bluuebunny/crossref_metadata_2025_split huggingface dataset:
Targeted Implementation of HIV Self-Testing Increases Testing Uptake Among Partners of Index Persons Known to Have HIV in Kenya
Authors: Zewdie Kidist , Kiptinness Catherine , Ngure Kenneth , Kipkurui Nicholas , Wairimu Njeri , Ambiyo Faith , Mugo Nelly R. , Baeten Jared M. , Mugwanya Kenneth K. 
Published: April 2022

Background:
Partners of persons living with HIV (PLHIV) are at a high risk of HIV acquisition, particularly if PLHIV are newly diagnosed or not virally suppressed. A focused partner HIV testing strategy could stimulate efficient identification of persons for pre-exposure prophylaxis (PrEP) or antiretroviral therapy (ART) programs.

Methods:
We sequentially implemented 2 partner testing strategies at 2 Kenyan HIV clinics: (1) an invitation for clinic-based testing and (2) HIV self-testing (HIVST) kits distribution to index PLHIV. For each testing strategy, we enrolled approximately 150 consecutive index PLHIV with partners of unknown HIV status, not on ART, <6 months on ART, or who had detectable viral load. We compared partner engagement, testing uptake, and linkage for ART or PrEP between the 2 testing strategies.

Results:
Of 313 index PLHIV enrolled (160 in invitation, 153 in HIVST), the median age was 32 years (interquartile range 26–40) and 76% were women. Overall, 73% of participants (229) discussed HIV testing with their partners: 76% (121) in the invitation strategy vs 71% (108) in the HIVST strategy [adjusted odds ratio (adjOR): 0.54, 95% confidence interval (CI): 0.31 to 0.97]. Overall, 52% (79) partners in the HIVST strategy tested vs 38% (60) in the invitation strategy (adjOR: 1.78, 95% CI: 1.13 to 2.78). Among partners engaged, 73% in the HIVST strategy vs 50% in the invitation tested (adjOR: 2.68, 95% CI: 1.46 to 4.96); 25% (35/139) tested positive for HIV. Eighty-nine percentage (31/35) who tested positive initiated treatment, but only 21% (20/93) who tested negative initiated PrEP.

Conclusions:
HIVST kit distribution to PLHIV with partners of unknown HIV status effectively increased partner testing. Only one-fifth of partners who tested negative initiated PrEP—thus innovations to link to prevention services are urgently needed.
Consumer behaviour towards storage, disposal and recycling of e-waste: systematic review and future research prospects
Authors: Thukral Sonal , Shree Deep , Singhal Shakshi 
Published: April 2022

PurposeWith the rapid increase in the consumption of electrical and electronic innovations, responsible management and recycling of electronic waste (e-waste) or waste electrical and electronic equipment (WEEE) has been a significant concern for the governments, stakeholders, researchers and industry practitioners around the world. Consumer awareness, disposal behaviour and perception are chief facets of designing sustainable management strategies. Although researchers have widely studied e-waste over many years, the research focusing on consumer awareness about e-waste recycling has gained momentum recently. This paper aims to systematise the existing literature and explore future research prospects on household e-waste sorting behaviour.Design/methodology/approachWeb of science (WoS) core collection was searched using selected keywords to identify relevant articles published from 2001 to 2021. The search resulted in 1,156 research articles published from 2001 to 2021. After a detailed study, 85 articles were shortlisted for in-depth review. The review was conducted based on global trends, top journals, most prolific authors, most active e-waste research countries, and institutions centring on consumer participation in e-waste disposal and recycling behaviour. The present research has also identified around eleven factors that seem to have a bearing on consumer behaviour towards storage, disposal and recycling of e-waste.FindingsE-waste research has gained increased attention in the last five years. The majority of the studies has focused on motivational factors and ignore the risks associated with handling e-waste. The present study reports the pertinent issue of lack of awareness among the masses about e-waste handling and disposal. Thus, bringing to the fore the lack of awareness programmes and initiatives. The analysis presents the gaps in the literature and future research agendas.Originality/valueThe review article will help in providing an in-depth understanding of consumer behaviour towards storage, disposal and recycling of e-waste and delineates the future direction of research that may be undertaken in this field of study.
Blended learning in entrepreneurship education: a systematic literature review
Authors: Viebig Christoph 
Published: April 2022

