bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design thinking: strategy for digital transformation
Authors: Vendraminelli Luca , Macchion Laura , Nosella Anna , Vinelli Andrea 
Published: March 2022

Purpose
Digital advancements offer several opportunities to firms to gain competitive advantages, pushing them to transform their operating models. From the managerial standpoint, governing a digital transformation process is a complex task, as it means steering the process that goes from the exploration of the ample spectrum of opportunities that digital technologies provide, to the reduction of this complexity to a final set of actions to be designed and executed. As design theories are suited to solve complex problems, the purpose of this paper is to frame a design-driven approach to plan and execute a digital transformation.

Design/methodology/approach
This study pivots on an in-depth case study of a large Italian firm in the fashion sector that adopted design thinking to craft its digital transformation strategy and turn it into a list of projects to be executed.

Findings
Drawing from design theories, the authors framed a three-stage process (understanding reality, defining a digital transformation strategy and converting the digital transformation strategy into digital projects).

Research limitations/implications
The external validity of the study is limited due to the choice to rely on an in-depth single case study.

Practical implications
The framework provided offers a structure for managing the digital transformation through strategy development and execution. Moreover, practitioners and companies can evaluate if their digital transformation process is under control and reflect whether they have been giving the right attention to each of the three identified stages. They could follow the footsteps of EYEWEAR and adopt the proposed framework to design their company’s digital transformation process.

Social implications
This paper is supposed to help firms in reflecting on how to organize their digital transformation process. A positive transition to digital technologies enabled by the human-centeredness of design is likely to improve the quality of life of the people that belong to the transformed organization.

Originality/value
To the best of the authors’ knowledge, this study is one of the first research attempts at the crossroad between the fields of design, strategy and technology management and a groundwork for further studies to be conducted in this field.
Corporate Social Responsibility policies and practices on unvaccinated employees during the COVID-19 pandemic: case studies of Israel and United States
Authors: Litor Lilach 
Published: March 2022

PurposeThe article addresses the tension between Corporate Social Responsibility (CSR) and the right to work in times of the COVID-19 pandemic. Accordingly, it explores the operation of corporations in adopting policies of mandatory vaccination and the role of the courts regarding these CSR patterns.Design/methodology/approachThe article examines court case studies of CSR practices regarding unvaccinated employees during the COVID-19 pandemic in Israel and the United States.FindingsThe findings show that the Israeli system adopted the regulating for individual discretionary CSR approach, whereas the American system adopted the regulating for ethical-public CSR approach. Adopting the latter infringes upon the right to work of unvaccinated employees. While in Israel, the possibility of compelling employees to vaccinate is denied, in the American model, mandatory vaccination is possible. As opposed to the American model, in the Israeli model, there is an obligation to consider proportionate measures to isolate the employees while allowing them to continue working.Originality/valueThe article introduces two possible notions of regulating CSR in times of the pandemic – regulating for individual discretionary CSR which is labor-oriented and regulating for ethical-public CSR which is focused on public aspects. While the former posits that corporations should advance individual interests of employees and their right to work, the latter claims that corporations should advance the public interest in health. Following the problems resulting from the Israeli and American cases, the article draws on the lines for a suggested approach that courts should embrace.
Tourism-led rural gentrification: impacts and residents’ perception
Authors: Xu Yumei , Wang Chaohui , Zhang Tingting 
Published: March 2022

Purpose
This study aims to develop a measurement scale of tourism-led rural gentrification from the perspective of rural residents.

Design/methodology/approach
The procedure for developing the measurement scale included a thorough review of related literature on tourism-led rural gentrification and multiple stages of qualitative and quantitative investigations. A total of 1,080 rural residents in Huzhou and Huangshan participated in the project. The semi-structured interviews and questionnaire were applied to collect the data. This study analyzed the data with the methodologies of exploratory factor analysis, confirmatory factor analysis and structural equation modeling.

Findings
The measurement scale developed in this study included seven dimensions: Accelerated Ecological Awareness, Individual Behavior, Rural Economic Development, Enhanced Living Standards, Talents and Demographic Changes, Human and Cultural Shift and Cohesive Community.

