bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Genetic Information on Neonatologists’ Decisions: A Psychological Experiment
Authors: Callahan Katharine Press , Flibotte John , Skraban Cara , Wild Katherine Taylor , Joffe Steven , Munson David , Feudtner Chris 
Published: February 2022

BACKGROUND AND OBJECTIVESGenetic testing is expanding among ill neonates, yet the influence of genetic results on medical decision-making is not clear. With this study, we sought to determine how different types of genetic information with uncertain implications for prognosis influence clinicians’ decisions to recommend intensive versus palliative care.METHODSWe conducted a national study of neonatologists using a split sample experimental design. The questionnaire contained 4 clinical vignettes. Participants were randomly assigned to see one of 2 versions that varied only regarding whether they included the following genetic findings: (1) a variant of uncertain significance; (2) a genetic diagnosis that affects neurodevelopment but not acute survival; (3) a genetic versus nongenetic etiology of equally severe pathology; (4) a pending genetic testing result. Physicians answered questions about recommendations they would make for the patient described in each vignette.RESULTSVignette versions that included a variant of uncertain significance, a diagnosis foreshadowing neurodevelopmental impairment, or a genetic etiology of disease were all associated with an increased likelihood of recommending palliative rather than intensive care. A pending genetic test result did not have a significant effect on care recommendations.CONCLUSIONSFindings from this study of hypothetical cases suggest neonatologists apply uncertain genetic findings or those that herald neurodevelopmental disability in problematic ways. As genetic testing expands, understanding how it is used in decision-making and educating clinicians regarding appropriate use are paramount.
A new simple liquid chromatographic assay for gentamicin in presence of methylparaben and propylparaben
Authors: Ivković Branka , Milutinović Ivana , Čudina Olivera , Marković Bojan 
Published: February 2022

AbstractGentamicin sulfate is a potent broad spectrum aminoglycoside antibiotic which is used against Gram-positive and Gram-negative bacteria. A simple, isocratic HPLC method for separation, identification and determination of gentamicin and parabens (methylparaben and propylparaben) was developed and validated. To our knowledge there is no report about simultaneous determination of those three analytes in pharmaceutical products. The optimum chromatographic conditions were achieved on CN column with a mobile phase consisting of 0.15% triethylamine in 10 mM KH2PO4 aqueous solution (final pH 3.0 adjusted with H3PO4) and methanol in the ratio 70:30 (v/v), providing selective quantification of analytes within 5 min. The method was successfully validated according to ICH guidelines acceptance criteria in terms of selectivity, linearity, accuracy, precision and robustness. The linearity of the method was proved in defined concentrations ranges for gentamicin (0.32–1.04 mg mL−1), methylparaben (0.0072–0.0234 mg mL−1) and propylparaben (0.0008–0.0026 mg mL−1). Relative standard deviations calculated for all analytes in precision testing were <2% (analysis repeatability) and <3% (intermediate precision). Recovery values were between 98.87% and 101.67%. Chromatographic parameters are not significantly influenced by small variations of column temperature, pH and molarity of KH2PO4. Finally, the method was successfully applied for quantitative determination of gentamicin and parabens in commercially available solution for injection. Proposed HPLC method is found to be promising in terms of simplicity, analysis times and non-use of derivatization and ion-pair agents.
Influenza elleni védőoltás: mi szól mellette és ellene?
Authors: Eörsi Dániel , Gács Zsófia , Kun Eszter 
Published: February 2022

