bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mining World Indicators for Analyzing and Modeling the Development of Countries
Authors: Huang Hong , Chi Mingyuan , Song Yu , Jin Hai 
Published: March 2022

The world indicators released by the World Bank or other organizations usually give the basic public knowledge about the world. However, separate and static index lacks the complex interplay among different indicators and thus cannot help us have an overall understanding of the world. To this end, we study the world indicators from a different angle. Firstly, we discover that there exist correlations between indicators either from a static view or from a dynamic view. Moreover, taking the trade and diplomatic relationships into consideration, we construct a multi-relational network to depict the interactions between different countries, and propose a Multiple Relations to Vector (MR2vec) model to study world indicators from a network perspective. The experimental results show the changes of world indicators are predictable with the proposed model, and our proposed MR2vec has wide adaptability in predicting multi-relation networks.
Time Dependent Biased Random Walks
Authors: Haslegrave John , Sauerwald Thomas , Sylvester John 
Published: March 2022

We study the biased random walk where at each step of a random walk a “controller” can, with a certain small probability, move the walk to an arbitrary neighbour. This model was introduced by Azar et al. [STOC’1992]; we extend their work to the time dependent setting and consider cover times of this walk. We obtain new bounds on the cover and hitting times. Azar et al. conjectured that the controller can increase the stationary probability of a vertex from
p
to
p
1-ε
; while this conjecture is not true in full generality, we propose a best-possible amended version of this conjecture and confirm it for a broad class of graphs. We also consider the problem of computing an optimal strategy for the controller to minimise the cover time and show that for directed graphs determining the cover time is
PSPACE
-complete.
Plasma Growth Factor Gene Expression and Mammographic Breast Density in Postmenopausal Women
Authors: Akinjiyan Favour A. , Adams Andrea , Xu Shuai , Wang Mei , Toriola Adetunji T. 
Published: March 2022

Abstract

Mammographic breast density (MBD) is a risk factor for breast cancer, but its molecular basis is poorly understood. Growth factors stimulate cellular and epithelial proliferation and could influence MBD via these mechanisms. Studies investigating the associations of circulating growth factors with MBD have, however, yielded conflicting results especially in postmenopausal women. We, therefore, investigated the associations of plasma growth factor gene expression [insulin-like growth factor (IGF)-1, IGF-binding protein 3, FGF-1, FGF-12, TGFβ1 and bone morphogenetic protein (BMP)-2] with MBD in postmenopausal women. We used NanoString nCounter platform to quantify plasma growth factor gene expression and Volpara to evaluate volumetric MBD measures. We investigated the associations of growth factor gene expression with MBD using both multiple linear regression (fold change) and multinomial logistic regression models, adjusted for potential confounders. The mean age of the 368 women enrolled was 58 years (range, 50–64). In analyses using linear regression models, one unit increase in IGF-1 gene expression was associated with a 35% higher volumetric percent density (VPD, 1.35; 95% confidence interval (CI), 1.13–1.60; P = 0.001). There were suggestions that TGFβ1 gene expression was positively associated with VPD while BMP-2 gene expression was inversely associated with VPD, but these were not statistically significant. In analyses using multinomial logistic regression, TGFβ1 gene expression was 33% higher (OR = 1.33; 95% CI, 1.13–1.56; P = 0.0008) in women with extremely dense breasts than those with almost entirely fatty breasts. There were no associations between growth factor gene expression and dense volume or nondense volume. Our study provides insights into the associations of growth factors with MBD in postmenopausal women and requires confirmation in other study populations.

Prevention Relevance:
Mammographic breast density is a strong risk factor for breast cancer. Understanding its underlying biological mechanisms could have utility in breast cancer prevention.
RETRACTED: In Vivo Monitoring of Polycythemia Vera Development Reveals Carbonic Anhydrase 1 as a Potent Therapeutic Target
Authors: Murakami Shohei , Barroca Vilma , Perié Leïla , Bravard Anne , Bernardino-Sgherri Jacqueline , Tisserand Amandine , Devanand Caroline , Edmond Valérie , Magniez Aurélie , Tenreira Bento Sabrina , Torres Claire , Pasquier Florence , Plo Isabelle , Vainchenker William , Villeval Jean-Luc , Roméo Paul-Henri , Lewandowski Daniel 
Published: March 2022

