bluuebunny/crossref_metadata_2025_split huggingface dataset:
The application of motion capture technology in a clinical evaluation and a therapy for people with autism spectrum disorder
Authors: Baasansuren S. , Kaźmierczak D. , Świątko M. , Krysta K. 
Published: February 2022

IntroductionAutism spectrum disorder (ASD) encopasses disorders with incompletely known etiology. Facial expression of people with ASD does not often reflect their emotions adequately or are strongly limited. In addition, they have a problem with joint attention. The symptoms of autism spectrum disorder are very various and have different severity that can change over time.There are still no objective methods for estimating these symptoms, which creates a huge diagnostic and clinical problem. Motion Capture technology makes the possibility of this objective assessment of the severity of initial symptoms, their change over time, as well as specificity for people with ASD.ObjectivesTo assess the application of Motion Capture technology in a clinical evaluation and a therapy for people with ASD.MethodsWe analyzed literature related to the topic available at medical bases: PubMed, ResearchGate and Google Scholar. The articles which were included had been published after 2000 and have an English or Polish abstract.ResultsWe included 2 trials involving 81 participants (children and adolescents): 1 trial reported on quantifying the social symptoms of autism and 1 trial on differences of facial expressions in people with and without ASD.ConclusionsThis capture of motions and the analysis of specific movements of people with autism spectrum disorder might be very useful in clinical practice, scientific research, therapy and also in creation of functioning systems at homes, schools and kindergartens. Thanks to this, people with ASD will be able to function better in society.DisclosureNo significant relationships.
Instagram, the new ally of Pro-Ana and Pro-Mia
Authors: Jordan G. Lladó , García M.D.C. Díaz , Sánchez P. Mediavilla , Díez B. Lozano , Del Barrio J.A. Gómez , Ayesa-Arriola R. 
Published: February 2022

IntroductionNowadays Social Networks (SN) are used not only in a playful way but also as a ‘health’ means of communication. The Pro-Ana and Pro-Mia accounts or profiles -whereby Eating Disorders are advocated as a ‘lifestyle’- increased by 300% over the last decade.ObjectivesTo analyze Instagram Pro-Ana and Pro-Mia accounts and compare them with Pro-Ana and Pro-Mia Blogs.MethodsA non-computerized research of Pro-Ana and Pro-Mia Blogs and Instagram profiles was performed. Accepting a risk of Alpha=0.05 and Beta=0.15 in a two-tailed test, 29 subjects were required in each group to detect a difference equal to or greater than 0.2 units. The common standard deviation is assumed to be 0.25. Publication averages, photos, opening years, WhatsApp links and number of followers were analysed and compared. Transversal descriptive study.ResultsBlogs: 100% had no groups in other SN, 33.33% had been opened for more than 3 years, 30% included personal pictures, 16.67% contained Ana in their title, 53.3% named other Blogs. Instagram: 56.67% included personal pictures, 13.33% mentioned WhatsApp groups, 73.33% had a public profile, 43.33% contained ‘Ana’ in their user name and 53.33% had more than one hundred followers.ConclusionsThese tools are constantly adapting to the times in which they coexist. There has also been a current increase in Instagram profiles. This study shows a greater linkage to WhatsApp groups on Instagram than on Blogs, together with a higher number of followers, ease of ownership and difficulty of control.DisclosureNo significant relationships.
Birth asphyxia and its implications for neuropsychology and brain volume in schizophrenia
Authors: Wortinger L. , Jørgensen K. , Barth C. , Agartz I. 
Published: February 2022

