bluuebunny/crossref_metadata_2025_split huggingface dataset:
liderazgo transformacional y su incidencia en los recursos tecnológicos educativos que se aplican en el área de inglés de la Unidad Educativa Liceo Cristiano de Guayaquil.
Authors: Jiménez-Plaza Xavier , Uday-Guerrero María , Escobar-Bermeo Eleana , Prieto-López Yeimer 
Published: February 2022

Resumen
Los desafíos y cambios en el entorno educativo actual hacen del liderazgo una prioridad máxima para las instituciones educativas y los docentes. El presente artículo científico investigativo ofrece los resultados de un estudio sobre un nuevo liderazgo
transformacional en el uso de los recursos tecnológicos educativos que aplicarán los docentes en el área de inglés de la Unidad Educativa Liceo Cristiano de Guayaquil. Como objetivo se propone la ejecución de un plan de capacitación, que sirva para que los docentes especialmente en el área de inglés, enfrenten nuevos desafíos en el uso de los recursos tecnológicos para mejorar y efectivizar el proceso de enseñanza y aprendizaje. En efecto, la investigación es de diseño no experimental y exploratorio bajo un enfoque mixto. La aplicación de los métodos científicos como el de sistematización teórica y el histórico lógico; y como método empírico el de medición, nos ayudará a la búsqueda de información, cuyos resultados sean describibles, medibles y verificables en la investigación, la población y muestra está constituida por 10 docentes del área de inglés, como objeto de estudio. Para la recolección de datos de las variables, se aplicó la técnica de la entrevista virtual, con un cuestionario de respuestas múltiples opciones, con la escala de tipo Likert. El tratamiento estadístico utilizado en una matriz de Excel generada por la herramienta Google Forms. También se realizó la entrevista de expertos a directivos, jefes, coordinadores de área y docentes de experiencia. Los resultados se analizaron en el nivel descriptivo-explicativo con enfoque mixto, cualitativo y cuantitativo para las variables en estudio. Los resultados permitieron sistematizar las conclusiones, recomendaciones y propuesta. Con el aporte de este artículo de investigación las instituciones educativas tienen un referente para promover cambios hacia un nuevo liderazgo transformacional en el uso de nuevos recursos tecnológicos en mejorar la calidad educativa.
Modelo teórico para la estimulación de la inteligencia emocional como eje transversal en la gestión educativa.
Authors: Arias-Pareja Amparo , Puma-Solis Mariuxi 
Published: February 2022

El presente artículo de investigación bibliográfica tiene como objetivo aportar un modelo teórico direccionado al desarrollo de la inteligencia emocional para lograr un adecuado liderazgo de los directivos y los docentes en las instituciones educativas del sector norte de la ciudad de Guayaquil - Parroquia Pascuales. El enfoque de esta investigación es mixto y se utilizaron métodos teóricos como: el histórico-lógico y el de sistematización teórica para establecer el estado del arte, facilitar el análisis y la clasificación de las fuentes de información, para analizar los antecedentes y la importancia de la inteligencia emocional en el ámbito educativo. Se emplearon métodos empíricos tales como la observación y las encuestas dirigidas a directivos y docentes en temas de gerencia educativa, para determinar la importancia de la inteligencia emocional como eje transversal en el liderazgo educativo. Así mismo, se aplicó el método de criterio de expertos para validar la propuesta de investigación. Una de las principales conclusiones que se han obtenido de este estudio es el control de las emociones y los sentimientos, conocerse y automotivarse generando resultados favorables en el ámbito laboral y fomentando el compromiso entre los integrantes de la comunidad educativa.
Efeitos da extração hidroetanolica e sequencial sobre o potencial tóxico dos extratos de diferentes partes da Parkia platycephala do Cerrado tocantinense
Authors: Fernandes Rachel de Moura Nunes , Dias Tais Souza dos Santos , Silva Marcelo Henrique Toscano da , Scapin Elisandra 
Published: February 2022

