bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis tingkat pengangguran terbuka di Indonesia periode sebelum dan saat pandemi covid-19
Authors: Mifrahi Mustika Noor , Darmawan Angga Setyo 
Published: August 2022

Abstract
Purpose – This study aims to analyze the Open Unemployment Rate (TPT) in Indonesia during and before the Covid-19 pandemic in terms of HDI, GRDP, minimum wage, and inflation.
Methods – The analytical method used is a paired sample test analysis and panel data analysis for each province in Indonesia from 2010 to 2021.
Findings – The results indicate that there were differences in the value of TPT in Indonesia in the period before and during the Covid-19 pandemic. In addition, the factors that affect the TPT rate in the period 2010-2021 are the growth rate of GRDP, HDI and Covid 19. While the value of the UMP level and inflation have no significant effect on TPT.
Implication – The results of the study recommend that policy makers in dealing with open unemployment in Indonesia focus more on microeconomic factors.
Originality – This research contributes to analyzing the open unemployment rate in Indonesia before and after covid-19

Abstrak
Tujuan – Penelitian ini bertujuan untuk menganalisis Tingkat Pengangguran Terbuka (TPT) di Indonesia pada saat dan sebelum adanya pandemi Covid-19 dari sisi IPM, PDRB, UMP, dan inflasi.
Metode – Metode analisis yang digunakan adalah analisis uji beda dan pengujian data panel untuk setiap provinsi di Indonesia dari tahun 2010 hingga 2021.
Temuan – Hasil penelitian menunjukkan bahwa terdapat perbedaan nilai TPT di Indonesia pada periode sebelum dan saat pandemi Covid-19. Selai itu, faktor yang mempengaruhi nilai TPT dalam periode 2010-2021 yaitu laju pertumbuhan PDRB, IPM dan Covid 19. Sedangkan nilai tingkat UMP dan inflasi tidak berpengaruh signifikan pada TPT.
Implikasi – Hasil penelitian merekomendasikan pada pengambil kebijakan dalam menangani penggangguran terbuka di Indonesia lebih menitik beratkan pada faktor-faktor mikroekonomi.
Orisinalitas – Penelitian ini berkontribusi dalam menganalisis tingkat pengangguran terbuka di Indonesia sebelum dan sesudah covid-19
Analisis determinan pertumbuhan ekonomi Provinsi Jawa Tengah
Authors: Rudatin Ari , Indraswari Enggarsani Maulida 
Published: August 2022

Abstract
Objectives – This study aims to analyze the effect of regional spending, number of tourist visits, and population on economic growth.
Methods – This study uses a multiple linear regression model with panel data from 2015-2020 in six districts/cities in the Kedu Residency Region.
Findings – The research results show that regional spending has a positive effect on economic growth, and the number of tourist visits positively affects economic growth. The population has no impact on economic growth.
Implications – Analysis of factors that can increase regional economic growth is essential for local governments to boost economic growth. Local governments should know which sectors should be developed more quickly to increase economic growth.
Originality – This study analyzes the effect of regional spending, number of tourist visits, and population on economic growth.

Abstrak
Tujuan – Penelitian ini bertujuan menganalisis pengaruh belanja daerah, jumlah kunjungan wisata, dan jumlah penduduk terhadap pertumbuhan ekonomi.
Metode – Penelitian ini menggunakan model regresi linear berganda dengan data panel yang diambil dari tahun 2015-2020 di enam kabupaten/kota di Wilayah Karesidenan Kedu.
Temuan – Hasil dari penelitian yang telah dilakukan menunjukkan bahwa belanja daerah berpengaruh positif terhadap pertumbuhan ekonomi, jumlah kunjungan wisata berpengaruh positif terhadap pertumbuhan ekonomi dan jumlah penduduk tidak berpengaruh terhadap pertumbuhan ekonomi.
Implikasi – Analisis faktor-faktor yang dapat meningkatkan pertumbuhan ekonomi daerah penting dilakukan sebagai acuan pemerintah daerah dalam meningkatkan pertumbuhan ekonomi. Pemerintah daerah sebaiknya mengetahui sektor mana saja yang harus dikembangkan lebih cepat dalam meningkatkan pertumbuhan ekonomi.
Originalitas – Penelitian ini focus untuk menganalisis pengaruh belanja daerah, jumlah kunjungan wisata, dan jumlah penduduk terhadap pertumbuhan ekonomi.
Perioperative Identification and Management of Hyperglycemia in Orthopaedic Surgery
Authors: Lamanna Daniel L. , McDonnell Marie E. , Chen Antonia F. , Gallagher John M. 
Published: August 2022

