bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of pharmaceutically compounded oral caffeine on the impact of medication adherence and risk of readmission among preterm neonates: A single-center quasi-experimental study
Authors: Ambreen Gul , Kumar Manoj , Ali Amin , Shah Syed Akbar Ali , Saleem Syed Muzafar , Tahir Ayesha , Salat Muhammad Sohail , Aslam Muhammad Shahzad , Hussain Kashif 
Published: November 2022

Background
Caffeine is available in an ampoule, used via parenteral and enteral routes in preterm neonates to treat apnea of prematurity (AOP) in neonates of gestational age ≥ 35–40 weeks. A longer duration of therapy has a higher risk of medication non-adherence due to higher costs and inappropriate dosage forms. Pharmaceutically compounded oral caffeine (PCC) could be an appropriate alternate dosage form. The researchers aimed to determine the impact of PCC on medication-related factors influencing medication adherence (MA) and the frequency of hospital readmission with apnea (HRA) in preterm neonates.

Methods
We conducted a single-center quasi-experimental study for this quality improvement project using PCC among the preterm neonates admitted in a tertiary care level-III NICU at the Aga Khan University Hospital Karachi, Pakistan, received caffeine therapy, and survived at discharge. The researchers compared pre-PCC data (April-December 2017) with post-PCC data (April-Dec 2018) each for nine months, with three months intervals (January-March 2018) of PCC formulation and implementation phase. The study was conducted according to the SQUIRE2.0 guidelines. The Data were collated on factors influencing MA, including the cost of therapy, medication refill rates, and parental complaints as primary outcome measures. The Risk factors of HRA were included as secondary outcomes.

Results
After PCC implementation cost of therapy was reduced significantly from Rs. 97000.0 (729.0 USD) to Rs. 24500.0 (185.0 USD) (p<0.001), significantly higher (p<0.001) number of patients completed remaining refills (77.6% pre-phase vs 97.5% post-phase). The number of parental complaints about cost, ampoule usage, medication drawing issue, wastage, inappropriate dosage form, and longer duration of therapy reduced significantly in post-phase. HRA reduced from 25% to 6.6% (p<0.001). Post-implementation of PCC (RR 0.14; 95% CI: 0.07–0.27) was a significant independent risk factor for reducing HRA using a multivariate analysis model. Longer duration of caffeine therapy after discharge (RR 1.05; 95% CI: 1.04–1.04), those who were born in multiple births (RR 1.15; 95% CI: 1.15–1.15), and those who had higher number of siblings were other significant independent risk factors for HRA.

Conclusions
PCC dispensation in the appropriate dosage form at discharge effectively reduced cost, non-adherence to therapy, and risk of hospital readmissions. This neonatal clinical and compounding pharmacist-led model can be replicated in other resource-limiting setting.
Correlation between the tissue ghrelin presence, disease activity and laboratory parameters in ulcerative colitis patients; immunohistochemical study
Authors: Sahin Memduh , Erdogan Kivilcim Eren , Tekingündüz Emine 
Published: November 2022

Background
The aim of the study was to determine the differences in terms of ghrelin presence in the colon between the patients with ulcerative colitis (UC) and control patients.

Methods
Sixty-one UC and 15 control patients were included in the study. Immunohistochemical staining for ghrelin was investigated in colonic biopsy samples of UC and control patients. UC patients were subdivided into Group A (absence of ghrelin staining) and Group B (presence of staining for ghrelin in biopsy samples). Disease activity scores, laboratory parameters and quantitative ghrelin staining were compared in both groups of UC patients, as well as with the observations in control patients.

Results
Cells in colonic mucosa stained for ghrelin were identified in twenty-three (37.7%) UC patients, while this proportion in control patients was 6/15(40%). A significant difference was found between Groups A and B for serum albumin concentration but not for erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), hemoglobin concentration or leucocyte count. Mayo score/disease activity index (DAI) for UC were significantly higher in Group A than in Group B (p = 0.03).

