bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infant Tracheostomy: A 10-year experience in A Tertiary Centre
Authors: Ahmad Kailani Abdul Azim Al-Abrar , Aziz Azliana , Ab Hamid Suzina sheikh , Ramli Noraida 
Published: August 2022

We aim to report our experience of infant tracheostomies in a period of 10 years and discuss the indications, complications, outcome, and follow-up. This case series will contribute to the data of shifting trends in paediatric tracheostomy indications and outcomes. This study aims to review the indications, complications, and outcomes for paediatric tracheostomy at Hospital USM. A retrospective evaluation of the last ten years of experience at Hospital USM for all infants under the age of one who undergoes tracheostomy from January 2011 to January 2021 was undertaken. During the research period, twelve tracheostomies were performed. Complete data were available for all patients. There were 8 (67%) males and 4 (33%) females. The patient's age at the time of tracheostomy ranged from one day to nine months, with the mean age of tracheostomy insertion being 95 days. The most frequent indication was prolonged ventilation (50%), followed by upper airway obstruction caused by a craniofacial anomaly (33%), subglottic stenosis (8%), and laryngomalacia (8%). Sixteen per cent of patients were successfully decannulated. In newborns, tracheostomy is a life-saving procedure with high morbidity and mortality. The role of tracheostomy in airway management has evolved, both in terms of indication and outcome. This series complemented the current trends in indications of infant tracheostomy.
Pengaruh Kepemimpinan Dan Motivasi Terhadap Kinerja Pegawai Bagian Pengadaan Barang Dan Jasa Pemerintahan Kota Makassar
Authors: Andardinata Ady 
Published: August 2022

Pengaruh Kepemimpinan dan Motivasi terhadap Kinerja Pegawai Bagian Pengadaan Barang dan Jasa Pemerintahan Kota Makassa.Penelitian ini bertujuan untuk mengetahui pengaruh kepemimpinan dan motivasi terhadap kinerja pegawai bagian pengadaan barang dan jasa pemerintahan kota makassar. Jenis data yang digunakan dalam penelitian ini adalah data kualitatif dan data kuantitatif. Metode analisis data yang digunakan adalah dan analisis linear berganda yang hasilnya Y=0,800 + 0,499X1 + 0,487X2 ,koefisien determinasi yang hasilnya Adjusted R Square 0,450 atau 45,0%, dan korelasi (r) sebesar 0,671 atau 67,1% yang berarti dalam kriteria kuat. Hasil perhitungan regresi berganda diperoleh nilai F-hitung lebih besar dari pada F-tabel (13,076 > 3,28) pada taraf nyata 5%. Selanjutnya, hasil uji-t terhadap variabel kepemimpinan diperoleh nilai t-hitung lebih besar dari t-tabel (3,253 > 1,69389). Sementara variabel motivasi menghasilkan nilai t-hitung lebih besar dari t-tabel (2,454 > 1,69389) sehingga terdapat pengaruh signifikan antara variabel kepemimpinan maupun motivasi terhadap kinerja pegawai. oleh karena itu hipotesis yang diajukan dalam penelitian ini diterima.
DANÇAS NEGRAS EM AFRODIÁSPORAS
Authors: Zenicola Denise Mancebo 
Published: August 2022

O artigo propõe aprofundar o estudo de estética pós-colonial da Dança Afro-Brasileira Contemporânea. O objetivo é aumentar o entendimento de como criações coreográficas podem refletir fazeres corpóreos e performances que têm como marca um dançar em constante e elevado nível de reformulação cultural. Logo, procuramos analisar processos e escolhas de performances ocorridas nas memórias do corpo. Nosso eixo de análise temática utiliza alguns princípios teóricos de diásporas do corpo em Gilroy e do surgimento de novas formas culturais do multiculturalismo em Bhabha. Pretendemos, assim, refletir conceitos e processos de criadores de dança que manifestam, em um nível mais profundo, a confirmação de nossas potências culturais, identidades e diferenças em danças de diásporas, as chamadas Dança Afrocontemporânea ou Dança Afrodiaspórica.
Layer‐wise contribution‐filtered propagation for deep learning‐based fault isolation
Authors: Pan Zhuofu , Wang Yalin , Wang Kai , Ran Guangtao , Chen Hongtian , Gui Weihua 
Published: August 2022