PurposeCurrent research lacks a clear definition of blended learning in entrepreneurship education (EE), a comprehensive overview of the recent research, and a conceptualization of different types of blends with their respective challenges and advantages. In response to that, the author systematically reviewed the literature on blended learning in EE and developed four archetypes of blends for entrepreneurship educators.Design/methodology/approachThe author conducted a systematic literature review and identified 75 relevant peer-reviewed articles published between 2004 and 2021.FindingsThe findings suggest that blended learning is a common yet underexplored and undertheorized phenomenon in EE. The findings display the rationale and motives, educator characteristics, content, teaching methods, student characteristics, and results of blended learning in EE.Originality/valueThe paper is original because it posits blended learning as an independent and unique mode of delivery in EE. In addition, the author suggests four archetypes of blends in EE: the traditional blend, the for-action blend, the in-action blend, and the experiential blend. For each of these blends, the author identified specific advantages and challenges and discussed under which circumstances educators may employ them.
Sometimes it works: the effect of a reform of the short vocational track on school-to-work transition
Authors: Comi Simona Lorena , Grasseni Mara , Origo Federica 
Published: April 2022

PurposeThe purpose of this paper is to use the two-way fixed effect (TWFE) methodology to estimate the impact of the reform, exploiting its staggered implementation across regions. The analysis is restricted to graduates from the short vocational track before and after the reform.Design/methodology/approachThis paper studies the impact on the length of school-to-work transition of a reform that extended from two to three years the short vocational track in Italy in the early 2000s.FindingsThe study finds that the reform had a positive impact and reduced school-to-work transition by around five months (a 24% reduction). Moreover, the new short vocational track proved to be extremely effective for migrants and females, whose school-to-work transition was reduced by 1.4 years and 0.9 years, respectively. In implementing the new short vocational track, some regions adopted a quasi-market organization in which private training institutions competed with public schools. This model proved to be more effective in shortening school-to-work transitions, in particular for migrants.Originality/valueThis study makes an important contribution to the literature on the labor-market effect of vocational education by showing that lengthening the short vocational track, and changing the overall content of curricula, can speed up school-to-work transition.
This brand is who I am… or is it? Examining changes in motivation to maintain brand attachment
Authors: Davis Svetlana V. , Dacin Peter A. 
Published: April 2022

Purpose
The purpose of this paper is to investigate consumer motivation to maintain brand attachment when faced with brand transgressions. This study investigated consumer motivation to maintain brand attachment when faced with brand transgressions.

Design/methodology/approach
This study consisted of two experiments using student participants (n1 = 383 and n2 = 535) who examined how, from a customer prioritization strategy, perceived value- and image-based transgressions affect the motivation to maintain brand attachment and subsequent behaviors. Hypotheses were developed and tested using moderating mediation models that included attribution of blame and perceived threat.

Findings
Value- and image-based transgressions interacted to affect the motivation to maintain brand attachment and the consequent behavioral intentions among consumers with strong brand attachment. Generally, the interaction had a negative effect on motivation to maintain brand attachment; however, this effect was mediated through perceived threat and moderated by attributions of blame. Depending on the level of motivation to maintain brand attachment and the attribution of blame for the brand transgression (the brand, self- or noncontrollable factors), participants reflected different behavioral intentions: reengagement, contention and/or avoidance. Overall, severe value-based transgression coupled with absence (vs presence) of image-based transgression were perceived more threatening by consumers with strong brand attachment leading to lower motivation to maintain attachment and higher intentions to dissolve the relationship.

