bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attitude and influencing factors of patients with schizophrenia toward long-acting injections: A community-based cross-sectional investigation in China
Authors: Sun Yiying , Tong Jie , Feng Ying , Fang Haiping , Jiang Tao , Zhao Liping , Wang Qiang , Yang Yi 
Published: October 2022

BackgroundLow prescription rates of antipsychotic long-acting injections (LAIs) may be a major challenge in the prevention and treatment of schizophrenia. However, there are few studies on the usage and attitude toward LAIs among community-based patients with schizophrenia.MethodsA large community-based cross-sectional investigation was conducted among 6,336 patients with schizophrenia from Shanghai, China from March 1 to June 30, 2021. The structured Attitude and Status toward Treatment of Community Patients with Schizophrenia Questionnaire (AST-CSQ) was used to investigate the attitude and influencing factors of community-dwelling patients with schizophrenia toward LAIs.ResultsAmong the 6,336 participants, the average age was 49.28 ± 11.23. The rate of agreement to LAI antipsychotics among participants was 3.16% (n = 200). The family financial resources, care ability, and disease course of the LAIs group were less than those of the non-LAIs group. However, the LAIs group had higher immediate family guardianship, social activity, previous hospitalization, number of hospitalization, outpatient adherence, previous antipsychotic use, antipsychotic adherence, and attitude toward oral antipsychotics than the non-LAIs group, with significant differences between the two groups (p &lt; 0.05). Furthermore, age (β = −0.036, OR 0.964, 95% CI 0.947–0.982), marital status (β = 0.237, OR 1.267, 95% CI 1.002–1.602), care ability (β = 0.709, OR 2.032, 95% CI 1.437–2.875), outpatient adherence (β = −0.674, OR 0.510, 95% CI 0.358–0.725), antipsychotic adherence (β = 0.920, OR 2.509, 95% CI 1.092–5.764), and attitude toward oral antipsychotics (β = −1.357, OR 0.258, 95% CI 0.103–0.646) were significant predictors of attitude toward LAI antipsychotics (p &lt; 0.05).ConclusionsThe community-dwelling patients with schizophrenia in China had a low willingness to use LAIs. Patients of a younger age, more hospitalizations, and a shorter course of disease were prone to be more willing to accept LAIs. The patients' age, marital status, care ability, outpatient adherence, antipsychotic adherence, and attitude toward oral antipsychotics were important predictor of patients' attitudes toward LAIs. Under the global deinstitutionalized management model of mental disorders, these results highlight an urgent problems for public mental health service providers and policy-makers and provide more solutions for them.
Psychometric evaluation of the healthy aging activity engagement scale
Authors: Lu Tingting , Kong Linghui , Zhang Huijun 
Published: October 2022

ObjectiveThe aim of this study was to translate the Healthy Aging Activity Engagement Scale (HAAE) into Chinese and validate its psychometric properties in the middle-aged and elderly population.MethodsA total of 424 middle-aged and elderly people were recruited from China's Jiangsu Province, Liaoning Province, Shandong Province, and Heilongjiang Province. Cronbach's α co-efficient, split-half reliability, and test-retest reliability were used to evaluate the reliability of the translated scale. Expert consultation was used to evaluate the content validity of the translated scale. Exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) were used to evaluate the structural validity of the scale.ResultsThe Cronbach's α co-efficient of the Chinese version of HAAE was 0.965 and the Cronbach's α co-efficient of the dimensions ranged from 0.898 to 0.957. The split-half reliability was 0.807, and the test-retest reliability was 0.850. The content validity index of the scale (S-CVI) was 0.969. A total of three common factors were extracted from the EFA. The CFA validated the explored 3-factor structure, and the indicators were fitted well (χ2/df = 1.393, comparative fit index = 0.982, goodness- of- fit index = 0.911. Tucker-Lewis Index = 0.981 and root mean square error of approximation = 0.030).ConclusionThe translated Chinese version of HAAE had suitable reliability and validity in the middle-aged and elderly population. The translated scale will be used to evaluate the level of healthy aging among middle-aged and elderly people in Chinese mainland. Furthermore, it also can provide some health advice for clinical patients.
ORP should not be used to estimate or compare concentrations of aqueous H2: An in silico analysis and narrative synopsis
Authors: LeBaron Tyler W. , Sharpe Randy 
Published: October 2022

