bluuebunny/crossref_metadata_2025_split huggingface dataset:
The access‐equity dualism of online learning in community colleges
Authors: Sublett Cameron 
Published: March 2022

AbstractThe COVID‐19 pandemic led to an unprecedented adoption of online learning in community colleges. On one hand, online learning increases access and offers students flexibility and convenience. On the other hand, existing research illustrates online courses increase achievement and equity gaps. Hence, this article contends that online learning in community colleges, as practiced, represents an access‐equity dualism which the author argues is an extension of the contradictory college paradigm. In addition to detailing the access‐equity dualism of community college online learning, the goal of the article is to inform decision making among community college stakeholders interested in building the next generation of accessible and equitable community college online courses and programs.
NPS detection in prison: A systematic literature review of use, drug form, and analytical approaches
Authors: Vaccaro Giorgia , Massariol Anna , Guirguis Amira , Kirton Stewart B. , Stair Jacqueline L. 
Published: March 2022

AbstractThis paper presents a systematic literature review on the detection of new psychoactive substances (NPS) in prison settings. It includes the most frequently reported NPS classes, the routes and forms used for smuggling, and the methods employed to analyse biological and non‐biological samples. The search was carried out using MEDLINE (EBSCO), Scopus (ELSEVIER), PubMed (NCBI), and Web of Science (Clarivate) databases, along with reports from the grey literature in line with the PRISMA‐S guidelines. A total of 2708 records were identified, of which 50 met the inclusion criteria. Findings showed the most prevalent NPS class reported in prison was synthetic cannabinoids (SCs). The most frequently reported SCs in non‐biological samples were 4F‐MDMB‐BINACA, MDMB‐4en‐PINACA, and 5F‐ADB. These were smuggled mainly through the postal services deposited on paper or herbal matrices. Concentrations of SCs detected on seized paper ranged between 0.05 and 1.17 mg/cm2. The SCs most frequently reported in biological specimens (i.e., urine, blood, saliva, and wastewater) were 5F‐MDMB‐PICA, 4F‐MDMB‐BINACA, and MDMB‐4en‐PINACA. Concentrations of SCs reported in femoral blood and serum were 0.12–0.48 ng/ml and 34–17 ng/ml, respectively. Hyphenated techniques were predominantly employed and generally successful for the detection of NPS in biological (i.e., LC‐HRMS/MS) and non‐biological samples (i.e., LC‐HRMS/MS and GC–MS). The onsite technique IMS showed promise for detecting SCs in various forms; however, immunoassays were not recommended. Future work should focus on accurate in‐field detection of SCs deposited on paper and in urine and saliva to improve real‐time decision‐making, as well as wastewater and air monitoring for overall drug use trends.
Temperature and nutrient conditions modify the effects of phenological shifts in predator–prey communities
Authors: Rudolf V. H. W. 
Published: March 2022

AbstractAlthough there is mounting evidence indicating that the relative timing of predator and prey phenologies determines the outcome of trophic interactions, we still lack a comprehensive understanding of how the environmental context (e.g., abiotic conditions) influences this relationship. Environmental conditions not only frequently drive shifts in phenologies, but they can also affect the very same processes that mediate the effects of phenological shifts on species interactions. Therefore, identifying how environmental conditions shape the effects of phenological shifts is key to predicting community dynamics across a heterogeneous landscape and how they will change with ongoing climate change in the future. Here I tested how environmental conditions shape the effects of phenological shifts by experimentally manipulating temperature, nutrient availability, and relative phenologies in two predator–prey freshwater systems (mole salamander–bronze frog vs. dragonfly larvae–leopard frog). This allowed me to (1) isolate the effects of phenological shifts and different environmental conditions; (2) determine how they interact; and (3) evaluate how consistent these patterns are across different species and environments. I found that delaying prey arrival dramatically increased predation rates, but these effects were contingent on environmental conditions and the predator system. Although nutrient addition and warming both significantly enhanced the effect of arrival time, their effect was qualitatively different across systems: Nutrient addition enhanced the positive effect of early arrival in the dragonfly–leopard frog system, whereas warming enhanced the negative effect of arriving late in the salamander–bronze frog system. Predator responses varied qualitatively across predator–prey systems. Only in the system with a strong gape limitation were predators (salamanders) significantly affected by prey arrival time and this effect varied with environmental context. Correlations between predator and prey demographic rates suggest that this was driven by shifts in initial predator–prey size ratios and a positive feedback between size‐specific predation rates and predator growth rates. These results highlight the importance of accounting for temporal and spatial correlations of local environmental conditions and gape limitation when predicting the effects of phenological shifts and climate change on predator–prey systems.
The new HFA/ICOS risk assessment tool to identify patients with chronic myeloid leukaemia at high risk of cardiotoxicity
Authors: Di Lisi Daniela , Madaudo Cristina , Alagna Giulia , Santoro Marco , Rossetto Ludovico , Siragusa Sergio , Novo Giuseppina 
Published: March 2022

