bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pregnancy associated atypical hemolytic uremic syndrome presenting with preeclampsia with HELLP syndrome and following treatment with Eculizumab
Authors: Gunawan Fery , Mangler Mandy , Sanders Cindy , Leonardo Trisha Ardine , Cindy Yosefina 
Published: September 2022

Abstract

Objectives
Pregnancy associated atypical hemolytic uremic syndrome (p-aHUS) is a rare condition of thrombotic microangiopathy (TMA) which causes an increase of fetal and maternal morbidity and mortality. It presents typically with a triad of microangiopathic hemolytic anemia (MAHA), thrombocytopenia and acute progressive renal failure. Differential diagnoses of HELLP (Hemolysis, Elevated Liver enzymes, and Low Platelets) syndrome, preeclampsia, thrombotic thrombocytopenic purpura (TTP), and disseminated intravascular coagulation (DIC) syndrome must be considered. In the following case report, presented is a 32-year-old, 38 weeks pregnant Caucasian woman admitted to Eberswalde Hospital with signs of preeclampsia and HELLP Syndrome. Caesarean Section was performed due to HELLP syndrome and fetal distress. Acute renal failure occurs shortly after a successful delivery. After a diagnosis of p-aHUS is established, the patient was given Eculizumab, which yielded significant improvements.

Case presentation
A 32-year-old, 38 week pregnant Caucasian woman was admitted to Eberswalde Hospital with upper right abdominal pain. After a laboratory examination, a diagnosis of HELLP syndrome was established and a Caesarean Section was performed. The follow-up examination revealed deterioration of clinical signs with the patient experiencing dyspnea, oliguria, and oedema, as well as aggravation of laboratory values, ranging from severe thrombocytopenia, hemolytic anemia, liver injury, and acute kidney injury. After excluding other possible causes of TMA, a diagnosis of p-aHUS was established and a treatment with Eculizumab was administered. Clinical and laboratory signs of hemolysis and kidney functions were found to improve gradually after two administrations of Eculizumab. The patient was discharged after 20 days of hospitalization with significantly improved condition and hematological values.

Conclusions
A successful treatment of p-aHUS requires a comprehensive assessment and a prompt diagnosis, which can be confounded by multiple similar differential diagnoses. Treatment with Eculizumab was found to significantly improve the outcome of the patient, but more studies are required to decide on a standardized regiment for p-aHUS.
Regenerable bacterial killing–releasing ultrathin smart hydrogel surfaces modified with zwitterionic polymer brushes
Authors: Xiao Shengwei , Zhao Yuyu , Jin Shuqi , He Zhicai , Duan Gaigai , Gu Haining , Xu Hongshun , Cao Xingyu , Ma Chunxin , Wu Jun 
Published: September 2022

Abstract
Building long-lasting antimicrobial and clean surfaces is one of the most effective strategies to inhibit bacterial infection, but obtaining an ideal smart surface with highly efficient, controllable, and regenerative properties still encounters many challenges. Herein, we fabricate an ultrathin brush–hydrogel hybrid coating (PSBMA-P(HEAA-co-METAC)) by integrating antifouling polyzwitterionic (PSBMA) brushes and antimicrobial polycationic (P(HEAA-co-METAC)) hydrogels. The smart bacterial killing–releasing properties can be achieved independently by the opposite volume and conformation changes between the swelling (shrinking) of P(HEAA-co-METAC) hydrogel layer and the shrinking (swelling) of PSBMA brushes. The friction test reveals that both METAC and SBMA components support great lubrication. By tuning the initial organosilane (BrTMOS:KH570) ratios, the prepared PSBMA-P(HEAA-co-METAC) coating exhibits different antibacterial abilities from single “capturing–killing” to versatile “capturing–killing–releasing.” Most importantly, 99% of the bacterial-releasing rate can be easily achieved via 0.5 M NaCl treatment. This smart surface not only possesses long-lasting antibacterial performance, only ∼1.09 × 105 cell·cm−2 bacterial residue even after 72 h exposure to bacteria solutions, but also can be regenerated and triggered between water and salt solution multiple times. This work provides a new way to fabricate antibacterial smart hydrogel coatings with bacterial “killing–releasing” functions and shows great potential for biomedical applications.
Preparation and in vitro biocompatibility of PBAT and chitosan composites for novel biodegradable cardiac occluders
Authors: Wang Shanshan , Xing Quansheng 
Published: September 2022

