bluuebunny/crossref_metadata_2025_split huggingface dataset:
Testing the Efficacy of Attitudinal Inoculation Videos to Enhance COVID-19 Vaccine Acceptance: Quasi-Experimental Intervention Trial
Authors: Piltch-Loeb Rachael , Su Max , Hughes Brian , Testa Marcia , Goldberg Beth , Braddock Kurt , Miller-Idriss Cynthia , Maturo Vanessa , Savoia Elena 
Published: April 2022

Background
Over the course of the COVID-19 pandemic, a variety of COVID-19-related misinformation has spread and been amplified online. The spread of misinformation can influence COVID-19 beliefs and protective actions, including vaccine hesitancy. Belief in vaccine misinformation is associated with lower vaccination rates and higher vaccine resistance. Attitudinal inoculation is a preventative approach to combating misinformation and disinformation, which leverages the power of narrative, rhetoric, values, and emotion.

Objective
This study seeks to test inoculation messages in the form of short video messages to promote resistance against persuasion by COVID-19 vaccine misinformation.

Methods
We designed a series of 30-second inoculation videos and conducted a quasi-experimental study to test the use of attitudinal inoculation in a population of individuals who were unvaccinated (N=1991). The 3 intervention videos were distinguished by their script design, with intervention video 1 focusing on narrative/rhetorical (“Narrative”) presentation of information, intervention video 2 focusing on delivering a fact-based information (“Fact”), and intervention video 3 using a hybrid design (“Hybrid”). Analysis of covariance (ANCOVA) models were used to compare the main effect of the intervention on the 3 outcome variables: ability to recognize misinformation tactics (“Recognize”), willingness to share misinformation (“Share”), and willingness to take the COVID-19 vaccine (“Willingness”).

Results
There were significant effects across all 3 outcome variables comparing inoculation intervention groups to controls. For the Recognize outcome, the ability to recognize rhetorical strategies, there was a significant intervention group effect (P<.001). For the Share outcome, support for sharing the mis- and disinformation, the intervention group main effect was statistically significant (P=.02). For the Willingness outcome, there was a significant intervention group effect; intervention groups were more willing to get the COVID-19 vaccine compared to controls (P=.01).

Conclusions
Across all intervention groups, inoculated individuals showed greater resistance to misinformation than their noninoculated counterparts. Relative to those who were not inoculated, inoculated participants showed significantly greater ability to recognize and identify rhetorical strategies used in misinformation, were less likely to share false information, and had greater willingness to get the COVID-19 vaccine. Attitudinal inoculation delivered through short video messages should be tested in public health messaging campaigns to counter mis- and disinformation.
KEBIASAAN MAKANAN DAN REPRODUKSI IKAN LUNDU (Macrones gulio) DI PERAIRAN MAJAKERTA, INDRAMAYU, JAWA BARAT, INDONESIA
Authors: Sulistiono Sulistiono , A. M. Simanjuntak Johansen 
Published: April 2022

Ikan lundu (Macrones gulio) merupakan salah satu ikan ekonomis penting dan banyak dimanfaatkan oleh masyarakat sebagai bahan pangan. Kajian mengenai aspek makanan dan reproduksi ikan lundu sebagai dasar dalam pengelolaan ikan tersebut masih sangat minim. Tujuan penelitian ini adalah mengkaji aspek kebiasaan makanan dan reproduksi ikan lundu yang mencakup jenis makanan, kelimpahan makanan, rasio kelamin, tingkat kematangan gonad, ukuran ikan pertama kali matang gonad, indeks kematangan gonad, fekunditas, dan diameter telur. Penelitian dilakukan selama tiga bulan, pada Bulan Desember 2014 - Februari 2015. Total ikan contoh yang diamati (n= 201 ekor ikan), terdiri dari 98 ekor ikan jantan dan 103 ekor ikan betina. Hasil penelitian menunjukkan bahwa ikan lundu termasuk ikan omnivora yang cenderung karnivora, dengan makanan utama berupa krustasea. Rasio kelamin ikan jantan dan ikan betina 1:1,1. Ikan betina lebih dahulu matang gonad dari pada ikan jantan. Fekunditas ikan lundu adalah 3100-24459 butir telur dengan modus penyebaran dua puncak yang mengindikasikan tipe pemijahan secara partial.
Plastic Surgery Considerations for the General Surgeon
Authors: Agnew Sonya P , Dumanian Gregory A. 
Published: April 2022

