bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of genotype diversity of 7,804 norovirus sequences in humans and animals of China
Authors: Li Manyu , Li Kejian , Lan Haiyun , Hao Xiaotian , Liu Yan , Zhou Cheng 
Published: November 2022

Abstract
Norovirus is a prominent enteric virus responsible for severe acute gastroenteritis disease burden worldwide. In our current study, we analyzed 7,804 norovirus sequences of human and animals in China which were detected from 1980 to 2020 from GenBank. The GenBank database was searched up to May 2021 with the following search terms: “norovirus” or “norwalk virus” and “China.” The 7,804 norovirus sequences were collected and evaluated by phylogenetic analysis using MEGA X software package. The online typing tool (https://www.rivm.nl/mpf/typingtool/norovirus/) was used to confirm the genotypes. There were 36 norovirus genotypes prevailing in China. GII.4 was the most prevalent genotype, and GII.2, GII.3 and GII.17 also emerged during different time periods. Most sequences were detected in East China (41.72%, 3,256/7,804), but different norovirus genotypes were distributed widely across the country. A variety of norovirus genotypes, including GI, GII, GIII, GIV, GV, GVI, GVII and GX, were reported in different animals. Furthermore, a GI.3 sequence detected from animal had high identity with norovirus detected in human from the same region, indicating the potential norovirus zoonotic transmission in China. In conclusion, these results indicated that norovirus sequences with considerable genetic diversity distributed widely in China, with potential reverse zoonotic transmission from human to animals.
An overview of the most important preanalytical factors influencing the clinical performance of SARS-CoV-2 antigen rapid diagnostic tests (Ag-RDTs)
Authors: Lippi Giuseppe , Henry Brandon M. , Plebani Mario 
Published: November 2022

Abstract
Due to the many technical limitations of molecular biology, the possibility to sustain enormous volumes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) diagnostic testing relies strongly on the use of antigen rapid diagnostic tests (Ag-RDTs). Besides a limited analytical sensitivity, the manually intensive test procedures needed for performing these tests, very often performed by unskilled personnel or by the patients themselves, may contribute to considerably impair their diagnostic accuracy. We provide here an updated overview on the leading preanalytical drawbacks that may impair SARS-CoV-2 Ag-RDT accuracy, and which encompass lower diagnostic sensitivity in certain age groups, in asymptomatic subjects and those with a longer time from symptoms onset, in vaccine recipients, in individuals not appropriately trained to their usage, in those recently using oral or nasal virucidal agents, in oropharyngeal swabs and saliva, as well as in circumstances when instructions provided by the manufacturers are unclear, incomplete or scarcely readable and intelligible. Acknowledging these important preanalytical limitations will lead the way to a better, more clinically efficient and even safer use of this important technology, which represents an extremely valuable resource for management of the ongoing pandemic.
Dry shrinkage of Moso bamboo in relation to vascular bundle structure
Authors: Zhang Ying , Xu Haocheng , Li Jing , Zhong Tuhua , Wang Hankun 
Published: November 2022

Abstract
Bamboo is susceptible to moisture-induced dimensional instability and cracking. Combining traditional methods with vascular bundle detection, the coordinates and fiber sheath area of each vascular bundle was determined accurately. Based on data fitting, the change in the shape of cross-section was quantified and analyzed based on parameters such as radius, radian, and arc length. The changes in the total area and the areas of different types of fiber sheath, as well as the changes in the arrangement of vascular bundles were studied. The results showed that when the moisture content was reduced from 64% to 0%, the radius of the cross section was increased by 21%, while the radian and arc length decreased by 22% and 6%, respectively. The fibers shrunk by 15%, which was greater than that of the other tissues except bamboo fibers (9%). The gradient distribution of the fiber volume fraction contributed to its asynchronous dry shrinkage. Significant radial and tangential displacements were found in vascular bundles. This work further elucidated the dry shrinkage mechanism of bamboo, and was of great significance for the quantitative analysis of changes in bamboo structure from a combination of micro and macro perspectives.
Moroccan Arabic in TV fiction: promoting de-localised individuals to model speakers
Authors: Falchetta Jacopo 
Published: November 2022

