bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel approach to partial coverage in wireless sensor networks via the roman dominating set
Authors: Ghaffari Fatemeh , Bahrak Behnam , Shariatpanahi Seyed P. 
Published: February 2022

AbstractOne major challenge in deploying wireless sensor networks (WSN) in real‐world applications is minimising the energy consumption by the sensors while maintaining the coverage of the monitored field. However, many applications do not need full coverage of the monitored area all the time, which can help us reduce the network's energy consumption. One approach to exploit this property is to set up a sleep/wake‐up schedule for each node such that no redundant nodes are active in an area of coverage simultaneously. This will allow the existence of monitoring holes in a controlled manner, which the authors call partial coverage. In this study, the partial coverage condition is imposed by constructing a Roman Dominating Set of awake nodes in the network. Roman domination is a method for colouring a graph's vertices with three labels (0, 1, 2), such that all the vertices with label 0 have an adjacent vertex with label 2, while the sum of the labels of nodes is minimised. Based on this formulation, a simple greedy algorithm is proposed to construct such a structure supported by three theorems. Furthermore, the performance of the authors’ proposal in different scenarios is evaluated.
Super‐resolution forward‐looking imaging method for manoeuvering platform with optimised dictionary and extended sparsity adaptive matching pursuit
Authors: Zhang Gang , Liang Yi , Chen Shuxuan , Xing Mengdao , Li Zhenfang 
Published: February 2022

AbstractIn forward‐looking imaging, left‐right Doppler is ambiguous and cross‐range resolution is limited by real aperture, which result in traditional synthetic aperture radar imaging methods no longer applicable. Besides, the impact of three‐dimensional acceleration on an over‐complete dictionary matrix and sparse reconstruction kernel is not considered in conventional super‐resolution forward‐looking imaging methods. To solve these problems, a super‐resolution forward‐looking imaging method for manoeuvering platforms is proposed. First, the range walk caused by forward‐looking geometry and higher‐order phase introduced by three‐dimensional acceleration are eliminated by compensating a pre‐processing function. Subsequently, according to beam steering‐based geometry and linear regression model, the over‐complete dictionary matrix is optimised to more accurately describe the complicated forward‐looking geometry with curved trajectory. Finally, sparsity adaptive matching pursuit kernel with an improved halting condition is adopted to reconstruct the forward‐looking scene. The proposed method is supported by point target simulation and surface target simulation.
Stellar activity correction using PCA decomposition of shells
Authors: Cretignier M. , Dumusque X. , Pepe F. 
Published: February 2022

Context.Stellar activity and instrumental signals are the main limitations to the detection of Earth-like planets using the radial-velocity (RV) technique. Recent studies show that the key to mitigating those perturbing effects might reside in analysing the spectra themselves, rather than the RV time series and a few activity proxies.Aims.The goal of this paper is to demonstrate that we can reach further improvement in RV precision by performing a principal component analysis (PCA) decomposition of the shell time series, with the shell as the projection of a spectrum onto the space-normalised flux versus flux gradient.Methods.By performing a PCA decomposition of shell time series, it is possible to obtain a basis of first-order spectral variations that are not related to Keplerian motion. The time coefficients associated with this basis can then be used to correct for non-Dopplerian signatures in RVs.Results.We applied this new method on the YARARA post-processed spectra time series of HD 10700 (τCeti) and HD 128621 (αCen B). On HD 10700, we demonstrate, thanks to planetary signal injections, that this new approach can successfully disentangle real Dopplerian signals from instrumental systematics. The application of this new methodology on HD 128621 shows that the strong stellar activity signal seen at the stellar rotational period and one-year aliases becomes insignificant in a periodogram analysis. The RV root mean square on the 5-yr data is reduced from 2.44 m s−1down to 1.73 m s−1. This new approach allows us to strongly mitigate stellar activity, however, noise injections tests indicate that rather high signal-to-noise ratio (S/N > 250) is required to correct for the observed activity signal on HD 128621.
The Planck clusters in the LOFAR sky
Authors: Botteon A. , Shimwell T. W. , Cassano R. , Cuciti V. , Zhang X. , Bruno L. , Camillini L. , Natale R. , Jones A. , Gastaldello F. , Simionescu A. , Rossetti M. , Akamatsu H. , van Weeren R. J. , Brunetti G. , Brüggen M. , Groeneveld C. , Hoang D. N. , Hardcastle M. J. , Ignesti A. , Di Gennaro G. , Bonafede A. , Drabent A. , Röttgering H. J. A. , Hoeft M. , de Gasperin F. 
Published: February 2022

