bluuebunny/crossref_metadata_2025_split huggingface dataset:
Розлади психологічних рис особистості, сну та варіабельності серцевого ритму в осіб різного віку з метаболічним синдромом
Authors: Денефіль О. В. , Кліщ І. М. , Криницька І. Я. 
Published: November 2022

Резюме. За останні роки з’явилося багато статей, що вказують на взаємозв’язок тривалості сну з розвит­ком метаболічного синдрому. Розлади сну є облігатними властивостями депресії, що може супроводжуватися порушеннями з боку регуляторних впливів автономної нервової системи (АНС) на серцеву діяльність.
Мета дослідження – виявити особливості психологічних рис особистості, сну та варіабельності серцевого ритму в осіб різного віку з метаболічним синдромом.
Матеріали і методи. Обстежено дві групи людей: 18–21 рік (перша група) і 60–74 роки (друга група). До першої групи увійшло 12 осіб чоловічої і 14 осіб жіночої статей із надмірною масою тіла, з обводом талії більше від норми, підвищеним артеріальним тиском і рівнем глюкози крові натще понад 5,6 ммоль/л. Дана група осіб не приймала ліків, щоб відкорегувати метаболічний синдром. До другої групи увійшло 16 чоловіків і 22 жінки, які мали підтверджений метаболічний синдром і приймали відповідне медикаментозне лікування. Усім проводили анкетування за допомогою багатофакторного особистісного опитувальника FPI форми В, варіаційну кардіоінтервалометрію та опитування щодо режиму сну.
Результати. Встановлено особливості психологічних рис особистості, тривалості та якості сну, регуляторних механізмів серцевою діяльністю з боку АНС.
Висновки. За результатами опитувальника FPI форми В встановлено, що у молодих чоловіків, порівняно з жінками, менші невротичність і депресивність, більші спонтанна й реактивна агресивність, урівноваженість, екстравертованість, маскулінність. У чоловіків зрілого віку, порівняно з жінками, виявлено менші невротичність, депресивність, більші спонтанна агресивність, урівноваженість, екстравертованість. У чоловіків другої групи, порівняно з першою, більші невротичність, депресивність, сором’язливість. У жінок другої групи, порівняно з першою, переважають депресивність, дратівливість, сором’язливість, інтровертованість. У двох групах обстежених тривалість сну менша ніж 6 год: у молодих осіб за рахунок неспання у вечірньо-нічні години, а у зрілих – за рахунок ранкових. За результатами спектрального аналізу серцевого ритму встановлено, що у чоловіків першої групи адекватна реакція регуляції серцевого ритму АНС, а другої групи – недостатня реакція з боку симпатичного відділу АНС, у жінок першої і другої груп відмічено гіперреактивну реакцію, а також більші регуляторні впливи АНС.
Cardiac Resynchronization Therapy for Adult Patients With a Failing Systemic Right Ventricle: A Multicenter Study
Authors: Kharbanda Rohit K. , Moore Jeremy P. , Lloyd Michael S. , Galotti Robert , Bogers Ad J. J. C. , Taverne Yannick J. H. J. , Madhavan Malini , McLeod Christopher J. , Dubin Anne M. , Mah Douglas Y. , Chang Philip M. , Kamp Anna N. , Nielsen Jens C. , Aydin Alper , Tanel Ronn E. , Shah Maully J. , Pilcher Thomas , Evertz Reinder , Khairy Paul , Tan Reina B. , Czosek Richard J. , Shivkumar Kalyanam , de Groot Natasja M. S. 
Published: November 2022

Background
The objective of this international multicenter study was to investigate both early and late outcomes of cardiac resynchronization therapy (CRT) in patients with a systemic right ventricle (SRV) and to identify predictors for congestive heart failure readmissions and mortality.

Methods and Results

This retrospective international multicenter study included 13 centers. The study population comprised 80 adult patients with SRV (48.9% women) with a mean age of 45±14 (range, 18–77) years at initiation of CRT. Median follow‐up time was 4.1 (25th–75th percentile, 1.3–8.3) years. Underlying congenital heart disease consisted of congenitally corrected transposition of the great arteries and dextro‐transposition of the great arteries in 63 (78.8%) and 17 (21.3%) patients, respectively. CRT resulted in significant improvement in functional class (before CRT: III, 25th–75th percentile, II–III; after CRT: II, 25th–75th percentile, II–III;
P
=0.005) and QRS duration (before CRT: 176±27; after CRT: 150±24 milliseconds;
P
=0.003) in patients with pre‐CRT ventricular pacing who underwent an upgrade to a CRT device (n=49). These improvements persisted during long‐term follow‐up with a marginal but significant increase in SRV function (before CRT; 30%, 25th–75th percentile, 25–35; after CRT: 31%, 25th–75th percentile, 21–38;
P
=0.049). In contrast, no beneficial change in the above‐mentioned variables was observed in patients who underwent de novo CRT (n=31). A quarter of all patients were readmitted for heart failure during follow‐up, and mortality at latest follow‐up was 21.3%.

