bluuebunny/crossref_metadata_2025_split huggingface dataset:
Palliative Care Programs in Children’s Hospitals
Authors: Weaver Meaghann S. , Shostrom Valerie K. , Kaye Erica C. , Keegan Amy , Lindley Lisa C. 
Published: September 2022

BACKGROUNG AND OBJECTIVES
This study determined the prevalence of PPC programs in the United States and compared the environment of children’s hospitals with and without PPC programs.

METHODS
Analyses of the multicenter Children’s Hospital Association Annual Benchmark Report 2020 survey for prevalence of PPC programs and association with operational, missional, educational, and financial domains.

RESULTS
Two hundred thirty-one hospitals received Annual Benchmark Report survey requests with 148 submitted (64% response rate) inclusive of 50 states. One hundred nineteen (80%) reported having a PPC program and 29 (20%) reported not having a PPC program. Free-standing children’s hospitals (n = 42 of 148, 28%) were more likely to report the presence of PPC (P = .004). For settings with PPC programs, the median number of staffed beds was 185 (25th quartile 119, 75th quartile 303) compared with 49 median number of staffed beds for those without PPC (25th quartile 30, 75th quartile 81). Facilities with higher ratio of trauma, intensive care, or acuity level were more likely to offer PPC. Although palliative care was associated with hospice (P &lt;.001) and respite (P = .0098), over half of facilities reported not having access to hospice for children (n = 82 of 148, 55%) and 79% reported not having access to respite care (n = 117 of 148).

CONCLUSIONS
PPC, hospice, and respite services remain unrealized for many children and families in the United States. Programmatic focus and advocacy efforts must emphasize creation and sustainability of quality PPC programs in smaller, lower resourced hospitals.
Association of pili with widespread multidrug-resistant genetic lineages of non-invasive pediatric Streptococcus pneumoniae isolates
Authors: Alexandrova Alexandra Sashova , Pencheva Daniela Rosenova , Setchanova Lena Petrova , Gergova Raina Tsvetanova 
Published: September 2022

Abstract
The study aimed to evaluate the presence of pili in non-invasive pediatric pneumococcal isolates and to elucidate possible links with genetic lineages, serotypes, and antimicrobial resistance. We examined 147 Streptococcus pneumoniae isolates from children with respiratory tract infections and acute otitis media. Serotyping was performed by latex agglutination and capsule swelling reaction. Serogroup 6 was subjected to PCR-serotyping. Minimum inhibitory concentrations were determined according to EUCAST breakpoints. PCRs for rlrA and pitB genes were performed to detect a presence of type 1 and type 2 pili. MLST was conducted to define the clonal structure of the piliated strains. Almost all children (96.5%) were vaccinated with the pneumococcal conjugate vaccine PCV10. We detected 76.8% non-PCV10 – serotypes (NVTs) and 14.3% PCV10 serotypes. The predominant serotypes were NVTs: 19A (14.3%), 6C (12.2%), 3 (9.5%), 15A (7.5%) and 6A (6.8%). PI-1 was detected among 10.9% non-PCV10 serotypes 6A, 6C, and 19A and 6.1% PCV10 serotypes 19F and 23F. Type 2 pili were not found in the studied population. High levels of antimicrobial nonsusceptibility to erythromycin (58.5%), oral penicillin (55.8%), clindamycin (46.9%), trimethoprim-sulfamethoxazole (45.6%), tetracycline (39.5%) and ceftriaxone (16.3%) were revealed. The multidrug-resistant strains (MDR) were 55.1%. MLST represented 18 STs and three CCs among the piliated pneumococci: CC386, CC320, and CC81. More than half of the piliated strains (56.0%) belonged to successfully circulating international clones. PI-1 was associated mainly with MDR 6A, 6C, 19A, 19F, and 23F isolates from the widespread CC386, CC320, and CC81.
The results of an observational study of the effectiveness of complex oral therapy of Peyronie’s disease in clinical practice
Authors: Kyzlasov P. S. , Gubanov E. S. , Grin E. A. , Nashivochnikova N. A. , Krasnyak S. S. 
Published: September 2022

