bluuebunny/crossref_metadata_2025_split huggingface dataset:
La tentation mystique ? L’argumentation de La mort à Paris
Authors: Roullet Antoine 
Published: November 2022

Ce chapitre s’intéresse à l’argumentation de Pierre Chaunu à l’heure de réfléchir au problème de la mort, abordé par lui d’une manière bien différente des autres historiens qui, dans les années 1960-1970, s’étaient confrontés au problème. Chaunu préserve une distance avec son objet, se méfie non sans contradiction de l’histoire intellectuelle de la mort, ne veut pas lui ôter son mystère, prend en compte les angoisses métaphysiques irréductibles qu’il suscite et cherche à saisir un « en-deçà » des mentalités, anthropologique, qui distingue clairement son travail de l’histoire des mentalités et de l’histoire française de la mort alors en vogue. Sa méthodologie, son usage des statistiques, la rhétorique chaunusienne et son goût du paradoxe, l’architecture de son ouvrage témoignent, plus que d’une communion avec l’historiographie de son temps, d’un dialogue avec la tradition mystique.
Chaunu, historien de la paix ?
Authors: Hippler Thomas 
Published: November 2022

La contribution analyse le traitement de la question de la paix dans l’œuvre de Pierre Chaunu. Une première partie essaie de comprendre l’absence de la thématique avant les années 1990. Une deuxième partie met la thématique de la paix en corrélation avec l’émergence des peace studies depuis les années 1950. Dans une troisième partie sont abordés les travaux de Chaunu sur la paix, depuis les deux grands colloques sur la question jusqu’à son tout dernier ouvrage, Leçons pour la paix, paru en 2006.
De la formation d’un concept à l’invention d’une tradition : les avatars de l’histoire sérielle
Authors: Müller Bertrand 
Published: November 2022

L’histoire sérielle a été une notion et une proposition centrale en histoire et dans les sciences sociales dans les années 1960. Portée par Pierre Chaunu qui avait l’ambition d’en faire le programme rénovateur et fédérateur de la discipline, l’histoire sérielle n’est pas parvenue à s’imposer et a disparu des méthodes et du vocabulaire des historiens à partir des années 1970. Cette étude se propose d’examiner, à partir d’analyses lexicométriques et en s’inspirant de l’histoire sociale des concepts, comment Pierre Chaunu a tenté, en vain, d’imposer l’histoire sérielle comme une démarche scientifique puis l’a transformée et inscrite dans l’histoire de la discipline comme une tradition inventée..
Pierre Chaunu, homo ego-historicus
Authors: Lacoue-Labarthe Isabelle 
Published: November 2022

Quand on s’intéresse à l’histoire, plus encore à l’historiographie, et particulièrement à l’ego-histoire, Pierre Chaunu est incontournable : parce que c’est un récidiviste du retour sur sa propre histoire, sous des formes et des formats divers ; parce que ces textes, qui font écho aux thèmes qui traversent les travaux de l’historien (la mémoire, la mort, la foi, le temps) et révèlent l’étroite intrication entre la conception de la vie et l’œuvre de leur auteur, interrogent la possibilité d’une réelle étanchéité entre les deux ; parce que, enfin, cette manière de revenir sur son parcours personnel s’inscrit dans un mouvement d’ensemble, dont la publication des Essais d’ego-histoire (dirigée par Pierre Nora en 1987) est, à partir des années 1980, la manifestation la plus visible et l’un des embrayeurs, tout en présentant ses propres spécificités, au premier chef desquelles un souci de vérité, tant sur soi que sur l’histoire de l’humanité.
Metodología para detectar riesgos en seguridad informática en la universidad autónoma de zacatecas basada en pruebas de penetración
Authors: González Pedro Morales , Reyes Sodel Vázquez , Barraza Santiago Villagrana , Elizondo Perla Velasco , Ramírez Carlos H. Castañeda , González Alejandro Mauricio 
Published: November 2022

