bluuebunny/crossref_metadata_2025_split huggingface dataset:
Duidelijkheid over de rol van de advocaat als onderzoeker
Authors: Biemond H.J.Th. , Lopik S.J. 
Published: August 2022

Duidelijkheid over de rol van de advocaat als onderzoeker. Annotatie bij Raad van Discipline Amsterdam 25 juli 2022, ECLI:NL:TADRAMS:2022:140
De Raad van Discipline heeft een uitspraak gewezen over de rol van de advocaat als feitenonderzoeker. De tuchtrechter erkent daarin de plaats van feitenonderzoek door advocaten, maar stelt hieraan voor bepaalde onderzoeken terechte grenzen. In het geval van een rapport door een onafhankelijk advocaat-onderzoeker dat extern wordt gebruikt gelden er namelijk ‘zware eisen’, aldus de tuchtrechter. De uitspraak laat ook enkele bestaande vragen onbeantwoord en roept nieuwe vragen op. Deze annotatie bespreekt enkele van die vragen.
Impact of Antiphospholipid Antibodies on Intracytoplasmic Sperm Injection Outcome
Authors: Hareth Ismail Mohamed  , Wael Abdellatif Khafagy  , Mahmoud Salah Mahmoud  , Mahmoud Farouk Midan  
Published: August 2022

Introduction and Aim: The effect of antiphospholipid syndrome on pregnancy is extensively discussed but the debate is still ongoing. This debate increased when the association was examined after assisted reproductive techniques for infertility. The current work aimed to evaluate the influence of Antiphospholipid antibodies in patient undergo first cycle of intracytoplasmic sperm injection.
Subjects and Methods: The study comprised 130 of infertile females, who were scheduled for the first ICSI cycle. Before protocol selection, basal hormonal assay was performed and included FSH, LH, E2, prolactin and AMH. Plasma concentration of anti-phospholipids (APAs) was measured. Then, females were categorized into groups according to APAs (positive and negative groups). After ICSI, the clinical pregnancy was confirmed by presence the gestational sac or sac with positive pulsation. Ongoing pregnancy was recognized if the pregnancy continued after 12 weeks of the gestation and clinical miscarriage if pregnancy terminated before 12 weeks of gestation.
Results: All females were in their reproductive age (18- 40 years). Their fertility duration ranged between 1 and 7 years, and it was of primary type among 96 women. The long agonist protocol was used for 72 women and the antagonist protocol done for 58 women. The Antiphospholipid antibodies were positive among 27 females (20.8%), and there was no significant difference between APL positive and negative groups regarding pregnancy results (either chemical, clinical, incidence of abortion or ongoing pregnancy after 12 weeks) for all females. However, in women with positive clinical pregnancy, the rate of abortion was significantly increased in patients with APL- positive than negative females (66.7% vs 26.7%).
Conclusion: The presence of APA was associated with higher significant abortion rate after the first cycle of ICSI. Thus, screening for APA in women with infertility scheduled for assisted reproduction is recommended.
Light-Dependent Reactions of Photosynthesis in Mesophyll and Bundle Sheath Chloroplasts of C4 Plant Maize. How Our Views Have Changed in Recent Years
Authors: Romanowska Elżbieta , Wasilewska-Dębowska Wioleta 
Published: August 2022

Abstract
Plants experience a range of light intensities and qualities in their environment. Leaves are subjected to spatial and temporal gradients in incident light, which has major consequences in the photosynthetic carbon assimilation. Plants acclimate to light by developing a range of mechanisms, from adjustments in leaf morphology to changes in the photosynthetic apparatus stoichiometry. In C4 plants, light intensity is a major limiting factor for photosynthesis at optimum temperatures. Under limiting light, it is not clear if all of factors (e.g., temperature, mineral nutrition, water supply) are co-limiting or if there is one primary limitation. Differences in light quality and intensity have a profound impact on C4 photosynthesis, where pathways require metabolic coordination of the mesophyll and bundle sheath cycles. Changes in the linear versus cyclic electron flux in maize (NADP-malic enzyme C4 subtype) in the mesophyll and bundle sheath chloroplasts in response to light may lead to an imbalance in the coordination of the C3 and C4 pathways. Additionally, the rearrangement of the thylakoid complexes of both types of chloroplasts in maize optimizes the light energy distribution between the mesophyll and bundle sheath cells and may also participate in energy dissipation. This review aims to highlight the changes in the understanding of the functions of photosystem II in maize bundle sheath chloroplasts and the role of super and megacomplexes in the thylakoids.
Impactos da pandemia de COVID-19 na saúde mental dos profissionais de saúde do Brasil: uma revisão integrativa.
Authors: Felipe Ismael , Kiara de Beserra de Oliveira Thárcia 
Published: August 2022

