bluuebunny/crossref_metadata_2025_split huggingface dataset:
NADIEM MAKARIM’S FIRST SPEECH AS THE MINISTER OF INDONESIA EDUCATION AND CULTURE: SPEECH ACT ANALYSIS
Authors: Nugraha Intan Siti , Citraresmana Elvi 
Published: April 2022

<span>The appointment of Nadiem Makarim as the new Minister of Education and Culture for Jokowi’s cabinet 2019-2024 term has been surprising. Although the background of the chosen Minister is not from educational sector as his predecessors, this digital venture entrepreneur’s presence in ministerial position brings hope on innovation and solutions that have never been explored before in Indonesia’s Educational system. Nadiem’s first speech in his inauguration as Minister of Education and Culture about his 100-day’s plans in attempts to improve Indonesia’s Education has drawn public attention. Hence, this study is aimed to investigate speech acts produced in Nadiem Makarim’s first speech as minister, especially their types and the implied meaning. Descriptive qualitative research design was employed in this study to get description of linguistics phenomenon. The data was the transcript of Nadiem Makarim’s speech. The data were analyzed based on theory of speech acts proposed by Searle (1976). The result shows to some extends which firstly commissive speech acts are dominantly occupied in the speech. Secondly, commissive speech acts are mostly realized as promise on his plan as the new Minister and assurance about his capability of being Minister with the promises he made even he does not come from Education field.</span>
MENINJAU PENERAPAN SAK EMKM PADA UMKM DI INDONESIA
Authors: Manehat Beatrix Yunarti , Sanda Fulgensius Oswin 
Published: April 2022

Kontribusi UMKM pada pertumbuhan ekonomi nasional terkategori signifikan. Untuk itu, IAI mengeluarkan SAK EMKM sebagai standar akuntansi keuangan yang khusus untuk UMKM agar para pelaku UMKM terbantu dalam kinerja keuangannya. SAK EMKM diharapkan dapat membantu para pelaku UMKM dalam peningkatan literasi keuangan, memperingkas pelaporan keuangan, serta meningkatkan kredibilitas laporan keuangan. Laporan keuangan yang akuntabel dan komprehensif sebagaimana yang telah diatur standarnya dalam SAK EMKM akan lebih cepat menarik kepercayaan pemodal yang dapat mendukung kemajuan UMKM. Dengan demikian penelitian ini ditujukan untuk mengetahui penerapan SAK EMKM pada UMKM di Indonesia. Pertanyaannya adalah sudahkah UMKM menggunakan SAK EMKM dalam kegiatan akuntansi di usahanya. Penelitian menggunakan metode kajian kepustakaan (library research) dimana data penelitian diambil dari buku, jurnal dan literatur lain terkait topik penelitian. Hasil penelitian menunjukkan bahwa sebagian besar UMKM di Indonesia belum menerapkan SAK EMKM. Berdasarkan telaah literatur, tidak hanya UMKM di bagian timur Indonesia, tetapi UMKM yang terletak di Indonesia Barat maupun Indonesia Tengah banyak yang belum menerapkan SAK-EMKM. Terdapat berbagai macam alasan tidak diterapkannya SAK EMKM namun umumnya adalah karena keterbatasan dan rendahnya kualitas sumber daya manusia.
Public knowledge and attitudes toward automated external defibrillators use among first aid eLearning course participants: A survey
Authors: Wang Yun-Ming , Lin Li-Ting , Jiang Jing-Hao , Jiang Yi , Jin Xiao-Qing 
Published: April 2022

