bluuebunny/crossref_metadata_2025_split huggingface dataset:
SIMULATION OF AIR FILTERING IN MOBILE PREMISES UNDER CONDITIONS OF THE ENEMY’S FIRE FOR EFFECT
Authors: Borta R. , Kotsyuruba V. , Vetoshkin A. , Yermolenko O. 
Published: May 2022

Modern military equipment has a filter ventilation system, employment of which plays a vital role in survival of personnel when equipment enters the cloud of contaminated air with toxic and chemical warfare agents, bacteriological aerosols and hazardous chemicals used in the national economy.
The filter ventilation system cleans the air from chemical, biological, radiological agents and supplies it to the objects of collective protection in order to ventilate the premises, provide air to personnel, as well as create excess pressure that prevents external contaminated air due to leaks in enclosing structures objects.
The article presents an improved mathematical model of the functioning of filter ventilation systems in mobile premises under conditions of enemy fire. In contrast to the existing ones, it takes into account the dynamics of changes in the total area of leaks of mobile premises depending on the intensity of fire for effect and the time of their stay under fire. The results of the study of the dependence of the dynamics of changes in the total area of leaks of mobile premises depending on the intensity of the fire and the time spent under fire are highlighted.
Thus the offered model allows to receive values of indicators of safe stay of personnel in mobile premises and necessary productivity of filter ventilating installations under conditions of chemical, biological, radiological and nuclear incident.
As a direction of further research, modeling of personnel losses depending on the intensity of fire for effect and concentration of toxic substances in the air using simulation models can be used.
Protective effect of dexmedetomidine pre treatment against myocardial ischemia reperfusion injury in rats
Authors: Sha Qin , Jiang Hui 
Published: May 2022

Purpose: To determine the protective effect of dexmedetomidine pre-treatment against myocardial ischemia-reperfusion injury (MRI), and the involvement of ER stress and protein kinase R-like ER enzyme (PERK) signaling pathway in the process.
Methods: Sixty male Sprague-Dawley (SD) rats were assigned to three groups: sham, model (ischemia-reperfusion), and dexmedetomidine pre-treatment groups. Myocardial infarction area was measured using 2,3,5-triphenyl tetrazolium chloride (TTC) method. Changes in heart structure were examined using H & E, while myocardial cell apoptosis was determined with TUNEL assay. The protein expression levels of CHOP, glucose regulatory protein 78, ATF4, eukaryotic translation initiation factor 2-α (elf2-α), and PERK were assayed with Western blotting.
Results: RPP, myocardial infarction area, myocardial cell apoptosis rate, and the expression levels of CHOP, GRP78, ATF4, elf2-α, and PERK were significantly raised, relative to sham. The structure of myocardial cells in sham-operated rats was intact and orderly. In contrast, the arrangement of myocardial cells in the model group was disordered, and the myofibrils were broken or wavy. However, the arrangement of myocardial cells in the dexmedetomidine group was significantly improved, when compared with the model group.
Conclusion: Pretreatment with dexmedetomidine may exert a protective effect against MRI through suppression of ER stress and PERK signaling pathway. Further preclinical studies would be required to validate these findings.
STRATEGI PENGEMBANGAN USAHA MELALUI BISNIS MODEL CANVAS KERAJINAN PONDOK PESANTREN AL-FALAH PLOSO,MOJO,KEDIRI.
Authors: Nur Alifiyah Nur Alifiyah 
Published: May 2022

Abstrak :
Kegiatan Wirausaha yang dilakukan di Pondok Pesantren Al-Falah Ploso Mojo Kediri adalah salah satu program kemandirian ekonomi pesantren Bank Indonesia yang diberikan untuk meningkatkan kemajuan program kemandirian ekonomi pesantren dari segi finansial dan menciptakan minat berwirausaha bagi pemuda. Selain itu, Penelitian ini bertujuan untuk meningkatkan produktifitas usaha agar semakin berkembang dan mampu bersaing di pasar. Untuk mengembangkan usaha kerajinan tenun, manager unit usaha Pondok Pesantren Al-Falah Ploso Mojo Kediri perlu memperbaiki strategi usaha dengan tujuan meningkatkankan penjualan dan pendaptan. Upaya peningkatan kualitas strategi usaha dilakukan dengan menganalisis sembilan elemen kunci Bisnis Model Canvas dan dianalisis mendalam menggunakan analisis SWOT untuk uji kekuatan (Strength), kelemahan (Weakness), ancaman (Threats ) dan kesempatan (Opportunity). Penelitian ini merupakan penelitian kualitataif yang disajikan secara deskriptif dan menghasilkan empat implikasi menejerial yang perlu perbaikan strategi usaha.
Kata Kunci : Bisnis Model Canvas, Analisis SWOT, Kemandirian Ekonomi Pesantren, Strategi Manajemen, Strategi Pengembangan Bisnis
Effect of altitude differences on seed germination and seedling growth in Rhododendron luteum Sweet
Authors: Pulatkan Müberra , Kamber Asena Şule 
Published: May 2022

