bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-Colonialism Versus Self-Determination
Authors: Paranzino Michelle 
Published: August 2022

Abstract
The 1982 Falklands/Malvinas conflict pitted two of the most foundational principles of postwar international relations—anti-colonialism and self-determination—against each other, creating dilemmas for the great powers and smaller states alike in determining where to place their loyalties. The British consistently upheld the self-determination of the islanders, while portraying the war as a struggle between the forces of democracy and those of dictatorship. Though the United States strove for the appearance of neutrality, support for the United Kingdom resulted in the effective abandonment of the anti-colonialism of the Monroe Doctrine. The Soviet Union viewed the war as an anachronistic return to open imperialist aggression, and backed the fiercely anti-communist military junta in Argentina, even as it waged what was viewed as a “third world war” against the transnational forces of Marxism-Leninism. Meanwhile, the countries of the Western Hemisphere polarised into Latin American demands for decolonisation and the devotion of the Anglophone Caribbean to the principle of self-determination. This division was reflected in the debates and resolutions of the Organization of American States, the Non-Aligned Movement, and the United Nations.
Porous synthetic hydrogel carrying basic fibroblast growth factor with controllable and rapid degradation rate to promote wound healing
Authors: Wu Qian , Gu Huijie , Cui Haiyan , Zhou Shu 
Published: August 2022

Porous hydrogel dressings show breathability and possibility to carry and release basic fibroblast growth factor (bFGF) to promote wound healing. However, the difficult replacement may lead to the secondary damage. Thus, there is an urgent need to develop a method platform to control the degradation rate of hydrogel, so as to realize the on-demand replacement. The present study fabricated a porous hydrogel from co-polymized N,N′-bis(acryloyl) cystamine (BAC), allyl polyethylene glycol 500 (APEG500) and acrylic acid (AA) with the presence of polycaprolactone (PCL). BAC contains disulfide bond, which crosslinked the hydrogel. The pore size of the porous hydrogel was 400–600 μm. Higher content of BAC indicated higher crosslinking density, which reduced swelling ratio of hydrogel, while promoted hydrogel storage modulus. At the same time, the presence of PCL reduced swelling ratio of hydrogel, while promoted hydrogel mechanical properties, endowing hydrogel with tough feature. Porous hydrogels that crosslinked by disulfide bonds immersed in glutathione solution were found to degrade spontaneously and quickly due to the response to glutathione. Both crosslinking density and PCL content affected the degradation rate. The porous hydrogel carrying bFGF was applied to wound, promoting angiogenesis, thus accelerating wound healing within 12 d. Due to the spontaneous and rapid degradation of optimized porous hydrogel on wound within 3 days, there was no operation of removing dressing during treatment, avoiding damage during dressing replacement.
A wireless signal-based sensing framework for robotics
Authors: Jadhav Ninad , Wang Weiying , Zhang Diana , Khatib Oussama , Kumar Swarun , Gil Stephanie 
Published: August 2022

In this paper, we develop the analytical framework for a novel Wireless signal-based Sensing capability for Robotics (WSR) by leveraging a robots’ mobility in 3D space. It allows robots to primarily measure relative direction, or Angle-of-Arrival (AOA), to other robots, while operating in non-line-of-sight unmapped environments and without requiring external infrastructure. We do so by capturing all of the paths that a wireless signal traverses as it travels from a transmitting to a receiving robot in the team, which we term as an AOA profile. The key intuition behind our approach is to enable a robot to emulate antenna arrays as it moves freely in 2D and 3D space. The small differences in the phase of the wireless signals are thus processed with knowledge of robots’ local displacement to obtain the profile, via a method akin to Synthetic Aperture Radar (SAR). The main contribution of this work is the development of (i) a framework to accommodate arbitrary 2D and 3D motion, as well as continuous mobility of both signal transmitting and receiving robots, while computing AOA profiles between them and (ii) a Cramer–Rao Bound analysis, based on antenna array theory, that provides a lower bound on the variance in AOA estimation as a function of the geometry of robot motion. This is a critical distinction with previous work on SAR-based methods that restrict robot mobility to prescribed motion patterns, do not generalize to the full 3D space, and require transmitting robots to be stationary during data acquisition periods. We show that allowing robots to use their full mobility in 3D space while performing SAR results in more accurate AOA profiles and thus better AOA estimation. We formally characterize this observation as the informativeness of the robots’ motion, a computable quantity for which we derive a closed form. All analytical developments are substantiated by extensive simulation and hardware experiments on air/ground robot platforms using 5 GHz WiFi. Our experimental results bolster our analytical findings, demonstrating that 3D motion provides enhanced and consistent accuracy, with a total AOA error of less than 10◦ for 95% of trials. We also analytically characterize the impact of displacement estimation errors on the measured AOA and validate this theory empirically using robot displacements obtained using an off-the-shelf Intel Tracking Camera T265. Finally, we demonstrate the performance of our system on a multi-robot task where a heterogeneous air/ground pair of robots continuously measure AOA profiles over a WiFi link to achieve dynamic rendezvous in an unmapped, 300 m2 environment with occlusions.
Embracing Emotional Pain: A Case Study of Adolescent Suicidality and Spirituality
Authors: Keefner Tamara , Minton Mary , Antonen Kathy 
Published: August 2022

