bluuebunny/crossref_metadata_2025_split huggingface dataset:
Silver Nanoparticles: Synthesis in Newly Formed Ternary Deep Eutectic
Solvent Media, Characterization and their Antifungal Activity
Authors: D Ilangeswaran , K Sarjuna 
Published: August 2022

Background:
When halide salts and hydrogen bond donors are combined, they produce Deep Eutectic Solvents, which have a lower freezing/melting point than the individual components. At room temperature, they have emerged as viable alternatives to ionic liquids. The wonderful features of deep eutectic solvents such as humidity tolerance, high-temperature stability, low cost, non-hazardous, reusable, and recyclable nature, allow them to replace ionic liquids.

Objective:
To prepare two newer Ternary Deep Eutectic Solvents using Malonic acid - Glucose – Glutamine and Malonic acid - Fructose – Glutamine. Using the prepared ternary deep eutectic solvents, to synthesize silver nanoparticles and study the antifungal behavior.

Methods:
The ternary deep eutectic solvents were prepared by the evaporation method in water and subjected to measure the properties such as density, pH, conductivity, viscosity, and absorption frequencies of Fourier Transform Infrared Spectroscopy. The prepared deep eutectic solvents are used for the synthesis of Silver Nanoparticles by the chemical reduction method in presence of Hydrazine Hydrate as a reducing agent and sodium hydroxide as a stabilizing agent. The synthesized nanoparticles are characterized by UV-Visible Spectroscopy, Fourier Transform Infrared Spectroscopy, X-ray diffraction, scanning electron microscopy, and energy dispersive X-ray analysis techniques.

Results:
The characteristic absorption peak of UV-Visible Spectroscopy shows that silver nanoparticles were formed. FTIR exposes the metallic and other bonding of the nanoparticles and the caping materials. From the XRD pattern, we found the crystalline and the images formed in the SEM are in the nanoscale. The average particle size of silver nanoparticles is 116.87nm and 26.61 nm.

Conclusion:
In our study, two types of novel ternary deep eutectic solvents were developed. They act as a better solvent media for the synthesis of silver nanoparticles and the synthesized nanoparticles show antifungal behaviors against some fungi.
Digital Health Competencies Among Health Care Professionals: Systematic Review
Authors: Longhini Jessica , Rossettini Giacomo , Palese Alvisa 
Published: August 2022

Background
Digitalization is not fully implemented in clinical practice, and several factors have been identified as possible barriers, including the competencies of health care professionals. However, no summary of the available evidence has been provided to date to depict digital health competencies that have been investigated among health care professionals, the tools used in assessing such competencies, and the effective interventions to improve them.

Objective
This review aims to summarize digital health competencies investigated to date and the tools used to assess them among health care professionals.

Methods
A systematic review based on the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) checklist was performed. The MEDLINE, Cumulative Index to Nursing and Allied Health Literature, PsycINFO, and Scopus databases were accessed up to September 4, 2021. Studies assessing digital health competencies with quantitative designs, targeting health care professionals, and written in English were included. The methodological quality of included studies was evaluated using the Joanna Briggs Institute tools.

Results
A total of 26 studies, published from 1999 to 2021, met the inclusion criteria, and the majority were cross sectional in design, while only 2 were experimental study designs. Most studies were assessed with moderate to low methodological quality; 4 categories and 9 subcategories of investigated digital health competencies have been identified. The most investigated category was “Self-rated competencies,” followed by “Psychological and emotional aspects toward digital technologies,” “Use of digital technologies,” and “Knowledge about digital technologies.” In 35% (9/26) of the studies, a previously validated tool was used to measure the competencies assessed, while others developed ad hoc questionnaires.

Conclusions
Mainly descriptive studies with issues regarding methodology quality have been produced to date investigating 4 main categories of digital health competencies mostly with nonvalidated tools. Competencies investigated might be considered while designing curricula for undergraduate, postgraduate, and continuing education processes, whereas the methodological lacks detected might be addressed with future research. There is a need to expand research on psychological and emotional elements and the ability to use digital technology to self-learn and teach others.

Trial Registration
PROSPERO International Prospective Register of Systematic Reviews CRD42021282775; https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=282775
Development and Validation of Indicators for Population Injury Surveillance in Hong Kong: Development and Usability Study
Authors: Tung Keith T S , Wong Rosa S , Ho Frederick K , Chan Ko Ling , Wong Wilfred H S , Leung Hugo , Leung Ming , Leung Gilberto K K , Chow Chun Bong , Ip Patrick 
Published: August 2022

Background
Injury is an increasingly pressing global health issue. An effective surveillance system is required to monitor the trends and burden of injuries.

