bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determining the role and responsibilities of the community epilepsy nurse in the management of epilepsy
Authors: Hutchinson Karen , Ryder Tayhla , Coleman Honor , Nullwala Ruqaiya , Herkes Geoffrey , Bleasel Andrew , Nikpour Armin , Wong Chong , Todd Lisa , Ireland Carol , Shears Graeme , Bartley Melissa , Groot Wendy , Kerr Michael , Vagholkar Sanjyot , Braithwaite Jeffrey , Rapport Frances 
Published: December 2022

AbstractAims and ObjectivesThe aim of this study is to enhance the understanding of the core elements and influencing factors on the community‐based epilepsy nurse's role and responsibilities.BackgroundInternationally, epilepsy nurse specialists play a key role in providing person‐centred care and management of epilepsy but there is a gap in understanding of their role in the community.DesignA national three‐stage, mixed‐method study was conducted.MethodsOne‐on‐one, in‐depth semi‐structured qualitative interviews were conducted online with 12 community‐based epilepsy nurses (Stage 1); retrospective analysis of data collected from the National Epilepsy Line, a nurse‐led community helpline (Stage 2); and focus group conducted with four epilepsy nurses, to delve further into emerging findings (Stage 3). A thematic analysis was conducted in Stages 1 and 3, and a descriptive statistical analysis of Stage 2 data. Consolidated Criteria for Reporting Qualitative studies checklist was followed for reporting.ResultsThree key themes emerged: (1) The epilepsy nurse career trajectory highlighted a lack of standardised qualifications, competencies, and career opportunities. (2) The key components of the epilepsy nurse role explored role diversity, responsibilities, and models of practice in the management of living with epilepsy, and experiences navigating complex fragmented systems and practices. (3) Shifting work practices detailed the adapting work practices, impacted by changing service demands, including COVID‐19 pandemic experiences, role boundaries, funding, and resource availability.ConclusionCommunity epilepsy nurses play a pivotal role in providing holistic, person‐centred epilepsy management They contribute to identifying and addressing service gaps through innovating and implementing change in service design and delivery.Relevance to Clinical PracticeEpilepsy nurses' person‐centred approach to epilepsy management is influenced by the limited investment in epilepsy‐specific integrated care initiatives, and their perceived value is impacted by the lack of national standardisation of their role and scope of practice.No Patient or Public ContributionOnly epilepsy nurses' perspectives were sought.
Beliefs Aggregation and Return Predictability
Authors: KYLE ALBERT S. , OBIZHAEVA ANNA A. , WANG YAJUN 
Published: December 2022

ABSTRACTWe study return predictability using a model of speculative trading among competitive traders who agree to disagree about the precision of private information. Although traders apply Bayes' Law consistently, returns are predictable. In addition to trading on long‐term fundamental value, traders also trade on perceived short‐term opportunities arising from foreseen future disagreement, as in a Keynesian beauty contest. Contradicting conventional wisdom, this short‐term speculation dampens price fluctuations and generates time‐series momentum. Model calibration shows quantitatively realistic patterns of return dynamics. Consistent with empirical evidence, our model predicts more pronounced momentum for stocks with higher trading volume.
Bayesian Solutions for the Factor Zoo: We Just Ran Two Quadrillion Models
Authors: BRYZGALOVA SVETLANA , HUANG JIANTAO , JULLIARD CHRISTIAN 
Published: December 2022

ABSTRACTWe propose a novel framework for analyzing linear asset pricing models: simple, robust, and applicable to high‐dimensional problems. For a (potentially misspecified) stand‐alone model, it provides reliable price of risk estimates for both tradable and nontradable factors, and detects those weakly identified. For competing factors and (possibly nonnested) models, the method automatically selects the best specification—if a dominant one exists—or provides a Bayesian model averaging–stochastic discount factor (BMA‐SDF), if there is no clear winner. We analyze 2.25 quadrillion models generated by a large set of factors and find that the BMA‐SDF outperforms existing models in‐ and out‐of‐sample.
Parents' work arrangements and gendered time use during the COVID‐19 pandemic
Authors: Lyttelton Thomas , Zang Emma , Musick Kelly 
Published: December 2022

