bluuebunny/crossref_metadata_2025_split huggingface dataset:
Activation of Neural Modeling-Related Genes in the Heart of Mice after Gamma Irradiation
Authors: Liu Zhiyong , Liu Jing , Hu Dan , Du Juanjuan , Liu Donglu , Wang Ximin , Zhang Jiandong , Hou Yinglong 
Published: December 2021

Objective. Radiation-induced heart disease (RIHD) is a common sequela of thoracic irradiation. At the same time, nerve remodeling is involved in the progression of heart disease. However, the activation of the nerve remodeling related genes in radiation-induced heart disease is still lacking. Methods. In this study, C57BL/J mice was anesthetized by intraperitoneal injection with pentobarbital sodium (2%, 40 mg/kg), and radiation was delivered using a cobalt-60 (60Co) teletherapy unit (Cirus). When the mice were anesthetized, none of them showed the signs of peritonitis, pain, or discomfort. The mice hearts were exposed to a γ-radiation field of

5

mm
×
5

mm

. The total dose of γ-radiation was 3 Gy/day for each animal for 5 consecutive days. The mice were executed by severed neck, and its limbs were weak. Quantitative Polymerase Chain Reaction (qPCR) and immunohistochemistry were used to explore the possible mechanism of arrhythmia in patients with RIHD. Results. Our results demonstrated that Growth-Associated Protein 43 (GAP43) was increased significantly after radioactive heart injury compared with the control group. Moreover, the protein expression of Tyrosine hydroxylase (TH) and Choline acetyl-transferase (CHAT) was significantly decreased compared with the control group and gradually increased with time rend. The nerve growth factor (NGF) was remarkably increased after radiation-induced heart injury compared with the control group. Immunohistochemistry results indicated that the nerve growth factors GAP43 and NGF were significantly increased after radiation-induced heart injury. Conclusions. Chest radiotherapy could activate the neural modeling related genes in RIHD. This may provide a new treatment plan for the future treatment of heart problems caused by chest radiotherapy.
Integración de la educación interprofesional: autodiagnóstico para programas de salud
Authors: Olivares Olivares Silvia , López Cruz Claudia 
Published: December 2021

Introducción: la educación interprofesional se produce cuando dos o más profesionales se conocen y se relacionan entre sí para permitir una colaboración eficaz con la intención de mejorar los resultados de salud. Diferentes marcos de referencia de identidad profesional y competencias han establecido la importancia de este tipo de formación. Sin embargo, cada programa puede contar con diferentes niveles de implementación para integrarlo en el mismo. Método: el objetivo del presente trabajo fue desarrollar un instrumento de autodiagnóstico sobre Integración de la Educación Interprofesional en los programas de salud, considerando su formalización y despliegue. Se utilizó una validación de expertos para el diseño del instrumento y una prueba piloto con directivos de cinco programas de salud. Resultados: el instrumento consta de 12 ítems para valorar si los alumnos cuentan con condiciones formativas interprofesionales: 1) Identifican, 2) Colaboran, 3) Toman decisiones y 4) Construyen soluciones. Para ello la institución educativa puede A. Definir, B. Comunicar, C. Formar, D. Evaluar o E. Mejorar las intervenciones formativas para garantizar una implementación adecuada de dichos propósitos. El modelo resultante es una guía taxonómica que permite identificar la formalización de la implementación cada una de las competencias en un programa de salud. Conclusiones: el instrumento propuesto cuenta con contenidos comprensibles y adecuados para cumplir con sus propósitos de autodiagnóstico en la formalización en la implementación de competencias interprofesionales. Sin embargo, más que un carácter estrictamente incremental, confiere una visión dinámica en la cual pueden implementarse escalas superiores sin haber cerrado un ciclo de mejora completo en las competencias previas.
Effective Study: Development and Application of a Question‐Driven, Time‐Effective Cardiac Magnetic Resonance Scanning Protocol
Authors: Torlasco Camilla , Castelletti Silvia , Soranna Davide , Volpato Valentina , Figliozzi Stefano , Menacho Katia , Cernigliaro Franco , Zambon Antonella , Kellman Peter , Moon James C. , Badano Luigi P. , Parati Gianfranco 
Published: December 2021