Conclusions
This international experience with CRT in patients with an SRV demonstrated that CRT in selected patients with SRV dysfunction and pacing‐induced dyssynchrony yielded consistent improvement in QRS duration and New York Heart Association functional status, with a marginal increase in SRV function.
Final 5‐Year Report of the Randomized BIO‐RESORT Trial Comparing 3 Contemporary Drug‐Eluting Stents in All‐Comers
Authors: Ploumen Eline H. , Pinxterhuis Tineke H. , Buiten Rosaly A. , Zocca Paolo , Danse Peter W. , Schotborgh Carl E. , Scholte Martijn , Gin R. Melvyn Tjon Joe , Somi Samer , van Houwelingen K. Gert , Stoel Martin G. , de Man H. A. F. , Hartmann Marc , Linssen Gerard C. M. , van der Heijden Liefke C. , Kok Marlies M. , Doggen Carine J. M. , von Birgelen Clemens 
Published: November 2022

Background
In a previous trial, higher 5‐year mortality was observed following treatment with biodegradable polymer Orsiro sirolimus‐eluting stents (SES). We assessed 5‐year safety and efficacy of all‐comers as well as patients with diabetes treated with SES or Synergy everolimus‐eluting stents (EES) versus durable polymer Resolute Integrity zotarolimus‐eluting stents (ZES).

Methods and Results

The randomized BIO‐RESORT (Comparison of Biodegradable Polymer and Durable Polymer Drug‐Eluting Stents in an All Comers Population) trial enrolled 3514 all‐comer patients at 4 Dutch cardiac centers. Patients aged ≥18 years who required percutaneous coronary intervention were eligible. Participants were stratified for diabetes and randomized to treatment with SES, EES, or ZES (1:1:1). The main end point was target vessel failure (cardiac mortality, target vessel myocardial infarction, or target vessel revascularization). Five‐year follow‐up was available in 3183 of 3514 (90.6%) patients. The main end point target vessel failure occurred in 142 of 1169 (12.7%) patients treated with SES, 130 of 1172 (11.6%) treated with EES, versus 157 of 1173 (14.1%) treated with ZES (hazard ratio [HR], 0.89 [95% CI, 0.71–1.12],
P
log‐rank
=0.31; and HR, 0.82 [95% CI, 0.65–1.04],
P
log‐rank
=0.10, respectively). Individual components of target vessel failure showed no significant between‐stent difference. Very late definite stent thrombosis rates were low and similar (SES, 1.1%; EES, 0.6%; ZES, 0.9%). In patients with diabetes, target vessel failure did not differ significantly between stent‐groups (SES, 19.8%; EES, 19.2%; versus ZES, 21.1% [
P
log‐rank
=0.69 and
P
log‐rank
=0.63]).

Conclusions
Orsiro SES, Synergy EES, and Resolute Integrity ZES showed similar 5‐year outcomes of safety and efficacy, including mortality. A prespecified stent comparison in patients with diabetes also revealed no significant differences in 5‐year clinical outcomes.

Registration

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT01674803.
Comparative wood anatomy of 16 Malagasy Dalbergia species (Fabaceae) using multivariate techniques
Authors: Ramanantsialonina Ravo Nantenaina , Crameri Simon , Sandratriniaina Ninah Andrianasolo , Wiemann Michael C. , Hermanson John C. , Rakouth Bakolimalala , Ravaomanalina Bako Harisoa 
Published: November 2022