El propósito de este artículo es mostrar algunas vulnerabilidades con las que se cuentan en la Universidad Autónoma de Zacatecas después de aplicar pruebas de penetración a los activos informáticos como lo son servidores, aplicaciones web y equipo de cómputo, mostrando puntos críticos que puedan comprometer el funcionamiento o información privada de la misma, exponiendo datos de alumnos, profesores y áreas administrativas. El hecho de que las universidades no contemplen los activos informáticos como un factor que pueda detener su funcionamiento resulta un gran problema, según datos de la Asociación Nacional de Universidades e instituciones de Educación Superior solo 46 universidades de 140 hacen auditorías a sus sistemas(ANUIES, 2016), por lo que esta prueba se realizó de forma interna en la universidad aplicando la metodología de penetración estándar ya que esta se adapta a los recursos y capacidades de TI con las que la universidad cuenta. Obteniendo como resultado un reporte de algunas vulnerabilidades de seguridad existentes.
Character Education in the Novel Raksasa dari Jogja and Its Implementation Design in Learning
Authors: Exsfarudin Dafit , Widayati Mukti , Sukarno Sukarno 
Published: November 2022

This research purposes at finding the values of the character in the novel “Raksasa dari Jogja” and its design for the implementation of the value of character education in the learning of high school students in class XII. The method used is descriptive qualitative with data in the form of quote words and sentences containing character values with the data source in the form of the novel “Raksasa dari Jogja” by Dwitasari. The results showed that the novel “Raksasa dari Jogja” contains five-character values in the form of religious values (firm stance & sincerity); nationalist character values (maintaining the nation's culture, & love for the homeland); independence values (courage, fighting power, hard work, resilience, & lifelong learning); gotong royong values (non-violence & help); and integrity values (responsibility and example). Implementation in learning is adjusted to the basic competencies 3.3 and 4.3 for senior high school class XII.
Muscles Cramp And Sleep Disturbances Among Hemodialysis Patients
Authors: Roy Chowdhury , Dr. Yogesh Sharma  
Published: November 2022

Muscle cramps are often experienced by the patients on hemodialysis that result in discomfort, shortened treatment times, and inadequate dialysis dose.
Up to 50% people with chronic renal failure undergoing dialysis suffer from muscle cramps, especially involving the lower limbs. The cramps can happen during dialysis or at home. The cramps in this type of patient are linked to depression, a decline in quality of life, and sleep disorders. The etiology of cramps in hemodialysis patients is not clear.
Muscle Cramping of the hands, feet, and legs is fairly common among patients on hemodialysis. Muscle Cramps are also associated with low bloodpressure. However, some Muscle cramping continues even after a normal bloodpressure. When patients are below dry weight, they also experience muscle cramps. The severe muscle cramps are experienced near the end of the dialysis and persisting for a time after dialysis is often due to dehydration. (1)
The most frequent sleep disorders seen in patients on dialysis are conditioned insomnia, excessive daytime sleepiness, obstructive or central sleep apnea, as well as restless legs syndrome (RLS) and periodic limb movement disorder. Many uremic and non-uremic factors are thought to participate in the pathogenesis of sleep disorders in these patients. The treatment of sleeping disorders includes non-pharmacological and pharmacological measures that can improve the functionality and quality of life in patients on dialysis. (2)
PRINCÍPIOS DO PROJETO CURRÍCULO: A IMPORTÂNCIA DA TECNOLOGIA NO ENSINO APRENDIZAGEM
Authors: Alves Guimarães Ueudison , Evangelista da Silva Jose , Maria Roque Silvania 
Published: November 2022

O artigo objetiva elencar sobre a importância de relacionar o processo ensino aprendizagem entre currículo e tecnologia, buscando objetivar novas metodologias interativas procurando sempre inovar o uso das tecnologias inseridas como recursos metodológicos. Tem como subsidio analisar e aplicar novas práticas metodológicas que facilitem a aprendizagem dos docentes, aplicadas na educação, que favoreçam o desenvolvimento de competências e habilidades da compreensão e do raciocínio lógico como objeto social. Justifica-se pela necessidade de que as tecnologias vêm demostrando ser uma importante aliada da socialização e educação nas novas gerações. O presente artigo tem como presuposto, desenvolver o processo de ensino aprendizagem através de elementos que foram refletidos e discutidos sobre a importância do currículo para formação das novas metodologias tecnológicas, criando condições favoráveis para o processo de ensino aprendizagem, analisando os diversos perfis do alunado em sua individualidade, sua necessidade, observando a conexão das abordagens educativas seguidas pelas tecnologias e currículos. Obteve-se como metodologia para construção do artigo pesquisas bibliográficas, internet, revistas, artigos científicos e livros que foram de grande relevância para sua construção.
Is Gender Based Violence Related to Sanitation? A Case Study of Patongo Town Council, Uganda
Authors: Roba Salad Diba 
Published: November 2022

