bluuebunny/crossref_metadata_2025_split huggingface dataset:
Millimeter-Wave Dual-Band MIMO Antennas for 5G wireless applications
Authors: Sghaier Nizar , Belkadi Anouar , Hassine Islem Ben , Latrach Lassaad , Gharsallah Ali 
Published: November 2022

Abstract
This paper suggests a dual-band 28/38 GHz four element MIMO array based on dual-mode planar monopole antennas for 5G wireless applications. The design structure contains four planar monopole antennas; located at the corners on a 20×20 mm2 size Rogers RO4003 substrate with a dielectric constant of 3.55. The proposed planar monopole antenna has the shape of a crescent. In order to achieve the desired behavior and performance, we engraved two rectangular slots on both sides and also added a notch at the bottom. In addition, we used a partial ground plane to enhance the isolation. Significant isolation ( > − 23 dB) is achieved between antenna elements by employing spatial and polarization diversity techniques. To validate the design concept, a prototype of the four-element MIMO array is designed, fabricated, and measured. The experimental results show that the proposed antenna can cover the 27.25–29 GHz and 34.5–41 GHz bands with good isolation and high efficiency. Furthermore, the radiation pattern, the realized gain and the channel capacity are also studied. According to the reached results, the proposed MIMO antenna may be a suitable application-oriented design for 5G MIMO applications at the millimeter-wave range.
European Journal of Medical Research Oxycodone enhances antitumor effect of paclitaxel on human breast cancer SKBR3 cells in vitro
Authors: Liu Fangfang , Yuan Hongmei , Xu Chenyang , Mao Mingjie , Feng Shanwu 
Published: November 2022

Abstract
Background
Increasing evidence has indicated that oxycodone (OXY) can promote or prevent tumor growth and metastasis. However, the influences of OXY combined with paclitaxel (PTX) on the breast cancer cells are unclear. Our study aimed to examine the effects of OXY combined with PTX on the proliferation, apoptosis and migration of human breast cancer SKBR3 cells and the underlying mechanism was explored.
Methods
SKBR3 cells were treated with OXY and/or PTX. The proliferation, apoptosis and invasion of SKBR3 cells were assessed by CCK-8, colony formation assay, flowcytometric, Transwell assay and scratch assays, respectively. In addition, Western blotting was used to detect the expression of related proteins in these cells. The autophagic bodies were observed under a transmission electron microscope.
Results
OXY (0.25, 0.5 and 1 mM) significantly inhibited the viability, colony-forming, migration and invasion of SKBR3 cells as compared to control group. Furthermore, OXY (0.25, 0.5 and 1 mM) markedly induced the apoptosis of SKBR3 cells and the levels of apoptosis-related proteins. In addition, OXY (0.25, 0.5 and 1 mM) and PTX inhibited the proliferation of SKBR3 cells synergistically as compared to PTX group in vitro. Moreover, OXY (0.25, 0.5 and 1 mM) significantly elevated the PTX-induced apoptosis in SKBR3 cells via downregulating the expression of N-cadherin, Becline-1 LC3-Ⅱ, p-Akt and p-mTOR and upregulating E-cadherin expression. Compared with control group, OXY (1 mM) treatment induced autophagy in SKBR3 cells. OXY (1 mM) combined with PTX increased the number and size of autophagy bodies as compared to the PTX group. Moreover, OXY distinguished enhanced antitumor effect of PTX on SKBR3 cells.
Conclusions
Our study indicates that OXY can enhance antitumor effect of PTX on breast cancer in vitro. Hence, the combination of OXY with PTX may serve as a potential strategy for the treatment of breast cancer.
Endophytic bacteria from diseased plant leaves as potential biocontrol agents of cucumber Fusarium wilt
Authors: Tan Yinqing , Du Changxia , Xu Li , Yue Cong , Liu Xingchen , Fan Huaifu 
Published: November 2022