Plastic surgery does not claim a specific region of the body, a tissue type, a disease process, or a technique. Instead, plastic surgery holds central to its core the concepts of tissue perfusion and tissue rearrangement to restore function and appearance. Rather than being at the fringes of medicine and surgery, mastery of these issues allows the plastic surgeon to become a generalist and consultant to all of the surgical disciplines. Reconstructive surgery, wound healing, tissue perfusion, and vascularity are the general themes first discussed by the authors. Plastic surgery considerations for surgery of the abdomen, the breast, and the soft tissues are then covered in order, with all relevant procedures described. The authors discuss scar revisions and the principles of wound closure that favorably impact the final appearance in their conclusion.
This review contains 5 figures, 9 tables and 15 references
Keywords: Plastic surgery, reconstructive surgery, tissue perfusion, wound healing, panniculectomy, mammaplasty, omental flap, scar revision
GLP-2 Regulation of Dietary Fat Absorption and Intestinal Chylomicron Production via Neuronal Nitric Oxide Synthase (nNOS) Signaling
Authors: Grande Elisabeth M. , Raka Fitore , Hoffman Simon , Adeli Khosrow 
Published: April 2022

<p>Postprandial dyslipidemia is a metabolic condition commonly associated with insulin-resistant states, such as obesity and type 2 diabetes (T2D). It is characterized by the overproduction of intestinal chylomicron particles and excess atherogenic chylomicron remnants in circulation. We have previously shown that glucagon-like peptide-2 (GLP-2) augments dietary fat uptake and chylomicron production in insulin-resistant states; however, the underlying mechanisms remain unclear. Previous studies have implicated nitric oxide (NO) in the absorptive actions of GLP-2. Here, we report a novel role for neuronal NO synthase (nNOS)-mediated NO generation in lipid uptake and chylomicron formation based on studies in C57BL/6J mice, nNOS-/- mice, and Syrian golden hamsters, after intraduodenal and oral fat administration. GLP-2 treatment in WT mice significantly increased postprandial lipid accumulation and circulating apolipoprotein B48 protein levels, while these effects were abolished in nNOS-/- mice. nNOS inhibition in Syrian golden hamsters and PKG inhibition in WT mice also abrogated the effect of GLP-2 on postprandial lipid accumulation. These studies demonstrate a novel mechanism in which nNOS-generated NO is crucial for GLP-2-mediated lipid absorption and chylomicron production in both mouse and hamster models. Overall, our data implicates an nNOS-PKG mediated pathway in GLP-2-mediated stimulation of dietary fat absorption and intestinal chylomicron production. </p>
Energy security as an integral element of ensuring the economic security of the state in the national security strategies of Ukraine
Authors: Shevchenko O. 
Published: April 2022

