bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developmental life stages of the Pickersgill's reed frog (Hyperolius pickersgilli) in an ex‐situ environment at Johannesburg Zoo's captive breeding facility, South Africa
Authors: du Plessis Ian , Armstrong Adrian , Malepa Piet L. , Kanengoni Arnold T. , Price Cormac , Downs Colleen T. 
Published: March 2022

AbstractGlobally, the threats of habitat loss and disease on amphibian survival have necessitated the creation of ex‐situ insurance populations as a conservation tool. We initiated a captive breeding project to create an insurance population for the endangered Pickersgill's reed frog (Hyperolius pickersgilli Raw, 1982) at the Johannesburg Zoo from parents collected from KwaZulu‐Natal Province, South Africa, in 2017. We found that this species has seven developmental life stages, each with unique management requirements. The quiescent tadpoles hatched 6–8 days after the eggs were laid and remained at this stage for 2 days. The next stage, the developing tadpoles, showed no form of cannibalism or carrion feeding. The external appearance of the first leg (the right hind) occurred 5–6 weeks after the tadpoles hatched, and the metamorph stage was reached after 7–8 weeks. The metamorph stage lasted 3–5 days, after which tail resorption was complete and the froglet stage reached. Froglets could not be sexed externally, although body color changed based on the amount of light present at the resting place. Sub‐adults were 6 months and older with adult coloration and sex differentiation visible even with color change. Adults were older than 18 months and fully developed and sexually mature, displaying amplexus, oviposition, and external fertilization. A greater understanding of Pickersgill's reed frog's developmental stages and physiological and environmental needs can improve captive breeding and subsequent release of the frogs, facilitate captive breeding elsewhere, and improve the species’ conservation status.
„Resuscitative endovascular balloon occlusion of the aorta“ bei schwer verletzten Patienten im Schockraum: eine Fallserie
Authors: Knapp Jürgen , Jakob Dominik A. , Haltmeier Tobias , Lehmann Beat , Hautz Wolf E. 
Published: March 2022

ZusammenfassungEine Hämorrhagie ist in 30–40 % der Patienten, die im Rahmen eines Traumas versterben, todesursächlich und die häufigste vermeidbare Todesursache. Für nichtkomprimierbare Blutungen im Bereich des Abdomens oder des Beckens wird in den letzten Jahren zunehmend (wieder) die Anwendung der „resuscitative endovascular balloon occlusion of the aorta“ (REBOA) zur temporären Blutungskontrolle diskutiert. Seit August 2020 steht im Schockraum des Universitären Notfallzentrums des Universitätsspital Bern die REBOA als Therapieoption im Rahmen der Schwerverletztenversorgung zur Verfügung. Wir berichten in dieser Fallserie unsere Erfahrungen aus allen 7 Anwendungen im Laufe des ersten Jahres.
Harnessing the diversity of wild emmer wheat for genetic improvement of durum wheat
Authors: Balla Mohammed Yousif , Gorafi Yasir Serag Alnor , Kamal Nasrein Mohamed , Abdalla Modather Galal Abdeldaim , Tahir Izzat Sidahmed Ali , Tsujimoto Hisashi 
Published: March 2022

Abstract
Key message
The multiple derivative lines (MDLs) characterized in this study offer a promising strategy for harnessing the diversity of wild emmer wheat for durum and bread wheat improvement.

Abstract
Crop domestication has diminished genetic diversity and reduced phenotypic plasticity and adaptation. Exploring the adaptive capacity of wild progenitors offer promising opportunities to improve crops. We developed a population of 178 BC1F6 durum wheat (Triticum turgidum ssp. durum) lines by crossing and backcrossing nine wild emmer wheat (T. turgidum ssp. dicoccoides) accessions with the common durum wheat cultivar ‘Miki 3’. Here, we describe the development of this population, which we named as multiple derivative lines (MDLs), and demonstrated its suitability for durum wheat breeding. We genotyped the MDL population, the parents, and 43 Sudanese durum wheat cultivars on a Diversity Array Technology sequencing platform. We evaluated days to heading and plant height in Dongola (Sudan) and in Tottori (Japan). The physical map length of the MDL population was 9 939 Mb with an average of 1.4 SNP/Mb. The MDL population had greater diversity than the Sudanese cultivars. We found high gene exchange between the nine wild emmer accessions and the MDL population, indicating that the MDL captured most of the diversity in the wild emmer accessions. Genome-wide association analysis identified three loci for days to heading on chromosomes 1A and 5A in Dongola and one on chromosome 3B in Tottori. For plant height, common genomic loci were found on chromosomes 4A and 4B in both locations, and one genomic locus on chromosome 7B was found only in Dongola. The results revealed that the MDLs are an effective strategy towards harnessing wild emmer wheat diversity for wheat genetic improvement.
Linear programming feedrate optimization
Authors: Petráček Petr , Vlk Bořivoj , Švéda Jiří 
Published: March 2022

