bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences in prophylactic performance across wound dressing types used to protect from device‐related pressure ulcers caused by a continuous positive airway pressure mask
Authors: Orlov Aleksei , Gefen Amit 
Published: September 2022

AbstractProlonged use of continuous positive airway pressure masks, as often required for non‐invasive ventilation, involves a risk for facial tissue breakdown due to the sustained deformations caused by tightening of the stiff mask surfaces to the head and the moist environment. The risk of developing mask‐related facial injuries can be reduced through suitable cushioning materials placed at the skin‐mask interfaces to spread the localised contact forces and disperse the surface and internal tissue stresses. Using an integrated experimental‐computational approach, we compared the biomechanical protective performance of three popular foam‐based wound dressings to that of a market‐lead hydrocolloid dressing when applied to protect the facial skin under a mask. We measured the compressive stiffness properties of the four commercial dressing types in dry and moist conditions, and then fed those to an anatomically realistic finite element model of an adult male head, with an applied simulated mask. Through this process, we calculated the protective efficacy index of each dressing type, indicating the relative contribution of the specified dressing to alleviating facial soft tissue loads with respect to the no‐dressing case. The foam‐based dressings generally performed substantially better than the hydrocolloid, but foam dressings were also demonstrated to vary by their protective performance.
Subclinical sinus node dysfunction in patients with atrial fibrillation—Insight from ultrahigh‐resolution mapping of human sinoatrial exits
Authors: Eguchi Tomoya , Miyazaki Shinsuke , Tsuji Toshihiko , Nagao Moeko , Kakehashi Shota , Mukai Moe , Sekihara Takayuki , Aoyama Daisetsu , Nodera Minoru , Hasegawa Kanae , Uzui Hiroyasu , Tada Hiroshi 
Published: September 2022

AbstractBackgroundEven a short duration of paroxysmal episodes of atrial fibrillation (AF) is associated with sinus node (SN) remodeling and a reduced SN reserve or dysfunction. The number of earliest atrial activation sites (EASs) during sinus rhythm decreases according to the decrease in the SN reserve.ObjectiveWe sought to evaluate the EASs during sinus rhythm using an ultrahigh‐density mapping system.MethodsThis study included 35 patients (supraventricular tachycardia [SVT]/paroxysmal atrial fibrillation [PAF]/persistent atrial fibrillation [PsAF] = 5/21/9) who underwent ultrahigh‐resolution endocardial mapping of the SN area at rest and during β‐stimulation. The number of EASs was determined by the Lumipoint™ algorithm.ResultsThe number of EASs was greatest in SVT patients both at rest (SVT/PAF/PsAF = 1.4 ± 0.8/1.0 ± 0/1.0 ± 0, p = .04) and during β‐stimulation (SVT/PAF/PsAF = 2.6 ± 1.0/1.3 ± 0.6/1.0 ± 0, p < .01). The number significantly increased with β‐stimulation as compared to baseline in the PAF patients (p = .02), but not in the PsAF patients. The brain natriuretic peptide (BNP) level was significantly higher in AF than SVT patients (SVT/PAF/PsAF = 12.3 [10.1–14.5]/25.7 [14.8–36.0]/73.4 [57.6–140] pg/ml, p < .01). In the PAF patients, the BNP level was significantly higher in those with unicentric EASs than multicentric EASs during β‐stimulation (28.1 [19.1–46.5] vs. 13.1 [9.4–26.9] pg/ml, p = .03), and the optimal cutoff point for the BNP level predicting unicentric EASs was 21.8 pg/ml (sensitivity 82.6%; specificity 85.7%).ConclusionsAF patients have a smaller number of EASs and poorer response to β‐stimulation than non‐AF patients. An elevated BNP level might predict subclinical SN dysfunction in patients with PAF.
Pairwise interaction Markov model for 3D epidermal nerve fibre endings
Authors: Konstantinou Konstantinos , Särkkä Aila 
Published: September 2022

