bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sleep quality and associated factors among nurses working at comprehensive specialized hospitals in Northwest, Ethiopia
Authors: Segon Tesfaye , Kerebih Habtamu , Gashawu Fanuel , Tesfaye Bizuneh , Nakie Girum , Anbesaw Tamrat 
Published: August 2022

BackgroundPoor sleep quality is common among nurses. This problem possibly results in negative emotional and psychological consequences in nurses which secondary affect their work performances. However, in Ethiopia, there is a paucity of information about poor sleep quality and associated factors among nurses. This study aimed to assess the prevalence of poor sleep quality and associated factors among nurses working at comprehensive specialized hospitals in Northwest Ethiopia.MethodsAn institutional-based cross-sectional study was conducted among 542 nurses who worked at University of Gondar (UOG), Tibebe Ghion, Felege Hiwot Comprehensive Specialized Hospitals, Ethiopia, who were incorporated into the study through a simple random sampling technique from 1 May to 2 June 2021. The Pittsburgh sleep quality index (PSQI) with a cut score of above 5 was used to assess sleep quality using a structured self-administered questionnaire. Other tools used are Depression Anxiety Stress Scales (DASS-21), Shift Work sleep disorders (SWSD), and Oslo-3 social support scales. Epi-Data version 3.1 was used for data entry and SPSS version 25 was used for data analysis. A multivariable logistic regression analysis was performed to identify variables that have a significant association with poor sleep quality among nurse professionals. The degree of association was assessed using an odds ratio (OR) with a 95% confidence interval (CI) at a two-tailedp-value of &lt;0.05.ResultsA total of 510 nurses were included in the study with a response rate of 94%. The study showed that the overall prevalence of poor sleep quality among nurses was 75.5% (95% CI (71.8, 79.1). Being female (AOR = 1.72:95% CI = 1.19, 2.28), depressive symptoms (AOR = 2.24:95% CI = 1.24, 3.85), anxiety symptoms (AOR = 2.12: 95% CI = 1.23, 3.62), stress (AOR = 2.85: 95% CI = 1.67, 4.82) and current alcohol drinking (AOR = 1.84 :95% CI = 1.27, 3.13) were significantly associated with poor sleep quality.ConclusionThe overall prevalence of poor sleep quality among nurses was high. Being female, depressive symptoms, anxiety symptoms, stress, and current alcohol drinking had been significantly associated with poor sleep quality. Therefore, it is essential to institute effective intervention strategies emphasizing contributing factors to poor sleep quality.
The relationship between TLR4/NF-κB/IL-1β signaling, cognitive impairment, and white-matter integrity in patients with stable chronic schizophrenia
Authors: Li Hongna , Chen Wenjin , Gou Mengzhuang , Li Wei , Tong Jinghui , Zhou Yanfang , Xie Ting , Yu Ting , Feng Wei , Li Yanli , Chen Song , Tian Baopeng , Tan Shuping , Wang Zhiren , Pan Shujuan , Li Na , Luo Xingguang , Zhang Ping , Huang Junchao , Tian Li , Li Chiang-Shan R. , Tan Yunlong 
Published: August 2022

