bluuebunny/crossref_metadata_2025_split huggingface dataset:
Awareness, knowledge, attitude, perception, and utilization of complementary and alternative medicines (CAMs) in the common population of Dammam, Saudi Arabia
Authors: Ahmad Wasim , Ahmad Ayaz , Hassan Yousif A. , Sivapalan Nisha , Daniel Shainy , Anna Ruby A. , Al-Shurfa Fatimah , Albaharnah Fatimah , Al-Hayyan Amjad 
Published: July 2022

Background:
Complementary and alternative medicine (CAM)/natural products/herbs are frequently used for therapeutic purposes as a homemade remedy in Saudi Arabia. The use of CAMs is rising globally. However, special attention or precaution should be paid when using CAMs along with other drugs.

Objective:
The current study aims to examine the perception, attitude, knowledge, and awareness of the general population about CAMs and their utilization.

Material and Methods:
A cross-sectional study was conducted in March 2020 in the Dammam region of Saudi Arabia. The study included both the gender participants of the general population of Dammam, Saudi Arabia. The questionnaire contains the following sections including socio-demographic data, knowledge, attitude, and behavior of participants related to CAMs, and the prevalence of CAMs utilization in Dammam.

Results:
Participants were closely sex-matched (male: 50.93% and female: 49.07%), consisting of 97.1% Saudis and only 2.9% expats. The response rate was 67%; out of 559 participants, only 375 participants completed the questionnaire. Approximately 53% of participants had some knowledge of CAMs. Mass media (media/web/internet, advertisement, and television (TV), academic education, and family friends/relative represented the main source of the CAMs information (50%, 8.8%, and 15.2%, respectively). Among 77.3% of the participants, one of their family members has used some form of CAMs earlier. 90% of the participants or their family members using CAMs reported that olive oil (95.7%), green tea (89.1%), thyme (85.3%), cinnamon bark (84.8%), star anise (84.5%), and black seeds (78.4%) were the most used CAMs. Participants used CAMs for cold (28.3%), cough (14%), constipation (11.97%), ease of menstruation (10.8%), diarrhea (9.87%), and fever (8.62%). Approximately 75% of participants did not observe any side effects. Only 1% of participants reported that the CAMs are not useful therapeutically whereas the majority of the participants reported them as very useful (32.7%), useful (45.5%), and good (20.7%).

Conclusion:
Current study demonstrates that there is a positive attitude and perception toward CAMs. It is influenced by their traditional use as well. However, a community awareness program is essential for the adverse effects of CAMs.
Mini-Review on the Efficacy and Safety of Pitavastatin
Authors: Ramadan Azza , Elnour Asim Ahmed 
Published: July 2022

Background:
Recently, a plethora of events have affected the statin arena such as muscle-induced myalgia, myopathy, myositis, rare rhabdomyolysis, and new-onset diabetes. The latest statin pitavastatin has emerged with descent stamina (optimum efficacy and improved safety).

Objective:
The objective of the current review is to explore the pros and cons of pitavastatin as a novel second-generation statin in terms of efficacy and safety that delineate its clinical utility.

Methods:
The review was conducted via EBSCO hosted Medline search (AL Ain University, UAE subscription) for relevant English written literature articles containing “pitavastatin” as the primary search term “pitavastatin and safety;” “pitavastatin and efficacy” and “pitavastatin and safety and randomized clinical trials;” and “pitavastatin and efficacy and randomized clinical trials.”

Results:
The number of articles containing the word “pitavastatin” as the primary search term used was (n = 901). The next retrieves MeSH term was “pitavastatin and safety” (n = 99) and then “pitavastatin and efficacy” (n = 132). Furthermore, narrowing down the search by adding study design terms revealed: “pitavastatin and safety and randomized clinical trials,” (n = 10) and “pitavastatin and efficacy and randomized clinical trials” (n = 13). Combining the two main searches (safety and efficacy) has yielded 23 items, of which 15 articles were satisfying the current mini-review criteria. The prominent efficacy of pitavastatin was depicted by the increase in high-dense lipoprotein cholesterol and a decrease in low-dense lipoprotein cholesterol as illustrated by the clinical trials in the results and discussions section. The safety was enlightened with a very low propensity to cause new-onset diabetes and a low tendency for statin-induced muscular adverse events.