Abstract

Current murine models of myeloproliferative neoplasms (MPNs) cannot examine how MPNs progress from a single bone marrow source to the entire hematopoietic system. Thus, using transplantation of knock-in JAK2V617F hematopoietic cells into a single irradiated leg, we show development of polycythemia vera (PV) from a single anatomic site in immunocompetent mice. Barcode experiments reveal that grafted JAK2V617F stem/progenitor cells migrate from the irradiated leg to nonirradiated organs such as the contralateral leg and spleen, which is strictly required for development of PV. Mutant cells colonizing the nonirradiated leg efficiently induce PV in nonconditioned recipient mice and contain JAK2V617F hematopoietic stem/progenitor cells that express high levels of carbonic anhydrase 1 (CA1), a peculiar feature also found in CD34+ cells from patients with PV. Finally, genetic and pharmacologic inhibition of CA1 efficiently suppresses PV development and progression in mice and decreases PV patients’ erythroid progenitors, strengthening CA1 as a potent therapeutic target for PV.

Significance:
Follow-up of hematopoietic malignancies from their initiating anatomic site is crucial for understanding their development and discovering new therapeutic avenues. We developed such an approach, used it to characterize PV progression, and identified CA1 as a promising therapeutic target of PV.
This article is highlighted in the In This Issue feature, p. 265
The Effect of Extra School Funding on Students’ Academic Achievements under a Centralized School Financing System
Authors: Sohn Hosung , Park Heeran , Jung Haeil 
Published: March 2022

Abstract
This paper analyzes the effect of providing extra school funding on student achievement under the homogenous school funding system in South Korea. This study exploits an administrative cutoff rule that determines the provision of school funding and uses a regression discontinuity design to identify a causal impact of extra school funding. The analysis finds that a 20 percent increase in per pupil funding for underperforming schools reduced the number of below-average students in mathematics, English, social studies, and science by 19.7 percent, 17.0 percent, 16.1 percent, and 18.1 percent compared with the control-side means. The research findings suggest that additional funding for underperforming schools to promote vertical equity would improve students’ academic outcomes if it is distributed directly to underperforming schools and used to provide new academic programs to students.
A Small State’s Campaign to Get Elected to the UNSC: Iceland’s Ambitious Failed Attempt
Authors: Thorhallsson Baldur , Elínardóttir Jóna Sólveig , Eggertsdóttir Anna Margrét 
Published: March 2022

Summary
This article provides a case study of a small state, Iceland, and its motives for running for a seat on the UN Security Council for the 2009-2010 term, the domestic dispute about the affair, key campaign messages and the campaign strategy. The article fills a gap in the international relations and small state literature on small states’ campaign strategies in UNSC elections. We conclude that the decision to run for a seat and the core message of the campaign were largely based on the quest to enhance Iceland’s status among international actors. However, the country’s lack of resources, limited international engagement and domestic debate about the candidacy became a hindrance. Iceland succeeded in using its smallness to build good momentum for its candidacy but in the end it failed due to weaknesses associated with its small size and its lack of contributions, competence and ideational commitment in the UN.
The microstructure of Moso bamboo (Phyllostachys heterocycla) with tung oil thermal treatment
Authors: Tang Tong , Sui Zhen , Fei Benhua 
Published: March 2022

Summary
Bamboo has a natural anisotropic porous structure. Previous studies have shown strong correlations between the properties and microstructure of bamboo. In this study, we examined the microstructure of Moso bamboo to reveal the mechanism of enhanced properties with tung oil thermal treatment. The morphological and chemical microstructure of Moso bamboo were characterized using scanning electron microscopy (SEM) and Raman spectroscopy. We found that tung oil film presented in the cell wall, cell lumen, and intercellular space after tung oil thermal treatment, which could decrease the water permeability in the cell wall. Additionally, the pits in vessels showed significant shrinkage in the short-axis orientation with thermal treatment in tung oil, and the shrinkage rate was nearly 50% with a temperature of tung oil over 140°C, which prevented the transportation of water through the pit. The content of tung oil in bamboo was reduced by more than 50% with an increase of tung oil temperature from 140°C to 200°C, which further supported the results of changed bamboo morphology. Altogether, these findings offer further support for the enhanced hydrophobic property of bamboo after tung oil thermal treatment.
The damselfly genus Megaloprepus (Odonata: Pseudostigmatidae): Revalidation and delimitation of species-level taxa including the description of one new species
Authors: FEINDT WIEBKE , HADRYS HEIKE 
Published: March 2022