ObjectivePrevious studies have implicated intricate interactions between innate immunity and the brain in schizophrenia. Monocytic Toll-like receptor (TLR) 4 signaling, a crucial “sensor” of innate immunity, was reported to be over-activated in link with cognitive impairment in schizophrenia. As TLR4 is predominantly expressed on gliocytes prior to expression in neurons, we hypothesized that higher TLR4 levels may contribute to cognitive deterioration by affecting white matter microstructure.MethodsForty-four patients with stable chronic schizophrenia (SCS) and 59 healthy controls (HCs) were recruited in this study. The monocytic function was detected with lipopolysaccharide (LPS) stimulation to simulate bacterial infection. Basal and LPS- stimulated levels of TLR4, nuclear factor-kappa B (NF-κB), and interleukin (IL)-1β were quantified with flow cytometry. Cognitive function was assessed by the MATRICS Consensus Cognitive Battery (MCCB) and psychopathological symptoms were evaluated by the Positive and Negative Syndrome Scale (PANSS). We employed diffusion tensor imaging with a 3-T scanner and evaluated white-matter integrity with fractional anisotropy (FA). Subcortical volume and cortical thickness were also assessed.ResultsThe TLR4/NF-κB/IL-1β signaling pathway was activated in patients with SCS, but responded sluggishly to LPS stimulation when compared with HCs. Furthermore, monocytic TLR4 expressions were inversely correlated with cognitive function and white matter FA, but not with cortical thickness or subcortical gray matter volume in schizophrenia.ConclusionOur findings support altered TLR4 signaling pathway activity in association with deficits in cognition and white matter integrity in schizophrenia.
Early childhood caries prevalence and associated factors among preschoolers aged 3–5 years in Xiangyun, China: A cross-sectional study
Authors: Liu Mingshan , Song Qianqian , Xu Xiaoqin , Lai Guangyun 
Published: August 2022

PurposeThis study aimed to investigate the early childhood caries (ECC) prevalence among preschoolers aged 3-5 years in Xiangyun of Yunnan, China and explore the factors associated with the prevalence.Materials and methodsA cross-sectional survey including 3-5-year-old children was conducted in Xiangyun County, China, between September and November 2020. According to the dental examination standard of the WHO 2013 criteria, the presence of ECC was recorded. Besides the dental examination for children, their parents completed questionnaires about caries-related factors, including demographic variables, family socioeconomic status, feeding, and oral health-related habits, parental dental knowledge, and the condition of dental service utilization. SPSS Statistics 25.0 (IBM, Chicago, IL, USA) was used for data analysis. Statistical significance was set at p &lt; 0.05.ResultsThe ECC prevalence among a sample of 1,280 children aged 3–5 years consisting of 665 boys and 615 girls in this study, was 74.3%, and the mean decayed-missing-filled teeth (dmft) was 4.9 ± 5.0. There were no statistically significant differences in the ECC prevalence between the sexes and among different ethnic groups. Children with different dietary and oral hygiene habits showed no significantly different prevalence of ECC. Logistic regression analysis showed that the most significantly associated factors were older age, lower family income, and worse parental perception of children's oral health status.ConclusionThe ECC prevalence among 3–5-year-old preschool children in Xiangyun was higher than the average national ECC prevalence in China. This study implies that more attention should be given to children's caries prevention from early childhood; oral health education and promotion should be intensified to reduce the ECC prevalence and improve the oral health status of children in Xiangyun.
Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid
Authors: Sathyasaikumar Korrapati V. , Notarangelo Francesca M. , Kelly Deanna L. , Rowland Laura M. , Hare Stephanie M. , Chen Shuo , Mo Chen , Buchanan Robert W. , Schwarcz Robert 
Published: August 2022

The pivotal tryptophan (TRP) metabolite kynurenine is converted to several neuroactive compounds, including kynurenic acid (KYNA), which is elevated in the brain and cerebrospinal fluid of people with schizophrenia (SZ) and may contribute to cognitive abnormalities in patients. A small proportion of TRP is metabolized to serotonin and further to 5-hydroxyindoleacetic acid (5-HIAA). Notably, KP metabolism is readily affected by immune stimulation. Here, we assessed the acute effects of an oral TRP challenge (6 g) on peripheral concentrations of kynurenine, KYNA and 5-HIAA, as well as the cytokines interferon-γ, TNF-α and interleukin-6, in 22 participants with SZ and 16 healthy controls (HCs) using a double-blind, placebo-controlled, crossover design. TRP raised the levels of kynurenine, KYNA and 5-HIAA in a time-dependent manner, causing >20-fold, >130-fold and 1.5-fold increases in kynurenine, KYNA and 5-HIAA concentrations, respectively, after 240 min. According to multivariate analyses, neither baseline levels nor the stimulating effects of TRP differed between participants with SZ and HC. Basal cytokine levels did not vary between groups, and remained unaffected by TRP. Although unlikely to be useful diagnostically, measurements of circulating metabolites following an acute TRP challenge may be informative for assessing the in vivo efficacy of drugs that modulate the neosynthesis of KYNA and other products of TRP degradation.
Impact of IFRS 9 in Light of Uncertainty Caused by Corona Pandemic
Authors: Rashwan Abdul Rahman Mohammed , Shaqfa Khalil Ibrahim 
Published: August 2022

