bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of quality and effectiveness of rendering medical care to patients with gonococcal infection in medical institutions
Authors: Rumyantseva M. A. , Isaeva N. V. 
Published: March 2022

Objective. To assess the intensity of epidemic process in a long-term dynamics of gonorrhea sickness rate and evaluate the quality and effectiveness of rendering medical care to patients with this infection in medical institutions of Perm.
Materials and methods. In this work, the data of official statistics of the State Budgetary Institution of Public Healthcare Perm Regional Clinical Dermatovenerological Dispensary are presented: official statistical form 12 Information on the number of diseases as well as accounting forms accepted by the Ministry of Public Health of Perm Krai. Epidemiological, descriptive-evaluative and analytical studies of the type case-control, sociological (questioning method) and statistical methods were used.
Results. A long-term dynamics of gonococcal infection morbidity among the population of Perm for 19902020 was characterized by a marked tendency to decrease, an average annual decrease rate was 7.5 %. Despite the tendency to decline, from 2018 to 2020, there was observed an activation of epidemic process of the gonococcal infection. The growth rate was 137.5 %. Based on special investigations, it was established that 55.4 % of patients addressed to private clinics, 44.6 % (p0.05) to state ones (SBIPH PK RCDVD). In general, 76.5 % of patients from state and private clinics remained uncontrolled from the side of medical services. Thus, in three thirds of the foci, an active search of the sources of the infectious agent was not carried out. While studying medical documentation of 666 foci, epidemic diagnostics was performed only in 166 (24.9 %), in 500 foci the infectious agent source was not detected and investigated. At the same time, out of 500 foci, in 340 (68.0 %) one sexual partner for each focus remained unexamined, in 125 (25.0 %) foci two-three sexual partners, and in 35 (7.0 %) foci more than three sexual partners.
Conclusions. Recent years have witnessed the activation of epidemiological process of gonococcal infection in Perm. The gonococcal infection morbidity 2.5 times exceeded the indicators in the country as a whole. Patients with gonococcal infection addressed to state and private clinics in 55.4 % and 44.6 % of cases, respectively. Three thirds of patients with gonorrhea receive medical care not in a full volume, and with bad quality. In the state institutions, such patients make 15 %, in private ones 85 %.
Body dysmorphic disorder: some diagnostic approaches
Authors: Khramtsova N. I. , Plaksin S. A. , Zayakin Yu. Yu. , Glushenkov A. S. , Fadeeva M. V. , Sotskov A. Yu. , Ponomarev D. N. 
Published: March 2022

Objective. Dysmorphophobis (body dysmorphic disorder, BDD) is a mental disorder characterized by excessive preoccupation with any imaginary or mild physical defect that causes significant discomfort, distress in the social sphere and other important areas of human activity.
The aim was to analyze the possibilities of foreign validated methods for detecting body dysmorphic disorder in a Russian-speaking audience.
Materials and methods. Two questionnaires have been translated into Russian, BDDQ-DV and DCQ. The survey was carried out in three samples: patients of a somatic hospital (55 women), clients of a plastic surgeon (71 women) and senior students of the Perm State Medical University (31 women).
Results. A positive answer to the question about the presence of a defect in appearance was given by the majority of the survey participants. Most of them described in detail those defects of their appearance that bother them. More than half of them think a lot about the defects. A question with a request to describe the "defect" allows the doctor to clarify the indications for its correction. If the medical correction is not indicated, the physician of the somatic profile can refer the patient for psychological correction. Answers regarding the severity of feelings about the defect, about disorders in social and professional life, about how long it takes to think about a defect and attempts to hide it, as well as whether the respondents have previously consulted about it with a doctor, and what were the results of consultation, allow us to suspect the presence of BDD and refer the respondent to a profile specialist. The analysis of internal consistency demonstrated the possibility of using these questionnaires in scientific research (Cronbach's alpha 0.820.84).
Conclusions The presented Russian-language versions of the DCQ and BDDQ-DV questionnaires can be recommended for scientific research as a screening tool for detecting body dysmorphic disorder among females of different age groups. However, their implementation in practice requires a deeper adaptation to the Russian-speaking audience.
Vivienda popular, arquitectura, investigación e innovación
Authors: Durante Maria 
Published: March 2022

