bluuebunny/crossref_metadata_2025_split huggingface dataset:
Application of Half‐Sandwich Metal‐Phosphinite Compounds to Biological Activities: Determine the energies of the HOMO and LUMO levels
Authors: Meriç Nermin , Rafikova Khadichakhan , Zazybin Alexey , Güzel Remziye , Kayan Cezmi , Elma Karakaş Duygu , Dündar Abdurrahman , ISLAM Sholpan , Okumuş Veysi , Aydemir Murat 
Published: October 2022

AbstractMononuclear transition metal complexes 1‐(furan‐2‐yl)ethyldiphenyl[dichloro(η6‐p‐cymene)ruthenium(II)]phosphinite, (2), 1‐(furan‐2‐yl)ethyldiphenyl[dichloro(η6‐benzene) ruthenium(II)] phosphinite (3), 1‐(furan‐2‐yl)ethyldipheny[chloro(η4‐1,5‐cyclooctadiene)rhodium(I)]phosphinite (4), 1‐(furan‐2‐yl)ethyldiphenyl[dichloro (η5pentamethylcyclopentadienyl)iridium (III)] phosphinite (5) were synthesized and characterized by microanalysis, infrared, MS, and NMR spectroscopy. The biological activities of the complexes were also tested. Compounds 2 and 5 were the best complexes at DPPH radical scavenging and reducing power activity at 73.27 % and 0.41 at 200 μg/mL, respectively. The highest antimicrobial activity exhibited by complex 3 as 14 mm inhibition zone against S. aureus. All of the complexes have cleaved the DNA from the double‐strand and exhibited three bands on gel electrophoresis. Moreover, cyclic voltammetry studies of the phosphinite complexes were carried out to determine the energies of the HOMO and LUMO levels as well as to estimate their electrochemical and some electronic properties.
Simulation: A Historical and Pedagogical Perspective
Authors: Karlsaune Hanne , Antonsen Therese , Haugan Gørill 
Published: October 2022

Abstract
I hear and I forget.
I see and I remember.
I do and I understand.
—Confucius 551–479 BCE
Simulation is increasingly used in nursing education to supplement clinical and didactic learning activities. Simulation is a technique for practice and learning that can be used in many different disciplines as well as for trainees. Simulation is a technique (not a technology) aiming at replacing real experiences with guided ones; that is, it represents a context in which students can exercise and explore various aspects of a specific practical skill. Accordingly, simulation-based learning signifies a useful approach to develop health professionals’ knowledge, skills, and attitudes while protecting patients from unnecessary risks. Simulation involves learning situations that take place under the supervision of an expert or lecturer and is commonly applied as an active learning method in different health disciplines like nursing, social education, radiography, and medicine. This chapter concentrates on historical and pedagogical perspectives of simulation as a learning method in nursing education. Simulation as a learning method builds on pedagogical adult learning theory, with an emphasis on David A. Kolb and Donald Schön’s concepts experience-based learning, reflection-on-action, and reflection-in-action. Simulation-based learning is appropriate for topics such as patient safety, teamwork, and quality of health services. The literature states that simulation contributes positively to nursing students’ situational awareness, their ability to formulate and predict possible consequences of action implemented, decision-making, communication, and teamwork.
How to Use Simulation as a Learning Method in Bachelor and Postgraduate/Master Education of Nurses and Teachers in Healthcare
Authors: Akselbo Iben , Aune Ingvild 
Published: October 2022

AbstractIn this chapter, results from three different studies about simulation as a learning method are presented and discussed alongside relevant pedagogical theory and other research. These studies were conducted at a university in Norway from 2018 to 2020. The studies used a qualitative approach, and reflection notes and focus group interviews were used to collect data. The participants (81 students in total) were bachelor of nursing students 2nd year public health nursing students, and students in teacher training (healthcare). The interviews were conducted shortly after the students had performed the simulation activity. The students expressed that the simulation provided a higher degree of realism and seriousness than skill training did. They felt that the simulation was an educational method in which they experienced realistic feelings and stress in a serious situation. The students learned that in an emergency, good communication is important to make the right decision. The simulation was perceived as one of the most effective ways to prepare themselves for the profession of nursing. They experienced learning through describing the course of events during the debriefing process and obtaining feedback from other students to reveal the gaps in their knowledge.
Training Interprofessional Teamwork in Palliative Care: A Pilot Study of Online Simulation Activity for Registered Nurses and Nursing Associates
Authors: Rønsen Astrid , Tosterud Randi 
Published: October 2022

