bluuebunny/crossref_metadata_2025_split huggingface dataset:
ОСОБЕННОСТИ МИГРАЦИИ ТЯЖЕЛЫХ МЕТАЛЛОВ В СИСТЕМЕ «ПРИДОННАЯ ВОДА – ПОРОВАЯ ВОДА – ПОВЕРХНОСТНЫЙ СЛОЙ ДОННЫХ ОТЛОЖЕНИЙ» ПРИБРЕЖНОЙ ЗОНЫ ВОСТОЧНОЙ ЧАСТИ ФИНСКОГО ЗАЛИВА В ВЕСЕННЕ-ЛЕТНИЙ ПЕРИОД
Authors: Шигаева Татьяна Дмитриевна , Кудрявцева Валентина Александровна , Панкратова Надежда Максимовна 
Published: January 2022

Ссылка для цитирования: Кудрявцева В.А., Шигаева Т.Д., Панкратова Н.М. Особенности миграции тяжелых металлов в системе «придонная вода – поровая вода – поверхностный слой донных отложений» прибрежной зоны восточной части Финского залива в весенне-летний период // Известия Томского политехнического университета. Инжиниринг георесурсов. – 2022. – Т. 333. – № 1. – С. 95-104
Актуальность исследования обусловлена необходимостью изучения вторичного загрязнения водной среды металлами в весенне-летнее время, когда активизируются разнообразные биогеохимические процессы, влияющие на изменение физико-химического состояния поверхностного слоя донных отложений. Цель: изучение закономерностей образования и миграции растворимых форм металлов в системе «донные отложения – поровая вода – придонная вода» в весенне-летнее время в прибрежной зоне восточной части Финского залива. Объекты: пробы поверхностного слоя донных отложений, поровой и придонной воды пяти станций прибрежной зоны восточной части Финского залива. Методы: потенциометрический метод определения pH и Eh в донных отложениях и придонной воде. Валовые концентрации Fe, Zn, Cd, Pb, Cu в донных отложениях определяли методом масс-спектрометрии с индуктивно-связанной плазмой (ICP-MS). Концентрации растворенных форм металлов (Fe, Cu, Cd, Zn, Pb) в поровой, придонной водах определяли методом масс-спектрометрии с индуктивно-связанной плазмой на приборе «Agilent 7700x» (фирма «Agilent Technologies»). Результаты. Установлены закономерности образования и миграции растворимых форм металлов на границе «донные отложения – вода» в прибрежной зоне восточной части Финского залива в зависимости от изменений температуры, кислородного режима в придонных водах и окислительно-восстановительных процессов, формирующихся в поверхностном слое донных отложений. Показано, что в конце весеннего сезона в донных отложениях восточной части Финского залива устанавливаются восстановительные условия, способствующие восстановлению гидроксидов железа, накопившихся на дне. В результате возникает поток растворенных форм Fe, Cu, Zn, Cd, Pb в поровые и придонные слои воды. В июле загрязненность поровых и придонных вод всеми изученными металлами снижается.
ОЦЕНКА СРОКА СЛУЖБЫ ИЗОЛЯЦИИ КАБЕЛЬНЫХ ИЗДЕЛИЙ ДЛЯ СИСТЕМ ПИТАНИЯ И УПРАВЛЕНИЯ ГОРНОШАХТНОГО ЭЛЕКТРООБОРУДОВАНИЯ
Authors: Леонов Андрей Петрович , Солдатенко Татьяна Михайловна 
Published: January 2022