Conclusions
There were no differences in the amount of colonic ghrelin staining between healthy individuals and UC patients. Colonic ghrelin staining in UC patients seems to be associated with the increased activity of this disease.
MENGEMBANGKAN WISATA ALAM POSONG MELALUI PENDEKATAN BRAND HEXAGON DI KABUPATEN TEMANGGUNG
Authors: Yunizar Innas Muhammad , Kismartini Kismartini , Rahman Amni Zarkasyi 
Published: November 2022

Setiap daerah dituntut untuk menjadi unik atau berbeda dengan daerah lainnya. Identitas suatu daerah, selalu terkait pada pemasaran dan branding wilayah tersebut. Sebuah tempat yang dapat menciptakan merek kuat dengan pencerminan identitasnya, maka akan menarik konsumen potensial, wisatawan, investor, ataupun penduduk, sehingga branding sendiri merupakan pembeda yang jelas menjadi ujung tombak bagi daya tarik suatu wisata. Indonesia sebagi negara yang memiliki banyak wilayah potensi pariwisata, harus dapat beradaptasi dan siap mengembangkan potensi tersebut dengan konsep place branding. Penelitian ini bertujuan untuk mendeskripsikan dan menganalisis efektivitas place branding wisata alam Posong dengan menggunakan konsep Branding Hexagon. Metode penelitian ini adalah penelitian deskriptif kuantitatif dan bentuk variabelnya adalah variabel tunggal. Artinya, tidak mencari pengaruh atau hubungan variabel lain tetapi bermaksud mendeskripsikan tentang efektiviras place branding wisata alam Posong di kabupaten Temanggung. Metode pengumpulan data menggunakan kuesioner untuk memudahkan peneliti dalam proses pengumpulan data. Subyek penelitian diambil sebanyak 100 orang dihitung berdasarkan rumus slovin sesuai jumlah pengunjung tahun 2021. Hasil penelitian menunjukkan bahwa place branding di Wisata Alam Posong berjalan dengan baik, hal tersebut karena Wisata Alam Posong memiliki daya tarik yang besar untuk kunjungi masyarakat. Meskipun begitu, ditemukan permasalahan pada indikator The Potential yang berkaitan dengan akses jalan menuju obyek wisata. Wisata alam posong perlu membenahi akses jalan, medan yang sempit dan menanjak, kemudian struktur jalannya masih berupa bebatuan dapat mengurangi kenyamanan pengunjung ketika berwisata di wisata alam posong.
Residual magnetic field as a source of information about steel wire rope technical condition
Authors: Mazurek Paweł , Roskosz Maciej 
Published: November 2022

Abstract
Research has been undertaken to analyze the possibilities of using the residual magnetic field, as a result of local changes in the electromagnetic properties of the rope material, for identification of steel wire rope technical condition. Under the influence of cyclically changing workloads, due to the effects of magnetomechanics, changes in electromagnetic properties occur both in the wires and in the entire rope. The article presents the use of magnetic sensors to determine the relationship between the number of steel wire rope bends and its magnetic field induction value. This knowledge, referred to as ropes working on real objects, allows us to determine the state of stress prevailing in them as well as their technical condition.
Understanding Family Firm Intentions to Use Private Equity: A Theory of Planned Behaviour Perspective
Authors: Graves Chris , Seet Pi-Shen , Michiels Anneleen 
Published: November 2022

Abstract
Although past research suggests that family firms are less likely to use private equity (PE) financing, further research is required to identify the underlying reasons for such behaviour. Using the theory of planned behaviour and based on the analysis of data collected from 254 family firms, we identify the factors that explain a family firm’s intentions to use PE. Family owners are more likely to plan to use PE when they have a favourable attitude toward PE, their intended succession strategy involves relinquishing control by selling the business sometime in the future, and they have a good understanding of PE.
The Socio-Pragmatics of Greetings in Turkish Folktales
Authors: Cetin Samet 
Published: November 2022

