bluuebunny/crossref_metadata_2025_split huggingface dataset:
DEED: A Multimodel Dataset for Dream Emotion Classification
Authors: Zheng Lei , Zhou Di , Zhang Meng , Liu Qiao , Cai Yongchun , Yang Yang , Ma Pengcheng , Wang Xiaoan , Luo Junwen 
Published: October 2022

Abstract
Although the number of research on exploring the brain neural mechanisms has been increasing dramatically, the dream-related aspects - especially dream emotion – are not yet well understood. This status is exacerbated by the lack of sufficient EEG dream data with emotion labels. To accelerate research on decoding the neural mechanisms of dream emotions, we released the Dream Emotion Evaluation Dataset (DEED), which contains multimodel dream-related information. In addition to multiple emotional personal trait assessment questionnaires, the neural data was collected from 38 participants over 82 nights by polysomnography (PSG). After each rapid eye movement (REM) awakening, participants reported their dream contents and affective states. Using the DEED, we implemented the first dream emotion classification algorithms, which are support vector machine (SVM), convolutional neural networks (CNN) and convolutional neural networks (CNN). Meanwhile, power spectral density (PSD), differential entropy (DE), multi-frequency band common spatial pattern (MCSP) is employed for feature extraction. Our results indicated that the combination of MCSP and SVM has the highest accuracy (83.6%). To summarize, the open-source DEED provides valuable data for addressing the neural mechanism of the dream, and several algorithms have verified its credibility in this work. We encourage researchers to use it to investigate the relationship between dreams and neural activities and develop the AI algorithms with biological intelligence.
Alteration of immunoproteasome mRNA in PBMCs of patients with Parkinson’s disease
Authors: Kim Young Eun , NGUYEN HUU DAT , Nguyen Linh Thi Nhat , Kwak In Hee , Lee Yoon Kyoung , ma Hyeo-Il 
Published: October 2022

Abstract
Background
Immunoproteasome, a part of ubiquitin–proteasome system, is involved in protein degradation and immune response. However, the relationship between immunoproteasome and Parkinson’s disease (PD) was not evaluated clearly. We hypothesized that the shift of immunoproteasome attributes to PD due to its role in immune system and protein homeostasis.
Objective
To determine whether immunoproteasome mRNA in peripheral blood mononuclear cells is expressed differently between patients with PD and healthy controls and to test its value as a biomarker of PD
Methods
Blood samples were collected from 19 healthy controls and 40 patients with PD of comparable ages. Peripheral blood mononuclear cells were isolated and used to measure by RT-qPCR the mRNA levels of three catalytic subunits of immunoproteasome, namely, PSMB8, PSMB9, and PSMB10.
Results
The levels PSMB9 and PSMB10 mRNA were not different between the PD group and healthy control group, whereas the PSMB8 mRNA in PD group significantly increased. The ratio of PSMB10 and PSMB8 (PSMB10/8) best reflected significant difference between the PD group and healthy control group (p = 0.002). This ratio can discriminate all PD, mild PD (Hoehn and Yahr ≤ 2.5), and drug-naive PD from healthy controls. We found correlation between the PSMB10/8 ratio with the UPDRS total and Part III score in the mild PD subgroup and drug-naive PD subgroups
Conclusion
The expression of PSMB8 mRNA increased in PD, and the PSMB10/8 ratio can differentiate Parkinson’s disease from healthy controls.
Interplay of diruthenium catalyst in controlling enantioselective propargylic substitution reactions with visible light-generated alkyl radicals
Authors: Zhang Yulin , Tanabe Yoshiaki , Kuriyama Shogo , Sakata Ken , Nishibayashi Yoshiaki 
Published: October 2022

Abstract
Transition metal-catalyzed enantioselective free radical substitution reactions have recently attracted attention as convenient and important building tools in synthetic chemistry, although construction of stereogenic carbon centers at the propargylic position of propargylic alcohols by reactions with free radicals remains unchallenged. Here we present a strategy to control enantioselective propargylic substitution reactions with alkyl radicals under photoredox conditions by applying dual photoredox and diruthenium catalytic system, where the photoredox catalyst generates alkyl radicals from 4-alkyl-1,4-dihydropyridines, and the diruthenium core with a chiral ligand traps propargylic alcohols and alkyl radicals to guide enantioselective alkylation at the propargylic position, leading to high yields of propargylic alkylated products containing a quaternary stereogenic carbon center at the propargylic position with a high enantioselectivity.
A Preliminary Assessment of the GSMaP Version 08 Products over Indonesian Maritime Continent against Gauge Data
Authors: Ramadhan Ravidho , Marzuki Marzuki , Yusnaini Helmi , Muharsyah Robi , Tangang Fredolin , Vonnisa Mutya , Harmadi Harmadi 
Published: October 2022

