bluuebunny/crossref_metadata_2025_split huggingface dataset:
Projeto e implementação de assistente pessoal para agendamento de compromissos
Authors: Vendramini Mateus Ramos , Imagure Ricardo Ciriaco Camargo , Barretto Marcos Ribeiro Pereira 
Published: June 2022

O processo de agendamento de compromissos envolve a condução de uma negociação entre duas ou mais pessoas e pode ser um processo tedioso para muitos, que leva a resultados não ótimos no agendamento devido à falta de comprometimento das pessoas à tarefa de negociação (tanto em ambientes profissionais como pessoais de cada um). Para resolver esse problema, foi proposta a implementação de um assistente com uma arquitetura dividida em dois grandes módulos: Semantizador, responsável por fazer o processamento de linguagem natural e criar um objeto com uma semântica que é utilizada pelo segundo módulo; Gerenciadores de Diálogo, responsáveis por conduzir o diálogo, processando as entradas dos usuários e gerando saídas. Essa solução permitiu que metade dos usuários que testaram o assistente conseguissem atingir seus objetivos e que a coleta das informações básicas do compromisso fosse feita com uma média de 3 turnos. Permitiu também uma taxa de 84% de acerto na identificação de entidades relevantes e de 53% de acerto na identificação das intenções relevantes expressas pelo usuário.
Tracing Karma in Meiji Japan
Authors: Kameyama Mitsuhiro 
Published: June 2022

Abstract
Despite its doctrinal importance, the concept of karma or karmic causality has come to occupy a complicated place in contemporary Japanese Buddhism, due to its historical connection with discrimination against outcast groups and disabled people. Furthermore, among post-war Japanese intellectuals, the idea of karma has often invoked criticism in the context of modern values such as free will and human potential. Against this conventional framework, this paper demonstrates how the concept of karma was the focus of intense interest among Meiji Japanese intellectuals and a center concern in the developing global network of modern Buddhists. At the intersection of the multifaceted problems facing the Buddhist world at that time—namely, the Buddhist search for scientific religion, civil morality in the nation-building process, reformulating Buddhism for non-Japanese audiences, and the confrontation with competing forms of Western thought—lies the relatively unexamined story of karma in Meiji Japan (1868–1912).
Identification of ruptured intracranial aneurysms using the aneurysm-specific prediction score in patients with multiple aneurysms with subarachnoid hemorrhages- a Chinese population based external validation study
Authors: Zhang Xue-hua , Zhao Xiao-yan , Liu Lan-lan , Wen Li , Wang Guang-xian 
Published: June 2022

Abstract
Background
For patients with aneurysmal subarachnoid hemorrhages (SAHs) and multiple intracranial aneurysms (MIAs), a simple and fast imaging method that can identify ruptured intracranial aneurysms (RIAs) may have great clinical value. We sought to use the aneurysm-specific prediction score to identify RIAs in patients with MIAs and evaluate the aneurysm-specific prediction score.

Methods
Between May 2018 and May 2021, 134 patients with 290 MIAs were retrospectively analyzed. All patients had an SAH due to IA rupture. CT angiography (CTA) was used to assess the maximum diameter, shape, and location of IAs to calculate the aneurysm-specific prediction score. Then, the aneurysm-specific prediction score was applied to RIAs in patients with MIAs.

Results
The IAs with the highest aneurysm-specific prediction scores had not ruptured in 17 (12.7%) of the 134 patients with 290 MIAs. The sensitivity, specificity, false omission rate, diagnostic error rate, and diagnostic accuracy of the aneurysm-specific prediction score were higher than those of the maximum diameter, shape, and location of IAs.

Conclusions
The present study suggests that the aneurysm-specific prediction score has high diagnostic accuracy in identifying RIAs in patients with MIAs and SAH, but that it needs further evaluation.
Association between time of residence and self-perception of distress, interpersonal relationships, and social role in Venezuelan immigrants in Lima, Peru 2018–19: mixed-methods study
Authors: Delgado-Cáceres Frank Milton , Silva-Parra Kevin Angel , Torres-Slimming Paola A. 
Published: June 2022

Abstract
Background
Immigrants arriving in a new country face changes that affect their social, employment, and migratory status. We carried out a mixed-methods study in the rapidly growing Venezuelan immigrant population in Lima, Peru. The objective was to determine whether there was an association between time in Peru and self-perception of symptom distress (SD), interpersonal relationships (IR), and social role (SR).

