bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adaptive decision support for addiction treatment to implement initiation of buprenorphine for opioid use disorder in the emergency department: protocol for the ADAPT Multiphase Optimization Strategy trial
Authors: Iscoe Mark S , Diniz Hooper Carolina , Levy Deborah R , Buchanan Laurel , Dziura James , Meeker Daniella , Taylor Richard Andrew , D’Onofrio Gail , Oladele Carol , Sarpong Daniel F , Paek Hyung , Wilson Francis P , Heagerty Patrick J , Delgado Mucio Kit , Hoppe Jason , Melnick Edward R 
Published: February 2025

IntroductionDespite the current opioid crisis resulting in tens of thousands of deaths every year, buprenorphine, a medication that can reduce opioid-related mortality, withdrawal, drug use and craving, is still underprescribed in the emergency department (ED) for treatment of opioid use disorder (OUD). The EMergency department-initiated BuprenorphinE for opioid use Disorder (EMBED) trial introduced a clinical decision support (CDS) tool that improved the proportion of ED physicians prescribing buprenorphine but did not affect patient-level rates of buprenorphine initiation. The present trial aims to build on these findings by optimising CDS use through iterative improvements, refined interventions and clinician feedback to enhance OUD treatment initiation in EDs.Methods and analysisThe Adaptive Decision support for Addiction Treatment (ADAPT) trial employs the Multiphase Optimization Strategy (MOST) framework to refine a multicomponent CDS tool designed to facilitate buprenorphine initiation for OUD in ED settings. Using a pragmatic, learning health system approach in three phases, the trial applies plan–do–study–act cycles for continuous CDS refinement. The CDS will be updated in the preparation phase to reflect new evidence. The optimisation phase will include a 2×2×2 factorial trial, testing the impact of various intervention components, followed by rapid, serial randomised usability testing to reduce user errors and enhance CDS workflow efficiency. In the evaluation phase, the optimised CDS package will be tested in a randomised trial to assess its effectiveness in increasing ED initiation of buprenorphine compared with the original EMBED CDS.Ethics and disseminationThe protocol has received approval from our institution’s institutional review board (protocol #2000038624) with a waiver of informed consent for collecting non-identifiable information only. Given the minimal risk involved in implementing established best practices, an independent study monitor will oversee the study instead of a Data Safety Monitoring Board. Findings will be submitted to ClinicalTrials.gov, published in open-access, peer-reviewed journals, presented at national conferences and shared with clinicians at participating sites through email notification.Trial registration numberNCT06799117.
UK defence rehabilitation review of Achilles and patellar tendinopathy conservative management: a systematic review
Authors: Judd Alice , Wild K , Puxley L , Barker-Davies R 
Published: February 2025

IntroductionTendinopathy is a common condition affecting physically active populations, such as the military. Diagnosis is clinical, with no gold-standard tests. The role of imaging and functional assessment in subdiagnosis is an active area of research with the hope of delivering more nuanced and clinically effective management. A vast array of injectable and adjunctive therapies have been proposed with varying, and at times, conflicting evidence. Multiple methods for exercise therapy exist, but increasingly tendinopathy is recognised as a heterogeneous condition not suited to a one-size-fits-all approach. The aim was to complete a systematic review, to appraise the recent evidence for conservative management of Achilles and patellar tendinopathy.MethodsA multidisciplinary team from across defence rehabilitation searched PubMed for literature dating from May 2017 to July 2023. Four key areas were searched: diagnosis and outcome measures, medical, exercise and adjuncts.ResultsA total of 840 articles were identified. Articles were screened using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Following screening and abstract review, a total of 143 were included for full review. Due to the breadth of literature and large heterogeneity of studies, meta-analysis of results was not feasible. Articles were assessed against the Oxford Centre for Evidence Based Medicine criteria.ConclusionsThe literature review found the strongest evidence for exercise-based rehabilitation as first-line treatment, with limited evidence for medical interventions and adjuncts. The primacy of stand-alone loading modalities is challenged by developing literature supporting a progressive tendon loading exercise protocol (PTLE). PTLE represents a framework where various exercise modalities are prescribed based on the individual’s capacity and function. Novel interventions should be practised with caution and not conducted as monotherapy.
Thermodynamic properties of a Gaussian quantum ring in the presence of a molecular ion
Authors: Sakiroglu S. , Tuzemen A. Turker , Türk G. Eyceyurt , Sari H. 
Published: February 2025