The aim of this study is to encourage the use of Rhododendron luteum Sweet, distributed in high altitudes in its natural habitat, in planting designs and landscape architecture and to cultivate these plants by seed propagation. In this context, the effects of different altitudes on R. luteum germination and post-germination seedling growth were investigated. The germination success of R. luteum seeds collected at 3 different altitudes, 1,586 m, 1,760 m and 2,100 m a.s.l., was investigated under greenhouse conditions at a temperature of 25 ± 2 °C and humidity of 70 ± 2% and in soil, peat, soil + peat (5:5), peat + sand (7:3), soil + sand (7:3) and soil + peat + sand (4:4:2) propagation media. The post-germination seedling height, root length, and the number of leaves of the seedlings were determined. Different altitudes had significant effects (P < 0.05) on height, root length, and the number of leaves of the seedlings. The highest germination percentage was 76.69% with the seeds collected from 2,100 m. Furthermore, seedlings that grew from these seeds possessed the best seedling growth with a greater height, longer roots, and a greater number of leaves. Keywords: landscape architecture, Rhododendron luteum, seed propagation, variation
Historical review, analysis and prospects for the development of tram traffic in St. Petersburg
Authors: Vadopolas J. R. , Sugorovsky A. V. 
Published: May 2022

St. Petersburg is a large, populous city. It needs a well-developed transport infrastructure. One of the main advantages of the tram is its uninterrupted operation in almost all-weather conditions.Currently, the park of public transport in St. Petersburg is being updated, priority is given to environmentally friendly transport, the use of electric transport, gas motor fuel.The question of the implementation of projects that would improve the ecological situation in the city is relevant. The tram has the largest carrying and throughput capacity among urban land transport and a signifi cant service life. It is an environmentally friendly type of ground urban passenger transport while ensuring a high level of passenger safety. The development of tram traffi c is analyzed.The advantages of using this type of ground urban passenger transport are considered. The tram market in Russia has been studied and two options for updating the rolling stock have been proposed.In order to study public opinion, a survey of more than a hundred students of the Emperor Alexander I St. Petersburg State Transport University was carried out.A survey was conducted among residents of diff erent districts of the city, it was proposed to change some routes and add new routes within the existing tram lines.The necessity of updating the rolling stock, contact network and traction substations is substantiated; isolation of tram lines; railroad upgrades; reforming the route network; creation of convenient infrastructure at bus stops. Options for implementing the development of tram traffi c are proposed.
PENGEMBANGAN E-LEARNING BERORIENTASI PEMBELAJARAN INKUIRI BERBASIS PENDIDIKAN KARAKTER PADA MATA KULIAH DESAIN PEMBELAJARAN
Authors: Triwahyuni Eges , Pradana Pascalian Hadi 
Published: May 2022

Penelitian ini bertujuan untuk: 1) mengetahui rancang bangun e-learning berorientasi pembelajaran inkuiri berbasis pendidikan karakter pada mata kuliah desain pembelajaran, 2) mengetahui kelayakan e-learning berorientasi pembelajaran inkuiri berbasis pendidikan karakter pada mata kuliah desain pembelajaran, 3)

