bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers and facilitators in the delivery of a proportionate universal parenting program model (E-SEE Steps) in community family services
Authors: Berry Vashti , Mitchell Siobhan B. , Blower Sarah , Whittaker Karen , Wilkinson Kath , McGilloway Sinead , Mason-Jones Amanda , Carr Rachel Margaret , Bywater Tracey 
Published: June 2022

BackgroundA proportionate universal (PU) approach to early years’ service provision has been advocated to improve children’s health and development and to reduce health inequality, by ensuring that services provide timely and high-quality parenting support commensurate with need. Process-oriented research is critical to examine the factors that contribute to, or hinder, the effective delivery/implementation of such a model in community-based family services. This study aimed to assess the delivery, acceptability and feasibility of a new PU parenting intervention model (called E-SEE Steps), using the Incredible Years® (IY) parent program, when delivered by trained health/family service staff in three “steps”—one universal step (the IY Babies Book), and two targeted steps (group-based IY Infant and Toddler programs).MethodsAn embedded mixed-methods process evaluation within a pragmatic parallel two-arm, assessor blinded, randomized controlled trial was conducted in community services in four local authorities in England. The process evaluation used qualitative data gathered via interviews and focus groups with intervention arm parents who were offered the targeted steps (n = 29), practitioners (n = 50), service managers (n = 7) and IY program mentors (n = 3). This was supplemented by quantitative data collected using group leader pre-training (n = 50) and post-delivery (n = 39) questionnaires, and research notes of service design decisions.ResultsThe E-SEE Steps model was acceptable to most parents, particularly when it was accompanied by engagement strategies that supported attendance, such as providing childcare. Practitioners also highlighted the positive development opportunities provided by the IY training and supervision. However, participant views did not support the provision of the IY Babies book as a standalone universal component, and there were barriers to eligible parents—particularly those with low mood—taking up the targeted programs. Service providers struggled to align the PU model with their commissioned service contracts and with their staff capacity to engage appropriate parents, including tackling common barriers to attendance.ConclusionsDespite general enthusiasm and support for delivering high-quality parenting programs in community services in the England, several barriers exist to successfully delivering IY in a proportionate universal model within current services/systems.
NADPH-oxidase 4 gene over-expression in peripheral blood lymphocytes of the schizophrenia patients
Authors: Ershova Elizaveta S. , Shmarina Galina V. , Martynov Andrey V. , Zakharova Natalia V. , Veiko Roman V. , Umriukhin Pavel E. , Kostyuk George P. , Kutsev Sergey I. , Veiko Natalia N. , Kostyuk Svetlana V. 
Published: June 2022

Introduction
Increased systemic oxidative stress is common in schizophrenia (SZ) patients. NADPH-oxidase 4 (NOX4) is the cell oxidoreductase, catalyzing the hydrogen peroxide formation. Presumably, NOX4 is the main oxidative stress factor in a number of diseases such as cardiovascular diseases and cancer. We hypothesized that NOX4 may be involved in the oxidative stress development caused by the disease in the schizophrenic patients’ peripheral blood lymphocytes (PBL).

Materials and methods
The SZ group included 100 patients (68 men and 32 women aged 28 ± 11 years). The control group included 60 volunteers (35 men and 25 women aged 25 ± 12 years). Flow cytometry analysis (FCA) was used for DNA damage markers (8-oxodG, ɣH2AX), pro- and antiapoptotic proteins (BAX1 and BCL2) and the master-regulator of anti-oxidant response NRF2 detection in the lymphocytes of the untreated SZ patients (N = 100) and the healthy control (HC, N = 60). FCA and RT-qPCR were used for NOX4 and RNANOX4 detection in the lymphocytes. RT-qPCR was used for mtDNA quantitation in peripheral blood mononuclear cells. Cell-free DNA concentration was determined in blood plasma fluorimetrically.

Results
8-oxodG, NOX4, and BCL2 levels in the PBL in the SZ group were higher than those in the HC group (p < 0.001). ɣH2AX protein level was increased in the subgroup with high 8-oxodG (p<0.02) levels and decreased in the subgroup with low 8-oxodG (p <0.0001) levels. A positive correlation was found between 8-oxodG, ɣH2AX and BAX1 levels in the SZ group (p <10−6). NOX4 level in lymphocytes did not depend on the DNA damage markers values and BAX1 and BCL2 proteins levels. In 15% of PBL of the HC group a small cellular subfraction was found (5–12% of the total lymphocyte pool) with high DNA damage level and elevated BAX1 protein level. The number of such cells was maximal in PBL samples with low NOX4 protein levels.

