bluuebunny/crossref_metadata_2025_split huggingface dataset:
A framework for IoT and blockchain based smart food chain management system
Authors: Singh Akhilesh Kumar , Raza Zahid 
Published: November 2022

SummaryThe worldwide food supply chain network firms have embraced digitalization and have changed customers' everyday lives in serval viewpoints. This work proposes a framework for IoT and Blockchain based smart Food Chain Management System (IBFS) aiming to regulate the food inventory systems in an organization focusing on the safety and nature of the items conveyed to the end consumers. The proposed IBFS framework is an IoT‐based blockchain with smart contract architecture for trust, reliability, and transparency. A Message Queue Telemetry Transport (MQTT) (Message Queue Telemetry Transport) broker or server is deployed on the broadcast to record all data collected from the IoT sensors. The data provided by IoT‐sensors or devices is pooled and gathered by MQTT based cloud brokers and the shipment's geolocation, movement, and temperature are logged. The work uses two types of smart contracts based on Ethereum‐based blockchain technology (BCT) environment as the operational backbone written in the Solidity language. The first smart contract deals with custody and the second smart contract deals with shipment or transportation to track the produce. The food supply chain process evaluates the collected data from the IoT sensors managed with the help of blockchain and MQTT servers. The quality of food is measured by evaluating by temperature and humidity function, transition time, final item and for validation of smart contracts. Performance evaluation of IBFS in terms of Gas cost under various test conditions prove the effectiveness of the work.
Enhanced Host‐Guest Association and Fluorescence in Copolymers from Copper Salphen Complexes by Supramolecular Internalization of Anions
Authors: Hernández‐Pacheco Paulina , Zelada‐Guillén Gustavo A. , Romero‐Ávila Margarita , Cañas‐Alonso Roberto Carlos , Flores‐Álamo Marcos , Escárcega‐Bobadilla Martha V. 
Published: November 2022

AbstractInvited for this month's cover are Prof. Escárcega‐Bobadilla and Prof. Zelada‐Guillén, collaborators from the National Autonomous University of Mexico (UNAM). The cover picture shows the X‐ray structure of a chartreuse fluorescent Salphen‐Cu complex that upon copolymerization receives dielectric protection from the rest of the chain in solution. This enables cyan luminescence at higher intensity via anion‐guest engulfment which renders dimmer‐like turn‐on emission. More information can be found in the Research Article by G. Zelada‐Guillén, M. V. Escárcega‐Bobadilla, and co‐workers.
Influence of the Rancimat Apparatus Operating Parameters on Oxidative Stability Determination of Cold‐Pressed Camelina and Hemp Seed Oil
Authors: Symoniuk Edyta , Łapińska Aneta , Ratusz Katarzyna , Wroniak Małgorzata 
Published: November 2022

AbstractThe study investigates the impact of operating parameters such as temperature (90, 100, 110, 120 °C), airflow rate (10, 15, 20 L h−1), and sample weight (3, 6, 9 g) on the oxidative stability of cold‐pressed camelina and hemp seed oils using the Rancimat apparatus. Conducted analysis indicates a significant influence of temperature on oils' induction time. Moreover, higher airflows should be selected at high analysis temperatures. Based on the calculated parameters of the oxidation kinetics, it was shown that hemp oil has higher activation energy values than camelina oil. Response surface methodology (RSM) indicates that to minimize the determination time of camelina oil oxidation, the following analysis conditions should be selected: sample weight (SW) = 33.5 g, airflow (AF) = 20 L h−1, and temperature (T) = 120 °C. However, for hemp oil, these parameters should be SW = 5.56 g, AF = 15 L h−1, T = 120 °C. Sample mass does not significantly impact oils induction time, which depends mainly on the temperature and airflow.Practical applications: The conducted research shows that the parameters of the cold‐pressed camelina and hemp oils oxidative stability have to be determined experimentally. The determined parameters for assessing the oxidative stability will reduce the analysis time and the possibility of interpolating the obtained result at different temperatures and analysis parameters.
Outcomes of patients with Wilms' tumour stage III due to positive resection margins only: An analysis of patients treated on the SIOP‐WT‐2001 protocol in the UK‐CCLG and GPOH studies
Authors: Vujanić Gordan M. , Graf Norbert , D'Hooghe Ellen , Chowdhury Tanzina , Vokuhl Christian , Al‐Saadi Reem , Pritchard‐Jones Kathy , Melchior Patrick , Furtwängler Rhoikos 
Published: November 2022

