bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual Redox Active Sites N‐C@Ni2P/NiSe2 Heterostructure Supercapacitor Integrated with Triboelectric Nanogenerator toward Efficient Energy Harvesting and Storage
Authors: Gao Xiangyang , Zhang Yuanzheng , Yin Shukun , Mao Yiqian , Gui Jinzheng , Li Jingxing , Zhao Yafei , Sun Chengliang , Guo Shishang 
Published: July 2022

AbstractExploring efficient energy systems with integrated energy harvesting and storage toward sustainable power sources is an extremely promising solution for alleviating the energy crisis but nevertheless remains an arduous challenge. Here, a high‐efficient self‐charging power system (SCPS) by integrating solid‐state asymmetric supercapacitors device (SASD) and rotational triboelectric nanogenerator (RTENG) to achieve efficient energy harvesting and storage is reported. Dual redox active sites Ni2P/NiSe2 heterostructure is homogeneously inlaid on N‐C (N‐C@Ni2P/NiSe2) via an in situ phosphoselenization, which achieves the maximum exposure of active sites and prevents the aggregation of nanoparticles. The ingeniously designed N‐C@Ni2P/NiSe2 heterostructure features high activity dual redox sites, well‐defined heterointerface, and stable superhighway conductive support, which facilitates high electrochemical reaction efficiency, accelerated reaction kinetics, and enhanced electrochemical stability, thus achieving high capacitance and excellent stability. Meanwhile, the SASD delivers high energy density and long lifespan. Furthermore, the RTENG exhibits high output performance, enabling efficient energy harvesting. The SCPS can reach a voltage of 3.8 V within 40 s, and continuously power electronics. It is believed that the proposed survey based on the design and integration of dual redox active sites heterostructure will offer a new prospect for next‐generation sustainable power sources.
Unveiling the Dynamic Oxidative Etching Mechanisms of Nanostructured Metals/Metallic Oxides in Liquid Media Through In Situ Transmission Electron Microscopy
Authors: Zhang Junyu , Sun Zhefei , Kang Zewen , Lin Haichen , Liu Haodong , He Yang , Zeng Zhiyuan , Zhang Qiaobao 
Published: July 2022

AbstractOxidative etching in nanostructured metals and metallic oxides plays a fundamental role in numerous areas of chemical synthesis and materials processing for the semiconductor industry. An in‐depth understanding of the oxidative etching mechanisms is of great significance to design various fascinating nanomaterials for practical application. In situ liquid cell transmission electron microscopy (TEM) has the merits of high temporal and spatial resolutions in real‐time, and thus it can provide solid evidence directly for the dynamic evaluation of oxidative etching in nanostructured materials that occur in solution. Herein, the recent progress of oxidative etching in nanostructured metals and metallic oxides is overviewed. First, the advancements in liquid cells designs are briefly introduced for in situ TEM observation. Subsequently, in situ liquid cell TEM/STEM advances for the oxide etching mechanisms in different surface chemistry surroundings are systematically described. In addition, both the galvanic replacement and electrochemical etching reactions are also discussed. Finally, the challenges and opportunities in utilizing the in situ liquid cell TEM technique to visualize a specific dynamic oxidative etching process are proposed. This review will provide deep insights into dynamic changes in oxidative etching processes of nanostructured materials and assist in formulating design rules for developing high‐end advanced devices.
Fluorinated Interfaces for Efficient and Stable Low‐Temperature Carbon‐Based CsPbI2Br Perovskite Solar Cells
Authors: Zhang Xiang , Zhang Dan , Zhou Yuan , Du Yunxiao , Jin Junjun , Zhu Zhenkun , Wang Zhen , Cui Xiaxia , Li Jinhua , Wu Sujuan , Zhang Jing , Tai Qidong 
Published: July 2022

AbstractCarbon‐based inorganic perovskite solar cells (C‐PSCs) have attracted intensive attention owing to their low cost and superior thermal stability. However, the bulk defects in perovskites and interfacial energy level mismatch seriously undermine their performance. To overcome these issues, a multifunctional dual‐interface engineering is proposed with a focus on low‐temperature CsPbI2Br C‐PSCs, where the potassium trifluoroacetate (KTFA) and the 4‐trifluorophenyl methylammonium bromide (CF3PMABr) are introduced beneath and on top of the perovskite layer, respectively. It is found that TFA‐ ions locate at the SnO2/CsPbI2Br interface, whereas a small amount of K+ ions diffuse into perovskite lattice to participate in nucleation and crystallization, resulting in more favored interfacial energy level alignment, improved film quality, passivated interfacial defects, released interfacial strain, as well as suppressed charge recombination and ion migration. Meanwhile, the CF3PMABr passivates I/Br vacancies and forms 2D perovskite capping layer to facilitate hole extraction at the CsPbI2Br/carbon interface. As a result, a remarkable power conversion efficiency (PCE) of 14.05% with an open‐circuit voltage of 1.273 V is achieved. To the best of the authors’ knowledge, it is currently the highest PCE reported for low‐temperature CsPbI2Br C‐PSCs. Furthermore, the nonencapsulated device exhibits improved moisture, thermal, and illumination stability in ambient air.
Rapid Ultratough Topological Tissue Adhesives
Authors: Cintron‐Cruz Juan A. , Freedman Benjamin R. , Lee Matthew , Johnson Christopher , Ijaz Hamza , Mooney David J. 
Published: July 2022

