bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alergia a penicilina
Authors: Ortega-Cisneros Margarita , Moras-Villela Victoria Leilani , Delgado-Bañuelos Angélica , Madrigal-Beas Ileana María , Aguilar-Chávez Yoal , Ochoa-García Itzel Vianey , Chávez-Meléndez Miguel Ángel , Gómez-Hernández Noemí 
Published: January 2022

Los betalactámicos son los antimicrobianos más utilizados por su seguridad y eficacia. En este grupo se incluyen las penicilinas, las cefalosporinas, los carbapenémicos y los monobactámicos. La penicilina constituye la primera causa de alergia a medicamentos: 10 a 20 % de la población se etiqueta como alérgica a la misma, en muchas ocasiones erróneamente. Se ha reportado reacción cruzada entre penicilinas y cefalosporina en 2 a 5 %. No hay reacción cruzada entre penicilinas y aztreonam, pero sí con ceftazidima. En la fisiopatología de las reacciones de hipersensibilidad a penicilina se incluyen todos los mecanismos de la clasificación de Gell y Coombs. La estratificación de acuerdo con el riesgo permite tomar la decisión más objetiva para etiquetar al paciente como alérgico. En la evolución natural de la alergia a la penicilina, 80 a 90 % de los pacientes pierde dicha sensibilidad a los 10 años. De ser indispensable, el paciente puede ser sometido a un protocolo de desensibilización. El médico inmunoalergologo es una pieza clave en la selección del paciente, la elaboración de los protocolos de reto y la desensibilización en un ambiente controlado.
How Did Students Perceive Classroom Learning under Strict COVID-19 Pandemic Closures and Restrictions?
Authors: Sako Takayoshi 
Published: January 2022

The COVID-19 pandemic of 2020 required strict infection prevention measures worldwide, including school closure. After school reopened, we implemented Japan’s strict COVID measures, under which close contact in pairs or groups, as well as vocalizing in unison, was proscribed, with students having to remain quiet and face the blackboard.
This study’s aim is to answer the question of how students felt about learning under such extreme constraints. One of the most noticeable findings from the responses to the survey of the 2020 class was that they felt the lack of collaborative learning experiences; hence, in 2021, we implemented changes that would allow for more collaboration while still adhering to COVID prevention guidelines. Among the various collaborative learning activities in the classroom, students reported that they found value in debate activities that challenged their English language skills and critical thinking. Overall, however, students found comfort and value in a semblance of learning with their peers.
It was concluded that even in a volatile and uncertain situation, such as a pandemic, it is crucial to improve environments for collaborative learning. In the future, quantitative study of the impact of collaborative learning on students’ English proficiency will be a useful follow-up study.
Analisis Budaya Organisasi, Kompensasi, Dan Disiplin Kerja Terhadap Organizational Citizenship Behavior (OCB) Melalui Motivasi Sebagai Variabel Moderasi
Authors: Suseno  , Kirana Kusuma Chandra , Lukitaningsih Ambar 
Published: January 2022

This research purported to discover the influence of corporate culture, compensation and working discipline on Organizational Citizenship Behavior (OCN) using motivation as moderating variable. Research population covered all employees in PERUMDAM Bantul having permanent officer status as many 115 persons. Research sampling was based on Slovin method resulting in 90 people selected using random sampling technique. Research method was based on quantitative approach. The research utilized SmartPLS 3.2.8 to conduct inferential analysis. Based on the result of inferential analysis using SmartPLS 3.2.8 it can be concluded that there was tangible influence of corporate culture, compensation and working discipline on Organizational Citizenship Behavior (OCN) using motivation as moderating variable.The result of this research is applicable as reference to improve OCB in any companies simply by strengthening corporate culture, rationalizing compensation, maintaining workplace discipline and motivating the employees to work even harder.
Keputusan Pembelian Ditinjau dari Promosi Menggunakan Media Sosial dan Word of Mouth Marketing
Authors: Mahardhika Mustafidah , Arintowati Dyan 
Published: January 2022

The purpose of this research is to determine the effect of promotion using social media and word of mouth marketing on purchasing decisions for beauty clinic services. This research is belonging to quantitative research with data collection techniques using interviews, documentation, and questionnaires. For data analysis using multiple linear regression analysis.
The results showed that at this time, promotions using social media and word of mouth marketing influence purchasing decisions still, either partially or simultaneously. From these results, social media is still effectively used as a tool on promoting products. Word of mouth marketing also has an effective influence in affecting purchasing decisions. Where consumers still trust the recommendations of their close environment on products buying decision.

