bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding How Malaysian Women Appraise their Breast Cancer Symptoms: A Narrative Approach
Authors: Wan Mamat Wan Hasliza , Lund Susi , Jarrett Nikki , Mohd Taib Nur Aishah , Duke Sue 
Published: April 2022

INTRODUCTION: Awareness of breast cancer symptoms has made a positive impact on recognition and screening, however there is little research describing how women interpret their bodily changes. This study was conducted to explore how Malaysian women with breast cancer appraise their symptoms and how their interpretation of the symptoms had been shaped by the social norms, knowledge and previous experiences. Materials and Methods: 14 women with breast cancer were recruited using purposeful sampling. The participants took part in in-depth, one-time, face-to-face, and audio-recorded interviews. All the interviews were subsequently transcribed verbatim and analysed using structure and content of a narrative approach. Results: Women interpreted their symptoms based on the physical presentation of the symptoms, previous experiences, and societal norms and beliefs. Some women immediately understood the potential meaning of their breast changes and sought medical opinion, while others waited from one week up to until one year to observe symptoms or normalised them in terms of previous and current experiences. The use of narrative enabled these women to recapitulate particular experiences that had special meaning in order to make sense of their action. Conclusions: The way women interpreted their symptoms reflected their understanding on the significant meaning of the symptoms. Acknowledging this symptom appraisal information may assist healthcare professionals in providing appropriate information that can challenge misconceptions, myths, and negative beliefs about breast cancer to improve breast cancer awareness and early detection among the community.
Pendapatan Petani dan Efisiensi Pemasaran Kopi Robusta (Coffea sp) di Kecamatan Rumpin, Bogor
Authors: Maulana Asep Stevi , Suwarnata Anak Agung Eka , Humaira Linar 
Published: April 2022

ABSTRAK Kabupaten/Kota Bogor yang masuk dalam wilayah Jawa Barat, memiliki luas lahan kopi rakyat terluas kedua di Jawa Barat yaitu 6.418,00 hektare dan Kecamatan Rumpin sebagai salah satu bagian dari wilayah tersebut yang menghasilkan kopi. Peningkatan produksi kopi akan terwujud bila diikuti dengan pembenahan tingkat pendapatan petani. Hal tersebut harus dikondisikan dengan merangsang petani untuk menambah produktivitas yaitu menambah harga yang diterima oleh petani. Usaha tersebut dapat dilakukan dengan memperbaiki sistem pemasaran pada bagian efisiensi pemasaran. Petani kopi di Kecamatan Rumpin belum sepenuhnya mengetahui pendapatan serta efisiensi pemasaran kopi, sehingga dirasakan penting untuk melakukan penelitian tentang pendapatan petani kopi dan efisiensi pemasaran kopi robusta mulai dari petani sebagai produsen hingga konsumen atau organisasi akhir dalam pemasaran kopi robusta. Hasil penelitian diperoleh pendapatan petani kopi berada di atas Upah Minimum Provinsi Jawa Barat yaitu Rp1.810.351,36. Terdapat dua saluran pemasaran di daerah penelitian yakni saluran dari petani ke pedagang pengepul besar lalu ke pedagang eksportir. Saluran pertama berlangsung untuk jenis biji kering (green bean) curah/asalan. Saluran pemasaran kedua yaitu dari petani ke kelompok tani, kemudian dijual ke coffee shop. Saluran pemasaran kedua berlaku untuk jenis kopi biji kering sortir. Kedua saluran pemasaran tersebut sudah efisien karena memiliki nilai efisiensi pemasaran <50%. ABSTRACT Bogor Regency/City, which is included in the West Java region, has the second largest community coffee area in West Java which is 6,418.00 hectares and Rumpin District as one part of the area that produces coffee. The increase in coffee production will be realized if it is followed by improving the level of farmers' income. This must be conditioned by stimulating farmers to increase productivity, namely increasing the price received by farmers. This effort can be done by improving the marketing system in the marketing efficiency section. Coffee farmers in Rumpin District do not yet fully understand the income and efficiency of coffee marketing, so it is important to conduct research on the income of coffee farmers and the marketing efficiency of robusta coffee, starting from farmers as producers to consumers or the final organization in marketing robusta coffee. The results showed that the income of coffee farmers was above the West Java Province Minimum Wage, which was Rp. 1,810,351.36. There are two marketing channels in the research area, namely the channel from farmers to wholesalers and then to exporters. The first channel is for the type of dry beans (green beans) in bulk. The second marketing channel is from farmers to farmer groups, then sold to coffee shops. The second marketing channel applies to the type of dry-sorted coffee beans. Both marketing channels are efficient because they have a marketing efficiency value of <50%.
EVALUATION OF INTRACRANIAL SPACE OCCUPYING LESIONS BY CT PERFUSION STUDY
Authors: Jain Ramesh , Bhojwani Rajendra 
Published: April 2022

