bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Halász–Székely barycenter
Authors: Bochi Jairo , Iommi Godofredo , Ponce Mario 
Published: October 2022

AbstractWe introduce a notion of barycenter of a probability measure related to the symmetric mean of a collection of non-negative real numbers. Our definition is inspired by the work of Halász and Székely, who in 1976 proved a law of large numbers for symmetric means. We study the analytic properties of this Halász–Székely barycenter. We establish fundamental inequalities that relate the symmetric mean of a list of non-negative real numbers with the barycenter of the measure uniformly supported on these points. As consequence, we go on to establish an ergodic theorem stating that the symmetric means of a sequence of dynamical observations converge to the Halász–Székely barycenter of the corresponding distribution.
Caesarean delivery in Uganda: Do non-clinical factors explain the trend?
Authors: Nakinobe Flavia Gladys , Lwanga Charles , Ojiambo Wandera Stephen , Kalule-Sabiti Ishmael , Mangombe Kudzaishe 
Published: October 2022

AbstractThe aim of this paper was to assess the association between non-clinical factors and Caesarean delivery in Uganda. Self-reported data from the individual recode file were extracted from the 2016 Uganda Demographic and Health Survey (UDHS), with a sub sample of 9929 women aged 15-49 with a recent birth in the last 5 years preceding the survey. Chi-square tests and multivariate comlementary log-log regression models were used to examine the relationship between non-clinical factors and Caesarean section delivery. About one in ten (7%) of the women aged 15-49 had Caesarean deliveries. Non-clinical factors which were significantly associated with Caesarean section delivery include advanced maternal age, having the first birth compared to subsequent births, having 1-3 children compared to 4 or more children, higher level of women’s education relative to no education, being in the middle, richer, and richest wealth quintile compared to the poorest quintile. In conclusion, evidence suggests that the trend in Caesarean delivery can be attributed partially to non-clinical factors including advanced maternal age, birth order, parity, women’s education level, and wealth quintile. Thus, efforts to address the trend in Caesarean section delivery, need to take account of non-clinical factors.
When Bigger is Better: The Impact of a Tiny Tick Size on Undercutting Behavior
Authors: Dyhrberg Anne H. , Foley Sean , Svec Jiri 
Published: October 2022

AbstractEconomically insignificant tick sizes encourage undercutting behavior, thus harming market quality. Theoretical work shows that increasing tick sizes in unconstrained markets reduces undercutting and improves market quality. Equity market pricing grids are generally too coarse to test this prediction. We examine a cryptocurrency market with infinitesimal tick sizes where undercutting limit orders acquire price priority without meaningful economic cost. We show that increasing tick sizes reduces undercutting behavior, increases liquidity provision and quoted depth, and reduces transaction costs for institutional and retail-sized trades while decreasing short-term volatility. Tiny tick sizes are suboptimal, supporting increased minimum trading increments in tick-unconstrained markets.
Whole God and whole man: Deification as incarnation in Maximus the Confessor
Authors: Korb Samuel 
Published: October 2022

AbstractMaximus the Confessor says that the Word of God wills to be embodied always and in all things. Against many who wish to render this ‘universal incarnation’ metaphorical, I attempt a literal reading. When Maximus speaks of the Word's universal incarnation, he refers to the deification of human beings, which constitutes a single reality with the Word's incarnation. For Maximus, deification perfectly realises and completes the very logic of the Word's incarnational descent: just as God became whole man while remaining whole God, human beings will become whole God while remaining wholly human. Herein all things become enhypostasised into the Word – rendered one by grace with Christ himself, through his humanity – and so the Word becomes embodied in all things.
Some representations of real numbers using integer sequences
Authors: Mazo Loïc , Da Col-Jacob Marie-Andrée , Fuchs Laurent , Magaud Nicolas , Skapin Gaëlle 
Published: October 2022

AbstractThe paper describes three models of the real field based on subsets of the integer sequences. The three models are compared to the Harthong–Reeb line. Two of the new models, contrary to the Harthong–Reeb line, provide accurate integer “views” on real numbers at a sequence of growing scales
$B^n$
(
$B\ge2$
).
Efficacy of cibenzoline for hypertrophic obstructive cardiomyopathy in paediatric patients with RAS/MAPK pathway syndromes
Authors: Watanabe Kota , Maruo Yuji , Takeda Atsuhito 
Published: October 2022

