bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation of a pan-European ecosystem and an interoperable platform for Smart and Healthy Ageing in Europe: An Innovation Action research protocol
Authors: Seidel Katja , Labor Melanie , Lombard-Vance Richard , McEvoy Emma , Cooke Michael , D’Arino Lucia , Desmond Deirdre , Ferri Delia , Franke Philip , Gheno Ilenia , Grigoleit Sonja , Guerra Barbara , Krukowski Artur , Pešoutová Marketa , Pietri Ilia , Prendergast David , Maguire Rebecca , Manso Marco , Saris A. Jamie , Sarlio-Siintola Sari , Silva Tatiana , Zarogianni Eleni , MacLachlan Malcom ,   SHAPES Consortium
Published: July 2022

As life expectancy continues to increase in most EU Member States, smart technologies can help enable older people to continue living at home, despite the challenges accompanying the ageing process. The Innovation Action (IA) SHAPES ‘Smart and Healthy Ageing through People Engaging in Supportive Systems’ funded by the EU under the Horizon 2020 Research and Innovation Programme (grant agreement number 857159) attends to these topics to support active and healthy ageing and the wellbeing of older adults.This protocol article outlines the SHAPES project’s objectives and aims, methods, structure, and expected outcomes. SHAPES seeks to build, pilot, and deploy a large-scale, EU-standardised interoperable, and scalable open platform. The platform will facilitate the integration of a broad range of technological, organisational, clinical, educational, and social solutions. SHAPES emphasises that the home is much more than a house-space; it entails a sense of belonging, a place and a purpose in the community. SHAPES creates an ecosystem – a network of relevant users and stakeholders – who will work together to scale-up smart solutions. Furthermore, SHAPES will create a marketplace seeking to connect demand and supply across the home, health and care services. Finally, SHAPES will produce a set of recommendations to support key stakeholders seeking to integrate smart technologies in their care systems to mediate care delivery.Throughout, SHAPES adopts a multidisciplinary research approach to establish an empirical basis to guide the development of the platform. This includes long-term ethnographic research and a large-scale pan-European campaign to pilot the platform and its digital solutions within the context of seven distinct pilot themes. The project will thereby address the challenges of ageing societies in Europe and facilitate the integration of community-based health and social care. SHAPES will thus be a key driver for the transformation of healthcare and social care services across Europe.
Higher Education and Athlete’s Second Career
Authors: Metelski Adam 
Published: July 2022

Introduction and purpose. Many athletes obtain popularity during their time in sports, but what they do after the end of their professional careers is something that is rarely well known. It has to be stated that a sports career is a specific activity because it starts early in life, lasts relatively short, and the greatest successes usually occur when non-athlete peers are just starting to climb the steps of a typical professional career. Some former athletes do great after they retire from sports, but there are also many of those who have difficulties finding themselves in a new for them reality. The article aims to present how the level of education of former athletes’ affects their subsequent professional careers.
Material and method. The study involved 301 former basketball players who previously played in 4 top leagues in Poland. The dependent variables in this study are the most common in the literature on the subject indicators of career success, such as earnings and job satisfaction. In turn, the independent variable is the level of education. In addition, the study considered whether the represented sports level influences the acquisition of education.
Results. It turns out that those players who played in the top league finished their sports careers later and thus earned longer on basketball. However, more players from the lower leagues have higher education, and they are now more satisfied with their work.

Conclusions. It may not be easy to combine professional sports at the highest level with studying. But the results of the research show that in the case of basketball, many athletes graduate from university. What is more, former players with higher education are usually very satisfied with their current job. In conclusion, it can be stated that former basketball players do well in their second careers, compared to the national average.
SITUAÇÃO REGULATÓRIA ATUAL E PROPOSTA DE UTILIZAÇÃO DA ESPECTROSCOPIA RAMAN COMO TÉCNICA DE MONITORAMENTO DA UNIFORMIDADE DE CONTEÚDO NA PARTIÇÃO DE COMPRIMIDOS SULCADOS
Authors: Ribeiro Vanessa Gonçalves de Magalhães , Bandini Thiago Bousquet , Rocha Helvécio Vinícius Antunes 
Published: July 2022