Summary
Rosewood and palisander (Dalbergia L.f., Fabaceae) are sources of highly valuable tropical timber and include species threatened by habitat degradation and selective logging for national and international trade. Law enforcement depends on reliable and cost-effective species-level identification of timber along the supply chain. The potential of wood anatomy to distinguish between species has not yet been systematically investigated for Dalbergia species from Madagascar. We assessed 36 qualitative and eight quantitative wood anatomical features in 16 Malagasy Dalbergia species that form medium-sized to large trees, representing each species by at least five individuals. We integrated and contrasted the newly collected data with existing data from InsideWood and two previous studies. Principal component analysis of 93 individuals and 29 variables resulted in non-overlapping hulls for eight species with respect to the first two dimensions. Four quantitative features (number of ray tiers per millimetre, number of rays per millimetre, vessel density, and vessel element length) and two qualitative features (scanty paratracheal axial parenchyma and irregular to absent storied structure) were found to be potentially diagnostic to distinguish three single species and three pairs of closely related species. Following our analyses, we provide a provisional microscopic wood anatomical identification key for the 16 Dalbergia species, which can be applied to both logs and sawn wood.
Two new species of Diderma (Physarales, Didymiaceae) from northern China
Authors: ZHAO HUI-NAN , RAO GU , YANG XIN-YA , LI XIAO , YU HAI-LONG , ZHANG BO , LI YU 
Published: November 2022

Diderma is one of the most abundant species in Myxomycetes. Based on the study of morphology and phylogeny, two new species—Diderma liaoningensis (is characterized by grouped sporocarps, the sporocyst with dehiscence lines, capillitium with large brown swelling, spore encircled by a pale line) and Diderma verrucocapillitia (is characterized by depressed plasmodiocarps, verrucose capillitium, red-brown spores)—collected from Liaoning province and Jilin province were introduced. Detailed descriptions and illustrations are presented as well as comparisons to similar species. Phylogenetic analyses were carried out using Maximum Likelihood and Bayesian inference based on small subunit ribosomal RNA sequences (SSU rRNA) of Diderma and related genera. These analyses confirmed the placement of two new species in the genus Diderma. A key to 19 species of Diderma from China is also provided. Holotype specimens have been housed in the Herbarium of the Mycological Institute of Jilin Agricultural University (HMJAU), Changchun, China.
Evaluation of WRF Simulation of Deep Convection in the U.S. Southern Great Plains
Authors: Pryor S. C. , Letson F. , Shepherd T. , Barthelmie R. J. 
Published: November 2022

Abstract
The Southern Great Plains (SGP) region exhibits a relatively high frequency of periods with extremely high rainfall rates (RR) and hail. Seven months of 2017 are simulated using the Weather Research and Forecasting (WRF) Model applied at convection-permitting resolution with the Milbrandt–Yau microphysics scheme. Simulation fidelity is evaluated, particularly during intense convective events, using data from ASOS stations, dual-polarization radar, and gridded datasets and observations at the DOE Atmospheric Radiation Measurement site. The spatial gradients and temporal variability of precipitation and the cumulative density functions for both RR and wind speeds exhibit fidelity. Odds ratios > 1 indicate that WRF is also skillful in simulating high composite reflectivity (cREF, used as a measure of widespread convection) and RR > 5 mm h−1 over the domain. Detailed analyses of the 10 days with highest spatial coverage of cREF > 30 dBZ show spatially similar reflectivity fields and high RR in both radar data and WRF simulations. However, during periods of high reflectivity, WRF exhibits a positive bias in terms of very high RR (>25 mm h−1) and hail occurrence, and during the summer and transition months, maximum hail size is underestimated. For some renewable energy applications, fidelity is required with respect to the joint probabilities of wind speed and RR and/or hail. While partial fidelity is achieved for the marginal probabilities, performance during events of critical importance to these energy applications is currently not sufficient. Further research into optimal WRF configurations in support of potential damage quantification for these applications is warranted.

Significance Statement
Heavy rainfall and hail during convective events are challenging for numerical models to simulate in both space and time. For some applications, such as to estimate damage to wind turbine blades and solar panels, fidelity is also required with respect to hail size and joint probabilities of wind speed and hydrometeor type and rainfall rates (RR). This demands fidelity that is seldom evaluated. We show that, although this simulation exhibits fidelity for the marginal probabilities of wind speed, RR, and hail occurrence, the joint probabilities of these properties and the simulation of maximum size of hail are, as yet, not sufficient to characterize potential damage to these renewable energy industries.
Multimedia Characteristics, Student Relationships, and Teaching Behaviors Predict Perceptions of an Inclusive Classroom Across Course Delivery Format
Authors: Shane-Simpson Christina , Obeid Rita , Prescher Manna 
Published: November 2022