AbstractTissue adhesives capable of achieving strong and tough adhesion in permeable wet environments are useful in many biomedical applications. However, adhesion generated through covalent bond formation directly with the functional groups of tissues (i.e., COOH and NH2 groups in collagen), or using non‐covalent interactions can both be limited by weak, unstable, or slow adhesion. Here, it is shown that by combining pH‐responsive bridging chitosan polymer chains and a tough hydrogel dissipative matrix one can achieve unprecedented ultratough adhesion to tissues (>2000 J m−2) in 5–10 min without covalent bond formation. The strong non‐covalent adhesion is shown to be stable under physiologically relevant conditions and strongly influenced by chitosan molecular weight, molecular weight of polymers in the matrix, and pH. The adhesion mechanism relies primarily on the topological entanglement between the chitosan chains and the permeable adherends. To further expand the applicability of the adhesives, adhesion time can be decreased by dehydrating the hydrogel matrix to facilitate rapid chitosan interpenetration and entanglement (>1000 J m−2 in ≤1 min). The unprecedented adhesive properties presented in this study open opportunities for new strategies in the development of non‐covalent tissue adhesives and numerous bioapplications.
Self‐Powered Multifunctional Human–Machine Interfaces for Respiratory Monitoring and Smart System Control
Authors: Pang Yaokun , Chen Shoue , Cao Yunteng , Huang Zhida , Xu Xianchen , Fang Yuhui , (Chase) Cao Changyong 
Published: July 2022

AbstractInnovative human–machine interfaces (HMIs) have attracted increasing attention in the field of system control and assistive devices for disabled people. Conventional HMIs that are designed based on the interaction of physical movements or language communication are not effective or appliable to severely disabled users. Here, a breath‐driven triboelectric sensor is reported consisting of a soft fixator and two circular‐shaped triboelectric nanogenerators (TENGs) for self‐powered respiratory monitoring and smart system control. The sensor device is capable of effectively detecting the breath variation and generates responsive electrical signals based on different breath patterns without affecting the normal respiration. A breathing‐driven HMI system is demonstrated for severely disabled people to control electrical household appliances and shows an intelligent respiration monitoring system for emergence alarm. The new system provides the advantages of high sensitivity, good stability, low cost, and ease of use. This work will not only expand the development of the TENGs in self‐powered sensors, but also opens a new avenue to develop assistive devices for disabled people through innovation of advanced HMIs.
High‐Performance Inverted Tandem OLEDs with the Charge Generation Layer based on MoOx and Ag Doped Planar Heterojunction
Authors: Xu Yachen , Niu Yixiao , Gong Chunliu , Shi Wei , Yang Xuyong , Wei Bin , Wong Wai‐Yeung 
Published: July 2022

AbstractThe morphological and electrical characteristics of a planar‐heterojunction structured charge generation layer (CGL) consisting of MoO3 doped N,N′‐bis‐(1‐naphthalenyl)‐N, N′‐bis‐phenyl‐(1,1′‐biphenyl)‐4,4′‐diamine (NPB) as the p‐type material and Ag‐doped 4,7‐diphenyl‐1,10‐phenanthroline (Bphen) as the n‐type counterpart (NPB:MoO3/Bphen:Ag). A significant charge generation effect of CGL is observed and its mechanism is analyzed. The introduction of CGL can enhance the concentration of the charge carrier and balance the injection of carriers. Inverted tandem organic light‐emitting diodes (OLEDs) with the CGL are fabricated. The inverted tandem OLEDs exhibit excellent optoelectronic performance due to the charge generation effect and the suppression of the high concentration quenching. The maximum current efficiency and external quantum efficiency of the inverted tandem OLED reached 27.91 cd A−1 and 11.18%, respectively, which are 110.95% and 95.79% higher than that of the inverted OLED.
Ultralow Current Switching of Synthetic‐Antiferromagnetic Magnetic Tunnel Junctions Via Electric‐Field Assisted by Spin–Orbit Torque
Authors: Zink Brandon R. , Zhang Delin , Li Hongshi , Benally Onri J. , Lv Yang , Lyu Deyuan , Wang Jian‐Ping 
Published: July 2022