Background: Suicidality continues to be the second leading cause of adolescent death. Nurses are in a prime position to address the emotional pain associated with adolescent suicidality but report skepticism and discomfort. Moreover, spirituality is identified as a protective factor against suicidality, yet a gap exists related to exploring spirituality within the context of the emotional pain associated with adolescent suicidality. Building awareness of adolescents’ spirituality and emotional pain associated with suicidality is essential to address nurse skepticism and discomfort. Aims: The purpose of this study was to explore young adults’ experiences of suicide attempt(s) during adolescence in the context of spirituality using a case study application of participant narratives to Minton and Antonen’s B.L.E.S.S. acronym Method: A multiple-case study design was used to provide an alternative perspective for understanding adolescent suicidality from a spiritual context. Reed’s theory of self-transcendence and the B.L.E.S.S. acronym guided the analysis and interpretation. Convenience online sampling resulted in six adult participants who provided email narratives of their adolescent experiences. Email data collection was guided by Fritz and Vandermause. Analysis of participant narratives followed the protocol of Baxter and Jack. Results: Participant’s narratives revealed self-transcendence that paralleled the five truths about emotional pain and spirituality inherent in the B.L.E.S.S. acronym. Conclusion: This case study provides nurses a guide for counteracting the barriers of skepticism and stigma to promote help-seeking behavior associated with adolescent suicidality. Further research is needed for the application of the B.L.E.S.S. acronym with other population samples.
Clinical parameters at time of admission as prognostic indicators in cats presented for trauma to an emergency centre in New Zealand: a retrospective analysis
Authors: Fitzgerald William R , Cave Nick J , Yozova Ivayla D 
Published: August 2022

Objectives The aims of this study were to describe the clinical features of cats presented for trauma in a first-opinion and referral teaching hospital in New Zealand, and to determine the relationship between those features and outcome. Methods The electronic medical records of cats presented for trauma to the Massey University Pet Emergency Centre between September 2013 and January 2019 were examined, from which the signalment, clinical parameters and patient outcomes were extracted. Cases were assigned an Animal Trauma Triage (ATT) score and Modified Glasgow Coma Scale (MGCS) score. Variables were selected for inclusion in a logistic regression model to predict survival, and backward elimination was used to find the minimal significant model. Results In total, 530 cats met the inclusion criteria. The cause of injury was not known in the majority of cases (38.0%). The most common location of injury was the hindlimbs/pelvis/tail (n = 247; 41%), and skin lacerations/abrasions were the most common specific injury. Multivariate analysis revealed altered mentation (odds ratio [OR] 0.31, P = 0.029), hypothermia (rectal temperature <37.8°C [<100.04°F]; OR 0.45, P = 0.015) and an ATT score ⩾5 (OR 0.13, P <0.001) to be statistically significantly associated with mortality. Conclusions and relevance Altered mentation and hypothermia are easily measurable perfusion parameter abnormalities associated with mortality in cats presenting with trauma. The ATT score appears to be an accurate prognostic indicator in cats presenting with trauma in New Zealand. These results highlight the importance of incorporating a hands-on triage examination in each cat that presents as an emergency after trauma.
Integrated methylome and transcriptome analysis unravel the cold tolerance mechanism in winter rapeseed(Brassica napus L.)
Authors: Zheng Guoqiang , Dong Xiaoyun , Wei Jiaping , Liu Zigang , Aslam Ali , Cui JunMei , Li Hui , Wang Ying , Tian Haiyan , Cao Xiaodong 
Published: August 2022

Abstract
Background
Cytosine methylation, the main type of DNA methylation, regulates gene expression in plant response to environmental stress. The winter rapeseed has high economic and ecological value in China's Northwest, but the DNA methylation pattern of winter rapeseed during freezing stress remains unclear.

