bluuebunny/crossref_metadata_2025_split huggingface dataset:
Elderly aortic stenosis patients' perspectives on treatment goals in transcatheter aortic valvular replacement
Authors: Sugiura Kohei , Kohno Takashi , Hayashida Kentaro , Fujisawa Daisuke , Kitakata Hiroki , Nakano Naomi , Saito Tetsuya , Hase Hiromu , Yoshijima Nobuhiro , Tsuruta Hikaru , Itabashi Yuji , Kohsaka Shun , Fukuda Keiichi 
Published: June 2022

AbstractAimsTranscatheter aortic valvular replacement (TAVR) is increasingly being performed for elderly patients with aortic stenosis (AS), and current guidelines acknowledge the importance of shared decision‐making in their management. This study aimed to evaluate elderly symptomatic severe AS patients' perspectives on their treatment goals and identify factors that influence their treatment choice.Methods and ResultsWe performed a pre‐procedural cross‐sectional survey using a questionnaire at a single university hospital. The questionnaire included three primary domains: (i) symptom burden, (ii) goals and important factors related to treatment, and (iii) preferred place of residence after treatment. We investigated 98 symptomatic severe AS patients who underwent TAVR (median age 86 years, 26% men). None of the patients died during hospitalization, and most of them (94%) were discharged home. Prior to TAVR, the three most common symptom burdens were poor mobility (52%), shortness of breath (52%), and weakness (44%). The reported preferred treatment goals were symptom burden reduction (78%), independence maintenance (68%), ability to perform a specific activity/hobby (62%), and improvement in prognosis (58%). In total, 54% of the patients rated ‘in alignment with my values’ as the factor that affected their decision to undergo TAVR. Nearly all patients (95%) stated that they preferred to live at home after TAVR.ConclusionsAmong elderly AS patients with varying symptoms who underwent TAVR, symptom burden reduction was the most cited patient‐reported goal. Nearly all the patients preferred to live at home after the procedure. Encouraging patients to define their specific goals may improve the quality of shared decision‐making in such settings.
Multi‐channel attack detection based on lightweight message authentication code access control using Internet of Things design
Authors: Kumar Ravula Arun , Vinuthna Kambalapally 
Published: June 2022

AbstractThe Internet of Things (IoT) is a network of interconnected, Internet‐connected items that can gather and transmit data without the need for human interaction through a wireless network. Cryptography is a way of using codes to safeguard information and communications so that only those who are supposed to read and process it may do so. Existing system shows privacy and replication issues caused during cipher text attribute set based encryption. The technical issues in achieving secured authentication is removed by using multi‐channel attack detection based on lightweight message authentication code (LMAC) access control using IoT design in which collision attack can be removed by using secure hash algorithm based Merkle tree and to control sinkhole attacks agent navigation algorithm is proposed and long short‐term memory (LSTM) recurrent neural network (RNN) is proposed to provide the conformity of the user login password. Moreover, to identify attackers on the transmitter side by ensuring authentication, multichannel detection method is proposed. Finally, the security and privacy is improved by using LMAC and user revocation. Thus the multi‐channel attack detection based on LMAC using IoT design can be outperforming the other existing model with higher throughput and low execution time.
Central bank information and private‐sector expectations
Authors: Güntner Jochen 
Published: June 2022

AbstractRecent advances in the literature allow disentangling the pure information component from the interest rate component of US monetary policy surprises. This article quantifies the information revealed around FOMC announcements using forecast revisions from Blue Chip Economic Indicators. Following a typical central bank information shock, survey participants revise their now‐ and short‐term forecasts of both real GDP growth and the GDP deflator upwards, consistent with a shift of the aggregate demand curve along the aggregate supply curve. While now‐ and forecast revisions in real GDP growth are driven by negative central bank information shocks, those in the GDP deflator respond broadly symmetrically to good and bad news.
A generalized two‐factor square‐root framework for modeling occurrences of natural catastrophes
Authors: Orlando Giuseppe , Bufalo Michele 
Published: June 2022

