bluuebunny/crossref_metadata_2025_split huggingface dataset:
LncRNA MAGI2-AS3 Inhibits Prostate Cancer Progression by Targeting
the miR-142-3p
Authors: Hu Renbao , Wu Pei , Liu Jianhui 
Published: August 2022

AbstractProstate cancer is a common male cancer with high morbidity and mortality
worldwide. According to current research, the integration of long non-coding RNA
(lncRNAs) and microRNA(miRNAs) can be expressed in a variety of cancers and play
an important role in diagnosis. Based on this, this study explored the clinical
role of lncRNA MAGI2-AS3 (MAGI2-AS3) in prostate cancer. By detecting the
expression levels of MAGI2-AS3 and miR-142-3p, the correlation between the
MAGI2-AS3 expression and the characteristics of clinical data was analyzed. ROC
curve analysis was performed and the area under the ROC curve (AUC) was used to
evaluate the diagnostic value of MAGI2-AS3 in distinguishing prostate cancer
patients from healthy controls. The function of MAGI2-AS3 in prostate cancer
cells was explored through CCK-8 and Transwell assays, and the relationship
between MAGI2-AS3 and miR-142-3p was investigated by luciferase activity assay.
MAGI2-AS3 has descended expression while miR-142-3p has an ascendant one in
prostate cancer serum samples and cells. ROC curve analysis revealed that the
AUC was 0.953 for MAGI2-AS3, with a sensitivity of 91.5% and specificity
of 84.7%. Overexpression of MAGI2-AS3 in LNCaP and PC3 cells suppressed
the biological function of the cell including proliferation capacity, migration
level, and invasion. MAGI2-AS3 was considered a diagnostic biomarker for
prostate cancer patients and inhibited prostate cancer progression by targeting
miR-142-3p.
Comparison of Different Concentrations of Ropivacaine Used for Ultrasound-Guided Adductor Canal Block + IPACK Block in Total Knee Arthroplasty
Authors: Wang Qiuru , Hu Jian , Ma Ting , Zhao Dongmei , Yang Jing , Kang Pengde 
Published: August 2022

AbstractThis study aimed to compare the analgesic efficacy of different concentrations of ropivacaine used for the combination of ultrasound-guided adductor canal block (ACB) and infiltration between the popliteal artery and capsule of the posterior knee (IPACK) block in total knee arthroplasty (TKA). Before general anesthesia, 90 patients undergoing TKA were randomized to receive ACB + IPACK block with ropivacaine 0.2, 0.25, or 0.3% (defined as group A, B, and C, respectively). Primary outcome was the reported visual analog scale (VAS) pain scores at rest 30 minutes following arrival to the postanesthesia care unit (PACU). Secondary outcomes were postoperative VAS pain scores, postoperative morphine consumption, the time to first rescue analgesia, functional recovery of knee (including the range of motion and quadriceps strength), and postoperative complications. Compared with group A, group B and group C had significantly lower VAS scores 30 minutes following arrival to the PACU (p < 0.001 and p < 0.001, respectively). These two groups also had significantly lower VAS pain scores at postoperative 2 hours (at rest: p = 0.037 and 0.002; during motion: p = 0.035 and 0.001, respectively) and 6 hour (at rest: p = 0.033 and 0.002; during motion: p < 0.001 and p < 0.001, respectively), lower postoperative morphine consumption (p = 0.001 and 0.002, respectively), longer time to first rescue analgesia (p = 0.010 and 0.009, respectively), and better range of knee motion on the day of surgery (p = 0.008 and 0.002, respectively). Group B and group C showed no significant differences in these outcomes between each other (p > 0.05). The three groups did not show a significant difference in postoperative quadriceps strength and complication rates (p > 0.05). Compared with ropivacaine 0.2%, ropivacaine 0.25 and 0.3% can provide early pain relief in the first 6 hours after surgery. Ropivacaine 0.25 and 0.3% may provide more clinical benefits for patients undergoing outpatient TKA.
Size Comparison of the Cadaveric Anterior Cruciate Ligament Midsubstance Cross-Sectional Area and the Cross-Sectional Area of Semitendinosus Double-Bundle Anterior Cruciate Ligament Reconstruction Autografts in Surgery
Authors: Yahagi Yoshiyuki , Iriuchishima Takanori , Iwama Genki , Suruga Makoto , Horaguchi Takashi , Aizawa Shin , Nakanishi Kazuyoshi 
Published: August 2022

