bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing a critical social psychological perspective on women's leadership: A case illustration from the Global South
Authors: Nguyen Lan Thi , Taylor Greig , Gibson Paul , Gordon Raymond 
Published: March 2022

AbstractWhen applied to the Global South, mainstream positivist approaches to work and organisational psychology impose alien theories of personality (the self) and leadership. In the case of women, they fail to capture the richness of their experiences of life and leadership, which are influenced by the nexus between history, power and marginalisation—for many, even oppression. The purpose of this article is to demonstrate the value of a critical social psychological approach, despite its grounding in the Global North discourse, to analyse women's leadership from a cross‐cultural context. To illustrate, we provide an empirical example of a Vietnamese woman leader's life‐story drawing on the theoretical resources from critical social psychology to interpret her experiences. When viewed from this perspective, women's leadership is understood within a dialogical space, which is prior to and more fundamental than any instrumental reason and technical rationality. It is argued that this approach resists essentialising assumptions about gender and cultural practices of leadership, providing a more liberating means to understand the life and leadership of Vietnamese women. In the final analysis, we argue that this study contributes to the nascent field of critical work and organisational psychology.
Robot‐assisted laparoscopic abdominoperineal resection with en bloc prostatectomy using the Retzius‐sparing robot‐assisted radical prostatectomy technique
Authors: Takahashi Hiroki , Maeda Anri , Harata Shinnosuke , Watanabe Kaori , Yanagita Takeshi , Suzuki Takuya , Ushigome Hajime , Maeda Yuzo , Shiga Kazuyoshi , Ogawa Ryo , Matsuo Yoichi , Takiguchi Shuji 
Published: March 2022

AbstractIntroductionThe best surgical technique for rectal cancer invading the prostate remains controversial. Rectal resection with en bloc prostatectomy using a standard retropubic approach is an option but has disadvantages. We report a new surgical procedure applying Retzius‐sparing robot‐assisted radical prostatectomy.Materials and Surgical TechniqueFirst, the rectum was mobilized mainly at its dorsal side. Next, the prostate was separated from the bladder and urethra via the pouch of Douglas approach without opening the Retzius cavity, after which the surgical specimen was extracted through the perineal wound. Lateral pelvic lymph node dissection was performed after vesicourethral anastomosis.DiscussionThis new robotic procedure minimizes surgical trauma and preserves normal pelvic anatomy. Furthermore, this approach makes it easy to perform subsequent lateral pelvic lymph node dissection.
Effect of heat‐treated green tea waste feeding on fermentation kinetics, in vitro degradability, in vivo apparent digestibility, nitrogen balance, and blood metabolites in Black Bengal goat
Authors: Chowdhury Mohammed Rashed , Chanda Shuvashish , Shipa Aklima , Saiyara Tasfia , Chowdhury Zinat Jahan , Khan Mohammad Mehedi Hasan 
Published: March 2022

AbstractThe study was conducted to examine the effect of heat treatment of green tea waste (GTW) on rumen degradability, apparent digestibility, and plasma metabolites in Black Bengal goat based on in vitro and in vivo studies. The in vitro incubation was performed with autoclaved, oven, and freeze‐dried GTW, whereas animal study was conducted using 12 Black‐Bengal goats in a 3 × 3 Latin‐square design. Goats were fed a total‐mixed‐ration without (control) or with the partial replacement of soybean meal and barley with 50 g/kg dry matter (DM) of either oven‐dried or autoclaved GTW. Heat treatments reduced ether extract and tannins concentration but increased the effective DM and crude protein (CP) degradability of GTW. The highest values of in vitro volatile fatty acid concentration, molar proportion of propionate, ammonia‐nitrogen concentration, and cumulative gas production were observed for oven‐dried GTW among the tested GTW. Dietary treatment did not alter the DM intake, but apparent CP digestibility and retained nitrogen (N) were increased in goats fed control or oven‐dried GTW incorporated diets. Feeding autoclaved GTW diet increased the urinary and fecal N excretion in goats. In contrast, plasma glucose concentration was highest in goats fed control or oven‐dried GTW diet. In conclusion, oven drying could be a practical approach to increase protein digestibility and retained N in goats.
Immunophenotypically defined stem cell subsets in paediatric AML are highly heterogeneous and demonstrate differences in BCL‐2 expression by cytogenetic subgroups
Authors: Petersen Marianne A. , Rosenberg Carina A. , Brøndum Rasmus F. , Aggerholm Anni , Kjeldsen Eigil , Rahbek Ole , Ludvigsen Maja , Hasle Henrik , Roug Anne S. , Bill Marie 
Published: March 2022