Összefoglaló.
Bevezetés: A magyar felnőtt lakosság heterogén attitűdje
folytán az influenza elleni átoltottság elmarad az nemzetközi ajánlásoktól. A
háziorvosok meggyőző potenciálja jelentős, ezért fontos szerepük van a felnőtt
lakosság oltással kapcsolatos döntéseinek befolyásolásában.
Célkitűzés: Az influenza elleni oltásra vonatkozó támogató
és akadályozó tényezők azonosítása felnőtt háziorvosok és a teljes lakosság és
körében. Módszer: 1000 fő, a teljes felnőtt lakosságra
reprezentatív alany, valamint 317 fő, felnőtt- és vegyes praxisban dolgozó
háziorvosokra reprezentatív orvos megkérdezése önkitöltős online kérdőív
segítségével. Eredmények: Az influenza elleni oltás lehetősége
93%-ban ismert a lakosság számára, 30% a leginkább a háziorvos tanácsát követné
ebben a kérdésben. A háziorvosok jelentősen túlbecsülik az ellátott lakosság
átoltottságát. Az oltást nem tervezők leggyakoribb indokai: nem tartják
veszélyesnek az influenzát, bíznak a saját immunrendszerükben, tartanak az oltás
mellékhatásaitól. Megbeszélés: Elenyésző az influenza elleni
oltás lehetőségét mereven elutasítók aránya. A többség relatív indokok alapján
tartja kevésbé fontosnak ezt a lehetőséget. A háziorvos hiteles szereplő a
lakosság jelentős része számára. Következtetés: A háziorvos
szerepe kulcsfontosságú a lakosság átoltottságának növelésében. Orv Hetil. 2021;
163(6): 222–228.
Summary.
Introduction: Compared to the international guidelines, the flu
vaccination rate of the Hungarian adult population is not satisfactory due to
its heterogeneous attitude towards vaccination. Based on previous results, the
convincing potential of general practitioners seems to be significant, therefore
they have an important role when influencing people’s decision-making concerning
this topic. Objective: To identify drivers and barriers to flu
vaccination among general practitioners and the whole population.
Method: Adult subjects representing the whole general
population (n = 1000), and a representative sample of general practitioners (n =
317) surveyed through online self-completed questionnaires.
Results: 93% of the adult population is aware of influenza
vaccine’s existence. 30% prefer to follow the general practitioner’s advice on
this topic. General practitioners significantly over-estimate the vaccination
coverage of the population they serve. The most common reasons for not getting
vaccinated against flu: not considering the influenza dangerous, trusting their
own immune system, and being afraid of the side effects of the vaccine.
Conclusion: The rate of hard refusal of influenza
vaccination is negligible. The vast majority of the population consider this
option less important for relative reasons. The general practitioner is an
authentic actor for a large part of the population. Orv Hetil. 2022; 163(6):
222–228.
Driving Zn-MnO2 grid-scale batteries: A roadmap to cost-effective energy storage
Authors: Spoerke Erik D. , Passell Howard , Cowles Gabriel , Lambert Timothy N. , Yadav Gautam G. , Huang Jinchao , Banerjee Sanjoy , Chalamala Babu 
Published: February 2022

Highlights
Zn-MnO2 batteries promise safe, reliable energy storage, and this roadmap outlines a combination of manufacturing strategies and technical innovations that could make this goal achievable. Approaches such as improved efficiency of manufacturing and increasing active material utilization will be important to getting costs as low as $100/kWh, but key materials innovations that facilitate the full 2-electron capacity utilization of MnO2, the use of high energy density 3D electrodes, and the promise of a separator-free battery with greater than 2V potential offer a route to batteries at $50/kWh or less.

Abstract
Large-scale energy storage is certain to play a significant, enabling role in the evolution of the emerging electrical grid. Battery-based storage, while not a dominant form of storage today, has opportunity to expand its utility through safe, reliable, and cost-effective technologies. Here, secondary Zn–MnO2 batteries are highlighted as a promising extension of ubiquitous primary alkaline batteries, offering a safe, environmentally friendly chemistry in a scalable and practical energy dense technology. Importantly, there is a very realistic pathway to also making such batteries cost-effective at price points of $50/kWh or lower. By examining manufacturing examples at the Zn–MnO2 battery manufacturer Urban Electric Power, a roadmap has been created to realize such low-cost systems. By focusing on manufacturing optimization through reduced materials waste, scalable manufacturing, and effective materials selection, costs can be significantly reduced. Ultimately, though, coupling these approaches with emerging research and development advances to enable full capacity active materials utilization and battery voltages greater than 2V are likely needed to drive costs below a target of $50/kWh. Reaching this commercially important goal, especially with a chemistry that is safe, well-known, and reliably effective stands to inject Zn–MnO2 batteries in the storage landscape at a critical time in energy storage development and deployment.

