bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gravfunn på Hov gård
Authors: Roth Niemi Anja 
Published: November 2022

I forbindelse med registrering på Hov gård på Gimsøya i Lofoten høsten 2020 kom det fram skjelettdeler fra et menneskes underkropp. Ved Universitetsmuseets utgravning seinere samme år ble det dokumentert en godt bevart og tilnærmet uforstyrret halv grav, som omfattet overkroppen. Den døde har vært plassert liggende på siden med overkropp og ansiktet vendt delvis oppover og beina trukket opp. Kroppen var tildekket av et tynt lag trevirke eller en matte av neverflak. Grava tilhørte en mann som døde da han var mellom 25 og 34 år. Dødsårsaken er ukjent. Han har hatt et brudd i nedre del av ryggen, som kan ha gitt en del smerter. Kostholdet var sterkt innrettet mot maritime ressurser, og har trolig omfattet sjøpattedyr som sel. Gravgodset inneholdt en øks, to kniver, en kam, ildflint og en mulig holk/fal fra spyd. Grava er datert til merovingertid og første halvdel av 700-tallet, primært ut fra typologiske trekk ved gjenstandsmaterialet. Det antas at mannen i grava tilhørte den ledende familien på gården og derigjennom det øvre samfunnslaget på Gimsøya. Han har trolig nytt en relativt høy status lokalt, men inngikk neppe i det øvre aristokratiet i regionen.
Research agendas for alcohol policymaking in the wider world
Authors: Room Robin , Laslett Anne-Marie , Miller Mia , Waleewong Orratai , Assanangkornchai Sawitri , Beccaria Franca , Benegal Vivek , Borges Guilherme , Gmel Gerhard , Graham Kathryn , Hao Wei , Mäkelä Pia , Morojele Neo , Hanh Hoang Thi My , Obot Isidore , O'Brien Paula , Pinsky Ilana , Sornpaisarn Bundit , Stockwell Tim 
Published: November 2022

From comparisons of World Health Organization statistics, it is clear that people in lower-income countries experience more harms per litre of alcohol and different types of harms compared to those from higher-income countries. Yet studies in higher-income countries dominate research on policies to prevent alcohol problems. The paper reports on results of collaborative work to map priority areas for research relevant to low- and middle-income countries. Research focus areas were identified and discussed among potential coauthors from diverse fields with relevant knowledge, with agreement reached on an initial list of seven research priority areas. Areas identified include: (1) the effects of choices (e.g., national vs. local, monopoly vs. licensing system) in organising the alcohol market; (2) involvement/separation of alcohol industry interests in decisions on public health regulation; (3) options and effectiveness of global agreements on alcohol governance; (4) choices and experience in controlling unrecorded alcohol; (5) means of decreasing harm from men’s drinking to family members; (6) strategies for reducing the effects of poverty on drinking’s role in harms; and (7) measuring and addressing key alcohol-induced low-and middle-income country (LMIC) health harms: infectious diseases, injuries, digestive diseases. Paths ahead for such research are briefly outlined.
Chemical Contaminants Assessment Influencing the Proper Functioning of the Waste Water Treatment Plant in a Brewing Factory: Case of SABC Yaounde -Cameroon
Authors: Félicité Obono Mba , Gael Moudio Privat , Diane Madomguia , Armand Abdou Bouba 
Published: November 2022

The present study were carried out in the brewing factory of Cameroon (SABC) Yaoundé focuses on the evaluation of chemical contaminants influencing the wastewater treatment plant.
Standard methods of analysis of physicochemical parameters of wastewater in anaerobic sludge were done according to Waterleau [1].
The information collected made it possible to evaluate chemical contaminants according to the use of water, water solubility and dangerousness.
It was found that, chemical contaminants are mostly disinfectants (30%) and cleaning products (15%). Nevertheless, there are others used for pH regulation, such as beer stabilizers, etc. The wastewater treatment plant has shown overall good yields. The temperature that varies between 31°C and 32°C, characterise an optimal temperature for the metabolism of microorganisms. The pH oscillates between 7 and 10 characterise majority the alkaline waters. This study shows that the presence of chemical contaminants in discharge water which came from different part of the factory and were other chemical are used, influences microorganism area and can affect their health of purification microorganisms by acting on the physico-chemical parameters of wastewater and sludge.
Management of cognitive and negative symptoms in schizophrenia
Authors: Maroney Megan 
Published: November 2022

