bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hidden Decomposers: the Role of Bacteria and Fungi in Recently Intermittent Alpine Streams Functional Processes
Authors: Gruppuso Laura , Receveur J. , Fenoglio S. , Bona F. , Benbow Mark Eric 
Published: July 2022

Abstract
The frequency of flow-intermittency and drying events in Alpine rivers is expected to increase due to climate change. These events can have significant consequences for stream ecological communities, though the effects of reduced flow conditions on the microbial communities of decomposing allochthonous leaf material require additional investigation. In this study, we investigated the bacterial and fungal communities associated with the decomposition of two common species of leaf litter, chestnut (Castanea sativa) and oak (Quercus robur). Sampling of experimentally placed leaf bags was spread over six collection points (up to 126 days after placement) at seven sites in the Western Italian Alps, which have historically differed in streamflow conditions. Bacterial and fungal communities from these leaf bags were identified using high-throughput amplicon sequencing. Chestnut and oak leaf bags harbored distinct bacterial and fungal communities, with a number of taxonomic groups differing in abundance, though bacterial communities began to converge at later sampling dates. Historical flow conditions (intermittent vs perennial rivers) and observed conditions (normal flow, low flow, ongoing drying event) had comparatively weak observed effects on bacterial and fungal communities to that of leaf type and collection date (i.e. length of decomposition). Our findings highlight the importance of leaf characteristics (e.g., C:N ratios, recalcitrance, etc.) to the in-stream conditioning of leaf litter and the need for additional investigations of drying events in Alpine streams. This study provides new information on the microbial role in leaf litter decomposition with expected flow changes associated with a global change scenario.
Improved Buck-boost Power Converter of SRG Drive
Authors: Zhu Yinyi , Chen Yan , Sun Haitao , Shao Mingzhi , Wang Ruihao , Zhao Zhenyu 
Published: July 2022

Abstract
In this paper, a novel improved buck-boost power converter is proposed to improve the performance of SRG system. This new power converter originated from a conventional buck-boost converter. In the proposed converter, a buck-boost part and additional switches form a buck-boost energy conversion stage. With this energy conversion stage, it is flexible to significantly boost the magnetization voltage and demagnetization voltage thereby improving output power range and reducing power loss. Firstly, the basic structure of the proposed converter is presented and its several operating modes are analyzed. Then the control strategy of the SRG system is made to control the output voltage and the boost capacitor voltage. In the end, the simulation results on a three-phase 12/8 SRG drive demonstrate the eligibility of the proposed power converter and the feasibility of the control scheme. Compared to the conventional buck-boost converter, this improved buck-boost converter accelerates the excitation process and reduces the power loss.
A parallel ADMM-based convex clustering method
Authors: Fodor Lidija , Jakovetić Dušan , Krstićev Danijela Boberić , Škrbić Srđan 
Published: July 2022

Abstract
Convex clustering has received recently an increased interest as a valuable method for unsupervised learning. Unlike conventional clustering methods such as k-means, its formulation corresponds to solving a convex optimization problem, and hence alleviates initialization and local minima problems. However, while several algorithms have been proposed to solve convex clustering formulations, including those based on the alternating direction method of multipliers (ADMM), there is currently a limited body of work on developing scalable parallel and distributed algorithms and solvers for convex clustering. In this paper, we develop a parallel, ADMM-based method for convex clustering for master-worker architectures, where the data to be clustered is partitioned across a number of worker nodes, and we provide its efficient, open-source implementation (available on [1]) for high performance computing (HPC) cluster environments. Extensive numerical evaluations on real and synthetic data sets demonstrate a high degree of scalability and efficiency of the method, when compared with existing alternative solvers for convex clustering.
Trees along a highway: Species composition, risk rating, and tree performance
Authors: Him Louis LEE Shing , ZHANG Hao , Kwun Kathy NG Tze , LO Shun Cheong , Lun Alan YU Siu 
Published: July 2022