➤ The consequences of undermanaged perioperative hyperglycemia are notable and can have a serious impact on adverse postoperative outcomes, especially surgical site infections and periprosthetic joint infections (PJIs).➤ Preoperative screening of hemoglobin A1c with a goal threshold of <7.45% is ideal.➤ There are a variety of risk factors that contribute to hyperglycemia that should be considered in the perioperative period, including glucocorticoid use, nutritional factors, patient-specific factors, anesthesia, and surgery.➤ There are expected trends in the rise, peak, and fall of postoperative blood glucose levels, and identifying and treating hyperglycemia as swiftly as possible are the fundamental aims of treatment and improved glucose control. Performing frequent postoperative blood glucose monitoring (in the post-anesthesia care unit, on the day of surgery at 1700 and 2100 hours, and in the morning of postoperative day 1) should be considered to allow for the early detection of alterations in glucose metabolism. In addition, instituting a postoperative dietary restriction of carbohydrates should be considered.➤ The use of insulin as a hypoglycemic agent in orthopaedic patients is relatively safe and is an effective means of controlling fluctuating blood glucose levels. Insulin therapy should be administered to treat hyperglycemia at ≥140 mg/dL when fasting and ≥180 mg/dL postprandially. Insulin therapy should be ceased at blood glucose levels of <110 mg/dL; however, monitoring for glycemic dysregulation should be continued. In all cases of complex diabetes, consultation with diabetes specialty services should be considered.➤ The emerging use of technology, including continuous subcutaneous insulin pump therapy and continuous glucose monitoring, is an exciting area of further research and development as such technology can more immediately detect and correct aberrations in blood glucose levels.
Investigation of Rock Burst Mechanism under Thermomechanical Coupling Conditions Based on Rock Mechanical Tests
Authors: Li Tianbin , Shu Zhile , Zhang Xin , Gao Meiben , Pan Huangsong 
Published: August 2022

Abstract
The thermomechanical (TM) coupling effects of rock bursts have attracted considerable attention from researchers owing to the high geothermal and geostresses in deep tunnels in regions such as Western China. To study the brittleness and rock burst mechanism under TM conditions, various tests, such as splitting, uniaxial compression, rock burst tendency, and rock burst physical model tests, were conducted at temperatures ranging from 20°C to 80°C. The results revealed that, when granite samples were heated, their tensile strengths decreased in the splitting tests. Their peak stresses and the corresponding strains increased; their macroscopic tensile fracture surfaces became more evident; and the microcosmic tensile properties of intergranular fractures became prominent under uniaxial compression. Rock burst physical model tests and acoustic emission monitoring results revealed that, at higher temperatures, the fracture degree and failure range were larger, the energy was higher and more concentrated during failure, and failure occurred earlier. The brittleness index B, rock burst tendency Wet, and σθ/σc all exhibited a clear increasing tendency with an increase in temperature. The rock burst mechanism, considering the temperature effect, can be summarized as follows: the increase in brittle tensile fracture components and geostress caused by temperature increasing is conducive to the rapid release of energy, which will promote the occurrence of rock burst. The researching result is of great academic value and practical significance for the prevention, design, and safe construction of rock burst in deep high geothermal tunnels.
ConsensusPrime - a bioinformatic pipeline for alignment filtering and ideal consensus primer design
Authors: Collatz Maximilian , Braun Sascha D. , Monecke Stefan , Ehricht Ralf 
Published: August 2022

Abstract
High quality oligonucleotides for molecular amplification and detection procedures of diverse target sequences depend on sequence homology. The processing of input sequences and the identification of homogeneous regions in alignments can be done manually only if alignments are small and if they contain sequences of high similarity. For large and inhomogeneous alignments, the process of finding the best regions needs to be automated.The ConsensusPrime pipeline was developed sort out redundant and technical interfering data in multiple sequence alignments and detect the most homolog regions from multiple sequences. It automates the prediction of optimal consensus primers for molecular analytical and sequence-based procedures/assays.ConsensusPrime is a fast and easy to use pipeline for predicting optimal consensus primers that is executable on local systems without depending on external resources and webservices. An implementation in a Docker image ensures platform-independent executability and installability despite the combination of multiple programs. The source code and installation instructions are publicly available on GitHub (https://github.com/mcollatz/ConsensusPrime).
Evaluating the harmonisation potential of diverse cohort datasets
Authors: Bauermeister Sarah , Phatak Mukta , Sparks Kelly , Sargent Lana , Grizwold Michael , McHugh Caitlin , Nalls Mike , Young Simon , Bauermeister Joshua , Elliot Paul , Steptoe Andrew , Porteous David , Dufouil Carole , Gallacher John 
Published: August 2022