Abstract
Currently available antipsychotics provide only modest benefit in managing the cognitive and negative symptoms of schizophrenia even though these symptoms are often the most impairing in patients' daily lives. Certain antipsychotics may have slight benefits over others, and several nonpharmacologic and pharmacologic adjunctive treatments have been evaluated in recent clinical trials. Recently published meta-analyses and clinical studies of such treatments are reviewed. Potential strategies to manage cognitive and negative symptoms, including deprescribing of medications that may exacerbate these symptoms, are described using theoretical case examples.
Expanding Bodies: Pedagogical Models for Pluralistic Spatialities
Authors: Riano Quilian 
Published: November 2022

AbstractDepictions of ideal bodies, whether by Leonardo da Vinci or Le Corbusier, and their importation into the strictures of architecture and space‐making generally, ignore a multitude of other bodies. Quilian Riano, Interim Dean of Pratt Institute's School of Architecture in Brooklyn, New York, looks at these other bodies and describes an inclusive, pluralistic future for architecture and the way it is taught.
From Altars to Alterity: Offerings and Inheritances for Queer Vietnamese Kin
Authors: Nguyen Thompson Cong 
Published: November 2022

AbstractAs a child of Vietnamese refugees who settled in suburban Mississauga in Ontario, Thompson Cong Nguyen describes his hybrid cultural identity, queerness and complex inter‐relations with the historic ritual of his ancestors and the divergent manifestations of Canadian society. He does so through the design of the set of transportable altars that were part of his MArch thesis at the Azrieli School of Architecture and Urbanism at Carleton University in Ottawa.
Enhanced Elastic Migration of Magnesium Cations in alpha‐Manganese Dioxide Tunnels Locally Tuned by Aluminium Substitution
Authors: Ding Yaxi , Zhang Siwen , Li Jiazhuo , Sun Ying , Yin Bosi , Li Hui , Ma Yue , Wang Zhiqiao , Ge Hao , Su Dawei , Ma Tianyi 
Published: November 2022

AbstractThe harsh conditions of large hydrated ion radius of Mg2+ cations and the strong electrostatic interaction with the host material put forward higher requirements for high‐performance aqueous magnesium ion (Mg2+) energy storage devices. Herein, substituted aluminium ions (Al3+) doped α‐MnO2 materials are prepared. The introduction of Al3+ cations adjust the local chemical environment inside the tunnel structure of α‐MnO2 and precisely regulates the diffusion behavior of inserted Mg2+ cations. The shortened oxygens’ distance and abundant oxygen defects result in a substantially enhanced elastic migration pattern of Mg2+ cations driven by strengthened electrostatic attraction, which brings the lower diffusion energy barrier, improved reaction kinetics, and adaptive volume expansion as evidenced by Climbing Image‐Nudged Elastic Band density function theory calculations coupled with experimental confirmation in X‐ray photoelectron spectroscopy, electron paramagnetic resonance, and galvanostatic intermittent titration technique. As a result, this rationally designed cathode exhibits a high reversible capacity of 197.02 mAh g‐1 at 0.1 A g‐1 and stable cycle performance of 2500 cycles with 82% retention. These parameters are among the best of Mg‐ion capacitors reported to date. This study offers a detailed insight into the local tunnel structure tunning effect and opens up a new path of modification for tunnel‐type structural materials.
A Dual‐Locked Tandem Fluorescent Probe for Imaging of Pyroptosis in Cancer Chemo‐Immunotherapy
Authors: Wang Xinzhu , He Shasha , Cheng Penghui , Pu Kanyi 
Published: November 2022

AbstractReal‐time imaging of programmed cancer cell death (PCD) is imperative to monitor cancer therapeutic efficacy and tailor therapeutic regimens; however, specific in vivo detection of intratumoral pyroptosis remains challenging. Herein, a dual‐locked and tandem activatable probe (DTAP) is reported for near‐infrared fluorescence (NIRF) imaging of intratumoral pyroptosis during cancer chemo‐immunotherapy in living mice. The probe comprises a hemicyanine dye dual‐locked with an enzyme‐responsive moiety that can be tandemly cleaved by pyroptosis‐related biomarker (Caspase‐1) and cancer biomarker (GGT) to turn on its NIRF signal. As pyroptosis plays a vital role in triggering anti‐tumor immune responses, the activated signal of DTAP correlates well with the population of tumor‐infiltrating cytotoxic T lymphocytes and tumor growth inhibition, consequently permitting the prediction of cancer therapeutic efficacy. This study also provides a non‐invasive technique to study the regulatory mechanism of pyroptosis in cancer therapy and to optimize cancer chemo‐immunotherapies for precision medicine.
Impact of Ligands on the Performance of PbS Quantum Dot Visible–Near‐Infrared Photodetectors
Authors: Bothra Urvashi , Albaladejo‐Siguan Miguel , Vaynzof Yana , Kabra Dinesh 
Published: November 2022

