bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFFECT OF ARTERIAL HYPERTENSION ON LEFT VENTRICULAR GEOMETRIC REMODELING AND LEFT ATRIAL MECHANICAL DYSFUNCTION IN ATRIAL FIBRILLATION
Authors: Dotsenko M. Ya. , Boev S. S. , Molodan O. V. , Gerasimenko L. V. , Shehunova I. O. , Malinovska O. Ya. 
Published: June 2022

Summary. Purpose: to study changes in the structural and functional parameters of the left atrium and left ventricle in patients with arterial hypertension and atrial fibrillation.
Material and methods. The study involved 52 patients with stage II-III arterial hypertension, which were divided into 2 groups depending on the presence or absence of atrial fibrillation. The first group included 21 patients with arterial hypertension without atrial fibrillation, the second group included 31 patients with arterial hypertension with atrial fibrillation. Transthoracic echocardiography was performed using an Acuson X 700 Siemens ultrasound system.
Results. All patients had an increased mass index of the left ventricular myocardium. With atrial fibrillation, concentric hypertrophy was noted in 22 (71%) and eccentric hypertrophy in 9 (29%) patients; and without arrhythmia in 17 (81%) and 4 (19%), respectively. In the second group of patients, there was an increase in mean pressure in the left atrium and the presence of type 3 diastolic dysfunction of the left ventricle.
Left ventricular hypertrophy increases the stiffness of the left ventricle, which is confirmed in our study by an increase in the decrease in the longitudinal S of the left ventricle in atrial fibrillation in relation to patients without it.
There was a significant decrease in the indicator of left atrial deformation in patients with atrial fibrillation compared with patients without arrhythmia (15.9±2.4% and 26.9±4.1%, respectively (p≤0.05)) with a sharp decrease in stool fraction left atrium (15.1±4.1 and 35.0±5.2, respectively (p≤0.05)).
Conclusion. In patients with arterial hypertension with atrial fibrillation, there is a change in the remodeling of the left ventricle and atrium, and the deformation and emptying fraction of the left atrium is greater than the increase in its volume.
CORRECTION OF SOME SIDE EFFECTS TO ANTI-TUBERCULOSIS THERAPY IN MODERN CONDITIONS
Authors: Prosvetov Yu. V. , Gusarova A. Yu. , Barinov S. S. , Husarova A. V. 
Published: June 2022

Introduction. Tuberculosis has not been eradicated in any country in the world. Chemotherapy plays a leading role in this fight. In the last two decades, the level of chemoresistant tuberculosis has increased significantly, contributing to an increase in the total number of side effects, often severe and widespread.
The aim of the study. Improving the effectiveness of treatment and quality of life of TB patients. This is based on scientific substantiation and development of methods for drug correction of toxic side effects of anti-TB therapy.
Materials and methods. 818 cases of complications from the use of anti-TB therapy were analyzed among patients treated at Zaporizhzhia Regional Clinical TB Dispensary between 2012 and 2016. Side effects increased over these years, due to an increased attention to pharmacovigilance.
Results. During the treatment of patients with pulmonary TB with preserved sensitivity to anti-TB therapy, side effects occurred in 48.8% of cases and in chemoresistant forms 51.2%. Patients with resistant forms of the process which were assigned to the 4th category of treatment predominated with complications of anti-TB therapy. Their percentage was 55.1%, which was 10.2% more than patients with preserved sensitivity. The structure of side effects was dominated by hepatotoxic reactions (36.0%) which were most often (28.0%) associated with the use of pyrazinamide and later returned to normal from the use of ademethionine. In total, the use of pyrazinamide resulted in 40.4% of cases of side effects.
Conclusions. The course of ademethionine helps to normalize clinical and laboratory parameters, regression of symptoms of toxic liver disease and improves the quality of life of patients with chemoresistant tuberculosis with toxic side effects of anti-TB therapy, which significantly reduces the length of hospital stay and increases treatment efficiency with compliance.
Web-Based Employee Work Scheduling Information System Design at PT Trafoindo Power Indonesia
Authors: Setiadi Ade , Effendy Yusuf , Hidayat Nur Rahmat , Syamsi Nur , Rachellya Lintang Gadis Ratu 
Published: June 2022

