bluuebunny/crossref_metadata_2025_split huggingface dataset:
Profil Kesalahan Konseptual dan Prosedural Mahasiswa STKIP Paris Barantai dalam Menyelesaikan Soal Geometri Analitik Datar
Authors: Hartini Hartini 
Published: March 2022

The purpose of this study is to describe (1) conceptual and procedural errors in solving mathematical problems related to parabola and hyperbole in STKIP Paris Barantai Kotabaru semester III students in the 2019/2010 school year; (2) the causes of conceptual and procedural errors in solving mathematical problems related to parabola and hyperbole in the third semester students of STKIP Paris Barantai Kotabaru in the academic year 2019/2010. This research is categorized into qualitative research with a descriptive-explorative approach. Data collection techniques through the provision of diagnostic tests and through interviews. The research subjects consisted of 6 (six) people, who were divided into 3 (three) categories namely, 2 (two) low-ability students, 2 (two) medium-ability students, and 2 (two) high-ability students. The results showed that: 1) Conceptual errors that occur in low category subjects were wrong in the agreed concept, and were not quite right in using the formula or theorem in solving a problem; 2) Procedural errors occur in middle category subjects and low category subjects; 3) Concept and procedural errors (occur) occur in low category subjects, namely a) errors using formulas, b) irregularities in the steps to solve problems, and c) student errors in observing and looking for clues.

Keywords: Profile, Procedural Error, Conceptual Error, Flat Alitic Geometry.
MENINGKATKAN KETERAMPILAN MEMBACA PEMAHAMAN MELALUI METODE SQ3R SISWA KELAS V SDN 2 RAMPA KECAMATAN PULAU LAUT UTARA KABUPATEN KOTABARU
Authors: Munaji Munaji 
Published: March 2022

Tujuan penelitian ini adalah (1) Mengetahui penggunaan metode SQ3R dapat meningkatkan hasil belajar siswa kelas V SDN 2 Rampa dalam membaca pemahaman (2) Mengetahui aktifitas siswa terhadap pembelajaran dengan menggunakan metode SQ3R dalam pembelajaran keterampilan membaca pemahaman (3) Mengetahui aktifitas guru terhadap pembelajaran dengan menggunakan metode SQ3R dalam pembelajaran keterampilan membaca pemahaman. Metode yang digunakan dalam penelitian ini adalah metode penelitian kualitatif yang bersifat deskriptif yaitu menggambarkan secara obyektif dan aktual tahapan pembelajaran. Sedangkan jenis penelitian ini adalah tindakan kelas yaitu bentuk pembelajaran yang bersifat reflektif untuk memperbaiki kondisi pembelajaran dan meningkatkan keterampilan membaca pemahaman dengan metode SQ3R. Jenis penelitian kualitatif dengan menganalisa data secara kuantitatif melalui langkah-langkah pengumpulan, pengolahan, penganalisaan dan penyajian data dengan teknik observasi dan tes kemampuan siswa membaca pemahaman pada proses pembelajaran. Hasil penelitian menunjukkan bahwa penerapan metode SQ3R dapat meningkatkan keterampilan siswa dalam membaca pemahaman dan mengubah perilaku siswa ke arah yang positif. Hal ini diketahui dari nilai hasil belajar yang secara bertahap meningkat mencapai indikator ketuntasan belajar dan dibuktikan dari nilai tes hasil belajar siswa dari nilai rata-rata 70,4 dengan ketuntasan klasikal 80% meningkat menjadi 83,2 dengan ketuntasan klasikal 92%.

Kata Kunci: Membaca, Metode SQ3R.
Peran Orangtua Dan Guru Pendidikan Agama Kristen Dalam Pembentukan Karakter Rohani Siswa Di SMP Negeri 2 Taman Sidoarjo Jawa Timur
Authors: Simanjutak Adianto 
Published: March 2022

