pressure distributions are taken as output. The statistical results show that the proposed method is accurate and generalized in predicting pressure distributions around supercritical airfoils. Our method, in particular, achieves accurate prediction results over the double shock or strong shock area, demonstrating its superiority in handling complex flows.
Research on Parametric Design and Feature Modeling of Freight Ropeway Running Car of Transmission Line
Authors: MinJie ZHU , JianHua LI , KeYang XU , Chen LIU , Fei WANG 
Published: June 2022

Abstract
To improve the freight ropeway components design efficiency, the component structure design is carried out for the components of freight ropeway of transmission line using 3d design software by using parameter modification method. The parametric design and feature modeling of freight ropeway running car is proposed to realize components modelling, and analyse its force conditions to meet the strength requirements. The proposed method can improve the efficiency of freight ropeway structural design.
Integrated Frame Topology Optimization Design of Small Quadrotor UAV
Authors: Qu Jiaqi , Dong Yihao , Gu Xuechen , He Shaoming 
Published: June 2022

Abstract
In recent years, the development of UAV (Unmanned Aerial Vehicle) is rapid, but the development of structural design is slow, and the rack designed according to the experience of engineers still has great redundancy. With the rapid development of topology optimization and additive manufacturing, topology optimization design of integrated rack based on additive manufacturing is carried out. In the design process, manufacturing constraints are added and a variety of typical conditions to obtain the final optimization structure are considered. The influence of human empirical factors on the fuselage structure design is reduced scientifically and effectively by using this method. And the lightweight, topological and integrated design of the quadrotor frame is realized.
Methodological approach to assessing environmental risk (health risk) from air pollution in the Baikal region in a changing climate
Authors: Makosko A A , Matesheva A V 
Published: June 2022

Abstract
The methodological approach to assessing the environmental risk (health risk) from atmospheric pollution in the Baikal region taking into account the changing climate was formulated. It is based on the US EPA's health risk assessment methodology and impurity concentration estimates by solving the adjoint equation for impurities transport and diffusion. The dynamics of health risk for the population of Irkutsk from atmospheric pollution PM10, PM2.5 due to emissions from possible sources located both in the Baikal region and beyond including sources of transboundary pollution in 1980-2050 under various scenarios of climate change was researched. A tendency for a moderate decrease in the considered risk over the past several decades was shown. In the forecast period until 2050, under both climate scenarios, significant changes in the risk were not noted. The spatio-temporal dynamics of the areas of PM10, PM2.5 sources location that create the increased health risk in relation to Irkutsk was studied. The results indicate the moderate narrowing of the increased risk zone for Irkutsk in the first half of the 21st century. In the period until 2050, the main impact on the population health in the Irkutsk area from emission sources located in the southwest, south and southeast is expected. In case of transboundary pollution, the main danger from sources in Kazakhstan, Mongolia, and China is expected. The results are important to develop proposals for ensuring safety for public health, developing health care and planning environmental protection measures in the Baikal and neighboring regions.
Investigation of wind shear structure and turbulence characteristics in a warm front cloud system using a research aircraft
Authors: Volkov V V , Strunin A M , Kirin D V , Kolokutin G E , Strunin M A 
Published: June 2022

Abstract
The manuscript presents the results of study vertical and horizontal wind shears, the spectral characteristics of turbulence in the warm front cloud system with using the Yak-42D aircraft-laboratory. Within the As-Cs clouds at altitudes of 3 - 8 km, vertical wind shear increased sharply to 1.5 ms-1 per 100 m. At altitudes of 8 - 9 km, in the jet stream zone, vertical wind shear increased up to significant values of 3.0 ms-1 per 100 m. The maximum horizontal wind shear of 0.3 ms-1 per km was reached in As-Ns clouds at altitudes of 2 - 4 km. Anisotropy of turbulence with a predominance of horizontal wind fluctuations was observed in the stable layer at the altitude of 6000 m. The normalized spectra of the wind speed fluctuations in the lower part of the cloud system (at an altitude of about 3 km) corresponded to the stable layers of the atmosphere. The maximum value of 0.8 at the coherence spectra between the temperature and the vertical wind speed fluctuations was observed at the scales of 1200 m. It is noted that a solid Cs-As-Ns cloud system could be divided into sub-layers, depending on structure of wind shear and turbulence.
On the ratio of the components of the atmospheric vertical electric current density in fair weather
Authors: Anisimov S V , Galichenko S V , Prokhorchuk A A , Aphinogenov K V 
Published: June 2022