This study aimed to highlight the impact of the application of the International Financial Instrumentation Standard (IFRS 9) in light of the uncertainty caused by the Corona pandemic.
The results of the study concluded that IFRS 9 contributes to determining the expected credit losses that need to be recognized under the Corona pandemic in Palestinian banks listed in the Palestine Stock Exchange and that Palestinian banks listed in the Palestine Stock Exchange are working to prove the expected credit losses of financial instruments when credit risk increases in accordance with the requirements of the International Accounting Standard (IFRS 9). The researchers recommended that Palestinian banks listed in the Palestine Stock Exchange should further disclose financial instruments and estimate their financial impact in accordance with the requirements of the International Accounting Standard (IFRS 9) in case of uncertainty as a result of the Corona pandemic.
Fully-Integrated SPAD-Based Receiver with Nanosecond Dead Time for Optical Wireless Communication
Authors: Li Xianbo , Li Derun , Tang Chao , Liu Shaoxian 
Published: August 2022

<p>This paper presents the design and characterization of a fully-integrated receiver based on single-photon avalanche<br>
diodes (SPADs) with nanosecond dead time for high-speed high-sensitivity optical wireless communication (OWC). </p>
Modeling and Detection of Dynamic Position Sensor Offset Error in PMSM Drives
Authors: Kuruppu Sandun , Abeyratne Sunil , Hettiarachchi Sandun 
Published: August 2022

<p> Rotor position information obtained through a position sensor is crucial for proper field-oriented control (FOC) of permanent magnet synchronous machine based high dynamic energy conversion applications. In applications such as transportation and industrial, PMSM energy conversion systems are subjected to harsh environmental conditions such as vibration, shock, and thermal shock causing mechanical interfaces holding positions sensors to fail, introducing error to the position measurement. A dynamic position sensor offset error (DPSOE), being such a failure mode has the potential to degrade system torque output or more adversely, reverse machine torque output that may cause catastrophic outcomes. This paper evaluates different DPSOE scenarios, presents an approach to model the failure mode for analysis and proposes two novel and robust DPSOE detection methods for PMSM drive systems. The proposed detection methods are analytically proven and supported by simulation and experimental results under multiple operating conditions proving robustness. </p>
سلسلة كهوف الطار - دراسة في ضوء التحريات والتنقيبات الاثرية
Authors: الزيدي أباذر راهي 
Published: August 2022