AbstractRASopathies – caused by mutations in the RAS/MAPK signaling pathway – are frequently associated with cardiac diseases, such as hypertrophic obstructive cardiomyopathy. Although cibenzoline is useful for adult hypertrophic obstructive cardiomyopathy patients, little is known about its effect in children. Here, we report two paediatric cases of hypertrophic obstructive cardiomyopathy associated with RASopathies where the condition was improved by cibenzoline.
Nutrition Program Fidelity Assessment tool: a framework for optimising implementation in military dining facilities
Authors: Kirkpatrick Katie M , Kleinberger Carolyn A , Moylan Elizabeth M , Bukhari Asma S , Deuster Patricia A 
Published: October 2022

AbstractObjective:The aim was to develop, refine and assess the usefulness of the Go for Green® (G4G) 2.0 Program Fidelity Assessment (PFA) tool. G4G 2.0 is a Department of Defense programme designed to optimise access, availability and knowledge of high-performance nutritious foods in military dining facilities (DFAC).Design:During a multi-site study to evaluate G4G 2.0 on meal quality and diner satisfaction, subject matter experts developed and refined a PFA tool based on eight programme requirements (PR). They identified tasks critical to programme success and corresponding benchmarks, then proposed expansion of several PR and developed a scoring system to assess adherence. Three PFA were conducted (Site 1, Site 2A and Site B).Setting:Two DFAC in the USA implementing the G4G 2.0 programme.Participants:Military DFAC participating in a G4G 2.0 evaluation study.Results:After G4G 2.0 implementation, Site 1 conducted a PFA and met benchmarks for eight of fifteen sections. At Site 2, a PFA was conducted after G4G 2.0 implementation (Site 2A) and one 3 months later (Site 2B) with twelve of fifteen and ten of fifteen sections meeting benchmarks, respectively.Conclusion:Research highlights the need to maximise implementation quality to ensure interventions are effective, achievable and efficient. Using a PFA tool to objectively assess nutrition interventions can inform programme fidelity, successes and opportunities for improvement. Results identify key areas that require additional training and resources to optimise access to nutrient-dense foods that support nutritional fitness. This feedback is critical for assessing potential programme impact on Service Members.
On the primacy of economic property rights
Authors: Allen Douglas W. 
Published: October 2022

AbstractBart Wilson suggests that economists interested in property rights have it all backwards when they define ownership as a bundle of rights. Rather he argues that ownership comes first in the form of an abstract concept. I claim there is a small element of truth to this, but the bulk of what he argues is already understood through the concept of economic property rights. Wilson's consternation is mostly the result of a failure to appreciate this latter concept.
Broadleaf weed control and white clover response to florpyrauxifen-benzyl + 2,4-D and common pasture herbicides
Authors: Greene Wykle C. , Hagood Scott , Tracy Benjamin , Abaye Ozzie , Flessner Michael L. 
Published: October 2022

AbstractThe combination of florpyrauxifen-benzyl + 2,4-D is a new, pre-packaged herbicide mixture for use in pastures and hayfields in the United States. Unlike many other pasture herbicides, florpyrauxifen-benzyl + 2,4-D is reported to preserve white clover. However, limited research exists on the efficacy of florpyrauxifen-benzyl + 2,4-D on common weed species and on the level of tolerance of white clover to it. Field trials were conducted in Virginia in 2018 to 2020 to evaluate control of various broadleaf weeds with florpyrauxifen-benzyl + 2,4-D compared to other commonly used herbicides. Field and greenhouse studies were also carried out to assess white clover tolerance. Weed species evaluated included bulbous buttercup, Canada thistle, horsenettle, and broadleaf plantain. Florpyrauxifen-benzyl + 2,4-D provided 75% to 99% control of all weeds 90 d after application except for horsenettle (56%), while causing the least white clover injury of any herbicide treatment that was evaluated. Spring herbicide applications resulted in greater bulbous buttercup control compared to fall applications, but florpyrauxifen-benzyl + 2,4-D provided greater than 81% control from both application timings. There were no differences in aboveground biomass between white clover varieties; however, all herbicides reduced white clover biomass compared to a nontreated control. This research suggests that florpyrauxifen-benzyl + 2,4-D can improve overall forage quality by controlling broadleaf weeds in mixed grass-legume stands while preserving white clover.
New directions in weed management and research using 3D imaging
Authors: Dobbs April M. , Ginn Daniel , Skovsen Søren Kelstrup , Bagavathiannan Muthukumar V. , Mirsky Steven B. , Reberg-Horton Chris S. , Leon Ramon G. 
Published: October 2022