Comumente percebe-se o uso de plantas como medicamentos fitoterápicos, entretanto, a linha tênue entre o tratamento e a intoxicação é uma realidade. Este estudo avaliou a toxicidade dos extratos da folha, casca, flor e semente da Parkia platycephala através do crescimento radicular da Allium cepa. Foram realizadas duas metodologias de extração, uma polar e uma sequencial, ambas usando aparato Soxhlet, obtendo-se extratos brutos (FEB, CEB, FREB, SEB), metanolicos (FEM, CEB, FREM, SEM) e etanolicos (FEE, CEE, FREE, SEE) da folha, casca, flor e semente, respectivamente. O potencial tóxico de cada extrato foi avaliado em três concentrações (50, 250, 750 µg/ml), tendo a água mineral como controle negativo. Observou-se que das 36 amostras analisadas, 25% estimularam o crescimento radicular da A. cepa nas condições avaliadas e 39% mantiveram as características de crescimento do controle negativo, indicando não toxicidade desses extratos. Os melhores índices de crescimento radicular foram obtidos na casca (2,7) e flor (2,0) pela metodologia sequencial. O extrato bruto da casca (CEB) não apresentou toxicidade nas concentrações avaliadas. Os extratos da semente, da extração sequencial, apresentaram toxicidade a partir da concentração 250 µg/ml. Na concentração de 750 µg/ml, apenas um extrato não apresentou toxicidade. Diante dos resultados apresentados, acredita-se no potencial uso terapêutico da espécie P. platycephala nas concentrações inferiores a 250 µg/ml, no entanto é necessário estudos mais detalhados para confirmação da toxicidade dos extratos da espécie.
Transtornos neurocognitivos e demência relacionados ao HIV em pessoas que fazem uso de antirretroviral: uma revisão integrativa
Authors: Silva Roni Robson da , Silva Leandro Andrade da , Silva Maria Virginia Godoy da , Araujo Michael Silva , Neves Milena Preissler das , Souza Marcus Vinicius Lessa de , Oliveira Elson Santos de , Silva Junior Milton Domingues da , Ribeiro Mônica Barreto 
Published: February 2022

Distúrbios neurológicos e comprometimento cognitivo são comumente associados ao HIV. Embora o comprometimento neurocognitivo grave e progressivo tenha se tornado raro em clínicas de infectologia na era da terapia antirretroviral TARV potente, a maioria das PVHIV em todo o mundo apresenta desempenho abaixo das expectativas em testes neurocognitivos formais. Objetivo: Evidenciar os efeitos do HIV associado ao comprometimento neurocognitivo. Método: Trata-se de uma revisão integrativa da literatura que seguiu a estratégia PICO para identificar os fatores associados ao Transtorno Neurocognitivo relacionados ao HIV. A busca dos artigos foi realizada em três bases de dados eletrônicas: Medline, Lilacs e Scielo. Foram utilizados os descritores “Complexo AIDS Demência”, “HIV”, “Sobreviventes de Longo Prazo ao HIV”, “Demência”, “Transtornos Neurocognitivos”, com textos completos, publicados no período de 2012 a 2022, no idioma inglês, português e espanhol e foi usado o operador booleano AND. Resultado: Foram encontrados 356 artigos. Vinte e cinco artigos foram selecionados para serem lidos na íntegra e 5 atenderam aos critérios desta revisão. Conclusão: As comorbidades contribuem para o comprometimento, mas são insuficientes para explicar a frequência do comprometimento encontrado. Os marcadores de doença do HIV, como a carga viral atual e a contagem de CD4, não estão mais fortemente associados ao comprometimento contínuo da terapia, enquanto os marcadores de doença cardiovascular e os marcadores inflamatórios parecem mais associados. Novos biomarcadores de líquido cefalorraquidiano e neuroimagem são necessários para detectar e acompanhar o comprometimento. Pesquisa em andamento para otimizar a terapia do HIV no sistema nervoso central, e potencialmente intervir nos mecanismos de neurotoxicidade a jusante continuam sendo importantes avenidas de investigação futura. Em última análise, o controle total do vírus no cérebro é um passo necessário para a erradicação do HIV.
Psychophysiological Responses to Laughter Yoga in Women: Two Studies on the Visual and Practice Effects of this New Physical Activity
Authors: Szabo Attila , Berkes Tímea , Ihász Ferenc , Köteles Ferenc 
Published: February 2022

Laughter yoga is claimed to have similar psychological and physiological effects to exercising. The objectives of the two studies reported here were to examine the visual and practice effects of laughter yoga in women. Study 1 was performed with 13 young women (mean age =21.92 ± SD = 1.66 years) who only experienced laughter yoga visually. Study 2 investigated 25 older women (mean age = 63.83 ± SD = 11.91 years) during an in-situ laughter yoga class. There was no relationship between the humor styles, expectancy, and the magnitude of change in psychological measures, neither in visual nor in the practice experience of laughter yoga. In Study 1, negative affect decreased while feeling states, heart rate, and respiration rate increased because of watching laughter yoga. In Study 2, feeling states, felt arousal, positive affect, and negative affect improved after the class. Even more intriguingly, heart rate also increased, and the basic metabolic rate during the class was comparable to that of light to moderate physical activity. As laughter yoga is characterized by positive psychological and cardiometabolic changes, it could represent a pleasurable, healthy, and secure form of recreation for all, but based on the current results, especially for older women.
Keywords: affect, exercise, humor, recreation, social.
Pengaruh Air Kelapa (Cocos nucivera) dan Bokashi Kirinyuh (Chromolaena odorata) terhadap Pertumbuhan Tanaman Sawi (Brassica juncea L.)
Authors: Sumardin Sumardin , Arif Norma , Bahrun Andi 
Published: February 2022