Introdução: A pandemia de Covid-19 trouxe à tona inseguranças, adversidades e medos que há décadas a comunidade internacional não experienciou. Pandemias implicam em mudanças bruscas no cotidiano da sociedade. Essas implicações geram impactos que podem ultrapassar a capacidade de enfrentamento das pessoas que a vivenciam. Nesse contexto, o presente artigo visou revisar integrativamente os possíveis impactos psicológicos decorrentes dessa realidade. Objetivo: Realiza de maneira integrativa uma revisão demonstrando os impactos da pandemia de covid-19 na saúde mental dos profissionais de saúde brasileiros. Métodos: Trata-se de uma revisão integrativa, na qual foram analisados estudos publicados em língua inglesa e portuguesa, entre 1 de janeiro de 2020 a 10 de fevereiro de 2021, tendo como referência a base de dados SCIELO (Scientific Electronic Library Online) e PUBMED (Public Medline or Publisher Medline) empregando os seguintes descritores: Mental Health, Covid-19, Health Workers, Brazil. Resultados: Dos 39 estudos identificados após a remoção das duplicatas, 12 preencheram os critérios de elegibilidade. Conclusões: Existe uma notória associação entre a pandemia de COVID-19 e o agravo da saúde mental dos profissionais de Saúde do Brasil. No futuro, poderá haver uma alta demanda nos serviços de atenção psicológica devido às consequências dos impactos da Pandemia na saúde mental da população estudada, fato que torna necessário a realização de pesquisas e de estratégias para reverter essa adversidade.
UPAYA MEMBANGUN DAN MEMELIHARA SEMANGAT BELAJAR DI MASA PANDEMI PADA YAYASAN PONDOK PESANTREN IZZATUL ISLAM
Authors: Asep Suherman  , Yusuf Yusuf , Budi Ismanto  , Danang Choirul Umam  
Published: August 2022

Pengabdian pada masyarakat sebagai salah satu tri darma perguruaan tinggi menepati posisi yang strategis dalam menimba dan mendidik masyarakat untuk meningkatkan kualitas hidup masyarakat. Adapun wujud pembinaan tersebut diantaranya melalui pelatihan keterampilan dan pendampingan yang dianggap berguna bagi khalayak masyarakat setempat. Program kreativitas mahasiswa untuk melaksanakan darma perguruan tinggi yang ketiga yaitu pengabdian pada masyarakat. Pengabdian Kepada Masyarakat (PKM) dengan tema Upaya Membangun dan Memelihara Semangat Belajar Di Masa Pandemi Pada Yayasan pondok pesantren Izzatul Islam, Bentuk dari program ini adalah sosialisasi kepada para pelajar, agar tetap aktif trampil dan cerdas saat pandemi. Semangat belajar dapat dimiliki dengan meningkatkan motivasi belajar. Motivasi belajar adalah sebuah penggerak atau pendorong yang membuat seseorang akan tertarik kepada belajar sehingga akan belajar secara terusmenerus. Motivasi yang rendah dapat menyebabkan rendahnya keberhasilan dalam belajar sehingga akan merendahkan prestasi belajar siswa.
Pengaruh Pengetahuan, Religiusitas dan Kepercayaan Terhadap Minat Menabung di Bank Syariah
Authors: Rudi Haryono  
Published: August 2022

Abstrak
Penelitian ini bertujuan untuk melihat pengaruh faktor Pengetahuan, Religiusitas dan Kepercayaan terhadap minat menabung di Perbankan Syariah pada masyarakat Kota Jambi. Sampel dalam penelitian ini difokuskan pada masyarakat kota Jambi yang menjadi nasabah bank syariah yang berjumlah 100 orang. Analisis yang digunakan adalah analisis regresi linier berganda dengan bantuan SPSS. Berdasarkan penelitian ini, masyarakat tertarik untuk menabung karena sudah mengetahui tentang bank syariah baik dari akadnya, perbedaannya dengan bank konvensional maupun pengetahuan lainnya tentang bank syariah. Pengujian secara simultan ketika variabel Pengetahuan, religiusitas dan kepercayaan diuji secara bersama-sama memiliki pengaruh yang signifikan terhadap minat masyarakat Kota Jambi untuk menabung di bank syariah. Ketiga variabel tersebut memiliki pengaruh sebesar 57,4% terhadap minat masyarakat Kota Jambi untuk menabung di bank syariah. Sisa 42,6% minat menabung masyarakat Kota Jambi terhadap bank syariah dipengaruhi oleh faktor lain yang tidak diteliti dalam penelitian ini.
Kata Kunci: Pengetahuan, Religiusitas, Kepercayaan dan Bank Syariah.
USMLE attempts and impact on IMG to get into residency match
Authors: Juburi Israa 
Published: August 2022