AbstractGreetings are linguistic and cultural universals. Every language and culture has a set of formulas or social and ritual acts practiced as greetings. Although cultural practices of greeting to achieve particular social goals may vary, the act of greeting, the paradigm itself, can be examined under two communicative functions. (1) trust/safety providing and (2) the power manipulation. This study examines greetings in Turkish folk tales and figures out their socio-pragmatic dynamics based on politeness theory and speech act theory.
„Vom Zarewitsch Chlor und der Rose ohne Dornen, die nicht sticht“. Das ‚russische‘ Märchen von Katharina II. im europäischen Kontext
Authors: Leingang Oxane 
Published: November 2022

Zusammenfassung
Der Beitrag widmet sich einem allegorischen Märchen vom Zarewitsch Chlor, das Katharina II. für ihr Enkelkind schrieb. Diese Kuriosität der Literaturgeschichte gilt nicht nur als das erste Kinderbuch überhaupt, das aus dem Russischen in andere Sprachen übersetzt wurde, sondern auch als das erste Kunstmärchen einer deutschsprachigen Autorin. Neben den märchentypischen Motiven und der Selbstinszenierung von Katharina II. rückt die europaweite Rezeption des Märchens in den Fokus.
Smoking behavior among junior high school students based on the theory of planned behavior in Madura, Indonesia
Authors: Sutha Diah Wijayanti , Prabandari Yayi Suryo , Padmawati Retna Siwi 
Published: November 2022

Abstract

Objective
This research aimed to assess attitudes, subjective norms, and intentions about early smoking behavior among junior and senior high school students in Sampang, Madura, Indonesia.

Content
Teenagers’ smoking behavior is a phenomenon that needs careful examination and is easily recognized today. In Indonesia, the frequency of teenage smokers aged 10–18 years is growing every year. This age group is essential since most regular smokers start to smoke at this age. Although the Indonesian government has made preventive efforts, the prevalence of tobacco use remains high and continues to rise among younger age citizens. This research employed descriptive analysis with a cross-sectional approach. A total of 174 teenagers were chosen to participate in this study using a purposive sampling approach among junior high and high school students in Sampang District who smoke. Data were collected using questionnaires and evaluated with statistical regression tests with 95% confidence intervals (CI).

Summary
The findings revealed that attitudes, subjective norms, and intentions were linked to early smoking behavior in teenagers in the Sampang District, Madura. The results were attitude (OR=5.27, 95% CI: 4.89–5.61), subjective norm (OR=1.78, 95% CI: 1.51–2.05), PBC (OR=2.05, 95% CI: 1.66–2.40), and intention (OR=4.16, 95% CI: 3.86–4.47). Early smoking behavior in Sampang is primarily driven by the impression of poor parental disruptive behavior and a strong urge to smoke among teenagers, along with significant peer support.

Outlook
These findings can be utilized to address some of the key issues identified in order to prevent smoking in teenagers by establishing an atmosphere that avoids the stimulation in smoking behavior.
Recent advances in perovskites-based optoelectronics
Authors: Liu Xiaoyan , Wang Yijie , Wang Yu , Zhao Yize , Yu Jinghao , Shan Xinyi , Tong Yi , Lian Xiaojuan , Wan Xiang , Wang Lei , Tian Pengfei , Kuo Hao-Chung 
Published: November 2022

Abstract
The development and utilization of perovskites are beneficial to improve or even change the optical properties of devices and obtain fascinating performances such as higher photoelectric conversion efficiency, better thermal stability, higher external quantum efficiency, more excellent remodeling, and flexibility. So, there are many articles on perovskite reviews having been reported from synthesis, properties to various applications (such as optoelectronic devices, electrical memristor, etc.). Based on the reported review of perovskites, this study will make a further supplement to the research progress of perovskites in visible light communication (VLC), optical neuromorphic devices, and highlight huge development prospects in these emerging fields in recent years. First, we briefly reviewed the preparation methods of common perovskite materials, followed by the optical and electrical characteristics. Then, the specific applications of optical properties based on perovskite materials are emphatically investigated, in addition to traditional photovoltaic devices, especially the latest cutting-edge fields of information encryption and decryption, VLC as well as optical memristive devices for photonic synapse and photonic neuromorphic computing. Finally, the main conclusions and prospects are given. Perovskite-based optical memristive devices are enabled to assist photonic neuromorphic calculations, showing huge potential application prospects in intelligent integrated chip fusing sensing, storage, and computing.
Radiation dose measurement on bone scintigraphy and planning clinical management
Authors: Sarihan Mucize , Abamor Evrim 
Published: November 2022

