bluuebunny/crossref_metadata_2025_split huggingface dataset:
Usability, Feasibility, and Effect of a Biocueing Intervention in Addition to a Moderated Digital Social Therapy-Platform in Young People With Emerging Mental Health Problems: A Mixed-Method Approach
Authors: van Doorn Marilon , Nijhuis Laurens A. , Monsanto Anne , van Amelsvoort Thérèse , Popma Arne , Jaspers Monique W. M. , Noordzij Matthijs L. , Öry Ferko G. , Alvarez-Jimenez Mario , Nieman Dorien H. 
Published: May 2022

IntroductionTo optimize treatment, it is of utmost importance to take into account the myriad of biological, social, and psychological changes that young people go through during adolescence which make them more vulnerable for developing mental health problems. Biocueing, a non-invasive method to transform physiological parameters into an observable signal, could strengthen stress- and emotion regulation by cueing physiologically unusual values in daily life. The aim of this study is to investigate the usability, feasibility, and exploratory effect of biocueing in addition to ENgage YOung people earlY (ENYOY), a moderated digital social therapy-platform, in young people with emerging mental health complaints.MethodsA user-centered mixed-method design was used. A focus group was conducted to optimize the ENYOY-platform and biocueing intervention. Biocueing was operationalized by a smartwatch and the Sense-IT app. A within-subjects design was used; 10 days for all participants ‘biofeedback off' (control), followed by 10 days ‘biofeedback on' (experimental). Emotional awareness and perceived stress were measured using ecological momentary assessment. Eight individuals participated. User-friendliness, usability, and acceptance were assessed using a qualitative design.ResultsFindings from the focus group resulted in several adaptations of the biocueing intervention to the ENYOY-platform and vice versa. The average measurement compliance rate was 78.8%. Level-one findings showed different individual effects on perceived stress and emotional awareness. Level-two analyses showed no overall effects on perceived stress (B = −0.020, p = 0.562) and overall positive effects on emotional awareness (B = 0.030, p = 0.048) with small effect sizes (Improvement Rate Difference = 0.05–0.35). The intervention was found to be acceptable and showed moderate usability. Participants indicated they experienced improvements in reflection on feelings and changes in behavior, such as pausing and evaluating the situation.ConclusionThese preliminary results show that biocueing could be a promising addition to digital treatment platforms and help young people become more emotionally aware. Improvements should be made regarding the usability and acceptability of the smartwatch, as well as more extensive integration of the biocueing intervention with a digital treatment platform. It would be relevant to gain a better understanding of which individuals would benefit most from an additional biocueing intervention.
Protocol for Comparing the Efficacy of Three Reconstruction Methods of the Digestive Tract (Kamikawa Versus Double-Tract Reconstruction Versus Tube-Like Stomach) After Proximal Gastrectomy
Authors: Wang Wei Dong , Gao Rui Qi , Chen Tong , Dong Dan Hong , Yang Qin Chuan , Zhou Hai Kun , Wei Jiang Peng , Yu Peng Fei , Yang Xi Sheng , Li Xiao Hua , Ji Gang 
Published: May 2022

BackgroundAppropriate gastrointestinal reconstruction after proximal gastrectomy can effectively reduce the incidence of postoperative complications in patients with proximal early gastric cancer. However, there is still great controversy about the choice of digestive tract reconstruction after proximal gastrectomy, and there is no clinical consensus on the choice of digestive tract reconstruction after proximal gastrectomy. Currently, there is a lack of large-sample, prospective, randomized controlled studies to compare the efficacy of Kamikawa, double-tract reconstruction, and tube-like stomach reconstruction after proximal gastrectomy.Methods/designThis study will investigate the efficacy of three reconstruction methods after proximal gastrectomy in a prospective, multicenter, randomized controlled trial, which will enroll 180 patients with proximal early gastric cancer. Patients will be randomly divided into three groups: Group A (Kamikawa, n = 60), Group B (double-tract reconstruction, n = 60), and Group C (tube-like stomach, n = 60). The general information, past medical history, laboratory findings, imaging findings, and surgical procedures of the patients will be recorded and analyzed. The incidence of reflux esophagitis will be recorded as the primary endpoint. The incidence of anastomotic leakage, anastomotic stenosis, operative time and intraoperative blood loss will be recorded as secondary endpoints.DiscussionThis study will establish a large-sample, prospective, randomized controlled trial to compare the efficacy of Kamikawa, double-tract reconstruction, and tube-like stomach reconstruction after proximal gastrectomy.Trial registrationThis study was approved by the Chinese Clinical Trial Registry and registered on April 30, 2021. The registration number is ChiCTR2100045975.
A comparative Study of Novel Extramedullary Fixation and Dynamic Hip Screw in the Fixation of Intertrochanteric Fracture: A Finite-Element Analysis
Authors: Ding Kai , Zhu Yanbin , Wang Haicheng , Li Yonglong , Yang Weijie , Cheng Xiaodong , Zhang Yingze , Chen Wei , Zhang Qi 
Published: May 2022

