bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative premedication efficacy of gabapentin, melatonin, and dextromethorphan in postoperative pain management following general anesthesia in hip fracture surgery
Authors: Modir Hesameddin , Mahmoodiyeh Behnam , Azami Mehran , Behnamimoghadam Armita , Almasi-Hashiani Amir 
Published: May 2022

Background
The effectiveness of postoperative pain relief regimens is well established and postulated to rely on diverse factors.

Objective
The aim of this study was to compare the effect of gabapentin and melatonin and dextromethorphan on postoperative pain control in patients undergoing hip fracture surgery under general anesthesia.

Patients and methods
In a double-blind controlled trial 125 patients requiring hip fracture surgery enrollment into the study after following ethical approval and informed participant consent. The patients were randomized to either each of the three regimens (gabapentin, melatonin, and dextromethorphan) by the block-randomization method. Outcome measurements were of foremost importance, patient’s pain scores throughout the recovery time and scheduled postoperative time intervals (2, 4, 6, 12, 24 h), doses of opioid use (mg) in the initial 24 h, and at length, sedation levels using the Ramsay scoring system at the early postoperative time intervals. Moreover, complications including chills, nausea, vomiting, and decreased consciousness were recorded. Statistical data analysis conducted by analysis of variance, χ
2, and repeated measurements through SPSS, version 20.

Results
Gabapentin-treated patients manifested the lowest blood pressures (P<0.05), with maximum pain relief being experienced, sedation level being greater (P<0.05), and opioid use being lower in the group (P=0.0001).

Conclusion
We have the impression that gabapentin could be connected with improving pain relief and sedation, whereas opioid use was observed comparatively lower in the initial 24 h, and hence inferentially. The premedication can be driven to be superior in creating favorable conditions for analgesia and sedation and effective in preventing complications requiring treatment within 24 h postoperatively versus baseline and promisingly suggested to be continued for postoperative pain management, procedural sedation quality improvement, and opioid use reduction within the initial 24 h.
Comparative studies of free and immobilized partially purified lipase from Aspergillus niger NRRL-599 produced from solid-state fermentation using gelatin-coated titanium nanoparticles and its application in textile industry
Authors: El Menoufy Hassaan A. , Gomaa Sanaa K. , Haroun Ahmed A. , Farag Ali N. , Shafei Mona S. , Shetaia Yousseria M. , Abd El Aal Rania A. 
Published: May 2022

Background and objective
Lipases (triacylglycerol acylhydrolase, EC. 3.1.1.3) belong to a class of hydrolases that are specific for the hydrolysis of fats into fatty acids and glycerol that have much application in different industrial processes. Fungi, yeast, and bacteria have been reported to be sources of lipase. There are many immobilized methods for enzyme, and the commonly used methods are physical adsorption, entrapment, and cross-linkage. This study aimed to evaluate lipase production by Aspergillus niger NRRL-599 in solid cultivation using agro-industrial waste as a substrate. Partial purification of the crude enzyme and its characterization and immobilization using nanoparticles were carried out. The potential application of the immobilized and partially purified enzyme was also studied in the field of textile.

Materials and methods
Partially purified A. niger NRRL-599 lipase was immobilized by physical adsorption onto modified titanium dioxide nanoparticles using gelatin and palmitic acid binders and characterized by transmission electron microscopy, dynamic light scattering, and Fourier-transform infrared.