Background. Peyronie’s disease is a disease characterized by chronic inflammation of the protein membrane of the fibrous tissue of the penis. Oral pharmacotherapy allows a long-term effect on the mechanisms of formation of fibrous plaque.Aim. To evaluate the degree of change in complaints against the background of the complex drug Peyroflex® and its effectiveness.Materials and methods. The study was conducted as a prospective observational study. The study included 43 patients with complaints of pain in the penis area during erection or at rest, curvature of the penis, the presence of palpable plaque in the area of the cavernous bodies. Men took Peyroflex® on a regular basis, one capsule (410 mg) 2 times a day for 6 months or until the pain disappeared during erection, but not less than 6 months.Results. The intensity of pain after 3 and 6 months of taking Peyroflex® decreased by 47.8 and 78.3 %, respectively. The severity of penile curvature showed a tendency to decrease by 7.5 % after 3 doses of Peyroflex® and remained stable after 6 months. The plaque area according to the results of ultrasound examination after 3 and 6 months of taking Peyroflex® decreased by 14.7 and 17.2 %, respectively.Conclusion. Peyroflex® can be recommended for use in the active phase of Peyronie’s disease both in monotherapy and in combination with other methods of treatment (extracorporeal shock wave therapy, physiotherapy, etc.).
Investigation of the effect of COVID-19 infection on sperm DNA fragmentation
Authors: Sorokina T. M. , Bragina E. E. , Sorokina E. A. , Sedova A. O. , Shtaut M. I. , Kurilo L. F. , Chernykh V. B. 
Published: September 2022

Aim. To compare sperm parameters and the DNA fragmentation in patients after the COVID-19 infection and in men without a history of infection.Materials and methods. Sperm parameters and DNA fragmentation index were evaluated in 172 patients examined in 2020–2022. Based on the data on COVID-19 infection in the anamnesis, the patient’s cohort was divided into three groups: group 1 (n = 16) and group 2 (n = 65) – patients who had an infectious disease less than 75 days and more than 75 days before the delivery of the ejaculate, respectively, and group 3 (control, n = 91) – men have no coronavirus infection. A standard semen examination was performed according by the WHO guidelines (2010) recommendation. Sperm DNA fragmentation was evaluated by fluorescent labeling of single- and double-strand DNA breaks (TUNEL method).Results. The percentage of spermatozoa with fragmented DNA in group 1 varies from 2 to 48 %, in group 2 – from 0.9 to 39 %, in group 3 (control group) – from 1.3 to 52.9 %. The average number of gametes with DNA breaks in group 1 (11.7 ± 3.3 %) is greater than in group 2 (10.6 ± 0.8 %) and in group 3 (10.7 ± 0.8%), but without a statistically significant differences. The proportions of patients whose DNA fragmentation index exceeds the reference value (≤15 %) in groups 1, 2 and 3 are 18.8; 13.8 and 18.7 %, respectively. The count of progressively motile (PR) and morphologically normal spermatozoa in group 2 is statistically significantly greater than in group 3 (22.5 ± 1.6 % vs 18.0 ± 1.2 % and 5.52 ± 0.47 % vs 4.03 ± 0.31 %, respectively).Conclusion. The content of sperm with fragmented DNA is higher in men examined less than 75 days after COVID-19 disease, than in patients, examined more than 75 days after COVID-19 and in men who have no history of this infection. In group 1 an increased DNA fragmentation index was noted mainly in patients who had suffered from the disease in a moderate form.
Wither Biological Sex? The Gender Takeover: A Position Paper
Authors: Gil Vincent E. 
Published: September 2022

In this position paper, I argue that current ideological and sociocultural shifts in the use and meaning of the term gender have also reconfigured what biological sex means. Both terms have been made isomorphic and synonymic. The paper challenges this novel relationship, exploring its confounded history and unpacking how and why genderqueer theorists intentionally minimize body knowledge to enable expressive individualism. Linguistic, psychological and medical anthropology serve as tools of inquiry in my critique on why gender is now given the greater valence. Data from neurosciences are also used to refute notions of the body being just a “mute facticity,” as such theorists claim. Christian dogmas on sex and gender are also examined, as is the insistence on a binary model of humanity despite intersex births and the factuality of gender dysphoria. Christian incorrections, when perpetuated without ongoing analysis and change, continue what some call epistemic oppressions and hermeneutic injustices, contributing another layer to the problematic of sex and gender ideology as rendered today.
Electrospinning Pullulan to Nanoencapsulate Milk Derived Peptides
Authors: Devaraju R. , Kalla Adarsh M. , Manjunatha H. 
Published: September 2022