BackgroundDynamic hip screw (DHS) is one of the most widely internal fixations for stabilizing intertrochanteric fracture, however, with a high risk of postoperative complications. The triangle support fixation plate (TSFP) is developed to reduce the postoperative complications. The purpose of study is to evaluate the biomechanical performance of the DHS and TSFP and demonstrate the rationality of triangular internal fixation for stabilizing intertrochanteric fractures.MethodsThe CT data of the proximal femur were used to establish finite-element models. Evans type I and IV intertrochanteric fracture were constructed and stabilized with the DHS and TSFP. The Von-Mises stress, maximum principal stress, minimum principal stress, and displacement were used to evaluate the biomechanical effect of two implants on intertrochanteric fracture.ResultsUnder a 600N axial load, the maximum stress and displacement of an intact proximal femur were 13.78 MPa and 1.33 mm, respectively. The peak stresses of the bone in the TSFP were 35.41 MPa and 68.97 MPa for treating Evans type I and IV intertrochanteric fractures, respectively, which were lower than those in the DHS. The maximum overall displacement and relative distance of the fracture surface in the DHS fixation model were 1.66 mm and 0.10 mm for treating Evans type I intertrochanteric fracture, which was 29.59% and 150% higher than that in the TSFP, and were 2.24 mm and 0.75 mm for treating Evans type IV intertrochanteric fracture, which was 42.58% and 650% higher than that in the TSFP.ConclusionsIn conclusion, the TSFP has obvious advantages in stress distribution and stability than the DHS, providing a promising option for the treatment of intertrochanteric fractures.
Contralateral vs. Ipsilateral Approach to Superior Hypophyseal Artery Aneurysms: An Anatomical Study and Morphometric Analysis
Authors: Sahin Balkan , Aydin Serdar Onur , Yilmaz Mehmet Ozgur , Saygi Tahsin , Hanalioglu Sahin , Akyoldas Goktug , Baran Oguz , Kiris Talat 
Published: May 2022

IntroductionSurgical clipping of superior hypophyseal artery (SHA) aneurysms is a challenging task for neurosurgeons due to their close anatomical relationships. The development of endovascular techniques and the difficulty in surgery have led to a decrease in the number of surgical procedures and thus the experience of neurosurgeons in this region. In this study, we aimed to reveal the microsurgical anatomy of the ipsilateral and contralateral approaches to SHA aneurysms and define their limitations via morphometric analyses of radiological anatomy, three-dimensional (3D) modeling, and surgical illustrations.MethodFive fixed and injected cadaver heads underwent dissections. In order to make morphometric measurements, 75 cranial MRI scans were reviewed. Cranial scans were rendered with a module and used to produce 3D models of different anatomical structures. In addition, a medical illustration was drawn that shows different sizes of aneurysms and surgical clipping approaches.ResultsFor the contralateral approach, pterional craniotomy and sylvian dissection were performed. The contralateral SHA was reached from the prechiasmatic area. The dissected SHA was approached with an aneurysm clip, and maneuverability was evaluated. For the ipsilateral approach, pterional craniotomy and sylvian dissection were performed. The ipsilateral SHA was reached by mobilizing the left optic nerve with left optic nerve unroofing and left anterior clinoidectomy. MRI measurements showed that the area of the prechiasm was 90.4 ± 36.6 mm2 (prefixed: 46.9 ± 10.4 mm2, normofixed: 84.8 ± 15.7 mm2, postfixed: 137.2 ± 19.5 mm2, p &lt; 0.001), the distance between the anterior aspect of the optic chiasm and the limbus sphenoidale was 10.0 ± 3.5 mm (prefixed: 5.7 ± 0.8 mm, normofixed: 9.6 ± 1.6 mm, postfixed:14.4 ± 1.6 mm, p &lt; 0.001), and optic nerves’ interneural angle was 65.2° ± 10.0° (prefixed: 77.1° ± 7.3, normofixed: 63.6° ± 7.7°, postfixed: 57.7° ± 5.7°, p: 0.010).ConclusionAnatomic dissections along with 3D virtual model simulations and illustrations demonstrated that the contralateral approach would potentially allow for proximal control and neck control/clipping in smaller SHA aneurysm with relatively minimal retraction of the contralateral optic nerve in the setting of pre- or normofixed chiasm, and ipsilateral approach requires anterior clinodectomy and optic unroofing with considerable optic nerve mobilization to control proximal ICA and clip the aneurysm neck effectively.
Risk Factors of Postoperative Meningitis in Lateral Ventricular Trigone Meningiomas: A Clinical Analysis of 64 Patients
Authors: Han Xiaodi , Hu Tianhao , Wang Run , Li Longjie , Yu Juanhan , Zhang Li , Han Sheng 
Published: May 2022

