bluuebunny/crossref_metadata_2025_split huggingface dataset:
SOME ASPECTS OF BILE PHYSIOLOGY IN NORM AND IN PATHOLOGY
Authors: Родионов Геннадий Георгиевич , Успенский Юрий Павлович , Фоминых Юлия Александровна , Наджафова Кямаля Низамитдиновна , Искалиева Аделя Руслановна , Кощеев Антон Викторович , Шантырь Игорь Игнатьевич , Светкина Екатерина Владимировна 
Published: November 2022

В данной статье обсуждается, каким составом и свойствами обладает желчь в нормальных физиологических условиях, как протекают сложные процессы синтеза и рециркуляции желчных кислот - важнейшего компонента желчи, и как меняются состав и свойства желчи при желчнокаменной болезни. В статье также приведены данные оригинального исследования, в котором впервые определены абсолютные значения содержания желчных кислот в пузырной желчи пациентов с желчнокаменной болезнью методом хромато -масс -спектрометрии.
This article discusses the composition and properties of bile in normal physiological conditions, how the complex processes of synthesis and recycling of bile acids - the most important component of bile - proceed, and how the composition and properties of bile change in cholelithiasis. The article also presents data from an original study in which the absolute values of the content of bile acids in the cystic bile of patients with cholelithiasis by chromatography -mass spectrometry were determined for the first time.
Karakteristik Tafsir fi Zhilal Al-Qur’an
Authors: Muhammad Zaidi 
Published: November 2022

Abstrac
Tafsir fi Zhilal Quran was written in the range of 1952 to 1965. He had time to revise the first thirteen juz of his interpretation during his long detention1. This interpretation led Sayid Qutub to explore the various moral messages of Islam that were conveyed through Muhammad's treatises, which strengthened faith and could provide a perfect ideological foundation. It was so phenomenal that Sayid Qutub wrote a fi dzilal al-quran interpretation, with its unique methods and characteristics, rich in literary and social language in his dakwa, inviting and inviting in a beautiful language style.Sayid qutub can complete his Tafsir in prison with enthusiasm and enthusiasm in writing his tafsir, with the aspiration to provide the best legacy for future generatio

Abstrak
Tafsir fi Zhilal Quran ditulis dalam rentang antara tahun 1952 sampai tahun 1965. Beliau sempat merivisi ketiga belas juz pertama tafsirnya semasa penahanannya yang panjang.1 Tafsir ini membawa Sayid Qutub menjelajahi berbagai pesan moral Islam yang diemban melalui risalah Muhammad Saw, menguatkan Iman dan dapat menjadikan fondasi ideologi yang sempurna. Begitu fenomenalnya Sayid Qutub menulis tafsir fi dzilal al-quran, dengan metode dan karakteristiknya yang khas kaya akan bahasa satra dan social dalam dakwanya, menyeru dan mengajak dengan gaya bahasa yang indah. Sayid qutub dapat menyelesaikan Tafsirnya dalam penjara dengan antusias dan semangat dalam menulis karya tafsirnya, dengan cita-cita untuk memberikan waritsan yang terbaik untuk generasi yang akan datang.

1 Muhammad Zhirzin, Jihad menurut Sayid Qutub, (Solo, Ira Intermedia, 2001) h.134
ASPS Exhibits Anti‐Rheumatic Effects by Reprogramming Gut Microbiota and Increasing Serum γ‐Glutamylcysteine Level
Authors: Liu Ang , Zhang Min , Wu Yanglin , Zhang Chenhui , Zhang Qin , Su Xinlin , Zhu Xu , Shi Weidong , Liu Jiangyun , Zhang Yang , Huang Cheng , Yan Zhaowei , Lin Jun 
Published: November 2022