Abstract

Background
Data discovery, the ability to find datasets relevant to an analysis, increases scientific opportunity, improves rigour and accelerates activity. Rapid growth in the depth, breadth, quantity and availability of data provides unprecedented opportunities and challenges for data discovery. A potential tool for increasing the efficiency of data discovery, particularly across multiple datasets is data harmonisation.
Methods
A set of 124 variables, identified as being of broad interest to neurodegeneration, were harmonised using the C-Surv data model. Harmonisation strategies used were simple calibration, algorithmic transformation and standardisation to the Z-distribution. Widely used data conventions, optimised for inclusiveness rather than aetiological precision, were used as harmonisation rules. The harmonisation scheme was applied to data from four diverse population cohorts.
Results
Of the 120 variables that were found in the datasets, correspondence between the harmonised data schema and cohort-specific data models was complete or close for 111 (93%). For the remainder, harmonisation was possible with a marginal a loss of granularity.
Conclusions
Although harmonisation is not an exact science, sufficient comparability across datasets was achieved to enable data discovery with relatively little loss of informativeness. This provides a basis for further work extending harmonisation to a larger variable list, applying the harmonisation to further datasets, and incentivising the development of data discovery tools.
Association of Clinical, Laboratory and Ultrasound Characteristics With the Etiology of Peripheral Lymphadenopathy in Children
Authors: Berce Vojko , Brodnik Aleksandra Zorko , Dorič Maja , Rataj Nina , Kolarič Tjaša 
Published: August 2022

Abstract
Background: Peripheral lymphadenopathy affects most children at least once in a lifetime and represents a major reason for concern for children and their caregivers, although the malignancy is an uncommon cause of lymphadenopathy in this age group. Viral infections such as infectious mononucleosis is a common cause of bilateral cervical lymphadenitis or generalized lymphadenopathy in older children. Pyogenic bacteria and granulomatous diseases usually cause unilateral lymph node enlargement. We aimed to identify the most common causes of peripheral lymphadenopathy in hospitalized children and to determine the clinical, laboratory and ultrasound characteristics that enable easy and accurate etiological diagnosis.Methods: We performed a cross-sectional study including 139 children who were hospitalized because of peripheral lymphadenopathy and in whom the etiological diagnosis could be ascertained. Blood tests, including serology for Epstein-Barr virus and Bartonella hensleae were performed in all children, and ultrasound of lymph nodes was performed in 113 (81.3%) of them. Incision with the detection of bacteria, aspiration biopsy or extirpation of lymph nodes were performed when clinically indicated. The Mann-Whiney U test or chi-squared test and a (multinomial) regression analysis was performed to compare epidemiological, clinical, laboratory and ultrasound characteristics of patients with three most common etiologies.Results: Lymphadenopathy was generalized in 9 (6.5%) patients. 114 (82.0%), 6 (4.6%), 6 (4.6%) and 4 (3.1%) patients presented with localized lymphadenopathy in the cervical, axillary, supraclavicular and inguinofemoral areas, respectively. Malignant etiology was established in only 3 (2.2%) patients. Bacterial lymphadenitis, infectious mononucleosis (IM) and cat scratch disease (CSD) was diagnosed in 66 (47.5%), 31 (22.3%) and 29 (20.9%) patients, respectively. Bacterial lymphadenitis was significantly associated with neutrophilia (p<0.01) and increased C-reactive protein levels (p<0.01). IM was associated with pharyngitis (p<0.01), leukocytosis without neutrophilia (p=0.03), increased blood liver enzyme levels (p<0.01) and lactate dehydrogenase levels (p<0.01). CSD was associated with recent contact with a cat (p<0.01), absence of a fever (p<0.01) and normal white blood cell count (p<0.01).Conclusions: Thorough history and clinical examination in combination with a few basic laboratory tests enable fast and accurate differentiation between the most common etiologies of lymphadenopathy in children to avoid unnecessary procedures and hospitalizations.
Persistent symmetrical bilateral hypertension on DWI in a patient with Hashimoto's thyroiditis: a Case Report
Authors: Zhu Shu-lai , Pan Xin-xin , Peng Yu-hua 
Published: August 2022

Abstract
We report a case diagnosed metabolic encephalopathy following Hashimoto's thyroiditis whose MRI shown persistent symmetrical bilateral hypertension on DWI in the past two years. To our knowledge this is the first report of persistent symmetrical bilateral hypertension on DWI in a patient with Hashimoto's thyroiditis.
Comparison of weight-bearing full-length radiography and three-dimensional computed tomography scan-based models for the assessment of knee joint coronal alignment following total knee arthroplasty
Authors: Kato Michitaka , Warashina Hideki , Kataoka Akito , Mitamura Shingo 
Published: August 2022