According to many experts, USMLE exams are the most difficult exams that a medical students will ever take and it is the exam that managed by the National Board of Medical Examiners (NBME).
To be licensed to practice medicine in the United States, all medical students should pass all steps of the USMLE. IMGs form 25% of all the healthcare providers in the United States. Many Facts indicate that some IMGs provide better patient outcomes than US practitioners.
Many of IMGs or even US medical graduates have USMLE attempts. These attempts will affect their residency application and chances to get interviews which most of IMGs are concerned about it.
It is important for the IMG applicants who are having multiple attempts to know that it is not the end of medical residency match and there is no direct filter for USMLE attempts instead it’s a programs preference.
This article discusses important tips to overcome USMLE attempts and improve their chances of securing an interview and subsequent match.
Alago Proverbs as Vehicle of Values and Virtues
Authors: Ose Agbo Chika 
Published: August 2022

Scholars working on proverbs from major ethnic stocks in Nigeria have observed that this unique verbal art functions in many ways as a validator of a people’s culture, a tool for rhetoric, education and socialisation, and as a measure of a person’s cognitive ability. In all these, little or nothing has been done on the value of proverbs from minority cultures with a view to determining the bearing of echoes for possible reorientation for the individual and building of a positive collective consciousness in a postcolonial polity as Nigeria’s. This paper therefore focuses on one of Nigeria’s minority peoples and cultures: the Alago and their proverb lore. It examines the relevance of proverbs from the functionalist perspective as the embodiment of a people's beliefs, values, taboos and expectations, even as these bear echoes necessary for social stability. Drawing from the Alago society, this paper observes that proverbs, entrenched in traditional thoughts, have the potentials for serving as significant mines for enlarging on positive individual virtues and the polity’s values.
Germplasm Evaluation, Genetic Variability, Heritability, Genetic Advance, and Character Analysis in Scented and Non-Scented Rice (Oryza sativa L.) Under Irrigated Conditions
Authors: Pathak Satyam , Tiwari Manoj , Sharma Priya , Dwivedi Abhishek , Vimal Subhash Chandra , Debnath Ashim , Tripathi Shiva 
Published: August 2022

Eighty-nine germplasm of rice (Oryza sativa L.) along with four checks were evaluated in a well-prepared field to assess the genetic variability, heritability, and genetic advance for different characters under irrigated conditions in Augmented Block Design. In this study, the analysis of variance revealed highly significant or significant for all the 13 characters except non–significant for 1000- grain weight. High and moderate broad sense heritability was recorded for all the characters except 1000-grain weight, days to maturity, days to 50 % flowering, and spikelet fertility which showed low heritability. Genetic advance in percent of mean recorded high and moderate for all the characters except 1000-grain weight, days to 50 % flowering, number of fertile spikelet per panicle, and spikelet fertility which had the low genetic advance. The phenotypic and genotypic coefficient of variation was recorded higher for flag leaf area and moderate for harvest index, days to maturity, and L/B ratio. Non- hierarchical Euclidean analysis grouped the eighty-nine germplasm into eight clusters and this study showed the existence of wide genetic diversity within Oryza sativa germplasm. Among the eight clusters, the highest number of genotypes were present in cluster III which contained 23 entries, followed by cluster IV and cluster VII with 14 and 11entries, respectively. While least no genotypes were present in cluster VIII contained only 4 genotypes. The highest intra-cluster distance was observed in cluster II (3.664) while the lowest was in cluster V (2.327). In the case of inter-cluster distance, the highest value was observed between cluster VIII and cluster II (5.698) while the lowest value was observed between V and III clusters (2.808). The genotypes present in the diverse clusters may serve as parental material for the hybridization program which will lead to the isolation of desirable sergeants for developing high-yielding rice varieties under irrigated conditions.
Trade Competitiveness of Jute in India: Environmental Aspects
Authors: P. Baviskar Paresh , S. Perke D. , V. Chavan R. , G. Kadu A. , P. Gaware U. 
Published: August 2022

