bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Surface Fluxes on Ventilation Pathways and the Intensification of Hurricane Michael (2018)
Authors: Alland Joshua J. , Davis Christopher A. 
Published: January 2022

Abstract
This study investigates the effects of surface fluxes on ventilation pathways and the development of Hurricane Michael (2018), and is a real-case comparison to previous idealized modeling studies that investigate ventilation. Two modeling experiments are conducted by altering surface exchange coefficients to achieve a strong and weak experiment. Ventilation pathways are evaluated to understand how the vortex responds to dry-air infiltration. Pathways for dry-air infiltration are split into downdraft and radial ventilation. Results show that downdraft ventilation at low levels is maximized left of shear, exists between the surface and a height of 3 km, and is associated with rainband activity. Trajectories from downdraft ventilation demonstrate slower thermodynamic recovery for the weaker experiment. The slower recovery contributes to the initial intensity bifurcation between experiments. Radial ventilation has two pathways. At low levels, it is coupled with downdraft ventilation. Aloft, between heights of 5 and 10 km, it is maximized upshear and associated with storm-relative flow. This pathway is similar for each experiment initially, suggesting that the initial bifurcation of intensity is not a consequence of radial ventilation aloft. Trajectories from radial ventilation during a later time period show the destructive impact of lower-θe air in the near environment on convection upshear and right of shear for the weaker experiment. This study demonstrates how ventilation pathways at low levels and aloft are affected by surface fluxes, and how ventilation pathways operate, at different times, to affect tropical cyclone development.
Three-Dimensional Structure of the Equatorial Kelvin Wave: Vertical Structure Functions, Equivalent Depths, and Frequency and Wavenumber Spectra
Authors: Žagar Nedjeljka , Lunkeit Frank , Sielmann Frank , Xiao Wenlin 
Published: January 2022

AbstractThe wavenumber filtering of the Kelvin waves (KWs) is performed by a multivariate projection of the ERA5 data on the horizontal structures of the KWs from linear theory and vertical structure functions (VSFs) spanning the troposphere and stratosphere. The associated equivalent depths are consistent with solutions expected for the bounded atmosphere. The zonal wavenumber spectra of the KW energy and temporal variance are shown to be continuous and red with the rotational kinetic energy being dominant over the divergent kinetic energy at zonal wavenumberk= 1. Spatial and temporal variance in wavenumber space is analyzed in terms of periods from linear theory. The strongest variability is found in periods of 8–12 days atk= 1 and VSFs with a single zero-crossing in the troposphere and a structure resembling upward propagating waves across the tropopause and higher up. Secondary maxima are associated with VSFs that have multiple zero crossings in the troposphere and small equivalent depths. A comparison of the wavenumber and wavenumber–frequency methods shows a disagreement between frequencies from the Fourier time series and linear theory. A phase-locking experiment, in which the KW phases are replaced by linear theory estimates, demonstrates that power spectra from wavenumber–frequency filtering in the troposphere are largely defined by wave phases.
Influence of Anthropogenic Warming on the Atlantic Multidecadal Variability and Its Impact on Global Climate in the Twenty-First Century in the MPI-GE Simulations
Authors: Qin Minhua , Dai Aiguo , Hua Wenjian 
Published: January 2022

