bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surrogate neutralization responses following severe acute respiratory syndrome coronavirus 2 vaccination in people with HIV: comparison between inactivated and mRNA vaccine
Authors: Wong Ngai Sze , Wong Bonnie C.K. , Chan Jacky M.C. , Wong Ka Hing , Tsang Owen T.Y. , Mok Chris K.P. , Hui David S.C. , Lee Shui Shan , Chan Denise P.C. 
Published: April 2022

Objective:
People with HIV (PWH) co-infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are at higher odds of severe diseases. Whereas the immunogenicity of mRNA vaccine and adenovirus-vectored vaccine was similar between PWH in stable condition and healthy adults, the effects of inactivated vaccines are not known.

Design:
Prospective longitudinal observational study in real-world setting.

Methods:
Adult PWH in care and planning to receive either inactivated (day 0 and day 28) or mRNA-based (day 0 and day 21) vaccine against SARS-CoV-2 were recruited, with blood samples collected over 6 months for surrogate virus neutralization test (sVNT). Demographic and clinical data including age, sex, CD4+ cell count, and suppressed viral load (SVL) status were transcribed for analyses, by simple and multivariable linear regression models, and multivariable linear generalized estimating equations (GEE).

Results:
A total of 611 HIV patients, 91% male patients, were recruited, of whom 423 and 184 have received mRNA-based and inactivated vaccine, respectively. The seroconversion rate was 99% for mRNA-based vs, 86% for inactivated vaccine [odds ratio (OR) = 21.56, P = 0.004]. At 6 months, mRNA-based vaccine continued to give a higher response (94 vs. 57%, P < 0.001). The temporal pattern varied between the two vaccines. By GEE, mRNA-based vaccine (B = 40.59, P < 0.001) and latest SVL status (B = 10.76, P = 0.01) were positively associated with sVNT level, but not latest CD4+ cell count.

Conclusion:
In HIV patients, inactivated vaccine gave a lower peak and shorter duration of sVNT responses compared with mRNA vaccine. The results suggested that different strategies may be needed in boosting the immunity in anticipation of the emergence of variants in the community.
High efficacy of switching to bictegravir/emtricitabine/tenofovir alafenamide in people with suppressed HIV and preexisting M184V/I
Authors: Sax Paul E. , Andreatta Kristen , Molina Jean-Michel , Daar Eric S. , Hagins Debbie , Acosta Rima , D’Antoni Michelle L. , Chang Silvia , Martin Ross , Liu Hui , Blair Christiana , McNicholl Ian , Gallant Joel , Collins Sean E. , Martin Hal , White Kirsten L. 
Published: April 2022

Objective:
We investigated the prevalence of preexisting M184V/I and associated risk factors among clinical trial participants with suppressed HIV and evaluated the impact of M184V/I on virologic response after switching to bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF).

Design:
Participant data were pooled from six clinical trials investigating the safety and efficacy of switching to B/F/TAF in virologically suppressed people with HIV.

Methods:
Preexisting drug resistance was assessed by historical genotypes and/or baseline proviral DNA genotyping. Virologic outcomes were determined by last available on-treatment HIV-1 RNA. Stepwise selection identified potential risk factors for M184V/I in a multivariate logistic regression model.

Results:
Altogether, 2034 participants switched treatment regimens to B/F/TAF and had follow-up HIV-1 RNA data, and 1825 of these participants had baseline genotypic data available. Preexisting M184V/I was identified in 182 (10%), mostly by baseline proviral DNA genotype (n = 167). Most substitutions were M184V (n = 161) or M184V/I mixtures (n = 10). Other resistance substitutions were often detected in addition to M184V/I (n = 147). At last on-treatment visit, 98% (179/182) with preexisting M184V/I and 99% (2012/2034) of all B/F/TAF-treated participants had HIV-1 RNA less than 50 copies/ml, with no treatment-emergent resistance to B/F/TAF. Among adult participants, factors associated with preexisting M184V/I included other resistance, black race, Hispanic/Latinx ethnicity, lower baseline CD4+ cell count, advanced HIV disease, longer duration of antiretroviral therapy, and greater number of prior third agents.