تكثر الكهوف في المناطق الجبلية حيث تضافرت العوامل الطبيعية على تكوينها واستفاد الانسان من وجودها الطبيعي بالالتجاء اليها لحماية نفسه من العدو ومن قسوة البيئة الطبيعية وخصوصاً في العصور الحجرية القديمة.
تعد سلسلة كهوف الطار من المواقع الأثرية المهمة التابعة لمحافظة كربلاء المقدسة – قضاء عين التمر حيث تقع في القطعة رقم ( 3 ) مقاطعة ( 61 / الجزيرة ) وقد أعلن عن أثريته عام 4 / 3 / 1957 وهو غير مسجل ضمن دليل المواقع الآثرية في العراق لعام 1970 وقد نشر الموقع في جريدة الوقائع العراقية ضمن العدد ( 3987 ) في 1/1/2004 م واستنادا إلى البند أولاً من المادة الخامسة من قانون الآثار والتراث رقم 55 لسنة 2002 م ، لقد حددت البعثة الآثارية اليابانية برئاسة البروفيسور هيدو فوجي أن تاريخ كهوف الطار مرت بثلاثة أطوار ، الطور الأول عام ( 1300 ق.م ) والطور الثاني في عصر البارثيين أو العصر الفرثي ( 148 ق.م – 126 ب.م ) والطور الثالث في العصور الإسلامية ( 636 ب.م ).
سيتتبع البحث نشاط الإنسان القديم الذي ظهر لأول مرة في هذه البقعة من محافظة كربلاء المقدسة في (منطقة الطار)، ألا وهو إنسان العصر الحجري القديم، وفي ضوء ذلك قسم الى ثلاثة مباحث، تناول المبحث الأول نشأة الكهوف وبيئتها وأنواعها وتوزيعها في العراق والعالم، أما المبحث الثاني فقد تناول جغرافية الموقع الأثري سلسلة كهوف الطار وأهم المواقع الأثرية في منطقة الطار برمتها في حين اختص المبحث الثالث بالتحريات والتنقيبات العلمية التي أجريت في موقع سلسلة كهوف الطار وأهم الآثار التي خرجت بها تلك التنقيبات، وختم البحث باستنتاجات تم التوصل إليها خلال الدراسة.

The series of Al-Tar Caves are considered of important archaeological sites in the province of Karbala – district of Ain Al-Tamur, where located at the item number (3) County (61 / Jazera) has announced the archaeological site in the the newspaper of Al-Wathaq Al- Iraqia within the number (3987) in 1/1/2004 A.D.
Japanese mission Identified the historic area which has reached to this region, Japanese Professor Hedo Fuji Prime Mission archaeological in Iraq and head of the excavation mission in caves Tar has identified three phases interchanged by these caves, the first phase before three centuries B.C, the second period of the Parthians and the third Islamic era. The researchers and Archaeologist divides this region to the groups abbreviated by English letters (A, B, C, D, E, F (.
Caves Al-Tar many more than three hundred cave and the heights perhaps the most important discoveries of the Japanese mission in Tlul compound (A) in the Tar are small pieces of colored fabric is not possible to his discovery of the fabric similar in Mesopotamia because of the humidity that lead to the disintegration of the fabric, and the fact that the caves Al-Tar dry it helped the survival of the textile pieces without infect damage and disruption. It is useful to note that this technique textile industry shows that the creator artist professional and civilized. These pieces are similar to a large extent in the detected tissue (Palmyra) and features smooth texture like real silk.
الواقعة الفقهية التنوع والتوزيع في حركة الحكم الفقهي
Authors: عزيز حسن كاظم 
Published: August 2022

مع اختلاف الواقعة الفقهية كان لها ولا يزال القدر الجليل في الشريعة الاسلامية لأنها عماد تنظيم حركية المجتمع الديني سلوكا و دينا، مما يبعث على اساطين الفن الاحاطة بها دراسة وبحثا في مجالات علوم الشريعة و الحركة الاجتهادية خاصة، وبعد تعاقب الاجيال واختلاف الموضوعات في حركة الزمان والمكان في ظل المتغيرات اخذت الواقعة تتسع في مستحدثها الفقهي ، مما تطلب من الفقهاء وضع ضوابط تحرك الواقعة ضمن دائرة التشريع، وهذا قد ساهم بشكل فعـّال في عملية الاستدلال الفقهي في تشريع الاحكام ومتطلبات كل عصر، ويظهر ذلك في ابداع اساطين الفن في منهجه هذا العلم من خلال التقسيم و التبويب والتوزيع.