AbstractThis paper focuses on two aspects of feedrate optimization via linear programming methods. Namely, the effect of curve sampling on time optimality of the resultant feedrate profile and a method of feedrate profile adaptation in response to a feedrate override command. A comparison of three distinct curve sampling approaches (uniform in parameter, uniform in arc length and curvature adaptive) is performed on a series of standard tool path curves. Results show that the curvature-adaptive sampling approach leads to substantial machining time reduction for tool path curves displaying high degree of curvature variation. Secondly, a method by which a new feedrate profile can be calculated in response to a feedrate override command is developed. The method formulates a new set of boundary conditions on the control point sequence of the feedrate curve in such a way that the resulting profile is guaranteed to coincide with the currently active profile up to the moment of override command, while minimizing the arc length necessary for transition to the newly commanded feedrate.
The p-adic Corlette–Simpson correspondence for abeloids
Authors: Heuer Ben , Mann Lucas , Werner Annette 
Published: March 2022

AbstractFor an abeloid variety A over a complete algebraically closed field extension K of $$\mathbb {Q}_p$$

Q
p

, we construct a p-adic Corlette–Simpson correspondence, namely an equivalence between finite-dimensional continuous K-linear representations of the Tate module and a certain subcategory of the Higgs bundles on A. To do so, our central object of study is the category of vector bundles for the v-topology on the diamond associated to A. We prove that any pro-finite-étale v-vector bundle can be built from pro-finite-étale v-line bundles and unipotent v-bundles. To describe the latter, we extend the theory of universal vector extensions to the v-topology and use this to generalise a result of Brion by relating unipotent v-bundles on abeloids to representations of vector groups.
Care reality of menopausal women in Germany: healthcare research using quantitative (SHI claims data) and qualitative (survey) data collection
Authors: Stute Petra , Eversheim Helena , Ortius-Lechner Diethe , May Melanie , Feig Chiara 
Published: March 2022

Abstract
Purpose
The transition from the fertile phase of life to menopause is associated with numerous physical changes. Hormone replacement therapy (HRT), as the most effective and efficient form of drug treatment, involves the use of oestrogens and progestins with the aim of increasing health-related quality of life through symptom reduction, sleep improvement and affect enhancement.

Methods
The medical care situation and disease burden of menopausal women was investigated by means of a survey of 1000 women aged 45–60 years on the topics of quality of life, menopause and HRT and a quantitative, longitudinal healthcare study based on an anonymised and age- and sex-adjusted Statutory Health Insurance (SHI) routine data set with approximately four million anonymous insured persons per year.

Results
Out of more than half a million women aged 35–70 years, and with statutory health insurance, (n = 613,104), 14% (n = 82,785) had climacteric disorder documented as a first diagnosis in 2014. The proportion of women with the climacteric disorder, who were prescribed HRT on an outpatient basis, was 21%; according to the forsa survey, 50% of the women surveyed felt moderate to poorly/very poorly informed about treatment options.

Conclusion
Findings from the health insurance research conducted with different data sources (survey and SHI claims data) indicate the need for increasing awareness and providing an early and informative education on HRT and its risks and benefits.
Outcomes and complications of cataract surgery in patients with chronic ocular graft-versus-host-disease—a multicenter, retrospective analysis
Authors: Gehlsen Uta , Faust Christiane , Blecha Christiane , Dietrich-Ntoukas Tina , Eberwein Philipp , Issleib Susanne , Meyer-ter-Vehn Tobias , Braun Regine , Westekemper Henrike , Steven Philipp 
Published: March 2022

Abstract

Purpose

To evaluate the outcome of phacoemulsification in patients with chronic ocular Graft-versus-host disease (oGVHD) after allogeneic hematopoietic stem cell transplantation (aHSCT).

