bluuebunny/crossref_metadata_2025_split huggingface dataset:
Covid-19 Pandemi Sürecinin Akademisyenlere Getirdiği Avantajlar ve Dezavantajlar: Kahramanmaraş Sütçü İmam Üniversitesi Örneği
Authors: CAN Niyazi , HATUNOĞLU Mihriban 
Published: May 2022

Since the beginning of 2020, the coronavirus (Covid-19) pandemic has affected the world in many areas. It appears in education within these areas. Due to the pandemic education to many countries, including Turkey remotely (online) is continuing its training platform. Including in higher education in Turkey the rapid transition to distance education at all education levels required sudden infrastructure improvement and rapid adaptation to this process. The opinions of the academicians about the online courses made as a result of the measures taken in this process are important in terms of determining the limitations, quality, advantages and disadvantages of distance education. Thanks to the answers received from the academicians, it is aimed to determine the negative situations encountered in this process and to pave the way for a better education system.
This study aims to understand the advantages and disadvantages of distance education for academicians, who are important stakeholders of distance education during the Covid-19 pandemic process. Therefore, the study was designed with phenomenology, one of the qualitative research methods. 14 academicians from Kahramanmaraş Sütçü İmam University (KSÜ) participated in the study. Research participants were selected using the typical case method. In order to obtain research data, the approval of the Ethics Committee of KSU was first obtained. Questions were directed to academicians with a semi-structured interview form developed in line with expert opinions. Open-ended form and semi-structured interview forms were used as data collection tools. Content analysis method was used in the analysis of the data, interpretations were made by making direct quotes from intermediate opinions, and the findings were compared with the quotations, and the results and suggestions were developed.
Authors: Haryuni Sri , Perdana Idola , Yunalia Endang Mei , Handayani Wiwik 
Published: May 2022

ABSTRACT
Diarrhea is a condition in which the frequency of bowel movements is more than 4 times in infants and more than 3 times in children, characterized by the consistency of liquid stools, green in color and sometimes mixed with mucus, blood or mucus. Complications that occur due to diarrhea are dehydration, hypovolemic shock, hypokalemia, hypoglycemia, intolerance secondary to intestinal mucosal villi damage and lactase enzyme deficiency, seizures, hypertonic dehydration, protein energy malnutrition (due to vomiting and diarrhea, if prolonged or chronic). Dehydration is usually characterized by changes in vital signs, such as body temperature, pulse rate, respiratory rate, and blood pressure. This study aims to determine the relationship between pulse frequency with the degree of dehydration in children with diarrhea in the ER Wamena Hospital. This research is a quantitative research with correlation analytic method through cross sectional approach. Secondary data collection using a data collection sheet with a sample of 380 people. The independent variables are body temperature and pulse rate, while the dependent variable is the degree of dehydration. Based on the results of the Spearman rank test, it was found that there was a relationship between pulse frequency and the degree of dehydration with p value = 0.013 and the strength of the relationship was very weak. It is recommended for further researchers to conduct further research on other factors related to diarrhea
Keywords: degree of dehydration, diarrhea, heart rate
Reka Bentuk Pembangunan Model Pedagogi Terbeza Berasaskan Elemen Kandungan Pelajaran Tilawah Al-Quran Sekolah Rendah di Malaysia: Pendekatan Fuzzy Delphi
Authors: Mustaffa Zurina , Hussin Zaharah 
Published: May 2022