Oxidation reduction potential (ORP) has become a commonly used measurement to characterize functional beverages, specifically alkaline ionized water and hydrogen water. Numerous health benefits including antioxidant effects have been attributed to a negative ORP value. A greater negative ORP value is often incorrectly interpreted to mean a greater degree of health benefits and/or a high concentration of H2. Some hydrogen meters use the Nernst equation to calculate the concentration of H2 based on the measured ORP value. Unfortunately, due to the fundamental issues with the ORP meter, the calculated H2 value may be very inaccurate. Using the Nernst equation, we performed an in silico analysis of the ORP as a function of pH, temperature, and H2 concentration. Our analysis shows that a one unit increase in pH (e.g., 7–8) influences the ORP by as much as increasing the H2 concentration by 100 times (e.g., 1–100 mg/L). Similarly, at a saturated H2 concentration (1.57 mg/L) and pH 7, every ∆T of 20 °C changes the ORP by ≈ 30 mV. This is comparable to changing the H2 concentration by a factor of 10 (0.1 mg/L to 1 mg/L). Finally, to measure H2 within 0.1 mg/L, ORP meters need to have an accuracy of about 0.8 mV. However, ORP meters have an error range of at least ±10 mV, which corresponds to a potential error in measured H2 concentration of nearly 2 mg/L (≈125% error). This analysis shows that pH, temperature, and the intrinsic ORP errors can individually influence the ORP greater than the entire contribution of dissolved H2 within normally used ranges. In fact, this can easily result in a water sample with a greater negative ORP than another despite having significantly less H2. This makes it impossible to consistently determine if one water sample has more H2 than another water sample. Therefore, we can only conclude, based on a negative ORP reading, that, excluding the possibility of other reductive redox couples, some level of dissolved H2 is present in the water. Accordingly, ORP and ORP-based H2 meters are not recommended for testing or comparing the concentration of H2 in water. Experimental studies are warranted to determine if the ORP error is as great as or greater than what is predicted via this in silico analysis.
A novel integrated angioscope-laser system for atherosclerotic carotid artery occlusion: Feasibility and techniques
Authors: Zhang Boqian , Zhang Guiyun 
Published: October 2022

IntroductionAtherosclerotic extracranial carotid artery stenosis accounts for about 20%–30% of all strokes, which is one of the leading causes of adult morbidity and mortality. Although carotid endarterectomy (CEA) is still the mainly operational manner for atherosclerotic carotid artery stenosis/occlusion (ACAS/ACAO), and carotid angioplasty and stenting (CAS) have been used as an alternative, both CEA and CAS have limitations of their own, such as extensive invasiveness and in-stent restenosis.MethodsIn this study we established a novel interventional system in vitro to take advantage of both CEA and CAS. Twenty consecutive carotid atherosclerotic plaques were harvested from the patients who underwent CEA. The plaques were randomized into two groups and inserted into the pruned and sutured descending aortas of the swine in vitro. The ZebraScope™ was modified with a protective device on its flexible tip, so that the plaque could be dissected from the wall of parent carotid artery and ablated completely without damage to the carotid artery. The holmium:YAG (Ho:YAG) and thulium fiber laser (TFL) generators were alternately used when needed.ResultsAll the carotid atherosclerotic plaques were completely ablated by Ho:YAG laser and/or TFL. The Ho:YAG laser was more effective for the atherosclerotic plaques with severe calcification, while the TFL was more suitable for those with moderate calcification. There were still some thermal injury spots on the inner wall of the parent carotid artery caused by the laser in the non-protected group B. In the protected group A, on the contrary, there was no even a thermal injury spot was found on the relevant location except for one sample. The difference of ablating duration was statistically significant between group A (36.5 ± 4.79 min) and group B (63.4 ± 6.55 min) (P &lt; 0.01).ConclusionAccording to our knowledge, this is the first attempt to ablate carotid atherosclerotic plaques assisted by the ZebraScope™ in vitro. The protective and dissecting device on the tip of the angioscope makes it safe and visible when the ablation is performed to carotid atherosclerotic plaques. The Ho:YAG laser and TFL are effective and safe for ablating the plaque in vitro.
Effect of Sulfate, Citrate, and Tartrate Anions on the Liquid-Liquid Equilibrium Behavior of Water + Surfactant
Authors: Jimenez Otto A. Q. , Costa Josiel M. , de Souza Bruno R. , Medeiros Abimael C. , Monteiro-Junior Edson G. , Basso Rodrigo C. 
Published: October 2022

