bluuebunny/crossref_metadata_2025_split huggingface dataset:
New coronavirus infection in a child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia
Authors: Bezrodnova S. M. , Yatsenkо N. A. , Sirazhov G. M. , Kashina Yu. N. 
Published: October 2022

Children are more likely to have asymptomatic and mild forms of novel coronavirus infection, as well as a more favorable outcome of the disease compared to adult patients. Children account for about 15% of all cases of COVID-19 recorded in the country. There are more and more reports of severe and even fatal cases of a new coronavirus infection in children. The development of severe forms of COVID-19 is typical for children at risk. Of particular interest are special groups of pediatric patients, such as children with immunodeficiencies of various etiologies.A clinical case of a new coronavirus infection with a fatal outcome in a 10-year-old child with severe secondary immunodeficiency associated with hematopoietic stem cell transplantation against the background of acute lymphoblastic leukemia is presented.
A case of chickenpox with multiple bacterial complications requiring surgical treatment
Authors: Molochkova O. V. , Kovalev O. B. , Luzan P. Yu. , Ilyina N. O. , Ganiev Sh. A. , Konovalov A. K. , Shamsheva O. V. , Egorova N. Yu. , Zotova A. D. , Rossina A. L. , Korsunskiy A. A. , Galeeva E. V. , Guzhavina A. A. , Tebenkov A. V. , Shatalov V. G. 
Published: October 2022

Chickenpox is a controlled infection, even a single vaccination effectively prevents the development of severe forms (up to 98%).Purpose — to demonstrate a case of severe chicken pox in a child aged 3.8 years with secondary infection of the skin of the right subscapular region and subcutaneous fat (phlegmon of the trunk) of streptococcal etiology.The diagnosis of varicella was confirmed by the detection of Varicella-Zoster virus DNA by PCR from the skin. Surgical treatment was performed — opening and drainage of phlegmon, purulent-serous discharge was obtained, sowing was performed, Streptococcus pyogenes was isolated.The child received antibiotic therapy — cefepime sulbactam, amikacin, acyclovir, infusion therapy, local treatment.Conclusions. The given clinical case demonstrates the development of a severe bacterial complication of chicken pox, which required surgical treatment and substantiates the need for vaccination against chicken pox and its possible complications.
Development of acute renal failure in a child with a generalized form of yersiniosis infection
Authors: Bogvilene Ya. A. , Martynova G. P. , Stroganovа M. A. , Lapteva A. A. 
Published: October 2022

Yersinia infection continues to be a significant problem in infectology due to the prevalence, polymorphism of clinical manifestations, difficulties in laboratory diagnosis, often severe and complicated course of the disease, and the possibility of adverse outcomes.The article presents a clinical case of a generalized form of yersinia infection with the development of acute renal failure in a 10-year-old child.
Arbovirus fevers in children and adults in the Astrakhan region: clinical cases
Authors: Kimirilova O. G. , Kharchenko G. A. 
Published: October 2022

Natural focal infections with transmissible transmission caused by viruses of West Nile Fever, Batai, Inco, Sindbis, Tyagin are registered in various territories of Russia, in the form of sporadic cases, characterized by polymorphism of clinical symptoms, from inapparent forms to severe, occurring with Central nervous system damage (meningitis, meningoencephalitis), which complicates the timely diagnosis and treatment of this pathology.Purpose: to describe our own clinical observations of five cases of arbovirus fevers.Results. Arbovirus fevers (West Nile Fever, Batai, Inko, Tyaginya) in the five clinical cases we have presented occurred in two clinical forms: catarrhal with hypertension syndrome, febrile fever and intense headache, vomiting in the absence of signs of inflammation in the CSF; and with damage to the central nervous system (meningitis). Catarrhal forms of arboviral fevers must be differentiated from ARVI, influenza, mononucleosis. Arbovirus fevers occurring with Central nervous system lesions (meningitis) had a significant similarity with enteroviral meningitis, both in terms of seasonality and clinical symptoms.Conclusion. In the territories of Russia endemic for mosquito fevers, in the summer period of the year, febrile patients with cerebral symptoms and / or meningeal symptoms should be examined for a group of arbovirus fevers.
El personal docente y la calidad en la educación superior: el Centro Universitario de la Costa
Authors: Gómez Chávez Lino Francisco Jacobo , Cortés Almanzar Paola , Rodríguez Melchor Vilma Zoraida del Carmen 
Published: October 2022