IntroductionNewborn infants can suffer permanent brain damage as a result of birth asphyxia (ASP), a severe obstetric complication (OC). However, effects of OCs on cognitive abilities and brain structure in schizophrenia (SZ) are unknown.ObjectivesThe main goals of this study were to investigate putative effects of a history of OCs on adult cognition and brain structure in SZ.MethodsWe utilized prospective data from the Medical Birth Registry of Norway to identify incidences of severe OCs in adult healthy controls (HC; n = 622) and patients with SZ (n = 607). IQ was assessed, and a subset of participants (n= 414) underwent magnetic resonance imaging.ResultsSevere OCs (27%) and ASP (14%) were equally common in SZ and HC. SZ patients with OCs had lower IQ than patients without OCs, a difference not found in HC (p = .023). Having experienced more than one co-occurring severe OC was associated with lower IQ in both groups, wherein 81% of co-occurring OCs involved ASP. ASP was related to smaller intracranial volume and brain volumes in both groups. Smaller caudate volumes were found in SZ patients with ASP compared to patients without ASP, a difference not found in HC (p = .009).ConclusionsOur findings give support for an effect of birth ASP on brain development in both patients with SZ and HC. OC history specifically impacts IQ in SZ. Smaller caudate volumes might be particularly related to disease development. These results warrant replication in an independent sample.DisclosureNo significant relationships.
Why is it important to involve people with lived experience in the development of the educational programs in suicide prevention?
Authors: Stensmark M. 
Published: February 2022

Blekinge Family Postvention is a grief facilitator-home-visiting postvention giving early support to families after a suicidal loss since 2015. It helps families overcome shock, pain, anger, guilt, suffering and other extreme emotions caused by suicide. Such situations should be treated not as a disorder. Medication should be used only as a last resort to treat individuals not responding to early family support, followed by individual sessions if needed. Everyone needs to express feelings and thoughts on all aspects of the suddenly interrupted relation. To achieve this, a person experienced in those issues must be leading all of the meetings. The conversations should start during the first days, frequently continuing for at least 3-5 weeks depending on the family needs. Helping the family bear each other and find coping strategies ease their pain, mourning and give them hope instead of prolonged grief. In this way, the family gradually finds new ways to overcome a never-ending negative looping that eventually can cause, e.g. post-traumatic stress disorder and depression. The support to the family after suicide loss should be a governmental matter. Today all work is done voluntarily. The close relatives need debriefing right after the district doctor has stated the death or the police informed the family about suicide. The military, the police, rescue services and healthcare professionals gets debriefing when a rescue operation has failed. This presentation discusses how to organise early family support and the Ellipse project’s interviews with survivors about their experiences of needed or received support if any.DisclosureDISCLAIMER The E-Lifelong Learning In Prevention of Suicide In Europe (ELLIPSE)-project is co-funded by the European Union’s Programme Erasmus+ (Project ID: 2019-1-SE01-KA203-060571). The EU Commission’s support for this project does not mean that the Com
Encephalopathy caused by disulfiram
Authors: Sant’Angelo R. , Piretti I. 
Published: February 2022

IntroductionDisulfiram is an alcohol detox drug that has been approved by the FDA for over 50 years. Among the various side effects that can cause there is encephalopathy. Its incidence is currently unknown, according to some authors it is estimated between 1 and 20%.ObjectivesIn this article we report the case of a 48-year-old woman diagnosed with borderline personality disorder and alcohol use disorder, presenting with encephalopathy.MethodsWe discuss about our diagnostic and therapeutic approach.ResultsFortunately, the rapid identification of this rare condition led to a favorable outcome in our patient.ConclusionsEarly detection of any acute change in mental state, especially in early stage of therapy, is important. Cessation of disulfiram is recommended in case of suspicion about disulfiram encephalopathy. This case underscores the importance of awareness of this serious complication during disulfiram treatment. If suspected early, appropriate diagnosis and treatment can prevent rapid progression.DisclosureNo significant relationships.
Climate factors associated with help seeking of patient suffering from suicidal stress: The case of rainy days
Authors: Hernández-Calle D. , Bravo-Ortiz M.F. 
Published: February 2022