AbstractRheumatoid arthritis (RA) is an essential cause of labor loss and disability for people worldwide. Acanthopanax senticosus polysaccharide (ASPS) is one of the most important active components from A. senticosus, which exhibits various pharmacological activities such as antioxidation and immunomodulation. However, no studies have reported the application of ASPS in treating RA. This study aims to investigate the therapeutic effect of ASPS on RA and reveal its underlying mechanism. The potential therapeutic effect of ASPS against RA is initially verified in this study using the collagen‐induced arthritis model. Moreover, the protective benefits of ASPS are transmitted through the fecal microbiota and blocked by simultaneous antibiotic cocktail treatment, indicating that gut microbiota may be correlated with ASPS. The 16S rRNA sequencing using feces samples and untargeted UPLC‐MS metabolomics using serum samples further reveal that ASPS reprograms the arthritic progression triggered dysbiosis, enhances the expression of γ‐glutamylcysteine (GGC) synthetase, and enriches the serum concentration of GGC. Furthermore, metabolites GGC is found to be able to effectively interrupt NLRP3 inflammasome activation via inhibiting ASC nucleation and therefore attenuate inflammatory arthritis. Taken together, this work highlights ASPS's therapeutic potential against RA, which mainly exhibits its effects via modulating gut microbiota and regulating GGC production.
Hierarchically structural polyacrylonitrile/MIL‐101(Cr) nanofibrous membranes with super adsorption performance for indoxyl sulfate
Authors: Ding Weihong , Ding Siping , Meng Zheyi , Wang Xuefen 
Published: November 2022

AbstractExcess protein‐bound uremic toxins (such as indoxyl sulfate [IS]) in the blood could aggravate chronic kidney disease and also predispose to serious cardiovascular disease. In this study, we constructed a novel IS adsorbent polyacrylonitrile/MIL‐101(Cr) (PAN‐M) nanofibrous membrane with high adsorption capacity and ultra‐fast sorption rate for IS. The porous metal–organic framework MIL‐101(Cr) were embedded in PAN nanofibers by electrospinning as an adsorbent for easy recovery. It was found that MIL‐101(Cr) had a strong electrostatic effect on the SO3− of IS and could reach the adsorption equilibrium within 5 min. Notably, MIL‐101(Cr) showed an extremely high adsorption capacity (~170 mg/g) for IS. The MIL‐101(Cr) loading of prepared PAN‐M nanofibrous membrane was optimized at 60 wt% and the optimal PAN‐M60 exhibited an appreciable IS adsorption capacity (103 mg/g). The removal of IS was enhanced from 35.4% to 62.5% during hemodialysis by using PAN‐M60 as adsorbent immersed in dialysate. This efficient adsorption performance can greatly reduce the consumption of dialysate and may shorten the hemodialysis time. This work would provide a fresh perspective on the development of MOF‐based adsorbents to improve hemodialysis therapies.
Assessing the potential for restoring freshwater mussels to urban streams
Authors: Bukaveckas Paul A. , Ryan John‐Reid , Mair Rachel 
Published: November 2022

Abstract

Field trials were conducted to assess the potential for stocking native unionid mussels in urban streams of the Chesapeake Bay catchment. Juvenile, hatchery‐raised mussels were placed in enclosures at five urban streams (two restored and three unrestored) and two nearby rural streams. Adult mussels were translocated to two restored urban streams. Mussel growth and survivorship were assessed at the stream sites and for individuals maintained at hatchery ponds.
At all sites, water quality conditions were generally suitable for mussels with respect to temperature, pH, and dissolved oxygen. Food resources, as indicated by the quantity and quality of suspended and benthic particulate matter, were higher among rural sites and lower in unrestored urban streams.
Positive growth rates were observed at all sites, among both juveniles (caged) and translocated adults. Mussel fatty acid profiles were generally similar among sites, except for docosahexaenoic acid (DHA), which was lower among stocked mussels relative to mussels maintained at the hatchery.
Among the unrestored urban streams, the frequent occurrence of high discharge events resulted in burial and downstream loss of enclosures. At restored urban streams and rural streams, the washout effects were less severe. Apart from washout effects, mortality, as indicated by the presence of dead mussels, was low (<10%).
Overall, rural and restored urban streams provided suitable conditions for stocking native mussels, whereas in unrestored urban streams, bed and bank instability during high discharge events resulted in a high attrition of mussels. Conservation efforts may be aided by the consideration of mussel habitat needs in the design of stream restoration projects. The inclusion of mussel stocking efforts in urban stream restoration projects has the potential to facilitate stream recovery, expand and bring greater attention to mussel conservation efforts, and garner public support for the preservation of stream health in urban areas.
Levodopa responsiveness and white matter alterations in Parkinson's disease: A DTI‐based study and brain network analysis: A cross‐sectional study
Authors: Du Juncong , Zhou Xuan , Liang Yi , Zhao Lili , Dai Chengcheng , Zhong Yuke , Liu Hang , Liu Guohui , Mo Lijuan , Tan Changhong , Liu Xi , Chen Lifen 
Published: November 2022