Abstract
This work presents the results of ground-based and tethered balloon observations of altitude profiles of the components of the atmospheric vertical electric current density. The magnitude of the conduction current density was observed in the range 0.2 - 2 pAm−2. The ratio of the negative to positive component of the conduction current density averaged 1.6 outside the layer, where their dependence on the height was noticeable. In the framework of developed numerical model with reasonable values of the parameters it is found that the ratio of the convection current density to the density of the total vertical atmospheric electric current in the atmospheric boundary layer mainly falls in the range 0.2 - 0.6 and tends to increase under strong convection and low electrical conductivity. An exponential parameterization of the dependence of the electromotive force on the ground-level electrical conductivity is proposed.
Aleurite particle concentration profiles in the surface layer of the atmosphere on desertificated areas
Authors: Gushchin R A , Gorchakov G I , Karpov A V 
Published: June 2022

Abstract
The large particle mass flux profile measurement at heights from 0.125 to 16 m and parameters of the size distribution function received by O.E. Semenov on the desertificated areas in the Aral region were analyzed. The technique has been worked out for the large particle height profile characteristic retrieving. The aleurite particle number concentration profiles with sizes less than 50, 73 and 100 μm and sand particle concentration have been retrieved. Power-law approximations of the vertical aleurite and sand particles concentrations profiles are proposed.
Application of wavelet analysis methods to study the climate of the Arctic region
Authors: Solovyev DA , Nefedova LV 
Published: June 2022

Abstract
This paper provides an assessment of the possibilities and advantages of using wavelet analysis methods in the study of regional mechanisms of climate formation in the Arctic region by analyzing the relationship between the values of the air temperature anomalies at the Earth's surface and the North Atlantic Oscillation index. It is shown that the methods of wavelet analysis of climatic indices have certain advantages for identifying cyclical changes in climatic characteristics on local time scales and allow an in-depth spectral assessment. The conducted wavelet analysis of the NAO and SAT index (1950-2020) made it possible to estimate the previously known natural quasi-cyclic oscillations with a typical period of 7-15 years and other dominant components of their spectrum.
Ultra-Processed Foods Consumption Increases the Risk of Hypertension in Adults: A Systematic Review and Meta-Analysis
Authors: Wang Mei , Du Xinyi , Huang Wei , Xu Yong 
Published: June 2022

AbstractBackgroundEffect of ultra-processed foods (UPFs) consumption on health has attracted widespread attention in recent years. However, the relationship between UPFs consumption and hypertension is unclear. This meta-analysis was conducted to analyze the above association.MethodsWe systematically searched PubMed, Embase, and Cochrane Library for all relevant studies published up to 31 January 2022 without language limitation. The random-effects model was selected to pool the effect sizes and 95% confidence intervals (CIs).ResultsNine observational studies involving 111,594 participants were included. Results from this meta-analysis showed that higher UPFs consumption significantly increased the risk of hypertension (odds ratio: 1.23; 95% CI: 1.11, 1.37; P = 0.034). Furthermore, analyses were performed based on gender, study design, exposure assessment, outcome assessment, body mass index, energy intake, and physical activity, which suggested that the results remained statistically significant.ConclusionsOur findings suggested that UPFs might have detrimental effects on the incidence of hypertension in the general population. Although current evidence is limited, it cannot be denied that reducing consumption of UPFs may contribute to decrease the risk of chronic noncommunicable diseases.
Proteomic analysis of nascent polypeptide chains that potentially induce translational pausing during elongation
Authors: Shimohata Nobuyuki , Harada Yudai , Hayano Toshiya 
Published: June 2022