Objective
This study aimed to identify a set of valid and context-specific injury indicators to facilitate the establishment of an injury surveillance program in Hong Kong.

Methods
This development of indicators adopted a multiphased modified Delphi research design. A literature search was conducted on academic databases using injury-related search terms in various combinations. A list of potential indicators was sent to a panel of experts from various backgrounds to rate the validity and context-specificity of these indicators. Local hospital data on the selected core indicators were used to examine their applicability in the context of Hong Kong.

Results
We reviewed 142 articles and identified 55 indicators, which were classified into 4 domains. On the basis of the ratings by the expert panel, 13 indicators were selected as core indicators because of their good validity and high relevance to the local context. Among these indicators, 10 were from the construct of health care service use, and 3 were from the construct of postdischarge outcomes. Regression analyses of local hospitalization data showed that the Hong Kong Safe Community certification status had no association with 5 core indicators (admission to intensive care unit, mortality rate, length of intensive care unit stay, need for a rehabilitation facility, and long-term behavioral and emotional outcomes), negative associations with 4 core indicators (operative intervention, infection rate, length of hospitalization, and disability-adjusted life years), and positive associations with the remaining 4 core indicators (attendance to accident and emergency department, discharge rate, suicide rate, and hospitalization rate after attending the accident and emergency department). These results confirmed the validity of the selected core indicators for the quantification of injury burden and evaluation of injury-related services, although some indicators may better measure the consequences of severe injuries.

Conclusions
This study developed a set of injury outcome indicators that would be useful for monitoring injury trends and burdens in Hong Kong.
Web-Based System to Capture Consistent and Complete Real-world Data of Physical Therapy Interventions Following Total Knee Replacement: Design and Evaluation Study
Authors: Franklin Patricia D , Oatis Carol A , Zheng Hua , Westby Marie D , Peter Wilfred , Laraque-Two Elk Jeremie , Rizk Joseph , Benbow Ellen , Li Wenjun 
Published: August 2022

Background
Electronic health records (EHRs) have the potential to facilitate consistent clinical data capture to support excellence in patient care, quality improvement, and knowledge generation. Despite widespread EHR use, the vision to transform health care system and its data to a "learning health care system" generating knowledge from real-world data is limited by the lack of consistent, structured clinical data.

Objective
The purpose of this paper was to demonstrate the design of a web-based structured clinical intervention data capture system and its evaluation in practice. The use case was ambulatory physical therapy (PT) treatment after total knee replacement (TKR), one of the most common and costly procedures today.

Methods
To identify the PT intervention type and intensity (or dose) used to treat patients with knee arthritis following TKR, an iterative user-centered design process refined an initial list of PT interventions generated during preliminary chart reviews. Input from practicing physical therapists and national and international experts refined and categorized the interventions. Next, a web-based, hierarchical structured system for intervention and intensity documentation was designed and deployed.

Results
The PT documentation system was implemented by 114 physical therapists agreeing to record all interventions at patient visits. Data for 161 patients with 2615 PT visits were entered by 83 physical therapists. No technical problems with data entry were reported, and data entry required less than 2 minutes per visit. A total of 42 (2%) interventions could not be categorized and were recorded using free text.

Conclusions
The use of user-centered design principles provides a road map for developing clinically feasible data capture systems that employ structured collection of uniform data for use by multiple practitioners across institutions to complement and augment existing EHRs. Secondarily, these data can be analyzed to define best practices and disseminate knowledge to practice.
Pengaruh Promosi Penjualan, Kenikmatan Berbelanja, Gaya Hidup Online Terhadap Impulsive Buying Masyarakat Muslim Millenial
Authors: Hayatun Nuri  
Published: August 2022

