bluuebunny/crossref_metadata_2025_split huggingface dataset:
The potential impact of the ketogenic diet on gut microbiota in the context of neurological disorders
Authors: Gudan Anna , Stachowska Ewa 
Published: June 2022

Abstract
One of the most important functional parts of a human intestinal tract is the microscopic intestinal barrier. Its function is to ensure the correct nutrient absorption and to protect against multiple pathogens, xenobiotics, and environmental toxins. Intestinal microbiota is an integral part of the intestinal epithelium. Human microbiota and their host interact with each other, both directly and indirectly, via multiple intermediates and metabolites. Some dietary fat that is not fully digested reaches the distal parts of the intestinal tract, where an interaction with gut microbiota takes place. Studies have shown that an animal-product based diet that provides a greater supply of saturated fat increases the number of bile-resistant microorganisms, including Bilophila. The total amount of Alistipes and Bacteroides is also increased. Long-term consumption of animal-based foods contributes to the formation of the enterotype described as the Bacteroides type. The ketogenic diet is mainly based on animal fats. The changes induced by this higher consumption of animal fats are associated with unfavorable metabolic changes. However, more and more research has shown evidence of the therapeutic properties of a ketogenic diet as far as neurodegenerative and metabolic diseases are concerned. Recent reports suggest that the protective effect of a ketogenic diet is highly dependent on the gut microbiota. This review focuses on the correlation between the influence of ketogenic diet on the intestinal microbiota changes observed while analyzing patients with diseases such as epilepsy, Alzheimer's disease, autism spectrum disorder, and multiple sclerosis.
Orwellian Opinions: The Language of Power and the Power of Language
Authors: Halper Thomas 
Published: June 2022

Abstract
In 1984 and other writings, George Orwell explored the language of power and the power of language. As illustrations of the abuses he identified, this essay analyzes a pair of famous constitutional opinions, Justice Brown's Plessy v. Ferguson and Justice Douglas’ Griswold v. Connecticut.
Partial budgeting for acquiring and operating a ground-based optical crop sensor for variable rate nitrogen application
Authors: Medel-Jiménez Francisco , Gronauer Andreas , Barta Norbert , Krexner Theresa , Neugschwandtner Reinhard W. , Kral Iris 
Published: June 2022

Summary
Optical crop sensors for variable rate nitrogen application (VRNA) are described as an optimal solution to increase yield while minimizing fertilizer costs, although their operation and acquisition costs could be high. In this study, a partial budgeting approach was used to assess the net income of buying and operating a crop sensor for VRNA for optimizing fertilizer application to winter wheat. Two VRNA scenarios – stimulus, where crops with lower yield expectations received more fertilizer, and compensatory, where crops with higher yield expectations received less fertilizer – were assessed and compared to a conventional way of fertilizer application. Both scenarios showed negative results. The stimulus scenario showed a yearly negative change in income of −227.3 €/ha/year on 25 ha of fertilized area and −38.9 €/ha/year on 250 ha of fertilized area. In the case of the compensatory scenario, a yearly change in income of −271.8 €/ha/year on 25 ha of fertilized area and −83.3 €/ha/year on 250 ha of fertilized area was achieved. Results also showed that bigger farms had lower losses than smaller farms due to the economy of scale. Farmers may opt for sharing or leasing the use of the crop sensor to reduce costs.
Ability of Three Pleurotus Species for Effective use of Giant Grass Compost
Authors: Niyimbabazi Obed , Nsanzinshuti Aimable , Hatungimana Mediatrice , Lin Hui , Zhang Lili , Lin Dongmei , Zhanxi Lin 
Published: June 2022

