bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alpine Assets, Perceptions and Strategies for Nature-Based Health Tourism
Authors: Mosedale Jan , Hartl Arnulf , Pichler Christina , Bischof Michael 
Published: November 2022

AbstractNature-based health tourism is experiencing a resurgence. To determine its potential as a development opportunity for alpine destinations, it is necessary to analyse both the demand and supply side. Two surveys were conducted: a representative survey of the population of six countries of the Alpine Space exploring the perception of the Alps as a healthy destination in general and on the personal assessment of the health effect of natural resources in particular and an exploratory survey of tourism stakeholders in destination management, accommodation and gastronomy as well as (health) tourism services with a focus on the expected economic developments and the relevance of individual target groups for nature-based health tourism. The results demonstrate the need for a strategic development process which aligns perceptions with destination strategy and pre-existing offers. Two potential strategies are briefly outlined: 1. destinations with non-locally specific alpine natural health resources can develop broad tourism experiences for health conditions that occur across society with health a secondary aspect in marketing. 2. destinations featuring locally specific natural health resources with proven evidence can develop offers for a specific condition and are thus able to target a very specific group.
An Ontology-Based Decision Support System to Foster Innovation and Competitiveness Opportunities of Health Tourism Destinations
Authors: Spoladore Daniele , Pessot Elena 
Published: November 2022

AbstractThe competitiveness of nature-based Health Tourism (NHT) industry, especially in the Alpine regions, is increasingly linked to the sustainability and exploitation of unique natural resources of tourism destinations, which often lack the access to knowledge and networks of stakeholders to improve their offerings. In this sense, the use of digital tools can open up further opportunities to reconsider value offerings and better access different knowledge resources and relationships within the industry network. This Chapter illustrates the collaborative design approach adopted in HEALPS2 for the development of an ontology-based Decision Support System for health tourism destinations. The resulting ontology aims to model the relationships between the available natural resources, the value offerings and the target groups of NHT destinations. Moreover, the Collaborative Design approach foresees the involvement of end-users (i.e. not only tourism destinations, but also the network of stakeholders, and the actual and potential future tourists) as both sources of knowledge and validators of the ontology and its outputs, aiming to inform decision-making processes in a shared knowledge model that leverages on digital tools.
A Methodology for Participatory Stakeholder Engagement in Nature-Based Health Tourism
Authors: Čeh Danilo , Nenad Mirjana , Pessot Elena 
Published: November 2022

AbstractParticipatory stakeholder engagement in strategy-making, for industries such as Nature-based Health Tourism (NHT), enhances the delivery of more useful and applicable strategies, with also higher chances to reach intended goals if compared to conventional top-down planning processes. This chapter describes the methodology identified and carried out in the HEALPS2 project to efficiently reach and engage stakeholders of Alpine NHT and to form a stakeholder group at the transnational level (including the engagement of EU-level ac-tors and networks). Based on the Quadruple Helix concept, the methodology integrates a process of stakeholder engagement and endorsement along three steps; the identification of the key points and the problems to be tackled for a successful stakeholder engagement; and the development of Regional and Transnational Stakeholder Groups that extend to the cooperation with EU-wide networks. Developing health tourism products and service chains, and sustaining them with strategies and policies, is a complex undertaking. The adoption of the stakeholder engagement approaches throughout the HEALPS2 project showed that it is of utmost importance to properly identify, involve and communicate with the stakeholders who effectively complement the success of the project, and its outcomes, in enhancing NHT competitiveness.
Innovation Practices and Techniques for Nature-Based Health Tourism Competitiveness
Authors: Nenad Mirjana , Pessot Elena 
Published: November 2022

AbstractInnovation is considered essential to the growth and long-term sustainability of health tourism companies and destinations. Continuous innovation takes place to improve the industry competitiveness, but especially the tourists’ experience and wellness with new product offerings. This Chapter collects and describes the innovation practices proposed and developed in some pilot regions of the HEALPS2 project consortium. The innovation practices identified in the project can be subdivided into three types, i.e., innovation techniques, innovation supporting tools, and innovative product offerings. All the practices were designed to target several operators of the Nature-based Health Tourism (NHT) industry, from tourism facilities and companies (especially small- and medium-sized enterprises) to regional councils and municipalities in charge of policy-making and tourism strategy development. HEALPS 2 innovation practices and techniques can be purposefully integrated at the regional and local level for a more innovation-driven industry strategy and business development, as well as facilitation of transnational cooperation among key actors, also beyond Alpine regions and NHT destinations.
Simplicity of Augmentations of Codimension 1 Germs and by Morse Functions
Authors: Breva Ribes I. , Oset Sinha R. 
Published: November 2022

