bluuebunny/crossref_metadata_2025_split huggingface dataset:
Allowing access to parents/caregivers into COVID-19 hospitalization areas does not increase infections among health personnel in a pediatric hospital
Authors: De la Rosa-Zamboni Daniela , Adame-Vivanco María José , Luque-Coqui Mercedes , Jaramillo-Esparza Carlos Mauricio , Ortega-Riosvelasco Fernando , Reyna-Trinidad Irineo , Guerrero-Díaz Ana Carmen , Ortega-Ruiz Sergio Gabriel , Saldívar-Salazar Sergio , Villa-Guillen Mónica , Nieto-Zermeño Jaime , Bonilla-Pellegrini Sergio René , Jamaica Balderas Lourdes María del Carmen 
Published: September 2022

BackgroundAt the beginning of the current COVID-19 pandemic, it became critical to isolate all infected patients, regardless of their age. Isolating children has a negative effect on both, them and their parents/caregivers. Nevertheless isolation was mandatory because of the potential risk that visitation might have on COVID-19 dissemination mostly among health personnel.MethodsFrom the starting of the COVID-19 pandemic in our pediatric hospital visits were forbidden. This 2 months period (April–May) was called P1. In June parents were allowed to visit (P2), under a visiting protocol previously published. Hospital workers were monitored for the presence of COVID-19 symptoms and tested for the infection when clinically justified. The positivity proportion and the relative risk (RR) of COVID-19 among the health personnel between periods were calculated. The caregivers were also followed up by phone calls.ResultsSince April 2020 to November 2020, 2,884 health personnel were studied for 234 days, (318,146 workers days). Although the COVID-19/1,000 health personnel days rate decreased from one period to another (1.43 vs 1.23), no statistically significant differences were found. During P1, 16 patients with COVID-19 were treated. During the follow up none of the family members were infected/symptomatic in P1, while in P2, 6/129 (4.65%) were symptomatic or had a positive test. All of them initiated between 2 and 4 days after the patient's admission. As they also had some other infected family members it was not possible to ensure the source of infection. There were no statistically significant differences in the RR of COVID-19 in health personnel, (RR 1, 95% CI 0.69–1.06, p = 0.162).ConclusionsWhen safely implemented, allowing parents/caregivers to spend time with their hospitalized COVID-19 children does not increase the contagion risk for hospital workers or among themselves.
Using proton pump inhibitors increases the risk of hepato-biliary-pancreatic cancer. A systematic review and meta-analysis
Authors: Zhou Wence , Chen Xinlong , Fan Qigang , Yu Haichuan , Jiang Wenkai 
Published: September 2022

Background: More and more studies are focusing on the adverse effects and damage caused by PPI abuse, we carried out a systematic review and meta-analysis for assessing whether the proton pump inhibitor (PPI) leads to hepato-biliary-pancreatic cancer.Methods: PubMed, EMBASE and Web of Science were searched until 1 July 2022, 25 studies (17 case-control and 8 cohort studies; 2741853 individuals) included in this study. Pooled Odd Ratios (ORs) were used for random effect models. Sensitivity analysis and dose-response analysis, subgroup analysis were all conducted.Results: The aggregate OR of the meta-analysis was 1.69 (95% confidence interval (CI): 1.42–2.01, p = 0.01) and heterogeneity (I2 = 98.9%, p &lt; 0.001) was substantial. According to stratified subgroup analyses, the incidence of hepato-biliary-pancreatic cancer was associated, expect for study design, study quality and region. Risk of hepato-biliary-pancreatic cancer is highest when people is treated with normal doses of PPI. The risks decrease and become insignificant when the cumulative defined daily dose (cDDD) increases.Conclusion: The use of PPI may be associated with an increased risk of hepato-biliary-pancreatic cancer. Hence, caution is needed when using PPIs among patients with a high risk of hepato-biliary-pancreatic cancer.
Factors associated with anti-retroviral therapy adherence among patients living with HIV during the COVID-19 pandemic: A cross-sectional study
Authors: Suryana Ketut , Suharsono Hamong , Indrayani Agung Wiwiek , Wisma Ariani Luh Nyoman Arya , Putra Wayan Wahyu Semara , Yaniswari Ni Made Dwita 
Published: September 2022