IntroductionSuicidal phenomena help seeking depends on a broad array of factors, which include climatic variables. Our aim was to analyse the effect of precipitation with help seeking in patients suffering from suicidal behaviourObjectivesOur aim was to analyse the effect of precipitation with help seeking in patients suffering from suicidal behaviourMethodsDaily urgency visits from suicidal phenomena (including suicide attempt and ideation) were extracted from electronic medical records of Hospital Universitario La Paz from 1st January 2019 to 31st December 2019. Precipitation data (measured as accumulated litres per square meter) was obtained from a local climate station. Spearman correlation was estimatedResultsThe Spearman correlation coefficient was 0.04(p = 0.48)ConclusionsPrecipitation did not influence help seeking for patients affected by suicidal phenomenaDisclosureNo significant relationships.
Neuroendocrine factors - predictors of the formation of alcohol dependence and human ecology in various ethnic populations, new approaches to therapy
Authors: Shushpanova T. , Mandel A. , Bokhan N. , Novozheeva T. 
Published: February 2022

IntroductionIntegrated clinical and biological approaches in the study of disorders caused by alcohol consumption in people of different ethnic groups, are important for determining effective treatment strategies.ObjectivesTo study the clinical and dynamic features and the role of neuroendocrine factors of the formation and course of alcohol dependence in individuals of Tuvan ethnicity.Methods68 Russian alcoholics and 67 Tuvans alcoholics only men and 20 healthy male were monitored. Clinical assessment of the condition of patients was carried out with the traditional clinical description. Enzyme-linked immunosorbent assay kits were used to determine serum hormone levels in patients and volunteers.ResultsThe systematic consumption of alcoholic beverages develops among Tuvans in adulthood, in contrast to Russian men who begin to drink systematically young. Alcohol dependence in people of Tuvan nationality are formed several years later than in Russians: a symptom of loss of quantitative control over use was detected in Tuvans at 36.9±9.9 years, in Russian patients at 29,8±7.5 years; the formation of withdrawal syndrome in Tuvans occurs at the age of 37.7±8.4 years, unlike Russians, in whom the withdrawal syndrome develops on average at the age of 29.6±6.0 years. The index of the ratio cortisol/progesterone in the blood of examined Russian alcoholics is almost twice as high as the index of examined healthy donors; in patients of Tuvan ethnicity, index is almost five times higher.ConclusionsAlcohol dependence among representatives of the Tuvan ethnic group indicates a greater vulnerability to the effects of alcohol.DisclosureNo significant relationships.
A populational review of the amyloid precursor protein gene mutations relevant to alzheimer’s disease
Authors: Balmus I.M. , Ciobica A. , Gorgan L.D. 
Published: February 2022

IntroductionThe genetic component of Alzheimer’s disease was previously studied and more than sixty amyloid precursor protein (APP) gene mutations were identified. However, the populational aspects of this component were scarcely discussed despite that many of the reports mentioned the demographic ancestry of the carriers or probands.ObjectivesIn this short study, we aimed to review the APP gene mutations relevant to Alzheimer’s disease from a Populational Genetics point of view by evaluating the current literature for the demographic description of the carriers or families in which the mutations were identified.MethodsIn this regard, multiple genetic studies on the APP gene mutations relevant to Alzheimer’s disease were reviewed and the incidence of the mutations was analyzed considering the ancestry of the patients.ResultsWe found many possible scenarios regarding the incidence of the APP gene mutations in Alzheimer’s disease patients and general population. On the one hand, we could identify several mutations which were present in more than one population (eg. V615M, V717I, V717L) and on the other hand, some mutations could be observed in certain populations (eg. E693delta, the Osaka mutation, which was until now observed in Japanese patients, while E693G was found in a Swedish family). One particular case is that of the isolated populations (eg. the Icelandic population in which an APP mutation protecting against Alzheimer’s disease is more frequent in the general population as compared to the patients).ConclusionsWe were able to identify several mutations which were characteristic to many populations, but also some population-specific features regarding the APP genotypes.DisclosureNo significant relationships.
Training in women mental health: Challenges and future perspectives
Authors: Wieck A. 
Published: February 2022

