bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tetraplegia is associated with increased hypoxic ventilatory response during nonrapid eye movement sleep
Authors: Vaughan Sarah , Sankari Abdulghani , Carroll Sean , Eshraghi Mehdi , Obiakor Harold , Yarandi Hossein , Chowdhuri Susmita , Salloum Anan , Badr M. Safwan 
Published: September 2022

AbstractPeople with cervical spinal cord injury (SCI) are likely to experience chronic intermittent hypoxia while sleeping. The physiological effects of intermittent hypoxia on the respiratory system during spontaneous sleep in individuals with chronic cervical SCI are unknown. We hypothesized that individuals with cervical SCI would demonstrate higher short‐ and long‐term ventilatory responses to acute intermittent hypoxia (AIH) exposure than individuals with thoracic SCI during sleep. Twenty participants (10 with cervical SCI [9 male] and 10 with thoracic SCI [6 male]) underwent an AIH and sham protocol during sleep. During the AIH protocol, each participant experienced 15 episodes of isocapnic hypoxia using mixed gases of 100% nitrogen (N2) and 40% carbon dioxide (CO2) to achieve an oxygen saturation of less than 90%. This was followed by two breaths of 100% oxygen (O2). Measurements were collected before, during, and 40 min after the AIH protocol to obtain ventilatory data. During the sham protocol, participants breathed room air for the same amount of time that elapsed during the AIH protocol and at approximately the same time of night. Hypoxic ventilatory response (HVR) during the AIH protocol was significantly higher in participants with cervical SCI than those with thoracic SCI. There was no significant difference in minute ventilation (V.E.), tidal volume (V.T.), or respiratory frequency (f) during the recovery period after AIH in cervical SCI compared to thoracic SCI groups. Individuals with cervical SCI demonstrated a significant short‐term increase in HVR compared to thoracic SCI. However, there was no evidence of ventilatory long‐term facilitation following AIH in either group.
Pattern of gonadotropin secretion along the estrous cycle of C57BL/6 female mice
Authors: Gusmao Daniela O. , Vieira Henrique R. , Mansano Naira S. , Tavares Mariana R. , de Sousa Ligia M. M. , Wasinski Frederick , Frazao Renata , Donato Jose 
Published: September 2022

AbstractThe pattern of gonadotropin secretion along the estrous cycle was elegantly described in rats. Less information exists about the pattern of gonadotropin secretion in gonad‐intact mice, particularly regarding the follicle‐stimulating hormone (FSH). Using serial blood collections from the tail‐tip of gonad‐intact C57BL/6 mice on the first day of cornification (transition from diestrus to estrus; hereafter called proestrus), we observed that the luteinizing hormone (LH) and FSH surge cannot be consistently detected since only one out of eight females (12%) showed increased LH levels. In contrast, a high percentage of mice (15 out of 21 animals; 71%) exhibited LH and FSH surges on the proestrus when a single serum sample was collected. Mice that exhibited LH and FSH surges on the proestrus showed c‐Fos expression in gonadotropin‐releasing hormone‐ (GnRH; 83.4% of co‐localization) and kisspeptin‐expressing neurons (42.3% of co‐localization) of the anteroventral periventricular nucleus (AVPV). Noteworthy, mice perfused on proestrus, but that failed to exhibit LH surge, showed a smaller, but significant expression of c‐Fos in GnRH (32.7%) and AVPVKisspeptin (14.0%) neurons. Finally, 96 serial blood samples were collected hourly in eight regular cycling C57BL/6 females to describe the pattern of LH and FSH secretion along the estrous cycle. Small elevations in LH and FSH levels were detected at the time expected for the LH surge. In summary, the present study improves our understanding of the pattern of gonadotropin secretion and the activation of central components of the hypothalamic–pituitary‐gonadal axis along the estrous cycle of C57BL/6 female mice.
Embolization of uterine artery pseudoaneurysm during pregnancy: case report and review of the literature
Authors: Metz Charlotte K. , Hinkson Larry , Gebauer Bernhard , Henrich Wolfgang 
Published: September 2022

Abstract

Objectives
Uterine artery pseudoaneurysm (UAP) is a rare but sinister complication during pregnancy. Diagnosis can be made by color Doppler ultrasound. Previous abdominal- and obstetric surgery increase the risk for UAP formation.