Conclusion:
M184V/I was detected in 10% of virologically suppressed clinical trial participants at study baseline. Switching to B/F/TAF demonstrated durable efficacy in maintaining viral suppression, including in those with preexisting M184V/I.
Heat transport in Rayleigh–Bénard convection with linear marginality
Authors: Wen Baole , Ding Zijing , Chini Gregory P. , Kerswell Rich R. 
Published: April 2022

Recent direct numerical simulations (DNS) and computations of exact steady solutions suggest that the heat transport in Rayleigh–Bénard convection (RBC) exhibits the classical1/3scaling as the Rayleigh numberRa→∞with Prandtl number unity, consistent with Malkus–Howard’s marginally stable boundary layer theory. Here, we construct conditional upper and lower bounds for heat transport in two-dimensional RBC subject to a physically motivated marginal linear-stability constraint. The upper estimate is derived using the Constantin–Doering–Hopf (CDH) variational framework for RBC with stress-free boundary conditions, while the lower estimate is developed for both stress-free and no-slip boundary conditions. The resulting optimization problems are solved numerically using a time-stepping algorithm. Our results indicate that the upper heat-flux estimate follows the same5/12scaling as the rigorous CDH upper bound for the two-dimensional stress-free case, indicating that the linear-stability constraint fails to modify the boundary-layer thickness of the mean temperature profile. By contrast, the lower estimate successfully captures the1/3scaling for both the stress-free and no-slip cases. These estimates are tested using marginally-stable equilibrium solutions obtained under the quasi-linear approximation, steady roll solutions and DNS data.This article is part of the theme issue ‘Mathematical problems in physical fluid dynamics (part 1)’.
Editorial: Mathematical problems in physical fluid dynamics: part I
Authors: Goluskin D. , Protas B. , Thiffeault J.-L. 
Published: April 2022

Fluid dynamics is a research area lying at the crossroads of physics and applied mathematics with an ever-expanding range of applications in natural sciences and engineering. However, despite decades of concerted research efforts, this area abounds with many fundamental questions that still remain unanswered. At the heart of these problems often lie mathematical models, usually in the form of partial differential equations, and many of the open questions concern the validity of these models and what can be learned from them about the physical problem. In recent years, significant progress has been made on a number of open problems in this area, often using approaches that transcend traditional discipline boundaries by combining modern methods of modelling, computation and mathematical analysis. The two-part theme issue aims to represent the breadth of these approaches, focusing on problems that are mathematical in nature but help to understand aspects of real physical importance such as fluid dynamical stability, transport, mixing, dissipation and vortex dynamics.
This article is part of the theme issue ‘Mathematical problems in physical fluid dynamics (part 1)’.
A hybrid approach to supporting physical-change-based renewal projects selection decisions in high-density city: a case study of Chongqing
Authors: Chen Yizhong , Zhuang Taozhi , Liu Guiwen 
Published: April 2022

Purpose The aims of this paper is to establish an appropriate physical-change-based renewal (PCBR) projects selection mechanism capable of selecting the combination of the PCBR projects that can make up an integrated urban renewal program in high-density cities.Design/methodology/approach The research design follows a sequential integrated methodology that combines the calculation algorithms of Fuzzy Analytic Network Process (Fuzzy-ANP) with Zero-One Goal Programming (ZOGP) to support decisions for the selection of PCBR projects. In the first phase, general criteria for assessing the sustainability performance of PCBR projects were collected from relevant literature. In the second phase, the Fuzzy-ANP was used to identify the priority weights of the candidate projects through clarifying the interdependent degree between the criteria and candidate projects. Finally, ZOGP method was selected as a predetermined number of PCBR projects among candidate projects.Findings The feasibility and effectiveness of this hybrid approach is then verified in a case study of Yuzhong District, Chongqing in China. The results of this study indicate that the integrated method is capable of directing the decision maker toward the best compromising solution of PCBR program that can achieve the maximization of sustainable benefits and allocate limited resources most efficiently.Originality/value The novelty of this paper consists in combining the algorithms of the Fuzzy-ANP method with those of the ZOGP model that serves as an effective analysis tool to address practical decision problems. This is the first hybrid algorithms to make PCBR projects selection decision that reach the maximization of the sustainable benefits, both in economic and socio-environmental terms.
Forecasting internet diffusion in Italy based on the “.it” domain names metrics
Authors: Serrecchia Michela 
Published: April 2022

