bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advances in percutaneous renal puncture: a comprehensive review of the literature
Authors: Tatanis Vasileios , Cracco Cecilia Maria , Liatsikos Evangelos 
Published: October 2022

Purpose of review
Percutaneous nephrolithotomy (PCNL) constitutes the gold standard procedure for patients suffering from more than 2 cm renal stones. The puncture is a very critical step of PCNL, affecting manoeuvrability of the nephroscope, possibility to remove stone fragments, risk of bleeding and radiation exposure. The aim of the current review was to discuss the advances in percutaneous renal puncture.

Recent findings
Following technological evolution in medicine, there was a consistent development in the puncture techniques, aiming at the improvement of its efficacy and safety. The use of specific agents can improve ultrasonic guidance, making the challenging step of gaining access to the kidney easier for the experienced surgeon and more accessible for the resident urologist. Future developments in the electromagnetic and three-dimensional (3D) technology may establish a high level of accuracy with decreased rates of related complications, even in the hands of beginners.

Summary
The advances in percutaneous puncture can lead to improved safety and accuracy of this procedure decreasing the radiation exposure and the complication rate.
Adalimumab Therapy in Pediatric Crohn Disease: A 2-Year Follow-Up Comparing “Top-Down” and “Step-Up” Strategies
Authors: Payen Elise , Neuraz Antoine , Zenzeri Letizia , Talbotec Cécile , Abi Nader Elie , Chatenoud Lucienne , Chhun Stephanie , Goulet Olivier , Ruemmele Frank M. , Pigneur Bénédicte 
Published: October 2022

Objectives:
European Crohn’s Colitis Organization (ECCO) and the European Society of Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidelines recommend the early use of anti-tumor necrosis factor (TNF) biologicals in pediatric Crohn disease (CD) patients with positive predictors for poor outcome. The objective of the present study was to compare early “Top-Down” use of adalimumab (ADA) immunomodulator/biologics-naive patients to conventional “Step-Up” management.

Methods:
One hundred and twenty consecutive patients with a confirmed diagnosis of CD and treated with ADA between 2008 and 2019 were included and allocated to the ADA-Top Down (n = 59) or ADA-Step Up group (n = 61). The primary endpoint was prolonged steroid-/enteral nutrition-free clinical remission at 24 months, defined by a weighted Pediatric Crohn’s Disease Activity Index (wPCDAI) < 12.5. Clinical and biological data were collected at 12 and 24 months.

Results:
At start of ADA, disease activity was comparable between the ADA-Top Down group and the ADA-Step Up group (wPCDAI = 31 ± 16 vs 31.3 ± 15.2, respectively, P = 0.84). At 24 months, the remission rate was significantly higher in the ADA-Top Down group (73% vs 51%, P < 0.01). After propensity score, the Top-Down strategy is still more effective than the Step-Up strategy in maintaining remission at 24 months [hazard ratio (HR) = 0.36, 95% CI (0.15–0.87), P = 0.02]. Patients in the ADA-Top Down group were mainly on monotherapy compared to patients in the ADA-Step Up group (53/55 vs 28/55 respectively, P < 0.001). Serum levels of ADA were higher in the ADA-Top Down group than in the ADA-Step Up group (12.8 ± 4.3 vs 10.4 ± 3.9 µg/mL, respectively, P < 0.01). There were no serious adverse events.

Conclusions:
Early use of ADA appears to be more effective in maintaining relapse-free remission at 2 years, while using it as monotherapy. These findings further favor the recommendation of early anti-TNF use in high-risk CD patients.
Need for a primary care–based intervention for fear of cancer recurrence: conclusions from the BLANKET trial
Authors: Luigjes-Huizer Yvonne L. , Helsper Charles W. , Gerrits Marloes M. J. G. , de Wit Niek , van der Lee Marije L. 
Published: October 2022

Abstract

Background:
More than half of cancer survivors experience fear of cancer recurrence (FCR). There has been a call for easily accessible, inexpensive interventions for moderate FCR to complement existing specialized care. In the randomized BLANKET trial, we investigated the effectiveness of a short, primary care intervention for FCR. We report on the potential of the intervention and the suitability of primary care to offer this intervention.

