bluuebunny/crossref_metadata_2025_split huggingface dataset:
Activities Performed by ASCO-Sponsored Oncology Student Interest Groups in Latin America: Assessing Members' Preferences and Leaders' Challenges
Authors: Núñez-Peña Emilia , Siller-Garcia Paloma , Vaca-Cartagena Bryan F. , Lucio-Lozada Jose , Villafuerte-Manrique Silvia , Barrera López Mirelle , Mesa-Chavez Fernanda , Villarreal-Garza Cynthia 
Published: October 2022

PURPOSE In response to the worldwide shortage of oncologists, ASCO established Oncology Student Interest Groups (OSIGs) to increase oncology exposure at medical schools. However, there is limited guidance on the activities they should undergo. The main purposes of this study were (1) to assess the preferences and perceptions of OSIG members about their group events and (2) to describe the difficulties faced by leaders to carry out OSIGs' tasks. METHODS In this multicenter, cross-sectional study, group members and leaders from five active Latin American OSIGs were invited to answer anonymous web-based surveys exploring members' attitudes toward group activities and leaders' challenges when carrying them out. Data collection was conducted from March to June 2021. RESULTS Responses from 142 medical students and four OSIGs leaders were analyzed. In total, 83% of student members considered that lectures with an oncology-related expert was very useful for increasing their overall interest in oncology. For increasing interest in cancer research, 87% deemed that participating in oncology research projects was very useful. Shadowing oncology professionals was very useful for at least 70% of members to increase their oncology knowledge and their interest in following an oncology-related career. Moreover, leaders' main challenges were having a high academic load, little response from members, lack of interesting ideas and protected time for OSIGs' events, and limited support from their school. CONCLUSION OSIGs' leaders, medical schools, and international oncology organizations should work together to design activities that increase medical students' exposure to oncology-related professionals and encourage their participation in international oncological events. These schools and organizations should actively support OSIG leaders when facing difficulties to prevent members' disengagement and groups' discontinuation.
Risk Factors, Hyaluronidase Expression, and Clinical Immunogenicity of Recombinant Human Hyaluronidase PH20, an Enzyme Enabling Subcutaneous Drug Administration
Authors: Printz Marie A. , Sugarman Barry J. , Paladini Rudolph D. , Jorge Michael C. , Wang Yan , Kang David W. , Maneval Daniel C. , LaBarre Michael J. 
Published: October 2022

AbstractMultiple FDA-approved and clinical-development stage therapeutics include recombinant human hyaluronidase PH20 (rHuPH20) to facilitate subcutaneous administration. As rHuPH20-reactive antibodies potentially interact with endogenous PH20, we investigated rHuPH20 immunogenicity risk through hyaluronidase tissue expression, predicted B cell epitopes, CD4+ T cell stimulation indices and related these to observed clinical immunogenicity profiles from 18 clinical studies. Endogenous hyaluronidase PH20 expression in humans/mice was assessed by reverse transcriptase-polymerase chain reaction (RT-PCR), quantitative RT-PCR, and deep RNA-Seq. rHuPH20 potential T cell epitopes were evaluatedin silicoand confirmedin vitro. Potential B cell epitopes were predicted for rHuPH20 sequencein silico, and binding of polyclonal antibodies from various species tested on a rHuPH20 peptide microarray. Clinical immunogenicity data were collected from 2643 subjects. From 57 human adult and fetal tissues previously screened by RT-PCR, 22 tissue types were analyzed by deep RNA-Seq. Hyaluronidase PH20 messenger RNA expression was detected in adult human testes.In silicoanalyses of the rHuPH20 sequence revealed nine T cell epitope clusters with immunogenic potential, one cluster was homologous to human leukocyte antigen. rHuPH20 induced T cell activation in 6–10% of peripheral blood mononuclear cell donors. Fifteen epitopes in the rHuPH20 sequence had the potential to cross-react with B cells. The cumulative treatment-induced incidence of anti-rHuPH20 antibodies across clinical studies was 8.8%. Hyaluronidase PH20 expression occurs primarily in adult testes. Low CD4+ T cell activation and B cell cross-reactivity by rHuPH20 suggest weak rHuPH20 immunogenicity potential. Restricted expression patterns of endogenous PH20 indicate low immunogenicity risk of subcutaneous rHuPH20.Graphical abstract
TERF or Transfeminist Avant la Lettre?
Authors: Provitola Blase A. 
Published: October 2022

