bluuebunny/crossref_metadata_2025_split huggingface dataset:
Binocular Metamorphopsia in Patients with Branch Retinal Vein Occlusion: A Multi- Center Study
Authors: Osaka Rie , Muraoka Yuki , Nagasato Daisuke , Mitamura Yoshinori , Nishigori Naomi , Murakami Tomoaki , Suzuma Kiyoshi , Tabuchi Hitoshi , Tsujikawa Akitaka 
Published: July 2022

Abstract
Purpose: The pathology of branch retinal vein occlusion (BRVO), a retinal circulatory disease, is related to monocular metamorphopsia-related vision impairment of the affected eyes, but the association of binocular metamorphopsia in such patients is unclear. This study aimed to examine the frequency of binocular metamorphopsia and its association with the clinical characteristics of patients with BRVO. Methods: A total of 99 patients who were treated for BRVO-associated macular edema (ME) were included in this study. At baseline and 1 and 3 months after the initiation of anti-vascular endothelial growth factor (VEGF) treatment, we quantified metamorphopsia in the affected eyes and binocular metamorphopsia using the M-CHARTS® diagnostic tool. Results: At baseline, 59 and 10 patients had metamorphopsia in the affected eyes and binocular metamorphopsia, respectively. Although the visual acuity improved significantly after the initiation of anti-VEGF treatment, the mean M-CHARTS score in the affected eyes did not change from the baseline score. At 3 months, 13 patients showed binocular metamorphopsia; it was significantly associated with metamorphopsia in the affected eyes with a 95% confidence interval of 0.037–0.172 (β = 0.305, p = 0.003). Conclusion: Metamorphopsia in the affected eyes can cause binocular metamorphopsia in patients with BRVO-ME.
Position-wise optimizer: A nature-inspired optimization algorithm
Authors: Valizadeh Amir 
Published: July 2022

Abstract
The human nervous system utilizes synaptic plasticity to solve optimization problems. Previous studies have tried to add the plasticity factor to the training process of artificial neural networks, but most of those models require complex external control over the network or complex novel rules. In this manuscript, a novel nature-inspired optimization algorithm is introduced that imitates biological neural plasticity. Furthermore, the model is tested on three datasets and the results are compared with gradient descent optimization.
Revisiting Statistics and Evidence-Based Medicine: On the Fallacy of the Effect Size Based on Correlation and Misconception of Contingency Tables
Authors: Roussakow Sergey 
Published: July 2022

Abstract
BACKGROUND: Evidence-based medicine (EBM) is in crisis, in part due to bad methods, which are understood as misuse of statistics that is considered correct in itself. The study questions the correctness of the basic statistics related to the effect size (ES) based on correlation (CBES). METHODS: Monte Carlo simulation of paired samples, mathematical analysis, conceptual analysis, bias analysis. RESULTS: Correlation and ES are not related. CBES is a fallacy, mainly based on the point biserial correlation (PBC) fallacy and misconception of contingency tables (MCT), which makes no distinction between gross crosstabs (GCTs) and contingency tables (CTs). Misapplication of Pearson’s correlation coefficient to point biserial datasets and GCTs gives ES parameters that are not related to correlation. Equations directly expressing ES in terms of correlation coefficient are flawed, since it is impossible without including covariance. Generalization of these fallacies leads to erroneous inferences, conversions, transformations, meta-analyses, and misunderstanding of the nature of correlation. MCT leads to misuse of the relevant statistics and is so ubiquitous that all findings from CTs are suspect. CONCLUSIONS: Two related common statistical misconceptions, CBES and MCT, have been exposed and fixed. These misconceptions are threatening because most of the findings from correlation, paired samples and CTs, including meta-analyses, can be misleading. Since exposing these fallacies casts doubt on the reliability of the statistical foundations of EBM in general, we urgently need to revise them.
benefícios do aleitamento materno em Unidade de Terapia Intensiva Neonatal: uma revisão de literatura.
Authors: Moraes Suellen Rocha , Souza Alessandra da Silva , Silva Jannaina Sther Leite Godinho , Silva Eliara Adelino da , Gomes Elisângela do Nascimento Fernandes , Ricci Adiel Queiroz 
Published: July 2022