Abstract
Species composition is an important aspect of urban forestry. Some urban tree stands may be monospecific. It is important to identify factors explaining and predicting the occurrence of monospecific stands in previous less-explored space, such as transport land use. A large-scale tree survey was conducted, covering 53 slopes and 52 verges along San Tin Highway in Hong Kong. The aim of this study was to examine the occurrence of monospecific stands in relation to the biodiversity and the structure of urban forests adjacent to transport routes. 7,209 trees were found in the surveyed sites. However, the tree stock was dominated by Corymbia citriodora (72%) which was featured in monospecific tree stands, especially for the highway verges. Using chi-square tests, significant associations were found between monospecific stands, habitat type, and tree risk rating. A logistic regression model was constructed to predict the occurrence of monoculture. Every metre increase in maximum tree height, the odds of a stand being monospecific would be 1.22 times greater. Stands on verges had 5.26 times greater odds of being monospecific against slope. The associations and relationships were attributed to the dominance of C. citriodora. By boosting the logistic model, model reliability increased as kappa rose from 0.51 to 0.63, while balanced accuracy improved from 0.72 to 0.85. The occurrence of monospecific stands could be reliably predicted using maximum tree height and habitat type of tree stands. The findings could assist urban forest management in terms of species selection and biodiversity enhancement.
The patterns and distribution of female genital tuberculosis among Togolese patients
Authors: Djiwa Toukilnan , Simgban Panakinao , Bombonne Mayi , Sama Bagassam Mézéwè , Douaguibe Baguilane , Tchaou Mazamaesso , Aboubakari Abdoul-Samadou , Darré Tchin 
Published: July 2022

Abstract
Objectives: Tuberculosis is a real public health problem in developing countries. The aim of our article was to study the epidemiological, clinical, diagnostic characteristics of female genital tuberculosis in Togo.Patients and methods: This was a descriptive and cross-sectional study on all cases concerning histologically diagnosed female genital tuberculosis in the department of pathological anatomy of Lomé in 1997-2018 (20years). Results: We collected 22 cases of women's GT, representing 2.2% (1008 cases) of extra-pulmonary tuberculosis. The mean age of the patients was 33.8 ± 0.2 years. Nine (9) patients had a history of treated GT. Depending on the location, the ovaries and fallopian tubes were the most affected (n=9 cases, 40.9%). Eighteen patients (81.8%) had at least one immunosuppression factor including HIV in 13 patients (72.2%). The reasons for consultation were metrorrhagia and pelvic pain with an associated mass in 7 women discovered on clinical examination and imaging. The macroscopic appearance of the specimens was suggestive of the diagnosis of genital tuberculosis in 12 cases (54.5%). Histology revealed caseous necrosis isolated in 3 patients (13.6%) and associated with gigantocellular epithelioid granulomas in 19 patients (86.4%). The patients received standard antibiotic treatment combining rifampicin, isoniazid, ethambutol and pyrazinamide. Conclusion: Genital tuberculosis is a rare extra-pulmonary location in Togo, often occurring in women with HIV, and the clinical polymorphism can lead to confusion with gynecological cancers.
Structured Inverted-File k-Means Clustering for High-Dimensional Sparse Data
Authors: Aoyama Kazuo , Saito Kazumi 
Published: July 2022

Abstract
This paper presents an architecture-friendly k-means clustering algorithm referred to as SIVF for a large-scale and high-dimensional sparse data set. Algorithm efficiency on time is often measured by the number of costly operations such as similarity calculations. In practice, it depends greatly on how an algorithm adapts to an architecture of the computer system which the algorithm is executed on. Our proposed SIVF is carefully designed so as to operate at high speed and suppress memory usage on modern CPU architectures. It exploits a structured inverted-file for a mean set with an invariant centroid-pair based filter (ICP) to decrease the number of similarity calculations in an architecture-friendly manner. The structured inverted-file with the ICP effectively reduce instructions as well as similarity calculations, suppressing pipeline hazards that may cause pipeline stalls. We demonstrate in our experiments on real large-scale document data sets that SIVF operates at higher speed and with lower memory consumption than existing algorithms. Our performance analysis reveals that SIVF works at high speed by suppressing performance degradation factors of the number of instructions, cache misses, and branch mispredictionsrather than less similarity calculations.
Osteochondromyxoma in a Pediatric Spondyloepiphyseal Dysplasia Patient
Authors: Peng Sophia , Behbahani Mandana , Sharma Shelly , Wadhwani Nitin R. , Rastatter Jeff C. , Alden Tord D. 
Published: July 2022