Gender-based violence is a global problem that affects women of all races, colours and creeds. The Sustainable Development Goals also emphasise the need to pay special attention to women and girls regarding hygiene and sanitation. While lack of sanitation is not the main cause of gender-based violence, it is a significant contributor to its occurrence. Several studies have been published in the literature on violence against women in different parts of the world. Still, this study focused on Patongo Municipality, Agago District, Northern Uganda, where few studies have been conducted.
This study investigated whether gender-based violence was linked to sanitation. The study focused on sanitation practices and gender-based decision-making. It also examined gender-based violence related to sanitation, including concerns, worries and fears, and economic violence. In general, the study looked at how sanitation practices may be linked to gender-based violence. Sanitation practice is gendered and mainly revolved around excreta, pregnancy and menstrual hygiene. These practices are the result of education, culture and economic status in the household. Therefore, these sanitation practices are shaped by different norms and roles among women and men. Men and women expressed stress related to sanitation, with women expressing it more. This stress results from the location of the latrine, its accessories and the taboos around menstruation and pregnancy. This study further explores the issue of safety, privacy, protection and shame concerning sanitation practices.
Roles and responsibilities are gendered. For example, men decide on the location and financing of the latrine, while women are responsible for the daily maintenance of the latrine. Due to their education and socioeconomic status, women sometimes decide on the latrine's location.The community had different perceptions of gender-based violence. For them, gender-based violence referred only to sexual and physical violence. However, the study found various forms of gender-based violence in the community, including Sexual, physical, emotional and economic violence. Although these forms existed in the community, the study concluded that gender-based violence was not related to sanitation.
Optimization of Sequential Microwave-Ultrasonic-Assisted Extraction of Flavonoid Compounds from Moringa oleifera
Authors: Prasetyaningrum Aji , Widayat Widayat , Jos Bakti , Ratnawati Ratnawati , Riyanto Teguh , Prinanda Gian Restu , Le Monde Brilliant Umara , Susanto Evan Eduard 
Published: November 2022

Flavonoid are bioactive compounds that can be found in moringa leaves. Extraction of bioactive compounds using conventional method requires a long time and low extract yields. This study was aimed to determine the optimum process conditions of sequential microwave-ultrasonic-assisted extraction (MUAE) of total flavonoids (TF) from moringa. The response surface methodology (RSM) with Box-Behnken design (BBD) was employed to determine the optimum operating conditions of MUAE among the set of variables: Time (10 - 30 min), temperature (40 - 60 °C), and solvent concentration (60 - 80%). Furthermore, the flavonoids content was determined using high-performance liquid chromatography (HPLC) and the antioxidant activity was analyzed using the DPPH scavenging method. The RSM optimization showed that the predicted optimum total flavonoids content was 3.25 quercetin equivalent (QE) mg/g, achieved under operating conditions at a temperature of 49.76 °C, extraction time 20.68 min and solvent concentration of 71.16 %. These optimum operating conditions were validated, resulting in an average error of 0.546 %. The MS/HPLC results showed that the content of quercetin and myricetin were 0.167 and 2.89 g/ 100 mL, respectively. Moringa extraction product has a strong antioxidant activity with IC50 of 74.58 - 74.62 µg/mL.
HIGHLIGHTS

For the first time, sequential microwave ultrasonic extraction of flavonoid components from moringa was conducted
Data from the RSM method’s operating conditions optimization can be used to support the design of industrial-scale machines for extracting flavonoids
In comparison to other extraction techniques, the flavonoid content obtained with sequential microwave-ultrasonic was the highest at 3.25 mg QE/g
It was discovered that the antioxidant generated using sequential microwave-ultrasonic technology had a greater inhibitory power than the maceration approach, with an IC50 of 74.58

GRAPHICAL ABSTRACT
Population Ecology and Habitat use of the Sea Slug Elysia pusilla (Bergh, 1872) (Sacoglossa) in A Tropical Halimeda macroloba Decaisne Meadow
Authors: Nakpan Apisara , Mayakun Jaruwan , Wangkulangkul Kringpaka 
Published: November 2022