As the longest-winged odonate species of the extant world, Megaloprepus caerulatus (Drury, 1782) has received attention by many entomologists. While the behavior and ecology of this species has been subject of intense studies, biogeography and species status throughout its distributional range in old-growth Neotropical forests are less well known. For tropical forests, this information is a sine qua non when estimating the impact of degradation and climate change. Recent population genetic analyses, quantitative morphometric, and traditional taxonomic studies rediscovered a complex composed of cryptic species within the genus Megaloprepus Rambur, 1842—up until now still regarded as a monotypic genus. Here we introduce one new species Megaloprepus diaboli sp. nov. from the southern Pacific coast of Costa Rica and from the central Caribbean coast of Honduras and Guatemala. The holotype is from the Corcovado National Park, Costa Rica (N 8°28’55.62” W 83°35’13.92”), and was deposited at the National Museum of Costa Rica. Aside from M. caerulatus, two formerly described and later refused species within the genus were reevaluated and consequently raised to species status: Megaloprepus latipennis Selys, 1860 is found in the northeastern regions of Mesoamerica and Megaloprepus brevistigma Selys, 1860 in South America east of the Andes. Morphological descriptions of selected specimens (holotype of M. diaboli, lectotype of M. latipennis, and the mature males of M. brevistigma and M. caerulatus) are provided. Diagnostic features of the four species are illustrated, discussed, and summarized in a key to adult males.
A contribution to understanding the morphology of the genus Anthroherpon (= Parantrophilon syn. nov.) and new combination for a species from the Balkan Peninsula (Insecta, Coleoptera, Leiodidae, Cholevinae, Leptodirini)
Authors: ČEPLÍK DÁVID , HLAVÁČ PETER 
Published: March 2022

The subterranean beetle genus Anthroherpon Reitter, 1889 stands for an iconic cave-adapted organism due to wide range of the morphological variability and the diversification of its species in the Central and Southern Dinarides. The monotypical genus Parantrophilon Noesske, 1914 is nested within the distribution area of Anthroherpon and it is also narrowly distributed. After a morphological study and comparison with the related material of the genus Anthroherpon Reitter, 1889, the synonymy of Parantrophilon to Anthroherpon is established. A redescription of the genus Anthroherpon Reitter, 1889 is given.
Possible Relationship between January “Warm Arctic–Cold Eurasia” and February Haze in North China
Authors: Zhang Yijia , Yin Zhicong , Zhou Botao , Wang Huijun 
Published: March 2022

Abstract
Haze pollution frequently occurs in North China almost every winter month. However, many previous studies pointed out that the interannual–decadal variations of haze in February were inconsistent with that in early winter, which demonstrated an evident subseasonal change in haze pollution. In this study, we found a close relationship between the “warm Arctic–cold Eurasia” (WACE) pattern in January and the weakened February haze pollution in North China according to monthly composites from 1980 to 2019. Associated with the warming signal in sea ice and the cooling signal in Eurasian soil temperatures, the WACE pattern sustained from January to February. The combined signal of sea ice and soil temperature anomalies and its associated anomalous cyclonic circulations over North China provided an environment conducive to the dispersion of pollutants. The relationship between the WACE pattern and the cyclonic circulation anomaly could also be detected from the large-ensemble CMIP6 simulations. Furthermore, the relationship between the January WACE pattern and the reduction of February haze pollution has been prominently enhanced since the late 1990s, which accurately corresponds to the deep Arctic warming that has emerged since the late 1990s.