Context. Relativistic electrons and magnetic fields permeate the intra-cluster medium (ICM) and manifest themselves as diffuse sources of synchrotron emission observable at radio wavelengths, namely radio halos and radio relics. Although there is broad consensus that the formation of these sources is connected to turbulence and shocks in the ICM, the details of the required particle acceleration, the strength and morphology of the magnetic field in the cluster volume, and the influence of other sources of high-energy particles are poorly known.
Aims. Sufficiently large samples of radio halos and relics, which would allow us to examine the variation among the source population and pinpoint their commonalities and differences, are still missing. At present, due to the physical properties of the sources and the capabilities of existing facilities, large numbers of these sources are easiest to detect at low radio frequencies, where they shine brightly.
Methods. We examined the low-frequency radio emission from all 309 clusters in the second catalog of Planck Sunyaev Zel’dovich detected sources that lie within the 5634 deg2 covered by the Second Data Release of the LOFAR Two-meter Sky Survey (LoTSS-DR2). We produced LOFAR images at different resolutions, with and without discrete sources subtracted, and created overlays with optical and X-ray images before classifying the diffuse sources in the ICM, guided by a decision tree.
Results. Overall, we found 83 clusters that host a radio halo and 26 that host one or more radio relics (including candidates). About half of them are new discoveries. The detection rate of clusters that host a radio halo and one or more relics in our sample is 30 ± 11% and 10 ± 6%, respectively. Extrapolating these numbers, we anticipate that once LoTSS covers the entire northern sky it will provide the detection of 251 ± 92 clusters that host a halo and 83 ± 50 clusters that host at least one relic from Planck clusters alone. All images and results produced in this work are publicly available via the project website.
Flexible diverticulotomy for Zenker's diverticulum – a bicentric study
Authors: Epping Hendrik , Ziachehabi Alexander , Spaun Georg , Wewalka Friedrich , Maieron Andreas , Schöfl Rainer 
Published: February 2022

Abstract
Introduction Flexible diverticulotomy is an established procedure for the treatment of Zenker's diverticulum. In a bicentric study, we investigated the development of the procedure since its introduction at the Ordensklinikum Linz Barmherzige Schwestern and Elisabethinen in 2010.
Methods All flexible diverticulotomies performed between January 2010 and December 2019 at the above-mentioned clinics were evaluated retrospectively. Patients were divided into two 5-year periods (2010–2014 and 2015–2019) and statistical tests were performed for comparison of data.
Results In all, 69 flexible diverticulotomies were performed. The procedure was technically successful in 93.5% of cases. No lethal outcome was encountered. Only 2 (2.9%) interventions led to serious complications which had to be treated in the intensive care unit. Mild complications occurred in 14.5% of cases. 54 patients were evaluated in the follow-up period; 11 (20.3%) patients experienced relapses of dysphagia. The primary intervention resulted in a significant improvement over the observation period. Patients in the second intervention group had shorter average hospital stays and longer recurrence-free intervals.
Conclusion Flexible diverticulotomy is a safe and effective procedure for the treatment of Zenker's diverticulum. However, as the success rate appears to depend on the expertise and experience of the department, flexible diverticulotomy should be performed at centers with high caseloads.
Pelvic Radiation Disease
Authors: Sammour Tarik , Kahokehr Arman A. 
Published: February 2022

AbstractPelvic radiation is increasingly being used for the neoadjuvant and definitive treatment of pelvic organ malignancy. While this treatment can be highly effective, and may assist in organ sparing, it is also associated with significant toxicity and devastating adverse events that need to be considered. In broad terms, pelvic radiation disease affects both the primary target organ as well as adjacent organs and soft tissue structures, with complications that can be classified and graded according to consensus criteria. The complication grade is often modality, dose, and area dependent. The most common manifestations are proctitis, cystitis, recto-urethral fistula, ureteric stricture, and bone involvement. Toxicity can be misdiagnosed for many years, resulting in significant management delays. Complications can be difficult to prevent and challenging to treat, requiring specialized multi-disciplinary input to achieve the best possible strategy to minimize impact and improve patient quality of life.
Real-World Experience with Nivolumab in Metastatic Renal Cell Carcinoma Patients Who Have Progressed on Prior Therapies: A Single-Center Study from India
Authors: Rauthan Amit , Murthy Nitin Yashas , Patil Poonam , Nigade Gaurav , Somashekhar SP , Zaveri Shabber S. 
Published: February 2022

