bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality-dependent Deep Learning for Safe Autonomous Guidewire Navigation
Authors: Ritter Jacqueline , Karstensen Lennart , Langejürgen Jens , Hatzl Johannes , Mathis-Ullrich Franziska , Uhl Christian 
Published: July 2022

Abstract
Cardiovascular diseases are the main cause of death worldwide. State-of-the-art treatment often includes the process of navigating endovascular instruments through the vasculature. Automation of the procedure receives much attention lately and may increase treatment quality and unburden clinicians. However, in order to ensure the patient’s safety the endovascular device needs to be steered carefully through the body. In this work, we present a collection of medical criteria that are considered by physicians during an intervention and that can be evaluated automatically enabling a highly objective assessment. Additionally, we trained an autonomous controller with deep reinforcement learning to gently navigate within a 2D simulation of an aortic arch. Among others, the controller reduced the maximum and mean contact force applied to the vessel walls by 43% and 29%, respectively.
Data-Efficient Vision Transformers for Multi-Label Disease Classification on Chest Radiographs
Authors: Behrendt Finn , Bhattacharya Debayan , Krüger Julia , Opfer Roland , Schlaefer Alexander 
Published: July 2022

Abstract
Radiographs are a versatile diagnostic tool for the detection and assessment of pathologies, for treatment planning or for navigation and localization purposes in clinical interventions. However, their interpretation and assessment by radiologists can be tedious and error-prone. Thus, a wide variety of deep learning methods have been proposed to support radiologists interpreting radiographs. Mostly, these approaches rely on convolutional neural networks (CNN) to extract features from images. Especially for the multi-label classification of pathologies on chest radiographs (Chest X-Rays, CXR), CNNs have proven to be well suited. On the Contrary, Vision Transformers (ViTs) have not been applied to this task despite their high classification performance on generic images and interpretable local saliency maps which could add value to clinical interventions. ViTs do not rely on convolutions but on patch-based self-attention and in contrast to CNNs, no prior knowledge of local connectivity is present. While this leads to increased capacity, ViTs typically require an excessive amount of training data which represents a hurdle in the medical domain as high costs are associated with collecting large medical data sets. In this work, we systematically compare the classification performance of ViTs and CNNs for different data set sizes and evaluate more data-efficient ViT variants (DeiT). Our results show that while the performance between ViTs and CNNs is on par with a small benefit for ViTs, DeiTs outperform the former if a reasonably large data set is available for training.
Is Eye-Tracking a Feasible Interaction Paradigm for Large Displays in the Sterile Field?
Authors: Ulas Behiye S. , Emirzeoglu Merve , Burgert Oliver 
Published: July 2022

Abstract
The paper describes how eye-tracking can be used to explore electronic patient records (EPR) in a sterile environment. As an information display, we used a system that we developed for the presentation of patient data and for supporting surgical hand disinfection. The eye-tracking was performed using the Tobii Eye Tracker 4C, and the connection between the eye-tracker and the HTML website was realized using the Tobii EyeX Chrome Extension. Interactions with the EPR are triggered by fixations of icons. The interaction was working as intended, but test persons reported a high mental load while using the system.
A ROS2-based Testbed Environment for Endovascular Robotic Systems
Authors: Eyberg Christoph , Karstensen Lennart , Pusch Tim , Horsch Johannes , Langejürgen Jens 
Published: July 2022

Abstract
Developing autonomous endovascular robotic systems requires physical testbeds to test control algorithms. Typically, such testbeds comprise of several hard- and software components along with a way of having these components communicate with each other. Building such a testbed is a multidisciplinary task which can be beyond the scope of expertise for research groups. The goal of this work is to facilitate setting up such testbeds in two ways: First, we propose a testbed architecture that allows to develop tracking, control and instrument manipulation systems separately by utilizing the ROS2 communication protocol. Secondly, we present a reliable yet straightforward to implement tracking algorithm for endovascular instruments that is built using only open-source software packages. The tracking algorithm is evaluated using both video camera and x-ray imaging and is found to meet the requirements for real time control algorithms. Furthermore, we show an example of the proposed modular testbed architecture as it is used in our lab. Both the modular testbed architecture and the open-source tracking algorithm may serve as helpful building blocks for other researchers in the field seeking to evaluate their control algorithms on physical testbeds.
Suitability Analysis of Industrial Drills for Minimally Invasive Skull Base Surgery
Authors: Knott Anna-Lena , Prinzen Tom , Klenzner Thomas , Schipper Jörg , Kristin Julia , Schmitt Robert H. 
Published: July 2022

