bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pulsed laser-assisted synthesis of nano nickel(ii) oxide-anchored graphitic carbon nitride: Characterizations and their potential antibacterial/anti-biofilm applications
Authors: Baig Umair , AbuMousa Rasha A. , Ansari Mohammad Azam , Gondal Muhammad A. , Dastageer Mohamed A. 
Published: November 2022

Abstract
Nickel(ii) oxide-graphitic carbon nitride (n-NiO@g-C3N4) nanocomposite, in which nickel oxide nanoparticles (n-NiO) are anchored on the polymeric surface of graphitic carbon nitride (g-C3N4), was synthesized using the pulsed laser post processing (PLPP) in liquid medium. In the PLPP method, the precursors (NiO and g-C3N4) were simultaneously subjected to pulsed laser-induced fragmentation, and pulsed laser-induced defect engineering (anchoring of NiO on g-C3N4). To optimize the functionality of the material, n-NiO@g-C3N4 with four different mass contents of n-NiO was synthesized. The synthesized n-NiO@g-C3N4 nanocomposite and its composite partners (n-NiO and g-C3N4) were structurally, morphologically, elementally characterized by X-ray diffraction, filed emission scanning electron microscope, transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) analyses. As a first anti-microbial application, n-NiO@g-C3N4 was used to evaluate the minimal inhibitory concentration and minimal bactericidal concentration against the gram-positive Staphylococcus aureus and gram-negative Pseudomonas aeruginosa bacteria. As a second anti-microbial application, the efficacy of n-NiO@g-C3N4 nanocomposite to retard S. aureus and P. aeruginosa biofilms’ growth was evaluated. It was found that for both applications, n-NiO@g-C3N4 nanocomposite exhibited an excellent anti-bacterial activity compared to pure g-C3N4.
Association between plasma total homocysteine (tHcy) and strokes: A meta-analysis
Authors: Li Hang , Shu Lingfeng , Dai Qinghai , Wu Tao 
Published: November 2022

Abstract

Objective
Inconsistent findings have been reported regarding the association between elevated plasma total homocysteine (tHcy) and the risk of different types of strokes. We conducted this meta-analysis to identify the association between tHcy and different kinds of strokes or recurrences of strokes, and provide evidence for preventing.

Methods
Relevant studies published before May 1, 2022 in databases such as PubMed, EMBASE, the Cochrane Library, CNKI, and Wanfang were retrieved. Two researchers independently searched and extracted the data, and used Stata 16.0 statistical software for analysis. Results were presented as the odds risk (OR) and the corresponding 95% confidence intervals (CI).

Results
In total, 24 articles were included, involving 51,426 subjects, of which 4,983 had stroke events during follow-up. Relative to lower tHcy, higher tHcy were associated with increased stroke (OR = 1.95, 95% CI: 1.59–2.37), ischemic stroke (OR = 1.71, 95% CI: 1.39–2.11), hemorrhagic stroke (OR = 1.99, 95% CI: 1.03–3.84), and recurrent stroke (OR = 1.25, 95% CI: 1.12–1.39), respectively.

Conclusions
This study shows that elevated tHcy increases the risk of stroke, including ischemic stroke and hemorrhagic stroke, and is closely related to the recurrence of stroke. It is recommended to pay attention to the detection of tHcy in the management of stroke patients in the future, and take effective measures to prevent and delay the progression of stroke.
Fabrication of ultra-sensitive carbon paste electrode with nanocomposite CdS modification for electroanalysis of rafoxanide in dosage form and biological fluids
Authors: Salem Waheed M. , Abdel-Lateef Mohamed A. , Abdel Hamid Mohamed A. , Batakoushy Hany A. 
Published: November 2022