Abstract

Pennisetum sinese is a giant grass with a fast-growing and high rooting rate, high sugar, protein content, and high biomass yield, which causes it to be an efficient and economic energy crop of high productivity, application in phytoremediation, and fodder production. The composting system of this grass that is adapted to the simplest formulation is easy and economically feasible in small farms for cultivating oyster mushrooms. In this study, giant grass compost was employed as a substrate for cultivating three Pleurotus species: P. florida, P. pulmonarius, and P. ostreatus to assess their enzyme activities, growth, and yields. Lignin peroxidase (LiP) was the most active enzyme in each species, while other enzymes were differently expressed between species and developmental phases. The average mass of fruiting bodies formed on the giant grass compost was 173.4 g, 166.5 g, and 152.2 g. The biological effectivity was 82.6%, 78.6%, and 72.5% for P. pulmonarius, P. ostreatus, and P. florida, respectively. The obtained results indicate the usefulness of giant grass compost for the cultivation of the three studied Pleurotus species.
Normal tissue objective (NTO) tool in Eclipse treatment planning system for dose distribution optimization
Authors: Indrayani Liza , Anam Choirul , Sutanto Heri , Subroto Rinarto , Dougherty Geoff 
Published: June 2022

Abstract

Introduction: The purpose of this study was to determine the best normal tissue objective (NTO) values based on the dose distribution from brain tumor radiation therapy.

Material and methods: The NTO is a constraint provided by Eclipse to limit the dose to normal tissues by steepening the dose gradient. The multitude of NTO setting combinations necessitates optimal NTO settings. The Eclipse supports manual and automatic NTOs. Fifteen patients were re-planned using NTO priorities of 1, 50, 100, 150, 200, and 500 in combination with dose fall-offs of 0.05, 0.1, 0.2, 0.3, 0.5, 1 and 5 mm-1. NTO distance to planning target volume (PTV), start dose, and end dose were 1 mm, 105%, and 60%, respectively, for all plans. In addition, planning without the NTO was arranged to find out its effect on planning. The prescription dose covered 95% of the PTV. Planning was evaluated using several indices: conformity index (CI), homogeneity index (HI), gradient index (GI), modified gradient index (mGI), comprehensive quality index (CQI), and monitor unit (MU). Differences among automatic NTO, manual NTO, and without NTO were evaluated using the Wilcoxon signed-rank test.

Results: Comparisons obtained without and with manual NTO were: CI of 0.77 vs. 0.96 (p = 0.002), GI of 4.52 vs. 4.69 (p = 0.233), mGI of 4.93 vs. 3.95 (p = 0.001), HI of 1.10 vs. 1.10 (p = 0.330), and MU/cGy of 3.44 vs. 3.42 (p = 0.460). Planning without NTO produced a poor conformity index. Comparisons of automatic and manual NTOs were: CI of 0.92 vs. 0.96 (p = 0.035), GI of 5.25 vs. 4.69 (p = 0.253), mGI of 4.46 vs. 3.95 (p = 0.001), HI of 1.09 vs. 1.10 (p = 0.004), MU/cGy of 3.31 vs. 3.42 (p = 0.041).

Conclusions: Based on these results, manual NTO with a priority of 100 and dose fall-off 0.5 mm-1 was optimal, as indicated by the high dose reduction in normal tissue.
Implementasi Program Naval Base Open Day (NBOD) Di Komando Armada II
Authors: Cahyanto Indra Dwi 
Published: June 2022