Background
Long scanning times impede cardiac magnetic resonance (CMR) clinical uptake. A “one‐size‐fits‐all” shortened, focused protocol (eg, only function and late‐gadolinium enhancement) reduces scanning time and costs, but provides less information. We developed 2 question‐driven CMR and stress‐CMR protocols, including tailored advanced tissue characterization, and tested their effectiveness in reducing scanning time while retaining the diagnostic performances of standard protocols.

Methods and Results

Eighty three consecutive patients with cardiomyopathy or ischemic heart disease underwent the tailored CMR. Each scan consisted of standard cines, late‐gadolinium enhancement imaging, native T1‐mapping, and extracellular volume. Fat/edema modules, right ventricle cine, and in‐line quantitative perfusion mapping were performed as clinically required. Workflow was optimized to avoid gaps. Time target was <30 minutes for a CMR and <35 minutes for a stress‐CMR. CMR was considered impactful when its results drove changes in diagnosis or management. Advanced tissue characterization was considered impactful when it changed the confidence level in the diagnosis. The quality of the images was assessed. A control group of 137 patients was identified among scans performed before February 2020. Compared with standard protocols, the average scan duration dropped by >30% (CMR: from 42±8 to 28±6 minutes; stress‐CMR: from 50±10 to 34±6 minutes, both
P
<0.0001). Independent on the protocol, CMR was impactful in ≈60% cases, and advanced tissue characterization was impactful in >45% of cases. Quality grading was similar between the 2 protocols. Tailored protocols did not require additional staff.

Conclusions
Tailored CMR and stress‐CMR protocols including advanced tissue characterization are accurate and time‐effective for cardiomyopathies and ischemic heart disease.
Sodium‐Glucose Co‐Transporter 2 (SGLT2) Inhibitor Dapagliflozin Stabilizes Diabetes‐Induced Atherosclerotic Plaque Instability
Authors: Chen Yung‐Chih , Jandeleit‐Dahm Karin , Peter Karlheinz 
Published: December 2021

Background
Diabetes is known to accelerate atherosclerosis and increase plaque instability. However, there has been a lack of suitable animal models to study the effect of diabetes on plaque instability. We hypothesized that the tandem stenosis mouse model, which reflects plaque instability/rupture as seen in patients, can be applied to study the effects of diabetes and respective therapeutics on plaque instability/rupture.

Methods and Results

ApoE
−/−
mice at 7 weeks of age were rendered diabetic with streptozotocin and 5 weeks later were surgically subjected to tandem stenosis in the right carotid artery and fed with a high‐fat diet for 7 weeks. As a promising new antidiabetic drug class, a sodium glucose co‐transporter 2 inhibitor was tested in this new model. Diabetic mice showed an increase in the size of unstable atherosclerotic plaques and in the plaque instability markers MCP‐1, CD68, and necrotic core size. Mice treated with dapagliflozin demonstrated attenuated glucose and triglyceride levels. Importantly, these mice demonstrated plaque stabilization with enhanced collagen accumulation, increased fibrosis, increased cap‐to‐lesion height ratios, and significant upregulation of the vasculoprotective NADPH oxidase 4 expression.

