bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sheep scab: comparison of spatial and temporal patterns determined by clinical diagnosis or ELISA
Authors: Makepeace Chloe , Nixon Emily Joanne , Burgess Stewart T. G. , Stubbings Lesley , Wall Richard 
Published: November 2022

AbstractBackgroundOvine psoroptic mange (sheep scab) is an infectious condition caused by an allergen-induced hypersensitivity response to the mitePsoroptes ovis. Infestation results in clinical disease, economic loss and welfare issues in many sheep-producing countries. The aim of this study was to compare the prevalence and spatial pattern of sheep scab on contiguous farms, using both self-reported clinical outbreak history (2012–2020) and serological testing with an enzyme-linked immunosorbent assay (2021/2022).MethodsFarms included in the study were located in three regions of known high scab prevalence in North, Central and Southwest England. In total, 254 farms completed both a questionnaire, which provided the clinical scab history of the farm, and submitted results of serological testing with the ELISA.ResultsA scab outbreak was reported by 17.4% (± confidence interval [CI]: 4.6%;n = 48) of farms in 2020 based on clinical diagnosis; scab was diagnosed by the ELISA on 25.6% (± 5.5%;n = 65) of farms in 2021/2022. Comparison of self-reported clinical scab cases with the ELISA test results identified a group of farms (n = 52) that did not report scab in 2020, or in some cases did not report having scab over the previous 8 years (n = 20), but whose flocks were nevertheless seropositive in 2021/2022.ConclusionA small number of flocks, particularly those using common grazings in North England, where handling is infrequent, often comprising less susceptible sheep breeds, may have persistent scab infestations that are generally undetected by clinical inspection. The data highlight the advantages of serological testing to identify exposure to scab in flocks where clinical signs are less easily detected.Graphical Abstract
Periostin overexpression in scleroderma cardiac tissue and its utility as a marker for disease complications
Authors: El-Adili Fatima , Lui Justin K. , Najem Mortada , Farina Giuseppina , Trojanowska Maria , Sam Flora , Bujor Andreea M. 
Published: November 2022

Abstract
Objective
To evaluate the levels of periostin in patients with systemic sclerosis (SSc) and their association with features of systemic sclerosis.

Methods
The levels of periostin were assessed in the serum of 106 SSc patients and 22 healthy controls and by immunofluorescence staining in cardiac tissue from 4 SSc patients and 4 controls. Serum periostin was measured via enzyme-linked immunosorbent assay. The results were analyzed using Mann-Whitney test or Kruskal-Wallis test followed by Dunn’s multiple comparisons tests and Spearman’s test for correlations. Cardiac tissue from SSc patients and controls was stained for periostin and co-stained for periostin and collagen type I using immunofluorescence.

Results
Periostin levels were higher in patients with SSc compared to controls and directly correlated to modified Rodnan skin score and echocardiography parameters of left ventricular measurements. Immunofluorescence staining in SSc cardiac tissue showed patchy periostin expression in all SSc patients, but not in controls. Furthermore, there was extensive periostin expression even in areas without collagen deposition, while all established fibrotic areas showed colocalization of collagen and periostin. There was no association between periostin levels and interstitial lung disease, pulmonary hypertension or other vascular complications.

Conclusion
Periostin is elevated in SSc cardiac tissue in vivo and circulating levels of periostin are increased in SSc, correlating with the extent of disease duration, degree of skin fibrosis, and left ventricular structural assessments. Periostin may be a potential biomarker that can provide further pathogenic insight into cardiac fibrosis in SSc.
Seizures, deep vein thrombosis, and pulmonary emboli in a severe case of May–Thurner syndrome: a case report
Authors: Seely Kevin D. , Arreola Heidi J. , Paul Loveleen K. , Higgs Jordan A. , Brooks Benjamin , Anderson Randal C. 
Published: November 2022

Abstract
Background
May–Thurner syndrome is a vascular disorder caused by the right common iliac artery compressing the left common iliac vein against the lumbar spine, causing distal venous stasis and potentially leading to fibrous change in the venous wall structure. Although May–Thurner syndrome is most commonly discovered in females upon investigation of new-onset deep vein thrombosis, we present the case of an otherwise healthy 29-year-old male with severe May–Thurner syndrome who presented with seizures, bilateral deep vein thrombosis, and diffuse pulmonary emboli. Seizures constituted the earliest presenting symptoms for the patient. Although it is difficult to prove that the patient’s seizures were related to the May–Thurner syndrome, this possible association renders this case extraordinary.