Methods:
The BLANKET trial is a cluster randomized controlled trial with change in FCR severity (severity subscale of the Fear of Cancer Recurrence Inventory) as its main outcome. Participating general practitioners invited all patients who completed successful curative cancer treatment between 3 months and 10 years ago. We report effect measures, outcome of our recruitment strategy, intervention uptake, reasons not to participate, and experiences with the intervention.

Results:
Sixty-two of 1368 (4.5%) invited cancer survivors participated. Main reported reasons not to participate were not experiencing FCR and not wanting help. Owing to the low participation, we could not robustly evaluate the intervention's effectiveness. Indicatively, in the intention-to-treat analysis, FCR severity decreased from T0 to T1 by 2.7 points (standard deviation [SD] = 4.7) in the intervention group (n = 27) and 1.8 points (SD = 3.6) in the control group (n = 18). In the per-protocol analysis, the decreases were 3.5 points (SD = 4.5) and 0.7 points (SD = 2.7), respectively.

Conclusion:
Although the prevalence of FCR and the need for help for FCR are high according to the literature, the uptake of our primary care–based intervention was low. Although the intervention shows potential, alternative delivery routes need to be explored because of the low number of patients who need help for FCR per primary care practice. We recommend additional research on the impact of FCR, on which patients require and desire help, and on what kind of intervention and setting are fitting for what patients.
Serum Concentration of Continuously administered Vancomycin influences Efficacy and Safety in Critically Ill Adults: A Systematic Review
Authors: Viertel Katrin , Feles Elisabeth , Schulte Melanie , Annecke Thorsten , Mattner Frauke 
Published: October 2022

AbstractVancomycin is an antibiotic to treat gram-positive infections in critically ill adults. For continuously administered vancomycin (CI), various target ranges have been used in the past, ranging from 15-20 mg/L to 30-40 mg/L. This systematic literature review was conducted to investigate the impact of steady-state serum concentration (Css) of CI on the safety and efficacy of therapy in critically ill adults. According to the PRISMA statement, relevant literature was identified by searching two electronic databases (PubMed, Cochrane Library) and Google Scholar from inception until July 2023, focussing on studies reporting measured Css and treatment outcomes (e.g. mortality, nephrotoxicity) with CI. Due to the heterogeneity of the studies, a narrative synthesis of the evidence was performed. Twenty-one publications were included with a total of 2,949 patients with CI (pts). Mortality was higher (two studies, n=388 pts) and clinical cure lower (one study, n=40 pts) with a Css <15 mg/L measured 24 hours after initiation of CI (C24). An adequate loading dose appeared most important for maintaining higher C24. Generally, higher Css were associated with higher rates of acute kidney injury (AKI) (fifteen studies, n=2,331 pts). We calculated that a Css <25 mg/L (vs. ≥25 mg/L) was preferable for reducing nephrotoxicity (three studies, n=515 pts). Despite sparse data availability, the target range of 15-25 mg/L in CI may increase clinical cure and reduce mortality and AKI. In future research, vancomycin Css cohorts should be formed to allow evaluation of the impact of Css of CI on treatment outcomes.
Philosophy Spirituality and Recovery of Mental Health Nursing: Literatur Review
Authors: Sawab  , Rumambo Pandin Moses Glorino , Yusuf Ah 
Published: October 2022

