bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effective dose of propofol combined with a low-dose esketamine for gastroscopy in elderly patients: A dose finding study using dixon’s up-and-down method
Authors: Zheng Yuling , Xu Yafei , Huang Bixin , Mai Ying , Zhang Yiwen , Zhang Zhongqi 
Published: September 2022

Objective: This study aimed to determine the optimal dose of propofol combined with esketamine to inhibit the response to gastroscope insertion in elderly patients.Methods: This is a prospective, non-controlled, non-randomized, single-center study. Elderly patients aged 65–80 years were enrolled in the study with the American society of anesthesiologists (ASA) physical status I or II undergoing elective gastroscopy. All patients were administered propofol after an intravenous esketamine at the dosage of 0.3 mg/kg 30 s, the subsequent dose of propofol was determined by the response of the previous patient to gastroscope insertion (choking, body movement, etc.) using Dixon’s up-and-down method. The initial dose of propofol administered to the first elderly patient was 3.0 mg/kg, and the standard ratio of propofol dose in adjacent patients was 0.9. At least six crossover points were obtained before the conclusion of the study. By using Probit analysis the median effective dose (ED50), 95% effective dose (ED95), and the corresponding 95% confidence interval (CI) for propofol were determined.Results: The study continued until we obtained seven crossover points and 32 elderly patients (17 males and 15 females) were collected. The ED50 of propofol combined with esketamine inhibiting response to gastroscope insertion in elderly patients were found to be 1.479 mg/kg (95% CI 1.331–1.592 mg/kg), and ED95 was found to be 1.738 mg/kg (95% CI 1.614–2.487 mg/kg).Conclusion: According to the present study, propofol combined with 0.3 mg/kg esketamine is safe and effective for elderly patients undergoing gastroscopy. The ED50 and ED95 doses of propofol inhibiting response to gastroscope insertion in elderly patients when combined with 0.3 mg/kg esketamine were 1.479 and 1.738 mg/kg, respectively, without apparent adverse effects.
To be assertive or not to be assertive: That is the question! Students' reactions to sexual harassment in academia
Authors: Cabras Cristina , Sechi Cristina , Agus Mirian , Cois Ester , Casula Clementina , Raffo Luigi , Mosca Oriana 
Published: September 2022

IntroductionIn the literature, no integrated definition of sexual harassment (SH) occurs but there is clear unanimity about SH being offensive, humiliating, and intimidating behavior. Within academic settings, SH has severe negative effects on students' physical or emotional wellbeing as well as on their ability to succeed academically.MethodsThe aim of this study was to investigate the relationship between sex, gender roles, and the ways to manage SH (assertive and nonassertive reactions) in university students. It was hypothesized that female students would report more nonassertive reactions compared to male students. In addition, following the Bem theory on gender roles and using the self-report tool by the same author, it is hypothesized that female and male students, who are classified as feminine, will report more nonassertive responses, whereas male and female students, who are classified as masculine, will report more assertive responses. Our hypothesis was tested with a sample of 1,415 university students (593 men, 41.9%, and 822 women, 58.1%) who completed a questionnaire approved by the local ethical review board for research from the end of January 2019 to the first half of February 2019.ResultsContrary to our hypothesis, results showed that women react more than men in both assertive and nonassertive modalities. In addition, our results confirmed the main effect of both sex and gender roles on students' assertive and nonassertive reactions to SH in academia.ConclusionEducational programs about SH may prove useful in preventing its occurrence. Gender equality plans in academia can improve a nonsexist and safe environment for students. It is urgent to improve transparency and accountability of policies on the management of SH: academic institutions need to formulate a procedure to facilitate SH reporting, considering the sensitive balance of confidentiality and transparency issues. Support for the victims (social services, healthcare, legal representation, and advice concerning career/professional development) must be included.
Childhood maltreatment increases the suicidal risk in Chinese schizophrenia patients
Authors: Cheng Peng , Ju Peijun , Xia Qingrong , Chen Yuanyuan , Li Jingwei , Gao Jianliang , Zhang Loufeng , Yan Fanfan , Cheng Xialong , Pei Wenzhi , Chen Long , Zhu Cuizhen , Zhang Xulai 
Published: September 2022

