bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnesium and barium in two substructures: BaTMg2 (T = Pd, Ag, Pt, Au) and the isotypic cadmium compound BaAuCd2 with MgCuAl2 type structure
Authors: Reimann Maximilian Kai , Pöttgen Rainer 
Published: November 2022

Abstract
The intermetallic barium compounds BaTMg2 (T = Pd, Ag, Pt, Au) and BaAuCd2 were synthesized by reactions of the elements in sealed tantalum ampoules in muffle furnaces. The five compounds crystallize with the orthorhombic MgCuAl2 type structure, space group Cmcm, with small differences in chemical bonding between the magnesium and cadmium series. All samples were characterized through their Guinier powder diffraction patterns. The structures of BaPdMg2 (a = 444.57(4), b = 1174.67(10), c = 827.58(7) pm, wR2 = 0.0460, 475 F
2 values, 16 variables), BaAuMg2 (a = 450.27(6), b = 1183.94(16), c = 838.76(11) pm, wR2 = 0.0355, 473 F
2 values, 16 variables) and BaAuCd2 (a = 463.31(5), b = 1112.79(12), c = 826.63(8) pm, wR2 = 0.0453, 469 F
2 values, 16 variables) were refined from single crystal X-ray diffraction data. The large barium atoms push the [TMg2] respectively [AuCd2] substructures apart. This allows fast moisture attack and leads to fast hydrolyzes of the samples when they get in contact with water. The influence of the difference in electronegativity between magnesium and cadmium is reflected for the pair of compounds BaAuMg2 and BaAuCd2. The magnesium compound shows the higher auridic character, while the cadmium compound shows a tendency towards a three-dimensional cadmium substructure.
Hybride Organisationsformen in der Produktion
Authors: Bleckmann Marco , Schumann Dorit , Mütze Alexander , Oubari Assem , Nyhuis Peter 
Published: November 2022

Abstract
Der Zielgrößenkonflikt zwischen Produktivität und der Beherrschbarkeit eines wachsenden Produktspektrums stellt die Montagesysteme zahlreicher industrieller Unternehmen vor große Herausforderungen. Die Fähigkeiten bestehender Organisationsformen reichen nicht mehr aus, um variantenzeitdivergierende Inhalte in einem wirtschaftlichen Zusammenhang abbilden zu können. Im Rahmen des Forschungsprojekts HyFlowJobShop werden alternative hybride Organisationsformen konzipiert und produktionslogistische Simulationen für Fließ-Werkstatt-Kombinationen zu deren Bewertung durchgeführt.
Cortical Pyramidal and Parvalbumin Cells Exhibit Distinct Spatiotemporal Extracellular Electric Potentials
Authors: Sukman Lior J. , Stark Eran 
Published: November 2022

AbstractBrain circuits are composed of diverse cell types with distinct morphologies, connections, and distributions of ion channels. Modeling suggests that the spatial distribution of the extracellular voltage during a spike depends on cellular morphology, connectivity, and identity. However, experimental evidence from the intact brain is lacking. Here, we combined high-density recordings from hippocampal region CA1 and neocortex of freely moving mice with optogenetic tagging of parvalbumin-immunoreactive (PV) cells. We used ground truth tagging of the recorded pyramidal cells (PYR) and PV cells to construct binary classification models. Features derived from single-channel waveforms or from spike timing alone allowed near-perfect classification of PYR and PV cells. To determine whether there is unique information in the spatial distribution of the extracellular potentials, we removed all single-channel waveform information from the multichannel waveforms using an event-based delta-transformation. We found that spatiotemporal features derived from the transformed waveforms yield accurate classification. The extracellular analog of the spatial distribution of the initial depolarization phase provided the highest contribution to the spatially based prediction. Compared with PV cell spikes, PYR spikes exhibited higher spatial synchrony at the beginning of the extracellular spike and lower synchrony at the trough. The successful classification of PYR and PV cells based on purely spatial features provides direct experimental evidence that spikes of distinct cell types are associated with distinct spatial distributions of extracellular potentials.
Intracellular Accumulation of α-Synuclein Aggregates Promotes S-Nitrosylation of MAP1A Leading to Decreased NMDAR-Evoked Calcium Influx and Loss of Mature Synaptic Spines
Authors: Hallam Ryan D. , Buchner-Duby Brodie , Stykel Morgan G. , Coackley Carla L. , Ryan Scott D. 
Published: November 2022