AbstractBackgroundThe recurrence rate and quality of life for mental disorders are still quite low. The phenomenon of mental recovery is still focused on clinical recovery, which emphasizes drug therapy. On the other hand, empowering the patient to be able to control themselves to get a meaningful life from their illness becomes a challenge. Mental health nursing focuses on the well-being of individuals so that they have a good quality of life. Spirituality-based psychological management helps patients with mental disorders to have self-awareness, self-efficacy, self-empowerment and to create meaningful life as an important intervention in addition to drug administration. This literature review aims to explore the influence of spirituality on mental health recovery.MethodsThis study used a literature review design with four databases: Scopus, Science Direct, ProQuest, and SpringerLink. There were 12 reviewed articles published in 2019-2022. Keywords used are 1) spirituality or religiosity AND recovery AND mental illness. 2) spirituality or religiosity AND recovery AND severe mental disorder. Protocol and literature review evaluation use PRISMA.ResultsSpirituality helps mental disorder patients to build self-confidence, control themselves, find strength and build hope to find the meaning of their life. The ability to control themselves and find the meaning of their life becomes psychological well-being that will be able to improve the quality of life.ConclusionRecovery from mental disorders is complex and multifactorial; therefore, psychological interventions are constantly being developed. Psychological interventions using spirituality by involving sufferers, nurses, families, religious leaders, and other health teams need to be developed.
CRISPR/Cas12a assisted specific detection of monkeypox virus
Authors: Singh Mandeep , Misra Chitra Seetharam , Bindal Gargi , Rangu Shyam Sunder , Rath Devashish 
Published: October 2022

AbstractObjectiveTo identify monkeypox-specific sequence and distinguish it from related orthopoxviruses followed by development of a CRISPR-Cas12a-based, specific and sensitive detection of monkeypox virus.MethodsA common detection mixture (CDM) was constituted comprising of CRISPR RNAs (crRNAs) for general orthopoxviruses and monkeypox virus-specific targets along with LbCas12a and fluorescent reporter. Recombinase polymerase amplification (RPA) of target loci was carried out followed by detection using the CRISPR-Cas12 CDM complex. Fluorescence-based read out can be monitored by a fluorescent reader and alternatively can also be visualized under a blue light illuminator by naked eye.ResultsMonkeypox-specific conserved sequences were identified inpolAgene which differ by a single nucleotide polymorphism (SNP) from all the viruses present in genus Orthopoxvirus. Our Cas12a-based assay was capable of specifically distinguishing monkeypox virus from other related orthopoxviruses with an LOD of 60 copies in 1 hour after the initiation of the reaction.ConclusionOur assay exhibits sensitive and specific detection of monkeypox virus which can prove to be of practical value for surveillance in areas infected with multiple orthopoxviruses, especially in hotspots of monkeypox virus infections.
The prevalence and developmental course of auditory processing differences in autistic children
Authors: Lau Bonnie K. , Emmons Katherine A. , Lee Adrian K.C. , Munson Jeff , Dager Stephen R. , Estes Annette M. 
Published: October 2022

ABSTRACTAuditory processing differences, including hyper- or hyposensitivity to sound, aversions to sound, and difficulty listening under noisy, real-world conditions, are commonly reported in autistic individuals. However, the developmental course and functional impact of these auditory processing differences are unclear. In this study, we investigate the prevalence, developmental trajectory, and functional impact of reported auditory processing differences in autistic children throughout childhood using a longitudinal study design. Auditory processing differences were measured using the Short Sensory Profile, a caregiver questionnaire, in addition to adaptive behaviors and disruptive/concerning behaviors at 3, 6, and 9 years of age. Our results showed that auditory processing differences were reported in greater than 70% of the autistic children in our sample at all three timepoints, maintained a high prevalence through 9 years of age, and were associated with increased disruptive/concerning behaviors and difficulty with adaptive behaviors. Furthermore, in our sample of children, auditory processing differences at age 3 years predicted disruptive/concerning behaviors, difficulty with adaptive behaviors, and autism symptom severity at age 9 years. These findings warrant further investigations of the potential benefit of incorporating measures of auditory processing during routine clinical evaluations as well as interventions targeting auditory processing differences in autistic children.LAY SUMMARYWe followed a cohort of autistic children longitudinally at 3, 6, and 9 years of age and found that more than 70% of the children had reported hyper- or hypo-sensitivity to sound, sound aversions, or difficulty listening in noisy environments at all three ages. These auditory processing differences were associated with increased hyperactivity and agitation, autism symptom severity, as well as difficulty with daily living skills, suggesting that auditory processing differences should be considered during routine clinical evaluations.
T1K: efficient and accurate KIR and HLA genotyping with next-generation sequencing data
Authors: Song Li , Bai Gali , Liu X. Shirley , Li Bo , Li Heng 
Published: October 2022

