bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parents’ experience in the Ronald McDonald Houses
Authors: Cosquer M. , Jousselme C. 
Published: September 2022

IntroductionChild hospitalization is a difficult event in the life for the whole family, probably worst for families coming from far away, specially for accommodation. Ronald McDonald Houses (RMH) created in the immediate proximity of pediatric departments of hospitals, allows hospitalized children to benefit from the presence of his family nearby. The hypothesis that the family is stronger when it is grouped together (the “family-centered-care” concept) remains difficult to demonstrate (Cochrane, 2012). In France, there is no study describing the interest of such places, and families experiences.ObjectivesOur objectives are to describe the experience of parents in French RMH.MethodsA cross-sectional study conducted between February and April 2016, invited 50 families to participate in the 9 French RMH, by feeling an anonymous questionnaire (socio-demographic characteristics, items related to hospitalization, anxiety and depression scale -HADS, conditions of stay at the house). Descriptive statistics presented mothers and fathers experience.Results
Parents of 333 hospitalized child participated : 320 mothers, 246 fathers. 44.1% of child were aged less than one year. Services more represented were : intensive care unit, oncology and neonatal. Parents were socially rather disadvantaged, living mainly in couples, with an estimated mean home-hospital time of 2 hours. They reported financial problems (>40%), sleep deprivation (>1.5 hours), and anxiety-depressive disorders: anxiety (>50%) and depression (>20%). Satisfaction staying in the house was extremely high (>95%).Conclusions
We observe an undeniable added value of the RMH in the care. Nevertheless, the high level of psychological suffering shows the importance of offering help at the psycho-social level.DisclosureNo significant relationships.
Motor learning principles in the service of speech disorders
Authors: Vashdi E. 
Published: September 2022

IntroductionChildhood Apraxia of Speech (CAS) was declared as a motor speech disorder by ASHA (2007). Yet, until then it was mainly addressed as a phonological disorder and until these days, 14 years later, the treatment of CAS is yet to be motor based worldwide. Professionals finds it hard to diagnose it clearly due to comorbidity with communication and language disorders.ObjectivesThis non clarity might lead to non-accurate treatment since the essence of the syndrome is not addressed. An accurate treatment will integrate knowledge from several domains: communication, Language, Sensory, behavioural, emotional, cognitive and, the most important one for CAS, motor learning.MethodsMotor learning is an area of knowledge which is learnt usually in sport academy, while Its main practical purpose is to improve training methods in sport. The use of motor learning knowledge doesn’t belong to the world of sport primarily but rather to the world of movement wherever it exists. One of the fascinating areas of movement is speech.Results

Speech in its basic form is motor based, before it being used as a motor tool for language and communication. It is the most complicated motor task in the human body since for every syllable we activate directly and indirectly over 100 muscles. The children who can’t acquire speech spontaneously due to severe deficit in motor planning, need to practice motor speech tasks repeatedly and accurately.ConclusionsThis lecture will present the use of 20 motor learning principles in the speech treatment via the VML methodDisclosureI am the founder of the VML method while teaching it in various countries
Prevalence of cognitive impairment and its association with clinical variables among Patients with Mood Disorders
Authors: Nahar S. , Khan M. 
Published: September 2022

IntroductionMood disorders are common psychiatric illnesses with major disability and mortality and it is estimated that 8% to 20% of the population experience a depressive episode at some point in their lives.ObjectivesTo find out the prevalence of cognitive impairment among patients with Mood Disorders i.e, Major Depressive Disorder
(MDD) and Bipolar Mood Disorder (BMD), etc. and to find out the status of cognitive impairment with clinical variables of Mood Disorders.MethodsThis was a descriptive cross-sectional study conducted among the patients attending both the inpatient and outpatient departments of the National Institute of Mental Health, Dhaka. The duration of the study was fourteen months starting from July 2011 to September 2012. A total of one hundred and thirty-three (n=133) patients who fulfilled the inclusion-exclusion criteria were selected.ResultsThe mean age of onset of mood disorder was 30.1± 10.7years.60.2% were male and 39.8% were female respondents. Cognitive impairment was found among 43.6% of the respondents. A substantial proportion of the study population was found to have cognitive impairment. In this study, the cognitive status of the respondents was not associated with the duration of illness (p>0.5).ConclusionsSo assessment of cognitive status should be an essential part of the management of this group of people.DisclosureNo significant relationships.
Mental health treatments in an Italian prison: the Parma integrated approach
Authors: Pelizza L. , Maestri D. , Paulillo G. , Pellegrini P. 
Published: September 2022

