bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of RESET care program: A real-world-evidence on managing non-alcoholic fatty liver disease through digital health interventions
Authors: Soni Jayesh , Pathak Nikhilesh , Gharia Mihir , Aswal Devina , Parikh Jaymin , Sharma Prachi , Mishra Astha , Lalan Dhvni , Maheshwari Twinkle 
Published: January 2025

BACKGROUND
Non-alcoholic fatty liver disease (NAFLD) management requires sustainable lifestyle modifications. This study aimed to evaluate the effectiveness of the RESET care plan, a comprehensive program that is an integrated personalized diet, exercise, and cognitive behavior therapy, delivered via MyTatva’s digital health application enabled through a body composition analyzer (BCA) and smartwatch.
AIM
To evaluates the effectiveness of the comprehensive program delivered via MyTatva’s digital health app enabled through internet of thing devices.
METHODS
This retrospective observational study analyzed deidentified data from 22 participants enrolled in the MyTatva RESET care program. Participants were divided into three groups: Group A, diet plan; Group B, diet + exercise plan; and Group C, diet + exercise + cognitive behavioral therapy plan. Participants were provided with a BCA and smartwatch for continuous monitoring of anthropometric parameters. Statistical analysis, including one-way ANOVA and post-hoc Tukey’s Honest Significant Difference test, was conducted to compare mean changes in anthropometric parameters across the groups.
RESULTS
All intervention groups showed significant improvement across all anthropometric parameters. Group C showed the most significant improvements, with mean weight reduction of 7% or more (6.99 ± 2.98 kg, 7.00% ± 3.39%; P = 0.002) from baseline, a benchmark associated with improved NAFLD conditions. Post-hoc analysis revealed that Group C had significantly greater improvements than Groups A and B. Weight reduction was observed in 85.7% of Group A participants, 77.8% of Group B participants, and 100% of Group C participants.
CONCLUSION
The comprehensive RESET care plan achieved a 7% weight reduction in 12 weeks, demonstrating its effectiveness in managing NAFLD. These results support adopting digitally supported, patient-centric approaches for NAFLD treatment.
Hepatic eosinophilic pseudotumor due to Fasciola hepatica infection mimicking intrahepatic cholangiocarcinoma: A case report
Authors: Le Kim-Long , Tran Minh-Quang , Pham Tri-Nhan , Duong Nhu Ngoc-Quynh , Dinh Thien Thuan , Le Nguyen-Khoi 
Published: January 2025

BACKGROUND
Hepatic eosinophilic pseudotumor (HEPT) is a rare condition that mimics malignant hepatic tumors, posing significant diagnostic challenges. This case report highlights the importance of considering parasitic infections like Fasciola hepatica (F. hepatica ) in the differential diagnosis of hepatic masses, especially in endemic regions, to prevent unnecessary interventions.
CASE SUMMARY
A 40-year-old female presented with a 1-month history of epigastric pain and significant weight loss. Imaging revealed a hepatic mass, initially misdiagnosed as intrahepatic cholangiocarcinoma. Laboratory results showed marked eosinophilia, and histopathological examination confirmed significant eosinophilic infiltration without malignancy. Serological testing identified F. hepatica infection. The patient was treated with a single dose of triclabendazole, leading to complete symptom resolution and normalization of hepatic imaging findings within days.
CONCLUSION
HEPT due to F. hepatica can closely mimic malignancy; timely antiparasitic treatment is crucial for resolution.
Impact of liver cirrhosis on morbidity and mortality of patients admitted to the hospital with necrotizing fasciitis
Authors: El Labban Mohamad , Kotys Juliet , Makher Sabrina , Pannala Sai Shanmukha Sreeram , El Gharib Khalil , Chehab Hamed , Deeb Liliane , Surani Salim R 
Published: January 2025