AbstractKiller immunoglobulin-like receptor (KIR) genes and human leukocyte antigen (HLA) genes are highly polymorphic in a population and play important roles in innate and adaptive immunity. We have developed a novel computational method T1K that can efficiently and accurately infer the KIR or HLA alleles from next-generation sequencing data. T1K is flexible and is compatible with various sequencing platforms including RNA-seq and genomic sequencing data. We applied T1K on CD8+ T cell single-cell RNA-seq data, and identified that KIR2DL4 allele expression levels were enriched in tumor-specific CD8+ T cells.
Examination of survival strategies of quantity surveying firms amid COVID-19 pandemic disruption in Lagos State, Nigeria
Authors: Olatunde Nathaniel Ayinde , Gento Municio Angel Manuel , Awodele Imoleayo Abraham 
Published: October 2022

PurposeDisruption caused by coronavirus disease 2019 (COVID-19) to the ways and manners businesses are conducted worldwide is phenomenon. The study therefore examined the survival strategies adopted by quantity surveying firms (QSFs) in Lagos State, Nigeria, with the intention of improving their performance.Design/methodology/approachThis study used a systematic sampling method to select three QSFs from 20 local government areas in the state. Of the 60 QSFs contacted for interview, only 42 agreed to participate. A questionnaire was designed to collect the required qualitative information, which was then analyzed using content analysis.FindingsThe results revealed that the main survival strategies adopted by QSFs in Lagos State, Nigeria, during the COVID-19 disruptions were downsizing, contract staffing, salary cuts, work from home and service negotiation strategies.Research limitations/implicationsDue to the chosen research approach, the research results may not be generalizable. The incidence of the pandemic and the socio-economic situation of the study area have to be considered.Practical implicationsThe survival strategies employed by QSFs in Lagos Nigeria in the middle of COVID-19 are palliative (unsustainable) as the impact of the disruptions is biting hard on QSFs in Lagos Nigeria as such a more robust and sustainable method to enhance the performance of QSFs in the study area.Originality/valueThis study attempted to unearth the survival strategies of QSFs amidst COVID-19 in Lagos State, Nigeria, with the aim of improving the performance of such firms.
Green maritime practices in an emerging economy towards the achievement of sustainable development: a Ghanaian context
Authors: Essel Dacosta , Jin Zhihong , Bowers Joseph Oliver , Abdul-Salam Rafiatu 
Published: October 2022