Introduction: CT perfusion plays an invaluable role here as it detects microscopic differences in the internal vascularity of lesions and aids in their characterisation and significantly raises the diagnostic accuracy. In this Retrospective study, we performed CT Perfusion in various intracranial focal lesions and studied their perfusion characters and tried to evaluate & differentiate between them.
Methods: This Retrospective Analytical study involved data of 100 of the randomly selected patients ( candidates / study subjects .CTP was performed with dual?slice dynamic multi?detector CT scanner in 100 patients prior to surgery or stereotactic biopsy with age ranging from 15 to 70 years. Patients below 15 years, pregnant women, and very old patients with compromised renal functions were not included in this study. It was noted that Informed consent was taken from all patients .
Results: Perfusion parameters like rCBF and rCBV were calculated with ROI including the whole of the lesion and 1?2 cm in the periphery of the lesion. The rCBF and rCBV of neoplastic lesions with statistically significant difference in rCBF and rCBV of low?grade gliomas from high?grade gliomas, lymphomas, and metastases.There was statistically significant difference in rCBF (P < 0.002) and rCBV (P < 0.001) of TWT, TOT, and abscesses.
Keyword: ICSOL , CT Perfusion , Cerebral blood flow , Cerebral blood volume.
A Clinical Study of Complications of Diphtheria
Authors: Arora Raj Kumar , Arora Prem Kumar 
Published: March 2022

Background: Diphtheria is a localized infection of mucous membrane or skin. To study complication of diphtheria.
Methods: In this study all cases of diphtheria and all age groups which attended department of ENT.
Results: It was observed that most common post diphtheria complication was myocarditis (23.00%). In neurological complication most common was palatal palsy followed by pharyngeal palsy and motor weakness.
Conclusion: In order to prevent complication of the disease active immunization is customary and in order to detect the disease at early stage and for prompt treatment masses should be educated regarding the dreadful nature of the disease.
Keywords: Diphtheria, Outcomes, Complication
The Characteristics and Function of Internalin G in Listeria monocytogenes
Authors: Gou Huitian , Liu Yuanyuan , Shi Wenjing , Nan Jinyu , Wang Chuan , Sun Yanan , Cao Qihang , Wei Huilin , Song Chen , Tian Changqing , Wei Yanquan , Xue Huiwen 
Published: April 2022

Abstract
In order to clarified characteristics and function of internalin G (inlG) in Listeria monocytogenes ATCC®19111 (1/2a) (LM), the immune protection of the inlG was evaluated in mice, the homologous recombination was used to construct inlG deletion strains, and their biological characteristics were studied by the transcriptomics analysis. As a result, the immunization of mice with the purified protein achieved a protective effect against bacterial infection. The deletion strain LM-AinlG was successfully constructed with genetic stability. The mouse infection test showed that the virulence of LM was decreased after the deletion of the inlG gene. The deletion strain showed enhanced adhesion to and invasion of Caco-2 cells. Compared to the wild strain, 18 genes were up-regulated, and 24 genes were down-regulated in the LM-AinlG. This study has laid a foundation for further research on the function of inlG and the pathogenesis of LM.
In this study, immunization of mice with the purified inlG protein achieved a protective effect against Listeria monocytogenes infection. The virulence of LM-ΔinlG was decreased by mouse infection. However, the adhesion and invasion ability to Caco-2 cell were enhanced. Compared to the wild strain, 18 genes were up-regulated, and 24 genes were down-regulated in the LM-ΔinlG. This study has laid a foundation for further study of the function of the inlG and the listeriosis.
Naive bayes algorithm performance for smartphone sentiment analysis in social media
Authors: Sarifah Monalisa Fatmawati 
Published: April 2022