AbstractIn this paper, the spatial arrangement and possible interactions between epidermal nerve fibre endings are investigated and modelled by using confocal microscopy data. We are especially interested in possible differences between patterns from healthy volunteers and patients suffering from mild diabetic neuropathy. The locations of the points, where nerves enter the epidermis, the first branching points and the points where the nerve fibres terminate, are regarded as realizations of spatial point processes. We propose an anisotropic point process model for the locations of the nerve fibre endings in three dimensions, where the points interact in cylindrical regions. First, the locations of end points in are modelled as clusters around the branching points and then, the model is extended to three dimensions using a pairwise interaction Markov field model with cylindrical neighbourhood for the z‐coordinates conditioned on the planar locations of the points. We fit the model to samples taken from healthy subjects and subjects suffering from diabetic neuropathy. In both groups, after a hardcore radius, there is some attraction between the end points. However, the range and strength of attraction are not the same in the two groups. Performance of the model is evaluated by using a cylindrical version of Ripley's K function due to the anisotropic nature of the data. Our findings suggest that the proposed model is able to capture the 3D spatial structure of the end points.
Severe persistent urticaria following laser hair reduction
Authors: Dorgham Noelle , Witkoff Benjamin , Weiss Eduardo , Glick Brad 
Published: September 2022

AbstractBackgroundLaser hair reduction is a common practice that utilized light‐based therapy to prevent future hair growth. Complications following laser hair reduction treatment include thermal burns, which may lead to hyper‐ or hypopigmentation, hair stimulation, scar, or transient erythema of treated areas.AimsReview reports of persistent urticaria following laser hair reduction and discuss a rarely discussed laser complication.MethodsPubmed literature review.ResultsThere have been very rare reports of persistent urticaria following laser hair reduction. Similar case reports have also been described though no definitive reasoning for this reaction, nor consistent treatment has been documented.DiscussionIn this report, we present a patient who developed persistent urticaria with severe pruritus in the areas treated with laser hair reduction. Previous reports an association was found between allergies and post‐treatment urticarial eruption, with 33/36 patients having allergies, mostly to dust mites which is similar to the patient presented. Other etiologies such as reaction to cryogen and physical urticaria are unlikely.ConclusionOur report highlights a case of persistent urticaria with severe pruritus following laser hair reduction treatment, with both similarities and differences to other cases reported in the literature. While this is a rare side effect of laser hair removal, it should be monitored in patients who have a history of moderate to severe environmental allergies.
Case report of possible iatrogenic Cushing's disease with low‐dose prednisone to treat dermal filler hypersensitivity
Authors: Grillo Ricardo 
Published: September 2022

AbstractObjectivesThe aim of this article is to report a case of iatrogenic Cushing's disease associated with a delayed inflammatory response due to a facial dermal filler procedure.MethodsA case report according to CARE guidelines was performed. A delayed inflammatory reaction due to dermal filler injection resulted in iatrogenic Cushing's disease in a patient with no comorbidities or allergies.ResultsProlonged use of glucocorticoids can cause adverse effects, such as iatrogenic Cushing's disease. Dermal fillers have a very low incidence of complications, but these need to be discussed with patients. Drugs used to treat delayed inflammatory reaction include antibiotics, antihistamines, steroids, and intralesional hyaluronidase. Reversal of dermal fillers should be explained to the patient and included in the written consent.ConclusionsDue to patient non‐compliance and possible adverse effects of steroid medications, physicians should consider limiting their prescriptions of steroid medications to no more than 2 weeks and require frequent follow‐up to discuss hyaluronidase if the condition returns off of steroid medication. In addition, it may be advisable to only treat with one filler brand, especially in the same session as this may be a risk factor.
Race, Gender, and the Relationship Between Religious Factors and Verbal Ability: An Intersectional Approach
Authors: Sherkat Darren E. 
Published: September 2022

AbstractThe negative relationship between religiosity and cognitive ability is well documented though most research on the connection between religion and cognitive factors has largely ignored how social positions like race and gender may inform the association. This paper explores how race and gender intersect with the association between religious factors and verbal ability. Using data from the General Social Surveys, I examine racial differences in the impact of religious identification, religious participation, and beliefs about the Bible on verbal ability. The analyses show that the association between religious factors and verbal ability varies significantly across racial groups, and points to some gender differences in the association between religious factors and verbal ability by race. The findings highlight the importance of an intersectional approach and suggest that psychological theorizing about the relationships between religion and cognitive ability is underdeveloped.
Poly‐β‐hydroxybutyrate concentration, microbial enzymes activity, and nutritional value in biofloc system using different carbon sources and C/N ratios in common carp, Cyprinus carpio culture
Authors: Najdegerami Ebrahim H. , Tukmechi Amir 
Published: September 2022