Results and conclusion
In our study, lipase produced by A. niger NRRL-599 was partially purified by ammonium sulfate at 60% saturation and immobilized on gelatin-coated titanium dioxide. Comparison between the properties of the free and the immobilized A. niger NRRL-599 lipase forms was carried out. The optimum pH was 9.0 and 10.0 for the free and immobilized forms, respectively. The half-life of the soluble-free lipase at 50 and 55°C was 17.3 and 23.1 min, respectively, whereas for the immobilized form was 23.1 and 34.6 min, respectively. At 50 and 55°C, the deactivation rate constants (kD) for soluble lipase were 6.6×10−3 and 5×10−3, respectively, and 6.6×10−3 and 3.3×10−3, respectively, for immobilized lipase. The K
m was 11.11 and 12.5 mM for the immobilized and free forms, respectively. The V
max was 416.6 U/mg protein and 296.3 U/mg protein for immobilized and free lipase forms, respectively. This confirms that the apparent affinity toward the substrate increases by immobilization. Partially purified lipase and immobilized enzymes were used in the textiles in the treatment of wool fibers before dying to improve the color strength.
Chemotherapy or chemotherapy followed by consolidation chemoradiation in postoperative (simple cholecystectomy) gall bladder cancer with residual disease, unsuitable for revision surgery? Risk stratification and outcomes
Authors: Alam Md. Nawed , Agrawal S. , Rastogi N. , Saxena Rajan 
Published: May 2022

ABSTRACT

Background:
Revision surgery (RS) is the standard of care for gallbladder cancer (GBC) after simple cholecystectomy (SC). Often these patients are unsuitable for RS due to late referral or unresectable disease. Do such patients benefit with chemotherapy (CT) alone or dual-modality (CT followed by consolidation chemoradiotherapy [CTRT])? In the absence of any guidelines, we reviewed our data with CT or CTRT to inform us regarding adequate therapy.

Materials and Methods:
Patients of GBC post-SC referred to us (January 2008 to December 2016) were risk-stratified into three categories based on a diagnostic CT scan: No residual disease (NRD), limited volume residual disease (LR1: Residual/recurrent disease in GB bed with or without N1 nodal station involvement), advanced residual disease (LR2: Residual/recurrent disease involving GB bed with N2 nodal station involvement) and treated with CT or CT followed by CTRT. Response to therapy (RECIST), overall survival (OS), and adverse prognostic factors affecting OS were evaluated.

Results:
Out of 176 patients, 87were nonmetastatic (NRD = 17, LR1 = 33 and LR 2 = 37). 31 received CT, 49 CTRT and 8 defaulted. At a median follow up of 21 months, the median OS with CT versus consolidation CTRT was not reached in NRD (P = 0.57), 19 months versus 27 months in LR1 (P = 0.003) and 14 months versus 18 months in LR 2 (P = 0.29), respectively. On univariate analysis, residual disease burden, type of treatment (CT vs. CTRT), N stage, and response to treatment were found statistically significant.

Conclusion:
Our data suggest that CT followed by CTRT improves outcomes in patients with limited volume disease.
Computed tomography-based radiomics nomogram model for predicting adherent perinephric fat
Authors: Ma Teng , Cong Lin , Xu Jingxu , Huang Chencui , Ma Qianli , Hua Qianqian , Li Xiaojiao , Huang Zhaoqin , Wang Ximing , Chen Yunchao 
Published: May 2022

Aims:
We investigated the predictive value of a computed tomography (CT)-based radiomics nomogram model for adherent perinephric fat (APF).

Materials and Methods:
The data of 220 renal carcinoma patients were collected retrospectively. Patients were divided into training (n= 153) and validation cohorts (n= 67). Radiomics features were extracted from plain CT scans, while radscore was generated by a linear combination of selected radiomics features and their weighting coefficients. Univariate logistic regression was used to screen clinical risk factors. Multivariate logistic regression combined with radscore was used to screen final predictors to construct a radiomics nomogram model. Receiver Operating Characteristic curves were used to evaluate the predictive performance of models.

Results:
Thirteen radiomics features associated with APF achieved a good predictive effect. The overall area under the curve (AUC) of the radscore model was 0.966, and that of the training and validation cohorts was 0.969 and 0.956, respectively. Gender, age, hypertension, size, perinephric fat thickness, Mayo Adhesive Probability score, neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio, systemic inflammation response index, and systemic immune-inflammation index were risk factors for APF (P < 0.05). The overall AUC of the radiomics nomogram model based on radiomics features and clinical factors, the training, and validation cohorts was 0.981, 0.997, and 0.949, respectively. Both models had high diagnostic efficiency. However, their differential diagnostic accuracy was higher than that of the clinical model. Additionally, the radiomics nomogram model had higher AUC and specificity.