Abstract

Screens for Fusarium wilt antagonistic bacteria have generally focused on screening for antagonistic strains from healthy plants, with few reports of screening for antagonists from leaves of diseased plants. In this study, we used cucumber leaves infected with Fusarium wilt disease for the isolation of antagonists and a total of four endophytes with obvious antagonistic effects were screened. Based on the results of physiological and biochemical experiments and 16S rDNA gene sequencing, four strains were identified as Paenibacillus polymyxa (Y-4, Y-6, Y-14) and Bacillus Zanthoxylum (Y-9), and all antagonistic strains exhibited the ability to produce amylase, pectinase and hydrogen peroxide (H2O2). In pot test, antagonistic bacteria were able to significantly reduce the disease index in cucumber seedlings challenged with the pathogen. Four strains of antagonistic bacteria can alleviate the damage caused by Fusarium oxysporum f. sp. cucumerinum (FOC) invasion by increasing the photosynthetic efficiency, antioxidant capacity and root vigor of cucumber seedlings. In conclusion, the leaves of cucumber diseased strain may also be a potential source for screening novel antagonistic agents against cucumber Fusarium wilt. The screened four strains of antagonists had a certain biocontrol potential against FOC and could play a certain role in environmental-friendly agriculture in the future.
Concept analysis of a distributed thrust system, a novel inductive propulsion method using high energy pulse solenoids in satellite swarms for reusable interorbital freight transport
Authors: Wegener Morgan J. 
Published: November 2022

Abstract
To date only single vehicle thrust designs have been considered for propulsion in space, however there is no limitation preventing multivehicle distributed thrust application designs if a rigid structure can be constructed electromagnetically. By considering the regularity of planetary orbits and distance between orbital paths, a location in space can be targeted for next orbit arrival of a shipping container propelled on an intercepting vector that is a result of inductive propulsion vector combination. This concept is achieved with Nb3Sn high energy pulse solenoids that enable a square pyramidal swarm of satellites to decompose the intercepting orbital transfer vector and propel a 20 tonne steel shipping container towards a destination swarm. This paper is a thought experiment with first pass mechanical analysis that establishes a validity algorithm then concludes that the proposed yoked solenoid design is fit for purpose. Two factors are noted as key variances that must be investigated in further research with numerical modelling tools before the proposed design can be considered fully functional.
Fuzzy Fractional Order Volterra-Fredholm Integro-Differential Equations Using MADM
Authors: KASIMALA NARASIMHA RAO , Chakraverty S. 
Published: November 2022

Abstract
This paper investigates solutions to the fractional integro-differential equation (FIDE) of fuzziness. Here we consider, In the Caputo sense, we look at the fuzzy fractional Volterra-Fredholm integro-differential equation (CFFVFIDE) and use fixed point theory to prove its existence and uniqueness. Moreover, we apply the modified Adomian decomposition method (MADM) to find a solution to the presented problem, and to support our approach, we offer a few examples. We also give visual analysis to see how the solutions behave.
2010 MSC: 26A33, 35R09, 34A07, 45J05.
Periodontitis is associated with combined handgrip strength but not with skeletal muscle mass index in middle-aged U.S. adults from NHANES 2013-2014
Authors: Bunte Kübra , Bahat Gülistan , Cruz-Jentoft Alfonso J , Erdogan Tugba , Zyriax Birgit-Christiane , Beikler Thomas 
Published: November 2022

Abstract
Objectives: Indicators of oral and periodontal diseases have previously been associated with handgrip strength and muscle mass and function in older adults in several populations. However, research in middle-aged adults on the relationship between periodontitis and handgrip strength and skeletal muscle mass – another important indicator of sarcopenia – has been limited. This study investigated the association between periodontitis and sarcopenia indicators in middle-aged adults from a U.S. population.
Materials and Methods: Adults with complete periodontal and whole-body dual x-ray absorptiometry examinations from the 2013–2014 wave of the National Health and Nutrition Examination Survey (NHANES) were analysed using fully adjusted multiple linear regression models for associations between periodontitis diagnosis and severity and skeletal muscle mass index (SMMI) and combined handgrip strength (cHGS).
Results: A subset of 1,912 individuals with a complete periodontal examination and whole-body dual x-ray absorptiometry scan from the NHANES 2013–2014 main cohort (n = 10,683) were included in the analysis. The median age of the participants was 43 years. Overall, 32% of the participants (n = 612) were determined to have periodontitis. Of these, 513 (26.8%) had non-severe (mild or moderate) periodontitis, and 99 (5.2%) had severe periodontitis. Both non-severe and severe periodontitis showed significant associations with cHGS (ß = -2.28, 95% CI -3.57–-0.98 and ß = -2.84, 95% CI -5.37–-0.31, respectively), but not with SMMI.
Conclusion: The findings of the current study indicate that periodontitis and handgrip strength are interrelated. The present study highlights the need of further prospective research to investigate the nature and direction of the relationship between periodontitis and sarcopenia indicators.
Clinical relevance: Future studies can support the screening, prevention and clinical management of sarcopenia and periodontitis, and emphasize the interdisciplinary and complementary approach between the disciplines of geriatric medicine and periodontology.
Converting to an international unit system improves harmonization of results for SARS-CoV-2 quantification: results from multiple external quality assessments
Authors: Buchta Christoph , Kollros Dominik , Jovanovic Jovana , Huf Wolfgang , Delatour Vincent , Puchhammer-Stöckl Elisabeth , Mayerhofer Maximilian , Müller Mathias M. , Shenoy Santosh , Griesmacher Andrea , Aberle Stephan W. , Görzer Irene , Camp Jeremy V. 
Published: November 2022

