bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Clinical Trial of the Relationship Between Anxiety and Lung Function and Respiratory Symptoms in Patients with Asthma, Copd and Copd-Asthma. Assessment of Life Quality
Authors: Ţîrcă Simona Maria , Ciontea Marius Sorin , Vlad Elena , Mihălţan Florin Dumitru 
Published: April 2022

Abstract
Anxiety is a comorbidity among patients with chronic respiratory diseases such as asthma, COPD and COPD-asthma. Anxiety disorders in this population have a considerable influence on asthma management, because they influence the perception of symptoms, and anxiety related to treatment can influence compliance. Patient noncompliance with treatment for chronic respiratory diseases compromises the success of treatment and the patient’s quality of life, while increasing medical costs. Therefore, the aim of our study was to provide patient-centered care and determine which dimension of anxiety is associated with asthma, COPD and COPD-asthma in the general population after controlling age, background and sex. In order to obtain information on the response to treatment, questionnaires on symptom control (Asthma Control Test (ACT), COPD Assessment Test (CAT)) and asses anxiety using the ASQ questionnaire. The result obtained indicates that no compliant person presented a high score of the dimensions (somatic, behavioral and cognitive dimension.) and predominates of anxiety a low overall score. The symptoms associated with anxiety have a low, medium overall score but also a high score on the first visit. The first and second age categories have a low score in both the behavioral and somatic dimensions. In the age category 3 and 4 are people with low score and medium score behavioral dimension and cognitive dimension. In conclusion we can say that through repetitive control we obtained increased treatment compliance was achieved, leading to improved lung function, symptoms control and therefore reduced anxiety in the case of patients with asthma, COPD and COPD-asthma.
The Role of Physical Deconditioning in Cardiological and Pulmonological Medical Practice
Authors: Bivolaru Sorin 
Published: April 2022

Abstract
The examination of the patient with a recent episode of C19 and residual cardiorespiratory symptoms requires a complete two-line assessment of previously undiagnosed chronic pathology. As conventional investigations were insufficient in clarifying the remaining symptomatology, it was necessary to broaden the range of investigations and to take a different approach to this category of patients.
Depending on the symptoms and the patient’s general condition at the beginning of the examination, the attending physician should not disregard the period of restrictions involving significant limitations regarding exercise imposed during the pandemic. Physical exertion minimization and isolation at home have led to a series of functional disorders throughout the body, particularly cardio-respiratory, musculo-articular and neuro-psychiatric disorders.
The effects of a sedentary lifestyle or the lack of physical exertion are not limited to elderly individuals, nor to a single system or apparatus, but have undesirable consequences for the whole body. In this context, the pulmonologist was obliged to answer the question “does the patient have a previously undiagnosed chronic respiratory disease before COVID19 or is the patient physically deconditioned?”. This is how the cardio-respiratory exercise test - the stair-climbing exercise test - came into play in assessing this category of patients. As the medical rehabilitation units could not cope with all the patients, it was necessary to create a home-based rehabilitation programme that was cheap, fast, and allowing telephone monitoring and quantifiable results.
The Evolution of Liver Fibrosis in Patients with Viral C Infection Post Oral Antiviral Treatment
Authors: Gavril Oana Irina , Mitu Radu Sebastian Gavril Florin 
Published: April 2022

Abstract
Hepatitis C virus infection has been for several decades the major cause of cirrhosis and its complications worldwide. However, an arsenal of new and highly effective oral direct-acting antiviral drugs has changed the course of HCV treatment. The effects of HCV elimination are broad and include an overall reduction in mortality in patients with advanced fibrosis, a reduction of the risk of HCC in patients with advanced fibrosis and a reduction in extrahepatic manifestations including HCV-related non-Hodgkin’s lymphoma, other lymphoproliferative disorders and cryoglobulinemic vasculitis. Fibrosis regression is associated with a broad clinical benefit and remains an important therapeutic target in HCV patients who have obtained RSV.
Insights into Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
Authors: Scarlat Gabriel , Dona Bassil , Cârstea Mihai , Stoian Marilena 
Published: April 2022

