bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eksistensi Madrasah di Era Kontemporer Perspektif Ilmu Pendidikan Islam
Authors: Sari Yunita , Zaini Muhammad , Laili Nur 
Published: August 2022

This study intends to review the existence of madrasas in the contemporary era with the perspective of Islamic education. As an institution that has long developed in Indonesia, madrassas have succeeded in developing moral and religious values. In addition, madrasas also help instill a sense of nationality in the soul of the Indonesian people and participate in educating the nation. The existence of Madrasas as Islamic educational institutions is now placed as school education in the National Education System. The emergence of a three ministerial decree (Minister of Religion, Minister of Education and Culture, and Minister of Home Affairs) indicates that the existence of madrasas is strong enough along with public schools. In addition, the issuance of the three ministerial decree is also considered a positive step for improving the quality of madrasah in terms of status, diploma value and curriculum. The purpose of this research is to add and deepen insights about the existence of madrasas that are constantly developing and the factors that influence the existence of madrasas. The benefit of this research is as an effort to develop knowledge, abilities and skills. This type of research is a qualitative library (library research). This research uses qualitative methods with qualitative descriptive methods. The primary sources in this study are books on Islamic religious education and journals of madrasah urgency in the contemporary era. The result of this research is that currently madrasas have an equal position with general schools in the fields of graduates, diplomas, curriculum and job search. Madrassas are one of the educational institutions characterized by Islam that already exist in Indonesian society.
Keywords: Islamic Education, Developing Moral and Religious Study
Konsep Pendididkan Pemikiran Ki Ageng Suryomentaram dan Relevansinya Terhadap Pengembangan Agama
Authors: Yasin Ahmad , Suroya Lu‟luk 
Published: August 2022

This research aims to describe and analyze Ki Ageng Suryomentaram's thoughts regarding the concept of educators in the Kawruh Pamomong manuscript and its relevance to Islamic education. This research is a qualitative research with the type of library research (Library Research). In the process of collecting data using literary documentation method. The data analysis methods used in this study include data interpretation, descriptive analysis, synthesis analysis, and verification. The results of this study, namely, the concept of educators according to Ki Ageng Suryomentaram is that educators must have exemplary traits such as personal madeg pribadi (independent thinking), wasis (clever), kendel (brave), sregep (diligent), sugih (rich), sih (love), sepen ing pamrih (sincere), telaten (patient), Because indirectly students will imitate or imitate an educator. But in this case the author sees the concept of Ki Ageng Suryomentaram which is prioritized and the most basic is raos sih (love) that must be possessed by educators and instill it in students, so that a sense of happiness arises in seeking knowledge and obtaining beja (happiness) in his life. After being studied in depth, the concept of educators according to Ki Ageng SuryoMentaram does not contradict the al-Qur'an and al-Hadith.
Keywords: Ki Ageng Suryo Mentaram Thought, The Development Islamic Education
Ideal Teacher in the View of Az-Zarnuji and Al-Ghozali
Authors: Mahendra Benny Putra 
Published: August 2022

This paper was conducted by examining the books of Ta'limul Muta'aliim and Ihya 'Ulumuddin. The researcher discusses the ideal teacher according to Az-zarnuji and Al- Ghozali. Both were chosen because they have traditional educational thoughts but are still feasible to be applied today. The main purpose of this study is to determine the ideal teacher in view of both, determine the ideal teacher standard in modern learning and criticize the teacher's condition when teaching. The initial stage of this research collected library data and literature texts related to education, especially the ideal teacher according to Az-Zarnuji and Al-Ghozali. The second stage examines the Teacher in both views and examines the historiography of the writing of the two books. The method used is descriptive qualitative method. This method is used to present the ideal teacher in the views of Az- Zarnuji and Al-Ghozali and to criticize the teacher's condition when teaching. Specific targets in this study are 1) Ideal Teacher according to Az-Zarnuji and Al-Ghozali by studying the books of Ihya 'Ulumuddin and Ta'liimul Muta'alim. 2) Identifying the factors that influence their thinking in education 3) Identifying criticisms and providing solutions related to teacher conditions when teaching. The findings include low teacher competence, Al-Ghazali and Az-Zarnuji's thinking is influenced by Sufism and Worship, The criticism that appears is that teachers do not understand the role of educators, Teaching Motivation is influenced by internal and external factors in the teacher's personality.
Keywords: Az-Zarnuji, Al-Ghozalli, Ideal Teacher, Ta’limul Muta’aliim dan Ihya’ Ulumuddin.
Pembelajaran PAI di SMA: (Tujuan, Materi, Metode, dan Evaluasi)
Authors: Handayani Fitri , Ruswandi Uus , Arifin Bambang Samsul 
Published: August 2022