Abstract
This study is a preliminary assessment of the latest version of the Global Satellite Measurement of Precipitation (GSMaP version 08) data which were released in December 2021, for the Indonesian Maritime Continent (IMC), using rain gauge (RG) observations from December 2021 to June 2022.Assessmentswere carried out with 586 rain gauge (RG) stations using a point-to-pixel approach through continuous statistical metrics and contingency table metrics. It was found that the coefficient correlation (CC) of GSMaP version 08 products against RG observation vary from low (CC=0.14-0.29), moderate (CC=0.33-0.45), and good correlation (CC=0.72-0.75), for the hourly, daily, and monthly scales with a tendency to overestimate, indicated by a positive RB. Even though the correlation of hourly datais still low, GSMaP can still capture diurnal patterns in the IMC, as indicated by the compatibility of the estimated peak times for the precipitation amount andfrequency. GSMaP data also managed to observe heavy rainfall, as indicated by the good probability of detection (POD) values ​​for daily data ranging from 0.71 to 0.81. Such a good POD value of daily data is followed by a relatively low false alarm ratio (FAR) (FAR<0.5). GSMaP daily data accuracy also dependson topographic conditions at IMC, especially for GSMaP real-time data. Of all GSMaP version 08 products evaluated, post-real time non-gauge calibrated (GSMaP_MVK) outperformed, followed by post-real time gauge calibrated (GSMaP_Gauge), near-real-time gauge calibrated (GSMaP_NRT_G), near-real time non-gauge callibrated (GSMaP_NRT), real time gauge callibrated (GSMaP_Now_G), and real time non-gauge callibrated (GSMaP_Now). Thus, GSMaP near real-time data has the potential for observing rainfall in IMC with faster latency.
lndolocarbazoles as Anti-Cancer Agents
Authors: Prudhomme Michelle 
Published: October 2022

Abstract:
Protein kinase C (PKC) is a family of phospholipid-dependent serine/threonine protein kinases that plays a key role in signal transduction. Consequently, PKC controls a large variety of cellular processes such as proliferation and differentiation as well as smooth muscle contraction and secretions. The disruption of these processes would have severe implications for many physiological functions. The twelve known PKC isoenzymes show great variations in their substrate specificity and their distribution among different tissues, indicating their specialised role in certain tissue functions. Altered expression of PKC isoenzymes has been reported in a wide range of diseases.
DNA topoisomerase I is a nuclear enzyme, involved in replication, transcription and recombination, that modifies and regulates the topological state of DNA.
Many microbial metabolites and synthetic compounds possessing an indolocarbazole unit are biologically active products with antitumor properties. Antibiotic indolocarbazoles staurosporine, K-252a, UCN-01 and 02 are known protein kinase C inhibitors while structurally related rebeccamycin and ED-110 are topoisomerase I inhibitors without inhibitory effect against PKC. This review will update efforts made toward the discovery of antitumor indolocarbazoles and their possible mode of action via either PKC or topoisomerase I inhibition. Structure-activity relationship studies in a series of maleamide and maleimide indolocarbazoles bearing or not a sugar moiety linked either to both indole nitrogens such as staurosporine, or to one indole nitrogen such as rebeccamycin, will be reported.
Strength of Lightweight Structural Concrete Acting under Imposed Load
Authors: Okolnikova Galina Erikovna , Al-shaibani Fouad Adnan Noman Abdullah , Saad Lina Abass , Naji Abdullah Abdulrahman saeed , Durutlu Kemal , Chiadighikaobi Paschal Chimeremeze 
Published: October 2022

Background:
Expanded polystyrene granules (EPG) can be used as an aggregate for producing lightweight concrete (LWC). EPG was used to make LWC with a density of 1326kg/m3 and 1337kg/m3, while the EPG concrete without fiber had a density of 1320kg/m3. Due to the low strength and brittleness of EPG LWC, the need to improve the properties of this concrete type is necessary.

Objective:
The aim of this paper was to research and investigate possible ways of enhancing the mechanical properties of EPG LWC. Hence, the investigation of this research work focuses on the use of chopped basalt fiber (BF) and steel fiber (SF) separately as dispersed reinforcement in EPG concrete to improve the compressive strength of EPG LWC.

