bluuebunny/crossref_metadata_2025_split huggingface dataset:
PP43 Line manager knowledge and concerns when managing female staff during the menopause transition in one UK ambulance service
Authors: Foster Theresa , Prothero Larissa , Mochrie Tessa 
Published: August 2022

BackgroundMenopausal symptoms can have a significant effect on workplace attendance and performance, yet limited evidence regarding the impact of menopause transition in the emergency services exists.Previous service evaluation activity in one UK ambulance Trust identified scope for improving staff health and wellbeing during the menopause transition and led to development of national research currently underway. One of the research aims was to understand line manager knowledge and concerns when managing female staff during the menopause transition.MethodsFollowing self-consent, a purpose-designed, online, anonymous, 17-question survey, was developed to understand line manager demographics (age, gender, time in managerial role, number of staff managed, function within Trust), access to menopause transition training and policy, whether they felt comfortable talking about the menopause and managing staff in menopause transition, views about the key work issues and key health concerns of menopausal female staff, and their own key concerns when managing such staff across all functions of one UK ambulance service.The research also sought to explore recommendations for service improvements that could better support managers with staff experiencing the menopause. This research commenced in December 2021 with the survey due to close after 30 days. The responses are due to be analysed using quantitative (descriptive) and qualitative (thematic) approaches.ResultsThis research is in progress but not complete. However, quantitative data analysis will be completed by end of January 2022, including a description of respondent characteristics, and respective knowledge, concerns, and issues. High-level qualitative themes are anticipated to be extracted by end of February 2022 in time for presentation at the conference.ConclusionsThe findings of this novel research will provide insight to the impact of the menopause transition on those in a line manager role within the prehospital ambulance setting and identify initiatives for further research or service development activity.
06 Cardiovascular disease on the frontline: 999 staff at risk?
Authors: Passmore Rin , Jordan Rachel 
Published: August 2022

BackgroundThere is mounting global evidence that Emergency Medical Service (EMS) staff are at significant risk of poor health outcomes due to the complex interaction between occupational risk factors and unhealthy lifestyle behaviours. Shift workers are known to have an increased risk of cardiovascular disease and are more likely to have a cardiovascular event. Specifically, EMS staff are prone to hypertension, dyslipidemia and being overweight or obese. UK ambulance trusts do not routinely monitor the physical health of their staff and there is no UK data to quantify the cardiovascular risk to staff. This study aims to measure cardiovascular risk in UK EMS staff and to explore any association between cardiovascular risk and occupational risk factors specific to this unique workforce.MethodsThis will be a cross-sectional study using frontline staff from a UK ambulance trust. A sample of 400 participants will be recruited to have their 10yr cardiovascular disease risk calculated using a validated tool (QRISK2) using clinical history, BMI and biochemistry. In addition, participants’ occupational risk factors such as role, shift type and length of service, as well as their independent cardiovascular risk factors such as physical activity and dietary intake will be captured. Data from participants who have had a cardiovascular event(s) will also be measured.ResultsQRISK2 score will be analysed as the primary outcome. Secondary outcomes include incidence of self-reported cardiovascular events, individual cardiovascular risk factors and the association between cardiovascular and occupational risk factors. Participants will receive feedback on their results should they opt for this.ConclusionsIt is hoped that the results of this study could be used to enable the development of national health initiatives for EMS staff with future recommendations for effective targeted health interventions to promote a healthy workforce.
Establishment and validation of prognostic nomograms integrating histopathological features in patients with endocervical adenocarcinoma
Authors: Luo Rong-Zhen , Yang Xia , Zhang Shi-Wen , Liu Li-Li 
Published: August 2022