AbstractAimsTyrosine kinase inhibitors (TKIs) used to treat chronic myeloid leukaemia (CML) can cause cardiovascular adverse events. So far, the Systematic Coronary Risk Evaluation (SCORE) charts of the European Society of Cardiology (ESC) have been used to identify cancer patients at increased cardiovascular risk. The primary aim of our study was to evaluate the usefulness of the new cardiovascular risk assessment model proposed by the Cardio‐Oncology Study Group of the Heart Failure Association (HFA) of the ESC in collaboration with the International Cardio‐Oncology Society (ICOS) to stratify the cardiovascular risk in CML patients, compared with SCORE risk charts. The secondary aim was to establish the incidence of adverse arterial events (AEs) in patients with CML treated with TKIs and the influence of preventive treatment with aspirin.Methods and resultsA retrospective single‐centre observational study was carried out on 58 patients (32 men and 26 women; mean age ± SD: 59 ± 15 years) with CML treated with TKIs for a median period of 43 ± 31 months. Cardiological evaluation was performed and cardiovascular risk was estimated with SCORE risk charts and with the new risk assessment tool proposed by HFA/ICOS. AEs were recorded. According to SCORE charts and the new HFA/ICOS risk stratification tool, respectively, 46% (Group A1) and 60% (Group A2) of patients were at high–very high risk, and 54% (Group B1) and 40% (Group B2) at low–moderate risk. AEs were significantly more frequent in Group A1 than Group B1 (P value < 0.01) when considered overall; they were significantly more frequent in Group A2 than Group B2 either overall or considered individually. HFA/ICOS risk stratification tool was significantly more sensitive than SCORE (P < 0.01) in identifying patients at higher risk of cardiovascular toxicity. In addition, we did not find AEs in patients pretreated with aspirin.ConclusionsThe new HFA/ICOS risk stratification model allows a more tailored cardiovascular risk stratification in patients with CML and it is more sensitive than SCORE charts.
Grants and funding at mid‐career: Planning with purpose to achieve agency, vitality, and fulfillment
Authors: Pifer Meghan J. 
Published: March 2022

AbstractAcross disciplines, mid‐career faculty may be motivated by internal and external factors to pursue financial support for their work. Yet, it is unclear how mid‐career faculty navigate individualized realities to develop the necessary skills for success in this aspect of their careers. This chapter guides the reader through planning for the pursuit of funding at mid‐career in ways that promote agency, vitality, and fulfillment. Rather than emphasizing strategies for securing grants, it focuses on a reflective practice that places at the foreground individual decision‐making in alignment with personal goals, talents, and needed areas of development. The chapter includes an overview of challenges faced by mid‐career faculty as well as growth‐promoting models of academic careers, and then transitions to a reflective planning guide. It concludes with recommendations for key stakeholders in support of mid‐career faculty.
Sustainable. Purposeful. Thriving: Critical hope for mid‐career research and practice
Authors: Terosky Aimee LaPointe , Baker Vicki L. 
Published: March 2022

AbstractThis chapter synthesizes three themes that unite this book's chapters, including critical hope, agency within equitable contexts, and social capital. In addition to descriptions and examples of each theme, the chapter provides recommendations for future research and implications for practice to enhance the experiences of mid‐career faculty.
Descriptive analysis of recurrences of nasal intestinal‐type adenocarcinomas after radiotherapy
Authors: Abu‐Shama Yazan , Renard Sophie , Nguyen Duc Trung , Henrot Philippe , Toussaint Bruno , Rumeau Cécile , Gallet Patrice , Jankowski Roger 
Published: March 2022

