bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between parents’ country of birth and smoking risks in South Korean adolescents
Authors: Park Minah , Kim Seung Hoon , Nari Fatima , Jang Bich Na , Park Eun-Cheol 
Published: October 2022

AbstractThis study aimed to determine whether significant associations exist between multicultural families and adolescent smoking risks in South Korea. Data from the Korea Youth Risk Behavior Web-based survey from 2016 to 2020 were analyzed. Participants were classified into four family types (South Korean mother–foreign father, South Korean father–foreign mother, both foreign parents, and both South Korean parents) according to their parents’ country of birth and smoking was assessed using a self-reported questionnaire. A logistic regression analysis was used to examine the significance of the associations. Overall, 194,259 participants (boys: 94,793, girls: 99,466) enrolled in this study. Adolescents whose parents were born overseas were more likely to smoke than native South Korean adolescents (boys: odds ratio [OR] = 2.61, confidence interval [CI] = 1.79–3.81, girls: OR 3.94, CI 2.42–6.43). When the mother’s country of birth was a developing country, there was an increased likelihood of girls smoking, and there was an increased likelihood of smoking among boys when the mother’s country of birth was North Korea. When both parents were born abroad, and the mother’s country of birth was a developing country, the likelihood of smoking risks among their multicultural teenage children increased. Policies and interventions need to be established and implemented to lower the smoking rate among multicultural teenagers.
Straw mulching for enhanced water use efficiency and economic returns from soybean fields in the Loess Plateau China
Authors: Li Feng , Zhang Guohong , Chen Juan , Song Yali , Geng Zhiguang , Li Kefu , Siddique Kadambot H. M. 
Published: October 2022

AbstractWater shortages threaten agricultural sustainability in the semi-arid areas of the Loess Plateau. Judicious mulching management can improve water conservation practices to alleviate this issue while increasing crop productivity. We investigated the effect of straw strip mulching and film mulching on soil water consumption, temperature, growth, grain yield, and economic income of soybean [Glycine max(Linn.) Merr.] from 2017 to 2018 in Qingyang on the semi-arid Loess Plateau in China using four treatments: (a) alternating ridges and furrows with ridges mulched with white polyethylene film (PMP), (b) alternating flat and bare land with only the plat mulched by white polyethylene film (PMF), (c) alternating strips mulched with maize (Zea mays L.) straw (SM), and (d) traditional land planting without mulching (CK). The mulching treatments (PMP, PMF, and SM) increased soil water consumption and soil water use efficiency. The SM, PMF, and PMP treatments had 12.3–12.5, 16.8–22.1, and 23.2–24.2 mm higher soil water consumption (0–120 cm depth) than CK, most of which occurred in the 60–120 cm soil layer. Compared with CK, PMP and PMF significantly increased soil temperature by 1.30–1.31 °C and 0.76–1.00 °C, soybean grain yield by 38.6–39.0 % and 38.8–44.2 %, and water use efficiency (WUE) by 27.7–32.8 % and 30.8–37.5 %, respectively, while SM significantly decreased soil temperature by 0.96–1.15 °C, and increased grain yield by 21.8–25.4 % and WUE by 16.9–21.9 %. PMP and PMF did not significantly change soil water consumption, WUE, or grain yield. The SM treatment increased net income by 501.3–691.7 and 1914.5–2244.9 CNY ha−1 relative to PMP and CK, respectively, but PMF and SM did not significantly differ. Therefore, the SM system could help increase grain yields and economic returns in dryland soybean production, avoiding the adverse effects of the increasingly popular plastic mulching approach.
Enhanced adsorptional-photocatalytic degradation of chloramphenicol by reduced graphene oxide-zinc oxide nanocomposite
Authors: Sodeinde K. O. , Olusanya S. O. , Lawal O. S. , Sriariyanun M. , Adediran A. A. 
Published: October 2022