Salah satu metode komunikasi sosial TNI adalah dengan melibatkan masyarakat dalam kegiatan yang dilaksanakan oleh TNI termasuk pada program NBOD ini, dimana masyarakat dilibatkan baik sebagai peserta lomba, bagian dari pelaksana, maupun hanya sebagai pengunjung. Sehingga dalam program ini terdapat kebersamaan sipil - militer saja seeara fisik, tetapi juga emosional karena dalam kegiatan yang sama. Namun setelah bertahun-tahun, pelaksanaan program NBOD ini, perlu dilakukan pengembangan kegiatan sehingga dapat memebrikan manfaat yang lebih lagi masyarakat
Tujuan dari penelitian ini adalah untuk menyajikan dan mendiskripsikan: (i) implentasi program NBOD, (ii) faktor - faktor yang mempengaruhi implementasi tersebut, dan (iii) Strategi pengembangan program NBOD di Koarmada IIkedepan.Penelitian ini menggunakan pendekatan kualitatif eksplanasi dengan menggunakan teori implementasi George Edaward III. Hasil penelitian menunjukkan: vaiabel: komunikasi, sumber daya, disposisi dan struktur birokrasi memberikan dukungan yang positif, sehingga program dapat terlaksana sesuai dengan rencana kegiatan. Faktor - faktor pendukungProgram ini adalah dukungan kebijakan, anggaran, semangat / disiplin implementor, fasilitas dan materi Koarmatim serta dukungan masyarakat baik sebagai kelompok sasaran program maupun sebagai bagian dari implementor.Sedangkan faktor penghambatnya adalah anggaran pemerintah dan kepadatan lalu lintas selama pelaksanaan program NBOD.Strategi pengembangan program NBOD kedepan di Koarmada II adalah penambahan kegiatan - kegiatan berupa: Bhakti TNI, Bintahwil (Pembinaan Ketahanan Wilayah), Joy Sailing , Sailing Pass , lomba - lomba berbasis kemaritiman, seminar dan pelatihan praktis pemberdayaan masyarakat pesisir dan peningkatan kolaborasi Koarmatim dengan badan usaha dalam pelaksanaan program NBOD.
Strategi Komunikasi Pemerintah Desa Sebagai Langkah Taktis Penanganan Dan Pencegahan Covid-19
Authors: Gamaputra Gading , Prasetyawan Agus , Isbandodo Prasetyo , Lestari Yuni , Putri Alvionita Fitria , Hidayatullah M Syarif , Noviyanti Noviyanti 
Published: June 2022

Abstract
The Tuban Regency Government issued a Regent Decree No. 440/1592/414.103/2020 concerning Increased Awareness of Covid-19 in Tuban Regency. All villages in Tuban Regency are required to carry out a program of handling and preventing Covid-19 activities. Covid-19 handling and prevention The Kesamben Village Government is experiencing problems, including the public's distrust of the dangers of Covid-19 due to lack of accurate data, information and low public trust regarding the handling of COVID-19 in Indonesia. To overcome this problem, the Kesamben Village Government carried out a communication strategy to the community so that the implementation and handling of Covid-19 activities were carried out properly and became a pilot village for handling COVID-19 in Tuban Regency. The research used in this research is descriptive qualitative by focusing on the first, the tactical steps of the Kesamben Village Government in the Prevention and Handling of Covid-19. Second, the communication strategy for the prevention and handling of Covid- 19

Keywords: Corona Virus Disease 2019 (covid-19), Village Government Communication Strategy.
INVENTARISASI JAMUR MAKROSKOPIS DI HUTAN LINDUNG BUKIT PENINTIN KABUPATEN MELAWI
Authors: Widyastuti Desinta Ayu , Yeni Laili Fitri 
Published: June 2022

A B S T R A C TMacroscopic mushrooms research in this study aims to find the types of macroscopic mushrooms found in the protected forest of bukit penintin melawi regency. Based on the results of the inventory conducted there are as many as 53 types of macroscopic fungi from 19 familles found to come from 2 many as 5 types of 2 famillies namely the family Sarcoscyphaceae and family Xylariaceae while from the phyllum Basidiomycota found as many 17 famillies with the most found namely in the family Polyporaceae ass many as 12 types while the least is the family Clavariaceae, Schizophyllaceae, Ganodermataceae, Meripilaceae, Meruliaceae, Dacrymycataceae, and Lyophyllaceae which each found only 1 type of macroscopic fungus. It is known that mushrooms are found to have the potential as food ingredients, drugs, as dekomposer and have dangerous toxic content. Kata Kunci: Macroscopic mushrooms, Ascomycota, Basidiomycota,
Fatigue Life Assessment of Sideboard on Deck Barge Using Finite Element Methods
Authors: Alam Alamsyah , Wulandari Amalia Ika , Oktavaro Nugroho Septianda , Pawara M Uswah , Riyadi Muhammad 
Published: June 2022