AbstractIn adult acute myeloid leukaemia (AML), immunophenotypic differences enable discrimination of leukaemic stem cells (LSCs) from healthy haematopoietic stem cells (HSCs). However, immunophenotypic stem cell characteristics are less explored in paediatric AML. Employing a 15‐colour flow cytometry assay, we analysed the expression of eight aberrant surface markers together with BCL‐2 on CD34+CD38− bone marrow stem cells from 38 paediatric AML patients and seven non‐leukaemic, age‐matched controls. Furthermore, clonality was investigated by genetic analyses of sorted immunophenotypically abnormal stem cells from six patients. A total of 50 aberrant marker positive (non‐HSC‐like) subsets with 41 different immunophenotypic profiles were detected. CD123, CLEC12A, and IL1RAP were the most frequently expressed markers. IL1RAP, CD93, and CD25 expression were not restricted to stem cells harbouring leukaemia‐associated mutations. Differential BCL‐2 expression was found among defined cytogenetic subgroups. Interestingly, only immunophenotypically abnormal non‐HSC‐like subsets demonstrated BCL‐2 overexpression. Collectively, we observed pronounced immunophenotypic heterogeneity within the stem cell compartment of paediatric AML patients. Additionally, certain aberrant markers used in adults seemed to be ineligible for detection of leukaemia‐representing stem cells in paediatric patients implying that inference from adult studies must be done with caution.
Inhibition of sodium conductance by cannabigerol contributes to a reduction of dorsal root ganglion neuron excitability
Authors: Ghovanloo Mohammad‐Reza , Estacion Mark , Higerd‐Rusli Grant P. , Zhao Peng , Dib‐Hajj Sulayman , Waxman Stephen G. 
Published: March 2022

Background and PurposeCannabigerol (CBG), a non‐psychotropic phytocannabinoid and a precursor of ∆9‐tetrahydrocannabinol and cannabidiol, has been suggested to act as an analgesic. A previous study reported that CBG (10 μM) blocks voltage‐gated sodium (Nav) currents in CNS neurons, although the underlying mechanism is not well understood. Genetic and functional studies have validated Nav1.7 channels as an opportune target for analgesic drug development. The effects of CBG on Nav1.7 channels, which may contribute to its analgesic properties, have not been previously investigated.Experimental ApproachTo determine the effects of CBG on Nav channels, we used stably transfected HEK cells and primary dorsal root ganglion (DRG) neurons to characterize compound effects using experimental and computational techniques. These included patch‐clamp, multielectrode array, and action potential modelling.Key ResultsCBG is a ~10‐fold state‐dependent Nav channel inhibitor (KI‐KR: ~2–20 μM) with an average Hill‐slope of ~2. We determined that, at lower concentrations, CBG predominantly blocks sodium Gmax and slows recovery from inactivation. However, as the concentration is increased, CBG also induces a hyperpolarizing shift in the half‐voltage of inactivation. Our modelling and multielectrode array recordings suggest that CBG attenuates DRG excitability.Conclusions and ImplicationsInhibition of Nav1.7 channels in DRG neurons may underlie CBG‐induced neuronal hypoexcitability. As most Nav1.7 channels are inactivated at the resting membrane potential of DRG neurons, they are more likely to be inhibited by lower CBG concentrations, suggesting functional selectivity against Nav1.7 channels, compared with other Nav channels (via Gmax block).
Comparative validity between the Canadian and the Dutch norms of the Alberta Infant Motor Scale in a preterm population
Authors: Gautier Clara , Alexandre Marie , Zaczek Sophie , Mostaert Anne , Legros Ludovic 
Published: March 2022