Methods
The quantitative central component consisted of a cross-sectional study, surveying 152 participants using the Outcome Questionnaire 45.2 (OQ-45.2). The qualitative component, based on phenomenology, explored experiences and challenges during the migration process. Semi-structured in-depth interviews were conducted in 16 informants.

Results
An association that was observed was the increase in the risk of clinically significant SR score with additional years of age. All informants mentioned having witnessed or experienced xenophobia in Peru. Every informant stated that significant labor differences existed between the countries. The most reported somatic symptoms were symptoms of anxiety and alterations of sleep. Additionally, no informant expressed a desire to remain in Peru long term.

Conclusions
A minority of participants registered a clinically significant total score and in each of the three domains of SD, IR, and SR. No association between months in Lima and the self-perception of distress was found. However, this could be due to the short amount of time spent in Peru and any change in self-perception might only be perceived after years or decades spent in Peru. This study is one of the first to use mixed-methods to explore the mental health of the immigrant Venezuelan population.
Standardised 3D-CT lung volumes for patients with idiopathic pulmonary fibrosis
Authors: Tanaka Yuko , Suzuki Yuzo , Hasegawa Hirotsugu , Yokomura Koshi , Fukada Atsuki , Inoue Yusuke , Hozumi Hironao , Karayama Masato , Furuhashi Kazuki , Enomoto Noriyuki , Fujisawa Tomoyuki , Nakamura Yutaro , Inui Naoki , Suda Takafumi 
Published: June 2022

Abstract
Background
The assessment of lung physiology via pulmonary function tests (PFTs) is essential for patients with idiopathic pulmonary fibrosis (IPF). However, PFTs require active participation, which can be challenging for patients with severe respiratory failure, such as during moments of acute exacerbation (AE) of IPF. Recent advances have enabled the re-construction of 3-dimensional computed-tomography (3D-CT) images. This study established a standardisation method and quantitative analysis of lung volume (LV) based on anthropometry using 3D-CT images.

Methods
This is a retrospective multi-center cohort study. The standardised 3D-CT LV in patients with IPF at diagnosis (n = 140) and during AE (cohort1; n = 61 and cohort2; n = 50) and those of controls (n = 53) were assessed.

Results
The standardised 3D-CT LVs at IPF diagnosis were less than those of control patients, especially in the lower lung lobes. The standardised 3D-CT LVs were correlated with forced vital capacity (FVC) and validated using the modified Gender-Age-Physiology (GAP) index. The standardised 3D-CT LVs at IPF diagnosis were independently associated with prognosis. During AE, PFTs were difficult to perform, 3D-CT analyses revealed reduced lung capacity in both the upper and lower lobes compared to those obtained at diagnosis. Lower standardised 3D-CT LVs during AE were independently associated with worse outcomes in the two independent cohorts. In particular, volume loss in the upper lobe at AE had prognostic values.

Conclusions
A novel image quantification method for assessing pulmonary physiology using standardised 3D-CT-derived LVs was developed. This method successfully predicts mortality in patients with IPF and AE of IPF, and may be a useful alternative when PFTs cannot be performed.
Crumbotti and rose petals in a ghost mountain valley: foraging, landscape, and their transformations in the upper Borbera Valley, NW Italy
Authors: Fontefrancesco Michele F. , Zocchi Dauro M. , Cevasco Roberta , Dossche Rebekka , Abidullah Syed , Pieroni Andrea 
Published: June 2022

Abstract
Background
The abandonment of mountain areas in Europe is a process that started during industrialisation and whose traces are still present nowadays. Initiatives aimed at stopping this decline and preserving the local biological and cultural diversities reflect the crucial issue of fostering sustainable rural development. This article contributes to the ongoing debate in assessing and preserving local ecological knowledge (LEK) in a highly marginalised mountain community in the Piedmontese Apennines to support local development. In so doing, it continues a larger project assessing how local botanical knowledge and landscapes evolve over time, in order to understand in more depth which factors affect how LEK is shaped, eroded, and re-created, and how this could be revitalised.