Abstract
ObjectiveSurvival from out-of-hospital cardiac arrest (OHCA) often depends on the effective and immediate use of automated external defibrillators (AEDs). Given that there have been few studies about AED use in China, the purpose of this study is to investigate the knowledge and attitudes regarding AED use among the Chinese public, then provide an effective suggestion for AED education strategies and legislation.MethodThe online survey was conducted among Chinese participants of the First Aid eLearning courses in June 2020.ResultA total of 2565 (95.00%) surveys were completed, only 23.46% of respondents with non-medical related respondents reported having attended previous AED training courses. Regarding the basic knowledge of AEDs, few respondents (12.28%, n=315) could answer all four questions correctly. 95.67% (n=2454) were willing to learn AED use. Even if without the precondition of being skilled in AEDs, the female was more likely to rescue OHCA patients than the male(p=0.003). Almost all respondents (96.65%) showed a strong willingness to rescue OHCA patients with training in using AEDs. The top four barriers to rescuing OHCA patients were lack of practical performing ability (60.47%), fear of hurting patients (59.30%), inadequate knowledge of resuscitation techniques (44.19%), and worry about taking legal responsibility (26.74%).ConclusionOur study reflects a deficiency of AED knowledge among the general public in China. However, positive attitudes towards rescuing OHCA patients and learning AED use were observed, which indicates that measures need to be taken to disseminate knowledge and use of AEDs.
Genomic prediction ability and genetic parameters for residual feed intake calculated using different approaches in Nellore beef cattle
Authors: Brunes Ludmilla Costa , de Faria Carina Ubirajara , Magnabosco Claudio Ulhoa , Lobo Raysildo Barbosa , Peripolli Elisa , Baldi Fernando 
Published: April 2022

Abstract
This study aimed to estimate genetic parameters and the prediction ability and bias of the genomic values for residual feed intake (RFI) using genotypic and phenotypic records from 8,354 Nellore animals. The RFI was calculated using a regression equation for each test (RFItest) and for the whole population (RFIpop). An analysis of variance (ANOVA) using the same dataset and number of records was performed to verify the adequacy of the regression equations applied to estimate the RFItest and RFIpop. The (co)variance components were obtained using the single-step genomic best linear unbiased prediction (ssGBLUP) under single and two-trait animal model analyses. The ssGBLUP method was used for the genomic prediction and the cross-validation method as a validation strategy. The prediction ability and bias were estimated to compare the RFItest and RFIpop genomic breeding values (GEBVs). The RFIpop ANOVA showed a higher significance level (p < 0.0001) than did the RFItest for the fixed effects. The RFIpop displayed higher additive genetic variance estimated than the RFItest, although the RFIpop and RFItest displayed similar heritabilities. Overall, the RFItest showed higher residual correlations with growth, reproductive and carcass traits, while the RFIpop displayed higher genetic correlations with such traits. The GEBV for the RFItest was slightly biased than that obtained for the RFIpop. The method of calculating the RFI influences the decomposition and estimation of variance components, and genomic prediction. The genetic correlations between RFIpop and RFItest were high, implying that changes in sires ranking and genetic response are expected using one or the other. The application of RFIpop would be more appropriate for genetic evaluation purpose to adjust or correct for non-genetic effects and to decrease the prediction bias.
Evaluation of future rainfall over Southeast Asia using the CMIP6 multi-model ensemble
Authors: ONA Bhenjamin Jordan , Raghavan Srivatsan V , Liu Senfeng , Nguyen Ngoc Son 
Published: April 2022

Abstract
A multi-model ensemble from the new Coupled Model Intercomparison Project Phase 6 (CMIP6) models was utilized to determine the future changes in precipitation over Southeast Asia. The changes are computed for the three (3) future time slices (2021–2040, 2041–2060, and 2081–2100) under four (4) different scenarios based on the Shared Socioeconomic Pathways (SSPs): 1-2.6, 2-4.5, 3–7.0, and 5-8.5. Our results indicate that future rainfall in the SEA-averaged region could increase by about 4%, 5%, 6%, and 9% towards the end of the century relative to the present-day average (1995–2014) under SSP1-2.6, 2-4.5, 3–7.0, and 5-8.5, respectively. Among all scenarios, SSP3-7.0 widely shows remarkably dry conditions whereas SSP5-8.5 suggests extremely wet conditions on different time scales. Simulations revealed that large areas of the mainland SEA, the Philippines, and maritime Indonesia would tend to be drier in the near-term (2021–2040) and mid-term (2041–2060) during DJF and MAM but relatively wetter in the mid-term during JJA and SON, in a warmer climate. A clear dissociation of wet and dry areas is expected in the far-term period (2081–2100). The drying (wetting) condition over these regions is caused by a minimal (significant) increase in atmospheric moisture content accommodated with suppressed (enhanced) monsoon flow. Changes in the annual cycle indicate that future monsoon could also experience significant increases in rainfall. Changes in rainfall are also found to be sensitive to global mean temperature. The responses to future rainfall changes per degree Celsius of warming are at the rate of 8.9%, 6.3%, 3.6%, and 2.7% under SSP1-2.6, 2-4.5, 3–7.0, and 5-8.5, respectively.
The Value of Preoperative Neutrophil to Lymphocyte Count Ratio (NLR) in Assessing the Prognosis of Postoperative Patients with Non-B non-C Hepatocellular Carcinoma
Authors: chen wei , Tan Xiao-ping , fu ping , Jia Shou-wei 
Published: April 2022