Este estudo teve como objetivo identificar fatores que não contribuem para aleitamento materno efetivo, a promoção à adesão do aleitamento materno e os benefícios que o AM em Unidade de Terapia Intensiva Neonatal (UTIN). Trata-se de um estudo qualitativo, exploratório descritivo que foi realizado através de uma revisão integrativa de literatura, com intuito de esclarecer os benefícios do aleitamento, identificar estratégias que auxiliam na promoção do aleitamento materno (AM), e identificar fatores que não efetivam essa prática em unidades neonatais. Os resultados mostraram que os benefícios do AM auxiliam no desenvolvimento elo mãe e filho e no desenvolvimento psiquico do RN, além de fatores nutricionais, fisiológicos, biológicos e imunológicos. O principal fator que não contribuí para AM é a separação mãe/filho, o contato físico é primordial para efetividade dessa prática. Em relação a promoção do aleitamento materno, a educação permanente, escuta qualificada, aplicabilidade de estratégias, como por exemplo o Método Mãe Canguru, acesso dos pais ao Recém-nascido Prematuro (RNP), através de flexibilização da rotina, são fatores primordiais para promoção e adesão dessa prática. Através da identificação dos fatores é possível traçar estratégias a fim de promover o aleitamento e prevenir motivos que impeçam a aplicabilidade desse método.
Palavras-Chave: Aleitamento Materno; Nascimento Prematuro; Recém-nascido.
Electronic Patient Portal Access, Retention in Care, and Viral Suppression Among People Living With HIV in Southeastern United States: Observational Study
Authors: Schember Cassandra Oliver , Scott Sarah E , Jenkins Cathy A , Rebeiro Peter F , Turner Megan , Furukawa Sally S , Bofill Carmen , Yan Zhou , Jackson Gretchen P , Pettit April C 
Published: July 2022

Background
Approximately 1.1 million people living with HIV live in the United States, and the incidence is highest in Southeastern United States. Electronic patient portal prevalence is increasing and can improve engagement in primary medical care. Retention in care and viral suppression—measures of engagement in HIV care—are associated with decreased HIV transmission, morbidity, and mortality.

Objective
We aimed to determine if patient portal access among people living with HIV was associated with retention and viral suppression.

Methods
We conducted an observational cohort study among people living with HIV in care at the Vanderbilt Comprehensive Care Clinic (Nashville, Tennessee) from 2011-2016. Individual access was defined as patient portal account registration at any point in the year prior. Retention was defined as ≥2 kept appointments or HIV lab measurements ≥3 months apart within a 12-month period. Viral suppression was defined as the last viral load in the calendar year <200 copies/mL. We calculated adjusted prevalence ratios (aPRs) and 95% CIs using modified Poisson regression with generalized estimating equations to estimate the association of portal access with retention and viral suppression.

Results
We included 4237 people living with HIV contributing 16,951 person-years of follow-up (median 5, IQR 3-5 person-years). The median age was 43 (IQR 33-50) years. Of the 4237 people living with HIV, 78.1% (n=4237) were male, 40.8% (n=1727) were Black non-Hispanic, and 56.5% (n=2395) had access. Access was independently associated with retention (aPR 1.13, 95% CI 1.10-1.17) and viral suppression (aPR 1.18, 95% CI 1.14-1.22).

Conclusions
In this population, patient portal access was associated with retention and viral suppression. Future prospective studies should assess the impact of increasing portal access among people living with HIV on these HIV outcomes.
System Usability Scale Benchmarking for Digital Health Apps: Meta-analysis
Authors: Hyzy Maciej , Bond Raymond , Mulvenna Maurice , Bai Lu , Dix Alan , Leigh Simon , Hunt Sophie 
Published: July 2022

Background
The System Usability Scale (SUS) is a widely used scale that has been used to quantify the usability of many software and hardware products. However, the SUS was not specifically designed to evaluate mobile apps, or in particular digital health apps (DHAs).

Objective
The aim of this study was to examine whether the widely used SUS distribution for benchmarking (mean 68, SD 12.5) can be used to reliably assess the usability of DHAs.

Methods
A search of the literature was performed using the ACM Digital Library, IEEE Xplore, CORE, PubMed, and Google Scholar databases to identify SUS scores related to the usability of DHAs for meta-analysis. This study included papers that published the SUS scores of the evaluated DHAs from 2011 to 2021 to get a 10-year representation. In total, 117 SUS scores for 114 DHAs were identified. R Studio and the R programming language were used to model the DHA SUS distribution, with a 1-sample, 2-tailed t test used to compare this distribution with the standard SUS distribution.

