bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalencia de morbilidad neonatal
Authors: Delgado Bernal Doris Susana , Bravo Bonoso Delia Georgina , López Miladys Placencia , Sidar Edgardo Solorzano Solorzano 
Published: January 2022

Cada año nacen unos 15 millones de niños prematuros y la tasa de estos nacimientos está entre el 5% y el 18%, las complicaciones relacionadas con la prematuridad es la principal causa de defunción en los niños menores de 5 años; en Manabí-Ecuador en el año 2019 hubo 106 muertes neonatales, de ellos 55 de género masculino (52%), y 50 de género femenino (48%), de estas muertes 73 (69%) fueron dentro de los primeros 7 días de vida, de ellas 20 (28%) en las primeras 24 horas ; de vida, la mortalidad neonatal tardía fue de 33 neonatos (31%). La tasa de mortalidad neonatal es de 5.43 en Manabí por 1000 nacidos vivos. El objetivo de esta investigación fue identificar la prevalencia de ingresos de neonatos por múltiples complicaciones. Se realizó un estudio analítico deductivo, retrospectivo, no experimental, en neonatos ingresado por múltiples morbilidades. Se concluye que los factores de riesgo de prevalencia en las morbilidades neonatales son; ruptura prematura de membrana, madres adolescentes, prematurez, escasos controles prenatales, baja condición socio-económica y analfabetismo. En los resultados, las complicaciones que se presentaron con frecuencia fue: el síndrome de dificultad respiratoria, ictericia neonatal, sepsis neonatal, bajo peso al nacer, recién nacido prematuro, taquipnea, sífilis congénita y asfixia.
Determinantes sociodemográficos y ambientales en la prevalencia del dengue en la zona urbana de Jipijapa
Authors: Pincay Pin Virginia Esmeralda , Pincay Reyes Yomaira Stefania , Villacreses Veliz Geoconda , Villegas Chiriboga Margoth Elizabeth 
Published: January 2022

El dengue es un problema para el sector de la salud pública debido al número de casos que se confirman cada año de acuerdo a datos estadísticos. ¨El aporte en la prevención es publicar la investigación¨ El objetivo de la investigación, examinar los determinantes sociodemográficos y ambientales en la prevalencia del dengue en la zona urbana de Jipijapa. La metodología empleada fue observacional, descriptiva, retrospectivo, analítico. Se empleó técnicas cualitativas y cuantitativas. La población de estudio: setenta personas, aplicando una encuesta de catorce ítems las cuales fueron dirigidas a pacientes, familias y vecinos diagnosticados con dengue, se ejecutaron entrevistas dirigidas a profesionales especialistas en el tema, se realizaron visitas domiciliarias en los distintos sectores de la zona urbana de Jipijapa donde se encontró varios determinantes sociodemográficos y ambientales que influían de forma directa en la proliferación de mosquitos, se destacó la presencia de maleza en los terrenos baldíos, contaminación de ríos, deficiencia en los hábitos de higiene en el hogar. Los resultados obtenidos en la investigación determinaron que la población más susceptible son los niños predominando el sexo femenino, se concluye que los sectores que presentaron los casos de dengue con y sin signos de alarma, son urbanos marginales, entre ellos la ciudadela Eloy Alfaro, Cristo del Consuelo, San Vicente, estos poseen los servicios básicos, sin embargo, existe un déficit de conocimiento, al momento de realizar la visita domiciliaria en los casos confirmados aún persistían receptáculos contaminados con los huevos y larvas del mosquito debido a una limpieza inadecuada.
La obesidad como factor de riesgo de la hipertensión arterial
Authors: Flores Hidalgo José Jordano , Guerrero Dueña María Auxiliadora , García Rodríguez Reynier 
Published: January 2022

