bluuebunny/crossref_metadata_2025_split huggingface dataset:
More work is needed on cost‐utility analyses of robotic‐assisted surgery
Authors: Bai Fei , Li Meixuan , Han Jiani , Qin Yu , Yao Liang , Yan Wenlong , Liu Yujun , He Gege , Zhou Yinjuan , Ma Xiaoya , Aboudou Taslim , Guan Ling , Lu Mengying , Wei Zhipeng , Li Xiuxia , Yang Kehu 
Published: June 2022

AbstractObjectiveTo comprehensively analyze the cost‐utility of robotic surgery in clinical practice and to investigate the reporting and methodological quality of the related evidence.MethodsData on cost‐utility analyses (CUAs) of robotic surgery were collected in seven electronic databases from the inception to July 2021. The quality of the included studies was assessed using the CHEERs and QHES checklists. A systematic review was performed with the incremental cost‐effectiveness ratio as the outcome of interest.ResultsThirty‐one CUAs of robotic surgery were eligible. Overall, the identified CUAs were fair to high quality, and 63% of the CUAs ranked the cost‐utility of robotic surgery as “favored,” 32% categorized as “reject,” and the remaining 5% ranked as “unclear.” Although a high heterogeneity was present in terms of the study design among the included CUAs, most studies (81.25%) consistently found that robotic surgery was more cost‐utility than open surgery for prostatectomy (ICER: $6905.31/QALY to $26240.75/QALY; time horizon: 10 years or lifetime), colectomy (dominated by robotic surgery; time horizon: 1 year), knee arthroplasty (ICER: $1134.22/QALY to $1232.27/QALY; time horizon: lifetime), gastrectomy (dominated by robotic surgery; time horizon: 1 year), spine surgery (ICER: $17707.27/QALY; time horizon: 1 year), and cystectomy (ICER: $3154.46/QALY; time horizon: 3 months). However, inconsistent evidence was found for the cost‐utility of robotic surgeryversuslaparoscopic surgery and (chemo)radiotherapy.ConclusionsFair or high‐quality evidence indicated that robotic surgery is more cost‐utility than open surgery, while it remains inconclusive whether robotic surgery is more cost‐utility than laparoscopic surgery and (chemo)radiotherapy. Thus, an additional evaluation is required.
Have you found what you are looking for? How values orientations affect pro‐social change after transformative service experiences
Authors: Hamby Anne , Farrell Justine Rapp 
Published: June 2022

AbstractPast research on transformative service experiences suggests that participating individuals may experience positive, as well as (unintended) negative well‐being consequences. Most of this work has examined aspects of the service provider and the service experience as a causal factor, underemphasizing aspects of the participants in such experiences as a determinant. Implementing a longitudinal design in the context of a cross‐country bike trip to benefit multiple sclerosis, the authors investigate how changes in participants' civic attitudes and skills, as well as perceived personal change and connection to the experience, may depend upon the participants' underlying values orientation. Emerging findings indicate that values associated with achievement and growth may lead to undesirable changes in civic attitudes, while values associated with external validation promote positive personal change and enhanced connection to the organization and cause. Implications for transformative service organizations and research limitations are discussed.
The new world of philanthropy: How changing financial behavior, public policies, and COVID‐19 affect nonprofit fundraising and marketing
Authors: Van Steenburg Eric , Anaza Nwamaka A. , Ashhar Ahmed , Barrios Andres , Deutsch Ashley R. , Gardner Meryl P. , Priya Preeti , Roy Abhijit , Sivaraman Anu , Taylor Kimberly A. 
Published: June 2022

AbstractEvolving financial behavior, an unpredictable public policy atmosphere, and an unparalleled global pandemic have collaborated to disrupt nonprofit fundraising. The COVID‐19 pandemic alone exacerbated consumer demands for nonprofit services while curtailing nonprofit organizations' ability to fundraise. Without fundraising, nonprofit organizations cannot achieve their mission or support their causes, leading to a precarious situation for societal well‐being. Meanwhile, consumers are changing their financial behaviors, with younger generations often going cashless. At the same time, governments continue to change policies that affect nonprofit organizations. In keeping with the transformative consumer research movement, the present study provides a conceptual framework for the state of nonprofit fundraising amid the challenges associated with changes in financial behavior and public policy, coupled with the effects of the global pandemic. Marketing strategies for fundraising success are presented to aid nonprofits going forward and serve societal interests.
Childhood experience of parental affection and financial well‐being in later life: Evidence from the Health and Retirement Study
Authors: Pak Tae‐Young , Fan Lu 
Published: June 2022