ObjectivesChildhood trauma might be a modifiable risk factor among adults with serious mental illness. However, the correlation of child trauma and suicide is unclear, which were cited most frequently as the biggest challenge to schizophrenia (SCZ) patients in China. We aim to study relationships between child trauma and suicide in SCZ patients of different disease stages.MethodsNinety-one participants were included and divided into two groups, namely, first-episode group (n = 46), relapsed group (n = 45). The Positive and Negative Syndrome Scale was used to evaluate the severity of psychotic symptoms. The Beck's Suicide Intent Scale and The Nurses' Global Assessment of Suicide Risk were conducted by patient self-report to assess suicide symptom. The childhood trauma questionnaire was used to estimate severity of traumatic stress experienced during childhood.ResultsChildhood trauma and different dimensions of suicide were significantly higher in the relapsed group than first-episode group (P &lt; 0.01, respectively). BMI has a significant positive relationship with recent psychosocial stress (β = 0.473, t = 3.521, P &lt; 0.001) in first-episode group. As in relapsed group, BMI has a positive effect between severe mental illness and suicide ideation (β = 0.672, t = 5.949, P &lt; 0.001; β = 0.909, t = 2.463, P &lt; 0.001), Furthermore, emotional neglect presented positively related to the suicide risk and proneness to suicidal behavior (β = 0.618, t = 5.518, P &lt; 0.001; β = 0.809, t = 5.356, P &lt; 0.001).ConclusionRelapsed group of patients had significantly more severe childhood trauma, recent psychosocial stress, suicidal risk and proneness to suicidal behavior. BMI and emotional neglect are unique predictors for different dimensions of suicide.
COVID-19-related impact on mental health and career uncertainty in student-athletes—Data from a cohort of 7,025 athletes in an elite sport high school system in Sweden
Authors: Håkansson Anders , Moesch Karin , Kenttä Göran 
Published: September 2022

ObjectivesMental health consequences and behavior change has been described in elite athletes following the vast impact of the COVID-19 pandemic on the world of sports. However, most study samples have been of limited size, and few studies have assessed student-athletes. This study aimed to analyze perceived mental health impact, measured as clinical degree of depression and anxiety, worry about one's sport and about one's career, and behavioral change with respect to video gaming behavior, in high-school athletes in Sweden.MethodsData on anxiety and depression as well as on perceived behavioral changes during COVID-19 were collected from students at sports high schools in Sweden (N = 7,025) in February 2021, during the ongoing COVID-19 pandemic.ResultsSixteen and 14% met criteria of moderate/severe depression and anxiety, respectively. Many respondents reported feeling mentally worse during the pandemic (66%), and were worried about the future of their sport (45%) or about their own future in sports (45%). Increased gaming behavior during COVID-19 was reported by 29%. All mental health variables were significantly more common in women, except increased gaming (more common in men). Being worried about one's career was less common in winter sports, more common in team sports and more common in older student-athletes, and associated with both depression and anxiety in regression analyses.DiscussionSelf-reported mental health impact of COVID-19 is substantial in student-athletes, and even more so in women and in team sports. The lower impact in winter athletes suggests a moderating effect of the seasons in which the COVID-19 outbreak occurred.
The diagnostic value of non-invasive methods for diagnosing bladder outlet obstruction in men with lower urinary tract symptoms: A meta-analysis
Authors: Cheng Yu , Li Taicheng , Wu Xiaoyu , Ling Qin , Rao Ke , Yuan Xiaoyi , Chen Zhong , Du Guanghui , Xu Shengfei 
Published: September 2022

