bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementasi Model ATIK untuk Meningkatkan Literasi Numerasi Menggunakan Bahan Loostpart di TK Mutiara Setu
Authors: Mulyati Evi , Watini Sri 
Published: February 2022

Literasi numerasi sebagai pengetahuan dan kecakapan yang erat kaitannya dengan pemahaman angka, simbol dan analisis informasi kuantitatif (grafik, tabel, bagan, dan sebagainya), sangat penting dipelajari generasi saat ini. Untuk itulah guna meningkatkan literasi numerasi menggunakan bahan loostpart melalui “Model ATIK” . Model Atik adalah singkatan dari Amati, Tiru, kerjakan. Loose part adalah media material lepas yang penggunaannya dapat beragamMetode yang digunakan dalam penelitian ini adalah metode Penelitian Tindakan Kelas atau PTK. Metode Penelitian Tindakan Kelas adalah Penelitian yang mengkombinasikan prosedur penelitian dengan tindakan subtantif .Model proses dalam penelitian tindakan kelas menurut Kemmis dan Taggart. Adapun Sasaran dalam penelitian ini adalah anak usia 5-6 tahun. Diperoleh dari hasil penelitian tindakan kelas di TK Mutiara dengan jumlah siswa sebanyak 15 anak, diperoleh setelah menerapkan suatu Penerapan Model Atik untuk meningkatkan literasi Numerasi menggunakan bahan Looosepart setelah melakukan tindakan dari siklus I sampai pada siklus III, pada tindakan siklus I membahas materi tentang “Manfaat bahan looseparts pada peningkatan literasi Numerasi anak”, belum menampakkan hasil secara maksimal setelah dilaksanakan evaluasi. Pada perlakuan siklus II terjadi adanya peningkatan hasil dalam meningkatkan literasi Numerasi, dalam proses penelitian menggunakan model ATIK terbukti efektif dalam meningkatkan literasi numerasi dengan menggunakan bahan loosepart pada anak TK Mutiara.
IMPROVE LISTENING ABILITY THROUGH DICTATION METHODOLOGY IN DESCRIPTIVE TEXT AT SMK HKBP PEMATANGSIANTAR
Authors: Sitanggang Anita , Panjaitan Anne Silvia , Sinaga Ita Christine , Siburian Ruth Junisa 
Published: February 2022

This research aims to improve listening ability students of English subjects using the dictation method and find the effectiveness of the dictation method in an effort to improve ability listening to students on descriptive text of class X IA 1 students of SMK HKBP PEMATANGSIANTAR. This research is a classroom action research conducted in the first semester of the year 2021/2022 teaching. The subjects of this research were students of class X IA 1 SMK HKBP PEMATANGSIANTAR. The object of this research is the improvement of listening ability English lessons on descriptive text with the dictation method. Classroom action research it covers 2 cycles. Each cycle consists of four stages, namely: (1) planning, (2) action, (3) observation, and (4) reflection. The findings from classroom action research are (1) Students' listening ability increase with the use of the dictation method, (2) The average score of students in the pre-cycle action is 56.84% including the "less" category, the average student score in cycle 1 is 70.47% including the "enough" category, the average student score in cycle 2 is 78.43% including the "good" category. (3) Attainment of listening competence skill is measured by the dictation method which shows an increase in the results of research from pre-cycle to cycle II.
PROBIOTIC AND NUTRITIONAL CONTENT OF SOURO, AN IRANIAN TRADITIONAL FOOD
Authors: Mohkam Milad , Ghasemi Firoozabadi Shiva , Ghasemi Younes , Gholami Ahmad 
Published: February 2022

Probiotic foods are products containing adequate amounts of live and specific microorganisms that confer benefit to human health. This research was performed to spotlight on the nutritional value evaluation as well as isolation and probiotic characterization of lactic acid bacteria (LAB) isolated from native food "Souro" belonging to Iran. The isolated LABs were investigated in vitro for potential probiotic features based on their acidic pH tolerance, bile-salt resistance, hydrophobicity, autoaggragation, production of amylase and protease as well as antibiotic susceptibility test. Results showed that Souro had high content of protein (51 ± 0.16%,) and total lipid was 11.18 ± 0.38%. Most of isolates were able to produce protease and amylase. From the best potential probiotic isolates, 16S rRNA gene sequencing disclosed Lactobacillus plantarum, L. hilgardii, L. casei, L. fermentum and Weissella paramesenteroides. Thus, good physiological traits and safety evaluation of the isolated LAB emphasized the benefits of Souro for further use in the human diet as well as the preparation of diverse probiotic food formulations.
SUBTILISIN AN EMINENT MICROBIAL PRODUCT AS A POTENTIAL SKIN CARE REGULATOR OF MELANOGENESIS –A PARADIGM SYNCHRONIZED WITH IN VITRO / IN SILICO APPROACH
Authors: Margret Arockiya Anita , Nivetha Irulandi , Jerley Arockiya Avila , Aishwarya S 
Published: February 2022