Conclusion
Significant NOX4 gene expression was found a in SZ patients’ lymphocytes, but the corresponding protein is probably not a cause of the DNA damage.
Potential clinical relevance of cardiac magnetic resonance to diagnose cardiac light chain amyloidosis
Authors: Dohy Zsofia , Szabo Liliana , Pozsonyi Zoltan , Csecs Ibolya , Toth Attila , Suhai Ferenc Imre , Czimbalmos Csilla , Szucs Andrea , Kiss Anna Reka , Becker David , Merkely Bela , Vago Hajnalka 
Published: June 2022

Background
While patients with cardiac transthyretin amyloidosis are easily diagnosed with bone scintigraphy, the detection of cardiac light chain (AL) amyloidosis is challenging. Cardiac magnetic resonance (CMR) analyses play an essential role in the differential diagnosis of cardiomyopathies; however, limited data are available from cardiac AL-Amyloidosis. Hence, the purpose of the present study was to analyze the potential role of CMR in the detection of cardiac AL-amyloidosis.

Methods
We included 35 patients with proved cardiac AL-amyloidosis and two control groups constituted by 330 patients with hypertrophic cardiomyopathy (HCM) and 70 patients with arterial hypertension (HT), who underwent CMR examination. The phenotype and degree of left ventricular (LV) hypertrophy and the amount and pattern of late gadolinium enhancement (LGE) were evaluated. In addition, global and regional LV strain parameters were also analyzed using feature-tracking techniques. Sensitivity and specificity of several CMR parameters were analyzed in diagnosing cardiac AL-amyloidosis.

Results
The sensitivity and specificity of diffuse septal subendocardial LGE in diagnosing cardiac AL-amyloidosis was 88% and 100%, respectively. Likewise, the sensitivity and specificity of septal myocardial nulling prior to blood pool was 71% and 100%, respectively. In addition, a LV end-diastolic septal wall thickness ≥ 15 mm had an optimal diagnostic performance to differentiate cardiac AL-amyloidosis from HT (sensitivity 91%, specificity 89%). On the other hand, a reduced global LV longitudinal strain (< 15%) plus apical sparing (apex-to-base longitudinal strain > 2) had a very low sensitivity (6%) in detecting AL-Amyloidosis, but with very high specificity (100%).

Conclusions
The findings from this study suggest that CMR could have an optimal diagnostic performance in the diagnosis of cardiac AL-amyloidosis. Hence, further larger studies are warranted to validate the findings from this study.
GIS-based landslide susceptibility mapping using frequency ratio and index of entropy models for She County of Anhui Province, China
Authors: Liu Yu , Yuan Anying , Bai Zhigang , Zhu Jingzhong 
Published: June 2022

Abstract
Landslides caused countless economic and casualty losses in China, especially in mountainous and hilly areas. Landslide susceptibility mapping is an important approach and tool for landslide disaster prevention and control. This study presents a landslide susceptibility assessment using frequency ratio (FR) and index of entropy (IOE) models within a geographical information system for She County in the mountainous region of South Anhui, China. First, the landslide locations were ascertained in the study area using historical landslide records, aerial photographs, and multiple field surveys. In all, 502 landslides were identified and randomly divided into two groups as training (70%) and validation (30%) datasets. Additionally, the landslide-influencing factors, including slope angle, slope aspect, curvature, landform, lithology, distance to faults, distance to roads, distance to rivers, rainfall, and normalized difference vegetation index, were selected and their relative importance and weights were determined by FR and IOE models. The results show that the very high and high susceptibility classes cover nearly 50% of the study area. Finally, the comprehensive performance of the two models was validated and compared using receiver operating characteristic curves. The results demonstrated that the IOE model with the area under the curve (AUC) of 0.802, which is slightly better in prediction than the FR model (AUC = 0.786). The interpretation of the susceptibility map indicated that landform, slope degree, and distance to rivers plays a major role in landslide occurrence and distribution. The research results can be used for preliminary land use planning and hazard mitigation purposes.
Collusion, Shading, and Optimal Organization Design
Authors: Suzuki Yutaka 
Published: June 2022