Case presentation
We present a case of a 36 year young healthy women, presenting at 27 weeks of gestation with acute lower abdominal pain. UAP was detected by color Doppler ultrasound. An endovascular coil embolization was performed, with good maternal and fetal outcome. Furthermore, a review of the literature looking at UAP embolization in pregnancy was performed.

Conclusions
UAP is reported to appear as a complication of endometriosis. UAP should be treated by endovascular coil embolization, which is a safe and with almost 100% success rate an effective treatment during pregnancy.
Prototypical associations in the production of words in English as a foreign language by L2 learners
Authors: Mora Jaqueline 
Published: September 2022

AbstractThis ongoing study attempts to explore the role semantic prototypes play in response to the production of words of a semantic category by two groups of learners differing in age and language level. Our main objectives point to i) the identification of the number of words produced in English regarding semantic prototypes by the groups of informants; ii) the analysis and comparison of the similarities and the differences of the prototypical associations provided by learners of different ages and different language levels; iii) the evidence of the universality of prototypes through the convergences and/ or divergences collected in the sample. The data collection instruments considered for this ongoing study are a background questionnaire and a productive semantic categorization task. Findings yielded that (i) there is evidence of prototype responses, and they are exclusively associated with the basic level of categorization; (ii) children retrieved fewer prototypical and non-prototypical words than adolescents in a lexical availability test; (iii) convergences and divergences are shown in the words retrieved by the two groups differing in age and language level. This study aims to evolve the dynamics of prototypical associations in language, and their linguistic, social, and cultural implications in communication when learning a foreign language.
Development of students’ spoken language in an online French course: Presentation of continuing doctoral research
Authors: Nerušilová Terezie 
Published: September 2022

Abstract
The present paper describes continuing doctoral research which examines the development of oral language during an online French course in terms of complexity, accuracy and fluency (CAF), and reflects on the possible influence of the online intervention on this development. The research is designed as a multiple-case study with 11 university students as participants of the research, each student forming a single case of the study. The pre-test post-test design was chosen in order to analyse students’ spoken performance before and after the intervention, and thus to assess its development. The paper outlines the results of accuracy analysis, which indicate that language performance cannot be judged solely by one aspect of CAF: many errors identified in this research seem to be a sign of the use of more complex language; and precise and accurate language without errors does not seem to be complex or fluent. The number of phonetic errors and some replies in the interviews suggest that the online course did not place enough importance on the teaching of pronunciation. These suppositions will be tested in the next stages of the research. The paper is part of the AILA Europe special issue.
How to use oral multimodal corpora and data-driven learning to teach French Talk-in-Interaction
Authors: Cousinard Clara 
Published: September 2022

Abstract
This paper presents one aspect of our ongoing research in the context of a doctoral thesis. We focus on the use of multimodal oral corpora to develop the interactional skills of learners of French as a foreign language (André 2018, Ravazzolo and Etienne 2019). To do so, we compiled a list of interactional difficulties through a survey of 20 researchers and French as a Foreign Language teachers. After that, we created a learner corpus to check whether the difficulties brought up in the survey were present in learners’ productions, and to narrow down our results. To better analyze this corpus, we conducted self-confrontations so that we could have input directly from the learners. The objective was to identify interactional difficulties that could be the object of data-driven learning (Johns 1991) sessions with intermediate-level learners of French as a Foreign Language. The paper is part of the AILA Europe special issue.
On the way to plant data commons – a genotyping use case
Authors: Feser Manuel , König Patrick , Fiebig Anne , Arend Daniel , Lange Matthias , Scholz Uwe 
Published: September 2022