Abstract
Medical drilling processes, especially in the area of the otobase, pose a high risk to the patient due to the heat generated and introduced into the tissue. Two measures of reducing the heat are the parameters of the drilling process and the optimisation of the drill geometry. A spiral drill and a singlelip drill are evaluated for their suitability as medical drills in skull base surgery with the objective of integrating a temperature sensor in the tip of the drill. The two drills were chosen because of their promising heat generation properties in pretesting. In this paper the chip formation behaviour and drilling channel quality are analysed. The single-lip drill shows lack in precision of the drilling channel and unsuitable bone chip transport, as material powder is left in the drilling channel. In contrast, the spiral drill shows a good transport of the chips and the drilling channel follows the planned path. As a result, the spiral drill is chosen for the further development of a drill with integrated temperature sensor for minimally invasive drilling.
Estimating Gripping Forces During Robot- Assisted Surgery Based on Motor Current
Authors: Schäfer Max B. , Meiringer Johannes G. , Nawratil Julia , Worbs Lukas , Giacoppo Giuliano A. , Pott Peter P. 
Published: July 2022

Abstract
Accurate measurement of interaction forces during robot-assisted surgery requires compact force sensing modalities in the surgical tools, thus might add considerable cost to the setup. Measuring the motor current to estimate gripping forces, is an advantageous approach since no expensive force sensor is needed. In this paper, a mechanical interface is presented, which allows actuating conventional articulated instruments for robot-assisted surgery. The interface features the estimation of static gripping forces at the instrument’s tip based on the motor current. The evaluation shows reproducible results, and the current-based approach seems to be a cost-efficient way to estimate gripping forces.
Panorama mapping of the colon – a phantom study with robotic endoscopy
Authors: Hackner Ralf , Eixelberger Thomas , Wittenberg Thomas 
Published: July 2022

Abstract
When documenting colonoscopic examinations, the challenge arises, that the exact location of the detected lesions (such as polyps) can usually only be determined with low precision. In order to improve the image-based documentation of such lesions with respect to their location and context, a system is currently investigated and developed, allowing the creation of a panoramic map of the interior of the colon’s lumen during an endoscopic examination. To evaluate the proposed algorithms, a 3D-printed colon phantom with known geometry has been developed. Furthermore, to obtain image sequences with precise and known motion during a simulated examination for test purposes, a robot was used to perform the insertion and withdrawal of the endoscope with constant speed and a steady viewing angle. The thus obtained image data is used to generate an ideal panoramic map using our the proposed stitching algorithm. Hence, it is possible to obtain reference maps of the phantom, which can be used to evaluate the quality of the algorithm.
Robotic assistant systems for surgical procedures of the anterior skull base
Authors: Schuler Patrick J. , Böhm Felix , Greve Jens , Scheithauer Marc , Hoffmann Thomas K. 
Published: July 2022

Abstract
Robot-assisted surgery (RAS) has been widely accepted in the clinical routine around the world with a focus on urology, gynecology and general surgery. Even transoral robotic surgery (TORS) is applied on a regular basis in some specialized medical centers. However, the anatomical constraints and the delicate procedures at the anterior skull base prevent the introduction of RAS until today. We have performed an extended literature research on robot-assisted skull base surgery and added our own pre-clinical experiences to the list of publications. The overview includes available systems, pre-clinical and clinical applications, specific limitations, remaining challenges and an outlook into future developments.
Shift dynamics of the groups of Fibonacci type
Authors: McDermott Kirk 
Published: July 2022

Abstract
We study the shift dynamics of the groups

G
=

G
n

⁢

(

x
0

⁢

x
m

⁢

x
k

-
1

)

