bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anatomical variations in coronary venous drainage: Challenges and solutions in delivering cardiac resynchronization therapy
Authors: Akhtar Zaki , Sohal Manav , Kontogiannis Christos , Harding Idris , Zuberi Zia , Bajpai Abhay , Norman Mark , Pearse Simon , Beeton Ian , Gallagher Mark M. 
Published: May 2022

AbstractAimsTo investigate the abnormalities of the coronary venous system in candidates for cardiac resynchronization therapy (CRT) and describe methods for circumventing the resulting difficulties.MethodsFrom four implanting institutes, data of all CRT implants between October 2008 and October 2020 were screened for abnormal cardiac venous anatomy, defined as an anatomical variation not conforming to the accepted ‘normal’ anatomy. Patient demographics, procedural detail, and subsequent left ventricle (LV) lead pacing indices were collected.ResultsFrom a total of 3548 CRT implants, 15 (0.42%) patients (80% male) of 72.2 ± 10.6 years in age with an LV ejection fraction of 34 ± 10.3% were identified to have had an abnormal cardiac venous anatomy over the study period. There were 13 cases of persistent left side superior vena cava (pLSVC), five of which had coronary sinus ostium atresia (CSOA) including two with an “unroofed” coronary sinus (CS); one patient had a unique anomalous origin of the CS and one patient had an isolated CSOA. In total 14 patients (60% repeat attempt) had successful percutaneous implant under general anesthesia (46.7%) via the cephalic vein (59.1%), using the femoral approach (53.3%) for levophase venography and/or pull‐through, including one case of endocardial LV implant. Pacing follow‐up over 37.64 ± 37.6 months demonstrated LV lead threshold between 0.62 and 2.9 volts (pulsewidth 0.4–1.5 ms) in all cases; five patients died within 2.92 ± 1.6 years of a successful implant.ConclusionCRT devices can be implanted percutaneously even in the presence of substantial abnormalities of coronary venous anatomy. Alternative routes of venous access may be required.
Targeted ablation of residual pulmonary vein potentials in atrial fibrillation ablation through ultra‐high‐density mapping: Insights from the CHARISMA registry
Authors: Solimene Francesco , Stabile Giuseppe , Segreti Luca , Malacrida Maurizio , Schillaci Vincenzo , Rossi Pietro , Bongiorni Maria Grazia , Shopova Gergana , Cauti Filippo Maria , Zucchelli Giulio , Arestia Alberto , Bianchi Stefano , Di Cori Andrea , Maddaluno Francesco , De Simone Antonio , Garcia‐Bolao Ignacio 
Published: May 2022

AbstractIntroductionLow‐voltage activity beyond pulmonary veins (PVs) may contribute to the failure of ablation of atrial fibrillation (AF) in the long term. We aimed to assess the presence of gaps (PVG) and residual potential (residual antral potential [RAP]) within the antral scar by means of an ultra‐high‐density mapping (UHDM) system.MethodsWe studied consecutive patients from the CHARISMA registry who were undergoing AF ablation and had complete characterization of residual PV antral activity. The Lumipoint™ (Boston Scientific) map‐analysis tool was used sequentially on each PV component. The ablation endpoint was PV isolation (PVI) and electrical quiescence in the antral region.ResultsFifty‐eight cases of AF ablation were analyzed. A total of 86 PVGs in 34 (58.6%) patients and 44 RAPs in 34 patients (58.6%) were found. In 16 (27.6%) cases, we found at least one RAP in patients with complete absence of PV conduction. RAPs showed a lower mean voltage than PVG (0.3 ± 0.2 mV vs. 0.7 ± 0.5 mV, p < .0001), whereas the mean number of electrogram peaks was higher (8.4 ± 1.4 vs. 3.2 ± 1.5, p < .0001). The percentage of patients in whom RAPs were detected through Lumipoint™ was higher than through propagation map analysis (58.6% vs. 36.2%, p = .025). Acute procedural success was 100%, with all PVs successfully isolated and RAPs completely abolished in all study patients. During a mean follow‐up of 453 ± 133 days, 6 patients (10.3%) suffered an AF/AT recurrence.ConclusionLocal vulnerabilities in antral lesion sets were easily discernible by means of the UHDM system in both de novo and redo patients when no PV conduction was present.
Reactive granulomatous dermatitis as a clinically relevant and unifying term: a retrospective review of clinical features, associated systemic diseases, histopathology and treatment for a series of 65 patients at Mayo Clinic
Authors: Bangalore Kumar A. , Lehman J.S. , Johnson E.F. , Cantwell H.M. , Sartori Valinotti J.C. , Sokumbi O. , Davis M.D.P. , Wetter D.A. 
Published: May 2022