With the difference in jurisprudence has been and still is a great amount in Islamic law because it is the basis of the organization of the dynamics of the religious community behavior and religion, which raises the two aspects of art surrounded by study and research in the fields of science and the Shari'ah movement, especially after the succession of generations and different topics in the movement of time and place In light of the variables took the incident expands in the modern jurisprudence, which requires the scholars to establish the controls of the move within the circle of legislation, and this has contributed effectively to the process of reasoning in the jurisprudence of jurisprudence and the requirements of each era, and this shows in the creativity of the two aspects of art in the curriculum of this science through a For division, tab and distribution.
PENGARUH BEBAN OPERASIONAL DAN JUMLAH PASIEN TERHADAP LABA BERSIH PADA KLINIK JB MEDICAL CENTER CIKARANG
Authors: Triwibowo Edi , Lisdianti Lyan , Asiah Neng 
Published: August 2022

Setiap perusahan didirikan memiliki tujuan masing-masing, baik itu kepentingan bersama maupun individual. Salah satu tujuannya adalah pencapaian laba semaksimal mungkin. Sebelum pencapain laba bersih terdapat proses yang harus dilakukan oleh suatu perusahaan, diantaranya adalah kegiatan operasional suatu perusahaan. Dalam menjanlankan kegiatan operasional tersebut terdapat beberapa biaya biaya yang disebut juga beban operasional suatu perusahaan, dimana biaya- biaya atau beban tersebut harus dikurangkan dari pendapatan bruto selama kegiatan opersional, sehingga didapatkan laba bersih. Selain itu penjuaalan juga penting dalam prosese kegiatan operasional.
Dalam penelitian ini penulis mengambil penelitian di perusahaan yang bergerak dibidang jasa kesehatan, dimana selain beban operasional, jumlah pasien juga diperlukan dalam perolehan pendapatan yang berpengaruh pada laba perusahaan.
Penelitian ini bertujuan untuk mengetahui adakah pengaruh antara beban operasional dan jumlah pasien terhadap laba bersih perusahaan, secara bersamaan maupun sendiri - sendiri, serta seberapa kuat atau seberpa besar jika terdapat pengaruh. Dimana beben operasional dan jumlah pasien sebagai variabel independen (X1, X2) dan laba bersih sebagai variabel Dependent (Y).
Dalam penelitian ini menggunakan jenis penelitian Deskriptif-kuantitatif dan menggunakan sumber data skunder. Dengan teknik analisa data menggunakan bantuan program statistik, sofware SPSS 20 for windows. Analisis data yang dipakai berupa analisis regresi linear berganda untuk menjawab rumusan masalah. Jadi berdasarkan dari hasil perhitungan tersebut ada pengaruh negative antara Variabel X1 dengan Y dan terdapat pengaruh yang positif antaraVariabel X2 dengan variabel Y, sedangkan besar pengaruh antara variabel independen dan dependen sebesar 77%.
One-Village-One-Product: A Countryside Capitalization Approach to Alleviate Rural Poverty in Sri Lanka
Authors: Peiris T. U. I. , Aslam M. S. M. , Gnanapala W. K. A. C. , Wijekoon W. M. S. S. 
Published: August 2022

This study used a qualitative approach to investigate the potential of implementing the One-Village-One-Product countryside capitalization model in the Ridigama village. In-depth interviews, focus group discussions, and observations of the research team were mainly used in collecting data for the study. Research findings indicated that the village and the villagers are ominously dependent on the Ridi Viharaya, which is the main religious monument in the village. The village is abundant with natural and socio-cultural capital that can be used when implementing the model. Moreover, the willingness of the people in developing the concept and mainly the leadership of Mahanayake Thero of Ridi Viharaya were the main strengths possessed by this village in this regard. These findings led to the articulation of the One-Village-One-Product model considering Spiritual Tourism as the core of it. Finally, the findings of the study strongly recommended implementing the model with five key trust areas, namely; spiritual wellbeing; conservation of ecosystem/biodiversity; conservation of historically build environment; conservation of social-culture; and quality of tourism.
Role of anterior chamber maintainer in preventing pseudophakic retinal detachment in highly myopic eyes
Authors: Khater Ahmed A. , Eleiwa Taher K. , Elsaadani Ibrahim A. 
Published: August 2022

Purpose
To investigate the effect of anterior chamber maintainer (ACM) usage during phacoemulsification on the occurrence of pseudophakic retinal detachment (PRD) in high myopia.