AbstractSolution‐processed lead sulfide quantum dots (PbS QDs) are an excellent candidate for photodetector applications because they exhibit broadband absorption, a wide range of tuneable bandgaps, high stability in air, and mechanical flexibility. However, a crucial criterion for the fabrication of high‐performance photodetectors is the selection of the ligands, which can facilitate charge carrier transport between the PbS QDs and passivate the surface defects. In this work, the authors have studied the effect of traps on the performance of PbS QD photodetectors that are fabricated using different types of ligands, using intensity‐dependent photoresponse dynamics. The best devices with lead halide ligands show a dark current density of 5 × 10−9 A cm−2 at −0.2 V, which is one of the lowest values reported thus far for solution‐processed PbS QD‐based photodetectors. Moreover, these devices show a high linear dynamic range (≈90 dB) and high detectivity (>1013 Jones), in addition to an f‐3 dB of greater than 100 kHz without the application of an external voltage bias at a wavelength of 784 nm. These results suggest that with an appropriate selection of ligands, solution‐processed photodetectors with a lower density of traps and a better device performance can be fabricated.
Optical Control of Aggregation‐Induced Emission Shift by Photoisomerizable Precipitant in a Liquid Droplet Microresonator
Authors: Zhao Shuai , Yamagishi Hiroshi , Norikane Yasuo , Hayashi Shotaro , Yamamoto Yohei 
Published: November 2022

AbstractEmission‐switchable fluorophores often include stimuli‐responsive units in their molecular structures. This strategy works well, but the applicable compounds are limited to the derivatives of several kinds of photochromic molecules such as diarylethene, azobenzene, and spiropyran. Here, this work presents a simple methodology based on a photoresponsive precipitant for achieving color‐switchable photoluminescence. A luminescent dye, cyano‐substituted oligo(phenylenevinylene) (COPV), features both twisted intramolecular charge transfer and aggregation‐induced emission shift properties, leading to the change in the luminescence color from green to red upon precipitation. The COPV, together with photoisomerizable precipitant azobenzene (C6), is doped into spherical droplets of epoxy resin (ER) in a liquid state. The photoisomerization of C6 induced by UV irradiation and heating alternatively precipitates out and dissolves COPV in ER and changes the photoluminescence color, while maintaining the optical microresonator properties. This study will open a promising way for assembling/disassembling novel emission color‐switchable systems.
Electrochemically Induced Regio‐ and Stereoselective (E)‐β‐C(sp2)−H Trifluoromethylation and Arylsulfonylation of Enamides
Authors: Zhang Fukuan , Zhao Xuefei , Zhang Jie , Zhao Lili , Li Lin , Yang Jiayi , Li Hao , Luo Haiqing 
Published: November 2022

AbstractHerein, we disclosed an electrochemically induced method for the regio‐ and stereoselective (E)‐β‐C(sp2)−H trifluoromethylation of enamides by employing readily available and inexpensive Langlois’ reagent (CF3SO2Na). Preliminary mechanistic studies indicate the involvement of free radicals in the process. The exogenous oxidant‐free reaction proceeds in an undivided electrochemical cell under mild conditions and allows for the accomplishment of the trifluoromethylation products with exclusive E‐selective control. The methodology is featured by catalyst‐free, simple setup, and broad substrate scopes of enamides with good functional group tolerance. Using ArSO2Na as the coupling partner, the corresponding (E)‐β‐C(sp2)−H arylsulfonylated enamides products are obtained under standard reaction conditions.magnified image
Regulation of Transgene Expression by the Natural Sweetener Xylose
Authors: Galvan Silvia , Madderson Oliver , Xue Shuai , Teixeira Ana P. , Fussenegger Martin 
Published: November 2022