Purpose
The aim of this study is to examine the trend over time of the demand for .it domain names.This study first assesses whether there is a phase of growth and expansion or at a point of saturation. Second, this research can be useful also to compare researches that have considered other internet metrics and other models.

Design/methodology/approach
This paper describes the forecasting methods used to analyze the internet diffusion in Italy. The domain names under the country code top-level domain “.it” have used as metrics. To predict domain names .it the seasonal auto regressive integrated moving average (SARIMA) model and the Holt-Winters (H-W) methods have been used.

Findings
The results show that, to predict domain names .it the SARIMA model is better than the H-W methods. According to the findings, notwithstanding the forecast of a growth in domain names, the increase is however limited (about 3%), tending to reach a phase of saturation of the market of domain names .it.

Originality/value
In general many authors have studied internet diffusion applying statistical models that follow an S-shaped behavior. On the other hand, the more used diffusion models that follow an S-shape not always provide an adequate description of the Internet growth pattern. To achieve this goal, this paper demonstrates how the time series models, in particular SARIMA model and H-W models, fit well in explaining the spread of the internet.
OTT platforms resilience to COVID-19 – a study of business strategies and consumer media consumption in India
Authors: Sharma Kavita , Lulandala Emmanuel Elioth 
Published: April 2022

Purpose
COVID-19 preventive measures disrupted the media and entertainment business ecosystem, increased over the top (OTT) consumption, brought new OTT players, thus increased competition, and shaped consumer behaviour and habits. Despite this knowledge, in-depth insights into OTT's consumer behaviour, new usage habit and strategies used by subscription-based OTT platforms to maintain resilience during the COVID-19 pandemic are unknown. This paper aims to fill the two gaps in the extant OTT literature.

Design/methodology/approach
This study used Eisenhardt's multiple case studies approach to derive the strategies used by the top-performing subscription-based OTT platforms in India. Moreover, a purposive semi-structured Google survey was used to explore consumers' OTT experience during the pandemic. This study analysed data using NVivo 12 (survey) and MS Excel 2010 (case studies).

Findings
This study derived seven resilient OTT strategies; competitive low pricing, enhancing customer experience, launching innovative service plans, content localisation, strategic collaboration, flexibility in technology adoption and proactive sales promotion. Consequent to adopting these strategies, consumers' usage of OTT evolved from occasional to habitual. Convenience, ease of accessibility, risk of contracting COVID-19, variety and quality of content, online reviews and affordability drive consumer preference for OTT. Also, this study revealed consumers' varied OTT experiences.

Originality/value
The contribution is two-fold; the derived strategies for maintaining resilience and the in-depth insights into habit formation and consumer behaviour during and after the COVID-19 pandemic. This study is valuable for media and entertainment stakeholders like streaming service providers, OTT services, cable operators, etc.
Interpreting emotional insights and behavioral intentions of travelers based on push and pull motivations during Covid-19
Authors: Pattanayak Lopamudra , Jena Lalatendu Kesari , Sahoo Kalpana 
Published: April 2022