AbstractChildhood experience of parental affection has been shown to be influential in numerous domains of a child's life. Using a nationally representative sample of older Americans, this study examined the association between childhood experience of parental affection and financial well‐being four to five decades later. Consistent with the literature, childhood experience of parental affection was found to be positively related to both objective and subjective financial well‐being, as evidenced by greater total assets and lower total debt, debt‐to‐assets ratio, propensity to experience difficulty paying bills, and financial satisfaction. The results were robust to controlling for early life characteristics of parents and family, as well as addressing potential recall bias in retrospective reports. Our findings suggest that parental affection in childhood exerts a long‐lasting influence on financial well‐being, which persists into later life. Early intervention for those who lack parental affection may complement financial education programs and yield significant lifetime benefits.
The significant value of sustainable cosmetics fragrance in the spotlight after COVID‐19
Authors: Lee Jinkyung , Kwon Ki Han 
Published: June 2022

AbstractBackgroundThe coronavirus disease 2019 (COVID‐19) pandemic has brought major changes to the world's population. This has led to increased wearing of masks to prevent infectious diseases, which can contribute to exacerbation of stress and the emergence of mental illness due to a physical health crisis.ObjectivesTherefore, this study comprehensively investigated the reasons why cosmetics customers pay attention to sustainable fragrances after COVID‐19.MethodsThis review article is a literature review, and a narrative review approach was used in this study. A total of 598 references were selected from 2004 to 2022 using representative journal search sites such as PubMed, Google Scholar, Scopus, and RISS. Among them, a total of 39 articles were successfully completed in this study using the PRISMA flowchart in the final stage.ResultsIn this study, by identifying the changes and needs of K‐beauty and global cosmetics industry consumers who aspire for sustainable safety amid the COVID‐19 pandemic, the increase in bad breath caused by the increase in mask wearing was recognized, and the need for fragrance due to mental health was recognized. Demand is expected to increase.ConclusionThis study tried to change the perception of cosmetic fragrances into safe edible fragrances. Therefore, it is expected to be used as an important marketing material for the global cosmetics market.
Ultrasonographic analyses of Crow's feet and novel guideline for botulinum toxin injection
Authors: Piao Jiong‐Zhen , Oh Wook , Choi You‐Jin , Lee Ji‐Hyun , Bae Hyungkyu , Hu Kyung‐Seok , Kim Hyoung‐Moon , Kim Hee‐Jin 
Published: June 2022

AbstractBackgroundCrow's feet are bilateral orbital wrinkles formed by the orbital portion of the orbicularis oculi muscle, which is the target muscle for botulinum neurotoxin (BoNT) injection.ObjectivesThis study's aim was to demonstrate a novel BoNT injection guideline by assessing muscle width, thickness, and dynamic features using ultrasonography.MethodsTwenty healthy Korean volunteers (10 men, 10 women; mean age, 25.6) participated. The width, thickness, and dynamic movement of the orbicularis oculi muscle were measured using ultrasonography. Two volunteers were selected to receive BoNT injections. Injections were administered using a novel method with two curved reference lines passing a point 15 mm lateral to the lateral canthus (conventional injection) and a point 5 mm lateral to the lateral margin of the frontal process of zygomatic bone (additional injection).ResultAt the lateral canthus level, the distance between the lateral margin of the frontal process and the most lateral margin of the orbicularis oculi muscle was 12.5 ± 1.3 mm. The thickness of the orbicularis oculi muscle at the midpoint of the frontal process, the lateral marginal of the frontal process, and 5 mm lateral to the lateral marginal of the frontal process was 0.7 ± 0.3 mm, 1.1 ± 0.3 mm, and 1.2 ± 0.3 mm, respectively. The crow's feet of the two volunteers began to disappear from day 3 and completely disappeared on day 7 after the injection.ConclusionThe novel injection technique based on the ultrasonographic anatomy resulted in improvements in the appearance of crow's feet.
How Managers Respond to Paradoxical Control‐Trust Dynamics in Interorganizational Relationships over Time: A Constitutive Approach
Authors: Vedel Jane Bjørn , Geraldi Joana 
Published: June 2022