This study aims to assist PT Trafoindo Power Indonesia in improving the description of the employee work scheduling website. So far, several departments of PT Trafoindo Power Indonesia use an application called Microsoft Excel to process employee work schedules and save a file on a public server where each employee has access to open and perform data engineering. The solution to the indication of the problem is to create a new system design that functions to process data in the form of employee work schedules with a one-way input system. The website is one of the choices that companies need if they want to present information both internal and external. A website would be better if there is a database or what is commonly known as a data warehouse, for the basis of reference for decision-makers tomorrow.
In this case, the design of an employee work scheduling information system using Bootstrap as its platform. To obtain the data needed in conducting research, several methods were used, including interviews, observation, and literature study. The data obtained were then analyzed and described using the UML (Unified Modeling Language) method. The final result of the research is the design of a Bootstrap-based employee work scheduling information system using Visual Studio Code as the code editor.
Impact of An Instructional Program on Hypothyroidism Patients’ Knowledge Toward Physical Exercise and Activity Daily Livings
Authors: AL Aqeeli Mohammed , Hassan Hakima 
Published: June 2022

ABSTRACT:
Background: The effect of physical exercise on hypothyroidism exists argumentative and require more ferrets. Poor knowledge of the patients with hypothyroidism regarding physical exercise and Activity Daily Livings (ADLs) can change in their lifestyle, deteriorate symptoms and complications.
Objective: The main objective of the present research is to evaluate the effectiveness of an instructional program on hypothyroidism patients’ knowledge toward physical exercise and ADLs.
Methodology: one group study (pretest– posttest) a pre experimental design study was used to conduct this study at Baghdad teaching hospitals from 2th March, 2021 to 30th Jun, 2021. A purposive sampling non probability was applied to select 50 patients with hypothyroidism were coming to Baghdad teaching hospitals. The validity of the questionnaire was verified by 20 experts. The reliability was determined the knowledge questionnaire by using (test and retest) approach. Statistics were used to analyze the results of the study using (SPSS) version (22).
Results: Statistically significant differences found between the scores of the patients’ knowledge in two levels of measurements (pre- test and post-test) at (p<0.01), where the statistical global mean of score (GMS) for knowledge of patients regarding the physical exercise in pre-test was (0.195), while GMS .
becomes (0.880) in post-test. Furthermore, there is no relationship among age, gender and level of education variables and hypothyroidism patients’ knowledge toward physical exercise and ADLs at (p>0.05) in pre and posttest.
Conclusion: Poor knowledge of hypothyroidism patients’ toward physical exercise and Activity Daily Livings (ADLs) in (pretest) and clear improvement in their knowledge of the patients after applying the instructional program in (posttest) and there is no relationship between Socio- Demographic variables(Age, Gender and Level of education) with knowledge of hypothyroidism patients’ regard to physical exercise and ADLs.
Recommendations: The study recommends conduct further large cross- sectional studies on big populations to develop the knowledge of the patients and achieving the well-being of the society.
Keywords: Instructional program, Hypothyroidism, Knowledge, Exercise, Activity Daily Livings.
Impact of Implementing Revenue Recognition Based on Psak 72 in the COVID-19 Pandemic Period
Authors: Saputri Mashuri Ayunita Ajengtiyas , Dyah Pita Sari Ratna Hindria 
Published: June 2022

This study was conducted to determine the effect of the application of PSAK 72 as well know as Revenue from contracts with customers. Financial performance using profitability ratios, which is proxied by Return on Assets. In this study, financial performance variables are used to find out more about companies implementing PSAK 72 during the covid 19 pandemic. The objects in this study are companies in the retail, telecommunications, real estate and contractor sectors listed in the IDX-Industrial Classification. The sample was selected using a purposive sampling technique so that the sample obtained was 127 samples during 2020 solely. The software or tool used to test the hypothesis is SPSS version 26. The results of this study result is There is no effect of the application of PSAK 72 in financial performance as measured by profitability ratios. although the implementation of PSAK 72 shows no significant (negative) effect, however, the company has made efforts to prepare for the implementation of PSAK 72 in 2019 by organizing training for its employees and evaluations before finally implementing PSAK 72. Thus, that the implementation of 72 does not have a completely have no on the company's financial performance, this is because the implementation PSAK 72 coincided with the Covid-19 pandemic which also caused the company's revenue to decrease.
ВІДНОВЛЕННЯ ДЕТАЛЕЙ КЛАПАНА КЕРУВАННЯ ПАЛИВНИХ ФОРСУНОК BOSCH З ПЄЗОЕЛЕКТРИЧНИМ ПРИВОДОМ
Authors: КИЩУН Володимир 
Published: June 2022