PurposePatients with intraventricular tumors are more susceptible to postoperative meningitis (POM) than other intracranial tumors. In this study, we explored the risk factors of POM in lateral ventricular trigone meningiomas (LVTMs).MethodsClinical features of 64 patients with LVTMs were analyzed. Age, gender, body mass index, medical history, intraoperative blood loss (IBL), intraventricular drainage placement, surgical duration, tumor grade, postoperative tumor cavity hemorrhage, and tumor size were included in univariate and multivariate analyses of POM.ResultsOf the 64 patients, 14 patients (21.9%) received diagnosis of POM. The univariate analysis revealed IBL ≥400 mL (odds ratio [OR], 9.012; p = 0.003), tumor size ≥50 cm3 (OR, 3.071; p = 0.080), and surgical duration ≥5 h (OR, 2.970; p = 0.085) were considered possible risk factors for POM (p &lt; 0.10). Tumor size (R = 0.514) and surgical duration (R = 0.624) were significantly correlated with IBL (p &lt; 0.05). In the multivariate analysis, only IBL was found to be an independent risk factor for POM.ConclusionThe IBL ≥400 mL is independently associated with the increased risk of POM in LVTM patients. Our results demonstrate the importance of controlling IBL for preventing POM, especially in large tumors and long surgeries.
Influence of pH, Humic Acids, and Salts on the Dissipation of Amoxicillin and Azithromycin Under Simulated Sunlight
Authors: Rodríguez-López Lucía , Santás-Miguel Vanesa , Núñez-Delgado Avelino , Álvarez-Rodríguez Esperanza , Pérez-Rodríguez Paula , Arias-Estévez Manuel 
Published: May 2022

This work is focused on the study of the dissipation of the antibiotics amoxicillin (AMX) (an amino penicillin) and azithromycin (AZT) (belonging to the macrolide group), performed at a laboratory scale, under simulated sunlight and in the dark, at pH values 4.0, 5.5, and 7.2, and in the presence of humic acids and different inorganic salts. The results indicate that AMX is more affected than AZT by simulated sunlight, with half-lives ranging 7.7–9.9 h for AMX and 250–456 h for AZT. The lowest half-life values were obtained at pH 7.2 for AMX (7.7 h) and at pH 4.0 for AZT (250 h). Regarding the effect of various salts, the presence of NaNO3 causes that C/C0 decreases from 0.6 to 0 under simulated sunlight, having no effect on the dissipation of AMX in the dark. However, in the presence of FeCl3 at concentrations of 500 mg L−1, AMX suffered total dissipation, both under simulated sunlight and in the dark. For AZT the influence was lower, and the salts that caused a higher increase in its dissipation were NaCl (with C/C0 decreasing from 0.5 to 0.2) and CaCl2 (C/C0 decreasing from 0.5 to 0.3). The presence of humic acids caused a slight increase in the dissipation of AMX, both under simulated sunlight and in the dark, a fact that was attributed to the adsorption of the antibiotic onto these organic substances, which, however, caused a more marked increase in the dissipation of AZT (reaching 68%) under simulated sunlight. The overall results of this research can be considered clearly relevant, mainly to determine the fate of AMX and AZT when these antibiotics reach the environment as pollutants, either as regards their exposure to natural sunlight, or in relation to the use of inactivation/photo-degradation systems in decontamination procedures focused on environmental compartments.
Faut-il légaliser le cannabis en France ? Un bilan socio-économique
Authors: Ben Lakhdar Christian , Kopp Pierre 
Published: May 2022

