bluuebunny/crossref_metadata_2025_split huggingface dataset:
Isokinetic Leg-Press Power–Force–Velocity Profiles Are Reliable in Male and Female Elite Athletes but Not Interchangeable With Vertical Jump Profiles
Authors: Fessl Isabella , Dirnberger Johannes , Kröll Josef , Wiesinger Hans-Peter 
Published: August 2022

Purpose: To evaluate the test–retest reliability of isokinetic leg-press power–force–velocity profile (P–F–v) parameters in male and female elite athletes. In addition, we determined the concurrent validity of leg-press against squat-jump (SJ) P–F–v parameters in task-experienced athletes. Methods: For test–retest reliability, 22 female and 23 male elite athletes (22.3 [4.1] y) with different sporting backgrounds conducted 3 isokinetic leg-press test sessions over 3 consecutive weeks. The testing consisted of bilateral leg extensions at isokinetic velocities of 0.1, 0.3, 0.7, and 1.2 m·s−1. For concurrent validity, 13 ski jumpers (20.3 [3.3] y) were recruited to perform the isokinetic leg-press and SJ P–F–v profile tests using 5 predefined loading conditions of 0%, +20%, +40%, +60%, and +80% of body mass. Results: Relative and absolute reliability were acceptable for female (intraclass correlation coefficient ≥.87 and coefficient of variation ≤6.5%) and male (intraclass correlation coefficient ≥.89 and coefficient of variation ≤5.7%) elite athletes. In contrast, concurrent validity was insufficient, with correlations ranging from −.26 to .69 between isokinetic and SJ P–F–v parameters. Conclusion: Irrespective of sex, isokinetic leg-press P–F–v profiles provide reliable parameters. However, leg-press P–F–v profiles do not serve as a valid substitute for SJ P–F–v profiles. P–F–v parameter magnitudes are likely dependent on the constraints of the tested movement and testing device.
Paediatric inflammatory multisystem syndrome: temporally associated with SARS-CoV-2 (PIMS-TS) — A mimic of intra-abdominal malignancy
Authors: Nasher Omar , Friend Amand , Lakshminarayanan Bhanumathi , Turner Kerry , Wood Mark , Deri Antigoni , Ingham Danielle 
Published: August 2022

We report the case of a school-aged boy who presented with clinical features suggesting acute appendicitis. However, further imaging which included CT, demonstrated an inflammatory mass involving the transverse colon raising the suspicion of lymphoma. He then developed intestinal obstruction, and in view of the rapid progression of the disease, he was thought to have non-Hodgkin’s lymphoma. He underwent an open excisional biopsy, which revealed a necroinflammatory process and no suggestion of lymphoma or an alternative malignancy or specific diagnosis. His steroid treatment was stopped, and he made a good recovery postoperatively. Positive COVID-19 antibodies, positive response to steroids, results and clinical features were consistent with paediatric inflammatory multisystem syndrome (PIMS-TS), with extensive investigation not offering an alternative diagnosis.While PIMS-TS is a relatively new entity, we believe that this case highlights the importance of it being considered a differential diagnosis of a child presenting with an inflammatory mass.
Cost-utility of cytisine for smoking cessation over and above behavioural support in people with newly diagnosed pulmonary tuberculosis: an economic evaluation of a multicentre randomised controlled trial
Authors: Li Jinshuo , Parrott Steve , Keding Ada , Dogar Omara , Gabe Rhian , Marshall Anna-Marie , Huque Rumana , Barua Deepa , Fatima Razia , Khan Amina , Zahid Raana , Mansoor Sonia , Kotz Daniel , Boeckmann Melanie , Elsey Helen , Kralikova Eva , Readshaw Anne , Sheikh Aziz , Siddiqi Kamran 
Published: August 2022

