bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN PEER SOCIAL SUPPORT DAN ADVERSITY QUOTIENT DENGAN RESILIENSI AKADEMIK MAHASISWA DI MASA PANDEMI
Authors: Gayatri Rika , Isrofin Binti 
Published: March 2022

Penelitian ini membahas mengenai hubungan antara peer social support dan adversity quotient dengan resiliensi akademik pada mahasiswa Universitas Negeri semarang di masa pandemi Covid-19. Tujuan pada penelitian ini ialah memperoleh informasi mengenai tingkat masing-masing variabel serta hubungan antar variabel. Jenis penelitian ini ialah kuantitatif ex post facto dengan desain korelasional. Hasil analisis deskriptif menunjukkan tingkat resiliensi akademik mahasiswa UNNES pada kategori tinggi (M=4,02), tingkat peer social support tinggi (M=3,99), serta tingkat adversity quotient tinggi (M=3,92). Hasil analisis regresi ganda menunjukkan terdapat hubungan positif dan signifikan antara peer social support dengan resiliensi akademik (t=10,636, β=0,445, p=<0,05), terdapat hubungan positif dan signifikan anatara adversity quotient dengan resiliensi akademik (t=10,596, β=0,485,p=<0,05), serta terdapat hubungan positif dan signifikan antara peer social support dan adversity quotient dengan resiliensi akademik (R=0,880, R2 =0,774, F=586,225, p=<0,05) yangmana secara simultan dapat memprediksi resiliensi akademik sebesar 77,4%. Berlandaskan hasil penelitian, diharapkan dapat diimplikasikan bagi pengembangan program bimbingan dan konseling pada pusat karir dan bimbingan dan konseling universitas.
HUBUNGAN ANTARA KEPRIBADIAN TANGGUH DAN DUKUNGAN SOSIAL DENGAN STRES AKADEMIK SISWA SMAN SE-KABUPATEN PASER
Authors: Rahayu Sasanti Puji , Isrofin Binti 
Published: March 2022

Penelitian ini membahas mengenai hubungan antara kepribadian tangguh dan dukungan sosial terhadap stres akademik SMAN Se-Kabupaten Paser.Tujuan pada penelitian ini ialah memperoleh informasi mengenai tingkat masing-masing variabel serta hubungan antar variabel. Jenis penelitian ini ialah kuantitatif ex post facto dengan desain korelasional. Hasil analisis deskriptif menunjukkan tingkat stres akademik sedang (M=2,75), tingkat kepribadian tangguh sedang (M=2,70), serta tingkat dukungan sosial sedang (M=2,78). Hasil analisis regresi ganda menunjukkan terdapat hubungan negatif dan signifikan antara kepribadian tangguh dengan stres akademik (t=-2,791, β=-0,116, p=<0,01), terdapat hubungan negatif dan signifikan antara stres akademik (t=,-0,112, β=-0,006,p=<0,01), serta terdapat hubungan dan signifikan antara kepribadian tangguh dan dukungan sosial terhadap stres akademik (R=0,181, R2 =0,033, F=4,268, p=<0,01) yang mana secara simultan dapat memprediksi stres akademik sebesar 3,3%. Berlandaskan hasil penelitian, diharapkan dapat diimplikasikan bagi Guru BK di sekolah
Importanța nivelurilor proteinei C reactive serice în COVID-19 | [The importance of serum C-reactive protein levels in COVID-19]
Authors: Costinaș Carmen-Sarah 
Published: March 2022

Introduction: COVID-19 is an infectious disease caused by the novel coronavirus SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). World Health Organization declares COVID-19 a global pandemic on the 11th of March 2020. Objective: Considering that there is no successful treatment to cure the disease, it is highly important to find a way to predict the severity of the infection in order to improve healthcare strategies. Some serum biomarkers are linked to the infection and evolution of COVID-19. Discussions and conclusions: Among other biomarkers, C Reactive Protein (CRP) is useful in anticipating the poor outcome in COVID patients. For every 1 unit increase in CRP levels, the risk of developing a severe form of COVID-19 increases by 5%. Besides its predictive role, CRP guides the doctors in taking the decision of administrating dexamethasone to decrease the systemic inflammation induced by SARS-CoV-2.
Rezumat
Introducere: COVID-19 este o boală infecțioasă cauzată de noul coronavirus SARS-CoV-2 (coronavirus producător de sindrom respirator acut sever). Organizația Mondială a Sănătății declară pandemie de COVID-19 pe 11 Martie 2020. Obiectiv: Având în vedere că nu exită un tratament curativ pentru această boală, este important să se descopere o modalitate de a prezice evoluția cu potențial sever, cu scopul de a îmbunătăți strategiile salvatoare de viață. Anumiți markeri serici se corelează cu infectarea și evoluția COVID-19. Discuții și concluzii: Printre alți biomarkeri serici, se distinge proteina C reactivă (PCR) care ajută la anticiparea evoluției nefavorabile a pacienților COVID. Pentru fiecare unitate PCR crescută, riscul de a dezvolta o formă severă crește cu 5%. Pe lângă rolul său predictiv, PCR ajută medicii să selecționeze cazurile ce ar beneficia de tratamentul cu dexametazonă, menit să combată inflamația sistemică indusă de SARS-CoV-2.
Office-based management of Bartholin cysts and abscesses: a comparison of three surgical methods
Authors: ERDOĞAN Gökçen , ŞİMŞİR Coşkun 
Published: March 2022

