bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Perubahan Lahan Dan Iklim Terhadap Ketersediaan Airtanah Pada Subdas Cibeureum (Kawasan Bandung Utara)
Authors: Suganda Bombom Rachmat , Hani Fauziyah , Hadian Sapari Dwi , Barkah Muhammad Nursiyam , Listiawan Yudhi 
Published: July 2022

SubDAS Cibeureum merupakan bagian dari DAS Citarum. SubDAS Cibeureum merupakan bagian dari Kawasan Bandung Utara. Seiring pertumbuhan penduduk yang meningkat, pembangunan pun terus terjadi sehingga mengubah tutupan lahan dari hutan menjadi pemukiman, jalan, industri, bahkan kawasan ini sangat diminati untuk dijadikan tempat wisata padahal disisi lain area ini harus dilindungi karena merupakan kawasan resapan air. Selain perubahan lahan, perubahan iklim juga akan mempengaruhi potensi air. Oleh karena itu untuk melihat pengaruh perubahan lahan dan iklim terhadap potensi air dilakukan perhitungan ketersediaan air menggunakan metode neraca air thornthwaite. Parameter yang digunakan adalah data curah hujan dan suhu dari stasiun BMKG Bandung tahun 2007-2017 dan data penutupan lahan Jawa Barat tahun 2009, 2012 dan 2017. Rata-rata curah hujan periode 2007-2009 sebesar 2084.7 mm/tahun, periode 2010-2012 sebesar 2664.3 mm/tahun, sedangkan periode 2013-2017 sebesar 2583 mm/tahun Rata-rata evapotranspitrasi periode 2007-2009 sebesar 1188.94 mm/tahun, periode 2010-2012 sebesar 1194.41 mm/tahun, dan periode 2013-2017 sebesar 1210.71 mm/tahun. Karena adanya perubahan lahan, maka koefisien <em>run off</em> meningkat dari 0.26 (2009), 0.31 (2012), dan 0.375 (2017). Dari hasil perhitungan didapat bahwa dari tahun 2007-2012, kawasan ini mengalami perubahan lahan yang mengakibatkan kenaikan debit <em>run off</em> dan perubahan iklim yang mengakibatkan kenaikan debit presipitasi efektif. Dan dari hasil penelitian didapat bahwa ketersediaan air meningkat pada tahun 2012 karena curah hujan yang meningkat cukup besar pada periode tahun 2010-2012
Showing Leadership through the types of Presupposition in Patriots Day Movie
Authors: Prasetyani Nuning Yudhi , Fitriana Irta , Febriani Eka 
Published: July 2022

This study is a pragmatics scope that focused on types and meaning of presupposition in Patriots Day movie which was uttered by the main character (Tommy) by using George Yule’s theory. The movie is a documentary movie that told about true story of bombing action at Boston marathon in 2013. Then, this study also applied qualitative research that uses description and sampling data to be analyzed. In Yule’s theory, he classified six types of presupposition; there are existential, factive, lexical, structural, non-factive and counterfactual presupposition. The result of this study was that all of types were applied by Tommy but existential presupposition was used more frequent than other types. Existential presupposition found 78 data, structural is 19 data, factive is 5 data, lexical also is 4 data, non-factive was 2 data and counter-factual is2 data. Existential presupposition is commonly shown because Tommy as the main character is a sergeant/ leader. He has power, authority and wants to show the existence of situation, condition, people around him and himself by saying utterances that contain its presupposition. Later, he also wants and strives to cover his feeling, weakness, mental pressure from his interlocutors Thus, existential presupposition is more used by Tommy to show the situation that he faced, the power of Tommy as a sergeant and represent his mental pressure during his duty.
Derivatization of Inseparable Ursolic and Oleanolic Acids of Fagraea fragrans Fruits to Enhance Their Anticancer Activity
Authors: Basir Dasril , Miksusanti Miksusanti , Susilawati Susilawati 
Published: July 2022