Conclusions:
The radiomics nomogram model is a prediction tool based on radiomics features and clinical risk factors and has high prediction ability and clinical application value for APF.
KARAKTERISTIK OPERATOR PARANORMAL- * QUASI
Authors: Gunawan Gunawan , Widiyastuti Erni 
Published: May 2022

Given Hilbert space H over the fields of . This study aimed to investigate the paranormal- * quasi operators and their properties in Hilbert space. The study resulted the properties of paranormal- * quasi operators, hyponormal operator, class A operator, Class A- * operator, p- hyponormal operator for p > 0, - paranormal operators, compact operator, and the relationship between them
Título en español
Authors: D. G. St. Louis  , J. Vélez-Santiago  , J. A. Arroyo-Aguilú  , R. E. McDowell  
Published: May 2022

Un estudio para determinar el efecto de un pienso suplementario de alta calidad sobre la tasa de crecimiento de novillas lecheras se realizó en la Subestación de Corozal. Dieciséis novillas con un peso medio de 190 kg se sometieron previamente a un apacentamiento de pasto Angola (Digitaria decumbens), abonado intensamente, por un período de 43 días, al cabo del cual se asignaron en grupos iguales a pacer el pasto Pangola solo (T1) o a pacerlo suplementado con 2.27 kg diarios de bolas hechas de la planta íntegra de maíz (T2). El apacentamiento se realizó a razón de cinco novillas por ha, alternándose cada tratamiento entre cuatro cercados de .40 ha cada uno. La rotación de los animales en ambos tratamientos se realizó simultáneamente. Estos se pesaron a intervalos de 5 a 7 días. El estudio se completó cuando los animales alcanzaron 320 kg de peso medio. Durante las primeras semanas, la suplementación con las bolas de maíz demostró ser detrimental a la ganancia de peso, ya que la ganancia en las novillas en T1 fue mayor que la de las en T2 a causa de la madurez excesiva del pasto en T2. Más adelante, las bolas fueron ventajosas, al agostarse los pastos durante la época de sequía. La ganancia media por día a los 302 días fue de .29 y .44 kg para las novillas en T1 y T2, respectivamente. Se tomaron muestras de los pastos antes y después del apacentamiento cortándose 6 cuadros de 0.84 m2 cada uno en cada ocasión. Las diferencias entre los redimientos del pasto antes y después del apacentamiento fueron significativas. Los tratamientos, el muestreo antes y después del apacentamiento, los ciclos y los pastos arrojaron diferencias significativas. La única interacción significativa fue la de ciclo con muestreo antes y después del apacentamiento, indicando el efecto de las sequías en el consumo del forraje. El estudio demostró que los forrajes de alta calidad en bolas fueron provechosos, cuando se suplieron a las novillas apacentadas en pastos que no eran suculentos ni abundantes. Se deben utilizar las bolas de maíz cuando el crecimiento de los pastos es pobre y de calidad inferior para así reducir el apacentamiento excesivo.
STUDENTS' MOTIVATION IN ENHANCING ENGLISH COMMUNICATION PROFICIENCY IN DONG NAI TECHNOLOGY UNIVERSITY, VIETNAM
Authors: Duc Nguyen Van , Hanh Le Thi 
Published: May 2022