Abstract
Over the last years it has been observed that the progress in data collection in life science has created increasing demand and opportunities for advanced bioinformatics. This includes data management as well as the individual data analysis and often covers the entire data life cycle. A variety of tools have been developed to store, share, or reuse the data produced in the different domains such as genotyping. Especially imputation, as a subfield of genotyping, requires good Research Data Management (RDM) strategies to enable use and re-use of genotypic data. To aim for sustainable software, it is necessary to develop tools and surrounding ecosystems, which are reusable and maintainable. Reusability in the context of streamlined tools can e.g. be achieved by standardizing the input and output of the different tools and adapting to open and broadly used file formats. By using such established file formats, the tools can also be connected with others, improving the overall interoperability of the software. Finally, it is important to build strong communities that maintain the tools by developing and contributing new features and maintenance updates. In this article, concepts for this will be presented for an imputation service.
Effect of micro and nano-sized ZrSiO4 particles on the friction and wear properties of polymer matrix composites
Authors: Sugözü Banu , Dağhan Behcet , Akdemir Ahmet , Sugözü İlker 
Published: September 2022

Abstract
In this study, the size effect of zircon (ZrSiO4) on the tribological characteristics of polymer matrix friction composites were investigated. Hence, four friction composites containing micro and nano-sized zircon particles (5 and 10 wt%) were developed and produced using powder metallurgy method. Their wear and friction characteristics were examined using a friction-wear test device. The weight loss and specific wear rate were measured and compared with that obtained for microsized zircon particles. The surfaces of samples were analyzed using a scanning electron microscope, and less wear was observed in the samples containing nano-sized zircon particles. The results revealed that the size of abrasive particles plays a key role in enhancing the friction coefficient and friction stability.
Thermomechanical evaluation of a glass-epoxy composite for astronomical optical devices
Authors: Cruz González Celso Eduardo , Torres Arellano Mauricio , Ledesma Ledesma Saúl , Alcántara Llanas Perla Itzel 
Published: September 2022

Abstract
Astronomical devices, such as optical benches, carry high precision instrumentation work at low temperatures (−150 °C). To fulfill engineering requirements, glass-epoxy composite trusses are proposed. To evaluate the performance of this solution, thermomechanical characterization is carried out by means of dynamic mechanical analysis (DMA), thermogravimetric analysis (TGA), flammability tests, and tensile test and Scanning Electron Microscopy (SEM) observations. Two family of coupons are tested; first one environmentally aged for 10 years and second one recently fabricated, both at 20, 0 and −20 °C. Ageing influence is more noticeable on thermal behavior as Tg and self-extinguish capacity are lower. Ultimate tensile strength and maximum strain are lower for the aged coupons (16–25%), but there is not a remarkable difference in terms of stiffness. Also, coupons mechanically tested at −20 °C show a slight increment in strength. These results show that ageing of glass-epoxy composites must be considered when high performance devices are conceived to be fabricated with.
Burying the Heros: Identifying the Archaeological Background of the Homeric Burial
Authors: Kourkoulakos Antonis 
Published: September 2022

Abstract
For centuries the Homeric epics, especially the Iliad, have fascinated and attracted the attention of the academic community and the wider public alike. Many scholars throughout the centuries endeavored to prove the historicity of the Iliad through the archaeological evidence. Though current academic research has long departed from those approaches, the epics contain important historical and cultural elements that were part of the reality not only of Homer’s contemporary (Iron Age) society but also, to an extent, of the Late Bronze Age. This paper argues that the Homeric funerary customs are not a purely literary creation, but rather the result of a mixture of traditions, contemporary customs and collective memory. This will be achieved through a survey of archaeological and written evidence pertaining to Late Bronze Age and Iron Age burial traditions, ranging from Hittite Anatolia to Central Europe, and in doing so suggest the possible origins, both geographically and chronologically, of ‘Homeric’ mortuary practices.
Byzantine or Western European inspirations? Monumental architecture on the borderlands: the case study of medieval Chełm (south-east Poland)
Authors: Buko Andrzej 
Published: September 2022