The article reveals the evolution of energy security in Ukraine's national security strategies during the years of independence. It is determined that a number of issues related to the creation of the most effective system of energy security of the state support within the existing National Security Strategies of Ukraine at various stages of state formation remain unresolved, both at the legislative level and in the functioning of relevant competent state bodies.
The content of ensuring the energy security of the state in the four national security strategies of Ukraine is revealed. It is determined that the issue of ensuring energy security of the state requires a clear definition of the state in strategic priorities and goals that should correspond to current trends in the national economy and world realities in this area.
It was emphasized that in accordance with the Final Provisions of the National Security Strategy 2020 on the development of planning documents in the field of national security and defense, which will determine the ways and tools of its implementation, the Cabinet of Ministers of Ukraine on August 4, 2021 approved the Energy Security Strategy. Ukraine, which defines the target model of the energy security system as a component of national security.
It is emphasized that the Energy Security Strategy of Ukraine identifies 29 key threats to energy security. These include, in particular, external risks - cyber threats to critical energy infrastructure, aggression by the Russian Federation, and internal - possible failure to integrate with EU electricity and gas supply systems, depreciation of fixed assets, lack of energy reserves and more.
It is noted that the strategic approach is extremely important for such a complex sector of the economy as energy. Given the unstable situation in the geopolitical sphere, given the limited energy resources and the need to develop ecologically and with concern for the environment, we need to understand all the potential risks and threats that may affect the Ukrainian energy sector. That is why the Energy Security Strategy of Ukraine is necessary to ensure predictability of development and sustainability of the energy system, timely identification of threats and prevention.
Threats to national security in the field of energy security have been studied. It is emphasized that currently the most correct and meaningful definition of energy security is the definition, which is enshrined in the newly approved Energy Security Strategy of Ukraine. Thus, energy security is the protection of national interests in ensuring access to reliable, sustainable, affordable and modern energy sources in a technically reliable, safe, cost-effective and environmentally friendly way under normal conditions and in conditions of special or emergency conditions.
The directions of increase of efficiency of maintenance of energy security of Ukraine are defined.
STRATEGI PUSKESMAS TABANAN I DALAM PELAKSANAAN POSYANDU BALITA SEBAGAI UPAYA PEMANTAUAN STATUS GIZI BALITA PADA MASA PANDEMI COVID-19
Authors: Dewi I Dewa Ayu Bintang Pradnya , Kurniati Desak Putu Yuli 
Published: April 2022

Toddlers are vulnerable groups infected with COVID-19. Monitoring the nutritional status of toddlers through Posyandu Balita is very important to ensure the growth and development of toddlers is not disturbed. During the COVID-19 pandemic, monitoring the nutritional status of toddlers did not run optimally. This study aims to find out the strategy of Puskesmas Tabanan I in the implementation of Posyandu Balita as an effort to monitor the nutritional status of toddlers during the COVID-19 pandemic. The research design used is qualitative descriptive research. The research informant consisted of Tabanan I Puskesmas Officer, Village Midwife, Posyandu Cadre, Village Head and Toddler Mother. Data collection techniques with in-depth interviews and observations. This research was conducted during April to May 2021. Data analysis uses thematic analysis and data validation strategies using source triangulation, method triangulation and peer debriefing. The results showed that strategy of implementing Posyandu Balita was conducted with a home visit to monitor the growth of toddlers. Online media as a tools to dissemination of information about health of toddlers and the implementation of health protocols. Training to improve skills is needed in the development of the implementation strategy of Posyandu Balita during the COVID-19 pandemic.
Keywords: Toodlers Posyandu, COVID-19, monitoring the nutritional status of toodlers, implementation strategies, Community Health Center
ANALISIS TINGKAT KEPUASAN MASYARAKAT TERHADAP MUTU PELAYANAN PUBLIK PADA MASA PANDEMI COVID-19 DI KANTOR BPJS KESEHATAN KABUPATEN BADUNG
Authors: Putri Ayuning Sekar , Listyowati Rina 
Published: April 2022

