bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of an Online Peer Gatekeeper Training Program for Postsecondary Students on Suicide Prevention in Japan: Protocol for a Randomized Controlled Trial
Authors: Nozawa Kyosuke , Ishii Ayaka , Asaoka Hiroki , Iwanaga Mai , Kumakura Yousuke , Oyabu Yuri , Shinozaki Tomohiro , Imamura Kotaro , Kawakami Norito , Miyamoto Yuki 
Published: April 2022

Background
Postsecondary student suicide is one of Japan’s most severe public health problems. Gatekeeper training (GKT) programs are a generally recommended suicide prevention intervention in Japan. For suicide countermeasures, an online program tailored to students may enhance self-efficacy as a gatekeeper.

Objective
This study aims to describe a research protocol to investigate the effect of a newly developed internet-delivered online peer GKT program to improve postsecondary student self-efficacy as gatekeepers for suicide countermeasures in Japan.

Methods
This study is a 2-arm, parallel, randomized controlled trial with a 1:1 (intervention: waiting list) allocation. Participants (n=320) will be recruited, and those who meet the inclusion criteria will be randomly allocated to the intervention or waiting list control group. An approximately 85-minute, 6-section, internet-based gatekeeper program for postsecondary students has been developed that includes videos to help participants acquire skills as gatekeepers. The intervention group will complete the program within 10 days. The primary outcome, self-efficacy as a gatekeeper, is measured using the Gatekeeper Self-Efficacy Scale at baseline, immediately after taking the program, and 2 months after the survey after completing the program follow-up. To compare the primary outcomes, a t test, where the significance level is 5% (2-sided), will be used to test the intervention effect on an intention-to-treat basis.

Results
The study was at the stage of data collection at the time of submission. We recruited participants for this study during August and September 2021, and data collection will continue until December 2021. The data analysis related to the primary outcome will start in December 2021, and we hope to publish the results in 2022 or 2023.

Conclusions
This is the first study to investigate the effectiveness of an online GKT program for postsecondary students to improve self-efficacy as a gatekeeper using a randomized controlled trial design. The study will explore the potential of an online peer gatekeeper program for postsecondary students that can be disseminated online to a large number of students with minimal cost.

Trial Registration
University Hospital Medical Information Network Clinical Trials Registry UMIN000045325; https://upload.umin.ac.jp/cgi-open-bin/ctr/ctr_view.cgi?recptno=R000051685

International Registered Report Identifier (IRRID)
DERR1-10.2196/34832
ANALISIS TINGKAT DAYA SERAP ANGGARAN BELANJA DAERAH DI KOTA MALANG
Authors: Krisdiyanawati Luluk , Abdullah Muhammad Faisal , Syaifullah Yunan 
Published: April 2022

The purpose of this research is to understand the level of absorptive capacity of regional expenditure budgets in Malang City and to understand the effect of planning variables, procurement of goods and services variables, and human sesource variables on the absorption of regional expenditure budgets in Malang.
This type of research is quantitative research. The population in this research were 20 regional work units in Malang in the form of Agency and Department. The sample of this research is the Regional Financial and Asset Agency, Planning Research and Development Agency, Education and Culture Department, Health Department, and Environment Department in Malang City with respondents occupying positions related to the budget, namely the authority of budgets users, officials making commitments, the technical executive officer of the activity, the official signing the payment order, and the treasurer of the expenditure.
The technical analysis used is multiple linear regression. The results of this research indicated that the human resources variable has a significant positive effect on the absorption of regional budgets. While the planning variable and the procurement of goods and services variable do not significantly influence the absorption capacity of the budget
ANALISIS FAKTOR YANG BERPENGARUH TERHADAP PENDAPATAN PEDAGANG PASAR MANGLI KABUPATEN JEMBER
Authors: Firdaus Nadir Muhammad kahfi , Boedirochminarni Arfida , Wahyudi Muhammad Sri 
Published: April 2022