Abstract
Chełm – located today on the Polish-Ukrainian border –for over a century has attracted the attention of numerous scholars. The town had been rebuilt by Daniel Romanovich, the Halych-Volhynian prince who was crowned in 1253 by Pope Innocent IV and recognized as the king of Ruthenia – which was an unusual event in medieval Europe. For here we have a ruler who belonged to the Orthodox Church accepting a papal crown and the Catholic faith. In such circumstances, some time before the middle of the 13th century, Daniel decided move his seat from Halych to Chełm, situated on the western periphery of his domain. The new city became not only a main seat, but also the real capital of the Halych-Volhynian Princedom. Here, on Cathedral Hill, excavations revealed the remains of the medieval basilica and a multi-element residence. At the same time, new discoveries were made in the city outskirts – namely, two masonry towers and an enigmatic column. The interdisciplinary archaeological research carried out by the author show an architectural complex and many archaeological finds unique in this part of Europe, ones inspired by the traditions of ancient Rome, the Byzantine East, and patterns known at that time in the Latin West.
Attitudes Toward Global and Local Consumer Culture and the Meanings of Brands
Authors: Kim Jung Seek 
Published: September 2022

Abstract
While the rapid worldwide integration has facilitated the emergence of global consumer culture (GCC), local consumer culture (LCC) still holds a strong influence. Brands, be they global or local, are critical marketplace resources in consumer culture for constructing individual and collective identities. As attitudes toward GCC and LCC guide consumers’ choice between global and local brands, the article addresses which brand meanings (functions) drive the choice and use of brands by consumers embracing GCC/LCC. Theoretically, I advance the literature by connecting GCC/LCC and reactions to brand stimuli. Specially, I examine correlations between the two attitudinal constructs and the salience of four brand meanings: quality, personal identity (self-identity, group-identity, and status), values (similar to social responsibility), and traditions. The results suggest that global brands should focus on personal identity, but not quality in positioning and communications. Local brands should develop their iconic status through ties with tradition and heritage, but not by personal identity. Thus, personal identity and traditions are the most important brand associations to be utilized by global and local brands.
Politeness, performance, and pointing: gesture in Chinese reality television
Authors: Schleh Lysander 
Published: September 2022

Abstract
This study examines the use of gesture by participants of the reality television show Sisters Who Make Waves. Based on 23.5 h of footage involving 30 participants, the analysis focuses on gestural communication by the female participants, who must straddle a formal/informal communicative environment dictated by the medium of reality television. More specifically, I examine two features of pointing gestures by the participants: social parameters and context constraints. The main interest is how a combination of general cultural norms as well as considerations of the interlocutor’s social status contribute to gesture use. Context constraints and pragmatic concerns are also analyzed regarding the choice of manual or non-manual pointing gestures. These factors are seen to play a strong role in gesture choice. The findings show that the participants are sensitive to these social and contextual variables, especially regarding concepts like saving face, politeness, and friendly intimacy.
Antioxidant activity of ethanol extract and fractions of Piper crocatum with Rancimat and cuprac methods
Authors: Safithri Mega , Nur Faridah Didah , Ramadani Fitri , Pratama Rahadian 
Published: September 2022

Abstract

Objectives
Bioactive compounds of Piper crocatum Ruiz & Pav, which have acted as antioxidants can be used to prevent and treat degenerative diseases such as hyperglycemia, cancer, gout and hypertension. This research aimed to determine the highest antioxidant activity from extract and fractions of P. crocatum leaves and to identify the active compounds such as antioxidants.

Methods
The extraction was performed by maceration with 70% ethanol and then the crude extract was fractionated with three solvents, namely n-hexane, ethyl acetate and water. The identification of antioxidant activity was carried out using Rancimat and CUPRAC. The active compounds was identified using LC-MS (liquid chromatography-mass spectrometry).

Results
The highest of the Rancimat method was obtained from the ethyl acetate fraction with a protective factor value of 1.38. Ten compounds were identified in the ethyl acetate fraction of P. crocatum leaves. An antioxidant activity according to the CUPRAC method showed the highest antioxidant activity in the sample of the n-hexane fraction with a value of 31.9 µmol Trolox/g extract. Thirteen compounds were identified in the n-hexane fraction of P. crocatum leaves.