Abstract
Radiation has been used in a variety of different fields since its discovery. It is very important in medial sector for both diagnosis and also for treatment. In this study, the radiation dose rate emitted to the environment after radiopharmaceutical injection was determined using patients undergoing bone scintigraphy imaging. Radiation dose rate measurements were performed at different distances from the patient and at different levels of the patient. Measurements were done at different times to determine the relationship between radiation dose rate and time. The radiation dose rate emitted by the patient was measured after an average of 10.21, 42.36, and 76.28 min of injection. In order to see the relationship between radiation dose rate and distance, measurements were done at 25, 50, 100, and 200 cm distance from the patient. The measured average radiation dose rate at 1 m distance from the patients’ chest level and 10.21 min after radiopharmaceutical injection was 16.27 μSv h−1. Then, the average radiation dose rate decayed down to 13.65 μSv h−1 after 42.36 min, while the measured average radiation dose rate after 76.28 min was lower as 12.41 μSv h−1 at 100 cm from patient’s chest level.
Surface waves on a coated incompressible elastic half-space
Authors: Althobaiti Saad 
Published: November 2022

Abstract
Recently, Khajiyeva et al. (2018) studied the dynamics of surface wave propagation in a pre-stressed incompressible half-space when accompanied by both vertical and tangential loads. In this study, however, we extend the work of Khajiyeva et al. to include the presence of a coating layer above the half-space, upon which the loads are acted. Moreover, we prescribe sufficient perfect continuity conditions between the two layers, resulting in an inhomogeneous composite structure. Furthermore, related effective boundary conditions within the long-wave assumption are acquired for the model through the application of the asymptotic approximation method. Finally, approximate uncoupled pseudo-differential equations are derived on the surface, thereby admitting all the results of Khajiyeva et al. as limiting cases of concern.
In situ prepared composite of polypyrrole and multi-walled carbon nanotubes grafted with sodium polystyrenesulfonate as ammonia gas sensor with wide detection range
Authors: Zhao Huijie , Hong Lijie , Han Kaiyue , Yang Mujie , Li Yang 
Published: November 2022

Abstract
NH3 gas sensors with good sensing performance including wide detection range at room temperature are highly desirable for a large variety of applications. In this work, multi-walled carbon nanotubes grafted with sodium polystyrenesulfonate (PSSNa-MWCNTs) are prepared via a controlled radical polymerization and show good dispersibility in water. The composite of polypyrrole with PSSNa-MWCNTs (PPy/PSSNa-MWCNT) is prepared by in situ vapor phase polymerization of pyrrole to fabricate NH3 gas sensors. Effects of the content of PSSNa-MWCNTs, the concentration of the oxidant, polymerization time and temperature on the gas sensing properties of the composite are investigated at room temperature. It is revealed that the composite shows much higher response magnitude than the single components. Under optimal conditions, PPy/PSSNa-MWCNT exhibits very wide detection range from 5 to 2000 ppm, and good sensing linearity over 5–20 ppm and 20–100 ppm, respectively. Moreover, the electrical responses of the composite towards NH3 gas are fast (response and recovery time to 1000 ppm NH3 gas are 16.7 s and 143.6 s, respectively), reproducible and highly selective. The interactions between PPy and MWCNTs promote the charge transfer in the composite, leading to good sensing performance and exhibiting a synergetic effect.
An update to pain management after spinal cord injury: from pharmacology to circRNAs
Authors: Mazzone Graciela L. , Coronel María F. , Mladinic Miranda , Sámano Cynthia 
Published: November 2022