AbstractBackgroundPatients with Parkinson's disease (PD) present various responsiveness to levodopa, but the cause of such differences in levodopa responsiveness is unclear. Previous studies related the damage of brain white matter (WM) to levodopa responsiveness in PD patients, but no study investigated the relationship between the structural brain network change in PD patients and their levodopa responsiveness.MethodsPD patients were recruited and evaluated using the Unified Parkinson's Disease Rating Scale (UPDRS). Each patient received a diffusion tensor imaging (DTI) scan and an acute levodopa challenge test. The improvement rate of UPDRS‐III was calculated. PD patients were grouped into irresponsive group (improvement rate < 30%) and responsive group (improvement rate ≥ 30%). Tract‐based spatial statistics (TBSS), deterministic tracing (DT), region of interest (ROI) analysis, and automatic fiber identification (AFQ) analyses were performed. The structural brain network was also constructed and the topological parameters were calculated.ResultsFifty‐four PD patients were included. TBSS identified significant differences in fractional anisotropy (FA) values in the corpus callosum and other regions of the brain. DT and ROI analysis of the corpus callosum found a significant difference in FA between the two groups. Graph theory analysis showed statistical differences in global efficiency, local efficiency, and characteristic path length.ConclusionPD patients with poor responsiveness to levodopa had WM damage in multiple brain areas, especially the corpus callosum, which might cause disruption of information integration of the structural brain network.
The mere possession effect of shareable digital coupons: The mediating role of anticipated self‐enhancement
Authors: Zhang Sha , De Vries Eline L.E. , Ding Aihui 
Published: November 2022

AbstractShareable digital coupons have emerged as a new marketing strategy. Prior literature on shareable coupons assumes that shareable coupons can play a role only after they have been shared with others. Surprisingly, we theorize that shareable coupons can come into play as early as when consumers merely possess them, even before consumers share them with others, an effect that precedes the effect of the actual coupon sharing. In this research, we show that the mere possession of shareable digital coupons (not necessarily the actual sharing) is able to induce anticipated self‐enhancement among consumers. Hence shareable digital coupons are more effective than non‐shareable digital coupons, and the effect is most pronounced among consumers with high image concerns. The higher coupon effectiveness of shareable digital coupons is reflected in consumers' greater urge/intention to acquire the coupon, intention to revisit, willingness to spend, as well as in firm's sales increase when products are promoted with shareable instead of non‐shareable digital coupons. Our work contributes to the literature on shareable coupons, the mere possession effects, anticipated self‐enhancement, and other‐rewarding promotions, and is of important managerial value given the ease with which the shareability feature can be added to coupons.
Oral propranolol and topical timolol in the treatment of post‐burn pyogenic granuloma: Two cases and a review of the literature
Authors: Ebrahimi Zahra , Mahdi Zeinab , Khairi Ali Asghar , Behrangi Elham , Zare Armaghan Gharehaghaji , Dehghani Abbas , Goodarzi Azadeh 
Published: November 2022

AbstractTwo cases of pyogenic granulomas in burned skin were presented, a 17‐month‐old boy and a 7‐year‐old girl, being given oral propranolol and topical timolol. Both cases showed lesions improvement with no adverse effects, suggesting that beta‐blocker therapy may have a positive impact on the treatment of pyogenic granuloma after burns.
Sulfur‐doped hard carbon hybrid anodes with dual lithium‐ion/metal storage bifunctionality for high‐energy‐density lithium‐ion batteries
Authors: Cho Sungmin , Hyun Jong Chan , Ha Son , Choi Yeonhua , Seong Honggyu , Choi Jaewon , Jin Hyoung‐Joon , Yun Young Soo 
Published: November 2022