Abstract
Non-alcoholic fatty liver disease (NAFLD) constitutes a common pathological condition of the liver, the prevalence of which is currently increasing in western countries. NAFLD is frequently diagnosed in males and its incidence is higher in individuals with type 2 diabetes mellitus and obesity. Hence, the disease is considered to be the hepatic manifestation of the metabolic syndrome. A multitude of interconnected risk factors have been described over the years – genetic, hormonal and nutritional, which play important roles in the development of NAFLD. Insulin resistance is considered to be the central pathophysiological condition that promotes the disease in diabetic patients, whereas dyslipidemia and cardiovascular comorbidities (arterial hypertension, ischaemic heart disease) are frequently associated conditions. Although there are currently numerous pathophysiological mechanisms involved in NAFLD that are still unknown or poorly understood, there has been some advancements concerning the pathogenesis of the disease and its progression towards its severe form, known as non-alcoholic steatohepatitis (NASH). In the absence of a clear diagnosis and carefully controlled treatment, NAFLD/NASH may evolve towards liver cirrhosis, liver failure or hepatocellular carcinoma. However, the disease may also generate systemic effects, including the development of chronic kidney disease (CKD). The diagnosis of NAFLD/NASH is based both on its clinical manifestations, revealed by a carefully conducted patient history and physical examination of the patient, and on other investigations; histopathological findings upon liver biopsy, liver ultrasonography and the use of transient elastography (or FibroScan) are some of the most important investigations in NAFLD/NASH. The understanding of the most important risk factors and pathogenic mechanisms of the disease is fundamental for the elaboration of the most efficient treatment, to prevent chronic liver disease or the development of hepatocellular carcinoma.
Obesity-Related Hypertension
Authors: Dobrescu Mariana , Păun Diana , Buculei Sorina , Ghimigean Adina , Poiană Cătălina 
Published: April 2022

Abstract
Obesity is a globally expanding disorder and is the result of the interaction of genetic and environmental factors with the participation of social, behavioural, cultural, physiological, metabolic, and genetic influences. Obesity has profoundly negative effects on the health of the population and induces associated comorbidities such as hypertension, hyperlipidaemia, hyperinsulinemia / insulin resistance. There is ample evidence that obesity causes hypertension, cardiovascular disease, type 2 diabetes, cancer and chronic kidney disease, and the association of obesity with hypertension and other cardiovascular risk factors significantly increases the risk of cardiovascular events.
Vaccination and Covid 19 Infections
Authors: Mihălţan Florin , Constantin Ancuţa 
Published: April 2022

Abstract
In a world plagued by the same multifaceted Covid 19, pros-cons discussions about vaccines, their effectiveness, side effects, fears, and their inclusion in therapeutic strategies have taken on innumerable colors. In this article we will look at the impact of vaccines from the booster regimens to the effects of the booster, all this being seen through the light of the latest research conducted this year.
Prolonged Febrile Syndrome in a Patient with Inflammatory Bowel Disease
Authors: Grigore Monica , Iordache Mihaela , Bănică Cristian , Ioniţă-Radu Florentina , Jinga Mariana , Bucurică Săndica 
Published: April 2022

Abstract
Patients with inflammatory bowel disease (with or without immunosuppressive treatment) have a fragile immune status that predisposes to opportunistic infections. Cytomegalovirus (CMV) is an opportunistic pathogen that determines a large variety of clinical syndromes especially in immunocompromised patients. In inflammatory bowel disease (IBD) patients, his role has long been debated and it is thought that it can complicate the course of the disease. The most frequent clinical manifestation in inflammatory bowel disease patients is represented by CMV colitis, however other clinical manifestations can be met and must also be considered.
We present the case of a young male patient with ulcerative colitis that came to our attention for prolonged febrile syndrome and IBD flare, that was finally confirmed to have CMV disease.
Renal Involvement in Sjogren S Syndrome
Authors: Stoian Marilena 
Published: April 2022

Abstract

Background. Primary Sjogren’s syndrome (pSS) is a chronic progressive autoimmune disorder characterized by lymphocytic infiltration of the exocrine glands, which affects the salivary and lacrimal glands, presenting dryness of the mouth and eyes. Renal involvement is easily ignored by the physicians because the clinical symptoms are often insidious. The most common renal disease in pSS is tubulointerstitial nephritis, responsible for renal tubular acidosis in 20%.