Inseparable Ursolic acid and its isomeric oleanolic acid are the major compounds in Fagraea fragrans fruits. The white solid crystals , 3.1 % of these triterpenic acids are easyly isolated from alcoholic extracts of these dried fruits. They are well known in both cosmeticeutical and medicinal industries. Therefore the objective of this work is to derivative those to be the inseparable ethyl ursolate 3-ethyl ether [its isomeric ethyl oleanolate 3-ethyl ether], and to evaluate their anticancer activity against P-388 murine leukemia cells. The results are 71% of the derivatives have been successfully made from the inseparable ursolic [its isomeric oleanolic] acids by in situ reaction between those triterpenic acids with thionyl chloride and ethanol in benzene. The anticancer activity of ethyl ursolate 3-ethyl ether [its isomeric ethyl oleanolate 3-ethyl ether] against P-388 murine leukemia cells with IC50 value of 31.36 µg/mL is twofold (1.7) more potent then their mother compounds, the inseparable ursolic [its isomeric oleanolic] acids with IC50 value of 53.5 µg/mL.
Chiral Separation of Econazole by High Performance Liquid Chromatography Method using Cyclodextrin as Chiral Column
Authors: Hermawan Dadan , Cacu Cacu , Salsabila Khansa , Suwandri Suwandri , Fatoni Amin , Sulaeman Uyi , Iswanto Ponco , Mudasir Mudasir , Aboul-Enein Hassan Y. 
Published: July 2022

The chiral separation of econazole, an antifungal drug with one chiral center has been successfully carried out using the high-performance liquid chromatography (HPLC) method. Enantioresolution of econazole (Rs = 2.29) was achieved using cyclodextrin-based chiral column (Astec Cyclobond, 25 cm × 4.6 mm × 5 μm), mobile phase composition of acetonitrile : water (0.2% HCOOH) (20:80, v/v), and UV detection of 220 nm.The optimized HPLC method has been applied for the quantitative determination of econazole in the pharmaceutical (liquid) sample withpercentage recovery of 100.75 % (RSD = 0,95%; n = 3). The effect of several HPLC parameters on the chiral separation of econazole was also evaluated and the method was successfully validated in terms of linearity, accuracy, precision, and selectivity. The present HPLC method was simple, short analysis time, and high resolution.
PENGARUH PEMBERIAN PROPOLIS TERHADAP EKSPRESI BDNF DI HIPPOCAMPUS TIKUS YANG DIINDUKSI STRES
Authors: Kuswati Kuswati , Nugraha Zainuri Sabta , Handayani Ety Sari 
Published: July 2022

Latar belakang: Brain-derived neurotrophic factor (BDNF) merupakan neurotrophin yang disekresi oleh dendrit. BDNF berperan pada diferensiasi, maturasi dan menjaga survival neuron. BDNF juga berperan penting pada neuroplastisitas, learning and memory. Ekspresi BDNF menurun pada kondisi stres. Propolis mengandung chyrisin yang memiliki efek antioksidan dan neuroprotektan. Penelitian ini ingin melihat efek propolis terhadap ekspresi BDNF pada hippocampus tikus yang diinduksi stres.Tujuan: untuk mengetahui pengaruh pemberian propolis terhadap ekspresi BDNF di hippocampus pada tikus yang diinduksi stres.Metode: Penelitian eksperimental dengan menggunakan rancangan posttest only control group design. Subjek penelitian ini tikus Rattus norvegicus jantan, berumur 4 bulan dengan berat badan 200-300 gram dari galur Spraque-Dawley. Tikus dibagi secara random menjadi 5 kelompok, masing-masing kelompok terdiri dari 5 ekor tikus. Kelompok N tidak mendapat perlakuan. Kelompok K mendapat perlakuan stres, kelompok P1, P2 dan P3 mendapat perlakuan stres dan pemberian propolis dosis 100, 150 dan 200 mg/kgbb/hari. Perlakuan stres menggunakan model stres isolasi sosial. Pemberian propolis secara oral menggunakan sonde. Perlakuan stres dan pemberian propolis selama 14 hari. Hari ke-15 dilakukan terminasi dan pengambilan jaringan otak. Selanjutnya dilakuakan pembuatan sediaan histologis dengan pewarnaan imunohistokimia menggunakan antibodi anti BDNF. Pengamatan menggunakan mikroskop cahaya dengan perbesaran 1000 kali pada area CA1 hippocampus.Hasil: Terdapat perbedaan signifikan ekspresi BDNF di area CA1 hippocampus pada semua kelompok (p. 0.000). Ekspresi BDNF tertinggi pada kelompok P3. Ekspresi terendah pada kelompok K. Kesimpulan: Terdapat pengaruh pemberian propolis terhadap ekspresi BDNF pada hippocampus tikus yang diinduksi stres. Dosis propolis 100,150 dan 200mg/kgbb meningkatkan ekspresi BDNF.
Kajian Literatur: Profil Resistensi Salmonella typhi dan Pemilihan Antibiotik Pada Demam Tifoid
Authors: Sanjaya Dwi Arymbhi , Meriyani Herleeyana , Juanita RR. Asih , Siada Nyoman Budiartha 
Published: July 2022