Abstract
An anthelmintic, rafoxanide (RF), is frequently used in veterinary medicine to cure fascioliasis in cattle and sheep. A sensitive, quick, and selective detection of RF in its pharmaceutical preparation and in human urine was achieved through developing a new electrochemical sensor. The suggested method relied on the electro-oxidation of RF that used a modified carbon paste electrode in the presence of sodium dodecyl sulfate, which acts as an anionic surfactant. Voltammetric types were utilized in RF analysis, and these methods were cyclic voltammetry and differential pulse techniques. The suggested electro-analytical method’s validity is verified using the International Council on Harmonization (ICH/Q2) rules. The calibration curve for RF quantification was done in the concentration range from 2.9 × 10−6 to 3.1 × 10−4 M at cadmium sulfide modified carbon paste electrode. The limit of detection and the limit of quantification LOQ were found to be 6.7 × 10−7 M and 2.01 × 10−6 M, respectively. This study could be applied to the examined drug in QC-laboratory units, and also RF could be assayed in its pharmacokinetic studies.
The Effect of Ownership Structure on the Value of a Private Company
Authors: Van den Cruijce Johan , Baffert II Gamble , Janssens de Bisthoven Nicolas , Tistaert Jurgen 
Published: November 2022

Abstract
The value of an unlisted company is a contentious issue. This is because investors value marketability and liquidity, but vacillate on the appropriate percentage discount that needs to be applied for the valuation of a private company. As more companies find it easier to remain private, a better understanding of this discount is increasingly important. The extant discount studies are mainly derived from financial and transactional data. They provide reliable averages using large sample sizes, but present few determinants to explain the wide ranges in the observations. Our research is based on a unique, alternative data source that complements existing studies by tapping into rich contextual information. Specifically, we examine court decisions that determine the appropriate discount and relate this percentage to an important characteristic of a private company: its “open” character, i.e. its willingness to accept outside shareholders or partners in the venture. We find that open and closed companies differ in value 6.5%. Our conclusions hold after controlling for known determinants of the discount. Our results impact valuation approaches and present real-world application for the owners and managers of private companies who may consider opening ownership to third parties.
The Readiness Potential Correlates with Action-Linked Modulation of Visual Accuracy
Authors: Benedetto Alessandro , Ho Hao Tam , Morrone Maria Concetta 
Published: November 2022

AbstractVisual accuracy is consistently shown to be modulated around the time of the action execution. The neural underpinning of this motor-induced modulation of visual perception is still unclear. Here, we investigate with EEG whether it is related to the readiness potential, an event-related potential (ERP) linked to motor preparation. Across 18 human participants, the magnitude of visual modulation following a voluntary button press was found to correlate with the readiness potential amplitude measured during visual discrimination. Participants’ amplitude of the readiness potential in a purely motor-task was also found to correlate with the extent of the motor-induced modulation of visual perception in the visuomotor task. These results provide strong evidence that perceptual changes close to action execution are associated with motor preparation processes and that this mechanism is independent of task contingencies. Further, our findings suggest that the readiness potential provides a fingerprint of individual visuomotor interaction.
List of the genera of Stratiomyidae (Diptera: Stratiomyiomorpha) from Colombia based on biological collection records and literature
Authors: Torres-Toro Juliana , Grisales Diana , Wolff Marta 
Published: November 2022

The Stratiomyidae fauna of Colombia is not well known, mainly because of very few published studies for the country. Currently, 35 genera are recorded. A review of the literature and the examination of more than 4000 specimens from entomological collections allowed us to record 54 genera of Stratiomyidae in Colombia, adding 19 genera to the previously known. A list of genera currently reported, an image of the wing for most of these genera, and locality data, are included.
Hábitos de compra y consumo de alimentos durante las cuarentenas por COVID-19 en Bogotá
Authors: Acevedo-Navas Christian , Osorio-Romero María Angelica 
Published: November 2022

La pandemia por covid-19 ha generado implicaciones en diversos ámbitos, incluido el comportamiento de los consumidores. Uno de los primeros renglones de consumo afectados ha sido el de los alimentos, debido a su demanda como bien fundamental para la subsistencia. En este artículo se analizan los principales cambios en los hábitos de compra y consumo de alimentos durante las cuarentenas por covid-19 en Bogotá. Para esto, se planteó un diseño cuantitativo, no experimental de campo, en el que participaron 506 estudiantes universitarios. Los hallazgos muestran que durante las cuarentenas aumentaron las conductas de consumo relacionadas con la permanencia en casa, como las compras en línea, la cocción y consumo de alimentos en casa, y la importancia de la logística y las estrategias digitales. Se definieron tres tipologías de consumidores: i) quienes mostraron mayor cambio en sus hábitos durante las cuarentenas, ii) quienes mantuvieron hábitos relativamente semejantes que antes de la pandemia y iii) quienes siguieron hábitos fuera de casa a pesar de las cuarentenas. Finalmente, el presente estudio busca ofrecer una perspectiva que aporte a la comprensión del comportamiento del consumidor y sus cambios durante y a partir de la covid-19, más allá de la relación hábitos de consumo de alimentos-salud, que ha sido la perspectiva dominante en la literatura existente.
The Role of Platelet-Derived Growth Factor in Focal Segmental Glomerulosclerosis
Authors: Jia Ting , Xu Tong , Smeets Bart , Buhl Eva Miriam , Moeller Marcus Johannes , Floege Jürgen , Klinkhammer Barbara Mara , Boor Peter 
Published: November 2022