Penelitian ini bertujuan untuk mengetahui pengaruh penyiraman air kelapa muda (Cocos nucivera)dan bokasi krinyuh (Chromolaenaodorata)terhadap pertumbuhan tanaman sawi(Brassica juncea L.).Penelitian ini disusun berdasarkan Rancangan Acak Kelompok (RAK) dalam pola faktorial yang terdiri dari 2 faktor.Faktor pertama adalah air kelapa muda yang terdiri atas 4 taraf: tanpa air kelapa (A0), air kelapa muda 100 ml polibag-1(A1), 150 ml polibag-1 (A2), 200 ml polibag-1 (A3). Faktor kedua adalah bokasi krinyuh yang terdiri atas 4 taraf yaitu tanpa bokasi krinyuh (K0), bokasi krinyuh 75 gram polibag-1 (K1), bokasi krinyuh 100 gram polibag-1 (K2), bokasi krinyuh 125 gram polibag-1 (K3).Hasil penelitian menunjukan bahwa interaksi antara air kelapa muda dan bokasi krinyuh tidak berpengaruh terhadap semua variabel yang diamati: mulai dari tinggi tanaman, jumlah daun, luas daun, berat segar tanaman, berat segar akar, berat kering tanaman, berat kering akar. Perlakuan air kelapa muda secara mandiri berpengaruh sangat nyata terhadap variabel yang diamati yakni tinggi tanaman pada 16 HST dan berpengaruh nyata pada 28 HST, jumlah daun 16 HST dan luas daun 16 HST.Pemberian bokasi krinyuh memberikan pengaruh sangat nyata terhadap semua variabel pertumbuhan tanaman sawi yakni tinggi tanaman 10, 16, 22, 28 HST, jumlah daun 10, 16, 22, 28 HST, luas daun 10, 16, 22, 28 HST, berat segar tanaman, berat segar akar, berat kering tanaman,dan berat kering akar.Kata Kunci: Air kelapa muda, bokasi, krinyuh dan tanaman sawi.
Advances in Mesenchymal Stem Cell-Derived Exosomes as Drug Delivery Vehicles
Authors: Rao Dingyu , Huang Defa , Sang Chengpeng , Zhong Tianyu , Zhang Zuxiong , Tang Zhixian 
Published: February 2022

Exosomes are tiny vesicles with a double membrane structure that cells produce. They range in diameter from 40 to 150 nm and may contain a variety of biomolecules including proteins and nucleic acids. Exosomes have low toxicity, low immunogenicity, and the ability to encapsulate a wide variety of substances, making them attractive drug delivery vehicles. MSCs secrete large amounts of exosomes and hence serve as an excellent source of exosomes. MSCs-derived exosomes have regenerative and tissue repair functions comparable to MSCs and can circumvent the risks of immune rejection and infection associated with MSC transplantation, indicating that they may be a viable alternative to MSCs’ biological functions. In this review, we summarized the drug delivery methods and advantages of exosomes, as well as the advancement of MSC exosomes as drug carriers. The challenges and prospects of using exosomes as drug delivery vectors are presented.
Mg-HA-C/C Composites Promote Osteogenic Differentiation and Repair Bone Defects Through Inhibiting miR-16
Authors: Qi Hong , Liu Yang , Wu Lu , Liu Chun , Ni Su , Liu Qizhan , Ni Xinye , Sun Qiang 
Published: February 2022

