bluuebunny/crossref_metadata_2025_split huggingface dataset:
Replicative manufacturing of metal moulds for low surface roughness polymer replication
Authors: Kluck Sebastian , Hambitzer Leonhard , Luitz Manuel , Mader Markus , Sanjaya Mario , Balster Andreas , Milich Marcel , Greiner Christian , Kotz-Helmer Frederik , Rapp Bastian E. 
Published: August 2022

AbstractTool based manufacturing processes like injection moulding allow fast and high-quality mass-market production, but for optical polymer components the production of the necessary tools is time-consuming and expensive. In this paper a process to fabricate metal-inserts for tool based manufacturing with smooth surfaces via a casting and replication process from fused silica templates is presented. Bronze, brass and cobalt-chromium could be successfully replicated from shaped fused silica replications achieving a surface roughnesses of Rq8 nm and microstructures in the range of 5 µm. Injection moulding was successfully performed, using a commercially available injection moulding system, with thousands of replicas generated from the same tool. In addition, three-dimensional bodies in metal could be realised with 3D-Printing of fused silica casting moulds. This work thus represents an approach to high-quality moulding tools via a scalable facile and cost-effective route surpassing the currently employed cost-, labour- and equipment-intensive machining techniques.
Glassy thermal conductivity in Cs3Bi2I6Cl3 single crystal
Authors: Acharyya Paribesh , Ghosh Tanmoy , Pal Koushik , Rana Kewal Singh , Dutta Moinak , Swain Diptikanta , Etter Martin , Soni Ajay , Waghmare Umesh V. , Biswas Kanishka 
Published: August 2022

AbstractAs the periodic atomic arrangement of a crystal is made to a disorder or glassy-amorphous system by destroying the long-range order, lattice thermal conductivity, κL, decreases, and its fundamental characteristics changes. The realization of ultralow and unusual glass-like κL in a crystalline material is challenging but crucial to many applications like thermoelectrics and thermal barrier coatings. Herein, we demonstrate an ultralow (~0.20 W/m·K at room temperature) and glass-like temperature dependence (2–400 K) of κL in a single crystal of layered halide perovskite, Cs3Bi2I6Cl3. Acoustic phonons with low cut-off frequency (20 cm−1) are responsible for the low sound velocity in Cs3Bi2I6Cl3 and make the structure elastically soft. While a strong anharmonicity originates from the low energy and localized rattling-like vibration of Cs atoms, synchrotron X-ray pair-distribution function evidence a local structural distortion in the Bi-halide octahedra and Cl vacancy. The hierarchical chemical bonding and soft vibrations from selective sublattice leading to low κL is intriguing from lattice dynamical perspective as well as have potential applications.
In-situ growth of robust superlubricated nano-skin on electrospun nanofibers for post-operative adhesion prevention
Authors: Wang Yi , Xu Yuanhang , Zhai Weijie , Zhang Zhinan , Liu Yuhong , Cheng Shujie , Zhang Hongyu 
Published: August 2022

AbstractIt is a great challenge to achieve robustly bonded, fully covered, and nanoscaled coating on the surface of electrospun nanofibers. Herein, we develop a controllable, facile, and versatile strategy to in-situ grow superlubricated nano-skin (SLNS) on the single electrospun nanofiber. Specifically, zwitterionic polymer chains are generated from the nanofiber subsurface in an inside-out way, which consequently form a robust network interpenetrating with the polymeric chains of the nanofiber matrix. The nanofibers with SLNS are superlubricated with the coefficient of friction (COF) lower than 0.025, which is about 16-fold of reduction than the original nanofibers. The time-COF plot is very stable after 12, 000 cycles of friction test, and no abrasion is observed. Additionally, the developed nanofibrous membranes possess favorable tensile property and biocompatibility. Furthermore, the nanofibrous membranes with SLNS achieve prevention of post-operative adhesion, which is confirmed in both rat tendon adhesion model and abdominal adhesion model. Compared with clinically-used antiadhesive membranes such as Interceed and DK-film, our nanofibrous membranes are not only more effective but also have the advantage of lower production cost. Therefore, this study demonstrates a potential of the superlubricated nanofibrous membranes in-situ grown based on a SLNS strategy for achieving prevention of post-operative adhesion in clinics.
Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER
Authors: Jhund Pardeep S. , Kondo Toru , Butt Jawad H. , Docherty Kieran F. , Claggett Brian L. , Desai Akshay S. , Vaduganathan Muthiah , Gasparyan Samvel B. , Bengtsson Olof , Lindholm Daniel , Petersson Magnus , Langkilde Anna Maria , de Boer Rudolf A. , DeMets David , Hernandez Adrian F. , Inzucchi Silvio E. , Kosiborod Mikhail N. , Køber Lars , Lam Carolyn S. P. , Martinez Felipe A. , Sabatine Marc S. , Shah Sanjiv J. , Solomon Scott D. , McMurray John J. V. 
Published: August 2022