Abstract
Neuropathic pain (NP) following a spinal cord injury (SCI) is often hard to control and therapies should be focused on the physical, psychological, behavioral, social, and environmental factors that may contribute to chronic sensory symptoms. Novel therapeutic treatments for NP management should be based on the combination of pharmacological and nonpharmacological options. Some of them are addressed in this review with a focus on mechanisms and novel treatments. Several reports demonstrated an aberrant expression of non-coding RNAs (ncRNAs) that may represent key regulatory factors with a crucial role in the pathophysiology of NP and as potential diagnostic biomarkers. This review analyses the latest evidence for cellular and molecular mechanisms associated with the role of circular RNAs (circRNAs) in the management of pain after SCI. Advantages in the use of circRNA are their stability (up to 48 h), and specificity as sponges of different miRNAs related to SCI and nerve injury. The present review discusses novel data about deregulated circRNAs (up or downregulated) that sponge miRNAs, and promote cellular and molecular interactions with mRNAs and proteins. This data support the concept that circRNAs could be considered as novel potential therapeutic targets for NP management especially after spinal cord injuries.
Development of an Unpiloted Aircraft System–Based Sensing Approach to Detect and Measure Pavement Frost Heaves
Authors: Zaremotekhases Farah , Hunsaker Adam , Dave Eshan , Sias Jo E. 
Published: November 2022

Abstract
The combination of low temperatures, precipitation, and high-water table causes the formation of subsurface frost in pavements leading to the formation of frost heaves. This leads to significant damage to the structural integrity of the pavements and causes extensive surface roughness. Frost heaving is a common type of distress in cold climate regions, especially for road and airport infrastructures located in remote areas. Research discussed in this article focuses on determining the efficiency and accuracy of photogrammetry-based sensing systems to measure the extent of pavement frost heaves. The sensors are mounted on an unpiloted aircraft system (UAS) capable of providing measurements over large spatial domains in a single flight and are well suited for difficult-to-access regions. Experiments have been conducted on simulated heaves as well as actual cold climate pavement sections. The research described herein provides suitable UAS flight parameters for conducting frost heave measurements. Flight at an altitude of 50 m above the ground surface and a flight speed of 5 m/s with capturing images every 2 s resulted in more than 80 % front and side image overlap. The pavement surface profile has been constructed from extracted photogrammetry elevation data collected in three different seasons. Pavement surface roughness has been measured in terms of the international roughness index (IRI), and variation between measured IRI values has been evaluated during different seasons because of the formation of the frost heave distress. As it is expected, the IRI values increase as the cold season approaches. Moreover, the measured IRI values have been compared with the most recent available IRI data collected by an instrumented vehicle. The key outcomes of this work demonstrate that photogrammetry can reliably detect pavement frost heaves and provide high confidence in the future development of an automated system to measure pavement roughness that is attributable to frost heave distresses.
Head Orientation Influences Saccade Directions during Free Viewing
Authors: Reeves Stephanie M. , Cooper Emily A. , Rodriguez Raul , Otero-Millan Jorge 
Published: November 2022

AbstractWhen looking around a visual scene, humans make saccadic eye movements to fixate objects of interest. While the extraocular muscles can execute saccades in any direction, not all saccade directions are equally likely: saccades in horizontal and vertical directions are most prevalent. Here, we asked whether head orientation plays a role in determining saccade direction biases. Study participants (n = 14) viewed natural scenes and abstract fractals (radially symmetric patterns) through a virtual reality headset equipped with eye tracking. Participants’ heads were stabilized and tilted at −30°, 0°, or 30° while viewing the images, which could also be tilted by −30°, 0°, and 30° relative to the head. To determine whether the biases in saccade direction changed with head tilt, we calculated polar histograms of saccade directions and cross-correlated pairs of histograms to find the angular displacement resulting in the maximum correlation. During free viewing of fractals, saccade biases largely followed the orientation of the head with an average displacement value of 24° when comparing head upright to head tilt in world-referenced coordinates (t(13)= 17.63,p < 0.001). There was a systematic offset of 2.6° in saccade directions, likely reflecting ocular counter roll (OCR;t(13)= 3.13,p = 0.008). When participants viewed an Earth upright natural scene during head tilt, we found that the orientation of the head still influenced saccade directions (t(13)= 3.7,p = 0.001). These results suggest that nonvisual information about head orientation, such as that acquired by vestibular sensors, likely plays a role in saccade generation.