bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Compact Novel SE-DGS Tapered-Fed Notched UWB Antenna Integrated with Ku/K band for Breast Cancer Detection
Authors: Ponnapalli V L N Phani , Karthikeyan S , Narayana J Lakshmi , Devana V N Koteswara Rao 
Published: July 2022

Abstract

A compact and novel semi-elliptical defected ground structure (SE-DGS) tapered microstrip line fed UWB antenna with band notched characteristics integrated with Ku and K band applications is proposed. The proposed SE-DGS UWB antenna is printed on a compact size of (15×18 mm2) and has an impedance bandwidth of 4.11-29.77 GHz, a fractional bandwidth of 152%, and both the down link of X- and ITU-8 bands are completely notched over a span of 6.86-9.09 GHz using a single C-structured reflector. The proposed antenna has a fluctuating gain of 1.7–4.82 dBi except for the gain at the notched band frequency, which is -12.25 dBi. The proposed antenna has a high radiation efficiency of 96.23%, stable radiation patterns over the UWB range, and a high rejection capability of the notched band, which is noticed from the high value of VSWR of 23.15, making it a potential candidate for UWB, Ku, and K band wireless applications with effectively suppressed downlink of X and ITU-8 bands. The developed antenna design simulates breast cancer tissue detection by comparing S21 outcomes, current densities, and specific absorption rates with and without tumour scenarios. These results suggest that the proposed radiator and system detect breast tumours efficiently.
Time-delayed modelling of the COVID-19 dynamics with a convex incidence rate
Authors: Babasola Oluwatosin , Oshinubi Kayode , Peter Olumuyiwa James , Onwuegbuche Faithful Chiagoziem , Khan Ilyas 
Published: July 2022

Abstract
In this paper, we investigate the SEIR epidemic model with a convex incidence rate incorporated with a time delay. We first discussed the epidemic model as a form of a classical ordinary differential equation and then the inclusion of a delay to represent the period in which the susceptible and exposed individuals became infectious. Secondly, we identify the disease-free together with the endemic equilibrium state and examine their stability by adopting the delay differential equation stability theory. Thereafter, we carried out numerical simulations with suitable parameters choice to illustrate the theoretical result of the system and for a better understanding of the model dynamics. We also vary the length of the delay to illustrate the changes in the model as the delay parameters change which enables us to further gain an insight into the effect of the included delay in a dynamical system. The result confirms that the inclusion of delay destabilises the system and it forces the system to exhibit an oscillatory behaviour which leads to a period solution.
Synthesis and Structural Characterization of Two-dimensional Metal-organic Framework by Using Bent Ditopic Carboxylate Ligands
Authors: Zhong Wen-Wu , Firuzabadi Fahimeh Dehghani , Zeng Xue , Feng Yuan-Jiao , Liu Kuan-Guan , Morsali Ali , Retailleaf Pascal 
Published: July 2022

Abstract
To design and make new metal-organic frameworks with desired structure and consequently spatial properties, there need to choose both metal ion as a node and ligands as their linkers. In pillared metal-organic frameworks, the presence of two linkers make bifunctional MOFs. Here, a pillar two-dimensional metal-organic framework (MOF) with molecular formula [Zn(cba)(bpdb)].DMF (2DTMU-1) was obtained by the reaction of zinc(II) nitrate with 4,4'-methylenedibenzoic acid (H2cba) as the carboxylate linker and 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene (bpdb) as the N-donor pillar. The structure was determined by single-crystal X-ray diffraction and Fourier-transform infrared spectroscopy (FT-IR). 2DTMU-1 is based on a binuclear paddlewheel Zn(II) unit complexed by four bridging bidentate (dicarboxylate) V-shaped ligand, 4,4'-methylenedibenzoic acid (H2cba), this tetragonal array being connected by bpdb with a bridging azine group in the middle as a potential Lewis basic site, making two-dimensional metal-organic framework structure and shows a pore size of 18 × 12 Å2.
Health-related quality of life in parents of adolescents - A two-year longitudinal study
Authors: Rohde Gudrun , Helseth Sølvi , Skarstein Siv , Mikkelsen Hilde ET , Småstuen Milada Cvancarova , Haraldstad Kristin 
Published: July 2022