AbstractThe Atlantic multidecadal variability (AMV), a dominant mode of multidecadal variations in North Atlantic sea surface temperatures (NASST), has major impacts on global climate. Given that both internal variability and external forcing have contributed to the historical AMV, how future anthropogenic forcing may regulate the AMV is of concern but remains unclear. By analyzing observations and a large ensemble of model simulations [i.e., the Max Planck Institute Grand Ensemble (MPI-GE)], the internally generated (AMVIV) and externally forced (AMVEX) components of the AMV and their climatic impacts during the twenty-first century are examined. Consistent with previous findings, the AMVIVwould weaken with future warming by 11%–17% in its amplitude by the end of the twenty-first century, along with reduced warming anomaly over the midlatitude North Atlantic under future warming during the positive AMVIVphases. In contrast, the AMVEXis projected to strengthen with reduced frequency under future warming. Furthermore, future AMVIV-related temperature variations would weaken over Eurasia and North Africa but strengthen over the United States, whereas AMVIV-related precipitation over parts of North America and Eurasia would weaken in a warmer climate. The AMVEX’s impact on global precipitation would also weaken. The results provide new evidence that future anthropogenic forcing (i.e., nonlinear changes in GHGs and aerosols) under different scenarios can generate distinct multidecadal variations and influence the internally generated AMV, and that multidecadal changes in anthropogenic forcing are important for future AMV.
Association between Participation in a Preclinical Surgery Elective and Future Match into Surgical Residency
Authors: Rudasill Sarah , Negrete Manriquez Jose A. , Benharash Peyman , Kim Dennis , Yetasook Amy , Bowens Nina , de Virgilio Christian 
Published: January 2022

Background Since 2013, we have offered a robust “Introduction to Surgery” elective (ITS) for preclinical medical students. The present study investigates whether participants of the ITS elective were more likely to match into surgical residencies than non-ITS participants. Methods This is a retrospective case-control study of medical students from two medical schools in Southern California who participated in the ITS elective and those who did not. Descriptive results and univariate analysis using STATA were utilized to analyze the de-identified data who matched between 2016 and 2021 were included. Results Overall, 87 (8.9%) of the 982 matched students participated in the ITS elective, with an increase in participation from 1.2% in 2016 to 13.9% in 2021 ( P < .001). Among ITS participants, 49.4% matched into a surgical specialty compared to only 22.9% for non-ITS students ( P < .001). There was no difference between ITS and non-ITS students with regards to procedural specialty match (14.9% vs 12.6%, P = .537). Conclusion ITS participants were more than twice as likely to match into a surgical specialty than non-participants. Future qualitative research will help discern the relative impact of the ITS course versus a student’s baseline predisposition to surgery.
Navigation Improves Tumor Ablation Performance: Results From a Novel Liver Tumor Simulator Study
Authors: Kratzke Ian M. , Goss Ryan S. , Razzaque Sharif , Shih Alex , Steele Paula L. , Nurczyk Kamil M. , Gerber David A. 
Published: January 2022

Background The efficacy of microwave ablation in treating hepatic tumors requires advanced ultrasound skills. Failure of proper technique has the potential for either under- or over-treatment and possible harm to the patient. Emprint SX™ navigation provides surgeons with intra-operative, real-time navigation through augmented reality localization of the ablation antenna and the expected ablation zone. We hypothesize that incorporating this technology leads to improved targeting and optimizes ablation coverage. This study utilizes a simulated model to evaluate ablation outcomes using Emprint SX™ navigation vs standard ultrasound. Methods Surgical residents and faculty were recruited from a single institution. Using a novel tumor ablation simulator, participants performed ablations via 2 modes: standard ultrasound guidance (STD) and Emprint SX™ navigation (NAV). Primary outcome was the percentage of under-ablation. Secondary outcomes included percentage of over-ablation, time to complete trial, and number of attempts to position antenna. Results 281 trials were performed by fifteen participants, with 47% female and 60% novice ablationists. Under-ablation volume decreased by a mean of 16.3% (SEM ±12.9, P < .001) with NAV compared to STD. Over-ablation volume decreased by a mean of 14.0% (±8.2, P < .001). NAV time was faster by a mean of 32 seconds (±24.9, P < .001) and involved fewer antenna placement attempts by a mean of 1.3 (±1.0, P < .001). For novice ablationists, all outcomes were improved with NAV and novices saw larger improvements compared to experienced ablationists ( P = .018). Discussion In a simulated model, NAV improves ablation efficacy and efficiency, with novices gaining the greatest benefit over standard ultrasound.
The importance of relational work design characteristics: A person-centred approach
Authors: Knight Caroline , McLarnon Matthew J W , Wenzel Ramon , Parker Sharon 
Published: January 2022

