bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUATION OF FAMILY FARMERS HEALTH WITH LONG TERM EXPOSURE TO PESTICIDES IN A BRAZILIAN NORTH EAST REGION: A CLINICAL EPIDEMIOLOGICAL STUDY
Authors: Zanaga Trapé Angelo 
Published: July 2022

O presente estudo analisou o estado clínico de 1.000 agricultores da Serra da Ibiapaba, no Noroeste do estado do Ceará, uma região rica em plantações de diferentes frutas e legumes, e assim obter dados sobre o perfil epidemiológico dos agricultores(as) da região, os agrotóxicos mais utilizados, uso de equipamentos de proteção individual, comorbidades mais prevalentes. Foram avaliados homens e mulheres com exposição de longo prazo e contato direto a agrotóxicos, por meio de avaliação clínica feita. Esta avaliou a condição epidemiológica, medida de pressão arterial, peso, altura e cálculo de Índice de Massa Corporal (IMC), além da aplicação do teste de Audit (Alcohol Use Disorder Identification Test) para alcoolismo. Dentre os principais resultados vale destacar que 17% dos entrevistados referiu utilizar o Equipamento de Proteção Individual (EPI) durante o trabalho de contato com agrotóxicos. Dentre os agrotóxicos mais utilizados e relacionados ao grau de toxicidade, 25 % altamente tóxicos e 41% medianamente tóxicos. Quanto ao uso de álcool e peso, verificou-se que 33% dos agricultores fazem uso indevido do mesmo. Com isso, não foi identificado, por meio das análises realizadas, nenhuma tendência de morbidade relacionada à exposição de longo prazo e contato direto aso agrotóxicos, porém, ficou atestado o uso equivocado dos EPIs pela maioria dos entrevistados.
Interaktivna vizualizacija gosto poseljenih volumnov
Authors: Lesar Žiga , Marolt Matija 
Published: July 2022

V clanku obravnavamo neposredno upodabljanje volumnov, ki vsebujejo številne podobne primerke struktur, kot so slike polikristalnih materialov, z vlakni ojacenih polimerov in znotrajceličnih struktur. V teh primerih je gostota primerkov tako velika, da obstojece metode za upodabljanje ne omogočajo dobrega vpogleda v notranjost volumnov zaradi kolicine zastiranja med primerki. Predstavljamo novo metodo za upravljanje vidnosti pri vizualizaciji tovrstnih podatkov, ki nam omogoca skrivanje posameznih primerkov, poudarjanje primerkov z dolocenimi lastnostmi, red ˇ cenje primerkov in zlivanje segmentacije s surovimi podatki. Metodo smo preizkusili na sliki z vlakni ojacenega polimera, kjer omogoča boljši pregled notranjosti volumna.
Digitalizacija in prilagoditev psihološkega testa za uporabo s sistemom za spremljanje očesnih gibov
Authors: Groznik Vida 
Published: July 2022

