bluuebunny/crossref_metadata_2025_split huggingface dataset:
Local Community Policy and The Value of Local Wisdom of The Kemang Plant
Authors: Solihin S , Fitriyah A , Muliyah Evi 
Published: December 2022

Abstract
Kemang plant is a plant that has the value of local wisdom in certain areas, especially in Bogor and Sukabumi. This study aims to determine the values of environmental policy and the value of local wisdom which is the basis for mysticism in specific communities toward the Kemang plant. The method used is qualitative with a descriptive analysis research design. The research sample consisted of 46 people who were taken by random sampling technique. The variables studied are indicators of plant availability, utilization of plants, aspects of local knowledge, local social processes, and circulating local wisdom values. The local community uses the plant as food and board, based on field results that the Kemang plant is experiencing extinction. 95% of the community believes that Buyut nonactive disease if passes the Kemang plant, its Buyut is nonactive will experience active disease. 89% of people with Buyut disease have the condition.
Extraction of rice bran oil using microwave-assisted extraction and green solvents
Authors: Gotama B , Rahman A K , Ahmad A , Hariyadi A 
Published: December 2022

Abstract
Rice bran oil (RBO) is a healthy vegetable oil made from rice bran. A microwave- assisted extraction method (MAE) was developed in this work to produce RBO with greater productivity than the conventional method, i.e., solvent extraction (SXE). Furthermore, green solvents such as ethanol and d-limonene were compared as an alternative to the less environmentally friendly n-hexane. An evaluation of energy consumption and raw material costs was conducted using the MAE method. The 30 mesh bran was stabilized in the oven for 30 min at 100°C followed by MAE extraction, which was performed by mixing 50 g of bran and 300 ml of solvents in a microwave oven set to 450 watts and 60°C for 60 min. Filter paper was used to separate the extract from the bran, and the oil was recovered by solvent evaporation. Finally, the oil was weighed and the fatty acid composition was determined by GC-MS. The results showed that the yield of RBO using d-limonene and MAE was the largest (24.64%) as well as consuming less energy (95Wh/gr oil). Linoleic acid was only found in the extraction with d-limonene and EtOH was successful in obtaining longer-chain saturated fatty acids.
Micro-scale deterministic asperity contact FEM simulation
Authors: Kolli Vasu , Winkler Andreas , Wartzack Sandro , Marian Max 
Published: December 2022

Abstract
There are numerous stochastic approaches to indirectly couple solid asperity contact with the fluid hydrodynamics in the region of boundary or mixed lubrication. In contrast, deterministic approaches for calculating solid contact pressure curves offer advantages in terms of flexibility and accuracy. This contribution aims at providing a publicly available, automated method to derive solid asperity contact pressure curves for given surfaces, implemented in commercial software based upon Finite Element Method (FEM). Solid asperity pressure curves were calculated and compared to various established stochastic models for artificially generated surfaces and surfaces measured via laser scanning microscopy. Thereby, it was shown that the usage of artificially generated surfaces based on stochastic parameters only allowed an approximate representation of real measured surfaces as well as to lower calculated pressures, so that 3D measurement data is preferred to calculate the contact pressure. Moreover, the values of the FEM model were in a similar region but slightly below the stochastic models over a wide range of gap distances and the asperity pressure graphs were more curved/convex. At very small gap height values, the pressure in the FEM model reached values similar to the stochastic models. This was attributed to the fact that real surface topographies were considered, also allowing for peak-to-valley pairings instead of merely asperity-to-asperity contacts, as well as to the fact that the roughness and mean planes were re-calculated in each simulation step, while most stochastic approaches neglect the elastic deformation of asperities when determining the distances between the rough surfaces.
Influence of Na2WO4 additive in electrolyte on properties of plasma electrolytic oxidation coatings on H62 brass
Authors: Guan Qingyi , Meng Jianbing , Wang Shuaike , Dong Xiaojuan , Zhou Haian , Yu Haoyang , Li Hongmei 
Published: December 2022