Research limitations/implications
This measurement scale was developed and validated in China and may not be relevant in other contexts. The scale focuses on tourism-led rural gentrification only from the perspective of rural residents. The findings broaden the knowledge on tourism-led rural gentrification by researching the topic from the point of view of rural residents.

Practical implications
For policymakers and tourism enterprises, this study provides a valuable index for a full understanding of tourism-led rural gentrification. For investors, the research offers insights for priority investments to advance tourism development in rural regions.

Originality/value
This study is one of the few attempts to empirically measure tourism-led rural gentrification. The results improve on the knowledge about tourism-led rural gentrification in China.
Effect of B&B host responses to online reviews on subsequent reviews: the moderating effects of class level
Authors: Lan Tao , Feng Xiaodong , Zeng Zhimin 
Published: March 2022

Purpose
This study aims to focus on understanding how the characteristics of the bed and breakfast (B&B) host responses to online reviews impact the subsequent business performance of review volume, including volume, timeliness and length of responses.

Design/methodology/approach
The study constructs a theoretical framework to model for the relationships among characteristics of the B&B host responses, heterogeneity of B&B houses and subsequent reviews. The model is then examined by an econometric model using data from Ctrip.com.

Findings
Prompt and lengthy responses to online reviews increase the number of subsequent reviews, and the effects are larger for higher level houses. The main theoretical contribution is to build a model explaining how multiple attributes of the host responses can affect business performance and how these effects are moderated by the class levels of B&B houses, which are empirically tested by real data.

Practical implications
This study highlights managerial implications of host responses for online B&B business practices. For the higher-quality B&B houses, based on price and reviews, lengthy and timely responses are necessary, as tourists expect increased customer service from these hosts.

Originality/value
The research provides insights in understanding the mechanism of B&B host responses on subsequent reviews. To the best of the authors’ knowledge, this is the first study to demonstrate the moderating effect of price and volume of online reviews on responses.
Effects of a short-duration preprecipitation process prior to predeformation aging on the mechanical properties and corrosion resistance of Al-Cu-Mg-Ag alloy
Authors: Wang Yanqin , Wang Lulu , Liu Xiao Yan , Yang Hongru , Zhang Yuan , Zhu Xiaosong 
Published: March 2022

Purpose
The effects of the thermo-mechanical treatment on the properties and microstructure of the Al–Cu–Mg–Ag alloy were investigated.

Design/methodology/approach
A short-duration preprecipitation process is designed prior to predeformation aging. The novel predeformation aging (solution treatment + holding at 185 °C for 15 min+ rolling deformation + aging at 185 °C, also named T8) was performed on a heat-resistant Al–Cu–Mg–Ag alloy.

Findings
The purpose of this study indicate that a short-duration heat treatment before predeformation is beneficial to the precipitation of O during the aging process. The precursors of O during this process might pin the dislocation and cause the grains to orient along some specific direction, which might be advantageous to the precipitation of O while disadvantageous to that of θ′. This novel thermal-mechanical process could result in an increase in the quantity and decrease in the size of the precipitation of O, which leads to a remarkable strength effect. The potential increases while the current density decreases with an increase in the deformation amount, which implies a smaller intergranular corrosion rate. The fine deformed structure leads to an opposite behavior in the exfoliation corrosion test compared with that for intergranular corrosion.