Case presentation
This report describes the case of a 29-year-old previously healthy white male with a severe case of left-sided May–Thurner syndrome that required extensive medical and interventional treatment. The patient experienced two seizures, one month apart, both of which occurred while residing at high altitude. The patient had no prior history of seizures, and epilepsy was ruled out. Three weeks after the second seizure, he presented to the emergency room with hemoptysis, dyspnea, and severe leg pain. Sites of thrombus were confirmed in both legs and diffusely in the lungs. Etiological work-up after treatment with intravenous tissue plasminogen activator revealed May–Thurner syndrome. Hematology workup including genetic testing showed no evidence of coagulopathy. Bilateral common iliac venous stents were placed to attempt definitive treatment. Despite stenting, the patient had another thrombotic event with associated sequelae after discontinuation of anticoagulation. The patient has not had another seizure since the stents were placed. Despite the negative testing, the patient remains on lifelong chemoprophylaxis in the event of an undiscovered hypercoagulopathy.

Conclusions
The care team theorizes that the seizures resulted from hypoxia due to May–Thurner syndrome-induced hemostasis and associated thrombotic events, the high-altitude location of his residence at the time he experienced the seizures, and shallow breathing during sleep. For patients with lower limb venous thrombosis, May–Thurner syndrome should be considered in the differential diagnosis. Endovascular treatment followed by extended prophylactic anticoagulation therapy until the patient is determined to be no longer at risk for thrombosis is recommended. Post-venoplasty thrombosis is a common complication of endovascular treatment of May–Thurner syndrome and should be carefully monitored.
Urbanization, economic development, and environmental changes in transitional economies in the global south: a case of Yangon
Authors: Fan Peilei , Chen Jiquan , Fung Cadi , Naing Zaw , Ouyang Zutao , Nyunt Khaing Moe , Myint Zin Nwe , Qi Jiaguo , Messina Joseph P. , Myint Soe W. , Peter Brad G. 
Published: November 2022

Abstract
Background
Transitional economies in Southeast Asia—a distinct group of developing countries—have experienced rapid urbanization in the past several decades due to the economic transition that fundamentally changed the function of their economies, societies and the environment. Myanmar, one of the least developed transitional economies in Southeast Asia, increased urbanization substantially from 25% in 1990 to 31% in 2019. However, major knowledge gaps exist in understanding the changes in urban land use and land cover and environment and their drivers in its cities.

Methods
We studied Yangon, the largest city in Myanmar, for the urbanization, environmental changes, and the underlying driving forces in a radically transitioned economy in the developing world. Based on satellite imagery and historic land use maps, we quantified the expansion of urban built-up land and constructed the land conversion matrix from 1990 through 2020. We also used three air pollutants to illustrate the changes in environmental conditions. We analyzed the coupled dynamics among urbanization, economic development, and environmental changes. Through conducting a workshop with 20 local experts, we further analyzed the influence of human systems and natural systems on Yangon’s urbanization and sustainability.

Results
The city of Yangon expanded urban built-up land rapidly from 1990 to 2000, slowed down from 2000 to 2010, but gained momentum again from 2010 to 2020, with most newly added urban built-up land appearing to be converted from farmland and green land in both 1990–2000 and 2010–2020. Furthermore, the air pollutant concentration of CO decreased, but that of NO2 and PM2.5 increased in recent years. A positive correlation exists between population and economic development and the concentration of PM2.5 is highly associated with population, the economy, and the number of vehicles. Finally, the expert panel also identified other potential drivers for urbanization, including the extreme climate event of Cyclone Nargis, capital relocation, and globalization.

