bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motives for COVID-19 vaccine hesitancy amongst marginalized groups, including homeless persons and migrants, in France: a mixed-methods study.
Authors: Ducarroz Simon , Figueiredo Natasha , Scarlett Honor , Aarbaoui Tarik El , Vignier Nicolas , Longchamps Cécile , Allaire Cécile , Perrin Adèle , Poveda Juan Diego , Davisse-Paturet Camille , Melchior Maria 
Published: June 2022

Abstract
Background: Persons experiencing unstable housing – including recently arrived migrants – are at elevated risk of contracting COVID-19 and suffer from high morbidity and mortality. In this context, the COVID-19 vaccine was foreseen as a promising way to control the pandemic and reduce social inequalities in this area. Understanding the motives of COVID-19 vaccine acceptability in people with unstable housing, including migrants, is therefore crucial to tailor public health communication and outreach. Thus, the main objective of our study was to investigate - both quantitatively and qualitatively – the motivations behind vaccine hesitancy in people experiencing unstable housing when vaccines became available in France.Methods: A cross-sectional study was performed in Spring 2021, using convergent mixed-methods approach. Participants were recruited from homeless shelters and day centres and face-to-face interviews were offered, with help, where necessary, from phone-based interpreters. Factors associated with motives for COVID-19 vaccine hesitancy were explored using logistic regression models. Qualitative data – collected through semi-structured individual interviews - were analysed via an inductive thematic approach. Both quantitative and qualitative data were then integrated. Results: Vaccine hesitancy was found to be at an elevated rate (58.0%). The three most reported motives of hesitancy were related to COVID-19 vaccine effectiveness, safety, and trust in information about the vaccine. Factors of elevated hesitancy comprised the interviewees’ age, level of education, French-language aptitude, feeling of worry about COVID-19, and time of residence in France. Generic distrust in official information was a shared associated factor for the 3 motives of hesitancy. This result was expanded upon by the interview data where participants described having differential trust depending on who is recommending the vaccination. Another emerging key theme related to hopes that the vaccine would release them from the burden of the pandemic. Conclusions: Our mixed methods study provides a comprehensive understanding of COVID-19 vaccine hesitancy among persons with unstable housing in France in Spring 2021. Elevated levels of hesitancy remain a public health concern as “No one is safe until everyone is safe”. The already established role of trust in vaccine hesitancy is still to be adequately addressed as a potentially effective route of intervention.
An Efficient Learning Method for Image Recognition of Dental Instruments
Authors: OKA Shintaro , NOZAKI Kazunori , HAYASHI Mikako 
Published: June 2022

Abstract
Purpose
To prevent needlestick injury and leftover instruments, and to perform efficient dental treatment, it is important to know which and how many instruments are present during dental treatment. Therefore, we will obtain a dataset for image recognition of dental treatment instruments, develop a system for detecting dental treatment instruments during treatment by image recognition, and evaluate the performance of the system to establish a method for detecting instruments during treatment.
Methods
We created an image recognition dataset using 23 types of instruments commonly used in the Department of Restorative Dentistry and Endodontology at Osaka University Dental Hospital and a surgeon’s hands as detection targets. Two types of datasets were created: one annotated with only the characteristic parts of the instruments, and the other annotated with the entire parts of instruments. YOLOv4 was used as the image recognition system. The performance of the system was evaluated in terms of two metrics: detection accuracy (DA), which indicates the probability of correctly detecting the number of target instruments in an image, and the average precision (AP).
Results
The mean DA and AP for the instruments used in this study were 89.3% and 70.9%, respectively, when the characteristic parts of the instruments were annotated and 85.3% and 59.9%, respectively, when the entire parts of the instruments were annotated.
Conclusion
The detection of dental instruments can be performed efficiently by targeting the parts characterizing them.
Genetic susceptibility to bladder cancer in a cohort of 51 Lebanese patients
Authors: Kourie Hampig Raphael , Haddad Léa El , Chouery Eliane , Mehawej Cybel , Jalkh Nadine , Kassis Marwan , Zouein Joseph , Eid Roland , Haddad Fady Ghassan , Daou Bechara , Tayeh Georges Abi , Kattan Joseph , Nemr Elie 
Published: June 2022