Originality/value
The intergranular corrosion resistance of the Al–Cu–Mg–Ag alloy is enhanced, whereas the exfoliation corrosion resistance is reduced by novel predeformation aging.
Innovation information disclosure and stock price crash risk‐based supervision and insurance effect path analysis
Authors: Yu Ziqin , Xiao Xiang 
Published: March 2022

AbstractBecause of the long cycle of innovation, more investment, high risk and other characteristics, Chinese innovative firms tend to have a higher degree of information asymmetry, leading to frequent stock price ‘flash crashes’. This study investigates the impact of innovation information disclosure on stock price crash risk by examining the supervisory effect and insurance effect of innovation information disclosure for Growth Enterprises Market(GEM)‐listed firms in China from 2015 to 2019. We find that innovation information disclosure helps reduce firms' future stock price crash risk. The mechanism test finds that innovation information disclosure can exert both supervisory and insurance effects to reduce stock price crash risk. Specifically, after dividing innovation information disclosure into three categories: innovation advantage, content and risk disclosure, a vertical comparison reveals that the insurance effect of innovation advantage disclosure is more significant than the supervisory effect, while the opposite is true for innovation risk disclosure; a horizontal comparison reveals that the supervisory effect of innovation advantage, content and risk disclosure increases and the insurance effect decreases in order. The more types of innovation information disclosure, the more significant the effect of reducing stock price crash risk. Further analysis finds that the inhibitory effect of innovation information disclosure on stock price crash risk is stronger in firms with higher agency costs and higher innovation intensity in the industry. Our research has some insights into how to reduce the stock price crash risk of innovative companies in China.
Pollen exposure is associated with risk of respiratory symptoms during the first year of life
Authors: Gisler Amanda , Eeftens Marloes , de Hoogh Kees , Vienneau Danielle , Salem Yasmin , Yammine Sophie , Jakob Julian , Gorlanova Olga , Decrue Fabienne , Gehrig Regula , Frey Urs , Latzin Philipp , Fuchs Oliver , Usemann Jakob ,   the BILD study group
Published: March 2022

AbstractBackgroundPollen exposure is associated with respiratory symptoms in children and adults. However, the association of pollen exposure with respiratory symptoms during infancy, a particularly vulnerable period, remains unclear. We examined whether pollen exposure is associated with respiratory symptoms in infants and whether maternal atopy, infant's sex or air pollution modifies this association.MethodsWe investigated 14,874 observations from 401 healthy infants of a prospective birth cohort. The association between pollen exposure and respiratory symptoms, assessed in weekly telephone interviews, was evaluated using generalized additive mixed models (GAMMs). Effect modification by maternal atopy, infant's sex, and air pollution (NO2, PM2.5) was assessed with interaction terms.ResultsPer infant, 37 ± 2 (mean ± SD) respiratory symptom scores were assessed during the analysis period (January through September). Pollen exposure was associated with increased respiratory symptoms during the daytime (RR [95% CI] per 10% pollen/m3: combined 1.006 [1.002, 1.009]; tree 1.005 [1.002, 1.008]; grass 1.009 [1.000, 1.23]) and nighttime (combined 1.003 [0.999, 1.007]; tree 1.003 [0.999, 1.007]; grass 1.014 [1.004, 1.024]). While there was no effect modification by maternal atopy and infant's sex, a complex crossover interaction between combined pollen and PM2.5 was found (p‐value 0.003).ConclusionEven as early as during the first year of life, pollen exposure was associated with an increased risk of respiratory symptoms, independent of maternal atopy and infant's sex. Because infancy is a particularly vulnerable period for lung development, the identified adverse effect of pollen exposure may be relevant for the evolvement of chronic childhood asthma.
Does implementation of and adherence to enhanced recovery after surgery improve perioperative nutritional management in colorectal cancer surgery?
Authors: Besson Alex J. , Kei Christy , Djordjevic Aleksandra , Carter Vanessa , Deftereos Irene , Yeung Justin 
Published: March 2022