Results
The mean SUS score when all the collected apps were included was 76.64 (SD 15.12); however, this distribution exhibited asymmetrical skewness (–0.52) and was not normally distributed according to Shapiro-Wilk test (P=.002). The mean SUS score for “physical activity” apps was 83.28 (SD 12.39) and drove the skewness. Hence, the mean SUS score for all collected apps excluding “physical activity” apps was 68.05 (SD 14.05). A 1-sample, 2-tailed t test indicated that this health app SUS distribution was not statistically significantly different from the standard SUS distribution (P=.98).

Conclusions
This study concludes that the SUS and the widely accepted benchmark of a mean SUS score of 68 (SD 12.5) are suitable for evaluating the usability of DHAs. We speculate as to why physical activity apps received higher SUS scores than expected. A template for reporting mean SUS scores to facilitate meta-analysis is proposed, together with future work that could be done to further examine the SUS benchmark scores for DHAs.
Long-Term Effect of Physical Exercise on the Risk for Hospitalization and Death in Dialysis Patients
Authors: Mallamaci Francesca , D’Arrigo Graziella , Tripepi Giovanni , Lamberti Nicola , Torino Claudia , Manfredini Fabio , Zoccali Carmine 
Published: July 2022

Background and objectives
In the EXerCise Introduction to Enhance Performance in Dialysis (EXCITE) trial, a simple, personalized 6-month walking exercise program at home during the day off of dialysis improved the functional status and the risk for hospitalization in patients with kidney failure. In this post-trial observational study, we tested whether the same intervention was associated with a lower long-term risk of death or hospitalization (combined end point) during a follow-up extended up to 36 months.

Design, setting, participants, & measurements
In total, 227 patients (exercise, n=104; control, n=123) completed the 6-month trial and entered the post-trial observational study. Data were analyzed by unadjusted and adjusted Cox regression analyses and Bayesian analysis.

Results
In the long-term observation (up to 36 months), 134 events were recorded (eight deaths not preceded by hospitalization and 126 hospitalizations, which were followed by death in 38 cases). The long-term risk for hospitalization or death was 29% lower (hazard ratio, 0.71; 95% confidence interval, 0.50 to 1.00), and in an analysis stratified by adherence to the walking exercise program during the 6-month trial, the subgroup with high adherence (>60% of prescribed sessions) had a 45% lower risk as compared with the control group (hazard ratio, 0.55; 95% confidence interval, 0.35 to 0.87). A Bayesian analysis showed that the posterior probability of a hazard ratio of 0.71 (95% confidence interval, 0.50 to 1.00) for the risk of the composite outcome observed in the post-trial observational study was 93% under the conservative prior and 97% under the optimistic prior. Sensitivity analyses restricted to the risk of hospitalization only or censoring patients at the time of transplantation fully confirmed these findings.

Conclusions
A simple, personalized, home-based, low-intensity exercise program was associated with a lower risk of hospitalization.

Clinical Trial registry name and registration number:
EXerCise Introduction to Enhance Performance in Dialysis (EXCITE), NCT01255969
Lisdexamfetamine is an effective monotherapy for moderate to severe binge eating disorder
Authors: Young Benjamin 
Published: July 2022

A clinical decision report using:
McElroy SL, Hudson J, Ferreira-Cornwell MC, Radewonuk J, Whitaker T, Gasior M. Lisdexamfetamine dimesylate for adults with moderate to severe binge eating disorder: Results of two pivotal phase 3 randomized controlled trials. Neuropsychopharmacology. 2016;41(5):1251-1260. https://doi.org/10.1038/npp.2015.275
for a young woman requesting a novel pharmacological intervention for a Binge Eating Disorder (BED).
Consistent Effects of Hypoglycemia on Cognitive Function in People With or Without Diabetes
Authors: Verhulst Clementine E.M. , Fabricius Therese W. , Nefs Giesje , Kessels Roy P.C. , Pouwer Frans , Teerenstra Steven , Tack Cees J. , Broadley Melanie M. , Kristensen Peter L. , McCrimmon Rory J. , Heller Simon , Evans Mark L. , Pedersen-Bjergaard Ulrik , Galan Bastiaan E. de , consortium the Hypo-RESOLVE 
Published: July 2022