Abstract
We introduce a behavioral contract theory idea, “shading” (Hart and Moore (2008). “Contracts as Reference Points.” Quarterly Journal of Economics 123 (1): 1–48)) as a component of ex-post haggling (addressed by Coase (1937. “The Nature of the Firm.” Economica 4 (16): 386–405) and Williamson (1975. Markets and Hierarchies: Analysis and Antitrust Implications. New York: Free Press)) into the collusion model à la Tirole (1986. “Hierarchies and Bureaucracies: On the Role of Collusion in Organizations.” Journal of Law, Economics, and Organization 2: 181–214, 1992. “Collusion and the Theory of Organizations.” In Advances in Economic Theory: The Sixth World Congress, edited by J. J. Laffont. Cambridge: Cambridge University Press), thereby constructing a new model of hierarchical organization. By integrating the two ideas, i.e. collusion and shading, we enrich the existing collusion model, thereby obtaining a new result for Collusion-proof versus Equilibrium Collusion. The basic idea is that the increase in shading pressure strengthens the incentive for collusion, thereby making it difficult to implement collusion-proof incentive schemes, which leads to the Equilibrium Collusion. In addition, we also provide a micro-foundation for ex-post haggling costs, where we view rent-seeking associated with collusive behavior and ex-post haggling generated from aggrievement and shading as the two sources of the costs. This model is used to examine the optimal organizational design problem as an optimal response to the trade-off between gross total surplus and ex-post haggling costs, and to take a step further the idea of efficient organization design (Milgrom (1988. “Employment Contracts, Influence Activities and Efficient Organization Design.” Journal of Political Economy 96: 42–60)). We believe that our model could help provide a deep understanding of resource allocation and decision processes in hierarchical organizations.
Pseudo-free families and cryptographic primitives
Authors: Anokhin Mikhail 
Published: June 2022

Abstract
In this article, we study the connections between pseudo-free families of computational

Ω

\Omega

-algebras (in appropriate varieties of

Ω

\Omega

-algebras for suitable finite sets

Ω

\Omega

of finitary operation symbols) and certain standard cryptographic primitives. We restrict ourselves to families

(

H

d

∣

d
∈
D

)

\left({H}_{d}\hspace{0.33em}| \hspace{0.33em}d\in D)

of computational

Ω

\Omega

-algebras (where

D
⊆

{

0
,
1

}

∗

D\subseteq {\left\{0,1\right\}}^{\ast }

) such that for every

d
∈
D

d\in D

, each element of

H

d

{H}_{d}

is represented by a unique bit string of the length polynomial in the length of

d

d

. Very loosely speaking, our main results are as follows: (i) pseudo-free families of computational mono-unary algebras with one to one fundamental operation (in the variety of all mono-unary algebras) exist if and only if one-way families of permutations exist; (ii) for any

m
≥
2

m\ge 2

, pseudo-free families of computational

m

m

-unary algebras with one to one fundamental operations (in the variety of all

m

m

-unary algebras) exist if and only if claw resistant families of

m

m

-tuples of permutations exist; (iii) for a certain

Ω

\Omega

and a certain variety

V

{\mathfrak{V}}

of

Ω

\Omega

-algebras, the existence of pseudo-free families of computational

Ω

\Omega

-algebras in

V

{\mathfrak{V}}

implies the existence of families of trapdoor permutations.
Corythucha ciliata (Say, 1832) – Pest of Plane Trees (Platanus spp.)
Authors: FLORIAN Teodora , POPUŢA Diana , BUNESCU Horia 
Published: June 2022

The research aimed the study of an invasive species that has recently appeared in our country, Corythucha ciliata Say (plane tiger or lacy plane bedbug) (Hemiptera, Tingidae). Knowing this pest is very important in order to control it, in order to keep the appearance of the parks pleasant and clean. The insect is an aggressive pest of plane trees (Platanus spp.), which harms their leaves, leading to premature defoliation. The aims of this research were: identifying and monitoring of Corythucha ciliata Say populations; observations on the host plants in the analyzed space; tracking the biological cycle of the species Corythucha ciliata Say and the extent of pest. Following research conducted in 2020-2021, the invasive species Corythucha ciliata Say, was identified in 4 locations in Transylvania, on two species of plane trees, Platanus occidentalis Linné and Platanus x acerifolia Willdenow. In the ecological conditions of Cluj-Napoca (Cluj County), the numerical density of the pest on the plane leaves was of maximum 30 adults/leaf and 63 larvae/leaf. Concerning the biological cycle, it was found that, in the temperate-continental climate of Cluj-Napoca, the species has 2 generations per year.
Risk Factors for Obesity and Overweight in Children and Adolescents from Romania
Authors: PRINCIPAL Admin , NEGRUT Gabriela-Alexandra , AVRAM Calin , RACHITA Anca , RUTA Florina Daniela 
Published: June 2022