AbstractObjectiveThis study uses time diaries to examine how parents' work arrangements shaped their time use at home and work during the COVID‐19 pandemic.BackgroundThe pandemic transformed home and work life for parents, disrupting employment and childcare. The shift to work from home offered more flexibility to manage increased care burdens, but the lack of separation between work and family also likely contributed to more challenging work environments, especially among mothers.MethodThis study relies on the 2017–2020 American Time Use Survey and matching to estimate changes in time use among parents working from home and on site in the pandemic relative to comparable parents prior to the pandemic.ResultsData showed no overall increases in primary childcare time among working parents. Parents working from home during the pandemic, however, spent more time in the presence of children and supervising children, much in combination with paid work. Mothers working from home increased their supervisory parenting while working for pay more than fathers, and they more often changed their paid work schedules. The study's main findings were robust to gendered unemployment and labor force exits.ConclusionParents, especially mothers, working from home responded to childcare demands through multitasking and schedule changes with potential negative effects on work quality and stress. Parents working on site during the pandemic experienced smaller changes in time use.ImplicationsThe pandemic has generated new inequalities between those with and without the flexibility to work from home, and exacerbated gender inequalities among those working from home.
Paradox, Dialectics or Trade‐Offs? A Double Loop Model of Paradox
Authors: Berti Marco , Cunha Miguel Pina e 
Published: December 2022

AbstractParadox literature is emerging as one of the most vital streams in management studies, but it is affected by some growing pains. First, the concept of paradox is still too fuzzy, which impacts empirical research and hinders communication with other literatures. Second, the assumption that paradoxes are always best met with acceptance and search for balance is problematic because it limits the heuristic potential of a paradox lens, because it constrains the range of sustainable responses to contradictions, and because it may induce to appeasement in face of injustice. In this paper we propose to strengthen paradox theory by incorporating the contributions of two alternative perspectives on organizational tensions: trade‐offs and dialectics. We thus present a model which expands organizational paradox theory by: (1) clarifying the concept of organizational paradox; and (2) offering a model that better describes the varied phenomenology, causes and consequences of organizational tensions and paradoxes.
Identity Conflict Amidst Environmental Change: An Ethnography of a Korean Buddhist Temple
Authors: Song Hee‐Chan 
Published: December 2022

AbstractDrawing on a Buddhist context, this study examines how societal‐level environmental changes trigger internal identity conflict within a temple between its traditional identity as a silent meditative space for monks and its emerging identity as an open cultural space for people. It investigates the long‐term adaptive process through which the conflict has been recognized and managed amid the environmental changes. The findings reveal that the identity conflict gradually led to the formation of two subgroups of monks: a sacred meditator group and a cultural service provider group. While this separation created mild tension between the subgroups, it paradoxically enabled the temple to simultaneously seek two opposing goals: spiritual meditation practice and cultural service. Consequently, the temple continues to pursue the traditional way of monastic life, while responding to the changing societal demands on religion. These findings extend our understanding of how organizational identity conflict is recognized, interpreted, and managed in response to environmental changes. In particular, they elucidate the link between identity and institutional processes by showing how organizational members, not necessarily through the leaders' agentic actions, spontaneously and organically cope with identity conflict triggered by external changes.
Theorizing the Grey Area between Legitimacy and Illegitimacy
Authors: Siraz Sonia S. , Claes Björn , De Castro Julio O. , Vaara Eero 
Published: December 2022

AbstractDespite a proliferation of research on legitimacy, the ‘grey area’ that lies between legitimacy and illegitimacy remains undertheorized. Responding to calls for further research, we clarify the construct of legitimacy and extend legitimacy theory by providing a conceptual framework for analyzing the legitimacy‐illegitimacy continuum. First, we propose three novel legitimacy states between legitimacy and illegitimacy – conditional legitimacy, unknown legitimacy, and conditional illegitimacy – and elaborate on the distinct qualitative characteristics of the five legitimacy states. Second, we offer a model of the dynamics of legitimacy state change and the (in)stability of the issue‐specific reference framework that is used to judge them. Third, we explain how our legitimacy states bridge the research streams on legitimacy judgment formation and legitimation strategies. By doing so, we integrate these research streams and enumerate discursive strategies for each state. Our article contributes to a more robust understanding of both how legitimacy states can be conceptualized and analyzed in future research and how they can be dealt with in managerial practice.
Short‐term neurochemical effects of transcutaneous trigeminal nerve stimulation using 7T magnetic resonance spectroscopy
Authors: Ritland Bradley M. , Neumeier William H. , Jiang Sam H. , Smith Carl D. , Heaton Kristin J. , Hildebrandt Audrey M. , Jabbar Muhammad A. , Liao Hui Jun , Coello Eduardo , Zhao Wufan , Bay Camden P. , Lin Alexander P. 
Published: December 2022