AbstractWhether the sodium–glucose cotransporter 2 inhibitor dapagliflozin reduces the risk of a range of morbidity and mortality outcomes in patients with heart failure regardless of ejection fraction is unknown. A patient-level pooled meta-analysis of two trials testing dapagliflozin in participants with heart failure and different ranges of left ventricular ejection fraction (≤40% and >40%) was pre-specified to examine the effect of treatment on endpoints that neither trial, individually, was powered for and to test the consistency of the effect of dapagliflozin across the range of ejection fractions. The pre-specified endpoints were: death from cardiovascular causes; death from any cause; total hospital admissions for heart failure; and the composite of death from cardiovascular causes, myocardial infarction or stroke (major adverse cardiovascular events (MACEs)). A total of 11,007 participants with a mean ejection fraction of 44% (s.d. 14%) were included. Dapagliflozin reduced the risk of death from cardiovascular causes (hazard ratio (HR) 0.86, 95% confidence interval (CI) 0.76–0.97; P = 0.01), death from any cause (HR 0.90, 95% CI 0.82–0.99; P = 0.03), total hospital admissions for heart failure (rate ratio 0.71, 95% CI 0.65–0.78; P < 0.001) and MACEs (HR 0.90, 95% CI 0.81–1.00; P = 0.045). There was no evidence that the effect of dapagliflozin differed by ejection fraction. In a patient-level pooled meta-analysis covering the full range of ejection fractions in patients with heart failure, dapagliflozin reduced the risk of death from cardiovascular causes and hospital admissions for heart failure (PROSPERO: CRD42022346524).
Dasymetric population mapping based on US census data and 30-m gridded estimates of impervious surface
Authors: Swanwick Rachel H. , Read Quentin D. , Guinn Steven M. , Williamson Matthew A. , Hondula Kelly L. , Elmore Andrew J. 
Published: August 2022

AbstractAssessment of socio-environmental problems and the search for solutions often require intersecting geospatial data on environmental factors and human population densities. In the United States, Census data is the most common source for information on population. However, timely acquisition of such data at sufficient spatial resolution can be problematic, especially in cases where the analysis area spans urban-rural gradients. With this data release, we provide a 30-m resolution population estimate for the contiguous United States. The workflow dasymetrically distributes Census block level population estimates across all non-transportation impervious surfaces within each Census block. The methodology is updatable using the most recent Census data and remote sensing-based observations of impervious surface area. The dataset, known as the U.G.L.I (updatable gridded lightweight impervious) population dataset, compares favorably against other population data sources, and provides a useful balance between resolution and complexity.
ADTC-InSAR: a tropospheric correction database for Andean volcanoes
Authors: Lopez-Pozo Fernanda , Abarca-del-Rio Rodrigo , Lara Luis E. 
Published: August 2022

AbstractMonitoring geophysical hazards requires a near real-time response and precise interpretation of InSAR data, typically recording minute surface deformations. Accurate tropospheric adjustment is an essential aspect of InSAR processing. This study provides a free database of ready-to-use Tropospheric Correction for InSAR for the three volcanic zones from north to south of the Andes. Average Daily Tropospheric Correction for InSAR (ADTC-InSAR) is a collection of average daily tropospheric delay matrices created using ECMWF re-analysis of the global atmosphere and surface conditions (ERA5) as atmospheric data and TRAIN software. The construction method and annual variation according to the climatic zones are provided, and its effectiveness is evaluated. ADTC-InSAR facilitates the generation of tropospheric corrections in InSAR with easy access, fast application, and accuracy comparable to TRAIN. Its purpose is to serve as a starting point for tropospheric correction in the event of emergency response to extreme occurrences and as a reference for other research and academic objectives.
Global inventory of suitable, cultivable and available cropland under different scenarios and policies
Authors: Schneider Julia M. , Zabel Florian , Mauser Wolfram 
Published: August 2022