Abstract
Aim: For many adults, their role as a parent is a vital part of their life that may influence their health-related quality of life (HRQOL) and vary with the age of their child. The aim of the present study was to describe and compare sociodemographic and psychological factors, pain and HRQOL in parents of adolescents assessed at baseline and 2 years later and to quantify the possible impact of gender, sociodemographic and psychological factors and pain on changes in HRQOL over time. Methods: A longitudinal study of 309 parents from the general Norwegian population was conducted. We used data collected at baseline (T1), when the adolescents were aged 14–15 years (2018/2019), and two years later (T2), in 2021, when the COVID-19 pandemic was ongoing. HRQOL was assessed using RAND-36. Data were analysed using McNemar tests, paired samples t-tests and multiple linear regression analyses.Results: Of the participants, 82% were mothers and 18% fathers. From T1 to T2, the average pain score increased, 1.6 (95% CI [-1,4; 1.8]) vs 1.8 (95% CI [1,6; 2.0]), the pain interference emotion score increased, 1.6 (95% CI [1.3; 1.9]) vs 1.8 (95% CI [1.5; 2.1]), and a larger proportion reported pain duration >3 months (44% vs 50%, p = 0.014). The parents were more lonely, 12.8 (95% CI [12.3; 13.3]) vs 13.7 (95% CI [13.2; 14.2]), and reported lower RAND-36 mental component summary (MCS) scores, 52.2 (95% CI [51.3; 53.2]) vs 50.9 (95% CI [49.8; 52.0]). There were no significant associations between gender, sociodemographic factors, psychological factors, pain at T1 and changes in RAND-36 physical component summary (PCS). A positive change in MCS from T1 to T2 was predicted by working part time, B = 5.22 (95% CI [1.05; 9.38]) (ref no paid work) and older age, B = 0.24, (95%CI [-001; 0.42]), and there was a negative change with stress, B = -17.39, (95%CI [-27.42; -7.51]). Conclusion: The parents experienced more pain and were lonelier, and more reported reduced mental HRQOL. However, the changes appear to be of limited clinical significance, as the parents seemed to have resilience factors to cope, even during an ongoing pandemic.
Measurement and identification of generalised translational static stiffness in machining space of five-axis machine tool
Authors: Jastrzębska Joanna , Parus Arkadiusz , Jastrzębski Daniel , Pawełko Piotr 
Published: July 2022

Abstract
This work presents a measurement for the identification of translational quasi-static stiffness of machine tool using Stiffness Workspace System (SWS). The novelty of this work is a significant modification of the SWS. The changes in measurement procedure and data analysis as well as new technical solutions are described in detail. A methodology for generalised translational static stiffness determination is presented. The major purpose of this paper is to provide the information about quasi-static stiffness values that characterise a typical machine tool. The measurement procedure is implemented in a case study on a 5-axis machining centre. Measurement results were used to determine the generalised translational stiffness indicators of points in the workspace. Then, the static stiffness distribution on the XY plane over machining space was estimated. The obtained results confirm the importance of analyses of static stiffness distribution as they point out areas where some possible changes occur. In the conclusion of the paper the utility value of the information of translational static stiffness is emphasized.
Anti-cancer effect of recombinant PI-laterosporulin10 as a novel bacteriocin with selective cytotoxicity on triple negative breast cancer cells
Authors: Rafizadeh Bahare , Reiisi Somayeh , Saffar Behnaz , Taheri Forough , Farhadian Sadegh 
Published: July 2022