Cortical synucleinopathies, including dementia with Lewy bodies and Parkinson's disease dementia, collectively known as Lewy body dementia, are characterized by the aberrant aggregation of misfolded α-synuclein (α-syn) protein into large inclusions in cortical tissue, leading to impairments in proteostasis and synaptic connectivity and eventually resulting in neurodegeneration. Here, we show that male and female rat cortical neurons exposed to exogenous α-syn preformed fibrils accumulate large, detergent-insoluble, PS129-labeled deposits at synaptic terminals. Live-cell imaging of calcium dynamics coupled with assessment of network activity reveals that aberrant intracellular accumulation of α-syn inhibits synaptic response to glutamate through NMDARs, although deficits manifest slowly over a 7 d period. Impairments in NMDAR activity temporally correlated with increased nitric oxide synthesis and S-nitrosylation of the dendritic scaffold protein, microtubule-associated protein 1A. Inhibition of nitric oxide synthesis via the nitric oxide synthase inhibitorl-NG-nitroarginine methyl ester blocked microtubule-associated protein 1A S-nitrosylation and normalized NMDAR-dependent inward calcium transients and overall network activity. Collectively, these data suggest that loss of synaptic function in Lewy body dementia may result from synucleinopathy-evoked nitrosative stress and subsequent NMDAR dysfunction.SIGNIFICANCE STATEMENTThis work shows the importance of the redox state of microtubule-associated protein 1A in the maintenance of synaptic function through regulation of NMDAR. We show that α-syn preformed fibrils promote nitric oxide synthesis, which triggers S-nitrosylation of microtubule-associated protein 1A, leading to impairment of NMDAR-dependent glutamate responses. This offers insight into the mechanism of synaptic dysfunction in Lewy body dementia.
m6A methyltransferase METTL3 inhibits endometriosis by regulating alternative splicing of MIR17HG
Authors: Li Qian , Yang Li , Zhang Feng , Liu Jiaxi , Jiang Min , Chen Yannan , Ren Chenchen 
Published: November 2022

In brief
Inflammation and abnormal immune response are the key processes in the development of endometriosis (EMs), and m6A modification can regulate the inflammatory response. This study reveals that METTL3-mediated N6-methyladenosine (m6A) modification plays an important role in EMs.

Abstract
m6A modification is largely involved in the development of different diseases. This study intended to investigate the implication of m6A methylation transferase methyltransferase like 3 (METTL3) in EMs. EMs- and m6A-related mRNAs and long non-coding RNAs were identified through bioinformatics analysis. Next, EM mouse models established by endometrial autotransplantation and mouse endometrial stromal cell (mESC) were prepared and treated with oe-METTL3 or sh-MIR17HG for pinpointing the in vitro and in vivo effects of METTL3 on EMs in relation to MIR17HG through the determination of mESC biological processes as well as estradiol (E2) and related lipoprotein levels. We demonstrated that METTL3 and MIR17HG were downregulated in the EMs mouse model. Overexpression of METTL3 suppressed the proliferation, migration, and invasion of mESCs. In addition, METTL3 enhanced the expression of MIR17HG through m6A modification. Moreover, METTL3 could inhibit the E2 level and alter related lipoprotein levels in EMs mice through the upregulation of MIR17HG. The present study highlighted that the m6A methylation transferase METTL3 prevents EMs progression by upregulating MIR17HG expression.
Chronic Iron Deficiency and Cognitive Function in Early Childhood
Authors: Gingoyon Argie , Borkhoff Cornelia M. , Koroshegyi Christine , Mamak Eva , Birken Catherine S. , Maguire Jonathon L. , Fehlings Darcy , Macarthur Colin , Parkin Patricia C. 
Published: November 2022

