bluuebunny/crossref_metadata_2025_split huggingface dataset:
GAMBARAN HEALTH SEEKING BEHAVIOR PENDERITA HIPERTENSI DI MASA PANDEMI COVID-19
Authors: Salasi Arisa , Deli Hellena , Amir Yufitriana 
Published: February 2022

Pendahuluan: Health seeking behavior merupakan perilaku yang dilakukan oleh orang yang menderita suatu penyakit untuk memperoleh kesembuhan. Penelitian ini bertujuan untuk mengetahui gambaran health seeking behavior penderita hipertensi di masa pandemi COVID-19.
Metode: Penelitian ini menggunakan desain penelitian deskriptif dengan jumlah sampel sebanyak 70 responden. Alat ukur yang digunakan adalah kuesioner. Penelitian ini dilakukan pada tanggal 17-27 Juli 2021 di Puskesmas Rejosari. Analisa yang digunakan dalam penelitian ini adalah analisis statistik deskriptif.
Hasil: Perilaku pencarian pengobatan penderita hipertensi di masa pandemi COVID-19 berdasarkan usia lebih banyak memilih melakukan pengobatan ke public medicine. Responden dengan pendidikan SMA memilih public medicine (60,9%), responden dengan penghasilan < Rp 2.998.000 memilih public medicine (48,9%), dan responden yang telah menderita hipertensi selama ≤ 5 tahun memilih public medicine (45,2%).
Kesimpulan: Perilaku pencarian pengobatan penderita hipertensi di masa pandemi COVID-19 dari segala kategori mayoritas responden memilih melakukan pengobatan ke public medicine.
Kata Kunci : COVID-19; Health Seeking Behavior; Hipertensi

Introduction: Health seeking behavior is behavior carried out by people who suffer from a disease to obtain healing. This study aims to describe the health seeking behavior of hypertension sufferers during the COVID-19 pandemic.
Methods : This study used a research design descriptive with a sample of 70 respondents with hypertension who met the inclusion criteria. The measuring instrument used is a questionnaire. This research was conducted on 17-27 July 2021 at the Puskesmas Rejosari. This study uses descriptive statistical analysis.
Results:The behavior of seeking treatment for hypertension sufferers during the COVID-19 pandemic based on age is more likely to choose treatment public medicine for. Respondents with high school education chose public medicine (60.9%), respondents with income <Rp 2,998,000 chose public medicine (48.9%), and respondents who had suffered from hypertension for 5 years chose public medicine (45.2% ).
Conclusion: The behavior of seeking treatment for hypertension sufferers during the COVID-19 pandemic from all categories, the majority of respondents chose to go to treatment public medicine for.

Keywords : COVID-19; Health Seeking Behavior; Hypertension
VERBAL AND NONVERBAL ASPECTS IN REALIZING LANGUAGE POLITENESS IN THE FILM “SABTU BERSAMA BAPAK” MADE BY ADHITYA MULYA
Authors: Deasy Wahyu Hidayati  , Prima Gusti Yanti  , Nini Ibrahim  
Published: February 2022

This study aims to describe the verbal and nonverbal aspects of the Realization of Language Politeness in the film "SabtubersamaBapak" by Adhitya Mulya and it was designed by using a qualitative descriptive method with content analysis techniques. This qualitative descriptive method is used to collect and compile data, analyze and interpret data (Rukajat, 2018). By using a qualitative descriptive method, the researcher simply analyzed data based on verbal and nonverbal language politeness in the film "SabtubersamaBapak" by AdhityaMulya. The results showed that the most dominant language politeness in verbal communication appears in the film the film "Sabtu bersama Bapak" are sympathy and wisdom. Meanwhile, language politeness in non-verbal communication is dominant in kinesics, namely gestures, hands, head, and so on.
PENGARUH PAJAK PENGHASILAN BADAN, CURRENT RATIO DAN KINERJA PERUSAHAAN TERHADAP RETURN ON ASSET PADA PERUSAHAAN JENIS CONSUMMER GOODS YANG TERDAFTAR DI BEI PERIODE 2018-2021
Authors: SAHRUL IHSAN  
Published: February 2022

This study aims to determine the effect of corporate income tax, current ratio, and company performance on return on assets in consumer goods industrial companies listed on the Indonesian stock exchange for the 2018-2021 period. This study is a quantitative study using secondary data in the form of company financial statements. which are listed on the Indonesia stock exchange for the period 2018-2021. The determination of the sample in this study uses purposive sampling. Data analysis used classical assumption tests and multiple linear analyses.
The independent variables used in this study are corporate income tax (X1), current ratio (X2), and company performance (X3), while the dependent variable is the return on assets (Y). The results showed that there was a simultaneous negative but significant effect of corporate income tax, current ratio and company performance on return on assets in consumer goods companies listed on the Indonesian stock exchange. And there is a positive and partially significant effect on the company's performance on return on assets, while corporate income tax and the current ratio have no partial significant effect on return on assets in consumer goods companies listed on the Indonesian stock exchange for the 2018-2021 period.
Abstrak