Result
This study integrated the methylome and transcriptome to explore the genome-scale DNA methylation pattern and its regulated pathway of winter rapeseed, using freezing-sensitive (NF) and freezing-resistant (NS) cultivars.The average methylation level decreased under freezing stress, and the decline in NF was stronger than NS after freezing stress. The CG methylation level was the highest among the three contexts of CG, CHG, and CHH. At the same time, the CHH proportion was high, and the methylation levels were highest 2 kb up/downstream, followed by the intron region. The C sub-genomes methylation level was higher than the A sub-genomes. The methylation levels of chloroplast and mitochondrial DNA were much lower than the B. napus nuclear DNA, the SINE methylation level was highest among four types of transposable elements (TEs), and the preferred sequence of DNA methylation did not change after freezing stress. A total of 1732 differentially expressed genes associated with differentially methylated genes (DMEGs) were identified in two cultivars under 12 h and 24 h in three contexts by combining whole-genome bisulfite sequencing( and RNA-Seq data. Function enrichment analysis showed that most DMEGs participated in linoleic acid metabolism, alpha-linolenic acid metabolism, carbon fixation in photosynthetic organisms, flavonoid biosynthesis, and plant hormone signal transduction pathways. Meanwhile, some DMEGs encode core transcription factors in plant response to stress.

Conclusion
Based on the findings of DNA methylation, the freezing tolerance of winter rapeseed is achieved by enhanced signal transduction, lower lipid peroxidation, stronger cell stability, increased osmolytes, and greater reactive oxygen species (ROS) scavenging. These results provide novel insights into better knowledge of the methylation regulation of tolerance mechanism in winter rapeseed under freezing stress.
Ligation of left gastric vein may cause delayed gastric emptying after pancreatoduodenectomy: a retrospective study
Authors: Kimura Koichi , Minagawa Ryosuke , Izumi Takuma , Otake Akihiko , Aoyagi Takehiko , Taniguchi Daisuke , Yano Hiroko , Kajiwara Yuichiro , Minami Kazuhito , Nishizaki Takashi 
Published: August 2022

AbstractBackgroundThis study aimed to determine which running pattern of the left gastric vein (LGV) is most frequently ligated in subtotal stomach-preserving pancreatoduodenectomy (SSPPD) and how LGV ligation affects delayed gastric emptying (DGE) after SSPPD.MethodsWe retrospectively analysed 105 patients who underwent SSPPD between January 2016 and September 2021. We classified the running pattern of LGV as follows: type 1 runs dorsal to the common hepatic artery (CHA) or splenic artery (SpA) to join the portal vein (PV), type 2 runs dorsal to the CHA or SpA and joins the splenic vein, type 3 runs ventral to the CHA or SpA and joins the PV, and type 4 runs ventral to the CHA or SpA and joins the SpV. Univariate and multivariate analyses were used to identify differences between patients with and without DGE after SSPPD.ResultsType 1 LGV running pattern was observed in 47 cases (44.8%), type 2 in 23 (21.9%), type 3 in 12 (11.4%), and type 4 in 23 (21.9%). The ligation rate was significantly higher in type 3 (75.0%) LGVs (p < 0.0001). Preoperative obstructive jaundice (p = 0.0306), LGV ligation (p < 0.0001), grade B or C pancreatic fistula (p = 0.0116), and sepsis (p = 0.0123) were risk factors for DGE in the univariate analysis. Multivariate analysis showed that LGV ligation was an independent risk factor for DGE (odds ratio: 13.60, 95% confidence interval: 3.80–48.68,p < 0.0001).ConclusionType 3 LGVs are often ligated because they impede lymph node dissection; however, LGV preservation may reduce the occurrence of DGE after SSPPD.
Acute dizziness and mental alteration associated with Moderna COVID-19 vaccine: a case report
Authors: Pinzon Rizaldy Taslim , Haryono Fillia Kristyawati , Darmawan Nikolaus Erik , Salikim Mia Amelia Mutiara , Veronica Vanessa 
Published: August 2022

Abstract
Background
Due to a rising number of COVID-19 cases, the Indonesian government implemented public health programs to lower the rate. Since January 2021, one of the government’s primary policies has been the COVID-19 immunization program. Recently, the Moderna messenger ribonucleic acid (mRNA) vaccine is one of the COVID-19 vaccines used in Indonesia. Based on some research, Moderna has possible side effects throughout the body, including neurological symptoms.