Conclusions
Our research highlights the dramatic expansion of urban land and degradation of urban environment measured by air pollutants and interdependent changes between urbanization, economic development, and environmental changes.
Effect of external use of Qingluo San on clinical efficacy in patients with acute gouty arthritis
Authors: Shu Chun , Yang Fang , Zhu Fubing , Hua Dongping 
Published: November 2022

Abstract
Objective
The present study aimed to observe the clinical efficacy of the external use of Qingluo San combined with diclofenac sodium double-release enteric capsules in the treatment of acute gouty arthritis (dampness–heat accumulation syndrome).

Methods
A total of 58 acute gouty arthritis patients were divided into two groups using the random number table method. Diclofenac sodium double-release enteric capsules were orally administered in the control group. Based on the treatment in the control group, the external use of Qingluo San was given in the treatment group, with 7-day course of treatment. The changes in visual analog scale (VAS) scores, the tenderness, swelling, and mobility function of the joint, and the traditional Chinese medicine (TCM) syndrome scores before and after the treatment, at day 0, 1, 3, 5 and 7, were observed in both groups, together with the comparison of laboratory indicators (erythrocyte sedimentation rate, ESR; C-reactive protein, CRP; uric acid, UA).

Results
The total effective rate was 96.55% in the treatment group and 82.76% in the control group. After treatment, the VAS score, the tenderness, swelling and function scores of the joint, and the TCM syndrome scores decreased in both groups. The treatment group was superior in improving the VAS scores, the tenderness, swelling and mobility function of the joint, and TCM syndrome scores, when compared to the control group (p < 0.05). The laboratory indicators, which included the ESR, CRP and UA, obviously decreased in both groups after treatment (p < 0.05). The ESR significantly decreased in the treatment group, when compared to the control group (p < 0.05).

Conclusion
The combination of the external use of Qingluo San and oral administration of diclofenac sodium double-release enteric capsules can more rapidly relieve joint pain, and improve the clinical efficacy. This combination therapy also has certain advantages in relieving joint swelling and improving the mobility function of the joint. Hence, this is worthy of clinical promotion and application.
Value chain analysis of Mung Bean (Vigna radiata L. Wilczek thrive) in Kalu Woreda, Ethiopia
Authors: Assefa Zena Befkadu , Dinku Amare Molla , Jemal Abdulkerime Mohammed 
Published: November 2022

AbstractBackgroundMung bean is an important pulse legume multipurpose crop that has significant health and economic benefits. It plays an important role in climate resilience and increasing food security. We conducted the study in Kalu Woreda Eastern Amhara, Ethiopia, where the crop is highly adopted. The study aimed to analyse and evaluate the local value chain of the crop. Though Mung bean is a market oriented crop and playing an important role in food and nutrition security; there is a lack of clear evidence that shows how the local value chain of the crop is performing. Therefore, empirical evidence on the Mung bean value chain is required to design interventions to enhance the value chain actors’ performance.MethodsA mixed approach was used to collect and analyse the data and to have a complete picture of the research. We collected data from producers, collectors, wholesalers, retailers, and exporters through household survey, focus group discussion and key informant interviews. Descriptive statistics and econometric model were used to analyse the quantitative data. We analysed qualitative data using narration, summarization, and theme formation.Results and conclusionThe average allocated land for Mung bean per household was 0.32 ha with a standard deviation of 0.15 ha. Mung bean value chain actors include input suppliers, producers, collectors, retailers, wholesalers, exporter and consumers. The highest percentage of the profit share goes to exporters (25.04%), followed by wholesalers (21.61%). Traditional farming practices, small landholding, poor access to agricultural inputs, pests and disease, poor infrastructure, and price fluctuations were the major Mung bean production and marketing challenges. Sex 0.166 (P = 0.008), the volume of Mung bean produced 0.26 (0.0001), farming experience 0.028 (0.048), frequency of extension contact 0.01 (0.072) and land allocated for Mung bean 3.411 (0.0001) were significantly determining the amount of Mung bean supplied to the market. Supporting farmers with agricultural inputs and delivering training on post-harvest issue, experience sharing among producers, and linking producers to cooperatives looks important to develop Mung bean local value chain. Strengthening multi-stakeholder linkages among Mung bean value chain actors through field days and workshops is also imperative in smoothing the local and international marketability of the crop.
Training effect on sex-based differences in components of the Shepard and Metzler mental rotation task
Authors: Kozaki Tomoaki 
Published: November 2022

Abstract
Background
Spatial ability has been reported to indicate sex-based differences in humans, mainly assessed by Shepard and Metzler mental rotation task (SM-MRT). Most performances in earlier studies have been evaluated by the mean value of reaction time and/or accuracy. The performance indexes might not be sensitive measures of mental rotation. Sex-based differences in the performance might also be involved in the spatial experience of the subject at the time. This study observed variations in components of the SM-MRT over repetition.