AbstractImproper discharge of waste dry cell batteries and untreated antibiotics laden effluents to the environment pose serious threat to the sustenance of the ecosystem. In this study, synthesis of reduced graphene oxide-ZnO (rGO-ZnO) nanocomposite was achieved via a bioreduction process using waste dry cell battery rod as graphene oxide (GO) precursor. The nanocomposite was applied in the ultraviolet photocatalytic degradation of chloramphenicol (CAP) at 290 nm in the presence of hydrogen peroxide. RGO-ZnO nanocomposite was characterized by SEM, TEM, XRD, BET and FTIR. TEM image of the nanocomposite revealed a polydispersed, quasi-spherical zinc oxide on a coarse reduced graphene oxide surface. XRD patterns showed sharp, prominent crystalline wurtzite hexagonal phases of ZnO and rGO. BET surface area of the nanocomposite was 722 m2/g with pore size of 2 nm and pore volume of 0.4 cc/g. % photo-removal efficiency increased with increasing irradiation time but diminished at higher pH, temperature and CAP concentration. Photocatalytic adsorption process fitted more accurately into the Freundlich model (R2 = 0.99) indicating a multilayer adsorption mechanism. 92.74% reduction in chemical oxygen demand (COD) level of veterinary effluent was obtained after treatment with the nanocomposite thus affirming its effectiveness in real waste water samples.
Mineralogy, morphology, and reaction kinetics of ureolytic bio-cementation in the presence of seawater ions and varying soil materials
Authors: Burdalski Robert J. , Ribeiro Bruna G. O. , Gomez Michael G. , Gorman-Lewis Drew 
Published: October 2022

AbstractMicrobially-induced calcium carbonate precipitation (MICP) is a bio-cementation process that can improve the engineering properties of granular soils through the precipitation of calcium carbonate (CaCO3) minerals on soil particle surfaces and contacts. The technology has advanced rapidly as an environmentally conscious soil improvement method, however, our understanding of the effect of changes in field-representative environmental conditions on the physical and chemical properties of resulting precipitates has remained limited. An improved understanding of the effect of subsurface geochemical and soil conditions on process reaction kinetics and the morphology and mineralogy of bio-cementation may be critical towards enabling successful field-scale deployment of the technology and improving our understanding of the long-term chemical permanence of bio-cemented soils in different environments. In this study, thirty-five batch experiments were performed to specifically investigate the influence of seawater ions and varying soil materials on the mineralogy, morphology, and reaction kinetics of ureolytic bio-cementation. During experiments, differences in reaction kinetics were quantified to identify conditions inhibiting CaCO3 precipitation and ureolysis. Following experiments, scanning electron microscopy, x-ray diffraction, and chemical composition analyses were employed to quantify differences in mineralogical compositions and material morphology. Ions present in seawater and variations in soil materials were shown to significantly influence ureolytic activity and precipitate mineralogy and morphology, however, calcite remained the predominant CaCO3 polymorph in all experiments with relative percentages exceeding 80% by mass in all precipitates.
iDetect for vulnerability detection in internet of things operating systems using machine learning
Authors: Al-Boghdady Abdullah , El-Ramly Mohammad , Wassif Khaled 
Published: October 2022

AbstractInternet of Things (IoT) 's devices are ubiquitous and operate in a heterogonous environment with potential security breaches. IoT Operating Systems (IoT OSs) are the backbone software for running such devices. If IoT OSs are vulnerable to security breaches, higher-level security measures may not help. This paper aims to use Machine Learning (ML) to create a tool called iDetect for detecting vulnerabilities in C/C++ source code of IoT OSs. The source code for 16 releases of IoT OSs (RIOT, Contiki, FreeRTOS, Amazon FreeRTOS) and the Software Assurance Reference Dataset (SARD) were used to create a labeled dataset of vulnerable and benign code with the reference being the Common Weakness Enumeration (CWE) vulnerabilities present in IoT OSs. Studies showed that only a subset of CWEs is present in the C/C++ source code of low-end IoT OSs.The labeled dataset was used to train three ML models for vulnerability detection: Random Forest (RF), Convolutional Neural Network (CNN), and Recurrent Neural Network (RNN). The three models were used independently and RF; compared to CNN and RNN, gave the highest accuracy during the testing phase for binary and multiclass classification. RF was chosen as iDetect's ML classifier. Further evaluation was done on an unseen dataset of 322 code snippets taken from TinyOS. iDetect achieved a macro-averaged F1 score (mF1) of 98.5% and weighted-average F1 score (wF1) of 98% for multiclass classification, F1 score (F1) of 97.8% for binary classification, and superior results compared to all three Static Analysis Tools (SATs) used to collect the training dataset.
Synthesis and applicability of reduced graphene oxide/porphyrin nanocomposite as photocatalyst for waste water treatment and medical applications
Authors: El-Khawaga Ahmed M. , Tantawy Hesham , Elsayed Mohamed A. , Abd El-Mageed Ahmed I. A. 
Published: October 2022