Graphical abstract
ANDROID SOFTWARE AGING AND REJUVENATION MODEL CONSIDERING THE BATTERY CHARGE
Authors: Yakovyna V. S. , Uhrynovskyi B. V. 
Published: February 2022

Context. A feature of mobile systems is their dependence on battery charge, which is an important factor when planning various processes, in particular when planning time of performing software rejuvenation procedure.
Objective. The goal of this article is to develop a model of software aging process with performing rejuvenation procedure for the Android operating system considering the factor of battery charge.
Method. A complex model based on Continuous-Time Markov Chains is proposed, which combines the software aging and rejuvenation model, the user behavior model and consider battery charge factor. A graph of states and transitions describing a complex model is constructed. Based on the formed graph the system of differential equations is written. The system was calculated using the 4th order Runge-Kutta method. The optimal time for the rejuvenation procedure can be determined when rejuvenation will not interfere with the user and will be performed before the battery is fully discharged, ie when the probability of the system being in these states is the lowest.
Results. The simulation of the developed model for test values of transition rates is performed. Considering the battery charge model allows to avoid planning the rejuvenation procedure at a time when the mobile device is likely to have a low charge or be completely discharged.
Conclusions. The proposed model based on the Markov chain allows to predict the start time of software rejuvenation procedure, considering both user behavior and battery level, which can have a significant impact on the predicted time. Also, the early implementation of the rejuvenation procedure may have the effect of reducing the system workload and delaying the discharge of the device, which should be checked in further studies. The expediency and importance of the consideration of battery charge factor and the need for further study of the proposed software aging and rejuvenation model are substantiated.
First record of Cymatodiscus planetophorus (Bacillariophyta) for littorals of NW Mexico; ecological remarks
Authors: Estrada Gutiérrez K. M. , Hernández Almeida O. U. , Siqueiros Beltrones D. A. , Flores Ortega J. R. 
Published: February 2022

AbstractAs part of a floristic analysis of diatoms (Bacillariophyta) at Reserva de la Biosfera Marismas Nacionales in Nayarit, Mexico, Cymatodiscus planetophorus is recorded for the first time in the northwestern coasts of Mexico. Samples were collected from various substrata in wetlands with an estuarine flux in areas of production and fishing of pleasure oyster Crassostrea corteziensis and mullet Mugil curema, respectively. Specimens of C. planetophorus were successfully distinguished from Cymatotheca weissflogii on the basis of meristic and morphological characteristics using optic microscopy. Their frequency and abundance on the inspected substrata confirm the benthic/tychoplanktic habit of this taxon. Both M. curema and C. corteziensis are added to the list of consumers of C. planetophorus; the latter also as new substrate. Complementary ecological remarks are provided. ResumenCymatodiscus planetophorus (Bacillariophyta) se registra por primera vez en las costas del Noroeste de México, como parte de un análisis florístico de diatomeas de la Reserva de la Biosfera Marismas Nacionales en Nayarit, México. Se recolectaron muestras de varios sustratos en humedales con flujo estuarino en áreas de producción y pesca de ostión de placer Crassostrea corteziensis y liza Mugil curema, respectivamente. Especímenes de C. planetophorus fueron identificados con base en sus características merísticas y morfológicas mediante microscopía óptica, discriminándolos morfológicamente de Cymatotheca weissflogii. Según su frecuencia en los sustratos examinados se confirma el hábito bentónico/ticoplanctónico de este taxón. Mugil curema y C. corteziensis se agregan a la lista de consumidores de C. planetophorus; este último como nuevo sustrato. Asimismo, se proporcionan observaciones ecológicas complementarias.
EFFECT OF BACILLUS CEREUS ON DEVELOPMENT OF MIGRATORY LOCUST, LOCUSTA MIGRATORIA (R&F)
Authors: Raut V.D. , M.M. Rai M. Sen  and 
Published: February 2022