Conclusion:
Pitavastatin might be suitable for patients with the acute coronary syndrome (ACS), metabolic syndrome, and patients with diabetes. We highly recommend rational individualization for the selection of statin, especially in patients with diabetes and/or with ACS.
Rapid Preparative Isolation of Cleistanthin A from the Leaves of Cleistanthus Collinus Using Reverse-Phase Flash Chromatography
Authors: Kumar S C Santosh , Raveendran R , Achari Kamsali Murali Mohan 
Published: July 2022

Introduction:
Cleistanthin A (CA) is an aryl naphthalene lignan, which has a potent anticancer activity by regulating the tumor microenvironment. The objective was to develop a new technique for the isolation of cleistanthin A from the acetone extract of Cleistanthus collinus utilizing reverse phase flash chromatography.

Materials and Methods:

Cleistanthus collinus leaves were shade dried, defatted using n-hexane and then macerated to obtain acetone extract which was further subjected to reverse phase flash chromatography for the isolation of cleistanthin A using the gradient mobile phase of 0.1% formic acid (v/v) in water and acetonitrile. Gradient elution of chromatographic run was performed for 80 min. The separated peaks that showed absorbance at λmax 254 nm were collected for the chemical characterization. Cell viability of the isolated cleistanthin A was studied on hepatocellular cancer cell line HePG2 and prostate cancer cell line PC3 using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay.

Results:
The chemical characteristics of the isolated compound cleistanthin A was further characterized using spectral techniques such as 1H and 13C nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FT-IR), and electron spray ionization-tandem mass spectrometry (ESI-MS/MS). Cleistanthin A has decreased the cell viability of the HePG2 cell line to 52.25% at 32 μg/ml and PC3 cell line to 51.82% at 16 μg/ml in a dose-dependent manner.

Conclusion:
Cleistanthin A was successfully isolated from the natural source using reverse phase flash chromatography and the MTT assay has shown that cleistanthin A has decreased the cell viability in both the HePG2 and PC3 cell lines in a dose-dependent manner.
Nurses’ knowledge in the early detection and management of acute kidney injury in selected referral hospitals in Rwanda
Authors: Dushimiyimana V. , Bahumura J. , Adejumo O. , Moreland P. , Chironda G. 
Published: July 2022

INTRODUCTION: Acute kidney injury (AKI) is a global health issue, and its prevalence is higher in low- and middle-income countries (LMICs). The knowledge of nurses in the early detection and management of AKI has rarely been explored in the current literature; thus, this study aims to assess the knowledge of nurses in the early detection and management of patients with AKI in Rwanda.
METHODS: A cross-sectional research design was implemented for this study. The study setting included selected referral hospitals in Kigali. A convenience sample of 165 nurses was obtained and data was collected using a self-administered questionnaire. Analyses were made using descriptive and inferential statistics in SPSS version 21.
RESULTS: Nurses' knowledge in the early detection and management of AKI was low. Receiving in-service training on AKI positively influenced their knowledge in the early detection (p-value= 0.049), whereas studying AKI in nursing school p-value = 0.035) and receiving in-service training on AKI (p-value= 0.008) were associated with knowledge of the management of AKI. CONCLUSION: AKI is a common and potentially life-threatening condition that prolongs hospital stay, increases resource utilization, and mortality risks. Nurses need to be more involved in the early identification and management of AKI as they mostly serve as frontline health care providers and their role of continuous patient monitoring.
Turner syndrome in childhood period – A case Report
Authors: Tuyishimire B. , Karangwa O. , Rutagarama F. , Ndatinya A. , Nsanzabaganwa C. , Mutesa L. 
Published: July 2022

