bluuebunny/crossref_metadata_2025_split huggingface dataset:
Topochemical, Single‐Crystal‐to‐Single‐Crystal [2+2] Photocycloadditions Driven by Chalcogen‐Bonding Interactions
Authors: Alfuth Jan , Jeannin Olivier , Fourmigué Marc 
Published: July 2022

AbstractThe face‐to‐face association of (E)‐1,2‐di(4‐pyridyl)ethylene (bpen) molecules into rectangular motifs stabilized for the first time by chalcogen bonding (ChB) interactions is shown to provide photoreactive systems leading to cyclobutane formation through single‐crystal‐to‐single‐crystal [2+2] photodimerizations. The chelating chalcogen bond donors are based on original aromatic, ortho‐substituted bis(selenocyanato)benzene derivatives 1–3, prepared from ortho‐diboronic acid bis(pinacol) ester precursors and SeO2 and malononitrile in 75–90 % yield. The very short intramolecular Se⋅⋅⋅Se distance in 1–3 (3.22–3.24 Å), a consequence of a strong intramolecular ChB interaction, expands to 3.52–3.54 Å in the chalcogen‐bonded adducts with bpen, a distance (<4 Å) well adapted to the face‐to‐face association of the bpen molecules into the reactive position toward photochemical dimerization.
Anode‐Free Lithium–Sulfur Cells Enabled by Rationally Tuning Lithium Polysulfide Molecules
Authors: Ren Yuxun , Bhargav Amruth , Shin Woochul , Sul Hyunki , Manthiram Arumugam 
Published: July 2022

AbstractThe two major barriers of practical lithium–sulfur batteries are the poor reversibility of lithium‐metal anode and sluggish kinetics of sulfur cathode. Here, we report a simple yet cogent, molecular tailoring approach for lithium polysulfides, enabling a synergistic enhancement of anode reversibility and cathode kinetics. We show that SnI4coordinates with lithium polysulfides to form soluble complexes, resulting in a Li2SnS3‐rich anode interphase layer. As Li2SnS3is stable against parasitic reactions and has a lower ionic resistance over cycling, the Li plating/stripping efficiency is greatly improved. In addition, the formation of soluble complexes between SnI4and lithium polysulfides play a non‐negligible role in suppressing the clustering behavior of lithium polysulfide molecules, resulting in a significant enhancement in sulfur conversion kinetics under lean electrolyte conditions. The synergistic improvement is validated in anode‐free, lean‐electrolyte pouch cells with a Li2S cathode that displays capacity retention of 78 % after 100 cycles.
The insecure skin‐ego: Conspiracy theories as a source of containment in a pandemic
Authors: Mohammadpour‐Yazdi Ahmad‐Reza , Dabbagh Hossein 
Published: July 2022

AbstractIn analyzing the psychological reactions to the recent COVID‐19 pandemic, we have tried to show that the existing societal protective skin that gives unity to people by creating a secure containment was too thin and fragile to cope with an annihilation situation such as the pandemic. This healthy and protective societal skin acts continuously as a maternal environment, providing physical and mental security. As a modest contribution, we provide psychoanalytic, social, cultural, and political analyses of the conspiracy theories and infodemics in the mid‐COVID‐19 era. We extend Anzieu's theory of skin‐ego from a maternal‐centered conceptualization to one based on a wider range of caregivers, including politicians, health care professionals, scientists, and researchers—who act as the suppliers of containment. During the pandemic, the common protective skin showed initial flexibility as it tried to regenerate a secure common skin with the help of the health care system and other state organizations responsible for managing the COVID‐19 pandemic. However, the common protective skin is under continuous attack by various politicians around the world, like the hyper‐masculine figure of Donald Trump who attacked this common skin, increasing the insecurity and helplessness of people. Like hermit crabs, thin‐skinned people with insecure skin‐egos sought refuge inside the shell of Trump's safer and thicker skin. A shell of conspiracy theories and infodemics provided by crustacean Trump functioned as a thick, protective skin. To illustrate our ideas, we present events and reactions from the pandemic and also cite two illustrative examples—the story of Noah's Ark and the children's classic, The Three Little Pigs.
Silica‐based Nanoparticles for Enzyme Immobilization and Delivery
Authors: Zhao Liang , Zhang Yue , Yang Yannan , Yu Chengzhong 
Published: July 2022

