bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tratamento e controle do Diabetes Mellitus tipo 2 em Unidades de Saúde da Família de um município paulista
Authors: Gomes Gabriel Jeronimo , Sartori Graziela Lopes , Sampaio Aline Moura , Pereira Laura Martins Valdevite , Ueta Julieta Mieko , Oliveira Rinaldo Eduardo Machado de 
Published: September 2022

O diabetes mellitus tipo 2 é uma das doenças crônicas não transmissíveis mais prevalentes e o seu controle adequado na Atenção Primária à Saúde evita complicações e o uso desnecessário de outros serviços de saúde. Neste sentido, o objetivo deste estudo foi analisar o tratamento e controle do diabetes mellitus tipo 2 em Unidades de Saúde da Família de Ribeirão Preto, São Paulo. Trata-se de um estudo longitudinal realizado nos anos de 2016, 2017 e 2018. A amostra foi constituída por cem participantes e coletados dados sociodemográficos, clínicos e laboratoriais. A maioria dos participantes era do sexo feminino (63%) e a média de idade foi de 66,9 anos. Dentre os medicamentos prescritos para o tratamento do diabetes, destacou-se o uso de metformina em monoterapia, seguido de metformina associada às sulfonilureias e insulina associada à antidiabético oral. Verificou-se associação positiva entre o controle glicêmico e idade igual ou superior a sessenta anos, bem como o uso de metformina isoladamente ou em combinação com outros antidiabéticos. Evidenciou-se que, ao longo dos anos, houve aumento na prescrição de medicamentos para o tratamento da doença. Assim, sugere-se o gerenciamento da farmacoterapia pela equipe multiprofissional para a integralidade do cuidado às pessoas com diabetes.
Perfil de Atitudes acerca da Morte e Nível de Resiliência em Técnicos de Enfermagem em Terapia Intensiva
Authors: Ferraboli Silvia de Fátima , Quadros Alexander de , Fernandes Morgana Thaís Carollo 
Published: September 2022

Objetivo: identificar os níveis de Resiliência e o Perfil de Atitudes Acerca da Morte (EAPAM) apresentados por técnicos de enfermagem de uma unidade de terapia intensiva (UTI). Método: Trata-se de uma pesquisa tipo exploratório e transversal, com abordagem quantitativa, desenvolvida a partir da aplicação da Escala ER (Escala de Resiliência) e escala EAPAM (Escala de Avaliação do Perfil de Atitudes Acerca da Morte), ambas autoaplicáveis com respostas do tipo “likert” para técnicos de enfermagem de um hospital federal do Rio Grande do Sul. As variáveis foram descritas por média e desvio padrão. Na análise estatística, para comparação de médias utilizou-se o teste t-student, complementada por Tukey e teste qui-quadrado para comparação de proporções. Para avaliar a associação entre as variáveis contínuas e ordinais, os coeficientes de correlação de Pearson e Spearman foram utilizados, respectivamente. Resultados: Identificou-se que 74% dos técnicos de enfermagem mostram-se resilientes e a Atitude Acerca da Morte mais frequente foi a Aceitação Neutral (87%). Evidenciou-se relação significativa entre a presença de resiliência e atitude de Aceitação Neutral (r=a,298; p=0,004). Conclusão: os dados obtidos permitem vislumbrar fragilidades e potencialidades a serem trabalhadas com a equipe visando seu bem-estar. Como limitação, apontamos à necessidade de estender a avaliação aos demais membros da equipe multiprofissional.
El diálogo que somos: la comprensión como espacio para la política
Authors: Acosta Maria del Rosario 
Published: September 2022

El presente artículo tiene como tarea principal señalar algunos aspectos que hacen pertinente a la hermenéutica dentro del marco de la discusión política, defendiéndola de los ataques que se le han propugnado sobre todo desde una ﬁ losofía de la conciencia crítica como la de Habermas, Adorno y algunos de sus seguidores. Se mostrará, a partir de Gadamer, cómo la hermenéutica responde a dichas críticas en el marco de su propuesta de la comprensión como tarea fundamental y como espacio político primordial. Frente a una ﬁ losofía que apela a la necesidad de una “toma de distancia” como punto de partida de la crítica, único lugar de una verdadera ﬁ losofía y acción políticas, la hermenéutica de Gadamer presenta una alternativa que vale la pena ser rescatada: es en el diá-logo, en el espacio compartido de la comprensión, más que en la crítica, donde el hombre des-encubre las posibilidades de lo que es, donde se da la apertura de su libertad, y, por consiguiente, donde se desenvuelve, en la acción, antes que en la reﬂ exión, el espacio de lo político.
La democracia por venir en la filosofía derrideana: entre la soberanía y la incondicionalidad
Authors: Balcarce Gabriela 
Published: September 2022