Migratory locust, Locusta migratoria (Acrididae: Orthoptera) is a serious oligophagous pest of agriculture, found mostly in African, Asian and Australian continents. A bacterium isolated from eggs of L. migratoria was identified as Bacillus cereus CSBRLE2. The pathogenic effects of B. cereus on development and various tissues and haemolymph protein in L. migratoria have been investigated. Third instar nymphs were starved and inoculated with 10 ìl of bacterial suspension having concentration of 8x108 cfu/ml. The individuals were maintained in the laboratory up to adult maturation and egg laying. Body weight of the B. cereus inoculated individuals significantly reduced as compared to control. High mortality and lower fecundity and hatching percentage observed in the groups inoculated with bacterium. Inoculation of bacteria reduced the total haemolymph protein in adults as compared to control. The present study demonstrates that B. cereus could be used against L. migratoria in combination with other viable agents to help in management of locust and grasshoppers population in the field.
FOOD CONSUMPTION AND NUTRITIONAL INDICES OF OAK TASAR WORM ANTHERAEA PROYLEI (JOLLY) FED ON QUERCUS GLAUCA
Authors: B. R. Kaushal G. Pathak, H. Pande Lohani, J. Siddhu, , Palliwal S. 
Published: February 2022

Studies were conducted under laboratory conditions to evaluate the food consumption and nutritional indices for the development of Antheraea proylei larvae fed on Quercus glauca. Larval duration was 5.4±0.489, 6.4±0.48, 7.2±0.4, 9.8±0.74 and 14.2±0.74 days in the 1st, 2nd, 3rd, 4th and 5th instars, respectively. Larvae consumed a total of 28.85 g insect– ¹ day– ¹, egested 4.164 g insect– ¹ day– ¹ and assimilated 24.69 g insect– ¹ day– ¹ of food provided. 82.3% of tissue growth was observed in the 4th and 5th instar larvae. Approximate digestibility (AD) decreased from 91.94% in the first instar larva to 80.79% in the 5th instar larva. Efficiency of conversion of digested food (ECD) into body tissue and efficiency of conversion of ingested food into growth (ECI) increased from 1st instar larva to 5th instar larva. The result obtained in the present study indicate that Q. glauca could serve as an alternate host plant for rearing A. proylei in areas where the main host plant Q. serrata is not found.
Consistency of Non-Double-Couple Components of Seismic Moment Tensors with Earthquake Magnitude and Mechanism
Authors: Rösler Boris , Stein Seth 
Published: February 2022

Abstract
Earthquake moment tensors can be decomposed into double-couple components describing slip on planar faults and non-double-couple (NDC) components. NDC components can arise in three ways. Some appear to be intrinsic, indicating complex source processes differing from slip on a fault for earthquakes in specific geologic environments, notably volcanic areas. Others are additive, reflecting the combined effect of double-couple sources on multiple faults with different geometries. Alternatively, they may be artifactual, results of the inversion without geologic meaning. Combining moment tensors from three global and four regional catalogs for 2016–2020 provides a dataset of NDC components of 12,856 earthquakes with 2.9&lt;Mw&lt;8.2 in various geologic environments. The distributions of NDC components vary only slightly with magnitude, with a mean deviation from a double-couple source of around 20%. The consistency suggests that most NDC components do not reflect rupture on multiple faults, which is expected only for larger earthquakes. Similarly, there are only small differences in NDC components between earthquakes with different faulting mechanisms or in different geologic environments. These consistencies suggest that most NDC components are not intrinsic due to complex source processes that are often assumed to be most likely in volcanic and thus extensional areas. Hence, it appears that for most earthquakes, especially smaller ones, the NDC components are largely artifacts of the inversion.
Ambient Vibration Modal Analysis of Natural Rock Towers and Fins
Authors: Finnegan Riley , Moore Jeffrey R. , Geimer Paul R. , Dzubay Alex , Bessette-Kirton Erin K. , Bodtker Jackson , Vollinger Kathryn 
Published: February 2022