Introduction Nivolumab monotherapy is approved for the treatment of metastatic renal cell carcinoma (mRCC) patients who have progressed on prior therapies based on the pivotal Checkmate-025 trial. There is limited literature on the efficacy and safety profile of usage of nivolumab in the treatment of mRCC in India in a real-world setting.
Methods A retrospective analysis was performed of patients who received nivolumab monotherapy for mRCC after having progressed on prior therapies. Tumor response was graded according to RECIST v1.1 and Kaplan–Meier survival analysis was used to estimate progression-free survival (PFS) and overall survival (OS). Immune-related adverse events (irAEs) were documented and graded according to CTCAE v5.0.
Results Between 2016 and 2019, 35 patients received nivolumab for mRCC at our center after progression on prior therapies. A majority of the patients (n = 30, 85.7%) received it in a second-line setting, and the remaining in the third line and beyond setting. Clear cell was the most common histology (n = 26, 74.3%). There were 18 patients (51.42%) who belonged to IMDC intermediate risk, while 17 (48.58%) patients were at poor risk. The overall response rate was 60%, with complete response (CR) in 11.4%. Median duration of response was not reached among responders. Median PFS was 5 months (95% confidence interval [CI]: 3.06–6.93) and median OS was 26 months (95% CI: 1.90–50.09). Ongoing survival of 47, 42, 34, and 22 months was noted in four patients with CR, respectively. In our study, 23 patients (65.71%) experienced any grade of irAE. Grade 3 irAEs was seen in four patients (11.42%). Most common irAE was thyroid dysfunction seen in 12 patients (34.2%). Treatment discontinuation due to irAEs occurred in three patients (8.57%).
Conclusion Nivolumab showed good efficacy with high response rates and an OS comparable to the pivotal Checkmate-025 trial. It was well tolerated with safety profile in terms of irAE consistent with those reported in literature.
Are we Missing Barrett's Esophagus in Our Busy Endoscopy Practice? Improving Detection
Authors: Dutta Amit Kumar 
Published: February 2022

AbstractBarrett's esophagus (BE) denotes the replacement of stratified squamous epithelium of esophagus by columnar epithelium. It is associated with a significantly increased risk of esophageal adenocarcinoma and hence patients with BE are advised endoscopic surveillance for early detection of dysplastic and neoplastic lesions. Esophageal cancer is the sixth most common cancer in terms of incidence and mortality in India. Around 15 to 25% of esophageal cancers are adenocarcinoma. BE is likely to be an important precursor of esophageal adenocarcinoma and we may be missing patients with BE in our busy endoscopy practice. The detection of BE may be improved by identifying high-risk groups, performing thorough endoscopic examination, and applying newer imaging techniques. The high-risk group includes patients with chronic gastroesophageal reflux disease, obesity, smoking, etc. During endoscopic examination, a careful assessment of the gastroesophageal junction and identification of important landmarks such as gastroesophageal junction and Z line are essential to detect BE. Management of BE depends on the detection of dysplasia and for this four quadrant mucosal biopsy is recommended every 1 to 2 cm. However, random biopsy samples only a small area of mucosa and advanced technologies for real-time detection of dysplasia and neoplasia may overcome this limitation. In this review, we discuss the current scenario of BE in India and ways to improve the detection of BE including dysplastic lesions.
Assessment of the CHIVA and the ASVAL Method
Authors: Recek Cestmir 
Published: February 2022