AbstractWhere land-use change and particularly the expansion of cropland could potentially take place in the future is a central research question to investigate emerging trade-offs between food security, climate protection and biodiversity conservation. We provide consistent global datasets of land potentially suitable, cultivable and available for agricultural use for historic and future time periods from 1980 until 2100 under RCP2.6 and RCP8.5, available at 30 arc-seconds spatial resolution and aggregated at country level. Based on the agricultural suitability of land for 23 globally important food, feed, fiber and bioenergy crops, and high resolution land cover data, our dataset indicates where cultivation is possible and how much land could potentially be used as cropland when biophysical constraints and different assumptions on land-use regulations are taken into account. By serving as an input for land-use models, the produced data could improve the comparability of the models and their output, and thereby contribute to a better understanding of potential land-use trade-offs.
Real-world behavioral dataset from two fully remote smartphone-based randomized clinical trials for depression
Authors: Pratap Abhishek , Homiar Ava , Waninger Luke , Herd Calvin , Suver Christine , Volponi Joshua , Anguera Joaquin A. , Areán Pat 
Published: August 2022

AbstractMost people with mental health disorders cannot receive timely and evidence-based care despite billions of dollars spent by healthcare systems. Researchers have been exploring using digital health technologies to measure behavior in real-world settings with mixed results. There is a need to create accessible and computable digital mental health datasets to advance inclusive and transparently validated research for creating robust real-world digital biomarkers of mental health. Here we share and describe one of the largest and most diverse real-world behavior datasets from over two thousand individuals across the US. The data were generated as part of the two NIMH-funded randomized clinical trials conducted to assess the effectiveness of delivering mental health care continuously remotely. The longitudinal dataset consists of self-assessment of mood, depression, anxiety, and passively gathered phone-based behavioral data streams in real-world settings. This dataset will provide a timely and long-term data resource to evaluate analytical approaches for developing digital behavioral markers and understand the effectiveness of mental health care delivered continuously and remotely.
Mass spectrometry data on specialized metabolome of medicinal plants used in East Asian traditional medicine
Authors: Kang Kyo Bin , Jeong Eunah , Son Seungju , Lee Eunjin , Lee Seungjin , Choi Seong Yeon , Kim Hyun Woo , Yang Heejung , Shim Sang Hee 
Published: August 2022

AbstractTraditional East Asian medicine not only serves as a potential source of drug discovery, but also plays an important role in the healthcare systems of Korea, China, and Japan. Tandem mass spectrometry (MS/MS)-based untargeted metabolomics is a key methodology for high-throughput analysis of the complex chemical compositions of medicinal plants used in traditional East Asian medicine. This Data Descriptor documents the deposition to a public repository of a re-analyzable raw LC-MS/MS dataset of 337 medicinal plants listed in the Korean Pharmacopeia, in addition to a reference spectral library of 223 phytochemicals isolated from medicinal plants. Enhanced by recently developed repository-level data analysis pipelines, this information can serve as a reference dataset for MS/MS-based untargeted metabolomic analysis of plant specialized metabolites.
On controlled Hamilton and Hamilton–Jacobi differential equations of higher-order
Authors: Treanţă Savin , Nonlaopon Kamsing , Khan Muhammad Bilal 
Published: August 2022

AbstractIn this paper, we investigate the nonlinear dynamics associated with controlled Lagrangians involving higher-order derivatives. More precisely, we establish the controlled higher-order Hamilton ordinary differential equations (ODEs) and Hamilton–Jacobi partial differential equation (PDE) for the considered class of Lagrangians governed by higher-order derivatives of the state variables. Moreover, we formulate and prove an invariance result with respect to the state variable. In addition, in order to validate the theoretical results and to highlight their effectiveness, some illustrative applications are presented.
Spheroid co-culture of BMSCs with osteocytes yields ring-shaped bone-like tissue that enhances alveolar bone regeneration
Authors: Zhou Ying-Hui , Guo Yue , Zhu Jia-Yu , Tang Chen-Yi , Zhao Ya-Qiong , Zhou Hou-De 
Published: August 2022