AbstractDeep learning is gradually mainstreaming into data‐driven methods, relying on the advantages of extracting complicated nonlinear features. However, the black‐box property makes its decision rules non‐transparent, resulting in difficulty in attribution tasks, which aim to backtrack the contribution of network inputs to the outputs. Fault isolation and localization are techniques for diagnosing the root cause of system failures, which have a consistent objective with attribution for a deep learning‐based fault observer or classifier. Unfortunately, most fault isolation methods are based on shallow learning methods. Also, many attribution algorithms are linear without considering the influence of nonlinear activation functions. The related concerns motivate us to propose a new approach, namely layer‐wise contribution‐filtered propagation (LCP), for deep learning‐based fault isolation. In LCP, reasonable contributions are defined based on the influence of each layer input on maximizing the absolute output activation. A symbolic function is designed to identify neurons with negative contributions, which are then filtered and forbidden to backpropagate to the previous layer. By guiding correct attribution, LCP is available for any nonlinear activation functions and their combinations. It also provides a solution for fault isolation with stacked sample inputs, in which one single variable has several attributions associated with different times. Finally, two chemical simulations verify the effectiveness of the proposed method.
Dependency of Mesoscale Organization on Grid Anisotropy in Large‐Eddy Simulations of Convective Boundary Layers at Gray Zone Resolutions
Authors: de Roode Stephan R. , Siebesma A. Pier , Jansson Fredrik , Janssens Martin 
Published: August 2022

AbstractA new generation of operational atmospheric models operating at horizontal resolutions in the range 200 m ∼ 2 km is becoming increasingly popular for operational use in numerical weather prediction and climate applications. Such grid spacings are becoming sufficiently fine to resolve a fraction of the turbulent transports. Here we analyze Large‐eddy simulation results of a convective boundary layer obtained by coarsening horizontal grid spacings up to 800 m. The aim is to explore the dependency of the mean state and turbulent fluxes on the grid resolution. Both isotropic and anisotropic eddy diffusion approaches are evaluated, where in the latter case the horizontal and vertical eddy diffusivities differ in accord with their horizontal and vertical grid spacings. For coarsening horizontal grid sizes entrainment at the top of the boundary layer tends to get slightly enhanced for isotropic diffusion, whereas for the anisotropic diffusion approach the vertically well‐mixed boundary‐layer structure becomes severely degraded. An analysis of the energy spectrum shows that anisotropic diffusion causes relatively more dissipation of variance at smaller length scales. This leads, in turn, to a shift of spectral energy toward larger length scales that also becomes apparent from a rather different kind of spatial organization of convection. The present study therefore suggests that details with regards to the representation of processes at small scales might impact the organization at length scales much larger than the smallest scales that can be resolved by the model.
Deep polygenic neural network for predicting and identifying yield-associated genes in Indonesian rice accessions
Authors: Dominic Nicholas , Cenggoro Tjeng Wawan , Budiarto Arif , Pardamean Bens 
Published: August 2022

AbstractAs the fourth most populous country in the world, Indonesia must increase the annual rice production rate to achieve national food security by 2050. One possible solution comes from the nanoscopic level: a genetic variant called Single Nucleotide Polymorphism (SNP), which can express significant yield-associated genes. The prior benchmark of this study utilized a statistical genetics model where no SNP position information and attention mechanism were involved. Hence, we developed a novel deep polygenic neural network, named the NucleoNet model, to address these obstacles. The NucleoNets were constructed with the combination of prominent components that include positional SNP encoding, the context vector, wide models, Elastic Net, and Shannon’s entropy loss. This polygenic modeling obtained up to 2.779 of Mean Squared Error (MSE) with 47.156% of Symmetric Mean Absolute Percentage Error (SMAPE), while revealing 15 new important SNPs. Furthermore, the NucleoNets reduced the MSE score up to 32.28% compared to the Ordinary Least Squares (OLS) model. Through the ablation study, we learned that the combination of Xavier distribution for weights initialization and Normal distribution for biases initialization sparked more various important SNPs throughout 12 chromosomes. Our findings confirmed that the NucleoNet model was successfully outperformed the OLS model and identified important SNPs to Indonesian rice yields.
Long-Term Stability of Femtosecond Astigmatic Keratotomy After Treatment of High Postkeratoplasty Astigmatism
Authors: Mimouni Michael , Kisilevsky Eli , Alshaker Sara , Cohen Eyal , Trinh Tanya , Gouvea Larissa , Din Nizar , Chan Clara C. , Slomovic Allan R. , Rootman David S. , Sorkin Nir 
Published: August 2022

Purpose:
The purpose of this study was to assess long-term stability and outcomes of femtosecond astigmatic keratotomy (FSAK) after treatment of high postkeratoplasty astigmatism.