BackgroundThe coronavirus disease (COVID-19) pandemic causes fear and anxiety symptoms on some vulnerable populations such as patients living with human immunodeficiency virus (HIV) (PLWH). Physical distancing (during consultation in the clinic) and isolation restrictions will likely have a negative impact on/disruption to all care continuum services of HIV diseases although healthcare services and access to anti-retroviral therapy (ART) have continued to operate.ObjectiveTo investigate the factors associated with ART adherence among PLWH during the COVID-19 pandemic.MethodologyA cross-sectional study was conducted on 324 PLWH who had been on ART for at least 6 months between June 2020 and January 2021. A semi-structured questionnaire was used to interview participants to collect data on sociodemographic characteristics and other factors.ResultsOf 324 PLWH taking ART, 264 (81.48%) had high adherence (≥95%) and 60 (18.52%) had low adherence (&lt; 95%). Factors independently associated with high ART adherence were employment status (adjusted odds ratio (AOR): 0.030, 95% confidence interval (CI): 0.010–0.088; p &lt; 0.001), type of antiretroviral (ARV) (AOR: 3.101, 95% CI: 1.137–8.456; p = 0.027), family support (AOR: 0.157, 95% CI: 0.052–0.475; p = 0.001), the perception that the COVID-19 pandemic negatively impacts the ability to attend clinics (AOR: 7.339, 95% CI: 1.46–36.79; p = 0.015), and the perception that the COVID-19 pandemic negatively impacts the ability to take ART (AOR: 10.611, 95% CI: 2.98–37.72; p &lt; 0.001).ConclusionsDuring the COVID-19 pandemic, factors associated with high ART adherence among PLWH attending the Hospital of Wangaya in Denpasar, Bali, Indonesia were employment status, ART type [non-fixed dose combination (FDC)], family support, and the perception that the COVID-19 pandemic negatively impacts the ability to attend clinics and to take ART.
Common mental disorders during the COVID-19 pandemic in Hong Kong: Age-related differences and implications for dementia risk
Authors: Kwok Jessie O. T. , Yan Rachel W. K. , Kwok Charlotte P. C. , Cheng Gabriel W. H. , Lin Cuichan , Wong Brian H. C. , Cheng Sheung Tak , Lee Allen T. C. , Lam Linda C. W. 
Published: September 2022

BackgroundThe COVID-19 pandemic has imposed a profound negative impact on the mental health and wellbeing of societies and individuals worldwide. Older adults may be more vulnerable to the mental health effects of the pandemic, either directly from the infection itself or indirectly through the preventive measures. However, the existing literature on mental health in the older age groups has not been consistent so far. The aim of this study was therefore to assess the prevalence of common mental disorders (CMD; including depression and anxiety disorders) given their association with dementia risk, and to further examine age-related differences between older (≥60 years old) and younger (18–59 years old) adult's psychological status during the COVID-19 pandemic.MethodThis was a secondary analysis of a cross-sectional survey-study conducted during the second wave of COVID-19 pandemic in Hong Kong. The survey was disseminated through different social media platforms to the general population and included sociodemographic questions, self-reported physical health, and previous encounter with SARS or COVID-19. CMD was the primary outcome and was assessed using the 6-item Kessler Scale. A total of 1030 adults fulfilled inclusion criteria.ResultsThe prevalence of CMD during the pandemic was 16.1%. Compared to younger adults, older adults were significantly less likely to have a CMD (unadjusted OR = 0.07, 95% CI = 0.02–0.30, p &lt; 0.001), with 18.1% of younger adults having CMD compared to 1.6% in the older cohort. Age differences remained significant after controlling for sociodemographic factors, physical health, and previous encounter with SARS or COVID-19 (adjusted OR = 0.12, 95% CI = 0.02–0.57, p = 0.008).ConclusionCommon mental disorders are highly prevalent during the COVID-19 pandemic in Hong Kong, though older adults appeared to be less affected mentally. Present findings highlight the urgent need to implement measures and strategies to mitigate the mental health problems, with particular attention to the younger cohort. Given their association with higher dementia risk, early detection and treatment of depression and anxiety disorders will be of critical importance in providing some relief to the already pressurized dementia burden in the longer term.
Targeting COVID-19 vaccine hesitancy among nurses in Shanghai: A latent profile analysis
Authors: Zhang Enming , Dai Zhengyue , Wang Caifeng , Hu Jiale , Wang Suxing , Zhang Lin , Fang Qiong 
Published: September 2022