Abstract
Purpose: We evaluated measurement reliability and validity of long-leg radiography (LLR) after total knee arthroplasty (TKA) by comparing postoperative three-dimensional computed tomography (3DCT) scans of the lower extremities.Methods: We retrospectively collected data from 55 knees that underwent postoperative 3DCT, 5-day and 6-month LLR for coronal alignment after TKA. Coronal femoral component angle (CFA) and coronal tibial component angle (CTA) were measured with postoperative 3DCT, 5-day and 6-month LLR. The correlations between the hip–knee–ankle angle (HKAA), CFA, and CTA measured using 3DCT scans and radiographs (5-day and 6-month LLR) were analysed using Pearson’s correlation coefficient (PCC). Bland-Altman plots were constructed to assess agreement between 5-day and 6-month LLR and3DCT scan measurements.Results: The mean difference in the HKAA between 3DCT and 5-day and 6-month LLR was 1.3°±1° and 1.1°±0.7°, respectively. Differences of >1° in the HKAA between 3DCT and LLR were observed in 31 (56.4%) and 28 (50.9%) knees during 5-day and 6-month LLR, respectively. Differences of >2° in these parameters were observed in 15 (27.3%) and 9 (16.4%) knees during 5-day and 6-month LLR, respectively. However, 3DCT scan and LLR measurements showed a strong correlation (PCC, 0.81–0.92; P < 0.000) for all HKAA, CFA, and CTA, and the validity of the Bland-Altman plot was within acceptable limits.Conclusion: Coronal alignment measurement using LLR yielded good reliability and validity. However more than half of the HKA angle values measured by 3DCT scan and radiographs differed by more than 1°, and approximately 20% differed by more than 2°.Level of Evidence: Level IV
Exploring Deaf/Hard of Hearing students reading strategies utilization
Authors: Hailemariam Bereket , Barkesa Mendida 
Published: August 2022

Abstract
The general objective of this study was to assess reading comprehension strategies utilization of deaf students of Mekane Eyesus School for the Deaf. Accordingly, it assessed reading comprehension strategies use of each of grades 5–12 deaf students and determined the overall reading comprehension strategies use of the participant deaf students. A case study research design was chosen. Twenty one grade 5–12 deaf students were selected randomly for the study. The data were collected through Cognitive Awareness of Reading Strategies Inventory (CARSI; Mokhtari & Reichard, 2002). The data from the questionnaire were analyzed using descriptive statistics in SPSS Version 21. The results revealed that medium level global reading strategies subscale use mean (M = 3.26, SD = .69) with the majority of the sample 10 (47.6%) reporting medium level use of Global Strategies use. On the other hand, problem-solving strategies use subscale mean was (M = 3.67, SD = .69) with the majority of the sample 15 (71.4%), reported high level use of Problem solving strategies and Support strategies use subscale mean was (M = 3.6, SD = .81), with more than half of the sample, 13 (61.9%), reported high level use of Support strategies use. However, the Overall strategies use mean was (M = 3.47, SD = .61), with the majority of the sample 11 (52.4%), reported medium level use. As a result, the problem solving reading approach appeared to be used more frequently than the other strategy types in this study and the Overall strategies use revealed medium level use.
Induction TPF followed by concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locally advanced hypopharyngeal cancer: a preliminary result of a randomized phase 2 trial
Authors: Luo Xi , Huang Xiaodong , Liu Shaoyan , Wang Xiaolei , He Xiaohui , Luo Dehong , Luo Jingwei , Xiao Jianping , Wang Kai , Qu Yuan , Chen Xuesong , Zhang Ye , Wu Runye , Wang Jingbo , Zhang Jianghu , Xu Guozhen , Gao Li , Yi Junlin 
Published: August 2022