Case report. A 36-year-old woman with polyuria and polydipsia for 10 years ago was admitted to the hospital because asymptomatic hypokalemia, kidney stones, and rashes. This woman presented nephrogenic diabetes insipidus and chronic metabolic acidosis for one year, conditions treated with amiloride and sodium bicarbonate. Anti-Sjögren’s antibody A and B were checked and were both found to be positive. At presentation, she had elevated serum osmolality of 301, with a very low urine osmolality of 61, and serum sodium of 143. A metabolic acidosis with hypokalemia and elevated urine pH are consistent with distal renal tubular acidosis (RTA). A kidney biopsy was obtained, which revealed tubular interstitial fibrosis with infiltration of lymphocytes and plasmacytes who extended into intact cortical parenchyma and was consistent with active chronic interstitial nephritis.

Conclusions. Our presenting patient presented renal manifestations of pSS, including diabetes insipidus, renal tubular acidosis type I, tubulointerstitial nephritis, and nephrolithiasis. None of these findings are common presentations of pSS. The presence of all of these symptoms in one individual makes this patient an atypical way to diagnose a primary Sjogren’s syndrome.
The influence of brand experience on brand equity: the mediating role of brand love in a retail fashion brand
Authors: Ferreira Pedro , Faria Sílvia , Gabriel Carla 
Published: April 2022

Abstract
Based on a retail fashion brand, this article investigates how brand experience affects brand equity when it is mediated by brand love. Actual consumers are well-informed, demanding, and prefer brands that can surprise them over time. As such, offering emotional signals, meaning development, and strategic planning are critical to success when it comes to building strong and enduring relationships with customers. Based on 560 responses to a survey conducted in-store, this study tests the influence of brand experience on overall brand equity, through brand love, using a model of structural equations. The findings imply that brand experience dimensions play a different role in eliciting emotional reactions, such as brand love, which helps to reinforce brand equity. Research on the paths to consumer-based brand equity in the retail environment is still scarce. Exploring this pathway using the customer-brand relationship theory and integrating brand experience and brand love has fascinating potential, but it is still unexplored. Finally, another strength of this research is the test of brand experience dimensions (sensory, intellectual, affective, and behavioral), thus offering more operational insights for theory and practice. The results are based on the study of one brand in one specific country, which limits generalizations. Managers should pay special attention to the emotional impulses provided by a brand to its customers. Building on these triggers via experiences strengthens strong emotional reactions like brand love, which contributes to brand equity.
The Orbán regime as the ‘perfect autocracy’: The emergence of the ‘zombie democracy’ in Hungary
Authors: Ágh Attila 
Published: April 2022

Abstract
All ECE countries have covered the same historical trajectory of ‘the third-generation autocracy’, but Hungary has been reaching its ‘perfection’, since the two-thirds, constitutional supermajority in the Hungarian case has allowed for the Orbán regime to complete this ‘reverse wave’ in all fields of society and turning it into a zombie democracy. The conceptual frame of this paper is that the decline of democracy and the turn to autocratisation can be presented in ECE in the three big stages of the Easy Dream, Chaotic Democracy and Neoliberal Autocracy in the three corresponding decades. The paper concentrates on the third stage in its three shorter periods taking 3–4 years as the De­Democratisation, Autocratisation and De­Europeanisation. The Hungarian case has been presented in this paper in a comparative ECE view as its worst-case scenario that also sheds light on the parallel developments in the fellow ECE countries.
Serious about Integration or Political Posturing? Political Elites and their Impact on Half-hearted Europeanisation in Bosnia and Herzegovina
Authors: Burianová Romana , Hloušek Vít 
Published: April 2022