AbstractWe study the simplicity of map-germs obtained by the operation of augmentation and describe how to obtain their versal unfoldings. When the augmentation comes from an $${\mathscr {A}}_e$$

A
e

-codimension 1 germ or the augmenting function is a Morse function, we give a complete characterisation for simplicity. These characterisations yield all the simple augmentations in all explicitly obtained classifications of $${\mathscr {A}}$$
A
-simple monogerms except for one ($$F_4$$

F
4

in Mond’s list from $$\mathbb C^2$$

C
2

to $$\mathbb C^3$$

C
3

). Moreover, using our results we produce a list of corank 1 simple augmentations from $$\mathbb C^4$$

C
4

to $$\mathbb C^4$$

C
4

.
A new knee arthrometer demonstrated to be reliable and accurate to assess anterior tibial translation in comparison with stress radiographs
Authors: Milano Giuseppe , Colosio Alessandro , Scaini Alessandra , Motta Marcello , Raggi Andrea , Zanoni Fabio , Galli Stefano , Saccomanno Maristella F. 
Published: November 2022

Abstract
Introduction
For several years, many arthrometers have been developed to assess anterior knee laxity. The aim of our study was to evaluate the validity of a new practical and handy testing device with the hypothesis that the new arthrometer had good validity in terms of reliability and accuracy.

Methods
Lachman test was performed on five fresh frozen cadaveric knees by five examiners. Anterior tibial translation (ATT) was measured with a new arthrometer (BLU-DAT) and on lateral stress radiographs. Data on ATT were obtained under 7 kg (69 N), 9 kg (88 N), and maximum manual traction (MMT). Tests were performed on the same specimens before and after arthroscopic ACL excision. Inter-rater reliability of the BLU-DAT measures was assessed with the intraclass correlation coefficient (ICC) for single and average measurements. The Bland–Altman method was used to estimate agreement between the BLU-DAT and stress radiographs.

Results
ICC values for single measurements were 0.62, 0.54 and 0.58 for 7-kg, 9-kg and MMT assessment, respectively. Overall reliability was good (ICC = 0.63). ICC values for average measurements were 0.89, 0.85 and 0.88 for 7-kg, 9-kg and MMT assessment, respectively. Overall reliability was very good (ICC = 0.90) SEM ranged from 1.4 mm to 1.6 mm for single measurements and was below 1 mm at each testing condition for average measurements. Analysis of agreement between BLU-DAT and radiographic measurements showed a mean difference equal to 0.83 mm ± 2.1 mm (95% CI: 0.55–1.11). Upper LOA was equal to 4.9 mm (95% CI: 5.39–4.41). Lower LOA was equal to − 3.2 mm (95% CI: − 2.71 to − 3.69).

Conclusion
Measurement of anterior knee laxity with the BLU-DAT testing device has a good to very good inter-rater reliability and good agreement with a gold standard such as stress radiographs.
Cadaveric Diagnostic Study, Level of Evidence IV.
Link between melt-impregnation and metamorphism of Atlantis Massif peridotite (IODP Expedition 357)
Authors: Whattam Scott A. , De Hoog Jan C. M. , Leybourne Matthew I. , Khedr Mohamed Zaki 
Published: November 2022