Abstract
Background: The prognostic impact of the preoperative neutrophil to lymphocyte ratio (NLR) in patients with non-B, non-C hepatocellular carcinoma (NBNC-HCC) who undergo radical resection is unclear. This study elucidates the prognostic value of NLR in patients undergoing radical resection for NBNC-HCC.Methods: A total of 212 patients who were treated at the Cancer Center of Sun Yat-sen University from January 1998 to December 2007 were included in this study, and all patients underwent liver tumour resection and had postoperative pathological confirmation of HCC. The 212 patients were divided into four groups according to their NLR and HBsAg. The clinicopathologic and survival characteristics of the patients in Group 4 were compared with those in Groups 1-3.Results: There were statistically significant differences in age, drinking, body mass index (BMI), diabetes, metabolic syndrome, ALT, AST, tumour size, and secondary tumour (P<0.05) between Group 1 (NBNC-AFP(-) vs. B-AFP(+)). The univariate analysis showed that NLR, BMI, drinking, AST, tumour size, secondary tumour and portal violation (P<0.05) were factors affecting the disease free survival (DFS) in postoperative HCC patients. A Cox multivariate regression analysis showed that tumour size and secondary tumour (p<0.05) were independent factors influencing DFS after surgery. The univariate analysis showed that BMI, AST, tumour size, secondary tumour and portal violation (p<0.05) were factors that affected both DFS and OS in NBNC-NLR (-)-HCC patients after surgery, and in addition, the multifactor analysis using a Cox model showed that NLR, secondary tumour and BMI (p<0.05) were independent influences on the postoperative DFS in patients with NBNC-NLR (-)-HCC. The Kaplan–Meier survival analysis showed that the NBNC-NLR(-)-HCC patients had the highest rate of DFS among the four patient groups (p<0.05). The 1-, 3-, 5- and 10-year DFS rates for the NBNC-NLR(-)-HCC patients were 85.6%, 68.5%, 43.5% and 34.8%, respectively. The NBNC-NLR(-)-HCC patients had a higher postoperative DFS than the B-NLR(+)-HCCNBNC-NLR(+)-HCC and B-NLR(-)-HCC patients (p<0.05). The DFS rates at 1, 3, 5 and 10 years after surgery were 85.6%, 68.5%, 43.5% and 34.8% for the NBNC-NLR (-)-HCC group, respectively.Conclusion: The preoperative NLR is a valid prognostic indicator for patients with non-B non-C-HCC undergoing radical resection.
Mind the gap: Nodes of Ranvier are remodeled by chronic psychosocial stress and neuronal activity
Authors: Koskinen Maija-Kreetta , Laine Mikaela , Abdollahzadeh Ali , Gigliotta Adrien , Mazzini Giulia , Journee Sarah , Alenius Varpu , Trontti Kalevi , Tohka Jussi , Hyytiä Petri , Sierra Alejandra , Hovatta Iiris 
Published: April 2022

Abstract
Differential expression of myelin-related genes and changes in myelin thickness have been demonstrated in mice after chronic psychosocial stress, a risk factor for anxiety disorders. To determine whether and how stress affects structural remodeling of nodes of Ranvier, another form of myelin plasticity, we developed a 3D reconstruction analysis of node morphology in C57BL/6NCrl and DBA/2NCrl mice. We identified strain-dependent effects of chronic stress on node morphology, including elongation of paranodes in the medial prefrontal cortex (mPFC) in DBA/2NCrl mice. Furthermore, chronic chemogenetic activation of the ventral hippocampus-to-mPFC pathway resulted in increased risk assessment behavior and shortened paranodes specifically in stimulated axons, providing a direct link between anxiety-like behavior and remodeling of the nodes. Altogether, our data demonstrate genetic regulation of nodal remodeling in stress and suggest an activity-dependent regulation of paranodes in anxiety-related circuits. Nodal remodeling may thus contribute to the aberrant circuit function associated with anxiety disorders.
Effects of Fatigue, Rumination Thinking and Sleep Quality on the Hopelessness of Advanced Tumour Patients‘ Family Caregiver
Authors: CAO Zhaoming , WANG Yingchun , ZHANG Huijun 
Published: April 2022