Significance Statement
Haze pollution frequently occurs in North China almost every winter month, but with an apparent subseasonal change. Climate anomalies in the mid- to high latitudes could regulate the variations in haze through atmospheric teleconnection. Our study found a relationship between the “warm Arctic–cold Eurasia” (WACE) pattern in January and the weakened February haze pollution in North China. The lingering signal of the WACE was associated to the anomalous cyclonic circulations over North China in February, which was conducive to the dispersion of pollutants. Furthermore, the relationship between the WACE pattern and February haze pollution has been prominently enhancing since the late 1990s, which accurately corresponds to the emergence of the deep Arctic warming accompanied by the strengthened Eurasian cooling. This investigation is of great significance for subseasonal haze prediction.
Land–Snow Data Assimilation Including a Moderately Coupled Initialization Method Applied to NWP
Authors: Benjamin Stanley G. , Smirnova Tatiana G. , James Eric P. , Lin Liao-Fan , Hu Ming , Turner David D. , He Siwei 
Published: March 2022

Abstract
Initialization methods are needed for geophysical components of Earth system prediction models. These methods are needed from medium-range to decadal predictions and also for short-range Earth system forecasts in support of safety (e.g., severe weather), economic (e.g., energy), and other applications. Strongly coupled land–atmosphere data assimilation (SCDA), producing balanced initial conditions across the land–atmosphere components, has not yet been introduced to operational numerical weather prediction (NWP) systems. Most NWP systems have evolved separate data assimilation (DA) procedures for the atmosphere versus land/snow system components. This separated method has been classified as a weakly coupled DA system (WCDA). In the NOAA operational short-range weather models, a moderately coupled land–snow–atmosphere assimilation method (MCLDA) has been implemented, a step forward from WCDA toward SCDA. The atmosphere and land (including snow) variables are both updated within the DA using the same set of observations (aircraft, radiosonde, satellite radiances, surface, etc.). Using this assimilation method, land surface state variables have cycled continuously for 6 years since 2015 for the 3-km NOAA HRRR model and with CONUS cycling since 1997. Month-long experiments were conducted with and without MCLDA for both winter and summer seasons using the 13-km Rapid Refresh model with atmosphere (50 levels), soil (9 levels), and snow (up to 2 layers if present) on the same horizontal grid. Improvements were evident for 2-m temperature for all times of day out to 6–12 h for both seasons but stronger in winter. Better temperature forecasts were also shown in the 1000–900-hPa layer corresponding roughly to the boundary layer.

Significance Statement
Accuracy of weather models depends on accurate initial conditions for soil temperature and moisture as well as for the atmosphere itself. This paper describes a moderately coupled data assimilation method that modifies soil conditions based on forecast error corrections indicated by atmospheric observations. This method has been tested for a month-long period in summer and winter and shown to consistently improve short-range forecasts of 2-m temperature and moisture. This coupled data assimilation method is used already in NOAA operational short-range models to improve its prediction skill for clouds, convective storms, and general weather conditions.
Enhanced Recovery After Surgery Protocols for Head and Neck Cancer: Systematic Review and Meta‐analysis
Authors: Kattar Nrusheel , Wang Steven X. , Trojan Jeffrey D. , Ballard Craig R. , McCoul Edward D. , Moore Brian A. 
Published: March 2022

AbstractObjectiveEnhanced recovery after surgery (ERAS) protocols aim to optimize the pre‐, intra‐, and postoperative care of patients to improve surgery outcomes, reduce complications, decrease length of stay, and more. We aim to perform a systematic review and meta‐analysis of ERAS protocols for head and neck cancer surgery with or without microvascular reconstruction.Data SourcesPubMed, Embase, and Web of Science databases were queried, and abstracts were screened independently by 2 investigators.Review MethodsThis review was conducted in accordance with the PRISMA guidelines. We included comparative observational studies but excluded animal studies, case reports, and case series.ResultsOf 557 articles initially reviewed by title and/or abstract, we identified 30 for full‐text screening, and 9 met the criteria for qualitative synthesis. Meta‐analysis of length of stay revealed a mean decrease of 1.37 days (95% CI, 0.77‐1.96; I2 = 0%; P < .00001) with the ERAS group as compared with non‐ERAS controls. The standardized mean difference of the morphine milligram equivalent was 0.72 lower (95% CI, 0.26‐1.18; I2 = 82%; P = .002) in the ERAS group vs controls. The quality of studies was moderate with a median MINORS score of 18.5 (range, 13.5‐21.5).ConclusionImplementation of ERAS protocols can lead to decreases in length of stay and opioid drug utilization. However, further high‐quality prospective studies of ERAS protocols are needed, especially with stratified analysis of outcomes based on the type of head and neck cancer surgery.
Dysphagia Outcomes Following Surgical Management of Unilateral Vocal Fold Immobility in Children: A Systematic Review
Authors: Marvin Kastley , Coulter Michael , Johnson Christopher , Friesen Tzyynong , Morris Kimberly , Brigger Matthew T. 
Published: March 2022

