bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Smoking on Family Functions
Authors: NURLU USLU Dilek , ARSLAN İsmail , USLU Sadettin , GÜLMEZ Gülay , DEMİR Şevin , TEKİN Oğuz 
Published: October 2022

Aim: Family is the most natural environment where people can meet their needs of love, compassion, affection and care for mental and physical health. In this study, we aim to investigate the relation between smoking and family functions.
Material and Method: Ninety seven patients between 18-60 years age who were admitted to the Ankara Training and Research Hospital, live with at least one family member and agreed to participate in the study were included in this study. Cross-sectional, observational and analytic methods were applied. The recorded data of the participants were as follows: age, sex, occupation, marital status, education level, the family members whom living with, the status of smoking at home, chronic diseases and current medication. McMaster Model of Family Functioning (MMFF) and Fagerström Test for Nicotine Dependence (FTND) were used.
Results: Statistically significant differences between MMFF scores of smoking patients in the subscales of “Roles” and “Affective Involvement” were found (p=0.004, p= 0.002, respectively). We have seen in the subscale of “Problem Solving” that single members were negatively affected (p=0.033). The negative effects of smoking were found to be decreasing by age in the “Communication” subscale (p=0.002). The “Roles” subscale was observed to be negatively disturbed in the group of smokers with chronic diseases(p=0,050). We also found that being single and having a chronic disease negatively affected “Affective Responsiveness” subscale (p=0.050, p=0.020, respectively).
Conclusion: Smoking affects the family functions negatively. Thus, the fight against smoking might be thought to make a favorable effect on the family functions.
Analysis of the Premarital Health Examinations Results of Family Physicians in Isparta: A Retrospective Study
Authors: ÜNVER Şerife , İŞCAN Gökçe , YILDIRIM BAŞ Funda 
Published: October 2022

Aim: Family physicians, who are the primary providers of health care also perform a premarital examination, which is included in preventive services and required to ensure the continuation of healthy generations. This study was conducted to raise awareness and assess the current situation by analyzing the results of premarital examinations in the province of Isparta.
Material and Method: This is a retrospective, epidemiological, analytical study. The data of 16.181 people who applied to family health centers in Isparta provinces and districts for any reason between the years 2017-2020, were analyzed retrospectively.
Results: As a result of retrospective examination and analysis of premarital examination data of 16.181 people between 2017 and 2020, the average age was 29.70±8.70, VDRL-RDR was found in 0.2% of the individuals, TPHA in 0.1%, HBsAg in 0.9%, Anti-HBcIgM in 0.03%, Anti-HCV in 0.4%, and Anti-HIV positivity was not detected. Anemia was found in 3.5% of the individuals, and thalassemia carrier was found in 2.2%.
Conclusion: Examinations in the family in the province of Isparta will also be completed in close proximity to family physicians, and premarital examination will be performed. In the training, detailed information was given about emphasizing the repetition of premarital examination by physicians.
NEUROPLASTICITY AFTER COCHLEAR IMPLANTATION AS ASSESSED BY THE PLASMA LEVEL OF MMP-9 AND ITS GENETIC POLYMORPHISMS: A PROSPECTIVE STUDY OF CONGENITALLY DEAF CHILDREN
Authors: Matusiak Monika , Oziębło Dominika , Ołdak Monika , Rejmak Emilia , Kaczmarek Leszek , Skarżyński Henryk 
Published: October 2022