El caso del Instituto de Investigaciones y Proyectos (IIP) y el Centro de Investigaciones de la Vivienda Popular de la Universidad de Buenos Aires (CIVPUBA), que funcionaron durante 1973 y 1974, permite ver una experiencia de institución científico-tecnológica que aborda el problema del hábitat popular de una manera compleja, interdisciplinaria e innovadora. Dos espacios hermanados, en el seno de la facultad de arquitectura de la UBA, donde el espacio de investigación se articuló con la política pública, diversos organismos de la sociedad civil y el sector privado. Una propuesta que buscó ir en sintonía con el proyecto político del tercer peronismo, pero que, a la vez, sintetizó un proceso de discusiones y prácticas desarrolladas por una generación de arquitectos que se forjó en la resistencia y en lugares generalmente marginales desde 1955. Esta experiencia permite ver los frutos de una generación que avanza en sus reflexiones y construye propuestas concretas; permite ver un proyecto de ciencia y técnica articulado con un proyecto de universidad y un proyecto de sociedad al servicio de las problemáticas de los sectores populares. Experiencias que, a pesar de gestarse en un contexto conflictivo muy distinto, hoy permiten recuperar elementos que sirven para pensar nuevas propuestas de articulación.
Correction to the article “Colorectal Screening Program in Northern Portugal: First Findings”, Published on Acta Med Port 2022 Mar;35(3):164-169.
Authors: Monteiro Hugo , Tavares Fernando , Reis João , Ferreira Gustavo , Campos M. José , Costa Sérgio , Carvalho Laura , Carvalho João , Pedroto Isabel , Soares José , Henrique Rui , Bento Maria José , Hassan Cesare , Dinis-Ribeiro Mário 
Published: March 2022

On page 168, Table 2, where it reads:On page 168, Table 2, where it reads:Advanced phenotype rate* [n (%)] 35 (49.0) 10 (52.0) 25 (47.0) 0.606Carcinoma** [n (%)] 2 (2.0) 1 (5.0) 1 (2.0)It should read:Advanced phenotype rate [n (%)] 179 (22.0) 57 (30.0) 35 (21.0) 29 (21.0) 24 (14.0) 34 (24.0)Carcinoma [n (%)] 3 (0.4) 2 1On page 168, Table 3, where it reads:ADR (%) 80.0 -Advanced adenoma (%) 44.0 15.9It should read:ADR (%) 41.0 -Advanced adenoma (%) 22.0 15.9 Article published with errors: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15904
Um UM OLHAR PARA O ESTADO DE CONSERVAÇÃO DOS SAMBAQUIS URBANOS DE JOINVILLE
Authors: Twardowsky Ana Cristina , Bandeira Dione da Rocha , Pascoal Leite de Camargo Guedes Sandra 
Published: March 2022

Os sambaquis são morros artificiais cobertos por vegetação e foram construídos por povos pré –coloniais que habitaram o Brasil fazendo parte do patrimônio cultural arqueológico brasileiro. O presente estudo revisou o estado de conservação dos sítios arqueológicos do tipo sambaqui, existentes na área urbana de Joinville. Os critérios utilizados para reavaliar o estado de conservação dos sítios foram abrasão; erosão acelerada antropogênica; impacto humano direto, edificações, deposição de resíduos sólidos, destruição mecânica; os mesmos utilizados por Oliveira (2000). Foi constatado que a realidade dos sítios da área urbana não sofreu mudanças significativas em relação a destruição antropogênica, mecânica e deposição de lixo.
The Impact of Social Determinants of Health on 30 and 90-Day Readmission Rates After Spine Surgery
Authors: Mohanty Sarthak , Lad Meeki K. , Casper David , Sheth Neil P. , Saifi Comron 
Published: March 2022

Background:
Since its 2012 inception, the U.S. Centers for Medicare & Medicaid Services Hospital Readmissions Reduction Program (HRRP) has espoused cost-effective health-care delivery by financially penalizing hospitals with excessive 30-day readmission rates. In this study, we hypothesized that socioeconomic factors impact readmission rates of patients undergoing spine surgery.