AbstractIn this article, the CHIVA and ASVAL methods are assessed from the hemodynamic point of view. The CHIVA method comprises complicated, unusual terminology and new perceptions, such as closed and open shunts, fractionation of the hydrostatic pressure, subdivision of the venous network. The principal part of the CHIVA theory is the drainage of venous blood from the thigh saphenous system into the deep lower leg veins through the preserved saphenous trunk after high ligation at the saphenofemoral junction, which is considered as a beneficial, physiological phenomenon. In reality, this is recurrent reflux producing ambulatory venous hypertension. The main impact of the CHIVA procedure is the elimination of the saphenous reflux by high ligation at the saphenofemoral junction; thus it can be presumed that the CHIVA procedure yields similar results like the crossectomy.The ASVAL procedure is de facto the modification of the old Madelung method that was the prevalent surgical procedure before the Trendelenburg era in the 19th century. The results after ASVAL were not checked by plethysmography; there is a good case to suppose that the results after the ASVAL method would comply with those after sclerotherapy.
A Pandemic of Webinars in the COVID Era—Can It be the Way Forward?
Authors: Thenmozhi Senthilvelan , Girija Subramanian , Viswanathan K. Neelakantan , Badrinath Aritakulu Kuppuswamy 
Published: February 2022

Abstract
Introduction Conferences are important and sometimes mandatory to update the clinician with latest knowledge. Attending conferences requires planning, expenditure, and leave from work. Webinars have become the new normal in the coronavirus disease (COVID) era. We surveyed the esteemed medical fraternity on their opinion on webinars.
Methods This was conducted as an online survey (Survey Monkey) through personal electronic mails and social media with 24 questions. Details on demographic profile, specialization and affiliation, experience, choice of frequency of webinar sessions, suitable platform, mode of intimation of webinars, number of days for prior intimation, appropriate timing of the day and week, and ideas on payment options were enquired. Need for technical assistance, choice of topic for discussions, methods to make webinars more interactive, availability of recorded content, and impact on clinical practice were also assessed.
Results A total of 235 medical professionals voiced their opinion; 67% were < 35 years of age and 49% were residents. An average of 2 to 3 webinars per month (33.8%), conducted on weekdays (63%), after 6 p.m. (54%) in the form of case discussion (67.3%) or lectures from experts (55%) with at least 7 days' notice (41.7%) was the most common choice; free webinars were the wish of 56.1% participants and 28% felt webinars would definitely impact practice.
Conclusion Webinars are welcoming even after the COVID era and should go hand-in-hand with conventional conferences. Virtual learning experience should be optimized by proper scheduling of multiple simultaneous events and converting them into interlinked or serial events.
Early-Term Results of Rapid-Deployment Aortic Valve Replacement versus Standard Bioprosthesis Implantation Combined with Coronary Artery Bypass Grafting
Authors: Taghiyev Zulfugar T. , Bechtel Matthias , Schlömicher Markus , Useini Dritan , Taghi Hamid Naraghi , Moustafine Vadim , Strauch Justus T. 
Published: February 2022

Abstract
Objectives Aortic stenosis is highly prevalent among patients with concomitant coronary artery disease. Surgical aortic valve replacement with coronary artery bypass grafting is usually the treatment of choice for patients with severe aortic stenosis and significant coronary disease. The aim of this study was to evaluate the outcome and hemodynamic results of the implantation of rapid-deployment valves (Rapid-Deployment Edwards Intuity Valve System [RDAVR]) versus conventional sutured valves (CSAVR) in combined surgery.
Methods Between January 2012 and January 2017, 120 patients underwent replacement via RDAVR and 133 patients underwent replacement using CSAVR with concomitant coronary bypass grafting. Clinical and echocardiographic data were compared.
Results The mean age was 76 ± 7 for RDAVR patients and 74 ± 6 years for CSAVR patients (p = 0.054); 48% in the RDAVR group were female versus 17% in the CSAVR group (p <0.002). Other characteristics such as diabetes mellitus, body-mass index, chronic obstructive pulmonary disease, nicotine consumption, and extracardiac arteriopathy were similar. Coronary three-vessel disease was more common in the RDAVR group (42.5 vs. 27.8%, p = 0.017). Both mean EuroSCORE II (6.6 ± 5.4 vs. 4.3 ± 3.0, p = 0.001) and STS score (5.4 ± 4.4 vs. 3.4 ± 2.4, p = 0.001) were significantly higher in the RDAVR group. Mean cross-clamp time (82 ± 25 vs. 100 ± 30 minutes, p < 0.001) and cardiopulmonary bypass time (119 ± 38 vs. 147 ± 53 minutes, p < 0.001) were shorter with RDAVR. The mean number of bypass grafts, length of hospital and ICU stays, and mechanical ventilation time were not statistically significant different. Hospital mortality was 2.5% for RDAVR and 9.7% for CSAVR (p = 0.019). There was a similar rate of stroke (5.8 vs. 6.0%, p = 0.990) and postoperative delirium (14.1 vs. 15.8%, p = 0.728). Mean gradients were 8.2 ± 4.1 mm Hg in the RDAVR group vs. 11.3 ± 4.6 mm Hg in the CSAVR group (p = 0.001) at discharge.
Conclusion RDAVR combined with coronary artery bypass grafting (CABG) can be performed extremely safely. Cross-clamp and cardiopulmonary bypass times can be significantly reduced with rapid deployment aortic valve system in the scenario of combined CABG. RDAVR resulted in lower gradients than CSAVR in patients implanted with prostheses of the same size.
Casting light on citizens’ conceptions of what is ‘political’
Authors: Görtz Carl , Zorell Carolin V. , Fitzgerald Jennifer 
Published: February 2022