AbstractBackground and PurposeThe purpose was to explore the effects of transcutaneous trigeminal nerve stimulation (TNS) on neurochemical concentrations (brainstem, anterior cingulate cortex [ACC], dorsolateral prefrontal cortex [DLPFC], ventromedial prefrontal cortex [VMPFC], and the posterior cingulate cortex [PCC]) using ultrahigh‐field magnetic resonance spectroscopy.MethodsThis double‐blinded study tested 32 healthy males (age: 25.4 ± 7.3 years) on two separate occasions where participants received either a 20‐minute TNS or sham session. Participants were scanned at baseline and twice post‐TNS/sham administration.ResultsThere were no group differences in concentration changes of glutamate, gamma‐aminobutyric acid, glutamine, myoinositol (mI), total N‐acetylaspartate, total creatine (tCr), and total choline between the baseline scan and the first post‐TNS/sham scan and between the first and second post‐TNS/sham scan in the brainstem, ACC, DLPFC, VMPFC, and PCC. Between the baseline scan and the second post‐TNS/sham scan, changes in tCr (mean difference = 0.280 mM [0.075 to 0.485], p = .026) and mI (mean difference = 0.662 mM [0.203 to 1.122], p = .026) in the DLPFC differed between groups. Post hoc analyses indicated that there was a decrease in tCr (mean change = –0.201 mM [–0.335 to –0.067], p = .003) and no change in mI (mean change = –0.327 mM [–0.737 to 0.083], p = .118) in the TNS group; conversely, there was no change in tCr (mean change = –0.100 mM [–0.074 to 0.274], p = .259) and an increase in mI (mean change = 0.347 mM [0.106 to 0.588], p = .005) in the sham group.ConclusionThese data demonstrate that a single session of unilateral TNS slightly decreased tCr concentrations in the DLPFC region.
The effects of socioeconomic status on personality development in adulthood and aging
Authors: Luo Jing , Zhang Bo , Antonoplis Stephen , Mroczek Daniel K. 
Published: December 2022

AbstractIntroThe current study examined the effects of adulthood socioeconomic status (SES) on levels of and changes in the Big Five personality traits domains and nuances in adulthood and during aging. We also tested whether the relations between adulthood SES and personality traits differed by childhood SES and age.MethodsData were drawn from three longitudinal studies: the Swedish Adoption/Twin Study of Aging (SATSA, N = 2000), the Midlife in the United States (MIDUS, N = 6428), and the Health and Retirement Study (HRS, N = 23,238).ResultsUsing the latent growth models, across samples, we found associations between high SES and low levels of neuroticism and high levels of extraversion, openness, and conscientiousness. The effects of SES on changes in personality traits were mainly observed in the aging sample of HRS. In general, a similar pattern was observed at the nuance level. Analyses of the moderating effects of age suggested some evidence for the increasingly important role of SES in levels of and changes in personality traits in older ages.ConclusionThe findings support SES as a source that partially accounts for individual differences in personality traits level. Some evidence was found for the relations between SES and changes in personality traits in old age.
Cladosporium species causing leaf spot on silage maize based on multi‐locus phylogeny in China
Authors: Qi Hexing , Lu Guangxin , Li Zongren , Xu Chengti , Tian Feng , He Chenbang , Ma Guihua , Ma Weili , Ma Haixia 
Published: December 2022