Abstract
IntroductionBladder cancer (BC) is a highly prevalent malignancy worldwide and particularly in Lebanon. Several studies have reported genetic risk factors in GSTM1 and NAT2, as well as many modifiable and non-modifiable risk factors, associated with BC.MethodsThis is a retrospective study that includes 51 Lebanese patients with BC. Peripheral blood samples were collected from patients and DNA extraction was performed using the standard salting-out method. Whole exome sequencing (WES) was performed and was followed by a thorough analysis of GSTM1, NAT2 and a panel of 127 genes known to be implicated in different hereditary cancers, for the detection of pathogenic germline mutations in the studied individuals.ResultsOur cohort included 42 men (82.4%) and 9 women (17.6%), with a mean age at diagnosis equal to 67 years. Of all participants, 10.8% had a family member diagnosed with BC and 17.3% with other cancer types. Our WES analysis allowed the detection of a high-risk variant found in APC (rs1801155) and a variant in BRIP1 (rs28903098) that are frequent in our cohort and more prevalent in our Lebanese in-house database compared to other international databases. Furthermore, two actionable variants, one in PALB2 (rs864622498) and another in ERCC2 (rs121913016) were detected in 2 different individuals from our cohort, paving the way to personalized therapies in these patients. A variant in NAT2 (rs1799931), shown to be associated with BC in other populations, was detected in 4 patients from our cohort.ConclusionThis is the first study in Lebanon and one of very few international studies carried out by NGS in patients with BC. Further studies in larger cohorts are required to confirm our findings in the Lebanese population.
Double-Layered T-Shape Loaded Hairpin Resonator for High Performance Characteristic Dual Band BPF Design
Authors: Mohammed zainab A. , Hammed Raaed T. 
Published: June 2022

Abstract
A simple high performance compact dual band bandpass filter is developed in this paper based on multilayered T-shape loaded hairpin resonator (T-SLHR). The filter circuit is constructed using two substrates. On the first ground plane substrate, two T-SLHRs are analyzed and electrically coupled through a space gap to accomplish the desired dual passbands. To acquire the filtering response, an input/output grounded hairpin-stub is patterned on a second ungrounded-substrate and broadside coupled to the T-SLHRs. To validate the proposed concept, a dual-band BPF is realized for a multi-wireless network system working at 2.4 GHz and 3.5 GHz center frequencies. Indeed, the T-SLHR is analyzed based on odd-even theory to generate the specified frequencies. Furthermore, a block-diagram to explain the coupling mechanism of the expected filtering attitude is suggested. Moreover, the simulated filter is manufactured and its results from measurement and simulation are compared and discussed. The produced filter has quite small area less than 126 mm 2 , high skirt roll-off selectivity and good isolation rejection band.
Hybrid rendezvous clustering model for efficient data collection in multi sink based wireless sensor networks
Authors: M RAGHAVENDRA Y , B MAHADEVASWAMY U 
Published: June 2022

Abstract
Mobile sink based data collection has comparatively lower energy consumption compared to multi hop forwarding in wireless sensor networks. Energy efficiency is achieved by minimizing the hop count to sink in mobile sink based approaches. These approaches are of two types: Mobile sink collect stored data at rendezvous nodes or cluster heads forwarding data to mobile sink without storage by using its maximum transmission range. First approach provides higher energy gain at cost of delay. Second approach provides lower delay at cost of additional energy consumption. This work combines both the approaches with rendezvous node deciding to store or forward based on prediction of trajectory of multiple mobile sinks and packet latency deadlines.
MOVE in ROAD: Multi-Objective Vehicle Monitoring using River Formation Dynamics and Deep Learning Algorithms
Authors: Guravaiah Koppala , Dharavathu Niharika Naik , U Venkanna , Rangaraj Leela Velusamy 
Published: June 2022