PurposeWe conducted the first meta-analysis to determine the diagnostic value of non-invasive methods for diagnosing bladder outlet obstruction (BOO) in men with lower urinary tract symptoms (LUTS).MethodsWe searched a range of databases for relevant publications up to June 2022, including PubMed, Embase, Web of Science, and the Cochrane Library. Retrieved studies were then reviewed for eligibility and data were extracted. The risk of bias (RoB) was assessed using the QUADAS-2 tool. We then performed a formal meta-analysis to evaluate the accuracy of various non-invasive methods for diagnosing BOO in men.ResultsWe identified 51 eligible studies including 7,897 patients for meta-analysis. The majority of the studies had a low overall RoB. Detrusor wall thickness (DWT) (pooled sensitivity (SSY): 71%; specificity (SPY): 88%; diagnostic odds ratio (DOR): 17.15; area under curve (AUC) 0.87) and the penile cuff test (PCT) (pooled SSY: 87%; SPY: 78%; DOR: 23.54; AUC: 0.88) showed high accuracy for diagnosing BOO. Furthermore, data suggested that DWT had the highest pooled SPY (0.89), DOR (32.58), and AUC (0.90), when using 2 mm as the cut-off.ConclusionOf the non-invasive tests tested, DWT and PCT had the highest levels of diagnostic accuracy for diagnosing BOO in men with LUTS. DWT, with a 2 mm cut-off, had the highest level of accuracy. These two methods represent good options as non-invasive tools for evaluating BOO in males.
Diﬀerent response criteria to cardiac resynchronization therapy in patients with congestive heart failure
Authors: Soldatova A. M. , Kuznetsov V. A. , Malishevskaya D. S. , Malishevskii L. M. , Enina T. N. , Gorbatenko E. A. 
Published: September 2022

Aim. To investigate the agreement among diﬀerent response criteria to cardiac resynchronization therapy (CRT) and long-term mortality in patients with congestive heart failure (CHF).Methods. The study enrolled 141 patients (men 77.3%; women 22.7%) with CHF (65.2% ischemic and 34.8% non-ischemic etiology). Mean age was 58.6 [53.0;66.0] years. All patients had NYHA II-IV, left ventricular ejection fraction (LVEF) ≤35%; QRS ≥130 мs and/or left bundle branch block. Mean follow-up period was 45.0±34.2 months. Response to CRT was deﬁned according to dynamics of NYHA functional class, LVEF, and left-ventricular end-systolic volume (LVESV).Results. Moderate agreement was found among LVEF and LVESV (Cohen’s k coeﬃcient 0.591±0.068) while we did not ﬁnd the agreement among echocardiographic criteria and NYHA. Long-term mortality had moderate negative correlation with LVESV (r=-0.486; pConclusion. Agreement between diﬀerent criteria to deﬁne response to CRT is poor. The strongest correlation with long-term mortality was found for LVESV. This inconsistency among diﬀerent response criteria severely limits the ability to generalize results over multiple CRT studies.
Aprendizajes significativos en la formación de terapeutas familiares de la Universidad Católica Luis Amigó
Authors: Herrera Rivera Ovidio , Bedoya Cardona Ledy Maryory 
Published: September 2022

Formar-se cómo terapeuta familiar induce a pensar en procesos de intervención con las familias, pero también consigo mismo. En este sentido, el objetivo del estudio se centró en identificar aprendizajes significativos desde el ser, hacer y saber de terapeutas en formación, durante el curso de entrenamiento, adscrito a la Especialización en Terapia Familiar de la Universidad Católica Luis Amigó. En sintonía con estos intereses, la investigación fue de corte cualitativo, al habilitar contextos interpretativos de experiencias vinculadas al proceso formativo; al respecto, la organización, sistematización y análisis de información estuvo mediada por el método de análisis de contenido (AC); metodología que busca trascender lo subjetivo a procesos de objetivación, mediante el uso de técnicas e instrumentos, como la entrevista a profundidad. Acorde con los resultados, se encontró que los aprendizajes de los estudiantes están estrechamente vinculados con el ser, hacer y saber, como meta-aprendizajes para la vida. El estudio concluye que el proceso de formación de terapeutas familiares induce ineludiblemente a una perspectiva holística de la realidad personal, familiar y social, que conjuga aprendizajes significativos, vistos como puntos de partida para confrontar y evaluar procesos de transformación, mediatizados por la autoreflexividad y la confrontación personal y familiar, que van más allá de las teorías formativas.