The study was aimed to investigate the comparative advantage and competitiveness of Indian jute. The study was based on secondary data for the period of 30 years (1989-90 to 2018-19). The collected data were sub-divided into three periods and Export Performance Ratio (EPR) was used to measure the comparative advantage of Indian jute. The global competitiveness of jute was evaluated using Nominal protection Coefficient (NPC). The results showed that, the Indian jute had a comparative advantage during all the periods of the study. During all the sub-periods viz, period I, period II and period III and overall period almost all the years, jute export registered the EPR/RCA values greater than unity indicated that India had considerable potential in jute export. The positive RSCA from period I to period III could be attributed to increase in the exports due to increase in jute productivity with the introduction of quality seeds of jute. Jute was found to be moderately competitive as NPC during overall period, was less than unity also, the period-wise NPC values showed that, Indian jute was moderately competitive during period I and period III. While, period II had a non-competitive market with NPC value of 1.39 which might be due to the reduction in area under jute in the country and increasing demand that led to increase in the domestic price of jute during the years under period II. Hence, it is suggested that the efforts are needed to address the constraints in cultivation and efforts are needed to increase productivity through advanced technologies. Development of market infrastructure, storage and transport will increase export. In order to face competition and increase India’s market share in world market India need to consistently supply high quality jute at competitive prices.
Multicentre Evaluation of Type 2 Diabetes Mellitus Outpatients on Insulin Therapy in Nigeria (METOIN Study)
Authors: O. Nkpozi M. , M. Ezeude C. , A. Owolabi F. , Bozimo G. E. , U. Ogbonna S. , Akhidue K. 
Published: August 2022

Background: Insulin use in type 2 diabetes mellitus (T2DM) outpatients remains largely not well accepted in Nigeria. Both the physicians and the patients thread with caution whenever insulin is suggested as an outpatient treatment option. This study, therefore, is on the type 2 diabetes mellitus outpatients on insulin therapy despite the misgivings against insulin.
Methodology: This was a cross sectional study in which consenting T2DM outpatients who meet the inclusion criteria for the study in five tertiary health facilities were recruited and relevant data obtained via investigator-administered questionnaire between January 1, 2020 and December 31, 2021. Data obtained were analyzed using Statistical Package for Social Sciences (SPSS) version 23.0 software.
Results: A total of 268 T2DM outpatients were recruited into the study, made up of 116 (43.3%) men and 152 (56.7%) women. Out of this, 212 (79.1%) patients did not start insulin from onset of the illness. Insulin initiation was done for 203 (75.7%) of the patients by endocrinologists in teaching and specialist hospitals. A total of 161 (69.1%) patients used insulin pen. Insulin was self-administered by 189 (70.5%) of the patients while intermediate acting insulin was the predominant insulin used by 127 (47.4%) of the patients. No insulin side effect was reported by 191 (71.3%) of the patients and 252 (94.0%) patients reported that insulin injection pain was not enough reason not to be on insulin. Of the total number of patients, 110 (41.0%) patients reported hypoglycaemia which was treated at home by 90 (81.8%) of the patients. A total of 225 (84%) patients had personal glucometers of which 182 (80.9%) patients had glucose strips at the time of being recruited into the study.
Conclusion / Recommendation: This study has shown that insulin is initiated for majority of patients several years after the onset of the illness and that insulin is initiated mainly at teaching and specialist hospitals. Insulin pens were predominantly used and most of the patients self administered insulin which had no side effects in majority of them. Self glucose monitoring of blood glucose was done by a majority of the patient. It is recommended that continuous diabetes education and improvement in insulin technology be done to increase insulin acceptance and usage.
Learning by explaining after pauses in video lectures: Are provided visuals a scaffold or a crutch?
Authors: Fiorella Logan 
Published: August 2022

AbstractExplaining after pauses in a video lecture can be an effective learning activity, yet students need support to generate comprehensive explanations. This study tested whether providing students access to the visualizations from the video enhances explanation comprehensiveness and transfer performance. Undergraduates (n = 112) watched a 5‐part lesson on the human kidney consisting of explanations and drawings. After each part, students typed an explanation without access to information from the video (explain group) or with access to the visualizations from the video (explain‐visuals group), or they studied the visualizations and transcript from the video (restudy group). Students who explained significantly outperformed the restudy group on the transfer test (d = .47). The explain‐visuals group generated significantly more comprehensive explanations during learning than the explain group (d = .54), but this did not result in significantly better performance on the subsequent transfer test (d = .09), suggesting the visuals may have served as a crutch more than a scaffold.
Hydroxychloroquine and Risk of Long QT Syndrome in Rheumatoid Arthritis: A Veterans Cohort Study With Nineteen‐Year Follow‐up
Authors: Quiñones Mercedes E. , Joseph Joyce K. , Dowell Sharon , Moore Hans J. , Karasik Pamela E. , Fonarow Gregg C. , Fletcher Ross D. , Cheng Yan , Zeng‐Treitler Qing , Arundel Cherinne , Liappis Angelike P. , Sheriff Helen M. , Zhang Sijian , Taub Daniel D. , Heimall Michael S. , Faselis Charles , Kerr Gail S. , Ahmed Ali 
Published: August 2022