AbstractEnzymes play an indispensable role in biosystems, catalyzing a variety of chemical and biochemical reactions with exceptionally high efficiency and selectivity. These features render them uniquely positioned in developing novel catalytic systems and therapeutics. However, their practical application is largely hindered by the vulnerability, low reusability and the inability to overcome the biological barriers of enzymes. Silica‐based nanoparticles (SNPs) are a classic family of nanomaterials with tunable physicochemical properties, making them ideal candidates to address the intrinsic shortcomings of natural enzymes. SNPs not only improve the activity and durability of enzymes, but also provide precise spatiotemporal control over their intracellular as well as systemic biodistributions for boosting the catalytic outcome. Herein, the recent progress in SNPs for enzyme immobilization and delivery is summarized. The therapeutic applications, including cancer therapy and bacterial inhibition, are particularly highlighted. Our perspectives in this field, including current challenges and possible future research directions are also provided.
A novel clinical tool to predict cancer‐specific survival in patients with primary pelvic sarcomas: A large population‐based retrospective cohort study
Authors: Huang Chao , Su Qiang , Ding Zichuan , Zeng Weinan , Zhou Zongke 
Published: July 2022

AbstractBackgroundPrimary osseous sarcoma of the pelvis is rare and has a particularly sinister outcome. This study aims to identify independent prognostic factors of cancer‐specific survival (CSS) in patients with primary pelvic sarcoma (PS) and develop a nomogram to predict 3‐, 5‐, and 10‐year probability of CSS in these patients.MethodsThe Surveillance, Epidemiology, and End Results (SEER) database was used to identify 416 patients with primary PS, who were divided into two groups: a training cohort and a validation cohort. Univariate and multivariate Cox analyses were used to screen independent prognostic factors in patients with primary PS. Based on these independent prognostic factors, a prognostic nomogram was developed to predict 3‐, 5‐, and 10‐year probability of CSS. The nomogram's predictive performance and clinical value were evaluated using the calibration curve, receiver operating characteristic (ROC) curve, and decision curve analysis (DCA). Finally, a mortality risk stratification system was developed.ResultsTumor size, tumor stage, histological type, surgery, and chemotherapy were identified as independent prognostic factors for the CSS of primary PS patients. Based on these factors, a nomogram was created to predict the 3‐, 5‐, and 10‐year probability of CSS in these patients. The calibration curve, ROC, and DCA indicated that the nomogram performed well and was appropriate for clinical use, with 3‐, 5‐, and 10‐year areas under ROC curve all higher than 0.800. Furthermore, the nomogram‐based mortality risk stratification system could effectively divide these patients into three risk subgroups.ConclusionsThe nomogram constructed in this study could accurately predict 3‐, 5‐, and 10‐year probability of CSS in patients with primary PS. Clinicians can use the nomogram to categorize these patients into risk subgroups and provide personalized treatment plans.
Isolation of Some Phenolic Compounds from Plantago subulata L. and Determination of Their Antidiabetic, Anticholinesterase, Antiepileptic and Antioxidant Activity
Authors: Özaslan Muhammet Serhat , Sağlamtaş Rüya , Demir Yeliz , Genç Yasin , Saraçoğlu İclal , Gülçin İlhami 
Published: July 2022

AbstractIn the current study, some phenolic compounds, including acteoside, isoacteoside, echinacoside, and arenarioside purified and characterized from Plantago subulata. These compounds were tested for its antioxidant potential, including Fe3+ and Cu2+ reductive ability and Fe2+ chelating effects. The inhibitory effects of isolated phenolic compounds were tested towards human carbonic anhydrase I and II isoenzymes (hCA I and hCA II), butyrylcholinesterase (BChE) acetylcholinesterase (AChE), aldose reductase (AR) and α‐glycosidase (α‐gly). Ki values were found these compounds in range of 0.24±0.05–1.38±0.34 μM against hCA I, 0.194±0.018–1.03±0.06 μM against hCA II, 0.043±0.01–0.154±0.02 μM against AChE, 3.92±1.08–11.93±4.45 μM against BChE, 0.082±0.0008–1.68±0.42 μM against AR, and 6.93±2.74–17.17±6.70 μM against α‐glycosidase. As a result, isolated compounds displayed inhibition effects against studied all metabolic enzymes. They are promising candidates for treating disorders like Alzheimer's disease, diabetes mellitus, glaucoma, leukemia, and epilepsy.
Transformation of Platinum Single‐Atom Catalysts to Single‐Atom Alloys on Supported Nickel: TEM and XAS Spectroscopic Investigation
Authors: Kim Sunkyu , Sasmaz Erdem 
Published: July 2022