Demenca je najpogostejša nevrološka motnja, za katero po svetu boleha okoli 50 milijonov ljudi, ta številka pa se zaradi staranjaprebivalstva vztrajno vecˇa. Raziskave kažejo, da se znaki demence v obliki kognitivnega upada nakazujejo že nekaj let pred jasnoizraženo klinicˇno sliko. V primeru, da te znake odkrijemo v fazi blagega kognitivnega upada (MCI), lahko z razlicˇnimi pristopiupocˇasnimo ali celo zaustavimo napredovanje bolezni v demenco. Za postavitev diagnoze je trenutno potreben pregled prinevrologu in psihologu, ki
postavita diagnozo. Žal pa le redki bolniki pridejo do specialistov, ko so še v fazi MCI. Eden izmed testov, ki se ga psihologi pogostoposlužujejo, je test s Corsijevimi kockami. S pomocˇjo le-tega psiholog lahko oceni stopnjo okvare vidno-prostorskega delovnega spomina, ki med drugim lahko nakazuje na MCI. Test se ponavadi izvaja s fizicˇnimi kockami, razporejenimi na podlago. Psiholog vnakljucˇnem zaporedju tapka po kockah, naloga preizkušanca pa je, da za psihologom ponovi tapkanje v istem vrstnem redu. Eden izmed nacˇinov za pravocˇasno detekcijo MCI je digitalizacija in avtomatizacija nevropsihološkega testiranja z uporabo sodobnihtehnologij. V zadnjih letih so se mocˇno izboljšali sistemi za sledenje ocˇesnim gibom, zaradi njihove cenovne dostopnosti pa so postalizanimivo orodje za potrebe raziskovanja nevroloških bolezni, pogosto tudi za raziskovanje razlicˇnih stopenj kognitivnega upada. Vcˇlanku predlagamo prilagoditev in digitalizacijo testa Corsi za uporabo skupaj s sistemom za sledenje ocˇesnim gibom. Skupaj s šenekaterimi drugimi testi (npr. gladko sledenje tocˇki) bi tako predstavljal baterijo nalog za avtomatsko detekcijo znakov MCI z uporabosistema za sledenje ocˇesnim gibom. Tovrsten sistem bi lahko kot neke vrste presejalni test uporabljalo zdravstveno varstvo naprimarni ravni, ki bi ob odkritju prisotnosti MCI bolnika pravocˇasno napotil na pregled pri specialistu.
Pogovor sodelavcev ob 20-letnici Islovarja
Authors: Puc Katarina , Schlamberger Niko , Batagelj Vladimir , Turk Tomaž , Kanič Ivan 
Published: July 2022

Prispevek predstavlja dragocen kronološki zapis nastanka in razvoja Islovarja. V pogovoru so podana izhodišča, ki so pred 20 leti privedla do vzpostavitve interaktivnega slovarja za področje računalništva in informatike. Opisani so problemi z izrazoslovjem, na katere so naleteli načrtovalci tega pomembnega spletnega orodja. Razvoj slovarja je v bistvu sledil uvajanju računalništva in informatike v Sloveniji in hkrati doživljal tudi tehnološke spremembe. Iz prvih skromnih poskusov je prerasel v zrelega mladeniča.
Nagovor urednice
Authors: Kljajić Borštnar Mirjana 
Published: July 2022

Pred vami je druga redna številka revije Uporabna informatika, letnika 2022. S preteklo številko revije je svoje delo v vlogi glavnega urednika zaključil zaslužni prof. dr. Saša Divjak, ki je to nalogo odlično opravljal od leta 2017. Za dosedanje delo se mu najlepše zahvaljujemo in se veselimo njegovega nadaljnjega sodelovanja v vlogi člana uredniškega odbora revije.
S tokratno številko se predstavljam v vlogi glavne urednice dr. Mirjana Kljajić Borštnar, v vlogi tehničnega urednika pa me bo še naprej podpiral dr. Slavko Žitnik, docent s fakultete za računalništvo in informatiko.
Halaqas, relational subjects, and revolutionary committees in Syria
Authors: Al-Khalili Charlotte 
Published: July 2022

Abstract
Through an ethnographic account of Syrian halaqas (Sunni religious circles) from the 1980s until the 2011 Syrian revolution, this article argues that halaqas have a revolutionary potential. The analysis demonstrates that Syrian religious circles are spaces of self-transformation that have heterotopic qualities. The Darayya halaqa studied here is a space where present and future are collapsed: a space in which future revolutionary selves and societies are already enacted. This temporal collapse is thus simultaneously a scalar one, for through the emergence of a relational or unbounded subject, a revolutionary project is being performed. This project is, moreover, without a preexisting program that its members seek to implement in a distant future; it is rather a revolutionary project that is perpetually in the making through discussions and actions happening within it.
F*ck the Police!
Authors: Alves Jaime A. 
Published: July 2022