Abstract

Nowadays, wireless sensor networks plays major role in solving vehicular Internet of Things (VIoT) applications. This paper address the common problems in vehicular technology such as unauthorized vehicular usage within a locality, vehicular thefts, and vehicular accidents using camera, radiofrequency identification (RFID) and Ultra-sonic sensors. It also addresses the problem of identifying the vehicle pollution parameter values such as carbon monoxide ( CO ) and carbon dioxide ( CO 2 ), providing information about alcohol consumption by driver, and checking validity (driving license) of the driver to drive the vehicle. The driver identification is going to be done with the help of driving license, which can be identified with the help of Deep learning algorithms such as MTCNN (Multi-Task Cascaded Convolutional Neural Networks) and facenet algorithms. The proposed system is deployed and demonstrated using Micro-controller, Micro-processor and other sensors in real time environment. The River Formation Dynamics based Multi-hop Routing Protocol for Vehicles (RFDMRPV) is used for communication between vehicles. Data collected from the sensors fixed in vehicles are transferred to server using RFDMRPV for storing and further processing.
Quality of Service Enhancement of Circular Microstrip Patch Antenna (CMPA) for 5G Communication Network
Authors: QAMAR SHAMIMUL , Rai Amrita , Roy Ajay , Prakash Om , Basha Syed Asif , Banu Firdouse , Mohammed Salman Arafath , Azeem Abdul 
Published: June 2022

Abstract
Due to small shape, compact size and easy fabrication, Microstip patch antennas (MPA) are prominently used in various domains and play a vital role in communication world. The characteristic disadvantage of the Microstip patch antenna (MPA) is its Narrow Bandwidth and low gain which is not suitable for 5G communication. To enhance the bandwidth and gain, a novel design of circular microstrip Patch antenna(CMPA) is proposed in this work. For overcome this problem it is tried to introduce a circular patch on FR-4 substrate material (_r = 4.4) also known as circular Microstip patch array, where the circular patch has a circular slot etched into it for wideband service. It has been designed and simulated with dielectric substrates (Rogers 5880) that have the dielectric constant of 2.2 with 1.5 mm height, using the High Frequency Structural Simulation (HFSSTM) tool, which is based on the Finite Element Method (FEM). The antenna has been design to work at 5.8GHz which solves the problem of narrow bandwidth. In addition to this proposed antenna gain also increase to 7.876 dB by introducing circular Microstrip patch, indicate that the gain of overall performance has been enhanced. The proposed antenna has been designed and tested for an operating frequency of 5.8GHz which is used for Wi-Fi communication and 5G networking all over the world.
Physico-chemical characteristics of biodegradable poly (lactic acid) and poly (lactic acid)/ chitosan composites under the influence of gamma irradiation
Authors: Elsawy Moataz A. , Fekry Mohamed , Sayed Aisha M. , Maziad Nabila A. , Saad Gamal R. 
Published: June 2022

Abstract
PLA and its nanocomposite containing 3% chitosan nanoparticles (PLA-3CsNP) were studied to see how γ -irradiation affected their characteristics. Different doses of γ -irradiation were applied to the investigated materials under inquiry (5–40 kGy) using 60Co at ambient condition. The irradiation materials were characterized by FT-IR, GPC, mechanical tensile test, DSC, XRD, and TGA in solid and chloroform solutions. The molecular weight of the studied materials was lowered when the irradiation dose was increased, indicating that γ-irradiation had the dominating effect through oxidative degradation, and chain scission. The addition of chitosan to PLA reduces the impact of γ-irradiation, while the samples irradiated in solution showed more degradation after irradiation than irradiated solid films. Irradiation caused a decrease in tensile strength and elongation at break values. Both the melting temperature (Tm) and the glass transition temperature (Tg) decreased as the irradiation dose was increased. The cold crystallization peak temperatures were reduced when pure PLA was irradiated in solution. The thermal stability of PLA was diminished as the irradiation dose was raised, and this effect was more pronounced in samples irradiated in chloroform solution.
Prevalence of Extended Spectrum Beta Lactamase and molecular detection of blaTEM, blaSHV and blaCTX-M genotypes among Gram Negative Bacilli Isolates from Pediatric Patient Population in Gaza strip
Authors: Aila Nabil El , Laham Nahed Al , Ayesh Basim 
Published: June 2022