Adopting a person-centred approach, we integrate the job demands-control-support model with relational work design theory to investigate employee work design profiles involving autonomy, workload, social support and prosocial characteristics (representing the combined influence of task significance and beneficiary contact). For a sample of Australian not-for-profit employees ( N = 2421), we identified four work design profiles: ‘active connected’, ‘passive disconnected’, ‘high strain disconnected’ and ‘controlled disconnected’. The most favourable profile, active connected, demonstrated the highest vigour and social worth, and was predicted by people being in higher managerial positions and having permanent employment contracts. The high strain disconnected and controlled disconnected profiles were associated with greater psychological exhaustion. Longer working hours predicted membership of the high strain disconnected profile. JEL Classification: L31, L30, L20, L29
Early and Delayed Surgery for Isolated ACL and Multiligamentous Knee Injuries Have Equivalent Results: A Systematic Review and Meta-analysis
Authors: Vermeijden Harmen D. , Yang Xiuyi A. , Rademakers Maarten V. , Kerkhoffs Gino M.M.J. , van der List Jelle P. , DiFelice Gregory S. 
Published: January 2022

Background: Early surgery for acute ligamentous injuries has recently shown good clinical and functional outcomes. Purpose: To assess the advantages of early vs delayed surgery in patients undergoing isolated anterior cruciate ligament (ACL) or multiligament-injured knee (MLIK) surgery. Study Design: Meta-analyses of Level 1, 2, and 3 studies; Level of evidence, 4. Methods: A systematic search was performed via PubMed, EMBASE, and Cochrane for studies reporting outcomes of timing of surgery after isolated ACL injury or in the MLIK setting using accelerated rehabilitation protocols. Two analyses were conducted to differentiate early and delayed treatment (3- and 6-week cutoffs). Collected outcomes included meniscal or chondral lesions, failure and reoperation rates, range of motion (ROM) deficits, other complications, muscle strength, instrumented laxity, and functional outcomes. Outcomes were reported in risk ratios (RR) or mean differences with 95% CIs. Results: For timing of isolated ACL surgery, 16 studies were included with 2093 patients. High-grade evidence indicated that there were no differences in meniscal or chondral lesions, failure and reoperation rates, stiffness, ROM deficits, complications, muscle strength, instrumented laxity, and functional outcomes between patients treated early and late (all P > .05). When including only studies that set no preoperative criteria for early surgery, the findings were similar. Regarding MLIK surgery, 14 studies were included with 1172 patients. Low evidence was noted for the following: patients treated early had significantly fewer meniscal injuries (RR, 0.7; P = .04) and chondral injuries (RR, 0.5; P < .001), while no differences were found in reoperation rates, complications, stiffness, ROM deficits, muscle strength, instrumented laxity, and functional outcomes between the groups. Other than higher Lysholm scores in the early group for the 3-week analysis (mean difference, 6.8; P = .01), there were no differences between cutoff analyses. Conclusion: This systematic review with meta-analysis found no differences in clinical and functional outcomes between early and delayed surgery for isolated ACL injuries. For MLIK injuries, there were also no differences in surgical outcomes between early and delayed surgery.
CT characterisation and classification of feline temporomandibular joint trauma: a case series of 79 cats
Authors: Mestrinho Lisa A , Sebastião Sónia SF , Zwierucho Maciej A , Lutchman Aaron , Gaschen Lorrie , Goldschmidt Stephanie , Thatcher Graham , Izumisawa Yu , Meeson Richard L 
Published: January 2022

