bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coating (Coating to Optimize Aneurysm Treatment in the New Flow Diverter Generation) study. The first randomized controlled trial evaluating a coated flow diverter (p64 MW HPC): study design
Authors: Pierot Laurent , Lamin Saleh , Barreau Xavier , Berlis Ansgar , Ciceri Elisa , Cohen José E , Costalat Vincent , Eker Omer F , Henkes Hans , Holtmannspötter Markus , Januel Anne-Christine , Keston Peter , Klisch Joachim , Psychogios Marios-Nikos , Valvassori Luca , Cognard Christophe , Spelle Laurent 
Published: May 2022

BackgroundDue to its high efficacy, flow diversion is increasingly used in the management of unruptured and recanalized aneurysms. Because of the need for perioperative dual antiplatelet treatment (DAPT), flow diversion is not indicated for the treatment of ruptured aneurysms. To overcome this major limitation, surface modification—‘coating’—of flow diverters has been developed to reduce platelet aggregation on the implanted device, reduce thromboembolic complications, and facilitate the use of coated flow diverter treatment in patients with single antiplatelet treatment (SAPT). COATING (Coating to Optimize Aneurysm Treatment in the New Flow Diverter Generation) is a prospective, randomized, multicenter trial that aims to determine whether the use of the coated flow diverter p64 MW HPC under SAPT is non-inferior (or even superior) to the use of the bare flow diverter p64 MW under DAPT in relation to thromboembolic and hemorrhagic complications.MethodsPatients with unruptured or recanalized aneurysms for which endovascular treatment with a flow diverter is indicated will be enrolled and randomly assigned on a 1:1 ratio to one of two treatment groups: p64 MW HPC with SAPT or p64 MW with DAPT.ResultsThe primary endpoint is the number of diffusion-weighted imaging lesions visualized via MRI assessed within 48 hours (±24 hours) of the index procedure. Secondary primary endpoints are comparing safety and efficacy in both arms.ConclusionsThis randomized controlled trial is the first to directly compare safety and efficacy of coated flow diverters under SAPT with bare flow diverters under DAPT.Trial registration numberhttp://clinicaltrials.gov/-NCT04870047.
Alternating current conductivity and superconducting properties of a holographic effective model with broken translations
Authors: Liu Yan , Wang Xi-Jing , Wu Jian-Pin , Zhang Xin 
Published: May 2022

AbstractWe construct a holographic effective superconducting theory by considering a special gauge-axion coupling. In the normal state, we observe that a peak emerges in the mid-IR in the AC conductivity for certain strength of broken translations and the gauge-axion coupling. It is attributed to the emergence of pseudo-Goldstone mode due to the competition of spontaneous symmetry breaking (SSB) and the explicit symmetry breaking (ESB). However, when the ESB dominates over the SSB, the peak disappears. In the superconducting phase, this gauge-axion coupling also plays a key role leading to a more evident gap at the low frequency conductivity. In addition, we also study the combined effects of the strength of broken translations and various couplings among the gauge field, axion fields and the complex scalar field.
Accuracy of one-dimensional approximation in neutron star quasi-normal modes
Authors: Sotani Hajime 
Published: May 2022

AbstractSince the eigenfrequency of gravitational waves from cold neutron stars becomes a complex number, where the real and imaginary parts respectively correspond to an oscillation frequency and damping rate, one has to somehow solve the eigenvalue problem concerning the eigenvalue in two-dimensional parameter space. To avoid this bother, one sometimes adopts an approximation, where the eigenvalue is in one-dimensional parameter space. In this study, first, we show the accuracy of the zero-damping approximation, which is one of the one-dimensional approximations, for the fundamental and 1st pressure modes. But, this approximation is not applicable to the spacetime mode, because the damping rate of the spacetime mode is generally comparable to the oscillation frequency. Nevertheless, we find the empirical relation for the ratio of the imaginary part to the real part of the eigenfrequency, which is expressed as a function of the steller compactness almost independently of the adopted equations of state for neutron star matter. Adopting this empirical relation, one can express the eigenfrequency in terms of just the real part, i.e., the problem to solve becomes an eigenvalue problem with a one-dimensional eigenvalue. Then, we find that the frequencies are estimated with good accuracy even with such approximations even for the 1st spacetime mode.
Subaerial volcaniclastic deposits – influences of initiation mechanisms and transport behaviour on characteristics and distributions
Authors: Major Jon J. 
Published: May 2022