AbstractThe purpose of this study was to compare the cadaveric midsubstance cross-sectional anterior cruciate ligament (ACL) area and the cross-sectional semitendinosus (ST) double-bundle ACL autograft area in surgery. Thirty-nine nonpaired formalin-fixed cadaveric knees and 39 subjects undergoing ST double-bundle ACL reconstruction were included in this study. After soft tissue resection, cadaveric knees were flexed at 90 degrees, and the tangential line of the femoral posterior condyles was marked and sliced on the ACL midsubstance. The cross-sectional ACL area was measured using Image J software. In the patients undergoing ACL surgery, the harvested ST was cut and divided into anteromedial (AM) bundle and posterolateral (PL) bundle. Each graft edge diameter was measured by a sizing tube, and the cross-sectional graft area was calculated: (AM diameter/2)2 × 3.14 + (PL diameter/2)2 × 3.14. Statistical analysis was performed for the comparison of the cross-sectional area between the cadaveric ACL midsubstance and the ST double-bundle ACL autografts. The cadaveric midsubstance cross-sectional ACL area was 49.0 ± 16.3 mm2. The cross-sectional ST double-bundle autografts area was 52.8 ± 7.6 mm2. The ST double-bundle autograft area showed no significant difference when compared with the midsubstance cross-sectional ACL area. ST double-bundle autografts were shown to be capable of reproducing the midsubstance cross-sectional ACL area.
Establishing significance of gravitational-wave signals from a single observatory in the PyCBC offline search
Authors: Cabourn Davies Gareth S , Harry Ian W 
Published: August 2022

Abstract
Gravitational-wave observations of compact binary coalescences are allowing us to see black holes and neutron stars further into the Universe and recent results represent the most sensitive searches for compact objects ever undertaken. Most searches for gravitational waves from compact binary coalescence currently rely on detecting coincident triggers from multiple detectors. In this paper, we describe a new method for extrapolating significance of single-detector signals beyond the live-time of the analysis. Using this method, we can recover loud signals which only triggered in a single detector. We demonstrate this method in a search of O3 data, and recover seven single-detector events with a false alarm rate less than two per year. These were the same events as discovered in the GWTC-2.1 and GWTC-3 searches in a single detector, and all but one event from 3-OGC and 4-OGC. Through a campaign of injected signals, we estimate that the total time–volume sensitivity increases by a factor of up to 1.20 ± 0.02 at a false alarm rate of one per two years compared to completely ignoring single-detector events.
On the relation between asymptotic charges, the failure of peeling and late-time tails
Authors: Gajic Dejan , Kehrberger Leonhard M A 
Published: August 2022

Abstract
The last few years have seen considerable mathematical progress concerning the asymptotic structure of gravitational radiation in dynamical, astrophysical spacetimes. In this paper, we distil some of the key ideas from recent works and assemble them in a new way in order to make them more accessible to the wider general relativity community. In the process, we also discuss new physical findings. First, we introduce the conserved f(r)-modified Newman–Penrose charges on asymptotically flat spacetimes, and we show that these charges provide a dictionary that relates asymptotics of massless, general spin fields in different regions: asymptotic behaviour near i
+ (‘late-time tails’) can be read off from asymptotic behaviour towards

I

+

, and, similarly, asymptotic behaviour towards

I

+

can be read off from asymptotic behaviour near i
− or

I

−

. Using this dictionary, we then explain how: (I) the quadrupole approximation for a system of N infalling masses from i
− causes the ‘peeling property towards

I

+

’ to be violated, and (II) this failure of peeling results in deviations from the usual predictions for tails in the late-time behaviour of gravitational radiation: instead of the Price’s law rate

r

Ψ

[

4

]

|

I

+

∼

u

−
6

as u → ∞, we predict that

r

Ψ

[

4

]

|

I

+

∼

u

−
4

, with the coefficient of this latter decay rate being a multiple of the monopole and quadrupole moments of the matter distribution in the infinite past.
Sequential versus concurrent gradient-based optimal algorithms for the robust control of quantum systems
Authors: Dionis E , Sugny D 
Published: August 2022