BackgroundIf it was possible to assay biomarkers of neuroplasticity it might facilitate clinical management of deaf implanted children by identifying those among them who are at risk of speech and language rehabilitation failure. <i>MMP9</i> is a proteinase involved in neuroplasticity underlying different clinical conditions in human.Material and methodsThis was a longitudinal, prospective cohort study of 61 congenitally deaf children who underwent cochlear implantation. We investigated the genetic variants of matrix metalloproteinase 9 (<i>MMP9</i>) and plasma levels of MMP-9 that have been implicated in
neuroplasticity after cochlear implantation. Auditory development was assessed by using the LittlEARS Questionnaire (LEAQ) at three follow-up points and the plasma level of MMP-9 was measured at implantation.ResultsThere was a significant negative correlation between MMP-9 plasma level at implantation and LEAQ score at 18 months follow-up (<i>p</i> < 0.05). Two clusters of good and poor CI performers could be isolated based on this correlation. The prevalence of genetic variants of MMP9 – rs3918242, rs20544, and rs2234681 – in the good performers cluster was different to their prevalence in the poor performers cluster.ConclusionsThe study showed that children born deaf who have an MMP-9 plasma level of less than 150 ng/ml at cochlear implantation have a reasonable chance of attaining a high LEAQ score after 18 months of speech and language rehabilitation. It appears that MMP-9 plasma level at cochlear implantation is a promising prognostic marker for CI outcome.
The History of Pupillography and Possibility of Its Using in Modern Ophthalmology
Authors: Sakhovskaya N. A. , Frolov M. A. , Kazakova K. A. , Kolodkina M. G. 
Published: October 2022

Nowadays medicine has great opportunities for a detailed study of organs and systems, quick and accurate diagnosis of norm or pathology. Many diagnostic procedures are universal and are used by doctors of different specialties. Pupillography is a method of studying pupillary reactions, which is based on registering changes in its magnitude by photographing or filming. This study has found wide application in many areas of medicine, such as ophthalmology, neurology, narcology, general medical practice, for the diagnosis of different pathological conditions.Currently, in all areas of medicine, preference is given to objective diagnostic methods. In our country, much attention is paid to the development and introduction into medical practice of new technologies and minimally invasive research methods which purpose is timely accurate diagnosis and effective treatment of various diseases. The visual analyzer transmits visual information to the center of the parasympathetic division of the autonomic nervous system, which is responsible for the work of the sphincter of the pupil and to the center of the sympathetic division, which is responsible for the work of the dilatator. In the pathology of the visual organ, there is a violation of the correctness of information transmission, which can be used for basic research not only in ophthalmology but also in other specialties. Science and technology provides opportunities for ultra-thin, specific diagnostics and monitoring of various physiological and pathological states of organs and systems, the results of which are taken into account in many analyzing programs of the latest devices. Therefore, the importance of studying pupillary reactions is of great interest for many areas of medicine, and more specific studies can improve the accuracy of the diagnosis. This article describes the history of the development of pupillometric and pupillographic methods of research from the middle of the XVIII century and till modern devices. The importance of the study of pupillary reflexes for assessing the state of the visual analyzer and the possibility of using chromatic pupillometry is discussed, the main indicators of the pupillomotor system and their norms are given. Pupillometry provides the ability to accurately quantify changes in pupil size for clinical and research purposes.
Correction of Ametropia in Patients with Posterior Elevation of the Cornea
Authors: Eskina E. N. , Parshina V. A. , Movsesyan M. Kh. , Malakhova A. V. 
Published: October 2022

