bluuebunny/crossref_metadata_2025_split huggingface dataset:
We Don't Choose Whom We Love: Predictors for Romantic Attraction to Villains
Authors: Frowijn Iris , Vos Lisa M. W. , Masthoff Erik , Bogaerts Stefan 
Published: May 2022

IntroductionWhy are women (not) romantically attracted to dark personalities or villains, which might be a risk factor for intimate partner violence (IPV) victimization? In the current study, it is opted to investigate how adult attachment, maladaptive personality traits, and acceptance of couple violence in women predict romantic attraction to heroic/villainous characters using structural equation modeling (SEM).MethodFirst, a pilot study was conducted in 122 heterosexual women (aged 16–25) to select male TV characters. This resulted in the selection of six villains and 10 heroes for the main study, in which 194 other heterosexual women (aged 16–25) were asked to rate the pictures of TV characters through an online questionnaire. This was combined with self-report measures of maladaptive personality traits, acceptance of couple violence, and adult attachment. These variables were entered into a SEM model to assess model fit.ResultsOverall, women rated heroes higher on physical appearance (pilot study) and romantic attraction (main study) compared to villains. We found different direct effects of avoidant (negative) and anxious (positive) attachment styles on romantic attraction to heroes. Moreover, maladaptive personality traits fully mediated the positive effect of avoidant attachment style on romantic attraction to villains.DiscussionDespite the limitations of the study design (e.g., low N, low notoriety of the TV characters), this study emphasizes that women are generally more romantically attracted to heroes (vs. villains). Besides, there are different predictors of romantic attraction to heroes and villains, which requires further investigation, especially in the context of IPV.
Depressive, Anxiety Symptom Frequency and Related Factors Among Prisoners During the COVID-19 Pandemic in Northeastern Ethiopia, a Cross-Sectional Study
Authors: Birkie Mengesha , Necho Mogesie , Tsehay Mekonnen , Gelaye Habtam , Beyene Abeba , Belete Asmare , Asmamaw Amare , Tessema Zemenu Tadesse , Bogale Kassahun , Adane Metadel 
Published: May 2022

BackgroundAmong the more than 10 million people imprisoned around the world, the rate of mental illness is higher than among the general population for various reasons. Although rates of mental illnesses such as depression and anxiety in this population may have changed as a response to the coronavirus disease (COVID-19) outbreak and other factors, to our knowledge, no related studies have been conducted related to depression and anxiety in this population during the pandemic. Therefore, this study aimed to assess depression, anxiety, and associated factors among Dessie City prisoners during the 2020 COVID-19 outbreak.MethodsAn institution-based cross-sectional survey was conducted in October 2020. A total of 420 prisoners were selected via a systematic sampling technique. PHQ-9 depression scale, generalized anxiety disorder-7 questionnaire, Oslo 3-item social support scale, insomnia severity index, and Brief COPE scale were used. Data were entered by using Epi-Data version 3.1 and finally exported to Statistical Package for Social Science Software version 21 for analysis. We fitted a multiple binary logistic regression model. Finally, an adjusted odds ratio with 95% confidence interval was reported and factors with a p-value &lt; 0.05 were considered as significant for depression and anxiety.ResultsThis study showed that 279 (66.4%) of imprisoned people had major depressive disorder with 95% CI of (61.4, 70.6), while 281 (66.9) had generalized anxiety disorder with 95% CI of (61.9, 71.9).ConclusionIn this study, the overall prevalence of depression and anxiety was significantly high, and was related to a number of factors including COVID-19. Therefore, designing and implementing strategies for COVID-19 prevention and control in prisons is highly recommended to reduce mental health problems among prisoners.
COVID-19 Pandemic in Dialysis Patients: The Swiss Experience
Authors: Guidotti Rebecca , Pruijm Menno , Ambühl Patrice M. 
Published: May 2022