AbstractBackgroundDespite adjuvant radiotherapy, rates of recurrences of endoscopically operated nasal intestinal‐type adenocarcinomas (ITAC) have not been improved in successive series. To better understand how to improve local control, we aimed to investigate the site of local recurrences of ITACs.MethodsRetrospective study in a reference center in sinonasal malignancies. For all patients with a local recurrence, radiotherapy plans were retrieved and compared to the delineation of local recurrences.ResultsOf 63 patients, 54 underwent adjuvant radiotherapy of which 14 (25.9%) had a local recurrence. Eleven of them had their onset in an optimally irradiated area. Difficulty to dissect the cribriform plate and/or the lateral lamina was reported for 11 patients with local recurrences in the operative reports (p <0.0001).ConclusionsMost of recurrences arose in an optimally irradiated area. A close cooperation between surgeons and radiotherapists is required to define areas at risk and adapt treatment.
Interpersonal communication may improve equity in dementia risk education
Authors: Fair Hannah , Klekociuk Shannon , Eccleston Claire , Doherty Kathleen , Farrow Maree 
Published: March 2022

AbstractIssue addressedEncouraging people to adopt life‐long habits that reduce dementia risk is necessary to manage the growing global prevalence of this condition and is, therefore, a global health priority. Current initiatives promoting risk‐reducing behaviour primarily attract participants from a limited range of backgrounds, even if widely available. This may inadvertently increase health inequities, as the people who are most likely to develop dementia are the people who are least involved in risk‐reduction initiatives. Interpersonal communication can effectively disseminate health messages to demographically diverse populations and may, therefore, broaden the reach of dementia risk‐reduction information.MethodsCoding reliability thematic analysis was used to categorise reports of information sharing provided by participants from one global online dementia risk education initiative, the Preventing Dementia Massive Open Online Course, or MOOC. These reports of information sharing were provided in response to the feedback question: “If you have already applied your MOOC learning, please tell us how.”ResultsInformation was reportedly shared with a wide range of people, including those from demographic groups that are under‐represented among Preventing Dementia MOOC participants. Information about specific risk factors was shared, along with general information about the course and/or dementia risk reduction. Some participants also reported that the people they shared information with were initiating risk‐reducing behaviours.ConclusionInterpersonal communication has the potential to disseminate dementia risk reduction information to, and promote behaviour change among, a broad group of people at risk of dementia, thereby increasing equity in dementia risk education.
A multiple hydrograph separation technique for identifying hydrological model structures and an interpretation of dominant process controls on flow duration curves
Authors: Leong Chris , Yokoo Yoshiyuki 
Published: March 2022

AbstractThere has been significant progress made towards understanding the process controls that govern the shapes of flow duration curves (FDC). However, the transferability of the knowledge gained to large spatial scales is still lacking, partly due to the fixed representation of the model structures representing the unobserved underground layer. In the context of improving large scale applicability/transferability of FDC studies: (1) we propose a novel approach to transform/restructure the representation of the subsurface component in hydrological models to be flexible and adaptable in any environment and (2) provide a thorough interpretation of the dominant processes that impact the shape of FDCs. The flexible structure is designed from a series of multiple connected linear reservoirs that are developed from a unique multiple hydrograph separation procedure, to estimate the number of distinct hydrological processes at play. The main results are: (1) wet catchments have more complex model structures (more reservoirs) than arid catchments; indicating that subsurface processes are potentially more present in wet catchments than in drier ones. Dry catchments have more near surface occurring processes, thus have less complex model structures. However, more complexity is potentially required within the internal reservoirs of dry catchments. (2) The strength of interference in the intermediate reservoirs in controlling the dominant processes towards the bottom determined the shape of FDCs, and this increased with aridity. The novel finding is that a model structure can be determined by the catchment's ability to generate flows as well as the strength of low flow persistence. Hence, we propose a conceptual framework for the development of flexible model structures based on the shapes of FDCs. The transformation of models to be flexible in this research, should contribute to studies that seek the transferability of models over large spatial scales.
Longitudinal association between poor parental supervision and risk‐taking behavior: The role of self‐control and school climate
Authors: Dou Kai , Wang Lin‐Xin , Cheng Dan‐Li , Li Yan‐Yu , Zhang Ming‐Chen 
Published: March 2022