Conclusions
The tandem stenosis mouse model in combination with the application of streptozotocin represents a highly suitable and unique mouse model for studying plaque destabilization under diabetic conditions. Furthermore, for the first time, we provide evidence of plaque‐stabilizing effects of sodium‐glucose co‐transporter 2 inhibitor. Our data also suggest that this newly developed mouse model is an attractive preclinical tool for testing antidiabetic drugs for the highly sought‐after potential to stabilize atherosclerotic plaques.
Leaving Home, Claiming the Street: Exploring Women’s Challenges in Turkey’s ’68 Movement
Authors: Tuncer Selda , Taştan İnan Özdemir 
Published: December 2021

Abstract
Despite worldwide interest in the history of the sixties—particularly in 1968—gender as a category of analysis has received little attention in the majority of academic research about them. Most national historiographies of ’68 have disregarded women’s political actions and their struggles with the gendered political culture. Like its counterparts, Turkey’s ’68 experience was also strongly gendered male. Given the underrepresentation of female historical agency and political subjectivity in the scholarship on 1968, this article aims to explore women’s accounts of Turkey’s ’68 experience with a particular focus on their struggles in leaving home and getting involved in political life.
“Turkey Will Be a Second France, Unless Our Demands Are Satisfied”: The Turkish Student Movement in the Long 1960s
Authors: Christofis Nikos 
Published: December 2021

Abstract
The transnational phenomenon that was “1968” was felt keenly around the globe with direct and virtually immediate impact. Turkey stands as a clear example, wherein the development and dynamism of the “Western” student movement had an immediate impact and shaped developments unfolding in Turkey at the time. As elsewhere in the world, “1968” did not hit Turkey out of thin air. The “1968 generation,” and the student movement in general, was mainly Kemalist, one of the significant characteristics that differentiated it from others. It first emerged as a student movement focused on reform within the university system, but toward the end of the 1960s, it evolved into a revolutionary movement, eventually deploying revolutionary violence from 1971–72.
Anti-Imperialism and Kemalism in Turkey’s Long Sixties: Mahir Çayan’s Theory of Revolution in Context
Authors: Ülker Erol 
Published: December 2021

Abstract
This article aims to reassess the evolution of Mahir Çayan’s theory of uninterrupted revolution in the context of the radical ideological currents of the long sixties in Turkey. It concentrates on Çayan’s relations with the National Democratic Revolution (Milli Demokratik Devrim, mdd) movement that enjoyed a considerable degree of political and ideological authority over the youth movements starting in the second half of the 1960s. The article discusses how Çayan interpreted and attempted to revise the theory of national democratic revolution by reference to the changing characteristics of imperialism and colonial domination. Consideration is given to Çayan’s critical approach towards the role of Kemalists in the anti-imperialist bloc to be formed.
Crossmodal Correspondence Between Auditory Timbre and Visual Shape
Authors: Gurman Daniel , McCormick Colin R. , Klein Raymond M. 
Published: December 2021

Abstract
Crossmodal correspondences are defined as associations between crossmodal stimuli based on seemingly irrelevant stimulus features (i.e., bright shapes being associated with high-pitched sounds). There is a large body of research describing auditory crossmodal correspondences involving pitch and volume, but not so much involving auditory timbre, the character or quality of a sound. Adeli and colleagues (2014, Front. Hum. Neurosci. 8, 352) found evidence of correspondences between timbre and visual shape. The present study aimed to replicate Adeli et al.’s findings, as well as identify novel timbre–shape correspondences. Participants were tested using two computerized tasks: an association task, which involved matching shapes to presented sounds based on best perceived fit, and a semantic task, which involved rating shapes and sounds on a number of scales. The analysis of association matches reveals nonrandom selection, with certain stimulus pairs being selected at a much higher frequency. The harsh/jagged and smooth/soft correspondences observed by Adeli et al. were found to be associated with a high level of consistency. Additionally, high matching frequency of sounds with unstudied timbre characteristics suggests the existence of novel correspondences. Finally, the ability of the semantic task to supplement existing crossmodal correspondence assessments was demonstrated. Convergent analysis of the semantic and association data demonstrates that the two datasets are significantly correlated (−0.36) meaning stimulus pairs associated with a high level of consensus were more likely to hold similar perceived meaning. The results of this study are discussed in both theoretical and applied contexts.
The Musical Diplomacy of Metternich
Authors: Mahiet Damien 
Published: December 2021