Methods
We compared information about the current gathering and use of local wild plants in the upper Borbera Valley (Carrega Ligure municipality, NW Italy), elicited via 34 in-depth open and semi-structured interviews, with the findings of a field study conducted in the same location, most likely carried out at the end of the 1970s and published in 1981.

Results
There were remarkable quantitative and qualitative differences between the two ethnobotanies. The gathering and use of some wild medicinal plants growing in meadows, woodlands, and higher mountain environments (Achillea, Centaurea, Dianthus, Ostrya, Picea, Polygonum, Potentilla, and Thymus) seems to have disappeared, whereas the collection of plants growing in more anthropogenic environments, or possibly promoted via contacts with the “reference” city of Genoa (the largest city close to Carrega and historically the economic and cultural centre to which the valley was mostly connected), has been introduced (i.e. ramsons, safflower, bitter oranges, black trumpets) or reinvigorated (rose petals). This trend corresponds to the remarkable changes in the local landscape ecology and agro-silvo-pastoral system that took place from the first half of the twentieth century, dramatically increasing woodland and secondary vegetation, and decreasing coppices, plantations, grasslands and segregating cultivated land.

Conclusion
The findings show a very difficult rearrangement of the LEK, as most of the areas the local actors still know are within their villages, and they no longer have daily experience in the rest of the abandoned woodland landscape (except for mushrooming and gathering chestnuts). This situation can be interpreted in two ways: as the start of the complete abandonment of the valley, or as a starting residual resilience lynchpin, which could possibly inspire new residents if the larger political-economic framework would promote measures for making the survival of the mountain settlements of this municipality possible, and not just a chimera.
Novel bilateral symmetrical congenital transverse upper and lower limb deficiencies in siblings in Ethiopia: two case reports
Authors: Melaku Amen Samuel , Bekele Fiker Tadesse , Dires Yilkal Muchie , Wicks Laurence 
Published: June 2022

Abstract
Background
Transverse congenital limb deficiency is a common limb deficiency where there is normal limb development until a certain point, beyond which no anatomical structure exists. Typically, this presents as an isolated and spontaneous abnormality as a result of arrest during limb bud development. Transverse bilateral deficiency in both upper and lower limbs is not well described.

Case presentation
We report the cases of two female Ethiopian amhara siblings, aged 6 years and 5 months, respectively, from Ethiopia with similar transverse bilateral upper and lower limb deficiencies. The sisters were born from the same parents and have similar phenotypic presentations. Neither of them have other syndromic features or systemic manifestations. The siblings are currently on follow-up and are receiving assistance by specialist orthotists, who are working to improve walking and also providing adaptive equipment to facilitate self-care and feeding.

Conclusion
The relationship of the patients and the similarity of phenotypical presentations suggests a strong genetic link.
Fairness in classroom assessment: development and validation of a questionnaire
Authors: Rezai Afsheen 
Published: June 2022

AbstractAlthough fairness in assessment practices has gained noticeable attention over the recent years, there has been a long-lasting study to design and validate a questionnaire to measure it from a psychometric perspective. Thus, this study aims to develop and validate a questionnaire with adequate psychometric properties to measure fairness in classroom assessment. Using a random sampling method, two samples of male and female university students for the first pilot (n = 128) and the second pilot (n = 360) were selected from Ayatollah Borujerdi University and Lorestan University. Drawing on the past literature, a pool of items (n = 118) were extracted and subjected to a 12-step systematic procedure, including content analysis and sampling; creating an item bank; running the first pilot; creating item pool one; expert judgment to evaluate the sub-scales; running an interview and think-aloud protocol; running Cronbach’s alpha; running the second pilot; running exploratory factor analysis, confirmatory factor analysis, and Cronbach’s alpha; creating item pool two; expert review; and translation and translation quality check. Findings yielded a 110-item questionnaire with 10 sub-scales: learning materials and practices (18 items); test design (24 items); opportunities to demonstrate learning (8 items); test administration (21 items); grading (11 items); offering feedback (6 items); tests results interpretation (5 items); decisions based on tests results (3 items); test results consequences (4 items); and students’ fairness-related beliefs and attitudes (10 items). The hope is that this questionnaire can serve research and educational purposes.
Genome and transcriptome analysis of rock-dissolving Pseudomonas sp. NLX-4 strain
Authors: Wu Yanwen , Kameshwar Ayyappa Kumar Sista , Zhang Bo , Chen Feifei , Qin Wensheng , Meng Miaojing , Zhang Jinchi 
Published: June 2022

