bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cryptococcus laurentii Fungaemia in a Neonate from Nigeria: A Case Report
Authors: Ekeng Bassey E. , Adams Emmanuel B. , Udoh Ubong A. , Ita Okokon Ita , Okorafor Linda N. , Monjol Bernard E. , Oteikwu Ochigbo S. , Ikpeme Offiong E. , Oladele Rita O. 
Published: November 2022

Aim: Increasing cases of Cryptococcus laurentii infection are being reported globally possibly due to advances in medicine, the use of immunosuppressants and invasive therapies such as endotracheal intubation, parenteral nutrition, central vascular catheters and exposure to broad-spectrum antimicrobial agents. Cryptococcus species are ubiquitously distributed in the environment, abundant in contaminated soil and bird droppings. Four cases of Cryptococcus laurentii fungemia have been described in neonates, all were premature low/very low-birth-weight. Our case is likely the 5th reported globally and the 1st from Nigeria and Africa across all age groups.
Case Presentation: The patient presented at 34 hours of life with complaints of fever and multiple convulsions after delivery in a traditional birth attendant facility. Mother drained liquor for 5 days with poor cord care. A diagnosis of severe birth asphyxia with sepsis was made and baby received antibiotics (ceftriaxone and genticin) in addition to the management of severe birth asphyxia but showed no improvement. Blood culture yielded cream-colored smooth colonies, identified by Vitek 2 (bioMerieux, France) as Cryptococcus laurentii. Baby was treated with fluconazole, had good recovery and was discharged home.
Conclusion: Our case report emphasizes the need for high index of suspicion for non-bacterial organisms (fungi) as possible causes of sepsis in newborns. Improved fungal diagnosis and timely commencement of antifungal medications will improve clinical outcomes.
Performance and Resource Requirements of In-Person, Voice Call, and Automated Telephone-Based Socioeconomic Data Collection Modalities for Community-Based Health Programs
Authors: Allen Luke N. , Mackinnon Shona , Gordon Iris , Blane David , Marques Ana Patricia , Gichuhi Stephen , Mwangi Alice , Burton Matthew J. , Bolster Nigel , Macleod David , Kim Min , Ramke Jacqueline , Bastawrous Andrew 
Published: November 2022

ImportanceGathering data on socioeconomic status (SES) is a prerequisite for health programs that aim to improve equity. There is a lack of evidence on which approaches offer the best combination of reliability, cost, and acceptability.ObjectiveTo compare the performance of different approaches to gathering data on SES in community health programs.Data SourcesA search of the Cochrane Library, MEDLINE, Embase, Global Health, ClinicalTrials.gov, the World Health Organization International Clinical Trials Registry Platform, and OpenGrey from 1999 to June 29, 2021, was conducted, with no language limits. Google Scholar was also searched and the reference lists of included articles were checked to identify further studies. The search was performed on June 29, 2021.Study SelectionAny empirical study design was eligible if it compared 2 or more modalities to elicit SES data from the following 3 categories: in-person, voice call, or automated telephone-based systems.Data Extraction and SynthesisTwo reviewers independently screened titles, abstracts, and full-text articles and extracted data. They also assessed the risk of bias using Cochrane tools and assessed the certainty of the evidence using the Grading of Recommendations, Assessment, Development and Evaluation approach. Findings were synthesized thematically without meta-analysis.Main Outcomes and MeasuresResponse rate, equivalence, time, costs, and acceptability to patients and health care professionals.ResultsThe searches returned 3943 records. The 11 included studies reported data on 14 036 individuals from 7 countries, collecting data on 11 socioeconomic domains using 2 or more of the following modes: in-person surveys, computer-assisted telephone interviews (CATIs), and 2 types of automated data collection: interactive voice response calls (IVRs) and web surveys. Response rates were greater than 80% for all modes except IVRs. Equivalence was high across all modes (Cohen κ &amp;gt; 0.5). There were insufficient data to make robust time and cost comparisons. Patients reported high levels of acceptability providing data via IVRs, web surveys, and CATIs.Conclusions and RelevanceSelecting an appropriate and cost-effective modality to elicit SES data is an important first step toward advancing equitable effective service coverage. This systematic review did not identify evidence that remote and automated data collection modes differed from human-led and in-person approaches in terms of reliability, cost, or acceptability.
Boosting Industrial‐Level CO2 Electroreduction of N‐Doped Carbon Nanofibers with Confined Tin‐Nitrogen Active Sites via Accelerating Proton Transport Kinetics
Authors: Hu Xiangzhao , Liu Yingnan , Cui Wenjun , Yang Xiaoxuan , Li Jiantong , Zheng Sixing , Yang Bin , Li Zhongjian , Sang Xiahan , Li Yuanyuan , Lei Lecheng , Hou Yang 
Published: November 2022