La investigación se basa en la incidencia de la obesidad como factor de riesgo para la hipertensión arterial (HTA) abarcando el análisis de variables de dichos padecimientos, puesto que ambas constituyen factores de riesgo para la salud de las personas. En América Latina, Ecuador es el país que mayor prevalencia posee de HTA debido a que se registra un incremento de motivos de consulta en los centros hospitalarios por HTA en mayor parte en las provincias de Guayas, Pichincha y Manabí y a su vez se estima que 6 de cada 10 adultos poseen sobrepeso u obesidad. Siendo el objetivo del presente trabajo determinar la incidencia de la obesidad como factor de riesgo de la hipertensión en los habitantes de la Ciudadela “Libertad” del cantón Portoviejo en el periodo comprendido de mayo-agosto de 2020. Se realizó un estudio no experimental, inductivo-deductivo y transversal a 50 personas. Datos los cuales fueron organizados en una base de datos mediante Microsoft Excel. Finalmente, se obtiene que los datos de la población investigada poseen aspectos positivos y negativos para la salud de las personas. Para el primero se destaca la Frecuencia de Actividad Física y para el segundo los controles médicos y el tratamiento, los cuales representan un porcentaje bajo para lo esperado.
Oncobox molecular profiling for a patient with recurrent endometrial cancer
Authors: Seryakov A. P. , Akhmaev R. M. , Guryanova A. A. , Prokofieva A. A. 
Published: January 2022

Relevance. Endometrial cancer (EC) is the most common gynecological tumor. As a rule, it has a good prognosis, but in case of relapse, it worsens significantly. The effectiveness of cytotoxic chemotherapy for the treatment of such patients remains low.Purpose. To present a clinical case demonstrating the possibilities of therapy performed according to the results of molecular profiling of the tumor by RNA sequencing methods.Methods. Analysis of the anamnesis data, the results of histological and immunohistochemical studies, PET-CT, ultrasound images, and RNA sequencing data was carried out. The results of therapy prescribed in accordance with the rating of targeted drugs obtained after processing the transcriptomic profile by the Oncobox diagnostic platform were evaluated.Results. After experimental second-line therapy, a partial response was recorded.Conclusion. Early molecular profiling and therapy assignment in accordance with its results can change the course of the disease and improve the quality of life of patients.
The Story of Coraline(s): A Gothic Coming of Age
Authors: Torres-Fernández J. Javier 
Published: January 2022

This study deals with Coraline (2002), the novel by Neil Gaiman, and Coraline (2009), the animated adaptation directed by Henry Selick based on Gaiman’s book. While Gothic stories often emphasize and question human morality, children’s literature usually holds a moralizing value. Neil Gaiman’s Coraline presents a story within the genre of children’s literature that seems to be deeply rooted in the Gothic tradition. Some of the fundamental gothic elements in Coraline’s story are the presence of ghosts, grotesque beings, and the existence of a parallel and dark universe that serves as the setting for the story. Coraline deals with anxieties related with personal development, growing up, and the environments that surround her. Gothic content within both the book and the film contribute to the undermining of the idealization of Coraline’s family, her own process of growing up, and her coping with moving to a completely different place. The creation of the gothic world is exploited in both works to represent Coraline’s coming-of-age experience and her conflict with her family. However, despite Selick’s film being a faithful and well-delivered adaptation of Gaiman’s novel, there are considerable differences that affect how the audience interprets Coraline as a character and her story, which this analysis will highlight.
Impact of Financial Literacy Levels among Sri Lankan Investors on Investment Choices
Authors: Tennekoon S. T. M. S. , Liyanage C. 
Published: January 2022

Purpose: The purpose of this study is to investigate the level of financial literacy among Sri Lankan investors and its impact on investment choices. Design/methodology/approach: The population of this study consisted of the individual investors of Sri Lanka. Accordingly, a sample of 352 responses were obtained through a survey which was conducted using structured self-administered questionnaire. The independent variable of the research is financial literacy with the dependent variable being the investment choice. Multinomial logistic regression was used to test the hypothesis. Findings: The results of the study revealed that the majority of investors in Sri Lanka are having low objective and subjective financial literacy. Further, the results revealed that financial literacy has a statistically significant impact on the current and future choice of different investment products as the main source of investment. Originality: Financial literacy level of individual investors was assessed by using the mean value of the financial literacy score, which has not been commonly used in the Sri Lankan context. This study further contributed to the local body of literature by analyzing the investors’ current main and secondary holdings of seven different investment products and their future investment preference towards these products.
Psycho-Social Correlates of Dental Anxiety and its Association with Caries Experience In 12-16-Year-Old School Going Children in Southern India
Authors: Singh Sweta , Acharya Shashidhar , Bhat Meghashyam , Chakravarthy P Kalyan , Kariya Pratik 
Published: January 2022

Introduction:
Dental anxiety causes a decrease in population addressability to the dentist with antagonistic consequences for long-term oral health. Assessment of behavioural factors that correlate with dental anxiety is important for the accurate evaluation of dental fear. Its diagnosis in childhood is important for establishing therapeutic management strategies to reduce anxiety and promote oral health.