Abstract
In order to improve the corrosion resistance of brass treated by plasma electrolytic oxidation (PEO), Na2WO4 additive was introduced into a mixed electrolyte of sodium silicate and sodium hydroxide, and a composite oxide coating was formed on the surface of H62 brass. The effect of Na2WO4 concentration from 0 to 3 g L−1 in silicate-based electrolyte on the properties of PEO coatings was investigated by SEM, EDS, XRD and electrochemical workstation. The results show that the element of W in the form of metal oxides can be successfully incorporated into PEO coatings. The addition of Na2WO4 can significantly improve the corrosion resistance of PEO coatings, and the best corrosion resistance is obtained when the addition amount is 1.0 g L−1.
Atomistic study on the nano-scratch mechanism of CoCrFeMnNi high-entropy alloy at different morphology densities
Authors: Wang Bing , Luo Rong , Wang Qian , Liu Haidong 
Published: December 2022

Abstract
The physical nature of the scratch behavior of CoCrFeMnNi HEA and its deformation mechanism at different morphology densities are investigated by molecular dynamics simulations. The results show that the groove morphology contributes to the reduction of surface plastic deformation and exhibits a friction-reducing effect. As the morphology density decreases, the surface deformation and atom pile-up decrease, and the plastic deformation in the scratch region decreases, resulting in a further enhancement of the friction reduction effect. The increase of scratch depth intensifies the plastic deformation of the specimens, and the average scratch coefficient of friction increases with the increase in scratch depth. The dominant plastic deformation mechanism in the scratch deformation of CoCrFeMnNi HEA with different morphology densities is the slip deformation of Shockley partial dislocations. The MD simulations are verified further by qualitatively comparing them with corresponding experimental observations of CoCrFeMnNi HEA.
Determination of the dielectric constant of non-planar nanostructures and single nanoparticles by electrostatic force microscopy
Authors: Fuhrmann Marc , Musyanovych Anna , Thoelen Ronald , Moebius Hildegard 
Published: December 2022

Abstract
Electrostatic Force Microscopy has been proven to be a precise and versatile tool to perform quantitative measurements of the dielectric constant of thin film domains in the nanometer range. However, it is difficult to measure non-planar nanostructures because topographic crosstalk significantly contributes to the measured signal. This topographic crosstalk due to distance changes between tip and substrate measuring non-planar surface structures is still an ongoing issue in literature and falsifies measurements of the dielectric constant of nanostructures and nanoparticles. Tip and substrate form a capacitor based on the contact potential difference between the tip and substrate material. An increase of the distance between tip and substrate causes a repulsive force while a decrease causes an attractive force. Thus, measuring in the so-called lift mode scanning the surface in a second scan following the topography determined by a first scan leads to a mirroring of the non-planar surface structure in the electrostatic signal superimposing the signal from dielectric contrast. In this work we demonstrate that the topographic crosstalk can be avoided by using the linear mode instead of the lift mode. The use of the linear mode now allows the determination of the dielectric constant of single nanoparticles.
Hydrogen storage in liquid hydrogen carriers: recent activities and new trends
Authors: Ulucan Tolga Han , Akhade Sneha A , Ambalakatte Ajith , Autrey Tom , Cairns Alasdair , Chen Ping , Cho Young Whan , Gallucci Fausto , Gao Wenbo , Grinderslev Jakob B , Grubel Katarzyna , Jensen Torben R , de Jongh Petra E , Kothandaraman Jotheeswari , Lamb Krystina E , Lee Young-Su , Makhloufi Camel , Ngene Peter , Olivier Pierre , Webb Colin J , Wegman Berenger , Wood Brandon C , Weidenthaler Claudia 
Published: December 2022

Abstract
Efficient storage of hydrogen is one of the biggest challenges towards a potential hydrogen economy. Hydrogen storage in liquid carriers is an attractive alternative to compression or liquefaction at low temperatures. Liquid carriers can be stored cost-effectively and transportation and distribution can be integrated into existing infrastructures. The development of efficient liquid carriers is part of the work of the International Energy Agency Task 40: Hydrogen-Based Energy Storage. Here, we report the state-of-the-art for ammonia and closed CO2-cycle methanol-based storage options as well for liquid organic hydrogen carriers.
Active upper limb prostheses: a review on current state and upcoming breakthroughs
Authors: Marinelli Andrea , Boccardo Nicolò , Tessari Federico , Di Domenico Dario , Caserta Giulia , Canepa Michele , Gini Giuseppina , Barresi Giacinto , Laffranchi Matteo , De Michieli Lorenzo , Semprini Marianna 
Published: December 2022

