bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using decision analysis to support implementation planning in research and practice
Authors: Smith Natalie Riva , Knocke Kathleen E. , Hassmiller Lich Kristen 
Published: July 2022

AbstractBackgroundThe process of implementing evidence-based interventions, programs, and policies is difficult and complex. Planning for implementation is critical and likely plays a key role in the long-term impact and sustainability of interventions in practice. However, implementation planning is also difficult. Implementors must choose what to implement and how best to implement it, and each choice has costs and consequences to consider. As a step towards supporting structured and organized implementation planning, we advocate for increased use of decision analysis.Main textWhen applied to implementation planning, decision analysis guides users to explicitly define the problem of interest, outline different plans (e.g., interventions/actions, implementation strategies, timelines), and assess the potential outcomes under each alternative in their context. We ground our discussion of decision analysis in the PROACTIVE framework, which guides teams through key steps in decision analyses. This framework includes three phases: (1) definition of the decision problems and overall objectives with purposeful stakeholder engagement, (2) identification and comparison of different alternatives, and (3) synthesis of information on each alternative, incorporating uncertainty. We present three examples to illustrate the breadth of relevant decision analysis approaches to implementation planning.ConclusionTo further the use of decision analysis for implementation planning, we suggest areas for future research and practice: embrace model thinking; build the business case for decision analysis; identify when, how, and for whom decision analysis is more or less useful; improve reporting and transparency of cost data; and increase collaborative opportunities and training.
Self-expressiveness and hedonic brand affect brand love through brand jealousy
Authors: Siddique Sehrash , Rajput Amer 
Published: July 2022

AbstractThis study investigates the effect of self-expressiveness and hedonic brand aspect on brand jealousy through brand love of female fashion clothing brands. Conceptualized research framework is empirically tested through utilization of Smart PLS. Data are collected through questionnaire survey from 313 female consumers of fashion clothing brand with convenience sampling. It is empirically proven that self-expressiveness and hedonic brand aspect are positively related with brand love and indirectly associated with brand jealousy for female fashion clothing brands. Brand love in association with brand jealousy enhances knowledge in the context of female fashion clothing brands.
Utilization of solid materials to remove ammonia from drinking water
Authors: Samy Reham , Abdelmonem Nabil , Ismail Ibrahim , Abdelghany Amr 
Published: July 2022

AbstractThe winter closure is an annual action taken every year by the Egyptian authorities by closing water flows in series of channels for maintenance of water channels where levels in water channels are forced to reduce. However, Kafr El Sheikh and El Behaira, located in North Egypt, were affected by pollutant during winter closure due to the drainage of industrial wastes causing high pollution load of ammonia (mainly) and other pollutants. This paper focuses on testing agricultural wastes and natural materials to decrease ammonia in water at the inlet of water treatment stations that may reach 30 mg/l which happened during the winter closure. Nine adsorbents were investigated for ammonia removal: sugarcane peels, activated diatom, activated carbon, activated zeolite, rice straw, white foam, ilmenite, red brick, and a mixture of ilmenite with sugarcane. The sugarcane peels were the optimum treatment solution with a removal efficiency of 58% at an initial concentration of 38 mg/l, ~ 0.7 g of the adsorbent mass, and pH ranges from 10 to 12 after 1 h of contact time. At the same time, ilmenite reached an efficiency of 62% at an initial concentration of 21 mg/l, ~ 1.7 g of ilmenite, and pH 7 after 1 h of contact time. In addition, the reaction kinetics and adsorption isotherms were investigated for the selected adsorbent sugarcane peels, and the results showed that it matched the first-order kinetics with a regression coefficient (R2) of 0.99 and Langmuir adsorption isotherm (R2) of 0.96.
Graphical Abstract
Subclinical Hypothyroidism and Sperm DNA Fragmentation: A Cross-sectional Study of 5401 Men Seeking Infertility Care
Authors: Zhao Shuhua , Tang Li , Fu Jingyun , Yang Zexing , Su Cunmei , Rao Meng 
Published: July 2022

Abstract

Context
Our previous study showed that paternal subclinical hypothyroidism (SCH) had a detrimental effect on the clinical outcomes of assisted reproductive technologies. However, it remains to be determined whether paternal SCH affects sperm DNA integrity.

Objective
To investigate the association between SCH and sperm DNA fragmentation in men seeking infertility care.