AbstractSpintronic devices, especially electric‐field and spin–orbit torque driven magnetic tunnel junctions (MTJs), are promising candidates to replace the current memory and logic components for satisfying future computing demands. Current spin–orbit torque based MTJ devices with a single free layer and spin Hall channel still face high current density for switching. Here, 150‐nm perpendicular MTJs are designed and fabricated with a synthetic‐antiferromagnetic free layer and a bilayered spin Hall channel. The switching behavior is investigated via combination of forces from electric‐field and spin–orbit torque, where the electric field can modulate the exchange coupling of the synthetic‐antiferromagnetic free layer. Through an assistance of spin–orbit torque, bidirectional switching is obtained with switching current density as low as 3 × 103 A cm−2, which is two orders of magnitude lower than that of the current best reported values. These results suggest that electric‐field switching of synthetic‐antiferromagnetic MTJs could be a promising approach for reducing write current density of spintronic devices.
Sputtered Electrolyte‐Gated Transistor with Modulated Metaplasticity Behaviors
Authors: Fu Yang Ming , Li Hu , Huang Long , Wei Tianye , Hidayati Faricha , Song Aimin 
Published: July 2022

AbstractElectrolyte‐gated transistors have been proposed as promising candidates for neuromorphic applications. Synaptic plasticity behaviors and most recently synaptic metaplasticity or plasticity of plasticity behaviors have been mimicked on electrolyte‐gated transistors. In this work, indium‐gallium‐zinc‐oxide thin‐film transistors gated with sputtered SiO2 electrolytes are fabricated. Both spiking‐width‐dependent and spiking‐height‐dependent metaplasticity behaviors are successfully mimicked. The effects are modulated by the drain voltage bias. A physical model based on the electric‐double‐layer coupling, the RC circuit theory, and the stretched‐exponential diffusion is proposed for the metaplasticity behaviors. The experiment data have been well fitted by the proposed model. Meanwhile, the Bienenstock, Cooper, and Munro learning rule, which describes the threshold‐tunable, spiking‐rate‐dependent plasticity behaviors, is also successfully emulated, providing insight into the synaptic metaplasticity behaviors in electrolyte‐gated synaptic transistors.
Innovative strategies to improve hematopoietic stem cell transplant outcomes in myelofibrosis
Authors: Perram Jacinta , Ross David M. , McLornan Donal , Gowin Krisstina , Kröger Nicolas , Gupta Vikas , Lewis Clinton , Gagelmann Nico , Hamad Nada 
Published: July 2022

AbstractMyelofibrosis (MF) is a clonal myeloproliferative neoplasm characterized by inflammation, marrow fibrosis, and an inherent risk of blastic transformation. Hematopoietic allogeneic stem cell transplant is the only potentially curative therapy for this disease, however, survival gains observed for other transplant indications over the past two decades have not been realized for MF. The role of transplantation may also evolve with the use of novel targeted agents. The chronic inflammatory state associated with MF necessitates pretransplantation assessment of end‐organ function. Applying the transplant methodology employed for other myeloid disorders to patients with MF fails to acknowledge differences in the underlying disease pathophysiology. Limited understanding of the causes of poor transplant outcomes in this cohort has prevented refinement of transplant eligibility criteria in MF. There is increasing evidence of heterogeneity in molecular disease grade, beyond the clinical manifestations which have traditionally guided transplant timing. Exploring the physiological consequences of disease chronicity unique to MF, acknowledging the heterogeneity in disease grade, and using advanced prognostic models, molecular diagnostics and other organ function diagnostic tools, we present an innovative review of strategies with the potential to improve transplant outcomes in this disease. Larger, prospective studies which consider the impact of molecular‐based disease grade are needed for MF transplantation.
Genomic and biochemical analysis of repeatedly observed variants in DBT in individuals with maple syrup urine disease of Central American ancestry
Authors: Billington Charles J. , Chapman Kimberly A. , Leon Eyby , Meltzer Beatrix W. , Berger Seth I. , Olson Matthew , Figler Robert A. , Hoang Steve A. , Wanxing Cui , Wamhoff Brian R. , Collado M. Sol , Cusmano‐Ozog Kristina 
Published: July 2022