Mental disorders linked with the menstrual cycle, childbirth and the menopause are unique to women and have their specific requirements for identification, assessment, treatment and service provision as well as appropriately trained staff. Mental disorders that are linked to domestic violence, sexual abuse or victimisation and affect more women than men, also have their own specific requirements. This is increasingly being recognized by policy makers and health care planners. In the case of perinatal mental health some countries have set up specialised inpatient and community services. In the UK this was followed by the development of National competencies for different professional groups and National training programmes. This project and the current clinical training in perinatal mental health for psychiatric trainees will be described. Nationally recognized qualifications are currently being developed. Developments in other areas of women’s mental health appear less advanced. The presentation will discuss current guidelines and opportunities for training that are being offered in the UK and what we can learn from perinatal mental health for further development in these areas.DisclosureNo significant relationships.
Psychopathology and treatment of Prader-Willi syndrome in adulthood: About a clinical case
Authors: Martinez G.M. Ruiz , Dafonte A. Alvarado , Rodriguez L. Soldado 
Published: February 2022

IntroductionPrader-Willi syndrome is a congenital disease caused by a genetic alteration of chromosome 15, described by doctors Prader, Labhart and Willi in 1956. It’s a rare disease (prevalence 2.8/100,000) and it occurs equally in both sexes and in all races. This disorder produces changes in hypothalamic function that can lead to muscle hypotonia, short stature, a compulsion to eat, and a lack of satiety. At the psychopathological level, the clinic is very varied, being mainly important the psychomotor retardation in different degrees and behavioral problems;especially in the behavioral phenotype. Affective and psychotic symptoms are also frequent.ObjectivesPsychopathology and treatment analysis through a clinical case.Methods40-year-old patient undergoing mental health follow-up since adolescence with a diagnosis of paranoid personality disorder. No medical history of interest. He was admitted to the hospitalization unit for serious behavioral alterations in a context of probable paranoid ideation towards the neighborhood. In the psychopathological examination, marked cognitive rigidity, high impulsivity and very low tolerance to frustration stand out, showing a hostile and defiant attitude. Poorly structured paranoid ideation. Presents obsessive-compulsive behaviors (scratching). Hyperphagia and obesity.ResultsPsychometric assessment (Waiss-IV): total IQ 61 (mild mental retardation). Genetics:deletion 15 q11-q13 of chromosome 15), confirms Prader-Willi diagnosis. Remission of behavioral disorders, suspiciousness and heteroaggressive behaviors with treatment with monthly depot paliperidone (150 mg).ConclusionsKnowledge of the clinical and morphological characteristics of this syndrome would allow an early diagnosis and treat its possible complications as soon as possible. Antipsychotic treatment is effective in the management of behavioral and psychotic symptoms.DisclosureNo significant relationships.
Personal restoration and feelings of guilt with victims of forced displacement in the colombian caribbean
Authors: Gonzalez E.P. Ruiz , Guzman M.J. Arcos , Argel M.N. Muñoz , Urzola A. Uribe , Carvajal J.D. Velez 
Published: February 2022

IntroductionForced displacement has been shown as a direct consequence of civil wars and armed confrontations, its effects on the victims are evidenced in the material, physical health and psychosocial effects (Mendoza, 2012; Pavas & Díaz, 2019; Ramos, 2018). It is common to identify in victims the presence of a post-offense emotional discomfort, which is recommended to work as a way of forgiveness for the achievement of personal restoration (Prieto & Echegoyen, 2015).ObjectivesFor this reason, the results of the study are presented, which has aimed to analyze the relationship between personal restoration and feelings of guilt with victims of forced displacement in the Colombian Caribbean.MethodsA correlational study has been carried out with a sample of 40 (n = 40) subjects of which 52.5% are men and 47.5% women, the mean age is 57.52 (σ = 13.591), all with a history of forced displacement; to the data collection has been used the CAPER instrument of Rosales, Rivera and Garcia (2017) (α = .592).ResultsThere is a positive bilateral correlation between the variables studied (r = .000; p = .829), the greater the personal restoration, the greater the sense of guilt is also manifested.ConclusionsFor therapeutic work in personal restoration with victims of forced displacement, it is important to also include the feeling of guilt, which is presented as post-offense emotional distress.DisclosureNo significant relationships.
Engineering psychiatric education 2.0 in post-pandemic europe
Authors: De Picker L. 
Published: February 2022