The social restriction policy due to the COVID-19 pandemic has had an impact on the delay of various public services, one of which is BPJS Health services. In the midst of a pandemic situation, BPJS Kesehatan is required to provide quality services to the community. Therefore, this study aims to determine the level of community satisfaction in terms of five dimensions of service quality, namely Responsiveness, Reliability, Assurance, Empathy, and Tangible. This study uses a quantitative design with a cross-sectional approach. The sample of this study was 100 people who visited the service office, with the sampling technique using the consecutive sampling method. The results of the univariate analysis show the characteristics of the respondents at the BPJS Kesehatan. The majority of respondents are aged between 26 years and 50 years (62.00%), male and female gender are the same (50.00%), bachelor degree (40.00%), working status Private Employee (49.00%), and domiciled from Mengwi District (29.00%). Bivariate analysis using the Chi-square test found that there was a significant relationship between the five dimensions of service quality and community satisfaction (p-value < 0.001). Most respondents are dissatisfied with the services provided at the BPJS Health Office in Badung Regency, so BPJS needs to pay attention to several dimensions that are still not satisfied by respondents, such as the Tangible aspect, so that the quality of service to the community can continue to be improved during the COVID-19 pandemic.
Key words: Community Satisfaction, Public Services, COVID-19 Pandemic
BISPESIFIK IL-17A DAN IL-17F (IL-17A/F) SEBAGAI INOVASI TERAPI TERBARU BAGI PARA PENDERITA PSORIASIS: SEBUAH TELAAH PUSTAKA SISTEMATIS
Authors: Kuatama Rexel , Ruby Rivaldi , Mangkuliguna Ghea 
Published: April 2022

Introduction: Psoriasis is a chronic inflammatory skin disease characterized with redness, scaling, induration, itchiness, and thickness of skin that worsen quality of life, particularly in moderate to severe psoriatic patients. Although the emergence of biologics has provided revolutionary therapy in the management of moderate to severe psoriasis, significant number of patient has shown ineffectiveness. Recent studies suggest the use of bispecific antibodies as an effective and efficient alternatives . This review aims to evaluate the effectiveness and adverse side effects of bispecific IL-17A/F in various clinical studies. Discussion: This paper yields results that ~100% and >80% of patients treated with bispecific IL-17A/F is able to achieve PASI75 and PASI90, respectively, by week 12 in phase I and II studies. Moreover, bispecific IL-17A/F is able to significantly reduce inflammatory response in psoriatic skin biopsies. Only mild treatment-related adverse events is reported and no immunogenicity is detected. Conclusion: Bispecific IL-17A/F provides effective therapy with minimal adverse side effects within a short amount of time. Further study is needed to compare its effectiveness against other biologics.
Keywords: bimekizumab, biologics, bispecific IL17A/F, M1095, psoriasis, systematic review
HUBUNGAN TINGKAT PENGETAHUAN MAHASISWA UNIVERSITAS INDONESIA TERHADAP KEBIASAAN MEROKOK
Authors: Wardhana Indy Larasati , Susanto Agus Dwi 
Published: April 2022

Latar Belakang: Terdapat 35,5% mahasiswa di Indonesia perokok aktif. Mahasiswa harusnya memiliki tingkat pendidikan yang baik. Tingkat pengetahuan merupakan aspek penting yang mampu memengaruhi kebiasaan merokok. Tujuan penelitian ini melihat hubungan tingkat pengetahuan mahasiswa Universitas Indonesia (UI) terhadap bahaya rokok dan kebiasaan merokok. Metode: Metode penelitian ini adalah studi potong lintang yang dilaksanakan di UI pada bulan Agustus 2018-Desember 2019. Peneliti menggunakan kuesioner sebagai instrumen untuk disebarkan kepada 94 responden yang dipilih menggunakan teknik pengambilan acak. Uji yang dilakukan untuk menganalisis data adalah uji fisher. Hasil: Terdapat 9,6% mahasiswa UI yang merupakan perokok aktif dengan mayoritas berjenis kelamin laki-laki (88,9%), berasal dari fakultas hukum (44,4%), menggunakan rokok putih (66,7%), usia awal merokok 17 tahun (33,3%), mengonsumsi 5-10 batang rokok sehari (55,5%), hanya menggunakan rokok konvensional (89%), dan derajat adiksi terhadap nikotinnya ringan. Mayoritas responden memiliki tingkat pengetahuan bahaya rokok yang tinggi (69,1%). Diskusi: Tidak ditemukan hubungan yang bermakna antara tingkat pengetahuan dengan kebiasaan merokok maupun derajat adiksi nikotin. Pengetahuan yang tinggi tidak membuat mahasiswa berhenti merokok karena perokok cenderung menyepelekan bahaya dari merokok terhadap diri sendiri atau sekitarnya. Derajat adiksi nikotin pada mahasiswa UI cenderung ringan. Hal ini menunjukkan bahwa alasan mahasiswa UI merokok bukan disebabkan oleh kecanduan.
KETERKAITAN CARA KERJA KONTRASEPSI HORMONAL DENGAN RISIKO TERJADINYA KANKER PAYUDARA
Authors: Els Vanessa 
Published: April 2022