AbstractBackgroundPrematurity remains a leading cause of motor developmental delays. The Alberta Infant Motor Scales (AIMS) is a useful tool to easily assess motor development. However, during the last decade, cross‐cultural differences have been identified regarding the original AIMS norms. Therefore, the aim of this study is twofold: confirm the validity of the AIMS in a preterm population and compare the new Dutch AIMS norms to the original Canadian ones in our Belgian population.MethodNinety‐six preterm infants were assessed simultaneously on the AIMS and on the Bayley Scales of Infant‐Toddler Development (Bayley‐III) at age 9–14 months. Concurrent validity was evaluated by correlation analysis. Among these, 89 were assessed on the AIMS at age 3–6 months. Clinimetric properties of both AIMS norms were calculated to compare their ability to detect a motor delay on the Bayley‐III at age 9–14 months.ResultPearson's coefficient showed an excellent level of correlation between the two scales (r = 0.91). At age 3–6 months, only the 10th Canadian centile showed acceptable properties to predict a significant motor delay. At age 9–14 months, the 5th centile of both norms showed good properties to diagnose a significant motor delay, while only the Canadian norms seems to be sensitive enough to diagnose a mild motor delay.ConclusionThe new Dutch norms seem to be less sensitive but more specific than the Canadian ones and therefore require adapted cut‐offs to diagnose motor developmental delays in a preterm population.
A flexural exanthem following postexposure prophylaxis
Authors: Roche Darren , Murray Gregg , Hackett Catriona , Tobin Anne-Marie 
Published: March 2022

Abstract
We report a case of symmetrical drug-related intertriginous and flexural exanthema following antiretroviral postexposure prophylactic medications, tenofovir and emtricitabine, commencement of which preceded the onset of the rash. Tenofovir and emtricitabine are both nucleoside reverse transcriptase inhibitor medications, commonly used to prevent development of AIDS.
The use of the faecal immunochemical test during the COVID‐19 pandemic to triage urgent colorectal cancer referrals
Authors: Kamel Faddy , Zulfiqar Saadia , Penfold WIlliam , Weatherell Stephanie , Madani Rana , Nisar Pasha , Bearn Philip 
Published: March 2022

AbstractAimDuring the first wave of the COVID‐19 pandemic in 2020, elective gastrointestinal endoscopy services were abbreviated for fear of viral transmission. However, urgent suspected colorectal cancer (CRC) referrals continued. Serendipitously, a national study suggested that a new faecal immunochemical test (FIT) might be helpful in triaging patients with colorectal alarm symptoms.MethodsThis was a single centre observational study of patients referred using NG12 criteria between March and August 2020. Patients were triaged to the urgent cancer pathway for FIT ≥ 10 μg/g and investigated using the latest National Health Service England guidance. Demographic data, method of investigations, cancer and polyp detection rates were compared to patients referred in the 6 months prior to the use of FIT as a triage tool.ResultsIn all, 1192 patients (median age 70) were referred using NG12 guidelines during the pandemic period, compared with 1592 patients (median age 72) in the previous 6 months. CRC detection was similar in both groups (n = 45, 2.8% vs. n = 38, 3.5%; P = 0.248). Two patients with a negative FIT (0.36%) had CRC. Using FIT as a triage tool resulted in a significant reduction in the use of endoscopy (n = 477, 43.6% vs. n = 1186, 74.5%; P > 0.001) with a significant increase in CT scanning (n = 696, 63.6% vs. n = 750, 47.1%; P < 0.001).ConclusionThe use of FIT in NG12 patients triaged during the first wave of the COVID‐19 pandemic reduced endoscopy but not CT scanning and did not compromise CRC detection rates. It is a safe method that aids in reducing the burden on services greatly. A negative FIT test does not absolutely exclude CRC.
Does multimodal perioperative pain management enhance immediate and short‐term outcomes after living donor partial hepatectomy? A systematic review of the literature and expert panel recommendations
Authors: Hogan Brian J , Pai Sher‐Lu , Planinsic Raymond , Suh Kyung‐Suk , Hillingso Jens G , Ghani Shahi Abdul , Fan Ka Siu , Spiro Michael , Raptis Dimitri Aristotle , Vohra Vijay , Auzinger Georg ,   the ERAS4OLT.org Working Group
Published: March 2022