Abstract
Purpose: Osteochondromyxomas are rare congenital bone tumors that have only been described in the context of Carney complex syndrome (CNC). Data on osteochondromyxomas as a separate entity and in association with other disorders remain limited, making both diagnosis and treatment difficult.Methods: A case report of a 17-year-old female diagnosed with sellar osteochondromyxoma is presented in the setting of spondyloepiphyseal dysplasia (SED). We discuss radiographic and histopathological interpretations in addition to reviewing current literature on osteochondromyxomas.Results: Successful gross total resection of the tumor was achieved via an endonasal endoscopic transsphenoidal approach. Diagnosis was established radiographically and pathologically. Conclusion:﻿ Diagnosis and treatment of osteochondromyxoma are best achieved via tissue biopsy. Following confirmed osteochondromyxoma cases long-term for recurrence and outcomes will be essential in understanding its natural tumor history and in establishing standard treatments.
Association of allergic symptoms and allergens with diabetes mellitus: a cross-sectional study based on NHANES 2005–2006
Authors: Lu Gan , Deng Yu-Qin , Xi Yang , Chen Shi-Ming , Kong Yong-Gang , Xu Yu , Li Fen , Tao Ze-Zhang 
Published: July 2022

Abstract
Background
Epidemiological evidence for the association of allergies with diabetes mellitus (DM) is limited.
Objective
To Investigate the association of allergic symptoms and allergens with DM by analyzing National Health and Nutrition Examination Survey (NHANES) data.
Methods
Data from 1687 subjects were screened from the 2005–2006 NHANES (n = 10348) data, and logistic regression models were built and stratified analysis was performed to describe the association of allergic symptoms and allergens with DM and the constraints in which they were associated.
Results
After adjusting for confounding factors, the stratified analysis found that the risk of allergic symptoms in DM patients increased by 1.847-fold, 1.646-fold, 3.859-fold, 2.862-fold, and 1.476-fold among the middle-aged, males, people with total household size of 3 or 4, and high blood pressure (HBP) patients, but decreased by 0.024-fold and 0.285-fold in people living alone or with normal weight. In females or when the total number of people in the household was 4, the risk of allergen sensitization in DM patients increased by 2.028-fold and 4.674-fold. Compared with people without DM, people with DM had a 1.585-fold increased risk of developing a D. Pteronyssinus allergy and a 0.372-fold lower risk of developing an oak allergy.
Conclusions
DM is a risk factor for allergic symptoms and allergen sensitization under certain conditions and increases the risk of D. Pteronyssinus allergy and reduces the risk of oak allergy.
Repurposing of Spironolactone Towards Upregulation of the Expression of NKG2D Ligands in Metastatic Osteosarcoma Mouse Model
Authors: Khamarudin Farhana , Muhamad Mudiana , Ibahim Mohamad Johari , Zain Wan Nor I’zzah Wan Mohd , Ridzuan Nurul Raudzah Adib , Aziz Mardiana Abdul , Ab-Rahim Sharaniza 
Published: July 2022

Abstract
Osteosarcoma (OS) is the most common bone cancer affecting children with a high-grade malignancy characterised by severe lung metastases. Targeting tumour cell surface antigens have proven effective as alternative cancer treatments. Natural killer (NK) cells efficiently recognize and kill tumour cells through several mechanisms including the expression of ligands for NK cell-activating receptors. The NKG2D and its ligands are required for NK cells-mediated immune response to malignancies. Nonetheless, such therapeutic strategy remains elusive towards solid tumours, particularly metastatic OS. Here, we examine the efficiency of NK cells in tumour recognition by way of a repurpose drug, spironolactone (SPIR). The SPIR-treated cells (HOS-143B) were inoculated into male NOG mice to establish the metastatic OS model. The tumour was apparent in both group and lung metastasis was confirmed with H&E staining. Flow cytometry analysis showed a significant increase in the expression of the NKG2D ligands in tumour tissue induced by SPIR-treated OS-cells compared to control group. These findings revealed an alternative role of SPIR, as an immunosensitizing drug, indicated by the upregulation of NK cells ligands in the metastatic OS model. Hence, the repurposing of SPIR provides a promising approach towards a novel strategy of onco-immunotherapy for OS.
Parkinson’s disease causality and heterogeneity: a proteogenomic view
Authors: Messa Mirko , Kaiser Sergio , Zhang Luqing , Mollenhauer Brit , Jacob Jaison , Longerich Simonne , Del-Aguila Jorge , Marcus Jacob , Raghavan Neha , Stone David , Fagboyegun Olumide , Galasko Douglas , Dakna Mohammed , Bilican Bilada , Dovlatyan Mary , Kostikova Anna , Li Jingyao , Peterson Brant , Rotte Michael , Sanz Vinicius , Foroud Tatiana , Hutten Samantha , Frasier Mark , Iwaki Hirotaka , Singleton Andrew , Marek Ken , Crawford Karen , Elwood Fiona , Serrano-Fernandez Pablo 
Published: July 2022