ABSTRAK
Adanya sistem jual beli online telah mendorong terjadinya pembelian impulsif Penelitian ini bertujuan untuk melihat pengaruh promosi penjualan, kenikmatan berbelanja dan gaya hidup online terhadap impulsive buying. Penelitian ini merupakan penelitian yang menggunakan pendekatan kuantitatif. Populasi dalam penelitian ini adalah generasi millennial yang berdomisili di Kota Banda Aceh pengguna aplikasi Shopee dengan penarikan sampel menjadi seratus responden. Jenis data dalam penelitian ini adalah data primer. Metode analisis data dalam penelitian ini menggunakan Structural Equation Modeling berbasis Partial Least Square (SEM-PLS) dengan bantuan aplikasi SmartPLS. Hasil penelitian ini menunjukkan bahwa promosi penjualan berhubungan positif dan signifikan terhadap kenikmatan berbelanja, kenikmatan berbelanja berhubungan positif dan signifikan terhadap impulsive buying. Gaya hidup online berhubungan positif dan signifikan terhadap kenikmatan berbelanja, kemudian promosi penjualan berhubungan positif dan signifikan terhadap impulsive buying dengan kenikmatan berbelanja sebagai variabel intervening, serta gaya hidup online juga berhubungan positif dan signifikan terhadap impulsive buying dengan kenikmatan berbelanja sebagai variabel intervening.
Kata Kunci: Promosi Penjualan, Kenikmatan Berbelanja, Gaya Hidup Online, SEM-PLS
PENGARUH PEMBERIAN DOSIS PUPUK UREA TERHADAP PERTUMBUHAN TANAMAN KANGKUNG DARAT (Ipomoea reptans Poir)
Authors: Nanda Vidasari  , Arif Sardi  , Rosmeri  
Published: August 2022

Kangkung merupakan salah satu jenis sayuran yang banyak ditemukan di Indonesia. Kandungan utama yang terdapat di dalam sayur kangkung adalah zat besi yang berguna untuk pertumbuhan dan kesehatan tubuh. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian berbagai dosis pupuk urea terhadap pertumbuhan tanaman kangkung dan mengetahui dosis pupuk urea yang tepat untuk pertumbuhan tanaman kangkung. Penelitian ini menggunakan metode Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan yaitu U0 (Kontrol) = 0 gr urea/ polybag, U1 = 0,5 gr urea/polybag, U2 = 1 gr urea/polybag, dan U3 = 1,5 gr urea/polybag dengan 4 kali pengulangan pada masing masing perlakuan. Hasil penelitian menunjukkan bahwa terdapat perbedaan yang nyata pada pertumbuhan tinggi tanaman dan jumlah helaian daun tanaman kangkung pada dosis U0 (Kontrol) dengan perlakuan U3. Untuk pengamatan pertumbuhan tanaman kangkung pada berbagai dosis pupuk urea didapatkan hasil pengukuran rata-rata pertumbuhan dapat dilihat pada 7 HST untuk perlakuan U0 (Kontrol) didapatkan tinggi batang yaitu 22,8 cm, dan helaian daun 45. Tinggi tanaman pada perlakuan U3 didapatkan hasil tinggi tanaman 21,6 cm dan jumlah helaian daun 50. Pengamatan pertumbuhan tanamn kangkung pada hari ke 29 HST didapatkan hasil rata – rata pertumbuhan tanamn kangkung, pada perlakuan U0 (Kontrol) didapatkan hasil tinggi tanaman 140,08 cm, dan jumlah helaian daun 83,75. Sedangkan pada perlakuan U3 didapatkan hasil rata – ratatinggi tanaman 182,025 cm dan jumlah helaian daun 102,5.
Kata kunci: tanaman kangkung, dosis, pupuk urea
POTENTIAL OF PHOSPHATE SOLUBILIZING BACTERIA FROM MANGROVE RHIZOSFER EFFECT PLANT GROWTH CORN (Zea mays)
Authors: Nanda Anastia  , Syafrina Sari Lubis  
Published: August 2022

Mangroves are an ecosystem that is inhabited by various kinds of organisms and microorganisms, one of which is phosphate solubilizing bacteria that can be isolated from the mangrove rhizosphere. This study used a completely randomized design (CRD) aimed to obtain isolates of Phosphate Solubilizing Bacteria (PSB) and test the potential for the growth of corn plants. There were 9 isolates of gram positive BPF and 1 gram negative BPF, all isolates were rod-shaped. The results of morphological and biochemical tests showed that 9 bacterial isolates are a group of the genus Bacillus with the code LSP 1, LSP 2, LSP 3, LSP 4, LSP 5, LSP 7, LSP 8, LSP 9, LSP 10 and the genus Pseudomonas with the code LSP 6 . Testing the value of the phosphate solubility index (IKF) found bacteria with the highest IKF values ​​of 33 mm and 23.25 with isolate codes LSP 1 and LSP 6. Medium IKF values ​​are 17.8 mm and 11.6 mm with isolate codes LSP 3 and LSP 5. The lowest IKF values ​​were 7.33 mm, 6.4 mm, 5 mm, 4.7 mm, 4.2 mm and 2.8 mm with isolate codes LSP 2, LSP 10, LSP 7, LSP 8, LSP 9, and LSP 4. Bacterial isolates with the highest IKF values ​​were inoculated on soil media for corn crop growth. LSP 1 bacteria was able to significantly affect the growth of corn plant height by 27.7 cm.
Keywords: Phosphate Solubilizing Bacteria (BPF), Mangroves, Corn Plants
Tema 210 do Supremo Tribunal Federal e sua aplicação nas ações de ressarcimento movidas por seguradoras contra transportadores internacionais
Authors: Muchiuti Thais 
Published: August 2022