AbstractExisting studies suggest that what people do and do not think of as being ‘politics’, varies a lot. Some citizens embrace narrow understandings, regarding only few issues as ‘political’. While others hold broad conceptions. What remains unclear is to what extent citizens agree on the contents, i.e., which topics are ‘political’. Using representative survey data from the U.S. (N = 1000), this article illustrates the overlaps and differences in conceptions of politics that different groups of citizens hold. Specifically, the results of a cluster analysis reveal five groups. The citizens within each group share similar conceptions of politics, while across groups conceptions differ. We find one group considering everything as political, one not regarding anything as such, and a third one identifying only tax-cuts as ‘political’. In between these extremes, two groups identify politics in terms of rather demarcated spheres of issues: domestic, or cross-border/global issues. Further analyses point to important differences in the groups’ socio-demographic profiles, political interest, and political behaviors. This shows, in their minds, people draw boundaries around politics in quite varied, yet principled, ways. This comes with a meaningful diversity in citizens’ connection to the political world around them, and with important implications for their roles within it.
Relational Sociology and Comparative Law
Authors: Conti Joseph A 
Published: February 2022

Abstract
Relational sociology, or the idea that relationships are the starting point for empirical research, offers comparative law distinctive analytical frameworks, heuristics, and methods. This Article proposes that these could advance traditional goals of comparative law by reconceiving fundamental categories of law, state, and society in relational terms while broadening the scope of useful comparison, and adopting a processual view of legal communities, legal knowledge, and culture rooted in practical action. It also highlights how comparative law offers sociology opportunities for deeper engagement with law, culture, transnationalism, and the dynamics of different normative orders. A relational analysis of disciplinary knowledge production suggests that deeper cross-disciplinary engagement has been limited less by shared interests than by the structures of academic knowledge production.
A nonproteinogenic amino acid, β-tyrosine, accumulates in young rice leaves via long-distance phloem transport from mature leaves
Authors: Sakamoto Shunta , Yoshikawa Takanori , Teraishi Masayoshi , Yoshinaga Naoko , Ochiai Kumiko , Kobayashi Masaru , Schmelz Eric A , Okumoto Yutaka , Mori Naoki 
Published: February 2022

ABSTRACT
Oryza sativa L. ssp. japonica cv. Nipponbare produces a nonproteinogenic amino acid (3R)-β-tyrosine from l-tyrosine by tyrosine aminomutase (OsTAM1). However, physiological and ecological function(s) of β-tyrosine have remained obscure. Often an improved understanding of metabolite localization and transport can aid in design of experiments to test physiological functions. In the current study, we investigated the distribution pattern of β-tyrosine in rice seedlings and found that β-tyrosine is most abundant in the youngest leaves. Based upon observations of high TAM1 activity in mature leaves, we hypothesized that β-tyrosine is transported from mature leaves to young leaves. Patterns of predominant mature synthesis and young leaf accumulation were supported by stable isotope studies using labeled β-tyrosine and the removal of mature leaves. Stem exudate analyses was also consistent with β-tyrosine transport through phloem. Thus, we identify young leaves as a key target in efforts to understand the biological function(s) of β-tyrosine in rice.