<p>Demam tifoid merupakan penyakit infeksi yang disebabkan oleh bakteri Gram-negatif yaitu <em>Salmonella typhi</em>. Munculnya <em>multidrug-resistant Salmonella typhi </em>(MDRST) dan <em>extensively drug-resistant</em> (XDR) <em>Salmonella typhi </em>menjadi ancaman baru dalam keberhasilan terapi demam tifoid. Efektivitas terapi pada demam tifoid memerlukan kajian tentang profil resistensi <em>Salmonella typhi </em>terhadap antibiotik yang diamati dari <em>minimum inhibitory concentration </em>(MIC) dan mutasi genetika<em>, </em>sehingga dapat dilakukan pemilihan antibiotik yang tepat pada demam tifoid dengan MDR dan XDR <em>Salmonella typhi</em>. Kajian literatur ini mengumpulkan dan menelaah informasi yang diperoleh dari hasil-hasil penelitian dari berbagai artikel internasional tentang resistensi <em>Salmonella typhi </em>terhadap antibiotik pada deman tifoid. Pencarian artikel menggunakan <em>database PubMed</em>, <em>PlosOne</em>, dan <em>ScienceDirect</em> sejak tahun 2011 hingga September 2021. Artikel yang diperoleh dari 192 artikel, terdapat delapan (8) artikel yang relevan, yang mana diketahui bahwa isolat <em>Salmonella thypi</em> resisten terhadap Ampisilin, Amoksisilin, kombinasi Amoksisilin-Asam Klavulanat, Kloramfenikol, Siprofloksasin, Ofloksasin, Levofloksasin, Asam Nalidiksat, Trimetoprim, dan kombinasi Trimetoprim-Sulfametoksazol yang diamati pada MIC<sub>90</sub>. Nilai MIC akan berdampak pada penentuan dosis yang efektif untuk mencapai konsentrasi terapetik sehingga dapat mempengaruhi indeks farmakokinetik dan farmakodinamik. Gen yang bertanggung jawab terhadap MDRST dan XDR <em>Salmonella typhi </em>yaitu: <em>bla</em><sub>TEM-1</sub>, <em>cat</em>A, <em>dhfr</em>1<em>b</em>, <em>sul</em>1, <em>sul</em>2, <em>class </em>1 <em>integron</em>, <em>gyr</em>A dan <em>gyr</em>B, serta <em>par</em>C. Azitromisin dan Seftriakson menjadi pilihan terapi utama untuk terapi empiris pada demam tifoid. Adanya nilai MIC dan parameter farmakokinetik/farmakodinamik dapat digunakan untuk menginterpretasikan sensitivitas bakteri terhadap antibiotik, yang dapat digunakan sebagai salah satu rujukan dalam menyusun kebijakan penggunaan antibiotik. </p>
Manajemen Kecerdasan Emosi dan Penerapan Administrasi Skrining Penyakit Tidak Menular bagi Kader Posyandu
Authors: Kesetyaningsih Tri Wulandari Wulandari , Mahanggoro Tri Pitara 
Published: July 2022

<p><strong><em>Background :</em></strong><em> Gamping Kidul hamlet is growing fast as an educational center. This condition brings socio-economic changes and unhealthy lifestyles so that there are concerns about an increase in non-communicable diseases (NCDs). This Community Service (CS) is a continuation of the previous CS which has formed a care group of healthy lifestyles and provides cadres with NCDs screening and prevention. These activities were enhanced by training on emotional intelligence management and screening administration. The activity aims to train management emotions and apply NCDs screening administration so that it can further strengthen the ability of cadres to implement NCDs prevention programs. </em></p><p><strong><em>Methods :</em></strong><em>The service is carried out with explanation, discussion, and practice. At the end of the training, an assessment of the level of emotional intelligence is carried out. </em></p><p><strong><em>Results :</em></strong><em> The training was attended by 14 integrated service post cadres (posyandu) as participants. The results of the assessment show that 57% of cadres have high emotional intelligence, 29% are moderate and 14% are low. Emotional intelligence of non-cadres is 84.62% high and 7.69% moderate and low, respectively. The Mann Whitney test proves that the emotional intelligence of cadres is significantly lower than that of non-cadres. </em></p><p><strong><em>Conclusion :</em></strong><em> It was concluded that most posyandu cadres had high emotional intelligence, some were moderate-low, but lower than non-cadres in average. Posyandu has never done NCDs screening. The training has provided experience in NCDs screening for posyandu cadres</em>.<em></em></p>
SUBSTANTIATION OF THE ELECTROLYTE COMPOSITION IN THE ELECTROCHEMICAL SYNTHESIS OF PEROXYLIC ACID
Authors: Serhii Alexandrovich Vodolazhenko  , Svitlana Germanivna Deribo  , Tetiana Vasylivna Shkolnikova  , Issam Hussein Chahine  
Published: July 2022