AbstractThis study presents the synthesis and doping of reduced graphene oxide (rGO) with synthesized porphyrin (5,15-bisdodecyl porphyrin, C12P) nanoparticles to fabricate reduced graphene oxide-porphyrin (rGO-P) nanocomposite as well as demonstrates their outstanding removal activity of azo dye and antimicrobial potential. The synthesized porphyrin, rGO, and rGO-P nanocomposites were characterised using SEM, HRTEM, Raman spectroscopy, XRD, 1H-NMR, mass spectrometry, and UV–Visible spectroscopy. The ability of the synthesized rGO-P nanocomposite was then investigated (as catalyst and/or adsorbent) to impact its removal efficacy against Congo red (CR) as a well-known toxic, mutagenic and carcinogenic synthetic dye. The findings indicated that 0.01 g of rGO-P nanocomposite achieved 78.0% removal of CR at pH 3.0. Besides, the removal efficacy was evaluated while studying many aspects i.e. pH, CR initial concentration, and rGO-P nanocomposite amount. Moreover, the minimum inhibitory concentration (MIC) and zone of inhibition (ZOI) of antimicrobial activity against pathogenic bacteria and yeast were evaluated. The antimicrobial results showed that rGO-P nanocomposite revealed the greatest antimicrobial activity against Candida albicans, Enterococcus faecalis, and Staphylococcus aureus with ZOI values of 24.3, 21.8, and 22.1 mm, respectively. Consequently, it demonstrates the substantial potential of rGO-P nanocomposite in the effective removal of pollutant dyes as well as significant antibacterial and antifungal properties.
Ultrasensitive colorimetric detection of fluoride and arsenate in water and mammalian cells using recyclable metal oxacalixarene probe: a lateral flow assay
Authors: Dey Shuvankar , Kumar Anshu , Mondal Pradip Kumar , Chopra Deepak , Roy Rupam , Jindani Sana , Ganguly Bishwajit , Mayya Chaithra , Bhatia Dhiraj , Jain Vinod K. 
Published: October 2022

AbstractGlobally 3 billion people are consuming water with moderately high concentrations of fluoride and arsenic. The development of a simple point of care (PoC) device or home device for the detection of fluoride/arsenic ensures safety before consuming water. Till date, lateral flow assay (LFA) based PoC devices can detect nucleic acids, viruses and diseases. An aluminium complex of rhodamine B functionalized oxacalix[4]arene (L) was designed to execute the LFA-based PoC device. Initially, Al3+ and Fe3+ ions were involved in complexation with the rhodamine B functionalized oxacalix[4]arene (L), resulting C1 (L-Al3+) and C2 (L-Fe3+) complexes respectively. The receptor L, as well as the probes (C1, C2), were characterized thoroughly using mass spectroscopy, FTIR, NMR, and EA. C1 and C2 were further utilized as recyclable probes for the detection of aqueous fluoride (21 ppb) and arsenate (1.92 ppb) respectively. The computational calculation indicates that upon complexation, the spirolactam ring opening at the rhodamine B site leads to optoelectronic changes. The consistency of LFA-based portable sensing device has been tested with water samples, synthetic fluoride standards and dental care products like toothpaste and mouthwash with concentrations ≥ 3 ppm. Moreover, fixed cell imaging experiments were performed to ascertain the in-vitro sensing phenomena.
Stannous colloid mixed with indocyanine green as a tracer for sentinel lymph node navigation surgery
Authors: Zhang Yiting , Uehara Tomoya , Toyota Taro , Endo Ryusuke , Matsubara Hisahiro , Hayashi Hideki 
Published: October 2022

AbstractThe combined use of a vital dye and radioactive colloid reportedly performs better in detecting sentinel lymph nodes (SLNs) for cancers than the use of either of them alone. However, especially for gastric cancer, two endoscopic procedures are required to administer these two tracers, which burdens the patients and practitioners. Here we propose the use of stannous colloid (SnC) mixed with indocyanine green (ICG) as a new mixed tracer (SnC–ICG); its characteristics were investigated in vivo and in vitro to estimate its usefulness for SLN navigation. The tracers were administered to rats and the accumulation of radioactivity and/or near-infrared fluorescence were evaluated in the regional lymph nodes (LNs) using single positron emission computed tomography and near-infrared fluorescence imaging, respectively. SnC–ICG showed significantly better clearance from the injection site and better migration to primary LNs than the single administration of SnC or ICG aqueous solution. SnC–ICG demonstrated a wide particle size variability, stabilized to 1200-nm upon the addition of albumin in vitro; These properties could contribute to its behavior in vivo. The use of SnC–ICG could contribute better performance to detect SLNs for gastric cancer with less burden on both patients and medical practitioners.
Exploring the association between cognitive decline and all-cause mortality with blood pressure as a potential modifier in oldest old individuals
Authors: Duan Jun , Sam Napoleon Bellua , Wang Shi-Jia , Liu Yan 
Published: October 2022