Abstract
French lesbian author and theorist Monique Wittig's early contestations of woman as the subject of feminism have played an important role in gender studies in both anglophone and francophone spaces. Since the mid-1990s, French lesbian studies scholars and queer theorists alike have looked to her to anchor their contestations of normative sexuality within a French tradition and counter some of the universalizing aspects of Anglocentric queer theory. As a result, polarizing debates have sprung up over interpretations of Wittigian political lesbianism, typically focusing on divergent readings of her theorization of sex and gender between radical lesbians on the one hand and queer theorists on the other. However, far less attention has been paid to the implications of such debates for transgender studies. Since she has been claimed by trans-exclusionary radical feminists as well as by queer and materialist transfeminists in France, her legacy serves as a rich site through which to understand how the ideological conflicts between those groups relate to feminist history. Taking as a point of departure the appropriation of her name by the anti-trans group Résistance Lesbienne (Lesbian Resistance) that took over the 2021 Paris Pride March, this article fleshes out the implications of her work concerning the place of transgender people, and especially transgender women, in feminist spaces. Ultimately, it is her complexity that makes her a crucial figure for transgender studies insofar as she elucidates French “gender-critical” feminism and its transfeminist critics.
The Characteristics of Thermal Runaway and Its Propagation in Large-Format LiFePO4 Batteries under Overcharging and Overheating Conditions
Authors: Zhang Tao , Qiu Xiangyun , Wei Tao 
Published: October 2022

Abstract
LFP batteries are widely used in energy storage stations and electric vehicles, but their related fire incidents have not been remediated. In this paper, the TR/TRP characteristics of LFP batteries/modules under different heat dissipation conditions are investigated through experiments and simulations. In addition, the TRP behaviour of large-capacity prismatic LFP modules under different SOCs and TR trigger modes is investigated in detail. It is found that the heat dissipation significantly affects the maximum TR temperature of the LFP single battery under overheating and whether TR occurs under overcharging. Besides, whether improving the convection coefficient can prolong the TRP time of the LFP module under overheating is influenced by the thermal resistance value between adjacent batteries. Furthermore, the TRP behaviour of the LFP module is significantly influenced by the SOC and TR trigger mode. 100% SOC LFP modules have the most intense TRP behaviour under overheating, with the TRP time increasing from 140 s to 644 s as the battery SOC drops from 100% to 80%, and TRP being blocked as the battery SOC drops to 50%. The LFP module however does not undergo TRP under overcharging even in an open environment at 80 °C.
Αντίληψεις και πρακτικές εκπαιδευτικών πρωτοβάθμιας εκπαίδευσης σχετικά με τη διαχείριση της ψυχικής υγείας παιδιών προσφύγων που φοιτούν στις Δομές Υποδοχής και Εκπαίδευσης Προσφύγων στην Ελλάδα
Authors: Γαλάνη Μαρία , Σταυρινίδης Παναγιώτης 
Published: October 2022

Στόχος αυτής της έρευνας είναι η ανάδειξη εμπειριών των εκπαιδευτικών πρωτοβάθμιας εκπαίδευσης που έχουν εκτελέσει εκπαιδευτικό έργο σε Δομές Υποδοχής και Εκπαίδευσης Προσφύγων (ΔΥΕΠ) στην Ελλάδα. Ουσιαστικά, καταγράφονται οι απόψεις τους σχετικά με την ψυχική υγεία των παιδιών προσφύγων που συναντούν και μελετώνται οι πρακτικές που υιοθετούν στην προσπάθειά τους να υποστηρίξουν την ψυχοσυναισθηματική κατάσταση των παιδιών που φοιτούν στις δομές. Στην έρευνα συμμετείχαν 15 εκπαιδευτικοί πρωτοβάθμιας εκπαίδευσης οι οποίοι τοποθετήθηκαν σε ΔΥΕΠ κατά τη διάρκεια των σχολικών ετών 2018 – 2019, 2019 – 2020 και 2021-2022. Πρόκειται για μια ποιοτική έρευνα, όπου χρησιμοποιήθηκε ως μέθοδος συλλογής των δεδομένων η ημι-δομημένη συνέντευξη. Τα ερευνητικά δεδομένα αναλύθηκαν μέσω της ερμηνευτικής φαινομενολογικής προσέγγισης. Από τα ευρήματα της έρευνας αναδεικνύονται ως κυριότεροι παράγοντες επικινδυνότητας για την ψυχική υγεία των παιδιών προσφύγων το σχολικό περιβάλλον, η κουλτούρα της οικογένειας και ο ρατσισμός από τη χώρα υποδοχής. Ακόμα, μέσα από τα βιώματα των εκπαιδευτικών παρουσιάζονται οι ψυχοσυναισθηματικές δυσκολίες των παιδιών προσφύγων όπως μετατραυματικό στρες, επιθετικότητα, παρορμητικότητα και ανασφάλεια δημιουργίας σχέσεων. Τέλος, εξετάζεται ο όρος της ψυχικής ανθεκτικότητας και προκύπτουν μαρτυρίες για ψυχικά ανθεκτικά παιδιά, που παρά τις αντιξοότητες και τις φρικαλεότητες που έχουν βιώσει παρουσιάζουν θετική προσαρμογή και ψυχολογική επάρκεια.
Methods of Improving IT Project Management Processes
Authors: Grigorian Ilia 
Published: October 2022