Abstract
Anti-microbial peptides (AMPs) are important factors of the innate immune system which perform a comprehensive spectrum of biological activities. The present study aims to examine the expression, purification, and cytotoxic effects of recombinant PI-laterosporulin10 (LS10) a defensing-like peptide. PI is a transmembrane peptide that helps to increase penetration and specificity of peptide targeting. PI-LS10 sequence was optimized and fused to a Xa protease site to achieve higher levels of expression. Then Xa-PI-LS10 was cloned into the pET-32a (+) vector and expressed in E. coli BL21 (DE3). The fusion protein with a molecular weight of about 25.3 kDa was analyzed using the SDS-PAGE. The maximum expression was observed 8 hours post-induction. After enzymatic cleavage, the purity of PI-LS10 was >300 µg/ ml as the final yield. The recombinant PI-LS10 showed anti-cancer characteristics against breast cancer cell lines. MCF7 (non-triple negative) and MDA-MB-231 (triple negative) cells were treated with different concentrations of the PI-LS10 in order to evaluate their cytotoxic activity and efficiency in targeting triple negative cells. Our results suggest that PI-LS10 had a significant cytotoxic effect against breast cancer cells in comparison to the normal cell line. Triple negative breast cancer cell (MDA-MB-231) proliferation inhibited higher in 72 hours after treatment compare MCF7 cells. In conclusion, the PI-LS10 peptide was produced successfully and its favorable anti-cancer activity against a breast cancer cell line was confirmed.
Topology and perception aware image vectorization
Authors: He Yuchen , Kang Sung Ha , Morel Jean-Michel 
Published: July 2022

Abstract
We propose a new color image vectorization method converting raster images to resolution-independent scalable vector graphics. Starting from a quantized raster image, the method builds a hierarchical structure to represent its discontinuity set. The lowest-level elements, called curve-elements separate exactly two colors, and end at T-junctions or X-junctions. The middle-level objects, called curvebases, are concatenations of curve-elements following perceptual rules and representing the apparent contours of objects. On the highest level, the jump set coincides with the discontinuity set of the quantized image input.A geometric filtering method removes pixelization effects by affine shortening of the curvebases while resolving the induced topological changes. All junctions are preserved, thus maintaining the highest level of perceptual fidelity even on tiny pixel art images. A single parameter controls the simplification of curves between two junctions.Theoretical bounds are given to guarantee the method's topological consistency. This allows the method to be iterated such that it yields a smoothing semi-group. In both qualitative and quantitative experiments, our method compares favourably to multiple state-of-art algorithms and software.
Zinc-solubilizing Pseudomonas strains accelerate the release of zinc from tire waste powder and improve maize growth and zinc nutrition
Authors: Nasirzadeh Azar , Hamidpour Mohsen , Abbaszadeh-Dahaji Payman , Akhgar Abdolreza , Kariman Khalil 
Published: July 2022

Abstract
The authors have requested that this preprint be removed from Research Square.
Synthesis of a New Hydrophobic Coating Film from Stearic Acid of Buffalo Fat as By-product
Authors: Soliman Hanaa , Abdel-Wahhab Mosaad , Zahran Hamdy 
Published: July 2022

Abstract
In this work, pure stearic acid had been isolated from buffalo adipose tissue, and chemically converted to a waxy stearyl stearate, which was then used as a coating film for enhancing the shelf life of freshly harvested fruits. Where adipose tissue was minced, fat was extracted by dry rendering method, and then it was characterized. The extracted fat was hydrolyzed into a mixture of free fatty acids and glycerol. Supercritical CO2 extractor was used for stearic acid individual extraction in pure form from the free fatty acids mixture, and it was confirmed according to its melting point, elemental analysis, GC-MS and mass spectrometry (MS) of the corresponding methyl ester. The isolated stearic acid was used for synthesis of a new hydrophobic wax named as stearyl stearate, the chemical structure of the prepared compound was established according to its elemental analysis and spectral data. The new hydrophobic wax was used as a coating film to enhance the shelf life of freshly harvested tomato fruit. Therefore, stearyl stearate solution (2.00% w/v diethyl ether) was used for tomato coating, and compared to chitosan-coated tomatoes, where, weight loss, pH, fruit firmness, ascorbic acid concentration and total soluble solids were studied for a period of 15 days at 23±1°C and 65 ± 2% relative humidity. A sensory evaluation of the coated tomatoes was carried out. And the results revealed that coating with stearyl stearate solution (2.00% w/v diethyl ether), could delay tomatoes ripening during 15 days storing at 23±1°C and 65 ± 2% relative humidity. On the other hand, acute oral toxicity of stearyl stearate was achieved using albino mice of 21–25 g body weight to determine its safety.
A laboratory experiment for real-time sound source localization using Microsoft Kinect for Xbox 360
Authors: Douaer Belgacem 
Published: July 2022