Abstract
The biodegradable composites were prepared by melt blending of chitosan (CS) and poly(butyleneadipate-co-terephthalate) (PBAT). By utilizing Fourier transformed infrared spectroscopy, scanning electron microscopy-energy dispersive spectroscopy, mechanical properties analysis, water contact angle measuring, differential scanning calorimetry, and thermogravimetric analysis, it was demonstrated that the CS of the PBAT-CS10 composite was relatively evenly dispersed in the PBAT matrix, the mechanical properties were significantly improved, the hydrophilicity was increased, the cold crystallization temperature was increased, and a good range of melt working temperature was obtained. The PBAT-CS10 composite was used to fabricate a cardiac occluder by fused deposition modeling of three-dimensional printing, and finite element analysis, and in vitro implantation testing proved the occluder’s mechanical support and sealing function under extreme boundary conditions. In vitro degradation experiments, neutral red uptake cytotoxicity assay, CCK-8 cell proliferation detection, immunofluorescence staining of the cytoskeleton, cell apoptosis detection, and reactive oxygen species assay were all performed on the composite, confirming that it and the occluder made of it could be hydrolyzed under physiological conditions and had no adverse effects on the cell membrane, lysosome membrane, cell proliferation, cell morphology, cell apoptosis, or ROS level, and had good biocompatibility.
Synthesis and crystal structure of 3-(((7-hydroxy-3-(4-hydroxy-3,5-dinitrophenyl)-4-oxo-4H-chromen-8-yl)methyl)(nitroso)amino)propanoic acid, C19H14N4O11
Authors: Chen Hai-Lin , Yao Dong-Mei , Luo Ze-Ping , Wang Yan-Ping , Luo Li-Sheng 
Published: September 2022

Abstract
C19H14N4O11, monoclinic, C2/c (no. 15), a = 17.855(4) Å, b = 18.214(4) Å, c = 14.193(3) Å, β = 124.32(3)°, V = 3812.3(17) Å3, Z = 8, R
gt(F) = 0.0639, wR
ref(F
2) = 0.1897, T = 100.01(10) K.
COCRIAÇÃO DE VALOR NO ENSINO DE PÓS-GRADUAÇÃO
Authors: Da Silva Maicon , Carlos Alves da Silva Luis , Régio Brambilla Flávio 
Published: September 2022

Este artigo, por meio do método observacional aplicado com coleta de dados baseada em cocriação, analisa a geração de valor no ensino superior privado, no ambiente da sala de aula de um programa de pós-graduação stricto sensu de uma Universidade situada no Estado do Rio Grande do Sul, Brasil. Para alcançar os objetivos, a metodologia de pesquisa utilizada foi o estudo de caso único, qualitativo-exploratório, por meio de uma abordagem de orientação etnográfica. Com relação aos resultados obtidos, identificou-se que no ambiente da universidade ocorre a participação, interação, relacionamentos e troca mútua de experiências entre professor e aluno(s). Já, os constructos da pesquisa apontam para evidências de que a cocriação de valor ocorre pela interação entre aluno e professor no ambiente de sala de aula, centrado no valor do saber. Identifica-se também a necessidade de desenvolvimento crítico dos alunos, com base em posturas pouco consistentes no entendimento das práticas pedagógicas, o que alerta para a importância dos processos seletivos e as deficiências na formação educacional de base.
PROPOSIÇÃO DE UM FRAMEWORK PARA A ANÁLISE DA INOVAÇÃO, ECONOMIA CIRCULAR, PERFORMANCE ORGANIZACIONAL E DESENVOLVIMENTO SUSTENTÁVEL
Authors: Andréa Severo Eliana , Cesar Ferro de Guimarães Julio 
Published: September 2022

A inovação é primordial para o desenvolvimento econômico de uma país, entretanto, a economia circular pode ser uma prática ambiental aliada para fomentar a performance organizacional e, consequentemente, o desenvolvimento sustentável, para não comprometer a qualidade de vida das gerações futuras. Neste contexto, a pesquisa tem como objetivo propor um Framework para a análise da inovação, economia circular, performance organizacional e o desenvolvimento sustentável das organizações. O método utilizado foi uma pesquisa qualitativa e exploratória, por meio de uma pesquisa sistemática na base de dados Scopus. Nos achados da pesquisa, contribuições gerenciais e avanços teóricos, o estudo apresentou um Framework que traz informações que podem ser utilizadas pelos gestores de diferentes segmentos de atuação e porte empresarial, que visam fomentar uma inovação que contribua para o desenvolvimento sustentável, fundamentais para a qualidade de vida das pessoas e a manutenção dos recursos naturais. O impacto da pesquisa para o avanço da ciência, proporciona à comunidade acadêmica e aos profissionais das áreas afins, uma melhor compreensão em torno da gestão da inovação e economia circular, assim como a sua contribuição para a performance das organizações e o desenvolvimento sustentável, os quais são primordiais para a manutenção do equilíbrio no planeta.
COMPRAR PARA O MELHOR AMIGO
Authors: Raasch Michele , Henriques de Sousa Júnior João , Coelho Soares João , Soares Santos Weverson , Antunes da Rocha Rudimar 
Published: September 2022