INTRODUCTION: Turner syndrome is a frequent chromosome disorder characterized by short stature, gonadal dysgenesis and multisystem diseases associated with high morbidity and reduced life expectancyCASE: We reviewed an 18 month old patient who presented to the genetics unit at Rwanda Military Hospital (RMH), a tertiary healthcare facility, with a chief complaint of poor weight gain. She was born with a birth weight of 1.76kg and in the neonatal period, paediatricians had noticed dysmorphic features. At the first consultation at the RMH genetics unit, he weighed 5.2kg and was 64 cm tall. Physical examinations revealed some dysmorphic features, including hypertelorism, absent philtrum, short and webbed neck and large low set ears. Cytogenetic analysis showed the chromosomal formula of 45, X0.
CONCLUSION: ThepatientwasdiagnosedwithTurnersyndromebasedonthecytogeneticanalysis and managed with physiotherapy of stimulation and re-education that led to improvements.
Jinekolojik Kanserli Hastalarda Algılanan Stres ile Umut Düzeyi İlişkisinin Belirlenmesi
Authors: URAS Eşe , BEYDAĞ Kerime Derya 
Published: July 2022

Amaç: Bu araştırma, jinekolojik kanserli hastaların algıladıkları stres düzeyi ile umut düzeyi ilişkisini belirlemek amacıyla tanımlayıcı ve kesitsel olarak yapılmıştır.
Gereç ve Yöntem: Araştırma, Haziran-Ekim 2018 tarihleri arasında, bir tıp fakültesi hastanesinin kadın hastalıkları ve doğum kliniğinde yatarak ve radyasyon onkolojisi ünitesinde günübirlik tedavi gören 124 hasta ile yapılmıştır. Veriler “Algılanan Stres Ölçeği” (ASÖ) ve “Sürekli Umut Ölçeği” (SUÖ) ile elde edilmiştir. Verilerin analizinde Kruskal Wallis testi, Man Whitney U testi, sperman korelasyon testi ve lineer regresyon analizi kullanılmıştır.
Bulgular: ASÖ puan ortalaması 34.56 ± 8.27 ve SUÖ puan ortalaması 56.31 ± 7.80 olarak bulunmuştur. ASÖ ile SUÖ arasında negatif yönde orta düzeyde korelasyon bulunmuştur (p
PENYULUHAN GIZI, PEMANTAUAN TUMBUH KEMBANG DAN PEMBERIAN MAKANAN PADA BALITA
Authors: Br Sianturi Marta Imelda 
Published: July 2022

Latar belakang: Keadaan gizi yang baik merupakan salah satu faktor penting dalam upaya mencapai derajat kesehatan yang optimal. Namun, berbagai penyakit gangguan gizi dan gizi buruk akibat tidak baiknya mutu makanan maupun jumlah makanan yang tidak sesuai dengan kebutuhan tubuh masing-masing orang masih sering ditemukan diberbagai tempat di Indonesia. Rendahnya status gizi jelas berdampak pada kualitas sumber daya manusia. Status gizi masyarakat dapat diketahui melalui penilaian konsumsi pangannya berdasarkan data kuantitatif maupun kualitatif.
Tujuan Kegiatan ini bertujuan memberi motivasi serta informasi kepada orang tua yang memiliki balita tentang pentingnya pemenuhan gizi pada balita dan memberi motivasi kepada orang tua yang memiliki balita tentang pentingnya kesadaran dalam memperhatikan asupan kebutuhan anak.
Metode Metode yang digunakan yaitu dengan melibatkan masyarakat sebagai bentuk pemberdayaan seperti penyuluhan tentang gizi balita, pengukuran BB dan TB balita dan pemberian makanan tambahan kepada balita. Populasi pada kegiatan ini adalah orang tua yang memiliki anak balita di Desa Rumah Berastagi, Kecamatan Berastagi.
Hasil: Dari hasil pemantauan tumbuh kembang balita yaitu dengan tindakan pengukuran tinggi badan dan penimbangan berat badan diperoleh bahwa pertumbuhan balita mayoritas dalam kategori bagus atau baik.
Simpulan: Pemantauan tumbuh kembang balita dapat terus dilakukan olah ibu yang memiliki anak balita melalui kegiatan posyandu.