AbstractMicrobial weathering processes can significantly promote soil properties and reduce rock-to-soil ratio. Some soil-inhabiting bacteria exhibit efficient rock-dissolution abilities by releasing organic acids and other chemical elements from the silicate rocks. However, our understanding of the molecular mechanisms involved during bacterial rock-dissolution is still limited. In this study, we performed silicate rock-dissolution experiments on a Pseudomonas sp. NLX-4 strain isolated from an over-exploited mining site. The results revealed that Pseudomonas sp. NLX-4 strain efficiently accelerates the dissolution of silicate rocks by secreting amino acids, exopolysaccharides, and organic acids. Through employing genome and transcriptome sequencing (RNA-seq), we identified the major regulatory genes. Specifically, 15 differentially expressed genes (DEGs) encoding for siderophore transport, EPS and amino acids synthesis, organic acids metabolism, and bacterial resistance to adverse environmental conditions were highly up-regulated in silicate rock cultures of NLX-4 strain. Our study reports a potential bacterial based approach for improving the ecological restoration of over-exploited rock mining sites.
Graphical Abstract
Economic feasibility of interventions targeted at decreasing piglet perinatal and pre-weaning mortality across European countries
Authors: Stygar Anna H. , Chantziaras Ilias , Maes Dominiek , Aarestrup Moustsen Vivi , De Meyer Dimitri , Quesnel Hélène , Kyriazakis Ilias , Niemi Jarkko K. 
Published: June 2022

AbstractBackgroundPiglet perinatal and pre-weaning mortality is a welfare problem causing economic losses in pig production. In this study, the effects of housing and management interventions on the economic result of sow enterprises representing six European countries (Belgium, Denmark, Finland, Germany, The Netherlands and Spain) were tested. Interventions concerned: (1) installing mechanical ventilation, (2) re-designing of the gestation unit, (3) drying and warming newborn piglets, (4) providing enrichment for gestating sows, including high-fiber dietary supplementation and point-source objects, and (5) music provision and backscratching of sows in the farrowing unit. A bio-economic model was used to determine the effects of interventions on economic outcomes during the nursery phase and to calculate a maximum cost of 1%-point reduction in perinatal and pre-weaning mortality, irrespective of the intervention type. Biological parameters were set according to previous observational and experimental studies. Interventions 1–4 were expected to decrease perinatal mortality, defined as stillbirths and deaths occurring within the first 48 h of postnatal life. Intervention 5 was expected to decrease pre-weaning mortality. Interventions increased fixed (1–3) and variable costs (3–5). We hypothesized that housing and management interventions would have a positive economic effect.ResultsPiglet mortality can be decreased in various ways. Interventions concerning ventilation and re-designing of the gestation unit (1 and 2) were the most beneficial in countries with low housing costs and high perinatal mortality. Drying and warming newborn piglets (3) resulted in varying economic results, with the highest increase in profits obtained in a country with low labor costs and high litter size. Interventions providing sows with enrichment and human–animal interaction (4 and 5) were effective across varying conditions. Regardless of intervention type, policies aiming at 1%-point reduction in perinatal and pre-weaning mortality could cost from €0.2 to €0.5 (average €0.4) and from €0.4 to €0.5 (average €0.5) per piglet, respectively, depending on productions conditions.ConclusionsTo decrease piglet mortality, farmers should consider low input interventions, such as those targeting appropriate behavior. Our results suggest that providing enrichment or increasing human–animal interaction pays off and brings positive economic result even when piglet mortality is marginally reduced.
Implementation of physical activity on prescription for children with obesity in paediatric health care (IMPA): protocol for a feasibility and evaluation study using quantitative and qualitative methods
Authors: Bernhardsson Susanne , Boman Charlotte , Lundqvist Stefan , Arvidsson Daniel , Börjesson Mats , Larsson Maria E. H. , Lundh Hannah , Melin Karin , Nilsen Per , Lauruschkus Katarina 
Published: June 2022