ObjectivesThis study aims to clarify the profiles of the psychological antecedents of vaccine hesitancy among Shanghai nurses with a person-centered approach.MethodsA population-based cross-sectional online survey was conducted on Shanghai nurses from July to August 2021 (N = 1,928). In the online survey, participants were asked to report their sociodemographic, the 5C vaccine hesitancy components, their knowledge level of COVID-19 vaccine and vaccination, and the COVID-19 vaccination uptake intention and attention to vaccine news. Latent profile analysis was used to reveal distinct profiles of vaccine hesitancy.ResultsThe results revealed four profiles, including “believers” (68.9%; high confidence and collective responsibility), “free riders” (12.7%; similar characteristics to believers, except for a low collective responsibility), “middlemen” (14.6%; middle in all 5C constructs), and “contradictors” (3.7%; high in all 5C constructs). Compared to believers, middlemen were younger, more likely to be female, childless, less educated, held lower professional titles, had fewer years of nursing service, sometimes or never complied with recommended vaccinations, had satisfactory or poor self-assessed health status, had no work experience during the COVID-19 epidemic, and possessed greater levels of knowledge. Free riders were more likely to work in community health centers and have a lower degree than believers. Contradictors were more likely to work in community health centers, had junior college degrees or lower, and had no work experience during the COVID-19 epidemic than believers. From the highest to the lowest on vaccination intention and attention to vaccine news were believers, then free riders, contradictors, and finally middlemen.ConclusionThis study could aid in the development of personalized vaccination strategies based on nurses' vaccine hesitancy profiles and predictors. In addition to vaccine believers, we identified other three profiles based on their 5C psychological antecedents, emphasizing the significance of establishing tailored vaccination campaigns. Further research into the prevalence of profile structure in other groups of healthcare workers is required.
Pooled prevalence and determinants of informed choice of contraceptive methods among reproductive age women in Sub-Saharan Africa: A multilevel analysis
Authors: Tsega Nuhamin Tesfa , Haile Tsion Tadesse , Asratie Melaku Hunie , Belay Daniel Gashaneh , Endalew Mastewal , Aragaw Fantu Mamo , Tsega Sintayehu Simie , Gashaw Moges 
Published: September 2022

BackgroundDespite the commitments of the government to minimize unintended pregnancy, abortion, and unmet need for contraceptives, as per our search of the literature, there is no study on the pooled prevalence and determinants of informed choice of contraceptive methods in sub-Saharan Africa. Therefore, this study aimed to assess the pooled prevalence and determinants of informed choice of contraceptive methods among reproductive-aged women in sub-Saharan Africa.MethodsThis study was based on the 32 Sub-Saharan African countries Demographic and Health Survey data. A total weighted sample of 65,487 women aged 15–49 was included in the study. The data were cleaned, weighted, and analyzed using STATA Version 14 software. Multilevel logistic regression modeling was used to identify determinants of an informed choice of contraceptive methods. Adjusted odds ratio (AOR) with 95% Confidence Interval (CI) and p-value &lt; 0.05 were used to declare the significant determinants.ResultThe pooled prevalence of informed choice of contraceptive methods among reproductive age (15–49) women in sub-Saharan Africa was 49.47% (95%CI: 44.33, 54.62%) with I2 =99.5%, and variations in range of 19.42 to 78.42%. Women aged 25–34 years old (AOR = 1.26 95%CI: 1.21, 1.32) and 35–49 years (AOR = 1.33 95%CI: 1.27, 1.40), attending primary education (AOR = 1.26, 95% CI: 1.20, 1.32), secondary education (AOR = 1.50, 95% CI: 1.43, 1.58) and higher education (AOR = 2.01, 95% CI: 1.84, 2.19), having media exposure (AOR = 1.12, 95%CI: 1.07, 1.16), utilizing IUD (AOR = 1.98, 95%CI: 1.79, 2.19), injectable (AOR = 1.29, 95%CI: 1.23, 1.36) and implants (AOR = 1.70, 95%CI: 1.61, 1.79), survey year 2016–2020 (AOR = 1.38, 95%CI: 1.31, 1.44), women from lower middle (AOR = 1.25, 95%CI: 1.19, 1.31) and upper middle income level countries (AOR = 1.37, 95%CI: 1.23, 1.53) were associated with increased odds of informed choice of contraceptive methods. While, women who accessed contraceptives from private clinics (AOR = 0.64, 95%CI: 0.61, 0.67), pharmacies (AOR = 0.37, 95%CI: 0.35, 0.40), and others (AOR = 0.47, 95%CI: 0.43, 0.52), women in East Africa (AOR = 0.70, 95% CI: 0.67, 0.73), Central Africa (AOR = 0.52, 95% CI: 0.47, 0.57), and South Africa (AOR = 0.36, 95% CI: 0.32, 0.40) were associated with decreased odds of informed choice of contraceptive methods.ConclusionThe pooled prevalence of informed choice of contraceptive methods in Sub-Saharan Africa is low with high disparities among the countries. Enhancing maternal education and media exposure, providing greater concern for the source of contraceptive methods, and strengthening the economic status of the country are recommended to enhance informed choice of contraceptive methods.
Patient engagement to examine perceptions of perinatal depression screening with the capabilities, opportunities, motivation, and behaviors (COM-B) model
Authors: Tabb Karen M. , Hsieh Wan-Jung , Sung Jung Sun , Hoang Tuyet Mai Ha , Deichen Hansen Megan E. , Lux Emily , Huang Wen-Hao David 
Published: September 2022

