bluuebunny/crossref_metadata_2025_split huggingface dataset:
In search of a dialogue: Digital di-plomacy of Sweden
Authors: Marchukov A. N. 
Published: January 2022

Digital diplomacy opens up new opportunities for both developed and devel-oping states to promote their international image, clarify their position on current issues, and realize long-term foreign policy aspirations, but it also brings com-pletely new challenges. The chief one among them is establishing a continuous constructive dialogue with the target audience in the virtual space. Facilitation for this dialogue is one of the key priorities of the digital diplomacy of Sweden. The author examines the activities of the key actors of Sweden’s digital diplomacy (the Ministry of Foreign Aﬀ airs of Sweden, the Swedish Institute, the Swedish Tourist Association (Svenska Turistföreningen), ‘Visit Sweden’) and identiﬁ es their key features. Particularly, the author emphasizes the government’s readiness to implement innovative and creative methods to promote its media projects. The latter include such projects as ‘The Second House of Sweden’, ‘Curators of Sweden’, and ‘Swedish Number’, which were aimed at improving the quality of communication with the foreign audience. In doing so, the responsible minis-tries and agencies placed a heavy emphasis on promoting a dialogue via social networks between the Swedish oﬃ cials and representatives of the civil society on the one hand and foreign users on the other. The leading actors of Sweden’s digital diplomacy actively engaged the foreign audience in discussions on the most important issues on the foreign policy agenda of Sweden. This was most clearly demonstrated in media campaigns designed to eliminate discrimination against women and gender-based violence. The author concludes that Sweden has achieved a certain degree of success in establishing a dialogue with the foreign audience, yet this dialogue is not comprehensive enough and still depends on the initiative of individual politicians and diplomats.
Man against machine: Debates in the expert community on the lethal autonomous systems
Authors: Lipova A. Yu. 
Published: January 2022

In the recent years debates surrounding the autonomous weapons systems development and regulation have gained a new momentum. Despite the fact that the development of such type of weapons continues since the twentieth century, recent technological advances open up new possibilities for development of completely autonomous combat systems that will operate without human in-tervention. In this context, international community faces a number of ethical, legal, and regulatory issues. This paper examines the ongoing debates in both the Western and the Russian expert community on the challenges and prospects for using lethal autonomous systems. The author notes that Russian and Western discourses on most of the issues have very much in common and diﬀ erences are found mainly in the intensity of debates — in the West they are much more ac-tive. In both cases the most active debates focus around two issues: the potential implications of fully autonomous weapons systems including the unclear line of accountability, and the prospects for international legal regulation of the use of lethal autonomous weapons. Both the Russian and the Western experts agree that the contemporary international humanitarian law is unable to handle the challenges posed by aggressive development of the lethal autonomous weapons. All this points to the need to adapt the international humanitarian law to the new realities, which, in turn, requires concerted actions from leading states and international organizations.
Clinical characteristics of patients with subacute thyroidits and factors affecting development hypothyroidism after subacute thyroiditis
Authors: ANAFOROĞLU İNAN , Topbas Murat 
Published: January 2022

IntroductionSubacute thyroiditis (SAT) is typically a self-limiting, inflammatory disease. Patients can experience hypothyroidism during or after an episode. We examined the clinical characteristics based on laboratory and imaging studies in patients with SAT and possible factors contributing to the development of permanent hypothyroidism after SAT.Material and methodsWe retrospectively examined medical records of patients diagnosed with SAT at one medical facility in Turkey. Patients known to have previous thyroid disease, those with <6 months of follow-up after resolution of SAT, and those who lacked sufficient data for analysis were excluded. Of the 283 patients identified 119 met all inclusion criteria.
We extracted data on demographics, laboratory tests, neck pain and other symptoms, ultrasonography findings, medication use, and SAT recurrence. We examined the relationships between these variables and development of permanent hypothyroidism.ResultsThe patients were 42 years old on average, and 78% were women. Most patients (70%) described flu-like symptoms before neck pain started; accordingly, 57% had initially visited a specialty other than endocrinology before SAT was diagnosed, and 28% had received antibiotics for misdiagnosed upper respiratory tract infection. In all, 10 patients (8.4%) developed permanent hypothyroidism after SAT. These patients had received steroids significantly longer than did those without permanent hypothyroidism (mean 17.7 vs. 8.9 weeks; P = .021). Development of hypothyroidism was significantly lower among patients with thyrotoxicosis.ConclusionsThe diagnosis of SAT can be challenging. Patients who require longer-term steroids after SAT and who have recurrent SAT should be closely monitored for development of hypothyroidism.
EARLY WEANING AND THE INFLUENCE ON THE APPEARANCE OF HARMFUL ORAL HABITS:
Authors: Daiane Souto Luz da Silva Anne , Beatriz de Siqueira Melo Galindo Paula , Ciane Silveira Cirino de Britto Galvão Thaís , Machado Lima Brunela 
Published: January 2022

