bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Russian invasion of Ukraine: some readings from Italian newspapers (20 February–5 March 2022)
Authors: Lami Giulia , Sahota Simranjit Kaur 
Published: June 2022

AbstractOver the last two years, the metaphor of war has often been used in Italy when discussing the fight against the pandemic, to describe the restrictions that have been introduced as a result, from lockdown to the Green Pass. Paradoxically, once the state of emergency ended, just as we were on the cusp of the long-awaited return to normality (to ‘peace’ in a sense), Russia's sudden invasion of Ukraine meant that war truly became part of Italians’ lives through the media. In this context, I have analysed the positions taken by the major Italian periodicals (Avvenire, Corriere della Sera, Il Fatto Quotidiano, Il Foglio, La Repubblica, La Stampa, Il Mattino di Napoli, Il Messaggero and Il Tempo di Roma) between 20 February and 5 March. What becomes clear through examination of the main articles is that the themes that would characterise the subsequent Italian debate – from a strategic, humanitarian, political, and economic point of view – were already present in the two weeks from the end of February to the beginning of March 2022.
Scientific knowledge and sexual advocacy: African publics, choiceless citizens and potential confounders
Authors: Raidoo Renugan 
Published: June 2022

AbstractThis article is concerned with science and sexuality, and the possibilities and pitfalls of using the former to change minds about the latter, taking as its main source of data a report released by the Academy of Science of South Africa in 2015,Diversity in Human Sexuality: implications for policy in Africa. I frame the report in terms of co-production – borrowed from science and technology studies – and a theory of publics – taken from literary criticism and queer theory. I first describe how science has played a role in recent queer politics before showing how the report intervenes by appealing to a particularly African public. Thereafter, I describe how the choosing agentive subject disappears in the report’s depiction of the legitimate sexual citizen. Such a framing of citizenship raises several possible problems, some of which I address in the final section. These are described as potential confounders inhibiting the success of the report, preventing effective co-production or the summoning of a public. The article’s goal is not to discredit the report; rather, in pointing out how the report might fall short of its goal, it is directed towards a more reflexive activism.
The interaction of macronutrients and body composition among individuals with chronic spinal cord injury
Authors: Goldsmith Jacob A. , Holman Matthew E. , Puri Puneet , Khalil Refka E. , Ennasr Areej N. , Gorgey Ashraf S. 
Published: June 2022

AbstractChanges in body composition and dietary intake occur following spinal cord injury (SCI). The Geometric Framework for Nutrition (GFN) is a tool that allows the examination of the complex relationships between multiple nutrition factors and health parameters within a single model. This study aimed to utilize the GFN to examine the associations between self-reported macronutrient intakes and body composition in persons with chronic SCI. Forty-eight individuals with chronic SCI were recruited. Participants completed and returned 3- or 5-day self-reported dietary recall sheets. Dietary intake of macronutrients (fats, proteins, and carbohydrates) were analysed. Anthropometric measures (circumferences), dual-energy x-ray absorptiometry (DXA), and magnetic resonance imaging (MRI) were used to assess whlole-body composition. Associations between all circumference measures and carbohydrates were observed. Among MRI measures, only significant associations between subcutaneous adipose tissue and protein x carbohydrate as well as carbohydrates alone were identified. Carbohydrates were negatively associated with several measures of fat mass as measured by DXA. Overall, carbohydrates appear to play an important role in body composition among individuals with SCI. Higher carbohydrate intake was associated with lower fat mass. Additional research is needed to determine how carbohydrate intake influences body composition and cardiometabolic health after SCI.
Old party, new tricks: candidates, parties, and LDP dominance in Japan
Authors: Hamzawi Jordan 
Published: June 2022

AbstractIn 2009, after decades of single party rule under the Liberal Democratic Party (LDP), Japan had its first taste of a real alteration of power. However, just 3 years later, the LDP regained control of government with no significant challenger in sight. Historically, LDP dominance is a common tale, but its resurgence in recent years poses a significant puzzle in Japanese politics. What exactly has contributed to the LDP's return to power? In the years that have passed, the LDP's strength has come from a combination of cash, clientelistic networks, and strong candidates, but recent research has found that Japanese politics has become more programmatic and party-focused. While LDP dominance since its return to power in 2012 can be attributed in part to its candidates, I find that the appeal of the party label has played a large role in securing the LDP's large majorities.
Silence is golden? Silences as strategic narratives in Central Asian states' response to the Ukrainian crisis
Authors: Dadabaev Timur , Sonoda Shigeto 
Published: June 2022