AimsTo develop and verify pathological models using pathological features basing on HE images to predict survival invasive endocervical adenocarcinoma (ECA) postoperatively.MethodsThere are 289 ECA patients were classified into training and validation cohort. A histological signature was produced in 191 patients and verified in the validation groups. Histological models combining the histological features were built, proving the incremental value of our model to the traditional staging system for individualised prognosis estimation.ResultsOur model included five chosen histological characteristics and was significantly related to overall survival (OS). Our model had AUC of 0.862 and 0.955, 0.891 and 0.801 in prognosticating 3-year and 5 year OS in the training and validation cohort, respectively. In training cohorts, our model had better performance for evaluation of OS (C-index: 0.832; 95% CI 0.751 to 0.913) than International Federation of Gynecology and Obstetrics (FIGO) staging system (C-index: 0.648; 95% CI 0.542 to 0.753) and treatment (C-index: 0.687; 95% CI 0.605 to 0.769), with advanced efficiency of the classification of survival outcomes. Furthermore, in both cohorts, a risk stratification system was built that was able to precisely stratify stage I and II ECA patients into high-risk and low-risk subpopulation with significantly different prognosis.ConclusionsA nomogram with five histological signatures had better performance in OS prediction compared with traditional staging systems in ECAs, which might enable a step forward to precision medicine.
Study of common hypertriglyceridaemia genetic variants and subclinical atherosclerosis in a group of women with SLE and a control group
Authors: Fanlo-Maresma Marta , Esteve-Luque Virginia , Pintó Xavier , Padró-Miquel Ariadna , Corbella Emili , Candás-Estébanez Beatriz 
Published: August 2022

ObjectiveSLE is associated with increased cardiovascular risk (CVR). High serum concentrations of triglyceride-rich lipoproteins and apolipoprotein B-rich particles constitute the characteristic dyslipidaemia of SLE.MethodsA cross-sectional study was conducted to study the relationship between genetic variants involved in polygenic hypertriglyceridaemia, subclinical atherosclerosis and lipoprotein abnormalities. 73 women with SLE and 73 control women age-matched with the case group were recruited (age range 30–75 years). Serum analysis, subclinical atherosclerosis screening studies for the detection of plaque, and genetic analysis of theAPOE,ZPR1,APOA5andGCKRgenes were performed.ResultsTriglyceride concentrations and the prevalence of hypertension, dyslipidaemia and carotid atherosclerosis were higher in women with SLE than in the control group. Multivariate logistic regression showed that CC homozygosity for theGCKRrs1260326 gene (OR=0.111, 95% CI 0.015 to 0.804, p=0.030) and an increase of 1 mmol/L in triglyceride concentrations were associated with a greater risk of carotid plaque in women with SLE (OR=7.576, 95% CI 2.415 to 23.767, p=0.001).ConclusionsGCKRCC homozygosity (rs1260326) and serum triglyceride concentrations are independently associated with subclinical carotid atherosclerosis in women with SLE. Subclinical carotid atherosclerosis is also more prevalent in these women compared with the control group. The study ofGCKRrs1260326 gene variants may contribute to more precise assessment of CVR and modulation of the intensity of lipid-lowering treatment in patients with SLE.
Pair-production of the charged IDM scalars at high energy CLIC
Authors: Klamka Jan , Żarnecki Aleksander Filip 
Published: August 2022

AbstractThe Inert Doublet Model (IDM) is a simple extension of the Standard Model, introducing an additional Higgs doublet that brings in four new scalar particles. The lightest of the IDM scalars is stable and is a good candidate for a dark matter particle. The potential of discovering the IDM scalars in the experiment at the Compact Linear Collider (CLIC), an$$e^{+}e^{-}$$e+e-collider proposed as the next generation infrastructure at CERN, has been tested for two high-energy running stages, at 1.5 TeV and 3 TeV centre-of-mass energy. The CLIC sensitivity to pair-production of the charged IDM scalars was studied using the full detector simulation withGeant4for selected high-mass IDM benchmark scenarios and the semi-leptonic final state. To extrapolate full simulation results to a wider range of IDM benchmark scenarios, the CLIC detector model defined in theDelphesfast simulation framework was modified to take into account the$$\gamma \gamma \rightarrow $$γγ→had. beam-induced background. Results of the study indicate that heavy charged IDM scalars can be discovered at CLIC for most of the considered benchmark scenarios, up to masses of the order of 1 TeV.
Virtual neutrino propagation at short baselines
Authors: Naumov Vadim A. , Shkirmanov Dmitry S. 
Published: August 2022