AbstractThe well‐dispersed Pt atoms on Ni have shown excellent coke resistance during methane reforming. In this work, we performed detailed characterization experiments using aberration‐corrected high‐angle annular dark‐field scanning transmission electron microscopy (AC‐HAADF‐STEM), and X‐ray absorption spectroscopy (XAS) to elucidate the formation of different Pt structures with respect to Pt/Ni atomic ratios. The Pt−Ni single‐atom alloys (SAAs) in Pt/Ni‐CeO2@SiO2 yolk‐shell nanotube structures are synthesized by reducing Pt single atoms supported on the NiO surface as single‐atom catalysts (SACs). Pt−Ni SAAs show Pt−Ni contribution in the first shell with the coordination number of 5 without any Pt−Pt and Pt−O interactions, implying Pt atoms are isolated on the outermost layer of Ni species. However, Pt clusters can be detected at Pt/Ni atomic ratios higher than 0.008. The well‐dispersed Pt single atoms on Ni show high activity while maintaining their structure in dry reforming of methane condition at 773 K, verifying the excellent stability of the Pt−Ni SAA morphology.
Economic outcomes for transitioning to organic forage production
Authors: Kubesch Jonathan O. C. , Nave R. L. G. , Griffith A. P. , Cui S. , Bates G. E. 
Published: July 2022

AbstractResearch on the use of forages to transition cropland to organic production is limited. Our objective was to determine the cost of transitioning from conventional to organic production using perennial and annual forage systems. The study was conducted at the Middle Tennessee AgResearch and Education Center, in Spring Hill, TN. Five forage treatments were compared: tall fescue [Schedonorus arundinaceus (Schreb.) Dumort.] monoculture, bermudagrass [Cynodon dactlyon (L.) Pers.] monoculture, tall fescue and alfalfa (Medicago sativa L.) mixture, bermudagrass and alfalfa mixture, and an annual rotation of a cool‐season mixture, including winter wheat (Triticum aestivum L.) and winter pea (Pisum sativum L.), and a warm‐season mixture of sorghum–sudangrass [Sorghum bicolor (L.) Moench × S.orghum sudanese (Piper) Stapf] and cowpea [Vigna unguiculata (L.) Walp.]. Perennial forages were established in 2017 and 2018 following orchard removal and a fallow period. Regular production measurements began in 2019 when the plots achieved full organic certification status. Tall fescue had the lowest cost for the overall transition period. However, on a cost per unit of dry matter (DM) forage mass and on a cost per unit of crude protein (CP) basis, all treatments were similar, with a range between US$0.02 and $0.03 lb–1 for DM forage mass and between $0.15 and $0.20 lb–1 for CP, except for the more costly bermudagrass monoculture that was $0.06 lb–1 DM forage mass and $0.40 lb–1 CP. Given the lack of a premium during the transition period, tall fescue was the most cost‐effective transition forage.
Ethylene‐Coordinative Chain‐Transfer Polymerization‐Induced Self‐Assembly (CCTPISA)
Authors: Baulu Nicolas , Langlais Marvin , Dugas Pierre‐Yves , Thuilliez Julien , Jean‐Baptiste‐dit‐Dominique François , Lansalot Muriel , Boisson Christophe , D'Agosto Franck 
Published: July 2022

AbstractBlock copolymers based on ethylene (E) and butadiene (B) were prepared using the ansa‐bis(fluorenyl) complex {Me2Si(C13H8)2Nd(BH4)2Li(THF)}2 in combination with (n‐Bu)(n‐Oct)Mg (BOMAG) as a chain‐transfer agent. The diblock copolymers incorporating a soft poly(ethylene‐co‐butadiene) segment, called ethylene butadiene rubber (EBR), and a hard polyethylene (PE) one were obtained by simply adjusting the different feeds of monomers during the polymerization. The soluble EBR block was formed first by feeding the catalytic system dissolved in toluene at 70 °C with a mixture of ethylene and butadiene (E/B molar ratio 80 : 20). Then the feeding was stopped leading to the consumption of a large part of the residual monomers. The reactor was finally fed with ethylene to form the PE block. By varying the molar mass of the latter, it is shown that the resulting soft‐b‐hard block copolymers can self‐assemble simultaneously to the growth of the PE block in agreement with a polymerization‐induced self‐assembly (PISA) mechanism. The self‐assembly is discussed considering the reaction conditions, the crystallization of the PE block, and the polymerization mechanism involved.
Prior antihistamine agent successfully impaired cutaneous adverse reactions to COVID‐19 vaccine
Authors: Nanamori Hikaru , Sawada Yu , Sato Sayaka , Hara Reiko , Minokawa Yoko , Sugino Hitomi , Saito‐Sasaki Natsuko , Yamamoto Kayo , Okada Etsuko , Nakamura Motonobu 
Published: July 2022