Colour is considered as a foremost parameter for physical appearance and personal identification. The distinct coloration of skin, hair and eyes of humas are categorized based on the natural pigment melanin which is the final product of melanogenesis. Melanin establishes a primary protection to the skin by inducing photo protection. But the rapid mechanism of absorbing free radicals from the cytoplasm is defensive against UV light, thereby its enormous production and accretion leads to perturbing skin ailments. During the process of melanogenesis the core enzyme tyrosinase is employed and moderated by a main transcription factor called microphthalmia associated transcription factor (MITF), which is enhanced by both tyrosinase-related 1 and 2 proteins (TRP-1 /TRP-2). Amending this physiological process is considered to be the foremost mechanism in improving skin fairness. Conversely, there are numerous cosmetics commercially available to depigment skin colour, the alarm of adverse effects and reoccurrence of hyperpigmentation prevails as a hitch. Synthetic skin products cause remedy with adverse effects and hence there is a high demand for novel skin colouring agent. This work lays a pedal stone in promoting the appliance of a naturally derived protein subtilisin secluded from soil isolates of Bacillus sp. in cosmetic industry as skin whitening aspect. The extraction of subtilisin was detected by biochemical and HPLC assays coordinated with anti-melanogenesis activity by in vitro studies. Further, synchronization of molecular docking studies hoisted the protein as an effective ligand targeting TRP1 and TRP2 with energy minimization of -675569 KJ/Mol and -36957KJ/Mol.
PECULIARITIES OF FORMATION AND FUNCTIONING OF THE SOYBEAN–BRADYRHIZOBIUM JAPONICUM SYMBIOTIC APPARATUS IN RELATION TO PHOTOSYNTHETIC ACTIVITY UNDER THE INFLUENCE OF SEED PROTECTANTS
Authors: Kots Serhii , Kiriziy Dmytro , Pavlyshche Anastasiia , Rybachenko Liliia 
Published: February 2022

The aim of work was to investigate the influence of seed treatment with two preparations of fungicidal action, differing in the active substances composition, on the formation and functioning of legume-rhizobial symbiosis in interaction with the photosynthetic apparatus of soybean plants. It was established that in plants treated with preparation Fever, the nitrogen-fixing activity (NFA) difference with the control was insignificant, but under the impact of the preparation Standak Top NFA was by 63% less at the stage of three true leaves, by 48% – at the stage of budding, and by 34% – at the stage of budding–flowering. The net photosynthetic rate, calculated per leaf area unit, was lower than control at all investigated stages of soybean plants development in the variants with the seed protectants applying. A fairly close positive correlations (R2 = 0.79) were observed between the average weight of one nodule and its NFA, and between the last and total NFA of the whole plant (R2 = 0.78). Close correlations between plant NFA, chlorophyll content in leaves, and net photosynthetic rate were revealed. It was concluded that seed protectants significantly influenced on nitrogen fixation and photosynthesis.
The strength of manifestation, and the sign of this influence in comparison with the relevant parameters of the control plants depended on the preparation, the stage of plant development, as well as on the index (nodules formation, nitrogen-fixing activity, photosynthetic, chlorophyll content, chlorophyll index, biological productivity of soybean plants) under consideration.
A REVIEW OF CURRENT KNOWLEDGE AND GAPS ABOUT CAMPYLOBACTER METHODS: FROM CULTURE TO CHARACTERIZATION
Authors: El Baaboua Aicha , El maadoudi Mohamed , Bouyahya Abdelhakim , Kounnoun Ayoub , Bougtaib Hajar , Omar Belmehdi , Boujida Nadia , Abrini Jamal 
Published: February 2022