BackgroundChronic dialysis patients are classified as patients with increased risk for COVID-19. Knowledge about the incidence and survival of chronic dialysis patients infected with SARS-CoV-2 in Switzerland - a high-income country with high density of relatively small dialysis centers - is scarce. We present the findings regarding incidence, survival and regional differences, compared to those of the general population in Switzerland.MethodsInformation on chronic dialysis patients who tested positive for SARS-CoV-2 between February 24, 2020 and February 28, 2022 were reported to the Swiss dialysis registry by all 94 Swiss dialysis centers. Hereafter, these results were linked with clinical characteristics from the Swiss dialysis registry.ResultsThroughout the study period 1,120 out of ~4,700 dialysis patients tested positive for SARS-CoV-2 in Switzerland: 96 cases occurred in the first wave, 472 in the second wave and 5 in between. During the first wave, Italian-speaking Ticino was most severely affected, with a 7-fold higher incidence of dialysis patients compared to the general Swiss population. In the second wave, the majority of cases were found in the French-speaking part of Switzerland, with a 2.5 times higher incidence vs. non-dialysis patients. A total of 123 deaths were recorded in the first two waves, of which COVID-19 was the main cause of death in 100 patients. This corresponds to a highly increased overall mortality rate of 17.5% compared to 1.7% in the general population. Age was identified as the only risk factor for mortality in dialysis patients. During the third, fourth and fifth wave, 61, 43 and 443 cases, respectively, were recorded, resulting in 6 (mortality rate 9.8%), 1 (mortality rate 2.3%) and 13 deaths (mortality rate 2.9%).ConclusionChronic dialysis patients in Switzerland were more likely to be infected by SARS-CoV-2 during the first and second wave than the rest of the population, but an inverse trend was observed during the third, fourth and fifth wave, probably thanks to vaccination. In addition, mortality is significantly increased compared to non-dialysis patients. In Swiss dialysis patients, age is the strongest risk factor for death.
Incidence, Risk Factors and Outcomes of Sepsis in Critically Ill Post-craniotomy Patients: A Single-Center Prospective Cohort Study
Authors: Zhou Jianfang , Luo Xu-Ying , Chen Guang-Qiang , Li Hong-Liang , Xu Ming , Liu Shuai , Yang Yan-Lin , Shi Guangzhi , Zhou Jian-Xin , Zhang Linlin 
Published: May 2022

BackgroundData concerning the epidemiology of sepsis in critically ill post-craniotomy patients are scarce. This study aimed to assess the incidence, risk factors, and outcomes of sepsis in this population.MethodsThis was a single-center prospective cohort study. Post-craniotomy patients admitted to the intensive care unit (ICU) were screened daily for the presence of infection and sepsis.ResultsOf the 900 included patients, 300 developed sepsis. The cumulative incidence of sepsis was 33.3% [95% confidence interval (CI), 30.2–36.4%]. Advanced age, male, hypertension, trauma, postoperative intracranial complications, and lower Glasgow Coma Scale (GCS) on the first postoperative day were independent risk factors of sepsis. Septic patients had higher hospital mortality (13.7 vs. 8.3%, P = 0.012), longer ICU length of stay (LOS) (14 vs. 4 days, P &lt; 0.001), longer hospital LOS (31 vs. 19 days, P &lt; 0.001), and higher total medical cost (CNY 138,394 vs. 75,918, P &lt; 0.001) than patients without sepsis.ConclusionSepsis is a frequent complication in critically ill post-craniotomy patients. Advanced age, male, hypertension, trauma, postoperative intracranial complications, and lower GCS on the first postoperative day were independent risk factors of sepsis.
m6A Regulator-Mediated Methylation Modification Patterns and Characteristics in COVID-19 Patients
Authors: Qing Xin , Chen Qian , Wang Ke 
Published: May 2022

BackgroundRNA N6-methyladenosine (m6A) regulators may be necessary for diverse viral infectious diseases, and serve pivotal roles in various physiological functions. However, the potential roles of m6A regulators in coronavirus disease 2019 (COVID-19) remain unclear.MethodsThe gene expression profile of patients with or without COVID-19 was acquired from Gene Expression Omnibus (GEO) database, and bioinformatics analysis of differentially expressed genes was conducted. Random forest modal and nomogram were established to predict the occurrence of COVID-19. Afterward, the consensus clustering method was utilized to establish two different m6A subtypes, and associations between subtypes and immunity were explored.ResultsBased on the transcriptional data from GSE157103, we observed that the m6A modification level was markedly enriched in the COVID-19 patients than those in the non-COVID-19 patients. And 18 essential m6A regulators were identified with differential analysis between patients with or without COVID-19. The random forest model was utilized to determine 8 optimal m6A regulators for predicting the emergence of COVID-19. We then established a nomogram based on these regulators, and its predictive reliability was validated by decision curve analysis. The consensus clustering algorithm was conducted to categorize COVID-19 patients into two m6A subtypes from the identified m6A regulators. The patients in cluster A were correlated with activated T-cell functions and may have a superior prognosis.ConclusionsCollectively, m6A regulators may be involved in the prevalence of COVID-19 patients. Our exploration of m6A subtypes may benefit the development of subsequent treatment modalities for COVID-19.
Monitoring the Impact of Rapid Urbanization on Land Surface Temperature and Assessment of Surface Urban Heat Island Using Landsat in Megacity (Lahore) of Pakistan
Authors: Farid Nasir , Moazzam Muhammad Farhan Ul , Ahmad Sajid Rashid , Coluzzi Rosa , Lanfredi Maria 
Published: May 2022