AbstractThe development of highly efficient robust electrocatalysts with low overpotential and industrial‐level current density is of great significance for CO2 electroreduction (CO2ER), however the low proton transport rate during the CO2ER remains a challenge. Herein, a porous N‐doped carbon nanofiber confined with tin‐nitrogen sites (Sn/NCNFs) catalyst is developed, which is prepared through an integrated electrospinning and pyrolysis strategy. The optimized Sn/NCNFs catalyst exhibits an outstanding CO2ER activity with the maximum CO FE of 96.5%, low onset potential of −0.3 V, and small Tafel slope of 68.8 mV dec−1. In a flow cell, an industrial‐level CO partial current density of 100.6 mA cm−2 is achieved. In situ spectroscopic analysis unveil the isolated SnN site acted as active center for accelerating water dissociation and subsequent proton transport process, thus promoting the formation of intermediate *COOH in the rate‐determining step for CO2ER. Theoretical calculations validate pyrrolic N atom adjacent to the SnN active species assisted reducing the energy barrier for *COOH formation, thus boosting the CO2ER kinetics. A Zn‐CO2 battery is designed with the cathode of Sn/NCNFs, which delivers a maximum power density of 1.38 mW cm−2 and long‐term stability.
Revealing the Intrinsic Uneven Electrochemical Reactions of Li Metal Anode in Ah‐Level Laminated Pouch Cells
Authors: Duan Xiangrui , Wang Lingyue , Li Guocheng , Liu Xueting , Wan Mintao , Du Junmou , Zhan Renming , Wang Wenyu , Li Yuanjian , Tu Shuibin , Shen Yue , Seh Zhi Wei , Wang Li , Sun Yongming 
Published: November 2022

AbstractThe uneven electrochemical reactions of lithium (Li) metal anode is one of the main reasons that hinder its application in rechargeable high energy density batteries. Great progress has been achieved in homogenizing electrochemical reactions of Li metal anode in lab‐scale coin cells, however, it cannot be directly applied to pouch cells, where undesirable defects or side reactions are significantly aggravated. With carbonate electrolyte, multi‐layered negative and positive electrodes (8 × 11 cm), 1.2 Ah sulfurized polyacrylonitrile (SPAN)||Li pouch cell lost all its capacity after 40 cycles under a current of 600 mA, although its counterpart with coin cell configuration showed much higher capacity retention of 94% under the same test condition. Severe corrosion with uneven, porous, dendritic Li deposits is observed for pristine Li electrode in a pouch cell, especially in the near‐tap and the central regions with close connection with the current collector due to the locally amplified current densities. In contrast, Li/Li–Sn alloy composite electrode displays uniform and dense Li plating behavior over the entire test area with significantly suppressed parasitic reactions and gas evolution. As such, a 1.2 Ah SPAN||Li/Li–Sn cell displays much higher capacity retention than SPAN||Li cell (87% for 100 cycles vs. 0 for 40 cycles).
An Organic Electrochemical Transistor Integrated Photodetector for High Quality Photoplethysmogram Signal Acquisition
Authors: Zhong Yizhou , Koklu Anil , Villalva Diego Rosas , Zhang Yongcao , Hernandez Luis Huerta , Moser Maximilian , Hallani Rawad K. , McCulloch Iain , Baran Derya , Inal Sahika 
Published: November 2022