AbstractThe journey of a prosthetic user is characterized by the opportunities and the limitations of a device that should enable activities of daily living (ADL). In particular, experiencing a bionic hand as a functional (and, advantageously, embodied) limb constitutes the premise for promoting the practice in using the device, mitigating the risk of its abandonment. In order to achieve such a result, different aspects need to be considered for making the artificial limb an effective solution to accomplish ADL. According to such a perspective, this review aims at presenting the current issues and at envisioning the upcoming breakthroughs in upper limb prosthetic devices. We first define the sources of input and feedback involved in the system control (at user-level and device-level), alongside the related algorithms used in signal analysis. Moreover, the paper focuses on the user-centered design challenges and strategies that guide the implementation of novel solutions in this area in terms of technology acceptance, embodiment, and, in general, human-machine integration based on co-adaptive processes. We here provide the readers (belonging to the target communities of researchers, designers, developers, clinicians, industrial stakeholders, and end-users) with an overview of the state-of-the-art and the potential innovations in bionic hands features, hopefully promoting interdisciplinary efforts for solving current issues of upper limb prostheses. The integration of different perspectives should be the premise to a transdisciplinary intertwining leading to a truly holistic comprehension and improvement of the bionic hands design. Overall, this paper aims to move the boundaries in prosthetic innovation beyond the development of a tool and toward the engineering of human-centered artificial limbs.
Optimizing simple calreticulin upregulation strategies in Caenorhabditis elegans
Authors: Guijarro-Hernández Ana , Hurtado Cristina , Vizmanos José Luis 
Published: December 2022

Abstract
Calreticulin (CALR) is a multifunctional calcium-binding protein whose expression levels have been correlated with detection, clinical phase of disease, metastasis, and survival of various types of cancer. Therefore, the study of the regulation of the cellular levels of CALR may be important to understand the neoplastic process. Caenorhabditis elegans, which has a CALR ortholog (CRT-1), has been used as a model organism for the characterization of CALR, and several conditions promoting the upregulation of crt-1 have been studied and established to understand the molecular control of crt-1 transcription and assess the function of the protein. Here, we propose several modifications of previously published crt-1 upregulation strategies that improve the reproducibility of the assay and allow to achieve higher levels of overexpression. First, the manipulation of synchronized populations of worms instead of mixed-stage animals and the use of solid culture medium in all experimental conditions are proposed. Likewise, we evaluate four new experimental approaches that attempt to promote a higher crt-1 upregulation [short-term exposure to 30 µg/ml tunicamycin at 25°C, short-term exposure to 7% ethanol (EtOH) at 25°C, short-term exposure to 30°C of worms grown at 25°C, and a long-term exposure to 7% EtOH]. Our results not only validate previously published methods, but also point to a new experimental approach that increases previously achieved levels of crt-1 upregulation. More specifically, a 6-h exposure of synchronized worms grown at 25°C to 7% EtOH on solid medium promotes almost a 7-fold upregulation of crt-1.
Impact of baseline blood pressure on adverse outcomes in Japanese patients with non-valvular atrial fibrillation: the J-RISK AF
Authors: Kodani Eitaro , Tomita Hirofumi , Nakai Michikazu , Akao Masaharu , Suzuki Shinya , Hayashi Kenshi , Sawano Mitsuaki , Goya Masahiko , Yamashita Takeshi , Fukuda Keiichi , Ogawa Hisashi , Tsuda Toyonobu , Isobe Mitsuaki , Toyoda Kazunori , Miyamoto Yoshihiro , Miyata Hiroaki , Okamura Tomonori , Sasahara Yusuke , Okumura Ken ,   for the J-RISK AF Research Group
Published: December 2022

Abstract

Aims
This study aimed to investigate the impact of baseline blood pressure (BP) on adverse outcomes in patients with atrial fibrillation (AF), using a pooled analysis performed on data from J-RISK AF, a large-scale cohort of Japanese patients with AF.