Islamic Religious Education is a conscious effort to guide students' personal orders in a systematic and pragmatic manner, volunteers live according to Islamic teachings, so as to realize the happiness of the hereafter PAI learning must be prepared by educators first, starting from planning to formulate goals, materials and methods to learning evaluation. This article aims to examine Islamic Education learning at SMA Al-Islam Bandung in terms of objectives, materials, methods, and evaluation. The method used in this study uses descriptive qualitative methods so that it can freely understand, analyze and describe the research data accurately. The results showed that the goal of learning Islamic Education at AL-Islam Senior High School is to be able to achieve core competencies and basic competencies in accordance with the material provided in improving intelligence, knowledge, personality, noble morals, and skills as a manifestation of achieving world happiness and the afterlife. includes PAI learning materials and the addition of BTQ and worship practices using the XXI century learning method through a scientific approach and using evaluation according to the provisions of the 2013 curriculum.
Kata Kunci: Islamic Education, Learning Islamic Education, Learning Classroom
Peran Guru dalam Menumbuhkan Kemampuan Literasi Siswa Kelas V di MIN 2 Baubau
Authors: Nudin Nudin 
Published: August 2022

Tujuan penelitian ini adalah: (1) Untuk mengetahui peran guru dalam menumbuhkan kemampuan literasi siswa kelas V dalam perencanaan pembelajaran di MIN 2 Baubau (2) Untuk mengetahui peran guru dalam menumbuhkan kemampuan literasi siswa kelas V dalam pelaksanaan pembelajaran di MIN 2 Baubau (3) Untuk mengetahui faktor penghambat dan pendukung dalam menumbuhkan kemampuan literasi siswa kelas V di MIN 2 Baubau. Penelitian ini merupakan penelitian kualitatif dengan menggunakan metode deskriptif analisis. Subjek dalam penelitian ini adalah kepala sekolah, serta guru kelas V MIN 2 Baubau. Pengumpulan data dilakukan dengan analisis RPP, observasi dan wawancara. Hasil simpulan dari observasi dan wawancara menunjukkan bahwa guru sudah menunjukkan perannya sebagai teladan, motivator, fasilitator dan kreator dalam menumbuhkan kemampuan literasi dasar siswa kelas V MIN 2 Baubau. Hambatan yang dialami oleh pihak sekolah dalam menumbuhkan kemampuan literasi dasar siswa adalah masih rendahnya minat siswa akan menumbuhkan budaya literasi. Adapun yang menjadi faktor pendukung dalam menumbuhkan kemampuan literasi siswa MIN 2 Baubau adalah adanya dukungan penuh dari pemerintah terhadap pelaksanaan Gerakan literasi sekolah.
Implementasi Pendidikan Agama Islam Pada Siswa SMP Kelas IX di Sekolah Alam Nurul Azkiah Baubau
Authors: Nudin Nudin 
Published: August 2022