AbstractPalliative care promotes quality of life for seriously ill and dying patients and their loved ones. An ageing population with more complex chronic and life-limiting conditions will increase the demand for competence in the field. Interprofessional cooperation will be a critical factor in achieving this. Such cooperation within the field of nursing is critical because of registered nurses’ (RNs) role and function in patient- and family-centred care. A project focusing on learning interdisciplinary teamwork using simulation as a learning approach was established. Two groups of students participated in the project: one group consisted of 17 nursing associates who were participating in a 2-year part-time study programme in cancer care and palliative care at a vocational college. The second group was made up of 28 RNs, a social worker and learning disability nurses, all postgraduate students taking part in a part-time interdisciplinary programme in palliative care at master’s degree level.Simulation activity is usually conducted with participants physically present, but because of the COVID-19 pandemic situation, this was not possible. A pilot project was conducted where simulation activity was tried out as online learning. RNs and nursing associates (NA) participated, and their cooperation was focused on palliative/end-of-life care. They were all trained clinicians in two different study programmes.In this chapter, we present how simulation activity with participants physically present was transformed into an online learning situation. A brief presentation of students’ and teachers’ reflections on the pedagogical advantages and disadvantages of such a transition is also included.
The Use of Critical Response Process as a Debriefing Structure in Simulation Activity in Nursing Education
Authors: Haugom Jon Viktor , Tosterud Randi 
Published: October 2022

AbstractIn the use of simulation activity as a learning approach, the debriefing phase is considered as crucial to achieve learning. In debriefing, the participants reflect and discuss what happened in the scenario. Feedback is an important factor, and research shows that there must be certain conditions present to achieve learning from feedback. The facilitator and the structure used impact on these conditions. In this chapter, we will present a new structure for debriefing in simulation based on a study focusing on how the structure affects the facilitator role.
Learning Without a Teacher: Perceptions of Peer-to-Peer Learning Activities in Simulation Training
Authors: Degn Lise , Selberg Hanne , Markussen Anne-Lene Rye 
Published: October 2022

AbstractThis chapter reports from an experimental study carried out at University College Copenhagen. In the experiment, fifth-semester nursing students were subjected to an intensified simulation intervention, combined with supporting elements designed to increase collaborative and peer learning. One supporting element was a series of peer-to-peer sessions in which students in small groups trained technical nursing skills for mastery learning, e.g., duodenal tube placement. We describe the study and analyze how the students perceive strengths and weaknesses of the peer-to-peer format and how these perceptions seem to be linked to the students’ perceptions of learning and authority. We discuss how the method may be a positive addition to simulation training in nursing education and particularly how the role of the teacher should be conceived.
Klee’s Measure Problem Made Oblivious
Authors: Thießen Thore , Vahrenhold Jan 
Published: October 2022

AbstractWe study Klee’s measure problem — computing the volume of the union of n axis-parallel hyperrectangles in $$\mathbb {R}^d$$

R

d

— in the oblivious RAM (ORAM) setting. For this, we modify Chan’s algorithm [12] to guarantee memory access patterns and control flow independent of the input; this makes the resulting algorithm applicable to privacy-preserving computation over outsourced data and (secure) multi-party computation.For $$d = 2$$

d
=
2

, we develop an oblivious version of Chan’s algorithm that runs in expected $$\mathcal {O}(n \log ^{5/3} n)$$

O
(
n

log

5
/
3

n
)

time for perfect security or $$\mathcal {O}(n \log ^{3/2} n)$$

O
(
n

log

3
/
2

n
)

time for computational security, thus improving over optimal general transformations. For $$d \ge 3$$

d
≥
3

, we obtain an oblivious version with perfect security while maintaining the $$\mathcal {O}(n^{d/2})$$

O
(

n

d
/
2

)

runtime, i. e., without any overhead.Generalizing our approach, we derive a technique to transform divide-and-conquer algorithms that rely on linear-scan processing into oblivious counterparts. As such, our results are of independent interest for geometric divide-and-conquer algorithms that maintain an order over the input. We apply our technique to two such algorithms and obtain efficient oblivious counterparts of algorithms for inversion counting and computing a closest pair in two dimensions.
An alternative equation for generalized monomials
Authors: Boros Zoltán , Menzer Rayene 
Published: October 2022