Methods:
In this study, 2,830 patients who underwent a spine surgical procedure between 2012 and 2018 were identified retrospectively from our institutional database, with readmission (postoperative day [POD] 0 to 30 and POD 31 to 90) as the outcome of interest. Patients were linked to U.S. Census Tracts and ZIP codes using the Geographic Information Systems (ArcGIS) mapping program. Social determinants of health (SDOH) were obtained from publicly available databases. Patient income was estimated at the Public Use Microdata Area level based on U.S. Census Bureau American Community Survey data. Univariate and multivariable stepwise regression analyses were conducted. Significance was defined as p < 0.05, with Bonferroni corrections as appropriate.

Results:
Race had a significant effect on readmission only among patients whose estimated incomes were <$31,650 (χ2 = 13.4, p < 0.001). Based on a multivariable stepwise regression, patients with estimated incomes of <$31,000 experienced greater odds of readmission by POD 30 compared with patients with incomes of >$62,000; the odds ratio (OR) was 11.06 (95% confidence interval [CI], 6.35 to 15.57). There were higher odds of 30-day readmission for patients living in neighborhoods with higher diabetes prevalence (OR, 3.02 [95% CI, 1.60 to 5.49]) and patients living in neighborhoods with limited access to primary care providers (OR, 1.39 [95% CI, 1.10 to 1.70]). Lastly, each decile increase in the Area Deprivation Index of a patient’s Census Tract was associated with higher odds of 30-day readmission (OR, 1.40 [95% CI, 1.30 to 1.51]).

Conclusions:
Socioeconomically disadvantaged patients and patients from areas of high social deprivation have a higher risk of readmission following a spine surgical procedure.

Level of Evidence:
Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Experimental Study on the Performance of Electrical Submersible Pump Operating with Ultraviscous Oil
Authors: Porcel Cristhian , Biazussi Jorge Luiz , Monte Verde William , Estevam Valdir , Bannwart Antonio Carlos , Tavares Alexandre , Santos Marcelo Paulino de Lima , Rocha Paulo Sérgio de M. V. 
Published: March 2022

Summary
The production of high-viscosity crude oil can be challenging owing to portfolio limitations and lack of energy efficiency in artificial lift systems, especially for ultraheavy oil in deepwater fields. In recent decades, the electrical submersible pump (ESP) has improved significantly, and this technology is commonly applied in this context. However, few studies in the literature discuss the behavior of these pumps with nonconventional oils such as ultraviscous ones. This work investigates the performance of a 10-stage ESP, when it operates with a single-phase flow of ultraviscous oil. For this purpose, an experimental circuit was set up; the pump was submitted to tests in which the viscosity of the fluid varied from 8 to 4,170 cp and rotational speed between 1,200 and 3,500 rev/min. A subsequent analysis compared the pump’s experimental viscous performance and the theoretical performance calculated by the methods available in the literature. This analysis highlighted the lack of precision of the existing correction performance models, and new empirical correlations are proposed to correct the ESP performance with viscous fluid. There were doubts at first as to the possibility of ultraviscous block, but the ESP model tested handled fluid with a viscosity up to 4,170 cp. Finally, the performance parameters of the ESP were calculated using a phenomenological 1D model based on the loss analysis developed by the authors, which revealed good results and a powerful tool to adjust the size of the ESP for definitive production system.
Trends in Treatment of Ankyloglossia: A Survey Based, Provider Perspective on Current Practice Trends
Authors: Goosmann Madeline , Aviles Claudia I. Cabrera , Shah Jay 
Published: March 2022