Background Student perceptions of inclusion have been predicted by rapport, and belongingness in face-to-face courses, although these relationships have not been studied across course delivery formats. Objective This study clarified relationships among course multimedia characteristics, student–professor rapport, instructor and student presence, classroom climate, quality of teaching behaviors, and perceptions of an inclusive classroom in varied course delivery formats. Method A total of 479 students from two universities completed an online survey assessing their course delivery format, multimedia characteristics, rapport, instructor and student presence, classroom climate, teaching behaviors, and perceptions of an inclusive classroom. Results Students’ perceptions of inclusion were predicted by course multimedia characteristics (e.g., videos), student–professor rapport, instructor presence, course structure, course clarity, student connectedness, and the quality of teaching behaviors. Conclusion Inclusive classrooms reflect a myriad of instructor-, student-, and classroom-level characteristics and behaviors. However, the predictive value of these characteristics can change based on the course delivery format. Teaching Implications Faculty professional development opportunities for inclusive pedagogy should include skill development for course design (multimedia characteristics, structure), professor–student rapport-building and classroom community building, and high-quality teaching behaviors that align with specific course delivery formats.
Adherence to antimalarials and glucocorticoids treatment and its association with self-reported disease activity in systemic lupus erythematosus patients
Authors: Correa-Rodríguez María , Rueda-Medina Blanca , Callejas-Rubio José-Luis , Ríos-Fernández Raquel , Gil-Gutiérrez Rocío , Ortego-Centeno Norberto 
Published: November 2022

Objectives We aimed to investigate the rate of non-adherence to antimalarials and glucocorticoids (GCs) and to analyze their potential relationships with sociodemographic characteristics, disease activity and accumulate damage in a cohort of Systemic lupus erythematosus (SLE) patients. Methods A cross-sectional study was conducted among 670 patients. The Systemic Lupus Erythematosus Activity Questionnaire (SLAQ) and the Lupus Damage Index Questionnaire (LDIQ) were used to assess disease activity and accumulated damage. Results The prevalence of non-adherence to antimalarials and GCs were 10.67% and 39.61%. 86.9% of participants indicated that the reason for stopping therapy was the presence of side effects. SLE patients with non-adherence to antimalarials and GCs had significantly higher scores in disease severity (SLAQ) compared to adherence patients (5.03 (2.12) vs 4.39 (2.61); p = .004 and (4.75 (2.29) vs 4.05 (2.78); p ≤ .001). Conclusion Adherence to the treatment indicated in SLE differs from drug to drug. Findings highlight the importance of developing interventions to support adherence and improve outcomes among patients.
Expression of Shh, Gli1, and Cyr61 in Gastric Cancer Predicts Overall Survival of Patients: A Retrospective Study
Authors: Quan Xiaoling , Zhang Zhenming , Qin Yujie , Gai Xin , Tian Qiling , Guo Yaqiong , Qian Jun , Yao Jiaxi 
Published: November 2022

Objective This study aimed to evaluate the expression levels of Shh, Gli1, and Cyr61 proteins in gastric cancer tissues and analyze the relationship between these three proteins and the clinicopathological factors and prognosis of patients. Methods This was a retrospective study. Four hundred gastric cancer tissue specimens from patients who underwent radical gastrectomy in Zhangye People’s Hospital affiliated to Hexi University between February 2013 and February 2021 underwent immunohistochemical analysis. Results The positive expression rates of Shh, Gli1, and Cyr61 in gastric cancer tissues were 55.5%, 56.5%, and 64.5%, respectively. The expressions of Shh, Gli1, and Cyr61 in gastric cancer tissues were significantly correlated with tumor size, depth of invasion, and degree of differentiation (P < .05). The expression of Shh protein was positively correlated with the expression of Gli1 protein (P < .01), and the expression of Gli1 protein was positively correlated with the expression of Cyr61 protein (P < .01). Univariate and multivariate analyses showed that the expression of Shh, Gli1, and Cyr61 could predict the prognosis of patients (P < .05). Receiver operating characteristic curve analysis combined with TNM staging could better predict the three-year overall survival of patients (P < .05). Conclusion Shh, Gli1, and Cyr61 proteins are significantly expressed in gastric cancer tissues and are risk factors for the prognosis of patients with gastric cancer.
Prioritising enhancements across allied health telehealth services in a metropolitan hospital: Using a concept mapping approach
Authors: Burns Clare L , Cottrell Michelle , Jones Amber , Foley Jasmine , Rahmann Ann , Young Adrienne , Cruickshank Mark , Pateman Kelsey 
Published: November 2022