The study aims to describe the role of Christian education parents and teachers in the formation of children's spiritual characters. The focus of this research is how Christian education parent and teacher roles are in the formation of child's spiritual character. Research was conducted at Junior high school Negeri 2 Taman Kabupaten Sidoarjo and as a source of data for children's parents, teacher Christian education and a Christian child. Data collection techniques consist of literature reviews, interviews, and documentation. The instruments in this research are interview guidelines, and are denomented. The data analysis technique used in this study is a qualitative data analysis, following the concepts given Miles and Huberman and Spradley. From the results of the analysis of data obtained the conclusion of the parent role in the formation of children's spiritual character in the school Junior high school Negeri 2 Taman Kabupaten Sidoarjo, not entirely fulfilled. While the role of teachers Christian education Junior high school Negeri 2 Taman Kabupaten Sidoarjo, has been done with the maximum, namely as educators, counselors, advisers, motivators, evangelists, communicators, and socialization agents and roles in accordance with the demands of the curriculum K13.
Abstrak Indonesia
Penelitian ini bertujuan untuk mendeskripsikan peran orang tua dan guru PAK dalam pembentukan karakter spiritual Siswa. Fokus penelitian ini adalah bagaimana peran orang tua dan guru PAK dalam pembentukan karakter spiritual Siswa. Penelitian dilakukan di SMP Negeri 2 Taman Kabupaten Sidoarjo dan sebagai sumber data bagi orang tua Siswa, Guru PAK, dan Siswa Kristen. Teknik pengumpulan data terdiri dari studi pustaka, wawancara, dan dokumentasi. Instrumen dalam penelitian ini adalah pedoman wawancara, dan dekumentasi. Teknik analisis data yang digunakan dalam penelitian ini adalah analisis data kualitatif, mengikuti konsep yang diberikan Miles dan Huberman dan Spradley. Dari hasil analisis data diperoleh kesimpulan peran orang tua dalam pembentukan karakter spiritual Siswa di sekolah SMP Negeri 2 Taman Kabupaten Sidoarjo , belum sepenuhnya terpenuhi. Sedangkan peran guru PAK SMP Negeri 2 Taman Sidoarjo , telah dilakukan dengan maksimal yaitu sebagai pendidik, konselor, pembimbing, motivator, penginjil, komunikator, dan agen sosialisasi dan peran sesuai dengan tuntutan kurikulum K13.
Artificially Increasing Cortical Tension Improves Mouse Oocytes Development by Attenuating Meiotic Defects During Vitrification
Authors: Du Xingzhu , Li Jun , Zhuan Qingrui , Zhang Luyao , Meng Lin , Ren Panyu , Huang Xiaohan , Bai Jiachen , Wan Pengcheng , Sun Wenquan , Hou Yunpeng , Zhu Shien , Fu Xiangwei 
Published: March 2022

Oocyte cryopreservation demonstrates great benefits in the conservation of animal germplasm resources and assisted reproductive technology. However, vitrification causes damages in oocytes, which would lead to the decrease of oocyte quality, and embryonic development post fertilization. Cytoskeleton plays an important role in regulating cell shape, organelle migration, cell division and mechanical signal transduction. Cortical tension is a reflection of the physiological state and contractile ability of cortical cytoskeleton. Appropriate cortical tension is prerequesite for normal oocyte meiosis. In the present study, oocyte cortical tension was examined by evaluating the levels of cortical tension-related protein pERM (Phospho-Ezrin/Radixin/Moesin) and pMRLC (Phospho-Myosin Light Chain 2). We found that the cortical tension of vitrified oocytes was decreased. Increasing cortical tension of vitrified oocytes by adding 10 μg/ml ConA during in vitro culture could significantly improve the polar body extrusion rate and embryo development. Furthermore, increasing the cortical tension could improve spindle positioning, maintain kinetochore-microtubule (KT-MT) attachment, strengthen spindle assembly checkpoint (SAC) activity, and reduce the aneuploidy rate in vitrified oocytes. In conclusion, vitrification induced a remarkable decrease in cortical tension, and increasing the cortical tension could rescue the meiosis defect and improve oocyte quality.
Triazine-Based Conjugated Microporous Polymers With Different Linkage Units for Visible Light–Driven Hydrogen Evolution
Authors: Sheng Qiannan , Zhong Xiujuan , Shang Qianqian , Dong YunYun , Zhao Jinsheng , Du Yuchang , Xie Yu 
Published: March 2022