Abstract

Background: The detection of SARS-CoV-2 vRNA in clinical samples has relied almost exclusively on RT-qPCR as the gold standard test. Published results from various external quality assessments (“ring trials”) worldwide have shown that there is still a large variability in results reported for the same samples. As reference standards of SARS-CoV-2 RNA are available, we tested whether using standard curves to convert Ct values into copies/mL (cp/mL) improved harmonization.
Methods: Nine laboratories using 23 test systems (15 of which were unique) prepared standard dilution curves to convert Ct values of 13 SARS-CoV-2 positive samples to cp/mL (hereafter IU/mL). The samples were provided in three rounds of a virus genome detection external quality assessment (EQA) scheme. We tested the precision and accuracy of results reported in IU/mL, and attempted to identify the sources of variability.
Results: Reporting results as IU/mL improved the precision of the estimated concentrations of all samples compared to reporting Ct values, although some inaccuracy remained. Variance analysis showed that nearly all variability in data was explained by individual test systems within individual laboratories. When controlling for this effect, there was no significant difference between all other factors tested (test systems, EQA rounds, sample material).
Conclusions: Converting results to copies/mL improved precision across laboratory test systems. However, it seems the results are still very specific to test systems within laboratories. Further efforts could be made to improve accuracy and achieve full harmonization across diagnostic laboratories.
CO2 emissions and their changes with H2O emissions, soil moisture, and temperature during the wetting–drying process of the soil mixed with different biochar materials
Authors: Yerli Caner , Cakmakci Talip , Sahin Ustun 
Published: November 2022

Abstract
Biochar is an organic regulator that improves crop yield by regulating soil properties. In addition, this organic regulator is also effective in reducing CO2 emissions from soil. However, considering the management of CO2 emissions together with many factors and the different properties of soil depending on the biochar content, CO2 emissions can vary. Thus, the study investigated the soil moisture and temperature and H2O emissions, which affect the emission, and CO2 emission of biochars with different raw materials applied to the soil in the wetting–drying cycle of the soil. It was determined that biochar applications decreased CO2 emissions, but the share of each biochar material in reduction differed, and CO2 emissions were 82, 51, 20, and 13% lower in straw, hazelnut, apple, and sawdust biochar applications than in soil without biochar, respectively, and significant positive linear relationships of CO2 emissions with soil moisture–temperature and H2O emissions were determined. In addition, in biochar applications, H2O and soil temperature decreased depending on the moisture retention in the soil. In the findings, it can be suggested that straw biochar application to soil is more effective in reducing the severity of increasing global warming, and that soil moisture and temperature should be managed to reduce CO2 emissions.
Effect of Stretching versus Breathing Exercises on Self-reported Pain for Women with Genito-pelvic Pain Penetration Disorder
Authors: El Sayed Sabah Lotfy Mohamed , El Sayed Mohamed Lotfy Mohamed 
Published: November 2022

Background:
Genito-pelvic pain penetration disorder is a common and neglected problem that can affect a woman's quality of life.

Aim of the study:
Evaluate the effect of stretching versus breathing exercises on self-reported pain with penetration during sexual intercourse for women with genito-pelvic pain penetration disorder.