The topic of the article as well as the issues concerning the ways to improve IT-project management processes are becoming more and more relevant, the need to respond effectively to the changing national and international challenges of external conditions is increasing. Therefore, a detailed structural study and elaboration of ways to improve IT project management processes are required.
This study focuses on ways to improve IT project management processes.
The research methods are theoretical methods: analysis of sources, systematization and generalization.
The author of the article gives an interpretation of the concept "IT-project", "IT-project management".
The article analyzes the problems of IT-project management in modern organizations.
It characterizes the existing methods of IT-project management, as well as proposes new ways of managing IT-projects: the use of a unified information system, the model of "7 K-questions", the map of competencies in selecting the team.
Motywacje twórcze autorów emigracyjnego dokumentu osobistego. Przykład Henryka Przyborowskiego
Authors: Lewandowski Wacław 
Published: October 2022

Artykuł przynosi rewizję pojęcia „literatura dokumentu osobistego” w zastosowaniu do literatury Drugiej Emigracji, polegającą na zaliczeniu do literatury dokumentarnej także utworów genologicznie niejednorodnych, hybrydycznych. Na przykładzie Raportu karnego H. Przyborowskiego autor stara się ukazać motywacje twórcze nieprofesjonalnych twórców tego typu piśmiennictwa.
„Emigrantka z emigracji”. 39 lat pobytu Alicji Iwańskiej w Stanach Zjednoczonych w świetle pamiętnika „Potyczki i przymierza”
Authors: Wal Anna 
Published: October 2022

Artykuł został poświęcony obrazowi emigracji, jaki w pamiętniku Potyczki i przymierza (1993), a ściślej w części zatytułowanej Ameryka (1946–1985), przedstawiła Alicja Iwańska, polska pisarka, socjolożka, przez wiele lat pracująca w amerykańskich uniwersytetach. Ukazany w pamiętniku pobyt na emigracji jego autorki omówiono jako doświadczenie egzystencjalne związane z opuszczeniem kraju urodzenia i próbą zakorzenienia się w nowym miejscu. Przedmiotem uwagi był przebieg adaptacji do nowych warunków w Stanach Zjednoczonych, jego poszczególne etapy oraz proces konstytuowania się emigracyjnej tożsamości narratorki Potyczek i przymierzy, reprezentującej powojenną emigrację inteligencką. Kolejnymi zagadnieniami, które objęto refleksją, był krytyczny stosunek Iwańskiej do Stanów Zjednoczonych, manifestujący się w sposobie opisu tego kraju w pamiętniku, a także dystans do instytucji i organizacji reprezentujących Polaków zamieszkujących Stany Zjednoczone. Do tego ostatniego wątku odnosi się tytuł artykułu – „emigrantka z emigracji”. Interpretacja pamiętnika Potyczki i przymierza prowadzi do wniosku, że jego powstawanie pozwoliło Iwańskiej dokonać uniwersalizacji nie tylko doświadczenia emigracyjnego, ale całego dotychczasowego (wówczas z perspektywy 67 lat) życia i spojrzeć na nie w kategorii losu, czemu dała wyraz w „Prologu”, gdzie swój los określiła jako „łazęgowanie”.
Absolwenci przedwojennej Szkoły im. Sułkowskich w Rydzynie – między patriotycznym obowiązkiem a emigracją
Authors: Tobolska Ewelina 
Published: October 2022