Dentre as formas farmacêuticas existentes, as mais utilizadas são as sólidas, mais especificamente os comprimidos. Estes podem apresentar um sulco em sua superfície de forma a viabilizar sua partição, uma prática comum, principalmente no tratamento de crianças e idosos. Pesquisas revelam que a divisão de comprimidos e o método de partição podem interferir na dosagem do fármaco e prejudicar o regime terapêutico. Algumas bases regulatórias e farmacopeias reconhecem a prática da partição e requerem a realização de testes para avaliação da uniformidade de unidade de dose em comprimidos sulcados. Assim, esse trabalho propõe avaliar o impacto da partição de comprimidos sulcados utilizando os ensaios propostos nas principais farmacopeias e apresentando o Raman como técnica alternativa. Dessa forma, foi realizada uma revisão bibliográfica narrativa utilizando diferentes bases de dados e agências regulatórias. Algumas bases regulatórias permitem a partição de comprimidos com recomendações e as farmacopeias preconizam que esta seja avaliada através do ensaio de uniformidade de unidade de dose. Estudos demonstraram que a divisão utilizando cortadores de comprimidos é mais precisa, seguida pelo corte manual e, por fim, usando faca e tesoura. A técnica Raman pode ser utilizada para a avaliação proposta. Diante da carência desse tema, percebe-se a necessidade de regulamentação mais detalhada. Alguns estudos informam que é necessário que o comprimido apresente algumas características para que a partição ocorra uniformemente e Raman demonstrou rapidez na caracterização de substâncias e comparabilidade de resultados frente a outras técnicas.
ACTIVE FOOD PACKAGING: A BRIEF REVIEW OF BIODEGRADABLE FILMS, EDIBLE COATINGS, AND SACHETS
Authors: Da Silveira Michelle Fernandes , Rabanal Raúl Comettant 
Published: July 2022

Food packaging generally consists of low-cost and non-degradable plastic materials that contribute to environmental pollution. For this reason, new food-packaging systems with good mechanical and barrier properties have been developed as an alternative to replace synthetic polymers used in food packaging. In this sense, this article briefly reviews the active packaging concept and the development of biodegradable films, edible coatings, and sachets used in food preservation. These technological innovations gained increasing importance in the food industry over the years, constituting a new paradigm in the industry, as they interact desirably with food, promoting various solutions such as: extending or maintaining the shelf life, monitoring or improving the quality and safety of food products. In addition, these innovative systems have aroused the interest of researchers for their ability to prevent deterioration and maintain the fresh aspect, firmness, and brightness of foods, making them more attractive to consumers. Several studies have shown that active packaging is an efficient system for preserving fruits and vegetables. The application of biodegradable films, edible coatings, and sachets was discussed in this work, showing the benefits of their use in various food products.
Polyvinyl alcohol/gum Arabic hydrogel preparation and cytotoxicity for wound healing improvement
Authors: Elblbesy Mohamed A. , Hanafy Taha A. , Shawki Mamdouh M. 
Published: July 2022

Abstract
The application of pure polyvinyl alcohol (PVA) hydrogel as wound dressing faces many restrictions due to its insufficient elasticity, stiff membrane, and very limited hydrophilicity. These drawbacks can be limited through cross-linking with other natural biopolymers such as gum Arabic (GA). PVA hydrogels blended with six different GA concentrations were prepared. The characterization of these hydrogels was performed by Fourier transform infrared spectrophotometer, X-ray diffraction, and scanning electron microscope. The swelling ratio (% SR) percentage has been calculated. The possible cytotoxicity was determined using a sulforhodamine B assay. Wound healing test was performed on human skin fibroblast cells. Our results indicated that by increasing GA concentration in PVA hydrogel, the % SR increases and the cytotoxicity effect decreases. The results indicate also a significant gradual decrease in the wound area with time as the GA concentration increases in the PVA hydrogel. Therefore, GA improves the biological applications of PVA hydrogel.
An intelligent approach for reservoir quality evaluation in tight sandstone reservoir using gradient boosting decision tree algorithm
Authors: Ma Longfei , Xiao Hanmin , Tao Jingwei , Zheng Taiyi , Zhang Haiqin 
Published: July 2022