Kajian ini bertujuan untuk mendapatkan konsensus pakar terhadap keperluan elemen utama dan kedudukan (ranking) mengikut keutamaan bagi setiap item dalam reka bentuk pembangunan Model Pedagogi Terbeza berasaskan elemen kandungan pelajaran tilawah al-Quran di sekolah rendah. Di dalam kajian ini, pengkaji menggunakan kaedah kajian kuantitatif dengan menggunakan pendekatan Fuzzy Delphi Method. Pengkaji juga menggunakan khidmat 16 orang pakar dari pelbagai bidang iaitu bidang pedagogi dan pendidikan al-Quran. Borang soal selidik mengandungi 16 item yang melibatkan tiga konstruk utama iaitu (i) perancangan pengajaran, (ii) pengetahuan isi kandungan pelajaran dan (iii) amalan guru dalam mengubah suai kandungan pelajaran. Data dianalisis dengan menggunakan software Fudelo. Dapatan kajian menunjukkan kesemua item yang dicadangkan oleh pengkaji melepasi ketiga-tiga syarat Fuzzy Delphi Method (FDM) iaitu nilai threshold (d) kurang atau sama daripada 0.2, jumlah kesepakatan pakar melebihi atau sama dengan 75% dan nilai alpha cut iaitu nilai defuzzification melebihi atau sama dengan 0.5. Dapatan keseluruhan menunjukkan terdapat konsensus pakar bagi item-item yang dicadangkan dalam reka bentuk Model Pedagogi Terbeza berasaskan elemen kandungan pelajaran tilawah al-Quran sekolah rendah. Reka bentuk model ini diharap dapat membantu guru Pendidikan Islam dalam menguasai kandungan pelajaran tilawah al-Quran dengan lebih baik dan kompeten.

This study aims to obtain expert consensus on the need for key elements and rank each item in order of priority in the development of different pedagogical models based on the content elements of Quran recitation lessons in primary schools. In this study, the researcher used a quantitative research method by using the Fuzzy Delphi Method approach. The researcher also used the services of 16 experts from various fields, namely the field of pedagogy and Quranic education. The questionnaire contains 16 items involving three main constructs, namely (i) lesson planning, (ii) knowledge of lesson content, and (iii) teacher practise in modifying lesson content. The data was analysed using Fudelo software. The findings showed that all items proposed by the researcher passed the three conditions of the Fuzzy Delphi Method (FDM): the threshold value (d) is less than or equal to 0.2, the total expert agreement exceeds or equals 75%, and the alpha cut value, which is the defuzzification value, exceeds or equals 0.5. The overall findings indicate that there is expert consensus for the items proposed in the design of the differentiated pedagogy model based on the content elements of primary school Quran recitation lessons. The design of this model is expected to help Islamic Education teachers master the content of Quran recitation lessons better and more competently.
Transcutaneous Electrical Nerve Stimulation and Dynamic Neuromuscular Stabilization are Equally Effective in Patients of Different Ages with Spinal Degeneration
Authors: Danytė Skirmantė , Dudonienė Vilma 
Published: May 2022

Background. Back pain is the most common symptom caused by intervertebral disc degeneration, thus various interventions are used to relieve it, including transcutaneous electrical nerve stimulation and dynamic neuromuscular stabilization.
The aim. To determine the effect of transcutaneous electrical nerve stimulation and dynamic neuromuscular stabilization on the static endurance of trunk muscles, back pain and functional disability in individuals of different ages with intervertebral disc degeneration.
Methods. The study included 40 individuals diagnosed with lumbar disc degeneration. According to age, the subjects were divided into two groups: the first (n = 22), with a mean age of 34.27 ± 7.81 yrs. and the second (n = 18) with a mean age of 55.28 ± 5.86 yrs. Both groups underwent transcutaneous electrical nerve stimulation and dynamic neuromuscular stabilization to relieve back pain. The duration of the study was 8 weeks. Before the intervention, after 4 weeks and after 8 weeks of the intervention, the static endurance of the trunk muscles and the pain intensity were assessed according to the numerical analog pain scale and the functional disability according to the Roland-Morris questionnaire.
Results. Transcutaneous electrical nerve stimulation and dynamic neuromuscular stabilization of eight-week duration significantly increased static endurance of trunk muscles, reduced pain intensity, and functional disability in different age groups. No significant differences were found between groups after either 4 or 8 weeks of intervention.
Conclusion. The use of transcutaneous electrical nerve stimulation and dynamic neuromuscular stabilization may reduce back pain and functional impairment in patients with intervertebral disc degeneration, regardless the age of patients.
Keywords: transcutaneous electrical nerve stimulation, dynamic neuromuscular stabilization, back pain, disc degeneration.
Role of Traditional Chinese Medicine in Bone Regeneration and Osteoporosis
Authors: Peng Zhicai , Xu Ronghua , You Qinjian 
Published: May 2022