Indonesia with a population of 250 million is a large market, Millennials tend to be more adaptive to the development of communication technology [1]. There are lot of opportunities that are used by various groups, one of which is the need to use smartphones that can make it easier for people to exchange information [2]. Â The shift in sales of smartphone brands in Indonesia is influenced byÂ massive advertising carried out by smartphone vendors (smartphone capitalists) to consumers [3]. The enthusiasm of the community in welcoming this platform is so great, lot of comment about smartphone brand stated by public is an interesting thing to be processed to be information. Utilization of that information requires analytical techniques so that the produced information can help many parties. The method used in this study is NaÃ¯ve Bayes classification method which is a learning technique for data mining algorithms that uses probability and statistical methods [4]. This method is used to classify comments given by the community to smartphone brands. The comments given in this application will later be classified into positive, negative, and neutral comments. The purpose of this study was to find out how much positive, negative and neutral comments the community gave to smartphone brands, so that later it would facilitate the smartphone brand in providing policies or development in the future.
The Profile of Cervical Cancer Patients at Soedarso Hospital
Authors: Pratiwi Sari Eka , Trianto Heru Fajar , Fatinah Nabilah Nurul , Ilmiawan Muhammad In’am , Fitrianingrum Iit , Lestari Desriani 
Published: April 2022

Background: The prevalence and mortality rates of cervical cancer differ by region with the highest rates found in Latin America, Southeast Asia, and Africa. In Indonesia, cervical cancer is the second-largest contributor to the latest cases in 2020. In West Kalimantan, over 20,000 women were diagnosed with cervical cancer in 2014. This study aims to describe the characteristics of cervical cancer patients in West Kalimantan. Methods: A descriptive observational study was conducted on patients from 2017 to 2019 according to the Soedarso Hospital database. All medical records were reviewed and analyzed to obtain the variable data; they were age, ethnics, origin, stage of cervical cancer, histopathology types, and hemoglobin (Hb) level. Results: Cervical cancer patients for the 2017–2019 period totaled 147 people with 30 deaths. In this study, 97 patients from 2017 to 2019 met the inclusion criteria. Cervical cancer was found from the age of 27 years with a peak at the age of 41–60 years. Most patients came from Pontianak and Kubu Raya cities (45.4% and 14.4%, respectively) with the most ethnic groups being Malays (41.2%). A total of 43.3% of patients had a parity amount of more than five times. Most patients came at stage IIIb (45.4%). The patients present with moderate to severe anemia with the lowest Hb level of around 2.3 g/dL. Based on histopathology, the type of squamous cell carcinoma ranks the highest (70.1%). Conclusions: Cervical cancer incidence reaches the peak at adults to elderly. The amount of parity seems to contribute to the incidence of cervical cancer in West Kalimantan. Most patients came at an advanced stage and the type of squamous cell carcinoma with moderate to severe anemia
Caracterização e Acesso aos Cuidados em Saúde de um Serviço Referência do Processo Transexualizador no SUS
Authors: Santos Eliane Jucielly Vasconcelos , Melo Camila Pimentel Lopes de 
Published: April 2022

Introdução: A transexualidade é um conjunto de modo e vivências de indivíduos que se identificam com os atributos sociais e sexuais que desviam do gênero designado ao nascer. O processo transexualizador é um programa que compõe a política de saúde brasileira e compreende um conjunto de estratégias de atenção à saúde, onde estão incluídos procedimentos de diferentes graus de complexidade para o processo de transformação de indivíduos transexuais. Objetivo: Caracterizar o perfil dos usuários de um serviço de referência, os números produzidos pelo serviço e as principais demandas relativas ao processo transexualizador. Metodologia: Trata-se de um estudo transversal, descritivo e exploratório. Os dados foram coletados através dos registros dos usuários que estão vinculados ao processo e dos procedimentos realizados pelo serviço. Resultados: Os dados coletados (N=180) indicam que parcela significativa é integrada por mulheres trans (66%). A maioria reside na região metropolitana do Recife (81%). Em relação à faixa etária, 65% estão entre 18 e 30 anos. Já foram realizadas Cinquenta e nove (59) cirurgias de trangenitalização em mulheres trans, dezesseis (16) implantes de próteses mamárias e dezessete (17) tireoplastia. Em homens trans, dezoito (18) realizaram mamoplastia masculinizadora e três (3) realizaram histerectomia. O serviço analisado é o único do Norte-Nordeste que oferece atendimento integral à pessoa trans e por isso a procura é alta e há um estrangulamento em atender às demandas. Atualmente existe uma lista de aproximadamente 580 pessoas na fila de espera.
Virtual Exhibition of PGMI IAIN Ambon Students Through Technical Assistance and Procedures for Exhibiting Fine Artwork During the Covid-19 Pandemic
Authors: Intan Candra Iga Ayu 
Published: March 2022

