bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Classification for Progression to Subfoveal Geographic Atrophy in Dry Age-Related Macular Degeneration Using Machine Learning–Enabled Outer Retinal Feature Extraction
Authors: Sarici Kubra , Abraham Joseph R. , Sevgi Duriye Damla , Lunasco Leina , Srivastava Sunil K. , Whitney Jon , Cetin Hasan , Hanumanthu Annapurna , Bell Jordan M. , Reese Jamie L. , Ehlers Justis P. 
Published: January 2022

BACKGROUND AND OBJECTIVE:
To evaluate the utility of spectral-domain optical coherence tomography biomarkers to predict the development of subfoveal geographic atrophy (sfGA).

PATIENTS AND METHODS:
This was a retrospective cohort analysis including 137 individuals with dry age-related macular degeneration without sfGA with 5 years of follow-up. Multiple spectral-domain optical coherence tomography quantitative metrics were generated, including ellipsoid zone (EZ) integrity and subretinal pigment epithelium (sub-RPE) compartment features.

RESULTS:
Reduced mean EZ-RPE central subfield thickness and increased sub-RPE compartment thickness were significantly different between sfGA convertors and nonconvertors at baseline in both 2-year and 5-year sfGA risk assessment. Longitudinal change assessment showed a significantly higher degradation of EZ integrity in sfGA convertors. The predictive performance of a machine learning classification model based on 5-year and 2-year risk conversion to sfGA demonstrated an area under the receiver operating characteristic curve of 0.92 ± 0.06 and 0.96 ± 0.04, respectively.

CONCLUSIONS:
Quantitative outer retinal and sub-RPE feature assessment using a machine learning–enabled retinal segmentation platform provides multiple parameters that are associated with progression to sfGA.

[
Ophthalmic Surg Lasers Imaging
. 2022;53:31–39.]
Pain Perception of Patients Undergoing Laser Panretinal Photocoagulation: Comparison of Single-Spot Versus Multispot Techniques
Authors: Barbosa Gabriel Castilho , Silva Allan Gomes , Susanna Bianca Nicolela , Mazzeo Thiago Muniz , Bermudes Frederico Hackbart , Machado Cleide Guimarães , Gomes André Vieira 
Published: January 2022

BACKGROUND AND OBJECTIVE:
To compare pain intensity with single-spot versus multispot technique in laser panretinal photocoagulation, using a 532-nm, solid-state laser system.

MATERIALS AND METHODS:
This was a prospective, interventional, randomized, single-masked comparison trial. Patients received two types of intervention: conventional single-spot technique, with an exposure time of 150 ms, and multispot technique, done with an exposure time of 20 ms, Both techniques used power sufficient to produce visible gray-white burns, and spot size of 20 μm. Participants received both treatments in the same eye, each one in one hemiretina, and were randomized to receive first single- or multispot technique and to the initial site of treatment. We assessed pain intensity using a numerical pain scale immediately after completion of each treatment.

RESULTS:

A significantly lower pain scale was observed with the multispot when compared with the single-spot technique (coefficient [Coef]: −1.61; 95% CI, −2.49 to −0.74;
P
< .001), which was not affected by treatment order, the hemiretina treated, or treatment duration (
P
> .05). Among demographic characteristics, multiracial patients had a pain scale 1.25 greater than that of White patients (Coef: 1.25; 95% CI, 0.47 to 2.04;
P
= .002), but there is no effect of age or sex on the pain scale (
P
> .05). Regarding treatment duration, a shorter procedure was also observed in the multispot technique (Coef: −1.13; 95% CI, −1.43 to −0.82;
P
< .001), and it was not affected by order of treatment (
P
= .098), hemiretina (
P
= .327), pain (
P
= .141), or demographic data, such as age, sex, and race (
P
> .05).

CONCLUSION:
The use of the multispot technique, with a short pulse duration (20 ms), is significantly less painful and less time-consuming for patients with proliferative retinopathy compared with the conventional single-spot technique using an exposure time of 150 ms.