The present study focused on rapid urbanization due to the change in the existing landforms which has caused substantial adverse impacts on Urban Thermal Environment. In the present study, we have acquired the Landsat data (TM and OLI) for the years 1990, 2000, 2010, and 2020 to observe the land use changes (vegetation cover, built up land, barren land, and water) in Lahore using the supervised image classification method. Later, the impact of urbanization has been examined with Land Surface Temperature (LST) and eventually the Surface Urban Heat Island (SUHI) has been calculated. Accuracy of the classified images revealed an overall accuracy (Kappa co-efficient) of 95.3% (0.929%), 92.05% (0.870%), 89.7% (0.891%), and 85.8% (0.915%) for the years 1990, 2000, 2010, and 2020, respectively. It was found that vegetation cover decreased from 60.5% in 1990 to 47.7% in 2020 at the cost of urbanization. The overall built-up land increased by 23.52% from 1990 to 2020. Urbanization has influenced the LST, and it was examined that maximum LST consistently increased with increase in built-up land. The difference between urban and rural buffer reveals that SUHI has also been increasing over the years. SUHI has been raised from 1.72 C in 1990 to 2.41 C in 2020, and about 0.69 C relative change has been observed. It has also been observed that the Normalized Difference Vegetation Index (NDVI) and LST have an inverse relationship. The research outcomes of this study are useful for urban climatologists, urban planners, architects, and policymakers to devise climate resilient policies, structure, and decisions to balance the urban green spaces for a healthy urban environment.
The Effect of Kangaroo Mother Care After Duodenal Obstruction in Neonates
Authors: Zhu Li-Bo , Xu Yan-Hua , Li Jin-Fen , Hu Xue , Lu Chun-Yan , Li Rui-Lan , Shi Cai-Ping , Yuan Mei 
Published: May 2022

ObjectiveThe present study aimed to explore the effectiveness of clinical application of kangaroo mother care (KMC) in neonates after surgery for duodenal obstruction in achieving total enteral nutrition (TEN) and shortening the length of hospital stay.MethodsA prospective study of 60 cases of surgery for duodenal obstruction in pediatric patients in the neonatal intensive care unit of Kunming Children's Hospital between January 2018 and December 2019 was conducted. The study subjects included 15 cases with intestinal malrotation, 18 cases with circular pancreas, 10 cases with a duodenal septum, and 17 cases with duodenal atresia or duodenal stenosis. According to the single and double numbers of the operation date, the subjects were randomly divided into the control group and observation group, with 30 cases in each group. The conventional care of enhanced recovery after surgery (ERAS) was carried out in the control group, and KMC based on ERAS conventional care was implemented in the observation group. The difference in the duration to achieve TEN and the length of hospital stay between the two groups of patients after care was compared and analyzed.ResultsThe average duration to achieve TEN for neonates with duodenal obstruction in the control group was 14.23 ± 3.17 days, while that in the observation group was 12.27 ± 1.15 days. The average length of hospital stay in the control group was 17.22 ± 4.71 days, while that in the observation group was 13.34 ± 2.70 days. There was a significant difference in the duration to achieve TEN and the average length of hospital stay between the two groups (P &lt; 0.05). The duration to achieve TEN and the length of hospital stay in pediatric patients were significantly shorter in the observation group than in the control group.ConclusionKangaroo mother care has important clinical significance and application value in shortening the duration to achieve TEN and the length of hospital stay in neonates after surgery for duodenal obstruction.
Long Non-Coding RNA MAFG-AS1 as a Potential Biomarker for Hepatocellular Carcinoma: Linkage with Tumor Features, Markers, Liver Functions, and Survival Profile
Authors: Tian Yuanyuan , Wang Jiao , Tian Ge , Li Bing , Chen Moli , Sun Xiaoning 
Published: May 2022