AbstractThe coronavirus disease 2019 (COVID‐19) vaccine is positively changing the health crises of this pandemic and is currently essential to overcome the COVID‐19 pandemic. The vaccine shows high efficacy against the infection and impairs the severity of symptoms. However, this vaccination is associated with concerns, such as vaccine‐associated adverse reactions, which are currently highlighted issues for clinicians. We experienced two cases of mild cutaneous adverse reaction following COVID‐19 vaccine administration, which was successfully controlled by prior administration of the antihistamine agent fexofenadine 3 days before COVID‐19 vaccination for 7 days.
Separation of Cesium Using Magnetic Copper Hexacyanoferrate/Biochar/Fe3O4
Authors: Xu Li , Tao Qinqin , Dai Ying 
Published: July 2022

AbstractIn this study, a novel cesium scavenger, magnetic copper hexacyanoferrate (III)/pomelo peel biochar (CuHCF‐MPC), is prepared. CuHCF‐MPC exhibits remarkable Cs+ adsorption properties including rapid kinetics, stability over a wide pH range (pH ≈3–10), high cesium adsorption capacity (145.65 mg g−1 at pH 7), high removal efficiency (>90%) and high Kd value (49 000 mL g−1) even in the presence of competitive cations (K+, Na+, Mg2+, and Ca2+) at high concentration. The kinetic behavior of cesium adsorption onto CuHCF‐MPC can be elucidated with the pseudo‐second‐order kinetic model. The adsorption is classified as an endothermic and spontaneous process as proved by ΔH < 0, ΔG < 0. The positive results suggest CuHCF‐MPC is an economic, environment‐friendly, and promising task‐specific adsorbent of cesium.
Soft tissue sarcoma incidences and clinical characteristics are significantly different in France and Taiwan
Authors: Chen Tom Wei‐Wu , Chiang Ruru Chun‐Ju , Le Cesne Alex , Hsieh Yu‐Chun , Italiano Antoine , Yang Ya‐Wen , Penel Nicolas , Lee Wen‐Chung , Bompas Emmanuelle , Valentin Thibaud , Anract Philippe , Firmin Nelly , Duffaud Florence , Cheng Ann‐Lii , Ducimetiere Francoise , Chan K. Arnold , Blay Jean‐Yves 
Published: July 2022

BackgroundThe incidence of different soft tissue sarcoma (STS) histotypes among ethnic and geographic populations has not been comprehensively investigated.MethodsData from 2013 to 2016 were obtained from national cancer registry databases in France and Taiwan. Liposarcoma (LPS), leiomyosarcoma (LMS), angiosarcoma (AS), synovial sarcoma (SS), and malignant peripheral nerve sheath tumor (MPNST) were selected as index STSs to estimate the age‐standardized incidence rates (ASRs) and other clinical features between patients.ResultsIn total, 9398 patients (7148 from France and 2250 from Taiwan) were included. The ASRs of AS (5.4 vs. 2.8) and MPNST (2.0 vs. 1.0) were significantly higher in Taiwan; France had significantly higher ASRs for LPS (12.0 vs. 10.0), LMS (9.7 vs. 7.6), and SS (1.7 vs. 1.2). Patients in Taiwan with LMS or LPS were younger than their French counterparts. With regard to the distribution according to primary anatomic site, French patients had higher odds for extremity and truncal LMS (odds ratio [OR], 2.84; p < .001), AS (OR, 2.67; p < .001), MPNST (OR, 1.55; p = .027), and LPS (OR, 1.38; p < .001) and for breast AS (OR, 10.58; p < .001). Taiwanese patients had higher odds for liver AS (OR, 10.72; p < .001) and uterine LMS (OR, 3.21; p < .001). SS age and distribution according to primary anatomic site did not differ significantly between the French and Taiwanese populations.ConclusionsSignificant differences in the incidence and clinical characteristics of index STS suggested that geographic (environmental) and ethnicity factors likely play a vital role in the pathogenesis of STS.
Risk factors for breast cancer–related lymphedema in patients undergoing 3 years of prospective surveillance with intervention
Authors: Koelmeyer Louise A. , Gaitatzis Katrina , Dietrich Mary S. , Shah Chirag S. , Boyages John , McLaughlin Sarah A. , Taback Bret , Stolldorf Deonni P. , Elder Elisabeth , Hughes T. Michael , French James R. , Ngui Nicholas , Hsu Jeremy M. , Moore Andrew , Ridner Sheila H. 
Published: July 2022