BackgroundPerinatal (during pregnancy and up until one year after birth) depression is one of the most common medical complications of pregnancy and is a major public health issue. The common early detection method to identify depression is to systematically administer depression screens to patients during their usual care clinic encounters. This study investigates how prenatal patients perceive depression screening and how screening informs their treatment to meet the specific needs of different racial and ethnic groups within both community and health care settings.MethodsBetween June 2019 and August 2019, semi-structured in-depth interviews were conducted to explore participants' experiences of depression screening with the Edinburgh Postnatal Depression Scale (EPDS). Perinatal women (N = 29) consented to participate in-depth, one-on-one qualitative interviews. Trained patient-researchers (n = 6), women who had previously experienced a perinatal mental health problem, were trained as research team members and facilitated the interviews alongside a research assistant. All interviews were recorded and transcribed verbatim. Data was analyzed with the use of Nvivo12. Thematic network analysis was used to analyze the data.ResultsThrough the in-depth patient engaged qualitative interviews this study uncovered several specific motivators and behaviors related to perinatal depression screening. Using directed content analysis, several themes within a COM-B frame emerged and could be reduced to themes and further divided into two different stages: the depression screening stage and the post-screening stage.ConclusionsThe results of this qualitative study provide information for health care providers to improve, adjust, and assess the process of conducting perinatal depression screening among women. The data also provide information for health care facilities to identify a better screening tool and develop and measure their screening process. These findings are essential to design comprehensive patient-centered screening protocols given the increase in state and federal policies urging universal depression screening.
Long-Term Trend in the Association Between Disaster Damage and Happiness Before and After the Great East Japan Earthquake
Authors: Nagai Masato , Hikichi Hiroyuki , Shiba Koichiro , Kondo Katsunori , Kawachi Ichiro , Aida Jun 
Published: September 2022

Objectives: Disasters change survivors’ living circumstances, which can affect their happiness. We examined the trends in the association between disaster damage and happiness before and after a disaster.Methods: We analyzed 4,044 participants aged ≥65 years who had experienced the Great East Japan Earthquake in 2011. The baseline survey was conducted 7 months before the disaster. Follow-up surveys have been conducted every 3 years. Using a mixed model for repeated measures, we compared the prevalence ratios (PRs) for unhappiness according to the survivors’ level of housing damage, which is a proxy for disaster damage.Results: The unhappiness in participants who suffered severe damage appeared to be higher than in those with no damage in 2010 (multivariate-adjusted PR: 1.18, 95% confidence interval: 0.93–1.48). A higher PR was observed after the earthquake in 2013 (1.34, 0.79–2.28), while there was no difference in 2016 (1.02, 0.53–1.97) and 2019 (1.03, 0.50–2.12).Conclusion: The prevalence of unhappiness in survivors with severe housing damage was higher before the disaster. However, the unhappiness gap between people with and without housing damage converged during the follow-up.
Potential impact of NICE guidelines on referrals from primary care to nephrology: a primary care database and prospective research study
Authors: Sullivan Michael K , Jani Bhautesh Dinesh , Rutherford Elaine , Welsh Paul , McConnachie Alex , Major Rupert W , McAllister David , Nitsch Dorothea , Mair Frances S , Mark Patrick B , Lees Jennifer S 
Published: September 2022