Materials and Methods:
A sample of 289 children of ninth and tenth grades from two public and two private schools of Udupi town was drawn. Two-stage sampling was used for the enrolment of students. A pre-tested self-administered questionnaire was used for the collection of data on psychological aspects, socioeconomic background and health behaviours. Dental anxiety was assessed using a translated version of the modified dental anxiety scale (MDAS). Oral examination was done for the assessment of dental caries using the decayed, missing, filled teeth index.

Results:
Students from public schools showed a significantly high prevalence of dental anxiety and also higher scores. Dental phobia was significantly more in children from public schools. Female gender, lesser brushing frequency, fewer previous dental visits and lower socioeconomic status were significantly associated with higher dental anxiety levels. In addition, the caries experience was significantly higher in children from public schools.

Conclusion:
Socioeconomic background and social environment in the school play an important role in overcoming dental anxiety and practising healthy behaviour and therefore should be considered to break the vicious cycle of dental anxiety and poor dental health.
Congenital Pouch Colon in Girls
Authors: Gupta Amit , Kumar Amit , Chadha Rajiv , Yadav Partap Singh , Khanna Vikram , Choudhury Subhasis Roy 
Published: January 2022

Aim:
The aim of the study was o define the preoperative diagnostic clinical and radiological features in girls with congenital pouch colon (CPC).

Materials and Methods:
Records of 47 girls with CPC, managed from 1996 to 2018, were reviewed. There were two age groups: Group A (newborn to 12 months; n = 26) and Group B (>12 months to 20 years; n = 21). The important clinical and radiologic features to help in a preoperative diagnosis were noted.

Results:
The most common subtype was Type II (57.4%), followed by Type I (23.4%) and Type III (12.8%). The features common to both the groups were abdominal distension (A = 53.8%; B = 9.52%), severe perineal excoriation (A = 19.2%; B = 23/8%), and urinary incontinence (A = 30.7%; B = 85.7%). In addition, in Group B, fecaloma on abdominal palpation was noted in 28.6% of patients. The characteristic appearance of the perineum including external genitalia and findings on plain abdominal X-ray (AXR) were 100% accurate and hence diagnostic. These unique features helped us formulate an algorithm for preoperative diagnosis of this uncommon form of anorectal malformation in girls seen in North India.

Conclusions:
The characteristic features on clinical examination should alert one to the presence of CPC in the outpatient clinic. The AXR was diagnostic in 100% of cases and is mandatory. If any doubt persists, examination of the genitalia under anesthesia with more retraction of the labial folds and endoscopy can be performed for confirmation. These measures should enable a clinician to make an accurate preoperative diagnosis in every girl with CPC.
Utility of Urinary Biomarkers Neutrophil Gelatinase-Associated Lipocalin and Kidney Injury Molecule-1 as a Marker for Diagnosing the Presence of Renal Scar in Children with Vesicoureteral Reflux (VUR)
Authors: Naik Prathibha B. , Jindal Bibekanand , Kumaravel S. , Halanaik Dhanapathi , Rajappa Medha , Naredi Bikash Kumar , Govindarajan KK 
Published: January 2022

Aim:
To explore the possibility of using urinary biomarkers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) to assess the presence of renal scars in children with Vesicoureteric Reflux (VUR).

Materials and Methods:
This cross-sectional study was conducted in 94 children aged 0–16 years diagnosed with VUR in the Department of Pediatric Surgery, JIPMER. Urinary biomarkers were measured using the enzyme-linked immunosorbent assay kits, normalized with urinary creatinine (Cr) and compared with severity of VUR (low grade [I and II] and high grade [III, IV, and V]), presence or absence of renal scar in VUR patients and severity of renal scar. Independent Student's t-test, Mann–Whitney U-test, and analysis of variance Kruskal–Wallis test were used for comparison, and receiver operating characteristic (ROC) curve analysis for predicting the accuracy of biomarkers in detecting the presence of renal scars.