The fact that more and more people are suffering from obesity and that this condition is more and more common among children is an alarm signal and some measures must be taken in this direction. Nowadays, the most incriminating factor responsible for the development of childhood obesity is the excessive consumption of fast food, sweets and juices, as at the market there is a wide range and easily accessible. This study aims to evaluate the association between frequent consumption of fast food and other lifestyle factors with the presence of obesity and overweight in children of different ages in Romania. Applying a questionnaire with 31 questions we collected data from 328 people, 170 boys and 158 girls, residing in Romania. The analysis of the data collected showed a higher number of overweight children, compared to the number of mothers who consider that their children are overweight, for this we identified the factors with potential obesity and we looked for the associations between the lifestyle and obesity. The higher prevalence of fast food consumption and sedentary activities among overweight and obese children, highlighted in this study, further confirms the need to promote health through education for healthy eating and lifestyle behavior.
Phytochemical composition, nutritional values, traditional uses of Tetrapleura tetraptera and Ricinodendron heudelotii and their pharmacological activities: an update review
Authors: PRINCIPAL Admin , DONGMO Olivette Laure Matafack , TADJOUA Herve Tchoumbou , TELEFO Phelix Bruno , POCOL Cristian Bianca , ANDREI Sanda 
Published: June 2022

The exploration of the use of natural herbals drug, especially plant parts, is a major area of focus. Medicinal plants are being increasingly used to manage a wide numerous ailment. Tetrapleura tetraptera and Ricinodendron heudelotii are known among medicinal plants having beneficial effects due to their several biological activities. The fruits and seeds of these plants are mostly used in many parts of Africa as spice for flavoring soup and making stews. This update review focused on the phytochemical characterization, traditional used, nutritional values and biological activities of these species. Both are known to possess macro-and micro-nutrients. They are rich in majority to the phytochemical’s compounds including polyphenols, flavonoids, tannins, reducing sugar, saponins and alkaloids etc. Their activities have been reported positive by several authors for both alcoholic and aqueous extractions. The plants exhibited appreciable antioxidant, anti-inflammatory and good antimicrobial activities against the test microorganisms justifying their broad-spectrum use. The hypolipidaemian, hypocholesterolaemian and hypoglycaemic properties have been proven to be efficacy especially for the plant Tetrapleura tetraptera and much practice remains to be done with Ricinodendron heudelotii. The confirmation of these biological activities is related to the high content of bioactive molecules conferring beneficial properties to plants.
Only ! know my gender: The individualist turn in gender theory and politics, and the right-wing opposition
Authors: Kováts Eszter 
Published: June 2022

The goal of this theoretical paper is to link right-wing anti-gender claims to real processes of the individualization of gender analysis in light of the critical literature on how neoliberal ideology has been affecting feminist politics and gender scholarship. While there has been reflexion about the co-optation of feminist vocabularies such as choice, liberation, and self-determination by neoliberal ideology for a long time, recent critiques add to this the individualist turn within gender theory, and feminist and LGBT activism too. I argue that uncovering these latter trends can contribute to a better understanding of the resonance of right-wing anti-gender messages among large segments of European electorates but also to (self-) critical discussion within gender theory and feminist and LGBT practice about the individualization of structural problems.
On (missing) critical distance and (involuntary) alliances: A warning about the reproduction of far-right ideologies in academic papers
Authors: Kocyba Piotr , Sommer Sebastian 
Published: June 2022