Kata kunci: Penyuluhan; Gizi; Tumbuh Kembang; Balita..
Nuevas interpretaciones del espacio a través de la supergráfica a mediados de los años 60. Espacios fílmicos vs. espacios arquitectónicos.
Authors: Grávalos Lacambra Ignacio 
Published: July 2022

A mediados de los años sesenta se produjo un cuestionamiento del espacio del movimiento moderno. Tanto desde posiciones contraculturales como desde el pop se ensayaron intervenciones tendentes a desmaterializar sus límites. La supergráfica se convirtió en una estrategia con la que poder escenificar todas estas transformaciones.

La filmografía de esos años recoge numerosos ejemplos que permitieron experimentar nuevas espacialidades a través de los tratamientos gráficos de las superficies arquitectónicas. Estas propuestas alimentaron el imaginario arquitectónico de una generación que introdujo alteraciones sustanciales en el espacio moderno. La comprensión de las producciones de lo real y lo ficticio, indistintamente, venían a integrar los modos de pensar el espacio, componiendo una tercera dimensión que no pertenecía exclusivamente ni a lo real ni a la ficción, sino al imaginario social. La construcción de la realidad, por tanto, estuvo influida y determinada en gran medida por las nuevas espacialidades cinematográficas.
Economic expediency of application of snow-melting installations in institutions of the penal system
Authors: Мамонов Р.А. , Воробьева И.В. , Торженова Т.В. 
Published: July 2022

В статье рассматриваются проблемы уборки снега на режимных территориях учреждений уголовно-исполнительной системы. В зимний период в учреждениях с небольшой территорией, особенно находящихся в черте крупных городов, возникает вопрос складирования иливывоза снега. Денежных средств, выделяемых на утилизацию твердых бытовых отходов, не остается на вывоз снега, поэтому цель исследования – повышение эффективности уборки снега в учреждениях и органах уголовно-исполнительной системы с ее экономическим обоснованием. В результате проведенной работы установлено, что наиболее рациональным является способ уборки снегаплавлением в ливневую канализацию. Научной новизной выступает методика расчета, с помощьюкоторой можно определить необходимый объем перетапливаемого снега, подобрать подходящуюдля учреждения снегоплавильную установку по производительности, рассчитать энергетические иэксплуатационные затраты. Сделаны выводы о целесообразности применения установок с замкну-тым технологическим циклом плавления снега, работающих на электрической энергии или под-ключаемых к системе отопления зданий учреждений.
The article analyzes the problems of snow removal in the restricted areas of penal systeminstitutions. In winter, in institutions with a small area, especially those located within the boundariesof large cities, the issue of storage or removal of snow arises. Funds allocated for the disposal of solidhousehold waste do not leave balances for the removal of snow, therefore the purpose of the study is toincrease the efficiency of snow removal in institutions and bodies of the penal system with its economicjustification. As a result of the work carried out, it was found that the most rational method is to removesnow by melting it into the storm water drain. The scientific novelty is the calculation method, with the helpof which it is possible to assess the required volume of melted snow, to select a snow-melting installationsuitable for the institution in terms of productivity, to calculate the energy and operating costs. Conclusionsare made about the advisability of using installations with a closed technological cycle of melting snow,operating on electric energy or connected to the heating system of buildings of penal institutions.
Prevalencia de la lactancia materna exclusiva durante el con-finamiento secundario a la pandemia por COVID-19 en lac-tantes nacidos en la Clínica Santa Bárbara, durante el periodo de abril a junio del 2020
Authors: Contreras Mora Elizabeth , Núñez Carrera Roberto , Erazo Carlos 
Published: July 2022