BackgroundTo evaluate risk factors (treatment‐related, comorbidities, and lifestyle) for breast cancer–related lymphedema (BCRL) within the context of a Prospective Surveillance and Early Intervention (PSEI) model of care for subclinical BCRL.MethodsThe parent randomized clinical trial assigned patients newly diagnosed with breast cancer to PSEI with either bioimpedance spectroscopy (BIS) or tape measurement (TM). Surgical, systemic and radiation treatments, comorbidities, and lifestyle factors were recorded. Detection of subclinical BCRL (change from baseline of either BIS L‐Dex ≥6.5 or tape volume ≥ 5% and < 10%) triggered an intervention with compression therapy. Volume change from baseline ≥10% indicated progression to chronic lymphedema and need for complex decongestive physiotherapy. In this secondary analysis, multinomial logistic regressions including main and interaction effects of the study group and risk factors were used to test for factor associations with outcomes (no lymphedema, subclinical lymphedema, progression to chronic lymphedema after intervention, progression to chronic lymphedema without intervention). Post hoc tests of significant interaction effects were conducted using Bonferroni‐corrected alphas of .008; otherwise, an alpha of .05 was used for statistical significance.ResultsThe sample (n = 918; TM = 457; BIS = 461) was female with a median age of 58.4 years. Factors associated with BCRL risk included axillary lymph node dissection (ALND) (p < .001), taxane‐based chemotherapy (p < .001), regional nodal irradiation (RNI) (p ≤ .001), body mass index >30 (p = .002), and rurality (p = .037). Mastectomy, age, hypertension, diabetes, seroma, smoking, and air travel were not associated with BCRL risk.ConclusionsWithin the context of 3 years of PSEI for subclinical lymphedema, variables of ALND, taxane‐based chemotherapy, RNI, body mass index >30, and rurality increased risk.
Adaptive group‐aware topic model for venue recommendation
Authors: Li RuiChang , Meng Xiangwu , Zhang Yujie 
Published: July 2022

SummaryVenue recommendation plays a vital role in helping the user discovers interesting locations. However, most of the existing studies have never considered the case of multiple people visiting a venue together, such as inviting friends to dinner, so they ignore the influence of group preference on making decisions. Furthermore, the participants' influence on the inviter's decision is also affected by participation time, venue category, and visiting sequence. In this article, we propose an adaptive group‐aware topic model (AGATM) to provide TOP‐K venue recommendations. The model considers the individual's personalized preferences and group preferences at different times to provide venue recommendations by simulating the process of making decisions for venues. We conduct extensive experiments on two real datasets to evaluate the performance of our proposed method. The experimental results show that our model outperforms existing benchmark algorithms.
Structural Regulation of Oxygen Vacancy‐Rich K0.5Mn2O4Cathode by Carbon Hybridization for Enhanced Zinc‐Ion Energy Storage
Authors: Wang Shuting , Yuan Guanghui , Yang Jiangpeng , Bai Jintao , Wang Gang , Yan Junfeng 
Published: July 2022

AbstractHigh‐voltage manganese‐based materials are considered as promising cathode materials for aqueous zinc‐ion batteries (AZIBs). Herein, oxygen vacancy‐rich K0.5Mn2O4sheets were anchored uniformly onto honeycomb‐like interconnected carbon nanoflakes (CNF@K0.5Mn2O4) for AZIB cathode applications. In the composite, the CNFs provided excellent intergranular electron transport capability, while the oxygen vacancies enhanced the electron transport efficiency inside crystals, and the embedded K ions expanded the interlayer spacing and stabilized the layered crystal structure. A reversible specific capacity of 241 mAh g−1could be maintained by the composite at 0.5 A g−1for 400 cycles. A combination of ex‐situ analytical methods and density functional theory calculations was carried out to elucidate the electrochemical mechanism of reversible zinc storage. In addition, flexible quasi‐solid‐state batteries of Zn//CNF@K0.5Mn2O4were constructed by substituting the traditional aqueous electrolyte for a quasi‐solid‐state gel electrolyte, which worked efficiently and exhibited high bending durability.