O estudo possui o objetivo de verificar se a forma de relacionamento entre donos de cães e gatos e seus animais possui influência no comportamento de compra. A pesquisa utilizou de metodologia quantitativa via survey, com a participação de 599 respondentes de 25 estados brasileiros. Questões sobre antropomorfismo, autoconceito orientado, e objeto/utilidade foram utilizadas para verificar o tipo de relacionamento entre homem-pet, e sobre esforço e disposição de compra para o comportamento de consumo. Os principais achados deste estudo destacam que o tipo de relacionamento afeta o comportamento de compra dos donos de pets. Frente ao exposto, a pesquisa contribui para o avanço na exploração do comportamento de consumo desse segmento de mercado, possibilitando aos gestores e profissionais de marketing desenvolverem estratégias mais assertivas na influência e estímulo de compra dos donos de animais.
For Entertainment or Escaping From Reality: The Study of University Student Online Video Game Consumption in Malang, East Java Indonesia
Authors: Eskasasnanda I Dewa Putu 
Published: September 2022

This article aims to explain the cause and effect of excessive online video game consumption among university students in Malang City, East Java Indonesia. The informant of this study are university students who fond of playing online video games at late night and early morning in the internet cafe. The research discovers that: 1) living far away from parents, peers, and relatives often make university students feel lonely, this makes them use online video games to drive out their lonesome and boredom. By playing online video games, they can fulfill their social need by interacting with other players,Â and finally, also get fun. 2) The negative side of online video games happens when the students play it excessively due to desire of escaping from real life problems. From this research, it can be revealed that there are similarity patterns among students experiencing online video games excessive consumption. These students are commonly suffering learning difficulties and they are isolated from friends because of taking study majors that are unmatched with their passion and interests. 3) No matter how harmful,Â the games may endanger the studentâ€™s future, all of them feel not too worry. Life in young age and student status they still have made them no need to rush of thinking about their future. These facts are based on their opinion thatÂ becoming an adult and finding a job are still too far away to go
Women and Natural Catastrophe: Managing Risks and Chances for Family Endurance
Authors: Haryanti Nana 
Published: September 2022

Increasing natural degradation has started affecting society particularly women. Conversation links between women and nature is ended up with the fact that women who are mostly suffering from any natural degradations. Natural degradation will lead women to poverty as they have no choices and opportunities to move to satisfactory condition of wealth. In very limited means and infrastructure owned, women take any responsibilities fulfilling family and society needs. In order to avoid possible family shortage, women living in the fishing village work harvesting water hyacinth, an invasive aquatic plant which has negative impact on ecosystem, and gain economic benefits from processing water hyacinth, whilst developing many other domestic strategies for family survival. Â Â
Social Media use among Indonesia’s Generation Z: A Case of University Students in Bandung, West Java
Authors: Gandana Isti , Oktaviandy Rivaldya 
Published: September 2022

Globalization cannot be detached from the processes and results of global interconnections. As one of the most remarkable products of globalization, the internet appears to have become an important part of many peopleâ€™s lives. Among the youth, social media is of particular prominence. This study explores the engagement of a group of Indonesian university students aged 20 to 23â€”also known as the Generation Zâ€”in using social media. The study specifically attempted to inquire into ways in which they perceive social media to impact their lives. Â Questionnaire and individual interviews were used as data collection techniques. Analysis of the data pointed to a high degree of â€˜addictionâ€™ to social media use among students in general.Â The students also revealed both positive and negative impacts of social media use, thus confirming the idea that social media is a double-edged sword that needs to be dealt with carefully and critically.
Implementation of Pre-Admission Caregiver Testing for COVID-19
Authors: He Michael , Peaper David R. , Murray Thomas , Ciaburri Rebecca , Doyle Jeffrey , Loyal Jaspreet 
Published: September 2022

BACKGROUND
Caregivers are often at the bedside of hospitalized children posing an additional risk for coronavirus disease 2019 (COVID-19) transmission. We describe the implementation of caregiver COVID-19 testing before inpatient pediatric admissions and the effect on patient cohorting and bed capacity.