AbstractBackgroundReactive granulomatous dermatitis (RGD) is an umbrella term used to describe interstitial granulomatous dermatitis (IGD), palisaded neutrophilic and granulomatous dermatitis (PNGD), and interstitial granulomatous drug eruption (IGDR).ObjectiveThe aim of this study was to describe systemic associations of RGD, explore possible associations between histopathologic findings and systemic RGD associations and determine clinical relevance of RGD subtypes.MethodsWe retrospectively studied clinical and histopathologic characteristics of patients with RGD from 1990 through 2020.ResultsOf 65 patients with RGD (41 women, 24 men; median age at diagnosis, 62 years), 37 had IGD, 26 had PNGD, and 2 had IGDR. Fifty patients (76.9%) had an associated systemic condition; rheumatologic conditions were identified for 34 (52.3%) patients. The associated systemic condition occurred before RGD in approximately 75% of patients. Statistical analyses did not show significant associations between specific subtypes of RGD and systemic diseases or treatment response, and specific histopathologic findings were not predictive of an associated systemic disease.ConclusionsAlthough most patients with RGD had an associated systemic condition, subtypes of RGD did not correlate with systemic associations, lending support to the use of the umbrella term RGD.
Trends in blood pressure diagnosis, treatment, and control among VA nursing home residents, 2007–2018
Authors: Odden Michelle C. , Li Yongmei , Graham Laura A. , Steinman Michael A. , Marcum Zachary A. , Liu Christine K. , Jing Bocheng , Fung Kathy Z. , Peralta Carmen A. , Lee Sei J. 
Published: May 2022

AbstractBackgroundInadequate treatment of high blood pressure (BP) can lead to preventable adverse events in nursing home residents, while excessive treatment can lead to associated harms.MethodsData were extracted from the VA electronic health record and Bar Code Medication Administration system on 40,079 long‐term care residents aged ≥65 years from October 2006 through September 2018 (FY2007‐2018). Hypertension prevalence at admission was identified by ICD code(s) in the year prior, and antihypertensive medication use was defined as administration ≥50% of days. BP measures were averaged over 2‐year epochs.ResultsThe age‐standardized prevalence of hypertension diagnosis at admission increased from 75.2% in FY2007‐2008 to 85.1% in FY2017‐2018 (p‐value for trend <0.001). Rates of BP treatment and control among residents with hypertension at admission declined slightly over time (p‐values for trend <0.001) but remained high (80.3% treated in FY2017‐2018, 80.1% with average BP <140/90 mmHg). The age‐adjusted prevalence of chronic low BP (average <90/60 mmHg) also declined from 11.1% in FY2007‐2008 to 4.7% in FY2017‐2018 (p‐value for trend <0.001). Persons identified as Black race or Hispanic ethnicity and those with a history of diabetes, stroke, and renal disease were less likely to have an average BP <140/90 mmHg.ConclusionsHypertension is well controlled in VA nursing homes, and recent trends of less intensive BP control were accompanied by a lower prevalence of chronic low BP. Nonetheless, some high‐risk populations have average BP levels >140/90 mmHg. Future research is needed to better understand the benefits and harms of BP control in nursing home residents.
From carbon neutral to climate neutral: Dynamic life cycle assessment for wood‐based panels produced in China
Authors: Wang Shanshan , Chen Jiaxin , Ter‐Mikaelian Michael T. , Levasseur Annie , Yang Hongqiang 
Published: May 2022

AbstractThe forestry sector is crucial in supporting climate change mitigation, where the mitigation potential is assessed by combining forest carbon analysis and wood product life cycle assessment (LCA). Static LCA (sLCA) is the approach commonly used in national forestry mitigation models worldwide. Static GHG effects are calculated as a running total of emissions and removals, which are often used to imply climate effects. Also, carbon neutrality, a state when the GHG effects equal zero, is used to imply neutral climate effects. However, until carbon neutrality is achieved, the increased emissions contribute to climate warming. Dynamic LCA (dLCA) is an improved method to estimate climate effects by considering the atmospheric dynamics and heat trapping capacity of different GHGs. Climate neutrality is a state when the warming effects caused by increased emissions are fully compensated by warming reduction contributed by removals. We applied dLCA and sLCA to China‐made wood‐based panels produced from 1990 to 2018 by harvesting poplar plantations. Our results suggested that, compared to dLCA results, static GHG effects largely underestimated climate warming effects or overestimated mitigation contributions. Also, decades or longer was required to achieve climate neutrality following carbon neutrality, if achievable. So, within a given timeframe, a forestry mitigation activity can achieve carbon neutrality but increase climate warming, hindering the goal of limiting global temperature rise that was set in the 2015 Paris Agreement. Thus, to assess climate warming effects, using dLCA in addition to GHG effects is essential for forestry mitigation analysis.
Antidepressant use During Pregnancy: Knowledge, Attitudes, and Decision‐Making of Patients and Providers
Authors: Eakley Rachel , Lyndon Audrey 
Published: May 2022