AbstractQinghai Province is one of China's five major pastoral areas located in the northeastern part of the Qinghai‐Tibet Plateau, and animal husbandry plays a great part in the local economy. One of the most important crops in Qinghai Province is maize for silage, which sustains ecological animal husbandry. However, the leaf spot disease of maize has seriously impeded the healthy development of the maize industry. We found that from 2019 to 2020 leaf spot of silage maize caused by Cladosporium was a common disease in Qinghai Province. This leaf spot disease formed water‐soaked round or irregular spots at the early stage and gradually expanded to black at the later stage, and the incidence of the leaf spot in the fields reached 15%–45%. In this study, 125 isolates were isolated from seven locations in Qinghai Province, with 123 isolated from leaves and two isolated from bracts of maize for silage. Their phylogeny, morphology, and pathogenicity were analysed to identify pathogens and investigate the differences among them. Based on phylogenetic analysis of multi‐locus (ITS, actin, and translation elongation factor (1‐α)) sequences and morphology characteristics, the 125 isolates were identified to belong to eight species of Cladosporium: C. allicinum, C. cladosporioides, C. xylophilum, C. herbarum, C. macrocarpum, C. asperulatum, C. subinflatum, and C. floccosum. Pathogenicity tests by artificial inoculation demonstrated that 125 isolates were pathogenic on eight maize cultivars for silage, and pathogenicity differentiation was not observed. Taken together, our results demonstrated that these eight species of Cladosporium caused leaf spot disease of maize in Qinghai Province. This is the first analysis report on Cladosporium species from maize in China, and our findings provide a theoretical foundation for the management of this disease in the future.
Lipase‐a single‐nucleotide polymorphism rs143793106 is associated with increased risk of aggressive periodontitis by negative influence on the cytodifferentiation of human periodontal ligament cells
Authors: Matsumoto Masahiro , Fujihara Chiharu , Nantakeeratipat Teerachate , Kitagaki Jirouta , Yamamoto Yu , Yamada Satoru , Kitamura Masahiro , Murakami Shinya 
Published: December 2022

AbstractBackground and ObjectiveAggressive periodontitis (AgP) is characterized by general health and rapid destruction of periodontal tissue. The familial aggregation of this disease highlights the involvement of genetic factors in its pathogeny. We conducted a genome‐wide association study (GWAS) to identify AgP‐related genes in a Japanese population, and the lipid metabolism‐related gene, lipase‐a, lysosomal acid type (LIPA), was suggested as an AgP candidate gene. However, there is no report about the expression and function(s) of LIPA in periodontal tissue. Hence, we studied the involvement of how LIPA and its single‐nucleotide polymorphism (SNP) rs143793106 in AgP by functional analyses of LIPA and its SNP in human periodontal ligament (HPDL) cells.Materials and MethodsGWAS was performed using the genome database of Japanese AgP patients, and the GWAS result was confirmed using Sanger sequencing. We examined the mRNA expression level of LIPA and the protein expression level of the encoded protein lysosomal acid lipase (LAL) in periodontium‐composing cells using conventional and real‐time polymerase chain reaction (PCR) and western blotting, respectively. Lentiviral vectors expressing LIPA wild‐type (LIPA WT) and LIPA SNP rs143793106 (LIPA mut) were transfected into HPDL cells. Western blotting was performed to confirm the transfection. LAL activity of transfected HPDL cells was determined using the lysosomal acid lipase activity assay. Transfected HPDL cells were cultured in mineralization medium. During the cytodifferentiation of transfected HPDL cells, mRNA expression of calcification‐related genes, alkaline phosphatase (ALPase) activity and calcified nodule formation were assessed using real‐time PCR, ALPase assay, and alizarin red staining, respectively.ResultsThe GWAS study identified 11 AgP‐related candidate genes, including LIPA SNP rs143793106. The minor allele frequency of LIPA SNP rs143793106 in AgP patients was higher than that in healthy subjects. LIPA mRNA and LAL protein were expressed in HPDL cells; furthermore, they upregulated the cytodifferentiation of HPDL cells. LAL activity was lower in LIPA SNP‐transfected HPDL cells during cytodifferentiation than that in LIPA WT‐transfected HPDL cells. In addition, ALPase activity, calcified nodule formation, and calcification‐related gene expression levels were lower during cytodifferentiation in LIPA SNP‐transfected HPDL cells than those in LIPA WT‐transfected HPDL cells.ConclusionLIPA, identified as an AgP‐related gene in a Japanese population, is expressed in HPDL cells and is involved in regulating cytodifferentiation of HPDL cells. LIPA SNP rs143793106 suppressed cytodifferentiation of HPDL cells by decreasing LAL activity, thereby contributing to the development of AgP.
Effects of a single subcutaneous dose of enoxaparin on veterinary viscoelastic coagulation monitor variables in healthy cats: Double blind, placebo controlled cross‐over trial
Authors: Yozova Ivayla D. , Kent Michael S. , Jandrey Karl E. 
Published: December 2022