PurposeThe purpose of this study is to interpret the travel motivations of travelers in India amidst the coronavirus pandemic. It takes into consideration the “push and pull motivational forces” of travelers, translating their emotional insights and behavioral intentions based on these forces.Design/methodology/approachThe research design consists of a mixed-mode approach of study inclusive of semi-directive interviews of 231 participants from India. The statistical computing language R has been used to conduct sentiment analysis.FindingsThe results obtained show that “fear” and “sadness” are the prevalent emotions among the travelers due to the coronavirus outbreak based on the results of sentiment analysis. While, positive emotions of “trust” and “joy” were missing comparatively. These emotions along with other traveling constraints amidst coronavirus acted as the intrinsic push factors and extrinsic pull factors affecting their travel motivations.Originality/valueThe study throws light on the practical and theoretical implications of such travel motivations, emotions affecting these motivations, leading to travelers' behavioral intentions. The work adds to the limited works of tourism literature amidst the coronavirus outbreak.
Impulse purchases during emergency situations: exploring permission marketing and the role of blockchain
Authors: Nigam Achint , Behl Abhishek , Pereira Vijay , Sangal Shreya 
Published: April 2022

PurposeThe paper explores how consumer behavior for purchasing impulse products changed in the complex and disruptive (emergency) situation of the COVID-19 pandemic when the customer is shopping in-home and not visiting the offline stores in an emerging economy context. This paper further explores how digital transformations like the use of blockchain technology can aid offline/omnichannel retailers in reviving sales via permission marketing for impulse products.Design/methodology/approachThe authors followed a qualitative research design and conducted 24 personal interviews with millennials and 15 interviews with offline/omnichannel retailers from an emerging economy. The data collected were analyzed using the thematic analysis procedure.FindingsThe authors discuss their findings under three themes – customers' conscious impulse buying during the pandemic, customers' unconscious impulse buying during the pandemic, and a viable solution for retailers in response to the pandemic.Practical implicationsThe authors suggest that marketers primarily from an offline/omnichannel store should adapt to permission marketing and use technologies like blockchain for the digital transformation of their marketing strategies. Doing so can help offline retailers minimize future damages in the retail sector during emergency situations.Originality/valueThis paper is one of the first that explores how impulse – pure, suggestion, planned and reminder – purchases got affected during the COVID-19 pandemic disruptions in an emerging economy. This paper is also one of the first to explore the role of permission marketing and digital transformation by the use of blockchain in helping offline retailers in forming swift trust and practice trust-based marketing.
The story of a model restorative school: creative response to conflict at MS 217 in Queens, NY
Authors: Prutzman Priscilla , Roberts Elizabeth , Fishler Tara , Jones Tricia 
Published: April 2022

PurposeRestorative practice programs in the USA and Western elementary and secondary schools have been the focus of intensive, large scale field research that reports positive impacts on school climate, pro-social student behavior and aggressive behavior. This paper aims to contribute to a gap in the research by reporting a case study of transformation of an urban middle school in a multi-year implementation of restorative practices.Design/methodology/approachThis paper reports how Creative Response to Conflict (CRC) supported the transformation of Middle School 217, in Queens, NY, from a school with one of the highest suspension rates in New York City to a model restorative school. CRC’s model, which incorporates the themes of cooperation, communication, affirmation, conflict resolution, mediation, problem-solving, bias awareness, bullying prevention and intervention, social-emotional learning and restorative practices, helped shift the perspective and practice of the entire school community from punitive to restorative.FindingsImplementation of a full school advisory program using restorative circles for all meetings and classes and development of a 100% respect program committing all school community members to dignified and respectful treatment aided the transformation. Key to MS 217’s success was the collaboration of multiple non-profit organizations for provision of peer mediation training, after-school follow-up work, staff coaching and preventative cyberbullying training through the Social Media-tors! Program.Research limitations/implicationsChallenges to the restorative practices implementation are reviewed with attention to the implementation online during COVID-19.Originality/valueNext steps in the program post-COVID are articulated as a best practice model for other schools interested in adopting MS 217’s commitment, creativity and community-building to become a model restorative school.
Alexithymia, social inhibition, affectivity, and knowledge hiding
Authors: Kmieciak Roman 
Published: April 2022

Purpose
This paper aims to examine the impact of adverse personality traits (alexithymia, social inhibition, negative affectivity) and supervisor knowledge hiding on individual knowledge hiding. This study also explores the moderating role of positive affectivity.