Abstract
That festivities are woven into the historical image of the Austrian diplomat, foreign minister, and state chancellor Clemens von Metternich (1773–1859) is in part the byproduct of his investment in music. As an amateur performer, passionate connoisseur, attentive patron, and frequent host, Metternich cultivated an international soundworld that presented opportunities for cooperative performances. Ensemble music and collective listening provided experiences of international concert that gained significance in the context of multilateral congresses and meetings. Musical exchanges, sustained through the activity of women and professional musicians, contributed to fostering diplomatic relations and international presence. In the context of the Restoration’s competing soundworlds, Metternich deployed a patronage of Rossini’s work and Italian opera music, with increasing intensity but mixed effect. This history speaks to the function of music in the presentation of self in international encounters and the resources to be found in the plurality of roles diplomats perform.
Współczesna sytuacja na Grodzieńszczyźnie w ujęciu socjolingwistycznym
Authors: Ostrówka Małgorzata 
Published: December 2021

The Contemporary Situation in the Grodno Region in a Sociolinguistic PerspectiveReview Katarzyna Konczewska, Polacy i język polski na Grodzieńszczyźnie [Poles and the Polish Language in the Grodno Region], Kraków: Instytut Języka Polskiego Polskiej Akademii Nauk, 2021, 192 pp.This article is a review of Katarzyna Konczewska’s study entitled Polacy i język polski na Grodzieńszczyźnie [Poles and the Polish Language in the Grodno Region]. The study discusses the history and geographical extent of the area under consideration as well as the sociolinguistic situation and the functional distribution of the Polish language in the region. The author also presents a list of features of North Borderland Polish in the collected texts, published sources – the novels of Eliza Orzeszkowa (Nad Niemnem [On the Niemen], Cham [The Peasant], Dziurdziowie [The Dziurdzia Family]), the prose of Aleksander Jurewicz, and books published in Polish in Belarus – and analyses the language of Polish tombstone inscriptions. It is worth noting that the publication includes a number of tables, full colour charts, maps and photos. The study is an important contribution to the literature on the functioning of the Polish language in Belarus. Współczesna sytuacja na Grodzieńszczyźnie w ujęciu socjolingwistycznymRecenzjaKatarzyna Konczewska, Polacy i język polski na Grodzieńszczyźnie, Kraków: Instytut Języka Polskiego Polskiej Akademii Nauk, 2021, 192 ss.Artykuł jest recenzją książki Katarzyny Konczewskiej pt. Polacy i język polski na Grodzieńszczyźnie. Autorka omawia w niej historię, zasięg geograficzny badanego obszaru, sytuację socjolingwistyczną oraz dystrybucję funkcjonalną języka polskiego. Przedstawia także wykaz cech polszczyzny północnokresowej w zgromadzonych tekstach, źródłach publikowanych – w powieściach Elizy Orzeszkowej (Nad Niemnem, Cham, Dziurdziowie), w prozie Aleksandra Jurewicza, białoruskich polskojęzycznych publikacjach książkowych. Analizuje też język polskich inskrypcji nagrobnych. Na uwagę zasługuje szata graficzna publikacji – tabele, kolorowe wykresy, mapy i zdjęcia. Książka jest ważnym uzupełnieniem literatury na temat funkcjonowania języka polskiego na Białorusi.
Dwujęzyczne hybrydy składniowe w tekstach naukowych
Authors: Duszkin Maksim 
Published: December 2021