Aim: In the present study, we aimed to compare the effectiveness of incision + drainage alone, marsupialization, and incision + drainage followed by silver nitrate application for the office management of Bartholin cysts/abscesses.
Material and Method: A total of 128 women who presented to our clinic, diagnosed with Bartholin cysts/abscesses and underwent Bartholin gland sparing office-based surgery were included in this retrospective study. Patients’ demographic data, laterality and size of the cyst, surgical method performed, operational time, presence of recurrence, and treatment method of recurrent cysts/abscesses were recorded. Patients were divided into three group according to the operation they have undergone as incision + drainage alone, incision + drainage followed by silver nitrate, marsupialization.
Results: The mean cyst diameter was found as 3.00±1.05 cm. Eighteen (14.1%) patients developed recurrence. Of all patients, 37.5% underwent incision + drainage alone, 8.6% incision + drainage followed by silver nitrate application and 62.5% marsupialization. The mean operational time was significantly longer in the marsupialization group compared to incision + drainage alone and incision + drainage followed by silver nitrate groups (both, p
Tranexamic acid in knee arthroplasty: the effect of preoperative intravenous administration of together with postoperative intravenous maintenance and periarticular administration on bleeding, transfusion, and hospitalization time – a retrospective cohort study
Authors: BASILGAN Seçkin , POLAT Abdulkadir , BUYUKKUSCU Mehmet Ozbey , DİNÇEL Yaşar Mahsut , YAĞMURLU Fırat 
Published: March 2022

Objective: To compare patients who received preoperative intravenous (IV) plus postoperative maintenance IV tranexamic acid (TXA) therapy and perioperative periarticular TXA to those who did not receive TXA during total knee arthroplasty (TKA) in terms of blood loss, transfusion requirements, and length of hospital stay.
Material and Method: Data from 194 patients who underwent TKA between 2016 and 2019 were reviewed. A total of 106 patients were included. Twenty-one patients were male, and 95 were female. The patients were divided into three groups: Group 1 (n=37) that did not receive perioperative TXA, Group 2 (n=35) that received preoperative IV and postoperative maintenance TXA therapy, and Group 3 (n=34) that received preoperative IV and perioperative periarticular TXA. The groups were similar regarding demographic data. Statistical comparisons between the groups were made concerning the decrease in hemoglobin levels on postoperative days 1 and 3, the need for transfusion, and the length of hospital stay.
Results: The mean decrease in hemoglobin on the postoperative first and third days were 1.69(±1.13) and 2.94(±1.14)g/dl, in Group 1, 1.41(±0.99) and 2.44(±1.28)g/dl, in Group 2, and 1.24(±0.83) and 2.21(±0.84)g/dl in Group 3 respectively. The statistical comparison of the hemoglobin decrease revealed a significant difference between Groups 1 and 3 on the postoperative first day(p
Is there any difference between shaving versus clipping versus depilatory gel of hair removal for skin preparation before surgery in respect of wound infection?
Authors: TURHAN Veysel Barış , TOPCU Ramazan , YILDIZ Alp 
Published: March 2022