Breastfeeding is essential for the child’s physical and psychological development, contributing to the mother-child relationship, reducing the risks of infections and malnutrition. The present work aims to verify the relationship between early weaning and the appearance of harmful oral habits, through a review of narrative literature, a search was performed in the Bireme, VHL, Pubmed/MEDILINE data bases and virtual library platform my library, in the Portuguese and English languages of the last 16 years. Therefore, it is observerd that there is a direct interconnection between these two aspects, which highlights the importance of health actions aimed at pregnant women and women who have recently given birth.
KHẢO SÁT SỰ HÀI LÒNG CỦA THÀNH VIÊN GIA ĐÌNH NGƯỜI BỆNH ĐỐI VỚI NHÂN VIÊN Y TẾ THUỘC BỆNH VIỆN BỆNH NHIỆT ĐỚI HẢI DƯƠNG NĂM 2019
Authors: Thu Hà Nguyễn , Trọng Hải Trần , Thị Nhuyên Phạm , Như Nguyên Trần , Thị Nguyệt Thanh Phí , Đức Sơn Nguyễn , Thu Hà Nguyễn 
Published: January 2022

Mục tiêu: Đánh giá sự hài lòng của thành viên gia đình người bệnh (TVGĐ NB) với bác sĩ (BS), điều dưỡng (ĐD) và đối với các yếu tố khác thuộc Bệnh viện bệnh Nhiệt đới Hải Dương năm 2019. Đối tượng và phương pháp: Nghiên cứu mô tả cắt ngang 72 thành viên gia đình người bệnh điều trị tại Bệnh viện Nhiệt đới Hải Dương năm 2019. Kết qủa và kết luận: Mức độ hài lòng của TVGĐ NB với BS tại Bệnh viện bệnh Nhiệt đới Hải Dương: khám, giải thích về tình trạng bệnh, chẩn đoán, trực tiếp điều trị là 98,57%. Mức độ hài lòng của TVGĐ NB với ĐD tại Bệnh viện bệnh Nhiệt đới Hải Dương, gồm: phổ biến những thông tin cần thiết khi vào Bệnh viện và trong quá trình điều trị (100%); Có lời nói, cử chỉ, thái độ thân thiện với người bệnh (NB) và TVGĐ NB (98,61%); Tư vấn chế độ chăm sóc NB là (100%); Tận tình giúp đỡ NB, TVGĐ, không gợi ý, đòi tiền quà (97,22 %); Công khai thuốc (95,83%) và hướng dẫn sử dụng thuốc (100%). Mức độ hài lòng của TVGĐ NB với các yếu tố khác của Bệnh viện bệnh Nhiệt đới Hải Dương: Thủ tục hành chính nhanh gọn (100%); Vệ sinh sạch sẽ (94,45%); Cơ sở hạ tầng và trang thiết bị hiện đại (65,28%).
NGHIÊN CỨU MỐI LIÊN QUAN GIỮA CHỈ SỐ ABI, TỐC ĐỘ LAN TRUYỀN SÓNG MẠCH VỚI MỨC ĐỘ TỔN THƯƠNG ĐỘNG MẠCH VÀNH THEO THANG ĐIỂM SYNTAX II Ở BỆNH NHÂN NHỒI MÁU CƠ TIM CẤP
Authors: Đình Linh Nguyễn , Thị Kim Ngân Hồ , Đức Hùng Trần 
Published: January 2022