Methods and results
Of the 16 918 patients from five major AF registries including the J-RHYTHM Registry, Fushimi AF Registry, Shinken Database, Keio interhospital Cardiovascular Studies, and Hokuriku-Plus AF Registry, 15 019 non-valvular AF (NVAF) patients with baseline BP values (age, 70.0 ± 11.0 years; men, 69.1%) were analysed. Incidence rates of adverse events were evaluated between patients divided into baseline systolic BP quartiles or at 150 mmHg. During the follow-up period of 730 days, ischaemic stroke, major bleeding, all-cause death, and cardiovascular death occurred in 277, 319, 718, and 275 patients, respectively. Hazard ratios (HRs) for ischaemic stroke and major bleeding were comparable among the quartiles, whereas HRs for all-cause and cardiovascular deaths in the lowest quartile with systolic BP &lt;114 mmHg were significantly higher [HR 1.43, 95% confidence interval (CI) 1.13–1.81; and HR 1.47, 95% CI 1.01–2.12, respectively] than in the third quartile, even after adjusting for known confounding factors. In patients with a systolic BP of ≥150 mmHg, adjusted HR for major bleeding was significantly higher than that of &lt;150 mmHg (HR 1.64, 95% CI 1.12–2.40).

Conclusion
In Japanese patients with NVAF, a baseline systolic BP &lt;114 mmHg was significantly associated with higher all-cause and cardiovascular mortality. In contrast, a systolic BP ≥150 mmHg was an independent risk factor for major bleeding.
A rationale for dedicated trials of combination therapy in heart failure
Authors: Blumer Vanessa , Vaduganathan Muthiah 
Published: December 2022

Abstract
As heart failure (HF) enters a new era with high level of evidence supporting the use of individual drug therapies, we put forth a rationale for the need for dedicated investigation of the safety, tolerability, and practicalities associated with combination medical therapy. Being able to tailor therapies via combination approaches might offer a way to maximize benefits of available therapies and also facilitate compliance. The evidentiary bar to support multi-drug regimens should be raised in HF for a variety of reasons: (1) Pivotal HF randomized controlled trials (RCTs) to date have not traditionally tested and proven safety and efficacy of drug combinations, (2) HF patients have variable disease trajectories, (3) There is hesitancy by clinicians and patients to using multiple drugs and such trials may build confidence in their use, and (4) HF therapies have overlapping side effects. Similar to combination therapies being developed and tested in adjacent fields of medicine, HF care too would greatly benefit from dedicated investigations of combination treatment approaches. Personalizing precision medicine with combination therapies has the potential to further improve outcomes and facilitate optimal implementation of disease-modifying therapies in HF.
Population genomics and subgenome evolution of the allotetraploid frog Xenopus laevis in southern Africa
Authors: Premachandra Tharindu , Cauret Caroline M S , Conradie Werner , Measey John , Evans Ben J 
Published: December 2022

Abstract
Allotetraploid genomes have two distinct genomic components called subgenomes that are derived from separate diploid ancestral species. Many genomic characteristics such as gene function, expression, recombination, and transposable element mobility may differ significantly between subgenomes. To explore the possibility that subgenome population structure and gene flow may differ as well, we examined genetic variation in an allotetraploid frog—the African clawed frog (Xenopus laevis)—over the dynamic and varied habitat of its native range in southern Africa. Using reduced representation genome sequences from 91 samples from 12 localities, we found no strong evidence that population structure and gene flow differed substantially by subgenome. We then compared patterns of population structure in the nuclear genome to the mitochondrial genome using Sanger sequences from 455 samples from 183 localities. Our results provide further resolution to the geographic distribution of mitochondrial and nuclear diversity in this species and illustrate that population structure in both genomes corresponds roughly with variation in seasonal rainfall and with the topography of southern Africa.
Two-locus identity coefficients in pedigrees
Authors: Vigeland Magnus Dehli 
Published: December 2022