AbstractIn this article, we argue that Central Asian (CA) states' approach to the Ukrainian crisis should be defined as strategic silence. Such foreign policy reflects how CA's ideological and geographic factors and a shared information space, largely dominated by Russian and Russian-language media, facilitate the understanding of historical continuity among Russian and CA leaders. However, we also demonstrate that CA public officials' and general public's uses of strategic silence reflect the complicated reality of CA states. Their leaders and populations are cognizant of both their dependence on educational and labor opportunities in Russia and their necessity for postwar coexistence with Russia, China, and other states that are not sympathetic to the intentions of the European Union/USA in CA. Therefore, strategic silence is an approach for CA states to voice their disagreement with Russia's approach to Ukraine while avoiding being victimized by Russia and its allies for an openly anti-war stance.
Plume‐Slab Interactions Can Shut Off Subduction
Authors: Heilman Erin , Becker Thorsten W. 
Published: June 2022

AbstractMantle plumes are typically considered secondary features of mantle convection, yet their surface effects over Earth's evolution may have been significant. We use 2‐D convection models to show that mantle plumes can in fact cause the termination of a subduction zone. This extreme case of plume‐slab interaction is found when the slab is readily weakened, for example, by damage‐type rheology, and the subducting slab is young. We posit that this mechanism may be relevant, particularly for the early Earth, and a subdued version of these plume‐slab interactions may remain relevant for modern subduction zones. Such core‐mantle boundary–surface interactions may be behind some of the complexity of tomographically imaged mantle structures, for example, in South America. More generally, plume “talk back” to subduction zones may make plate tectonics more episodic.
Representation: raising awareness of opportunities and skill development with undergraduate dental students
Authors: Wakeling Luisa , Blaylock Paul , Harper Matthew , Trevor Miranda , Murphy Holly , Barton Joe , Bateman Heidi 
Published: June 2022

AbstractRepresentatives for dentists are required for many governing committees, local and national, that contribute to many aspects of the profession related to politics, the workplace, education, or community-building. Developing skills as a representative can begin as an undergraduate in student representation systems as part of UK university governance structures. At one UK dental institution, there was a plan to explore the learning and skill development of current student representatives, review the training, identify any areas where there were gaps or where they should be strengthened, and consider whether a new training programme could be developed. Training gaps in the representation process and preference for peer mentoring in training were identified as students acknowledged learning 'on the job' through observation of experienced peers. Current representation training also fell short of highlighting the relevance to their future dental profession. Staff and students co-designed a bespoke programme of training to help students develop their representation skills, as well as align them to the development of professional skills which were determined to be relevant for their future dental career.
Pentraxin 3 regulated by miR-224-5p modulates macrophage reprogramming and exacerbates osteoarthritis associated synovitis by targeting CD32
Authors: Yin Jianbin , Zeng Hua , Fan Kai , Xie Haoyu , Shao Yan , Lu Yuheng , Zhu Jinjian , Yao Zihao , Liu Liangliang , Zhang Hongbo , Luo Bingsheng , Wang Xinjie , Zeng Chun , Bai Xiaochun , Zhang Haiyan , Cai Daozhang 
Published: June 2022