A partir de la década de 1990 surgieron políticas públicas e institucionales para el aseguramiento de la calidad en las instituciones de educación superior, situación que, en la actualidad, configura la educación superior en México y gran parte del mundo. El objetivo de este artículo fue analizar la calidad del personal docente de tiempo completo del Centro Universitario de la Costa (CUCosta) de la Universidad de Guadalajara. Para ello, se realizó un estudio a partir de bases de datos institucionales. La población de estudio fue el personal docente del CUCosta. Solo se consideraron los profesores de tiempo completo (137). Se realizaron análisis descriptivos de los indicadores: profesores con doctorado, con perfil deseable del Programa para el Desarrollo Profesional Docente, miembros de cuerpos académicos, así como miembros del Sistema Nacional de Investigadores. Posteriormente, se realizaron análisis por subconjuntos (departamentos); para finalizar, se propone un índice de calidad del personal docente por departamento. Entre los resultados destaca que 64.2 % del personal docente de tiempo completo cuentan con doctorado, 81.7 % cuentan con perfil deseable, 82.4 % pertenecen a un cuerpo académico; solo 35.0% del personal docente pertenece al Sistema Nacional de Investigadores. Las profesoras presentan mejores indicadores en el grado académico, mientras que los profesores destacan en perfil deseable, pertenencia a cuerpo académico y al Sistema Nacional de Investigadores. En relación al índice de calidad del personal docente por departamento, Ciencias Biológicas, Psicología y Estudios Socioeconómicos se ubican en los primeros lugares. Este estudio permite ubicar el estado de los indicadores de calidad del personal docente del CUCosta, los cuales muestran una cultura institucional de apego a las políticas públicas mexicanas de aseguramiento de la calidad de la educación superior, manifiestas tanto en el grado de doctorado, el perfil deseable, pertenencia a cuerpos académicos y al Sistema Nacional de Investigadores.
Update of Lumpy Skin Disease: Emergence in Asian Part of Eurasia
Authors: Saltykov Yuri V. , Kolosova Anna A. , Feodorova Valentina A. 
Published: October 2022

Abstract
Lumpy skin disease (LSD) is an infectious disease mostly of cattle. The typical clinical picture is usually characterized by the appearance of multiple nodules on the skin and internal organs. They can cover the entire body of the animal in the course of severe illness. This disease causes serious economic damage despite the fact that mortality of cattle with LSD is often low. Now LSD is a serious danger for cattle in the Asian part of Russia (part of the territory of the Russian Federation geographically belonging to Asia) and the Southeast Asia. Initially LSD was an endemic disease in many Sub-Saharan African countries, then it spread to Asia and Europe. In order to prevent the spread of the lumpy skin disease virus (LSDV), strict quarantine is introduced, vector control is carried out and various other LSD control measures are implemented. An effective vaccination campaign is required to significantly reduce the morbidity. However, the risk of spreading this transboundary disease to neighboring LSDV virus-free countries and regions of Asia, remains high enough. This article contains a summary of the available information about the spread of LSD in Asian part of Eurasia for the period of 1984 - February 2022. We are also discussing the latest available findings on the epidemiology of LSD and the methods currently used for the prevention and control of the LSDV.
Traumatic Coxofemoral Luxation in Cats Treated with Hip-Toggle Stabilization Using the Mini Tightrope® Fixation System
Authors: Tamburro Roberto , Pratesi Andrea , Carli Fabio , Collivignarelli Francesco , Bianchi Amanda , Paolini Andrea , Falerno Ilaria , De Bonis Andrea , Vignoli Massimo 
Published: October 2022