W latach 1928–1939 istniało w Polsce męskie Gimnazjum i Liceum im. Sułkowskich w Rydzynie, którego główną ideą było wychowanie nowego pokolenia inteligencji polskiej. Eksperymentalny program Szkoły dążył do uformowania klasy społecznej o wysokich standardach moralnych, odpowiedzialnej za naród i zdolnej do bezinteresownej służby społecznej. Twórcą pedagogicznego programu był Tadeusz Łopuszański, minister oświaty w rządzie Władysław Grabskiego, reformator szkolnictwa polskiego, autor całościowego programu edukacyjno-wychowawczego dla szkół średnich. Wśród znanych absolwentów Szkoły w Rydzynie byli m.in.: prof. Józef Zwisłocki, Konstanty Jeleński, Aleksander Łempicki, Bolesław Biega, Franciszek Walicki, Zbigniew Ścibor-Rylski, prof. Władysław Górski, prof. Zbigniew Tadeusz Wierzbicki, Jan Sosnkowski. Artykuł przybliża sylwetki kilku absolwentów Szkoły, ich historie i emigracyjne zmagania, a także poddaje refleksji czynniki, które doprowadziły do wytworzenia ponadczasowej więzi między uczniami (Rydzyna-Szkoła jako ,,miejsce pamięci”). Opierając się na dostępnych listach, biografiach, wspomnieniach, przedstawiono niezwykłą grupę emigrantów, której spoiwem była Szkoła w Rydzynie. Analizie poddano sytuację wyboru między wpojonym w okresie szkolnym wzorem patriotycznego zachowania a emigracją i życiową realizacją odebranego w Szkole wychowania moralnego.
„O honor” (1950) Jakuba Herziga, (nie)znany dramat na temat powstania w getcie warszawskim
Authors: Gardocki Wiktor 
Published: October 2022

W artykule przedstawiono dzieje dramatu pt. O honor…, a także losy jego autora, Jakuba Herziga (1887–1956). Przeżył on Holokaust na ziemiach polskich, bardzo często zmieniając miejsce zamieszkania. Był świadkiem wielu dramatycznych wydarzeń, z których relacje starał się zdać już po wojnie. Pozostawił po sobie kilka obszernych utworów literackich, w tym – prawdopodobnie nigdy niepublikowany w języku polskim – dramat O honor…, podejmujący temat powstania w getcie warszawskim z perspektywy żydowskich bojowców. Utwór jest wprawdzie niedoskonały literacko, jednak niezwykle cenny i interesujący jako świadectwo Zagłady. W artykule opisano także inne utwory Herziga, przekazane w postaci maszynopisów do Jad Waszem. Część z nich ukazała się później w Nowym Jorku i Tel Awiwie.
Dysphoric milk ejection reflex as a new diagnostic and therapeutic challenge in lactation care - literature review
Authors: Skowrońska Katarzyna , Chmura Anna , Baciur Patrycja , Środoń Agnieszka 
Published: October 2022

Introduction and purpose of the work: Breastfeeding has many health benefits. The guidelines recommend breastfeeding up to 6 months of age. Many mothers stop breastfeeding early, one reason being the dysphoric ejection reflex (D-MER). It is a negative emotional reaction related to the ejection of milk.
State of knowledge : D-MER has been known to science for a short time. Breastfeeding depends on many psychological factors and is regulated by many hormones, including prolactin, oxytocin, and dopamine. A sudden drop in dopamine levels is believed to be the cause of this phenomenon. The main symptoms include dysphoria, sadness, irritability, anxiety and depression. There are no registered preparations for the treatment of D-MER, psychotherapy and lifestyle changes are helpful.
Summary: It is important to disseminate knowledge about D-MER to help mothers understand their breastfeeding processes. More research should be done into the safe treatment of this condition.
Removing Out-of-Condition Grain: An Exploration and Documentation of Existing Strategies
Authors: Issa Salah F. , Gaither Daniel , Raza Mian Muhammad Sajid , Lee John , Field William E. 
Published: October 2022