Cloud point extraction is a versatile method aimed at separating compounds from complex mixtures and arouses great technological interest, particularly among the biochemical industries. However, one must have deep knowledge of the liquid–liquid equilibrium behavior of systems to properly use the method. Thus, we used thermodynamic parameters to evaluate the effect of citrate, sulfate, and tartrate anions on the phase separation of water + Triton X-114® mixtures at 283.2 K, 293.2 K, and 303.2 K. In these systems, increasing the temperature and the anion molar fraction expanded the biphasic region in the following order: C6H5O73-> SO42- > C4H4O62−. Unlike other studies based on the Hofmeister series, the Gibbs free energy of micellization correlated the anion effect on the biphasic region with the spontaneity of the micelle formation. The water molecules structured around these anions were evaluated according to the shell volume of the immobilized water by electrostriction, volume of water around the hydration shell, Gibbs free energy of hydration, and Gibbs free energy of electrostriction (ΔGel12). The citrate anion presented a higher ΔGel12 of −1781.49 kJ mol−1, due to the larger number of electrons around it. In addition, the partition coefficient of the surfactant in the two liquid phases revealed a linear dependence upon the anion mole fractions by following the previous anion sequence and temperature in the phase separation.
Precision Enhancement of Wireless Localization System Using Passive DOA Multiple Sensor Network for Moving Target
Authors: Chen Chien-Bang , Lo Tsu-Yu , Chang Je-Yao , Huang Shih-Ping , Tsai Wei-Ting , Liou Chong-Yi , Mao Shau-Gang 
Published: October 2022

Determining the direction-of-arrival (DOA) of any signal of interest has long been of great interest to the wireless localization research community for military and civilian applications. To efficiently facilitate the deployment of DOA systems, the accuracy of wireless localization is critical. Hence, this paper proposes a novel method to improve the prediction result of a wireless DOA localization system. By considering the signal variation existing in the complex environment, the actual location of the target can be determined including the maximum prediction error. Moreover, the scenario of the moving target is further investigated by incorporating the adaptive Kalman Filter algorithm to obtain the prediction route of the flying drone based on the accuracy assessment method. This proposed adaptive Kalman Filter is a high-efficiency algorithm that can filter out the noise in the multipath area and optimize the predicted data in real-time. The simulation result agrees well with the measured data and thus validates the proposed DOA system with the adaptive Kalman Filter algorithm. The measured DOA of the fixed radiation source obtained by a single base station and the moving route of a flying drone from a two-base station localization system are presented and compared with the calculated results. Results show that the prediction error in an outdoor region of 500×500 m2 is about 10–20 m, which demonstrate the usefulness of the proposed wireless DOA system deployment in practical applications.
INNOVATIVE PEDAGOGICAL MANAGEMENT AS EDUCATIONAL THEORY AND PRACTICE
Authors: BABENKO I. , SHKOLJAR S. , DZEKUN Y. 
Published: October 2022