Abstract
On the morning of 6 May 2021, the military police invaded the favela of Jacarezinho, one of Rio de Janeiro's slums, and killed 28 people during a military operation tellingly named Operation Exceptis. Photos of dead bodies in the alleys of the favela and denouncements of extrajudicial executions of individuals who had already surrendered circulated widely on the internet. Jacarezinho adds to a troubling record of police killings that includes and goes far beyond the 1992 Massacre of Carandiru, when 111 prisoners were slaughtered by São Paulo's police during a prison riot, and the equally infamous 2006 Crimes of May, when at least six hundred civilians were killed within the span of one week (Mães de Maio 2019). While human rights organizations denounced the Jacarezinho massacre for what it was, the police argued that “the only execution that took place was that of the police, unfortunately. The other deaths that happened were those of traffickers who attacked the lives of policemen and were neutralized” (Betim 2021). On a social media network, President Jair Bolsonaro praised “all the warriors who risk their lives in the daily mission to protect the good people,” and lamented that instead of honoring the life of the officer killed during the operation, human rights activists were treating “criminals who steal, kill, and destroy families” (Veja 2021) as innocent victims.
Źródła finansowania działalności gospodarczej kobiet z obszarów wiejskich na przykładzie województwa podlaskiego
Authors: Szepelska Alina 
Published: July 2022

Podmioty gospodarcze niezależnie od wielkości i miejsca prowadzenia działalności potrzebują finansowania. Biorąc pod uwagę fakt, że sektor MŚP ma znaczący udział w tworzeniu PKB, problem finansowania przedsiębiorstw zasługuje na uwagę. Przedsiębiorstwa małe i średnie generują co drugą złotówkę – 47,3% PKB, w tym najmniejsze firmy blisko co trzecią – 29,4% [Raport PARP 2013:13]. Mimo to małe i średnie firmy mają trudności w pozyskiwaniu kapitału, a swoją działalność finansują często ze środków własnych. Z badań Eurobarometru wynika, że przedsiębiorstwa kobiece dostają pożyczki na mniejsze kwoty i na wyższy procent, częściej też niż mężczyźni finansują swoją działalność ze środków własnych: 80% przedsiębiorstw prowadzonych przez kobiety i 65% przedsiębiorstw prowadzonych przez mężczyzn [Survey of the Observatory of European SMEs 2007]. Celem niniejszego artykułu jest analiza źródeł finansowania działalności gospodarczej małych i średnich przedsiębiorców, w tym prowadzonych przez kobiety, głównie z obszarów wiejskich województwa podlaskiego. Analizy dokonano na podstawie literatury przedmiotu oraz wybranych wyników badań pt. „Przedsiębiorczość kobiet na obszarach wiejskich na przykładzie województwa podlaskiego”, przeprowadzonych w ramach pracy badawczej BDS-7/IP/10/2013 w drugiej połowie 2014 r. (fragment tekstu)
ARAHAN RENCANA PENGEMBANGAN KOMODITAS UNGGULAN DI KABUPATEN SUMENEP WILAYAH DARATAN, PROVINSI JAWA TIMUR
Authors: Zainal Arifin, Santun R.P Sitorus, & Janthy T. Hidayat Zubhan 
Published: July 2022

Kabupaten Sumenep Wilayah Daratan, Provinsi Jawa Timur didominasi oleh sektor pertanian. Sektor pertanian merupakan mata pencaharian utama dari masyarakat Kabupaten Sumenep Wilayah Daratan dan juga merupakan kontributor terbesar untuk Produk Regional Domestik Bruto (PDRB) yaitu 39,41% pada tahun 2017. Penelitian ini dilakukan untuk merumuskan arahan rencana pengembangan komoditas unggulan di Kabupaten Sumenep Wilayah Daratan dengan mengidentifikasi komoditas unggulan pertanian, menganalisis potensi lahan yang akan dikembangkan dan juga hirarki wilayah. Data diperoleh dari instansi terkait serta melalui observasi langsung dan wawancara dengan para narasumber ahli. Beberapa metode digunakan untuk memproses data, LQ dan DS, analisis ketersediaan dan kesesuaian lahan, dan skallogram. LQ dan DS digunakan sebagai metodologi untuk menganalisis komoditas unggulan. Identifikasi lahan potensial dilakukan dengan melakukan analisis ketersediaan dan kesesuaian lahan, sedangkan hirarki wilayah dengan menggunakan metode skalogram. Hasil penelitian menunjukkan bahwa arahan pengembangan komoditas unggulan prioritas pertama dengan hirarki wilayah tertinggi dan memiliki lahan berpotensi pengembangan di Kabupaten Sumenep Wilayah Daratan adalah Jambu Mente di Kecamatan Batuan, Jagung di Kecamatan Dungkek, dan Kacang Hijau pada Kecamatan Kota Sumenep. Kata Kunci: arahan dan strategi pengembangan, kesesuaian lahan, komoditas unggulan.
STRATEGI PENINGKATAN JUMLAH WISATAWAN GEOPARK CILETUH – PELABUHAN RATU : SEBAGAI DAMPAK PENGARUH PEMBANGUNAN TOL BOCIMI
Authors: RAMDIANSYAH HARI , DJAKAPERMANA RUCHYAT DENI , ARTININGSIH TITIK PENTA 
Published: July 2022