Conjugated microporous polymers (CMPs), as a kind of two-dimensional material, have attracted extensive attention due to their advantages in visible light–driven photocatalytic splitting of water for hydrogen evolution. However, improving the microstructure and electronic structure of the material to enhance their photocatalytic performance for hydrogen evolution remains a challenge. We designed and reported two analogous CMPs including CMP-1 and CMP-2 that contain triazine and dibenzothiophene-S,S-dioxide units, which were prepared by Pd-catalyzed Suzuki-Miyaura coupling reaction. The main difference of two CMPs is that the triazine units are connected to benzene unit (CMP-1) or thiophene unit (CMP-2). Both of the CMPs exhibit excellent light capture capability, and compared with CMP-2, CMP-1 has faster separation rates and lower recombination rates for the charge carriers (electron/hole), and then, a higher hydrogen evolution rate was obtained from water decomposition reaction. We find the H2 production rate of CMP-1 can be up to 9,698.53 μmol g−1h −1, which is about twice of that of CMP-2. This work suggests that molecular design is a potent method to optimize the photocatalytic performance toward hydrogen evolution of the CMPs.
Silicon Passivation by Ultrathin Hafnium Oxide Layer for Photoelectrochemical Applications
Authors: Staišiūnas Laurynas , Kalinauskas Putinas , Juzeliūnas Eimutis , Grigucevičienė Asta , Leinartas Konstantinas , Niaura Gediminas , Stanionytė Sandra , Selskis Algirdas 
Published: March 2022

Hafnium oxide (HfO2) films on silicon have the potential for application in photovoltaic devices. However, very little is known about the photoelectrochemical and protective properties of HfO2 films on Si. In this study, ultrathin films of HfO2 in the range of 15–70 nm were deposited on p-Si and Au substrates by atomic layer deposition (ALD). Grazing incidence X-ray diffraction (GI-XRD) identified the amorphous structure of the layers. Quartz crystal nanogravimetry (QCN) with Si and Au substrates indicated dynamics of electrolyte intake into the oxide film. No indications of oxide dissolution have been observed in acid (pH 3) and alkaline (pH 12) electrolytes. Mott–Schottky plots showed that the dark Si surface adjacent to the SiHfO2 interface is positively charged in an acid electrolyte and negatively charged in an alkaline electrolyte. The number of photoelectrons was determined to be much greater than the doping level of silicon. The cathodic photoactivity of the p-Si electrode protected by HfO2 films was studied with respect to the reaction of hydrogen reduction in acid and alkaline solutions. In acid solution, the film enhanced the reduction process when compared to that on the coating free electrode. The acceleration effect was explained in terms of prevention of silicon oxide formation, whose passivating capability is higher than that of hafnia films. In an alkaline electrolyte, an inhibition effect of the film was determined. Hafnia films protected Si from corrosion in this medium; however, at the same time, the film reduced electrode activity.
Quantitative Visual Detection of Mercury Ions With Ratiometric Fluorescent Test Paper Sensor
Authors: Fan Mimi , Pan Zhihui , Wang Chunjuan , Guo Yang , Sun Jingran , Liu Mingzhu , Peng Bo , Wu Jin , Fang Yanjun 
Published: March 2022

A novel ratiometric fluorescence probe based on nitrogen-doped blue carbon dots (NCDs) and red gold nanoclusters (Au NCs) for mercuric ion (Hg2+) has been prepared and characterized. A user friendly fluorescent test paper based sensor combined with smartphone was fabricated for rapid visual and quantitative detection. Hg2+ can specifically bind to Au+ on the surface of Au NCs, leading to the quench of red fluorescence while the fluorescence intensity of the NCDs with blue fluorescence remained unchanged as a internal standard signal. The implement of paper-based sensor address some common drawback in analytical process such as the detection time, analysis cost. In a further demonstration, a homemade detection device with smartphone was used to qualify the Hg2+. After adding different concentration of Hg2+, red, purple, and blue colors were obtained on the detection zones of the fluorescent test paper. The Android App Color Grab was used to identify the red, green and blue (RGB) values of fluorescent color. The rapid visual and quantitative detection of Hg2+ was accomplished with the detection limit of 2.7 nM for fluorescence, 25 nM for smartphone and 32 nM for paper strip. The developed multi-mode detection platform was successfully applied to the detection of mercury ions in water samples with acceptable recoveries. The NCDs and Au NCs probe facilitate the one-site environmental monitoring for Hg2+ with “naked-eye” and smartphone.
Network-Based Differences in the Vaginal and Bladder Microbial Communities Between Women With and Without Urgency Urinary Incontinence
Authors: Nardos Rahel , Leung Eric T. , Dahl Erin M. , Davin Sean , Asquith Mark , Gregory W. Thomas , Karstens Lisa 
Published: March 2022