In recent years, far-right actors and movements have become a growing field of scientific research. The specific challenges of this political spectrum have led to a number of interdisciplinary debates on methodology and ethics. In this context, questions concerning a critical distance in research have played a crucial role since there is a constant risk of an involuntary reproduction and thus amplification of far-right ideology. The article ‘The transnationalization of ethno-nationalism: The case of the Identitarian Movement’ by Petra Mlejnková (published in Intersections) illustrates these pitfalls. It shows the consequences of a lack of reflexivity when approaching far-right activism. As a result, the author’s findings appear rather one-sided when contrasted with critical debates on far-right ideology and current methodological discussions. Moreover, the presentation of the results creates the impression of, at least implicit, empathy towards the ‘Identitarian Movement.’ This, in turn, shows the risk of scientific research turning unintentionally into a (discursive) ally of the far-right and promoting ideologies of inequality.
Adherence of patients with atrial fibrillation after acute coronary syndrome to antithrombotic therapy at stage III of cardiac rehabilitation: data from the local register of the Kirov region
Authors: Tarlovskaya E. I. , Dorofeeva J. A. 
Published: June 2022

Aim To evaluate the quality of antithrombotic therapy (ATT) in patients with atrial fibrillation (AF) after acute coronary syndrome (ACS) at stage 3 of rehabilitation.Material and methods The registry included 163 patients with AF (mean age, 65.0 [59.0; 72.0] years; 55.8 % men) undergoing rehabilitation after ACS (ACS <1 month ago) in the hospital of the Kirov State Medical University.Results Recommendations for 73.6 % of patients on ATT provided upon discharge from the hospital after stage 2 of rehabilitation were consistent with clinical guidelines (CG). During the entire stage 3, 25.8% of patients had acute cardiovascular complications (CVC) or urgent interventions (8.0% died). Furthermore, the ATT was actually consistent with CG only in 9.2 % of patients; in 21.5 %, errors in changing the ATT timing were detected; and in 84.1 %, various mistakes in the control of international normalized ratio were observed. On the whole, 3.6% of patients incorrectly adjusted their ATT independently, and for 15.3%, the attending physician made incorrect APT adjustments.Conclusion In AF patients after ACS who were undergoing stage 3 of rehabilitation, the quality of the ATT was low despite the recommendations at discharge from the hospital, which depended not only on the patient but also on the attending physician.
Integrating mobile technologies in a smart classroom to improve the quality of the educational process: Synergy of technological and pedagogical tools
Authors: Omirzak Islam , Alzhanov Aitugan , Kartashova Oxana , Ananishnev Vladimir 
Published: June 2022

The article describes the possibilities of mobile learning to implement the innovative educational concept of Smart Classroom. To increase the effectiveness of international partnerships and to develop opportunities for creating innovative projects in relevant socio-economic areas, an online forum "Engineering of educational courses in the medical and pharmaceutical industry" was held. Proficonf videoconferencing system made it possible to organize five online meetings on digital technologies in the training of modern pharmaceutical personnel within the concept of "Smart Classroom". The study results show that under digital transformation of the educational paradigm, it is advisable to consider a curriculum development strategy in the university ("Smart Campus"). Based on the study results, one can conclude that implementing the concept of "Smart Classroom" allows one to improve teaching methods and interaction between students at all stages of international educational relations.

Keywords: digital technology, mobile learning, Smart Classroom, Smart Environment, Smart Technology, student interaction.
Delegitimization of leadership in overcoming difficulties in online learning during the COVID-19 pandemic
Authors: Khairiah Khairiah , Mubaraq Zulfi , Asmendri Asmendri , Hendriani Suswati , Musa Dahniar Th. , Sihombing Adison Adrianus 
Published: June 2022

The general goal is not only to map the forms of difficulties in online learning, but also to analyze the reasons for the delegitimization of teacher. The specific purposes of this study are: (1) Delegitimization of teachers due to online learning, (2) The teacher's response to the pandemic condition, and (3) the implications of delegitimization on the teacher's life. This study used qualitative methods to explore primary and secondary data sources. The results of this study show (1) the occurrence of online learning difficulties as a form of delegitimization of teacher; (2) the occurrence of difficulties in establishing communication patterns, allocation of free time, innovation of activities that have a positive effect; and (3) there is a loss of identity, and teacher commitment in overcoming the difficulties of online learning. This paper concludes that there has been a delegitimization of teachers in online learning during the COVID-19 pandemic.

Keywords: Deligimation, Leadership, Difficulties, Online Learning, COVID-19 Pandemic