Abstract
We investigate two different formulations of gradient-based algorithms for the robust control of quantum systems. We consider the simultaneous control of an ensemble of systems which differ by the value of a constant Hamiltonian parameter. The two versions of the iterative algorithm, called concurrent and sequential, correspond respectively to a joint update of the control at each iteration for all the elements of the ensemble or to a successive correction of the control in which the control law is different for each system. We analyze the relative efficiency of the two optimization procedures on two benchmark examples, namely the control of two-level quantum systems and Bose–Einstein condensates in a one-dimensional optical lattice. Intensive numerical simulations show the superiority of the sequential-update formulation with respect to the concurrent one for a similar numerical cost.
Laser-induced enhancement of vertical polarization in ferroelectric bilayer WTe2
Authors: Yang Qing , Song Chenchen , Meng Sheng 
Published: August 2022

Abstract
Light–matter interaction is one of the key means to manipulate the structural and electronic properties of materials, especially in two-dimensional (2D) layered materials, which are optically accessible due to their atomic thickness. We propose that an ultrashort laser pulse could drastically enhance the ferroelectric polarization of bilayer WTe2 by our real-time time-dependent density functional theory simulations. It is noted that bilayer WTe2 is a 2D sliding ferroelectric material recently discovered whose vertical polarization can be controlled by a slight horizontal displacement. We demonstrate that interlayer sliding and compression are simultaneously achieved upon illumination of linearly polarized near-infrared laser pulse, leading to an ultrafast electric polarization enhancement by ∼230% within hundreds of femtosecond. Two major contributions have been identified: (a) the piezoelectric effect due to laser-induced interlayer compression, caused by interlayer charge transfer and dipole-dipole interaction; (b) the interlayer sliding along the opposite direction of ferroelectric switching, induced by inhomogeneous excited carrier distribution and specific electron-phonon couplings. This work provides new insights on controlling ferroelectricity of layered materials, which may extend to other van der Waals bilayers and even bulk materials.
Nanoscale mapping of shifts in dark plasmon modes in sub 10 nm aluminum nanoantennas
Authors: Elibol Kenan , Downing Clive , Hobbs Richard G 
Published: August 2022

Abstract
In this work, we report the fabrication and spectroscopic characterization of subwavelength aluminum nanocavities—consisting of hexamer or tetramer clusters of sub 10 nm width Al nanorods—with tunable localized surface plasmon resonance (LSPR) energies on suspended SiN
x
membranes. Here the volume plasmon (VP) and LSPR modes of lithographically-fabricated Al nanocavities are revealed by low-loss electron energy-loss spectroscopy (EELS) in an aberration corrected scanning transmission electron microscope (STEM). We show that the existence of grain boundaries (GBs) in these nanocavities results in shifts in the VP energy and a reduction in the VP lifetime. We map the VP energy and lifetime across GBs and we observe a decrease in VP energy and lifetime at GBs that is consistent with a reduction in free carrier density and increased plasmon scattering at these locations. Dipolar LSPR modes resonant in the UV and blue regions of the electromagnetic spectrum as well as higher-energy optically dark quadrupolar and hexapolar LSPR modes are also observed and mapped by STEM and EELS. All LSPR modes are confirmed via electromagnetic simulations based on the boundary element method. Both tetramer and hexamer structures support the excitation of dipolar bright and dipolar dark modes. Finally, we find that asymmetries in fabricated nanorod hexamer and tetramer nanocavities result in a mode mixing leading to a shift in dipolar dark LSPR modes.
Measurement of the Newton’s cooling law time-constant by Arduino: an idea for STEM education in high schools
Authors: Casaburo Fausto 
Published: August 2022

Abstract
Commercial electronic measuring devices used in physics usually have high costs. In recent years, thanks to its low cost and the high number of available sensors, the Arduino board has been used for many educational purposes in physics education. In this paper a method to measure the Newton’s cooling law time-constant by the Arduino board is presented.
Applications of a patient-specific whole-body CT-mesh hybrid computational phantom in second cancer risk prediction
Authors: Kollitz Erika , Roew Moritz , Han Haegin , Pinto Marco , Kamp Florian , Kim Chan Hyeong , Schwarz Marco , Belka Claus , Newhauser Wayne , Parodi Katia , Dedes George 
Published: August 2022