Purpose: to evaluate the effectiveness of ametropia correction in patients with posterior corneal elevation but without signs of subclinical keratoconus, based on postoperative results of transepithelial photorefractive keratectomy (Trans PRK).Patients and methods. A retrospective comparative study was conducted to analyze the results of surface ablation, which was performed using transepithelial photorefractive keratectomy in 18 patients with posterior corneal elevation (36 eyes). The control group included 18 patients with eyes without these changes (36 eyes). Both groups were comparable in age, gender and refraction. Demographic data, pre- and postoperative refraction, NCOSIS and ICOSIS, maximum ablation, I/S ratio index, central corneal thickness, anterior and posterior keratometry, Biaocci-Versachi index for anterior and posterior surfaces, RMS (mk/mm2) in standard deviation, the highest elevation point of the posterior surface of the cornea — KVB (microns), index of asymmetry of tangential curvature of anterior and posterior were determined and analyzed in all patients the surfaces are SIF (D) and SIB(D), which determines the vertical asymmetry in the upper and lower hemispheres of the cornea.Results. Observations of the dynamics of these parameters were carried out for 12 months after surgery for patients of both groups, and showed that the conclusion of Trans PRK in patients with posterior corneal elevation leads to similar refractive results compared with normal eyes. The safety and effectiveness indicators for both groups were also comparable. Significant differences in the speed of vision restoration between the groups were revealed, which is manifested by significant differences in visual acuity indicators within 1 month after surgery, but by 1 year the differences are leveled. It was determined that the effectiveness of astigmatism correction in the group with posterior elevation was significantly lower. The refractive results in the elevation group were good. During the observation, there was no pronounced dynamics of the indicators of elevation of the posterior surface of the cornea.Conclusion: the method of transepithelial photorefractive keratectomy can be recommended for the treatment of ametropia in patients with posterior corneal elevation, but without signs of subclinical keratoconus, however, the development of additional nomograms is required in order to increase the predictability of laser vision correction in patients of this category.
The Results of Studying Spatial Perception in Children with Ophthalmopathology Using the Technique of Copying Taylor’s and Rey–Osterrieth’s Figures
Authors: Rychkova S. I. , Likhvantseva V. G. , Sandimirov R. I. 
Published: October 2022

The work is devoted to one of the actual problems of ophthalmology — the study of spatial perception in children with ophthalmopathology.Purpose of the work is to study the characteristics of spatial perception in children with ophthalmopathology using the technique of copying Taylor’s and Rey–Osterrieth’s figures.Patients and methods. 284 children aged 6 to 8 years were observed: 1) 135 children with operated convergent non-paralytic strabismus; 2) 53 children with organic pathology of the retina and optic nerve; 3) 96 children of the control group (without ophthalmopathology). The characteristics of spatial perception were evaluated according to the results of copying complex geometric figures — Taylor’s (with a right hand) and Rey–Osterrieth’s (with a left hand).Results. It is found that the distinguishing particularities of the group of children with non-paralytic strabismus are the smaller number of children copying the figures starting from the whole contour (using a deductive strategy) and the reduced quality of drawing compared to those in the group of children without ophthalmopathology. It is also shown that in children with organic ophthalmopathology these features relate to copying Rey–Osterrieth’s figure to a greater degree than copying Taylor’s figure, which may reflect a shift in interhemispheric relations in them towards more pronounced left-hemisphere activity.Conclusion. Thus, the method used in the work is informative, allows to identify the features of spatial perception in children with different ophthalmopathology and conduct a comparative analysis of its characteristics.
Polymerase Chain Reaction in the Management of Patients with Anterior Ophthalmoherpes: a Comparative Study of the Effectiveness of Clinical Use
Authors: Chernakova G. M. 
Published: October 2022

Patiens and methods. We observed 111 patients with various forms of prolonged herpetic keratitis and inflammatory ENT pathology. All patients underwent a study of biological secretions (tear, saliva, blood and urine) for the presence of DNA of herpetic viruses by PCR, systemic antiviral therapy was prescribed. All patients underwent a standard otolaryngological examination, СТ scan of the paranasal sinuses (if necessary), microbiological study of nasopharynx swabs. Local therapy of herpetic keratitis included anti-inflammatory and antibacterial components.Results and discussion. Isolated sinus infalanmmation occurred in 59 % of cases (65 patients), in 38 % of cases (42 patients) there were variants of combinations of sinus inflammation (sinusitis, sphenoethmoiditis, pansinusitis). In 24 % of those included in the study (n = 27), during examination, in addition to the presence or absence of sinusitis, chronic tonsillitis was determined. In 30 % of cases (more often than in other secrets), herpetic viruses were detected in saliva, coccal flora dominated in swabs from the nasopharynx. A marked reduction in ophthalmological symptoms correlated with start of ENT therapy.Conclusions. This clinical and laboratory study showed a close pathogenetic relationship of anterior ophthalmic herpes and concomitant inflammatory pathology of the paranasal sinuses and oropharynx. Active etiotropic therapy of sinusitis and tonsillitis promotes short-term reduction of ophthalmic symptoms.
First Results of Clinical Application of Ultraviolet Corneal Collagen Crosslinking in the Treatment of Corneal and Graft Ulcers in Children
Authors: Pleskova A. V. , Katargina L. A. , Iomdina E. N. , Panova A. Yu. , Mamakaeva I. R. , Zaiceva A. A. , Sorokin A. A. 
Published: October 2022