AbstractThis paper aims at clarifying the role that TV fiction plays in the indexical redistribution of Moroccan Arabic (MA) linguistic features, and how this is connected to media’s contribution to the non-institutional standardisation of MA. First of all, it shows how six variables are employed in the composition of dialogues for two original Moroccan series and two Turkish series dubbed in MA. In the Moroccan series, the assignment of different features to different characters results in the enregisterment of a linguistic opposition between two social types, distinguished by their attachment to place of origin and attitudevis-à-vismodernity. In the dubbed series, standardisation is at issue in that the authors of the linguistic choices – be they the translators or the dubbers – usually select one single form to the exclusion of all other variants. If this selection of a MA norm is judged on the background of the enregisterment patterns identified in the dialogues of the Moroccan series, it then appears as though such norm favours a type of individual free from particularistic regional affiliations, and with a propensity for an anti-traditionalist and (western-like) modern lifestyle and way of thinking.
The Jebli speech between the media and the city: exploring linguistic stereotypes on a rural accent in Northern Morocco
Authors: Benítez Fernández Montserrat , Guerrero Jairo 
Published: November 2022

AbstractThe symbolic values that speakers attribute to certain linguistic features constitute an important sociolinguistic topic which, barring a few seminal works, has not drawn much attention from scholars working on Maghrebi Arabic, and more specifically, Moroccan varieties. The present paper aims to deepen our understanding of metalinguistic representations of Jebli, a sedentary rural variety of Moroccan Arabic, within the speech communities of Larache and Ouezzane, two urban centres lying on the southern periphery of the Jbala region of Northern Morocco. We first analysed several samples of performed speech taken from an online Moroccan comedy sketch series entitledJebli & Beldi, which includes a character epitomizing the Jebli accent, in order to identify those salient linguistic features that are perceived as being typically Jebli. As these phonetic and morphosyntactic traits are consciously selected in performed speech, it may be assumed that they make up a linguistic stereotype. We then asked a group of informants in the cities of Larache and Ouezzane to describe what they regarded as the typical features of Jebli speech and also their attitudes towards these features. The results of our study show that the features informants named partly coincided with our own sketch-based selection, and their attitudes towards these features were generally negative. These features did not appear in the speech of most informants, suggesting either their absence in their dialect or a deliberate avoidance strategy on their part. A small number in fact used these features but denied doing so, suggesting that the features are socially stigmatized. We argue that the symbolic values ascribed to some typical Jebli features may trigger their avoidance, which in turn may generate linguistic variation and even lead to linguistic change.
Machine learning models can predict the presence of variants in hemoglobin: artificial neural network-based recognition of human hemoglobin variants by HPLC
Authors: Uçucu Süheyl , Karabıyık Talha , Azik Fatih Mehmet 
Published: November 2022

Abstract

Objectives
This article presents the use of machine learning techniques such as artificial neural networks, K-nearest neighbors (KNN), naive Bayes, and decision trees in the prediction of hemoglobin variants. To the best of our knowledge, this is the first study using machine learning models to predict suspicious cases with HbS or HbD Los Angeles carriers state.

Methods
We had a dataset of 238 observations, of which 128 were HbD carriers, and 110 were HbS carriers. The features were age, sex, RBC, Hb, HTC, MCV, MCH, RDW, serum iron, TIBC, ferritin, HbA2, HbF, HbA0, retention time (RT) of the abnormal peak, and the area under the peak of the abnormal peak. KNN, naive Bayes, decision tree models, and artificial neural network models were trained. Model performances were estimated using 7-fold cross-validation.

Results
When RT, the key point of differentiation used in high-performance liquid chromatography (HPLC), was included as a feature, all models performed well. When RT was excluded (eliminated), the deep learning model performed the best (Accuracy: 0.99; Specificity: 0.99; Sensitivity: 0.99; F1 score: 0.99), while the naive Bayes model performed the worst (Accuracy: 0.94; Specificity: 0.97; Sensitivity: 0.90; F1 score: 0.93).