AbstractRecent innovations in 3D imaging technology have created unprecedented potential for better understanding weed responses to management tactics. Although traditional 2D imaging methods for mapping weed populations can be limited in the field by factors such as shadows and tissue overlap, 3D imaging mitigates these challenges by using depth data to create accurate plant models. Three-dimensional imaging can be used to generate spatiotemporal maps of weed populations in the field and target weeds for site-specific weed management, including automated precision weed control. This technology will also help growers monitor cover crop performance for weed suppression and detect late-season weed escapes for timely control, thereby reducing seedbank persistence and slowing the evolution of herbicide resistance. In addition to its many applications in weed management, 3D imaging offers weed researchers new tools for understanding spatial and temporal heterogeneity in weed responses to integrated weed management tactics, including weed–crop competition and weed community dynamics. This technology will provide simple and low-cost tools for growers and researchers alike to better understand weed responses in diverse agronomic contexts, which will aid in reducing herbicide use, mitigating herbicide-resistance evolution, and improving environmental health.
The Contribution of Transpiration to Precipitation Over African Watersheds
Authors: Te Wierik S. A. , Keune J. , Miralles D. G. , Gupta J. , Artzy‐Randrup Y. A. , Gimeno L. , Nieto R. , Cammeraat L. H. 
Published: October 2022

AbstractThe redistribution of biological (transpiration) and non‐biological (interception loss, soil evaporation) fluxes of terrestrial evaporation via atmospheric circulation and precipitation is an important Earth system process. In vegetated ecosystems, transpiration dominates terrestrial evaporation and is thought to be crucial for regional moisture recycling and ecosystem functioning. However, the spatial and temporal variability in the dependency of precipitation on transpiration remains understudied, particularly in sparsely sampled regions like Africa. Here, we investigate how biological and non‐biological sources of evaporation in Africa contribute to rainfall over the major watersheds in the continent. Our study is based on simulated atmospheric moisture trajectories derived from the Lagrangian model FLEXPART, driven by 1° resolution reanalysis data over 1981–2016. Using daily satellite‐based fractions of transpiration over terrestrial evaporation, we isolate the contribution of vegetation to monthly rainfall. Furthermore, we highlight two watersheds (Congo and Senegal) for which we explore intra‐ and interannual variability of different precipitation sources, and where we find contrasting patterns of vegetation‐sourced precipitation within and between years. Overall, our results show that almost 50% of the annual rainfall in Africa originates from transpiration, although the variability between watersheds is large (5%–68%). We conclude that, considering the current and projected patterns of land use change in Africa, a better understanding of the implications for continental‐scale water availability is needed.
Characterization of Multi‐Scale Fluvial Suspended Sediment Transport Dynamics Across the United States Using Turbidity and Dynamic Regression
Authors: Wang Kezhen , Steinschneider Scott 
Published: October 2022

AbstractThis study explores multi‐scale variability in the relationship between turbidity (Tn) and flow (Q) in 162 watersheds across the contiguous United States. Sites are selected where Tn acts as a good surrogate for suspended sediment concentration. We use dynamic linear models (DLMs) to infer time‐varying parameters of Tn‐Q rating curves at each site, and calibrate a hyper‐parameter of the DLM model () to quantify the degree of dynamicity in the rating curve relationship. The DLM can capture dynamics in the Tn‐Q relationship at the resolution of the data (daily in this study), enabling an analysis of the dynamics across time scales. Regional multivariate regressions are used to identify physiographic features that relate to the magnitude of and spectral signatures in the DLM parameters across sites. Results show that watersheds in the Midwest and Pacific Northwest tend to exhibit more variable Tn‐Q relationships, while these relationships are more stable in watersheds in the humid east and Lower Mississippi River basin. Stream network complexity, soil composition, perennial snow coverage, saturation‐excess overland flow, and modifications to the stream network are associated with the dynamicity in the Tn‐Q relationship. DLM parameters exhibit cyclic behavior at sub‐monthly, sub‐annual, and annual time scales at sites across the country, with annual cycling associated with basin features that reflect watershed sediment availability and the erosive power of rivers. Overall, our analysis highlights significant multi‐scale variability in Tn‐Q relationships across the nation, with important implications for how sediment dynamics should be measured and managed at the watershed‐scale.
Penetrative Strain and Partitioning of Convergence‐Related Shallow Crustal Shortening, Across Scales, in the Lesser‐ and Sub‐Himalayan Thrusts: Insights From the Eastern Himalaya, Sikkim
Authors: Parui Chirantan , Bhattacharyya Kathakali , Ghosh Pritam 
Published: October 2022