The article considers innovative pedagogical management as a means of transforming pedagogical systems into a qualitatively new state, as a tool for building a new, more prosperous and developed society as a whole. The main changes that every manager needs to make if he wants his educational institution to be able to fully realize its potential are outlined.
Innovative pedagogical management involves solving two interrelated tasks: first, the management of technological, organizational and economic innovations; secondly, managing the process of development and distribution of new highly effective pedagogical technologies, new methods, techniques and tools of teaching, education and personal development. Its characteristic features are systemic, collegiality, democracy, flexibility in the preparation, adoption and implementation of management decisions and more.
In today's dynamic environment, the long-term effectiveness of the educational institution is increasingly dependent on targeted changes that are continuous, affecting the mode of its operation by the management of controlled adjustments to preset statistical indicators. To achieve recognition and satisfaction of students, parents, the public, the head of a modern educational institution must not only create a functioning system that works in a certain, consistently repetitive mode, but also be able to update it and thus bring it into dynamic balance or harmony with changing environments.
The authors study the process of creating and using educational innovations, emphasizing the importance of translating it from spontaneous to purposeful, planned. It is shown that the main directions and tasks of innovative management should be considered: development and implementation of a unified innovation policy; defining a system of strategies, projects, programs; resource provision and control over the course of innovation activity; training and education of teachers; formation of target teams, groups that implement solutions to innovation projects, creating an innovation environment.
The content of innovative pedagogical management in the educational institution involves, firstly, a targeted policy on the organization of education based on new information technologies in traditional educational institutions, and secondly, the development of new types of organizational structures, institutional forms characteristic of modern education. Formation and development of the system of innovative pedagogical management is evolutionary in nature and is achieved through the coordinated actions of the entire teaching staff.
TOWARDS LEARNING IN THE DIGITAL SPACE: TEACHERS’ IN-SERVICE AND CIVIL SERVANTS’ TRAINING IN THE SYSTEM OF ADULTS EDUCATION
Authors: BODYK O. , SHEREDEKA G. , SALAHUB L. 
Published: October 2022

This article focuses on the implementation of digitalization and its features into the teachers’ in-service and civil servants’ training in the context of modern Ukrainian postgraduate pedagogical education. It is one of the actual themes and important necessities of the present situation.
The main objective of the study is to summarize and generalize the practical experience of Ukrainian scientists on the peculiarities of in-service training of subject teachers and civil servants and to find effective mechanisms for working with adults in the digital space.
To achieve the objective some problems have been solved such as: to analyze technical ability and accessibility to work in modern online and offline conditions during teachers' in-service training, to determine the steps of actions while introducing the online educational hub platform. It was stated that the process should be focused on participants’ hard and soft-skills development.
While writing this article the following research methods have been used: 1) theoretical: system analysis, abstraction, generalization, comparison, systematization and classification of the received information and its interpretation; 2) empirical: method of survey and questionnaire, method of comparative analysis of the obtained results, expert evaluation.
The conclusions show that a modern educational environment should consist of two components: an online platform that will accelerate training services provision and an educational hub equipped with up-to-date facilities. It will also help us to promote the Institute's educational services not only online but offline using modern educational methodologies. In general, the project will promote more active cooperation between territorial communities’ of Ukraine.
ASPECTS OF FORMATION OF CRITICAL THINKING OF FUTURE TEACHERS OF MATHEMATICS IN THE PROCESS OF STUDYING PROFESSIONALLY ORIENTED DISCIPLINES
Authors: KOVALENKO O. , MOSKALENKO O. , MOSKALENKO Yu. , CHERKASKA L. 
Published: October 2022