BACKGROUND AND OBJECTIVES
A landmark longitudinal study, conducted in Costa Rica in the 1980s, found that children with chronic iron deficiency compared with good iron status in infancy had 8 to 9 points lower cognitive scores, up to 19 years of age. Our objective was to examine this association in a contemporary, high-resource setting.

METHODS
This was a prospective observational study of children aged 12 to 40 months screened with hemoglobin and serum ferritin. All parents received diet advice; children received oral iron according to iron status. After 4 months, children were grouped as: chronic iron deficiency (iron deficiency anemia at baseline or persistent nonanemic iron deficiency) or iron sufficiency (IS) (IS at baseline or resolved nonanemic iron deficiency). Outcomes measured at 4 and 12 months included the Early Learning Composite (from the Mullen Scales of Early Learning) and serum ferritin.

RESULTS
Of 1478 children screened, 116 were included (41 chronic, 75 sufficient). Using multivariable analyses, the mean between-group differences in the Early Learning Composite at 4 months was −6.4 points (95% confidence interval [CI]: −12.4 to −0.3, P = .04) and at 12 months was −7.4 points (95% CI: −14.0 to −0.8, P = .03). The mean between-group differences in serum ferritin at 4 months was 14.3 μg/L (95% CI: 1.3–27.4, P = .03) and was not significantly different at 12 months.

CONCLUSIONS
Children with chronic iron deficiency, compared with children with IS, demonstrated improved iron status, but cognitive scores 6 to 7 points lower 4 and 12 months after intervention. Future research may examine outcomes of a screening strategy on the basis of early detection of iron deficiency using serum ferritin.
Winograd schemata and other datasets for anaphora resolution in Hungarian
Authors: Vadász Noémi , Ligeti-Nagy Noémi 
Published: November 2022

AbstractThe Winograd Schema Challenge (WSC, proposed by Levesque, Davis & Morgenstern 2012) is considered to be the novel Turing Test to examine machine intelligence. Winograd schema questions require the resolution of anaphora with the help of world knowledge and commonsense reasoning. Anaphora resolution is itself an important and difficult issue in natural language processing, therefore, many other datasets have been created to address this issue. In this paper we look into the Winograd schemata and other Winograd-like datasets and the translations of the schemata to other languages, such as Chinese, French and Portuguese. We present the Hungarian translation of the original Winograd schemata and a parallel corpus of all the translations of the schemata currently available. We also adapted some other anaphora resolution datasets to Hungarian. We aim to discuss the challenges we faced during the translation/adaption process.
Predictions of the 1997 strong earthquakes in Jiashi, Xinjiang, China
Authors: Zhang Guomin , Zhu Lingren , Song Xiaodong , Li Zhixiong , Yang Maling , Su Naiqin , Chen Xuezhong 
Published: November 2022