AbstractBackgroundMalnutrition is independently associated with poor outcomes in colorectal cancer (CRC) surgery including increased complications and length of stay (LOS). The purpose of this study was to identify changes to perioperative nutritional management and surgical outcomes post implementation of an enhanced recovery after surgery (ERAS) protocol.MethodsData on LOS and adherence to the ERAS protocol, including preoperative fasting time, nutritional assessment and supplementation was prospectively collected for the pre‐ERAS group who underwent surgery for CRC between February and August 2019. The post‐ERAS group involved a retrospective analysis of prospectively collected data of patients who underwent surgery between October 2019 and July 2020.ResultsOne hundred and thirty patients were included, (Pre‐ERASn = 42, Post‐ERASn = 88). A reduction in time to first solid intake by 1 day (P = 0.010), time to first bowel action (P = 0.007) and incidence of nausea (P < 0.001) was seen in the post‐ERAS group. Provision of postoperative oral supplements increased from 33.3% to 70.5% (P < 0.001) in the post‐ERAS group. Thirteen post‐ERAS patients had a ≥ 70% adherence to the ERAS protocol and this subgroup had an associated reduction in LOS, 6.5 (4) days to 5 (3),P = 0.020.ConclusionImplementation of the ERAS protocol improved perioperative patient care and outcomes. Early feeding was associated with reduced gastrointestinal symptoms without an increase in complications. Adherence to ERAS was associated with a reduction in LOS. Further research is required to evaluate the role of preoperative nutritional screening and intervention within an ERAS protocol.
The health‐related quality of life changes following surgery in patients with colorectal cancer: a longitudinal study
Authors: Tang Howard , Besson Alex , Deftereos Irene , Mahon Bede , Cho Jin , Faragher Ian , Gough Karla , Yeung Justin 
Published: March 2022

AbstractBackgroundColorectal cancer (CRC) is commonly treated with surgery and its success is frequently defined by cure rates. Impact on other aspects of health and wellbeing are less frequently considered in clinical practice. Patient‐reported outcome measures (PROMs) provide a useful means of assessing such impacts. This study examines changes in health‐related quality of life (HRQoL) after surgical resection using PROMs.MethodsA prospective, longitudinal study was undertaken in 49 adults receiving curative surgery for CRC. Participants completed the Functional Assessment of Cancer Therapy‐Colorectal (FACT‐C) before surgery, and at 2 to 4 weeks, 3 and 6 months post‐surgery. Linear mixed models were used to analyse FACT‐C wellbeing and subscale scores.ResultsPatients reported a clinically important deterioration in functional and physical wellbeing 2 to 4 weeks post‐surgery (both P < 0.05); differences at 6 months after surgery were trivial. Conversely, patients reported clinically important improvement in emotional wellbeing at 2 to 4 weeks post‐surgery; this improvement was sustained at 3 and 6 months post‐surgery (all P < 0.05). For social wellbeing and colorectal cancer‐specific concerns, changes from before surgery at follow‐up assessments were not statistically significant (all P > 0.05).ConclusionWhile physical aspects of HRQoL are affected in the short term by CRC surgery, clinically significant improvement in emotional wellbeing are reported early (2 to 4 weeks post‐surgery). Future research may help identify patients who are at greater risk of surgical impacts on health and wellbeing.
Just Transitions: A Political Ecology Critique
Authors: Bouzarovski Stefan 
Published: March 2022

Abstract“Green deals” to promote socially inclusive decarbonisation have captured the imagination of public intellectuals and advocates across the political spectrum. Such programmes are often premised upon the concept of “just transitions”, which aims to reconcile environmental and social concerns in the movement towards a low‐carbon future. I respond to some of the underlying tensions that underpin dominant discourses in this domain by foregrounding collective, disruptive, and non‐capitalist forms of infrastructural transformation in the energy domain. I discuss possibilities for a more egalitarian politics and shared environmental commons in the articulation of residential energy efficiency and housing upgrades with the aid of insights from the political ecology literature, and examples from activist praxis across Europe and North America. More broadly, I highlight how well‐known contradictions of labour, environmental sustainability, and economic transformation are complicated by encounters with climate and energy circulations.
Uterine conservative–resective surgery for selected placenta accreta spectrum cases: Surgical–vascular control methods
Authors: Aryananda Rozi Aditya , Aditiawarman Aditiawarman , Gumilar Khanisyah Erza , Wardhana Manggala Pasca , Akbar M. Ilham Aldika , Cininta Nareswari , Ernawati Ernawati , Wicaksono Budi , Joewono Hermanto Tri , Dachlan Erry Gumilar , Bachtiar Citra Aulia , Kurniawati Devita , Virdayanti Dian Puspita , Ariani Grace , Dekker Gustaaf Albert , Sulistyono Agus 
Published: March 2022