Background: Milk proteins are a source of bioactive peptides, which are concealed until released and activated. There is a growing interest and necessity for the use of biologically active milk protein-derived peptides with health-promoting properties in food. Despite several health benefits and functionalities, consumption of bioactive peptides through foods is poor due to their unfavorable flavour or bitter taste, low solubility, poor stability during processing and poor oral bioavailability. Electrospinning is an adaptable process for encapsulation since it does not involve severe temperature and requirement of chemicals for the preparation of encapsulate in the form of nanofibres. Methods: The peptide-loaded electrospun nanofibres are characterized for its surface morphology, encapsulation efficiency, zeta potential and interaction between wall material and peptides. In vitro release studies by dialysis bag technique and antioxidant property by DPPH method. Result: Pullulan at 10, 12 and 14% (w/w) concentrations was used for electrospinning of peptides. Scanning electron micrograph revealed the formation of clean beadfree peptides-loaded pullulan nanofibres at 12 and 14% concentrations. Encapsulation efficiency ranged from 73.00-86.00%. FTIR spectrum and XRD diffractograms showed the nonappearance of interactions between the functional groups of biopolymer pullulan and peptides in the electrospun nanofibres. The peptides from electrospun nanofibres showed sustained release. The antioxidant activity of peptides and those which are in the nanofibres was comparable. The physico-chemical and sensory analysis of milk fortified with peptide loaded nanofibres did not show noticeable difference.
An analysis of compounding in English
Authors: Bérešová Jana 
Published: September 2022

Word formation processes contain compounding as one of the principal processes. In English, forming new words by compounding has been recognised since the language of Anglo-Saxons started to develop. The study aims to search for examples of compounds used in contemporary literary prose, focusing on the conceptualisation of reality. Our study will be based on an analysis of excerpted examples that will be sorted according to common features of the way the language users perceive and capture reality. To create and transfer new meanings effectively, compounding seems to be productive as two or more words are combined and function as a single word. The meaning of the compound is influenced by the meanings of its constituents and the relationship between them. Different combinations of meanings are determined by the way extralinguistic reality is classified by the language community.

Keywords: Compounding, conceptualisation, English, extralinguistic, semantics
Detecting multiple-equilibria and chaos in oil prices and global commodity markets
Authors: Ozkaya Ata 
Published: September 2022

In the past 20 years, commodity markets have been examined under the hypothesis of whether the prices exhibit recurrent patterns or follow the stochastic processes. In this study, we analyze both global energy markets and food markets to detect the presence of multiple equilibria, which may lead to higher spikes in prices and to the occurrence of intermittency. This study focuses on daily prices in Brent petrol and Natural gas markets from 23 May 2017 to 23 May 2022. This time interval covers the period where extraordinary economic and financial policies have been preferred in countries worldwide amid the Covid-19 pandemic crisis. On the other hand, the study investigates global Food index monthly data from 2007M11 to 2022M4. Similarly, the time interval under examination points out the effects of the 2008 global crisis where expansionary monetary policies have been implemented both by the Federal Reserve of the U.S and the European Central Bank. We employed the phase-space reconstruction method for the Crude oil Brent Europe and spot Natural gas prices series, and global Food index data respectively. The main findings of the study demonstrate that commodity markets do not converge to a unique equilibrium level, instead multiple equilibria persist and chaotic behavior occurs. The presence of multiple equilibria leads to an increase in complexity and recurrently causes volatility in commodity markets, which may have spillover effects on other financial markets. Our results suggest that these effects simultaneously increase global inflationary pressures. From the perspective of policy making, it is crucial to establish a strategy to eliminate multiple equilibria and prevent high price spikes. Our findings have important implications for Central bank policies in emerging markets and portfolio and risk management.
Insights into the interaction and discourse in the senior phase natural sciences classroom
Authors: Mudau Awelani V , Netshivhumbe Ndivhuwo 
Published: September 2022