Tujuan penelitian ini adalah untuk mendeskripsikan dan menganalisis implementasi, kendala, dan solusi dalam penerapan PAI di sekolah alam. Lokasi penelitian ini dilaksanakan di Sekolah Alam Nurul Azkiah Baubau.Metode penelitian yang digunakan dalam penelitian ini menggunakan pendekatan Kualitatif, dengan jenis penelitian lapangan (Field Research). Teknik pengumpulan data dilakukan dengan observasi, wawancara, dan dokumentasi. Uji keabsahan data dilakukan dengan triangulasi metode dan sumber. Teknik analisis data meliputi pengumpulan data, reduksi data, penyajian data dan penarikan kesimpulan.Hasil penelitian menunjukkan bahwasanya Sekolah Alam Nurul Azkiah Baubau Proses pembelajaran PAI di Sekolah Alam Nurul Azkiah Baubau tidak hanya dilakukan di dalam kelas (indoor) namun juga di luar kelas (outdoor), disesuaikan dengan materi yang disampaikan dan media yang akan digunakan. Proses pembelajaran di luar kelas menumbuhkan antusias yang tinggi bagi siswa, hal ini sebagaimana yang disaksikan oleh peneliti. Paling tidak ada beberapa aspek yang peneliti amati dikegiatan pembelajaran PAI di Sekolah Alam Nurul Azkiah Baubau yaitu aspek fiqih, aqidah, dan akhlak. Aspek fiqih terlihat dalam keadaan wudhu, shalat, dan jual beli, aspek aqidah terlihat dalam beriman kepada Allah, aspek akhlak terlihat dalam keseharian siswa dalam merawat tanaman, berprilaku jujur, menghormati yang lebih tua dan menjaga kebersihan. Hal ini dapat terlihat dari seluruh komponen yang ada saling mendukung.
Effects of replacing Brachiaria hay with either Desmodium intortum or dairy concentrate on animal performance and enteric methane emissions of low-yielding dairy cows
Authors: Korir Daniel , Eckard Richard , Goopy John , Arndt Claudia , Merbold Lutz , Marquardt Svenja 
Published: August 2022

In Africa, cattle are often fed low quality tropical roughages resulting in low-yielding animals with high methane (CH4) emission intensity (EI, g CH4/per unit of product). Supplementation with protein is known to improve the nutritive value of the otherwise low-quality diets. However, animal nutrition studies in East Africa that are accompanied by CH4 emission measurements are lacking. Thus, an animal experiment was conducted to quantify the effect of supplementing cattle fed mainly on low-quality Urochloa brizantha hay (control diet; CON; crude protein (CP) = 7.4%) or supplemented with either a tannin-rich leguminous fodder, Desmodium intortum hay (DES) or a commercial dairy concentrate (CUBES) on voluntary dry matter intake (DMI), nutrient apparent total tract digestibility, nitrogen (N) retention, enteric CH4 production and animal performance (milk and average daily gain). Twelve mid-lactating crossbred (Friesian × Boran) cows (initial liveweight = 335 kg) were used in a 3×3 (Period × Diet) Latin square design with each period running for four weeks. Compared to CON, DES decreased nutrient (DM, OM, CP) intake, apparent total tract digestibility and daily milk yield. In contrast, CUBES increased nutrient intake and animal performance compared to CON, while nutrients’ apparent total tract digestibility was not different, except for CP digestibility that increased. Compared to CON, DES and CUBES improved overall N retention by the animals as a proportion of N intake. The DES diet compared with CON and CUBES, shifted the proportion of N excretion via urine to the fecal route, likely because of its tannin content. Both DES and CUBES, compared to CON, reduced methane yield (MY, g CH4/kg DMI) by 15% and 9%, respectively. The DES diet reduced absolute enteric CH4 emissions by 26% while CUBES increased emissions by 11% compared to CON. Based on the present findings, high supplementation levels (&gt;50%) of Desmodium intortum hay is not recommended especially when the basal diet is low in CP content. Supplementation with lower levels of better managed Desmodium intortum forage however, need to be investigated to establish optimal inclusion levels that will improve animal productivity and reduce environmental impact of livestock in smallholder tropical contexts.
Agri-Nanotechnology and Tree Nanobionics: Augmentation in Crop Yield, Biosafety, and Biomass Accumulation
Authors: Abbas Manzar , Yan Kuan , Li Jia , Zafar Sara , Hasnain Zuhair , Aslam Nazia , Iqbal Naeem , Hussain Syed Sarfaraz , Usman Muhammad , Abbas Mubashir , Tahir Muhammad , Abbas Sammar , Abbas Saqi Kosar , Qiulan Huang , Zhao Xianming , El-Sappah Ahmed H. 
Published: August 2022