Many factors influence the income of sellers. This research was aimed to examine the possible factors that affected the amount of income obtained by sellers of Mangli Market. This research was categorized as a descriptive research using quantitative method. This research was conducted in Mangli Market with 163 population of sellers. The samples in this research were 62 respondents taken by using slovin formula technique. Meanwhile the method of data collection were using questionnaires and conducting interview. The variables used included business capital, the duration of business practice, working hours and sellers’ income. The data analysis used was Multiple Linear Regression (OLS) with level of significance of 5%. The result show that the variable of capital significant positive effect of .021 the duration of business practice significant positive effect of .029 ) and working hours significant positive effect of .006 has simultaneously positive effect and significant to income. For individual, capital variable has no effect and significant at the income influence in Mangli Market Mangli Village. Kaliwates sub district, Jember districts
PENGARUH INDUSTRI PENGOLAHAN, TENAGA KERJA, DAN INFLASI TERHADAP PERTUMBUHAN EKONOMI DI JAWA TIMUR TAHUN 1981-2018
Authors: Kusumawardani Maya Wulan , Nuraini Ida 
Published: April 2022

Economic growth is one indicator that is used as a benchmark for the success of the development of an area in East Java whether it has increased or decreased. This study aims to determine how much influence or variables that can influence economic growth in East Java. The analytical tool used in this study is multiple linear regression with time series data interpolated with statistical measurements using Eviews computer by using the classic assumption test and the F t-test analysis. In the results of research that have been carried out it is known that the processing industry has a positive and significant influence on economic growth in East Java with the results of the coefficient 24.73977 and the probability result of 0.0117 as the labor variable which also has a positive and significant effect with the results obtained the regression coefficient is 45.17394 and the probability result is 0.0229 while the inflation variable has a negative and significant effect on economic growth with the results of the regression coefficient of -0.251741 with a probability result of 0.0043.
ANALISIS PENGARUH INFLASI, PDRB, DAN UPAH MINIMUM TERHADAP PENYERAPAN TENAGA KERJA DI JAWA TIMUR
Authors: Warapsari Esthi Bhakti , Hidayat Wahyu , Rochminarni Arfida 
Published: April 2022

The population growth in Indonesia has been increasing steadily, so has the population growth in East Java Province. An increase in population will lead to an increase in the number of workers. The increasing number of workers will become a problem in the world of employment, if the number of workers available is not proportional to the demand for workers who are able to absorb. The results of this study indicate that the results of the study were negative and insignificant to the workforce in East Java Province with a coefficient of -0,000508 and a probability yield of 0.3650, while the GRDP had a positive and significant effect on labor in the East Java Province with a coefficient of 0,026689 and the probability result of 0.0468, and the minimum wage have a positive and significant effect on labor in the Province of East Java with a coefficient result of 0.132291 and a probability result of 0.0000.
PERAN UMKM DALAM MENANGGULANGI KEMISKINAN DI PROVINSI JAWA TIMUR
Authors: Anugerah Fajrin Novi , Nuraini Ida 
Published: April 2022

This study aims to determine the effect of the number of MSMEs and labors of MSMEs to the poverty of East Java during the period 2017-2018. The variables dependent used in this study is the number of poverty in East Java, while the independent variable are number of MSMEs and labor of MSMEs in East Java This study used panel data regression analysis techniques. The selected model in this study by Chow Test and Hausman Test is fixed effect method (FEM). The data used in this research is secondary data. The results of this study indicate a Prob (F-statistic) value of 0.000000. It can be said that simultaneously the variable number of MSMEs and labor of MSMEs have an effect on poverty of East Java. A value Determinasi Coeficient (R2) is 65.65% Panel data regression calculation results in this study indicate that a variable number of MSMEs with t-Statistics amounted to -7.677828 and probability amounted to 0,0000 means variable number of MSMEs have a negative influence and significant impact on poverty, while the variable labor MSMEs with t-Statistics amounted to -0.971239 and probability amounted to 0,3379 means variable number labor of MSMEs has no effect on poverty. Partially, the variable Number of MSMEs and number labor of MSMEs with F-Probability amounted to 0.000000 so that it can be concluded that the two variables have a positive and significant effect on poverty
Determinan Kemiskinan Di Kabupaten Tuban
Authors: Pradita Agus Hari , Riyanto Wahyu Hidayat 
Published: April 2022