Methods
This cross-sectional study included 4983 men with euthyroidism and 418 men with SCH seeking infertility treatment in a tertiary care academic medical center between January 2017 and December 2021. The outcome measures were the absolute DNA fragmentation index (DFI) and the risk of abnormal DFI (defined as DFI ≥ 25% or ≥ 30%).

Results
The mean (SD) age of men with euthyroidism and men with SCH was 34.20 (5.97) and 35.35 (6.48) years, respectively (P &lt; 0.001). The difference in DFI was not statistically significant (adjusted mean: 19.7% vs 18.9% in the SCH and euthyroidism groups, respectively; P = 0.07) after confounder adjustment. A DFI ≥25% was significantly more frequent in men with SCH (20.57%) than in men with euthyroidism (14.49%) after confounder adjustment [odds ratio (OR) 1.43 (95% CI 1.09-1.88)]. DFI ≥ 30% was also significantly more common in men with SCH (11.72%) than in men with euthyroidism [6.74%; OR 1.84 (95% CI 1.34-2.52)]. In addition, thyroid-stimulating hormone concentration was significantly associated with an increased risk of having a DFI ≥25% (P &lt; 0.001) or ≥30% (P = 0.011).

Conclusion
SCH was significantly associated with an increased risk of an abnormal DFI.
Glucagon-like Peptide-1 Receptor-based Therapeutics for Metabolic Liver Disease
Authors: Yabut Julian M , Drucker Daniel J 
Published: July 2022

Abstract
Glucagon-like peptide-1 (GLP-1) controls islet hormone secretion, gut motility, and body weight, supporting development of GLP-1 receptor agonists (GLP-1RA) for the treatment of type 2 diabetes (T2D) and obesity. GLP-1RA exhibit a favorable safety profile and reduce the incidence of major adverse cardiovascular events in people with T2D. Considerable preclinical data, supported by the results of clinical trials, link therapy with GLP-RA to reduction of hepatic inflammation, steatosis, and fibrosis. Mechanistically, the actions of GLP-1 on the liver are primarily indirect, as hepatocytes, Kupffer cells, and stellate cells do not express the canonical GLP-1R. GLP-1RA reduce appetite and body weight, decrease postprandial lipoprotein secretion, and attenuate systemic and tissue inflammation, actions that may contribute to attenuation of metabolic-associated fatty liver disease (MAFLD). Here we discuss evolving concepts of GLP-1 action that improve liver health and highlight evidence that links sustained GLP-1R activation in distinct cell types to control of hepatic glucose and lipid metabolism, and reduction of experimental and clinical nonalcoholic steatohepatitis (NASH). The therapeutic potential of GLP-1RA alone, or in combination with peptide agonists, or new small molecule therapeutics is discussed in the context of potential efficacy and safety. Ongoing trials in people with obesity will further clarify the safety of GLP-1RA, and pivotal studies underway in people with NASH will define whether GLP-1–based medicines represent effective and safe therapies for people with MAFLD.
Case Control Study to Evaluate Tear Film Function and Ocular Surface Disorder in Diabetic Patients
Authors: Samreen Arif  , Jyoti Tulsani  , Sajid Naqvi  
Published: July 2022