Abstract
In this study, the findings of research conducted into the thermodynamic properties of a molecular complex ion in a 2D quantum ring characterized by Gaussian-type potentials are presented. The Schrödinger equation for a singly ionized double donor complex was solved by a two-dimensional diagonalization method. The results obtained show that at the internuclear distance, where there is coupling between the Coulomb centers such that the electron is shared by both impurity atoms, the mean energy and entropy of the system are minimal. A further finding is that in the regime where the distance between impurity atoms is comparable to the inner radius of the quantum ring, the heat capacity of the system undergoes significant changes with temperature.
Identifying Equivalent Circuits of Electrochemical Impedance Spectroscopy Using CNN-LSTM
Authors: Yang Changjiang , Gao Bo-bin , Chang Jun , Zhang Li-hua 
Published: February 2025

Abstract
Electrochemical impedance spectroscopy (EIS) is widely utilized in electrochemical studies, and equivalent circuits are usually the first and crucial step in analyzing impedance data. In this study, an artificial intelligence (AI)-driven approach combining convolution neural network (CNN) and long short-term memory (LSTM) is proposed to identify equivalent circuits. The simulated data were preprocessed to construct a dataset for the CNN to extract the characteristic EIS feature. The stacked LSTM network was used to detect the in-depth sequence features of the EIS, and then the equivalent circuit recognition result was obtained. Initial experiments indicate that compared with standalone CNN, LSTM, and their improved models, the accuracy of CNN-LSTM model reaches 93.27%, and the accuracy, recall and F1 score improved by at least 1.11 %,0.87 % and 0.66 %, respectively. Finally, the model was further validated using impedance data from lithium-ion batteries, demonstrating consistent probability distributions of equivalent circuits compared to circuit fitting results. These findings confirm the effectiveness of CNN-LSTM model in identifying equivalent circuit models for EIS data.
Inka Numbers, Khipu, and Yupana: a Reanalysis
Authors: Florio Cinzia , Overmann Karenleigh A. 
Published: February 2025

Abstract
We review the history of decipherment on the technologies used for numbers by the Inkas – khipus and yupanas. We offer a novel interpretation of the portable “checkerboard” yupana drawn in 1615, revealing a numerical algorithm. This analysis sheds new light on the Inka number system, questioning its inclusion of a concept of zero and its interpretation as a positional system. We conclude that Inka numbers and computational methods were likely non-positional, analogous to Mesopotamian, Egyptian, Greek, and Roman numbers. We show the Inka multiplication method as similar to – but more efficient than – the Egyptian method in the Rhind Papyrus. This analysis shows the Inka number system to have ranked among the great mathematical traditions of the ancient world.
Emotional Processing and Acculturation
Authors: Cruz Ana , Rosa Catarina , Bem-Haja Pedro 
Published: February 2025

Abstract
This work intended to analyse how Chinese people who have different degrees of exposure to Portuguese language make affective assessments of the emotional dimensions of audio stimuli in both Mandarin Chinese and European Portuguese. A sample of 23 native Chinese speakers with different levels of proficiency in Portuguese evaluated the affective valence and physiological arousal of a set of 10 negative, 10 positive, and 10 neutral words, presented in three different versions: a) in Portuguese spoken by a native speaker; b) in Portuguese spoken by a Chinese individual; c) and in Mandarin Chinese spoken by a native speaker. Our results reveal an interesting effect of increasing time of learning of Portuguese. The effects of prosody versus content in perception of emotional speech are verified. A brief analysis on emotional production in a foreign language is also included.
Challenges to International Negotiations Amidst Unstable Global Dynamics
Authors: Spector Bertram I. 
Published: February 2025