IntroductionMental health interventions for Italian (and European) prisoners with mental disorders remain a problematic issue, despite radical changes in general psychiatric care and a 2008 major government reform transferring mental health care in prison to the National Health Service. Indeed, according to the American Psychological Association, 64% of incarcerated individuals report mental health concerns.Objectives
The aim of this study is to describe the mental health intervention model implemented since January 2020 for prisoners allocated in the Parma Penitentiary Institutes (PPI). This approach is specifically based on specialized, “person-centered” and “person-tailored” therapeutic-rehabilitation plans in line with psychiatric treatments usually provided in community mental health-care centers of the Parma Department of Mental Health.MethodsAll the processes and procedures included in the PPI intervention model were first carefully described, paying special attention to the service for newly admitted prisoners and each typology of specialized therapeutic-rehabilitation treatment potentially provided. Additionally, a preliminary descriptive process analysis of the first six months of clinical activity was also performed.Results
Since January 2020, 178 individuals entered the PPI service for newly admitted prisoners. In total, 83 (46.7%) of them were engaged in the services of the PPI mental health-care team (35 with pathological addiction and 48 with mental disorders): 56 prisoners were offered an integrated mental health intervention and 27 exclusively an individual psychological or psychiatric treatment.ConclusionsThe results support the potential applicability of an integrated mental health intervention in prison, planning a person-tailored rehabilitation in close collaboration with the prisoners, their families and the local mental health/social services.DisclosureNo significant relationships.
Two of us live in this body
Authors: Palomo Monge M. , Pérez Fominaya M. , López Rodrigo M.V. , Osca Oliver A. , Tascón Guerra M.F. , García Montero C. , Ros Font V. 
Published: September 2022

IntroductionThe dissociative disorders are characterized by a disruption of and/or discontinuity in the normal integration of consciousness, memory, identity, emotion, perception, body representation, motor control, and behavior.ObjectivesWe present the case of a 22-year-old patient, who has been following up for just over a year. The patient refers that two people inhabit her body, talk to each other, exchange opinions and both have control over the body, one giving the turn to the other depending on the circumstances. To this is added delusional symptoms of grandeur and sensorial-perceptual symptoms. In turn, depressive symptoms have appeared that have led the patient to have several suicide attempts throughout the follow-up
time.MethodsDuring this time, the patient has required hospital admission on two occasions due to the autolytic ideation. Treatment with neuroleptics and antidepressants has been established that have helped control delusions and thoughts of death, but not the dissociative clinic.ResultsDissociative Identity disorder 300.14 (F44.81)ConclusionsThe different symptoms presented by the patient, as well as the social and occupational deterioration that he presents, make this an extremely complicated case, both in diagnosis and in treatment. Dissociative identity disorder has been very controversial, changing its diagnostic criteria over time. More studies are needed and perhaps future research can give us more clues about this disorder.DisclosureNo significant relationships.
The effect of childhood trauma and trauma-focused psychotherapy on blood expression of MED22 in patients with major depressive disorder
Authors: Minelli A. , Maffioletti E. , Carvalho Silva R. , Cattaneo A. , Perusi G. , Bortolomasi M. , Gennarelli M. 
Published: September 2022