Abstract
The aim of this retrospective study was to evaluate the clinical and radiographic outcomes of 21 cats that underwent coxofemoral toggle stabilization using the Mini TightRope® Fixation System (mTR®). Data were compiled from client-owned cats with traumatic hip luxation. Each cat underwent the same protocol including orthopedic assessment, preoperative radiographic evaluation, surgical procedure, postoperative management and clinical re-examination at 14 days, 8 weeks and 12 months following surgery. Age, body weight, implants and osteoarthritis progression were recorded. A lameness score 0-4 was assigned to each cat. Pain upon hip extension was not quantified but as pain reaction or no pain reaction. Major complications and osteoarthritic (OA) changes were recorded. Osteoarthritic changes were classified on a 0-4 scale. Twenty-one cats were included in the study. Coxofemoral luxations were stabilized using a mTR®. At 8 weeks, weight bearing was considered normal (grade 0) in all cats and no pain reaction was elicited during hip extension. One year after surgery, orthopedic examination was within the normal limits and according to the owners, all animals exhibited a normal physical activity. No complications were recorded. Evidence of slight OA changes were observed in 5 out of 21 cats. The final outcome was considered excellent in 16/21 patients and good in 5/21 cats. The application of the mTR® system can be considered a suitable surgical treatment in cats affected by traumatic hip luxation.
Homocysteine Concentration in the Serum of Dogs Naturally Infected with Leishmania Spp. – Association with the Stage of the Disease, Therapy, and Clinical Pathology Data
Authors: Antić Milutin , Beletić Anđelo , Radaković Milena , Spariosu Kristina , Stanković Sanja , Trailović Dragiša , Kovačević Filipović Milica 
Published: October 2022

Abstract
Progressive tissue injury in canine leishmaniosis (CL) is related to the deposition of immune complexes, which induces vasculitis and leads to endothelial dysfunction. Homocysteine (Hcy) increase may worsen endothelial dysfunction, but data concerning its concentration in different CL stages and links to the acute phase response and oxidative stress are missing. We compared Hcy levels between dogs with mild (N=24) and moderate CL without treatment (N=17) and treated with anti-Leishmania drugs and vitamin B supplements (N=9). Dogs with moderate CL, regardless of therapy administration, had more distinct clinical signs, lower erythron values, and a higher level of acute-phase proteins (APPs), IgG against Leishmania spp., urea and creatinine, than dogs with mild CL. Hcy values did not differ between stages, but treated dogs had the lowest levels of Hcy. An inverse relationship existed between Hcy and the CL stage, therapy, levels of IgG, and clinical pathology data. The only positive relationship existed between Hcy and the erythron state. The disease stage and therapeutic intervention were not related to the oxidative stress level, except in the case of paraoxonase-1/Hcy ratio, indicating favorable conditions for antioxidative defense in treated dogs. In conclusion, changes in Hcy levels indicated its possible involvement with endothelial dysfunction and inverse relationship to tissue injury evaluated by APPs. Finally, Hcy might be an early marker of favorable conditions for endothelium recovery in CL.
Clinical, Pathological and Molecular Findings in Caprine Arthritis – Encephalitis Virus Infection in Damascus Goats
Authors: Eroksuz Yesari , Timurkan Mehmet Ozkan , Karabulut Burak , Incili Canan Akdeniz , Baydar Ersoy , Cevik Aydin , Eroksuz Hatice 
Published: October 2022

Abstract
Caprine Arthritis-Encephalitis Virus Infection was presented with clinical, pathological, and molecular findings in dairy goats from a breeding unit in Turkey. According to history, 50 of 700 goats and kids showed the clinical signs including anorexia, mastitis, swelling of the joints, lameness, dyspnea and head pressing in the past 2 months. Fifteen and 6 animals were examined clinically and pathologically, respectively. Clinical examination revealed depression, weakness, pneumonia, ataxia and paresis in 15 goats. Histological lesions were composed by a varying degree of interstitial pneumonia, nonsuppurative leukoencephalomyelitis, interstitial nephritis and interstitial myocarditis. Immunohistochemical examinations showed the presence of viral antigen in tubular epithelium, in glial cells and macrophages.
In conclusion, this is the first report documenting pathological and molecular changes of Caprine Arthritis-Encephalitis Virus Infection in Turkey in goats.
Spatiotemporal Distributions of Foot and Mouth Disease Between 2010-2019 in Turkey
Authors: Bayir Tuba , Gürcan İ. Safa 
Published: October 2022