Abstract

Objective. CT-mesh hybrid phantoms (or ‘hybrid(s)’) made from integrated patient CT data and mesh-type reference computational phantoms (MRCPs) can be beneficial for patient-specific whole-body dose evaluation, but this benefit has yet to be evaluated for second cancer risk prediction. The purpose of this study is to compare the hybrid’s ability to predict risk throughout the body with a patient-scaled MRCP against ground truth whole-body CTs (WBCTs). Approach. Head and neck active scanning proton treatment plans were created for and simulated on seven hybrids and the corresponding scaled MRCPs and WBCTs. Equivalent dose throughout the body was calculated and input into five second cancer risk models for both excess absolute and excess relative risk (EAR and ERR). The hybrid phantom was evaluated by comparing equivalent dose and risk predictions against the WBCT. Main results. The hybrid most frequently provides whole-body second cancer risk predictions which are closer to the ground truth when compared to a scaled MRCP alone. The performance of the hybrid relative to the scaled MRCP was consistent across ERR, EAR, and all risk models. For all in-field organs, where the hybrid shares the WBCT anatomy, the hybrid was better than or equal to the scaled MRCP for both equivalent dose and risk prediction. For out-of-field organs across all patients, the hybrid’s equivalent dose prediction was superior than the scaled MRCP in 48% of all comparisons, equivalent for 34%, and inferior for 18%. For risk assessment in the same organs, the hybrid’s prediction was superior than the scaled MRCP in 51.8% of all comparisons, equivalent in 28.6%, and inferior in 19.6%. Significance. Whole-body risk predictions from the CT-mesh hybrid have shown to be more accurate than those from a reference phantom alone. These hybrids could aid in risk-optimized treatment planning and individual risk assessment to minimize second cancer incidence.
Electron heating mode transition induced by the magnetic confinement of secondary electrons in capacitively coupled radio frequency discharges
Authors: Sun Jing-Yu , Wen Hui , Zhang Quan-Zhi , Schulze Julian , Liu Yong-Xin , Wang You-Nian 
Published: August 2022

Abstract
Based on particle-in-cell and test-particle simulations, an α- to γ-mode transition of the electron power absorption dynamics is found to be induced as a function of an externally applied transverse magnetic field in low pressure capacitively coupled radio frequency discharges operated in argon. This transition is caused by the increased magnetic confinement of energetic ion-induced secondary electrons (γ-electrons) at higher magnetic fields. If a transverse magnetic field is applied, γ-electrons, that are accelerated to high energies by the sheath electric field, are confined in the vicinity of the sheath. Due to their gyromotions they are returned periodically to the adjacent sheath and interact repetitively with the sheath electric field. Such confined γ-electrons are, thus, effectively multiplied by ionization collisions in the vicinity of the sheath, thereby resulting in a significant enhancement of the local ionization rate and the plasma density. In such cases, the energy coupling efficiency of γ-electrons is greatly enhanced, implying that the discharge operates in a magnetized γ-mode. Moreover, the effects of the magnetic field on ion properties and ionization dynamics at different driving frequencies and operating pressures are studied.
Parametric studies of stream instability-induced higher harmonics in plasma ionization breakdown near an emissive dielectric surface
Authors: Wen De-Qi , Zhang Peng , Krek Janez , Yangyang Fu , Verboncoeur John P 
Published: August 2022

Abstract
In this work, we comprehensively investigate the generation of higher harmonic (HH) electric fields normal to the applied rf electric field in multipactor-coexisting plasma breakdown by fully kinetic particle-in-cell (PIC) simulations and a theoretical model. Firstly, a base case at driving frequency 1 GHz, transverse rf electric field amplitude 3 MV m−1, and background gas pressure 0.2 Torr, is studied in detail. The enhanced harmonic frequency observed is around ten times the fundamental rf frequency, significantly lower than the Langmuir frequency. A theoretical model reveals that the fundamental mechanism of HHs generation is stream–plasma instability, which originates from stream-like secondary electron emission interacting with plasma. The resulting HH frequency and the growth rate of its oscillating amplitude from the theoretical model, agree well with the PIC simulations. With increasing pressure, the HH oscillations are found to be significantly reduced. This is because at higher pressure the gas ionization rate is higher, which causes a more rapidly increasing plasma density, leaving less time for the growth of instability. Furthermore, the parameter space in terms of background gas pressure and rf field amplitude within which the HHs appear is revealed. Finally, the effect of the driving rf frequency on HHs is also investigated, and it is found that the instability-induced oscillating HHs field remains when the driving frequency is increased to 2 GHz, however, it is highly reduced at higher driving frequency of 5 GHz, as oscillations at the fundamental frequency start playing a more important role.
Vibrational relaxation and triggering of the non-equilibrium vibrational decomposition of CO2 in gas discharges
Authors: Kotov Vladislav 
Published: August 2022