AbstractThis experiment was designed with three carbon sources (Dextrin, wheat bran, and corn starch), each with two carbon to nitrogen (C/N) ratios (19 and 30) for 4 weeks. The data obtained from two variables (carbon sources, C/N ratio) were analyzed with a two‐way analysis of variance. At the end of the experiment, the results indicated that the use of varying carbon sources and C/N ratios significantly changed the nutritional value of microbial flocs (p < 0.05). Also, the results showed that both variables significantly affected the main groups of saturated, mono‐unsaturated, and polyunsaturated fatty acids in the microbial flocs (p < 0.05). Dextrin flowing corn starch at a low C/N ratio significantly increased poly‐β‐hydroxybutyrate accumulation in microbial flocs (p > 0.05). The microbial enzyme profile changed in all carbon sources but C/N ratios did not affect microbial enzymes in the treatments except in a significantly higher value for amylase and acidic protease activity at a C/N ratio of 30 (p < 0.05). Also, at the end of the experiment, total bacteria and Lactobacillus count were affected by carbon sources and the highest density was observed in wheat bran and Dextrin respectively. These findings may encourage farmers to consider specific carbon sources and C/N ratios based on culture conditions and species requirements.
Evaluation of modified C‐palatal plates on speech articulation using acoustic analysis
Authors: Joo Mun Chan , Bayome Mohamed , Kang Seok Jae , Ham Lyun Kwang , Lee Nam‐Ki , Park Jae Hyun , Kook Yoon‐Ah 
Published: September 2022

AbstractIntroductionThe purpose of this study was to assess speech perturbation and adaptation for patients wearing modified C‐palatal plates (MCPPs) over time.MethodsThe sample consisted of 40 patients, 20 wearing MCPPs as the experimental group (age: 20.7 ± 5.8 years) and 20 patients wearing a transpalatal arch (TPA) as the control group (age: 21.5 ± 6.4 years). The sounds /t/, /d/, /s/, /n/, /r/, /tʃ/. and /j/ were recorded for each patient at six time points: immediately before (T0) and after (T1) appliance placement; then 1, 2, 3 and 4 weeks after placement (T2–T5). Acoustic analysis of pitch and voice onset time (VOT) was performed by Praat software. Repeated measures analysis of variance (RM‐ANOVA) was used to assess changes in the pitch and VOT over time and the difference between the appliances.ResultsWith the MCPP appliance, /n/, /r/, /tʃ/ and /j/ decreased in VOT starting in the first week while /t/ and /s/ almost returned to pre‐treatment levels after 2 weeks. VOT for the /d/ sound did not change between T0 and T3, but it decreased after 3 weeks. There were no significant differences in pitch and VOT between the two groups at any time point.ConclusionsWearing an MCPP device caused patients to initially distort the articulation of several sounds, but the distortion dissipated within 1 to 2 weeks. It is recommended that patients and/or their parents be advised during pre‐treatment counselling of the possibility of temporary speech changes with MCPP placement.
Against the inside out argument
Authors: Seymour Amy 
Published: September 2022

AbstractBailey (2021) offers a clever argument for the compatibility of determinism and moral responsibility based on the nature of intrinsic intentions. The argument is mistaken on two counts. First, it is invalid. Second, even setting that first point aside, the argument proves too much: we would be blameworthy in paradigm cases of non‐blameworthiness. I conclude that we cannot reason from intentions to responsibility solely from the “inside out”—our possessing a blameworthy intention cannot tell us whether this intention is also blameworthy in deterministic worlds.
Study on the expression patterns and function of JUNO and CD9 in bovine oocytes during in vitro maturation
Authors: Yang Baigao , Hao Tong , Yang Sha , Hao Haisheng , Du Weihua , Zhu Huabin , Zhang Peipei , Zhao Xueming 
Published: September 2022