AbstractThis work aims to forecast (over 1, 5, and 15 years) the extremes, the expected value, and the volatility of natural disasters occurrences. To achieve this objective, we adopt a generalized two‐factor square‐root model linking together occurrences and volatility through stochastic correlation (Brownian motion). We use a generalized Pareto distribution (GPD) to forecast the maximum number of occurrences as a measure of value at risk (VaR). The results are checked in terms of accuracy, compared versus some baseline models (i.e., the Poisson process and the extreme value model) and backtested.
Mesenchymal chondrosarcoma of the head and neck with HEY1::NCOA2 fusion: A clinicopathologic and molecular study of 13 cases with emphasis on diagnostic pitfalls
Authors: Xu Bin , Rooper Lisa M. , Dermawan Josephine K. , Zhang Yanming , Suurmeijer Albert J. H. , Dickson Brendan C. , Demicco Elizabeth G. , Antonescu Cristina R. 
Published: June 2022

AbstractBackgroundMesenchymal chondrosarcoma (MCS) is a rare translocation‐associated sarcoma, driven by a canonical HEY1::NCOA2 fusion. The tumors typically have a biphasic phenotype of primitive small blue round cells intermixed with hyaline cartilage. The head and neck (HN) region is a common site for MCS, accounting for 12–45% of all cases reported.AimsWe assembled a relatively large cohort of 13 molecularly confirmed HN MCS for a detailed clinicopathologic analysis. The underlying fusion events were determined using fluorescence in situ hybridization and/or targeted RNA sequencing.ResultsThe median age of presentation was 19 years. Five MCSs (39%) had an intraosseous presentation (skull, maxilla, palate, and mandible), while the remaining eight cases occurred in the brain/meninges, orbit, and nasal cavity. Microscopically, HN MCSs were characterized by primitive round cells arranged in a distinctive nested architecture and a rich staghorn vasculature. A cartilaginous component of hyaline cartilage islands and/or single chondrocytes were present in 69% cases. A combined immunoprofile of CD99(+)/SATB2(+)/CD34(−)/STAT6(−) was typically noted. As this immunoprofile is non‐specific, the referral diagnoses in cases lacking a cartilaginous component included Ewing sarcoma family and osteosarcoma. Among the seven patients with follow‐up data, three developed distant metastasis and one died of disease.ConclusionHN MCS may arise at intra‐ or extra‐osseous sites. The HN MCS appears to have a more prolonged survival compared other MCS sites. Testing for HEY1::NCOA2 fusion is recommended in HN tumors with nested round cell morphology and staghorn vasculature that lack a distinctive cartilaginous component.
Covariate distribution balance via propensity scores
Authors: Sant'Anna Pedro H. C. , Song Xiaojun , Xu Qi 
Published: June 2022

SummaryThis paper proposes new estimators for the propensity score that aim to maximize the covariate distribution balance among different treatment groups. Heuristically, our proposed procedure attempts to estimate a propensity score model by making the underlying covariate distribution of different treatment groups as close to each other as possible. Our estimators are data‐driven and can be used to estimate different treatment effect parameters under different identifying assumptions, including unconfoundedness and local treatment effects. We derive the asymptotic properties of inverse probability weighted estimators for the average, distributional, and quantile treatment effects based on the proposed propensity score estimator and illustrate their finite sample performance via Monte Carlo simulations and an empirical application.
Quantitative assessment of left atrial functions by speckle tracking echocardiography in hypertensive patients with and without retinopathy
Authors: Celik Mehmet , Izci Servet , Kivrak Ulviye , Kup Ayhan , Kahyaoglu Muzaffer , Yilmaz Yusuf , Uslu Abdulkadir , Yilmaz Ahmet Seyda , Celik Fatma Betul , Avci Anil , Cakmak Ender Ozgun , Candan Ozkan , Kanal Yucel , Gecmen Cetin 
Published: June 2022

AbstractPurposeThe association between hypertensive retinopathy and left atrial (LA) impairment is unknown. Accordingly, it was aimed to investigate the possible relationship between hypertensive retinopathy and LA phasic functions by means of two‐dimensional speckle‐tracking echocardiography (2D‐STE).MethodsA total of 124 hypertensive patients and 27 control subjects were included in the study. LA reservoir strain (LAS‐S), LA conduit strain (LAS‐E), and LA booster strain (LAS‐A) parameters were used to evaluate LA myocardial functions.ResultsHypertensive patients (with and without retinopathy) displayed an obvious reduction in the LA reservoir strain (LAS‐S), and LA conduit strain (LAS‐E). Moreover, further impairment in LA reservoir and conduit strain was found in patients with hypertensive retinopathy than in the isolated hypertensive patients. There were no significant differences in LA booster strain (LAS‐A) among the three groups. Impaired LAS‐S (OR: 0.764, CI: 0.657–0.888, and p < 0.001), LAS‐E (OR: 0.754, CI: 0.634–0.897, and p = 0.001), and hypertension (HT) duration (OR: 2.345, CI: 1.568–3.507, and p < 0.001) were shown to be independent predictors of hypertensive retinopathy.ConclusionImpaired LA reservoir and conduit strain may be used to predict hypertensive patients at higher risk of developing hypertensive retinopathy, and to determine which patients should be followed more closely for hypertensive retinopathy.
An ambiguity of laser‐induced degradation in LiFePO4 and advantages of single‐particle approach to Raman spectroscopy
Authors: Ryabin Alexander A. , Pelegov Dmitry V. 
Published: June 2022