Abstract
In a world that is moving from a rules-based international order to one that is more multi-polar, confrontational, and uncertain, international negotiation processes must adapt to the changing context. Negotiators must navigate and adjust in an environment that can be disrupted by changing power dynamics, emerging technologies such as artificial intelligence, global pandemics, increasing inequalities, illiberal regimes, and climate change, to name just a few. This 30th anniversary issue of International Negotiation explores international negotiation within this volatile context, including what some call a “gathering global disorder.” This article examines the impacts of the current global disorder in the context of two very different cases: the Israel-Gaza conflict and the ongoing implementation of the United Nations Convention Against Corruption (uncac).
Exploration and Exploitation of Seabed Minerals in the Tanzanian Maritime Zones and Beyond the Limits of National Jurisdiction
Authors: Mtavangu Vicent Bartholomew 
Published: February 2025

Abstract
Tanzania is one of the coastal states of the Indian Ocean. It is also an active state party to the United Nations Convention on the Law of the Sea (UNCLOS). This international instrument regulates, among others, the exploration and exploitation of seabed minerals, especially in the deep sea. Tanzania has promulgated a law to implement the UNCLOS. Additionally, the country has various regulations to fully benefit from the marine mineral resources found in its maritime domain. However, the existing legal framework does not adequately and comprehensively cover the exploration and exploitation of seabed minerals within the Tanzanian maritime zones and beyond the limits of national jurisdiction, the Area. This means that the current pieces of legislation only and partly touch on mining activities within the territorial sea, continental shelf and the EEZ. None of them regulates seabed mining in the Area. Thus, this article discusses the need for Tanzania to enact comprehensive and adequate legal frameworks governing seabed mining in its maritime zones and the Area.
Revisiting the African Union’s Strategy on Unconstitutional Changes of Governments in Africa
Authors: Mavedzenge Justice Alfred 
Published: February 2025

Abstract
In recent years, Africa has experienced a spike in successful and attempted military coups. This has once again generated debate on the African Union’s approach to the problem of unconstitutional changes of government. This article contributes to this debate by identifying emerging trends of unconstitutional changes of government and analysing the African Union’s response to these trends. The article argues that electoral coups and constitutional coups appear to be the most prevalent forms of unconstitutional changes of governments in Africa. However, the African Union is pre-occupied with military coups while ignoring electoral coups and constitutional coups. This approach is both conceptually and practically defective because it undermines efforts to build democracy on the continent. The African Union has mischaracterized some recent military coups as unconstitutional changes of government. Yet, conceptually, these coups are unconstitutional power grabs which are not necessarily unconstitutional changes of government. By being fixated with military coups while ignoring constitutional and electoral coups, the African Union’s strategy fails to appreciate the nexus between constitutional and electoral coups on the one hand and military coups, on the other hand.
Molecular phylogenetic analysis and taxonomy of the Palearctic Pamphagidae grasshoppers (Orthoptera, Acridoidea) based on DNA markers
Authors: Sukhikh Igor , Bugrov Alexander , Chobanov Dragan , Fet Victor , Biryukov Mikhail , Blinov Alexander 
Published: February 2025

Abstract
Achieving a commonly accepted phylogeny of the grasshopper family Pamphagidae proves to be challenging using only morphology-based analysis. So far, discussions about status and phylogenetic placement of taxa within this family did not yield a clear picture of evolutionary history of the Pamphagidae. However, a large amount of DNA sequences has been amassed in the available databases, offering a good opportunity to utilize molecular methods to clarify phylogenetic relationships among the Pamphagidae.
Analyzing sequences of two mitochondrial genes, COI and COII, we constructed a new phylogenetic tree for three (out of five) subfamilies of the Pamphagidae. Total of 83 Pamphagidae species were used in the analysis. These subfamilies form six clades; while most species fall into their recognized genera and tribes, the relationships between some tribes and subfamilies fail to concur with a currently accepted phylogeny. Our data suggest a separate position of the tribe Tropidauchenini as opposed to the rest of the subfamily Pamphaginae, while the tribe Nocarodeini appears to represent a higher taxonomic rank than a tribe, which might suggest its possible position as subfamily. The current paper is the first step on a road to a comprehensive phylogenetic study of the Pamphagidae family. The differences in commonly accepted classification compared to our data suggests that further study is necessary to uncover true evolutionary story of this complex family of Orthoptera insects.
Jesuit Connoisseurs and Collectors of Ancient Coins before Joseph Eckhel
Authors: Awianowicz Bartosz B. 
Published: February 2025

