bluuebunny/crossref_metadata_2025_split huggingface dataset:
Which quality determinants cause MOOCs continuance intention? A hybrid extending the expectation-confirmation model with learning engagement and information systems success
Authors: Cheng Yung-Ming 
Published: May 2022

PurposeThe purpose of this study is to propose the research model integrating the expectation-confirmation model with the views of learning engagement (LE) and extending DeLone and McLean information systems (IS) success model to examine whether quality determinants as antecedents to students' beliefs can influence students' continuance intention of massive open online courses (MOOCs).Design/methodology/approachSample data for this study were collected from students enrolled in a comprehensive university in Taiwan. A total of 600 questionnaires were distributed, and 363 (60.5%) useable questionnaires were analyzed using structural equation modeling in this study.FindingsThis study proved that students' perceived knowledge quality, system quality, interface design quality, learner–instructor interaction quality, and collaboration quality all positively caused students' perceived usefulness, confirmation and LE in MOOCs, which jointly explained students' satisfaction with MOOCs and subsequently resulted in students' continuance intention of MOOCs.Originality/valueThis study fully evaluates IS-related and interaction-related quality determinants via an understanding of students' state of LE in explaining students' continuance intention of MOOCs that is difficult to expound with only their utilitarian perception of MOOCs. Hence, this study contributes to deep insights into an all-round quality evaluation in the field of MOOCs continuance intention and takes extrinsic and intrinsic motivators into account in the theoretical development of MOOCs continuance intention to acquire a more comprehensive and robust analysis.
Audit demand and monitoring mechanisms: evidence from SEC comment letters and short sellers
Authors: Skomra Justyna , Alam Pervaiz , Skomra Piotr Antoni 
Published: May 2022

Purpose
The paper aims to explore the impact of two types of monitoring mechanisms, namely, Securities and Exchange Commission (SEC) comment letters (CLs) and short sellers, on management’s demand for audit quality.

Design/methodology/approach
Using information on the short interest positions and a panel data of SEC CLs between 2005 and 2015, this study applies logit regression model to estimate the likelihood of hiring Big 4 and industry expert audit firm. This study also applies an ordinary least squares regression technique to estimate audit fees.

Findings
Consistent with disclosure and agency theories, results from empirical analyses provide that management demands higher quality audits measured by higher audit fees, and higher likelihood to hire Big 4 and industry expert audit firm. However, this study finds that the effect varies depending on the specific monitoring mechanisms. Additionally, when both monitoring mechanisms are in place, the SEC CLs drive the overall direction of the demand for audit quality when audit demand is captured by propensity to hire Big 4/industry expert audit firm.

Research limitations/implications
This study provides researchers with enhanced understanding of the factors having effect on the demand side for audit quality. Furthermore, it adds to the stream of literature on economic consequences of SEC CLs and short selling.

Originality/value
To the best of authors’ knowledge, this is the first comprehensive study to document the effect of two types of monitoring mechanisms, namely, SEC CLs and short selling, on the demand for audit quality.
Individual outcomes of employee resource group membership
Authors: Beaver Gregory Robert 
Published: May 2022

PurposeThis article illustrates the experiences of employee resource group (ERG) members over a two-year period with the aim of understanding the benefits and risks of membership for sexual minority employees.Design/methodology/approachQualitative interview data were collected from seven lesbian, gay or bisexual ERG members following an extreme case approach at two points in time separated by two years.FindingsThree themes of outcomes related to ERG membership emerged from the data. Participants reported both benefits and risks associated with the social and career-related consequences of membership. The role that allies play in providing visibility, legitimacy and support to ERG members also emerged and shifted in importance over the two years between interviews, with ally involvement becoming more important to career outcomes over time.Practical implicationsThis study illuminates potential consequences of supporting ERGs for minority employees, as well as insight into the role of allies in these groups.Originality/valueThis study contributes to the literature by revealing several individual outcomes of a growing form of diversity management practice: ERGs.
Serving for thriving: a moderated mediation analysis of the relationship between servant leadership and thriving at work
Authors: Jang Soebin , Yoo Sangok , Lee Jin , Lee Yunsoo 
Published: May 2022