PurposeLong non-coding RNAs musculoaponeurotic fibrosarcoma oncogene family, protein G antisense 1 (lnc-MAFG-AS1) regulates hepatocellular carcinoma (HCC) progression and treatment resistance in multiple ways, while its engagement in HCC clinical management remains obscure. The current study aims to explore the relationship of lnc-MAFG-AS1 with tumor features, liver function indexes, tumor markers, and prognosis in HCC patients.MethodsOne hundred and fifty-two surgical HCC patients who underwent tumor resection were retrospectively analyzed. Their tumor and adjacent tissues were acquired and then proposed to reverse transcription-quantitative polymerase chain reaction to detect lnc-MAFG-AS1 expression.ResultsLnc-MAFG-AS1 expression was increased in HCC tumor tissue than in adjacent tissue [median (interquartile range): 2.730 (1.685–4.198) vs. 0.990 (0.703–1.468), p &lt; 0.001], with a high area under the curve [0.889, 95% confidence interval (CI): 0.854–0.924] to distinguish them via receiver operating characteristic curve analysis. Tumor lnc-MAFG-AS1 was linked with multifocal nodules (p &lt; 0.001), increased Barcelona Clinic Liver Cancer (BCLC) stage (p = 0.018), and elevated China Liver Cancer (CNLC) stage (p = 0.008), which also correlated with an abnormal alpha-fetoprotein (AFP) level (p = 0.004), However, lnc-MAFG-AS1 was not linked with other disease conditions, tumor properties, liver function indexes, or tumor markers (all ps &gt; 0.05). In addition, patients with a high expression of lnc-MAFG-AS1 exhibited worse overall survival than those with a low expression of lnc-MAFG-AS1 [median (95% CI): 34.0 (24.5–43.5) vs. 48.0 (41.5–54.5) months] (p = 0.011), which was further validated by univariate Cox’s analysis [hazard ratio (HR) = 1.827, p = 0.013] and multivariate Cox’s analysis (HR = 1.697, p = 0.040).ConclusionLnc-MAFG-AS1 relates to multifocal nodules, increased BCLC stage, elevated CNLC stage, and abnormal AFP level and predicts pejorative prognosis in HCC patients.
Efficacy and Safety of Prostatic Artery Embolization in the Treatment of High Risk Benign Prostatic Hyperplasia and its Influence on Postoperative Life Quality of Patients
Authors: Wang Kun , Chen Ming , Liu Yiqing , Xiao Weiren , Qian Yonghong , Liu Xu 
Published: May 2022

ObjectiveTo evaluate the efficacy, safety and postoperative quality of life of high risk benign prostatic hyperplasia (BPH) patients treated with prostatic artery embolization.Methods34 patients with high-risk BPH were selectedfrom January 2020 to June 2021 in our hospital. All patients were treated with prostatic artery embolization. The changes of international prostate symptom score (IPSS), prostate volume (PV), remaining urine (RU), maximum urine flow rate (Qmax), quality of life scale -74(GQOLI-74), time to sleep without disturbance (HUS) judgment, self-rating anxiety scale (SAS) score and self-rating depression scale (SDS) were compared before operation, 1 month and 6 months after operation.ResultsProstatic artery embolization was successful in all 34 patients, including unilateral embolization in 15 patients and bilateral embolization in 19 patients. No severe complications occurred in the postoperative patients. The IPSS, PV and RU levels of the patient one month and six months after surgery were lower than those before surgery, while the Qmax level was higher than that before surgery. Besides, the IPSS, PV and RU levels six months after surgery were significantly lower than those one month after surgery, and the Qmax level was significantly higher than that one month after surgery (p &lt; 0.05). The GQOLI-74 score six months after surgery was significantly higher than that before surgery (p &lt; 0.05). The HUS of the patient six months after surgery was significantly increased, and the SAS and SDS scores were significantly decreased as compared with those before surgery (p &lt; 0.05).ConclusionFor high-risk patients with BPH, prostate embolization is an effective and safe method, which can significantly improve the quality of life of patients after surgery and has good application prospects.
Association of all Cause and Cause-Specific Mortality With Hearing Loss Among US Adults: A Secondary Analysis Study
Authors: Cui Yiran , Yan Yan 
Published: May 2022