Penelitian ini bertujuan untuk mengetahui pengaruh antara pajak penghasilan badan , current ratio dan kinerja perusahaan terhadap return on asset pada perusahaan industri jenis consummer goods yang terdaftar di bursa efek Indonesia periode 2018-2021.Penelitian ini merupakan penelitian kuantitatif dengan menggunakan data sekunder berupa laporan keuangan perusahaan yang terdaftar di bursa efek Indonesia periode 2018-2021.Penentuan sampel dalam penelitian ini menggunakan purposive sampling.Analis data yang digunakan uji asumsi klasik dan analisis linier berganda.
Variabel independen yang digunakan dalam penelitian ini adalah pajak penghasilan badan (X1), current ratio (X2) dan kinerja perusahaan (X3), sedangkan variabel dependen return on asset (Y). Hasil penelitian menunjukkan bahwa ada pengaruh negative tetapi signifikan secara simultan dari pajak penghasilan badan, curreent ratio dan kinerja perusahaan terhadap return on asset pada perusahaan jenis consummer goods yang terdaftar di bursa efek indonesia. Dan ada pengaruh positif dan signifikan secara parsial kinerja perusahaan terhadap return on asset, sedangkan pajak penghasilan badan dan current ratio tidak berpengaruh signifikan secara parsial terhadap return on asset pada perusahaan jenis consummer goods yang terdaftar di bursa efek Indonesia periode 2018-2021
Dinâmica de sistemas auxiliando na identificação de fatores que podem influenciar em atrasos de entregas e projetos em um instituto de inovação
Authors: Everton Michels  , Fernando Antonio Fornellini  
Published: February 2022

Diversos estudos já abordaram o ciclo de retrabalho em dinâmica de sistemas no que tange o gerenciamento de projetos. No entanto, mesmo este servindo para a grande maioria dos casos, algumas especificidades derivam deste modelo, principalmente pelo contexto avaliado. Com base nisso, e diante da dificuldade de gerenciar projetos de inovação, com altos riscos devido ao grau de incertezas, e sofrendo com atraso em entregas e no projeto, este estudo visa identificar quais a variáveis que mais ou menos influenciam nos projetos de inovação do Instituto Senai de Inovação de Sistemas Embarcados. Para tal, foi feito uma revisão tradicional somada a um estudo bibliométrico a fim de embasar este trabalho, junto a um estudo empírico utilizando dinâmica de sistemas, que resultou na identificação das principais variáveis que afetam o sistema de gestão dos projetos do instituto em questão, além de verificar que o mesmo amplia o conhecimento sobre dinâmica de sistemas em projetos e introduz novas variáveis as quais ainda há pouca abordagem.

Several studies have addressed the rework cycle in system dynamics with regard to project management. However, even though it can be used in most cases, some specificities derive from this model, mainly due to the evaluated context. Based on this, and facing the difficulty of managing innovation projects, with high risks due to the degree of uncertainties, and suffering with delays in deliveries and in the project, this study aims to identify which variables have more or less influence in the innovation projects of the Senai Institute for Innovation in Embedded Systems. To this end, a traditional review was done together with a bibliometric study in order to base this work, together with an empirical study using system dynamics, which resulted in the identification of the main variables that affect the project management system of the institute in question, besides verifying that it expands the knowledge about system dynamics in projects and introduces new variables which there is still little approach.
Studi tentang Perilaku Perundungan Siswa Sekolah Menengah Kejuruan (SMK) di Kabupaten Bima
Authors: Chiani Saraswati Haylian , Sulami Neti , Windari Arindiah Puspo , Irawan Bambang , Indrayani Novi 
Published: February 2022