Abstract
This article focuses on the study of identifying the quality of tight sandstone reservoirs based on machine learning. The machine learning method – Gradient Boosting Decision Tree (GBDT) algorithm is used to design and classify reservoir quality. First, it is based on logging data, core observation, cast thin section, and reservoir physical statistics. The permeability, porosity, resistivity, mud content, sand-to-ground ratio, and sand thickness were preferred as reservoir evaluation criteria in the area, and the gray correlation method was used to obtain reservoir quality categories and construct training datasets. The machine learning GBDT algorithm is used to train and test the obtained dataset. It is found that the recognition accuracy of the GBDT model is 95% by confusion matrix analysis. In addition, it is compared with four commonly used reservoir prediction methods (Bayesian discriminant method, random forest, support vector machine, and artificial neural network) for verifying the reliability of the GBDT model. Finally, the GBDT model is used to identify the reservoir quality of the study area, and it is well verified in the production data. The research results show that the GBDT model can become an important tool for rapid and real-time tight sandstone reservoir evaluation.
Adsorption capacity of bio-char prepared from the pyrolysis of hazelnut shells at different temperatures
Authors: Zhao Chenxi , Zhang Yu , Xing Yupeng , Yang Yulong , Gong Ao , Lv Yuanyuan , Zhang Yuhan , Chen Aihui , Liu Xiaogang , Chen Juhui 
Published: July 2022

Abstract
Biomass pyrolysis to produce bio-char is one of the scientific and effective means of utilizing biomass resources. Differ from previous studies, this paper explored the effect of pyrolysis temperature (400–1000 °C) on the adsorption capacity of hazelnut shell bio-char from two perspectives, including physical macroscopic structure and functional group microscopic adsorption, and the practical adsorption application tests on common 7 kinds of heavy metals in polluted water were further carried out. The results showed that the yield and adsorption of bio-char prepared at different pyrolysis temperatures varied significantly, as the temperature increased, bio-char yield and surface acid functional group content decreased, the adsorption rate on most of heavy metals increased firstly and then decreased (except for Cr6+), the adsorption capacity of bio-char prepared at above 600 °C was mainly affected by physical macroscopic structure, and at 800 °C, bio-char had a large number of pore structures, and pore structure has been fully developed, iodine adsorption value and BET specific surface area were 595.36 mg/g and 197.32 mg/m2, respectively, the adsorption effect of bio-char on Cr6+, Cd2+, Zn2+, Cu2+ and Ni2+ were best, and the adsorption rates were 45.23%, 44.14%, 60.11%, 61.28% and 65.07% respectively. It revealed that although the absorption effect of bio-chars prepared at different temperatures on different heavy metals had a great variation, large specific surface area and developed pore structure still played important role in the adsorption capacity of bio-char. These provided a reference for the application of hazelnut shell bio-char based on adsorption properties, especially absorbing heavy metals in polluted water.
The crystal structure of 3-(2-bromophenyl)-1,5-di-p-tolylpentane-1,5-dione, C25H23BrO2
Authors: Liu Wanxing , Dai Yifan , Shen Guodong 
Published: July 2022

Abstract
C25H23BrO2, monoclinic, P21/c (no. 14), a = 9.6229(7) Å, b = 21.7953(16) Å, c = 10.9104(6) Å, β = 109.330(7)°, V = 2159.3(3) Å3, Z = 4, R

gt
(F) = 0.0499, wR

ref
(F
2) = 0.1385, T = 293 K.
The metabolic phenotype of patients with primary aldosteronism: impact of subtype and sex – a multicenter-study of 3566 Caucasian and Asian subjects
Authors: Spyroglou Ariadni , Handgriff Laura , Müller Lisa , Schwarzlmüller Paul , Parasiliti-Caprino Mirko , Fuss Carmina Teresa , Remde Hana , Hirsch Anna , O’Toole Samuel Matthew , Thuzar Moe , Petramala Luigi , Letizia Claudio , Deflorenne Elisa , Amar Laurence , Vrckovnik Rok , Kocjan Tomaz , Zhang Catherine D , Li Dingfeng , Singh Sumitabh , Katabami Takuyuki , Yoneda Takashi , Murakami Masanori , Wada Norio , Inagaki Nobuya , Quinkler Marcus , Ghigo Ezio , Maccario Mauro , Stowasser Michael , Drake William M , Fassnacht Martin , Bancos Irina , Reincke Martin , Naruse Mitsuhide , Beuschlein Felix 
Published: July 2022

Background
Accumulating evidence suggests that primary aldosteronism (PA) is associated with several features of the metabolic syndrome, in particular with obesity, type 2 diabetes mellitus, and dyslipidemia. Whether these manifestations are primarily linked to aldosterone-producing adenoma (APA) or bilateral idiopathic hyperaldosteronism (IHA) remains unclear. The aim of the present study was to investigate differences in metabolic parameters between APA and IHA patients and to assess the impact of treatment on these clinical characteristics.