El presente artículo intenta realizar una lectura de la noción derrideana de “democracia por venir”. A partir de esta noción el autor realiza una profunda lectura de la problemática de la democracia, tanto en lo que concierne a su fundamentación como a su concepto. Nuestra hipótesis es que la “democracia por venir” permite a Derrida poner en un abismo a la democracia como resistencia a toda clausura totalizante en nombre de lo común y de lo igual. A la vez, nos interesará pensar esta noción en su vinculación con la soberanía y la incondicionalidad, entendida esta última como apertura infinita a la alteridad.Palabras clave:
Colombia y Venezuela: dos países, un pueblo Un análisis comparado de la evolución del Índice de Desarrollo Humano
Authors: Muñoz Téllez John Maximino , Bernal Gómez Daniel Rigoberto 
Published: September 2022

El presente artículo es una revisión y análisis comparado del índice de desarrollo humano entre los estados de Colombia y Venezuela, el cual invita a hacer una reflexión de carácter cuantitativo acerca de la manera en que estas dos naciones se han ubicado en este importante índice de medición, y a partir del análisis que da este programa de las naciones unidas para el desarrollo se aborde de manera histórica el concepto de desarrollo, para que con base en ello se identifique comparativamente y estadísticamente las fases de evolución comparada de estas dos naciones en el contexto de Desarrollo.
ANALISIS POTENSI KEBERLANJUTAN INDUSTRI PENYAMAK KULIT DENGAN STRUKTUR MODAL PINJAMAN SISTEM BUNGA
Authors: Kurniawan Aceng , Sukardi Sukardi , Indrasti Nastiti Siswi , Suparno Ono 
Published: September 2022

Permasalahan kesulitan keuangan yang bisa menyebabkan kebangkrutan terjadi pada industri penyamak kulit di Sukaregang-Garut. Kondisi ini terlihat dari menurunnya jumlah industri penyamak kulit. Disisi lain jumlah industri penyamak kulit yang menggunakan fasilitas pinjamann dengan sistem bunga jumlahnya semakin meningkat. Penelitian ini bertujuan untuk menganalisis potensi keberlanjutan industri penyamak kulit dengan struktur modal pinjaman sistem bunga. Penelitian ini menggunakan metode wawancara dan data yang diperoleh dianalisis dengan menggunakan analisis kebangkrutan Altman Z-Score . Rasio Modal Kerja Terhadap Total Asset (X1), Rasio Laba di Tahan Terhadap Total Asset(X2), Rasio Laba Terhadap Total Asset (X3) dan Rasio Equitas Terhadap Hutang (X4) semakin menurun dengan semakin meningkatnya struktur modal pinjaman sistem bunga. Jumlah pinjaman dengan sistem bunga tidak mempengaruhi nilai Rasio pendapatan terhadap total asset (X5). Rasio Pinjaman di atas 50 peresen pada industri penyamak kulit akan menurunkan potensi keberlanjutan usaha atau menaikan potensi kebangkrutan
ANALISIS PENENTUAN PUSAT-PUSAT PERTUMBUHAN EKONOMI WILAYAH (STUDI PADA SURABAYA, SIDOARJO, GRESIK, MOJOKERTO DAN JOMBANG)
Authors: Lahuddin Lahuddin 
Published: September 2022