Methods:
This retrospective study included patients who underwent FSAK for high astigmatism (≥4 D) after penetrating keratoplasty or deep anterior lamellar keratoplasty. Main outcome measures were corneal astigmatism, uncorrected visual acuity, and best-corrected visual acuity (BCVA) at 1 month and 1, 5, and 10 years.

Results:
Overall, 61 eyes of 61 patients (mean age 56 ± 19 years, 54.1% male) were included in this study. Preoperative corneal astigmatism ranged from 4 to 25 D. One month after FSAK, mean corneal astigmatism was significantly reduced from 9.02 ± 3.97 D to 4.86 ± 3.10 D (P < 0.001). Thereafter, corneal astigmatism remained stable at all visits up to 10 years (P < 0.05 for all compared with baseline). After FSAK, there was a significant improvement in logMAR uncorrected visual acuity from 1.21 ± 0.48 to 0.87 ±0.54 (P < 0.001) and logMAR BCVA from 1.03 ± 0.55 to 0.49 ± 0.45 (P < 0.001) which remained stable up to 10 years. A mild reduction in BCVA improvement was seen between 1 month and 1 year.

Conclusions:
Femtosecond astigmatic keratotomy was effective and stable at reducing very high magnitudes of postkeratoplasty astigmatism over the long term. The procedure also had a stable effect on visual acuity, albeit some reduction in the degree of BCVA improvement was seen over the early postoperative period.
The Impact of Dedicated Research Years During Residency Upon Continued Academic Productivity of Plastic Surgeons
Authors: Reddy Narainsai K. , Applebaum Sarah A. , Gosain Arun K. 
Published: August 2022

Background:
This study explored the impact of dedicated research year(s) on long-term research productivity and career choices of plastic surgeons as academicians.

Methods:
Scopus and Web of Science were accessed in September 2020 to collate publications and H indexes of alumni who graduated from integrated plastic surgery residency programs from 2011 to 2020. Public profiles were utilized to determine academic status. Corresponding data were grouped by residency program type (traditional programs without required research, programs with one required research year, and a single program with variable research years). Unpaired t tests and 1-way analysis of variance were conducted to compare average H indexes and publication counts of alumni from each group. χ2 tests analyzed differences in academic statuses.

Results:
Alumni who completed one required research year published significantly more with a higher H index compared with those from traditional programs. Similar results were found among alumni who completed 2 research years compared with 0 or 1 year within a single program. Residents who completed one required research year were more likely to hold dual academic and nonacademic positions after graduation compared with their traditional counterparts. However, there was no statistical difference in academic status observed for surgeons who graduated from the program with variable research years.

Conclusions:
Participating in research year(s) during residency is predictive of ongoing academic productivity of surgeons within the first 10 years of completion of residency. This becomes important for training craniofacial surgeons, the majority of whom practice in academic settings.
RBP45d is required for 5’splice site selection via binding to intronic U-rich elements and interaction with PRP39a inArabidopsis thaliana
Authors: Huang Weihua , Zhang Liqun , Zhu Yajuan , Chen Jingli , Zhu Yawen , Lin Fengru , Huang Jirong 
Published: August 2022