AbstractLaser‐induced degradation is a common issue for the Raman spectroscopy study of lithium battery materials. In this work, the combination of single‐particle Raman measurements with scanning electron microscope imaging helped us reveal the variation of the decomposition pathways and products. For the first time, we observed possible laser‐induced melting of the LiFePO4 particles and an unidentified decomposition product, an alternative to previously reported α‐Fe2O3 and γ‐Li3Fe2(PO4)3. These results and analysis of the time series of Raman measurements raise doubts about laser‐induced heating. We suppose non‐thermal amorphization and melting processes due to electronic system excitation by intraband transitions with the following covalent bond destabilization. The role of defects in laser‐induced decomposition is discussed. We hope that this article could help develop a non‐destructive tool for quality control and the study of the electrochemical or thermal degradation of LiFePO4.
Periphyton as a key diet source of essential fatty acids for macroinvertebrates across a nutrient and dissolved organic carbon gradient in boreal lakes
Authors: Vesterinen Jussi , Strandberg Ursula , Taipale Sami J. , Kainz Martin J. , Kankaala Paula 
Published: June 2022

AbstractWe studied how physiologically important long‐chain polyunsaturated fatty acids (PUFA) in benthic macroinvertebrates (Asellus aquaticus, Chironomidae, and Oligochaeta) were related to those in periphyton and terrestrial organic matter (tree leaves), collected from littoral areas of 17 boreal lakes that differed in their dissolved organic carbon (DOC) and nutrient (phosphorus and nitrogen) concentrations. We also analyzed fatty acid (FA)‐specific stable carbon isotopes (δ13CFA) to investigate the dietary origin (periphyton vs. terrestrial organic matter) of PUFA in the consumers. In contrast to periphyton, terrestrial organic matter was deprived of long‐chain PUFA, such as eicosapentaenoic acid (EPA), but rich in short‐chain PUFA. The FA composition of macroinvertebrates was primarily taxon‐specific despite the large differences in DOC and nutrient concentrations of the lakes. An increase in DOC concentration had a negative impact on the EPA content of Asellus, chironomids, and oligochaetes as well as the total FA content of chironomids and oligochaetes. However, the FA content of macroinvertebrates was not related to lake total phosphorus concentrations, although the total FA and EPA content of periphyton increased with the trophic status of the study lakes. The δ13CPUFA values of macroinvertebrates were positively related with the δ13CPUFA of periphyton and weakly with δ13CPUFA of terrestrial leaf material. The results indicate that EPA in the studied macroinvertebrate taxa was mainly derived from an algal‐based diet and not via biosynthesis from allochthonous precursor FA. Thus, macroinvertebrate production in lakes may be limited by the available algae‐based food sources.
Stretchable Optical Diffuser Constructed by Alternate Procedure of Interfacial Complexation and Thermal Crosslinking
Authors: Lin Feng , Huang Hao , Xue Bing , Yang Shuguang 
Published: June 2022

AbstractStretchable optical diffuser is an indispensable photon management element in wearable display devices. Herein, a novel optical diffuser constructed by interfacial hydrogen bonding complexation of methylcellulose (MC), poly(ethylene oxide) (PEO), and polymer complex nanoparticles (PCNP) on transparent polydimethylsiloxane (PDMS) substrate is proposed. The introduction of PEO can toughen the complex film and endow the coating with stretchability. With proper thermal treatment, the polymer complex can be crosslinked through esterification which shows an improved optical diffusion performance and durability. The optimized film exhibits 92% of transmittance (T), 93% of haze (H), and 73% of elongation. It also presents a desirable optical diffusion effect about 88% of T and 93% of H in the stretching state. Moreover, the resulting complex film shows excellent anti‐fatigue capacity which maintains 90% of T and 90% of H after 10 000 stretching cycles. The reported polymer complex film broadens the application of interfacial complexation and demonstrates potential to apply in the integrated wearable optical devices.
Say what you mean, mean what you say: The importance of language in the treatment of obesity
Authors: Fearon Naomi , Sudlow Alexis , le Roux Carel W. , Pournaras Dimitri J. , Welbourn Richard 
Published: June 2022