Kabupaten Sukabumi memiliki potensi pariwisata yang besar, khususnya kawasan Geopark Ciletuh-Palabuhanratu yang merupakan bagian dari UNESCO Global Geopark sejak tahun 2018. Pembangunan Tol Bocimi, diharapkan dapat meningkatkan aksesibilitas antara Perkotaan Jabodetabek sebagai pangsa pasar wisatawan dengan Geopark Ciletuh – Palabuhanratu sebagai destinasi wisata. Tujuan dari penelitian ini adalah (1) Menganalisis interaksi Jabodetabek dengan Kabupaten Sukabumi, (2) Menganalisis pengaruh pembangunan Tol Bocimi terhadap jumlah wisatawan, (3) Melakukan kajian pemilihan moda transportasi, dan (4) Merumuskan strategi untuk meningkatkan jumlah wisatawan. Penelitian dilakukan dengan menggunakan mix method analysis dengan memanfaatkan data hasil survei sekunder dan penyebaran kuesioner kepada wisatawan. Hasil penelitian menunjukkan bahwa pembangunan Tol Bocimi mampu meningkatkan nilai interaksi antara wilayah, namun tidak memiliki pengaruh terhadap jumlah wisatawan yang selalu meningkat setiap tahunnya. Hasil pengolahan data kuesioner menunjukkan bahwa adanya potensi untuk pengembangan transportasi umum yang nyaman dan cepat menuju tujuan wisata dan dengan target utama Generasi Z. Strategi prioritas dalam penelitian ini adalah: (i) Menyiapkan sarana transportasi untuk wisatawan Generasi Z yang aman dan nyaman, (ii) Menyediakan akomodasi yang beragam untuk mengakomodasi berbagai kelas/golongan, (iii) Mengadakan event unik yang berpotensi masuk dalam Calendar of Events (CoE) Kementerian Pariwisata, dan (iv) Memanfaatkan budaya lokal untuk menarik wisatawan. Kata kunci : Infrastruktur, Interaksi Wilayah, Pariwisata, Strategi
POTENSI PENGEMBANGAN ENERGI BARU TERBARUKAN DALAM MENDUKUNG PERTUMBUHAN KAWASAN PERBATASAN DI KABUPATEN NUNUKAN
Authors: MIRANTI, JUNAIDY BURHAN, dan MOCHAMAD YUNUS SRI 
Published: July 2022