AbstractIntroductionAlthough poor parental supervision has been associated with an increased adolescents' propensity for risk‐taking behavior, few researchers have investigated nuanced mechanisms ofhowandfor whomfrom the perspective of “family × school.” Inspired by ecological system theory and self‐control theory, this study aimed to investigate the mediating role of self‐control and the moderating role of school climate between the link between poor parental supervision and risk‐taking behavior.MethodsFour hundred and ninety‐one Chinese adolescents (231 females,Mage = 15.39 ± 1.36) were recruited to participate in a three‐wave longitudinal study (3 months apart) and complete questionnaires regarding poor parental supervision (W1), school climate (W1), self‐control (W2), and risk‐taking behavior (W1/W3).ResultsAfter controlling for W1 risk‐taking behavior, our moderated mediation model indicated that W1 poor parental supervision was positively related to W3 risk‐taking behavior by restraining the development of W2 self‐control. Additionally, a high level of school climate as a protective factor buffered the negative impact of poor parental supervision on adolescents' self‐control, further reducing risk‐taking behavior.ConclusionOur findings shed light on the processing mechanisms between poor parental supervision and risk‐taking behavior among Chinese adolescents and underscore the importance of effective preventions and interventions to facilitate adolescents' healthy development.
Imaging approaches for monitoring three‐dimensional cell and tissue culture systems
Authors: Hilzenrat Geva , Gill Emma T. , McArthur Sally L. 
Published: March 2022

AbstractThe past decade has seen an increasing demand for more complex, reproducible and physiologically relevant tissue cultures that can mimic the structural and biological features of living tissues. Monitoring the viability, development and responses of such tissues in real‐time are challenging due to the complexities of cell culture physical characteristics and the environments in which these cultures need to be maintained in. Significant developments in optics, such as optical manipulation, improved detection and data analysis, have made optical imaging a preferred choice for many three‐dimensional (3D) cell culture monitoring applications. The aim of this review is to discuss the challenges associated with imaging and monitoring 3D tissues and cell culture, and highlight topical label‐free imaging tools that enable bioengineers and biophysicists to non‐invasively characterise engineered living tissues.
High performance of Co3O4@carbon composites as anodes for Lithium‐ion batteries
Authors: Xie Huan , Yang Guang , Cai Zhenyu , Li Ze , Wang Yinwei 
Published: March 2022

AbstractBACKGROUNDMetal oxides suffer from huge volume changes and poor electrical conductivity as anode materials in lithium‐ion batteries. Many nanostructures have been designed to improve the electrochemical performance of metal oxide anodes.RESULTSIn this work, Co3O4@carbon composites are prepared via hydrothermal reaction. The as‐prepared Co3O4@carbon composites displayed good lithium storage performance and excellent cycling stability. The Co3O4@carbon anode showed a high capacity of 986 mAh/g after 100 cycles at 0.2 C.CONCLUSIONThe superior electrochemical performance of the Co3O4@carbon anode is attributed to its unique hybrid structure, which can improve electrical conductivity and act as a buffer for the volume change during electrochemical reactions. © 2022 Society of Chemical Industry (SCI).
Synthesis of ceramic tubular membrane from low‐cost clay precursors for blood purification application as substitute of commercial dialysis membrane
Authors: Roshni M , Pugazhenthi G. , Periyasamy R. , Vasanth D. 
Published: March 2022