Method:
A quasi-experimental study was conducted on 150 women who were selected using a purposive sampling technique. Data was collected at the gynecology outpatient clinic at Zagazig University Hospital and a private clinic. The evaluation was performed via a structured interview questionnaire and the Marinoff Pain Intensity Scale before the start of the study and at the end of the intervention exercises.

Results:
The two groups showed a significant decrease (P <0.001) in the women self-reported pain intensity upon penetration during sexual intercourse, while there was a more noted decrease in the stretching group compared to the breathing group (P <0.001).

Conclusion:
The study concluded that stretching exercises have a significant role in reducing the self-reported pain intensity of penetration during sexual intercourse and pelvic floor muscle spasm for women with genito-pelvic pain penetration disorder.
IT and the Quality and Efficiency of Mental Health Care in a Time of COVID-19: Case Study of Mental Health Providers in England
Authors: Konteh Frederick Hassan , Mannion Russell , Jacobs Rowena 
Published: November 2022

Background
In England, COVID-19 has significantly affected mental health care and tested the resilience of health care providers. In many areas, the increased use of IT has enabled traditional modes of service delivery to be supported or even replaced by remote forms of provision.

Objective
This study aimed to assess the use and impact of IT, in remote service provision, on the quality and efficiency of mental health care during the pandemic. We drew on sociotechnical systems theory as a conceptual framework to help structure the gathering, analysis, and interpretation of data.

Methods
We conducted a national scoping survey that involved documentary analysis and semistructured interviews with 6 national stakeholders and case studies of 4 purposefully selected mental health providers in England involving interviews with 53 staff members.

Results
Following the outbreak of COVID-19, mental health providers rapidly adjusted their traditional forms of service delivery, switching to digital and telephone consultations for most services. The informants provided nuanced perspectives on the impact on the quality and efficiency of remote service delivery during the pandemic. Notably, it has allowed providers to attend to as many patients as possible in the face of COVID-19 restrictions, to the convenience of both patients and staff. Among its negative effects are concerns about the unsuitability of remote consultation for some people with mental health conditions and the potential to widen the digital divide and exacerbate existing inequalities. Sociotechnical systems theory was found to be a suitable framework for understanding the range of systemic and sociotechnical factors that influence the use of technology in mental health care delivery in times of crisis and normalcy.

Conclusions
Although the use of IT has boosted mental health care delivery during the pandemic, it has had mixed effects on quality and efficiency. In general, patients have benefited from the convenience of remote consultation when face-to-face contact was impossible. In contrast, patient choice was often compromised, and patient experience and outcomes might have been affected for some people with mental health conditions for which remote consultation is less suitable. However, the full impact of IT on the quality and efficiency of mental health care provision along with the systemic and sociotechnical determinants requires more sustained and longitudinal research.
Experiences of Health Care Professionals Working Extra Weekends to Reduce COVID-19–Related Surgical Backlog: Cross-sectional Study
Authors: Matava Clyde , So Jeannette P , Hossain Alomgir , Kelley Simon 
Published: November 2022

Background
During the quiescent periods of the COVID-19 pandemic in 2020, we implemented a weekend-scheduled pediatric surgery program to reduce COVID-19–related backlogs. Over 100 staff members from anesthesiologists to nurses, surgeons, and administrative and supporting personnel signed up to work extra weekends as part of a novel weekend elective pediatric surgery program to reduce COVID-19–related backlog: Operating Room Ramp-Up After COVID-19 Lockdown Ends-Extra Lists (ORRACLE-Xtra).

Objective
In this study, we sought to evaluate staff perceptions and their level of satisfaction and experiences with working extra scheduled weekend elective surgical cases at the end of the 3-month pilot phase of ORRACLE-Xtra and identify key factors for participation.

Methods
Following the pilot of ORRACLE-Xtra, all perioperative staff who worked at least 1 weekend list were invited to complete an online survey that was developed and tested prior to distribution. The survey collected information on the impact of working weekends on well-being, overall satisfaction, and likelihood of and preferences for working future weekend lists. Logistic regression was used to estimate the association of well-being with satisfaction and willingness to work future weekend lists.