Penelitian ini bertujuan untuk mengetahui pusat-pusat pertumbuhan ekonomi wilayah studi pada Surabaya, Sidoarjo, Gresik, Mojokerto dan Jombang. Model analisis yang digunakan pada penelitian ini yaitu model gravitasi dan indeks konektivitas. Hasil penelitian berdasarkan perhitungan Indeks konektivitas Kota Surabaya merupakan daerah yang memiliki indeks konektivitas tertinggi dengan nilai 1,870 sedangkan untuk daerah yang memiliki indeks konektivitas terendah yaitu Kabupaten Mojokerto dengan nilai 1,611. Sehingga Kota Surabaya dapat dijadikan daerah sebagai penghubung wilayah-wilayah lainnya dalam rangka mempercepat pembangunan ekonomi. Sedangkan analisis menggunakan model gravitasi interaksi paling kuat adalah Kabupaten Sidoarjo ke Kota Surabaya dengan nilai 12.531.694.335. Sedangkan untuk interaksi paling rendah yaitu Kabupaten Gresik ke Jombang dengan nilai 178.825.494. pembangunan yang dapat dilakukan oleh Kota Surabaya sebagai pusat pertumbuhan seperti 1) Pengadaan transportasi darat, laut dan udara 2) Peningkatan layanan publik 3) Pembangunan kawasan perdagangan dan jasa.
PRINSIP ITIKAD BAIK DALAM LEMBAGA RECHTSVERWERKING PADA SISTEM AGRARIA INDONESIA
Authors: Ikhwan Mufarrijul , Silmi Munaddhimatus , Dhayaning Bumi Putri Kinanthi 
Published: September 2022

Rechtsverwerking, term of customary law adopted in agrarian law, means losing land rights have been cultivated by other people on basis of good faith. This event can cause legal uncertainty and losses for other parties. This study aims to analyze the principle of good faith in rechtsverwerking in agrarian law, using a statutory and conceptual approach. Based on the analysis, it was found the principle of good faith in rechtsverwerking can be applied to land tenure for a minimum of twenty years and no one has filed a lawsuit for five years after registration at the Land Office. This regulation has consequences for people who previously used the land but were abandoned, then done by other people and the previous land ruler did not carry out certain legal actions, their land rights could potentially be lost. Legal certainty is the purpose of regulation, but it cannot be denied that justice and expediency are also legal goals. So, someone who obtains rights based on rechtsverwerking needs to heed the principle of good faith and the acquisition of his rights does not harm the previous cultivator.
Android Malware Detection Based on Sensitive Patterns
Authors: Liu Kang , Zhang Guanghui , Chen Xue , Liu Qing , Peng Linyu , Liu Yurui 
Published: September 2022

Abstract
In recent years, the rapid increase in the number and type of Android malware has brought great challenges and pressure to malware detection systems. As a widely used method in android malware detection, static detecting has been a hot topic in academia and industry. However, in order to improve the accuracy of detection, the existing static detecting methods sacrifice the excessively high analysis complexity and time cost. Moreover, the correlation between static features leads to redundancy of a large amount of data. Therefore, this paper proposes a static detecting method of Android malware based on sensitive pattern. It uses an improved FP-growth algorithm to mine frequent combinations of sensitive permissions and API calls in malicious apps and benign apps, which avoids the generation of redundant information. In addition, this paper adopts multi-layered gradient boosting decision trees algorithm to train the detection model. And a dual similarity combination method is proposed to measure the similarity between different sensitive patterns. The experimental results show that our proposed detection method has high accuracy and great generalization ability.
Protecting those who protect nature by supporting conservationists’ mental health
Authors: Pienkowski Thomas , Keane Aidan , Tickell Sofia Castelló y , de Lange Emiel , Hazenbosch Mirjam , Khanyari Munib , Arlidge William , Baranyi Gergő , Brittain Stephanie , Kapoor Vena , Mohan Vik , Papworth Sarah , Ravi Roshni , Smit Izak , Milner-Gulland EJ 
Published: September 2022

Abstract
Biodiversity conservation work can be challenging but rewarding, with potential consequences for conservationists’ mental health. Yet, little is known about patterns of mental health among conservationists and its associated protective and risk factors. A better understanding may help improve working conditions, supporting conservationists’ job satisfaction, productivity, and engagement, while reducing costs from staff turnover, absenteeism, and presenteeism. We surveyed 2311 conservation professionals working across 122 countries, asking about experiences of psychological distress, personal characteristics, and workplace conditions. Over half were from and worked in Europe and North America, and most had university-level education, were in desk-based academic and practitioner roles, and responded in English. Moderate or severe distress was reported by 27.8% (Kessler Psychological Distress Scale scores over 24). Respondents with low dispositional and conservation-specific optimism, poor physical health, limited social support, women, and early-career professionals were most at risk in our sample. Heavy workload, job demands, and organisational instability were linked to higher distress, but job stability and satisfaction with one’s contributions to conservation were associated with lower distress. We suggest ways employers and others might ‘promote the positives’ and manage the risks of working in the sector, potentially supporting conservationists’ mental health and abilities to protect nature.
Risk factors of primary postpartum hemorrhage among postnatal mothers in the public hospital of southern Tigray, Ethiopia, 2019: acase-control study
Authors: Muluye Getachew , Woretaw Lebasie , Girma Biniam , Tumebo Tarekegn 
Published: September 2022

