bluuebunny/crossref_metadata_2025_split huggingface dataset:
Miasis cutánea. A propósito de un caso
Authors: Amaya-González María Luisa , Ruz-Zafra María Aurora , Ruiz-Cantero Alberto 
Published: April 2022

Las miasis son un parasitismo producido por larvas de dípteros que, de forma obligatoria o accidental, necesitan alimentarse de tejidos vivos o muertos. Presentamos a un paciente de 75 años con elefantiasis crónica. El paciente vivía en un área rural y tenía bajo nivel socioeconómico. No había viajado recientemente a ningún país subtropical. Analizando el caso, y según el diagnóstico etiológico, concluimos que el paciente presentaba una infestación por Calliphora spp.
Shock obstructivo secundario a tromboembolismo pulmonar y neumotórax simultáneos: utilidad de la ecografía clínica
Authors: Turbau-Valls Miquel , Serés Montserrat , Higa Leopoldo , Moliné Antoni , Álvarez Jesús Andrés 
Published: April 2022

El paro cardíaco supone un reto diagnóstico y terapéutico en los servicios de Urgencias. La ecografía clínica a pie de cama puede ayudar al urgenciólogo en la toma de decisiones de manera decisiva. Presentamos el caso de una paciente que evoluciona a actividad eléctrica sin pulso presentando un tromboembolismo pulmonar masivo y un neumotórax simultáneos, ambos potencialmente responsables de dicho desenlace. La ecografía clínica realizada durante las maniobras de reanimación permitió discernir qué patología era la responsable y establecer un tratamiento dirigido que contribuyó a la evolución favorable de la paciente.
A SCS-CN TECHNIQUE FOR GEOSPATIAL ESTIMATION OF RUNOFF PEAK DISCHARGE IN THE KUBANNI DRAINAGE BASIN, ZARIA, NIGERIA
Authors: Ezenwa K. O. , Iguisi E. O. , Yakubu Y. O. , Ismail M. 
Published: April 2022

The problem of soil loss is becoming widespread due to increasing unwholesome land use practices and population pressure on limited landscape. This study employed the integration of satellite imageries, rainfall and soil data and modern GIS technology to estimate runoff peak discharge in the Kubanni drainage basin. Some of the contributions of this study include the determination of the Hydrologic Soil Group (HSG) and Soil Conservation Service Curve Number (SCS CN) for the Kubanni drainage basin with a view to investigating runoff peak discharge using geospatial technology. Satellite images of Landsat OLI for February, July and November 2019, rainfall data from 2014 to 2018, soil data and SRTM DEM of 30-meter resolution were utilized for the study. A maximum likelihood supervised classification method was adopted in processing the satellite images to determine the Land Use and Land Cover (LULC) classes for the Kubanni drainage basin landscape. The LULC classes for the study area include built up area, water, vegetation, farmland and bare land. The SCS CN values for Goruba, Maigamo, Tukurwa and Malmo sub basins were discovered to be 79.72, 76.51, 71.47 and 66.00 respectively. The runoff peak discharges for the Kubanni drainage basin was found to be , , and for the years 2014, 2015, 2016, 2017 and 2018 respectively. The study has demonstrated the viability of adopting the SCS CN technique, satellite images, rainfall data and geospatial tools for the estimation of runoff peak discharge in the Kubanni drainage basin.
IN-VITRO REGENERATION OF MULTIPLE SHOOTS FROM APICAL MERISTEMS OF COWPEA (Vigna unguiculata L. (WALP) USING DIFFERENT GENOTYPES (LOCAL AND IMPROVED) AND MEDIA COMPOSITIONS
Authors: Bala Isah 
Published: April 2022