AbstractBackgroundCats placed on anticoagulant medication require frequent monitoring. The veterinary viscoelastic coagulation monitor (VCM‐Vet) could provide a convenient and cost‐effective monitoring, enabling therapeutic decision making.Hypothesis/ObjectivesEnoxaparin will lead to changes in VCM‐Vet variables and these will correlate with antiXa activity.AnimalsTwenty‐one healthy cats.MethodsCats were randomized to receive either enoxaparin (1 mg/kg) subcutaneously or 0.9% NaCl (equal volume) and crossed over with a 7‐day washout period. The investigators were blinded to group allocation until data analysis. Jugular blood samples were drawn at time 0, and 2, 4, and 8 hours after injection for VCM‐Vet analysis within 2 min of collection. Citrated plasma was frozen at −80°C for antiXa activity analysis. A Generalized Linear Model was completed to assess changes between baseline measurements and all time points.ResultsSignificant differences between the enoxaparin‐treated cats and controls at for T0h and T2h were found and presented as mean ± SD for clotting time (enoxaparin, 593.4 ± 78.0 s; control, 448.5 ± 50.3 s, P < .001), clot formation time (enoxaparin, 183.1 ± 41.7 s; control, 155.4 ± 28.0 s, P = .001), and alpha angle (enoxaparin, 52.4 ± 6.1°; control, 56.9 ± 3.7 s, P = .003). AntiXa activity was significantly different between T0 and all other timepoints for the enoxaparin group (P < .001). There was no correlation between changes in clotting time and antiXa activity.Conclusions and Clinical ImportanceThe VCM‐Vet detects a difference at 2 hours after single‐dose enoxaparin administration and it can be useful for anticoagulant therapy monitoring in cats.
Aggression and burnout in nurses during COVID‐19: A cross‐sectional study
Authors: Molero Jurado María del Mar , Gázquez Linares José Jesús , Pérez‐Fuentes María del Carmen , Martos Martínez África 
Published: December 2022

AbstractWorkplace violence against nurses, an ever‐present problem in the healthcare workplace, has been increasing with COVID‐19 and affects occupational health. This study analyzed the consequences of COVID‐19 on violence against nurses, identifying its association with burnout, emphasizing the importance of work‐related variables. A total of 1013 actively employed nurses in Spain with a mean age of 34.71 years filled out a computer‐assisted web interviewing survey. Aggression as a consequence of their work was reported by 73.44% of the nurses. Those most affected were in primary care, and verbal aggression by patients and their families was the most frequent. Nurses who were attacked scored significantly higher in emotional exhaustion and depersonalization. Furthermore, 83.22% said that COVID‐19 was an important factor in the increase in violence toward healthcare workers. Analysis showed that a perceived secure environment was a mediator between the belief that COVID‐19 was an influential factor in the increase of violence and the depersonalization dimension of burnout. Increasing perceived security in the work environment among nurses can be effective in promoting well‐being, work performance, and commitment to the profession.
MUS81 is required for atypical recombination intermediate resolution but not crossover designation in rice
Authors: Mu Na , Li Yafei , Li Sanhe , Shi Wenqing , Shen Yi , Yang Han , Zhang Fanfan , Tang Ding , Du Guijie , You Aiqing , Cheng Zhukuan 
Published: December 2022

Summary

The endonuclease methyl methanesulfonate and UV‐sensitive protein 81 (MUS81) has been reported to participate in DNA repair during mitosis and meiosis. However, the exact meiotic function of MUS81 in rice remains unclear.

Here, we use a combination of physiological, cytological, and genetic approaches to provide evidence that MUS81 functions in atypical recombination intermediate resolution rather than crossover designation in rice.

Cytological and genetic analysis revealed that the total chiasma numbers in mus81 mutants were indistinguishable from wild‐type. The numbers of HEI10 foci (the sites of interference‐sensitive crossovers) in mus81 were also similar to that of wild‐type. Moreover, disruption of MUS81 in msh5 or msh4 msh5 background did not further decrease chiasmata frequency, suggesting that rice MUS81 did not function in crossover designation. Mutation of FANCM and ZEP1 could enhance recombination frequency. Unexpectedly, chromosome fragments and bridges were frequently observed in mus81 zep1 and mus81 fancm, illustrating that MUS81 may resolve atypical recombination intermediates.

Taken together, our data suggest that MUS81 contributes little to crossover designation but plays a crucial role in the resolution of atypical meiotic intermediates by working together with other anti‐crossover factors.