Kata Kunci: social media, word of mouth marketing, buying decision
The Effect of Aromatherapy and Abdominal Massage Applied to Infants on Constipation and Maternal Anxiety Level
Authors: METİN KARAASLAN Mehtap , ARIKAN Duygu 
Published: January 2022

Backround: As constipation is a chronic and common disease, cost-effective therapies are needed. In addition, there is a limited number of studies on the aromatherapy massage and normal abdominal massage, which are the traditional and complementary applications included in the constipation management program in the literature.However, there is no study about each of these two applications being superior to the other.
Method: The research was conducted as a quasi-experimental study between June 2018 and February 2020. The sample of the study was composed of a total of 69 infants and their parents including 23 in aromatherapy massage group, 23 in traditional massage group, and 23 in control group, who met the inclusion criteria. The data were assessed by using the personal information form, the intestinal functions assessment form, State Anxiety Inventory, and abdominal massage checklist. The data were assessed by Shapiro Wilk test, one-way analysis of variance, Kruskal Wallis test, chi-square test, and generalized linear model. The significance level was taken as p
Mental Health and Quality of Life among Women with Incontinence
Authors: KIZILKAYA BEJİ Nezihe , MURAT Merve , ÇAYIR Gülsen 
Published: January 2022

Incontinence is an individual's involuntary incontinence of urine and/or feces. It is a serious health problem that significantly affects the individual's mental health and quality of life. Women experience incontinence 3-4 times higher than men, and the prevalence of incontinence continuously increases with age in both sexes.
The diagnosis, treatment, and rehabilitation process affect an individual psychologically, physically, socially, and emotionally. Women who suffer from incontinence restrict daily life, such as not exercising, traveling, and having social and emotional interactions. Over time women socially isolated and may lose their self-confidence. It decreases the quality of life with feelings of shame, depression, anxiety, and discomfort. This process affects women's mental health.
The review aims to examine the effects of incontinence on women's mental health and quality of life in line with current researches and suggestions that women's health and psychiatric nurses implement in the clinic areas.
Smoking Status and Health Beliefs Related to Smoking of Nurses in Working a Cancer Hospital, in Turkey
Authors: KAMIŞLI Songül , GÜNER Pınar , HAYRAN Kadir Mutlu 
Published: January 2022

Purpose: Few studies are available that evaluate oncology nurses’ health beliefs related to smoking and smoking status. The purpose of this study was to evaluate the health beliefs regarding smoking among nurses and status working in a cancer hospital.
Methods: This descriptive study was conducted among 152 nurses in a cancer hospital in Turkey. Data were collected by using The Self-Report Questionnaire Regarding Health Beliefs and Smoking Cessation Self-Efficacy Questionnaire
Results: Median age, body mass index, and working duration with cancer patients of the oncology nurses are 34.0, 23.9, and 9.0, respectively. Of the nurses, 54.1% stated that they have never smoked, while 27% smoke every day. Among regular smokers, 32.1% are in precontemplation stage. Of the participants, 91.9% noted that ‘smokers are more likely to have cancer, 45.9% that ‘it is difficult for smokers to quit smoking, and 52.3% that ‘tobacco bans are effective on quitting smoking.
Conclusion: The majority of oncology nurses think that a healthy lifestyle is very important but a few of them follow the advice. Also even though the nurses mostly have healthy living beliefs they can’t reflect these on their behaviors. Nurses working with cancer patients must also be considered as risk groups when planning cancer prevention and tobacco control studies. It is important that nurses should be informed and supported to take part in smoking cessation interventions.
Validity and reliability of the Turkish version of Health Protective Behavior Scale
Authors: ÖDEK Ömer , SAVAŞ Mümin , ZİNCİR Handan 
Published: January 2022