A Deck barge is a type of ship that has a flat hull used to transport large amounts of cargo such as wood, coal, sand, etc. The deck barge uses retaining walls to transport bulk loads on deck known as sideboards which can collapse due to fatigue life. The purpose of this research is to determine the maximum stress and fatigue life of the sideboard construction based on the height of the bulk load on the sideboard using coal as the bulk load. The method used in this research is the finite element method with a high load case of coal loading to the sideboard is 2.24 m, 2.60 m, and 2.96 m. The results showed that a high load case of 2.24 m detected a maximum stress value of 79.25 MPa and a fatigue life of 81.16 years with 10 x 105 cycles. Load case with a high load of 2.60 m detected a maximum stress value of 110.11 MPa and a fatigue life of 24.72 years with 3.53 x 105 cycle. For a high load case of 2.96 m, a maximum stress value of 146.80 MPa was detected and a fatigue life of 9.28 years with 2 x 105 cycle. There is an increasing stress value by the rise of the load height against the sideboard and there is a decrease in the fatigue life in the construction.
PENGELOLAAN KEUANGAN DAN PENERAPAN STRATEGI DIGITAL MARKETING BAGI UMKM TERDAMPAK PANDEMI COVID – 19
Authors: Indriani Eni , Kartikasari Nungki , Nabila D. Tiallura Dela 
Published: June 2022

Pandemi Covid-19 membawa dampak pada penurunan daya beli masyarakat yang disebabkan oleh pertumbuhan ekonomi dan perputaran uang yang masih terhambat oleh pandemi, sementara penawaran produk semakin tinggi dimasyarakat yang dipicu oleh tumbuhnya usaha baru yang menyebabkan tingginya persaingan dalam usaha sejenis. Permasalahan lain yang juga tidak kalah penting adalah terkait dengan pengelolaan usaha terutama pengelolaan keuangan yang baik, karena usaha yang telah berkembang tentunya perlu dikelola secara baik dan professional melalui suatu system tata kelola yang baik. Permasalahan yang dihadapi oleh pelaku UMKM terdampak Pandemi Covid – 19, salah satunya UMKM Dapur Jati Rasa yang berlokasi di Desa Jatisela Kecamatan Gunung Sari – Lombok Barat, saat ini terkait dengan pengelolaan keuangan dan strategi pemasaran akan dibantu penyelesainnya oleh Tim Pengabdian pada Masyarakat FEB Unram melalui kegiatan Pelatihan dan Pendampingan tentang Pengelolaan Keuangan dan Penerapan Strategi Digital Marketing. Kegiatan PPM pelatihan dan pendampingan pengelolaan keuangan dan pemasaran digital berjalan sangat baik dengan ketercapaian target materi yang baik, dimana mitra telah mampu mengelola akun media sosialnya sebagai media pemasaran.
WORKSHOP PEMANFAATAN APLIKASI BERBASIS WEB SEBAGAI MEDIA EVALUASI PEMBELAJARAN JARAK JAUH BAGI GURU DI SDN 2 GOLONG
Authors: Husniati Husniati , Widodo Arif , Haryati Linda Feni , Rosyidah Awal Nur Kholifatur , Anar Ashar Pajarungi 
Published: June 2022