Abstract
Background: Postpartum hemorrhage is the most common direct cause of maternal mortality and morbidity; among them, primary postpartum hemorrhages are an enormous element. Although it has an incredible impact on maternal lifestyle, this is the most neglected area in Ethiopia and there is a lack of studies achieved within the study area. So this study aimed to identify the risk factors of primary postpartum hemorrhage among postnatal mothers in public hospitals in southern Tigray, Ethiopia, 2019.
Methods: Institution-based unmatched case-control study design was conducted on 318 (106 case & 212 controls) postnatal mothers in public hospitals of Southern Tigray from January to October 2019. We used a pretested, structured interviewer-administered questionnaire and a chart review to collect the data. Bivariate and multivariable logistic regression models were used to identify the risk factors. P-value < 0.05 was considered statically significant for both steps and an odds ratio with a 95% confidence level was used to see the strength of association. We conducted Hosmer Lemeshow tests to check model goodness of fit.
Results: Abnormal third stage of labor [adjusted odds ratio 5.86, 95%, confidence interval (2.55-13.43), P = 000], cesarean section [adjusted odds ratio 5.61, 95%, confidence interval (2.79-11.30), P = 0.000], lack of active management of third-stage labor [adjusted odds ratio 3.88; 95%, confidence interval (1.29 - 11.60), P = 0.015], absence of labor monitoring by partograph [adjusted odds ratio 3.82, 95%, confidence interval (1.31-11.09), P = 0.014], lack of antenatal care [adjusted odds ratio 2.76, 95%, confidence interval (1.13–6.75), P = 0.026]and complications during pregnancy [adjusted odds ratio 2.79, 95%, confidence interval (1.34-5.83), P = 0.006] were found to be risk factors for primary postpartum hemorrhage.
Conclusions:In this study complications and lack of maternal health interventions in the course of the antepartum and the intrapartum period were found to be risk factors for primary postpartum hemorrhage. A strategy for improving essential maternal health services and detecting and handling complications in a timely manner will help to prevent primary postpartum hemorrhage.
Physics with Continuum Energy Fields of Particles:Unified Equations of Motion from Planetary Motion to Quantum Mechanics
Authors: Misra Prasanta K. , Mansinha Lalu 
Published: September 2022

Abstract
The premise is that two energy fields influence all motion in classical physics. The first is the omnipresent Cosmic Background, the existence of which has been suspected for over a century, but with significant disagreement on the intensity. The second is the Mass Energy Field (ME) hypothesis on the existence of a localised energy field around every particle with mass and/or momentum. The spatial integral of the ME field for every massed particle is given by Einstein’s Mass Energy Equivalence Principle. The ME model leads to startling simplifications of several problems of significance of the past century that were considered almost intractable and required genius innovations: Einstein’s General Relativity (in the Solar System), 1916; Dirac Wave Function, 1928; and the Lamb Shift, 1947. The ME solutions, based on classical physics and conforming to Special Relativity, are simple, compact and do not require spacetime curvature, vacuum fluctuations, or renormalisation. For micro particles the ME model indicates a possible analytic expression for the Casimir Force, Lamb Shift, and the Strong Nuclear Force. The ME field around a massed particle, and the similar momentum energy field around a photon provide a plausible explanation for the century old vexing conundrum of wave-particle duality and points to a possible communication mechanism between quantum entangled particles. The Muon g-factor, computed with the ME expression, very different from existing QED theory, agrees with the measured value to 12 parts per billion. The ME theory shows exact agreement with General Relativity effects within the Solar System.
Regulatory mechanisms of miRNA-126 expression in ulcerative colitis
Authors: Yu Caiyuan , Zhang Guixia , Ye Shicai , Tian Ting , Liang Qianyi , Cui Lijiao , Cen Junwei , Hu Juxiang , Zheng Rong , Wang Hao , Zhou Yu 
Published: September 2022