Methods:
A general review from previous researchers on similar research was conducted, and then the experimental method was used to investigate the effect of BF and SF on the compressive strength of EPG LWC. Nine EPG concrete series were produced and tested. Compression testing was used to measure the compressive strength of the concrete sample. The density was determined by mass volume.

Results:
The results show the effect of BF and SF in the EPG concrete. The EPG reinforced with BF obtained its maximum compressive strength when 1.5% BF was incorporated in the EPG concrete and while EPG concrete reinforced with SF obtained its maximum compressive strength when 1% SF was included in the EPG concrete.

Conclusion:
Based on the results, the amount of fiber added to the EPG concrete affects not just the compressive strength but also the concrete density.
Teachers’ beliefs about the trends of current physical education
Authors: Nampai Udon , Setiawan Caly , Yeats Jeremy T. 
Published: October 2022

The purpose of this study was to investigate the beliefs among professionals in the field of physical education in elementary level, more specifically in the context of Thailand. The participants were five exemplary elementary PE teachers. All participants signed informed consent prior to data collection. We used semi-structured interviews in order to gather information of participants’ beliefs. Each interview lasted approximately 45 minutes. All interviews were audio recorded and later transcribed for analysis. Data collection occurred in two ways: (a) in-depth semi-structured interviews (b) semi-structured follow-up interviews. Data were analyzed using a thematic coding procedure in order to find the significant statements that related to research questions. Results showed three themes constructed from data analysis including trends: (1) to teach foundation of basic skills that moved beyond sport oriented PE, (2) to consider physical education for Health and the integrated physical education, and (3) to perceive limited time to deliver contemporary physical education. We conclude that the beliefs about the trends in physical education has been aligned with the global trends in physical education. These cover topic areas of skill development and health issues with strong emphasis on physical education that serves the best interests of the children. Relevant stakeholders should then ensure that physical education will be delivered according to the interest of today’s children. Future research should seriously focus on this specific area of study, encompassing policy, program, and practice of physical education.
An Assessment Of High School Leavers’ Development of Mathematical Thinking
Authors: Singh Parmjit , Teoh Sian Hoon , Md Nasir Nurul Akmal , Cheong Tau Han , Md Rasid Norsyazwani 
Published: October 2022

This descriptive design study evaluated the mathematical thinking attainment level of 649 High School leavers, ages 18 to 19 years, in the context of their preparation for facing the challenges of the tertiary level math curriculum. The findings depict students' low level of mathematical thinking attainment regarding their paucity in critical thinking and a lack of heuristics repertoire as a guide to employing their contextual knowledge in solving fundamental non-routine problems. These findings are a matter of concern as there seems to be a mutual exclusivity between the content learned in school and the ability of students to think mathematically.
Keywords: Mathematical Thinking; Non-Routine; Problem-Solving; Heuristics
eISSN: 2398-4287 © 2022. The Authors. Published for AMER ABRA cE-Bs by e-International Publishing House, Ltd., UK. This is an open-access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). Peer–review under the responsibility of AMER (Association of Malaysian Environment-Behaviour Researchers), ABRA (Association of Behavioural Researchers on Asians) and cE-Bs (Centre for Environment-Behaviour Studies), Faculty of Architecture, Planning & Surveying, Universiti Teknologi MARA, Malaysia.
DOI: https://doi.org/10.21834/ebpj.v7iSI8.3907
Rapid Prototyping of Species Classifiers using Deep Learning: A Guide for Non-Experts
Authors: Chege Herman Njoroge 
Published: October 2022