Pembelajaran jarak jauh yang dilakukan selama pandemi masih banyak menghadapi masalah. Tidak hanya dalam proses pembelajaran tetapi juga berkaitan dengan evaluasi hasil belajar siswa. Terlebih lagi pada jenjang Sekolah Dasar, penggunaan model pembelajaran jarak jauh memiliki kesulitan tersendiri. Kondisi semacam inilah yang dialami oleh sekolah mitra di SDN 2 Golong Narmada Lombok Barat. Sejumlah guru mengalami kendala dalam melakukan evaluasi pembelajaran jarak jauh, baik pembelajaran daring maupun luring. Para guru terkendala dengan keterbatasan penggunaan media evaluasi, terutama media yang berbasis online. Media evaluasi yang digunakan masih terbatas pada paper test yang dilakukan secara manual. Media evaluasi berbasis paper test tidak efektif digunakan dalam pembelajaran jarak jauh. Proses evaluasi yang dilakukan tidak berjalan secara maksimal. Implikasinya adalah perkembangan kemampuan akademik terutama hasil belajar siswa selama pembelajaran jarak jauh tidak dapat dipantau. Kondisi semacam ini perlu mendapat perhatian agar pelaksanaan evaluasi hasil belajar selama pandemi dapat berjalan optimal. Berawal dari permasalahan tersebut, perlu diadakan workshop tentang pemanfaatan aplikasi berbasis web sebagai bentuk media evaluasi pembelajaran jarak jauh bagi guru. Workshop tersebut didesain dalam bentuk kegiatan pengabdian pada masyarakat yang dilaksanakan secara tatap muka langsung. Tahapan pertama merupakan pelatihan yang mencakup teori, sementara tahap kedua adalah praktik pembuatan soal evaluasi degan pemanfaatan aplikasi pembelajaran berbasis web yaitu google form dan quizizz. Hasil dari kegiatan ini adalah menambah wawasan dan peningkatan kompetensi guru dalam melakukan evaluasi penilaian pada pembelajaran jarak jauh menggunakan aplikasi bebasis web.
An empirical examination of the Impact of Initial Capital, Prior Experience, and R&D on SMEs’ Survival and Economic Performance: Moderating Role of Innovation Culture
Authors: Bokhari Syed Asad Abbas 
Published: June 2022

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<strong>Abstract </strong>
<p>SMEs’ survival and performance continue to be a central concern for strategy experts. There are numerous factors that affect the SMEs’ survival for new entrants in the industry. This study incorporates research on the survival and performance of new entrant SMEs in a relationship with initial capital investment, experience, R&D, and innovation culture. We examined the influence of the SMEs’ initial investment, experience, R&D, and innovation culture on its survival and performance guided by the evolutionary model of entry and exit to conclude whether these are positively related to each other. Further, we investigated moderated role of innovation culture between initial capital, experience, R&D, and firm performance. The outcomes of this study established on a large size sample of 337 SMEs suggest that firms with a large initial investment, prior experience, and R&D have higher probabilities of survival and economic performance and innovation culture strengthens the relationship between predictor and outcome constructs.</p>
Perioperative Pain Management With Bilateral Pecto-intercostal Fascial Block in Pediatric Patients Undergoing Open Cardiac Surgery
Authors: Zhang Yang , Min Jia , Chen Shibiao 
Published: June 2022

PurposesPediatric open cardiac surgical patients usually suffer from acute pain after operation. The current work aimed to explore the impact of bilateral PIFB in children suffering from open cardiac surgery.MethodsThis work randomized altogether 110 child patients as bilateral PIFB (PIF) and non-nerve block (SAL) groups. This work adopted post-operative pain at exercise and rest statuses as the primary endpoint, whereas time-to-drain removal/extubation/initial defecation, intraoperative/post-operative fentanyl use, and length of ICU and hospital stay as the secondary endpoints.ResultsMOPS were significantly higher at 24-h post-operatively at coughing and rest statuses in SAL group compared with PIF group. Meanwhile, PIF group exhibited markedly lower intraoperative/post-operative fentanyl use amounts, as well as markedly reduced time-to-extubation/initial flatus, and length of ICU/hospital stay.ConclusionBilateral PIFB in pediatric open cardiac surgical patients provide effective analgesia and lower the length of hospital stay.
The U-Shaped Relationship Between Serum Uric Acid and Long-Term All-Cause Mortality in Coronary Artery Disease Patients: A Cohort Study of 33,034 Patients
Authors: Zheng Yiying , Ou Jiaman , Huang Dehua , Zhou Ziyou , Dong Xiaoli , Chen Jie , Liang Dandan , Liu Jin , Liu Yong , Chen Jiyan , Huang Xiaoyu , Tan Ning 
Published: June 2022