This paper investigated interaction and discourse during teacher classroom practices in the Senior Phase Natural Sciences in some rural schools positioned in the Vhembe District of the Limpopo Province, South Africa. The research method employed was a qualitative interpretative multiple case study design. Two schools were selected, and one Natural Science teacher from each school participated in this study. Classroom observations and interviews were used to collect data from Senior phase Natural Sciences teachers. Natural sciences teachers were interviewed in their schools and observed during classroom practice. The findings of the study show that the type of discourse observed from Natural Sciences teachers was authoritative discourse and the pattern of discourse employed was Initiation Response Evaluation. Teacher questioning was used to develop the lesson and evaluate learner understanding. Teachers used an interactive-authoritative communicative approach during their lesson presentations. The consequences of the approaches the teachers use limit the opportunities for learners to interact amongst themselves and the subject content. It is recommended that besides focusing on subject matter knowledge during continuous development programs, there is a need to focus on interactions and discourse. Furthermore, there is a need to conduct further studies on a large scale so that a suitable intervention program can be designed for in-service teachers.
Penerapan Teknologi Video 360 Derajat Berbasis Virtual Reality Menggunakan Google Cardboard Sebagai Media Alternatif Pengenalan Kampus Institut Teknologi Telkom Purwokerto
Authors: Putra Vico Meylana Eka , Prasetyo Novian Adi , Arifa Amalia Beladinna 
Published: September 2022

Institut Teknologi Telkom Purwokerto (ITTP) merupakan perguruan tinggi swasta yang dikelola oleh Yayasan Pendidikan Telkom dan satu-satunya institut yang berada di Jawa Tengah. Perguruan tinggi yang berfokus pada pengembangan ilmu pengetahuan berbasis teknologi informasi membuat daya tarik tersendiri bagi mahasiswa baru yang melanjutkan studinya pada kampus ini, hal tersebut terbukti dengan bertambahnya jumlah mahasiswa baru yang mendaftar setiap tahunnya. Sebagai civitas akademika tentunya para mahasiswa baru diharapkan mengetahui segala informasi fasilitas sarana dan prasarana didalam lingkungan kampus ITTelkom Purwokerto, terutama seperti ruangan dan fasilitas apa saja yang ada didalam kampus ini. Untuk mengenalkan informasi tersebut kepada mahasiswa baru dapat dilakukan melalui berbagai media yang sudah umum digunakan. Namun untuk menambah pengalaman baru dalam mengenalkan lingkungan kampus tersebut diperlukan teknologi yang dapat memvisualisasikan tempat ruangan tersebut. Oleh karena itu diperlukan suatu media alternatif baru agar dapat memberikan gambaran visualisasi tersebut. Teknologi yang akan diterapkan adalah video 360 derajat dan virtual reality. Dengan memanfaatkan kelebihan dari teknologi ini maka pengguna tidak harus repot bergerak atau pergi ke tempat aslinya. Dengan mengubah keseluruhan bangunan kampus dengan perekaman video 360 derajat menjadi objek virtual, mahasiswa baru dapat mengetahui gambaran ruangan apa saja yang terdapat pada kampus dengan menjalankan aplikasi virtual reality menggunakan perangkat pendukung yaitu kacamata VR. Penulis menggunakan metode Multimedia Development Life Cycle (MDLC) dalam penelitian untuk melakukan perancangan sistem.
Penerapan X Means Clustering Pada UMKM Kab Banyumas Yang Mendukung Mega Shifting Consumer Behavior Akibat Covid-19
Authors: Adhitama Rifki , Burhanuddin Auliya , Febriani Atik 
Published: September 2022

The Covid-19 has become a epidemic that is troubling the public because of the extent and speed of the virus spreading. The Covid-19 has resulted in people being unable to move outside their homes freely so that household consumption has decreased. This condition is similar to the crisis in 1997-1998, where MSMEs and small traders could survive. In Banyumas district, the percentage of MSMEs are in the large, medium, and small groups that can support the habit of Mega Shifting, or businesses that can be done at home so that they can be an economic savior in the covid-19. Clustering is a method of grouping similar objects which are taken from several criteria. X-Means is a grouping method that can be used to effectively calculate the value of K. As for testing the quality of a cluster using the Purity test method, it is said to be "Good" if the results of this Purity are close to 1. The total of MSMEs in the Banyumas district which be grouped is 27,574 MSMEs. The purity based on the results of the cluster is 0.9892 (3 groups), 0.9894 (4 groups), 0.9928 (5 groups), and 0.9677 (6 groups). In 3 groups, the results of grouping are 58 MSMEs belong to large groups, 381 MSMEs belong to medium groups, and 26,602 MSMEs belong to small groups. The recommended MSMEs sectors to face mega shifting are food stalls, culinary, agriculture, snacks, traders, craftsmen, workshops, furniture, constructions, and grocery stores.
Studi Eksperimen Arduino Uno Sebagai Pengendali Kursi Roda Elektrik
Authors: Matarru Andre Amba 
Published: September 2022