G=G_{n}(x_{0}x_{m}x_{k}^{-1})

of Fibonacci type introduced by Johnson and Mawdesley.
The main result concerns the order of the shift automorphism of 𝐺 and determining whether it is an outer automorphism, and we find the latter occurs if and only if 𝐺 is not perfect.
A result of Bogley provides that the aspherical presentations determine groups admitting a free shift action by

Z
n

\mathbb{Z}_{n}

on the nonidentity elements of 𝐺, from which it follows that the shift is an outer automorphism of order 𝑛 when 𝐺 is nontrivial.
The focus of this paper is therefore on the non-aspherical cases, which include for example the Fibonacci and Sieradski groups.
With few exceptions, the fixed-point and freeness problems for the shift automorphism are solved, in some cases using computational and topological methods.
Ethics Political Communication Using Gayo Cultural System Approach (edet gayo)
Authors: Basri Hasan , Efendi Muhsin 
Published: July 2022

Ethics political communication used in the order in the government presented opinion or advice necessary keep a message manners according to customs culture gayo have separate ethics had meaning very important. Ethics political communication by the government to the society will affect any good; on the contrary, political communication also to the government will feed into aspects in improving the good order. Ethics political communication community groups as expressing an opinion society organizations politely and mannered use gayo culture and so is government response in accommodating the aspirations of the organizations. District of Aceh central gayo occupying an integral part of Indonesia. Those who have the character and values of the specific customs and culture of Indonesian society in general. The gayo customs and cultural values make the values of the Gayo customary philosophy in everyday life. The system of cultural values of the gayo community at events contains knowledge, beliefs, values, religion, norms, rules, and laws that become a reference for behavior in community life, the philosophical values of the gayo community, cannot be separated from the customs/culture of the gayo community as; Genap mupakat (democracy), amanat (integrity), tertip (orderly rules), alang tulung beret bantu (mutual help), gemasih (affection), setie (loyal), bersikekemelen (competing), dan mutentu (effective). Courteousness in conveying aspirations and opinions to the government and the government to the community must have politeness ethics in political communication to avoid inconsistencies and insecurity between the people and the government in Central Aceh
Single-cell transcriptomics of staged oocytes and somatic cells reveal novel regulators of follicle activation
Authors: Chen Yu-Ying , Russo Daniela D , Drake Riley S , Duncan Francesca E , Shalek Alex K , Goods Brittany A , Woodruff Teresa K 
Published: July 2022

In brief
Proper development of ovarian follicles, comprised of an oocyte and surrounding somatic cells, is essential to support female fertility and endocrine health. Here, we describe a method to isolate single oocytes and somatic cells from the earliest stage follicles, called primordial follicles, and we characterize signals that drive their activation.

Abstract
Primordial follicles are the first class of follicles formed in the mammalian ovary and are comprised of an oocyte surrounded by a layer of squamous pre-granulosa cells. This developmental class remains in a non-growing state until individual follicles activate to initiate folliculogenesis. What regulates the timing of follicle activation and the upstream signals that govern these processes are major unanswered questions in ovarian biology. This is partly due to the paucity of data on staged follicle cells since isolating and manipulating individual oocytes and somatic cells from early follicle stages are challenging. To date, most studies on isolated primordial follicles have been conducted on cells collected from animal-age- or oocyte size-specific samples, which encompass multiple follicular stages. Here, we report a method for collecting primordial follicles and their associated oocytes and somatic cells from neonatal murine ovaries using liberase, DNase I, and Accutase. This methodology allows for the identification and collection of follicles immediately post-activation enabling unprecedented interrogation of the primordial-to-primary follicle transition. Molecular profiling by single-cell RNA sequencing revealed that processes including organelle disassembly and cadherin binding were enriched in oocytes and somatic cells as they transitioned from primordial to the primary follicle stage. Furthermore, targets including WNT4, TGFB1, FOXO3, and a network of transcription factors were identified in the transitioning oocytes and somatic cells as potential upstream regulators that collectively may drive follicle activation. Taken together, we have developed a more precise characterization and selection method for studying staged-follicle cells, revealing several novel regulators of early folliculogenesis.
Coding for Initial and Subsequent Hospital Encounters
Authors:   American Academy of Pediatrics
Published: July 2022