Significance Statement
We investigated the role of the profibrotic PDGF in the development and progression of FSGS in a murine model resembling human FSGS. Injured podocytes expressed PDGF-B, inducing parietal epithelial cell activation, proliferation, and a profibrotic switch–driving FSGS. Therapeutic inhibition of PDGF-B significantly reduced proteinuria and FSGS, suggesting that inhibition of the PDGF signaling pathway might be a potential novel treatment for patients with FSGS.

Background
FSGS is the final common pathway to nephron loss in most forms of severe or progressive glomerular injury. Although podocyte injury initiates FSGS, parietal epithelial cells (PECs) are the main effectors. Because PDGF takes part in fibrotic processes, we hypothesized that the ligand PDGF-B and its receptor PDGFR-β participate in the origin and progression of FSGS.

Methods
We challenged Thy1.1 transgenic mice, which express Thy1.1 in the podocytes, with anti-Thy1.1 antibody to study the progression of FSGS. We investigated the role of PDGF in FSGS using challenged Thy1.1 mice, 5/6 nephrectomized mice, Col4−/−
(Alport) mice, patient kidney biopsies, and primary murine PECs, and challenged Thy1.1 mice treated with neutralizing anti–PDGF-B antibody therapy.

Results
The unchallenged Thy1.1 mice developed only mild spontaneous FSGS, whereas challenged mice developed progressive FSGS accompanied by a decline in kidney function. PEC activation, proliferation, and profibrotic phenotypic switch drove the FSGS. During disease, PDGF-B was upregulated in podocytes, whereas PDGFR-β was upregulated in PECs from both mice and patients with FSGS. Short- and long-term treatment with PDGF-B neutralizing antibody improved kidney function and reduced FSGS, PEC proliferation, and profibrotic activation. In vitro, stimulation of primary murine PECs with PDGF-B recapitulated in vivo findings with PEC activation and proliferation, which was inhibited by PDGF-B antibody or imatinib.

Conclusion
PDGF-B–PDGFR-β molecular crosstalk between podocytes and PECs drives glomerulosclerosis and the progression of FSGS.
Pivoting the Profession as We Approach the Quasquicentennial
Authors: Menon Goutham M. , Mondros Jacqueline , Smyth Nancy J. , Teasley Martell , Hostetter Carol 
Published: November 2022

The year 2023 marks professional social work’s quasquicentennial: the 125th anniversary of our profession since the first social work classes were offered in the summer of 1898 at Columbia University. The profession has grown in its reach across many human service sectors over all these years creating opportunities for those who want to serve their communities in myriad and impactful ways. As we observe disruptions in the higher education sector, with profound implications to the mission of the social work profession, we are also witnessing many cross-sector opportunities for the future of the social work profession. Given our changing environment, the time is right for us to re-envision social work education and practice in ways that center our professions’ commitment to social justice and the well-being of individuals, families, and communities. In our efforts to meet the needs of the people and communities we serve, we have seen several innovative and impactful expansions into areas that have augmented our original “scope of practice.” Some have occurred to meet the needs of the time; others have morphed due to market conditions for jobs that have been encroached on by other professions/disciplines. And as we see more complex and vexing societal issues in our current environment, it is time for us to collectively discern our purpose, adjust our mindset, and be prepared to meet future challenges and opportunities. This special issue on “re-envisioning social work” provides a space for thought leaders to showcase meaningful and purpose-filled advances for the profession.
Relationship of Variables with Student Performance in Distance Professional Education
Authors: Dalcin Eduardo , Abegg Ilse , Ceretta Paulo Sergio 
Published: November 2022