AbstractNext‐generation gene and engineered‐cell therapies benefit from incorporating synthetic gene networks that can precisely regulate the therapeutic output in response to externally administered signal inputs that are safe, readily bioavailable and pleasant to take. To enable such therapeutic control, a mammalian gene switch is designed to be responsive to the natural sweetener xylose and its functionality is assessed in mouse studies. The gene switch consists of the bacterial transcription regulator XylR fused to a mammalian transactivator, which binds to an optimized promoter in the presence of xylose, thereby allowing dose‐dependent transgene expression. The sensitivity of SWEET (sweetener‐inducible expression of transgene) is improved by coexpressing a xylose transporter. Mice implanted with encapsulated SWEET‐engineered cells show increased blood levels of cargo protein when taking xylose‐sweetened water or coffee, or highly concentrated apple extract, while they do not respond to intake of a usual amount of carrots, which contain xylose. In a proof‐of‐concept therapeutic application study, type‐1 diabetic mice engineered with insulin‐expressing SWEET show lowered glycemia and increased insulin levels when administered this fairly diabetic‐compliant sweetener, compared to untreated mice. A SWEET‐based therapy appears to have the potential to integrate seamlessly into patients’ life‐style and food habits in the move toward personalized medicine.
Emergence of MXene and MXene–Polymer Hybrid Membranes as Future‐ Environmental Remediation Strategies
Authors: Khosla Ajit , Sonu  , Awan Hafiz Taimoor Ahmed , Singh Karambir , Gaurav  , Walvekar Rashmi , Zhao Zhenhuan , Kaushik Ajeet , Khalid Mohammad , Chaudhary Vishal 
Published: November 2022

AbstractThe continuous deterioration of the environment due to extensive industrialization and urbanization has raised the requirement to devise high‐performance environmental remediation technologies. Membrane technologies, primarily based on conventional polymers, are the most commercialized air, water, solid, and radiation‐based environmental remediation strategies. Low stability at high temperatures, swelling in organic contaminants, and poor selectivity are the fundamental issues associated with polymeric membranes restricting their scalable viability. Polymer‐metal‐carbides and nitrides (MXenes) hybrid membranes possess remarkable physicochemical attributes, including strong mechanical endurance, high mechanical flexibility, superior adsorptive behavior, and selective permeability, due to multi‐interactions between polymers and MXene's surface functionalities. This review articulates the state‐of‐the‐art MXene–polymer hybrid membranes, emphasizing its fabrication routes, enhanced physicochemical properties, and improved adsorptive behavior. It comprehensively summarizes the utilization of MXene–polymer hybrid membranes for environmental remediation applications, including water purification, desalination, ion‐separation, gas separation and detection, containment adsorption, and electromagnetic and nuclear radiation shielding. Furthermore, the review highlights the associated bottlenecks of MXene–Polymer hybrid‐membranes and its possible alternate solutions to meet industrial requirements. Discussed are opportunities and prospects related to MXene–polymer membrane to devise intelligent and next‐generation environmental remediation strategies with the integration of modern age technologies of internet‐of‐things, artificial intelligence, machine‐learning, 5G‐communication and cloud‐computing are elucidated.
Newly Synthesized High‐k Polymeric Dielectrics with Cyclic Carbonate Functionality for Highly Stability Organic Field‐Effect Transistor Applications
Authors: Xu Ting , Liu Yifan , Bu Yunlong , Shu Shiyao , Fan Shuangqing , Cao Minghui , Liu Tong , Zou Jiawei , Su Jie 
Published: November 2022

AbstractOrganic field‐effect transistors (OFETs) with low‐voltage‐operating high‐stability are regarded as one of the key components of future electronics. However, it remains a challenge to enhance bias–stress stability, mechanical durability and environmental adaptability while reducing the operating voltage of the flexible OFETs. In this study, a new strategy of introducing high‐dipole‐moment groups into polymer side chains to enhance the intensity of polarization was proposed. This strategy can redirect cyclic carbonate side chains of high‐dipole groups under the action of electric fields and realize stable operation and efficient charge transfer. The experiments showed that high‐performance flexible OFETs were mainly attributed to the synthesized polymers through molecular structure designing which not only have high dielectric constant (k > 5) and high electrical insulating property but also favor the growth of organic semiconductor films. The flexible OFETs still showed excellent mechanical flexibility, high electrical, thermal and humidity stability. In addition, highly OFETs were applied into a floating‐gate memory with fullerene (C60) embedded charge memory layer and an integrated one‐transistor‐one‐transistor memory cell. They exhibited excellent memory performance with a large memory window (8.5 V), current ratio (103), stable retention (2 × 104 s), cyclic endurance (200 cycles), multi‐level memory (over 4 levels) and non‐destructivity.
Nanostructuring‐Promoted Non‐Equilibrium Phase Transformation of Bi Anodes Toward Diffusion‐Controlled Reaction for K‐Ion Batteries
Authors: Zhang Jing , Kim Gilseob , Park Mihui , Zhang Jiliang , Lee Suwon , Cui Yingxue , Zhang Kai , Zou Feng , Kang Yong‐Mook 
Published: November 2022