The purpose of this research is to know the infulnce Product Domestic Regional Bruto (PDRB) and open unemployment rate on the number of poverty in Tuban Regency the period 2000-2019. The sampel in the study was taken from BPS as much 20 years. The research method used is a quantitative method. The analysis technique used multiple linear regression models with a significant α 0,05 which was supported by the classical assumption test. The research results prove that PDRB variable has a negative and significant on the number of poverty. While the open unemployment rate variabel has a positive and significant on the number of poverty in Tuban Regency period 2000-2019.
PENGARUH PEMBANGUNAN INFRASTRUKTUR JALAN RAYA DAN LISTRIK TERHADAP PDRB DI KOTA MOJOKERTO
Authors: Prasetya Dhimas Ilham , Nuraini Ida , Kusuma Hendra 
Published: April 2022

The purpose of this research is to know the effect of road condition,electricity on PDRB in Mojokerto City. . The method used is a quantitative approach using secondary data obtained from the annual report of BPS of Mojokerto City. The analytical tool used is multiple linear regression. Data was processed through E-views. The results showed that road condition variable and electricity variable have a significant positive effect on PDRB of Mojokerto City. In this study researchers have limitations using only 16 years and using road condition variable and electricity variable as an independent variable so that it can affect theresearch results. The next researcher is expected to beable to develop the number of variables and be able to add observation time.
Pengaruh Harga Minyak Dunia, Inflasi, Konsumsi Rumah Tangga terhadap Pertumbuhan Ekonomi Indonesia
Authors: Almaya Ulin Nuhaella , Rianto Wahyu Hidayat , Hadi Syamsul 
Published: April 2022

This study aims to determine the effect of world oil prices, inflation, and household consumption on economic growth in Indonesia. This research is a type of descriptive research with a quantitative approach using the annual time series in 1988-2018. The analysis technique used in this study is multiple linear regressions with 31 samples. The results showed that both simultaneously and partially, world oil prices and inflation had a significant (negative) effect and household consumption had a significant (positive) effect on economic growth. Based on research results, the government can improve and build oil and gas infrastructure so that it can optimize oil production. This is very useful because it will reduce oil imports and also reduce the inflation rate. The government can also establish monetary policy and fiscal policy to maintain inflation stability. Other policies that can be done are by increasing the amount of goods produced so that the number of goods in circulation increases, setting maximum prices for several types of goods, and also making policies that can control the inflation rate so as to encourage domestic consumption due to price stability, so that consumption expenditure can be increase or can be stable
PENGARUH SEKTOR PARIWISATA TERHADAP PENYERAPAN TENAGA KERJA DI PROVINSI JAWA TIMUR TAHUN 2012-2018
Authors: Indah Fathya Rizki , Nuraini Ida , Syaifullah Yunan 
Published: April 2022

This aims of this reseach to analyze the effect of sector of tourism on absorption of labor in East Java Province in 2012-2018 (Study case: Regency/City in East Java Province). This research used secondary and the data obtained from the Tourism Office of East Java Province, the Office of Manpower and Transmigration of East Java Province and the Central Statistics Agency of East Java Province. The analysis technique in this research is panel data analysis wich is prossed using Random Effect Model (REM) . The dependent variable in this study is labor in the tourism sector in the Regency/City East Java Province in 2012-2018, while independent variables is the number of hotels, the number of restaurants, the number of tourism objects and number of tourists in the Regency / City of East Java Province in 2012. -2018. In this reseach, it is found that the variables number of hotels, the number of restaurants, the number of Tourism objects a positive and significantly. However, for the variable number of tourists a positive but does not effect absorption of labor in the tourism sector in the Regency / City of East Java Province.
Antioxidant, Anti-Inflammatory and Wound Healing Activities of Cochlospermum planchonii Hook. F.
Authors: Fankibe Nakpane , Kantati Yendubé T. , Metowogo Kossi , Kombate Bignoate , Adi Kojdo , Itiblitse Kossitsè , Darré Tchin , Eklu-Gadegbeku Kwashie , Aklikokou Kodjo A. 
Published: April 2022