AbstractIODP Expedition 357 drilled 17 shallow sites scattered over ~ 10 km in the west to east spreading direction across the Atlantis Massif oceanic core complex (OCC, MAR, 30 ºN). Mantle exposed in the footwall of the Atlantic Massif OCC is nearly wholly serpentinized (80–100%) harzburgite and subordinate dunite. A recent whole-rock chemistry study by Whattam et al. (Chemical Geology 594. 10.1016/j.chemgeo.2021.120681, 2022) subdivides Atlantis Massif peridotites into: Type I fluid–rock dominated serpentinite, which exhibits almost nil evidence of melt-impregnation or silica metasomatism; Type II melt–rock dominated, mafic melt-impregnated serpentinite; and Type III melt–rock dominated Si-metasomatized serpentinite. In this study, on the basis of EPMA, three kinds of Cr–spinel are distinguished in Expedition 357 serpentinite: (I) primary, unmetamorphosed mantle array, (II) low-Ti metamorphosed, and (III) high-Ti melt reacted. All Cr–spinel of western site Type I serpentinite is unmetamorphosed (n = 34) and comprises 68% of all unmetamorphosed Cr–spinel. Metamorphosed Cr–spinel (n = 100) are the most abundant and occur in the central and eastern site Type II and Type III serpentinite, whereas melt-reacted Cr–spinel and chromite are restricted to the central sites and occur predominantly in serpentinized dunite. Estimates of the degree of melt extraction of Type I serpentinite using F = 10ln(spinel Cr#) + 24 are ~ 9–17%. Fugacity calculations of primary, unmetamorphosed Cr–spinel yield Δlog(fO2)FMQ of − 1.7 to + 1.0 and calculations using olivine–spinel Mg–Fe exchange thermometry yield a mean closure temperature of 808 ± 39 °C. Mafic melt-impregnation resulted in Cr–spinel with anomalously high TiO2 of 0.27–0.68 wt.% and production of Ti-rich chromite (up to 1.23 wt.% TiO2). Greenschist facies metamorphism (< 500 °C) resulted in Mg–Fe2+ exchange between Cr–spinel and forsterite and anomalously low Cr–spinel Mg#; higher degrees of amphibolite facies metamorphism (~ 500–700 °C) also resulted in anomalously high Cr# due to Al–Cr exchange. As has been previously established, significant Al loss from chromite cores above 550 °C is the result of equilibration with fluids in equilibrium with chlorite, which may be valid for our samples. On the basis of Cr–spinel vs. whole-rock compositions, a clear relationship exists between melt-impregnation and metamorphism of central and eastern serpentinite, which we postulate to be the result of heat associated with magma injection and subsequent localized contact metamorphism. To our knowledge, such a relation between mafic melt-impregnation of peridotite and metamorphism (of peridotite) has not previously been established in general and specifically for the Atlantis Massif peridotite. Closure temperatures of 440–731 °C of metamorphosed Cr–spinel approximate greenschist to amphibolite facies metamorphic conditions.
Higher-power harmonic maps and sections
Authors: Ramachandran A. , Wood C. M. 
Published: November 2022

AbstractThe variational theory of higher-power energy is developed for mappings between Riemannian manifolds, and more generally sections of submersions of Riemannian manifolds, and applied to sections of Riemannian vector bundles and their sphere subbundles. A complete classification is then given for left-invariant vector fields on three-dimensional unimodular Lie groups equipped with an arbitrary left-invariant Riemannian metric.
Computational indeterminacy and explanations in cognitive science
Authors: Papayannopoulos Philippos , Fresco Nir , Shagrir Oron 
Published: November 2022

AbstractComputational physical systems may exhibit indeterminacy of computation (IC). Their identified physical dynamics may not suffice to select a unique computational profile. We consider this phenomenon from the point of view of cognitive science and examine how computational profiles of cognitive systems are identified and justified in practice, in the light of IC. To that end, we look at the literature on the underdetermination of theory by evidence and argue that the same devices that can be successfully employed to confirm physical hypotheses can also be used to rationally single out computational profiles, notwithstanding IC.
Association Between Maternal Factors and Risk of Congenital Heart Disease in Offspring: A Systematic Review and Meta-Analysis
Authors: Wu Lina , Li Na , Liu Yong 
Published: November 2022

Abstract
Introduction
This study aimed to summarize the evidence describing the relationship between maternal factors during gestation and risk of congenital heart disease (CHD) in offspring.

Methods
PubMed, EMBASE, and the Cochrane Library were searched for potentially relevant reports from inception to May 2021. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) calculated by the random-effects model were used to evaluate the association between maternal factors and CHD risk.

Results
There was a significant association between CHD risk and obesity in pregnancy (OR 1.29, 95% CI 1.22–1.37; P < 0.001), smoking in pregnancy (OR 1.16, 95% CI 1.07–1.25; P < 0.001), maternal diabetes (OR 2.65, 95% CI 2.20–3.19; P < 0.001), and exposure of pregnant women to organic solvents (OR 1.82, 95% CI 1.23–2.70; P = 0.003). No correlations were revealed between CHD susceptibility and advanced maternal age (OR 1.04, 95% CI 0.96–1.12; P = 0.328), underweight (OR 1.02, 95% CI 0.96–1.08; P = 0.519), alcohol intake in pregnancy (OR 1.08, 95% CI 0.95–1.22; P = 0.251), coffee intake (OR 1.18, 95% CI 0.97–1.44; P = 0.105), and exposure to irradiation (OR 1.80, 95% CI 0.85–3.80; P = 0.125).