Introduction A prior study examining perceptions of Allied Health Professions (AHP) telehealth services at a metropolitan hospital highlighted multiple issues impacting service uptake, operationalisation, and delivery. Concept mapping methodology was utilised to address these issues and prioritise actionable telehealth service improvements. Methods Representatives ( n = 22) from seven AHP departments and consumers generated statements addressing the question: ‘What do we need to do to enhance and sustain telehealth services?’ Statements were synthesised and then clinicians and managers sorted them into similar groups and assigned each statement a ranking of perceived (a) importance and (b) changeability. Multivariate and multidimensional scaling was undertaken to develop a final prioritised set of goals for change. Results Ninety-six unique statements were generated as actionable goals for change. Statements were grouped into 13 clusters relating to improvements in staff support, infrastructure, consumer support and organisational processes. All clusters were rated >50% for importance (range 3.3–2.4 out of 4) and changeability (range 2.6–2.1 out of 4). Twenty-six statements were ranked highest for importance and changeability. Key prioritised areas were staff training, consumer advocacy and engagement, telehealth operations and workflow. Conclusion Concept mapping was an effective process for generating a prioritised list of actions to enhance AHP telehealth services.
The Mediating Role of Sexual Self-Efficacy on Protected Sex
Authors: Torregosa Marivic , Patricio Orlando 
Published: November 2022

Background: Ascribed traditional gender role has rarely been examined in the topical area of protected sex. Objective: The purpose of this study was to examine the relationship between HIV knowledge, ascribed cultural gender roles of machismo and marianismo, acculturation, attitudes toward risky sexual behaviors and sexual self-efficacy on protected sex, and the mediating effect of sexual self-efficacy between these predictors and protected sex. Methods: Part of a larger study, Hispanic college students from a Hispanic-serving institution in a U.S. southern border city were recruited. Results and Conclusion: Sexual self-efficacy was found a significant mitigating factor against sexual risks associated with machismo as well as a positive reinforcing element on attitudes toward protected sex. Study findings have implications toward the development of culturally sensitive evidence-based interventions that promote sexual self-efficacy skills among Hispanic males who strongly identify with culturally ascribed gender roles.
Physcomitrium patens CAD1 has distinct roles in growth and resistance to biotic stress
Authors: Jiang Shan , Tian Xu , Huang Xiaolong , Xin Jiankang , Yan Huiqing 
Published: November 2022

Abstract
Background
Physcomitrium patens provides an evolutionary link between green algae and vascular plants. Although the genome of P. patens includes orthologs of all the core lignin biosynthetic enzymes, the occurrence of lignin in moss is very controversial. Besides, little information is available about the lignin enzymes in moss to date. For example, cinnamyl alcohol dehydrogenase (CAD) is a crucial enzyme that catalyzes the last step of the lignin biosynthetic pathway, suggesting an ideal way to study the evolutionary process. By investigating the functions of CAD in evolution, this study will elucidate the evolutionary roles of lignin-like in the early stage of land colonization.

Results
CAD multigene family in P. patens is composed of four genes. The PpCADs contain a conserved glycine-rich domain to catalyze NADPH-dependent reduction to their corresponding alcohols, indicating that PpCADs have the potential to synthesize monolignols by bioinformatics analysis. Even though PpCAD1 could produce lignin in theory, no conventional monomer was detected in the cell wall or cytoplasm of PpCAD1_OE plants. However, the phenylpropanoids were promoted in PpCAD1_OE transformants to modify gametophore architecture and development, making the distribution of phyllids more scarcity and the moss colony more giant, possibly due to the enhanced expression of the AUX-IAA family. The transcripts of at least one gene encoding the enzyme in the lignin biosynthetic pathway were increased in PpCAD1_OE plants. In addition, the PpCAD1_OE gametophore inhibited the Botrytis cinerea assault mainly by enhanced phenylpropanoids in the cell wall instead of influencing transcripts of defense genes pathogenesis-related 10 (PR10) and nonexpresser of PR genes 1 (NPR1). Likewise, ectopic expression of PpCAD1 in Arabidopsis led to a significant increase in lignin content, exhibiting chunky roots, robust seedlings, advanced flowering, and efficient resistance against pathogens.

Conclusion
PpCAD occurs in more than one copy, suggesting functional divergence in the ancestral plant. PpCAD1 catalyzes monolignol biosynthesis and has homologous functions with vascular plants. Despite no detected conventional monolignol, the increased phenylpropanoids in the PpCAD1_OE gametophore, possibly intermediate metabolites in the lignin pathway, had conserved functions during the evolution of terrestrial plants. The results inferred that the lignin enzyme of the early non-vascular plant played roles in stem elongation and resistance against pathogens of P. patens during the conquest of land.