Abstract
Subaerial volcaniclastic deposits are produced principally by volcanic debris avalanches, pyroclastic density currents, lahars, and tephra falls. Those deposits have widely ranging geomorphic and sedimentologic characteristics; they can mantle, modify, or create new topography, and their emplacement and subsequent reworking can have an outsized impact on the geomorphic and sedimentologic responses of watersheds surrounding, and channels draining, volcanoes. Volcaniclastic deposits provide a wealth of information about eruptive histories, volcanic processes, and landscape responses to eruptions. The volcanic processes that produce these deposits, and consequently the character and sedimentary structures of the deposits themselves, are influenced by initiation mechanism. Deposit preservation is affected by deposit magnitude, texture, and composition, depositional environment, and climate regime. Innovative analyses of deposits from several modern eruptions and advancements in physical and numerical modelling have vastly improved our understanding of volcanic processes, interpretations of eruptive histories, and recognition of the hazards posed by volcanic eruptions. This contribution highlights and summarizes major advances that have occurred in the past few decades in understanding of volcaniclastic deposits and linkages with volcanic processes.
Machine Learning–based Modeling and Prediction of the Intrinsic Relationship between Human Emotion and Music
Authors: Su Jun , Zhou Peng 
Published: May 2022

Human emotion is one of the most complex psychophysiological phenomena and has been reported to be affected significantly by music listening. It is supposed that there is an intrinsic relationship between human emotion and music, which can be modeled and predicted quantitatively in a supervised manner. Here, a heuristic clustering analysis is carried out on large-scale free music archive to derive a genre-diverse music library, to which the emotional response of participants is measured using a standard protocol, consequently resulting in a systematic emotion-to-music profile. Eight machine learning methods are employed to statistically correlate the basic sound features of music audio tracks in the library with the measured emotional response of tested people to the music tracks in a training set and to blindly predict the emotional response from sound features in a test set.
This study found that nonlinear methods are more robust and predictable but considerably more time-consuming than linear approaches. The neural networks have strong internal fittability but are associated with a significant overfitting issue. The support vector machine and Gaussian process exhibit both high internal stability and satisfactory external predictability in all used methods; they are considered as promising tools to model, predict, and explain the intrinsic relationship between human emotion and music. The psychological basis and perceptional implication underlying the built machine learning models are also discussed to find out the key music factors that affect human emotion.
Selinexor Combined with Ibrutinib Demonstrates Tolerability and Safety in Advanced B-Cell Malignancies: A Phase I Study
Authors: Stephens Deborah M. , Huang Ying , Ruppert Amy S. , Walker Janek S. , Canfield Daniel , Cempre Casey B. , Fu Qiang , Baker Sharyn , Hu Boyu , Shah Harsh , Vadeboncoeur Renee , Rogers Kerry A. , Bhat Seema , Jaglowski Samantha M. , Lockman Hank , Lapalombella Rosa , Byrd John C. , Woyach Jennifer A. 
Published: May 2022

Abstract

Purpose:
Dual blockade of Bruton's tyrosine kinase with ibrutinib and selinexor has potential to deepen responses for patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).

Patients and Methods:
In this phase I study (clinicaltrials.gov: NCT02303392), adult patients with CLL/NHL, relapsed/refractory to ≥1 prior therapy were enrolled. Patients received weekly oral selinexor and daily oral ibrutinib in 28-day cycles until progression or intolerance. Primary objective was to determine MTD.