5

mengetahui keefektifan e-learning berorientasi pembelajaran inkuiri berbasis pendidikan karakter pada mata kuliah desain pembelajaran. Penelitian ini merupakan penelitian dan pengembangan (research and development). Model pengembangan yang digunakan adalah model Borg & Gall. Subjek coba pada uji kelayakan adalah mahasiswa semester 3 tahun akademik 2020-2021 sebanyak 35 orang mahasiswa sedangkan subjek coba pada uji efektifitas adalah mahasiswa Jurusan Teknologi Pembelajaran Universitas PGRI Argopuro Jember semester 2 tahun akademik 2021-2022. Instrumen yang digunakan untuk mengumpulkan data pada penelitian ini berupa angket, tes hasil belajar, dan lembar pengamatan perilaku berkarakter. Analisis data menggunakan analisis statistik deskriptif dan statistik inferensial (uji-t). Hasil penelitian menunjukkan: 1) rancang bangun pengembangan e-learning meliputi langkah analisis kebutuhan, pengembangan desain pembelajaran, membangun course e-learning, evaluasi formatif, dan evaluasi sumatif, 2) hasil validasi ahli materi pada aspek pembelajaran memperoleh skor 4,36 (sangat baik) dan pada aspek isi/materi memperoleh skor 4,8 (baik), hasil validasi ahli media pada aspek tampilan memperoleh skor 4,28 (sangat baik) dan pada aspek pemrograman memperoleh skor 4,44 (baik), hasil uji coba lapangan pada aspek pembelajaran memperoleh skor 4,61 (sangat baik) dan pada aspek isi/materi memperoleh skor 4,55(sangat baik), pada aspek tampilan memperoleh skor 4,56 (sangat baik) dan pada aspek pemrograman memperoleh skor 4,67 (sangat baik), 3 hasil uji efektifitas menunjukkan sig 0.000 atau kurang dari 0.05, maka dapat disimpulkan ada perbedaan hasil belajar yang signifikan sebelum dan sesudah menggunakan e-learning Edutech Smart pada mahasiswa semester 2 tahun akademik 2021-2022 mata kuliah desain pembelajaran. Dari hasil tersebut dapat dikatakan bahwa media pembelajaran yang dikembangkan efektif dan dapat meningkatkan kualitas pembelajaran pada mata kuliah desain pembelajaran.
Overall survival analysis of > 65-year-old patients with breast cancer based on their molecular, clinicopathological and laboratory factors
Authors: Huszno Joanna , Kolosza Zofia , Mrochem -Kwarciak Jolanta , Grzybowska Ewa 
Published: May 2022

IntroductionThe objective of the present study was to characterize > 65-year-old patients with breast cancer according to clinicopathological, molecular and laboratory factors.Material and methodsA total of 723 breast cancer patients, who had been diagnosed and treated during 2005–2019, were retrospectively reviewed. Patients > 65 years of age (92 patients) were compared with < 50-year-old women (306 patients). We analyzed 398 women from 723 patients.ResultsOverall survival analysis was conducted for both groups, separately and combined. Patients with BC aged > 65 years were characterized by G1-2, higher lymphocyte values, lower platelet (PLT) counts and lower NLR or PLR values than patients <50 years of age.ConclusionsAge > 65 years is a negative prognostic factor independent of other factors.
School Problems among Left-Behind Children of Labor Migrant Parents: a study in Vietnam
Authors: Nguyen Luot , Nguyen Nhung , Truong Ha , Giang Mai 
Published: May 2022

BackgroundMany studies have shown the effects of parental migration on the psychological and daily life of left-behind children (LBC) of labor migrant parents, but the results on school-related problems of LBC remain inconsistent. Additionally, there is a dearth of research on the factors affecting school problems among LBC, especially in the socio-cultural context of Vietnam. The purpose of this study was to confirm the school problems encountered by LBC in comparison with non-left-behind children (non-LBC). The study also aimed to examine variables of bonding of caregivers with children and resilience of children affecting school problems of LBC.Participants and procedureThe convenient sampling approach was used in the study. The study sample included 792 Vietnamese school students (M¬age = 12.65, SD = 1.60), with 439 children of labor migrant parents and a control group of 353 children of non-migrant parents. The School Problem Questionnaire, Parental Bonding Instrument and the Resilience Scale were employed in this study.ResultsThere was no difference in school problems between the LBC and non-LBC groups. Resilience by goal planning (RGP), resilience by affect control (RAC), and resilience by family support (RFS) are identified as protective variables for children to overcome difficulties encountered in schools, with regression coefficients of -.21, -.33 and -.20, respectively. Meanwhile, bonding of caregivers with children by control (BCCo), resilience by positive thinking (RPT) are considered as factors that increase school problems among LBC with the same regression coefficient of .12.ConclusionsActivities to support LBC should pay attention to improving resilience, namely affect control, goal planning, and promoting the role of caregivers for LBC.
Phytochemical analysis and cytotoxicity of Clinacanthus nutans on human gingival fibroblast cell line
Authors: Ab Alim A’attiyyah , Wan Ghazali Wan Afiqah Syahirah , Mohd Ali Nor Azah , Ponnuraj Kannan Thirumulu , Mohamad Suharni , Azlina Ahmad 
Published: May 2022

Introduction and Aim: Clinacanthus nutans (C. nutans) possesses antimicrobial, anticancer, and anti-inflammatory activities. The present study aimed to carry out phytochemical analyses of aqueous and ethanolic extracts of C. nutans leaves and also its cytotoxic potential on human gingival fibroblast cell line HGF-1.