Methods
Retrospective, observational multicenter study from 1507 oGVHD patients. From the patient files, data were collected including best-corrected visual acuity (BCVA), intraocular pressure (IOP), Schirmer’s test I, tear film break-up time (TFBUT), corneal fluorescein staining score, postoperative complications, and pre- and post-operative topical therapy.

Results
Seventy-three patients underwent cataract surgery in 104 eyes. In n = 84 eyes, the oGVHD NIH grade was documented; 12% (n = 12) of analyzed eyes were staged oGVHD NIH grade 1, 31% (n = 32) NIH 2 and 39% (n = 41) NIH 3. The mean BCVA improved in 82% of the eyes (n = 86 eyes). BCVA significantly increased from 0.7 ± 0.5 to 0.4 ± 0.4 LogMAR after surgery independent from oGVHD severity. The mean IOP decreased from 14 ± 4 to 13 ± 4 mmHg after surgery. Visual acuity was moderately correlated to the pre-operative degree of corneal staining (Pearson p = 0.26, p = 0.002, Cohen’s effect size f = 0.29). The visual acuity decreased by 0.078 LogMar units (95% CI = 0.027–0.141) with each increase of corneal staining by one grade (p = 0.05). After surgery, corneal epitheliopathy increased significantly in 42% (n = 44) of the eyes. Postoperative complications included corneal perforation (n = 6, 6%), cystoid macular edema (n = 4, 4%), and endophthalmitis (n = 1, 1%).

Conclusion
Phacoemulsification in patients with chronic oGVHD significantly improves visual acuity, but is associated with an increased risk of complications in particular corneal epitheliopathy and corneal perforations.
Carbazochrome sodium sulfonate is not effective for prevention of post-gastric endoscopic submucosal dissection bleeding: A retrospective study
Authors: Takahashi Keitaro , Sasaki Takahiro , Ueno Nobuhiro , Uehara Kyoko , Kobayashi Yu , Sugiyama Yuya , Murakami Yuki , Kunogi Takehito , Ando Katsuyoshi , Kashima Shin , Moriichi Kentaro , Tanabe Hiroki , Okumura Toshikatsu , Fujiya Mikihiro 
Published: March 2022

Abstract
Background
Carbazochrome sodium sulfonate (CSS) is conventionally administered to prevent post-endoscopic submucosal dissection (ESD) bleeding in many institutions, but research on its preventive efficacy is lacking. Therefore, we investigated the risk of post-ESD bleeding and the preventive efficacy of CSS administration.

Methods
We retrospectively reviewed 304 lesions in 259 patients with gastric neoplasms who underwent ESD at Asahikawa Medical University Hospital from 2014 to 2021. In the CSS group, CSS 100 mg/day was intravenously infused with maintenance fluid replacement on postoperative days 0–2. The risk factors of post-ESD bleeding, including CSS administration, were investigated.

Results
The overall rate of post-ESD bleeding was 4.6% (14/304). The univariate analysis showed that atrial fibrillation (Af), warfarin intake, heparin replacement, and tumor location in the lower third were significant risk factors for increasing the likelihood of postoperative bleeding. In the multivariate analysis, Af (odds ratio [OR] 3.83, 95% CI 1.02–14.30; p < 0.05), heparin replacement (OR 4.60, 95% CI 1.02–20.70; p < 0.05), and tumor location in the lower third of the stomach (OR 6.67, 95% CI 1.43–31.00; p < 0.05) were independent factors for post-ESD bleeding. Post-ESD bleeding was observed in 5.2% (9/174) of the CSS group and 3.8% (5/130) of the non-CSS group, with no significant difference between the two groups (p = 0.783). Additionally, CSS was not shown to have preventive effects in groups with higher-risk factors, such as Af diagnosis, warfarin use, heparin replacement, and tumor location in the lower third of the stomach.

Conclusion
CSS administration was not effective for the prevention of the post-ESD bleeding in the overall patient population as well as in higher-risk patients. This suggests that the administration of CSS for post-ESD bleeding prevention may need to be reconsidered.
FDG-PET/CT for oral focus assessment in head and neck cancer patients
Authors: Schwaninger Dominic Raphael , Hüllner Martin , Bichsel Dominique , Giacomelli-Hiestand Barbara , Stutzmann Nicole Selina , Balermpas Panagiotis , Valdec Silvio , Stadlinger Bernd 
Published: March 2022

Abstract

Objectives
To compare oral and maxillo-mandibular inflammatory foci on standard oral radiographs (OPT, periapical radiograph) with available fluorine-18-labelled fluoro-2-deoxy-D-glucose-positron emission tomography/computed tomography (FDG-PET/CT) data and to discuss whether additional metabolic information derived from FDG-PET/CT can support oral care specialists when performing oral focus examinations.