Objectives The aim of this study was to characterise and describe patterns of temporomandibular joint (TMJ) injuries occurring in cats using CT. Methods A cross-sectional study was carried out in adherence with the STROBE guidelines. Among the medical and CT records of 79 cats, 158 TMJs were reviewed in a collaborative study between six institutions. Results TMJ injuries were most commonly unilateral, representing 70.9% of cases. The mandibular condyle was fractured in 88 cases (55.7%) of the 158 TMJs observed. Of those, 84.0% were intra-articular condyle fractures, with the medial half of the mandibular condyle over-represented. Luxations occurred in 32.9% of cases, which was 19.0% of all evaluated TMJs. Rostrodorsal luxations were most common representing 87.0% of all luxations. Temporal bone fractures were observed in 30.4% of all cases, which was 18.4% of TMJs. The majority of fractures were of an unknown cause. When the cause was determined, road traffic accident (RTA) was the most frequent, followed by animal interaction, other external forces (sharp or blunt force) and high-rise trauma. Bilateral injuries were 13.1 times more likely to occur in high-rise trauma ( P = 0.01) and temporal bone fracture was significantly associated with RTAs ( P = 0.016). No other significant associations were observed between cause of injury and the resulting TMJ injury pattern. Conclusions and relevance Various TMJ injury patterns can occur in cats as a result of trauma. Intra-articular fractures of the medial half of the mandibular condyle occur most commonly. Although unilateral injuries are more frequent, high-rise trauma tends to present with bilateral lesions. Further studies with a larger sample size should be performed to better understand TMJ patterns of injury and how they relate to possible causes.
Agreement between anterior segment swept source-OCT and Scheimpflug imaging corneal aberration measurements in healthy eyes
Authors: Pérez–Bartolomé Francisco , Feu-Basilio Silvia , Rocha-de Lossada Carlos , Blanco-Dominguez Irene , Torras-Sanvicens Josep , Peraza-Nieves Jorge 
Published: January 2022

Purpose To assess agreement between corneal aberration measurements made through swept-source optical coherence tomography using a new anterior segment imaging device (Anterion) and a Scheimpflug imaging device (Pentacam HR) in healthy subjects. Methods Cross-sectional study. In 50 eyes of 50 healthy subjects, 14 aberration parameters (7 across the anterior corneal surface and 7 across the total surface) were measured in 4 mm and 6 mm optic zones using each device: oblique trefoil (Z3_-3), vertical coma (Z3_-1), horizontal coma (Z3_1), horizontal trefoil (Z3_3), spherical aberration (Z4_0), root mean square (RMS) lower order aberrations (LOA) and RMS higher order aberrations (HOA). Data for the two devices were compared through intraclass correlation coefficients (ICC), paired t tests, limits of agreement (LoA) and Bland Altman plots. Results Vertical coma was the only corneal aberration parameter that consistently showed excellent agreement (ICC > 0.8, mean difference −0.019, LoA −0.165 to 0.126). Good agreement (ICC = 0.75) between the devices was observed for RMS HOA, but this was slightly worse in the 6 mm optical zone (ICC = 0.667 for anterior RMS HOA). No over- or underestimation trend by one or other device was noted. Agreement was poor to moderate for the rest of the corneal parameters (ICC 0.2 to 0.7). Conclusion Despite good agreement overall for vertical coma and RMS HOA values, agreement for the remaining corneal aberration measurements was poor to moderate. As mean differences in our sample were overall small, in normal eyes these devices could be clinically judged as interchangeable.
Effects of Probiotics on Allergic Rhinitis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
Authors: Farahmandi Kajal , Mohr Alex E. , McFarland Lynne V. 
Published: January 2022

Background The prevalence of allergic rhinitis has been estimated to range from 10 to 30% in adults and up to 40% in children. Probiotics have been tested as for this condition, but no census on which probiotic types are most effective. Objective Our aim of this study was to provide probiotic strain-specific evaluation for the treatment of allergic rhinitis. Methods Databases (PubMed, Google Scholar, and ScienceDirect) were searched (from inception to October 2020) to identify randomized controlled trials (RCTs) of probiotic treatments in allergic rhinitis patients. A systematic review was done comparing types of reported outcomes, clinical and immunological parameters and safety data. A meta-analysis was done for probiotics with at least two RCTs per probiotic strain(s) and sharing a common outcome. Results A total of 13 randomized, double-blind, placebo-controlled trials (N = 1591 participants) were included in the systematic review. Overall, 8 of 9 probiotic types alleviated at least one clinical symptom of allergic rhinitis. The meta-analysis results showed that, neither L. paracasei Lp33 (SMD = −1.61, 95% CI −4.67, 1.45) nor L. rhamnosus GG (SMD = −1.00, 95% CI −3.01, 1.00) had significant efficacy for reducing nasal symptom scores. Conclusions Our analysis showed probiotics produced a slight improvement in some clinical and immunological measurements on allergic rhinitis. Due to the diversity of outcome measurements and lack of sufficient trials for each probiotic strain, future trials are needed with similar study design and uniform outcomes to better compare the effect of probiotics on allergic rhinitis.
The Effect of Bone Marrow Stimulation for Cartilage Repair on the Subchondral Bone Plate
Authors: Elmholt Simone Birkebæk , Hede Kris Chadwick , Christensen Bjørn Borsøe , Thomsen Jesper Skovhus , Lind Martin 
Published: January 2022