Abstract
A sequence of strong earthquakes occurred in Jiashi County, Xinjiang, China (40°N, 77°E, population 280,000) in 1997, after a 10-month quiescence following a Ms 6.9 earthquake on 19 March 1996 in the same area. From 21 January 1997, through 18 October 1997, 15 earthquakes occurred with Ms ≥ 5.0, seven of which with Ms ≥ 6.0. Such sequences of strong earthquakes are rare around the world, but have occurred six times in the land area of China during this century. Of the 15 Ms ≥ 5.0 earthquakes in the Jiashi sequence, eight fell within the predicted 7-day time windows of a total of 8 short-term and imminent-stage predictions, but the initial shocks of the sequence (January 21, Ms 6.4, 6.3) were not predicted. Three of the eight predictions made were not fulfilled, one of which was announced to the public (a false alarm). Four of the remaining five predictions were acted on by local authorities and the public was notified 2.5 h to 4 days before the earthquakes, which caused no deaths. One earthquake (April 11, Ms 6.6) struck 30 min after the prediction was made but before action could be taken by the local authorities, and it caused nine deaths. These predictions were based on composite observations of precursory anomalies in seismicity, electromagnetic fields, and crustal deformation, which were in turn compiled over the past 30 years in a nationwide earthquake monitoring program. Examples of precursory anomalies include: (1) a clear seismicity pattern of “quiescence—intensification—main shock(s)” was observed for the April 6 earthquakes (Ms 6.3, 6.4), which was previously applied to the prediction of the well-known 1975 Haicheng earthquake in Laoning, China; (2) distinct decreases in b-values preceded the earthquakes on March 1 (Ms 6.0) and April 6 (Ms 6.3, 6.4); (3) anomalous variation of geomagnetic vertical component preceded the April 6 earthquakes (Ms 6.3, 6.4); (4) sudden decreases in borehole strain preceded 8 of the earthquakes.
Tectonic setting of the 1971 Sylmar and 1994 Northridge earthquakes in the San Fernando Valley, California
Authors: Tsutsumi Hiroyuki , Yeats Robert S. 
Published: November 2022

AbstractThe San Fernando Valley lies above the north-dipping 1971 Sylmar and south-dipping 1994 Northridge earthquake faults. To understand the tectonic setting of these two earthquakes, we mapped subsurface geology of the San Fernando Valley down to a depth of ∼3 km, using industry oil-well and seismic data. The 1994 Northridge earthquake did not rupture the surface, and the south-dipping aftershock zone terminated against the north-dipping 1971 aftershock zone at a depth of 5-8 km. However, the blind Northridge fault has a near surface geologic expression; fault-propagation folding related to the Northridge fault has preserved a thick forelimb sequence of Plio-Pleistocene Saugus Formation in the Sylmar basin and Merrick syncline, which are located on the hanging wall side of north-dipping reverse faults. The north-dipping Mission Hills, Verdugo, and Northridge Hills reverse faults are interpreted to be potential seismic sources because fault-propagation folds above these faults have tectonic geomorphic expression. These north-dipping reverse faults were initiated during the deposition of the Saugus Formation between 2.3 and 0.5 Ma. and have minimum dip-slip rates of 0.35 to 1.1 mm/yr based on the oldest possible age of the initiation of faulting. The Northridge Hills and Mission Hills faults are interpreted to merge at depth and are located at the updip extension of the 1971 aftershock zone, even though these faults did not rupture during the 1971 earthquake. Surface breaks appeared north of these faults mostly along north-dipping bedding planes and are interpreted as secondary features related to flexural-slip folding rather than a direct extension of the 1971 seismogenic fault. Surface and subsurface geology, together with seismological data of the 1971 and 1994 earthquakes, suggests that the north- and south-dipping deformation zones in the San Fernando Valley are divided into multiple segments separated by northeast-trending structural discontinuities.
Estimating prehistoric earthquake magnitude from point measurements of surface rupture
Authors: Hemphill-Haley Mark A. , Weldon Ray J. 
Published: November 2022