The hydroxyapatite (HA) coating on carbon/carbon (C/C) is reasonable and feasible to obtain bone graft materials with appropriate mechanical and biological properties. However, improvement of the physical and chemical properties of HA-C/C composites to promote bone regeneration and healing remains a challenge. In our present study, the HA coatings on C/C with magnesium (Mg) (Mg-HA-C/C) composites were synthesized that Ca (NO3)2, Mg (NO3)2, and NH4H2PO4 were mixed and coatings were made by electromagnetic induction deposition’s heating. As determined with in vitro experiments, Mg-HA-C/C composites containing 10 and 20% Mg decreased miR-16 levels, increased cell viability, elevated the levels of osteogenesis-related genes, and promoted osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs) seeded on their surfaces. In a rat model of skull defects, compared to the control group, at 4 and 12 weeks after the operation, the bone volume fraction (BV/TV) of Mg-HA-C/C composite group was increased by 8.439 ± 2.681% and 23.837 ± 7.845%, as well as the trabecular thickness (Tb.Th) was 56.247 ± 24.238 μm and 114.911 ± 34.015 μm more. These composites also increased the levels of ALP and RUNX2 in skull. The Mg-HA-C/C composite-enhanced bone regeneration and healing were blocked by in situ injection of an miR-16 mimic lentivirus vector. Thus, Mg-HA-C/C composites promote osteogenic differentiation and repair bone defects through inhibiting miR-16.
Smartwatch Electrocardiograms for Automated and Manual Diagnosis of Atrial Fibrillation: A Comparative Analysis of Three Models
Authors: Abu-Alrub Saer , Strik Marc , Ramirez F. Daniel , Moussaoui Nadir , Racine Hugo Pierre , Marchand Hugo , Buliard Samuel , Haïssaguerre Michel , Ploux Sylvain , Bordachar Pierre 
Published: February 2022

AimsThe diagnostic accuracy of proprietary smartwatch algorithms and the interpretability of smartwatch ECG tracings may differ between available models. We compared the diagnostic potential for detecting atrial fibrillation (AF) of three commercially available smartwatches.MethodsWe performed a prospective, non-randomized, and adjudicator-blinded clinical study of 100 patients in AF and 100 patients in sinus rhythm, patients with atrial flutter were excluded. All patients underwent 4 ECG recordings: a conventional 12-lead ECG, Apple Watch Series 5®, Samsung Galaxy Watch Active 3®, and Withings Move ECG® in random order. All smartwatch ECGs were analyzed using their respective automated proprietary software and by clinical experts who also graded the quality of the tracings.ResultsThe accuracy of automated AF diagnoses by Apple and Samsung outperformed that of Withings, which was attributable to a higher proportion of inconclusive ECGs with the latter (sensitivity/specificity: 87%/86% and 88%/81% vs. 78%/80%, respectively, p &lt; 0.05). Expert interpretation was more accurate for Withings and Apple than for Samsung (sensitivity/specificity: 96%/86% and 94%/84% vs. 86%/76%, p &lt; 0.05), driven by the high proportion of uninterpretable tracings with the latter (2 and 4% vs. 15%, p &lt; 0.05).ConclusionDiagnosing AF is possible using various smartwatch models. However, the diagnostic accuracy of their automated interpretations varies between models as does the quality of ECG tracings recorded for manual interpretation.
The Role of Carbon Dioxide in the Rat Acute Stroke Penumbra
Authors: Yeo Leonard L. , Arnberg Fabian , Chireh Arvin , Sharma Vijay , Tan Benjamin , Gontu Vamsi , Little Philip , Holmin Staffan 
Published: February 2022

PurposeThe vasodilatory response to inhaled CO2 occurs in the acute stroke ischemic penumbra and may be a potential therapeutic modality.MethodsTwenty-two Sprague-Dawley rats were subjected to 90-min occlusion of the M2 segment of the middle cerebral artery (M2CAO) by endovascular technique. The animals were administered different C02 concentrations and scanned serially with 9.4 T MRI. Infarct tissue was determined by diffusion-weighted imaging (DWI) and hypoperfused tissue was determined by arterial spin labeling (PWI).Results4 animals were administered room air (RA)+ 6% CO2 (group 1), 6 animals RA+12% CO2 (Group 2) and 4 animals only RA (group 3). In the rats with CO2 administered (groups 1 and 2), the DWI lesion to cerebral hypoperfusion volume ratio (SD) at pre-CO2 administration, was 0.145(0.168), which increased to 0.708(0.731) during CO2 administration and reduced to 0.533(0.527) post-CO2 administration. In 9 of 10 rats the hypoperfused volume decreased when CO2 was administered. When CO2 was stopped the hypoperfused volume became larger again. Administration of RA+12% CO2 (Group 2) decreased the volume of CBF hypoperfusion significantly compared to the control group (95%CI: 0.084 ± 0.0213, p = 0.004).ConclusionInhaled CO2 appears to reduce the size of the hypoperfused tissue volume during acute stroke and may be a potential modality for treatment of acute ischemic stroke. These findings will nonetheless need to be validated in a larger cohort in other centers.
Identification of Favorable Zones of Gas Accumulation via Fault Distribution and Sedimentary Facies: Insights From Hangjinqi Area, Northern Ordos Basin
Authors: Anees Aqsa , Zhang Hucai , Ashraf Umar , Wang Ren , Liu Kai , Mangi Hassan Nasir , Jiang Ren , Zhang Xiaonan , Liu Qi , Tan Shucheng , Shi Wanzhong 
Published: February 2022