This research aims to analyze the relationship between interaction, interactivity, student attributions and quality of life, teacher attributions and the performance of EaD/IFFAR students. As a research methodology, action research was used. In the 1st Cycle (Diagnostic Action Research), the studies generated evidence that EaD/IFFAR students are characterized as an adult audience, most of them female, male students have a higher average of digital literacy, while female students have better performance. In the 2nd Cycle (Discipline Intervention), it was observed that in the discipline that received the intervention process, students presented the highest levels of interaction and performance. And, at the end of the 3rd Cycle (Definition of the Structural Model), the research objective was confirmed, which relates the Student Attributions to their school performance. In addition to having a direct and positive relationship, it recorded the highest coefficients of explanation (R²), containing the highest index of the model, being classified as moderate and significant. It is also noteworthy that the relationship between the variable Student Attribution and Performance was the one that registered the greatest effect in the research, being also classified as having a moderate effect.

Keywords: Distance professional education. Moodle. Distance education student attributes. Distance Education Student Performance.
Issues in teaching the human and ecology concept
Authors: Gulmira Mussinova , Kuralay Tulebayeva , Doskeyeva Shaiza , Zhanar Aitova , Sekey Zhanbota 
Published: November 2022

The purpose of this research is to evaluate the problems encountered in teaching the concept of human and ecology from the perspective of primary school teachers. The research was created in accordance with the qualitative research method. The study group of the research consists of 25 primary school teachers who are teaching in various primary schools in Kazakhstan in the 2022–2023 academic year. Research data were collected with a semi-structured interview form developed by the researchers. The research data were analysed by descriptive analysis method. As a result of the research, the majority of primary school teachers who participated in the research stated that they found the students' knowledge of human and ecology concepts at a moderate level. Majority of the primary school teachers who participated in the research stated that the students' interest in the concepts of human and ecology was high. The primary school teachers who participated in the research expressed the lack of materials, the inability to find the opportunity to practice, the lack of opportunity to develop projects, the inadequacy of cooperation with the family, the difficulty in sensitising the students and the inadequacy of the ecological infrastructure of the schools as the problems they encounter while teaching the concepts of human and ecology to their students.

Keywords: Human and ecology, concept teaching, primary school teachers
Investigation gender difference towards science process skills (SPS) using problem based learning
Authors: Darmaji Darmaji , Astalini Astalini , Kurniawan Dwi Agus , Chen Diki , Wirayuda Ricky Purnama , Winda Febrina Rosa 
Published: November 2022

Physics education students as prospective educators have the task of building student knowledge. This requires physics education students to master SPS because most physics lessons emphasize activity-centered material. The research conducted aims to analyze the level of mastery of SPS in the Melde practicum in terms of gender. This research involves practical activities by applying a problem-based learning model (PBL). This study uses total sampling with participants being first year physics education students class 2019/2020 consisting of 19 male students and 76 female students at Jambi University with sampling technique used is total sampling. The analytical technique used in this study is descriptive statistics with data collection assisted by observation sheets aimed at measuring students' SPS. The results showed that female students had better SPS than male students as indicated by the average score. These results indicate that girls tend to be more active in doing practicum, this tendency arises as a result of a strong curiosity fromthe students themselves
Keywords: Physics, SPS, problem based learning, melde practicum, gender
Pump Schedule Optimization for Hydraulic Fracturing of a Single Fracture
Authors: Bailey William J. 
Published: November 2022

Summary
This paper presents a generalized methodology for hydraulic fracturing pump schedule (PS) optimization to maximize a stated objective function. The methodology is illustrated using an example where the objective function of interest is return on investment (RoI) of a single planar fracture in a horizontally layered tight gas reservoir. The method considers both deterministic optimization and optimization under uncertainty with a stepwise solution and the core algorithms described. The resultant PS is operationally realizable, and the results are compared against a base case.
Diagnostic value of spiral CT energy spectrum imaging in pathological differentiation of colorectal cancer
Authors: Li， Ze-mao , Shi， Qian-qian , Feng， Li , Wang， Xing-wen , Zhou， Wei , Zhang， Hui-ying , Chen Wei-bin 
Published: November 2022