Abstract
This paper proposes a solution to a long-standing problem concerning the joint distribution of allelic identity by descent between two individuals at two linked loci. Such distributions have important applications across various fields of genetics, and detailed formulas for selected relationships appear scattered throughout the literature. However, these results were obtained essentially by brute force, with no efficient method available for general pedigrees. The recursive algorithm described in this paper, and its implementation in R, allow efficient calculation of two-locus identity coefficients in any pedigree. As a result, many existing procedures and techniques may, for the first time, be applied to complex and inbred relationships. Two such applications are discussed, concerning the expected likelihood ratio in forensic kinship testing, and variances in realized relatedness.
Dynamic simulations of coseismic slickenlines on non-planar and rough faults
Authors: Aoki T , Kaneko Y , Kearse J 
Published: December 2022

SUMMARY
Knowing the directions of rupture propagation of palaeo-earthquakes is a challenging, yet important task for our understanding of earthquake physics and seismic hazard, as the rupture direction significantly influences the distribution of strong ground motion. Recent studies proposed a relationship between the direction of rupture propagation and curvature of slickenlines formed during seismic slip. The relationship was established using a global catalogue of historic surface-rupturing earthquakes and dynamic models of idealized, planar faults. At the same time, some slickenlines previously documented on geometrically complex fault segments show their convexity opposite from the simple model prediction, which we refer to as ‘abnormal convexity’. To explain such observations, we perform simulations of spontaneous earthquake ruptures on non-planar and rough faults. We find that in the case of strike-slip faults, a non-planar fault model can lead to abnormal convexity of slickenlines in places where the fault dip angle changes abruptly from the average dip of the fault. Abnormal convexity of slickenlines is produced when the initial along-dip stresses are larger than, and are opposite in direction to, the dynamic stresses imparted by the mixed-mode rupture. Such results are also confirmed in our rupture simulations with a rough fault. Our results also show that the parameter space for which abnormal convexity of slickenlines occurs near Earth’s surface is narrow, especially when the fault strength and initial shear stresses increase with depth. Nevertheless, slickenlines on geometrically complex faults need to be carefully interpreted and investigation of rupture direction using curved slickenlines should focus on structurally simple parts of faults.
Field Overlaps, Normativity, and the Contestation of Practices in China's Belt and Road Initiative
Authors: Lesch Max , Loh Dylan M H 
Published: December 2022

Abstract
China's Belt and Road Initiative (BRI) is a cornerstone of Xi Jinping's foreign policy. Chinese ministries, companies, and universities set up diplomatic networks, build roads and harbors, and facilitate scientific projects and educational programs to implement the BRI. Whereas some see the BRI as an integration project, others contend that it challenges the existing international order. We introduce the concept of field overlaps to study the normativity of international practices and argue that state and non-state actors contest international practices by drawing on competing normative inventories anchored in overlapping fields. We illustrate this argument by zooming in on China's infrastructural and educational practices. Their normativity comes to the fore in their ongoing contestation as they travel diplomatic, economic, security, and educational fields. Focusing on field overlaps provides a promising avenue for studying how actors stabilize, modify, or disrupt the normativity of international practices.
Culturally Competent Care in the Breast Imaging Clinic: Hispanic/Latino Patients
Authors: Feliciano-Rivera Yara Z , Net Jose , Sanchez Priscila , Wahab Rifat A , Mehta Tejas , Yepes Monica M 
Published: December 2022

AbstractHispanic/Latino people represent 19% of the U.S. population, and this proportion is expected to increase to 26% by 2050. Hispanic/Latino people comprise a diverse ethnic group that includes individuals from all races, religions, languages, cultural identities, and nationalities. Barriers to health care that have created significant disparities in this community include language, low socioeconomic status, and inability to afford health insurance. Health coverage for Hispanic/Latino people has been a longstanding problem in the U.S., stopping many of these patients from seeking preventive care such as screening mammography. Breast cancer is the most common cancer among Hispanic/Latino women in the U.S. and the leading cause of cancer death in this group. Five-year breast cancer survival in Hispanic/Latino women is slightly lower than that in non-Hispanic White women. Some of the factors that account for the ethnic disparities in breast cancer include lower levels of adherence to screening mammography of Hispanic/Latino women as a consequence of inadequate insurance coverage, language barriers, lack of transportation, being unable to leave work, and lack of childcare. By promoting a culturally sensitive clinical environment, breast radiologists can increase patient engagement, utilization of preventive services, treatment adherence rates, and overall health status.