Abstract
Foot and mouth disease (FMD) is one of the most contagious diseases of livestock with a significant economic impact affecting most countries in the world over the years. In Turkey, FMD is endemic, but there have not been national studies conducted to analyze spatiotemporal pattern of FMD yet. This study was carried out to identify the spatial and temporal distribution of FMD outbreaks in Turkey from January 2010 to December 2019, to guide the eradication following development of control programs against the disease. Thematic maps were produced to determine FMD sensitive regions and Box-Jenkins time series approach was used to analyze the temporal pattern of FMD. Between these dates, 6698 outbreaks and 246341 cases were reported in Turkey, FMD was recorded multiple times in 96.3% of the provinces (n = 78), and the average incidence of FMD outbreaks at the provincial level was calculated as 8.27/province year. As result of the spatial pattern of FMD, East and Central Anatolia were determined as the regions where the disease was observed intensely. The time series plot of the data showed a general not very regular trend although there was a downward trend with irregular variations. Although, there was no seasonal effect detected by the decomposition of time series, seasonal peaks in the outbreaks were observed, in the spring (n = 2087, 31.16%). In conclusion, the evaluation of spatial and temporal pattern based on FMD outbreaks that are common in Turkey will contribute to eradication of the disease.
Impact of the Plant-Based Natural Supplement Imмunostart Herb on Honey Bee Colony Performance
Authors: Shumkova Rositsa , Balkanska Ralitsa , Salkova Delka , Hristov Peter 
Published: October 2022

Abstract
Winter is the season that poses the greatest challenges for honey bee colonies. Therefore, the main approach in beekeeping practice is aimed mainly at providing sufficient quality food supplies for bee colonies in early autumn. We conducted the present study to test the influence of the natural plant extract IMМUNOSTART HERB on population strength, stored pollen area, capped worker brood area, and honey yield. The experimental groups were supplied with IMМUNOSTART HERB 4 times at 7-day intervals, whereas sugar syrup was given to the control groups. The obtained results showed that the applied supplemental diet affected all investigated biological parameters, with the most noticeable effect after the second application. In all measurements, the honey bee colony parameters in the treated groups showed higher values in comparison to the control groups. These results highlight the potential of herbal supplements to effectively improve bee colonies’ development during the period of scarce bee forage, as well as to provide suitable conditions for successful overwintering.
Optimization of a Two-Step Centrifugation Protocol for Bovine Platelet-Rich Plasma
Authors: Kim Mu-Young , Han Hyun-Jung 
Published: October 2022

Abstract
Platelet-rich plasma ( PRP), an autologous platelet concentrated in plasma, is a source of diverse growth factors and is extensively utilized to promote tissue healing. Most of the clinical and laboratory investigations in veterinary medicine have focused on horses and dogs. Consequently, the types and detailed conditions of the PRP preparation method are based on those species. However, in bovine medicine, only a few studies have investigated the species-specific characteristics of bovine platelets. The aim of this study was to optimize the conditions of a two-step centrifugation method for bovine PRP. Whole blood samples were obtained from eight healthy lactating Holstein-Friesian cows. Eight running conditions for the first and second centrifugations each were evaluated based on the platelet recovery rate, the concentration of growth factors, and the adenosine diphosphate (ADP)-induced aggregation response, which reflects the premature platelet activation caused by the centrifugation process. The results of this study showed that for the first and second centrifugations, 900×g for 10 minutes and 1250×g for 15 minutes, respectively, were the most suitable conditions for the platelet recovery rate, and the concentration of growth factors was highest under these conditions without significant activation of premature platelet aggregation. Thus, we established an optimal two-step centrifugation protocol for bovine PRP that should provide a better understanding of bovine platelets.
Mammary Adenoma Associated with Chronic Mastitis in a Wild Boar (Sus Scrofa)
Authors: Baek Su-Min , Lee Seoung-Woo , Park Jin-Kyu 
Published: October 2022