AbstractBackgroundThe optimal analgesic strategy for patients undergoing donor hepatectomy is not known and the potential short‐ and long‐term physical and psychological consequences of complications are significant.ObjectivesTo identify whether a multimodal approach to pain of the donor intraoperatively enhances immediate and short‐term outcomes after living liver donation, and to provide international expert panel recommendations.Data sourcesOvid MEDLINE, Embase, Scopus, Google Scholar, and Cochrane Central.MethodsSystematic review following PRISMA guidelines and recommendations using the GRADE approach derived from an international expert panel. PROSPERO 2021 CRD42021260699.ResultsNine studies assessing multi‐modal analgesia strategies were included in a qualitative assessment. Interventions included local, regional, and neuro‐axial anesthetic techniques, pharmacological intervention (NSAIDs, COX‐2 inhibitors, ketamine, dexmedetomidine, and lidocaine), and acupuncture. Overall, there was a significant (40%) reduction in opioid requirement on day 1 and a significant reduction in pain scores in the intervention vs control groups. Significant reductions in either length of stay or post‐operative complications were demonstrated in four of nine studies.ConclusionsOpioid use for patients undergoing donor hepatectomy is likely to impact both their short‐ and long‐term outcomes. To reduce post‐operative pain scores, shorten length of hospital stay, and promote earlier post‐operative return of bowel function, we recommend that multi‐modal analgesia be offered to patients undergoing living donor hepatectomy. Further research is required to confirm which multi‐modal techniques are most associated with enhanced recovery in living liver donors.
Chinese Traditional Bioethics
Authors: Li Yingying , Cui Huaqian , Li Enchang 
Published: March 2022

AbstractChinese traditional bioethics is based on the life origin theory of “Qi (vital force) permeates everything under heaven”, the attitude towards life theory of “loving people” and “loving things”, and the life transcendence theory of “eternity” and “immortality”. The life origin theory answers the question of how life comes into being, which is the basis for exploring the mystery of life. The attitude towards life theory gives answers to the question of how to treat life properly and establishes the basic requirements and criteria for treating life. The life transcendence theory responds to the question of how to make life more meaningful. Those three thoughts support each other and explain each other with the inner logical band between these three basic thoughts, and tentatively offers a reasonable way for the reconstruction of traditional Chinese bioethics, which can be a special theoretical resource for today's bioethical research.
Posterior cortical atrophy: Primary occipital variant
Authors: Shir Dror , Graff‐Radford Jonathan , Machulda Mary M. , Pham Nha Trang Thu , Jack Clifford R. , Lowe Val J. , Whitwell Jennifer L. , Josephs Keith A. 
Published: March 2022

AbstractBackgroundPosterior cortical atrophy (PCA) is one of the atypical Alzheimer's disease variants, characterized by predominant visuospatial and visuoperceptual deficits, with established dorsal and ventral subtypes. A third primary occipital (caudal) variant has been suggested. We aimed to determine its demographics, clinical manifestations, and biomarker findings.MethodsFifty‐two PCA patients were investigated. Patients underwent neuropsychological assessment, magnetic resonance imaging, and fluorodeoxyglucose (FDG)‐, amyloid‐, and tau‐positron emission tomography (tau‐PET) scans. Normalized regional FDG‐PET values were represented as z‐scores relative to a control population. Patients were divided into “primary occipital” and “other PCA” subgroups according to FDG‐PET‐defined criteria, with primary occipital defined as patients in which the z‐scores for occipital subregions were at least one standard deviation lower (SD) (i.e., more abnormal) than the z‐scores in all other brain regions. Global amyloid‐PET, temporo‐parietal FDG‐PET, and temporal tau‐PET regions‐of‐interest (ROIs) were calculated.ResultsNine patients were classified as primary occipital; they were older (p = 0.034) and had more years of education (p = 0.007) than other PCA patients. The primary occipital group performed worse on the Ishihara test for color perception (p < 0.001), while other PCA patients performed worse on the Western Aphasia Battery (WAB) praxis scale (p = 0.005). Overall neuropsychiatric symptom burden was lower in the primary occipital group (p < 0.001). The FDG‐PET meta‐ROI was higher in the primary occipital subtype (p = 0.006), but no differences were observed in amyloid‐ and tau‐PET.ConclusionsOur findings suggest that primary occipital PCA is characterized by an older age at onset, more color perception dysfunction, less severe ideomotor apraxia, and less hypometabolism in temporo‐parietal meta‐ROI compared to established phenotypes.
Relation of sensorimotor and cognitive cerebellum functional connectivity with brain structural damage in patients with multiple sclerosis and no disability
Authors: Tommasin Silvia , Iakovleva Viktoriia , Rocca Maria Assunta , Giannì Costanza , Tedeschi Gioacchino , De Stefano Nicola , Pozzilli Carlo , Filippi Massimo , Pantano Patrizia ,   the INNI Network
Published: March 2022