Campylobacteriosis is a zoonotic disease caused by Campylobacter, mostly associated with consumption of contaminated foodstuffs and water. Campylobacter jejuni and Campylobacter coli recognized as the leader of foodborne diarrheal illness in humans. The frequency of these microorganisms in poultry is fairly high than Salmonella and more challenging to measure, which represent an expensive burden charge on public health due to their difficulties to master them, especially with the fast increase rates of multidrug-resistant of thermophilic Campylobacter strains. It is well recognized that Campylobacter spp. is a fastidious cell, difficult to isolate in laboratories owing to their requirements and sensibility. That’s why; these factors must be taken into consideration during recovery protocols. A variety of phenotyping tests have been reported and widely used for confirmation and identification of Campylobacter species. Nonetheless, Whole Genome Sequencing (WGS) and Culture-Independent Diagnostic Tests (CIDTs) are new eras of hopeful technologies, mainly involved in the detection and characterization of threaten public health pathogens. This review aimed to describe the culture methods, phenotypic and genotypic schemes used to isolate, identify, and characterize Campylobacter isolates, through discussing the current knowledge and gaps related to the application of these techniques over others performed for typing this microaerophilic genus.
BACTERIAL INHIBITORY EFFECT OF ALGERIAN POMEGRANATE (Punica Granatum L.) EXTRACTS (PEEL, JUICE, AND SEED) AGAINST MULTIDRUG RESISTANT BACTERIA
Authors: DEBIB Aicha , Menadi Soumaya , SAHNOUNI‎ Fatima , BOUKHATEM Mohamed Nadjib , OUAHCHIA Celia , KACED Amel 
Published: February 2022

Punica granatum L. (pomegranate) is known popularly by its nutritional values and healthy benefits. The current study is aimed the evaluation of antibacterial effects of Punica granatum fruit extracts that cultivated in Algeria against environmental and clinical isolates of β-lactamase producing methicillin resistant Staphylococcus aureus (MRSA) and extended-spectrum beta-lactamase ESBL-producing Enterobacteriaceae by using agar diffusion methods and minimum inhibitory concentration (MIC)-determination. Moreover, the extracts were investigated for their phenolic content by the Folin-Ciocalteu method. The quantitative assays of total polyphenols revealed a richness of the different pomegranate extract in polyphenols, peel and seed ethanol extracts contain the highest values (880.06 ± 11.2 mg GAE/100 g and 1160.1 ± 45.20 mg GAE/100 g, respectively). Flavonoid contents were high in both of acetone, ethanol extracts of peel, followed by ethanol, and acetone extracts of juice. According to the disc diffusion data, all phenolic extracts had a bacterial inhibitory effect against all extended-spectrum beta-lactamase ESBL-producing Enterobacteriaceae with a strong inhibitor with MIC 512 g/mL strength. The pericarp extract is particularly effective against Escherichia coli, Citrobacter freundii, and Klebseilla pneumoniae. However, the extract Punica granatum (pericarp and juice) revealed broad-spectrum antibacterial activity with an inhibitory diameter zone size of 11 0.9 mm to 29 1.12 mm against β-lactamase generating methicillin resistant Staphylococcus aureus (MRSA) species.These results were similar in both of agar diffusion and MIC methods. From the above study, it can be concluded that Algerian pomegranate extracts possess remarkable antibacterial activity. This result could be related to the presence of bioactive metabolites in this fruit. Therefore, intensive future studies should be performed to characterize the antibacterial components that are behind for this biological property.
FERMENTABLE OLIGOSACCHARIDES, DISACCHARIDES, MONOSACCHARIDES AND POLYOLS AND THEIR ROLE IN FOOD DIGESTION
Authors: Urminská Dana , Haring Nora , Fábry Vladimír , Urminská Jana 
Published: February 2022

Oligosaccharides containing fructose (fructans, inulin), galactose (galactans, stachyose, raffinose), disaccharides enclosing galactose (lactose), monosaccharides and mixtures of monosaccharides encompassing fructose (fruit sugar, honey) and saccharide polyols (mannitol, malbitol, sorbitol), are considered as safe to be consumed and beneficial to health. Gradually, however, their presence in the human diet reaches amounts that are indigestible by the small intestine, causing an osmotic load on the intestinal lumen. Subsequently, they pass into the large intestine, where they are fermented by intestinal bacteria to undesirable products such as gaseous carbon dioxide, hydrogen, methane, sulfane, and short chain fatty acids. Indigestible fermentable oligosaccharides, disaccharides, monosaccharides, and polyols may cause undesirable symptoms such as an increased flatulence, bloating, abdominal pain, alterations to the intestinal physiology, cessation of peristalsis, or diarrhea, which are manifested by a wide array of diseases of the gastrointestinal tract, such as the irritable bowel syndrome or small intestinal bacterial overgrowth. Fruits, vegetables, dairy products, legumes, some cereals, as well as honey or various sweeteners are among the most common food sources of these carbohydrates.
The ontogenetic pattern of Hippopotamus gorgops Dietrich, 1928 revealed by a juvenile cranium from the one-million-years-old paleoanthropological site of Buia (Eritrea)
Authors: MARTÍNEZ-NAVARRO Bienvenido , PANDOLFI Luca , MEDIN Tsegai , LIBSEKAL Yosief , GHINASSI Massimiliano , PAPINI Mauro , ROOK Lorenzo 
Published: February 2022