Results:
Included patients had CLL (n = 16) or NHL (n = 18; 9 Richter transformation, 6 diffuse large B-cell lymphoma, and 3 mantle cell lymphoma). Median prior therapies were 4 (range = 1–14) and 59% previously received ibrutinib. The established MTD was 40 mg of selinexor (days 1, 8, 15) and 420 mg daily ibrutinib. Common nonhematologic adverse events were fatigue (56%), nausea (53%), anorexia (41%), and diarrhea (41%) and were mostly low grade. Overall response rate was 32%. An additional 47% achieved stable disease (SD), some prolonged (up to 36 months). Median progression-free survival for patients with CLL and NHL was 8.9 [95% confidence interval (CI), 3.9–16.1] and 2.7 (95% CI, 0.7–5.4) months, respectively. For patients with CLL who did not receive prior ibrutinib, only 20% (1/5) progressed. Estimated 2-year overall survival was 73.7% (95% CI, 44.1–89.2) and 27.8% (95% CI, 10.1–48.9) for patients with CLL and NHL, respectively.

Conclusions:
The selinexor and ibrutinib combination has demonstrated tolerability in patients with relapsed/refractory CLL/NHL. Responses were durable. Notable responses were seen in patients with CLL with minimal prior therapy. Future study of this combination will focus on efforts to deepen remissions in patients with CLL receiving ibrutinib therapy.
Trials, Tribunals, and Opportunities for Lung Cancer KRASG12C Brain Metastases
Authors: Kommalapati Anuhya , Mansfield Aaron S. 
Published: May 2022

Summary
The activity of KRAS inhibitors against brain metastases is relatively unexplored. The recent work on preclinical models and preliminary data from the ongoing KRYSTAL-1 phase Ib clinical trial support the potential of adagrasib (MRTX849) to penetrate the central nervous system and provide control of KRASG12C brain metastases.
See related article by Sabari et al., p. 3318
Fault tolerant nine-level inverter topology for solar water pumping applications
Authors: Rao Mucherla Narasimha , Karthick Nagaraj , Rao Airineni Madhukar 
Published: May 2022

<span>Diminished voltage pressure and occasional-general harmonic distortion are the essential causes for such a ways and extensive usage of multi-level inverters (MLIs) in numerous industrial applications. Nonetheless, unwavering quality is one of the significant worries of MLIs as it utilizes countless switches as contrasted to 2-level inverters. Here, a fault tolerant 9-level inverter setup for the use of photovoltaic (PV) system-water pumping applications is suggested. This fault tolerant 9-level inverter is accomplished by combining a 2-level inverter, a 3-level fault tolerant inverter alongside switches with bidirectional ability. The setup is taken care of with four PV fed sources. The arrangement suggested shows the behavior towards switch fault in at least one inverter legs under open circuit conditions. On account of source failure, it could use the better hotspot for introducing continuous power to the water pumping motor. Meanwhile, the suggested fault-tolerant inverter works as seven-level inverter. The activity related to proposed inverter in the course of various failure modes is mentioned and simulated the usage of MATLAB/Simulink.</span>
A new compact grounded coplanar waveguide slotted multiband planar antenna for radio frequency identification data applications
Authors: Dakir Rachid , Mouhsen Ahmed 
Published: May 2022

<p><span>This research presents the development and conception of a new compact grounded coplanar waveguide fed slotted rectangular planar antenna with a multi-frequency band for <a name="_Hlk94076774"></a>radio frequency identification data (RFID) reader applications which is based on the antenna mono-band frequency to use for a various applications RFID to support a different operating range. The optimized of the final prototype designing operates a multiple frequency bands ranging from 0.7-1.1 GHz, 2.2-2.5 GHz and 5.4-6 GHz for 0.9/2.4 GHz and 5.8 GHz RFID operation bands which is adapted from ultra-high frequency band (0.9 GHz) to microwave frequency band (2.4-5.8 GHz) RFID systems. This antenna is implemented and printed on a FR4 substrate with a size of 30×50×1.6 mm<sup>3</sup>. The novel prototype includes of a radiator rectangular patch with a symmetrical slot and a U-slot with I-stub on ground plan. The principles parameters of the antenna have been studied optimized and miniaturized by using a two simulators CST Microwave Studio and advanced design system (ADS) to validate the simulation results before the planar antenna realization. The final structure is achieved and validated of the results measurement. Experimental results show that the proposed antenna with a small size has good and stable radiation and thus promising for a various RFID applications.</span></p>
A novel design of wide and multi-bands 2×2 multiple-input multiple-output antenna for 5G mm-wave applications
Authors: Shakir Muttair Karrar , Zuhair Ghazi Zahid Ali , Ahmed Shareef Oras , Qasim Kamil Ahmed Mohammed , Farhan Mosleh Mahmood 
Published: May 2022