According to World Health Organization (WHO), osteoporosis is a systematic bone disability marked by reduced bone mass and microarchitectural degeneration of osseous cells, which leads to increased bones feebleness and fractures vulnerability. It is a polygenetic, physiological bone deformity that frequently leads to osteoporotic fractures and raises the risk of fractures in minimal trauma. Additionally, the molecular changes that cause osteoporosis are linked to decreased fracture repair and delayed bone regeneration. Bones have the ability to regenerate as part of the healing mechanism after an accident or trauma, including musculoskeletal growth and ongoing remodeling throughout adulthood. The principal treatment approaches for bone loss illnesses, such as osteoporosis, are hormone replacement therapy (HRT) and bisphosphonates. In this review, we searched literature regarding the Traditional Chinese medicines (TCM) in osteoporosis and bone regeneration. The literature results are summarized in this review for osteoporosis and bone regeneration. Traditional Chinese medicines (TCM) have grown in popularity as a result of its success in curing ailments while causing minimal adverse effects. Natural Chinese medicine has already been utilized to cure various types of orthopedic illnesses, notably osteoporosis, bone fractures and rheumatism with great success. TCM is a discipline of conventional remedy that encompasses herbal medication, massage (tui na), acupuncture, food, and exercise (qigong) therapy. It is based on more than 2,500 years of Chinese healthcare profession. This article serves as a comprehensive review summarizing the osteoporosis, bone regeneration and the traditional Chinese medicines used since ancient times for the management of osteoporosis and bone regeneration.
Influence of Colonies’ Morphological Cues on Cellular Uptake Capacity of Nanoparticles
Authors: Huang Siyuan , Su Qi , Hou Xiaoqiang , Han Kuankuan , Ma Shufang , Xu Bingshe , Yang Yingjun 
Published: May 2022

High transmembrane delivery efficiency of nanoparticles has attracted substantial interest for biomedical applications. It has been proved that the desired physicochemical properties of nanoparticles were efficient for obtaining a high cellular uptake capacity. On the other hand, biophysical stimuli from in situ microenvironment were also indicated as another essential factor in the regulation of cellular uptake capacity. Unfortunately, the influence of colony morphology on cellular uptake capacity was rarely analyzed. In this study, micropatterned PDMS stencils containing circular holes of 800/1,200 μm in diameter were applied to control colonies’ size. The amino-modified nanoparticles were cocultured with micropatterned colonies to analyze the influence of colonies’ morphology on the cellular uptake capacity of nanoparticles. Consequently, more endocytosed nanoparticles in larger colonies were related with a bigger dose of nanoparticles within a larger area. Additionally, the high cell density decreased the membrane–nanoparticles’ contacting probability but enhanced clathrin-mediated endocytosis. With these contrary effects, the cells with medium cell density or located in the peripheral region of the micropatterned colonies showed a higher cellular uptake capacity of nanoparticles.
Wavelength-Tuneable Near-Infrared Luminescence in Mixed Tin–Lead Halide Perovskites
Authors: Liu Meiyue , Zhao Ru , Sun Fuhao , Zhang Putao , Zhang Rui , Chen Zeng , Li Shengjun 
Published: May 2022

Near-infrared light-emitting diodes (NIR-LEDs) are widely used in various applications such as night-vision devices, optical communication, biological imaging and optical diagnosis. The current solution-processed high-efficiency perovskite NIR-LEDs are typically based on CsPbI3 and FAPbI3 with emission peaks being limited in the range of 700–800 nm. NIR-LEDs with longer emission wavelengths near to 900 nm can be prepared by replacing Pb with Sn. However, Sn-based perovskite LEDs usually exhibit a low efficiency owing to the high concentration of Sn-related defects and the rapid oxidation of Sn2+ to Sn4+, which further induces the device degradation. These problems can be solved by rationally adjusting the ratio between Pb content with Sn. Mixed Sn-Pb halide perovskites with a smaller bandgap and superior stability than pure Sn-based perovskites are promising candidates for manufacturing next-generation NIR emitters. In this study, we systematically investigated the optical properties of a family of hybrid Sn and Pb iodide compounds. The emission spectra of the mixed Sn-Pb halide perovskites were tuned by changing the Sn:Pb ratio. Consequently, the peak emission wavelength red-shifted from 710 nm to longer than 950 nm. The absorption and photoluminescence emission properties associated with different compositions were compared, and the results demonstrated the potential of MA- and FA-based mixed Sn-Pb halide perovskites for preparing low-cost and efficient NIR-LEDs. In addition, we clarified the influence of cations on the bandgap bowing effect and electronic properties of mixed Sn-Pb halide perovskites.
Derivative Matrix-Isopotential Synchronous Spectrofluorimetry and Hantzsch Reaction: A Direct Route to Simultaneous Determination of Urinary δ-Aminolevulinic Acid and Porphobilinogen
Authors: Ajmal Muhammad , Wei Jia-Wen , Zhao Yan , Liu Yi-Hong , Wu Ping-Ping , Li Yao-Qun 
Published: May 2022

