bluuebunny/crossref_metadata_2025_split huggingface dataset:
Safety and Adequacy of Kidney Biopsy Procedure in Patients with Obesity
Authors: Qian Long , Menez Steven , Hu David , Weinstein Jason , Melchinger Hannah , Thiessen-Philbrook Heather , Luciano Randy L. , Turner Jeffrey M. , Perazella Mark A. , Corona Villalobos Celia Pamela , Shaw Melissa M. , Wilson F. Perry , Parikh Chirag R. , Moledina Dennis G. 
Published: November 2022

Key Points

Patients with obesity did not have any larger hematocrit drop after kidney biopsy compared with those without obesity.Patients with obesity had fewer glomeruli sampled from kidney biopsy compared with those without obesity.For patients with obesity, kidney biopsy is a safe procedure but may have lower diagnostic adequacy.
PPARδ Agonism Ameliorates Renal Fibrosis in an Alport Syndrome Mouse Model
Authors: Omachi Kohei , O'Carroll Colin , Miner Jeffrey H. 
Published: November 2022

Key Points

A peroxisome proliferator-activated receptor δ agonist, REN001, ameliorates kidney dysfunction in a mouse model of Alport syndrome.REN001 suppresses glomerular injury and renal fibrosis.REN001 decreases the levels of inflammation- and fibrosis-related proteins.

Background
Alport syndrome is a genetic kidney disease caused by mutation in any of the COL4A3, COL4A4, or COL4A5 genes encoding the type IV collagen α3, α4, and α5 chains. Defects of type IV collagen α3α4α5 cause glomerular basement membrane abnormalities and lead to defects in glomerular filtration and ESKD. Treatment with angiotensin-converting enzyme inhibitors (ACEis) dramatically slows disease progression but does not stop progression to renal failure. Therefore, novel therapeutic options with different modes of action from ACEis are needed. Peroxisome proliferator-activated receptor (PPAR) δ agonists have shown renoprotective effects in several acute kidney injury mouse models. In this study, we investigated the effects of a potent and selective PPARδ agonist, REN001 (formerly HPP593), in a mouse model of Alport syndrome.

Methods
We administered REN001 from the early stages to the late stages of disease by once daily intraperitoneal injections.

Results
REN001 treatment halved proteinuria at the late stages of disease in Col4a3

−/−
mice. BUN levels were also decreased, and histological and molecular analyses showed that REN001 ameliorated renal inflammation and fibrosis.

Conclusions
These results indicate that REN001 slows kidney disease progression in Alport mice. REN001 has a different mechanism of action from ACEis, so we, therefore, hypothesize that combining the two treatments may show additive effects to attenuate renal injury and slow progression to renal failure.
LAJU PERTUMBUHAN LARVA IKAN SEURUKAN (Osteochilus vittatus) DENGAN PEMBERIAN KUNING TELUR UNGGAS
Authors: Mahendra Mahendra , Supriadi Supriadi 
Published: November 2022

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian kuning telur unggas dan jenis yang terbaiknya terhadap laju pertumbuhan larva seurukan. Penelitian ini menggunakan metode eksperimen dengan Rancangan Acak Lengkap (RAL) yang terdiri atas 4 perlakuan dan 3 ulangan. Perlakuan yang diberikan adalah P0: telur ayam ras; P1: telur puyuh; P2: telur itik; P3: telur ayam kampung/lokal. Parameter yang diamati meliputi laju pertumbuhan spesifik (SGR), laju pertumbuhan relatif (RGR), serta kualitas air sebagai data penunjang. Hasil penelitian menunjukan bahwa pemberian telur unggas yang terbaik adalah pada perlakuan P2 dengan nilai SGR 15 %/hari dan RGR 26 %/hari.
Webinar Analisis Efisiensi Perusahaan Dengan DEA
Authors: Mulyadi JMV 
Published: November 2022