AbstractEmerging evidence has shown an imbalance in M1/M2 macrophage polarization to play an essential role in osteoarthritis (OA) progression. However, the underlying mechanistic basis for this polarization is unknown. RNA sequencing of OA M1-polarized macrophages found highly expressed levels of pentraxin 3 (PTX3), suggesting a role for PTX3 in OA occurrence and development. Herein, PTX3 was found to be increased in the synovium and articular cartilage of OA patients and OA mice. Intra-articular injection of PTX3 aggravated, while PTX3 neutralization reversed synovitis and cartilage degeneration. No metabolic disorder or proteoglycan loss were observed in cartilage explants when treated with PTX3 alone. However, cartilage explants exhibited an OA phenotype when treated with culture supernatants of macrophages stimulated with PTX3, suggesting that PTX3 did not have a direct effect on chondrocytes. Therefore, the OA anti-chondrogenic effects of PTX3 are primarily mediated through macrophages. Mechanistically, PTX3 was upregulated by miR-224-5p deficiency, which activated the p65/NF-κB pathway to promote M1 macrophage polarization by targeting CD32. CD32 was expressed by macrophages, that when stimulated with PTX3, secreted abundant pro-inflammation cytokines that induced severe articular cartilage damage. The paracrine interaction between macrophages and chondrocytes produced a feedback loop that enhanced synovitis and cartilage damage. The findings of this study identified a functional pathway important to OA development. Blockade of this pathway and PTX3 may prevent and treat OA.
A structural and functional subdivision in central orbitofrontal cortex
Authors: Wang Maya Zhe , Hayden Benjamin Y. , Heilbronner Sarah R. 
Published: June 2022

AbstractEconomic choice requires many cognitive subprocesses, including stimulus detection, valuation, motor output, and outcome monitoring; many of these subprocesses are associated with the central orbitofrontal cortex (cOFC). Prior work has largely assumed that the cOFC is a single region with a single function. Here, we challenge that unified view with convergent anatomical and physiological results from rhesus macaques. Anatomically, we show that the cOFC can be subdivided according to its much stronger (medial) or weaker (lateral) bidirectional anatomical connectivity with the posterior cingulate cortex (PCC). We call these subregions cOFCm and cOFCl, respectively. These two subregions have notable functional differences. Specifically, cOFCm shows enhanced functional connectivity with PCC, as indicated by both spike-field coherence and mutual information. The cOFCm-PCC circuit, but not the cOFCl-PCC circuit, shows signatures of relaying choice signals from a non-spatial comparison framework to a spatially framed organization and shows a putative bidirectional mutually excitatory pattern.
Decoupled temperature and pressure hydrothermal synthesis of carbon sub-micron spheres from cellulose
Authors: Yu Shijie , Dong Xinyue , Zhao Peng , Luo Zhicheng , Sun Zhuohua , Yang Xiaoxiao , Li Qinghai , Wang Lei , Zhang Yanguo , Zhou Hui 
Published: June 2022

AbstractThe temperature and pressure of the hydrothermal process occurring in a batch reactor are typically coupled. Herein, we develop a decoupled temperature and pressure hydrothermal system that can heat the cellulose at a constant pressure, thus lowering the degradation temperature of cellulose significantly and enabling the fast production of carbon sub-micron spheres. Carbon sub-micron spheres can be produced without any isothermal time, much faster compared to the conventional hydrothermal process. High-pressure water can help to cleave the hydrogen bonds in cellulose and facilitate dehydration reactions, thus promoting cellulose carbonization at low temperatures. A life cycle assessment based on a conceptual biorefinery design reveals that this technology leads to a substantial reduction in carbon emissions when hydrochar replacing fuel or used for soil amendment. Overall, the decoupled temperature and pressure hydrothermal treatment in this study provides a promising method to produce sustainable carbon materials from cellulose with a carbon-negative effect.
Chain flexibility of medicinal lipids determines their selective partitioning into lipid droplets
Authors: Son So-Hee , Park Gyuri , Lim Junho , Son Chang Yun , Oh Seung Soo , Lee Ju Young 
Published: June 2022