AbstractNanostructuring is regarded as a significant method for improving the reversibility of alloying anodes for potassium‐ion batteries (PIBs). However, it is still unclear how nanostructuring suppresses the mechanical deterioration upon potassiation/depotassiation. In this study, by in situ X‐ray diffraction, a size‐dependent phase transformation mechanism in a nano‐Bi material (≈15 nm), which avoids the voltage plateau mutation of bulk‐Bi material (≈250 nm) caused by an incomplete and irreversible two‐phase reaction is revealed. The potassiation of nano‐Bi follows a stepwise solid‐solution pathway without any phase transitions under nonequilibrium conditions, circumventing the nucleation of a new phase. The distinctive transition pathway, dominated by the diffusion‐controlled reaction, is accompanied by fast ionic transport kinetics and homogeneous diffusion. As a result, particle fracture is inhibited by isotropic expansion stress, developing a route for stable potassium storage. By contrast, the two‐phase transformation of bulk‐Bi is governed by an interface‐controlled reaction under equilibrium conditions with slow and heterogeneous diffusion, leading to a rapid capacity decay from anisotropic expansion. The comparison between equilibrium thermodynamic‐ and non‐equilibrium kinetic‐phase transformations uncovers the intrinsic mechanism explanatory of the mechanical robustness of the size‐reduced alloying anodes, and also emphasizes that solid‐state diffusion must be improved to attain highly fast kinetics with PIBs.
Broad diversity in monoterpene–sesquiterpene balance across wild sunflowers: Implications of leaf and floral volatiles for biotic interactions
Authors: Bahmani Keivan , Robinson Anestacia , Majumder Sambadi , LaVardera Angelina , Dowell Jordan A. , Goolsby Eric W. , Mason Chase M. 
Published: November 2022

AbstractPremiseAs plant lineages diversify across environmental gradients, species are predicted to encounter divergent biotic pressures. This study investigated the evolution of volatile secondary metabolism across species ofHelianthus.MethodsLeaves and petals of 40 species of wildHelianthuswere analyzed via gas chromatography–mass spectrometry to determine volatile secondary metabolite profiles.ResultsAcross all species, 500 compounds were identified; 40% were sesquiterpenes, 18% monoterpenes, 3% diterpenes, 4% fatty acid derivatives, and 35% other compounds such as phenolics and small organic molecules. Qualitatively, annuals and species from more arid western climates had leaf compositions with a higher proportion of total monoterpenes, while erect perennials and species from more mesic eastern habitats contained a higher proportion of total sesquiterpenes. Among species, mass‐based leaf monoterpene and sesquiterpene abundance were identified as largely orthogonal axes of variation by principal component analysis. Profiles for leaves were not strongly correlated with those of petals.ConclusionsVolatile metabolites were highly diverse among wildHelianthus, indicating the value of this genus as a model system and rich genetic resource. The independence of leaf and petal volatile profiles indicates a low level of phenotypic integration between vegetative and reproductive structures, implying vegetative defense and reproductive defense or pollinator attraction functions mediated by terpene profiles in these two organs can evolve without major trade‐offs. The major biosynthetic pathways for the major terpenes in wildHelianthusare already well described, providing a road map to deeper inquiry into the drivers of this diversity.
AgOTf/Et3N Cooperative Catalysis Enabled One‐Pot Access to α‐(Indolizinylethyl)‐Substituted N‐Sulfonyl Ketimines via an Imino‐Alkyne Cyclization
Authors: Lodhi Rajni , Patel Ashvani K. , Samanta Sampak 
Published: November 2022

AbstractThe β‐Csp3−H functionalization of N‐sulfonyl ketimines with 2‐(2‐enynl)pyridines/quinolines via a cooperative Ag(I)‐/organobase‐catalyzed 5‐endo‐dig cyclization‐addition reaction is reported. This successive C−N/C−C bond‐making reaction provides a simple and atom‐economical technique for granting a diverse set of 1,3‐disubstituted indolizines/pyrrolo[1,2‐a]quinolines possessing a synthetically resourceful N‐sulfonyl ketimine moiety. Moreover, our designed strategy applies to broad substrates and allows various functionalities. Furthermore, this technique has many imperative synthetic points such as mild reaction conditions, low catalyst loading, acceptable chemical yields and highly diastereoselective (up to ≤93 : 7 dr). The N‐sulfonyl ketimine moiety of indolizine was easily transmuted into the reputed classes of coumarin and benzofuran derivatives.