Ссылка для цитирования: Леонов А.П., Солдатенко Т.М. Оценка срока службы изоляции кабельных изделий для систем питания и управления горношахтного электрооборудования // Известия Томского политехнического университета. Инжиниринг георесурсов. – 2022. – Т. 333. – № 1. – С. 113-120.
Актуальность исследования обусловлена повышением требований к эксплуатационным свойствам гибких кабелей, применяемых в системах питания и управления горношахтного электрооборудования. Основным направлением, обеспечивающим улучшение свойств, является применение новых электроизоляционных материалов. На сегодняшний день шахтные кабели изготавливаются преимущественно с изоляцией из резины. Перспективным решением в плане совершенствования конструкций гибких шахтных кабелей является применение этиленпропиленовой резины, обладающей более высокой нагревостойкостью по сравнению с применяемыми резинами на основе хлоропренового и бутилкаучука. Повышение допустимой температуры нагрева токопроводящих жил позволит повысить передаваемую мощность, высокие значения тока термической устойчивости при коротком замыкании с обеспечением требуемой гибкости. Практическое применение кабелей нового типа в системах горношахтного электрооборудования невозможно без экспериментального подтверждения ресурсных характеристик. Отсутствие в технической литературе рекомендаций по проведению подобных испытаний определяет необходимость исследований, позволяющих прогнозировать срок службы гибких кабелей с учетом изменения физико-механических свойств этиленпропиленовой резины. Цель: разработать методику и определить срок службы гибких кабельных изделий с изоляцией из этиленпропиленовой резины для систем питания и управления горношахтного электрооборудования. Объект: гибкий шахтный кабель, изоляция, этиленпропиленовая резина, физико-механические свойства, энергия активации, срок службы. Методы: экспериментальные методы оценки физико-механических свойств и теплостойкости полимерных материалов; математические методы решения нелинейных систем уравнений и статистический анализ результатов испытаний. Результаты. Разработана методика определения срока службы кабелей с изоляцией из этиленпропиленовой резины, основанная на методе прогнозирования изменения физико-механических свойств с учетом энергии активации Ea процессов термической деструкции. Определен срок службы гибких шахтных кабелей с учетом температуры.
Message from the Editor in Chief
Authors: Laborda Jesus Garcia 
Published: January 2022

It is our pleasure to publish the Volume 11, Number 3 of the Global Journal of Foreign Language Teaching. The study of various methods of teaching foreign languages has been on the rise in recent years. The current issue aims to present to our readers, some of these shifts in the methods of teaching foreign languages around the world.
After a careful peer review process, six articles were selected. The selected articles include : “The necessity of learning English in multilingual Algeria: Belhadj Bouchaib University as a case study”; “Comparative effects of partial dictation and dictogloss on listening comprehension ability of EFL learners”; “Letting students decide whether to work in pairs or individually in class”; “The perception of Nigerian students of German about serious games”: “Using ‘Secret of the Sky Disc’ as a case study”; “Cross-country comparison of foreign language curriculum in Germany, Spain and Turkey”. The authors of these papers represent Turkey, Nigeria, Portugal, Algeria, Iran and India.
We trust this publication would be beneficial to all our readers. We would therefore like to thank all our contributors who made this publication a success. Dear reader, enjoy reading!!
Best Regards,
Jesus Garcia Laborda, University of Alcala, Spain,
Editor-in-chief.
Wacana Poros Partai Islam untuk PILPRES 2024: Politik Identitas atau Penggalangan Suara Oposisi?
Authors: Hamdanny Daniel Rusyad , Mukhtar Khoiruddin 
Published: January 2022

<p><em>Amidst increasing polarization of society after the 2014 and 2019 presidential elections, identity politics has been reintroduced by Islamic political parties. PKS and PPP are trying to initiate the Islamic pollitical axis for 2024 elections. The discourse about Islamic political axis springs due to the fact that incumbents cannot re-nominate as president for next election. Secondly, public trust level toward the executive has decreased due to various unpopular policies that brought about increasing critical voices toward the government. From the internal ummah, the presence of Islamic political figures who consitently won various surveys, stimulates the passion of Islamic political parties to form coalitions to win 2024 presidential election. This study uses a qualitative approach with content analysis methods toward various sources of literature; book, ebook, scientific journals, articles on conference proceedings, as well as journalistic works on the Islamic political axis discourse from identity politics theory, and theories of party coalition’s perspective that introduced by Lijphart and Rikers. The phenomenon of the coalition of Islamic political parties – once called the center axis – has succeeded in bringing KH Abdurrahman Wahid as President, defeating the candidate of the party that won the 1999 election. The similarity of identity (ideological) and interests (pragmatic) became the basis of the coalition of Islamic political parties. In addition to these two reasons, the discourse of the Islamic axis coalition in the 2024 election is also motivated by dissatisfaction with the performance and policies of the incumbent government. The regulation of the Presidential Threshold for presidential candidacy as stated by law number 7 year 2017 makes the coalition of Islamic political parties can be function as an alternative house in accomodating opposition voices. However, the elite of Islamic political parties is divided in responding to the discourse of the Islamic political axis. PKS, PPP, PKB. PBB, and Masyumi (Reborn) supports the idea of </em><em></em><em>a coalition based on political calculations and the interests of each political party. On the other hand, PAN and the Gelora Party reject the discourse which is worried to be increasing polarization in Indonesian society. The Ummat Party's skepticism is backed by the view that the existing parliamentary Islamic political parties are not serious to grasp the aspirations of the ummah and have not been able to offer alternative policies for a better Indonesia. </em></p>
An Assessment of Zakat Contributions for Productive Purposes to Empower the Mustahik Economy in the Face of the Covid-19 Pandemic
Authors: Hamidah Raisa Aribatul , Alam Azhar , Anggraeni Arum , Nizam Renaldi Sahrul 
Published: January 2022