BACKGROUND
Necrotizing fasciitis (NF) is a potentially fatal bacterial infection of the soft tissues. Liver cirrhosis appears to be a contributing factor to higher morbidity and mortality in patients with NF. This research article explores the relationship between these two conditions.
AIM
To evaluate whether liver cirrhosis increases morbidity and mortality in patients with NF, focusing on inpatient mortality, septic shock, length of stay, and hospital costs.
METHODS
This retrospective cohort study utilized data from the Healthcare Cost and Utilization Project 2019 National Inpatient Sample. Cases were identified as patients with both NF and cirrhosis, while controls were non-cirrhotic. The study focused on inpatient mortality as the primary outcome, with secondary outcomes including surgical limb amputation, mechanical ventilation rates, septic shock, length of stay, and hospital costs.
RESULTS
A total of 14920 patients were admitted to the hospital for management of NF, of which 2.11% had liver cirrhosis. Inpatient mortality was higher in cirrhotic patients (9.5% vs 3%; adjusted odds ratio = 3.78; P value = 0.02). Cirrhotic patients also had higher rates of septic shock (10.5% vs 4.9%, P value < 0.01). Length of hospital stay, total charges, and rates of mechanical ventilation were not statistically different between groups.
CONCLUSION
Liver cirrhosis is an independent risk factor of in-hospital mortality and morbidity in patients with NF. Clinicians should be aware of this association to ensure better clinical outcomes and spare healthcare expenditure.
Hotspots and trends in stem cell therapy for liver fibrosis and cirrhosis: A bibliometric analysis
Authors: Zhu Wen-Yan , Li Xiang , Xie Jia-Ling , Lu Qin , Ma Ying-Jie , Zhu Zhao-Jing , Liu Juan 
Published: January 2025

BACKGROUND
Liver fibrosis and cirrhosis are global medical challenges that require safe and effective treatments. In the past two decades, there has been a surge in research on stem cell therapy for liver fibrosis and cirrhosis. This study aimed to conduct a comprehensive analysis of the research hotspots and trends in this field through bibliometrics.
AIM
To conduct a bibliometric analysis on hotspots and trends in stem cell therapy for treatment of liver fibrosis and cirrhosis.
METHODS
Publications on stem cell therapy for liver fibrosis and cirrhosis were retrieved from the Web of Science Core Collection database. The distribution and collaboration among literature, authors, countries, and institutions were analyzed visually using Excel, CiteSpace, Bibliometrix R-package, VOSviewer and Pajek software. Additionally, an investigation of keywords, burst keywords, and clusters was conducted.
RESULTS
As of September 20, 2024, a total of 1935 documents were retrieved dating from 2004 to 2024, with 1186 strongly relevant publications obtained after screening. China, the United States, and Japan were the major contributors in this field. Cairo University, Zhejiang University and Yamaguchi University were the major institution in this field. The journal Stem Cell Research & Therapy published the most papers. There were 686 authors, with Shuji Terai, Isao Sakaida, Soon Koo Baik, and Lanjuan Li publishing the most papers. The research focused on alcoholic cirrhosis and nonalcoholic fatty liver disease. The emerging areas of interest were extracellular vesicles, exosomes, and their enriched microRNAs. The field is experiencing rapid growth due to the changing research trends and increasing literature.
CONCLUSION
These findings provide a thorough overview of stem cell therapy in the field of liver fibrosis and cirrhosis.
Fire Evaluation on Thermal Oxidizer (TOX) at XY Company with Fishbone Approach
Authors: Izagy Rif’at Bayu , Aprilia Dewinta Keysa , Ardhana Muhammad Jaggu , Hifdzia Naila , Akbar ramadhan Raihan 
Published: January 2025

On April 9, 2020, Thermal Oxidizer (TOX) at PT. XY burned. Its function is to control exhaust emissions by burning harmful organic compounds. In this case, the Waste Heat Recovery Unit (WHRU) located above the TOX combustion chamber failed. Gas Turbine Generators (GTG) failed. This study uses a fishbone diagram approach to identify the cause of the fire. Maintenance policies, machine errors, human error, extreme environmental conditions, and inadequate operational procedures are some of the causes. The results of the analysis show that improving workers' operational skills, regular equipment inspections, and improving safety management systems are essential. These results provide practical advice to improve operational safety and prevent similar incidents in the future
A Comparative Study on Knowledge and Attitude related to COVID-19 disease among general public residing in selected Urban and Rural areas
Authors: Bhosale Swapnil , Nirmal Nitin , Kadu Amit 
Published: January 2025