Penelitian ini adalah penelitian kualitatif ditujukan untuk memahami fenomena-fenomena sosial dari sudut pandang partisipan sementara itu subyek dalam penelitian ini adalah guru bimbingan konseling, siswa-siswi yang terkait perihal perilaku perundungan disekolah, remaja (siswa SMA kelas 10, 11 dan 12). Lokasi yang diambil dalam penelitian ini adalah sekolah Sekolah Menengah Kejuruan baik Negeri dan Swasta di Kabupaten Bima yaitu SMKN 2 Soromandi dan SMK Kasman Bima, hasil dari penelitian ini diketahui bahwa tindakan perundungan di sekolah dimulai dari sekolah dasar dimana siswa yang melakukan perundungan merupakan korban perundungan juga sehingga hal tersebut terbawa sampai seterusnya dan dianggap hal yang normal dan dikarenakan adanya faktor keluarga yang disebabkan oleh kurangnya kasih sayang orang tua dan kurangnya perhatian yang diberikan oleh orang tua kepada siswa disebabkan mayoritas orang tua siswa adalah petani yang lebih banyak yang normal dan dikarenakan adanya faktor keluarga yang disebabkan oleh kurangnya kasih sayang orang tua dan kurangnya perhatian yang diberikan oleh orang tua kepada siswa disebabkan mayoritas orang tua siswa adalah petani yang lebih banyak menghabiskan waktu di lading dan sawah sehingga tidak ada kontrol dan bimbingan kepada anak. Selain itu, tindakan perundungan yang dilakukan siswa kepada siswa lain lebih banyak adalah perundungan secara verbal yaitu saling mengolok atau mengejek nama orang tua yang dimana hal tersebut kurang mendapatkan atensi dari pihak guru dan sekolah serta sekolah hanya fokus pada tahap penyelesaian masalah tanpa melakukan pendampingan lebih lanjut terhadap siswa yang dirundung dengan melihat kondisi psikologis anak.
“Habrá viejo mas morlaco? Vayase á tomar tabaco”. Moral y medicina: conceptos y usos (siglos XVII-XVIII)
Authors: Figueiroa Rego Joao 
Published: February 2022

La proliferación del uso de tabaco a lo largo de los siglos XVII y XVIII, ha generado un conjunto de trabajos literarios en los que se mezclan conceptos morales y normas médicas. Algunos de esos textos nos hacen sonreír ante la ingenuidad e ignorancia de una realidad cuyas consecuencias aún eran poco conocidas. Si para algunos, el consumo de tabaco era inmoral y dañino, por lo tanto, demonizado, para otros autores sería no un vicio pero un recurso que podía contribuir con éxito para el tratamiento de enfermedades.
Nuevos canales de comunicación institucional en materia de seguridad
Authors: Bordonado Bermejo María Julia , Jaspe Nieto Javier 
Published: February 2022

Objetivo: Análisis de las acciones de comunicación institucional llevadas a cabo por la Guardia Civil en la red social TikTok.
Diseño/metodología/enfoque: Estudio cuantitativo a efectos de la medición del impacto de dichas acciones de comunicación. Posteriormente, la investigación aborda los problemas jurídicos y el debate ético en torno al alcance de los objetivos planteados en la política de comunicación de la Guardia Civil respecto a su actividad en TikTok, partiendo de un análisis crítico de estas dimensiones del fenómeno.
Limitaciones/implicaciones: La utilidad del trabajo reside en el mejor entendimiento de la pertinencia de la citada política de comunicación con arreglo a su validez jurídica y deontológica y el cumplimiento de una serie de objetivos estratégicos.
Originalidad/contribución: La investigación se ocupa de una práctica institucional novedosa y poco estudiada en el ámbito de la comunicación de defensa y seguridad, con importantes implicaciones para la reputación corporativa de las fuerzas y cuerpos de seguridad del Estado.
In leukemia, knock-down of the death inducer-obliterator gene would inhibit the proliferation of endothelial cells by inhibiting the expression of CDK6 and CCND1
Authors: Cao Honghua , Wang Lilan , Geng Chengkui , Yang Man , Mao Wenwen , Yang Linlin , Ma Yin , He Ming , Zhou Yeying , Liu Lianqing , Hu Xuejiao , Yu Jingxing , Shen Xiufen , Gu Xuezhong , Yin Liefen , Shen Zhenglei 
Published: February 2022

Background
Endothelial cells (ECs) are a critical component of the hematopoietic niche, and the cross-talk between ECs and leukemia was reported recently. This study aimed to determine the genes involved in the proliferation inhibition of endothelial cells in leukemia.

Methods
Human umbilical vein endothelial cells (HUVEC) were cultured alone or co-cultured with K562 cell lines. GeneChip assays were performed to identify the differentially expressed genes. The Celigo, MTT assay, and flow cytometric analysis were used to determine the effect of RNAi DIDO on cell growth and apoptosis. The differently expressed genes were verified by qRT-PCR (quantitative real-time PCR) and western-blot.