Case presentation
We describe a 39-year-old female with uncontrolled hypertension who showed behavioral change, communication difficulty, social withdrawal, and a confused state within 7 days from getting her first dose of the Moderna vaccine. The patient had a history of febrile convulsion in childhood. An increase of neutrophil-to-lymphocyte ratio (16.9) and C-reactive protein level (31.75 mg/L) indicates ongoing inflammation. Head CT scan shows no abnormalities. She received ceftriaxone, citicoline, and methylprednisolone. The patient was discharged on the seventh day and completely recovered 1 week later. This study is the first case report of encephalopathy following the administration of the Moderna COVID-19 vaccine reported in Indonesia up to our knowledge.

Conclusion
Encephalopathy related to the Moderna COVID-19 vaccine should be acknowledged as an adverse effect of the Moderna COVID-19 vaccine.
Temporally ordered associations between type 2 diabetes and brain disorders – a Danish register-based cohort study
Authors: Wimberley Theresa , Horsdal Henriette T. , Brikell Isabell , Laursen Thomas M. , Astrup Aske , Fanelli Giuseppe , Bralten Janita , Poelmans Geert , Gils Veerle Van , Jansen Willemijn J. , Vos Stephanie J. B. , Bertaina-Anglade Valérie , Camacho-Barcia Lucia , Mora-Maltas Bernat , Fernandez-Aranda Fernando , Bonet Mònica B. , Salas-Salvadó Jordi , Franke Barbara , Dalsgaard Søren 
Published: August 2022

AbstractBackgroundType 2 diabetes mellitus (T2DM) is linked with several neurodegenerative and psychiatric disorders, either as a comorbid condition or as a risk factor. We aimed to expand the evidence by examining associations with a broad range of brain disorders (psychiatric and neurological disorders, excluding late-onset neurodegenerative disorders), while also accounting for the temporal order of T2DM and these brain disorders.MethodsIn a population-based cohort-study of 1,883,198 Danish citizens, born 1955–1984 and followed until end of 2016, we estimated associations between T2DM and 16 brain disorders first diagnosed between childhood and mid-adulthood. We calculated odds ratios (OR) and hazard ratios (HR) with 95% confidence intervals (CI) in temporally ordered analyses (brain disorder diagnosis after T2DM and vice versa), adjusted for sex, age, follow-up, birth year, and parental factors.ResultsA total of 67,660 (3.6%) of the study population were identified as T2DM cases after age 30 and by a mean age of 45 years (SD of 8 years). T2DM was associated with most psychiatric disorders. Strongest associations were seen with other (i.e. non-anorectic) eating disorders (OR [95% CI]: 2.64 [2.36–2.94]) and schizophrenia spectrum disorder (2.73 [2.63–2.84]). Among neurological disorders especially inflammatory brain diseases (1.73 [1.57–1.91]) and epilepsy (1.67 [1.60–1.75]) were associated with T2DM. Most associations remained in both directions in the temporally ordered analyses. For most psychiatric disorders, associations were strongest in females.ConclusionsT2DM was associated with several psychiatric and neurological disorders, and most associations were consistently found for both temporal order of disorders. This suggests a shared etiology of T2DM and those brain disorders. This study can form the starting point for studies directed at further elucidating potential causal links between disorders and shared biological mechanisms.
Birt-Hogg-Dubé syndrome in apparent primary spontaneous pneumothorax patients; results and recommendations for clinical practice
Authors: Sriram Jincey D. , van de Beek Irma , Johannesma Paul C. , van Werkum Michiel H. , van der Wel Tijmen J. W. T. , Wessels Elise M. , Gille Hans J. J. P. , Houweling Arjan C. , Postmus Pieter E. , Smit Hans J. M. 
Published: August 2022

Abstract
Background
Birt-Hogg-Dubé syndrome (BHD) is an inherited disease caused by pathogenic variants in the FLCN gene. One of the characteristics is the increased risk for spontaneous pneumothorax, likely due to the presence of pulmonary cysts mainly distributed under the carina. Due to variable expression and lack of awareness, BHD is likely to be underdiagnosed. We aimed to examine the prevalence of BHD in patients presenting with an apparent primary spontaneous pneumothorax and to evaluate the contribution of chest CT in establishing the diagnosis.

