bluuebunny/crossref_metadata_2025_split huggingface dataset:
A piece of a puzzle—Patient and psychologist experiences of the Affect School as additional treatment in a Swedish eating disorder unit
Authors: Petersson Suzanne , Wåhlin Ingrid 
Published: July 2022

Background
Emotion dysregulation has been shown to be a transdiagnostic characteristic of eating disorders. The Affect School aims to enhance emotional awareness and the ability to perceive and express emotions. This study was conducted as part of an RCT where patients with various eating disorders were randomised to participation in the Affect School as a supplement to treatment.

Aim
To explore Affect School participants’ and leaders’ experiences of the Affect school at an Eating Disorder outpatient unit in Sweden.

Method
Nine patients with eating disorder diagnoses and three Affect School leaders at an eating disorder outpatient clinic in Sweden were interviewed for their experiences of the intervention. The interviews were analysed with Thematic Analysis.

Result
Eight themes were revealed at the analysis, five from the participants: “Worries about group participation”, “Not alone anymore and gaining new insights about oneself”, “Shared stories can also be painful”, “Relationships outside the Affect School as a foundation for affective work”, and “A change is coming”, and three from the leaders:”Affect awareness is important in eating disorders”, “Group meetings create opportunities and challenges”, and “The Affect School setup needs more customisation”.

Conclusion
The results suggested that the Affect School provided an acceptance for experiencing all sorts of affects. Both leaders and participants considered working with affects necessary, although participants reported no changes in their life situation or condition after the intervention but considered the intervention as part of a process with gradual results. Being part of a group and sharing experiences was experienced as positive by participants and leaders, but the model could be further developed to better adapt to patients with an eating disorder.
Survival outcomes of surgery for retroperitoneal sarcomas: A systematic review and meta-analysis
Authors: Guo Qiang , Zhao Jichun , Du Xiaojiong , Huang Bin 
Published: July 2022

BackgroundDefinitive evidence to guide clinical practice on the principles of surgery for retroperitoneal sarcomas (RPSs) is still lacking. This study aims to summarise the available evidence to assess the relative benefits and disadvantages of an aggressive surgical approach with contiguous organ resection in patients with RPS, the association between surgical resection margins and survival outcomes, and the role of surgery in recurrent RPS.MethodsWe searched PubMed, the Cochrane Library, and EMBASE for relevant randomised trials and observational studies published from inception up to May 1, 2021. Prospective or retrospective studies, published in the English language, providing outcome data with surgical treatment in patients with RPS were selected. The primary outcome was overall survival (OS).FindingsIn total, 47 articles were analysed. There were no significant differences in the rates of OS (HR: 0.93; 95% CI: 0.83–1.03;P= 0.574) and recurrence-free survival (HR: 1.00; 95% CI: 0.74–1.27;P= 0.945) between the extended resection group and the tumour resection alone group. Organ resection did not increase postoperative mortality (OR: 1.00; 95% CI: 0.55–1.81;P= 0.997) but had a relatively higher complication rate (OR: 2.24, 95% CI: 0.94–5.34;P= 0.068). OS was higher in R0 than in R1 resection (HR: 1.34; 95% CI: 1.23–1.44;P< 0.001) and in R1 resection than in R2 resection (HR: 1.86; 95% CI: 1.35–2.36;P< 0.001). OS was also higher in R2 resection than in no surgery (HR: 1.26; 95% CI: 1.07–1.45;P< 0.001), however, subgroup analysis showed that the pooled HR in the trials reporting primary RPS was similar between the two groups (HR, 1.14; 95% CI, 0.87–1.42;P= 0.42). Surgical treatment achieves a significantly higher OS rate than does conservative treatment (HR: 2.42; 95% CI: 1.21–3.64;P< 0.001) for recurrent RPS.ConclusionsFor primary RPS, curative-intent en bloc resection should be aimed, and adjacent organs with evidence of direct invasion must be resected to avoid R2 resection. For recurrent RPS, surgical resection should be considered as a priority. Incomplete resection remains to have a survival benefit in select patients with unresectable recurrent RPS.
Impact of prenatal maternal psychological distress on fetal biometric parameters in household air pollution-exposed Nigerian women
Authors: Deji-Abiodun Oluwafunmilade , Adedokun Babatunde , Alexander Donee , Dutta Anindita , Ibigbami Tope , Olamijulo John , Adepoju Dayo , Adekunle Samuel , Ojengbede Oladosu , Olopade Christopher O. 
Published: July 2022

Rationale
Studies identify prenatal household air pollution (HAP) exposure and maternal psychological distress (PMPD) as independent factors contributing to gestational ill-health and adverse birth outcomes.