AbstractControl‐trust dynamics are fundamental to organizational life, but managers struggle to balance them because these dynamics draw on opposing mechanisms. Past research has mainly assumed that substitution and complementarity constitute key control‐trust dynamics, which has limited scholars' understanding of why these dynamics are difficult to balance and how managers deal with them over time. We explore managers' responses to paradoxical control‐trust dynamics. We conducted a longitudinal case study of how managers in a pharmaceutical company dealt with these dynamics in an interorganizational relationship with a university and a biotech firm. Our findings show (a) a new category of response to control‐trust dynamics beyond substitution and complementarity (the More‐Than), (b) three new enacted responses beyond balancing (paradoxical thinking, fulfilling promises, and transcending), and (c) a governance path that managers' responses evolve over time. Our findings suggest that managers' responses to paradoxical control‐trust dynamics ensure the performance and endurance of interorganizational relationships.
Being and becoming: A psychobiography of James Baldwin
Authors: Reynolds (Taewon Choi) Jason D. , Miller Simonleigh P. , Maleh Nicole T. 
Published: June 2022

AbstractIntroductionJames Baldwin (1924–1987) was a prolific African American author and activist whose writing centered primarily on race, sexuality, and religion. Baldwin’s lived experiences and breadth of knowledge provided him with a unique perspective of the Black experience in America, a theme he frequently revisited in his work and the impetus for his involvement in the Civil Rights MovementMethodThis article presents a psychobiographical application of Queering Black Racial Identity Development to conceptualize the life story of James Baldwin.ResultsThis study explores the life of James Baldwin, highlights his influence as a historical figure and agent of social change, and explores the “why” of his life and behavior. Specifically, his decision to return to the United States during the Civil Rights Movement and possible reasons he avoided politicizing his sexuality in the same way he did his racial identity.ConclusionAs an African American, nonheterosexual, male author and Civil Rights activist, Baldwin’s intersectional identities played a significant role in his decision to dedicate his life to writing and activism. Limitations of the study are discussed.
A trans agent of social change in incarceration: A psychobiographical study of Natasha Keating
Authors: du Plessis Carol , Halliwell Sherree D. , Mullens Amy B. , Sanders Tait , Gildersleeve Jessica , Phillips Tania , Brömdal Annette 
Published: June 2022

AbstractObjectivesThis psychobiography focuses on the advocacy work of Natasha Keating, a trans woman incarcerated in two male prisons in Australia between 2000 and 2007. Incarcerated trans women are a vulnerable group who experience high levels of victimization and discrimination. However, Natasha advocated for her rights while incarcerated and this advocacy contributed to substantial changes in the carceral system. This psychobiography uses psychological understandings of resilience as well as the Transgender Resilience Intervention Model (TRIM) to investigate the factors that enabled this advocacy.MethodData consisted of an archive of letters written by Natasha and interviews with individuals who knew her well. This psychobiography was guided by du Plessis' (2017) 12‐step approach and included the identification of psychological saliencies and the construction of a Multilayered Chronological Chart.ResultsNatasha's life is presented in four chapters, with each chapter including a discussion of resilience based on the TRIM.ConclusionsThe TRIM suggests that during incarceration, Natasha was able to access more group‐level resilience factors than at any other time in her life. This, combined with individual resilience factors, enabled her advocacy. This finding has implications for advocacy in general as it highlights the importance of both individual‐ and group‐level factors in enabling individuals to effectively advocate for change in their environments.
A comparative study of antagonistic activity spectra of lactic acid bacteria isolated from fermented foods
Authors: Garmasheva I.L. , Oleschenko L.T. 
Published: June 2022