Methods
Male (n = 17) and female (n = 17) subjects completed 20 days of repeating the SM-MRT. The slope and intercept of the function performance (reaction time) to the angular disparity are calculated; the slope of this function indexes the mental rotation (main-process), and the intercept indexes the other sub-processes.

Results
A significant main effect of sex was obtained on the slope. The intercept also showed a tendency toward statistical difference. The interactions between the sexes and the day were not significant for the indices. Statistical testing for coefficient of variations (CV) indicated no sex-based difference in the effect of the intercept throughout the experiment day. The CV of the slope, however, showed tendencies toward sex-based difference from days 7 to 12.

Conclusions
The difference between the sexes in performance on the slope was sustained throughout the experimental period. A few female subjects who demonstrated larger slope values than male subjects caused the sex difference. The learning rate of mental rotation may be an inherent spatial ability.
Interplay of greening and ENSO on biosphere–atmosphere processes in Australia
Authors: Liang Shijing , Ziegler Alan D. , Li Laurent Z. X. , Wu Jie , Wang Dashan , Zeng Zhenzhong 
Published: November 2022

AbstractTerrestrial ecosystems are fully coupled with the climate. The planet has been greening owing to the increased vegetation growth in response to the changing atmosphere, which in turn has feedback on the climate. Greening has slowed down the rise in global land-surface air temperature mainly through a coincident increase of evapotranspiration and precipitation in wet regions. In dry regions, greening intensifies the decrease in soil moisture induced by greening-enhanced transpiration. Uncertain, however, is how the climate effects of greening in semi-arid lands might differ for variable wet and dry conditions. Here, we focus on the biosphere–atmosphere interactions in Australia by modeling the perturbation of vegetation changes under various states of sea surface temperature (SST), including the climatology mean, El Niño, and La Niña conditions. For the dry conditions of El Niño, greening exacerbates water stress and largely depletes the soil moisture, while for the wet conditions of La Niña, greening-enhanced evapotranspiration and precipitation resupply the soil moisture. For the normal conditions using the climatology mean SST, a small decrease in soil moisture occurs but with large spatial contrast because of heterogeneous changes of evapotranspiration and precipitation induced by greening. We emphasize that the alternating dry and wet conditions modulated by the large-scale climate variability are vital to understanding the response of climate to greening. Furthermore, vegetation-based warming mitigation policies need to be cautious when inferring distinct climate effects associated with greening.
Association between 1st trimester diet quality & gestational weight gain rate among pregnant women in Dhulikhel, Nepal
Authors: Martin Kelly , Radler Diane Rigassio , Sackey Joachim , Zhang Cuilin , Shrestha Kusum , Shrestha Abha , Shrestha Archana , Barrett Emily S. , Rawal Shristi 
Published: November 2022

Abstract
Background
Despite promising data from high-income countries, the impact of diet quality on gestational weight gain (GWG) has not been investigated in the context of many low-income countries including Nepal.

Methods
We prospectively examined the association between 1st trimester diet quality and GWG rate among a cohort of singleton pregnant women (n = 101; age 25.9 ± 4.1 years) from a community-based periurban hospital in Dhulikhel, Nepal. Diet quality was assessed from the adapted Nepali version of the 21-item PrimeScreen questionnaire in the 1st trimester. The diet quality score is based on consumption frequency of 21 food group components (score ranging 0–42), categorized as healthy (12 groups) versus unhealthy (9 groups), with higher scores indicative of better overall diet quality. The GWG rate was calculated as the measured weight at early-to-mid 3rd trimester (28–35 wks) minus the weight at 2nd trimester (13–25 wks), divided by the number of weeks in between. Linear regression estimated the association between diet quality and GWG rate, adjusting for a priori covariates (i.e. age, education, ethnicity, pre-pregnancy BMI, and nausea/vomiting.)