Nanomaterials (NMs) are the leading edge as an amazing class of materials that consists of at least one dimension in the range of 1–100 nm. NMs can be made with exceptional magnetic, electrical, and catalytic properties different from their bulk counterparts. We summarized unique features of NMs, their synthesis, and advances in agri-nanotechnology and cutting-edge nanobionics. The review describes advances in NMs including their applications, dosimetry to ensure biosafety, remote sensing of agro-forestry fields, nanofertilizers, and nanopesticides, and avoid post-harvest losses, gene delivery, and nanobionics. Tree nanobionics has enabled the synthesis and delivery of nanosensors, which enhance the rate of photosynthesis, detection of pathogens, and poisonous residues to ensure biosafety and biomass accumulation. Finally, we conclude by discussing challenges, future perspectives, and agro-ecological risks of using NMs.
Gold-based nanoparticles realize photothermal and photodynamic synergistic treatment of liver cancer and improve the anaerobic tumor microenvironment under near-infrared light
Authors: Li Bei , Fu Yi , Xie Maodi , Feng Lei , Niu Xiaoya , Que Lin , You Zhen 
Published: August 2022

In order to solve the different pains caused by traditional cancer treatment methods such as surgical treatment, the nano-drug delivery system provides new ideas for cancer treatment. In this paper, a novel anti-tumor therapy nanoparticle, P(AAm-co-AN)-AuNRs@CeO2-Ce6(PA/Ce6), is prepared, which provides a novel idea for liver cancer treatment. The CeO2-coated gold nanorods were grafted onto the surface of the temperature-sensitive polymer P(AAm-co-AN)-CTPD. The photosensitizer Ce6 is loaded on the surface of the nanoparticles and the polymer layer. CeO2 can effectively alleviate the tumor anaerobic microenvironment, and under 808 nm near-infrared (NIR) excitation, the gold nanorods achieve photothermal conversion to induce local heating, which leads to the phase transition of the polymer layer and realizes a controllable release mechanism. In addition, 660 nm NIR light can effectively induce Ce6 to produce singlet oxygen, thereby effectively killing cancer cells. Under the 808 nm laser irradiation within 600 s, the PA/Ce6 solution can heat up to about 60°C, which was enough to ablate both cancer cells and tumor tissues. When the temperature was 50°C, the cumulative release rate of Ce6 was 95.31%. Under the 808 nm laser irradiation, oxygen production capacity of PA/Ce6 was higher and can effectively reduce the content of hydrogen peroxide in cancer cells. Compared to free Ce6, the reactive oxygen species-mediated fluorescence of PA/Ce6 nanoparticles was greater. The cell viability and migration of HepG2 cells were decreased after the 660 and 880 nm lasers were irradiated at the same time. The cancer cells were further inhibited, showing a good in vitro anti-tumor effect. PA-DOX showed the best tumor growth inhibitory effect under NIR laser irradiation and had no acute toxicity in vivo. Due to the existence of AuNRs, nanoparticles had high-efficiency photothermal conversion ability to achieve photothermal therapy. Ce6 can generate singlet oxygen under the excitation of 660 nm laser to realize photodynamic therapy. The experimental results also showed that PA/Ce6 can effectively decompose hydrogen peroxide under laser irradiation, aiming to effectively alleviate the anaerobic microenvironment of tumors. These indicate that PA/Ce6 plays a promising role for hepatocellular carcinoma treatment.
Lumbar segment-dependent soft tissue artifacts of skin markers during in vivo weight-bearing forward–Backward bending
Authors: Xi Xin , Ling Zhi , Wang Cong , Gu Chunya , Zhan Xuqiang , Yu Haixin , Lu Siqi , Tsai Tsung-Yuan , Yu Yan , Cheng Liming 
Published: August 2022