Purpose: The aim of this study is to perform the Turkish adaptation study of the Health Protective Behavior Scale.
Methods: This was a methodological study that was conducted between August 2020 and September 2020. The sample of the study consists of 384 individuals aged 18-59 living in the city center of Kayseri. In this study, "Descriptive Information Form" and "Health Protective Behavior Scale (HPBS)" were used as data collection tools. The reliability of the scale was evaluated by internal consistency, Pearson correlation, and test-retest reliability. The construct validity of the scale was tested by exploratory factor analysis and confirmatory factor analysis.
Results: According to the results of the explanatory factor analysis, 40.748% variance was explained in 4 dimensions in the scale. In the confirmatory factor analysis, a four-dimensional structure was found to fit well (X2/df=2.213 RMSEA=0.056). As a result of the reliability analysis of the scale, it was found that the internal consistency coefficient was α = .82 and the test-retest reliability was r = .81.
Conclusion: It has been determined that HPBS is a valid and reliable measurement tool to determine health protective and development behaviors.
ВПЛИВ РОЗМІРУ ПОР ТА МОРФОЛОГІЇ МЕЗОПОРИСТОГО КРЕМНІЮ НА ВИВІЛЬНЕННЯ МЕТОПРОЛОЛУ ТАРТРАТУ
Authors: WANG HONGJUAN , HU WEI , SALIY OLENA 
Published: January 2022

Purpose. Study pore size effect and morphology of mesoporous silica on metoprolol tartrate release.Methodology. A sample of hollow mesoporous silicon dioxide with amino-functional groups containing 12.7 wt. % metoprolol tartrate has been investigated as potential carriers for the controlled release of active substance. Studies of the release profiles of metoprolol tartrate were performed under the following conditions: dissolution medium was buffer solution with a pH of 7.4 (phosphate buffer); sampling time: from 0.5 h before 18 h. The metoprolol concentration in the liquid phase was evaluated by a UV-Vis spectrophotometer (Persee TU-190, Beijing, China) by use of quartz cuvettes with an optical path length of 1 cm at a maximum wavelength of 274 nm.Findings. In this work we have studied mesoporous silica as possible carrier to controlled release of metoprolol tartrate, a drug used in the treatment of some diseases of the cardiovascular system. The material for research was a sample of hollow mesoporous silicon dioxide with amino-functional groups 200–400 nm in size and 20–30 nm in shell thickness. A calibrated curve to determine the amount of metoprolol was constructed by determining the absorption dependence of the concentration of metoprolol in the range from 10 to 300 ppm. The same drug concentration was obtained as calculated from the drug release test formula, which concludes that the release of metoprolol is controlled.Originality. The controlled release of a sample of hollow spheres of mesoporous silicon dioxide filled with metoprolol tartrate was studied, which was synthesized by the School of Chemistry and Chemical Engineering, Qilu University of Technology, using a new technology, where hollow spheres of mesoporous silicon dioxide with amino groups were synthesized using CO2 gas bubbles as templates.Practical value. The metoprolol release amount could achieve a 50% release amounts within 1 hour and 90% within 5 hours, indicating that the synthesized mesoporous hollow sphere could achieve controlled drug release, and shows the potential of carriers with stimulus response and targeted therapy.
ANALISIS SIKAP KONSUMEN DI MASA PANDEMI COVID-19 DAN PENGARUHNYA TERHADAP KEPUTUSAN PEMBELIAN DI COFFEE SHOP JABODETABEK
Authors: Andrianto Mokhamad Syaefudin , Sayekti Andita , Daniel Freddi 
Published: January 2022