<p> </p>
<p><strong>OBJECTIVE</strong> Hypoglycemia poses an immediate threat for cognitive function. Due to its association with acute cognitive impairment, the International Hypoglycemia Study Group (IHSG) defines a blood glucose level <3.0 mmol/L as “level 2 hypoglycemia”. The present study investigated whether having diabetes, type of diabetes or hypoglycemia awareness moderates this association. </p>
<p><strong>RESEARCH DESIGN AND METHODS</strong> Adults with type 1 diabetes with normal (<em>n=</em>26) or impaired (<em>n=</em>21) hypoglycemic awareness, or with insulin-treated type 2 diabetes (<em>n=</em>15) and age-matched controls without diabetes (<em>n=</em>32) underwent a hyperinsulinemic-euglycemic hypoglycemic glucose clamp (2.80 ± 0.13 mmol/L [50.2 ± 2.3 mg/dL]). At baseline and during hypoglycemia, calculation ability, attention, working memory and cognitive flexibility were measured with the Paced Auditory Serial Addition Test (PASAT) and the Test of Attentional Performance (TAP). </p>
<p><strong>RESULTS</strong> For the whole group, hypoglycemia decreased the proportion of correct answers on the PASAT by 8.4 ± 12.8%, increased the mean reaction time on the TAP Alertness task by 32.1 ± 66.6 ms, and increased the sum of errors and omissions on the TAP Working Memory task by 2.0 ± 5.5 (all <em>p </em>< 0.001). Hypoglycemia-induced cognitive declines were largely irrespective of the presence or type of diabetes, level of symptomatic awareness, diabetes duration or HbA1c.</p>
<p><strong>CONCLUSIONS </strong>IHSG level 2 hypoglycemia impairs cognitive function in people with and without diabetes, irrespective of type of diabetes or hypoglycemia awareness status. These findings support the cut-off value of hypoglycemia <3.0 mmol/L (<54 mg/dL) as being clinically relevant for most people with diabetes. </p>
<p><br></p>
Investigating Students’ Reading Habit in Learning English at Islamic Boarding Senior High School Babussalam Pekanbaru
Authors: Anggraini Suci , Bukhori Bukhori 
Published: July 2022

Reading habit refers to the behavior which expresses the likeness of reading of individual types of reading and tastes of reading (Sangkaeo 1999) cited in Chettri and Rout (2011). However, the students at the Eleventh Grade Students of Islamic Boarding Senior High School in Pekanbaru were not always go to the library to read books or may borrow books, but sometimes they go. This research wanted to describe the students’ reading habit. The design of this research is descriptive quantitative research. The population of the research was the eleventh grade of Islamic Boarding Senior High School in Pekanbaru and the sample were 26 students. The number of sample is selected by using simple random sampling technique. To get the data, the writer employed a close-ended questionnaire. The result showed that majority students at the eleventh grade of Islamic Boarding Senior High School in Pekanbaru had a good reading habit. Meanwhile, some of them showed that they have fair reading habit and of them don’t have good reading habit it is categorized as poor. It can be concluded that the students at the eleventh grade of Islamic Boarding Senior High School in Pekanbaru had various reading habit.
Automatic Knowledge Integration Method of English Translation Corpus Based on Kmeans Algorithm
Authors: Liang Ping , Al Bayatti Hilal 
Published: July 2022

Abstract
We propose a feature extraction method based on the Kmeans algorithm based on the text characteristics in the English translation corpus. The article first uses a sparse autoencoder unsupervised learning method to reduce dimensionality. It then uses the Kmeans clustering algorithm for text clustering. The experimental results prove that the text features extracted by the sparse autoencoder based on the Kmeans algorithm can be used for English translation corpus knowledge clustering to achieve automatic integration. And this method can effectively solve the problems of high-dimensional, sparse, and noisy texts in the English translation corpus. The algorithm mentioned in the article can significantly improve the accuracy of the clustering results.
PERFORMANCE MEASUREMENT BASED ON BALANCE SCORECARD PERSPECTIVE OF SUSTAINABLE LEADERSHIP, CORPORATE GOVERNANCE AND HUMAN CAPITAL IN BANKING INDUSTRY
Authors: Kusnanto Eri 
Published: July 2022

The purpose of this research was to testing the effect sustainable leadership, corporate governance and human capital on the measurement of company performance using the Balanced Scorecard of the banking industry. A sample of banking company employees with a questionnaire was taken and the data was collected using SEM to test the effect of each variable.
Sustainable leadership, corporate governance and the impact of human capital on performance measurement is considerable using a balanced scorecard but regarding the effect of test moderation, human capital has no moderating effect on sustainable leadership and corporate governance on performance measurement. The use of samples is still limited from several banking companies. Companies must pay attention to the development of sustainable human resources to increase the value of the company. Also use sustainable leadership components and synergies components in measuring the balance scorecard.
Inactive Women as a Result of The Gender-Based Division of Labor and a Solution Proposal: “VirtualCall Project”
Authors: IŞIK Ebru 
Published: July 2022