Palabras clave: Aprendizaje, aprendizajes significativos, formación en terapia familiar, terapia familiar.
تأثير وحدات تعليمية وفقا للأنشطة الرياضية الصفية و اللاصفية في بعض عناصر اللياقة البدنية والسلوك العدواني لدى طلاب المرحلة المتوسطة
Authors: A.M.D. Ali Khawam Khatib  
Published: September 2022

هدف البحث الى عداد انشطة رياضية صفية (منهجية) ولا صفيه كعمل بطولات بين الصفوف ومعرفه تأثير النشاط الرياضي في السلوك العدواني لدى عينة من طلاب المرحلة المتوسطة ومعرفه تأثير النشاط الرياضي الصفي واللاصفي في بعض عناصر اللياقة البدنية لدى طلاب المرحلة المتوسطة وتم اختيار المنهج التجريبي (ذو المجموعة الواحدة) كونه اكثر ملائمة مع مشكلة البحث , اذ تم اختيار العينة من (86) طالب من الصف الثاني متوسط في متوسطة العدالة في تربية الكرخ الثالثة وقام الباحث باجراء الاختبارات القبلية وتم تطبيق مقياس السلوك العدواني واختبارات اللياقة البدنية على عينة البحث وبعد مرور ثمان اسابيع تم اجراء الاختبارات البعدية وتمت معالجة نتائج البيانات احصائيا وبعد العرض والمناقشة تم التوصل الى نتائج ان درس التربية الرياضية له تأثير مباشر في خفض السلوك العدواني لدى طلاب الصف الثاني المتوسط .كما ان درس التربية الرياضية له تأثير مباشر في بعض عناصر اللياقة البدنية كماو ظهرت فروق معنوية ذات دلالة احصائية في نسبة السلوك العدواني ولصالح الاختبار البعدي . و ظهرت فروق معنوية ذات دلاله إحصائية في اختبارات اللياقة البدنية ولصالح الاختبارات البعدية .
تأثير استخدام وسيله مساعدة مقترحة لتطوير تعلم مهارة التصويب بالقفز بكرة السلة لدى طلاب المرحلة الاعدادية
Authors: Nabhan hameed Ahmad  , Asseel  dawood Salman  
Published: September 2022

هدف البحث اعداد وسيلة مقترحة لتطوير مهارة التصويب بالقفز بكرة السلة لدى طلاب المرحلة الاعدادية ،وكان الباحثون ملتزمون باتباع اجراءات البحث العلمية من خلال التجربة الاستطلاعية للتأكد من صلاحية الوسيلة وهي (وهي عبارة عن لوح خشبي بعرض 2م وارتفاع 2م مثبته من الاسفل بقاعدة خشبية , ويمكن نقلها من مكان الى أخر , وطريقة استخدامها تتم بوقوف المتعلم بجانب اللوح الخشبي اثناء التهديف وعند حدوث خطأ في الأداء سوف يلامس كوع ذراع المتعلم اللوحة الخشبية وبذلك يعمل المتعلم على تعديل حركة الذراع بحيث لا يخرج كوع الذراع الى الجانب وبذلك يتم تعديل المسار الحركي في التكرار الذي يليه من خلال توفير تغذية راجعة أنية) ،وقد تم تنفيذ البحث بالمنهج التجريبي باسلوب الضبط المحكم على عينة تمثل 20طالب للمرحلة الرابعة في اعدادية المغيرة بن شعبة للبنين نظرا لتوفر الظروف الامكانيات لتحقق اهداف البحث ،وبعد تطبيق المنهج التعليمي الذي استغرق 4 اسابيع بمعدل وحدتين في الاسبوع وحسب الجدول الدراسي، تم معالجه نتائج القياسات القبلية والبعدية للمجموعتين الضابطة والتجريبية اذ تم التواصل الى استنتاجات اهمها هو التأثيرالايجابي للوسيلة التي اقترحها الباحثون في تطوير التعلم لمهارة التصويب بالقفز ،كما انها وفرت عنصر التشويق لدى عينة البحث فقد وفرت تغذية راجعة انية عند الاداء وكانت اهم التوصيات هي الاستفادة من الوسيلة المساعدة عند تعلم وتطوير مهارة التصويب بالقفز بكرة السلة وضرورة تطبيق ابحاث اخرى باستخدام وسائل مساعدة والتعرف عل تأثيرها بكرة السلة وبألعاب اخرى .
Characterization of Pyrenophora tritici-repentis (tan spot of wheat) races in Kazakhstan
Authors: KUMARBAYEVA Madina , KOKHMETOVA Alma , KOVALENKO Nadezhda , ATISHOVA Makpal , KEISHILOV Zhenis , AITYMBETOVA Klara 
Published: September 2022