AbstractA large number of cryptic splice sites in eukaryotic genome are generally dormant unless activated by mutations of authentic splice sites or splicing factors. How cryptic splice sites are used remains unknown in plants. Here, we identified two cryptic splicing regulators, RBP45d and PRP39a that are homologs of yeast U1 auxiliary protein Nam8 and Prp39, respectively, via genetic screening for suppressors of the virescentsot5mutant, which results from a point mutation at the 5’ splice site (5’ ss) of intron 7. PCR and DNA sequencing data showed that loss-of-function mutations inRBP45dandPRP39asignificantly increase the level of a cryptically spliced mRNA that encodes a mutated but partially functional sot5 protein, rescuingsot5to the WT phenotype. Yeast two hybrid and bimolecular fluorescence complementation assays demonstrated that RBP45d and PRP39a interact each other and also with the U1C, a core subunit of U1 small nuclear ribonucleoprotein (U1 snRNP). RNA electronic mobility shift assay showed that RBP45d directly binds to the uridine (U)-rich RNA sequence downstream of the cryptic 5’ ss. Consistently, our transcriptomic analysis revealed that a set of introns with U-rich sequences are retained inrbp45d. However, we found that other RBP45/47 members do not function redundantly with RBP45d, at least in regulation of cryptic splicing. Collectively, our data suggest that RBP45d is required for 5’ ss selection via binding to intronic U-rich elements and PRP39a in plants.One sentence summaryThe Arabidopsis RBP45d interacting with U1C and PRP39a is required for 5’ ss selection via binding to intronic U-rich elements.
Single‐element Anomaly Mapping from Stream Sediment Geochemical Landscapes Aided by Digital Terrain Analysis
Authors: XIANG Jie , XIA Peng , XIAO Keyan , CARRANZA Emmanuel John M. , CHEN Jianping 
Published: August 2022

AbstractThe identification of anomalies within stream sediment geochemical data is one of the fastest developing areas in mineral exploration. The various means used to achieve this objective make use of either continuous or discrete field models of stream sediment geochemical data. To map anomalies in a discrete field model of such data, two corrections are required: background correction and downstream dilution correction. Topography and geomorphology are important factors in variations of element content in stream sediments. However, few studies have considered, through the use of digital terrain analysis, the influence of geomorphic features in downstream dilution correction of stream sediment geochemical data. This study proposes and demonstrates an improvement to the traditional downstream dilution correction equation, based on the use of digital terrain analysis to map single‐element anomalies in stream sediment geochemical landscapes. Moreover, this study compares the results of analyses using discrete and continuous field models of stream sediment geochemical data from the Xincang area, Tibet. The efficiency of the proposed methodology was validated against known mineral occurrences. The results indicate that catchment‐based analysis outperforms interpolation‐based analysis of stream sediment geochemical data for anomaly mapping. Meanwhile, the proposed modified downstream dilution correction equation proved more effective than the original equation. However, further testing of this modified downstream dilution correction is needed in other areas, in order to investigate its efficiency further.
Barriers and facilitators in providing care for patients with a migration background
Authors: Claeys Ann , Berdai‐Chaouni Saloua , Tricas‐Sauras Sandra , De Donder Liesbeth 
Published: August 2022

AbstractAims and objectivesThe aim of this study was to identify the barriers and facilitators experienced by healthcare professionals while caring for patients with a migration background.BackgroundPeople with a migration background often face several structural inequalities and barriers in terms of accessibility to, and affordability of, healthcare. In order to provide quality care for patients with a migration background, it is important to understand which barriers healthcare professionals experience that prevent them from providing care and which factors can facilitate this.Design and methodsQualitative research following the COREQ criteria. A total of six focus groups (n = 37) and 12 individual interviews were conducted with a multidisciplinary sample: doctors, nurses, social workers, and occupational therapists. Nursing and medical students were also included. Thematic content analysis was used.ResultsKey findings suggest that the main barrier is that healthcare professionals regard people with a migration background as “the other”. Healthcare professionals do not feel secure or competent to provide care for these “others.” According to the healthcare professionals, the hospital structures—and, particularly, the managerial instances—appear to be only slightly supportive. Structural barriers at the level of the healthcare system, such as limited implementation of care coordination and austerity measures (time pressure or economic restrictions), were also perceived as barriers. Facilitators can be the healthcare professionals' attitude or the flexibility of the management.ConclusionsHealthcare professionals experience barriers in caring for people with a migration background. Othering plays a key role in building or maintaining several barriers. A multilevel approach is necessary to tackle these barriers and enable facilitators.Relevance to clinical practiceRaising awareness about “othering” in the educational programs of students and healthcare professionals is essential. Also, deploying support mechanisms and valuing the competences of multicultural and multi‐lingual healthcare professionals can help facilitate quality care for patients with a migrant background.Patient or Public ContributionPatients, informal and formal caregivers participated in the study at several stages (e.g.: by involving them during the research design phase or providing feedback and input at specific moments across the study). In addition, community participants played a key role also during the research design and data analysis phases as well as by facilitating patients' recruitment.
Outcomes of a Mini External Fixator System for the Treatment of Unstable Periphyseal Hand Fractures
Authors: GERMANO Silvia , CAVALIERI Enrico , PATANÈ Luca , CLEMENTE Alessandra , MERLINO Giorgio , BORSETTI Marco 
Published: August 2022