PurposeThe objective to achieve economic growth and sustainable development (SD) within the maritime industry has ever since been the ultimate goal of the International Maritime Organization and its stakeholders. Coupled with this effect, the United Nations organization has also mandated all its bodies to adopt sustainable working policies and practices towards the achievement of SD in its 2030 Agenda. From the standpoint of an emerging economy, this study aims to examine green maritime practices adopted by maritime authorities towards the achievement of SD in the maritime industry of Ghana. The proposed conceptual model of this study supports the natural resource-based view theory advocated by Hart (1995).Design/methodology/approachThe dataset of this study was gathered using semi-structured questionnaires. A total of 635 valid responses were received as feedback which were tested and analyzed using partial least square structural equation modelling. The rationale for the adoption of this analytical tool is its resilient ability to handle a relatively small quantity of datasets. It is also suitable for empirical studies involving model development and at the early stage of theory development.FindingsThe findings of the study are as follows; firstly, quality maritime education and training directly and significantly influence green maritime transport (GMT), clean ocean and maritime resource conservation (COMRC), green port operations and services (GPOS), SD and waste management and treatment systems (WMTS). Secondly, GMT, COMRC, GPOS and WMTS have a direct significant influence on SD. Lastly, GMT, COMRC, GPOS and WMTS partially mediate the relationship between quality maritime education and training and SD.Practical implicationsThis study proposes a conceptual model that attempts to explain to maritime authorities and stakeholders that although the adoption of green maritime practices significantly influences SD, yet, it may be insufficient without quality maritime education and training provided to maritime professionals. Hence, emphasizing that all maritime personnel receive quality maritime education and training to enhance the long-term achievement of SD in the maritime industry. It also attempts to prove and suggest to maritime authorities how they can collectively integrate both onshore and offshore green maritime practices to achieve SD.Originality/valueThe originality of this study shows in testing a conceptual model that affirms that, achieving SD in the maritime industry is dependent on quality maritime education and training received by maritime personnel, hence, demonstrating the significant role of maritime training institutions towards the maritime industry and the achievement of SD.
New design of electric vehicle motor based on high-strength soft magnetic materials
Authors: Li Yulin , Wang Jiabao , Zhang Hang , Pei Ruilin 
Published: October 2022

Purpose
The purpose of the paper is to make a high speed motor based on the characteristics of high strength silicon steel. With the higher requirements for torque density and power density of the driving system of electric vehicles (EV), conventional magnetic materials have been difficult to meet the demands in the future. In this paper, a new type of high-strength non-grain-oriented (NGO)material is tested.

Design/methodology/approach
Through analyzing the characteristic of high strength silicon steel, it is applied to the rotor part of a high-speed motor. A topological optimization is applied to achieve higher power density and higher efficiency of the motor.

Findings
The feasibility of the scheme was analyzed by the finite element method, and a prototype was also fabricated to verify the analysis.

Originality/value
In this paper, the characteristics of new soft magnetic materials as a breakthrough to manufacture a new generation of high-performance electrical machine (EM) are discussed. Consequently, the presented work greatly facilitates further explorations and guides the innovative application of soft magnetic materials and the iterative optimization of motor structure.
Purchase decision making of garage equipment using an integrated fuzzy AHP and grey relation analysis method
Authors: James Ajith Tom , Asjad Mohammad , Panchal Rahul 
Published: October 2022

PurposeAutomobile maintenance garages require varieties of equipment for their smooth functioning. However, the purchase of the right equipment from alternatives is a tough task as it depends on several economic, technical, and environmental considerations, etc. Moreover, there are different sellers for such equipment, whose features would be satisfying the purchase criteria in varying levels or degrees. Hence, this purchase decision becomes a complex decision-making problem.Design/methodology/approachAn integrated multi-criteria decision-making approach that includes the combination of fuzzy AHP (analytic hierarchy process) and GRA (grey relational analysis) is used for the purchase decision-making of garage equipment. Various purchase decision criteria regarding garage equipment are assimilated through literature and interaction with garage professionals. The weightage of each purchase criteria of garage equipment is derived using fuzzy AHP. After the establishment of weights, various equipment suppliers are evaluated according to their conformance to the criteria using the GRA method.FindingsThe methodology of FAHP helped in ranking the different purchasing criteria based on their importance. It follows the following sequence: cost of ownership, technical specifications, operational characteristics, reliability and maintenance, after-sales support, commercial features, environmental pollution, and end of life characteristics. GRA methodology has been applied for the purchase of the best common rail test bench among alternatives according to their fulfillment of the purchase criteria requirements that are evaluated by a team of experts.Originality/valueThe integrated approach developed in this work for garage equipment purchase will help garage management to prioritize each supplier of the equipment based on their level of conformance to the purchase criteria.