Tan spot, caused by Pyrenophora tritici-repentis, is an economically important foliar disease of wheat in Kazakhstan. Population structure of the pathogen changes every year due to climate change. This study aimed to characterize the race structure of P. tritici-repentis isolates recovered from wheat in south and north Kazakhstan, and identify tan spot resistance in host genotypes based on disease phenotypes and molecular screening. Virulence profiles were determined within 40 isolates of the pathogen from wheat crops during the 2020 growing season. Seven races, (1, 3, 4, 5, 6, 7 and 8) were identified. A collection of 80 wheat accessions, including promising lines and cultivars from Kazakhstan and Russia, were evaluated for their reactions to races 1 and 5 of the pathogen, and to Ptr ToxA and Ptr ToxB, using greenhouse assessments and molecular markers diagnostic for the Tsn1 and Tsc2 genes. From a practical viewpoint, 18 wheat genotypes were insensitive to the two races and the two Ptr toxins. This resistant germplasm can be used in breeding programmes aiming to develop wheat varieties resistant to P. tritici-repentis.
MODELS OF REMOTE CONTROL OF THE MOVEMENT OF AN UNMANNED VESSEL
Authors: Болнокин В.Е. , Каперко А.Ф. , Сорокин С.А. , Саксонов Е.А. 
Published: September 2022

Разработаны и исследованы алгоритмы дистанционного управления движением судна, использующие данные системы глобального позиционирования, и обеспечивающие достижение заданной цели с требуемой точностью. Алгоритмы учитывают случайные воздействия на судно внешних факторов, определяющих отклонение судна от назначенного курса.
Algorithms for remote control of the vessel's movement using the data of the global positioning system and ensuring the achievement of a given goal with the required accuracy have been developed and investigated. The algorithms take into account the accidental effects on the vessel of external factors that determine the deviation of the vessel from the designated course.
IMPLEMENTASI TINDAKAN ASERTIF PADA KLIEN SKIZOFRENIA DENGAN MASALAH PERILAKU KEKERASAN UNTUK MENGEKSPRESIKAN MARAH
Authors: Nabilah Putri , Kusumawaty Ira , Martini Sri , Yunike Yunike 
Published: September 2022