In the world of medical education, there is generally a lot of emphasis on following procedure and tradition, and a reluctance to challenge the norm. It takes insight and courage to question traditional approaches and paradigms: why are psychiatric training programs done the way that they are? Reverse engineering involves taking something apart and analysing its workings to figure out how it does what it does and how it can be improved. In education, reverse engineering implies one determines learning outcomes upfront and then works back from them. Applied to postgraduate psychiatric training, it requires us to determine the basic principles or core concepts resulting in the successful formation of a well-rounded psychiatrist. In times of crisis there usually is more leeway to challenge the status-quo – hence the saying “never waste a good crisis”. Indeed, if the COVID-19 crisis has taught us anything, it is that education should be meeting learners where their attention is at, and that any healthcare organisation can be transformed within weeks when given the right incentives. In this workshop, Dr. De Picker will reflect on how post-COVID European psychiatric training can reinvent itself to address long-standing concerns and unmet needs. Innovative approaches will be needed to start shaping the psychiatrists of the future.DisclosureNo significant relationships.
Adolescents with cleft lip and palate (CLP): Stressful events and coping
Authors: Pacheco P. , Pacheco M. , Molini-Avejonas D. , Mota-Loss A. 
Published: February 2022

IntroductionIndividuals with CLP may present communication disorders, velopharyngeal dysfunction, dento-occlusal changes and hearing losses. Adolescents with CLP usually show greater impairment of communication. Such characteristics combined with the malformed face can impact psychosocial functioning and increase the risk of psychological difficulties. Life-stressing experiences from CLP to life events typical of adolescence, may threaten the well-being of the adolescent, and are linked to mental health and behavioral problems.ObjectivesTo verify the coping of adolescents with CLP through a descriptive cross - sectional study.MethodsFifteen adolescents with CLP participated in the study. To evaluate them it was used the Coping scale (Lees, 2007), for the verification of coping in the families proposed by Motivational Theory of Coping. The analysis of the coping of adolescents with CLP considered two adverse contexts, namely “birth with fissure” and “have your secret told by a friend ”.ResultsIn relation to the evaluation of the psychological needs of relationship, competence and autonomy faced the “birth with fissure” indicates that teens with fissures do not perceive this stressor as a threat to their basic psychological needs.ConclusionsThe adolescents with CLP who participated in the study feel more interested (perception of the challenge) in dealing with the stressor relative to the fissure than in dealing with the betrayal of a friend, who reveals a secret of his to other people.DisclosureNo significant relationships.
Migration: A risk factor for psychosis?
Authors: Spaho E. , Alikaj V. , Dashi E. , Skendi V. 
Published: February 2022

IntroductionEmigration is a complex process of social changing through which an individual moves from a certain cultural environment/context to another, aiming to achieve persistent or long-term residency, causing distress. There is sustainable evidence that incidence of all forms of psychosis is higher in migrants.ObjectivesThis study aims to gather data of other research conducted in the field according to emigration as a risk factor for development of different psychosis.MethodsScientific articles searched in MEDLINE, regarding the incidence of mental disorders in different emigrant populations, for the period 1995 - 2015.ResultsThe average relative risk of schizophrenia and of other psychosis occurrence among first generation emigrants was 2.7 (95% confidence interval [CI]=2.3-3.2). Statistical analysis performed among studies of first and second generation of emigrants, and among studies which don’t make difference between generations, results in a relative risk of 2.9 (95% CI=2.5-3.4) of mental illness.ConclusionsThe data presented in this study emphasize the impact of migration on central symptoms of schizophrenia. Emigration process, cultural and social adaptation, play an important role on the individual mental health.DisclosureNo significant relationships.