AbstractWithin a covariant perturbative field-theoretical approach, the wave-packet modified neutrino propagator is expressed as an asymptotic expansion in powers of dimensionless Lorentz- and rotation-invariant variables. The expansion is valid at high energies and short but macroscopic space-time distances between the vertices of the proper Feynman macrodiagram. In terms of duality between the propagator and the effective neutrino wave packet, at short times and distances, neutrinos are deeply virtual and move quasi-classically. In the lowest-order approximation, this leads to the classical inverse-square dependence of the modulus squared flavor transition amplitude and related neutrino-induced event rate from distance L between the source and detector, and the above-mentioned asymptotics results in the corrections to the classical behavior represented by powers of $$L^2$$

L
2

. This is very different from the long-baseline regime, where similar corrections are given by an asymptotic expansion in inverse powers of $$L^2$$

L
2

. However, in both short- and long-baseline regimes, the main corrections lead to a decrease in number of neutrino events.
An overview of geological carbon sequestration and its geomechanical aspects
Authors: Babarinde Oladipupo , Schwartz Brandon , Meng Jingyao , Kim Seunghee , Segura José M. , Schultz Richard A. , Soroush Hamed 
Published: August 2022

Abstract

Carbon capture and sequestration (CCS) is widely recognized as an important component of technological approaches to directly address carbon dioxide (CO
2
) emissions. The geological sequestration aspect of CCS requires careful site selection and assessment of processes when planning a CCS project, including coupled fluid flow–thermal–geochemical–geomechanical phenomena. In this paper, we present a high-level overview of carbon capture utilization and sequestration (CCUS): the geological sequestration aspect, global projects/facilities, regulatory framework and financial incentives for CCUS. We review the current research areas in geomechanics (including pore pressure–stress coupling, fault reactivation and caprock integrity) associated with geological CO
2
sequestration and discuss the role of rock physics in monitoring, verification and accounting activities. Finally, we suggest research needs that are critical to facilitating the deployment of CCS and improving geomechanical assessments of CO
2
sequestration sites.
Developing a new innovative methodology to integrate geophysical techniques into characterization of potential CO
2
storage sites: Lopín structure (southern Ebro Basin, Spain)
Authors: Ayala C. , Benjumea B. , Mediato J. F. , García-Crespo J. , Clariana P. , Soto R. , Rubio F. , Rey-Moral C. , Pueyo E. L. , Martín-León J. , García A. G. , Fernández-Canteli P. , Martínez-Orio R. 
Published: August 2022

Abstract

One of the main challenges facing geological storage is to identify cost-effective methodological workflows for characterizing and monitoring geological storage sites. In the framework of the ALGECO2 project, led by the IGME (Geological and Mining Institute, Spain), a preliminary study of the Lopín site in the NE of Spain indicated conditions were promising for geological storage of CO
2
. However, the poor quality of the legacy seismic reflection data precluded thorough characterization. Within the H2020 PilotSTRATEGY project, one of the possible selected target reservoirs was the Lopín structure. In order to characterize its geometry and physical properties as required to properly evaluate its storage potential, IGME applied a new emerging methodology that integrates reinterpreted reflection seismic data with newly acquired and interpreted gravity, passive seismic and petrophysical data. This methodology was successfully applied along one seismic profile. In this paper, we present the results of this integration as the first step towards characterizing the site and evaluating its suitability for storage.
Alteplase for Stroke With Unknown Onset Time in Chronic Kidney Disease: A Pooled Analysis of Individual Participant Data
Authors: Miwa Kaori , Koga Masatoshi , Jensen Märit , Inoue Manabu , Yoshimura Sohei , Fukuda-Doi Mayumi , Boutitie Florent , Ma Henry , Ringleb Peter A. , Wu Ona , Schwamm Lee H. , Warach Steven , Hacke Werner , Davis Stephen M. , Donnan Geoffrey A. , Gerloff Christian , Thomalla Götz , Toyoda Kazunori , Cheng Bastian , Bendszus Martin , Bladin Christopher , Churilov Leonid , Campbell Brunce , Parsons Mark , Yassi Nawaf , Ebinger Martin , Endres Matthias , Fiebach Jochen B. , Kleinig Timothy , Latour Lawrence , Lemmens Robin , Levi Christopher , Leys Didier , Molina Carlos , Muir Keith , Nighoghossian Norbert , Pedraza Salvador , Schellinger Peter D. , Schwab Stefan , Simonsen Claus Z. , Song Shlee S. , Thijs Vincent , Toni Danilo , Hsu Chung Y. , Wahlgren Nils 
Published: August 2022

Background:
Although chronic kidney disease (CKD) is associated with worse stroke outcomes, data regarding the influence of CKD on intravenous thrombolysis outcomes are scarce. We sought to assess the efficacy and safety of intravenous thrombolysis for acute ischemic stroke with unknown onset time in patients with CKD.