ObjectivesTo assess the cost-effectiveness of cytisine over and above brief behavioural support (BS) for smoking cessation among patients who are newly diagnosed with pulmonary tuberculosis (TB) in low-income and middle-income countries.DesignAn incremental cost-utility analysis was undertaken alongside a 12-month, double-blind, two-arm, individually randomised controlled trial from a public/voluntary healthcare sector perspective with the primary endpoint at 6 months post randomisation.SettingSeventeen subdistrict hospitals in Bangladesh and 15 secondary care hospitals in Pakistan.ParticipantsAdults (aged ≥18 years in Bangladesh and ≥15 years in Pakistan) with pulmonary TB diagnosed within the last 4 weeks who smoked tobacco daily (n=2472).InterventionsTwo brief BS sessions with a trained TB health worker were offered to all participants. Participants in the intervention arm (n=1239) were given cytisine (25-day course) while those in the control arm (n=1233) were given placebo. No significant difference was found between arms in 6-month abstinence.Primary and secondary outcome measuresCosts of cytisine and BS sessions were estimated based on research team records. TB treatment costs were estimated based on TB registry records. Additional smoking cessation and healthcare costs and EQ-5D-5L data were collected at baseline, 6-month and 12-month follow-ups. Costs were presented in purchasing power parity (PPP) adjusted US dollars (US$). Quality-adjusted life years (QALYs) were derived from the EQ-5D-5L. Incremental total costs and incremental QALYs were estimated using regressions adjusting for respective baseline values and other baseline covariates. Uncertainty was assessed using bootstrapping.ResultsMean total costs were PPP US$57.74 (95% CI 49.40 to 83.36) higher in the cytisine arm than in the placebo arm while the mean QALYs were −0.001 (95% CI −0.004 to 0.002) lower over 6 months. The cytisine arm was dominated by the placebo arm.ConclusionsCytisineplusBS for smoking cessation among patients with TB was not cost-effective compared with placeboplusBS.Trial registration numberISRCTN43811467.
Prevalence and associated factors of physical inactivity among middle-aged and older adults in India: results of a national cross-sectional community survey
Authors: Pengpid Supa , Peltzer Karl 
Published: August 2022

ObjectiveThis study aimed to determine the prevalence and associated factors of physical inactivity in middle-aged and older adults in India.DesignPopulation-based cross-sectional study.SettingNationally representative sample of general community-dwelling middle-aged and older adult population in India.ParticipantsThe sample included 72 262 adults (45 years and older, mean age 58.8 years, SD=11.8), from the longitudinal ageing study in India wave 1 in 2017–2018.Primary and secondary outcome measuresSelf-reported physical activity, along with physical measurements, health status and health behaviour, and sociodemographic covariates. Multivariable logistic regression calculated OR with 95% CI for physical inactivity.ResultsOverall, 36.7% were physically inactive, 42.6% among men, and 32.4% among women (p<0.001). In the adjusted logistic regression analysis, among both men and women, older age (70 years and older), being Sikh, impaired vision and depressive symptoms were positively and cognitive functioning, current tobacco use and social participation were negatively associated with physical inactivity. In addition, among men, higher socioeconomic status, urban residence, functional disability and heart disease or stroke were positively associated with physical inactivity, and among women being married and higher education were negatively, and insomnia symptoms and poor or fair self-rated health status were positively associated with physical inactivity.ConclusionsAlmost 4 in 10 middle-aged and older adults in India had inadequate physical activity. Overall and gender specific risk factors for physical inactivity were identified. Interventions may operate at multiple levels and consider gender-related physical inactivity patterns.
Programme of triple-I mediator education (TIME) to improve medical disputes in clinical settings in Taiwan: a Delphi study
Authors: Shiao Yi-Chih , Shen Ruo-Nan , Chen Wen-Wen , Liu Yueh-Ping , Shih Chung-Liang , Wang Chih-Chia 
Published: August 2022

ObjectivesTo establish a training programme to cultivate trainee mediation skills through time investment, skill incorporation and formation of in-house mediation services.DesignA four-round consensus conference was conducted by a number of seasoned experts selected in the manner of purposive sampling to determine core competences and relevant curricula through the modified Delphi process.SettingResponses collected from enrolled experts through four rounds of the Delphi process from 11 November 2018 to 17 May 2019.ParticipantsOnboard seasoned mediators with different specialties.Outcome measuresItems with a median rating of 4 or more on a Likert scale of 1–7 points and 70% or more in agreement were identified as core competence and curricula.ResultsEleven enrolled experts reached the consensus about the training syllabus based on the 4-round agreement with four pillars of core competence, including ‘knowledge base of law’, ‘internalisation of the denotative and connotative meanings of care’, ‘effective, smooth and timely communication’ and ‘conflict resolution’. To grasp the dynamics and diversity of medical disputes on target, it is necessary to have sufficient knowledge and skills. We arrange our course in the order of teaching materials with pure didactics in the former two and with mixed contents comprising lectures and field exercises in the rest two.ConclusionsThe sample developed a syllabus to train apprentices to take intermediate responses to medical disputes through the skills of conflict resolution and establishment of effective communication to improve the relationship between patients/relatives and medical staff, as a result of eventually reducing the conversion rate from dispute into litigation or alternative pathway. Policy-makers in healthcare and top management in healthcare institutions can use this syllabus to guide their future education and training programme.
Examining the criterion validity of two scalable, information technology-based systems designed to measure the quantity and quality of movement behaviours of children from Hong Kong primary schools: a cross-sectional validation study
Authors: Ha Amy S , Cheng James , Chan Cecilia H S , Jiang Guanxian , Yang Yijian , Ng Johan Y Y 
Published: August 2022