[
Ophthalmic Surg Lasers Imaging Retina
. 2022;53:40–45.]
Aguranabe, petite histoire des tabous alimentaires de la consommation de viande dans le Japon au milieu du XIXe siècle
Authors: Hosoi Ayame 
Published: January 2022

Dans d’innombrables ouvrages littéraires japonais, fictions et non-fictions, la description de la nourriture joue un rôle de miroir reflétant l’évolution de la société. Nous tenterons d’éclairer certaines problématiques et préoccupations populaires au Japon, à travers un ouvrage, Aguranabe (1871), de Kanagaki Robun (1829-1894). Nous pouvons observer quelques nouveautés dans les pratiques alimentaires des Japonais, concernant la viande de bœuf ou l’apparition des produits laitiers et de leurs variantes. La consommation de ces nouveaux produits présente un paradoxe intrinsèque : un sentiment de culpabilité dû à la transgression des anciens tabous alimentaires et la fierté d’être devenu « civilisé ». Dans le processus d’acculturation de cette alimentation, une notion clef, la nutrition, apparaît alors comme une justification permettant la résolution du dilemme. Ce processus met en lumière le comportement dubitatif et hésitant des Japonais face à l’inversion radicale des valeurs lors de la transition de l’ancien Japon (Edo) au Japon moderne (Meiji). Apparaît aussi une autre nouveauté, l’expression du plaisir gustatif, dont la manifestation était autrefois considérée comme impudique.
Kung food : chorégraphier les gestes culinaires
Authors: Faucon Térésa 
Published: January 2022

Ce texte s’intéresse à un sous genre des films de kung fu tournés à Hong Kong et à Shanghai depuis les années 1990, que l’on pourrait nommer « kung food », à partir de la rencontre entre la cuisine chinoise et le kung fu. Dans ces films réalisés par Tsui Hark, Stephen Chow et Wing Kin Yip de nombreux duels sont mis en scène. Les combattants doivent témoigner de qualités qui relèvent de ces deux arts : savoir couper et faire cuire les aliments, savoir voler et exprimer sa force intérieure. Il est même dit que l’académie de la cuisine chinoise n’est autre que la cuisine du Monastère de Shaolin. Ici, nous nous attachons à analyser les formes de représentation des préparations culinaires – mise en scène, découpage, montage visuel et sonore.
L’errance diagnostique en question dans les forums « maladies rares » : de la déconstruction de la figure de l’expert médical à la construction d’une expertise patient
Authors: Fèvre-Pernet Christine 
Published: January 2022

Nous observons dans notre contribution, au travers de la circulation de la parole dans les forums « Maladies Rares », comment l’errance diagnostique est vécue et perçue par les malades et comment elle remet en question le rapport au corps médical. Plus précisément, on assiste à une redistribution des rôles et à la création d’une figure d’expert (le « patient expert ») qui tire sa légitimité non plus d’un rôle social donné mais d’une somme d’expériences partagées. C’est à partir d’un corpus textuel, exploité de manière semi-automatique, que l’on s’attache à décrire comment s’opère la mise à distance de la figure de l’expert « médical » et comment se construit la communauté d’expert « patients ».
La transgression du contrat de communication dans la relation de soin en ehpad
Authors: Noda Hiroko 
Published: January 2022

Cet article vise à interroger la transgression du contrat de communication dans l’interaction de soin au sein d’Établissement d’Hébergement pour les Personnes Âgées Dépendantes (EHPAD). Les aides-soignantes (AS) sont amenées à s’ajuster à la capacité communicationnelle de chaque résident. Mais cet ajustement peut entraîner la transgression du contrat de communication. Une étude de terrain effectuée dans des EHPAD a montré que certaines AS ont employé « discrètement » des expressions affectueuses telles que ma chérie aux résidents, tout en sachant que leur emploi est interdit par l’établissement. Dans ce cas, les AS transgressent les règles en pensant au bien du résident. Par ailleurs, la transgression peut se manifester par une certaine forme de violence verbale et/ou physique. Ces cas de transgression du contrat de communication font apparaître la complexité des relations entre les AS et les résidents, ainsi que leur vulnérabilité.
Risk Factors for Hospital-Acquired Pressure Injury in Adult Critical Care Patients
Authors: Kim Phillip , Aribindi Vamsi K. , Shui Amy M. , Deshpande Sharvari S. , Rangarajan Sachin , Schorger Kaelan , Aldrich J. Matthew , Lee Hanmin 
Published: January 2022