Mục tiêu: Tìm hiểu mối liên quan giữa chỉ số huyết áp tâm thu cổ chân-cánh tay (Ankle Brachial Index – ABI), tốc độ lan truyền sóng mạch (pulse wave velocity - PWV) với mức độ tổn thương động mạch vành (ĐMV) ở bệnh nhân (BN) nhồi máu cơ tim (NMCT) cấp. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang trên 2 nhóm: nhóm bệnh gồm 60 người bị NMCT cấp và nhóm chứng gồm 33 người có cùng độ tuổi và các yếu tố nguy cơ và chụp ĐMV không tổn thương. Cả 2 nhóm đều được đo ABI, PWV, chụp ĐMV, nhóm bệnh được đánh giá mức độ tổn thương theo thang điểm SYNTAX II. Kết quả: Tuổi trung bình của nhóm bệnh và nhóm chứng tương ứng là 67,05 ± 12,04 và 67,67 ± 6,80 năm. ABI của nhóm bệnh (1,04 ± 0,10) thấp hơn nhóm chứng (1,12 ± 0,13), p<0,01. PWV của nhóm bệnh (15,90 ±1,49 m/s) cao hơn nhóm chứng (13,32 ± 1,98 m/s), p<0,01. PWV ở nhóm tổn thương 1 nhánh và ≥2 nhánh tương ứng là 15,25 ± 1,09 m/s và 16,22 ± 1,57 m/s. Có sự tương quan chặt chẽ giữa PWV với điểm SYNTAX (r = 0,477; p<0,01). Kết luận: ở nhóm NMCT cấp PWV cao hơn và ABI thấp hơn nhóm chứng có ý nghĩa. PWV tương quan chặt chẽ với mức độ tổn thương ĐMV theo thang điểm SYNTAX II.
Molecular docking of lutein as anti-photoaging agent in silico
Authors: Krisnayana I Gede Bayu , Febyani Putu Dewi , Sari Ida Ayu Yadnyaningtias Permata , Laksmiani Ni Putu Linda 
Published: January 2022

The accumulation of UV exposure resulted in the loss of skin elasticity, and the appearance of wrinkles on the skin is commonly known as photoaging. Matrix metalloproteinase-1 (MMP-1) is an enzyme that degrades type I and III fibrillar collagen. This study aims to determine the mechanism of MMP-1 inhibition by lutein, a carotenoid compound with high antioxidant activity, using in silico molecular docking. This study was conducted by optimization of lutein structure using HyperChem 8, preparation of MMP-1 (PDB ID: 966C) using Chimera 1.10.1, validation of the method, and docking lutein against MMP-1 using Autodock 4.2. The results showed lutein had binding energy of -12.28 kcal/mol, lower than RS2 native ligand (-10.83 kcal/mol). The hydrogen bond formed between lutein and MMP-1 through HIS228 residue. To conclude, lutein may be developed as an anti-photoaging agent by inhibiting the MMP-1.
Pemanfaatkan Potensi Lokal Melalui Pembuatan Susu Jagung Guna Mencegah Stunting Pada Desa Gejugan
Authors: Setiyono Agus Edi , Ngatimun Ngatimun , Musriati Titik 
Published: January 2022