Abstrak
Tujuan pelatihan ini adalah menjelaskan metode Data Envelopment Analyisis (DEA) sebagai alat analisis efisiensi perusahaan. Penjelasan mencakup pengertian, manfaat, mekanisme, formulasi model DEA dan penggunaan Software Banxia Frotier Analist dan MaxDEA. Pelatihan dilakukan dengan Webinar Nasional yang dilaksanakan atas kerjasama Sekolah Pascasarjana Universitas Pancasila dengan Muhammadiyah Ranting Mampang Kota Depok. Hasilnya menunjukkan bahwa metode DEA sangat bermanfaat dan jika dimungkinkan waktunya ditambah dan diperdalam dengan contoh-contoh. Implikasi akademisnya peserta membuat tutorial youtube bagaimana mengoperasikan software Banxia Frontier Analist dan dapat membantu mahasiswa dalam menyusun tesis.
Kata Kunci: data envelopment analysis, efisiensi, banxia frontier analist, maxdea.

Abstract
The purpose of this training is to explain the Data Envelopment Analysis (DEA) method as a company efficiency analysis tool. The explanation includes the meaning, benefits, mechanisms, formulation of the DEA model and the use of the Banxia Frotier Analist and MaxDEA Software. The training was carried out with a National Webinar which was held in collaboration with the Postgraduate School of Pancasila University and the Muhammadiyah Branch of Mampang Depok City. The results show that the DEA method is very useful and if possible the time is added and deepened with examples. The academic implication is that the participants make a youtube tutorial on how to operate the Banxia Frontier Analist software and can help students in preparing a thesis.
Keywords: data envelopment analysis, efficiency, banxia frontier analist, maxdea.
Aplikasi EFA (Excel For Accounting) untuk Laporan Keuangan Pesantren
Authors: Ahmar Nurmala 
Published: November 2022

Abstrak
Pedoman Akuntansi Pesantren diterbitkan oleh Ikatan Akuntan Indonesia pada Mei 2018. Berdasarkan data Kementerian Keagamaan Republik Indonesia (Kemenag RI) terdapat total sebanyak belasan juta santri dan mendekati angka tiga puluh ribu pondok pesantren di berbagai wilayah se-Indonesia. Salah satu program untuk mendorong adalah peningkatan tata kelola yang baik di lingkungan pesantren melalui tersedianya laporan keuangan yang memenuhi standar akuntansi yang diterima secara luas dan diterima berbagai pihak. Artikel ini menyumbangkan karya pengabdian dalam bentuk pelatihan akuntansi pesantren dengan aplikasi EFA untuk memidakan penyusunan laporan keuangan pesantren.
Kata Kunci: aplikasi program, excel for accounting, akuntansi pesantren, laporan aktivitas.

Abstract
Pedoman Akuntansi Pesantren Published by the Ikatan Akuntan Indonesia in May 2018. Based on data from kementerian Agama republik Indonesia, there are a total of tens of millions of students and a count of thirty thousand Islamic boarding schools in various regions throughout Indonesia. One of the programs to encourage is the improvement of good governance in the pesantren environment through financial reportsthat meet accounting standards that are widely accepted and accepted by various parties. This article contributed dedication work in the form of Islamic boarding school accounting training with the EFA application for preparing Islamic boarding school financial reports.
Keywords: software, excel for accounting, pesantren, activity report accounting.
Sosialisasi Covid-19 dan Protokol Kesehatan sebagai Edukasi Masyarakat pada Sosial Media Instagram dan Tiktok
Authors: Handayani Dewi Aprilia , Rosit Muhammad 
Published: November 2022