An almost complete cranium of a juvenile individual from the late Early Pleistocene site of Buia, in the northern Afar (Danakil) Basin in Eritrea, reveals a different growth pattern of the extinct species Hippopotamus gorgops Dietrich, 1928 compared to the extant species Hippopotamus amphibius Linnaeus, 1758. The specimen shows important cranial features of Hip. gorgops (also visible in adult specimens), with a derived cranial anatomy that is related to the specialization to a more aquatic life style than other species of Hippopotamidae: elevated nuchal and sagittal crests, strongly elevated orbital cavities, short neurocranium and elongated palate. A geometric morphometrics analysis was performed in the lateral view on skulls of Hip. gorgops and Hip. amphibius, to investigate size-shape relationship and to compare ontogenetic growth trajectories between both taxa. The study revealed that, during growth (increase in size and age), variations in skull shape are prominent in Hip. amphibius; juvenile and adult individuals of Hip. gorgops display strong morphological similarities but size and shape are poorly correlated. The results support the hypothesis that in a relatively early ontogenetic stage, Hip. gorgops was more specialized in its aquatic adaptation than Hip. amphibius.
A Review of Mucinous Cystic and Intraductal Neoplasms of the Pancreatobiliary Tract
Authors: Ozcan Kerem , Klimstra David S. 
Published: February 2022

Context.—
Although most pancreatic and bile duct neoplasms are solid, mucinous cystic neoplasms and intraductal neoplasms have been increasingly recognized even when clinically silent, thanks to the increased use of sensitive imaging techniques. Cystic and intraductal neoplasms of the pancreas are often resectable and curable and constitute about 5% of all pancreatic neoplasms. Owing to their preinvasive nature and different biology, recognition of these entities remains a major priority. Mucinous cystic neoplasms are histologically and clinically distinct from other cystic pancreatic neoplasms. Pancreatic intraductal neoplasms encompass 3 major entities: intraductal papillary mucinous neoplasm, intraductal oncocytic papillary neoplasm, and intraductal tubulopapillary neoplasm. Intraductal papillary neoplasms of bile ducts are also preinvasive mass-forming neoplasms with both similarities and differences with their pancreatic counterparts. All of these pancreatobiliary neoplasms have diverse and distinctive clinicopathologic, genetic, and prognostic variations.

Objective.—
To review the clinical, pathologic, and molecular features of mucinous cystic and intraductal neoplasms of the pancreatobiliary tract.

Data Sources.—
Literature review, diagnostic manuals, and guidelines.

Conclusions.—
This review will briefly describe well-known clinical and pathologic features and will focus on selected recently described aspects of morphology, grading, classification, and genomic alterations of cystic and intraductal neoplasms of the pancreatobiliary tract.
Musculoskeletal disorders increases the insomnia severity in nurses
Authors: Cici Remziye , Yilmazel Gülay 
Published: February 2022

Objectives To determine prevalence of musculoskeletal disorders and the relationship between insomnia severity among nurses working in a training and research hospital.
Material and Methods This descriptive study was carried out with 293 nurses. Cornell musculoskeletal disorders questionnaire for musculoskeletal disorders and insomnia severity index were used to determine the insomnia severity.
Results In our study, the severity of the discomfort was mostly moderate and mild in painful areas. There was a significant difference in terms of gender, educational status, marital status, seniority, types of working, and presence of chronic diseases for musculoskeletal disorders in different body regions (p<0.05). It was determined that the threshold level of insomnia was significantly higher in those with musculoskeletal disorders in other body regions except the knee and lower leg region (p<0.05).
Conclusion In our study, it was determined that musculoskeletal disorders were common in the upper body areas and the severity of insomnia was at the threshold level. Neck, right shoulder and right upper arm were risky body areas for insomnia.
Correlation of sleep quality and cardiac autonomic modulation in hemodialysis patients
Authors: Carneiro Erika Ribeiro , Azoubel Luana Anaisse , Dias Raimunda Carneiro , Dias Carlos José , Sá Emanuelle Sousa , Brito Dyego Araujo , Salgado Filho Natalino , Santos Elton Freitas , Rocco José Hermógenes , Mostarda Cristiano Teixeira , Bernardo Filho Mario 
Published: February 2022