Objective
We investigated the impact of PMPD on fetal biometric parameters (FBP) in HAP-exposed pregnant Nigerian women.

Methods
The randomized controlled trial (RCT; ClinicalTrials.gov NCT02394574) investigated effects of HAP exposure in pregnant Nigerian women (n = 324), who customarily cooked with polluting fuels (firewood or kerosene). Half of the women (intervention group) were given CleanCook ethanol stoves to use for 156 days during the study. Once a month, all women were administered an abridged version of the SF-12v2TM health-related quality of life questionnaire to assess psychological distress. Using mixed effects linear regression models, adjusted for relevant covariates, we analyzed associations between the women’s exposure to PM2·5 (particulate matter with an aerodynamic diameter<2·5 microns) from HAP, their PMPD scores, and FBP (ultrasound estimated fetal weight [UEFW], head circumference [HC], abdominal circumference [AC], femur length [FL], biparietal diameter [BPD], estimated gestational age [GA] and intrauterine growth restriction [IUGR]), and birth anthropometric measures (birth weight [BW] and birth length [BL]).

Results
PMPD negatively impacted UEFW, HC, FL, BPD and BL (p<0·05). Controls (kerosene/firewood users) experienced significantly higher PMPD compared with ethanol-stove users (p<0·05). The mediation analysis revealed that the proportion of the outcome (fetal biometrics, birth anthropometrics, IUGR and GA), which can be explained via PMPD by groups (intervention vs. control) after adjusting for confounding variables was 6·2% (0·062). No significant correlation was observed between levels of PM2.5 exposure and PMPD scores.

Conclusions
PMPD was an independent mediator of adverse fetal biometric parameters in pregnant women, who were exposed to HAP from burning of firewood/kerosene. Formulating preventative measures to alleviate maternal distress during pregnancy and reducing exposure to HAP is important from public health perspectives.
Comparison of short-term clinical outcomes between low-dose prasugrel and clopidogrel as part of triple antithrombotic therapy in patients requiring oral anticoagulant therapy and percutaneous coronary intervention
Authors: Kitahara Hideki , Tateishi Kazuya , Shiko Yuki , Inaba Yusuke , Kobayashi Yoshio , Inoue Takahiro 
Published: July 2022

Background
Triple antithrombotic therapy, including dual antiplatelet therapy and oral anticoagulant (OAC), is recommended for a short-term period after percutaneous coronary intervention (PCI) in patients requiring anticoagulation therapy. The purpose of this study was to compare in-hospital clinical outcomes between low-dose prasugrel (3.75 mg/day) and clopidogrel, as part of triple antithrombotic therapy, using a large database in Japan.

Methods
Patients with ischemic heart disease who underwent PCI between January 2015 and December 2019, and were prescribed triple therapy with aspirin, a P2Y12 inhibitor (clopidogrel or low-dose prasugrel), and OAC (direct oral anticoagulant: DOAC or vitamin K antagonist: VKA), were selected from the Diagnosis Procedure Combination database. The primary outcome was in-hospital mortality. The secondary outcomes were myocardial infarction, ischemic stroke, bleeding stroke, gastrointestinal bleeding, and blood transfusion.

Results
Overall, 5,777 patients were eligible in this analysis. The patients were divided into 4 subgroups according to the type of P2Y12 inhibitor and OAC: clopidogrel/DOAC (n = 1,628), clopidogrel/VKA (n = 1,334), prasugrel/DOAC (n = 1,607), and prasugrel/VKA (n = 1,208). There was no significant difference in the incidence of death and gastrointestinal bleeding among the 4 subgroups. The prasugrel/DOAC group had significantly lower incidence of MI (OR 0.566, 95% CI 0.348–0.921). The incidence of ischemic stroke was significantly lower in the prasugrel/DOAC group (OR 0.701, 95% CI 0.502–0.979), and significantly higher in the clopidogrel/VKA group (OR 1.680, 95% CI 1.273–2.216). Need for blood transfusion was less frequent in the prasugrel/DOAC group (OR 0.729, 95% CI 0.598–0.890), and more frequent in both the clopidogrel/VKA group (OR 1.424, 95% CI 1.187–1.708) and the prasugrel/VKA group (OR 1.633, 95% CI 1.367–1.950).