lactic acid (PLA) is a strong disinfectant with a wide spectrum of antimicrobial activity. Its widespread use is hampered by the lack of an electrochemical technology for PLA synthesis, which will make it possible to develop local electrochemical generators for the production of disinfectants. There is no information about the standard potential of the СН3СH(OH)С(=О)ОН « СН3СH(OH)С(=О)ООН system, both in reference literature and professional scientific publications. It has been shown that the electrochemical synthesis of PLA will be combined with the processes of oxygen release and the formation of hydrogen peroxide. To inhibit side processes, an additive to a solution of lactic acid 0.5 mol dm-3 H2SO4 was used. The adsorption of sulfate ions leads to the displacement of a certain proportion of water molecules outside the boundaries between the phase boundaries. An almost 2-fold increase in the anodic current density was also noted at the potentials of electrochemical synthesis of peroxide compounds. It has-been found that a lactic acid molecule is integrated into the structure of the near-electrode layer with a carboxyl group directed towards the anode surface. The inflection of the current-voltage curve, at potentials more positive than 1.70...1.75 V, indicates the course of the combined processes of the formation of peroxide compounds, proceeding with a significant inhibition of the oxygen reaction at the Pt/PtO2 anode. The release of oxygen under these conditions occurs due to the formation and destruction of H2O2. The potential difference between the forward and reverse runs of the current-voltage curve indicates a significant effect of lactic acid on the adsorption processes on the anode surface. The results obtained confirmed the relevant the choice of the Pt/PtO2 anode for the electrochemical synthesis of PLA. The characteristics of the electrolyte for the electrochemical synthesis of PLA has been defined: 2 mol dm-3 of lactic acid, 0.5 mol dm-3 of sulfuric acid.
Assessments of tobacco control policy instruments status and effectiveness in Africa; A systematic literature review
Authors: Munthali George N. Chidimbah , Xuelian Wu ,   3Dr. Muhammad Rizwani, Daru Gama Rivas , Yu Shi 
Published: July 2022

Abstract

Background: Tobacco is one of the well-established industries in the world. Despite having some economic benefits, the industry has been for decades associated with environmental problems through deforestation, health related diseases that cause about 8 million mortality rates yearly, human rights violations and corruptions issues which are involved, World Health Organization formulated Framework Convention on Tobacco Control with the aim of controlling tobacco production and consumption, with countries from Africa being ones where its usage is increasing more. Objectives: The main aim of this study was to find out the current status of tobacco control policies and its effectiveness in Africa. Methods: This study was a systematic literature reviews that was conducted between the months of August and November 2020 through extracting data from the database of PubMed, Scopus, Google scholar and Research Gate. Only English articles were selected. Results: Out of 910 papers retrieved only 17 papers from African countries were selected on the quality thesis after meeting the inclusion criteria. The results of the study showed that three governance resources were identified of Regulatory 64.70 % N=14 which had Smoke free environment, Advertisement bans, and cessation programs, economics 24.41% N=6 which were taxation's measures and informative 5.886% N=1 which were mass media campaigns. Further, Western African countries especially South Africa reported many pronouncements on smoke free environments and taxation measures. Mass media campaigns proved to be more effective policy as compared to others. Conclusion: This study recommends that future research should be done on looking at the effectiveness of mixed policy instruments as compared to single application. Further, the researcher recommends the use of more informative policies in dealing with inelastic behaviors like those related to tobacco due to the addictive nature.
Postoperative Pain After Cesarean Section at University of Gondar Comprehensive Specialized Hospital, Gondar, Northwest Ethiopia, 2019; A Cross-Sectional Follow-up Study
Authors: Demelash Getamesay , Woldegerima Yophtahe , Hailekiros Amare , Birlie Wubie 
Published: July 2022