HighlightsDifferent approaches used to handle out-of-condition grain can be split into three broad categories: outfitting, outside, and inside the bin.A total of 21 strategies to handle out-of-condition grain are documented in this article.Outside the bin strategies are split into four categories: grain handling solutions, rodding, force-based solutions, and alternate grain extraction methods.Abstract. Grain entrapments remain a major concern in the grain storage and handling industry. Even with the adoption of safer technology, enhanced enforcement of OSHA regulations, and considerable investment in training and outreach efforts, grain entrapments continue to occur in significant numbers. The most significant contributing factor to grain entrapment is the presence of out-of-condition grain. A better understanding of existing strategies employed to remove out-of-condition grain from storage is important to provide evidence-based solutions to reduce the perceived need to enter grain storage structures and the grain entrapment associated with this activity. A review of existing strategies for handling out-of-condition grain used previously by farmers and workers with experience in grain storage facilities was conducted. Training programs, extension resources, and published research were reviewed to document existing strategies to remove out-of-condition grain. These strategies were split into three broad categories: outfitting the bin, outside of the bin, and inside the bin. A total of 21 strategies were documented. Each of the strategies was defined and, where possible, the risks and benefits were discussed. The study highlights the importance of researching the safety and effectiveness of each of these strategies in various out-of-condition grain situations and the lack of available knowledge of the effectiveness of each strategy. Keywords: Engulfment, Entrapment, Inside the bin strategies, Outfitting the bin strategies, Out-of-condition grains, Outside the bin strategies, Spoiled grains, Storage.
Extended Technology Acceptance Model (TAM2) to Understand Decision Making for Grain Bin Hazards Among Texas Farmers
Authors: London Cara , Moore Janie McClurkin 
Published: October 2022

HighlightsHazard exposure is not enough to catalyze adoption of grain bin temperature probes.Perceived ease of use significantly influenced farm technology adoption among Texas farmers.Demonstrated that low barriers to access and configuration into current farm operations will increase adoption of life-saving technologies. ABSTRACT.This research aimed to understand the profile of temperature probe adopters as compared to non-adopters in the context of preventing grain bin deaths. Our analysis is based on a unique data set obtained from a survey of 54 farmers from Texas. The survey was built using the TAM2 model as a foundation. We employed standard regression models to identify factors that contributed to the adoption of temperature probes among other technologies. We found that hazard exposure was not a predictor for temperature probe adoption. Network relationships also did not significantly influence adoption. Technology adoption was predicted by six perceptions: subjective norms, image (status), quality of the technology, access to the technology, access to information about the technology, and compatibility. The findings of this study suggest that instead of the current safety advice used to convince farmers to use grain bin probes, stakeholders should inform them about the direct positive results of using the probes. Current campaigns against grain bin entrapment should emphasize through demonstration the benefits of grain bin probes on stored grain products. Although extension and private offices may not directly impact the final decision making, they should seriously consider expending the effort to lower the barrier to access to positively influence the adoption rate. Keywords: Adoption, Agricultural extension, Behavior model, Decision making factors, Grain entrapment, Grain quality, Safety, TAM2, Technology.
A Test of Social Cognitive Theory to Increase Hearing Protection Use in Swine Buildings
Authors: Rudolphi Josie , Campo Shelly , Janssen Brandi , Ramirez Marizen , Wang Kai , Rohlman Diane 
Published: October 2022

HighlightsAlmost 50% of participants reported engaging with the smartphone app Habitbull daily. Access to high-quality hearing protection devices may be enough to change behaviors towards hearing protection device use among young adults. Abstract. Farming ranks among the top occupations for which workers are at risk for noise-induced hearing loss (NIHL), an irreversible yet preventable condition. Hearing Protection Devices (HPDs) (i.e., earmuffs and ear plugs) are effective at preventing exposure to noise; however, few farmers report consistent use.The purpose of this study was to test an intervention based on Social Cognitive Theory with interactive smartphone technology to increase the use of HPDs among swine facility workers.A pilot, quasi-experimental study was implemented among 72 younger adult swine workers. Participants were randomly assigned to one of three groups. Group 1 received HPDs (e.g., earmuffs and ear plugs). Group 2 received the same HPDs as Group 1 and was also instructed to use a smartphone application to track their use of hearing protection for 60 days. Group 3 received the HPDs and instructions on using a smartphone app for tracking the use of hearing protection and setting daily goals for hearing protection use. Use of hearing protection was assessed via an online survey prior to the intervention (i.e., “baseline”), immediately after the post-intervention, and at a 3-month follow-up.Compared to baseline use, all three groups reported increased use of hearing protection immediately post-intervention. However, this increase was not maintained at a 3-month follow-up for two of the study groups. Group 3 (HPD, tracking, and goal-setting app) showed the greatest increase in the use of HPDs from baseline to immediate post-intervention; however, Group 1 (HPD only) showed the greatest sustained increase from baseline to the 3-month follow-up. Modifying the environment by supplying HPDs was effective in increasing HPD use among swine facility workers. Improving access to hearing protection devices alone may lead to sustained changes in behavior. Keywords: Agricultural safety and health, Hearing protection, Noise-induced hearing loss, Young adult workers.