Conclusions
Combination of low-dose prasugrel and DOAC was associated with lower incidence of MI, ischemic stroke, and blood transfusion. Low-dose prasugrel may be feasible as part of triple therapy in patients undergoing PCI.
Gender and socio-economic stratification of ultra-processed and deep-fried food consumption among rural adolescents: A cross-sectional study from Bangladesh
Authors: Islam Mohammad Redwanul , Rahman Syed Moshfiqur , Rahman Md. Monjur , Pervin Jesmin , Rahman Anisur , Ekström Eva-Charlotte 
Published: July 2022

BackgroundAlthough consumption of ultra-processed and deep-fried foods among adolescents is a global health concern, little is known about its gender and socio-economic stratification in rural settings of low- and middle-income countries. We, thus, aimed to describe ultra-processed and deep-fried food consumption among rural adolescents by gender and socio-economic factors, and to explore their relative importance in shaping consumption.MethodsThis cross-sectional study drew on data from a household survey in Matlab, a rural sub-district in Bangladesh. The analytic sample comprised 2463 adolescents. We assessed consumption of four ultra-processed food groups: ready-to-eat or “instant” foods; confectionery, sweets and similar packaged products; savory snacks; sugar-sweetened beverage; and of deep-fried foods with a 24-hour, qualitative recall. Asset scores were constructed. Proportion of consumption was calculated and compared by gender and household wealth. Logistic regression models were fitted to isolate socio-demographic variables associated with consumption.ResultsApproximately 83% (81.5–84.4) adolescents consumed at least one ultra-processed or deep-fried item. Confectioneries were the most consumed (53.5%), whereas sugar-sweetened beverage was the least consumed (12%) group. Boys had greater odds of consumption than girls for all food groups. The association was strongest for sugar-sweetened beverage (adjusted odds ratio = 2.57; 95% CI: 1.97, 3.37), followed by deep-fried foods (adjusted odds ratio = 1.96; 95% CI: 1.66, 2.32) and ready-to-eat foods (adjusted odds ratio = 1.85; 95% CI: 1.45, 2.38). Belonging to the richest households was associated with ready-to-eat food consumption (adjusted odds ratio = 1.55; 95% CI: 1.12, 2.16). Adolescents with higher educational attainment had lower odds of consuming sugar-sweetened beverage (adjusted odds ratio = 0.73; 95% CI: 0.54, 0.98).ConclusionConsumption of packaged confectioneries, savory snacks, and deep-fried foods appeared common, while SSB consumption was relatively low. Role of gender was pre-eminent as consumption was more likely among boys across the food groups. This may disproportionately expose them to the risk of diet-related non-communicable diseases.
ZAKβ is activated by cellular compression and mediates contraction‐induced MAP kinase signaling in skeletal muscle
Authors: Nordgaard Cathrine , Vind Anna Constance , Stonadge Amy , Kjøbsted Rasmus , Snieckute Goda , Antas Pedro , Blasius Melanie , Reinert Marie Sofie , Del Val Ana Martinez , Bekker‐Jensen Dorte Breinholdt , Haahr Peter , Miroshnikova Yekaterina A , Mazouzi Abdelghani , Falk Sarah , Perrier‐Groult Emeline , Tiedje Christopher , Li Xiang , Jakobsen Jens Rithamer , Jørgensen Nicolas Oldenburg , Wojtaszewski Jørgen FP , Mallein‐Gerin Frederic , Andersen Jesper Løvind , Pennisi Cristian Pablo , Clemmensen Christoffer , Kassem Moustapha , Jafari Abbas , Brummelkamp Thijn , Li Vivian SW , Wickström Sara A , Olsen Jesper Velgaard , Blanco Gonzalo , Bekker‐Jensen Simon 
Published: July 2022

AbstractMechanical inputs give rise to p38 and JNK activation, which mediate adaptive physiological responses in various tissues. In skeletal muscle, contraction‐induced p38 and JNK signaling ensure adaptation to exercise, muscle repair, and hypertrophy. However, the mechanisms by which muscle fibers sense mechanical load to activate this signaling have remained elusive. Here, we show that the upstream MAP3K ZAKβ is activated by cellular compression induced by osmotic shock and cyclic compression in vitro, and muscle contraction in vivo. This function relies on ZAKβ's ability to recognize stress fibers in cells and Z‐discs in muscle fibers when mechanically perturbed. Consequently, ZAK‐deficient mice present with skeletal muscle defects characterized by fibers with centralized nuclei and progressive adaptation towards a slower myosin profile. Our results highlight how cells in general respond to mechanical compressive load and how mechanical forces generated during muscle contraction are translated into MAP kinase signaling.
Pharmacoeconomic study of the treatment of arterial hypertension in children and adolescents using cost-of-illness analysis
Authors: Mikhaylova O. S. , Krikova A. V. 
Published: July 2022