AbstractWe have developed a method for estimating the magnitude of prehistoric earthquakes using displacement data that usually can be collected from paleoseismic investigations. This method is necessary because essentially all current magnitude estimates for prehistoric events rely on determining the total length of coseismic surface rupture, which is rarely measurable, or rely on segmentation scenarios, for which uncertainties cannot be quantified. Although surface rupture length is a better predictor of magnitude than displacement for historic earthquakes, paleoseismic investigations are better at providing measurements of the amount of displacement at a site along a fault. The key to our method is to incorporate the variability in displacement observed in 14 modern events, which allows a formal uncertainty in magnitude to be assigned to prehistoric ruptures. We show how multiple measurements along a preserved fraction of a rupture can be combined to reduce the uncertainty in the estimate of magnitude. Our analysis shows that uncertainty asymptotically approaches the natural variability of ruptures, so 5 to 10 displacement measurements are sufficient to characterize paleomagnitude. We conclude that sampling of scarps with lengths of even 10% of the original rupture can provide magnitude values that reasonably estimate the earthquake. Tests of the method, using randomly sampled data from the 1992 Mw 7.3 Landers and 1954 Ms 6.8 Dixie Valley earthquakes, provide close approximations of the actual magnitudes.
NOTAS REPRODUCTIVAS DE COLACINTILLO COLINEGRO Lesbia victoriae (APODIFORMES: TROCHILIDAE) EN QUITO, ECUADOR
Authors: Narváez Izurieta Rafael Wilson 
Published: November 2022

Resumen.- Realicé observaciones directas a siete nidadas de Lesbia victoriae entre 2016 a 2020 en el jardín de mi casa, en Quito. Hice seguimiento a tres nidos uno de los cuales tuvo cinco nidadas consecutivas. Las hembras después del cortejo, construyen los nidos, ponen dos huevos, los pichones nacen desnudos y abrieron los ojos a los 17 días, la hembra queda asentada en el nido entre los 13 - 15 días, incuba entre los 18 - 19 días. Los volantones están listos para volar a los 25 - 27 días y los volantones no presentan dimorfismo sexual. Este estudio presenta información actualizada de la biología reproductiva de Lesbia victoria en un ambiente urbano.
Palabras claves: anidación, ciudad, eclosión, incubación, nidos, pichones.
NESTING BIOLOGY OF AN ECUADORIAN ENDEMIC HUMMINGBIRD, THE ENDANGERED VIOLET-THROATED METALTAIL Metallura baroni
Authors: Carrasco Ugalde Agustín , Molina Paúl , Pacheco Daniel , Tinoco Boris 
Published: November 2022

Violet-throated Metaltail Metallura baroni is a threatened hummingbird species, endemic to the Andes of southern Ecuador. Details about the reproductive biology of this species are largely unknown. In this manuscript, we describe the nest, eggs, and nestlings"™ development based on nine nests found along with the Cuenca-Molleturo-Naranjal road, in Cajas National Park, in 2019. We document a breeding period from March to May, which corresponds to the rainy season. All nests were found in roadside embankments, and were constructed with mosses, small twigs, rootlets, Polylepis sp. (Rosaceae) bark, and Puya sp. (Bromeliaceae) fibers. In all nests, we found two white oval eggs that were exclusively attended by a female across the breeding period. Hatching to fledging period lasted 28-32 days. Nesting at roadsides can be particularly risky due to a high probability of collision with vehicles; thus, an assessment of the breeding success of M. baroni on nests located at roadsides is a research priority for this species. The information provided here increases the knowledge about the natural history of M. baroni.
REGISTRO DE LA AGUJETA PIQUILARGA Limnodromus scolopaceus (SCOLOPACIDAE) DESPUÉS DE 89 AÑOS EN LA LAGUNA DE COLTA
Authors: Arteaga-Chávez William Andrés , Ocaña Edison , Hipo Rolando , Santander Tatiana 
Published: November 2022

La Agujeta PiquilargaLimnodromus scolopaceus (Scolopacidae) se reproduce principalmente en el norte de América del Norte y migra hacia el sur de América del Norte y América Central durante el invierno boreal. En Ecuador son muy escasos los registros y se considera un visitante accidental. En esta nota presentamos el segundo registro de L. scolopaceus en la laguna de Colta, provincia de Chimborazo, luego de 89 años. Este registro representa la primera observación de campo en Colta, ya que el registro previo corresponde a un espécimen, y es la segunda vez que se observan varios individuos juntos en Ecuador. Los registros consecutivos en 2018-2020 en otros sitios del Ecuador continental podrían indicar que esta especie actualmente es un visitante más frecuente.
Política migratoria en las islas Canarias: violaciones de derechos humanos durante la pandemia
Authors: Rodríguez Salinas Roberto 
Published: November 2022