Abstract
Non-equilibrium vibrational dissociation CO2 → CO + O at translational–rotational temperatures T ⩽ 1200 K is investigated with semi-empiric and computational models. The governing parameter

Q
/

n

0

2

has been introduced, where Q is the specific volumetric power coupled into vibrational states and n
0 is the initial number density of CO2. It has been shown that the non-equilibrium vibrational process can only be triggered when

Q
/

n

0

2

exceeds some critical value determined by the speed of vibrational relaxation. Simple semi-empiric calculations are backed by the state-to-state simulations of the CO2 vibrational kinetics in two-modes approximation performed for conditions of microwave sustained gas discharges. The vibrational kinetics model is benchmarked against the experimental vibrational relaxation times as well as the shock tube data on the rate of the process CO2 + M → CO + O + M for M = Ar and literature data for M = CO2. At T = 300 K the estimated

Q
/

n

0

2

crit

≂
6
×
1

0

−
40

W m3 or

Q
/

p

2

crit

≂

35 W (m−
3 Pa−
2) (p is the gas pressure).

Q
/

p

2

crit

is found to always increase with increased T.
Effect of an electron beam on a dual-frequency capacitive rf plasma: experiment and simulation
*
Authors: Bogdanova M , Lopaev D , Zotovich A , Proshina O , Rakhimova T , Zyryanov S , Rakhimov A 
Published: August 2022

Abstract
One of the crucial challenges facing modern microelectronics is to provide plasma surface treatment at the single atomic level. To minimize defects in the underlying layers, these processes require ions with very low energies—lower than in conventional radio-frequency (rf) plasma and close to the binding energy of atoms. A conventional rf dual-frequency capacitively coupled plasma (df CCP) discharge with additional ionization by an electron beam is considered as a possible solution to this problem. This paper contains a study on the electron beam effect on 81 & 12 MHz plasma parameters such as electron energy probability function, plasma density, electron temperature and ion energy distribution at an rf-biased electrode. The experimental part of the study includes measurements carried out in an asymmetric rf df CCP discharge in Ar at 100 mTorr pressure using a Langmuir probe, a hairpin-probe, and a retarding field energy analyzer. The behavior of plasma parameters is considered in the different types of plasma: electron beam plasma, when no rf power is applied, as well as rf plasma with and without an electron beam. The 1D PIC MCC simulation is used to analyze the effect of an electron beam on the df rf plasma. The obtained results showed that the electron temperature and, accordingly, the energy of ions coming at the electrode surface can be lowered. The use of an electron beam in a df CCP discharge allows to control the plasma density, electron temperature and ion energy spectrum in the low-energy range, which can be of essential interest for atomic layer etching and atomic layer deposition technologies.
Reduced granularity in BHO-doped YBCO films on RABiTS templates
Authors: Holleis Sigrid , Shipulin Ilya A , Hühne Ruben , Bernardi Johannes , Eisterer Michael 
Published: August 2022

Abstract
REBCO based coated conductors (CCs) are a viable alternative to conventional superconductors for many applications, therefore the optimization of their current carrying capacity is an ongoing process. A promising route for the increase in performance is the introduction of artificial pinning centers such as BaHfO3 (BHO) nanoparticles. However, granularity still imposes a substantial performance limitation, especially in REBCO CCs deposited on RABiTS based templates, as the critical current density is severely reduced by moderate misalignment angles of adjacent grains. A combined study of scanning Hall probe microscopy and electron microscopy of undoped and BHO-doped YBa2Cu3O7-δ
(YBCO) films on technical templates shows that BHO-doping leads to a denser microstructure of the superconducting layer and higher global and local critical current densities. The statistical evaluation of local current maps allows for a quantification of the magnetic granularity where a reduction of granularity with increasing film thickness, doping and increasing temperature is found. In particular, the dependence of granularity on the film thickness and enhanced film growth through BHO-doping shows the potential for further optimization of YBCO films on RABiTS based templates.