Параметри паливної форсунки із п’єзоелектричним приводом залежить від розпилювача і клапана керування, технічний стан яких суттєво впливає на економічні та екологічні показники роботи двигуна. У випадку виходу з ладу цих прецизійних пар, фірма BOSCH рекомендує заміну цілої форсунки, а це підвищує вартість ремонту.
Практика експлуатації показує, що першочергово руйнуються голка і корпус розпилювача та клапан керування. Виходячи з аналізу виду пошкоджень, сервісні центри ухвалюють рішення стосовно способу повернення параметрів форсунки до нормативних. Зокрема, якщо погіршення роботи форсунки викликане зношенням контактних поверхонь голки і корпуса розпилювача, то проводилася реставрація цих деталей.
Натомість, технологія відновлення клапанів керування форсунок BOSCH не завжди відповідає заводській, оскільки потребує спеціального обладнання, тому станції з ремонту паливної апаратури, кожна своїми методами, проводять реставрацію фірмових форсунок. Зазвичай, використовується процес взаємного притирання штока клапана до сідла, що може навпаки вивести форсунку з ладу.
У статті пропонується технологія відновлення роботоздатності клапана керування паливних форсунок BOSCH із п’єзоелектричним приводом, яка на практиці підтвердила свою ефективність. Процес відновлення спряжених поверхонь клапана керування відбувається поетапно. На першому етапі проводиться перешліфування обох конусів штока клапана. З цією метою був розроблений комплекс, основою якого став спеціально спроектований і виготовлений пристрій для перешліфування. На другому етапі методом притирання на універсальному притирочному станку МР-250 відновлюється поверхня сідла клапана. Заключний етап – це шліфування поверхні прилягання сідла клапана до дроселюючої пластини.
Запропонована технологія відновлення клапана керування паливних форсунок фірми BOSCH із п’єзоелектричним приводом дозволяє продовжити їх експлуатацію із збереженням технічних і економічних показників роботи та зекономити кошти на ремонті.
Ключові слова: п’єзофорсунка BOSCH, клапан керування, шток і сідло клапана, спряжені поверхні, технологія відновлення.
texto multimodal y sus usos en la educación primaria
Authors: Calderón Núñez Valentina 
Published: June 2022

El objetivo principal de esta investigación es conocer el uso del texto multimodal en el ámbito educativo, ya sea para su enseñanza o su producción en el aula. Con este fin el estudio se efectúa a través de una revisión sistemática de literatura especializada mediante análisis basados en dos categorías, la metodológica y de resultados. La primera categoría revisa y analiza las inclinaciones de los artículos hacia el uso de metodologías cualitativas, tendencia a instrumentos como el diario de campo y la preferencia por los análisis de tipo categórico y estadístico. Respecto de la segunda, constata tendencias a partir de los resultados de cada investigación, plasmando las limitaciones de la enseñanza del texto multimodal y la producción de textos multimodales que fomentan el desarrollo de habilidades. A raíz de esto, se concluye revisando los factores que están presentes en la aplicación de los textos multimodales, y se consideran tanto sus limitaciones como su contribución en el proceso de aprendizaje del alumnado.
RR Lyrae-based Distances for 39 Nearby Dwarf Galaxies Calibrated to Gaia eDR3
Authors: Nagarajan Pranav , Weisz Daniel R. , El-Badry Kareem 
Published: June 2022