Abstract
The dynamic properties of freestanding rock towers are important inputs for seismic stability and vibration hazard assessments, however data describing the natural frequencies, mode shapes, and damping ratios of these landforms remain rare. We measured the ambient vibration of 14 sandstone and conglomerate rock towers and fins in Utah, United States, using broadband seismometers and nodal geophones. Fundamental frequencies vary between 0.8 and 15 Hz—inversely with tower height—and generally exhibit subhorizontal modal vectors oriented parallel to the minimum tower width. Modal damping ratios are low across all features, between 0.6% and 2.2%. We reproduced measured modal attributes in 3D numerical eigenfrequency models for 10 of the 14 landforms, showing that the fundamental mode of these features is full-height bending akin to a cantilever. Fin-like landforms commonly have a torsional second mode whereas tower-like features have a second full-height bending mode subperpendicular to the fundamental. In line with beam theory predictions, our data confirm that fundamental frequencies scale with the ratio of a tower’s width to its squared height. Compiled data from 18 other sites support our results, and taken together, provide guidance for estimating the modal properties of rock towers required for vibration risk assessment and paleoseismic shaking intensity analysis in different settings.
Perbedaan Kecepatan Gerak dan Daya Ledak Otot Lengan antara Peserta Kegiatan Ekstrakurikuler Bolabasket Sekolah Menengah Atas
Authors: Armanzah Maulana , Nurrochmah Siti 
Published: February 2022

The purpose of this study was to determine differences in movement speed and explosive power of arm muscles between participants in the extracurricular activities of SMAN 1 Lawang and SMAN 1 Singosari Malang Regency. This study uses liliefors test techniques, homogeneity, and free sample t test. Based on the results of the study it can be concluded that there are differences in the speed of movement and explosive power of the arm muscles between the participants of the extracurricular activities of the Lawang SMAN basketball and SMAN 1 Singosari Malang Regency. This can be caused by several factors: (1) lack of frequency of practice, (2) physical exercise is rarely given (3) exercise is only extracurricular time.
: Tujuan penelitian untuk mengetahui perbedaan kecepatan gerak dan daya ledak otot lengan antara peserta kegiatan ekstrakurikuler bolabasket SMAN 1 Lawang dan SMAN 1 Singosari Kabupaten Malang. Penelitian ini menggunakan teknik uji liliefors, homogenitas, dan uji t sampel bebas. Berdasarkan hasil penelitian dapat disimpulkan bahwa terdapat perbedaan kecepatan gerak dan daya ledak otot lengan antara peserta kegiatan ekstrakurikuler bolabasket SMAN Lawang dan SMAN 1 Singosari Kabupaten Malang. Hal ini dapat disebabkan oleh beberapa faktor: (1) kurangnya frekuensi berlatih, (2) jarang diberi latihan fisik (3) latihan hanya waktu ekstrakurikuler.
Pertumbuhan dan Perkembangan Motorik Kasar Pada Kelas Rendah Sekolah Dasar
Authors: Fadhullah Rizki , Wiguno Lokananta 
Published: February 2022

Based on the results obtained by interviews, data collection was carried out to determine growth through anthropometric tests and motor development through TGMD-2 because there was no research data on looking at gross motor growth and development. The purpose of this study was to describe the gross motor development and growth of children aged 7-9 years. This research is descriptive quantitative type. The techniques used are stratified and purposive sampling. The sample used was 7 to 9 years of age. Based on the exposure to the data above, it can be concluded that the anthropometric measurements of students aged 7-9 years have an average result for each age, the tests for gross motor skills of students aged 7-9 years are mostly good.
Berdasarkan hasil yang diperoleh wawancara bahwa pengambilan data dilakukan untuk mengetahui pertumbuhan melalui tes antropometri dan perkembangan motorik melalui TGMD-2 karena belum ada data penelitian tentang melihat pertumbuhan dan perkembangan motorik kasar. Tujuan penelitian ini adalah menggambarkan pertumbuhan dan perkembangan motorik kasar anak usia 7-9 tahun. Penelitian ini jenis deskriptif kuantitatif. Teknik yang digunakan yaitu stratified dan purposive sampling. Sampel yang digunakan usia 7 sampai 9 tahun. Berdasarkan paparan data diatas dapat disimpulkan bahwa pengukuran antropometri peserta didik usia 7-9 tahun terdapat hasil rata-rata pada setiap usia, tes untuk motorik kasar peserta didik usia 7-9 tahun sebagian besar menunjukkan baik.