Objectives Sleep disorders in patients on hemodialysis are frequent, but few studies correlate these disorders with autonomic dysfunction in these patients. This study aimed to verify whether clinical and laboratory variables and heart rate variability are associated with worse sleep quality verified by the Pittsburg subjective scale in patients on hemodialysis.
Material and Methods A cross-sectional study was performed on forty-eight patients. Epidemiological, clinical, and laboratory data were collected. After were performed by recording the heart rate variability and applied Pittsburg questionnaires, Beck anxiety index (BAI), and Beck depression index (BDI). The global PSQI score >5 indicates that a person is a poor sleeper, the patients were divided according to the scores in the Pittsburg questionnaire into good and poor sleepers and the differences between all variables were analyzed.
Results Forty-eight patients were evaluated and the prevalence of 68.7% (n=33) of poor sleep quality was verified. From the depression and anxiety questionnaires, it was found that only 18.7% (n=9) had criteria for depression. In the analysis of the sympathetic dysfunction parameters, it was found that in the group with good sleep quality in the frequency domain (HFm2) and the LFnu in the group with worse sleep quality. There was a positive correlation between sleep quality scores the anxiety and depression scores. It is also verified that the variables LFnu had a positive correlation with higher scores of quality of sleep and HFnu had a negative correlation with the highest scores of quality of sleep.
Conclusion In patients undergoing hemodialysis, the poorest quality of sleep is correlated with worse cardiac autonomic modulation as well as higher scores on the depression and anxiety scales.
Smartphone applications for sleep tracking: rating and perceptions about behavioral change among users
Authors: Karasneh Reema A. , Al-Azzam Sayer I. , Alzoubi Karem H. , Hawamdeh Sahar , Jarab Anan S. , Nusair Mohammad B. 
Published: February 2022

Introduction This study aims to assess existing sleep apps for mobile phones to determine the perceived effect of these applications on user’s attitudes, knowledge, willingness to change, and its likelihood to change behavior from a user’s perspective.
Material and Methods A systematic search was conducted through Google play store and iTunes Apple store using terms related to sleep tracking. Apps were evaluated using Mobile Application Rating Scale (MARS) tool for assessing and classifying mobile health applications quality. Additionally, a convenience sample of subjects were asked to evaluate the included apps for perceived sleep behavior changes.
Results The average MARS app quality score on a 5-point scale was 3.3. Between 30-50% of participants believed that sleep tracker apps are likely to increase awareness about sleep patterns and sleep hygiene, infuence sleep hygiene habits, and are likely to encourage help seeking for sleep hygiene when required.
Conclusion Apps available for sleep self-management and tracking may be valuable tools for self-management of sleep disorder and/or improving sleep quality, yet they require improvement in terms of quality and content, highlighting the need for further validity studies.
Criminal Law and Neuroscience: Theory and Practice in the Italian Perspective
Authors: Grandi Ciro 
Published: February 2022

The debate on the impact on criminal justice of the empirical evidence offered by techniques of brain exploration and behavioral genetics shows no sign of diminishing, fed by literature now boundless and by case law in constant growth. In the Italian system, the impact of neuroscience at trial is still rather limited and substantially confined to its sedes naturalis, that is to say, the insanity defense. Even in this area, however, there is a very cautious, if not sometimes distrustful, attitude on the part of the courts, still doubtful about the epistemological reliability of neuroscientific evidence. The interdisciplinary dialogue is called upon to help overcome uncertainties and resistance, to avoid the underestimation of data endowed – albeit in a complementary and integrative function – with an increasingly objective value.
Summary: 1. Foreword. - 2. Neuroscience: an outline. - Neuroscience and criminal law in the light of the radical-revolutionary model. - 4. Neuroscience and criminal law in the light of the moderate-compatibilist model. - 5. An overview of the use of “neuroscientific evidence” in practice - 6. Neuroscience and the evaluation of criminal capacity: a first assessment. - 7. The (still) limited impact of neuroscience in the Italian criminal trial. Diagnosis and prognosis. – 8. Conclusions.