AbstractMaple syrup urine disease (MSUD) is an intoxication‐type inherited metabolic disorder in which hyperleucinemia leads to brain swelling and death without treatment. MSUD is caused by branched‐chain alpha‐ketoacid dehydrogenase deficiency due to biallelic loss of the protein products from the genes BCKDHA, BCKDHB, or DBT, while a distinct but related condition is caused by loss of DLD. In this case series, eleven individuals with MSUD caused by two pathogenic variants in DBT are presented. All eleven individuals have a deletion of exon 2 (delEx2, NM_001918.3:c.48_171del); six individuals are homozygous and five individuals are compound heterozygous with a novel missense variant (NM_001918.5:c.916 T > C [p.Ser306Pro]) confirmed to be in trans. Western Blot indicates decreased amount of protein product in delEx2;c.916 T > C liver cells and absence of protein product in delEx2 homozygous hepatocytes. Ultrahigh performance liquid chromatography–tandem mass spectrometry demonstrates an accumulation of branched‐chain amino acids and alpha‐ketoacids in explanted hepatocytes. Individuals with these variants have a neonatal‐onset, non‐thiamine‐responsive, classical form of MSUD. Strikingly, the entire cohort is derived from families who immigrated to the Washington, DC, metro area from Honduras or El Salvador suggesting the possibility of a founder effect.
Tuning the Interlayer Interactions of 2D Covalent Organic Frameworks Enables an Ultrastable Platform for Anhydrous Proton Transport
Authors: Jiang Guoxing , Zou Wenwu , Ou Zhaoyuan , Zhang Longhai , Zhang Weifeng , Wang Xiujun , Song Huiyu , Cui Zhiming , Liang Zhenxing , Du Li 
Published: July 2022

AbstractThe development of effective, stable anhydrous proton‐conductive materials is vital but challenging. Covalent organic frameworks (COFs) are promising platforms for ion and molecule conduction owing to their pre‐designable structures and tailor‐made functionalities. However, their poor chemical stability is due to weak interlayer interactions and intrinsic reversibility of linkages. Herein, we present a strategy for enhancing the interlayer interactions of two‐dimensional COFs via importing planar, rigid triazine units into the center of C3‐symmetric monomers. The developed triazine‐core‐based COF (denoted as TPT‐COF) possesses a well‐defined crystalline structure, ordered nanochannels, and prominent porosity. The proton conductivity was ≈10 times those of non‐triazinyl COFs, even reaching up to 1.27×10−2 S cm−1 at 160 °C. Furthermore, the TPT‐COF exhibited structural ultrastability, making it an effective proton transport platform with remarkable conductivity and long‐term durability.
Suppression of SARS‐CoV‐2 Replication with Stabilized and Click‐Chemistry Modified siRNAs
Authors: Traube Franziska R. , Stern Marcel , Tölke Annika J. , Rudelius Martina , Mejías‐Pérez Ernesto , Raddaoui Nada , Kümmerer Beate M. , Douat Céline , Streshnev Filipp , Albanese Manuel , Wratil Paul R. , Gärtner Yasmin V. , Nainytė Milda , Giorgio Grazia , Michalakis Stylianos , Schneider Sabine , Streeck Hendrik , Müller Markus , Keppler Oliver T. , Carell Thomas 
Published: July 2022

AbstractThe emergence of more transmissible or aggressive variants of SARS‐CoV‐2 requires the development of antiviral medication that is quickly adjustable to evolving viral escape mutations. Here we report the synthesis of chemically stabilized small interfering RNA (siRNA) against SARS‐CoV‐2. The siRNA can be further modified with receptor ligands such as peptides using CuI‐catalysed click‐chemistry. We demonstrate that optimized siRNAs can reduce viral loads and virus‐induced cytotoxicity by up to five orders of magnitude in cell lines challenged with SARS‐CoV‐2. Furthermore, we show that an ACE2‐binding peptide‐conjugated siRNA is able to reduce virus replication and virus‐induced apoptosis in 3D mucociliary lung microtissues. The adjustment of the siRNA sequence allows a rapid adaptation of their antiviral activity against different variants of concern. The ability to conjugate the siRNA via click‐chemistry to receptor ligands facilitates the construction of targeted siRNAs for a flexible antiviral defence strategy.
Die Kernresonanzspektren von Pyridin‐Derivaten
Authors: Brügel W. 
Published: July 2022