BackgroundNational Institute for Health and Care Excellence 2021 guidelines on chronic kidney disease (CKD) recommend the use of the Kidney Failure Risk Equation (KFRE), which includes measurement of albuminuria. The equation to calculate estimated glomerular filtration rate (eGFR) has also been updated.AimTo investigate the impact of the use of KFRE and the updated eGFR equation on CKD diagnosis (eGFR <60 mL/min/1.73 m2) in primary care and potential referrals to nephrology.Design and settingPrimary care database (Secure Anonymised Information Linkage Databank [SAIL]) and prospective cohort study (UK Biobank) using data available between 2013 and 2020.MethodCKD diagnosis rates were assessed when using the updated eGFR equation. Among people with eGFR 30–59 mL/min/1.73 m2the following groups were identified: those with annual albuminuria testing and those who met nephrology referral criteria because of: a) accelerated eGFR decline or significant albuminuria; b) eGFR decline <30 mL/ min/1.73 m2only; and c) KFRE >5% only. Analyses were stratified by ethnicity in UK Biobank.ResultsUsing the updated eGFR equation resulted in a 1.2-fold fall in new CKD diagnoses in the predominantly White population in SAIL, whereas CKD prevalence rose by 1.9-fold among Black participants in UK Biobank. Rates of albuminuria testing have been consistently below 30% since 2015. In 2019, using KFRE >5% identified 182/61 721 (0.3%) patients at high risk of CKD progression before their eGFR declined and 361/61 721 (0.6%) low-risk patients who were no longer eligible for referral. Ethnic groups ‘Asian’ and ‘other’ had disproportionately raised KFREs.ConclusionApplication of KFRE criteria in primary care will lead to referral of more patients at elevated risk of kidney failure (particularly among minority ethnic groups) and fewer low-risk patients. Albuminuria testing needs to be expanded to enable wider KFRE implementation.
Peran Tongkonan Tallu dalam Kehidupan Bergereja Sebagai Institusi Sosial
Authors: Tatung Windira Lawangan 
Published: September 2022

This study aims to describe that the Tongkonan is one of the important elements in the life of the Toraja people. Tongkonan not only functions as a traditional house but is also referred to as a social institution because in it there are patterns of organization, power, and leadership. Seeing its function, Tongkonan as a culture can shape human behavior for the better. This research was conducted in the Marintang Simbuang area, Mengkendek sub-district, Tana Toraja district. The theoretical studies used are culture and social institutions. As one of the cultures, Tongkonan Tallu has contributed to passing down the basics of life, both in society and in church life. Therefore, the role of Tongkonan Tallu as a culture can direct how humans behave towards life, work, time, nature, and human relationships with each other. AbstrakPenelitian ini bertujuan untuk mendeskripsikan bahwa tongkonan merupakan salah satu elemen penting dalam kehidupan masyarakat Toraja. Tongkonan tidak hanya berfungsi sebagai rumah adat tetapi juga disebut sebagai salah satu institusi sosial, sebab di dalamnya terdapat pola organisasi, kekuasaan, dan kepemimpinan. Melihat fungsinya, tongkonan sebagai salah satu kebudayaan dapat membentuk perilaku manusia menjadi lebih baik. Penelitian ini dilakukan di daerah Marintang Simbuang, kecamatan Mengken-dek, kabupaten Tana Toraja. Adapun kajian teori yang digunakan ialah kebu-dayaan dan institusi sosial. Sebagai salah satu budaya, Tongkonan Tallu telah berkontirubusi dalam mewariskan dasar-dasar dalam kehidupan, baik dalam masyarakat maupun kehidupan bergereja. Oleh karenanya, peran Tongkonan Tallu sebagai suatu kebudayaan dapat mengarahkan bagaimana manusia berperilaku terhadap hidup, karya, waktu, alam, dan hubungan manusia dengan sesamanya.