Abstract
The present work aimed to assess the general antagonistic activity against opportunistic pathogens and to compare antagonistic action spectra of lactic acid bacteria (LAB) strains, isolated from Ukrainian traditional fermented foods. Overall, 161 profiles of the antagonistic activity spectrum were obtained from 1056 LAB strains. Among them, 114 profiles were genus-specific and 47 spectra of antagonistic activity were found in LAB strains of different genera. Furthermore, 19 LAB strains were active only against Gram-negative indicator strains and 149 LAB strains only against Gram-positive indicator strains. The size of growth inhibition zones of indicator strains by LAB strains of each genus did not correlate with the level of acidification. Zones of growth inhibition of indicator strains appeared after 6–8 h of incubation and in most cases decreased with further incubation, up to absence after 24 h. The difference in the antagonistic activity of 16-h-old and 24-h-old hours LAB cultures also was found. Among LAB tested, 241 strains are the most promising for further practical use, they have antagonistic action towards 10 indicator strains. The cross-streaking method can be used for rapid screening of bacteriocinogenic LAB strains and has advantages over the well-diffusion assay. To the best of our knowledge, this is the first report on a comparative characteristic of spectra of antagonistic activity against opportunistic pathogens of LAB strains belonging to different genera.
New insights into development and mortality of COVID‐19‐associated pulmonary aspergillosis in a homogenous cohort of 1161 intensive care patients
Authors: Hashim Zia , Nath Alok , Khan Ajmal , Neyaz Zafar , Marak Rungmei S. K. , Areekkara Prasant , Tiwari Atul , Srivastava Shivani , Agarwal Vikas , Saxena Swati , Tripathy Nidhi , Azim Afzal , Gupta Mansi , Mishra Durga Prasanna , Mishra Prabhakar , Singh Ratender Kumar , Gupta Devender , Gupta Anshul , Sanjeev Om Prakash , Ghatak Tanmoy , Ghoshal Ujjala , Dhiman Radha Krishan , Tripathy Naresh Kumar 
Published: June 2022

AbstractBackgroundCOVID‐19‐associated pulmonary aspergillosis (CAPA) has been widely reported but homogenous large cohort studies are needed to gain real‐world insights about the disease.MethodsWe collected clinical and laboratory data of 1161 patients hospitalised at our Institute from March 2020 to August 2021, defined their CAPA pathology, and analysed the data of CAPA/non‐CAPA and deceased/survived CAPA patients using univariable and multivariable models.ResultsThe overall prevalence and mortality of CAPA in our homogenous cohort of 1161 patients were 6.4% and 47.3%, respectively. The mortality of CAPA was higher than that of non‐CAPA patients (hazard ratio: 1.8 [95% confidence interval: 1.1–2.8]). Diabetes (odds ratio [OR] 1.92 [1.15–3.21]); persistent fever (2.54 [1.17–5.53]); hemoptysis (7.91 [4.45–14.06]); and lung lesions of cavitation (8.78 [2.27–34.03]), consolidation (9.06 [2.03–40.39]), and nodules (8.26 [2.39–28.58]) were associated with development of CAPA by multivariable analysis. Acute respiratory distress syndrome (ARDS) (2.68 [1.09–6.55]), a high computed tomography score index (OR 1.18 [1.08–1.29]; p < .001), and pulse glucocorticoid treatment (HR 4.0 [1.3–9.2]) were associated with mortality of the disease. Whereas neutrophilic leukocytosis (development: 1.09 [1.03–1.15] and mortality: 1.17 [1.08–1.28]) and lymphopenia (development: 0.68 [0.51–0.91] and mortality: 0.40 [0.20–0.83]) were associated with the development as well as mortality of CAPA.ConclusionWe observed a low but likely underestimated prevalence of CAPA in our study. CAPA is a disease with high mortality and diabetes is a significant factor for its development while ARDS and pulse glucocorticoid treatment are significant factors for its mortality. Cellular immune dysregulation may have a central role in CAPA from its development to mortality.
Space, time and parsimony
Authors: Nolan Daniel 
Published: June 2022

AbstractThis paper argues that all of the standard theories about the divisions of space and time can benefit from, and may need to rely on, parsimony considerations. More specifically, whether spacetime is discrete, gunky or pointy, there are wildly unparsimonious rivals to standard accounts that need to be resisted by proponents of those accounts, and only parsimony considerations offer a natural way of doing that resisting. Furthermore, quantitative parsimony considerations appear to be needed in many of these cases.
Guanosine tetraphosphate (ppGpp) accumulation inhibits chloroplast gene expression and promotes super grana formation in the mossPhyscomitrium(Physcomitrella)patens
Authors: Harchouni Seddik , England Samantha , Vieu Julien , Romand Shanna , Aouane Aicha , Citerne Sylvie , Legeret Bertrand , Alric Jean , Li‐Beisson Yonghua , Menand Benoît , Field Benjamin 
Published: June 2022