BACKGROUND
Diabetic retinopathy and early development of cataracts are well-known ocular complications of long-standing diabetes. In recent years various researchers have reported ocular surface disorders, particularly dry eyes in diabetic patients which if left untreated may result in a variety of corneal complications. These ocular surface disorders can be clinically diagnosed by performing a detailed slit lamp examination, Schirmer's test and tear film break-up time. Our study intended at assessing tear film and ocular surface disorders in diabetic patients and study tear film function in them and compare it with non-diabetic patients.
METHODS
A comparative cross-sectional study was done on 100 diabetic and 100 non-diabetic patients > 30 years of age visiting OPD of health centre of tertiary care hospital of Central India. Clinical data and detailed clinical history were obtained from all subjects through direct patient interviews and reviewing of their medical records followed by a comprehensive ocular examination that included best-corrected vision, slit lamp examination, and Tear Film break up time (TBUT) & Schirmer test.
RESULTS
In our study, mean TBUT was found to be significantly reduced in diabetics (15.94 ± 3.8) as compared to non-diabetics (20.13 ± 6.6). No significant difference was found in the Schirmer test reading between diabetics (17.13 ± 3.20) and non-diabetics (19.20 ± 6.23). Diabetic male patients had significantly decreased mean TBUT & mean Schirmer test readings as compared to diabetic females. Mean Schirmer reading & Mean TBUT were lowest in a patients having > 20 years of DM and highest in patients having < 5 years of DM. No positive correlation was found between HbA1c (Glyosylated Haemoglobin) and diabetic retinopathy with TBUT/ Schirmer test readings.
CONCLUSIONS
Our study showed that the tear film stability was found to be affected in diabetic patients, as compared to non-diabetic subjects as evident by the lower level of TBUT in diabetic patients. Significantly reduced TBUT with no significant difference in Schirmer test reading in diabetic as compared to non-diabetic subjects might be due to a decrease in basal secretion with normal overall tear secretion. The absence of subjective symptoms of dryness in spite of decreased TBUT in the diabetic group might be due to a decrease in corneal sensitivity caused by diabetic peripheral neuropathy in diabetic patients. There was an increase in the prevalence of DES with an increasing duration of DM. Rheumatoid arthritis was found to be a risk factor for DES. Diabetic males were found to be at risk for developing dry eye syndrome. Hence it can be concluded from our study that every diabetic patient should undergo a comprehensive eye examination which should include various tests for dry eye assessing multiple tear parameters.
SEPA Based Flap for Covering Defect after Adult Exstrophy Epispadias Repair
Authors: Deepak Bolbandi  , Raghuveer  , Mayank Agarwal  
Published: July 2022

INTRODUCTION
Bladder exstrophy is a complex, rare disorder that affects the foetus in utero. Here the abdominal wall is not fully formed, leaving the pubic bones separated and the bladder exposed in the lower abdominal wall.
METHODOLOGY
Single-stage reconstructive and repair surgery was undertaken in adults diagnosed with bladder exstrophy epispadias complex. The superficial external pudendal artery flap was considered for covering the defect after extensive reviews and discussion.
CONCLUSION
An uneventful surgery with recovery and a two-year follow-up post-surgery did not account for any complications following the procedure. This shows that the superficial external pudendal artery flap can be considered a favourable option for urologists in the repair of bladder exstrophy epispadias complex when undertaken in a single sitting surgery, especially in adults.
MeSH Terms
Bladder Exstrophy, epispadias repair, superficial external pudendal artery, axial-pattern flap.
Motivasi Masyarakat Terhadap Aktivitas Car Free Day di Alun-alun Kabupaten Temanggung
Authors: FITRIANI RIZQI WITARI 
Published: July 2022

The purpose of this research to describe the community's motivation to sport activities In the Car Free Day Square of Temanggung district. The research method used Is a survey through a quantitative approach. Data collection Is done by observation, Interviews, and questionnaires. The results showed that the community's motivation to exercise due to physiological needs had a percentage of 23,3%, a safety requirement of 23,03%, a social need of 19.30%, the need for an award of 12,55%, and self-actualisation requirement of 21,49%. For the people of Temanggung distict,it is hoped that they can make as good as possible of Car Free Day activity because the Car Free Day is a means of self-actualization which is very beneficial for improving health, physical fitness, social and self-actualization. Then for the local government to expand the hygiene facilities such as trash cans and handwashing places and for organizers or community leaders still provide the best service so that the community Is Increasingly motivated to exercise In the Car Free Day of Temanggung District Square.
Manajemen Pembinaan Prestasi Klub Bola Voli Mitra Kencana Semarang Tahun 2021
Authors: Nailufar Nabila , Hartono Mugiyo 
Published: July 2022