Abstract
We provide uniform RR Lyrae-based distances to 39 dwarf galaxies in and around the Local Group. We determine distances based on a Bayesian hierarchical model that uses periods and magnitudes of published RR Lyrae in dwarf galaxies and is anchored to well-studied Milky Way (MW) RR Lyrae with spectroscopic metallicities and Gaia eDR3 parallaxes. Gaia eDR3 parallaxes for the anchor sample are a factor of 2, on average, more precise than DR2 parallaxes, and allow for a much better constrained period–luminosity–metallicity relation. While ∼75% of our distances are within 1σ of recent RR Lyrae distances in the literature, our distances are also ∼2–3 times more precise than distances in the literature, on average. On average, our distances are ∼0.05 mag closer than distances in the literature, as well as ∼0.06 mag closer than distances derived using a theoretical period–luminosity–metallicity relation. These discrepancies are largely due to our eDR3 parallax anchor. We show that the Hipparcos-anchored RR Lyrae distance scale of Carretta et al. overpredicts distances to MW RR Lyrae by ∼0.05 mag. The largest uncertainties in our distances are (i) the lack of direct metallicity measurements for RR Lyrae and (ii) the heterogeneity of published RR Lyrae photometry. We provide simple formulae to place new dwarf galaxies with RR Lyrae on a common distance scale with this work. We provide a public code that can easily incorporate additional galaxies and data from future surveys, providing a versatile framework for the cartography of the local universe with RR Lyrae.
Atmospheric Circulation in Simulations of the AGN–CGM Connection at Halo Masses ∼1013.5
M
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Authors: Prasad Deovrat , Voit G. Mark , O’Shea Brian W. 
Published: June 2022

Abstract
Coupling between active galactic nuclei (AGNs) and the circumgalactic medium (CGM) is critical to the interplay between radiative cooling and feedback heating in the atmospheres of the universe’s most massive galaxies. This paper presents a detailed analysis of numerical simulations showing how kinetic AGN feedback with a strong momentum flux interacts with the CGM. Our analysis shows that large-scale CGM circulation driven by that momentum flux plays an important role in reconfiguring the galactic atmosphere and regulating the atmosphere’s central entropy level. We find that most of the AGN's energy output goes into lifting of circumgalactic gas rather than heating of atmospheric gas within the galaxy, consequently reconfiguring the CGM by replacing low-entropy gas originally in the core with higher-entropy gas from larger radii. Circulation of the CGM on ∼10–100 kpc scales therefore plays a critical role in preventing overcooling of gas in these simulated galaxies, but leads to elevated entropy profiles ∼1–10 kpc compared to the observed entropy profiles of massive elliptical galaxies in the same mass range. The simulations also show that our choices of accretion efficiency and jet opening angle significantly affect the AGN–CGM coupling. Reducing the jet opening angle to one-quarter of the fiducial opening angle increases the jet momentum flux, enabling it to drill through to larger radii without effectively coupling with the CGM at the center (r < 5 kpc). Outflows with a lower momentum flux decelerate and thermalize the bulk of their energy at smaller radii (r ≲ 10 kpc).
Escherichia coli Clonal Variability Based on Genetic Diversity Pattern with Enterobacterial Repetitive Intergenic Consensus-Polymerase Chain Reaction Methods for Traveler’s Diarrhea Cases in Bali
Authors: Sukrama I Dewa Made , Pinatih Komang Januartha Putra , Hendrayana Made Agus , Rasyid Burhannuddin , Wedari Ni Luh Putu Harta 
Published: June 2022

BACKGROUND: Bali is a favorite tourism destination in the world. As a major tourist destination, the incidence of illness that afflicts tourists greatly affects the image of tourism. Diarrhea is a health problem that is most often experienced and is a major obstacle for foreign tourists when traveling, especially to Bali. Escherichia coli (E. coli) bacteria cause diarrhea more often than viruses in some developing countries. Genetic differences can affect the characteristics of E. coli, especially in relation to the medical field.

AIM: We would like to assess the genetic diversity of the different pathogenic E. coli from various clinical isolates including those from traveler’s diarrhea in Bali, Indonesia.

MATERIALS AND METHODS: One of the molecular techniques used in this study is to use enterobacterial repetitive intergenic consensus-polymerase chain reaction (ERIC-PCR). The sample in this study was the feces of foreign tourists with traveler’s diarrhea in Bali. This study carried out research procedures in the form of Isolation of E. coli genome DNA from culture, amplification of E. coli 16S rRNA encoding genes, sequencing of E. coli 16S rRNA encoding genes, phylogenetic tree construction, and then analysis of E. coli genetic diversity with ERIC-PCR sequences.