Introduction: COVID-19 is an emerging respiratory infection that was first discovered in December 2019, in Wuhan city, Hubei Province, China SARS-CoV-2 belongs to the larger family of ribonucleic acid (RNA) viruses, leading to infections, from the common cold, to more serious diseases, such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). The main symptoms of COVID-19 have been identified as fever, dry cough, fatigue, myalgia, shortness of breath, and dyspnoea. COVID-19 is characterized by rapid transmission, and can occur by close contact with an infected person. The details on the disease are evolving, by the end of January 2020, the World Health Organization (WHO) announced a public health emergency of international concern and called for the collaborative effort of all countries, to prevent its rapid spread. The aimed of the study was to determine the knowledge, attitude and practices related to Covid-19 among urban and rural population. Methodology: The study was conducted at selected urban and rural areas, by using Descriptive survey research design. Total 200 samples were selected by using non probability convenient sampling technique. The population for the present study were general public residing in selected urban and rural area. Results: assessment of knowledge regarding COVID-19, shows that 63% population in rural area had poor average knowledge and 89% had average knowledge about it. The 89% rural people had unfavorable attitude about covid 19, and 59% had neutral attitude seen in urban population. Conclusion: Result of level of knowledge and attitude regarding Covid-19 shows that urban people had good knowledge and attitude regarding COVID-19 than rural people.
The Effectiveness of EMG Biofeedback to Improve Ankle Dorsiflexion in Stroke Patients: A Systematic Review
Authors: Toshniwal Dr. Gaurav , Ganvir Dr. Suvarna S. , Harishchandre Dr. Maheshwari 
Published: January 2025

Background: Stroke, results in some form of residual deficits even after recovery. Patients face difficulty in ambulating, probably because of reduced ankle dorsiflexion. Present systematic review aims to explore the literature-related to studies conducted on patients with Stroke for the effectiveness of electromyography biofeedback (EMG BF) therapy in the treatment of ankle dorsiflexion. Methodology: This study included nine randomised trials, all including patients who developed stroke after an episode of acute Ischemic infract. Use of databases Google Scholar, PubMed and CINHAL full text was done. Results: EMG muscle activity also showed improvement in 3 out of 9 studies. This may be attributed to gradual weight bearing and improving in muscle activity over the period of time. Discussion: EMG BF is useful for improving motor functions and walking speed as well as increasing ROM and muscle activation maybe because new pathways are formed or previous cerebral and spinal pathways and networks are activated by the stimulation with feedback or remaining proprioceptive senses are regulated by visual and acoustic warnings. Conclusion: There is gradual weight bearing and improvement in muscle activity post EMG BFB over the period of time.
Strategi Ekspansi Mixue di Pasar Indonesia menggunakan Pendekatan Teoritis Simon dan Mintzberg
Authors: Hidayat N Rusdi , Kusumasari Indah Respati , Akbar Galang Falah , Ramadhan Baraa Ziyad , Arfian Zeta 
Published: January 2025

Mixue, merek es krim dan minuman teh asal Tiongkok, telah mencatat pertumbuhan yang signifikan di Indonesia sejak memasuki pasar pada tahun 2020 dengan membuka lebih dari 300 gerai hingga akhir 2022. Penelitian ini bertujuan untuk menganalisis strategi ekspansi Mixue menggunakan pendekatan bounded rationality dari Herbert Simon dan teori 5 P’s of Strategy dari Henry Mintzberg. Teori bounded rationality menjelaskan pengambilan keputusan Mixue yang didasarkan pada informasi terbatas namun relevan, seperti dalam penentuan lokasi gerai dan seleksi mitra waralaba. Sementara itu, teori 5 P’s of Strategy memberikan kerangka kerja untuk mengevaluasi strategi Mixue melalui elemen Plan, Ploy, Pattern, Position, dan Perspective. Penelitian ini juga menemukan bahwa efisiensi rantai pasok yang terintegrasi dan model bisnis waralaba memberikan kontribusi signifikan terhadap percepatan ekspansi Mixue. Efisiensi rantai pasok memungkinkan Mixue menyediakan produk berkualitas dengan harga terjangkau, sementara model waralaba mempercepat pembukaan gerai baru melalui kolaborasi dengan mitra lokal. Pendekatan pemasaran digital berbasis media sosial, seperti kolaborasi dengan influencer, meningkatkan brand awareness dan keterikatan emosional dengan konsumen. Pendekatan glokalisasi Mixue, seperti menyesuaikan produk dengan selera lokal tanpa menghilangkan identitas merek, juga memperkuat daya tariknya di pasar Indonesia. Hasil penelitian menunjukkan bahwa penerapan strategi berbasis teori Simon dan Mintzberg memungkinkan Mixue untuk mengembangkan langkah-langkah adaptif dan responsif terhadap dinamika pasar Indonesia yang kompetitif. Keberhasilan ini memberikan implikasi bagi perusahaan ritel lain yang ingin memperluas operasinya di pasar serupa.
Kendala Pada Implementasi Adat Basandi Syarak’Syarak Basandi Kitabullah di Nagari Painan Timur
Authors: Azarah Sakinah , Malau Hasbullah 
Published: January 2025