Abstract
Background and Objective :Our previous studies found that miR-126 was significantly upregulated in ulcerative colitis and promoted inflammatory responses by activating the NF-κB signalling pathway. This study aimed to explore the transcriptional mechanisms involved in miR-126 upregulation.
Methods: miRNAs and mRNAs expression were measured by qRT-PCR. Proteins amounts were measured by Western Blot. The core promoter sequences of miR-126 and its host gene EGFL7 were determined via the luciferase reporter system. Binding of NF-κB3 to the core promoter region of miR-126 was detected by an electrophoretic mobility shift assay (EMSA).
Results: In the HT-29 cell line, stimulation of TNFa, IL-1β, LPS, MDP, HKM, and ODN2006 led to a discordant expression pattern of miR-126 and EGFL7, while IFN-γ or FLA-ST treatment resulted in a concordant expression pattern of miR-126 and EGFL7. Luciferase activity analysis revealed that miR-126 has its own independent promoter. NF-κB3 could directly bind to the core promoter region of miR-126, and regulated the expression of miR-126 and EGFL7.
Conclusion: We demonstrated the first evidence that miR-126 possesses its own independent promoter and could be regulated by NF-κB3 directly. Our study provides further insights into the regulatory mechanisms for the upregulation of miRNA in inflammatory conditions like UC.
A Study on 1D and 2D Seismic Site Response Analysis in a Complex Sedimentary Basin
Authors: Alielahi Hamid , Rahimi Maryam 
Published: September 2022

Abstract
In this study, the seismic behavior of the Persian Gulf Bridge’s complicated basin was evaluated using the FLAC 2D software based on the finite difference method (FDM). A 1D modeling for the soil profile at each pier position of the bridge and a 2D modeling for all piers located on the sedimentary basin was performed. To verify the results of the numerical models, the 1D responses obtained from the FLAC 2D and 1D DEEPSOIL software were compared using the viscoelastic soil behavior. Finding the responses of the bridge piers represents the vital role of the sedimentary basin effects and its 2D geometry on seismic ground motion responses. The results indicated that the seismic responses of the 2D and 1D analysis, such as the seismic wave amplification, predominant period, and the PGA in the complex basin site, differed. Moreover, the 2D amplification effects of the basin site were more prominent than the results of the 1D model in the periodic range of 0.5 to 1 second in a specified profile. Finally, the response spectra obtained from the basin surface at each pier position were compared with the standard design spectrum of the AASHTO code.
TP53 mutation–associated and copy number–dependent KDM7A-DT expression affects DNA repair and promotes invasive breast cancer progression
Authors: Giannakakis Antonis , Tsifintaris Margaritis , Triantafyllou Charisios , Gouzouasis Vasileios , Ow Ghim Siong , Aau Mei Yee , Papp Csaba , Ivshina Anna V. , Kuznetsov Vladimir A. 
Published: September 2022

Abstract

Background Recent characterization of stress-induced promoter-associated antisense lncRNAs (si-paancRNAs) suggests that they modulate transcription and cellular responses to oxidative, metabolic and genotoxic stress and may participate in critical cancer pathways. KDM7A divergent transcript (KDM7A-DT) is one of such stress-induced lncRNAs, whose expression is found deregulated in breast cancer (BC). The mechanisms leading to aberrantKDM7A-DTtranscription, biogenesis, and downstream functions in BC types and subtypes have not been studied. Methods Cell lines, biochemical methods, and profiling experiments were used forKDM7A-DToverexpression and knockdown. Integration of experimental models, bioinformatics, and massive BRCA patient metadata analyses were performed to investigate the mechanisms and functions ofKDM7A-DT. Results StableKDM7A-DToverexpression in nonmalignant cells upregulates p53, CDKN1A, and γH2AX signaling, resulting in a prolonged cell growth retardation phenotype. Importantly,KDM7A-DTinduction by acute oxidative stress in semi-transformed fibroblasts is p53-dependent. According to BC clinical metadata,KDM7A-DTgene alterations are preferentially associated with TP53 missense mutations and highly aggressive, invasive, basal-like (BL) subtype BC poor outcomes. Overall, KDM7A-DT affects DNA repair via the nonhomologous end-joining pathway, inhibits tumor suppressors involved in epithelial-to-mesenchymal transition, induces oncogenic metabolic changes and G2/M checkpoint arrest, and correlates with histology, aneuploidy, hypoxia and BC-associated proteins. Conclusion KDM7A-DT is a TP53 mutation–associated and copy number–dependent pro-oncogene si-paancRNA that contributes to genome instability and modulates BC initiation, progression, invasiveness and outcomes.