Gejugan Village is one of the villages in Probolinggo district on the north coast. Gejugan Village is in the west bordering Klaseman Village and Karangpranti Village, Pajarakan District. Gejugan village has local potential that can be developed from their agricultural produce, namely corn. Corn is an alternative food source that contains many nutrients. But the people here still don't have the knowledge to be able to use it. The Socialization Activity for Making SUJU (Corn Milk) to Prevent Stunting and Utilizing Local Potential is expected to provide more knowledge to the Gejugan community in utilizing existing local potential, especially processing corn into corn milk. Besides having good nutrition, corn milk also has more value in the economy. If it is processed properly and properly, this product can be sold in the market. The socialization of making corn milk was attended by 25 residents of Gejugan Village. Material for making corn milk was given by providing materials and hands-on practice during the event. Participants in the socialization of making corn milk enthusiastically listened to and practiced directly making corn milk during the socialization process. From the results of the socialization, the practiced corn milk resulted in 6 bottles of corn milk measuring 360 ml. Participants listened well and the material presented was well received by all participants present.
Keywords: Local Potential, Corn Milk, Stunting
Upaya Pencegahan dan Pemberdayaan Ekonomi Masyarakat Terdampak Covid-19 di Kecamatan Kademangan Kota Probolinggo
Authors: Mubaroq Husni , Halima Nur 
Published: January 2022

Virus covid-19 merupakan virus yang penyebarannya melalui droplet antarmanusia dan bersentuhan langsung dengan benda yang terpapar virus. Menaiknya kasus aktif covid-19 di Kota Probolinggo khususnya Kecamatan Kademangan dikarenakan masyarakatnya masih kurang informasi mengenai penyebaran dan pencegahan covid-19. Akibatnya banyak masyarakat yang terdampak secara ekonomi dikarenakan pandemi covid-19. Tujuan dari pengabdian masyarakat ini untuk mencegah penyebaran virus covid-19, menumbuhkan pola hidu sehat, serta memberdayakan ekonomi masyarakat yang terdampak covid-19. Mitra pengabdian kami adalah pengelola terminal Bayuangga dan UMKM Bakpia Manalagi. Metode pengabdian pada pengabdian masyarakat berupa edukasi mengenai 3M, dan penyaluran bantuan tempat cuci tangan di Terminal Bayuangga, serta melakukan pemberdayaan ke UMKM Bakpia Manalagi dengan cara membantu perluasan pemasaran dengan metode digital marketing. Dengan pengabdian masyarakat yang sudah dilaksanakan, didapatkan hasil pemahaman mengenai pentingnya melakukan 3M apabila beraktifitas di luar rumah dan dengan melakukan perluasan pemasaran memakai digital marketing mampu menaikkan permintaan produk yang berimbas pada kebutuhan akan karyawan yang dapat memberdayakan masyarakat sekitar.Kata lunci : Covid-19, Pola Hidup Sehat, Digital Marketing, Pencegahan Covid-19, Pemberdayaan Masyarakat
Sub-chronic oral toxicity study of “Kien Nao Dan” tablets in experimental animal
Authors: Hong Trinh Thi Thuy , Xuan Le Thanh , Minh Tran Quang , Hang Vu Viet , Van Anh Pham Thi , Hien Dang Thi Thu 
Published: January 2022

“Kien nao dan” (KND) tablet is composed of 13 traditional medicines that may has preventive and effective treatment of cerebral ischemia. However, there are no scientific reports of its toxicological properties which guarantee of the safety its usage treatment. Therefore, the aim of this study was to investigate the sub-chronic toxicity of KND tablet on rats through oral administration. The sub-chronic toxicity was evaluated by the recommendation of WHO in Wistar rats at doses of 0.72 g/kg/day (equal to recommended human dose) and 2.16 g/kg/day (3 times as high as recommended human dose) for 8 consecutive weeks. In the evaluation of sub-chronic toxicity, there were no behavioral and physiological changes or signs of toxicity. The result of the hematological and biological parameters after administration of KND tablets showed no change. The histopathologic analysis of livers and kidneys indicated that no significant differences were observed between the exposed and unexposed rat groups. In conclusion, “Kien nao dan” tablets did not produce sub-chronic toxicity in Wistar rats.
UV SPECTROPHOTOMETRY IN THE ANALYSIS OF A COMBINED MEDICINAL PRODUCT BASED ON DRY LICORICE ROOT EXTRACT
Authors: ОМАРИ А.М. , АРЫСТАНОВА Т.А. 
Published: January 2022