Background. The cost-of-illness (COI) analysis allows to estimate and plan costs for calculations between the subjects of the health care system and medical insurance organizations. The primary morbidity of the population with diseases of the circulatory system increased from 4,784 thousand people in 2018 to 5,136 thousand in 2019. A growth in the number of cases resulted in an increase in the demand for drugs for the treatment of cardiovascular diseases.Objective: to perform a pharmacoeconomic study of the treatment of arterial hypertension in children and adolescents by COI-analysis.Material and methods. The source of information for COI-analysis was the real clinical practice – medical records of sick children and adolescents. A pharmacoeconomic study using COI-analysis was carried out at the inpatient and outpatient stages of care and included the calculation of direct medical costs (the costs of laboratory, instrumental medical services, non-drug and drug antihypertensive therapy). The study included 102 children diagnosed with arterial hypertension. The average stay of patients in the hospital was 10 (10.4±0.35) bed-days and treatment on an outpatient basis varied from 3 months to 1 year.Results. The leading place in the structure of costs for antihypertensive therapy is occupied by the beta-blockers pharmacological group (35%). The total cost of arterial hypertension in children and adolescents in inpatient and outpatient settings was 4,459.00 and 29,638.90 rubles, respectively.Conclusion. The COI-analysis of arterial hypertension confirms the need for timely diagnosis and treatment and preventive measures for high blood pressure in children and adolescents to reduce the development of risk factors for such serious cardiovascular complications as stroke and myocardial infarction in adulthood, the treatment of which requires large cash costs.
Experience of implementing a value-based approach in oncodermatology
Authors: Zuenkova Yu. A. , Kicha D. I. , Izyurov L. N. 
Published: July 2022

Objective: implementation of value-based approach and development of adherence to treatment in patients with non-melanoma cancer.Material and methods. The observational, single-arm, prospective, long-term single-center study of the quality of life and patients’ experience was performed. It included 42 patients aged from 42 to 82 years. Validated questionnaires were used: Patient-Reported Outcome Measures (PROMs) (as a decision support tool), Patient-Reported Experience Measures (PREMs) (3 months after treatment to assess the patient's experience).Results. Mean concern about appearance was 43.5 points (Rasch psychometric model). Younger patients (r=–0.398, p=0.009) and female patients (r=–0.475, p=0.001) were more concerned about appearance. In 10 cases (24%), the involvement was estimated as 4 points, in 18 cases (43%), it was 3 points, in 14 cases (33%), it was 2 points. Older patients were less involved in the choice of treatment method (r=–0633, p<0.001). The level of satisfaction with communications was more than 50 points. The use of a patient-oriented algorithm of communication has a positive effect on a patient's experience.Conclusion. The heads of oncological care are recommended to evaluate the patient's experience on a regular basis, create conditions for patients to choose treatment methods according to their individual needs, analyze the outcomes obtained by the introduction of validated questionnaires on the appropriate nosological profile and take these results into account in treatment. Further studies of the degree of influence of different factors on a patient’s choice of treatment method are needed, as well as conducting studies among other groups of patients with non-melanoma skin cancer (located in other parts of the body, larger than 2 cm).
Meningkatkan Keterampilan Menyimak Cerita Melalui Model Paired Storytelling Berbantuan Media Youtube
Authors: Velinda Intan , Aeni Ani Nur , Iswara Prana Dwija 
Published: July 2022

Penelitian ini bertujuan untuk mengetahui peningkatan keterampilan menyimak cerita melalui penggunaan model paired storytelling dengan bantuan media youtube. Kegiatan penelitian ini dilakukan dengan mengikuti tahapan metodologi penelitian tindak kelas dengan penyajian deskriptif kualitatif, sehingga proses pegumpulan data dilakukan mengunakan instrumen berupa tes dan nontes. Subjek dalam penelitian ini adalah siswa kelas dan guru kelas VI yang berlokasi di SDN Panyingkiran II Sumedang, Jawa Barat. Data yang diperoleh dianalis secara deskriptif kuantitatif. Data hasil analisis kemudian di interpretasi berdasarkan tujuan dari peneliti. Sehingga di ketahui bahwa penggunaan model Paired storytelling dengan bantuan media youtube dapat meningkatkan keterampilan menyimak cerita siswa kelas VI di SDN Panyingkiran II Sumedang, Jawa Barat.
La corriente pedagógica cooperaria
Authors: Yorg José Alberto , Ramírez Zarza Ana María 
Published: July 2022