No presente trabalho analisaremos o julgamento do Recurso Extraordinário nº 636.331 sob a ótica do direito internacional, o qual avaliou tema de repercussão geral acerca da aplicação das Convenções de Varsóvia e de Montreal em detrimento do Código de Defesa do Consumidor, no que diz respeito à limitação da responsabilidade das empresas de transporte aéreo internacional por extravio de bagagem. Em seguida, estudaremos os impactos do referido entendimento nas ações de ressarcimento movidas por seguradoras contra transportadores internacionais, bem como a orientação dos tribunais quanto ao tema.
Synovium secretome as a disease-modifying treatment for equine osteoarthritis
Authors: Hernandez Santiago Mejia , Begum Laila , Keller Laura E. , Fu Qin , Zhang Sheng , Fortier Lisa A. 
Published: August 2022

Abstract

OBJECTIVE
To identify chondroprotective factors as potential disease-modifying osteoarthritis treatments using an unbiased, bottom-up proteomics approach.

SAMPLES
Paired equine cartilage explants and synovial membrane were collected postmortem from 4 horses with no history of lameness and grossly normal joints at necropsy.

PROCEDURES
Six groups were established: cartilage, synoviocytes, and cartilage + synoviocytes (coculture), all with or without interleukin (IL)-1β. The catabolic effect of IL-1β was verified by glycosaminoglycan (GAG) released from cartilage into media by 1,9-dimethyl-methylene blue assay and cartilage toluidine blue histochemistry. Conditioned media from cocultures with or with IL-1β were submitted for bottom-up proteomic analysis. Synoviocyte gene expression was evaluated using reverse transcription–quantitative PCR (RT-qPCR) for proteins of interest identified in the proteomics scan.

RESULTS
GAG content was retained in cartilage when in cocultures treated with IL-1β. Fourteen proteins of interest were selected from the proteomic analysis. From these 14 proteins, metalloproteinase inhibitor 3 precursor (TIMP3), tumor necrosis factor receptor superfamily member 11B (TNFRSF11B), insulin-like growth factor-binding protein 2 (IGFBP2), and alpha-2 macroglobulin (A2M) were selected for synoviocyte gene expression analysis by RT-qPCR. Gene expression of TIMP3 (P = .02) and TNFRSF11B (P = .04) were significantly increased in synoviocytes from cocultures treated with IL-1β compared to controls. Contrary to expectations based on protein expression, IGFBP2 gene expression (P = .04) was significantly decreased in IL-1β-stimulated coculture synoviocytes compared to control coculture synoviocytes. A2M gene expression in synoviocytes was not different between coculture groups.

CLINICAL RELEVANCE
The secretome from synoviocytes could provide a milieu of bioactive factors to restore joint homeostasis in osteoarthritis.
EDUKASI KESEHATAN DAN PROMOSI KEGIATAN LEMBAGA TAHFIDZ BAITUL QUR’AN DALAM UPAYA PENCEGAHAN PENYALAHGUNAAN NARKOBA DI KELURAHAN SURAU GADANG KOTA PADANG
Authors: Syafrawati Syafrawati , Roza Shelvy Haria , Oktavina Nia , Maulani Sindi 
Published: August 2022