In this paper, we present a new design for a multiple-input multiple-output (MIMO) antenna with four ports operating in wide and multi-millimeter-wave (Mm-Wave) bands for various 5G applications (including the internet of things (IoT), communication devices, and smartphones). The antenna is designed in a rectangular zigzag shape with slots to make the antenna operate at different frequencies. For this, the antenna operates at multiple frequencies from 38 to 62 GHz, so it supports all advanced wireless communication applications. The most important characteristic of the design is its small size and compact structure compared to designs presented by researchers in previous literature so<em> </em>the antenna dimensions for four elements are 29×49 mm<sup>2</sup>. The antenna performance based on the results obtained from CST Studio Suite is good since the reflection coefficients of the antenna resonate at six main frequencies are 39.128 GHz, 42.992 GHz, 47.384 GHz, 51.536 GHz, 55.472 GHz, and 59.288 GHz. In addition, the isolation value between all antenna elements is ≤30 dB and the diversity gain value for all frequencies is 10 dB. Moreover, a very small value was obtained for the envelope correlation coefficient (ECC) is &lt;4.0576×10<sup>−11</sup>. Finally, the results indicate a favorable design and potential competitor for all 5G MIMO Mm-Wave applications.<br /><em></em>
Prevalence of Housing Insecurity in Survivors of Traumatic Injury
Authors: Vera Luis , Reed Kendal Kamaria , Rose Elizabeth , DeYampert LaShondra , Woodard Jessica , Cortes Juliana , Henry Antonio , Thompson Alexis Nicole , Williams Keneeshia Nicole , Blount Quinton , Castater Christine , Schenker Mara , Smith Randi N. 
Published: May 2022

Background Almost 20% of the US population are housing insecure (HI) due to inadequate living conditions, imbalanced costs to income, nonsustainable shelter, or overcrowding. Housing insecure and physical trauma share similar risk factors, but their direct association is not well elucidated. The objective of our study was to determine the prevalence of HI in survivors of traumatic injury. Methods We conducted a prospective cohort study at an urban, level 1 trauma center. A survey on social determinants of health was administered to adult patients, and demographic, injury specifics, and clinical outcomes data were collected. HI was defined by affirmative answers to questions related to history of homelessness or concern about sustainable shelter. The cohort was stratified by HI; groups were compared using the Mann-Whitney U and Fisher exact tests, as appropriate. Results Of 116 study participants, four were excluded due to missing data. Of the 112, 42 (37.8%) reported HI and most were black (69%) males (73.8%). There were no demographic differences between groups. Conversely, HI patients had a higher rate of penetrating traumatic injury (34.1% vs 14.5%, P-value = .03) and were significantly less educated compared to secure participants ( P-value = .03) [no degree (26.2% vs 10.3%), high school degrees (21.4% vs 41.2%)] with concomitant illicit drug use (63.4% vs 27.9%, P < .001), and history of addiction (52.4% vs 7.2%, P < .001). Conclusion HI far exceeds national averages in our cohort. Although difficult to ascertain a cause-effect relationship, HI may be a modifiable risk factor for trauma that negatively influences outcomes.
Conflict of Interest Disclosure Among the Highest Earning Physicians Receiving Compensation From Vascular Device Companies
Authors: Al-Khouja Fares , Nyam Amanda , Sheehan Brian , Sullivan Brittany , Kabutey Nii-Kabu , Stamos Michael J. , Pigazzi Alessio , Jafari Mehraneh D. 
Published: May 2022