IntroductionDespite the risks associated with untreated perinatal depression and anxiety, both patients and clinicians are less likely to follow evidence‐based guidelines including the use of antidepressants during pregnancy. The aim of this integrative review was to describe the perspectives of both patients and prescribing health care providers regarding the use of antidepressants during pregnancy.MethodsWe performed a literature search in PubMed, CINAHL, ProQuest Central, and PsychINFO. Inclusion criteria were English language, original peer‐reviewed research published within the previous 10 years that described perspectives regarding the use of antidepressants of pregnant patients or prescribing providers during pregnancy. Studies were excluded if their focus was on screening practices, treatment guidelines, or evaluation of decision support tool; medication or treatment broadly; bipolar disorder or serious mental illness; or they did not provide patient or provider perspective. This review was limited to professionals with scopes of practice that include prescriptive authority (eg, physicians, advanced practices nurses, midwives). Included articles were critically appraised and read in an iterative process to extract methodological details and synthesize findings.ResultsNineteen studies met criteria for inclusion and varied by design, sample, and quality. Together, the reviewed articles suggest that patients and prescribing providers hold a range of beliefs regarding the safety of antidepressant during pregnancy. Patients and providers appear to value different sources of information and varied in awareness of the negative impacts of untreated depression and anxiety during pregnancy. Many patients report dissatisfaction with available information and distress throughout the decision‐making experience. Notably, patients and providers had incongruent perceptions of the others’ experience.DiscussionInconsistencies between knowledge, attitudes, and decision‐making highlight the need for improved dissemination of evidence‐based treatments and support increased training for psychopharmacology during pregnancy. Efforts to reduce patient distress regarding their decisions, such as adequate time and information, are indicated.
Best‐Fit Algorithm Influences on Virtual Casts’ Alignment Discrepancies
Authors: Revilla‐León Marta , Gohil Aishwa , Barmak Abdul B. , Zandinejad Amirali , Raigrodski Ariel J. , Alonso Pérez‐Barquero Jorge 
Published: May 2022

AbstractPurposeTo measure the influence of best‐fit (BF) algorithms (entire dataset, 3 or 6 points landmark‐based, or section‐based BF) on virtual casts and their alignment discrepancies.Material and methodsA mandibular typodont was obtained and digitized by using an industrial scanner (GOM Atos Q 3D 12M). A control mesh was acquired. The typodont was digitized by using an intraoral scanner (TRIOS 4). Based on the alignment procedures, four groups were created: BF of the entire dataset (BF group), landmark‐based BF using 3 reference points (LBF‐3 group), or 6 reference points (LBF‐6 group), and section‐based BF (SBF group). The root mean square (RMS) error was calculated. One‐way ANOVA and post hoc pairwise multi‐comparison Tukey were used to analyze the data (α = 0.05).ResultsSignificant RMS error mean value differences were found across the groups (p < 0.001). Tukey test revealed significant RMS error mean value differences between the BF and LBF‐3 groups (p = 0.022), BF and LBF‐6 groups (p < 0.001), LB‐3 and LB‐6 groups (p < 0.001), LBF‐3 and SBF groups (p < 0.001), and LBF‐6 and SBF groups (p < 0.001). The LBF‐6 group had the lowest trueness, while SBF and BF groups obtained the highest trueness values. Furthermore, significant SD differences were revealed across the groups tested (p < 0.001). Tukey test revealed significant SD differences between the BF and LBF‐6 groups (p < 0.001), LBF‐3 and LB‐6 groups (p < 0.001), LBF‐3 and SBF groups (p = 0.004), and LBF‐6 and SBF groups (p < 0.001). The BF and SBF groups showed equal and highest precision, while the LBF‐6 group had the lowest precision.ConclusionsThe best‐fit algorithms tested influenced the virtual casts’ alignment discrepancy. Entire dataset or section‐based best‐fit algorithms obtained the highest virtual casts’ alignment trueness and precision compared with the landmark‐based method.
Dietary supplementation of spirulina and canthaxanthin boosts laying performance, lipid profile in blood and egg yolk, hatchability, and semen quality of chickens
Authors: Ismail Fawzy , Sherif Khalil , Rizk Yasser , Hassan Montaha , Mekawy Aml , Mahrose Khalid 
Published: May 2022