AbstractIn this paper we consider a generalized monomial or polynomial $$ f : \mathbb {R}\rightarrow \mathbb {R}$$

f
:
R
→
R

that satisfies the additional equation $$ f(x) f(y) = 0 $$

f
(
x
)
f
(
y
)
=
0

for the pairs $$ (x,y) \in D \,$$

(
x
,
y
)
∈
D

, where $$ D \subseteq {\mathbb {R}}^{2} $$

D
⊆

R

2

is given by some algebraic condition. In the particular cases when f is a generalized polynomial and there exist non-constant regular polynomials p and q that fulfill $$\begin{aligned} D = \{\, (p(t),q(t)) \,\vert \, t \in \mathbb {R}\,\} \end{aligned}$$

D
=
{

(
p
(
t
)
,
q
(
t
)
)

|

t
∈
R

}

or f is a generalized monomial and there exists a positive rational m fulfilling $$\begin{aligned} D = \{\, (x,y) \in {\mathbb {R}}^{2} \,\vert \, x^2 - m y^2 = 1 \,\}, \end{aligned}$$

D
=
{

(
x
,
y
)

∈

R

2

|

x
2

-
m

y
2

=
1

}
,

we prove that $$ f(x) = 0 $$

f
(
x
)
=
0

for all $$ x \in \mathbb {R}\,$$

x
∈
R

.
Automated quality control inspection of geometric tip defects in medical needle manufacturing
Authors: Wang Xiaoying , Jowers Casey , Mazur Maciej , Buddery Alexander , Kent Damon , Bab-Hadiashar Alireza , Easton Mark 
Published: October 2022

AbstractThe manufacture of In Vitro Fertilization (IVF) needles is subject to the most stringent quality demands. This makes automated inspection challenging due to difficulty in reliably classifying conforming and non-conforming (defective) products due to factors including multidimensional variation of their tip geometry and the lack of an explicit quality standard. In addition, developing an IVF needle image dataset, which broadly contains the visual characteristics of qualified and defective products, is difficult without commissioning large and costly production runs. The most important original contribution of this work is a new solution to investigate and quantify the uncertainty in the quality standard of IVF needles by integrating inter-disciplinary techniques. This work utilizes a low-cost, virtual dataset of synthetic images, generated by the automated photo-realistic rendering of a three-dimensional (3D) parametric model to simulate manufacturing variation. Then, the unknown numerical (critical) quality thresholds are obtained by estimating the relationship between quality response and measurement predictors using an Ordinal Logistic Regression (OLR) algorithm on the synthetic images. The fitted models exhibited increased overall predictive accuracy of up to 11.02% than the machine learning models (available in MATLAB) and could provide objective guidance on classifying specific quality aspects of a product.
Comparison of [99mTc]Tc-tilmanocept with [99mTc]Tc-sulphur colloids and [99mTc]Tc-albumin colloids for sentinel lymph node detection in patients with cutaneous malignancies of the head
Authors: Ooms Mark , von Mallek Dirk , Kaiser Hans-Jürgen , Hölzle Frank , Mottaghy Felix M. , Modabber Ali 
Published: October 2022

Abstract
Purpose
Sentinel lymph node (SLN) biopsy is a staging procedure in the management of cutaneous malignancies of the head. The ideal radiopharmaceutical is controversial. This study aimed to compare [99mTc]Tc-tilmanocept (TcTM) with [99mTc]Tc-sulphur colloid (TcSC) and [99mTc]Tc-albumin colloid (TcAC) for SLN detection in the head and neck region.

Methods
Data from 62 patients with cutaneous malignancies of the head who were injected with TcTM, TcSC, or TcAC before SLN imaging (SLN-I) and SLN excision (SLN-E) between 2012 and 2021 were retrospectively analysed. SLN-I was performed using planar lymphoscintigraphy and SPECT/CT, and a gamma probe was used for SLN-E. The SLN-I localisation rate (patients with SLNs) and degree (SLN number) and SLN-E relocalisation rate (patients with SLNs) and ratio (SLN number in SLN-E/SLN number in SLN-I) were compared between TcTM, TcSC, and TcAC.

Results
TcTM showed similar SLN-I localisation rates for primaries in the anterior and posterior head region compared with TcSC (84.6% vs. 72.4%, p=0.680; both 100.0%) and TcAC (84.6% vs. 75.0%, p=1.000; both 100.0%). The SLN-I localisation degree for TcTM was higher for primaries in the anterior head region and similar for primaries in the posterior head region compared with TcSC (3.2 vs. 2.3, p=0.034; and 1.8 vs. 2.2, p=0.506) and TcAC (3.2 vs. 2.0, p=0.038; and 1.8 vs. 2.7, p=0.329). The SLN-E relocalisation rates and ratios were similar for all.