Aim: Postoperative wound infection is still the most developing complication after surgery and globally responsible for almost %25 hospitalizations requiring complications after surgery. Several significant parameters to minimize Surgical Site Infection (SSI) evaluated and published in many articles, reviews, and guidelines. We aim to investigate the SSI outcomes of 3 different hair removal procedures before surgery, including skin preparation, in this original research article.
Material and Method: 314 patients enrolled in this study were males aged 18 and 65, admitted to the outpatient clinic with unilateral inguinal hernia, and were eligible for Lichtenstein tension-free open hernia repair using mesh.
Results: Wound infection has occurred in 6 patients from Group-1 (4.83%), 8 patients on Group-2 (7.92%), 4 patients on Group-3 (4.49%). There are no statistically significant between Group1 and Group-3 (p>0.05) when the wound infection rates of Group-2 statistically significantly higher than Group-1 and Group-3 (p
Evaluation of the efficiency of treatment in girls with central precocious puberty/rapidly progressive puberty via ultrasonography
Authors: FİDAN Nurdan , KENDİRCİ Havva Nur Peltek 
Published: March 2022

Introduction: Central precocious puberty (CPP) is defined as the development of secondary sexual characteristics in girls before the age of 8 years due to the activation of the hypothalamus-pituitary-gonadal (HPG) axis, and long-acting GnRH analogues (GnRHa) are used in its standard treatment. The gold standard method for evaluating the efficiency of treatment is to demonstrate the suppression of the LH response with the GnRH stimulation test. Pelvic ultrasonography (US) is an easily accessible, safe, free of ionizing radiation and non-invasive imaging method, which is used for the evaluation of internal genital organs, monitoring of sexual development, and excluding ovarian mass. This study aimed to evaluate the effect of GnRHa treatment on internal genital organs and to determine the role of pelvic ultrasonography in treatment follow-up.
Material and Method: Between January 2017 and May 2021, 50 girls who were started on GnRHa treatment due to the diagnosis of CPP or rapidly progressing puberty were followed up, and who underwent pelvic US imaging at the beginning of treatment and in the 1st year of treatment were included in the study. The clinical and sonographic findings were compared before and after the treatment.
Results: Of the 50 patients in the study, 52% (n=26) were being followed up with CPP, and 48% (n=24) with rapidly progressive puberty. In the first year of GnRHa treatment, while the suppression of the HPG axis was detected in 82% (n=41) of the cases with the GnRHa test, there was no suppression in 18% (n=9). A decrease in ovarian volume was observed in 73.2% (n=30) of 41 patients with suppression of the HPG axis, a decrease in uterine volume in 65.9% (n=27), and a decrease in uterine anterior-posterior size in 61% (n=25). While endometrial thickness could be measured in 64% (n=32) of the cases before treatment, measurable endometrial thickness was detected in only 6% (n=3) of the cases in the 1st year of treatment.
Conclusion: We detected in this study that GnRHa treatment in girls with a diagnosis of CPP/rapid puberty caused a significant regression in ovarian and uterus dimensions and endometrial echo selectability. Our results, in line with the literature, support that pelvic ultrasonography is an appropriate modality for monitoring the suppression of the HPG axis during CPP treatment and may reduce the need for repeated GnRH stimulation tests.
Comparison of prone position effectiveness with percentage of injured lung area in awake non - intubated COVID-19 patients
Authors: GÜRSOY Canan , ORAL TAPAN Özge , DOĞAN Emrah , TOGAN Turhan , DEMİRBİLEK Semra 
Published: March 2022

Aim: Prone position plays a key role in the treatment of both non-intubated and intubated patients because COVID-19 associated respiratory failure is gas exchange abnormalities based on shunt and dead-space ventilation. In this study, we aimed to compare the effect of prone position applied in awake non-intubated COVID-19 patients with percentage of injured lung area.
Material and Method: 65 patients with awake, non-intubated were included in this prospective, single-center study. Percentage of injured lung area was calculated using chest computer tomography taken during diagnosis of patients. The prone position cycle was applied as 6 hours prone, 4-6 hours supine position.
Results: The mean of percentage of injured lung area was 25.16±13.81. When percentage of injured lung area groups were compared with the 0th, 6th, 24th and 48th hour SpO2/FIO2 ratio and respiratory frequency; while the SpO2/FIO2 ratio increased in all hours with prone position in the 0-10% and 10-30% groups, a decrease was observed in the SpO2/FIO2 ratio over time in the ≥ 30% group.
Conclusions: The prone position is a safe and effective application that causes improvement in SpO2/FIO2 ratio and RR in awake non-intubated COVID-19 patients with less damage to the lung. However, it should be kept in mind that as the damage to the lung increases, the expected recovery might not be possible.
Effectiveness of hydrodistention procedure under local anesthesia in the treatment of bladder pain syndrome/interstitial cystitis
Authors: SARIKAYA Kubilay , ŞENOCAK Çağri , İBİŞ Muhammed Arif , SADİOĞLU Fahri Erkan , ÇİFTÇİ Mehmet , BOZKURT Ömer Faruk 
Published: March 2022