METHODS
We implemented an ordering pathway to facilitate COVID-19 testing of caregivers of patients admitted to the inpatient units from the pediatric emergency department, elective procedural admissions, or direct admissions at a tertiary children’s hospital in the Northeastern United States in August 2021. Testing was expedited by the clinical laboratory, and caregiver results were used to inform cohorting, infection prevention, and bed management decisions.

RESULTS
From August 2021 to January 2022, 2558 caregiver tests were ordered through this pathway, and 83 (3.2%) were positive. Of the positive tests, 72 (86.7%) occurred after December 18, 2021, coinciding with the local Omicron variant wave. Among positives, 67 caregiver or child pairs were identified, and 36 positive caregivers had a COVID-19 negative child leading to use of isolation precautions. Reintroduction of patient cohorting increased overall bed capacity from 74% to 100% of available beds.

CONCLUSIONS
The overall incidence of COVID-19 among caregivers before admission correlated well with rates of COVID-19 positivity among asymptomatic adults in the community during the study period. Implementation of caregiver testing increased bed capacity by reintroducing cohorting of patients and identified patients needing isolation that would have been missed by patient testing alone. More research is necessary to determine the extent that routine caregiver testing mitigates the risk of nosocomial severe acute respiratory syndrome coronavirus 2 transmission.
Relación entre creatividad y rendimiento académico en España y Colombia
Authors: López-Fernández Verónica , Llamas-Salguero Fátima , Sospedra-Baeza María Josefa , Martínez-Álvarez Isabel 
Published: September 2022

Como introducción, este artículo desarrolla que un reto esencial de la educación actual es la capacidad de los alumnos de solucionar de manera creativa las situaciones a las que se enfrentan a lo largo de su vida. En este sentido, el texto busca describir la creatividad y el rendimiento académico en estudiantes de España y Colombia, valorando la relación entre ambas poblaciones en las dos variables, con el fin de poder adaptar la enseñanza al contexto y estudiantes concretos. Como método, se utilizó un diseño cuasi-experimental y descriptivo-Correlacional-comparativo. La muestra estuvo formada por 343 alumnos con una edad media de 13.63 años; el 45.5% de los participantes eran hombres y el 54.5% mujeres. Se empleó la prueba crea para evaluar la creatividad y para el rendimiento se tomó la media obtenida en todas las asignaturas. Frente a los hallazgos se evidencia, a nivel descriptivo, que los estudiantes obtienen resultados medios y medio-bajos en ambas variables y, a nivel correlacional, que existe relación entre ambas variables en la muestra colombiana pero no en la española, pues no se encontraron diferencias entre ambos países en la variable de rendimiento ni creatividad. Finalmente, estos resultados apuntan hacia la importancia del contexto y de estimular la creatividad en las aulas incorporándola en mayor medida en el currículo educativa dándole mayor peso en la evaluación del alumnado. Se sugieren algunas propuestas basadas en las Tecnologías de la Información y Comunicación (tic).
Fatores associados à higiene oral do paciente crítico com COVID-19
Authors: Conceição Luzeni Maria da , Silva Renato Canevari Dutra da , Arantes Ana Paula Felix , Carvalho Marlana Barbosa Carrijo de 
Published: September 2022