Methods
Patients who presented with apparent primary spontaneous pneumothorax between 2004 and 2017 in a large Dutch teaching hospital were enrolled in this quantitative cross-sectional study. A questionnaire was sent to eligible patients. Patients who completed the questionnaire and consented to further participation were invited to visit the hospital for genetic testing and low dose, volumetric chest CT.

Results
Genetic testing was performed in 88 patients with apparent primary spontaneous pneumothorax. Three patients were found to have a pathogenic variant in the FLCN gene (3.4%). No variants of unknown significance were detected. Pulmonary cysts were detected in 14 out of 83 participants with an available chest CT, six had more than one cyst. All three patients with BHD had multiple pulmonary cysts.

Conclusions
Based on previous literature and the present study, we believe that performing a chest CT in every patient presenting with primary spontaneous pneumothorax is justified. Subsequent genetic testing of the FLCN gene should be considered when multiple pulmonary cysts are present.

Trial registration

The study was registered at clinicaltrials.gov with reference NCT02916992.

Summary at a glance
Three out of 88 patients with an apparent primary spontaneous pneumothorax were diagnosed with Birt-Hogg-Dubé syndrome in this study and all three had multiple pulmonary cysts. We believe that performing a chest CT in every patient with an apparent primary spontaneous pneumothorax is justified to identify underlying diseases.
Irrigation techniques used in spine surgery for surgical site infection prophylaxis: a systematic review and meta-analysis
Authors: Torres Kabir A. , Konrade Elliot , White Jacob , Tavares Junior Mauro Costa M. , Bunch Joshua T. , Burton Douglas , Jackson R. Sean , Birlingmair Jacob , Carlson Brandon B. 
Published: August 2022

Abstract
Background
The greater likelihood of morbidity, mortality, length of hospital stays and poorer long-term outcomes as a result of surgical site infections secondary to spinal surgery makes prophylactic measures an imperative focus. Therefore, the aim of this review was to evaluate the available research related to the efficacy of different intraoperative irrigation techniques used in spinal surgery for surgical site infection (SSI) prophylaxis.

Methods
We performed a comprehensive search using Ovid Medline, EMBASE, Web of Science and the Cochrane library pertaining to this topic. Our meta-analysis was conducted according to PRISMA guidelines. The inclusion criteria consist of spine surgeries with intraoperative use of any wound irrigation technique, comparison groups with a different intraoperative irrigation technique or no irrigation, SSI identified with bacterial cultures or clinically in the postoperative period, reported SSI rates. Data extracted from eligible studies included, but was not limited to, SSI rates, irrigation technique and control technique. Exclusion criteria consist of articles with no human subjects, reviews, meta-analyses and case control studies and no details about SSI identification or rates. Pooled risk ratios were calculated. A meta-analysis was performed with a forest plot to determine risk estimates’ heterogeneity with I2 index, Q-statistic, and p value under a random-effects model. Funnel plot was used to assess publication bias. All databases were last checked on January, 2022. PROBAST tool was used to assess both risk of bias and applicability concerns.

Results
After reviewing 1494 titles and abstracts, 18 articles met inclusion criteria. They included three prospective randomized-controlled trials, 13 retrospective cohort studies, two prospective cohort studies. There were 54 (1.8%) cases of SSIs in the povidone-iodine irrigation group (N = 2944) compared to 159 (4.6%) in the control group (N = 3408). Using intraoperative povidone-iodine wound irrigation produced an absolute risk reduction of 2.8%. Overall risk ratio was 0.32 (95% CI 0.20–0.53, p < 0.00001). In a global analysis, study heterogeneity and synthesizing mostly retrospective data were primary limitations.

Conclusion
The most evidence exists for povidone-iodine and has Level 2 evidence supporting SSI reduction during spinal surgery. Other antiseptic solutions such as dilute chlorhexidine lack published evidence in this patient population which limits the ability to draw conclusions related to its use in spinal surgery.

Level of Evidence
II – Systematic Review with Meta-Analysis.