AbstractIntroductionThe incidence of placenta accreta spectrum (PAS) has increased, but the optimal management and the optimal way to achieve vascular control are still controversial. This study aims to compare maternal outcomes between different methods of vascular control in surgical PAS management.Material and methodsA retrospective cohort study on consecutive cases diagnosed with PAS between 2013 and 2020 in single tertiary hospital. The final diagnosis of PAS was made following preoperative ultrasound and confirmation during surgery. Management of PAS using cesarean hysterectomy with internal iliac artery ligation (IIAL) was compared with two types of vascular control in uterine conservative–resective surgery (IIAL vs identification–ligation of the upper vesical, upper vaginal, and uterine arteries).ResultsOver an 8‐year period, 234 pregnant women were diagnosed with PAS meeting the inclusion criteria. Uterine conservative–resective surgery (200 cases) was associated with lower mean blood loss compared with cesarean hysterectomy with IIAL (34 cases) in all PAS cases (1379 ± 769 mL vs 3168 ± 1916 mL; p < 0.001). In sub‐analysis of the two uterine conservative–resective surgery subgroups, the group with identification–ligation of the upper vesical, upper vaginal, and uterine arteries had a significantly lower blood loss compared with uterine conservative–resective surgery with IIAL (1307 ± 743 mL vs 1701 ± 813 mL; p = 0.005). Women in the hysterectomy with IIAL group had more massive transfusion (35.3% vs 2.5%; p < 0.001; odds ratio [OR] 21.3, 95% confidence interval [CI] 6.9–66), major blood loss (>1500 mL) (70.6% vs 34%, p < 0.001; OR 4.7; 95% CI 2.1–10.3), catastrophic blood loss (>2500 mL) (64.7% vs 12.5%;p < 0.001; OR 12.8, 95% CI 5.7–29.1), other complications (32% vs 12.4%; p = 0.007; OR 3.4, 95% CI 1.5–7.7), and intensive care unit admission (32.4% vs 1.5%; p < 0.001; OR 31.4, 95% CI 8.2–120.7) compared with the uterine conservative–resective surgery groups. The identification–ligation of the upper vesical, upper vaginal and uterine arteries had a significant lower risk for major blood loss (30.5% vs 50%; p = 0.041; OR 0.44, 95% CI = 0.2–0.9) compared with IIAL for vascular control of uterine conservative–resective surgery.ConclusionsCesarean hysterectomy is not the default treatment for PAS, PAS with invasion above the vesical trigone are suitable for uterine conservative–resective surgery with upper vesical, upper vaginal and uterine artery vascular control.
TMEM139 prevents NSCLC metastasis by inhibiting lysosomal degradation of E‐cadherin
Authors: Zhang Shuai , He Yunlong , Xuan Qijia , Ling Xiaodong , Men Kaiya , Zhao Xu , Xue Dinglong , Li Ling , Zhang Yingying 
Published: March 2022

AbstractNon‐small‐cell lung cancer (NSCLC) accounts for approximately 85% of all lung cancer cases and has the highest mortality rate among all solid tumors. It is characterized by early metastasis, and investigations of the molecular mechanisms underlying the progression and metastasis of NSCLC are urgently needed for the development of therapeutic targets. Here, we report that the transmembrane protein TMEM139 is significantly downregulated in NSCLC and that reduced expression of TMEM139 is correlated with a poor prognosis in NSCLC patients. Mechanistically, we found that TMEM139 directly interacts with E‐cadherin at the plasma membrane and at focal adhesion sites. Moreover, TMEM139 can prevent the lysosomal degradation of E‐cadherin, which inhibits epithelial‐mesenchymal transition, migration and invasion of NSCLC cells both in vitro and in vivo. Our study not only expands our understanding of NSCLC metastasis but also provides a foundation to develop novel therapeutic strategies.