AbstractStage III Wilms' tumour (WT) represents a heterogeneous group which includes different criteria, but all stage III patients are treated according to the same study regiment. The aim of the study was to retrospectively analyse outcomes in patients with stage III due to positive resection margins (RM) only, sub‐grouped in RM with viable (RM‐v) and nonviable (RM‐nv) tumour. Patients were treated pre‐ and postoperatively according to the SIOP‐WT‐2001 protocol in the UK‐CCLG and GPOH WT trials and studies (2001‐2020). There were 197 patients, including 134 with localised, abdominal stage III and 63 with overall stage IV, but abdominal stage III. Stage III due to RM‐v had 126 patients, and due to RM‐nv 71 patients. The overall 5‐year local‐relapse‐free survival (RFS), event‐free (EFS) and overall survival (OS) estimates for all patients with abdominal stage III RM were 95.7% (±SE1.5%), 85.1 (±SE2.6%) and 90.3% (±SE2.2%), respectively. Patients with stage III RM‐nv had significantly better RFS and EFS than patients with RM‐v (P = .027 and P = .003, respectively). A multivariate analysis showed that RM‐v remained a significant factor for EFS when adjusted for age, presence of metastasis at diagnosis, histological risk group and overall stage in Cox regression analysis (P = .006). Patients with stage III due to RM‐nv only exhibited no local recurrence and have a significantly better RFS and EFS than patients with RM‐v. The results suggest that exclusion of RM‐nv as a stage III criterion in the UMBRELLA staging system and consequent treatment reduction is warranted.
Methimazole‐induced gestational hypothyroidism affects the offspring development and differently impairs the conditioned fear in male and female adulthood rodents
Authors: Hipólito Laísa T. M. , Batista Tatiane H. , dos Anjos‐Garcia Tayllon , Giusti‐Paiva Alexandre , Vilela Fabiana C. 
Published: November 2022

AbstractGestational hypothyroidism is a prevalent disorder in pregnant women and also impairs fetal development with relevant outcomes. One of the outcomes of greatest interest has been rodent fear‐ and anxiety‐like behavior. However, the relationship between maternal hypothyroidism and onset of conditioned fear‐related responses in offspring remains controversial. Here, we used a well‐validated methimazole‐induced gestational hypothyroidism to investigate the behavioral consequences in offspring. Dams were treated with methimazole at 0.02% in drinking water up to gestational Day 9. Maternal body weights and maternal behavior were evaluated, and the puppies ware analyzed for weight gain and physical/behavioral development and assigned for the open field and fear conditioning test. Methimazole‐induced gestational hypothyroidism induced loss in maternal and litter weight, increases in maternal behavior, and impairs in offspring developmental landmarks in both male and female rodents. Only male offspring enhanced responsiveness to conditioned fear‐like behavior in adulthood.
North American genetic counselors' approach to collecting and using ancestry in clinical practice
Authors: Hubbel Alexandra , Hogan Elizabeth , Matthews Anne , Goldenberg Aaron 
Published: November 2022

AbstractCurrent guidelines from the National Society of Genetic Counselors (NSGC) recommend that patients' ancestry be obtained when taking a family history. However, no study has explored how consistently genetic counselors obtain or utilize this information. The goals of this study included assessing how genetic counselors collect their patients' ancestry, what factors influence this decision, and how they view the utility of this information. Genetic counselors working in a direct patient care setting in the US or Canada were recruited to participate in an anonymous survey via an NSGC email blast. Most participants (n = 115) obtain information about their patients' ancestry (96.5%), with the most common methods being directly asking the patient (91%) and utilizing intake forms (43.2%). Of participants who ask about ancestry directly, 50.5% always ask about the presence of Ashkenazi Jewish ancestry and 70.3% always ask about additional ancestries, suggesting that for most genetic counselors’ collection of ancestry is standard practice. However, the clinical utility of ancestry information is highly variable, with the impact on genetic testing choice being particularly low. A slight majority of participants support a reevaluation of current ancestry guidelines (51.3%), with many participants suggesting that the varying utility of ancestry in different clinical indications/specialties should be incorporated into guidelines. Despite being standard practice for most genetic counselors, no unified approach or standard for how ancestral information should be used in genetic counseling practice was identified.
Evaluation of extreme precipitation over Southeast Asia in the Coupled Model Intercomparison Project Phase 5 regional climate model results andHighResMIPglobal climate models
Authors: Hariadi Mugni Hadi , van der Schrier Gerard , Steeneveld Gert‐Jan , Ratri Dian Nur , Sopaheluwakan Ardhasena , Tank Albert Klein , Aldrian Edvin , Gunawan Dodo , Moine Marie‐Pierre , Bellucci Alessio , Senan Retish , Tourigny Etienne , Putrasahan Dian Ariyani , Linarka Utoyo Ajie 
Published: November 2022