SummaryThe nucleotides guanosine tetraphosphate and pentaphosphate (or (p)ppGpp) are implicated in the regulation of chloroplast function in plants. (p)ppGpp signalling is best understood in the model vascular plantArabidopsis thalianain which it acts to regulate plastid gene expression to influence photosynthesis, plant development and immunity. However, little information is known about the conservation or diversity of (p)ppGpp signalling in other land plants.We studied the function of ppGpp in the mossPhyscomitrium(previouslyPhyscomitrella)patensusing an inducible system for triggering ppGpp accumulation. We used this approach to investigate the effects of ppGpp on chloroplast function, photosynthesis and growth.We demonstrate that ppGpp accumulation causes a dramatic drop in photosynthetic capacity by inhibiting chloroplast gene expression. This was accompanied by the unexpected reorganisation of the thylakoid system into super grana. Surprisingly, these changes did not affect gametophore growth, suggesting that bryophytes and vascular plants may have different tolerances to defects in photosynthesis.Our findings point to the existence of both highly conserved and more specific targets of (p)ppGpp signalling in the land plants that may reflect different growth strategies.
Experimentally heat‐induced transposition increases drought tolerance in Arabidopsis thaliana
Authors: Thieme Michael , Brêchet Arthur , Bourgeois Yann , Keller Bettina , Bucher Etienne , Roulin Anne C. 
Published: June 2022

Summary

Eukaryotic genomes contain a vast diversity of transposable elements (TEs). Formerly often described as selfish and parasitic DNA sequences, TEs are now recognised as a source of genetic diversity and powerful drivers of evolution. However, because their mobility is tightly controlled by the host, studies experimentally assessing how fast TEs may mediate the emergence of adaptive traits are scarce.

We exposed Arabidopsis thaliana high‐copy TE lines (hcLines) with up to c. eight‐fold increased copy numbers of the heat‐responsive ONSEN TE to drought as a straightforward and ecologically highly relevant selection pressure.

We provide evidence for increased drought tolerance in five out of the 23 tested hcLines and further pinpoint one of the causative mutations to an exonic insertion of ONSEN in the ribose‐5‐phosphate‐isomerase 2 gene. The resulting loss‐of‐function mutation caused a decreased rate of photosynthesis, plant size and water consumption.

Overall, we show that the heat‐induced transposition of a low‐copy TE increases phenotypic diversity and leads to the emergence of drought‐tolerant individuals in A. thaliana. This is one of the rare empirical examples substantiating the adaptive potential of mobilised stress‐responsive TEs in eukaryotes. Our work demonstrates the potential of TE‐mediated loss‐of‐function mutations in stress adaptation.
MicroRNA‐21‐5p functions via RECK/MMP9 as a proalgesic regulator of the blood nerve barrier in nerve injury
Authors: Reinhold Ann Kristin , Krug Susanne M. , Salvador Ellaine , Sauer Reine S. , Karl‐Schöller Franziska , Malcangio Marzia , Sommer Claudia , Rittner Heike L. 
Published: June 2022

AbstractBoth nerve injury and complex regional pain syndrome (CRPS) can result in chronic pain. In traumatic neuropathy, the blood nerve barrier (BNB) shielding the nerve is impaired—partly due to dysregulated microRNAs (miRNAs). Upregulation of microRNA‐21‐5p (miR‐21) has previously been documented in neuropathic pain, predominantly due to its proinflammatory features. However, little is known about other functions. Here, we characterized miR‐21 in neuropathic pain and its impact on the BNB in a human‐murine back translational approach. MiR‐21 expression was elevated in plasma of patients with CRPS as well as in nerves of mice after transient and persistent nerve injury. Mice presented with BNB leakage, as well as loss of claudin‐1 in both injured and spared nerves. Moreover, the putative miR‐21 target RECK was decreased and downstream Mmp9 upregulated, as was Tgfb. In vitro experiments in human epithelial cells confirmed a downregulation of CLDN1 by miR‐21 mimics via inhibition of the RECK/MMP9 pathway but not TGFB. Perineurial miR‐21 mimic application in mice elicited mechanical hypersensitivity, while local inhibition of miR‐21 after nerve injury reversed it. In summary, the data support a novel role for miR‐21, independent of prior inflammation, in elicitation of pain and impairment of the BNB via RECK/MMP9.