Abstract: The Covid-19 pandemic has interrupted the artistic process that occurs in society. Making people forced to use digital platforms in the process of expression and appreciation of art. During the Covid-19 pandemic, fine arts chose digital media as a way out for the exhibition. This community service is one solution to increase the expression and appreciation of PGMI IAIN Ambon students who will later teach art as classroom teachers. The service activity with the title "Virtual Exhibition of PGMI IAIN Ambon Students Through Technical Assistance in Crafting and Procedures for Exhibiting Fine Artwork During the Covid-19 Pandemic" seeks to create students who are aware of the values of artistic and are able to create works of art. Activities are carried out through a process of assisting work and assisting the process of implementing virtual exhibitions.Keywords: fine art, exhibition, virtual, covid-19Abstrak: Pandemi Covid -19 telah memutus proses kesenian yang terjadi di masyarakat. Membuat masyarakat terpaksa menggunakan platform digital dalam proses ekspresi dan apresiasi seni. Seni rupa pada masa pandemi Covid-19 memilih media digital sebagai jalan keluar pelaksanaan pameran. Pengabdian masyarakat ini merupakan salah satu solusi untuk meningkatkan ekspresi dan apresiasi mahasiswa PGMI IAIN Ambon yang nantinya akan mengajar seni sebagai guru kelas. Kegiatan pengabdian dengan judul kegiatan “ Pameran Virtual Mahasiswa PGMI IAIN Ambon Melalui Pendampingan Teknik Berkarya dan Prosedur Memamerkan Hasil Karya Seni Rupa Selama Pandemi Covid-19” berupaya mewujudkan mahasiswa yang sadar akan nilai-nilai keindahan dan mampu menciptakan karya seni rupa. Kegiatan dilaksanakan melalui proses pendampingan berkarya dan pendampingan proses pelaksanaan pameran secara virtual.Kata kunci: seni rupa, pameran, virtual, covid-19
Website Optimization of Digital Literacy Based Media Services
Authors: Kasim Eman Wahyudi 
Published: March 2022

Abstract: The development of science and technology today cannot be separated from the progress of internet services that are getting better and more comprehensive. This must be used optimally to encourage the creation of a superior and productive generation such as supporting the national literacy movement in the campus environment through community service activities. Service activities in the form of optimizing website-based student literacy media are expected to be a solution to support the literacy movement in the IAIN Ambon campus, especially in the Madrasah Ibtidaiyah Teacher Education study program. In addition, the existence of website-based literacy media can be a place to actualize students' ideas or ideas in a quality work. Keywords: Media,Literacy,Website
Pemodelan Suspensi Kendaraan Dalam Tinjauan Multi Derajat Kebebasan
Authors: Nugroho Pipit Wahyu , Muzaki Mochamad 
Published: April 2022

The two most important parameters in vehicle vibration are the level of comfort and stability. To get the best value from that parameter, the vehicle suspension system is very important to reduce vibration due to road waves and keep the wheels attached to the road. This paper studied the effect of the type of suspension on the vibration of a one-wheeled vehicle in terms of comfort and stability. The type of suspension is related to the value of the spring stiffness and the damping. While the vehicle is modeled with one wheel in two degrees of freedom. The test is carried out by loading the vehicle including the mass of the vehicle and passengers for each type of suspension, namely soft, medium and hard. Vibration analysis was performed using Matlab Simulink to obtain the acceleration response and deflection response. The vibration response graph shows the comparison of the level of comfort and stability of the vehicle on the road profile modeled in step, impulse and sinusoidal functions. From the simulation results, it is found that the Soft and Medium Suspension can handle vibration very well, especially from the level of response speed for relatively flat roads. Meanwhile, the Hard type of suspension is very good at dampening vibrations for high bumpy roads.
Rancang Bangun Aplikasi Latihan Fisik untuk Pemain Basket
Authors: Suwarno Suwarno , Derrick Derrick 
Published: March 2022

Kebugaran fisik adalah salah satu faktor penting bagi seorang pemain basket. Karena olahraga basket adalah salah satu olahraga yang memiliki banyak fisik kontak dengan pemain lain. Oleh karena itu, pemain basket diwajibkan memiliki tingkat kebugaran fisik yang bagus melalui latihan fisik yang teratur dan bisa dimonitor. Pada penelitian ini merancang bangun aplikasi berbasis Android physical workout atau latihan fisik untuk pemain basket dengan menggunakan metode Software Development Life Cycle (SDLC) Waterfall method dan pengujian aplikasi dengan algoritma backtracking. Aplikasi latihan fisik telah membantu pemain basket dalam menjaga kebugaran fisik dengan menunjukkan jenis latihan fisik dan jadwal yang teratur, cara latihan fisik yang benar, menghitung jumlah air yang dikonsumsi, dan menghitung persentase lemak tubuh.
Characterization and Validation of ceRNA-Mediated Pathway–Pathway Crosstalk Networks Across Eight Major Cardiovascular Diseases
Authors: Song Chao , Zhang Jian , Liu Yongsheng , Hu Yinling , Feng Chenchen , Shi Pilong , Zhang Yuexin , Wang Lixin , Xie Yawen , Zhang Meitian , Zhao Xilong , Cao Yonggang , Li Chunquan , Sun Hongli 
Published: April 2022