BackgroundAccurately measuring the risk of pressure injury remains the most important step for effective prevention and intervention. Relative contributions of risk factors for the incidence of pressure injury in adult critical care patients are not well understood.ObjectiveTo develop and validate a model to identify risk factors associated with hospital-acquired pressure injuries among adult critical care patients.MethodsThis retrospective cohort study included 23 806 adult patients (28 480 encounters) with an intensive care unit stay at an academic quaternary care center. Patient encounters were randomly split (7:3) into training and validation sets. The training set was used to develop a multivariable logistic regression model using the least absolute shrinkage and selection operator method. The model’s performance was evaluated with the validation set.ResultsIndependent risk factors identified by logistic regression were length of hospital stay, preexisting diabetes, preexisting renal failure, maximum arterial carbon dioxide pressure, minimum arterial oxygen pressure, hypotension, gastrointestinal bleeding, cellulitis, and minimum Braden Scale score of 14 or less. On validation, the model differentiated between patients with and without pressure injury, with area under the receiver operating characteristic curve of 0.85, and performed better than a model with Braden Scale score alone (P &lt; .001).ConclusionsA model that identified risk factors for hospital-acquired pressure injury among adult critical care patients was developed and validated using a large data set of clinical variables. This model may aid in selecting high-risk patients for focused interventions to prevent formation of hospital-acquired pressure injuries.
Reducing root galling caused by root knot nematodes in black pepper (<em>Piper nigrum</em> L. cv. ‘Kuching’) through nutrient supplementation
Authors: Khadijah Babirye , Hung Patricia King Jie , Ismail Zahora Binti , Huat Ong Kian 
Published: January 2022

Purpose: Root-knot nematodes (RKN) remain one of the leading causes of economic damage in black pepper (Piper nigrum L.) cultivation worldwide. An experiment was conducted to evaluate the response of black pepper plants to RKN when irrigated with three nutrient solutions; Hoagland solution only, Hoagland solution + 0.005 mM potassium silicate solution, and Hoagland solution + 2 mM salicylic acid solution. Research Method: Plants grown in medium-sized polybags were inoculated with RKN and routinely irrigated with the appropriate nutrient solutions. Presence of foliar symptoms of RKN infection on plants, their aerial growth plus root infestation were assessed. Superoxide anion and hydrogen peroxide production from the plant leaves were also detected after inoculation. Findings: Foliar symptoms of RKN infection started manifesting after 81 days from inoculation. Plants without silicate or salicylic acid supplementation displayed the most severe foliar disorder symptoms, highest root galling and the shortest aerial growth. Plants irrigated with potassium silicate had the highest aerial growth and their leaves showed the least oxidative stress when challenged with RKN. Originality: From present results, soil amendment with potassium silicate is a promising tool for reducing root galling and promoting aerial growth in RKN-infested black pepper fields.
Coexistence of T-Large Granular Lymphocyte Leukemia and Peripheral T Cell Lymphoma-NOS with indolent behaviour
Authors: Guarnera Luca , Boldrini Valentina , Pasqualone Gianmario , Cimino Carolina , Meddi Elisa , Laureana Roberta , Trivigno Donata , Del Poeta Giovanni , Mauriello Alessandro , Anemona Lucia , Postorino Massimiliano , Cantonetti Maria 
Published: January 2022

T-cell lymphomas and leukemias are highly heterogeneous groups of rare disorders. We report a case of a 68-year-old man patient who develops two different T-cell neoplasms (Large Granular Lymphocyte Leukemia [LGLL] in 2018 and Peripheral T-cell non-Hodgkin lymphoma not otherwise specified [PTCL-NOS] in 2019) with a previous diagnosis of B-cell marginal zone lymphoma in 2010, treated with two lines of chemo-immunotherapy. The coexistence of these different T-cell neoplasms is rarely reported in literature and, moreover, is usually described as an LGLL transformation into PTCL-NOS; differently from these examples, herein the simultaneous conditions appear to be driven by different T-cell clones. Furthermore, the PTCL-NOS had a quite unusual behaviour, with a good disease control without intensive treatment. Because of these features, it could belong to a subgroup of indolent PTCL-NOS, not yet described in the WHO classification of T-cell neoplasms, which could benefit of less aggressive treatment.
Impact of the COVID-19 Lockdown on the Epidemiologic and Clinic Profiles of Domestic Accidents in Children
Authors: Benmassaoud Zineb , Balde Fatoumata Binta , Oudghiri Zineb , Charki Mohammed Tazi , Abdellaoui Hicham , Atarraf Karima , Afifi My Abderrahmane 
Published: January 2022

Background:
Domestic accident (DA) is any harmful accidental event that occurs suddenly in the home or its immediate surroundings. Our study aims to describe the impact of the COVID-19 lockdown in the epidemiological and clinical profiles of DAs in children and their management.

Materials and Methods:
This was a mixed descriptive study, comparing DAs occurring during the COVID-19 lockdown and the same period of the previous year. We exhaustively included all children aged from 0 to 15 years admitted for DAs.