Early and sensitive detection of δ-aminolevulinic acid (δ-ALA) and porphobilinogen (PBG) is the cornerstone of diagnosis and effective treatment for acute porphyria. However, at present, the quantifying strategies demand multiple solvent extraction steps or chromatographic approaches to separate δ-ALA and PBG prior to quantification. These methods are both time-consuming and laborious. Otherwise, in conventional spectrofluorimetry, the overlapping spectra of the two analytes cause false diagnosis. To overcome this challenge, we present a two-step approach based on derivative matrix-isopotential synchronous fluorescence spectrometry (DMISFS) and the Hantzsch reaction, realizing the simple and simultaneous detection of δ-ALA and PBG in urine samples. The first step is chemical derivatization of the analytes by Hantzsch reaction. The second step is the determination of the target analytes by combining MISFS and the first derivative technique. The proposed approach accomplishes following advantages: 1) The MISFS technique improves the spectral resolution and resolves severe spectral overlap of the analytes, alleviating tedious and complicated pre-separation processes; 2) First derivative technique removes the background interference of δ-ALA on PBG and vice versa, ensuring high sensitivity; 3) Both the analytes can be determined simultaneously via single scanning, enabling rapid detection. The obtained detection limits for δ-ALA and PBG were 0.04 μmol L−1 and 0.3 μmol L−1, respectively. Within-run precisions (intra and inter-day CVs) for both the analytes were &lt;5%. Further, this study would serve to enhance the availability of early and reliable quantitative diagnosis for acute porphyria in both scientific and clinical laboratories.
Surgical Techniques and Outcomes in Patients With Intra-Cardiac Abscesses Complicating Infective Endocarditis
Authors: Straw Sam , Baig M. Wazir , Mishra Vishal , Gillott Richard , Witte Klaus K. , Van Doorn Carin , Ferrara Antonella , Javangula Kalyana , Sandoe Jonathan A. T. 
Published: May 2022

BackgroundAn intra-cardiac abscess is a serious complication of both native (NV-IE) and prosthetic valve infective endocarditis (PV-IE). Despite being an accepted indication for surgery, controversies remain regarding the optimal timing and type of operation. We aimed to report the outcomes of patients managed for intra-cardiac abscesses over more than a decade.MethodsPatients aged ≥18 years managed for intra-cardiac abscess between 1 January 2005 and 31 December 2017 were identified from a prospectively collected IE database. The primary outcome was 30-day mortality in operated patients and secondary outcomes were freedom from re-infection, re-operation and long-term mortality comparing those patients with aortic root abscess who underwent aortic valve replacement (AVR) and those who received aortic root replacement (ARR).ResultsFifty-nine patients developed an intra-cardiac abscess, and their median age was 55 (43–71) years; among them, 44 (75%) were men, and 10 (17%) were persons who injected drugs. Infection with beta-haemolytic streptococci was associated with NV-IE (p= 0.009) and coagulase-negative staphylococci with PV-IE (p= 0.005). Forty-four (75%) underwent an operation, and among those with aortic root abscess, 27 underwent AVR and 12 ARR. Thirty-day mortality was associated with infection withS. aureus(p= 0.006) but not the type or timing of the operation. Survival in operated patients was 66% at 1 year and 59% at 5 years. In operated patients, none had a relapse, although six developed late recurrence. Freedom from infection, re-operation and long-term mortality were similar in patients undergoing AVR compared to ARR.ConclusionPatients diagnosed with intra-cardiac abscess who were not operated on had very poor survival. In those who underwent an operation, either by AVR or ARR based upon patient factors, imaging and intra-operative findings outcomes were similar.
Comparing Clinical Outcomes on Oncology Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-Analysis
Authors: Song Yumeng , Wang Yutong , Wang Zuoxiang , Xu Chang , Dou Jingshen , Jiang Tingbo 
Published: May 2022