AbstractShortening estimates from regional balanced cross‐sections remain lower than the predicted shortening from paleomagnetism and area‐balancing methods in the Himalaya. To reconcile this shortening deficit, we evaluate the shortening contribution from the often‐ignored penetrative strain of quartz grains and integrate these results with two published regional balanced cross‐sections from Sikkim Himalaya. Penetrative strain progressively decreases from the internal to the external thrusts with changing deformation conditions. Strain increases toward the basal thrust zone within each thrust indicating strain localization. Strain ellipsoids are folded along with the thrusts indicating the strain initiated before thrusting and folding. The layer‐normal shortening (LNS) strain dominates the internal thrusts. A combination of LNS and layer‐parallel shortening (LPS) strain exist in the low‐strained external thrust sheets. Approximately 78–91 km of shortening is recorded as penetrative strain in the Lesser‐ and Sub‐Himalayan thrusts. Lateral structural variations in the thrusts are reflected in the thrust‐sheet scale shortening and in the strain ellipsoid orientations, but not in the grain‐scale shortening. Shortening is partitioned differently across scales; the duplex records the highest thrust‐sheet scale shortening, while the roof thrust toward the hinterland records the highest grain‐scale shortening. Due to the dominance of LNS strain, removing strain from thrusts will collectively decrease ∼54–59 km of base lengths, thereby reducing the total minimum shortening of the Sikkim Himalaya by ∼13%. Therefore, the penetrative strain does not contribute to the shortening deficit in the Sikkim Himalaya.
JAK/BCL2 inhibition acts synergistically with LSD1 inhibitors to selectively target ETP-ALL
Authors: Benyoucef Aissa , Haigh Katharina , Cuddihy Andrew , Haigh Jody J. 
Published: October 2022

AbstractETP-ALL (Early T cell Progenitor Acute Lymphoblastic Leukemia) represents a high-risk subtype of T cell acute lymphocytic leukemia (T-ALL). Therapeutically, ETP-ALL patients frequently relapse after conventional chemotherapy highlighting the need for alternative therapeutic approaches. Using our ZEB2Tg ETP-ALL mouse model we previously documented the potential utility of the catalytic LSD1 inhibitor (GSK2879552) for treating mouse/human ETP-ALL. However, this approach proved to be inefficient, especially in killing human LOUCY cell ETP-ALL xenografts in vivo. Here we have revealed the novel involvement of ZEB2/LSD1 complexes in repressing the intrinsic apoptosis pathway by inhibiting the expression of several pro-apoptotic proteins such as BIM (BCL2L11) as a major driver for ETP-ALL survival. Treatment with LSD1i (particularly with the steric inhibitor SP2509) restored the expression of ZEB2/LSD1 pro-apoptotic BIM (BCL2L11) target. In combination with a JAK/STAT pathway inhibitor (JAKi, Ruxolitinib) or with a direct inhibitor of the anti-apoptotic BCL2 protein (BCL2i, ABT-199) resistance of human and mouse ETP-ALL to LSD1i was reversed. This new combination approach efficiently inhibited the growth of human and mouse ETP-ALL cells in vivo by enhancing their differentiation and triggering an apoptotic response. These results set the stage for novel combination therapies to be used in clinical trials to treat ETP-ALL patients.
The association of serum vitamin D with incident diabetes in an African American population
Authors: Joseph Joshua J. , Langan Susan , Lunyera Joseph , Kluwe Bjorn , Williams Amaris , Chen Haiying , Sachs Michael C. , Hairston Kristin G. , Bertoni Alain G. , Hsueh Willa A. , Golden Sherita H. 
Published: October 2022