ABSTRAK
Pandemi Covid-19 memiliki banyak dampak untuk segala aspek, seperti ekonomi, sosial budaya, pendidikan dan terkhusus pada kesehatan. Indonesia termasuk kedalam negara dengan jumlah kasus yang meningkat dengan pesat. Penanganan terhadap krisis tersebut harus dilakukan secara ketat oleh pemerintah serta dukungan dari kesadaran masyarakat. Kedisiplinan dalam menerapkan protokol kesehatan wajib dilakukan oleh semua pihak demi menekan serta memutus mata rantai penyebaran Covid-19. Maka dari itu, penulis bekerjasama dengan semua pihak terlibat untuk mengadakan program KKN individu dengan memberikan sosialisasi kepada masyarakat terkait Covid-19 dan protokol kesehatan. Program tersebut bertujuan untuk meningkatkan kesadaran masyarakat dalam menghadapi situasi pandemi Covid-19 dan pentingnya menerapkan protokol kesehatan dimulai dari diri sendiri. Selain itu kegiatan KKN Mandiri Universitas Pancasila 2021 bertujuan untuk ikut serta membantu pemerintah dalam menekan laju penularan Covid-19. Untuk mencapai program tersebut, penulis menggunakan tiga metode yaitu, menggunakan metode observasi, dokumentasi dan demonstrasi. Dengan adanya sosialisasi yang dilakukan oleh penulis ini, diharapkan membuat masyarakat terbiasa untuk hidup berdampingan dengan Covid-19, lebih memahami bagaimana bahaya Covid-19 serta lebih meningkatkan kesadaran diri untuk menerapkan protokol kesehatan dimana pun mereka berada.
ABSTRACT
The Covid-19 pandemic has had a wide range of effects on the economy, society, education, and, most importantly, health. Indonesia is a country where the number of instances is steadily increasing. The government must handle the situation in a severe manner, with public awareness as a supporting factor. To inhibit and break the chain of Covid-19 dissemination, all parties must exercise discipline in applying health protocols. As a result, the author works with all parties involved to organize individual KKN programs by educating the community about Covid-19 and health protocols. The program's goal is to raise public awareness about the Covid-19 pandemic and the significance of starting with oneself while implementing health practices. In addition, the Pancasila University Mandiri Community Service Program for 2021 aims to assist the government in reducing the rate of Covid-19 transmission. The author employs three ways to achieve the program's goals: observation, documentation, and demonstration. With this author's socialization, it is hoped that individuals would become accustomed to living alongside Covid-19, gain a better understanding of Covid-19's hazards, and develop self-awareness to implement health procedures wherever they are.
PERHITUNGAN, PENYETORAN, PELAPORAN DAN PENCATATAN PPH PASAL 23 PADA PERUSAHAAN MANUFAKTUR
Authors: Siregar Yopie Sahatua , Susanto Yulius Kurnia 
Published: November 2022

ABSTRAK
Artikel ini memiliki tujuan untuk menganalisis kesesuaian perhitungan, penyetoran, pelaporan dan pencatatan PPh pasal 23 dengan Undang-Undang Nomor 36 Tahun 2008 dan standar akuntansi keuangan pada perusahaan manufaktur. Penelitian ini menggunakan metode deskriptif. Artikel ini menunjukkan bahwa perhitungan, penyetoran, dan pelaporan PPh pasal 23 sesuai dengan Undang-Undang Nomor 36 Tahun 2008. Pencatatan PPh 23 telah sesuai dengan standar akuntansi keuangan.
ABSTRACT
This article aims to analyze the suitability of the calculation, deposit, reporting and recording of Income Tax Article 23 with Law Number 36 Year 2008 and financial accounting standards in manufacturing companies. This research uses a descriptive method. This article shows that the calculation, deposit, and reporting of PPh article 23 is in accordance with Law Number 36 of 2008. The recording of PPh 23 is in accordance with financial accounting standards.
Pengaruh Pelayanan Jasa Clearence In dan Clearence Out Terhadap Waktu Tambat Kapal Bulk Carrier Di PT Buana Indah Gemaca Cabang Cigading Banten
Authors: Wibowo Titis Ari , Dormawaty Roma , Yohanes Darient 
Published: November 2022