Kabupaten Nunukan yang terletak di Provinsi Kalimantan Utara merupakan salah satu Daerah Perbatasan dengan rasio elektrifikasi terendah. Kabupaten Nunukan memiliki potensi alam yang dapat dikelola sebagai sumber energi listrik untuk memenuhi kebutuhan listrik. Potensi ini dapat dimanfaatkan sebagai sumber listrik dari angin, air dan matahari. Kajian ini bertujuan untuk membebankan potensi energi baru dan terbarukan (EBT) yang dapat dikembangkan dan menganalisis kelayakan investasi pada potensi energi baru terbarukan (EBT), yang dapat menentukan arah pengembangan energi baru dan terbarukan di kabupaten nun. Dalam menentukan potensi energi baru terbarukan menggunakan program LEAP. NVP, IRR, B/C rasio dan Payback Period untuk mengetahui estimasi investasi potensi ebt. Berdasarkan analisis, energi angin tidak dapat dikembangkan. Air dan energi surya layak untuk dikembangkan di kabupaten nunukan. Energi air memiliki potensi sebesar 246,67 KWH dengan NPV sebesar Rp. 1.009.874.801 dan modal awal bisa kembali di tahun ke-9. Energi surya memiliki potensi sebesar 1.775,3 KWH, nilai NPV sebesar Rp 77.579.01.054 dan modal awal dapat dipulihkan pada tahun ke-3. Potensi pengembangan Energi Baru dan Terbarukan merupakan investasi jangka panjang dan dapat dijadikan sebagai sektor yang memberikan kontribusi pendapatan daerah yang besar dengan memanfaatkan bahan baku yang banyak tersedia di Kabupaten Nunukan dan ramah lingkungan. Kata kunci : Energi Terbarukan, Kelayakan, Investasi, Potensi.
Neutrophil and Eosinophil Responses Remain Abnormal for Several Months in Primary Care Patients With COVID-19 Disease
Authors: Jukema B. N. , Smit K. , Hopman M. T. E. , Bongers C. C. W. G. , Pelgrim T. C. , Rijk M. H. , Platteel T. N. , Venekamp R. P. , Zwart D. L. M. , Rutten F. H. , Koenderman L. 
Published: July 2022

IntroductionNeutrophil and eosinophil activation and its relation to disease severity has been understudied in primary care patients with COVID-19. In this study, we investigated whether the neutrophil and eosinophil compartment were affected in primary care patients with COVID-19.MethodsCOVID-19 patients, aged ≥ 40 years with cardiovascular comorbidity presenting to the general practitioner with substantial symptoms, partaking in the COVIDSat@Home study between January and April 2021, were included. Blood was drawn during and 3 to 6 months after active COVID-19 disease and analyzed by automated flow cytometry, before and after stimulation with a formyl-peptide (fNLF). Mature neutrophil and eosinophil markers at both time points were compared to healthy controls. A questionnaire was conducted on disease symptoms during and 3 to 6 months after COVID-19 disease.ResultsThe blood of 18 COVID-19 patients and 34 healthy controls was analyzed. During active COVID-19 disease, neutrophils showed reduced CD10 (p= 0.0360), increased CD11b (p= 0.0002) and decreased CD62L expression (p&lt; 0.0001) compared to healthy controls. During active COVID-19 disease, fNLF stimulated neutrophils showed decreased CD10 levels (p&lt; 0.0001). Three to six months after COVID-19 disease, unstimulated neutrophils showed lowered CD62L expression (p= 0.0003) and stimulated neutrophils had decreased CD10 expression (p= 0.0483) compared to healthy controls. Both (un)stimulated CD10 levels increased 3 to 6 months after active disease (p= 0.0120 andp&lt; 0.0001, respectively) compared to during active disease. Eosinophil blood counts were reduced during active COVID-19 disease and increased 3 to 6 months after infection (p&lt; 0.0001). During active COVID-19, eosinophils showed increased unstimulated CD11b (p= 0.0139) and decreased (un)stimulated CD62L expression (p= 0.0036 andp= 0.0156, respectively) compared to healthy controls. Three to six months after COVID-19 disease, (un)stimulated eosinophil CD62L expression was decreased (p= 0.0148 andp= 0.0063, respectively) and the percentage of CD11bbrightcells was increased (p= 0.0083 andp= 0.0307, respectively) compared to healthy controls.ConclusionAutomated flow cytometry analysis reveals specific mature neutrophil and eosinophil activation patterns in primary care patients with COVID-19 disease, during and 3 to 6 months after active disease. This suggests that the neutrophil and eosinophil compartment are long-term affected by COVID-19 in primary care patients. This indicates that these compartments may be involved in the pathogenesis of long COVID.
Prognostic performance of multiple biomarkers in patients with acute coronary syndrome without standard cardiovascular risk factors
Authors: Wang Le , Cong Hong-liang , Zhang Jing-xia , Li Xi-ming , Hu Yue-cheng , Wang Chen , Lang Jia-chun , Zhou Bing-yang , Li Ting-ting , Liu Chun-wei , Yang Hua , Ren Li-bin , Qi Wei , Li Wen-yu 
Published: July 2022