Abstract
Objective: To investigate the accuracy of CT energy spectrum imaging in predicting preoperative pathological differentiation of colorectal cancer patients.
Methods: From 2019 September to 2021 November, a retrospective study was performed for the eighty-two patients with colorectal cancer through preoperative colonoscopy or surgical pathology confirmed in our hospital. According to the pathological results, the patients were divided into middle and high differentiation group (62 cases) and low differentiation group (20 cases). GE Revolution CT scanner was used to scan the patients with energy spectrum imaging, in the arterial and venous phase, it measured and recorded the single energy CT values from 40kev to 140kev and various energy spectrum parameters of lymph nodes around the lesions. And statistically analyze the above indices.
Result: In arterial phase: the single energy CT values from 40kev to 140kev in the low differentiation group were higher than those in the medium and high differentiation group (all P <0.05); IC(Iodine concentration), NIC(Normalized iodine concentration) and λ(the slope of the energy spectrum curve) of colorectal cancer in low differentiation group were higher than that in medium and high differentiation group(all P<0.05). The ROC (receiver operating curve) showed that the AUC (area under the curve) of the single energy CT values from 40kev to 140kev were less than 0.800. The AUC of IC and NIC were 0.800 and 0.828 respectively; the highest AUC of the combination of IC and NIC was 0.850. In venous phase: the single energy CT values from 40kev to 130kev in the low differentiation group were higher than those in the medium and high differentiation group(all P<0.05), and IC, NIC, λ and Eff-Z(Effective-Z) of colorectal cancer in low differentiation group were higher than that in the medium and high differentiation group(all<0.05). The ROC curve showed that the AUC of the single energy CT values from 40kev to 90kev were higher than 0.800. The AUC of IC, NIC, λ and Eff-Z were 0.927, 0.882, 0.859 and 0.863 respectively; the parameters were combined in pairs, IC and λ achieved the highest AUC, and the highest AUC was 0.934. Three parameters were combined, IC, NIC and λ achieved the highest AUC, and the highest AUC was 0.942, the combined AUC of the four was 0.943. Compared with the arterial phase, the single energy CT values from 40kev to 90kev and energy spectrum parameters in venous phase had better diagnostic efficacy in predicting different degrees of differentiation of colorectal cancer.
Conclusions: Parameters of energy spectrum CT imaging can better predict the differentiation grade of colorectal cancer before operation and provide imaging basis for clinicians.
Impact of SARS-CoV-2 on Hemodialysis Among Medicare Beneficiaries in Five Northeastern States, January 2019-December 2020
Authors: Andes Linda , Nelson Christina A. , Pavkov Meda E. , Burrows Nilka Ríos , Novosad Shannon A. , Armstrong Paige A. , Kulkarni Aniket D. 
Published: November 2022

Abstract

Background: The COVID-19 pandemic in the United States is on-going and has impacted healthcare practices substantially. Consistent access to healthcare and, particularly, dialysis services are essential to the management of end stage renal disease (ESRD). The objective of this analysis was to examine patterns of outpatient hemodialysis utilization and outcomes of ESRD and COVID-19 in the 5 states with highest incidence of COVID-19 during the early stages of the pandemic.
Methods: We used data from the Centers for Medicare and Medicaid Services (CMS) to examine trends in receipt of outpatient hemodialysis in 2019 and 2020 among Medicare beneficiaries with fee-for-service (FFS) coverage.
Results: We found that average monthly hemodialysis rates for beneficiaries with ESRD without COVID-19 were stable over time at average monthly rates of between 2.5 and 2.8 sessions per person per week in both 2019 and 2020. Beneficiaries with COVID-19, both with and without pre-existing ESRD, had hemodialysis rates that varied monthly with an average of 2.5 sessions per week per person. Adjusted death rates were highest among beneficiaries with COVID-19 and pre-existing ESRD, followed by beneficiaries with COVID-19 and no pre-existing ESRD. There was little within-group variation in hemodialysis utilization by race/ethnicity but age- and sex- adjusted death rates varied considerably by racial and ethnic group.
Conclusions: Dialysis facilities were able to provide hemodialysis sessions at typical rates despite challenges during the COVID-19 pandemic. However, patients with ESRD who contracted COVID-19 had remarkably high death rates, highlighting the need for ongoing efforts to protect at-risk populations from COVID-19.