AbstractBifunctional hybrid anodes (BHAs), which are both a high‐performance active host material for lithium‐ion storage as well as a guiding agent for homogeneous lithium metal nucleation and growth, exhibit significant potential as anodes for next‐generation high‐energy‐density lithium‐ion batteries (LIBs). In this study, sulfur‐doped hard carbon nanosphere assemblies (S‐HCNAs) were prepared through a hydrothermal treatment of a liquid organic precursor, followed by high‐temperature thermal annealing with elemental sulfur for application as BHAs for LIBs. In a carbonate‐based electrolyte containing fluoroethylene carbonate additive, the S‐HCNAs showed high lithium‐ion storage capacities in sloping as well as plateau voltage sections, good rate capabilities, and stable cyclabilities. In addition, high average Coulombic efficiencies (CEs) of ~96.9% were achieved for dual lithium‐ion and lithium metal storage cycles. In the LIB full‐cell tests with typical NCM811 cathodes, the S‐HCNA‐based BHAs containing ~400 mA h g−1 of excess lithium led to high energy and power densities of ~500 W h kg−1 and ~1695 W kg−1, respectively, and a stable cycling performance with ~100% CEs was achieved.
Chemistry, Medicine, and Gold‐Making: Tycho Brahe, Helwig Dieterich, Otto Tachenius, and Johann Glauber
Authors: Wentrup Curt 
Published: November 2022

Abstract17th century chemistry was concerned largely with iatrochemistry (medicinal chemistry) and the transmutation of metals, especially with the purpose of making gold. Thus, Johann Rudolph Glauber made a living making and selling chemicals such as nitric acid and medicaments such as aurum potabile (drinkable gold), but he also believed in the transmutation or “improvement” of metals and the “augmentation” of gold, and he sold recipes for such processes. This perspective aims to provide a snapshot of the range of 17th century chemistry by analysis of the efforts of four representatives to make drugs, chemicals, and gold. It will be concluded that early modern chemists were unable to break out from the conceptual doctrines imposed by Aristotle and Paracelsus, which made transmutation perfectly logical. No further scientific advance could be made until the idea that all things are composed of the same basic constituents was abandoned in favour of the atomic theory.
Design of an RF output Class JJ−1 Doherty power amplifier using post‐matching varactor diodes for configurable IoT transmitters
Authors: Kumar Rajesh , Kumar Sachin , Kanaujia Binod Kumar 
Published: November 2022

SummaryIn this paper, a Doherty power amplifier (DPA) based on Class‐J power amplifier (PA) and Class‐J−1 PA is proposed for configurable Internet of things (IoT) transmitters. A post‐matching structure is used to achieve wider bandwidth performance, high efficiency, and power gain flatness. Different drain biases on the main and peaking devices are used to perform asymmetric operations. The proposed DPA structure achieves 62.4% power‐added efficiency (PAE) with a maximum output range of 37.38–38.20 dBm for the frequency band of 5.1–5.8 GHz and a power gain range of 13.24–12.24 dB. It has a maximum drain efficiency of 42.7%–51.5% at a back‐off power level of 9 dB. In order to validate the linearity of the proposed design, an analysis of the adjacent channel leakage ratio (ACLR) for various gate‐biased voltage operations is performed. The microchip occupies a compact die area of 2.1 mm × 1.2 mm, which is fabricated with GaAs 0.25 μm PHEMT to validate the enhanced broadband characteristics of the proposed configuration. Compared to the existing DPAs, the proposed DPA exhibits higher efficiency, output power, and compact size.
Pathologist‐performed ultrasound‐guided fine needle aspiration biopsies of extrathyroidal sites: An observational study
Authors: Kliassov Evelyna George , McKenzie David Robert , Dash Rajesh Chandra , Jiang Xiaoyin , Jones Claudia Kay , Foo Wen‐Chi 
Published: November 2022