Abstract
This paper deals with the sluggish Europeanisation efforts of the current political elites of Bosnia and Herzegovina. A typical explanation for the lack of progress would be the complex structure of consociational democracy of the specific Bosnian confederation. The authors, however, claim that the structural obstacles could have been bypassed given the real will of political elites of all three nations to cooperate. The authors examine the role of the structure of the peculiar political system in comparison with the influence of the agency of Bosnian elites on the integration process. The empirical analysis focuses on the situation after the general elections in 2018. The authors discuss the contrast between the official declarations of consistent support for a European future with the real political performance of the various Bosnian party elites. These elites often misuse the institutional settings of the political system to block reforms. They also prefer the politics of obstruction to cement their leading positions within their constituent nations. More than a quarter century after the Dayton Peace Treaty and adoption of the Constitution, the lack of genuine intrinsic motivation to pursue Europeanisation has remained the main reason for the reluctant rapprochement of Bosnia to the European Union.
Constructing the Discourse on the Eurozone Crisis in the Czech Republic: Presidents Václav Klaus and Miloš Zeman Compared
Authors: Marek Dan , Meislová Monika Brusenbauch 
Published: April 2022

Abstract
The article investigates the discourse of two Czech presidents, Václav Klaus (2003–2013) and Miloš Zeman (2013–incumbent), vis­à­vis the salient issue of the Eurozone crisis. Having adopted the general orientation of the discourse historical approach to discourse analysis, and working with a corpus of data on Klaus’ and Zeman’s public utterances on the Eurozone crisis in the 2010–2018 period, the central research question that the article addresses is: How was the Eurozone crisis discursively constructed in the presidential rhetoric of Václav Klaus and Miloš Zeman? Building on the crisis literature, the article answers the question by exploring the presidential discourse within three persuasive narratives of the crisis causes, resolution and consequences.
Could a Referendum Change the Local Party System? Discussion of the Referendum’s Consequences in the Context of Cleavages
Authors: Šenkýřová Barbora , Balík Stanislav 
Published: April 2022

Abstract
The local policy is sometimes degraded by this opinion: in the small village, there is no policy, self-government is based on the personal character without the political context, it is mainly oriented on the technical side of the government. However, different researches confirm that despite this claim local policy contains political (and ideological) fights. These researches focus on different topics and different attitudes in cleavages or conflict study. However, only a few research types mentioned the importance of local civic activism in connection with the local policy trends. It is interesting because civic activism, values and attitudes are the main points in the cleavage topic. In this research, we will discuss the term cleavage (concept by Deegan­Krause) in the context of four Czech municipalities which have experience with civic activism – the referendum. In our research, we will focus on four municipalities, on which we will present the application of the Deegan­Krause model. Based on the application, we will discuss if civic activism in the form of a referendum could lead to changes in the local party system.
The European Union’s Transformative Power in the Countries of the Eastern Partnership
Authors: Sydoruk Tetiana , Pavliuk Viktor , Tymeichuk Iryna 
Published: April 2022

Abstract
The article examines the Eastern Partnership (EaP) as the initiative of the European Union (EU) through the prism of the constructivist concepts of soft power, normative power and transformative power. The research focuses on the assessment of the EU’s transformative strength in Eastern Europe and the South Caucasus, based on the analysis of declared EU policy goals and instruments and the real results of political reforms in partner countries. The results of the study show that the EaP has little transformative impact and needs further revision. The analysis of empirical indicators in the field of political transformation of the EaP countries shows that since its inception, as well as after the signing of Association Agreements with three countries and the renewal of the European Neighborhood Policy in 2015, no radical changes have been made, and the EU’s influence on the course of reforms has been insignificant. Institutional and geopolitical constraints and challenges that complicate the EU’s ability to influence its eastern neighbours are addressed. The article analyses prospects for strengthening the effectiveness of the EaP in the context of its latest update after 2020.
How to follow and Study Through the Sites and Situations of Expert Knowledge Diffusion in International Politics: Research Challenges and Methodological Responses
Authors: Waisová Šárka 
Published: April 2022