ObjectivesResearch has shown that having adequate quantity and quality of physical activity can contribute to the health and well-being of children. Nonetheless, existing tools to measure these constructs in children have limitations in terms of their objectivity and scalability. In this study, we provide criterion validity evidence of two systems built on commercially available sensors (ie, gyroscopes and infrared cameras), designed to measure children’s moderate-to-vigorous physical activity and fundamental movement skill proficiencies.DesignCross-sectional.SettingPrimary schools in Hong Kong.ParticipantsData from 30 (age=8.55±1.25 years) and 1174 (age=9.15±1.63 years) children were included for the validation of physical activity and fundamental movement skills measures, respectively. Children’s outcomes were simultaneously measured using the developed systems and existing, well-established measures (accelerometers and expert ratings).ResultsWe found a strong correlation between physical activity outcomes measured using our developed system and accelerometers (Pearson r=0.795). Motor skill proficiency scored using our real-time rating system had strong agreement with expert ratings (percentage agreement=84%–94%, kappa=0.661 to 0.859).DiscussionResults of the current study supported the application of the respective systems in physical education and large-scale research studies. Collection of such data at mass levels could help researchers depict the complex relation between children’s quantity and quality of physical activity.
Association of occupations with decreased semen quality in eastern China: a cross-sectional study of 12 301 semen donors
Authors: Tang Feng , Jiang Zhaoqiang , Jin Mingying , Sheng Huiqiang , Feng Lingfang , Chen Junfei , Li Yongxin , Huang Jing , Xu Ling , Lou Jianlin 
Published: August 2022

ObjectivesThis study aims to examine the association between occupational factors and semen quality in semen donors in eastern China.MethodsWe recruited 12 301 semen donors from 2006 to 2020 as the studying population. A self-designed questionnaire was applied for collecting lifestyle and work style information. Semen samples were analysed according to WHO guidelines. A crude and adjusted linear regression model was used to analyse the association between occupational factors and semen quality.ResultsCollege students accounted for 36.2% of all semen donors. The majority (81.3%) of semen donors were between 18 year and 30 years. Soldiers or the police had the highest semen volume (the median value=3.8 mL), however, they had the lowest sperm concentration (53.6×106/ml) and sperm motility (45.5%). Workers in finance or insurance had an elevated risk of low semen volume, sperm concentration and total sperm count (OR=1.43, 1.57 and 1.98, respectively). Unemployed men had a high risk of low sperm concentration and low total sperm count (OR=1.84 and 1.58, respectively). Working in the information technology industry had a deleterious effect on the progressive motility of sperm (OR=1.27, 95% CI 1.03 to 1.57).ConclusionOur study indicated that sedentary work style and intensive sports in certain professions might be associated with decreased semen quality. We reported evidence of becoming unemployed on the damage to semen quality. Hence, we advocate a healthy work style to improve semen quality in eastern China.
Adverse pregnancy and birth outcomes associated withMycoplasma hominis, Ureaplasma urealyticumandUreaplasma parvum: a systematic review and meta-analysis
Authors: Jonduo Marinjho Emely , Vallely Lisa Michelle , Wand Handan , Sweeney Emma Louise , Egli-Gany Dianne , Kaldor John , Vallely Andrew John , Low Nicola 
Published: August 2022