Materials and methods
Data from 23 patients with head and neck cancer who underwent FDG-PET/CT and panoramic and periapical radiography in close succession before first-line radiotherapy and/or chemotherapy were included in this exploratory retrospective study. Periapical lesions and marginal periodontal inflammation on FDG-PET/CT scans and standard oral radiographs were analysed and compared with regard to metabolic activity on FDG-PET/CT in comparison to recorded clinical symptoms and radiological scores. Additionally, inflammatory maxillo-mandibular pathologies were analysed using FDG-PET/CT.

Results
The maximum standardised uptake value (SUVmax) in FDG-avid marginal periodontal sites could not be conclusively associated with the radiologically recorded severity of marginal bone loss, but a potential positive correlation was identified. No association was found either between the metabolic activity of periapical lesions and their extent, as recorded on standard oral radiographs, or regarding clinical symptoms (percussion test). Most maxillo-mandibular pathologies did not show increased FDG uptake.

Conclusions
FDG-PET/CT provided additional metabolic information that can help clinicians identify lesions with increased inflammatory activity. The incorporation of available oral FDG-PET/CT findings into the primary oral focus assessment may allow for more accurate oral focus treatment.

Clinical relevance
FDG-PET/CT provides valuable metabolic information for oral care specialists. The detection of inflammatory oral processes using FDG-PET/CT facilitates treatment.
A Bayesian approach to model individual differences and to partition individuals: case studies in growth and learning curves
Authors: Mezzetti Maura , Borzelli Daniele , d’Avella Andrea 
Published: March 2022

AbstractThe first objective of the paper is to implement a two stage Bayesian hierarchical nonlinear model for growth and learning curves, particular cases of longitudinal data with an underlying nonlinear time dependence. The aim is to model simultaneously individual trajectories over time, each with specific and potentially different characteristics, and a time-dependent behavior shared among individuals, including eventual effect of covariates. At the first stage inter-individual differences are taken into account, while, at the second stage, we search for an average model. The second objective is to partition individuals into homogeneous groups, when inter individual parameters present high level of heterogeneity. A new multivariate partitioning approach is proposed to cluster individuals according to the posterior distributions of the parameters describing the individual time-dependent behaviour. To assess the proposed methods, we present simulated data and two applications to real data, one related to growth curve modeling in agriculture and one related to learning curves for motor skills. Furthermore a comparison with finite mixture analysis is shown.
Semantic feature activation takes time: longer SOA elicits earlier priming effects during reading
Authors: Hofmann Markus J. , Kleemann Mareike A. , Roelke-Wellmann André , Vorstius Christian , Radach Ralph 
Published: March 2022

AbstractWhile most previous studies of “semantic” priming confound associative and semantic relations, here we use a simple co-occurrence-based approach to examine “pure” semantic priming, while experimentally controlling for associative relations. We define associative relations by the co-occurrence of words in the sentences of a large text corpus. Contextual-semantic feature overlap, in contrast, is defined by the number of common associates that the prime shares with the target. Then we revisit the spreading activation theory and examine whether a long vs. short time available for semantic feature activation leads to early vs. late viewing time effects on the target words of a sentence reading experiment. We independently manipulate contextual-semantic feature overlap of two primes with one target word in sentences of the form pronoun, verb prime, article, adjective prime and target noun, e. g., "She rides the gray elephant." The results showed that long-SOA (verb-noun) overlap reduces early single and first fixation durations of the target noun, and short-SOA (adjective-noun) overlap reduces late go-past durations. This result pattern can be explained by the spreading activation theory: The semantic features of the prime words need some time to become sufficiently active before they can reliably affect target processing. Therefore, the verb can act on the target noun's early eye-movement measures presented three words later, while the adjective is presented immediately prior to the target—thus a difficult adjective-noun semantic integration leads to a late sentence re-examination of the preceding words.
An atomistic view on the uptake of aromatic compounds by cyclodextrin immobilized on mesoporous silica
Authors: Kraus Hamzeh , Hansen Niels 
Published: March 2022