Conclusion
On the basis of a limited study design that compared three different tracers in three different patient groups, TcTM showed comparable overall performance to TcSC and TcAC.
Preparation and evaluation of the antimicrobial activity of sodium alginate-grafted diphenylamine embedded with silver nanoparticles
Authors: Mohamed Fatma , Ahmed Asmaa , Abdel-Gawad Omayma F. 
Published: October 2022

AbstractAntibiotic nanocomposite polymers show great promise in treating a variety of pathogens that cause widespread disease. Sodium alginate-grafted diphenylamine (NaAlg-g-DPA) embedded with different ratios of silver nanoparticles (AgNPs) was fabricated and characterized through different techniques including FTIR, XRD, and SEM techniques for investigating the antimicrobial activity. XRD confirmed the crystallinity of these compounds, and the average crystal size of Na Alg-g-DPA/Ag was estimated to be 48.6 nm. Then it was applied as an antimicrobial agent and evaluated through two ways (inhibition zone and MIC techniques) against Staphylococcus aureus as gram-positive bacteria with an inhibition zone of 19.31.6 mm and 18.60.63 mm against Escherichia coli as gram-negative bacteria while with increasing the Ag ratio 2:1 there was an enhancement in their biological activity to be 21.90.69 mm against Staphylococcus aureus and with an inhibition zone of 21.32.1 mm against Escherichia coli. The outcomes of this investigation are important for the development of new composite materials with antibacterial properties for industrial applications.
Long-Term Effectiveness of an Online Self-help Intervention for People with HIV and Depressive Symptoms
Authors: van Luenen Sanne , Garnefski Nadia , Spinhoven Philip , Kraaij Vivian 
Published: October 2022

AbstractThe aim of this study was to investigate the long-term effectiveness (3–4 years later) of an online intervention that was previously found to effectively reduce depressive symptoms in people with HIV on the short term. Participants were people with HIV who had participated in the large RCT on the short-term effectiveness of the guided online intervention. The primary outcome measure was depressive symptoms [Patient Health Questionnaire-9 (PHQ-9)] and the secondary outcome measure was anxiety symptoms [Generalized Anxiety Disorder-2 (GAD-2) scale]. Forty-seven participants completed the long-term follow-up. PHQ-9 scores, previously found to have been significantly reduced on the short term, remained low on the long term. GAD-2 scores did not decrease significantly on the short term, however, on the long term, a significant decrease was found. The intervention may not only be effective in lowering depressive symptoms on the short term but also retain the results on the long term.Trial registration International Clinical Trials Registry Platform, NL8448, March 3, 2020.
Gröbner Bases for Fusion Products
Authors: Flake Johannes , Fourier Ghislain , Levandovskyy Viktor 
Published: October 2022

AbstractWe provide a new approach towards the analysis of the fusion products defined by B. Feigin and S. Loktev in the representation theory of (truncated) current Lie algebras. We understand the fusion product as a degeneration using Gröbner theory of non-commutative algebras and outline a strategy on how to prove a conjecture about the defining relations for the fusion product of two evaluation modules. We conclude with following this strategy for $\mathfrak {sl}_2(\mathbb {C}[t]) $

s
l

2

(
ℂ
[
t
]
)
and hence provide yet another proof for the conjecture in this case.
Decreased left atrial function in obesity patients without known cardiovascular disease
Authors: Aga Y. S. , Kroon D. , Snelder S. M. , Biter L. U. , de Groot-de Laat L. E. , Zijlstra F. , Brugts J. J. , van Dalen Bas M. 
Published: October 2022