Работа посвящена разработке методики количественного определения глицирризина и аскорбиновой кислоты при их совместном присутствии в комбинированном лекарственном препарате в виде саше методом УФ-спектрофотометрии.
This paper represents a developed technique for the quantitative determination of a new medicinal composition based on dry licorice extract and ascorbic acid for the prevention and treatment of immunode ciency in viral infections by UV spectrophotometry
THE NEGATIVE IMPACT OF ALIMENTARY OBESITY ON THE STATE OF LOCAL IMMUNITY OF THE VAGINAL MUCOSA AND THE EFFECTIVENESS OF THE THERAPY OF BACTERIAL VAGINOSIS
Authors: ЖУКЕМБАЕВА А.М. , АСАН Б.Н. , АБЫЛГАЗИЕВА А.Т. , АЙТБАЙ А.А. , МУРАТХАН И.Г. , ЖАКСЫЛЫК М.Б. 
Published: January 2022

Проведен анализ результатов стандартного лечения бактериального вагиноза у 143 больных с учетом наличия у них алиментарного ожирения. Все женщины, принимавшие участие в нашем исследовании, дали письменное информированное согласие на участие в нем. Лечение БВ проводилось по общепринятой методике метронидазолом и клиндамицином. В зависимости от наличия алиментарного ожирения больных бактериальным вагинозом разделили на 2 группы. В I группу вошли 97 без алиментарного ожирения. Во II группе у 46 больных отмечалось увеличение массы тела, соответствующее алиментарному ожирению II степени. Исследования проводили до начала лечения и через 14 суток после его завершения. Сравнительный анализ результатов лечения БВ в исследуемых группах показал, что на фоне АО II степени отмечались достоверно более выраженные увеличение количества «ключевых клеток» (P<0,05) и смещение pH в щелочную сторону (P<0,05) во II группе. При этом эффективность лечения у больных II группы, где отмечалось алиментарное ожирение II степени была достоверно меньше, чем в I (P<0,05), что свидетельствовало о негативном влиянии алиментарного ожирения на состояние локального иммунитета слизистой оболочки влагалища и результативность проводимой терапии бактериального вагиноза.
The results of standard treatment of bacterial vaginosis in 143 patients were analyzed, taking into account the presence of alimentary obesity in them. All the women who took part in our study gave written informed consent to participate in it.BV was treated according to the generally accepted method with metronidazole and clindamycin. Depending on the presence of alimentary obesity, patients with bacterial vaginosis were divided into 2 groups. Group I included 97 people without alimentary obesity. In group II, 46 patients had an increase in body weight corresponding to alimentary obesity of the II degree. Studies were conducted before the start of treatment and 14 days after its completion. A comparative analysis of the results of BV treatment in the study groups showed that against the background of grade II AO, there was a significantly more pronounced increase in the number of "key cells" (P<0.05) and a pH shift to the alkaline side (P<0.05) in group II. At the same time, the effectiveness of treatment in group II patients with grade II alimentary obesity was significantly less than in group I (P<0.05), which indicated a negative effect of alimentary obesity on the state of local immunity of the vaginal mucosa and the effectiveness of the therapy of bacterial vaginosis.
Review of the monograph by V.Kh. Akaev "Sufism in the Context of Arab-Muslim Culture. Monograph. Grozny: State Unitary Enterprise "Book Publishing House", 2020. 523 pp."
Authors: Ляушева Светлана Аслановна , Нехай Вячеслав Нурбиевич 
Published: January 2022