AbstractModelling rainfall extremes and dry periods over the Southeast Asia (SEA) region is challenging due to the characteristics of the region, which consists of the Maritime Continent and a mountainous region; it also experiences monsoonal conditions, as it is located between the Asian summer monsoon and the Australian summer monsoon. Representing rainfall extremes is important for flood and drought assessments in the region. This paper evaluates extreme rainfall climatic indices from regional climate models from CORDEX Southeast Asia and compares them with the results of high‐resolution global climate models with a comparable spatial resolution from the HighResMIP experiment. Observations indicate a high intensity of rainfall over areas affected by tropical cyclones and long consecutive dry day periods over some areas in Indochina and the southern end of Indonesia. In the model simulations, we find that both coupled and sea surface temperature‐forced HighResMIP model experiments are more similar to the observations than CORDEX model results. However, the models produce a poorer simulation of precipitation intensity‐related indices due to model biases in the rainfall intensity. This bias is higher in CORDEX than in HighResMIP and is evident in both the low‐ and high‐resolution HighResMIP model versions. The comparable performances of HighResSST (atmosphere‐only runs) and Hist‐1950 (coupled ocean–atmosphere runs) demonstrate the accuracy of the ocean model. Comparable performances were also found for the two different resolutions of HighResMIP, suggesting that there is no improvement in the performance of the high‐resolution HighResMIP model compared to the low‐resolution HighResMIP model.
How did European firms adjust their corporate social responsibility investments during the global financial crisis?
Authors: Karmani Majdi , Uyar Ali , Kuzey Cemil 
Published: November 2022

AbstractThe crisis period of 2008 triggered European firms to undertake more corporate social responsibility (CSR) activities than during non‐crisis periods in all four dimensions, governance, economic, environmental, and social. The exogenous shock of 2008 significantly reduced European companies' profitability. The crisis period triggered firms to undertake more CSR activities than non‐crisis periods in all four dimensions, governance, economic, environmental, and social. Compared to other dimensions, corporate governance received more attention, implying that firms tried to alleviate the shock's disadvantages by strengthening their governance structures.
Artificial Intelligence‐Assisted Ultrasound Diagnosis on Infant Developmental Dysplasia of the Hip Under Constrained Computational Resources
Authors: Huang Bingxuan , Xia Bei , Qian Jikuan , Zhou Xinrui , Zhou Xu , Liu Shengfeng , Chang Ao , Yan Zhongnuo , Tang Zijian , Xu Na , Tao Hongwei , He Xuezhi , Yu Wei , Zhang Renfu , Huang Ruobing , Ni Dong , Yang Xin 
Published: November 2022

ObjectivesUltrasound (US) is important for diagnosing infant developmental dysplasia of the hip (DDH). However, the accuracy of the diagnosis depends heavily on expertise. We aimed to develop a novel automatic system (DDHnet) for accurate, fast, and robust diagnosis of DDH.MethodsAn automatic system, DDHnet, was proposed to diagnose DDH by analyzing static ultrasound images. A five‐fold cross‐validation experiment was conducted using a dataset containing 881 patients to verify the performance of DDHnet. In addition, a blind test was conducted on 209 patients (158 normal and 51 abnormal cases). The feasibility and performance of DDHnet were investigated by embedding it into ultrasound machines at low computational cost.ResultsDDHnet obtained reliable measurements and accurate diagnosis predictions. It reported an intra‐class correlation coefficient (ICC) on α angle of 0.96 (95% CI: 0.93–0.97), β angle of 0.97 (95% CI: 0.95–0.98), FHC of 0.98 (95% CI: 0.96–0.99) and PFD of 0.94 (95% CI: 0.90–0.96) in abnormal cases. DDHnet achieved a sensitivity of 90.56%, specificity of 100%, accuracy of 98.64%, positive predictive value (PPV) of 100%, and negative predictive value (NPV) of 98.44% for the diagnosis of DDH. For the measurement task on the US device, DDHnet took only 1.1 seconds to operate and complete, whereas the experienced senior expert required an average 41.4 seconds.ConclusionsThe proposed DDHnet demonstrate state‐of‐the‐art performance for all four indicators of DDH diagnosis. Fast and highly accurate DDH diagnosis is achievable through DDHnet, and is accessible under constrained computational resources.
Nasal mucociliary clearance after extremely low frequency by scintigraphic and histopathologic evaluation
Authors: Aydinbelge‐Dizdar Nur , Akbulut Aylin , Koca Gokhan , Yumusak Nihat , Canseven Kursun Ayse Gulnihal , Billur Deniz , Korkmaz Meliha 
Published: November 2022