Organogenesis in-vitro was evaluated in explants derived from shoot apices of four cowpea varieties cultured on Murashige and Skoog (MS) basal medium. To evaluate the response of the cowpea genotypes to in vitro regeneration, seedlings were drived from zygotic embryos excised from surface sterilized seeds after two weeks of culture on MS basal medium + vitamins supplement with 30% sucrose. To regenerate multiple shoots, apices of the in vitro seedlings with average length of 1cm were excised and cultured on MS supplemented with 0.5, 1.0 or 1.5mg/L 6-Benzylamino purine(BAP) with or without 0.1mg/L α-naphthaleneacetic acid (NAA) for six weeks. The highest shoot number was recorded with IT99k-573-2-1 and Danilla and shoot length was highest in Kanannado, IT04k-33-2-1and Danilla indicating that Danilla responded well to in vitro regeneration. To optimise the production of multiple shoots the effects of different concentratios (0.5, 1.0 and 1.5mg/L) of 6-benzyaminopurine (BAP) with or without 0.1mg/L α-naphthaleneacetic acid on the number of responding explant, number of multiple shoot produced and length of the shoots were tested. after six weeks of culture, the percentage of responding shoot apices was highest on media supplemented with 1.5mg/L BAP with and without 0.1mg/L NAA.The number of responding apices decreasing with decrease in the concentration of BAP. Maximum number of multiple shoots and the highest mean shoot length were also obtained when MS was supplemented with 1.5mg/L BAP with and without 0.1mg/L NAA.
PENYULUHAN DAN PELATIHAN CARA PEMBUATAN PUPUK MIKROBA PADA MASYARAKAT DI MEDAYU UTARA SURABAYA
Authors: Moenandar Siswanto , L. Urip Widodo  , Dwi Sukma Donoriyanto  , Isna Nugraha  
Published: April 2022

Kebutuhan akan pupuk mikroba yang semakin meningkat dikarenakan harga pupuk kimia di pasaran yang membumbung harganya. Sehingga teknologi pembuatan pupuk dengan bahan dasar dari mikroba harus ditingkatkan baik dari segi kualitas maupun kuantitas. Kelurahan Medayu Utara XIV RT 4 RW 12 Medokan Ayu Kecamatan Rungkut berjarak sekitar 29 menit dari pusat kota Surabaya. Kelurahan tersebut merupakan kelurahan yang padat penduduk dan terdiri dari multi daerah, yaitu daerah yang mata pencaharian penduduknya meli-puti wiraswasta, buruh, pedagang, pegawai swasta dan lain-lain. Berdasarkan hasil wawancara tim, kondisi lingkungan banyak sampah organik maupun anorganik dan masyarakat mulai menerapkan kembali pertanian organik sebagai pertanian alami yang biasa disebut sebagai pertanian yang ramah lingkungan. Penggunaan pupuk mikroba pada saat ini makin dirasakan penting untuk mengembalikan produktivitas lahan yang kian menurun. Pupuk hayati merupakan mikroba hidup yang diberikan ke dalam tanah, jenis pupuk tersebut sering juga disebut sebagai pupuk mikroba. Melihat kondisi ini, tim pengabdian dengan berkoordiasi dengan pejabat setempat melaksakan kegiatan penyuluhan dan pelatihan cara memperbanyak pupuk mikroba yang dapat bermanfaat bagi masyarakat Kelurahan Medokan Ayu untuk memanfaatkan pupuk mikroba sebagai pengganti pupuk kimia sehingga bisa menghemat perekonomian rumah tangga. Rangkaian kegiatan pengabdian masyarakat ini dapat meningkatkan pengetahuan, motivasi, dan keterampilan masyarakat dalam pembuatan dan cara memperbanyak pupuk mikroba di Kelurahan Medokan Ayu Kecamatan Rungkut Kota Surabaya. Dengan diadakan kegiatan penyuluhan dan pelatihan pembuatan pupuk mikroba akan menambah pendapatan masyarakat setempat, mengurangi pengeluaran belanja pupuk, dan apabila produksi pupuk sudah berlebih maka bisa dijual menjadi sumber pendapatan baru serta mempertimbangkan aspek kesehatan dan kelestarian alam menjadikan pupuk mikroba sebagai salah satu alternatif pupuk yang berkelanjutan.
The Effect of Nutrition Education with Monopoly and Leaflet on The Nutritional Knowledge Levels and Consumption Pattern Among 5th Grade Elementary School Students in Surabaya
Authors: Nurmalya Kardina Rizki , Ayu Rengganis Nimas , Kamariyah Nurul 
Published: April 2022