Abstract
The pathogenesis and clinical heterogeneity of Parkinson’s disease have been evaluated from molecular, pathophysiological, and clinical perspectives. High-throughput proteomic analysis of CSF has opened new opportunities for scrutinizing this heterogeneity. To date, this is the most comprehensive CSF-based proteomics profiling study in Parkinson’s disease (1103 patients, 4135 proteins). Combining CSF aptamer-based proteomics with genetics we determined protein quantitative trait loci (pQTLs). Analyses of pQTLs together with summary statistics from the largest Parkinson’s disease genome wide association study (GWAS) identified 68 potential causal proteins by Mendelian randomization. The top causal protein, GPNMB was previously reported to be upregulated in the substantia nigra of Parkinson’s disease patients.
We also compared the CSF proteomes of patients and controls. The Parkinson’s disease cohort comprised not only LRRK2+ and GBA+ mutation carriers but also idiopathic patients. Proteome differences between GBA+ patients and unaffected GBA+ controls suggest degeneration of dopaminergic neurons, altered dopamine metabolism and increased brain inflammation. The proteins discriminating LRRK2+ patients from unaffected LRRK2+ controls, revealed dysregulated lysosomal degradation, as well as altered alpha-synuclein processing, and neurotransmission. Proteome differences between idiopathic patients and controls suggest increased neuroinflammation, mitochondrial dysfunction / oxidative stress, altered iron metabolism and potential neuroprotection mediated by vasoactive substances.
Finally, we used proteomic data to stratify idiopathic patients into "endotypes". The identified endotypes show differences in cognitive and motor disease progression based on the use of previously reported protein-based risk scores.
In summary, we: i) identified causal proteins for Parkinson’s disease, ii) assessed CSF proteome differences in Parkinson’s disease patients of genetic and idiopathic etiology, and. iii) stratified idiopathic patients into robust clinically relevant subtypes. Our findings not only contribute to the identification of new therapeutic targets but also to shaping personalized medicine in CNS neurodegeneration.
Taxonomic update of species closely related to Fulvifomes robiniae in America: F. popoffii sp. nov.
Authors: Salvador-Montoya Carlos A. , Martínez Mariana , Drechsler-Santos Elisandro Ricardo 
Published: July 2022

Abstract
Fulvifomes robiniae is a parasitic polypore with distribution in temperate zones of North America. However, specimens morphologically similar to F. robiniae are found in other parts of America. In addition, species such as F. cedrelae and F. coffeatoporus are related to F. robiniae in morphology. In this work, the material type of F. robiniae, F. cedrelae F. coffeatoporus, F. krugiodendri, F. centroamericanus, and F. swieteniae were revised. Furthermore, phylogenetic inferences of species studied were performed. Based on our results, F. swieteniae and F. centroamericanus are synonymized in F. cedrelae and F. krugiodendri in F. coffeatoporus. Also, F. cedrelae and F. coffeatoporus are confirmed as distinct species of F. robiniae based on molecular data. Additionally, specimens that resemble F. robiniae in northern Argentina were found. Based on morphological, molecular, and ecological data, these specimens are resolved as a distinct entity from F. robiniae. Here presented as new, F. popoffii sp. nov. Illustrations, taxonomic analyses, a discussion is presented, and a Fulvifomes species key from America is provided.
The impact of UAS aerial ignition on prescribed fire: a case study in multiple ecoregions of Texas and Louisiana
Authors: Lawrence Brett , Mundorff Kevin , Keith Eric 
Published: July 2022