AbstractOral and maxillofacial bone defects severely impair appearance and function, and bioactive materials are urgently needed for bone regeneration. Here, we spheroid co-cultured green fluorescent protein (GFP)-labeled bone marrow stromal cells (BMSCs) and osteocyte-like MLO-Y4 cells in different ratios (3:1, 2:1, 1:1, 1:2, 1:3) or as monoculture. Bone-like tissue was formed in the 3:1, 2:1, and 1:1 co-cultures and MLO-Y4 monoculture. We found a continuous dense calcium phosphate structure and spherical calcium phosphate similar to mouse femur with the 3:1, 2:1, and 1:1 co-cultures, along with GFP-positive osteocyte-like cells encircled by an osteoid-like matrix similar to cortical bone. Flake-like calcium phosphate, which is more mature than spherical calcium phosphate, was found with the 3:1 and 2:1 co-cultures. Phosphorus and calcium signals were highest with 3:1 co-culture, and this bone-like tissue was ring-shaped. In a murine tooth extraction model, implantation of the ring-shaped bone-like tissue yielded more bone mass, osteoid and mineralized bone, and collagen versus no implantation. This tissue fabricated by spheroid co-culturing BMSCs with osteocytes yields an internal structure and mineral composition similar to mouse femur and could promote bone formation and maturation, accelerating regeneration. These findings open the way to new strategies in bone tissue engineering.
Identifiability of parameters in mathematical models of SARS-CoV-2 infections in humans
Authors: Ciupe Stanca M. , Tuncer Necibe 
Published: August 2022

AbstractDetermining accurate estimates for the characteristics of the severe acute respiratory syndrome coronavirus 2 in the upper and lower respiratory tracts, by fitting mathematical models to data, is made difficult by the lack of measurements early in the infection. To determine the sensitivity of the parameter estimates to the noise in the data, we developed a novel two-patch within-host mathematical model that considered the infection of both respiratory tracts and assumed that the viral load in the lower respiratory tract decays in a density dependent manner and investigated its ability to match population level data. We proposed several approaches that can improve practical identifiability of parameters, including an optimal experimental approach, and found that availability of viral data early in the infection is of essence for improving the accuracy of the estimates. Our findings can be useful for designing interventions.
Impact of intravenous dexmedetomidine on gastrointestinal function recovery after laparoscopic hysteromyomectomy: a randomized clinical trial
Authors: Wu Yu , Cai Zenghua , Liu Lishuang , Wang Jinbao , Li Yanli , Kang Yuling , An Ni 
Published: August 2022

AbstractPostoperative intestinal ileus is common after laparoscopic surgery, the incidence of those after hysterectomy was 9.2%. Anesthesia is one of the independent risk factors of postoperative ileus. Dexmedetomidine has been widely used in perioperative anesthesia and previous reports suggested that intraoperative dexmedetomidine may be associated with the improvement of gastrointestinal function recovery after abdominal surgery. We hypothesized that dexmedetomidine could improve gastrointestinal function recovery after laparoscopic hysteromyomectomy. Participants in elective laparoscopic hysteromyomectomy were enrolled with a single dose of 0.5 μg kg−1 dexmedetomidine or the same volume of placebo intravenously administered for 15 min, followed by continuous pumping of 0.2 μg kg−1 h−1 of corresponding drugs until 30 min before the end of surgery. The primary outcome was the time to first flatus. Secondary outcomes were the time to first oral feeding and the first defecation, the occurrence of flatulence, pain score and postoperative nausea and vomiting until 48 h after the surgery. Eventually, 106 participants (54 in dexmedetomidine group and 52 in placebo group) were included for final analysis. The time to first flatus (SD, 25.83 [4.18] vs 27.67 [3.77], P = 0.019), oral feeding time (SD, 27.29 [4.40] vs 28.92 [3.82], P = 0.044), the time to first defecation (SD, 59.82 [10.49] vs 63.89 [7.71], P = 0.025), abdominal distension (n%, 12 (22.2) vs 21 (40.4), P = 0.044), PONV at 24 h (n%, 10 (18.5) vs 19 (36.5), P = 0.037), NRS 6 h (3.15(0.68) vs 3.46 (0.87), P = 0.043) and NRS 12 h (3.43 (0.88) vs 3.85 (0.85), P = 0.014) of dexmedetomidine group were significantly shorter than those of the placebo group. Intraoperative dexmedetomidine reduced the time to first flatus, first oral feeding, and first defecation. These results suggested that this treatment may be a feasible strategy for improving postoperative gastrointestinal function recovery in patients undergoing laparoscopic hysteromyomectomy.
The influence of Strzelin Quarry Lakes on small reservoir retention resources in the regional catchments
Authors: Jawecki Bartosz 
Published: August 2022