<p>The study was conducted with the aim of finding out some main determinants related to the students’ speaking performance, not to eliminate them fast because that is impossible, at the present time, how to learn and encourage them gradually to solve the problems. The researcher believes that, when the students are clearly aware of the problems that they are encountering, they will be more positive in coping with them and improve them unconsciously. The descriptive method of research was utilized in this study to gather the necessary data and information. The independent variables are students’ motivation including their: achievement, competence motivation, power motivation, attitude motivation and incentive motivation. And the dependent variables of the students’ speaking proficiency include their: grammatical competence, strategic competence, discourse competence and sociolinguistic competence. The dependent variable focuses on English proficiency: accuracy and fluency. The respondents of the study were 30 English major students from Faculty of Foreign Languages and 6 teachers who were teaching English there, Dong Nai Technology University (DNTU).</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0939/a.php" alt="Hit counter" /></p>
INVESTIGATIONS OF PRESCHOOL TEACHERS’ VIEWS ON LEARNING CENTRES IN PRESCHOOL EDUCATION
Authors: Bolat Emine Yılmaz , Koyuncu Merve 
Published: May 2022

This study aimed to examine the views and practices of preschool teachers about learning centres. Following this purpose, 36 preschool teachers who work in Mersin are examined. The research was carried out with phenomenology which is one of the qualitative research methods. In the research, the data were collected by semi-structured interview technique. The researchers utilised "Personal Data Form" and "Learning Centres Interview Form" prepared by receiving experts' opinions to collect data in the research. The findings obtained from individual interviews with teachers were analysed with the descriptive analysis technique. In the direction of the views of the teachers, it was concluded that the teachers have different learning centres in their classrooms, majority of the teachers find the learning centres sufficient, the range of the materials in some learning centres is insufficient. Besides, the learning centres preferred by the children was the most dramatic play centre. It was concluded that preschool teachers need support for the organisation and use of the learning centres. It was suggested that the teachers plan how the families can participate by encouraging them and getting support from the families and the institution while providing the materials. Therefore, the teachers support the children's development through different learning centres instead of a single learning centre. The teachers participate in in-service training to interact with children in learning centres.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0937/a.php" alt="Hit counter" /></p>
STUDENTS' COMPETENCE OF TEACHING MULTI-MODEL TEXT AT UNIVERSITY OF EDUCATION, THAI NGUYEN UNIVERSITY, VIETNAM
Authors: Ngoc Tran Thi 
Published: May 2022

Currently, competence-based training is a fundamental trend of innovation in educational programs and methods around the world. In Vietnam, new curricula and textbooks have begun to be implemented. Therefore, teacher training institutions throughout the country need to innovate their teacher training programs towards competence development. The article presents the research results on the competence and competence to teach multimodal texts; Teaching multi-modal texts according to competence development requirements. Research results on the current situation of multimodal text-teaching competence of students majoring in Philology, University of Education - Thai Nguyen University, Vietnam are analyzed through specific survey data.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0932/a.php" alt="Hit counter" /></p>
EXTENSIVE READING: A STRATEGY TO IMPROVE VOCABULARY, READING SKILLS AND MOTIVATION IN AN EFL B2 COURSE AT THE NATIONAL UNIVERSITY OF EDUCATION (UNAE) IN ECUADOR
Authors: Sevy-Biloon Julia 
Published: May 2022

<p>Virtual and online classes have added a new level of difficulties to teaching and learning EFL. Teachers must constantly work to find innovative and new practices to engage students and help them improve their English language skills. The professor of an upper-intermediate university level cohort in Ecuador has chosen to do action research in her classroom to improve students reading skills, vocabulary building and motivation to achieve the set competencies of the B2 level. Based on previous experiences the teacher chose to implement extensive reading throughout the semester to improve the mentioned areas. The teacher first observed the areas the students needed help in, implemented a new strategy and activities, reflected on those activities, and implemented a final exam to see if students improved in reading and vocabulary. Through qualitative data analysis, the teacher was able to see students were more motivated, they improved in reading and vocabulary, and they were beginning to learn autonomously. The implementation of extensive reading was a success for most of the students to improve their English skills and can be a strategy that can be utilized in the future.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0939/a.php" alt="Hit counter" /></p>
PROBLEMS AND SOLUTIONS OF USING GROUP DISCUSSION ACTIVITIES IN GENERAL ENGLISH CLASSES AT DONG NAI TECHNOLOGY UNIVERSITY, VIETNAM
Authors: Tuyen Le Thi Hong 
Published: May 2022