Originality/value
Little is known about the conditions that increase or decrease the motivation of strongly attached consumers to maintain their attachment. To the best of the authors’ knowledge, this is the first study to explore the potential effects of brand transgressions on the motivation to maintain brand attachment and the consequent behavioral intentions stemming from perceived transgressions.
The effect of debt maturity structure on earnings management strategies
Authors: Draief Sondes , Chouaya Adel 
Published: April 2022

PurposeThe aim of this study is to investigate whether debt maturity matters for the choice of earnings management strategy (i.e. accruals earnings management and real earnings management).Design/methodology/approachThe sample involves 486 American listed firms extracted from fortune 1,000 over the period 2006–2014. Panel data regression models are employed to empirically test the impact of short-term debt and long-term debt on manager's choice of earnings management form. The generalized least square technique is applied to estimate the parameters of the regression models.FindingsThe results show that managers are more likely to manage earnings through real activities and reduce their use of accruals earnings management once short debt is increasing because the latter induces heavy lender's scrutiny. The managers move hence to real earnings management due to a lower possibility of being discovered. Moreover, the results reveal a simultaneous use of accruals earnings management and real earnings management for firms with high long-term debt. This finding highlights that long-term debt does not produce regular lender's enforcement allowing managers to use both earnings management techniques to reach earnings targets.Research limitations/implicationsThis research has two limitations. Like many other studies, the measure of discretionary accruals is subject to measurement errors. Moreover, the sample exclusively involves large firms extracted from Fortune 1,000. Therefore, the attained results may be not available for small and medium firms.Practical implicationsThe findings have implications for both researchers and lenders. For researchers, the present work points out that the decision about the debt maturity structure is crucial for all managers because they establish their earnings management policy accordingly. For lenders, the findings imply that increasing scrutiny effectively constrains accounting manipulations but does not eliminate earnings management activities altogether. The managers move to another earnings management strategy (i.e. real earnings management). This evidence may support the lenders and the creditors in their decision-making processes.Originality/valueThis paper adds to the accounting literature by providing new and interesting evidence on the role of debt maturity on the trade-off between the earnings management tools. Prior studies provided mixed finding for the issue of earnings management in levered firms. The findings of this study should be viewed as a first step to understand the mixed results on this issue. While most papers focus on one earnings management form when they examine the earnings management in levered firms, the authors highlight the impact of debt on both accruals and real earnings management simultaneously.
Three leadership assessment tools for managers
Authors: Timms Michael 
Published: April 2022

Purpose
This paper aims to explain the importance for managers to request feedback as a way to improve their leadership skills.

Design/methodology/approach
The author provides a series of tips on requesting feedback, based on his consulting experience and academic research.

Findings
The author gives readers an array of tips and exercises for managers to request feedback at their organizations.

Originality/value
This paper will prove valuable for readers who are in a leadership position or looking to improve upon their ability to be accountable.
Motivated to share? Development and validation of a domain-specific scale to measure knowledge-sharing motives
Authors: Fischer Caroline 
Published: April 2022

Purpose
This paper aims to develop and validate a scale to measure knowledge-sharing motives at work. It is aimed to construct a scale which is explicitly different from knowledge-sharing behavior and to develop a comprehensive and domain-specific scale for this special kind of work motivation.

Design/methodology/approach
The constructed scale was tested in two studies. Survey data (n = 355) were used to perform an exploratory factor analysis. Results were further tested on survey data from the core public sector (n = 314) and the health sector (n = 315). A confirmatory factor analysis confirms the results in both samples. The developed scale was further validated internally and externally.

Findings
The analysis underlines that knowledge-sharing motivation and knowledge-sharing behavior are different constructs. The data suggest three dimensions of knowledge-sharing motives: appreciation, growth and altruism and tangible rewards. While it is suggested that the developed scale works in the public as well as the private sector context, it is found that knowledge sharing of public employees is merely driven by “growth and altruism” and “appreciation of coworkers.”