Objective: The medicinal plant Cochlospermum planchonii Hook.f. is used in the management of various ailments in Togolese pharmacopoeia. In this study, we aimed to evaluate the antioxidant and anti-inflammatory activities of roots and leaves of C. planchonii, and burn wound healing activity of its leaf hydroethanolic extracts in rodents.
Materials and Methods: Antioxidant activities were assessed using Phosphomolybdenum assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) test and the reducing power assay. Visceral pain model, formaldehyde-induced paw edema and vascular permeability test were performed to evaluate anti-inflammatory activities in vivo. Burns were induced in rats by applying on the skin of the dorsal region an aluminum plaque preheated to 100°C for 10 seconds. Animals were treated topically with empty Carbopol gel, C. planchonii leaves extract 2.5 and 5 % in Carbopol gel, and Brulex® (Zinc oxide 15 % cream).
Results: C. planchonii extracts exhibited good antioxidant capacities close to standard compound, ascorbic acid. Leaves and root hydroethanolic extracts (1000 mg/kg), compared to control animals, significantly reduced the number of writhings (P<0.001) and the volume of paw edema (P<0.001). Similarly, both roots and leaf extracts at 1000 mg/kg have significantly inhibited vascular permeability by approximately 50% compared to the control group. C. planchonii leaves hydroethanolic extract 2.5 and 5 % in Carbopol enhanced wound healing via significantly increased contraction rates (78.63 ± 1.57 and 79.68 ± 1.48 respectively on day 12, P<0.001), confirmed by histological observations.
Conclusion: C. planchonii can promote burn healing due to anti-inflammatory, antioxidant and antimicrobial properties of the plant.
Keywords: Cochlospermum planchonii, inflammatory, antioxidant, edema, burn wound
Phytochemical, toxicity and antihyperglycaemic effects of Zea mays Linn leaves’ extracts
Authors: KOTIN Lucrèce Mahoutin , ASSOGBA Fidèle Mahoudo , AKAKPO Huguette Baï , AHOUNOU AIKPE Judith Fifamin , GODONOU Jean-Benoît , DANSOU Pierre Houndjovi , GBENOU Joachim Djimon 
Published: April 2022

In the Republic of Benin, several plants, including Zea mays Linn (Z. mays) are used for the treatment of diabetes without any scientific studies showing their effectiveness. The objective of this study is to investigate the effects of Z. mays leaves’ extracts on hyperglycaemic rabbits using the Oral Glucose Tolerance Test (OGTT), 2 g/kg of (D) + glucose and on hepatic glucose liberation. Phytochemical screening revealed that the plant leaves contain alkaloids, tannins, mucilage flavonoids, anthocyanin, leuco-anthocyanin, coumarins, heteroside, flavonoid, triterpenoids, steroids, reducing compounds, saponins, oses and holosides. Cytotoxity tests showed that the aqueous and ethanolic extracts were free of toxicity. The extracts have shown anti-hyperglycaemic activities dependent on specific dosage and timing. The effective dose is 500 mg/kg for the aqueous extract and for the ethanolic extract. The extracts are effective as compared with glibenclamide (reference product). Moreover, the ex vivo test conducted on the liver revealed that Z. mays aqueous extract inhibits the hepatic glucose liberation and 500 mg/kg is the most effective dose.
The results of this study justify the traditional usage of the plant leaves under consideration in the treatment of diabetes.
Key words: Zea mays extracts, phytochemical, hyperglycaemia, hepatic glucose, toxicity, Benin.
The Effect of Foot Exercise on Daily Activities and Blood Sugar Levels of Elderly in South Bangka, Indonesia
Authors: Nurhayati Nurhayati 
Published: April 2022

Background: The elderly are a group of people who are at risk of developing diabetes mellitus. Foot exercise is appropriate for elderly people with diabetes to prevent injuries and help improve blood circulation in their feet and also could control blood sugar level. Objective: This study time to determine the effect of foot exercise on daily activities and blood sugar levels among elderly in Tanjung Ketapang Village, Toboali District, South Bangka Regency. Methods: The research employed a quasi-experimental one-group pretest-posttest design. Data were collected using two-part questionnaires: (1) contains the characteristics of the respondents, including age, gender, education, occupation, and (2) contains questions about Activities of Daily Lives and Blood Glucose Level. Data were analyzed using the Statistical Product and Service Solution program with the Independent t-test and then presented in univariate and bivariate analysis. Results: The study found the correlation between Activities of Daily Lives and Blood Glucose Level on foot exercise showed that the Blood Glucose Level before the exercise was 2.28, while after the exercise was 1.86. There is an effect of giving foot exercises to the elderly on Activities of Daily Lives and Blood Glucose Level with a significance p-value of 0.013 and 0.000, respectively. Conclusion: Foot exercise can be used as a standard of nursing care in both hospital and community settings to help and promote the program that has been established to reduce Diabetes Mellitus cases in Bangka Belitung Province.
Keywords: Activity of daily lives, blood glucose level, elderly, foot exercise
Educational comics: a change in the attitude of 3M children aged 10-12 years during the covid-19 pandemic
Authors: Pongoh Ariani 
Published: April 2022