AbstractObesity is a risk factor for heart failure with preserved ejection fraction (HFpEF). We hypothesized that assessment of left atrial (LA) strain may be useful to reveal precursors of HFpEF in obesity patients. Echocardiograms of obesity patients without known cardiovascular disease who underwent bariatric surgery, and echocardiograms of age- and gender matched controls were analyzed. The echocardiogram was repeated 1 year after bariatric surgery. LA reservoir strain (LASr), LA conduit strain (LAScd), and LA contractile strain (LASct) were measured. 77 Obesity patients were compared with 46 non-obese controls. Obesity patients showed a significantly decreased LA function compared with non-obese individuals (LASr 32.2% ± 8.8% vs. 39.6% ± 10.8%, p < 0.001; LAScd 20.1% ± 7.5% vs. 24.9% ± 8.3%, p = 0.001; LASct 12.1% ± 3.6% vs. 14.5% ± 5.5%, p = 0.005). There was no difference in prevalence of diastolic dysfunction between the obesity group and controls (9.1% vs. 2.2%, p = 0.139). One year after bariatric surgery, LASr improved (32.1% ± 8.9% vs. 34.2% ± 8.7%, p = 0.048). In the multivariable linear regression analysis, BMI was associated with LASr, LAScd, and LASct (β =  − 0.34, CI − 0.54 to − 0.13; β =  − 0.22, CI − 0.38 to − 0.06; β =  − 0.10, CI − 0.20 to − 0.004). Obesity patients without known cardiovascular disease have impairment in all phases of LA function. LA dysfunction in obesity may be an early sign of cardiac disease and may be a predictor for developing HFpEF. LASr improved 1 year after bariatric surgery, indicating potential reversibility of LA function in obesity.
Adverse health and environmental outcomes of sewage treatment plant on surrounding groundwater with emphasis on some mitigation recommendations
Authors: Kandil A. T. , Haggag K. , Gamal A. A. , Abd El-Nasser M. G. , Mostafa W. M. 
Published: October 2022

AbstractWater quality deterioration hinders economic and social development in developing countries that are facing freshwater security and shortages. Based on the collection of 29 water samples, this study focused on the relationship between sewage treatment plant and groundwater system surrounding it using multidisciplinary approach that combines the characterization of groundwater system and its connection with surrounding canal and drains, using chemical and isotopic characterization revealing that there is a direct relation between the surface water system and surrounding groundwater system. About 58% of the groundwater samples and all surface water samples in the investigated area are threatened by high concentrations of trace elements. The multivariate statistical analysis elucidates that anthropogenic effect and fertilizers sewage contamination are the main causes of groundwater pollution. Nearly, 31% and 11.5% of groundwater samples were posing oral chronic non-carcinogenic health risk and dermal chronic risk for adult, respectively, while all surface water samples were posing oral chronic non-carcinogenic health risk, with no dermal hazard. The uncharged species of Fe and Al are expected to be more mobile in groundwater because they would not be attracted to the surface charge of minerals. Inorganic ligands (HCO3−, SO42−, Cl−, and NO3−) act as nucleation centers that were linked with those trace elements creating new species with higher solubility degree in water that are transported away randomly for long distances in the water path.
Environmental assessment of road freight transport services beyond the tank-to-wheels analysis based on LCA
Authors: Osorio-Tejada Jose Luis , Llera-Sastresa Eva , Scarpellini Sabina 
Published: October 2022

AbstractReducing environmental impacts in transport motivates many studies to offer more sustainable freight services. However, most methodologies focus on impacts from fuel consumption, and approaches trying to integrate other transport components have not facilitated its application to actual and specific transport services. In this study, we present a harmonized approach to address the transport services with a holistic way to increase the knowledge about hotspots of the transport sector based on the life cycle assessment methodology. In this framework, vehicle manufacturing, fuel production, and infrastructure construction are the key transport components around the traffic process. Besides fuel usage, the operation and maintenance of vehicles and infrastructures are also included. We developed a tool to create the life cycle inventories for each transport component to be applied to specific transport services in any location with a comprehensive view and low uncertainty in the results. This approach was applied to road-freight services in Colombia, Malaysia, and Spain. The main results showed the nature and origin of the environmental impacts, which are highly influenced by the emissions control technologies, road characteristics, and traffic volume. The contribution of atmospheric pollutants per tonne-km can decrease by a quarter when Euro VI trucks on highways instead of conventional trucks on single-lane roads are used. However, these contributions are highly affected by fuel production due to the origin of biofuels. The proposed methodology provides relevant information to estimate transport impacts in the life cycle assessment of products with superior precision and identify strategies for systemically improving sustainability.
Remarks on double points of plane curves
Authors: Gimigliano Alessandro , Idà Monica 
Published: October 2022

AbstractWe study the relation between the type of a double point of a plane curve and the curvilinear 0-dimensional subschemes of the curve at the point. An Algorithm related to a classical procedure for the study of double points via osculating curves is described and proved. Eventually we look for a way to create examples of rational plane curves with given singularities $$A_s$$

A
s

.