IntroductionThe only available genome-wide study (Minelli et al., 2018) indicated an association between the neglect CT and MED22, a transcriptional factor gene.ObjectivesTo verify how the dysregulation of MED22 could be affected by environmental and genetic factors, we carried out an analysis on these components and a longitudinal study concerning the effect of trauma-focused psychotherapy in MDD patients that experienced CT.Methods
On a large mRNA sequencing dataset including 368 MDD patients we computed the genetic (GReX) and the environmental (EReX) components affecting gene expression in relation to CT. Furthermore, we measured the expression of MED22 in 22 MDD patients treated with trauma-focused psychotherapy.Results
The dissection of MED22 expression profiles revealed an association of neglect with environmental and genetic components (p=6x10-3 p=2.6x10-4). Furthermore, in an independent cohort of 177 controls, we also observed a significant association between cis-eSNPs of MED22 and higher neuroticism scores (best p-value: 0.00848) that are usually associated with a decreased amount of resilience to stress events. Finally, the results of psychotherapy revealed a reduction of depressive symptomatology (p<0.001) and 73% of patients resulted responders at the follow-up visit. MED22 expression during psychotherapy showed a change trend (p=0.057) with an interaction effect with response (p=0.035). Responder and non-responder patients showed MED22 expression differences at different trauma-focused psychotherapy timepoints (p=0.15; p=0.012) and at the follow-up (p=0.021).ConclusionsOur results provide insights suggesting that some biological and clinical consequences of CT depend on genetic background and environmental factors that could induce vulnerability or resilience to stressful life events.DisclosureNo significant relationships.
Possible Therapeutics Effects of Ayahuasca, a Psychedelic Compound
Authors: Silva L. , Bravo L. 
Published: September 2022

IntroductionAyahuasca is an hallucinogenic tea prepared from the Amazonian vine Banisteriopsis caapi and the leaves of the plant Psychotria Viridis. Banisteriopsis caapi contains monoamine oxidase inhibitors (MAO) that render the N, N-dimethyltryptamine (DMT) of Psychotria Viridis active. This brew is being used as a sacrament in syncretic religions in urban areas of Brazil and worldwide with the purpose of enabling a spiritual experience as well as healing for a variety of conditions such as drug addiction, depression and anxiety disorders.ObjectivesThis work aims to provide an understanding on the potential benefits of ayahuasca in psychiatric symptoms, as well as its neuropsychological functioning, neuroimaging and adverse events.MethodsA non-systematic review was performed on PubMed database and Google Scholar, using the key words “Ayahuasca, Drug Addiction, Psychedelics, DMT, Neuroplasticity”. The review included experimental studies in humans, observational studies, systemic review articles and clinical trials.ResultsIn a randomized placebo-controlled trial, ayahuasca had a significant antidepressant effect when compared to the placebo group. Long term ayahuasca usage was associated with structural alterations in the medial parts of the brain with no evidence of increased psychopathology or worse neuropsychological functioning. According to reviewed studies the incident of prolonged psychotic reaction among ayahuasca users is rare and the causal relation with ayahuasca is sometimes difficult to establish.Conclusions
Despite the promising results, more controlled double-blinded studies with larger populations are necessary to better understand the therapeutic potentials and side effects of ayahuasca.DisclosureNo significant relationships.
Body Self-Perception and Sense of Agency: a systematic review of literature
Authors: Danilo S. , Virdia L. , Rogier G. , Beomonte Zobel S. , Cavalli R. , Civilla C. , Velotti P. 
Published: September 2022

IntroductionThe sense of agency concerns the experience of controlling our actions, referring both to superior and lower levels of psychological functioning that are also related to the physical dimension of agency. Diverse clinical conditions affect the awareness of being a bodily and agentive self.ObjectivesThe aim of this systematic review was to provide a comprehensive evaluation of the relationship between individual sense of agency and body perception.MethodsPsycINFO, Psycharticle, Medline, Web of Science and Scopus were systematically searched for articles published until 19/10/2020.ResultsAfter removing duplicates, a total of 2.556 records was screened. Fifteen articles were selected based on the inclusion criteria fixed for the systematic review.ConclusionsIn the last decades, this line of research seems to attract a growing number of studies.However, these studies are affected by a great heterogeneity in the investigation of both constructs.Body perception and sense agency were operationalized across research in diverse ways, making the evaluation of the relationship between them very difficult. In addition, there is a paucity of studies investigating the relationship between body perception and agency among individuals suffering from specific psychopathology or physical diseases. According to literature review, the main objective for future research is to develop more robust approaches to estimate the variability of these constructs such as their relationship.DisclosureNo significant relationships.
Paroxetine-induced galactorrhea
Authors: Petrykiv S. , Arts M. , De Jonge L. 
Published: September 2022