Ulcerative lesions of the cornea and graft in children are a serious problem in pediatric ophthalmology, leading to serious consequences, up to the anatomical death of the eye. The problem of effective treatment of this pathology and corneal tissue regeneration in children remains relevant, despite the large arsenal of drugs. Recently, ultraviolet (UVA) corneal collagen crosslinking has been proposed as an alternative treatment for corneal ulcers in adults. RASK-CXL is the official name used exclusively for crosslinking in cornea inflammatory diseases. In children, corneal collagen crosslinking is still used only for the treatment of keratoconus. We were the first to use this method to treat corneal ulcers and graft ulcers in children.Purpose: to analyze the results of treatment of ulcerative corneal lesions and graft in children using a new device for local UVA crosslinking.Material and methods. For dynamic observation of patients, biomicroscopy with a fluorescein test, photo registration and optical coherence tomography of the eye anterior part were used. The procedure of local UVA crosslinking for the treatment cornea ulcerative lesions was carried out using a new device on the basis of the permission of the Ethics Committee of the National Medical Reseach Center of eye deseases named after Helmholtz of the Ministry of Health of Russia (protocol No. 56 of 21.10.2021).Results. The use of 3–5 procedures of local UVA exposure (against the background of instillations of 0.1 % riboflavin solution) lasting 5–7 minutes with an interval of 1-3 days ensured epithelization of the cornea and the graft and increased visual acuity in children.Conclusion. The first treatment results of corneal ulcers and graft in children using a new portable device for local UVA crosslinking have shown its high therapeutic efficiency and prospects for further use in clinical practice.
Left Atrial Strain as a Predictor of Diastolic Stress Test Results in Patients With Arterial Hypertension
Authors: Mazur E. S. , Mazur V. V. , Bazhenov N. D. , Nilova O. V. , Nikolaeva T. O. 
Published: October 2022

Aim To study a possibility of using the left atrial strain (LAS) for predicting results of the noninvasive diastolic stress test (DST) in patients with arterial hypertension (AH).Material and methods The study included 98 patients previously diagnosed with AH. As a part of evaluation for complaints of dyspnea, palpitation or pain in the area of the heart, DST and transthoracic echocardiography were performed. Echocardiography included measurements of LAS in the reservoir phase, left atrial volume index (LAVI), pulmonary artery systolic pressure (PASP), and ratio of early filling transmitral flow velocity to mitral annular velocity (Е / е’).Results The DST was negative in 52 patients (group 1) and positive in 46 patients (group 2). Group 2 had greater values of mean Е / е’ (11.0 [9.4; 12.6] vs 9.0 [7.9; 11.1], р=0.0003); LAVI (33.8 [29.0; 40.0] ml /m2 vs 28.0 ml /m2 [25.0; 32.9], р=0.0001); and PASP (29.0 mm Hg [28.0; 30.0] vs 26.0 mm Hg [25.0; 28.0], р<0.0001 were greater, but LAS values were lower (19.0 % [18.0; 21.0] vs 24.0 % [22.0; 28.0], р<0.0001. The predictive capability of LAS with respect of heart failure was higher than of other echocardiographic parameters. The area under the ROC curve (AUC) for the reservoir strain was 0.922 (95 % confidence interval, CI, 0.851–0.967), which was significantly greater than for Е / е’: 0.713 (0.613–0.800); the LAVI was 0.724 (0.624–0.809); and the PASP was 0.764 (0.668–0.844). A LAS value in the reservoir phase less than 22 % predicts a positive result of DST with a probability of 88.9 % (76.5–95.2 %). Higher values of the strain allow expecting a negative DST result with a probability of 88.7 % (77.4–94.7 %).Conclusion If the DST cannot be performed for a noninvasive diagnosis of heart failure with preserved ejection fraction, a positive result of this test can be predicted by a decrease of LAS in the reservoir phase to 21 % or lower. The diagnostic accuracy of this criterion is 88.8 % (81.0–93.6 %).
Correlation of stature with arm span along with its significance in north Indian adult population
Authors: Kumar Sumit , Agrawal Vasudha , Singh Pradeep , Bhardwaj Kamal 
Published: October 2022

