bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ordoliberalism within the Historical Trajectory of Neoliberalism
Authors: Mirowski Philip 
Published: October 2022

Abstract
Thomas Biebricher (2017) has asked: What does it mean to say that Ordoliberalism was a variety of Neoliberalism? I attempt to answer this question by providing a very brief account of ‘schools of thought’ within the Mont Pelerin Society 1947–1980, and then describing the roles and functions performed by Ordoliberals within that context. My general thesis is that Ordoliberalism was central to the earliest attempts to construct neoliberal doctrine, but became sidelined by the 1980s due to very specific intellectual developments and personnel changes. Roughly, one would observe the torch being passed, initiating with the Ordoliberals, then to the Hayekians, and subsequently to the Chicago School. Hence, we observe that the quest for a single ‘ideal-type’ representative of neoliberal thought would be fated to disappointment, absent something like an historical understanding of its trajectory.
On Learning and Teaching for Conceptual Change
Authors: Lombardi Doug , Danielson Robert W. 
Published: October 2022

Abstract
Many people have conceptions about the natural or anthropogenic world that may be inconsistent with domain knowledge. These lay conceptions, often called misconceptions, may be robust to change, thus requiring special considerations for learning and teaching (i.e., requiring conceptual change). In this article, the authors highlight the nature of concepts and learning via conceptual change as theorized and empirically studied over the last several decades. The authors also feature four popular and/or promising instructional modes for facilitating conceptual change, including scaffolded approaches to cognitive dissonance, refutation, argumentation, and modeling, which hold promise in promoting deeper understanding of our world and society.
Analyses of historical solar eclipse records in Hokkaido Island in the 18–19th centuries
Authors: Hayakawa Hisashi , Sôma Mitsuru , Daigo Ryuma 
Published: October 2022

Abstract
Solar eclipses have been recorded throughout history and across various ethnic groups. Their records have benefitted scientific discussions on multiple topics. These astronomical spectacles have also been recorded in the Japanese archipelago, but little has been known of the historical observations in the northern end: Hokkaido Island (known as Ezo Island until 1869). Here, we analysed three such early eclipse accounts from Hokkaido Island, both philologically and astronomically. We first analysed Tokunai Mogami's eclipse account written in 1786 January, which has been associated with the earliest eclipse record in Hokkaido Island. Our analysis showed that this eclipse was a deep partial solar eclipse outside the annular totality path of a hybrid eclipse, whereas it had previously been associated with an annular solar eclipse. This eclipse was also witnessed in the Ryukyu Kingdom, probably as a deep partial eclipse. We also located eclipse sketches in Kan’ichiro Mozume's diary and confirmed the local visibility of the annular eclipse in Otaru in 1872 June. We further analysed John Batchelor's eclipse folklore and identified the reported eclipse with a total solar eclipse in 1824 June. This folklore reported “tongues of fire and lightning” from the side of the “black dead sun.” This description is morphologically consistent with that of solar coronal streamers around the solar minima. This eclipse is chronologically located around the minimum of Solar Cycles 6/7 and contrasts the Dalton Minimum with the Maunder Minimum, for which coronal streamers were reportedly missing, according to visual observations.
Fiction and Disinformation in Early Modern Europe: An Introduction
Authors: Claussen Emma , Zenobi Luca 
Published: October 2022

Abstract
This chapter introduces the reader to the world of fiction and disinformation in early modern Europe. It starts by placing fiction and disinformation in the context of wider trends and developments, while also drawing a parallel between present practices and concerns and those of the early modern period (Section I). The chapter then surveys existing scholarship on these themes, highlighting the novelty of recent research and the transformative potential of interdisciplinary work (Section II). Finally, it sets out the approach and methodology which underpin the rest of volume (Section III). It is argued that fiction and disinformation need to be studied in tandem, and that their study should be guided by a combination of literary and historical approaches. This method is exemplified by the volume’s nine chapters. They all conduct close readings of falsehoods and fictional writings, examining their rhetorical and linguistic qualities, including matters such as style, narrative and genre; and they also uncover how fiction and disinformation brought about change in society and in the lives of the people who wrote them as much as those who read them. This makes the Supplement as a whole a methodological intervention, further bridging the gap between historical analysis and cultural criticism, and a contribution to the social and cultural history of early modernity.
The trajectory in catalytic evolution of Rubisco inPosidoniaseagrass species differs from terrestrial plants
Authors: Capó-Bauçà Sebastià , Whitney Spencer , Iñiguez Concepción , Serrano Oscar , Rhodes Timothy , Galmés Jeroni 
Published: October 2022