Introducción: La lactancia materna exclusiva (LME) disminuye la morbimortalidad en niños lactantes. La prevalencia de LME en Ecuador es de 58.4%. No existe información disponible de cómo las restricciones aplicadas por la pandemia por COVID-19 han impactado en los hábitos de LME, por lo que este estudio tiene como objetivo determinar la prevalencia de LME durante el periodo de confinamiento y sus factores asociados.
Métodos: El presente estudio longitudinal, fue realizado en la clínica “Santa Bárbara” de Quito-Ecuador, de abril a junio del 2020, con una muestra no probabilística de madres de lactantes de niños sanos. Se describe la edad, estado civil, instrucción, actividad laboral, controles prenatales, tipo de parto, prácticas perinatales, control del niño sano, consejería prenatal- postnatal y LME. La asociación se presenta como odds ratio.
Resultados: 114 participantes con LME del 54.4% (62 madres). La consejería prenatal fue un factor protector OR 0.458 (IC 95% 0.216 -0.97) P = 0.045 para la presencia de LME. El uso de sucedáneos de leche materna al alta fue un factor de riesgo para la pérdida de LME, OR 2.46 (IC 95% 1.12-5.42) P=0.025. Los problemas médicos del lactante fueron un factor de riesgo para la pérdida de LME, OR 5.92 (IC 95% 2.62-13.37) P<0.0001.
Conclusiones: Existe mayor abandono de la LME, a pesar del mayor tiempo de contacto entre madre e hijo. El abandono se produce dentro del primer mes de vida en el 65.3% de los casos y se asocia al uso de sucedáneos de leche materna en el momento del alta del recién nacido. Hay una asociación entre problemas médicos del lactante y abandono de LME.
Determinantes de la supervivencia neonatal entre los neonatos fallecidos entre 2014 a 2017 en Ecuador
Authors: Aguilar Molina Andrea Elizabeth , Rivera Guerra Silvana Soledad , Dueñas Espín Ivan Guillermo 
Published: July 2022

Introducción: La mortalidad neonatal es un indicador en salud pública. En Ecuador la tasa defunción neonatal es 6 por cada 1 000 nacidos vivos. El objetivo del presente estudio fue identificar los principales determinantes de mortalidad neonatal en los neonatos fallecidos entre los años 2014 a 2017 en el Ecuador.
Metodología: Es presente estudio es un análisis de base de datos nacional del Instituto Nacional de Estadística y Censos del Ecuador-INEC y del Ministerio de Salud Pública del Ecuador, que registra la mortalidad de neonatos fallecidos entre los años 2014 y 2017. Se evaluaron las variables prenatales, natales, posnatales y sociodemográficas y su asociación con la mortalidad, medida en días de supervivencia. Se estimó los cocientes de riesgo de muerte neonatal ajustados (Hazard Ratio [HR]) mediante modelos de riesgos proporcionales de Cox y regresión de Cox ponderada por probabilidad inversa.
Resultados: Se incluyeron en el estudio 2 893 recién nacidos, 1 380 (48%) fueron de sexo femenino; edad gestacional mediana (P25 a P75) al nacer: 31 (27 a 36) semanas. La mediana del tiempo de supervivencia en días de vida fue significativamente mayor por cada aumento en la puntuación de Apgar a los 5 minutos: 0.2 días para ≤ 4 puntos, 2 días para 5 puntos 2.9 días para 6 puntos, 3.1 días para 7 puntos, 3.8 días para 8 puntos, 4.4 días para 9 puntos y 5.5 días para 10 puntos. Después de ajustar por variables prenatales, natales, posnatales y sociodemográficas, el HR fue 32% (IC 95%: 27% a 37%) más alto por cada disminución en el Apgar de dos a tres puntos (P < 0.01).
Conclusiones: La valoración de APGAR a los 5 minutos predice la supervivencia de los neonatos, los mayores valores se asocian con más supervivencia. Los factores que incrementan el riesgo de mortalidad son la edad materna adolescente y añosa, la edad gestacional prematuro extremo, el peso bajo extremo, la presencia de malformaciones y asfixia neonatal. Los factores sociodemográficos fueron los nacimientos en instituciones de primer nivel y los neonatos nacidos en la zona 3 del Ecuador (Cotopaxi, Tungurahua, Chimborazo y Pastaza).
The Role of Virtual Communities on Consumer Purchase Decisions with Brand Equity as Mediating Variable
Authors: Rukaiyah St. 
Published: July 2022