Methods
We conducted a retrospective multicenter study including 3566 patients with APA or IHA of Caucasian and Asian origin. We compared the prevalence of metabolic disorders between APA and IHA patients at the time of diagnosis and 1-year post-intervention, with special references to sex differences. Furthermore, correlations between metabolic parameters and plasma aldosterone, renin, or plasma cortisol levels after 1 mg dexamethasone (DST) were performed.

Results
As expected, APA patients were characterized by higher plasma aldosterone and lower serum potassium levels. Only female IHA patients demonstrated significantly worse metabolic parameters than age-matched female APA patients, which were associated with lower cortisol levels upon DST. One-year post-intervention, female adrenalectomized patients showed deterioration of their lipid profile, when compared to patients treated with mineralocorticoid receptor antagonists. Plasma aldosterone levels negatively correlated with the BMI only in APA patients.

Conclusions
Metabolic alterations appear more prominent in women with IHA. Although IHA patients have worse metabolic profiles, a correlation with cortisol autonomy is documented only in APAs, suggesting an uncoupling of cortisol action from metabolic traits in IHA patients.
The importance of MRI quality and reader’s experience for detecting an adenoma in Cushing’s disease
Authors: Nasi-Kordhishti Isabella , Grimm Florian , Giese Sabrina , Lörincz Katalin Nóra , Bender Benjamin , Honegger Jürgen 
Published: July 2022

Objective
In Cushing’s disease (CD), detection of an adenoma by MRI is challenging. The aim of this study is to compare real-life MRI in the initial diagnostic workup of CD with high-quality MRI performed in a tertiary center for pituitary diseases.

Design and methods
We retrospectively analyzed 139 patients with CD who underwent primary transsphenoidal surgery (TSS) in our department and had both an MRI conducted at a different institution (external MRI; extMRI) and an MRI conducted at our institution (internal MRI; intMRI). Preoperative interpretation of MRI was performed independently by an external radiologist (extRAD), an internal neuroradiologist (intRAD) and a pituitary surgeon (SURG). Intraoperative detection of an adenoma and endocrinological remission provided proof of the true adenoma localization in 105 patients.

Results
Interpretation of extMRI by extRAD and SURG was concordant in only 64% (89/139) of cases, while 74.1% (103/139) concordance was observed for interpretation of intMRI by intRAD and SURG. Based on extMRI, the true localization of the adenoma was correctly predicted in only 46.7% of the patients by extRAD and in 65.7% by SURG. In contrast, the sensitivity to correctly identify the adenoma on intMRI was 80.0% for intRAD and 94.3% for SURG.

Conclusion
Both the quality of MRI and the reader’s experience are paramount for detection of microadenomas in CD. Every effort should be made to perform high-quality initial MRI according to current standards and to ensure rating by an expert in pituitary imaging.
Functional and radiological outcome of autologous platelet rich plasma in chronic plantar fasciitis: A prospective study
Authors: Parikh Dharav Shekhar , Kumar R. Surendher , D Rajarajan , Kumar G Prasanna 
Published: July 2022

Plantar fasciitis is one of the most common causes of foot pain. It results from sustained stress of weight bearing - hopping, jumping, running -which results in micro trauma to plantar fascia which further leads to plantar fasciitis. It constitutes 11% to 15% of all foot symptoms. Its prevalence is 8% to 10% in general population. It commonly affects at the age of 40 to 60 years. Recently platelet rich plasma was used in treating in degeneration, muscle and tendon injuries. Hence, the present study aimed to assess the treatment outcome of autologous platelet rich plasma injection in treatment of plantar fasciitis. In this prospective study, we enrolled 35 patients with plantar fasciitis coming to OPD or casualty. Patients satisfying inclusion criteria were selected based on consecutive sampling. 11 patients responded well to conservative management and 3 patients had loss of follow up. The different scoring systems were adopted such as VAS and AOFAS for pain assessment. The thickness of plantar fascia was determined by ultrasound technique. Autologous platelet rich plasma was prepared and the same was injected. The outcome analysis was done at 2 weeks, 3 months, and 6 months; and compared with pre injection values. From pre-injection to up to post-6 months period, the VAS reduction was statistically significant (P&#60;0.0001). All the time interval, the AOFAS was increased which was statistically significant (P&#60;0.001). The injection was effective in reducing the thickness of plantar fascia, which was found to be statistically significant at all the time intervals (P&#60;0.001). Autologous PRP injection for chronic plantar fasciitis was found to be an effective treatment modality for chronic plantar fasciitis.
Arthritis with osteoporosis crippled the elderly during Covid-19 pandemic: A silent killer?
Authors: Govil Gaurav , Tomar Lavindra , Dhawan Pawan 
Published: July 2022