AbstractFertilization proteins JUNO and CD9 play vital roles in sperm‐egg fusion, but little is known about their expression patterns during in vitro maturation (IVM) and their function during in vitro fertilization (IVF) of bovine oocytes. In this study, qRT‐PCR and immunofluorescence staining were used to detect the mRNA and protein expression levels of JUNO and CD9 genes in bovine oocytes and cumulus cells. Then, fertilization rate of MII oocytes treated with (i) JUNO antibody (1, 5 and 25 μg/ml) or (ii) CD9 antibody (1, 5 and 25 μg/ml) or (iii) CD9 antibody (5 μg/ml) + JUNO antibody (5 μg/ml) were recorded. Our results showed that the mRNA and protein expression levels of JUNO and CD9 genes significantly increased from bovine GV oocytes to MII oocytes, and similar mRNA expression patterns of JUNO and CD9 were also detected in cumulus cells. All groups of oocytes treated with CD9 antibody or JUNO antibody showed significantly decreased fertilization rates (p < .05). Particularly, the fertilization ability of oocytes treated with CD9 antibody (5 μg/ml) + JUNO antibody (5 μg/ml) sharply decreased to 3.48 ± 0.11%. In conclusion, our study revealed the expression levels of JUNO and CD9 genes in oocytes and cumulus cells increased during IVM of bovine oocytes, with JUNO protein playing a major role in the fertilization of bovine oocytes.
Parents’ and friends’ responses to discrete negative emotions: Associations with adolescent emotional experiences
Authors: Miller‐Slough Rachel L. , Zhu Danhua , Garner Pamela W. , Dunsmore Julie C. 
Published: September 2022

AbstractEmotion socialization (ES) impacts a range of youth socioemotional outcomes. However, research often examines parent socialization of negative emotions more broadly. Research examining multiple socializers demonstrates that variety in ES messages may promote flexibility in youth socio‐emotional adjustment. The current study examined how parents’ and friends’ supportive socialization of discrete negative emotions (anger, sadness, worry) related to adolescents’ emotional experiences. Eighty‐seven adolescents (50 girls; 13–15 years old, M age = 14.23 years) reported on parent and friend supportive ES in 8th grade. Sixty‐four of these adolescents reported their own emotional experiences in 9th and/or 10th grade. Parents’ supportive ES was higher than friends’ for sadness and worry. Divergence between parent and friend ES of sadness related to lower increases in anger over time. There were effects of convergence in ES of anger, as matches between parent and friend ES were related to less experience of all three negative emotions. There were unique effects of parent and friend ES of worry. Parent ES of worry related to adolescents’ balance of anger and sadness, whereas friend ES of worry related to decreased sadness over time. These findings suggest that ES and its relations with adolescent emotional experience varied by discrete emotions, as each carries a different meaning and function. Future research should examine processes connecting discrete emotional experiences within interactions and across time.
An Efficient Analytical Method Based on Averaging and Memory-Free Principle for Variable Fractional Oscillators
Authors: Liu Q. X. , Liu J. K. , Chen Y. M. 
Published: September 2022

Abstract
It has been a difficult task to solve fractional oscillators analytically, especially when variable-order fractional derivatives (FDs) are included. The major difficulty consists in deriving analytical expressions for the variable FDs of trigonometric functions. To tackle this problem, a memory-free transformation for constant-order FDs is modified to transform the variable FDs equivalently into a nonlinear differential equation of integer order. Based on the equivalent equation, an analytical solution is obtained for the variable FD, showing nice agreement with numerical results. According to the approximate analytical solution in closed form, the frequency amplitude curve and the backbone line of variable fractional oscillators are determined accurately. In addition, it provides us with convenience in analyzing the primary resonance.
Finding Social Networks Among Online Reviewers for Customer Segmentation
Authors: Park Seyoung , Kim Harrison M. 
Published: September 2022