AbstractBackgroundPhysical inactivity is a main cause of childhood obesity which tracks into adulthood obesity, making it important to address early in life. Physical activity on prescription (PAP) is an evidence-based intervention that has shown good effect on physical activity levels in adults, but has not been evaluated in children with obesity. This project aims to evaluate the prerequisites, determinants, and feasibility of implementing PAP adapted to children with obesity and to explore children’s, parents’, and healthcare providers’ experiences of PAP.MethodsIn the first phase of the project, healthcare providers and managers from 26 paediatric clinics in Region Västra Götaland, Sweden, will be invited to participate in a web-based survey and a subset of this sample for a focus group study. Findings from these two data collections will form the basis for adaptation of PAP to the target group and context. In a second phase, this adapted PAP intervention will be evaluated in a clinical study in a sample of approximately 60 children with obesity (ISO-BMI > 30) between 6 and 12 years of age and one of their parents/legal guardians. Implementation process and clinical outcomes will be assessed pre- and post-intervention and at 8 and 12 months’ follow-up. Implementation outcomes are the four core constructs of the Normalization Process Theory; coherence, cognitive participation, collective action, and reflexive monitoring; and appropriateness, acceptability, and feasibility of the PAP intervention. Additional implementation process outcomes are recruitment and attrition rates, intervention fidelity, dose, and adherence. Clinical outcomes are physical activity pattern, BMI, metabolic risk factors, health-related quality of life, sleep, and self-efficacy and motivation for physical activity. Lastly, we will explore the perspectives of children and parents in semi-structured interviews. Design and analysis of the included studies are guided by the Normalization Process Theory.DiscussionThis project will provide new knowledge regarding the feasibility of PAP for children with obesity and about whether and how an evidence-based intervention can be fitted and adapted to new contexts and populations. The results may inform a larger scale trial and future implementation and may enhance the role of PAP in the management of obesity in paediatric health care in Sweden.Trial registrationClinicalTrials.gov Identifier:NCT04847271, registered 14 April 2021.
Manipulation of the Bitcoin market: an agent-based study
Authors: Fratrič Peter , Sileno Giovanni , Klous Sander , van Engers Tom 
Published: June 2022

AbstractFraudulent actions of a trader or a group of traders can cause substantial disturbance to the market, both directly influencing the price of an asset or indirectly by misinforming other market participants. Such behavior can be a source of systemic risk and increasing distrust for the market participants, consequences that call for viable countermeasures. Building on the foundations provided by the extant literature, this study aims to design an agent-based market model capable of reproducing the behavior of the Bitcoin market during the time of an alleged Bitcoin price manipulation that occurred between 2017 and early 2018. The model includes the mechanisms of a limit order book market and several agents associated with different trading strategies, including a fraudulent agent, initialized from empirical data and who performs market manipulation. The model is validated with respect to the Bitcoin price as well as the amount of Bitcoins obtained by the fraudulent agent and the traded volume. Simulation results provide a satisfactory fit to historical data. Several price dips and volume anomalies are explained by the actions of the fraudulent trader, completing the known body of evidence extracted from blockchain activity. The model suggests that the presence of the fraudulent agent was essential to obtain Bitcoin price development in the given time period; without this agent, it would have been very unlikely that the price had reached the heights as it did in late 2017. The insights gained from the model, especially the connection between liquidity and manipulation efficiency, unfold a discussion on how to prevent illicit behavior.