Should Cannabis be Legalized in France ? A Welfare Analysis.
This article compares the current legal regime of cannabis in France, based on the Prohibition Lawof 31 December 1970, with different legalization scenarios. Despite the difficulties inherent in observing an underground market, a welfare function is estimated under different legal regime scenarios. Decriminalization of consumption would increase welfare. Full liberalization of the cannabis market would generate a higher positive variation in welfare, while resolving the issue of prohibition. The economic benefit of full legalization of cannabis could be attributable not only to the creation of tax revenue but also to the saving of public resources currently allocated to repression.
Associations of Anxiety during the COVID-19 Pandemic with Patient Characteristics and Behaviors in CKD Patients: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study
Authors: Dorans Kirsten S. , Wright Nunes Julie A. , Schaubel Douglas E. , Sha Daohang , Schrauben Sarah J. , Nelson Robert G. , Rao Panduranga S. , Cohen Debbie L. , Appel Lawrence J. , Lash James P. , Rahman Mahboob , Feldman Harold I. 
Published: May 2022

Key Points

Several factors were associated with higher coronavirus disease 2019 (COVID-19)-related anxiety.Higher COVID-19-related anxiety was associated not only with mask wearing but also with weight gain and less adherence to healthier lifestyles.Interventions are needed to support healthy behaviors in patients with CKD experiencing increased anxiety during the COVID-19 pandemic.

Background
Chronic kidney disease (CKD) is associated with anxiety and depression. Although the coronavirus disease 2019 (COVID-19) pandemic has increased stressors on patients with CKD, assessments of anxiety and its predictors and consequences on behaviors, specifically virus mitigation behaviors, are lacking.

Methods
From June to October 2020, we administered a survey to 1873 patients in the Chronic Renal Insufficiency Cohort (CRIC) Study, asking participants about anxiety related to the COVID-19 pandemic. We examined associations between anxiety and participant demographics, clinical indexes, and health literacy and whether anxiety was associated with health-related behaviors and COVID-19 mitigation behaviors.

Results
The mean age of the study population was 70 years (SD=9.6 years), 47% were women, 39% were Black non-Hispanic, 14% were Hispanic, and 38% had a history of cardiovascular disease. In adjusted analyses, younger age, being a woman, Hispanic ethnicity, cardiovascular disease, household income <$20,000, and marginal or inadequate health literacy predicted higher anxiety. Higher global COVID-19-related anxiety scores were associated with higher odds of reporting always wearing a mask in public (OR=1.3 [95% CI, 1.14 to 1.48], P<0.001) and of eating less healthy foods (OR=1.29 [95% CI, 1.13 to 1.46], P<0.001), reduced physical activity (OR=1.32 [95% CI, 1.2 to 1.45], P<0.001), and weight gain (OR=1.23 [95% CI, 1.11 to 1.38], P=0.001).

Conclusions
Higher anxiety levels related to the COVID-19 pandemic were associated not only with higher self-reported adherence to mask wearing but also with higher weight gain and less adherence to healthy lifestyle behaviors. Interventions are needed to support continuation of healthy lifestyle behaviors in patients with CKD experiencing increased anxiety related to the pandemic.
Oligomer absorption and calculation of the maximum content of dispersed particles in dispersed fi lled polymer composites
Authors: KHARLAMOVA K. I. , DERGUNOVA E. R. , SIMONOV-EMELYANOV I. D. 
Published: May 2022

The paper presents a method for determining the maximum content of dispersed filler (φm) in dispersed-filled polymer composite materials (DFPCM) by oligomer-absorption.For the first time, data on the values of the parameter φm in the DNPCM obtained from oligomer- (Y, g/100 g) and oil absorption method (X, g/100 g) are presented.The dependences of the parameter φm on the particles size for fillers with a particle size from 50nm to 250 microns are presented.It is shown, that the main advantage of using the new method for determining the parameter φm is the possibility to bring the dispersed system closer to the real conditions for DFPCM production and thus, to increase the reliability of the results.
Perbedaan Respon Stres Antara Pasien Stemi Dengan Nonstemi Selama Masa Perawatan Dirumah Sakit
Authors: Rajagukguk Tati Lasmarito , Damanik Chrisyen , Rusdi Rusdi 
Published: May 2022