Abstract
Background
Ankyloglossia, “tongue tie,” is a condition in which the lingual frenulum is shortened. Ankyloglossia can interfere with speech articulation as well as tasks like chewing or playing an instrument; however, the biggest factor is difficulty breastfeeding. To treat ankyloglossia, providers perform frenectomy or frenotomy. With minor bleeding and recurrence as the common complications, frenotomies are generally well received by providers and parents. This survey polled provider preferences and views on the ankyloglossia treatments.
Methods
Proceeding IRB approval. A 22-question survey on treatment and trends for ankyloglossia was sent to SENTAC (Society for Ear Nose Throat Advancement in Children) members. Questions addressed area of sub-specialization, years in practice, type of practice, performance of frenotomy and frenectomy, criteria for surgical repair, procedure frequency and change over time, and individual comments.
Results
Of the 62 respondents, there was a difference between use of frenotomy vs frenectomy (94.3% vs 38.6%) p<0.001. Common provider criteria for the procedure were improvement of pain with breastfeeding and improvement latching, followed by future speech concerns. Of respondents, 94% reported that they would repair anterior ties; 63% of respondents perceived an increase of frenotomies in the past five years both in their practice and in the practice of colleagues. Respondents also reported an increase in parents asking about tongue ties.
Conclusion
Treatment of this condition tends to be very provider dependent/regional. The results from this survey in association with the new consensus statement will lead towards the creation of a clinical care pathway that would stabilize these numbers and create a stream-lined process.
Effectiveness of The Fixtoe Device® In Plantar Pressure Reduction: A Preliminary Study.
Authors: Ruiz-Ramos Maria , Orejana-García Ángel Manuel , Vives-Merino Ignacio , Bravo-Llatas Carmen , Lázaro-Martínez José Luis , Molines-Barroso Raúl Juan 
Published: March 2022

Abstract
Background: Metatarsalgia is a common foot condition. The metatarsophalangeal stabilizing taping technique described by Yu et al. has shown good clinical results as a provisional treatment in propulsive metatarsalgia. 35 The Fixtoe Device®, a novel orthopedic device, intends to simulate stabilizing tape. However, to date, there is no evidence of its effectiveness.Methods: The aim of this study was to assess plantar pressure changes using the Fixtoe Device®, in comparison with the traditional method (stabilizing tape) in a young, healthy sample thorough a cross-sectional study. Maximal pressure (Kpa) and pressure-time integral (Kpa/s) in the second metatarsal head were measured in twenty-four healthy volunteers. Registers were taken in four different conditions: barefoot, traditional stabilizing tape, Fixtoe Device® without metatarsal pad, and Fixtoe Device® with metatarsal pad. Results: Mean second metatarsal head maximal pressure and mean pressure-time integral showed statistical difference among the four analyzed conditions (p < 0.0001 in both cases). The improvement in maximal pressure and pressure-time integral obtained in each intervention also showed significance (p < 0.0001 in both cases). Comparing the improvement of the Fixtoe Device® with and without metatarsal pad with that of tape condition showed a moderate to high and moderate effect size for both peak pressure and pressure-time integral reduction.Conclusions: The Fixtoe Device® reduces median maximal pressure and median pressure-time integral under the second metatarsal head in healthy young individuals. The Fixtoe Device® shows higher effectiveness than the traditional second metatarsophalangeal joint stabilizing taping technique. To our knowledge, this is the first investigation proving the effectiveness of the recently developed Fixtoe Device® in terms of plantar pressure modification, which leads the way to its use in clinics.
Papaver decaisnei: GC-MS alkaloids profiling, in vitro antioxidant, and anticancer activity
Authors: Aj.abduljabbar Ahmed , O.Abdullah Fuad , K.Abdulrahman Kamaran , Galali Yaseen , Sh.Sardar Abdullah 
Published: March 2022