Traditional optical motion capture (OMC) with retroreflective markers is commonly used to measure joint kinematics but was also reported with unavoidable soft tissue artifacts (STAs) when quantifying the motion of the spine. Additionally, the patterns of the STA on the lumbar spine remain unclear. This study aimed to 1) quantify the in vivo STAs of the human lower back in three-dimensional directions during weight-bearing forward–backward bending and 2) determine the effects of the STAs on the calculated flexion angles between the upper and lower lumbar spines and adjacent vertebrae by comparing the skin marker (SM)- and virtual bone marker (VM)-based measurements. Six healthy volunteers were imaged using a biplanar radiographic system, and thirteen skin markers were mounted on every volunteer’s lower back while performing weight-bearing forward–backward bending. The STAs in the anterior/posterior (AP), medial/lateral (ML), and proximal/distal (PD) directions were investigated. The flexion angles between the upper and lower lumbar segments and adjacent intervertebral segments (L2–L5) throughout the cycle were calculated. For all the participants, STAs continuously increased in the AP direction and exhibited a reciprocal trend in the PD direction. During flexion, the STA at the lower lumbar region (L4–L5: 13.5 ± 6.5 mm) was significantly higher than that at the upper lumbar (L1–L3: 4.0 ± 1.5 mm) in the PD direction (p &lt; 0.01). During extension, the lower lumbar (L4–L5: 2.7 ± 0.7 mm) exhibited significantly less STAs than that exhibited by the upper lumbar region (L1–L3: 6.1 ± 3.3 mm) (p &lt; 0.05). The STA at the spinous process was significantly lower than that on both sides in the AP direction (p &lt; 0.05). The present results on STAs, based on dual fluoroscopic measurements in healthy adult subjects, presented an anatomical direction, marker location, and anatomic segment dependency, which might help describe and quantify STAs for the lumbar spine kinematics and thus help develop location- and direction-specific weighting factors for use in global optimization algorithms aimed at minimizing the effects of STAs on the calculation of lumbar joint kinematics in the future.
Research on the osteogenesis and biosafety of ECM–Loaded 3D–Printed Gel/SA/58sBG scaffolds
Authors: Tan Guozhong , Chen Rongfeng , Tu Xinran , Guo Liyang , Guo Lvhua , Xu Jingyi , Zhang Chengfei , Zou Ting , Sun Shuyu , Jiang Qianzhou 
Published: August 2022