Latar Belakang: : Sindrom Koroner Akut merupakan penyebab utama terjadinya kematian mendadak pada seseorang, stres psikologis yang dihasilkan mempengaruhi kesehatan jantung dan pemulihan. Tujuan: Untuk mengetahui perbedaan respon stres antara pasien Stemi dengan Non stemi Selama Masa Perawatan di Rumah Sakit. Metode: Jenis penelitian ini adalah penelitian kuantitatif, dengan pendekatan crossectional, dengan desain studi komparatif dilaksanakan diruang intensif di salah satu rumah sakit Kecamatan Tenggarong , Melibatkan 24 pasien dengan teknik Non Probability Sampling dengan jenis purposive sampling yang telah memenuhi kriteria inklusi, pengumpulan data menggunakan kuesioner PSS ( Perceived stress scale ) dengan uji hipotesis Independent T Test Hasil: Skor respon stres pada pasien stemi berada pada mean 28,42 dengan standar deviasi 3.34 dan nonstemi pada mean 25,08 dengan standar deviasi 1.37, dengan beda mean 3.33 sehingga pasien dalam kategori stres. Kesimpulan: Terdapat Perbedaan Respon Stres Antara Pasien Stemi dengan Nonstemi Selama Masa Perawatan di Rumah SakitRekomendasi: Diharapakan dapat digunakan sebagai acuan dalam studi eksperimen untuk meneliti bagaimana cara mengurangi respon stres berat pada pasien stemi dengan nonstemi selama masa perawatan dirumah sakit.
Linear response theory-based theoretical approach to structural changes in a polymer induced by β-decay of substituted tritium
Authors: Kawanami Ryuta , Fujiwara Susumu , Nakamura Hiroaki , Omata Kazumi 
Published: May 2022

Abstract
Polymers exposed to tritiated water undergo hydrogen defects caused by isotope substitution and subsequent β-decay of substituted tritium, causing structural changes and loss of function in the biopolymers. Here, based on linear response theory, we predict the structural change of tritium-damaged polyethylene using the equilibrium trajectory of undamaged polyethylene to reduce the computation time of molecular dynamics simulations. Specifically, the ensemble average of the change in a physical quantity, such that it represents a structural change before and after damage, was calculated numerically using the time derivative of the total potential energy difference derived analytically and the physical quantity obtained from the simulation of undamaged polyethylene on the basis of linear response theory. A comparison between theoretical and simulation results revealed that the characteristic oscillation behaviors of the structural response of polyethylene can be predicted, whereas the quantitative prediction of the steady-state values over a long period is difficult.
Theory of Doubly-Shielded Coupled Lines for Directional Couplers of Various Directivity Types with Impedance Transformation
Authors: Sychev Aleksandr , Bondar Vladislav , Dagba Kezhik , Stepanyuga Anton , Rudyi Nickolai 
Published: May 2022

<p>Coupled lines with a double shielding in weakly and strongly inhomogeneous dielectric media are studied. They have specific properties that allow creation of impedance-transforming directional couplers with given directivity type. The proposed models and synthesis techniques takes into account both electric asymmetry and dielectric inhomogeneity. Numerical simulations and measurements prove the correctness of the general theory, and the possibility of creating co-, contra- and trans-directional couplers with impedance-transforming and phase-shifting properties. The results will be useful for finding new design solutions of advanced couplers and microwave circuits. </p>
PHYSICOCHEMICAL PROPERTIES AND BIOLOGICAL ACTIVITIES OF MANGO (MAGNIFERA INDICA L.) SEED KERNEL AND PEEL OILS
Authors: Yusuf Zekeria , Malede Alemtsehay , Desta Mulugeta , Idris Megersa , Seyida Sultan 
Published: May 2022

The peel and kernels mango (Mangifera indica L.) processing by products can be used as a source of valuable products. Therefore, the present study was attempted to study physicochemical properties, antioxidant and antimicrobial activities of mango seed kernel and peel wastes. The result of physicochemical properties indicated that significantly higher oil yield (38.75±1.77), specific gravity (0.86±0.04), acid value (2.66±0.20) and free fatty acid value (1.34±0.12); and higher DPPH (16.70±0.70) antioxidant activities were recorded for mango seed oil extract. However, significantly higher hydrogen peroxide scavenging activity (HPSA, 31.10±1.70) and ascorbic acid (43.00±2.73) were recorded for fruit peel oil extract. Stronger antibacterial activity with maximum zone of inhibition (16.50 mm), minimum inhibitory concentration MIC (0.10µl/ml) and corresponding minimum bactericidal concentration MBC (0.20 µl/ml) was recorded for seed oil extract against S. aureus. Stronger antifungal activity with maximum zone of inhibition (16.47 mm), MIC (0.05 µl/ml, the least value) and MFC (0.10 µl/ml) for seed oil extract against C. albicans. It can be concluded from the results of present study that seed oil extract was found to be more effective antioxidant and antimicrobial potential than peel oil extract in mango (M. indica L.)