In this era, many school-age children have unbalanced and unhealthy eating behaviors. Low nutritional knowledge levels cause the issues. This paper analyzes the differences in nutritional knowledge levels and consumption patterns before and after nutrition education with monopoly media and leaflets among 5th-grade elementary school students in Surabaya. The research method used a quasi-experimental design. The population was 170 5th grade elementary school students at SDN I and SDN II Surabaya. In addition, this study utilized probability sampling with a sample of 90 students. Next, data analysis used the Mann-Whitney and Wilcoxon tests with a significant level of α 0.05. There were differences in nutritional knowledge levels before and after nutrition education with monopoly media in both schools (p=0.000). Meanwhile, there were no differences in nutritional knowledge levels before and after nutrition education with leaflet media (SDN I Surabaya p=0.073 and SDN II Surabaya p=0.052). In addition, both schools had differences in consumption patterns before and after nutrition education with monopoly media (p=0.000). However, there were no differences in consumption patterns before and after nutrition education with leaflet media (at SDN I Surabaya p=0.301 and SDN II Surabaya p=0.307). Nutrition education with monopoly media is more effective in improving nutritional knowledge levels and consumption patterns than leaflet media in 5th-grade students. Further research could compare monopoly with other EGT (educational game tools, such as snakes and ladders nutrition or nutrition puzzle.
The Survey of Community Anxiety During the Emergency Care (Community Activity Restriction Enforcement) Period
Authors: Puspitaningsih Dwiharini , Laga Hadi Kusuma Yudha , Mawaddah Nurul 
Published: April 2022

In the few months, increased Covid-19 cases in Indonesia forced the government to Emergency CARE (Community Activity Restriction Enforcement) program in Java-Bali. In addition to COVID-19 impact, Emergency CARE also adds anxiety to the community. This paper aims to analyze community anxiety during the Emergency CARE period. It was a descriptive-analytic study with a survey method. The variable was community anxiety during the Emergency CARE period. Sampling used non-probability sampling with convenience sampling technique with 165 respondents scattered in Java and Bali. In addition, this study used the Zung Self-Rating Anxiety Scale (ZSAS) instrument. The results showed community anxiety was mostly respondents (78%) within normal limits, 16% experienced mild, and 6% had moderate anxiety. In conclusion, there is no community anxiety during the Emergency CARE period. However, the implementation of Emergency CARE potentially causes community anxiety because it has an average anxiety score that exceeds the minimum anxiety score based on the ZSAS instrument assessment. It is necessary to improve information, education, and communication (IEC) regarding preventing Covid-19 transmission and properly handling psychosocial problems in society to lead to a strong family during the pandemic. Furthermore, This survey could be a policy recommendation to follow-up in overcoming community psychosocial problems due to the Emergency CARE program.
Filosofía de la mente y prueba de los estados mentales: Una defensa de los criterios de “sentido común”
Authors: González Lagier Daniel 
Published: April 2022