ABSTRACT
Introduction: Breast cancer has attacked 42.1 per 100,000 female residents in Indonesia with an average mortality rate of 17 per 100,000. One of the risk factors is the usage of hormonal contraceptives which is the main contraceptive option used in Indonesia. There are a number of differences regarding the risk factors for the use of hormonal contraceptives against breast cancer, so this review was created to examine the relationship between how hormonal contraception works and its risk for breast cancer.
Discussion: Breast cancer is a deadly disease common in women, both in developing and developed countries. One of the risk factors considered is the usage of hormonal contraceptives. Most contraceptives consist of estrogen and progesterone. Estrogen and progesterone are important hormones for the development of female reproductive organs and the physiological function of the body including breast. Most studies show an increased risk of breast cancer and some show no association so this issue still causes controversy. The link between hormonal contraceptives and breast cancer should be studied in more detail taking into account other risk factors, breast cancer pathophysiology, and the length of time they are studied.
Conclusion: Estrogen and progesterone found in hormonal contraceptives have several important functions for the body, one of which is the development of physiological functions of several organs in the body including breast. On the other hand, low doses of hormonal contraceptives have minimal effects on breast cancer and there are still many risk factors other than hormonal contraceptives that should be studied.
Pengaruh Konsentrasi Asap Cair Bambu Tabah (Gigantochloa nigrociliata Buse-Kurz) Dan Suhu Pemasakan Terhadap Karakteristik Se’i Tuna
Authors: Meranggi Pande Putu Raditya Premananda , Kencana Pande Ketut Diah , Wirawan I Putu Surya 
Published: April 2022