ObjectivesMycoplasma hominis, Ureaplasma urealyticumandUreaplasma parvum(genital mycoplasmas) commonly colonise the urogenital tract in pregnant women. This systematic review aims to investigate their role in adverse pregnancy and birth outcomes, alone or in combination with bacterial vaginosis (BV).MethodsWe searched Embase, Medline and CINAHL databases from January 1971 to February 2021. Eligible studies tested for any of the three genital mycoplasmas during pregnancy and reported on the primary outcome, preterm birth (PTB) and/or secondary outcomes low birth weight (LBW), premature rupture of membranes (PROM), spontaneous abortion (SA) and/or perinatal or neonatal death (PND).Two reviewers independently screened titles and abstracts, read potentially eligible full texts and extracted data. Two reviewers independently assessed risks of bias using published checklists. Random effects meta-analysis was used to estimate summary ORs (with 95% CIs and prediction intervals). Multivariable and stratified analyses were synthesised descriptively.ResultsOf 53/1194 included studies, 36 were from high-income countries. In meta-analysis of unadjusted ORs,M. hominiswas associated with PTB (OR 1.87, 95% CI 1.49 to 2.34), PROM, LBW and PND but not SA.U. urealyticumwas associated with PTB (OR 1.96, 95% CI 1.14 to 1.39), PROM, and SA.U. parvumwas associated with PTB (1.79, 95% CI 1.28 to 2.52) and PROM. Seven of 53 studies reported any multivariable analysis. In two studies, analyses stratified by BV status showed thatM. hominisandU. parvumwere more strongly associated with PTB in the presence than in the absence of BV. The most frequent source of bias was a failure to control for confounding.ConclusionsThe currently available literature does not allow conclusions about the role of mycoplasmas in adverse pregnancy and birth outcomes, alone or with coexisting BV. Future studies that consider genital mycoplasmas in the context of the vaginal microbiome are needed.PROSPERO registration numberCRD42016050962.
Impact of COVID-19 pandemic on screening and diagnosis of patients with prostate cancer: a systematic review protocol
Authors: Mostafavi Zadeh Seyed Mostafa , Tajik Fatemeh , Moradi Yousef , Kiani Jafar , Ghods Roya , Madjd Zahra 
Published: August 2022

IntroductionWith the exponential progress of patients with COVID-19, unexpected restrictions were directed to limit SARS-CoV-2 dissemination and imposed health-system an entire reformation to diminish transmission risk. These changes likely have caused the full range of cancer screenings and diagnosis gaps. Regardless of the recommendations, prostate cancer (PCa) screening/diagnosis programmes were momentarily postponed. Prostate-specific antigen (PSA) testing has been an inexpensive, low-invasive and relatively precise means of detection for PCa screening that would improve the uncovering of any type of PCa. Unfortunately, a decrease in PSA screening would significantly decrease PCa detection, with non-negligible growth in PCa-specific death. This review is designed to improve our understanding of the impact of the COVID-19 pandemic on the screening and diagnosis of patients with PCa.Methods and analysisThis systematic review will be reported in accordant with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidance. A comprehensive search has been executed through five main electronic databases: PubMed/MEDLINE, Web of Science, Scopus, Embase and ProQuest until 1 March 2022. Besides, grey literature, preprint studies and references of included studies will be searched. The main keywords have been used to perform the search strategy: COVID-19, prostatic neoplasms. All the relevant studies that met the inclusion criteria will be screened, selected and then extracted data by two independent authors. The quality assessment of the included studies will be performed by the Newcastle-Ottawa Scale. In case of any disagreement between the two authors in selecting, extracting data and assessing the quality of included studies, it will be resolved via consensus and checked by the third author.Ethics and disseminationAs this study will be a systematic review without human participants’ involvement, there will be no requirement for ethics approval. Findings will be presented at conferences and in a peer-reviewed journal.PROSPERO registration numberCRD42021291656.
Risk of stroke in multiple sclerosis and neuromyelitis optic spectrum disorder: a Nationwide cohort study in South Korea
Authors: Cho Eun Bin , Yeo Yohwan , Jung Jin Hyung , Jeong Su-Min , Han Kyung-do , Shin Dong Wook , Min Ju-Hong 
Published: August 2022

BackgroundPeople with multiple sclerosis (MS) are more likely to develop stroke than those without. However, little is known about the association between neuromyelitis optica spectrum disorder (NMOSD) and the risk of stroke. We aimed to estimate the risk of stroke in patients with MS and NMOSD in South Korea.MethodsData from the Korean National Health Insurance between January 2010 and December 2017 were analysed. A total of 1541/1687 adult patients with MS/NMOSD, who were free of stroke were included. Matched controls were selected based on age, sex and the presence of hypertension, diabetes mellitus and dyslipidaemia.ResultsThe risk of developing stroke was 2.78 times higher (adjusted HR (aHR), 95% CI 1.91 to 4.05) in patients with MS compared with controls matched by age, sex, hypertension, diabetes mellitus and dyslipidaemia. The risk of stroke in NMOSD was also higher than that in matched controls (aHR=1.69, 95% CI 1.10 to 2.61) and not statistically different from that of MS (p=0.216). The patients with MS had a higher risk for either of ischaemic or haemorrhagic stroke (HR=2.63 and 2.93, respectively), whereas those with NMOSD had a higher risk for ischaemic stroke (HR=1.60) with marginal statistical significance.ConclusionsThe risk of stroke is increased in patients with MS and NMOSD and seemed comparable between the two conditions. This is the first study that estimates the risk of stroke in patients with MS and NMOSD within the same population.
Crosstalk among apoptosis, inflammation, and autophagy in relation to melatonin protective effect against contrast-induced nephropathy in rats
Authors: Al-Shawadfy Marwa Gamal , Kamel Gellan Alaa Mohamed , Abd-Allah Adel R.A. 
Published: August 2022