ABSTRACT
Currently, proteins equipped with “ribosomal arrest peptides” (RAPs) that regulate the expression of downstream genes and their own activity by pausing their own translation during elongation are extensively studied. However, studies focusing on RAP have been conducted primarily in prokaryotic cells; studies on eukaryotic cells, especially mammalian cells, are limited. In the present study, we comprehensively examined translationally arrested nascent polypeptides to gain novel insights into RAPs in mammalian cells. Cetyltrimethylammonium bromide was used to obtain nascent polypeptide chains that were translationally arrested during translation elongation. After proteomic analysis, additional screening by discriminating according to amino acid residues at the C-terminal end revealed several novel RAP candidates. Our method can be applied for comprehensive RAP studies in mammalian cells.
Glutamate can act as a signaling molecule in mouse preimplantation embryos
Authors: Špirková Alexandra , Kovaříková Veronika , Šefčíková Zuzana , Pisko Jozef , Kšiňanová Martina , Koppel Juraj , Fabian Dušan , Čikoš Štefan 
Published: June 2022

AbstractFree amino acids are present in the natural environment of the preimplantation embryo, and their availability can influence early embryo development. Glutamic acid is one of the amino acids with the highest concentrations in female reproductive fluids, and we investigated whether glutamic acid/glutamate can affect preimplantation embryo development by acting through cell membrane receptors. Using reverse transcription-polymerase chain reaction, we detected 15 ionotropic glutamate receptor transcripts and 8 metabotropic glutamate receptor transcripts in mouse ovulated oocytes and/or in vivo developed blastocysts. Using immunohistochemistry, we detected the expression of two α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor subunits, three kainate receptor subunits, and member 5 metabotropic glutamate receptor protein in blastocysts. Extracellular concentrations of glutamic acid starting at 5 mM impaired mouse blastocyst development, and this fact may be of great practical importance since glutamic acid and its salts (mainly monosodium glutamate) are widely used as food additives. Experiments with glutamate receptor agonists (in combination with gene expression analysis) revealed that specific AMPA receptors (formed from glutamate receptor, ionotropic, AMPA3 [GRIA3] and/or glutamate receptor, ionotropic, AMPA4 [GRIA4] subunits), kainate receptors (formed from glutamate receptor, ionotropic, kainate 3 [GRIK3] and glutamate receptor, ionotropic, kainate 4 [GRIK4] or glutamate receptor, ionotropic, kainate 5 [GRIK5] subunits), and member 5 metabotropic glutamate receptor (GRM5) were involved in this effect. The glutamic acid-induced effects were prevented or reduced by pretreatment of blastocysts with AMPA, kainate, and GRM5 receptor antagonists, further confirming the involvement of these receptor types. Our results show that glutamic acid can act as a signaling molecule in preimplantation embryos, exerting its effects through the activation of cell membrane receptors.
Endophytic fungi and their bioactive secondary metabolites in medicinal leguminosae plants: nearly untapped medical resources
Authors: Zhou Zhong-Ya , Liu Xi , Cui Jin-Long , Wang Jun-Hong , Wang Meng-Liang , Zhang Gang 
Published: June 2022

Abstract
There are many species of Chinese traditional leguminosae family plants that are well known for their medicinal applications, such as Astragalus membranaceus, Catsia tora, Glycyrrhiza uralensis, Sophora flavescens and Albacia acacia. Their unique bioactive composition and internal phenological environment contribute to the formation of specific and unique endophytic fungal communities, which are important resources for new compounds used in a variety of pharmacological activities. Nonetheless, they have not been systematically studied. In the last decade, nearly 64 genera and thousands of species of endophytic fungi have been discovered from leguminosae plants, as well as 138 secondary metabolites (with 34 new compounds) including flavonoid, alkaloids, phenol, anthraquinone, macrolide, terpenoid, phytohormone and many more. These were shown to have diverse applications and benefits, such as antibacterial, antitumor, antioxidative, immunoregulatory and neuroprotective properties. Here, we provide a summarized overview with the aim of raising awareness of endophytic fungi from medicinal leguminosae plants and providing a comprehensive review of the discoveries of new natural products that may be of medicinal and pharmaceutical importance.