Kursi roda digunakan sebagai alat bantu disabilitas. Disabilitas memiliki kemampuan terbatas untuk menggerakkan sendiri kursi rodanya sehingga diperlukan sistem yang memudahkan pergerakan kursi roda. Tujuan penelitian ini adalah merancang sistem pemrograman dari software Arduino IDE dan mengetahui fungsi dari Arduino Uno terhadap kursi roda eletrik . Pemprograman arduino kemudian akan terkoneksi terhadap alat sistem elektrik yang menjadikan Kursi Roda dapat dikendalikan secara praktis. Penelitian ini menggunakan metode eksperimen dengan merancang system kursi elektrik menggunakan system berbasis arduino IDE (Integreted Development Environment). Proses perancangan sistem pemrograman dari software Arduino IDE dengan dirangaikan kepada komponen elektrik pada kursi roda diperoleh berupa program inisialisasi. Pemrograman dari arduino IDE (Integrated Development Environment) menjadi dasar kendali yang dikontrol oleh joystick. Joystick kemudian menjadikan kursi roda daapat bergerak ke segala arah sehingga akan mempermudah pengguna menggerakkan kursi roda.
Analisis Pengaruh Audit Report Lag, Leverage dan Ukuran Perusahaan Terhadap Volatilitas Harga Saham Pada Perusahaan Subsektor Hotel, Restoran dan Pariwisata yang terdaftar di BEI Tahun 2016 – 2020
Authors: Dinda Riski Amalia  
Published: September 2022

Penelitian ini bertujuan untuk menganalisis pengaruh simultan atau parsial variabel audit report lag, leverage, dan ukuran perusahaan terhadap volatilitas harga saham. Survei ini merupakan survei kuantitatif dengan menggunakan data sekunder berupa laporan keuangan perusahaan. Populasi dalam survei ini adalah 35 perusahaan subsektor hotel, restoran, dan pariwisata yang terdaftar di BEI dari tahun 2016 hingga 2020. Metode pengambilan sampel dalam penelitian ini menggunakan metode purposive sampling dengan menggunakan software SPSS25. Sehingga menghasilkan 10 perusahaan. Metode analisis data yang digunakan dalam penelitian ini adalah analisis regresi linier berganda. Analisis data menunjukkan bahwa sementara audit report delay dan ukuran perusahaan berpengaruh negatif signifikan terhadap volatilitas harga saham, variabel leverage tidak berpengaruh signifikan terhadap volatilitas harga saham. Namun, pada saat yang sama, tiga variabel: penundaan laporan audit, leverage, dan ukuran perusahaan memiliki pengaruh yang signifikan terhadap volatilitas harga saham.
Effect of digitalization on unemployment among the elderly population in EAEU countries
Authors: Kadochnikova E. I. , Varlamova Yu. A. , Suyucheva D. T. 
Published: September 2022

Objective: to identify current trends in the labor market under digitalization and the growing risks and global instability in the world and national markets in the EAEU countries.Methods: panel data analysis models, graphical method, least squares method, generalized feasible least squares method.Results: the data of the EAEU countries from 2016 to 2020 show the synchronization of unemployment indicators; a slight increase in the share of unemployed aged 55 and older in all countries except Russia; a decrease in value added produced within the “Information and Communication” type of activity, with the exception of Kazakhstan; during the pandemic, a decrease in the integral indicator of unemployment and the number of unemployed aged 55 and older was found under the influence of the gross value added within the “Information and Communication” type of activity, as well as a decrease in unemployment among elder citizens under the influence of the share of the population using the Internet.Scientific novelty: the current trends of unemployment are reflected, under digitalization and the growing risks and global instability in the world and national markets in the EAEU countries.Practical significance: the main conclusions of the article can be an argument in favor of the competitive advantages of the older population in the labor market under digitalization and uncertainty of economy.