Abstract
Objectives: To explore the relationship between fatigue, rumination, sleep quality and hopelessness in family caregivers of patients with malignant tumor, and to provide theoretical basis for maintaining their physical and mental health. Methods: Caregivers of malignant tumor patients who met the inclusion criteria in three Grade-A hospitals in Liaoning Province were investigated with Beck hopelessness scale (BHS), fatigue Scale-14 (FS-14), Nolen-Hoeksema ruminative responses scale (RRS) and Pittsburgh sleep quality index (PSQI), SPSS 26.0 was used to analyze the data, and Amos 22.0 was used to fit the structural equation model. Result: The main caregivers of patients with malignant tumor had a higher degree of hopelessness, and fatigue, sleep quality and rumination were positively correlated with the sense of hopelessness (r = 0.483-0.906; r = 0; P<0.05）; Fatigue and sleep quality can indirectly affect hopelessness through rumination thinkingn, and hopelessness has a direct effect on sleep. Conclusion: There are multiple action paths between fatigue and sleep quality, rumination thinkingn and hopelessness, which can maintain their physical and mental health and avoid hopelessness by improving their sleep quality, alleviating their fatigue and psychological counseling.
Automated Electrocardiogram Signal Quality Assessment Based on Fourier Analysis and Template Matching
Authors: Menon Kartikeya M. , Das Subrat , Shervey Mark , Johnson Matthew , Glicksberg Benjamin S. , Levin Matthew A. 
Published: April 2022

Abstract
Continuous electrocardiogram (ECG) recordings, which measure the electrical activity of the heart, are increasingly used to predict clinical outcomes via machine learning and artificial intelligence. [1-3] Raw ECG data can have a variety of interference artifacts which, if unattended to, can obscure or invalidate the results of machine learning algorithms. Current ECG de-noising routines focus primarily on how to purify ECG signals, but not on how to classify and excise regions of unusable voltage data. [4] Here we demonstrate a new method to quantitatively assess the quality of an ECG. We found that approximating a Fourier series to the QRS complex and cross-correlating this kernel sequentially with two-second intervals of the lead II ECG yields a metric that can be used to distinguish sections of data as low-or high-quality signal. The algorithm was developed on independently annotated ECG data, subdivided into two-second intervals (“epochs”), from ten patients admitted to the Mount Sinai Hospital. It was found to be 99% sensitive and 98.9% specific in classifying epochs into either noise or signal in 1,000 test epochs. This algorithm can be used to accelerate machine learning modeling that uses ECG data and lower the burden of pre-processing in research. Given its memory and run-time efficiency (demonstrably O(n)), this routine can be an effective starting point for real-time and continuous evaluation of ECG data using machine learning.
Synchronicity and peer-reviewed assignments in online scientific writing training with limited resources: a four-arm blinded randomized controlled trial with one-year follow-up
Authors: Hanafi Ibrahem , Kheder Kheder , Sabouni Rami , Nafouri Maarouf Gorra Al , Hanafi Bayan , Alsalkini Marah , Kenjrawi Yazan , Albkhetan Huda , Halabi Marwan Al 
Published: April 2022