The paper discusses the current state and solutions of using group discussions in general English classes at Dong Nai University of Technology. It shows that using group discussions in English speaking classes is a very active and effective teaching and learning method. However, some teachers still do not understand how to deploy group work for their students to bring the best effect. Besides, many students still face some difficulties when participating in group discussions, there are still shy students who do not dare to express their personal opinions in front of the group; rely on other group members or use Vietnamese too much in the discussion process. At the same time, the paper also points out practical solutions, appropriate to improve the problems that both teachers and students are facing during group discussions. From there, teachers can deploy and organize group discussion activities more effectively; students can be more confident during group discussions.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0925/a.php" alt="Hit counter" /></p>
ALBANIAN LITERATURE FROM THE BEGINNING OF THE XX CENTURY UNTIL 1944 ACCORDING TO THE HISTORICAL OBSERVATION OF ROBERT ELSIE
Authors: Dobroshi Veron 
Published: May 2022

<p>Robert Elsie is one of the important scholars of the Albanian language, literature, folklore and culture in general. His studies prove the great desire to know closely the Albanian land in its multidimensional aspects. He offers a positive image of Albanian values everywhere in the world. He enabled the world to know more closely the Albanian culture by becoming a model of a foreign researcher who studies the whole aspects of the culture of another country. Elsie also writes a history of Albanian literature starting from its first beginnings until the last decades of the twentieth century. Our study will focus on a certain period of Albanian literature according to the empirical experience of Robert Elsie in the Albanian space. The study aims to specify the main authors of the period from the beginning of the twentieth century to 1944, a year before the communist system was installed in Albania. This period, which spans about three or four decades, is distinguished for the thematic characteristics, forms and prominent names of authors who shed light on Albanian letters until the years before the beginning of an ideological system. The study aims to examine this stage through the research eye of Robert Elsie. How Elsie classifies the authors of Albanian literature in periods, how their literary work is related to the socio-political circumstances in the country and who are the major figures of these decades in Albanian literature are some of the issues that will be analyzed in this study.</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0907/a.php" alt="Hit counter" /></p>
EFFECT OF ASSERTIVENESS TRAINING TECHNIQUE ON BULLYING BEHAVIOUR OF SECONDARY SCHOOL STUDENTS IN ANAMBRA STATE, NIGERIA
Authors: Ekwelundu Chinyere Anthonia 
Published: May 2022

This study examined the effect of the Assertiveness Training technique on bullying behaviour of secondary school students in Anambra State. Two research questions guided the study, while two null hypotheses were tested at .05 level of significance. The study adopted a quasi-experimental, non-equivalent pre-test and post-test, control group design. A sample of 94 student bullies made up 54 males and 40 females were purposively drawn from two schools with the highest number of bullies and used for the study. Students Bullying Behaviour Identification Scale (SBBIS) and Students Bullying Behaviour Questionnaire (SBBQ) were adapted as instruments for data collection. The reliability of the instruments was established using Cronbach Alpha and with coefficients of 0.88 for SBBQ and 0.96 for SBBIS. SBBIS was administered two weeks before the commencement of the treatment aimed at identifying and screening of bullies while SBBQ was used for the pretesting and post-testing for the three groups. Mean was used to answer research questions, while the null hypotheses were tested using Analysis of Co-Variance (ANCOVA). The findings of the study revealed that the Assertiveness Training technique was effective in reducing bullying behaviours of secondary school students. The findings equally indicated that the difference in the effectiveness of the Assertiveness Training technique on bullying behaviours of male and female secondary school students was not significant. Based on the findings of the study it was recommended among others that assertiveness training techniques should be used by guidance counsellors working in secondary schools should modify behaviours of students with bullying behaviour.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/edu_01/0907/a.php" alt="Hit counter" /></p>