ObjectiveTo compare the clinical outcomes of cancer and non-cancer patients with severe aortic stenosis (AS) after transcatheter aortic valve implantation (TAVI).MethodsA computer-based search in PubMed, EMbase, The Cochrane Library, CBM, CNKI, and Wanfang databases from their date of inception to October 2021, together with reference screening, was performed to identify eligible clinical trials. Two reviewers independently screened the articles, extracted data, and evaluated their quality. Review Manger 5.3 and Stata 12.0 software were used for meta-analysis.ResultsThe selected 11 cohort studies contained 182,645 patients, including 36,283 patients with cancer and 146,362 patients without cancer. The results of the meta-analysis showed that the 30-day mortality [OR = 0.68, 95%CI (0.63,0.74), I2= 0, P &lt; 0.00001] of patients with cancer in the AS group was lower than those in the non-cancer group; 1-year mortality [OR = 1.49, 95%CI(1.19,1.88), I2= 58%, P = 0.0006] and late mortality [OR = 1.52, 95%CI(1.26,1.84), I2= 55%, P &lt; 0.0001] of patients with cancer in the AS group was higher than those in the non-cancer group. The results of the meta-analysis showed that the stroke [OR = 0.77, 95%CI (0.72, 0.82), I2= 0, P &lt; 0.00001] and the acute kidney injury [OR = 0.78, 95%CI (0.68, 0.90), I2= 77%, P = 0.0005] of patients with cancer in the AS group was lower than those in the non-cancer group. The results of the meta-analysis showed no statistical difference in cardiovascular mortality, bleeding events, myocardial infarction, vascular complication, and device success rate.ConclusionIt is more effective and safer in patients with cancer with severe AS who were undergoing TAVI. However, compared with patients with no cancer, this is still high in terms of long-term mortality, and further study of the role of TAVI in patients with cancer with AS is necessary.Systematic Review RegistrationIdentifier [INPLASY CRD: 202220009].
Predictors of Recurrence and Survival in Cancer Patients With Pericardial Effusion Requiring Pericardiocentesis
Authors: Ahmed Talha , Mouhayar Elie , Song Juhee , Koutroumpakis Efstratios , Palaskas Nicolas L. , Yusuf Syed Wamique , Lopez-Mattei Juan , Hassan Saamir A. , Kim Peter , Cilingiroglu Mehmet , Marmagkiolis Konstantinos , Vaporciyan Ara A. , Swisher Stephen , Deswal Anita , Iliescu Cezar 
Published: May 2022

AimThis study investigated the factors predicting survival and the recurrence of pericardial effusion (PE) requiring pericardiocentesis (PCC) in patients with cancer.Materials and MethodsWe analyzed the data of patients who underwent PCC for large PEs from 2010 to 2020 at The University of Texas MD Anderson Cancer Center. The time to the first recurrent PE requiring PCC was the interval from the index PCC with pericardial drain placement to first recurrent PE requiring drainage (either repeated PCC or a pericardial window). Univariate and multivariate Fine-Gray models accounting for the competing risk of death were used to identify predictors of recurrent PE requiring drainage. Cox regression models were used to identify predictors of death.ResultsThe study cohort included 418 patients with index PCC and pericardial drain placement, of whom 65 (16%) had recurrent PEs requiring drainage. The cumulative incidences of recurrent PE requiring drainage at 12 and 60 months were 15.0% and 15.6%, respectively. Younger age, anti-inflammatory medication use, and solid tumors were associated with an increased risk of recurrence of PE requiring drainage, and that echocardiographic evidence of tamponade at presentation and receipt of immunotherapy were associated with a decreased risk of recurrence. Factors predicting poor survival included older age, malignant effusion on cytology, non-use of anti-inflammatory agents, non-lymphoma cancers and primary lung cancer.ConclusionAmong cancer patients with large PEs requiring drainage, young patients with solid tumors were more likely to experience recurrence, while elderly patients and those with lung cancer, malignant PE cytology, and non-use of anti-inflammatory agents showed worse survival.