AbstractThe CO2-fixing enzyme Ribulose bisphosphate carboxylase-oxygenase (Rubisco) links the inorganic and organic phases of the global carbon cycle. In aquatic systems, the catalytic adaptation of algae Rubiscos has been more expansive and followed an evolutionary pathway that appears distinct to terrestrial plant Rubisco. Here, we extend this survey to differing seagrass species of the genus Posidonia to reveal how their disjunctive geographical distribution and diverged phylogeny, along with their CO2 concentrating mechanisms (CCMs) effectiveness, have impacted their Rubisco kinetic properties. The Rubisco from Posidonia species showed lower carboxylation efficiencies and lower sensitivity to O2 inhibition than those measured for terrestrial C3 and C4-plant Rubiscos. Compared with the Australian Posidonia species, Rubisco from the Mediterranean Posidonia oceanica had 1.5–2-fold lower carboxylation and oxygenation efficiencies, coinciding with effective CCMs and five Rubisco large subunit amino acid substitutions. Among the Australian Posidonia species, CCM effectiveness was higher in Posidonia sinuosa and lower in the deep-living Posidonia angustifolia, likely related to the 20%–35% lower Rubisco carboxylation efficiency in P. sinuosa and the two-fold higher Rubisco content in P. angustifolia. Our results suggest that the catalytic evolution of Posidonia Rubisco has been impacted by the low CO2 availability and gas exchange properties of marine environments, but with contrasting Rubisco kinetics according to the time of diversification among the species. As a result, the relationships between maximum carboxylation rate and CO2- and O2-affinities of Posidonia Rubiscos follow an alternative path to that characteristic of terrestrial angiosperm Rubiscos.
The unique sweet potato NAC transcription factor IbNAC3 modulates combined salt and drought stresses
Authors: Meng Xiaoqing , Liu Siyuan , Zhang Chengbin , He Junna , Ma Daifu , Wang Xin , Dong Tingting , Guo Fen , Cai Jing , Long Tiandan , Li Zongyun , Zhu Mingku 
Published: October 2022

Abstract
Plants often simultaneously experience combined stresses rather than a single stress, causing more serious damage, but the underlying mechanisms remain unknown. Here, we identified the stress-induced IbNAC3 from sweet potato (Ipomoea batatas) as a nucleus-localized transcription activator. IbNAC3 contains a unique activation domain whose MKD sequence confers transactivation activities to multiple other TFs and is essential for the activated expression of downstream target genes. Ectopic expression of IbNAC3 conferred tolerance to single and combined salt and drought stresses in Arabidopsis (Arabidopsis thaliana), and a group of NAM, ATAF1/2, and CUC2 (NAC) TFs, including ANAC011, ANAC072, ANAC083, ANAC100, and NAP, interacted with IbNAC3, and the specific domains responsible for each interaction varied. Intriguingly, IbNAC3 repressed the interaction among the five NACs, and knockout or mutation of ANAC011 and ANAC072 dramatically impaired combined stress tolerance. IbNAC3-ANAC072 and IbNAC3-NAP modules synergistically activated the MICROTUBULE-RELATED E3 LIGASE57 (MREL57) gene. Consistently, mutation of MREL57 and overexpression of WAVE-DAM-PENED2-LIKE7, encoding a target protein of MREL57, both remarkably impaired combined stress tolerance. Moreover, transgenic plants displayed abscisic acid (ABA) hyposensitivity by directly promoting the transcription of ENHANCED RESPONSE TO ABA 1, a key negative regulator of ABA signaling. The data unravel the unique IbNAC3 TF functions as a pivotal component in combined stress tolerance by integrating multiple regulatory events and ubiquitin pathways, which is essential for developing high-tolerant plants in natural environments.
First demonstration of a roller-driven timestamp mechanism for long-duration observations with high time resolution using large-area emulsion films
Authors: Oda M , Aoki S , Azuma T , Kato T , Nagahara S , Takahashi S , Yamada K , Yamamoto T , Yamashita M 
Published: October 2022