AbstractThe organic photodiode (OPD) is a promising building block for solution‐processable, flexible, lightweight, and miniaturized photodetectors, ideal for wearable applications. Despite the advances in materials used in OPDs, their photocurrent and light responsivity are limited, and alternative methods are required to boost the signal response. Herein, a miniaturized organic electrochemical transistor (OECT) is integrated with an OPD module to unlock the potential of OPDs to acquire physiological signals. In this integrated photodetector (IPD) system, the light intensity regulates the OPD voltage output that modulates the OECT channel current. The high transconductance of the OECT provides efficient voltage‐to‐current conversion, enhancing the signal‐to‐noise ratio on the sensing site. A microscale, p‐type enhancement‐mode OECT with high gm and fast switching speed performs better in this application than depletion‐mode OECT of the same geometry. The IPD achieves a photocurrent and responsivity 318 and 140 times higher than the standalone OPD, respectively. It is shown that with the IPD, the amplitude of the photoplethysmogram signals detected by the OPD is enhanced by a factor of 2.9 × 103, highlighting its potential as a wearable biosensor and to detect weak, often uncaptured, light‐based signals from living systems.
A Universal Graphene‐Selenide Heterostructured Reservoir with Elevated Polysulfide Evolution Efficiency for Pragmatic Lithium–Sulfur Battery
Authors: Wang Menglei , Zhu Yujie , Sun Yingjie , Zhao Yu , Yang Xianzhong , Wang Xiaojing , Song Yingze , Ci Haina , Sun Jingyu 
Published: November 2022

AbstractThe practical application of lithium–sulfur (Li–S) batteries has been handicapped by the notorious polysulfide shuttling and sluggish sulfur conversion kinetics. Although the functional modification of separator is readily proposed as an effective strategy to optimize the Li–S redox reactions, the excessive material dosage and invalid structural design still result in inferior electrocatalyst utilization. Herein, generic graphene‐metal selenide heterostructures (Gr‐MxSey, M = Mo, W, Mn, Cu and Zn) are controllably grown on commercial glass fiber (GF) separator employing a sequential low‐temperature chemical vapor deposition procedure. Such a tailored reservoir can not only render ample active sites but also realize the synergy of polar and catalytic framework, which maximizes the electrochemical functions in alleviating shuttle effect and guiding Li2S nucleation/decomposition. The thus‐derived Gr‐MxSey/GF separator affording favorable heatproof feature endows the Li–S battery with an outstanding cycling stability (100% capacity retention over 100 cycles at 0.2 C). Furthermore, the flexible Li–S pouch cell based on this new separator delivers good device performance (with a capacity decay of 0.25% per cycle over 100 cycles). This study offers comprehensive insight into the reliable separator design toward working Li–S batteries.
An Organic Electro‐Mechanical Cavity Emitting Efficiently Tunable, Continuous‐Wave‐Pumped Nonlinear‐Optical Modes
Authors: Mitetelo Nikolai , Ravi Jada , Mondal Subrata , Venkataramudu Uppari , Mamonov Evgeniy , Popov Mikhail , Maydykovskiy Anton , Vaitheeswaran Ganapathy , Murzina Tatiana , Chandrasekar Rajadurai 
Published: November 2022