PurposeDrawing on the socially embedded model of thriving at work, this study aims to test a moderated mediation model to elucidate the mediating effect of work meaningfulness and the moderating role of perceived interpersonal justice on the relationship between servant leadership and thriving at work.Design/methodology/approachBased on a sample of 221 employees from the manufacturing industry in South Korea, a series of hierarchical regression analyses were conducted by using statistical package for the social sciences (SPSS) software. For conducting moderated mediation analysis, the PROCESS macro for SPSS was utilized.FindingsThe findings show that servant leadership significantly relates to thriving at work, and work meaningfulness and perceived interpersonal justice act as a mediating mechanism and a boundary condition, respectively. Based on moderated mediation analysis, the collective effect of servant leadership, work meaningfulness and perceived interpersonal justice on thriving at work were also confirmed.Practical implicationsThe findings suggest that organizations should adopt servant leadership to promote employee thriving at work. In doing so, it is important to ensure that employees experience work meaningfulness, and are treated with respect and dignity.Originality/valueThis study extends research on servant leadership, and sheds light on important mechanisms and boundary conditions under which servant leadership promotes thriving at work.
Trust in the police and policing by consent in turbulent times
Authors: Torrible Clare 
Published: May 2022

Purpose
This paper aims to explore the potential impact on policing by consent and trust in the police of diminished political and generalised trust.

Design/methodology/approach
This paper draws on a range of academic literature on trust, the legal foundations of policing by consent, police occupational culture, disproportionality and neighbourhood policing.

Findings
An analytical framework is developed by recognising that policing by consent can be conceived as comprising two complementary facets, police state consent and police citizen consent and drawing lose mappings between police state consent and political trust and police citizen consent and generalised trust. This supports the argument that the importance of tackling disproportionality in policing practices and an increased emphasis on neighbourhood policing are not only valuable for reasons recognised in existing literature but also because they may bolster policing by consent in circumstances of reduced political trust and contribute to increased generalised trust across society.

Originality/value
This paper builds upon existing work on trust in the police and policing by consent to give novel insights into the importance of neighbourhood policing and tackling disproportionality. The analytical frame developed also highlights new areas for nuanced research questions in the field of trust and provides grounding from which policy objectives for policing can be developed.
Asymmetric effects of economic policy uncertainty on Bitcoin’s hedging power
Authors: Ali Md Hakim , Schinckus Christophe , Uddin Md Akther , Pahlevansharif Saeed 
Published: May 2022

Purpose
Even though Bitcoin has been often labelled as a safe haven asset class in the literature, the influence of economic policy uncertainty (EPU) on the diversifying opportunities offered by Bitcoin in relation to other assets needs to be investigated. This paper aims to investigate how the EPU affects diversification of commodity, conventional, Islamic and sustainable equity returns in relation to its impact on Bitcoin returns.

Design/methodology/approach
The authors use advanced time-series econometrics, namely, multivariate generalized autoregressive conditional heteroscedastic-dynamic conditional correlation and continuous wavelet transformation, for the analysis of the daily returns for the aforementioned assets between 01 August 2011 and 01 September 2019.

Findings
First, the authors found a strong evidence of Bitcoin’s mean reverting trend in the long run while its volatility has decreased significantly since 2013. After separating the EPU into two regimes (high and low), diversification opportunities with Bitcoin seems to disappear in a high EPU period, while the hedging opportunity tends to prevail in a low EPU period for all classes of assets. Importantly, the findings indicate that Bitcoin offers short-term diversification for sustainable and Islamic equity as well as energy stocks during a low uncertainty period. Consequently, in relation to the policy uncertainty, Bitcoin provides similar hedging opportunities than commodities like Gold and Silver. Overall, the study shows that EPU is remarkably important in explaining the average portfolio returns of Bitcoin, suggesting that this indicator can be perceived as a decent explanatory factor for portfolio diversification.