Abstract
Mammary gland tumor is rare and only a few cases have been reported in wild animals. Moreover, most etiologies of the known cases in veterinary medicine are related to age, diet, obesity, and excessive sex hormones in domestic animals while few etiologies are reported in wild animals. An unknown-aged female wild boar was presented to the Department of Veterinary Pathology, Kyungpook National University with a well-demarcated, and firm-to-elastic mammary gland mass. The cut-surface of the mass was pink-reddish, and homogeneous. Microscopically, the mass was mainly composed of well-differentiated neoplastic glandular epithelial cells characterized by a single-layer, columnar to cuboidal shapes, and small and central nuclei and nucleoli. Any evidence of invasiveness or metastases of the neoplastic cells were not observed. Interestingly, infiltration of chronic inflammatory cells such as plasma cells and macrophages was observed along with a large quantity of gram-negative and positive bacterial colonies in the mammary glands. Moreover, accompanied fibrosis of stroma was observed, as well. Based on the gross and microscopic findings, the present case was diagnosed as mammary simple adenoma caused by chronic mastitis progressing to fibrotic condition. To the authors’ knowledge, this is the first study describing the histopathological aspects of mammary gland tumors associated with chronic mastitis accompanied by fibrosis in wild animals.
Symmetric Dimethylarginine is a Promising Biomarker for the Early Detection of Age-Related Kidney Dysfunction in Zoo Felids
Authors: Youn Soong-Hee , Efladl Ahmed K. , Chung Myung-Jin , Jung Eun , Shin Ki-Yong , Shin Hyeon-Joo , Yang Joon-Young , Heo Kwang-Seok , Chung Dong-Hee , Yim Jae-Hyuk , Son Ji-Yoon , Lee Eun-Joo , Hong Il-Hwa , Jeong Kyu-Shik 
Published: October 2022

Abstract
Chronic renal failure is one of the leading causes of death in African lions, cheetahs, and tigers. Conventional methods to measure renal dysfunction include measuring serum creatinine and blood urea nitrogen (BUN). Symmetric dimethylarginine (SDMA) measurement is a reliable predictor of renal dysfunction in the domestic cat because SDMA serum levels increase early when the kidneys are damaged. Serum SDMA levels were assessed and correlated with creatinine as well as BUN from healthy captive Bengal tigers and lions at the Everland Zoo in Korea. Serum SDMA concentrations were increasingly associated with increased age in lions. However, SDMA concentrations were higher in some young Bengal tigers than in older ones, which may allow for earlier renal dysfunction detection in these young cats than would be BUN and creatinine alone. In Bengal tigers, the correlation between the SDMA and BUN was slightly higher than that between SDMA and creatinine. In lions, SDMA correlated better with creatinine than with BUN concentration. These results show that serum SDMA concentration can be used as a biomarker for age-associated renal dysfunction. SDMA measurement may be an essential preventive management method in zoos.
Chinese-English Contrastive Translation System Based on Lagrangian Search Mathematical Algorithm Model
Authors: Shi Xianglin 
Published: October 2022

Abstract
The English-Chinese machine translation system is a current research topic. This paper designs an English-Chinese comparison system based on Lagrangian search mathematical algorithm. This paper proposes a Lagrangian algorithm to describe the English short syntax and improves the English-Chinese translation algorithm. When expanding nodes, the algorithm expands on the inspiration node and expands on other nodes. The experimental results show that the improved Lagrangian search algorithm can obtain better translation results and search efficiency in the system.
Research on mobile Awareness service and data privacy Protection based on Linear Equations computing protocol
Authors: Yu Juan , Shatat Abdallah Saleh 
Published: October 2022

Abstract
In the steady development of social economy, in order to solve the data privacy problem of mobile sensing service of Internet of Things and improve the service level of practical system operation, it is not only necessary to comprehensively master the acquisition process of static information and dynamic information, but also to combine the protection status of previous Internet of Things technology and sensing data. Deeply explore how to ensure the confidentiality, integrity and controllability of mobile awareness services and related data privacy. In this paper, we study the knowledge of the parsing process of system of linear equations, the system studied the movement perception service framework and data privacy security requirements, is proposed for mobile data privacy protection model of perceived service, has been clear about the mobile service perception model and the application of data privacy protection algorithm, it not only conforms to the protection of the Internet of things moving perceived service requirements, It can also provide basic guarantee for the application of perceptual data in modern development.
Scientific Model of Vocational Education Teaching Method in Differential Nonlinearity
Authors: Gao Fanxiu , Liu Fulian , Aldulaimi Saeed Hameed 
Published: October 2022

Abstract
This paper uses nonlinear differential equations to establish a relationship model between enrollment, education, and employment in vocational education. In this paper, the local stability of the vocational education system is analyzed utilizing nonlinear differential theory and numerical simulation. At the same time, we carried out a numerical simulation of the system’s dynamic behavior. Through numerical simulation research, it is found that the model has peculiar nonlinear behavior and dynamic characteristics when its parameters take some specific values. Finally, we get the critical condition of the stability of the vocational education system according to the model established in the article.