Abstract
Sound Source Localization (SSL) consists of estimating the position of an emitting sound source. Accurate SSL is an essential step in many research areas as well as practical applications in acoustic signal processing and wireless communications. The main contribution of this work is the simplification of the high performance of two-dimensional sound source localization (2D-SSL), in which only four microphones are required. Firstly, the Time Difference Of Arrival (TDOA) based method is applied to a linear array configuration of four acquisition USB microphones, which have been used in two pairs to mount the experimental setup. For each single pair, the Angle of Arrival (AOA) of the sound source is calculated. Then, the 2D-SSL is determined using the trigonometric identities. To implement such a schematic, we have used the microphone array incorporated into the Microsoft Kinect device to acquire sound waves in real-time. To validate the accuracy of our study, laboratory experiments of sound source localization at different sound intensity levels were performed. In terms of RMSE position, the experimental results indicate that the suggested solution can be used to accurately find a two-dimensional sound source location in the far-field.
Translation and psychometric evaluation of the Alberta Continuity of Services Scale for Mental Health
Authors: Agudelo-Hernández Felipe , Vélez-Botero Helena , Andrade Rodrigo Rojas 
Published: July 2022

Abstract
Introduction: The continuity of care and attention is considered as a process that involves an orderly attention, an uninterrupted movement of people among several elements of the system of provision of services. It does not exist enough evidence in terms of measurement instruments of this continuity in Latin America. Even globally it has been conceptualized that this matter has been abandoned repeatedly by the research teams, possibly due to the shortage of validated multidimensional measures and to the lack of studies designed to approach the inherent complexities of the service. Objective: describe the process of translation, cultural adaptation to Colombia, as well as the internal consistency and construct validity of the Alberta Continuity of Services Scale for Mental Health (ACSS-MH). Methods: This instrument was subdued to the evaluation of validity of the content by experts and this was applied to a rural population in a Colombian context. Were performed tests of internal consistency and construct validity for each of the parts of the scale. Results: Under the consensus of the expert, it is made changes on some items, looking for a better adaptability of the instrument to the linguistic characteristics of Spanish, without losing sight of the evaluation objective of each one of the items on the original questionnaire. The result of the analysis of part A converged in 5 components that explain the 69.69% of the variance with 24 Items; Similarly, the analysis of part B grouped 13 items into four components, which explain the 72.02% of the variance. Discussion: This scale could be implemented to improve the provision of mental health services in Latin American contexts, where continuity of care has presented significant difficulties.
Therapeutic evaluation of induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma with low-risk N stage -a multicenter retrospective study from non-endemic region of China
Authors: Zang Jian , Li Yan , Liu Qiufang , Zhu Yong , Luo Shanquan , Li Xiaohua , Wang Jianhua , Hou Bingxin , Su Ning , Zhao Lina , Shi Mei 
Published: July 2022

Abstract
Background
There are conflicting results regarding the role of IC in T3-4N0-1 NPC patients from endemic area of China. Therefore, it is worth verifying the consistency of study between endemic area and non-endemic area for NPC and providing treatment guidance for non-endemic NPCs. We conducted a multicenter real-world study to investigate the value of adding IC to CCRT for T3-4N0-1 NPC in Northwest of China.
Methods
Data was extracted in three hospitals from Northwest China between May 1, 2010 and August 30, 2018. The Kaplan-Meier method was used to estimate the endpoints, survival curves were compared using the log-rank test. Initial propensity matching was conducted with a 1:1 match of IC + CCRT to CCRT. The primary endpoint of this study was overall survival (OS).
Results
A total of 108 patients with staging T3-4N0-1 were included in this study. The median follow-up time was 50 months (range: 6-118 months). IC followed by CCRT had trend to improve OS compared with CCRT (89.5% vs.77.6%, HR:0.41, 95%CI:0.16–1.04, P = 0.100). After analysis of well-balanced propensity score-matched cohort, IC followed by CCRT provided superior OS than CCRT alone. Adjusted 4-year OS was 89.5% for IC followed by CCRT vs. 71.1% for CCRT (HR:0.30, 95%CI:0.11–0.80, P = 0.027). No significant differences were detected in side effects between two groups.
Conclusion
This study implied IC followed by CCRT improved OS in patients with T3-4N0-1M0 NPC from Northwest China compared with CCRT. However, prospective studies with large sample are warranted to confirm the result.
Knowledge and Incidence of Gender-Based Violence among Young Adults in the South-South Region of Nigeria: A Comparative Study
Authors: Ndep Antor Odu , Obidile Valentine Chidi , Akwafuo Sampson , Ekwebene Onyeka Chukwudalu , Azubike Chidozie Precious , Umechinedu Ray-Desmond , Obidile-Ikwegbu Lois Ezinne 
Published: July 2022