IntroductionAntidepressant-induced galactorrhea and increases in prolactin levels have been sporadically reported among SSRI-related side effects.ObjectivesCurrent rapport presents a case of 39 y.o. female who developed several adverse effects on paroxetine - including galactorrhoea - which improved on discontinuation of the drug.MethodsCase discussion of 39-year old woman who was treated with paroxetine for her panic disorder and developed galactorrhoea with hyperprolactinemia that resolved upon discontinuation of the drug. Additionally, authors performed the literature search using PubMed and Embase to review the similar cases and used PDSP Database to assess the latest pharmacodynamic (PD) properties of paroxetine and other SSRI’s.ResultsLiterature review (1966–2020) revealed 24 prior published case reports of SSRI-induced galactorrhea in users of paroxetine (n=4), escitalopram (n=4), sertraline (n=2), citalopram (n=2), fluoxetine (n=3), fluvoxamine (n=2) and other non-assessable reports (n=7). Elevated prolactin levels were mostly observed with paroxetine and escitalopram and rarely with fluoxetine, fluvoxamine and sertraline. PD-assessment showed the highest binding affinity of paroxetine and escitalopram to SERT (kPi = 0.07-0.2 and 0.8-1.1 nmol/L respectively) compared to other SSRI’s, in absence of other relevant PD-propertiesConclusionsIncreasing body of evidence shows that galactorrhea does occur among paroxetine female users. Pharmacodynamic mechanism of action is poorly understood but given the modern insights in relationship in serotonin and dopamine circuits, we suggest that strong SERT inhibitory properties of paroxetine might lead to a tonic suppressive influence on dopamine neurotransmission. This physiological link may explain an increase in prolactin levels through dopamine depletion in the tuberoinfundibular pathway.DisclosureNo significant relationships.
Role of nurses and the nursing assistants in the implementation and monitoring of physical restraint in psychiatry
Authors: Maatouk O. , Larnaout A. , Abassi B. , Lansari R. , Staali N. , Melki W. 
Published: September 2022

IntroductionPhysical restraint is a therapeutic procedure allowing to immobilize an agitated patient.Although it is an effective method especially in the states of psychomotor instability, its practice is not devoid of risks which imposes a codified technique with particular monitoring.ObjectivesThe aim of this work was to evaluate the knowledge of nurses and nursing assistants in the practice and monitoring of physical restraint and to establish a suitble protocol codifing it.MethodsOur study was a descriptive cross-sectional study based on a questionnaire grouping together a set of questions on general and professional characteristics, the decision of physical restraint, its prescription, its means, its monitoring, informing the patient and his relatives, physical restraint’s risks, the patient’s experience, the caregiver’s experience as well as the relationship between caregiver and patient. Our target population was composed of nurses and orderlies of the psychiatry department <<D>> of the Razi hospital in Manouba.ResultsWe collected 30 professinals.90% of them were women. 30% of our sample had less than five years of experience. Only 23.30% of caregivers had mental health training at the beginning of their professional career. 50% of them received training focused on physical restraint.83.30% reported using physical restraint for psychomotor agitation.56.6% ignored the psychological effects of the physical straint on patients. 73.3% of caregivers informed patients before straint.ConclusionsA physical restraint protocol, codifying the technique of implementation and monitoring parameters is needed in order to improve the relation patient-cargiver and ensure an optimal care .DisclosureNo significant relationships.
Use of mindfulness-based interventions for parental stress in relation with ASD: A review
Authors: Yesilkaya M. , Mijail Magallon Neri E. 
Published: September 2022