Employing scaffolds containing cell–derived extracellular matrix (ECM) as an alternative strategy for the regeneration of bone defects has shown prominent advantages. Here, gelatin (Gel), sodium alginate (SA) and 58s bioactive glass (58sBG) were incorporated into deionized water to form ink, which was further fabricated into composite scaffolds by the 3D printing technique. Then, rat aortic endothelial cells (RAOECs) or rat bone mesenchymal stem cells (RBMSCs) were seeded on the scaffolds. After decellularization, two kinds of ECM–loaded scaffolds (RAOECs–ECM scaffold and RBMSCs–ECM scaffold) were obtained. The morphological characteristics of the scaffolds were assessed meticulously by scanning electron microscopy (SEM). In addition, the effects of scaffolds on the proliferation, adhesion, and osteogenic and angiogenic differentiation of RBMSCs were evaluated by Calcein AM staining and reverse transcription polymerase chain reaction (RT–PCR). In vivo, full–thickness bone defects with a diameter of 5 mm were made in the mandibles of Sprague–Dawley (SD) rats to assess the bone regeneration ability and biosafety of the scaffolds at 4, 8 and 16 weeks. The osteogenic and angiogenic potential of the scaffolds were investigated by microcomputed tomography (Micro–CT) and histological analysis. The biosafety of the scaffolds was evaluated by blood biochemical indices and histological staining of the liver, kidney and cerebrum. The results showed that the ECM–loaded scaffolds were successfully prepared, exhibiting interconnected pores and a gel–like ECM distributed on their surfaces. Consistently, in vitro experiments demonstrated that the scaffolds displayed favourable cytocompatibility. In vitro osteogenic differentiation studies showed that scaffolds coated with ECM could significantly increase the expression of osteogenic and angiogenic genes. In addition, the results from mandibular defect repair in vivo revealed that the ECM–loaded scaffolds effectively promoted the healing of bone defects when compared to the pure scaffold. Overall, these findings demonstrate that both RAOECs–ECM scaffold and RBMSCs–ECM scaffold can greatly enhance bone formation with good biocompatibility and thus have potential for clinical application in bone regeneration.
Genome of the sea anemone Exaiptasia pallida and transcriptome profiles during tentacle regeneration
Authors: Shum Cheryl W.Y. , Nong Wenyan , So Wai Lok , Li Yiqian , Qu Zhe , Yip Ho Yin , Swale Thomas , Ang Put O. , Chan King Ming , Chan Ting Fung , Chu Ka Hou , Chui Apple P.Y. , Lau Kwok Fai , Ngai Sai Ming , Xu Fei , Hui Jerome H.L. 
Published: August 2022

Cnidarians including sea anemones, corals, hydra, and jellyfishes are a group of animals well known for their regeneration capacity. However, how non-coding RNAs such as microRNAs (also known as miRNAs) contribute to cnidarian tissue regeneration is poorly understood. Here, we sequenced and assembled the genome of the sea anemone Exaiptasia pallida collected in Hong Kong waters. The assembled genome size of E. pallida is 229.21 Mb with a scaffold N50 of 10.58 Mb and BUSCO completeness of 91.1%, representing a significantly improved genome assembly of this species. The organization of ANTP-class homeobox genes in this anthozoan further supported the previous findings in jellyfishes, where most of these genes are mainly located on three scaffolds. Tentacles of E. pallida were excised, and both mRNA and miRNA were sequenced at 9 time points (0 h, 6 h, 12 h, 18 h, 1 day, 2, 3, 6, and 8 days) from regenerating tentacles. In addition to the Wnt signaling pathway and homeobox genes that are shown to be likely involved in tissue regeneration as in other cnidarians, we have shown that GLWamide neuropeptides, and for the first time sesquiterpenoid pathway genes could potentially be involved in the late phase of cnidarian tissue regeneration. The established sea anemone model will be useful for further investigation of biology and evolution in, and the effect of climate change on this important group of animals.
Are all antibiotic persisters created equal?
Authors: Shultis Michael W. , Mulholland Claire V. , Berney Michael 
Published: August 2022

Antibiotic persisters are a sub-population of bacteria able to survive in the presence of bactericidal antibiotic despite the lack of heritable drug resistance mechanisms. This phenomenon exists across many bacterial species and is observed for many different antibiotics. Though these bacteria are often described as “multidrug persisters” very few experiments have been carried out to determine the homogeneity of a persister population to different drugs. Further, there is much debate in the field as to the origins of a persister cell. Is it formed spontaneously? Does it form in response to stress? These questions are particularly pressing in the field of Mycobacterium tuberculosis, where persisters may play a crucial role in the required length of treatment and the development of multidrug resistant organisms. Here we aim to interpret the known mechanisms of antibiotic persistence and how they may relate to improving treatments for M. tuberculosis, exposing the gaps in knowledge that prevent us from answering the question: Are all antibiotic persisters created equal?