Today, many women are excluded from the labor market despite having a good education. Perhaps the most obvious reason for this situation is the gender-based division of labor. Because of this division of labor, women are mostly considered to be responsible for domestic work and care work and it becomes difficult for them to go out of the house.
Women who are not able to participate in the work life due to their domestic responsibilities and are not considered unemployed, currently considered as inactive. Economic inactivity, which is a huge problem for many European countries including Turkey, excludes a great potential human resource that will be productive for the economy if they work.
Many countries offer different solutions to solve the inactivity problem. The health crisis caused by the Covid 19 epidemic has also led people to work more flexibly and at home. “The VirtualCall Project”, which received grant support from the European Union, is one of these solution proposals.
The aims of this study are to draw attention to the economic inactivity problem of women, which is the result of the gender-based division of labor, and to introduce the VirtualCall Project, which is realized as a solution proposal. In line with this purpose, firstly economic inactivity will be defined then the division of labor based on gender will be mentioned, and solution suggestions will be put forward.
Search for new dimensions of the educational space: digital and non-digital vectors of development
Authors: Krotenko T. Yu. 
Published: July 2022

Sociocultural, ecological, economic circumstances in which the constantly changing world finds itself persistently demand the emergence of new directions and subjects of research in the educational sphere. The purpose of the article is to identify promising vectors for studying the space of lifelong education. The following research methods were used: a) analysis of a combination of terms that combine philosophical, socio-cultural, economic and educational meanings; b) analysis of the author’s pedagogical experience in the formats of formal, non-formal and spontaneous education; c) an expert survey conducted online in October 2021; d) content analysis of detailed answers to the questions offered to respondents. As a result, the article outlines previously not obvious sources for creating an interdisciplinary methodological basis, the appearance of which can be predicted at the junctions of various fields of knowledge, in practice-oriented research attempts to implement the ideas of transdisciplinarity. The author’s research diagnoses fundamentally new methodological impulses that exist in science and modern philosophy when considering continuous knowledge as a vital attribute of a modern person. The possibilities that are hidden in paradoxical, at first glance, combinations and at the intersections of previously completely independent knowledge spheres are discussed. This is important for solving the problem of preserving anthropic qualities, which is especially prominent in the course of the chaotic development of learning systems that integrate human nature and artificial intelligence. The scientific novelty of the work is made up of conclusions about research methods that are most suitable for the formation of new psychological and pedagogical knowledge about permanent education.
Technology Acceptance Model Untuk Analisis penerimaan Pengguna Manajemen Pembelajaran Berbasis Online"Google Classroom"Pada Masa Pandemi Covid-19
Authors: Utami Ardhini Warih , Fatrianto Dwi Fatrianto 
Published: July 2022

Pada saat ini diberbagai negara dibelahan bumi tengah dikejutkan dengan pemberitaan pandemi. Pandemi saat ini yang menjadi ketakutan penduduk dan pemerintah diseluruh dunia adalah pandemi virus corona. Melihat perkembangankasus pandemi Covid-19 yang ada Indonesia jumlahnya bertambah dan penyebaran virusnya semakin sulit dikendalikan,pemerintah pusat membuat kebijakan dalam upaya pencegahan pandemi covid-19 dengan pengaturan jarak sosial (socialdistancing) dan fisik(physical distancing) diberbagai lini kehidupan. Berdasar surat yang dikeluarkan oleh Mendikbud RI No.3 Tahun 2020 tentang pencegahan COVID-19 yang ada padasatuan pendidikan tinggi di Indonesia, yang menyatakan himbauan kepada seluruh pendidikan tinggi di seluruh Indonesiauntuk melakukan aktivitas belajar dari rumah. Menggunakan LMS Google Classroom merupakan salah satu solusi yang Anda butuhkan untuk mendukung proses pendidikan dan kegiatan belajar dalam jaringan (Daring) di masa pandemi Covid-19. Kegiatan LMS yang memanfaatkan Google Classroom selama pandemi covid-19 dapat meningkatkan fleksibilitasbelajar. Dengan kata lain, Anda dapat mengakses materi pembelajaran berulang kali setiap saat, semakin meningkatkanpembelajaran Anda terhadap materi pembelajaran. Hal itu diukur dengan model penerimaan teknologi untuk melihatbagaimana perasaan dan perilaku pengguna terhadap teknologi informasi yang digunakan selama pandemi Covid-19 untukkegiatan pembelajaran online.Kata Kunci— Technology Acceptance Model, Learning Management System, LMS, Coid-19, Daring, Belajar.