BackgroundAssociations between high serum uric acid (SUA) and cardiovascular diseases have been reported. However, few studies have been conducted to explore the relationship between SUA and long-term all-cause mortality in coronary artery disease (CAD) patients. Our study aims to investigate the relationship between SUA and long-term all-cause mortality in patients with CAD.MethodsFrom January 2007 to December 2018, we divided 33,034 patients with CAD admitted in the Guangdong Provincial People's Hospital into five groups (quintile 1: SUA &lt;5.05 mg/dl, quintile 2: 5.05 mg/dl ≤ SUA &lt;5.59 mg/dl, quintile 3:5.59 mg/dl ≤ SUA &lt;6.8 mg/dl, quintile 4, 6.8 mg/dl ≤ SUA &lt;7.93 mg/dl, and quintile 5, SUA ≥7.93 mg/d;). This study used Kaplan–Meier survival analysis to evaluate patient outcomes with different ranges of SUA. Cox proportional hazards regression models and restricted cubic spline were applied to determine the association between serum uric and long-term all-cause mortality.ResultsA total of 33,034 participants were recruited, including 24,780 (75.01%) men and 8,254 (24.99) women in this cohort study. Median follow-up was 4.91 years. We found that SUA is an independent risk factor of long-term all-cause mortality according to the result of Cox proportional hazards models. This study also illustrated an approximate U-shape association between SUA and all-cause mortality when compared with 5.95 mg/lL ≤ SUA &lt;6.8 mg/dl, SUA &lt;5.0 5mg/dl (adjusted hazard ratio (aHR) =1.13, 95% CI: 1.01–1.26, p = 0.03), and SUA ≥8 mg/dL (aHR = 1.18, 95% CI: 1.06-1.32, p = 0.003).ConclusionOur study indicated a U-shaped relationship between SUA and long-term all-cause mortality in patients with CAD. No matter whether SUA is too high or too low, it increased the all-cause mortality in the CAD population, which deserves to be closely monitored.
A Comparison of the Geochemical Characteristics of Ultra-Deep Natural Gas in the Kuqa Foreland and Marine Craton Areas in the Tarim Basin, China
Authors: Yu Cong , Ni Yunyan , Dai Jinxing , He Yuanyuan , Fang Chenchen , Liao Fengrong 
Published: June 2022

This research analyzed the composition and hydrocarbon isotope geochemical characteristics of ultra-deep natural gas (buried deeper than 6000 m) in more than 130 wells in the Tarim Basin. Characteristics of the ultra-deep natural gas components in the Tarim Basin are as follows: natural gas in the Kuqa sandstone reservoir is developed as dry gas, with a high methane content (an average of 95.53%) and a low ethane content (an average of only 1.39%). The ultra-deep gas of the marine craton carbonate reservoirs in the North Tarim-Central Tarim-East Tarim area is developed as wet gas. It is mainly composed of methane ranging from 56.1% to 98.8%, with an average content of 76.36% and also contains a small amount of ethane amounting to 6.74%. CO2 and H2S contents of ultra-deep condensate gas in the Central Tarim area are high, with maximum values of 24.2% and 23.1%, respectively. Isotopic characteristics are as follows: δ13C1 values of Kuqa natural gas are distributed between −36‰ and −25.3‰, with an average of −28.2‰, δ13C2 values are distributed between −26.2‰ and −13.8‰, with an average of −18.3‰. Most gas samples in Kuqa area are developed with the reversal of carbon isotopic series as δ13C2 &gt; δ13C3, and the δ13CCO2 values are distributed between −19.5‰ and −10.3‰. The δ13C1 values of ultra-deep gas in marine craton carbonate rocks are distributed between −54.4‰ and −33.3‰, with an average of −42.6‰. δ13C2 values are distributed between −41.1‰ and −29.4‰, with an average of −33.8‰, and δ13CCO2 values are distributed between −28.2‰–0.6‰. According to the identification chart, it can be seen that the ultra-deep gas in the sandstone reservoir of the Kuqa foreland is mainly coal-derived gas in the high over-mature stage, and the reversal of carbon isotopic series may be caused by the mixing of natural gas of the same type and different sources. The natural gas in carbonate reservoirs of marine craton is mainly oil-type gas with complex sources, including both kerogen cracking gas and oil cracking gas. CO2 can be formed by organic and inorganic genesis. Inorganic CO2 is most likely to be generated by the dissolution of carbonate rocks under acid formation water.