AbstractBackgroundIncident diabetes risk is inversely proportional to 25-hydroxyvitamin D [25(OH)D] levels among non-Hispanic white but is unclear among African American (AA) populations. Serum 25(OH)D2 may be an important component of total 25(OH)D among AA populations due to higher levels of melanin.ObjectiveTo assess the association of serum 25(OH)D with incident diabetes among AAs and stratify by detectable 25(OH)D2.DesignSerum 25(OH)D2 and 25(OH)D3 were collected from 2000 to 2004 among AA participants in the Jackson Heart Study. A cosinor model was used to adjust for the seasonality of 25(OH)D3; 25(OH)D3 and 25(OH)D2 were combined to ascertain total 25(OH)D. Incident diabetes (fasting glucose ≥126 mg/dl, use of diabetes drugs, or HbA1c ≥6.5%) was assessed over 12 years among adults without diabetes at baseline. Participants with missing baseline covariates or diabetes follow-up were excluded. Hazard ratios (HR) were estimated using Cox modeling, adjusting for age, sex, education, occupation, smoking, physical activity, alcohol use, aldosterone, and body-mass index.ResultsAmong 3311 adults (mean age 53.3 years, 63% female) 584 participants developed diabetes over a median of 7.7 years. After adjustment, 25(OH)D ≥20 compared to <12 ng/ml was associated with a HR 0.78 (95% CI: 0.61, 1.00). Among participants with detectable 25(OH)D2 and 25(OH)D3 (n = 1671), 25(OH)D ≥ 20 ng/ml compared to <12 ng/ml was associated with a 35% (HR 0.65, 95% CI: 0.46, 0.91) lower risk of diabetes.ConclusionsHigher levels of 25(OH)D may be protective against the development of diabetes among AA individuals, particularly among those with detectable 25(OH)D2 and 25(OH)D3.
A Posteriori dietary patterns, insulin resistance, and diabetes risk by Hispanic/Latino heritage in the HCHS/SOL cohort
Authors: Maldonado Luis E. , Sotres-Alvarez Daniela , Mattei Josiemer , Daviglus Martha L. , Talavera Gregory A. , Perreira Krista M. , Van Horn Linda , Mossavar-Rahmani Yasmin , LeCroy Madison N. , Gallo Linda C. , Albrecht Sandra S. 
Published: October 2022

Abstract
Objective
We examined links among dietary patterns (DPs), insulin resistance (IR), and diabetes risk by heritage in the Hispanic Community Health Study/Study of Latinos.

Methods
Hispanics/Latinos of Cuban, Dominican, Mexican, Puerto Rican, Central American, and South American heritage aged 18–74 years and diabetes-free completed two 24 h dietary recalls at baseline (2008–2011) and provided 6-year follow-up data (2014–2017; n = 7774). We classified 6-year IR status [improved, unchanged (referent), worsened] using a 1-SD change in fasting insulin between visits and defined incident diabetes based on American Diabetes Association criteria. We derived heritage-specific DPs via principal factor analysis and estimated their associations with 6-year IR status (multinomial) and incident diabetes (binary) using complex survey-based logistic regression.

Results
Five overarching DPs based on high-loading foods were shared by two or more heritage groups: “Burger, Fries, & Soft Drinks”; “White Rice, Beans, & Red Meats”; “Fish & Whole Grains”; “Cheese & Sweets”; and “Stew & Corn”. Comparing highest-to-lowest DP quintiles, the Dominican “Burger, Fries, & Soft Drinks” and Cuban “White Rice, Beans, & Red Meats” DPs were associated with worsened 6-year IR status (log-odds: 2.35, 95% CI: 1.02, 3.68, Ptrend = 0.037 and log-odds: 1.27, 95% CI: 0.49, 2.06, Ptrend = 0.009, respectively). The Puerto Rican “Burger, Fries, & Soft Drinks” and the Central American “White Rice, Beans, & Red Meats” DPs were associated with greater diabetes incidence (OR: 3.00, 95% CI:1.50, 5.99 and OR: 2.41, 95% CI: 1.05, 5.50, respectively).

Conclusions
A diet characterized by higher intakes of burgers, fries, and soft drinks and another characterized by higher intakes of white rice, beans, and red meats may be adversely associated with IR and diabetes risk in some Hispanic/Latino heritage groups. Future work is needed to offer more heritage-specific dietary guidance for diabetes prevention in this population.