Abstract
As early as 1635, Jesuit Claude Clément (1596–1642) recognized coins as “minted historical sources” and an essential complement to the library. However, it was not until the latter half of the seventeenth century that Jesuits became prominent members of the “Republic of Medals,” the European network of coin and medal connoisseurs and collectors. This article aims to explore the varied contributions of Jesuits to numismatics up to the mid-eighteenth century. Among the first prominent figures were the French Jesuits Louis Jobert (1637–1719), a collector of ancient coins and author of the bestseller La science des médailles (The science of medals), and Jean Hardouin (1646–1729), a controversial scholar who employed ancient coins to to study historical chronology. In the eighteenth century, the most significant numismatic works were produced by Viennese Jesuits: Erasmus Frölich (1700–58), Joseph Khell von Khellburg (1714–72), and later, Joseph Eckhel (1737–98). Preceding them, the Jesuits of Graz published Synopsis rei nummariae veterum (Synopsis of the monetary system of the ancients; 1724), a unique numismatic textbook written in hexameter. Jesuits also maintained substantial institutional and private collections, particularly within their colleges.
Effects of Exercise Training on Body Composition and Exercise Capacity After Bariatric Surgery: A Systematic Review and Meta-Analysis
Authors: Li Jingru , Jo Unyong 
Published: February 2025

Purpose Bariatric surgery is a widely used treatment for obesity; however, it may be associated with certain complications. Effective postoperative management, including lifestyle interventions and exercise training, is essential for optimal outcomes. This study explores the effectiveness of exercise training in postoperative care. Methods We searched PubMed, Web of Science, Cochrane, and Embase up to April 3, 2024. Articles were screened and data extracted based on inclusion/exclusion criteria. Risk of bias was assessed using RoB 2.0, and data were analyzed with Stata 15.0. Results Twenty-three articles involving 1940 patients were included; 16 were analyzed quantitatively. Exercise training did not significantly reduce body weight compared to routine care (WMD: −0.26; 95% CI, −2.11 to 1.58; I2 = 54%), but it significantly reduced fat mass (WMD: −2.42; 95% CI, −3.50 to −1.34; I2 = 42.9%) and maintained lean mass (WMD: 1.40; 95% CI, 0.32 to 2.48; I2 = 0.0%). Additionally, it reduced waist circumference (WMD: −2.58; 95% CI, −4.43 to −0.73; I2 = 13.4%) and improved exercise capacity (VO₂ max: WMD: 1.88; 95% CI, 0.64 to 3.13; I2 = 0.0%). Conclusion While exercise training did not significantly lower body weight post-surgery, it effectively reduced fat mass, maintained lean mass, and improved waist circumference and exercise capacity. Given the limited sample sizes in most studies, further large-scale controlled trials are warranted for more definitive conclusions, along with further consideration of their long-term impact on health metrics.
Isokinetic profile of the wrist flexors and extensors in young women and men
Authors: Shemy Eitan , Okada Takashi , Arnon Michal , Peleg Smadar 
Published: February 2025