Conclusions
Deep learning and decision tree models have demonstrated high performance and have the potential to be integrated into medical laboratory work practices as a tool for hemoglobinopathy detection. These outcomes suggest that when machine learning models are fed enough data, they can detect a wide range of hemoglobin variants. However, more comprehensive studies with data from a larger number of patients and hemoglobinopathies will be useful for validating our models.
Structure and properties of phases from solid solutions YTIn1−x
Al
x
(T = Ni and Cu)
Authors: Horiacha Myroslava , Nychyporuk Galyna , Bönnighausen Judith , Stegemann Frank , Pavlyuk Volodymyr , Pöttgen Rainer , Zaremba Vasyl’ 
Published: November 2022

Abstract
YNiIn and YCuIn form complete solid solutions YNiIn1−x
Al
x
and YCuIn1−x
Al
x
, which were characterized on the basis of X-ray powder diffraction. The ZrNiAl type crystal structures (space groups

P

6
‾

2
m

$P\overline{6}2m$

) of YNiAl (a = 0.70386(9), c = 0.38327(4) nm, wR
2 = 0.0424), YNiIn0.77Al0.23 (a = 0.73895(9), c = 0.37707(4) nm, wR
2 = 0.0498) and YCuIn0.63Al0.37 (a = 0.73404(7), c = 0.39045(4) nm, wR
2 = 0.0314) were refined from the single crystal X-ray diffraction data. Exemplarily the electronic structure of YNiAl was studied, manifesting substantial Ni–Al bonding within the three-dimensional [NiAl] substructure. Comparison of YNiAl with isotypic YNiIn shows stronger Ni–Al bonding as compared to Ni–In. Magnetic susceptibility measurements of YNiIn1−x
Al
x
(x = 0.1, 0.2, 0.7 and 0.9), YNiIn and YNiAl in the temperature range 3–300 K indicated Pauli paramagnetic behaviour with molar magnetic susceptibility of about 0.15–0.22 × 10−3 emu/mol.
Endoplasmic reticulum stress promotes endometrial fibrosis through the TGF-β/SMAD pathway
Authors: Bao Meng , Feng Qiwen , Zou Liping , Huang Jin , Zhu Changhong , Xia Wei 
Published: November 2022

In brief
Intrauterine adhesion (IUA) is one of the main causes of female infertility. This study reveals that endoplasmic reticulum stress activation upregulates the TGF-β/SMAD pathway to induce epithelial–mesenchymal transition and promote endometrial fibrosis in an IUA model.

Abstract
IUA is a common gynecological disease and is a leading cause of female infertility. Mechanical or infectious damage to the endometrial basal layer can lead to endometrial fibrosis, which is the most common cause of IUA. Endoplasmic reticulum stress (ERS), the transforming growth factor beta signaling pathway (TGF-β/SMAD) and epithelial–mesenchymal transition (EMT) are important factors promoting endometrial fibrosis. The purpose of this study was to determine the up- and downstream regulatory relationships of the above three in the process of endometrial fibrosis. The rat IUA model was induced by double injury method and prophylactic injection of the ERS inhibitor 4-phenylbutyric acid (4-PBA) was given in vivo. The ERS activator tunicamycin and the TGF-β/SMAD pathway inhibitor A 83-01 were used in human endometrial epithelial cells (HEECs) in vitro. Masson’s trichrome, Sirius red staining, immunohistochemistry, immunofluorescence and Western blot analyses were used to determine ERS, TGF-β/SMAD pathway, EMT and fibrosis markers in the uterine tissue and HEECs of the different treatment groups. In animal experiments, ERS and the TGF-β/SMAD pathway had been activated and EMT occurred in an in vivo model of IUA but was suppressed in animals treated with prophylactic 4-PBA. In in vitro experiments, tunicamycin-treated HEECs had increased the activation of ERS, the abundance of TGF-β/SMAD pathway and fibrosis markers while EMT occurred, but the TGF-β/SMAD pathway and EMT were significantly inhibited in the tunicamycin+A 83-01 group. Our data suggest that increased ERS can induce EMT and promote endometrial fibrosis through the TGF-β/SMAD pathway.
A corpus-based search for machine translationese in terms of discourse coherence
Authors: Jiang Yue , Niu Jiang 
Published: November 2022