This article reviews the Current Procedural Terminology (CPT®) codes and guidelines for selecting appropriate codes for evaluation and management (E/M) services provided to hospital patients in inpatient or observation stays. The following topics are reviewed:
Services that are designated as initial or subsequent encounters General differences in requirements of initial and subsequent encounter codes Guidelines for code selection by the admitting or attending physician Guidelines for code selection by physicians other than the admitting or attending physician
IDEOLOGI BENCANA DALAM PERSPEKTIF AL-QUR’AN: ANALISIS KATA FITNAH PADA SURAH AL-ANBIYA[21]:35 DENGAN TEORI MA’NA-CUM-MAGHZA)
Authors: Firdausiyah Umi Wasilatul , Hardivizon Hardivizon 
Published: July 2022

Diskursus dalam penelitian ini berupa ideologi bencana dalam perspektif Al-Qur’an, yang terfokus pada pembahasan kata fitnah dalam QS. Al-Anbiya [21]:35. Tujuan dari penelitian ini berupa upaya untuk menemukan kredibilitas makna dan eksistensi kata fitnah dalam al-Qur'an dengan bingkai teologi bencana. Metode penelitian yang digunakan penulis menggunakan jenis penelitian Library Research, dengan pengumpulan data berupa dokumentasi dan analisis data berupa metode tematik karena tidak semua ayat yang digunakan oleh penulis. Ditambah dengan teori hermeneutika ma’na-cum-maghza, yang dilengkapi dengan triangulasi sumber sebagai keabsahan datanya. Hasil penelitian ini yang terbingkai dalam teologi bencana terhadap kata fitnah pada QS. Al-Anbiya [21]:35 memiliki artian sebagai suatu bencana bagi setiap individu maupun kelompok dan eksistensi kata fitnah memiliki dua pembagian yakni keburukan dan kebaikan, serta suatu kematian dan ujian kehidupan merupakan keniscayaan yang pasti akan terjadi, hal tersebut juga sebagai cobaan dari ujian iman. Penafsiran QS. Al-Anbiya [21]:35 dengan ma’na-cum-maghza, juga beimplikasi pada kajian tafsir kontemporer dan dapat mempengarui mindset masyarakat terhadap pemaknaan maupun pengucapan kata fitnah.
PENGENALAN BUDAYA SUNDA PADA ANAK USIA DINI: SEBUAH NARRATIVE REVIEW
Authors: Rizkiyani Fanny , Sari Dianti Yunia 
Published: July 2022

Penelitian ini menelaah penelitian-penelitian sebelumnya mengenai integrasi pengenalan budaya Sunda dalam pembelajaran di tingkat anak usia dini. Adapun literatur-literatur yang dimasukkan dalam penelitian ini adalah literatur berbentuk artikel yang dipublikasikan antara rentang waktu 2019-2022. Pencarian dalam database Google Scholar memunculkan sejumlah 787 literatur, dan hanya 9 artikel jurnal yang dipilih untuk dimasukkan dalam penelitian ini. Berdasarkan hasil penelitian ini, elemen-elemen dari budaya Sunda yang sudah dikenalkan dalam pembelajaran di kalangan anak usia dini, di antaranya, adalah bahasa Sunda, alat transportasi tradisional, alat bertani tradisional, tarian dan permainan tradisional, serta seni tradisional. Pengenalan budaya Sunda tersebut diintegrasikan dalam pembelajaran yang bertujuan meningkatkan keterampilan anak dalam aspek-aspek perkembangan tertentu, yaitu bahasa, fisik motorik, kognitif, dan sosial emosional. Mempertimbangkan karakter pendidikan anak usia dini yang holistik integratif, pengenalan budaya Sunda memiliki potensi untuk diintegrasikan dalam pembelajaran yang menargetkan peningkatkan beberapa aspek perkembangan anak secara simultan.
Comprehensive assessment of coastal tourism potential in Vietnam
Authors: Hoang Thi Thu Huong , Kinh Dang Bac , Van Rompaey Anton 
Published: July 2022