ObjectiveRecent evidence suggests that hydroxychloroquine use is not associated with higher 1‐year risk of long QT syndrome (LQTS) in patients with rheumatoid arthritis (RA). Less is known about its long‐term risk, the examination of which was the objective of this study.MethodsWe conducted a propensity score–matched active‐comparator safety study of hydroxychloroquine in 8,852 veterans (mean age 64 ± 12 years, 14% women, 28% Black) with newly diagnosed RA. A total of 4,426 patients started on hydroxychloroquine and 4,426 started on another nonbiologic disease‐modifying antirheumatic drug (DMARD) and were balanced on 87 baseline characteristics. The primary outcome was LQTS during 19‐year follow‐up through December 31, 2019.ResultsIncident LQTS occurred in 4 (0.09%) and 5 (0.11%) patients in the hydroxychloroquine and other DMARD groups, respectively, during the first 2 years. Respective 5‐year incidences were 17 (0.38%) and 6 (0.14%), representing 11 additional LQTS events in the hydroxychloroquine group (number needed to harm 403; [95% confidence interval (95% CI)], 217–1,740) and a 181% greater relative risk (95% CI 11%–613%; P = 0.030). Although overall 10‐year risk remained significant (hazard ratio 2.17; 95% CI 1.13–4.18), only 5 extra LQTS occurred in hydroxychloroquine group over the next 5 years (years 6–10) and 1 over the next 9 years (years 11–19). There was no association with arrhythmia‐related hospitalization or all‐cause mortality.ConclusionsHydroxychloroquine use had no association with LQTS during the first 2 years after initiation of therapy. There was a higher risk thereafter that became significant after 5 years of therapy. However, the 5‐year absolute risk was very low, and the absolute risk difference was even lower. Both risks attenuated during longer follow‐up. These findings provide evidence for long‐term safety of hydroxychloroquine in patients with RA.
Update on the Efficacy and Safety Profile of Voclosporin: An Integrated Analysis of Clinical Trials in Lupus Nephritis
Authors: Arriens Cristina , Teng Y. K. Onno , Ginzler Ellen M. , Parikh Samir V. , Askanase Anca D. , Saxena Amit , Gibson Keisha , Caster Dawn J. , Atsumi Tatsuya , Lisk Laura , Randhawa Simrat , Gluck Rashieda , Solomons Neil , Huizinga Robert B. 
Published: August 2022

ObjectiveThis integrated analysis evaluates the efficacy and safety of voclosporin, a novel calcineurin inhibitor, at 23.7 mg twice daily in combination with mycophenolate mofetil (MMF) and oral glucocorticoids in lupus nephritis (LN) using pooled data from two large phase II and phase III clinical trials. The purpose was to expand the pool of patients for safety analyses and to increase power for efficacy analyses in patient subpopulations.MethodsAurinia Urinary Protein Reduction in Active Lupus with Voclosporin (AURA‐LV) (phase II) and Aurinia Renal Response in Active Lupus With Voclosporin (AURORA 1) (phase III) were randomized, placebo‐controlled, double‐blind trials with similar designs and end points comparing voclosporin to control in combination with MMF and oral glucocorticoids for the treatment of LN. The primary efficacy outcome of the integrated analysis was complete renal response (CRR) at approximately one year (Week 48 data from AURA‐LV and Week 52 from AURORA 1). Safety was assessed throughout the trials.ResultsOverall, 534 patients (268 voclosporin; 266 control) were included in the integrated analysis. Significantly more patients achieved a CRR at one year in the voclosporin group than in the control group (43.7% vs. 23.3%; OR 2.76; 95% CI 1.88, 4.05P< 0.0001). The incidence of adverse events (AEs) was similar (91.4% voclosporin; 87.2% control). Most AEs were mild to moderate in severity; the most commonly reported AEs were classified as infections and infestations (62.2% voclosporin; 54.9% control) and gastrointestinal disorders (45.3% voclosporin; 35.3% placebo). No new or unexpected safety signals were detected.ConclusionsThis integrated analysis demonstrates the efficacy and safety of voclosporin in the treatment of LN across the diverse racial and ethnic groups studied.