Deep learning algorithms are revolutionizing how hypothesis generation,
pattern recognition, and prediction occur in the sciences. In the life
sciences, particularly biology, and its subfields, the use of deep
learning is slowly but steadily increasing. However, prototyping or
development of tools for practical applications remains in the domain of
experienced coders. Furthermore, many tools can be quite costly and
difficult to put together without expertise in Artificial intelligence
(AI) computing. We built a biological species classifier that leverages
existing open-source tools and libraries. We designed the corresponding
tutorial for users with basic skills in python and a small, but
well-curated image dataset. We included annotated code in form of a
Jupyter Notebook that can be adapted to any image dataset, ranging from
satellite images, animals to bacteria, or even data such as song or
echolocation recordings transformed into images. The prototype developer
is publicly available and can be adapted for citizen science as well as
other applications not envisioned in this paper.
We illustrate our approach with a case study of 219 images of 3 three
seastar species. We show that with minimal parameter tuning of the AI
pipeline we can create a classifier with 87% accuracy. We include
additional approaches to understand the misclassified images and to
curate the dataset to increase accuracy. The power of AI approaches is
becoming increasingly accessible. We can now readily build and prototype
species classifiers that can have a great impact on research that
requires species identification and other types of image analysis. Such
tools have implications for citizen science, biodiversity monitoring,
and a wide range of ecological applications.
Identifying Hyperreflective Foci in Diabetic Retinopathy via VEGF-induced Local Self-Renewal of CX3CR1+ Vitreous Resident Macrophages
Authors: Yamaguchi Muneo , Nakao Shintaro , Wada Iori , Matoba Tetsuya , Arima Mitsuru , Kaizu Yoshihiro , Shirane Mariko , Ishikawa Keijiro , Nakama Takahito , Murakami Yusuke , Mizuochi Masaharu , Shiraishi Wataru , Yamasaki Ryo , Hisatomi Toshio , Ishibashi Tatsuro , Shibuya Masabumi , Stitt Alan W. , Sonoda Koh-Hei 
Published: October 2022

<p>Intraretinal hyperreflective foci (HRF) are significant biomarkers for diabetic macular edema. However, HRF at the vitreoretinal interface (VRI) have not been examined in diabetic retinopathy (DR). A prospective observational clinical study with 162 consecutive eyes using OCT imaging showed significantly increased HRF at the VRI during DR progression (<em>P</em><0.01), which was reversed by anti-VEGF therapy. F4/80+ macrophages increased significantly at the VRI in Kimba (<em>vegfa</em>+/+) or Akimba (Akita × Kimba) mice (both <em>P</em><0.01), but not in diabetic Akita (<em>Ins2</em>+/-) mice, indicating macrophage activation was modulated by elevated VEGF rather than the diabetic milieu. Macrophage depletion significantly reduced HRF at the VRI (<em>P</em><0.01). Furthermore, BrdU administration in <em>Ccr2</em>rfp/+<em>Cx3cr1</em>gfp/+ <em>vegfa</em>+/- mice identified a significant contribution of M2-like tissue-resident macrophages (TRMs) at the VRI. Ki-67- and CD11b-positive cells were observed in preretinal tissues of DR patients while exposure of vitreal macrophages to vitreous derived from PDR patients induced a significant proliferation response <em>in vitro</em> (<em>P</em><0.01). Taken together, the evidence suggests that VEGF drives a local proliferation of vitreous resident macrophages (VRMs) at the VRI during DR. This phenomenon helps to explain the derivation and disease-relevance of the HRF lesions observed through OCT imaging in patients.<br>
</p>
Study on andorite-series minerals from Meleg Hill, Velence Mts., Hungary
Authors: Papp Richárd Zoltán , Topa Boglárka Anna , Zajzon Norbert 
Published: October 2022

During the last decades, different sulphosalts were observed in several samples that were investigated from the Meleg hill, Velence Mts. The investigated sample of this study was collected from the less studied north-eastern, stibnite-rich part of the hydrothermal breccia at the Meleg Hill. Based on the results of electron microprobe analysis, we found that the sample contained two sulphosalt minerals of the andorite series that have not been described from Hungary before. The andorite series is a subgroup of the lillianite homologous series. The individual minerals, andorite VI and roshchinite, within the andorite series were identified on the basis of their chemical composition and the andorite substitution percentage (L%). Andorite VI has Ag1.06Cu0.04Pb0.80Sb2.49Bi0.22As0.3S6 average chemical formula (normalized to 6 sulphur atoms) and L%=102.65–109.84, whereas roshchinite has Ag17.23Cu0.53Pb10.4Hg0.04Zn0.04Fe0.02Sb39.73Bi5.52As5.98S96 average chemical formula (normalized to 96 sulphur atoms) and L% = 119.52–123.48. Our results suggest that the formerly used comparative ternary diagrams of the system (Ag2S + Cu2S)–(Sb2S3 + Bi2S3 + As2S3)–(PbS + HgS + FeS + ZnS + CdS) is not adequate to differentiate the andorite-series minerals from each other, due to the highly variable element substitution of Me+, Me2+ and Me3+ cations. The andorite substitution percentage (L%) and the andorite homologue order value (N) are always necessary to calculate to distinguish the mineral species.
ANALISIS TEGANGAN PADA POROS ENGKOL SEPEDA MOTOR HONDA GL PRO NEOTECH MENGGUNAKAN SOLIDWORKS 2021
Authors: Iski Muhammad Iqbal , Sari Delima Yanti , Nurdin Hendri , Irzal Irzal 
Published: October 2022