Abstract
Background: Extended-spectrum β lactamases (ESBLs) have the ability to hydrolyze and cause resistance to types of the β-lactam antibiotics, including the extended-spectrum (or third generation) cephalosporins (e.g., cefotaxime, ceftriaxone, ceftazidime) and monobactams (e.g., aztreonam).Objectives: To assess the prevalence and molecular characteristics of ESBL producing Gram negative bacilli, isolated from a cohort of pediatric patients in Gaza hospitals.Methods: A total of 322 isolates of Gram-negative bacilli were collected from four referral pediatric hospitals in Gaza, namely: Al-Nasr, Al-Rantisi, Al-Durra and Beit Hanoun hospitals. These isolates were tested for ESBL production using the double disk synergy and CHROMagar phenotypic methods. Molecular characterization of the ESBL producing strains was performed using PCR targeting the CTX-M, TEM and SHV genes. The antibiotic profile was determined using the Kirby Bauer method according to the Clinical and Laboratory Standard Institute standards.Results: Out of 322 isolates tested by phenotypic methods, 166 (51.6%) were ESBL positive. The prevalence of ESBL production in Al-Nasr, Al-Rantisi, Al-Durra and Beit Hanoun hospitals was 54.0%, 52.5%, 45.5% and 52.8%, respectively. The prevalence of ESBL production among Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Acinetobacter spp., Proteus mirabilis, Enterobacter spp., Citrobacter spp., and Serratia marcescens was 55.3%, 63.4%, 17.8%, 57.1%, 33.3%, 28.5%, 38.4%, and 4.0%, respectively. ESBL production for urine, pus, blood, CSF and sputum was 53.3%, 55.2%, 47.4%, 33.3%, and 25%, respectively. Out of the 322 isolates, 144 were screened for CTX-M, TEM and SHV production. Using PCR, 85 (59%) was shown to be positive for at least one gene. The overall prevalence of CTX-M, TEM and SHV genes was 60.0%, 57.6%, and 38.3%, respectively.Meropenem and amikacin were the most effective antibiotics against the ESBLs producers (83.1% and 82.5% of susceptible isolates, respectively), while the least effective antibiotics were amoxicillin (3.1%) and cephalexin (13.9%). Moreover, ESBLs producers showed a high resistance rate to cefotaxime, ceftriaxone and ceftazidime (79.5%, 78.9% and 79.5%, respectively). Conclusion: Our results show high prevalence of ESBL production among Gram negative bacilli isolated from children in different pediatric hospitals in Gaza strip. A substantial level of resistance to first and second generation cephalosporins was also observed. This emphasizes the need for a rational antibiotic prescription and consumption policy.
Putting non-communicable disease data to work in Vietnam: An investigation of community health surveillance capacity
Authors: Nguyen T. Thu Nam , Nguyen T. Thi Tho , Tran Quoc Bao , Pham Cong Tuan , Perry Kelly E. , Haregu Tilahun , Oldenburg Brian , Kowal Paul 
Published: June 2022

Abstract
IntroductionDespite the public health system’s critical role in non-communicable disease (NCD) surveillance in Vietnam, limited evidence exists on the implementation of NCD surveillance activities within these systems and the need for capacity building across different system levels to meet expected NCD surveillance goals. This study aimed to evaluate the status of and describe factors affecting the implementation of NCD surveillance activities and to identify the NCD surveillance capacity building needs of the public health system in Vietnam.MethodsWe used a mixed-methods approach in four provinces, conducting self-completed surveys of staff from six Preventive Medicine Institutes (PHIs), 53 Centres for Disease Control (CDCs) and 148 commune health stations (CHS), as well as 18 in-depth interviews and 26 focus group discussions at four PHIs, four CDCs, and eight district health centres and CHS. ResultsStudy findings highlighted that although Vietnam has a well-functioning NCD surveillance system, a number of quality issues related to NCD surveillance data were salient. Multifactorial reasons were identified for incomplete, unconfirmed, and inaccurate mortality data and current disease surveillance data. Data on NCD management and treatment were reported to be of better quality than data for screening, targeted treatment, and counselling communication. Main factors affected the effective implementation of NCD surveillance, namely lack of complete and specific guidelines for NCD surveillance, limitations in human resource capacity within NCD departments, and shortage of funding for NCD surveillance activities. ConclusionStudy findings provide practical strategies for strengthening health system capacity for NCD surveillance through developing policies, guidelines, and standardised tools to guide NCD surveillance and a road map for integrated NCD surveillance, developing training packages and manuals for all levels of the health system, and conducting utilisation-focused surveillance training programs.
Nonconvulsive status epilepticus in Neurological ICU patients
Authors: Huang Yuanyuan , Yuan Dezhi , Hou Xianhua , Gui Li 
Published: June 2022