AbstractOrganic polar crystals are a promising material platform for achieving unique nonlinear nanophotonic properties. Mainly, tunable second‐harmonic generation (SHG) with continuous‐wave (CW) pump sources is considered as breakthrough technology for optical switching, actuation, sensing, chip‐integrated coherent light sources, and low‐threshold tunable microlasers. Here, the discovery of tunable CW SHG in a polar (non‐centrosymmetric) electro‐mechanical microcrystal cavity of 4‐(4‐(methylthio)phenyl)‐2,6‐di(1H‐pyrazol‐1‐yl)pyridine (UOH1) is demonstrated. As a result of total internal reflection in mirror‐like light‐reflecting facets and its high second‐order nonlinear susceptibility, the octahedron‐shaped cavities exhibit both bright femtosecond and CW‐pumped SHG with coherent whispering gallery mode (WGM) and bow‐tie‐like (BT) optical modes excited in its spectrum. Moreover, for an external dc electric field of about 23 kV cm−1 the microcavity displays 0.18 nm resonant wavelength peak shift in the second harmonic signal due to electrostriction (strain effect).
Modulating Nanozyme‐Based Nanomachines via Microenvironmental Feedback for Differential Photothermal Therapy of Orthotopic Gliomas
Authors: Yin Na , Wang Yinghui , Huang Ying , Cao Yue , Jin Longhai , Liu Jianhua , Zhang Tianqi , Song Shuyan , Liu Xiaogang , Zhang Hongjie 
Published: November 2022

AbstractGliomas are common and refractory primary tumors closely associated with the fine structures of the brain. Photothermal therapy (PTT) has recently shown promise as an effective treatment for gliomas. However, nonspecific accumulation of photothermal agents may affect adjacent normal brain structures, and the inflammatory response induced during PTT may result in an increased risk of brain tumor recurrence or metastasis. Here, the design and fabrication of an intelligent nanomachine is reported based on Gd2O3@Ir/TMB‐RVG29 (G@IT‐R) hybrid nanomaterials. These nanomaterials enable tumor‐specific PTT and eliminate inflammation to protect normal brain tissue. The mechanism involves the rabies virus glycopeptide‐29 peptide (RVG29) passing through the blood–brain barrier (BBB) and targeting gliomas. In the tumor microenvironment, Ir nanozymes can act as logic control systems to trigger chromogenic reaction amplification of 3,3′,5,5′‐tetramethylbenzidine (TMB) for tumor‐specific PTT, whereas in normal brain tissues, they scavenge reactive oxygen species (ROS) generated by poor therapy and function as protective agents. Autophagy inhibition of Gd2O3 enables excellent photothermal therapeutic effects on orthotopic gliomas and protection against inflammation in normal cells. The results of this study may prove useful in developing highly efficient nanomedicines for glioma treatment.
Rheological and mechanical behavior of non‐spherical poly(lactic acid) particles embedded poly(butylene adipate‐co‐terephthalate) blend
Authors: Chung Hye Young , Hong Joung Sook , Ahn Kyung Hyun 
Published: November 2022

AbstractIn this study, the poly(lactic acid) (PLA)/poly(butylene adipate‐co‐terephthalate)(PBAT) blend is investigated to improve rheological and mechanical performances of PBAT based on rheological, mechanical, and thermal behavior analyses. The multi‐step mixing method is developed to fabricate the blend with non‐spherical morphology. In the multi‐step mixing method, blends with a wide composition range (25/75–75/25) are mixed with additional PBAT at a mixing temperature between the melting temperatures of PBAT and PLA to produce the PBAT blend embedded with non‐spherical PLA particles (10 wt%). The embedding of non‐spherical PLA particles in PBAT increases the resistance against deformation, resulting in strain hardening behavior and an increase in the yield strength as well as the tear resistance of the PBAT. The presence of stiff PLA particles enhances the crystallization behavior of PBAT, meaning that polymer chains may interpenetrate. The findings of this study suggest that the multi‐step mixing method is beneficial for embedding non‐spherical PLA particles into a PBAT matrix, which in turn facilitates the maintenance of good interfacial adhesion to increase the melt strength, yield strength, and tear resistance.
Study on preparation and anticorrosive performance of a new high hydrophobic anticorrosive coating
Authors: Zhang Jian , Zhang Xiangdong , Liu Zhongyuan , Zhang Lanhe , Zhao Yue , Li Yuanchun , Shao Chen , Ren Junlian 
Published: November 2022