AbstractEarlier studies have corroborated that human translation exhibits unique linguistic features, usually referred to as translationese. However, research on machine translationese, in spite of some sparse efforts, is still in its infancy. By comparing machine translation with human translation and original target language texts, this study aims to investigate if machine translation has unique linguistic features of its own too, to what extent machine translations are different from human translations and target-language originals, and what characteristics are typical of machine translations. To this end, we collected a corpus containing English translations of modern Chinese literary texts produced by neural machine translation systems and human professional translators and comparable original texts in the target language. Based on the corpus, a quantitative study of discourse coherence was conducted by observing metrics in three dimensions borrowed from Coh-Metrix, including connectives, latent semantic analysis and the situation/mental model. The results support the existence of translationese in both human and machine translations when they are compared with original texts. However, machine translationese is not the same as human translationese in some metrics of discourse coherence. Additionally, machine translation systems, such as Google and DeepL, when compared with each other, show unique features in some coherence metrics, although on the whole they are not significantly different from each other in those coherence metrics.
Autonomy support, critical thinking, and motivation as key predictors of translator trainees' strategic competence
Authors: Bolaños-Medina Alicia , Núñez Juan L. 
Published: November 2022

AbstractThis study consists of a correlational and regression analysis of certain factors involved in the practice of translator training, as perceived by translator trainees. More precisely, our aim is to examine the relationships between translator trainees' strategic competence (as the dependent variable), and autonomy support, amotivation and critical thinking (as the independent variables) in the translation classroom. Building upon recent advances in educational and social psychology, we have relied on Self-determination theory (Deci & Ryan, 2011) as an interpretative frame of reference. After revising the concept of translators' strategic competence, the main contributions in the field of translators' motivation are also reviewed and the notions of autonomy support and critical thinking are approached from the perspective of both psychology and translatology. Our findings seem to point to the fact that autonomy support and critical thinking can play a facilitating role in the development of strategic competence in undergraduate translator students, who may also benefit from both when they encounter new challenges in real professional settings. Finally, the implications for translator training are discussed.
Сellular composition and cytokine profile of synovial fluid in rheumatoid arthritis
Authors: Zhdanova E. V. , Kostolomova E. G. , Volkova D. E. , Zykov A. V. 
Published: November 2022

Rheumatoid arthritis (RA) ranks first among chronic joint diseases. The disease often affects people at their working age, being accompanied by significant decrease in the life quality of patients and their early disability. Rheumatoid arthritis is an immunoinflammatory rheumatic disease. Therefore, the immune system provides evolving focus of primary damage, its persistence and periodic exacerbation. Elucidation of intercellular relationships mediated by cytokines at various stages of the chronic inflammatory process is required in order to develop immunotherapeutic approaches, aimed for both recovery from exacerbations and maintenance of remission state. Purpose of our study was to evaluate cellular composition and cytokine profile of synovial fluid in the patients with rheumatoid arthritis at acute phase and in remission state.We have studied the samples of synovial fluid taken in 60 patients with rheumatoid arthritis, with 30 subjects being at acute stage of the disease, and 30 patients in remission. Cellular composition and cytokine profile were assessed in the clinical samples. There were 21 women and 9 men at the acute stage (57.0±15.4 years old), with the disease duration of 8.55±6.9 years. The average age of 19 women and 11 men examined in remission state was 53.5±10.9 years, with comparable duration of illness (6.9±5.8 years). The leukocyte phenotyping was performed with a CytoFLEX flow cytometer (Beckman Coulter, USA). The cytokine contents were measured by enzyme immunoassay using a standard set of reagents from the “Proteinovy Contour” LLC (Russia). The results were registered by a Multiscan photometer (Labsystems, Finland).During the disease exacerbation, the leukocyte contents in synovial fluid increased 2.4-fold, as compared to the remission values. The cellular infiltrate was represented by neutrophils, whereas the contents of lymphocytes and monocytes did not change. Increased migration of neutrophils was accompanied by an 8-fold increase in TNFα levels, compared with remission state, and IL-1β levels were increased by 6.3 times. The absolute number of CD3+T lymphocytes, CD16+CD56+B cells, and CD3-CD19+NK during exacerbation was similar to the remission levels. However, the number of T cell subpopulations was changed, i.e., the number of CD4+ lymphocytes was decreased, and CD8+ cell counts were increased, like as numbers of Treg lymphocytes and NKT cells which showed a significant increase. A 4.3-fold increase in the IL-4 concentration during the RA exacerbation suggested the predominance of Th2 immune response. During remission, the concentrations of IL-6 and IFNγ in synovial fluid were increased, respectively, by 1.5 times and by 2.5 times, which is typical for activated Th1 response.
Abundancia y nuevos registros de búhos simpátricos en Manizales y Villa María (Caldas, Colombia)
Authors: Restrepo Cardona Juan Sebastián , Betancur López Alejandro , Cano Castaño Nelson 
Published: November 2022