<p><em>People have lost their jobs as a result of the Covid-19 pandemic, and many people are now living in poverty. Zakat is one of the Islamic pillars concerned with poverty reduction, particularly in the form of productive disbursement. The purpose of this research is to identify and assess the mechanisms and contributions of productive zakat to economic empowerment mustahik during the covid-19 pandemics. Zakat for productive purposes is wealth that enables the recipient to continuously create creativity using zakat funds. This study conducted in-depth interviews with three Zakat institution staff and seven mustahik who live in a low-income society and are economically impacted by covid-19. This study used the descriptive method, with data retrieval in this study using the interview method, followed by data analysis in the form of data reduction, data presentation, and conclusions. According to the findings of this study, there are still a limited number of Human Resources available for mustahik coaching and supervision at LAZISMU Pemalang. This paper discovered that not all mustahik use 100 percent of productive zakat funds to develop the business as hoped, but instead meet basic needs. Mustahik primarily requires more fulfillment with short-term benefits in order to sustain their lives. </em></p>
Engineered Exosomes for the Targeted Delivery of A Novel Therapeutic Cargo to Enhance Sorafenib-Mediated Ferroptosis in Hepatocellular Carcinoma.
Authors: Li Xiaoju , yu Qianqian , Guo Xinyan , Liu Chenlin , Zhao Runze , Zhang Kuo , Zhang Wangqian , Liu Jinghan , Sun guanchao , Wang Shuning , Hao Qiang , Li Weina , Li Meng , Zhang Yingqi , Zhang Cun , gao yuan 
Published: January 2022

Abstract
Background

Sorafenib is one of the few effective first-line drugs approved for the treatment of advanced hepatocellular carcinoma (HCC). However, the development of drug resistance is common among individuals with HCC. Thus, there is an urgent need to solve this problem.
Results

Recent evidence indicated that the anticancer activity of sorafenib mainly relies on the induction of ferroptosis. In our study, genes that suppress ferroptosis, especially GPX4 and DHODH, were enriched in sorafenib-resistant cells and primary tissues and were associated with poor prognosis of HCC patients who received sorafenib treatment. Therefore, silencing GPX4 and DHODH might be a new and effective strategy to overcome sorafenib resistance. Here, a new ferroptosis inducer comprising a multiplex small interfering RNA (multi-siRNA) capable of simultaneously silencing GPX4 and DHODH was created. Then, exosomes with high multi-siRNA loading and HCC-specific targeting were established by fusing the SP94 peptide and the N-terminal RNA recognition motif (RRM) of U1-A with the exosomal membrane protein Lamp2b. The results from the in vitro and in vivo experiments indicate that this tumor-targeting nanodelivery system (ExoSP94−lamp2b−RRM-multi-siRNA) could enhance sorafenib-induced ferroptosis and overcome sorafenib resistance, which might open a new avenue for clinically overcoming sorafenib resistance.
Conclusions

We designed HCC-targeted exosomes (ExoSP94−Lamp2b−RRM) that can deliver a new ferroptosis inducer. Our data show that ExoSP94−lamp2b−RRM-multi-siRNA could enhance sorafenib-induced ferroptosis by silencing GPX4 and DHODH expression and consequently increase HCC sensitivity to sorafenib. This is the first study to describe the use of engineered exosomes to overcome acquired sorafenib resistance with respect to ferroptosis.
Comparison of Clinical Features of Acute Esophageal Mucosal Lesions and Those of Reflux Esophagitis Los Angeles Classification Grade D
Authors: Ichita Chikamasa , Sasaki Akiko , Sumida Chihiro , Nishino Takashi , Kubota Jun , Kimura Karen , Shionoya Kento , Makazu Makomo , Masuda Sakue , Koizumi Kazuya , Kako Makoto 
Published: January 2022