Objectives: Previous research revealed the relationship between hearing loss (HL) and all cause mortality. The aim of this study was to determine the association between HL and all causes and cause-specific mortality based on US adults.Methods: Data were obtained by linking National Health Interview Survey (NHIS) (2004–2013) with linkage to a mortality database to 31 December 2015. HL were categorized into four groups: good hearing, a little hearing difficulty, a lot of hearing difficulty, profoundly deaf. The relationship between HL and mortality risk was analyzed using Cox proportional hazards regression model.Results: Compared with the reference group (Good), those who had light or moderate hearing problems were at an increased risk of mortality for all causes (A little trouble—HR: 1.17; 95% confidence interval [CI]: 1.13 to 1.20; A lot of trouble—HR: 1.45; 95% CI: 1.40–1.51); deaf—HR: 1.54; 95% CI: 1.38–1.73) respectively.Conclusion: In addition, those in the deaf category have the highest risk of death from all causes and cause-specific cancer. More older adults are associated with an increased risk of all-cause mortality in American adults.
MANUFACTURED OF LOTION FROM AVOCADO LEAF ETHANOL EXTRACT ( PERSEA AMERICANA MILL) AS SKIN MOISTURIZER
Authors: Br Manik Margaretta Olivia , Mahmiara Nopri 
Published: May 2022

Abstrak
Alpukat diformulasikan menjadi lotion, berdasarkan penelitian sebelumnya daun nya mengandung antioksidan tinggi yang diwakili dengan senyawa flavonoid. Tujuannya untuk mengetahui sediaan dari ekstrak etanol daun alpukat dapat melembabkan kulit.
Penelitian ini dengan metode eksperimen. Ekstrak daun alpukat dilakukan dengan proses maserasi. Pemeriksaan sediaan dilakukan pada penelitian ini adalah uji skrining fitokimia, uji Ph, uji iritasi dan uji kelembapan kulit dengan konsentrasi 3% dan 5%.

Abstract
Avocado is formulated into a lotion, based on previous research, its leaves contain high antioxidants which are represented by flavonoid coumpounds . The aim was to determine whether the preparation of avocado leaf ethanol extract could moisturerize the skin.
This research uses the experimental method. Leaf was carried out by a maceration process. Examination of the preparation carried out in this study were phytochemical screening tests, pH, Irritation and skin moisture with concentration of 3% and 5%.
PENGARUH PREGNANCY MASSAGE PUNGGUNG TERHADAP NYERI PUNGGUNG IBU HAMIL TM III
Authors: Pangesti Christiani Bumi , Puji Astuti Hutari , Eka cahyaningtyas Martina 
Published: May 2022

ABSTRAK.
Ketidaknyamanan sering terjadi pada ibu hamil TM III yaitu salah satunya adalah nyeri pada punggung. Sekitar 80% wanita mengalami nyeri pada punggungnya di beberapa titik selama kehamilan. Hal ini terjadi 70% akibat perubahan otot tulang punggung, sedangkan 30% nya mungkin bisa disebabkan karena masalah pada kondisi tulang belakang sebelumnya. Pemijatan juga bertujuan untuk mengembalikan aliran vena dan getah bening, menstimulasi reseptor sensorik pada kulit dan sub kulit untuk mengurangi rasa nyeri. Studi pendahuluan yang dilakukan di Samudra Mom Kids SPA Kabupaten Sragen pada bulan Februari 2021 terdapat 10 ibu hamil yang dilakukan wawacancara menyatakan 8 (80%) ibu hamil mengeluh nyeri punggung pada saat Trimester III. Tujuan penelitian ini untuk mengetahui Pengaruh Pregnancy Massage Punggung Terhadap Nyeri Punggung Ibu Hamil. Metode penelitian ini menggunakan quasy experiment dengan rancangan non randomized pretest and posttest with control group design. Penelitian ini dilakukan selama 3 bulan, pada bulan April sampai dengan Juni 2021. Pengambilan sampel dilakukan secara non ramdom sampling dengan teknik purposive sampling. Analisis data menggunakan uji Mann-Whitney. Hasil ada pengaruh yang signifikan dari pemberian pregnancy massage pada punggung terhadap nyeri punggung ibu hamil Trimester III di Samudra Mom Kids SPA Kabupaten Sragen yang dibuktikan dengan nilai probabilitas (p) 0,043 < 0,05.