Relationship between abundance of specialist marine herbivores and their food sources is poorly known because these herbivores are relatively rare in marine systems. The relationship between the cryptic sea slug Elysia pusilla (Bergh, 1872) and its host alga, Halimeda macroloba Decaisne, was evaluated in terms of spatial association and habitat utilization in a tropical algal meadow in southern Thailand that exclusively comprised of H. macroloba. The density of H. macroloba and of E. pusilla egg masses varied temporally throughout the sampling period, but temporal variation was not detected in the density of E. pusilla individuals, which was generally low with a maximum of 4 individuals per 400 cm2. Analysis suggests that the occurrence of the slug and its egg masses might be determined by the availability of the algal host. The slug was more likely to be observed in dense patches of algae that which offered a large total algal surface area. Occurrence of the slug was also higher when the algae were abundant. The numbers of slugs, egg masses and grazing marks were higher on mature thalli, which have larger surface areas than younger thalli. Egg masses and grazing marks were observed more often on segments at terminal positions on thalli. According to previous works, these segments contain low levels of accumulated calcium carbonate and high levels of secondary metabolites, which are sequestered by the slug and used to deter predators. The findings provide an insight into the life history of E. pusilla and variations in a natural population which that were previously little known.
HIGHLIGHTS

The relationship between the cryptic sea slug Elysia pusilla (Bergh, 1872) and its host alga, Halimeda macroloba Decaisne, was evaluated in terms of spatial association and habitat utilization in a tropical algal meadow in southern Thailand
The slug pusilla was more likely to be observed in dense patches of its algal host H. macroloba
Occurrence of the slug was also higher when the algae were abundant
The numbers of slugs, egg masses and grazing marks were higher on mature thalli
Egg masses and grazing marks were observed more often on segments at terminal positions on thalli

GRAPHICAL ABSTRACT
caso de los jesuitas dos años después
Authors: Tojeira José María 
Published: November 2022

Conferencia pronunciada el 13 de noviembre de 1991, en el auditorio de la UCA, durante las celebraciones del segundo aniversario. El texto tiene tres partes. En la primera, se hace una interpretación del martirio de los jesuitas de la UCA y de sus dos colaboradoras. En la segunda, se interpreta la vista pública y el veredicto y, en la última, se dan razones por las cuales se sostiene la existencia de autores intelectuales.
ECA Estudios Centroamericanos, Vol. 46, No. 517-518, 1991: 1033-1044.
Pegvaliase (Palynziq)
Authors: CADTH  
Published: November 2022

CADTH recommends that Palynziq should be reimbursed by public drug plans for the treatment of patients with phenylketonuria (PKU) aged 16 years and older who have inadequate blood phenylalanine control (blood phenylalanine levels greater than 600 µmol/L) on existing management if certain conditions are met.
Palynziq should only be covered to treat patients with PKU aged 16 years and older.
Palynziq should only be reimbursed for patients who demonstrate and maintain a response to treatment (blood phenylalanine levels less than 600 µmol/L), if the drug is prescribed by a clinician with expertise in treating genetic and metabolic disorders, and if the cost of Palynziq is reduced.
Asciminib (Scemblix)
Authors: CADTH  
Published: November 2022

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses asciminib (Scemblix), 80 mg q.d. or 40 mg b.i.d. oral tablets.
Indication: For the treatment of adult patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase previously treated with 2 or more tyrosine kinase inhibitors.
Championship Living in a Computer Age
Authors: Byrne Richard 
Published: November 2022

We live in the computer age; I’m absolutely sure of it. Earlier in this series, I hedged my bets and said, “Is it really real, and do you think so, and it’s up to you,” and so forth. I’m here to tell you now, we live in a computer age.
Furthermore, we live in an age of breakthrough. There are lightening leaps, and quantum jumps being made in every aspect of human life right now. I am sure that you can learn to embrace this new momentum, in order to break through any barriers in your own life. You can find those old anchors to your past, you can let go of them, and you can break through to a new unanticipated plateau.
Karakteristik Nanopartikel Ekstrak Etanol 70% Daun Jarak Pagar (Jatropha Curcas L.) dengan Metode Gelasi Ionik
Authors: Fitri Dewi Rahma , Syafei Dedri , Sari Cahya Purnama 
Published: November 2022