AbstractWater‐based anticorrosive coatings have poor water resistance, which easily lead to coating deterioration and metal corrosion. In order to improve the anticorrosion performance of waterborne coating, herein, the polytetrafluoroethylene/dimethyl siloxane/epoxy resin (PTFE/PDMS/EP) hydrophobic anticorrosive coating was prepared by layer‐by‐layer construction. The spatial structure and microscopic morphology of the hydrophobic coating were analyzed by XRD, FTIR, and SEM. The hydrophobicity and corrosion resistance of the composite coating were analyzed by hydrophobicity test, electrochemical polarization curve, hydrophobicity and corrosion resistance test of the mixed layer, Tafel polarization curves, and AC impedance spectrum. The results showed that the water contact angle of PTFE/PDMS/EP coating reached 141° and the protection efficiency of PTFE/PDMS/EP coating was 98.62%. After soaking for 7 days, the corrosion process still stays at the initial stage, which was mainly due to the good sealing and barrier properties and high anticorrosion efficiency of PTFE/PDMS/EP coating. The coating has high corrosion protection efficiency and long service life, which is of great significance to metal corrosion protection in harsh marine environments.
Flexible supercapacitors toward wearable energy storage devices
Authors: Muniraj Vedi Kuyil Azhagan , Srinivasa Madhusudana Koratikere , Yoo Hyun Deog 
Published: November 2022

AbstractThe expeditiously growing wearable, thin, and flexible electronics have created a great demand for futuristic miniaturized charge storage devices. As power sources, flexible supercapacitors (FSCs) have received huge attraction because of their reliability, compatibility, and safety within the integrated lightweight consumer device applications. Along with high specific power and durability, the FSC provides a novel platform that inspires creative applications. Thereupon, the FSCs have become one of the most favorable candidates for energy storage in various forms such as skin patches or printed/wearable fabrics that can be used in medical examination. In this review, we focus on the current progress in the development of flexible electrode materials and scalable fabrication processes for FSC devices. Prospects in developing new approaches toward improved energy and power densities are highlighted.
Classical Ehlers–Danlos syndrome with severe kyphoscoliosis due to a novel pathogenic variant of COL5A2
Authors: Foy Malika , de Mazancourt Philippe , Bremond Gignac Dominique , Gillas Fabrice , Trigui Nawel , Mekki Ahmed , Carlier Robert , Benistan Karelle 
Published: November 2022

AbstractWe described a novel de novo missense variant of the gene encoding Collagen alpha‐2(V) chain, associated with the classical Ehlers–Danlos syndrome (cEDS) (OMIM#130010), in a 14‐year‐old patient who presented with congenital and severe scoliosis, muscle hypotonia, ocular manifestations, and no atrophic scaring. This case expands the phenotypic spectrum of cEDS.
Submucosal administration of dexamethasone for dental implant surgery
Authors: Flanagan Dennis 
Published: November 2022

AbstractDexamethasone can reduce post‐operative pain and swelling. An appropriate administration of dexamethasone for dental surgical procedures may be local submucosal infiltration. Local delivery may produce a faster onset with more drug at the desired site of action. A single submucosal dose will unlikely produce side effects.
Ultrasound‐assisted management of filler‐related complications: Report of a successful treatment of delayed‐onset nodules related to polycaprolactone‐based filler
Authors: Shekarriz Pantea , Shojaee Pardis 
Published: November 2022

AbstractA 60‐year‐old woman underwent polycaprolactone‐based filler injection in her midface. Four months later, she developed progressive swelling of midface after a self‐limiting viral gastroenteritis. The diagnosis was “delayed‐onset immune‐mediated nodule formation triggered by a virus.” Ultrasonography enabled us to efficiently treat her with a tailored intralesional corticosteroid injection method.
Isolated unilateral absence of adult pulmonary artery
Authors: Yamamoto Koichiro , Nakano Yasuhiro , Otsuka Fumio 
Published: November 2022