Pathway analysis is considered as an important strategy to reveal the underlying mechanisms of diseases. Pathways that are involved in crosstalk can regulate each other and co-regulate downstream biological processes. Furthermore, some genes in the pathways can function with other genes via the relationship of the competing endogenous RNA (ceRNA) mechanism, which has also been demonstrated to play key roles in cellular biology. However, the comprehensive analysis of ceRNA-mediated pathway crosstalk is lacking. Here, we constructed the landscape of the ceRNA-mediated pathway–pathway crosstalk of eight major cardiovascular diseases (CVDs) based on sequencing data from ∼2,800 samples. Some common features shared by numerous CVDs were uncovered. A fraction of the pathway–pathway crosstalk was conserved in multiple CVDs and a core pathway–pathway crosstalk network was identified, suggesting the similarity of pathway–pathway crosstalk among CVDs. Experimental evidence also demonstrated that the pathway crosstalk was functioned in CVDs. We split all hub pathways of each pathway–pathway crosstalk network into three categories, namely, common hubs, differential hubs, and specific hubs, which could highlight the common or specific biological mechanisms. Importantly, after a comparison analysis of the hub pathways of networks, ∼480 hub pathway-induced common modules were identified to exert functions in CVDs broadly. Moreover, we performed a random walk algorithm on the hub pathway-induced sub-network and identified 23 potentially novel CVD-related pathways. In summary, our study revealed the potential molecular regulatory mechanisms of ceRNA crosstalk in pathway–pathway crosstalk levels and provided a novel routine to investigate the pathway–pathway crosstalk in cardiology. All CVD pathway–pathway crosstalks are provided in http://www.licpathway.net/cepathway/index.html.
A Single-Nucleotide Polymorphism in the Promoter of Porcine ARHGAP24 Gene Regulates Aggressive Behavior of Weaned Pigs After Mixing by Affecting the Binding of Transcription Factor p53
Authors: Xu Qinglei , Zhao Jing , Guo Yanli , Liu Mingzheng , Schinckel Allan P. , Zhou Bo 
Published: April 2022

Pigs are important biomedical model animals for the study of human neurological diseases. Similar to human aggressive behavior in children and adolescents, weaned pigs also show more aggressive behavior after mixing, which has negative effects on animal welfare and growth performance. The identification of functional single-nucleotide polymorphisms (SNPs) related to the aggressive behavior of pigs would provide valuable molecular markers of the aggressive behavioral trait for genetic improvement program. The Rho GTPase–activating protein 24 (ARHGAP24) gene plays an important role in regulating the process of axon guidance, which may impact the aggressive behavior of pigs. By resequencing the entire coding region, partially adjacent introns and the 5′ and 3′ flanking regions, six and four SNPs were identified in the 5′ flanking region and 5′ untranslated region (UTR) of the porcine ARHGAP24 gene, respectively. Association analyses revealed that nine SNPs were significantly associated with aggressive behavioral traits (p = &lt; 1.00 × 10–4–4.51 × 10–2), and their haplotypes were significantly associated with aggressive behavior (p = &lt; 1.00 × 10–4–2.99 × 10–2). The core promoter region of the ARHGAP24 gene has been identified between −670 and −1,113 bp. Furthermore, the luciferase activity of allele A of rs335052970 was significantly less than that of allele G, suggesting that the transcriptional activity of the ARHGAP24 gene was inhibited by allele A of rs335052970. It was identified that the transcription factor p53 bound to the transcription factor binding sites (TFBSs) containing allele A of rs335052970. In porcine primary neural cells, p53 binds to the target promoter region of the ARHGAP24 gene, reduces its promoter transcriptional activity, and then reduces its messenger RNA (mRNA) and protein expression. The results demonstrated that the ARHGAP24 gene had significant genetic effects on aggressive behavioral traits of pigs. Therefore, rs335052970 in the ARHGAP24 gene can be used as a molecular marker to select the less aggressive pigs.