Aplikasi teknologi nano dalam bidang farmasi mempunyai berbagai keunggulan antara lain dapat meningkatkan kelarutan senyawa, mengurangi dosis pengobatan dan meningkatkan absorbsi. Nanopartikel yang dibuat dari reaksi sambung silang antara kitosan dengan NaTPP memiliki efisieni penjerapan yang tinggi, kandungan zat aktif tinggi serta kestabilan yang baik. Tanaman jarak pagar (Jatropha curcas L.) tidak termasuk ke dalam tanaman pangan, sehingga pemanfaatannya sebagai bahan baku obat diharapkan tidak mengganggu stabilitas harga pangan maka perlu dikembangkan. Penelitian ini bertujuan untuk mengetahui karakteristik nanopartikel ekstrak etanol 70% daun jarak pagar dengan kosentrasi kitosan 0,2% dan NaTPP 0,1% dengan beberapa perbandingan volume kitosan dan NaTPP 3:1, 2:1, 5:1 menggunakan metode gelasi ionic. Nanopartikel dibuat dengan 3 perbandingan volume larutan masing-masing formula 3:1, 2:1, 5:1. Berdasarkan hasil karakterisasi nanopartikel ekstrak etanol 70% daun jarak pagar pada parameter uji ukuran partikel, zeta potensial, dan morfologi partikel didapatkan perbandingan optimal pada formula 2:1 mempunyai rata-rata ukuran partikel 284,1 nm, indeks polidispersitas 0,460, nilai zeta potensial +34,5 mV dan bentuk morfologi dengan bentuk agregat longgar dan permukaan yang tidak rata.
Aktivitas Antioksidan dan Skrining Fitokimia dari Ekstrak Daun Matoa Pometia pinnata
Authors: Islami Deri , Anggraini Lovera , Wardaniati Isna 
Published: November 2022

Senyawa yang memiliki aktivitas antioksidan Antioksidan dapat digunakan menghilangkan, mencegah pembentukan radikal bebas di dalam tubuh. Senyawa yang bersifat sebagai antioksidan ini bekerja dengan cara menghambat radikal bebas untuk menghentikan reaksi oksidatif molekul-molekul yang tidak stabil di dalam tubuh dan menyerang makromolekul termasuk protein, DNA, dan lipid yang menyebabkan kerusakan pada sel/jaringan. Tanaman Matoa (Pometia pinnata) merupakan jenis tanaman dari famili Sapindaceae yang telah digunakan oleh masyarakat sebagai obat tradisional. Pada penelitian ini telah dilakukan uji aktivitas antioksidan dan skrining fitokimia dari ekstrak n-heksana, ekstrak etil asetat serta ekstrak etanol daun matoa. Aktivitas antioksidan diuji menggunakan metode DPPH radikal bebas. Hasil uji aktivitas antioksidan menunjukkan bahwa ekstrak etanol dari daun matoa memiliki aktivitas yang tinggi dengan IC50 1,403 μg/mL , namun ekstrak etil asetat dan n-heksana juga juga masih dikatakan aktif dalam uji DPPH dengan nilai IC50 masing-masing sebesar 261,07 μg/mL dan 306,49 μg/mL. Pada Pengujian Skrining fitokimia masing-masing ekstrah menunjukan bahwa daun matoa ini mengandung senyawa metabolit sekunder golongan flavonoid, Steroid, Tanin dan Saponin. Temuan keseluruhan menunjukkan potensi ekstrak etanol dan etil asetat daun matoa untuk penelitian lanjutan sebagai obat herbal karena hasil menunjukkan aktivitas antioksidan yang baik.
Isolasi dan Pengujian Aktivitas Antibakteri Minyak Essensial Daun Torbangun (Plectranthus Amboinicus (Lour.) Spreng terhadap Bakteri Staphylococcus aureus
Authors: Hilmarni Hilmarni , Rosi Devahimer Harsep , Kusuma Ariya Eka 
Published: November 2022

Plectranthus amboinicus merupakan tanaman yang telah lama digunakan sebagai obat dan makanan. Tumbuhan ini mengandung metabolit sekunder yang berhubungan dengan pemanfaatannya untuk pengobatan seperti tanin, saponin, flavonoid, glikosida steroid. Selain itu, kandungan daun dan batang Plectranthus amboinicus diantaranya adalah minyak atsiri. Penelitian ini bertujuan untuk mengetahui pada konsentrasi minyak essensial daun Torbangun yang dapat menghambat pertumbuhan bakteri Staphylococcus aureus. Aktivitas antibakteri ditentukan dengan metode uji difusi agar. Konsentrasi minyak essensial Daun Plectranthus amboinicus yang digunakan adalah 1%,2%, 4%,6% dan 8%. Hasil penelitian menunjukan minyak essensial Torbangun dengan konsentrasi 6 dan 8 % menunjukan aktifitas sebagai antibakteri yang sangat kuat dengan diameter hambat 20,23 dan 22,83 mm. Hasil ini menguatkan penggunaan Plectranthus amboinicus dapat digunakan untuk pengobatan infeksi yang disebabkan oleh Staphylococcus aureus.