<span lang="es">La prueba de los hechos psicológicos o estados mentales plantea dificultades de carácter ontológico (¿existen realmente hechos mentales, distintos de los hechos físicos?), epistemológico (¿cómo puedo conocer los estados mentales de los demás?) e ideológico (¿son jurídicamente relevantes?). Una parte de la doctrina y de la jurisprudencia ha dicho que, en realidad, los estados mentales no son -o no deben ser tratados como- “hechos” propiamente, por lo que no se prueban (esto es, no se demuestra que hayan ocurrido o hayan existido), sino que para el Derecho son entidades ficticias que se imputan o adscriben a partir de ciertos criterios normativos. Este escepticismo contrasta con el hecho de que todos atribuimos con frecuente éxito estados mentales a los demás y conseguimos adaptar y coordinar nuestra conducta a la de los otros gracias a esas atribuciones. Sabemos atribuir estados mentales, pero no sabemos cómo lo hacemos. En este trabajo trato de analizar qué luz puede arrojar la filosofía de la mente (en particular, las teorías acerca del llamado “problema de las Otras Mentes”) a la prueba de los hechos psicológicos en el Derecho.</span>
Frequency of Metabolic syndrome in Patients with Shoulder Pain
Authors: SARGIN Serdar , ŞAHİN Nilay , KARAHAN Ali Yavuz , AYDIN Zafer 
Published: April 2022

Objectives: Shoulder pain is a common cause of disability. There are few studies in the literature linking Metabolic Syndrome (MetS) with shoulder pain and shoulder pathologies. This study aims to determine the frequency of metabolic syndrome in patients with shoulder pain; and whether there was a difference between the two groups in terms of severity and characteristics of shoulder pain.
Methods: In this prospective cross-sectional study, the target population consisted of subjects aged 18 years or older applying to outpatient clinic with shoulder pain. Detailed shoulder examinations were performed. Waist-to-hip ratio and body mass index were calculated. Blood pressures were measured. Fasting blood glucose and lipids level were recorded. A Visual Analogue Scale for current pain was applied.
Results: MetS was diagnosed in 44 of 104 patients. The most common shoulder problems of patients with MetS; were partial tear of rotator cuff muscles, frozen shoulder, and supraspinatus tendinitis in 5 (55.6%), 16 (32.3%), and 10 (51.6%) of the patients, respectively. ROM limitation was found to be statistically significantly higher in patients with MetS in internal and external rotation and passive abduction movements. VAS scores were higher in patients with Mets. While the difference in VAS scores with active movement and at rest was statistically significant, the difference in VAS score in night pain was not statistically significant.
Conclusion: We concluded that there is a clear relationship between shoulder pain and MetS. Awareness of such association may allow early diagnosis of MS and early institution of measures to avoid its results.
Personalized Disease Monitoring in Pediatric Onset Multiple Sclerosis Using the Saliva Free Light Chain Test
Authors: Ganelin-Cohen Esther , Tartakovsky Evgeny , Klepfish Ely , Golderman Sizilia , Rozenberg Ayal , Kaplan Batia 
Published: April 2022

BackgroundDevelopment of new safe methods of monitoring disease activity in the pediatric onset multiple sclerosis (POMS) is a challenging task, especially when trying to refrain from frequent MRI usage. In our recent study, the saliva immunoglobulin free light chains (FLC) were suggested as biomarkers to discriminate between remission and active MS in adults.ObjectivesTo assess utility of saliva FLC measurements for monitoring disease activity in POMS.MethodsWe used semiquantitative Western blot analysis to detect immunoreactive FLC monomers and dimers and to calculate the intensity of their bands. Statistical tests included Firth logistic regression analysis suitable for small sample sizes, and Spearman’s non-parametric correlation.ResultsIn naive POMS patients, the saliva levels of FLC in relapse were significantly higher than those in remission. Significant correlation was found between FLC levels (monomers, dimers or both) and the load of enhanced lesions in MRI scans. FLC levels may be reduced under treatment, especially as result of corticosteroids therapy. Follow-up of individual patients showed the correspondence of changes in the FLC levels to MRI findings.ConclusionsOur results show the potential of the non-invasive saliva FLC test, as a new tool for monitoring the disease activity in POMS.
The Associations of rs1799724 and rs361525 With the Risk of Ankylosing Spondylitis Are Dependent on HLA-B27 Status in a Chinese Han Population
Authors: Sheng Nan , Gao Yingying , Li Hui , Wang Wenwen , Geng Linyu , Zhang Bo , Huang Qiang , Wang Xueqin , Sun Lingyun 
Published: April 2022