RESULTS: The results showed that the ERIC-PCR method was more discriminatory than other methods to analyze the genetic diversity of E. coli from fecal samples of patients with traveler’s diarrhea. It was found that clonal variability based on the genetic similarity of all sample E. coli isolates varied from 0% to 100%.

CONCLUSIONS: This shows that the source of transmission and the strains of E. coli that cause it comes from diverse populations.
Antidepressant Activity of Curcuma heyneana
Authors: Marianne Marianne , Hasibuan Poppy Anjelisa , Bin Emran Talha , Ramadhayani Sartika , Nasution Rosnani , Bastian Reza Akbar 
Published: June 2022

BACKGROUND: The resistance to depression therapy remains high, and therapy failure leads to suicide. Curcuma heyneana (C. heyneana) is a plant of Zingiberaceae. Conventionally, the rhizome has been used as an anxiolytic and sedative. However, the activity as antidepression has never been conducted.

AIM: Therefore, this research was aimed to investigate the antidepressant activity of C. heyneana rhizome.

METHODS: This research was conducted using male mice aged 2–3 months. Chronic mild stress for 14 days was used to induce depression, followed by administration of the extract at 50, 100, and 200 mg/kg for 10 days. Evaluation of antidepression was carried out using tail suspension test (TST), forced swim test (FST), open field test (OFT), and blood glucose and injury of gastric. Sertraline at the dose of 6.5 mg/kg was used as a positive control.

RESULTS: The result revealed that stress induction for 14 days causes decreasing in locomotor activity and increased immobility. The extract administration at the doses of 100 and 200 mg/kg showed increased locomotor activity, which can be seen from the elevation of the central square and cross in the OFT (p < 0.05). The extract also decreased immobility in the tail suspension and FSTs (p < 0.05). Furthermore, the extract also prevents increases in blood glucose and gastric irritation.

CONCLUSION: Extract of C. heyneana rhizome at the doses of 100 and 200 mg/kg has antidepressant activity by increasing locomotor activity, decreasing immobility time, and preventing elevation of blood glucose and gastric injury.
Célébrités transimpériales. Sur les routes des premières stars de la guitare katangaise dans les années 1950
Authors: Grabli Charlotte 
Published: June 2022

Cet article examine l’émergence de la célébrité musicale africaine dans le contexte du développement de la radio, de l’industrie du disque et de l’ethnomusicologie après 1945. Il explore la notion de « célébrité transimpériale » du point de vue des guitaristes Jean Bosco Mwenda et Édouard Masengo, devenus les premières stars de l’est du Congo belge et deux des artistes les plus mobiles du continent dans les années 1950. Originaires du Katanga, une région au carrefour des influences musicales de Léopoldville (Kinshasa) et de Johannesburg, ces guitaristes ont investi et ouvert de nouveaux circuits musicaux au Congo, en Afrique du Sud et au Kenya. L’article retrace leurs « territoires circulatoires » en combinant l’étude de leur mobilité spatiale et sociale, pour éclairer un pan méconnu de l’histoire sociale et culturelle de cet espace transimpérial. Il montre ainsi comment les débuts de la célébrité médiatique prolongeaient les routes de musiciens populaires dont le mode de vie reposait sur une ancienne culture de l’itinérance.
La genèse du bloc de constitutionnalité
Authors: Denizeau-Lahaye Charlotte 
Published: June 2022

Aucune expression doctrinale n’a connu, en droit constitutionnel français, autant de succès que l’expression « bloc de constitutionnalité ». Depuis près de cinquante ans et sans jamais être utilisée par le Conseil constitutionnel, elle s’est imposée, comme une formule évidente, rassurante et commode pour désigner, sous un mot pratique et imagé, l’ensemble des normes utilisées par le Conseil pour effectuer son contrôle de constitutionnalité. Réfléchir à la genèse du bloc invite à se pencher sur la naissance de l’expression, sur le choix du mot « bloc », dont les vertus fédératrices et pédagogiques ne compensent pas pleinement son inaptitude à rendre compte de l’hétérogénéité et des failles de l’édifice. Au-delà de cette question sémantique, il importe de comprendre pourquoi au début des années 1970, le Conseil constitutionnel a ressenti la nécessité urgente pour la France de se doter de son propre catalogue de droits et libertés fondamentaux, qui allait désormais être opposé au législateur.