abstractThe Covid-19 pandemic has a negative impact on various types of foods and beverages business including a coffee shop. The objective of this research is to analyze consumer attitudes during the Covid-19 pandemic and the influence of consumer attitudes during the Covid-19 pandemic on purchasing decisions at coffee shop. The sample of this research is 100 respondents in Jabodetabek (Jakarta, Bogor, Depok Tangerang, and Bekasi). Sampling methods using purposive sampling technique. Sampling data is collected by distributing questionnaires to consumers who had visited a coffee shop in Jabodetabek. The analysis data using Structural Equation Modeling method with Partial Least Squares. The results of the analysis show that consumers aware with the Covid-19 pandemic and its health protocols. Consumers also apply the government's Covid-19 health protocol. Consumer attitudes during this pandemic have a negative effect on purchasing decisions at coffee shop. abstrakPandemi Covid-19 cenderung berdampak negatif pada berbagai jenis usaha di sektor makanan dan minuman, termasuk coffee shop. Tujuan penelitian ini adalah untuk menganalisis sikap konsumen pada masa pandemi Covid-19 dan pengaruh sikap konsumen pada masa pandemi Covid-19. terhadap keputusan pembelian di coffee shop. Sampel dari penelitian ini adalah konsumen di Jabodetabek sebanyak 100 responden. Pengambilan sampel menggunakan teknik purposive sampling. Pengambilan data dilakukan dengan menyebarkan kuesioner ke konsumen yang pernah melakukan kunjungan coffee shop di Jabodetabek. Analisis data dilakukan menggunakan Structural Equation Modeling (SEM) dengan pendekatan Partial Least Squares. Hasil analisis menunjukkan konsumen mengetahui pandemi Covid-19 dan protokol kesehatan. Konsumen juga menerapkan protokol kesehatan Covid-19 dari pemerintah. Sikap konsumen pada masa pandemi ini berpengaruh negatif terhadap keputusan pembelian di coffee shop.
ANALISIS PENGARUH CUSTOMER EXPERIENCE TERHADAP LOYALITAS PELANGGAN
Authors: Ray Erick Lauren , Wirya Artha I Nyoman , Dewi Erlita Khrisinta 
Published: January 2022

abstractThis study aims to see the effect of sense, feel, act, think, relate on customer loyalty. The variables sense, feel, act, think and relate are part of the customer experience which are the independent variables, while the variable customer loyalty is the dependent variable. The object of this research is the visitors to the hoka-hoka bento restaurant or what is known as hokben. The target respondents for this study were 70 people spread across four hokben outlets in the South Jakarta area. The results of the study show that the variables sense, act and relate have a positive effect on customer loyalty in Hokben restaurant, while the variables feel and think do not have a significant effect on customer loyalty. The most dominant dimension of customer experience in this study is shown in the act experience variable.abstrakPenelitian ini bertujuan untuk melihat pengaruh antara sense, feel, act, think, relate terhadap loyalitas pelanggan. Variabel sense, feel, act, think dan relate adalah bagian dari customer experience yang menjadi variabel independen, sedangkan variabel loyalitas pelanggan adalah sebagai variabel terikat. Adapun objek penelitian ini adalah pengunjung restoran hoka-hoka bento atau yang dikenal hokben. Target responden untuk penelitian ini berjumlah 70 orang yang tersebar di empat gerai hokben di wilayah Jakarta Selatan. Hasil peneltian menunjukan bahwa variabel sense, act dan relate berpengaruh positif terhadap loyalitas pelanggan restoran hokben sedangkan variabel feel dan think tidak berpengaruh signifikan terhadap loyalitas pelanggan. Dimensi customer experience dalam penelitian ini yang paling dominan ditunjukan pada variabel act experience.
The Russian vision of strategic balance in the 21st century in the spirit of political realism
Authors: Kaszuba Malina 
Published: January 2022

Over the past two decades, Russian foreign policy has evolved significantly. Its aim is to seek a change in the global balance of power. This evolution proceeded from attempts to establish cooperation with the West, through a confrontational narrative, ending with political and military actions. The purpose of this article is to analyze the present Russian view of the current international order and to define its future shape based on assumptions and specific actions in the sphere of the aforementioned foreign policy. Particularly useful for the needs of the conducted research is the reference to the theory of political realism. This is determined by the fact that the Russian Federation, contesting the current hegemonic international order, aims to create a multipolar world with the key balancing role of the great powers.
Analiza kulturowo-cywilizacyjna publicznego dyskursu łamania prawa w Rosji i na Ukrainie
Authors: Leszczak Oleg , Prosianyk Oksana 
Published: January 2022

The paper focuses on the notion of legal culture in anthropocentric depiction as an informational-semiotic function. The authors present a typology of cultural-civilisational motives for breaking the law. A range of cultural-civilisational motives (naturalistic, turanic, byzantinic, theocratic, europeistic, and consumerist) expressed in the form of discursive statements was presented in detail; these motives cause breaking the law in a causal synergetic mode (ignorance of the law) and in a cybernetic mode (disregard for the law). The authors distinguish several types of verbal excuses for breaking the law widespread in Russian and Ukrainian legal culture discourse.
Plasma Cytokines Profile in Subjects with Alzheimer’s Disease: Interleukin 1 Alpha as a Candidate for Target Therapy
Authors: Mahdavi Meisam , Karima Saeed , Rajaei Shima , Aghamolaii Vajihe , Ghahremani Hossein , Ataeia Reza , Sepasi Tehrani Hessam , Mahmoodi Baram Somayeh , Tafakhori Abbas , Safarpour Lima Behnam , Shateri Somayeh , Fatemi Hamid , Mokhtari Farzad , Nikzameer Abdolrahim , Yarhosseini Amir , Gorji Ali 
Published: January 2022