Design/methodology/approach
Partial least squares path modeling and data collected from 518 Polish employees with higher education and extensive professional experience recruited via an Ariadna survey panel were used to test the research hypotheses.

Findings
Two dimensions of alexithymia were considered: difficulty identifying feelings (DIF) and difficulty describing feelings (DDF). DIF has a direct impact on individual hiding, whereas DDF has an indirect impact, via social inhibition. Negative affectivity is a predictor of social inhibition, which enhances knowledge hiding. Positive affectivity slightly weakens the positive and strong effect of supervisor knowledge hiding on subordinate knowledge hiding.

Practical implications
Because alexithymia, social inhibition and negative affectivity may predispose employees to knowledge hiding, managers should identify these personality traits among job applicants and hired employees to make appropriate employment decisions. Moreover, managers should be aware that hiding knowledge by a supervisor may be imitated by subordinates.

Originality/value
Based on conservation of resources theory, this study investigates previously unexplored relationships among alexithymia, social inhibition, affectivity and knowledge hiding.
Leadership development through experimentation: a theoretical framework and empirical test
Authors: Birkinshaw Julian , Gudka Maya 
Published: April 2022

Purpose Many theories have been proposed to understand and improve the process of leadership development. One useful way to structure the literature is around three complementary perspectives, briefly summarized as the “knowing, doing and being” dimensions of leadership. While the complementarities between these perspectives have been discussed, the mechanisms by which they are linked are less clear. The purpose of this paper is to examine the role of experimentation as one such mechanism.Design/methodology/approach Building on interviews and prior literature, the authors argue that experimentation consists of two processes: task-prototyping focused on the work overseen by the leader and self-prototyping focused on how the leader relates to others. This study proposes a theoretical framework linking experimentation to action-taking (e.g. being entrepreneurial and taking on challenging assignments), which in turn links to leader effectiveness. The authors test the hypotheses on two groups of leaders (481 business school alumni and 310 financial services leaders).Findings The authors find evidence that both forms of experimentation provide significant explanatory power in understanding why some individuals engage in higher levels of action-taking than others. Additionally, their study confirms the central role of action-taking in leadership development.Originality/value Conceptually, this study distinguishes two dimensions of experimentation and their connection to action-taking, knowledge development and identity development. Empirically, the authors show that these two experimentation activities were significant predictors of action-taking, even after controlling for all other factors, and that action-taking (along with self-prototyping) was an important predictor of leader effectiveness. The results offer a practical framework for leadership and development professionals to use in designing and evaluating leadership development activities.
Better together: involving consumers in the ideation, creation and dissemination of transformative value
Authors: Bilstein Nicola , Verlegh Peeter W.J. , Klostermann Jan , Akpinar Ezgi 
Published: April 2022

PurposeConsumers play a central role in the creation of transformative value, enhancing the well-being of people and the planet. With this article, the authors synthesize service and communication scholars' views to conceptually discuss opportunities and challenges on how to involve consumers in the ideation, creation and dissemination of transformative value. In doing so, the authors identify avenues for future research.Design/methodology/approachThis research relies on a review of service and communication literature, connecting their insights to real world examples.FindingsConsumers are involved in the ideation, creation and dissemination of transformative value by engaging in customer innovation, customer participation and customer dissemination behaviors. In relation to these types of customer involvement, four overarching research themes emerge in the context of transformative services: (1) the voice of the non-customer, (2) protecting vulnerable customers, (3) consumer literacy and (4) WOM as a double-edged sword.Originality/valueThis research contributes to transformative service research by assessing the opportunities and challenges related to customers' involvement in the ideation, creation and dissemination of transformative value. Additionally, it identifies avenues for the future at the intersection of communication and service research.