AbstractBackgroundThere has been a surge of interest in the preparation of membranes for clinical applications, chiefly for hemodialysis and hemofiltration. Despite numerous benefits, the exploitation of polymeric materials for dialysis membrane preparation remains unsatisfactory due to lack of proper physicochemical properties and biocompatibility. Therefore, this work focuses on the preparation of a ceramic membrane in a tubular configuration using an extrusion method and a clay material mixture. The biocompatibility of the membrane as well as its structural properties were studied.ResultsThe porosity, permeability and pore size of the membrane were 39 ± 0.88%, 203 ± 0.51 L m−2 h−1 bar−1 and 304 ± 1.20 nm, respectively. The corrosion tolerance of the membrane was found to be better in acidic, alkaline and chlorine solutions. The protein adsorption, hemolysis and platelet adhesion were 2.1 ± 0.03 μg cm−2, 1.02 ± 0.01% and 6856 ± 84 platelets mm−2, respectively. The membrane demonstrated a prolonged blood coagulation time (PT = 18 ± 0.33 s and APTT = 70 ± 0.57 s), a 171 ± 0.57 s whole blood clotting time and complement activation of 805 ± 1.3 mg L−1 for C3 and 247.3 ± 0.98 mg L−1 for C4. During synthetic blood filtration, the membrane had sieving coefficients of 0.98 ± 0.005, 0.97 ± 0.008 and 0.93 ± 0.005 for creatinine, urea and phosphate, respectively. Finally, the membrane revealed a protein rejection of about 56 ± 0.57%.ConclusionsThe overall findings indicated that the prepared tubular membrane with excellent biocompatibility and uremic toxin removal can be used for hemofiltration application as an alternative to hemodialysis. © 2022 Society of Chemical Industry (SCI).
Postauthorization safety study of betaine anhydrous
Authors: Mütze Ulrike , Gleich Florian , Garbade Sven F. , Plisson Céline , Aldámiz‐Echevarría Luis , Arrieta Francisco , Ballhausen Diana , Zielonka Matthias , Petković Ramadža Danijela , Baumgartner Matthias R. , Cano Aline , García Jiménez María Concepción , Dionisi‐Vici Carlo , Ješina Pavel , Blom Henk J. , Couce Maria Luz , Meavilla Olivas Silvia , Mention Karine , Mochel Fanny , Morris Andrew A. M. , Mundy Helen , Redonnet‐Vernhet Isabelle , Santra Saikat , Schiff Manuel , Servais Aude , Vitoria Isidro , Huemer Martina , Kožich Viktor , Kölker Stefan 
Published: March 2022

AbstractPatient registries for rare diseases enable systematic data collection and can also be used to facilitate postauthorization safety studies (PASS) for orphan drugs. This study evaluates the PASS for betaine anhydrous (Cystadane), conducted as public private partnership (PPP) between the European network and registry for homocystinurias and methylation defects and the marketing authorization holder (MAH). Data were prospectively collected, 2013–2016, in a noninterventional, international, multicenter, registry study. Putative adverse and severe adverse events were reported to the MAH's pharmacovigilance. In total, 130 individuals with vitamin B6 nonresponsive (N = 54) and partially responsive (N = 7) cystathionine beta‐synthase (CBS) deficiency, as well as 5,10‐methylenetetrahydrofolate reductase (MTHFR; N = 21) deficiency and cobalamin C (N = 48) disease were included. Median (range) duration of treatment with betaine anhydrous was 6.8 (0–9.8) years. The prescribed betaine dose exceeded the recommended maximum (6 g/day) in 49% of individuals older than 10 years because of continued dose adaptation to weight; however, with disease‐specific differences (minimum: 31% in B6 nonresponsive CBS deficiency, maximum: 67% in MTHFR deficiency). Despite dose escalation no new or potential risk was identified. Combined disease‐specific treatment decreased mean ± SD total plasma homocysteine concentrations from 203 ± 116 to 81 ± 51 μmol/L (p < 0.0001), except in MTHFR deficiency. Recommendations for betaine anhydrous dosage were revised for individuals ≥ 10 years. PPPs between MAH and international scientific consortia can be considered a reliable model for implementing a PASS, reutilizing well‐established structures and avoiding data duplication and fragmentation.
Effectively working with immigrants: A model for school counselors
Authors: Dogan Sabri 
Published: March 2022

AbstractThe purpose of this grounded theory study was to explore school counselors’ experiences working with immigrants. Based on this exploration, the author proposes a model that explains the process of becoming effective school counselors in working with immigrants. This model relies on social justice, and it consists of four developmental stages: superficial awareness, growing awareness, application, and culturally competent school counselor. Implications for school counselors are provided.