Los estudios sobre abundancias de especies en comunidades de búhos neotropicales en ambientes urbanos y periurbanos son pocos. Entre mayo y septiembre de 2013 se estimó la abundancia relativa de búhos simpátricos, realizando conteos de llamados espontáneos a través de recorridos en trayectos, y se calculó el porcentaje de registros de cada especie en distintos tipos de vegetación, en cuatro localidades de Manizales (Caldas, Colombia). Además, se documentaron nuevos registros de ocho especies de búhos en 17 localidades en Manizales y Villamaría. En los recorridos se detectaron cuatro especies de búhos: Ciccaba virgata, Megascops choliba, Asio stygius y Tyto alba. Las especies registradas de mayor a menor abundancia relativa fueron: en La Esmeralda, A. stygius (0,37 No. ind./km recorrido), A. stygius, C. virgata y T. alba (0,02); en El Recinto del Pensamiento, C. virgata (0,37), A. stygius, A. stygius y T. alba (0,05), en El Bosque Popular El Prado, A. stygius (0,84), C. virgata y T. alba (0,03), y en El Ecoparque Alcázares, C. virgata (0,74) y A. stygius (0,10). C. virgata fue registrada en todos los tipos de vegetación, aunque el mayor número de registros de esta especie se obtuvo en los bosques asociados a áreas abiertas para la recreación. A. stygius fue registrada en cuatro tipos de vegetación, con un mayor número de registros en las áreas abiertas con árboles maduros. La baja sensibilidad a las perturbaciones por parte de C. virgata y A. stygius, y su adaptabilidad para ocupar un amplio número de ambientes podría favorecerlas para alcanzar los mayores niveles de abundancia entre los búhos de Manizales. A. stygius y T. alba se registraron con mayor frecuencia en las plantaciones de pino.
Colonización de macroinvertebrados acuáticos en hojas de Miconia sp. y Eucalyptus sp. en la subcuenca alta del río Chinchiná, Colombia
Authors: Rubio M. Juliana , Meza S. Ana María , Gomes Dias Lucimar 
Published: November 2022

Los procesos de colonización en ambientes lóticos son regulados por la interacción entre el tipo de vegetación y la cantidad de hojarasca que se incorpora a los ríos e influye sobre la estructura y dinámica del bentos. Los macroinvertebrados bentónicos son un componente importante en los ecosistemas dulceacuícolas, cumplen un papel fundamental en la descomposición y recirculación de nutrientes, además de contribuir en la red trófica como alimento de otros animales. Con el objetivo de comparar la colonización de macroinvertebrados en hojas de árboles nativos e introducidos a través del tiempo en las quebradas El Diamante, La Oliva y el río Chinchiná, se utilizó la metodología de paquetes de hojarasca. La primera quebrada presenta como vegetación ribereña un bosque nativo, la segunda está influenciada por plantaciones de Eucalyptussp. y la tercera no presenta vegetación ribereña. Para el estudio se utilizaron paquetes de tela plástica, donde fueron depositadas hojas de Miconia sp. (especie nativa), hojas de Eucalyptussp. y una mezcla de las dos especies, las cuales demoraron aproximadamente 60 días para descomponerse. En total, se colectaron 8595 individuos de macroinvertebrados, la menor riqueza se presentó a los 30 días y la mayor entre los 45 y 60 días. No se encontraron diferencias significativas en la riqueza y abundancia de macroinvertebrados con respecto a las dos especies vegetales utilizadas. Al evaluar la diversidad (q=0, q=1) no se encontraron diferencias significativas en el número efectivo de géneros o morfotipos entre sustratos (paquetes con hojas nativas, introducidas y mezcladas). El grupo funcional de los recolectores generalistas fue dominante entre los macroinvertebrados colectados.