ObjectivesHuman leucocyte antigen B27 (HLA-B27) is an important biomarker for ankylosing spondylitis (AS). However, delay in the diagnosis of AS is still common in clinical practice. Several single nucleotide polymorphisms (SNPs) in the coding gene of tumor necrosis factor alpha (TNFα) have been reported to be AS susceptibility loci. Our aim was to explore whether SNPs in TNFα could be used to improve the performance of HLA-B27 for predicting AS.MethodsFive SNPs (rs1799964, rs1800630, rs1799724, rs1800629, and rs361525) spanning TNFα were genotyped by qPCR-Invader assay in 93 AS patients and 107 healthy controls for association analysis and linkage disequilibrium (LD) analysis. Random forest algorithm was utilized to construct the predictive classifiers for AS. HLA-B was genotyped by PCR-sequence-based typing in a subset of the HLA-B27-positive subjects (38 AS patients and 5 healthy controls).ResultsThe T allele of rs1799724 was verified to significantly increase the risk of AS (OR = 4.583, p &lt; 0.0001), while the A allele of rs361525 showed an association with the reduced AS risk (OR = 0.168, p = 0.009). In addition, the rs1799964T-rs1800630C-rs1799724T-rs1800629G-rs361525G haplotype was significantly associated with a higher risk of AS (p &lt; 0.0001). The optimal set of variables for classifiers to predict AS only consisted of HLA-B27. Strong associations with HLA-B27 status were found in both rs1799724 (p &lt; 0.0001) and rs361525 (p = 0.001), and all the analyzed HLA-B27-positive subjects carried HLA-B*27:04 or HLA-B*27:05.ConclusionIn the Chinese Han population, the minor allele T of rs1799724 could increase the risk of AS, while the minor allele A of rs361525 protects individuals from AS. However, the contributions of rs1799724 and rs361525 to AS risk were dependent on HLA-B27 status, suggesting the importance of taking the independence and specificity into consideration in AS susceptibility loci studies.
Characteristics and Comparison of Adverse Events of Coronavirus Disease 2019 Vaccines Reported to the United States Vaccine Adverse Event Reporting System Between 14 December 2020 and 8 October 2021
Authors: Zou Chenyu , Xue Xiangzhong , Qian Jingjing 
Published: April 2022

BackgroundThis study assessed and compared the frequency and type of adverse events (AEs) of the Pfizer-BioNTech, Moderna, and Janssen coronavirus disease 2019 (COVID-19) vaccines reported in the Vaccine Adverse Event Reporting System (VAERS).MethodsA retrospective analysis examined VAERS reports between 14 December 2020 and 8 October 2021 and focused on AE reports related to COVID-19 vaccines and AE outcomes [e.g., emergency room (ER) visits after being vaccinated, hospitalization, prolongation of existing hospitalization, life-threatening events, disability, birth defect, and death]. Reporting odds ratios (RORs) and Breslow-Day statistics were used to compare AE reporting between COVID-19 and non-COVID vaccines and between individual COVID-19 vaccines.ResultsA total of 604,157 AEs of COVID-19 vaccines were reported, including 43.51% for the Pfizer-BioNTech vaccine, 47.13% for the Moderna vaccine, and 9.12% for the Janssen COVID-19 vaccine. About 12.56% of patients visited ER after being vaccinated, 5.96% reported hospitalization, and 1.52% reported life-threatening events. Among the number of death cases (n = 7,674; mean age = 73), 2,025 patients (26.39%) had hypertension and 1,237 (16.12%) patients had cancer. RORs between COVID-19 vaccines and non-COVID vaccines identified increased ROR in ER visits, hospitalization, and life-threatening events. The results of the Breslow-Day statistics indicated heterogeneities between the disproportionality of reports across the four serious AE outcomes (i.e., ER visits, hospitalization, life-threatening events, and disability) between individual COVID-19 vaccines.ConclusionMost current VAERS reports showed that the most commonly reported AEs of COVID-19 vaccines were mild. Cases with a mortality outcome tended to occur in older adults with underneath conditions. Close ongoing surveillance in the safety of COVID-19 vaccines is critical and will inform the use of individual COVID-19 vaccines. Given the known limitations associated with the passive spontaneous reporting system, such as VAERS, our findings need to be further assessed and verified through longitudinal, large healthcare data systems.
Structural and Functional Alterations of Substantia Nigra and Associations With Anxiety and Depressive Symptoms Following Traumatic Brain Injury
Authors: Gao Liang , Xue Qiang , Gong Shun , Li Gaoyi , Tong Wusong , Fan Mingxia , Chen Xianzhen , Yin Jia , Song Yu , Chen Songyu , Huang Jingrong , Wang Chengbin , Dong Yan 
Published: April 2022