Tujuan dari Penelitian ini mengungkapkan hambatan dalam Implementasi Adat Basandi Syarak' Syarak Basandi Kitabullah pada Negeri Painan Timur. Penulis mengunakan pendekatan yang kualitatif menggunakan metode deskriptif.Teknik yg dipakai dalam penelitian yaitu purposive sampling.Pada Teknik pengumpulan data memakai observasi, wawancara, dokumentasi, & triagulasi.Dalam penelitian ini penulis memakai Teknik analisis data yaitu pengumpulan data, reduksi data, penyajian data, & penarikan Kesimpulan.Hasil penelitian ini merupakan hambatan Implementasi dalam abs-sbk dicermati menurut beberapa pertarungan yaitu: a) Perkembangan Teknologi, b) Kurangnya nilai-nilai tata cara terhadap modernisasi.
Implementasi Kurikulum Merdeka pada Pembelajaran Pendidikan Agama Islam dalam Mengembangkan Kreativitas Peserta Didik di SMP Negeri 1 Leuwiliang Kabupaten Bogor
Authors: Ujang Supriadi  , Riyanto  , Yusi Srihartini  
Published: January 2025

The implementation of the independent curriculum is a concept that is preferred in the world of education because it requires educators to show creativity in the learning process while allowing students to explore their potential and foster creativity, innovation, and independence. As with the new discourse, there are of course pros and cons to consider. Education serves as a means to form and achieve personal goals. Educational guidance must be derived from the Qur'an, because the Qur'an consistently provides instructional cues as a whole, from the opening verse to the closing verse. Through obedience to the values embraced in the Qur'an, individuals can be guided towards creativity, dynamism, and the achievement of the essential values of ubudiyah in relation to their creator. This research is a descriptive qualitativeresearch. Data collection techniques use observation, interviews, and documentation. The data obtained was analyzed using three stages, namely: 1) Data reduction, 2) Data presentation, 3) Drawing conclusions and verification. The data validity techniques used were: The sources observed were, Islamic Religious Education Teachers, Principals, Curriculum Officers, and Students at SMPN 1 Leuwiliang, Bogor Regency. The results of this study show that the implementation of the learning process of the application of the independent curriculum in Islamic Religious Education at SMPN 1 Leuwiliang, Bogor Regency has been carried out through the implementation of summative assessments at the end of the odd semester of the 2023/2024 school year. These assessments combine different approaches, starting with face-to-face teaching during the post-pandemic era.several learning models are introduced, project-based learning models, problem-based learning models, discovery learning models, and inquiry learning. The application of differentiated learning as a form of independent curriculum has resulted in a positive transformation in the development of student learning creativity in Islamic religious education at SMPN 1 Leuwiliang, Bogor Regency. This is evidenced by the increase in students' abilities after the implementation of independent learning. critical thinking skills, emotional sensitivity, facilitating collaborative efforts in the completion of academic tasks, encouraging the dissemination of their work in social circles.
Accuracy of AI in Cyber Security: Navigating the Dual-Edged Dynamics of an Evolving Security Frontier
Authors: Sanka Sreekrishna , Gochhayat Dr. Sarada Prasad , Torremoch Virgil , Kethar Jyotsna 
Published: January 2025