This study aims to analyze the relationship between virtual communities variabel on consumer purchase decision with brand equity as mediating vaiable. The sample in this study was selected with the 100 respondent with Snowball sampling and data colletion with survey. This study uses the PLS method. Next is a hypothesis to test whether there is a relationship between virtual communities, brand equity, and purchasing decisions at PT. Hadji Kalla Toyota Makassar. The analytical tool used in this research is Partial Least Square (PLS). Research using WarpPLS 6.0 program. The result of this study state Virtual communities are established to significantly affect purchasing decisions; Virtual communities are proven to have a significant positive effect on brand equity; The Virtual Communities variable shows a solid and dominant influence on brand equity compared to other variables; This study has provided findings on the effect of Virtual Communities on purchasing decisions through brand equity. Virtual Communities will have a role in delivering information that can produce word of mouth and become a choice for prospective buyers to see reviews and the advantages of products. That can be a consideration for companies in developing their marketing strategies, especially in building customer loyalty to the brand.
The Serbian Shaw
Authors: Vlašković Ilić Biljana 
Published: July 2022

ABSTRACT
This article provides a close reading of the Serbian Pygmalion in order to show whether the text (especially Eliza’s lines) has retained or lost some of its vitality in the translation by Borivoje Nedić, one of the finest Serbian translators. The analysis shows that although most of the techniques used by Nedić are appropriate, different translation solutions in specific cases would be more adequate in conveying the play’s main notion that language reveals one’s social class and shapes one’s identity.
On Translating Bernard Shaw’s Arms and the Man in Bulgarian
Authors: Tchaprazov Stoyan 
Published: July 2022

ABSTRACT
Unlike many of Bernard Shaw’s more prominent plays, Arms and the Man, his only play with a Bulgarian connection, remained untranslated into Bulgarian for more than a century. In this article, the author highlights his and his co-translator’s experiences in translating the play into Bulgarian. The article focuses on the challenges of translating specific stylistic idiosyncrasies of the play, including cultural referents, unconventional syntax, and punctuation.
A Bibliography of Bernard Shaw’s Works in Japanese Translation in Memory of Masahiko Masumoto
Authors: Morikawa Hisashi , Oura Ryuichi 
Published: July 2022

ABSTRACT
This is a bibliography of Bernard Shaw’s works in Japanese translation. It was originally compiled by Masahiko Masumoto (1934–2006) and has been supplemented and updated by Ryuichi Oura. The list is preceded by an introduction that briefly traces a history of Shaw’s reception in Japan and outlines how Japanese translators have tried to solve some problems in translating Shaw, such as choosing suitable titles and transplanting dialects and swear words.
Bernard Shaw at the Brighton School of Art: A Lecture on “Art and Public Money”
Authors: Rodríguez Martín Gustavo A. 
Published: July 2022

ABSTRACT
Bernard Shaw delivered a lecture on “Art and Public Money” in March 1907 at the annual prize-giving of the Brighton School of Art. This lecture remains one of the most popular sources for Shaw’s views on these subjects, especially because of his brilliant rhetoric and unmistakably Shavian style. The purpose of this article is to provide a critical edition of the text of the lecture, as reported by the Sussex Daily News and the Brighton Herald.