IntroductionChildren with ASD may present their parents with several challenges, most notably aggressive and destructive behaviors. Parents of children with ASD typically experience more stress, depressive and anxiety symptoms than other parents. Mindfulness-based interventions are reported to be effective in reducing parental stress along with improving the challenging behaviors of their childrenObjectivesThe current review aimed to investigate if the use of mindfulness-based interventions is beneficial to reduce parental stress when caring for children with ASD.MethodsThe databases of PsycINFO and PubMED were used. The variables studied in this systematic review were Autism, Parental stress, and Mindfulness. Inclusion criteria were that all articles should be academic journals, and with a full text available in English during the last 20 years.ResultsCompared to other behavioral approaches, mindfulness-based interventions showed statistically significant results in reducing the stress levels of parents as well as improving their children’s challenging behaviors.ConclusionsMost of the studies in the current review indicated that mindfulness-based interventions are beneficial in improving the stress level of parents.DisclosureNo significant relationships.
Psychiatric manifestations of measles encephalitis: About a case report
Authors: Bouhamed M. , Feki I. , Guermazi A. , Guermazi F. , Sallemi R. , Masmoudi J. 
Published: September 2022

IntroductionAcute measles encephalitis is a pathology of the central nervous system. It is most frequent in children but can also be described in adults. Given the rarity of this pathology, we present the case of this patient.Objectives
present a rare neuropsychiatric complication of measlesMethodsPrésentation d’un cas clinique d’encéphalite rougeoleuse et revue de la littératureResultsMrs. HJ, 45 years old, without any somatic history, was followed for an antisocial personality with a substance use disorder. She consulted the emergency for psychomotor agitation, a fever of 39, and a rash on the face, thorax, and limbs. At the psychiatric interview, she was disoriented and very unstable. She seemed to be hallucinating.The brain imaging and the lumbar puncture (CT scan and brain MRI) were without abnormality. The rapid test (HIV) was negative and the biological check-up showed a hyperleukocytosis at 12660 and a crp at 138. The patient was put on double antibiotic therapy.
The evolution was marked by the non-improvement of the symptomatology with the persistence of agitation. Her speech was almost absent with a refusal to answer and to execute orders. She maintained certain postures. The patient was put on 400 mg of amisulpride.After recovery of the viral serology, the diagnosis of a measles encephalopathy was confirmed (IgM positive) and the patient improved after a few days of hospitalization and was addressed to the psychiatric outpatient clinic.ConclusionsMeasles encephalitis is a rare but serious complication that requires multidisciplinary managementDisclosureNo significant relationships.
Mental disorders among sexual and gender minorities
Authors: Khouadja S. , Zaouali F. , El Echi M. , Najjar C. , Zarrouk L. 
Published: September 2022

IntroductionThe term “Sexual and Gender Minorities” includes lesbian, gay, bisexual, transgender, queer, intersex and/or asexual populations. It was introduced in the MeSH Database in 2018. Mental health research on sexual and gender minority populations is gaining momentum.ObjectivesTo describe mental disorders among sexual and gender minorities.MethodsThis is a review of the literature via Medline. The database was searched using the keyword combination “sexual gender minorities” OR “homosexuality” OR “bisexuality” OR “transgender persons” OR “intersex persons” AND “mental disorders”. The filters applied were Full text, Meta-Analysis, Systematic Review and in the last 5 years.ResultsA total of 59 articles were included. The lowest rates of depression and anxiety were reported among heterosexual people. Depressive symptoms, suicidality, interpersonal trauma exposure, substance use disorders, anxiety, and general distress have been consistently elevated among transgender and gender non-conforming people. Among transgender people, the prevalence of binge drinking ranged from 7%-61%. Depression was the most frequent mental disorder among sexual minority men (43.2%) followed by anxiety (32.2%), suicidal ideation (21.2%), suicide plans (6.2%) and suicide attempts (7.3%). Eating disorders were more frequent among sexual minority women compared with heterosexual peers. Compared with heterosexual youth, sexual minority youth had 123% to 623% higher odds of lifetime substance use, 82% to 317% higher odds of depressive symptoms and suicidality and 20% to 280% higher odds of violence victimization.ConclusionsThe prevalence of mental disorders is high among sexual and gender minorities for whom mental health prevention and treatment programs are needed.DisclosureNo significant relationships.