Objective To characterize the association between payments made by vascular device companies to clinicians, and the conflict of interest (COI) declarations on relevant publications. Summary Background Data Close association between medical device companies and clinicians is essential in the advancement of surgical technology. When evaluating the efficacy of novel equipment, identification of these relationships can minimize the risk of bias in relevant studies. Methods Using the Open Payments Database (OPD), the 10 highest compensated clinicians from 10 vascular device companies were identified. In the population based bibliometric analysis, general payments, number of payments, h-index, and academic rank were identified. PubMed and Scopus were queried to identify author publications. Relevance to payment received and COI disclosures were identified for each article. Results The physicians identified earned $33,442,266.74 with a median of $92,500 in 2017. The authors published an average of 6.46+/−9.08 articles in 2018. Relevant COI was identified in 74%. In 50.5% of the relevant publications was a COI declared. The median h index of authors was 18+/−23. Community based physicians had a higher rate of COI disclosure (65.6%) compared to academic physicians (47.6%) (P = .008). Low h-index authors had a higher rate of COI declaration (71.4%) compared to high h-index (43.6%) (P = .001). Conclusion A high degree of inconsistency was found between self-declared COI and relevant articles published by the highest compensated physicians. We propose a policy of full disclosure and the addition of a link to each author’s OPD page on all publications to increase access to potential COI.
Impact of Giving Patients Your Personal Phone Number in Otolaryngology—Head & Neck Surgery
Authors: Adams Matthew D. , Wong Jeff , Gadre Arun , Greene Joseph Scott , Milligan Donna , Paknezhad Hassan , Purdy Nicholas , Rager Jennifer , Wertz Aileen , Whitenight Season , Haugen Thorsen W. 
Published: May 2022

Objective: Patient-provider communication is a major barrier to care, with some providers giving their personal phone number (PPN) to patients for increased accessibility. We investigated participant utilization of provider’s PPN, its effect on participant satisfaction, provider’s ability to predict abuse of this practice, and evolving provider perceptions. Study Design: Prospective, randomized study. Setting: Single institution, tertiary referral center. Methods: During a 2-week period, otolaryngology patients were randomized to either receive their provider’s PPN or not. Providers predicted the likelihood of abuse. All calls/texts were documented for 4 weeks. At the study’s conclusion, participants were surveyed using Press Ganey metrics. Providers were surveyed before and after to assess their likelihood of providing patients with their PPN and its impact on work demands. Results: Of the 507 participants enrolled, 266 were randomized to the phone number group (+PN). Of 44 calls/texts from 24 participants, 8 were considered inappropriate. Ten participants were predicted to abuse the PPN, but only one was accurately identified. Participants in the +PN group had a greater mean composite satisfaction score than the control group (4.8 vs 4.3; Welch’s t-test, P < .0011). At the conclusion of the study, providers were more likely to share their PPN (Wilcoxon signed-rank test, P < .0313), and their perceived impact of this practice on workload was lower (Wilcoxon signed-rank test, P < .0469). Conclusion: This study demonstrates low patient utilization of provider PPNs, and poor provider predictive ability of patient abuse. Receipt of provider’s PPN was associated with improved patient satisfaction.
Method of voltage setting for power battery simulator using successive nearest-neighbor interpolation
Authors: Yi Jiliang , Tan Huabing , Zhang Jin , Li Zhongqi 
Published: May 2022

The power battery simulator is important equipment in new energy vehicle test platform and other industrial fields, and the battery model is the key to emulate the battery characteristics accurately. A novel method of given voltage for the power battery simulator is proposed in the paper. According to the state of charge (SOC) of the power battery, three sub-tables with different resolutions are established corresponding to the initial, stationary, and final stage of SOC. To ensure the accuracy of a given voltage under small data capacity, a successive nearest-neighbor interpolation (SNNI) algorithm is proposed for processing battery model data and the iterative calculation is carried out for the data obtained by looking up the table until it approaches the required value. Simulations and experiments are done on various capacity data tables, which are obtained by employed different sampling ratios to reduce the data capacity, and the influence of iteration number selection on the accuracy of the algorithm is discussed. The results show that, after 4–5 iterations, the given voltage accuracy is controlled within 0.03 V by the SNNI algorithm with only 1.6% capacity of the standard model table, which is greatly improved compared with the traditional method, and the feasibility is verified by executing the proposed algorism in a DSP system.