ObjectiveTo investigate the effect of exposure to extremely low‐frequency magnetic fields (ELF‐MFs) on nasal mucociliary clearance (MCC) by rhinosintigrapic and histopathological evaluation.Materials and MethodsThe rats were separated into three groups according to ELF‐MFs intensity and control group. The exposure groups were standardized for the ELF‐MFs of 1, 1.5, and 2 mT emitted by 3 Helmholtz coils for 4 h/day for 30 days. Rhinoscintigraphy was performed to measure nasal MCC. The nasal tissues were examined for edema, inflammation, hyperemia, necrosis, ciliary loss, goblet cell density, and fibroblast proliferation. The data were evaluated statistically (p < 0.05).ResultsNasal mucociliary clearance rates (NMCR) were calculated as 33.13 ± 5.91% in control, 27.78 ± 4.7% in 1 mT, 22.67 ± 5.43% in 1.5 mT, and 18.11 ± 6.33% in 2 mT. NMCR were decreased with increasing ELF‐MFs, in 1.5 and 2 mT groups (p < 0.05) compared to control. Nasal mucociliary transport rate (NMTR) values were found to be 2.17 ± 0.33 mm/min in control, 1.82 ± 0.32 mm/min in 1 mT, 1.46 ± 0.34 mm/min in 1.5 mT and 1.24 ± 0.29 mm/min in 2 mT. NMTR was decreased in the groups exposed to 1.5 and 2 mT (p < 0.05) compared to control. The edema, hyperemia, inflammation, ciliary loss, and goblet cell density were statistically significant differences between control and groups exposed to 1.5 and 2 mT (p < 0.05).ConclusionOur rat model has shown nasal mucosa damage and decreased NMCR and NMTR by rhinoscintigraphy as ELF‐MFs intensity increases. It may be detrimental to nasal mucosa mucociliary function depending on the ELF‐MFs intensity.Level of EvidenceN/A Laryngoscope, 133:2081–2089, 2023
Gradient estimate for asymptotically regular elliptic equations of double phase with variable exponents
Authors: Liang Shuang , Zheng Shenzhou 
Published: November 2022

AbstractWe devote this paper to the proof of a regularity result for the solutions of asymptotically regular elliptic equations with ‐growth. By approximating the solutions of asymptotically regular problems with the solutions of regular problems based on a new perturbation method while the gradients of solutions close to infinity, we derive an interior Calderón–Zygmund estimate.
Thermal/Near‐Infrared Light Dual‐Responsive Reconfigurable and Recyclable Polythiourethane/CNT Composite with Simultaneously Enhanced Strength and Toughness
Authors: Zhao Chunrui , Yue Huimin , Huang Miaoming , He Suqin , Liu Hao , Liu Wentao , Zhu Chengshen , Jiang Lei 
Published: November 2022

AbstractThermoset polymers cross‐linked by dynamic covalent bonds are recyclable and reconfigurable based on solid‐state plasticity, resulting in less waste and environmental pollution. However, most thermoset polymers previously reported show thermal‐responsive solid‐state plasticity, depending much on external conditions and not allowing for local shape modulation. Herein, the isocyanate modified carbon nanotubes (CNTs‐NCO) are introduced into the polythiourethane (PCTU) network with multiple dynamic covalent bonds by in situ polymerization to prepare the composite with thermal/light dual‐responsive solid‐state plasticity, reconfigurability, and recyclability. The introduction of CNTs‐NCO simultaneously strengthens and toughens the PCTU composite. Moreover, based on the photothermal properties and light‐responsive solid‐state plasticity, the PCTU/CNTs composite or bilayer sample can achieve complex permanent shape by locally precise shape regulation without affecting other parts. This work provides a simple and reliable method for preparing high‐performance polymer composite with light‐responsive solid‐state plasticity, which may be applied in the fields of sensing and flexible electronics.
Practically Defined Off‐State Dyskinesia Following Repeated Intraputamenal Glial Cell Line–Derived Neurotrophic Factor Administration
Authors: Lloyd Katherine , Lawton Michael , Whone Alan 
Published: November 2022