Buana Indah Gemaca Cabang Cigading, Banten merupakan perusahan pelayaran yang bergerak dalam bidang pelayanan jasa keagenan kapal asing dimana perusahaan tersebut berperan sebagai Port Agent atau Local Agent
PT. Buana Indah Gemaca Cabang Cigading, Banten memiliki potensi yang sangat besar untuk berkembang pesat dalam pelayanan jasa keagenan kapal. Peningkatan pelayanan jasa keagenan kapal oleh PT. Buana Indah Gemaca Cabang Cigading, Banten diharapkan dapat meningkatkan jumlah kapal motor yang diageninya. Selama ini dalam pelaksanaan pelayanan jasa keagenan oleh PT. Buana Indah Gemaca Cabang Cigading, Banten masih terdapat kendala yang menyebabkan pelayanan jasa yang diberikan belum optimal. Seperti masih lambatnya proses penyelesaian dokumen-dokumen persyaratan untuk clearence, sehingga mengakibatkan kurang optimalnya pelayanan jasa clearence in dan clearence out yang dilakukan oleh PT. Buana Indah Gemaca Cabang Cigading, Banten.
ВПЛИВ МОРФОМЕТРИЧНИХ ПОКАЗНИКІВ ПЛАЦЕНТИ СВІЙСЬКИХ ТВАРИН НА НОВОНАРОДЖЕНИЙ МОЛОДНЯК
Authors: Коренєва Ж. , Роша Л. , Запека І. , Мазуренко Ю. , Гарнаженко Ю. , Шовкопляс І. 
Published: November 2022

Плацента, Placenta – це комплекс тканинних утворень, які мають розвиток з судинної оболонки плода та слизової оболонки матки для зв’язку плода з материнським організмом. Плацента це орган , який забезпечує організм плода киснем, поживними речовинами. Вона перероблює поживні речовини материнського організму ( гемоглобін, білки, вуглеводи) та синтезує нові. В плаценті синтезується біологічно активні речовини, які мають великий вплив на перебіг вагітності, розвиток плода, а у подальшому і на розвиток новонародженого. Плацента у всіх ссавців відіграє дуже важливу роль, а саме забезпечує зв'язок ембріону з материнським організмом. Плацента формується тільки в період вагітності, а важливу роль у її формуванні відіграють - судинна оболонка плоду та слизова оболонка матки. Плацента у кожного виду тварин має свої певні особливості: по-перше, це форма та розмір ділянок контакту судинної оболонки ембріону з тканинами матки самиці; по-друге, рівень розгалуження судинної оболонки ембріону в тканинах матки та її заглиблення в оточуючі тканини матки.
За період вагітності матка значно збільшує свої розміри та вагу, за даними фахівців таке збільшення знаходиться в межах 10-20 разів. Плацента є основним органом завдяки якому ембріон отримує поживні речовини для подальшого росту та розвитку, а також отримує захист від чинників зовнішнього середовища. Від маси та розвитку плаценти залежить також і ступінь розвитку новонародженого молодняку та здатність пристосування до зовнішнього середовища.
Маса плаценти та кількість в ній котіледонів залежить від віку вагітної тварини та маси теляти при народженні. В середньому у корів віком 6-8 років та масі теляти 27-30 кг маса плаценти складає 18,20 ± 2,10 кг, це більше ніж у віці 3-6 років на 22%, збільшується також і кількість котіледонів на 20%. Маса плаценти у свиней породи велика біла збільшується поступово з віком тварини і досягає максимальної маси при 2-3 опоросі. Поступово до 5-6 опоросу маса її знижується, що має негативний вплив на кількість приплоду та розвиток поросят. Зміна маси плаценти може бути пов’язана з поступовим згасанням впливу гормональної регуляції на рівень обміну речовин, дією стрес факторів та в зв’язку з перенесеними захворюваннями.
Estación meteorológica inteligente para control de riego y mitigación de heladas
Authors: Lupercio Novillo Geovany , Macancela Alberto , Tacuri Eduardo , Lupercio Lucia 
Published: November 2022