: Stature is the qualitative and quantitative measurement of a personality. The purpose of this present study is to estimate the correlation of stature with arm span and to derive regression formulae for calculating the stature from arm span in adult males and Females of North Indian population. This research was done on 400 adult human subjects, (200 males and 200 Methods: females) of North Indian Population. The total number of subjects were categorised into four groups according to the age: Category 1 - 23 - 26 years of age, Category 2 – 27- 30 years of age, Category 3 – 31-34 years of age, Category 4 – 35-39 years of age. Stature and arm span were measured and mean value, standard deviation and Pearson's correlation coeffcient was calculated. Correlation between parameters with age group and gender has been estimated. : Correlation of Stature and arm Span is 0.66 in males, 0.65 in females and p value is&#60;0.001. The results of the study found that stature and arm span shows statistically signifcant positive correlation. : Stature shows a statistically significant positive correlation with arm span in adult males and females. Thus, for reconstruction surgeries of limb, it is a critical anthropologic tool. It can also be applicable in identifying an individual in mass disasters where the case is deteriorated, damaged and disfigured.
Preadmission profile and academic performance: Are we selecting the best students for medicine?
Authors: Athavale Sunita Arvind , Kotgirwar Sheetal , Lalwani Rekha 
Published: October 2022

India has the largest number of medical colleges in the world. Selection process for entry in these colleges is through entrance examination only. The present study was an attempt to explore such factors in pre admission profile of students that can predict the academic performance of the students. This observational cross-sectional study was carried out on 149 students who appeared for the university examination for first year MBBS of tertiary care teaching and research medical institute of Government of India, Bhopal. A prevalidated, pretested, structured questionnaire was used to collect information from the students regarding their sociodemographic and academic profile. Relationship between the study parameters and academic performance of students was explored statiscally.Majority of the study participants belonged to english medium, urban private schools. Almost 85% hailed from higher socioeconomic strata. Study parameters like performance of students in class X and XII, were positively statistically significantly correlated, while number of attempts taken to clear the entrance was negatively correlated to academic performance. Parameters like socioeconomic status, language, proficiency, place of stay and type of school did not show any relation with the academic performance. The entrance examination was found to be skewed towards students from one particular school board, urban, english medium students from higher socioeconomic strata. Possibility of adding scores of class XII and limiting the number of attempts in entrance examination needs to be considered. A level playing field needs to be provided for students across all school boards and across all the socioeconomic, linguistic and geographic backgrounds.
Scale for the evaluation of visitor experiences in a shopping center in Cali, Colombia
Authors: Alvarez-Cano Ana Milena , José Luis Ronquillo Horsten  
Published: October 2022

This article presents the reliability and validity of a scale that evaluates the experiences of visitors to the shopping center in Cali - Colombia. The methodology is framed within a quantitative, descriptive, and causal approach, through the application of the hypothetical-deductive method. The variables considered in the measurement scale were determined from a theoretical review and content validation. To collect the information, a personal survey was administered to a sample of 343 customers. The validity and reliability of the scale was determined by Exploratory Factor Analysis, Cronbach's coefficient, and Confirmatory Factor Analysis. Among the main findings, it is highlighted that the scale shows high reliability and internal consistency since one factor explains 50% of the total accumulated variance and the total Cronbach's Alpha is 0.846. When the confirmatory model was applied, positive correlations were identified between the indicators and the variables and between the three variables. Therefore, the final scale consisted of three: subscales emotional experiences, sensory experiences, cognitive experiences, and 23 items.