AbstractFew studies have systematically explored the association between cognitive decline and all-cause mortality among oldest old individuals (above 80 years old), and there is limited evidence of blood pressure (BP) as a potential effect modifier. Therefore, this study included 14,891 oldest old individuals (mean age: 90.3 ± 7.5 years); 10,904 deaths and 34,486 person-years were observed. Cognitive scores were calculated using the Chinese version of the Mini-Mental State Examination (MMSE). Cognitive decline was stratified into ten categories (C0–C9). Continuous cognitive scores were used to assess the interactions of modifiers of the cognitive decline and all-cause mortality association and potentially modifiable factors. Potential effect modifiers were explored by age, sex, BP status and hypertension. Cox proportional hazards models were used to evaluate the relationship between cognitive decline and all-cause mortality after adjustments for demographic characteristics, socioeconomic status, lifestyle factors, leisure activities and health conditions. Participants who progressed to severe cognitive impairment from high normal cognitive function (C3), low normal cognitive function (C6), or mild cognitive impairment (C8) had 55%, 56%, and 63% higher mortality risks, respectively, than those who maintained high normal cognitive function (C0). The multivariate-adjusted model indicated that oldest old individuals with a decrease of more than one point in the MMSE score per year had an approximately 4% all-cause mortality risk. The relationship between cognitive decline and mortality was statistically influenced by sex (P = 0.013), high BP in nonagenarians (P = 0.003), and hypertension (P = 0.004) but not by age (P = 0.277). Our findings suggest that periodic screening for cognitive decline and strengthening BP management may be necessary for public health.
The purine metabolite inosine monophosphate accelerates myelopoiesis and acute pancreatitis progression
Authors: Luo Xiao-Min , Lam Sin Man , Dong Yuan , Ma Xiao-Juan , Yan Cen , Zhang Yue-Jie , Cao Yu , Su Li , Lu Guotao , Yang Jin-Kui , Shui Guanghou , Feng Ying-Mei 
Published: October 2022

AbstractHyperglycemia-induced myelopoiesis and atherosclerotic progression occur in mice with type I diabetes. However, less is known about the effects of metabolites on myelopoesis in type 2 diabetes. Here, we use fluorescence-activated cell sorting to analyze the proliferation of granulocyte/monocyte progenitors (GMP) in db/db mice. Using targeted metabolomics, we identify an increase in inosine monophosphate (IMP) in GMP cells of 24-week-old mice. We show that IMP treatment stimulates cKit expression, ribosomal S6 activation, GMP proliferation, and Gr-1+ granulocyte production in vitro. IMP activates pAkt in non-GMP cells. In vivo, using an established murine acute pancreatitis (AP) model, administration of IMP-treated bone marrow cells enhances the severity of AP. This effect is abolished in the presence of a pAkt inhibitor. Targeted metabolomics show that plasma levels of guanosine monophosphate are significantly higher in diabetic patients with AP. These findings provid a potential therapeutic target for the control of vascular complications in diabetes.
Non-equilibrium dynamics of bacterial colonies—growth, active fluctuations, segregation, adhesion, and invasion
Authors: Zhou Kai , Hennes Marc , Maier Berenike , Gompper Gerhard , Sabass Benedikt 
Published: October 2022

AbstractColonies of bacteria endowed with a pili-based self-propulsion machinery are ideal models for investigating the structure and dynamics of active many-particle systems. We study Neisseria gonorrhoeae colonies with a molecular-dynamics-based approach. A generic, adaptable simulation method for particle systems with fluctuating bond-like interactions is devised. The simulations are employed to investigate growth of bacterial colonies and the dependence of the colony structure on cell-cell interactions. In colonies, pilus retraction enhances local ordering. For colonies consisting of different types of cells, the simulations show a segregation depending on the pili-mediated interactions among different cells. These results agree with experimental observations. Next, we quantify the power-spectral density of colony-shape fluctuations in silico. Simulations predict a strong violation of the equilibrium fluctuation-response relation. Furthermore, we show that active force generation enables colonies to spread on surfaces and to invade narrow channels. The methodology can serve as a foundation for future studies of active many-particle systems at boundaries with complex shape.
Effects of limiting digital screen use on well-being, mood, and biomarkers of stress in adults
Authors: Pedersen Jesper , Rasmussen Martin Gillies Banke , Sørensen Sarah Overgaard , Mortensen Sofie Rath , Olesen Line Grønholt , Brage Søren , Kristensen Peter Lund , Puterman Eli , Grøntved Anders 
Published: October 2022