Results:
The incidence of DAs remains above 50% in both groups. The average age was 7 years and boys were more affected. Before the COVID-19 lockdown, the most common mechanism encountered was accidents on the public highway 20.75%, while during the lockdown, it was represented by falls from a high place with a height of 2 m or more. During the lockdown, 33.86% of patients consulted after more than 24 h of the trauma. Supracondylar fractures and burns remained the most frequent. In all cases, the cumulative frequency of fractures decreased during the lockdown. The COVID-19 lockdown had no impact on patient's management.

Conclusion:
The COVID-19 lockdown has negatively increased the consultation delay. However, it has considerably reduced the incidence of fractures.
Serum level of Total Antioxidant Status and Malondialdehyde in the Patients with Polycystic Ovarian Syndrome: a Comparative Study
Authors: Magar Bibek Pun , Pun Magar Dilli , Amgain Kapil , Joshi Keshavraj , Satyal Niranjan , Oli Jharendra Bahadur 
Published: January 2022

Background: Polycystic ovary syndrome (PCOS) is a complex endocrine disorder in women of reproductive age and a major cause of infertility. Anti- Mullerian Hormone (AMH), a valid marker of ovarian function, is used for the diagnosis of PCOS. The aim of this study is to assess the serum level of total antioxidant status (TAS) and malondialdehyde (MDA) in the premenopausal women with PCOS.
Methods: A cross-sectional analytical study was conducted at Padmashree Diagnostics, Department of Gynecology, India from April 2016 to March 2017. Census method was used to select the samples. The oxidative stress was measured by measuring the level of TAS and MDA. The data was recorded in structured proforma and and enter in SPSS version 16.0. The data were expressed in frequency, percentage, mean and standard deviation and the results obtained were analyzed using pearson’s correlation and student’s t-test. The p-value less than 0.05 was taken as statistically significant.
Results: The measured serum AMH level among the patients with PCOS was within normal range in 67.5% (27) and above normal range in 32.5% (13). The serum TAS level in normal AMH group was 814.0 + 291 µMol/L and in above normal range group was 720 + 240 µMol/L, (p <0.001). Similarly, the serum level of MDA in normal AMH group was 6.64 + 0.21 µMol/L, and in above normal range group was 8.78 + 0.22 µMol/L (p = 0.01). The measured level of AMH was significantly associated with the increased level of MDA (p<0.001) and decreased level of TAS (p<0.001). The measured MDA level in high AMH group did show statistically significant than the normal AMH group.
Conclusions: Serum level of TAS and MDA along with AMH are valuable diagnostic biomarker for the diagnosis of PCOS in the resource poor settings where ultrasound facility is unavailable.
Peran Media Massa Terhadap Partisipasi Politik Mahasiswa Pada Pemilihan Umum 2019
Authors: Intyaswati Drina 
Published: January 2022

Pada era media berbasis internet saat ini, diperlukan telaah terhadap peran media massa konvensional sebagai sumber informasi politik dan kontribusinya pada partisipasi politik kalangan muda. Studi ini bertujuan melihat pengaruh penggunaan media massa konvensional, yaitu televisi, radio dan suratkabar pada partisipasi politik di kalangan mahasiswa. Sampel sebanyak 400 mahasiswa diperoleh melalui metode survei dengan menggunakan kuisioner. Mahasiswa berasal dari UPNVJ Jakarta jurusan Ilmu Komunikasi. Hasil menunjukkan bahwa penggunaan televisi dan surat kabar secara signifikan berpengaruh terhadap partisipasi politik mahasiswa. Akan tetapi terdapat hubungan negatif antara penggunaan televisi dan partisipasi politik. Semakin sering mahasiswa menonton televisi terkait informasi politik, terdapat kecenderungan berkurangnya tingkat partisipasi politik. Diperlukan studi selanjutnya untuk dapat lebih menjelaskan temuan tersebut. Selain itu ditemukan rendahnya tingkat partisipasi politik di kalangan mahasiswa
Pharmacy education shift during times of pandemic and collapse: A perspective from a school of pharmacy in Lebanon
Authors: Hammoudi Halat Dalal , Safwan Jihan , Akel Marwan , Rahal Mohamad 
Published: January 2022