Objective: We aimed to indicate the effectiveness of local anesthesia in the treatment of hydrodistention in women with Bladder Pain Syndrome/interstitial Cystitis (BPS/IC) in our study.
Material and Method: The data of a total of 77 female patients who underwent hydrodistention treatment for BPS/IC in our clinic between January 2015 and July 2021 were analyzed retrospectively. The patients were divided into two groups as local anesthesia (LA, n=41) and spinal anesthesia (SA, n=36) groups according to the type of anesthesia applied. The groups were compared by determining the preoperative and postoperative O'Leary symptom index (SI) and problem index (PI), minimum voiding volume (MinVV), maximum voiding volume (MaxVV), average voiding volume (AvgVV) and daily frequency.
Results: The mean age of the patients was 48.97±11.09 years in the LA group and 45.19±14.35 years in the SA group (p=0.197). There was no significant difference between the groups in terms of the preoperative European Society for the Study of Interstitial Cystitis (ESSIC) group (p=0.999). During the postoperative period, a median (IQR) improvement of 11.0 (2.0) points was observed in the SI of the LA group, while a median improvement of 11.0 (2.0) points were observed in the SA group (p=0.437). The median improvement in PI score was 8.4 (4.0) points in the SA group, while it was 7.0 (3.0) points in the LA group (p=0.415). There was no significant difference between the groups in terms of improvements in minVV, maxVV, avgVV and daily frequency (p=0.480, p=0.460, p=0.614 and p=0.910, respectively).
Conclusion: Hydrodistention treatment in women with BPS/IC can be performed safely and with high success rate under local anesthesia and it is well tolerated by the patients. Local anesthesia offers a minimally invasive treatment option as well as the advantage of avoiding possible complications of spinal, epidural or general anesthesia.
Evaluation of the relationship of hemogram parameters with prognosis in older adults with acute abdominal pathologies
Authors: AKÇA Hatice Şeyma , ALGIN Abdullah , ÖZDEMİR Serdar , YILMAZ Burcu , ALTUNOK İbrahim 
Published: March 2022

Aim: We aimed to investigate the effects of hemogram parameters on the short-term mortality of older adults with acute abdominal pathologies. Secondly, it was aimed to investigate the effect of hemogram parameters on mortality in operated and non-operated patients.
Material and Method: This retrospective observational study was conducted in an emergency medicine clinic between June 1, 2019, and June 1, 2020. Data on patients over 65 years of age who presented to the emergency department with acute abdominal pathologies were analyzed. Hemogram parameters, as in our patient group over 65 years old, who presented with all acute abdomen pathologies; It was examined in terms of its relationship with prognosis in our operated and non-operated patient group. Statistical analysis was performed using SPSS v. 26.0.
Results: The study included a total of 744 patients, of whom 391(52.6%) were women. Mortality was seen in 114(15.32%) patients, and 83(11.2%) patients underwent surgery. AUC and cut off values are for leukocytes count 0.590 and 10.83 for neutrophils count 0.596 and 9.64 for neutrophil-lymphocyte ratio 0.606 and 8.24 to predict mortality (p=0.002, p=0.001, and p>0.001, respectively
Conclusion: In this study, among the hemogram parameters; leukocytes, neutrophils and neutrophil-lymphocyte ratio were determined to have a statistically significant ability to predict mortality in older adults both operaple and non operabl groups groups presenting with acute abdominal pathologies, but their accuracy rates were low.
Is the systemic immune-inflammation index a predictive marker of carotid artery stenosis?
Authors: KARACAN GÖLEN Meltem , YILMAZ OKUYAN Dilek 
Published: March 2022

Introduction: The relationship between inflammation and atherosclerosis and ischemic stroke was shown in studies, and we aimed to evaluate the relationship between the systemic immune-inflammation (SII) index and carotid artery stenosis (CAS) in our study.
Material and Method: Forty patients with CAS with acute cerebrovascular disease and sixty three patients without CAS with acute cerebrovascular disease were included in the study. Demographic characteristics, neutrophil/lymphocyte ratio ( NLR), and the SII indexes of the patients were compared between the groups with and without CAS.
Results: There was a statistically significant difference between the groups in terms of NLR and SII index values (p
Morphological and immunohistochemical evaluation of interface lesions between chronic lymphocytic thyroiditis and papillary thyroid cancers
Authors: CELEPLİ Pınar , BİGAT İrem , CELEPLİ Salih , HÜCÜMENOĞLU Sema 
Published: March 2022