AbstractBackground and purposeTo investigate the relationship between the functional connectivity (FC) of the sensorimotor and cognitive cerebellum and measures of structural damage in patients with multiple sclerosis (MS) and no physical disability.MethodsWe selected 144 relapsing–remitting MS patients with an Expanded Disability Status Scale score of ≤1.5 and 98 healthy controls from the Italian Neuroimaging Network Initiative database. From multimodal 3T magnetic resonance imaging (MRI), including functional MRI at rest, we calculated lesion load, cortical thickness, and white matter, cortical gray matter, and caudate, putamen, thalamic, and cerebellar volumes. Voxel‐wise FC of the sensorimotor and cognitive cerebellum was assessed with seed‐based analysis, and multiple regression analysis was used to evaluate the relationship between FC and structural damage.ResultsWhole brain, white matter, caudate, putamen, and thalamic volumes were reduced in patients compared to controls, whereas cortical gray matter was not significantly different in patients versus controls. Both the sensorimotor and cognitive cerebellum showed a widespread pattern of increased and decreased FC that were negatively associated with structural measures, indicating that the lower the FC, the greater the tissue loss. Lastly, among multiple structural measures, cortical gray matter and white matter volumes were the best predictors of cerebellar FC alterations.ConclusionsIncreased and decreased cerebellar FC with several brain areas coexist in MS patients with no disability. Our data suggest that white matter loss hampers FC, whereas, in the absence of atrophy, cortical volume represents the framework for FC to increase.
Development of a force field for modeling lithium borosilicate glasses
Authors: Urata Shingo , Miyajima Tatsuya , Kayaba Noriyoshi , Deng Lu , Du Jincheng 
Published: March 2022

AbstractA force field (FF) with a Buckingham function was developed for modeling lithium borosilicate (LBS) glasses using molecular dynamics (MD) simulations. The parameter set of the FF for two‐body interaction between Li and O (Li–O) was optimized to reproduce both theoretically calculated force and energy using the density functional theory (DFT) and experimental properties, such as density and mechanical moduli. Bayesian optimization based on a machine‐learning technique was employed to efficiently find the best parameter set in a wide parameter space. The accuracy of the MD simulation using the optimized FF of Li–O together with the previously reported FFs for Si–O, B–O, and O–O pairs was examined by comparing with experimentally measured boron coordination numbers () in a variety of LBS glasses. Consequently, it was found that the combination of the FFs is not accurate enough to reproduce the boron coordination change with varying glass compositions. Therefore, the parameter set of the B–O pair was extended to be composition‐dependent to reproduce the experimental data on the N. It was confirmed that the empirical parameter correction as a function of [SiO]/[BO] and [LiO]/[BO] ratios enables modeling LBS glass consistently with experimental NMR data.
Corporate tax behavior and political uncertainty: Evidence from national elections around the world
Authors: Li Qingyuan , Maydew Edward L. , Willis Richard H. , Xu Li 
Published: March 2022

AbstractWe construct a sample of firms in 36 countries with 158 elections to examine corporate tax behavior in the face of political uncertainty. We define political uncertainty as unmeasurable unpredictability regarding governmental policies or regulatory shifts, such as tax rates, tax enforcement and general economic conditions, emanating from a possible change in political leadership. If insufficient information exists to develop plausible expectations about future tax‐related outcomes, ambiguity‐averse managers will attend to relatively more pessimistic priors and assume the worst‐case scenario. We expect firms to increase tax avoidance in election years given uncertainty regarding the post‐election tax and macroeconomic environment. Our results are consistent with this argument. Firms increase their corporate tax avoidance in election years, consistent with managers exercising current tax planning strategies while it is still most optimal to do so given post‐election uncertainty. The effect is increasing in the political uncertainty associated with the election. Specifically, for elections that are closely contested, representing uncertainty regarding the victor, or held in countries with fewer electoral checks and balances, representing uncertainty regarding the ease of effectuating potential post‐election changes. We document increased reshuffling of tax burdens across firms after elections, further supporting that elections reflect periods of heightened tax uncertainty.