AbstractObjectiveObesity is a highly stigmatized disease, and despite the understanding of the processes involved, negative language reinforcing outdated views of obesity persists within the scientific literature. This is the first study, to the authors' knowledge, to determine how widespread stigmatizing language is within publications on obesity and examine its impact on patients.MethodsTwo standard terms within obesity publications were identified, and a literature search was carried out to determine their prevalence. A parallel qualitative analysis was conducted with patients with obesity to determine perceptions of these terms.ResultsOf the 3,020 papers screened, 2.4% included the term fail, and 16.8% contained morbid used in conjunction with obesity. Sixteen patients participated in the qualitative analysis. They felt that negative language, particularly failure, implied a personal responsibility for lack of weight loss. Clinically meaningful terminology fostered a more constructive relationship with health care providers.ConclusionsAlthough most journals object to overtly stigmatizing language, using phrases or words that carry negative connotations is less clearly discouraged. It is important to recognize that language that implies a moral responsibility for weight loss or the development of obesity contradicts the well‐established evidence base that obesity results from complex biological processes.
Liquid PEG4‐PLLA copolymers: Effect of chirality and molecular weight on mechanical properties
Authors: Galperin Leonid , Eylon Bat‐hen , Mizrahi Boaz 
Published: June 2022

AbstractThe mechanical properties of polylactic acid (PLA), largely determined by its molecular weight and tacticity, can be modified by copolymerization and multi‐armed structure, among other things. A series of liquid PEG4‐PLA copolymers bearing various PDLLA or PLLA of increasing molecular weights was synthesized and characterized. The glass transition temperature and viscosity gradually increased with the molecular weight and the optical purity of the copolymer's PLA segment. The release profiles of two model drugs, bupivacaine HCl and bovine serum albumin were comparable, and controlled by the molecular weight and dissolution of the polymeric carrier. These findings can help in the development of new applications in biomedicine in which viscosity plays a significant role.
Improved interfacial bonding strength of silicone rubber/carbon fiber modified by dopamine
Authors: Gu Bo , Pu Guohong , Ding Bonan , Zhang Kai , He Ren , Fan Jinghui , Xing Tao , Wu Juying , Yang Wenbin 
Published: June 2022

AbstractA kind of silicone rubber (SR)/carbon fiber (CF)@polydopamine (PDA) flexible composites were prepared in this work. CF was modified by oxidative self‐polymerization of dopamine (DA), and the effect of DA concentration on properties of SR/CF@PDA composites was researched. The transverse fiber bundle tests have shown that SR/CF@PDA‐1.5 has the best interfacial bonding performance. Compared with SR/CF, tensile strength and elongation at break of SR/CF@PDA‐1.5 were increased by 61.7% and 68.4%, respectively. Results indicate that the interfacial bonding of SR/CF@PDA composites was effectively improved due to the adhesion properties of PDA. Moreover, the rough surface of CF@PDA also enhanced the interface interaction through physical “interlocking.” When being compared to other surface modification process, dopamine‐modified carbon fiber is cost effective, “green” and highly efficient. SR/CF@PDA with an excellent interfacial bonding and flexibility is a kind of wrapping material for protection of special precision instruments.
Crosslinked polyethylene: A review on the crosslinking techniques, manufacturing methods, applications, and recycling
Authors: Ahmad Hibal , Rodrigue Denis 
Published: June 2022