Results:
The median urinary NGAL (uNGAL) value was higher in children with renal scar (1.49 ng/mL) than those without renal scar (0.58 ng/mL) and was statistically significant (<0.001). Whereas median uNGAL/Cr was higher in children with renal scar (0.07) than those without renal scar (0.03) but was not statistically significant (P = 0.06). Urinary KIM-1 and urinary KIM-1/urinary Cr (uKIM-1/Cr) was not found to be a significant predictor of renal scar. The difference of uNGAL/Cr was comparable between the grades of renal scar but was not statistically significant. On ROC curve analysis, uNGAL had area under the ROC curve (AUC) of 0.769 with 71% of both specificity and sensitivity, whereas uNGAL/Cr was found to be a poor predictor of renal scar with AUC of 0.611, 60% sensitivity, and 61.2% specificity.

Conclusion:
uNGAL can serve as a noninvasive marker for diagnosing the presence of renal scar in children with VUR and a multicentric more extensive cohort study may be needed to strengthen or negate its role.
Capitonnage method selection in pulmonary hydatidosis with purse-string or interrupted suture
Authors: Aydogmus U , Ugurlu E 
Published: January 2022

ABSTRACT

Background:
Disfigurements in the lung parenchyma due to capitonnage methods may lead to long-term atelectasis. The aim of the present study was to examine whether there are any complication differences between the capitonnage applied via interrupted suture or purse-string suture.

Method:
Of the total of 120 cases that underwent hydatid cyst surgery during 2007 and 2020, those that were subject to capitonnage were included in the study. The preoperative and postoperative findings were analyzed for 76 cases subject to purse-string capitonnage (Group I) and 24 interrupted capitonnage (Group II).

Results:
While the number of cases with complication in Group I was 16 (21.1%), there were only 2 (8.3%) complications in Group II; however, the difference was not statistically significant (P = 0.23). Bronchopleural fistula (n = 1) and prolonged air leak (n = 2) were observed in Group I, there was no bronchopleural fistula or prolonged air leak in Group II. Atelectasis was the most frequently observed complication observed in 12 (15.8%) cases in Group I and 2 (8.3%) cases in Group II (P = 0.53). The duration of hospitalization was lower for the patients in Group II. The number of days was 7.3 ± 2.7 for Group I and 5.3 ± 2.1 for Group II (P < 0.01).

Conclusion:
This study is the first to compare whether there are any complication differences between the capitonnage methods via interrupted suture or purse-string suture. The results of the study put forth that the duration of hospitalization is lower in the interrupted capitonnage group. Parenchymal anatomy may be preserved better in interrupted capitonnage method.
A novel technique in septal perforation
Authors: Hanci D , Gurpinar B , Sari H , Uyar Y 
Published: January 2022

ABSTRACT

Background:
Nasal septum perforation (NSP) is an anatomical defect of the mucosa, cartilage/bone of nasal septum and septoplasty is the most common cause of it. A perforated septum rarely heals on its own, it is more likely to get worse. The success for large perforations is approximately 78%, it is harder to be successful in vertically larger perforations. We introduce a new technique to close large perforations by the fascia lata and costal cartilage sandwich graft (FLSG). The main advantage of this technique is that the fascia lata eliminates the opening between the septal mucosal flaps in case the septal mucosal flaps may not meet each other.

Patients and Methods:
16 cases presenting with nasal septum perforation were repaired with the FLSG technique. Grafts were harvested, the perforation was accessed through open rhinoplasty approach, FLSG is inserted and sutured.

Results:
16 cases consisting of 9 males (56.25%) and 7 females (43.75%) were operated. The age range was between 20 and 43 years (mean 32.6 ± 6.94). 3 cases (18.75%) had medium and 13 cases (81.25%) had large NSP. 8 cases (50%) were smokers. Nine month postoperatively, all medium NSP were closed. During this period, 14 NSP (87.5%) medium size NSP achieved complete closure, while the remaining two NSP that were yet to close had large defects (>2 cm) and smokers.

Conclusion:
FLSG is an effective, easy, and novel technique in NSP repair and the postoperative controls have proven a high success rate even in large NSP.
Spontaneous space closure following the extraction of the first permanent mandibular molar
Authors: Çiftçi V , Güney AU , Deveci C , Sanri IY , Salimow F , Tuncer AH 
Published: January 2022

ABSTRACT

Aim:
The aim of this study was to determine the prognostic factors, such as the developmental stage of second permanent molar (SPM), the angulation of SPM, and presence/absence of the third molar associated with the spontaneous space closure after the mandibular first permanent molars (FPM) extraction.