Fokus kajian penelitian ini meliputi pengelolaan manajemen, pelaksanaan program pembinaan, atlet, pelatih, sarana, prasarana, dan prestasi. Tujuan peneliti untuk mengatahui manajemen pembinaan pada klub tersebut.
Peneliti menggunakan pendekatan deskriptif kualitatif. Pengumpulan data menggunakan metode observasi, wawancara, dokumentasi. Sumber data penelitian adalah pengurus, pelatih, dan atlet Klub Mitra Kencana Semarang. Subyek dalam penelitian adalah 1 pengurus, 3 pelatih, dan 8 atlet Klub Mitra Kencana Semarang.
Hasil penelitian ini adalah pengolahan manajemen dari berbagai aspek sudah sesuai dengan program kerja yang telah dibuat pada klub.
Simpulannya klub ini terstruktur dengan baik dan memiliki prestasi yang baik. Saran yang diberikan yaitu: 1) Pengurus dan pelatih perlu adanya penambahan anggota, 2) Lebih diperketat dalam kedisiplinan atlet agar lebih bertanggungjawab dalam mengikuti program latihan yang diberikan oleh pelatih, 3) Pendanaan senantiasa menjalin kerjasama dengan pihak-pihak luar, 4) Program latihan disesuaikan dengan kondisi eksternal atlet, 5) Melengkapi kekurangan sarana dan prasarana seperti gedung olahraga, 6) Perlu peningkatan prestasi agar sampai tingkat nasional.
Tingkat Penguasaan Materi PJOK dalam Proses Pembelajaran Secara Daring pada Siswa SD di Desa Jono Kecamatan Tawangharjo Kabupaten Grobogan 2021
Authors: Siwi Alif Haryo , Hartono Mugiyo 
Published: July 2022

Abstak
Penelitian ini menggunakan pendekatan kuantitatif dengan metode survei, teknik pengambilan sampelnya berupa total sampling berjumlah 71, pengumpulan datanya menggunakan angket. Analisis data menggunakan analisis SPSS berupa deskriptif statistik. Penelitian ini bertujuan untuk mendeskripsikan Tingkat pengetahuan materi penjasorkes Dalam Proses Pembelajaran Secara Daring Pada Siswa SD Di Desa Jono Kecamatan Tawangharjo Kabupaten Grobogan Tahun 2021. Hasil penelitian menunjukkan bahwa tingkat pengetahuan materi penjasorkes siswa Sekolah Dasar di desa Jono Kecamatan Tawangharjo Kabupaten Grobogan selama pembelajaran daring berada pada kategori “sangat tinggi” sebesar 0% ( 0 siswa), “tinggi” sebesar 38,03%( 27 siswa), “sedang” sebesar 22,54% (16 siswa), “rendah” sebesar 36,62%(26 siswa), “ sangat rendah” sebesar 2,82% (2 siswa). Kesimpulan adalah tingkat pengetahuan materi Penjasorkes siswa SD Di Desa Jono berada pada kategori “tinggi” dengan jumlah 27 siswa.
Abstract
This study uses a quantitative approach with a survey method, the sampling technique is a total sampling of 71, the data collection uses a questionnaire. Data analysis used SPSS analysis in the form of descriptive statistics. This study aims to describe the level of physical education material knowledge in the online learning process for elementary school students in Jono Village, Tawangharjo District, Grobogan Regency in 2021. The results showed that the level of physical education material knowledge of elementary school students in Jono Village, Tawangharjo District, Grobogan Regency during online learning was at category "very high" by 0% ( 0 students), "high" by 38.03% (27 students), "medium" by 22.54% (16 students), "low" by 36.62% (26 students ), “very low” by 2.82% (2 students). The conclusion is that the level of knowledge of physical education material for elementary school students in Jono Village is in the "high" category with a total of 27 students.
Dual Antiplatelet Therapy for 3 or 12 Months in Patients with Non-ST-elevation MI/Unstable Angina or ST-elevation MI: Analysis of the REDUCE Trial
Authors: Wan Ahmad Wan Azman , Benit Edouard , Legrand Victor M , Yahya Achmad Fauzi , Tan Huay Cheem , Rifqi Sodiqur , Abdul Kader Muhamad Ali SK , Pironi Bruno , de Winter Robert J , Tam Chor-Cheung Frankie , Ligtenberg Eric , De Luca Giuseppe , Suryapranata Harry 
Published: July 2022