Abstrak
Ikan Tuna merupakan makanan yang disukai masyarakat karena kaya akan nutrisi sehingga membutuhkan perlakuan berkelanjutan guna menjaga ketahanan mutu yang lebih baik. Upaya yang dapat dilakukan guna menjaga ketahanan mutu yang lebih baik adalah dengan menggunakan metode asap cair. Penggunaan asap cair memiliki banyak keuntungan diantaranya mudah diaplikasikan, dapat memberikan karakteristik khas pada produk berupa kenampakan, aroma, tekstur, rasa yang lebih menarik, dan tidak mencemari lingkungan.Asap cair yang digunakan adalah asap cair bamboo tabah (Gigantochloa nigrociliata Buse-Kurz). Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi asap cair bambu tabah dan suhu pemasakan terhadap karakteristik Se’i Tuna. Metode yang digunakan adalah Rancangan Acak Lengkap Faktorial dengan dua faktor. Faktor pertama adalah konsentrasi asap cair, terdiri dari 2%, 4%, dan 6% dan faktor kedua adalah suhu pemasakan, terdiri dari 80oC, 90oC, dan 100oC. Kombinasi perlakuan terbaik adalah pada konsentrasi asap cair 6% dan suhu pemasakan 100oC, dengan pemanasan selama 4 jam menghasilkan nilai kadar air 50,46%; kadar protein 17%; pH 5,53; kadar abu 2,81%; uji sensori kenampakan 8,07; aroma 8,73; rasa 8,73; dan tekstur 8,60.
Abstract
Tuna fish is a food that people like because it has rich nutrients so it requires continuous treatment to maintain a better quality. To maintain a better quality of tuna fish is using the liquid smoke method. The application of liquid smoke has many advantages among other methods because its easy application, giving the product distinctive characteristics in the form of a more attractive appearance, aroma, texture, taste, and does not pollute the environment. The liquid smoke was used from tabah bamboo (Gigantochloa nigrociliata Buse-Kurz). This study aims to determine the effect of the concentration of liquid bamboo smoke and cooking temperature on the characteristics of Se'i Tuna. The method used was a factorial completely randomized design with two factors. The first factor is the concentration of liquid smoke (consisting of 2%, 4%, and 6%) and the second factor was the cooking temperature (consisting of 80oC, 90oC, and 100oC). The best treatment combination was at a concentration of 6% liquid smoke and a cooking temperature of 100oC by heating for 4 hours, the water content was 50.46%, protein content 17%, pH 5.53, ash content 2.81%, appearance sensory test 8,07, flavor 8,73, taste 8,73, and texture 8,60.
Hubungan antara Penggunaan Alat Pelindung Diri (APD) dengan Keluhan Petani akibat Pestisida (Studi Kasus di Subak Sri Gumana,Desa Rejasa,Kabupaten Tabanan)
Authors: Suwimantara I Made Galih , Sucipta I Nyoman , Tika I Wayan 
Published: April 2022

Abstrak
Penggunaan pestisida tidak sesuai aturan dapat mengakibatkan dampak negatif baik bagi lingkungan maupun kesehatan manusia. Adapun tujuan dari penelitian ini yaitu untuk mengetahui terdapat atau tidaknya hubungan antara penggunaan APD dengan keluhan petani akibat pestisida di Subak Sri Gumana, Desa Rejasa, Kabupaten Tabanan. Sampel pada penelitian ini menggunakan 30 orang (16%) dari jumlah total yaitu 189 orang petani Subak Sri Gumana. Instrumen penelitian menggunakan kuisioner skala likert yang didalamnya memberi pilihan jawaban kepada responden. Berdasarkan hasil yang didapat melalui uji chi-square diketahui nilai p-value yaitu 0.002 (p <0.05), sehingga dikatakan terdapat hubungan antara penggunaan APD dengan keluhan petani akibat pestisida di Subak Sri Gumana, Desa Rejasa, Kabupaten Tabanan. Kesimpulan dari penelitian ini adalah terdapat hubungan antara penggunaan APD dengan keluhan petani akibat pestisida di Subak Sri Gumana, Desa Rejasa, Kabupaten Tabanan. Keluhan yang muncul disebabkan karena dalam pemakaian pestisida, perhatian petani yang masih kurang dalam penggunaan APD dan cenderung mengabaikan dampak negatif dari pestisida.
Abstract
The usage of pesticides that do not by following the rules can give a negative impact on human health and the environment. This study aims to determine a relationship between usage of Personal Protective Equipment (PPE) with farmer complaints due to pesticides in Subak Sri Gumana, Rejasa Village, Tabanan Regency. This study used samples amount 30 people (16%) from 189 farmers in Subak Sri Gumana. The instrument used the questionnaire Likert scale which provides choices for respondents to answer. Based on the result of chi-square test, the p-value is 0.002 (p <0.05), so there was a relationship between usage of Personal Protective Equipment (PPE) with farmer complaints due to pesticides in Subak Sri Gumana, Rejasa Village, Tabanan Regency. The conclusion is found a relationship between the usage of personal protective equipment (PPE) with farmers complaints due to pesticides in Subak Sri Gumana, Rejasa Village, Tabanan Regency. These complaints arise because farmers haven’t used Personal Protective Equipment (PPE) and ignore the dangers of using pesticides.