Sepeda motor terdapat salah satu komponen penting yaitu poros engkol (crankshaft). Poros engkol adalah komponen dengan geometri yang kompleks pada mesin pembakaran, berfungsi mengubah gerak translasi (gerak bolak-balik) piston menjadi gerak berputar terhadap poros. Poros engkol dioperasikan pada putaran tinggi sehingga poros engkol mengalami beban siklus yang cukup besar. Penelitian ini bertujuan untuk menginvestigasi beban yang terjadi pada poros engkol Honda GL Pro Neotech berbahan material AISI 1045 Steel, cold drawn dengan melakukan analisis static structural dengan tipe meshing tetrahedral 3D solid elements pada poros engkol menggunakan Solidworks 2021. Metode penelitian yang digunakan adalah menggunakan simulasi komputer dengan software berbasis Metode Elemen Hingga. Dilakukan untuk mendapatkan besarnya nilai tegangan yang terjadi pada lokasi kritis, perpindahan yang terjadi pada poros engkol dan faktor keamanan. Model poros engkol 3D dibuat melalui software Solidworks 2021. Beban kemudian diterapkan pada crankpin dan kondisi batas diterapkan pada crank journal. Hasil yang diperoleh dari analisis tersebut untuk mengetahui distribusi tegangan Von Mises, perpindahan dan faktor keamanan pada poros engkol akibat pembebanan secara statik. Gaya reaksi yang disebabkan gaya aksi yang diberikan terhadap crankpin sebesar 11.659,28 N. Kesimpulan dari penelitian ini adalah diketahuinya nilai tegangan Von Mises, perpindahan, dan faktor keamanan melalui hasil simulasi Solidworks. Didapatkan tegangan Von Mises maksimum sebesar 4,777e+01 N/mm2 dan tegangan Von Mises minimum sebesar 1,704e-08 N/mm2, perpindahan maksimum diperoleh sebesar 2,543e-03 mm dan FOS (factor of safety) minimum diperoleh sebesar 1,109+01.
ANALISA PERBANDINGAN HASIL PENGELASAN LAS SMAW DENGAN LAS MIG PADA POSISI 3G DENGAN MATERIAL JIS G3101 SS400
Authors: Shiddiq Muhammad , Irzal Irzal , Purwantono Purwantono , Fernanda Yolli 
Published: October 2022

Kemajuan dunia teknologi dibidang kontruksi semakin berkembang tidak terpisah dari pengelasan, pada penelitian perbandingan jenis pengelasan ini didapatkan indentifikasi suatu masalah, dimana belum ditemukan perbandingan hasil dari pengelasan SMAW dan pengelasan MIG pada posisi 3G. pada penelitian perbandingan jenis pengelasan ini mempunyai tujuan menemukan hasil dari perbandingan pengelasan las SMAW dengan las MIG pada posisi 3G. Penelitian ini menggunakan material JIS G3101 SS400. Penelitian ini menggunakan jenis metode eksperimen yang dimulai dengan pembuatan kampuh V pada spesimen, melakukan pengelasan spesimen, dengan membuat bentuk spesimen yang sesuai dengan standar ASTM E190. Untuk pengambilan data sebanyak 10 spesimen dimana, 5 pengelasan las SMAW dan 5 spesimen pengelasan las MIG. Setelah melakukan uji bending tiap-tiap spesimen dianalisa agar dapat dirumuskan kesimpulan dimana, angkanya yang tertingi maka spesimen tersebut yang mempunyai nilai kekuatan lebih baik, dengan hasil penelitian yang didapatkan oleh spesimen, dengan proses pembuatan ukuran spesimen dan pengelasan serta menguji hasil pada spesimen dengan bantuan mesin bending test, dengan ditemukan nilai rata-rata pengelasan SMAW awal terjadinya retakan 2 mm pada sudut 160,8 dengan beban sebesar 8,3 KN. Pada spesimen las MIG nilai rata-rata awal terjadi retakan 2,4 mm pada sudut 176,2 dengan beban sebesar 1,82 KN. Hasil pebandingan kekuatan pengelasan pada material JIS G3101 SS400 dengan jenis pengelasan SMAW lebih tinggi dari hasil pengelasan las MIG.