Contrast medium (CM) is a chemical substance that is used for imaging anatomical boundaries and to explore normal and abnormal physiological findings; the use of CM was associated with kidney injury and acute renal failure. Melatonin (M) possesses antioxidant, anti-inflammatory, and antiapoptotic effects in addition to autophagy modulation. This study aimed to investigate the protective effect of M against contrast-induced nephropathy (CIN) and its impact on the crosstalk between inflammasome, apoptosis, and autophagy in CIN. Male albino rats received M (10, 20, and 40 mg/kg/day, intraperitoneally) for 3 days. One hour after the last administration, rats were subjected to CIN induction (10 mg/kg indomethacin, double doses of l-NAME 10 mg/kg, i.v., and meglumine diatrizoate 60% 6 mL/kg, i.v.). CIN-induced kidney damage was evidenced through elevated kidney function biomarkers and induced renal histopathological changes. Pretreatment with M caused a significant decrease in nephrotoxicity biomarkers and histopathological alterations. Moreover, CIN-induced oxidative stress, NLRP3 inflammasome, and apoptosis were attenuated by M. Furthermore, M modulates autophagy in CIN rats. M inhibits CIN-induced NLRP3-inflammasome activation and apoptosis as well as enhances autophagy.
First report of the mymarid genus Proarescon Huber (Hymenoptera: Chalcidoidea: Mymaridae) from India
Authors: Ayyavu Athithya  , Sagadai Manickavasagam  
Published: August 2022

Fairyfly genus Proarescon Huber, 2017 (Hymenoptera: Mymaridae) is reported for the first time from India and the specific identity is confirmed as P. primitivus (Huber, 2002) after consulting keys from Huber (2017); this genus is still known only from the Oriental region. A note on diagnosis and distribution of this species is also provided.
Sam & Bram
Authors: Houppermans Sjef 
Published: August 2022

Résumé
Entre Sam et Bram les lignes sont complexes et les couleurs varient. Amis et compagnons, sur des chemins de traverse, ils se rencontrent dans leur conception absolue de l’œuvre d’art. Beckett tente de parler des peintures et y reconnaît (là aussi) un inévitable échec. Bram lit Sam et aime s’y perdre.
« Vu autrement »
Authors: Genetti Stefano 
Published: August 2022

Résumé
La mise en scène de Cap au pire conçue en 2006 par la chorégraphe Maguy Marin et interprétée par Françoise Leick plonge dans la pénombre la lecture intégrale en voix off du texte beckettien. L’installation de Peter Welz whenever on on on nohow on|airdrawing (2004) multiplie les captations de la performance que William Forsythe improvise à partir d’une phrase inspirée de Worstward Ho. En illustrant les apparitions et les disparitions des images et en inscrivant dans l’espace des traces de mots à la croisée de danse, vidéo-sculpture, dessin et architecture, ces deux œuvres visualisent et interrogent les tensions entre perception et imagination, présence et absence, voir et dire.
De La Cerisaie à En attendant Godot
Authors: Mével Yann 
Published: August 2022

Résumé
Une mise en scène de La Cerisaie présentée en 2021 par Tiago Rodrigues dans le cadre du festival d’Avignon permettait de prendre conscience des liens étroits qu’entretient cette pièce avec En attendant Godot. Notre analyse des convergences prend d’abord pour objets les rapports entre tragique et comique – ce dernier l’emportant selon Tchekhov –, ce qu’il reste d’action(s) et de psychologie. La représentation de l’espace et du temps, dans ces pièces, échappe au symbolisme. Le langage y exprime la difficulté d’éviter le monologue, malgré le besoin de rester en relation avec autrui. La comparaison de plusieurs scènes met en lumière de remarquables analogies entre ces pièces.