Results
In K562-HUVEC co-cultured cell lines, 323 down-regulated probes were identified and the extracellular signal-regulated kinase 5 (ERK5) signaling pathway was significantly inhibited. Among the down-regulated genes, the death inducer-obliterator gene (DIDO) is a part of the centrosome protein and may be involved in cell mitosis. As shown in the public data, leukemia patients with lower expression of DIDO showed a better overall survival (OS). The HUVEC cells were infected with shDIDO lentivirus, and reduced expression, inhibited proliferation, and increased apoptosis was observed in shDIDO cells. In addition, the expression of Cyclin-Dependent Kinase 6 (CDK6) and Cyclin D1 (CCND1) genes was inhibited in shDIDO cells. Finally, the public ChIP-seq data were used to analyze the regulators that bind with DIDO, and the H3K4me3 and PolII (RNA polymerase II) signals were found near the Exon1 and exon2 sites of DIDO.

Conclusion
The knock-down of DIDO will inhibit the proliferation of endothelial cells in the leukemia environment. The expression of DIDO may be regulated by H3K4me3 and the inhibition of DIDO may lead to the down-regulation of CDK6 and CCND1. However, how DIDO interacts with CDK6 and CCND1 requires further study.
A revision ofPlectanocotyle(Monogenea, Plectanocotylidae), with molecular barcoding of three species and the description of a new species from the streaked gurnardChelidonichthys lastovizaoff Algeria
Authors: Ayadi Zouhour El Mouna , Tazerouti Fadila , Gey Delphine , Justine Jean-Lou 
Published: February 2022

BackgroundThe family Plectanocotylidae includes parasites of the gills of marine fish; although nine genera and about 20 species have been described, almost no molecular information is available. Putting asidePlectanocotyle ellipticaDiesing, 1850, supposedly a parasite of the white perchMorone americana, never found again since its original description, two species were valid withinPlectanocotyleDiesing, 1850 before this work:Plectanocotyle gurnardi(Van Beneden & Hesse, 1863) Llewellyn, 1941 andPlectanocotyle majorBoudaya, Neifar & Euzet, 2006.MethodsIn this paper, we describe the third species of the genusPlectanocotyleand perform a comparative morphological and molecular analysis of the three species and ofTriglicola obscura(Euzet & Suriano, 1974) Mamaev, 1976. Host fishes were also barcoded (COI) for confirmation of host identifications.ResultsPlectanocotyle lastovizaen. sp. is described from the gills of the streaked gurnardChelidonichthys lastovizacollected off Algeria. The species is compared with specimens ofPlectanocotylecf.gurnardi(fromC. lastoviza) from the same locality andP. majorandT. obscura(both from the longfin gurnardC. obscurus). Molecules fromPlectanocotylecf.gurnardicould not be compared withP. gurnardifrom the type-host and type-locality and we kept the status of the Mediterranean specimens as pending. Algeria is a new geographic record forP. majorandT. obscura.Plectanocotyle lastovizaen. sp. is distinguished from the other species found in the Mediterranean by the measurements of clamps, number of testes, and COI sequences, with notable divergence (7.8–11.8%) from the other two species of the genus.DiscussionWe briefly present a list of currently known members of the family Plectanocotylidae, their biology and their hosts.
Effect of Cigarette Smoking on Location of Infarction in Patients Presented with ST-Segment Elevation Myocardial Infarction
Authors: Sherrah Ahmed Mohammed , Ahmed Elshekh Ayman , Abd El-Al Mohamed Ahmed , Elsayed Elsetiha Mohamed 
Published: February 2022

Background: In an acute ST-elevation myocardial infarction, transmural myocardial ischemia causes myocardial damage or necrosis (STEMI). In order to establish myocardial ischemia damage, the current clinical definition of myocardial infarction (MI) in 2018 includes abnormal cardiac biomarkers. STEMI is linked to a greater risk of mortality in the hospital compared to non-ST segment elevation acute coronary syndromes. The study's purpose was to investigate and assess the effect of cigarette smoking on the location of infarction in people who had ST-segment elevation myocardial infarction.
Methods: The present case-control research investigated 100 individuals who had a first ST segment elevation acute myocardial infarction and got split into two groups based on the smoking status: group 1 (50 patients): Group 1 (50 patients) were smokers, whereas group 2 (50 patients) were nonsmokers.
Results: Smokers were significantly younger than non-smokers (53.86±7.77) years vs. (58.20 ± 7.80), P = 0. 006. Gender distribution: Smokers were significantly more likely to be male (82.0% vs. 58.0%, P = 0.009). inferior STEMI was statistically significant difference among the two groups (P value =0.045*). Myocardial Infarction Localization by electrocardiogram was statistically significant different among the two groups (P value =0.045*). Ejection fraction (EF) was statistically significant different among the two groups (smoker and nonsmokers respectively 54.86 ± 8.58% vs. 49.04 ± 6.61%) (P value =0.001*).
Conclusions: Smoking raises STEMI risk, and smokers are more likely than non-smokers to develop coronary artery disease at an earlier age.
Determination of Yearly Performance and Degradation Rate of Electrical Parameters of a Monocrystalline Photovoltaic Modules in Minna, Central Nigeria
Authors: Olakanmi Alilu, Saliu , Joel Ezenwora , Abiodun Stephen Moses , Ibrahim Aku , Samuel Matthew , Aliyu Ahmadu 
Published: February 2022