Background Isokinetic studies of wrist flexion and extension (WFE) have been conducted mostly in the concentric mode. However, the eccentric counterpart is of specific importance in strength profiling while both modes are differently expressed in women and men. Objective to characterize the isokinetic concentric and eccentric isokinetic strength of the dominant side WFE, in a group of healthy young women and men and explore their respective internal and external relationships. Methods 20 women and 20 men were tested while standing with forearm in neutral position, using a RoM of 60° and a speed of 120°/s for both contraction modes. Isometric grip strength was measured using a standard apparatus. Results Men were significantly stronger than women, the flexors significantly stronger than the extensors and the eccentric strength significantly higher than its concentric counterpart. A correlation matrix based on the concentric and eccentric peak moments of the WFE revealed that men had significantly higher correlation coefficients compared to women. Conclusions While supporting the efficiency of the test position, the significant sex-related difference in the strength correlations pattern may reflect an acquired-adaptive trait but this assumption requires further research.
Palpation-based scapular dyskinesis test: Inter-and intra-rater reliability and clinical advantages
Authors: Kim Jian , Kim Young Kyun 
Published: February 2025

Background The Scapular Dyskinesis Test (SDT) is typically conducted using either real-time visual observation or video analysis. However, factors such as restricted shoulder mobility, higher body mass index (BMI), patient-centred care, and cultural considerations may impact the reliability of SDT results. Palpation offers an alternative approach that addresses these limitations by providing additional tactile information on joint function and dysfunction. Objective This study aimed to evaluate the reliability and potential benefits of the palpation-based SDT. Methods Videotaped, real-time visual observation, and palpation-based SDTs were conducted on 55 patients to assess the reliability and potential advantages of the palpation technique. Results The inter-rater reliability of the palpation-based SDT was almost perfect ( k = 0.82), while intra-rater reliability was similarly high ( k = 0.97). Additionally, eight patients diagnosed with scapular dyskinesis (SD) were found to have Scapular Snapping Syndrome (SSS). Conclusion The palpation-based SDT demonstrated superior inter-rater reliability compared to video analysis and real-time visual observation, with almost perfect reliability ( k = 0.82). This method is particularly beneficial for patients with high or low BMI, those unable to remove clothing, and may be useful for detecting SSS. The findings suggest that palpation SDT is an effective tool for assessing scapular dyskinesis in various clinical settings.
BRAF inhibitors with or without MEK inhibitors in advanced BRAF-positive non-small cell lung cancer: A systematic review
Authors: Saha Animesh , Raja T , Dutt Dwary Amit , Ghosh Indranil , Narayan Mahapatra Prabrajya , Mukhopadhay Tanmoy 
Published: February 2025

Objective About 1% to 5% of cases of non-small cell lung cancer (NSCLC) have been found to have a BRAF mutation. There is no phase III data, despite the fact that numerous phase II and retrospective studies have demonstrated the efficacy of single agent BRAF inhibition and combination BRAF/MEK inhibition in patient groups that have received treatment and those who have not. Our goal in this systematic review was to provide an overview of the available evidence in this context. Data Sources A thorough search was conducted in the PubMed, Medline, Embase, and Cochrane databases for English-language papers published between January 2000 and December 2023 that had full text accessibility. Independently, one author screened the eligible studies that fit our predetermined requirements. A synthesis of the qualitative data was conducted, and the design and quality of the studies were evaluated. Data Summary There were 2952 articles found using the search method. Twelve publications with a total of 753 patients were included after two rounds of screening. 33–75% was the objective response rate (ORR). 64–100% was the disease control rate (DCR). The time span for the answer varied from 6.4 to 16.7 months. The range of the median progression-free survival (PFS) was 1.2 to 17.5 months. The range of the median overall survival (OS) was 1.7–25.5 months. When comparing studies with single agent BRAF inhibitors to those reporting the results of BRAF plus MEK inhibitors, the response rates, duration of response, and survival were better in the former case. When untreated patients receiving BRAF/MEK inhibitor therapy were compared to previously treated patients, the results were also improved. Hypertension, pyrexia, hyponatremia, neutropenia, dyspnoea, anaemia, abnormal liver function, asthenia, and cutaneous epidermoid carcinoma were among the frequently reported grade ≥3 toxicity. Conclusions Patients with advanced NSCLC that include a BRAF mutation have demonstrated encouraging clinical outcomes with a manageable safety profile when treated with BRAF inhibitors, either in combination with or without MEK inhibitor therapy. In patients who had not received treatment before, combination treatment produced greater results.