The COVID-19 pandemic impacted the elderly both directly by the affection due to infection and indirectly by the aggravation of the pre-existing medical comorbidities. The management of the chronic diseases took a relative back-seat for an active treatment protocol strategy. The clinicians emphasised on the conservative measures to manage arthritis and osteoporosis. The delayed assessment had a profound negative impact with significant progression of arthritis and osteoporosis amongst the elderly. The crippling effect of COVID-19 pandemic in the elderly presented furthermore with the advanced stages of arthritis and worsened osteoporosis for the management. The delay in timely offer of surgery for the arthritic joint compromised the functional outcomes. There has been a silent worsening with increased morbidity and mortality.The literature review and guidelines formulated emphasized on the timely remedial measures either surgical or conservative for the management of arthritis and osteoporosis in an elderly to halt the silent progression, allow a healthy lifestyle with an improved quality of life. The elderly should have priority for an individualized management strategy even during the pandemic to reduce this “silent” morbidity and mortality.
Pengembangan latihan imagery untuk meningkatkan lay up shoot bola basket di klub hutama manggala malang
Authors: Amin Zakiy Zainul , Rahayuni Kurniati , Taufik Taufik 
Published: July 2022

Tujuan dari penelitian ini adalah untuk pengembangan latihan imagery untuk meningkatkan lay up shoot bola basket di klub bola basket Hutama Manggala Kota Malang. Pengembangan ini menggunakan metode Research and Development (R&D) model Borg & Gall menggunakan 9 langkah. Produk divalidasi oleh 3 ahli, dengan: (1) ahli psikologi, (2) ahli bola basket, dan (3) ahli media. Penilaian validator menunjukkan hasil dari ahli media sebesar 75% (cukup valid), ahli psikologi sebesar 89,29% (sangat valid), ahli bola basket sebesar 64,29% (cukup valid). Produk media diuji coba terhadap kelompok kecil sebanyak 1 pelatih dan 4 atlet dipilih dengan acak berdasarkan kemampuan. Dalam uji coba kelompok besar sebanyak 1 pelatih dan 14 atlet. Didapatkan hasil dari uji kecil 98% (sangat valid) serta uji kelompok besar 97% (sangat valid). Berdasarkan hasil uji kelompok kecil dan besar produk video dinyatakan layak untuk digunakan.
Landslide Susceptibility Mapping along the Anninghe Fault Zone in China using SVM and ACO-PSO-SVM Models
Authors: Chen Zhuo , Zhou Hongfu , Ye Fei , Liu Bin , Fu Wenxi 
Published: July 2022

Abstract
In the present study, a hybrid machine learning model was designed by integrating ant colony optimization (ACO), particle swarm optimization (PSO), and support vector machine (SVM) algorithms. The model was used to map the landslide susceptibility of the Anninghe fault zone in Sichuan Province, China. Based on this, 12 conditioning factors associated with landslides were considered, namely, altitude, slope angle, cutting depth, slope aspect, relief amplitude, stream power index (SPI), gully density, lithology, rainfall, road density, distance to fault, and peak ground acceleration (PGA). The overall performance of the two resulting models was tested using the receiver operating characteristic (ROC), area under the ROC curve (AUC), Cohen’s kappa coefficient, and five statistical evaluation measures. The success rates of the ACO-PSO-SVM model and the SVM model were 0.898 and 0.814, respectively, while the prediction rates of the two models were 0.887 and 0.804, respectively. The results show that the ACO-PSO-SVM model yields better overall performance and accurate results than the SVM model. Therefore, in conclusion, the ACO-PSO-SVM model can be applied as a new promising method for landslide susceptibility mapping in subsequent studies. The results of this study will be useful for land-use planning, hazard prevention, and risk management.