Background: Most unstable hand fractures in children are treated by closed methods. If osteosynthesis is required, Kirschner (K)-wires are commonly used, though they carry a risk of injury to the physis. We have been using a mini external fixator system (MEFS) for the treatment of unstable periphyseal fractures of the hand. The aim of this study is to describe the application and report the outcomes of MEFS for the treatment of periphyseal fractures of the hand.Methods: We retrospectively reviewed all the patients with periphyseal fracture of the hand treated with MEFS from March 2010 to December 2019. Data with regard to age, sex, hand dominance, digit and bone injured, mechanism of injury, medical records and related radiographs were collected. Salter–Harris classification was used to classify epiphyseal fractures and the Al-Qattan classification for categorising neck fractures. Range of motion and residual deformity of the affected fingers were evaluated during follow-up and at 3 months postoperatively.Results: Fourteen periphyseal unstable fractures were treated using closed reduction and MEFS. Only one patient with a fracture of the neck of the proximal phalanx of the little finger required revision surgery. No patient had pin site infection or pin loosening and the device was well tolerated by all patients. All fractures united and all the patients recovered a full range of motion at final follow-up.Conclusions: The MEFS is a reasonable alternative for unstable periphyseal fractures with good outcomes and avoids the risk of iatrogenic physeal injury from K-wire fixation.Level of Evidence: Level IV (Therapeutic)
Prognostic value of neutrophils to lymphocytes and platelets ratio for 28-day mortality in patients with acute respiratory distress syndrome: a retrospective study
Authors: Nie Shiyu , Wang Hongjin , Liu Qiuyu , Tang Ze , Tao Wu , Wang Nian 
Published: August 2022

Abstract
Background
Acute respiratory distress syndrome (ARDS) is a rapidly progressive and fatal respiratory failure disease that often occurs in critically ill patients. Since ARDS is associated with immune dysregulation and coagulation abnormalities, it is necessary to identify an appropriate predictor that can accurately predict ARDS mortality based on its pathophysiology. Therefore, this study aimed to evaluate the clinical value of neutrophils to lymphocytes and platelets ratio (N/LPR) in predicting 28-day mortality in ARDS patients.

Methods
From July 2018 to October 2021, the medical records of ARDS patients were retrospective reviewed. Neutrophil count, lymphocyte count, and platelet count were collected, and the neutrophil-to-lymphocyte ratio (NLR) and N/LPR were calculated. Multivariate logistic regression analyses were performed to identify independent predictors of 28-day mortality in ARDS. Receiver operating characteristic (ROC) curve with the area under curve (AUC) was used to evaluate optimal cut-off values for 28-day mortality in ARDS. Kaplan–Meier analysis was used to estimate the 28-day survival probabilities stratified by optimal cut-off values of N/LPR and NLR.

Results
A total of 136 ARDS patients were included in this study and were further divided into survivors (n = 69) and non-survivors (n = 67) groups according to their survival status on day 28. There were no significant differences between the two groups in age, sex, history of smoking and drinking, comorbidities, and reasons of admission (P > 0.05). Non-survivors had significantly higher neutrophil counts, NLR and N/LPR and had significantly lower platelet counts than survivors (P < 0.05). Multivariate regression analysis revealed that N/LPR, NLR and platelet counts were independent predictors for 28-day mortality in ARDS (P < 0.05). The ROC analyses showed that N/LPR with optimal cut-off value of 10.57 (sensitivity: 74.6%; specificity: 72.5%) is a more reliable predictor for 28-day mortality in ARDS than NLR and platelet count (AUC: 0.785 vs. 0.679 vs. 0.326). Further subgroup analysis confirmed that ARDS patients with N/LPR < 10.57 had significantly lower 28-day mortality than patients with N/LPR ≥ 10.57 (P < 0.001). Kaplan–Meier analysis also confirmed that ARDS patients with N/LPR < 10.57 had significantly longer survival.

Conclusion
N/LPR is an independent risk factor associated with 28-day mortality in ARDS patients and shows better performance in predicting mortality rate than NLR.