Originality/value
No comprehensive and reproducible scale to measure knowledge-sharing motives, which is different from behavior and domain-specific as well, was available in the literature. Therefore, such a scale has been constructed in this study. Furthermore, this study uses samples from different organizational sectors to deepen the understanding of knowledge sharing in context.
Severe cutaneous adverse reactions associated with systemic ivermectin: A pharmacovigilance analysis
Authors: Bomze David , Sprecher Eli , Geller Shamir 
Published: April 2022

AbstractDespite poor evidence, the antiparasitic ivermectin has been advocated as a potential COVID‐19 therapy. This has led to a rise in calls to poison‐control centers by people self‐medicating with ivermectin, which is sold over the counter for veterinary uses. We aimed to investigate the association between severe cutaneous adverse reactions (SCARs) and ivermectin. Postmarketing data from the FDA Adverse Event Reporting System (FAERS), gathered between 2014 and 2021, was employed to detect disproportional signals of SCARs following systemic ivermectin therapy. The reporting odds ratio (ROR) was used to quantify the strength of association, while adjusting for age, sex, and region. The search yielded 517 reports of systemic ivermectin (median age 54 years, 46.8% female), of which 25 (4.8%), 81 (15.7%), and 411 (79.5%) were classified as SCARs, nonsevere cutaneous adverse events (AEs), or noncutaneous AEs, respectively. The regional distribution differed between SCAR reports (32.0% from Africa and 12.0% from North America) compared with other AEs, which originated from North America in over half of cases. The most common SCARs were toxic epidermal necrolysis (seven cases), Stevens–Johnson syndrome (seven cases), and drug reaction with eosinophilia and systemic symptoms (four cases). Five SCAR cases (20.0%) resulted in death and 12 (48.0%) lead to hospitalization. There was a strong safety signal for any SCAR (adjusted ROR 3.34, 95% confidence interval [CI] 2.17–5.12) and toxidermias (adjusted ROR 7.08, 95% CI 4.23–11.84). This study suggests that ivermectin is associated with SCARs on rare occasions. Dermatologists should be aware of this given the increase in ivermectin misuse.
Marked safety and high diagnostic yield of freehand ultrasound‐guided core‐needle biopsies performed by pulmonologists
Authors: Gershman Evgeni , Vaynshteyn Ilya , Freidkin Lev , Pertzov Barak , Rosengarten Dror , Kramer Mordechai Reuven 
Published: April 2022

AbstractBackgroundAdequate tissue sampling is fundamental for establishing a definitive diagnosis, assessing prognosis and tailoring therapy. Each of the methods for obtaining tissue (e.g., endoscopic, image guidance and surgical biopsies) results in a different diagnostic yield and complication rate profile.ObjectivesPresent feasibility, and assess safety and efficacy of freehand transthoracic ultrasound‐guided core‐needle biopsies (USGNB) of thoracic lesions performed by pulmonologist.MethodsA retrospective analysis study of ultrasound‐guided core‐needle biopsies of thoracic lesions performed at the Pulmonary Institute of Rabin Medical Center was conducted from September 2020 to October 2021. All core‐needle biopsies were performed under local anesthesia with guidance of Mindray TE7 2019 US system. Procedural variables including complications and pathological diagnostic yield were the primary end point. IRB 0671‐21‐RMC.ResultsIn total 91 biopsy procedures were analyzed in38 females and 53 males, average age 71.1 years. Twenty‐three (25.3%) cases were lung lesions, 7 (7.7%) – mediastinal, 13 (14.3%) – chest wall, 27 (29.7%) – pleural, and 21 (23.1%) supraclavicular lesions. Average lesion size was 51.6 mm, the largest in the mediastinum and the smallest in supraclavicular locations (97.7mm and 28.0 mm, respectively). Overall pathological diagnostic yield was 90%, highest success in chest wall (100%) and lowest in mediastinal biopsies (71.4%). We had only one complication –hemothorax resolved by chest tube drainage‐ accounting for only 1.1% complication rate.ConclusionSafety and efficacy were demonstrated in freehand US‐guided core‐needle biopsy of thoracic lesions performed by pulmonologists. We suggest thoracic ultrasound and USG‐CNB be part of training and clinical practice in interventional pulmonology.
Candy‐striped spider leaf and habitat preferences for egg deposition
Authors: Cuff Jordan P. , Evans Sharon Aifionn , Porteous Ian Angel , Quiñonez Julia , Evans Darren M. 
Published: April 2022