Originality/value
The study significantly extends the empirical literature of Bitcoin’s portfolio diversification by taking EPU into consideration. To the best of authors’ knowledge, this is one of the few studies to investigate the asymmetric effects of US EPU on Bitcoin’s hedging capabilities by taking into account major conventional equity, sustainable equity, Islamic equity, gold, silver and oil.
Inquiry into faith-based social reintegration programs for recovering drug addicts in Nigeria
Authors: Olajire Oluyinka Olutola , Oyekola Isaac Akintoyese 
Published: May 2022

Purpose
The purpose of this study is to subject faith-based organizations (FBOs)-operated social reintegration programs for recovering drug addicts to scrutiny to understand their effectiveness in addressing the three-pillar social needs.

Design/methodology/approach
Using concurrent mixed methods research design, a sample size of 156 respondents, 15 in-depth interviewees and 12 key informants was selected purposely from three FBOs and three National Drug Law Enforcement Agency (NDLEA) State Command Areas in Nigeria. Data were collected using questionnaire survey, interviews, observation and document review, and then analyzed using descriptive and content analyses.

Findings
Findings showed nine different noncore social reintegration programs for recovering drug-addicts with different required rates of participation and diverse purposes. Also, the results showed that the three-pillar social needs of recovering drug addicts for successful reintegration into the society were not provided for by the FBOs. Finally, findings showed that majority of the respondents were only slightly satisfied with the overall services rendered at the selected FBOs, and these services were not properly monitored by relevant government agency.

Social implications
Appropriate regulations that will check and balance the activities of treatment providers involved in social reintegration is recommended to achieve optimal level of physical, psychological and social health for recovering drug addicts.

Originality/value
To the best of the authors’ knowledge ,this is a pioneer study that investigated faith-based social reintegration programs for recovering drug addicts in Nigeria.
Patient perceptions of psoriatic disease in Japan: Results from the Japanese subgroup of the Understanding Psoriatic Disease Leveraging Insights for Treatment (UPLIFT) survey
Authors: Torii Hideshi , Kishimoto Mitsumasa , Tanaka Masayuki , Noguchi Hidehisa , Chaudhari Siddharth 
Published: May 2022

AbstractThe population‐based Understanding Psoriatic Disease Leveraging Insights for Treatment (UPLIFT) survey was designed to better understand patient and dermatologist perceptions of the disease burden of psoriasis (PsO) and their treatment expectations. UPLIFT was a cross‐sectional, quantitative, online survey conducted in Europe, North America, and Japan between 2 March and 3 June 2020. In Japan, 391 patients reporting a diagnosis of PsO and/or psoriatic arthritis (PsA) were surveyed (75% had PsO alone, 23% had PsO and PsA, and 2% had PsA alone). Self‐reported body surface area (BSA) data were available for 309 Japanese patients, with the majority (80%) reporting PsO‐involved BSA ≤3 palms. Current symptoms of PsO were rated as moderate or severe by 43% of Japanese patients with BSA ≤3 palms, and severe by 44% of patients with BSA 4–10 palms. PsO frequently occurred in ≥1 special areas, most commonly the scalp in 76% of Japanese patients with BSA ≤3 palms, and ≥90% of those with BSA ≥4 palms. Furthermore, musculoskeletal symptoms in 42% of patients with PsO alone were suggestive of PsA. Whereas Japanese patients with BSA ≤3 palms mainly reported receiving topical therapy alone (34%) or no treatment (32%), 64% patients with BSA 4–10 palms reported receiving systemic therapy. Overall, 21% of Japanese patients with self‐perceived mild symptoms of PsO and 48% of patients with special area involvement experienced at least a moderate impact of disease on quality of life (Dermatology Life Quality Index score >5). Moreover, patients and dermatologists differed in their perceptions of determinants of PsO severity and treatment, and office visit discussions. In general, these findings from the Japanese subgroup of the UPLIFT survey demonstrated that a high proportion of patients perceived their symptoms to be moderate or severe irrespective of the level of skin involvement, suggesting a persistent unmet treatment need.
Therapeutic outcomes and prognostic factors in patients with hypertrophic herpes simplex infection treated with imiquimod: A systematic review and meta‐analysis of individual patient data from case reports and case series
Authors: Leeyaphan Charussri , Nanchaipruek Yanisorn , Phinyo Phichayut 
Published: May 2022