Discussion
Maternal factors including maternal obesity, smoking in pregnancy, maternal diabetes and exposure to organic solvents might predispose the offspring to CHD risk.
A multicentre observational study of the prevalence, management, and outcomes of subsegmental pulmonary embolism
Authors: Armitage Michael N , Mughal Aishah Z , Huntley Christopher C , Lasserson Daniel , Newnham Michael 
Published: November 2022

Abstract
Background
The incidence of subsegmental pulmonary embolism (SSPE) has increased with improvements in imaging technology. There is clinical equipoise for SSPE treatment, with conflicting evidence of improved mortality or reduced venous thromboembolism recurrence with anticoagulation. SSPE studies have significant heterogeneity and often lack adequately matched disease comparator groups.

Objectives
To determine the prevalence, management, and outcomes of SSPE and compare them to patients with main, lobar, segmental, and no pulmonary embolism (PE).

Patients/Methods
All adult patients undergoing CT pulmonary angiography (CTPA) between 2013 and 2019, at 3 UK hospitals were included in the study. CTPA reports were text mined for language relating to PE, and then further manually screened for the presence and anatomical location of PE. Patient groups were propensity matched by age, sex, and year of CTPA prior to analysis. 3-month outcomes of major bleeding, VTE recurrence, and death were recorded.

Results
79 (3.8%) SSPEs were identified from 2,055 diagnoses of PE, and 14,300 CTPA reports. 44 (56%) of SSPEs were single artery emboli, 25 (32%) were multiple unilateral emboli, and 10 (13%) were multiple bilateral emboli. Mortality, VTE recurrence and major bleeding were similar at 3 months across all groups. 87.3% of SSPE imaging reports had an additional radiological diagnosis, with pleural effusion (30%), consolidation (19%), and cardiomegaly (19%) being the most common.

Conclusion
The prevalence of SSPE was 3.8% of all PEs and there were a substantial number of additional radiological findings in the SSPE group that may have accounted for their symptoms.
Construction and demolition waste recycling in developing cities: management and cost analysis
Authors: Ferronato Navarro , Fuentes Sirpa Rocio Clara , Guisbert Lizarazu Edith Gabriela , Conti Fabio , Torretta Vincenzo 
Published: November 2022

AbstractIn Bolivia, construction and demolition waste (CDW) is unmanaged. The current research implemented a CDW flow analysis and a cost assessment in the city of La Paz, aiming to compare future recycling scenarios. Lack of data is challenging; therefore, a review of 31 international studies has been conducted. Results report that the waste generation rate (WGR) of concrete residential buildings can be of about 91.9–113.3 kg m−2 for construction and about 867.2–1064.8 kg m−2 for demolition. In addition, positive correlation was found in national WGR with number of inhabitants and the GDP. By these results, it was estimated that about 271,051–349,418 tonnes of CDW are potentially generated yearly in La Paz, about two times more than the CDW projected by local authorities. By the scenarios analysis, it was estimated that 56.1–71.1% of the inert aggregates can be recycled. The cost of the system is estimated between 7.8 and 31.1 USD tCDW−1, for a total annual cost (20 years horizon) of about 2.3–9 million USD y−1 depending on the management scenario. In the best scenario, an average fee of less than 1% of the current costs of a flat in La Paz can be required, potentially affordable for the local economy. The most attractive scenario involves the source separation of recyclable materials and the hybrid organization of stationary and mobile recycling facilities. Results show that a CDW management can be implemented in La Paz to foster a circular economy in developing cities.
Perfectionism and Exercise Dependence: the Role of Basic Psychological Needs and Introjected Regulation
Authors: Biggs Daniel P. , Mallinson-Howard Sarah H. , Jowett Gareth E. , Hall Howard K. 
Published: November 2022