Objective: To evaluate the expression of papillary thyroid carcinoma-associated tumor markers in reactive and dysplastic changes showing papillary thyroid carcinoma-like nuclear features in chronic lymphocytic thyroiditis cases.
Material and Method: In this study, we retrospectively analyzed 84 cases diagnosed with chronic lymphocytic thyroiditis based on the analysis of thyroidectomy specimens in our center over the last five years. We classified them as normal, reactive and dysplastic changes and performed an immunohistochemical analysis using HBME-1, Galectin-3, Cytokeratin 19, and Cyclin D1.
Results: The mean age of the patients was 45.5 years, and 68 were female and 16 were male. According to the morphological features, 42.9% of the were classified to have normal morphology, 44.0% reactive atypia, and 13.1% follicular epithelial dysplasia (FED). Of the chronic lymphocytic thyroiditis cases, 42.9% were associated with malignancy, with the most common accompanying malignancy being papillary thyroid cancer (36.9%). Immunohistochemically: for HBME-1, FED (72.7%) was higher (p
Common variable immunodeficiency from the perspective of rheumatology
Authors: YUCE INEL Tuba , CAN Gercek 
Published: March 2022

Aim: Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by impaired B cell differentiation and immunoglobulin production. In addition to increased susceptibility to infection, patients with CVID have an increased tendency to autoimmune disease. Immune dysregulation in these patients may lead to granulomatous disease, malignancy, allergy and autoimmune manifestations. In this study, it was aimed to increase the awareness of rheumatologists about the main signs and symptoms of CVID.
Material and Method: Adult patients followed in the rheumatology department between January 2015 and September 2021 were included in the study. Demographic and clinical characteristics (infections, pulmonary and extrapulmonary granulomatous involvement, autoimmune manifestations), laboratory and imaging findings and treatments of the patients were analyzed.
Results: Ten adult patients with CVID were included in the study. At least one autoimmune manifestation was observed in 80% of the patients. In the follow-up period, 40% of the patients developed arthritis. Involvement of lower extremity joints such as knee and ankle was more prominent. While all patients were given 0.8 g/kg/3 weeks of intravenous immunoglobulin, 80% required immunosuppressive therapy for autoimmune manifestations.
Conclusion: Autoimmune diseases can be seen in patients with CVID, and sometimes this may be the first presentation of CVID. Heterogeneous clinical findings of the disease may lead to delay in diagnosis. Clinicians should be more careful about the different manifestations of CVID to avoid delay in diagnosis.
Myeloperoxidase deficiency: a single center experience
Authors: ARMAN BİLİR Özlem , ÖZBEK Namık Yaşar 
Published: March 2022

Aim: Myeloperoxidase (MPO) deficiency is the most common inherited defect of phagocytes. In this article, we aimed to reveal clinical characteristics of our patients with primary MPO deficiency.
Material and Method: In our study, patients aged 0-18 years, who were consulted to Ankara City Hospital Pediatric Hematology Department between 1 October 2019 and 1 December 2021 due to neutropenia, were retrospectively examined. If a patient had neutropenia in the complete blood count and inconsistently normal neutrophil count in the peripheral blood smear formula it was accepted as pseudoneutropenia. Patients with pseuduneutropenia were included in the study.
Results: Fifteen patients diagnosed with MPO deficiency were analyzed in the study. Nine of the patients were female, 6 were male, median age of the patients was 7 (0 – 17.5) years. The mean white blood cell (WBC) count of the patients was reported as 8219±2879/mm3, and the mean neutrophil count and percentage in the complete blood count printout was 33.30±15.88/mm3 and 0,74%±0, 94% respectively. The mean neutrophil count and percentage counted in the peripheral blood smear were 5186±1710 and 63.8%±10.59%, respectively. The mean LUC value on the complete blood count printout was 54.35%±19.47% (Normal range, 0-4%). In the flow cytometry evaluation of peripheral blood samples of the patients, it was observed that neutrophils were stained with CD33, CD13, CD16, CD11b monoclonal antibodies but not with MPO.
Conclusion: Peripheral smear evaluation is important when investigating the etiology of neutropenia. Many hematology analyzers using the MPO staining technique are indicative of MPO deficiency by identifying large unstained cells that do not stain with MPO. In patients who present with recurrent infections and MPO deficiency, other reasons that may predispose to infections should be investigated.