Abstract
Background: Gender-Based Violence (GBV) entails fundamental violation of human rights and a violence that occurs due to normative role expectations attributable to one’s gender. It also includes all activities that facilitate an unbalanced power distribution between genders. These acts are likely to result in physical, sexual or emotional suffering which is usually meted out directly or indirectly through deceit, seduction, threat, coercion or any other means on the victim with the aim of intimidating, punishing or humiliating them.Methodology: The study was carried out in Cross River and Akwa Ibom States, South-South Region of Nigeria. A community-based cross sectional and descriptive approach was used, incorporating qualitative and quantitative techniques. A total number of 426 copies of the questionnaire were administered to respondents by the research team. Analysis was performed on the received data from the questionnaires, using Statistical Package for Social Sciences software (SPSS).Results and Discussion: Majority of the respondents 343(83.1%) have heard about gender-based violence, with Radio/TV 214(51.8%) being the highest source of information. A greater population, 325(78.7%) accepted that maltreatment to a person on the basis of gender which can cause harm to him or her describes gender-based violence. The study further showed that 72.9% young adults could identify the various forms of gender-based violence. Analysis of responses revealed that 198(47.9%) young adults in the study area have experienced at least, one form of gender-based violence in their lifetime. Further analysis showed that physical violence 140(33.9%) and sexual violence 108(26.2%) were the most reported forms of gender-based violence experienced by respondents.Conclusion: The study showed a moderate knowledge of gender-based violence among young adults, since 72.9% could clearly describe the subject matter. Despite this good knowledge, there was a high 47.9% occurrence of gender-based violence in the study area which showed no statistically significant relationship when tested.
Screening saikosaponin d (ssd)-producing endophytic fungi from Bupleurum scorzonerifolium Willd
Authors: Cheng Yupeng , Liu Guangjie , Li Zhongmeng , Zhou Yongqiang , Gao Ning 
Published: July 2022

Abstract
Saikosaponin d (SSd) is an important bioactive compounds produced by traditional Chinese medicinal plant Bupleurum scorzonerifolium Willd and exhibits many effects, such as anti-tumor, anti-inflammation and immunomodulatory. Since endophytic fungi possess the natural capacity to produce the similar secondary metabolite to that of their host plants, they are promising as alternative sources of plant bioactive natural products. In this study, in order to search for SSd-producing strains, endophytes were isolated from B.scorzonerifolium and were authenticated by the ITS sequence analysis. The profile of metabolites present in the crude exacts was carried out by Ultra performance liquid chromatography time-of-flight mass spectrometry (UPLC/Q-TOF-MS) analysis. The results showed that two strains, CHS2 and CHS3 from B.scorzonerifolium could produce SSd by Ultra performance liquid chromatography time-of-flight mass spectrometry (UPLC/Q-TOF-MS) analysis, and the amount of SSd produced by strain CHS2 and CHS3 were about 2.17 and 2.40 µg/mL, respectively. CHS2 and CHS3 showed a close phylogenetic relationship to Fusarium oxysporum and Fusarium acuminatum, respectively. According to our concern, no endophytic fungi capable of producing SSd from B.scorzonerifolium have been found before. Our clear intention was to isolate and identify these endophytic fungi which produce important active secondary metabolites, so as to provide a feasible and more convenient way to meet the drug demand.