La inmigración irregular es un fenómeno complejo que desafía los conceptos de confinamiento y restricción al libre tránsito presentados por la pandemia. En ese sentido, 2020 fue un año particularmente agitado para los flujos migratorios de África a Europa. La ruta hacia las islas Canarias en España se reactivó luego de más de una década de baja actividad, llegándose a registrar 23 023 llegadas irregulares en 2020. Al igual que en otros territorios insulares europeos, como Lesbos o Lampedusa, Canarias cuenta con una limitada capacidad estatal de atención al inmigrante. La pandemia representa, entonces, un factor para la emigración masiva en el Magreb y África subsahariana, pero también es un factor para la violación de derechos humanos de los inmigrantes antes, durante y después de su llegada al archipiélago canario. En estas circunstancias, el Estado español está obligado a cumplir con el derecho internacional, comunitario y nacional en lo referente a los derechos fundamentales de las personas migrantes. Este artículo argumenta que España debe garantizar en todo momento la protección de la salud de los refugiados y solicitantes de protección internacional en los procedimientos legales de intervención, atención y detención. Asimismo, la aplicación de medidas sanitarias no exime al Estado de su obligación a brindar garantías como el acceso a la asistencia letrada, la libre circulación por todo el territorio, el respeto por los plazos de detención y el mantenimiento de las instalaciones de recepción
La educación a distancia: sus características y necesidad en la educación actual
Authors: Martínez Uribe Carmen Heedy 
Published: November 2022

El presente artículo destaca la relevancia de la educación a distancia mediante la identificación de sus características, y haciendo referencia a las diferencias existentes con la educación presencial. Del mismo modo, precisa los conceptos de educación virtual y e-learning, y aborda el rol e importancia de las tecnologías de la información y las comunicaciones (TIC) en esta modalidad educativa. Por otro lado, el texto incide en reconocer los alcances de esta modalidad en el ámbito de la educación superior.
La evaluación formativa-colaborativa para la construcción del aprendizaje en los alumnos de arte y diseño
Authors: Hermoza Samanez Luz Marina 
Published: November 2022

Los objetivos de la experiencia que presentamos son: a) identificar los logros del aprendizaje de los alumnos del curso de Dibujo Geométrico (DG) 1 y 2 de la Facultad de Arte de la Pontificia Universidad Católica del Perú (PUCP) construidos durante la evaluación del aprendizaje. Asimismo, b) demostrar cómo el enfoque de la evaluación formativa apoya la construcción de autonomía y autorregulación del estudiante de arte, capaz de ser consciente de su propio desarrollo y de hacer una autocrítica de su producción artística, basada en criterios objetivos que él mismo va a descubrir y conceptualizar, mientras va adquiriendo herramientas procedimentales y conceptuales para el desarrollo de técnicas de dibujo y de su propia expresión. De esta manera impulsa la formación de un carácter fuerte para la evaluación crítica, entendida aquí como una estrategia específica de evaluacióndel arte y el diseño.También reflexionaremos sobre la implementación de estrategias de evaluación orientadas hacia lo colaborativo, para darle significancia a la forma y a los contenidos destinados al aprendizaje, mientras el alumno adquiere herramientas para el desarrollo de técnicas de dibujo y de su propia expresión. Las estrategias de evaluación están orientadas a la autorregulación del alumno ya que simultáneamente al área conceptual, pondrán en práctica metodologías diversas y experimentarán estrategias de aprendizaje colaborativo e individual orientados alaprender a aprender y al aprender a ser.