AbstractHypertrophic herpes simplex (HHS) often has atypical presentations, such as a hypertrophic mass or ulcers, with chronic courses. This situation poses a diagnostic challenge and results in delayed treatment. Imiquimod was used as a treatment for HHS by several studies, but the therapeutic outcomes varied. This systematic review and meta‐analysis of individual patient data was conducted to investigate the therapeutic outcomes and prognostic factors of imiquimod treatment for patients with HHS. Biomedical databases (Embase, PubMed, Medline, Cochrane Controlled Trials Register, and ClinicalTrials.gov) were searched for all types of clinical studies reporting the complete cure rate and the time to complete response to imiquimod therapy between 1926 and 2021. Quantitative analysis of individual patient data was performed using multivariable flexible parametric survival regression with cluster variance correction. A total of 12 019 articles were identified and screened for eligibility. Twenty‐five studies (21 case reports and four case series) with a combined total of 42 patients were included. The complete cure rate for imiquimod treatment was estimated at 88.1%. The median time to complete response was 60 days (95% confidence interval 35–70). Combined treatment, male sex, and an age less than 50 years were identified as significant prognostic factors for a shorter time to complete cure. A severe local reaction was reported in 2.3%. Imiquimod therapy has high effectiveness and safety in curing HHS. Patients who were male or younger than 50 years or whose treatments were combined with thymidine kinase‐dependent antivirals had the best prognoses and were more likely to respond to treatment.
Graminoids vary in functional traits, carbon dioxide and methane fluxes in a restored peatland: Implications for modelling carbon storage
Authors: Goud Ellie M. , Touchette Sabrina , Strachan Ian B. , Strack Maria 
Published: May 2022

Abstract

One metric of peatland restoration success is the re‐establishment of a carbon sink, yet considerable uncertainty remains around the time‐scale of carbon sink trajectories. Conditions post‐restoration may promote the establishment of vascular plants such as graminoids, often at greater density than would be found in undisturbed peatlands, with consequences for carbon storage. Although graminoid species are often considered as a single plant functional type (PFT) in land‐atmosphere models, our understanding of functional variation among graminoid species is limited, particularly in a restoration context.

We used a traits‐based approach to evaluate graminoid functional variation and to assess whether different graminoid species should be considered a single PFT or multiple types. We tested hypotheses that greenhouse gas fluxes (CO2, CH4) would vary due to differences in plant traits among five graminoid species in a restored peatland in central Alberta, Canada. We further hypothesized that species would form two functionally distinct groupings based on taxonomy (grass, sedge).

Differences in gas fluxes among species primarily reflected variation in leaf physiology related to photosynthetic efficiency and resource‐use, and secondarily by plant size. Multivariate analyses did not reveal distinct functional groupings based on taxonomy or environmental preferences. Rather, we identified functional groups defined by plant traits and carbon fluxes that are consistent with ecological strategies related to differences in growth rate, resource‐acquisition and leaf economics, representing plants with either a strategy to grow quickly and invest in resource capture or to prioritize structural investment and resource conservation. These functional groups displayed larger average carbon fluxes compared to graminoid PFTs currently used in modelling.