BackgroundLittle is known about the relationship of proximal urogenital microbiomes in the bladder and the vagina and how this contributes to bladder health. In this study, we use a microbial ecology and network framework to understand the dynamics of interactions/co-occurrences of bacteria in the bladder and vagina in women with and without urgency urinary incontinence (UUI).MethodsWe collected vaginal swabs and catheterized urine specimens from 20 women with UUI (cases) and 30 women without UUI (controls). We sequenced the V4 region of the bacterial 16S rRNA gene and evaluated using alpha and beta diversity metrics. We used microbial network analysis to detect interactions in the microbiome and the betweenness centrality measure to identify central bacteria in the microbial network. Bacteria exhibiting maximum betweenness centrality are considered central to the microbe-wide networks and likely maintain the overall microbial network structure.ResultsThere were no significant differences in the vaginal or bladder microbiomes between cases and controls using alpha and beta diversity. Silhouette metric analysis identified two distinct microbiome clusters in both the bladder and vagina. One cluster was dominated by Lactobacillus genus while the other was more diverse. Network-based analyses demonstrated that vaginal and bladder microbial networks were different between cases and controls. In the vagina, there were similar numbers of genera and subgroup clusters in each network for cases and controls. However, cases tend to have more unique bacterial co-occurrences. While Bacteroides and Lactobacillus were the central bacteria with the highest betweenness centrality in controls, Aerococcus had the highest centrality in cases and correlated with bacteria commonly associated with bacterial vaginosis. In the bladder, cases have less than half as many network clusters compared to controls. Lactobacillus was the central bacteria in both groups but associated with several known uropathogens in cases. The number of shared bacterial genera between the bladder and the vagina differed between cases and controls, with cases having larger overlap (43%) compared to controls (29%).ConclusionOur study shows overlaps in microbial communities of bladder and vagina, with higher overlap in cases. We also identified differences in the bacteria that are central to the overall community structure.
Expansion of Intestinal Secretory Cell Population Induced by Listeria monocytogenes Infection: Accompanied With the Inhibition of NOTCH Pathway
Authors: Zhou Cong , Zhang Yuanyuan , Bassey Anthony , Huang Jie , Zou Yafang , Ye Keping 
Published: March 2022

Listeria monocytogenes, as a model organism, is a causative agent of enteric pathogen that causes systemic infection. However, the interaction of L. monocytogenes and small intestinal epithelium has not been fully elucidated yet. In this study, mice and intestinal organoids were chosen as the models to investigate the influence of L. monocytogenes infection on the intestinal secretory cells and its differentiation-related pathways. Results confirmed the phenomenon of intestinal damage that L. monocytogenes infection could lead to villi damage in mice, which was accompanied by the increase of TNF-α production in jejunum as well as lipopolysaccharide (LPS) secretion in serum. Moreover, it was demonstrated that L. monocytogenes infection increased the number of goblet and Paneth cells in mice and intestinal organoids and upregulated the expression of Muc2 and Lyz. Furthermore, L. monocytogenes decreased the relative expression of Notch pathway-related genes (Jag1, Dll4, Notch1, and Hes1) while upregulating the relative expression of Math1 gene in mice and intestinal organoids. This indicated that L. monocytogenes infection caused the inhibition of Notch pathway, which may be the reason for the increased number of goblet and Paneth cells in the intestine. Collectively, these results are expected to provide more information on the mechanism of L. monocytogenes infection in the intestine.
Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients
Authors: Ding Dafa , Yong Huijuan , You Na , Lu Wei , Yang Xu , Ye Xiaolong , Wang Yayun , Cai Tingting , Zheng Xiaoling , Chen Hui , Cui Bota , Zhang Faming , Liu Xingyin , Mao Jian-Hua , Lu Yibing , Chang Hang 
Published: March 2022

BackgroundIncreasing evidence shows that alterations in gut microbiome (GM) contribute to the development of type 2 diabetes mellitus (T2DM), and fecal microbiota transplantation (FMT) successfully treats various human diseases. However, the benefits of FMT therapy to T2DM patients remain unknown.MethodsWe enrolled 17 patients with T2DM for nonblinded, one-armed intervention trial of FMT. A total of 20 healthy individuals were recruited as the baseline control. HbA1c% and metabolic parameter change were evaluated in 17 T2DM patients 12 weeks after they received FMT from healthy donors. The GM composition was characterized by 16S rRNA gene amplicon sequencing from fecal samples prior to and 12 weeks after FMT treatment.ResultsWe found that the GM of T2DM patients was reconstituted by FMT. We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p&lt;0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p&lt;0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p&lt;0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p&lt;0.01) at 12 weeks after FMT. Closely evaluating the changes in these assays, we found individual variability in response to FMT treatment. Out of 17 T2DM patients, 11 were found to significantly improve T2DM symptoms. The FMT responders have significantly higher levels of the family Rikenellaceae and the genus Anaerotruncus (family Ruminococcaceae) in their pretreated fecal in comparison to nonresponders, which could predict the clinical response with an area under the curve of 0.83.ConclusionOur findings suggest that certain T2DM patients can potentially benefit from FMT, and the pretreated abundance of Rikenellaceae and Anaerotruncus in the fecal of patients may serve as potential biomarkers for selecting T2DM patients to receive FMT.
Bibliometric and Visual Analysis on Metabolomics in Coronary Artery Disease Research
Authors: Yu Ning , Wang Ruirui , Liu Baocheng , Zhang Lei 
Published: March 2022