Abstract
Candy‐striped spiders (Enoplognatha spp.; Araneae: Theridiidae) are among Britain's commonest theridiid spiders and are potential immigrant biocontrol agents of many pests in arable fields. Though the presence of these spiders in proximity to agriculture is dependent on the availability of suitable leaves for their egg deposition, their preference for different plant species and habitat types has not been fully investigated.
Candy‐striped spiders were observed in leaf‐rolls during transect surveys of semi‐natural habitats (hedgerow, woodland and grassland) adjacent to oilseed rape fields at 10 sites across northeast England in August and September 2021. The local plant community was surveyed and compared against the leaves used by candy‐striped spiders via null models.
Candy‐striped spiders preferentially deposited their eggs in hedgerow, demonstrating relative avoidance of woodland and grassland. They exhibited preference for bramble, common nettle and hogweed leaves, but also used those of dock, ash and blackthorn. Candy‐striped spiders appeared to preferentially use leaves with roughly equal length and width and avoided longer, narrower leaves irrespective of their total size.
The leaves used by candy‐striped spiders are taxonomically broad, but share some morphological commonalities. Candy‐striped spiders exhibit some degree of generalism, regularly utilizing suboptimal leaves in sites lacking their preferences. The availability of preferred plants for these spiders in agriculturally proximate semi‐natural habitat may enhance their possible contribution to biocontrol.
Response to ‘Isotretinoin and adverse neuropsychiatric outcomes: retrospective cohort study using routine data’
Authors: Chang Renin , Lai Chih-Cheng , Hung Yao-Min , Wang Shiow-Ing , Wei James Cheng-Chung 
Published: April 2022

Abstract
Linked Article: Paljarvi et al. Br J Dermatol 2022; 187:64–72.
Safety and efficacy of fedratinib, a selective oral inhibitor of Janus kinase‐2 (JAK2), in patients with myelofibrosis and low pretreatment platelet counts
Authors: Harrison Claire N. , Schaap Nicolaas , Vannucchi Alessandro M. , Kiladjian Jean‐Jacques , Passamonti Francesco , Zweegman Sonja , Talpaz Moshe , Verstovsek Srdan , Rose Shelonitda , Zhang Jun , Sy Oumar , Mesa Ruben A. 
Published: April 2022

SummaryFedratinib, an oral Janus kinase‐2 (JAK2) inhibitor, is approved for patients with myelofibrosis (MF) and platelet counts ≥50 × 109/l, based on outcomes from the phase 3, placebo‐controlled JAKARTA trial in JAK‐inhibitor‐naïve MF, and the phase 2, single‐arm JAKARTA2 trial in patients previously treated with ruxolitinib. We evaluated the efficacy and safety of fedratinib 400 mg/day in patients with baseline platelet counts 50 to <100 × 109/l (“Low‐Platelets” cohorts), including 14/96 patients (15%) in JAKARTA and 33/97 (34%) in JAKARTA2. At 24 weeks, spleen response rates were not significantly different between the Low‐Platelets cohort and patients with baseline platelet counts ≥100 × 109/l (“High‐Platelets” cohort), in JAKARTA (36% vs. 49%, respectively; p = 0.37) or JAKARTA2 (36% vs. 28%; p = 0.41). Symptom response rates were also not statistically different between the Low‐ and High‐Platelets cohorts. Fedratinib was generally well‐tolerated in both platelet‐count cohorts. New or worsening thrombocytopaenia was more frequent in the Low‐Platelets (44%) versus the High‐Platelets (9%) cohort, but no serious thrombocytopaenia events occurred. Thrombocytopaenia was typically managed with dose modifications; only 3/48 Low‐Platelets patients discontinued fedratinib due to thrombocytopaenia. These data indicate that fedratinib 400 mg/day is safe and effective in patients with MF and low pretreatment platelet counts, and no initial fedratinib dose adjustment is required for these patients.