Bilingual Syntactic Hybrids in Scientific TextsThis article is devoted to the phenomenon of such quotation of foreign language lexemes whereby their form depends on the syntactic requirements of the language in which the main text is written, e.g. “dojść do соглашения”. Connections of this type can sometimes also be found in scientific publications, e.g. in articles in Polish describing the Russian language (lexical or grammatical issues, etc.) or Russian cultural and political realities. The study analyses this phenomenon on the basis of selected examples. In sentences quoting foreign language material in this way, the boundary between two languages (e.g. Ukrainian and Polish, Belarusian and Russian, etc.) and their respective syntactic systems is blurred. Dwujęzyczne hybrydy składniowe w tekstach naukowychW artykule omówione zostało zjawisko takiego przytaczania leksemów obcojęzycznych w tekście, w którym ich forma staje się zależna od wymagań składniowych języka, w jakim napisany jest tekst podstawowy, por. np. „dojść do соглашения”. Połączenia tego typu można czasami spotkać także w publikacjach naukowych, np. w artykułach w języku polskim, opisujących język rosyjski (leksykalnie, gramatycznie itd.) lub np. rosyjskie realia kulturowe i polityczne. W artykule zjawisko to zostało przeanalizowane na podstawie wybranych przykładów. W zdaniach operujących omawianym typem przytaczania materiału obcojęzycznego dochodzi do zacierania granicy pomiędzy dwoma językami (np. ukraińskim i polskim, białoruskim i rosyjskim) oraz ich systemami składniowymi.
Dawne polskie intensyfikatory wywodzące się od staroczeskiego "přieliš"
Authors: Mitrenga Barbara 
Published: December 2021

Historical Polish Intensifiers Derived from the Old Czech přielišThis article is devoted to a historical-linguistic analysis of the equivalents of the Old Czech přieliš in historical Polish: the words bezlisz, brzezlisz, przelisz, przezlisz and przylisz. The study refers to key findings of researchers about these words, their origins and meaning. On the basis of analysis of linguistic material the author formulates conclusions about word-formation of the equivalents of přieliš in Polish, their frequency in monuments of Polish literature from the Old Polish period to the end of the sixteenth century, their meaning and status in Polish, as well as presumable causes of their disappearance from the language. The paper presents examples that confirm their functioning in monuments of the Polish language, such as Biblia królowej Zofii [Queen Sophia’s Bible] from the mid-fifteenth century and Biblia Jana Leopolity [John Leopolita’s Bible] from 1561, as well as in dictionaries of Polish. The study also considers information about Old Czech and compares parallel verses of Polish and Czech Bible translations. Dawne polskie intensyfikatory wywodzące się od staroczeskiego přielišArtykuł poświęcony jest historycznojęzykowej analizie odpowiedników staroczeskiego přieliš, czyli wyrazów bezlisz, brzezlisz, przelisz, przezlisz i przylisz w dawnej polszczyźnie. Autorka przytacza najważniejsze opinie badaczy o wymienionych wyrazach, ich pochodzeniu i znaczeniu. Na podstawie analizy materiału językowego formułuje wnioski dotyczące budowy słowotwórczej staroczeskich odpowiedników přieliš w języku polskim, ich frekwencji w zabytkach literatury polskiej od staropolszczyzny do końca XVI w., znaczenia i statusu tych wyrazów w polszczyźnie, a także przypuszczalnych przyczyn ich zaniku. W artykule przedstawiono przykłady potwierdzające funkcjonowanie wspomnianych wyrazów zarówno w zabytkach języka polskiego m.in. w Biblii królowej Zofii z połowy XV w. i Biblii Jana Leopolity z 1561 r., jak i w słownikach języka polskiego. Ponadto autorka przywołuje informacje o staroczeskim i porównuje równoległe wersety przekładów Biblii na język polski i czeski.
Wspomnienie Prof. dr hab. Kwiryna Handke (1932–2021)
Authors: Masłowska Ewa 
Published: December 2021