The Hangjinqi area was explored for natural gas around 40 years ago, but the efficient consideration in this area was started around a decade ago for pure gas exploration. Many wells have been drilled, yet the Hangjinqi area remains an exploration area, and the potential zones are still unclear. The Lower Shihezi Formation is a proven reservoir in the northern Ordos Basin. This study focuses on the second and third members of the Lower Shihezi Formation to understand the controlling factors of faults and sedimentary facies distribution, aimed to identify the favorable zones of gas accumulation within the Hangjinqi area. The research is conducted on a regional level by incorporating the 3D seismic grid of about 2500 km2, 62 well logs, and several cores using seismic stratigraphy, geological modeling, seismic attribute analysis, and well logging for the delineation of gas accumulation zones. The integrated results of structural maps, thickness maps, sand-ratio maps, and root mean square map showed that the northwestern region was uplifted compared to the southern part. The natural gas accumulated in southern zones was migrated through Porjianghaizi fault toward the northern region. Well J45 from the north zone and J77 from the south zone were chosen to compare the favorable zones of pure gas accumulation, proving that J45 lies in the pure gas zone compared to J77. Based on the faults and sedimentary facies distribution research, we suggest that the favorable zones of gas accumulation lie toward the northern region within the Hangjinqi area.
Geochemical Characteristics of Helium in Natural Gas From the Daniudi Gas Field, Ordos Basin, Central China
Authors: Liu Quanyou , Wu Xiaoqi , Jia Huichong , Ni Chunhua , Zhu Jianhui , Miao Jiujun , Zhu Dongya , Meng Qingqiang , Peng Weilong , Xu Huiyuan 
Published: February 2022

Helium-bearing gas is accumulated in the Lower Ordovician, Upper Carboniferous, and Lower Permian reservoirs of the Daniudi gas field in Ordos Basin, and the helium concentrations and isotopic compositions are investigated in order to reveal the abundance and origin of helium. Geochemical characteristics indicate that the natural gas from the Daniudi gas field has helium concentrations of 0.0271–0.1273%, with R/Ra ratios of 0.007–0.072. The 4He/20Ne ratios range from 848 to 17,000, which are substantially higher than the ratio of air or air saturated water. The proved helium reserves of the Daniudi gas field exceed 100 × 106 m3, suggesting an extra-large helium gas field. Helium in the field is of crustal origin and derived from the radioactive decay of U and Th in the rocks and minerals, with no significant contribution by atmospheric or mantle-derived helium. The natural gas in the Daniudi gas field displays the characteristics of typical crustal helium, which is consistent with the gases from cratonic basins (Ordos, Sichuan, and Tarim) in China, whereas the gases from rift basins (Songliao, Bohai Bay, and Subei) have experienced a significant addition of mantle-derived helium.
Synoptic and Climatic Conditions of an Extreme Snowstorm Event Over Northeast China and Its Climate Predictability
Authors: Wang Lushan , Fan Ke 
Published: February 2022

A blizzard struck Northeast China in November 2020, and the maximum daily snowfall broke its record since 1961. The synoptic and climatic conditions and the predictability of this extreme snowstorm event are examined by using the daily National Centers for Environmental Prediction (NCEP) reanalysis and the second version of the NCEP Climate Forecast System (CFSv2). The results show that an anomalous anticyclone over Japan and an anomalous cyclone in South China supplied abundant moisture and the rapidly enhanced Siberian high triggered the snowstorm. Before the snowstorm, the positive North Pacific Oscillation (NPO) and North Atlantic Oscillation (NAO) were essential for the accumulated water vapor. In addition, we find that the monthly NPO index and NAO index in November 2020 are both extremely strong compared to 1979–2019, and their combination converges to create the extreme snowstorm-related atmospheric circulation. The positive NPO and NAO together induce an anomalous anticyclone in Japan, which provides southerly water vapor transport to Northeast China. The midlatitude North Pacific warm sea surface temperature (SST) contributes to the positive NPO, and the Atlantic SST anomalies impact the positive NAO. However, the La Niña condition in 2020 might not be a key factor influencing the snowstorm. Finally, the subseasonal–seasonal skillful prediction of the snowfall can be made up to 3 days in advance. The CFSv2 had limited skill in forecasting the snowfall, NAO and NPO in November 2020. Improved predictability of extreme snowfall events is still needed.