Abstract
Using a self-determination theory (SDT) framework, the aims of our study were to examine the perfectionism-exercise dependence relationships, and whether basic psychological needs and introjected regulation explained these relationships. Distance runners (n = 260, M age: = 42.41 years; SD: = 11.95 years, n = 144 female) completed measures of multidimensional perfectionism (self-oriented perfectionism (SOP); socially prescribed perfectionism (SPP)), basic psychological need satisfaction and thwarting, introjected regulation, and exercise dependence. Bivariate correlations revealed significant positive SOP-exercise dependence and SPP-exercise dependence relationships. Structural equation modelling suggested that, in combination, perfectionism, basic psychological need satisfaction/thwarting and introjected regulation accounted for large amounts of variance in exercise dependence. Tests of indirect effects showed that the SPP-exercise dependence relationship was mediated by basic psychological need thwarting and introjected regulation. Our findings suggest that while the SOP-exercise dependence relationship is more direct, need thwarting and introjected regulation represent a motivational signature of SPP and exercise dependence.
Preparation of polyurethane coating formulation based on dihydropyridine derivatives as an insecticide and antifungal additives for surface coating applications
Authors: Awad Mohamed A. , Saleh N. M. , Elsawy M. M. , Salem Salem S. , Abd El-Wahab H. 
Published: November 2022

AbstractPyridine derivatives are prepared and evaluated before being incorporated into polyurethane coating formulations to create antifungal and insecticidal coating compositions. Different analyses, including Fourier transform infrared (FTIR), mass, proton nuclear magnetic resonance (1HNMR), and carbon-13 nuclear magnetic resonance (13C NMR) spectra, were used to confirm the synthesized compounds. The material has been coated using a polyurethane coating mixture. Gloss, scratch resistance, flexibility, and adhesion are some of the coating attributes investigated; mechanical capabilities include impact resistance and shore hardness, and physicochemical properties such as chemical resistance of coated polyurethane (PU) samples are also investigated. PU coatings were applied to substrates to measure coating properties. The mechanical properties of the PU cast films were measured. The results of the experiments revealed that all PU coatings based on dihydropyridine derivatives had good scratch resistance which varied from > 1.5 to > 2 kg. While reducing gloss value varied from 65 to 85, there is no effect of the prepared compounds in the other mechanical test. These PU coatings have excellent chemical resistance except the alkali resistance as evidenced by their physicochemical properties. The observed antifungal and insecticide activities indicated that dry wood coated with PU based on dihydropyridine derivatives is promising for resistance to these insects and fungi, in comparison with the paint as blank. The results revealed that the inhibition zones diameter by compound 2 were 25.1 ± 0.69, 23.2 ± 0.94, 20.16 ± 0.62, 20 ± 0.80, and 18 ± 0.81 mm against A. terreus, A. niger, A. flavus, C. albicans, and A. fumigatus, respectively, whereas the inhibition zones (IZ) diameter by compound 3 were 22.56 ± 0.30, 21.03 ± 0.49, 21.03 ± 0.61, 21 ± 0.66, and 20 ± 0.78 mm versus A. niger, A. fumigatus A. flavus, C. albicans, and A. terreus, respectively. The ordering activity against insects increased as the dose concentration of the pyridine derivatives was increased.
How much does a forensic autopsy cost in Spain?
Authors: Martín-Cazorla Fernando , Ramos-Medina Valentín , Rubio-Lamia Leticia , Santos-Amaya Ignacio , Jódar-Sánchez Francisco 
Published: November 2022

Abstract
Introduction and objectives
The autopsy is considered the gold standard in death investigation. Performing an autopsy requires human and material resources that must be programmed in order to meet the demands of the judicial system. However, as far as we know, the cost of forensic autopsy in Spain has not been determined. Thus, the aim of this study was to estimate the cost of a standard autopsy in order to organise Forensic Pathology Services more efficiently.

Material and methods
A micro-cost analysis was carried out. The nominal group technique was applied using a panel of 10 forensic experts in order to identify and quantify the resources associated with a forensic autopsy.

Results
The results showed that analysis and studies are the most important item in the total cost (54.7%), followed by staff (20.5%), preservation of body (14%), single-use products (7%), equipment and stock (1.6%), cleaning and disinfection (1.5%), facilities maintenance (0.5%) and IT (0.2%).

Conclusions
The total cost of a standard autopsy was €1501.45, which is lower than the European average. This study is the first in Spain to calculate the unit price of a forensic autopsy by means of micro-cost analysis. This may help to address the way forensic pathology centres are organised at different levels of complexity.