Results
The mean GWG rate in mid-to-late pregnancy was 0.46 ± 0.2 kg/wk and the mean diet quality score was 23.6 ± 2.5. Based on pre-pregnancy BMI, 49.4% of women had excessive GWG rate, while nearly equal numbers had either adequate GWG or inadequate GWG rate. There was no significant association between diet quality and GWG rate [adjusted β (95% CI) = -0.02 (-0.05, 0.01); p = 0.14]. The mean GWG rate was marginally higher (0.57 vs. 0.44 kg/wk; p = 0.06) among those with high versus low (2 + servings vs. 0–1 serving/wk) intake of red meat; similar findings were seen when comparing red meat intake between women with excessive versus adequate GWG (Cramer's V = 0.2; p = 0.06).

Conclusions
While 1st trimester diet quality is not related to GWG among Nepali women, a high intake of red meat may be a potential risk factor for excessive GWG in this population.
Adherence to dietary approaches to stop hypertension (DASH) diet in relation to psychological function in recovered COVID-19 patients: a case–control study
Authors: Khorasanchi Zahra , Ahmadihoseini Asieh , Hajhoseini Omalbanin , Zare-Feyzabadi Reza , Haghighi Masoumeh , Heidari Masoumeh , Esfehani Ali Jafarzadeh , Dehnavi Zahra , Sharifan Payam , Rashidianyazd Simin , Latifi MohammadReza , Rastgooy Fatemeh , Ildarabadi Danial , Bajgiran Maryam Mohammadi , Soflaei Sara Saffar , Ferns Gordon , Mobarhan Majid Ghayour 
Published: November 2022

Abstract
Background
Follow-up of patients after recovery from coronavirus disease 2019 (COVID-19) and identifying the adverse effects of the disease in other organs is necessary. Psychiatric symptoms can persist after patients recover from the infection.

Aim
We aimed to examine the adherence to the dietary approach to stop hypertension (DASH) diet in relation to psychological function in individuals who have recovered from COVID-19.

Method
This case–control study was conducted on 246 eligible adults (123 cases and 123 controls). A valid and reliable food frequency questionnaire (FFQ) was used to determine dietary intake. Depression, anxiety and stress, insomnia, sleep quality, and quality of life of participants were evaluated using DASS, Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), and SF-36 questionnaires, respectively.

Results
There was a significant inverse correlation between total depression score with vegetables, depression, anxiety, and stress score and dietary intake of nuts, legumes, and whole grains (p < 0.05). There was a significant positive correlation between stress scores and the intake of red and processed meat (P < 0.05). In multivariate-adjusted regression model, a significant association was found between adherence to DASH diet and depression and stress only in case group (OR = 0.7863, 95% CI 0.746–0.997, p = 0.046 and OR = 0.876, 95% CI 0.771–0.995, p = 0.042, respectively).

Conclusion
Adherence to a DASH diet might be associated with depression and stress reduction in recovered COVID-19 patients.
Obliterated Materiality: The Supremacy of the Book and Chosŏn Funerary Texts
Authors: Cho Hwisang 
Published: November 2022

AbstractThe deaths of Confucian scholars in the Chosŏn period (1392–1910) gave rise to elaborate rituals through which the bereaved reframed their relationships to the deceased as well as among themselves, and which took place most explicitly in the process of producing diverse funerary texts. Created in a specific material format and aesthetic, each funerary text addressed a particular group of people enacting its respective performative functions in the ritual proceedings. While exploring the funerary texts produced for T’oegye Yi Hwang (1501−1570), this article grapples with the indistinguishable narrative styles shown in different funerary texts despite their distinctive material conditions and ritual functions. It demonstrates that the privileged status that books enjoyed in Chosŏn Confucian tradition meant that their addressivity nullified the original tone and style of each text, because funerary texts were eventually compiled and included as part of the deceased’s collection of writings in book form. This study argues that textual scholarship needs to account for hierarchies among the different textual materialities, particularly when the same texts travel across diverse media forms. It complements existing historiography that almost always uses Chosŏn funerary texts as narrative sources and takes for granted the cultural practice of writing and including them in books.