ABSTRACTBackgroundWe recently showed that by employing an enhanced drug‐delivery approach, repeated administration of glial cell line–derived neurotrophic factor (GDNF) can produce a spatially distributed increased 18F‐DOPA positron emission tomography (PET) uptake, suggesting sprouting of dopaminergic terminals throughout the putamen structure. Despite this, we failed to prove a significant measurable clinical response. Since, however, we have identified a subject demonstrating a temporal relationship between repeated GDNF infusions and dyskinesia arising in the practically defined off (pracoff) state.ObjectivesTo describe the development of pracoff dyskinesia across our study population and consider its utility as an indicator that trophic factor–induced terminal sprouting can affect enhanced endogenous dopamine levels.MethodsThis was a blinded retrospective analysis of videotaped motor assessments at eight weekly study visits. Dyskinesia in the pracoff and supramaximal on state were rated using the Clinical Dyskinesia Rating Scale. Logistic regression was employed to explore the predictors of pracoff dyskinesia. Generalized estimated equations were used to estimate the cumulative effect of repeated GDNF infusions.ResultsMild–moderate choreiform dyskinesia in the pracoff state were seen in 47 assessments in 17 (n = 41) subjects. During the 18‐month timeframe, each subsequent 8‐week period of receiving GDNF increased the risk of demonstrating pracoff state dyskinesia by 34% (odds ratio [OR], 1.34 (95% confidence interval [CI], 1.20, 1.50); P < 0.001). An increasing supramaximal on dyskinesia score (OR, 1.17 [95% CI, 1.07, 1.30]; P = 0.001) also increased the likelihood of pracoff dyskinesia at that visit.ConclusionsWe report the first description of increasingly prevalent pracoff‐state dyskinesia developing during the course of a trophic factor study. This may provide a surrogate marker that GDNF can enable recovery of endogenous dopamine release even in advanced Parkinson's disease. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
On estimation of the optimal parameter of the modulus‐based matrix splitting algorithm for linear complementarity problems on second‐order cones
Authors: Li Zhizhi , Zhang Huai 
Published: November 2022

AbstractThere are many studies on the well‐known modulus‐based matrix splitting (MMS) algorithm for solving complementarity problems, but very few studies on its optimal parameter, which is of theoretical and practical importance. Therefore and here, by introducing a novel mapping to explicitly cast the implicit fixed point equation and thus obtain the iteration matrix involved, we first present the estimation approach of the optimal parameter of each step of the MMS algorithm for solving linear complementarity problems on the direct product of second‐order cones (SOCLCPs). It also works on single second‐order cone and the non‐negative orthant. On this basis, we further propose an iteration‐independent optimal parameter selection strategy for practical usage. Finally, the practicability and effectiveness of the new proposal are verified by comparing with the experimental optimal parameter and the diagonal part of system matrix. In addition, with the optimal parameter, the effectiveness of the MMS algorithm can indeed be greatly improved, even better than the state‐of‐the‐art solvers SCS and SuperSCS that solve the equivalent SOC programming.
Effects of interfaces and ordered microstructures on thermal properties of graphene flakes/polyethylene composites
Authors: Liu Guanjun , Zhang Xin , Yang Zhongnian , Wang Lu , Yang Fan , Wang Rongguo 
Published: November 2022

AbstractThe lightweight type IV hydrogen storage tanks put forward higher requirements for the thermal properties of the polymer liners. To improve the thermal properties, graphene flakes (GFs) were used as fillers to reinforce high‐density polyethylene (HDPE). The effects of the interfaces between GFs and polymer matrix and the ordered microstructures on the thermal properties of composites were discussed. The results showed that the ordered arrangement of the composite microstructures can significantly improve its thermal conductivity (kc). At 0.5 wt% GFs loading, the ordered composite kc reached 6.052 W/(m K), corresponding to 11.8 times that of unoriented pure HDPE. The effect of interfaces on kc was qualitatively analyzed by scratching GFs on the cross‐section of the composites. Although GFs form continuous networks with high kc in the polymer matrix, the interface defects between GFs and HDPE matrix lead to increased interfacial thermal resistance at high GFs concentrations. Therefore, the thermal enhancement coefficient of the composites decreases with the increase in GFs concentration. Moreover, mixing GFs can increase the initial thermal degradation temperature of the composites by 15.9 °C and the Vicat softening point by 1.6 °C. This work will provide an essential reference for the application of polymers in type IV tanks.