Objetivo: O presente estudo teve como objetivo avaliar a higiene oral do paciente crítico com COVID-19 e fatores associados. Métodos: foi realizado um estudo transversal, que consta na avaliação da higiene oral de pacientes internados em UTI com COVID-19 sob uso de ventilação mecânica por meio do Índice de Higiene Oral Simplificado (IHO-S) e do Indicador de Higiene Oral do Paciente Crítico (IHOPC). Resultados: a amostra foi composta por 139 pacientes, sendo 59% do sexo masculino, 44,6% obesos, 93,5% com tubo orotraqueal e 69,8% com alguma comorbidade, dos quais 33,8% apresentaram-se com IHO-S classificado como regular e 12,9% como ruim; e 51,8% com IHOPC precária. Apresentaram avaliação da higiene oral precária por meio do IHOPC os pacientes com maior idade (p=0,049), maior tempo de internação (p=0,018) e com maior tempo de ventilação mecânica (p=0,031). Conclusão: a realização da higiene oral do paciente crítico com COVID-19 necessita ser intensificada nos pacientes internados em UTIs sobretudo os que permanecem longos períodos internados e em ventilação mecânica como forma de evitar intercorrências maiores com paciente já em estados graves.
Dinámica temporal de combustibles forestales y efecto del incendio en Cerro Nambiyugua, Chiapas, México
Authors: Ruiz-Corzo Roldan , Aryal Deb Raj , Venegas-Sandoval Andrea , Jerez-Ramírez Deysi O. , Fernández-Zúñiga Karla S. , Lopez-Cruz Susana del Carmen , López-Herández Juan Carlos , Peña-Alvarez Beatriz , Velázquez-Sanabria Carlos Alberto 
Published: September 2022

Los combustibles forestales son uno de los principales reservorios de carbono, pero también se consideran un factor involucrado en la ocurrencia e intensidad de incendios forestales. El objetivo de este estudio fue analizar la dinámica temporal de almacenamiento y efecto del incendio sobre los combustibles forestales en bosque de pino (Pinus oocarpaSchiede). La medición hojarasca, mantillo y materiales leñosos se realizó de 2010 a 2021 en cuatro sitios de un bosque de pino del Cerro Nambiyugua, Villaflores, Chiapascon el método del Inventario Nacional Forestal y de Suelos. En cada sitio, se utilizaron ocho cuadrantes de 30 x 30 cm2 para colectar las muestras de hojarasca y mantillo. Para el secado de las muestras, se utilizaron bolsas de papel estraza y se colocaron en estufa a 70°C durante 72 horas. El material leñoso caído se determinó con la metodología de interseccion planar. La carga de hojarasca y mantillo aumentó gradualmente con el tiempo Las mayores cargas de hojarasca se obtuvieron en el año 2018 con 12.67 t ha-1. Después del incendio forestal del año 2019, la carga de hojarasca disminuyo a 5.67 t ha-1, y para el 2021 aumento a 8.65 t ha-1. La tendencia de acumulación de material leñoso caído varió según la categoría de horas de ignición. Los resultados de este estudio tienen implicaciones fundamentales en las estrategias y periodicidad del manejo de carga de combustibles forestales y almacenamiento de carbono ya que con el cambio climático se espera mayor frecuencia de incendios forestales.
Molecular characterisation of the current cultivars of <i>Vitis vinifera</i> L. in Lanzarote (Canary Islands, Spain) reveals nine individuals which correspond to eight new varieties and two new sports
Authors: Fort Francesca , Marsal Gemma , Mateo-Sanz Josep Maria , Pena Violeta , Canals Juan Miguel , Zamora Fernando 
Published: September 2022

Vine was reintroduced to the volcanic island of Lanzarote (Spain) more than 300 years ago. The phylloxera plague has never reached the island; consequently, Vitis vinifera L. has evolved continuously since then due to the influence of some abiotic factors, such as low rainfall and strong winds. The aim of this study was to determine the inter- and intra-varietal diversity of the island’s vines and the potential evolution of singularity. Two hundred and twenty-three samples were genotyped with 20 SSR (Simple Sequence Repeats).
The following results were obtained from these analyses: 8 new varieties (Blanca de la granja del cabildo (W), Burra chinija (W), Diego chinija (W), Lemes del Cabezo (W), Malvasia alistanada fina (W), Malvasia alistanada rustica (W) (a mutation of Malvasia alistanada fina), Sinforiano chano (Rs), Uvillón negro (R), Vijariego blanco de la granja (W)), and 2 new sports (Chasselas lajiares (Rs) and Diego de El Raso rosado (Rs)).
In addition, scientific studies on varieties from the island of Lanzarote describe four local cultivars: Breval negro (Rg), Malvasia volcanica (W), Torrontes volcanico (W) and Uva de año (R), which means that a total of 12 local varieties and 2 colour mutations have been described for this Atlantic island. It should also be noted that the appearance of 100 new molecular profiles with their corresponding names represents an unprecedented lexical enrichment. Lanzarote can be considered a centre of biodiversity, as is the Canary archipelago as a whole. Their vines have evolved to such an extent that they are now genetically different from the original populations. The vines from Lanzarote could be of great interest to the wine sector, as they can act as a nursery from which better-adapted vines can be obtained to mitigate the effects of climate change.