AbstractThe effect of immobilized $$\upbeta$$
β
-cyclodextrin (bCD) molecules inside a mesoporous silica support on the uptake of benzene and p-nitrophenol from aqueous solution was investigated using all-atom molecular dynamics (MD) simulations. The calculated adsorption isotherms are discussed with respect to the free energies of binding for a 1:1 complex of bCD and the aromatic guest molecule. The adsorption capacity of the bCD-containing material significantly exceeds the amount corresponding to a 1:1 binding scenario, in agreement with experimental observations. Beside the formation of 1:2 and, to a lesser extent, 1:3 host:guest complexes, also host–host interactions on the surface as well as more unspecific host–guest interactions govern the adsorption process. The demonstrated feasibility of classical all-atom MD simulations to calculate liquid phase adsorption isotherms paves the way to a molecular interpretation of experimental data that are too complex to be described by empirical models.
Global Poverty and Kantian Hope
Authors: Blöser Claudia 
Published: March 2022

AbstractDevelopment economists have suggested that the hopes of the poor are a relevant factor in overcoming poverty. I argue that Kant’s approach to hope provides an important complement to the economists’ perspective. A Kantian account of hope emphasizes the need for the rationality of hope and thereby guards against problematic aspects of the economists’ discourse on hope. Section 1 introduces recent work on hope in development economics. Section 2 clarifies Kant’s question “What may I hope?” and presents the outlines of his answer. Crucially, hope is rational if it is rational to trust in the structures of reality on which the realization of one’s hope depends. Section 3 argues that central tenets of Kant’s account of what makes hope rational can be applied to the context of poverty. It becomes apparent that the poor often have good reason to be hopeless since they may not trust fundamental structures that are necessary for realizing their hope. Thus, the insight that the poor need more hope must go hand in hand with a commitment to establishing trustworthy political structures, such that their hope can be rational. Section 4 highlights the relevance of the secular highest good for a better understanding of the justification and scope of our duties to the poor in a Kantian framework.
Underground LoRa Sensor Node for Bushfire Monitoring
Authors: Herring Ben , Sharp Tony , Roberts Tim , Fastier-Wooller Jarred , Kelly Greg , Sahin Oz , Thiel David , Dao Dzung , Woodfield Peter L. 
Published: March 2022

AbstractThe feasibility of an underground LoRaWAN bushfire temperature sensing node from the point of view of survivability in a bushfire event is considered. Thermal penetration into the soil is modelled using a one-dimensional analytical formulation for a semi-infinite solid. A working prototype of the sensor unit was tested experimentally beneath a relatively small (400 mm × 400 mm base) timber fire. A buried LoRa radio (depth 100 mm) with a k-type thermocouple monitored the temperature from beneath the fire. The analysis demonstrates that under dry soil conditions, the time that the sensor node under the fire base can endure is proportional to the square of the depth of burial of the electronic components and inversely proportional to the thermal diffusivity of the soil. The original contribution of the work is in the practical demonstration of the durability of a LoRa sensing node beneath a fire front for bushfire sensing applications.
sMARE: a new paradigm to evaluate and understand query performance prediction methods
Authors: Faggioli Guglielmo , Zendel Oleg , Culpepper J. Shane , Ferro Nicola , Scholer Falk 
Published: March 2022

AbstractQuery performance prediction (QPP) has been studied extensively in the IR community over the last two decades. A by-product of this research is a methodology to evaluate the effectiveness of QPP techniques. In this paper, we re-examine the existing evaluation methodology commonly used for QPP, and propose a new approach. Our key idea is to model QPP performance as a distribution instead of relying on point estimates. To obtain such distribution, we exploit the scaled Absolute Ranking Error (sARE) measure, and its mean the scaled Mean Absolute Ranking Error (sMARE). Our work demonstrates important statistical implications, and overcomes key limitations imposed by the currently used correlation-based point-estimate evaluation approaches. We also explore the potential benefits of using multiple query formulations and ANalysis Of VAriance (ANOVA) modeling in order to measure interactions between multiple factors. The resulting statistical analysis combined with a novel evaluation framework demonstrates the merits of modeling QPP performance as distributions, and enables detailed statistical ANOVA models for comparative analyses to be created.