Abstract
The Papaver L. plant have been well known as a source of pharmaceutically valuable alkaloids (noscapine, thebaine, codeine, roemerine, papaverine and morphine). The current study investigates the phytochemical, in-vitro antioxidant, and anticancer activities of papaver decaisnei, an endemic plant species to the flora of Kurdistan-Iraq. The chemical analysis of the methanolic (MeOH) extracts of flowers, leaves, and roots of papaver decaisnei were made by using gas chromatography-mass spectrophotometry (GC-MS), and the antioxidant activity evaluation done by radical scavenging [on 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2j-azino-bis (3- ethylbenzothiazoline-6-sulfonic acid) (ABTS)], and reducing power [cupric reducing antioxidant capacity (CUPRAC), and ferric reducing antioxidant power (FRAP)] assays. The anticancer actions were presented as IC50 (inhibitory concentration at 50%) on human colorectal adenocarcinoma (Caco-2), mammary cancer cells (MCF-7), and human cervical carcinoma (HeLa) cells. The results of the phytochemical analysis showed 17, 19, and 22 chemical compounds for flowers, leaves, and roots of P. decaisnei, respectively. The prevalent organic compounds of P. decaisnei were alkaloids, phenolics, fatty acids, esters, and phytosterols, namely Roemerine (70.44%), Decarbomethoxytabersonine, 9,12,15-Octadecatrien-1-ol, Hexadecanoic acid, 6,8-Dioxa-3-thiabicyclo(3,2,1)octane 3,3-dioxide, and γ-Sitosterol. The antioxidant activity of plant organ extracts was within 39.1-143.5 μg/ml for DPPH and 123.12-276.4 μg/ml for ABTS assays, while, the FRAP and CUPRAC values ranged within 12.4- 34.3 and 42.6-75.8 μg/ml, respectively. The anticancer action of P.decaisnei organ extracts was found against all tested human cell lines (Caco-2, MCF-7, HeLa) with inhibitory concentrations (IC50) values between 125.3-388.4 μg/ml. The presented data on alkaloid contents and biological activity of P. decaisnei can serve a ground knowledge for the future biomedical synthesis and cancer research projects.
Adherence, physical limitation and social participation in leprosy patients in a high-complexity hospital
Authors: Cavalheiro Amanda Henriques , Frade Marco Andrey Cipriano , Ungari Andrea Queiroz 
Published: March 2022

Abstract
Background: Therapies and procedures to improve the quality of life of patients and adherence to treatment is a concern for the health systems and for health professionals. More studies related to preventive and therapeutic education, using educational technologies for health purposes are needed. Objectives: To demonstrate the educational instruments developed by the researcher, as animated videos and posts, as well as the pharmacotherapeutic monitoring of pharmaceutical care, increase the adherence to the treatment of patients diagnosed with leprosy in a high-complexity hospital. Methods: This is a longitudinal study, using quantitative and qualitative assessment tests to assess adherence to treatment and general knowledge about the disease and quality of life. From the data, educational materials were produced and tested on patients. Then, the impact of follow-up and instructional materials on treatment adherence was evaluated. Results: Treatment adherence increases after the intervention of pharmaceutical care and health education, as per the Morisky-Green treatment test. The methodology was more effective in male patients with low education than in women, who already had high adherence. In addition, it was possible to identify that the Morisky-Green and Haynes-Sackett adhesion tests, used in the work, completely differed in their results, they occur to reflect the use of such tools in research in the area. Conclusion: It is possible to increase patient treatment adherence through health education programs and pharmaceutical care.
Osteopontin expression in the invasive front stroma of colorectal adenocarcinoma is associated with tumor budding and prognosis
Authors: Uehara Takeshi , Nakajima Tomoyuki , Iwaya Mai , Matsuda Kazuyuki , Wada Megumi , Nagaya Tadanobu , Miyagawa Yusuke , Ohta Hiroyoshi 
Published: March 2022

Abstract
Background: Tumor budding (TB) is an important prognostic factor in colorectal carcinoma (CRC). Osteopontin (OPN) functions in various processes such as immune response, migration and invasion, angiogenesis, epithelial–mesenchymal transition (EMT) and metastasis. However, the involvement of OPN and CD44v6, which is a receptor for OPN, in TB has not been clarified. Therefore, we examined the relationship of OPN with TB in CRC and compared the clinicopathological features. Methods: We investigated the expression of OPN and CD44v6 in 83 cases of CRC by immunostaining and analyzed the clinicopathological features.Results: OPN expression was observed only in the cytoplasm of stromal cells such as macrophages and fibroblasts, and not cancer cells. There was a significant correlation between OPN positivity and the degree of differentiation at the invasive front and TB grade. CD44v6 was positive in cancer cells in 72 cases (86.7%) and negative in 11 cases (13.3%). A statistically significant effect on overall survival (OS) was identified between the OPN-positive group [median OS: 1586 (range, 30–2749) days] and the OPN-negative group [median OS: 1901 (range, 8–2665) days] (log-rank test, p=0.011).Conclusions: OPN analysis may reveal factors that influence prognosis.