Abstract
Recently, online user-generated data have emerged as a valuable source for industrial applications. In the consumer product area, many studies analyze online data and draw implications on product design. However, most of them treat online customers as one group with the same preferences, while customer segmentation is a key strategy in conventional market analysis. This paper proposes a new methodology based on text mining and network analysis for online customer segmentation. First, the method extracts customer attributes from online review data. Then, a customer network is constructed based on these attributes and predefined networking rules. For networking, a new concept of “topic similarity” is proposed to reflect social meaning in the customer network. Finally, the network is partitioned by modularity clustering, and the resultant clusters are analyzed to understand segment properties. We validate our methodology using real-world data sets of smartphone reviews. The result shows that the proposed methodology properly reflects the heterogeneity of the online customers in the segmentation result. The practical application of customer segmentation is presented, illustrating how it can help companies design target-customer-oriented products.
Hit-and-run model for Cretaceous–Paleogene tectonism along the western margin of Laurentia
Authors: Tikoff B. , Housen B.A. , Maxson J.A. , Nelson E.M. , Trevino S. , Shipley T.F. 
Published: September 2022

ABSTRACT
The North American Cordillera experienced major contractional deformation during the Cretaceous–Paleogene, which is commonly attributed to normal subduction transitioning to shallow-slab subduction. We provide details of an alternative hit-and-run model, wherein the Insular superterrane obliquely collided with the North American margin from 100 to 85 Ma (the “hit”), followed by northward translation during continued oblique convergence with North America from 85 to 55 Ma (the “run”). This model assumes that the paleomagnetic evidence from the accreted terranes of the northern North American Cordillera, indicating up to thousands of kilometers of northward movement primarily between ca. 85 and 55 Ma, is correct. The hit-and-run model also incorporates new advances: (1) A worldwide plate reorganization occurred ca. 105–100 Ma; and (2) multiple subducted slabs have characterized subduction systems of the North American Cordillera since ca. 120 Ma. Finally, we explicitly address along-strike variations, such as the role of the preexisting rifted Precambrian margin and Permian–Triassic truncation of North America, in margin-parallel movement along western North America.
The 100–85 Ma “hit” phase of the orogeny was characterized by dextral transpressional deformation that occurred simultaneously in the magmatic arcs of Idaho, northern Nevada, eastern California, and the Peninsular Ranges of southern California and northern Mexico. The hit phase also recorded incipient plateau formation, foreland block uplifts in the northern Rocky Mountains, and significant foreland sedimentation in adjacent North America. The transition from “hit” to “run” is hypothesized to have occurred because of the clockwise rotation of a Precambrian promontory in Washington State that was blocking northward translation: This rotation was accommodated by sinistral motion along the Lewis and Clark deformation zone. The 85–55 Ma “run” phase resulted in dextral strike-slip faulting of coastal blocks and significant contractional deformation in adjacent continental North America. The hit-and-run model is consistent with first-order geological and geophysical constraints from the North American Cordillera, and the proposed type of oblique orogeny requires a three-dimensional, time-dependent view of the deformation along an irregular and evolving continental margin.
‘I felt forced to find an alternative’: a qualitative analysis of women medical educators’ narratives of career transitions
Authors: Eghosa-Aimufua Osa , Boam Alicia , Webb Katie Louise , Browne Julie 
Published: September 2022

ObjectivesWhile institutional and systemic attempts to increase women’s participation in medical education have enabled increasing numbers to enter the field and achieve more senior positions, little is known about lived experiences of female clinical educators. Women clinicians are more likely to change careers and work less than full time. This study focuses on women medical educators’ narratives of career change, with the aim of exploring the interplay between factors affecting career decision-making, career trajectory and professional development. MethodsWe employed narrative enquiry approaches to two data sources (55 written accounts of turning points; 9 semistructured interviews reflecting on periods of career transition). Through analysing themes within each dataset before comparing and contrasting datasets simultaneously, we identified three areas of inconsistency and tension.ResultsParticipants reported feeling both drawn and pushed into medical education. Some respondents reported that they were compelled by circumstances to enter medical education. Participants’ narratives were ambiguous regarding personal and professional identities. Additionally, participants asserted their position as autonomous agents while acknowledging their powerlessness when encountering organisational, social and cultural expectations limiting the ability to make independent choices. Even where primary decisions to pursue medical education were positive and motivated by interest, subsequent disappointments and challenges led some participants to doubt their choices.ConclusionsCareer advancement in medical education may involve women taking significant personal or career sacrifices, partly due to the continued existence of a medical culture allowing men to dominate senior ranks. Women medical educators achieving satisfying senior roles in the field may harbour lingering regret and resentment at the personal and career costs.