AbstractThe paper presents the results of the analysis of the volume of water retained in Strzelin Quarry Lakes (SQLs). The volume of retained water was estimated by using the computational method, where the proposed reduction factors were determined with the use of DTM (digital terrain model). 2.6 hm3 of water was retained in seventeen Strzelin Quarry Lakes, of which 1.2 hm3 in the Ślęza River catchment (3 quarry lakes), and 1.4 hm3 in the Oława River catchment (14 quarry lakes). The obtained data of the volume of water retained in SQLs were compared to the balance of the water retention capacity of water reservoirs in the catchments of the Ślęza River (0.809 hm3), part of the WR08 Bystrzyca balance catchments (16.190 hm3) and in the catchments of the Oława River (2.782 hm3), part of the WR09 Nysa Kłodzka balance catchment (104.960 hm3). Inclusion the volume of water retained in Strzelin Quarry Lakes in the small scale water retention (reservoirs and ponds) balance would increase the volume of retained water by 156.0% in the Ślęza catchment (by 7.8% in the WR08 Bystrzyca balance catchment) and by 49.5% in the Oława catchment (by 1,3% in the WR09 Nysa Kłodzka balance catchment). Under favorable hydrogeological and geomorphological conditions water reclamation of the excavations may be one of the main aspects of increasing the retention capacity of the catchment, what is particularly important in areas characterized by low water resources.
Effect of oral zinc regimens on human hepatic copper content: a randomized intervention study
Authors: Munk Ditte Emilie , Lund Laursen Tea , Teicher Kirk Frederik , Vilstrup Hendrik , Ala Aftab , Gormsen Lars Christian , Ott Peter , Damgaard Sandahl Thomas 
Published: August 2022

AbstractZinc inhibits intestinal copper uptake, an effect utilized for treating Wilson’s disease (WD). We used copper-64 (64Cu) PET/CT to examine how much four weeks of treatment with different zinc regimens reduced the hepatic 64Cu content after oral 64Cu administration and test if alternative regimens were noninferior to the standard regimen of zinc acetate 50 mg × 3 daily. Forty healthy persons were randomized to four different zinc protocols. The WD standard treatment zinc acetate 50 mg × 3 reduced the hepatic 64Cu content from 26.9 ± 7.5% to 13.3 ± 5.6% of the administered 64Cu. Zinc gluconate 50 mg × 3 was noninferior (P = 0.02) (35.8 ± 9.0% to 17.4 ± 7.5%). Zinc acetate 150 mg × 1 (33.1 ± 9.9% to 17.4 ± 7.5%) and zinc gluconate 150 mg × 1 (28.1 ± 6.7% to 22.0 ± 6.7%) were less effective. These effects were intra- and inter-individually highly variable, and 14% had no effect of any zinc regimen, which may explain disparities in zinc treatment efficacy in WD patients.
Maize grain yield enhancement in modern hybrids associated with greater stalk lodging resistance at a high planting density: a case study in northeast China
Authors: Cui Jingjing , Cui Zhengguo , Lu Yang , Lv Xiaofei , Cao Qingjun , Hou Yunlong , Yang Xiangyu , Gu Yan 
Published: August 2022

AbstractLodging resistance is a critical trait in modern maize breeding. This study aimed to examine maize stalk lodging and its related characteristics in response to increasing planting densities in modern hybrids. A two-year field trial was conducted from 2018 to 2019 with two widely grown commercial hybrids (‘Xy335’ and ‘Fm985’) and three planting density treatments of 4.5 × 104 (low density, LD), 6.5 × 104 (medium density, MD), and 8.5 × 104 plants/ha (high density, HD). New hybrid Fm985 had a significantly higher grain yield and lower lodging rate at HD, while there was no significance at LD and MD. Compared to Fm985, old hybrid Xy335 had a significantly high plant height, ear and gravity height, and culm length (CL) across the three planting densities, while opposite stalk bending strength (SBS), dry weight per unit length (DWPU), cross-sectional area, and the cellulose and lignin content in the basal internode were low. Correlation and path analysis revealed that kernel number per ear and lodging rate directly contributed to maize grain yield, while lodging-related traits of SBS, stem lignin, and DWPU had an indirect effect on maize grain yield, suggesting that modern hybrid maize yield enhancement is associated with greater stalk lodging resistance at a high planting density in northeast China.