BackgroundsAlthough there are a certain number of studies dedicated to the disturbances of the dopaminergic system induced by traumatic brain injury (TBI), the associations of abnormal dopaminergic systems with post-traumatic anxiety and depressive disorders and their underlying mechanisms have not been clarified yet. In the midbrain, dopaminergic neurons are mainly situated in the substantia nigra (SN) and the ventral tegmental area (VTA). Thus, we selected SN and VTA as regions of interest and performed a seed-based global correlation to evaluate the altered functional connectivity throughout the dopaminergic system post-TBI.MethodsThirty-three individuals with TBI and 21 healthy controls were recruited in the study. Anxiety and depressive symptoms were examined by the Hospital Anxiety and Depression Scale. All MRI data were collected using a Siemens Prisma 3.0 Tesla MRI system. The volume of SN and the global functional connectivity of the SN and VTA were analyzed.ResultsIn the present study, patients with TBI reported more anxiety and depressive symptoms. More importantly, some structural and functional alterations, such as smaller SN and reduced functional connectivity in the left SN, were seen in individuals with TBI. Patients with TBI had smaller substantia nigra on both right and left sides, and the left substantia nigra was relatively small in contrast with the right one. Among these findings, functional connectivity between left SN and left angular gyrus was positively associated with post-traumatic anxiety symptoms and negatively associated with depressive symptoms.ConclusionsThe TBI causes leftward lateralization of structural and functional alterations in the substantia nigra. An impaired mesocortical functional connectivity might be implicated in post-traumatic anxiety and depression.
The Development and Validation of a Nomogram Incorporating Clinical, Pathological, and Therapeutic Features to Predict Overall Survival in Patients With Penile Cancer: A SEER-Based Study
Authors: Li Ruidan , Cheng Ke , Wei Zhigong , Liu Zheran , Peng Xingchen 
Published: April 2022

ObjectiveThis study aimed to investigate the prognostic factors of penile cancer and establish a comprehensive predictive model for clinical application.MethodsA total of 581 patients from the Surveillance, Epidemiology, and End Results (SEER) program (2000–2018) were used to develop the prognostic model. The multivariate Cox proportional hazards regression was performed to identify independent prognostic factors to develop the nomogram. The performance of this model was validated internally by a cohort with 143 patients from the SEER database and validated externally by a cohort with 70 patients from the West China Hospital, Sichuan University (2010–2020).ResultsAge, marital status, size of the primary lesion, primary tumor (T), regional lymph nodes status, distant metastasis (M), and the surgery of regional lymph node (LND) were the independent prognostic factors for overall survival (OS) and were incorporated in the prognostic model. The prognostic nomogram showed a good risk stratification ability for OS in the development cohort, internal validation cohort, and external validation cohort.ConclusionThis study incorporates the clinical, pathological, and therapeutic features comprehensively to develop a novel and clinically effective prognostic model for patients with penile cancer.