The ability to think critically is an important quality of the individual, but it is now, in the face of social and economic changes, that it becomes essential. Critical thinking is an integrative characteristic, since it involves the generalization, unification and development of a whole range of qualities, skills and socially important features that contribute to the comprehensive harmonious development of the personality.
For a future teacher to succeed in his professional activity need, in particular: the ability to perceive new information, to comprehend it, to balance different points of view and to critically comprehend them, the ability to critically understand professional situations, objectively assess their capabilities. For him, criticality is therefore a vital quality that ensures the development of analytical and reflective abilities.
Since critical thinking does not automatically arise as a by-product of learning, it is necessary to systematically work on its improvement.
Development of critical thinking is a mandatory requirement to the results of the first (bachelor) level of higher education program of the subject specialty 014.04 Secondary Education (Mathematics) in the Poltava V. G. Korolenko National Pedagogical University in terms of formation of general and professional competence of the graduate.
An important role in the synthesis of the student’s knowledge in the direction of his needs as a future teacher of mathematics belongs, in particular, to such professionally-oriented bachelor disciplines as «Methods of Teaching Mathematics», «Selected Questions of Methods of Teaching Mathematics», «Elementary Mathematics». In the process of teaching these disciplines, the development of critical thinking occurs in three aspects: sociocultural (through the organization of the educational process in relation to life and professional situations), technological (through the formation of sustained interest, motivation of educational activity, search for information aimed at solving the task, its awareness and reflection), methodical (through a set of methodical methods, providing assessment, self-control, criticism, forecasting). Practical and methodical tasks, which correspond to the areas identified in the research process, are a fundamental basis for the development of critical thinking as an important component of the professional competence of future highly qualified teachers of mathematics.
ETHICAL COMPETENCE - A BASIC COMPONENT OF TEACHER PROFESSIONALISM
Authors: KUCHAI T. , KUCHAI O. , ROKOSOVYK N. , ZOROCHKINA T. 
Published: October 2022

The article considers ethical competence as a basic component of the teacher's professionalism. The process of forming ethical competence should be systematic and requires the application of a holistic mechanism of professional development of the student's personality during training. The teacher's abilities regarding ethical competence, as well as its components, are highlighted.
A necessary condition for the formation of students' ethical competence is the use of the latest pedagogical technologies and teaching methods in addition to traditional ones. The process of forming a teacher's ethical competence is complex, dynamic, multifaceted and multifactorial. The substantive basis of ethical competence is pedagogical ethics. Pedagogical ethics studies the features, content, principles and functions of pedagogical morality, the nature of the teacher's activity and his moral relationships in the pedagogical environment, develops the basics of pedagogical etiquette, which is a set of rules for teacher communication and behavior. Ethics is not reduced to a certain system of sanctions in pedagogical activity, because its task is to explain the social and psychological expediency of observing certain professional norms and rules. It is ethics, from the standpoint of a holistic approach to the individual, that insists on considering the education and upbringing of the individual as its spiritual saturation, which unfolds in spiritual dialogue, communication between equal subjects. The vocation of a teacher is not only the transfer of knowledge, abilities and skills, but also the comprehensive development of the student's abilities and capabilities, the upbringing of a decent, responsible, conscious citizen of the country. The professional activity of a teacher is based on the supremacy of universal human values, norms and principles of morality. When performing it, the teacher acts as the bearer of responsibilities in relation to: the student, the student's parents, the professional pedagogical community as a whole and individual teachers, himself, society.
Effectiveness Test of Green Betel Leaf Extract (Piper betle L.) on the Growth of Staphylococcus aureus
Authors: Aprilia Riris Grace , Premita Yohania , Simbolon Boyke Marthin , Bt. Hasan Riyani Susan 
Published: October 2022

Background: Diseases due to infection where one of the causes is Staphylococcus aureus is one of the biggest problems faced today. Treatment using penicillin antibiotics tends to cause resistance and side effects, so people prefer to overcome them by means of self-medication or the use of traditional ingredients such as betel leaf. The purpose of the study was to examine the effect of green betel leaf extract (Piper betle L.) on the growth of Staphylococcus aureus on the antibacterial activity.
Methods: This study is experimental research in vitro using a well diffusion method. The betel leaf was extracted using the maceration method and made into concentrations of 5%, 10%, 15%, and 20%.
Results: The average diameter of the inhibition zones was 9.82 mm, 9.11 mm, 9.28 mm, and 9.01 mm at concentrations of 5%, 10%, 15%, and 20%, sequentially.
Conclusion: The antibacterial activity of betel leaf extract in the overall concentration and the most optimal concentration was 5% at 9.82 mm.