AbstractIsolated unilateral absence of pulmonary artery (UAPA) is a rare congenital malformation. We describe a 26‐year‐old woman with isolated UAPA who presented with hemoptysis. Since massive hemoptysis may mandate selective embolization of collaterals or surgical treatment, early diagnosis of UAPA is pivotal.
Pena–Shokeir syndrome's first case report from Syria
Authors: Almoshantaf Mohammad Badr , Alibrahim Hidar , Bohsas Haidara , Alabdo Shorouk , Nashwan Abdulqadir J. , Swed Sarya 
Published: November 2022

AbstractPena–Shokeir syndrome is considered to be a fatal congenital condition that is rarely diagnosed in neonates. We present the first‐ever reported case of Pena–Shokeir syndrome from Syria. Clinical assessment and early prenatal diagnosis are both needed to give the mother and baby more realistic options.
Cellulose‐Phytic Acid Composite Complexed Ru Catalyst for CO2 Hydrogenation to Free Formic Acid
Authors: Wang Ying , Zeng Wei , Zhao Yanfei , Tang Minhao , Chang Xiaoqian , Xu Yueting , Li Rongxiang , Liu Zhimin 
Published: November 2022

AbstractThe CO2 hydrogenation to free formic acid is an interesting topic, and low‐cost and high‐performance catalysts are highly desirable. This work presents a simple and green strategy to prepare high‐performance Ru catalysts for CO2 hydrogenation using cellulose and phytic acid composite (CPC) as support to complex with Ru(III). The CPC support prepared with assistance of 1‐butyl‐3‐methyl imidazolium chloride exhibits porous structure with abundant free −OH and −PO4 groups that can complex with Ru(III). The CPC complexed Ru catalyst (e. g., CPC‐Ru‐1) showed much higher activity for CO2 hydrogenation to formic acid in 1‐butyl‐3‐methyl imidazolium acetate than the reported heterogeneous Ru catalysts. Especially, CPC‐Ru‐1 with 0.094 wt% Ru afforded formic acid in selectivity >99 % with a turnover number around 1.8×104 and an initial production rate of 15.21 mol ⋅ g−1 ⋅ h−1 within the first 2 h at 120 °C. This catalyst is recyclable and stable without obvious activity loss after 5 runs.
Photocatalytic Hydrogen Evolution by a De Novo Designed Metalloprotein that Undergoes Ni‐Mediated Oligomerization Shift
Authors: Prasad Pallavi , Hunt Leigh Anna , Pall Ashley E. , Ranasinghe Maduni , Williams Ashley E. , Stemmler Timothy L. , Demeler Borries , Hammer Nathan I. , Chakraborty Saumen 
Published: November 2022

AbstractDe novo metalloprotein design involves the construction of proteins guided by specific repeat patterns of polar and apolar residues, which, upon self‐assembly, provide a suitable environment to bind metals and produce artificial metalloenzymes. While a wide range of functionalities have been realized in de novo designed metalloproteins, the functional repertoire of such constructs towards alternative energy‐relevant catalysis is currently limited. Here we show the application of de novo approach to design a functional H2 evolving protein. The design involved the assembly of an amphiphilic peptide featuring cysteines at tandem a/d sites of each helix. Intriguingly, upon NiII addition, the oligomers shift from a major trimeric assembly to a mix of dimers and trimers. The metalloprotein produced H2 photocatalytically with a bell‐shape pH dependence, having a maximum activity at pH 5.5. Transient absorption spectroscopy is used to determine the timescales of electron transfer as a function of pH. Selective outer sphere mutations are made to probe how the local environment tunes activity. A preferential enhancement of activity is observed via steric modulation above the NiII site, towards the N‐termini, compared to below the NiII site towards the C‐termini.