Abstract
A multi-stage shifter allows timestamped measurements by emulsion films, which have a thin medium and high resolution (&lt; 1μm). Using multiple layers of emulsion films that move at different speeds like hands of an analog clock, the shifter can create a unique positional displacement with respect to the time-track recorded. The time information of each track is obtained by reproducing each positional displacement by track reconstruction. We developed a new model of shifter with a lighter structure to enable a large aperture area and long-duration observation times by adding more layers. Operational testing suggested that the new shifter has a sub-second time resolution, which allows an emulsion gamma-ray telescope to obtain an imaging resolution within 1° (&gt; 80 MeV), like previous balloon experiments. Furthermore, by adding a layer which move at 100 μm s-1, it achieved the 0.1 s time resolution required for high-resolution imaging above 1 GeV. We also found the possibilities of an almost three-fold improvement in the spatial resolutions in track reconstruction compared with the conventional model and of achieving time resolution on a scale of tens of milliseconds, which would enable phase resolution of a pulsar.
The Fit-for-Purpose Model: Conceptualizing and Managing Chronic Nonspecific Low Back Pain as an Information Problem
Authors: Wand Benedict M , Cashin Aidan G , McAuley James H , Bagg Matthew K , Orange Gemma M , Moseley G Lorimer 
Published: October 2022

Abstract
Chronic nonspecific low back pain (LBP) is a complex and multifaceted problem. The following Perspective piece tries to help make sense of this complexity by describing a model for the development and maintenance of persistent LBP that integrates modifiable factors across the biopsychosocial spectrum. The Fit-for-Purpose model posits the view that chronic nonspecific LBP represents a state in which the person in pain holds strong and relatively intransient internal models of an immutably damaged, fragile, and unhealthy back, and information that supports these models is more available and trustworthy than information that counters them. This Perspective proposes a corresponding treatment framework for persistent pain that aims to shift internal models of a fragile, damaged, unhealthy, and unchangeable self toward the formulation of the back as healthy, strong, adaptable, and fit for purpose and to provide the system with precise and trustworthy evidence that supports this supposition while minimizing information that works against it.
Regulatory Limits to Risk Management
Authors: Sen Ishita 
Published: October 2022

Abstract
Variable annuities, the largest liability of U.S. life insurers, are investment products containing long-dated minimum return guarantees. I show that guarantees with similar economic risks are treated differently by regulation and these differences impact insurers’ hedging behavior. When the regulatory regime recognizes certain risks, insurers start to hedge these risks in a substantial way. For some guarantees, this involves hedging both interest rate and equity market risks. However, for others, it involves hedging only equity market risk. As the regulatory regime still does not recognize the interest rate risk of all guarantees, insurers remain exposed to substantial interest rate risk.
Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.
Concordance and Discordance in the Phylogenomics of the Wrasses and Parrotfishes (Teleostei: Labridae)
Authors: Hughes Lily C , Nash Chloe M , White William T , Westneat Mark W 
Published: October 2022

Abstract
Phylogenomic analysis of large genome-wide sequence data sets can resolve phylogenetic tree topologies for large species groups, help test the accuracy of and improve resolution for earlier multi-locus studies and reveal the level of agreement or concordance within partitions of the genome for various tree topologies. Here we used a target-capture approach to sequence 1088 single-copy exons for more than 200 labrid fishes together with more than 100 outgroup taxa to generate a new data-rich phylogeny for the family Labridae. Our time-calibrated phylogenetic analysis of exon-capture data pushes the root node age of the family Labridae back into the Cretaceous to about 79 Ma years ago. The monotypic Centrogenys vaigiensis, and the order Uranoscopiformes (stargazers) are identified as the sister lineages of Labridae. The phylogenetic relationships among major labrid subfamilies and within these clades were largely congruent with prior analyses of select mitochondrial and nuclear datasets. However, the position of the tribe Cirrhilabrini (fairy and flame wrasses) showed discordance, resolving either as the sister to a crown julidine clade or alternatively sister to a group formed by the labrines, cheilines and scarines. Exploration of this pattern using multiple approaches leads to slightly higher support for this latter hypothesis, highlighting the importance of genome-level data sets for resolving short internodes at key phylogenetic positions in a large, economically important groups of coral reef fishes. More broadly, we demonstrate how accounting for sources of biological variability from incomplete lineage sorting and exploring systematic error at conflicting nodes can aid in evaluating alternative phylogenetic hypotheses. [coral reefs; divergence time estimation; exon-capture; fossil calibration; incomplete lineage sorting.]
First Report of Cucurbit Aphid-Borne Yellows Virus Infecting Groundnut in Kenya
Authors: Mabele Anthony S. , Muyekho Francis N. , Were Hassan K. 
Published: October 2022