Abstract
The central aim of this article is to consider tools and methods for studying expert knowledge (EK) diffusion in international politics. What we need are methodological devices to enable research of the object in motion and to study small or multiple sites, and even global scales in time, as well as the object of inquiry at different levels of analysis. Based on the marriage of network analysis and mobility research this article discusses the research potential of several methodological tools: bibliometrics, QHA, SNA techniques, topology, topography and biography. I conclude that despite these methods being imperfect, they 1) make possible the bridging of traditional IR dilemmas, such as the level­of­analysis problem, the micro­macro gap, and the agent-structure debate, 2) enable to collect and evaluate a much richer class of evidence and contextualization than methods usually used in IR offer, and 3) make possible to be much more ethnographically sensitive than IR research traditionally is.
An extension of the QWERTY effect: Not just the right hand, expertise and typeability predict valence ratings of words
Authors: Buchanan Erin M. , Valentine K. D. , Wilkowsky Addie 
Published: April 2022

Abstract
Typing is a ubiquitous daily action for many individuals; yet, research on how these actions have changed our perception of language is limited. One such influence, deemed the QWERTY effect, is an increase in valence ratings for words typed more with the right hand on a traditional keyboard (Jasmin & Casasanto, 2012). Although this finding is intuitively appealing given both right-handed dominance and the smaller number of letters typed with the right hand, an extension and replication of the right-side advantage is warranted. The present paper re-examined the QWERTY effect expanding to other embodied cognition variables (Barsalou, 1999). First, we found that the right-side advantage is replicable to new valence stimuli. Further, when examining expertise, right-side advantage interacted with typing speed and typeability (i.e., alternating hand key presses or finger switches), portraying that both skill and procedural actions play a role in judgment of valence on words.
Assessment and Accuracy Improvement of Pyroelectric Sensors (Eco-Counter) Based on Visitors Count in National Park. The Case: Monitoring System of Tourist Traffic in Stołowe Mountains National Park, Poland
Authors: Rogowski Mateusz , Piotrowski Krzysztof 
Published: April 2022

Abstract
The monitoring of tourist traffic helps to manage tourism in national parks. Today park managers and researchers use many different devices and technologies that facilitate data collection. Among these often used devices is the pyroelectric sensor. Despite its high degree of usefulness, this type of sensor can miscalculate. Therefore, there is a need to assess the magnitude of errors and the circumstances in which they occur. The purpose of the study was to evaluate pyroelectric sensor counting errors in relation to different visitor flow levels and time intervals between visitors. The study was based on a field experiment and on-site observations using pyroelectric sensors, part of the Monitoring System of tourist traffic (MSTT) in Stołowe Mountains National Park in Poland. The outcome of the assessment was the errors sizes and types and calibration formula. Pyroelectric sensors more often overcount than undercount. Errors occur in larger than 6-visitor groups and time intervals between visitors shorter than 3 seconds. Finally, the analysis of the causes of errors gave the ground to generate the typology of error circumstances. The calibration formula was generated based on a field experiment and on-site observation. The average error size was reduced from ±13 % to ±6 %. The calibration formula provided in the study is simple and universal and can be applied to other data.
Pengaruh EVA, Firm Size, DPR, Dan PBV Terhadap Harga Saham Perusahaan Manufaktur
Authors: Susanto Salim Linda Angelina, 
Published: April 2022

The purpose of this study is to analyze the effect of EVA, firm size, DPR, and PBV on share prices of manufacturing companies listed on the Indonesia Stock Exchange in 2016-2018. The data used in this study were 141 companies using purposive sampling technique. The software used in processing data is Eviews 10.0. F test result show EVA, firm size, DPR, and PBV together have a significant effect on stock prices. T test results show that EVA has a negative and significant effect on stock prices. Firms size has a negative and not significant effect on stock prices, while the DPR and PBV have a positive and not significant effect on stock prices.