Synthesis. Existing PFT designations in peatland models may be more appropriate for pristine or high‐latitude systems than those under restoration. Although replacing PFTs with plant traits remains a challenge in peatlands, traits related to leaf physiology and growth rate strategies offer a promising avenue for future applications.
Predictors of progression in rheumatoid arthritis‐associated interstitial lung disease: A single‐center retrospective study from China
Authors: Liu Lei , Fang Chunxiao , Sun Bo , Bao Ruyi , Zhang Hongfeng 
Published: May 2022

AbstractAimInterstitial lung disease (ILD) is a common extra‐articular manifestation of rheumatoid arthritis (RA) and is associated with high mortality, especially in progressive ILD. We aimed to identify predictors of disease progression in the early stages of ILD in a large sample of patients with RA.MethodThe medical records of 201 RA‐ILD patients were retrospectively analyzed. According to changes in their pulmonary function tests, patients were divided into progressive disease and stable disease groups. Data were collected on clinical characteristics, laboratory findings, chest high‐resolution computed tomography, and therapeutic agents. Univariate and multivariate analyses were performed to identify predictors of ILD progression.ResultsDuring a median follow up of 38 months, 105 (52.5%) patients were diagnosed with progressive ILD. These patients were mostly male, past or present smokers (P = 0.028, P = 0.021, respectively). Higher Health Assessment Questionnaire‐Disability Index score and higher Disease Activity Score in 28 joints with erythrocyte sedimentation rate (DAS28‐ESR) were observed in the ILD progression group (P = 0.003, P < 0.001, respectively). There were no significant differences in baseline respiratory symptoms, pulmonary function, or laboratory features. Multivariate analysis indicated that high DAS28‐ESR, definite usual interstitial pneumonia pattern, fibrosis score, and less use of cyclophosphamide were independent risk factors for RA‐ILD progression. Fifteen (7.46%) patients died during the follow up, and the most frequent cause of death was lung infection.ConclusionOur results suggested that high disease activity, definite usual interstitial pneumonia pattern, fibrosis score, and less use of cyclophosphamide at the onset of ILD may indicate the progression of ILD in RA patients.
Epidermal growth factor receptor tyrosine kinase inhibitors for de novo T790M mutation: A retrospective study of 44 patients
Authors: Chang John Wen‐Cheng , Huang Chen‐Yang , Fang Yueh‐Fu , Chang Ching‐Fu , Yang Cheng‐Ta , Kuo Chih‐Hsi Scott , Hsu Ping‐Chih , Wu Chiao‐En 
Published: May 2022

AbstractBackgroundThis study aimed to evaluate possible treatment strategies for patients with de novo T790M mutation‐positive (T790M+) non‐small‐cell lung cancer (NSCLC).MethodsPatients diagnosed with de novo T790M+ NSCLC and treated with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR‐TKIs) between 2011 and 2018 at a regional hospital in Taiwan were retrospectively reviewed. Their clinicopathological characteristics and subsequent treatment information were collected, and potential prognostic factors were identified using univariate and multivariate analyses.ResultsAll tumors with T790M mutations coexisted with sensitizing mutations. Through the last follow‐up in May 2021, afatinib and osimertinib demonstrated better progression‐free survival (PFS, p < 0.01) and overall survival (OS, p < 0.01) than gefitinib and erlotinib. Additionally, patients with low T790M ratios had better PFS than those with high T790M ratios, implying that the proportion of T790M+ tumors determined the response to EGFR‐TKIs. Multivariate analysis confirmed that both EGFR‐TKI treatment (osimertinib hazard ratio [HR] 0.06, 95% confidence interval [CI] 0.01–0.30; afatinib HR 0.09, 95% CI 0.02–0.39) and a low T790M ratio (HR 0.29, 95% CI 0.12–0.69) were independently favorable prognostic factors for patients with de novo T790M+ NSCLC. Median PFS was 6.1 (95% CI 4.4–7.8) months. In addition, patients treated with first‐generation (1G)/second‐generation (2G) EGFR‐TKIs followed by osimertinib (n = 8) demonstrated the best OS compared with patients treated with frontline osimertinib (n = 5) or 1G/2G EGFR‐TKIs without osimertinib (n = 28, p < 0.01).ConclusionSequential TKIs may represent an alternative option for de novo T790M mutation, particularly frontline afatinib and tumors with low T790M ratios.