Abstract
Background: Small Unmanned Aerial System (UAS) technologies and their applications have expanded in recent years, to include aerial ignition support in prescribed fire and wildland fire settings. In 2019, we incorporated the use of UAS aerial ignition into our existing prescribed fire program of over twenty years. To assess its impact, comparisons of UAS and non-UAS burns were performed on burn data from 2012 to 2021, with 59 total UAS burns conducted from 2019 to 2021. We hypothesized that the UAS was responsible for more burning day-1 on average, and that it did so without negatively impacting burn results.Results: Non-parametric significance tests were used to analyze the relationship between using the UAS and ha day-1 burned, and the results of post-burn assessment where the UAS was and was not used. Principal findings were that UAS aerial ignition increased average ha day-1 burned by 65 or 125%, and post-burn assessment results were unaffected when using the UAS. The correlation of days burned, and hectares burned was also reduced after introduction of the UAS.Conclusions: A large increase in ha day-1 was previously unachievable, making the UAS a viable tool for accomplishing safer and more effective prescribed burn operations in the limited number of suitable days available. When managed responsibly, UAS aerial ignition is poised to have a positive impact on the safe and effective application of prescribed fire, resulting in more achievable conservation and fuel management goals.
Novel bacterial consortium SPB92 for the bioremediation of textile dye Acid Orange
Authors: BERA SWETA PARIMITA , Godhaniya Manoj , Patel Khushboo 
Published: July 2022

Abstract
Textile effluent generated during the dyeing process of textiles is a huge supplier to water toxicity all over the world. Textile dyes are the main toxic component found in the effluent sample which is difficult to treat. A bacterial consortium capable of decolourizing and degrading the textile dye acid orange is reported in this research article. The bacterial consortium was identified by 16S rDNA sequence and phenotypic characteristics. It is composed of four strains i.e., Pseudomonas stutzeri (MW219251), Bacillus tequilensis (MW110471), Bacillus flexus (MW131645), Kocuria rosea (MW132411). The consortium was able to cause decolorization of azo dye acid orange (30 mg/L) in 23 h, when kept under static laboratory conditions. The optimal pH and temperature for color removal were pH 7.5 and 32° C, respectively. The decolorization of dye before and after was checked by UV-Visible absorption spectra. This gives evidence that decolorization was caused due to biodegradation. This was further assured by studying the reduction of biological oxygen demand (BOD5) (96%), chemical oxygen demand (COD) (79%), total dissolved solids (TDS) (80%), total suspended solids (TSS) (65%), and total organic carbon (TOC) (54%) of the bacterial-treated water sample. The strain showed significant activities of azoreductase (85%), laccase (87%), and NADH-DCIP reductase (69%) at 21 h, 16 h, and 11 h of growth respectively indicating evidence for reductive cleavage of the dye. The Fourier transform-infrared spectroscopy (FT-IR) spectroscopy and gas chromatography-mass spectroscopy (GC-MS) results confirmed the mineralization of the dye. The results indicate the effectiveness of the bacterial consortium SPB92 in the biodegradation of acid orange dye. This demonstrates that the consortium has immense potential and will serve as an important contributor to the treatment of textile wastewater.
Reducing the production of Acrylamide During the Roasting of Balloon Flower Roots in Consumer Appliances and Industrial Equipment
Authors: Lee Min Gyu , Han Hyebin , Lee Suyoon , Ham Seung Hwan , Choi Young Jin , Hahn Jungwoo 
Published: July 2022

Abstract
This study aimed to determine what conditions were needed to reduce the production of acrylamide when balloon flower roots (Platycodon grandiflorum (Jacq. A. DC.)) were heated. The conditions of temperature and length of time and the type of equipment needed for heating (i.e., consumer appliance or industrial equipment) were the important variables in the experiment. The official criterion for safe levels of acrylamide is less than 1,000 µg/kg as determined by the Ministry of Food and Drug Safety in South Korea. Raw samples were roasted in consumer appliances and industrial equipment in nine conditions. A response surface methodology was used to determine whether the heated samples met the safety requirements. The most significant condition for consumer appliances was time and for industrial equipment was temperature. The optimal roasting time was 3.01 min with a consumer appliance and 4.18 min with industrial equipment at 110℃, a typical temperature in the field. The acrylamide content of the tested sample was significantly in agreement with the predicted amount (R2 > 0.950).