AbstractOne of the most used resins in the plastics industry is polyethylene (PE). Although PE has good impact resistance and ductility, its low maximum use temperature and mechanical strength limit some commercial development, especially for load‐bearing applications. To get better overall performances, crosslinking is performed to improve the chemical, mechanical, and thermal properties of PE. Although PE can be crosslinked by using various chemical and physical methods, this makes the resulting polymers more difficult to recycle since a three‐dimensional (3D) network is created. In this review, we first describe the different crosslinking techniques for PE to manufacture crosslinked PE (XLPE) parts. Then, as more than half of the XLPE‐based products are disposed directly after use, we present several options to reuse and recycle these products to overcome this environmental issue and find a sustainable solution. A focus is made on mechanical recycling and de‐crosslinking techniques for XLPE to generate recycled‐XLPE (r‐XLPE). Finally, a conclusion is presented on the current situation and research gaps that must be filled by future works.
Registration of ‘S16‐3747GT’: A high‐yielding determinate maturity group V soybean cultivar with broad biotic and abiotic stressors tolerance
Authors: Chen Pengyin , Shannon J. Grover , Canella Vieira Caio , Nascimento Emanuel Ferrari do , Ali M. Liakat , Lee Dongho , Scaboo Andrew , Crisel Melissa , Smothers Scotty , Clubb Michael , Selves Stewart , Nguyen Henry , Li Zenglu , Mitchum Melissa Goellner , Bond Jason P. , Meinhardt Clinton G. , Usovsky Mariola , Li Shuxian , Gillen Anne M. , Smith James R. , Mengistu Alemu , Zhang Bo , Mozzoni Leandro Angel , Robbins Robert T. , Moseley David 
Published: June 2022

AbstractGiven the magnitude of production losses caused by biotic and abiotic stressors in soybean [Glycine max (L.) Merr.], breeding programs have devoted great efforts to developing high‐yielding soybean cultivars with enhanced genetic resistance to multiple biotic and abiotic stressors. In this context, the University of Missouri–Fisher Delta Research, Extension, and Education Center developed and released the soybean cultivar ‘S16‐3747GT’ (Reg. no. CV‐552, PI 700001). It is a determinate maturity group 5 early (relative maturity 5.0) Roundup Ready 2 (glyphosate‐tolerant) soybean that combines high‐yielding potential with resistance to soybean cyst nematode, southern root‐knot nematode, stem canker, and Phytophthora root rot and with tolerance to salt stress. S16‐3747GT was evaluated in 155 environments across 13 states from 2017 to 2020 and yielded numerically and/or significantly higher than the commercial checks’ average in 9 of 13 states in the southern United States. The broad adaptability and competitiveness across multiple states combined with resistance to biotic and abiotic stressors make S16‐3747GT a compelling cultivar choice for growers in this region as well as an option for public and private soybean breeding programs to incorporate this genetic background into their breeding pipeline.
Psychological factors associated with clinical fear of cancer recurrence in breast cancer patients in the early survivorship period
Authors: Waroquier Pauline , Delevallez France , Razavi Darius , Merckaert Isabelle 
Published: June 2022

AbstractObjectivesClinical fear of cancer recurrence (FCR) is highly prevalent among breast cancer patients and appears early in the disease trajectory. A better understanding of psychological factors associated with clinical FCR is essential to guide screening and intervention development. This cross‐sectional study aimed to assess the contribution of attentional bias, intrusive thoughts, metacognitive beliefs, intolerance of uncertainty, thought suppression, and worry to clinical FCR in breast cancer patients in the early survivorship period.MethodsSeventy‐four patients treated for non‐metastatic breast cancer were enrolled at the end of their treatment. The FCR Inventory‐Short Form (FCRI‐SF) was used to discriminate between the patients with clinical versus nonclinical FCR. Attentional bias to negative and positive cancer‐related and non‐cancer‐related emotional words was assessed with a dot‐probe task. Words were presented for 17, 500, and 1500 ms. Intrusive thoughts and thought suppression were assessed with the White Bear Suppression Inventory, metacognitive beliefs with the Metacognitions Questionnaire‐30, intolerance of uncertainty with the Intolerance of Uncertainty Inventory‐Part A, and worry with the Penn State Worry Questionnaire.ResultsAccording to univariate analyses, the patients with clinical FCR (FCRI‐SF ≥13) significantly differed from those with nonclinical FCR in terms of intrusive thoughts (p = 0.002), metacognitive beliefs (p = 0.029), intolerance of uncertainty (p < 0.001), and worry (p < 0.001). Intolerance of uncertainty (odds ratio, OR = 1.06; p = 0.040) and worry (OR = 1.09; p = 0.013) remained in the final logistic regression models. All the patients showed vigilance to cancer‐related words, whether with negative or positive valence, at automatic stages of processing (17 ms).ConclusionsIntolerance of uncertainty and worry were the two psychological factors contributing directly to clinical FCR in our cross‐sectional study. In addition, attentional bias did not differentiate breast cancer patients with clinical versus nonclinical FCR. Treatment approaches for clinical FCR in early survivorship care may need to integrate uncertainty and worry management intervention strategies.