Abstract
Introduction: Nonconvulsive status epilepticus（NCSE）is a condition involving seizures without convulsions; it is usually characterized by altered consciousness and behavioral and vegetative abnormalities. Owing to the nonspecific symptoms, NCSE is often overlooked, especially in neurological intensive care unit(NICU) patients. Therefore, we investigated the etiology, clinical features, electroencephalographic (EEG) changes, treatment options, and outcomes of NCSE in NICU patients with altered consciousness.Methods: This study retrospectively collected the data of 20 patients with altered consciousness in the NICU. NCSE diagnoses were established by the treating neurologist who had been trained to recognize nonspecific clinical signs and recognize complex EEG changes.Results: We identified 20 patients(43.95±20.70 years) with clinical signs and EEG findings consistent with NCSE; 9 were female. All the patients suffered from altered consciousness. Five patients had established epilepsy. NCSE was attributed to acute pathological conditions. The underlying cause of NCSE was intracranial infection in 6 patients (30%), cerebrovascular disease in 5 patients(25%), irregular use of epilepsy drugs in 3 patients(15%), infection in 2 patients(10%), unknown in 3 patients, and immune-related inflammation in 1 patient. Fifteen patients had diffuse and five patients had temporal focal EEG abnormalities. Six of 20 NCSE cases (30%) resulted in death. All the patients, except for the patients who died, received anticonvulsant therapy and their altered conscious state was promptly altered.Conclusion: The clinical symptoms of NCSE without convulsions are often obscure and difficult to detect. NCSE can cause serious consequences and even death. Therefore, for patients with a high clinical suspicion of NCSE, continuous EEG monitoring is needed to quickly identify this condition and promptly start treat them.
Adjuvant treatment of Grade 4 Glioma, outcomes at a UK tertiary centre
Authors: Price Louise , Ziff Charlotte , Elmasry Abdelfattah , Giridharan Selvaraj 
Published: June 2022

Abstract
BackgroundThe 5 year overall survival (OS) for Glioblastoma (GBM) remains low. Our cohort had a lower percentage completing adjuvant treatment than those reported in trials. Therefore, we assess those not completing planned 6 cycles of adjuvant treatment and effect on survival outcomes. We also assess survival data for those who had Gliadel wafer insertion at the time of primary surgery. We go on to assess the combination of these factors on survival outcomes.MethodsWe carried out a retrospective cohort study of 110 patients who underwent neurosurgery followed by chemoradiotherapy (CRT) 60 Gray in 30 fractions and adjuvant Temazolomide (TMZ) from 2007 to 2016. We assessed OS and progression free survival (PFS) and carried out a number of subset analyses. ResultsOS was 16 months and PFS 11.9 months. 57% of patients completed 4-6 cycles of adjuvant TMZ 43% received 3 or less cycles of TMZ. Those unable to complete planned adjuvant TMZ had a poorer OS (10 vs 20 months, Cox analysis P-value 0.0003). Those who had maximal safe debulking plus Gliadel wafer insertion, median OS was improved, 19.5 months P=0.06. The group with the combination of significant factors, median OS was 2 months greater than those that did not receive Gliadel wafers and could not complete 4 cycles of adjuvant TMZ. ConclusionsSurvival outcomes were improved with Gliadel wafer insertion and completing 4-6 cycles of TMZ. Consequently the combination of these factors led to improved outcomes.
Sustaining a network by controlling a fraction of nodes
Authors: Sanhedrai Hillel , Havlin Shlomo 
Published: June 2022

Abstract
Multi-stability is a widely observed phenomenon in real complex networked systems, such as technological infrastructures, ecological systems, gene regulation, transportation and more. When a system functions normally but there exists also a potential state with abnormal low activity, although the system is at equilibrium it might make a transition into the low activity undesired state due to external disturbances and perturbations. Thus, such a system can be regarded as unsustainable, due to the danger of falling into the potential inactive state. Here we explore, analytically and by simulations, how supporting the activity of a fraction ρ of nodes can turn an unsustainable system to be sustainable by eliminating the inactive potential stable state. We thus unveil a new sustainability phase diagram in the presence of a fraction of controlled nodes ρ. This phase diagram could provide guidelines to sustain a network by external intervention and/or by strengthening the connectivity of the network.