AbstractIn guiding lipid droplets (LDs) to serve as storage vessels that insulate high-value lipophilic compounds in cells, we demonstrate that chain flexibility of lipids determines their selective migration in intracellular LDs. Focusing on commercially important medicinal lipids with biogenetic similarity but structural dissimilarity, we computationally and experimentally validate that LD remodeling should be differentiated between overproduction of structurally flexible squalene and that of rigid zeaxanthin and β-carotene. In molecular dynamics simulations, worm-like flexible squalene is readily deformed to move through intertwined chains of triacylglycerols in the LD core, whereas rod-like rigid zeaxanthin is trapped on the LD surface due to a high free energy barrier in diffusion. By designing yeast cells with either much larger LDs or with a greater number of LDs, we observe that intracellular storage of squalene significantly increases with LD volume expansion, but that of zeaxanthin and β-carotene is enhanced through LD surface broadening; as visually evidenced, the outcomes represent internal penetration of squalene and surface localization of zeaxanthin and β-carotene. Our study shows the computational and experimental validation of selective lipid migration into a phase-separated organelle and reveals LD dynamics and functionalization.
Synthesis of (E)-2-(1H-tetrazole-5-yl)-3-phenylacrylenenitrile derivatives catalyzed by new ZnO nanoparticles embedded in a thermally stable magnetic periodic mesoporous organosilica under green conditions
Authors: Safapoor Sajedeh , Dekamin Mohammad G. , Akbari Arezoo , Naimi-Jamal M. Reza 
Published: June 2022

AbstractZnO nanoparticles embedded in a magnetic isocyanurate-based periodic mesoporous organosilica (Fe3O4@PMO–ICS–ZnO) were prepared through a modified environmentally-benign procedure for the first time and properly characterized by appropriate spectroscopic and analytical methods or techniques used for mesoporous materials. The new thermally stable Fe3O4@PMO–ICS–ZnO nanomaterial with proper active sites and surface area as well as uniform particle size was investigated for the synthesis of medicinally important tetrazole derivatives through cascade condensation and concerted 1,3-cycloaddition reactions as a representative of the Click Chemistry concept. The desired 5-substituted-1H-tetrazole derivatives were smoothly prepared in high to quantitative yields and good purity in EtOH under reflux conditions. Low catalyst loading, short reaction time and the use of green solvents such as EtOH and water instead of carcinogenic DMF as well as easy separation and recyclability of the catalyst for at least five consecutive runs without significant loss of its activity are notable advantages of this new protocol compared to other recent introduced procedures.
Graph convolutional networks fusing motif-structure information
Authors: Wang Bin , Cheng LvHang , Sheng JinFang , Hou ZhengAng , Chang YaoXing 
Published: June 2022

AbstractWith the advent of the wave of big data, the generation of more and more graph data brings great pressure to the traditional deep learning model. The birth of graph neural network fill the gap of deep learning in graph data. At present, graph convolutional networks (GCN) have surpassed traditional methods such as network embedding in node classification. However, The existing graph convolutional networks only consider the edge structure information of first-order neighbors as the bridge of information aggregation in a convolution operation, which undoubtedly loses the higher-order structure information in complex networks. In order to capture more abundant information of the graph topology and mine the higher-order information in complex networks, we put forward our own graph convolutional networks model fusing motif-structure information. By identifying the motif-structure in the network, our model fuses the motif-structure information of nodes to study the aggregation feature weights, which enables nodes to aggregate higher-order network information, thus improving the capability of GCN model. Finally, we conduct node classification experiments in several real networks, and the experimental results show that the GCN model fusing motif-structure information can improve the accuracy of node classification.
Antiprotozoal activity of different Xenorhabdus and Photorhabdus bacterial secondary metabolites and identification of bioactive compounds using the easyPACId approach
Authors: Gulsen Sebnem Hazal , Tileklioglu Evren , Bode Edna , Cimen Harun , Ertabaklar Hatice , Ulug Derya , Ertug Sema , Wenski Sebastian L. , Touray Mustapha , Hazir Canan , Bilecenoglu Duygu Kaya , Yildiz Ibrahim , Bode Helge B. , Hazir Selcuk 
Published: June 2022