Design
A retrospective nonrandomized comparative interventional study was conducted.

Participants
A total of 632 high myopic eyes of 501 patients who had eventless phacoemulsification with in-the-bag intraocular lens implantation in the period between March 2013 and December 2018.

Methods
Patients were divided into two groups according to the use of ACM during cataract surgery: (a) ACM group, and (b) no-ACM group. Patients were followed at 6, 12, 18, 24, 30, and 36 months after surgery for detection of PRD. The time-related cumulative incidence of RD in each group was evaluated by means of Kaplan–Meier survival curves.

Results
In the ACM group, the 3-year cumulative incidence of RD was 2.4% compared with 5.9% in the other group (P=0.039). Regarding age, the 3-year cumulative incidence of RD increased significantly in the younger age group when the ACM was not used (P=0.023), whereas it was not when the ACM was used. Using the ACM increased the 3-year cumulative survival ratio from 86.2 to 92% in patients with a posterior staphyloma (P=0.03).

Conclusion
ACM is a potential prophylactic intraoperative tool against PRD in highly myopic eyes.
Incremental Value of Left Atrial Function Analysis in the Assessment of Left Ventricular Filling Pressures in Patients with ST-Elevation Myocardial Infarction
Authors: Longobardo Luca , Zito Concetta , D’Amico Gessica , Ioppolo Annamaria , Terrizzi Anna , Oteri Alessandra , Cusmà-Piccione Maurizio 
Published: August 2022

Background:
Left atrial (LA) reservoir strain provides interesting information about left ventricular (LV) filling pressure. However, the advantages of atrial reservoir strain in comparison with conventional parameters in patients with myocardial infarction are not clear yet.

Methods:
Fifty patients with ST-elevation myocardial infarction (STEMI) prospectively underwent echocardiographic assessment of LV systolic and diastolic function by conventional parameters and two-dimensional speckle tracking longitudinal strain of left atrium. LV filling pressure was estimated by brain natriuretic peptide (BNP) levels.

Results:
Systolic and conventional diastolic parameters did not show significant differences between patients with increased and normal BNP values, whereas LA reservoir strain was reduced (33.1 ± 8% vs. 46.5 ± 9.8%; P = 0.001) in patients with higher BNP levels. LA reservoir strain had higher area under curve value (0.880) than the other parameters in identifying patients with elevated BNP and a cut-off value of 40.5% reached sensitivity and specificity values of 93% and 86% and positive and negative predictive values of 92% and 85%. LA reservoir strain reclassified 23 patients with increased BNP values, which were previously estimated to have normal (16 patients) and undeterminable LA pressure (seven patients) by using the recommended algorithm for diastolic function.

Conclusions:
LA reservoir strain is a useful tool for the evaluation of diastolic function and seems to be more sensitive than conventional parameters in the detection of subtle increase of LV filling pressure in patients with STEMI. It allows physicians to reclassify patients with undeterminable diastolic function according to conventional algorithm.
Regular scientific paper reading as an approach to improve the outcome of bioinformatics teaching to graduate students of medical majors
Authors: Zhang Xiangning , Huan Jing , Wu Longji , Huang Zhi-Gang , He Zhiwei , Yu Hongbing 
Published: August 2022

Since the elucidation of the double helix structure of DNA molecule and its role of coding for genetic information, rapid progress of biomedical science including the sequencing of macromolecules in the living system has been witnessed. The technique has allowed the study field to evolve from single genes to genome in species. With demand of deposit and analysis of data obtained, a new science bioinformatics has been formed by integration of computer science and biology. Bioinformatics has found wide application in research of different disciplinary in medical science. To facilitate the grasp of its basic theory and practical application by the postgraduate students at the medical school, regular reading of relevant publications has been proposed as an approach to improve the quality of teaching, and its outcome has been evaluated by comparing the scores earned from the identical test papers. The students acquired the designed intervention had higher score in average statistically with p<0.01.