AbstractDie Kernresonanzspektren von 154 Pyridinderivaten werden bei 40 und teilweise bei 60 MHz in reiner Form ‐ soweit es sich um Flüssigkeiten handelt ‐ und in Lösung in Dimethylsulfoxyd untersucht. Die Spektren werden dem Spektraltyp gemäß auf chemische Verschiebungswerte und Kopplungskonstanten ausgewertet.Die Kopplungskonstanten erweisen sich als nur wenig von den Substituenten beeinflußt, mit Ausnahme von starken Elektronendonatoren in 3‐Stellung. In den Werten der chemischen Verschiebung spiegeln sich die Elektronendonator‐ bzw. ‐akzeptoreigenschaften der Substituenten wider, wobei allerdings auch noch Anisotropieeffekte berücksichtigt werden müssen. Eine Sonderstellung nehmen 2‐ bzw. 6‐Hydroxypyridine ein, was auf ihre Pyridon‐Konstitution zurückzuführen ist.
On‐line untargeted metabolomics monitoring of an Escherichia coli succinate fermentation process
Authors: Cortada‐Garcia Joan , Haggarty Jennifer , Moses Tessa , Daly Rónán , Arnold Susan Alison , Burgess Karl 
Published: July 2022

AbstractThe real‐time monitoring of metabolites (RTMet) is instrumental for the industrial production of biobased fermentation products. This study shows the first application of untargeted on‐line metabolomics for the monitoring of undiluted fermentation broth samples taken automatically from a 5 L bioreactor every 5 min via flow injection mass spectrometry. The travel time from the bioreactor to the mass spectrometer was 30 s. Using mass spectrometry allows, on the one hand, the direct monitoring of targeted key process compounds of interest and, on the other hand, provides information on hundreds of additional untargeted compounds without requiring previous calibration data. In this study, this technology was applied in an Escherichia coli succinate fermentation process and 886 different m/z signals were monitored, including key process compounds (glucose, succinate, and pyruvate), potential biomarkers of biomass formation such as (R)‐2,3‐dihydroxy‐isovalerate and (R)‐2,3‐dihydroxy‐3‐methylpentanoate and compounds from the pentose phosphate pathway and nucleotide metabolism, among others. The main advantage of the RTMet technology is that it allows the monitoring of hundreds of signals without the requirement of developing partial least squares regression models, making it a perfect tool for bioprocess monitoring and for testing many different strains and process conditions for bioprocess development.
“I wasn’t feeling like I belonged in my skin”: How self‐identified gay men in theUKexperience unhelpful incidents in talking therapy1
Authors: Televantos Mike , Strauss Susan Maise 
Published: July 2022

AbstractBackgroundContemporary psychological research and practice in Western Societies oppose pathologising perspectives about same‐sex attraction. Nonetheless, recent research indicates gay men may still experience unhelpful incidents in talking therapy in relation to their sexual/affectional orientation. Research focusing on how self‐identified gay men (SIGM) experience these unhelpful incidents, however, remains sparse.AimThe objective of the present study is to offer insight into the phenomenon of unhelpful experiences of SIGM clients in relation to their sexual/affectional orientation.MethodThe data were collected through individual, semi‐structured interviews of six SIGM (aged 25–57), describing how they currently experience these unhelpful incidents. This study employed Interpretative Phenomenological Analysis (IPA) to capture the lived experiences and sense‐making of the participants.FindingsThe following three Master Themes were identified: (1) Making Sense of Disconnection, (2) A Rejecting Therapy for a Gay Individual, and (3) Understanding the Impact of Unhelpful Incidents Outside Therapy. The unhelpful experiences of SIGM clients appeared to be largely coloured by the sense of disconnection they felt from their therapists. These followed an experience of therapy that they felt did not acknowledge or embrace their individual gay identity. Participants relayed how these experiences impacted their lives outside therapy. Despite the significant and lasting negative impact, however, all imparted a sense of managing to move on to some extent.ConclusionsThe present research could encourage therapists and researchers to continue pursuing and embracing helpful ways of working therapeutically with SIGM and other sexual, gender and intersecting identities.
Research on occlusion block face recognition based on feature point location
Authors: Shi Jianguo , Xiu Yu , Tang Ganyi 
Published: July 2022

AbstractAiming at improving the poor face recognition accuracy under occlusion, a multipose block occlusion face recognition method based on feature point location is proposed. Face segmentation is carried out according to the location results of face feature points and occlusion areas. The local features of each face block are extracted by deep convolution neural network. The dynamic adaptive weighting method is used to give different weights to the face block information, and the occluded face recognition is completed according to the results of face segmentation, which effectively reduces the impact of pose change and occlusion on face recognition. The experiment is analyzed from two aspects: frontal occlusion and multipose face occlusion. The results show that fewer blocks in the frontal occlusion experiment are conducive to maintaining good local integrity and relatively good recognition performance; When the proportion of frontal occlusion reaches 50%, the recognition rate of our algorithm can still be up to 92.68%, which is significantly better than other algorithms.