Background: Covid-19 is a disease caused by a new type of Coronavirus namely Sars-CoV-2 which is transmitted through close contact and droplets. Symptoms are acute respiratory disorders such as cough, shortness of breath and fever above 38℃. Attitude change is a stimulus or stimulus received by a person, either in the form of a positive or negative response. Educational comics are pictures and writings that make up a story, then packaged into a book. The comic "Kitorang Lawan Corona" is more interesting for the readers. Objective: This study was to analyze the effectiveness of educational comics on changes in 3M attitudes in children aged 10-12 years during the covid-19 pandemic. Methods: The research design used was a quasi-experimental approach with a one group pretest-posttest design. The subjects of this study were students of MI Al-Kautsar Sorong City aged 10-12 years. Measurement of attitude change was carried out before and after giving educational comics using a Likert questionnaire. Analysis of research data using the Wilcoxon test. Results: providing comics education was significantly (p=0.000) effective on changing 3M attitudes in children aged 10-12 years during the covid-19 pandemic. Conclusion: Educational comics are effective in changing 3M attitudes in children aged 10-12 years during the covid-19 pandemic.
Keywords: Attitude change, health protocols, educational comics.
Ficus religiosa: A beneficial medicinal plant
Authors: Kapile Chinmay , Kulkarni Abhijeet , Pardeshi Pooja , Sayed Adnanulhaque , Nehe Akshay 
Published: April 2022

In India, herbs have been the primary means of treatment. The existence of secondary plant metabolites, which are combinations of chemical substances with different amalgams, in one or more sections of medicinal plants confers therapeutic qualities. Ficus religiosa, sometimes known as peepal, belongs to the Moraceae family of plants. The Bo tree, Ficus religiosa, provided shelter to the Buddha as he divined the "Truths." In Ficus religiosa, phenolic components, hydrocarbons, aliphatic alcohols, volatile components, phytosterols, amino acids, furanocoumarins, and a few more types of secondary metabolites have been isolated by phytochemical studies. Both (In vitro and in vivo) pharmacological activities of Ficus religiosa crude extracts and isolated components included anti-inflammatory, analgesic, antimicrobial, antiviral, hypolipidemic, antioxidant, immunomodulatory, antiasthmatic, parasympathetic modulator, estrogenic, anticancer, antiulcer, antianxiety, anthelmintic, endothelial receptor antagonistic, apoptosis inducer, and hypotensive activities.
Keywords: Ficus religiosa, phytoconstituents, pharmacology, toxicity
Innovation and optimization of Rizatriptan Benzoate Oromucosal Tablets by Using Design of Experiment (DoE)
Authors: Sonawane T. D. , Pawar S.P. 
Published: April 2022

The present study deals with the formulation and study of oromucosal tablets of Rizatriptan Benzoate (RB) using different bioahdesive polymer. Nine formulations were prepared by using direct compression method. Hydroxypropyl methyl cellulose (HPMC K4M), Gum acacia and Sodium Alginate were used as buccal mucoadhesive polymer. Ethyl cellulose (EC) used as an impermeable backing layer. FTIR Studies showed no interaction with drug, polymer and excipients. 32 full factorial design was used to optimize the effect of independent variable such as concentration of HPMC K4M (X1) and concentration of Sodium Alginate (X2) on dependent variables such as % drug release (Y1), Mucoadhesive strength (Y2), Swelling Index (Y3). The prepared buccal mucoadhesive tablets were evaluated for weight variation, Hardness, Surface pH and drug content, content uniformity, swelling index, In-vitro drug release study and mucoadhesive strength. In-vitro drug release study showed sustained drug released for 9 hours. The In-vitro release kinetics reveals that formulation DE5 follows Higuchi model for drug release.
Keywords: Buccal Mucoadhesion, HPMC K4M, Sodium alginate, Design of experiments.