Background and aimsAcute coronary syndrome (ACS) without standard modifiable cardiovascular risk factors (SMuRFs) represents a special case of ACS. Multiple biomarkers have been shown to improve risk stratification in patients with ACS. However, the utility of biomarkers for prognostic stratification in patients with ACS without SMuRFs remains uncertain. The aim of the present study was to evaluate the prognostic value of various biomarkers in patents with ACS without SMuRFs.MethodsData of consecutive patients with ACS without SMuRFs who underwent coronary angiography in Tianjin Chest Hospital between January 2014 and December 2017 were retrospectively collected. The primary outcome was the occurrence of major adverse cardiovascular event (MACE), defined as a composite of cardiovascular death, myocardial infarction and stroke. Seven candidate biomarkers analyses were analyzed using models adjusted for established risk factors.ResultsDuring a median 5-year follow-up, 81 of the 621 patients experienced a MACE. After adjustment for important covariates, elevated fibrinogen, D-dimer, N-terminal proB-type natriuretic peptide (NT-proBNP), and lipoprotein (a) [Lp(a)] were found to be individually associated with MACE. However, only D-dimer, NT-proBNP and Lp(a) significantly improved risk reclassification for MACE (all P &lt; 0.05). The multimarker analysis showed that there was a clear increase in the risk of MACE with an increasing number of elevated biomarkers and a higher multimarker score. The adjusted hazard ratio- for MACE (95% confidential intervals) for patients with 4 elevated biomarkers was 6.008 (1.9650–18.367) relative to those without any elevated biomarker-. Adding- the 4 biomarkers or the multimarker score to the basic model significantly improved the C-statistic value, the net reclassification index and the integrated discrimination index (all P &lt; 0.05).ConclusionFibrinogen, D-dimer, NT-proBNP and Lp(a) provided valuable prognostic information for MACE when applied to patients with ACS without SMuRFs. The multimarker strategy, which combined multiple biomarkers reflecting different pathophysiological process with traditional risk factors improved the cardiovascular risk stratification.
Adrenalectomies in children and adolescents in Germany – a diagnose related groups based analysis from 2009-2017
Authors: Uttinger Konstantin L. , Riedmeier Maria , Reibetanz Joachim , Meyer Thomas , Germer Christoph Thomas , Fassnacht Martin , Wiegering Armin , Wiegering Verena 
Published: July 2022

BackgroundAdrenalectomies are rare procedures especially in childhood. So far, no large cohort study on this topic has been published with data on to age distribution, operative procedures, hospital volume and operative outcome.MethodsThis is a retrospective analysis of anonymized nationwide hospital billing data (DRG data, 2009-2017). All adrenal surgeries (defined by OPS codes) of patients between the age 0 and 21 years in Germany were included.ResultsA total of 523 patient records were identified. The mean age was 8.6 ± 7.7 years and 262 patients were female (50.1%). The majority of patients were between 0 and 5 years old (52% overall), while 11.1% were between 6 and 11 and 38.8% older than 12 years. The most common diagnoses were malignant neoplasms of the adrenal gland (56%, mostly neuroblastoma) with the majority being younger than 5 years. Benign neoplasms in the adrenal gland (D350) account for 29% of all cases with the majority of affected patients being 12 years or older. 15% were not defined regarding tumor behavior. Overall complication rate was 27% with a clear higher complication rate in resection for malignant neoplasia of the adrenal gland. Bleeding occurrence and transfusions are the main complications, followed by the necessary of relaparotomy. There was an uneven patient distribution between hospital tertiles (low volume, medium and high volume tertile). While 164 patients received surgery in 85 different “low volume” hospitals (0.2 cases per hospital per year), 205 patients received surgery in 8 different “high volume” hospitals (2.8 cases per hospital per year; p&lt;0.001). Patients in high volume centers were significant younger, had more extended resections and more often malignant neoplasia. In multivariable analysis younger age, extended resections and open procedures were independent predictors for occurrence of postoperative complications.ConclusionOverall complication rate of adrenalectomies in the pediatric population in Germany is low, demonstrating good therapeutic quality. Our analysis revealed a very uneven distribution of patient volume among hospitals.