AbstractBackgroundPathologist‐performed ultrasound‐guided fine needle aspiration (USFNA) biopsies have become an increasingly important component of the interventional cytopathologist's toolbox. However, its application varies between institutions, and there is limited literature describing its performance characteristics when utilized in extrathyroidal sites. Here we review our institutional experience within our pathologist‐run FNA clinic.MethodsA retrospective review was conducted of pathologist‐performed USFNAs of extrathyroidal sites over a 9‐year period. Data collected included lesion site, size, patient age, patient gender, diagnostic category, and corresponding results from surgical resection when available. The diagnosis on surgical resection was considered the gold standard for determining discordance rates.ResultsA total of 143 pathologist‐performed USFNAs of extrathyroidal lesions were performed from October 2011 to October 2020. These encompassed a wide range of sites, with most biopsies from the head and neck. The mean recorded size was 2.2 cm, with a range of 0.6–6 cm. Larger lesions (over 2 cm) were more likely to be noted in challenging locations, demonstrate difficult features, or be cystic. Most (n = 133) biopsies were sufficient for diagnosis, with a non‐diagnostic rate of 7% (n = 10). Accuracy when compared to subsequent surgical resection was high, with sensitivity of 89%, specificity of 93%, positive predictive value of 94%, and negative predictive value of 87%.ConclusionOur experience supports that pathologist‐performed USFNA of extrathyroidal lesions—even those with challenging features—can result in excellent diagnostic yield and accuracy. The addition of USFNA to the interventional cytopathologists' repertoire can be a valuable tool to enhance patient care.
Self‐regulation profiles reflecting distinct levels of eating disorder and comorbid psychopathology in the adult population: A latent profile analysis
Authors: Eichler Janina , Schmidt Ricarda , Bartl Carl , Benecke Cord , Strauss Bernhard , Brähler Elmar , Hilbert Anja 
Published: November 2022

AbstractObjectivePrevious research showed that individuals with eating disorders (EDs) can be subtyped by their levels of psychopathology and self‐regulation abilities. However, nothing is known about whether self‐regulation abilities are solely suited to depict the heterogeneity in ED and comorbid psychopathology in nonclinical samples. Therefore, this study sought to explore self‐regulation profiles and their ability to discriminate ED, depression and anxiety disorders, and personality dysfunction in the adult population.MethodsWithin a German representative sample, N = 2391 adults (18–92 years) were examined using latent profile analysis to identify profiles based on established cognitive and emotional self‐regulation scales including attention control, cognitive reappraisal, and difficulties in identifying feelings. Profiles were validated with ED, depression, anxiety, and personality dysfunction measures.ResultsThe final solution selected as best balancing goodness of fit and interpretability included four profiles—High‐Functioning, Moderate‐Functioning, Dysregulated, and Alexithymic—with high explanatory power of R2 = .99. Profiles were characterized primarily by differences in difficulties in identifying feelings followed by differences in attention control and differed significantly regarding ED, depression and anxiety disorders, and personality dysfunction, with the Dysregulated profile showing the most unfavorable correlates.ConclusionsThis study uniquely revealed that low cognitive and emotional self‐regulation were indicators for ED, depression, anxiety, and personality dysfunction in the adult population. Future research should investigate whether the identified profiles predict the development of ED and comorbid psychopathology longitudinally.Public SignificanceIndividuals with eating disorders present with difficulties in cognitive and emotional self‐regulation, likely maintaining their symptoms. This representative study in the German adult population sought to build profiles based on cognitive and emotional self‐regulation that differed in eating disorder and comorbid psychopathology. We discuss the potential to detect individuals with elevated eating disorder and comorbid psychopathology based on the identified profiles in nonclinical settings.
Sprout microbial safety: A reappraisal after a quarter‐century
Authors: Fahey Jed W. , Smilovitz Burak Jack , Evans Doug 
Published: November 2022

AbstractThe World Health Organization estimates that each year one in 10 people worldwide falls ill after eating contaminated food, resulting in 600 million cases of foodborne diseases and 420,000 deaths. In the United States, the Centers for Disease Control estimates that 48 million people get sick from a foodborne illness, 128,000 are hospitalized, and 3000 die. A very small fraction of those illnesses is due to sprouts.Commercial green sprout production began in the early 1970s, but home‐sprouting has been practiced by small numbers of people for a very long time. Twenty‐five years ago, the US Food and Drug Administration investigated 50 reported outbreaks and 2600 cases of foodborne illness associated with contaminated sprouts. Since then, the promulgation of science‐based guidelines has led to laboratory (hold‐and‐release) testing mandates for the green‐sprout industry. Home‐sprouters have become better informed of potential hazards, and they now have safer raw materials and safety‐promoting supplies available to them, and a number of online communities that exchange information rapidly. Safe microgreens (“large sprouts”) production has also grown considerably since then.Data based on more than two decades of surveillance support the thesis that sprouts are not only highly nutritious, but also very safe when responsibly produced. Both the need to select for appropriate seed “genetics” and “phenotype” and the need to test and certify seed supply for both commercial sprouters and home‐sprouters is paramount to serving a more informed and progressive sprouting public (both consumers of commercially sprouted seeds and home‐sprouters).