El presente trabajo constituye el resultado de una reflexión extendida y estudio de lo que entendemos como significante del cooperativismo en la educación desde el pensamiento de Robert Owen en esa esfera, poniéndolo en tensión con los modelos educativos actuales. Las sucesivas reformas educativas implementadas en el mundo entero, con el eufemismo de «educación de calidad» y otras denominaciones fracasan una detrás de las otras. Por otro lado, hay una necesidad también de publicar este segundo trabajo sobre esta temática construida sobre la base de aquel trabajo denominado «La génesis de la Pedagogía Cooperaria», replicando puntos substanciales de él, porque es necesario insistir en que no es posible ser fiel al ideario cooperativo implementando cursos, conferencias y seminarios de educación cooperativa bajo los lineamientos pedagógicos liberales absorbidos en los institutos de formación docente. Hemos recibido muchas críticas y algunos consejos en nuestra persistencia de que el cooperativismo posee su pedagogía sui génesis. Nos interrogamos cómo se espera que la educación cooperativa, imbuida de pedagogía liberal —sea por cuestiones de formatos, o por una incorrecta concepción del cooperativismo— y también, a resulta de la crisis educativa, ayude a transformar o cuanto menos indique cambios que demandan nuestras sociedades.
Recibido: 19 septiembre 2021Aceptado: 23 marzo 2022
El Arbitraje Cooperativo en Euskadi. Propuestas de mejora para dotar al SVAC-BITARTU de una mayor garantía
Authors: Sanz García Asier 
Published: July 2022

En la actual situación Social y Económica generada por la pandemia de la COVID-19, tenemos que destacar el papel primordial que han adoptado las Sociedades Cooperativas en nuestra Sociedad. No obstante, tampoco son ajenas a los conflictos que suelen suscitarse entre las mismas y sus socios y viceversa. Por ello, en el caso de que las materias de los conflictos sean de libre disposición entre las partes, podrían solucionarse por medios extrajudiciales, los cuales han ganado un especial protagonismo en nuestra sociedad. De esta manera, este autor estima oportuno realizar una serie de propuestas de mejora respecto al Procedimiento Arbitral del Consejo Superior de Cooperativas de Euskadi (SVAC-BITARTU) para dotarlo de una mayor garantía de la que actualidad posee.
Recibido: 04 noviembre 2021Aceptado: 20 mayo 2022
Urbi et orbi: o cooperativismo como expressão prática do princípio da subsidiariedade
Authors: Krueger Guilherme , Ribeiro Pedro 
Published: July 2022

O magistério eclesiástico sobre a doutrina social da Igreja Católica Apostólica Romana relaciona a transcendência salvífica da cooperação ao princípio da subsidiariedade que pondera o grau e o modo de intervenção do Estado em vista do bem comum. Esse magistério encontra no cooperativismo uma forma de integração entre a ciência e a fé numa razão prática para as comunidades economicamente organizadas. O principio da subsidiariedade não encontra positivação em um dispositivo específico da Constituição Federal do Brasil. Mas, a contemplação ali da liberdade de constituição de cooperativas como garantia fundamental da cidadania cominado com o comando ao Estado de estímulo e promoção ao cooperativismo na ordem econômica constitucional são eloquentes pelos quais se pode inferir que o Direito brasileiro reconhece nas cooperativas a excelência que resta expressa na teologia cristã quanto ao caráter radicalmente comunitário da vivência feliz em sociedade. Donde se pode concluir que o princípio da subsidiariedade está incorporado de modo implícito ao corpo do Estado Democrático de Direito no Brasil
Recibido: 23 noviembre 2021Aceptado: 19 abril 2022
Workers’ cooperatives as a tool to promote labour market inclusion for migrants
Authors: Arrieta Idiakez Francisco Javier , López Rodríguez Josune , Martínez Etxeberria Gonzalo 
Published: July 2022

The aim of this study is to identify the ways in which worker cooperatives can promote labour market inclusion for migrants. To that end, first, we will refer to the legal literature that supports the suitability of the cooperative formula in order to achieve the aforementioned purpose. By means of this analysis, our main contributions will be the following: the description of the channels that worker cooperatives offer to regularise the entrance and the work of migrants in the European Union, avoiding this way different phenomena, such as, smuggling of migrants, human tracking or informal work; the description of the contribution of worker cooperatives to the integration process of migrants, paying special attention to their training-learning and their potential, the different initiatives of social entrepreneurship and the creation of networks and associations with local communities that favour the assistance, counsel and social cohesion; and the study of the ways in which Public Administrations can promote workers cooperatives taking into account their contribution to favour decent work for migrants.
Received: 22 November 2021Accepted: 10 April 2022