Materials and Methods: Phytochemical analyses was conducted using Gas Chromatography Mass Spectrometry (GCMS). Cytotoxicity testing was carried out by treating the HGF-1 with different concentrations (50,100, 200, 400, 800, 1600, 3200, 6400 µg/ml) of both the aqueous and ethanolic extracts of C. nutans leaves using MTT assay. The control comprised only the cell suspension and culture medium.

Results: Phytochemical study revealed 53 compounds. Furfural, 2-furanmethanol, butyrolactone, phenol, benzeneacetaldehyde, 4H-Pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl-, vitamin E, campesterol, stigmasterol,.gamma.-Sitosterol and lupeol were the compounds identified in both extracts. Both the extracts did not exhibit any cytotoxicity on HGF-1 based on MTT assay with IC50 values of 1099 µg/ml (ethanol extract) and 2627 µg/ml (aqueous extract).

Conclusion: This study showed that ethanol and aqueous extracts of C. nutans leaves contained varied phytochemical compounds and were non-cytotoxic on human gingival fibroblast cell line under the present test conditions.
Influence of duration of menopause on bone turnover markers in post-menopausal women
Authors: Rai Tirthal , Rai Mayur , DSa Janice , Rai Srinidhi , Hegde Rishabh 
Published: May 2022

Introduction and Aim: Osteoporosis is common among women following 10 years of cessation of menstruation, due to bone loss accelerated by menopause. The study was done to evaluate the effect of duration of menopause on bone turnover markers (BTMs).

Materials and Methods: The study involved 100 postmenopausal women; 50 osteoporotic and 50 non-osteoporotic. Comparison and correlation of serum calcium, phosphorus, alkaline phosphatase (ALP), serum osteocalcin (sOC) and urinary hydroxyproline (uHP) were done based on duration of menopause. Comparison of biochemical parameters was done using Independent t-test and ANOVA test for two groups and more than two groups respectively. Correlation was done using Pearson’s correlation test. Statistical significance was considered at p<0.05.

Results: The sOC significantly declined and uHP levels increased between quartiles of duration of menopause among study participants. (p<0.001). However, in those without fractures, sOC and uHP were higher in those with <7 years since menopause (YSM) and then plateaued after 8 YSM. The percentage of osteoporotic women having >15 YSM was 82%. Duration of menopause correlated better with sOC (r=-0.633) than uHP (r=0.575) (p<0.001).

Conclusion: Osteoporotic fractures were higher in more than 15 YSM. There was no difference in both sOC and uHP in those with fractures, proving non-significance of screening these markers once the fractures have occurred. As sOC correlates better with duration of menopause, monitoring of sOC in early years of menopause is required to prevent osteoporotic fractures and associated burden through prophylactic treatment.
Folklore claims of medicinal plants against sprain from the Western Ghats region of Dakshina Kannada district, Karnataka state, India
Authors: A. Yogeesha , G. Krishnakumar 
Published: May 2022

Introduction and Aim: Plants form the primary source of medicinesboth in traditional and modern methods of treatment. People residing at remote and rural regions still depend on traditional herbal medicine for their primary health care needs. This study aimed to document ethnomedicinal plants used in the treatment of sprain in the Western Ghats region of Dakshina Kannada district, Karnataka state, India.

Materials and Methods: An ethnobotanical study was carried out in Western Ghatsregion of Dakshina Kannada district, Karnataka during 2018-2021 to document the medicinal plants used by traditional practitioners to treat sprain. Data was collected using a semi structured questionnaire and open-ended interviews with herbal healers. Data was analyzed using simple statistical methods and few quantitative parameters.

Results: A total of 40 plant species of belonging to 30 families have been documented. Some significant recorded plant species are Aloe vera, Litsea glutinosa, Cissus quadrangularis, Abrus pulchellus, Antidesma acidum, Holarrhena pubescens, Litsea wightiana and Ziziphus rugosa. Younger generations are ignoring the uses and cultural importance given to such ethno- medicinal practices. This knowledge is based on oral tradition often passed on to the next generation.