AbstractStudies have linked higher digital screen use with poorer mental health. However, there is limited experimental evidence to suggest a causal relationship. In this trial, we aimed to investigate the effects of limiting recreational digital screen use on mental well-being, mood, and biomarkers of stress in healthy young and middle-aged adults. We randomly allocated 89 families (including 164 adults) to participate in an extensive screen media reduction intervention or control. Participants in the intervention group were instructed to decrease their recreational screen use to less than 3 hours/week/person. Intervention compliance was assessed using applications and tv-monitors. Overall subjective mental well-being and mood, and collected daily biomarkers of stress (salivary cortisol and cortisone) was assessed at baseline and 2-week follow-up. Reducing recreational digital screen use resulted in significantly improved self-reported well-being and mood in adults allocated to the intervention compared to control. We observed no intervention effects for biomarkers of stress. (ClinicalTrials.gov: NCT04098913, 23/09/2019).
An Evaluation of the P300 Brain–Computer Interface, EyeLink Board, and Eye-Tracking Camera as Augmentative and Alternative Communication Devices
Authors: Elliott Claire , Sutherland Dean , Gerhard Daniel , Theys Catherine 
Published: October 2022

Purpose:Augmentative and alternative communication (AAC) systems are important to support communication for individuals with complex communication needs. A recent addition to AAC system options is the brain–computer interface (BCI). This study aimed to compare the clinical application of the P300 speller BCI with two more common AAC systems, the EyeLink board, and an eye-tracking camera.Method:Ten participants without communication impairment (18–35 years of age) used each of the three AAC systems to spell three-letter words in one session. Accuracy and speed of letter selection were measured, and questionnaires were administered to evaluate usability, cognitive workload, and user preferences.Results:The results showed that the BCI was significantly less accurate, slower, and with lower usability and higher cognitive workload compared to the eye-tracking camera and EyeLink board. Participants rated the eye-tracking camera as the most favorable AAC system on all measures.Conclusions:The results demonstrated that while the P300 speller BCI was usable by most participants, it did not function as well as the eye-tracking camera and EyeLink board. The clinical use of the BCI is, therefore, currently difficult to justify for most individuals, particularly when considering the substantial cost and setup resourcing needed.Supplemental Material:https://doi.org/10.23641/asha.21291384
Un appel à volontaires en contexte de pandémie de Covid-19 en école de médecine. Rite de passage pour des étudiants de médecine de deuxième année
Authors: Pâme Patricia , Cazemajou Anne , Josset Jean-Marc 
Published: October 2022

Contexte et problématique : Pendant la première vague de la pandémie de la Covid-19, des étudiants de médecine de deuxième année ont été sollicités pour aider des services de santé débordés. Bien que peu ou pas formés à ce stade, la plupart se sont engagés après un processus de décision. Objectif : Éclairer les processus implicites sous-jacents à la décision des étudiants de répondre à l’appel à volontariat. Méthodes : Six entrevues répondant aux principes de l’entretien d’explicitation ont été conduites auprès d’un échantillon de disponibilité d’étudiants de deuxième année d’une faculté de médecine française. Les verbatim des entrevues ont été analysés en lien avec le modèle conceptuel élaboré par l’ethnologue et folkloriste van Gennep concernant les « rites de passages ». Résultats : L’analyse effectuée révèle que l’appel à volontariat a suscité chez les étudiants des réactions en lien avec la construction de leur identité de (futur) médecin. À l’instar de ce qui est observé dans les processus en jeu dans les rites de passage, elle souligne la coupure avec le milieu antérieur (familial, amical), l’importance des modèles-guides et de la confraternité qui sont déjà à l’œuvre. Bien qu’il s’agisse d’une étude exploratoire, basée sur un évènement particulier et un échantillon réduit, nos observations rejoignent celles d’autres travaux plus significatifs mais portant sur une phase plus avancée de la formation des futurs médecins.