En la agricultura, el agua es vital para el cultivo. Conocer cuándo regar y cuánto regar se puede responder técnicamente, a partir de datos provistos por estaciones meteorológicas. Estos datos no siempre están disponibles. Además, si bien en el mercado existen controladores de riego, estos no están integrados a las estaciones y son de arquitectura cerrada. Por otro lado, el desarrollo de la electrónica, la disponibilidad de sensores de costo asequible, protocolos, estándares y código abierto, facilitan la integración de componentes de hardware y software. Este trabajo propone un prototipo de estación meteorológica inteligente que provee en tiempo real datos de temperatura, humedad del ambiente, humedad del suelo, lluvia, como entrada para que un controlador active el riego en dos casos: i) por necesidad de agua para el desarrollo del cultivo; o ii) para mitigar heladas, apoyando al desarrollo sostenible agrícola con tecnología local, de código abierto y de costo asequible. Se aplicó la metodología basada en prototipos rápidos, evaluando la operatividad de cada dispositivo electrónico y su integración en ambiente controlado, y luego en una parcela experimental, en la granja Nero de la Universidad de Cuenca. Para el desarrollo se empleó hardware y software de código abierto, utilizando IDE de Arduino y Visual Studio Code. Para energizar se usó un panel solar y baterías, optimizando el consumo energético. Este prototipo ha mostrado un funcionamiento continuo y estable, operando a 3100 m.s.n.m. Se continuará monitoreando y mejorando, para en el futuro poner a disposición de usuario final.
Risk Factors for the Development of Atrial Fibrillation in the Kazakh Patients
Authors: Taizhanova Dana , Bazarova Nazira , Kalimbetova Akerke , Gartung Tatyana , Bodaubay Roza , Muratbekova Shynar , Rustembekkyzy Zhansaya 
Published: November 2022

BACKGROUND: Atrial fibrillation (AF) is the most common persistent heart rhythm disorder.

AIM: Assessment of clinical predictors of atrial fibrillation in the Kazakh population.

METHODS: An analytical clinical and epidemiological study of 75 patients with AF of Kazakh nationality. Descriptive analysis of medical records was carried out and the results of laboratory and instrumental research methods. Statistical analysis was carried out using the Statistica 6.0 Software package from StatSoft Inc. (USA) and MS Excel.

RESULTS: In the majority of the studied patients (86.7%), atrial fibrillation was associated with hypertension, in 49.3% of patients was diagnosed with coronary artery disease. A permanent form of atrial fibrillation was observed in 63%, in 20% AF manifested itself in the form of paroxysms, in 17% AF was persistent. AF, which arose against the background of CHF, was established in 41.3% of the patients studied by us, while a decrease in LVEF below 40% was observed in 21.3% of the examined patients. In our study, diabetes mellitus was diagnosed as a comorbid pathology in 24% of patients and diabetes mellitus correlated with permanent AF in 66.7%. Thyroid pathology was observed in 9.3% cases. CRHD as a concomitant disease occurred in 12% of cases. In 5.7% of cases, AF was registered as idiopathic (primary) without a history of cardiovascular and concomitant pathology. Smoking as a risk factor was observed in 16%, alcohol consumption, was noted by 8 patients (10.7%). In 40% of cases, patients with AF were obese, 45.3% of the patients were overweight (BMI ≥25).
Acute Limb Ischemia among COVID-19 Patients in Hospital Kuala Lumpur
Authors: Aimanan Karthigesu , Ali Nurul Nadiah Nazurah Mohd , Rahman Mohd Nurhisham Azmi Abdul , Pian Putra Mas , Pillay Kumaraguru V.K. , Hayati Firdaus , Hussein Hanif 
Published: November 2022