Cucurbit aphid-borne yellows virus (CABYV, genus Polerovirus, family Luteoviridae) causing cucurbit aphid-borne yellows disease (CABYD) in groundnut ( Arachis hypogaea) is characterized by interveinal yellowing symptoms in leaves. CABYV is transmitted by Aphis gossypii, Myzus persicae, and Macrosiphum euphorbiae. CABYV causes up to 80% yield loss, but there is no information available on its occurrence and serological and molecular characteristics in groundnuts. Two disease diagnostic surveys were conducted during the short and long rains seasons of 2020 and 2021 in Bungoma, Busia, Kakamega, and Siaya counties growing groundnut. Disease incidence and severity were scored, and collected data were analyzed using R software. Serological bioassays were performed using TAS-ELISA, and positive samples were pooled and processed with the transposon-based chemistry library preparation kit (Nextera XT, Illumina). Phylogenetic analyses and comparisons were performed using the MEGA X software. In the short rains season higher incidence (73.61%) was recorded than in the long rains season (42.65%). The CABYV isolates from Kenya clustered with other poleroviruses variedly. CABYV6-2 showed 94.5% nucleotide identity with CpPV2 isolate KX599164.1 from Burkina Faso and 83.4% identity with CABYV isolate MG257902.1 from Korea. This research provides evidence for the first report of CABYV infecting A. hypogaea relevant for development of better plant health management technologies for increased groundnut yield.
Parent Perceptions of a Pretend Play Intervention for Their Children With Cancer
Authors: HÖGLUND Anna T. , WITT Stefanie , QUITMANN Julia H. , FRYGNER-HOLM Sara 
Published: October 2022

ABSTRACT

Background
Although the rate of survival in childhood cancer today is close to 85%, a cancer diagnosis can still turn the world upside down for both children and parents. Often, children in oncology care are frustrated about their inability to control events and activities around them. Therapeutic pretend play has been suggested as a means to encourage children to express and handle emotions in a safe environment.

Purpose
This study was developed to describe and explore parents' experiences of a pretend play intervention that consisted of six to eight play sessions with a play facilitator administered to their children undergoing cancer treatment.

Methods
A descriptive qualitative method was used, including individual interviews with 15 parents.

Results
Three main categories were developed, including (a) experiences of joining the project, (b) perceptions of the play intervention, and (c) reflections on effects and implications, with subcategories evolved for each category. The parents experienced that the play sessions helped improve their children's communication skills and made them more capable of participating in their care. They appreciated that the intervention focused on the child's well-being and saw it as a positive break in their child's cancer treatment. It also helped them better reflect on their own situation.

Conclusions/Implications for Practice
According to the parents' experiences, pretend play can be a helpful tool for improving children's participation in their cancer care that strengthens their autonomy, emotional repertoire, and communication skills. However, the results also highlighted that some of the children did not fully understand the information provided about this study, which weakened the validity of their consent to participate. Thus, more work is needed on developing age-appropriate information to obtain participation consent from children. In addition, more knowledge is needed regarding how to appropriately include children with cancer in research in an ethically acceptable way.
A Chinese female patient with LGI1 and mGluR5 antibodies: A case report
Authors: Huo Tiantian , Luo Xintong , Zhao Jingru , Wang Tianjun , Chen Jinghong 
Published: October 2022

Rationale:
Anti-LGI1 antibody encephalitis and anti-mGluR5 are both uncommon encephalitis, and we report the first case of autoimmune encephalitis (AE) with dual seropositive antibodies of leucine-rich glioma-inactivated 1 (LGI1) and mGluR5.

Patient concerns:
We present a case of AE with dual seropositive antibodies of LGI1 and mGluR5 in a 65-year-old woman who presented with sudden onset left faciobrachial dystonic seizures and unresponsive for 5 hours.