Abstract

Introduction:Syrian medical research synthesis is marginal compared to neighboring countries and faces numerous obstacles that have been intensified by the Syrian armed conflict. Perceived research barriers include the lack of mentorship and academic writing skills. We evaluate the outcomes of a peer-run academic writing and publishing workshop, and contrast training synchronicity and its supplementary peer-reviewed assignments. Methods:This randomized controlled trial studied an online workshop that targeted under- and post-graduate medical and paramedical students at all Syrian universities. Blinded participants were randomized into four arms; Two arms attended the workshop synchronously, and the others asynchronously. One arm in each group undertook peer-reviewed scientific writing exercises (active), while the other two self-reviewed the same exercises (passive). Objective knowledge and subjective confidence in the learnt skills were assessed before the workshop, and one month and one year after it.Results: One-hundred-twenty-one participants completed the workshop, which was effective in improving their knowledge (P<0.001) and confidence (P<0.001). The post-course measures of the synchronous and asynchronous groups were similar. Completing the assignments resulted in higher knowledge (P=0.005) and confidence (P=0.003) only in the active groups. Moreover, participants who joined the peer-review process gained higher knowledge (P<0.001). At one-year-follow-up, the participants showed stability of the objective and subjective gains.Conclusion:The investigated training was beneficial regardless of the methods of attendance (i.e., synchronicity). Participation in supplementary exercises, especially when associated with peer-review, improved knowledge and confidence. This workshop proves a utilizable effective cheap alternative to improve scientific writing skills with limited resources and expertise.
The functional use of the arms of patients with breast cancer after surgical treatment and their behaviors to prevent lymphedema
Authors: Çolak Hava , Kızılırmak Aynur , Karadağ Songul 
Published: April 2022

Abstract
Purpose
The aim of this descriptive study was to determine the functional use of the arms of patients with breast cancer after surgical treatment and their behaviors to prevent lymphedema.
Methods
The study was conducted with 125 patients. The data were collected by using the Individual Information Form and the Turkish version of the Disabilities of the Arm, Shoulder and Hand Questionnaire-DASH Problems. Chi square, Fisher exact and Independent-Samples t test were used for statistical evaluation of the data.
Results
Lymphedema was detected in 21% of the women with breast cancer after surgical treatment. There was no significant difference between exercise status and lymphedema development of the patients, but there was a significant difference between exercise duration and the presence of lymphedema (p < 0.05). The DASH mean score of the women in the study was found to be 25.57 ± 15.86. The patients with lymphedema had higher DASH score and had more arm weakness.
Conclusions
It is recommended that nurses give training and consultancy to women with breast cancer and inform patients to do the recommended exercises by regularly following up them after surgical treatment.
Association between Organochlorine Pesticides and Nonalcoholic Fatty Liver Disease in the National Health and Nutrition Examination Survey 2003–2004
Authors: Sang Hyunji , Lee Kyu-Na , Jung Chang Hee , Han Kyungdo , Koh Eun Hee 
Published: April 2022

Abstract
While endocrine disruptors are emerging as a cause of nonalcoholic fatty liver disease (NAFLD), little is known about the link between NAFLD and organochlorine pesticides (OCPs), one of the endocrine disruptors. We retrospectively analyzed the National Health and Nutrition Examination Survey 2003–2004 conducted in the United States. Outcomes were differences in baseline demographics in participants with or without NAFLD, adjusted odds ratios for fatty liver index (FLI) ≥ 60 according to OCP concentration, correlation between OCP exposure and each variable constituting FLI, comparison of liver enzyme levels by OCP substance, and the association between OCP exposure and hepatic fibrosis. Of the 1512 participants, 579 had FLI ≥ 60 and were deemed to have NAFLD. After adjusted logistic regression, oxychlordane showed a higher risk of NAFLD with increasing serum concentrations. p,p’-DDE and trans-nonachlor were not significantly correlated with NAFLD; for mirex, the highest prevalence of NAFLD was observed in the lowest concentration quartile. Among the OCPs, oxychlordane showed the most pronounced association with the levels of each component of FLI and liver enzymes. None of the OCPs were significantly associated with hepatic fibrosis. In conclusion, among various OCPs, exposure to oxychlordane was significantly associated with the presence of NAFLD.
The Control Matrix
Authors: Barbini Francesco M. , Fioretti Guido , Vitali Beatrice 
Published: April 2022

Abstract
Matrix structures are generally designed and adopted in order to improve flexibility in spite of potential conflicts and substantial coordination costs. However, there exist hints that in some cases matrix structures, or at least portions of matrix structures, are adopted precisely in order to generate conflicts and competition that allow for better control.We approached this issue by means of a twofold investigation. First of all, we analysed the published organization charts of Forbes 2000 world’s largest firms. Secondly, we submitted a questionnaire to organizational consultants.Our findings suggest that, in some instances, the centralized functions of large multidivisional companies are used as additional authority lines that generate partial matrix structures. These structures make decision-making more difficult, but allow top management to exert greater control.JEL: L20, L22, L25