Purpose To investigate the effect of bone-marrow stimulation (BMS) on subchondral bone plate morphology and remodeling compared to untreated subchondral bone in a validated minipig model. Methods Three Göttingen minipigs received BMS with drilling as treatment for two chondral defects in each knee. The animals were euthanized after six months. Follow-up consisted of a histological semiquantitative evaluation using a novel subchondral bone scoring system and micro computed tomography (µCT) of the BMS subchondral bone. The histological and microstructural properties of the BMS-treated subchondral bone were compared to that of the adjacent healthy subchondral bone. Results The µCT analysis showed that subchondral bone treated with BMS had significantly higher connectivity density compared to adjacent untreated subchondral bone (26 1/mm3 vs. 21 1/mm3, P = 0.048). This was the only microstructural parameter showing a significant difference. The histological semiquantitative score differed significantly between the subchondral bone treated with BMS and the adjacent untreated subchondral (8.0 vs. 10 P = < 0.001). Surface irregularities were seen in 43% and bone overgrowth in 27% of the histological sections. Only sparse formation of bone cysts was detected (1%). Conclusions BMS with drilling does not cause extensive changes to the subchondral bone microarchitecture. Furthermore, the morphology of BMS subchondral bone resembled that of untreated subchondral bone with almost no formation of bone cyst, but some surface irregularities and bone overgrowth.
Platform work in Europe: Lessons learned, legal developments and challenges ahead
Authors: Aloisi Antonio 
Published: January 2022

Several years since first emerging in Europe, platform work continues to represent a ‘social dilemma’ for workers, social partners, policymakers and society as a whole. As a result of intense litigation, analysis and reporting, much is known about the contractual and working conditions in this growing labour market segment. While the European Union (EU) institutions are considering adopting a new Directive based on Art. 153 TFEU, there are a number of significant top-down and bottom-up national cases worth discussing. Workers across Europe have been reclassified by many courts; some governments have taken regulatory initiatives to address the risk of precariousness and have implemented new comprehensive legal instruments to safeguard a level playing field for both workers and platforms. This article discusses how existing and new domestic and EU labour law provisions can improve the labour conditions of platform workers. Its overarching goal is to address possible policy gaps and the implications for EU social law by exploring the lessons that can be drawn from recent policies and legal developments. Section two briefly touches upon the policymaking initiatives in France, Spain and Italy. Moreover, it presents and reviews the main outcomes of litigation at the domestic level, focusing on the pervasive role played by algorithmic management. After introducing the Pillar of Social Rights (EPSR), section three critically analyses two key achievements at the EU level: the Directive on transparent and predictable working conditions and the Recommendation on access to social protection for workers and the self-employed. Section four explores the elasticity of the triad of Directives that regulate atypical forms of employment (part-time, fixed-term and temporary agency work). It is argued that the narrow construction of the Directives’ scope of application could represent an obstacle. However, an adaptive and purposive approach by the Court of Justice of the European Union (CJEU) could result in the classification of platform workers as falling within the scope of the social acquis in certain fields. Finally, section five concludes by providing concrete policy proposals focussed on cross-border issues, algorithmic transparency, the introduction of a presumption of employment status and collective bargaining.