Diagnosis:
The patient was diagnosed with anti-LGI1 AE and anti-mGluR5 AE mainly based on the clinical symptoms and further test of the antibody in serum and cerebral spinal fluid (CSF).

Interventions and outcomes:
The patient was treated with glucocorticoid intravenous drip. We also gave her the therapy of immunoglobulin (25 g q.d) for 5 days and anti-epileptic therapy. She had no more convulsions on the left side of the face and limbs. She did not complain of any uncomfort until July 18.

Lessons:
Early recognition of AE is crucial. Specific autoantibodies are associated with corresponding syndromes. Our patient was initially diagnosed with acute ischemic stroke. Therefore, we should conduct further study on the related symptoms of AE.
Prenatal diagnosis and genetic analysis of a fetus with Branchio-oto-renal syndrome: A case report
Authors: Tang Ping , Li Jiarui , Li Jun , Yang Juan , Zhu Jianjun 
Published: October 2022

Background:Branchio-oto-renal (BOR) syndrome is an autosomal-dominant disorder characterized by branchial arch anomalies, hearing loss, and kidney defects. Mutations in the human EYA1 gene have been reported associated with BOR syndrome. Here we identified that a novel variant, EYA1: NM_000503.4: c.827-1G > C (Intron 8, shear mutation) was associated with BOR in a fetus of a Chinese family.Case presentation:Prenatal ultrasound examination showed that both kidneys of the fetus were small and the echo of both kidneys was enhanced. The amount of amniotic fluid was normal, and no other structural abnormalities of the fetus were found. Fetal umbilical cord blood puncture was performed. No abnormality was found in karyotyping and chromosomal microarray analysis (CMA) results. Thus, we performed a trio-based whole exome sequencing (WES), and found that the fetus carried a novel homozygous variant, EYA1: NM_000503.4: c.827-1G > C (Intron 8, shear mutation), but the parents do not have this mutation. The variation sites of fetus and parents were verified by Sanger sequencing to clarify the source of pathogenic variation.Conclusion:Combined with fetal imaging examination, the novel variation of EYA1: NM_000503.4: c.827-1G > C is the cause of fetal renal dysplasia. This case report indicates that the early use of appropriate technology can clarify the etiology of fetal disease and guide prognosis consultation.
Quality evaluation of endometriosis guidelines using AGREE II
Authors: Lei Yan , Du Xin , Chen Dejun , Gao Yue , Lian Hongmei 
Published: October 2022

Background:
To systematically evaluate the guidelines for endometriosis published in the past decade, and to provide reference for the selection of guidelines for endometriosis through quality evaluation and comparison.

Methods:
PubMed database, Embase database, evidence-based medicine clinical practice guidelines (CPG) database and the National Institute for Health and Clinical Excellence in the United Kingdom were searched by computer from December 2012 to December 2020 to retrieve published endometriosis CPG published by professional institutions or organizations. The search languages are English and Portuguese. Two researchers evaluated the quality of included CPG according to appraisal of guidelines for research and evaluation (AGREE II). The evaluation includes 6 areas: scope and purpose, participants, rigor of formulation, clarity of expression, applicability and independence. The recommendation level of CPG is determined by the distribution of standardized scores in the above 6 areas.

Results:
A total of 8 articles on endometriosis CPG were included, including 5 guidelines and 3 consensuses, covering 5 countries in 2 continents; the publication year was 2013 to 2020. The average standardized scores of the scope and purpose, participants, rigor, clarity, applicability and independence of CPG were 77.1%, 52.8%, 50.5%, 86.8%, 31.3%, and 36.5%, respectively. Among the 8 CPGs, 1 was grade A (recommended), 5 were grade B (recommended after improvement), and 2 were grade C (not recommended). Seven CPG recommendations were based on expert consensus, and one was developed through detailed literature retrieval, analysis and evidence rating evaluation. There was little difference between the guidelines in terms of treatment-related recommendations.

Conclusions:
The quality of endometriosis CPG released in 2013 to 2020 is quite different, and some CPGs are not ideal in terms of rigor, applicability and independence. The guidelines issued by NICE in 2017 are A-grade recommendations. The standardized scores in various fields are high, and the formation process of CPG is the most standardized, which is worth learning and reference.