Nanggalo rentan dengan permasalahan sosial seperti kenakalan remaja. Survei oleh BNN tahun 2017 mendapatkan hasil bahwa golongan pelajar adalah golongan terbesar kedua yang melakukan penyalahgunaan narkoba yaitu 24% (810.267 orang pelajar). Kasus kenakalan remaja seperti penyalahgunaan narkoba, pencurian sering terjadi di sekitar Kelurahan Surau Gadang, Nanggalo. Salah satu faktor penyebab terjadinya kenakalan tersebut adalah lemahnya Pendidikan moral. Salah satu Pendidikan moral yang mumpuni adalah dengan pendekatan keagamaan. Salah satu Lembaga keagamaan adalah rumah tahfiz Al-Qur'an. Berdasarkan hasil wawancara dengan perangkat RT setempat, didapatkan bahwa belum pernah dilakukan penyuluhan tentang narkoba dikawasan tersebut. Selain itu terdapat lembaga tahfidz sebagai sarana pencegahan penyalahgunaan narkoba, namun memiliki santri yang masih minim karena kurangnya promosi. Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan remaja tentang narkoba dan meningkatkan promosi rumah tahfidz. Metode kegiatan adalah sosialisasi dan promosi kesehatan dengan pembagian flyer anti narkoba, edukasi tentang pencegahan narkoba kepada remaja dan promosi rumah tahfidz Baitul Qu’ran. Kegiatan dilaksanakan di Mesjid Raya Nanggalo dan Mesjid Al-Qadar. Hasil kegiatan ini menunjukkan bahwa terdapat peningkatan pengetahuan remaja sebelum dan setelah diberikan penyuluhan tentang narkoba. Sekitar 49 remaja di Kelurahan Surau Gadang telah terpapar informasi tentang keberadaan rumah tahfidz Baitul Qur’an. Diharapkan kedepannya promosi rumah tahfidz bisa dilakukan secara lebih luas seperti menggunakan media sosial.
O impacto da urbanização nos problemas ambientais em Área de Preservação Permanente: estudo de caso da faixa marginal da APP do Córrego Samambaia/DF
Authors: Maia Dayana dos Santos 
Published: August 2022

In view of the importance of Permanent Preservation Areas (PPA), this article aims to analyze how the advance of urbanization has negatively affected the local ecosystem of the Samambaia Stream PPA located in Distrito Federal (DF). The analysis is conducted between 1990 and 2020 in the region of the stream limited to the Administrative Region Vicente Pires/DF (RA-XXX). From bibliographical research, the supervised classification method and field research, the goal is to map the progress of urbanization and degradation of the local vegetation, as well as to portray the historical context of these processes in the RA-XXX. In addition, the research points out the environmental issues that exist in the area due to urban expansion. The results show that there was a considerable loss of vegetation cover in the range of the Samambaia Stream PPA due to urbanization. The suppression of the vegetation in the area of about 16% has caused several environmental issues both in the PPA and for the populations near the region. Keywords: Permanent Preservation Area; Samambaia Stream; Vegetation; Urbanization; Environmental problems.O impacto da urbanização nos problemas ambientais em Área de Preservação Permanente: estudo de caso da faixa marginal da APP do Córrego Samambaia/DF R E S U M OTendo em vista a importância das Áreas de Preservação Permanente (APP), este artigo tem como objetivo analisar de que forma o avanço da urbanização afetou negativamente o ecossistema da APP do Córrego Samambaia localizada no Distrito Federal (DF).. A análise é realizada entre os anos de 1990 a 2020 na região do córrego circunscrita à Região Administrativa Vicente Pires/DF (RA-XXX). A partir de pesquisa bibliográfica, do método da classificação supervisionada e de saídas de campo, o artigo mapeia o avanço da urbanização e da degradação da vegetação local, bem como resgata o contexto histórico desse processo na RA-XXX. Além disso, a pesquisa identifica os problemas ambientais presentes na área devido à expansão urbana. Os resultados mostram que houve uma perda considerável da cobertura vegetal da faixa marginal da APP do Córrego Samambaia devido à urbanização. A supressão da vegetação na área em cerca de 16% ocasionou diversos problemas ambientais tanto na APP quanto para as populações próximas à região.Palavras-chave: Área de Preservação Permanente; Córrego Samambaia Vegetação; Urbanização; Problemas Ambientais.
The influence of antimicrobial packaging on ensuring the quality and safety of food products in the conditions of war
Authors: Koziy Tatyana , Pochtarev Sergey 
Published: August 2022

The subject of the study: the need to provide antimicrobial packaging using antimicrobial substances of both organic and inorganic origin to ensure the quality and safety of food products in emergency conditions: war, pandemic, etc. The purpose of the article is to highlight the need to create hygienic safety of the population's health and ensure the safety of food products, which are of crucial importance for survival in the conditions of war and the epidemiological situation. Field of application of results. The results of the research can be used in the activities of manufacturing enterprises, enterprises in the field of commodity science, institutions of higher education to increase the effectiveness of practical training of specialists in commodity science. Results of the work. Based on the conducted research, the impact of antimicrobial packaging on ensuring the quality and safety of food products in emergency situations in the country (war, pandemics, etc.) was considered. Conclusions. Therefore, the main purpose of food packaging is to protect them from microbial and chemical contamination, from oxygen, water vapor and light. Therefore, the type of packaging plays an important role in determining the shelf life of food products, especially for storage in special conditions. Thanks to the correct choice of packaging materials and packaging technology, it is possible to guarantee the high quality and freshness of the product during the time required for its industrial production and consumption.