In Memoriam: Professor Dr hab. Kwiryna Handke (1932–2021)This article is an obituary of Professor Kwiryna Handke (1932–2021), a renowned linguist, Polish philologist, Slavist and Warsaw studies scholar, associated with the Institute of Slavic Studies, Polish Academy of Sciences for several decades. She served as Deputy Director (1990–1996) and Director of the Institute (1996–1999), Head of the Institute’s Academic Council (2007–2010), and Editor-in-Chief of the journal Studia z Filologii Polskiej i Słowiańskiej (2001–2013). Wspomnienie. Prof. dr hab. Kwiryna Handke (1932–2021)Artykuł jest wspomnieniem prof. dr hab. Kwiryny Handke (1932–2021), nestorki Instytutu Slawistyki Polskiej Akademii Nauk, od 1990–1996 wicedyrektora, a w latach 1996–1999 dyrektora IS PAN, Przewodniczącej Rady Naukowej IS PAN (2007–2010), byłej redaktor naczelnej „Studiów z Filologii Polskiej i Słowiańskiej” (2001–2013), językoznawcy, polonistki, slawistki i varsavianistki.
The Cult of the Martyr: The Symbol of Stanisław Wacławski and Rituals of Violence in the Warsaw Student Milieu of the 1930s
Authors: Mrzygłód Izabela 
Published: December 2021

The Cult of the Martyr: The Symbol of Stanisław Wacławski and Rituals of Violence in the Warsaw Student Milieu of the 1930sViolence was a key element of the interwar radical habitus and was particularly affirmed in far-right movements, which found fertile ground for their ideas among students. However, the influence of the systems of ideas advocated by ideologues on student masses seems limited and indirect. Student support for antisemitism and extremism cannot be explained only by cultural conditions, ideology or political engineering. What is needed here are intermediate stages, linking radical ideology with the actions of social actors. I argue that the intermediary function was performed by the symbol of Stanisław Wacławski, a student and member of the Camp of Great Poland (Obóz Wielkiej Polski) who was killed during the antisemitic riots in Vilnius in 1931. The figure of Wacławski was a key element of antisemitic discourse in far-right press and was used by academic societies to construct the annual ritual of violence in the 1930s. I employ the micro-sociological approach and draw on Randall Collins’ theory of “interaction ritual chains” to show that the factors behind the mobilization of ordinary students for collective violence and a chauvinistic agenda included also emotions and personal relations, and not only political identification and advertising. Kult męczennika. Symbol Stanisława Wacławskiego i rytuały przemocy w warszawskim środowisku studenckim lat trzydziestych XX wiekuW habitusie międzywojennych radykałów przemoc grała kluczową rolę i była szczególnie afirmowana w ruchach skrajnie prawicowych, które znajdowały podatny grunt dla swoich idei w środowiskach studenckich. Jednak wpływ systemów idei głoszonych przez ideologów na masy studenckie wydaje się ograniczony i pośredni. Poparcia studentów dla antysemityzmu i ekstremizmu nie można tłumaczyć jedynie uwarunkowaniami kulturowymi, ideologią czy inżynierią polityczną. Potrzebne są tu etapy pośrednie, łączące radykalną ideologię z działaniami aktorów społecznych. W niniejszym tekście dowodzę, że funkcję taką pełnił w środowisku akademickim symbol w postaci Stanisława Wacławskiego, studenta i członka Obozu Wielkiej Polski, który zginął podczas antysemickich zamieszek w Wilnie w 1931 roku. Jego postać stanowiła kluczowy element antysemickiego dyskursu prasy skrajnej prawicy i była wykorzystywana przez stowarzyszenia akademickie do konstruowania corocznego rytuału przemocy w latach 30. Aby pokazać, że czynnikami, które wyjaśniają, w jaki sposób zwykli studenci byli mobilizowani do zbiorowej przemocy i pozyskiwani dla szowinistycznego programu, były również emocje i osobiste relacje, a nie tylko identyfikacja polityczna i agitacja, stosuję podejście mikrosocjologiczne i czerpię z teorii „łańcuchów rytuałów interakcji” Randalla Collinsa.