Conclusion: Practitioners of this region do not have any written documents pertaining to their precious knowledge. Hence there is an urgent requirement to document and preserve the traditional knowledge inherited by tribes and ethnic communities before it is completely lost.
Efficacy of enhanced external counter pulsation in improving six minutes’ walk test in heart failure patients
Authors: Subramanian Ramasamy , Shiek Ahmed , Meyyappan Chokkalingam 
Published: May 2022

Introduction and Aim: Enhanced External Counterpulsation (EECP) is an outpatient treatment to improve myocardial perfusion in chronic stable angina patients. We studied the clinical response of heart failure patients' improvement in the functional class and exercise tolerance with EECP.

Materials and Methods: We prospectively evaluated twenty-six patients, who had completed a course of EECP with pre and post six minutes’ walk test, functional ability assessed by the New York heart association (NYHA) classification, renal parameters, lipid profile, and diastole to systole(d/s) ratio in terms of Peak amplitude (P) and Area (A) under the curve value.

Results: The study group's mean age is of 56 years. The mean left ventricular ejection fraction (LVEF) is 31.44± 5.5%. Patients' demography includes 81% were male, 30% with hypertension (HT),50% with diabetes mellitus (DM), 30%chronic smokers, 61% of them had triple vessel disease (TVD). All the patients improved by a minimum of one NYHA class improvement, Serum urea reduced from 34.37 ± 20.28 to 27.24 ± 18.73 mg/dL (P = 0.002), C-Reactive protein (CRP) reduced from 4.6± 8.0 to 3.76 ± 5.1 mg/dL (P = 0.62). In the measured lipid panel test, only low-density lipoprotein (LDL) reduction from 94.41 ± 38.66 to 80.51 ± 35.09 mg/dL was statistically significant (P =0.03). The six-minute walk test, post-EECP, improved significantly from 340.14 ± 68.5 to 385.5 ± 73.9 meters (P =0.0004). The LVEF increased from 31.44 ± 5.5 to 38.38 ± 8.69 % (P=0.001).

Conclusion: EECP treatment significantly improves shortness of breath, six minutes walking distance, and ejection fraction in heart failure patients. The treatment significantly reduces serum urea and LDL level. These positive changes may be due to a sudden increase in cardiac output and hyperdynamic circulation during the treatment.
Umbilical cord serum lipid profile of healthy neonates- A single center study from rural Tamil Nadu, India
Authors: A.G. Narayanaswamy , K. Meenakshi , S. Porchelvan , J. Vinoth Kumar , S. Bavya , E. S. SharanyaShre 
Published: May 2022

Introduction and Aim: Umbilical cord lipid profile of neonates might help facilitate the assessment of risk of developing atherosclerotic disorders later in life. This study prospectively measures the cord blood lipid profile of healthy newborn at birth in medical college hospital in rural Tamil Nadu.
Material sand Methods: Consecutive full-term newborns (n=105) were enrolled for this study. Umbilical cord blood sample was collected from placental end of the cord immediately after delivery of placenta of each baby and sent to the lab for lipid profile estimation.
Results: In the newborns born to non-diabetic mothers, the mean cord blood total serum cholesterol (TC) was 73.31mg %, triglyceride (TGL) was 51.50mg %, high-density lipoproteins (HDL) 24.62 mg % and low-density lipoproteins (LDL) 51.73 mg %. Amongst newborns born to diabetic mothers, the mean TC was 113 mg % (P = 0.001), TGL 98.08mg% (P = 0.045) HDL 28.75 mg% (P = 0.130) LDL 73.48mg% (P = 0.007). Umbilical cord blood lipid profile did not show any significant sex-dependent difference. There was no statistical difference in lipid values between appropriate for gestational age (AGA)and small for gestational age (SGA). Birth weight had a negative correlation to cord blood serum TC and TGL values and showed no correlation to HDL and LDL values. Other parameters including head circumference, length of newborn at birth also showed no correlation to lipid profile. Total cholesterol, TGL and LDL were significantly elevated in newborns born to diabetic mothers. There was no statistical difference in cord blood lipid profile of babies born to mothers who were hypertensive.
Conclusion: Infants born to diabetic mothers tend to have significantly elevated lipid values at birth and must be followed regularly later in life to diagnose and treat dyslipidemia and diabetes, to prevent onset of premature atherosclerotic coronary artery disease in this population.