Material and Methods:
A total of 177 mandibular SPMs were evaluated in this cross-sectional study. The prognostic factors determining successful space closure such as SPM developmental stage, SPM angulation, and presence/absence of the third molar were evaluated.

Results:
The mean age of the patients at the time of extraction of SPM was 9.4 years and post-extraction assessment at the time of the study was 12.7 years. Of the total 177 mandibular SPMs, 36 SPMs (20.3%) were at Demirjian stage D, 63 (35.6%) at stage E, 60 (34%) at stage F, 18 (10.1%) at stage G. 18 SPMs (10.1%) had distal angulation, 23 SPMs (13.0%) had mesial angulation and 136 SPMs (76.9%) had upright angulation. At the time of radiographic assessment, 79.1% of the mandibular quadrants showed evidence of third molar formation. Of the 177 mandibular SPMs, 93 (52.5%) exhibited successful space closure in the mandibular arch.

Conclusions:
There is no statistical significance between the chronological age and the developmental stage of the mandibular SPM with regard to the successful spontaneous space closure at the time of the dental extraction of FPMs. The presence of the mandibular third molar may be a consideration for spontaneous space closure in the mandibular arch.
Knowledge and attitude regarding bisphosphonates and related osteonecrosis among Turkish dentist
Authors: Özkan E , Bereket MC , Özkan N 
Published: January 2022

ABSTRACT

Background and Aims:
Bisphosphonates (BPs), the antiresorptive drugs, can cause osteonecrosis of the jaws. Having adequate knowledge about BPs and bisphosphonate-related osteonecrosis of the jaw (BRONJ) is very important to prevent complications. In this study, we aimed to determine the level of knowledge of dentists about BPs and BRONJ in Turkey and also aimed to share the results with health authorities to plan new education strategies.

Materials and Methods:
A questionnaire consisting of 20 questions and two parts was used to determine the knowledge level, attitude, and training needs of the dentists. Answers to all questions were analyzed with descriptive statistics, and using Pearson Chi-square and Kruskal–Wallis tests. P values <0.05 were considered statistically significant.

Results:
A total of 620 general and specialist dentists working in three different sectors and four different cities agreed to participate in the study. Statistically, more knowledge about BPs and BRONJ was observed in dentists who have less than 10 years of experience than those who have over 10 years, specialist dentists than general dentists, and those who working in university hospitals than in other sectors. In general, the rate of those who know BPs is 16.8%, the rate of those who know BRONJ is 20.2%.

Conclusions:
Although the use of BPs increases day by day, the awareness of BPs and BRONJ among the dentists is insufficient. However, periodically organizing postgraduate training programs on this subject will increase the awareness and level of knowledge.
Impact of COVID -19 Pandemic on Plastic Surgery Practices in a Tertiary Care Set Up in Southern India
Authors: Chellamuthu Abiramie , Kumar J Sathish , Ramesh BA 
Published: January 2022

ABSTRACT

Background:
The COVID-19 pandemic has modified the way, plastic surgeons treat their patients. This article depicts how we as a plastic surgery department in a tertiary care setup handled the pandemic with an emphasis on infection control policy.

Methods:
Data was collected from hospital records and quality assurance cell from March 21, 2020 to June 19, 2020 in terms of patient triaging, consultations, perioperative protocols, duty rosters, and academic activities. The changes on these with the impact of COVID-19 were studied with the same period of previous year.

Results:
Outpatient clinics were closed and emergency consultations were reduced. Number of consultations reduced from 2591 to 75 and surgeries from 320 to 46 during the same period in 2019 and 2020 respectively. Though tele-consultations were helpful, the overall benefits were subpar. Emergency services continued with the guidelines of institute's infection control committee, such as area specific personal protective equipment, allotment of operating rooms, minimizing the crowd in operating room. There was some compromise in using accessories for microsurgical procedures. Duty rosters were designed to maintain uninterrupted services. Academic activities were continued with virtual platforms.

Conclusion:
Adequate preparation of health care setup and nation-wide lockdown has helped to handle emergency cases and in reduction of trauma-surgeries respectively. Though there were obstacles for some patients in accessing health care, our institutional response made us to render maximum possible care. Advancements in virtual platform helped in consultations and academics. Delayed conservative approach was used in most cases at the expense of cosmetic compromise.