Introduction: The health and economic crisis in Lebanon during the COVID-19 pandemic has had detrimental effects on many sectors including higher education. This report presents the major changes in teaching/learning undertaken by three departments of the bachelor programme in a school of pharmacy in Lebanon to cope with uncertain times.
Description: The educational process was modified from autumn 2019/20 to spring 2020/21, with economical instabilities and the emergence of COVID-19, where regular teaching and summative assessments were completely and forcefully switched to remote and online.
Evaluation: Although a grade trend showed some changes in evaluation with the crisis, grades returned nearly to normal upon adopting the completely online system. Technical support and training for the faculty were required to help cross transitioning periods and maintain the quality of the programme.
Conclusion: The crisis and the pandemic influenced pharmacy education, but gave students and faculty the chance to learn and utilise modern information and communication technology (ICT) educational tools.
Potensi Vermisidal Infusa Biji Buah Merah (Pandanus conoideus), Rumput Kebar (Biophytum petersianum) dan Kulit Buah Pinang (Areca catechu) terhadap Ascaridia galli secara In Vitro
Authors: Arizona Rizki , Nurhayati Dwi , Ollong Abdul R. , Sambodo Priyo 
Published: January 2022

Abstract
This study aimed to determine the vermicidal potency of the infusion of Buah Merah seeds, Rumput Kebar and betel nut peels against Ascaridia galli in chickens and body length of male and female A. galli. Dry test materials (5%, 10% and 15% for each concentration) were immersed in 100 ml of distilled water and incubated at 90 °C for 15 minutes. The solution was filtered using filter paper, and the filtrate was used in the treatment. Three active worms that obtained directly from chicken intestines were placed in 15 cm Petri dishes containing 25 ml of each treatment and control solution. Five replications were performed for each treatment. Observations were made 8 hours after treatment for paralysis and worm death. Measurements of the body length were made from the anterior end to the posterior end of the worm using a ruler. Observational data were processed using Anova, the significant difference was continued by the Tukey HSD test (P<0.05) with SPSS 16.0. Conclusion: all the materials used in this study have potential as anthelmintics against A. galli and the highest dose of rumput Kebar infusion is the best vermicidal. The body length of female A. galli is longer than of the male.
Keywords: Betel nut peels; Buah merah seeds; Infusion; Rumput kebar; Vermicidal

Abstrak
Penelitian ini bertujuan untuk mengetahui potensi vermisidal infusa biji Buah Merah, Rumput Kebar dan kulit buah Pinang terhadap Ascaridia galli pada ayam dan ukuran panjang tubuh A. galli jantan dan betina. Bahan uji kering (5%, 10% dan 15% untuk masing-masing konsentrasi) direndam dalam 100 ml aquadestillata dan diinkubasi pada suhu 90 °C selama 15 menit. Larutan disaring menggunakan kertas saring, dan filtratnya digunakan dalam perlakuan. Tiga cacing yang aktif bergerak yang diperoleh langsung dari usus ayam, ditempatkan dalam cawan Petri berukuran 15 cm yang berisi 25 ml masing-masing larutan perlakuan dan kontrol. Dilakukan lima ulangan untuk setiap perlakuan. Pengamatan dilakukan 8 jam setelah perlakuan terhadap paralisis dan kematian cacing. Pengukuran dilakukan dari ujung anterior ke ujung posterior cacing menggunakan penggaris. Data hasil pengamatan diolah menggunakan Anova, perbedaan nyata dilanjutkan dengan uji Tukey HSD (P<0,05) dengan SPSS 16.0. Kesimpulan: seluruh bahan yang digunakan pada penelitian ini memiliki potensi sebagai anthelmintik terhadap A. galli dan dosis tertinggi infusa rumput Kebar merupakan vermisidal yang paling baik. Panjang tubuh A. galli betina lebih panjang dari pada jantan.
Kata kunci: Biji buah merah; Infusa; Kulit buah pinang; Rumput kebar; Vermisidal
The Effectiveness of Problem Based Learning (PBL) Based Socioscientific Issue (SSI) to Improve Critical Thinking Skills
Authors: Fita Muflichatu Nur , Jatmiko Budi , Sudibyo Elok 
Published: January 2022

The purpose of this research was to see how effective the Problem Based Learning (PBL) based Socioscientific Issues (SSI) is at improving critical thinking skills. The sample used was grade seven in SMPN 4 Lamongan with 2 classes and each class contains 15 students. The design of the learning materials trial used One-Group pre-test post-test design. Tests of critical thinking skills and student answer sheets were used to collect data. Techniques of data analysis used N-gain, paired t-test, and independent t-test. The result of this research is as follows: The effectiveness in terms of the critical thinking skills test the category increase is high, there is a significant difference between the test before and after learning with PBL based SSI and there is no difference N-gain in the two group classes and students' responses are classified as very good. Based on data analysis, it can be concluded that PBL with SSI is effective to improve critical thinking skills. The implications of this study are PBL-based SSI has the potential to be an innovative solution and alternative for improving critical thinking skills.