Abstract
Background: Acute esophageal mucosal lesions (AEMLs) cause circumferential mucosal damage in the lower esophagus in patients with deteriorating general health. However, its etiology remains unclear. AEML is often diagnosed and treated as severe reflux esophagitis (sRE), particularly that of Los Angeles classification grade D (sRE-D). This study aimed to determine whether it is appropriate to classify these two diseases according to the characteristics of the proximal mucosa of erosion as previously reported, and to clarify the clinical features of AEML in comparison with sRE-D.Methods: Patients were classified into AEML and sRE-D groups, based on previous reports. Patient background, presence of shock, medical history, medications, comorbidities, death during hospitalization, blood sampling data, endoscopic findings, and presence of stenosis after treatment were evaluated.Results: There were significantly more cases with comorbidities in the AEML group than in the sRE-D group, particularly comorbidities involving infectious diseases. In addition, abnormalities in blood test results were significantly more frequent in the AEML group than in the sRE-D group. This suggests that the onset of AEML may be due to peripheral circulatory disturbance caused by worsening general condition.Conclusions: AEML and sRE-D showed distinctly different features and it was considered reasonable to distinguish them. AEML, unlike sRE-D, may be caused by microcirculatory disturbances related to comorbidities rather than gastric acid reflux. However, it is under-recognized and should be considered in the setting of upper gastrointestinal bleeding in patients with deteriorating general condition.
Coprecipitation Aided Synthesis of Bimetallic Silver Tungstate: A Response Surface Simulation of Sunlight-Driven Photocatalytic Removal of 2,4-dichlorophenol
Authors: Rakshitha Rajashekara , Gurupadayya Bannimath , Devi Sake Haridass Kameshwari , Pallavi Nagaraju 
Published: January 2022

Abstract
In the present study, the Response Surface Methodology (RSM) model was used to investigate the photocatalytic performance of silver tungstate (Ag2WO4) in the removal of 2,4-dichlorophenol (2,4-DCP) under natural sunlight. The Ag2WO4 which has nanoflower-like structure was synthesized by a coprecipitation method. The synthesized photocatalyst was characterized for FESEM, TEM, EDX, XRD, FTIR, and UV-Vis spectroscopy. RSM was employed to scrutinize the suitable model to yield a profound pollutant removal rate. The four independent factors such as pollutant concentration, catalyst dosage, pH, and contact time are simulated using RSM. 91% of 2,4-DCP degradation was achieved at a higher catalyst dosage and lower pollutant concentration with contact duration of 8 h in an alkaline pH condition. The coefficient of regression (R2) and probability value (P) were 0.98 and 0.0472, respectively, which confirmed the ideality of RSM modeling. The study discusses on the possible photocatalytic degradation mechanisms of 2, 4-DCP. The results showed a significant dependence of the photocatalytic removal of 2, 4-DCP on the functional parameters.
Ketogenic Diet Modulates Neuroinflammation via Metabolites from Lactobacillus reuteri after Repetitive Mild Traumatic Brain Injury in Adolescent Mice
Authors: Dilimulati Dilirebati , Zhang Fengchen , Shao Shuai , Lv Tao , Lu Qing , Cao Mengqiu , Jin Yichao , Jia Feng , Zhang Xiaohua 
Published: January 2022