AbstractNatural products have been proven to be important starting points for the development of new drugs. Bacteria in the genera Photorhabdus and Xenorhabdus produce antimicrobial compounds as secondary metabolites to compete with other organisms. Our study is the first comprehensive study screening the anti-protozoal activity of supernatants containing secondary metabolites produced by 5 Photorhabdus and 22 Xenorhabdus species against human parasitic protozoa, Acanthamoeba castellanii, Entamoeba histolytica, Trichomonas vaginalis, Leishmania tropica and Trypanosoma cruzi, and the identification of novel bioactive antiprotozoal compounds using the easyPACId approach (easy Promoter Activated Compound Identification) method. Though not in all species, both bacterial genera produce antiprotozoal compounds effective on human pathogenic protozoa. The promoter exchange mutants revealed that antiprotozoal bioactive compounds produced by Xenorhabdus bacteria were fabclavines, xenocoumacins, xenorhabdins and PAX peptides. Among the bacteria assessed, only P. namnaoensis appears to have acquired amoebicidal property which is effective on E. histolytica trophozoites. These discovered antiprotozoal compounds might serve as starting points for the development of alternative and novel pharmaceutical agents against human parasitic protozoa in the future.
Pattern reinstatement and attentional control overlap during episodic long-term memory retrieval
Authors: Sabo Melinda , Schneider Daniel 
Published: June 2022

AbstractEpisodic long-term memory (eLTM) retrieval involves the reinstatement of neural patterns from the encoding phase. However, recent evidence suggests that comparable cortical activity patterns can also be linked to attentional control processes on the level of memory representations. The current investigation assesses these two processes independently based on alpha-beta-band activity in the electroencephalogram (EEG). During encoding, subjects were presented with an object on a certain position on the screen and had to imagine it on a new position. In each trial, either the task-irrelevant presentation position or the task-relevant imagination position was lateralized. In the retrieval phase, subjects first made an old/new judgement based on centrally presented objects and then reported the imagination position. Pattern reinstatement should be reflected in similar lateralized alpha-beta activity during encoding and retrieval. Conversely, the influence of attentional control processes during retrieval would be associated with the suppression of alpha-beta power contralateral to the to-be-reported imagination position and with the increase of activity contralateral to the irrelevant presentation position. Our results support this latter pattern. This shows that an experimental differentiation between selective attention and pattern reinstatement processes is necessary when studying the neural basis of eLTM retrieval.
Viscoelastic bandgap in multilayers of inorganic–organic nanolayer interfaces
Authors: Khadka Rajan , Ramanath Ganpati , Keblinski Pawel 
Published: June 2022

AbstractIncorporating molecular nanolayers (MNLs) at inorganic interfaces offers promise for reaping unusual enhancements in fracture energy, thermal and electrical transport. Here, we reveal that multilayering MNL-bonded inorganic interfaces can result in viscoelastic damping bandgaps. Molecular dynamics simulations of Au/octanedithiol MNL/Au multilayers reveal high-damping-loss frequency bands at 33 ≤ ν ≤ 77 GHz and 278 ≤ ν ≤ 833 GHz separated by a low-loss bandgap 77 ≤ ν ≤ 278 GHz region. The viscoelastic bandgap scales with the Au/MNL interface bonding strength and density, and MNL coverage. These results and the analyses of interfacial vibrations indicate that the viscoelastic bandgap is an interface effect that cannot be explained by weighted averages of bulk responses. These findings prognosticate a variety of possibilities for accessing and tuning novel dynamic mechanical responses in materials systems and devices with significant inorganic–organic interface fractions for many applications, e.g., smart composites and sensors with self-healing/-destructing mechanical responses.
Model architecture can transform catastrophic forgetting into positive transfer
Authors: Ruiz-Garcia Miguel 
Published: June 2022

AbstractThe work of McCloskey and Cohen popularized the concept of catastrophic interference. They used a neural network that tried to learn addition using two groups of examples as two different tasks. In their case, learning the second task rapidly deteriorated the acquired knowledge about the previous one. We hypothesize that this could be a symptom of a fundamental problem: addition is an algorithmic task that should not be learned through pattern recognition. Therefore, other model architectures better suited for this task would avoid catastrophic forgetting. We use a neural network with a different architecture that can be trained to recover the correct algorithm for the addition of binary numbers. This neural network includes conditional clauses that are naturally treated within the back-propagation algorithm. We test it in the setting proposed by McCloskey and Cohen and training on random additions one by one. The neural network not only does not suffer from catastrophic forgetting but it improves its predictive power on unseen pairs of numbers as training progresses. We also show that this is a robust effect, also present when averaging many simulations. This work emphasizes the importance that neural network architecture has for the emergence of catastrophic forgetting and introduces a neural network that is able to learn an algorithm.