Outdoor degradation analysis was carried out on a monocrystalline PV module rated 10 W using the CR1000 software-based Data Acquisition System (DAS). The PV module under test and meteorological Sensors were installed on a metal support structure on the same test plane. The data obtained was monitored from 09:00 to 18:00 hours each day continuously for a period of four years, from December 2014 to November 2018.The experiment was carried out near the Physics Department, Federal University of Technology, Minna (latitude 09o37'N, longitude 06o32'E, and 249 meters above sea level). The sensors were connected directly to the CR1000 Campbell Scientific data logger, while the module is connected to the logger via electronic loads. The logger was programmed to scan the load current from 0 to 1 A at intervals of 50mA every 5 minutes, and average values of short-circuit current, (Isc,) open-circuit voltage, (Voc), current at maximum power, (Imax), the voltage at maximum power,(Vmax), power and maximum power obtained from the modules together with the ambient parameters are recorded and logged. Data download at the data acquisition site was performed every 7 days to ensure effective and close monitoring of the data acquisition system (DAS). At the end of each month and where necessary, hourly, daily and monthly averages of each of the parameters-solar irradiance, solar insolation, wind speed, ambient and module temperatures, and the output response variables (open-circuit voltage, Voc, short-circuit current, Isc, the voltage at maximum power, Vmax, current at maximum power, Imax, efficiency, Eff, and fill factor, FF) of the photovoltaic modules were obtained.Yearly averages of the performance variables were obtained to ascertain the performance, degradation rate, and lifespan of the module. The module performance for the four years of study was compared with Standard Test Condition (STC) specifications. The maximum power achieved at 1000W/m2 for the four years of study are 0.711W, 1.82W, 0.50W, and 0.22W representing 7.11%, 18.39%, 5.0% and 2.25% of the manufacturer’s 10W specification. Module efficiency at 1000W/m2 for the four years of study is 3.30%, 10.12%, 3.98%, and 2.82% respectively as against the manufacturer's STC specification of 46%. Accordingly, Module Performance Ratios for the PV module investigated were 0.072, 0.22, 0.087, and 0.061respectively. For the Rate of Degradation (RoD), it was observed that Open-Circuit voltage (Voc), Short-Circuit Current (Isc), Power-Output (P), and Maximum Power (Pmax), has an average yearly degradation rate of 1.06V, 0.002A, 0.082W and 0.142W representing 4.9%,0.30%,0.56%, and 1.4%respectively for the four years of study.
Role of Antioxidants by Comparative Evaluation of Oxidative Stress in Heterozygous v/s Homozygous Sickle Cell Disease Patients: Research Protocol
Authors: Wasnik Rina Raibhan , Akarte Nilkanth Ramji , Dhok Archana , Anjankar Ashish P. 
Published: February 2022

Background: Red blood cells are sources for oxidants in Sickle cell anaemia, a genetic disorder of itself. Heme iron and oxygen in oxygenated hemoglobin have bonding interaction and association with electron transfer. In response, antioxidant has modus operandi to reduce oxidative stress and damage to RBC and tissue.
The studies on biochemical indicators for oxidative stress in sickle cell would further enhance the understanding and present knowledge of effects of antioxidants on the status of iron metabolism and consequent relief to the sickle cell anaemia patients.
Objectives: To evaluate oxidative stress and Antioxidant levels and iron indices factors in heterozygous and homozygous sickle cell disease patients and compare between them along with normal healthy control and Iron Deficiency anaemia
Methodology: Comparative Cross-Sectional Study is designed to explore specific antioxidant levels and oxidative stress along with Iron Indices among sickle cell anaemia diagnosed cases attending/admitted in the department of Medicine, Paediatrics and Community Medicine at Jawaharlal Nehru Medical College and its Hospital, Sawangi, Meghe, along with age and sex matched healthy individuals from general population.
Results: Oxidative stress as evaluated by stress markers may be higher among the Homozygous sickle cell disease than among the Heterozygous.
Conclusion: Oxidative stress may be compounded in sickle cell diseases patients in conjugation with iron deficiency.