Abstract
Background: Cesarean section is one of the most common obstetric procedures worldwide. Following this, parturients experience moderate to severe pain in the acute postoperative period. Therefore, in resource-limited settings, for full utilization of basic analgesic modalities and to take appropriates interventions, it is vital to know about the magnitude of the problem and its factors.Objective: To assess the prevalence and factors associated with postoperative pain after cesarean section at the University of Gondar Comprehensive Specialized Hospital (UoGCSH), Northwest Ethiopia, 2019.Methods: A hospital-based prospective follow-up study was conducted among parturients who undergo cesarean section in the University of Gondar Comprehensive Specialized Hospital, from mid-February to April 20, 2019, after approval of the ethical review committee. Consecutively, a total of 290 parturients were included with a response rate of 97%. To measure pain severity numerical rating scale was used. Data was entered into Epi-data version 4.2 and analyzed by SPSS version 20 (IBM Corporate). The association between independent factors and the outcome variable was determined at 95% CI with the chi-squared test, bivariate, and multivariate logistic regression. Hosmer-Lemeshow test was used to assess the goodness of fit. Variables with a p-value of < 0.05 were considered significant.Results: In this study, the incidence of moderate to severe post-operative pain after cesarean section was 85.5% (95% CI: 81.4%, 89.0%) within the first 24 postoperative hours. On the multi-variable analysis, preoperative anxiety (AOR: 2.3, 95% CI: 1.1, 4.9), history of previous cesarean section (AOR: 2.3, 95% CI: 1.1, 5.0), Pfannenstiel incision (AOR: 3.2, 95% CI: 1.3, 8.0) and absence of regional analgesia (AOR: 3.7, 95% CI: 1.7, 7.9) were significantly associated with moderate to severe postoperative pain after cesarean section.Conclusions: In this study, a large proportion of parturients had experienced moderate to severe post-cesarean pain in the first 24 postoperative hours. Preoperative anxiety, history of previous cesarean section, Pfannenstiel incision, and parturients with no regional analgesia were significantly associated with post-cesarean pain. Pain severity needs to be assessed and documented by using pain-rating scales and there should be an interdisciplinary approach to provide adequate pain management in our hospital.
Digital Soil Mapping for the Parnaíba River Delta, Brazilian Semiarid Region
Authors: Amorim João Victor Alves , Valladares Gustavo Souza , Pereira Marcos Gervasio , Portela Mirya Grazielle Torres , Lima Andréa Maciel 
Published: July 2022

Abstract
Soil mapping is a permanent demand, but the traditional method does not allow fast execution and low cost. Digital soil mapping (DSM) aims to improve the process by working with models that treat soil spatial variability quantitatively. In this perspective, the objective of the study is to perform DSM of the Parnaíba River Delta, Northeastern Brazil, through the decision tree (DT) integration technique using a set of attributes derived from the digital elevation model (DEM) and satellite images as input parameters. Data matrices were created considering different soil groups. The performance of the J48 machine learning algorithm (DT) was assessed for a set of 2 data matrices. From the data processing, digital soil maps were created and validated by means of error matrices, whose reference points were classified in the field, and validated by means of a pre-existing traditional soil map of the area. The results revealed that the attributes derived from satellite image stood out from those derived from DEM in the prediction of soil groups. Based on the validation coefficients applied (overall accuracy, Kappa index, user’s accuracy and producer’s accuracy), the quality of the classification was satisfactory, despite the complexity of the environment.
Phylogeny and pathogenicity of Fusarium solani species complex (FSSC) associated with potato tubers
Authors: Gherbawy Youssuf A. , Hussein Mohamed A. , Hassany Nabila A. , Shebany Yassmin M. , Hassan Sabry , El-Dawy Eman G. A. 
Published: July 2022

Abstract
Potato (Solanum tuberosum L.) is among the top five crops growing worldwide following cereals, rice, wheat, barley and corn due to its high carbohydrate content and adaptability. Potatoes are particularly valued in developing countries as a rich source of vitamins C and B6, starch and essential amino acids. Fusarium solani species complex (FSSC) is a common pathogen of potato, causing dry rot in the Upper Egypt. In this study were isolated and identified FSSC from potato tubers based on the morphological followed by molecular characteristics. 187 isolates of Fusarium solani were achieved from infected and non-infected potato tubers gathered from different markets in the Upper Egypt. Dependent upon the morphological characteristics, sequence data from amplifying β-tubulin and specific translation elongation factor (TEF-1α) genes, all of the selected FSSC isolates were divided into three major groups (F. keratoplasticum, F. falciforme and F. solani). All the tested FSSC were capable of producing amylases. All of the isolates were examined for their pathogenic ability on healthy potato tubers, which showed pathogenic effects; with lesion sizes were quite variable. F. solani SVUFs73 showed a highly virulent effect.