Background: Alzheimer’s disease (AD) is the main cause of the neurodegenerative disorder, which is not detected unless the cognitive deficits are manifested. An early prediagnostic specific biomarker preferably detectable in plasma and hence non-invasive is highly sought-after. Various hypotheses refer to AD, with amyloid-beta (Aβ) being the most studied hypothesis and inflammation being the most recent theory wherein pro-and anti-inflammatory cytokines are the main culprits. Materials and Methods: In this study, the cognitive performance of AD patients (n=39) was assessed using mini-mental state examination (MMSE), AD assessment scale-cognitive subscale (ADAS-cog), and clinical dementia rating (CDR). Their neuropsychiatric symptoms were evaluated through neuropsychiatric inventory–questionnaire (NPI-Q). Moreover, plasma levels of routine biochemical markers, pro-/anti-inflammatory cytokines such as tumor necrosis factor α (TNF-α), interleukin-1 α (IL-1α), IL-1β, IL-2, IL-4, IL-6, IL-8, IL-12p70, IL-10, Interferon-gamma, chemokines, including prostaglandin E2 (PGE-2), monocyte chemoattractant protein-1, interferon gamma-induced protein 10, Aβ peptide species (42, 40) and Transthyretin (TTR) were measured. Results: Our results revealed that Aβ 42/40 ratio and TTR were correlated (r=0.367, P=0.037). IL-1α was directly correlated with ADAS-cog (r=0.386, P=0.017) and Aβ 40 (r=0.379, P=0.019), but was inversely correlated with IL-4 (r=-0.406, P=0.011). Negative correlations were found between MMSE and PGE2 (r=-0.405, P=0.012) and TNF-α/ IL-10 ratio (r=-0.35, P=0.037). CDR was positively correlated with both PGE2 (r=0.358, P=0.027) and TNF-α (r=0.416, P=0.013). There was a positive correlation between NPI-caregiver distress with CDR (r=0.363, P=0.045) and ADAS-cog (r=0.449, P=0.019). Conclusion: Based on the observed correlation between IL-1α, as a clinical moiety, and ADAS-cog, as a clinical manifestation of AD, anti-IL-1α therapy in AD could be suggested. [GMJ.2021;10:e1974]
Shockwave Therapy Versus Dry Needling for the Management of Iliotibial Band Syndrome: A Randomized Clinical Trial
Authors: Maghroori Razie , Karshenas Leila , Khosrawi Saied 
Published: January 2022

Background: Iliotibial band syndrome (ITBS) is a common leading cause of lateral knee pain. Despite varieties of medical and non-medical treatments proposed for the management of ITBS, the best therapeutic approach for its treatment remained a significant question. The current study aims to compare the outcomes of dry needling (DN) versus shockwave therapy (SWT) in the management of ITBS.
Materials and Methods: This randomized clinical trial was conducted on 40 patients diagnosed with ITBS. The patients were randomly divided into two treatment groups of DN (n=20) and SWT (n=20). Visual analog scale for the pain assessment, Lower Extremity Functional Scale (LEFS) for the function evaluation, and length of the iliotibial band were assessed at baseline, immediately after the cessation of the intervention, and within four weeks.
Results: The two groups were similar regarding demographic characteristics (P>0.05). Both approaches could efficiently lead to improved pain (P<0.001) and promoted function based on LEFS (P<0.001); however, iliotibial band length (ITBL) did not alter remarkably (P>0.05). The groups were similar in terms of pain score, LEFS, and ITBL at all of the assessment intervals (P>0.05), but the pain score within four weeks following the interventions that were significantly better in DN (P=0.023).
Conclusion: Based on our results, DN, as well as SWT, could remarkably lead to an improvement in pain and function among patients resenting from ITBS; however, none of the approaches was superior over the other. [GMJ.2021;10:e2174]