BackgroundMetabolomics has immense research value in coronary artery disease and has drawn increasing attention over the past decades. Many articles have been published in this field, which may challenge researchers aiming to investigate all the available information. However, bibliometrics can provide deep insights into this research field.ObjectiveWe aimed to qualitatively and quantitatively study metabolomics and coronary artery disease research, visually analyse the development status, trends, research hotspots, and frontiers of this field, and provide a reference for research on coronary artery disease.MethodsArticles were acquired from the Web of Science Core Collection. VOSviewer and CiteSpace software were used to analyse publication growth, country/region, institution, journal distribution, author, reference, and keywords, and detected the keywords with strong citation burstness to identify emerging topics.ResultsA total of 1121 references were obtained, and the annual number of publications increased over the past 16 years. Metabolomics research has shown a gradual upward trend in coronary artery disease. The United States of America and China ranked at the top in terms of percentage of articles. The institution with the highest number of research publications in this field was Harvard University, followed by the University of California System and Brigham Women’s Hospital. The most frequently cited authors included Hazen SL, Tang WH, and Wang ZN. Ala-Korpela M was the most productive author, followed by Clish CB and Adamski J. The journal with the most publications in this field was Scientific Reports, followed by PLoS One and the Journal of Proteome Research. The keywords used at a high frequency were “risk,” “biomarkers,” “insulin resistance,” and “atherosclerosis.” Burst detection analysis of top keywords showed that “microbiota,” “tryptophan,” and “diabetes” are the current research frontiers in this field.ConclusionThis study provides useful information for acquiring knowledge on metabolomics and coronary artery diseases. Metabolomics research has shown a gradual upward trend in coronary artery disease studies over the past 16 years. Research on tryptophan metabolism regulated by intestinal flora will become an emerging academic trend in this field, which can offer guidance for more extensive and in-depth studies in the future.
Hypertensive Disorders in Pregnancy Are Associated With Congenital Heart Defects in Offspring: A Systematic Review and Meta-Analysis
Authors: Zhang Senmao , Qiu Xing , Wang Tingting , Chen Letao , Li Jinqi , Diao Jingyi , Li Yihuan , Qin Jiabi , Chen Lizhang , Jiang Yurong 
Published: March 2022

BackgroundAlthough research indicates an association between hypertensive disorders of pregnancy (HDP) and congenital heart defects (CHDs) in offspring, consistency is still lacking. Therefore, we aimed to synthesize the updated published epidemiologic evidence to estimate the association of maternal HDP with the risk of total CHDs and its phenotypes in offspring.MethodsA systematic search of Web of Science Database, PubMed, and Embase were searched from inception through April 30, 2021 based on a preprepared protocol, and the reference lists were also manually searched. The combined risk estimates were calculated using either the fixed-effect models or random-effect models. Possible heterogeneity moderators were detected by subgroup, sensitivity analyses, and Galbraith plot.ResultsTwenty-four studies involving 477,839 CHDs cases among 40,394,699 participants were included in our meta-analysis. Mothers who had HDP exposure were significantly associated with an increased risk of total CHDs compared with non-exposure. When maternal HDP exposure was further subdivided into pre-eclampsia (OR = 1.79, 95% CI: 1.50–2.13), gestational hypertension (OR = 1.16, 95% CI: 1.02–1.31), and chronic hypertension (OR = 1.68, 95% CI: 1.49–1.89), a significantly increased risk of total CHDs were still presented. Furthermore, a statistically significant increased association was found between maternal HDP exposure and most CHD phenotypes. Besides, relevant heterogeneity moderators have been identified by subgroup and sensitivity analyses.ConclusionOur study suggested that maternal HDP exposure may be associated with an increase in the risk of CHDs in offspring. These findings highlight the need for greater surveillance of pregnant women with HDP exposure to allow early prevention that may be good for reducing the risk of CHDs in offspring.Clinical Trial Registration[www.ClinicalTrials.gov], identifier [CRD42021268093].