AbstractObjectiveTo assess dysphagia outcomes following surgical management of unilateral vocal fold immobility in children.Data SourcesOvid Medline, Embase, Web of Science, and CENTRAL databases.Review MethodsA systematic review of the medical literature was performed following the PRISMA guidelines. An a priori protocol was defined to identify all articles that presented quantifiable outcome data in children aged <18 years who underwent surgical treatment to improve glottal competence for dysphagia. Two authors independently determined references meeting the inclusion criteria, extracted data, and assigned levels of evidence. Data were pooled via a random effects model where possible. The quality of studies was graded with the MINORS criteria.ResultsAn overall 398 publications were screened, with 9 meeting inclusion criteria. A total of 115 patients were included. Of these, 75% had preoperative swallowing symptoms. Surgical intervention for dysphagia included 61 injection laryngoplasties, 11 medialization laryngoplasties, and 10 reinnervations (ansa cervicalis to recurrent laryngeal nerve). The articles consistently reported success in improving dysphagia symptoms, and limited meta‐analysis demonstrated a mean improvement after surgical intervention in 79% (95% CI, 67%‐91%) of children. The reported rate of minor and major complications was 15% (95% CI, 1%‐29%). The MINORS scores ranged from 5 to 12.ConclusionSurgical management of unilateral vocal fold immobility in properly selected children can be an effective treatment for dysphagia when symptoms are present. Selection of surgical modalities relies on patient‐ and surgeon‐related factors, and the rate of success is high across different interventions in treating these complex children.
Attitude and practice toward traditional medicine among hypertensive patients on follow-up at Mizan–Tepi University Teaching Hospital, Southwest Ethiopia
Authors: Aferu Temesgen , Mamenie Yalew , Mulugeta Meseret , Feyisa Diriba , Shafi Miftah , Regassa Tolcha , Ejeta Fikadu , Hammeso Workineh Woldeselassie 
Published: March 2022

Introduction: Traditional medicine has been used for the management of common mild conditions such as headache, diarrhea, and common cold as well as in the treatment of chronic diseases including hypertension. The usage of this medicine is regarded as acceptably safe with most Ethiopian people. Attitude and practices toward traditional medicine are crucial elements of hypertension control and its favorable outcome expectation. This study aimed at assessing the attitude and practice toward traditional medicine among hypertensive patients on follow-up at Mizan–Tepi University Teaching Hospital, Southwest Ethiopia. Method: Facility-based cross-sectional study was conducted from 1st December 2020 to 30th December 2020 among 173 hypertensive patients. A consecutive sampling technique was used to select study participants. Data were collected through interviewer-administered structured questionnaire and analyzed using Statistical Package for the Social Sciences software version 23. Multivariable logistic regression analysis was done to identify the independent predictors of patients’ attitude toward traditional medicine and their traditional medicine use at a p value ⩽0.05. Results: Eighty-seven (50.29%) of the total 173 approached patients were found to have good attitude toward traditional medicine. Ninety-seven (56.07%) participants had used traditional medicine at least once in their lifetime and 45 (46.39%) patients used traditional medicine and modern medicine concomitantly. Participants’ residence (adjusted odds ratio = 2.79, confidence interval = 1.01–7.74, p-value = 0.049) and educational status (adjusted odds ratio = 1.76, confidence interval = 1.61–5.09, p-value = 0.032) had significant association with attitude toward traditional medicine, while patients’ age (adjusted odds ratio = 1.43, confidence interval = 1.32–4.96, p-value = 0.039), residence (adjusted odds ratio = 2.18, confidence interval = 1.10–4.32, p-value = 0.025), and occupation (adjusted odds ratio = 3.38, confidence interval = 1.55–7.38, p-value = 0.002) had significant association with their traditional medicine use. Conclusion: Half of the study participants had good attitude toward traditional medicine, and nearly, one-fourth of the participants had practiced traditional medicine along with modern medicine. Health service providers should be aware of traditional medicine use and advise patients on the dosing of traditional medicine.