Conclusions
The highest antioxidant activity was obtained from ethyl acetate and n-hexane fraction. Various active compounds was identified in the highest value sample.
Effectiveness of Inactivated SARS-CoV-2 Vaccines During a Delta Variant Outbreak in Hunan Province, China: A Retrospective Cohort Study
Authors: Yan Xuemei , Dai Zhihui , Wu Qianhui , Wang Xiaolei , Wang Yan , Zeng Ge , Wu Yanpeng , Chen Shengbao , Yi Lan , Yu Hongjie , Gao Lidong 
Published: September 2022

Objective:
This study was aimed at investigating the effectiveness of inactivated COVID-19 vaccines against the Delta variant.

Methods:
We performed a retrospective cohort study of close contacts of people with laboratory-confirmed SARS-CoV-2 infections in Hunan province, China, from July to August 2021. Mixed-effect logistic regression was used to estimate vaccine effectiveness (VE), and analyze the effects of the vaccination status of index cases and the exposure risk level on VE estimation.

Results:
A total of 1,685 close contacts of 126 index cases were included; 835 (49.6%) had received two doses of inactivated vaccines, and the median interval between the 2nd dose and exposure was 48 days (IQR: 41 to 56 days). Full vaccination was defined as two doses at least 14 days before exposure. Adjusted VE estimates for full vaccination were 54.8% (95% CI: 7.7 to 77.9) and 68.4% (95% CI: 8.5 to 89.1) against symptomatic and moderate-to-severe COVID-19, respectively. VE for inactivated vaccines was difficult to observe if index cases had been fully vaccinated. The estimated VE with respect to infection protection was lower among household than non-household contacts.

Conclusion:
Complete primary immunization of two-dose inactivated COVID-19 vaccines protected against SARS-CoV-2 Delta variant infection. Infection risk was higher among vaccinated household contacts than vaccinated non-household contacts.
Structure–Function Dissociations of Human Hippocampal Subfield Stiffness and Memory Performance
Authors: Delgorio Peyton L. , Hiscox Lucy V. , Daugherty Ana M. , Sanjana Faria , McIlvain Grace , Pohlig Ryan T. , McGarry Matthew D.J. , Martens Christopher R. , Schwarb Hillary , Johnson Curtis L. 
Published: September 2022

Aging and neurodegenerative diseases lead to decline in thinking and memory ability. The subfields of the hippocampus (HCsf) play important roles in memory formation and recall. Imaging techniques sensitive to the underlying HCsf tissue microstructure can reveal unique structure–function associations and their vulnerability in aging and disease. The goal of this study was to use magnetic resonance elastography (MRE), a noninvasive MR imaging-based technique that can quantitatively image the viscoelastic mechanical properties of tissue to determine the associations of HCsf stiffness with different cognitive domains across the lifespan. Eighty-eight adult participants completed the study (age 23–81 years, male/female 36/51), in which we aimed to determine which HCsf regions most strongly correlated with different memory performance outcomes and if viscoelasticity of specific HCsf regions mediated the relationship between age and performance. Our results revealed that both interference cost on a verbal memory task and relational memory task performance were significantly related to cornu ammonis 1–2 (CA1–CA2) stiffness (p= 0.018 andp= 0.011, respectively), with CA1–CA2 stiffness significantly mediating the relationship between age and interference cost performance (p= 0.031). There were also significant associations between delayed free verbal recall performance and stiffness of both the dentate gyrus–cornu ammonis 3 (DG–CA3;p= 0.016) and subiculum (SUB;p= 0.032) regions. This further exemplifies the functional specialization of HCsf in declarative memory and the potential use of MRE measures as clinical biomarkers in assessing brain health in aging and disease.SIGNIFICANCE STATEMENTHippocampal subfields are cytoarchitecturally unique structures involved in distinct aspects of memory processing. Magnetic resonance elastography is a technique that can noninvasively image tissue viscoelastic mechanical properties, potentially serving as sensitive biomarkers of aging and neurodegeneration related to functional outcomes. High-resolutionin vivoimaging has invigorated interest in determining subfield functional specialization and their differential vulnerability in aging and disease. Applying MRE to probe subfield-specific cognitive correlates will indicate that measures of subfield stiffness can determine the integrity of structures supporting specific domains of memory performance. These findings will further validate our high-resolution MRE method and support the potential use of subfield stiffness measures as clinical biomarkers in classifying aging and disease states.