Methods:

Patients with an acute stroke of unknown onset time from the EOS trials (Evaluation of Unknown Onset Stroke Thrombolysis) collaboration were evaluated using an individual patient-level database of randomized controlled trials comparing intravenous thrombolysis with placebo/standard treatment. CKD was defined as baseline estimated glomerular filtration rate of <60 ml/min/1.73m
2
Mixed-effect logistic-regression analysis was performed to evaluate treatment effects. A favorable outcome was defined as a modified Rankin Scale score of 0 to 1 at 90 days. Safety outcomes were symptomatic intracranial hemorrhage at 22 to 36 hours and 90-day mortality.

Results:

Baseline data on renal function were available for 688 of 843 patients. Of these, CKD was present in 146 (21%), including 69 of 351 patients receiving alteplase and 77 of 337 patients receiving placebo/standard treatment. Overall, treatment with alteplase was associated with higher odds of favorable outcome, and CKD did not modify the treatment effect (
P
interaction
=0.834). A favorable outcome was observed in 31 of 69 (46%) patients with CKD in the alteplase group and in 28 of 77 (36%) patients with CKD in the control group (adjusted odds ratio, 1.19 [95% CI, 0.55–2.58]). Among patients with CKD, symptomatic intracranial hemorrhage occurred in 2 patients (3%) in the alteplase group but in none of the controls (
P
=0.133). At 90 days, death was reported in 3 patients (4%) in the alteplase group compared with 2 patients (3%) in the controls (
P
=0.539).

Conclusions:
The present analysis indicates that the benefit of alteplase does not differ between stroke patients with unknown onset time with and without CKD, although the statistical power was lacking to confirm the efficacy in subgroups. This study only applies to mild-to-moderate or predialysis CKD.
How Much Does Lookahead Matter for Disambiguation? Partial Arabic
Diacritization Case Study
Authors: Esmail Saeed , Bar Kfir , Dershowitz Nachum 
Published: August 2022

Abstract
We suggest a model for partial diacritization of deep orthographies. We focus on Arabic, where the optional indication of selected vowels by means of diacritics can resolve ambiguity and improve readability. Our partial diacritizer restores short vowels only when they contribute to the ease of understandability during reading a given running text. The idea is to identify those uncertainties of absent vowels that require the reader to look ahead to disambiguate. To achieve this, two independent neural networks are used for predicting diacritics, one that takes the entire sentence as input and another that considers only the text that has been read thus far. Partial diacritization is then determined by retaining precisely those vowels on which the two networks disagree, preferring the reading based on consideration of the whole sentence over the more naïve reading-order diacritization.
For evaluation, we prepared a new dataset of Arabic texts with both full and partial vowelization. In addition to facilitating readability, we find that our partial diacritizer improves translation quality compared either to their total absence or to random selection. Lastly, we study the benefit of knowing the text that follows the word in focus toward the restoration of short vowels during reading, and we measure the degree to which lookahead contributes to resolving ambiguities encountered while reading.
L’Herbelot had asserted, that the most ancient Korans, written in the Cufic character, had no vowel points; and that these were first invented by Jahia–ben Jamer, who died in the 127th year of the Hegira. “Toderini’s History of Turkish Literature,” Analytical Review (1789)
Of COVID-19 Transmission Control
Authors: Oladejo Abiodun Omotayo , Jack Jackson T. C. B. 
Published: August 2022