Монографическое исследование В.Х. Акаева представляет собой самостоятельное авторское исследование, посвященное проблемам генезиса и эволюции суфизма в глобальном и региональном измерении. Отмечается, что суфизм, сформировавшись в лоне арабо-мусульманской культуры, как религиозно-мистический феномен проник в духовное пространство народов Северного Кавказа. Его отличительной чертой в рассматриваемом регионе стало то, что суфистские братства сумели встроиться в структуру традиционных этносоциальных институций ряда северокавказских народов. Однако деформация общественно-политической жизни Северного Кавказа в начале 1990-х гг. привела к активизации деятельности радикалистов и экстремистов в Чечне и Дагестане. В рецензируемой монографии осмыслен деструктивный потенциал религиозного радикализма, который активно продвигался идеологами ваххабизма, оперировавшими концептами шахидизма. Определены принципиальные расхождения ваххабизма и суфизма в интерпретации теологической доктрины ислама. Отдельного внимания заслуживает и авторское описание социально-политического портрета асоциальных акторов радикализма. Делается вывод о том, что наиболее эффективным инструментом профилактики религиозного радикализма является диалог культур, нацеленный на смягчение культурных конфликтов и обеспечивающий их активный обмен при сохранении культурно-исторической самобытности.
The monographic study of V.Kh. Akaev is an independent author's research on the problems of genesis and the evolution of Sufism in the global and regional dimension. Having formed in the bosom of Arab-Muslim culture, Sufism as a religious-mystical phenomenon penetrated the spiritual space of the peoples of the North Caucasus. Its distinctive feature in the region under consideration was that Sufi fraternities managed to integrate into the structure of traditional ethnosocial institutions of a number of North Caucasian peoples. However, the deformation of the socio-political life of the North Caucasus in the early 1990s led to the activation of the activities of radicalists and extremists in Chechnya and Dagestan. The peer-reviewed monograph makes sense of the destructive potential of religious radicalism, which was actively promoted by Wahhabism ideologists who operated on the concepts of Shahidism. Fundamental differences between Wahhabism and Sufism in the interpretation of the theological doctrine of Islam were determined. The author's description of the socio-political portrait of asocial actors of radicalism deserves special attention. The research shows that the most effective tool for preventing religious radicalism is the dialogue of cultures aimed at mitigating cultural conflicts and ensuring their active exchange while preserving cultural and historical identity.
Think Globally, Start Locally: Value-Based Breast Cancer Care for Newly Diagnosed Patients in A Safety-Net Medical Center
Authors: Tang Annie , Ugarte Shannon R , Khoury Amal L , Gyawali Bishal , Chiang Anna , Lai Nicole , John Rohan E , Bennett Charles , Knopf Kevin 
Published: January 2022

Introduction We assessed the efficacy of a multidisciplinary, patient-focused approach emphasizing appropriate use of medical resources among a population of breast cancer patients at our safety-net hospital. Methods A multidisciplinary program coordinated and provided value-based care. Surgery, oncology, and navigation were physically co-located. Real time decisions were made by medical and surgical oncologists. Focused institution-specific protocols initiated in 2018, advised against four specific cancer resources that our team had determined as lower-value: imaging tests for indications not recommended in NCCN guidelines, inappropriate Oncotype Dx testing, radiation for patients ≥65 years with stage I hormone-positive disease, and administration of pertuzumab and neratinib as adjuvant therapy in HER2+ breast cancer patients. Time to treatment and rates of use of these resources were monitored. Results Newly diagnosed breast cancer patients from 2015-2019 were compared to the pre-protocol era (2015-2017). Time from first breast clinic visit to oncology appointment decreased 39 days (60% decrease, median of 63.0 vs 22.5 days, p<0.001), no patients ≥65 years with stage I hormone-positive breast cancer in 2018-2019 received radiation therapy, and rates of ordering of CT, PET, and bone scans for asymptomatic patients decreased by 80%. Overall survival did not differ by cohort protocol category/treatment choices (p=0.69) Compared to the pre-protocol cohort, the post-protocol cohort did not have a significantly lower risk of death (Hazard Ratio 0.66, 95% Confidence Interval 0.08-5.38, p=0.69). Overall breast cancer care cost decreased by $3,675,374 between 2018 and 2019 versus 2015 to 2017. Conclusions After initiating a breast cancer program focused on reducing rates of use of four commonly excessively ordered breast cancer resources our team identified as lower-value, care at our safety-net hospital achieved high compliance with NCCN maging guidelines and also reduced use of a low-value diagnostic test, and low-value radiation and chemotherapy.