Coastal tourism includes diverse resources and activities, so a comprehensive assessment is required to implement the sensible use of tourism potential. This paper deals with a comprehensive assessment of tourism potential in the coastal region of Vietnam based on 4 dimensions: attractiveness, accessibility, tourism service quality, and environmental quality & safety, covering 23 criteria. Analysis Hierarchy Process (AHP), Principal Component Analysis (PCA), Correlation analysis, and a Geographic Information System (GIS) were used in this study. AHP was applied to determine a weighting coefficient for each criterion. PCA was processed next to AHP, allowing a combination of the considered sites' internal and external tourism potentials. Then the relationship between tourism potential and revenue is tested based on correlation analysis. The results show that the provinces in the South-Central region have the highest potential for coastal tourism development, followed by the North Central region. The Northern and Southeast region provinces and Mekong River Delta have low potential. However, there are still some bright spots for coastal tourism development in these regions, such as Quang Ninh, Ho Chi Minh City, Ba Ria-Vung Tau, and Kien Giang. This research also shows that tourism revenue depends more on external factors (supporting factors) than internal factors (tourism resources). Finally, the study proposed development plans for each group of coastal provinces based on their strengths and weaknesses, as well as suggested solutions to overcome the limitations of seasonality and the impact of climate change on Vietnam's coastal tourism.
ON SOLVING AN ENHANCED EVASION PROBLEM FOR LINEAR DISCRETE–TIME SYSTEMS
Authors: Kostousova Elena K. 
Published: July 2022

We consider the problem of an enhanced evasion for linear discrete-time systems, where there are two conflicting bounded controls and the aim of one of them is to be guaranteed to avoid the trajectory hitting a given target set at a given final time and also at intermediate instants. First we outline a common solution scheme based on the construction of so called solvability tubes or repulsive tubes. Then a much more quick and simple for realization method based on the construction of the tubes with parallelepiped-valued cross-sections is presented under assumptions that the target set is a parallelepiped and parallelotope-valued constraints on controls are imposed. An example illustrating this method is considered.
MONOPOLISTIC COMPETITION MODEL WITH ENTRANCE FEE
Authors: Tilzo Olga A. 
Published: July 2022

We study the monopolistic competition model with producer-retailer-consumers two-level interaction. The industry is organized according to the Dixit–Stiglitz model. The retailer is the only monopolist. A quadratic utility function represents consumer preferences. We consider the case of the retailer's leadership; namely, we study two types of behavior: with and without the free entry condition. Earlier, we obtained the result: to increase social welfare and/or consumer surplus, the government needs to subsidize (not tax!) retailers. In the presented paper, we develop these results for the situation when the producer imposes an entrance fee for retailers.
The Moro reflex: insights into the pathophysiology of generalized tonic‐clonic seizures and infantile spasms
Authors: Brigo Francesco , Porro Alessandro , Trinka Eugen 
Published: July 2022

AbstractThe Moro reflex (MR) is a primitive reflex that disappears after the first three months of life. It was described by the Austrian paediatrician Ernst Moro (1874–1951) in 1918, although the earliest visual representation of the MR dates back to the first half of the 14th Century, in a fresco by Ambrogio Lorenzetti (1290‐1348). The neural centre underlying the MR is located in the lower part of the brainstem since it can be elicited also in anencephalic infants, as shown by the Austrian neurologist Eduard Gamper (1887‐1938) in the first medical description of anencephaly (1926). The MR is due to the activation of an archaic neural circuit present in the newborn, the activity of which is later inhibited by the upper brain structures. Given their semiological resemblance, epileptic spasms and generalized tonic‐clonic seizures might be due (at least partly) to the pathological activation of the same neural archaic circuit involved in the genesis of the MR. The neuronal network underlying these different phenomena might be located in the pons. In these seizure types, the activation of the same neural circuitry involved in the MR could occur through either direct excitation or through an indirect “liberating” mechanism, secondary to epileptic disruption of cortical inhibitory control on subcortical structures. The movements of the upper extremities in epileptic spasms, in the initial phase of generalized tonic‐clonic seizures, and the MR might involve a distinct neural circuitry, which is (or becomes) hyperexcitable as a consequence of a pathological condition (epilepsy) or physiological brain immaturity (the MR).