Abstract
At the onset of the COVID-19 epidemic, world leaders introduced face masking and tactical urbanism aimed at reducing physical contacts. The goal of these measures, as argued by the proponents, is to curtail community transmission of the virus to enable herd immunity. The enforcement of these measures attracted contradictions related to human rights and citizen duty. In the Global North, the rising cases of COVID-19 have been linked to resistance to regulations aimed at containing the virus. Predominantly, the younger generation perceive these measures as infringements on their freedoms and rights. Conversely, in the Global South, the implementation of COVID-19 measures has been marred by instances of human rights violations and extra-judicial killings in extreme cases. There are reported cases of arbitrary arrests, battery, and extortions consequent upon the enforcement of physical distancing and use of face masks. The paradox of the differential experiences between the Global North and South informed this article. Relying on extant literature and Procedural Justice Theory, the authors submit that rights and duties are not mutually exclusive, but can be blended through a proactive participatory process within a democratic framework. The article recommends a multi-level legislative framework for disaster management.
Justice in International Negotiation Training
Authors: Meerts Paul 
Published: August 2022

Abstract
The notion of justice is a vital element in international negotiation training especially if the participants are from the political and diplomatic realms. This is the case not only because trainees need to be aware of existing judicial organizations, but foremost, because of the role that fairness plays in helping negotiation processes develop and conclude agreements that are then implemented successfully. Unfair outcomes are normally ineffective. This article highlights the role of justice in a training environment of growing complexity. It deals with simple bilateral exercises, as well as negotiations that involve constituencies and mediators, multiparty bargaining situations, and complex multilateral diplomatic conferences. Justice in the training environment touches upon issues like positions and interests, power and influence, strategy and tactics, skills and styles, culture and emotions, and above all, on actors and processes in the context of politics, diplomacy and history.
Negotiating in China: Principles of Justice
Authors: Faure Guy Olivier 
Published: August 2022

Abstract
China does not have a unified and consistent ethical understanding. Ethics have to be mostly conceived and applied in personal terms. At the negotiation table, parties bring their own moral principles and values from their cultural background, education, and experience. Justice principles anchored in Chinese moral philosophy clearly take precedence over legal justice principles. For a Chinese negotiator, striking a deal is a process of balancing between two contradictory sets of values: Confucius’ notions of rightness, and those of modern distributive (and procedural) justice. Now, distributive justice implies a whole range of criteria, such as rewards according to efforts, merits, and contribution, as well as need. Equality is still not on the Chinese justice agenda. Fairness has to find its own way between guanxi requirements, traditional nepotism, the influence of symbols, propitious numbers, references to ancestors, feng shui, and astrology.
Negotiating Aspirations in Displacement
Authors: Willmann-Robleda Zubia 
Published: August 2022

Abstract
This article explores women’s aspirations during different stages of seeking asylum and settling in Norway and how their aspirations were influenced by each stage’s characteristics and circumstances. Two ethnographic fieldwork phases involved following nine women during approximately one and a half years through the asylum process and the early stages of settlement in Norway (2017–2019). The data show that while living in an asylum centre, the women’s narratives about their aspirations were permeated primarily by their uncertain circumstances. After settling in the municipalities, they began to encounter multiple limitations to their aspirations, which led them to become demotivated and eventually readjust their aspirations. This article shows the effects that the experience of being an asylum seeker and that of resettling in a new country has on people’s aspirations and motivation, something which can in turn have an influence on how they decide to incorporate into the new society.
Duty of Care: Consular Diplomacy Response of Baltic and Nordic Countries to COVID-19
Authors: Birka Ieva , Kļaviņš Didzis , Kits Roberts 
Published: August 2022

Summary
Declaring the COVID-19 pandemic in early 2020 left thousands of travellers stranded, propelling consular work to the forefront, and testing governments’ capacity to aid their nationals abroad. While all consular departments provided assistance and duty of care (DoC) through information and guidance, some were reactive while others were proactive, and some were willing to make exceptions and engage in pastoral care. Analysis of the Baltic and Nordic countries’ reactions to the initial outbreak of COVID-19 shows us how DoC diverged in practice, and to note the transition of consular affairs into consular diplomacy and its interplay with facets of digital, citizen-centric and diaspora diplomacy. The conclusion is that all eight countries exceeded normal consular practice and exhibited some level of pastoral DoC, with Latvia and Lithuania exhibiting high levels of pastoral care. In parallel, Lithuania and Denmark, in their responses, effectively incorporated innovative elements of digital and diaspora diplomacy.