Abstract
Repetitive mild traumatic brain injury (rmTBI) is associated with a range of neural changes which is characterized by axonal injury and neuroinflammation. Ketogenic diet (KD) is regarded as a potential therapy for facilitating recovery after moderate-severe traumatic brain injury (TBI). However, its effect on rmTBI has not been studied. In this study, we evaluated the anti-neuroinflammation effects of KD after rmTBI in adolescent mice and explored the potential mechanisms. Experimentally, specific pathogen-free (SPF) adolescent male C57BL/6 mice received a sham surgery or repetitive mild controlled cortical impacts consecutively for 7 days. The uninjured mice received the standard diet, and the mice with rmTBI were fed either the standard diet or KD for 7 days. One week later, all mice were subjected to behavioral tests and experimental analysis. Results suggest that KD significantly increased blood beta-hydroxybutyrate (β-HB) levels and improved neurological function. KD also reduced white matter damage, microgliosis and astrogliosis induced by rmTBI. Aryl hydrocarbon receptor (AHR) signaling pathway, which was mediated by indole-3-acetic acid (3-IAA) from Lactobacillus reuteri (L. reuteri) in gut and activated in the microglia after rmTBI, was inhibited by KD. The expression level of the toll-like receptor 4 (TLR4)/myeloid differentiation primary response 88 (MyD88) in microglial cells, which mediates the NF-κB pathway, was also attenuated by KD. Taken together, our results indicated that KD can promote recovery following rmTBI in adolescent mice. KD may modulate microgliosis and activation by altering L. reuteri in gut and its metabolites. The inhibition of indole/AHR pathway and the downregulation of TLR4/MyD88 may play a role in the beneficial effect of KD against neuroinflammation in rmTBI mice.
GAS5 Attenuates Malignant Progression of Glioma Stem-like Cells via Regulating E-cadherin
Authors: Wang Haiyang , Wang Ding , Shen Yongfeng , Sun Chenglong , Hu Qiang , Jiang Li , Du Quan 
Published: January 2022

Abstract
Background: It is commonly understood that glioma stem-like cells (GSCs) play a vital role in the malignant progression of glioma. Recent studies have reported that long non-coding RNAs (lncRNAs) closely associate with glioma development, however, the underlying molecular regulatory mechanisms on GSCs have not been fully clarified. Methods: LncRNA GAS5 expression level was analyzed by bioinformatics and qRT-PCR assays. GSCs were separated from glioma tissues and identified using immunofluorescence and flow cytometry. Cell proliferation ability was measured by EdU assays. Cell invasion and migration ability was evaluated by transwell assays. Cell apoptosis was measured by flow cytometry. Subcutaneous tumorigenesis assays were performed to explore the GSCs growth in vivo. Luciferase reporter assays were used to identify the direct molecular interaction. E-cadherin expression level was measured by qRT-PCR assays and western blot.Results: In this study, we established two highly malignant glioma stem-like cells from clinical surgical specimens, and found that lncRNA GAS5 was downregulated in GSCs and high-grade glioma tissues, and showed a correlation with patient survival. Functional assays showed that depleting GAS5 promoted the proliferation, invasion, migration, stemness and tumorigenicity, and inhibited apoptosis of GSCs. Mechanistically, GAS5 directly sponge with miR-23a which acts as an oncogene by regulating E-cadherin (CDH1). In addition, rescue experiments demonstrated that GAS5 modulate both the expression and function of E-cadherin via the dependent manner of miR-23a. Conclusions: GAS5 functions as a suppressor in GSCs by targeting the miR-23a/CDH1 axis, which may be a promising therapeutic target against gliomas.
Long-Term Behavior of Tropospheric Temperatures in Jupiter:
Evidence for Quasi-Seasonal and Non-Seasonal Variability
Authors: Orton Glenn , Antuñano Arrate , Fletcher Leigh , Sinclair James , Momary Thomas , Fujiyoshi Takuya , Yanamandra-Fisher Padma , Donnelly Padraig , Greco Jennifer , Payne Anna , Boydstun Kimberly , Wakefield Laura 
Published: January 2022

Abstract
A four-decade study of ground-based mid-infrared observations of Jupiter covering three and a half of its solar orbits over ±30° of latitude has revealed unexpected variations of upper-tropospheric temperatures. Patterns of variability with 10-14 year periods at discrete latitudes were discovered, all within ±2 years of Jupiter’s 11.9-year orbital period. Their repeated pattern of temperature variations is strongly anticorrelated between conjugate latitudes at 16°, 22° and 30° from the equator, latitudes too low to be significantly influenced by seasonal solar forcing. A strong temperature periodicity of 8-9 years is limited to within 10° of the equator. Another periodicity of 7 years covers a wide range of latitudes. A weaker but significant 4-year period covers latitudes from 10°S to 30°N. The 4- and 8-9-year periods at 330 mbars appear to be correlated with those 60-70 km higher in the stratosphere near ~10 mbar, with a ~2-year delay from the stratospheric to the tropospheric level, suggesting a top-down control of tropospheric temperatures by radiative processes in Jupiter’s stratosphere. Correlations between temperature variability and changes in visible appearance of clouds were also detected in Jupiter’s South Equatorial Belt (6°S-17°S) and North Equatorial Belt (6-15°N). No variability was detected at periods longer than 14 years.