Results
A total of 82 out of 118 eligible staff responded to the survey for a response rate of 69%. Staff worked a median of 2 weekend lists (IQR 1-9). Of 82 staff members, 65 (79%) were satisfied or very satisfied with working the extra weekend elective lists, with surgeons and surgical trainees reporting the highest levels of satisfaction. Most respondents (72/82, 88%) would continue working weekend lists. A sense of accomplishment was associated with satisfaction with working on the weekend (odds ratio [OR] 19.97, 95% CI 1.79-222.63; P=.02) and willingness to participate in future weekend lists (OR 17.74, 95% CI 1.50-200.70; P=.02). Many (56/82, 68%) were willing to work weekend lists that included longer, more complex cases, which was associated with a sense of community (OR 0.12, 95% CI 0.02-0.63; P=.01).

Conclusions
Staff participating in the first 3 months of the ORRACLE-Xtra program reported satisfaction with working weekends and a willingness to continue with the program, including doing longer, more complex cases. Institutions planning on implementing COVID-19 surgical backlog work may benefit from gathering key information from their staff.
Una aventura en movimiento: breve historia de los MOOC en la UNAM
Authors: Bucio Jackeline , Melo Flórez Jairo Antonio , Vadillo Guadalupe , Sánchez Mendiola Melchor 
Published: November 2022

Los mooc son experiencias de aprendizaje en línea, abiertas y masivas, que tienen una pluralidad de usos y permiten aprender y explorar una enorme variedad de temas. A partir de la revisión de artículos especializados, análisis de registros internos y entrevistas a tres de las figuras que dieron los primeros pasos en esta aventura de la Universidad Nacional Autónoma de México (unam), presentamos una historia que abarca una década de retos y soluciones incluyendo los desafíos durante la pandemia. Se describen las lecciones aprendidas y los retos a futuro sobre el tema en nuestro medio.
Pengaruh dana perimbangan terhadap ketimpangan pembangunan di Provinsi Jambi
Authors: Oktaviani Wanti , Zulgani Zulgani , Rosmeli Rosmeli 
Published: November 2022

This study aims to analyze: 1) inequality of development in Jambi Province; 3) the effect of general allocation funds (DAU), special allocation funds (DAK), and profit sharing funds (DBH) on inequality in development in Jambi Province. The data used are secondary data sourced from the Central Bureau of Statistics of Jambi Province. The data analysis tool uses Williams Index, and path analysis. The results of the study found that 1) The average Williamson Index value in Jambi Province during the period 2001-2016 is 0.392743, which means that there is a high inequality. 2) Simultaneously DAU, DAK, and DBH have a significant effect on inequality. together DAU, DAK, and DBH are able to explain inequality by 80.00%, while the remaining 20.00% is explained by other variables not found in this study. Partially the variables that significantly influence inequality are DBH while DAU and DAK have no significant effect.
PENGARUH INTENSITAS DAN MOTIF PENGGUNAAN MEDIA INSTAGRAM TERHADAP KEPUASAN MENDAPATKAN INFORMASI FOLLOWERS AKUN @soloinfo
Authors: Ningrum Ratih Kusuma , Prihantoro Edy 
Published: November 2022

Instagram merupakan salah satu media sosial yang banyak diminati masyarakat dengan berbagai kepentingan yang dapat digunakan sebagai salah satu sumber informasi bagi masyarakat. Tujuan dari penelitian ini adalah untuk mengetahui intensitas penggunaan media instagram terhadap kepuasan mendapatkan informasi followers akun @soloinfo. Metode penelitian yang digunakan peneliti adalah Metode penelitian kuantitatif yang berlandaskan pada filsafat positivisme dimana peneliti melakukan teknik pengumpulan datanya menggunakan teknik kuesioner, observasi, dan studi pustaka. Populasi dari penelitian ini adalah 400 followers Aktif @soloinfo. Teori yang digunakan merupakan teori uses and gratifications dengan tingkat informasi, teori ini untuk mendapatkan informasi yang dicari audiens sehingga dapat menggunakan media tersebut yang dapat memuaskan, mendapatkan sosial, dan psikologisnya. Hasil Penelitian menunjukan bahwa intensitas menggunakan media Instagram berpengaruh terhadap kepuasan mendapatkan informasi bagi followers @soloinfo. Semakin sering followers @soloinfo mencari dan mendapatkan informasi dari akun @soloinfo. Sehingga dapat disimpulkan bahwa Intensitas dan Motif Penggunaan Media berpengaruh positif dan signifikan terhadap Kepuasan Mendapatkan Informasi secara simultan.