Background: The aim of this subanalysis of the REDUCE (Short-term Dual Antiplatelet Therapy in Patients with ACS Treated with the COMBO Dual-therapy Stent) trial was to evaluate differences between non-ST-elevation MI/unstable angina (NSTEMI/UA) patients and ST-elevation MI (STEMI) patients in terms of patient characteristics, procedures and outcomes. Methods: In the REDUCE trial, 1,496 acute coronary syndrome patients undergoing successful COMBO stent implantation were randomised to 3 or 12 months of dual antiplatelet therapy (DAPT) treatment. In total, 789 (52.8%) patients had NSTEMI/UA and 706 (47.2%) had STEMI. For this analysis, NSTEMI/UA patients (n=789) were compared with STEMI patients (n=706). Results: In the analysis of the NSTEMI/UA and STEMI cohorts comparing 3-month DAPT (751 patients) and 12-month DAPT treatment (745 patients) there were no statistically significant differences in the primary endpoints of all-cause mortality, MI, stent thrombosis, stroke, target vessel revascularisation or bleeding (Bleeding Academic Research Consortium [BARC] II, III, V) at 360 and 720 days between the two cohorts. Comparing the overall primary endpoints in the NSTEMI/UA cohort, 3-month DAPT was better than 12-month DAPT (9.6% versus 10.0% at 360 days and 12.1% versus 15.0% at 720 days). In the STEMI cohort, 12-month DAPT was better than 3-month DAPT (8.4% versus 11.0% at 720 days). Conclusion: For NSTEMI/UA patients, a numerically lower occurrence of outcomes was observed with 3-month DAPT at 360 and 720 days, whereas for STEMI patients, 12-month DAPT appeared to be better at 720 days. NSTEMI patients seemed to have less favourable long-term outcomes than STEMI patients in this subanalysis. Further adequately powered randomised trials are needed to confirm the findings.
Edukasi Pengolahan Sampah Organik dan Anorganik di Desa Rejasa Tabanan
Authors: Nindya Ovitasari Ketut Sherly , Cantrika Dea , Murti Yolandari Ayu , Widana Erwin Satria , Kurniawan I Gede Agus 
Published: July 2022

Desa Rejasa Kabupaten Tabanan memiliki luas desa 2,44 km2. Desa Rejasa ini merupakan desa yang berkembang di bidang pertanian serta terdapat penangkaran ikan lele. Namun, ibu rumah tangga serta masyarakat Desa Rejasa belum mengetahui pemanfaatan pengolahan sampah organik dan anorganik, Oleh karena itu penting untuk menyadarkan kepedulian warga agar tidak sembarangan dalam membuang sampah serta mengedukasi terkait pengolahan sampah. Berawal dari permasalahan tersebut, kegiatan pengabdian kepada masyarakat (PkM) ini bertujuan memberikan solusi melalui edukasi pentingnya menjaga kebersihan desa, memilah sampah organik dan anorganik serta memanfaatkan olahan sampah tersebut sehingga memiliki nilai tambah. Bentuk nyata kegiatan ini berupa memberi fasilitas tempat sampah yang terpilah dan memberi pupuk kompos organik. Metode yang digunakan dalam kegiatan PkM ini adalah mengedukasi melalui tahapan sosialisasi, perijinan, persiapan,pelaksanaan dan evaluasi. Hasil dari kegiatan PkM yang dilaksanakan tanggal 20 Januari 2022 adalah pedulinya masyarakat terhadap pentingnya menjaga kebersihan, meningkatnya pemahaman masyarakat terhadap pemilahan sampah serta pengetahuan untuk memanfaatkan sampah. Selain itu masyarakat Desa Rejasa dapat mengetahui manfaat sampah dengan cara 3R Reduce, Reuse, and Recyle. Kegiatan PkM ini memberikan dampak positif karena hasil monitor dan evaluasi terbukti lingkungan menjadi bersih dan masyarakat telah berhasil mengolah sampah yang ada. Rejasa Village, Tabanan Regency, has a village area of 2.44 km2. Rejasa Village is a village developing in agriculture, and there is a catfish farm. However, homemakers and the people of Rejasa Village do not know about the use of organic and inorganic waste processing. Therefore, it is important to raise residents' awareness so that they are not careless in disposing of waste and educate them about waste management. Starting from these problems, this community service activity aims to provide solutions through education on the importance of maintaining village cleanliness, sorting organic and inorganic waste and utilizing processed waste so that it has added value. The tangible form of this activity is to provide facilities for segregated trash bins and provide organic compost. The method used in this community service activity is to educate through the stages of socialization, licensing, preparation, implementation and evaluation. The results of the service activities carried out on Thursday, January 20, 2022, showed the public's concern for maintaining cleanliness, increasing public understanding of waste sorting and knowledge of utilizing waste. In addition, the people of Rejasa Village can find out the benefits of waste through 3R Reduce, Reuse, Recycle. The implication is very positive because the monitoring and evaluation results prove that the environment is clean and the community has succeeded in processing the existing waste.