AbstractThis study examined the impacts of dietary spirulina (SP) and canthaxanthin (CX) supplementation to laying hens on reproductive performance and cock's semen quality evaluation. Three hundred and sixty of indigenous Sinai chickens (300 hens + 60 cocks), 48‐weeks‐old, were randomly divided into five treatments; a control and four supplemented (0.6 g SP mg/kg, 0.8 g SP mg/kg, 6 mg CX/kg diet, and 8 mg CX/kg diet) with six replications of 10 females and 1 male per treatment for laying trial and 1 male for semen evaluation. The animals were fed with experimental diets for 12 weeks. Supplementing 6 mg CX/kg diet led to an increase in the final body weight and egg production traits, while 8 mg CX/kg diet resulted in an improving feed conversion ratio. Supplementation of 0.6 g SP mg/kg or 6.0 mg CX/kg diet resulted in the highest egg production. The heaviest egg weight and egg mass were induced by 0.8 g SP mg/kg. Eggs laid from hens fed 0.6 g SP/kg diet had a higher concentration of cholesterol than those fed 0.8 g SP/kg and those fed 6.0 and 8.0 mg CX/kg. Cocks fed 6 mg CX/kg and those fed 0.8 g SP/kg diet had the greatest sperm concentration. The supplementation of 0.8 g SP mg/kg diet or both 6 and 8 mg CX/kg diet enhanced hatchability. So, dietary spirulina (0.8 mg/kg) and canthaxanthin (6 mg/kg) supplementation to Sinai laying hens and cocks could be used to improve productive and reproductive and performance.
Prevalence of chronic pulmonary aspergillosis regarding time of tuberculosis diagnosis in Brazil
Authors: Volpe‐Chaves Cláudia E. , Venturini James , B. Castilho Suse , S. O. Fonseca Simone , F. Nunes Thiago , T. Cunha Eunice A. , M. E. Lima Gláucia , O. Nunes Maína , P. Vicentini Adriana , V. L. Oliveira Sandra M. , Carvalho Lídia R. , Thompson Luis , P. Mendes Rinaldo , M. M. Paniago Anamaria 
Published: May 2022

AbstractBackgroundData on the prevalence of chronic pulmonary aspergillosis (CPA) in patients with active or cured tuberculosis (TB) are scarce, mainly due to diagnostic difficulties. The diagnosis of CPA is based on pulmonary symptoms and chest computed tomography (CT) scans and is considered confirmed when there is microbiological or serological evidence ofAspergillusspp. infection.ObjectivesTo estimate the prevalence of CPA in patients treated or undergoing treatment for PTB, seen in two referral hospitals in Mato Grosso do Sul, Brazil.Patients and MethodsA total of 193 consecutive patients who were treated or previously treated for pulmonary tuberculosis underwent prospective evaluation: (a) clinical evaluation; (b) chest CT scan; (c) sputum examination—culture for fungi and smears for direct mycology; (d) detection of anti‐Aspergillus fumigatusantibodies using an enzyme‐linked immunosorbent assay Platelia® test; and (e) anti‐Aspergillusspp. antibodies were assessed via a DID test.ResultsThe global prevalence of CPA was 10.9% (95% confidence interval, 7.2%–16.1%), but it increased with the time of TB diagnosis. The variables independently associated with CPA were previous pulmonary tuberculosis over 4 years ago and haemoptysis. Cavities, pleural thickening and the presence of a fungal ball were the most frequent tomographic findings in patients with CPA.ConclusionsThe high prevalence observed and its increase over time suggest the need for continuous surveillance of CPA in patients with active or previous pulmonary tuberculosis and throughout life, with clinical, tomographic and serological evaluations (ELISA) for a timely diagnosis and a better prognosis.
Disinfection trials with terbinafine‐susceptible and terbinafine‐resistant dermatophytes
Authors: Skaastrup Kristoffer Nagy , Astvad Karen Marie Thyssen , Arendrup Maiken Cavling , Jemec Gregor Borut Ernst , Saunte Ditte Marie Lindhardt 
Published: May 2022