Abstract
Purpose
Concurrent chemoradiotherapy (CCRT) was one of the standard treatment choices for locally advanced hypopharyngeal carcinoma. The aim of this study was to investigate whether IC followed by CCRT is superior to CCRT in locally advanced hypopharyngeal carcinoma.
Methods and Materials:
142 patients were randomized to receive two cycles of docetaxal /cisplatin/5-fluorouracil (TPF) IC followed by CCRT or CCRT alone. The primary end point was overall survival (OS). Secondary end points included larynx-preservation rate, progression-free survival (PFS), distant metastasis-free survival (DMFS) and toxicities.
Results
113 of 142 patients were finally analyzed. With a median follow-up of 45.6 months (IQR 26.8–57.8), the 3-year OS was 53.1% in the IC + CCRT compared with 54.8% in the CCRT (HR, 1.004; 95% CI, 0.573 to 1.761; P = 0.988). There were no statistically significant differences in PFS, DMFS and larynx-preservation rate between the two groups. Grade 3–4 hematological toxicity incidence was much higher in the IC + CCRT group than that in the CCRT group (54.7% vs 10%, P < 0.001).
Conclusions
Adding induction TPF to CCRT could not improve the survival and larynx-preservation rate in locally advanced hypopharyngeal cancer but in the cost of higher acute hematological toxicities.
Vascular Characteristics and Prognosis of Gestational Trophoblastic Neoplasia with Uterine Arteriovenous Malformation
Authors: Zhou Qing , Liu Yuantao , Lu Xin , Zhang He , Ma Fenghua , Zhang Guofu 
Published: August 2022

Abstract
Objective: To investigate vascular characteristics and prognosis of gestational trophoblastic neoplasia (GTN) with uterine arteriovenous malformation(UAVM) Methods: Forty-four patients with GTN at our hospital from December 2015 to December 2020 were selected. Imaging characteristics of MRI and CE-MRA before treatment, treatment methods, and the prognosis were followed-up. Results: A total of 44 cases were included, including five cases of placental site trophoblastic tumor (PSTT) and 39 cases of the other GTN. There were two cases of PSTT combined with UAVM and 23 cases of the other GTN combined with UAVM. Thirty-nine cases of the other GTN were divided into two groups according to the presence or absence of UAVM. Data regarding the β-human chorionic gonadotropin value (<10,000 mIU/mL and ≥10,000 mIU/mL) were evaluated using Chi-square test (P = 0.001); the difference was statistically significant (P < 0.05). The average FIGO scores of the two groups were 4.19 (±3.69) and 6. 70 (±3.39) (P = 0.035); the difference was statistically significant (P < 0.05). Vascular characteristics of all the patients were analyzed.Conclusion: Most of the lesions are supplied by uterine arteries and drained by uterine veins and ovarian veins. When β-hCG is ≥10,000 mIU/mL, the probability of UAVM increased. The higher the prognosis score, the greater the possibility of UAVM.
Cytotoxic assessment of 3D printed photoinitiated prosthodontic resins versus heat polymerized acrylic resin (In-Vitro Study)
Authors: Farid Maisa , Mohamed Faten , Mehanna Radwa , Abd-ELLAH Mervat , Abdelrahman Hams 
Published: August 2022

Abstract
Background: Although 3D printed photoinitiated resins are among the many materials utilized in prosthetic appliances today, biocompatibility for photocuring 3D printing materials for direct and long-term contacting with living body remain scarce. The purpose of this in vitro study was to evaluate the cell viability of human gingival fibroblasts after the exposure to two different 3D printed photoinitiated resins and compare it to the traditionally used heat polymerized acrylic resin for up to 7 days.Methods: This comparative in vitro study of sample size (n= 96), where the 3D printed resin disc samples (n= 64), were divided into two test groups, test group 1 (TG1) for NextDent Base resin (n= 32) and test group 2 (TG2) for Dental LT clear resin (n= 32), to be compared to Heat polymerized acrylic resin samples (Reference group (RG)) (n= 32). Human gingival fibroblasts were extracted from attached keratinized gingival tissues collected from healthy patient undergoing clinical crown lengthening procedure, cellular viability using MTT assay in response to TG1, TG2 and RG samples was assessed throughout four-time intervals (24, 48, 72 and 168 hours). The One-Way ANOVA test followed by Tukey’s post hoc test and Repeated Measures ANOVA test were used for statistical analyses, statistically significant different at P value ≤ 0.05Results: Throughout time intervals, there was a decrease in cell viability of all groups but with favorable cell viability which was more that 90% denoting non cytotoxicity. It was found to be significant among RG (P< 0.0001). The highest cell viability was found after 24 hours among all groups; however, the least viability was found after 48 hours among TG1 and RG, and among TG2 after 72 hours. After 168 hours, there was a non-statistical significant change in cell viability between groups (P= 0.526). there was significant increase in optical density for all groups throughout time intervals (P< 0.0001).Conclusion: Photoinitiated resins are comparable to traditionally used heat polymerized acrylic resin with equivalent cytotoxic effect for long term use. 3D printed photoinitiated resins are biocompatible and suggested for long term intraoral use.