In the rapidly evolving domain of cyber security, the advent of AI (AI) and ML (ML) has marked a paradigmatic shift, enhancing the accuracy and efficiency of identifying and mitigating vulnerabilities. This paper delves into the dual-edged dynamics of AI in cyber security, examining the historical trajectory from manual identification methods to AI-driven approaches. While AI and ML have significantly improved the Accuracy and timeliness that accelerated the detection and analysis of cyber threats, offering predictive insights and adaptive defenses, they also introduce new challenges, including ethical considerations, transparency issues, and the potential for adversarial manipulations. The integration of Generative AI and Large Language Models (LLMs) further complicates the security landscape, presenting both novel opportunities and vulnerabilities. This paper emphasizes the critical role of responsible AI and governance in navigating these complexities, advocating for a balanced approach that leverages AI's strengths while addressing its limitations. As cyber security continues to adapt to these technological advancements, fostering innovation while ensuring ethical and transparent practices remains paramount. Significant findings from the study reveal that the integration of AI (AI), Large Language Models (LLMs), and Generative AI has markedly enhanced both accuracy and timeliness in cyber security operations. This advancement facilitates the early detection of threats and vulnerabilities, thereby substantially improving preventative measures. Furthermore, Generative AI and LLMs have pioneered innovative pathways for Threat Modeling techniques, revolutionizing the approach to threat prevention. Both Cyber Security Specialists and Hackers use these advances to improve upon each other continue this evolving trend.
Root Cause Analysis of Adverse Outcomes in the Obstetrics & Gynaecology: A Prospective Study at a Tertiary Care Centre
Authors: Narayan Brijesh , Mendiratta Pushkar 
Published: January 2025

Abstract

Background
: Adverse events are an unwanted outcome in the routine course of patient management, with an adverse event in Obstetrics assuming even greater importance because of the extended implications for the newborn. There is limited data available on the adverse event emanating from Obstetrics and Gynaecology care in Indian population. Materials and
Methods: This prospective observational study which included all the consecutive inpatients admitted with the department of Obstetrics and Gynaecology over a period of 15 months at a tertiary care centre. Incidence of adverse events were noted. Root cause analysis of the events was done and contributory factors brought out were addressed. Results: The incidence of the adverse events in our study was 2.57 % (n=90) in a total of 3503 consecutive inpatients. The most common adverse event noted in our study was surgical site infection followed by birth asphyxia. The average duration of detection of adverse event was 8.5 days, with adverse event detected in 73% patients during admission. Out of these, 98.48% had a prolonged hospital stay which averaged 5.5 days. 58% of the adverse events were grade 3 in severity while 91.1% were deemed preventable. Conclusion: Adverse events carry a giant burden with them, but their incidence can definitely be cut down by adhering to institutional protocols, checklists, increased awareness and involvement at multiple levels of hierarchy.
Cierre de fistula esófago-yeyunal post operatoria con clips endoscópicos de titanio y over-the-scope clip: reporte de caso
Authors: Arango Molano Lázaro , Sánchez Gil Andrés , Núñez Rojas Gian , Solarte Pineda Herney , Salazar Ochoa Santiago 
Published: January 2025

Las fístulas de las anastomosis esófago-yeyunales postquirúrgicas pueden llegar a ser mortales. En la actualidad existe un amplio arsenal de medidas terapéuticas que van desde el manejo conservador, la terapia endoscópica, hasta la cirugía de revisión. El manejo endoscópico se ha posicionado por encima de las demás estrategias debido a la mínima invasión, lo que mejora la sobrevida y disminuye la mortalidad. El tratamiento endoscópico de las fístulas esófago-yeyunales puede ser variado con numerosas técnicas descritas para lograr el cierre de estas. Dentro de estas técnicas destacan la colocación de stents autoexpandibles recubiertos o parcialmente cubiertos, el uso de clips metálicos, solos o ayudados por la técnica del loop, el uso de la terapia de presión subatmosférica cerrada endoscópica (e-VAC) y, más recientemente, el uso de sutura endoscópica. En nuestro servicio usamos las técnicas nombradas de acuerdo a las características de la fístula. En el caso presentado se decidió, en el momento mismo de la endoscopia, el uso de clips con la ayuda de un Cap para facilitar la técnica y en el ángulo terminal de cierre, ante el tejido redundante de difícil aproximación, optamos por poner un clip tipo Padlock®; con esto se logró el cierre de la lesión en pocos días y una excelente evolución del paciente.