BACKGROUND: Acute arterial thromboembolism among the novel coronavirus 2019 (COVID-19) patients is worrying as it can result in significant thrombotic events.
AIM: The research aimed to determine the clinical results of COVID-19 infected patients who had ALI (acute limb ischaemia) during the COVID-19 epidemic.
METHODS: ALI patients who had a positive COVID-19 were included in the observational cohort study, which was conducted at a single centre. The primary outcomes were 30 days mortality, limb salvage, and successful revascularization.
RESULTS: From May to October 2021, data from 21 ALI subjects who had positive COVID-19 were analysed. Of the 21 included subjects, 10 were males (48%). Their mean age was 65±5 years. In nine subjects (42%), revascularization was done. Four (19%) of the 21 persons died while they were hospitalized. Twelve patients underwent major amputation and among them, one patient died after a month of hospitalization for COVID-19-related pneumonia. Among the 12 patients that underwent amputation, 10 of them presented with ALI during the first week of COVID-19 illness. Only one patient developed acute limb ischaemia despite being on heparin thromboprophylaxis.
CONCLUSION: Despite attempts at revascularization, ALI-associated with COVID-19 has high mortality and high rates of limb loss. In our experience, major amputation is required in up to a third of patients. This poor result appears to confirm that these infected individuals have a marked hypercoagulable condition. However, adhering to the treatment protocol of heparin thromboprophylaxis confers a benefit in this patient group.
The Effect of Remifentanil, MgSO4, or Remifentanil-MgSO4 as Neuroprotectors on BDNF, MAC, and Caspase-3 Levels in Wistar Rats with Traumatic Brain Injury
Authors: Arianto Ardana Tri , Soetrisno Soetrisno , Purwoko Purwoko , Indarto Dono 
Published: November 2022

BACKGROUND: Traumatic brain injury (TBI) can lead to cell death and neurologic dysfunction. Meanwhile, Remifentanyl is an opioid with potent analgesia, while magnesium sulfate (MgSO4) has antinociceptive properties that can prevent hemodynamic instability during laryngoscopy.

AIM: This study aims to examine the effect of remifentanil, MgSO4 and their combination on BDNF, MAC, and Caspase-3 levels in Wistar rat models with TBI.

METHODOLOGY: An experimental study was conducted on 30 male Wistar rats which were randomly divided into five groups. The control group (G1) received normal saline, the induced group (G2) received normal saline after TBI induction using the modified Feeney method, and the treated group (G3, G4, and G5) received remifentanil, MgSO4, and their combination after TBI induction. The rats’ brain tissues were analyzed for BDNF, MAC, and Caspase-3 levels using ELISA. The data were analyzed statistically with ANOVA followed by post hoc Multiple Comparison Test (p < 0.05).

RESULTS: Treatment with remifentanil, MgSO4 or the combination of both in TBI subjects reduced MAC and Caspase-3 but increased the BDNF level. The post hoc multiple comparisons showed significant differences in all groups except groups 3 and 5 in terms of MAC (p = 0.190) and Caspase-3 (p = 0.999). The combination of remifentanil-MgSO4 increased BDNF levels significantly.

CONCLUSION: The administration of remifentanil, MgSO4 , or their combination can serve as a neuroprotector in Wistar rat models with TBI by lowering MAC and Caspase-3 as well as increasing BDNF levels.
Fredric Jameson, National Allegory, and the Theory Anxiety in China
Authors: Wang Xiteng 
Published: November 2022

Cet article explore le phénomène de l’hybridation de la reconnaissance de soi dans la littérature de la fin du XX e siècle en Chine. Plus précisément, il se concentre sur la théorie de « l’allégorie nationale » de Fredric Jameson, l’une des théories les plus influentes de la Chine de la fin du XX e siècle. Inspiré de la Qiao Yiology, cet article met en lumière l’impact de la théorie de l’« allégorie nationale » de Fredric Jameson dans le contexte de la « High Theory Wave » de la théorie littéraire chinoise dans les années 1990. L’incommensurabilité liée à l’intraductibilité du concept « d’allégorie nationale », ce concept « mal traduit », à laquelle s’ajoute l’interprétation nouvelle de la littérature et de la culture du « Tiers monde » a profondément affecté la transformation du paradigme du discours académique chinois contemporain. Bien que cette transformation n’ait pas changé l’anxiété relative à l’identité culturelle chinoise, les nouvelles théories comme celles de la Qiao-Yiologie indiquent une manière possible d’envisager les principes généraux et les lois communes de la création littéraire.