Latar Belakang: Perilaku kekerasan merupakan suatu bentuk ekspresi kemarahan yang tidak sesuai, ditandai dengan tindakan yang dapat membahayakan atau mencederai diri sendiri, orang lain maupun lingkungan. Tindakan asertif adalah tindakan mengungkapkan perasaan secara langsung kepada orang lain yang dilakukan untuk mengekspresikan marah, meminta, dan menolak dengan baik dan sopan tanpa merugikan diri sendiri, orang lain maupun lingkungan. Penting bagi klien perilaku kekerasan untuk dapat melakukan tindakan asertif. Tujuan: Memperoleh gambaran kemampuan klien skizofrenia dalam mengimplementasikan tindakan asertif dalam mengekspresikan kemarahannya. Metode: Jenis penelitian yang digunakan adalah deskriptif dalam bentuk studi kasus menggunakan pendekatan proses keperawatan yang meliputi pengkajian, diagnosa keperawatan, intervensi keperawatan, implementasi keperawatan, evaluasi dan tindak lanjut. Penentuan subyek pada penelitian ini menggunakan teknik pengambilan sampel purposive sampling, dengan melibatkan klien skizofrenia yang sedang dirawat di klinik rawat inap bagi orang dengan gangguan jiwa. Hasil: Implementasi tindakan asertif sebagai intervensi dalam mengekspresikan marah dapat dilaksanakan secara efektif pada kedua klien, namun menjadi kurang efektif yang terjadi pada satu klien lainnya. Perbedaan kondisi dan karakteristik klien turut mempengaruhi keberhasilan implementasi tindakan asertif. Dapat disimpulkan bahwa tindakan asertif dapat menjadi intervensi dalam mengekspresikan marah pada klien skizofrenia dengan masalah perilaku kekerasan. Saran: Disarankan agar keterlibatan keluarga untuk dapat dioptimalkan agar tindakan asertif dapat dilanjutkan di rumah sehingga mengurangi perilaku kekerasan klien. Koordinasi antara pihak pemberi layanan keperawatan bersama keluarga menjadi salah satu kunci keberhasilan proses perawatan terhadap orang dengan gangguan jiwa. Kata Kunci: Skizofrenia, Mengekspresikan Marah, Tindakan Asertif
PERBEDAAN PEMERIKSAAN DARAH SEGERA DAN DITUNDA SELAMA 6 JAM PADA SUHU 4-8OC TERHADAP KADAR HEMOGLOBIN DENGAN HEMATOLOGY ANALYZER
Authors: Saputra Oka Dwi , Aristoteles Aristoteles 
Published: September 2022

Latar Belakang: Pemeriksaan hematologi adalah pemeriksaan yang dilakukan untuk mengetahui keadaan darah dan komponen-komponen di dalam darah. Darah terdiri dari eritrosit, leukosit, trombosit, serta cairan yang berwarna kekuningan disebut dengan plasma. Hemoglobin merupakan suatu protein tetramerik eritrosit yang mengikat molekul bukan protein yaitu senyawa porfirin besi yang disebut dengan heme. Hemoglobin mempunyai peran penting dalam sistem pengangkutan pada tubuh manusia yang utama yaitu mengangkut oksigen ke seluruh jaringan dan yang kedua yaitu memindahkan karbondioksida dari jaringan perifer ke organ respirasi. Kadar hemoglobin dapat diukur dengan menggunakan penghitung sel otomatis (hematology analyzer) yang secara langsung mengukur kadar hemoglobin Tujuan: Diketahui perbedaan pemeriksaan darah segera dan ditunda selama 6 jam pada suhu 4-8oC terhadap kadar hemoglobin dengan Hematology Analyzery. Metode: Jenis penelitian yang dilakukan dalam penelitian ini adalah cross sectional. Jumlah sampel yang digunakan dalam penelitian ini sebanyak 30 sampel yang terdiri mahasiswi tingkat 1 dan 4 program studi DIV Teknologi Laboratorium Medis. Penelitian ini dilakukan di Laboratorium Hematologi IKesT MP pada tanggal 01 April 2021. Pemeriksaan kadar hemoglobin menggunakan alat Hematology analyzer. Hasil: Pada penelitian didapatkan kadar hemoglobin yang segera diperiksa paling rendah sebesar 10,3 g/dL dan yang paling tinggi sebesar 14,4 g/dL, sedangkan kadar hemoglobin yang ditunda selama 6 jam pada suhu 4-8oC didapatkan kadar hemoglobin paling rendah sebesar 9,9 g/dL dan yang paling tinggi sebesar 14,1 g/dL. Saran: Diharapkan dari hasil penelitian ini, bagi peneliti selanjutnya dapat dijadikan sebagai bahan perbandingan dengan penelitian sebelumnya, penelitian ini dapat juga dilanjutkan dengan pemeriksaan hemoglobin dengan suhu yang berbeda dan dapat dijadikan sebagai referensi untuk penelitian selanjutnya dengan parameter hematologi yang berbeda. Kata Kunci: Hemoglobin, Hematology Analyzer, Suhu, Penyimpanan