AbstractBackgroundTreatment of tinea pedis and onychomycosis is complicated by high rates of reinfection and the emergence of terbinafine‐resistant strains of Trichophyton spp. Effective disinfection of contaminated socks is an important measure. Appropriate washing reduces the risk of reinfection and is paramount in treating tinea pedis and onychomycosis.ObjectivesThe aim of this study was to describe the effect of commonplace disinfection methods using socks pieces inoculated with terbinafine‐resistant or terbinafine‐susceptible isolates of Trichophyton spp.MethodsSock pieces were inoculated with seven terbinafine‐resistant isolates of Trichophyton spp. with known mutations in the SQLE‐gene (T. rubrum (n = 3), T. interdigitale (n = 1) and T. indotineae (n = 3)) and six terbinafine‐susceptible isolates of Trichophyton spp. (T. rubrum (n = 3) and T. interdigitale (n = 3)). Methods of disinfection included soaking in a quaternary ammonium (QAC) detergent (0.5, 2 and 24 h), freezing at −20°C (0.5, 12 and 24 h), domestic and steam washing (both at 40°C with detergent). Sock pieces were cultured for 4 weeks following disinfection. The primary end point was no growth at the end of week 4.ResultsSoaking in a QAC‐detergent for 24 h procured at disinfectant rate of 100% (13/13), whilst soaking in 0.5 and 2 h had a disinfectant rate of 46.2% (6/13) and 84.6% (11/13), respectively. Domestic washing (40°C with detergent) produced a disinfectant rate of 7.7% (1/13). Freezing at −20°C (0.5, 12 and 24 h) and steam washing (40°C with detergent) had no disinfectant properties.ConclusionsSoaking in a QAC‐detergent for 24 h effectively disinfected sock pieces contaminated with dermatophytes.
Postoperative nursing care of a child with pulmonary artery displacement combined with slide tracheobronchial plasty
Authors: Jin Chendi , Lin Nan , Yang Shanfeng , Yan Chuanchuan , Li Shuaini , Wu Xiujing , Zhu Jihua 
Published: May 2022

AbstractGenerally, pulmonary artery sling operation involves the pulmonary artery transplantation to be cut off. Nursing care is focused on the postoperative pulmonary vascular anastomosis, respiratory tract, and blood pressure after surgery. We report the case of an infant who underwent pulmonary artery tracheal transposition combined with Slide keratoplasty, where the pulmonary artery transplantation was not cut off. We highlight that postoperative pulmonary artery blood flow to the unobstructed airway and airway reconstruction surgery should be focused on to help children recover and ensure successful surgery. This case study reports the postoperative nursing experience of one patient with pulmonary artery sling undergoing pulmonary tracheal transposition combined with Slide arthroplasty. This demonstrates that throughout the postoperative care, airway management should be focused on to maintain circulation stability in the early postoperative period, and corresponding measures such as posture management, atomization inhalation, and improved chest physical therapy should be applied according to the special surgical method of the case in order to reduce airway complications and to improve the surgical success rate of children with pulmonary artery sling undergoing pulmonary tracheal transposition combined with Slide arthroplasty. In similar cases, after pulmonary tracheal transposition and Slide angioplasty, the doctors and nurses should pay attention to early circulation stability and focus on airway management through careful treatment and nursing, so as to promote the child's recovery.
Effect of a carbohydrate lollipop on the gastric volume of fasted pediatric patients
Authors: Odendaal Pieter , Burke Annemie , Coetzee Johan 
Published: May 2022

AbstractBackgroundPreoperative fasting is part of routine practice. Children subjected to prolonged preoperative fasting often suffer adverse effects. Consuming a preoperative lollipop may lessen their anxiety and have clinical benefits.AimsTo assess the effect of consuming a lollipop on gastric volume and the feasibility of administering a lollipop to a child preoperatively.MethodsIn this prospective, repeated measures interventional study, we measured gastric antrum volume using ultrasound in children aged 2–18 years. We measured antrum volumes after participants had fasted for a minimum of 6 h for solids and 2 h for clear fluids. They then consumed a standard carbohydrate lollipop, and we repeated the antrum volume measurements after 1 h.ResultsOf the 38 patients enrolled, 32 completed the study; four had ingested additional food or liquid, and two were diagnosed with systemic disease the day after data collection. The gastric volume data were normally distributed. The mean volume change was 0.01 ml kg−1 (95% CI −0.02 to 0.05; p = .460). The mean postlollipop volume was 0.51 ml kg−1 (95% CI 0.43 to 0.58).ConclusionsConsuming a standard lollipop did not affect the gastric volume of fasted pediatric patients.